[ { "uniprot_canonical_ac": "A0A0G2KBA6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KBA6", "url": "https://www.uniprot.org/uniprotkb/A0A0G2KBA6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 275, "chemical_mass": 30798.0, "gene_names": "LOC120099259;4933416I08Rikl;LOC100910451;LOC120099259", "protein_name": "S1-like RNA binding domain-containing protein", "disease": [ { "disease_id": "DOID:0070598", "name": "X-linked spermatogenic failure 7", "description": "A spermatogenic failure characterized by sperm with insufficient individualization, excessive residual cytoplasm, acrosome defects, and abnormalities of the head and flagella, resulting in significantly reduced sperm concentration and progressive motility, that has_material_basis_in hemizygous mutation in the CT55 gene on chromosome Xq26.3.", "url": "https://disease-ontology.org/term/DOID:0070598", "evidence": [ { "id": "0070598", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070598" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KBA6", "url": "https://www.uniprot.org/uniprotkb/A0A0G2KBA6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A0G2KBA6-1" }, { "uniprot_canonical_ac": "A0A0G2QC39-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A0G2QC39", "url": "https://www.uniprot.org/uniprotkb/A0A0G2QC39" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 530, "chemical_mass": 60791.0, "gene_names": "Txlng;Txlng", "protein_name": "", "disease": [], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2QC39", "url": "https://www.uniprot.org/uniprotkb/A0A0G2QC39" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2QC39", "url": "https://www.uniprot.org/uniprotkb/A0A0G2QC39" } ], "pmid": "" } ], "molecular_function": [ { "name": "syntaxin binding", "id": "GO:0019905", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019905", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2QC39", "url": "https://www.uniprot.org/uniprotkb/A0A0G2QC39" } ], "pmid": "" }, { "name": "DNA-binding transcription factor binding", "id": "GO:0140297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140297", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2QC39", "url": "https://www.uniprot.org/uniprotkb/A0A0G2QC39" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of bone mineralization", "id": "GO:0030500", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030500", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2QC39", "url": "https://www.uniprot.org/uniprotkb/A0A0G2QC39" } ], "pmid": "" }, { "name": "regulation of cell cycle process", "id": "GO:0010564", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010564", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2QC39", "url": "https://www.uniprot.org/uniprotkb/A0A0G2QC39" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2QC39", "url": "https://www.uniprot.org/uniprotkb/A0A0G2QC39" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A0G2QC39-1" }, { "uniprot_canonical_ac": "A0A0G2QC52-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A0G2QC52", "url": "https://www.uniprot.org/uniprotkb/A0A0G2QC52" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 250, "chemical_mass": 28558.0, "gene_names": "Rabl2;Rabl2a;Rabl2b;Rabl2", "protein_name": "small monomeric GTPase", "disease": [], "molecular_function": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2QC52", "url": "https://www.uniprot.org/uniprotkb/A0A0G2QC52" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2QC52", "url": "https://www.uniprot.org/uniprotkb/A0A0G2QC52" } ], "pmid": "" }, { "name": "G protein activity", "id": "GO:0003925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003925", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2QC52", "url": "https://www.uniprot.org/uniprotkb/A0A0G2QC52" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2QC52", "url": "https://www.uniprot.org/uniprotkb/A0A0G2QC52" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2QC52", "url": "https://www.uniprot.org/uniprotkb/A0A0G2QC52" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2QC52", "url": "https://www.uniprot.org/uniprotkb/A0A0G2QC52" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2QC52", "url": "https://www.uniprot.org/uniprotkb/A0A0G2QC52" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2QC52", "url": "https://www.uniprot.org/uniprotkb/A0A0G2QC52" } ], "pmid": "" }, { "name": "sperm midpiece", "id": "GO:0097225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097225", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2QC52", "url": "https://www.uniprot.org/uniprotkb/A0A0G2QC52" } ], "pmid": "" }, { "name": "pericentriolar material", "id": "GO:0000242", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000242", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2QC52", "url": "https://www.uniprot.org/uniprotkb/A0A0G2QC52" } ], "pmid": "" }, { "name": "intraciliary transport particle B", "id": "GO:0030992", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030992", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2QC52", "url": "https://www.uniprot.org/uniprotkb/A0A0G2QC52" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2QC52", "url": "https://www.uniprot.org/uniprotkb/A0A0G2QC52" } ], "pmid": "" }, { "name": "flagellated sperm motility", "id": "GO:0030317", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030317", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2QC52", "url": "https://www.uniprot.org/uniprotkb/A0A0G2QC52" } ], "pmid": "" }, { "name": "single fertilization", "id": "GO:0007338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007338", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2QC52", "url": "https://www.uniprot.org/uniprotkb/A0A0G2QC52" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2QC52", "url": "https://www.uniprot.org/uniprotkb/A0A0G2QC52" } ], "pmid": "" }, { "name": "intraciliary transport", "id": "GO:0042073", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042073", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2QC52", "url": "https://www.uniprot.org/uniprotkb/A0A0G2QC52" } ], "pmid": "" }, { "name": "photoreceptor cell morphogenesis", "id": "GO:0008594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008594", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2QC52", "url": "https://www.uniprot.org/uniprotkb/A0A0G2QC52" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A0G2QC52-1" }, { "uniprot_canonical_ac": "A0A0H2UHJ3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A0H2UHJ3", "url": "https://www.uniprot.org/uniprotkb/A0A0H2UHJ3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 113, "chemical_mass": 11561.0, "gene_names": "Rplp1l1;RGD1564744;Rplp1l1", "protein_name": "Large ribosomal subunit protein P1", "disease": [ { "disease_id": "DOID:0060036", "name": "intrinsic cardiomyopathy", "description": "A cardiomyopathy that is characterized as weakness in the muscle of the heart that is not due to an identifiable external cause.", "url": "https://disease-ontology.org/term/DOID:0060036", "evidence": [ { "id": "0060036", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060036" } ], "weight": 0.0 } ], "biological_process": [ { "name": "regulation of translation", "id": "GO:0006417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006417", "evidence": [ { "database": "UniProtKB", "id": "A0A0H2UHJ3", "url": "https://www.uniprot.org/uniprotkb/A0A0H2UHJ3" } ], "pmid": "" }, { "name": "translational elongation", "id": "GO:0006414", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006414", "evidence": [ { "database": "UniProtKB", "id": "A0A0H2UHJ3", "url": "https://www.uniprot.org/uniprotkb/A0A0H2UHJ3" } ], "pmid": "" }, { "name": "cytoplasmic translation", "id": "GO:0002181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002181", "evidence": [ { "database": "UniProtKB", "id": "A0A0H2UHJ3", "url": "https://www.uniprot.org/uniprotkb/A0A0H2UHJ3" } ], "pmid": "" } ], "molecular_function": [ { "name": "ribonucleoprotein complex binding", "id": "GO:0043021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043021", "evidence": [ { "database": "UniProtKB", "id": "A0A0H2UHJ3", "url": "https://www.uniprot.org/uniprotkb/A0A0H2UHJ3" } ], "pmid": "" }, { "name": "protein kinase activator activity", "id": "GO:0030295", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030295", "evidence": [ { "database": "UniProtKB", "id": "A0A0H2UHJ3", "url": "https://www.uniprot.org/uniprotkb/A0A0H2UHJ3" } ], "pmid": "" }, { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "A0A0H2UHJ3", "url": "https://www.uniprot.org/uniprotkb/A0A0H2UHJ3" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosolic large ribosomal subunit", "id": "GO:0022625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022625", "evidence": [ { "database": "UniProtKB", "id": "A0A0H2UHJ3", "url": "https://www.uniprot.org/uniprotkb/A0A0H2UHJ3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A0H2UHJ3-1" }, { "uniprot_canonical_ac": "A0A0R4J8U1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A0R4J8U1", "url": "https://www.uniprot.org/uniprotkb/A0A0R4J8U1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 708, "chemical_mass": 79945.0, "gene_names": "Zap70", "protein_name": "Tyrosine-protein kinase", "disease": [ { "disease_id": "DOID:0061161", "name": "infantile onset multisystem autoimmune disease 2", "description": "An infantile onset multisystem autoimmune disease that has_material_basis_in compound heterozygous mutation in the ZAP70 gene on chromosome 2q12.", "url": "https://disease-ontology.org/term/DOID:0061161", "evidence": [ { "id": "0061161", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061161" } ], "weight": 0.0 }, { "disease_id": "DOID:0111943", "name": "immunodeficiency 48", "description": "A T cell deficiency characterized by a selective T cell defect where circulating T cells exclusively express CD4, CD3, and T-cell receptor-alpha/beta and not CD8 on their surfaces that has_material_basis_in homozygous or compound heterozygous mutation in the ZAP70 gene on chromosome 2q11.2.", "url": "https://disease-ontology.org/term/DOID:0111943", "evidence": [ { "id": "0111943", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111943" } ], "weight": 0.0 }, { "disease_id": "DOID:627", "name": "severe combined immunodeficiency", "description": "A combined T cell and B cell immunodeficiency that is caused by a defect in infection-fighting immune cells resulting in individuals with non-functional immune systems.", "url": "https://disease-ontology.org/term/DOID:627", "evidence": [ { "id": "627", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:627" } ], "weight": 0.0 }, { "disease_id": "DOID:7148", "name": "rheumatoid arthritis", "description": "An arthritis that is an autoimmune disease which attacks healthy cells and tissue located_in joint.", "url": "https://disease-ontology.org/term/DOID:7148", "evidence": [ { "id": "7148", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7148" } ], "weight": 0.0 } ], "biological_process": [ { "name": "thymic T cell selection", "id": "GO:0045061", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045061", "evidence": [ { "database": "UniProtKB", "id": "A0A0R4J8U1", "url": "https://www.uniprot.org/uniprotkb/A0A0R4J8U1" } ], "pmid": "" }, { "name": "protein phosphorylation", "id": "GO:0006468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006468", "evidence": [ { "database": "UniProtKB", "id": "A0A0R4J8U1", "url": "https://www.uniprot.org/uniprotkb/A0A0R4J8U1" } ], "pmid": "" }, { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "A0A0R4J8U1", "url": "https://www.uniprot.org/uniprotkb/A0A0R4J8U1" } ], "pmid": "" }, { "name": "peptidyl-tyrosine phosphorylation", "id": "GO:0018108", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018108", "evidence": [ { "database": "UniProtKB", "id": "A0A0R4J8U1", "url": "https://www.uniprot.org/uniprotkb/A0A0R4J8U1" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A0R4J8U1", "url": "https://www.uniprot.org/uniprotkb/A0A0R4J8U1" } ], "pmid": "" }, { "name": "T cell activation", "id": "GO:0042110", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042110", "evidence": [ { "database": "UniProtKB", "id": "A0A0R4J8U1", "url": "https://www.uniprot.org/uniprotkb/A0A0R4J8U1" } ], "pmid": "" }, { "name": "T cell receptor signaling pathway", "id": "GO:0050852", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050852", "evidence": [ { "database": "UniProtKB", "id": "A0A0R4J8U1", "url": "https://www.uniprot.org/uniprotkb/A0A0R4J8U1" } ], "pmid": "" }, { "name": "positive regulation of alpha-beta T cell differentiation", "id": "GO:0046638", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046638", "evidence": [ { "database": "UniProtKB", "id": "A0A0R4J8U1", "url": "https://www.uniprot.org/uniprotkb/A0A0R4J8U1" } ], "pmid": "" }, { "name": "protein autophosphorylation", "id": "GO:0046777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046777", "evidence": [ { "database": "UniProtKB", "id": "A0A0R4J8U1", "url": "https://www.uniprot.org/uniprotkb/A0A0R4J8U1" } ], "pmid": "" }, { "name": "positive regulation of calcium-mediated signaling", "id": "GO:0050850", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050850", "evidence": [ { "database": "UniProtKB", "id": "A0A0R4J8U1", "url": "https://www.uniprot.org/uniprotkb/A0A0R4J8U1" } ], "pmid": "" }, { "name": "negative thymic T cell selection", "id": "GO:0045060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045060", "evidence": [ { "database": "UniProtKB", "id": "A0A0R4J8U1", "url": "https://www.uniprot.org/uniprotkb/A0A0R4J8U1" } ], "pmid": "" }, { "name": "beta selection", "id": "GO:0043366", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043366", "evidence": [ { "database": "UniProtKB", "id": "A0A0R4J8U1", "url": "https://www.uniprot.org/uniprotkb/A0A0R4J8U1" } ], "pmid": "" }, { "name": "positive thymic T cell selection", "id": "GO:0045059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045059", "evidence": [ { "database": "UniProtKB", "id": "A0A0R4J8U1", "url": "https://www.uniprot.org/uniprotkb/A0A0R4J8U1" } ], "pmid": "" }, { "name": "positive regulation of T cell differentiation", "id": "GO:0045582", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045582", "evidence": [ { "database": "UniProtKB", "id": "A0A0R4J8U1", "url": "https://www.uniprot.org/uniprotkb/A0A0R4J8U1" } ], "pmid": "" }, { "name": "positive regulation of alpha-beta T cell proliferation", "id": "GO:0046641", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046641", "evidence": [ { "database": "UniProtKB", "id": "A0A0R4J8U1", "url": "https://www.uniprot.org/uniprotkb/A0A0R4J8U1" } ], "pmid": "" }, { "name": "regulation of immune response", "id": "GO:0050776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050776", "evidence": [ { "database": "UniProtKB", "id": "A0A0R4J8U1", "url": "https://www.uniprot.org/uniprotkb/A0A0R4J8U1" } ], "pmid": "" }, { "name": "positive regulation of immune system process", "id": "GO:0002684", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002684", "evidence": [ { "database": "UniProtKB", "id": "A0A0R4J8U1", "url": "https://www.uniprot.org/uniprotkb/A0A0R4J8U1" } ], "pmid": "" }, { "name": "immune system process", "id": "GO:0002376", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002376", "evidence": [ { "database": "UniProtKB", "id": "A0A0R4J8U1", "url": "https://www.uniprot.org/uniprotkb/A0A0R4J8U1" } ], "pmid": "" } ], "molecular_function": [ { "name": "phosphotyrosine residue binding", "id": "GO:0001784", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001784", "evidence": [ { "database": "UniProtKB", "id": "A0A0R4J8U1", "url": "https://www.uniprot.org/uniprotkb/A0A0R4J8U1" } ], "pmid": "" }, { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "A0A0R4J8U1", "url": "https://www.uniprot.org/uniprotkb/A0A0R4J8U1" } ], "pmid": "" }, { "name": "protein tyrosine kinase activity", "id": "GO:0004713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004713", "evidence": [ { "database": "UniProtKB", "id": "A0A0R4J8U1", "url": "https://www.uniprot.org/uniprotkb/A0A0R4J8U1" } ], "pmid": "" }, { "name": "non-membrane spanning protein tyrosine kinase activity", "id": "GO:0004715", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004715", "evidence": [ { "database": "UniProtKB", "id": "A0A0R4J8U1", "url": "https://www.uniprot.org/uniprotkb/A0A0R4J8U1" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A0R4J8U1", "url": "https://www.uniprot.org/uniprotkb/A0A0R4J8U1" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A0R4J8U1", "url": "https://www.uniprot.org/uniprotkb/A0A0R4J8U1" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A0R4J8U1", "url": "https://www.uniprot.org/uniprotkb/A0A0R4J8U1" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A0R4J8U1", "url": "https://www.uniprot.org/uniprotkb/A0A0R4J8U1" } ], "pmid": "" }, { "name": "cell-cell junction", "id": "GO:0005911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005911", "evidence": [ { "database": "UniProtKB", "id": "A0A0R4J8U1", "url": "https://www.uniprot.org/uniprotkb/A0A0R4J8U1" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A0R4J8U1", "url": "https://www.uniprot.org/uniprotkb/A0A0R4J8U1" } ], "pmid": "" }, { "name": "T cell receptor complex", "id": "GO:0042101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042101", "evidence": [ { "database": "UniProtKB", "id": "A0A0R4J8U1", "url": "https://www.uniprot.org/uniprotkb/A0A0R4J8U1" } ], "pmid": "" }, { "name": "membrane raft", "id": "GO:0045121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045121", "evidence": [ { "database": "UniProtKB", "id": "A0A0R4J8U1", "url": "https://www.uniprot.org/uniprotkb/A0A0R4J8U1" } ], "pmid": "" }, { "name": "immunological synapse", "id": "GO:0001772", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001772", "evidence": [ { "database": "UniProtKB", "id": "A0A0R4J8U1", "url": "https://www.uniprot.org/uniprotkb/A0A0R4J8U1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A0R4J8U1-1" }, { "uniprot_canonical_ac": "A0A0U1RRY7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A0U1RRY7", "url": "https://www.uniprot.org/uniprotkb/A0A0U1RRY7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 590, "chemical_mass": 63128.0, "gene_names": "Mnt;Mnt", "protein_name": "Max-binding protein MNT", "disease": [ { "disease_id": "DOID:0060469", "name": "Miller-Dieker lissencephaly syndrome", "description": "A syndrome characterized by classical lissencephaly and distinct facial features and has_material_basis_in submicroscopic deletions of 17p13.3, including the LIS1 gene.", "url": "https://disease-ontology.org/term/DOID:0060469", "evidence": [ { "id": "0060469", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060469" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A0U1RRY7", "url": "https://www.uniprot.org/uniprotkb/A0A0U1RRY7" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A0U1RRY7", "url": "https://www.uniprot.org/uniprotkb/A0A0U1RRY7" } ], "pmid": "" }, { "name": "Mad-Max complex", "id": "GO:0070443", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070443", "evidence": [ { "database": "UniProtKB", "id": "A0A0U1RRY7", "url": "https://www.uniprot.org/uniprotkb/A0A0U1RRY7" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A0U1RRY7", "url": "https://www.uniprot.org/uniprotkb/A0A0U1RRY7" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A0U1RRY7", "url": "https://www.uniprot.org/uniprotkb/A0A0U1RRY7" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A0U1RRY7", "url": "https://www.uniprot.org/uniprotkb/A0A0U1RRY7" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A0U1RRY7", "url": "https://www.uniprot.org/uniprotkb/A0A0U1RRY7" } ], "pmid": "" }, { "name": "cellular senescence", "id": "GO:0090398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090398", "evidence": [ { "database": "UniProtKB", "id": "A0A0U1RRY7", "url": "https://www.uniprot.org/uniprotkb/A0A0U1RRY7" } ], "pmid": "" }, { "name": "negative regulation of apoptotic signaling pathway", "id": "GO:2001234", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001234", "evidence": [ { "database": "UniProtKB", "id": "A0A0U1RRY7", "url": "https://www.uniprot.org/uniprotkb/A0A0U1RRY7" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "A0A0U1RRY7", "url": "https://www.uniprot.org/uniprotkb/A0A0U1RRY7" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "A0A0U1RRY7", "url": "https://www.uniprot.org/uniprotkb/A0A0U1RRY7" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A0U1RRY7", "url": "https://www.uniprot.org/uniprotkb/A0A0U1RRY7" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A0U1RRY7", "url": "https://www.uniprot.org/uniprotkb/A0A0U1RRY7" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A0U1RRY7", "url": "https://www.uniprot.org/uniprotkb/A0A0U1RRY7" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A0U1RRY7", "url": "https://www.uniprot.org/uniprotkb/A0A0U1RRY7" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A0U1RRY7", "url": "https://www.uniprot.org/uniprotkb/A0A0U1RRY7" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A0U1RRY7", "url": "https://www.uniprot.org/uniprotkb/A0A0U1RRY7" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "A0A0U1RRY7", "url": "https://www.uniprot.org/uniprotkb/A0A0U1RRY7" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "A0A0U1RRY7", "url": "https://www.uniprot.org/uniprotkb/A0A0U1RRY7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A0U1RRY7-1", "start_pos": "147", "end_pos": "147", "site_lbl": "Thr147", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 147, "start_aa": "Thr", "end_pos": 147, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr147", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A0U1RRY7-1", "start_pos": "162", "end_pos": "162", "site_lbl": "Thr162", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 162, "start_aa": "Thr", "end_pos": 162, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr162", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A0U1RRY7-1", "start_pos": "173", "end_pos": "173", "site_lbl": "Thr173", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 173, "start_aa": "Thr", "end_pos": 173, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr173", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A0U1RRY7-1", "start_pos": "372", "end_pos": "372", "site_lbl": "Thr372", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 372, "start_aa": "Thr", "end_pos": 372, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr372", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A0U1RRY7-1", "start_pos": "420", "end_pos": "420", "site_lbl": "Thr420", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 420, "start_aa": "Thr", "end_pos": 420, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr420", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A0U1RRY7-1", "start_pos": "84", "end_pos": "84", "site_lbl": "Thr84", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 84, "start_aa": "Thr", "end_pos": 84, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr84", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A0U1RRY7-1" }, { "uniprot_canonical_ac": "A0A0U1RRZ3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A0U1RRZ3", "url": "https://www.uniprot.org/uniprotkb/A0A0U1RRZ3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 786, "chemical_mass": 88420.0, "gene_names": "Nkrf;Nkrf", "protein_name": "NF-kappa-B-repressing factor", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A0U1RRZ3", "url": "https://www.uniprot.org/uniprotkb/A0A0U1RRZ3" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A0U1RRZ3", "url": "https://www.uniprot.org/uniprotkb/A0A0U1RRZ3" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A0U1RRZ3", "url": "https://www.uniprot.org/uniprotkb/A0A0U1RRZ3" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A0U1RRZ3", "url": "https://www.uniprot.org/uniprotkb/A0A0U1RRZ3" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A0U1RRZ3", "url": "https://www.uniprot.org/uniprotkb/A0A0U1RRZ3" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A0U1RRZ3", "url": "https://www.uniprot.org/uniprotkb/A0A0U1RRZ3" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A0U1RRZ3", "url": "https://www.uniprot.org/uniprotkb/A0A0U1RRZ3" } ], "pmid": "" }, { "name": "ATPase activator activity", "id": "GO:0001671", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001671", "evidence": [ { "database": "UniProtKB", "id": "A0A0U1RRZ3", "url": "https://www.uniprot.org/uniprotkb/A0A0U1RRZ3" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A0U1RRZ3", "url": "https://www.uniprot.org/uniprotkb/A0A0U1RRZ3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A0U1RRZ3-1" }, { "uniprot_canonical_ac": "A0A1B0GWQ8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A1B0GWQ8", "url": "https://www.uniprot.org/uniprotkb/A0A1B0GWQ8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1733, "chemical_mass": 183886.0, "gene_names": "Mbd5;Mbd5", "protein_name": "Methyl-CpG-binding domain protein 5", "disease": [ { "disease_id": "DOID:0060041", "name": "autism spectrum disorder", "description": "A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior.", "url": "https://disease-ontology.org/term/DOID:0060041", "evidence": [ { "id": "0060041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060041" } ], "weight": 0.0 }, { "disease_id": "DOID:0060307", "name": "autosomal dominant intellectual developmental disorder", "description": "A intellectual disability characterized by an autosomal dominant inheritance pattern.", "url": "https://disease-ontology.org/term/DOID:0060307", "evidence": [ { "id": "0060307", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060307" } ], "weight": 0.0 }, { "disease_id": "DOID:0070031", "name": "autosomal dominant intellectual developmental disorder 1", "description": "An autosomal dominant intellectual developmental disorder that has_material_basis_in an autosomal dominant mutation of the MBD5 gene on chromosome 2q23.1.", "url": "https://disease-ontology.org/term/DOID:0070031", "evidence": [ { "id": "0070031", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070031" } ], "weight": 0.0 } ], "biological_process": [ { "name": "positive regulation of growth hormone receptor signaling pathway", "id": "GO:0060399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060399", "evidence": [ { "database": "UniProtKB", "id": "A0A1B0GWQ8", "url": "https://www.uniprot.org/uniprotkb/A0A1B0GWQ8" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A0A1B0GWQ8", "url": "https://www.uniprot.org/uniprotkb/A0A1B0GWQ8" } ], "pmid": "" }, { "name": "regulation of multicellular organism growth", "id": "GO:0040014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040014", "evidence": [ { "database": "UniProtKB", "id": "A0A1B0GWQ8", "url": "https://www.uniprot.org/uniprotkb/A0A1B0GWQ8" } ], "pmid": "" }, { "name": "glucose homeostasis", "id": "GO:0042593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042593", "evidence": [ { "database": "UniProtKB", "id": "A0A1B0GWQ8", "url": "https://www.uniprot.org/uniprotkb/A0A1B0GWQ8" } ], "pmid": "" }, { "name": "regulation of behavior", "id": "GO:0050795", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050795", "evidence": [ { "database": "UniProtKB", "id": "A0A1B0GWQ8", "url": "https://www.uniprot.org/uniprotkb/A0A1B0GWQ8" } ], "pmid": "" } ], "molecular_function": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A1B0GWQ8", "url": "https://www.uniprot.org/uniprotkb/A0A1B0GWQ8" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1B0GWQ8", "url": "https://www.uniprot.org/uniprotkb/A0A1B0GWQ8" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A1B0GWQ8", "url": "https://www.uniprot.org/uniprotkb/A0A1B0GWQ8" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "A0A1B0GWQ8", "url": "https://www.uniprot.org/uniprotkb/A0A1B0GWQ8" } ], "pmid": "" }, { "name": "chromocenter", "id": "GO:0010369", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010369", "evidence": [ { "database": "UniProtKB", "id": "A0A1B0GWQ8", "url": "https://www.uniprot.org/uniprotkb/A0A1B0GWQ8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A1B0GWQ8-1", "start_pos": "720", "end_pos": "720", "site_lbl": "Thr720", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 720, "start_aa": "Thr", "end_pos": 720, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr720", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A1B0GWQ8-1" }, { "uniprot_canonical_ac": "D3Z840-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3Z840", "url": "https://www.uniprot.org/uniprotkb/D3Z840" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1332, "chemical_mass": 149536.0, "gene_names": "Fanci;Fanci", "protein_name": "", "disease": [ { "disease_id": "DOID:0050671", "name": "female breast cancer", "description": "A breast cancer that develops from breast tissue in females.", "url": "https://disease-ontology.org/term/DOID:0050671", "evidence": [ { "id": "0050671", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050671" } ], "weight": 0.0 }, { "disease_id": "DOID:0050865", "name": "tongue squamous cell carcinoma", "description": "A head and neck squamous cell carcinoma that is located_in the tongue.", "url": "https://disease-ontology.org/term/DOID:0050865", "evidence": [ { "id": "0050865", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050865" } ], "weight": 0.0 }, { "disease_id": "DOID:0111091", "name": "Fanconi anemia complementation group I", "description": "A Fanconi anemia that has_material_basis_in homozygous or compound heterozygous mutation in the FANCI gene on chromosome 15q26.", "url": "https://disease-ontology.org/term/DOID:0111091", "evidence": [ { "id": "0111091", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111091" } ], "weight": 0.0 }, { "disease_id": "DOID:13636", "name": "Fanconi anemia", "description": "A congenital hypoplastic anemia characterized by progressive pancytopenia with bone marrow failure, variable congenital malformations and predisposition to develop hematological or solid tumors. It is a result of a genetic defect in a cluster of proteins responsible for DNA repair.", "url": "https://disease-ontology.org/term/DOID:13636", "evidence": [ { "id": "13636", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13636" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "D3Z840", "url": "https://www.uniprot.org/uniprotkb/D3Z840" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "D3Z840", "url": "https://www.uniprot.org/uniprotkb/D3Z840" } ], "pmid": "" }, { "name": "DNA repair complex", "id": "GO:1990391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990391", "evidence": [ { "database": "UniProtKB", "id": "D3Z840", "url": "https://www.uniprot.org/uniprotkb/D3Z840" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "D3Z840", "url": "https://www.uniprot.org/uniprotkb/D3Z840" } ], "pmid": "" }, { "name": "positive regulation of protein ubiquitination", "id": "GO:0031398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031398", "evidence": [ { "database": "UniProtKB", "id": "D3Z840", "url": "https://www.uniprot.org/uniprotkb/D3Z840" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA polymerase binding", "id": "GO:0070182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070182", "evidence": [ { "database": "UniProtKB", "id": "D3Z840", "url": "https://www.uniprot.org/uniprotkb/D3Z840" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3Z840-1" }, { "uniprot_canonical_ac": "D3Z8A6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3Z8A6", "url": "https://www.uniprot.org/uniprotkb/D3Z8A6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 312, "chemical_mass": 35025.0, "gene_names": "Or14j3;LOC100365012", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "D3Z8A6", "url": "https://www.uniprot.org/uniprotkb/D3Z8A6" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "D3Z8A6", "url": "https://www.uniprot.org/uniprotkb/D3Z8A6" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "D3Z8A6", "url": "https://www.uniprot.org/uniprotkb/D3Z8A6" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "D3Z8A6", "url": "https://www.uniprot.org/uniprotkb/D3Z8A6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3Z8A6-1" }, { "uniprot_canonical_ac": "D3Z8G4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3Z8G4", "url": "https://www.uniprot.org/uniprotkb/D3Z8G4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1219, "chemical_mass": 135457.0, "gene_names": "Adamts18;Adamts18;RGD1560118", "protein_name": "A disintegrin and metalloproteinase with thrombospondin motifs 18", "disease": [], "molecular_function": [ { "name": "metalloendopeptidase activity", "id": "GO:0004222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004222", "evidence": [ { "database": "UniProtKB", "id": "D3Z8G4", "url": "https://www.uniprot.org/uniprotkb/D3Z8G4" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "D3Z8G4", "url": "https://www.uniprot.org/uniprotkb/D3Z8G4" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "D3Z8G4", "url": "https://www.uniprot.org/uniprotkb/D3Z8G4" } ], "pmid": "" }, { "name": "extracellular matrix organization", "id": "GO:0030198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030198", "evidence": [ { "database": "UniProtKB", "id": "D3Z8G4", "url": "https://www.uniprot.org/uniprotkb/D3Z8G4" } ], "pmid": "" }, { "name": "negative regulation of platelet aggregation", "id": "GO:0090331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090331", "evidence": [ { "database": "UniProtKB", "id": "D3Z8G4", "url": "https://www.uniprot.org/uniprotkb/D3Z8G4" } ], "pmid": "" }, { "name": "eye development", "id": "GO:0001654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001654", "evidence": [ { "database": "UniProtKB", "id": "D3Z8G4", "url": "https://www.uniprot.org/uniprotkb/D3Z8G4" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "D3Z8G4", "url": "https://www.uniprot.org/uniprotkb/D3Z8G4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3Z8G4-1" }, { "uniprot_canonical_ac": "D3Z8M1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3Z8M1", "url": "https://www.uniprot.org/uniprotkb/D3Z8M1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 329, "chemical_mass": 36068.0, "gene_names": "Or2t44b;Olr1452;Or2t44b", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "D3Z8M1", "url": "https://www.uniprot.org/uniprotkb/D3Z8M1" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "D3Z8M1", "url": "https://www.uniprot.org/uniprotkb/D3Z8M1" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "D3Z8M1", "url": "https://www.uniprot.org/uniprotkb/D3Z8M1" } ], "pmid": "" } ], "biological_process": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "D3Z8M1", "url": "https://www.uniprot.org/uniprotkb/D3Z8M1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3Z8M1-1" }, { "uniprot_canonical_ac": "D3Z8U5-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3Z8U5", "url": "https://www.uniprot.org/uniprotkb/D3Z8U5" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1013, "chemical_mass": 114586.0, "gene_names": "Tll1;Tll1;Tll", "protein_name": "Metalloendopeptidase", "disease": [ { "disease_id": "DOID:0110111", "name": "atrial heart septal defect 6", "description": "An atrial heart septal defect type 6 that has_material_basis_in heterozygous mutation in the TLL1 gene on chromosome 4q32.", "url": "https://disease-ontology.org/term/DOID:0110111", "evidence": [ { "id": "0110111", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110111" } ], "weight": 0.0 }, { "disease_id": "DOID:1682", "name": "congenital heart disease", "description": "A physical disorder that is characterized by problems with the heart's structure that are present at birth.", "url": "https://disease-ontology.org/term/DOID:1682", "evidence": [ { "id": "1682", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1682" } ], "weight": 0.0 }, { "disease_id": "DOID:3393", "name": "coronary artery disease", "description": "An artery disease that is characterized by plaque building up along the inner walls of the arteries of the heart resulting in a narrowing of the arteries and a reduced blood supply to the cardiac muscles.", "url": "https://disease-ontology.org/term/DOID:3393", "evidence": [ { "id": "3393", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3393" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "metalloendopeptidase activity", "id": "GO:0004222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004222", "evidence": [ { "database": "UniProtKB", "id": "D3Z8U5", "url": "https://www.uniprot.org/uniprotkb/D3Z8U5" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "D3Z8U5", "url": "https://www.uniprot.org/uniprotkb/D3Z8U5" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "D3Z8U5", "url": "https://www.uniprot.org/uniprotkb/D3Z8U5" } ], "pmid": "" }, { "name": "collagen binding", "id": "GO:0005518", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005518", "evidence": [ { "database": "UniProtKB", "id": "D3Z8U5", "url": "https://www.uniprot.org/uniprotkb/D3Z8U5" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "D3Z8U5", "url": "https://www.uniprot.org/uniprotkb/D3Z8U5" } ], "pmid": "" }, { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "D3Z8U5", "url": "https://www.uniprot.org/uniprotkb/D3Z8U5" } ], "pmid": "" } ], "biological_process": [ { "name": "protein processing", "id": "GO:0016485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016485", "evidence": [ { "database": "UniProtKB", "id": "D3Z8U5", "url": "https://www.uniprot.org/uniprotkb/D3Z8U5" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "D3Z8U5", "url": "https://www.uniprot.org/uniprotkb/D3Z8U5" } ], "pmid": "" }, { "name": "dorsal/ventral pattern formation", "id": "GO:0009953", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009953", "evidence": [ { "database": "UniProtKB", "id": "D3Z8U5", "url": "https://www.uniprot.org/uniprotkb/D3Z8U5" } ], "pmid": "" }, { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "D3Z8U5", "url": "https://www.uniprot.org/uniprotkb/D3Z8U5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "D3Z8U5-1", "start_pos": "382", "end_pos": "382", "site_lbl": "Thr382", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 382, "start_aa": "Thr", "end_pos": 382, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr382", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "D3Z8U5-1" }, { "uniprot_canonical_ac": "D3Z919-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3Z919", "url": "https://www.uniprot.org/uniprotkb/D3Z919" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 184, "chemical_mass": 21259.0, "gene_names": "LOC120103164;Ifna12l;LOC120103163", "protein_name": "", "disease": [], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "D3Z919", "url": "https://www.uniprot.org/uniprotkb/D3Z919" } ], "pmid": "" } ], "biological_process": [ { "name": "defense response to virus", "id": "GO:0051607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051607", "evidence": [ { "database": "UniProtKB", "id": "D3Z919", "url": "https://www.uniprot.org/uniprotkb/D3Z919" } ], "pmid": "" } ], "molecular_function": [ { "name": "cytokine activity", "id": "GO:0005125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005125", "evidence": [ { "database": "UniProtKB", "id": "D3Z919", "url": "https://www.uniprot.org/uniprotkb/D3Z919" } ], "pmid": "" }, { "name": "cytokine receptor binding", "id": "GO:0005126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005126", "evidence": [ { "database": "UniProtKB", "id": "D3Z919", "url": "https://www.uniprot.org/uniprotkb/D3Z919" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3Z919-1" }, { "uniprot_canonical_ac": "D3Z941-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3Z941", "url": "https://www.uniprot.org/uniprotkb/D3Z941" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 979, "chemical_mass": 110297.0, "gene_names": "Mars1;Mars", "protein_name": "Methionine--tRNA ligase, cytoplasmic", "disease": [ { "disease_id": "DOID:0061024", "name": "nonphotosensitive trichothiodystrophy 9", "description": "A nonphotosensitive trichothiodystrophy that is characterized by brittle hair and nails and scaly skin, accompanied by failure to thrive, microcephaly, and neuromotor developmental delay that has_material_basis_in homozygous mutation in the MARS1 gene on chromosome 12q13.", "url": "https://disease-ontology.org/term/DOID:0061024", "evidence": [ { "id": "0061024", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061024" } ], "weight": 0.0 }, { "disease_id": "DOID:0070454", "name": "hereditary spastic paraplegia 70", "description": "A hereditary spastic paraplegia characterized by infantile onset of motor delay and difficulties walking due to spasticity of the lower limbs that has_material_basis_in compound heterozygous mutation in the MARS1 gene on chromosome 12q13.3.", "url": "https://disease-ontology.org/term/DOID:0070454", "evidence": [ { "id": "0070454", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070454" } ], "weight": 0.0 }, { "disease_id": "DOID:0110173", "name": "Charcot-Marie-Tooth disease axonal type 2U", "description": "A Charcot-Marie-Tooth disease type 2 that has_material_basis_in heterozygous mutation in the MARS gene on chromosome 12q13.", "url": "https://disease-ontology.org/term/DOID:0110173", "evidence": [ { "id": "0110173", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110173" } ], "weight": 0.0 }, { "disease_id": "DOID:12120", "name": "pulmonary alveolar proteinosis", "description": "A lung disease that is characterized by abnormal accumulation of surfactant occurs within the alveoli, interfering with gas exchange.", "url": "https://disease-ontology.org/term/DOID:12120", "evidence": [ { "id": "12120", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12120" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "D3Z941", "url": "https://www.uniprot.org/uniprotkb/D3Z941" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "D3Z941", "url": "https://www.uniprot.org/uniprotkb/D3Z941" } ], "pmid": "" }, { "name": "methionine-tRNA ligase activity", "id": "GO:0004825", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004825", "evidence": [ { "database": "UniProtKB", "id": "D3Z941", "url": "https://www.uniprot.org/uniprotkb/D3Z941" } ], "pmid": "" }, { "name": "tRNA binding", "id": "GO:0000049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000049", "evidence": [ { "database": "UniProtKB", "id": "D3Z941", "url": "https://www.uniprot.org/uniprotkb/D3Z941" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "D3Z941", "url": "https://www.uniprot.org/uniprotkb/D3Z941" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "D3Z941", "url": "https://www.uniprot.org/uniprotkb/D3Z941" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "D3Z941", "url": "https://www.uniprot.org/uniprotkb/D3Z941" } ], "pmid": "" }, { "name": "aminoacyl-tRNA synthetase multienzyme complex", "id": "GO:0017101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017101", "evidence": [ { "database": "UniProtKB", "id": "D3Z941", "url": "https://www.uniprot.org/uniprotkb/D3Z941" } ], "pmid": "" } ], "biological_process": [ { "name": "rRNA transcription", "id": "GO:0009303", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009303", "evidence": [ { "database": "UniProtKB", "id": "D3Z941", "url": "https://www.uniprot.org/uniprotkb/D3Z941" } ], "pmid": "" }, { "name": "cellular response to epidermal growth factor stimulus", "id": "GO:0071364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071364", "evidence": [ { "database": "UniProtKB", "id": "D3Z941", "url": "https://www.uniprot.org/uniprotkb/D3Z941" } ], "pmid": "" }, { "name": "cellular response to platelet-derived growth factor stimulus", "id": "GO:0036120", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036120", "evidence": [ { "database": "UniProtKB", "id": "D3Z941", "url": "https://www.uniprot.org/uniprotkb/D3Z941" } ], "pmid": "" }, { "name": "positive regulation of transcription of nucleolar large rRNA by RNA polymerase I", "id": "GO:1901838", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901838", "evidence": [ { "database": "UniProtKB", "id": "D3Z941", "url": "https://www.uniprot.org/uniprotkb/D3Z941" } ], "pmid": "" }, { "name": "methionyl-tRNA aminoacylation", "id": "GO:0006431", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006431", "evidence": [ { "database": "UniProtKB", "id": "D3Z941", "url": "https://www.uniprot.org/uniprotkb/D3Z941" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3Z941-1" }, { "uniprot_canonical_ac": "D3Z984-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3Z984", "url": "https://www.uniprot.org/uniprotkb/D3Z984" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 314, "chemical_mass": 35402.0, "gene_names": "Or5g24;Olr447;Or5g24;ratchr3-68750625-68751569_ORF", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "D3Z984", "url": "https://www.uniprot.org/uniprotkb/D3Z984" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "D3Z984", "url": "https://www.uniprot.org/uniprotkb/D3Z984" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "D3Z984", "url": "https://www.uniprot.org/uniprotkb/D3Z984" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "D3Z984", "url": "https://www.uniprot.org/uniprotkb/D3Z984" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3Z984-1" }, { "uniprot_canonical_ac": "D3Z9I0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3Z9I0", "url": "https://www.uniprot.org/uniprotkb/D3Z9I0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 563, "chemical_mass": 62915.0, "gene_names": "Tmem145;Tmem145", "protein_name": "", "disease": [], "biological_process": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "D3Z9I0", "url": "https://www.uniprot.org/uniprotkb/D3Z9I0" } ], "pmid": "" }, { "name": "response to pheromone", "id": "GO:0019236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019236", "evidence": [ { "database": "UniProtKB", "id": "D3Z9I0", "url": "https://www.uniprot.org/uniprotkb/D3Z9I0" } ], "pmid": "" } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "D3Z9I0", "url": "https://www.uniprot.org/uniprotkb/D3Z9I0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "D3Z9I0-1", "start_pos": "530", "end_pos": "530", "site_lbl": "Thr530", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 530, "start_aa": "Thr", "end_pos": 530, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr530", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "D3Z9I0-1" }, { "uniprot_canonical_ac": "D3Z9P6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3Z9P6", "url": "https://www.uniprot.org/uniprotkb/D3Z9P6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 182, "chemical_mass": 20388.0, "gene_names": "Epgn;Epgn;RGD1560084", "protein_name": "Epigen", "disease": [], "biological_process": [ { "name": "angiogenesis", "id": "GO:0001525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001525", "evidence": [ { "database": "UniProtKB", "id": "D3Z9P6", "url": "https://www.uniprot.org/uniprotkb/D3Z9P6" } ], "pmid": "" }, { "name": "cell surface receptor signaling pathway", "id": "GO:0007166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007166", "evidence": [ { "database": "UniProtKB", "id": "D3Z9P6", "url": "https://www.uniprot.org/uniprotkb/D3Z9P6" } ], "pmid": "" }, { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "D3Z9P6", "url": "https://www.uniprot.org/uniprotkb/D3Z9P6" } ], "pmid": "" }, { "name": "positive regulation of MAPK cascade", "id": "GO:0043410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043410", "evidence": [ { "database": "UniProtKB", "id": "D3Z9P6", "url": "https://www.uniprot.org/uniprotkb/D3Z9P6" } ], "pmid": "" }, { "name": "MAPK cascade", "id": "GO:0000165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000165", "evidence": [ { "database": "UniProtKB", "id": "D3Z9P6", "url": "https://www.uniprot.org/uniprotkb/D3Z9P6" } ], "pmid": "" }, { "name": "epidermal growth factor receptor signaling pathway", "id": "GO:0007173", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007173", "evidence": [ { "database": "UniProtKB", "id": "D3Z9P6", "url": "https://www.uniprot.org/uniprotkb/D3Z9P6" } ], "pmid": "" }, { "name": "positive regulation of epithelial cell proliferation", "id": "GO:0050679", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050679", "evidence": [ { "database": "UniProtKB", "id": "D3Z9P6", "url": "https://www.uniprot.org/uniprotkb/D3Z9P6" } ], "pmid": "" }, { "name": "positive regulation of mitotic nuclear division", "id": "GO:0045840", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045840", "evidence": [ { "database": "UniProtKB", "id": "D3Z9P6", "url": "https://www.uniprot.org/uniprotkb/D3Z9P6" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "D3Z9P6", "url": "https://www.uniprot.org/uniprotkb/D3Z9P6" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "D3Z9P6", "url": "https://www.uniprot.org/uniprotkb/D3Z9P6" } ], "pmid": "" } ], "molecular_function": [ { "name": "epidermal growth factor receptor binding", "id": "GO:0005154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005154", "evidence": [ { "database": "UniProtKB", "id": "D3Z9P6", "url": "https://www.uniprot.org/uniprotkb/D3Z9P6" } ], "pmid": "" }, { "name": "growth factor activity", "id": "GO:0008083", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008083", "evidence": [ { "database": "UniProtKB", "id": "D3Z9P6", "url": "https://www.uniprot.org/uniprotkb/D3Z9P6" } ], "pmid": "" }, { "name": "receptor ligand activity", "id": "GO:0048018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048018", "evidence": [ { "database": "UniProtKB", "id": "D3Z9P6", "url": "https://www.uniprot.org/uniprotkb/D3Z9P6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3Z9P6-1" }, { "uniprot_canonical_ac": "D3Z9Y3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3Z9Y3", "url": "https://www.uniprot.org/uniprotkb/D3Z9Y3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 531, "chemical_mass": 59654.0, "gene_names": "Cerk;Cerk", "protein_name": "Ceramide kinase", "disease": [], "molecular_function": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "D3Z9Y3", "url": "https://www.uniprot.org/uniprotkb/D3Z9Y3" } ], "pmid": "" }, { "name": "ceramide kinase activity", "id": "GO:0001729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001729", "evidence": [ { "database": "UniProtKB", "id": "D3Z9Y3", "url": "https://www.uniprot.org/uniprotkb/D3Z9Y3" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "D3Z9Y3", "url": "https://www.uniprot.org/uniprotkb/D3Z9Y3" } ], "pmid": "" }, { "name": "kinase activity", "id": "GO:0016301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016301", "evidence": [ { "database": "UniProtKB", "id": "D3Z9Y3", "url": "https://www.uniprot.org/uniprotkb/D3Z9Y3" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "D3Z9Y3", "url": "https://www.uniprot.org/uniprotkb/D3Z9Y3" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "D3Z9Y3", "url": "https://www.uniprot.org/uniprotkb/D3Z9Y3" } ], "pmid": "" }, { "name": "cytoplasmic side of trans-Golgi network membrane", "id": "GO:0160281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160281", "evidence": [ { "database": "UniProtKB", "id": "D3Z9Y3", "url": "https://www.uniprot.org/uniprotkb/D3Z9Y3" } ], "pmid": "" } ], "biological_process": [ { "name": "ceramide metabolic process", "id": "GO:0006672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006672", "evidence": [ { "database": "UniProtKB", "id": "D3Z9Y3", "url": "https://www.uniprot.org/uniprotkb/D3Z9Y3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3Z9Y3-1" }, { "uniprot_canonical_ac": "D3ZA43-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZA43", "url": "https://www.uniprot.org/uniprotkb/D3ZA43" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 835, "chemical_mass": 96307.0, "gene_names": "Zfp780b;LOC134483039", "protein_name": "", "disease": [], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "D3ZA43", "url": "https://www.uniprot.org/uniprotkb/D3ZA43" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "D3ZA43", "url": "https://www.uniprot.org/uniprotkb/D3ZA43" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D3ZA43", "url": "https://www.uniprot.org/uniprotkb/D3ZA43" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "D3ZA43", "url": "https://www.uniprot.org/uniprotkb/D3ZA43" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "D3ZA43", "url": "https://www.uniprot.org/uniprotkb/D3ZA43" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZA43-1" }, { "uniprot_canonical_ac": "D3ZA45-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZA45", "url": "https://www.uniprot.org/uniprotkb/D3ZA45" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 479, "chemical_mass": 52634.0, "gene_names": "Atg13;Atg13;Harbi1l;Harbi1;RGD1310685", "protein_name": "Autophagy-related protein 13", "disease": [], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "D3ZA45", "url": "https://www.uniprot.org/uniprotkb/D3ZA45" } ], "pmid": "" }, { "name": "autophagosome", "id": "GO:0005776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005776", "evidence": [ { "database": "UniProtKB", "id": "D3ZA45", "url": "https://www.uniprot.org/uniprotkb/D3ZA45" } ], "pmid": "" }, { "name": "phagophore assembly site", "id": "GO:0000407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000407", "evidence": [ { "database": "UniProtKB", "id": "D3ZA45", "url": "https://www.uniprot.org/uniprotkb/D3ZA45" } ], "pmid": "" }, { "name": "Atg1/ULK1 kinase complex", "id": "GO:1990316", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990316", "evidence": [ { "database": "UniProtKB", "id": "D3ZA45", "url": "https://www.uniprot.org/uniprotkb/D3ZA45" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "D3ZA45", "url": "https://www.uniprot.org/uniprotkb/D3ZA45" } ], "pmid": "" }, { "name": "phagophore assembly site membrane", "id": "GO:0034045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034045", "evidence": [ { "database": "UniProtKB", "id": "D3ZA45", "url": "https://www.uniprot.org/uniprotkb/D3ZA45" } ], "pmid": "" }, { "name": "phosphatidylinositol 3-kinase complex, class III", "id": "GO:0035032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035032", "evidence": [ { "database": "UniProtKB", "id": "D3ZA45", "url": "https://www.uniprot.org/uniprotkb/D3ZA45" } ], "pmid": "" } ], "biological_process": [ { "name": "protein localization to phagophore assembly site", "id": "GO:0034497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034497", "evidence": [ { "database": "UniProtKB", "id": "D3ZA45", "url": "https://www.uniprot.org/uniprotkb/D3ZA45" } ], "pmid": "" }, { "name": "mitophagy", "id": "GO:0000423", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000423", "evidence": [ { "database": "UniProtKB", "id": "D3ZA45", "url": "https://www.uniprot.org/uniprotkb/D3ZA45" } ], "pmid": "" }, { "name": "piecemeal microautophagy of the nucleus", "id": "GO:0034727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034727", "evidence": [ { "database": "UniProtKB", "id": "D3ZA45", "url": "https://www.uniprot.org/uniprotkb/D3ZA45" } ], "pmid": "" }, { "name": "autophagosome assembly", "id": "GO:0000045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000045", "evidence": [ { "database": "UniProtKB", "id": "D3ZA45", "url": "https://www.uniprot.org/uniprotkb/D3ZA45" } ], "pmid": "" }, { "name": "negative regulation of cell population proliferation", "id": "GO:0008285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008285", "evidence": [ { "database": "UniProtKB", "id": "D3ZA45", "url": "https://www.uniprot.org/uniprotkb/D3ZA45" } ], "pmid": "" }, { "name": "positive regulation of autophagy", "id": "GO:0010508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010508", "evidence": [ { "database": "UniProtKB", "id": "D3ZA45", "url": "https://www.uniprot.org/uniprotkb/D3ZA45" } ], "pmid": "" }, { "name": "response to mitochondrial depolarisation", "id": "GO:0098780", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098780", "evidence": [ { "database": "UniProtKB", "id": "D3ZA45", "url": "https://www.uniprot.org/uniprotkb/D3ZA45" } ], "pmid": "" }, { "name": "regulation of protein lipidation", "id": "GO:1903059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903059", "evidence": [ { "database": "UniProtKB", "id": "D3ZA45", "url": "https://www.uniprot.org/uniprotkb/D3ZA45" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein kinase regulator activity", "id": "GO:0019887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019887", "evidence": [ { "database": "UniProtKB", "id": "D3ZA45", "url": "https://www.uniprot.org/uniprotkb/D3ZA45" } ], "pmid": "" }, { "name": "kinase activator activity", "id": "GO:0019209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019209", "evidence": [ { "database": "UniProtKB", "id": "D3ZA45", "url": "https://www.uniprot.org/uniprotkb/D3ZA45" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "D3ZA45", "url": "https://www.uniprot.org/uniprotkb/D3ZA45" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "D3ZA45-1", "start_pos": "135", "end_pos": "135", "site_lbl": "Thr135", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 135, "start_aa": "Thr", "end_pos": 135, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr135", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "D3ZA45-1" }, { "uniprot_canonical_ac": "D3ZAG3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZAG3", "url": "https://www.uniprot.org/uniprotkb/D3ZAG3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 646, "chemical_mass": 73600.0, "gene_names": "Map9;Map9;Mtap9;RGD1560368", "protein_name": "", "disease": [], "biological_process": [ { "name": "regulation of mitotic centrosome separation", "id": "GO:0046602", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046602", "evidence": [ { "database": "UniProtKB", "id": "D3ZAG3", "url": "https://www.uniprot.org/uniprotkb/D3ZAG3" } ], "pmid": "" }, { "name": "mitotic spindle assembly", "id": "GO:0090307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090307", "evidence": [ { "database": "UniProtKB", "id": "D3ZAG3", "url": "https://www.uniprot.org/uniprotkb/D3ZAG3" } ], "pmid": "" }, { "name": "mitotic cytokinesis", "id": "GO:0000281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000281", "evidence": [ { "database": "UniProtKB", "id": "D3ZAG3", "url": "https://www.uniprot.org/uniprotkb/D3ZAG3" } ], "pmid": "" }, { "name": "regulation of mitotic spindle organization", "id": "GO:0060236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060236", "evidence": [ { "database": "UniProtKB", "id": "D3ZAG3", "url": "https://www.uniprot.org/uniprotkb/D3ZAG3" } ], "pmid": "" }, { "name": "regulation of mitotic cytokinesis", "id": "GO:1902412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902412", "evidence": [ { "database": "UniProtKB", "id": "D3ZAG3", "url": "https://www.uniprot.org/uniprotkb/D3ZAG3" } ], "pmid": "" } ], "cellular_component": [ { "name": "astral microtubule", "id": "GO:0000235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000235", "evidence": [ { "database": "UniProtKB", "id": "D3ZAG3", "url": "https://www.uniprot.org/uniprotkb/D3ZAG3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "D3ZAG3", "url": "https://www.uniprot.org/uniprotkb/D3ZAG3" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "D3ZAG3", "url": "https://www.uniprot.org/uniprotkb/D3ZAG3" } ], "pmid": "" }, { "name": "spindle midzone", "id": "GO:0051233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051233", "evidence": [ { "database": "UniProtKB", "id": "D3ZAG3", "url": "https://www.uniprot.org/uniprotkb/D3ZAG3" } ], "pmid": "" }, { "name": "microtubule cytoskeleton", "id": "GO:0015630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015630", "evidence": [ { "database": "UniProtKB", "id": "D3ZAG3", "url": "https://www.uniprot.org/uniprotkb/D3ZAG3" } ], "pmid": "" }, { "name": "mitotic spindle", "id": "GO:0072686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072686", "evidence": [ { "database": "UniProtKB", "id": "D3ZAG3", "url": "https://www.uniprot.org/uniprotkb/D3ZAG3" } ], "pmid": "" }, { "name": "mitotic spindle midzone", "id": "GO:1990023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990023", "evidence": [ { "database": "UniProtKB", "id": "D3ZAG3", "url": "https://www.uniprot.org/uniprotkb/D3ZAG3" } ], "pmid": "" }, { "name": "aster", "id": "GO:0005818", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005818", "evidence": [ { "database": "UniProtKB", "id": "D3ZAG3", "url": "https://www.uniprot.org/uniprotkb/D3ZAG3" } ], "pmid": "" } ], "molecular_function": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "D3ZAG3", "url": "https://www.uniprot.org/uniprotkb/D3ZAG3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "D3ZAG3-1", "start_pos": "211", "end_pos": "211", "site_lbl": "Thr211", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 211, "start_aa": "Thr", "end_pos": 211, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr211", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "D3ZAG3-1" }, { "uniprot_canonical_ac": "D3ZAI1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZAI1", "url": "https://www.uniprot.org/uniprotkb/D3ZAI1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 314, "chemical_mass": 35570.0, "gene_names": "Or2aj4b;Or2aj4;Olr1565;Or2aj4b", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "D3ZAI1", "url": "https://www.uniprot.org/uniprotkb/D3ZAI1" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "D3ZAI1", "url": "https://www.uniprot.org/uniprotkb/D3ZAI1" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "D3ZAI1", "url": "https://www.uniprot.org/uniprotkb/D3ZAI1" } ], "pmid": "" } ], "biological_process": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "D3ZAI1", "url": "https://www.uniprot.org/uniprotkb/D3ZAI1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZAI1-1" }, { "uniprot_canonical_ac": "D3ZAJ3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZAJ3", "url": "https://www.uniprot.org/uniprotkb/D3ZAJ3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 313, "chemical_mass": 35294.0, "gene_names": "Or52e5;Olr186;Or52e5", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "D3ZAJ3", "url": "https://www.uniprot.org/uniprotkb/D3ZAJ3" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "D3ZAJ3", "url": "https://www.uniprot.org/uniprotkb/D3ZAJ3" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "D3ZAJ3", "url": "https://www.uniprot.org/uniprotkb/D3ZAJ3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZAJ3-1" }, { "uniprot_canonical_ac": "D3ZAN2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZAN2", "url": "https://www.uniprot.org/uniprotkb/D3ZAN2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1310, "chemical_mass": 143192.0, "gene_names": "Cdhr2;Cdhr2;Pcdh24;RGD1560576", "protein_name": "Cadherin-related family member 2", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "D3ZAN2", "url": "https://www.uniprot.org/uniprotkb/D3ZAN2" } ], "pmid": "" }, { "name": "brush border", "id": "GO:0005903", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005903", "evidence": [ { "database": "UniProtKB", "id": "D3ZAN2", "url": "https://www.uniprot.org/uniprotkb/D3ZAN2" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "D3ZAN2", "url": "https://www.uniprot.org/uniprotkb/D3ZAN2" } ], "pmid": "" }, { "name": "brush border membrane", "id": "GO:0031526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031526", "evidence": [ { "database": "UniProtKB", "id": "D3ZAN2", "url": "https://www.uniprot.org/uniprotkb/D3ZAN2" } ], "pmid": "" }, { "name": "microvillus", "id": "GO:0005902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005902", "evidence": [ { "database": "UniProtKB", "id": "D3ZAN2", "url": "https://www.uniprot.org/uniprotkb/D3ZAN2" } ], "pmid": "" }, { "name": "microvillus membrane", "id": "GO:0031528", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031528", "evidence": [ { "database": "UniProtKB", "id": "D3ZAN2", "url": "https://www.uniprot.org/uniprotkb/D3ZAN2" } ], "pmid": "" }, { "name": "anchoring junction", "id": "GO:0070161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070161", "evidence": [ { "database": "UniProtKB", "id": "D3ZAN2", "url": "https://www.uniprot.org/uniprotkb/D3ZAN2" } ], "pmid": "" } ], "biological_process": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "D3ZAN2", "url": "https://www.uniprot.org/uniprotkb/D3ZAN2" } ], "pmid": "" }, { "name": "epithelial cell differentiation", "id": "GO:0030855", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030855", "evidence": [ { "database": "UniProtKB", "id": "D3ZAN2", "url": "https://www.uniprot.org/uniprotkb/D3ZAN2" } ], "pmid": "" }, { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "D3ZAN2", "url": "https://www.uniprot.org/uniprotkb/D3ZAN2" } ], "pmid": "" }, { "name": "brush border assembly", "id": "GO:1904970", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904970", "evidence": [ { "database": "UniProtKB", "id": "D3ZAN2", "url": "https://www.uniprot.org/uniprotkb/D3ZAN2" } ], "pmid": "" }, { "name": "regulation of microvillus length", "id": "GO:0032532", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032532", "evidence": [ { "database": "UniProtKB", "id": "D3ZAN2", "url": "https://www.uniprot.org/uniprotkb/D3ZAN2" } ], "pmid": "" }, { "name": "negative regulation of cell growth involved in contact inhibition", "id": "GO:0060243", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060243", "evidence": [ { "database": "UniProtKB", "id": "D3ZAN2", "url": "https://www.uniprot.org/uniprotkb/D3ZAN2" } ], "pmid": "" }, { "name": "intermicrovillar adhesion", "id": "GO:0090675", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090675", "evidence": [ { "database": "UniProtKB", "id": "D3ZAN2", "url": "https://www.uniprot.org/uniprotkb/D3ZAN2" } ], "pmid": "" }, { "name": "cell-cell adhesion mediated by cadherin", "id": "GO:0044331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044331", "evidence": [ { "database": "UniProtKB", "id": "D3ZAN2", "url": "https://www.uniprot.org/uniprotkb/D3ZAN2" } ], "pmid": "" } ], "molecular_function": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "D3ZAN2", "url": "https://www.uniprot.org/uniprotkb/D3ZAN2" } ], "pmid": "" }, { "name": "cell adhesion molecule binding", "id": "GO:0050839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050839", "evidence": [ { "database": "UniProtKB", "id": "D3ZAN2", "url": "https://www.uniprot.org/uniprotkb/D3ZAN2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZAN2-1" }, { "uniprot_canonical_ac": "D3ZAP7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZAP7", "url": "https://www.uniprot.org/uniprotkb/D3ZAP7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 2985, "chemical_mass": 333863.0, "gene_names": "Chd7;Chd7", "protein_name": "ATP-dependent chromatin remodeler CHD7", "disease": [ { "disease_id": "DOID:0050834", "name": "CHARGE syndrome", "description": "A syndrome that is characterized by a pattern of congenital anomalies including choanal atresia and malformations of the heart, inner ear, and retina.", "url": "https://disease-ontology.org/term/DOID:0050834", "evidence": [ { "id": "0050834", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050834" } ], "weight": 0.0 }, { "disease_id": "DOID:0060041", "name": "autism spectrum disorder", "description": "A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior.", "url": "https://disease-ontology.org/term/DOID:0060041", "evidence": [ { "id": "0060041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060041" } ], "weight": 0.0 }, { "disease_id": "DOID:0090084", "name": "hypogonadotropic hypogonadism 5 with or without anosmia", "description": "A hypogonadotropic hypogonadism that is characterized by autosomal dominant inheritance and has_material_basis_in heterozygous mutation in the CHD7 gene on chromosome 8q12.", "url": "https://disease-ontology.org/term/DOID:0090084", "evidence": [ { "id": "0090084", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0090084" } ], "weight": 0.0 }, { "disease_id": "DOID:1682", "name": "congenital heart disease", "description": "A physical disorder that is characterized by problems with the heart's structure that are present at birth.", "url": "https://disease-ontology.org/term/DOID:1682", "evidence": [ { "id": "1682", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1682" } ], "weight": 0.0 } ], "biological_process": [ { "name": "right ventricular compact myocardium morphogenesis", "id": "GO:0003226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003226", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP7", "url": "https://www.uniprot.org/uniprotkb/D3ZAP7" } ], "pmid": "" }, { "name": "cranial nerve development", "id": "GO:0021545", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021545", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP7", "url": "https://www.uniprot.org/uniprotkb/D3ZAP7" } ], "pmid": "" }, { "name": "olfactory nerve development", "id": "GO:0021553", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021553", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP7", "url": "https://www.uniprot.org/uniprotkb/D3ZAP7" } ], "pmid": "" }, { "name": "female genitalia development", "id": "GO:0030540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030540", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP7", "url": "https://www.uniprot.org/uniprotkb/D3ZAP7" } ], "pmid": "" }, { "name": "atrioventricular canal development", "id": "GO:0036302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036302", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP7", "url": "https://www.uniprot.org/uniprotkb/D3ZAP7" } ], "pmid": "" }, { "name": "olfactory behavior", "id": "GO:0042048", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042048", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP7", "url": "https://www.uniprot.org/uniprotkb/D3ZAP7" } ], "pmid": "" }, { "name": "nose development", "id": "GO:0043584", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043584", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP7", "url": "https://www.uniprot.org/uniprotkb/D3ZAP7" } ], "pmid": "" }, { "name": "semicircular canal morphogenesis", "id": "GO:0048752", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048752", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP7", "url": "https://www.uniprot.org/uniprotkb/D3ZAP7" } ], "pmid": "" }, { "name": "genitalia development", "id": "GO:0048806", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048806", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP7", "url": "https://www.uniprot.org/uniprotkb/D3ZAP7" } ], "pmid": "" }, { "name": "regulation of growth hormone secretion", "id": "GO:0060123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060123", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP7", "url": "https://www.uniprot.org/uniprotkb/D3ZAP7" } ], "pmid": "" }, { "name": "innervation", "id": "GO:0060384", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060384", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP7", "url": "https://www.uniprot.org/uniprotkb/D3ZAP7" } ], "pmid": "" }, { "name": "epithelium development", "id": "GO:0060429", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060429", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP7", "url": "https://www.uniprot.org/uniprotkb/D3ZAP7" } ], "pmid": "" }, { "name": "in utero embryonic development", "id": "GO:0001701", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001701", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP7", "url": "https://www.uniprot.org/uniprotkb/D3ZAP7" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP7", "url": "https://www.uniprot.org/uniprotkb/D3ZAP7" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP7", "url": "https://www.uniprot.org/uniprotkb/D3ZAP7" } ], "pmid": "" }, { "name": "locomotory behavior", "id": "GO:0007626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007626", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP7", "url": "https://www.uniprot.org/uniprotkb/D3ZAP7" } ], "pmid": "" }, { "name": "inner ear morphogenesis", "id": "GO:0042472", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042472", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP7", "url": "https://www.uniprot.org/uniprotkb/D3ZAP7" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP7", "url": "https://www.uniprot.org/uniprotkb/D3ZAP7" } ], "pmid": "" }, { "name": "cognition", "id": "GO:0050890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050890", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP7", "url": "https://www.uniprot.org/uniprotkb/D3ZAP7" } ], "pmid": "" }, { "name": "blood vessel remodeling", "id": "GO:0001974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001974", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP7", "url": "https://www.uniprot.org/uniprotkb/D3ZAP7" } ], "pmid": "" }, { "name": "blood circulation", "id": "GO:0008015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008015", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP7", "url": "https://www.uniprot.org/uniprotkb/D3ZAP7" } ], "pmid": "" }, { "name": "central nervous system development", "id": "GO:0007417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007417", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP7", "url": "https://www.uniprot.org/uniprotkb/D3ZAP7" } ], "pmid": "" }, { "name": "response to bacterium", "id": "GO:0009617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009617", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP7", "url": "https://www.uniprot.org/uniprotkb/D3ZAP7" } ], "pmid": "" }, { "name": "skeletal system development", "id": "GO:0001501", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001501", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP7", "url": "https://www.uniprot.org/uniprotkb/D3ZAP7" } ], "pmid": "" }, { "name": "retina development in camera-type eye", "id": "GO:0060041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060041", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP7", "url": "https://www.uniprot.org/uniprotkb/D3ZAP7" } ], "pmid": "" }, { "name": "blood vessel development", "id": "GO:0001568", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001568", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP7", "url": "https://www.uniprot.org/uniprotkb/D3ZAP7" } ], "pmid": "" }, { "name": "heart morphogenesis", "id": "GO:0003007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003007", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP7", "url": "https://www.uniprot.org/uniprotkb/D3ZAP7" } ], "pmid": "" }, { "name": "adult walking behavior", "id": "GO:0007628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007628", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP7", "url": "https://www.uniprot.org/uniprotkb/D3ZAP7" } ], "pmid": "" }, { "name": "face development", "id": "GO:0060324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060324", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP7", "url": "https://www.uniprot.org/uniprotkb/D3ZAP7" } ], "pmid": "" }, { "name": "sensory perception of sound", "id": "GO:0007605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007605", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP7", "url": "https://www.uniprot.org/uniprotkb/D3ZAP7" } ], "pmid": "" }, { "name": "aorta development", "id": "GO:0035904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035904", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP7", "url": "https://www.uniprot.org/uniprotkb/D3ZAP7" } ], "pmid": "" }, { "name": "roof of mouth development", "id": "GO:0060021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060021", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP7", "url": "https://www.uniprot.org/uniprotkb/D3ZAP7" } ], "pmid": "" }, { "name": "limb development", "id": "GO:0060173", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060173", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP7", "url": "https://www.uniprot.org/uniprotkb/D3ZAP7" } ], "pmid": "" }, { "name": "embryonic hindlimb morphogenesis", "id": "GO:0035116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035116", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP7", "url": "https://www.uniprot.org/uniprotkb/D3ZAP7" } ], "pmid": "" }, { "name": "regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum", "id": "GO:0010880", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010880", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP7", "url": "https://www.uniprot.org/uniprotkb/D3ZAP7" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP7", "url": "https://www.uniprot.org/uniprotkb/D3ZAP7" } ], "pmid": "" }, { "name": "adult heart development", "id": "GO:0007512", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007512", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP7", "url": "https://www.uniprot.org/uniprotkb/D3ZAP7" } ], "pmid": "" }, { "name": "aorta morphogenesis", "id": "GO:0035909", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035909", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP7", "url": "https://www.uniprot.org/uniprotkb/D3ZAP7" } ], "pmid": "" }, { "name": "artery morphogenesis", "id": "GO:0048844", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048844", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP7", "url": "https://www.uniprot.org/uniprotkb/D3ZAP7" } ], "pmid": "" }, { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP7", "url": "https://www.uniprot.org/uniprotkb/D3ZAP7" } ], "pmid": "" }, { "name": "regulation of neurogenesis", "id": "GO:0050767", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050767", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP7", "url": "https://www.uniprot.org/uniprotkb/D3ZAP7" } ], "pmid": "" }, { "name": "positive regulation of multicellular organism growth", "id": "GO:0040018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040018", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP7", "url": "https://www.uniprot.org/uniprotkb/D3ZAP7" } ], "pmid": "" }, { "name": "T cell differentiation", "id": "GO:0030217", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030217", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP7", "url": "https://www.uniprot.org/uniprotkb/D3ZAP7" } ], "pmid": "" }, { "name": "camera-type eye development", "id": "GO:0043010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043010", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP7", "url": "https://www.uniprot.org/uniprotkb/D3ZAP7" } ], "pmid": "" }, { "name": "cardiac septum morphogenesis", "id": "GO:0060411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060411", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP7", "url": "https://www.uniprot.org/uniprotkb/D3ZAP7" } ], "pmid": "" }, { "name": "ventricular trabecula myocardium morphogenesis", "id": "GO:0003222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003222", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP7", "url": "https://www.uniprot.org/uniprotkb/D3ZAP7" } ], "pmid": "" }, { "name": "chordate embryonic development", "id": "GO:0043009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043009", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP7", "url": "https://www.uniprot.org/uniprotkb/D3ZAP7" } ], "pmid": "" }, { "name": "olfactory bulb development", "id": "GO:0021772", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021772", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP7", "url": "https://www.uniprot.org/uniprotkb/D3ZAP7" } ], "pmid": "" }, { "name": "tissue remodeling", "id": "GO:0048771", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048771", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP7", "url": "https://www.uniprot.org/uniprotkb/D3ZAP7" } ], "pmid": "" }, { "name": "ear morphogenesis", "id": "GO:0042471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042471", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP7", "url": "https://www.uniprot.org/uniprotkb/D3ZAP7" } ], "pmid": "" }, { "name": "secondary palate development", "id": "GO:0062009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0062009", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP7", "url": "https://www.uniprot.org/uniprotkb/D3ZAP7" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP7", "url": "https://www.uniprot.org/uniprotkb/D3ZAP7" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP7", "url": "https://www.uniprot.org/uniprotkb/D3ZAP7" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP7", "url": "https://www.uniprot.org/uniprotkb/D3ZAP7" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP7", "url": "https://www.uniprot.org/uniprotkb/D3ZAP7" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP7", "url": "https://www.uniprot.org/uniprotkb/D3ZAP7" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP7", "url": "https://www.uniprot.org/uniprotkb/D3ZAP7" } ], "pmid": "" }, { "name": "promoter-specific chromatin binding", "id": "GO:1990841", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990841", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP7", "url": "https://www.uniprot.org/uniprotkb/D3ZAP7" } ], "pmid": "" }, { "name": "ATP-dependent chromatin remodeler activity", "id": "GO:0140658", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140658", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP7", "url": "https://www.uniprot.org/uniprotkb/D3ZAP7" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP7", "url": "https://www.uniprot.org/uniprotkb/D3ZAP7" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP7", "url": "https://www.uniprot.org/uniprotkb/D3ZAP7" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP7", "url": "https://www.uniprot.org/uniprotkb/D3ZAP7" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP7", "url": "https://www.uniprot.org/uniprotkb/D3ZAP7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZAP7-1" }, { "uniprot_canonical_ac": "D3ZAP9-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZAP9", "url": "https://www.uniprot.org/uniprotkb/D3ZAP9" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 351, "chemical_mass": 38066.0, "gene_names": "Gpd1l;Gpd1l1;Gpd1l;RGD1560123", "protein_name": "Glycerol-3-phosphate dehydrogenase [NAD(+)]", "disease": [ { "disease_id": "DOID:0110219", "name": "Brugada syndrome 2", "description": "A Brugada syndrome that has_material_basis_in heterozygous mutation in the GPD1L gene on chromosome 3p22.", "url": "https://disease-ontology.org/term/DOID:0110219", "evidence": [ { "id": "0110219", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110219" } ], "weight": 0.0 } ], "biological_process": [ { "name": "regulation of ventricular cardiac muscle cell membrane depolarization", "id": "GO:0060373", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060373", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP9", "url": "https://www.uniprot.org/uniprotkb/D3ZAP9" } ], "pmid": "" }, { "name": "positive regulation of protein localization to cell surface", "id": "GO:2000010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000010", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP9", "url": "https://www.uniprot.org/uniprotkb/D3ZAP9" } ], "pmid": "" }, { "name": "carbohydrate metabolic process", "id": "GO:0005975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005975", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP9", "url": "https://www.uniprot.org/uniprotkb/D3ZAP9" } ], "pmid": "" }, { "name": "NAD+ metabolic process", "id": "GO:0019674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019674", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP9", "url": "https://www.uniprot.org/uniprotkb/D3ZAP9" } ], "pmid": "" }, { "name": "positive regulation of sodium ion transport", "id": "GO:0010765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010765", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP9", "url": "https://www.uniprot.org/uniprotkb/D3ZAP9" } ], "pmid": "" }, { "name": "regulation of heart rate", "id": "GO:0002027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002027", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP9", "url": "https://www.uniprot.org/uniprotkb/D3ZAP9" } ], "pmid": "" }, { "name": "ventricular cardiac muscle cell action potential", "id": "GO:0086005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0086005", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP9", "url": "https://www.uniprot.org/uniprotkb/D3ZAP9" } ], "pmid": "" }, { "name": "glycerol-3-phosphate catabolic process", "id": "GO:0046168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046168", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP9", "url": "https://www.uniprot.org/uniprotkb/D3ZAP9" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP9", "url": "https://www.uniprot.org/uniprotkb/D3ZAP9" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP9", "url": "https://www.uniprot.org/uniprotkb/D3ZAP9" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP9", "url": "https://www.uniprot.org/uniprotkb/D3ZAP9" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP9", "url": "https://www.uniprot.org/uniprotkb/D3ZAP9" } ], "pmid": "" }, { "name": "sodium channel regulator activity", "id": "GO:0017080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017080", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP9", "url": "https://www.uniprot.org/uniprotkb/D3ZAP9" } ], "pmid": "" }, { "name": "transmembrane transporter binding", "id": "GO:0044325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044325", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP9", "url": "https://www.uniprot.org/uniprotkb/D3ZAP9" } ], "pmid": "" }, { "name": "NAD binding", "id": "GO:0051287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051287", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP9", "url": "https://www.uniprot.org/uniprotkb/D3ZAP9" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor", "id": "GO:0016616", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016616", "evidence": [ { "database": "UniProtKB", "id": "D3ZAP9", "url": "https://www.uniprot.org/uniprotkb/D3ZAP9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZAP9-1" }, { "uniprot_canonical_ac": "D3ZAR0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZAR0", "url": "https://www.uniprot.org/uniprotkb/D3ZAR0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 273, "chemical_mass": 31169.0, "gene_names": "Ccdc3;Ccdc3;RGD1559473", "protein_name": "", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "D3ZAR0", "url": "https://www.uniprot.org/uniprotkb/D3ZAR0" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "D3ZAR0", "url": "https://www.uniprot.org/uniprotkb/D3ZAR0" } ], "pmid": "" } ], "biological_process": [ { "name": "fatty acid metabolic process", "id": "GO:0006631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006631", "evidence": [ { "database": "UniProtKB", "id": "D3ZAR0", "url": "https://www.uniprot.org/uniprotkb/D3ZAR0" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "D3ZAR0", "url": "https://www.uniprot.org/uniprotkb/D3ZAR0" } ], "pmid": "" }, { "name": "cholesterol metabolic process", "id": "GO:0008203", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008203", "evidence": [ { "database": "UniProtKB", "id": "D3ZAR0", "url": "https://www.uniprot.org/uniprotkb/D3ZAR0" } ], "pmid": "" }, { "name": "negative regulation of gene expression", "id": "GO:0010629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010629", "evidence": [ { "database": "UniProtKB", "id": "D3ZAR0", "url": "https://www.uniprot.org/uniprotkb/D3ZAR0" } ], "pmid": "" }, { "name": "positive regulation of fat cell differentiation", "id": "GO:0045600", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045600", "evidence": [ { "database": "UniProtKB", "id": "D3ZAR0", "url": "https://www.uniprot.org/uniprotkb/D3ZAR0" } ], "pmid": "" }, { "name": "positive regulation of lipid biosynthetic process", "id": "GO:0046889", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046889", "evidence": [ { "database": "UniProtKB", "id": "D3ZAR0", "url": "https://www.uniprot.org/uniprotkb/D3ZAR0" } ], "pmid": "" }, { "name": "blood vessel development", "id": "GO:0001568", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001568", "evidence": [ { "database": "UniProtKB", "id": "D3ZAR0", "url": "https://www.uniprot.org/uniprotkb/D3ZAR0" } ], "pmid": "" }, { "name": "negative regulation of tumor necrosis factor-mediated signaling pathway", "id": "GO:0010804", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010804", "evidence": [ { "database": "UniProtKB", "id": "D3ZAR0", "url": "https://www.uniprot.org/uniprotkb/D3ZAR0" } ], "pmid": "" }, { "name": "calcium ion homeostasis", "id": "GO:0055074", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055074", "evidence": [ { "database": "UniProtKB", "id": "D3ZAR0", "url": "https://www.uniprot.org/uniprotkb/D3ZAR0" } ], "pmid": "" }, { "name": "negative regulation of lipid metabolic process", "id": "GO:0045833", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045833", "evidence": [ { "database": "UniProtKB", "id": "D3ZAR0", "url": "https://www.uniprot.org/uniprotkb/D3ZAR0" } ], "pmid": "" }, { "name": "negative regulation of lipid biosynthetic process", "id": "GO:0051055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051055", "evidence": [ { "database": "UniProtKB", "id": "D3ZAR0", "url": "https://www.uniprot.org/uniprotkb/D3ZAR0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZAR0-1" }, { "uniprot_canonical_ac": "D3ZAU0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZAU0", "url": "https://www.uniprot.org/uniprotkb/D3ZAU0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 3925, "chemical_mass": 423795.0, "gene_names": "Muc5b;Muc5b;RGD1561983", "protein_name": "Mucin-2", "disease": [ { "disease_id": "DOID:0050127", "name": "sinusitis", "description": "A paranasal sinus disease involving inflammation of the paranasal sinuses resulting from bacterial, fungal, viral infection, allergic or autoimmune issues. Symptoms can include fever, weakness, fatigue, cough and congestion. There may also be mucus drainage in the back of the throat, called postnasal drip.", "url": "https://disease-ontology.org/term/DOID:0050127", "evidence": [ { "id": "0050127", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050127" } ], "weight": 0.0 }, { "disease_id": "DOID:0060971", "name": "interstitial lung disease 2", "description": "An interstitial lung disease pulmonary fibrosis that is characterized by scarring of the lung and that has_material_basis_in heterozygous mutation in the SFTPA2 gene on chromosome 10q22.", "url": "https://disease-ontology.org/term/DOID:0060971", "evidence": [ { "id": "0060971", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060971" } ], "weight": 0.0 }, { "disease_id": "DOID:10754", "name": "otitis media", "description": "A otitis which involves inflammation of the middle ear.", "url": "https://disease-ontology.org/term/DOID:10754", "evidence": [ { "id": "10754", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10754" } ], "weight": 0.0 }, { "disease_id": "DOID:11054", "name": "urinary bladder cancer", "description": "An urinary system cancer that results_in malignant growth located_in the urinary bladder.", "url": "https://disease-ontology.org/term/DOID:11054", "evidence": [ { "id": "11054", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11054" } ], "weight": 0.0 }, { "disease_id": "DOID:1485", "name": "cystic fibrosis", "description": "A syndrome that is characterized by the buildup of thick, sticky mucus that can damage many organs.", "url": "https://disease-ontology.org/term/DOID:1485", "evidence": [ { "id": "1485", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1485" } ], "weight": 0.0 }, { "disease_id": "DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.", "url": "https://disease-ontology.org/term/DOID:2841", "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ], "weight": 0.0 }, { "disease_id": "DOID:2942", "name": "bronchiolitis", "description": "A lung disease that is an inflammation of the bronchioles, the smallest air passages of the lungs. It is caused by viruses and bacteria. The disease has_symptom cough, has_symptom wheezing, has_symptom shortness of breath, has_symptom fever, has_symptom nasal flaring in infants and has_symptom bluish skin due to lack of oxygen.", "url": "https://disease-ontology.org/term/DOID:2942", "evidence": [ { "id": "2942", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2942" } ], "weight": 0.0 }, { "disease_id": "DOID:3083", "name": "chronic obstructive pulmonary disease", "description": "An obstructive lung disease that is a chronic and progressive disorder of small airways in the lungs and that is characterized by irreversible airflow obstruction, typically identified by reductions in quantitative spirometric indices, induced forced expiratory volume at 1 second (FEV1) and the ratio of FEV1 to forced vital capacity (less than 0.7 is diagnostic of COPD). Lung volume is increased and pulmonary hypertension may occur. The pathologic changes result in the disruption of the airflow in the bronchial airways. Signs and symptoms include shortness of breath, wheezing, productive cough and chest tightness. COPD is a consequence (an end result) of chronic bronchitis, emphysema or both.", "url": "https://disease-ontology.org/term/DOID:3083", "evidence": [ { "id": "3083", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3083" } ], "weight": 0.0 }, { "disease_id": "DOID:3587", "name": "pancreatic ductal carcinoma", "description": "A pancreatic carcinoma located_in the pancreatic duct.", "url": "https://disease-ontology.org/term/DOID:3587", "evidence": [ { "id": "3587", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3587" } ], "weight": 0.0 }, { "disease_id": "DOID:4947", "name": "cholangiocarcinoma", "description": "A bile duct adenocarcinoma that has_material_basis_in bile duct epithelial cells.", "url": "https://disease-ontology.org/term/DOID:4947", "evidence": [ { "id": "4947", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4947" } ], "weight": 0.0 }, { "disease_id": "DOID:9261", "name": "nasopharynx carcinoma", "description": "A pharynx cancer that is located in the nasopharynx, the uppermost region of the pharynx or throat, where the nasal passages and auditory tubes join the remainder of the upper respiratory tract.", "url": "https://disease-ontology.org/term/DOID:9261", "evidence": [ { "id": "9261", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9261" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "D3ZAU0", "url": "https://www.uniprot.org/uniprotkb/D3ZAU0" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "D3ZAU0", "url": "https://www.uniprot.org/uniprotkb/D3ZAU0" } ], "pmid": "" } ], "biological_process": [ { "name": "defense response to bacterium", "id": "GO:0042742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042742", "evidence": [ { "database": "UniProtKB", "id": "D3ZAU0", "url": "https://www.uniprot.org/uniprotkb/D3ZAU0" } ], "pmid": "" }, { "name": "negative regulation of single-species biofilm formation in or on host organism", "id": "GO:1900229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900229", "evidence": [ { "database": "UniProtKB", "id": "D3ZAU0", "url": "https://www.uniprot.org/uniprotkb/D3ZAU0" } ], "pmid": "" }, { "name": "regulation of macrophage activation", "id": "GO:0043030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043030", "evidence": [ { "database": "UniProtKB", "id": "D3ZAU0", "url": "https://www.uniprot.org/uniprotkb/D3ZAU0" } ], "pmid": "" } ], "molecular_function": [ { "name": "extracellular matrix structural constituent", "id": "GO:0005201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005201", "evidence": [ { "database": "UniProtKB", "id": "D3ZAU0", "url": "https://www.uniprot.org/uniprotkb/D3ZAU0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "D3ZAU0-1", "start_pos": "1725", "end_pos": "1725", "site_lbl": "Thr1725", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1725, "start_aa": "Thr", "end_pos": 1725, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1725", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "D3ZAU0-1", "start_pos": "3167", "end_pos": "3167", "site_lbl": "Thr3167", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 3167, "start_aa": "Thr", "end_pos": 3167, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr3167", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "D3ZAU0-1", "start_pos": "3170", "end_pos": "3170", "site_lbl": "Thr3170", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 3170, "start_aa": "Thr", "end_pos": 3170, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr3170", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "D3ZAU0-1", "start_pos": "3185", "end_pos": "3185", "site_lbl": "Thr3185", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 3185, "start_aa": "Thr", "end_pos": 3185, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr3185", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ], "snv": [ { "sequence_org": "T", "sequence_mut": "N", "comment": "Germline mutation passed 1 filters: o-glyco-site-loss (T->N).", "chr_id": "1", "chr_pos": "206370385", "evidence": [ { "id": "rs3319169019", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3319169019" } ] } ] } ], "record_id": "D3ZAU0-1" }, { "uniprot_canonical_ac": "D3ZAW9-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZAW9", "url": "https://www.uniprot.org/uniprotkb/D3ZAW9" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 310, "chemical_mass": 34913.0, "gene_names": "Or11n2;Olr1766;Or11n2;ratchrX-136465174-136464242_ORF", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "D3ZAW9", "url": "https://www.uniprot.org/uniprotkb/D3ZAW9" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "D3ZAW9", "url": "https://www.uniprot.org/uniprotkb/D3ZAW9" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "D3ZAW9", "url": "https://www.uniprot.org/uniprotkb/D3ZAW9" } ], "pmid": "" } ], "biological_process": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "D3ZAW9", "url": "https://www.uniprot.org/uniprotkb/D3ZAW9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZAW9-1" }, { "uniprot_canonical_ac": "D3ZB52-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZB52", "url": "https://www.uniprot.org/uniprotkb/D3ZB52" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 868, "chemical_mass": 94065.0, "gene_names": "Adam8;Adam8;RGD1566394", "protein_name": "", "disease": [ { "disease_id": "DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.", "url": "https://disease-ontology.org/term/DOID:2841", "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ], "weight": 0.0 }, { "disease_id": "DOID:3587", "name": "pancreatic ductal carcinoma", "description": "A pancreatic carcinoma located_in the pancreatic duct.", "url": "https://disease-ontology.org/term/DOID:3587", "evidence": [ { "id": "3587", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3587" } ], "weight": 0.0 }, { "disease_id": "DOID:9498", "name": "pulmonary eosinophilia", "description": "A hypereosinophilic syndrome characterized by the accumulation of eosinophils in the lungs.", "url": "https://disease-ontology.org/term/DOID:9498", "evidence": [ { "id": "9498", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9498" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "immunoglobulin receptor binding", "id": "GO:0034987", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034987", "evidence": [ { "database": "UniProtKB", "id": "D3ZB52", "url": "https://www.uniprot.org/uniprotkb/D3ZB52" } ], "pmid": "" }, { "name": "metalloendopeptidase activity", "id": "GO:0004222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004222", "evidence": [ { "database": "UniProtKB", "id": "D3ZB52", "url": "https://www.uniprot.org/uniprotkb/D3ZB52" } ], "pmid": "" }, { "name": "metallopeptidase activity", "id": "GO:0008237", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008237", "evidence": [ { "database": "UniProtKB", "id": "D3ZB52", "url": "https://www.uniprot.org/uniprotkb/D3ZB52" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "D3ZB52", "url": "https://www.uniprot.org/uniprotkb/D3ZB52" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "D3ZB52", "url": "https://www.uniprot.org/uniprotkb/D3ZB52" } ], "pmid": "" }, { "name": "cell adhesion molecule binding", "id": "GO:0050839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050839", "evidence": [ { "database": "UniProtKB", "id": "D3ZB52", "url": "https://www.uniprot.org/uniprotkb/D3ZB52" } ], "pmid": "" }, { "name": "tumor necrosis factor receptor superfamily binding", "id": "GO:0032813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032813", "evidence": [ { "database": "UniProtKB", "id": "D3ZB52", "url": "https://www.uniprot.org/uniprotkb/D3ZB52" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "D3ZB52", "url": "https://www.uniprot.org/uniprotkb/D3ZB52" } ], "pmid": "" } ], "biological_process": [ { "name": "angiogenesis", "id": "GO:0001525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001525", "evidence": [ { "database": "UniProtKB", "id": "D3ZB52", "url": "https://www.uniprot.org/uniprotkb/D3ZB52" } ], "pmid": "" }, { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "D3ZB52", "url": "https://www.uniprot.org/uniprotkb/D3ZB52" } ], "pmid": "" }, { "name": "inflammatory response", "id": "GO:0006954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006954", "evidence": [ { "database": "UniProtKB", "id": "D3ZB52", "url": "https://www.uniprot.org/uniprotkb/D3ZB52" } ], "pmid": "" }, { "name": "positive regulation of MAPK cascade", "id": "GO:0043410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043410", "evidence": [ { "database": "UniProtKB", "id": "D3ZB52", "url": "https://www.uniprot.org/uniprotkb/D3ZB52" } ], "pmid": "" }, { "name": "positive regulation of cell adhesion", "id": "GO:0045785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045785", "evidence": [ { "database": "UniProtKB", "id": "D3ZB52", "url": "https://www.uniprot.org/uniprotkb/D3ZB52" } ], "pmid": "" }, { "name": "positive regulation of membrane protein ectodomain proteolysis", "id": "GO:0051044", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051044", "evidence": [ { "database": "UniProtKB", "id": "D3ZB52", "url": "https://www.uniprot.org/uniprotkb/D3ZB52" } ], "pmid": "" }, { "name": "positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction", "id": "GO:0051897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051897", "evidence": [ { "database": "UniProtKB", "id": "D3ZB52", "url": "https://www.uniprot.org/uniprotkb/D3ZB52" } ], "pmid": "" }, { "name": "positive regulation of T cell migration", "id": "GO:2000406", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000406", "evidence": [ { "database": "UniProtKB", "id": "D3ZB52", "url": "https://www.uniprot.org/uniprotkb/D3ZB52" } ], "pmid": "" }, { "name": "cell morphogenesis", "id": "GO:0000902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000902", "evidence": [ { "database": "UniProtKB", "id": "D3ZB52", "url": "https://www.uniprot.org/uniprotkb/D3ZB52" } ], "pmid": "" }, { "name": "leukocyte migration involved in inflammatory response", "id": "GO:0002523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002523", "evidence": [ { "database": "UniProtKB", "id": "D3ZB52", "url": "https://www.uniprot.org/uniprotkb/D3ZB52" } ], "pmid": "" }, { "name": "positive regulation of acute inflammatory response", "id": "GO:0002675", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002675", "evidence": [ { "database": "UniProtKB", "id": "D3ZB52", "url": "https://www.uniprot.org/uniprotkb/D3ZB52" } ], "pmid": "" }, { "name": "regulation of cell-cell adhesion", "id": "GO:0022407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022407", "evidence": [ { "database": "UniProtKB", "id": "D3ZB52", "url": "https://www.uniprot.org/uniprotkb/D3ZB52" } ], "pmid": "" }, { "name": "positive regulation of T cell differentiation in thymus", "id": "GO:0033089", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033089", "evidence": [ { "database": "UniProtKB", "id": "D3ZB52", "url": "https://www.uniprot.org/uniprotkb/D3ZB52" } ], "pmid": "" }, { "name": "negative regulation of neuron apoptotic process", "id": "GO:0043524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043524", "evidence": [ { "database": "UniProtKB", "id": "D3ZB52", "url": "https://www.uniprot.org/uniprotkb/D3ZB52" } ], "pmid": "" }, { "name": "positive regulation of bone resorption", "id": "GO:0045780", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045780", "evidence": [ { "database": "UniProtKB", "id": "D3ZB52", "url": "https://www.uniprot.org/uniprotkb/D3ZB52" } ], "pmid": "" }, { "name": "lymphocyte chemotaxis", "id": "GO:0048247", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048247", "evidence": [ { "database": "UniProtKB", "id": "D3ZB52", "url": "https://www.uniprot.org/uniprotkb/D3ZB52" } ], "pmid": "" }, { "name": "positive regulation of thymocyte apoptotic process", "id": "GO:0070245", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070245", "evidence": [ { "database": "UniProtKB", "id": "D3ZB52", "url": "https://www.uniprot.org/uniprotkb/D3ZB52" } ], "pmid": "" }, { "name": "cellular response to hypoxia", "id": "GO:0071456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071456", "evidence": [ { "database": "UniProtKB", "id": "D3ZB52", "url": "https://www.uniprot.org/uniprotkb/D3ZB52" } ], "pmid": "" }, { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "D3ZB52", "url": "https://www.uniprot.org/uniprotkb/D3ZB52" } ], "pmid": "" }, { "name": "positive regulation of tumor necrosis factor (ligand) superfamily member 11 production", "id": "GO:2000309", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000309", "evidence": [ { "database": "UniProtKB", "id": "D3ZB52", "url": "https://www.uniprot.org/uniprotkb/D3ZB52" } ], "pmid": "" }, { "name": "positive regulation of neutrophil extravasation", "id": "GO:2000391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000391", "evidence": [ { "database": "UniProtKB", "id": "D3ZB52", "url": "https://www.uniprot.org/uniprotkb/D3ZB52" } ], "pmid": "" }, { "name": "positive regulation of fibronectin-dependent thymocyte migration", "id": "GO:2000415", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000415", "evidence": [ { "database": "UniProtKB", "id": "D3ZB52", "url": "https://www.uniprot.org/uniprotkb/D3ZB52" } ], "pmid": "" }, { "name": "positive regulation of eosinophil migration", "id": "GO:2000418", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000418", "evidence": [ { "database": "UniProtKB", "id": "D3ZB52", "url": "https://www.uniprot.org/uniprotkb/D3ZB52" } ], "pmid": "" }, { "name": "positive regulation of inflammatory response", "id": "GO:0050729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050729", "evidence": [ { "database": "UniProtKB", "id": "D3ZB52", "url": "https://www.uniprot.org/uniprotkb/D3ZB52" } ], "pmid": "" }, { "name": "positive regulation of epithelial to mesenchymal transition", "id": "GO:0010718", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010718", "evidence": [ { "database": "UniProtKB", "id": "D3ZB52", "url": "https://www.uniprot.org/uniprotkb/D3ZB52" } ], "pmid": "" }, { "name": "canonical NF-kappaB signal transduction", "id": "GO:0007249", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007249", "evidence": [ { "database": "UniProtKB", "id": "D3ZB52", "url": "https://www.uniprot.org/uniprotkb/D3ZB52" } ], "pmid": "" }, { "name": "positive regulation of innate immune response", "id": "GO:0045089", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045089", "evidence": [ { "database": "UniProtKB", "id": "D3ZB52", "url": "https://www.uniprot.org/uniprotkb/D3ZB52" } ], "pmid": "" }, { "name": "positive regulation of cellular extravasation", "id": "GO:0002693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002693", "evidence": [ { "database": "UniProtKB", "id": "D3ZB52", "url": "https://www.uniprot.org/uniprotkb/D3ZB52" } ], "pmid": "" }, { "name": "signal release", "id": "GO:0023061", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0023061", "evidence": [ { "database": "UniProtKB", "id": "D3ZB52", "url": "https://www.uniprot.org/uniprotkb/D3ZB52" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "D3ZB52", "url": "https://www.uniprot.org/uniprotkb/D3ZB52" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "D3ZB52", "url": "https://www.uniprot.org/uniprotkb/D3ZB52" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "D3ZB52", "url": "https://www.uniprot.org/uniprotkb/D3ZB52" } ], "pmid": "" }, { "name": "podosome", "id": "GO:0002102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002102", "evidence": [ { "database": "UniProtKB", "id": "D3ZB52", "url": "https://www.uniprot.org/uniprotkb/D3ZB52" } ], "pmid": "" }, { "name": "phagolysosome", "id": "GO:0032010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032010", "evidence": [ { "database": "UniProtKB", "id": "D3ZB52", "url": "https://www.uniprot.org/uniprotkb/D3ZB52" } ], "pmid": "" }, { "name": "dense core granule membrane", "id": "GO:0032127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032127", "evidence": [ { "database": "UniProtKB", "id": "D3ZB52", "url": "https://www.uniprot.org/uniprotkb/D3ZB52" } ], "pmid": "" }, { "name": "specific granule", "id": "GO:0042581", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042581", "evidence": [ { "database": "UniProtKB", "id": "D3ZB52", "url": "https://www.uniprot.org/uniprotkb/D3ZB52" } ], "pmid": "" }, { "name": "tertiary granule", "id": "GO:0070820", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070820", "evidence": [ { "database": "UniProtKB", "id": "D3ZB52", "url": "https://www.uniprot.org/uniprotkb/D3ZB52" } ], "pmid": "" }, { "name": "alpha9-beta1 integrin-ADAM8 complex", "id": "GO:0071133", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071133", "evidence": [ { "database": "UniProtKB", "id": "D3ZB52", "url": "https://www.uniprot.org/uniprotkb/D3ZB52" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "D3ZB52", "url": "https://www.uniprot.org/uniprotkb/D3ZB52" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "D3ZB52-1", "start_pos": "741", "end_pos": "741", "site_lbl": "Thr741", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 741, "start_aa": "Thr", "end_pos": 741, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr741", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "D3ZB52-1" }, { "uniprot_canonical_ac": "D3ZB65-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZB65", "url": "https://www.uniprot.org/uniprotkb/D3ZB65" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 370, "chemical_mass": 41718.0, "gene_names": "Bccip", "protein_name": "", "disease": [], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "D3ZB65", "url": "https://www.uniprot.org/uniprotkb/D3ZB65" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "D3ZB65", "url": "https://www.uniprot.org/uniprotkb/D3ZB65" } ], "pmid": "" }, { "name": "tubulin binding", "id": "GO:0015631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015631", "evidence": [ { "database": "UniProtKB", "id": "D3ZB65", "url": "https://www.uniprot.org/uniprotkb/D3ZB65" } ], "pmid": "" }, { "name": "kinase regulator activity", "id": "GO:0019207", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019207", "evidence": [ { "database": "UniProtKB", "id": "D3ZB65", "url": "https://www.uniprot.org/uniprotkb/D3ZB65" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D3ZB65", "url": "https://www.uniprot.org/uniprotkb/D3ZB65" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "D3ZB65", "url": "https://www.uniprot.org/uniprotkb/D3ZB65" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "D3ZB65", "url": "https://www.uniprot.org/uniprotkb/D3ZB65" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "D3ZB65", "url": "https://www.uniprot.org/uniprotkb/D3ZB65" } ], "pmid": "" }, { "name": "mitotic spindle pole", "id": "GO:0097431", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097431", "evidence": [ { "database": "UniProtKB", "id": "D3ZB65", "url": "https://www.uniprot.org/uniprotkb/D3ZB65" } ], "pmid": "" }, { "name": "nuclear cyclin-dependent protein kinase holoenzyme complex", "id": "GO:0019908", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019908", "evidence": [ { "database": "UniProtKB", "id": "D3ZB65", "url": "https://www.uniprot.org/uniprotkb/D3ZB65" } ], "pmid": "" }, { "name": "spindle pole", "id": "GO:0000922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000922", "evidence": [ { "database": "UniProtKB", "id": "D3ZB65", "url": "https://www.uniprot.org/uniprotkb/D3ZB65" } ], "pmid": "" } ], "biological_process": [ { "name": "mitotic spindle assembly", "id": "GO:0090307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090307", "evidence": [ { "database": "UniProtKB", "id": "D3ZB65", "url": "https://www.uniprot.org/uniprotkb/D3ZB65" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "D3ZB65", "url": "https://www.uniprot.org/uniprotkb/D3ZB65" } ], "pmid": "" }, { "name": "regulation of cyclin-dependent protein serine/threonine kinase activity", "id": "GO:0000079", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000079", "evidence": [ { "database": "UniProtKB", "id": "D3ZB65", "url": "https://www.uniprot.org/uniprotkb/D3ZB65" } ], "pmid": "" }, { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "D3ZB65", "url": "https://www.uniprot.org/uniprotkb/D3ZB65" } ], "pmid": "" }, { "name": "establishment of mitotic spindle orientation", "id": "GO:0000132", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000132", "evidence": [ { "database": "UniProtKB", "id": "D3ZB65", "url": "https://www.uniprot.org/uniprotkb/D3ZB65" } ], "pmid": "" }, { "name": "mitotic spindle organization", "id": "GO:0007052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007052", "evidence": [ { "database": "UniProtKB", "id": "D3ZB65", "url": "https://www.uniprot.org/uniprotkb/D3ZB65" } ], "pmid": "" }, { "name": "microtubule anchoring", "id": "GO:0034453", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034453", "evidence": [ { "database": "UniProtKB", "id": "D3ZB65", "url": "https://www.uniprot.org/uniprotkb/D3ZB65" } ], "pmid": "" }, { "name": "neuroendocrine cell differentiation", "id": "GO:0061101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061101", "evidence": [ { "database": "UniProtKB", "id": "D3ZB65", "url": "https://www.uniprot.org/uniprotkb/D3ZB65" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZB65-1" }, { "uniprot_canonical_ac": "D3ZBF6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZBF6", "url": "https://www.uniprot.org/uniprotkb/D3ZBF6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 586, "chemical_mass": 65300.0, "gene_names": "Tchhl1;RGD1308305;Tchhl1", "protein_name": "", "disease": [], "molecular_function": [ { "name": "transition metal ion binding", "id": "GO:0046914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046914", "evidence": [ { "database": "UniProtKB", "id": "D3ZBF6", "url": "https://www.uniprot.org/uniprotkb/D3ZBF6" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "D3ZBF6", "url": "https://www.uniprot.org/uniprotkb/D3ZBF6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "D3ZBF6-1", "start_pos": "126", "end_pos": "126", "site_lbl": "Thr126", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 126, "start_aa": "Thr", "end_pos": 126, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr126", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "D3ZBF6-1", "start_pos": "294", "end_pos": "294", "site_lbl": "Asp294", "weight": 0.0, "snv": [ { "sequence_org": "D", "sequence_mut": "N", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (DDT->NDT).", "chr_id": "2", "chr_pos": "181820600", "evidence": [ { "id": "rs3319643099", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3319643099" } ] } ] } ], "record_id": "D3ZBF6-1" }, { "uniprot_canonical_ac": "D3ZBL0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZBL0", "url": "https://www.uniprot.org/uniprotkb/D3ZBL0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 152, "chemical_mass": 17580.0, "gene_names": "Arl14epl;Arl14epl", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZBL0-1" }, { "uniprot_canonical_ac": "D3ZBL7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZBL7", "url": "https://www.uniprot.org/uniprotkb/D3ZBL7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 314, "chemical_mass": 35458.0, "gene_names": "Or4k50;Olr771;Or4k50", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "D3ZBL7", "url": "https://www.uniprot.org/uniprotkb/D3ZBL7" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "D3ZBL7", "url": "https://www.uniprot.org/uniprotkb/D3ZBL7" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "D3ZBL7", "url": "https://www.uniprot.org/uniprotkb/D3ZBL7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZBL7-1" }, { "uniprot_canonical_ac": "D3ZBS8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZBS8", "url": "https://www.uniprot.org/uniprotkb/D3ZBS8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 531, "chemical_mass": 59672.0, "gene_names": "Smokl5;LOC100365174;LOC690235", "protein_name": "non-specific serine/threonine protein kinase", "disease": [], "molecular_function": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "D3ZBS8", "url": "https://www.uniprot.org/uniprotkb/D3ZBS8" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "D3ZBS8", "url": "https://www.uniprot.org/uniprotkb/D3ZBS8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZBS8-1" }, { "uniprot_canonical_ac": "D3ZBT2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZBT2", "url": "https://www.uniprot.org/uniprotkb/D3ZBT2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 97, "chemical_mass": 11087.0, "gene_names": "Bbln;RGD1561113", "protein_name": "", "disease": [], "cellular_component": [ { "name": "kinetochore microtubule", "id": "GO:0005828", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005828", "evidence": [ { "database": "UniProtKB", "id": "D3ZBT2", "url": "https://www.uniprot.org/uniprotkb/D3ZBT2" } ], "pmid": "" }, { "name": "cell junction", "id": "GO:0030054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030054", "evidence": [ { "database": "UniProtKB", "id": "D3ZBT2", "url": "https://www.uniprot.org/uniprotkb/D3ZBT2" } ], "pmid": "" }, { "name": "intermediate filament", "id": "GO:0005882", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005882", "evidence": [ { "database": "UniProtKB", "id": "D3ZBT2", "url": "https://www.uniprot.org/uniprotkb/D3ZBT2" } ], "pmid": "" }, { "name": "subapical part of cell", "id": "GO:0120219", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120219", "evidence": [ { "database": "UniProtKB", "id": "D3ZBT2", "url": "https://www.uniprot.org/uniprotkb/D3ZBT2" } ], "pmid": "" } ], "biological_process": [ { "name": "osteoclast differentiation", "id": "GO:0030316", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030316", "evidence": [ { "database": "UniProtKB", "id": "D3ZBT2", "url": "https://www.uniprot.org/uniprotkb/D3ZBT2" } ], "pmid": "" }, { "name": "intermediate filament bundle assembly", "id": "GO:0045110", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045110", "evidence": [ { "database": "UniProtKB", "id": "D3ZBT2", "url": "https://www.uniprot.org/uniprotkb/D3ZBT2" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "D3ZBT2", "url": "https://www.uniprot.org/uniprotkb/D3ZBT2" } ], "pmid": "" }, { "name": "apoptotic signaling pathway", "id": "GO:0097190", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097190", "evidence": [ { "database": "UniProtKB", "id": "D3ZBT2", "url": "https://www.uniprot.org/uniprotkb/D3ZBT2" } ], "pmid": "" }, { "name": "regulation of catalytic activity", "id": "GO:0050790", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050790", "evidence": [ { "database": "UniProtKB", "id": "D3ZBT2", "url": "https://www.uniprot.org/uniprotkb/D3ZBT2" } ], "pmid": "" }, { "name": "bone resorption", "id": "GO:0045453", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045453", "evidence": [ { "database": "UniProtKB", "id": "D3ZBT2", "url": "https://www.uniprot.org/uniprotkb/D3ZBT2" } ], "pmid": "" }, { "name": "bone development", "id": "GO:0060348", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060348", "evidence": [ { "database": "UniProtKB", "id": "D3ZBT2", "url": "https://www.uniprot.org/uniprotkb/D3ZBT2" } ], "pmid": "" }, { "name": "gene expression", "id": "GO:0010467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010467", "evidence": [ { "database": "UniProtKB", "id": "D3ZBT2", "url": "https://www.uniprot.org/uniprotkb/D3ZBT2" } ], "pmid": "" }, { "name": "multinuclear osteoclast differentiation", "id": "GO:0072674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072674", "evidence": [ { "database": "UniProtKB", "id": "D3ZBT2", "url": "https://www.uniprot.org/uniprotkb/D3ZBT2" } ], "pmid": "" } ], "molecular_function": [ { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "D3ZBT2", "url": "https://www.uniprot.org/uniprotkb/D3ZBT2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZBT2-1" }, { "uniprot_canonical_ac": "D3ZBT8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZBT8", "url": "https://www.uniprot.org/uniprotkb/D3ZBT8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 312, "chemical_mass": 34958.0, "gene_names": "Or5w1;Olr577;Or5w1", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "D3ZBT8", "url": "https://www.uniprot.org/uniprotkb/D3ZBT8" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "D3ZBT8", "url": "https://www.uniprot.org/uniprotkb/D3ZBT8" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "D3ZBT8", "url": "https://www.uniprot.org/uniprotkb/D3ZBT8" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "D3ZBT8", "url": "https://www.uniprot.org/uniprotkb/D3ZBT8" } ], "pmid": "" } ], "biological_process": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "D3ZBT8", "url": "https://www.uniprot.org/uniprotkb/D3ZBT8" } ], "pmid": "" }, { "name": "sensory perception of smell", "id": "GO:0007608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007608", "evidence": [ { "database": "UniProtKB", "id": "D3ZBT8", "url": "https://www.uniprot.org/uniprotkb/D3ZBT8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZBT8-1" }, { "uniprot_canonical_ac": "D3ZC15-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZC15", "url": "https://www.uniprot.org/uniprotkb/D3ZC15" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1368, "chemical_mass": 148360.0, "gene_names": "Carmil2;Carmil2;RGD1562390;Rltpr", "protein_name": "", "disease": [ { "disease_id": "DOID:0111984", "name": "immunodeficiency 58", "description": "A combined T cell and B cell immunodeficiency characterized by defective T-cell function with decreased Treg cells and deficient CD3/CD28 costimulation responses in both CD4+ and CD8+ T cells, variable impairment in B-cell function, early-onset skin lesions, recurrent respiratory infections or allergies, and chronic persistent infections that has_material_basis_in homozygous or compound heterozygous mutation in the CARMIL2 gene on chromosome 16q22.1.", "url": "https://disease-ontology.org/term/DOID:0111984", "evidence": [ { "id": "0111984", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111984" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "phospholipid binding", "id": "GO:0005543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005543", "evidence": [ { "database": "UniProtKB", "id": "D3ZC15", "url": "https://www.uniprot.org/uniprotkb/D3ZC15" } ], "pmid": "" }, { "name": "protein-containing complex binding", "id": "GO:0044877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044877", "evidence": [ { "database": "UniProtKB", "id": "D3ZC15", "url": "https://www.uniprot.org/uniprotkb/D3ZC15" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "D3ZC15", "url": "https://www.uniprot.org/uniprotkb/D3ZC15" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "D3ZC15", "url": "https://www.uniprot.org/uniprotkb/D3ZC15" } ], "pmid": "" }, { "name": "cell-cell junction", "id": "GO:0005911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005911", "evidence": [ { "database": "UniProtKB", "id": "D3ZC15", "url": "https://www.uniprot.org/uniprotkb/D3ZC15" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "D3ZC15", "url": "https://www.uniprot.org/uniprotkb/D3ZC15" } ], "pmid": "" }, { "name": "lamellipodium", "id": "GO:0030027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030027", "evidence": [ { "database": "UniProtKB", "id": "D3ZC15", "url": "https://www.uniprot.org/uniprotkb/D3ZC15" } ], "pmid": "" }, { "name": "cell leading edge", "id": "GO:0031252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031252", "evidence": [ { "database": "UniProtKB", "id": "D3ZC15", "url": "https://www.uniprot.org/uniprotkb/D3ZC15" } ], "pmid": "" }, { "name": "F-actin capping protein complex", "id": "GO:0008290", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008290", "evidence": [ { "database": "UniProtKB", "id": "D3ZC15", "url": "https://www.uniprot.org/uniprotkb/D3ZC15" } ], "pmid": "" }, { "name": "ruffle", "id": "GO:0001726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001726", "evidence": [ { "database": "UniProtKB", "id": "D3ZC15", "url": "https://www.uniprot.org/uniprotkb/D3ZC15" } ], "pmid": "" }, { "name": "macropinosome", "id": "GO:0044354", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044354", "evidence": [ { "database": "UniProtKB", "id": "D3ZC15", "url": "https://www.uniprot.org/uniprotkb/D3ZC15" } ], "pmid": "" }, { "name": "intermediate filament cytoskeleton", "id": "GO:0045111", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045111", "evidence": [ { "database": "UniProtKB", "id": "D3ZC15", "url": "https://www.uniprot.org/uniprotkb/D3ZC15" } ], "pmid": "" }, { "name": "immunological synapse", "id": "GO:0001772", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001772", "evidence": [ { "database": "UniProtKB", "id": "D3ZC15", "url": "https://www.uniprot.org/uniprotkb/D3ZC15" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of cell migration", "id": "GO:0030335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030335", "evidence": [ { "database": "UniProtKB", "id": "D3ZC15", "url": "https://www.uniprot.org/uniprotkb/D3ZC15" } ], "pmid": "" }, { "name": "T cell receptor signaling pathway", "id": "GO:0050852", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050852", "evidence": [ { "database": "UniProtKB", "id": "D3ZC15", "url": "https://www.uniprot.org/uniprotkb/D3ZC15" } ], "pmid": "" }, { "name": "establishment of protein localization", "id": "GO:0045184", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045184", "evidence": [ { "database": "UniProtKB", "id": "D3ZC15", "url": "https://www.uniprot.org/uniprotkb/D3ZC15" } ], "pmid": "" }, { "name": "thymus development", "id": "GO:0048538", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048538", "evidence": [ { "database": "UniProtKB", "id": "D3ZC15", "url": "https://www.uniprot.org/uniprotkb/D3ZC15" } ], "pmid": "" }, { "name": "positive regulation of type II interferon production", "id": "GO:0032729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032729", "evidence": [ { "database": "UniProtKB", "id": "D3ZC15", "url": "https://www.uniprot.org/uniprotkb/D3ZC15" } ], "pmid": "" }, { "name": "actin filament network formation", "id": "GO:0051639", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051639", "evidence": [ { "database": "UniProtKB", "id": "D3ZC15", "url": "https://www.uniprot.org/uniprotkb/D3ZC15" } ], "pmid": "" }, { "name": "positive regulation of T cell proliferation", "id": "GO:0042102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042102", "evidence": [ { "database": "UniProtKB", "id": "D3ZC15", "url": "https://www.uniprot.org/uniprotkb/D3ZC15" } ], "pmid": "" }, { "name": "positive regulation of interleukin-2 production", "id": "GO:0032743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032743", "evidence": [ { "database": "UniProtKB", "id": "D3ZC15", "url": "https://www.uniprot.org/uniprotkb/D3ZC15" } ], "pmid": "" }, { "name": "positive regulation of lamellipodium assembly", "id": "GO:0010592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010592", "evidence": [ { "database": "UniProtKB", "id": "D3ZC15", "url": "https://www.uniprot.org/uniprotkb/D3ZC15" } ], "pmid": "" }, { "name": "establishment or maintenance of cell polarity", "id": "GO:0007163", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007163", "evidence": [ { "database": "UniProtKB", "id": "D3ZC15", "url": "https://www.uniprot.org/uniprotkb/D3ZC15" } ], "pmid": "" }, { "name": "homeostasis of number of cells", "id": "GO:0048872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048872", "evidence": [ { "database": "UniProtKB", "id": "D3ZC15", "url": "https://www.uniprot.org/uniprotkb/D3ZC15" } ], "pmid": "" }, { "name": "positive regulation of regulatory T cell differentiation", "id": "GO:0045591", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045591", "evidence": [ { "database": "UniProtKB", "id": "D3ZC15", "url": "https://www.uniprot.org/uniprotkb/D3ZC15" } ], "pmid": "" }, { "name": "wound healing, spreading of cells", "id": "GO:0044319", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044319", "evidence": [ { "database": "UniProtKB", "id": "D3ZC15", "url": "https://www.uniprot.org/uniprotkb/D3ZC15" } ], "pmid": "" }, { "name": "establishment or maintenance of monopolar cell polarity", "id": "GO:0061339", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061339", "evidence": [ { "database": "UniProtKB", "id": "D3ZC15", "url": "https://www.uniprot.org/uniprotkb/D3ZC15" } ], "pmid": "" }, { "name": "positive regulation of extracellular matrix disassembly", "id": "GO:0090091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090091", "evidence": [ { "database": "UniProtKB", "id": "D3ZC15", "url": "https://www.uniprot.org/uniprotkb/D3ZC15" } ], "pmid": "" }, { "name": "positive regulation of ruffle assembly", "id": "GO:1900029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900029", "evidence": [ { "database": "UniProtKB", "id": "D3ZC15", "url": "https://www.uniprot.org/uniprotkb/D3ZC15" } ], "pmid": "" }, { "name": "positive regulation of lamellipodium organization", "id": "GO:1902745", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902745", "evidence": [ { "database": "UniProtKB", "id": "D3ZC15", "url": "https://www.uniprot.org/uniprotkb/D3ZC15" } ], "pmid": "" }, { "name": "negative regulation of barbed-end actin filament capping", "id": "GO:2000813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000813", "evidence": [ { "database": "UniProtKB", "id": "D3ZC15", "url": "https://www.uniprot.org/uniprotkb/D3ZC15" } ], "pmid": "" }, { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "D3ZC15", "url": "https://www.uniprot.org/uniprotkb/D3ZC15" } ], "pmid": "" }, { "name": "regulation of Arp2/3 complex-mediated actin nucleation", "id": "GO:0034315", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034315", "evidence": [ { "database": "UniProtKB", "id": "D3ZC15", "url": "https://www.uniprot.org/uniprotkb/D3ZC15" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "D3ZC15-1", "start_pos": "1345", "end_pos": "1345", "site_lbl": "Thr1345", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1345, "start_aa": "Thr", "end_pos": 1345, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1345", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "D3ZC15-1" }, { "uniprot_canonical_ac": "D3ZCP9-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZCP9", "url": "https://www.uniprot.org/uniprotkb/D3ZCP9" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 300, "chemical_mass": 33978.0, "gene_names": "Gtf2e2", "protein_name": "Transcription initiation factor IIE subunit beta", "disease": [ { "disease_id": "DOID:0111872", "name": "nonphotosensitive trichothiodystrophy 6", "description": "A nonphotosensitive trichothiodystrophy that has_material_basis_in homozygous or compound heterozygous mutation in the GTF2E2 gene on chromosome 8p12.", "url": "https://disease-ontology.org/term/DOID:0111872", "evidence": [ { "id": "0111872", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111872" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "transcription factor TFIIE complex", "id": "GO:0005673", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005673", "evidence": [ { "database": "UniProtKB", "id": "D3ZCP9", "url": "https://www.uniprot.org/uniprotkb/D3ZCP9" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D3ZCP9", "url": "https://www.uniprot.org/uniprotkb/D3ZCP9" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "D3ZCP9", "url": "https://www.uniprot.org/uniprotkb/D3ZCP9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "D3ZCP9", "url": "https://www.uniprot.org/uniprotkb/D3ZCP9" } ], "pmid": "" }, { "name": "transcription factor TFIID complex", "id": "GO:0005669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005669", "evidence": [ { "database": "UniProtKB", "id": "D3ZCP9", "url": "https://www.uniprot.org/uniprotkb/D3ZCP9" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "D3ZCP9", "url": "https://www.uniprot.org/uniprotkb/D3ZCP9" } ], "pmid": "" }, { "name": "RNA polymerase II general transcription initiation factor activity", "id": "GO:0016251", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016251", "evidence": [ { "database": "UniProtKB", "id": "D3ZCP9", "url": "https://www.uniprot.org/uniprotkb/D3ZCP9" } ], "pmid": "" } ], "biological_process": [ { "name": "transcription by RNA polymerase II", "id": "GO:0006366", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006366", "evidence": [ { "database": "UniProtKB", "id": "D3ZCP9", "url": "https://www.uniprot.org/uniprotkb/D3ZCP9" } ], "pmid": "" }, { "name": "transcription initiation at RNA polymerase II promoter", "id": "GO:0006367", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006367", "evidence": [ { "database": "UniProtKB", "id": "D3ZCP9", "url": "https://www.uniprot.org/uniprotkb/D3ZCP9" } ], "pmid": "" }, { "name": "RNA polymerase II preinitiation complex assembly", "id": "GO:0051123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051123", "evidence": [ { "database": "UniProtKB", "id": "D3ZCP9", "url": "https://www.uniprot.org/uniprotkb/D3ZCP9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZCP9-1" }, { "uniprot_canonical_ac": "D3ZCW6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZCW6", "url": "https://www.uniprot.org/uniprotkb/D3ZCW6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 2121, "chemical_mass": 240518.0, "gene_names": "Pkdrej;Pkdrej", "protein_name": "Polycystin family receptor for egg jelly", "disease": [], "molecular_function": [ { "name": "calcium channel activity", "id": "GO:0005262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005262", "evidence": [ { "database": "UniProtKB", "id": "D3ZCW6", "url": "https://www.uniprot.org/uniprotkb/D3ZCW6" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "D3ZCW6", "url": "https://www.uniprot.org/uniprotkb/D3ZCW6" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D3ZCW6", "url": "https://www.uniprot.org/uniprotkb/D3ZCW6" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "D3ZCW6", "url": "https://www.uniprot.org/uniprotkb/D3ZCW6" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "D3ZCW6", "url": "https://www.uniprot.org/uniprotkb/D3ZCW6" } ], "pmid": "" }, { "name": "acrosomal membrane", "id": "GO:0002080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002080", "evidence": [ { "database": "UniProtKB", "id": "D3ZCW6", "url": "https://www.uniprot.org/uniprotkb/D3ZCW6" } ], "pmid": "" } ], "biological_process": [ { "name": "detection of mechanical stimulus", "id": "GO:0050982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050982", "evidence": [ { "database": "UniProtKB", "id": "D3ZCW6", "url": "https://www.uniprot.org/uniprotkb/D3ZCW6" } ], "pmid": "" }, { "name": "regulation of acrosome reaction", "id": "GO:0060046", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060046", "evidence": [ { "database": "UniProtKB", "id": "D3ZCW6", "url": "https://www.uniprot.org/uniprotkb/D3ZCW6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "D3ZCW6-1", "start_pos": "400", "end_pos": "400", "site_lbl": "Thr400", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 400, "start_aa": "Thr", "end_pos": 400, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr400", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "D3ZCW6-1" }, { "uniprot_canonical_ac": "D3ZD18-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZD18", "url": "https://www.uniprot.org/uniprotkb/D3ZD18" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 397, "chemical_mass": 46316.0, "gene_names": "Stk32a;Stk32a", "protein_name": "Serine/threonine-protein kinase 32A", "disease": [], "molecular_function": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "D3ZD18", "url": "https://www.uniprot.org/uniprotkb/D3ZD18" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "D3ZD18", "url": "https://www.uniprot.org/uniprotkb/D3ZD18" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "D3ZD18", "url": "https://www.uniprot.org/uniprotkb/D3ZD18" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "D3ZD18", "url": "https://www.uniprot.org/uniprotkb/D3ZD18" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "D3ZD18", "url": "https://www.uniprot.org/uniprotkb/D3ZD18" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZD18-1" }, { "uniprot_canonical_ac": "D3ZDM8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZDM8", "url": "https://www.uniprot.org/uniprotkb/D3ZDM8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 678, "chemical_mass": 78048.0, "gene_names": "Zfp334;AABR07054578.1;Zfp334", "protein_name": "Zinc finger protein 334", "disease": [], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "D3ZDM8", "url": "https://www.uniprot.org/uniprotkb/D3ZDM8" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "D3ZDM8", "url": "https://www.uniprot.org/uniprotkb/D3ZDM8" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D3ZDM8", "url": "https://www.uniprot.org/uniprotkb/D3ZDM8" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "D3ZDM8", "url": "https://www.uniprot.org/uniprotkb/D3ZDM8" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "D3ZDM8", "url": "https://www.uniprot.org/uniprotkb/D3ZDM8" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "D3ZDM8", "url": "https://www.uniprot.org/uniprotkb/D3ZDM8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZDM8-1" }, { "uniprot_canonical_ac": "D3ZDQ2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZDQ2", "url": "https://www.uniprot.org/uniprotkb/D3ZDQ2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 330, "chemical_mass": 36279.0, "gene_names": "Nkx2-2", "protein_name": "", "disease": [ { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 }, { "disease_id": "DOID:3213", "name": "demyelinating disease", "description": "A central nervous system disease that is characterized by damage to the myelin sheath present around nerve axons.", "url": "https://disease-ontology.org/term/DOID:3213", "evidence": [ { "id": "3213", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3213" } ], "weight": 0.0 } ], "biological_process": [ { "name": "astrocyte differentiation", "id": "GO:0048708", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048708", "evidence": [ { "database": "UniProtKB", "id": "D3ZDQ2", "url": "https://www.uniprot.org/uniprotkb/D3ZDQ2" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "D3ZDQ2", "url": "https://www.uniprot.org/uniprotkb/D3ZDQ2" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "D3ZDQ2", "url": "https://www.uniprot.org/uniprotkb/D3ZDQ2" } ], "pmid": "" }, { "name": "positive regulation of gene expression", "id": "GO:0010628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010628", "evidence": [ { "database": "UniProtKB", "id": "D3ZDQ2", "url": "https://www.uniprot.org/uniprotkb/D3ZDQ2" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "D3ZDQ2", "url": "https://www.uniprot.org/uniprotkb/D3ZDQ2" } ], "pmid": "" }, { "name": "negative regulation of neuron differentiation", "id": "GO:0045665", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045665", "evidence": [ { "database": "UniProtKB", "id": "D3ZDQ2", "url": "https://www.uniprot.org/uniprotkb/D3ZDQ2" } ], "pmid": "" }, { "name": "positive regulation of neuron differentiation", "id": "GO:0045666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045666", "evidence": [ { "database": "UniProtKB", "id": "D3ZDQ2", "url": "https://www.uniprot.org/uniprotkb/D3ZDQ2" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "D3ZDQ2", "url": "https://www.uniprot.org/uniprotkb/D3ZDQ2" } ], "pmid": "" }, { "name": "positive regulation of oligodendrocyte differentiation", "id": "GO:0048714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048714", "evidence": [ { "database": "UniProtKB", "id": "D3ZDQ2", "url": "https://www.uniprot.org/uniprotkb/D3ZDQ2" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "D3ZDQ2", "url": "https://www.uniprot.org/uniprotkb/D3ZDQ2" } ], "pmid": "" }, { "name": "response to progesterone", "id": "GO:0032570", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032570", "evidence": [ { "database": "UniProtKB", "id": "D3ZDQ2", "url": "https://www.uniprot.org/uniprotkb/D3ZDQ2" } ], "pmid": "" }, { "name": "positive regulation of cell differentiation", "id": "GO:0045597", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045597", "evidence": [ { "database": "UniProtKB", "id": "D3ZDQ2", "url": "https://www.uniprot.org/uniprotkb/D3ZDQ2" } ], "pmid": "" }, { "name": "spinal cord motor neuron differentiation", "id": "GO:0021522", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021522", "evidence": [ { "database": "UniProtKB", "id": "D3ZDQ2", "url": "https://www.uniprot.org/uniprotkb/D3ZDQ2" } ], "pmid": "" }, { "name": "response to glucose", "id": "GO:0009749", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009749", "evidence": [ { "database": "UniProtKB", "id": "D3ZDQ2", "url": "https://www.uniprot.org/uniprotkb/D3ZDQ2" } ], "pmid": "" }, { "name": "digestive tract development", "id": "GO:0048565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048565", "evidence": [ { "database": "UniProtKB", "id": "D3ZDQ2", "url": "https://www.uniprot.org/uniprotkb/D3ZDQ2" } ], "pmid": "" }, { "name": "endocrine pancreas development", "id": "GO:0031018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031018", "evidence": [ { "database": "UniProtKB", "id": "D3ZDQ2", "url": "https://www.uniprot.org/uniprotkb/D3ZDQ2" } ], "pmid": "" }, { "name": "smoothened signaling pathway", "id": "GO:0007224", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007224", "evidence": [ { "database": "UniProtKB", "id": "D3ZDQ2", "url": "https://www.uniprot.org/uniprotkb/D3ZDQ2" } ], "pmid": "" }, { "name": "optic nerve development", "id": "GO:0021554", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021554", "evidence": [ { "database": "UniProtKB", "id": "D3ZDQ2", "url": "https://www.uniprot.org/uniprotkb/D3ZDQ2" } ], "pmid": "" }, { "name": "oligodendrocyte development", "id": "GO:0014003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014003", "evidence": [ { "database": "UniProtKB", "id": "D3ZDQ2", "url": "https://www.uniprot.org/uniprotkb/D3ZDQ2" } ], "pmid": "" }, { "name": "spinal cord oligodendrocyte cell fate specification", "id": "GO:0021530", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021530", "evidence": [ { "database": "UniProtKB", "id": "D3ZDQ2", "url": "https://www.uniprot.org/uniprotkb/D3ZDQ2" } ], "pmid": "" }, { "name": "cell development", "id": "GO:0048468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048468", "evidence": [ { "database": "UniProtKB", "id": "D3ZDQ2", "url": "https://www.uniprot.org/uniprotkb/D3ZDQ2" } ], "pmid": "" }, { "name": "neuron fate specification", "id": "GO:0048665", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048665", "evidence": [ { "database": "UniProtKB", "id": "D3ZDQ2", "url": "https://www.uniprot.org/uniprotkb/D3ZDQ2" } ], "pmid": "" }, { "name": "type B pancreatic cell development", "id": "GO:0003323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003323", "evidence": [ { "database": "UniProtKB", "id": "D3ZDQ2", "url": "https://www.uniprot.org/uniprotkb/D3ZDQ2" } ], "pmid": "" }, { "name": "pancreatic A cell fate commitment", "id": "GO:0003326", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003326", "evidence": [ { "database": "UniProtKB", "id": "D3ZDQ2", "url": "https://www.uniprot.org/uniprotkb/D3ZDQ2" } ], "pmid": "" }, { "name": "pancreatic PP cell fate commitment", "id": "GO:0003329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003329", "evidence": [ { "database": "UniProtKB", "id": "D3ZDQ2", "url": "https://www.uniprot.org/uniprotkb/D3ZDQ2" } ], "pmid": "" }, { "name": "type B pancreatic cell fate commitment", "id": "GO:0003327", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003327", "evidence": [ { "database": "UniProtKB", "id": "D3ZDQ2", "url": "https://www.uniprot.org/uniprotkb/D3ZDQ2" } ], "pmid": "" }, { "name": "ventral spinal cord interneuron fate determination", "id": "GO:0060580", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060580", "evidence": [ { "database": "UniProtKB", "id": "D3ZDQ2", "url": "https://www.uniprot.org/uniprotkb/D3ZDQ2" } ], "pmid": "" }, { "name": "spinal cord oligodendrocyte cell differentiation", "id": "GO:0021529", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021529", "evidence": [ { "database": "UniProtKB", "id": "D3ZDQ2", "url": "https://www.uniprot.org/uniprotkb/D3ZDQ2" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "D3ZDQ2", "url": "https://www.uniprot.org/uniprotkb/D3ZDQ2" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "D3ZDQ2", "url": "https://www.uniprot.org/uniprotkb/D3ZDQ2" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "D3ZDQ2", "url": "https://www.uniprot.org/uniprotkb/D3ZDQ2" } ], "pmid": "" }, { "name": "cis-regulatory region sequence-specific DNA binding", "id": "GO:0000987", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000987", "evidence": [ { "database": "UniProtKB", "id": "D3ZDQ2", "url": "https://www.uniprot.org/uniprotkb/D3ZDQ2" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "D3ZDQ2", "url": "https://www.uniprot.org/uniprotkb/D3ZDQ2" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "D3ZDQ2", "url": "https://www.uniprot.org/uniprotkb/D3ZDQ2" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D3ZDQ2", "url": "https://www.uniprot.org/uniprotkb/D3ZDQ2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZDQ2-1" }, { "uniprot_canonical_ac": "D3ZEB4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZEB4", "url": "https://www.uniprot.org/uniprotkb/D3ZEB4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 326, "chemical_mass": 35234.0, "gene_names": "Zglp1", "protein_name": "GATA-type zinc finger protein 1", "disease": [], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "D3ZEB4", "url": "https://www.uniprot.org/uniprotkb/D3ZEB4" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "D3ZEB4", "url": "https://www.uniprot.org/uniprotkb/D3ZEB4" } ], "pmid": "" }, { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "D3ZEB4", "url": "https://www.uniprot.org/uniprotkb/D3ZEB4" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "D3ZEB4", "url": "https://www.uniprot.org/uniprotkb/D3ZEB4" } ], "pmid": "" }, { "name": "oocyte development", "id": "GO:0048599", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048599", "evidence": [ { "database": "UniProtKB", "id": "D3ZEB4", "url": "https://www.uniprot.org/uniprotkb/D3ZEB4" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D3ZEB4", "url": "https://www.uniprot.org/uniprotkb/D3ZEB4" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "D3ZEB4", "url": "https://www.uniprot.org/uniprotkb/D3ZEB4" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "D3ZEB4", "url": "https://www.uniprot.org/uniprotkb/D3ZEB4" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "D3ZEB4", "url": "https://www.uniprot.org/uniprotkb/D3ZEB4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "D3ZEB4-1", "start_pos": "58", "end_pos": "58", "site_lbl": "Thr58", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 58, "start_aa": "Thr", "end_pos": 58, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr58", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "D3ZEB4-1" }, { "uniprot_canonical_ac": "D3ZEH1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZEH1", "url": "https://www.uniprot.org/uniprotkb/D3ZEH1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 4982, "chemical_mass": 540457.0, "gene_names": "Fat4", "protein_name": "Protocadherin Fat 4", "disease": [ { "disease_id": "DOID:0060366", "name": "Hennekam syndrome", "description": "A lymphatic system disease characterized by he presence of intestinal lymphangiectasia, mental retardation, and characteristic facial anomalies. It is inherited in an autosomal recessive pattern. Most individuals with Hennekam syndrome have characteristic facial abnormalities, such as a flat face with accompanying puffy eyelids and hypertelorism; the nasal bridge is typically flat and the ears are typically small. Congenital extremity and genital lymphedema is present in most patients.", "url": "https://disease-ontology.org/term/DOID:0060366", "evidence": [ { "id": "0060366", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060366" } ], "weight": 0.0 }, { "disease_id": "DOID:0080586", "name": "Van Maldergem syndrome 2", "description": "A Van Malergem syndrome that has_material_basis_in homozygous or compound heterozygous mutation in the FAT4 gene on chromosome 4q28.", "url": "https://disease-ontology.org/term/DOID:0080586", "evidence": [ { "id": "0080586", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080586" } ], "weight": 0.0 }, { "disease_id": "DOID:1289", "name": "neurodegenerative disease", "description": "A central nervous system disease that results in the progressive deterioration of function or structure of neurons.", "url": "https://disease-ontology.org/term/DOID:1289", "evidence": [ { "id": "1289", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1289" } ], "weight": 0.0 }, { "disease_id": "DOID:305", "name": "carcinoma", "description": "A cell type cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.", "url": "https://disease-ontology.org/term/DOID:305", "evidence": [ { "id": "305", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:305" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "biological_process": [ { "name": "nephron development", "id": "GO:0072006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072006", "evidence": [ { "database": "UniProtKB", "id": "D3ZEH1", "url": "https://www.uniprot.org/uniprotkb/D3ZEH1" } ], "pmid": "" }, { "name": "ossification involved in bone maturation", "id": "GO:0043931", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043931", "evidence": [ { "database": "UniProtKB", "id": "D3ZEH1", "url": "https://www.uniprot.org/uniprotkb/D3ZEH1" } ], "pmid": "" }, { "name": "condensed mesenchymal cell proliferation", "id": "GO:0072137", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072137", "evidence": [ { "database": "UniProtKB", "id": "D3ZEH1", "url": "https://www.uniprot.org/uniprotkb/D3ZEH1" } ], "pmid": "" }, { "name": "regulation of metanephric nephron tubule epithelial cell differentiation", "id": "GO:0072307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072307", "evidence": [ { "database": "UniProtKB", "id": "D3ZEH1", "url": "https://www.uniprot.org/uniprotkb/D3ZEH1" } ], "pmid": "" }, { "name": "plasma membrane organization", "id": "GO:0007009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007009", "evidence": [ { "database": "UniProtKB", "id": "D3ZEH1", "url": "https://www.uniprot.org/uniprotkb/D3ZEH1" } ], "pmid": "" }, { "name": "Notch signaling pathway", "id": "GO:0007219", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007219", "evidence": [ { "database": "UniProtKB", "id": "D3ZEH1", "url": "https://www.uniprot.org/uniprotkb/D3ZEH1" } ], "pmid": "" }, { "name": "axonogenesis", "id": "GO:0007409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007409", "evidence": [ { "database": "UniProtKB", "id": "D3ZEH1", "url": "https://www.uniprot.org/uniprotkb/D3ZEH1" } ], "pmid": "" }, { "name": "epithelial cell differentiation", "id": "GO:0030855", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030855", "evidence": [ { "database": "UniProtKB", "id": "D3ZEH1", "url": "https://www.uniprot.org/uniprotkb/D3ZEH1" } ], "pmid": "" }, { "name": "kidney development", "id": "GO:0001822", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001822", "evidence": [ { "database": "UniProtKB", "id": "D3ZEH1", "url": "https://www.uniprot.org/uniprotkb/D3ZEH1" } ], "pmid": "" }, { "name": "cerebral cortex development", "id": "GO:0021987", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021987", "evidence": [ { "database": "UniProtKB", "id": "D3ZEH1", "url": "https://www.uniprot.org/uniprotkb/D3ZEH1" } ], "pmid": "" }, { "name": "hippo signaling", "id": "GO:0035329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035329", "evidence": [ { "database": "UniProtKB", "id": "D3ZEH1", "url": "https://www.uniprot.org/uniprotkb/D3ZEH1" } ], "pmid": "" }, { "name": "heart morphogenesis", "id": "GO:0003007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003007", "evidence": [ { "database": "UniProtKB", "id": "D3ZEH1", "url": "https://www.uniprot.org/uniprotkb/D3ZEH1" } ], "pmid": "" }, { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "D3ZEH1", "url": "https://www.uniprot.org/uniprotkb/D3ZEH1" } ], "pmid": "" }, { "name": "heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules", "id": "GO:0007157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007157", "evidence": [ { "database": "UniProtKB", "id": "D3ZEH1", "url": "https://www.uniprot.org/uniprotkb/D3ZEH1" } ], "pmid": "" }, { "name": "digestive tract development", "id": "GO:0048565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048565", "evidence": [ { "database": "UniProtKB", "id": "D3ZEH1", "url": "https://www.uniprot.org/uniprotkb/D3ZEH1" } ], "pmid": "" }, { "name": "neurogenesis", "id": "GO:0022008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022008", "evidence": [ { "database": "UniProtKB", "id": "D3ZEH1", "url": "https://www.uniprot.org/uniprotkb/D3ZEH1" } ], "pmid": "" }, { "name": "branching involved in ureteric bud morphogenesis", "id": "GO:0001658", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001658", "evidence": [ { "database": "UniProtKB", "id": "D3ZEH1", "url": "https://www.uniprot.org/uniprotkb/D3ZEH1" } ], "pmid": "" }, { "name": "cell-cell adhesion mediated by cadherin", "id": "GO:0044331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044331", "evidence": [ { "database": "UniProtKB", "id": "D3ZEH1", "url": "https://www.uniprot.org/uniprotkb/D3ZEH1" } ], "pmid": "" }, { "name": "inner ear receptor cell stereocilium organization", "id": "GO:0060122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060122", "evidence": [ { "database": "UniProtKB", "id": "D3ZEH1", "url": "https://www.uniprot.org/uniprotkb/D3ZEH1" } ], "pmid": "" }, { "name": "fibroblast growth factor receptor signaling pathway", "id": "GO:0008543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008543", "evidence": [ { "database": "UniProtKB", "id": "D3ZEH1", "url": "https://www.uniprot.org/uniprotkb/D3ZEH1" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "D3ZEH1", "url": "https://www.uniprot.org/uniprotkb/D3ZEH1" } ], "pmid": "" }, { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "D3ZEH1", "url": "https://www.uniprot.org/uniprotkb/D3ZEH1" } ], "pmid": "" }, { "name": "apical part of cell", "id": "GO:0045177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045177", "evidence": [ { "database": "UniProtKB", "id": "D3ZEH1", "url": "https://www.uniprot.org/uniprotkb/D3ZEH1" } ], "pmid": "" } ], "molecular_function": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "D3ZEH1", "url": "https://www.uniprot.org/uniprotkb/D3ZEH1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "D3ZEH1-1", "start_pos": "2482", "end_pos": "2482", "site_lbl": "Thr2482", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2482, "start_aa": "Thr", "end_pos": 2482, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2482", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "D3ZEH1-1", "start_pos": "3490", "end_pos": "3490", "site_lbl": "Thr3490", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 3490, "start_aa": "Thr", "end_pos": 3490, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr3490", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "D3ZEH1-1", "start_pos": "4111", "end_pos": "4111", "site_lbl": "Thr4111", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 4111, "start_aa": "Thr", "end_pos": 4111, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr4111", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "D3ZEH1-1", "start_pos": "4908", "end_pos": "4908", "site_lbl": "Thr4908", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 4908, "start_aa": "Thr", "end_pos": 4908, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr4908", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "D3ZEH1-1" }, { "uniprot_canonical_ac": "D3ZEJ0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZEJ0", "url": "https://www.uniprot.org/uniprotkb/D3ZEJ0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 365, "chemical_mass": 40303.0, "gene_names": "Prdm12;Prdm12", "protein_name": "PR domain zinc finger protein 12", "disease": [ { "disease_id": "DOID:0070153", "name": "hereditary sensory and autonomic neuropathy type 8", "description": "A hereditary sensory and autonomic neuropathy characterized by congenital insensitivity to pain and decreased sweating and tear production that has_material_basis_in homozygous mutation in the PRDM12 gene on chromosome 9q34.", "url": "https://disease-ontology.org/term/DOID:0070153", "evidence": [ { "id": "0070153", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070153" } ], "weight": 0.0 } ], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "D3ZEJ0", "url": "https://www.uniprot.org/uniprotkb/D3ZEJ0" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "D3ZEJ0", "url": "https://www.uniprot.org/uniprotkb/D3ZEJ0" } ], "pmid": "" }, { "name": "neuron projection development", "id": "GO:0031175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031175", "evidence": [ { "database": "UniProtKB", "id": "D3ZEJ0", "url": "https://www.uniprot.org/uniprotkb/D3ZEJ0" } ], "pmid": "" }, { "name": "sensory perception of pain", "id": "GO:0019233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019233", "evidence": [ { "database": "UniProtKB", "id": "D3ZEJ0", "url": "https://www.uniprot.org/uniprotkb/D3ZEJ0" } ], "pmid": "" }, { "name": "detection of temperature stimulus involved in sensory perception of pain", "id": "GO:0050965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050965", "evidence": [ { "database": "UniProtKB", "id": "D3ZEJ0", "url": "https://www.uniprot.org/uniprotkb/D3ZEJ0" } ], "pmid": "" }, { "name": "protein methylation", "id": "GO:0006479", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006479", "evidence": [ { "database": "UniProtKB", "id": "D3ZEJ0", "url": "https://www.uniprot.org/uniprotkb/D3ZEJ0" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "D3ZEJ0", "url": "https://www.uniprot.org/uniprotkb/D3ZEJ0" } ], "pmid": "" }, { "name": "neurogenesis", "id": "GO:0022008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022008", "evidence": [ { "database": "UniProtKB", "id": "D3ZEJ0", "url": "https://www.uniprot.org/uniprotkb/D3ZEJ0" } ], "pmid": "" }, { "name": "neuron fate specification", "id": "GO:0048665", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048665", "evidence": [ { "database": "UniProtKB", "id": "D3ZEJ0", "url": "https://www.uniprot.org/uniprotkb/D3ZEJ0" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "D3ZEJ0", "url": "https://www.uniprot.org/uniprotkb/D3ZEJ0" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "D3ZEJ0", "url": "https://www.uniprot.org/uniprotkb/D3ZEJ0" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "D3ZEJ0", "url": "https://www.uniprot.org/uniprotkb/D3ZEJ0" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "D3ZEJ0", "url": "https://www.uniprot.org/uniprotkb/D3ZEJ0" } ], "pmid": "" }, { "name": "methyltransferase activity", "id": "GO:0008168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008168", "evidence": [ { "database": "UniProtKB", "id": "D3ZEJ0", "url": "https://www.uniprot.org/uniprotkb/D3ZEJ0" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "D3ZEJ0", "url": "https://www.uniprot.org/uniprotkb/D3ZEJ0" } ], "pmid": "" }, { "name": "histone methyltransferase binding", "id": "GO:1990226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990226", "evidence": [ { "database": "UniProtKB", "id": "D3ZEJ0", "url": "https://www.uniprot.org/uniprotkb/D3ZEJ0" } ], "pmid": "" }, { "name": "histone chaperone activity", "id": "GO:0140713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140713", "evidence": [ { "database": "UniProtKB", "id": "D3ZEJ0", "url": "https://www.uniprot.org/uniprotkb/D3ZEJ0" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D3ZEJ0", "url": "https://www.uniprot.org/uniprotkb/D3ZEJ0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZEJ0-1" }, { "uniprot_canonical_ac": "D3ZEK2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZEK2", "url": "https://www.uniprot.org/uniprotkb/D3ZEK2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 160, "chemical_mass": 18511.0, "gene_names": "Rpl21l3;AABR07026240.1;LOC108348409;Rpl21l3", "protein_name": "Large ribosomal subunit protein eL21", "disease": [], "biological_process": [ { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "D3ZEK2", "url": "https://www.uniprot.org/uniprotkb/D3ZEK2" } ], "pmid": "" } ], "molecular_function": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "D3ZEK2", "url": "https://www.uniprot.org/uniprotkb/D3ZEK2" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosolic large ribosomal subunit", "id": "GO:0022625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022625", "evidence": [ { "database": "UniProtKB", "id": "D3ZEK2", "url": "https://www.uniprot.org/uniprotkb/D3ZEK2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZEK2-1" }, { "uniprot_canonical_ac": "D3ZEK9-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZEK9", "url": "https://www.uniprot.org/uniprotkb/D3ZEK9" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 195, "chemical_mass": 20664.0, "gene_names": "Tcf15;Tcf15", "protein_name": "", "disease": [], "biological_process": [ { "name": "negative regulation of hematopoietic stem cell differentiation", "id": "GO:1902037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902037", "evidence": [ { "database": "UniProtKB", "id": "D3ZEK9", "url": "https://www.uniprot.org/uniprotkb/D3ZEK9" } ], "pmid": "" }, { "name": "respiratory system process", "id": "GO:0003016", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003016", "evidence": [ { "database": "UniProtKB", "id": "D3ZEK9", "url": "https://www.uniprot.org/uniprotkb/D3ZEK9" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "D3ZEK9", "url": "https://www.uniprot.org/uniprotkb/D3ZEK9" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "D3ZEK9", "url": "https://www.uniprot.org/uniprotkb/D3ZEK9" } ], "pmid": "" }, { "name": "establishment of epithelial cell apical/basal polarity", "id": "GO:0045198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045198", "evidence": [ { "database": "UniProtKB", "id": "D3ZEK9", "url": "https://www.uniprot.org/uniprotkb/D3ZEK9" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "D3ZEK9", "url": "https://www.uniprot.org/uniprotkb/D3ZEK9" } ], "pmid": "" }, { "name": "muscle organ development", "id": "GO:0007517", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007517", "evidence": [ { "database": "UniProtKB", "id": "D3ZEK9", "url": "https://www.uniprot.org/uniprotkb/D3ZEK9" } ], "pmid": "" }, { "name": "developmental process", "id": "GO:0032502", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032502", "evidence": [ { "database": "UniProtKB", "id": "D3ZEK9", "url": "https://www.uniprot.org/uniprotkb/D3ZEK9" } ], "pmid": "" }, { "name": "anterior/posterior pattern specification", "id": "GO:0009952", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009952", "evidence": [ { "database": "UniProtKB", "id": "D3ZEK9", "url": "https://www.uniprot.org/uniprotkb/D3ZEK9" } ], "pmid": "" }, { "name": "regulation of extracellular matrix organization", "id": "GO:1903053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903053", "evidence": [ { "database": "UniProtKB", "id": "D3ZEK9", "url": "https://www.uniprot.org/uniprotkb/D3ZEK9" } ], "pmid": "" }, { "name": "somitogenesis", "id": "GO:0001756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001756", "evidence": [ { "database": "UniProtKB", "id": "D3ZEK9", "url": "https://www.uniprot.org/uniprotkb/D3ZEK9" } ], "pmid": "" }, { "name": "stem cell population maintenance", "id": "GO:0019827", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019827", "evidence": [ { "database": "UniProtKB", "id": "D3ZEK9", "url": "https://www.uniprot.org/uniprotkb/D3ZEK9" } ], "pmid": "" }, { "name": "skeletal system morphogenesis", "id": "GO:0048705", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048705", "evidence": [ { "database": "UniProtKB", "id": "D3ZEK9", "url": "https://www.uniprot.org/uniprotkb/D3ZEK9" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "D3ZEK9", "url": "https://www.uniprot.org/uniprotkb/D3ZEK9" } ], "pmid": "" }, { "name": "muscle organ morphogenesis", "id": "GO:0048644", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048644", "evidence": [ { "database": "UniProtKB", "id": "D3ZEK9", "url": "https://www.uniprot.org/uniprotkb/D3ZEK9" } ], "pmid": "" }, { "name": "ear development", "id": "GO:0043583", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043583", "evidence": [ { "database": "UniProtKB", "id": "D3ZEK9", "url": "https://www.uniprot.org/uniprotkb/D3ZEK9" } ], "pmid": "" }, { "name": "neuromuscular process controlling posture", "id": "GO:0050884", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050884", "evidence": [ { "database": "UniProtKB", "id": "D3ZEK9", "url": "https://www.uniprot.org/uniprotkb/D3ZEK9" } ], "pmid": "" }, { "name": "positive regulation of stem cell differentiation", "id": "GO:2000738", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000738", "evidence": [ { "database": "UniProtKB", "id": "D3ZEK9", "url": "https://www.uniprot.org/uniprotkb/D3ZEK9" } ], "pmid": "" }, { "name": "paraxial mesoderm development", "id": "GO:0048339", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048339", "evidence": [ { "database": "UniProtKB", "id": "D3ZEK9", "url": "https://www.uniprot.org/uniprotkb/D3ZEK9" } ], "pmid": "" }, { "name": "mesenchymal to epithelial transition", "id": "GO:0060231", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060231", "evidence": [ { "database": "UniProtKB", "id": "D3ZEK9", "url": "https://www.uniprot.org/uniprotkb/D3ZEK9" } ], "pmid": "" }, { "name": "post-anal tail morphogenesis", "id": "GO:0036342", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036342", "evidence": [ { "database": "UniProtKB", "id": "D3ZEK9", "url": "https://www.uniprot.org/uniprotkb/D3ZEK9" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D3ZEK9", "url": "https://www.uniprot.org/uniprotkb/D3ZEK9" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "D3ZEK9", "url": "https://www.uniprot.org/uniprotkb/D3ZEK9" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulator complex", "id": "GO:0090575", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090575", "evidence": [ { "database": "UniProtKB", "id": "D3ZEK9", "url": "https://www.uniprot.org/uniprotkb/D3ZEK9" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "D3ZEK9", "url": "https://www.uniprot.org/uniprotkb/D3ZEK9" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "D3ZEK9", "url": "https://www.uniprot.org/uniprotkb/D3ZEK9" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "D3ZEK9", "url": "https://www.uniprot.org/uniprotkb/D3ZEK9" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "D3ZEK9", "url": "https://www.uniprot.org/uniprotkb/D3ZEK9" } ], "pmid": "" }, { "name": "E-box binding", "id": "GO:0070888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070888", "evidence": [ { "database": "UniProtKB", "id": "D3ZEK9", "url": "https://www.uniprot.org/uniprotkb/D3ZEK9" } ], "pmid": "" }, { "name": "bHLH transcription factor binding", "id": "GO:0043425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043425", "evidence": [ { "database": "UniProtKB", "id": "D3ZEK9", "url": "https://www.uniprot.org/uniprotkb/D3ZEK9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZEK9-1" }, { "uniprot_canonical_ac": "D3ZEP8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZEP8", "url": "https://www.uniprot.org/uniprotkb/D3ZEP8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 798, "chemical_mass": 88002.0, "gene_names": "Adam32", "protein_name": "", "disease": [], "molecular_function": [ { "name": "metalloendopeptidase activity", "id": "GO:0004222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004222", "evidence": [ { "database": "UniProtKB", "id": "D3ZEP8", "url": "https://www.uniprot.org/uniprotkb/D3ZEP8" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "D3ZEP8", "url": "https://www.uniprot.org/uniprotkb/D3ZEP8" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "D3ZEP8", "url": "https://www.uniprot.org/uniprotkb/D3ZEP8" } ], "pmid": "" }, { "name": "sperm principal piece", "id": "GO:0097228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097228", "evidence": [ { "database": "UniProtKB", "id": "D3ZEP8", "url": "https://www.uniprot.org/uniprotkb/D3ZEP8" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "D3ZEP8", "url": "https://www.uniprot.org/uniprotkb/D3ZEP8" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "D3ZEP8", "url": "https://www.uniprot.org/uniprotkb/D3ZEP8" } ], "pmid": "" }, { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "D3ZEP8", "url": "https://www.uniprot.org/uniprotkb/D3ZEP8" } ], "pmid": "" }, { "name": "binding of sperm to zona pellucida", "id": "GO:0007339", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007339", "evidence": [ { "database": "UniProtKB", "id": "D3ZEP8", "url": "https://www.uniprot.org/uniprotkb/D3ZEP8" } ], "pmid": "" }, { "name": "male gonad development", "id": "GO:0008584", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008584", "evidence": [ { "database": "UniProtKB", "id": "D3ZEP8", "url": "https://www.uniprot.org/uniprotkb/D3ZEP8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZEP8-1" }, { "uniprot_canonical_ac": "D3ZEU8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZEU8", "url": "https://www.uniprot.org/uniprotkb/D3ZEU8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 319, "chemical_mass": 36330.0, "gene_names": "Fam76a", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "D3ZEU8", "url": "https://www.uniprot.org/uniprotkb/D3ZEU8" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "D3ZEU8", "url": "https://www.uniprot.org/uniprotkb/D3ZEU8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZEU8-1" }, { "uniprot_canonical_ac": "D3ZEY0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZEY0", "url": "https://www.uniprot.org/uniprotkb/D3ZEY0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1530, "chemical_mass": 173504.0, "gene_names": "Ccdc141;CAMDI;Ccdc141", "protein_name": "Coiled-coil domain-containing protein 141", "disease": [], "biological_process": [ { "name": "cerebral cortex radially oriented cell migration", "id": "GO:0021799", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021799", "evidence": [ { "database": "UniProtKB", "id": "D3ZEY0", "url": "https://www.uniprot.org/uniprotkb/D3ZEY0" } ], "pmid": "" }, { "name": "brain development", "id": "GO:0007420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420", "evidence": [ { "database": "UniProtKB", "id": "D3ZEY0", "url": "https://www.uniprot.org/uniprotkb/D3ZEY0" } ], "pmid": "" }, { "name": "regulation of synapse assembly", "id": "GO:0051963", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051963", "evidence": [ { "database": "UniProtKB", "id": "D3ZEY0", "url": "https://www.uniprot.org/uniprotkb/D3ZEY0" } ], "pmid": "" }, { "name": "heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules", "id": "GO:0007157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007157", "evidence": [ { "database": "UniProtKB", "id": "D3ZEY0", "url": "https://www.uniprot.org/uniprotkb/D3ZEY0" } ], "pmid": "" }, { "name": "centrosome localization", "id": "GO:0051642", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051642", "evidence": [ { "database": "UniProtKB", "id": "D3ZEY0", "url": "https://www.uniprot.org/uniprotkb/D3ZEY0" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "D3ZEY0", "url": "https://www.uniprot.org/uniprotkb/D3ZEY0" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "D3ZEY0", "url": "https://www.uniprot.org/uniprotkb/D3ZEY0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "D3ZEY0", "url": "https://www.uniprot.org/uniprotkb/D3ZEY0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "D3ZEY0-1", "start_pos": "1060", "end_pos": "1060", "site_lbl": "Thr1060", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1060, "start_aa": "Thr", "end_pos": 1060, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1060", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "D3ZEY0-1", "start_pos": "91", "end_pos": "91", "site_lbl": "Thr91", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "D3ZEY0", "url": "https://www.uniprot.org/uniprotkb/D3ZEY0" } ] } ] } ], "record_id": "D3ZEY0-1" }, { "uniprot_canonical_ac": "D3ZF41-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZF41", "url": "https://www.uniprot.org/uniprotkb/D3ZF41" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 2568, "chemical_mass": 274120.0, "gene_names": "Zfhx2", "protein_name": "", "disease": [ { "disease_id": "DOID:0050957", "name": "spinocerebellar ataxia 4", "description": "An autosomal dominant cerebellar ataxia that is characterized by progressive ataxia, dysarthria and peripheral neuropathy that has_material_basis_in heterozygous trinucleotide repeat expansion (GGCn) in the ZFHX3 gene on chromosome 16q22.", "url": "https://disease-ontology.org/term/DOID:0050957", "evidence": [ { "id": "0050957", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050957" } ], "weight": 0.0 }, { "disease_id": "DOID:0081075", "name": "Marsili syndrome", "description": "A syndrome that is characterized by a lowered ability to sense pain, to experience temperature, and to sweat and that has_material_basis_in heterozygous mutation in the ZFHX2 gene on chromosome 14q11.", "url": "https://disease-ontology.org/term/DOID:0081075", "evidence": [ { "id": "0081075", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081075" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D3ZF41", "url": "https://www.uniprot.org/uniprotkb/D3ZF41" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "D3ZF41", "url": "https://www.uniprot.org/uniprotkb/D3ZF41" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "D3ZF41", "url": "https://www.uniprot.org/uniprotkb/D3ZF41" } ], "pmid": "" }, { "name": "adult behavior", "id": "GO:0030534", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030534", "evidence": [ { "database": "UniProtKB", "id": "D3ZF41", "url": "https://www.uniprot.org/uniprotkb/D3ZF41" } ], "pmid": "" }, { "name": "regulation of sensory perception of pain", "id": "GO:0051930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051930", "evidence": [ { "database": "UniProtKB", "id": "D3ZF41", "url": "https://www.uniprot.org/uniprotkb/D3ZF41" } ], "pmid": "" }, { "name": "regulation of neuron differentiation", "id": "GO:0045664", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045664", "evidence": [ { "database": "UniProtKB", "id": "D3ZF41", "url": "https://www.uniprot.org/uniprotkb/D3ZF41" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "D3ZF41", "url": "https://www.uniprot.org/uniprotkb/D3ZF41" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "D3ZF41", "url": "https://www.uniprot.org/uniprotkb/D3ZF41" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "D3ZF41", "url": "https://www.uniprot.org/uniprotkb/D3ZF41" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "D3ZF41", "url": "https://www.uniprot.org/uniprotkb/D3ZF41" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "D3ZF41-1", "start_pos": "1473", "end_pos": "1473", "site_lbl": "Thr1473", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1473, "start_aa": "Thr", "end_pos": 1473, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1473", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "D3ZF41-1", "start_pos": "1933", "end_pos": "1933", "site_lbl": "Thr1933", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1933, "start_aa": "Thr", "end_pos": 1933, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1933", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "D3ZF41-1", "start_pos": "1971", "end_pos": "1971", "site_lbl": "Thr1971", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1971, "start_aa": "Thr", "end_pos": 1971, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1971", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "D3ZF41-1", "start_pos": "1992", "end_pos": "1992", "site_lbl": "Thr1992", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1992, "start_aa": "Thr", "end_pos": 1992, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1992", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "D3ZF41-1", "start_pos": "2208", "end_pos": "2208", "site_lbl": "Thr2208", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2208, "start_aa": "Thr", "end_pos": 2208, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2208", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "D3ZF41-1", "start_pos": "351", "end_pos": "351", "site_lbl": "Thr351", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 351, "start_aa": "Thr", "end_pos": 351, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr351", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "D3ZF41-1" }, { "uniprot_canonical_ac": "D3ZFA7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZFA7", "url": "https://www.uniprot.org/uniprotkb/D3ZFA7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 504, "chemical_mass": 57465.0, "gene_names": "Nr1h5;Nr1h5", "protein_name": "", "disease": [], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "D3ZFA7", "url": "https://www.uniprot.org/uniprotkb/D3ZFA7" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "D3ZFA7", "url": "https://www.uniprot.org/uniprotkb/D3ZFA7" } ], "pmid": "" }, { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "D3ZFA7", "url": "https://www.uniprot.org/uniprotkb/D3ZFA7" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "D3ZFA7", "url": "https://www.uniprot.org/uniprotkb/D3ZFA7" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "D3ZFA7", "url": "https://www.uniprot.org/uniprotkb/D3ZFA7" } ], "pmid": "" }, { "name": "negative regulation of inflammatory response", "id": "GO:0050728", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050728", "evidence": [ { "database": "UniProtKB", "id": "D3ZFA7", "url": "https://www.uniprot.org/uniprotkb/D3ZFA7" } ], "pmid": "" }, { "name": "cholesterol homeostasis", "id": "GO:0042632", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042632", "evidence": [ { "database": "UniProtKB", "id": "D3ZFA7", "url": "https://www.uniprot.org/uniprotkb/D3ZFA7" } ], "pmid": "" }, { "name": "intracellular receptor signaling pathway", "id": "GO:0030522", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030522", "evidence": [ { "database": "UniProtKB", "id": "D3ZFA7", "url": "https://www.uniprot.org/uniprotkb/D3ZFA7" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D3ZFA7", "url": "https://www.uniprot.org/uniprotkb/D3ZFA7" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulator complex", "id": "GO:0090575", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090575", "evidence": [ { "database": "UniProtKB", "id": "D3ZFA7", "url": "https://www.uniprot.org/uniprotkb/D3ZFA7" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "D3ZFA7", "url": "https://www.uniprot.org/uniprotkb/D3ZFA7" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "D3ZFA7", "url": "https://www.uniprot.org/uniprotkb/D3ZFA7" } ], "pmid": "" }, { "name": "nuclear receptor activity", "id": "GO:0004879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004879", "evidence": [ { "database": "UniProtKB", "id": "D3ZFA7", "url": "https://www.uniprot.org/uniprotkb/D3ZFA7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZFA7-1" }, { "uniprot_canonical_ac": "D3ZFB7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZFB7", "url": "https://www.uniprot.org/uniprotkb/D3ZFB7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 314, "chemical_mass": 36002.0, "gene_names": "Or6c216;Olr1055;Or6c216;ratchr7-7861520-7860576_ORF", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "D3ZFB7", "url": "https://www.uniprot.org/uniprotkb/D3ZFB7" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "D3ZFB7", "url": "https://www.uniprot.org/uniprotkb/D3ZFB7" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "D3ZFB7", "url": "https://www.uniprot.org/uniprotkb/D3ZFB7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZFB7-1" }, { "uniprot_canonical_ac": "D3ZFC8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZFC8", "url": "https://www.uniprot.org/uniprotkb/D3ZFC8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 216, "chemical_mass": 26308.0, "gene_names": "Efcab9;Efcab9;LOC100911628", "protein_name": "", "disease": [], "cellular_component": [ { "name": "CatSper complex", "id": "GO:0036128", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036128", "evidence": [ { "database": "UniProtKB", "id": "D3ZFC8", "url": "https://www.uniprot.org/uniprotkb/D3ZFC8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "D3ZFC8", "url": "https://www.uniprot.org/uniprotkb/D3ZFC8" } ], "pmid": "" }, { "name": "sperm principal piece", "id": "GO:0097228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097228", "evidence": [ { "database": "UniProtKB", "id": "D3ZFC8", "url": "https://www.uniprot.org/uniprotkb/D3ZFC8" } ], "pmid": "" } ], "biological_process": [ { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "D3ZFC8", "url": "https://www.uniprot.org/uniprotkb/D3ZFC8" } ], "pmid": "" }, { "name": "flagellated sperm motility", "id": "GO:0030317", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030317", "evidence": [ { "database": "UniProtKB", "id": "D3ZFC8", "url": "https://www.uniprot.org/uniprotkb/D3ZFC8" } ], "pmid": "" }, { "name": "sperm capacitation", "id": "GO:0048240", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048240", "evidence": [ { "database": "UniProtKB", "id": "D3ZFC8", "url": "https://www.uniprot.org/uniprotkb/D3ZFC8" } ], "pmid": "" } ], "molecular_function": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "D3ZFC8", "url": "https://www.uniprot.org/uniprotkb/D3ZFC8" } ], "pmid": "" }, { "name": "calcium ion sensor activity", "id": "GO:0061891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061891", "evidence": [ { "database": "UniProtKB", "id": "D3ZFC8", "url": "https://www.uniprot.org/uniprotkb/D3ZFC8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZFC8-1" }, { "uniprot_canonical_ac": "D3ZFT4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZFT4", "url": "https://www.uniprot.org/uniprotkb/D3ZFT4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 311, "chemical_mass": 35118.0, "gene_names": "Or51b4b;Olr129;Or51b4b", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "D3ZFT4", "url": "https://www.uniprot.org/uniprotkb/D3ZFT4" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "D3ZFT4", "url": "https://www.uniprot.org/uniprotkb/D3ZFT4" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "D3ZFT4", "url": "https://www.uniprot.org/uniprotkb/D3ZFT4" } ], "pmid": "" } ], "biological_process": [ { "name": "cellular response to lipid", "id": "GO:0071396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071396", "evidence": [ { "database": "UniProtKB", "id": "D3ZFT4", "url": "https://www.uniprot.org/uniprotkb/D3ZFT4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZFT4-1" }, { "uniprot_canonical_ac": "D3ZG74-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZG74", "url": "https://www.uniprot.org/uniprotkb/D3ZG74" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 3224, "chemical_mass": 357377.0, "gene_names": "Frem2", "protein_name": "FRAS1-related extracellular matrix protein 2", "disease": [ { "disease_id": "DOID:0090001", "name": "Fraser syndrome", "description": "A syndrome characterized by cryptophthalmos, syndactyly, ambiguous genitalia, laryngeal and genitourinary malformations, oral clefting, and mental retardation that has_material_basis_in homozygous or compound heterozygous mutation in the FRAS1 gene on chromosome 4q21, the FREM2 gene on chromosome 13q13, or the GRIP1 gene on chromosome 12q14.", "url": "https://disease-ontology.org/term/DOID:0090001", "evidence": [ { "id": "0090001", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0090001" } ], "weight": 0.0 }, { "disease_id": "DOID:0111407", "name": "Fraser syndrome 2", "description": "A Fraser syndrome that has_material_basis_in homozygous or compound heterozygous mutation in the FREM2 gene on chromosome 13q13.3.", "url": "https://disease-ontology.org/term/DOID:0111407", "evidence": [ { "id": "0111407", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111407" } ], "weight": 0.0 }, { "disease_id": "DOID:0111717", "name": "isolated cryptophthalmia", "description": "A cryptophthalmia characterized by absence of the eyelids with skin covering the eye and often an underlying malformed eye.", "url": "https://disease-ontology.org/term/DOID:0111717", "evidence": [ { "id": "0111717", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111717" } ], "weight": 0.0 } ], "biological_process": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "D3ZG74", "url": "https://www.uniprot.org/uniprotkb/D3ZG74" } ], "pmid": "" }, { "name": "heart development", "id": "GO:0007507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007507", "evidence": [ { "database": "UniProtKB", "id": "D3ZG74", "url": "https://www.uniprot.org/uniprotkb/D3ZG74" } ], "pmid": "" }, { "name": "kidney development", "id": "GO:0001822", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001822", "evidence": [ { "database": "UniProtKB", "id": "D3ZG74", "url": "https://www.uniprot.org/uniprotkb/D3ZG74" } ], "pmid": "" }, { "name": "cell-matrix adhesion", "id": "GO:0007160", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007160", "evidence": [ { "database": "UniProtKB", "id": "D3ZG74", "url": "https://www.uniprot.org/uniprotkb/D3ZG74" } ], "pmid": "" }, { "name": "cell communication", "id": "GO:0007154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007154", "evidence": [ { "database": "UniProtKB", "id": "D3ZG74", "url": "https://www.uniprot.org/uniprotkb/D3ZG74" } ], "pmid": "" }, { "name": "embryonic digit morphogenesis", "id": "GO:0042733", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042733", "evidence": [ { "database": "UniProtKB", "id": "D3ZG74", "url": "https://www.uniprot.org/uniprotkb/D3ZG74" } ], "pmid": "" }, { "name": "inner ear development", "id": "GO:0048839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048839", "evidence": [ { "database": "UniProtKB", "id": "D3ZG74", "url": "https://www.uniprot.org/uniprotkb/D3ZG74" } ], "pmid": "" }, { "name": "epithelial structure maintenance", "id": "GO:0010669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010669", "evidence": [ { "database": "UniProtKB", "id": "D3ZG74", "url": "https://www.uniprot.org/uniprotkb/D3ZG74" } ], "pmid": "" }, { "name": "eye development", "id": "GO:0001654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001654", "evidence": [ { "database": "UniProtKB", "id": "D3ZG74", "url": "https://www.uniprot.org/uniprotkb/D3ZG74" } ], "pmid": "" }, { "name": "morphogenesis of an epithelium", "id": "GO:0002009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002009", "evidence": [ { "database": "UniProtKB", "id": "D3ZG74", "url": "https://www.uniprot.org/uniprotkb/D3ZG74" } ], "pmid": "" } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "D3ZG74", "url": "https://www.uniprot.org/uniprotkb/D3ZG74" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "D3ZG74", "url": "https://www.uniprot.org/uniprotkb/D3ZG74" } ], "pmid": "" }, { "name": "basement membrane", "id": "GO:0005604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005604", "evidence": [ { "database": "UniProtKB", "id": "D3ZG74", "url": "https://www.uniprot.org/uniprotkb/D3ZG74" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "D3ZG74", "url": "https://www.uniprot.org/uniprotkb/D3ZG74" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "D3ZG74-1", "start_pos": "1164", "end_pos": "1164", "site_lbl": "Thr1164", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1164, "start_aa": "Thr", "end_pos": 1164, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1164", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "D3ZG74-1" }, { "uniprot_canonical_ac": "D3ZGE8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZGE8", "url": "https://www.uniprot.org/uniprotkb/D3ZGE8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 313, "chemical_mass": 36060.0, "gene_names": "LOC134482366;LOC134482366;YJU2", "protein_name": "Splicing factor YJU2", "disease": [], "biological_process": [ { "name": "generation of catalytic spliceosome for first transesterification step", "id": "GO:0000349", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000349", "evidence": [ { "database": "UniProtKB", "id": "D3ZGE8", "url": "https://www.uniprot.org/uniprotkb/D3ZGE8" } ], "pmid": "" }, { "name": "mRNA cis splicing, via spliceosome", "id": "GO:0045292", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045292", "evidence": [ { "database": "UniProtKB", "id": "D3ZGE8", "url": "https://www.uniprot.org/uniprotkb/D3ZGE8" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "D3ZGE8", "url": "https://www.uniprot.org/uniprotkb/D3ZGE8" } ], "pmid": "" } ], "cellular_component": [ { "name": "U2-type catalytic step 1 spliceosome", "id": "GO:0071006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071006", "evidence": [ { "database": "UniProtKB", "id": "D3ZGE8", "url": "https://www.uniprot.org/uniprotkb/D3ZGE8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZGE8-1" }, { "uniprot_canonical_ac": "D3ZGQ0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZGQ0", "url": "https://www.uniprot.org/uniprotkb/D3ZGQ0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 740, "chemical_mass": 82431.0, "gene_names": "Il17rd;Il17rd;RGD1565237", "protein_name": "Interleukin-17 receptor D", "disease": [ { "disease_id": "DOID:0090076", "name": "hypogonadotropic hypogonadism 18 with or without anosmia", "description": "A hypogonadotropic hypogonadism that has_material_basis_in heterozygous or homozygous mutation in the IL17RD gene on chromosome 3p14, sometimes in association with mutation in other genes.", "url": "https://disease-ontology.org/term/DOID:0090076", "evidence": [ { "id": "0090076", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0090076" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "D3ZGQ0", "url": "https://www.uniprot.org/uniprotkb/D3ZGQ0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "D3ZGQ0", "url": "https://www.uniprot.org/uniprotkb/D3ZGQ0" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of transforming growth factor beta receptor signaling pathway", "id": "GO:0030512", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030512", "evidence": [ { "database": "UniProtKB", "id": "D3ZGQ0", "url": "https://www.uniprot.org/uniprotkb/D3ZGQ0" } ], "pmid": "" }, { "name": "negative regulation of epithelial to mesenchymal transition", "id": "GO:0010719", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010719", "evidence": [ { "database": "UniProtKB", "id": "D3ZGQ0", "url": "https://www.uniprot.org/uniprotkb/D3ZGQ0" } ], "pmid": "" } ], "molecular_function": [ { "name": "interleukin-17 receptor activity", "id": "GO:0030368", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030368", "evidence": [ { "database": "UniProtKB", "id": "D3ZGQ0", "url": "https://www.uniprot.org/uniprotkb/D3ZGQ0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZGQ0-1" }, { "uniprot_canonical_ac": "D3ZGU4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZGU4", "url": "https://www.uniprot.org/uniprotkb/D3ZGU4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 319, "chemical_mass": 35392.0, "gene_names": "Or5a21;Olr332;Or5a21;ratchr1-215397764-215396805_ORF", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "D3ZGU4", "url": "https://www.uniprot.org/uniprotkb/D3ZGU4" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "D3ZGU4", "url": "https://www.uniprot.org/uniprotkb/D3ZGU4" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "D3ZGU4", "url": "https://www.uniprot.org/uniprotkb/D3ZGU4" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "D3ZGU4", "url": "https://www.uniprot.org/uniprotkb/D3ZGU4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZGU4-1" }, { "uniprot_canonical_ac": "D3ZGW2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZGW2", "url": "https://www.uniprot.org/uniprotkb/D3ZGW2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 628, "chemical_mass": 66080.0, "gene_names": "Ap1g2", "protein_name": "Junctophilin", "disease": [], "cellular_component": [ { "name": "smooth endoplasmic reticulum", "id": "GO:0005790", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005790", "evidence": [ { "database": "UniProtKB", "id": "D3ZGW2", "url": "https://www.uniprot.org/uniprotkb/D3ZGW2" } ], "pmid": "" }, { "name": "Golgi-associated vesicle", "id": "GO:0005798", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005798", "evidence": [ { "database": "UniProtKB", "id": "D3ZGW2", "url": "https://www.uniprot.org/uniprotkb/D3ZGW2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "D3ZGW2", "url": "https://www.uniprot.org/uniprotkb/D3ZGW2" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "D3ZGW2", "url": "https://www.uniprot.org/uniprotkb/D3ZGW2" } ], "pmid": "" }, { "name": "dendritic shaft", "id": "GO:0043198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043198", "evidence": [ { "database": "UniProtKB", "id": "D3ZGW2", "url": "https://www.uniprot.org/uniprotkb/D3ZGW2" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "D3ZGW2", "url": "https://www.uniprot.org/uniprotkb/D3ZGW2" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "D3ZGW2", "url": "https://www.uniprot.org/uniprotkb/D3ZGW2" } ], "pmid": "" }, { "name": "transport vesicle", "id": "GO:0030133", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030133", "evidence": [ { "database": "UniProtKB", "id": "D3ZGW2", "url": "https://www.uniprot.org/uniprotkb/D3ZGW2" } ], "pmid": "" }, { "name": "AP-1 adaptor complex", "id": "GO:0030121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030121", "evidence": [ { "database": "UniProtKB", "id": "D3ZGW2", "url": "https://www.uniprot.org/uniprotkb/D3ZGW2" } ], "pmid": "" }, { "name": "junctional membrane complex", "id": "GO:0030314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030314", "evidence": [ { "database": "UniProtKB", "id": "D3ZGW2", "url": "https://www.uniprot.org/uniprotkb/D3ZGW2" } ], "pmid": "" } ], "molecular_function": [ { "name": "clathrin adaptor activity", "id": "GO:0035615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035615", "evidence": [ { "database": "UniProtKB", "id": "D3ZGW2", "url": "https://www.uniprot.org/uniprotkb/D3ZGW2" } ], "pmid": "" } ], "biological_process": [ { "name": "Golgi to vacuole transport", "id": "GO:0006896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006896", "evidence": [ { "database": "UniProtKB", "id": "D3ZGW2", "url": "https://www.uniprot.org/uniprotkb/D3ZGW2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "D3ZGW2-1", "start_pos": "172", "end_pos": "172", "site_lbl": "Thr172", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 172, "start_aa": "Thr", "end_pos": 172, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr172", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "D3ZGW2-1" }, { "uniprot_canonical_ac": "D3ZH36-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZH36", "url": "https://www.uniprot.org/uniprotkb/D3ZH36" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 820, "chemical_mass": 89960.0, "gene_names": "Elfn2;Elfn2-ps1;Elfn2;LOC100910536;RGD1559693", "protein_name": "", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "D3ZH36", "url": "https://www.uniprot.org/uniprotkb/D3ZH36" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "D3ZH36", "url": "https://www.uniprot.org/uniprotkb/D3ZH36" } ], "pmid": "" }, { "name": "postsynaptic density membrane", "id": "GO:0098839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098839", "evidence": [ { "database": "UniProtKB", "id": "D3ZH36", "url": "https://www.uniprot.org/uniprotkb/D3ZH36" } ], "pmid": "" } ], "biological_process": [ { "name": "chemical synaptic transmission", "id": "GO:0007268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007268", "evidence": [ { "database": "UniProtKB", "id": "D3ZH36", "url": "https://www.uniprot.org/uniprotkb/D3ZH36" } ], "pmid": "" }, { "name": "establishment of protein localization", "id": "GO:0045184", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045184", "evidence": [ { "database": "UniProtKB", "id": "D3ZH36", "url": "https://www.uniprot.org/uniprotkb/D3ZH36" } ], "pmid": "" }, { "name": "synaptic membrane adhesion", "id": "GO:0099560", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099560", "evidence": [ { "database": "UniProtKB", "id": "D3ZH36", "url": "https://www.uniprot.org/uniprotkb/D3ZH36" } ], "pmid": "" }, { "name": "gene expression", "id": "GO:0010467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010467", "evidence": [ { "database": "UniProtKB", "id": "D3ZH36", "url": "https://www.uniprot.org/uniprotkb/D3ZH36" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein phosphatase inhibitor activity", "id": "GO:0004864", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004864", "evidence": [ { "database": "UniProtKB", "id": "D3ZH36", "url": "https://www.uniprot.org/uniprotkb/D3ZH36" } ], "pmid": "" }, { "name": "signaling receptor activity", "id": "GO:0038023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038023", "evidence": [ { "database": "UniProtKB", "id": "D3ZH36", "url": "https://www.uniprot.org/uniprotkb/D3ZH36" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "D3ZH36-1", "start_pos": "592", "end_pos": "592", "site_lbl": "Thr592", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 592, "start_aa": "Thr", "end_pos": 592, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr592", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "D3ZH36-1" }, { "uniprot_canonical_ac": "D3ZH42-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZH42", "url": "https://www.uniprot.org/uniprotkb/D3ZH42" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1283, "chemical_mass": 142998.0, "gene_names": "Mov10l1;Mov10l1", "protein_name": "RNA helicase Mov10l1", "disease": [ { "disease_id": "DOID:0070572", "name": "spermatogenic failure 73", "description": "A spermatogenic failure characterized by nonobstructive azoospermia due to meiotic arrest that has_material_basis_in homozygous or compound heterozygous mutation in the MOV10L1 gene on chromosome 22q13.33.", "url": "https://disease-ontology.org/term/DOID:0070572", "evidence": [ { "id": "0070572", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070572" } ], "weight": 0.0 }, { "disease_id": "DOID:5426", "name": "primary ovarian insufficiency", "description": "An ovarian disease where ovaries do not produce estrogen despite high levels of circulating gonadotropins in women under 40.", "url": "https://disease-ontology.org/term/DOID:5426", "evidence": [ { "id": "5426", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5426" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "D3ZH42", "url": "https://www.uniprot.org/uniprotkb/D3ZH42" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "D3ZH42", "url": "https://www.uniprot.org/uniprotkb/D3ZH42" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "D3ZH42", "url": "https://www.uniprot.org/uniprotkb/D3ZH42" } ], "pmid": "" }, { "name": "piRNA binding", "id": "GO:0034584", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034584", "evidence": [ { "database": "UniProtKB", "id": "D3ZH42", "url": "https://www.uniprot.org/uniprotkb/D3ZH42" } ], "pmid": "" }, { "name": "RNA helicase activity", "id": "GO:0003724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003724", "evidence": [ { "database": "UniProtKB", "id": "D3ZH42", "url": "https://www.uniprot.org/uniprotkb/D3ZH42" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "D3ZH42", "url": "https://www.uniprot.org/uniprotkb/D3ZH42" } ], "pmid": "" }, { "name": "pi-body", "id": "GO:0071546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071546", "evidence": [ { "database": "UniProtKB", "id": "D3ZH42", "url": "https://www.uniprot.org/uniprotkb/D3ZH42" } ], "pmid": "" }, { "name": "P granule", "id": "GO:0043186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043186", "evidence": [ { "database": "UniProtKB", "id": "D3ZH42", "url": "https://www.uniprot.org/uniprotkb/D3ZH42" } ], "pmid": "" } ], "biological_process": [ { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "D3ZH42", "url": "https://www.uniprot.org/uniprotkb/D3ZH42" } ], "pmid": "" }, { "name": "germ cell development", "id": "GO:0007281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007281", "evidence": [ { "database": "UniProtKB", "id": "D3ZH42", "url": "https://www.uniprot.org/uniprotkb/D3ZH42" } ], "pmid": "" }, { "name": "male meiotic nuclear division", "id": "GO:0007140", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007140", "evidence": [ { "database": "UniProtKB", "id": "D3ZH42", "url": "https://www.uniprot.org/uniprotkb/D3ZH42" } ], "pmid": "" }, { "name": "regulatory ncRNA-mediated post-transcriptional gene silencing", "id": "GO:0035194", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035194", "evidence": [ { "database": "UniProtKB", "id": "D3ZH42", "url": "https://www.uniprot.org/uniprotkb/D3ZH42" } ], "pmid": "" }, { "name": "negative regulation of cell cycle", "id": "GO:0045786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045786", "evidence": [ { "database": "UniProtKB", "id": "D3ZH42", "url": "https://www.uniprot.org/uniprotkb/D3ZH42" } ], "pmid": "" }, { "name": "piRNA processing", "id": "GO:0034587", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034587", "evidence": [ { "database": "UniProtKB", "id": "D3ZH42", "url": "https://www.uniprot.org/uniprotkb/D3ZH42" } ], "pmid": "" }, { "name": "male meiosis I", "id": "GO:0007141", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007141", "evidence": [ { "database": "UniProtKB", "id": "D3ZH42", "url": "https://www.uniprot.org/uniprotkb/D3ZH42" } ], "pmid": "" }, { "name": "transposable element silencing by piRNA-mediated DNA methylation", "id": "GO:0141196", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141196", "evidence": [ { "database": "UniProtKB", "id": "D3ZH42", "url": "https://www.uniprot.org/uniprotkb/D3ZH42" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZH42-1" }, { "uniprot_canonical_ac": "D3ZH49-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZH49", "url": "https://www.uniprot.org/uniprotkb/D3ZH49" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 316, "chemical_mass": 36021.0, "gene_names": "Or6c68;Olr1006;Or6c68;ratchr7-6593123-6592173_ORF", "protein_name": "", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "D3ZH49", "url": "https://www.uniprot.org/uniprotkb/D3ZH49" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "D3ZH49", "url": "https://www.uniprot.org/uniprotkb/D3ZH49" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "D3ZH49", "url": "https://www.uniprot.org/uniprotkb/D3ZH49" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZH49-1" }, { "uniprot_canonical_ac": "D3ZH78-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZH78", "url": "https://www.uniprot.org/uniprotkb/D3ZH78" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 455, "chemical_mass": 47099.0, "gene_names": "Gprin2;Gprin2;RGD1308922", "protein_name": "", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "D3ZH78", "url": "https://www.uniprot.org/uniprotkb/D3ZH78" } ], "pmid": "" } ], "biological_process": [ { "name": "neuron projection development", "id": "GO:0031175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031175", "evidence": [ { "database": "UniProtKB", "id": "D3ZH78", "url": "https://www.uniprot.org/uniprotkb/D3ZH78" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "D3ZH78-1", "start_pos": "168", "end_pos": "168", "site_lbl": "Thr168", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 168, "start_aa": "Thr", "end_pos": 168, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr168", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "D3ZH78-1" }, { "uniprot_canonical_ac": "D3ZHG4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZHG4", "url": "https://www.uniprot.org/uniprotkb/D3ZHG4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 947, "chemical_mass": 105215.0, "gene_names": "Osbp2;Osbp2;RGD1309479", "protein_name": "Oxysterol-binding protein", "disease": [ { "disease_id": "DOID:4947", "name": "cholangiocarcinoma", "description": "A bile duct adenocarcinoma that has_material_basis_in bile duct epithelial cells.", "url": "https://disease-ontology.org/term/DOID:4947", "evidence": [ { "id": "4947", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4947" } ], "weight": 0.0 } ], "biological_process": [ { "name": "lipid transport", "id": "GO:0006869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006869", "evidence": [ { "database": "UniProtKB", "id": "D3ZHG4", "url": "https://www.uniprot.org/uniprotkb/D3ZHG4" } ], "pmid": "" }, { "name": "spermatid development", "id": "GO:0007286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007286", "evidence": [ { "database": "UniProtKB", "id": "D3ZHG4", "url": "https://www.uniprot.org/uniprotkb/D3ZHG4" } ], "pmid": "" } ], "cellular_component": [ { "name": "acrosomal vesicle", "id": "GO:0001669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001669", "evidence": [ { "database": "UniProtKB", "id": "D3ZHG4", "url": "https://www.uniprot.org/uniprotkb/D3ZHG4" } ], "pmid": "" }, { "name": "apical dendrite", "id": "GO:0097440", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097440", "evidence": [ { "database": "UniProtKB", "id": "D3ZHG4", "url": "https://www.uniprot.org/uniprotkb/D3ZHG4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "D3ZHG4", "url": "https://www.uniprot.org/uniprotkb/D3ZHG4" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "D3ZHG4", "url": "https://www.uniprot.org/uniprotkb/D3ZHG4" } ], "pmid": "" }, { "name": "perinuclear endoplasmic reticulum", "id": "GO:0097038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097038", "evidence": [ { "database": "UniProtKB", "id": "D3ZHG4", "url": "https://www.uniprot.org/uniprotkb/D3ZHG4" } ], "pmid": "" } ], "molecular_function": [ { "name": "cholesterol binding", "id": "GO:0015485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015485", "evidence": [ { "database": "UniProtKB", "id": "D3ZHG4", "url": "https://www.uniprot.org/uniprotkb/D3ZHG4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "D3ZHG4-1", "start_pos": "851", "end_pos": "851", "site_lbl": "Thr851", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 851, "start_aa": "Thr", "end_pos": 851, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr851", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "D3ZHG4-1" }, { "uniprot_canonical_ac": "D3ZHM7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZHM7", "url": "https://www.uniprot.org/uniprotkb/D3ZHM7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 761, "chemical_mass": 84785.0, "gene_names": "Dnttip2;Dnttip2;LOC100910753;RGD1309084", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "D3ZHM7", "url": "https://www.uniprot.org/uniprotkb/D3ZHM7" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "D3ZHM7", "url": "https://www.uniprot.org/uniprotkb/D3ZHM7" } ], "pmid": "" }, { "name": "small-subunit processome", "id": "GO:0032040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032040", "evidence": [ { "database": "UniProtKB", "id": "D3ZHM7", "url": "https://www.uniprot.org/uniprotkb/D3ZHM7" } ], "pmid": "" } ], "biological_process": [ { "name": "RNA processing", "id": "GO:0006396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006396", "evidence": [ { "database": "UniProtKB", "id": "D3ZHM7", "url": "https://www.uniprot.org/uniprotkb/D3ZHM7" } ], "pmid": "" }, { "name": "ribosomal small subunit biogenesis", "id": "GO:0042274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042274", "evidence": [ { "database": "UniProtKB", "id": "D3ZHM7", "url": "https://www.uniprot.org/uniprotkb/D3ZHM7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZHM7-1" }, { "uniprot_canonical_ac": "D3ZHQ8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZHQ8", "url": "https://www.uniprot.org/uniprotkb/D3ZHQ8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 541, "chemical_mass": 64792.0, "gene_names": "Zrsr2;RGD1559763;Zrsr2", "protein_name": "", "disease": [ { "disease_id": "DOID:0050908", "name": "myelodysplastic syndrome", "description": "A bone marrow cancer that is characterized by under production of white blood cells, red blood cells and platelets.", "url": "https://disease-ontology.org/term/DOID:0050908", "evidence": [ { "id": "0050908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050908" } ], "weight": 0.0 }, { "disease_id": "DOID:9119", "name": "acute myeloid leukemia", "description": "A myeloid leukemia that is characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal blood cells.", "url": "https://disease-ontology.org/term/DOID:9119", "evidence": [ { "id": "9119", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9119" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "D3ZHQ8", "url": "https://www.uniprot.org/uniprotkb/D3ZHQ8" } ], "pmid": "" }, { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "D3ZHQ8", "url": "https://www.uniprot.org/uniprotkb/D3ZHQ8" } ], "pmid": "" }, { "name": "U11/U12 snRNP", "id": "GO:0034693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034693", "evidence": [ { "database": "UniProtKB", "id": "D3ZHQ8", "url": "https://www.uniprot.org/uniprotkb/D3ZHQ8" } ], "pmid": "" }, { "name": "U12-type spliceosomal complex", "id": "GO:0005689", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005689", "evidence": [ { "database": "UniProtKB", "id": "D3ZHQ8", "url": "https://www.uniprot.org/uniprotkb/D3ZHQ8" } ], "pmid": "" }, { "name": "U2AF complex", "id": "GO:0089701", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0089701", "evidence": [ { "database": "UniProtKB", "id": "D3ZHQ8", "url": "https://www.uniprot.org/uniprotkb/D3ZHQ8" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "D3ZHQ8", "url": "https://www.uniprot.org/uniprotkb/D3ZHQ8" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "D3ZHQ8", "url": "https://www.uniprot.org/uniprotkb/D3ZHQ8" } ], "pmid": "" }, { "name": "pre-mRNA 3'-splice site binding", "id": "GO:0030628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030628", "evidence": [ { "database": "UniProtKB", "id": "D3ZHQ8", "url": "https://www.uniprot.org/uniprotkb/D3ZHQ8" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "D3ZHQ8", "url": "https://www.uniprot.org/uniprotkb/D3ZHQ8" } ], "pmid": "" }, { "name": "spliceosomal complex assembly", "id": "GO:0000245", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000245", "evidence": [ { "database": "UniProtKB", "id": "D3ZHQ8", "url": "https://www.uniprot.org/uniprotkb/D3ZHQ8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "D3ZHQ8-1", "start_pos": "7", "end_pos": "7", "site_lbl": "Thr7", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 7, "start_aa": "Thr", "end_pos": 7, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr7", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "D3ZHQ8-1" }, { "uniprot_canonical_ac": "D3ZHV6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZHV6", "url": "https://www.uniprot.org/uniprotkb/D3ZHV6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1101, "chemical_mass": 125623.0, "gene_names": "Tmc3;Tmc3", "protein_name": "Transmembrane channel-like protein", "disease": [], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "D3ZHV6", "url": "https://www.uniprot.org/uniprotkb/D3ZHV6" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "D3ZHV6", "url": "https://www.uniprot.org/uniprotkb/D3ZHV6" } ], "pmid": "" } ], "molecular_function": [ { "name": "mechanosensitive monoatomic ion channel activity", "id": "GO:0008381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008381", "evidence": [ { "database": "UniProtKB", "id": "D3ZHV6", "url": "https://www.uniprot.org/uniprotkb/D3ZHV6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZHV6-1" }, { "uniprot_canonical_ac": "D3ZHW0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZHW0", "url": "https://www.uniprot.org/uniprotkb/D3ZHW0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1366, "chemical_mass": 154119.0, "gene_names": "Dhx29;DHX29;Dhx29;LOC100362324", "protein_name": "ATP-dependent RNA helicase DHX29", "disease": [], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "D3ZHW0", "url": "https://www.uniprot.org/uniprotkb/D3ZHW0" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "D3ZHW0", "url": "https://www.uniprot.org/uniprotkb/D3ZHW0" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "D3ZHW0", "url": "https://www.uniprot.org/uniprotkb/D3ZHW0" } ], "pmid": "" }, { "name": "ribosomal small subunit binding", "id": "GO:0043024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043024", "evidence": [ { "database": "UniProtKB", "id": "D3ZHW0", "url": "https://www.uniprot.org/uniprotkb/D3ZHW0" } ], "pmid": "" }, { "name": "translation activator activity", "id": "GO:0008494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008494", "evidence": [ { "database": "UniProtKB", "id": "D3ZHW0", "url": "https://www.uniprot.org/uniprotkb/D3ZHW0" } ], "pmid": "" }, { "name": "translation initiation factor activity", "id": "GO:0003743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003743", "evidence": [ { "database": "UniProtKB", "id": "D3ZHW0", "url": "https://www.uniprot.org/uniprotkb/D3ZHW0" } ], "pmid": "" }, { "name": "helicase activity", "id": "GO:0004386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004386", "evidence": [ { "database": "UniProtKB", "id": "D3ZHW0", "url": "https://www.uniprot.org/uniprotkb/D3ZHW0" } ], "pmid": "" }, { "name": "ribonucleoside triphosphate phosphatase activity", "id": "GO:0017111", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017111", "evidence": [ { "database": "UniProtKB", "id": "D3ZHW0", "url": "https://www.uniprot.org/uniprotkb/D3ZHW0" } ], "pmid": "" }, { "name": "RNA helicase activity", "id": "GO:0003724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003724", "evidence": [ { "database": "UniProtKB", "id": "D3ZHW0", "url": "https://www.uniprot.org/uniprotkb/D3ZHW0" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "D3ZHW0", "url": "https://www.uniprot.org/uniprotkb/D3ZHW0" } ], "pmid": "" }, { "name": "hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides", "id": "GO:0016818", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016818", "evidence": [ { "database": "UniProtKB", "id": "D3ZHW0", "url": "https://www.uniprot.org/uniprotkb/D3ZHW0" } ], "pmid": "" } ], "biological_process": [ { "name": "formation of translation preinitiation complex", "id": "GO:0001731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001731", "evidence": [ { "database": "UniProtKB", "id": "D3ZHW0", "url": "https://www.uniprot.org/uniprotkb/D3ZHW0" } ], "pmid": "" }, { "name": "ribosome assembly", "id": "GO:0042255", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042255", "evidence": [ { "database": "UniProtKB", "id": "D3ZHW0", "url": "https://www.uniprot.org/uniprotkb/D3ZHW0" } ], "pmid": "" }, { "name": "positive regulation of translational initiation", "id": "GO:0045948", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045948", "evidence": [ { "database": "UniProtKB", "id": "D3ZHW0", "url": "https://www.uniprot.org/uniprotkb/D3ZHW0" } ], "pmid": "" } ], "cellular_component": [ { "name": "eukaryotic 43S preinitiation complex", "id": "GO:0016282", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016282", "evidence": [ { "database": "UniProtKB", "id": "D3ZHW0", "url": "https://www.uniprot.org/uniprotkb/D3ZHW0" } ], "pmid": "" }, { "name": "cytosolic small ribosomal subunit", "id": "GO:0022627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022627", "evidence": [ { "database": "UniProtKB", "id": "D3ZHW0", "url": "https://www.uniprot.org/uniprotkb/D3ZHW0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "D3ZHW0", "url": "https://www.uniprot.org/uniprotkb/D3ZHW0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZHW0-1" }, { "uniprot_canonical_ac": "D3ZI87-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZI87", "url": "https://www.uniprot.org/uniprotkb/D3ZI87" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 559, "chemical_mass": 63326.0, "gene_names": "Prdm14;LOC100365184;Prdm14", "protein_name": "PR domain zinc finger protein 14", "disease": [ { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 } ], "biological_process": [ { "name": "cell fate specification", "id": "GO:0001708", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001708", "evidence": [ { "database": "UniProtKB", "id": "D3ZI87", "url": "https://www.uniprot.org/uniprotkb/D3ZI87" } ], "pmid": "" }, { "name": "positive regulation of stem cell population maintenance", "id": "GO:1902459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902459", "evidence": [ { "database": "UniProtKB", "id": "D3ZI87", "url": "https://www.uniprot.org/uniprotkb/D3ZI87" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "D3ZI87", "url": "https://www.uniprot.org/uniprotkb/D3ZI87" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "D3ZI87", "url": "https://www.uniprot.org/uniprotkb/D3ZI87" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "D3ZI87", "url": "https://www.uniprot.org/uniprotkb/D3ZI87" } ], "pmid": "" }, { "name": "fertilization", "id": "GO:0009566", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009566", "evidence": [ { "database": "UniProtKB", "id": "D3ZI87", "url": "https://www.uniprot.org/uniprotkb/D3ZI87" } ], "pmid": "" }, { "name": "cell morphogenesis", "id": "GO:0000902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000902", "evidence": [ { "database": "UniProtKB", "id": "D3ZI87", "url": "https://www.uniprot.org/uniprotkb/D3ZI87" } ], "pmid": "" }, { "name": "homeostasis of number of cells within a tissue", "id": "GO:0048873", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048873", "evidence": [ { "database": "UniProtKB", "id": "D3ZI87", "url": "https://www.uniprot.org/uniprotkb/D3ZI87" } ], "pmid": "" }, { "name": "stem cell population maintenance", "id": "GO:0019827", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019827", "evidence": [ { "database": "UniProtKB", "id": "D3ZI87", "url": "https://www.uniprot.org/uniprotkb/D3ZI87" } ], "pmid": "" }, { "name": "germ cell development", "id": "GO:0007281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007281", "evidence": [ { "database": "UniProtKB", "id": "D3ZI87", "url": "https://www.uniprot.org/uniprotkb/D3ZI87" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "D3ZI87", "url": "https://www.uniprot.org/uniprotkb/D3ZI87" } ], "pmid": "" }, { "name": "negative regulation of gene expression, epigenetic", "id": "GO:0045814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045814", "evidence": [ { "database": "UniProtKB", "id": "D3ZI87", "url": "https://www.uniprot.org/uniprotkb/D3ZI87" } ], "pmid": "" }, { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "D3ZI87", "url": "https://www.uniprot.org/uniprotkb/D3ZI87" } ], "pmid": "" }, { "name": "epigenetic regulation of gene expression", "id": "GO:0040029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040029", "evidence": [ { "database": "UniProtKB", "id": "D3ZI87", "url": "https://www.uniprot.org/uniprotkb/D3ZI87" } ], "pmid": "" }, { "name": "embryo implantation", "id": "GO:0007566", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007566", "evidence": [ { "database": "UniProtKB", "id": "D3ZI87", "url": "https://www.uniprot.org/uniprotkb/D3ZI87" } ], "pmid": "" }, { "name": "negative regulation of fibroblast growth factor receptor signaling pathway", "id": "GO:0040037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040037", "evidence": [ { "database": "UniProtKB", "id": "D3ZI87", "url": "https://www.uniprot.org/uniprotkb/D3ZI87" } ], "pmid": "" }, { "name": "inner cell mass cell fate commitment", "id": "GO:0001827", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001827", "evidence": [ { "database": "UniProtKB", "id": "D3ZI87", "url": "https://www.uniprot.org/uniprotkb/D3ZI87" } ], "pmid": "" }, { "name": "positive regulation of flagellated sperm motility", "id": "GO:1902093", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902093", "evidence": [ { "database": "UniProtKB", "id": "D3ZI87", "url": "https://www.uniprot.org/uniprotkb/D3ZI87" } ], "pmid": "" }, { "name": "germ-line stem cell population maintenance", "id": "GO:0030718", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030718", "evidence": [ { "database": "UniProtKB", "id": "D3ZI87", "url": "https://www.uniprot.org/uniprotkb/D3ZI87" } ], "pmid": "" }, { "name": "inactivation of paternal X chromosome by genomic imprinting", "id": "GO:0060818", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060818", "evidence": [ { "database": "UniProtKB", "id": "D3ZI87", "url": "https://www.uniprot.org/uniprotkb/D3ZI87" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "D3ZI87", "url": "https://www.uniprot.org/uniprotkb/D3ZI87" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "D3ZI87", "url": "https://www.uniprot.org/uniprotkb/D3ZI87" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "D3ZI87", "url": "https://www.uniprot.org/uniprotkb/D3ZI87" } ], "pmid": "" }, { "name": "methyltransferase activity", "id": "GO:0008168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008168", "evidence": [ { "database": "UniProtKB", "id": "D3ZI87", "url": "https://www.uniprot.org/uniprotkb/D3ZI87" } ], "pmid": "" }, { "name": "chromatin DNA binding", "id": "GO:0031490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031490", "evidence": [ { "database": "UniProtKB", "id": "D3ZI87", "url": "https://www.uniprot.org/uniprotkb/D3ZI87" } ], "pmid": "" }, { "name": "histone methyltransferase binding", "id": "GO:1990226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990226", "evidence": [ { "database": "UniProtKB", "id": "D3ZI87", "url": "https://www.uniprot.org/uniprotkb/D3ZI87" } ], "pmid": "" }, { "name": "methyltransferase regulator activity", "id": "GO:0141107", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141107", "evidence": [ { "database": "UniProtKB", "id": "D3ZI87", "url": "https://www.uniprot.org/uniprotkb/D3ZI87" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D3ZI87", "url": "https://www.uniprot.org/uniprotkb/D3ZI87" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "D3ZI87", "url": "https://www.uniprot.org/uniprotkb/D3ZI87" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZI87-1" }, { "uniprot_canonical_ac": "D3ZIC2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZIC2", "url": "https://www.uniprot.org/uniprotkb/D3ZIC2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 676, "chemical_mass": 74692.0, "gene_names": "Uroc1;Uroc1", "protein_name": "Urocanate hydratase", "disease": [ { "disease_id": "DOID:0112180", "name": "urocanase deficiency", "description": "A histidine metabolism disease characterized by urocanic aciduria and other variable manifestations including intellectual disability and intermittent ataxia that has_material_basis_in mutation homozygous or compound heterozygous in the UROC1 gene on chromosome 3q21.3.", "url": "https://disease-ontology.org/term/DOID:0112180", "evidence": [ { "id": "0112180", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112180" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "urocanate hydratase activity", "id": "GO:0016153", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016153", "evidence": [ { "database": "UniProtKB", "id": "D3ZIC2", "url": "https://www.uniprot.org/uniprotkb/D3ZIC2" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "D3ZIC2", "url": "https://www.uniprot.org/uniprotkb/D3ZIC2" } ], "pmid": "" } ], "biological_process": [ { "name": "L-histidine catabolic process to glutamate and formamide", "id": "GO:0019556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019556", "evidence": [ { "database": "UniProtKB", "id": "D3ZIC2", "url": "https://www.uniprot.org/uniprotkb/D3ZIC2" } ], "pmid": "" }, { "name": "L-histidine catabolic process to glutamate and formate", "id": "GO:0019557", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019557", "evidence": [ { "database": "UniProtKB", "id": "D3ZIC2", "url": "https://www.uniprot.org/uniprotkb/D3ZIC2" } ], "pmid": "" }, { "name": "L-histidine catabolic process", "id": "GO:0006548", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006548", "evidence": [ { "database": "UniProtKB", "id": "D3ZIC2", "url": "https://www.uniprot.org/uniprotkb/D3ZIC2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZIC2-1" }, { "uniprot_canonical_ac": "D3ZII7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZII7", "url": "https://www.uniprot.org/uniprotkb/D3ZII7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 314, "chemical_mass": 32874.0, "gene_names": "Yaf2", "protein_name": "", "disease": [], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "D3ZII7", "url": "https://www.uniprot.org/uniprotkb/D3ZII7" } ], "pmid": "" }, { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "D3ZII7", "url": "https://www.uniprot.org/uniprotkb/D3ZII7" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "D3ZII7", "url": "https://www.uniprot.org/uniprotkb/D3ZII7" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "D3ZII7", "url": "https://www.uniprot.org/uniprotkb/D3ZII7" } ], "pmid": "" }, { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "D3ZII7", "url": "https://www.uniprot.org/uniprotkb/D3ZII7" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D3ZII7", "url": "https://www.uniprot.org/uniprotkb/D3ZII7" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "D3ZII7", "url": "https://www.uniprot.org/uniprotkb/D3ZII7" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "D3ZII7", "url": "https://www.uniprot.org/uniprotkb/D3ZII7" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "D3ZII7", "url": "https://www.uniprot.org/uniprotkb/D3ZII7" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "D3ZII7", "url": "https://www.uniprot.org/uniprotkb/D3ZII7" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "D3ZII7", "url": "https://www.uniprot.org/uniprotkb/D3ZII7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "D3ZII7-1", "start_pos": "81", "end_pos": "81", "site_lbl": "Thr81", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 81, "start_aa": "Thr", "end_pos": 81, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr81", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "D3ZII7-1" }, { "uniprot_canonical_ac": "D3ZIP8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZIP8", "url": "https://www.uniprot.org/uniprotkb/D3ZIP8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 500, "chemical_mass": 54719.0, "gene_names": "Endod1;AABR07069219.1;Endod1;RGD1310444", "protein_name": "", "disease": [], "molecular_function": [ { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "D3ZIP8", "url": "https://www.uniprot.org/uniprotkb/D3ZIP8" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "D3ZIP8", "url": "https://www.uniprot.org/uniprotkb/D3ZIP8" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "D3ZIP8", "url": "https://www.uniprot.org/uniprotkb/D3ZIP8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZIP8-1" }, { "uniprot_canonical_ac": "D3ZIX4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZIX4", "url": "https://www.uniprot.org/uniprotkb/D3ZIX4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 252, "chemical_mass": 27023.0, "gene_names": "H1f10;H1fx", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D3ZIX4", "url": "https://www.uniprot.org/uniprotkb/D3ZIX4" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "D3ZIX4", "url": "https://www.uniprot.org/uniprotkb/D3ZIX4" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "D3ZIX4", "url": "https://www.uniprot.org/uniprotkb/D3ZIX4" } ], "pmid": "" }, { "name": "nucleosome", "id": "GO:0000786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000786", "evidence": [ { "database": "UniProtKB", "id": "D3ZIX4", "url": "https://www.uniprot.org/uniprotkb/D3ZIX4" } ], "pmid": "" } ], "molecular_function": [ { "name": "double-stranded DNA binding", "id": "GO:0003690", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003690", "evidence": [ { "database": "UniProtKB", "id": "D3ZIX4", "url": "https://www.uniprot.org/uniprotkb/D3ZIX4" } ], "pmid": "" }, { "name": "nucleosomal DNA binding", "id": "GO:0031492", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031492", "evidence": [ { "database": "UniProtKB", "id": "D3ZIX4", "url": "https://www.uniprot.org/uniprotkb/D3ZIX4" } ], "pmid": "" }, { "name": "structural constituent of chromatin", "id": "GO:0030527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030527", "evidence": [ { "database": "UniProtKB", "id": "D3ZIX4", "url": "https://www.uniprot.org/uniprotkb/D3ZIX4" } ], "pmid": "" } ], "biological_process": [ { "name": "nucleosome assembly", "id": "GO:0006334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006334", "evidence": [ { "database": "UniProtKB", "id": "D3ZIX4", "url": "https://www.uniprot.org/uniprotkb/D3ZIX4" } ], "pmid": "" }, { "name": "chromosome condensation", "id": "GO:0030261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030261", "evidence": [ { "database": "UniProtKB", "id": "D3ZIX4", "url": "https://www.uniprot.org/uniprotkb/D3ZIX4" } ], "pmid": "" }, { "name": "negative regulation of DNA recombination", "id": "GO:0045910", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045910", "evidence": [ { "database": "UniProtKB", "id": "D3ZIX4", "url": "https://www.uniprot.org/uniprotkb/D3ZIX4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZIX4-1" }, { "uniprot_canonical_ac": "D3ZJ17-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZJ17", "url": "https://www.uniprot.org/uniprotkb/D3ZJ17" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 715, "chemical_mass": 81762.0, "gene_names": "Ttll6;Ttll6-ps1", "protein_name": "", "disease": [], "biological_process": [ { "name": "microtubule severing", "id": "GO:0051013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051013", "evidence": [ { "database": "UniProtKB", "id": "D3ZJ17", "url": "https://www.uniprot.org/uniprotkb/D3ZJ17" } ], "pmid": "" }, { "name": "protein polyglutamylation", "id": "GO:0018095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018095", "evidence": [ { "database": "UniProtKB", "id": "D3ZJ17", "url": "https://www.uniprot.org/uniprotkb/D3ZJ17" } ], "pmid": "" }, { "name": "regulation of cilium beat frequency involved in ciliary motility", "id": "GO:0060296", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060296", "evidence": [ { "database": "UniProtKB", "id": "D3ZJ17", "url": "https://www.uniprot.org/uniprotkb/D3ZJ17" } ], "pmid": "" }, { "name": "microtubule bundle formation", "id": "GO:0001578", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001578", "evidence": [ { "database": "UniProtKB", "id": "D3ZJ17", "url": "https://www.uniprot.org/uniprotkb/D3ZJ17" } ], "pmid": "" }, { "name": "positive regulation of cilium movement", "id": "GO:0003353", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003353", "evidence": [ { "database": "UniProtKB", "id": "D3ZJ17", "url": "https://www.uniprot.org/uniprotkb/D3ZJ17" } ], "pmid": "" } ], "molecular_function": [ { "name": "tubulin-glutamic acid ligase activity", "id": "GO:0070740", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070740", "evidence": [ { "database": "UniProtKB", "id": "D3ZJ17", "url": "https://www.uniprot.org/uniprotkb/D3ZJ17" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "D3ZJ17", "url": "https://www.uniprot.org/uniprotkb/D3ZJ17" } ], "pmid": "" }, { "name": "tubulin binding", "id": "GO:0015631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015631", "evidence": [ { "database": "UniProtKB", "id": "D3ZJ17", "url": "https://www.uniprot.org/uniprotkb/D3ZJ17" } ], "pmid": "" }, { "name": "protein-glutamic acid ligase activity", "id": "GO:0070739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070739", "evidence": [ { "database": "UniProtKB", "id": "D3ZJ17", "url": "https://www.uniprot.org/uniprotkb/D3ZJ17" } ], "pmid": "" } ], "cellular_component": [ { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "D3ZJ17", "url": "https://www.uniprot.org/uniprotkb/D3ZJ17" } ], "pmid": "" }, { "name": "microtubule cytoskeleton", "id": "GO:0015630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015630", "evidence": [ { "database": "UniProtKB", "id": "D3ZJ17", "url": "https://www.uniprot.org/uniprotkb/D3ZJ17" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "D3ZJ17", "url": "https://www.uniprot.org/uniprotkb/D3ZJ17" } ], "pmid": "" }, { "name": "9+0 non-motile cilium", "id": "GO:0097731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097731", "evidence": [ { "database": "UniProtKB", "id": "D3ZJ17", "url": "https://www.uniprot.org/uniprotkb/D3ZJ17" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "D3ZJ17-1", "start_pos": "530", "end_pos": "530", "site_lbl": "Thr530", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 530, "start_aa": "Thr", "end_pos": 530, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr530", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "D3ZJ17-1" }, { "uniprot_canonical_ac": "D3ZJ49-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZJ49", "url": "https://www.uniprot.org/uniprotkb/D3ZJ49" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 685, "chemical_mass": 78309.0, "gene_names": "Usp49;RGD1310513;Usp49", "protein_name": "Ubiquitin carboxyl-terminal hydrolase", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D3ZJ49", "url": "https://www.uniprot.org/uniprotkb/D3ZJ49" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "D3ZJ49", "url": "https://www.uniprot.org/uniprotkb/D3ZJ49" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "D3ZJ49", "url": "https://www.uniprot.org/uniprotkb/D3ZJ49" } ], "pmid": "" }, { "name": "protein deubiquitination", "id": "GO:0016579", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016579", "evidence": [ { "database": "UniProtKB", "id": "D3ZJ49", "url": "https://www.uniprot.org/uniprotkb/D3ZJ49" } ], "pmid": "" }, { "name": "negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction", "id": "GO:0051898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051898", "evidence": [ { "database": "UniProtKB", "id": "D3ZJ49", "url": "https://www.uniprot.org/uniprotkb/D3ZJ49" } ], "pmid": "" }, { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "D3ZJ49", "url": "https://www.uniprot.org/uniprotkb/D3ZJ49" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "D3ZJ49", "url": "https://www.uniprot.org/uniprotkb/D3ZJ49" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "D3ZJ49", "url": "https://www.uniprot.org/uniprotkb/D3ZJ49" } ], "pmid": "" }, { "name": "cysteine-type endopeptidase activity", "id": "GO:0004197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004197", "evidence": [ { "database": "UniProtKB", "id": "D3ZJ49", "url": "https://www.uniprot.org/uniprotkb/D3ZJ49" } ], "pmid": "" }, { "name": "cysteine-type deubiquitinase activity", "id": "GO:0004843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004843", "evidence": [ { "database": "UniProtKB", "id": "D3ZJ49", "url": "https://www.uniprot.org/uniprotkb/D3ZJ49" } ], "pmid": "" }, { "name": "histone H2B deubiquitinase activity", "id": "GO:0140936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140936", "evidence": [ { "database": "UniProtKB", "id": "D3ZJ49", "url": "https://www.uniprot.org/uniprotkb/D3ZJ49" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZJ49-1" }, { "uniprot_canonical_ac": "D3ZJ65-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZJ65", "url": "https://www.uniprot.org/uniprotkb/D3ZJ65" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 409, "chemical_mass": 45998.0, "gene_names": "Dipk1c;Dipk1c;Fam69c;RGD1559694", "protein_name": "", "disease": [], "molecular_function": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "D3ZJ65", "url": "https://www.uniprot.org/uniprotkb/D3ZJ65" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "D3ZJ65", "url": "https://www.uniprot.org/uniprotkb/D3ZJ65" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZJ65-1" }, { "uniprot_canonical_ac": "D3ZJ69-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZJ69", "url": "https://www.uniprot.org/uniprotkb/D3ZJ69" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 442, "chemical_mass": 46341.0, "gene_names": "Tfap2e;RGD1563297;Tcfap2e;Tfap2e", "protein_name": "", "disease": [ { "disease_id": "DOID:535", "name": "sleep disorder", "description": "A disease of mental health that involves disruption of sleep patterns.", "url": "https://disease-ontology.org/term/DOID:535", "evidence": [ { "id": "535", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:535" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "D3ZJ69", "url": "https://www.uniprot.org/uniprotkb/D3ZJ69" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "D3ZJ69", "url": "https://www.uniprot.org/uniprotkb/D3ZJ69" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "D3ZJ69", "url": "https://www.uniprot.org/uniprotkb/D3ZJ69" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "D3ZJ69", "url": "https://www.uniprot.org/uniprotkb/D3ZJ69" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "D3ZJ69", "url": "https://www.uniprot.org/uniprotkb/D3ZJ69" } ], "pmid": "" }, { "name": "sequence-specific double-stranded DNA binding", "id": "GO:1990837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990837", "evidence": [ { "database": "UniProtKB", "id": "D3ZJ69", "url": "https://www.uniprot.org/uniprotkb/D3ZJ69" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D3ZJ69", "url": "https://www.uniprot.org/uniprotkb/D3ZJ69" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "D3ZJ69", "url": "https://www.uniprot.org/uniprotkb/D3ZJ69" } ], "pmid": "" }, { "name": "regulation of cell population proliferation", "id": "GO:0042127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042127", "evidence": [ { "database": "UniProtKB", "id": "D3ZJ69", "url": "https://www.uniprot.org/uniprotkb/D3ZJ69" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "D3ZJ69", "url": "https://www.uniprot.org/uniprotkb/D3ZJ69" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZJ69-1" }, { "uniprot_canonical_ac": "D3ZJE0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZJE0", "url": "https://www.uniprot.org/uniprotkb/D3ZJE0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 650, "chemical_mass": 73420.0, "gene_names": "Edem1;Edem1;RGD1563633", "protein_name": "alpha-1,2-Mannosidase", "disease": [ { "disease_id": "DOID:1485", "name": "cystic fibrosis", "description": "A syndrome that is characterized by the buildup of thick, sticky mucus that can damage many organs.", "url": "https://disease-ontology.org/term/DOID:1485", "evidence": [ { "id": "1485", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1485" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "D3ZJE0", "url": "https://www.uniprot.org/uniprotkb/D3ZJE0" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "D3ZJE0", "url": "https://www.uniprot.org/uniprotkb/D3ZJE0" } ], "pmid": "" }, { "name": "endoplasmic reticulum quality control compartment", "id": "GO:0044322", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044322", "evidence": [ { "database": "UniProtKB", "id": "D3ZJE0", "url": "https://www.uniprot.org/uniprotkb/D3ZJE0" } ], "pmid": "" } ], "biological_process": [ { "name": "carbohydrate metabolic process", "id": "GO:0005975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005975", "evidence": [ { "database": "UniProtKB", "id": "D3ZJE0", "url": "https://www.uniprot.org/uniprotkb/D3ZJE0" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "D3ZJE0", "url": "https://www.uniprot.org/uniprotkb/D3ZJE0" } ], "pmid": "" }, { "name": "ERAD pathway", "id": "GO:0036503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036503", "evidence": [ { "database": "UniProtKB", "id": "D3ZJE0", "url": "https://www.uniprot.org/uniprotkb/D3ZJE0" } ], "pmid": "" }, { "name": "endoplasmic reticulum mannose trimming", "id": "GO:1904380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904380", "evidence": [ { "database": "UniProtKB", "id": "D3ZJE0", "url": "https://www.uniprot.org/uniprotkb/D3ZJE0" } ], "pmid": "" }, { "name": "positive regulation of retrograde protein transport, ER to cytosol", "id": "GO:1904154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904154", "evidence": [ { "database": "UniProtKB", "id": "D3ZJE0", "url": "https://www.uniprot.org/uniprotkb/D3ZJE0" } ], "pmid": "" }, { "name": "protein targeting to ER", "id": "GO:0045047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045047", "evidence": [ { "database": "UniProtKB", "id": "D3ZJE0", "url": "https://www.uniprot.org/uniprotkb/D3ZJE0" } ], "pmid": "" }, { "name": "response to unfolded protein", "id": "GO:0006986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006986", "evidence": [ { "database": "UniProtKB", "id": "D3ZJE0", "url": "https://www.uniprot.org/uniprotkb/D3ZJE0" } ], "pmid": "" } ], "molecular_function": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "D3ZJE0", "url": "https://www.uniprot.org/uniprotkb/D3ZJE0" } ], "pmid": "" }, { "name": "misfolded protein binding", "id": "GO:0051787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051787", "evidence": [ { "database": "UniProtKB", "id": "D3ZJE0", "url": "https://www.uniprot.org/uniprotkb/D3ZJE0" } ], "pmid": "" }, { "name": "mannosyl-oligosaccharide 1,2-alpha-mannosidase activity", "id": "GO:0004571", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004571", "evidence": [ { "database": "UniProtKB", "id": "D3ZJE0", "url": "https://www.uniprot.org/uniprotkb/D3ZJE0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZJE0-1" }, { "uniprot_canonical_ac": "D3ZJM7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZJM7", "url": "https://www.uniprot.org/uniprotkb/D3ZJM7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 836, "chemical_mass": 92371.0, "gene_names": "Mcph1", "protein_name": "Microcephalin", "disease": [ { "disease_id": "DOID:0050866", "name": "oral squamous cell carcinoma", "description": "An oral cavity cancer that has_material_basis_in squamous cells.", "url": "https://disease-ontology.org/term/DOID:0050866", "evidence": [ { "id": "0050866", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050866" } ], "weight": 0.0 }, { "disease_id": "DOID:0070285", "name": "primary autosomal recessive microcephaly 1", "description": "A primary autosomal recessive microcephaly that has_material_basis_in homozygous or compound heterozygous mutation in the MCPH1 gene on chromosome 8p23.", "url": "https://disease-ontology.org/term/DOID:0070285", "evidence": [ { "id": "0070285", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070285" } ], "weight": 0.0 }, { "disease_id": "DOID:0070296", "name": "autosomal recessive primary microcephaly", "description": "A primary microcephaly characterized by microcephaly present at birth, where the brain is small but has normal architecture, and nonprogressive mental retardation that has_material_basis_in an autosomal recessive mutation.", "url": "https://disease-ontology.org/term/DOID:0070296", "evidence": [ { "id": "0070296", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070296" } ], "weight": 0.0 }, { "disease_id": "DOID:10907", "name": "microcephaly", "description": "A congenital nervous system abnormality that is characterized by a significantly smaller than normal head in infants.", "url": "https://disease-ontology.org/term/DOID:10907", "evidence": [ { "id": "10907", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10907" } ], "weight": 0.0 }, { "disease_id": "DOID:1380", "name": "endometrial cancer", "description": "A uterine cancer that is located_in tissues lining the uterus.", "url": "https://disease-ontology.org/term/DOID:1380", "evidence": [ { "id": "1380", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1380" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:4451", "name": "renal carcinoma", "description": "A kidney cancer that derives_from the lining of the proximal convoluted tubule (the very small tubes in the kidney that filter the blood and remove waste products).", "url": "https://disease-ontology.org/term/DOID:4451", "evidence": [ { "id": "4451", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4451" } ], "weight": 0.0 } ], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "D3ZJM7", "url": "https://www.uniprot.org/uniprotkb/D3ZJM7" } ], "pmid": "" }, { "name": "mitotic cell cycle", "id": "GO:0000278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000278", "evidence": [ { "database": "UniProtKB", "id": "D3ZJM7", "url": "https://www.uniprot.org/uniprotkb/D3ZJM7" } ], "pmid": "" }, { "name": "cerebral cortex development", "id": "GO:0021987", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021987", "evidence": [ { "database": "UniProtKB", "id": "D3ZJM7", "url": "https://www.uniprot.org/uniprotkb/D3ZJM7" } ], "pmid": "" }, { "name": "regulation of inflammatory response", "id": "GO:0050727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050727", "evidence": [ { "database": "UniProtKB", "id": "D3ZJM7", "url": "https://www.uniprot.org/uniprotkb/D3ZJM7" } ], "pmid": "" }, { "name": "bone development", "id": "GO:0060348", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060348", "evidence": [ { "database": "UniProtKB", "id": "D3ZJM7", "url": "https://www.uniprot.org/uniprotkb/D3ZJM7" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "D3ZJM7", "url": "https://www.uniprot.org/uniprotkb/D3ZJM7" } ], "pmid": "" }, { "name": "establishment of mitotic spindle orientation", "id": "GO:0000132", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000132", "evidence": [ { "database": "UniProtKB", "id": "D3ZJM7", "url": "https://www.uniprot.org/uniprotkb/D3ZJM7" } ], "pmid": "" }, { "name": "neuronal stem cell population maintenance", "id": "GO:0097150", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097150", "evidence": [ { "database": "UniProtKB", "id": "D3ZJM7", "url": "https://www.uniprot.org/uniprotkb/D3ZJM7" } ], "pmid": "" }, { "name": "regulation of centrosome cycle", "id": "GO:0046605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046605", "evidence": [ { "database": "UniProtKB", "id": "D3ZJM7", "url": "https://www.uniprot.org/uniprotkb/D3ZJM7" } ], "pmid": "" }, { "name": "protein localization to centrosome", "id": "GO:0071539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071539", "evidence": [ { "database": "UniProtKB", "id": "D3ZJM7", "url": "https://www.uniprot.org/uniprotkb/D3ZJM7" } ], "pmid": "" }, { "name": "regulation of chromosome condensation", "id": "GO:0060623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060623", "evidence": [ { "database": "UniProtKB", "id": "D3ZJM7", "url": "https://www.uniprot.org/uniprotkb/D3ZJM7" } ], "pmid": "" }, { "name": "regulation of kinase activity", "id": "GO:0043549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043549", "evidence": [ { "database": "UniProtKB", "id": "D3ZJM7", "url": "https://www.uniprot.org/uniprotkb/D3ZJM7" } ], "pmid": "" } ], "cellular_component": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "D3ZJM7", "url": "https://www.uniprot.org/uniprotkb/D3ZJM7" } ], "pmid": "" } ], "molecular_function": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "D3ZJM7", "url": "https://www.uniprot.org/uniprotkb/D3ZJM7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZJM7-1" }, { "uniprot_canonical_ac": "D3ZJU0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZJU0", "url": "https://www.uniprot.org/uniprotkb/D3ZJU0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1826, "chemical_mass": 195057.0, "gene_names": "Arid2;Arid2", "protein_name": "AT-rich interactive domain-containing protein 2", "disease": [ { "disease_id": "DOID:0050866", "name": "oral squamous cell carcinoma", "description": "An oral cavity cancer that has_material_basis_in squamous cells.", "url": "https://disease-ontology.org/term/DOID:0050866", "evidence": [ { "id": "0050866", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050866" } ], "weight": 0.0 }, { "disease_id": "DOID:0080297", "name": "Coffin-Siris syndrome 6", "description": "A Coffin-Siris syndrome that is characterized by short stature, sparse hair, mild to severe intellectual disability, coarse facial features, and variable behavioral anomalies and that has_material_basis_in heterozygous mutation in the ARID2 gene on chromosome 12q12.", "url": "https://disease-ontology.org/term/DOID:0080297", "evidence": [ { "id": "0080297", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080297" } ], "weight": 0.0 }, { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 } ], "biological_process": [ { "name": "circulatory system development", "id": "GO:0072359", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072359", "evidence": [ { "database": "UniProtKB", "id": "D3ZJU0", "url": "https://www.uniprot.org/uniprotkb/D3ZJU0" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "D3ZJU0", "url": "https://www.uniprot.org/uniprotkb/D3ZJU0" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "D3ZJU0", "url": "https://www.uniprot.org/uniprotkb/D3ZJU0" } ], "pmid": "" }, { "name": "negative regulation of cell population proliferation", "id": "GO:0008285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008285", "evidence": [ { "database": "UniProtKB", "id": "D3ZJU0", "url": "https://www.uniprot.org/uniprotkb/D3ZJU0" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "D3ZJU0", "url": "https://www.uniprot.org/uniprotkb/D3ZJU0" } ], "pmid": "" }, { "name": "negative regulation of cell migration", "id": "GO:0030336", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030336", "evidence": [ { "database": "UniProtKB", "id": "D3ZJU0", "url": "https://www.uniprot.org/uniprotkb/D3ZJU0" } ], "pmid": "" }, { "name": "heart morphogenesis", "id": "GO:0003007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003007", "evidence": [ { "database": "UniProtKB", "id": "D3ZJU0", "url": "https://www.uniprot.org/uniprotkb/D3ZJU0" } ], "pmid": "" }, { "name": "homeostatic process", "id": "GO:0042592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042592", "evidence": [ { "database": "UniProtKB", "id": "D3ZJU0", "url": "https://www.uniprot.org/uniprotkb/D3ZJU0" } ], "pmid": "" }, { "name": "nucleosome disassembly", "id": "GO:0006337", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006337", "evidence": [ { "database": "UniProtKB", "id": "D3ZJU0", "url": "https://www.uniprot.org/uniprotkb/D3ZJU0" } ], "pmid": "" }, { "name": "embryonic organ development", "id": "GO:0048568", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048568", "evidence": [ { "database": "UniProtKB", "id": "D3ZJU0", "url": "https://www.uniprot.org/uniprotkb/D3ZJU0" } ], "pmid": "" }, { "name": "cardiac muscle cell proliferation", "id": "GO:0060038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060038", "evidence": [ { "database": "UniProtKB", "id": "D3ZJU0", "url": "https://www.uniprot.org/uniprotkb/D3ZJU0" } ], "pmid": "" }, { "name": "coronary artery morphogenesis", "id": "GO:0060982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060982", "evidence": [ { "database": "UniProtKB", "id": "D3ZJU0", "url": "https://www.uniprot.org/uniprotkb/D3ZJU0" } ], "pmid": "" }, { "name": "positive regulation of double-strand break repair via homologous recombination", "id": "GO:1905168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905168", "evidence": [ { "database": "UniProtKB", "id": "D3ZJU0", "url": "https://www.uniprot.org/uniprotkb/D3ZJU0" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "D3ZJU0", "url": "https://www.uniprot.org/uniprotkb/D3ZJU0" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "D3ZJU0", "url": "https://www.uniprot.org/uniprotkb/D3ZJU0" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "D3ZJU0", "url": "https://www.uniprot.org/uniprotkb/D3ZJU0" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "D3ZJU0", "url": "https://www.uniprot.org/uniprotkb/D3ZJU0" } ], "pmid": "" }, { "name": "SWI/SNF complex", "id": "GO:0016514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016514", "evidence": [ { "database": "UniProtKB", "id": "D3ZJU0", "url": "https://www.uniprot.org/uniprotkb/D3ZJU0" } ], "pmid": "" }, { "name": "brahma complex", "id": "GO:0035060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035060", "evidence": [ { "database": "UniProtKB", "id": "D3ZJU0", "url": "https://www.uniprot.org/uniprotkb/D3ZJU0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "D3ZJU0-1", "start_pos": "1001", "end_pos": "1001", "site_lbl": "Thr1001", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1001, "start_aa": "Thr", "end_pos": 1001, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1001", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "D3ZJU0-1", "start_pos": "633", "end_pos": "633", "site_lbl": "Thr633", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 633, "start_aa": "Thr", "end_pos": 633, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr633", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "D3ZJU0-1" }, { "uniprot_canonical_ac": "D3ZKC9-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZKC9", "url": "https://www.uniprot.org/uniprotkb/D3ZKC9" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1931, "chemical_mass": 215857.0, "gene_names": "Virma;RGD1559904", "protein_name": "", "disease": [], "cellular_component": [ { "name": "RNA N6-methyladenosine methyltransferase complex", "id": "GO:0036396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036396", "evidence": [ { "database": "UniProtKB", "id": "D3ZKC9", "url": "https://www.uniprot.org/uniprotkb/D3ZKC9" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D3ZKC9", "url": "https://www.uniprot.org/uniprotkb/D3ZKC9" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "D3ZKC9", "url": "https://www.uniprot.org/uniprotkb/D3ZKC9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "D3ZKC9", "url": "https://www.uniprot.org/uniprotkb/D3ZKC9" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "D3ZKC9", "url": "https://www.uniprot.org/uniprotkb/D3ZKC9" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "D3ZKC9", "url": "https://www.uniprot.org/uniprotkb/D3ZKC9" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "D3ZKC9", "url": "https://www.uniprot.org/uniprotkb/D3ZKC9" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "D3ZKC9", "url": "https://www.uniprot.org/uniprotkb/D3ZKC9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZKC9-1" }, { "uniprot_canonical_ac": "D3ZKE0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZKE0", "url": "https://www.uniprot.org/uniprotkb/D3ZKE0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1228, "chemical_mass": 140017.0, "gene_names": "Gnptab;Gnptab;RGD1564821", "protein_name": "N-acetylglucosamine-1-phosphotransferase subunits alpha/beta", "disease": [ { "disease_id": "DOID:0080070", "name": "mucolipidosis II alpha/beta", "description": "A mucolipidosis that is characterized by short stature, skeletal abnormalities, cardiomegaly, and developmental delay, caused by a defect in proper lysosomal enzyme phosphorylation and localization, which results in accumulation of lysosomal substrates, and that has_material_basis_in homozygous or compound heterozygous mutation in the GNPTAB gene.", "url": "https://disease-ontology.org/term/DOID:0080070", "evidence": [ { "id": "0080070", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080070" } ], "weight": 0.0 }, { "disease_id": "DOID:0080071", "name": "mucolipidosis III alpha/beta", "description": "A mucolipidosis that has_material_basis_in mutation in the gene encoding the alpha/beta-subunits precursor gene of GLcNAc-phosphotransferase.", "url": "https://disease-ontology.org/term/DOID:0080071", "evidence": [ { "id": "0080071", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080071" } ], "weight": 0.0 }, { "disease_id": "DOID:0080488", "name": "mucolipidosis", "description": "A lipid storage disease that is characterized by increased storage of carbohydrates and lipids.", "url": "https://disease-ontology.org/term/DOID:0080488", "evidence": [ { "id": "0080488", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080488" } ], "weight": 0.0 }, { "disease_id": "DOID:1682", "name": "congenital heart disease", "description": "A physical disorder that is characterized by problems with the heart's structure that are present at birth.", "url": "https://disease-ontology.org/term/DOID:1682", "evidence": [ { "id": "1682", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1682" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity", "id": "GO:0003976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003976", "evidence": [ { "database": "UniProtKB", "id": "D3ZKE0", "url": "https://www.uniprot.org/uniprotkb/D3ZKE0" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "D3ZKE0", "url": "https://www.uniprot.org/uniprotkb/D3ZKE0" } ], "pmid": "" }, { "name": "transferase activity, transferring phosphorus-containing groups", "id": "GO:0016772", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016772", "evidence": [ { "database": "UniProtKB", "id": "D3ZKE0", "url": "https://www.uniprot.org/uniprotkb/D3ZKE0" } ], "pmid": "" } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "D3ZKE0", "url": "https://www.uniprot.org/uniprotkb/D3ZKE0" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "D3ZKE0", "url": "https://www.uniprot.org/uniprotkb/D3ZKE0" } ], "pmid": "" }, { "name": "UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase complex", "id": "GO:0070622", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070622", "evidence": [ { "database": "UniProtKB", "id": "D3ZKE0", "url": "https://www.uniprot.org/uniprotkb/D3ZKE0" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "D3ZKE0", "url": "https://www.uniprot.org/uniprotkb/D3ZKE0" } ], "pmid": "" } ], "biological_process": [ { "name": "lysosome organization", "id": "GO:0007040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007040", "evidence": [ { "database": "UniProtKB", "id": "D3ZKE0", "url": "https://www.uniprot.org/uniprotkb/D3ZKE0" } ], "pmid": "" }, { "name": "protein secretion", "id": "GO:0009306", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009306", "evidence": [ { "database": "UniProtKB", "id": "D3ZKE0", "url": "https://www.uniprot.org/uniprotkb/D3ZKE0" } ], "pmid": "" }, { "name": "N-glycan processing to lysosome", "id": "GO:0016256", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016256", "evidence": [ { "database": "UniProtKB", "id": "D3ZKE0", "url": "https://www.uniprot.org/uniprotkb/D3ZKE0" } ], "pmid": "" }, { "name": "carbohydrate phosphorylation", "id": "GO:0046835", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046835", "evidence": [ { "database": "UniProtKB", "id": "D3ZKE0", "url": "https://www.uniprot.org/uniprotkb/D3ZKE0" } ], "pmid": "" }, { "name": "secretion of lysosomal enzymes", "id": "GO:0033299", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033299", "evidence": [ { "database": "UniProtKB", "id": "D3ZKE0", "url": "https://www.uniprot.org/uniprotkb/D3ZKE0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "D3ZKE0-1", "start_pos": "806", "end_pos": "806", "site_lbl": "Thr806", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 806, "start_aa": "Thr", "end_pos": 806, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr806", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "D3ZKE0-1" }, { "uniprot_canonical_ac": "D3ZKQ1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZKQ1", "url": "https://www.uniprot.org/uniprotkb/D3ZKQ1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 312, "chemical_mass": 35165.0, "gene_names": "Or5w14;Olr581;Or5w14", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "D3ZKQ1", "url": "https://www.uniprot.org/uniprotkb/D3ZKQ1" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "D3ZKQ1", "url": "https://www.uniprot.org/uniprotkb/D3ZKQ1" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "D3ZKQ1", "url": "https://www.uniprot.org/uniprotkb/D3ZKQ1" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "D3ZKQ1", "url": "https://www.uniprot.org/uniprotkb/D3ZKQ1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZKQ1-1" }, { "uniprot_canonical_ac": "D3ZKV8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZKV8", "url": "https://www.uniprot.org/uniprotkb/D3ZKV8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 328, "chemical_mass": 35209.0, "gene_names": "Hoxc13;Hoxc13", "protein_name": "", "disease": [ { "disease_id": "DOID:0111656", "name": "ectodermal dysplasia 9", "description": "A pure hair and nail ectodermal dysplasia that has_material_basis_in homozygous or compound heterozygous mutation in the HOXC13 gene on chromosome 12q13.13.", "url": "https://disease-ontology.org/term/DOID:0111656", "evidence": [ { "id": "0111656", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111656" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "D3ZKV8", "url": "https://www.uniprot.org/uniprotkb/D3ZKV8" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "D3ZKV8", "url": "https://www.uniprot.org/uniprotkb/D3ZKV8" } ], "pmid": "" }, { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "D3ZKV8", "url": "https://www.uniprot.org/uniprotkb/D3ZKV8" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "D3ZKV8", "url": "https://www.uniprot.org/uniprotkb/D3ZKV8" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "D3ZKV8", "url": "https://www.uniprot.org/uniprotkb/D3ZKV8" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "D3ZKV8", "url": "https://www.uniprot.org/uniprotkb/D3ZKV8" } ], "pmid": "" }, { "name": "sequence-specific double-stranded DNA binding", "id": "GO:1990837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990837", "evidence": [ { "database": "UniProtKB", "id": "D3ZKV8", "url": "https://www.uniprot.org/uniprotkb/D3ZKV8" } ], "pmid": "" }, { "name": "DNA-binding transcription factor binding", "id": "GO:0140297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140297", "evidence": [ { "database": "UniProtKB", "id": "D3ZKV8", "url": "https://www.uniprot.org/uniprotkb/D3ZKV8" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D3ZKV8", "url": "https://www.uniprot.org/uniprotkb/D3ZKV8" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "D3ZKV8", "url": "https://www.uniprot.org/uniprotkb/D3ZKV8" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "D3ZKV8", "url": "https://www.uniprot.org/uniprotkb/D3ZKV8" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "D3ZKV8", "url": "https://www.uniprot.org/uniprotkb/D3ZKV8" } ], "pmid": "" }, { "name": "nail development", "id": "GO:0035878", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035878", "evidence": [ { "database": "UniProtKB", "id": "D3ZKV8", "url": "https://www.uniprot.org/uniprotkb/D3ZKV8" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "D3ZKV8", "url": "https://www.uniprot.org/uniprotkb/D3ZKV8" } ], "pmid": "" }, { "name": "anterior/posterior pattern specification", "id": "GO:0009952", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009952", "evidence": [ { "database": "UniProtKB", "id": "D3ZKV8", "url": "https://www.uniprot.org/uniprotkb/D3ZKV8" } ], "pmid": "" }, { "name": "hair follicle development", "id": "GO:0001942", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001942", "evidence": [ { "database": "UniProtKB", "id": "D3ZKV8", "url": "https://www.uniprot.org/uniprotkb/D3ZKV8" } ], "pmid": "" }, { "name": "anatomical structure morphogenesis", "id": "GO:0009653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009653", "evidence": [ { "database": "UniProtKB", "id": "D3ZKV8", "url": "https://www.uniprot.org/uniprotkb/D3ZKV8" } ], "pmid": "" }, { "name": "tongue morphogenesis", "id": "GO:0043587", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043587", "evidence": [ { "database": "UniProtKB", "id": "D3ZKV8", "url": "https://www.uniprot.org/uniprotkb/D3ZKV8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZKV8-1" }, { "uniprot_canonical_ac": "D3ZLI4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZLI4", "url": "https://www.uniprot.org/uniprotkb/D3ZLI4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 199, "chemical_mass": 23427.0, "gene_names": "LOC102550160;LOC102550160", "protein_name": "", "disease": [], "molecular_function": [ { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "D3ZLI4", "url": "https://www.uniprot.org/uniprotkb/D3ZLI4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZLI4-1" }, { "uniprot_canonical_ac": "D3ZLI9-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZLI9", "url": "https://www.uniprot.org/uniprotkb/D3ZLI9" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 772, "chemical_mass": 86838.0, "gene_names": "Pdzd4;Pdzd4;RGD1561214", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZLI9-1" }, { "uniprot_canonical_ac": "D3ZLM3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZLM3", "url": "https://www.uniprot.org/uniprotkb/D3ZLM3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 323, "chemical_mass": 35770.0, "gene_names": "Or52d1;Olr148;Or52d1", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "D3ZLM3", "url": "https://www.uniprot.org/uniprotkb/D3ZLM3" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "D3ZLM3", "url": "https://www.uniprot.org/uniprotkb/D3ZLM3" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "D3ZLM3", "url": "https://www.uniprot.org/uniprotkb/D3ZLM3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZLM3-1" }, { "uniprot_canonical_ac": "D3ZLZ3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZLZ3", "url": "https://www.uniprot.org/uniprotkb/D3ZLZ3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 367, "chemical_mass": 41402.0, "gene_names": "Cxhxorf66;LOC688842", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZLZ3-1" }, { "uniprot_canonical_ac": "D3ZM14-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZM14", "url": "https://www.uniprot.org/uniprotkb/D3ZM14" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1110, "chemical_mass": 120543.0, "gene_names": "Palb2;Palb2;RGD1304759", "protein_name": "", "disease": [ { "disease_id": "DOID:0050671", "name": "female breast cancer", "description": "A breast cancer that develops from breast tissue in females.", "url": "https://disease-ontology.org/term/DOID:0050671", "evidence": [ { "id": "0050671", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050671" } ], "weight": 0.0 }, { "disease_id": "DOID:0111094", "name": "Fanconi anemia complementation group N", "description": "A Fanconi anemia that has_material_basis_in compound heterozygous mutation in the PALB2 gene on chromosome 16p12.", "url": "https://disease-ontology.org/term/DOID:0111094", "evidence": [ { "id": "0111094", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111094" } ], "weight": 0.0 }, { "disease_id": "DOID:1793", "name": "pancreatic cancer", "description": "An endocrine gland cancer located_in the pancreas.", "url": "https://disease-ontology.org/term/DOID:1793", "evidence": [ { "id": "1793", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1793" } ], "weight": 0.0 }, { "disease_id": "DOID:5683", "name": "hereditary breast ovarian cancer syndrome", "description": "A syndrome characterized by the higher than normal tendency associated with BRCA1 and BRCA2 to develop breast and ovarian cancers in genetically related families.", "url": "https://disease-ontology.org/term/DOID:5683", "evidence": [ { "id": "5683", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5683" } ], "weight": 0.0 } ], "biological_process": [ { "name": "in utero embryonic development", "id": "GO:0001701", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001701", "evidence": [ { "database": "UniProtKB", "id": "D3ZM14", "url": "https://www.uniprot.org/uniprotkb/D3ZM14" } ], "pmid": "" }, { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "D3ZM14", "url": "https://www.uniprot.org/uniprotkb/D3ZM14" } ], "pmid": "" }, { "name": "multicellular organism growth", "id": "GO:0035264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035264", "evidence": [ { "database": "UniProtKB", "id": "D3ZM14", "url": "https://www.uniprot.org/uniprotkb/D3ZM14" } ], "pmid": "" }, { "name": "animal organ morphogenesis", "id": "GO:0009887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009887", "evidence": [ { "database": "UniProtKB", "id": "D3ZM14", "url": "https://www.uniprot.org/uniprotkb/D3ZM14" } ], "pmid": "" }, { "name": "somitogenesis", "id": "GO:0001756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001756", "evidence": [ { "database": "UniProtKB", "id": "D3ZM14", "url": "https://www.uniprot.org/uniprotkb/D3ZM14" } ], "pmid": "" }, { "name": "double-strand break repair via homologous recombination", "id": "GO:0000724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000724", "evidence": [ { "database": "UniProtKB", "id": "D3ZM14", "url": "https://www.uniprot.org/uniprotkb/D3ZM14" } ], "pmid": "" }, { "name": "embryonic organ development", "id": "GO:0048568", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048568", "evidence": [ { "database": "UniProtKB", "id": "D3ZM14", "url": "https://www.uniprot.org/uniprotkb/D3ZM14" } ], "pmid": "" }, { "name": "mesoderm development", "id": "GO:0007498", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007498", "evidence": [ { "database": "UniProtKB", "id": "D3ZM14", "url": "https://www.uniprot.org/uniprotkb/D3ZM14" } ], "pmid": "" }, { "name": "inner cell mass cell proliferation", "id": "GO:0001833", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001833", "evidence": [ { "database": "UniProtKB", "id": "D3ZM14", "url": "https://www.uniprot.org/uniprotkb/D3ZM14" } ], "pmid": "" }, { "name": "post-anal tail morphogenesis", "id": "GO:0036342", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036342", "evidence": [ { "database": "UniProtKB", "id": "D3ZM14", "url": "https://www.uniprot.org/uniprotkb/D3ZM14" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "D3ZM14", "url": "https://www.uniprot.org/uniprotkb/D3ZM14" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "D3ZM14", "url": "https://www.uniprot.org/uniprotkb/D3ZM14" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "D3ZM14", "url": "https://www.uniprot.org/uniprotkb/D3ZM14" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "D3ZM14", "url": "https://www.uniprot.org/uniprotkb/D3ZM14" } ], "pmid": "" }, { "name": "DNA repair complex", "id": "GO:1990391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990391", "evidence": [ { "database": "UniProtKB", "id": "D3ZM14", "url": "https://www.uniprot.org/uniprotkb/D3ZM14" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZM14-1" }, { "uniprot_canonical_ac": "D3ZM73-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZM73", "url": "https://www.uniprot.org/uniprotkb/D3ZM73" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 312, "chemical_mass": 34848.0, "gene_names": "Or7g41;Olr1126;Or7g41", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "D3ZM73", "url": "https://www.uniprot.org/uniprotkb/D3ZM73" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "D3ZM73", "url": "https://www.uniprot.org/uniprotkb/D3ZM73" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "D3ZM73", "url": "https://www.uniprot.org/uniprotkb/D3ZM73" } ], "pmid": "" } ], "biological_process": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "D3ZM73", "url": "https://www.uniprot.org/uniprotkb/D3ZM73" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZM73-1" }, { "uniprot_canonical_ac": "D3ZM99-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZM99", "url": "https://www.uniprot.org/uniprotkb/D3ZM99" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 204, "chemical_mass": 23193.0, "gene_names": "Rergl;RGD1560090;Rergl", "protein_name": "small monomeric GTPase", "disease": [], "molecular_function": [ { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "D3ZM99", "url": "https://www.uniprot.org/uniprotkb/D3ZM99" } ], "pmid": "" }, { "name": "G protein activity", "id": "GO:0003925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003925", "evidence": [ { "database": "UniProtKB", "id": "D3ZM99", "url": "https://www.uniprot.org/uniprotkb/D3ZM99" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZM99-1" }, { "uniprot_canonical_ac": "D3ZME2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZME2", "url": "https://www.uniprot.org/uniprotkb/D3ZME2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 861, "chemical_mass": 98114.0, "gene_names": "Vom2r57;LOC108348097;Vom2r56", "protein_name": "G-protein coupled receptors family 3 profile domain-containing protein", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "D3ZME2", "url": "https://www.uniprot.org/uniprotkb/D3ZME2" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "D3ZME2", "url": "https://www.uniprot.org/uniprotkb/D3ZME2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZME2-1" }, { "uniprot_canonical_ac": "D3ZMS5-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZMS5", "url": "https://www.uniprot.org/uniprotkb/D3ZMS5" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1714, "chemical_mass": 191848.0, "gene_names": "Tiam2;Tiam2", "protein_name": "", "disease": [ { "disease_id": "DOID:0070354", "name": "cataract 48", "description": "A cataract that has_material_basis_in homozygous mutation in the DNMBP gene on chromosome 10q24 and is characterized by infantile or early-childhood cataracts and visual impairment.", "url": "https://disease-ontology.org/term/DOID:0070354", "evidence": [ { "id": "0070354", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070354" } ], "weight": 0.0 }, { "disease_id": "DOID:0070444", "name": "neurodevelopmental disorder with language delay and seizures", "description": "An autosomal recessive intellectual developmental disorder characterized by early-onset seizures and global developmental delay with intellectual disability and speech delay that has_material_basis_in homozygous or compound heterozygous mutation in the TIAM1 gene on chromosome 21q22.", "url": "https://disease-ontology.org/term/DOID:0070444", "evidence": [ { "id": "0070444", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070444" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "D3ZMS5", "url": "https://www.uniprot.org/uniprotkb/D3ZMS5" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "D3ZMS5", "url": "https://www.uniprot.org/uniprotkb/D3ZMS5" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "D3ZMS5", "url": "https://www.uniprot.org/uniprotkb/D3ZMS5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "D3ZMS5", "url": "https://www.uniprot.org/uniprotkb/D3ZMS5" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "D3ZMS5", "url": "https://www.uniprot.org/uniprotkb/D3ZMS5" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "D3ZMS5", "url": "https://www.uniprot.org/uniprotkb/D3ZMS5" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "D3ZMS5", "url": "https://www.uniprot.org/uniprotkb/D3ZMS5" } ], "pmid": "" }, { "name": "fibrillar center", "id": "GO:0001650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001650", "evidence": [ { "database": "UniProtKB", "id": "D3ZMS5", "url": "https://www.uniprot.org/uniprotkb/D3ZMS5" } ], "pmid": "" } ], "biological_process": [ { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "D3ZMS5", "url": "https://www.uniprot.org/uniprotkb/D3ZMS5" } ], "pmid": "" }, { "name": "positive regulation of axonogenesis", "id": "GO:0050772", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050772", "evidence": [ { "database": "UniProtKB", "id": "D3ZMS5", "url": "https://www.uniprot.org/uniprotkb/D3ZMS5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "D3ZMS5-1", "start_pos": "231", "end_pos": "231", "site_lbl": "Thr231", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 231, "start_aa": "Thr", "end_pos": 231, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr231", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "D3ZMS5-1" }, { "uniprot_canonical_ac": "D3ZMX6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZMX6", "url": "https://www.uniprot.org/uniprotkb/D3ZMX6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 565, "chemical_mass": 60402.0, "gene_names": "Sntb2", "protein_name": "Beta-2-syntrophin", "disease": [ { "disease_id": "DOID:11723", "name": "Duchenne muscular dystrophy", "description": "A muscular dystrophy that has_material_basis_in X-linked mutations in the DMD gene found on the X chromosome. It is characterized by rapidly progressing muscle weakness and muscle atrophy initially involving the lower extremities and eventually affecting the whole body. It affects males whereas females can be carriers. The symptoms start before the age of six and may appear at infancy.", "url": "https://disease-ontology.org/term/DOID:11723", "evidence": [ { "id": "11723", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11723" } ], "weight": 0.0 }, { "disease_id": "DOID:9884", "name": "muscular dystrophy", "description": "A myopathy is characterized by progressive skeletal muscle weakness degeneration.", "url": "https://disease-ontology.org/term/DOID:9884", "evidence": [ { "id": "9884", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9884" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "dystrophin-associated glycoprotein complex", "id": "GO:0016010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016010", "evidence": [ { "database": "UniProtKB", "id": "D3ZMX6", "url": "https://www.uniprot.org/uniprotkb/D3ZMX6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "D3ZMX6", "url": "https://www.uniprot.org/uniprotkb/D3ZMX6" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "D3ZMX6", "url": "https://www.uniprot.org/uniprotkb/D3ZMX6" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "D3ZMX6", "url": "https://www.uniprot.org/uniprotkb/D3ZMX6" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "D3ZMX6", "url": "https://www.uniprot.org/uniprotkb/D3ZMX6" } ], "pmid": "" }, { "name": "transport vesicle membrane", "id": "GO:0030658", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030658", "evidence": [ { "database": "UniProtKB", "id": "D3ZMX6", "url": "https://www.uniprot.org/uniprotkb/D3ZMX6" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "D3ZMX6", "url": "https://www.uniprot.org/uniprotkb/D3ZMX6" } ], "pmid": "" }, { "name": "anchoring junction", "id": "GO:0070161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070161", "evidence": [ { "database": "UniProtKB", "id": "D3ZMX6", "url": "https://www.uniprot.org/uniprotkb/D3ZMX6" } ], "pmid": "" } ], "molecular_function": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "D3ZMX6", "url": "https://www.uniprot.org/uniprotkb/D3ZMX6" } ], "pmid": "" }, { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "D3ZMX6", "url": "https://www.uniprot.org/uniprotkb/D3ZMX6" } ], "pmid": "" }, { "name": "structural molecule activity", "id": "GO:0005198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005198", "evidence": [ { "database": "UniProtKB", "id": "D3ZMX6", "url": "https://www.uniprot.org/uniprotkb/D3ZMX6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZMX6-1" }, { "uniprot_canonical_ac": "D3ZNQ2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZNQ2", "url": "https://www.uniprot.org/uniprotkb/D3ZNQ2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 361, "chemical_mass": 39232.0, "gene_names": "Sbk3;LOC691408;Sbk3", "protein_name": "non-specific serine/threonine protein kinase", "disease": [], "molecular_function": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "D3ZNQ2", "url": "https://www.uniprot.org/uniprotkb/D3ZNQ2" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "D3ZNQ2", "url": "https://www.uniprot.org/uniprotkb/D3ZNQ2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "D3ZNQ2-1", "start_pos": "194", "end_pos": "194", "site_lbl": "Thr194", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 194, "start_aa": "Thr", "end_pos": 194, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr194", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "D3ZNQ2-1" }, { "uniprot_canonical_ac": "D3ZPB5-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZPB5", "url": "https://www.uniprot.org/uniprotkb/D3ZPB5" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 321, "chemical_mass": 35831.0, "gene_names": "Or7g24;Olr1118;Or7g24", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "D3ZPB5", "url": "https://www.uniprot.org/uniprotkb/D3ZPB5" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "D3ZPB5", "url": "https://www.uniprot.org/uniprotkb/D3ZPB5" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "D3ZPB5", "url": "https://www.uniprot.org/uniprotkb/D3ZPB5" } ], "pmid": "" } ], "biological_process": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "D3ZPB5", "url": "https://www.uniprot.org/uniprotkb/D3ZPB5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZPB5-1" }, { "uniprot_canonical_ac": "D3ZPV0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZPV0", "url": "https://www.uniprot.org/uniprotkb/D3ZPV0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 340, "chemical_mass": 39526.0, "gene_names": "Chst13;Chst13;RGD1562825", "protein_name": "Carbohydrate sulfotransferase", "disease": [], "molecular_function": [ { "name": "sulfotransferase activity", "id": "GO:0008146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008146", "evidence": [ { "database": "UniProtKB", "id": "D3ZPV0", "url": "https://www.uniprot.org/uniprotkb/D3ZPV0" } ], "pmid": "" }, { "name": "dermatan 4-sulfotransferase activity", "id": "GO:0001537", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001537", "evidence": [ { "database": "UniProtKB", "id": "D3ZPV0", "url": "https://www.uniprot.org/uniprotkb/D3ZPV0" } ], "pmid": "" }, { "name": "chondroitin 4-sulfotransferase activity", "id": "GO:0047756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047756", "evidence": [ { "database": "UniProtKB", "id": "D3ZPV0", "url": "https://www.uniprot.org/uniprotkb/D3ZPV0" } ], "pmid": "" } ], "biological_process": [ { "name": "carbohydrate biosynthetic process", "id": "GO:0016051", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016051", "evidence": [ { "database": "UniProtKB", "id": "D3ZPV0", "url": "https://www.uniprot.org/uniprotkb/D3ZPV0" } ], "pmid": "" }, { "name": "chondroitin sulfate proteoglycan biosynthetic process", "id": "GO:0050650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050650", "evidence": [ { "database": "UniProtKB", "id": "D3ZPV0", "url": "https://www.uniprot.org/uniprotkb/D3ZPV0" } ], "pmid": "" }, { "name": "proteoglycan biosynthetic process", "id": "GO:0030166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030166", "evidence": [ { "database": "UniProtKB", "id": "D3ZPV0", "url": "https://www.uniprot.org/uniprotkb/D3ZPV0" } ], "pmid": "" } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "D3ZPV0", "url": "https://www.uniprot.org/uniprotkb/D3ZPV0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZPV0-1" }, { "uniprot_canonical_ac": "D3ZPW4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZPW4", "url": "https://www.uniprot.org/uniprotkb/D3ZPW4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1165, "chemical_mass": 125020.0, "gene_names": "Ppp1r26;AABR07051376.1;Ppp1r26", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "D3ZPW4", "url": "https://www.uniprot.org/uniprotkb/D3ZPW4" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein phosphatase inhibitor activity", "id": "GO:0004864", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004864", "evidence": [ { "database": "UniProtKB", "id": "D3ZPW4", "url": "https://www.uniprot.org/uniprotkb/D3ZPW4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZPW4-1" }, { "uniprot_canonical_ac": "D3ZQB1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZQB1", "url": "https://www.uniprot.org/uniprotkb/D3ZQB1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 410, "chemical_mass": 43836.0, "gene_names": "Arid3c;Arid3c;RGD1560943", "protein_name": "AT-rich interactive domain-containing protein 3", "disease": [], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "D3ZQB1", "url": "https://www.uniprot.org/uniprotkb/D3ZQB1" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "D3ZQB1", "url": "https://www.uniprot.org/uniprotkb/D3ZQB1" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "D3ZQB1", "url": "https://www.uniprot.org/uniprotkb/D3ZQB1" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D3ZQB1", "url": "https://www.uniprot.org/uniprotkb/D3ZQB1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "D3ZQB1", "url": "https://www.uniprot.org/uniprotkb/D3ZQB1" } ], "pmid": "" }, { "name": "membrane raft", "id": "GO:0045121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045121", "evidence": [ { "database": "UniProtKB", "id": "D3ZQB1", "url": "https://www.uniprot.org/uniprotkb/D3ZQB1" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "D3ZQB1", "url": "https://www.uniprot.org/uniprotkb/D3ZQB1" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "D3ZQB1", "url": "https://www.uniprot.org/uniprotkb/D3ZQB1" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "D3ZQB1", "url": "https://www.uniprot.org/uniprotkb/D3ZQB1" } ], "pmid": "" }, { "name": "macrophage differentiation", "id": "GO:0030225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030225", "evidence": [ { "database": "UniProtKB", "id": "D3ZQB1", "url": "https://www.uniprot.org/uniprotkb/D3ZQB1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "D3ZQB1-1", "start_pos": "239", "end_pos": "239", "site_lbl": "Thr239", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 239, "start_aa": "Thr", "end_pos": 239, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr239", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "D3ZQB1-1", "start_pos": "335", "end_pos": "335", "site_lbl": "Thr335", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 335, "start_aa": "Thr", "end_pos": 335, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr335", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "D3ZQB1-1", "start_pos": "358", "end_pos": "358", "site_lbl": "Ala358", "weight": 0.0, "snv": [ { "sequence_org": "A", "sequence_mut": "S", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (NLA->NLS).", "chr_id": "5", "chr_pos": "61686446", "evidence": [ { "id": "rs3320496245", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3320496245" } ] } ] } ], "record_id": "D3ZQB1-1" }, { "uniprot_canonical_ac": "D3ZQB3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZQB3", "url": "https://www.uniprot.org/uniprotkb/D3ZQB3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 311, "chemical_mass": 35277.0, "gene_names": "Or5w19", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "D3ZQB3", "url": "https://www.uniprot.org/uniprotkb/D3ZQB3" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "D3ZQB3", "url": "https://www.uniprot.org/uniprotkb/D3ZQB3" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "D3ZQB3", "url": "https://www.uniprot.org/uniprotkb/D3ZQB3" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "D3ZQB3", "url": "https://www.uniprot.org/uniprotkb/D3ZQB3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZQB3-1" }, { "uniprot_canonical_ac": "D3ZQD3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZQD3", "url": "https://www.uniprot.org/uniprotkb/D3ZQD3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1010, "chemical_mass": 114637.0, "gene_names": "Ogdhl;Ogdhl", "protein_name": "2-oxoglutarate dehydrogenase-like, mitochondrial", "disease": [ { "disease_id": "DOID:0070468", "name": "Yoon-Bellen neurodevelopmental syndrome", "description": "A syndrome characterized by onset in the first decade of highly variable neurodevelopmental phenotypes including global developmental delay, intellectual disability, seizures, hearing and visual problems, and ataxia that has_material_basis_in homozygous or compound heterozygous mutation in the OGDHL gene on chromosome 10q11.23.", "url": "https://disease-ontology.org/term/DOID:0070468", "evidence": [ { "id": "0070468", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070468" } ], "weight": 0.0 }, { "disease_id": "DOID:0081326", "name": "oxoglutarate dehydrogenase deficiency", "description": "An amino acid metabolic disorder that is characterized by infantile and pediatric onset basal ganglia-associated movement disorders, hypotonia, developmental delays, ataxia, and seizures and that has_material_basis_in homozygous mutation in the oxoglutarate dehydrogenase gene (OGDH) on chromosome 7p13.", "url": "https://disease-ontology.org/term/DOID:0081326", "evidence": [ { "id": "0081326", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081326" } ], "weight": 0.0 }, { "disease_id": "DOID:12930", "name": "dilated cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by an an enlarged heart and damage to the myocardium causing the heart to pump blood inefficiently.", "url": "https://disease-ontology.org/term/DOID:12930", "evidence": [ { "id": "12930", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12930" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "D3ZQD3", "url": "https://www.uniprot.org/uniprotkb/D3ZQD3" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "D3ZQD3", "url": "https://www.uniprot.org/uniprotkb/D3ZQD3" } ], "pmid": "" }, { "name": "oxoglutarate dehydrogenase complex", "id": "GO:0045252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045252", "evidence": [ { "database": "UniProtKB", "id": "D3ZQD3", "url": "https://www.uniprot.org/uniprotkb/D3ZQD3" } ], "pmid": "" } ], "biological_process": [ { "name": "tricarboxylic acid cycle", "id": "GO:0006099", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006099", "evidence": [ { "database": "UniProtKB", "id": "D3ZQD3", "url": "https://www.uniprot.org/uniprotkb/D3ZQD3" } ], "pmid": "" }, { "name": "2-oxoglutarate metabolic process", "id": "GO:0006103", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006103", "evidence": [ { "database": "UniProtKB", "id": "D3ZQD3", "url": "https://www.uniprot.org/uniprotkb/D3ZQD3" } ], "pmid": "" }, { "name": "glycolytic process", "id": "GO:0006096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006096", "evidence": [ { "database": "UniProtKB", "id": "D3ZQD3", "url": "https://www.uniprot.org/uniprotkb/D3ZQD3" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "D3ZQD3", "url": "https://www.uniprot.org/uniprotkb/D3ZQD3" } ], "pmid": "" }, { "name": "thiamine pyrophosphate binding", "id": "GO:0030976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030976", "evidence": [ { "database": "UniProtKB", "id": "D3ZQD3", "url": "https://www.uniprot.org/uniprotkb/D3ZQD3" } ], "pmid": "" }, { "name": "oxoglutarate dehydrogenase (succinyl-transferring) activity", "id": "GO:0004591", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004591", "evidence": [ { "database": "UniProtKB", "id": "D3ZQD3", "url": "https://www.uniprot.org/uniprotkb/D3ZQD3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZQD3-1" }, { "uniprot_canonical_ac": "D3ZQE8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZQE8", "url": "https://www.uniprot.org/uniprotkb/D3ZQE8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1209, "chemical_mass": 137458.0, "gene_names": "Xpo5", "protein_name": "Exportin-5", "disease": [ { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:2671", "name": "transitional cell carcinoma", "description": "A carcinoma that derives_from transitional epithelial cells.", "url": "https://disease-ontology.org/term/DOID:2671", "evidence": [ { "id": "2671", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2671" } ], "weight": 0.0 }, { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 }, { "disease_id": "DOID:5409", "name": "lung small cell carcinoma", "description": "A lung carcinoma that has_material_basis_in primitive-appearing cells that are smaller than normal cells and is located_in the lung.", "url": "https://disease-ontology.org/term/DOID:5409", "evidence": [ { "id": "5409", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5409" } ], "weight": 0.0 }, { "disease_id": "DOID:5426", "name": "primary ovarian insufficiency", "description": "An ovarian disease where ovaries do not produce estrogen despite high levels of circulating gonadotropins in women under 40.", "url": "https://disease-ontology.org/term/DOID:5426", "evidence": [ { "id": "5426", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5426" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 }, { "disease_id": "DOID:9538", "name": "multiple myeloma", "description": "A myeloid neoplasm that is located_in the plasma cells in bone marrow.", "url": "https://disease-ontology.org/term/DOID:9538", "evidence": [ { "id": "9538", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9538" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "RISC complex binding", "id": "GO:1905172", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905172", "evidence": [ { "database": "UniProtKB", "id": "D3ZQE8", "url": "https://www.uniprot.org/uniprotkb/D3ZQE8" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "D3ZQE8", "url": "https://www.uniprot.org/uniprotkb/D3ZQE8" } ], "pmid": "" }, { "name": "tRNA binding", "id": "GO:0000049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000049", "evidence": [ { "database": "UniProtKB", "id": "D3ZQE8", "url": "https://www.uniprot.org/uniprotkb/D3ZQE8" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "D3ZQE8", "url": "https://www.uniprot.org/uniprotkb/D3ZQE8" } ], "pmid": "" }, { "name": "pre-miRNA binding", "id": "GO:0070883", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070883", "evidence": [ { "database": "UniProtKB", "id": "D3ZQE8", "url": "https://www.uniprot.org/uniprotkb/D3ZQE8" } ], "pmid": "" }, { "name": "nuclear export signal receptor activity", "id": "GO:0005049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005049", "evidence": [ { "database": "UniProtKB", "id": "D3ZQE8", "url": "https://www.uniprot.org/uniprotkb/D3ZQE8" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "D3ZQE8", "url": "https://www.uniprot.org/uniprotkb/D3ZQE8" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D3ZQE8", "url": "https://www.uniprot.org/uniprotkb/D3ZQE8" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "D3ZQE8", "url": "https://www.uniprot.org/uniprotkb/D3ZQE8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "D3ZQE8", "url": "https://www.uniprot.org/uniprotkb/D3ZQE8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "D3ZQE8", "url": "https://www.uniprot.org/uniprotkb/D3ZQE8" } ], "pmid": "" }, { "name": "RISC complex", "id": "GO:0016442", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016442", "evidence": [ { "database": "UniProtKB", "id": "D3ZQE8", "url": "https://www.uniprot.org/uniprotkb/D3ZQE8" } ], "pmid": "" }, { "name": "RNA nuclear export complex", "id": "GO:0042565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042565", "evidence": [ { "database": "UniProtKB", "id": "D3ZQE8", "url": "https://www.uniprot.org/uniprotkb/D3ZQE8" } ], "pmid": "" } ], "biological_process": [ { "name": "protein export from nucleus", "id": "GO:0006611", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006611", "evidence": [ { "database": "UniProtKB", "id": "D3ZQE8", "url": "https://www.uniprot.org/uniprotkb/D3ZQE8" } ], "pmid": "" }, { "name": "pre-miRNA export from nucleus", "id": "GO:0035281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035281", "evidence": [ { "database": "UniProtKB", "id": "D3ZQE8", "url": "https://www.uniprot.org/uniprotkb/D3ZQE8" } ], "pmid": "" }, { "name": "RNA export from nucleus", "id": "GO:0006405", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006405", "evidence": [ { "database": "UniProtKB", "id": "D3ZQE8", "url": "https://www.uniprot.org/uniprotkb/D3ZQE8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZQE8-1" }, { "uniprot_canonical_ac": "D3ZQG3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZQG3", "url": "https://www.uniprot.org/uniprotkb/D3ZQG3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 388, "chemical_mass": 41899.0, "gene_names": "Rhbdd2", "protein_name": "Rhomboid domain-containing protein 2", "disease": [], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "D3ZQG3", "url": "https://www.uniprot.org/uniprotkb/D3ZQG3" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "D3ZQG3", "url": "https://www.uniprot.org/uniprotkb/D3ZQG3" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "D3ZQG3", "url": "https://www.uniprot.org/uniprotkb/D3ZQG3" } ], "pmid": "" } ], "molecular_function": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "D3ZQG3", "url": "https://www.uniprot.org/uniprotkb/D3ZQG3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "D3ZQG3-1", "start_pos": "283", "end_pos": "283", "site_lbl": "Thr283", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 283, "start_aa": "Thr", "end_pos": 283, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr283", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "D3ZQG3-1" }, { "uniprot_canonical_ac": "D3ZQI7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZQI7", "url": "https://www.uniprot.org/uniprotkb/D3ZQI7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 782, "chemical_mass": 86234.0, "gene_names": "Zbtb47;RGD1562434;Zbtb47;Zfp651", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D3ZQI7", "url": "https://www.uniprot.org/uniprotkb/D3ZQI7" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "D3ZQI7", "url": "https://www.uniprot.org/uniprotkb/D3ZQI7" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "D3ZQI7", "url": "https://www.uniprot.org/uniprotkb/D3ZQI7" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "D3ZQI7", "url": "https://www.uniprot.org/uniprotkb/D3ZQI7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZQI7-1" }, { "uniprot_canonical_ac": "D3ZQM4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZQM4", "url": "https://www.uniprot.org/uniprotkb/D3ZQM4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 312, "chemical_mass": 35608.0, "gene_names": "Or52e51;Olr86;Or52e51", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "D3ZQM4", "url": "https://www.uniprot.org/uniprotkb/D3ZQM4" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "D3ZQM4", "url": "https://www.uniprot.org/uniprotkb/D3ZQM4" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "D3ZQM4", "url": "https://www.uniprot.org/uniprotkb/D3ZQM4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZQM4-1" }, { "uniprot_canonical_ac": "D3ZQW1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1410, "chemical_mass": 157213.0, "gene_names": "Blm;Blm", "protein_name": "RecQ-like DNA helicase BLM", "disease": [ { "disease_id": "DOID:2717", "name": "Bloom syndrome", "description": "A syndrome characterized by sun sensitivity, short stature, predisposition to the development of cancer and genomic instability.", "url": "https://disease-ontology.org/term/DOID:2717", "evidence": [ { "id": "2717", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2717" } ], "weight": 0.0 }, { "disease_id": "DOID:5688", "name": "Werner syndrome", "description": "A progeroid syndrome characterized by premature aging and age-related phenotypes such as atherosclerosis, arteriosclerosis, cataracts, osteoporosis, soft tissue calcification, premature thinning, graying, and loss of hair, as well as a high incidence of some types of cancers and that has_material_basis_in mutations in the WRN gene, on chromosome 8.", "url": "https://disease-ontology.org/term/DOID:5688", "evidence": [ { "id": "5688", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5688" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "3'-5' DNA helicase activity", "id": "GO:0043138", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043138", "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "pmid": "" }, { "name": "p53 binding", "id": "GO:0002039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002039", "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "pmid": "" }, { "name": "single-stranded DNA binding", "id": "GO:0003697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003697", "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "pmid": "" }, { "name": "helicase activity", "id": "GO:0004386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004386", "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "pmid": "" }, { "name": "four-way junction DNA binding", "id": "GO:0000400", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000400", "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "pmid": "" }, { "name": "Y-form DNA binding", "id": "GO:0000403", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000403", "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "pmid": "" }, { "name": "bubble DNA binding", "id": "GO:0000405", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000405", "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "pmid": "" }, { "name": "DNA helicase activity", "id": "GO:0003678", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003678", "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "pmid": "" }, { "name": "ATP-dependent activity, acting on DNA", "id": "GO:0008094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008094", "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "pmid": "" }, { "name": "four-way junction helicase activity", "id": "GO:0009378", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009378", "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "pmid": "" }, { "name": "G-quadruplex DNA binding", "id": "GO:0051880", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051880", "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "pmid": "" }, { "name": "forked DNA-dependent helicase activity", "id": "GO:0061749", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061749", "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "pmid": "" }, { "name": "telomeric D-loop binding", "id": "GO:0061821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061821", "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "pmid": "" }, { "name": "telomeric G-quadruplex DNA binding", "id": "GO:0061849", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061849", "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "pmid": "" }, { "name": "8-hydroxy-2'-deoxyguanosine DNA binding", "id": "GO:1905773", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905773", "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "pmid": "" }, { "name": "hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides", "id": "GO:0016818", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016818", "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "pmid": "" }, { "name": "DNA/DNA annealing activity", "id": "GO:1990814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990814", "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "pmid": "" }, { "name": "nuclear matrix", "id": "GO:0016363", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016363", "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "pmid": "" }, { "name": "male germ cell nucleus", "id": "GO:0001673", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001673", "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "pmid": "" }, { "name": "PML body", "id": "GO:0016605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016605", "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "pmid": "" }, { "name": "nuclear chromosome", "id": "GO:0000228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000228", "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "pmid": "" }, { "name": "replication fork", "id": "GO:0005657", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005657", "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "pmid": "" }, { "name": "pronucleus", "id": "GO:0045120", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045120", "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "pmid": "" }, { "name": "lateral element", "id": "GO:0000800", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000800", "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "pmid": "" }, { "name": "RecQ family helicase-topoisomerase III complex", "id": "GO:0031422", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031422", "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "pmid": "" }, { "name": "protein complex oligomerization", "id": "GO:0051259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051259", "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "pmid": "" }, { "name": "protein homooligomerization", "id": "GO:0051260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051260", "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "pmid": "" }, { "name": "cellular response to xenobiotic stimulus", "id": "GO:0071466", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071466", "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "pmid": "" }, { "name": "telomere maintenance", "id": "GO:0000723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000723", "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "pmid": "" }, { "name": "DNA replication", "id": "GO:0006260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006260", "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "pmid": "" }, { "name": "negative regulation of thymocyte apoptotic process", "id": "GO:0070244", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070244", "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "pmid": "" }, { "name": "alpha-beta T cell differentiation", "id": "GO:0046632", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046632", "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "pmid": "" }, { "name": "regulation of cyclin-dependent protein serine/threonine kinase activity", "id": "GO:0000079", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000079", "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "pmid": "" }, { "name": "double-strand break repair via homologous recombination", "id": "GO:0000724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000724", "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "pmid": "" }, { "name": "response to X-ray", "id": "GO:0010165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010165", "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "pmid": "" }, { "name": "negative regulation of mitotic recombination", "id": "GO:0045950", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045950", "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "pmid": "" }, { "name": "cellular response to ionizing radiation", "id": "GO:0071479", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071479", "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "pmid": "" }, { "name": "mitotic G2 DNA damage checkpoint signaling", "id": "GO:0007095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007095", "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "pmid": "" }, { "name": "negative regulation of DNA recombination", "id": "GO:0045910", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045910", "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "pmid": "" }, { "name": "negative regulation of cell division", "id": "GO:0051782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051782", "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "pmid": "" }, { "name": "telomeric D-loop disassembly", "id": "GO:0061820", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061820", "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "pmid": "" }, { "name": "cellular response to hydroxyurea", "id": "GO:0072711", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072711", "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "pmid": "" }, { "name": "cellular response to camptothecin", "id": "GO:0072757", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072757", "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "pmid": "" }, { "name": "DNA double-strand break processing", "id": "GO:0000729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000729", "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "pmid": "" }, { "name": "replication fork processing", "id": "GO:0031297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031297", "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "pmid": "" }, { "name": "positive regulation of alpha-beta T cell proliferation", "id": "GO:0046641", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046641", "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "pmid": "" }, { "name": "chromosome organization", "id": "GO:0051276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051276", "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "pmid": "" }, { "name": "resolution of DNA recombination intermediates", "id": "GO:0071139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071139", "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "pmid": "" }, { "name": "positive regulation of double-strand break repair via homologous recombination", "id": "GO:1905168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905168", "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "pmid": "" }, { "name": "DNA geometric change", "id": "GO:0032392", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032392", "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "pmid": "" }, { "name": "replication-born double-strand break repair via sister chromatid exchange", "id": "GO:1990414", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990414", "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "pmid": "" }, { "name": "DNA recombination", "id": "GO:0006310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006310", "evidence": [ { "database": "UniProtKB", "id": "D3ZQW1", "url": "https://www.uniprot.org/uniprotkb/D3ZQW1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZQW1-1" }, { "uniprot_canonical_ac": "D3ZRA6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZRA6", "url": "https://www.uniprot.org/uniprotkb/D3ZRA6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1931, "chemical_mass": 201696.0, "gene_names": "Tnrc6c;RGD1310027;Tnrc6c", "protein_name": "Trinucleotide repeat-containing gene 6C protein", "disease": [], "biological_process": [ { "name": "embryonic hemopoiesis", "id": "GO:0035162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035162", "evidence": [ { "database": "UniProtKB", "id": "D3ZRA6", "url": "https://www.uniprot.org/uniprotkb/D3ZRA6" } ], "pmid": "" }, { "name": "regulation of translation", "id": "GO:0006417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006417", "evidence": [ { "database": "UniProtKB", "id": "D3ZRA6", "url": "https://www.uniprot.org/uniprotkb/D3ZRA6" } ], "pmid": "" }, { "name": "regulation of miRNA-mediated gene silencing", "id": "GO:0060964", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060964", "evidence": [ { "database": "UniProtKB", "id": "D3ZRA6", "url": "https://www.uniprot.org/uniprotkb/D3ZRA6" } ], "pmid": "" }, { "name": "transforming growth factor beta receptor signaling pathway", "id": "GO:0007179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007179", "evidence": [ { "database": "UniProtKB", "id": "D3ZRA6", "url": "https://www.uniprot.org/uniprotkb/D3ZRA6" } ], "pmid": "" }, { "name": "positive regulation of nuclear-transcribed mRNA poly(A) tail shortening", "id": "GO:0060213", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060213", "evidence": [ { "database": "UniProtKB", "id": "D3ZRA6", "url": "https://www.uniprot.org/uniprotkb/D3ZRA6" } ], "pmid": "" }, { "name": "positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay", "id": "GO:1900153", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900153", "evidence": [ { "database": "UniProtKB", "id": "D3ZRA6", "url": "https://www.uniprot.org/uniprotkb/D3ZRA6" } ], "pmid": "" }, { "name": "miRNA-mediated post-transcriptional gene silencing", "id": "GO:0035195", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035195", "evidence": [ { "database": "UniProtKB", "id": "D3ZRA6", "url": "https://www.uniprot.org/uniprotkb/D3ZRA6" } ], "pmid": "" }, { "name": "endoderm development", "id": "GO:0007492", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007492", "evidence": [ { "database": "UniProtKB", "id": "D3ZRA6", "url": "https://www.uniprot.org/uniprotkb/D3ZRA6" } ], "pmid": "" }, { "name": "embryonic organ development", "id": "GO:0048568", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048568", "evidence": [ { "database": "UniProtKB", "id": "D3ZRA6", "url": "https://www.uniprot.org/uniprotkb/D3ZRA6" } ], "pmid": "" }, { "name": "lung saccule development", "id": "GO:0060430", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060430", "evidence": [ { "database": "UniProtKB", "id": "D3ZRA6", "url": "https://www.uniprot.org/uniprotkb/D3ZRA6" } ], "pmid": "" }, { "name": "endoderm formation", "id": "GO:0001706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001706", "evidence": [ { "database": "UniProtKB", "id": "D3ZRA6", "url": "https://www.uniprot.org/uniprotkb/D3ZRA6" } ], "pmid": "" }, { "name": "regulatory ncRNA-mediated gene silencing", "id": "GO:0031047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031047", "evidence": [ { "database": "UniProtKB", "id": "D3ZRA6", "url": "https://www.uniprot.org/uniprotkb/D3ZRA6" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "D3ZRA6", "url": "https://www.uniprot.org/uniprotkb/D3ZRA6" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "D3ZRA6", "url": "https://www.uniprot.org/uniprotkb/D3ZRA6" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "D3ZRA6", "url": "https://www.uniprot.org/uniprotkb/D3ZRA6" } ], "pmid": "" }, { "name": "P-body", "id": "GO:0000932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000932", "evidence": [ { "database": "UniProtKB", "id": "D3ZRA6", "url": "https://www.uniprot.org/uniprotkb/D3ZRA6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZRA6-1" }, { "uniprot_canonical_ac": "D3ZRF0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZRF0", "url": "https://www.uniprot.org/uniprotkb/D3ZRF0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1116, "chemical_mass": 128112.0, "gene_names": "Rptn;Rptn", "protein_name": "", "disease": [], "molecular_function": [ { "name": "transition metal ion binding", "id": "GO:0046914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046914", "evidence": [ { "database": "UniProtKB", "id": "D3ZRF0", "url": "https://www.uniprot.org/uniprotkb/D3ZRF0" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "D3ZRF0", "url": "https://www.uniprot.org/uniprotkb/D3ZRF0" } ], "pmid": "" } ], "cellular_component": [ { "name": "cornified envelope", "id": "GO:0001533", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001533", "evidence": [ { "database": "UniProtKB", "id": "D3ZRF0", "url": "https://www.uniprot.org/uniprotkb/D3ZRF0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZRF0-1" }, { "uniprot_canonical_ac": "D3ZRJ6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZRJ6", "url": "https://www.uniprot.org/uniprotkb/D3ZRJ6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 319, "chemical_mass": 35504.0, "gene_names": "Gpa33;Gpa33", "protein_name": "Cell surface A33 antigen", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "D3ZRJ6", "url": "https://www.uniprot.org/uniprotkb/D3ZRJ6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZRJ6-1" }, { "uniprot_canonical_ac": "D3ZRU9-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZRU9", "url": "https://www.uniprot.org/uniprotkb/D3ZRU9" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1249, "chemical_mass": 136777.0, "gene_names": "Rev1", "protein_name": "Translesion synthesis protein REV1", "disease": [], "molecular_function": [ { "name": "DNA-directed DNA polymerase activity", "id": "GO:0003887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003887", "evidence": [ { "database": "UniProtKB", "id": "D3ZRU9", "url": "https://www.uniprot.org/uniprotkb/D3ZRU9" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "D3ZRU9", "url": "https://www.uniprot.org/uniprotkb/D3ZRU9" } ], "pmid": "" }, { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "D3ZRU9", "url": "https://www.uniprot.org/uniprotkb/D3ZRU9" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "D3ZRU9", "url": "https://www.uniprot.org/uniprotkb/D3ZRU9" } ], "pmid": "" }, { "name": "damaged DNA binding", "id": "GO:0003684", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003684", "evidence": [ { "database": "UniProtKB", "id": "D3ZRU9", "url": "https://www.uniprot.org/uniprotkb/D3ZRU9" } ], "pmid": "" }, { "name": "ubiquitin binding", "id": "GO:0043130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043130", "evidence": [ { "database": "UniProtKB", "id": "D3ZRU9", "url": "https://www.uniprot.org/uniprotkb/D3ZRU9" } ], "pmid": "" }, { "name": "deoxycytidyl transferase activity", "id": "GO:0017125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017125", "evidence": [ { "database": "UniProtKB", "id": "D3ZRU9", "url": "https://www.uniprot.org/uniprotkb/D3ZRU9" } ], "pmid": "" }, { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "D3ZRU9", "url": "https://www.uniprot.org/uniprotkb/D3ZRU9" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA biosynthetic process", "id": "GO:0071897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071897", "evidence": [ { "database": "UniProtKB", "id": "D3ZRU9", "url": "https://www.uniprot.org/uniprotkb/D3ZRU9" } ], "pmid": "" }, { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "D3ZRU9", "url": "https://www.uniprot.org/uniprotkb/D3ZRU9" } ], "pmid": "" }, { "name": "somatic hypermutation of immunoglobulin genes", "id": "GO:0016446", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016446", "evidence": [ { "database": "UniProtKB", "id": "D3ZRU9", "url": "https://www.uniprot.org/uniprotkb/D3ZRU9" } ], "pmid": "" }, { "name": "translesion synthesis", "id": "GO:0019985", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019985", "evidence": [ { "database": "UniProtKB", "id": "D3ZRU9", "url": "https://www.uniprot.org/uniprotkb/D3ZRU9" } ], "pmid": "" }, { "name": "error-prone translesion synthesis", "id": "GO:0042276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042276", "evidence": [ { "database": "UniProtKB", "id": "D3ZRU9", "url": "https://www.uniprot.org/uniprotkb/D3ZRU9" } ], "pmid": "" }, { "name": "error-free translesion synthesis", "id": "GO:0070987", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070987", "evidence": [ { "database": "UniProtKB", "id": "D3ZRU9", "url": "https://www.uniprot.org/uniprotkb/D3ZRU9" } ], "pmid": "" } ], "cellular_component": [ { "name": "nuclear replication fork", "id": "GO:0043596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043596", "evidence": [ { "database": "UniProtKB", "id": "D3ZRU9", "url": "https://www.uniprot.org/uniprotkb/D3ZRU9" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D3ZRU9", "url": "https://www.uniprot.org/uniprotkb/D3ZRU9" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "D3ZRU9", "url": "https://www.uniprot.org/uniprotkb/D3ZRU9" } ], "pmid": "" }, { "name": "site of DNA damage", "id": "GO:0090734", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090734", "evidence": [ { "database": "UniProtKB", "id": "D3ZRU9", "url": "https://www.uniprot.org/uniprotkb/D3ZRU9" } ], "pmid": "" }, { "name": "site of double-strand break", "id": "GO:0035861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035861", "evidence": [ { "database": "UniProtKB", "id": "D3ZRU9", "url": "https://www.uniprot.org/uniprotkb/D3ZRU9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZRU9-1" }, { "uniprot_canonical_ac": "D3ZSD3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZSD3", "url": "https://www.uniprot.org/uniprotkb/D3ZSD3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 413, "chemical_mass": 45318.0, "gene_names": "Gabpb2;Gabpb2;RGD1565234", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D3ZSD3", "url": "https://www.uniprot.org/uniprotkb/D3ZSD3" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "D3ZSD3", "url": "https://www.uniprot.org/uniprotkb/D3ZSD3" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "D3ZSD3", "url": "https://www.uniprot.org/uniprotkb/D3ZSD3" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "D3ZSD3", "url": "https://www.uniprot.org/uniprotkb/D3ZSD3" } ], "pmid": "" } ], "molecular_function": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "D3ZSD3", "url": "https://www.uniprot.org/uniprotkb/D3ZSD3" } ], "pmid": "" }, { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "D3ZSD3", "url": "https://www.uniprot.org/uniprotkb/D3ZSD3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZSD3-1" }, { "uniprot_canonical_ac": "D3ZSG2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZSG2", "url": "https://www.uniprot.org/uniprotkb/D3ZSG2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 2999, "chemical_mass": 343654.0, "gene_names": "Trank1;RGD1563130;Trank1", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "D3ZSG2-1", "start_pos": "1720", "end_pos": "1720", "site_lbl": "Thr1720", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1720, "start_aa": "Thr", "end_pos": 1720, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1720", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "D3ZSG2-1", "start_pos": "22", "end_pos": "22", "site_lbl": "Thr22", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 22, "start_aa": "Thr", "end_pos": 22, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr22", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "D3ZSG2-1", "start_pos": "61", "end_pos": "61", "site_lbl": "Thr61", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 61, "start_aa": "Thr", "end_pos": 61, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr61", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "D3ZSG2-1" }, { "uniprot_canonical_ac": "D3ZSH6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZSH6", "url": "https://www.uniprot.org/uniprotkb/D3ZSH6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 133, "chemical_mass": 14912.0, "gene_names": "LOC108348601", "protein_name": "", "disease": [ { "disease_id": "DOID:12449", "name": "aplastic anemia", "description": "A normocytic anemia that is characterized by a deficiency of red blood cells, white blood cells and platelets produced by bone marrow.", "url": "https://disease-ontology.org/term/DOID:12449", "evidence": [ { "id": "12449", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12449" } ], "weight": 0.0 }, { "disease_id": "DOID:1339", "name": "Diamond-Blackfan anemia", "description": "A pure red-cell aplasia that is characterized by anemia (low red blood cell counts) with decreased erythroid progenitors in the bone marrow and has_material_basis_insufficient levels of red blood cells due to bone marrow dysfunction.", "url": "https://disease-ontology.org/term/DOID:1339", "evidence": [ { "id": "1339", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1339" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "D3ZSH6", "url": "https://www.uniprot.org/uniprotkb/D3ZSH6" } ], "pmid": "" }, { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "D3ZSH6", "url": "https://www.uniprot.org/uniprotkb/D3ZSH6" } ], "pmid": "" } ], "biological_process": [ { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "D3ZSH6", "url": "https://www.uniprot.org/uniprotkb/D3ZSH6" } ], "pmid": "" }, { "name": "ribosomal small subunit assembly", "id": "GO:0000028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000028", "evidence": [ { "database": "UniProtKB", "id": "D3ZSH6", "url": "https://www.uniprot.org/uniprotkb/D3ZSH6" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosolic small ribosomal subunit", "id": "GO:0022627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022627", "evidence": [ { "database": "UniProtKB", "id": "D3ZSH6", "url": "https://www.uniprot.org/uniprotkb/D3ZSH6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZSH6-1" }, { "uniprot_canonical_ac": "D3ZSI3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZSI3", "url": "https://www.uniprot.org/uniprotkb/D3ZSI3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 320, "chemical_mass": 35670.0, "gene_names": "Or5an6;Olr336;Or5an6", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "D3ZSI3", "url": "https://www.uniprot.org/uniprotkb/D3ZSI3" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "D3ZSI3", "url": "https://www.uniprot.org/uniprotkb/D3ZSI3" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "D3ZSI3", "url": "https://www.uniprot.org/uniprotkb/D3ZSI3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZSI3-1" }, { "uniprot_canonical_ac": "D3ZSN2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZSN2", "url": "https://www.uniprot.org/uniprotkb/D3ZSN2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 268, "chemical_mass": 29237.0, "gene_names": "Hoxd12;Hoxd12", "protein_name": "", "disease": [ { "disease_id": "DOID:11836", "name": "clubfoot", "description": "A bone development disease where one or both are inclined inwards, axially rotated outwards, and pointing downwards with concomitant soft tissue abnormalities.", "url": "https://disease-ontology.org/term/DOID:11836", "evidence": [ { "id": "11836", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11836" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D3ZSN2", "url": "https://www.uniprot.org/uniprotkb/D3ZSN2" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "D3ZSN2", "url": "https://www.uniprot.org/uniprotkb/D3ZSN2" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "D3ZSN2", "url": "https://www.uniprot.org/uniprotkb/D3ZSN2" } ], "pmid": "" }, { "name": "skeletal system development", "id": "GO:0001501", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001501", "evidence": [ { "database": "UniProtKB", "id": "D3ZSN2", "url": "https://www.uniprot.org/uniprotkb/D3ZSN2" } ], "pmid": "" }, { "name": "embryonic digit morphogenesis", "id": "GO:0042733", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042733", "evidence": [ { "database": "UniProtKB", "id": "D3ZSN2", "url": "https://www.uniprot.org/uniprotkb/D3ZSN2" } ], "pmid": "" }, { "name": "pattern specification process", "id": "GO:0007389", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007389", "evidence": [ { "database": "UniProtKB", "id": "D3ZSN2", "url": "https://www.uniprot.org/uniprotkb/D3ZSN2" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "D3ZSN2", "url": "https://www.uniprot.org/uniprotkb/D3ZSN2" } ], "pmid": "" }, { "name": "sequence-specific double-stranded DNA binding", "id": "GO:1990837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990837", "evidence": [ { "database": "UniProtKB", "id": "D3ZSN2", "url": "https://www.uniprot.org/uniprotkb/D3ZSN2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "D3ZSN2-1", "start_pos": "54", "end_pos": "54", "site_lbl": "Thr54", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 54, "start_aa": "Thr", "end_pos": 54, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr54", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "D3ZSN2-1" }, { "uniprot_canonical_ac": "D3ZT71-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZT71", "url": "https://www.uniprot.org/uniprotkb/D3ZT71" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 434, "chemical_mass": 46734.0, "gene_names": "Bcl2l13;Bcl2l13", "protein_name": "", "disease": [], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "D3ZT71", "url": "https://www.uniprot.org/uniprotkb/D3ZT71" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "D3ZT71", "url": "https://www.uniprot.org/uniprotkb/D3ZT71" } ], "pmid": "" } ], "biological_process": [ { "name": "ATP biosynthetic process", "id": "GO:0006754", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006754", "evidence": [ { "database": "UniProtKB", "id": "D3ZT71", "url": "https://www.uniprot.org/uniprotkb/D3ZT71" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "D3ZT71", "url": "https://www.uniprot.org/uniprotkb/D3ZT71" } ], "pmid": "" }, { "name": "fat cell differentiation", "id": "GO:0045444", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045444", "evidence": [ { "database": "UniProtKB", "id": "D3ZT71", "url": "https://www.uniprot.org/uniprotkb/D3ZT71" } ], "pmid": "" }, { "name": "regulation of apoptotic process", "id": "GO:0042981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042981", "evidence": [ { "database": "UniProtKB", "id": "D3ZT71", "url": "https://www.uniprot.org/uniprotkb/D3ZT71" } ], "pmid": "" }, { "name": "mitochondrion organization", "id": "GO:0007005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007005", "evidence": [ { "database": "UniProtKB", "id": "D3ZT71", "url": "https://www.uniprot.org/uniprotkb/D3ZT71" } ], "pmid": "" }, { "name": "canonical glycolysis", "id": "GO:0061621", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061621", "evidence": [ { "database": "UniProtKB", "id": "D3ZT71", "url": "https://www.uniprot.org/uniprotkb/D3ZT71" } ], "pmid": "" }, { "name": "mitophagy", "id": "GO:0000423", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000423", "evidence": [ { "database": "UniProtKB", "id": "D3ZT71", "url": "https://www.uniprot.org/uniprotkb/D3ZT71" } ], "pmid": "" }, { "name": "oxidative phosphorylation", "id": "GO:0006119", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006119", "evidence": [ { "database": "UniProtKB", "id": "D3ZT71", "url": "https://www.uniprot.org/uniprotkb/D3ZT71" } ], "pmid": "" }, { "name": "mitochondrial fission", "id": "GO:0000266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000266", "evidence": [ { "database": "UniProtKB", "id": "D3ZT71", "url": "https://www.uniprot.org/uniprotkb/D3ZT71" } ], "pmid": "" }, { "name": "left ventricular cardiac muscle tissue morphogenesis", "id": "GO:0003220", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003220", "evidence": [ { "database": "UniProtKB", "id": "D3ZT71", "url": "https://www.uniprot.org/uniprotkb/D3ZT71" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "D3ZT71-1", "start_pos": "348", "end_pos": "348", "site_lbl": "Thr348", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 348, "start_aa": "Thr", "end_pos": 348, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr348", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "D3ZT71-1" }, { "uniprot_canonical_ac": "D3ZTA9-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZTA9", "url": "https://www.uniprot.org/uniprotkb/D3ZTA9" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 390, "chemical_mass": 43339.0, "gene_names": "Hs3st3b1;Hs3st3b1;Hs3st3b", "protein_name": "Sulfotransferase", "disease": [], "biological_process": [ { "name": "protein sulfation", "id": "GO:0006477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006477", "evidence": [ { "database": "UniProtKB", "id": "D3ZTA9", "url": "https://www.uniprot.org/uniprotkb/D3ZTA9" } ], "pmid": "" }, { "name": "glycosaminoglycan biosynthetic process", "id": "GO:0006024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006024", "evidence": [ { "database": "UniProtKB", "id": "D3ZTA9", "url": "https://www.uniprot.org/uniprotkb/D3ZTA9" } ], "pmid": "" }, { "name": "branching involved in ureteric bud morphogenesis", "id": "GO:0001658", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001658", "evidence": [ { "database": "UniProtKB", "id": "D3ZTA9", "url": "https://www.uniprot.org/uniprotkb/D3ZTA9" } ], "pmid": "" }, { "name": "heparan sulfate proteoglycan biosynthetic process", "id": "GO:0015012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015012", "evidence": [ { "database": "UniProtKB", "id": "D3ZTA9", "url": "https://www.uniprot.org/uniprotkb/D3ZTA9" } ], "pmid": "" } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "D3ZTA9", "url": "https://www.uniprot.org/uniprotkb/D3ZTA9" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "D3ZTA9", "url": "https://www.uniprot.org/uniprotkb/D3ZTA9" } ], "pmid": "" } ], "molecular_function": [ { "name": "[heparan sulfate]-glucosamine 3-sulfotransferase activity", "id": "GO:0008467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008467", "evidence": [ { "database": "UniProtKB", "id": "D3ZTA9", "url": "https://www.uniprot.org/uniprotkb/D3ZTA9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZTA9-1" }, { "uniprot_canonical_ac": "D3ZTM2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZTM2", "url": "https://www.uniprot.org/uniprotkb/D3ZTM2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1021, "chemical_mass": 112421.0, "gene_names": "Ino80d;Ino80d;RGD1304808", "protein_name": "", "disease": [], "biological_process": [ { "name": "regulation of DNA strand elongation", "id": "GO:0060382", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060382", "evidence": [ { "database": "UniProtKB", "id": "D3ZTM2", "url": "https://www.uniprot.org/uniprotkb/D3ZTM2" } ], "pmid": "" }, { "name": "regulation of chromosome organization", "id": "GO:0033044", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033044", "evidence": [ { "database": "UniProtKB", "id": "D3ZTM2", "url": "https://www.uniprot.org/uniprotkb/D3ZTM2" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "D3ZTM2", "url": "https://www.uniprot.org/uniprotkb/D3ZTM2" } ], "pmid": "" }, { "name": "telomere maintenance", "id": "GO:0000723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000723", "evidence": [ { "database": "UniProtKB", "id": "D3ZTM2", "url": "https://www.uniprot.org/uniprotkb/D3ZTM2" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "D3ZTM2", "url": "https://www.uniprot.org/uniprotkb/D3ZTM2" } ], "pmid": "" }, { "name": "positive regulation of DNA repair", "id": "GO:0045739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045739", "evidence": [ { "database": "UniProtKB", "id": "D3ZTM2", "url": "https://www.uniprot.org/uniprotkb/D3ZTM2" } ], "pmid": "" }, { "name": "regulation of DNA replication", "id": "GO:0006275", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006275", "evidence": [ { "database": "UniProtKB", "id": "D3ZTM2", "url": "https://www.uniprot.org/uniprotkb/D3ZTM2" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "D3ZTM2", "url": "https://www.uniprot.org/uniprotkb/D3ZTM2" } ], "pmid": "" }, { "name": "regulation of embryonic development", "id": "GO:0045995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045995", "evidence": [ { "database": "UniProtKB", "id": "D3ZTM2", "url": "https://www.uniprot.org/uniprotkb/D3ZTM2" } ], "pmid": "" }, { "name": "regulation of DNA repair", "id": "GO:0006282", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006282", "evidence": [ { "database": "UniProtKB", "id": "D3ZTM2", "url": "https://www.uniprot.org/uniprotkb/D3ZTM2" } ], "pmid": "" }, { "name": "positive regulation of telomere maintenance in response to DNA damage", "id": "GO:1904507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904507", "evidence": [ { "database": "UniProtKB", "id": "D3ZTM2", "url": "https://www.uniprot.org/uniprotkb/D3ZTM2" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D3ZTM2", "url": "https://www.uniprot.org/uniprotkb/D3ZTM2" } ], "pmid": "" }, { "name": "Ino80 complex", "id": "GO:0031011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031011", "evidence": [ { "database": "UniProtKB", "id": "D3ZTM2", "url": "https://www.uniprot.org/uniprotkb/D3ZTM2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "D3ZTM2-1", "start_pos": "1019", "end_pos": "1019", "site_lbl": "Thr1019", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1019, "start_aa": "Thr", "end_pos": 1019, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1019", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "D3ZTM2-1", "start_pos": "199", "end_pos": "199", "site_lbl": "Thr199", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 199, "start_aa": "Thr", "end_pos": 199, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr199", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "D3ZTM2-1", "start_pos": "932", "end_pos": "932", "site_lbl": "Thr932", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 932, "start_aa": "Thr", "end_pos": 932, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr932", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "D3ZTM2-1" }, { "uniprot_canonical_ac": "D3ZTN0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 4126, "chemical_mass": 472074.0, "gene_names": "Prkdc;Prkdc", "protein_name": "DNA-dependent protein kinase catalytic subunit", "disease": [ { "disease_id": "DOID:0090013", "name": "severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-negative, Nk cell-positive", "description": "A severe combined immunodeficiency characterized by being T cell-negative, B cell-negative and natural killer cell-positive and that has_material_basis_in mutation in the RAG1 and RAG2 genes on chromosome 11p12.", "url": "https://disease-ontology.org/term/DOID:0090013", "evidence": [ { "id": "0090013", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0090013" } ], "weight": 0.0 }, { "disease_id": "DOID:0111961", "name": "immunodeficiency 26", "description": "A severe combined immunodeficiency characterized by virtually absent peripheral B and T cells but normal numbers of NK cells, complete block in B-cell differentiation, and a defect in slow repair of DNA double-strand breaks in fibroblasts, that has_material_basis_in homozygous or compound heterozygous mutation in the PRKDC gene on chromosome 8q11.21.", "url": "https://disease-ontology.org/term/DOID:0111961", "evidence": [ { "id": "0111961", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111961" } ], "weight": 0.0 }, { "disease_id": "DOID:627", "name": "severe combined immunodeficiency", "description": "A combined T cell and B cell immunodeficiency that is caused by a defect in infection-fighting immune cells resulting in individuals with non-functional immune systems.", "url": "https://disease-ontology.org/term/DOID:627", "evidence": [ { "id": "627", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:627" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nonhomologous end joining complex", "id": "GO:0070419", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070419", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "protein-DNA complex", "id": "GO:0032993", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032993", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "DNA-dependent protein kinase-DNA ligase 4 complex", "id": "GO:0005958", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005958", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "DNA-dependent protein kinase complex", "id": "GO:0070418", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070418", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "small-subunit processome", "id": "GO:0032040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032040", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" } ], "biological_process": [ { "name": "pro-B cell differentiation", "id": "GO:0002328", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002328", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "regulation of epithelial cell proliferation", "id": "GO:0050678", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050678", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "positive regulation of double-strand break repair via nonhomologous end joining", "id": "GO:2001034", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001034", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "T cell lineage commitment", "id": "GO:0002360", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002360", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "negative regulation of response to gamma radiation", "id": "GO:2001229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001229", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "protein phosphorylation", "id": "GO:0006468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006468", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "heart development", "id": "GO:0007507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007507", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "response to gamma radiation", "id": "GO:0010332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010332", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "cellular response to insulin stimulus", "id": "GO:0032869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032869", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "positive regulation of apoptotic process", "id": "GO:0043065", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043065", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "negative regulation of protein phosphorylation", "id": "GO:0001933", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001933", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "telomere maintenance", "id": "GO:0000723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000723", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "brain development", "id": "GO:0007420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "telomere capping", "id": "GO:0016233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016233", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "double-strand break repair", "id": "GO:0006302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006302", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "double-strand break repair via nonhomologous end joining", "id": "GO:0006303", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006303", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "intrinsic apoptotic signaling pathway in response to DNA damage", "id": "GO:0008630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008630", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "response to ionizing radiation", "id": "GO:0010212", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010212", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "spleen development", "id": "GO:0048536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048536", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "thymus development", "id": "GO:0048538", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048538", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "positive regulation of developmental growth", "id": "GO:0048639", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048639", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "regulation of hematopoietic stem cell differentiation", "id": "GO:1902036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902036", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "negative regulation of cellular senescence", "id": "GO:2000773", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000773", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "response to activity", "id": "GO:0014823", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014823", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "regulation of circadian rhythm", "id": "GO:0042752", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042752", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "small-subunit processome assembly", "id": "GO:0034462", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034462", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "somitogenesis", "id": "GO:0001756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001756", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "peptidyl-threonine phosphorylation", "id": "GO:0018107", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018107", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "positive regulation of erythrocyte differentiation", "id": "GO:0045648", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045648", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "positive regulation of translation", "id": "GO:0045727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045727", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "positive regulation of fibroblast proliferation", "id": "GO:0048146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048146", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "peptidyl-serine phosphorylation", "id": "GO:0018105", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018105", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "regulation of smooth muscle cell proliferation", "id": "GO:0048660", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048660", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "T cell differentiation in thymus", "id": "GO:0033077", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033077", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "activation of innate immune response", "id": "GO:0002218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002218", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "positive regulation of immune system process", "id": "GO:0002684", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002684", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "protein destabilization", "id": "GO:0031648", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031648", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "ectopic germ cell programmed cell death", "id": "GO:0035234", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035234", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "maturation of 5.8S rRNA", "id": "GO:0000460", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000460", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "positive regulation of lymphocyte differentiation", "id": "GO:0045621", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045621", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "V(D)J recombination", "id": "GO:0033151", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033151", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "B cell lineage commitment", "id": "GO:0002326", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002326", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "T cell receptor V(D)J recombination", "id": "GO:0033153", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033153", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "mitotic G1 DNA damage checkpoint signaling", "id": "GO:0031571", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031571", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "lymphocyte differentiation", "id": "GO:0030098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030098", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "immunoglobulin V(D)J recombination", "id": "GO:0033152", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033152", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "negative regulation of immunoglobulin production", "id": "GO:0002638", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002638", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "positive regulation of platelet formation", "id": "GO:1905221", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905221", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "negative regulation of cGAS/STING signaling pathway", "id": "GO:0160049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160049", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "positive regulation of biosynthetic process", "id": "GO:0009891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009891", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "enzyme binding", "id": "GO:0019899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019899", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "protein domain specific binding", "id": "GO:0019904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019904", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "double-stranded DNA binding", "id": "GO:0003690", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003690", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "RNA polymerase II-specific DNA-binding transcription factor binding", "id": "GO:0061629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061629", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "DNA-dependent protein kinase activity", "id": "GO:0004677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004677", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "U3 snoRNA binding", "id": "GO:0034511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034511", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" }, { "name": "histone H2AXS139 kinase activity", "id": "GO:0035979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035979", "evidence": [ { "database": "UniProtKB", "id": "D3ZTN0", "url": "https://www.uniprot.org/uniprotkb/D3ZTN0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZTN0-1" }, { "uniprot_canonical_ac": "D3ZTX2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZTX2", "url": "https://www.uniprot.org/uniprotkb/D3ZTX2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 353, "chemical_mass": 36178.0, "gene_names": "Nkx2-4;Nkx2-4", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D3ZTX2", "url": "https://www.uniprot.org/uniprotkb/D3ZTX2" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "D3ZTX2", "url": "https://www.uniprot.org/uniprotkb/D3ZTX2" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "D3ZTX2", "url": "https://www.uniprot.org/uniprotkb/D3ZTX2" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "D3ZTX2", "url": "https://www.uniprot.org/uniprotkb/D3ZTX2" } ], "pmid": "" }, { "name": "animal organ development", "id": "GO:0048513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048513", "evidence": [ { "database": "UniProtKB", "id": "D3ZTX2", "url": "https://www.uniprot.org/uniprotkb/D3ZTX2" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "D3ZTX2", "url": "https://www.uniprot.org/uniprotkb/D3ZTX2" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "D3ZTX2", "url": "https://www.uniprot.org/uniprotkb/D3ZTX2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "D3ZTX2-1", "start_pos": "294", "end_pos": "294", "site_lbl": "Thr294", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 294, "start_aa": "Thr", "end_pos": 294, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr294", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "D3ZTX2-1", "start_pos": "306", "end_pos": "306", "site_lbl": "Thr306", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 306, "start_aa": "Thr", "end_pos": 306, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr306", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "D3ZTX2-1" }, { "uniprot_canonical_ac": "D3ZU40-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZU40", "url": "https://www.uniprot.org/uniprotkb/D3ZU40" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 496, "chemical_mass": 55628.0, "gene_names": "Slc38a12;RGD1307953;Slc38a12;Tmem104", "protein_name": "Putative sodium-coupled neutral amino acid transporter 12", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "D3ZU40", "url": "https://www.uniprot.org/uniprotkb/D3ZU40" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZU40-1" }, { "uniprot_canonical_ac": "D3ZUX6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZUX6", "url": "https://www.uniprot.org/uniprotkb/D3ZUX6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 341, "chemical_mass": 36432.0, "gene_names": "Ms4a18;LOC100359485", "protein_name": "", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "D3ZUX6", "url": "https://www.uniprot.org/uniprotkb/D3ZUX6" } ], "pmid": "" } ], "biological_process": [ { "name": "cell surface receptor signaling pathway", "id": "GO:0007166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007166", "evidence": [ { "database": "UniProtKB", "id": "D3ZUX6", "url": "https://www.uniprot.org/uniprotkb/D3ZUX6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "D3ZUX6-1", "start_pos": "124", "end_pos": "124", "site_lbl": "Thr124", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 124, "start_aa": "Thr", "end_pos": 124, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr124", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "D3ZUX6-1", "start_pos": "243", "end_pos": "243", "site_lbl": "Thr243", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 243, "start_aa": "Thr", "end_pos": 243, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr243", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "D3ZUX6-1" }, { "uniprot_canonical_ac": "D3ZVG6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZVG6", "url": "https://www.uniprot.org/uniprotkb/D3ZVG6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 321, "chemical_mass": 34489.0, "gene_names": "Klf14;Klf14", "protein_name": "", "disease": [], "biological_process": [ { "name": "cellular response to endothelin", "id": "GO:1990859", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990859", "evidence": [ { "database": "UniProtKB", "id": "D3ZVG6", "url": "https://www.uniprot.org/uniprotkb/D3ZVG6" } ], "pmid": "" }, { "name": "positive regulation of sphingolipid mediated signaling pathway", "id": "GO:1902070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902070", "evidence": [ { "database": "UniProtKB", "id": "D3ZVG6", "url": "https://www.uniprot.org/uniprotkb/D3ZVG6" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "D3ZVG6", "url": "https://www.uniprot.org/uniprotkb/D3ZVG6" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "D3ZVG6", "url": "https://www.uniprot.org/uniprotkb/D3ZVG6" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "D3ZVG6", "url": "https://www.uniprot.org/uniprotkb/D3ZVG6" } ], "pmid": "" } ], "molecular_function": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "D3ZVG6", "url": "https://www.uniprot.org/uniprotkb/D3ZVG6" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "D3ZVG6", "url": "https://www.uniprot.org/uniprotkb/D3ZVG6" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "D3ZVG6", "url": "https://www.uniprot.org/uniprotkb/D3ZVG6" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "D3ZVG6", "url": "https://www.uniprot.org/uniprotkb/D3ZVG6" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "D3ZVG6", "url": "https://www.uniprot.org/uniprotkb/D3ZVG6" } ], "pmid": "" }, { "name": "sequence-specific double-stranded DNA binding", "id": "GO:1990837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990837", "evidence": [ { "database": "UniProtKB", "id": "D3ZVG6", "url": "https://www.uniprot.org/uniprotkb/D3ZVG6" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D3ZVG6", "url": "https://www.uniprot.org/uniprotkb/D3ZVG6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "D3ZVG6-1", "start_pos": "189", "end_pos": "189", "site_lbl": "Thr189", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 189, "start_aa": "Thr", "end_pos": 189, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr189", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "D3ZVG6-1" }, { "uniprot_canonical_ac": "D3ZVT0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZVT0", "url": "https://www.uniprot.org/uniprotkb/D3ZVT0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 683, "chemical_mass": 78851.0, "gene_names": "ZNF418;Zfp418", "protein_name": "Zinc finger protein 418", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D3ZVT0", "url": "https://www.uniprot.org/uniprotkb/D3ZVT0" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "D3ZVT0", "url": "https://www.uniprot.org/uniprotkb/D3ZVT0" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "D3ZVT0", "url": "https://www.uniprot.org/uniprotkb/D3ZVT0" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "D3ZVT0", "url": "https://www.uniprot.org/uniprotkb/D3ZVT0" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity", "id": "GO:0001216", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001216", "evidence": [ { "database": "UniProtKB", "id": "D3ZVT0", "url": "https://www.uniprot.org/uniprotkb/D3ZVT0" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity", "id": "GO:0001217", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001217", "evidence": [ { "database": "UniProtKB", "id": "D3ZVT0", "url": "https://www.uniprot.org/uniprotkb/D3ZVT0" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "D3ZVT0", "url": "https://www.uniprot.org/uniprotkb/D3ZVT0" } ], "pmid": "" }, { "name": "fibroblast proliferation", "id": "GO:0048144", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048144", "evidence": [ { "database": "UniProtKB", "id": "D3ZVT0", "url": "https://www.uniprot.org/uniprotkb/D3ZVT0" } ], "pmid": "" }, { "name": "regulation of proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0032434", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032434", "evidence": [ { "database": "UniProtKB", "id": "D3ZVT0", "url": "https://www.uniprot.org/uniprotkb/D3ZVT0" } ], "pmid": "" }, { "name": "fibroblast activation", "id": "GO:0072537", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072537", "evidence": [ { "database": "UniProtKB", "id": "D3ZVT0", "url": "https://www.uniprot.org/uniprotkb/D3ZVT0" } ], "pmid": "" }, { "name": "microautophagy", "id": "GO:0016237", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016237", "evidence": [ { "database": "UniProtKB", "id": "D3ZVT0", "url": "https://www.uniprot.org/uniprotkb/D3ZVT0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZVT0-1" }, { "uniprot_canonical_ac": "D3ZW02-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZW02", "url": "https://www.uniprot.org/uniprotkb/D3ZW02" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1351, "chemical_mass": 149164.0, "gene_names": "Disp3;Disp3;Ptchd2;RGD1305820", "protein_name": "Protein dispatched homolog 3", "disease": [], "biological_process": [ { "name": "positive regulation of lipid metabolic process", "id": "GO:0045834", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045834", "evidence": [ { "database": "UniProtKB", "id": "D3ZW02", "url": "https://www.uniprot.org/uniprotkb/D3ZW02" } ], "pmid": "" }, { "name": "cholesterol metabolic process", "id": "GO:0008203", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008203", "evidence": [ { "database": "UniProtKB", "id": "D3ZW02", "url": "https://www.uniprot.org/uniprotkb/D3ZW02" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "D3ZW02", "url": "https://www.uniprot.org/uniprotkb/D3ZW02" } ], "pmid": "" }, { "name": "negative regulation of neuron differentiation", "id": "GO:0045665", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045665", "evidence": [ { "database": "UniProtKB", "id": "D3ZW02", "url": "https://www.uniprot.org/uniprotkb/D3ZW02" } ], "pmid": "" }, { "name": "positive regulation of neural precursor cell proliferation", "id": "GO:2000179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000179", "evidence": [ { "database": "UniProtKB", "id": "D3ZW02", "url": "https://www.uniprot.org/uniprotkb/D3ZW02" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "D3ZW02", "url": "https://www.uniprot.org/uniprotkb/D3ZW02" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "D3ZW02", "url": "https://www.uniprot.org/uniprotkb/D3ZW02" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "D3ZW02", "url": "https://www.uniprot.org/uniprotkb/D3ZW02" } ], "pmid": "" }, { "name": "cytoplasmic vesicle membrane", "id": "GO:0030659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030659", "evidence": [ { "database": "UniProtKB", "id": "D3ZW02", "url": "https://www.uniprot.org/uniprotkb/D3ZW02" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "D3ZW02-1", "start_pos": "659", "end_pos": "659", "site_lbl": "Thr659", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 659, "start_aa": "Thr", "end_pos": 659, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr659", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "D3ZW02-1", "start_pos": "925", "end_pos": "925", "site_lbl": "Thr925", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 925, "start_aa": "Thr", "end_pos": 925, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr925", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "D3ZW02-1" }, { "uniprot_canonical_ac": "D3ZW33-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZW33", "url": "https://www.uniprot.org/uniprotkb/D3ZW33" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 839, "chemical_mass": 91944.0, "gene_names": "Bach2;Bach2;RGD1562865", "protein_name": "", "disease": [ { "disease_id": "DOID:0111954", "name": "immunodeficiency 60", "description": "A combined T cell and B cell immunodeficiency characterized by variably decreased immunoglobulin production, decreased T-regulatory cells, overall impaired lymphocyte maturation, inflammatory bowel disease and recurrent sinopulmonary infections that has_material_basis_in heterozygous mutation in the BACH2 gene on chromosome 6q15.", "url": "https://disease-ontology.org/term/DOID:0111954", "evidence": [ { "id": "0111954", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111954" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D3ZW33", "url": "https://www.uniprot.org/uniprotkb/D3ZW33" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "D3ZW33", "url": "https://www.uniprot.org/uniprotkb/D3ZW33" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "D3ZW33", "url": "https://www.uniprot.org/uniprotkb/D3ZW33" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulator complex", "id": "GO:0090575", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090575", "evidence": [ { "database": "UniProtKB", "id": "D3ZW33", "url": "https://www.uniprot.org/uniprotkb/D3ZW33" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "D3ZW33", "url": "https://www.uniprot.org/uniprotkb/D3ZW33" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "D3ZW33", "url": "https://www.uniprot.org/uniprotkb/D3ZW33" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "D3ZW33", "url": "https://www.uniprot.org/uniprotkb/D3ZW33" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "D3ZW33", "url": "https://www.uniprot.org/uniprotkb/D3ZW33" } ], "pmid": "" }, { "name": "import into nucleus", "id": "GO:0051170", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051170", "evidence": [ { "database": "UniProtKB", "id": "D3ZW33", "url": "https://www.uniprot.org/uniprotkb/D3ZW33" } ], "pmid": "" }, { "name": "primary adaptive immune response involving T cells and B cells", "id": "GO:0090721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090721", "evidence": [ { "database": "UniProtKB", "id": "D3ZW33", "url": "https://www.uniprot.org/uniprotkb/D3ZW33" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "D3ZW33", "url": "https://www.uniprot.org/uniprotkb/D3ZW33" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "D3ZW33", "url": "https://www.uniprot.org/uniprotkb/D3ZW33" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "D3ZW33", "url": "https://www.uniprot.org/uniprotkb/D3ZW33" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "D3ZW33", "url": "https://www.uniprot.org/uniprotkb/D3ZW33" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "D3ZW33", "url": "https://www.uniprot.org/uniprotkb/D3ZW33" } ], "pmid": "" }, { "name": "sequence-specific double-stranded DNA binding", "id": "GO:1990837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990837", "evidence": [ { "database": "UniProtKB", "id": "D3ZW33", "url": "https://www.uniprot.org/uniprotkb/D3ZW33" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZW33-1" }, { "uniprot_canonical_ac": "D3ZW58-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZW58", "url": "https://www.uniprot.org/uniprotkb/D3ZW58" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 435, "chemical_mass": 49414.0, "gene_names": "Golm2;Casc4;Golm2;RGD1305985", "protein_name": "Protein GOLM2", "disease": [], "cellular_component": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "D3ZW58", "url": "https://www.uniprot.org/uniprotkb/D3ZW58" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "D3ZW58", "url": "https://www.uniprot.org/uniprotkb/D3ZW58" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZW58-1" }, { "uniprot_canonical_ac": "D3ZW79-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZW79", "url": "https://www.uniprot.org/uniprotkb/D3ZW79" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 696, "chemical_mass": 74135.0, "gene_names": "Ebf4;Ebf4", "protein_name": "Transcription factor COE4", "disease": [], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "D3ZW79", "url": "https://www.uniprot.org/uniprotkb/D3ZW79" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "D3ZW79", "url": "https://www.uniprot.org/uniprotkb/D3ZW79" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "D3ZW79", "url": "https://www.uniprot.org/uniprotkb/D3ZW79" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "D3ZW79", "url": "https://www.uniprot.org/uniprotkb/D3ZW79" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "D3ZW79", "url": "https://www.uniprot.org/uniprotkb/D3ZW79" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "D3ZW79", "url": "https://www.uniprot.org/uniprotkb/D3ZW79" } ], "pmid": "" }, { "name": "DNA-binding transcription factor binding", "id": "GO:0140297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140297", "evidence": [ { "database": "UniProtKB", "id": "D3ZW79", "url": "https://www.uniprot.org/uniprotkb/D3ZW79" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "D3ZW79", "url": "https://www.uniprot.org/uniprotkb/D3ZW79" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D3ZW79", "url": "https://www.uniprot.org/uniprotkb/D3ZW79" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "D3ZW79", "url": "https://www.uniprot.org/uniprotkb/D3ZW79" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "D3ZW79", "url": "https://www.uniprot.org/uniprotkb/D3ZW79" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "D3ZW79", "url": "https://www.uniprot.org/uniprotkb/D3ZW79" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "D3ZW79", "url": "https://www.uniprot.org/uniprotkb/D3ZW79" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "D3ZW79", "url": "https://www.uniprot.org/uniprotkb/D3ZW79" } ], "pmid": "" }, { "name": "T cell apoptotic process", "id": "GO:0070231", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070231", "evidence": [ { "database": "UniProtKB", "id": "D3ZW79", "url": "https://www.uniprot.org/uniprotkb/D3ZW79" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZW79-1" }, { "uniprot_canonical_ac": "D3ZW88-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZW88", "url": "https://www.uniprot.org/uniprotkb/D3ZW88" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1555, "chemical_mass": 169924.0, "gene_names": "Frmpd1", "protein_name": "FERM and PDZ domain-containing protein 1", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "D3ZW88", "url": "https://www.uniprot.org/uniprotkb/D3ZW88" } ], "pmid": "" }, { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "D3ZW88", "url": "https://www.uniprot.org/uniprotkb/D3ZW88" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "D3ZW88", "url": "https://www.uniprot.org/uniprotkb/D3ZW88" } ], "pmid": "" } ], "biological_process": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "D3ZW88", "url": "https://www.uniprot.org/uniprotkb/D3ZW88" } ], "pmid": "" }, { "name": "response to light intensity", "id": "GO:0009642", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009642", "evidence": [ { "database": "UniProtKB", "id": "D3ZW88", "url": "https://www.uniprot.org/uniprotkb/D3ZW88" } ], "pmid": "" }, { "name": "establishment of protein localization to membrane", "id": "GO:0090150", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090150", "evidence": [ { "database": "UniProtKB", "id": "D3ZW88", "url": "https://www.uniprot.org/uniprotkb/D3ZW88" } ], "pmid": "" }, { "name": "regulation of G protein-coupled receptor signaling pathway", "id": "GO:0008277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008277", "evidence": [ { "database": "UniProtKB", "id": "D3ZW88", "url": "https://www.uniprot.org/uniprotkb/D3ZW88" } ], "pmid": "" }, { "name": "light adaption", "id": "GO:0036367", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036367", "evidence": [ { "database": "UniProtKB", "id": "D3ZW88", "url": "https://www.uniprot.org/uniprotkb/D3ZW88" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "D3ZW88-1", "start_pos": "571", "end_pos": "571", "site_lbl": "Thr571", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 571, "start_aa": "Thr", "end_pos": 571, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr571", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "D3ZW88-1", "start_pos": "85", "end_pos": "85", "site_lbl": "Thr85", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 85, "start_aa": "Thr", "end_pos": 85, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr85", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "D3ZW88-1", "start_pos": "889", "end_pos": "889", "site_lbl": "Thr889", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 889, "start_aa": "Thr", "end_pos": 889, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr889", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "D3ZW88-1" }, { "uniprot_canonical_ac": "D3ZWI8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZWI8", "url": "https://www.uniprot.org/uniprotkb/D3ZWI8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 230, "chemical_mass": 25270.0, "gene_names": "Dnajb8;Dnajb8;RGD1561981", "protein_name": "", "disease": [ { "disease_id": "DOID:0110305", "name": "autosomal dominant limb-girdle muscular dystrophy type 1", "description": "An autosomal dominant limb-girdle muscular dystrophy that has_material_basis_in heterozygous mutation in the DNAJB6 gene on chromosome 7q36.", "url": "https://disease-ontology.org/term/DOID:0110305", "evidence": [ { "id": "0110305", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110305" } ], "weight": 0.0 } ], "biological_process": [ { "name": "negative regulation of inclusion body assembly", "id": "GO:0090084", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090084", "evidence": [ { "database": "UniProtKB", "id": "D3ZWI8", "url": "https://www.uniprot.org/uniprotkb/D3ZWI8" } ], "pmid": "" }, { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "D3ZWI8", "url": "https://www.uniprot.org/uniprotkb/D3ZWI8" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D3ZWI8", "url": "https://www.uniprot.org/uniprotkb/D3ZWI8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "D3ZWI8", "url": "https://www.uniprot.org/uniprotkb/D3ZWI8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "D3ZWI8", "url": "https://www.uniprot.org/uniprotkb/D3ZWI8" } ], "pmid": "" } ], "molecular_function": [ { "name": "unfolded protein binding", "id": "GO:0051082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051082", "evidence": [ { "database": "UniProtKB", "id": "D3ZWI8", "url": "https://www.uniprot.org/uniprotkb/D3ZWI8" } ], "pmid": "" }, { "name": "protein-folding chaperone binding", "id": "GO:0051087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051087", "evidence": [ { "database": "UniProtKB", "id": "D3ZWI8", "url": "https://www.uniprot.org/uniprotkb/D3ZWI8" } ], "pmid": "" }, { "name": "Hsp70 protein binding", "id": "GO:0030544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030544", "evidence": [ { "database": "UniProtKB", "id": "D3ZWI8", "url": "https://www.uniprot.org/uniprotkb/D3ZWI8" } ], "pmid": "" }, { "name": "protein folding chaperone", "id": "GO:0044183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044183", "evidence": [ { "database": "UniProtKB", "id": "D3ZWI8", "url": "https://www.uniprot.org/uniprotkb/D3ZWI8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZWI8-1" }, { "uniprot_canonical_ac": "D3ZWR3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZWR3", "url": "https://www.uniprot.org/uniprotkb/D3ZWR3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 627, "chemical_mass": 69299.0, "gene_names": "Asnsd1;Asdurf", "protein_name": "Asparagine synthetase domain-containing protein 1", "disease": [ { "disease_id": "DOID:423", "name": "myopathy", "description": "A muscular disease in which the muscle fibers do not function resulting in muscular weakness.", "url": "https://disease-ontology.org/term/DOID:423", "evidence": [ { "id": "423", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:423" } ], "weight": 0.0 } ], "biological_process": [ { "name": "skeletal muscle organ development", "id": "GO:0060538", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060538", "evidence": [ { "database": "UniProtKB", "id": "D3ZWR3", "url": "https://www.uniprot.org/uniprotkb/D3ZWR3" } ], "pmid": "" }, { "name": "adipose tissue development", "id": "GO:0060612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060612", "evidence": [ { "database": "UniProtKB", "id": "D3ZWR3", "url": "https://www.uniprot.org/uniprotkb/D3ZWR3" } ], "pmid": "" }, { "name": "muscle organ development", "id": "GO:0007517", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007517", "evidence": [ { "database": "UniProtKB", "id": "D3ZWR3", "url": "https://www.uniprot.org/uniprotkb/D3ZWR3" } ], "pmid": "" }, { "name": "L-asparagine biosynthetic process", "id": "GO:0070981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070981", "evidence": [ { "database": "UniProtKB", "id": "D3ZWR3", "url": "https://www.uniprot.org/uniprotkb/D3ZWR3" } ], "pmid": "" }, { "name": "transdifferentiation", "id": "GO:0060290", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060290", "evidence": [ { "database": "UniProtKB", "id": "D3ZWR3", "url": "https://www.uniprot.org/uniprotkb/D3ZWR3" } ], "pmid": "" }, { "name": "skeletal muscle tissue development", "id": "GO:0007519", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007519", "evidence": [ { "database": "UniProtKB", "id": "D3ZWR3", "url": "https://www.uniprot.org/uniprotkb/D3ZWR3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZWR3-1" }, { "uniprot_canonical_ac": "D3ZWS2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZWS2", "url": "https://www.uniprot.org/uniprotkb/D3ZWS2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 145, "chemical_mass": 15488.0, "gene_names": "C1h19orf12;C1h19orf12;LOC690000", "protein_name": "", "disease": [ { "disease_id": "DOID:0110738", "name": "neurodegeneration with brain iron accumulation 4", "description": "A neurodegeneration with brain iron accumulation that has_material_basis_in autosomal recessive inheritance of mutation in the C19orf12 gene on chromosome 19q12.", "url": "https://disease-ontology.org/term/DOID:0110738", "evidence": [ { "id": "0110738", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110738" } ], "weight": 0.0 }, { "disease_id": "DOID:0110795", "name": "hereditary spastic paraplegia 43", "description": "A hereditary spastic paraplegia that has_material_basis_in mutation in the C19ORF12 gene on chromosome 19q12.", "url": "https://disease-ontology.org/term/DOID:0110795", "evidence": [ { "id": "0110795", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110795" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "D3ZWS2", "url": "https://www.uniprot.org/uniprotkb/D3ZWS2" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "D3ZWS2", "url": "https://www.uniprot.org/uniprotkb/D3ZWS2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "D3ZWS2", "url": "https://www.uniprot.org/uniprotkb/D3ZWS2" } ], "pmid": "" }, { "name": "mitochondrial membrane", "id": "GO:0031966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031966", "evidence": [ { "database": "UniProtKB", "id": "D3ZWS2", "url": "https://www.uniprot.org/uniprotkb/D3ZWS2" } ], "pmid": "" } ], "biological_process": [ { "name": "response to oxidative stress", "id": "GO:0006979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006979", "evidence": [ { "database": "UniProtKB", "id": "D3ZWS2", "url": "https://www.uniprot.org/uniprotkb/D3ZWS2" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "D3ZWS2", "url": "https://www.uniprot.org/uniprotkb/D3ZWS2" } ], "pmid": "" }, { "name": "autophagy", "id": "GO:0006914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006914", "evidence": [ { "database": "UniProtKB", "id": "D3ZWS2", "url": "https://www.uniprot.org/uniprotkb/D3ZWS2" } ], "pmid": "" }, { "name": "mitochondrial calcium ion homeostasis", "id": "GO:0051560", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051560", "evidence": [ { "database": "UniProtKB", "id": "D3ZWS2", "url": "https://www.uniprot.org/uniprotkb/D3ZWS2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "D3ZWS2-1", "start_pos": "60", "end_pos": "60", "site_lbl": "Thr60", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 60, "start_aa": "Thr", "end_pos": 60, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr60", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "D3ZWS2-1" }, { "uniprot_canonical_ac": "D3ZWX4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZWX4", "url": "https://www.uniprot.org/uniprotkb/D3ZWX4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 771, "chemical_mass": 84431.0, "gene_names": "Nckipsd", "protein_name": "", "disease": [], "cellular_component": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "D3ZWX4", "url": "https://www.uniprot.org/uniprotkb/D3ZWX4" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "D3ZWX4", "url": "https://www.uniprot.org/uniprotkb/D3ZWX4" } ], "pmid": "" }, { "name": "postsynapse", "id": "GO:0098794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098794", "evidence": [ { "database": "UniProtKB", "id": "D3ZWX4", "url": "https://www.uniprot.org/uniprotkb/D3ZWX4" } ], "pmid": "" }, { "name": "COP9 signalosome", "id": "GO:0008180", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008180", "evidence": [ { "database": "UniProtKB", "id": "D3ZWX4", "url": "https://www.uniprot.org/uniprotkb/D3ZWX4" } ], "pmid": "" } ], "biological_process": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "D3ZWX4", "url": "https://www.uniprot.org/uniprotkb/D3ZWX4" } ], "pmid": "" }, { "name": "positive regulation of neuron projection development", "id": "GO:0010976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010976", "evidence": [ { "database": "UniProtKB", "id": "D3ZWX4", "url": "https://www.uniprot.org/uniprotkb/D3ZWX4" } ], "pmid": "" }, { "name": "regulation of postsynapse assembly", "id": "GO:0150052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0150052", "evidence": [ { "database": "UniProtKB", "id": "D3ZWX4", "url": "https://www.uniprot.org/uniprotkb/D3ZWX4" } ], "pmid": "" } ], "molecular_function": [ { "name": "Arp2/3 complex binding", "id": "GO:0071933", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071933", "evidence": [ { "database": "UniProtKB", "id": "D3ZWX4", "url": "https://www.uniprot.org/uniprotkb/D3ZWX4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "D3ZWX4-1", "start_pos": "231", "end_pos": "231", "site_lbl": "Thr231", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" }, { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "reported site T165 is on non-canonical isoform A0ABK0LRT3-1 which maps to canonical isoform site D3ZWX4-1:231", "icn3d_view": {}, "start_pos": 231, "start_aa": "Thr", "end_pos": 231, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr231", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "D3ZWX4-1", "start_pos": "292", "end_pos": "292", "site_lbl": "Thr292", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" }, { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "reported site T226 is on non-canonical isoform A0ABK0LRT3-1 which maps to canonical isoform site D3ZWX4-1:292", "icn3d_view": {}, "start_pos": 292, "start_aa": "Thr", "end_pos": 292, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr292", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "D3ZWX4-1" }, { "uniprot_canonical_ac": "D3ZX09-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZX09", "url": "https://www.uniprot.org/uniprotkb/D3ZX09" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 439, "chemical_mass": 47558.0, "gene_names": "Astl;Astl;RGD1562279", "protein_name": "Metalloendopeptidase", "disease": [], "molecular_function": [ { "name": "metalloendopeptidase activity", "id": "GO:0004222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004222", "evidence": [ { "database": "UniProtKB", "id": "D3ZX09", "url": "https://www.uniprot.org/uniprotkb/D3ZX09" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "D3ZX09", "url": "https://www.uniprot.org/uniprotkb/D3ZX09" } ], "pmid": "" }, { "name": "peptidase activity", "id": "GO:0008233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008233", "evidence": [ { "database": "UniProtKB", "id": "D3ZX09", "url": "https://www.uniprot.org/uniprotkb/D3ZX09" } ], "pmid": "" }, { "name": "aspartic-type peptidase activity", "id": "GO:0070001", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070001", "evidence": [ { "database": "UniProtKB", "id": "D3ZX09", "url": "https://www.uniprot.org/uniprotkb/D3ZX09" } ], "pmid": "" }, { "name": "glutamic-type peptidase activity", "id": "GO:0070002", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070002", "evidence": [ { "database": "UniProtKB", "id": "D3ZX09", "url": "https://www.uniprot.org/uniprotkb/D3ZX09" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "D3ZX09", "url": "https://www.uniprot.org/uniprotkb/D3ZX09" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "D3ZX09", "url": "https://www.uniprot.org/uniprotkb/D3ZX09" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "D3ZX09", "url": "https://www.uniprot.org/uniprotkb/D3ZX09" } ], "pmid": "" }, { "name": "cortical granule", "id": "GO:0060473", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060473", "evidence": [ { "database": "UniProtKB", "id": "D3ZX09", "url": "https://www.uniprot.org/uniprotkb/D3ZX09" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "D3ZX09", "url": "https://www.uniprot.org/uniprotkb/D3ZX09" } ], "pmid": "" }, { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "D3ZX09", "url": "https://www.uniprot.org/uniprotkb/D3ZX09" } ], "pmid": "" }, { "name": "fertilization", "id": "GO:0009566", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009566", "evidence": [ { "database": "UniProtKB", "id": "D3ZX09", "url": "https://www.uniprot.org/uniprotkb/D3ZX09" } ], "pmid": "" }, { "name": "positive regulation of protein processing", "id": "GO:0010954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010954", "evidence": [ { "database": "UniProtKB", "id": "D3ZX09", "url": "https://www.uniprot.org/uniprotkb/D3ZX09" } ], "pmid": "" }, { "name": "prevention of polyspermy", "id": "GO:0060468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060468", "evidence": [ { "database": "UniProtKB", "id": "D3ZX09", "url": "https://www.uniprot.org/uniprotkb/D3ZX09" } ], "pmid": "" }, { "name": "negative regulation of binding of sperm to zona pellucida", "id": "GO:2000360", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000360", "evidence": [ { "database": "UniProtKB", "id": "D3ZX09", "url": "https://www.uniprot.org/uniprotkb/D3ZX09" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "D3ZX09-1", "start_pos": "306", "end_pos": "306", "site_lbl": "Thr306", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 306, "start_aa": "Thr", "end_pos": 306, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr306", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "D3ZX09-1" }, { "uniprot_canonical_ac": "D3ZXT7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZXT7", "url": "https://www.uniprot.org/uniprotkb/D3ZXT7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 379, "chemical_mass": 41819.0, "gene_names": "Timd4", "protein_name": "", "disease": [], "molecular_function": [ { "name": "phosphatidylserine binding", "id": "GO:0001786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001786", "evidence": [ { "database": "UniProtKB", "id": "D3ZXT7", "url": "https://www.uniprot.org/uniprotkb/D3ZXT7" } ], "pmid": "" } ], "biological_process": [ { "name": "apoptotic cell clearance", "id": "GO:0043277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043277", "evidence": [ { "database": "UniProtKB", "id": "D3ZXT7", "url": "https://www.uniprot.org/uniprotkb/D3ZXT7" } ], "pmid": "" }, { "name": "cytoskeletal rearrangement involved in phagocytosis, engulfment", "id": "GO:0060097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060097", "evidence": [ { "database": "UniProtKB", "id": "D3ZXT7", "url": "https://www.uniprot.org/uniprotkb/D3ZXT7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZXT7-1" }, { "uniprot_canonical_ac": "D3ZXY0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZXY0", "url": "https://www.uniprot.org/uniprotkb/D3ZXY0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 309, "chemical_mass": 34366.0, "gene_names": "Or5ak4;Olr439;Or5ak22", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "D3ZXY0", "url": "https://www.uniprot.org/uniprotkb/D3ZXY0" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "D3ZXY0", "url": "https://www.uniprot.org/uniprotkb/D3ZXY0" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "D3ZXY0", "url": "https://www.uniprot.org/uniprotkb/D3ZXY0" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "D3ZXY0", "url": "https://www.uniprot.org/uniprotkb/D3ZXY0" } ], "pmid": "" } ], "biological_process": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "D3ZXY0", "url": "https://www.uniprot.org/uniprotkb/D3ZXY0" } ], "pmid": "" }, { "name": "sensory perception of smell", "id": "GO:0007608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007608", "evidence": [ { "database": "UniProtKB", "id": "D3ZXY0", "url": "https://www.uniprot.org/uniprotkb/D3ZXY0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZXY0-1" }, { "uniprot_canonical_ac": "D3ZY52-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZY52", "url": "https://www.uniprot.org/uniprotkb/D3ZY52" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 708, "chemical_mass": 74839.0, "gene_names": "Eomes;Eomes", "protein_name": "", "disease": [], "biological_process": [ { "name": "astrocyte differentiation", "id": "GO:0048708", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048708", "evidence": [ { "database": "UniProtKB", "id": "D3ZY52", "url": "https://www.uniprot.org/uniprotkb/D3ZY52" } ], "pmid": "" }, { "name": "endodermal cell fate specification", "id": "GO:0001714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001714", "evidence": [ { "database": "UniProtKB", "id": "D3ZY52", "url": "https://www.uniprot.org/uniprotkb/D3ZY52" } ], "pmid": "" }, { "name": "CD8-positive, alpha-beta T cell differentiation involved in immune response", "id": "GO:0002302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002302", "evidence": [ { "database": "UniProtKB", "id": "D3ZY52", "url": "https://www.uniprot.org/uniprotkb/D3ZY52" } ], "pmid": "" }, { "name": "cell differentiation involved in embryonic placenta development", "id": "GO:0060706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060706", "evidence": [ { "database": "UniProtKB", "id": "D3ZY52", "url": "https://www.uniprot.org/uniprotkb/D3ZY52" } ], "pmid": "" }, { "name": "mesodermal to mesenchymal transition involved in gastrulation", "id": "GO:0060809", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060809", "evidence": [ { "database": "UniProtKB", "id": "D3ZY52", "url": "https://www.uniprot.org/uniprotkb/D3ZY52" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "D3ZY52", "url": "https://www.uniprot.org/uniprotkb/D3ZY52" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "D3ZY52", "url": "https://www.uniprot.org/uniprotkb/D3ZY52" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "D3ZY52", "url": "https://www.uniprot.org/uniprotkb/D3ZY52" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "D3ZY52", "url": "https://www.uniprot.org/uniprotkb/D3ZY52" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "D3ZY52", "url": "https://www.uniprot.org/uniprotkb/D3ZY52" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "D3ZY52", "url": "https://www.uniprot.org/uniprotkb/D3ZY52" } ], "pmid": "" }, { "name": "neuron migration", "id": "GO:0001764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001764", "evidence": [ { "database": "UniProtKB", "id": "D3ZY52", "url": "https://www.uniprot.org/uniprotkb/D3ZY52" } ], "pmid": "" }, { "name": "cerebral cortex development", "id": "GO:0021987", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021987", "evidence": [ { "database": "UniProtKB", "id": "D3ZY52", "url": "https://www.uniprot.org/uniprotkb/D3ZY52" } ], "pmid": "" }, { "name": "trophectodermal cell differentiation", "id": "GO:0001829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001829", "evidence": [ { "database": "UniProtKB", "id": "D3ZY52", "url": "https://www.uniprot.org/uniprotkb/D3ZY52" } ], "pmid": "" }, { "name": "brain development", "id": "GO:0007420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420", "evidence": [ { "database": "UniProtKB", "id": "D3ZY52", "url": "https://www.uniprot.org/uniprotkb/D3ZY52" } ], "pmid": "" }, { "name": "neuron differentiation", "id": "GO:0030182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030182", "evidence": [ { "database": "UniProtKB", "id": "D3ZY52", "url": "https://www.uniprot.org/uniprotkb/D3ZY52" } ], "pmid": "" }, { "name": "stem cell population maintenance", "id": "GO:0019827", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019827", "evidence": [ { "database": "UniProtKB", "id": "D3ZY52", "url": "https://www.uniprot.org/uniprotkb/D3ZY52" } ], "pmid": "" }, { "name": "mesoderm formation", "id": "GO:0001707", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001707", "evidence": [ { "database": "UniProtKB", "id": "D3ZY52", "url": "https://www.uniprot.org/uniprotkb/D3ZY52" } ], "pmid": "" }, { "name": "cerebral cortex regionalization", "id": "GO:0021796", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021796", "evidence": [ { "database": "UniProtKB", "id": "D3ZY52", "url": "https://www.uniprot.org/uniprotkb/D3ZY52" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "D3ZY52", "url": "https://www.uniprot.org/uniprotkb/D3ZY52" } ], "pmid": "" }, { "name": "skeletal muscle cell differentiation", "id": "GO:0035914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035914", "evidence": [ { "database": "UniProtKB", "id": "D3ZY52", "url": "https://www.uniprot.org/uniprotkb/D3ZY52" } ], "pmid": "" }, { "name": "neurogenesis", "id": "GO:0022008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022008", "evidence": [ { "database": "UniProtKB", "id": "D3ZY52", "url": "https://www.uniprot.org/uniprotkb/D3ZY52" } ], "pmid": "" }, { "name": "cerebral cortex neuron differentiation", "id": "GO:0021895", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021895", "evidence": [ { "database": "UniProtKB", "id": "D3ZY52", "url": "https://www.uniprot.org/uniprotkb/D3ZY52" } ], "pmid": "" }, { "name": "endoderm formation", "id": "GO:0001706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001706", "evidence": [ { "database": "UniProtKB", "id": "D3ZY52", "url": "https://www.uniprot.org/uniprotkb/D3ZY52" } ], "pmid": "" }, { "name": "cardioblast differentiation", "id": "GO:0010002", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010002", "evidence": [ { "database": "UniProtKB", "id": "D3ZY52", "url": "https://www.uniprot.org/uniprotkb/D3ZY52" } ], "pmid": "" }, { "name": "gene expression", "id": "GO:0010467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010467", "evidence": [ { "database": "UniProtKB", "id": "D3ZY52", "url": "https://www.uniprot.org/uniprotkb/D3ZY52" } ], "pmid": "" }, { "name": "blastocyst development", "id": "GO:0001824", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001824", "evidence": [ { "database": "UniProtKB", "id": "D3ZY52", "url": "https://www.uniprot.org/uniprotkb/D3ZY52" } ], "pmid": "" }, { "name": "olfactory bulb development", "id": "GO:0021772", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021772", "evidence": [ { "database": "UniProtKB", "id": "D3ZY52", "url": "https://www.uniprot.org/uniprotkb/D3ZY52" } ], "pmid": "" } ], "molecular_function": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "D3ZY52", "url": "https://www.uniprot.org/uniprotkb/D3ZY52" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "D3ZY52", "url": "https://www.uniprot.org/uniprotkb/D3ZY52" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "D3ZY52", "url": "https://www.uniprot.org/uniprotkb/D3ZY52" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "D3ZY52", "url": "https://www.uniprot.org/uniprotkb/D3ZY52" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "D3ZY52", "url": "https://www.uniprot.org/uniprotkb/D3ZY52" } ], "pmid": "" }, { "name": "chromatin DNA binding", "id": "GO:0031490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031490", "evidence": [ { "database": "UniProtKB", "id": "D3ZY52", "url": "https://www.uniprot.org/uniprotkb/D3ZY52" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "D3ZY52", "url": "https://www.uniprot.org/uniprotkb/D3ZY52" } ], "pmid": "" }, { "name": "RNA polymerase II-specific DNA-binding transcription factor binding", "id": "GO:0061629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061629", "evidence": [ { "database": "UniProtKB", "id": "D3ZY52", "url": "https://www.uniprot.org/uniprotkb/D3ZY52" } ], "pmid": "" }, { "name": "sequence-specific double-stranded DNA binding", "id": "GO:1990837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990837", "evidence": [ { "database": "UniProtKB", "id": "D3ZY52", "url": "https://www.uniprot.org/uniprotkb/D3ZY52" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D3ZY52", "url": "https://www.uniprot.org/uniprotkb/D3ZY52" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "D3ZY52", "url": "https://www.uniprot.org/uniprotkb/D3ZY52" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "D3ZY52-1", "start_pos": "478", "end_pos": "478", "site_lbl": "Thr478", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 478, "start_aa": "Thr", "end_pos": 478, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr478", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "D3ZY52-1" }, { "uniprot_canonical_ac": "D3ZYB8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZYB8", "url": "https://www.uniprot.org/uniprotkb/D3ZYB8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 3063, "chemical_mass": 341668.0, "gene_names": "Tex15;Tex15", "protein_name": "", "disease": [ { "disease_id": "DOID:0111920", "name": "spermatogenic failure 25", "description": "A spermatogenic failure characterized by maturation arrest at the primary spermatocyte stage resulting in severe oligozoospermia or azoospermia, small testes, and infertility that has_material_basis_in homozygous or compound heterozygous mutation in the TEX15 gene on chromosome 8p12.", "url": "https://disease-ontology.org/term/DOID:0111920", "evidence": [ { "id": "0111920", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111920" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D3ZYB8", "url": "https://www.uniprot.org/uniprotkb/D3ZYB8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "D3ZYB8", "url": "https://www.uniprot.org/uniprotkb/D3ZYB8" } ], "pmid": "" } ], "biological_process": [ { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "D3ZYB8", "url": "https://www.uniprot.org/uniprotkb/D3ZYB8" } ], "pmid": "" }, { "name": "fertilization", "id": "GO:0009566", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009566", "evidence": [ { "database": "UniProtKB", "id": "D3ZYB8", "url": "https://www.uniprot.org/uniprotkb/D3ZYB8" } ], "pmid": "" }, { "name": "homeostasis of number of cells within a tissue", "id": "GO:0048873", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048873", "evidence": [ { "database": "UniProtKB", "id": "D3ZYB8", "url": "https://www.uniprot.org/uniprotkb/D3ZYB8" } ], "pmid": "" }, { "name": "regulation of protein localization", "id": "GO:0032880", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032880", "evidence": [ { "database": "UniProtKB", "id": "D3ZYB8", "url": "https://www.uniprot.org/uniprotkb/D3ZYB8" } ], "pmid": "" }, { "name": "synaptonemal complex assembly", "id": "GO:0007130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007130", "evidence": [ { "database": "UniProtKB", "id": "D3ZYB8", "url": "https://www.uniprot.org/uniprotkb/D3ZYB8" } ], "pmid": "" }, { "name": "male meiotic nuclear division", "id": "GO:0007140", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007140", "evidence": [ { "database": "UniProtKB", "id": "D3ZYB8", "url": "https://www.uniprot.org/uniprotkb/D3ZYB8" } ], "pmid": "" }, { "name": "male genitalia development", "id": "GO:0030539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030539", "evidence": [ { "database": "UniProtKB", "id": "D3ZYB8", "url": "https://www.uniprot.org/uniprotkb/D3ZYB8" } ], "pmid": "" }, { "name": "homologous chromosome pairing at meiosis", "id": "GO:0007129", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007129", "evidence": [ { "database": "UniProtKB", "id": "D3ZYB8", "url": "https://www.uniprot.org/uniprotkb/D3ZYB8" } ], "pmid": "" }, { "name": "DNA methylation-dependent constitutive heterochromatin formation", "id": "GO:0006346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006346", "evidence": [ { "database": "UniProtKB", "id": "D3ZYB8", "url": "https://www.uniprot.org/uniprotkb/D3ZYB8" } ], "pmid": "" }, { "name": "protein localization to chromosome", "id": "GO:0034502", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034502", "evidence": [ { "database": "UniProtKB", "id": "D3ZYB8", "url": "https://www.uniprot.org/uniprotkb/D3ZYB8" } ], "pmid": "" }, { "name": "regulation of double-strand break repair via homologous recombination", "id": "GO:0010569", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010569", "evidence": [ { "database": "UniProtKB", "id": "D3ZYB8", "url": "https://www.uniprot.org/uniprotkb/D3ZYB8" } ], "pmid": "" }, { "name": "transposable element silencing", "id": "GO:0010526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010526", "evidence": [ { "database": "UniProtKB", "id": "D3ZYB8", "url": "https://www.uniprot.org/uniprotkb/D3ZYB8" } ], "pmid": "" }, { "name": "transposable element silencing by piRNA-mediated DNA methylation", "id": "GO:0141196", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141196", "evidence": [ { "database": "UniProtKB", "id": "D3ZYB8", "url": "https://www.uniprot.org/uniprotkb/D3ZYB8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZYB8-1" }, { "uniprot_canonical_ac": "D3ZYE4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZYE4", "url": "https://www.uniprot.org/uniprotkb/D3ZYE4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 320, "chemical_mass": 35815.0, "gene_names": "Or9i13;Olr378;Or9i13", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "D3ZYE4", "url": "https://www.uniprot.org/uniprotkb/D3ZYE4" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "D3ZYE4", "url": "https://www.uniprot.org/uniprotkb/D3ZYE4" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "D3ZYE4", "url": "https://www.uniprot.org/uniprotkb/D3ZYE4" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "D3ZYE4", "url": "https://www.uniprot.org/uniprotkb/D3ZYE4" } ], "pmid": "" } ], "biological_process": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "D3ZYE4", "url": "https://www.uniprot.org/uniprotkb/D3ZYE4" } ], "pmid": "" }, { "name": "sensory perception of smell", "id": "GO:0007608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007608", "evidence": [ { "database": "UniProtKB", "id": "D3ZYE4", "url": "https://www.uniprot.org/uniprotkb/D3ZYE4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZYE4-1" }, { "uniprot_canonical_ac": "D3ZYJ2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZYJ2", "url": "https://www.uniprot.org/uniprotkb/D3ZYJ2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 127, "chemical_mass": 14251.0, "gene_names": "Slc51b;Ostbeta;Ostb;RGD1565748;Slc51b", "protein_name": "", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "D3ZYJ2", "url": "https://www.uniprot.org/uniprotkb/D3ZYJ2" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "D3ZYJ2", "url": "https://www.uniprot.org/uniprotkb/D3ZYJ2" } ], "pmid": "" }, { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "D3ZYJ2", "url": "https://www.uniprot.org/uniprotkb/D3ZYJ2" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "D3ZYJ2", "url": "https://www.uniprot.org/uniprotkb/D3ZYJ2" } ], "pmid": "" } ], "molecular_function": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "D3ZYJ2", "url": "https://www.uniprot.org/uniprotkb/D3ZYJ2" } ], "pmid": "" }, { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "D3ZYJ2", "url": "https://www.uniprot.org/uniprotkb/D3ZYJ2" } ], "pmid": "" }, { "name": "bile acid transmembrane transporter activity", "id": "GO:0015125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015125", "evidence": [ { "database": "UniProtKB", "id": "D3ZYJ2", "url": "https://www.uniprot.org/uniprotkb/D3ZYJ2" } ], "pmid": "" } ], "biological_process": [ { "name": "bile acid and bile salt transport", "id": "GO:0015721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015721", "evidence": [ { "database": "UniProtKB", "id": "D3ZYJ2", "url": "https://www.uniprot.org/uniprotkb/D3ZYJ2" } ], "pmid": "" }, { "name": "regulation of protein stability", "id": "GO:0031647", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031647", "evidence": [ { "database": "UniProtKB", "id": "D3ZYJ2", "url": "https://www.uniprot.org/uniprotkb/D3ZYJ2" } ], "pmid": "" }, { "name": "positive regulation of protein targeting to membrane", "id": "GO:0090314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090314", "evidence": [ { "database": "UniProtKB", "id": "D3ZYJ2", "url": "https://www.uniprot.org/uniprotkb/D3ZYJ2" } ], "pmid": "" }, { "name": "positive regulation of protein exit from endoplasmic reticulum", "id": "GO:0070863", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070863", "evidence": [ { "database": "UniProtKB", "id": "D3ZYJ2", "url": "https://www.uniprot.org/uniprotkb/D3ZYJ2" } ], "pmid": "" }, { "name": "positive regulation of glycoprotein biosynthetic process", "id": "GO:0010560", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010560", "evidence": [ { "database": "UniProtKB", "id": "D3ZYJ2", "url": "https://www.uniprot.org/uniprotkb/D3ZYJ2" } ], "pmid": "" }, { "name": "bile acid secretion", "id": "GO:0032782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032782", "evidence": [ { "database": "UniProtKB", "id": "D3ZYJ2", "url": "https://www.uniprot.org/uniprotkb/D3ZYJ2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZYJ2-1" }, { "uniprot_canonical_ac": "D3ZYP9-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZYP9", "url": "https://www.uniprot.org/uniprotkb/D3ZYP9" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1093, "chemical_mass": 119203.0, "gene_names": "Nlrc3;Nlrc3-ps1", "protein_name": "", "disease": [], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "D3ZYP9", "url": "https://www.uniprot.org/uniprotkb/D3ZYP9" } ], "pmid": "" }, { "name": "phosphatidylinositol 3-kinase regulatory subunit binding", "id": "GO:0036312", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036312", "evidence": [ { "database": "UniProtKB", "id": "D3ZYP9", "url": "https://www.uniprot.org/uniprotkb/D3ZYP9" } ], "pmid": "" }, { "name": "molecular function inhibitor activity", "id": "GO:0140678", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140678", "evidence": [ { "database": "UniProtKB", "id": "D3ZYP9", "url": "https://www.uniprot.org/uniprotkb/D3ZYP9" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "D3ZYP9", "url": "https://www.uniprot.org/uniprotkb/D3ZYP9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "D3ZYP9", "url": "https://www.uniprot.org/uniprotkb/D3ZYP9" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "D3ZYP9", "url": "https://www.uniprot.org/uniprotkb/D3ZYP9" } ], "pmid": "" }, { "name": "canonical inflammasome complex", "id": "GO:0061702", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061702", "evidence": [ { "database": "UniProtKB", "id": "D3ZYP9", "url": "https://www.uniprot.org/uniprotkb/D3ZYP9" } ], "pmid": "" } ], "biological_process": [ { "name": "inflammatory response", "id": "GO:0006954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006954", "evidence": [ { "database": "UniProtKB", "id": "D3ZYP9", "url": "https://www.uniprot.org/uniprotkb/D3ZYP9" } ], "pmid": "" }, { "name": "response to lipopolysaccharide", "id": "GO:0032496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032496", "evidence": [ { "database": "UniProtKB", "id": "D3ZYP9", "url": "https://www.uniprot.org/uniprotkb/D3ZYP9" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "D3ZYP9", "url": "https://www.uniprot.org/uniprotkb/D3ZYP9" } ], "pmid": "" }, { "name": "negative regulation of interleukin-1 beta production", "id": "GO:0032691", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032691", "evidence": [ { "database": "UniProtKB", "id": "D3ZYP9", "url": "https://www.uniprot.org/uniprotkb/D3ZYP9" } ], "pmid": "" }, { "name": "negative regulation of interleukin-6 production", "id": "GO:0032715", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032715", "evidence": [ { "database": "UniProtKB", "id": "D3ZYP9", "url": "https://www.uniprot.org/uniprotkb/D3ZYP9" } ], "pmid": "" }, { "name": "negative regulation of tumor necrosis factor production", "id": "GO:0032720", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032720", "evidence": [ { "database": "UniProtKB", "id": "D3ZYP9", "url": "https://www.uniprot.org/uniprotkb/D3ZYP9" } ], "pmid": "" }, { "name": "T cell activation", "id": "GO:0042110", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042110", "evidence": [ { "database": "UniProtKB", "id": "D3ZYP9", "url": "https://www.uniprot.org/uniprotkb/D3ZYP9" } ], "pmid": "" }, { "name": "negative regulation of epithelial cell proliferation", "id": "GO:0050680", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050680", "evidence": [ { "database": "UniProtKB", "id": "D3ZYP9", "url": "https://www.uniprot.org/uniprotkb/D3ZYP9" } ], "pmid": "" }, { "name": "negative regulation of inflammatory response", "id": "GO:0050728", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050728", "evidence": [ { "database": "UniProtKB", "id": "D3ZYP9", "url": "https://www.uniprot.org/uniprotkb/D3ZYP9" } ], "pmid": "" }, { "name": "negative regulation of canonical NF-kappaB signal transduction", "id": "GO:0043124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043124", "evidence": [ { "database": "UniProtKB", "id": "D3ZYP9", "url": "https://www.uniprot.org/uniprotkb/D3ZYP9" } ], "pmid": "" }, { "name": "negative regulation of fibroblast proliferation", "id": "GO:0048147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048147", "evidence": [ { "database": "UniProtKB", "id": "D3ZYP9", "url": "https://www.uniprot.org/uniprotkb/D3ZYP9" } ], "pmid": "" }, { "name": "negative regulation of non-canonical NF-kappaB signal transduction", "id": "GO:1901223", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901223", "evidence": [ { "database": "UniProtKB", "id": "D3ZYP9", "url": "https://www.uniprot.org/uniprotkb/D3ZYP9" } ], "pmid": "" }, { "name": "negative regulation of cytokine production involved in inflammatory response", "id": "GO:1900016", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900016", "evidence": [ { "database": "UniProtKB", "id": "D3ZYP9", "url": "https://www.uniprot.org/uniprotkb/D3ZYP9" } ], "pmid": "" }, { "name": "canonical NF-kappaB signal transduction", "id": "GO:0007249", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007249", "evidence": [ { "database": "UniProtKB", "id": "D3ZYP9", "url": "https://www.uniprot.org/uniprotkb/D3ZYP9" } ], "pmid": "" }, { "name": "negative regulation of interleukin-12 production", "id": "GO:0032695", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032695", "evidence": [ { "database": "UniProtKB", "id": "D3ZYP9", "url": "https://www.uniprot.org/uniprotkb/D3ZYP9" } ], "pmid": "" }, { "name": "negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction", "id": "GO:0051898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051898", "evidence": [ { "database": "UniProtKB", "id": "D3ZYP9", "url": "https://www.uniprot.org/uniprotkb/D3ZYP9" } ], "pmid": "" }, { "name": "negative regulation of interferon-beta production", "id": "GO:0032688", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032688", "evidence": [ { "database": "UniProtKB", "id": "D3ZYP9", "url": "https://www.uniprot.org/uniprotkb/D3ZYP9" } ], "pmid": "" }, { "name": "regulation of protein ubiquitination", "id": "GO:0031396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031396", "evidence": [ { "database": "UniProtKB", "id": "D3ZYP9", "url": "https://www.uniprot.org/uniprotkb/D3ZYP9" } ], "pmid": "" }, { "name": "negative regulation of innate immune response", "id": "GO:0045824", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045824", "evidence": [ { "database": "UniProtKB", "id": "D3ZYP9", "url": "https://www.uniprot.org/uniprotkb/D3ZYP9" } ], "pmid": "" }, { "name": "negative regulation of NLRP3 inflammasome complex assembly", "id": "GO:1900226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900226", "evidence": [ { "database": "UniProtKB", "id": "D3ZYP9", "url": "https://www.uniprot.org/uniprotkb/D3ZYP9" } ], "pmid": "" }, { "name": "negative regulation of interferon-alpha production", "id": "GO:0032687", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032687", "evidence": [ { "database": "UniProtKB", "id": "D3ZYP9", "url": "https://www.uniprot.org/uniprotkb/D3ZYP9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZYP9-1" }, { "uniprot_canonical_ac": "D3ZZ09-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZZ09", "url": "https://www.uniprot.org/uniprotkb/D3ZZ09" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 327, "chemical_mass": 36158.0, "gene_names": "Vgll3;RGD1560030;Vgll3", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D3ZZ09", "url": "https://www.uniprot.org/uniprotkb/D3ZZ09" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "D3ZZ09", "url": "https://www.uniprot.org/uniprotkb/D3ZZ09" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "D3ZZ09", "url": "https://www.uniprot.org/uniprotkb/D3ZZ09" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "D3ZZ09-1", "start_pos": "205", "end_pos": "205", "site_lbl": "Thr205", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 205, "start_aa": "Thr", "end_pos": 205, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr205", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "D3ZZ09-1" }, { "uniprot_canonical_ac": "D3ZZ61-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZZ61", "url": "https://www.uniprot.org/uniprotkb/D3ZZ61" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 734, "chemical_mass": 78547.0, "gene_names": "Cep68;Cep68;RGD1309101", "protein_name": "Centrosomal protein of 68 kDa", "disease": [], "cellular_component": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "D3ZZ61", "url": "https://www.uniprot.org/uniprotkb/D3ZZ61" } ], "pmid": "" }, { "name": "centriolar satellite", "id": "GO:0034451", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034451", "evidence": [ { "database": "UniProtKB", "id": "D3ZZ61", "url": "https://www.uniprot.org/uniprotkb/D3ZZ61" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "D3ZZ61", "url": "https://www.uniprot.org/uniprotkb/D3ZZ61" } ], "pmid": "" }, { "name": "protein domain specific binding", "id": "GO:0019904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019904", "evidence": [ { "database": "UniProtKB", "id": "D3ZZ61", "url": "https://www.uniprot.org/uniprotkb/D3ZZ61" } ], "pmid": "" } ], "biological_process": [ { "name": "centrosome cycle", "id": "GO:0007098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007098", "evidence": [ { "database": "UniProtKB", "id": "D3ZZ61", "url": "https://www.uniprot.org/uniprotkb/D3ZZ61" } ], "pmid": "" }, { "name": "centriole-centriole cohesion", "id": "GO:0010457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010457", "evidence": [ { "database": "UniProtKB", "id": "D3ZZ61", "url": "https://www.uniprot.org/uniprotkb/D3ZZ61" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZZ61-1" }, { "uniprot_canonical_ac": "D3ZZK3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 986, "chemical_mass": 109838.0, "gene_names": "Epha4;Epha4;RGD1560587", "protein_name": "receptor protein-tyrosine kinase", "disease": [ { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:3602", "name": "toxic encephalopathy", "description": "A nervous system disease that results from exposure to neurotoxicants and is characterized by an altered mental status, memory loss, and visual problems.", "url": "https://disease-ontology.org/term/DOID:3602", "evidence": [ { "id": "3602", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3602" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "neuromuscular junction", "id": "GO:0031594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031594", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "dendritic spine", "id": "GO:0043197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043197", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "dendritic shaft", "id": "GO:0043198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043198", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "perikaryon", "id": "GO:0043204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043204", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "axon terminus", "id": "GO:0043679", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043679", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "postsynaptic membrane", "id": "GO:0045211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045211", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "filopodium", "id": "GO:0030175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030175", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "cell body", "id": "GO:0044297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044297", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "cell projection", "id": "GO:0042995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042995", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "presynaptic membrane", "id": "GO:0042734", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042734", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "axonal growth cone", "id": "GO:0044295", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044295", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "Schaffer collateral - CA1 synapse", "id": "GO:0098685", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098685", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of axonogenesis", "id": "GO:0050770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050770", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "innervation", "id": "GO:0060384", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060384", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "neuron projection guidance", "id": "GO:0097485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097485", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "negative regulation of cell adhesion", "id": "GO:0007162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007162", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "positive regulation of cell migration", "id": "GO:0030335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030335", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "regulation of GTPase activity", "id": "GO:0043087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043087", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "positive regulation of cell adhesion", "id": "GO:0045785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045785", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "positive regulation of JNK cascade", "id": "GO:0046330", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046330", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "ephrin receptor signaling pathway", "id": "GO:0048013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048013", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "negative regulation of long-term synaptic potentiation", "id": "GO:1900272", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900272", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "positive regulation of amyloid-beta formation", "id": "GO:1902004", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902004", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "cellular response to amyloid-beta", "id": "GO:1904646", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904646", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "negative regulation of cell migration", "id": "GO:0030336", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030336", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "negative regulation of neuron projection development", "id": "GO:0010977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010977", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "negative regulation of neuron apoptotic process", "id": "GO:0043524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043524", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "protein stabilization", "id": "GO:0050821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050821", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "adult walking behavior", "id": "GO:0007628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007628", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "negative regulation of ERK1 and ERK2 cascade", "id": "GO:0070373", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070373", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "regulation of modification of synaptic structure", "id": "GO:1905244", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905244", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "adherens junction organization", "id": "GO:0034332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034332", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "positive regulation of dendrite morphogenesis", "id": "GO:0050775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050775", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "regulation of dendritic spine morphogenesis", "id": "GO:0061001", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061001", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "negative regulation of proteolysis involved in protein catabolic process", "id": "GO:1903051", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903051", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "negative regulation of cellular response to hypoxia", "id": "GO:1900038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900038", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "fasciculation of sensory neuron axon", "id": "GO:0097155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097155", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "fasciculation of motor neuron axon", "id": "GO:0097156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097156", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "neuron projection fasciculation", "id": "GO:0106030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106030", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "positive regulation of intracellular signal transduction", "id": "GO:1902533", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902533", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "motor neuron axon guidance", "id": "GO:0008045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008045", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "synapse pruning", "id": "GO:0098883", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098883", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "nephric duct morphogenesis", "id": "GO:0072178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072178", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "glial cell migration", "id": "GO:0008347", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008347", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "corticospinal tract morphogenesis", "id": "GO:0021957", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021957", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "negative regulation of epithelial to mesenchymal transition", "id": "GO:0010719", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010719", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "negative regulation of axon regeneration", "id": "GO:0048681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048681", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "regulation of astrocyte differentiation", "id": "GO:0048710", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048710", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "cochlea development", "id": "GO:0090102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090102", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "positive regulation of leukocyte adhesion to arterial endothelial cell", "id": "GO:1904999", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904999", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "positive regulation of amyloid precursor protein catabolic process", "id": "GO:1902993", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902993", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "regulation of synapse pruning", "id": "GO:1905806", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905806", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "ephrin receptor binding", "id": "GO:0046875", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046875", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "transmembrane receptor protein tyrosine kinase activity", "id": "GO:0004714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004714", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "kinase activity", "id": "GO:0016301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016301", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "DH domain binding", "id": "GO:0097161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097161", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "transmembrane-ephrin receptor activity", "id": "GO:0005005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005005", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "protein tyrosine kinase binding", "id": "GO:1990782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990782", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "PH domain binding", "id": "GO:0042731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042731", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "ephrin receptor activity", "id": "GO:0005003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005003", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" }, { "name": "GPI-linked ephrin receptor activity", "id": "GO:0005004", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005004", "evidence": [ { "database": "UniProtKB", "id": "D3ZZK3", "url": "https://www.uniprot.org/uniprotkb/D3ZZK3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZZK3-1" }, { "uniprot_canonical_ac": "D3ZZT7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZZT7", "url": "https://www.uniprot.org/uniprotkb/D3ZZT7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 625, "chemical_mass": 71057.0, "gene_names": "Pp2d1;Pp2d1;RGD1564811", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D3ZZT7", "url": "https://www.uniprot.org/uniprotkb/D3ZZT7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "D3ZZT7", "url": "https://www.uniprot.org/uniprotkb/D3ZZT7" } ], "pmid": "" } ], "biological_process": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "D3ZZT7", "url": "https://www.uniprot.org/uniprotkb/D3ZZT7" } ], "pmid": "" }, { "name": "negative regulation of MAPK cascade", "id": "GO:0043409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043409", "evidence": [ { "database": "UniProtKB", "id": "D3ZZT7", "url": "https://www.uniprot.org/uniprotkb/D3ZZT7" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein serine/threonine phosphatase activity", "id": "GO:0004722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004722", "evidence": [ { "database": "UniProtKB", "id": "D3ZZT7", "url": "https://www.uniprot.org/uniprotkb/D3ZZT7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D3ZZT7-1" }, { "uniprot_canonical_ac": "D3ZZW8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3ZZW8", "url": "https://www.uniprot.org/uniprotkb/D3ZZW8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 988, "chemical_mass": 113500.0, "gene_names": "Lvrn;Aqpep", "protein_name": "Aminopeptidase", "disease": [], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "D3ZZW8", "url": "https://www.uniprot.org/uniprotkb/D3ZZW8" } ], "pmid": "" } ], "molecular_function": [ { "name": "metallopeptidase activity", "id": "GO:0008237", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008237", "evidence": [ { "database": "UniProtKB", "id": "D3ZZW8", "url": "https://www.uniprot.org/uniprotkb/D3ZZW8" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "D3ZZW8", "url": "https://www.uniprot.org/uniprotkb/D3ZZW8" } ], "pmid": "" }, { "name": "aminopeptidase activity", "id": "GO:0004177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004177", "evidence": [ { "database": "UniProtKB", "id": "D3ZZW8", "url": "https://www.uniprot.org/uniprotkb/D3ZZW8" } ], "pmid": "" } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "D3ZZW8", "url": "https://www.uniprot.org/uniprotkb/D3ZZW8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "D3ZZW8-1", "start_pos": "70", "end_pos": "70", "site_lbl": "Thr70", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 70, "start_aa": "Thr", "end_pos": 70, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr70", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "D3ZZW8-1" }, { "uniprot_canonical_ac": "D4A0C0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4A0C0", "url": "https://www.uniprot.org/uniprotkb/D4A0C0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 315, "chemical_mass": 34853.0, "gene_names": "Or3a1f;Olr1511;Or3a1f;ratchr10-61433167-61434114_ORF", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "D4A0C0", "url": "https://www.uniprot.org/uniprotkb/D4A0C0" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "D4A0C0", "url": "https://www.uniprot.org/uniprotkb/D4A0C0" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "D4A0C0", "url": "https://www.uniprot.org/uniprotkb/D4A0C0" } ], "pmid": "" } ], "biological_process": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "D4A0C0", "url": "https://www.uniprot.org/uniprotkb/D4A0C0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D4A0C0-1" }, { "uniprot_canonical_ac": "D4A0C3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4A0C3", "url": "https://www.uniprot.org/uniprotkb/D4A0C3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 788, "chemical_mass": 88754.0, "gene_names": "Hid1;Hid1;RGD1311422", "protein_name": "Protein HID1", "disease": [ { "disease_id": "DOID:0070391", "name": "developmental and epileptic encephalopathy 105", "description": "A developmental and epileptic encephalopathy characterized by onset of seizures and pituitary insufficiency in the first weeks or months of life with profoundly impaired development that has_material_basis_in homozygous or compound heterozygous mutation in the HID1 gene on chromosome 17q25.", "url": "https://disease-ontology.org/term/DOID:0070391", "evidence": [ { "id": "0070391", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070391" } ], "weight": 0.0 } ], "biological_process": [ { "name": "vacuole fusion, non-autophagic", "id": "GO:0042144", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042144", "evidence": [ { "database": "UniProtKB", "id": "D4A0C3", "url": "https://www.uniprot.org/uniprotkb/D4A0C3" } ], "pmid": "" }, { "name": "response to glucose", "id": "GO:0009749", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009749", "evidence": [ { "database": "UniProtKB", "id": "D4A0C3", "url": "https://www.uniprot.org/uniprotkb/D4A0C3" } ], "pmid": "" }, { "name": "insulin processing", "id": "GO:0030070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030070", "evidence": [ { "database": "UniProtKB", "id": "D4A0C3", "url": "https://www.uniprot.org/uniprotkb/D4A0C3" } ], "pmid": "" }, { "name": "secretory granule maturation", "id": "GO:0061792", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061792", "evidence": [ { "database": "UniProtKB", "id": "D4A0C3", "url": "https://www.uniprot.org/uniprotkb/D4A0C3" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "D4A0C3", "url": "https://www.uniprot.org/uniprotkb/D4A0C3" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "D4A0C3", "url": "https://www.uniprot.org/uniprotkb/D4A0C3" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "D4A0C3", "url": "https://www.uniprot.org/uniprotkb/D4A0C3" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "D4A0C3", "url": "https://www.uniprot.org/uniprotkb/D4A0C3" } ], "pmid": "" }, { "name": "Golgi medial cisterna", "id": "GO:0005797", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005797", "evidence": [ { "database": "UniProtKB", "id": "D4A0C3", "url": "https://www.uniprot.org/uniprotkb/D4A0C3" } ], "pmid": "" }, { "name": "cytoplasmic microtubule", "id": "GO:0005881", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005881", "evidence": [ { "database": "UniProtKB", "id": "D4A0C3", "url": "https://www.uniprot.org/uniprotkb/D4A0C3" } ], "pmid": "" }, { "name": "Golgi trans cisterna", "id": "GO:0000138", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000138", "evidence": [ { "database": "UniProtKB", "id": "D4A0C3", "url": "https://www.uniprot.org/uniprotkb/D4A0C3" } ], "pmid": "" }, { "name": "cytoplasmic side of Golgi membrane", "id": "GO:0098548", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098548", "evidence": [ { "database": "UniProtKB", "id": "D4A0C3", "url": "https://www.uniprot.org/uniprotkb/D4A0C3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "D4A0C3-1", "start_pos": "620", "end_pos": "620", "site_lbl": "Thr620", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 620, "start_aa": "Thr", "end_pos": 620, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr620", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "D4A0C3-1", "start_pos": "653", "end_pos": "653", "site_lbl": "Ser653", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "D4A0C3", "url": "https://www.uniprot.org/uniprotkb/D4A0C3" } ] } ] }, { "uniprot_canonical_ac": "D4A0C3-1", "start_pos": "670", "end_pos": "670", "site_lbl": "Ser670", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "D4A0C3", "url": "https://www.uniprot.org/uniprotkb/D4A0C3" } ] } ] } ], "record_id": "D4A0C3-1" }, { "uniprot_canonical_ac": "D4A0W6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4A0W6", "url": "https://www.uniprot.org/uniprotkb/D4A0W6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 150, "chemical_mass": 17474.0, "gene_names": "Dppa3l1", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D4A0W6", "url": "https://www.uniprot.org/uniprotkb/D4A0W6" } ], "pmid": "" } ], "biological_process": [ { "name": "epigenetic programing of female pronucleus", "id": "GO:0044726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044726", "evidence": [ { "database": "UniProtKB", "id": "D4A0W6", "url": "https://www.uniprot.org/uniprotkb/D4A0W6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D4A0W6-1" }, { "uniprot_canonical_ac": "D4A123-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4A123", "url": "https://www.uniprot.org/uniprotkb/D4A123" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 706, "chemical_mass": 74146.0, "gene_names": "Prdm8", "protein_name": "PR domain zinc finger protein 8", "disease": [ { "disease_id": "DOID:0111445", "name": "progressive myoclonus epilepsy 10", "description": "A progressive myoclonus epilepsy characterized by onset of progressive myoclonus, ataxia, spasticity, dysarthria, and cognitive decline in the first decade of life that has_material_basis_in homozygous or compoud heterozygous mutation in the PRDM8 gene on chromosome 4q21.21.", "url": "https://disease-ontology.org/term/DOID:0111445", "evidence": [ { "id": "0111445", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111445" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "D4A123", "url": "https://www.uniprot.org/uniprotkb/D4A123" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "D4A123", "url": "https://www.uniprot.org/uniprotkb/D4A123" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "D4A123", "url": "https://www.uniprot.org/uniprotkb/D4A123" } ], "pmid": "" }, { "name": "histone methyltransferase activity", "id": "GO:0042054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042054", "evidence": [ { "database": "UniProtKB", "id": "D4A123", "url": "https://www.uniprot.org/uniprotkb/D4A123" } ], "pmid": "" }, { "name": "histone H3K9 methyltransferase activity", "id": "GO:0046974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046974", "evidence": [ { "database": "UniProtKB", "id": "D4A123", "url": "https://www.uniprot.org/uniprotkb/D4A123" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D4A123", "url": "https://www.uniprot.org/uniprotkb/D4A123" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "D4A123", "url": "https://www.uniprot.org/uniprotkb/D4A123" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "D4A123", "url": "https://www.uniprot.org/uniprotkb/D4A123" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "D4A123", "url": "https://www.uniprot.org/uniprotkb/D4A123" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "D4A123", "url": "https://www.uniprot.org/uniprotkb/D4A123" } ], "pmid": "" }, { "name": "central nervous system projection neuron axonogenesis", "id": "GO:0021952", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021952", "evidence": [ { "database": "UniProtKB", "id": "D4A123", "url": "https://www.uniprot.org/uniprotkb/D4A123" } ], "pmid": "" }, { "name": "oligodendrocyte development", "id": "GO:0014003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014003", "evidence": [ { "database": "UniProtKB", "id": "D4A123", "url": "https://www.uniprot.org/uniprotkb/D4A123" } ], "pmid": "" }, { "name": "neurogenesis", "id": "GO:0022008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022008", "evidence": [ { "database": "UniProtKB", "id": "D4A123", "url": "https://www.uniprot.org/uniprotkb/D4A123" } ], "pmid": "" }, { "name": "corpus callosum morphogenesis", "id": "GO:0021540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021540", "evidence": [ { "database": "UniProtKB", "id": "D4A123", "url": "https://www.uniprot.org/uniprotkb/D4A123" } ], "pmid": "" }, { "name": "corticospinal tract morphogenesis", "id": "GO:0021957", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021957", "evidence": [ { "database": "UniProtKB", "id": "D4A123", "url": "https://www.uniprot.org/uniprotkb/D4A123" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D4A123-1" }, { "uniprot_canonical_ac": "D4A1C5-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4A1C5", "url": "https://www.uniprot.org/uniprotkb/D4A1C5" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 197, "chemical_mass": 22615.0, "gene_names": "Spc24;RGD1307631;Spbc24;Spc24-ps1;Spc24", "protein_name": "Kinetochore protein Spc24", "disease": [], "cellular_component": [ { "name": "Ndc80 complex", "id": "GO:0031262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031262", "evidence": [ { "database": "UniProtKB", "id": "D4A1C5", "url": "https://www.uniprot.org/uniprotkb/D4A1C5" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "D4A1C5", "url": "https://www.uniprot.org/uniprotkb/D4A1C5" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "D4A1C5", "url": "https://www.uniprot.org/uniprotkb/D4A1C5" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "D4A1C5", "url": "https://www.uniprot.org/uniprotkb/D4A1C5" } ], "pmid": "" }, { "name": "outer kinetochore", "id": "GO:0000940", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000940", "evidence": [ { "database": "UniProtKB", "id": "D4A1C5", "url": "https://www.uniprot.org/uniprotkb/D4A1C5" } ], "pmid": "" } ], "biological_process": [ { "name": "chromosome segregation", "id": "GO:0007059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007059", "evidence": [ { "database": "UniProtKB", "id": "D4A1C5", "url": "https://www.uniprot.org/uniprotkb/D4A1C5" } ], "pmid": "" }, { "name": "attachment of spindle microtubules to kinetochore", "id": "GO:0008608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008608", "evidence": [ { "database": "UniProtKB", "id": "D4A1C5", "url": "https://www.uniprot.org/uniprotkb/D4A1C5" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "D4A1C5", "url": "https://www.uniprot.org/uniprotkb/D4A1C5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D4A1C5-1" }, { "uniprot_canonical_ac": "D4A1G8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4A1G8", "url": "https://www.uniprot.org/uniprotkb/D4A1G8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1575, "chemical_mass": 171695.0, "gene_names": "Cep170b;Cep170b", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "D4A1G8-1", "start_pos": "1345", "end_pos": "1345", "site_lbl": "Thr1345", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1345, "start_aa": "Thr", "end_pos": 1345, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1345", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "D4A1G8-1", "start_pos": "537", "end_pos": "537", "site_lbl": "Thr537", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 537, "start_aa": "Thr", "end_pos": 537, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr537", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "D4A1G8-1", "start_pos": "546", "end_pos": "546", "site_lbl": "Thr546", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 546, "start_aa": "Thr", "end_pos": 546, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr546", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "D4A1G8-1", "start_pos": "967", "end_pos": "967", "site_lbl": "Thr967", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 967, "start_aa": "Thr", "end_pos": 967, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr967", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "D4A1G8-1" }, { "uniprot_canonical_ac": "D4A1G9-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4A1G9", "url": "https://www.uniprot.org/uniprotkb/D4A1G9" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 312, "chemical_mass": 35112.0, "gene_names": "Or5w15;Olr584;Or5w15", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "D4A1G9", "url": "https://www.uniprot.org/uniprotkb/D4A1G9" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "D4A1G9", "url": "https://www.uniprot.org/uniprotkb/D4A1G9" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "D4A1G9", "url": "https://www.uniprot.org/uniprotkb/D4A1G9" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "D4A1G9", "url": "https://www.uniprot.org/uniprotkb/D4A1G9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D4A1G9-1" }, { "uniprot_canonical_ac": "D4A1I9-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4A1I9", "url": "https://www.uniprot.org/uniprotkb/D4A1I9" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 407, "chemical_mass": 46163.0, "gene_names": "Ppil6", "protein_name": "", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "D4A1I9", "url": "https://www.uniprot.org/uniprotkb/D4A1I9" } ], "pmid": "" } ], "molecular_function": [ { "name": "peptidyl-prolyl cis-trans isomerase activity", "id": "GO:0003755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003755", "evidence": [ { "database": "UniProtKB", "id": "D4A1I9", "url": "https://www.uniprot.org/uniprotkb/D4A1I9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D4A1I9-1" }, { "uniprot_canonical_ac": "D4A242-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4A242", "url": "https://www.uniprot.org/uniprotkb/D4A242" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 252, "chemical_mass": 27468.0, "gene_names": "LOC120102490;LOC120102490", "protein_name": "Insulin-induced gene protein", "disease": [], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "D4A242", "url": "https://www.uniprot.org/uniprotkb/D4A242" } ], "pmid": "" }, { "name": "SREBP-SCAP-Insig complex", "id": "GO:0032937", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032937", "evidence": [ { "database": "UniProtKB", "id": "D4A242", "url": "https://www.uniprot.org/uniprotkb/D4A242" } ], "pmid": "" } ], "biological_process": [ { "name": "cellular response to insulin stimulus", "id": "GO:0032869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032869", "evidence": [ { "database": "UniProtKB", "id": "D4A242", "url": "https://www.uniprot.org/uniprotkb/D4A242" } ], "pmid": "" }, { "name": "cholesterol biosynthetic process", "id": "GO:0006695", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006695", "evidence": [ { "database": "UniProtKB", "id": "D4A242", "url": "https://www.uniprot.org/uniprotkb/D4A242" } ], "pmid": "" }, { "name": "SREBP signaling pathway", "id": "GO:0032933", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032933", "evidence": [ { "database": "UniProtKB", "id": "D4A242", "url": "https://www.uniprot.org/uniprotkb/D4A242" } ], "pmid": "" }, { "name": "SREBP-SCAP complex retention in endoplasmic reticulum", "id": "GO:0036316", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036316", "evidence": [ { "database": "UniProtKB", "id": "D4A242", "url": "https://www.uniprot.org/uniprotkb/D4A242" } ], "pmid": "" } ], "molecular_function": [ { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "D4A242", "url": "https://www.uniprot.org/uniprotkb/D4A242" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D4A242-1" }, { "uniprot_canonical_ac": "D4A252-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4A252", "url": "https://www.uniprot.org/uniprotkb/D4A252" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 319, "chemical_mass": 35484.0, "gene_names": "Or13f5;LOC500460;Or13f5", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "D4A252", "url": "https://www.uniprot.org/uniprotkb/D4A252" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "D4A252", "url": "https://www.uniprot.org/uniprotkb/D4A252" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "D4A252", "url": "https://www.uniprot.org/uniprotkb/D4A252" } ], "pmid": "" } ], "biological_process": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "D4A252", "url": "https://www.uniprot.org/uniprotkb/D4A252" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D4A252-1" }, { "uniprot_canonical_ac": "D4A254-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4A254", "url": "https://www.uniprot.org/uniprotkb/D4A254" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1359, "chemical_mass": 150415.0, "gene_names": "Phlpp2;Phlpp2;Phlppl;RGD1562857", "protein_name": "PH domain leucine-rich repeat-containing protein phosphatase 2", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D4A254", "url": "https://www.uniprot.org/uniprotkb/D4A254" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "D4A254", "url": "https://www.uniprot.org/uniprotkb/D4A254" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "D4A254", "url": "https://www.uniprot.org/uniprotkb/D4A254" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "D4A254", "url": "https://www.uniprot.org/uniprotkb/D4A254" } ], "pmid": "" }, { "name": "intercellular bridge", "id": "GO:0045171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045171", "evidence": [ { "database": "UniProtKB", "id": "D4A254", "url": "https://www.uniprot.org/uniprotkb/D4A254" } ], "pmid": "" }, { "name": "photoreceptor inner segment", "id": "GO:0001917", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001917", "evidence": [ { "database": "UniProtKB", "id": "D4A254", "url": "https://www.uniprot.org/uniprotkb/D4A254" } ], "pmid": "" }, { "name": "mitotic spindle", "id": "GO:0072686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072686", "evidence": [ { "database": "UniProtKB", "id": "D4A254", "url": "https://www.uniprot.org/uniprotkb/D4A254" } ], "pmid": "" }, { "name": "photoreceptor outer segment membrane", "id": "GO:0042622", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042622", "evidence": [ { "database": "UniProtKB", "id": "D4A254", "url": "https://www.uniprot.org/uniprotkb/D4A254" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "D4A254", "url": "https://www.uniprot.org/uniprotkb/D4A254" } ], "pmid": "" }, { "name": "protein serine/threonine phosphatase activity", "id": "GO:0004722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004722", "evidence": [ { "database": "UniProtKB", "id": "D4A254", "url": "https://www.uniprot.org/uniprotkb/D4A254" } ], "pmid": "" } ], "biological_process": [ { "name": "hippocampus development", "id": "GO:0021766", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021766", "evidence": [ { "database": "UniProtKB", "id": "D4A254", "url": "https://www.uniprot.org/uniprotkb/D4A254" } ], "pmid": "" }, { "name": "protein dephosphorylation", "id": "GO:0006470", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006470", "evidence": [ { "database": "UniProtKB", "id": "D4A254", "url": "https://www.uniprot.org/uniprotkb/D4A254" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D4A254-1" }, { "uniprot_canonical_ac": "D4A275-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4A275", "url": "https://www.uniprot.org/uniprotkb/D4A275" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 444, "chemical_mass": 51353.0, "gene_names": "Gxylt2;Gxylt2;LOC100365223", "protein_name": "UDP-D-xylose:beta-D-glucoside alpha-1,3-D-xylosyltransferase", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "D4A275", "url": "https://www.uniprot.org/uniprotkb/D4A275" } ], "pmid": "" } ], "biological_process": [ { "name": "protein O-linked glycosylation via N-acetyl-galactosamine", "id": "GO:0016266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016266", "evidence": [ { "database": "UniProtKB", "id": "D4A275", "url": "https://www.uniprot.org/uniprotkb/D4A275" } ], "pmid": "" }, { "name": "protein O-linked glycosylation via glucose", "id": "GO:0180059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0180059", "evidence": [ { "database": "UniProtKB", "id": "D4A275", "url": "https://www.uniprot.org/uniprotkb/D4A275" } ], "pmid": "" } ], "molecular_function": [ { "name": "UDP-xylosyltransferase activity", "id": "GO:0035252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035252", "evidence": [ { "database": "UniProtKB", "id": "D4A275", "url": "https://www.uniprot.org/uniprotkb/D4A275" } ], "pmid": "" }, { "name": "UDP-D-xylose:beta-D-glucoside alpha-1,3-D-xylosyltransferase activity", "id": "GO:0140563", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140563", "evidence": [ { "database": "UniProtKB", "id": "D4A275", "url": "https://www.uniprot.org/uniprotkb/D4A275" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D4A275-1" }, { "uniprot_canonical_ac": "D4A287-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4A287", "url": "https://www.uniprot.org/uniprotkb/D4A287" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 352, "chemical_mass": 34973.0, "gene_names": "Bhlhe22;Bhlhb5;Bhlhe22", "protein_name": "Class E basic helix-loop-helix protein 22", "disease": [], "biological_process": [ { "name": "retina morphogenesis in camera-type eye", "id": "GO:0060042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060042", "evidence": [ { "database": "UniProtKB", "id": "D4A287", "url": "https://www.uniprot.org/uniprotkb/D4A287" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "D4A287", "url": "https://www.uniprot.org/uniprotkb/D4A287" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "D4A287", "url": "https://www.uniprot.org/uniprotkb/D4A287" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "D4A287", "url": "https://www.uniprot.org/uniprotkb/D4A287" } ], "pmid": "" }, { "name": "neuron differentiation", "id": "GO:0030182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030182", "evidence": [ { "database": "UniProtKB", "id": "D4A287", "url": "https://www.uniprot.org/uniprotkb/D4A287" } ], "pmid": "" }, { "name": "central nervous system projection neuron axonogenesis", "id": "GO:0021952", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021952", "evidence": [ { "database": "UniProtKB", "id": "D4A287", "url": "https://www.uniprot.org/uniprotkb/D4A287" } ], "pmid": "" }, { "name": "cerebral cortex regionalization", "id": "GO:0021796", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021796", "evidence": [ { "database": "UniProtKB", "id": "D4A287", "url": "https://www.uniprot.org/uniprotkb/D4A287" } ], "pmid": "" }, { "name": "axon development", "id": "GO:0061564", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061564", "evidence": [ { "database": "UniProtKB", "id": "D4A287", "url": "https://www.uniprot.org/uniprotkb/D4A287" } ], "pmid": "" }, { "name": "corpus callosum morphogenesis", "id": "GO:0021540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021540", "evidence": [ { "database": "UniProtKB", "id": "D4A287", "url": "https://www.uniprot.org/uniprotkb/D4A287" } ], "pmid": "" }, { "name": "corticospinal tract morphogenesis", "id": "GO:0021957", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021957", "evidence": [ { "database": "UniProtKB", "id": "D4A287", "url": "https://www.uniprot.org/uniprotkb/D4A287" } ], "pmid": "" }, { "name": "retinal bipolar neuron differentiation", "id": "GO:0060040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060040", "evidence": [ { "database": "UniProtKB", "id": "D4A287", "url": "https://www.uniprot.org/uniprotkb/D4A287" } ], "pmid": "" }, { "name": "sensory organ development", "id": "GO:0007423", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007423", "evidence": [ { "database": "UniProtKB", "id": "D4A287", "url": "https://www.uniprot.org/uniprotkb/D4A287" } ], "pmid": "" }, { "name": "anterior commissure morphogenesis", "id": "GO:0021960", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021960", "evidence": [ { "database": "UniProtKB", "id": "D4A287", "url": "https://www.uniprot.org/uniprotkb/D4A287" } ], "pmid": "" } ], "molecular_function": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "D4A287", "url": "https://www.uniprot.org/uniprotkb/D4A287" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "D4A287", "url": "https://www.uniprot.org/uniprotkb/D4A287" } ], "pmid": "" }, { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "D4A287", "url": "https://www.uniprot.org/uniprotkb/D4A287" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "D4A287", "url": "https://www.uniprot.org/uniprotkb/D4A287" } ], "pmid": "" }, { "name": "E-box binding", "id": "GO:0070888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070888", "evidence": [ { "database": "UniProtKB", "id": "D4A287", "url": "https://www.uniprot.org/uniprotkb/D4A287" } ], "pmid": "" }, { "name": "sequence-specific double-stranded DNA binding", "id": "GO:1990837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990837", "evidence": [ { "database": "UniProtKB", "id": "D4A287", "url": "https://www.uniprot.org/uniprotkb/D4A287" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D4A287", "url": "https://www.uniprot.org/uniprotkb/D4A287" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "D4A287-1", "start_pos": "193", "end_pos": "193", "site_lbl": "Thr193", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 193, "start_aa": "Thr", "end_pos": 193, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr193", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "D4A287-1" }, { "uniprot_canonical_ac": "D4A327-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4A327", "url": "https://www.uniprot.org/uniprotkb/D4A327" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 807, "chemical_mass": 92826.0, "gene_names": "Zfp780b-ps1", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D4A327", "url": "https://www.uniprot.org/uniprotkb/D4A327" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "D4A327", "url": "https://www.uniprot.org/uniprotkb/D4A327" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "D4A327", "url": "https://www.uniprot.org/uniprotkb/D4A327" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "D4A327", "url": "https://www.uniprot.org/uniprotkb/D4A327" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "D4A327", "url": "https://www.uniprot.org/uniprotkb/D4A327" } ], "pmid": "" }, { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "D4A327", "url": "https://www.uniprot.org/uniprotkb/D4A327" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D4A327-1" }, { "uniprot_canonical_ac": "D4A355-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4A355", "url": "https://www.uniprot.org/uniprotkb/D4A355" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 867, "chemical_mass": 96363.0, "gene_names": "Mastl;Mastl", "protein_name": "Serine/threonine-protein kinase greatwall", "disease": [ { "disease_id": "DOID:1588", "name": "thrombocytopenia", "description": "A blood platelet disease that is characterized by low a platelet count in the blood.", "url": "https://disease-ontology.org/term/DOID:1588", "evidence": [ { "id": "1588", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1588" } ], "weight": 0.0 } ], "biological_process": [ { "name": "female meiosis II", "id": "GO:0007147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007147", "evidence": [ { "database": "UniProtKB", "id": "D4A355", "url": "https://www.uniprot.org/uniprotkb/D4A355" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "D4A355", "url": "https://www.uniprot.org/uniprotkb/D4A355" } ], "pmid": "" }, { "name": "G2/M transition of mitotic cell cycle", "id": "GO:0000086", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000086", "evidence": [ { "database": "UniProtKB", "id": "D4A355", "url": "https://www.uniprot.org/uniprotkb/D4A355" } ], "pmid": "" }, { "name": "regulation of mitotic cell cycle", "id": "GO:0007346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007346", "evidence": [ { "database": "UniProtKB", "id": "D4A355", "url": "https://www.uniprot.org/uniprotkb/D4A355" } ], "pmid": "" }, { "name": "positive regulation of ubiquitin protein ligase activity", "id": "GO:1904668", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904668", "evidence": [ { "database": "UniProtKB", "id": "D4A355", "url": "https://www.uniprot.org/uniprotkb/D4A355" } ], "pmid": "" }, { "name": "meiotic spindle assembly", "id": "GO:0090306", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090306", "evidence": [ { "database": "UniProtKB", "id": "D4A355", "url": "https://www.uniprot.org/uniprotkb/D4A355" } ], "pmid": "" }, { "name": "meiotic chromosome condensation", "id": "GO:0010032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010032", "evidence": [ { "database": "UniProtKB", "id": "D4A355", "url": "https://www.uniprot.org/uniprotkb/D4A355" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "D4A355", "url": "https://www.uniprot.org/uniprotkb/D4A355" } ], "pmid": "" }, { "name": "positive regulation of meiotic cell cycle process involved in oocyte maturation", "id": "GO:1904146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904146", "evidence": [ { "database": "UniProtKB", "id": "D4A355", "url": "https://www.uniprot.org/uniprotkb/D4A355" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "D4A355", "url": "https://www.uniprot.org/uniprotkb/D4A355" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "D4A355", "url": "https://www.uniprot.org/uniprotkb/D4A355" } ], "pmid": "" }, { "name": "transmembrane transporter binding", "id": "GO:0044325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044325", "evidence": [ { "database": "UniProtKB", "id": "D4A355", "url": "https://www.uniprot.org/uniprotkb/D4A355" } ], "pmid": "" }, { "name": "kinase activity", "id": "GO:0016301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016301", "evidence": [ { "database": "UniProtKB", "id": "D4A355", "url": "https://www.uniprot.org/uniprotkb/D4A355" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D4A355", "url": "https://www.uniprot.org/uniprotkb/D4A355" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "D4A355", "url": "https://www.uniprot.org/uniprotkb/D4A355" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "D4A355", "url": "https://www.uniprot.org/uniprotkb/D4A355" } ], "pmid": "" }, { "name": "microtubule cytoskeleton", "id": "GO:0015630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015630", "evidence": [ { "database": "UniProtKB", "id": "D4A355", "url": "https://www.uniprot.org/uniprotkb/D4A355" } ], "pmid": "" }, { "name": "cleavage furrow", "id": "GO:0032154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032154", "evidence": [ { "database": "UniProtKB", "id": "D4A355", "url": "https://www.uniprot.org/uniprotkb/D4A355" } ], "pmid": "" }, { "name": "meiotic spindle", "id": "GO:0072687", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072687", "evidence": [ { "database": "UniProtKB", "id": "D4A355", "url": "https://www.uniprot.org/uniprotkb/D4A355" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "D4A355-1", "start_pos": "684", "end_pos": "684", "site_lbl": "Thr684", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 684, "start_aa": "Thr", "end_pos": 684, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr684", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "D4A355-1" }, { "uniprot_canonical_ac": "D4A3A9-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4A3A9", "url": "https://www.uniprot.org/uniprotkb/D4A3A9" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 674, "chemical_mass": 76098.0, "gene_names": "Galnt15;Galnt15;Galntl2", "protein_name": "Polypeptide N-acetylgalactosaminyltransferase", "disease": [], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "D4A3A9", "url": "https://www.uniprot.org/uniprotkb/D4A3A9" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "D4A3A9", "url": "https://www.uniprot.org/uniprotkb/D4A3A9" } ], "pmid": "" }, { "name": "transport vesicle", "id": "GO:0030133", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030133", "evidence": [ { "database": "UniProtKB", "id": "D4A3A9", "url": "https://www.uniprot.org/uniprotkb/D4A3A9" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "D4A3A9", "url": "https://www.uniprot.org/uniprotkb/D4A3A9" } ], "pmid": "" }, { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "D4A3A9", "url": "https://www.uniprot.org/uniprotkb/D4A3A9" } ], "pmid": "" }, { "name": "polypeptide N-acetylgalactosaminyltransferase activity", "id": "GO:0004653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004653", "evidence": [ { "database": "UniProtKB", "id": "D4A3A9", "url": "https://www.uniprot.org/uniprotkb/D4A3A9" } ], "pmid": "" } ], "biological_process": [ { "name": "protein O-linked glycosylation", "id": "GO:0006493", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006493", "evidence": [ { "database": "UniProtKB", "id": "D4A3A9", "url": "https://www.uniprot.org/uniprotkb/D4A3A9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D4A3A9-1" }, { "uniprot_canonical_ac": "D4A3E3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4A3E3", "url": "https://www.uniprot.org/uniprotkb/D4A3E3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 2291, "chemical_mass": 243395.0, "gene_names": "Arid1a;Arid1a", "protein_name": "", "disease": [ { "disease_id": "DOID:0050934", "name": "ovarian clear cell carcinoma", "description": "An ovarian carcinoma that has_material_basis_in cells with clear cytoplasm and glycogen secreting hob nail cells.", "url": "https://disease-ontology.org/term/DOID:0050934", "evidence": [ { "id": "0050934", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050934" } ], "weight": 0.0 }, { "disease_id": "DOID:0070042", "name": "Coffin-Siris syndrome 1", "description": "A Coffin-Siris syndrome that has_material_basis_in an autosomal dominant mutation of the ARID1B gene on chromosome 6q25.3.", "url": "https://disease-ontology.org/term/DOID:0070042", "evidence": [ { "id": "0070042", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070042" } ], "weight": 0.0 }, { "disease_id": "DOID:0070044", "name": "Coffin-Siris syndrome 2", "description": "A Coffin-Siris syndrome that has_material_basis_in an autosomal dominant mutation of the ARID1A gene on chromosome 1p36.11.", "url": "https://disease-ontology.org/term/DOID:0070044", "evidence": [ { "id": "0070044", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070044" } ], "weight": 0.0 }, { "disease_id": "DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ], "weight": 0.0 }, { "disease_id": "DOID:10591", "name": "pre-eclampsia", "description": "A hypertension occurring during pregnancy characterized by large amounts of protein in the urine (proteinuria) and edema, usually by the last trimester of pregnancy.", "url": "https://disease-ontology.org/term/DOID:10591", "evidence": [ { "id": "10591", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10591" } ], "weight": 0.0 }, { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 }, { "disease_id": "DOID:1925", "name": "Coffin-Siris syndrome", "description": "An autosomal dominant intellectual developmental disorder that is characterized by mental retardation associated with coarse facial features, hypertrichosis, sparse scalp hair, and hypoplastic or absent fifth fingernails or toenails.", "url": "https://disease-ontology.org/term/DOID:1925", "evidence": [ { "id": "1925", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1925" } ], "weight": 0.0 }, { "disease_id": "DOID:219", "name": "colon cancer", "description": "A colorectal cancer that is located_in the colon.", "url": "https://disease-ontology.org/term/DOID:219", "evidence": [ { "id": "219", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:219" } ], "weight": 0.0 }, { "disease_id": "DOID:2870", "name": "endometrial adenocarcinoma", "description": "An endometrial carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:2870", "evidence": [ { "id": "2870", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2870" } ], "weight": 0.0 }, { "disease_id": "DOID:3717", "name": "gastric adenocarcinoma", "description": "A stomach carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:3717", "evidence": [ { "id": "3717", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3717" } ], "weight": 0.0 }, { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 }, { "disease_id": "DOID:4914", "name": "esophagus adenocarcinoma", "description": "An esophageal carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:4914", "evidence": [ { "id": "4914", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4914" } ], "weight": 0.0 }, { "disease_id": "DOID:4927", "name": "Klatskin's tumor", "description": "An intrahepatic cholangiocarcinoma arising near or at the confluence of the right and left hepatic ducts.", "url": "https://disease-ontology.org/term/DOID:4927", "evidence": [ { "id": "4927", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4927" } ], "weight": 0.0 }, { "disease_id": "DOID:4928", "name": "intrahepatic cholangiocarcinoma", "description": "A cholangiocarcinoma that arises from the intrahepatic bile duct epithelium in any site of the intrahepatic biliary tree.", "url": "https://disease-ontology.org/term/DOID:4928", "evidence": [ { "id": "4928", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4928" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:769", "name": "neuroblastoma", "description": "An autonomic nervous system neoplasm that derives_from immature nerve cells.", "url": "https://disease-ontology.org/term/DOID:769", "evidence": [ { "id": "769", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:769" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 }, { "disease_id": "DOID:9261", "name": "nasopharynx carcinoma", "description": "A pharynx cancer that is located in the nasopharynx, the uppermost region of the pharynx or throat, where the nasal passages and auditory tubes join the remainder of the upper respiratory tract.", "url": "https://disease-ontology.org/term/DOID:9261", "evidence": [ { "id": "9261", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9261" } ], "weight": 0.0 } ], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "D4A3E3", "url": "https://www.uniprot.org/uniprotkb/D4A3E3" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "D4A3E3", "url": "https://www.uniprot.org/uniprotkb/D4A3E3" } ], "pmid": "" }, { "name": "forebrain development", "id": "GO:0030900", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030900", "evidence": [ { "database": "UniProtKB", "id": "D4A3E3", "url": "https://www.uniprot.org/uniprotkb/D4A3E3" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "D4A3E3", "url": "https://www.uniprot.org/uniprotkb/D4A3E3" } ], "pmid": "" }, { "name": "neural tube closure", "id": "GO:0001843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001843", "evidence": [ { "database": "UniProtKB", "id": "D4A3E3", "url": "https://www.uniprot.org/uniprotkb/D4A3E3" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "D4A3E3", "url": "https://www.uniprot.org/uniprotkb/D4A3E3" } ], "pmid": "" }, { "name": "stem cell population maintenance", "id": "GO:0019827", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019827", "evidence": [ { "database": "UniProtKB", "id": "D4A3E3", "url": "https://www.uniprot.org/uniprotkb/D4A3E3" } ], "pmid": "" }, { "name": "cardiac muscle cell differentiation", "id": "GO:0055007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055007", "evidence": [ { "database": "UniProtKB", "id": "D4A3E3", "url": "https://www.uniprot.org/uniprotkb/D4A3E3" } ], "pmid": "" }, { "name": "gastrulation", "id": "GO:0007369", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007369", "evidence": [ { "database": "UniProtKB", "id": "D4A3E3", "url": "https://www.uniprot.org/uniprotkb/D4A3E3" } ], "pmid": "" }, { "name": "formation of primary germ layer", "id": "GO:0001704", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001704", "evidence": [ { "database": "UniProtKB", "id": "D4A3E3", "url": "https://www.uniprot.org/uniprotkb/D4A3E3" } ], "pmid": "" }, { "name": "cardiac chamber development", "id": "GO:0003205", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003205", "evidence": [ { "database": "UniProtKB", "id": "D4A3E3", "url": "https://www.uniprot.org/uniprotkb/D4A3E3" } ], "pmid": "" }, { "name": "optic cup formation involved in camera-type eye development", "id": "GO:0003408", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003408", "evidence": [ { "database": "UniProtKB", "id": "D4A3E3", "url": "https://www.uniprot.org/uniprotkb/D4A3E3" } ], "pmid": "" }, { "name": "nucleosome disassembly", "id": "GO:0006337", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006337", "evidence": [ { "database": "UniProtKB", "id": "D4A3E3", "url": "https://www.uniprot.org/uniprotkb/D4A3E3" } ], "pmid": "" }, { "name": "embryo implantation", "id": "GO:0007566", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007566", "evidence": [ { "database": "UniProtKB", "id": "D4A3E3", "url": "https://www.uniprot.org/uniprotkb/D4A3E3" } ], "pmid": "" }, { "name": "placenta blood vessel development", "id": "GO:0060674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060674", "evidence": [ { "database": "UniProtKB", "id": "D4A3E3", "url": "https://www.uniprot.org/uniprotkb/D4A3E3" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "D4A3E3", "url": "https://www.uniprot.org/uniprotkb/D4A3E3" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "D4A3E3", "url": "https://www.uniprot.org/uniprotkb/D4A3E3" } ], "pmid": "" }, { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "D4A3E3", "url": "https://www.uniprot.org/uniprotkb/D4A3E3" } ], "pmid": "" }, { "name": "nuclear receptor binding", "id": "GO:0016922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016922", "evidence": [ { "database": "UniProtKB", "id": "D4A3E3", "url": "https://www.uniprot.org/uniprotkb/D4A3E3" } ], "pmid": "" }, { "name": "ATP-dependent chromatin remodeler activity", "id": "GO:0140658", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140658", "evidence": [ { "database": "UniProtKB", "id": "D4A3E3", "url": "https://www.uniprot.org/uniprotkb/D4A3E3" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "D4A3E3", "url": "https://www.uniprot.org/uniprotkb/D4A3E3" } ], "pmid": "" }, { "name": "SWI/SNF complex", "id": "GO:0016514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016514", "evidence": [ { "database": "UniProtKB", "id": "D4A3E3", "url": "https://www.uniprot.org/uniprotkb/D4A3E3" } ], "pmid": "" }, { "name": "npBAF complex", "id": "GO:0071564", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071564", "evidence": [ { "database": "UniProtKB", "id": "D4A3E3", "url": "https://www.uniprot.org/uniprotkb/D4A3E3" } ], "pmid": "" }, { "name": "nBAF complex", "id": "GO:0071565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071565", "evidence": [ { "database": "UniProtKB", "id": "D4A3E3", "url": "https://www.uniprot.org/uniprotkb/D4A3E3" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "D4A3E3", "url": "https://www.uniprot.org/uniprotkb/D4A3E3" } ], "pmid": "" }, { "name": "brahma complex", "id": "GO:0035060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035060", "evidence": [ { "database": "UniProtKB", "id": "D4A3E3", "url": "https://www.uniprot.org/uniprotkb/D4A3E3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D4A3E3-1" }, { "uniprot_canonical_ac": "D4A3H3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4A3H3", "url": "https://www.uniprot.org/uniprotkb/D4A3H3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 288, "chemical_mass": 31642.0, "gene_names": "Creg2;Creg2", "protein_name": "", "disease": [], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "D4A3H3", "url": "https://www.uniprot.org/uniprotkb/D4A3H3" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "D4A3H3", "url": "https://www.uniprot.org/uniprotkb/D4A3H3" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "D4A3H3", "url": "https://www.uniprot.org/uniprotkb/D4A3H3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D4A3H3-1" }, { "uniprot_canonical_ac": "D4A3I0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4A3I0", "url": "https://www.uniprot.org/uniprotkb/D4A3I0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 734, "chemical_mass": 84106.0, "gene_names": "Zranb1;LOC100360606;Zranb1", "protein_name": "Ubiquitin thioesterase ZRANB1", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D4A3I0", "url": "https://www.uniprot.org/uniprotkb/D4A3I0" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "D4A3I0", "url": "https://www.uniprot.org/uniprotkb/D4A3I0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "D4A3I0", "url": "https://www.uniprot.org/uniprotkb/D4A3I0" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "D4A3I0", "url": "https://www.uniprot.org/uniprotkb/D4A3I0" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "D4A3I0", "url": "https://www.uniprot.org/uniprotkb/D4A3I0" } ], "pmid": "" }, { "name": "polyubiquitin modification-dependent protein binding", "id": "GO:0031593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031593", "evidence": [ { "database": "UniProtKB", "id": "D4A3I0", "url": "https://www.uniprot.org/uniprotkb/D4A3I0" } ], "pmid": "" }, { "name": "K63-linked polyubiquitin modification-dependent protein binding", "id": "GO:0070530", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070530", "evidence": [ { "database": "UniProtKB", "id": "D4A3I0", "url": "https://www.uniprot.org/uniprotkb/D4A3I0" } ], "pmid": "" }, { "name": "cysteine-type deubiquitinase activity", "id": "GO:0004843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004843", "evidence": [ { "database": "UniProtKB", "id": "D4A3I0", "url": "https://www.uniprot.org/uniprotkb/D4A3I0" } ], "pmid": "" }, { "name": "deubiquitinase activity", "id": "GO:0101005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0101005", "evidence": [ { "database": "UniProtKB", "id": "D4A3I0", "url": "https://www.uniprot.org/uniprotkb/D4A3I0" } ], "pmid": "" } ], "biological_process": [ { "name": "protein deubiquitination", "id": "GO:0016579", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016579", "evidence": [ { "database": "UniProtKB", "id": "D4A3I0", "url": "https://www.uniprot.org/uniprotkb/D4A3I0" } ], "pmid": "" }, { "name": "protein K63-linked deubiquitination", "id": "GO:0070536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070536", "evidence": [ { "database": "UniProtKB", "id": "D4A3I0", "url": "https://www.uniprot.org/uniprotkb/D4A3I0" } ], "pmid": "" }, { "name": "Wnt signaling pathway", "id": "GO:0016055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055", "evidence": [ { "database": "UniProtKB", "id": "D4A3I0", "url": "https://www.uniprot.org/uniprotkb/D4A3I0" } ], "pmid": "" }, { "name": "positive regulation of canonical Wnt signaling pathway", "id": "GO:0090263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090263", "evidence": [ { "database": "UniProtKB", "id": "D4A3I0", "url": "https://www.uniprot.org/uniprotkb/D4A3I0" } ], "pmid": "" }, { "name": "positive regulation of Wnt signaling pathway", "id": "GO:0030177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030177", "evidence": [ { "database": "UniProtKB", "id": "D4A3I0", "url": "https://www.uniprot.org/uniprotkb/D4A3I0" } ], "pmid": "" }, { "name": "protein K29-linked deubiquitination", "id": "GO:0035523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035523", "evidence": [ { "database": "UniProtKB", "id": "D4A3I0", "url": "https://www.uniprot.org/uniprotkb/D4A3I0" } ], "pmid": "" }, { "name": "protein K33-linked deubiquitination", "id": "GO:1990168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990168", "evidence": [ { "database": "UniProtKB", "id": "D4A3I0", "url": "https://www.uniprot.org/uniprotkb/D4A3I0" } ], "pmid": "" }, { "name": "protein deubiquitination involved in ubiquitin-dependent protein catabolic process", "id": "GO:0071947", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071947", "evidence": [ { "database": "UniProtKB", "id": "D4A3I0", "url": "https://www.uniprot.org/uniprotkb/D4A3I0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D4A3I0-1" }, { "uniprot_canonical_ac": "D4A3J0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4A3J0", "url": "https://www.uniprot.org/uniprotkb/D4A3J0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1206, "chemical_mass": 133629.0, "gene_names": "Spata31g1;LOC100360821;Spata31g1", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "D4A3J0-1", "start_pos": "253", "end_pos": "253", "site_lbl": "Thr253", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 253, "start_aa": "Thr", "end_pos": 253, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr253", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "D4A3J0-1" }, { "uniprot_canonical_ac": "D4A3V4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4A3V4", "url": "https://www.uniprot.org/uniprotkb/D4A3V4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 703, "chemical_mass": 77723.0, "gene_names": "Rnf214;Rnf214", "protein_name": "", "disease": [], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "D4A3V4", "url": "https://www.uniprot.org/uniprotkb/D4A3V4" } ], "pmid": "" }, { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "D4A3V4", "url": "https://www.uniprot.org/uniprotkb/D4A3V4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D4A3V4-1" }, { "uniprot_canonical_ac": "D4A3Y5-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4A3Y5", "url": "https://www.uniprot.org/uniprotkb/D4A3Y5" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 346, "chemical_mass": 38771.0, "gene_names": "Tmem236;LOC100364134;Tmem236", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D4A3Y5-1" }, { "uniprot_canonical_ac": "D4A454-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4A454", "url": "https://www.uniprot.org/uniprotkb/D4A454" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 996, "chemical_mass": 109188.0, "gene_names": "Map3k21;Map3k21;Mlk4;RGD1306091", "protein_name": "Mitogen-activated protein kinase kinase kinase", "disease": [], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "D4A454", "url": "https://www.uniprot.org/uniprotkb/D4A454" } ], "pmid": "" }, { "name": "JUN kinase kinase kinase activity", "id": "GO:0004706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004706", "evidence": [ { "database": "UniProtKB", "id": "D4A454", "url": "https://www.uniprot.org/uniprotkb/D4A454" } ], "pmid": "" }, { "name": "protein serine kinase activity", "id": "GO:0106310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106310", "evidence": [ { "database": "UniProtKB", "id": "D4A454", "url": "https://www.uniprot.org/uniprotkb/D4A454" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "D4A454", "url": "https://www.uniprot.org/uniprotkb/D4A454" } ], "pmid": "" } ], "biological_process": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "D4A454", "url": "https://www.uniprot.org/uniprotkb/D4A454" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D4A454-1" }, { "uniprot_canonical_ac": "D4A4A0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4A4A0", "url": "https://www.uniprot.org/uniprotkb/D4A4A0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 322, "chemical_mass": 35931.0, "gene_names": "Or14j6;Olr1692;Or14j6", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "D4A4A0", "url": "https://www.uniprot.org/uniprotkb/D4A4A0" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "D4A4A0", "url": "https://www.uniprot.org/uniprotkb/D4A4A0" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "D4A4A0", "url": "https://www.uniprot.org/uniprotkb/D4A4A0" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "D4A4A0", "url": "https://www.uniprot.org/uniprotkb/D4A4A0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D4A4A0-1" }, { "uniprot_canonical_ac": "D4A4E6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4A4E6", "url": "https://www.uniprot.org/uniprotkb/D4A4E6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 471, "chemical_mass": 52480.0, "gene_names": "Nalf2;Fam155b;Nalf2;Tmem28l", "protein_name": "", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "D4A4E6", "url": "https://www.uniprot.org/uniprotkb/D4A4E6" } ], "pmid": "" } ], "biological_process": [ { "name": "calcium ion import across plasma membrane", "id": "GO:0098703", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098703", "evidence": [ { "database": "UniProtKB", "id": "D4A4E6", "url": "https://www.uniprot.org/uniprotkb/D4A4E6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D4A4E6-1" }, { "uniprot_canonical_ac": "D4A4L1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4A4L1", "url": "https://www.uniprot.org/uniprotkb/D4A4L1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 357, "chemical_mass": 38026.0, "gene_names": "Sohlh1", "protein_name": "", "disease": [ { "disease_id": "DOID:0080497", "name": "ovarian dysgenesis 5", "description": "A 46 XX gonadal dysgenesis that has_material_basis_in homozygous mutation in the SOHLH1 gene on chromosome 9q34.", "url": "https://disease-ontology.org/term/DOID:0080497", "evidence": [ { "id": "0080497", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080497" } ], "weight": 0.0 }, { "disease_id": "DOID:0111925", "name": "spermatogenic failure 32", "description": "A spermatogenic failure characterized by nonobstructive azoospermia, absence of spermatogenic cells and a Sertoli cell-only phenotype in testes that has_material_basis_in heterozygous mutation in the SOHLH1 gene on chromosome 9q34.3.", "url": "https://disease-ontology.org/term/DOID:0111925", "evidence": [ { "id": "0111925", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111925" } ], "weight": 0.0 } ], "biological_process": [ { "name": "oocyte differentiation", "id": "GO:0009994", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009994", "evidence": [ { "database": "UniProtKB", "id": "D4A4L1", "url": "https://www.uniprot.org/uniprotkb/D4A4L1" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "D4A4L1", "url": "https://www.uniprot.org/uniprotkb/D4A4L1" } ], "pmid": "" }, { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "D4A4L1", "url": "https://www.uniprot.org/uniprotkb/D4A4L1" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "D4A4L1", "url": "https://www.uniprot.org/uniprotkb/D4A4L1" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "D4A4L1", "url": "https://www.uniprot.org/uniprotkb/D4A4L1" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "D4A4L1", "url": "https://www.uniprot.org/uniprotkb/D4A4L1" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "D4A4L1", "url": "https://www.uniprot.org/uniprotkb/D4A4L1" } ], "pmid": "" }, { "name": "ovarian follicle development", "id": "GO:0001541", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001541", "evidence": [ { "database": "UniProtKB", "id": "D4A4L1", "url": "https://www.uniprot.org/uniprotkb/D4A4L1" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "D4A4L1", "url": "https://www.uniprot.org/uniprotkb/D4A4L1" } ], "pmid": "" }, { "name": "oogenesis", "id": "GO:0048477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048477", "evidence": [ { "database": "UniProtKB", "id": "D4A4L1", "url": "https://www.uniprot.org/uniprotkb/D4A4L1" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "D4A4L1", "url": "https://www.uniprot.org/uniprotkb/D4A4L1" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "D4A4L1", "url": "https://www.uniprot.org/uniprotkb/D4A4L1" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "D4A4L1", "url": "https://www.uniprot.org/uniprotkb/D4A4L1" } ], "pmid": "" }, { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "D4A4L1", "url": "https://www.uniprot.org/uniprotkb/D4A4L1" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "D4A4L1", "url": "https://www.uniprot.org/uniprotkb/D4A4L1" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "D4A4L1", "url": "https://www.uniprot.org/uniprotkb/D4A4L1" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "D4A4L1", "url": "https://www.uniprot.org/uniprotkb/D4A4L1" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "D4A4L1", "url": "https://www.uniprot.org/uniprotkb/D4A4L1" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D4A4L1", "url": "https://www.uniprot.org/uniprotkb/D4A4L1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "D4A4L1", "url": "https://www.uniprot.org/uniprotkb/D4A4L1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D4A4L1-1" }, { "uniprot_canonical_ac": "D4A548-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4A548", "url": "https://www.uniprot.org/uniprotkb/D4A548" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 567, "chemical_mass": 63761.0, "gene_names": "Armcx5;Armcx5;LOC102552920", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "D4A548-1", "start_pos": "68", "end_pos": "68", "site_lbl": "Thr68", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 68, "start_aa": "Thr", "end_pos": 68, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr68", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "D4A548-1" }, { "uniprot_canonical_ac": "D4A5R3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4A5R3", "url": "https://www.uniprot.org/uniprotkb/D4A5R3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1592, "chemical_mass": 168176.0, "gene_names": "Ahdc1;Ahdc1;RGD1310031", "protein_name": "", "disease": [ { "disease_id": "DOID:0070055", "name": "Xia-Gibbs Syndrome", "description": "An autosomal dominant intellectual developmental disorder that has_material_basis_in an autosomal dominant mutation of the AHDC1 gene on chromosome 1p36.1-p35.3.", "url": "https://disease-ontology.org/term/DOID:0070055", "evidence": [ { "id": "0070055", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070055" } ], "weight": 0.0 } ], "biological_process": [ { "name": "glycolipid metabolic process", "id": "GO:0006664", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006664", "evidence": [ { "database": "UniProtKB", "id": "D4A5R3", "url": "https://www.uniprot.org/uniprotkb/D4A5R3" } ], "pmid": "" }, { "name": "liver development", "id": "GO:0001889", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001889", "evidence": [ { "database": "UniProtKB", "id": "D4A5R3", "url": "https://www.uniprot.org/uniprotkb/D4A5R3" } ], "pmid": "" }, { "name": "adipose tissue development", "id": "GO:0060612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060612", "evidence": [ { "database": "UniProtKB", "id": "D4A5R3", "url": "https://www.uniprot.org/uniprotkb/D4A5R3" } ], "pmid": "" }, { "name": "response to insulin", "id": "GO:0032868", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032868", "evidence": [ { "database": "UniProtKB", "id": "D4A5R3", "url": "https://www.uniprot.org/uniprotkb/D4A5R3" } ], "pmid": "" }, { "name": "energy reserve metabolic process", "id": "GO:0006112", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006112", "evidence": [ { "database": "UniProtKB", "id": "D4A5R3", "url": "https://www.uniprot.org/uniprotkb/D4A5R3" } ], "pmid": "" }, { "name": "mesoderm formation", "id": "GO:0001707", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001707", "evidence": [ { "database": "UniProtKB", "id": "D4A5R3", "url": "https://www.uniprot.org/uniprotkb/D4A5R3" } ], "pmid": "" }, { "name": "hormone metabolic process", "id": "GO:0042445", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042445", "evidence": [ { "database": "UniProtKB", "id": "D4A5R3", "url": "https://www.uniprot.org/uniprotkb/D4A5R3" } ], "pmid": "" }, { "name": "skin morphogenesis", "id": "GO:0043589", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043589", "evidence": [ { "database": "UniProtKB", "id": "D4A5R3", "url": "https://www.uniprot.org/uniprotkb/D4A5R3" } ], "pmid": "" }, { "name": "aerobic respiration", "id": "GO:0009060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009060", "evidence": [ { "database": "UniProtKB", "id": "D4A5R3", "url": "https://www.uniprot.org/uniprotkb/D4A5R3" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "D4A5R3", "url": "https://www.uniprot.org/uniprotkb/D4A5R3" } ], "pmid": "" }, { "name": "promoter-enhancer loop anchoring activity", "id": "GO:0140585", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140585", "evidence": [ { "database": "UniProtKB", "id": "D4A5R3", "url": "https://www.uniprot.org/uniprotkb/D4A5R3" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D4A5R3", "url": "https://www.uniprot.org/uniprotkb/D4A5R3" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "D4A5R3", "url": "https://www.uniprot.org/uniprotkb/D4A5R3" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "D4A5R3", "url": "https://www.uniprot.org/uniprotkb/D4A5R3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "D4A5R3-1", "start_pos": "1020", "end_pos": "1020", "site_lbl": "Thr1020", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1020, "start_aa": "Thr", "end_pos": 1020, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1020", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "D4A5R3-1", "start_pos": "34", "end_pos": "34", "site_lbl": "Thr34", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 34, "start_aa": "Thr", "end_pos": 34, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr34", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "D4A5R3-1", "start_pos": "571", "end_pos": "571", "site_lbl": "Thr571", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 571, "start_aa": "Thr", "end_pos": 571, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr571", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "D4A5R3-1" }, { "uniprot_canonical_ac": "D4A690-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4A690", "url": "https://www.uniprot.org/uniprotkb/D4A690" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 285, "chemical_mass": 32063.0, "gene_names": "Birc7;Birc7;RGD1562883", "protein_name": "RING-type E3 ubiquitin transferase", "disease": [ { "disease_id": "DOID:0050860", "name": "colorectal adenoma", "description": "An intestinal benign neoplasm that has_material_basis_in epithelial tissue of glandular origin and is located_in colon and located_in rectum.", "url": "https://disease-ontology.org/term/DOID:0050860", "evidence": [ { "id": "0050860", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050860" } ], "weight": 0.0 }, { "disease_id": "DOID:0050861", "name": "colorectal adenocarcinoma", "description": "A colorectal carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:0050861", "evidence": [ { "id": "0050861", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050861" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D4A690", "url": "https://www.uniprot.org/uniprotkb/D4A690" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "D4A690", "url": "https://www.uniprot.org/uniprotkb/D4A690" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "D4A690", "url": "https://www.uniprot.org/uniprotkb/D4A690" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "D4A690", "url": "https://www.uniprot.org/uniprotkb/D4A690" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "D4A690", "url": "https://www.uniprot.org/uniprotkb/D4A690" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "D4A690", "url": "https://www.uniprot.org/uniprotkb/D4A690" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "D4A690", "url": "https://www.uniprot.org/uniprotkb/D4A690" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "D4A690", "url": "https://www.uniprot.org/uniprotkb/D4A690" } ], "pmid": "" }, { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "D4A690", "url": "https://www.uniprot.org/uniprotkb/D4A690" } ], "pmid": "" }, { "name": "cysteine-type endopeptidase inhibitor activity involved in apoptotic process", "id": "GO:0043027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043027", "evidence": [ { "database": "UniProtKB", "id": "D4A690", "url": "https://www.uniprot.org/uniprotkb/D4A690" } ], "pmid": "" }, { "name": "cysteine-type endopeptidase inhibitor activity", "id": "GO:0004869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004869", "evidence": [ { "database": "UniProtKB", "id": "D4A690", "url": "https://www.uniprot.org/uniprotkb/D4A690" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of cell population proliferation", "id": "GO:0042127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042127", "evidence": [ { "database": "UniProtKB", "id": "D4A690", "url": "https://www.uniprot.org/uniprotkb/D4A690" } ], "pmid": "" }, { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "D4A690", "url": "https://www.uniprot.org/uniprotkb/D4A690" } ], "pmid": "" }, { "name": "positive regulation of JNK cascade", "id": "GO:0046330", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046330", "evidence": [ { "database": "UniProtKB", "id": "D4A690", "url": "https://www.uniprot.org/uniprotkb/D4A690" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "D4A690", "url": "https://www.uniprot.org/uniprotkb/D4A690" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "D4A690", "url": "https://www.uniprot.org/uniprotkb/D4A690" } ], "pmid": "" }, { "name": "positive regulation of protein ubiquitination", "id": "GO:0031398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031398", "evidence": [ { "database": "UniProtKB", "id": "D4A690", "url": "https://www.uniprot.org/uniprotkb/D4A690" } ], "pmid": "" }, { "name": "regulation of apoptotic process", "id": "GO:0042981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042981", "evidence": [ { "database": "UniProtKB", "id": "D4A690", "url": "https://www.uniprot.org/uniprotkb/D4A690" } ], "pmid": "" }, { "name": "negative regulation of tumor necrosis factor-mediated signaling pathway", "id": "GO:0010804", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010804", "evidence": [ { "database": "UniProtKB", "id": "D4A690", "url": "https://www.uniprot.org/uniprotkb/D4A690" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "D4A690", "url": "https://www.uniprot.org/uniprotkb/D4A690" } ], "pmid": "" }, { "name": "regulation of natural killer cell apoptotic process", "id": "GO:0070247", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070247", "evidence": [ { "database": "UniProtKB", "id": "D4A690", "url": "https://www.uniprot.org/uniprotkb/D4A690" } ], "pmid": "" }, { "name": "lens development in camera-type eye", "id": "GO:0002088", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002088", "evidence": [ { "database": "UniProtKB", "id": "D4A690", "url": "https://www.uniprot.org/uniprotkb/D4A690" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "D4A690-1", "start_pos": "195", "end_pos": "195", "site_lbl": "Thr195", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 195, "start_aa": "Thr", "end_pos": 195, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr195", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "D4A690-1" }, { "uniprot_canonical_ac": "D4A6B3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4A6B3", "url": "https://www.uniprot.org/uniprotkb/D4A6B3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 343, "chemical_mass": 38497.0, "gene_names": "Slamf6;RGD1561848;Slamf6", "protein_name": "", "disease": [], "biological_process": [ { "name": "natural killer cell differentiation", "id": "GO:0001779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001779", "evidence": [ { "database": "UniProtKB", "id": "D4A6B3", "url": "https://www.uniprot.org/uniprotkb/D4A6B3" } ], "pmid": "" }, { "name": "positive regulation of interleukin-17 production", "id": "GO:0032740", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032740", "evidence": [ { "database": "UniProtKB", "id": "D4A6B3", "url": "https://www.uniprot.org/uniprotkb/D4A6B3" } ], "pmid": "" }, { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "D4A6B3", "url": "https://www.uniprot.org/uniprotkb/D4A6B3" } ], "pmid": "" }, { "name": "T cell activation", "id": "GO:0042110", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042110", "evidence": [ { "database": "UniProtKB", "id": "D4A6B3", "url": "https://www.uniprot.org/uniprotkb/D4A6B3" } ], "pmid": "" }, { "name": "positive regulation of type II interferon production", "id": "GO:0032729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032729", "evidence": [ { "database": "UniProtKB", "id": "D4A6B3", "url": "https://www.uniprot.org/uniprotkb/D4A6B3" } ], "pmid": "" }, { "name": "positive regulation of natural killer cell mediated cytotoxicity", "id": "GO:0045954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045954", "evidence": [ { "database": "UniProtKB", "id": "D4A6B3", "url": "https://www.uniprot.org/uniprotkb/D4A6B3" } ], "pmid": "" }, { "name": "T-helper 17 cell lineage commitment", "id": "GO:0072540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072540", "evidence": [ { "database": "UniProtKB", "id": "D4A6B3", "url": "https://www.uniprot.org/uniprotkb/D4A6B3" } ], "pmid": "" }, { "name": "natural killer cell proliferation", "id": "GO:0001787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001787", "evidence": [ { "database": "UniProtKB", "id": "D4A6B3", "url": "https://www.uniprot.org/uniprotkb/D4A6B3" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "D4A6B3", "url": "https://www.uniprot.org/uniprotkb/D4A6B3" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "D4A6B3", "url": "https://www.uniprot.org/uniprotkb/D4A6B3" } ], "pmid": "" } ], "molecular_function": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "D4A6B3", "url": "https://www.uniprot.org/uniprotkb/D4A6B3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D4A6B3-1" }, { "uniprot_canonical_ac": "D4A6N8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4A6N8", "url": "https://www.uniprot.org/uniprotkb/D4A6N8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 681, "chemical_mass": 73910.0, "gene_names": "Tbr1;Tbr1", "protein_name": "", "disease": [ { "disease_id": "DOID:0060041", "name": "autism spectrum disorder", "description": "A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior.", "url": "https://disease-ontology.org/term/DOID:0060041", "evidence": [ { "id": "0060041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060041" } ], "weight": 0.0 } ], "biological_process": [ { "name": "cell fate specification", "id": "GO:0001708", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001708", "evidence": [ { "database": "UniProtKB", "id": "D4A6N8", "url": "https://www.uniprot.org/uniprotkb/D4A6N8" } ], "pmid": "" }, { "name": "specification of animal organ identity", "id": "GO:0010092", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010092", "evidence": [ { "database": "UniProtKB", "id": "D4A6N8", "url": "https://www.uniprot.org/uniprotkb/D4A6N8" } ], "pmid": "" }, { "name": "regulation of axon guidance", "id": "GO:1902667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902667", "evidence": [ { "database": "UniProtKB", "id": "D4A6N8", "url": "https://www.uniprot.org/uniprotkb/D4A6N8" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "D4A6N8", "url": "https://www.uniprot.org/uniprotkb/D4A6N8" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "D4A6N8", "url": "https://www.uniprot.org/uniprotkb/D4A6N8" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "D4A6N8", "url": "https://www.uniprot.org/uniprotkb/D4A6N8" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "D4A6N8", "url": "https://www.uniprot.org/uniprotkb/D4A6N8" } ], "pmid": "" }, { "name": "cerebral cortex development", "id": "GO:0021987", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021987", "evidence": [ { "database": "UniProtKB", "id": "D4A6N8", "url": "https://www.uniprot.org/uniprotkb/D4A6N8" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "D4A6N8", "url": "https://www.uniprot.org/uniprotkb/D4A6N8" } ], "pmid": "" }, { "name": "neuron differentiation", "id": "GO:0030182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030182", "evidence": [ { "database": "UniProtKB", "id": "D4A6N8", "url": "https://www.uniprot.org/uniprotkb/D4A6N8" } ], "pmid": "" }, { "name": "hindbrain development", "id": "GO:0030902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030902", "evidence": [ { "database": "UniProtKB", "id": "D4A6N8", "url": "https://www.uniprot.org/uniprotkb/D4A6N8" } ], "pmid": "" }, { "name": "conditioned taste aversion", "id": "GO:0001661", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001661", "evidence": [ { "database": "UniProtKB", "id": "D4A6N8", "url": "https://www.uniprot.org/uniprotkb/D4A6N8" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "D4A6N8", "url": "https://www.uniprot.org/uniprotkb/D4A6N8" } ], "pmid": "" }, { "name": "regulation of neuron projection development", "id": "GO:0010975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010975", "evidence": [ { "database": "UniProtKB", "id": "D4A6N8", "url": "https://www.uniprot.org/uniprotkb/D4A6N8" } ], "pmid": "" }, { "name": "commitment of neuronal cell to specific neuron type in forebrain", "id": "GO:0021902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021902", "evidence": [ { "database": "UniProtKB", "id": "D4A6N8", "url": "https://www.uniprot.org/uniprotkb/D4A6N8" } ], "pmid": "" }, { "name": "gene expression", "id": "GO:0010467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010467", "evidence": [ { "database": "UniProtKB", "id": "D4A6N8", "url": "https://www.uniprot.org/uniprotkb/D4A6N8" } ], "pmid": "" }, { "name": "amygdala development", "id": "GO:0021764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021764", "evidence": [ { "database": "UniProtKB", "id": "D4A6N8", "url": "https://www.uniprot.org/uniprotkb/D4A6N8" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "D4A6N8", "url": "https://www.uniprot.org/uniprotkb/D4A6N8" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "D4A6N8", "url": "https://www.uniprot.org/uniprotkb/D4A6N8" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "D4A6N8", "url": "https://www.uniprot.org/uniprotkb/D4A6N8" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "D4A6N8", "url": "https://www.uniprot.org/uniprotkb/D4A6N8" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "D4A6N8", "url": "https://www.uniprot.org/uniprotkb/D4A6N8" } ], "pmid": "" }, { "name": "chromatin DNA binding", "id": "GO:0031490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031490", "evidence": [ { "database": "UniProtKB", "id": "D4A6N8", "url": "https://www.uniprot.org/uniprotkb/D4A6N8" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D4A6N8", "url": "https://www.uniprot.org/uniprotkb/D4A6N8" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "D4A6N8", "url": "https://www.uniprot.org/uniprotkb/D4A6N8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "D4A6N8-1", "start_pos": "487", "end_pos": "487", "site_lbl": "Thr487", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 487, "start_aa": "Thr", "end_pos": 487, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr487", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "D4A6N8-1" }, { "uniprot_canonical_ac": "D4A6Q6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4A6Q6", "url": "https://www.uniprot.org/uniprotkb/D4A6Q6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1559, "chemical_mass": 176645.0, "gene_names": "Ino80;Ino80;Inoc1;RGD1310969", "protein_name": "Chromatin-remodeling ATPase INO80", "disease": [], "biological_process": [ { "name": "regulation of DNA strand elongation", "id": "GO:0060382", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060382", "evidence": [ { "database": "UniProtKB", "id": "D4A6Q6", "url": "https://www.uniprot.org/uniprotkb/D4A6Q6" } ], "pmid": "" }, { "name": "regulation of chromosome organization", "id": "GO:0033044", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033044", "evidence": [ { "database": "UniProtKB", "id": "D4A6Q6", "url": "https://www.uniprot.org/uniprotkb/D4A6Q6" } ], "pmid": "" }, { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "D4A6Q6", "url": "https://www.uniprot.org/uniprotkb/D4A6Q6" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "D4A6Q6", "url": "https://www.uniprot.org/uniprotkb/D4A6Q6" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "D4A6Q6", "url": "https://www.uniprot.org/uniprotkb/D4A6Q6" } ], "pmid": "" }, { "name": "positive regulation of cell growth", "id": "GO:0030307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030307", "evidence": [ { "database": "UniProtKB", "id": "D4A6Q6", "url": "https://www.uniprot.org/uniprotkb/D4A6Q6" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "D4A6Q6", "url": "https://www.uniprot.org/uniprotkb/D4A6Q6" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "D4A6Q6", "url": "https://www.uniprot.org/uniprotkb/D4A6Q6" } ], "pmid": "" }, { "name": "telomere maintenance", "id": "GO:0000723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000723", "evidence": [ { "database": "UniProtKB", "id": "D4A6Q6", "url": "https://www.uniprot.org/uniprotkb/D4A6Q6" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "D4A6Q6", "url": "https://www.uniprot.org/uniprotkb/D4A6Q6" } ], "pmid": "" }, { "name": "double-strand break repair", "id": "GO:0006302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006302", "evidence": [ { "database": "UniProtKB", "id": "D4A6Q6", "url": "https://www.uniprot.org/uniprotkb/D4A6Q6" } ], "pmid": "" }, { "name": "positive regulation of DNA repair", "id": "GO:0045739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045739", "evidence": [ { "database": "UniProtKB", "id": "D4A6Q6", "url": "https://www.uniprot.org/uniprotkb/D4A6Q6" } ], "pmid": "" }, { "name": "regulation of DNA replication", "id": "GO:0006275", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006275", "evidence": [ { "database": "UniProtKB", "id": "D4A6Q6", "url": "https://www.uniprot.org/uniprotkb/D4A6Q6" } ], "pmid": "" }, { "name": "double-strand break repair via homologous recombination", "id": "GO:0000724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000724", "evidence": [ { "database": "UniProtKB", "id": "D4A6Q6", "url": "https://www.uniprot.org/uniprotkb/D4A6Q6" } ], "pmid": "" }, { "name": "cellular response to UV", "id": "GO:0034644", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034644", "evidence": [ { "database": "UniProtKB", "id": "D4A6Q6", "url": "https://www.uniprot.org/uniprotkb/D4A6Q6" } ], "pmid": "" }, { "name": "UV-damage excision repair", "id": "GO:0070914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070914", "evidence": [ { "database": "UniProtKB", "id": "D4A6Q6", "url": "https://www.uniprot.org/uniprotkb/D4A6Q6" } ], "pmid": "" }, { "name": "cellular response to ionizing radiation", "id": "GO:0071479", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071479", "evidence": [ { "database": "UniProtKB", "id": "D4A6Q6", "url": "https://www.uniprot.org/uniprotkb/D4A6Q6" } ], "pmid": "" }, { "name": "spindle assembly", "id": "GO:0051225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051225", "evidence": [ { "database": "UniProtKB", "id": "D4A6Q6", "url": "https://www.uniprot.org/uniprotkb/D4A6Q6" } ], "pmid": "" }, { "name": "mitotic sister chromatid segregation", "id": "GO:0000070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000070", "evidence": [ { "database": "UniProtKB", "id": "D4A6Q6", "url": "https://www.uniprot.org/uniprotkb/D4A6Q6" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "D4A6Q6", "url": "https://www.uniprot.org/uniprotkb/D4A6Q6" } ], "pmid": "" }, { "name": "regulation of G1/S transition of mitotic cell cycle", "id": "GO:2000045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000045", "evidence": [ { "database": "UniProtKB", "id": "D4A6Q6", "url": "https://www.uniprot.org/uniprotkb/D4A6Q6" } ], "pmid": "" }, { "name": "positive regulation of nuclear cell cycle DNA replication", "id": "GO:0010571", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010571", "evidence": [ { "database": "UniProtKB", "id": "D4A6Q6", "url": "https://www.uniprot.org/uniprotkb/D4A6Q6" } ], "pmid": "" }, { "name": "regulation of embryonic development", "id": "GO:0045995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045995", "evidence": [ { "database": "UniProtKB", "id": "D4A6Q6", "url": "https://www.uniprot.org/uniprotkb/D4A6Q6" } ], "pmid": "" }, { "name": "regulation of DNA repair", "id": "GO:0006282", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006282", "evidence": [ { "database": "UniProtKB", "id": "D4A6Q6", "url": "https://www.uniprot.org/uniprotkb/D4A6Q6" } ], "pmid": "" }, { "name": "positive regulation of telomere maintenance in response to DNA damage", "id": "GO:1904507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904507", "evidence": [ { "database": "UniProtKB", "id": "D4A6Q6", "url": "https://www.uniprot.org/uniprotkb/D4A6Q6" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "D4A6Q6", "url": "https://www.uniprot.org/uniprotkb/D4A6Q6" } ], "pmid": "" }, { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "D4A6Q6", "url": "https://www.uniprot.org/uniprotkb/D4A6Q6" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "D4A6Q6", "url": "https://www.uniprot.org/uniprotkb/D4A6Q6" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "D4A6Q6", "url": "https://www.uniprot.org/uniprotkb/D4A6Q6" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "D4A6Q6", "url": "https://www.uniprot.org/uniprotkb/D4A6Q6" } ], "pmid": "" }, { "name": "alpha-tubulin binding", "id": "GO:0043014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043014", "evidence": [ { "database": "UniProtKB", "id": "D4A6Q6", "url": "https://www.uniprot.org/uniprotkb/D4A6Q6" } ], "pmid": "" }, { "name": "ATP-dependent activity, acting on DNA", "id": "GO:0008094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008094", "evidence": [ { "database": "UniProtKB", "id": "D4A6Q6", "url": "https://www.uniprot.org/uniprotkb/D4A6Q6" } ], "pmid": "" }, { "name": "ATP-dependent chromatin remodeler activity", "id": "GO:0140658", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140658", "evidence": [ { "database": "UniProtKB", "id": "D4A6Q6", "url": "https://www.uniprot.org/uniprotkb/D4A6Q6" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D4A6Q6", "url": "https://www.uniprot.org/uniprotkb/D4A6Q6" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "D4A6Q6", "url": "https://www.uniprot.org/uniprotkb/D4A6Q6" } ], "pmid": "" }, { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "D4A6Q6", "url": "https://www.uniprot.org/uniprotkb/D4A6Q6" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "D4A6Q6", "url": "https://www.uniprot.org/uniprotkb/D4A6Q6" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "D4A6Q6", "url": "https://www.uniprot.org/uniprotkb/D4A6Q6" } ], "pmid": "" }, { "name": "Ino80 complex", "id": "GO:0031011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031011", "evidence": [ { "database": "UniProtKB", "id": "D4A6Q6", "url": "https://www.uniprot.org/uniprotkb/D4A6Q6" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "D4A6Q6", "url": "https://www.uniprot.org/uniprotkb/D4A6Q6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D4A6Q6-1" }, { "uniprot_canonical_ac": "D4A6R1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4A6R1", "url": "https://www.uniprot.org/uniprotkb/D4A6R1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 345, "chemical_mass": 38710.0, "gene_names": "Fbxo44;Fbxo44;RGD1562463", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D4A6R1", "url": "https://www.uniprot.org/uniprotkb/D4A6R1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "D4A6R1", "url": "https://www.uniprot.org/uniprotkb/D4A6R1" } ], "pmid": "" }, { "name": "SCF ubiquitin ligase complex", "id": "GO:0019005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019005", "evidence": [ { "database": "UniProtKB", "id": "D4A6R1", "url": "https://www.uniprot.org/uniprotkb/D4A6R1" } ], "pmid": "" } ], "biological_process": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "D4A6R1", "url": "https://www.uniprot.org/uniprotkb/D4A6R1" } ], "pmid": "" }, { "name": "proteasomal protein catabolic process", "id": "GO:0010498", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010498", "evidence": [ { "database": "UniProtKB", "id": "D4A6R1", "url": "https://www.uniprot.org/uniprotkb/D4A6R1" } ], "pmid": "" }, { "name": "ERAD pathway", "id": "GO:0036503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036503", "evidence": [ { "database": "UniProtKB", "id": "D4A6R1", "url": "https://www.uniprot.org/uniprotkb/D4A6R1" } ], "pmid": "" }, { "name": "glycoprotein catabolic process", "id": "GO:0006516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006516", "evidence": [ { "database": "UniProtKB", "id": "D4A6R1", "url": "https://www.uniprot.org/uniprotkb/D4A6R1" } ], "pmid": "" }, { "name": "SCF-dependent proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0031146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031146", "evidence": [ { "database": "UniProtKB", "id": "D4A6R1", "url": "https://www.uniprot.org/uniprotkb/D4A6R1" } ], "pmid": "" } ], "molecular_function": [ { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "D4A6R1", "url": "https://www.uniprot.org/uniprotkb/D4A6R1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D4A6R1-1" }, { "uniprot_canonical_ac": "D4A6U4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4A6U4", "url": "https://www.uniprot.org/uniprotkb/D4A6U4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1417, "chemical_mass": 154809.0, "gene_names": "Tecpr2;RGD1307503;Tecpr2", "protein_name": "", "disease": [ { "disease_id": "DOID:0110801", "name": "hereditary sensory and autonomic neuropathy type 9", "description": "A hereditary sensory and autonomic neuropathy characterized by global developmental delay, intellectual disability, hypotonia, dysarthria, abnormal gait, hyporeflexia, and central hypoventilation or apnea that has_material_basis_in homozygous or compound heterozygous mutation in the TECPR2 gene on chromosome 14q32. Additional symptoms due to peripheral neuropathy or autonomic dysfunction are more variable.", "url": "https://disease-ontology.org/term/DOID:0110801", "evidence": [ { "id": "0110801", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110801" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "D4A6U4", "url": "https://www.uniprot.org/uniprotkb/D4A6U4" } ], "pmid": "" } ], "biological_process": [ { "name": "protein exit from endoplasmic reticulum", "id": "GO:0032527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032527", "evidence": [ { "database": "UniProtKB", "id": "D4A6U4", "url": "https://www.uniprot.org/uniprotkb/D4A6U4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "D4A6U4-1", "start_pos": "557", "end_pos": "557", "site_lbl": "Thr557", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 557, "start_aa": "Thr", "end_pos": 557, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr557", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "D4A6U4-1" }, { "uniprot_canonical_ac": "D4A715-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4A715", "url": "https://www.uniprot.org/uniprotkb/D4A715" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 743, "chemical_mass": 84601.0, "gene_names": "Zfp366;LOC100360041;Zfp366;Znf366", "protein_name": "Zinc finger protein 366", "disease": [ { "disease_id": "DOID:11198", "name": "DiGeorge syndrome", "description": "A syndrome that has_material_basis_in a large deletion of the chromosome 22q11.2 region which includes the DGS gene needed for development of the thymus and related glands with subsequent lack of T-cell production.", "url": "https://disease-ontology.org/term/DOID:11198", "evidence": [ { "id": "11198", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11198" } ], "weight": 0.0 } ], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "D4A715", "url": "https://www.uniprot.org/uniprotkb/D4A715" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "D4A715", "url": "https://www.uniprot.org/uniprotkb/D4A715" } ], "pmid": "" }, { "name": "response to estrogen", "id": "GO:0043627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043627", "evidence": [ { "database": "UniProtKB", "id": "D4A715", "url": "https://www.uniprot.org/uniprotkb/D4A715" } ], "pmid": "" }, { "name": "negative regulation of intracellular estrogen receptor signaling pathway", "id": "GO:0033147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033147", "evidence": [ { "database": "UniProtKB", "id": "D4A715", "url": "https://www.uniprot.org/uniprotkb/D4A715" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "D4A715", "url": "https://www.uniprot.org/uniprotkb/D4A715" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "D4A715", "url": "https://www.uniprot.org/uniprotkb/D4A715" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "D4A715", "url": "https://www.uniprot.org/uniprotkb/D4A715" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "D4A715", "url": "https://www.uniprot.org/uniprotkb/D4A715" } ], "pmid": "" }, { "name": "nuclear estrogen receptor binding", "id": "GO:0030331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030331", "evidence": [ { "database": "UniProtKB", "id": "D4A715", "url": "https://www.uniprot.org/uniprotkb/D4A715" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D4A715", "url": "https://www.uniprot.org/uniprotkb/D4A715" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "D4A715", "url": "https://www.uniprot.org/uniprotkb/D4A715" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "D4A715-1", "start_pos": "162", "end_pos": "162", "site_lbl": "Thr162", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 162, "start_aa": "Thr", "end_pos": 162, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr162", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "D4A715-1" }, { "uniprot_canonical_ac": "D4A755-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4A755", "url": "https://www.uniprot.org/uniprotkb/D4A755" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 312, "chemical_mass": 35366.0, "gene_names": "Or4k48b;Olr775;Or4k48b", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "D4A755", "url": "https://www.uniprot.org/uniprotkb/D4A755" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "D4A755", "url": "https://www.uniprot.org/uniprotkb/D4A755" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "D4A755", "url": "https://www.uniprot.org/uniprotkb/D4A755" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D4A755-1" }, { "uniprot_canonical_ac": "D4A7B4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4A7B4", "url": "https://www.uniprot.org/uniprotkb/D4A7B4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 160, "chemical_mass": 18766.0, "gene_names": "AABR07034641.1", "protein_name": "Large ribosomal subunit protein eL21", "disease": [], "biological_process": [ { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "D4A7B4", "url": "https://www.uniprot.org/uniprotkb/D4A7B4" } ], "pmid": "" } ], "molecular_function": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "D4A7B4", "url": "https://www.uniprot.org/uniprotkb/D4A7B4" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosolic large ribosomal subunit", "id": "GO:0022625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022625", "evidence": [ { "database": "UniProtKB", "id": "D4A7B4", "url": "https://www.uniprot.org/uniprotkb/D4A7B4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D4A7B4-1" }, { "uniprot_canonical_ac": "D4A7F0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4A7F0", "url": "https://www.uniprot.org/uniprotkb/D4A7F0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1886, "chemical_mass": 212493.0, "gene_names": "Ubr3;RGD1565257;Ubr3", "protein_name": "E3 ubiquitin-protein ligase", "disease": [], "biological_process": [ { "name": "olfactory behavior", "id": "GO:0042048", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042048", "evidence": [ { "database": "UniProtKB", "id": "D4A7F0", "url": "https://www.uniprot.org/uniprotkb/D4A7F0" } ], "pmid": "" }, { "name": "embryo development ending in birth or egg hatching", "id": "GO:0009792", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009792", "evidence": [ { "database": "UniProtKB", "id": "D4A7F0", "url": "https://www.uniprot.org/uniprotkb/D4A7F0" } ], "pmid": "" }, { "name": "negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel", "id": "GO:1904878", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904878", "evidence": [ { "database": "UniProtKB", "id": "D4A7F0", "url": "https://www.uniprot.org/uniprotkb/D4A7F0" } ], "pmid": "" }, { "name": "in utero embryonic development", "id": "GO:0001701", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001701", "evidence": [ { "database": "UniProtKB", "id": "D4A7F0", "url": "https://www.uniprot.org/uniprotkb/D4A7F0" } ], "pmid": "" }, { "name": "suckling behavior", "id": "GO:0001967", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001967", "evidence": [ { "database": "UniProtKB", "id": "D4A7F0", "url": "https://www.uniprot.org/uniprotkb/D4A7F0" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "D4A7F0", "url": "https://www.uniprot.org/uniprotkb/D4A7F0" } ], "pmid": "" }, { "name": "positive regulation of protein catabolic process", "id": "GO:0045732", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045732", "evidence": [ { "database": "UniProtKB", "id": "D4A7F0", "url": "https://www.uniprot.org/uniprotkb/D4A7F0" } ], "pmid": "" }, { "name": "sensory perception of smell", "id": "GO:0007608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007608", "evidence": [ { "database": "UniProtKB", "id": "D4A7F0", "url": "https://www.uniprot.org/uniprotkb/D4A7F0" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "D4A7F0", "url": "https://www.uniprot.org/uniprotkb/D4A7F0" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process via the N-end rule pathway", "id": "GO:0071596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071596", "evidence": [ { "database": "UniProtKB", "id": "D4A7F0", "url": "https://www.uniprot.org/uniprotkb/D4A7F0" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "D4A7F0", "url": "https://www.uniprot.org/uniprotkb/D4A7F0" } ], "pmid": "" }, { "name": "ubiquitin ligase complex", "id": "GO:0000151", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000151", "evidence": [ { "database": "UniProtKB", "id": "D4A7F0", "url": "https://www.uniprot.org/uniprotkb/D4A7F0" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "D4A7F0", "url": "https://www.uniprot.org/uniprotkb/D4A7F0" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "D4A7F0", "url": "https://www.uniprot.org/uniprotkb/D4A7F0" } ], "pmid": "" }, { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "D4A7F0", "url": "https://www.uniprot.org/uniprotkb/D4A7F0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D4A7F0-1" }, { "uniprot_canonical_ac": "D4A7S7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4A7S7", "url": "https://www.uniprot.org/uniprotkb/D4A7S7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 647, "chemical_mass": 71203.0, "gene_names": "Nfe2l3;Nfe2l3", "protein_name": "Nuclear factor erythroid 2-related factor 3", "disease": [], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "D4A7S7", "url": "https://www.uniprot.org/uniprotkb/D4A7S7" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "D4A7S7", "url": "https://www.uniprot.org/uniprotkb/D4A7S7" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "D4A7S7", "url": "https://www.uniprot.org/uniprotkb/D4A7S7" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D4A7S7", "url": "https://www.uniprot.org/uniprotkb/D4A7S7" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulator complex", "id": "GO:0090575", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090575", "evidence": [ { "database": "UniProtKB", "id": "D4A7S7", "url": "https://www.uniprot.org/uniprotkb/D4A7S7" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "D4A7S7", "url": "https://www.uniprot.org/uniprotkb/D4A7S7" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "D4A7S7", "url": "https://www.uniprot.org/uniprotkb/D4A7S7" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "D4A7S7", "url": "https://www.uniprot.org/uniprotkb/D4A7S7" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "D4A7S7", "url": "https://www.uniprot.org/uniprotkb/D4A7S7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D4A7S7-1" }, { "uniprot_canonical_ac": "D4A7Z1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4A7Z1", "url": "https://www.uniprot.org/uniprotkb/D4A7Z1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1612, "chemical_mass": 178256.0, "gene_names": "Rimbp3;RGD1563657;Rimbp3", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D4A7Z1", "url": "https://www.uniprot.org/uniprotkb/D4A7Z1" } ], "pmid": "" }, { "name": "manchette", "id": "GO:0002177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002177", "evidence": [ { "database": "UniProtKB", "id": "D4A7Z1", "url": "https://www.uniprot.org/uniprotkb/D4A7Z1" } ], "pmid": "" } ], "biological_process": [ { "name": "fertilization", "id": "GO:0009566", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009566", "evidence": [ { "database": "UniProtKB", "id": "D4A7Z1", "url": "https://www.uniprot.org/uniprotkb/D4A7Z1" } ], "pmid": "" }, { "name": "spermatid development", "id": "GO:0007286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007286", "evidence": [ { "database": "UniProtKB", "id": "D4A7Z1", "url": "https://www.uniprot.org/uniprotkb/D4A7Z1" } ], "pmid": "" } ], "molecular_function": [ { "name": "benzodiazepine receptor binding", "id": "GO:0030156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030156", "evidence": [ { "database": "UniProtKB", "id": "D4A7Z1", "url": "https://www.uniprot.org/uniprotkb/D4A7Z1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "D4A7Z1-1", "start_pos": "906", "end_pos": "906", "site_lbl": "Thr906", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 906, "start_aa": "Thr", "end_pos": 906, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr906", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "D4A7Z1-1" }, { "uniprot_canonical_ac": "D4A846-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4A846", "url": "https://www.uniprot.org/uniprotkb/D4A846" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 318, "chemical_mass": 35595.0, "gene_names": "Or10ag58;Olr562;Or10ag58", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "D4A846", "url": "https://www.uniprot.org/uniprotkb/D4A846" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "D4A846", "url": "https://www.uniprot.org/uniprotkb/D4A846" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "D4A846", "url": "https://www.uniprot.org/uniprotkb/D4A846" } ], "pmid": "" } ], "biological_process": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "D4A846", "url": "https://www.uniprot.org/uniprotkb/D4A846" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D4A846-1" }, { "uniprot_canonical_ac": "D4A869-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4A869", "url": "https://www.uniprot.org/uniprotkb/D4A869" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 175, "chemical_mass": 20500.0, "gene_names": "LOC120100607;LOC102551064;LOC120100607", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D4A869-1" }, { "uniprot_canonical_ac": "D4A8C8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4A8C8", "url": "https://www.uniprot.org/uniprotkb/D4A8C8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 929, "chemical_mass": 105757.0, "gene_names": "Paxbp1;Gcfc1", "protein_name": "", "disease": [], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "D4A8C8", "url": "https://www.uniprot.org/uniprotkb/D4A8C8" } ], "pmid": "" }, { "name": "histone methyltransferase binding", "id": "GO:1990226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990226", "evidence": [ { "database": "UniProtKB", "id": "D4A8C8", "url": "https://www.uniprot.org/uniprotkb/D4A8C8" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D4A8C8", "url": "https://www.uniprot.org/uniprotkb/D4A8C8" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "D4A8C8", "url": "https://www.uniprot.org/uniprotkb/D4A8C8" } ], "pmid": "" }, { "name": "regulation of skeletal muscle satellite cell proliferation", "id": "GO:0014842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014842", "evidence": [ { "database": "UniProtKB", "id": "D4A8C8", "url": "https://www.uniprot.org/uniprotkb/D4A8C8" } ], "pmid": "" }, { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "D4A8C8", "url": "https://www.uniprot.org/uniprotkb/D4A8C8" } ], "pmid": "" }, { "name": "positive regulation of myoblast proliferation", "id": "GO:2000288", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000288", "evidence": [ { "database": "UniProtKB", "id": "D4A8C8", "url": "https://www.uniprot.org/uniprotkb/D4A8C8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D4A8C8-1" }, { "uniprot_canonical_ac": "D4A8F8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4A8F8", "url": "https://www.uniprot.org/uniprotkb/D4A8F8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 307, "chemical_mass": 34309.0, "gene_names": "Or2d3c;Olr221;Or2d3c", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "D4A8F8", "url": "https://www.uniprot.org/uniprotkb/D4A8F8" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "D4A8F8", "url": "https://www.uniprot.org/uniprotkb/D4A8F8" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "D4A8F8", "url": "https://www.uniprot.org/uniprotkb/D4A8F8" } ], "pmid": "" } ], "biological_process": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "D4A8F8", "url": "https://www.uniprot.org/uniprotkb/D4A8F8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "D4A8F8-1", "start_pos": "282", "end_pos": "282", "site_lbl": "Thr282", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 282, "start_aa": "Thr", "end_pos": 282, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr282", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "D4A8F8-1" }, { "uniprot_canonical_ac": "D4A8H5-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4A8H5", "url": "https://www.uniprot.org/uniprotkb/D4A8H5" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 413, "chemical_mass": 45944.0, "gene_names": "Ppp4r2;Ppp4r2", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D4A8H5", "url": "https://www.uniprot.org/uniprotkb/D4A8H5" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "D4A8H5", "url": "https://www.uniprot.org/uniprotkb/D4A8H5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "D4A8H5", "url": "https://www.uniprot.org/uniprotkb/D4A8H5" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "D4A8H5", "url": "https://www.uniprot.org/uniprotkb/D4A8H5" } ], "pmid": "" }, { "name": "protein phosphatase 4 complex", "id": "GO:0030289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030289", "evidence": [ { "database": "UniProtKB", "id": "D4A8H5", "url": "https://www.uniprot.org/uniprotkb/D4A8H5" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "D4A8H5", "url": "https://www.uniprot.org/uniprotkb/D4A8H5" } ], "pmid": "" }, { "name": "protein phosphatase regulator activity", "id": "GO:0019888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019888", "evidence": [ { "database": "UniProtKB", "id": "D4A8H5", "url": "https://www.uniprot.org/uniprotkb/D4A8H5" } ], "pmid": "" } ], "biological_process": [ { "name": "hematopoietic progenitor cell differentiation", "id": "GO:0002244", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002244", "evidence": [ { "database": "UniProtKB", "id": "D4A8H5", "url": "https://www.uniprot.org/uniprotkb/D4A8H5" } ], "pmid": "" }, { "name": "regulation of double-strand break repair via homologous recombination", "id": "GO:0010569", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010569", "evidence": [ { "database": "UniProtKB", "id": "D4A8H5", "url": "https://www.uniprot.org/uniprotkb/D4A8H5" } ], "pmid": "" }, { "name": "regulation of double-strand break repair", "id": "GO:2000779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000779", "evidence": [ { "database": "UniProtKB", "id": "D4A8H5", "url": "https://www.uniprot.org/uniprotkb/D4A8H5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D4A8H5-1" }, { "uniprot_canonical_ac": "D4A8J5-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4A8J5", "url": "https://www.uniprot.org/uniprotkb/D4A8J5" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 780, "chemical_mass": 89843.0, "gene_names": "Zfp790;Zfp790", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D4A8J5", "url": "https://www.uniprot.org/uniprotkb/D4A8J5" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "D4A8J5", "url": "https://www.uniprot.org/uniprotkb/D4A8J5" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "D4A8J5", "url": "https://www.uniprot.org/uniprotkb/D4A8J5" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "D4A8J5", "url": "https://www.uniprot.org/uniprotkb/D4A8J5" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "D4A8J5", "url": "https://www.uniprot.org/uniprotkb/D4A8J5" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "D4A8J5", "url": "https://www.uniprot.org/uniprotkb/D4A8J5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D4A8J5-1" }, { "uniprot_canonical_ac": "D4A932-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4A932", "url": "https://www.uniprot.org/uniprotkb/D4A932" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1031, "chemical_mass": 114192.0, "gene_names": "Plekhm2;Plekhm2", "protein_name": "Pleckstrin homology domain-containing family M member 2", "disease": [], "cellular_component": [ { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "D4A932", "url": "https://www.uniprot.org/uniprotkb/D4A932" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "D4A932", "url": "https://www.uniprot.org/uniprotkb/D4A932" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of protein localization", "id": "GO:0032880", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032880", "evidence": [ { "database": "UniProtKB", "id": "D4A932", "url": "https://www.uniprot.org/uniprotkb/D4A932" } ], "pmid": "" }, { "name": "Golgi organization", "id": "GO:0007030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007030", "evidence": [ { "database": "UniProtKB", "id": "D4A932", "url": "https://www.uniprot.org/uniprotkb/D4A932" } ], "pmid": "" }, { "name": "lysosome localization", "id": "GO:0032418", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032418", "evidence": [ { "database": "UniProtKB", "id": "D4A932", "url": "https://www.uniprot.org/uniprotkb/D4A932" } ], "pmid": "" }, { "name": "natural killer cell mediated cytotoxicity", "id": "GO:0042267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042267", "evidence": [ { "database": "UniProtKB", "id": "D4A932", "url": "https://www.uniprot.org/uniprotkb/D4A932" } ], "pmid": "" } ], "molecular_function": [ { "name": "kinesin binding", "id": "GO:0019894", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019894", "evidence": [ { "database": "UniProtKB", "id": "D4A932", "url": "https://www.uniprot.org/uniprotkb/D4A932" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D4A932-1" }, { "uniprot_canonical_ac": "D4A986-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4A986", "url": "https://www.uniprot.org/uniprotkb/D4A986" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 412, "chemical_mass": 43510.0, "gene_names": "Mbd2", "protein_name": "", "disease": [ { "disease_id": "DOID:224", "name": "transient cerebral ischemia", "description": "A brain ischemia that is characterized by ischemia of brief duration and without resultant tissue death.", "url": "https://disease-ontology.org/term/DOID:224", "evidence": [ { "id": "224", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:224" } ], "weight": 0.0 }, { "disease_id": "DOID:5419", "name": "schizophrenia", "description": "A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness.", "url": "https://disease-ontology.org/term/DOID:5419", "evidence": [ { "id": "5419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5419" } ], "weight": 0.0 }, { "disease_id": "DOID:7148", "name": "rheumatoid arthritis", "description": "An arthritis that is an autoimmune disease which attacks healthy cells and tissue located_in joint.", "url": "https://disease-ontology.org/term/DOID:7148", "evidence": [ { "id": "7148", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7148" } ], "weight": 0.0 }, { "disease_id": "DOID:8456", "name": "choline deficiency disease", "description": "A nutritional deficiency disease that is characterized by deficiency of choline, which has been associated with development of fatty liver, and possibly has_material_basis_in inadequate intake and exacerbated by a genetic predisposition.", "url": "https://disease-ontology.org/term/DOID:8456", "evidence": [ { "id": "8456", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8456" } ], "weight": 0.0 }, { "disease_id": "DOID:9744", "name": "type 1 diabetes mellitus", "description": "A diabetes mellitus that is characterized by destruction of pancreatic beta cells resulting in absent or extremely low insulin production.", "url": "https://disease-ontology.org/term/DOID:9744", "evidence": [ { "id": "9744", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9744" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "D4A986", "url": "https://www.uniprot.org/uniprotkb/D4A986" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "D4A986", "url": "https://www.uniprot.org/uniprotkb/D4A986" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "D4A986", "url": "https://www.uniprot.org/uniprotkb/D4A986" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "D4A986", "url": "https://www.uniprot.org/uniprotkb/D4A986" } ], "pmid": "" }, { "name": "protein domain specific binding", "id": "GO:0019904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019904", "evidence": [ { "database": "UniProtKB", "id": "D4A986", "url": "https://www.uniprot.org/uniprotkb/D4A986" } ], "pmid": "" }, { "name": "methyl-CpG binding", "id": "GO:0008327", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008327", "evidence": [ { "database": "UniProtKB", "id": "D4A986", "url": "https://www.uniprot.org/uniprotkb/D4A986" } ], "pmid": "" }, { "name": "siRNA binding", "id": "GO:0035197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035197", "evidence": [ { "database": "UniProtKB", "id": "D4A986", "url": "https://www.uniprot.org/uniprotkb/D4A986" } ], "pmid": "" }, { "name": "C2H2 zinc finger domain binding", "id": "GO:0070742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070742", "evidence": [ { "database": "UniProtKB", "id": "D4A986", "url": "https://www.uniprot.org/uniprotkb/D4A986" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "D4A986", "url": "https://www.uniprot.org/uniprotkb/D4A986" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "D4A986", "url": "https://www.uniprot.org/uniprotkb/D4A986" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "D4A986", "url": "https://www.uniprot.org/uniprotkb/D4A986" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "D4A986", "url": "https://www.uniprot.org/uniprotkb/D4A986" } ], "pmid": "" }, { "name": "regulation of cell population proliferation", "id": "GO:0042127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042127", "evidence": [ { "database": "UniProtKB", "id": "D4A986", "url": "https://www.uniprot.org/uniprotkb/D4A986" } ], "pmid": "" }, { "name": "response to nutrient levels", "id": "GO:0031667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031667", "evidence": [ { "database": "UniProtKB", "id": "D4A986", "url": "https://www.uniprot.org/uniprotkb/D4A986" } ], "pmid": "" }, { "name": "response to mechanical stimulus", "id": "GO:0009612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009612", "evidence": [ { "database": "UniProtKB", "id": "D4A986", "url": "https://www.uniprot.org/uniprotkb/D4A986" } ], "pmid": "" }, { "name": "response to estradiol", "id": "GO:0032355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032355", "evidence": [ { "database": "UniProtKB", "id": "D4A986", "url": "https://www.uniprot.org/uniprotkb/D4A986" } ], "pmid": "" }, { "name": "epigenetic regulation of gene expression", "id": "GO:0040029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040029", "evidence": [ { "database": "UniProtKB", "id": "D4A986", "url": "https://www.uniprot.org/uniprotkb/D4A986" } ], "pmid": "" }, { "name": "embryonic organ development", "id": "GO:0048568", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048568", "evidence": [ { "database": "UniProtKB", "id": "D4A986", "url": "https://www.uniprot.org/uniprotkb/D4A986" } ], "pmid": "" }, { "name": "DNA methylation-dependent constitutive heterochromatin formation", "id": "GO:0006346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006346", "evidence": [ { "database": "UniProtKB", "id": "D4A986", "url": "https://www.uniprot.org/uniprotkb/D4A986" } ], "pmid": "" }, { "name": "positive regulation of Wnt signaling pathway", "id": "GO:0030177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030177", "evidence": [ { "database": "UniProtKB", "id": "D4A986", "url": "https://www.uniprot.org/uniprotkb/D4A986" } ], "pmid": "" }, { "name": "maternal behavior", "id": "GO:0042711", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042711", "evidence": [ { "database": "UniProtKB", "id": "D4A986", "url": "https://www.uniprot.org/uniprotkb/D4A986" } ], "pmid": "" }, { "name": "protein-containing complex assembly", "id": "GO:0065003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0065003", "evidence": [ { "database": "UniProtKB", "id": "D4A986", "url": "https://www.uniprot.org/uniprotkb/D4A986" } ], "pmid": "" }, { "name": "ventricular cardiac muscle tissue development", "id": "GO:0003229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003229", "evidence": [ { "database": "UniProtKB", "id": "D4A986", "url": "https://www.uniprot.org/uniprotkb/D4A986" } ], "pmid": "" }, { "name": "cellular response to serotonin", "id": "GO:1904015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904015", "evidence": [ { "database": "UniProtKB", "id": "D4A986", "url": "https://www.uniprot.org/uniprotkb/D4A986" } ], "pmid": "" }, { "name": "response to bisphenol A", "id": "GO:1903925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903925", "evidence": [ { "database": "UniProtKB", "id": "D4A986", "url": "https://www.uniprot.org/uniprotkb/D4A986" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D4A986", "url": "https://www.uniprot.org/uniprotkb/D4A986" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "D4A986", "url": "https://www.uniprot.org/uniprotkb/D4A986" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "D4A986", "url": "https://www.uniprot.org/uniprotkb/D4A986" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "D4A986", "url": "https://www.uniprot.org/uniprotkb/D4A986" } ], "pmid": "" }, { "name": "histone deacetylase complex", "id": "GO:0000118", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000118", "evidence": [ { "database": "UniProtKB", "id": "D4A986", "url": "https://www.uniprot.org/uniprotkb/D4A986" } ], "pmid": "" }, { "name": "heterochromatin", "id": "GO:0000792", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000792", "evidence": [ { "database": "UniProtKB", "id": "D4A986", "url": "https://www.uniprot.org/uniprotkb/D4A986" } ], "pmid": "" }, { "name": "NuRD complex", "id": "GO:0016581", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016581", "evidence": [ { "database": "UniProtKB", "id": "D4A986", "url": "https://www.uniprot.org/uniprotkb/D4A986" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D4A986-1" }, { "uniprot_canonical_ac": "D4A9B0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4A9B0", "url": "https://www.uniprot.org/uniprotkb/D4A9B0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 983, "chemical_mass": 110459.0, "gene_names": "Srbd1;RGD1562788;Srbd1", "protein_name": "S1 RNA-binding domain-containing protein 1", "disease": [], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "D4A9B0", "url": "https://www.uniprot.org/uniprotkb/D4A9B0" } ], "pmid": "" }, { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "D4A9B0", "url": "https://www.uniprot.org/uniprotkb/D4A9B0" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "D4A9B0", "url": "https://www.uniprot.org/uniprotkb/D4A9B0" } ], "pmid": "" } ], "biological_process": [ { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "D4A9B0", "url": "https://www.uniprot.org/uniprotkb/D4A9B0" } ], "pmid": "" }, { "name": "nucleobase-containing compound metabolic process", "id": "GO:0006139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006139", "evidence": [ { "database": "UniProtKB", "id": "D4A9B0", "url": "https://www.uniprot.org/uniprotkb/D4A9B0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D4A9B0-1" }, { "uniprot_canonical_ac": "D4A9N5-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4A9N5", "url": "https://www.uniprot.org/uniprotkb/D4A9N5" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 643, "chemical_mass": 71920.0, "gene_names": "Trim25", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "disease": [], "biological_process": [ { "name": "regulation of viral entry into host cell", "id": "GO:0046596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046596", "evidence": [ { "database": "UniProtKB", "id": "D4A9N5", "url": "https://www.uniprot.org/uniprotkb/D4A9N5" } ], "pmid": "" }, { "name": "suppression of viral release by host", "id": "GO:0044790", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044790", "evidence": [ { "database": "UniProtKB", "id": "D4A9N5", "url": "https://www.uniprot.org/uniprotkb/D4A9N5" } ], "pmid": "" }, { "name": "response to oxidative stress", "id": "GO:0006979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006979", "evidence": [ { "database": "UniProtKB", "id": "D4A9N5", "url": "https://www.uniprot.org/uniprotkb/D4A9N5" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "D4A9N5", "url": "https://www.uniprot.org/uniprotkb/D4A9N5" } ], "pmid": "" }, { "name": "cellular response to leukemia inhibitory factor", "id": "GO:1990830", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990830", "evidence": [ { "database": "UniProtKB", "id": "D4A9N5", "url": "https://www.uniprot.org/uniprotkb/D4A9N5" } ], "pmid": "" }, { "name": "regulation of protein localization", "id": "GO:0032880", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032880", "evidence": [ { "database": "UniProtKB", "id": "D4A9N5", "url": "https://www.uniprot.org/uniprotkb/D4A9N5" } ], "pmid": "" }, { "name": "positive regulation of canonical NF-kappaB signal transduction", "id": "GO:0043123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043123", "evidence": [ { "database": "UniProtKB", "id": "D4A9N5", "url": "https://www.uniprot.org/uniprotkb/D4A9N5" } ], "pmid": "" }, { "name": "response to estrogen", "id": "GO:0043627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043627", "evidence": [ { "database": "UniProtKB", "id": "D4A9N5", "url": "https://www.uniprot.org/uniprotkb/D4A9N5" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "D4A9N5", "url": "https://www.uniprot.org/uniprotkb/D4A9N5" } ], "pmid": "" }, { "name": "ERAD pathway", "id": "GO:0036503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036503", "evidence": [ { "database": "UniProtKB", "id": "D4A9N5", "url": "https://www.uniprot.org/uniprotkb/D4A9N5" } ], "pmid": "" }, { "name": "protein K48-linked ubiquitination", "id": "GO:0070936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070936", "evidence": [ { "database": "UniProtKB", "id": "D4A9N5", "url": "https://www.uniprot.org/uniprotkb/D4A9N5" } ], "pmid": "" }, { "name": "response to vitamin D", "id": "GO:0033280", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033280", "evidence": [ { "database": "UniProtKB", "id": "D4A9N5", "url": "https://www.uniprot.org/uniprotkb/D4A9N5" } ], "pmid": "" }, { "name": "protein monoubiquitination", "id": "GO:0006513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006513", "evidence": [ { "database": "UniProtKB", "id": "D4A9N5", "url": "https://www.uniprot.org/uniprotkb/D4A9N5" } ], "pmid": "" }, { "name": "host-mediated suppression of symbiont invasion", "id": "GO:0046597", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046597", "evidence": [ { "database": "UniProtKB", "id": "D4A9N5", "url": "https://www.uniprot.org/uniprotkb/D4A9N5" } ], "pmid": "" }, { "name": "viral release from host cell", "id": "GO:0019076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019076", "evidence": [ { "database": "UniProtKB", "id": "D4A9N5", "url": "https://www.uniprot.org/uniprotkb/D4A9N5" } ], "pmid": "" }, { "name": "cytoplasmic pattern recognition receptor signaling pathway", "id": "GO:0002753", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002753", "evidence": [ { "database": "UniProtKB", "id": "D4A9N5", "url": "https://www.uniprot.org/uniprotkb/D4A9N5" } ], "pmid": "" }, { "name": "antiviral innate immune response", "id": "GO:0140374", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140374", "evidence": [ { "database": "UniProtKB", "id": "D4A9N5", "url": "https://www.uniprot.org/uniprotkb/D4A9N5" } ], "pmid": "" } ], "molecular_function": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "D4A9N5", "url": "https://www.uniprot.org/uniprotkb/D4A9N5" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "D4A9N5", "url": "https://www.uniprot.org/uniprotkb/D4A9N5" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "D4A9N5", "url": "https://www.uniprot.org/uniprotkb/D4A9N5" } ], "pmid": "" }, { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "D4A9N5", "url": "https://www.uniprot.org/uniprotkb/D4A9N5" } ], "pmid": "" }, { "name": "ligase activity", "id": "GO:0016874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016874", "evidence": [ { "database": "UniProtKB", "id": "D4A9N5", "url": "https://www.uniprot.org/uniprotkb/D4A9N5" } ], "pmid": "" }, { "name": "RIG-I binding", "id": "GO:0039552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0039552", "evidence": [ { "database": "UniProtKB", "id": "D4A9N5", "url": "https://www.uniprot.org/uniprotkb/D4A9N5" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D4A9N5", "url": "https://www.uniprot.org/uniprotkb/D4A9N5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "D4A9N5", "url": "https://www.uniprot.org/uniprotkb/D4A9N5" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "D4A9N5", "url": "https://www.uniprot.org/uniprotkb/D4A9N5" } ], "pmid": "" }, { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "D4A9N5", "url": "https://www.uniprot.org/uniprotkb/D4A9N5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D4A9N5-1" }, { "uniprot_canonical_ac": "D4A9W0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4A9W0", "url": "https://www.uniprot.org/uniprotkb/D4A9W0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 356, "chemical_mass": 40141.0, "gene_names": "Aim2;Aim2", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D4A9W0", "url": "https://www.uniprot.org/uniprotkb/D4A9W0" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "D4A9W0", "url": "https://www.uniprot.org/uniprotkb/D4A9W0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "D4A9W0", "url": "https://www.uniprot.org/uniprotkb/D4A9W0" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "D4A9W0", "url": "https://www.uniprot.org/uniprotkb/D4A9W0" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "D4A9W0", "url": "https://www.uniprot.org/uniprotkb/D4A9W0" } ], "pmid": "" }, { "name": "site of double-strand break", "id": "GO:0035861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035861", "evidence": [ { "database": "UniProtKB", "id": "D4A9W0", "url": "https://www.uniprot.org/uniprotkb/D4A9W0" } ], "pmid": "" }, { "name": "AIM2 inflammasome complex", "id": "GO:0097169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097169", "evidence": [ { "database": "UniProtKB", "id": "D4A9W0", "url": "https://www.uniprot.org/uniprotkb/D4A9W0" } ], "pmid": "" } ], "molecular_function": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "D4A9W0", "url": "https://www.uniprot.org/uniprotkb/D4A9W0" } ], "pmid": "" }, { "name": "double-stranded DNA binding", "id": "GO:0003690", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003690", "evidence": [ { "database": "UniProtKB", "id": "D4A9W0", "url": "https://www.uniprot.org/uniprotkb/D4A9W0" } ], "pmid": "" }, { "name": "signaling adaptor activity", "id": "GO:0035591", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035591", "evidence": [ { "database": "UniProtKB", "id": "D4A9W0", "url": "https://www.uniprot.org/uniprotkb/D4A9W0" } ], "pmid": "" }, { "name": "pattern recognition receptor activity", "id": "GO:0038187", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038187", "evidence": [ { "database": "UniProtKB", "id": "D4A9W0", "url": "https://www.uniprot.org/uniprotkb/D4A9W0" } ], "pmid": "" }, { "name": "cysteine-type endopeptidase activator activity", "id": "GO:0140608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140608", "evidence": [ { "database": "UniProtKB", "id": "D4A9W0", "url": "https://www.uniprot.org/uniprotkb/D4A9W0" } ], "pmid": "" } ], "biological_process": [ { "name": "neuron cellular homeostasis", "id": "GO:0070050", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070050", "evidence": [ { "database": "UniProtKB", "id": "D4A9W0", "url": "https://www.uniprot.org/uniprotkb/D4A9W0" } ], "pmid": "" }, { "name": "cellular response to xenobiotic stimulus", "id": "GO:0071466", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071466", "evidence": [ { "database": "UniProtKB", "id": "D4A9W0", "url": "https://www.uniprot.org/uniprotkb/D4A9W0" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "D4A9W0", "url": "https://www.uniprot.org/uniprotkb/D4A9W0" } ], "pmid": "" }, { "name": "brain development", "id": "GO:0007420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420", "evidence": [ { "database": "UniProtKB", "id": "D4A9W0", "url": "https://www.uniprot.org/uniprotkb/D4A9W0" } ], "pmid": "" }, { "name": "regulation of behavior", "id": "GO:0050795", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050795", "evidence": [ { "database": "UniProtKB", "id": "D4A9W0", "url": "https://www.uniprot.org/uniprotkb/D4A9W0" } ], "pmid": "" }, { "name": "positive regulation of defense response to virus by host", "id": "GO:0002230", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002230", "evidence": [ { "database": "UniProtKB", "id": "D4A9W0", "url": "https://www.uniprot.org/uniprotkb/D4A9W0" } ], "pmid": "" }, { "name": "T cell homeostasis", "id": "GO:0043029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043029", "evidence": [ { "database": "UniProtKB", "id": "D4A9W0", "url": "https://www.uniprot.org/uniprotkb/D4A9W0" } ], "pmid": "" }, { "name": "tumor necrosis factor-mediated signaling pathway", "id": "GO:0033209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033209", "evidence": [ { "database": "UniProtKB", "id": "D4A9W0", "url": "https://www.uniprot.org/uniprotkb/D4A9W0" } ], "pmid": "" }, { "name": "activation of innate immune response", "id": "GO:0002218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002218", "evidence": [ { "database": "UniProtKB", "id": "D4A9W0", "url": "https://www.uniprot.org/uniprotkb/D4A9W0" } ], "pmid": "" }, { "name": "positive regulation of interleukin-1 beta production", "id": "GO:0032731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032731", "evidence": [ { "database": "UniProtKB", "id": "D4A9W0", "url": "https://www.uniprot.org/uniprotkb/D4A9W0" } ], "pmid": "" }, { "name": "cellular response to interferon-beta", "id": "GO:0035458", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035458", "evidence": [ { "database": "UniProtKB", "id": "D4A9W0", "url": "https://www.uniprot.org/uniprotkb/D4A9W0" } ], "pmid": "" }, { "name": "negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction", "id": "GO:0051898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051898", "evidence": [ { "database": "UniProtKB", "id": "D4A9W0", "url": "https://www.uniprot.org/uniprotkb/D4A9W0" } ], "pmid": "" }, { "name": "pyroptotic inflammatory response", "id": "GO:0070269", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070269", "evidence": [ { "database": "UniProtKB", "id": "D4A9W0", "url": "https://www.uniprot.org/uniprotkb/D4A9W0" } ], "pmid": "" }, { "name": "pyroptosome complex assembly", "id": "GO:1904270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904270", "evidence": [ { "database": "UniProtKB", "id": "D4A9W0", "url": "https://www.uniprot.org/uniprotkb/D4A9W0" } ], "pmid": "" }, { "name": "AIM2 inflammasome complex assembly", "id": "GO:0140970", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140970", "evidence": [ { "database": "UniProtKB", "id": "D4A9W0", "url": "https://www.uniprot.org/uniprotkb/D4A9W0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D4A9W0-1" }, { "uniprot_canonical_ac": "D4AA54-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4AA54", "url": "https://www.uniprot.org/uniprotkb/D4AA54" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1355, "chemical_mass": 150489.0, "gene_names": "Plekhh1;Plekhh1", "protein_name": "", "disease": [], "cellular_component": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "D4AA54", "url": "https://www.uniprot.org/uniprotkb/D4AA54" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "D4AA54-1", "start_pos": "1151", "end_pos": "1151", "site_lbl": "Thr1151", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1151, "start_aa": "Thr", "end_pos": 1151, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1151", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "D4AA54-1", "start_pos": "409", "end_pos": "409", "site_lbl": "Thr409", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 409, "start_aa": "Thr", "end_pos": 409, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr409", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "D4AA54-1" }, { "uniprot_canonical_ac": "D4AAC2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4AAC2", "url": "https://www.uniprot.org/uniprotkb/D4AAC2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 310, "chemical_mass": 35149.0, "gene_names": "Or5w13;Olr583;Or5w13", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "D4AAC2", "url": "https://www.uniprot.org/uniprotkb/D4AAC2" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "D4AAC2", "url": "https://www.uniprot.org/uniprotkb/D4AAC2" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "D4AAC2", "url": "https://www.uniprot.org/uniprotkb/D4AAC2" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "D4AAC2", "url": "https://www.uniprot.org/uniprotkb/D4AAC2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D4AAC2-1" }, { "uniprot_canonical_ac": "D4AB06-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4AB06", "url": "https://www.uniprot.org/uniprotkb/D4AB06" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 637, "chemical_mass": 71923.0, "gene_names": "Haus5;Haus5", "protein_name": "", "disease": [], "cellular_component": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "D4AB06", "url": "https://www.uniprot.org/uniprotkb/D4AB06" } ], "pmid": "" }, { "name": "HAUS complex", "id": "GO:0070652", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070652", "evidence": [ { "database": "UniProtKB", "id": "D4AB06", "url": "https://www.uniprot.org/uniprotkb/D4AB06" } ], "pmid": "" }, { "name": "mitotic spindle microtubule", "id": "GO:1990498", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990498", "evidence": [ { "database": "UniProtKB", "id": "D4AB06", "url": "https://www.uniprot.org/uniprotkb/D4AB06" } ], "pmid": "" } ], "biological_process": [ { "name": "centrosome cycle", "id": "GO:0007098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007098", "evidence": [ { "database": "UniProtKB", "id": "D4AB06", "url": "https://www.uniprot.org/uniprotkb/D4AB06" } ], "pmid": "" }, { "name": "spindle assembly", "id": "GO:0051225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051225", "evidence": [ { "database": "UniProtKB", "id": "D4AB06", "url": "https://www.uniprot.org/uniprotkb/D4AB06" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D4AB06-1" }, { "uniprot_canonical_ac": "D4AB62-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4AB62", "url": "https://www.uniprot.org/uniprotkb/D4AB62" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 686, "chemical_mass": 74919.0, "gene_names": "Mslnl;Mslnl", "protein_name": "", "disease": [], "cellular_component": [ { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "D4AB62", "url": "https://www.uniprot.org/uniprotkb/D4AB62" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "D4AB62", "url": "https://www.uniprot.org/uniprotkb/D4AB62" } ], "pmid": "" } ], "biological_process": [ { "name": "cell-matrix adhesion", "id": "GO:0007160", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007160", "evidence": [ { "database": "UniProtKB", "id": "D4AB62", "url": "https://www.uniprot.org/uniprotkb/D4AB62" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D4AB62-1" }, { "uniprot_canonical_ac": "D4AB99-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4AB99", "url": "https://www.uniprot.org/uniprotkb/D4AB99" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 2152, "chemical_mass": 238134.0, "gene_names": "Pcnx2;Pcnxl2", "protein_name": "Pecanex-like protein", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "D4AB99", "url": "https://www.uniprot.org/uniprotkb/D4AB99" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "D4AB99-1", "start_pos": "207", "end_pos": "207", "site_lbl": "Thr207", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 207, "start_aa": "Thr", "end_pos": 207, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr207", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "D4AB99-1", "start_pos": "477", "end_pos": "477", "site_lbl": "Thr477", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 477, "start_aa": "Thr", "end_pos": 477, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr477", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "D4AB99-1" }, { "uniprot_canonical_ac": "D4ABE4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4ABE4", "url": "https://www.uniprot.org/uniprotkb/D4ABE4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 313, "chemical_mass": 35561.0, "gene_names": "Or51v14;Olr113;Or51v14", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "D4ABE4", "url": "https://www.uniprot.org/uniprotkb/D4ABE4" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "D4ABE4", "url": "https://www.uniprot.org/uniprotkb/D4ABE4" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "D4ABE4", "url": "https://www.uniprot.org/uniprotkb/D4ABE4" } ], "pmid": "" } ], "biological_process": [ { "name": "cellular response to lipid", "id": "GO:0071396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071396", "evidence": [ { "database": "UniProtKB", "id": "D4ABE4", "url": "https://www.uniprot.org/uniprotkb/D4ABE4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D4ABE4-1" }, { "uniprot_canonical_ac": "D4ABP2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4ABP2", "url": "https://www.uniprot.org/uniprotkb/D4ABP2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1994, "chemical_mass": 223927.0, "gene_names": "Fer1l4;Fer1l4;LOC100911434", "protein_name": "", "disease": [ { "disease_id": "DOID:11724", "name": "limb-girdle muscular dystrophy", "description": "A muscular dystrophy that is characterized by weakening of the muscles of the hip and shoulders which comprise the limb girdle muscles.", "url": "https://disease-ontology.org/term/DOID:11724", "evidence": [ { "id": "11724", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11724" } ], "weight": 0.0 } ], "biological_process": [ { "name": "plasma membrane organization", "id": "GO:0007009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007009", "evidence": [ { "database": "UniProtKB", "id": "D4ABP2", "url": "https://www.uniprot.org/uniprotkb/D4ABP2" } ], "pmid": "" } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "D4ABP2", "url": "https://www.uniprot.org/uniprotkb/D4ABP2" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "D4ABP2", "url": "https://www.uniprot.org/uniprotkb/D4ABP2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "D4ABP2-1", "start_pos": "365", "end_pos": "365", "site_lbl": "Thr365", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 365, "start_aa": "Thr", "end_pos": 365, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr365", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "D4ABP2-1" }, { "uniprot_canonical_ac": "D4ABP3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4ABP3", "url": "https://www.uniprot.org/uniprotkb/D4ABP3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 465, "chemical_mass": 53223.0, "gene_names": "Cdr2l;Cdr2l;RGD1306881", "protein_name": "", "disease": [], "molecular_function": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "D4ABP3", "url": "https://www.uniprot.org/uniprotkb/D4ABP3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D4ABP3-1" }, { "uniprot_canonical_ac": "D4ABU0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4ABU0", "url": "https://www.uniprot.org/uniprotkb/D4ABU0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 649, "chemical_mass": 72444.0, "gene_names": "Med17;Crsp6;MED17;Med17", "protein_name": "Mediator of RNA polymerase II transcription subunit 17", "disease": [ { "disease_id": "DOID:0111262", "name": "infantile cerebral and cerebellar atrophy with postnatal progressive microcephaly", "description": "A brain disease characterized by cerebral and cerebellar atrophy, postnatal progressive microcephaly and intellectual disability that has_material_basis_in homozygous or compound heterozygous mutation in MED17 on 11q21.", "url": "https://disease-ontology.org/term/DOID:0111262", "evidence": [ { "id": "0111262", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111262" } ], "weight": 0.0 } ], "biological_process": [ { "name": "positive regulation of transcription initiation by RNA polymerase II", "id": "GO:0060261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060261", "evidence": [ { "database": "UniProtKB", "id": "D4ABU0", "url": "https://www.uniprot.org/uniprotkb/D4ABU0" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "D4ABU0", "url": "https://www.uniprot.org/uniprotkb/D4ABU0" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "D4ABU0", "url": "https://www.uniprot.org/uniprotkb/D4ABU0" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "D4ABU0", "url": "https://www.uniprot.org/uniprotkb/D4ABU0" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "D4ABU0", "url": "https://www.uniprot.org/uniprotkb/D4ABU0" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "D4ABU0", "url": "https://www.uniprot.org/uniprotkb/D4ABU0" } ], "pmid": "" }, { "name": "stem cell population maintenance", "id": "GO:0019827", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019827", "evidence": [ { "database": "UniProtKB", "id": "D4ABU0", "url": "https://www.uniprot.org/uniprotkb/D4ABU0" } ], "pmid": "" } ], "molecular_function": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "D4ABU0", "url": "https://www.uniprot.org/uniprotkb/D4ABU0" } ], "pmid": "" }, { "name": "nuclear thyroid hormone receptor binding", "id": "GO:0046966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046966", "evidence": [ { "database": "UniProtKB", "id": "D4ABU0", "url": "https://www.uniprot.org/uniprotkb/D4ABU0" } ], "pmid": "" }, { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "D4ABU0", "url": "https://www.uniprot.org/uniprotkb/D4ABU0" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D4ABU0", "url": "https://www.uniprot.org/uniprotkb/D4ABU0" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "D4ABU0", "url": "https://www.uniprot.org/uniprotkb/D4ABU0" } ], "pmid": "" }, { "name": "ubiquitin ligase complex", "id": "GO:0000151", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000151", "evidence": [ { "database": "UniProtKB", "id": "D4ABU0", "url": "https://www.uniprot.org/uniprotkb/D4ABU0" } ], "pmid": "" }, { "name": "mediator complex", "id": "GO:0016592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016592", "evidence": [ { "database": "UniProtKB", "id": "D4ABU0", "url": "https://www.uniprot.org/uniprotkb/D4ABU0" } ], "pmid": "" }, { "name": "core mediator complex", "id": "GO:0070847", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070847", "evidence": [ { "database": "UniProtKB", "id": "D4ABU0", "url": "https://www.uniprot.org/uniprotkb/D4ABU0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D4ABU0-1" }, { "uniprot_canonical_ac": "D4ABV2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4ABV2", "url": "https://www.uniprot.org/uniprotkb/D4ABV2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1030, "chemical_mass": 120832.0, "gene_names": "Cep112", "protein_name": "", "disease": [ { "disease_id": "DOID:0112109", "name": "spermatogenic failure 44", "description": "A spermatogenic failure characterized by high prevalence of acephalic sperm and reduced progressive motility of sperm that has_material_basis_in homozygous or compound heterozygous mutation in the CEP112 gene on chromosome 17q24.1.", "url": "https://disease-ontology.org/term/DOID:0112109", "evidence": [ { "id": "0112109", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112109" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "D4ABV2", "url": "https://www.uniprot.org/uniprotkb/D4ABV2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "D4ABV2", "url": "https://www.uniprot.org/uniprotkb/D4ABV2" } ], "pmid": "" }, { "name": "inhibitory synapse", "id": "GO:0060077", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060077", "evidence": [ { "database": "UniProtKB", "id": "D4ABV2", "url": "https://www.uniprot.org/uniprotkb/D4ABV2" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "D4ABV2", "url": "https://www.uniprot.org/uniprotkb/D4ABV2" } ], "pmid": "" }, { "name": "sperm head-tail coupling apparatus", "id": "GO:0120212", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120212", "evidence": [ { "database": "UniProtKB", "id": "D4ABV2", "url": "https://www.uniprot.org/uniprotkb/D4ABV2" } ], "pmid": "" } ], "biological_process": [ { "name": "receptor localization to synapse", "id": "GO:0097120", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097120", "evidence": [ { "database": "UniProtKB", "id": "D4ABV2", "url": "https://www.uniprot.org/uniprotkb/D4ABV2" } ], "pmid": "" }, { "name": "regulation of translation", "id": "GO:0006417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006417", "evidence": [ { "database": "UniProtKB", "id": "D4ABV2", "url": "https://www.uniprot.org/uniprotkb/D4ABV2" } ], "pmid": "" }, { "name": "spermatid development", "id": "GO:0007286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007286", "evidence": [ { "database": "UniProtKB", "id": "D4ABV2", "url": "https://www.uniprot.org/uniprotkb/D4ABV2" } ], "pmid": "" }, { "name": "single fertilization", "id": "GO:0007338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007338", "evidence": [ { "database": "UniProtKB", "id": "D4ABV2", "url": "https://www.uniprot.org/uniprotkb/D4ABV2" } ], "pmid": "" }, { "name": "gene expression", "id": "GO:0010467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010467", "evidence": [ { "database": "UniProtKB", "id": "D4ABV2", "url": "https://www.uniprot.org/uniprotkb/D4ABV2" } ], "pmid": "" } ], "molecular_function": [ { "name": "molecular condensate scaffold activity", "id": "GO:0140693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140693", "evidence": [ { "database": "UniProtKB", "id": "D4ABV2", "url": "https://www.uniprot.org/uniprotkb/D4ABV2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D4ABV2-1" }, { "uniprot_canonical_ac": "D4ACD8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4ACD8", "url": "https://www.uniprot.org/uniprotkb/D4ACD8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 410, "chemical_mass": 46311.0, "gene_names": "Hoxd10", "protein_name": "Homeobox protein Hox-D10", "disease": [ { "disease_id": "DOID:0111568", "name": "congenital vertical talus", "description": "A connective tissue disease characterized by dislocation of the talonavicular joint with vertical orientation of the talus and rigid dorsal dislocation of the navicular, equinus deformity of the calcaneus, abduction deformity of the forefoot, and contracture of the soft tissues of the hind- and mid-foot that has_material_basis_in heterozygous mutation in the HOXD10 gene on chromosome 2q31.1.", "url": "https://disease-ontology.org/term/DOID:0111568", "evidence": [ { "id": "0111568", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111568" } ], "weight": 0.0 } ], "biological_process": [ { "name": "spinal cord motor neuron cell fate specification", "id": "GO:0021520", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021520", "evidence": [ { "database": "UniProtKB", "id": "D4ACD8", "url": "https://www.uniprot.org/uniprotkb/D4ACD8" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "D4ACD8", "url": "https://www.uniprot.org/uniprotkb/D4ACD8" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "D4ACD8", "url": "https://www.uniprot.org/uniprotkb/D4ACD8" } ], "pmid": "" }, { "name": "adult locomotory behavior", "id": "GO:0008344", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008344", "evidence": [ { "database": "UniProtKB", "id": "D4ACD8", "url": "https://www.uniprot.org/uniprotkb/D4ACD8" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "D4ACD8", "url": "https://www.uniprot.org/uniprotkb/D4ACD8" } ], "pmid": "" }, { "name": "neuromuscular process", "id": "GO:0050905", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050905", "evidence": [ { "database": "UniProtKB", "id": "D4ACD8", "url": "https://www.uniprot.org/uniprotkb/D4ACD8" } ], "pmid": "" }, { "name": "single fertilization", "id": "GO:0007338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007338", "evidence": [ { "database": "UniProtKB", "id": "D4ACD8", "url": "https://www.uniprot.org/uniprotkb/D4ACD8" } ], "pmid": "" }, { "name": "skeletal system development", "id": "GO:0001501", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001501", "evidence": [ { "database": "UniProtKB", "id": "D4ACD8", "url": "https://www.uniprot.org/uniprotkb/D4ACD8" } ], "pmid": "" }, { "name": "embryonic limb morphogenesis", "id": "GO:0030326", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030326", "evidence": [ { "database": "UniProtKB", "id": "D4ACD8", "url": "https://www.uniprot.org/uniprotkb/D4ACD8" } ], "pmid": "" }, { "name": "anterior/posterior pattern specification", "id": "GO:0009952", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009952", "evidence": [ { "database": "UniProtKB", "id": "D4ACD8", "url": "https://www.uniprot.org/uniprotkb/D4ACD8" } ], "pmid": "" }, { "name": "proximal/distal pattern formation", "id": "GO:0009954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009954", "evidence": [ { "database": "UniProtKB", "id": "D4ACD8", "url": "https://www.uniprot.org/uniprotkb/D4ACD8" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "D4ACD8", "url": "https://www.uniprot.org/uniprotkb/D4ACD8" } ], "pmid": "" }, { "name": "embryonic skeletal system morphogenesis", "id": "GO:0048704", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048704", "evidence": [ { "database": "UniProtKB", "id": "D4ACD8", "url": "https://www.uniprot.org/uniprotkb/D4ACD8" } ], "pmid": "" }, { "name": "forelimb morphogenesis", "id": "GO:0035136", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035136", "evidence": [ { "database": "UniProtKB", "id": "D4ACD8", "url": "https://www.uniprot.org/uniprotkb/D4ACD8" } ], "pmid": "" }, { "name": "hindlimb morphogenesis", "id": "GO:0035137", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035137", "evidence": [ { "database": "UniProtKB", "id": "D4ACD8", "url": "https://www.uniprot.org/uniprotkb/D4ACD8" } ], "pmid": "" }, { "name": "skeletal muscle tissue development", "id": "GO:0007519", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007519", "evidence": [ { "database": "UniProtKB", "id": "D4ACD8", "url": "https://www.uniprot.org/uniprotkb/D4ACD8" } ], "pmid": "" }, { "name": "peripheral nervous system neuron development", "id": "GO:0048935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048935", "evidence": [ { "database": "UniProtKB", "id": "D4ACD8", "url": "https://www.uniprot.org/uniprotkb/D4ACD8" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "D4ACD8", "url": "https://www.uniprot.org/uniprotkb/D4ACD8" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "D4ACD8", "url": "https://www.uniprot.org/uniprotkb/D4ACD8" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "D4ACD8", "url": "https://www.uniprot.org/uniprotkb/D4ACD8" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "D4ACD8", "url": "https://www.uniprot.org/uniprotkb/D4ACD8" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "D4ACD8", "url": "https://www.uniprot.org/uniprotkb/D4ACD8" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "D4ACD8", "url": "https://www.uniprot.org/uniprotkb/D4ACD8" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "D4ACD8", "url": "https://www.uniprot.org/uniprotkb/D4ACD8" } ], "pmid": "" }, { "name": "sequence-specific double-stranded DNA binding", "id": "GO:1990837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990837", "evidence": [ { "database": "UniProtKB", "id": "D4ACD8", "url": "https://www.uniprot.org/uniprotkb/D4ACD8" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D4ACD8", "url": "https://www.uniprot.org/uniprotkb/D4ACD8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D4ACD8-1" }, { "uniprot_canonical_ac": "D4ACL0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4ACL0", "url": "https://www.uniprot.org/uniprotkb/D4ACL0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 304, "chemical_mass": 33708.0, "gene_names": "Hoxc11;Hoxc11;LOC100911859;RGD1305450", "protein_name": "", "disease": [], "biological_process": [ { "name": "organ induction", "id": "GO:0001759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001759", "evidence": [ { "database": "UniProtKB", "id": "D4ACL0", "url": "https://www.uniprot.org/uniprotkb/D4ACL0" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "D4ACL0", "url": "https://www.uniprot.org/uniprotkb/D4ACL0" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "D4ACL0", "url": "https://www.uniprot.org/uniprotkb/D4ACL0" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "D4ACL0", "url": "https://www.uniprot.org/uniprotkb/D4ACL0" } ], "pmid": "" }, { "name": "skeletal system development", "id": "GO:0001501", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001501", "evidence": [ { "database": "UniProtKB", "id": "D4ACL0", "url": "https://www.uniprot.org/uniprotkb/D4ACL0" } ], "pmid": "" }, { "name": "anterior/posterior pattern specification", "id": "GO:0009952", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009952", "evidence": [ { "database": "UniProtKB", "id": "D4ACL0", "url": "https://www.uniprot.org/uniprotkb/D4ACL0" } ], "pmid": "" }, { "name": "proximal/distal pattern formation", "id": "GO:0009954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009954", "evidence": [ { "database": "UniProtKB", "id": "D4ACL0", "url": "https://www.uniprot.org/uniprotkb/D4ACL0" } ], "pmid": "" }, { "name": "embryonic digit morphogenesis", "id": "GO:0042733", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042733", "evidence": [ { "database": "UniProtKB", "id": "D4ACL0", "url": "https://www.uniprot.org/uniprotkb/D4ACL0" } ], "pmid": "" }, { "name": "metanephros development", "id": "GO:0001656", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001656", "evidence": [ { "database": "UniProtKB", "id": "D4ACL0", "url": "https://www.uniprot.org/uniprotkb/D4ACL0" } ], "pmid": "" }, { "name": "embryonic skeletal joint morphogenesis", "id": "GO:0060272", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060272", "evidence": [ { "database": "UniProtKB", "id": "D4ACL0", "url": "https://www.uniprot.org/uniprotkb/D4ACL0" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D4ACL0", "url": "https://www.uniprot.org/uniprotkb/D4ACL0" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "D4ACL0", "url": "https://www.uniprot.org/uniprotkb/D4ACL0" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "D4ACL0", "url": "https://www.uniprot.org/uniprotkb/D4ACL0" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "D4ACL0", "url": "https://www.uniprot.org/uniprotkb/D4ACL0" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "D4ACL0", "url": "https://www.uniprot.org/uniprotkb/D4ACL0" } ], "pmid": "" }, { "name": "sequence-specific double-stranded DNA binding", "id": "GO:1990837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990837", "evidence": [ { "database": "UniProtKB", "id": "D4ACL0", "url": "https://www.uniprot.org/uniprotkb/D4ACL0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D4ACL0-1" }, { "uniprot_canonical_ac": "D4ACN5-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4ACN5", "url": "https://www.uniprot.org/uniprotkb/D4ACN5" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1668, "chemical_mass": 190598.0, "gene_names": "Abca15;Abca15", "protein_name": "", "disease": [ { "disease_id": "DOID:0060041", "name": "autism spectrum disorder", "description": "A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior.", "url": "https://disease-ontology.org/term/DOID:0060041", "evidence": [ { "id": "0060041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060041" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "lipid transporter activity", "id": "GO:0005319", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005319", "evidence": [ { "database": "UniProtKB", "id": "D4ACN5", "url": "https://www.uniprot.org/uniprotkb/D4ACN5" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "D4ACN5", "url": "https://www.uniprot.org/uniprotkb/D4ACN5" } ], "pmid": "" }, { "name": "ATPase-coupled transmembrane transporter activity", "id": "GO:0042626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042626", "evidence": [ { "database": "UniProtKB", "id": "D4ACN5", "url": "https://www.uniprot.org/uniprotkb/D4ACN5" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "D4ACN5", "url": "https://www.uniprot.org/uniprotkb/D4ACN5" } ], "pmid": "" }, { "name": "ABC-type transporter activity", "id": "GO:0140359", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140359", "evidence": [ { "database": "UniProtKB", "id": "D4ACN5", "url": "https://www.uniprot.org/uniprotkb/D4ACN5" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "D4ACN5", "url": "https://www.uniprot.org/uniprotkb/D4ACN5" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "D4ACN5", "url": "https://www.uniprot.org/uniprotkb/D4ACN5" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "D4ACN5", "url": "https://www.uniprot.org/uniprotkb/D4ACN5" } ], "pmid": "" } ], "biological_process": [ { "name": "lipid transport", "id": "GO:0006869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006869", "evidence": [ { "database": "UniProtKB", "id": "D4ACN5", "url": "https://www.uniprot.org/uniprotkb/D4ACN5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "D4ACN5-1", "start_pos": "1409", "end_pos": "1409", "site_lbl": "Thr1409", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1409, "start_aa": "Thr", "end_pos": 1409, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1409", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "D4ACN5-1" }, { "uniprot_canonical_ac": "D4ACR8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4ACR8", "url": "https://www.uniprot.org/uniprotkb/D4ACR8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 272, "chemical_mass": 30795.0, "gene_names": "E2f6;E2f6", "protein_name": "", "disease": [ { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 } ], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "D4ACR8", "url": "https://www.uniprot.org/uniprotkb/D4ACR8" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "D4ACR8", "url": "https://www.uniprot.org/uniprotkb/D4ACR8" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "D4ACR8", "url": "https://www.uniprot.org/uniprotkb/D4ACR8" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "D4ACR8", "url": "https://www.uniprot.org/uniprotkb/D4ACR8" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "D4ACR8", "url": "https://www.uniprot.org/uniprotkb/D4ACR8" } ], "pmid": "" }, { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "D4ACR8", "url": "https://www.uniprot.org/uniprotkb/D4ACR8" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "D4ACR8", "url": "https://www.uniprot.org/uniprotkb/D4ACR8" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "D4ACR8", "url": "https://www.uniprot.org/uniprotkb/D4ACR8" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "D4ACR8", "url": "https://www.uniprot.org/uniprotkb/D4ACR8" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "D4ACR8", "url": "https://www.uniprot.org/uniprotkb/D4ACR8" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D4ACR8", "url": "https://www.uniprot.org/uniprotkb/D4ACR8" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "D4ACR8", "url": "https://www.uniprot.org/uniprotkb/D4ACR8" } ], "pmid": "" }, { "name": "MLL1 complex", "id": "GO:0071339", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071339", "evidence": [ { "database": "UniProtKB", "id": "D4ACR8", "url": "https://www.uniprot.org/uniprotkb/D4ACR8" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulator complex", "id": "GO:0090575", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090575", "evidence": [ { "database": "UniProtKB", "id": "D4ACR8", "url": "https://www.uniprot.org/uniprotkb/D4ACR8" } ], "pmid": "" }, { "name": "RNA polymerase II transcription repressor complex", "id": "GO:0090571", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090571", "evidence": [ { "database": "UniProtKB", "id": "D4ACR8", "url": "https://www.uniprot.org/uniprotkb/D4ACR8" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "D4ACR8", "url": "https://www.uniprot.org/uniprotkb/D4ACR8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D4ACR8-1" }, { "uniprot_canonical_ac": "D4AD19-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4AD19", "url": "https://www.uniprot.org/uniprotkb/D4AD19" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 254, "chemical_mass": 26789.0, "gene_names": "Cimap1b;Odf3b", "protein_name": "", "disease": [], "cellular_component": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "D4AD19", "url": "https://www.uniprot.org/uniprotkb/D4AD19" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D4AD19-1" }, { "uniprot_canonical_ac": "D4AD91-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4AD91", "url": "https://www.uniprot.org/uniprotkb/D4AD91" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 902, "chemical_mass": 100583.0, "gene_names": "C4h3orf20;C4h3orf20;RGD1560289", "protein_name": "", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "D4AD91", "url": "https://www.uniprot.org/uniprotkb/D4AD91" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "D4AD91-1", "start_pos": "62", "end_pos": "62", "site_lbl": "Thr62", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 62, "start_aa": "Thr", "end_pos": 62, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr62", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "D4AD91-1" }, { "uniprot_canonical_ac": "D4AD99-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4AD99", "url": "https://www.uniprot.org/uniprotkb/D4AD99" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 779, "chemical_mass": 85669.0, "gene_names": "Cpeb3;Cpeb3;RGD1564670", "protein_name": "", "disease": [], "cellular_component": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "D4AD99", "url": "https://www.uniprot.org/uniprotkb/D4AD99" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D4AD99", "url": "https://www.uniprot.org/uniprotkb/D4AD99" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "D4AD99", "url": "https://www.uniprot.org/uniprotkb/D4AD99" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "D4AD99", "url": "https://www.uniprot.org/uniprotkb/D4AD99" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "D4AD99", "url": "https://www.uniprot.org/uniprotkb/D4AD99" } ], "pmid": "" }, { "name": "postsynapse", "id": "GO:0098794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098794", "evidence": [ { "database": "UniProtKB", "id": "D4AD99", "url": "https://www.uniprot.org/uniprotkb/D4AD99" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "D4AD99", "url": "https://www.uniprot.org/uniprotkb/D4AD99" } ], "pmid": "" }, { "name": "CCR4-NOT complex", "id": "GO:0030014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030014", "evidence": [ { "database": "UniProtKB", "id": "D4AD99", "url": "https://www.uniprot.org/uniprotkb/D4AD99" } ], "pmid": "" }, { "name": "apical dendrite", "id": "GO:0097440", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097440", "evidence": [ { "database": "UniProtKB", "id": "D4AD99", "url": "https://www.uniprot.org/uniprotkb/D4AD99" } ], "pmid": "" } ], "molecular_function": [ { "name": "mRNA regulatory element binding translation repressor activity", "id": "GO:0000900", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000900", "evidence": [ { "database": "UniProtKB", "id": "D4AD99", "url": "https://www.uniprot.org/uniprotkb/D4AD99" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "D4AD99", "url": "https://www.uniprot.org/uniprotkb/D4AD99" } ], "pmid": "" }, { "name": "translation factor activity, RNA binding", "id": "GO:0008135", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008135", "evidence": [ { "database": "UniProtKB", "id": "D4AD99", "url": "https://www.uniprot.org/uniprotkb/D4AD99" } ], "pmid": "" }, { "name": "ribosome binding", "id": "GO:0043022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043022", "evidence": [ { "database": "UniProtKB", "id": "D4AD99", "url": "https://www.uniprot.org/uniprotkb/D4AD99" } ], "pmid": "" }, { "name": "mRNA 3'-UTR binding", "id": "GO:0003730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003730", "evidence": [ { "database": "UniProtKB", "id": "D4AD99", "url": "https://www.uniprot.org/uniprotkb/D4AD99" } ], "pmid": "" }, { "name": "RNA stem-loop binding", "id": "GO:0035613", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035613", "evidence": [ { "database": "UniProtKB", "id": "D4AD99", "url": "https://www.uniprot.org/uniprotkb/D4AD99" } ], "pmid": "" }, { "name": "mRNA 3'-UTR AU-rich region binding", "id": "GO:0035925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035925", "evidence": [ { "database": "UniProtKB", "id": "D4AD99", "url": "https://www.uniprot.org/uniprotkb/D4AD99" } ], "pmid": "" }, { "name": "translation regulator activity", "id": "GO:0045182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045182", "evidence": [ { "database": "UniProtKB", "id": "D4AD99", "url": "https://www.uniprot.org/uniprotkb/D4AD99" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "D4AD99", "url": "https://www.uniprot.org/uniprotkb/D4AD99" } ], "pmid": "" }, { "name": "positive regulation of long-term synaptic potentiation", "id": "GO:1900273", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900273", "evidence": [ { "database": "UniProtKB", "id": "D4AD99", "url": "https://www.uniprot.org/uniprotkb/D4AD99" } ], "pmid": "" }, { "name": "regulation of synaptic plasticity", "id": "GO:0048167", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048167", "evidence": [ { "database": "UniProtKB", "id": "D4AD99", "url": "https://www.uniprot.org/uniprotkb/D4AD99" } ], "pmid": "" }, { "name": "negative regulation of translation", "id": "GO:0017148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017148", "evidence": [ { "database": "UniProtKB", "id": "D4AD99", "url": "https://www.uniprot.org/uniprotkb/D4AD99" } ], "pmid": "" }, { "name": "positive regulation of translation", "id": "GO:0045727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045727", "evidence": [ { "database": "UniProtKB", "id": "D4AD99", "url": "https://www.uniprot.org/uniprotkb/D4AD99" } ], "pmid": "" }, { "name": "long-term memory", "id": "GO:0007616", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007616", "evidence": [ { "database": "UniProtKB", "id": "D4AD99", "url": "https://www.uniprot.org/uniprotkb/D4AD99" } ], "pmid": "" }, { "name": "positive regulation of nuclear-transcribed mRNA poly(A) tail shortening", "id": "GO:0060213", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060213", "evidence": [ { "database": "UniProtKB", "id": "D4AD99", "url": "https://www.uniprot.org/uniprotkb/D4AD99" } ], "pmid": "" }, { "name": "positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay", "id": "GO:1900153", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900153", "evidence": [ { "database": "UniProtKB", "id": "D4AD99", "url": "https://www.uniprot.org/uniprotkb/D4AD99" } ], "pmid": "" }, { "name": "regulation of dendritic spine development", "id": "GO:0060998", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060998", "evidence": [ { "database": "UniProtKB", "id": "D4AD99", "url": "https://www.uniprot.org/uniprotkb/D4AD99" } ], "pmid": "" }, { "name": "positive regulation of dendritic spine development", "id": "GO:0060999", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060999", "evidence": [ { "database": "UniProtKB", "id": "D4AD99", "url": "https://www.uniprot.org/uniprotkb/D4AD99" } ], "pmid": "" }, { "name": "cellular response to amino acid stimulus", "id": "GO:0071230", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071230", "evidence": [ { "database": "UniProtKB", "id": "D4AD99", "url": "https://www.uniprot.org/uniprotkb/D4AD99" } ], "pmid": "" }, { "name": "3'-UTR-mediated mRNA destabilization", "id": "GO:0061158", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061158", "evidence": [ { "database": "UniProtKB", "id": "D4AD99", "url": "https://www.uniprot.org/uniprotkb/D4AD99" } ], "pmid": "" }, { "name": "negative regulation of cytoplasmic translational elongation", "id": "GO:1900248", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900248", "evidence": [ { "database": "UniProtKB", "id": "D4AD99", "url": "https://www.uniprot.org/uniprotkb/D4AD99" } ], "pmid": "" }, { "name": "negative regulation of cytoplasmic translation", "id": "GO:2000766", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000766", "evidence": [ { "database": "UniProtKB", "id": "D4AD99", "url": "https://www.uniprot.org/uniprotkb/D4AD99" } ], "pmid": "" }, { "name": "thermoception", "id": "GO:0050955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050955", "evidence": [ { "database": "UniProtKB", "id": "D4AD99", "url": "https://www.uniprot.org/uniprotkb/D4AD99" } ], "pmid": "" }, { "name": "regulation of postsynapse assembly", "id": "GO:0150052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0150052", "evidence": [ { "database": "UniProtKB", "id": "D4AD99", "url": "https://www.uniprot.org/uniprotkb/D4AD99" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D4AD99-1" }, { "uniprot_canonical_ac": "D4ADI3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4ADI3", "url": "https://www.uniprot.org/uniprotkb/D4ADI3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 340, "chemical_mass": 38055.0, "gene_names": "Klf17;Klf17;Zfp393", "protein_name": "Krueppel-like factor 17", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D4ADI3", "url": "https://www.uniprot.org/uniprotkb/D4ADI3" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "D4ADI3", "url": "https://www.uniprot.org/uniprotkb/D4ADI3" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "D4ADI3", "url": "https://www.uniprot.org/uniprotkb/D4ADI3" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "D4ADI3", "url": "https://www.uniprot.org/uniprotkb/D4ADI3" } ], "pmid": "" }, { "name": "gamete generation", "id": "GO:0007276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007276", "evidence": [ { "database": "UniProtKB", "id": "D4ADI3", "url": "https://www.uniprot.org/uniprotkb/D4ADI3" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "D4ADI3", "url": "https://www.uniprot.org/uniprotkb/D4ADI3" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "D4ADI3", "url": "https://www.uniprot.org/uniprotkb/D4ADI3" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "D4ADI3", "url": "https://www.uniprot.org/uniprotkb/D4ADI3" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "D4ADI3", "url": "https://www.uniprot.org/uniprotkb/D4ADI3" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "D4ADI3", "url": "https://www.uniprot.org/uniprotkb/D4ADI3" } ], "pmid": "" }, { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "D4ADI3", "url": "https://www.uniprot.org/uniprotkb/D4ADI3" } ], "pmid": "" }, { "name": "sequence-specific double-stranded DNA binding", "id": "GO:1990837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990837", "evidence": [ { "database": "UniProtKB", "id": "D4ADI3", "url": "https://www.uniprot.org/uniprotkb/D4ADI3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "D4ADI3-1", "start_pos": "154", "end_pos": "154", "site_lbl": "Thr154", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 154, "start_aa": "Thr", "end_pos": 154, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr154", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "D4ADI3-1", "start_pos": "229", "end_pos": "229", "site_lbl": "Thr229", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 229, "start_aa": "Thr", "end_pos": 229, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr229", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "D4ADI3-1" }, { "uniprot_canonical_ac": "D4ADK2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4ADK2", "url": "https://www.uniprot.org/uniprotkb/D4ADK2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 333, "chemical_mass": 37211.0, "gene_names": "Or10a3", "protein_name": "Olfactory receptor", "disease": [ { "disease_id": "DOID:0060980", "name": "polycystic liver disease 1", "description": "A polycystic disease characterized by the presence of multiple liver cysts of biliary epithelial origin that has_material_basis_in heterozygous mutation in the PRKCSH gene on chromosome 19p13.", "url": "https://disease-ontology.org/term/DOID:0060980", "evidence": [ { "id": "0060980", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060980" } ], "weight": 0.0 }, { "disease_id": "DOID:0080322", "name": "polycystic kidney disease", "description": "A cystic kidney disease that is characterized by the growth of fluid-filled cysts in the kidneys that reduces kidney function and may lead to kidney failure.", "url": "https://disease-ontology.org/term/DOID:0080322", "evidence": [ { "id": "0080322", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080322" } ], "weight": 0.0 }, { "disease_id": "DOID:0112106", "name": "chondrodysplasia with platyspondyly, distinctive brachydactyly, hydrocephaly, and microphthalmia", "description": "A syndrome characterized by chondrodysplasia associated with other features including intrauterine growth retardation, hydrocephaly, macrocephaly, frontal bossing, microphthalmia, small low-set ears, and short flat nose that has_material_basis_in heterozygous mutation in the HDAC6 gene on chromosome Xp11.23.", "url": "https://disease-ontology.org/term/DOID:0112106", "evidence": [ { "id": "0112106", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112106" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:14330", "name": "Parkinson's disease", "description": "A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.", "url": "https://disease-ontology.org/term/DOID:14330", "evidence": [ { "id": "14330", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14330" } ], "weight": 0.0 }, { "disease_id": "DOID:4947", "name": "cholangiocarcinoma", "description": "A bile duct adenocarcinoma that has_material_basis_in bile duct epithelial cells.", "url": "https://disease-ontology.org/term/DOID:4947", "evidence": [ { "id": "4947", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4947" } ], "weight": 0.0 }, { "disease_id": "DOID:8991", "name": "cervix uteri carcinoma in situ", "description": "An uterus carcinoma in situ that is located_in the uterine cervix.", "url": "https://disease-ontology.org/term/DOID:8991", "evidence": [ { "id": "8991", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8991" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "D4ADK2", "url": "https://www.uniprot.org/uniprotkb/D4ADK2" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "D4ADK2", "url": "https://www.uniprot.org/uniprotkb/D4ADK2" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "D4ADK2", "url": "https://www.uniprot.org/uniprotkb/D4ADK2" } ], "pmid": "" } ], "biological_process": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "D4ADK2", "url": "https://www.uniprot.org/uniprotkb/D4ADK2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D4ADK2-1" }, { "uniprot_canonical_ac": "D4ADQ2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4ADQ2", "url": "https://www.uniprot.org/uniprotkb/D4ADQ2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 222, "chemical_mass": 25128.0, "gene_names": "Pld6;Pld6;RGD1311987", "protein_name": "Mitochondrial cardiolipin hydrolase", "disease": [], "molecular_function": [ { "name": "phospholipase D activity", "id": "GO:0004630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004630", "evidence": [ { "database": "UniProtKB", "id": "D4ADQ2", "url": "https://www.uniprot.org/uniprotkb/D4ADQ2" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "D4ADQ2", "url": "https://www.uniprot.org/uniprotkb/D4ADQ2" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "D4ADQ2", "url": "https://www.uniprot.org/uniprotkb/D4ADQ2" } ], "pmid": "" }, { "name": "RNA endonuclease activity producing 5'-phosphomonoesters, hydrolytic mechanism", "id": "GO:0016891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016891", "evidence": [ { "database": "UniProtKB", "id": "D4ADQ2", "url": "https://www.uniprot.org/uniprotkb/D4ADQ2" } ], "pmid": "" }, { "name": "cardiolipin hydrolase activity", "id": "GO:0035755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035755", "evidence": [ { "database": "UniProtKB", "id": "D4ADQ2", "url": "https://www.uniprot.org/uniprotkb/D4ADQ2" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "D4ADQ2", "url": "https://www.uniprot.org/uniprotkb/D4ADQ2" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "D4ADQ2", "url": "https://www.uniprot.org/uniprotkb/D4ADQ2" } ], "pmid": "" }, { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "D4ADQ2", "url": "https://www.uniprot.org/uniprotkb/D4ADQ2" } ], "pmid": "" } ], "biological_process": [ { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "D4ADQ2", "url": "https://www.uniprot.org/uniprotkb/D4ADQ2" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "D4ADQ2", "url": "https://www.uniprot.org/uniprotkb/D4ADQ2" } ], "pmid": "" }, { "name": "lipid catabolic process", "id": "GO:0016042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016042", "evidence": [ { "database": "UniProtKB", "id": "D4ADQ2", "url": "https://www.uniprot.org/uniprotkb/D4ADQ2" } ], "pmid": "" }, { "name": "piRNA processing", "id": "GO:0034587", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034587", "evidence": [ { "database": "UniProtKB", "id": "D4ADQ2", "url": "https://www.uniprot.org/uniprotkb/D4ADQ2" } ], "pmid": "" }, { "name": "meiotic cell cycle", "id": "GO:0051321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051321", "evidence": [ { "database": "UniProtKB", "id": "D4ADQ2", "url": "https://www.uniprot.org/uniprotkb/D4ADQ2" } ], "pmid": "" }, { "name": "positive regulation of mitochondrial fusion", "id": "GO:0010636", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010636", "evidence": [ { "database": "UniProtKB", "id": "D4ADQ2", "url": "https://www.uniprot.org/uniprotkb/D4ADQ2" } ], "pmid": "" }, { "name": "P granule organization", "id": "GO:0030719", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030719", "evidence": [ { "database": "UniProtKB", "id": "D4ADQ2", "url": "https://www.uniprot.org/uniprotkb/D4ADQ2" } ], "pmid": "" }, { "name": "spermatid development", "id": "GO:0007286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007286", "evidence": [ { "database": "UniProtKB", "id": "D4ADQ2", "url": "https://www.uniprot.org/uniprotkb/D4ADQ2" } ], "pmid": "" }, { "name": "mitochondrial fusion", "id": "GO:0008053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008053", "evidence": [ { "database": "UniProtKB", "id": "D4ADQ2", "url": "https://www.uniprot.org/uniprotkb/D4ADQ2" } ], "pmid": "" }, { "name": "phospholipid biosynthetic process", "id": "GO:0008654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008654", "evidence": [ { "database": "UniProtKB", "id": "D4ADQ2", "url": "https://www.uniprot.org/uniprotkb/D4ADQ2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D4ADQ2-1" }, { "uniprot_canonical_ac": "D4ADT3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4ADT3", "url": "https://www.uniprot.org/uniprotkb/D4ADT3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1198, "chemical_mass": 133720.0, "gene_names": "Wapl;RGD1308960;Wapal;Wapl", "protein_name": "Wings apart-like protein homolog", "disease": [], "biological_process": [ { "name": "negative regulation of sister chromatid cohesion", "id": "GO:0045875", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045875", "evidence": [ { "database": "UniProtKB", "id": "D4ADT3", "url": "https://www.uniprot.org/uniprotkb/D4ADT3" } ], "pmid": "" }, { "name": "meiotic chromosome separation", "id": "GO:0051307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051307", "evidence": [ { "database": "UniProtKB", "id": "D4ADT3", "url": "https://www.uniprot.org/uniprotkb/D4ADT3" } ], "pmid": "" }, { "name": "mitotic cell cycle", "id": "GO:0000278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000278", "evidence": [ { "database": "UniProtKB", "id": "D4ADT3", "url": "https://www.uniprot.org/uniprotkb/D4ADT3" } ], "pmid": "" }, { "name": "attachment of spindle microtubules to kinetochore", "id": "GO:0008608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008608", "evidence": [ { "database": "UniProtKB", "id": "D4ADT3", "url": "https://www.uniprot.org/uniprotkb/D4ADT3" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "D4ADT3", "url": "https://www.uniprot.org/uniprotkb/D4ADT3" } ], "pmid": "" }, { "name": "response to toxic substance", "id": "GO:0009636", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009636", "evidence": [ { "database": "UniProtKB", "id": "D4ADT3", "url": "https://www.uniprot.org/uniprotkb/D4ADT3" } ], "pmid": "" }, { "name": "positive regulation of translation", "id": "GO:0045727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045727", "evidence": [ { "database": "UniProtKB", "id": "D4ADT3", "url": "https://www.uniprot.org/uniprotkb/D4ADT3" } ], "pmid": "" }, { "name": "positive regulation of fibroblast proliferation", "id": "GO:0048146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048146", "evidence": [ { "database": "UniProtKB", "id": "D4ADT3", "url": "https://www.uniprot.org/uniprotkb/D4ADT3" } ], "pmid": "" }, { "name": "regulation of meiotic cell cycle", "id": "GO:0051445", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051445", "evidence": [ { "database": "UniProtKB", "id": "D4ADT3", "url": "https://www.uniprot.org/uniprotkb/D4ADT3" } ], "pmid": "" }, { "name": "homologous chromosome pairing at meiosis", "id": "GO:0007129", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007129", "evidence": [ { "database": "UniProtKB", "id": "D4ADT3", "url": "https://www.uniprot.org/uniprotkb/D4ADT3" } ], "pmid": "" }, { "name": "mitotic sister chromatid segregation", "id": "GO:0000070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000070", "evidence": [ { "database": "UniProtKB", "id": "D4ADT3", "url": "https://www.uniprot.org/uniprotkb/D4ADT3" } ], "pmid": "" }, { "name": "regulation of chromosome segregation", "id": "GO:0051983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051983", "evidence": [ { "database": "UniProtKB", "id": "D4ADT3", "url": "https://www.uniprot.org/uniprotkb/D4ADT3" } ], "pmid": "" }, { "name": "negative regulation of DNA replication", "id": "GO:0008156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008156", "evidence": [ { "database": "UniProtKB", "id": "D4ADT3", "url": "https://www.uniprot.org/uniprotkb/D4ADT3" } ], "pmid": "" }, { "name": "protein localization to chromatin", "id": "GO:0071168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071168", "evidence": [ { "database": "UniProtKB", "id": "D4ADT3", "url": "https://www.uniprot.org/uniprotkb/D4ADT3" } ], "pmid": "" }, { "name": "regulation of chromosome condensation", "id": "GO:0060623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060623", "evidence": [ { "database": "UniProtKB", "id": "D4ADT3", "url": "https://www.uniprot.org/uniprotkb/D4ADT3" } ], "pmid": "" }, { "name": "spindle assembly involved in female meiosis", "id": "GO:0007056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007056", "evidence": [ { "database": "UniProtKB", "id": "D4ADT3", "url": "https://www.uniprot.org/uniprotkb/D4ADT3" } ], "pmid": "" }, { "name": "chromatin looping", "id": "GO:0140588", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140588", "evidence": [ { "database": "UniProtKB", "id": "D4ADT3", "url": "https://www.uniprot.org/uniprotkb/D4ADT3" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D4ADT3", "url": "https://www.uniprot.org/uniprotkb/D4ADT3" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "D4ADT3", "url": "https://www.uniprot.org/uniprotkb/D4ADT3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "D4ADT3", "url": "https://www.uniprot.org/uniprotkb/D4ADT3" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "D4ADT3", "url": "https://www.uniprot.org/uniprotkb/D4ADT3" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "D4ADT3", "url": "https://www.uniprot.org/uniprotkb/D4ADT3" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "D4ADT3", "url": "https://www.uniprot.org/uniprotkb/D4ADT3" } ], "pmid": "" }, { "name": "germinal vesicle", "id": "GO:0042585", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042585", "evidence": [ { "database": "UniProtKB", "id": "D4ADT3", "url": "https://www.uniprot.org/uniprotkb/D4ADT3" } ], "pmid": "" }, { "name": "synaptonemal complex", "id": "GO:0000795", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000795", "evidence": [ { "database": "UniProtKB", "id": "D4ADT3", "url": "https://www.uniprot.org/uniprotkb/D4ADT3" } ], "pmid": "" } ], "molecular_function": [ { "name": "ATP-dependent protein-DNA unloader activity", "id": "GO:0140083", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140083", "evidence": [ { "database": "UniProtKB", "id": "D4ADT3", "url": "https://www.uniprot.org/uniprotkb/D4ADT3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D4ADT3-1" }, { "uniprot_canonical_ac": "D4AE85-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4AE85", "url": "https://www.uniprot.org/uniprotkb/D4AE85" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 380, "chemical_mass": 42152.0, "gene_names": "Vash1;RGD1564082;Vash1", "protein_name": "", "disease": [ { "disease_id": "DOID:10762", "name": "portal hypertension", "description": "", "url": "https://disease-ontology.org/term/DOID:10762", "evidence": [ { "id": "10762", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10762" } ], "weight": 0.0 }, { "disease_id": "DOID:5082", "name": "liver cirrhosis", "description": "", "url": "https://disease-ontology.org/term/DOID:5082", "evidence": [ { "id": "5082", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5082" } ], "weight": 0.0 } ], "biological_process": [ { "name": "negative regulation of lymphangiogenesis", "id": "GO:1901491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901491", "evidence": [ { "database": "UniProtKB", "id": "D4AE85", "url": "https://www.uniprot.org/uniprotkb/D4AE85" } ], "pmid": "" }, { "name": "angiogenesis", "id": "GO:0001525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001525", "evidence": [ { "database": "UniProtKB", "id": "D4AE85", "url": "https://www.uniprot.org/uniprotkb/D4AE85" } ], "pmid": "" }, { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "D4AE85", "url": "https://www.uniprot.org/uniprotkb/D4AE85" } ], "pmid": "" }, { "name": "response to wounding", "id": "GO:0009611", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009611", "evidence": [ { "database": "UniProtKB", "id": "D4AE85", "url": "https://www.uniprot.org/uniprotkb/D4AE85" } ], "pmid": "" }, { "name": "negative regulation of endothelial cell proliferation", "id": "GO:0001937", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001937", "evidence": [ { "database": "UniProtKB", "id": "D4AE85", "url": "https://www.uniprot.org/uniprotkb/D4AE85" } ], "pmid": "" }, { "name": "negative regulation of blood vessel endothelial cell migration", "id": "GO:0043537", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043537", "evidence": [ { "database": "UniProtKB", "id": "D4AE85", "url": "https://www.uniprot.org/uniprotkb/D4AE85" } ], "pmid": "" }, { "name": "negative regulation of angiogenesis", "id": "GO:0016525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016525", "evidence": [ { "database": "UniProtKB", "id": "D4AE85", "url": "https://www.uniprot.org/uniprotkb/D4AE85" } ], "pmid": "" }, { "name": "regulation of angiogenesis", "id": "GO:0045765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045765", "evidence": [ { "database": "UniProtKB", "id": "D4AE85", "url": "https://www.uniprot.org/uniprotkb/D4AE85" } ], "pmid": "" }, { "name": "labyrinthine layer blood vessel development", "id": "GO:0060716", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060716", "evidence": [ { "database": "UniProtKB", "id": "D4AE85", "url": "https://www.uniprot.org/uniprotkb/D4AE85" } ], "pmid": "" }, { "name": "placenta blood vessel development", "id": "GO:0060674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060674", "evidence": [ { "database": "UniProtKB", "id": "D4AE85", "url": "https://www.uniprot.org/uniprotkb/D4AE85" } ], "pmid": "" }, { "name": "regulation of cellular senescence", "id": "GO:2000772", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000772", "evidence": [ { "database": "UniProtKB", "id": "D4AE85", "url": "https://www.uniprot.org/uniprotkb/D4AE85" } ], "pmid": "" } ], "molecular_function": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "D4AE85", "url": "https://www.uniprot.org/uniprotkb/D4AE85" } ], "pmid": "" }, { "name": "metallocarboxypeptidase activity", "id": "GO:0004181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004181", "evidence": [ { "database": "UniProtKB", "id": "D4AE85", "url": "https://www.uniprot.org/uniprotkb/D4AE85" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "D4AE85", "url": "https://www.uniprot.org/uniprotkb/D4AE85" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "D4AE85", "url": "https://www.uniprot.org/uniprotkb/D4AE85" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "D4AE85", "url": "https://www.uniprot.org/uniprotkb/D4AE85" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "D4AE85", "url": "https://www.uniprot.org/uniprotkb/D4AE85" } ], "pmid": "" }, { "name": "apical part of cell", "id": "GO:0045177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045177", "evidence": [ { "database": "UniProtKB", "id": "D4AE85", "url": "https://www.uniprot.org/uniprotkb/D4AE85" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D4AE85-1" }, { "uniprot_canonical_ac": "D4AEE6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4AEE6", "url": "https://www.uniprot.org/uniprotkb/D4AEE6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 401, "chemical_mass": 44964.0, "gene_names": "Ip6k3;Ihpk3;Ip6k3", "protein_name": "Kinase", "disease": [], "molecular_function": [ { "name": "inositol hexakisphosphate kinase activity", "id": "GO:0000828", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000828", "evidence": [ { "database": "UniProtKB", "id": "D4AEE6", "url": "https://www.uniprot.org/uniprotkb/D4AEE6" } ], "pmid": "" }, { "name": "inositol hexakisphosphate 6-kinase activity", "id": "GO:0000831", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000831", "evidence": [ { "database": "UniProtKB", "id": "D4AEE6", "url": "https://www.uniprot.org/uniprotkb/D4AEE6" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "D4AEE6", "url": "https://www.uniprot.org/uniprotkb/D4AEE6" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D4AEE6", "url": "https://www.uniprot.org/uniprotkb/D4AEE6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "D4AEE6", "url": "https://www.uniprot.org/uniprotkb/D4AEE6" } ], "pmid": "" } ], "biological_process": [ { "name": "protein phosphorylation", "id": "GO:0006468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006468", "evidence": [ { "database": "UniProtKB", "id": "D4AEE6", "url": "https://www.uniprot.org/uniprotkb/D4AEE6" } ], "pmid": "" }, { "name": "locomotion", "id": "GO:0040011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040011", "evidence": [ { "database": "UniProtKB", "id": "D4AEE6", "url": "https://www.uniprot.org/uniprotkb/D4AEE6" } ], "pmid": "" }, { "name": "phosphatidylinositol metabolic process", "id": "GO:0046488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046488", "evidence": [ { "database": "UniProtKB", "id": "D4AEE6", "url": "https://www.uniprot.org/uniprotkb/D4AEE6" } ], "pmid": "" }, { "name": "phosphatidylinositol phosphate biosynthetic process", "id": "GO:0046854", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046854", "evidence": [ { "database": "UniProtKB", "id": "D4AEE6", "url": "https://www.uniprot.org/uniprotkb/D4AEE6" } ], "pmid": "" }, { "name": "inositol phosphate biosynthetic process", "id": "GO:0032958", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032958", "evidence": [ { "database": "UniProtKB", "id": "D4AEE6", "url": "https://www.uniprot.org/uniprotkb/D4AEE6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D4AEE6-1" }, { "uniprot_canonical_ac": "D4AEG3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4AEG3", "url": "https://www.uniprot.org/uniprotkb/D4AEG3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 492, "chemical_mass": 57260.0, "gene_names": "Ppil4;Ppil4", "protein_name": "Peptidyl-prolyl cis-trans isomerase", "disease": [], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "D4AEG3", "url": "https://www.uniprot.org/uniprotkb/D4AEG3" } ], "pmid": "" }, { "name": "peptidyl-prolyl cis-trans isomerase activity", "id": "GO:0003755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003755", "evidence": [ { "database": "UniProtKB", "id": "D4AEG3", "url": "https://www.uniprot.org/uniprotkb/D4AEG3" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D4AEG3", "url": "https://www.uniprot.org/uniprotkb/D4AEG3" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "D4AEG3", "url": "https://www.uniprot.org/uniprotkb/D4AEG3" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "D4AEG3", "url": "https://www.uniprot.org/uniprotkb/D4AEG3" } ], "pmid": "" }, { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "D4AEG3", "url": "https://www.uniprot.org/uniprotkb/D4AEG3" } ], "pmid": "" }, { "name": "U2-type catalytic step 1 spliceosome", "id": "GO:0071006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071006", "evidence": [ { "database": "UniProtKB", "id": "D4AEG3", "url": "https://www.uniprot.org/uniprotkb/D4AEG3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D4AEG3-1" }, { "uniprot_canonical_ac": "D4AEJ0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4AEJ0", "url": "https://www.uniprot.org/uniprotkb/D4AEJ0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 384, "chemical_mass": 44273.0, "gene_names": "Nap1l6;Nap1l6;RGD1560617", "protein_name": "", "disease": [], "molecular_function": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "D4AEJ0", "url": "https://www.uniprot.org/uniprotkb/D4AEJ0" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "D4AEJ0", "url": "https://www.uniprot.org/uniprotkb/D4AEJ0" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D4AEJ0", "url": "https://www.uniprot.org/uniprotkb/D4AEJ0" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "D4AEJ0", "url": "https://www.uniprot.org/uniprotkb/D4AEJ0" } ], "pmid": "" } ], "biological_process": [ { "name": "nucleosome assembly", "id": "GO:0006334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006334", "evidence": [ { "database": "UniProtKB", "id": "D4AEJ0", "url": "https://www.uniprot.org/uniprotkb/D4AEJ0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D4AEJ0-1" }, { "uniprot_canonical_ac": "D4AEL4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4AEL4", "url": "https://www.uniprot.org/uniprotkb/D4AEL4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1255, "chemical_mass": 137416.0, "gene_names": "Abcb5;Abcb5", "protein_name": "ATP-binding cassette sub-family B member 5", "disease": [ { "disease_id": "DOID:1485", "name": "cystic fibrosis", "description": "A syndrome that is characterized by the buildup of thick, sticky mucus that can damage many organs.", "url": "https://disease-ontology.org/term/DOID:1485", "evidence": [ { "id": "1485", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1485" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "D4AEL4", "url": "https://www.uniprot.org/uniprotkb/D4AEL4" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "D4AEL4", "url": "https://www.uniprot.org/uniprotkb/D4AEL4" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "D4AEL4", "url": "https://www.uniprot.org/uniprotkb/D4AEL4" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "D4AEL4", "url": "https://www.uniprot.org/uniprotkb/D4AEL4" } ], "pmid": "" } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "D4AEL4", "url": "https://www.uniprot.org/uniprotkb/D4AEL4" } ], "pmid": "" }, { "name": "ATPase-coupled transmembrane transporter activity", "id": "GO:0042626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042626", "evidence": [ { "database": "UniProtKB", "id": "D4AEL4", "url": "https://www.uniprot.org/uniprotkb/D4AEL4" } ], "pmid": "" }, { "name": "ABC-type xenobiotic transporter activity", "id": "GO:0008559", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008559", "evidence": [ { "database": "UniProtKB", "id": "D4AEL4", "url": "https://www.uniprot.org/uniprotkb/D4AEL4" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "D4AEL4", "url": "https://www.uniprot.org/uniprotkb/D4AEL4" } ], "pmid": "" }, { "name": "efflux transmembrane transporter activity", "id": "GO:0015562", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015562", "evidence": [ { "database": "UniProtKB", "id": "D4AEL4", "url": "https://www.uniprot.org/uniprotkb/D4AEL4" } ], "pmid": "" }, { "name": "ABC-type transporter activity", "id": "GO:0140359", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140359", "evidence": [ { "database": "UniProtKB", "id": "D4AEL4", "url": "https://www.uniprot.org/uniprotkb/D4AEL4" } ], "pmid": "" } ], "biological_process": [ { "name": "lipid transport", "id": "GO:0006869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006869", "evidence": [ { "database": "UniProtKB", "id": "D4AEL4", "url": "https://www.uniprot.org/uniprotkb/D4AEL4" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "D4AEL4", "url": "https://www.uniprot.org/uniprotkb/D4AEL4" } ], "pmid": "" }, { "name": "regulation of membrane potential", "id": "GO:0042391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042391", "evidence": [ { "database": "UniProtKB", "id": "D4AEL4", "url": "https://www.uniprot.org/uniprotkb/D4AEL4" } ], "pmid": "" }, { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "D4AEL4", "url": "https://www.uniprot.org/uniprotkb/D4AEL4" } ], "pmid": "" }, { "name": "response to xenobiotic stimulus", "id": "GO:0009410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009410", "evidence": [ { "database": "UniProtKB", "id": "D4AEL4", "url": "https://www.uniprot.org/uniprotkb/D4AEL4" } ], "pmid": "" }, { "name": "eye development", "id": "GO:0001654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001654", "evidence": [ { "database": "UniProtKB", "id": "D4AEL4", "url": "https://www.uniprot.org/uniprotkb/D4AEL4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "D4AEL4-1" }, { "uniprot_canonical_ac": "E9PSN4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "E9PSN4", "url": "https://www.uniprot.org/uniprotkb/E9PSN4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1728, "chemical_mass": 203525.0, "gene_names": "Zc3h13;RGD1307729;Zc3h13", "protein_name": "", "disease": [], "cellular_component": [ { "name": "RNA N6-methyladenosine methyltransferase complex", "id": "GO:0036396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036396", "evidence": [ { "database": "UniProtKB", "id": "E9PSN4", "url": "https://www.uniprot.org/uniprotkb/E9PSN4" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E9PSN4", "url": "https://www.uniprot.org/uniprotkb/E9PSN4" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "E9PSN4", "url": "https://www.uniprot.org/uniprotkb/E9PSN4" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "E9PSN4", "url": "https://www.uniprot.org/uniprotkb/E9PSN4" } ], "pmid": "" }, { "name": "regulation of stem cell population maintenance", "id": "GO:2000036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000036", "evidence": [ { "database": "UniProtKB", "id": "E9PSN4", "url": "https://www.uniprot.org/uniprotkb/E9PSN4" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E9PSN4", "url": "https://www.uniprot.org/uniprotkb/E9PSN4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "E9PSN4-1", "start_pos": "1163", "end_pos": "1163", "site_lbl": "Thr1163", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1163, "start_aa": "Thr", "end_pos": 1163, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1163", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "E9PSN4-1", "start_pos": "1167", "end_pos": "1167", "site_lbl": "Thr1167", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1167, "start_aa": "Thr", "end_pos": 1167, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1167", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "E9PSN4-1" }, { "uniprot_canonical_ac": "E9PSX4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "E9PSX4", "url": "https://www.uniprot.org/uniprotkb/E9PSX4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 386, "chemical_mass": 42007.0, "gene_names": "Il3ra;Cyrl;Il3ra", "protein_name": "Interleukin-3 receptor subunit alpha", "disease": [], "molecular_function": [ { "name": "interleukin-3 receptor activity", "id": "GO:0004912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004912", "evidence": [ { "database": "UniProtKB", "id": "E9PSX4", "url": "https://www.uniprot.org/uniprotkb/E9PSX4" } ], "pmid": "" }, { "name": "cytokine binding", "id": "GO:0019955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019955", "evidence": [ { "database": "UniProtKB", "id": "E9PSX4", "url": "https://www.uniprot.org/uniprotkb/E9PSX4" } ], "pmid": "" }, { "name": "cytokine receptor activity", "id": "GO:0004896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004896", "evidence": [ { "database": "UniProtKB", "id": "E9PSX4", "url": "https://www.uniprot.org/uniprotkb/E9PSX4" } ], "pmid": "" }, { "name": "interleukin-3 binding", "id": "GO:0019978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019978", "evidence": [ { "database": "UniProtKB", "id": "E9PSX4", "url": "https://www.uniprot.org/uniprotkb/E9PSX4" } ], "pmid": "" } ], "biological_process": [ { "name": "interleukin-3-mediated signaling pathway", "id": "GO:0038156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038156", "evidence": [ { "database": "UniProtKB", "id": "E9PSX4", "url": "https://www.uniprot.org/uniprotkb/E9PSX4" } ], "pmid": "" }, { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "E9PSX4", "url": "https://www.uniprot.org/uniprotkb/E9PSX4" } ], "pmid": "" }, { "name": "regulation of cell growth", "id": "GO:0001558", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001558", "evidence": [ { "database": "UniProtKB", "id": "E9PSX4", "url": "https://www.uniprot.org/uniprotkb/E9PSX4" } ], "pmid": "" }, { "name": "cytokine-mediated signaling pathway", "id": "GO:0019221", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019221", "evidence": [ { "database": "UniProtKB", "id": "E9PSX4", "url": "https://www.uniprot.org/uniprotkb/E9PSX4" } ], "pmid": "" }, { "name": "monocyte differentiation", "id": "GO:0030224", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030224", "evidence": [ { "database": "UniProtKB", "id": "E9PSX4", "url": "https://www.uniprot.org/uniprotkb/E9PSX4" } ], "pmid": "" } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E9PSX4", "url": "https://www.uniprot.org/uniprotkb/E9PSX4" } ], "pmid": "" }, { "name": "receptor complex", "id": "GO:0043235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043235", "evidence": [ { "database": "UniProtKB", "id": "E9PSX4", "url": "https://www.uniprot.org/uniprotkb/E9PSX4" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "E9PSX4", "url": "https://www.uniprot.org/uniprotkb/E9PSX4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "E9PSX4-1", "start_pos": "316", "end_pos": "316", "site_lbl": "Thr316", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 316, "start_aa": "Thr", "end_pos": 316, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr316", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "E9PSX4-1", "start_pos": "54", "end_pos": "54", "site_lbl": "Thr54", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 54, "start_aa": "Thr", "end_pos": 54, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr54", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "E9PSX4-1" }, { "uniprot_canonical_ac": "E9PSX7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "E9PSX7", "url": "https://www.uniprot.org/uniprotkb/E9PSX7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 548, "chemical_mass": 60207.0, "gene_names": "Hirip3;Hirip3", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E9PSX7", "url": "https://www.uniprot.org/uniprotkb/E9PSX7" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E9PSX7", "url": "https://www.uniprot.org/uniprotkb/E9PSX7" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "E9PSX7", "url": "https://www.uniprot.org/uniprotkb/E9PSX7" } ], "pmid": "" } ], "biological_process": [ { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "E9PSX7", "url": "https://www.uniprot.org/uniprotkb/E9PSX7" } ], "pmid": "" } ], "molecular_function": [ { "name": "H2A-H2B histone complex chaperone activity", "id": "GO:0000511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000511", "evidence": [ { "database": "UniProtKB", "id": "E9PSX7", "url": "https://www.uniprot.org/uniprotkb/E9PSX7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "E9PSX7-1", "start_pos": "103", "end_pos": "103", "site_lbl": "Thr103", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 103, "start_aa": "Thr", "end_pos": 103, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr103", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "E9PSX7-1" }, { "uniprot_canonical_ac": "E9PT11-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "E9PT11", "url": "https://www.uniprot.org/uniprotkb/E9PT11" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 414, "chemical_mass": 44465.0, "gene_names": "Cbx6;Cbx6", "protein_name": "", "disease": [ { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 }, { "disease_id": "DOID:3068", "name": "glioblastoma", "description": "A malignant astrocytoma characterized by the presence of small areas of necrotizing tissue that is surrounded by anaplastic cells as well as the presence of hyperplastic blood vessels, and that has_material_basis_in abnormally proliferating cells derives_from multiple cell types including astrocytes and oligondroctyes.", "url": "https://disease-ontology.org/term/DOID:3068", "evidence": [ { "id": "3068", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3068" } ], "weight": 0.0 } ], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "E9PT11", "url": "https://www.uniprot.org/uniprotkb/E9PT11" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "E9PT11", "url": "https://www.uniprot.org/uniprotkb/E9PT11" } ], "pmid": "" } ], "molecular_function": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "E9PT11", "url": "https://www.uniprot.org/uniprotkb/E9PT11" } ], "pmid": "" }, { "name": "single-stranded RNA binding", "id": "GO:0003727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003727", "evidence": [ { "database": "UniProtKB", "id": "E9PT11", "url": "https://www.uniprot.org/uniprotkb/E9PT11" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E9PT11", "url": "https://www.uniprot.org/uniprotkb/E9PT11" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E9PT11", "url": "https://www.uniprot.org/uniprotkb/E9PT11" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "E9PT11", "url": "https://www.uniprot.org/uniprotkb/E9PT11" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "E9PT11", "url": "https://www.uniprot.org/uniprotkb/E9PT11" } ], "pmid": "" }, { "name": "heterochromatin", "id": "GO:0000792", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000792", "evidence": [ { "database": "UniProtKB", "id": "E9PT11", "url": "https://www.uniprot.org/uniprotkb/E9PT11" } ], "pmid": "" }, { "name": "PcG protein complex", "id": "GO:0031519", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031519", "evidence": [ { "database": "UniProtKB", "id": "E9PT11", "url": "https://www.uniprot.org/uniprotkb/E9PT11" } ], "pmid": "" }, { "name": "PRC1 complex", "id": "GO:0035102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035102", "evidence": [ { "database": "UniProtKB", "id": "E9PT11", "url": "https://www.uniprot.org/uniprotkb/E9PT11" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "E9PT11-1", "start_pos": "410", "end_pos": "410", "site_lbl": "Thr410", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 410, "start_aa": "Thr", "end_pos": 410, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr410", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "E9PT11-1" }, { "uniprot_canonical_ac": "E9PT20-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1143, "chemical_mass": 124636.0, "gene_names": "Abl1;Abl1;Abl", "protein_name": "Tyrosine-protein kinase", "disease": [ { "disease_id": "DOID:0050866", "name": "oral squamous cell carcinoma", "description": "An oral cavity cancer that has_material_basis_in squamous cells.", "url": "https://disease-ontology.org/term/DOID:0050866", "evidence": [ { "id": "0050866", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050866" } ], "weight": 0.0 }, { "disease_id": "DOID:0080630", "name": "B-lymphoblastic leukemia/lymphoma", "description": "A B-cell acute lymphoblastic leukemia that is characterized by the presence of too many B-cell lymphoblasts in the blood and bone marrow.", "url": "https://disease-ontology.org/term/DOID:0080630", "evidence": [ { "id": "0080630", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080630" } ], "weight": 0.0 }, { "disease_id": "DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ], "weight": 0.0 }, { "disease_id": "DOID:14330", "name": "Parkinson's disease", "description": "A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.", "url": "https://disease-ontology.org/term/DOID:14330", "evidence": [ { "id": "14330", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14330" } ], "weight": 0.0 }, { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 }, { "disease_id": "DOID:4914", "name": "esophagus adenocarcinoma", "description": "An esophageal carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:4914", "evidence": [ { "id": "4914", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4914" } ], "weight": 0.0 }, { "disease_id": "DOID:5199", "name": "ureteral obstruction", "description": "An urinary tract obstruction that is characterized by a blockage in one or both of the tubes (ureters) that carry urine from the kidneys to the bladder.", "url": "https://disease-ontology.org/term/DOID:5199", "evidence": [ { "id": "5199", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5199" } ], "weight": 0.0 }, { "disease_id": "DOID:8552", "name": "chronic myeloid leukemia", "description": "A myeloid leukemia that is characterized by over production of white blood cells.", "url": "https://disease-ontology.org/term/DOID:8552", "evidence": [ { "id": "8552", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8552" } ], "weight": 0.0 }, { "disease_id": "DOID:9119", "name": "acute myeloid leukemia", "description": "A myeloid leukemia that is characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal blood cells.", "url": "https://disease-ontology.org/term/DOID:9119", "evidence": [ { "id": "9119", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9119" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 } ], "biological_process": [ { "name": "positive regulation of extracellular matrix organization", "id": "GO:1903055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903055", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "DNA conformation change", "id": "GO:0071103", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071103", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "circulatory system development", "id": "GO:0072359", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072359", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "positive regulation of establishment of T cell polarity", "id": "GO:1903905", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903905", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "negative regulation of double-strand break repair via homologous recombination", "id": "GO:2000042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000042", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "protein phosphorylation", "id": "GO:0006468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006468", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "response to oxidative stress", "id": "GO:0006979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006979", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "positive regulation of cytosolic calcium ion concentration", "id": "GO:0007204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007204", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "integrin-mediated signaling pathway", "id": "GO:0007229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007229", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "learning or memory", "id": "GO:0007611", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007611", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "associative learning", "id": "GO:0008306", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008306", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "peptidyl-tyrosine phosphorylation", "id": "GO:0018108", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018108", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "regulation of actin cytoskeleton organization", "id": "GO:0032956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032956", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "regulation of cell population proliferation", "id": "GO:0042127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042127", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "positive regulation of apoptotic process", "id": "GO:0043065", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043065", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "positive regulation of mitotic cell cycle", "id": "GO:0045931", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045931", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "ephrin receptor signaling pathway", "id": "GO:0048013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048013", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "neuromuscular process controlling balance", "id": "GO:0050885", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050885", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "positive regulation of ERK1 and ERK2 cascade", "id": "GO:0070374", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070374", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "negative regulation of long-term synaptic potentiation", "id": "GO:1900272", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900272", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "positive regulation of T cell migration", "id": "GO:2000406", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000406", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "phagocytosis", "id": "GO:0006909", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006909", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "positive regulation of endothelial cell migration", "id": "GO:0010595", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010595", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "T cell receptor signaling pathway", "id": "GO:0050852", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050852", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "cellular response to lipopolysaccharide", "id": "GO:0071222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071222", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "positive regulation of canonical NF-kappaB signal transduction", "id": "GO:0043123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043123", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "positive regulation of vasoconstriction", "id": "GO:0045907", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045907", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "protein autophosphorylation", "id": "GO:0046777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046777", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "positive regulation of stress fiber assembly", "id": "GO:0051496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051496", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "neural tube closure", "id": "GO:0001843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001843", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "B-1 B cell homeostasis", "id": "GO:0001922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001922", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "B cell proliferation involved in immune response", "id": "GO:0002322", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002322", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "transitional one stage B cell differentiation", "id": "GO:0002333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002333", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "autophagy", "id": "GO:0006914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006914", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "epidermal growth factor receptor signaling pathway", "id": "GO:0007173", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007173", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "post-embryonic development", "id": "GO:0009791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009791", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "cerebellum morphogenesis", "id": "GO:0021587", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021587", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "negative regulation of cell-cell adhesion", "id": "GO:0022408", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022408", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "microspike assembly", "id": "GO:0030035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030035", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "neuron differentiation", "id": "GO:0030182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030182", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "negative regulation of BMP signaling pathway", "id": "GO:0030514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030514", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "regulation of axon extension", "id": "GO:0030516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030516", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "regulation of microtubule polymerization", "id": "GO:0031113", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031113", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "regulation of Cdc42 protein signal transduction", "id": "GO:0032489", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032489", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "positive regulation of osteoblast proliferation", "id": "GO:0033690", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033690", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "substrate adhesion-dependent cell spreading", "id": "GO:0034446", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034446", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "cellular response to oxidative stress", "id": "GO:0034599", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034599", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "platelet-derived growth factor receptor-beta signaling pathway", "id": "GO:0035791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035791", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "neuropilin signaling pathway", "id": "GO:0038189", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038189", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "signal transduction in response to DNA damage", "id": "GO:0042770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042770", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "endothelial cell migration", "id": "GO:0043542", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043542", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "regulation of T cell differentiation", "id": "GO:0045580", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045580", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "negative regulation of mitotic cell cycle", "id": "GO:0045930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045930", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "alpha-beta T cell differentiation", "id": "GO:0046632", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046632", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "spleen development", "id": "GO:0048536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048536", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "thymus development", "id": "GO:0048538", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048538", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "activated T cell proliferation", "id": "GO:0050798", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050798", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "B cell receptor signaling pathway", "id": "GO:0050853", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050853", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "positive regulation of release of sequestered calcium ion into cytosol", "id": "GO:0051281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051281", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "negative regulation of ubiquitin-protein transferase activity", "id": "GO:0051444", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051444", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "positive regulation of focal adhesion assembly", "id": "GO:0051894", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051894", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "Bergmann glial cell differentiation", "id": "GO:0060020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060020", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "neuroepithelial cell differentiation", "id": "GO:0060563", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060563", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "cellular response to hydrogen peroxide", "id": "GO:0070301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070301", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "negative regulation of ERK1 and ERK2 cascade", "id": "GO:0070373", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070373", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "positive regulation of cell migration involved in sprouting angiogenesis", "id": "GO:0090050", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090050", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "positive regulation of substrate adhesion-dependent cell spreading", "id": "GO:1900026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900026", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "regulation of extracellular matrix organization", "id": "GO:1903053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903053", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "regulation of modification of synaptic structure", "id": "GO:1905244", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905244", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "positive regulation of blood vessel branching", "id": "GO:1905555", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905555", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "positive regulation of Wnt signaling pathway, planar cell polarity pathway", "id": "GO:2000096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000096", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "negative regulation of endothelial cell apoptotic process", "id": "GO:2000352", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000352", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "negative regulation of cellular senescence", "id": "GO:2000773", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000773", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "positive regulation of type II interferon production", "id": "GO:0032729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032729", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "cellular response to transforming growth factor beta stimulus", "id": "GO:0071560", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071560", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "actin filament polymerization", "id": "GO:0030041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030041", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "positive regulation of neuron apoptotic process", "id": "GO:0043525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043525", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "positive regulation of fibroblast proliferation", "id": "GO:0048146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048146", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "canonical NF-kappaB signal transduction", "id": "GO:0007249", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007249", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "response to xenobiotic stimulus", "id": "GO:0009410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009410", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "positive regulation of interleukin-2 production", "id": "GO:0032743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032743", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "response to endoplasmic reticulum stress", "id": "GO:0034976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034976", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "platelet-derived growth factor receptor signaling pathway", "id": "GO:0048008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048008", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "cardiac muscle cell proliferation", "id": "GO:0060038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060038", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "phospholipase C-inhibiting G protein-coupled receptor signaling pathway", "id": "GO:0030845", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030845", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "response to epinephrine", "id": "GO:0071871", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071871", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "myoblast proliferation", "id": "GO:0051450", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051450", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "B cell proliferation", "id": "GO:0042100", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042100", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "positive regulation of dendrite development", "id": "GO:1900006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900006", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "regulation of cellular senescence", "id": "GO:2000772", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000772", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "regulation of postsynaptic specialization assembly", "id": "GO:0099150", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099150", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "podocyte apoptotic process", "id": "GO:1903210", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903210", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "DN4 thymocyte differentiation", "id": "GO:1904157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904157", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "protein localization to cytoplasmic microtubule plus-end", "id": "GO:1904518", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904518", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "positive regulation of phospholipase C/protein kinase C signal transduction", "id": "GO:0141214", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141214", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "cell communication", "id": "GO:0007154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007154", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "signaling", "id": "GO:0023052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0023052", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" } ], "cellular_component": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "growth cone", "id": "GO:0030426", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030426", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "cell leading edge", "id": "GO:0031252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031252", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "ruffle", "id": "GO:0001726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001726", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" } ], "molecular_function": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "phosphotyrosine residue binding", "id": "GO:0001784", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001784", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "protein tyrosine kinase activity", "id": "GO:0004713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004713", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "non-membrane spanning protein tyrosine kinase activity", "id": "GO:0004715", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004715", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "enzyme activator activity", "id": "GO:0008047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008047", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "enzyme binding", "id": "GO:0019899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019899", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "protein domain specific binding", "id": "GO:0019904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019904", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "manganese ion binding", "id": "GO:0030145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030145", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "ephrin receptor binding", "id": "GO:0046875", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046875", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "mitogen-activated protein kinase binding", "id": "GO:0051019", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051019", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "protein kinase C binding", "id": "GO:0005080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005080", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "proline-rich region binding", "id": "GO:0070064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070064", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "syntaxin binding", "id": "GO:0019905", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019905", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "neuropilin binding", "id": "GO:0038191", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038191", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "SH2 domain binding", "id": "GO:0042169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042169", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activator activity", "id": "GO:0043539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043539", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "kinase activity", "id": "GO:0016301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016301", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "four-way junction DNA binding", "id": "GO:0000400", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000400", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "bubble DNA binding", "id": "GO:0000405", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000405", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "delta-catenin binding", "id": "GO:0070097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070097", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" }, { "name": "sequence-specific double-stranded DNA binding", "id": "GO:1990837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990837", "evidence": [ { "database": "UniProtKB", "id": "E9PT20", "url": "https://www.uniprot.org/uniprotkb/E9PT20" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "E9PT20-1", "start_pos": "632", "end_pos": "632", "site_lbl": "Thr632", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 632, "start_aa": "Thr", "end_pos": 632, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr632", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "E9PT20-1", "start_pos": "994", "end_pos": "994", "site_lbl": "Thr994", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 994, "start_aa": "Thr", "end_pos": 994, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr994", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "E9PT20-1" }, { "uniprot_canonical_ac": "E9PT90-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "E9PT90", "url": "https://www.uniprot.org/uniprotkb/E9PT90" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 682, "chemical_mass": 74122.0, "gene_names": "Spart;Spart;Spg20", "protein_name": "Spartin", "disease": [ { "disease_id": "DOID:0050886", "name": "Troyer syndrome", "description": "A hereditary spastic paraplegia that is characterized by spasticity of the leg muscles, progressive muscle weakness, paraplegia, muscle wasting in the hands and feet (distal amyotrophy), small stature, developmental delay, learning disorders, speech difficulties (dysarthria), and mood swings, and has_material_basis_in a mutation of the SPG20 gene.", "url": "https://disease-ontology.org/term/DOID:0050886", "evidence": [ { "id": "0050886", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050886" } ], "weight": 0.0 } ], "biological_process": [ { "name": "negative regulation of collateral sprouting in absence of injury", "id": "GO:0048698", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048698", "evidence": [ { "database": "UniProtKB", "id": "E9PT90", "url": "https://www.uniprot.org/uniprotkb/E9PT90" } ], "pmid": "" }, { "name": "lipid transport", "id": "GO:0006869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006869", "evidence": [ { "database": "UniProtKB", "id": "E9PT90", "url": "https://www.uniprot.org/uniprotkb/E9PT90" } ], "pmid": "" }, { "name": "neuromuscular process", "id": "GO:0050905", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050905", "evidence": [ { "database": "UniProtKB", "id": "E9PT90", "url": "https://www.uniprot.org/uniprotkb/E9PT90" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "E9PT90", "url": "https://www.uniprot.org/uniprotkb/E9PT90" } ], "pmid": "" }, { "name": "adipose tissue development", "id": "GO:0060612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060612", "evidence": [ { "database": "UniProtKB", "id": "E9PT90", "url": "https://www.uniprot.org/uniprotkb/E9PT90" } ], "pmid": "" }, { "name": "regulation of mitochondrial membrane potential", "id": "GO:0051881", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051881", "evidence": [ { "database": "UniProtKB", "id": "E9PT90", "url": "https://www.uniprot.org/uniprotkb/E9PT90" } ], "pmid": "" }, { "name": "negative regulation of BMP signaling pathway", "id": "GO:0030514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030514", "evidence": [ { "database": "UniProtKB", "id": "E9PT90", "url": "https://www.uniprot.org/uniprotkb/E9PT90" } ], "pmid": "" }, { "name": "lipid droplet organization", "id": "GO:0034389", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034389", "evidence": [ { "database": "UniProtKB", "id": "E9PT90", "url": "https://www.uniprot.org/uniprotkb/E9PT90" } ], "pmid": "" }, { "name": "lipophagy", "id": "GO:0061724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061724", "evidence": [ { "database": "UniProtKB", "id": "E9PT90", "url": "https://www.uniprot.org/uniprotkb/E9PT90" } ], "pmid": "" }, { "name": "midbody abscission", "id": "GO:0061952", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061952", "evidence": [ { "database": "UniProtKB", "id": "E9PT90", "url": "https://www.uniprot.org/uniprotkb/E9PT90" } ], "pmid": "" }, { "name": "lipid catabolic process", "id": "GO:0016042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016042", "evidence": [ { "database": "UniProtKB", "id": "E9PT90", "url": "https://www.uniprot.org/uniprotkb/E9PT90" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E9PT90", "url": "https://www.uniprot.org/uniprotkb/E9PT90" } ], "pmid": "" }, { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "E9PT90", "url": "https://www.uniprot.org/uniprotkb/E9PT90" } ], "pmid": "" }, { "name": "lipid droplet", "id": "GO:0005811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005811", "evidence": [ { "database": "UniProtKB", "id": "E9PT90", "url": "https://www.uniprot.org/uniprotkb/E9PT90" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E9PT90", "url": "https://www.uniprot.org/uniprotkb/E9PT90" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E9PT90", "url": "https://www.uniprot.org/uniprotkb/E9PT90" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "E9PT90", "url": "https://www.uniprot.org/uniprotkb/E9PT90" } ], "pmid": "" }, { "name": "midbody", "id": "GO:0030496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030496", "evidence": [ { "database": "UniProtKB", "id": "E9PT90", "url": "https://www.uniprot.org/uniprotkb/E9PT90" } ], "pmid": "" } ], "molecular_function": [ { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "E9PT90", "url": "https://www.uniprot.org/uniprotkb/E9PT90" } ], "pmid": "" }, { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "E9PT90", "url": "https://www.uniprot.org/uniprotkb/E9PT90" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "E9PT90-1", "start_pos": "489", "end_pos": "489", "site_lbl": "Thr489", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 489, "start_aa": "Thr", "end_pos": 489, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr489", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "E9PT90-1" }, { "uniprot_canonical_ac": "E9PTK4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "E9PTK4", "url": "https://www.uniprot.org/uniprotkb/E9PTK4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 745, "chemical_mass": 82710.0, "gene_names": "Thnsl1;Thnsl1", "protein_name": "", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E9PTK4", "url": "https://www.uniprot.org/uniprotkb/E9PTK4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "E9PTK4-1" }, { "uniprot_canonical_ac": "E9PTL1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "E9PTL1", "url": "https://www.uniprot.org/uniprotkb/E9PTL1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 686, "chemical_mass": 77312.0, "gene_names": "Rad17;Rad17", "protein_name": "Cell cycle checkpoint protein RAD17", "disease": [], "biological_process": [ { "name": "protein localization to site of double-strand break", "id": "GO:1990166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990166", "evidence": [ { "database": "UniProtKB", "id": "E9PTL1", "url": "https://www.uniprot.org/uniprotkb/E9PTL1" } ], "pmid": "" }, { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "E9PTL1", "url": "https://www.uniprot.org/uniprotkb/E9PTL1" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "E9PTL1", "url": "https://www.uniprot.org/uniprotkb/E9PTL1" } ], "pmid": "" }, { "name": "mitotic intra-S DNA damage checkpoint signaling", "id": "GO:0031573", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031573", "evidence": [ { "database": "UniProtKB", "id": "E9PTL1", "url": "https://www.uniprot.org/uniprotkb/E9PTL1" } ], "pmid": "" }, { "name": "regulation of phosphorylation", "id": "GO:0042325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042325", "evidence": [ { "database": "UniProtKB", "id": "E9PTL1", "url": "https://www.uniprot.org/uniprotkb/E9PTL1" } ], "pmid": "" }, { "name": "negative regulation of DNA replication", "id": "GO:0008156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008156", "evidence": [ { "database": "UniProtKB", "id": "E9PTL1", "url": "https://www.uniprot.org/uniprotkb/E9PTL1" } ], "pmid": "" }, { "name": "mitotic DNA replication checkpoint signaling", "id": "GO:0033314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033314", "evidence": [ { "database": "UniProtKB", "id": "E9PTL1", "url": "https://www.uniprot.org/uniprotkb/E9PTL1" } ], "pmid": "" }, { "name": "DNA damage checkpoint signaling", "id": "GO:0000077", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000077", "evidence": [ { "database": "UniProtKB", "id": "E9PTL1", "url": "https://www.uniprot.org/uniprotkb/E9PTL1" } ], "pmid": "" } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "E9PTL1", "url": "https://www.uniprot.org/uniprotkb/E9PTL1" } ], "pmid": "" }, { "name": "DNA clamp loader activity", "id": "GO:0003689", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003689", "evidence": [ { "database": "UniProtKB", "id": "E9PTL1", "url": "https://www.uniprot.org/uniprotkb/E9PTL1" } ], "pmid": "" }, { "name": "chromatin-protein adaptor activity", "id": "GO:0140463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140463", "evidence": [ { "database": "UniProtKB", "id": "E9PTL1", "url": "https://www.uniprot.org/uniprotkb/E9PTL1" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E9PTL1", "url": "https://www.uniprot.org/uniprotkb/E9PTL1" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E9PTL1", "url": "https://www.uniprot.org/uniprotkb/E9PTL1" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "E9PTL1", "url": "https://www.uniprot.org/uniprotkb/E9PTL1" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "E9PTL1", "url": "https://www.uniprot.org/uniprotkb/E9PTL1" } ], "pmid": "" }, { "name": "site of double-strand break", "id": "GO:0035861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035861", "evidence": [ { "database": "UniProtKB", "id": "E9PTL1", "url": "https://www.uniprot.org/uniprotkb/E9PTL1" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "E9PTL1", "url": "https://www.uniprot.org/uniprotkb/E9PTL1" } ], "pmid": "" }, { "name": "Rad17 RFC-like complex", "id": "GO:0031389", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031389", "evidence": [ { "database": "UniProtKB", "id": "E9PTL1", "url": "https://www.uniprot.org/uniprotkb/E9PTL1" } ], "pmid": "" }, { "name": "chromosome, telomeric repeat region", "id": "GO:0140445", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140445", "evidence": [ { "database": "UniProtKB", "id": "E9PTL1", "url": "https://www.uniprot.org/uniprotkb/E9PTL1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "E9PTL1-1" }, { "uniprot_canonical_ac": "E9PTR3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "E9PTR3", "url": "https://www.uniprot.org/uniprotkb/E9PTR3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1373, "chemical_mass": 159040.0, "gene_names": "Drosha;Drosha;Etohi2;RGD1307626;Rn3;Rnasen", "protein_name": "Ribonuclease 3", "disease": [ { "disease_id": "DOID:936", "name": "brain disease", "description": "A central nervous system disease that is located_in the brain.", "url": "https://disease-ontology.org/term/DOID:936", "evidence": [ { "id": "936", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:936" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "E9PTR3", "url": "https://www.uniprot.org/uniprotkb/E9PTR3" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E9PTR3", "url": "https://www.uniprot.org/uniprotkb/E9PTR3" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E9PTR3", "url": "https://www.uniprot.org/uniprotkb/E9PTR3" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "E9PTR3", "url": "https://www.uniprot.org/uniprotkb/E9PTR3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E9PTR3", "url": "https://www.uniprot.org/uniprotkb/E9PTR3" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "E9PTR3", "url": "https://www.uniprot.org/uniprotkb/E9PTR3" } ], "pmid": "" }, { "name": "microprocessor complex", "id": "GO:0070877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070877", "evidence": [ { "database": "UniProtKB", "id": "E9PTR3", "url": "https://www.uniprot.org/uniprotkb/E9PTR3" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "E9PTR3", "url": "https://www.uniprot.org/uniprotkb/E9PTR3" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "E9PTR3", "url": "https://www.uniprot.org/uniprotkb/E9PTR3" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "E9PTR3", "url": "https://www.uniprot.org/uniprotkb/E9PTR3" } ], "pmid": "" }, { "name": "SMAD binding", "id": "GO:0046332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046332", "evidence": [ { "database": "UniProtKB", "id": "E9PTR3", "url": "https://www.uniprot.org/uniprotkb/E9PTR3" } ], "pmid": "" }, { "name": "lipopolysaccharide binding", "id": "GO:0001530", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001530", "evidence": [ { "database": "UniProtKB", "id": "E9PTR3", "url": "https://www.uniprot.org/uniprotkb/E9PTR3" } ], "pmid": "" }, { "name": "RNA endonuclease activity", "id": "GO:0004521", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004521", "evidence": [ { "database": "UniProtKB", "id": "E9PTR3", "url": "https://www.uniprot.org/uniprotkb/E9PTR3" } ], "pmid": "" }, { "name": "DEAD/H-box RNA helicase binding", "id": "GO:0017151", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017151", "evidence": [ { "database": "UniProtKB", "id": "E9PTR3", "url": "https://www.uniprot.org/uniprotkb/E9PTR3" } ], "pmid": "" }, { "name": "R-SMAD binding", "id": "GO:0070412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070412", "evidence": [ { "database": "UniProtKB", "id": "E9PTR3", "url": "https://www.uniprot.org/uniprotkb/E9PTR3" } ], "pmid": "" }, { "name": "ribonuclease III activity", "id": "GO:0004525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004525", "evidence": [ { "database": "UniProtKB", "id": "E9PTR3", "url": "https://www.uniprot.org/uniprotkb/E9PTR3" } ], "pmid": "" }, { "name": "primary miRNA binding", "id": "GO:0070878", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070878", "evidence": [ { "database": "UniProtKB", "id": "E9PTR3", "url": "https://www.uniprot.org/uniprotkb/E9PTR3" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of gene expression", "id": "GO:0010628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010628", "evidence": [ { "database": "UniProtKB", "id": "E9PTR3", "url": "https://www.uniprot.org/uniprotkb/E9PTR3" } ], "pmid": "" }, { "name": "defense response to Gram-negative bacterium", "id": "GO:0050829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050829", "evidence": [ { "database": "UniProtKB", "id": "E9PTR3", "url": "https://www.uniprot.org/uniprotkb/E9PTR3" } ], "pmid": "" }, { "name": "defense response to Gram-positive bacterium", "id": "GO:0050830", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050830", "evidence": [ { "database": "UniProtKB", "id": "E9PTR3", "url": "https://www.uniprot.org/uniprotkb/E9PTR3" } ], "pmid": "" }, { "name": "regulation of inflammatory response", "id": "GO:0050727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050727", "evidence": [ { "database": "UniProtKB", "id": "E9PTR3", "url": "https://www.uniprot.org/uniprotkb/E9PTR3" } ], "pmid": "" }, { "name": "miRNA metabolic process", "id": "GO:0010586", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010586", "evidence": [ { "database": "UniProtKB", "id": "E9PTR3", "url": "https://www.uniprot.org/uniprotkb/E9PTR3" } ], "pmid": "" }, { "name": "pre-miRNA processing", "id": "GO:0031054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031054", "evidence": [ { "database": "UniProtKB", "id": "E9PTR3", "url": "https://www.uniprot.org/uniprotkb/E9PTR3" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "E9PTR3", "url": "https://www.uniprot.org/uniprotkb/E9PTR3" } ], "pmid": "" }, { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "E9PTR3", "url": "https://www.uniprot.org/uniprotkb/E9PTR3" } ], "pmid": "" }, { "name": "regulation of miRNA metabolic process", "id": "GO:2000628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000628", "evidence": [ { "database": "UniProtKB", "id": "E9PTR3", "url": "https://www.uniprot.org/uniprotkb/E9PTR3" } ], "pmid": "" }, { "name": "primary miRNA processing", "id": "GO:0031053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031053", "evidence": [ { "database": "UniProtKB", "id": "E9PTR3", "url": "https://www.uniprot.org/uniprotkb/E9PTR3" } ], "pmid": "" }, { "name": "regulation of regulatory T cell differentiation", "id": "GO:0045589", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045589", "evidence": [ { "database": "UniProtKB", "id": "E9PTR3", "url": "https://www.uniprot.org/uniprotkb/E9PTR3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "E9PTR3-1", "start_pos": "957", "end_pos": "957", "site_lbl": "Thr957", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 957, "start_aa": "Thr", "end_pos": 957, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr957", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "E9PTR3-1" }, { "uniprot_canonical_ac": "E9PTS6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "E9PTS6", "url": "https://www.uniprot.org/uniprotkb/E9PTS6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 501, "chemical_mass": 54027.0, "gene_names": "Klf11;Klf11;Tcfcp2l2", "protein_name": "", "disease": [ { "disease_id": "DOID:0111106", "name": "maturity-onset diabetes of the young type 7", "description": "A maturity-onset diabetes of the young that has_material_basis_in heterozygous mutation in the KLF11 gene on chromosome 2p25.", "url": "https://disease-ontology.org/term/DOID:0111106", "evidence": [ { "id": "0111106", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111106" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 } ], "biological_process": [ { "name": "cellular response to endothelin", "id": "GO:1990859", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990859", "evidence": [ { "database": "UniProtKB", "id": "E9PTS6", "url": "https://www.uniprot.org/uniprotkb/E9PTS6" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "E9PTS6", "url": "https://www.uniprot.org/uniprotkb/E9PTS6" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E9PTS6", "url": "https://www.uniprot.org/uniprotkb/E9PTS6" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "E9PTS6", "url": "https://www.uniprot.org/uniprotkb/E9PTS6" } ], "pmid": "" }, { "name": "negative regulation of cell population proliferation", "id": "GO:0008285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008285", "evidence": [ { "database": "UniProtKB", "id": "E9PTS6", "url": "https://www.uniprot.org/uniprotkb/E9PTS6" } ], "pmid": "" }, { "name": "positive regulation of apoptotic process", "id": "GO:0043065", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043065", "evidence": [ { "database": "UniProtKB", "id": "E9PTS6", "url": "https://www.uniprot.org/uniprotkb/E9PTS6" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "E9PTS6", "url": "https://www.uniprot.org/uniprotkb/E9PTS6" } ], "pmid": "" }, { "name": "regulation of G1/S transition of mitotic cell cycle", "id": "GO:2000045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000045", "evidence": [ { "database": "UniProtKB", "id": "E9PTS6", "url": "https://www.uniprot.org/uniprotkb/E9PTS6" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "E9PTS6", "url": "https://www.uniprot.org/uniprotkb/E9PTS6" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E9PTS6", "url": "https://www.uniprot.org/uniprotkb/E9PTS6" } ], "pmid": "" }, { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "E9PTS6", "url": "https://www.uniprot.org/uniprotkb/E9PTS6" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "E9PTS6", "url": "https://www.uniprot.org/uniprotkb/E9PTS6" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "E9PTS6", "url": "https://www.uniprot.org/uniprotkb/E9PTS6" } ], "pmid": "" }, { "name": "sequence-specific double-stranded DNA binding", "id": "GO:1990837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990837", "evidence": [ { "database": "UniProtKB", "id": "E9PTS6", "url": "https://www.uniprot.org/uniprotkb/E9PTS6" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E9PTS6", "url": "https://www.uniprot.org/uniprotkb/E9PTS6" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E9PTS6", "url": "https://www.uniprot.org/uniprotkb/E9PTS6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "E9PTS6-1", "start_pos": "101", "end_pos": "101", "site_lbl": "Thr101", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 101, "start_aa": "Thr", "end_pos": 101, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr101", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "E9PTS6-1", "start_pos": "136", "end_pos": "136", "site_lbl": "Thr136", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 136, "start_aa": "Thr", "end_pos": 136, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr136", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "E9PTS6-1", "start_pos": "181", "end_pos": "181", "site_lbl": "Thr181", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 181, "start_aa": "Thr", "end_pos": 181, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr181", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "E9PTS6-1" }, { "uniprot_canonical_ac": "E9PTX9-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "E9PTX9", "url": "https://www.uniprot.org/uniprotkb/E9PTX9" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1203, "chemical_mass": 130367.0, "gene_names": "Slc12a2;Bsc2;Nkcc1;Slc12a2", "protein_name": "", "disease": [ { "disease_id": "DOID:0112159", "name": "autosomal dominant nonsyndromic deafness 78", "description": "An autosomal dominant nonsyndromic deafness characterized by congenital onset of profound bilateral sensorineural hearing loss affecting all frequencies that has_material_basis_in heterozygous mutation in the carboxy-terminal domain of the SLC12A2 gene on chromosome 5q23.3.", "url": "https://disease-ontology.org/term/DOID:0112159", "evidence": [ { "id": "0112159", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112159" } ], "weight": 0.0 }, { "disease_id": "DOID:10003", "name": "sensorineural hearing loss", "description": "An inner ear disease that is characterized by hearing loss resulting from damage to the cochlea, auditory nerve and/or brainstem.", "url": "https://disease-ontology.org/term/DOID:10003", "evidence": [ { "id": "10003", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10003" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:1826", "name": "epilepsy", "description": "A brain disease that is characterized by the occurrance of at least two unprovoked seizures resulting from a persistent epileptogenic abnormality of the brain that is able to spontaneously generate paroxysmal activity and typically manifested by sudden brief episodes of altered or diminished consciousness, involuntary movements, or convulsions.", "url": "https://disease-ontology.org/term/DOID:1826", "evidence": [ { "id": "1826", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1826" } ], "weight": 0.0 }, { "disease_id": "DOID:224", "name": "transient cerebral ischemia", "description": "A brain ischemia that is characterized by ischemia of brief duration and without resultant tissue death.", "url": "https://disease-ontology.org/term/DOID:224", "evidence": [ { "id": "224", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:224" } ], "weight": 0.0 }, { "disease_id": "DOID:3525", "name": "middle cerebral artery infarction", "description": "", "url": "https://disease-ontology.org/term/DOID:3525", "evidence": [ { "id": "3525", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3525" } ], "weight": 0.0 } ], "biological_process": [ { "name": "cellular response to chemokine", "id": "GO:1990869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990869", "evidence": [ { "database": "UniProtKB", "id": "E9PTX9", "url": "https://www.uniprot.org/uniprotkb/E9PTX9" } ], "pmid": "" }, { "name": "intracellular chloride ion homeostasis", "id": "GO:0030644", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030644", "evidence": [ { "database": "UniProtKB", "id": "E9PTX9", "url": "https://www.uniprot.org/uniprotkb/E9PTX9" } ], "pmid": "" }, { "name": "negative regulation of vascular wound healing", "id": "GO:0061044", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061044", "evidence": [ { "database": "UniProtKB", "id": "E9PTX9", "url": "https://www.uniprot.org/uniprotkb/E9PTX9" } ], "pmid": "" }, { "name": "transepithelial ammonium transport", "id": "GO:0070634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070634", "evidence": [ { "database": "UniProtKB", "id": "E9PTX9", "url": "https://www.uniprot.org/uniprotkb/E9PTX9" } ], "pmid": "" }, { "name": "detection of mechanical stimulus involved in sensory perception of sound", "id": "GO:0050910", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050910", "evidence": [ { "database": "UniProtKB", "id": "E9PTX9", "url": "https://www.uniprot.org/uniprotkb/E9PTX9" } ], "pmid": "" }, { "name": "gamma-aminobutyric acid signaling pathway", "id": "GO:0007214", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007214", "evidence": [ { "database": "UniProtKB", "id": "E9PTX9", "url": "https://www.uniprot.org/uniprotkb/E9PTX9" } ], "pmid": "" }, { "name": "cell volume homeostasis", "id": "GO:0006884", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006884", "evidence": [ { "database": "UniProtKB", "id": "E9PTX9", "url": "https://www.uniprot.org/uniprotkb/E9PTX9" } ], "pmid": "" }, { "name": "multicellular organism growth", "id": "GO:0035264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035264", "evidence": [ { "database": "UniProtKB", "id": "E9PTX9", "url": "https://www.uniprot.org/uniprotkb/E9PTX9" } ], "pmid": "" }, { "name": "cellular response to lipopolysaccharide", "id": "GO:0071222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071222", "evidence": [ { "database": "UniProtKB", "id": "E9PTX9", "url": "https://www.uniprot.org/uniprotkb/E9PTX9" } ], "pmid": "" }, { "name": "intracellular sodium ion homeostasis", "id": "GO:0006883", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006883", "evidence": [ { "database": "UniProtKB", "id": "E9PTX9", "url": "https://www.uniprot.org/uniprotkb/E9PTX9" } ], "pmid": "" }, { "name": "potassium ion transport", "id": "GO:0006813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006813", "evidence": [ { "database": "UniProtKB", "id": "E9PTX9", "url": "https://www.uniprot.org/uniprotkb/E9PTX9" } ], "pmid": "" }, { "name": "chloride transport", "id": "GO:0006821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006821", "evidence": [ { "database": "UniProtKB", "id": "E9PTX9", "url": "https://www.uniprot.org/uniprotkb/E9PTX9" } ], "pmid": "" }, { "name": "chloride transmembrane transport", "id": "GO:1902476", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902476", "evidence": [ { "database": "UniProtKB", "id": "E9PTX9", "url": "https://www.uniprot.org/uniprotkb/E9PTX9" } ], "pmid": "" }, { "name": "sodium ion transmembrane transport", "id": "GO:0035725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035725", "evidence": [ { "database": "UniProtKB", "id": "E9PTX9", "url": "https://www.uniprot.org/uniprotkb/E9PTX9" } ], "pmid": "" }, { "name": "sodium ion transport", "id": "GO:0006814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006814", "evidence": [ { "database": "UniProtKB", "id": "E9PTX9", "url": "https://www.uniprot.org/uniprotkb/E9PTX9" } ], "pmid": "" }, { "name": "potassium ion homeostasis", "id": "GO:0055075", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055075", "evidence": [ { "database": "UniProtKB", "id": "E9PTX9", "url": "https://www.uniprot.org/uniprotkb/E9PTX9" } ], "pmid": "" }, { "name": "sodium ion homeostasis", "id": "GO:0055078", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055078", "evidence": [ { "database": "UniProtKB", "id": "E9PTX9", "url": "https://www.uniprot.org/uniprotkb/E9PTX9" } ], "pmid": "" }, { "name": "intracellular potassium ion homeostasis", "id": "GO:0030007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030007", "evidence": [ { "database": "UniProtKB", "id": "E9PTX9", "url": "https://www.uniprot.org/uniprotkb/E9PTX9" } ], "pmid": "" }, { "name": "potassium ion import across plasma membrane", "id": "GO:1990573", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990573", "evidence": [ { "database": "UniProtKB", "id": "E9PTX9", "url": "https://www.uniprot.org/uniprotkb/E9PTX9" } ], "pmid": "" }, { "name": "chloride ion homeostasis", "id": "GO:0055064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055064", "evidence": [ { "database": "UniProtKB", "id": "E9PTX9", "url": "https://www.uniprot.org/uniprotkb/E9PTX9" } ], "pmid": "" }, { "name": "ammonium transmembrane transport", "id": "GO:0072488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072488", "evidence": [ { "database": "UniProtKB", "id": "E9PTX9", "url": "https://www.uniprot.org/uniprotkb/E9PTX9" } ], "pmid": "" }, { "name": "positive regulation of cell volume", "id": "GO:0045795", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045795", "evidence": [ { "database": "UniProtKB", "id": "E9PTX9", "url": "https://www.uniprot.org/uniprotkb/E9PTX9" } ], "pmid": "" }, { "name": "transepithelial chloride transport", "id": "GO:0030321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030321", "evidence": [ { "database": "UniProtKB", "id": "E9PTX9", "url": "https://www.uniprot.org/uniprotkb/E9PTX9" } ], "pmid": "" }, { "name": "T cell chemotaxis", "id": "GO:0010818", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010818", "evidence": [ { "database": "UniProtKB", "id": "E9PTX9", "url": "https://www.uniprot.org/uniprotkb/E9PTX9" } ], "pmid": "" }, { "name": "cellular response to potassium ion", "id": "GO:0035865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035865", "evidence": [ { "database": "UniProtKB", "id": "E9PTX9", "url": "https://www.uniprot.org/uniprotkb/E9PTX9" } ], "pmid": "" }, { "name": "branching involved in mammary gland duct morphogenesis", "id": "GO:0060444", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060444", "evidence": [ { "database": "UniProtKB", "id": "E9PTX9", "url": "https://www.uniprot.org/uniprotkb/E9PTX9" } ], "pmid": "" }, { "name": "mammary duct terminal end bud growth", "id": "GO:0060763", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060763", "evidence": [ { "database": "UniProtKB", "id": "E9PTX9", "url": "https://www.uniprot.org/uniprotkb/E9PTX9" } ], "pmid": "" }, { "name": "positive regulation of aspartate secretion", "id": "GO:1904450", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904450", "evidence": [ { "database": "UniProtKB", "id": "E9PTX9", "url": "https://www.uniprot.org/uniprotkb/E9PTX9" } ], "pmid": "" }, { "name": "maintenance of blood-brain barrier", "id": "GO:0035633", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035633", "evidence": [ { "database": "UniProtKB", "id": "E9PTX9", "url": "https://www.uniprot.org/uniprotkb/E9PTX9" } ], "pmid": "" }, { "name": "regulation of spontaneous synaptic transmission", "id": "GO:0150003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0150003", "evidence": [ { "database": "UniProtKB", "id": "E9PTX9", "url": "https://www.uniprot.org/uniprotkb/E9PTX9" } ], "pmid": "" }, { "name": "inorganic cation import across plasma membrane", "id": "GO:0098659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098659", "evidence": [ { "database": "UniProtKB", "id": "E9PTX9", "url": "https://www.uniprot.org/uniprotkb/E9PTX9" } ], "pmid": "" }, { "name": "sodium ion import across plasma membrane", "id": "GO:0098719", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098719", "evidence": [ { "database": "UniProtKB", "id": "E9PTX9", "url": "https://www.uniprot.org/uniprotkb/E9PTX9" } ], "pmid": "" }, { "name": "hyperosmotic response", "id": "GO:0006972", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006972", "evidence": [ { "database": "UniProtKB", "id": "E9PTX9", "url": "https://www.uniprot.org/uniprotkb/E9PTX9" } ], "pmid": "" }, { "name": "inorganic anion import across plasma membrane", "id": "GO:0098658", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098658", "evidence": [ { "database": "UniProtKB", "id": "E9PTX9", "url": "https://www.uniprot.org/uniprotkb/E9PTX9" } ], "pmid": "" }, { "name": "regulation of matrix metallopeptidase secretion", "id": "GO:1904464", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904464", "evidence": [ { "database": "UniProtKB", "id": "E9PTX9", "url": "https://www.uniprot.org/uniprotkb/E9PTX9" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E9PTX9", "url": "https://www.uniprot.org/uniprotkb/E9PTX9" } ], "pmid": "" }, { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "E9PTX9", "url": "https://www.uniprot.org/uniprotkb/E9PTX9" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "E9PTX9", "url": "https://www.uniprot.org/uniprotkb/E9PTX9" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "E9PTX9", "url": "https://www.uniprot.org/uniprotkb/E9PTX9" } ], "pmid": "" }, { "name": "cytoplasmic vesicle membrane", "id": "GO:0030659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030659", "evidence": [ { "database": "UniProtKB", "id": "E9PTX9", "url": "https://www.uniprot.org/uniprotkb/E9PTX9" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "E9PTX9", "url": "https://www.uniprot.org/uniprotkb/E9PTX9" } ], "pmid": "" }, { "name": "cell body", "id": "GO:0044297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044297", "evidence": [ { "database": "UniProtKB", "id": "E9PTX9", "url": "https://www.uniprot.org/uniprotkb/E9PTX9" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "E9PTX9", "url": "https://www.uniprot.org/uniprotkb/E9PTX9" } ], "pmid": "" }, { "name": "lateral plasma membrane", "id": "GO:0016328", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016328", "evidence": [ { "database": "UniProtKB", "id": "E9PTX9", "url": "https://www.uniprot.org/uniprotkb/E9PTX9" } ], "pmid": "" }, { "name": "cell projection", "id": "GO:0042995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042995", "evidence": [ { "database": "UniProtKB", "id": "E9PTX9", "url": "https://www.uniprot.org/uniprotkb/E9PTX9" } ], "pmid": "" }, { "name": "basal plasma membrane", "id": "GO:0009925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009925", "evidence": [ { "database": "UniProtKB", "id": "E9PTX9", "url": "https://www.uniprot.org/uniprotkb/E9PTX9" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "E9PTX9", "url": "https://www.uniprot.org/uniprotkb/E9PTX9" } ], "pmid": "" }, { "name": "protein-folding chaperone binding", "id": "GO:0051087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051087", "evidence": [ { "database": "UniProtKB", "id": "E9PTX9", "url": "https://www.uniprot.org/uniprotkb/E9PTX9" } ], "pmid": "" }, { "name": "Hsp90 protein binding", "id": "GO:0051879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051879", "evidence": [ { "database": "UniProtKB", "id": "E9PTX9", "url": "https://www.uniprot.org/uniprotkb/E9PTX9" } ], "pmid": "" }, { "name": "ammonium channel activity", "id": "GO:0008519", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008519", "evidence": [ { "database": "UniProtKB", "id": "E9PTX9", "url": "https://www.uniprot.org/uniprotkb/E9PTX9" } ], "pmid": "" }, { "name": "potassium ion transmembrane transporter activity", "id": "GO:0015079", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015079", "evidence": [ { "database": "UniProtKB", "id": "E9PTX9", "url": "https://www.uniprot.org/uniprotkb/E9PTX9" } ], "pmid": "" }, { "name": "sodium:potassium:chloride symporter activity", "id": "GO:0008511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008511", "evidence": [ { "database": "UniProtKB", "id": "E9PTX9", "url": "https://www.uniprot.org/uniprotkb/E9PTX9" } ], "pmid": "" }, { "name": "metal ion transmembrane transporter activity", "id": "GO:0046873", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046873", "evidence": [ { "database": "UniProtKB", "id": "E9PTX9", "url": "https://www.uniprot.org/uniprotkb/E9PTX9" } ], "pmid": "" }, { "name": "chloride:monoatomic cation symporter activity", "id": "GO:0015377", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015377", "evidence": [ { "database": "UniProtKB", "id": "E9PTX9", "url": "https://www.uniprot.org/uniprotkb/E9PTX9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "E9PTX9-1", "start_pos": "71", "end_pos": "71", "site_lbl": "Thr71", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 71, "start_aa": "Thr", "end_pos": 71, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr71", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "E9PTX9-1" }, { "uniprot_canonical_ac": "E9PTY0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "E9PTY0", "url": "https://www.uniprot.org/uniprotkb/E9PTY0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1010, "chemical_mass": 117502.0, "gene_names": "Lrrcc1;Lrrcc1;Sap2", "protein_name": "Leucine-rich repeat and coiled-coil domain-containing protein 1", "disease": [], "cellular_component": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "E9PTY0", "url": "https://www.uniprot.org/uniprotkb/E9PTY0" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "E9PTY0", "url": "https://www.uniprot.org/uniprotkb/E9PTY0" } ], "pmid": "" } ], "biological_process": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "E9PTY0", "url": "https://www.uniprot.org/uniprotkb/E9PTY0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "E9PTY0-1" }, { "uniprot_canonical_ac": "E9PTZ1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "E9PTZ1", "url": "https://www.uniprot.org/uniprotkb/E9PTZ1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1033, "chemical_mass": 110354.0, "gene_names": "Pear1;Pear1;RGD1305653", "protein_name": "Platelet endothelial aggregation receptor 1", "disease": [ { "disease_id": "DOID:1289", "name": "neurodegenerative disease", "description": "A central nervous system disease that results in the progressive deterioration of function or structure of neurons.", "url": "https://disease-ontology.org/term/DOID:1289", "evidence": [ { "id": "1289", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1289" } ], "weight": 0.0 }, { "disease_id": "DOID:423", "name": "myopathy", "description": "A muscular disease in which the muscle fibers do not function resulting in muscular weakness.", "url": "https://disease-ontology.org/term/DOID:423", "evidence": [ { "id": "423", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:423" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "phagocytic cup", "id": "GO:0001891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001891", "evidence": [ { "database": "UniProtKB", "id": "E9PTZ1", "url": "https://www.uniprot.org/uniprotkb/E9PTZ1" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E9PTZ1", "url": "https://www.uniprot.org/uniprotkb/E9PTZ1" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E9PTZ1", "url": "https://www.uniprot.org/uniprotkb/E9PTZ1" } ], "pmid": "" }, { "name": "lamellipodium", "id": "GO:0030027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030027", "evidence": [ { "database": "UniProtKB", "id": "E9PTZ1", "url": "https://www.uniprot.org/uniprotkb/E9PTZ1" } ], "pmid": "" } ], "biological_process": [ { "name": "platelet aggregation", "id": "GO:0070527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070527", "evidence": [ { "database": "UniProtKB", "id": "E9PTZ1", "url": "https://www.uniprot.org/uniprotkb/E9PTZ1" } ], "pmid": "" }, { "name": "phosphatidylinositol 3-kinase/protein kinase B signal transduction", "id": "GO:0043491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043491", "evidence": [ { "database": "UniProtKB", "id": "E9PTZ1", "url": "https://www.uniprot.org/uniprotkb/E9PTZ1" } ], "pmid": "" }, { "name": "positive regulation of platelet activation", "id": "GO:0010572", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010572", "evidence": [ { "database": "UniProtKB", "id": "E9PTZ1", "url": "https://www.uniprot.org/uniprotkb/E9PTZ1" } ], "pmid": "" }, { "name": "recognition of apoptotic cell", "id": "GO:0043654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043654", "evidence": [ { "database": "UniProtKB", "id": "E9PTZ1", "url": "https://www.uniprot.org/uniprotkb/E9PTZ1" } ], "pmid": "" } ], "molecular_function": [ { "name": "signaling receptor activity", "id": "GO:0038023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038023", "evidence": [ { "database": "UniProtKB", "id": "E9PTZ1", "url": "https://www.uniprot.org/uniprotkb/E9PTZ1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "E9PTZ1-1" }, { "uniprot_canonical_ac": "E9PTZ7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "E9PTZ7", "url": "https://www.uniprot.org/uniprotkb/E9PTZ7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 350, "chemical_mass": 39731.0, "gene_names": "Rt1-ec3;ENSRNOG00000069480;RT1-A2n;RT1-A2;RT1.A2(N);RT1A-2", "protein_name": "", "disease": [ { "disease_id": "DOID:0050426", "name": "Stevens-Johnson syndrome", "description": "A skin disease that is characterized by ulceration of less than 10 percent of the surface area of the body. The disease is often precipitated by the use of medications, such as antibiotics or antiepileptics, or onset of infection.", "url": "https://disease-ontology.org/term/DOID:0050426", "evidence": [ { "id": "0050426", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050426" } ], "weight": 0.0 }, { "disease_id": "DOID:0060180", "name": "colitis", "description": "An inflammatory bowel disease that involves inflammation located_in colon.", "url": "https://disease-ontology.org/term/DOID:0060180", "evidence": [ { "id": "0060180", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060180" } ], "weight": 0.0 }, { "disease_id": "DOID:0080160", "name": "Cytomegalovirus retinitis", "description": "A retinitis that has_material_basis_in Cytomegalovirus.", "url": "https://disease-ontology.org/term/DOID:0080160", "evidence": [ { "id": "0080160", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080160" } ], "weight": 0.0 }, { "disease_id": "DOID:0080600", "name": "COVID-19", "description": "A Coronavirus infectious disease that is characterized by fever, cough and shortness of breath and that has_material_basis_in Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a subtype of Betacoronavirus pandemicum.", "url": "https://disease-ontology.org/term/DOID:0080600", "evidence": [ { "id": "0080600", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080600" } ], "weight": 0.0 }, { "disease_id": "DOID:0080603", "name": "ankylosing spondylitis 1", "description": "A ankylosing spondylitis that has_material_basis_in variation in the HLA-B27 allele on chromosome 6p21.3.", "url": "https://disease-ontology.org/term/DOID:0080603", "evidence": [ { "id": "0080603", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080603" } ], "weight": 0.0 }, { "disease_id": "DOID:0080750", "name": "erythema nodosum", "description": "A panniculitis that is characterized by sudden onset of painful, erythematous, subcutaneous nodules mainly localized to the pretibial areas. Lesions are usually bilateral and symmetrical, ranging from 1 to 5 cm in diameter.", "url": "https://disease-ontology.org/term/DOID:0080750", "evidence": [ { "id": "0080750", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080750" } ], "weight": 0.0 }, { "disease_id": "DOID:0080820", "name": "occupational asthma", "description": "An environmental induced asthma that is characterized by a variable airflow limitation due to exposure to inhaled irritants in the workplace.", "url": "https://disease-ontology.org/term/DOID:0080820", "evidence": [ { "id": "0080820", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080820" } ], "weight": 0.0 }, { "disease_id": "DOID:0111079", "name": "birdshot chorioretinopathy", "description": "A posterior uveitis characterized by multiple small, hypopigmented, cream-colored choroidal lesions scattered symmetrically in the fundus primarily around the optic disc that presents in patients as blurred vision, floaters, photopsia, scotoma and nyctalopia.", "url": "https://disease-ontology.org/term/DOID:0111079", "evidence": [ { "id": "0111079", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111079" } ], "weight": 0.0 }, { "disease_id": "DOID:0111286", "name": "psoriasis 1", "description": "A psoriasis that has_material_basis_in variation in the HLA-C gene on chromosome 6p21.33.", "url": "https://disease-ontology.org/term/DOID:0111286", "evidence": [ { "id": "0111286", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111286" } ], "weight": 0.0 }, { "disease_id": "DOID:10003", "name": "sensorineural hearing loss", "description": "An inner ear disease that is characterized by hearing loss resulting from damage to the cochlea, auditory nerve and/or brainstem.", "url": "https://disease-ontology.org/term/DOID:10003", "evidence": [ { "id": "10003", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10003" } ], "weight": 0.0 }, { "disease_id": "DOID:1123", "name": "spondyloarthropathy", "description": "", "url": "https://disease-ontology.org/term/DOID:1123", "evidence": [ { "id": "1123", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1123" } ], "weight": 0.0 }, { "disease_id": "DOID:11265", "name": "trachoma", "description": "A commensal bacterial infectious disease that results_in infection located_in eye, has_material_basis_in Chlamydia trachomatis (A, B, Ba and C serovars), which is transmitted_by contact with eye discharge from the infected person and transmitted_by congenital method. The infection causes eyelid to turn inward which makes eyelashes to scratch the cornea.", "url": "https://disease-ontology.org/term/DOID:11265", "evidence": [ { "id": "11265", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11265" } ], "weight": 0.0 }, { "disease_id": "DOID:11335", "name": "sarcoidosis", "description": "A hypersensitivity reaction type IV disease characterized by the growth of collections of inflammatory cells (granulomas) in multiple organs.", "url": "https://disease-ontology.org/term/DOID:11335", "evidence": [ { "id": "11335", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11335" } ], "weight": 0.0 }, { "disease_id": "DOID:11563", "name": "retinal vasculitis", "description": "A vasculitis that is characterized by inflammation of the vascular branches of the retinal artery and has_symptom painless decrease of visual acuity, visual floaters, dark spot in vision, decreased ability to distinguish colors, and distortion of images such as linear images.", "url": "https://disease-ontology.org/term/DOID:11563", "evidence": [ { "id": "11563", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11563" } ], "weight": 0.0 }, { "disease_id": "DOID:12185", "name": "otosclerosis", "description": "An otitis interna characterized by isolated endochondral bone sclerosis of the labyrinthine capsule.", "url": "https://disease-ontology.org/term/DOID:12185", "evidence": [ { "id": "12185", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12185" } ], "weight": 0.0 }, { "disease_id": "DOID:12361", "name": "Graves' disease", "description": "An autoimmune disease of endocrine system that involves production of excessive amount of thyroid hormones, located_in thyroid gland.", "url": "https://disease-ontology.org/term/DOID:12361", "evidence": [ { "id": "12361", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12361" } ], "weight": 0.0 }, { "disease_id": "DOID:1273", "name": "respiratory syncytial virus infectious disease", "description": "A viral infectious disease that results_in infection located_in upper respiratory tract or located_in lower respiratory tract, has_material_basis_in Human respiratory syncytial virus (Orthopneumovirus hominis), which is transmitted_by droplet spread of nasal secretions from an infected person while coughing or sneezing, or transmitted_by contaminated fomites. The infection has_symptom runny nose, has_symptom fever, has_symptom cough, has_symptom wheezing, and has_symptom respiratory distress.", "url": "https://disease-ontology.org/term/DOID:1273", "evidence": [ { "id": "1273", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1273" } ], "weight": 0.0 }, { "disease_id": "DOID:13025", "name": "retinopathy of prematurity", "description": "", "url": "https://disease-ontology.org/term/DOID:13025", "evidence": [ { "id": "13025", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13025" } ], "weight": 0.0 }, { "disease_id": "DOID:13141", "name": "uveitis", "description": "An uveal disease is characterized by inflammation of any of the layers of the uvea of the eye, which includes the iris, ciliary body, and choroid.", "url": "https://disease-ontology.org/term/DOID:13141", "evidence": [ { "id": "13141", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13141" } ], "weight": 0.0 }, { "disease_id": "DOID:13241", "name": "Behcet's disease", "description": "An autoimmune disease that is characterized by mucocutaneous manifestations, including recurrent oral and genital ulcerations, ocular manifestations, especially chronic relapsing uveitis, and systemic vasculitis involving arteries and veins of all sizes.", "url": "https://disease-ontology.org/term/DOID:13241", "evidence": [ { "id": "13241", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13241" } ], "weight": 0.0 }, { "disease_id": "DOID:1407", "name": "anterior uveitis", "description": "", "url": "https://disease-ontology.org/term/DOID:1407", "evidence": [ { "id": "1407", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1407" } ], "weight": 0.0 }, { "disease_id": "DOID:1485", "name": "cystic fibrosis", "description": "A syndrome that is characterized by the buildup of thick, sticky mucus that can damage many organs.", "url": "https://disease-ontology.org/term/DOID:1485", "evidence": [ { "id": "1485", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1485" } ], "weight": 0.0 }, { "disease_id": "DOID:1883", "name": "hepatitis C", "description": "A viral hepatitis that results_in inflammation located_in liver, has_material_basis_in hepatitis C virus (Hepacivirus hominis), which is transmitted_by blood from an infected person enters the body of an uninfected person. The infection has_symptom fever, has_symptom fatigue, has_symptom loss of appetite, has_symptom nausea, has_symptom vomiting, has_symptom abdominal pain, has_symptom clay-colored bowel movements, has_symptom joint pain, and has_symptom jaundice.", "url": "https://disease-ontology.org/term/DOID:1883", "evidence": [ { "id": "1883", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1883" } ], "weight": 0.0 }, { "disease_id": "DOID:2508", "name": "Takayasu's arteritis", "description": "A vasculitis that involves inflammation of the aorta that carries blood from the heart to the rest of the body.", "url": "https://disease-ontology.org/term/DOID:2508", "evidence": [ { "id": "2508", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2508" } ], "weight": 0.0 }, { "disease_id": "DOID:2703", "name": "synovitis", "description": "A connective tissue disease that results_in inflammation located_in synovial membrane that lines a synovial joint which causes pain and swelling.", "url": "https://disease-ontology.org/term/DOID:2703", "evidence": [ { "id": "2703", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2703" } ], "weight": 0.0 }, { "disease_id": "DOID:2723", "name": "dermatitis", "description": "A skin disease characterized by itchy, erythematous, vesicular, weeping and crusting patches of skin.", "url": "https://disease-ontology.org/term/DOID:2723", "evidence": [ { "id": "2723", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2723" } ], "weight": 0.0 }, { "disease_id": "DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.", "url": "https://disease-ontology.org/term/DOID:2841", "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ], "weight": 0.0 }, { "disease_id": "DOID:2945", "name": "severe acute respiratory syndrome", "description": "A Coronavirus infectious disease that results_in infection located_in respiratory tract, has_material_basis_in Severe acute respiratory syndrome coronavirus (SARS-CoV or SARS-CoV-1), a subtype of Betacoronavirus pandemicum, which is transmitted_by droplet spread of respiratory secretions, transmitted_by ingestion of contaminated food, or transmitted_by fomites. The infection has_symptom fever, has_symptom headache, has_symptom body aches, has_symptom dry cough, and has_symptom hypoxia.", "url": "https://disease-ontology.org/term/DOID:2945", "evidence": [ { "id": "2945", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2945" } ], "weight": 0.0 }, { "disease_id": "DOID:3526", "name": "cerebral infarction", "description": "A cerebrovascular disease that is characterized by an area of necrotic tissue in the brain resulting from a blockage or narrowing in the arteries supplying blood and oxygen to the brain.", "url": "https://disease-ontology.org/term/DOID:3526", "evidence": [ { "id": "3526", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3526" } ], "weight": 0.0 }, { "disease_id": "DOID:3611", "name": "acute retinal necrosis syndrome", "description": "", "url": "https://disease-ontology.org/term/DOID:3611", "evidence": [ { "id": "3611", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3611" } ], "weight": 0.0 }, { "disease_id": "DOID:3875", "name": "thrombophlebitis", "description": "A phlebitis that results from a blood clot in the vessel.", "url": "https://disease-ontology.org/term/DOID:3875", "evidence": [ { "id": "3875", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3875" } ], "weight": 0.0 }, { "disease_id": "DOID:399", "name": "tuberculosis", "description": "A primary bacterial infectious disease that is located_in lungs, located_in lymph nodes, located_in pericardium, located_in brain, located_in pleura or located_in gastrointestinal tract, has_material_basis_in Mycobacterium tuberculosis, which is transmitted_by droplets released into the air when an infected person coughs or sneezes.", "url": "https://disease-ontology.org/term/DOID:399", "evidence": [ { "id": "399", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:399" } ], "weight": 0.0 }, { "disease_id": "DOID:4362", "name": "cervical cancer", "description": "A female reproductive organ cancer that is located_in the cervix.", "url": "https://disease-ontology.org/term/DOID:4362", "evidence": [ { "id": "4362", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4362" } ], "weight": 0.0 }, { "disease_id": "DOID:4481", "name": "allergic rhinitis", "description": "A rhinitis that is an allergic inflammation and irritation of the nasal airways involving sneezing, runny nose, nasal congestion, itching and tearing of the eyes caused by exposure to an allergen such as pollen, dust, mold, animal dander and droppings of cockroaches or house dust mites.", "url": "https://disease-ontology.org/term/DOID:4481", "evidence": [ { "id": "4481", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4481" } ], "weight": 0.0 }, { "disease_id": "DOID:526", "name": "human immunodeficiency virus infectious disease", "description": "A viral infectious disease that results in destruction of immune system, leading to life-threatening opportunistic infections and cancers, has_material_basis_in Human immunodeficiency virus 1 (Lentivirus humimdef1) or Human immunodeficiency virus 2 (Lentivirus humimdef2), which are transmitted by sexual contact, transmitted by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted by congenital method, and transmitted by contaminated needles. The virus infects helper T cells (CD4+ T cells) which are directly or indirectly destroyed, macrophages, and dendritic cells. The infection has symptom diarrhea, has symptom fatigue, has symptom fever, has symptom vaginal yeast infection, has symptom headache, has symptom mouth sores, has symptom muscle aches, has symptom sore throat, and has symptom swollen lymph glands.", "url": "https://disease-ontology.org/term/DOID:526", "evidence": [ { "id": "526", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:526" } ], "weight": 0.0 }, { "disease_id": "DOID:6039", "name": "uveal melanoma", "description": "A uveal cancer that has_material_basis_in uvea pigment cells.", "url": "https://disease-ontology.org/term/DOID:6039", "evidence": [ { "id": "6039", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6039" } ], "weight": 0.0 }, { "disease_id": "DOID:6196", "name": "reactive arthritis", "description": "An arthritis that is an autoimmune disease which develops due to an infection located elsewhere in the body.", "url": "https://disease-ontology.org/term/DOID:6196", "evidence": [ { "id": "6196", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6196" } ], "weight": 0.0 }, { "disease_id": "DOID:633", "name": "myositis", "description": "A myopathy characterized by muscle inflammation.", "url": "https://disease-ontology.org/term/DOID:633", "evidence": [ { "id": "633", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:633" } ], "weight": 0.0 }, { "disease_id": "DOID:7147", "name": "ankylosing spondylitis", "description": "An arthritis that results_in inflammation in the joints of the spine and pelvis. The disease has_symptom pain, has_symptom stiffness in the spine, has_symptom stiffness in the neck, has_symptom stiffness in the hips, has_symptom stiffness in the jaw and has_symptom stiffness in the rib cage.", "url": "https://disease-ontology.org/term/DOID:7147", "evidence": [ { "id": "7147", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7147" } ], "weight": 0.0 }, { "disease_id": "DOID:8947", "name": "diabetic retinopathy", "description": "", "url": "https://disease-ontology.org/term/DOID:8947", "evidence": [ { "id": "8947", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8947" } ], "weight": 0.0 }, { "disease_id": "DOID:9415", "name": "allergic asthma", "description": "An extrinsic asthma that is characterized by symptoms that are triggered by an allergic reaction caused by inhaled allergens such as dust mite allergen, pet dander, pollen and mold. The disease has_symptom coughing, has_symptom wheezing, has_symptom shortness of breath or has_symptom rapid breathing, and has_symptom chest tightness.", "url": "https://disease-ontology.org/term/DOID:9415", "evidence": [ { "id": "9415", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9415" } ], "weight": 0.0 }, { "disease_id": "DOID:9849", "name": "Meniere's disease", "description": "A vestibular disease characterized by vertigo, low-pitched tinnitus and hearing loss.", "url": "https://disease-ontology.org/term/DOID:9849", "evidence": [ { "id": "9849", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9849" } ], "weight": 0.0 }, { "disease_id": "DOID:987", "name": "alopecia", "description": "A hypotrichosis that is characterized by a loss of hair from the head or body.", "url": "https://disease-ontology.org/term/DOID:987", "evidence": [ { "id": "987", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:987" } ], "weight": 0.0 }, { "disease_id": "DOID:988", "name": "mitral valve prolapse", "description": "A mitral valve disease where one or both of the cusps of the mitral valve bulge or collapse backward in the left atrium during systole.", "url": "https://disease-ontology.org/term/DOID:988", "evidence": [ { "id": "988", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:988" } ], "weight": 0.0 } ], "biological_process": [ { "name": "antigen processing and presentation of endogenous peptide antigen via MHC class Ib", "id": "GO:0002476", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002476", "evidence": [ { "database": "UniProtKB", "id": "E9PTZ7", "url": "https://www.uniprot.org/uniprotkb/E9PTZ7" } ], "pmid": "" }, { "name": "regulation of natural killer cell mediated immunity", "id": "GO:0002715", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002715", "evidence": [ { "database": "UniProtKB", "id": "E9PTZ7", "url": "https://www.uniprot.org/uniprotkb/E9PTZ7" } ], "pmid": "" }, { "name": "positive regulation of natural killer cell mediated immunity", "id": "GO:0002717", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002717", "evidence": [ { "database": "UniProtKB", "id": "E9PTZ7", "url": "https://www.uniprot.org/uniprotkb/E9PTZ7" } ], "pmid": "" }, { "name": "positive regulation of interleukin-13 production", "id": "GO:0032736", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032736", "evidence": [ { "database": "UniProtKB", "id": "E9PTZ7", "url": "https://www.uniprot.org/uniprotkb/E9PTZ7" } ], "pmid": "" }, { "name": "positive regulation of TRAIL production", "id": "GO:0032759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032759", "evidence": [ { "database": "UniProtKB", "id": "E9PTZ7", "url": "https://www.uniprot.org/uniprotkb/E9PTZ7" } ], "pmid": "" }, { "name": "CD8-positive, alpha-beta T cell activation", "id": "GO:0036037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036037", "evidence": [ { "database": "UniProtKB", "id": "E9PTZ7", "url": "https://www.uniprot.org/uniprotkb/E9PTZ7" } ], "pmid": "" }, { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "E9PTZ7", "url": "https://www.uniprot.org/uniprotkb/E9PTZ7" } ], "pmid": "" }, { "name": "antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent", "id": "GO:0002486", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002486", "evidence": [ { "database": "UniProtKB", "id": "E9PTZ7", "url": "https://www.uniprot.org/uniprotkb/E9PTZ7" } ], "pmid": "" }, { "name": "negative regulation of T cell proliferation", "id": "GO:0042130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042130", "evidence": [ { "database": "UniProtKB", "id": "E9PTZ7", "url": "https://www.uniprot.org/uniprotkb/E9PTZ7" } ], "pmid": "" }, { "name": "protection from natural killer cell mediated cytotoxicity", "id": "GO:0042270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042270", "evidence": [ { "database": "UniProtKB", "id": "E9PTZ7", "url": "https://www.uniprot.org/uniprotkb/E9PTZ7" } ], "pmid": "" }, { "name": "adaptive immune response", "id": "GO:0002250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002250", "evidence": [ { "database": "UniProtKB", "id": "E9PTZ7", "url": "https://www.uniprot.org/uniprotkb/E9PTZ7" } ], "pmid": "" }, { "name": "positive regulation of T cell mediated cytotoxicity", "id": "GO:0001916", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001916", "evidence": [ { "database": "UniProtKB", "id": "E9PTZ7", "url": "https://www.uniprot.org/uniprotkb/E9PTZ7" } ], "pmid": "" }, { "name": "positive regulation of tumor necrosis factor production", "id": "GO:0032760", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032760", "evidence": [ { "database": "UniProtKB", "id": "E9PTZ7", "url": "https://www.uniprot.org/uniprotkb/E9PTZ7" } ], "pmid": "" }, { "name": "positive regulation of CD8-positive, alpha-beta T cell proliferation", "id": "GO:2000566", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000566", "evidence": [ { "database": "UniProtKB", "id": "E9PTZ7", "url": "https://www.uniprot.org/uniprotkb/E9PTZ7" } ], "pmid": "" }, { "name": "positive regulation of CD8-positive, alpha-beta T cell activation", "id": "GO:2001187", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001187", "evidence": [ { "database": "UniProtKB", "id": "E9PTZ7", "url": "https://www.uniprot.org/uniprotkb/E9PTZ7" } ], "pmid": "" }, { "name": "inner ear development", "id": "GO:0048839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048839", "evidence": [ { "database": "UniProtKB", "id": "E9PTZ7", "url": "https://www.uniprot.org/uniprotkb/E9PTZ7" } ], "pmid": "" }, { "name": "negative regulation of natural killer cell mediated cytotoxicity", "id": "GO:0045953", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045953", "evidence": [ { "database": "UniProtKB", "id": "E9PTZ7", "url": "https://www.uniprot.org/uniprotkb/E9PTZ7" } ], "pmid": "" }, { "name": "positive regulation of natural killer cell mediated cytotoxicity", "id": "GO:0045954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045954", "evidence": [ { "database": "UniProtKB", "id": "E9PTZ7", "url": "https://www.uniprot.org/uniprotkb/E9PTZ7" } ], "pmid": "" }, { "name": "antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent", "id": "GO:0002489", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002489", "evidence": [ { "database": "UniProtKB", "id": "E9PTZ7", "url": "https://www.uniprot.org/uniprotkb/E9PTZ7" } ], "pmid": "" }, { "name": "positive regulation of interleukin-4 production", "id": "GO:0032753", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032753", "evidence": [ { "database": "UniProtKB", "id": "E9PTZ7", "url": "https://www.uniprot.org/uniprotkb/E9PTZ7" } ], "pmid": "" }, { "name": "positive regulation of natural killer cell cytokine production", "id": "GO:0002729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002729", "evidence": [ { "database": "UniProtKB", "id": "E9PTZ7", "url": "https://www.uniprot.org/uniprotkb/E9PTZ7" } ], "pmid": "" }, { "name": "positive regulation of natural killer cell proliferation", "id": "GO:0032819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032819", "evidence": [ { "database": "UniProtKB", "id": "E9PTZ7", "url": "https://www.uniprot.org/uniprotkb/E9PTZ7" } ], "pmid": "" }, { "name": "positive regulation of natural killer cell activation", "id": "GO:0032816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032816", "evidence": [ { "database": "UniProtKB", "id": "E9PTZ7", "url": "https://www.uniprot.org/uniprotkb/E9PTZ7" } ], "pmid": "" }, { "name": "positive regulation of immunoglobulin production", "id": "GO:0002639", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002639", "evidence": [ { "database": "UniProtKB", "id": "E9PTZ7", "url": "https://www.uniprot.org/uniprotkb/E9PTZ7" } ], "pmid": "" }, { "name": "antigen processing and presentation of exogenous peptide antigen via MHC class Ib", "id": "GO:0002477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002477", "evidence": [ { "database": "UniProtKB", "id": "E9PTZ7", "url": "https://www.uniprot.org/uniprotkb/E9PTZ7" } ], "pmid": "" }, { "name": "natural killer cell tolerance induction", "id": "GO:0002519", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002519", "evidence": [ { "database": "UniProtKB", "id": "E9PTZ7", "url": "https://www.uniprot.org/uniprotkb/E9PTZ7" } ], "pmid": "" }, { "name": "negative regulation of natural killer cell activation", "id": "GO:0032815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032815", "evidence": [ { "database": "UniProtKB", "id": "E9PTZ7", "url": "https://www.uniprot.org/uniprotkb/E9PTZ7" } ], "pmid": "" }, { "name": "positive regulation of antibody-dependent cellular cytotoxicity", "id": "GO:0001815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001815", "evidence": [ { "database": "UniProtKB", "id": "E9PTZ7", "url": "https://www.uniprot.org/uniprotkb/E9PTZ7" } ], "pmid": "" } ], "cellular_component": [ { "name": "MHC class Ib protein complex", "id": "GO:0032398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032398", "evidence": [ { "database": "UniProtKB", "id": "E9PTZ7", "url": "https://www.uniprot.org/uniprotkb/E9PTZ7" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "E9PTZ7", "url": "https://www.uniprot.org/uniprotkb/E9PTZ7" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E9PTZ7", "url": "https://www.uniprot.org/uniprotkb/E9PTZ7" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "E9PTZ7", "url": "https://www.uniprot.org/uniprotkb/E9PTZ7" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "E9PTZ7", "url": "https://www.uniprot.org/uniprotkb/E9PTZ7" } ], "pmid": "" }, { "name": "phagocytic vesicle membrane", "id": "GO:0030670", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030670", "evidence": [ { "database": "UniProtKB", "id": "E9PTZ7", "url": "https://www.uniprot.org/uniprotkb/E9PTZ7" } ], "pmid": "" }, { "name": "MHC class I protein complex", "id": "GO:0042612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042612", "evidence": [ { "database": "UniProtKB", "id": "E9PTZ7", "url": "https://www.uniprot.org/uniprotkb/E9PTZ7" } ], "pmid": "" }, { "name": "lumenal side of endoplasmic reticulum membrane", "id": "GO:0098553", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098553", "evidence": [ { "database": "UniProtKB", "id": "E9PTZ7", "url": "https://www.uniprot.org/uniprotkb/E9PTZ7" } ], "pmid": "" } ], "molecular_function": [ { "name": "natural killer cell lectin-like receptor binding", "id": "GO:0046703", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046703", "evidence": [ { "database": "UniProtKB", "id": "E9PTZ7", "url": "https://www.uniprot.org/uniprotkb/E9PTZ7" } ], "pmid": "" }, { "name": "signaling receptor binding", "id": "GO:0005102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005102", "evidence": [ { "database": "UniProtKB", "id": "E9PTZ7", "url": "https://www.uniprot.org/uniprotkb/E9PTZ7" } ], "pmid": "" }, { "name": "beta-2-microglobulin binding", "id": "GO:0030881", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030881", "evidence": [ { "database": "UniProtKB", "id": "E9PTZ7", "url": "https://www.uniprot.org/uniprotkb/E9PTZ7" } ], "pmid": "" }, { "name": "peptide antigen binding", "id": "GO:0042605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042605", "evidence": [ { "database": "UniProtKB", "id": "E9PTZ7", "url": "https://www.uniprot.org/uniprotkb/E9PTZ7" } ], "pmid": "" }, { "name": "T cell receptor binding", "id": "GO:0042608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042608", "evidence": [ { "database": "UniProtKB", "id": "E9PTZ7", "url": "https://www.uniprot.org/uniprotkb/E9PTZ7" } ], "pmid": "" }, { "name": "receptor ligand activity", "id": "GO:0048018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048018", "evidence": [ { "database": "UniProtKB", "id": "E9PTZ7", "url": "https://www.uniprot.org/uniprotkb/E9PTZ7" } ], "pmid": "" }, { "name": "MHC class I protein binding", "id": "GO:0042288", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042288", "evidence": [ { "database": "UniProtKB", "id": "E9PTZ7", "url": "https://www.uniprot.org/uniprotkb/E9PTZ7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "E9PTZ7-1" }, { "uniprot_canonical_ac": "F1LM38-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1LM38", "url": "https://www.uniprot.org/uniprotkb/F1LM38" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 613, "chemical_mass": 64688.0, "gene_names": "Khdc4;Blom7;Khdc4;RGD1565775", "protein_name": "KH homology domain-containing protein 4", "disease": [], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "F1LM38", "url": "https://www.uniprot.org/uniprotkb/F1LM38" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1LM38", "url": "https://www.uniprot.org/uniprotkb/F1LM38" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1LM38", "url": "https://www.uniprot.org/uniprotkb/F1LM38" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1LM38", "url": "https://www.uniprot.org/uniprotkb/F1LM38" } ], "pmid": "" }, { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "F1LM38", "url": "https://www.uniprot.org/uniprotkb/F1LM38" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA splice site recognition", "id": "GO:0006376", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006376", "evidence": [ { "database": "UniProtKB", "id": "F1LM38", "url": "https://www.uniprot.org/uniprotkb/F1LM38" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1LM38-1" }, { "uniprot_canonical_ac": "F1LM66-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1LM66", "url": "https://www.uniprot.org/uniprotkb/F1LM66" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 969, "chemical_mass": 109102.0, "gene_names": "Eftud2", "protein_name": "116 kDa U5 small nuclear ribonucleoprotein component", "disease": [ { "disease_id": "DOID:0080196", "name": "mandibulofacial dysostosis, Guion-Almeida type", "description": "A syndrome characterized by progressive microcephaly, micrognathia, microtia, dysplastic ears, preauricular skin tags, speech delay, significant developmental delay, midface and malar hypoplasia.", "url": "https://disease-ontology.org/term/DOID:0080196", "evidence": [ { "id": "0080196", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080196" } ], "weight": 0.0 }, { "disease_id": "DOID:10485", "name": "esophageal atresia", "description": "", "url": "https://disease-ontology.org/term/DOID:10485", "evidence": [ { "id": "10485", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10485" } ], "weight": 0.0 }, { "disease_id": "DOID:10907", "name": "microcephaly", "description": "A congenital nervous system abnormality that is characterized by a significantly smaller than normal head in infants.", "url": "https://disease-ontology.org/term/DOID:10907", "evidence": [ { "id": "10907", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10907" } ], "weight": 0.0 }, { "disease_id": "DOID:2043", "name": "hepatitis B", "description": "A viral hepatitis that results_in inflammation located_in liver, has_material_basis_in Hepatitis B virus (Orthohepadnavirus hominoidei), which is transmitted_by sexual contact, blood transfusions, or fomites like needles or syringes. The infection has_symptom fever, fatigue, loss of appetite, nausea, vomiting, abdominal pain, clay-colored bowel movements, joint pain, and jaundice.", "url": "https://disease-ontology.org/term/DOID:2043", "evidence": [ { "id": "2043", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2043" } ], "weight": 0.0 }, { "disease_id": "DOID:2908", "name": "Treacher Collins syndrome", "description": "A syndrome that is characterized by bilateral and symmetric downslanting palpebral fissures, malar hypoplasia, micrognathia, and external ear abnormalities.", "url": "https://disease-ontology.org/term/DOID:2908", "evidence": [ { "id": "2908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2908" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "F1LM66", "url": "https://www.uniprot.org/uniprotkb/F1LM66" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "F1LM66", "url": "https://www.uniprot.org/uniprotkb/F1LM66" } ], "pmid": "" }, { "name": "U5 snRNA binding", "id": "GO:0030623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030623", "evidence": [ { "database": "UniProtKB", "id": "F1LM66", "url": "https://www.uniprot.org/uniprotkb/F1LM66" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1LM66", "url": "https://www.uniprot.org/uniprotkb/F1LM66" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1LM66", "url": "https://www.uniprot.org/uniprotkb/F1LM66" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1LM66", "url": "https://www.uniprot.org/uniprotkb/F1LM66" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "F1LM66", "url": "https://www.uniprot.org/uniprotkb/F1LM66" } ], "pmid": "" }, { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "F1LM66", "url": "https://www.uniprot.org/uniprotkb/F1LM66" } ], "pmid": "" }, { "name": "Cajal body", "id": "GO:0015030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015030", "evidence": [ { "database": "UniProtKB", "id": "F1LM66", "url": "https://www.uniprot.org/uniprotkb/F1LM66" } ], "pmid": "" }, { "name": "catalytic step 2 spliceosome", "id": "GO:0071013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071013", "evidence": [ { "database": "UniProtKB", "id": "F1LM66", "url": "https://www.uniprot.org/uniprotkb/F1LM66" } ], "pmid": "" }, { "name": "precatalytic spliceosome", "id": "GO:0071011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071011", "evidence": [ { "database": "UniProtKB", "id": "F1LM66", "url": "https://www.uniprot.org/uniprotkb/F1LM66" } ], "pmid": "" }, { "name": "post-mRNA release spliceosomal complex", "id": "GO:0071014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071014", "evidence": [ { "database": "UniProtKB", "id": "F1LM66", "url": "https://www.uniprot.org/uniprotkb/F1LM66" } ], "pmid": "" }, { "name": "U2-type catalytic step 1 spliceosome", "id": "GO:0071006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071006", "evidence": [ { "database": "UniProtKB", "id": "F1LM66", "url": "https://www.uniprot.org/uniprotkb/F1LM66" } ], "pmid": "" }, { "name": "U2-type catalytic step 2 spliceosome", "id": "GO:0071007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071007", "evidence": [ { "database": "UniProtKB", "id": "F1LM66", "url": "https://www.uniprot.org/uniprotkb/F1LM66" } ], "pmid": "" }, { "name": "U4/U6 x U5 tri-snRNP complex", "id": "GO:0046540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046540", "evidence": [ { "database": "UniProtKB", "id": "F1LM66", "url": "https://www.uniprot.org/uniprotkb/F1LM66" } ], "pmid": "" }, { "name": "post-spliceosomal complex", "id": "GO:0071020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071020", "evidence": [ { "database": "UniProtKB", "id": "F1LM66", "url": "https://www.uniprot.org/uniprotkb/F1LM66" } ], "pmid": "" }, { "name": "U2-type precatalytic spliceosome", "id": "GO:0071005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071005", "evidence": [ { "database": "UniProtKB", "id": "F1LM66", "url": "https://www.uniprot.org/uniprotkb/F1LM66" } ], "pmid": "" }, { "name": "U12-type precatalytic spliceosome", "id": "GO:0071016", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071016", "evidence": [ { "database": "UniProtKB", "id": "F1LM66", "url": "https://www.uniprot.org/uniprotkb/F1LM66" } ], "pmid": "" }, { "name": "U12-type catalytic step 2 spliceosome", "id": "GO:0071018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071018", "evidence": [ { "database": "UniProtKB", "id": "F1LM66", "url": "https://www.uniprot.org/uniprotkb/F1LM66" } ], "pmid": "" } ], "biological_process": [ { "name": "cellular response to xenobiotic stimulus", "id": "GO:0071466", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071466", "evidence": [ { "database": "UniProtKB", "id": "F1LM66", "url": "https://www.uniprot.org/uniprotkb/F1LM66" } ], "pmid": "" }, { "name": "response to cocaine", "id": "GO:0042220", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042220", "evidence": [ { "database": "UniProtKB", "id": "F1LM66", "url": "https://www.uniprot.org/uniprotkb/F1LM66" } ], "pmid": "" }, { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "F1LM66", "url": "https://www.uniprot.org/uniprotkb/F1LM66" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1LM66-1" }, { "uniprot_canonical_ac": "F1LMA5-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1LMA5", "url": "https://www.uniprot.org/uniprotkb/F1LMA5" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 284, "chemical_mass": 32360.0, "gene_names": "Fv1;Fv1;RGD1309326", "protein_name": "", "disease": [], "cellular_component": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "F1LMA5", "url": "https://www.uniprot.org/uniprotkb/F1LMA5" } ], "pmid": "" } ], "biological_process": [ { "name": "response to virus", "id": "GO:0009615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009615", "evidence": [ { "database": "UniProtKB", "id": "F1LMA5", "url": "https://www.uniprot.org/uniprotkb/F1LMA5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1LMA5-1" }, { "uniprot_canonical_ac": "F1LMC1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1LMC1", "url": "https://www.uniprot.org/uniprotkb/F1LMC1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 575, "chemical_mass": 61011.0, "gene_names": "Wtip", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1LMC1", "url": "https://www.uniprot.org/uniprotkb/F1LMC1" } ], "pmid": "" }, { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "F1LMC1", "url": "https://www.uniprot.org/uniprotkb/F1LMC1" } ], "pmid": "" }, { "name": "P-body", "id": "GO:0000932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000932", "evidence": [ { "database": "UniProtKB", "id": "F1LMC1", "url": "https://www.uniprot.org/uniprotkb/F1LMC1" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "F1LMC1", "url": "https://www.uniprot.org/uniprotkb/F1LMC1" } ], "pmid": "" }, { "name": "anchoring junction", "id": "GO:0070161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070161", "evidence": [ { "database": "UniProtKB", "id": "F1LMC1", "url": "https://www.uniprot.org/uniprotkb/F1LMC1" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1LMC1", "url": "https://www.uniprot.org/uniprotkb/F1LMC1" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "F1LMC1", "url": "https://www.uniprot.org/uniprotkb/F1LMC1" } ], "pmid": "" } ], "biological_process": [ { "name": "response to hypoxia", "id": "GO:0001666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001666", "evidence": [ { "database": "UniProtKB", "id": "F1LMC1", "url": "https://www.uniprot.org/uniprotkb/F1LMC1" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "F1LMC1", "url": "https://www.uniprot.org/uniprotkb/F1LMC1" } ], "pmid": "" }, { "name": "cytoskeleton organization", "id": "GO:0007010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007010", "evidence": [ { "database": "UniProtKB", "id": "F1LMC1", "url": "https://www.uniprot.org/uniprotkb/F1LMC1" } ], "pmid": "" }, { "name": "miRNA-mediated gene silencing by inhibition of translation", "id": "GO:0035278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035278", "evidence": [ { "database": "UniProtKB", "id": "F1LMC1", "url": "https://www.uniprot.org/uniprotkb/F1LMC1" } ], "pmid": "" }, { "name": "miRNA-mediated post-transcriptional gene silencing", "id": "GO:0035195", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035195", "evidence": [ { "database": "UniProtKB", "id": "F1LMC1", "url": "https://www.uniprot.org/uniprotkb/F1LMC1" } ], "pmid": "" }, { "name": "negative regulation of hippo signaling", "id": "GO:0035331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035331", "evidence": [ { "database": "UniProtKB", "id": "F1LMC1", "url": "https://www.uniprot.org/uniprotkb/F1LMC1" } ], "pmid": "" }, { "name": "regulatory ncRNA-mediated gene silencing", "id": "GO:0031047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031047", "evidence": [ { "database": "UniProtKB", "id": "F1LMC1", "url": "https://www.uniprot.org/uniprotkb/F1LMC1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "F1LMC1-1", "start_pos": "313", "end_pos": "313", "site_lbl": "Thr313", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 313, "start_aa": "Thr", "end_pos": 313, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr313", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "F1LMC1-1" }, { "uniprot_canonical_ac": "P0DSP1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 2215, "chemical_mass": 247316.0, "gene_names": "Sorl1;Lr11;RGD619914;SorLA;Sorl1", "protein_name": "Sortilin-related receptor", "disease": [ { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 } ], "biological_process": [ { "name": "negative regulation of cytokine-mediated signaling pathway", "id": "GO:0001960", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001960", "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ], "pmid": "" }, { "name": "positive regulation of protein localization to early endosome", "id": "GO:1902966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902966", "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ], "pmid": "" }, { "name": "positive regulation of adipose tissue development", "id": "GO:1904179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904179", "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ], "pmid": "" }, { "name": "protein retention in Golgi apparatus", "id": "GO:0045053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045053", "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ], "pmid": "" }, { "name": "neuropeptide signaling pathway", "id": "GO:0007218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007218", "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ], "pmid": "" }, { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ], "pmid": "" }, { "name": "protein targeting", "id": "GO:0006605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006605", "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ], "pmid": "" }, { "name": "regulation of smooth muscle cell migration", "id": "GO:0014910", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014910", "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ], "pmid": "" }, { "name": "negative regulation of amyloid-beta formation", "id": "GO:1902430", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902430", "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ], "pmid": "" }, { "name": "negative regulation of BMP signaling pathway", "id": "GO:0030514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030514", "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ], "pmid": "" }, { "name": "diet induced thermogenesis", "id": "GO:0002024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002024", "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ], "pmid": "" }, { "name": "receptor-mediated endocytosis", "id": "GO:0006898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006898", "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ], "pmid": "" }, { "name": "negative regulation of protein-containing complex assembly", "id": "GO:0031333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031333", "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ], "pmid": "" }, { "name": "positive regulation of protein catabolic process", "id": "GO:0045732", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045732", "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ], "pmid": "" }, { "name": "protein targeting to lysosome", "id": "GO:0006622", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006622", "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ], "pmid": "" }, { "name": "post-Golgi vesicle-mediated transport", "id": "GO:0006892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006892", "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ], "pmid": "" }, { "name": "positive regulation of endocytic recycling", "id": "GO:2001137", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001137", "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ], "pmid": "" }, { "name": "retrograde transport, endosome to Golgi", "id": "GO:0042147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042147", "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ], "pmid": "" }, { "name": "positive regulation of insulin receptor signaling pathway", "id": "GO:0046628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046628", "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ], "pmid": "" }, { "name": "protein localization to Golgi apparatus", "id": "GO:0034067", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034067", "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ], "pmid": "" }, { "name": "negative regulation of neurogenesis", "id": "GO:0050768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050768", "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ], "pmid": "" }, { "name": "positive regulation of ER to Golgi vesicle-mediated transport", "id": "GO:1902953", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902953", "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ], "pmid": "" }, { "name": "negative regulation of triglyceride catabolic process", "id": "GO:0010897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010897", "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ], "pmid": "" }, { "name": "lysosomal protein catabolic process", "id": "GO:1905146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905146", "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ], "pmid": "" }, { "name": "positive regulation of protein exit from endoplasmic reticulum", "id": "GO:0070863", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070863", "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ], "pmid": "" }, { "name": "positive regulation of glial cell-derived neurotrophic factor production", "id": "GO:1900168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900168", "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ], "pmid": "" }, { "name": "positive regulation of early endosome to recycling endosome transport", "id": "GO:1902955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902955", "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ], "pmid": "" }, { "name": "negative regulation of neurofibrillary tangle assembly", "id": "GO:1902997", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902997", "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ], "pmid": "" }, { "name": "endosome to plasma membrane protein transport", "id": "GO:0099638", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099638", "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ], "pmid": "" }, { "name": "adaptive thermogenesis", "id": "GO:1990845", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990845", "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ], "pmid": "" }, { "name": "negative regulation of amyloid precursor protein catabolic process", "id": "GO:1902992", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902992", "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ], "pmid": "" }, { "name": "insulin receptor recycling", "id": "GO:0038020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038020", "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ], "pmid": "" }, { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ], "pmid": "" } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ], "pmid": "" }, { "name": "nuclear envelope lumen", "id": "GO:0005641", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005641", "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ], "pmid": "" }, { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ], "pmid": "" }, { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ], "pmid": "" }, { "name": "recycling endosome", "id": "GO:0055037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055037", "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ], "pmid": "" }, { "name": "transport vesicle membrane", "id": "GO:0030658", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030658", "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ], "pmid": "" }, { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ], "pmid": "" }, { "name": "recycling endosome membrane", "id": "GO:0055038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055038", "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ], "pmid": "" }, { "name": "multivesicular body", "id": "GO:0005771", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005771", "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ], "pmid": "" }, { "name": "multivesicular body membrane", "id": "GO:0032585", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032585", "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ], "pmid": "" }, { "name": "perinucleolar compartment", "id": "GO:0097356", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097356", "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ], "pmid": "" }, { "name": "Golgi cisterna", "id": "GO:0031985", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031985", "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ], "pmid": "" }, { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ], "pmid": "" } ], "molecular_function": [ { "name": "transmembrane signaling receptor activity", "id": "GO:0004888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004888", "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ], "pmid": "" }, { "name": "amyloid-beta binding", "id": "GO:0001540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001540", "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ], "pmid": "" }, { "name": "low-density lipoprotein particle binding", "id": "GO:0030169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030169", "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ], "pmid": "" }, { "name": "aspartic-type endopeptidase inhibitor activity", "id": "GO:0019828", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019828", "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ], "pmid": "" }, { "name": "cargo receptor activity", "id": "GO:0038024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038024", "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ], "pmid": "" }, { "name": "neuropeptide binding", "id": "GO:0042923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042923", "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ], "pmid": "" }, { "name": "protein transporter activity", "id": "GO:0140318", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140318", "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P0DSP1-1", "start_pos": "1035", "end_pos": "1035", "site_lbl": "Asn1035", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1035, "start_aa": "Asn", "end_pos": 1035, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1035", "evidence": [ { "id": "P0DSP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0DSP1#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P0DSP1-1", "start_pos": "1068", "end_pos": "1068", "site_lbl": "Asn1068", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1068, "start_aa": "Asn", "end_pos": 1068, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1068", "evidence": [ { "id": "P0DSP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0DSP1#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P0DSP1-1", "start_pos": "1164", "end_pos": "1164", "site_lbl": "Asn1164", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1164, "start_aa": "Asn", "end_pos": 1164, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1164", "evidence": [ { "id": "P0DSP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0DSP1#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P0DSP1-1", "start_pos": "1191", "end_pos": "1191", "site_lbl": "Asn1191", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1191, "start_aa": "Asn", "end_pos": 1191, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1191", "evidence": [ { "id": "P0DSP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0DSP1#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P0DSP1-1", "start_pos": "1246", "end_pos": "1246", "site_lbl": "Asn1246", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1246, "start_aa": "Asn", "end_pos": 1246, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1246", "evidence": [ { "id": "P0DSP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0DSP1#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P0DSP1-1", "start_pos": "1367", "end_pos": "1367", "site_lbl": "Asn1367", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1367, "start_aa": "Asn", "end_pos": 1367, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1367", "evidence": [ { "id": "P0DSP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0DSP1#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P0DSP1-1", "start_pos": "1413", "end_pos": "1413", "site_lbl": "Thr1413", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1413, "start_aa": "Thr", "end_pos": 1413, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1413", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "P0DSP1-1", "start_pos": "1458", "end_pos": "1458", "site_lbl": "Asn1458", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1458, "start_aa": "Asn", "end_pos": 1458, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1458", "evidence": [ { "id": "P0DSP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0DSP1#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P0DSP1-1", "start_pos": "158", "end_pos": "158", "site_lbl": "Asn158", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 158, "start_aa": "Asn", "end_pos": 158, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn158", "evidence": [ { "id": "P0DSP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0DSP1#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P0DSP1-1", "start_pos": "1608", "end_pos": "1608", "site_lbl": "Asn1608", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1608, "start_aa": "Asn", "end_pos": 1608, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1608", "evidence": [ { "id": "P0DSP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0DSP1#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P0DSP1-1", "start_pos": "1706", "end_pos": "1706", "site_lbl": "Asn1706", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1706, "start_aa": "Asn", "end_pos": 1706, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1706", "evidence": [ { "id": "P0DSP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0DSP1#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P0DSP1-1", "start_pos": "1733", "end_pos": "1733", "site_lbl": "Asn1733", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1733, "start_aa": "Asn", "end_pos": 1733, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1733", "evidence": [ { "id": "P0DSP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0DSP1#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P0DSP1-1", "start_pos": "1810", "end_pos": "1810", "site_lbl": "Asn1810", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1810, "start_aa": "Asn", "end_pos": 1810, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1810", "evidence": [ { "id": "P0DSP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0DSP1#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P0DSP1-1", "start_pos": "1855", "end_pos": "1855", "site_lbl": "Asn1855", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1855, "start_aa": "Asn", "end_pos": 1855, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1855", "evidence": [ { "id": "P0DSP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0DSP1#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P0DSP1-1", "start_pos": "1895", "end_pos": "1895", "site_lbl": "Asn1895", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1895, "start_aa": "Asn", "end_pos": 1895, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1895", "evidence": [ { "id": "P0DSP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0DSP1#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P0DSP1-1", "start_pos": "1987", "end_pos": "1987", "site_lbl": "Asn1987", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1987, "start_aa": "Asn", "end_pos": 1987, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1987", "evidence": [ { "id": "P0DSP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0DSP1#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P0DSP1-1", "start_pos": "2011", "end_pos": "2011", "site_lbl": "Asn2011", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 2011, "start_aa": "Asn", "end_pos": 2011, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn2011", "evidence": [ { "id": "P0DSP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0DSP1#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P0DSP1-1", "start_pos": "2055", "end_pos": "2055", "site_lbl": "Asn2055", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 2055, "start_aa": "Asn", "end_pos": 2055, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn2055", "evidence": [ { "id": "P0DSP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0DSP1#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P0DSP1-1", "start_pos": "2070", "end_pos": "2070", "site_lbl": "Asn2070", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 2070, "start_aa": "Asn", "end_pos": 2070, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn2070", "evidence": [ { "id": "P0DSP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0DSP1#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P0DSP1-1", "start_pos": "2077", "end_pos": "2077", "site_lbl": "Asn2077", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 2077, "start_aa": "Asn", "end_pos": 2077, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn2077", "evidence": [ { "id": "P0DSP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0DSP1#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P0DSP1-1", "start_pos": "2093", "end_pos": "2093", "site_lbl": "Asn2093", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 2093, "start_aa": "Asn", "end_pos": 2093, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn2093", "evidence": [ { "id": "P0DSP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0DSP1#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P0DSP1-1", "start_pos": "368", "end_pos": "368", "site_lbl": "Asn368", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 368, "start_aa": "Asn", "end_pos": 368, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn368", "evidence": [ { "id": "P0DSP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0DSP1#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P0DSP1-1", "start_pos": "430", "end_pos": "430", "site_lbl": "Asn430", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 430, "start_aa": "Asn", "end_pos": 430, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn430", "evidence": [ { "id": "P0DSP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0DSP1#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P0DSP1-1", "start_pos": "616", "end_pos": "616", "site_lbl": "Asn616", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 616, "start_aa": "Asn", "end_pos": 616, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn616", "evidence": [ { "id": "P0DSP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0DSP1#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P0DSP1-1", "start_pos": "674", "end_pos": "674", "site_lbl": "Asn674", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 674, "start_aa": "Asn", "end_pos": 674, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn674", "evidence": [ { "id": "P0DSP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0DSP1#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P0DSP1-1", "start_pos": "818", "end_pos": "818", "site_lbl": "Asn818", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 818, "start_aa": "Asn", "end_pos": 818, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn818", "evidence": [ { "id": "P0DSP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0DSP1#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P0DSP1-1", "start_pos": "871", "end_pos": "871", "site_lbl": "Asn871", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 871, "start_aa": "Asn", "end_pos": 871, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn871", "evidence": [ { "id": "P0DSP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0DSP1#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P0DSP1-1", "start_pos": "99", "end_pos": "99", "site_lbl": "Asn99", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 99, "start_aa": "Asn", "end_pos": 99, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn99", "evidence": [ { "id": "P0DSP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0DSP1#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P0DSP1-1", "start_pos": "114", "end_pos": "114", "site_lbl": "Ser114", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ] } ] }, { "uniprot_canonical_ac": "P0DSP1-1", "start_pos": "2207", "end_pos": "2207", "site_lbl": "Ser2207", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P0DSP1", "url": "https://www.uniprot.org/uniprotkb/P0DSP1" } ] } ] } ], "record_id": "P0DSP1-1" }, { "uniprot_canonical_ac": "A0A8I5ZZZ4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZZZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZZZ4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 321, "chemical_mass": 35099.0, "gene_names": "Rdm1;Rad52b;Rdm1", "protein_name": "RAD52 motif-containing protein 1", "disease": [], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZZZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZZZ4" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZZZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZZZ4" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZZZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZZZ4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZZZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZZZ4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZZZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZZZ4" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA recombination", "id": "GO:0006310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006310", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZZZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZZZ4" } ], "pmid": "" }, { "name": "double-strand break repair", "id": "GO:0006302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006302", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZZZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZZZ4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZZZ4-1" }, { "uniprot_canonical_ac": "A0A8I6A742-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A742", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A742" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 384, "chemical_mass": 44859.0, "gene_names": "Cers6;Cers6;Lass6;RGD1561599", "protein_name": "", "disease": [], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A742", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A742" } ], "pmid": "" }, { "name": "sphingosine N-acyltransferase activity", "id": "GO:0050291", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050291", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A742", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A742" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A742", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A742" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A742", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A742" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A742", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A742" } ], "pmid": "" } ], "biological_process": [ { "name": "ceramide biosynthetic process", "id": "GO:0046513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046513", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A742", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A742" } ], "pmid": "" }, { "name": "sphingolipid biosynthetic process", "id": "GO:0030148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030148", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A742", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A742" } ], "pmid": "" }, { "name": "oligodendrocyte development", "id": "GO:0014003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014003", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A742", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A742" } ], "pmid": "" }, { "name": "positive regulation of oligodendrocyte apoptotic process", "id": "GO:1900143", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900143", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A742", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A742" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6A742-1" }, { "uniprot_canonical_ac": "F1M8T7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1M8T7", "url": "https://www.uniprot.org/uniprotkb/F1M8T7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 365, "chemical_mass": 39664.0, "gene_names": "Cd5l;Fcrl1", "protein_name": "", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1M8T7", "url": "https://www.uniprot.org/uniprotkb/F1M8T7" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "F1M8T7", "url": "https://www.uniprot.org/uniprotkb/F1M8T7" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of complement activation", "id": "GO:0030449", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030449", "evidence": [ { "database": "UniProtKB", "id": "F1M8T7", "url": "https://www.uniprot.org/uniprotkb/F1M8T7" } ], "pmid": "" }, { "name": "positive regulation of complement-dependent cytotoxicity", "id": "GO:1903661", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903661", "evidence": [ { "database": "UniProtKB", "id": "F1M8T7", "url": "https://www.uniprot.org/uniprotkb/F1M8T7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1M8T7-1" }, { "uniprot_canonical_ac": "M0RDY6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "M0RDY6", "url": "https://www.uniprot.org/uniprotkb/M0RDY6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 2952, "chemical_mass": 325558.0, "gene_names": "Crybg3;Crybg3", "protein_name": "", "disease": [], "molecular_function": [ { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "M0RDY6", "url": "https://www.uniprot.org/uniprotkb/M0RDY6" } ], "pmid": "" }, { "name": "protein kinase A binding", "id": "GO:0051018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051018", "evidence": [ { "database": "UniProtKB", "id": "M0RDY6", "url": "https://www.uniprot.org/uniprotkb/M0RDY6" } ], "pmid": "" }, { "name": "structural constituent of eye lens", "id": "GO:0005212", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005212", "evidence": [ { "database": "UniProtKB", "id": "M0RDY6", "url": "https://www.uniprot.org/uniprotkb/M0RDY6" } ], "pmid": "" } ], "biological_process": [ { "name": "visual perception", "id": "GO:0007601", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007601", "evidence": [ { "database": "UniProtKB", "id": "M0RDY6", "url": "https://www.uniprot.org/uniprotkb/M0RDY6" } ], "pmid": "" }, { "name": "lens development in camera-type eye", "id": "GO:0002088", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002088", "evidence": [ { "database": "UniProtKB", "id": "M0RDY6", "url": "https://www.uniprot.org/uniprotkb/M0RDY6" } ], "pmid": "" } ], "cellular_component": [ { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "M0RDY6", "url": "https://www.uniprot.org/uniprotkb/M0RDY6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M0RDY6-1" }, { "uniprot_canonical_ac": "F1M5H6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1M5H6", "url": "https://www.uniprot.org/uniprotkb/F1M5H6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1128, "chemical_mass": 125312.0, "gene_names": "Tp53bp2;Tp53bp2;Trp53bp2", "protein_name": "", "disease": [ { "disease_id": "DOID:0060412", "name": "chromosome 1q41-q42 deletion syndrome", "description": "A chromosomal deletion syndrome that has_material_basis_in deletion of the chromosome 1q41-q42 region.", "url": "https://disease-ontology.org/term/DOID:0060412", "evidence": [ { "id": "0060412", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060412" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1M5H6", "url": "https://www.uniprot.org/uniprotkb/F1M5H6" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1M5H6", "url": "https://www.uniprot.org/uniprotkb/F1M5H6" } ], "pmid": "" }, { "name": "cell junction", "id": "GO:0030054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030054", "evidence": [ { "database": "UniProtKB", "id": "F1M5H6", "url": "https://www.uniprot.org/uniprotkb/F1M5H6" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "F1M5H6", "url": "https://www.uniprot.org/uniprotkb/F1M5H6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1M5H6", "url": "https://www.uniprot.org/uniprotkb/F1M5H6" } ], "pmid": "" } ], "biological_process": [ { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "F1M5H6", "url": "https://www.uniprot.org/uniprotkb/F1M5H6" } ], "pmid": "" }, { "name": "regulation of apoptotic process", "id": "GO:0042981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042981", "evidence": [ { "database": "UniProtKB", "id": "F1M5H6", "url": "https://www.uniprot.org/uniprotkb/F1M5H6" } ], "pmid": "" }, { "name": "intrinsic apoptotic signaling pathway by p53 class mediator", "id": "GO:0072332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072332", "evidence": [ { "database": "UniProtKB", "id": "F1M5H6", "url": "https://www.uniprot.org/uniprotkb/F1M5H6" } ], "pmid": "" }, { "name": "positive regulation of execution phase of apoptosis", "id": "GO:1900119", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900119", "evidence": [ { "database": "UniProtKB", "id": "F1M5H6", "url": "https://www.uniprot.org/uniprotkb/F1M5H6" } ], "pmid": "" } ], "molecular_function": [ { "name": "p53 binding", "id": "GO:0002039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002039", "evidence": [ { "database": "UniProtKB", "id": "F1M5H6", "url": "https://www.uniprot.org/uniprotkb/F1M5H6" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "F1M5H6", "url": "https://www.uniprot.org/uniprotkb/F1M5H6" } ], "pmid": "" }, { "name": "NF-kappaB binding", "id": "GO:0051059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051059", "evidence": [ { "database": "UniProtKB", "id": "F1M5H6", "url": "https://www.uniprot.org/uniprotkb/F1M5H6" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "F1M5H6", "url": "https://www.uniprot.org/uniprotkb/F1M5H6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1M5H6-1" }, { "uniprot_canonical_ac": "M0RCP1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "M0RCP1", "url": "https://www.uniprot.org/uniprotkb/M0RCP1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1008, "chemical_mass": 113320.0, "gene_names": "Lilrb3;Lilrb3;RGD1566307", "protein_name": "", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "M0RCP1", "url": "https://www.uniprot.org/uniprotkb/M0RCP1" } ], "pmid": "" } ], "biological_process": [ { "name": "cell surface receptor signaling pathway", "id": "GO:0007166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007166", "evidence": [ { "database": "UniProtKB", "id": "M0RCP1", "url": "https://www.uniprot.org/uniprotkb/M0RCP1" } ], "pmid": "" }, { "name": "immune response-inhibiting cell surface receptor signaling pathway", "id": "GO:0002767", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002767", "evidence": [ { "database": "UniProtKB", "id": "M0RCP1", "url": "https://www.uniprot.org/uniprotkb/M0RCP1" } ], "pmid": "" }, { "name": "cytokine-mediated signaling pathway", "id": "GO:0019221", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019221", "evidence": [ { "database": "UniProtKB", "id": "M0RCP1", "url": "https://www.uniprot.org/uniprotkb/M0RCP1" } ], "pmid": "" } ], "molecular_function": [ { "name": "inhibitory MHC class I receptor activity", "id": "GO:0032396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032396", "evidence": [ { "database": "UniProtKB", "id": "M0RCP1", "url": "https://www.uniprot.org/uniprotkb/M0RCP1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M0RCP1-1" }, { "uniprot_canonical_ac": "F1LPI1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1LPI1", "url": "https://www.uniprot.org/uniprotkb/F1LPI1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1314, "chemical_mass": 151037.0, "gene_names": "Cspp1;Cspp1;RGD1307055", "protein_name": "", "disease": [ { "disease_id": "DOID:0110990", "name": "Joubert syndrome 21", "description": "A Joubert syndrome that has_material_basis_in homozygous or compound heterozygous mutation in the CSPP1 gene on chromosome 8q13.", "url": "https://disease-ontology.org/term/DOID:0110990", "evidence": [ { "id": "0110990", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110990" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "spindle pole", "id": "GO:0000922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000922", "evidence": [ { "database": "UniProtKB", "id": "F1LPI1", "url": "https://www.uniprot.org/uniprotkb/F1LPI1" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "F1LPI1", "url": "https://www.uniprot.org/uniprotkb/F1LPI1" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "F1LPI1", "url": "https://www.uniprot.org/uniprotkb/F1LPI1" } ], "pmid": "" }, { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "F1LPI1", "url": "https://www.uniprot.org/uniprotkb/F1LPI1" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "F1LPI1", "url": "https://www.uniprot.org/uniprotkb/F1LPI1" } ], "pmid": "" }, { "name": "centriolar satellite", "id": "GO:0034451", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034451", "evidence": [ { "database": "UniProtKB", "id": "F1LPI1", "url": "https://www.uniprot.org/uniprotkb/F1LPI1" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of cytokinesis", "id": "GO:0032467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032467", "evidence": [ { "database": "UniProtKB", "id": "F1LPI1", "url": "https://www.uniprot.org/uniprotkb/F1LPI1" } ], "pmid": "" }, { "name": "positive regulation of cell division", "id": "GO:0051781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051781", "evidence": [ { "database": "UniProtKB", "id": "F1LPI1", "url": "https://www.uniprot.org/uniprotkb/F1LPI1" } ], "pmid": "" } ], "molecular_function": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "F1LPI1", "url": "https://www.uniprot.org/uniprotkb/F1LPI1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1LPI1-1" }, { "uniprot_canonical_ac": "F6Q5G6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F6Q5G6", "url": "https://www.uniprot.org/uniprotkb/F6Q5G6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 510, "chemical_mass": 56203.0, "gene_names": "Aplf;Aplf;RGD1565557", "protein_name": "Aprataxin and PNK-like factor", "disease": [], "biological_process": [ { "name": "double-strand break repair", "id": "GO:0006302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006302", "evidence": [ { "database": "UniProtKB", "id": "F6Q5G6", "url": "https://www.uniprot.org/uniprotkb/F6Q5G6" } ], "pmid": "" }, { "name": "regulation of epithelial to mesenchymal transition", "id": "GO:0010717", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010717", "evidence": [ { "database": "UniProtKB", "id": "F6Q5G6", "url": "https://www.uniprot.org/uniprotkb/F6Q5G6" } ], "pmid": "" }, { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "F6Q5G6", "url": "https://www.uniprot.org/uniprotkb/F6Q5G6" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "F6Q5G6", "url": "https://www.uniprot.org/uniprotkb/F6Q5G6" } ], "pmid": "" }, { "name": "double-strand break repair via nonhomologous end joining", "id": "GO:0006303", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006303", "evidence": [ { "database": "UniProtKB", "id": "F6Q5G6", "url": "https://www.uniprot.org/uniprotkb/F6Q5G6" } ], "pmid": "" }, { "name": "single strand break repair", "id": "GO:0000012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000012", "evidence": [ { "database": "UniProtKB", "id": "F6Q5G6", "url": "https://www.uniprot.org/uniprotkb/F6Q5G6" } ], "pmid": "" }, { "name": "regulation of isotype switching", "id": "GO:0045191", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045191", "evidence": [ { "database": "UniProtKB", "id": "F6Q5G6", "url": "https://www.uniprot.org/uniprotkb/F6Q5G6" } ], "pmid": "" }, { "name": "embryo implantation", "id": "GO:0007566", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007566", "evidence": [ { "database": "UniProtKB", "id": "F6Q5G6", "url": "https://www.uniprot.org/uniprotkb/F6Q5G6" } ], "pmid": "" }, { "name": "protein localization to chromatin", "id": "GO:0071168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071168", "evidence": [ { "database": "UniProtKB", "id": "F6Q5G6", "url": "https://www.uniprot.org/uniprotkb/F6Q5G6" } ], "pmid": "" }, { "name": "DNA repair-dependent chromatin remodeling", "id": "GO:0140861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140861", "evidence": [ { "database": "UniProtKB", "id": "F6Q5G6", "url": "https://www.uniprot.org/uniprotkb/F6Q5G6" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA-(apurinic or apyrimidinic site) endonuclease activity", "id": "GO:0003906", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003906", "evidence": [ { "database": "UniProtKB", "id": "F6Q5G6", "url": "https://www.uniprot.org/uniprotkb/F6Q5G6" } ], "pmid": "" }, { "name": "3'-5' exonuclease activity", "id": "GO:0008408", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008408", "evidence": [ { "database": "UniProtKB", "id": "F6Q5G6", "url": "https://www.uniprot.org/uniprotkb/F6Q5G6" } ], "pmid": "" }, { "name": "poly-ADP-D-ribose binding", "id": "GO:0072572", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072572", "evidence": [ { "database": "UniProtKB", "id": "F6Q5G6", "url": "https://www.uniprot.org/uniprotkb/F6Q5G6" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F6Q5G6", "url": "https://www.uniprot.org/uniprotkb/F6Q5G6" } ], "pmid": "" }, { "name": "nucleotide binding", "id": "GO:0000166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000166", "evidence": [ { "database": "UniProtKB", "id": "F6Q5G6", "url": "https://www.uniprot.org/uniprotkb/F6Q5G6" } ], "pmid": "" }, { "name": "DNA endonuclease activity", "id": "GO:0004520", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004520", "evidence": [ { "database": "UniProtKB", "id": "F6Q5G6", "url": "https://www.uniprot.org/uniprotkb/F6Q5G6" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "F6Q5G6", "url": "https://www.uniprot.org/uniprotkb/F6Q5G6" } ], "pmid": "" }, { "name": "protein folding chaperone", "id": "GO:0044183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044183", "evidence": [ { "database": "UniProtKB", "id": "F6Q5G6", "url": "https://www.uniprot.org/uniprotkb/F6Q5G6" } ], "pmid": "" }, { "name": "ADP-D-ribose modification-dependent protein binding", "id": "GO:0160002", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160002", "evidence": [ { "database": "UniProtKB", "id": "F6Q5G6", "url": "https://www.uniprot.org/uniprotkb/F6Q5G6" } ], "pmid": "" }, { "name": "histone chaperone activity", "id": "GO:0140713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140713", "evidence": [ { "database": "UniProtKB", "id": "F6Q5G6", "url": "https://www.uniprot.org/uniprotkb/F6Q5G6" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F6Q5G6", "url": "https://www.uniprot.org/uniprotkb/F6Q5G6" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F6Q5G6", "url": "https://www.uniprot.org/uniprotkb/F6Q5G6" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F6Q5G6", "url": "https://www.uniprot.org/uniprotkb/F6Q5G6" } ], "pmid": "" }, { "name": "site of double-strand break", "id": "GO:0035861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035861", "evidence": [ { "database": "UniProtKB", "id": "F6Q5G6", "url": "https://www.uniprot.org/uniprotkb/F6Q5G6" } ], "pmid": "" }, { "name": "site of DNA damage", "id": "GO:0090734", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090734", "evidence": [ { "database": "UniProtKB", "id": "F6Q5G6", "url": "https://www.uniprot.org/uniprotkb/F6Q5G6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F6Q5G6-1" }, { "uniprot_canonical_ac": "F7FKH2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F7FKH2", "url": "https://www.uniprot.org/uniprotkb/F7FKH2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 658, "chemical_mass": 76865.0, "gene_names": "Zmynd11;BS69;Zmynd11", "protein_name": "Zinc finger MYND domain-containing protein 11", "disease": [ { "disease_id": "DOID:0070060", "name": "autosomal dominant intellectual developmental disorder 30", "description": "An autosomal dominant intellectual developmental disorder that has_material_basis_in an autosomal dominant mutation of the ZMYND11 gene on chromosome 10p15.3.", "url": "https://disease-ontology.org/term/DOID:0070060", "evidence": [ { "id": "0070060", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070060" } ], "weight": 0.0 }, { "disease_id": "DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ], "weight": 0.0 } ], "biological_process": [ { "name": "regulation of transcription elongation by RNA polymerase II", "id": "GO:0034243", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034243", "evidence": [ { "database": "UniProtKB", "id": "F7FKH2", "url": "https://www.uniprot.org/uniprotkb/F7FKH2" } ], "pmid": "" }, { "name": "defense response to virus", "id": "GO:0051607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051607", "evidence": [ { "database": "UniProtKB", "id": "F7FKH2", "url": "https://www.uniprot.org/uniprotkb/F7FKH2" } ], "pmid": "" }, { "name": "negative regulation of canonical NF-kappaB signal transduction", "id": "GO:0043124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043124", "evidence": [ { "database": "UniProtKB", "id": "F7FKH2", "url": "https://www.uniprot.org/uniprotkb/F7FKH2" } ], "pmid": "" }, { "name": "regulation of signal transduction", "id": "GO:0009966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009966", "evidence": [ { "database": "UniProtKB", "id": "F7FKH2", "url": "https://www.uniprot.org/uniprotkb/F7FKH2" } ], "pmid": "" }, { "name": "negative regulation of extrinsic apoptotic signaling pathway", "id": "GO:2001237", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001237", "evidence": [ { "database": "UniProtKB", "id": "F7FKH2", "url": "https://www.uniprot.org/uniprotkb/F7FKH2" } ], "pmid": "" }, { "name": "negative regulation of JNK cascade", "id": "GO:0046329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046329", "evidence": [ { "database": "UniProtKB", "id": "F7FKH2", "url": "https://www.uniprot.org/uniprotkb/F7FKH2" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F7FKH2", "url": "https://www.uniprot.org/uniprotkb/F7FKH2" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "F7FKH2", "url": "https://www.uniprot.org/uniprotkb/F7FKH2" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F7FKH2", "url": "https://www.uniprot.org/uniprotkb/F7FKH2" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F7FKH2", "url": "https://www.uniprot.org/uniprotkb/F7FKH2" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "F7FKH2", "url": "https://www.uniprot.org/uniprotkb/F7FKH2" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F7FKH2", "url": "https://www.uniprot.org/uniprotkb/F7FKH2" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "F7FKH2", "url": "https://www.uniprot.org/uniprotkb/F7FKH2" } ], "pmid": "" }, { "name": "double-stranded DNA binding", "id": "GO:0003690", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003690", "evidence": [ { "database": "UniProtKB", "id": "F7FKH2", "url": "https://www.uniprot.org/uniprotkb/F7FKH2" } ], "pmid": "" }, { "name": "histone H3K36me3 reader activity", "id": "GO:0140003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140003", "evidence": [ { "database": "UniProtKB", "id": "F7FKH2", "url": "https://www.uniprot.org/uniprotkb/F7FKH2" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "F7FKH2", "url": "https://www.uniprot.org/uniprotkb/F7FKH2" } ], "pmid": "" }, { "name": "histone H3 reader activity", "id": "GO:0140006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140006", "evidence": [ { "database": "UniProtKB", "id": "F7FKH2", "url": "https://www.uniprot.org/uniprotkb/F7FKH2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F7FKH2-1" }, { "uniprot_canonical_ac": "A0A8I6A7X8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A7X8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A7X8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 451, "chemical_mass": 50176.0, "gene_names": "Pphln1", "protein_name": "", "disease": [], "biological_process": [ { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A7X8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A7X8" } ], "pmid": "" }, { "name": "negative regulation of gene expression, epigenetic", "id": "GO:0045814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045814", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A7X8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A7X8" } ], "pmid": "" }, { "name": "protein localization to heterochromatin", "id": "GO:0097355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097355", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A7X8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A7X8" } ], "pmid": "" }, { "name": "negative regulation of type I interferon production", "id": "GO:0032480", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032480", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A7X8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A7X8" } ], "pmid": "" }, { "name": "constitutive heterochromatin formation", "id": "GO:0140719", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140719", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A7X8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A7X8" } ], "pmid": "" }, { "name": "transposable element silencing by heterochromatin formation", "id": "GO:0141005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141005", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A7X8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A7X8" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A7X8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A7X8" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A7X8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A7X8" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A7X8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A7X8" } ], "pmid": "" }, { "name": "heterochromatin", "id": "GO:0000792", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000792", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A7X8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A7X8" } ], "pmid": "" }, { "name": "HUSH2 complex", "id": "GO:0140286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140286", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A7X8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A7X8" } ], "pmid": "" }, { "name": "HUSH complex", "id": "GO:0140283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140283", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A7X8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A7X8" } ], "pmid": "" } ], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A7X8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A7X8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6A7X8-1" }, { "uniprot_canonical_ac": "F1LND0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1LND0", "url": "https://www.uniprot.org/uniprotkb/F1LND0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1608, "chemical_mass": 158173.0, "gene_names": "Col16a1", "protein_name": "Collagen alpha-1(XVI) chain", "disease": [ { "disease_id": "DOID:12930", "name": "dilated cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by an an enlarged heart and damage to the myocardium causing the heart to pump blood inefficiently.", "url": "https://disease-ontology.org/term/DOID:12930", "evidence": [ { "id": "12930", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12930" } ], "weight": 0.0 } ], "biological_process": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "F1LND0", "url": "https://www.uniprot.org/uniprotkb/F1LND0" } ], "pmid": "" }, { "name": "cell adhesion mediated by integrin", "id": "GO:0033627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033627", "evidence": [ { "database": "UniProtKB", "id": "F1LND0", "url": "https://www.uniprot.org/uniprotkb/F1LND0" } ], "pmid": "" }, { "name": "positive regulation of focal adhesion assembly", "id": "GO:0051894", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051894", "evidence": [ { "database": "UniProtKB", "id": "F1LND0", "url": "https://www.uniprot.org/uniprotkb/F1LND0" } ], "pmid": "" }, { "name": "cellular response to amino acid stimulus", "id": "GO:0071230", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071230", "evidence": [ { "database": "UniProtKB", "id": "F1LND0", "url": "https://www.uniprot.org/uniprotkb/F1LND0" } ], "pmid": "" }, { "name": "integrin activation", "id": "GO:0033622", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033622", "evidence": [ { "database": "UniProtKB", "id": "F1LND0", "url": "https://www.uniprot.org/uniprotkb/F1LND0" } ], "pmid": "" } ], "molecular_function": [ { "name": "integrin binding", "id": "GO:0005178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005178", "evidence": [ { "database": "UniProtKB", "id": "F1LND0", "url": "https://www.uniprot.org/uniprotkb/F1LND0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "F1LND0-1", "start_pos": "1337", "end_pos": "1337", "site_lbl": "Thr1337", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1337, "start_aa": "Thr", "end_pos": 1337, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1337", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "F1LND0-1", "start_pos": "466", "end_pos": "466", "site_lbl": "Thr466", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" }, { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "reported site T465 is on non-canonical isoform A0A8I5Y198-1 which maps to canonical isoform site F1LND0-1:466", "icn3d_view": {}, "start_pos": 466, "start_aa": "Thr", "end_pos": 466, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr466", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "F1LND0-1", "start_pos": "714", "end_pos": "714", "site_lbl": "Thr714", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" }, { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "reported site T713 is on non-canonical isoform A0A8I5Y198-1 which maps to canonical isoform site F1LND0-1:714", "icn3d_view": {}, "start_pos": 714, "start_aa": "Thr", "end_pos": 714, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr714", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "F1LND0-1", "start_pos": "817", "end_pos": "817", "site_lbl": "Thr817", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" }, { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "reported site T816 is on non-canonical isoform A0A8I5Y198-1 which maps to canonical isoform site F1LND0-1:817", "icn3d_view": {}, "start_pos": 817, "start_aa": "Thr", "end_pos": 817, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr817", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "F1LND0-1" }, { "uniprot_canonical_ac": "F1LXS3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1LXS3", "url": "https://www.uniprot.org/uniprotkb/F1LXS3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 912, "chemical_mass": 101643.0, "gene_names": "Matn2", "protein_name": "Matrilin-2", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "F1LXS3", "url": "https://www.uniprot.org/uniprotkb/F1LXS3" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "F1LXS3", "url": "https://www.uniprot.org/uniprotkb/F1LXS3" } ], "pmid": "" }, { "name": "basement membrane", "id": "GO:0005604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005604", "evidence": [ { "database": "UniProtKB", "id": "F1LXS3", "url": "https://www.uniprot.org/uniprotkb/F1LXS3" } ], "pmid": "" }, { "name": "matrilin complex", "id": "GO:0120216", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120216", "evidence": [ { "database": "UniProtKB", "id": "F1LXS3", "url": "https://www.uniprot.org/uniprotkb/F1LXS3" } ], "pmid": "" } ], "molecular_function": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "F1LXS3", "url": "https://www.uniprot.org/uniprotkb/F1LXS3" } ], "pmid": "" } ], "biological_process": [ { "name": "neuron projection development", "id": "GO:0031175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031175", "evidence": [ { "database": "UniProtKB", "id": "F1LXS3", "url": "https://www.uniprot.org/uniprotkb/F1LXS3" } ], "pmid": "" }, { "name": "neuron migration", "id": "GO:0001764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001764", "evidence": [ { "database": "UniProtKB", "id": "F1LXS3", "url": "https://www.uniprot.org/uniprotkb/F1LXS3" } ], "pmid": "" }, { "name": "response to axon injury", "id": "GO:0048678", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048678", "evidence": [ { "database": "UniProtKB", "id": "F1LXS3", "url": "https://www.uniprot.org/uniprotkb/F1LXS3" } ], "pmid": "" }, { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "F1LXS3", "url": "https://www.uniprot.org/uniprotkb/F1LXS3" } ], "pmid": "" }, { "name": "glial cell migration", "id": "GO:0008347", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008347", "evidence": [ { "database": "UniProtKB", "id": "F1LXS3", "url": "https://www.uniprot.org/uniprotkb/F1LXS3" } ], "pmid": "" }, { "name": "dendrite regeneration", "id": "GO:0031104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031104", "evidence": [ { "database": "UniProtKB", "id": "F1LXS3", "url": "https://www.uniprot.org/uniprotkb/F1LXS3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1LXS3-1" }, { "uniprot_canonical_ac": "A0A8I5ZYZ8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYZ8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 369, "chemical_mass": 40548.0, "gene_names": "Chmp2a;Ube2m;Chmp2a;Ube2m", "protein_name": "NEDD8-conjugating enzyme UBC12", "disease": [], "cellular_component": [ { "name": "ESCRT III complex", "id": "GO:0000815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000815", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYZ8" } ], "pmid": "" }, { "name": "kinetochore microtubule", "id": "GO:0005828", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005828", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYZ8" } ], "pmid": "" }, { "name": "autophagosome membrane", "id": "GO:0000421", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000421", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYZ8" } ], "pmid": "" }, { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYZ8" } ], "pmid": "" }, { "name": "nuclear pore", "id": "GO:0005643", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005643", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYZ8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYZ8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYZ8" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYZ8" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYZ8" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYZ8" } ], "pmid": "" }, { "name": "midbody", "id": "GO:0030496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030496", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYZ8" } ], "pmid": "" }, { "name": "membrane coat", "id": "GO:0030117", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030117", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYZ8" } ], "pmid": "" }, { "name": "multivesicular body membrane", "id": "GO:0032585", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032585", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYZ8" } ], "pmid": "" }, { "name": "amphisome membrane", "id": "GO:1904930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904930", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYZ8" } ], "pmid": "" }, { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYZ8" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYZ8" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYZ8" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYZ8" } ], "pmid": "" }, { "name": "postsynapse", "id": "GO:0098794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098794", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYZ8" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYZ8" } ], "pmid": "" }, { "name": "presynapse", "id": "GO:0098793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098793", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYZ8" } ], "pmid": "" } ], "biological_process": [ { "name": "plasma membrane repair", "id": "GO:0001778", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001778", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYZ8" } ], "pmid": "" }, { "name": "membrane invagination", "id": "GO:0010324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010324", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYZ8" } ], "pmid": "" }, { "name": "regulation of centrosome duplication", "id": "GO:0010824", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010824", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYZ8" } ], "pmid": "" }, { "name": "nuclear membrane reassembly", "id": "GO:0031468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031468", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYZ8" } ], "pmid": "" }, { "name": "viral budding via host ESCRT complex", "id": "GO:0039702", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0039702", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYZ8" } ], "pmid": "" }, { "name": "multivesicular body sorting pathway", "id": "GO:0071985", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071985", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYZ8" } ], "pmid": "" }, { "name": "autophagosome maturation", "id": "GO:0097352", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097352", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYZ8" } ], "pmid": "" }, { "name": "protein homooligomerization", "id": "GO:0051260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051260", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYZ8" } ], "pmid": "" }, { "name": "autophagy", "id": "GO:0006914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006914", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYZ8" } ], "pmid": "" }, { "name": "establishment of protein localization", "id": "GO:0045184", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045184", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYZ8" } ], "pmid": "" }, { "name": "exit from mitosis", "id": "GO:0010458", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010458", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYZ8" } ], "pmid": "" }, { "name": "mitotic metaphase chromosome alignment", "id": "GO:0007080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007080", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYZ8" } ], "pmid": "" }, { "name": "protein polymerization", "id": "GO:0051258", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051258", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYZ8" } ], "pmid": "" }, { "name": "positive regulation of exosomal secretion", "id": "GO:1903543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903543", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYZ8" } ], "pmid": "" }, { "name": "negative regulation of centriole elongation", "id": "GO:1903723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903723", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYZ8" } ], "pmid": "" }, { "name": "late endosome to lysosome transport", "id": "GO:1902774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902774", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYZ8" } ], "pmid": "" }, { "name": "regulation of mitotic spindle assembly", "id": "GO:1901673", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901673", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYZ8" } ], "pmid": "" }, { "name": "nucleus organization", "id": "GO:0006997", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006997", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYZ8" } ], "pmid": "" }, { "name": "membrane fission", "id": "GO:0090148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090148", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYZ8" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway", "id": "GO:0043162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043162", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYZ8" } ], "pmid": "" }, { "name": "viral budding from plasma membrane", "id": "GO:0046761", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046761", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYZ8" } ], "pmid": "" }, { "name": "midbody abscission", "id": "GO:0061952", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061952", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYZ8" } ], "pmid": "" }, { "name": "positive regulation of neuron apoptotic process", "id": "GO:0043525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043525", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYZ8" } ], "pmid": "" }, { "name": "protein neddylation", "id": "GO:0045116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045116", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYZ8" } ], "pmid": "" }, { "name": "regulation of postsynapse assembly", "id": "GO:0150052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0150052", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYZ8" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein domain specific binding", "id": "GO:0019904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019904", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYZ8" } ], "pmid": "" }, { "name": "phosphatidylcholine binding", "id": "GO:0031210", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031210", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYZ8" } ], "pmid": "" }, { "name": "membrane bending activity", "id": "GO:0180020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0180020", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYZ8" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYZ8" } ], "pmid": "" }, { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYZ8" } ], "pmid": "" }, { "name": "NEDD8 transferase activity", "id": "GO:0019788", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019788", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYZ8" } ], "pmid": "" }, { "name": "transferase activity", "id": "GO:0016740", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016740", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYZ8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZYZ8-1" }, { "uniprot_canonical_ac": "F1LTS3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1LTS3", "url": "https://www.uniprot.org/uniprotkb/F1LTS3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 651, "chemical_mass": 73206.0, "gene_names": "Redic1;C7h12orf40;LOC690142;Redic1", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1LTS3-1" }, { "uniprot_canonical_ac": "F1M9J2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1M9J2", "url": "https://www.uniprot.org/uniprotkb/F1M9J2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 556, "chemical_mass": 63463.0, "gene_names": "Zfp870;Zfp709l2;Zfp870", "protein_name": "", "disease": [], "biological_process": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "F1M9J2", "url": "https://www.uniprot.org/uniprotkb/F1M9J2" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1M9J2", "url": "https://www.uniprot.org/uniprotkb/F1M9J2" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "F1M9J2", "url": "https://www.uniprot.org/uniprotkb/F1M9J2" } ], "pmid": "" }, { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "F1M9J2", "url": "https://www.uniprot.org/uniprotkb/F1M9J2" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1M9J2", "url": "https://www.uniprot.org/uniprotkb/F1M9J2" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1M9J2", "url": "https://www.uniprot.org/uniprotkb/F1M9J2" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "F1M9J2", "url": "https://www.uniprot.org/uniprotkb/F1M9J2" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "F1M9J2", "url": "https://www.uniprot.org/uniprotkb/F1M9J2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1M9J2-1" }, { "uniprot_canonical_ac": "F1LRT4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1LRT4", "url": "https://www.uniprot.org/uniprotkb/F1LRT4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 508, "chemical_mass": 57323.0, "gene_names": "Ccdc125;Ccdc125;RGD1561673", "protein_name": "", "disease": [], "biological_process": [ { "name": "regulation of cell motility", "id": "GO:2000145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000145", "evidence": [ { "database": "UniProtKB", "id": "F1LRT4", "url": "https://www.uniprot.org/uniprotkb/F1LRT4" } ], "pmid": "" }, { "name": "activation of GTPase activity", "id": "GO:0090630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090630", "evidence": [ { "database": "UniProtKB", "id": "F1LRT4", "url": "https://www.uniprot.org/uniprotkb/F1LRT4" } ], "pmid": "" }, { "name": "negative regulation of Rho protein signal transduction", "id": "GO:0035024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035024", "evidence": [ { "database": "UniProtKB", "id": "F1LRT4", "url": "https://www.uniprot.org/uniprotkb/F1LRT4" } ], "pmid": "" }, { "name": "negative regulation of cell motility", "id": "GO:2000146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000146", "evidence": [ { "database": "UniProtKB", "id": "F1LRT4", "url": "https://www.uniprot.org/uniprotkb/F1LRT4" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1LRT4", "url": "https://www.uniprot.org/uniprotkb/F1LRT4" } ], "pmid": "" } ], "molecular_function": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "F1LRT4", "url": "https://www.uniprot.org/uniprotkb/F1LRT4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1LRT4-1" }, { "uniprot_canonical_ac": "F1M1X7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1M1X7", "url": "https://www.uniprot.org/uniprotkb/F1M1X7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 614, "chemical_mass": 67577.0, "gene_names": "Ankrd55;Ankrd55;RGD1307735", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1M1X7-1" }, { "uniprot_canonical_ac": "F1MAL0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1MAL0", "url": "https://www.uniprot.org/uniprotkb/F1MAL0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 604, "chemical_mass": 68380.0, "gene_names": "Zfp266;Zfp266;Zfp426l;Zfp426;Znf266", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1MAL0", "url": "https://www.uniprot.org/uniprotkb/F1MAL0" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1MAL0", "url": "https://www.uniprot.org/uniprotkb/F1MAL0" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "F1MAL0", "url": "https://www.uniprot.org/uniprotkb/F1MAL0" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1MAL0", "url": "https://www.uniprot.org/uniprotkb/F1MAL0" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "F1MAL0", "url": "https://www.uniprot.org/uniprotkb/F1MAL0" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "F1MAL0", "url": "https://www.uniprot.org/uniprotkb/F1MAL0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1MAL0-1" }, { "uniprot_canonical_ac": "M0RAV7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "M0RAV7", "url": "https://www.uniprot.org/uniprotkb/M0RAV7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 871, "chemical_mass": 96127.0, "gene_names": "Adgrd1;Adgrd1;Gpr133", "protein_name": "Adhesion G-protein coupled receptor D1", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "M0RAV7", "url": "https://www.uniprot.org/uniprotkb/M0RAV7" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "M0RAV7", "url": "https://www.uniprot.org/uniprotkb/M0RAV7" } ], "pmid": "" } ], "biological_process": [ { "name": "cell surface receptor signaling pathway", "id": "GO:0007166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007166", "evidence": [ { "database": "UniProtKB", "id": "M0RAV7", "url": "https://www.uniprot.org/uniprotkb/M0RAV7" } ], "pmid": "" }, { "name": "adenylate cyclase-activating G protein-coupled receptor signaling pathway", "id": "GO:0007189", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007189", "evidence": [ { "database": "UniProtKB", "id": "M0RAV7", "url": "https://www.uniprot.org/uniprotkb/M0RAV7" } ], "pmid": "" }, { "name": "regulation of skeletal muscle contraction", "id": "GO:0014819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014819", "evidence": [ { "database": "UniProtKB", "id": "M0RAV7", "url": "https://www.uniprot.org/uniprotkb/M0RAV7" } ], "pmid": "" }, { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "M0RAV7", "url": "https://www.uniprot.org/uniprotkb/M0RAV7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M0RAV7-1", "start_pos": "270", "end_pos": "270", "site_lbl": "Thr270", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 270, "start_aa": "Thr", "end_pos": 270, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr270", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "M0RAV7-1" }, { "uniprot_canonical_ac": "A0A8I5ZJ62-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZJ62", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZJ62" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 154, "chemical_mass": 17076.0, "gene_names": "Glipr2;Glipr2", "protein_name": "Golgi-associated plant pathogenesis-related protein 1", "disease": [ { "disease_id": "DOID:3498", "name": "pancreatic ductal adenocarcinoma", "description": "A pancreatic adenocarcinoma that derives_from pancreatic duct cells.", "url": "https://disease-ontology.org/term/DOID:3498", "evidence": [ { "id": "3498", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3498" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZJ62", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZJ62" } ], "pmid": "" }, { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZJ62", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZJ62" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZJ62", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZJ62" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZJ62", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZJ62" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of ERK1 and ERK2 cascade", "id": "GO:0070374", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070374", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZJ62", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZJ62" } ], "pmid": "" }, { "name": "positive regulation of epithelial to mesenchymal transition", "id": "GO:0010718", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010718", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZJ62", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZJ62" } ], "pmid": "" }, { "name": "positive regulation of epithelial cell migration", "id": "GO:0010634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZJ62", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZJ62" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZJ62-1" }, { "uniprot_canonical_ac": "F1LX47-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1LX47", "url": "https://www.uniprot.org/uniprotkb/F1LX47" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 836, "chemical_mass": 97429.0, "gene_names": "Drc11;Drc11;Iqca1;Iqca;RGD1305311", "protein_name": "", "disease": [], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1LX47", "url": "https://www.uniprot.org/uniprotkb/F1LX47" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "F1LX47", "url": "https://www.uniprot.org/uniprotkb/F1LX47" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1LX47-1" }, { "uniprot_canonical_ac": "G3V9Z0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "G3V9Z0", "url": "https://www.uniprot.org/uniprotkb/G3V9Z0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 341, "chemical_mass": 37777.0, "gene_names": "Or10al27;Or10al4c;Olr1696;Olr1701;Or10al5b;Or10al6-ps1;Or10al6;Or10al7", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "G3V9Z0", "url": "https://www.uniprot.org/uniprotkb/G3V9Z0" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "G3V9Z0", "url": "https://www.uniprot.org/uniprotkb/G3V9Z0" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G3V9Z0", "url": "https://www.uniprot.org/uniprotkb/G3V9Z0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "G3V9Z0-1" }, { "uniprot_canonical_ac": "A0A8I5ZUI6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUI6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUI6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 245, "chemical_mass": 27841.0, "gene_names": "Ssmem1;RGD1559502;Ssmem1", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZUI6-1" }, { "uniprot_canonical_ac": "A0A8I5ZUR6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUR6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUR6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 413, "chemical_mass": 47001.0, "gene_names": "Ccdc34", "protein_name": "", "disease": [ { "disease_id": "DOID:0070575", "name": "spermatogenic failure 76", "description": "A spermatogenic failure characterized by oligoasthenoteratozoospermia that has_material_basis_in homozygous mutation in the CCDC34 gene on chromosome 11p14.1.", "url": "https://disease-ontology.org/term/DOID:0070575", "evidence": [ { "id": "0070575", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070575" } ], "weight": 0.0 }, { "disease_id": "DOID:0111910", "name": "spermatogenic failure", "description": "A male infertility characterized by disruption of the process of sperm development from diploid cells into mature haploid spermatozoa.", "url": "https://disease-ontology.org/term/DOID:0111910", "evidence": [ { "id": "0111910", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111910" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "sperm end piece", "id": "GO:0097229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097229", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUR6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUR6" } ], "pmid": "" }, { "name": "sperm principal piece", "id": "GO:0097228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097228", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUR6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUR6" } ], "pmid": "" }, { "name": "sperm midpiece", "id": "GO:0097225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097225", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUR6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUR6" } ], "pmid": "" }, { "name": "sperm head-tail coupling apparatus", "id": "GO:0120212", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120212", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUR6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUR6" } ], "pmid": "" } ], "biological_process": [ { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUR6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUR6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZUR6-1" }, { "uniprot_canonical_ac": "F1LX85-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1LX85", "url": "https://www.uniprot.org/uniprotkb/F1LX85" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1645, "chemical_mass": 183291.0, "gene_names": "Katnip;LOC361646", "protein_name": "", "disease": [ { "disease_id": "DOID:0110995", "name": "Joubert syndrome 26", "description": "A Joubert syndrome characterized by global developmental delay and cerebellar hypoplasia that has_material_basis_in homozygous mutation in the KIAA0556 gene on chromosome 16p12.", "url": "https://disease-ontology.org/term/DOID:0110995", "evidence": [ { "id": "0110995", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110995" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "F1LX85", "url": "https://www.uniprot.org/uniprotkb/F1LX85" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "F1LX85", "url": "https://www.uniprot.org/uniprotkb/F1LX85" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "F1LX85", "url": "https://www.uniprot.org/uniprotkb/F1LX85" } ], "pmid": "" }, { "name": "ciliary base", "id": "GO:0097546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097546", "evidence": [ { "database": "UniProtKB", "id": "F1LX85", "url": "https://www.uniprot.org/uniprotkb/F1LX85" } ], "pmid": "" }, { "name": "9+2 motile cilium", "id": "GO:0097729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097729", "evidence": [ { "database": "UniProtKB", "id": "F1LX85", "url": "https://www.uniprot.org/uniprotkb/F1LX85" } ], "pmid": "" } ], "molecular_function": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "F1LX85", "url": "https://www.uniprot.org/uniprotkb/F1LX85" } ], "pmid": "" }, { "name": "tubulin binding", "id": "GO:0015631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015631", "evidence": [ { "database": "UniProtKB", "id": "F1LX85", "url": "https://www.uniprot.org/uniprotkb/F1LX85" } ], "pmid": "" }, { "name": "intraciliary transport particle B binding", "id": "GO:0120170", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120170", "evidence": [ { "database": "UniProtKB", "id": "F1LX85", "url": "https://www.uniprot.org/uniprotkb/F1LX85" } ], "pmid": "" } ], "biological_process": [ { "name": "cerebrospinal fluid circulation", "id": "GO:0090660", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090660", "evidence": [ { "database": "UniProtKB", "id": "F1LX85", "url": "https://www.uniprot.org/uniprotkb/F1LX85" } ], "pmid": "" }, { "name": "negative regulation of motile cilium assembly", "id": "GO:1905504", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905504", "evidence": [ { "database": "UniProtKB", "id": "F1LX85", "url": "https://www.uniprot.org/uniprotkb/F1LX85" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1LX85-1" }, { "uniprot_canonical_ac": "F1LVL6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1LVL6", "url": "https://www.uniprot.org/uniprotkb/F1LVL6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 606, "chemical_mass": 65631.0, "gene_names": "Crtc3;Crtc3;RGD1309666", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1LVL6", "url": "https://www.uniprot.org/uniprotkb/F1LVL6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1LVL6", "url": "https://www.uniprot.org/uniprotkb/F1LVL6" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1LVL6", "url": "https://www.uniprot.org/uniprotkb/F1LVL6" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1LVL6", "url": "https://www.uniprot.org/uniprotkb/F1LVL6" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1LVL6", "url": "https://www.uniprot.org/uniprotkb/F1LVL6" } ], "pmid": "" }, { "name": "protein homotetramerization", "id": "GO:0051289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051289", "evidence": [ { "database": "UniProtKB", "id": "F1LVL6", "url": "https://www.uniprot.org/uniprotkb/F1LVL6" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "F1LVL6", "url": "https://www.uniprot.org/uniprotkb/F1LVL6" } ], "pmid": "" }, { "name": "cellular response to cAMP", "id": "GO:0071320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071320", "evidence": [ { "database": "UniProtKB", "id": "F1LVL6", "url": "https://www.uniprot.org/uniprotkb/F1LVL6" } ], "pmid": "" }, { "name": "negative regulation of lipid catabolic process", "id": "GO:0050995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050995", "evidence": [ { "database": "UniProtKB", "id": "F1LVL6", "url": "https://www.uniprot.org/uniprotkb/F1LVL6" } ], "pmid": "" }, { "name": "energy homeostasis", "id": "GO:0097009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097009", "evidence": [ { "database": "UniProtKB", "id": "F1LVL6", "url": "https://www.uniprot.org/uniprotkb/F1LVL6" } ], "pmid": "" }, { "name": "negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway", "id": "GO:0071878", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071878", "evidence": [ { "database": "UniProtKB", "id": "F1LVL6", "url": "https://www.uniprot.org/uniprotkb/F1LVL6" } ], "pmid": "" }, { "name": "macrophage activation", "id": "GO:0042116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042116", "evidence": [ { "database": "UniProtKB", "id": "F1LVL6", "url": "https://www.uniprot.org/uniprotkb/F1LVL6" } ], "pmid": "" } ], "molecular_function": [ { "name": "cAMP response element binding protein binding", "id": "GO:0008140", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008140", "evidence": [ { "database": "UniProtKB", "id": "F1LVL6", "url": "https://www.uniprot.org/uniprotkb/F1LVL6" } ], "pmid": "" }, { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "F1LVL6", "url": "https://www.uniprot.org/uniprotkb/F1LVL6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "F1LVL6-1", "start_pos": "437", "end_pos": "437", "site_lbl": "Thr437", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 437, "start_aa": "Thr", "end_pos": 437, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr437", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "F1LVL6-1" }, { "uniprot_canonical_ac": "A0A8I5ZRK9-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZRK9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZRK9" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 823, "chemical_mass": 87701.0, "gene_names": "Scarf1;Scarf1", "protein_name": "", "disease": [], "molecular_function": [ { "name": "scavenger receptor activity", "id": "GO:0005044", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005044", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZRK9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZRK9" } ], "pmid": "" }, { "name": "low-density lipoprotein particle binding", "id": "GO:0030169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030169", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZRK9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZRK9" } ], "pmid": "" } ], "biological_process": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZRK9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZRK9" } ], "pmid": "" }, { "name": "positive regulation of axon regeneration", "id": "GO:0048680", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048680", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZRK9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZRK9" } ], "pmid": "" }, { "name": "positive regulation of neuron projection development", "id": "GO:0010976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010976", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZRK9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZRK9" } ], "pmid": "" }, { "name": "neuron remodeling", "id": "GO:0016322", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016322", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZRK9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZRK9" } ], "pmid": "" }, { "name": "dendrite development", "id": "GO:0016358", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016358", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZRK9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZRK9" } ], "pmid": "" }, { "name": "heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules", "id": "GO:0007157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007157", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZRK9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZRK9" } ], "pmid": "" } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZRK9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZRK9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZRK9-1" }, { "uniprot_canonical_ac": "F1LWT0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1LWT0", "url": "https://www.uniprot.org/uniprotkb/F1LWT0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1266, "chemical_mass": 136789.0, "gene_names": "Simc1;LOC100361684;Pleiad", "protein_name": "SUMO-interacting motif-containing protein 1", "disease": [], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1LWT0", "url": "https://www.uniprot.org/uniprotkb/F1LWT0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1LWT0", "url": "https://www.uniprot.org/uniprotkb/F1LWT0" } ], "pmid": "" }, { "name": "sarcomere", "id": "GO:0030017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030017", "evidence": [ { "database": "UniProtKB", "id": "F1LWT0", "url": "https://www.uniprot.org/uniprotkb/F1LWT0" } ], "pmid": "" }, { "name": "PML body", "id": "GO:0016605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016605", "evidence": [ { "database": "UniProtKB", "id": "F1LWT0", "url": "https://www.uniprot.org/uniprotkb/F1LWT0" } ], "pmid": "" } ], "molecular_function": [ { "name": "peptidase inhibitor activity", "id": "GO:0030414", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030414", "evidence": [ { "database": "UniProtKB", "id": "F1LWT0", "url": "https://www.uniprot.org/uniprotkb/F1LWT0" } ], "pmid": "" }, { "name": "SUMO polymer binding", "id": "GO:0032184", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032184", "evidence": [ { "database": "UniProtKB", "id": "F1LWT0", "url": "https://www.uniprot.org/uniprotkb/F1LWT0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "F1LWT0-1", "start_pos": "649", "end_pos": "649", "site_lbl": "Thr649", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 649, "start_aa": "Thr", "end_pos": 649, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr649", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "F1LWT0-1", "start_pos": "677", "end_pos": "677", "site_lbl": "Thr677", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 677, "start_aa": "Thr", "end_pos": 677, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr677", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "F1LWT0-1", "start_pos": "808", "end_pos": "808", "site_lbl": "Thr808", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 808, "start_aa": "Thr", "end_pos": 808, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr808", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "F1LWT0-1" }, { "uniprot_canonical_ac": "M0R9A9-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "M0R9A9", "url": "https://www.uniprot.org/uniprotkb/M0R9A9" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 2053, "chemical_mass": 228843.0, "gene_names": "Cep164;Cep164;RGD1560988;RGD1561243", "protein_name": "Centrosomal protein of 164 kDa", "disease": [ { "disease_id": "DOID:0111123", "name": "nephronophthisis 15", "description": "A nephronophthisis that has_material_basis_in homozygous or compound heterozygous mutation in the CEP164 gene on chromosome 11q.", "url": "https://disease-ontology.org/term/DOID:0111123", "evidence": [ { "id": "0111123", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111123" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "M0R9A9", "url": "https://www.uniprot.org/uniprotkb/M0R9A9" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "M0R9A9", "url": "https://www.uniprot.org/uniprotkb/M0R9A9" } ], "pmid": "" }, { "name": "ciliary transition fiber", "id": "GO:0097539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097539", "evidence": [ { "database": "UniProtKB", "id": "M0R9A9", "url": "https://www.uniprot.org/uniprotkb/M0R9A9" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "M0R9A9", "url": "https://www.uniprot.org/uniprotkb/M0R9A9" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "M0R9A9", "url": "https://www.uniprot.org/uniprotkb/M0R9A9" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "M0R9A9", "url": "https://www.uniprot.org/uniprotkb/M0R9A9" } ], "pmid": "" }, { "name": "apical part of cell", "id": "GO:0045177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045177", "evidence": [ { "database": "UniProtKB", "id": "M0R9A9", "url": "https://www.uniprot.org/uniprotkb/M0R9A9" } ], "pmid": "" }, { "name": "9+2 motile cilium", "id": "GO:0097729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097729", "evidence": [ { "database": "UniProtKB", "id": "M0R9A9", "url": "https://www.uniprot.org/uniprotkb/M0R9A9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "M0R9A9", "url": "https://www.uniprot.org/uniprotkb/M0R9A9" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "M0R9A9", "url": "https://www.uniprot.org/uniprotkb/M0R9A9" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "M0R9A9", "url": "https://www.uniprot.org/uniprotkb/M0R9A9" } ], "pmid": "" }, { "name": "cell projection organization", "id": "GO:0030030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030030", "evidence": [ { "database": "UniProtKB", "id": "M0R9A9", "url": "https://www.uniprot.org/uniprotkb/M0R9A9" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "M0R9A9", "url": "https://www.uniprot.org/uniprotkb/M0R9A9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M0R9A9-1", "start_pos": "835", "end_pos": "835", "site_lbl": "Thr835", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 835, "start_aa": "Thr", "end_pos": 835, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr835", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "M0R9A9-1" }, { "uniprot_canonical_ac": "F1LUQ3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1LUQ3", "url": "https://www.uniprot.org/uniprotkb/F1LUQ3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 2058, "chemical_mass": 225060.0, "gene_names": "Tet1;Tet1", "protein_name": "Methylcytosine dioxygenase TET", "disease": [ { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 } ], "biological_process": [ { "name": "positive regulation of macromolecule biosynthetic process", "id": "GO:0010557", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010557", "evidence": [ { "database": "UniProtKB", "id": "F1LUQ3", "url": "https://www.uniprot.org/uniprotkb/F1LUQ3" } ], "pmid": "" }, { "name": "epigenetic regulation of gene expression", "id": "GO:0040029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040029", "evidence": [ { "database": "UniProtKB", "id": "F1LUQ3", "url": "https://www.uniprot.org/uniprotkb/F1LUQ3" } ], "pmid": "" }, { "name": "chromosomal 5-methylcytosine DNA demethylation pathway", "id": "GO:0141166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141166", "evidence": [ { "database": "UniProtKB", "id": "F1LUQ3", "url": "https://www.uniprot.org/uniprotkb/F1LUQ3" } ], "pmid": "" }, { "name": "positive regulation of gene expression via chromosomal CpG island demethylation", "id": "GO:0044029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044029", "evidence": [ { "database": "UniProtKB", "id": "F1LUQ3", "url": "https://www.uniprot.org/uniprotkb/F1LUQ3" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "F1LUQ3", "url": "https://www.uniprot.org/uniprotkb/F1LUQ3" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "F1LUQ3", "url": "https://www.uniprot.org/uniprotkb/F1LUQ3" } ], "pmid": "" }, { "name": "protein O-linked glycosylation", "id": "GO:0006493", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006493", "evidence": [ { "database": "UniProtKB", "id": "F1LUQ3", "url": "https://www.uniprot.org/uniprotkb/F1LUQ3" } ], "pmid": "" }, { "name": "stem cell population maintenance", "id": "GO:0019827", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019827", "evidence": [ { "database": "UniProtKB", "id": "F1LUQ3", "url": "https://www.uniprot.org/uniprotkb/F1LUQ3" } ], "pmid": "" }, { "name": "dendrite morphogenesis", "id": "GO:0048813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048813", "evidence": [ { "database": "UniProtKB", "id": "F1LUQ3", "url": "https://www.uniprot.org/uniprotkb/F1LUQ3" } ], "pmid": "" }, { "name": "cellular response to reactive oxygen species", "id": "GO:0034614", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034614", "evidence": [ { "database": "UniProtKB", "id": "F1LUQ3", "url": "https://www.uniprot.org/uniprotkb/F1LUQ3" } ], "pmid": "" }, { "name": "inner cell mass cell differentiation", "id": "GO:0001826", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001826", "evidence": [ { "database": "UniProtKB", "id": "F1LUQ3", "url": "https://www.uniprot.org/uniprotkb/F1LUQ3" } ], "pmid": "" }, { "name": "epigenetic programing of male pronucleus", "id": "GO:0044727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044727", "evidence": [ { "database": "UniProtKB", "id": "F1LUQ3", "url": "https://www.uniprot.org/uniprotkb/F1LUQ3" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "F1LUQ3", "url": "https://www.uniprot.org/uniprotkb/F1LUQ3" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1LUQ3", "url": "https://www.uniprot.org/uniprotkb/F1LUQ3" } ], "pmid": "" }, { "name": "DNA 5-methylcytosine dioxygenase activity", "id": "GO:0070579", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070579", "evidence": [ { "database": "UniProtKB", "id": "F1LUQ3", "url": "https://www.uniprot.org/uniprotkb/F1LUQ3" } ], "pmid": "" }, { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "F1LUQ3", "url": "https://www.uniprot.org/uniprotkb/F1LUQ3" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "F1LUQ3", "url": "https://www.uniprot.org/uniprotkb/F1LUQ3" } ], "pmid": "" }, { "name": "methyl-CpG binding", "id": "GO:0008327", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008327", "evidence": [ { "database": "UniProtKB", "id": "F1LUQ3", "url": "https://www.uniprot.org/uniprotkb/F1LUQ3" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1LUQ3", "url": "https://www.uniprot.org/uniprotkb/F1LUQ3" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "F1LUQ3", "url": "https://www.uniprot.org/uniprotkb/F1LUQ3" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1LUQ3", "url": "https://www.uniprot.org/uniprotkb/F1LUQ3" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "F1LUQ3", "url": "https://www.uniprot.org/uniprotkb/F1LUQ3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1LUQ3-1" }, { "uniprot_canonical_ac": "F1LSN6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1LSN6", "url": "https://www.uniprot.org/uniprotkb/F1LSN6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 5157, "chemical_mass": 582100.0, "gene_names": "Hydin;Hydin", "protein_name": "", "disease": [ { "disease_id": "DOID:0110617", "name": "primary ciliary dyskinesia 5", "description": "A primary ciliary dyskinesia that is characterized by autosomal recessive inheritance with early onset of a progressive decline in lung function and has_material_basis_in homozygous mutation in the HYDIN gene on chromosome 16q22.", "url": "https://disease-ontology.org/term/DOID:0110617", "evidence": [ { "id": "0110617", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110617" } ], "weight": 0.0 }, { "disease_id": "DOID:10908", "name": "hydrocephalus", "description": "A cerebral degeneration characterized by an abnormal accumulation of cerebrospinal fluid in the ventricles of the brain, leading to progressive enlargement of the head.", "url": "https://disease-ontology.org/term/DOID:10908", "evidence": [ { "id": "10908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10908" } ], "weight": 0.0 } ], "biological_process": [ { "name": "axonemal central apparatus assembly", "id": "GO:1904158", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904158", "evidence": [ { "database": "UniProtKB", "id": "F1LSN6", "url": "https://www.uniprot.org/uniprotkb/F1LSN6" } ], "pmid": "" }, { "name": "brain development", "id": "GO:0007420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420", "evidence": [ { "database": "UniProtKB", "id": "F1LSN6", "url": "https://www.uniprot.org/uniprotkb/F1LSN6" } ], "pmid": "" }, { "name": "ventricular system development", "id": "GO:0021591", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021591", "evidence": [ { "database": "UniProtKB", "id": "F1LSN6", "url": "https://www.uniprot.org/uniprotkb/F1LSN6" } ], "pmid": "" }, { "name": "cilium movement", "id": "GO:0003341", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003341", "evidence": [ { "database": "UniProtKB", "id": "F1LSN6", "url": "https://www.uniprot.org/uniprotkb/F1LSN6" } ], "pmid": "" }, { "name": "epithelial cell development", "id": "GO:0002064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002064", "evidence": [ { "database": "UniProtKB", "id": "F1LSN6", "url": "https://www.uniprot.org/uniprotkb/F1LSN6" } ], "pmid": "" }, { "name": "trachea development", "id": "GO:0060438", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060438", "evidence": [ { "database": "UniProtKB", "id": "F1LSN6", "url": "https://www.uniprot.org/uniprotkb/F1LSN6" } ], "pmid": "" } ], "cellular_component": [ { "name": "axonemal central apparatus", "id": "GO:1990716", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990716", "evidence": [ { "database": "UniProtKB", "id": "F1LSN6", "url": "https://www.uniprot.org/uniprotkb/F1LSN6" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "F1LSN6", "url": "https://www.uniprot.org/uniprotkb/F1LSN6" } ], "pmid": "" }, { "name": "sperm flagellum", "id": "GO:0036126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036126", "evidence": [ { "database": "UniProtKB", "id": "F1LSN6", "url": "https://www.uniprot.org/uniprotkb/F1LSN6" } ], "pmid": "" }, { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "F1LSN6", "url": "https://www.uniprot.org/uniprotkb/F1LSN6" } ], "pmid": "" }, { "name": "axonemal central pair projection", "id": "GO:1990718", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990718", "evidence": [ { "database": "UniProtKB", "id": "F1LSN6", "url": "https://www.uniprot.org/uniprotkb/F1LSN6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "F1LSN6-1", "start_pos": "1786", "end_pos": "1786", "site_lbl": "Thr1786", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1786, "start_aa": "Thr", "end_pos": 1786, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1786", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "F1LSN6-1", "start_pos": "270", "end_pos": "270", "site_lbl": "Thr270", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 270, "start_aa": "Thr", "end_pos": 270, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr270", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "F1LSN6-1", "start_pos": "4866", "end_pos": "4866", "site_lbl": "Thr4866", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 4866, "start_aa": "Thr", "end_pos": 4866, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr4866", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "F1LSN6-1" }, { "uniprot_canonical_ac": "A0A8I6A7C2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A7C2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A7C2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 211, "chemical_mass": 25118.0, "gene_names": "Rp9;RGD1559759;Rp9h;Rp9", "protein_name": "", "disease": [ { "disease_id": "DOID:0110387", "name": "retinitis pigmentosa 9", "description": "A retinitis pigmentosa that has_material_basis_in mutation in the RP9 gene on chromosome 7p14.", "url": "https://disease-ontology.org/term/DOID:0110387", "evidence": [ { "id": "0110387", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110387" } ], "weight": 0.0 } ], "biological_process": [ { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A7C2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A7C2" } ], "pmid": "" }, { "name": "cognition", "id": "GO:0050890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050890", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A7C2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A7C2" } ], "pmid": "" } ], "cellular_component": [ { "name": "signal recognition particle receptor complex", "id": "GO:0005785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005785", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A7C2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A7C2" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A7C2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A7C2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A7C2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A7C2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6A7C2-1" }, { "uniprot_canonical_ac": "A0A8I5Y120-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y120", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y120" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 591, "chemical_mass": 66863.0, "gene_names": "Brap;Brap", "protein_name": "BRCA1-associated protein", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y120", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y120" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y120", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y120" } ], "pmid": "" }, { "name": "ubiquitin ligase complex", "id": "GO:0000151", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000151", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y120", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y120" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y120", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y120" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y120", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y120" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y120", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y120" } ], "pmid": "" }, { "name": "nuclear localization sequence binding", "id": "GO:0008139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008139", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y120", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y120" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y120", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y120" } ], "pmid": "" }, { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y120", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y120" } ], "pmid": "" } ], "biological_process": [ { "name": "MAPK cascade", "id": "GO:0000165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000165", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y120", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y120" } ], "pmid": "" }, { "name": "Ras protein signal transduction", "id": "GO:0007265", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007265", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y120", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y120" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y120", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y120" } ], "pmid": "" }, { "name": "negative regulation of signal transduction", "id": "GO:0009968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009968", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y120", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y120" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5Y120-1" }, { "uniprot_canonical_ac": "A0A8I5ZSI8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZSI8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZSI8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 617, "chemical_mass": 69229.0, "gene_names": "Rtkn2", "protein_name": "", "disease": [], "biological_process": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZSI8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZSI8" } ], "pmid": "" }, { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZSI8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZSI8" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZSI8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZSI8" } ], "pmid": "" }, { "name": "positive regulation of non-canonical NF-kappaB signal transduction", "id": "GO:1901224", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901224", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZSI8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZSI8" } ], "pmid": "" }, { "name": "adaptive immune response", "id": "GO:0002250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002250", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZSI8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZSI8" } ], "pmid": "" }, { "name": "hemopoiesis", "id": "GO:0030097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030097", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZSI8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZSI8" } ], "pmid": "" }, { "name": "negative regulation of intrinsic apoptotic signaling pathway", "id": "GO:2001243", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001243", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZSI8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZSI8" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZSI8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZSI8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZSI8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZSI8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZSI8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZSI8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I5ZSI8-1", "start_pos": "584", "end_pos": "584", "site_lbl": "Thr584", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 584, "start_aa": "Thr", "end_pos": 584, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr584", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I5ZSI8-1" }, { "uniprot_canonical_ac": "A0A8I6AA24-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AA24", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AA24" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 743, "chemical_mass": 73450.0, "gene_names": "Col8a1;Col8a1", "protein_name": "", "disease": [ { "disease_id": "DOID:12930", "name": "dilated cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by an an enlarged heart and damage to the myocardium causing the heart to pump blood inefficiently.", "url": "https://disease-ontology.org/term/DOID:12930", "evidence": [ { "id": "12930", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12930" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AA24", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AA24" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AA24", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AA24" } ], "pmid": "" }, { "name": "collagen type VIII trimer", "id": "GO:0005591", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005591", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AA24", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AA24" } ], "pmid": "" } ], "biological_process": [ { "name": "extracellular matrix organization", "id": "GO:0030198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030198", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AA24", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AA24" } ], "pmid": "" }, { "name": "positive regulation of cell-substrate adhesion", "id": "GO:0010811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010811", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AA24", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AA24" } ], "pmid": "" }, { "name": "camera-type eye morphogenesis", "id": "GO:0048593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048593", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AA24", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AA24" } ], "pmid": "" }, { "name": "endodermal cell differentiation", "id": "GO:0035987", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035987", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AA24", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AA24" } ], "pmid": "" }, { "name": "epithelial cell proliferation", "id": "GO:0050673", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050673", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AA24", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AA24" } ], "pmid": "" } ], "molecular_function": [ { "name": "extracellular matrix structural constituent conferring tensile strength", "id": "GO:0030020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030020", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AA24", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AA24" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6AA24-1", "start_pos": "577", "end_pos": "577", "site_lbl": "Thr577", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 577, "start_aa": "Thr", "end_pos": 577, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr577", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6AA24-1" }, { "uniprot_canonical_ac": "A0A8I6B6E7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B6E7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B6E7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 190, "chemical_mass": 21621.0, "gene_names": "Rnf183;RGD1564412;Rnf183", "protein_name": "", "disease": [], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B6E7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B6E7" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B6E7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B6E7" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B6E7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B6E7" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B6E7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B6E7" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B6E7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B6E7" } ], "pmid": "" }, { "name": "cis-Golgi network membrane", "id": "GO:0033106", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033106", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B6E7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B6E7" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway", "id": "GO:1902237", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902237", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B6E7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B6E7" } ], "pmid": "" }, { "name": "protein polyubiquitination", "id": "GO:0000209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000209", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B6E7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B6E7" } ], "pmid": "" }, { "name": "protein autoubiquitination", "id": "GO:0051865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051865", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B6E7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B6E7" } ], "pmid": "" }, { "name": "response to endoplasmic reticulum stress", "id": "GO:0034976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034976", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B6E7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B6E7" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B6E7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B6E7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6B6E7-1" }, { "uniprot_canonical_ac": "A0A8I6A823-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A823", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A823" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 455, "chemical_mass": 51918.0, "gene_names": "Mfsd13b;LOC691551;Mfsd13b", "protein_name": "", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A823", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A823" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6A823-1" }, { "uniprot_canonical_ac": "M0RB79-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "M0RB79", "url": "https://www.uniprot.org/uniprotkb/M0RB79" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 222, "chemical_mass": 24621.0, "gene_names": "Cd300c2l1;Cd300c2l1;RGD1562667", "protein_name": "", "disease": [], "molecular_function": [ { "name": "transmembrane signaling receptor activity", "id": "GO:0004888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004888", "evidence": [ { "database": "UniProtKB", "id": "M0RB79", "url": "https://www.uniprot.org/uniprotkb/M0RB79" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "M0RB79", "url": "https://www.uniprot.org/uniprotkb/M0RB79" } ], "pmid": "" } ], "biological_process": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "M0RB79", "url": "https://www.uniprot.org/uniprotkb/M0RB79" } ], "pmid": "" }, { "name": "regulation of innate immune response", "id": "GO:0045088", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045088", "evidence": [ { "database": "UniProtKB", "id": "M0RB79", "url": "https://www.uniprot.org/uniprotkb/M0RB79" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M0RB79-1" }, { "uniprot_canonical_ac": "F7EWC1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F7EWC1", "url": "https://www.uniprot.org/uniprotkb/F7EWC1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 451, "chemical_mass": 47447.0, "gene_names": "Vasp", "protein_name": "Vasodilator-stimulated phosphoprotein", "disease": [ { "disease_id": "DOID:680", "name": "tauopathy", "description": "A neurodegenerative disease that has_material_basis_in the pathological aggregation of tau protein in so-called neurofibrillary tangles (NFT) in the human brain.", "url": "https://disease-ontology.org/term/DOID:680", "evidence": [ { "id": "680", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:680" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "F7EWC1", "url": "https://www.uniprot.org/uniprotkb/F7EWC1" } ], "pmid": "" }, { "name": "SH3 domain binding", "id": "GO:0017124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017124", "evidence": [ { "database": "UniProtKB", "id": "F7EWC1", "url": "https://www.uniprot.org/uniprotkb/F7EWC1" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "F7EWC1", "url": "https://www.uniprot.org/uniprotkb/F7EWC1" } ], "pmid": "" }, { "name": "profilin binding", "id": "GO:0005522", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005522", "evidence": [ { "database": "UniProtKB", "id": "F7EWC1", "url": "https://www.uniprot.org/uniprotkb/F7EWC1" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F7EWC1", "url": "https://www.uniprot.org/uniprotkb/F7EWC1" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "F7EWC1", "url": "https://www.uniprot.org/uniprotkb/F7EWC1" } ], "pmid": "" }, { "name": "lamellipodium", "id": "GO:0030027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030027", "evidence": [ { "database": "UniProtKB", "id": "F7EWC1", "url": "https://www.uniprot.org/uniprotkb/F7EWC1" } ], "pmid": "" }, { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "F7EWC1", "url": "https://www.uniprot.org/uniprotkb/F7EWC1" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F7EWC1", "url": "https://www.uniprot.org/uniprotkb/F7EWC1" } ], "pmid": "" }, { "name": "focal adhesion", "id": "GO:0005925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005925", "evidence": [ { "database": "UniProtKB", "id": "F7EWC1", "url": "https://www.uniprot.org/uniprotkb/F7EWC1" } ], "pmid": "" }, { "name": "cell junction", "id": "GO:0030054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030054", "evidence": [ { "database": "UniProtKB", "id": "F7EWC1", "url": "https://www.uniprot.org/uniprotkb/F7EWC1" } ], "pmid": "" }, { "name": "postsynapse", "id": "GO:0098794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098794", "evidence": [ { "database": "UniProtKB", "id": "F7EWC1", "url": "https://www.uniprot.org/uniprotkb/F7EWC1" } ], "pmid": "" }, { "name": "filopodium", "id": "GO:0030175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030175", "evidence": [ { "database": "UniProtKB", "id": "F7EWC1", "url": "https://www.uniprot.org/uniprotkb/F7EWC1" } ], "pmid": "" } ], "biological_process": [ { "name": "filopodium assembly", "id": "GO:0046847", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046847", "evidence": [ { "database": "UniProtKB", "id": "F7EWC1", "url": "https://www.uniprot.org/uniprotkb/F7EWC1" } ], "pmid": "" }, { "name": "protein homotetramerization", "id": "GO:0051289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051289", "evidence": [ { "database": "UniProtKB", "id": "F7EWC1", "url": "https://www.uniprot.org/uniprotkb/F7EWC1" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "F7EWC1", "url": "https://www.uniprot.org/uniprotkb/F7EWC1" } ], "pmid": "" }, { "name": "actin polymerization or depolymerization", "id": "GO:0008154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008154", "evidence": [ { "database": "UniProtKB", "id": "F7EWC1", "url": "https://www.uniprot.org/uniprotkb/F7EWC1" } ], "pmid": "" }, { "name": "neural tube closure", "id": "GO:0001843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001843", "evidence": [ { "database": "UniProtKB", "id": "F7EWC1", "url": "https://www.uniprot.org/uniprotkb/F7EWC1" } ], "pmid": "" }, { "name": "actin filament polymerization", "id": "GO:0030041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030041", "evidence": [ { "database": "UniProtKB", "id": "F7EWC1", "url": "https://www.uniprot.org/uniprotkb/F7EWC1" } ], "pmid": "" }, { "name": "positive regulation of actin filament polymerization", "id": "GO:0030838", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030838", "evidence": [ { "database": "UniProtKB", "id": "F7EWC1", "url": "https://www.uniprot.org/uniprotkb/F7EWC1" } ], "pmid": "" }, { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "F7EWC1", "url": "https://www.uniprot.org/uniprotkb/F7EWC1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F7EWC1-1" }, { "uniprot_canonical_ac": "A0A096MK85-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A096MK85", "url": "https://www.uniprot.org/uniprotkb/A0A096MK85" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 303, "chemical_mass": 32126.0, "gene_names": "Susd6;LOC678893;Susd6", "protein_name": "", "disease": [], "biological_process": [ { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "A0A096MK85", "url": "https://www.uniprot.org/uniprotkb/A0A096MK85" } ], "pmid": "" } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A096MK85", "url": "https://www.uniprot.org/uniprotkb/A0A096MK85" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A096MK85-1" }, { "uniprot_canonical_ac": "F7FPR5-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F7FPR5", "url": "https://www.uniprot.org/uniprotkb/F7FPR5" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 285, "chemical_mass": 31596.0, "gene_names": "Clec2d2l2;Clec2d2l2;Clec2d4;Clr4;LOC689770", "protein_name": "", "disease": [], "molecular_function": [ { "name": "natural killer cell lectin-like receptor binding", "id": "GO:0046703", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046703", "evidence": [ { "database": "UniProtKB", "id": "F7FPR5", "url": "https://www.uniprot.org/uniprotkb/F7FPR5" } ], "pmid": "" }, { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "F7FPR5", "url": "https://www.uniprot.org/uniprotkb/F7FPR5" } ], "pmid": "" }, { "name": "receptor ligand activity", "id": "GO:0048018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048018", "evidence": [ { "database": "UniProtKB", "id": "F7FPR5", "url": "https://www.uniprot.org/uniprotkb/F7FPR5" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F7FPR5", "url": "https://www.uniprot.org/uniprotkb/F7FPR5" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "F7FPR5", "url": "https://www.uniprot.org/uniprotkb/F7FPR5" } ], "pmid": "" } ], "biological_process": [ { "name": "T cell receptor signaling pathway", "id": "GO:0050852", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050852", "evidence": [ { "database": "UniProtKB", "id": "F7FPR5", "url": "https://www.uniprot.org/uniprotkb/F7FPR5" } ], "pmid": "" }, { "name": "NK T cell activation", "id": "GO:0051132", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051132", "evidence": [ { "database": "UniProtKB", "id": "F7FPR5", "url": "https://www.uniprot.org/uniprotkb/F7FPR5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F7FPR5-1" }, { "uniprot_canonical_ac": "F1LXN6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1LXN6", "url": "https://www.uniprot.org/uniprotkb/F1LXN6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 660, "chemical_mass": 72895.0, "gene_names": "LOC120101643", "protein_name": "Sodium/nucleoside cotransporter", "disease": [], "molecular_function": [ { "name": "purine nucleoside transmembrane transporter activity", "id": "GO:0015211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015211", "evidence": [ { "database": "UniProtKB", "id": "F1LXN6", "url": "https://www.uniprot.org/uniprotkb/F1LXN6" } ], "pmid": "" }, { "name": "nucleoside:sodium symporter activity", "id": "GO:0005415", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005415", "evidence": [ { "database": "UniProtKB", "id": "F1LXN6", "url": "https://www.uniprot.org/uniprotkb/F1LXN6" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1LXN6", "url": "https://www.uniprot.org/uniprotkb/F1LXN6" } ], "pmid": "" } ], "biological_process": [ { "name": "retina homeostasis", "id": "GO:0001895", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001895", "evidence": [ { "database": "UniProtKB", "id": "F1LXN6", "url": "https://www.uniprot.org/uniprotkb/F1LXN6" } ], "pmid": "" }, { "name": "nucleoside transmembrane transport", "id": "GO:1901642", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901642", "evidence": [ { "database": "UniProtKB", "id": "F1LXN6", "url": "https://www.uniprot.org/uniprotkb/F1LXN6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1LXN6-1" }, { "uniprot_canonical_ac": "F1LZT7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1LZT7", "url": "https://www.uniprot.org/uniprotkb/F1LZT7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 633, "chemical_mass": 70327.0, "gene_names": "Slc6a20b;Slc6a20b", "protein_name": "Transporter", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1LZT7", "url": "https://www.uniprot.org/uniprotkb/F1LZT7" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1LZT7", "url": "https://www.uniprot.org/uniprotkb/F1LZT7" } ], "pmid": "" }, { "name": "symporter activity", "id": "GO:0015293", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015293", "evidence": [ { "database": "UniProtKB", "id": "F1LZT7", "url": "https://www.uniprot.org/uniprotkb/F1LZT7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1LZT7-1" }, { "uniprot_canonical_ac": "A0A8I6AFZ5-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AFZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AFZ5" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 238, "chemical_mass": 27378.0, "gene_names": "Srsf7;Sfrs7;Srsf7", "protein_name": "Serine/arginine-rich splicing factor 7", "disease": [ { "disease_id": "DOID:4467", "name": "clear cell renal cell carcinoma", "description": "A renal cell carcinoma that has_material_basis_in cells that appear very pale or clear when examined under microscope.", "url": "https://disease-ontology.org/term/DOID:4467", "evidence": [ { "id": "4467", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4467" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AFZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AFZ5" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AFZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AFZ5" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AFZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AFZ5" } ], "pmid": "" }, { "name": "protein domain specific binding", "id": "GO:0019904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019904", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AFZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AFZ5" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AFZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AFZ5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AFZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AFZ5" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AFZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AFZ5" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AFZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AFZ5" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AFZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AFZ5" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AFZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AFZ5" } ], "pmid": "" }, { "name": "mRNA transport", "id": "GO:0051028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051028", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AFZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AFZ5" } ], "pmid": "" }, { "name": "cellular response to leukemia inhibitory factor", "id": "GO:1990830", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990830", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AFZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AFZ5" } ], "pmid": "" }, { "name": "negative regulation of mRNA splicing, via spliceosome", "id": "GO:0048025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048025", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AFZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AFZ5" } ], "pmid": "" }, { "name": "regulation of alternative mRNA splicing, via spliceosome", "id": "GO:0000381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000381", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AFZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AFZ5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AFZ5-1" }, { "uniprot_canonical_ac": "A0A8I5ZLK2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZLK2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZLK2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 147, "chemical_mass": 16706.0, "gene_names": "Mgst2;Mgst2", "protein_name": "Microsomal glutathione S-transferase 2", "disease": [], "molecular_function": [ { "name": "glutathione transferase activity", "id": "GO:0004364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004364", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZLK2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZLK2" } ], "pmid": "" }, { "name": "glutathione binding", "id": "GO:0043295", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043295", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZLK2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZLK2" } ], "pmid": "" }, { "name": "leukotriene-C4 synthase activity", "id": "GO:0004464", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004464", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZLK2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZLK2" } ], "pmid": "" }, { "name": "enzyme activator activity", "id": "GO:0008047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008047", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZLK2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZLK2" } ], "pmid": "" }, { "name": "glutathione peroxidase activity", "id": "GO:0004602", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004602", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZLK2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZLK2" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZLK2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZLK2" } ], "pmid": "" } ], "biological_process": [ { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZLK2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZLK2" } ], "pmid": "" }, { "name": "leukotriene biosynthetic process", "id": "GO:0019370", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019370", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZLK2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZLK2" } ], "pmid": "" }, { "name": "glutathione biosynthetic process", "id": "GO:0006750", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006750", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZLK2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZLK2" } ], "pmid": "" }, { "name": "response to lipopolysaccharide", "id": "GO:0032496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032496", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZLK2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZLK2" } ], "pmid": "" }, { "name": "membrane lipid catabolic process", "id": "GO:0046466", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046466", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZLK2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZLK2" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZLK2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZLK2" } ], "pmid": "" }, { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZLK2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZLK2" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZLK2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZLK2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZLK2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZLK2" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZLK2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZLK2" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZLK2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZLK2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZLK2-1" }, { "uniprot_canonical_ac": "A0A8I6A254-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A254", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A254" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 295, "chemical_mass": 33652.0, "gene_names": "Mrpl15;Mrpl15", "protein_name": "Large ribosomal subunit protein uL15m", "disease": [ { "disease_id": "DOID:11198", "name": "DiGeorge syndrome", "description": "A syndrome that has_material_basis_in a large deletion of the chromosome 22q11.2 region which includes the DGS gene needed for development of the thymus and related glands with subsequent lack of T-cell production.", "url": "https://disease-ontology.org/term/DOID:11198", "evidence": [ { "id": "11198", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11198" } ], "weight": 0.0 } ], "biological_process": [ { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A254", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A254" } ], "pmid": "" }, { "name": "cellular response to leukemia inhibitory factor", "id": "GO:1990830", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990830", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A254", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A254" } ], "pmid": "" } ], "molecular_function": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A254", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A254" } ], "pmid": "" } ], "cellular_component": [ { "name": "large ribosomal subunit", "id": "GO:0015934", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015934", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A254", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A254" } ], "pmid": "" }, { "name": "mitochondrial large ribosomal subunit", "id": "GO:0005762", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005762", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A254", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A254" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A254", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A254" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6A254-1" }, { "uniprot_canonical_ac": "A0A8I6A4C5-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A4C5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A4C5" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 694, "chemical_mass": 78651.0, "gene_names": "Mthfr;Mthfr", "protein_name": "Methylenetetrahydrofolate reductase", "disease": [ { "disease_id": "DOID:0050589", "name": "inflammatory bowel disease", "description": "An intestinal disease characterized by inflammation located in all parts of digestive tract.", "url": "https://disease-ontology.org/term/DOID:0050589", "evidence": [ { "id": "0050589", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050589" } ], "weight": 0.0 }, { "disease_id": "DOID:0050745", "name": "diffuse large B-cell lymphoma", "description": "A large B-cell lymphoma that is consisting of medium-sized to large B cells with a diffuse growth pattern.", "url": "https://disease-ontology.org/term/DOID:0050745", "evidence": [ { "id": "0050745", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050745" } ], "weight": 0.0 }, { "disease_id": "DOID:0050830", "name": "peripheral artery disease", "description": "An artery disease that is characterized by build up of plaque in the arteries that carry blood to your head, organs, and limbs.", "url": "https://disease-ontology.org/term/DOID:0050830", "evidence": [ { "id": "0050830", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050830" } ], "weight": 0.0 }, { "disease_id": "DOID:0050864", "name": "non-arteritic anterior ischemic optic neuropathy", "description": "An anterior ischemic optic neuropathy that is characterized by near-complete vision loss caused by acute ischemic damage to the optic nerve due to non-inflammatory small vessel disease.", "url": "https://disease-ontology.org/term/DOID:0050864", "evidence": [ { "id": "0050864", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050864" } ], "weight": 0.0 }, { "disease_id": "DOID:0050866", "name": "oral squamous cell carcinoma", "description": "An oral cavity cancer that has_material_basis_in squamous cells.", "url": "https://disease-ontology.org/term/DOID:0050866", "evidence": [ { "id": "0050866", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050866" } ], "weight": 0.0 }, { "disease_id": "DOID:0051054", "name": "coarctation of the aorta", "description": "A congenital heart disease that is characterized by the luminal narrowing of the thoracic aortic arch, typically located just beyond the left subclavian artery. This narrowing creates an obstruction that can lead to significant cardiovascular complications, including systemic hypertension, left ventricular hypertrophy, and eventually heart failure.", "url": "https://disease-ontology.org/term/DOID:0051054", "evidence": [ { "id": "0051054", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0051054" } ], "weight": 0.0 }, { "disease_id": "DOID:0051061", "name": "stroke", "description": "A cerebrovascular disease that is characterized by disruption of blood flow to the brain resulting in damage to brain cells due to a lack of oxygen.", "url": "https://disease-ontology.org/term/DOID:0051061", "evidence": [ { "id": "0051061", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0051061" } ], "weight": 0.0 }, { "disease_id": "DOID:0060770", "name": "dextro-looped transposition of the great arteries", "description": "A congenital heart disease characterized by complete inversion of the great vessels where the aorta incorrectly arises from the right ventricle and the pulmonary artery incorrectly arises from the left ventricle.", "url": "https://disease-ontology.org/term/DOID:0060770", "evidence": [ { "id": "0060770", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060770" } ], "weight": 0.0 }, { "disease_id": "DOID:0070004", "name": "myeloid neoplasm", "description": "A bone marrow cancer that is formed of any one of the bone marrow cells belonging to the granulocytic (neutrophil, eosinophil, basophil), monocytic/macrophage, erythroid, megakaryocytic and mast cell lineages.", "url": "https://disease-ontology.org/term/DOID:0070004", "evidence": [ { "id": "0070004", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070004" } ], "weight": 0.0 }, { "disease_id": "DOID:0080016", "name": "spina bifida", "description": "A neural tube defect that is characterized by incomplete closing of the spine and membranes around the spinal cord during early development.", "url": "https://disease-ontology.org/term/DOID:0080016", "evidence": [ { "id": "0080016", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080016" } ], "weight": 0.0 }, { "disease_id": "DOID:0080074", "name": "neural tube defect", "description": "A physical disorder characterized by incomplete closure of the neural tube.", "url": "https://disease-ontology.org/term/DOID:0080074", "evidence": [ { "id": "0080074", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080074" } ], "weight": 0.0 }, { "disease_id": "DOID:0080177", "name": "hepatic veno-occlusive disease", "description": "A hepatic vascular disease that is characterized by obstruction of some of the small veins of the liver.", "url": "https://disease-ontology.org/term/DOID:0080177", "evidence": [ { "id": "0080177", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080177" } ], "weight": 0.0 }, { "disease_id": "DOID:0080208", "name": "metabolic dysfunction-associated steatotic liver disease", "description": "A steatotic liver disease characterized by at least one of five specified cardiometabolic risk factors and no other discernible cause with normal to no alcohol use. The five cardiometabolic risk factors are: (1) higher than normal body mass index or waist circumference; (2) higher than normal serum glucose or glycated hemoglobin level, or type 2 diabetes; (3) higher than normal blood pressure or hypertensive treatment; (4) higher than normal plasma triglycerides or lipid lowering treatment; and (5) lower than normal plasma high-density lipoprotein cholesterol.", "url": "https://disease-ontology.org/term/DOID:0080208", "evidence": [ { "id": "0080208", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080208" } ], "weight": 0.0 }, { "disease_id": "DOID:0081267", "name": "graft-versus-host disease", "description": "An immune system disease that is characterized by recognition by mature donor T cells, that contaminate the allogeneic bone marrow, of the recipient's tissue as foreign, causing a severe inflammatory disease characterized by rashes, diarrhea, and liver disease, and that has_material_basis_in an associated with variation in the interleukin-10 gene (IL10) on chromosome 1q32.", "url": "https://disease-ontology.org/term/DOID:0081267", "evidence": [ { "id": "0081267", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081267" } ], "weight": 0.0 }, { "disease_id": "DOID:0111907", "name": "thrombophilia due to thrombin defect", "description": "A thrombophilia characterized by recurrent thrombophilia that has_material_basis_in heterozygous mutation in F2 on chromosome 11p11.2.", "url": "https://disease-ontology.org/term/DOID:0111907", "evidence": [ { "id": "0111907", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111907" } ], "weight": 0.0 }, { "disease_id": "DOID:10024", "name": "migraine with aura", "description": "A migraine characterized by migraine headache which is preceded or accompanied by a transient focal neurological phenomenon.", "url": "https://disease-ontology.org/term/DOID:10024", "evidence": [ { "id": "10024", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10024" } ], "weight": 0.0 }, { "disease_id": "DOID:1067", "name": "open-angle glaucoma", "description": "A glaucoma characterized by optic nerve damage resulting in progressive loss of visual field and increased pressure in the eye due to trabecular blockage.", "url": "https://disease-ontology.org/term/DOID:1067", "evidence": [ { "id": "1067", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1067" } ], "weight": 0.0 }, { "disease_id": "DOID:1074", "name": "kidney failure", "description": "A kidney disease characterized by the failure of the kidneys to adequately filter waste products from the blood.", "url": "https://disease-ontology.org/term/DOID:1074", "evidence": [ { "id": "1074", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1074" } ], "weight": 0.0 }, { "disease_id": "DOID:10873", "name": "Kuhnt-Junius degeneration", "description": "", "url": "https://disease-ontology.org/term/DOID:10873", "evidence": [ { "id": "10873", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10873" } ], "weight": 0.0 }, { "disease_id": "DOID:10923", "name": "sickle cell anemia", "description": "A sickle cell disease that is characterized by the replacement of both of the beta-globin subunits in hemoglobin with hemoglobin S, resulting in a low number of red blood cells, repeated infections, and periodic episodes of pain.", "url": "https://disease-ontology.org/term/DOID:10923", "evidence": [ { "id": "10923", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10923" } ], "weight": 0.0 }, { "disease_id": "DOID:1094", "name": "attention deficit hyperactivity disorder", "description": "A specific developmental disorder that is characterized by co-existence of attentional problems and hyperactivity, with each behavior occurring infrequently alone and symptoms starting before seven years of age.", "url": "https://disease-ontology.org/term/DOID:1094", "evidence": [ { "id": "1094", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1094" } ], "weight": 0.0 }, { "disease_id": "DOID:11054", "name": "urinary bladder cancer", "description": "An urinary system cancer that results_in malignant growth located_in the urinary bladder.", "url": "https://disease-ontology.org/term/DOID:11054", "evidence": [ { "id": "11054", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11054" } ], "weight": 0.0 }, { "disease_id": "DOID:11512", "name": "Budd-Chiari syndrome", "description": "A hepatic vascular disease that is characterized by a spectrum of disease states, including anatomic abnormalities and hypercoagulable disorders, resulting in hepatic venous outflow occlusion.", "url": "https://disease-ontology.org/term/DOID:11512", "evidence": [ { "id": "11512", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11512" } ], "weight": 0.0 }, { "disease_id": "DOID:11664", "name": "nephrosclerosis", "description": "", "url": "https://disease-ontology.org/term/DOID:11664", "evidence": [ { "id": "11664", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11664" } ], "weight": 0.0 }, { "disease_id": "DOID:11695", "name": "portal vein thrombosis", "description": "A hepatic vascular disease that is characterized by a blood clot that forms within the hepatic portal vein.", "url": "https://disease-ontology.org/term/DOID:11695", "evidence": [ { "id": "11695", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11695" } ], "weight": 0.0 }, { "disease_id": "DOID:12134", "name": "factor VIII deficiency", "description": "A hemophilia that has_material_basis_in Factor VIII deficiency, which results in the formation of fibrin deficient clots which makes coagulation much more prolonged.", "url": "https://disease-ontology.org/term/DOID:12134", "evidence": [ { "id": "12134", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12134" } ], "weight": 0.0 }, { "disease_id": "DOID:12336", "name": "male infertility", "description": "", "url": "https://disease-ontology.org/term/DOID:12336", "evidence": [ { "id": "12336", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12336" } ], "weight": 0.0 }, { "disease_id": "DOID:12361", "name": "Graves' disease", "description": "An autoimmune disease of endocrine system that involves production of excessive amount of thyroid hormones, located_in thyroid gland.", "url": "https://disease-ontology.org/term/DOID:12361", "evidence": [ { "id": "12361", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12361" } ], "weight": 0.0 }, { "disease_id": "DOID:1287", "name": "cardiovascular system disease", "description": "A disease of anatomical entity which occurs in the blood, heart, blood vessels or the lymphatic system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells or lymph to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis.", "url": "https://disease-ontology.org/term/DOID:1287", "evidence": [ { "id": "1287", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1287" } ], "weight": 0.0 }, { "disease_id": "DOID:13001", "name": "carotid stenosis", "description": "", "url": "https://disease-ontology.org/term/DOID:13001", "evidence": [ { "id": "13001", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13001" } ], "weight": 0.0 }, { "disease_id": "DOID:13550", "name": "angle-closure glaucoma", "description": "A glaucoma characterized by closure of the anterior chamber angle such that aqueous outflow is blocked and the intraocular pressure becomes inappropriately elevated leading to optic nerve damage and visual field loss. Angle-closure glaucoma has_symptom progressive peripheral vision loss, decreased vision, and pain, redness, and headache in acute cases. Angle closure glaucoma can be caused by anatomically narrow angle, injury to the trabecular meshwork, and injuries to the anterior chamber, such as neovascularization and uveitis.", "url": "https://disease-ontology.org/term/DOID:13550", "evidence": [ { "id": "13550", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13550" } ], "weight": 0.0 }, { "disease_id": "DOID:14018", "name": "alcoholic liver cirrhosis", "description": "", "url": "https://disease-ontology.org/term/DOID:14018", "evidence": [ { "id": "14018", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14018" } ], "weight": 0.0 }, { "disease_id": "DOID:14250", "name": "Down syndrome", "description": "A chromosomal duplication syndrome that is characterized by flat-looking facial features and weak muscle tone (hypotonia) in infancy and is caused by trisomy of all or a critical portion of chromosome 21 and is associated with intellectual disability.", "url": "https://disease-ontology.org/term/DOID:14250", "evidence": [ { "id": "14250", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14250" } ], "weight": 0.0 }, { "disease_id": "DOID:1459", "name": "hypothyroidism", "description": "A thyroid gland disease which involves an underproduction of thyroid hormone.", "url": "https://disease-ontology.org/term/DOID:1459", "evidence": [ { "id": "1459", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1459" } ], "weight": 0.0 }, { "disease_id": "DOID:1588", "name": "thrombocytopenia", "description": "A blood platelet disease that is characterized by low a platelet count in the blood.", "url": "https://disease-ontology.org/term/DOID:1588", "evidence": [ { "id": "1588", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1588" } ], "weight": 0.0 }, { "disease_id": "DOID:1727", "name": "retinal vein occlusion", "description": "", "url": "https://disease-ontology.org/term/DOID:1727", "evidence": [ { "id": "1727", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1727" } ], "weight": 0.0 }, { "disease_id": "DOID:1749", "name": "squamous cell carcinoma", "description": "A carcinoma that derives_from squamous epithelial cells.", "url": "https://disease-ontology.org/term/DOID:1749", "evidence": [ { "id": "1749", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1749" } ], "weight": 0.0 }, { "disease_id": "DOID:1793", "name": "pancreatic cancer", "description": "An endocrine gland cancer located_in the pancreas.", "url": "https://disease-ontology.org/term/DOID:1793", "evidence": [ { "id": "1793", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1793" } ], "weight": 0.0 }, { "disease_id": "DOID:1936", "name": "atherosclerosis", "description": "An arteriosclerotic cardiovascular disease that is characterized by the build-up of fatty material and calcium deposition in the arterial wall resulting in partial or complete occlusion of the arterial lumen. Disease is located within the tunica intima of large and small arteries.", "url": "https://disease-ontology.org/term/DOID:1936", "evidence": [ { "id": "1936", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1936" } ], "weight": 0.0 }, { "disease_id": "DOID:1984", "name": "rectal benign neoplasm", "description": "An intestinal benign neoplasm located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:1984", "evidence": [ { "id": "1984", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1984" } ], "weight": 0.0 }, { "disease_id": "DOID:2043", "name": "hepatitis B", "description": "A viral hepatitis that results_in inflammation located_in liver, has_material_basis_in Hepatitis B virus (Orthohepadnavirus hominoidei), which is transmitted_by sexual contact, blood transfusions, or fomites like needles or syringes. The infection has_symptom fever, fatigue, loss of appetite, nausea, vomiting, abdominal pain, clay-colored bowel movements, joint pain, and jaundice.", "url": "https://disease-ontology.org/term/DOID:2043", "evidence": [ { "id": "2043", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2043" } ], "weight": 0.0 }, { "disease_id": "DOID:2154", "name": "nephroblastoma", "description": "A kidney cancer that affects the kidneys and typically occuring in children.", "url": "https://disease-ontology.org/term/DOID:2154", "evidence": [ { "id": "2154", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2154" } ], "weight": 0.0 }, { "disease_id": "DOID:2355", "name": "anemia", "description": "A hematopoietic system disease that is characterized by a decrease in the normal number of red blood cells.", "url": "https://disease-ontology.org/term/DOID:2355", "evidence": [ { "id": "2355", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2355" } ], "weight": 0.0 }, { "disease_id": "DOID:2388", "name": "renal artery disease", "description": "", "url": "https://disease-ontology.org/term/DOID:2388", "evidence": [ { "id": "2388", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2388" } ], "weight": 0.0 }, { "disease_id": "DOID:2452", "name": "thrombophilia", "description": "A blood coagulation disease that is characterized by an increased tendency to form clots.", "url": "https://disease-ontology.org/term/DOID:2452", "evidence": [ { "id": "2452", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2452" } ], "weight": 0.0 }, { "disease_id": "DOID:2671", "name": "transitional cell carcinoma", "description": "A carcinoma that derives_from transitional epithelial cells.", "url": "https://disease-ontology.org/term/DOID:2671", "evidence": [ { "id": "2671", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2671" } ], "weight": 0.0 }, { "disease_id": "DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.", "url": "https://disease-ontology.org/term/DOID:2841", "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ], "weight": 0.0 }, { "disease_id": "DOID:2921", "name": "glomerulonephritis", "description": "A nephritis that causes inflammation of the glomeruli located_in kidney.", "url": "https://disease-ontology.org/term/DOID:2921", "evidence": [ { "id": "2921", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2921" } ], "weight": 0.0 }, { "disease_id": "DOID:2987", "name": "familial Mediterranean fever", "description": "An autoinflammatory disease characterized by recurrent episodes of fever and acute inflammation of the membranes lining the abdomen, joints and lungs; that has_material_basis_in mutations in the MEFV gene, which encodes the protein pyrin.", "url": "https://disease-ontology.org/term/DOID:2987", "evidence": [ { "id": "2987", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2987" } ], "weight": 0.0 }, { "disease_id": "DOID:3146", "name": "lipid metabolism disorder", "description": "An inherited metabolic disorder that involves the creation and degradation of lipids.", "url": "https://disease-ontology.org/term/DOID:3146", "evidence": [ { "id": "3146", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3146" } ], "weight": 0.0 }, { "disease_id": "DOID:326", "name": "ischemia", "description": "A vascular disease that is characterized by a restriction in blood supply to tissues.", "url": "https://disease-ontology.org/term/DOID:326", "evidence": [ { "id": "326", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:326" } ], "weight": 0.0 }, { "disease_id": "DOID:332", "name": "amyotrophic lateral sclerosis", "description": "A motor neuron disease that is characterized by muscle spasticity, rapidly progressive weakness due to muscle atrophy, difficulty in speaking, swallowing, and breathing.", "url": "https://disease-ontology.org/term/DOID:332", "evidence": [ { "id": "332", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:332" } ], "weight": 0.0 }, { "disease_id": "DOID:3347", "name": "osteosarcoma", "description": "A bone sarcoma that is located_in bone that has_material_basis_in cells of mesenchymal origin. It usually involves bones and less frequently extraosseous sites. It often involves the long bones (particularly distal femur, proximal tibia, and proximal humerus).", "url": "https://disease-ontology.org/term/DOID:3347", "evidence": [ { "id": "3347", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3347" } ], "weight": 0.0 }, { "disease_id": "DOID:3393", "name": "coronary artery disease", "description": "An artery disease that is characterized by plaque building up along the inner walls of the arteries of the heart resulting in a narrowing of the arteries and a reduced blood supply to the cardiac muscles.", "url": "https://disease-ontology.org/term/DOID:3393", "evidence": [ { "id": "3393", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3393" } ], "weight": 0.0 }, { "disease_id": "DOID:3526", "name": "cerebral infarction", "description": "A cerebrovascular disease that is characterized by an area of necrotic tissue in the brain resulting from a blockage or narrowing in the arteries supplying blood and oxygen to the brain.", "url": "https://disease-ontology.org/term/DOID:3526", "evidence": [ { "id": "3526", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3526" } ], "weight": 0.0 }, { "disease_id": "DOID:4362", "name": "cervical cancer", "description": "A female reproductive organ cancer that is located_in the cervix.", "url": "https://disease-ontology.org/term/DOID:4362", "evidence": [ { "id": "4362", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4362" } ], "weight": 0.0 }, { "disease_id": "DOID:4450", "name": "renal cell carcinoma", "description": "A renal carcinoma that has_material_basis_in the lining of the proximal convoluted renal tubule of the kidney.", "url": "https://disease-ontology.org/term/DOID:4450", "evidence": [ { "id": "4450", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4450" } ], "weight": 0.0 }, { "disease_id": "DOID:4467", "name": "clear cell renal cell carcinoma", "description": "A renal cell carcinoma that has_material_basis_in cells that appear very pale or clear when examined under microscope.", "url": "https://disease-ontology.org/term/DOID:4467", "evidence": [ { "id": "4467", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4467" } ], "weight": 0.0 }, { "disease_id": "DOID:4947", "name": "cholangiocarcinoma", "description": "A bile duct adenocarcinoma that has_material_basis_in bile duct epithelial cells.", "url": "https://disease-ontology.org/term/DOID:4947", "evidence": [ { "id": "4947", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4947" } ], "weight": 0.0 }, { "disease_id": "DOID:5082", "name": "liver cirrhosis", "description": "", "url": "https://disease-ontology.org/term/DOID:5082", "evidence": [ { "id": "5082", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5082" } ], "weight": 0.0 }, { "disease_id": "DOID:5409", "name": "lung small cell carcinoma", "description": "A lung carcinoma that has_material_basis_in primitive-appearing cells that are smaller than normal cells and is located_in the lung.", "url": "https://disease-ontology.org/term/DOID:5409", "evidence": [ { "id": "5409", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5409" } ], "weight": 0.0 }, { "disease_id": "DOID:5419", "name": "schizophrenia", "description": "A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness.", "url": "https://disease-ontology.org/term/DOID:5419", "evidence": [ { "id": "5419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5419" } ], "weight": 0.0 }, { "disease_id": "DOID:5614", "name": "eye disease", "description": "An eye and adnexa disease that is located_in the eye.", "url": "https://disease-ontology.org/term/DOID:5614", "evidence": [ { "id": "5614", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5614" } ], "weight": 0.0 }, { "disease_id": "DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia.", "url": "https://disease-ontology.org/term/DOID:5844", "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ], "weight": 0.0 }, { "disease_id": "DOID:61", "name": "mitral valve disease", "description": "", "url": "https://disease-ontology.org/term/DOID:61", "evidence": [ { "id": "61", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:61" } ], "weight": 0.0 }, { "disease_id": "DOID:6364", "name": "migraine", "description": "A brain disease that is characterized by moderate to severe headaches, nausea, extreme sensitivity to light and sound and intense unilaterial throbbing or pulsing.", "url": "https://disease-ontology.org/term/DOID:6364", "evidence": [ { "id": "6364", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6364" } ], "weight": 0.0 }, { "disease_id": "DOID:6419", "name": "tetralogy of Fallot", "description": "", "url": "https://disease-ontology.org/term/DOID:6419", "evidence": [ { "id": "6419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6419" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:7147", "name": "ankylosing spondylitis", "description": "An arthritis that results_in inflammation in the joints of the spine and pelvis. The disease has_symptom pain, has_symptom stiffness in the spine, has_symptom stiffness in the neck, has_symptom stiffness in the hips, has_symptom stiffness in the jaw and has_symptom stiffness in the rib cage.", "url": "https://disease-ontology.org/term/DOID:7147", "evidence": [ { "id": "7147", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7147" } ], "weight": 0.0 }, { "disease_id": "DOID:7148", "name": "rheumatoid arthritis", "description": "An arthritis that is an autoimmune disease which attacks healthy cells and tissue located_in joint.", "url": "https://disease-ontology.org/term/DOID:7148", "evidence": [ { "id": "7148", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7148" } ], "weight": 0.0 }, { "disease_id": "DOID:7693", "name": "abdominal aortic aneurysm", "description": "An aortic aneurysm that is located_in the abdominal aorta.", "url": "https://disease-ontology.org/term/DOID:7693", "evidence": [ { "id": "7693", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7693" } ], "weight": 0.0 }, { "disease_id": "DOID:783", "name": "end stage renal disease", "description": "A chronic kidney disease is characterized by non-functioning kidneys, as the final stage in chronic kidney disease.", "url": "https://disease-ontology.org/term/DOID:783", "evidence": [ { "id": "783", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:783" } ], "weight": 0.0 }, { "disease_id": "DOID:784", "name": "chronic kidney disease", "description": "A kidney failure that is characterized by the gradual loss of kidney function, present for a minimum of 3 months. CKD is classified based on cause, glomerular filtration rate (GFR) category (G2-G5), and albuminuria category (A1-A3).", "url": "https://disease-ontology.org/term/DOID:784", "evidence": [ { "id": "784", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:784" } ], "weight": 0.0 }, { "disease_id": "DOID:7998", "name": "hyperthyroidism", "description": "A thyroid gland disease that involves an over production of thyroid hormone.", "url": "https://disease-ontology.org/term/DOID:7998", "evidence": [ { "id": "7998", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7998" } ], "weight": 0.0 }, { "disease_id": "DOID:83", "name": "cataract", "description": "A lens disease characterized by clouding of the lens inside the eye which leads to a decrease in vision.", "url": "https://disease-ontology.org/term/DOID:83", "evidence": [ { "id": "83", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:83" } ], "weight": 0.0 }, { "disease_id": "DOID:8552", "name": "chronic myeloid leukemia", "description": "A myeloid leukemia that is characterized by over production of white blood cells.", "url": "https://disease-ontology.org/term/DOID:8552", "evidence": [ { "id": "8552", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8552" } ], "weight": 0.0 }, { "disease_id": "DOID:8736", "name": "smallpox", "description": "A viral infectious disease that results in infection located in skin, has_material_basis_in Variola virus (Orthopoxvirus variola), which is transmitted by droplets from oral, nasal or pharyngeal mucosa, transmitted by contact with the body fluids, or transmitted by fomites. The infection results in formation of lesions, first on the face, hands and forearms and later on the trunk.", "url": "https://disease-ontology.org/term/DOID:8736", "evidence": [ { "id": "8736", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8736" } ], "weight": 0.0 }, { "disease_id": "DOID:8947", "name": "diabetic retinopathy", "description": "", "url": "https://disease-ontology.org/term/DOID:8947", "evidence": [ { "id": "8947", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8947" } ], "weight": 0.0 }, { "disease_id": "DOID:9119", "name": "acute myeloid leukemia", "description": "A myeloid leukemia that is characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal blood cells.", "url": "https://disease-ontology.org/term/DOID:9119", "evidence": [ { "id": "9119", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9119" } ], "weight": 0.0 }, { "disease_id": "DOID:916", "name": "liver benign neoplasm", "description": "", "url": "https://disease-ontology.org/term/DOID:916", "evidence": [ { "id": "916", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:916" } ], "weight": 0.0 }, { "disease_id": "DOID:9279", "name": "hyperhomocysteinemia", "description": "An amino acid metabolic disorder that involves an abnormally large level of homocysteine in the blood.", "url": "https://disease-ontology.org/term/DOID:9279", "evidence": [ { "id": "9279", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9279" } ], "weight": 0.0 }, { "disease_id": "DOID:9296", "name": "cleft lip", "description": "An orofacial cleft that is characterized by a congenital defect in the upper lip where the maxillary prominence fails to merge with the merged medial nasal prominences.", "url": "https://disease-ontology.org/term/DOID:9296", "evidence": [ { "id": "9296", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9296" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 }, { "disease_id": "DOID:9406", "name": "hypopituitarism", "description": "A pituitary gland disease characterized by the decreased secretion of one or more of the eight hormones normally produced by the pituitary gland.", "url": "https://disease-ontology.org/term/DOID:9406", "evidence": [ { "id": "9406", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9406" } ], "weight": 0.0 }, { "disease_id": "DOID:9452", "name": "steatotic liver disease", "description": "A lipid storage disease characterized by the accumulation of large vacuoles of triglyceride fat in at least 5% of hepatocytes.", "url": "https://disease-ontology.org/term/DOID:9452", "evidence": [ { "id": "9452", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9452" } ], "weight": 0.0 }, { "disease_id": "DOID:9538", "name": "multiple myeloma", "description": "A myeloid neoplasm that is located_in the plasma cells in bone marrow.", "url": "https://disease-ontology.org/term/DOID:9538", "evidence": [ { "id": "9538", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9538" } ], "weight": 0.0 }, { "disease_id": "DOID:9663", "name": "aphthous stomatitis", "description": "A stomatitis characterized by the repeated formation of benign and non-contagious mouth ulcers.", "url": "https://disease-ontology.org/term/DOID:9663", "evidence": [ { "id": "9663", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9663" } ], "weight": 0.0 }, { "disease_id": "DOID:9744", "name": "type 1 diabetes mellitus", "description": "A diabetes mellitus that is characterized by destruction of pancreatic beta cells resulting in absent or extremely low insulin production.", "url": "https://disease-ontology.org/term/DOID:9744", "evidence": [ { "id": "9744", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9744" } ], "weight": 0.0 }, { "disease_id": "DOID:9849", "name": "Meniere's disease", "description": "A vestibular disease characterized by vertigo, low-pitched tinnitus and hearing loss.", "url": "https://disease-ontology.org/term/DOID:9849", "evidence": [ { "id": "9849", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9849" } ], "weight": 0.0 }, { "disease_id": "DOID:9952", "name": "acute lymphoblastic leukemia", "description": "A acute leukemia that is characterized by over production of lymphoblasts.", "url": "https://disease-ontology.org/term/DOID:9952", "evidence": [ { "id": "9952", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9952" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A4C5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A4C5" } ], "pmid": "" } ], "biological_process": [ { "name": "tetrahydrofolate interconversion", "id": "GO:0035999", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035999", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A4C5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A4C5" } ], "pmid": "" }, { "name": "methionine metabolic process", "id": "GO:0006555", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006555", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A4C5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A4C5" } ], "pmid": "" }, { "name": "response to hypoxia", "id": "GO:0001666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001666", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A4C5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A4C5" } ], "pmid": "" }, { "name": "neural tube closure", "id": "GO:0001843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001843", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A4C5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A4C5" } ], "pmid": "" }, { "name": "response to interleukin-1", "id": "GO:0070555", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070555", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A4C5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A4C5" } ], "pmid": "" }, { "name": "response to xenobiotic stimulus", "id": "GO:0009410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009410", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A4C5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A4C5" } ], "pmid": "" }, { "name": "response to amino acid", "id": "GO:0043200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043200", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A4C5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A4C5" } ], "pmid": "" }, { "name": "response to folic acid", "id": "GO:0051593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051593", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A4C5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A4C5" } ], "pmid": "" }, { "name": "tetrahydrofolate metabolic process", "id": "GO:0046653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046653", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A4C5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A4C5" } ], "pmid": "" }, { "name": "methionine biosynthetic process", "id": "GO:0009086", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009086", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A4C5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A4C5" } ], "pmid": "" }, { "name": "response to vitamin B2", "id": "GO:0033274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033274", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A4C5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A4C5" } ], "pmid": "" }, { "name": "S-adenosylmethionine metabolic process", "id": "GO:0046500", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046500", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A4C5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A4C5" } ], "pmid": "" }, { "name": "homocysteine metabolic process", "id": "GO:0050667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050667", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A4C5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A4C5" } ], "pmid": "" }, { "name": "heterochromatin organization", "id": "GO:0070828", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070828", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A4C5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A4C5" } ], "pmid": "" } ], "molecular_function": [ { "name": "methylenetetrahydrofolate reductase (NADPH) activity", "id": "GO:0106313", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106313", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A4C5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A4C5" } ], "pmid": "" }, { "name": "flavin adenine dinucleotide binding", "id": "GO:0050660", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050660", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A4C5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A4C5" } ], "pmid": "" }, { "name": "protein-containing complex binding", "id": "GO:0044877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044877", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A4C5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A4C5" } ], "pmid": "" }, { "name": "methylenetetrahydrofolate reductase [NAD(P)H] activity", "id": "GO:0004489", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004489", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A4C5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A4C5" } ], "pmid": "" }, { "name": "NADP binding", "id": "GO:0050661", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050661", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A4C5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A4C5" } ], "pmid": "" }, { "name": "modified amino acid binding", "id": "GO:0072341", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072341", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A4C5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A4C5" } ], "pmid": "" }, { "name": "FAD binding", "id": "GO:0071949", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071949", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A4C5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A4C5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6A4C5-1", "start_pos": "599", "end_pos": "599", "site_lbl": "Thr599", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 599, "start_aa": "Thr", "end_pos": 599, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr599", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6A4C5-1" }, { "uniprot_canonical_ac": "A0A8I5ZN22-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN22", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN22" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 574, "chemical_mass": 61774.0, "gene_names": "Neurl1;Neurl1a;Neurl1;Neurl", "protein_name": "E3 ubiquitin-protein ligase NEURL1", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN22", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN22" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN22", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN22" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN22", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN22" } ], "pmid": "" }, { "name": "perikaryon", "id": "GO:0043204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043204", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN22", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN22" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN22", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN22" } ], "pmid": "" }, { "name": "dendritic spine", "id": "GO:0043197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043197", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN22", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN22" } ], "pmid": "" }, { "name": "apical dendrite", "id": "GO:0097440", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097440", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN22", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN22" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of translation", "id": "GO:0006417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006417", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN22", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN22" } ], "pmid": "" }, { "name": "Notch signaling pathway", "id": "GO:0007219", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007219", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN22", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN22" } ], "pmid": "" }, { "name": "regulation of signaling", "id": "GO:0023051", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0023051", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN22", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN22" } ], "pmid": "" }, { "name": "regulation of cell communication", "id": "GO:0010646", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010646", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN22", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN22" } ], "pmid": "" }, { "name": "negative regulation of cell population proliferation", "id": "GO:0008285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008285", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN22", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN22" } ], "pmid": "" }, { "name": "positive regulation of apoptotic process", "id": "GO:0043065", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043065", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN22", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN22" } ], "pmid": "" }, { "name": "positive regulation of synapse maturation", "id": "GO:0090129", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090129", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN22", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN22" } ], "pmid": "" }, { "name": "positive regulation of filopodium assembly", "id": "GO:0051491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051491", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN22", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN22" } ], "pmid": "" }, { "name": "positive regulation of dendritic spine development", "id": "GO:0060999", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060999", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN22", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN22" } ], "pmid": "" }, { "name": "cellular response to amino acid stimulus", "id": "GO:0071230", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071230", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN22", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN22" } ], "pmid": "" }, { "name": "negative regulation of Notch signaling pathway", "id": "GO:0045746", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045746", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN22", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN22" } ], "pmid": "" }, { "name": "positive regulation of long-term neuronal synaptic plasticity", "id": "GO:0048170", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048170", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN22", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN22" } ], "pmid": "" }, { "name": "skeletal muscle tissue development", "id": "GO:0007519", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007519", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN22", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN22" } ], "pmid": "" }, { "name": "protein monoubiquitination", "id": "GO:0006513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006513", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN22", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN22" } ], "pmid": "" }, { "name": "regulation of Notch signaling pathway", "id": "GO:0008593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008593", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN22", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN22" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN22", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN22" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN22", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN22" } ], "pmid": "" }, { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN22", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN22" } ], "pmid": "" }, { "name": "translation regulator activity", "id": "GO:0045182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045182", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN22", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN22" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I5ZN22-1", "start_pos": "511", "end_pos": "511", "site_lbl": "Thr511", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 511, "start_aa": "Thr", "end_pos": 511, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr511", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I5ZN22-1" }, { "uniprot_canonical_ac": "A0A8I6A0N0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A0N0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A0N0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 525, "chemical_mass": 59137.0, "gene_names": "Cdadc1", "protein_name": "Cytidine and dCMP deaminase domain-containing protein 1", "disease": [], "molecular_function": [ { "name": "cytidine deaminase activity", "id": "GO:0004126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004126", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A0N0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A0N0" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A0N0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A0N0" } ], "pmid": "" }, { "name": "dCMP deaminase activity", "id": "GO:0004132", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004132", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A0N0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A0N0" } ], "pmid": "" }, { "name": "importin-alpha family protein binding", "id": "GO:0061676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061676", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A0N0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A0N0" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A0N0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A0N0" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A0N0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A0N0" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A0N0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A0N0" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA cytosine deamination", "id": "GO:0070383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070383", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A0N0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A0N0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6A0N0-1" }, { "uniprot_canonical_ac": "A0A8I5ZT44-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZT44", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZT44" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 257, "chemical_mass": 29352.0, "gene_names": "Tlcd3a;Fam57a;RGD1307493;Tlcd3a", "protein_name": "", "disease": [ { "disease_id": "DOID:0070515", "name": "chromosome 16p11.2 deletion syndrome, 593-kb", "description": "A chromosomal deletion syndrome characterized by language delay and mild intellectual disability that has_material_basis_in partial deletion of a contiguous 593-kb region of chromosome 16p11.2 (chr16:29.5-30.1 Mb).", "url": "https://disease-ontology.org/term/DOID:0070515", "evidence": [ { "id": "0070515", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070515" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZT44", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZT44" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZT44", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZT44" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZT44", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZT44" } ], "pmid": "" } ], "biological_process": [ { "name": "lipid homeostasis", "id": "GO:0055088", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055088", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZT44", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZT44" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZT44-1" }, { "uniprot_canonical_ac": "M0RBE8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "M0RBE8", "url": "https://www.uniprot.org/uniprotkb/M0RBE8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 504, "chemical_mass": 53247.0, "gene_names": "Was", "protein_name": "Actin nucleation-promoting factor WAS", "disease": [ { "disease_id": "DOID:0112128", "name": "X-linked severe congenital neutropenia", "description": "A severe congenital neutropenia that has_material_basis_in hemizygous activating mutation in WAS on chromosome Xp11.23.", "url": "https://disease-ontology.org/term/DOID:0112128", "evidence": [ { "id": "0112128", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112128" } ], "weight": 0.0 }, { "disease_id": "DOID:1588", "name": "thrombocytopenia", "description": "A blood platelet disease that is characterized by low a platelet count in the blood.", "url": "https://disease-ontology.org/term/DOID:1588", "evidence": [ { "id": "1588", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1588" } ], "weight": 0.0 }, { "disease_id": "DOID:2986", "name": "IgA glomerulonephritis", "description": "A glomerulonephritis characterized by build up of IgA antibody in the glomerulus.", "url": "https://disease-ontology.org/term/DOID:2986", "evidence": [ { "id": "2986", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2986" } ], "weight": 0.0 }, { "disease_id": "DOID:9169", "name": "Wiskott-Aldrich syndrome", "description": "A syndrome that is characterized by abnormal immune system function and a reduced ability to form blood clots resulting from a decrease in the number and size of blood cell fragments involved in clotting (microthrombocytopenia).", "url": "https://disease-ontology.org/term/DOID:9169", "evidence": [ { "id": "9169", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9169" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "M0RBE8", "url": "https://www.uniprot.org/uniprotkb/M0RBE8" } ], "pmid": "" }, { "name": "SH3 domain binding", "id": "GO:0017124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017124", "evidence": [ { "database": "UniProtKB", "id": "M0RBE8", "url": "https://www.uniprot.org/uniprotkb/M0RBE8" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "M0RBE8", "url": "https://www.uniprot.org/uniprotkb/M0RBE8" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "M0RBE8", "url": "https://www.uniprot.org/uniprotkb/M0RBE8" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "M0RBE8", "url": "https://www.uniprot.org/uniprotkb/M0RBE8" } ], "pmid": "" }, { "name": "phospholipase binding", "id": "GO:0043274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043274", "evidence": [ { "database": "UniProtKB", "id": "M0RBE8", "url": "https://www.uniprot.org/uniprotkb/M0RBE8" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "M0RBE8", "url": "https://www.uniprot.org/uniprotkb/M0RBE8" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "M0RBE8", "url": "https://www.uniprot.org/uniprotkb/M0RBE8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "M0RBE8", "url": "https://www.uniprot.org/uniprotkb/M0RBE8" } ], "pmid": "" }, { "name": "actin filament", "id": "GO:0005884", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005884", "evidence": [ { "database": "UniProtKB", "id": "M0RBE8", "url": "https://www.uniprot.org/uniprotkb/M0RBE8" } ], "pmid": "" }, { "name": "cell-cell junction", "id": "GO:0005911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005911", "evidence": [ { "database": "UniProtKB", "id": "M0RBE8", "url": "https://www.uniprot.org/uniprotkb/M0RBE8" } ], "pmid": "" }, { "name": "phagocytic vesicle", "id": "GO:0045335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045335", "evidence": [ { "database": "UniProtKB", "id": "M0RBE8", "url": "https://www.uniprot.org/uniprotkb/M0RBE8" } ], "pmid": "" }, { "name": "site of double-strand break", "id": "GO:0035861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035861", "evidence": [ { "database": "UniProtKB", "id": "M0RBE8", "url": "https://www.uniprot.org/uniprotkb/M0RBE8" } ], "pmid": "" }, { "name": "vesicle membrane", "id": "GO:0012506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012506", "evidence": [ { "database": "UniProtKB", "id": "M0RBE8", "url": "https://www.uniprot.org/uniprotkb/M0RBE8" } ], "pmid": "" } ], "biological_process": [ { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "M0RBE8", "url": "https://www.uniprot.org/uniprotkb/M0RBE8" } ], "pmid": "" }, { "name": "regulation of actin polymerization or depolymerization", "id": "GO:0008064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008064", "evidence": [ { "database": "UniProtKB", "id": "M0RBE8", "url": "https://www.uniprot.org/uniprotkb/M0RBE8" } ], "pmid": "" }, { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "M0RBE8", "url": "https://www.uniprot.org/uniprotkb/M0RBE8" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "M0RBE8", "url": "https://www.uniprot.org/uniprotkb/M0RBE8" } ], "pmid": "" }, { "name": "T cell activation", "id": "GO:0042110", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042110", "evidence": [ { "database": "UniProtKB", "id": "M0RBE8", "url": "https://www.uniprot.org/uniprotkb/M0RBE8" } ], "pmid": "" }, { "name": "actin polymerization or depolymerization", "id": "GO:0008154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008154", "evidence": [ { "database": "UniProtKB", "id": "M0RBE8", "url": "https://www.uniprot.org/uniprotkb/M0RBE8" } ], "pmid": "" }, { "name": "actin filament-based movement", "id": "GO:0030048", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030048", "evidence": [ { "database": "UniProtKB", "id": "M0RBE8", "url": "https://www.uniprot.org/uniprotkb/M0RBE8" } ], "pmid": "" }, { "name": "endosomal transport", "id": "GO:0016197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016197", "evidence": [ { "database": "UniProtKB", "id": "M0RBE8", "url": "https://www.uniprot.org/uniprotkb/M0RBE8" } ], "pmid": "" }, { "name": "actin filament polymerization", "id": "GO:0030041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030041", "evidence": [ { "database": "UniProtKB", "id": "M0RBE8", "url": "https://www.uniprot.org/uniprotkb/M0RBE8" } ], "pmid": "" }, { "name": "regulation of stress fiber assembly", "id": "GO:0051492", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051492", "evidence": [ { "database": "UniProtKB", "id": "M0RBE8", "url": "https://www.uniprot.org/uniprotkb/M0RBE8" } ], "pmid": "" }, { "name": "cellular response to type II interferon", "id": "GO:0071346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071346", "evidence": [ { "database": "UniProtKB", "id": "M0RBE8", "url": "https://www.uniprot.org/uniprotkb/M0RBE8" } ], "pmid": "" }, { "name": "negative regulation of cell motility", "id": "GO:2000146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000146", "evidence": [ { "database": "UniProtKB", "id": "M0RBE8", "url": "https://www.uniprot.org/uniprotkb/M0RBE8" } ], "pmid": "" }, { "name": "negative regulation of stress fiber assembly", "id": "GO:0051497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051497", "evidence": [ { "database": "UniProtKB", "id": "M0RBE8", "url": "https://www.uniprot.org/uniprotkb/M0RBE8" } ], "pmid": "" }, { "name": "regulation of lamellipodium assembly", "id": "GO:0010591", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010591", "evidence": [ { "database": "UniProtKB", "id": "M0RBE8", "url": "https://www.uniprot.org/uniprotkb/M0RBE8" } ], "pmid": "" }, { "name": "Cdc42 protein signal transduction", "id": "GO:0032488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032488", "evidence": [ { "database": "UniProtKB", "id": "M0RBE8", "url": "https://www.uniprot.org/uniprotkb/M0RBE8" } ], "pmid": "" }, { "name": "positive regulation of double-strand break repair via homologous recombination", "id": "GO:1905168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905168", "evidence": [ { "database": "UniProtKB", "id": "M0RBE8", "url": "https://www.uniprot.org/uniprotkb/M0RBE8" } ], "pmid": "" }, { "name": "regulation of T cell antigen processing and presentation", "id": "GO:0002625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002625", "evidence": [ { "database": "UniProtKB", "id": "M0RBE8", "url": "https://www.uniprot.org/uniprotkb/M0RBE8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M0RBE8-1", "start_pos": "224", "end_pos": "224", "site_lbl": "Thr224", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 224, "start_aa": "Thr", "end_pos": 224, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr224", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "M0RBE8-1", "start_pos": "355", "end_pos": "355", "site_lbl": "Thr355", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 355, "start_aa": "Thr", "end_pos": 355, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr355", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "M0RBE8-1", "start_pos": "420", "end_pos": "420", "site_lbl": "Thr420", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 420, "start_aa": "Thr", "end_pos": 420, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr420", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "M0RBE8-1" }, { "uniprot_canonical_ac": "F1M4W7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1M4W7", "url": "https://www.uniprot.org/uniprotkb/F1M4W7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 717, "chemical_mass": 82877.0, "gene_names": "Cstf3", "protein_name": "Cleavage stimulation factor subunit 3", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1M4W7", "url": "https://www.uniprot.org/uniprotkb/F1M4W7" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1M4W7", "url": "https://www.uniprot.org/uniprotkb/F1M4W7" } ], "pmid": "" }, { "name": "mRNA cleavage stimulating factor complex", "id": "GO:0005848", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005848", "evidence": [ { "database": "UniProtKB", "id": "F1M4W7", "url": "https://www.uniprot.org/uniprotkb/F1M4W7" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA 3'-end processing", "id": "GO:0031124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031124", "evidence": [ { "database": "UniProtKB", "id": "F1M4W7", "url": "https://www.uniprot.org/uniprotkb/F1M4W7" } ], "pmid": "" }, { "name": "RNA 3'-end processing", "id": "GO:0031123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031123", "evidence": [ { "database": "UniProtKB", "id": "F1M4W7", "url": "https://www.uniprot.org/uniprotkb/F1M4W7" } ], "pmid": "" }, { "name": "regulation of mRNA 3'-end processing", "id": "GO:0031440", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031440", "evidence": [ { "database": "UniProtKB", "id": "F1M4W7", "url": "https://www.uniprot.org/uniprotkb/F1M4W7" } ], "pmid": "" }, { "name": "co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway", "id": "GO:0180010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0180010", "evidence": [ { "database": "UniProtKB", "id": "F1M4W7", "url": "https://www.uniprot.org/uniprotkb/F1M4W7" } ], "pmid": "" } ], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "F1M4W7", "url": "https://www.uniprot.org/uniprotkb/F1M4W7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "F1M4W7-1", "start_pos": "414", "end_pos": "414", "site_lbl": "Thr414", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 414, "start_aa": "Thr", "end_pos": 414, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr414", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "F1M4W7-1" }, { "uniprot_canonical_ac": "F1MA92-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1MA92", "url": "https://www.uniprot.org/uniprotkb/F1MA92" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 536, "chemical_mass": 61227.0, "gene_names": "Pld5;Pld5;RGD1562609", "protein_name": "", "disease": [], "molecular_function": [ { "name": "hydrolase activity, acting on ester bonds", "id": "GO:0016788", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016788", "evidence": [ { "database": "UniProtKB", "id": "F1MA92", "url": "https://www.uniprot.org/uniprotkb/F1MA92" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1MA92-1" }, { "uniprot_canonical_ac": "F1M332-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1M332", "url": "https://www.uniprot.org/uniprotkb/F1M332" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 812, "chemical_mass": 90895.0, "gene_names": "Arhgap28", "protein_name": "", "disease": [ { "disease_id": "DOID:1205", "name": "allergic disease", "description": "An immune system disease that is an exaggerated immune response to allergens, such as insect venom, dust mites, pollen, pet dander, drugs or some foods.", "url": "https://disease-ontology.org/term/DOID:1205", "evidence": [ { "id": "1205", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1205" } ], "weight": 0.0 }, { "disease_id": "DOID:3565", "name": "meningioma", "description": "A central nervous system cancer that are manifested in the central nervous system and arise from the arachnoid cap cells of the arachnoid villi in the meninges.", "url": "https://disease-ontology.org/term/DOID:3565", "evidence": [ { "id": "3565", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3565" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "F1M332", "url": "https://www.uniprot.org/uniprotkb/F1M332" } ], "pmid": "" } ], "biological_process": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "F1M332", "url": "https://www.uniprot.org/uniprotkb/F1M332" } ], "pmid": "" }, { "name": "regulation of small GTPase mediated signal transduction", "id": "GO:0051056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051056", "evidence": [ { "database": "UniProtKB", "id": "F1M332", "url": "https://www.uniprot.org/uniprotkb/F1M332" } ], "pmid": "" }, { "name": "negative regulation of stress fiber assembly", "id": "GO:0051497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051497", "evidence": [ { "database": "UniProtKB", "id": "F1M332", "url": "https://www.uniprot.org/uniprotkb/F1M332" } ], "pmid": "" }, { "name": "regulation of actin filament polymerization", "id": "GO:0030833", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030833", "evidence": [ { "database": "UniProtKB", "id": "F1M332", "url": "https://www.uniprot.org/uniprotkb/F1M332" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1M332", "url": "https://www.uniprot.org/uniprotkb/F1M332" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1M332-1" }, { "uniprot_canonical_ac": "F1LR36-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1LR36", "url": "https://www.uniprot.org/uniprotkb/F1LR36" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1726, "chemical_mass": 199017.0, "gene_names": "Supt6h;Supt6h", "protein_name": "Transcription elongation factor SPT6", "disease": [], "biological_process": [ { "name": "nucleosome organization", "id": "GO:0034728", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034728", "evidence": [ { "database": "UniProtKB", "id": "F1LR36", "url": "https://www.uniprot.org/uniprotkb/F1LR36" } ], "pmid": "" }, { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "F1LR36", "url": "https://www.uniprot.org/uniprotkb/F1LR36" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "F1LR36", "url": "https://www.uniprot.org/uniprotkb/F1LR36" } ], "pmid": "" }, { "name": "transcription elongation by RNA polymerase II", "id": "GO:0006368", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006368", "evidence": [ { "database": "UniProtKB", "id": "F1LR36", "url": "https://www.uniprot.org/uniprotkb/F1LR36" } ], "pmid": "" }, { "name": "mRNA transport", "id": "GO:0051028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051028", "evidence": [ { "database": "UniProtKB", "id": "F1LR36", "url": "https://www.uniprot.org/uniprotkb/F1LR36" } ], "pmid": "" }, { "name": "transcription elongation-coupled chromatin remodeling", "id": "GO:0140673", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140673", "evidence": [ { "database": "UniProtKB", "id": "F1LR36", "url": "https://www.uniprot.org/uniprotkb/F1LR36" } ], "pmid": "" }, { "name": "regulation of isotype switching", "id": "GO:0045191", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045191", "evidence": [ { "database": "UniProtKB", "id": "F1LR36", "url": "https://www.uniprot.org/uniprotkb/F1LR36" } ], "pmid": "" }, { "name": "regulation of muscle cell differentiation", "id": "GO:0051147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051147", "evidence": [ { "database": "UniProtKB", "id": "F1LR36", "url": "https://www.uniprot.org/uniprotkb/F1LR36" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "F1LR36", "url": "https://www.uniprot.org/uniprotkb/F1LR36" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "F1LR36", "url": "https://www.uniprot.org/uniprotkb/F1LR36" } ], "pmid": "" }, { "name": "nucleosome binding", "id": "GO:0031491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031491", "evidence": [ { "database": "UniProtKB", "id": "F1LR36", "url": "https://www.uniprot.org/uniprotkb/F1LR36" } ], "pmid": "" } ], "cellular_component": [ { "name": "transcription elongation factor complex", "id": "GO:0008023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008023", "evidence": [ { "database": "UniProtKB", "id": "F1LR36", "url": "https://www.uniprot.org/uniprotkb/F1LR36" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1LR36", "url": "https://www.uniprot.org/uniprotkb/F1LR36" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "F1LR36-1", "start_pos": "1539", "end_pos": "1539", "site_lbl": "Thr1539", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1539, "start_aa": "Thr", "end_pos": 1539, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1539", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "F1LR36-1", "start_pos": "1580", "end_pos": "1580", "site_lbl": "Thr1580", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1580, "start_aa": "Thr", "end_pos": 1580, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1580", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "F1LR36-1", "start_pos": "1606", "end_pos": "1606", "site_lbl": "Thr1606", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1606, "start_aa": "Thr", "end_pos": 1606, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1606", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "F1LR36-1" }, { "uniprot_canonical_ac": "M0R829-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "M0R829", "url": "https://www.uniprot.org/uniprotkb/M0R829" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1038, "chemical_mass": 119435.0, "gene_names": "Myo1h;AABR07036550.1;Myo1h", "protein_name": "", "disease": [ { "disease_id": "DOID:0060731", "name": "congenital central hypoventilation syndrome", "description": "An autonomic nervous system disease characterized by reduced responsiveness of the respiratory center to carbon dioxide, diminished pupillary light responses, and other symptoms related to defects in the autonomic nervous system and that has_material_basis_in most commonly heterozygous mutation in the PHOX2B gene on chromosome 4p13 and less frequently mutations in the RET, GDNF, EDN3, BDNF, or ASCL1 genes.", "url": "https://disease-ontology.org/term/DOID:0060731", "evidence": [ { "id": "0060731", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060731" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "M0R829", "url": "https://www.uniprot.org/uniprotkb/M0R829" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "M0R829", "url": "https://www.uniprot.org/uniprotkb/M0R829" } ], "pmid": "" }, { "name": "cytoskeletal motor activity", "id": "GO:0003774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003774", "evidence": [ { "database": "UniProtKB", "id": "M0R829", "url": "https://www.uniprot.org/uniprotkb/M0R829" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "M0R829", "url": "https://www.uniprot.org/uniprotkb/M0R829" } ], "pmid": "" }, { "name": "microfilament motor activity", "id": "GO:0000146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000146", "evidence": [ { "database": "UniProtKB", "id": "M0R829", "url": "https://www.uniprot.org/uniprotkb/M0R829" } ], "pmid": "" } ], "cellular_component": [ { "name": "myosin complex", "id": "GO:0016459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016459", "evidence": [ { "database": "UniProtKB", "id": "M0R829", "url": "https://www.uniprot.org/uniprotkb/M0R829" } ], "pmid": "" }, { "name": "cluster of actin-based cell projections", "id": "GO:0098862", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098862", "evidence": [ { "database": "UniProtKB", "id": "M0R829", "url": "https://www.uniprot.org/uniprotkb/M0R829" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "M0R829", "url": "https://www.uniprot.org/uniprotkb/M0R829" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "M0R829", "url": "https://www.uniprot.org/uniprotkb/M0R829" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "M0R829", "url": "https://www.uniprot.org/uniprotkb/M0R829" } ], "pmid": "" }, { "name": "microvillus", "id": "GO:0005902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005902", "evidence": [ { "database": "UniProtKB", "id": "M0R829", "url": "https://www.uniprot.org/uniprotkb/M0R829" } ], "pmid": "" } ], "biological_process": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "M0R829", "url": "https://www.uniprot.org/uniprotkb/M0R829" } ], "pmid": "" }, { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "M0R829", "url": "https://www.uniprot.org/uniprotkb/M0R829" } ], "pmid": "" }, { "name": "actin filament-based movement", "id": "GO:0030048", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030048", "evidence": [ { "database": "UniProtKB", "id": "M0R829", "url": "https://www.uniprot.org/uniprotkb/M0R829" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M0R829-1" }, { "uniprot_canonical_ac": "F1LNQ2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1LNQ2", "url": "https://www.uniprot.org/uniprotkb/F1LNQ2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1300, "chemical_mass": 143008.0, "gene_names": "Ambra1;Ambra1;Nyw1", "protein_name": "Activating molecule in BECN1-regulated autophagy protein 1", "disease": [ { "disease_id": "DOID:4752", "name": "multiple system atrophy", "description": "", "url": "https://disease-ontology.org/term/DOID:4752", "evidence": [ { "id": "4752", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4752" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1LNQ2", "url": "https://www.uniprot.org/uniprotkb/F1LNQ2" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "F1LNQ2", "url": "https://www.uniprot.org/uniprotkb/F1LNQ2" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "F1LNQ2", "url": "https://www.uniprot.org/uniprotkb/F1LNQ2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1LNQ2", "url": "https://www.uniprot.org/uniprotkb/F1LNQ2" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "F1LNQ2", "url": "https://www.uniprot.org/uniprotkb/F1LNQ2" } ], "pmid": "" }, { "name": "focal adhesion", "id": "GO:0005925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005925", "evidence": [ { "database": "UniProtKB", "id": "F1LNQ2", "url": "https://www.uniprot.org/uniprotkb/F1LNQ2" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "F1LNQ2", "url": "https://www.uniprot.org/uniprotkb/F1LNQ2" } ], "pmid": "" }, { "name": "autophagosome", "id": "GO:0005776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005776", "evidence": [ { "database": "UniProtKB", "id": "F1LNQ2", "url": "https://www.uniprot.org/uniprotkb/F1LNQ2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1LNQ2", "url": "https://www.uniprot.org/uniprotkb/F1LNQ2" } ], "pmid": "" }, { "name": "phagocytic vesicle", "id": "GO:0045335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045335", "evidence": [ { "database": "UniProtKB", "id": "F1LNQ2", "url": "https://www.uniprot.org/uniprotkb/F1LNQ2" } ], "pmid": "" }, { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "F1LNQ2", "url": "https://www.uniprot.org/uniprotkb/F1LNQ2" } ], "pmid": "" }, { "name": "Cul4-RING E3 ubiquitin ligase complex", "id": "GO:0080008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0080008", "evidence": [ { "database": "UniProtKB", "id": "F1LNQ2", "url": "https://www.uniprot.org/uniprotkb/F1LNQ2" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1LNQ2", "url": "https://www.uniprot.org/uniprotkb/F1LNQ2" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "F1LNQ2", "url": "https://www.uniprot.org/uniprotkb/F1LNQ2" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "F1LNQ2", "url": "https://www.uniprot.org/uniprotkb/F1LNQ2" } ], "pmid": "" }, { "name": "autophagy", "id": "GO:0006914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006914", "evidence": [ { "database": "UniProtKB", "id": "F1LNQ2", "url": "https://www.uniprot.org/uniprotkb/F1LNQ2" } ], "pmid": "" }, { "name": "positive regulation of autophagy", "id": "GO:0010508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010508", "evidence": [ { "database": "UniProtKB", "id": "F1LNQ2", "url": "https://www.uniprot.org/uniprotkb/F1LNQ2" } ], "pmid": "" }, { "name": "positive regulation of regulatory T cell differentiation", "id": "GO:0045591", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045591", "evidence": [ { "database": "UniProtKB", "id": "F1LNQ2", "url": "https://www.uniprot.org/uniprotkb/F1LNQ2" } ], "pmid": "" }, { "name": "positive regulation of mitophagy", "id": "GO:1901526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901526", "evidence": [ { "database": "UniProtKB", "id": "F1LNQ2", "url": "https://www.uniprot.org/uniprotkb/F1LNQ2" } ], "pmid": "" }, { "name": "autophagosome assembly", "id": "GO:0000045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000045", "evidence": [ { "database": "UniProtKB", "id": "F1LNQ2", "url": "https://www.uniprot.org/uniprotkb/F1LNQ2" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "F1LNQ2", "url": "https://www.uniprot.org/uniprotkb/F1LNQ2" } ], "pmid": "" }, { "name": "negative regulation of cell population proliferation", "id": "GO:0008285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008285", "evidence": [ { "database": "UniProtKB", "id": "F1LNQ2", "url": "https://www.uniprot.org/uniprotkb/F1LNQ2" } ], "pmid": "" }, { "name": "positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction", "id": "GO:0051897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051897", "evidence": [ { "database": "UniProtKB", "id": "F1LNQ2", "url": "https://www.uniprot.org/uniprotkb/F1LNQ2" } ], "pmid": "" }, { "name": "response to nutrient levels", "id": "GO:0031667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031667", "evidence": [ { "database": "UniProtKB", "id": "F1LNQ2", "url": "https://www.uniprot.org/uniprotkb/F1LNQ2" } ], "pmid": "" }, { "name": "negative regulation of neuron apoptotic process", "id": "GO:0043524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043524", "evidence": [ { "database": "UniProtKB", "id": "F1LNQ2", "url": "https://www.uniprot.org/uniprotkb/F1LNQ2" } ], "pmid": "" }, { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "F1LNQ2", "url": "https://www.uniprot.org/uniprotkb/F1LNQ2" } ], "pmid": "" }, { "name": "neural tube development", "id": "GO:0021915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021915", "evidence": [ { "database": "UniProtKB", "id": "F1LNQ2", "url": "https://www.uniprot.org/uniprotkb/F1LNQ2" } ], "pmid": "" }, { "name": "protein polyubiquitination", "id": "GO:0000209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000209", "evidence": [ { "database": "UniProtKB", "id": "F1LNQ2", "url": "https://www.uniprot.org/uniprotkb/F1LNQ2" } ], "pmid": "" }, { "name": "cellular response to starvation", "id": "GO:0009267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009267", "evidence": [ { "database": "UniProtKB", "id": "F1LNQ2", "url": "https://www.uniprot.org/uniprotkb/F1LNQ2" } ], "pmid": "" }, { "name": "mitophagy", "id": "GO:0000423", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000423", "evidence": [ { "database": "UniProtKB", "id": "F1LNQ2", "url": "https://www.uniprot.org/uniprotkb/F1LNQ2" } ], "pmid": "" }, { "name": "negative regulation of cardiac muscle cell apoptotic process", "id": "GO:0010667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010667", "evidence": [ { "database": "UniProtKB", "id": "F1LNQ2", "url": "https://www.uniprot.org/uniprotkb/F1LNQ2" } ], "pmid": "" }, { "name": "response to mitochondrial depolarisation", "id": "GO:0098780", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098780", "evidence": [ { "database": "UniProtKB", "id": "F1LNQ2", "url": "https://www.uniprot.org/uniprotkb/F1LNQ2" } ], "pmid": "" }, { "name": "positive regulation of free ubiquitin chain polymerization", "id": "GO:1904544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904544", "evidence": [ { "database": "UniProtKB", "id": "F1LNQ2", "url": "https://www.uniprot.org/uniprotkb/F1LNQ2" } ], "pmid": "" }, { "name": "regulation of G1/S transition of mitotic cell cycle", "id": "GO:2000045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000045", "evidence": [ { "database": "UniProtKB", "id": "F1LNQ2", "url": "https://www.uniprot.org/uniprotkb/F1LNQ2" } ], "pmid": "" } ], "molecular_function": [ { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "F1LNQ2", "url": "https://www.uniprot.org/uniprotkb/F1LNQ2" } ], "pmid": "" }, { "name": "GTPase binding", "id": "GO:0051020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051020", "evidence": [ { "database": "UniProtKB", "id": "F1LNQ2", "url": "https://www.uniprot.org/uniprotkb/F1LNQ2" } ], "pmid": "" }, { "name": "protein phosphatase binding", "id": "GO:0019903", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019903", "evidence": [ { "database": "UniProtKB", "id": "F1LNQ2", "url": "https://www.uniprot.org/uniprotkb/F1LNQ2" } ], "pmid": "" }, { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "F1LNQ2", "url": "https://www.uniprot.org/uniprotkb/F1LNQ2" } ], "pmid": "" }, { "name": "protein phosphatase activator activity", "id": "GO:0072542", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072542", "evidence": [ { "database": "UniProtKB", "id": "F1LNQ2", "url": "https://www.uniprot.org/uniprotkb/F1LNQ2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "F1LNQ2-1", "start_pos": "267", "end_pos": "267", "site_lbl": "Thr267", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 267, "start_aa": "Thr", "end_pos": 267, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr267", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "F1LNQ2-1" }, { "uniprot_canonical_ac": "F1M8D7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1M8D7", "url": "https://www.uniprot.org/uniprotkb/F1M8D7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 2221, "chemical_mass": 247873.0, "gene_names": "Ints1;Ints1", "protein_name": "", "disease": [ { "disease_id": "DOID:0070346", "name": "neurodevelopmental disorder with cataracts, poor growth, and dysmorphic facies", "description": "A syndrome that is characterized by impaired intellectual development with absent language and short stature and that has_material_basis_in homozygous mutation in the INTS1 gene on chromosome 7p22.", "url": "https://disease-ontology.org/term/DOID:0070346", "evidence": [ { "id": "0070346", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070346" } ], "weight": 0.0 }, { "disease_id": "DOID:83", "name": "cataract", "description": "A lens disease characterized by clouding of the lens inside the eye which leads to a decrease in vision.", "url": "https://disease-ontology.org/term/DOID:83", "evidence": [ { "id": "83", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:83" } ], "weight": 0.0 } ], "biological_process": [ { "name": "U2 snRNA 3'-end processing", "id": "GO:0034474", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034474", "evidence": [ { "database": "UniProtKB", "id": "F1M8D7", "url": "https://www.uniprot.org/uniprotkb/F1M8D7" } ], "pmid": "" }, { "name": "regulation of transcription elongation by RNA polymerase II", "id": "GO:0034243", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034243", "evidence": [ { "database": "UniProtKB", "id": "F1M8D7", "url": "https://www.uniprot.org/uniprotkb/F1M8D7" } ], "pmid": "" }, { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "F1M8D7", "url": "https://www.uniprot.org/uniprotkb/F1M8D7" } ], "pmid": "" }, { "name": "embryo implantation", "id": "GO:0007566", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007566", "evidence": [ { "database": "UniProtKB", "id": "F1M8D7", "url": "https://www.uniprot.org/uniprotkb/F1M8D7" } ], "pmid": "" }, { "name": "snRNA processing", "id": "GO:0016180", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016180", "evidence": [ { "database": "UniProtKB", "id": "F1M8D7", "url": "https://www.uniprot.org/uniprotkb/F1M8D7" } ], "pmid": "" }, { "name": "blastocyst growth", "id": "GO:0001832", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001832", "evidence": [ { "database": "UniProtKB", "id": "F1M8D7", "url": "https://www.uniprot.org/uniprotkb/F1M8D7" } ], "pmid": "" }, { "name": "inner cell mass cell proliferation", "id": "GO:0001833", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001833", "evidence": [ { "database": "UniProtKB", "id": "F1M8D7", "url": "https://www.uniprot.org/uniprotkb/F1M8D7" } ], "pmid": "" }, { "name": "RNA polymerase II transcription initiation surveillance", "id": "GO:0160240", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160240", "evidence": [ { "database": "UniProtKB", "id": "F1M8D7", "url": "https://www.uniprot.org/uniprotkb/F1M8D7" } ], "pmid": "" } ], "cellular_component": [ { "name": "integrator complex", "id": "GO:0032039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032039", "evidence": [ { "database": "UniProtKB", "id": "F1M8D7", "url": "https://www.uniprot.org/uniprotkb/F1M8D7" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1M8D7", "url": "https://www.uniprot.org/uniprotkb/F1M8D7" } ], "pmid": "" }, { "name": "INTAC complex", "id": "GO:0160232", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160232", "evidence": [ { "database": "UniProtKB", "id": "F1M8D7", "url": "https://www.uniprot.org/uniprotkb/F1M8D7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1M8D7-1" }, { "uniprot_canonical_ac": "F1LMK2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1LMK2", "url": "https://www.uniprot.org/uniprotkb/F1LMK2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 628, "chemical_mass": 71602.0, "gene_names": "Trim41;Trim41", "protein_name": "E3 ubiquitin-protein ligase TRIM41", "disease": [], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1LMK2", "url": "https://www.uniprot.org/uniprotkb/F1LMK2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1LMK2", "url": "https://www.uniprot.org/uniprotkb/F1LMK2" } ], "pmid": "" }, { "name": "fibrillar center", "id": "GO:0001650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001650", "evidence": [ { "database": "UniProtKB", "id": "F1LMK2", "url": "https://www.uniprot.org/uniprotkb/F1LMK2" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1LMK2", "url": "https://www.uniprot.org/uniprotkb/F1LMK2" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "F1LMK2", "url": "https://www.uniprot.org/uniprotkb/F1LMK2" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "F1LMK2", "url": "https://www.uniprot.org/uniprotkb/F1LMK2" } ], "pmid": "" } ], "biological_process": [ { "name": "defense response to virus", "id": "GO:0051607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051607", "evidence": [ { "database": "UniProtKB", "id": "F1LMK2", "url": "https://www.uniprot.org/uniprotkb/F1LMK2" } ], "pmid": "" }, { "name": "cellular response to lipopolysaccharide", "id": "GO:0071222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071222", "evidence": [ { "database": "UniProtKB", "id": "F1LMK2", "url": "https://www.uniprot.org/uniprotkb/F1LMK2" } ], "pmid": "" }, { "name": "cellular response to muramyl dipeptide", "id": "GO:0071225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071225", "evidence": [ { "database": "UniProtKB", "id": "F1LMK2", "url": "https://www.uniprot.org/uniprotkb/F1LMK2" } ], "pmid": "" }, { "name": "positive regulation of type I interferon-mediated signaling pathway", "id": "GO:0060340", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060340", "evidence": [ { "database": "UniProtKB", "id": "F1LMK2", "url": "https://www.uniprot.org/uniprotkb/F1LMK2" } ], "pmid": "" }, { "name": "protein monoubiquitination", "id": "GO:0006513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006513", "evidence": [ { "database": "UniProtKB", "id": "F1LMK2", "url": "https://www.uniprot.org/uniprotkb/F1LMK2" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "F1LMK2", "url": "https://www.uniprot.org/uniprotkb/F1LMK2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "F1LMK2-1", "start_pos": "212", "end_pos": "212", "site_lbl": "Thr212", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 212, "start_aa": "Thr", "end_pos": 212, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr212", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "F1LMK2-1" }, { "uniprot_canonical_ac": "F1LN08-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1LN08", "url": "https://www.uniprot.org/uniprotkb/F1LN08" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 609, "chemical_mass": 66839.0, "gene_names": "Zfp276;Zfp276", "protein_name": "Zinc finger protein 276", "disease": [], "molecular_function": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "F1LN08", "url": "https://www.uniprot.org/uniprotkb/F1LN08" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1LN08", "url": "https://www.uniprot.org/uniprotkb/F1LN08" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "F1LN08", "url": "https://www.uniprot.org/uniprotkb/F1LN08" } ], "pmid": "" }, { "name": "sequence-specific double-stranded DNA binding", "id": "GO:1990837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990837", "evidence": [ { "database": "UniProtKB", "id": "F1LN08", "url": "https://www.uniprot.org/uniprotkb/F1LN08" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1LN08", "url": "https://www.uniprot.org/uniprotkb/F1LN08" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "F1LN08", "url": "https://www.uniprot.org/uniprotkb/F1LN08" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1LN08", "url": "https://www.uniprot.org/uniprotkb/F1LN08" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "F1LN08", "url": "https://www.uniprot.org/uniprotkb/F1LN08" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1LN08-1" }, { "uniprot_canonical_ac": "F1LPW6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1LPW6", "url": "https://www.uniprot.org/uniprotkb/F1LPW6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 320, "chemical_mass": 36795.0, "gene_names": "Spin2bl1;RGD1565862;Spin2bl1", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1LPW6", "url": "https://www.uniprot.org/uniprotkb/F1LPW6" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1LPW6", "url": "https://www.uniprot.org/uniprotkb/F1LPW6" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "F1LPW6", "url": "https://www.uniprot.org/uniprotkb/F1LPW6" } ], "pmid": "" }, { "name": "gamete generation", "id": "GO:0007276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007276", "evidence": [ { "database": "UniProtKB", "id": "F1LPW6", "url": "https://www.uniprot.org/uniprotkb/F1LPW6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "F1LPW6-1", "start_pos": "106", "end_pos": "106", "site_lbl": "Thr106", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 106, "start_aa": "Thr", "end_pos": 106, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr106", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "F1LPW6-1" }, { "uniprot_canonical_ac": "F1LR42-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1LR42", "url": "https://www.uniprot.org/uniprotkb/F1LR42" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 711, "chemical_mass": 80376.0, "gene_names": "Rufy1;Rufy1", "protein_name": "RUN and FYVE domain-containing protein 1", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1LR42", "url": "https://www.uniprot.org/uniprotkb/F1LR42" } ], "pmid": "" }, { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "F1LR42", "url": "https://www.uniprot.org/uniprotkb/F1LR42" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1LR42", "url": "https://www.uniprot.org/uniprotkb/F1LR42" } ], "pmid": "" }, { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "F1LR42", "url": "https://www.uniprot.org/uniprotkb/F1LR42" } ], "pmid": "" } ], "biological_process": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "F1LR42", "url": "https://www.uniprot.org/uniprotkb/F1LR42" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "F1LR42", "url": "https://www.uniprot.org/uniprotkb/F1LR42" } ], "pmid": "" }, { "name": "regulation of endocytosis", "id": "GO:0030100", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030100", "evidence": [ { "database": "UniProtKB", "id": "F1LR42", "url": "https://www.uniprot.org/uniprotkb/F1LR42" } ], "pmid": "" }, { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "F1LR42", "url": "https://www.uniprot.org/uniprotkb/F1LR42" } ], "pmid": "" }, { "name": "endosomal vesicle fusion", "id": "GO:0034058", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034058", "evidence": [ { "database": "UniProtKB", "id": "F1LR42", "url": "https://www.uniprot.org/uniprotkb/F1LR42" } ], "pmid": "" }, { "name": "early endosome to Golgi transport", "id": "GO:0034498", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034498", "evidence": [ { "database": "UniProtKB", "id": "F1LR42", "url": "https://www.uniprot.org/uniprotkb/F1LR42" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1LR42", "url": "https://www.uniprot.org/uniprotkb/F1LR42" } ], "pmid": "" }, { "name": "SH3 domain binding", "id": "GO:0017124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017124", "evidence": [ { "database": "UniProtKB", "id": "F1LR42", "url": "https://www.uniprot.org/uniprotkb/F1LR42" } ], "pmid": "" }, { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "F1LR42", "url": "https://www.uniprot.org/uniprotkb/F1LR42" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "F1LR42", "url": "https://www.uniprot.org/uniprotkb/F1LR42" } ], "pmid": "" }, { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "F1LR42", "url": "https://www.uniprot.org/uniprotkb/F1LR42" } ], "pmid": "" }, { "name": "SH2 domain binding", "id": "GO:0042169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042169", "evidence": [ { "database": "UniProtKB", "id": "F1LR42", "url": "https://www.uniprot.org/uniprotkb/F1LR42" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1LR42-1" }, { "uniprot_canonical_ac": "F1LR51-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1LR51", "url": "https://www.uniprot.org/uniprotkb/F1LR51" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 642, "chemical_mass": 69209.0, "gene_names": "Msantd2", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1LR51", "url": "https://www.uniprot.org/uniprotkb/F1LR51" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "F1LR51", "url": "https://www.uniprot.org/uniprotkb/F1LR51" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1LR51-1" }, { "uniprot_canonical_ac": "F1M3J4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1M3J4", "url": "https://www.uniprot.org/uniprotkb/F1M3J4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1325, "chemical_mass": 148904.0, "gene_names": "Abcc4;Abcc4;Mrp4;RGD1565953", "protein_name": "ATP-binding cassette subfamily C member 4", "disease": [ { "disease_id": "DOID:13580", "name": "cholestasis", "description": "A bile duct disease that is characterized by where bile cannot flow from the liver to the duodenum.", "url": "https://disease-ontology.org/term/DOID:13580", "evidence": [ { "id": "13580", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13580" } ], "weight": 0.0 }, { "disease_id": "DOID:13619", "name": "extrahepatic cholestasis", "description": "A cholestasis resulting from causes located_in bile ducts outside the liver.", "url": "https://disease-ontology.org/term/DOID:13619", "evidence": [ { "id": "13619", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13619" } ], "weight": 0.0 }, { "disease_id": "DOID:1485", "name": "cystic fibrosis", "description": "A syndrome that is characterized by the buildup of thick, sticky mucus that can damage many organs.", "url": "https://disease-ontology.org/term/DOID:1485", "evidence": [ { "id": "1485", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1485" } ], "weight": 0.0 }, { "disease_id": "DOID:5426", "name": "primary ovarian insufficiency", "description": "An ovarian disease where ovaries do not produce estrogen despite high levels of circulating gonadotropins in women under 40.", "url": "https://disease-ontology.org/term/DOID:5426", "evidence": [ { "id": "5426", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5426" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "xenobiotic transmembrane transporter activity", "id": "GO:0042910", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042910", "evidence": [ { "database": "UniProtKB", "id": "F1M3J4", "url": "https://www.uniprot.org/uniprotkb/F1M3J4" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1M3J4", "url": "https://www.uniprot.org/uniprotkb/F1M3J4" } ], "pmid": "" }, { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "F1M3J4", "url": "https://www.uniprot.org/uniprotkb/F1M3J4" } ], "pmid": "" }, { "name": "ATPase-coupled transmembrane transporter activity", "id": "GO:0042626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042626", "evidence": [ { "database": "UniProtKB", "id": "F1M3J4", "url": "https://www.uniprot.org/uniprotkb/F1M3J4" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1M3J4", "url": "https://www.uniprot.org/uniprotkb/F1M3J4" } ], "pmid": "" }, { "name": "ABC-type xenobiotic transporter activity", "id": "GO:0008559", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008559", "evidence": [ { "database": "UniProtKB", "id": "F1M3J4", "url": "https://www.uniprot.org/uniprotkb/F1M3J4" } ], "pmid": "" }, { "name": "ABC-type bile acid transporter activity", "id": "GO:0015432", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015432", "evidence": [ { "database": "UniProtKB", "id": "F1M3J4", "url": "https://www.uniprot.org/uniprotkb/F1M3J4" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "F1M3J4", "url": "https://www.uniprot.org/uniprotkb/F1M3J4" } ], "pmid": "" }, { "name": "purine nucleotide transmembrane transporter activity", "id": "GO:0015216", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015216", "evidence": [ { "database": "UniProtKB", "id": "F1M3J4", "url": "https://www.uniprot.org/uniprotkb/F1M3J4" } ], "pmid": "" }, { "name": "efflux transmembrane transporter activity", "id": "GO:0015562", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015562", "evidence": [ { "database": "UniProtKB", "id": "F1M3J4", "url": "https://www.uniprot.org/uniprotkb/F1M3J4" } ], "pmid": "" }, { "name": "urate transmembrane transporter activity", "id": "GO:0015143", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015143", "evidence": [ { "database": "UniProtKB", "id": "F1M3J4", "url": "https://www.uniprot.org/uniprotkb/F1M3J4" } ], "pmid": "" }, { "name": "prostaglandin transmembrane transporter activity", "id": "GO:0015132", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015132", "evidence": [ { "database": "UniProtKB", "id": "F1M3J4", "url": "https://www.uniprot.org/uniprotkb/F1M3J4" } ], "pmid": "" }, { "name": "ABC-type glutathione S-conjugate transporter activity", "id": "GO:0015431", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015431", "evidence": [ { "database": "UniProtKB", "id": "F1M3J4", "url": "https://www.uniprot.org/uniprotkb/F1M3J4" } ], "pmid": "" }, { "name": "glutathione transmembrane transporter activity", "id": "GO:0034634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034634", "evidence": [ { "database": "UniProtKB", "id": "F1M3J4", "url": "https://www.uniprot.org/uniprotkb/F1M3J4" } ], "pmid": "" }, { "name": "ABC-type transporter activity", "id": "GO:0140359", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140359", "evidence": [ { "database": "UniProtKB", "id": "F1M3J4", "url": "https://www.uniprot.org/uniprotkb/F1M3J4" } ], "pmid": "" }, { "name": "guanine nucleotide transmembrane transporter activity", "id": "GO:0001409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001409", "evidence": [ { "database": "UniProtKB", "id": "F1M3J4", "url": "https://www.uniprot.org/uniprotkb/F1M3J4" } ], "pmid": "" }, { "name": "intracellularly ATP-gated chloride channel activity", "id": "GO:0005260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005260", "evidence": [ { "database": "UniProtKB", "id": "F1M3J4", "url": "https://www.uniprot.org/uniprotkb/F1M3J4" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1M3J4", "url": "https://www.uniprot.org/uniprotkb/F1M3J4" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1M3J4", "url": "https://www.uniprot.org/uniprotkb/F1M3J4" } ], "pmid": "" }, { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "F1M3J4", "url": "https://www.uniprot.org/uniprotkb/F1M3J4" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "F1M3J4", "url": "https://www.uniprot.org/uniprotkb/F1M3J4" } ], "pmid": "" }, { "name": "platelet dense granule membrane", "id": "GO:0031088", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031088", "evidence": [ { "database": "UniProtKB", "id": "F1M3J4", "url": "https://www.uniprot.org/uniprotkb/F1M3J4" } ], "pmid": "" }, { "name": "external side of apical plasma membrane", "id": "GO:0098591", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098591", "evidence": [ { "database": "UniProtKB", "id": "F1M3J4", "url": "https://www.uniprot.org/uniprotkb/F1M3J4" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "F1M3J4", "url": "https://www.uniprot.org/uniprotkb/F1M3J4" } ], "pmid": "" }, { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "F1M3J4", "url": "https://www.uniprot.org/uniprotkb/F1M3J4" } ], "pmid": "" }, { "name": "recycling endosome membrane", "id": "GO:0055038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055038", "evidence": [ { "database": "UniProtKB", "id": "F1M3J4", "url": "https://www.uniprot.org/uniprotkb/F1M3J4" } ], "pmid": "" }, { "name": "chloride channel complex", "id": "GO:0034707", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034707", "evidence": [ { "database": "UniProtKB", "id": "F1M3J4", "url": "https://www.uniprot.org/uniprotkb/F1M3J4" } ], "pmid": "" } ], "biological_process": [ { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "F1M3J4", "url": "https://www.uniprot.org/uniprotkb/F1M3J4" } ], "pmid": "" }, { "name": "bile acid and bile salt transport", "id": "GO:0015721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015721", "evidence": [ { "database": "UniProtKB", "id": "F1M3J4", "url": "https://www.uniprot.org/uniprotkb/F1M3J4" } ], "pmid": "" }, { "name": "positive regulation of smooth muscle cell proliferation", "id": "GO:0048661", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048661", "evidence": [ { "database": "UniProtKB", "id": "F1M3J4", "url": "https://www.uniprot.org/uniprotkb/F1M3J4" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "F1M3J4", "url": "https://www.uniprot.org/uniprotkb/F1M3J4" } ], "pmid": "" }, { "name": "response to xenobiotic stimulus", "id": "GO:0009410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009410", "evidence": [ { "database": "UniProtKB", "id": "F1M3J4", "url": "https://www.uniprot.org/uniprotkb/F1M3J4" } ], "pmid": "" }, { "name": "L-tryptophan metabolic process", "id": "GO:0006568", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006568", "evidence": [ { "database": "UniProtKB", "id": "F1M3J4", "url": "https://www.uniprot.org/uniprotkb/F1M3J4" } ], "pmid": "" }, { "name": "response to tetrachloromethane", "id": "GO:1904772", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904772", "evidence": [ { "database": "UniProtKB", "id": "F1M3J4", "url": "https://www.uniprot.org/uniprotkb/F1M3J4" } ], "pmid": "" }, { "name": "prostaglandin secretion", "id": "GO:0032310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032310", "evidence": [ { "database": "UniProtKB", "id": "F1M3J4", "url": "https://www.uniprot.org/uniprotkb/F1M3J4" } ], "pmid": "" }, { "name": "prostaglandin transport", "id": "GO:0015732", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015732", "evidence": [ { "database": "UniProtKB", "id": "F1M3J4", "url": "https://www.uniprot.org/uniprotkb/F1M3J4" } ], "pmid": "" }, { "name": "urate transport", "id": "GO:0015747", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015747", "evidence": [ { "database": "UniProtKB", "id": "F1M3J4", "url": "https://www.uniprot.org/uniprotkb/F1M3J4" } ], "pmid": "" }, { "name": "leukotriene transport", "id": "GO:0071716", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071716", "evidence": [ { "database": "UniProtKB", "id": "F1M3J4", "url": "https://www.uniprot.org/uniprotkb/F1M3J4" } ], "pmid": "" }, { "name": "export across plasma membrane", "id": "GO:0140115", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140115", "evidence": [ { "database": "UniProtKB", "id": "F1M3J4", "url": "https://www.uniprot.org/uniprotkb/F1M3J4" } ], "pmid": "" }, { "name": "cAMP transport", "id": "GO:0070730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070730", "evidence": [ { "database": "UniProtKB", "id": "F1M3J4", "url": "https://www.uniprot.org/uniprotkb/F1M3J4" } ], "pmid": "" }, { "name": "kynurenic acid metabolic process", "id": "GO:0034275", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034275", "evidence": [ { "database": "UniProtKB", "id": "F1M3J4", "url": "https://www.uniprot.org/uniprotkb/F1M3J4" } ], "pmid": "" }, { "name": "lipid transport", "id": "GO:0006869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006869", "evidence": [ { "database": "UniProtKB", "id": "F1M3J4", "url": "https://www.uniprot.org/uniprotkb/F1M3J4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "F1M3J4-1", "start_pos": "646", "end_pos": "646", "site_lbl": "Thr646", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "F1M3J4", "url": "https://www.uniprot.org/uniprotkb/F1M3J4" } ] } ] }, { "uniprot_canonical_ac": "F1M3J4-1", "start_pos": "648", "end_pos": "648", "site_lbl": "Thr648", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "F1M3J4", "url": "https://www.uniprot.org/uniprotkb/F1M3J4" } ] } ] }, { "uniprot_canonical_ac": "F1M3J4-1", "start_pos": "664", "end_pos": "664", "site_lbl": "Ser664", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "F1M3J4", "url": "https://www.uniprot.org/uniprotkb/F1M3J4" } ] } ] }, { "uniprot_canonical_ac": "F1M3J4-1", "start_pos": "668", "end_pos": "668", "site_lbl": "Ser668", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "F1M3J4", "url": "https://www.uniprot.org/uniprotkb/F1M3J4" } ] } ] } ], "record_id": "F1M3J4-1" }, { "uniprot_canonical_ac": "F1LRS5-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1LRS5", "url": "https://www.uniprot.org/uniprotkb/F1LRS5" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 652, "chemical_mass": 72534.0, "gene_names": "Aplp1", "protein_name": "Amyloid beta precursor like protein 1", "disease": [ { "disease_id": "DOID:0080348", "name": "Alzheimer's disease 1", "description": "An Alzheimer's disease that has_material_basis_in mutation heterozygous mutation in the APP gene, which encodes the amyloid precursor protein, on chromosome 21q21.", "url": "https://disease-ontology.org/term/DOID:0080348", "evidence": [ { "id": "0080348", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080348" } ], "weight": 0.0 }, { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "F1LRS5", "url": "https://www.uniprot.org/uniprotkb/F1LRS5" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1LRS5", "url": "https://www.uniprot.org/uniprotkb/F1LRS5" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1LRS5", "url": "https://www.uniprot.org/uniprotkb/F1LRS5" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "F1LRS5", "url": "https://www.uniprot.org/uniprotkb/F1LRS5" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of translation", "id": "GO:0006417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006417", "evidence": [ { "database": "UniProtKB", "id": "F1LRS5", "url": "https://www.uniprot.org/uniprotkb/F1LRS5" } ], "pmid": "" }, { "name": "extracellular matrix organization", "id": "GO:0030198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030198", "evidence": [ { "database": "UniProtKB", "id": "F1LRS5", "url": "https://www.uniprot.org/uniprotkb/F1LRS5" } ], "pmid": "" }, { "name": "forebrain development", "id": "GO:0030900", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030900", "evidence": [ { "database": "UniProtKB", "id": "F1LRS5", "url": "https://www.uniprot.org/uniprotkb/F1LRS5" } ], "pmid": "" }, { "name": "cellular response to norepinephrine stimulus", "id": "GO:0071874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071874", "evidence": [ { "database": "UniProtKB", "id": "F1LRS5", "url": "https://www.uniprot.org/uniprotkb/F1LRS5" } ], "pmid": "" }, { "name": "negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway", "id": "GO:0106072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106072", "evidence": [ { "database": "UniProtKB", "id": "F1LRS5", "url": "https://www.uniprot.org/uniprotkb/F1LRS5" } ], "pmid": "" }, { "name": "cytosolic mRNA polyadenylation", "id": "GO:0180011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0180011", "evidence": [ { "database": "UniProtKB", "id": "F1LRS5", "url": "https://www.uniprot.org/uniprotkb/F1LRS5" } ], "pmid": "" }, { "name": "axonogenesis", "id": "GO:0007409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007409", "evidence": [ { "database": "UniProtKB", "id": "F1LRS5", "url": "https://www.uniprot.org/uniprotkb/F1LRS5" } ], "pmid": "" }, { "name": "central nervous system development", "id": "GO:0007417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007417", "evidence": [ { "database": "UniProtKB", "id": "F1LRS5", "url": "https://www.uniprot.org/uniprotkb/F1LRS5" } ], "pmid": "" } ], "molecular_function": [ { "name": "heparin binding", "id": "GO:0008201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008201", "evidence": [ { "database": "UniProtKB", "id": "F1LRS5", "url": "https://www.uniprot.org/uniprotkb/F1LRS5" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "F1LRS5", "url": "https://www.uniprot.org/uniprotkb/F1LRS5" } ], "pmid": "" }, { "name": "transition metal ion binding", "id": "GO:0046914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046914", "evidence": [ { "database": "UniProtKB", "id": "F1LRS5", "url": "https://www.uniprot.org/uniprotkb/F1LRS5" } ], "pmid": "" }, { "name": "alpha-2A adrenergic receptor binding", "id": "GO:0031694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031694", "evidence": [ { "database": "UniProtKB", "id": "F1LRS5", "url": "https://www.uniprot.org/uniprotkb/F1LRS5" } ], "pmid": "" }, { "name": "alpha-2C adrenergic receptor binding", "id": "GO:0031696", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031696", "evidence": [ { "database": "UniProtKB", "id": "F1LRS5", "url": "https://www.uniprot.org/uniprotkb/F1LRS5" } ], "pmid": "" }, { "name": "alpha-2B adrenergic receptor binding", "id": "GO:0031695", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031695", "evidence": [ { "database": "UniProtKB", "id": "F1LRS5", "url": "https://www.uniprot.org/uniprotkb/F1LRS5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "F1LRS5-1", "start_pos": "215", "end_pos": "215", "site_lbl": "Thr215", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 215, "start_aa": "Thr", "end_pos": 215, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr215", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "F1LRS5-1", "start_pos": "289", "end_pos": "289", "site_lbl": "Thr289", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 289, "start_aa": "Thr", "end_pos": 289, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr289", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "F1LRS5-1", "start_pos": "291", "end_pos": "291", "site_lbl": "Thr291", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 291, "start_aa": "Thr", "end_pos": 291, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr291", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "F1LRS5-1", "start_pos": "295", "end_pos": "295", "site_lbl": "Thr295", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 295, "start_aa": "Thr", "end_pos": 295, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr295", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "F1LRS5-1" }, { "uniprot_canonical_ac": "F1LRV5-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1LRV5", "url": "https://www.uniprot.org/uniprotkb/F1LRV5" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 524, "chemical_mass": 58541.0, "gene_names": "Btn1a1;Btn1a1", "protein_name": "", "disease": [], "molecular_function": [ { "name": "signaling receptor binding", "id": "GO:0005102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005102", "evidence": [ { "database": "UniProtKB", "id": "F1LRV5", "url": "https://www.uniprot.org/uniprotkb/F1LRV5" } ], "pmid": "" } ], "cellular_component": [ { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "F1LRV5", "url": "https://www.uniprot.org/uniprotkb/F1LRV5" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1LRV5", "url": "https://www.uniprot.org/uniprotkb/F1LRV5" } ], "pmid": "" } ], "biological_process": [ { "name": "T cell receptor signaling pathway", "id": "GO:0050852", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050852", "evidence": [ { "database": "UniProtKB", "id": "F1LRV5", "url": "https://www.uniprot.org/uniprotkb/F1LRV5" } ], "pmid": "" }, { "name": "regulation of cytokine production", "id": "GO:0001817", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001817", "evidence": [ { "database": "UniProtKB", "id": "F1LRV5", "url": "https://www.uniprot.org/uniprotkb/F1LRV5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1LRV5-1" }, { "uniprot_canonical_ac": "F1LSL7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1LSL7", "url": "https://www.uniprot.org/uniprotkb/F1LSL7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 443, "chemical_mass": 49444.0, "gene_names": "Klf5;Bteb2;IKLF;Klf5;bteb2", "protein_name": "", "disease": [ { "disease_id": "DOID:0070508", "name": "metabolic dysfunction and alcohol associated liver disease", "description": "A steatotic liver disease characterized by at least one of five specified cardiometabolic risk factors and elevated alcohol consumption. This disease is distinguished from MASLD by increased alcohol consumption and from ALD by the evidence of one or more of the specified cardiometabolic risk factors. The five cardiometabolic risk factors are: (1) higher than normal body mass index or waist circumference; (2) higher than normal serum glucose or glycated hemoglobin level, or type 2 diabetes; (3) higher than normal blood pressure or hypertensive treatment; (4) higher than normal plasma triglycerides or lipid lowering treatment; and (5) lower than normal plasma high-density lipoprotein cholesterol.", "url": "https://disease-ontology.org/term/DOID:0070508", "evidence": [ { "id": "0070508", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070508" } ], "weight": 0.0 }, { "disease_id": "DOID:10941", "name": "intracranial aneurysm", "description": "", "url": "https://disease-ontology.org/term/DOID:10941", "evidence": [ { "id": "10941", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10941" } ], "weight": 0.0 }, { "disease_id": "DOID:224", "name": "transient cerebral ischemia", "description": "A brain ischemia that is characterized by ischemia of brief duration and without resultant tissue death.", "url": "https://disease-ontology.org/term/DOID:224", "evidence": [ { "id": "224", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:224" } ], "weight": 0.0 } ], "biological_process": [ { "name": "skeletal muscle tissue regeneration", "id": "GO:0043403", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043403", "evidence": [ { "database": "UniProtKB", "id": "F1LSL7", "url": "https://www.uniprot.org/uniprotkb/F1LSL7" } ], "pmid": "" }, { "name": "skeletal muscle satellite cell differentiation", "id": "GO:0014816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014816", "evidence": [ { "database": "UniProtKB", "id": "F1LSL7", "url": "https://www.uniprot.org/uniprotkb/F1LSL7" } ], "pmid": "" }, { "name": "cellular response to endothelin", "id": "GO:1990859", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990859", "evidence": [ { "database": "UniProtKB", "id": "F1LSL7", "url": "https://www.uniprot.org/uniprotkb/F1LSL7" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "F1LSL7", "url": "https://www.uniprot.org/uniprotkb/F1LSL7" } ], "pmid": "" }, { "name": "angiogenesis", "id": "GO:0001525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001525", "evidence": [ { "database": "UniProtKB", "id": "F1LSL7", "url": "https://www.uniprot.org/uniprotkb/F1LSL7" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1LSL7", "url": "https://www.uniprot.org/uniprotkb/F1LSL7" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "F1LSL7", "url": "https://www.uniprot.org/uniprotkb/F1LSL7" } ], "pmid": "" }, { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "F1LSL7", "url": "https://www.uniprot.org/uniprotkb/F1LSL7" } ], "pmid": "" }, { "name": "positive regulation of fat cell differentiation", "id": "GO:0045600", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045600", "evidence": [ { "database": "UniProtKB", "id": "F1LSL7", "url": "https://www.uniprot.org/uniprotkb/F1LSL7" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "F1LSL7", "url": "https://www.uniprot.org/uniprotkb/F1LSL7" } ], "pmid": "" }, { "name": "cellular response to leukemia inhibitory factor", "id": "GO:1990830", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990830", "evidence": [ { "database": "UniProtKB", "id": "F1LSL7", "url": "https://www.uniprot.org/uniprotkb/F1LSL7" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "F1LSL7", "url": "https://www.uniprot.org/uniprotkb/F1LSL7" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "F1LSL7", "url": "https://www.uniprot.org/uniprotkb/F1LSL7" } ], "pmid": "" }, { "name": "skeletal muscle cell differentiation", "id": "GO:0035914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035914", "evidence": [ { "database": "UniProtKB", "id": "F1LSL7", "url": "https://www.uniprot.org/uniprotkb/F1LSL7" } ], "pmid": "" }, { "name": "gene expression", "id": "GO:0010467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010467", "evidence": [ { "database": "UniProtKB", "id": "F1LSL7", "url": "https://www.uniprot.org/uniprotkb/F1LSL7" } ], "pmid": "" }, { "name": "myotube differentiation involved in skeletal muscle regeneration", "id": "GO:0014908", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014908", "evidence": [ { "database": "UniProtKB", "id": "F1LSL7", "url": "https://www.uniprot.org/uniprotkb/F1LSL7" } ], "pmid": "" }, { "name": "intestinal epithelial cell development", "id": "GO:0060576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060576", "evidence": [ { "database": "UniProtKB", "id": "F1LSL7", "url": "https://www.uniprot.org/uniprotkb/F1LSL7" } ], "pmid": "" }, { "name": "satellite cell activation involved in skeletal muscle regeneration", "id": "GO:0014901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014901", "evidence": [ { "database": "UniProtKB", "id": "F1LSL7", "url": "https://www.uniprot.org/uniprotkb/F1LSL7" } ], "pmid": "" }, { "name": "positive regulation of transcription by transcription factor localization", "id": "GO:0061586", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061586", "evidence": [ { "database": "UniProtKB", "id": "F1LSL7", "url": "https://www.uniprot.org/uniprotkb/F1LSL7" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "F1LSL7", "url": "https://www.uniprot.org/uniprotkb/F1LSL7" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "F1LSL7", "url": "https://www.uniprot.org/uniprotkb/F1LSL7" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1LSL7", "url": "https://www.uniprot.org/uniprotkb/F1LSL7" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "F1LSL7", "url": "https://www.uniprot.org/uniprotkb/F1LSL7" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "F1LSL7", "url": "https://www.uniprot.org/uniprotkb/F1LSL7" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "F1LSL7", "url": "https://www.uniprot.org/uniprotkb/F1LSL7" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "F1LSL7", "url": "https://www.uniprot.org/uniprotkb/F1LSL7" } ], "pmid": "" }, { "name": "MRF binding", "id": "GO:0043426", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043426", "evidence": [ { "database": "UniProtKB", "id": "F1LSL7", "url": "https://www.uniprot.org/uniprotkb/F1LSL7" } ], "pmid": "" }, { "name": "sequence-specific double-stranded DNA binding", "id": "GO:1990837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990837", "evidence": [ { "database": "UniProtKB", "id": "F1LSL7", "url": "https://www.uniprot.org/uniprotkb/F1LSL7" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1LSL7", "url": "https://www.uniprot.org/uniprotkb/F1LSL7" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1LSL7", "url": "https://www.uniprot.org/uniprotkb/F1LSL7" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "F1LSL7", "url": "https://www.uniprot.org/uniprotkb/F1LSL7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "F1LSL7-1", "start_pos": "173", "end_pos": "173", "site_lbl": "Thr173", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 173, "start_aa": "Thr", "end_pos": 173, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr173", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "F1LSL7-1" }, { "uniprot_canonical_ac": "F1LTR7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1LTR7", "url": "https://www.uniprot.org/uniprotkb/F1LTR7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 223, "chemical_mass": 24690.0, "gene_names": "Ncr2l1;LOC680920;Ncr2l1", "protein_name": "", "disease": [], "cellular_component": [ { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "F1LTR7", "url": "https://www.uniprot.org/uniprotkb/F1LTR7" } ], "pmid": "" } ], "molecular_function": [ { "name": "signaling receptor activity", "id": "GO:0038023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038023", "evidence": [ { "database": "UniProtKB", "id": "F1LTR7", "url": "https://www.uniprot.org/uniprotkb/F1LTR7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1LTR7-1" }, { "uniprot_canonical_ac": "F1LTU1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1LTU1", "url": "https://www.uniprot.org/uniprotkb/F1LTU1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 672, "chemical_mass": 75535.0, "gene_names": "Tspear;RGD1563108;Tspear", "protein_name": "", "disease": [ { "disease_id": "DOID:0050591", "name": "tooth agenesis", "description": "A tooth disease characterized by failure to develop one or more missing teeth.", "url": "https://disease-ontology.org/term/DOID:0050591", "evidence": [ { "id": "0050591", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050591" } ], "weight": 0.0 }, { "disease_id": "DOID:0110540", "name": "autosomal recessive nonsyndromic deafness 98", "description": "An autosomal recessive nonsyndromic deafness that has_material_basis_in mutation in the TSPEAR gene on chromosome 21q22.", "url": "https://disease-ontology.org/term/DOID:0110540", "evidence": [ { "id": "0110540", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110540" } ], "weight": 0.0 }, { "disease_id": "DOID:0111662", "name": "ectodermal dysplasia 14", "description": "An ectodermal dysplasia characterized by scalp hypotrichosis and hypodontia that has_material_basis_in homozygous or compound heterozygous mutation in the TSPEAR gene on chromosome 21q22.3.", "url": "https://disease-ontology.org/term/DOID:0111662", "evidence": [ { "id": "0111662", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111662" } ], "weight": 0.0 } ], "biological_process": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "F1LTU1", "url": "https://www.uniprot.org/uniprotkb/F1LTU1" } ], "pmid": "" }, { "name": "Notch signaling pathway", "id": "GO:0007219", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007219", "evidence": [ { "database": "UniProtKB", "id": "F1LTU1", "url": "https://www.uniprot.org/uniprotkb/F1LTU1" } ], "pmid": "" }, { "name": "sensory perception of sound", "id": "GO:0007605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007605", "evidence": [ { "database": "UniProtKB", "id": "F1LTU1", "url": "https://www.uniprot.org/uniprotkb/F1LTU1" } ], "pmid": "" }, { "name": "tooth mineralization", "id": "GO:0034505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034505", "evidence": [ { "database": "UniProtKB", "id": "F1LTU1", "url": "https://www.uniprot.org/uniprotkb/F1LTU1" } ], "pmid": "" }, { "name": "hair cycle process", "id": "GO:0022405", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022405", "evidence": [ { "database": "UniProtKB", "id": "F1LTU1", "url": "https://www.uniprot.org/uniprotkb/F1LTU1" } ], "pmid": "" }, { "name": "regulation of Notch signaling pathway", "id": "GO:0008593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008593", "evidence": [ { "database": "UniProtKB", "id": "F1LTU1", "url": "https://www.uniprot.org/uniprotkb/F1LTU1" } ], "pmid": "" } ], "cellular_component": [ { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "F1LTU1", "url": "https://www.uniprot.org/uniprotkb/F1LTU1" } ], "pmid": "" }, { "name": "ciliary membrane", "id": "GO:0060170", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060170", "evidence": [ { "database": "UniProtKB", "id": "F1LTU1", "url": "https://www.uniprot.org/uniprotkb/F1LTU1" } ], "pmid": "" }, { "name": "stereocilium", "id": "GO:0032420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032420", "evidence": [ { "database": "UniProtKB", "id": "F1LTU1", "url": "https://www.uniprot.org/uniprotkb/F1LTU1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1LTU1-1" }, { "uniprot_canonical_ac": "F1LTU7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1LTU7", "url": "https://www.uniprot.org/uniprotkb/F1LTU7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 363, "chemical_mass": 41127.0, "gene_names": "Gmnc", "protein_name": "", "disease": [], "molecular_function": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "F1LTU7", "url": "https://www.uniprot.org/uniprotkb/F1LTU7" } ], "pmid": "" }, { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "F1LTU7", "url": "https://www.uniprot.org/uniprotkb/F1LTU7" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1LTU7", "url": "https://www.uniprot.org/uniprotkb/F1LTU7" } ], "pmid": "" }, { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "F1LTU7", "url": "https://www.uniprot.org/uniprotkb/F1LTU7" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "F1LTU7", "url": "https://www.uniprot.org/uniprotkb/F1LTU7" } ], "pmid": "" }, { "name": "DNA replication", "id": "GO:0006260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006260", "evidence": [ { "database": "UniProtKB", "id": "F1LTU7", "url": "https://www.uniprot.org/uniprotkb/F1LTU7" } ], "pmid": "" }, { "name": "regulation of DNA-templated DNA replication initiation", "id": "GO:0030174", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030174", "evidence": [ { "database": "UniProtKB", "id": "F1LTU7", "url": "https://www.uniprot.org/uniprotkb/F1LTU7" } ], "pmid": "" }, { "name": "multi-ciliated epithelial cell differentiation", "id": "GO:1903251", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903251", "evidence": [ { "database": "UniProtKB", "id": "F1LTU7", "url": "https://www.uniprot.org/uniprotkb/F1LTU7" } ], "pmid": "" }, { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "F1LTU7", "url": "https://www.uniprot.org/uniprotkb/F1LTU7" } ], "pmid": "" }, { "name": "single fertilization", "id": "GO:0007338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007338", "evidence": [ { "database": "UniProtKB", "id": "F1LTU7", "url": "https://www.uniprot.org/uniprotkb/F1LTU7" } ], "pmid": "" }, { "name": "multicellular organism growth", "id": "GO:0035264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035264", "evidence": [ { "database": "UniProtKB", "id": "F1LTU7", "url": "https://www.uniprot.org/uniprotkb/F1LTU7" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "F1LTU7", "url": "https://www.uniprot.org/uniprotkb/F1LTU7" } ], "pmid": "" }, { "name": "seminiferous tubule development", "id": "GO:0072520", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072520", "evidence": [ { "database": "UniProtKB", "id": "F1LTU7", "url": "https://www.uniprot.org/uniprotkb/F1LTU7" } ], "pmid": "" }, { "name": "cerebrospinal fluid circulation", "id": "GO:0090660", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090660", "evidence": [ { "database": "UniProtKB", "id": "F1LTU7", "url": "https://www.uniprot.org/uniprotkb/F1LTU7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1LTU7-1" }, { "uniprot_canonical_ac": "F1LTX4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1LTX4", "url": "https://www.uniprot.org/uniprotkb/F1LTX4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 735, "chemical_mass": 80897.0, "gene_names": "Lrrn4;Lrrn4;RGD1305256", "protein_name": "", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1LTX4", "url": "https://www.uniprot.org/uniprotkb/F1LTX4" } ], "pmid": "" } ], "biological_process": [ { "name": "visual learning", "id": "GO:0008542", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008542", "evidence": [ { "database": "UniProtKB", "id": "F1LTX4", "url": "https://www.uniprot.org/uniprotkb/F1LTX4" } ], "pmid": "" }, { "name": "long-term memory", "id": "GO:0007616", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007616", "evidence": [ { "database": "UniProtKB", "id": "F1LTX4", "url": "https://www.uniprot.org/uniprotkb/F1LTX4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1LTX4-1" }, { "uniprot_canonical_ac": "A0A8I6A2V5-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2V5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2V5" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1165, "chemical_mass": 129769.0, "gene_names": "AABR07029605.1;Fnip1;AABR07029605.1;Fnip1", "protein_name": "", "disease": [ { "disease_id": "DOID:0061063", "name": "immunodeficiency 93", "description": "A primary immunodeficiency disease that is characterized by onset of recurrent viral and bacterial infections, particularly with encapsulated bacteria, and hypertrophic cardiomyopathy in the first months or years of life and that has_material_basis_in homozygous or compound heterozygous mutation in the FNIP1 gene on chromosome 5q31.", "url": "https://disease-ontology.org/term/DOID:0061063", "evidence": [ { "id": "0061063", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061063" } ], "weight": 0.0 } ], "biological_process": [ { "name": "immature B cell differentiation", "id": "GO:0002327", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002327", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2V5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2V5" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2V5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2V5" } ], "pmid": "" }, { "name": "negative regulation of TOR signaling", "id": "GO:0032007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032007", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2V5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2V5" } ], "pmid": "" }, { "name": "cellular response to starvation", "id": "GO:0009267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009267", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2V5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2V5" } ], "pmid": "" }, { "name": "positive regulation of B cell apoptotic process", "id": "GO:0002904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002904", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2V5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2V5" } ], "pmid": "" }, { "name": "regulation of pro-B cell differentiation", "id": "GO:2000973", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000973", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2V5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2V5" } ], "pmid": "" }, { "name": "positive regulation of TORC1 signaling", "id": "GO:1904263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904263", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2V5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2V5" } ], "pmid": "" }, { "name": "negative regulation of cell population proliferation", "id": "GO:0008285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008285", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2V5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2V5" } ], "pmid": "" }, { "name": "positive regulation of protein-containing complex assembly", "id": "GO:0031334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031334", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2V5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2V5" } ], "pmid": "" }, { "name": "B cell differentiation", "id": "GO:0030183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030183", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2V5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2V5" } ], "pmid": "" }, { "name": "positive regulation of TOR signaling", "id": "GO:0032008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032008", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2V5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2V5" } ], "pmid": "" }, { "name": "negative regulation of lysosome organization", "id": "GO:1905672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905672", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2V5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2V5" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2V5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2V5" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2V5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2V5" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2V5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2V5" } ], "pmid": "" }, { "name": "FNIP-folliculin RagC/D GAP", "id": "GO:1990877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990877", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2V5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2V5" } ], "pmid": "" } ], "molecular_function": [ { "name": "enzyme activator activity", "id": "GO:0008047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008047", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2V5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2V5" } ], "pmid": "" }, { "name": "enzyme binding", "id": "GO:0019899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019899", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2V5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2V5" } ], "pmid": "" }, { "name": "protein-folding chaperone binding", "id": "GO:0051087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051087", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2V5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2V5" } ], "pmid": "" }, { "name": "ATPase inhibitor activity", "id": "GO:0042030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042030", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2V5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2V5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6A2V5-1" }, { "uniprot_canonical_ac": "F1LUS3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1LUS3", "url": "https://www.uniprot.org/uniprotkb/F1LUS3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 453, "chemical_mass": 51875.0, "gene_names": "Mipol1", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1LUS3", "url": "https://www.uniprot.org/uniprotkb/F1LUS3" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1LUS3", "url": "https://www.uniprot.org/uniprotkb/F1LUS3" } ], "pmid": "" } ], "molecular_function": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "F1LUS3", "url": "https://www.uniprot.org/uniprotkb/F1LUS3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1LUS3-1" }, { "uniprot_canonical_ac": "F1LUT3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1LUT3", "url": "https://www.uniprot.org/uniprotkb/F1LUT3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 236, "chemical_mass": 26869.0, "gene_names": "Spin2b;Spin2b", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1LUT3", "url": "https://www.uniprot.org/uniprotkb/F1LUT3" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1LUT3", "url": "https://www.uniprot.org/uniprotkb/F1LUT3" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "F1LUT3", "url": "https://www.uniprot.org/uniprotkb/F1LUT3" } ], "pmid": "" }, { "name": "gamete generation", "id": "GO:0007276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007276", "evidence": [ { "database": "UniProtKB", "id": "F1LUT3", "url": "https://www.uniprot.org/uniprotkb/F1LUT3" } ], "pmid": "" } ], "molecular_function": [ { "name": "histone H3K4me3 reader activity", "id": "GO:0140002", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140002", "evidence": [ { "database": "UniProtKB", "id": "F1LUT3", "url": "https://www.uniprot.org/uniprotkb/F1LUT3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "F1LUT3-1", "start_pos": "22", "end_pos": "22", "site_lbl": "Thr22", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 22, "start_aa": "Thr", "end_pos": 22, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr22", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "F1LUT3-1" }, { "uniprot_canonical_ac": "F1LUV1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1LUV1", "url": "https://www.uniprot.org/uniprotkb/F1LUV1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 419, "chemical_mass": 49214.0, "gene_names": "Magec2l1;Magec2l1;RGD1561327", "protein_name": "", "disease": [], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "F1LUV1", "url": "https://www.uniprot.org/uniprotkb/F1LUV1" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1LUV1", "url": "https://www.uniprot.org/uniprotkb/F1LUV1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1LUV1-1" }, { "uniprot_canonical_ac": "F1LVC4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1LVC4", "url": "https://www.uniprot.org/uniprotkb/F1LVC4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 526, "chemical_mass": 59742.0, "gene_names": "Tigd2;RGD1559612;Tigd2", "protein_name": "", "disease": [], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "F1LVC4", "url": "https://www.uniprot.org/uniprotkb/F1LVC4" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1LVC4", "url": "https://www.uniprot.org/uniprotkb/F1LVC4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1LVC4-1" }, { "uniprot_canonical_ac": "F1LVE6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1LVE6", "url": "https://www.uniprot.org/uniprotkb/F1LVE6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 425, "chemical_mass": 46437.0, "gene_names": "Ldc1;RGD1562036", "protein_name": "Antizyme inhibitor 2", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1LVE6", "url": "https://www.uniprot.org/uniprotkb/F1LVE6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1LVE6", "url": "https://www.uniprot.org/uniprotkb/F1LVE6" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "F1LVE6", "url": "https://www.uniprot.org/uniprotkb/F1LVE6" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1LVE6", "url": "https://www.uniprot.org/uniprotkb/F1LVE6" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "F1LVE6", "url": "https://www.uniprot.org/uniprotkb/F1LVE6" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "F1LVE6", "url": "https://www.uniprot.org/uniprotkb/F1LVE6" } ], "pmid": "" }, { "name": "perikaryon", "id": "GO:0043204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043204", "evidence": [ { "database": "UniProtKB", "id": "F1LVE6", "url": "https://www.uniprot.org/uniprotkb/F1LVE6" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "F1LVE6", "url": "https://www.uniprot.org/uniprotkb/F1LVE6" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "F1LVE6", "url": "https://www.uniprot.org/uniprotkb/F1LVE6" } ], "pmid": "" }, { "name": "endoplasmic reticulum-Golgi intermediate compartment", "id": "GO:0005793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005793", "evidence": [ { "database": "UniProtKB", "id": "F1LVE6", "url": "https://www.uniprot.org/uniprotkb/F1LVE6" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of protein catabolic process", "id": "GO:0042177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042177", "evidence": [ { "database": "UniProtKB", "id": "F1LVE6", "url": "https://www.uniprot.org/uniprotkb/F1LVE6" } ], "pmid": "" }, { "name": "putrescine biosynthetic process from arginine, via ornithine", "id": "GO:0033387", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033387", "evidence": [ { "database": "UniProtKB", "id": "F1LVE6", "url": "https://www.uniprot.org/uniprotkb/F1LVE6" } ], "pmid": "" }, { "name": "positive regulation of polyamine transmembrane transport", "id": "GO:1902269", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902269", "evidence": [ { "database": "UniProtKB", "id": "F1LVE6", "url": "https://www.uniprot.org/uniprotkb/F1LVE6" } ], "pmid": "" } ], "molecular_function": [ { "name": "ornithine decarboxylase activator activity", "id": "GO:0042978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042978", "evidence": [ { "database": "UniProtKB", "id": "F1LVE6", "url": "https://www.uniprot.org/uniprotkb/F1LVE6" } ], "pmid": "" }, { "name": "carboxy-lyase activity", "id": "GO:0016831", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016831", "evidence": [ { "database": "UniProtKB", "id": "F1LVE6", "url": "https://www.uniprot.org/uniprotkb/F1LVE6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1LVE6-1" }, { "uniprot_canonical_ac": "F1LVK3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1LVK3", "url": "https://www.uniprot.org/uniprotkb/F1LVK3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 737, "chemical_mass": 80753.0, "gene_names": "Chadl;Chadl", "protein_name": "Chondroadherin-like protein", "disease": [], "cellular_component": [ { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "F1LVK3", "url": "https://www.uniprot.org/uniprotkb/F1LVK3" } ], "pmid": "" }, { "name": "gel phase of interstitial matrix", "id": "GO:0140150", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140150", "evidence": [ { "database": "UniProtKB", "id": "F1LVK3", "url": "https://www.uniprot.org/uniprotkb/F1LVK3" } ], "pmid": "" } ], "molecular_function": [ { "name": "collagen binding", "id": "GO:0005518", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005518", "evidence": [ { "database": "UniProtKB", "id": "F1LVK3", "url": "https://www.uniprot.org/uniprotkb/F1LVK3" } ], "pmid": "" }, { "name": "collagen fibril binding", "id": "GO:0098633", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098633", "evidence": [ { "database": "UniProtKB", "id": "F1LVK3", "url": "https://www.uniprot.org/uniprotkb/F1LVK3" } ], "pmid": "" }, { "name": "signaling receptor activity", "id": "GO:0038023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038023", "evidence": [ { "database": "UniProtKB", "id": "F1LVK3", "url": "https://www.uniprot.org/uniprotkb/F1LVK3" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of chondrocyte differentiation", "id": "GO:0032331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032331", "evidence": [ { "database": "UniProtKB", "id": "F1LVK3", "url": "https://www.uniprot.org/uniprotkb/F1LVK3" } ], "pmid": "" }, { "name": "negative regulation of collagen fibril organization", "id": "GO:1904027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904027", "evidence": [ { "database": "UniProtKB", "id": "F1LVK3", "url": "https://www.uniprot.org/uniprotkb/F1LVK3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1LVK3-1" }, { "uniprot_canonical_ac": "F1LVS9-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1LVS9", "url": "https://www.uniprot.org/uniprotkb/F1LVS9" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 579, "chemical_mass": 66129.0, "gene_names": "Zfp496;Zfp496;Zkscan17;Znf496", "protein_name": "Zinc finger protein 496", "disease": [], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "F1LVS9", "url": "https://www.uniprot.org/uniprotkb/F1LVS9" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1LVS9", "url": "https://www.uniprot.org/uniprotkb/F1LVS9" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "F1LVS9", "url": "https://www.uniprot.org/uniprotkb/F1LVS9" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "F1LVS9", "url": "https://www.uniprot.org/uniprotkb/F1LVS9" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "F1LVS9", "url": "https://www.uniprot.org/uniprotkb/F1LVS9" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1LVS9", "url": "https://www.uniprot.org/uniprotkb/F1LVS9" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "F1LVS9", "url": "https://www.uniprot.org/uniprotkb/F1LVS9" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "F1LVS9", "url": "https://www.uniprot.org/uniprotkb/F1LVS9" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "F1LVS9", "url": "https://www.uniprot.org/uniprotkb/F1LVS9" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1LVS9", "url": "https://www.uniprot.org/uniprotkb/F1LVS9" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "F1LVS9", "url": "https://www.uniprot.org/uniprotkb/F1LVS9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1LVS9-1" }, { "uniprot_canonical_ac": "F1LVV4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1LVV4", "url": "https://www.uniprot.org/uniprotkb/F1LVV4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 520, "chemical_mass": 56027.0, "gene_names": "Rcc2;RGD1309986;Rcc2", "protein_name": "Protein RCC2", "disease": [], "biological_process": [ { "name": "regulation of ruffle assembly", "id": "GO:1900027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900027", "evidence": [ { "database": "UniProtKB", "id": "F1LVV4", "url": "https://www.uniprot.org/uniprotkb/F1LVV4" } ], "pmid": "" }, { "name": "regulation of fibroblast migration", "id": "GO:0010762", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010762", "evidence": [ { "database": "UniProtKB", "id": "F1LVV4", "url": "https://www.uniprot.org/uniprotkb/F1LVV4" } ], "pmid": "" }, { "name": "integrin-mediated signaling pathway", "id": "GO:0007229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007229", "evidence": [ { "database": "UniProtKB", "id": "F1LVV4", "url": "https://www.uniprot.org/uniprotkb/F1LVV4" } ], "pmid": "" }, { "name": "positive regulation of G2/M transition of mitotic cell cycle", "id": "GO:0010971", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010971", "evidence": [ { "database": "UniProtKB", "id": "F1LVV4", "url": "https://www.uniprot.org/uniprotkb/F1LVV4" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "F1LVV4", "url": "https://www.uniprot.org/uniprotkb/F1LVV4" } ], "pmid": "" }, { "name": "establishment of protein localization", "id": "GO:0045184", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045184", "evidence": [ { "database": "UniProtKB", "id": "F1LVV4", "url": "https://www.uniprot.org/uniprotkb/F1LVV4" } ], "pmid": "" }, { "name": "regulation of cell migration", "id": "GO:0030334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030334", "evidence": [ { "database": "UniProtKB", "id": "F1LVV4", "url": "https://www.uniprot.org/uniprotkb/F1LVV4" } ], "pmid": "" }, { "name": "focal adhesion assembly", "id": "GO:0048041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048041", "evidence": [ { "database": "UniProtKB", "id": "F1LVV4", "url": "https://www.uniprot.org/uniprotkb/F1LVV4" } ], "pmid": "" }, { "name": "negative regulation of focal adhesion assembly", "id": "GO:0051895", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051895", "evidence": [ { "database": "UniProtKB", "id": "F1LVV4", "url": "https://www.uniprot.org/uniprotkb/F1LVV4" } ], "pmid": "" }, { "name": "negative regulation of GTPase activity", "id": "GO:0034260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034260", "evidence": [ { "database": "UniProtKB", "id": "F1LVV4", "url": "https://www.uniprot.org/uniprotkb/F1LVV4" } ], "pmid": "" }, { "name": "activation of GTPase activity", "id": "GO:0090630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090630", "evidence": [ { "database": "UniProtKB", "id": "F1LVV4", "url": "https://www.uniprot.org/uniprotkb/F1LVV4" } ], "pmid": "" }, { "name": "negative regulation of substrate adhesion-dependent cell spreading", "id": "GO:1900025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900025", "evidence": [ { "database": "UniProtKB", "id": "F1LVV4", "url": "https://www.uniprot.org/uniprotkb/F1LVV4" } ], "pmid": "" }, { "name": "chromosome passenger complex localization to kinetochore", "id": "GO:0072356", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072356", "evidence": [ { "database": "UniProtKB", "id": "F1LVV4", "url": "https://www.uniprot.org/uniprotkb/F1LVV4" } ], "pmid": "" }, { "name": "positive regulation of attachment of spindle microtubules to kinetochore", "id": "GO:0051987", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051987", "evidence": [ { "database": "UniProtKB", "id": "F1LVV4", "url": "https://www.uniprot.org/uniprotkb/F1LVV4" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1LVV4", "url": "https://www.uniprot.org/uniprotkb/F1LVV4" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "F1LVV4", "url": "https://www.uniprot.org/uniprotkb/F1LVV4" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1LVV4", "url": "https://www.uniprot.org/uniprotkb/F1LVV4" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1LVV4", "url": "https://www.uniprot.org/uniprotkb/F1LVV4" } ], "pmid": "" }, { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "F1LVV4", "url": "https://www.uniprot.org/uniprotkb/F1LVV4" } ], "pmid": "" }, { "name": "midbody", "id": "GO:0030496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030496", "evidence": [ { "database": "UniProtKB", "id": "F1LVV4", "url": "https://www.uniprot.org/uniprotkb/F1LVV4" } ], "pmid": "" }, { "name": "chromosome, centromeric core domain", "id": "GO:0034506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034506", "evidence": [ { "database": "UniProtKB", "id": "F1LVV4", "url": "https://www.uniprot.org/uniprotkb/F1LVV4" } ], "pmid": "" }, { "name": "mitotic spindle midzone", "id": "GO:1990023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990023", "evidence": [ { "database": "UniProtKB", "id": "F1LVV4", "url": "https://www.uniprot.org/uniprotkb/F1LVV4" } ], "pmid": "" } ], "molecular_function": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "F1LVV4", "url": "https://www.uniprot.org/uniprotkb/F1LVV4" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "F1LVV4", "url": "https://www.uniprot.org/uniprotkb/F1LVV4" } ], "pmid": "" }, { "name": "protein domain specific binding", "id": "GO:0019904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019904", "evidence": [ { "database": "UniProtKB", "id": "F1LVV4", "url": "https://www.uniprot.org/uniprotkb/F1LVV4" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "F1LVV4", "url": "https://www.uniprot.org/uniprotkb/F1LVV4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1LVV4-1" }, { "uniprot_canonical_ac": "F1LW89-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1LW89", "url": "https://www.uniprot.org/uniprotkb/F1LW89" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1955, "chemical_mass": 217340.0, "gene_names": "Greb1;Greb1;RGD1564091", "protein_name": "", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1LW89", "url": "https://www.uniprot.org/uniprotkb/F1LW89" } ], "pmid": "" } ], "biological_process": [ { "name": "morphogenesis of an epithelium", "id": "GO:0002009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002009", "evidence": [ { "database": "UniProtKB", "id": "F1LW89", "url": "https://www.uniprot.org/uniprotkb/F1LW89" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "F1LW89-1", "start_pos": "358", "end_pos": "358", "site_lbl": "Thr358", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 358, "start_aa": "Thr", "end_pos": 358, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr358", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "F1LW89-1" }, { "uniprot_canonical_ac": "F1LWB7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1LWB7", "url": "https://www.uniprot.org/uniprotkb/F1LWB7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 166, "chemical_mass": 18132.0, "gene_names": "AABR07027339.1", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1LWB7-1" }, { "uniprot_canonical_ac": "F1LWD2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1LWD2", "url": "https://www.uniprot.org/uniprotkb/F1LWD2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1141, "chemical_mass": 130973.0, "gene_names": "Cfap92;Cfap92", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1LWD2-1" }, { "uniprot_canonical_ac": "F1LWE4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1LWE4", "url": "https://www.uniprot.org/uniprotkb/F1LWE4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 759, "chemical_mass": 85874.0, "gene_names": "Adam25;Adam25l;Adam25;LOC100910977", "protein_name": "", "disease": [], "molecular_function": [ { "name": "metalloendopeptidase activity", "id": "GO:0004222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004222", "evidence": [ { "database": "UniProtKB", "id": "F1LWE4", "url": "https://www.uniprot.org/uniprotkb/F1LWE4" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1LWE4", "url": "https://www.uniprot.org/uniprotkb/F1LWE4" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1LWE4", "url": "https://www.uniprot.org/uniprotkb/F1LWE4" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "F1LWE4", "url": "https://www.uniprot.org/uniprotkb/F1LWE4" } ], "pmid": "" }, { "name": "sperm head plasma membrane", "id": "GO:1990913", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990913", "evidence": [ { "database": "UniProtKB", "id": "F1LWE4", "url": "https://www.uniprot.org/uniprotkb/F1LWE4" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "F1LWE4", "url": "https://www.uniprot.org/uniprotkb/F1LWE4" } ], "pmid": "" }, { "name": "male gonad development", "id": "GO:0008584", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008584", "evidence": [ { "database": "UniProtKB", "id": "F1LWE4", "url": "https://www.uniprot.org/uniprotkb/F1LWE4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1LWE4-1" }, { "uniprot_canonical_ac": "F1LWI8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1LWI8", "url": "https://www.uniprot.org/uniprotkb/F1LWI8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 329, "chemical_mass": 36969.0, "gene_names": "Cfap251;Wdr66", "protein_name": "", "disease": [ { "disease_id": "DOID:0111915", "name": "spermatogenic failure 33", "description": "A spermatogenic failure characterized by multiple morphologic abnormalities of the flagella resulting in immotile spermatozoa and infertility that has_material_basis_in homozygous or compound heterozygous mutation in the WDR66 gene on chromosome 12q24.31.", "url": "https://disease-ontology.org/term/DOID:0111915", "evidence": [ { "id": "0111915", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111915" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "sperm end piece", "id": "GO:0097229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097229", "evidence": [ { "database": "UniProtKB", "id": "F1LWI8", "url": "https://www.uniprot.org/uniprotkb/F1LWI8" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "F1LWI8", "url": "https://www.uniprot.org/uniprotkb/F1LWI8" } ], "pmid": "" }, { "name": "sperm flagellum", "id": "GO:0036126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036126", "evidence": [ { "database": "UniProtKB", "id": "F1LWI8", "url": "https://www.uniprot.org/uniprotkb/F1LWI8" } ], "pmid": "" }, { "name": "sperm midpiece", "id": "GO:0097225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097225", "evidence": [ { "database": "UniProtKB", "id": "F1LWI8", "url": "https://www.uniprot.org/uniprotkb/F1LWI8" } ], "pmid": "" } ], "biological_process": [ { "name": "flagellated sperm motility", "id": "GO:0030317", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030317", "evidence": [ { "database": "UniProtKB", "id": "F1LWI8", "url": "https://www.uniprot.org/uniprotkb/F1LWI8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1LWI8-1" }, { "uniprot_canonical_ac": "F1LWJ6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1LWJ6", "url": "https://www.uniprot.org/uniprotkb/F1LWJ6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1333, "chemical_mass": 151676.0, "gene_names": "Myo3b;Myo3b;RGD1560313", "protein_name": "non-specific serine/threonine protein kinase", "disease": [], "biological_process": [ { "name": "regulation of actin filament length", "id": "GO:0030832", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030832", "evidence": [ { "database": "UniProtKB", "id": "F1LWJ6", "url": "https://www.uniprot.org/uniprotkb/F1LWJ6" } ], "pmid": "" }, { "name": "visual perception", "id": "GO:0007601", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007601", "evidence": [ { "database": "UniProtKB", "id": "F1LWJ6", "url": "https://www.uniprot.org/uniprotkb/F1LWJ6" } ], "pmid": "" }, { "name": "protein autophosphorylation", "id": "GO:0046777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046777", "evidence": [ { "database": "UniProtKB", "id": "F1LWJ6", "url": "https://www.uniprot.org/uniprotkb/F1LWJ6" } ], "pmid": "" }, { "name": "sensory perception of sound", "id": "GO:0007605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007605", "evidence": [ { "database": "UniProtKB", "id": "F1LWJ6", "url": "https://www.uniprot.org/uniprotkb/F1LWJ6" } ], "pmid": "" }, { "name": "peptidyl-threonine phosphorylation", "id": "GO:0018107", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018107", "evidence": [ { "database": "UniProtKB", "id": "F1LWJ6", "url": "https://www.uniprot.org/uniprotkb/F1LWJ6" } ], "pmid": "" }, { "name": "peptidyl-serine phosphorylation", "id": "GO:0018105", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018105", "evidence": [ { "database": "UniProtKB", "id": "F1LWJ6", "url": "https://www.uniprot.org/uniprotkb/F1LWJ6" } ], "pmid": "" }, { "name": "positive regulation of filopodium assembly", "id": "GO:0051491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051491", "evidence": [ { "database": "UniProtKB", "id": "F1LWJ6", "url": "https://www.uniprot.org/uniprotkb/F1LWJ6" } ], "pmid": "" }, { "name": "auditory receptor cell stereocilium organization", "id": "GO:0060088", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060088", "evidence": [ { "database": "UniProtKB", "id": "F1LWJ6", "url": "https://www.uniprot.org/uniprotkb/F1LWJ6" } ], "pmid": "" }, { "name": "cochlea morphogenesis", "id": "GO:0090103", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090103", "evidence": [ { "database": "UniProtKB", "id": "F1LWJ6", "url": "https://www.uniprot.org/uniprotkb/F1LWJ6" } ], "pmid": "" } ], "molecular_function": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "F1LWJ6", "url": "https://www.uniprot.org/uniprotkb/F1LWJ6" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "F1LWJ6", "url": "https://www.uniprot.org/uniprotkb/F1LWJ6" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1LWJ6", "url": "https://www.uniprot.org/uniprotkb/F1LWJ6" } ], "pmid": "" }, { "name": "microfilament motor activity", "id": "GO:0000146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000146", "evidence": [ { "database": "UniProtKB", "id": "F1LWJ6", "url": "https://www.uniprot.org/uniprotkb/F1LWJ6" } ], "pmid": "" }, { "name": "cytoskeletal motor activity", "id": "GO:0003774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003774", "evidence": [ { "database": "UniProtKB", "id": "F1LWJ6", "url": "https://www.uniprot.org/uniprotkb/F1LWJ6" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1LWJ6", "url": "https://www.uniprot.org/uniprotkb/F1LWJ6" } ], "pmid": "" }, { "name": "photoreceptor inner segment", "id": "GO:0001917", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001917", "evidence": [ { "database": "UniProtKB", "id": "F1LWJ6", "url": "https://www.uniprot.org/uniprotkb/F1LWJ6" } ], "pmid": "" }, { "name": "filopodium tip", "id": "GO:0032433", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032433", "evidence": [ { "database": "UniProtKB", "id": "F1LWJ6", "url": "https://www.uniprot.org/uniprotkb/F1LWJ6" } ], "pmid": "" }, { "name": "photoreceptor outer segment", "id": "GO:0001750", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001750", "evidence": [ { "database": "UniProtKB", "id": "F1LWJ6", "url": "https://www.uniprot.org/uniprotkb/F1LWJ6" } ], "pmid": "" }, { "name": "stereocilium tip", "id": "GO:0032426", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032426", "evidence": [ { "database": "UniProtKB", "id": "F1LWJ6", "url": "https://www.uniprot.org/uniprotkb/F1LWJ6" } ], "pmid": "" }, { "name": "myosin complex", "id": "GO:0016459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016459", "evidence": [ { "database": "UniProtKB", "id": "F1LWJ6", "url": "https://www.uniprot.org/uniprotkb/F1LWJ6" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "F1LWJ6", "url": "https://www.uniprot.org/uniprotkb/F1LWJ6" } ], "pmid": "" }, { "name": "cell projection", "id": "GO:0042995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042995", "evidence": [ { "database": "UniProtKB", "id": "F1LWJ6", "url": "https://www.uniprot.org/uniprotkb/F1LWJ6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1LWJ6-1" }, { "uniprot_canonical_ac": "F1LWN1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1LWN1", "url": "https://www.uniprot.org/uniprotkb/F1LWN1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 968, "chemical_mass": 108973.0, "gene_names": "Ncoa7", "protein_name": "", "disease": [ { "disease_id": "DOID:0070339", "name": "cerebellar hyplasia/atrophy, epilepsy, and global developmental delay", "description": "A syndrome with a cerebellar malformation as a major feature characterized by cerebellar hypoplasia, bilateral retinal pigmentary changes, intellectual disability that can range from mild to moderate and pronounced language development delay. It presents with early developmental delay, central and peripheral non-progressive visual impairment or asymptomatic retinal changes, hypotonia, non-progressive ataxia and nystagmus.", "url": "https://disease-ontology.org/term/DOID:0070339", "evidence": [ { "id": "0070339", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070339" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "F1LWN1", "url": "https://www.uniprot.org/uniprotkb/F1LWN1" } ], "pmid": "" }, { "name": "nuclear receptor binding", "id": "GO:0016922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016922", "evidence": [ { "database": "UniProtKB", "id": "F1LWN1", "url": "https://www.uniprot.org/uniprotkb/F1LWN1" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1LWN1", "url": "https://www.uniprot.org/uniprotkb/F1LWN1" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "F1LWN1", "url": "https://www.uniprot.org/uniprotkb/F1LWN1" } ], "pmid": "" }, { "name": "response to oxidative stress", "id": "GO:0006979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006979", "evidence": [ { "database": "UniProtKB", "id": "F1LWN1", "url": "https://www.uniprot.org/uniprotkb/F1LWN1" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "F1LWN1", "url": "https://www.uniprot.org/uniprotkb/F1LWN1" } ], "pmid": "" }, { "name": "negative regulation of cellular response to oxidative stress", "id": "GO:1900408", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900408", "evidence": [ { "database": "UniProtKB", "id": "F1LWN1", "url": "https://www.uniprot.org/uniprotkb/F1LWN1" } ], "pmid": "" }, { "name": "negative regulation of peptidyl-cysteine S-nitrosylation", "id": "GO:1902083", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902083", "evidence": [ { "database": "UniProtKB", "id": "F1LWN1", "url": "https://www.uniprot.org/uniprotkb/F1LWN1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "F1LWN1-1", "start_pos": "588", "end_pos": "588", "site_lbl": "Thr588", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 588, "start_aa": "Thr", "end_pos": 588, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr588", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "F1LWN1-1" }, { "uniprot_canonical_ac": "F1LWV6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1LWV6", "url": "https://www.uniprot.org/uniprotkb/F1LWV6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1329, "chemical_mass": 149151.0, "gene_names": "Spata31f1;Fam205a", "protein_name": "", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1LWV6", "url": "https://www.uniprot.org/uniprotkb/F1LWV6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "F1LWV6-1", "start_pos": "788", "end_pos": "788", "site_lbl": "Thr788", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 788, "start_aa": "Thr", "end_pos": 788, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr788", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "F1LWV6-1" }, { "uniprot_canonical_ac": "F1LWZ3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1LWZ3", "url": "https://www.uniprot.org/uniprotkb/F1LWZ3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 825, "chemical_mass": 93257.0, "gene_names": "Rhbdf2;Rhbdf2;Rhbdl6", "protein_name": "Inactive rhomboid protein", "disease": [ { "disease_id": "DOID:0111506", "name": "palmoplantar keratoderma-esophageal carcinoma syndrome", "description": "A syndrome characterized by palmoplantar keratoderma and esophageal cancer that has_material_basis_in heterozygous mutation in the RHBDF2 gene on chromosome 17q25.1.", "url": "https://disease-ontology.org/term/DOID:0111506", "evidence": [ { "id": "0111506", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111506" } ], "weight": 0.0 } ], "biological_process": [ { "name": "negative regulation of protein secretion", "id": "GO:0050709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050709", "evidence": [ { "database": "UniProtKB", "id": "F1LWZ3", "url": "https://www.uniprot.org/uniprotkb/F1LWZ3" } ], "pmid": "" }, { "name": "protein localization to plasma membrane", "id": "GO:0072659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072659", "evidence": [ { "database": "UniProtKB", "id": "F1LWZ3", "url": "https://www.uniprot.org/uniprotkb/F1LWZ3" } ], "pmid": "" }, { "name": "regulation of protein secretion", "id": "GO:0050708", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050708", "evidence": [ { "database": "UniProtKB", "id": "F1LWZ3", "url": "https://www.uniprot.org/uniprotkb/F1LWZ3" } ], "pmid": "" }, { "name": "regulation of epidermal growth factor receptor signaling pathway", "id": "GO:0042058", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042058", "evidence": [ { "database": "UniProtKB", "id": "F1LWZ3", "url": "https://www.uniprot.org/uniprotkb/F1LWZ3" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1LWZ3", "url": "https://www.uniprot.org/uniprotkb/F1LWZ3" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "F1LWZ3", "url": "https://www.uniprot.org/uniprotkb/F1LWZ3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1LWZ3-1" }, { "uniprot_canonical_ac": "F1LWZ7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1LWZ7", "url": "https://www.uniprot.org/uniprotkb/F1LWZ7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1150, "chemical_mass": 131619.0, "gene_names": "Tbc1d8;IHoP;Tbc1d8", "protein_name": "TBC1 domain family member 8", "disease": [ { "disease_id": "DOID:0070357", "name": "nephrotic syndrome type 20", "description": "A familial nephrotic syndrome that has_material_basis_in X-linked renal disorder characterized by onset of steroid-resistant nephrotic syndrome and proteinuria in the first years of life in affected males.", "url": "https://disease-ontology.org/term/DOID:0070357", "evidence": [ { "id": "0070357", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070357" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "F1LWZ7", "url": "https://www.uniprot.org/uniprotkb/F1LWZ7" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "F1LWZ7", "url": "https://www.uniprot.org/uniprotkb/F1LWZ7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1LWZ7-1" }, { "uniprot_canonical_ac": "F1LXD8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1LXD8", "url": "https://www.uniprot.org/uniprotkb/F1LXD8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1075, "chemical_mass": 117094.0, "gene_names": "Emilin2;Emilin2", "protein_name": "EMILIN-2", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "F1LXD8", "url": "https://www.uniprot.org/uniprotkb/F1LXD8" } ], "pmid": "" } ], "biological_process": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "F1LXD8", "url": "https://www.uniprot.org/uniprotkb/F1LXD8" } ], "pmid": "" }, { "name": "positive regulation of apoptotic process", "id": "GO:0043065", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043065", "evidence": [ { "database": "UniProtKB", "id": "F1LXD8", "url": "https://www.uniprot.org/uniprotkb/F1LXD8" } ], "pmid": "" }, { "name": "negative regulation of cell migration", "id": "GO:0030336", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030336", "evidence": [ { "database": "UniProtKB", "id": "F1LXD8", "url": "https://www.uniprot.org/uniprotkb/F1LXD8" } ], "pmid": "" }, { "name": "positive regulation of angiogenesis", "id": "GO:0045766", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045766", "evidence": [ { "database": "UniProtKB", "id": "F1LXD8", "url": "https://www.uniprot.org/uniprotkb/F1LXD8" } ], "pmid": "" }, { "name": "positive regulation of blood coagulation", "id": "GO:0030194", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030194", "evidence": [ { "database": "UniProtKB", "id": "F1LXD8", "url": "https://www.uniprot.org/uniprotkb/F1LXD8" } ], "pmid": "" }, { "name": "positive regulation of defense response to bacterium", "id": "GO:1900426", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900426", "evidence": [ { "database": "UniProtKB", "id": "F1LXD8", "url": "https://www.uniprot.org/uniprotkb/F1LXD8" } ], "pmid": "" }, { "name": "positive regulation of platelet aggregation", "id": "GO:1901731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901731", "evidence": [ { "database": "UniProtKB", "id": "F1LXD8", "url": "https://www.uniprot.org/uniprotkb/F1LXD8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "F1LXD8-1", "start_pos": "239", "end_pos": "239", "site_lbl": "Thr239", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 239, "start_aa": "Thr", "end_pos": 239, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr239", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "F1LXD8-1", "start_pos": "814", "end_pos": "814", "site_lbl": "Thr814", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 814, "start_aa": "Thr", "end_pos": 814, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr814", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "F1LXD8-1", "start_pos": "919", "end_pos": "919", "site_lbl": "Thr919", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 919, "start_aa": "Thr", "end_pos": 919, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr919", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "F1LXD8-1" }, { "uniprot_canonical_ac": "F1LXF1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1LXF1", "url": "https://www.uniprot.org/uniprotkb/F1LXF1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1270, "chemical_mass": 143034.0, "gene_names": "Bcr;Bcr", "protein_name": "Breakpoint cluster region protein", "disease": [ { "disease_id": "DOID:1240", "name": "leukemia", "description": "A cancer that affects the blood or bone marrow characterized by an abnormal proliferation of blood cells.", "url": "https://disease-ontology.org/term/DOID:1240", "evidence": [ { "id": "1240", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1240" } ], "weight": 0.0 }, { "disease_id": "DOID:8552", "name": "chronic myeloid leukemia", "description": "A myeloid leukemia that is characterized by over production of white blood cells.", "url": "https://disease-ontology.org/term/DOID:8552", "evidence": [ { "id": "8552", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8552" } ], "weight": 0.0 }, { "disease_id": "DOID:9952", "name": "acute lymphoblastic leukemia", "description": "A acute leukemia that is characterized by over production of lymphoblasts.", "url": "https://disease-ontology.org/term/DOID:9952", "evidence": [ { "id": "9952", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9952" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "F1LXF1", "url": "https://www.uniprot.org/uniprotkb/F1LXF1" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1LXF1", "url": "https://www.uniprot.org/uniprotkb/F1LXF1" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1LXF1", "url": "https://www.uniprot.org/uniprotkb/F1LXF1" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "F1LXF1", "url": "https://www.uniprot.org/uniprotkb/F1LXF1" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1LXF1", "url": "https://www.uniprot.org/uniprotkb/F1LXF1" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "F1LXF1", "url": "https://www.uniprot.org/uniprotkb/F1LXF1" } ], "pmid": "" }, { "name": "dendritic spine", "id": "GO:0043197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043197", "evidence": [ { "database": "UniProtKB", "id": "F1LXF1", "url": "https://www.uniprot.org/uniprotkb/F1LXF1" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "F1LXF1", "url": "https://www.uniprot.org/uniprotkb/F1LXF1" } ], "pmid": "" }, { "name": "postsynaptic density, intracellular component", "id": "GO:0099092", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099092", "evidence": [ { "database": "UniProtKB", "id": "F1LXF1", "url": "https://www.uniprot.org/uniprotkb/F1LXF1" } ], "pmid": "" }, { "name": "Schaffer collateral - CA1 synapse", "id": "GO:0098685", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098685", "evidence": [ { "database": "UniProtKB", "id": "F1LXF1", "url": "https://www.uniprot.org/uniprotkb/F1LXF1" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "F1LXF1", "url": "https://www.uniprot.org/uniprotkb/F1LXF1" } ], "pmid": "" }, { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "F1LXF1", "url": "https://www.uniprot.org/uniprotkb/F1LXF1" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1LXF1", "url": "https://www.uniprot.org/uniprotkb/F1LXF1" } ], "pmid": "" }, { "name": "enzyme binding", "id": "GO:0019899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019899", "evidence": [ { "database": "UniProtKB", "id": "F1LXF1", "url": "https://www.uniprot.org/uniprotkb/F1LXF1" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "F1LXF1", "url": "https://www.uniprot.org/uniprotkb/F1LXF1" } ], "pmid": "" }, { "name": "protein serine kinase activity", "id": "GO:0106310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106310", "evidence": [ { "database": "UniProtKB", "id": "F1LXF1", "url": "https://www.uniprot.org/uniprotkb/F1LXF1" } ], "pmid": "" } ], "biological_process": [ { "name": "response to lipopolysaccharide", "id": "GO:0032496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032496", "evidence": [ { "database": "UniProtKB", "id": "F1LXF1", "url": "https://www.uniprot.org/uniprotkb/F1LXF1" } ], "pmid": "" }, { "name": "inner ear morphogenesis", "id": "GO:0042472", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042472", "evidence": [ { "database": "UniProtKB", "id": "F1LXF1", "url": "https://www.uniprot.org/uniprotkb/F1LXF1" } ], "pmid": "" }, { "name": "neuromuscular process controlling balance", "id": "GO:0050885", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050885", "evidence": [ { "database": "UniProtKB", "id": "F1LXF1", "url": "https://www.uniprot.org/uniprotkb/F1LXF1" } ], "pmid": "" }, { "name": "negative regulation of cell migration", "id": "GO:0030336", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030336", "evidence": [ { "database": "UniProtKB", "id": "F1LXF1", "url": "https://www.uniprot.org/uniprotkb/F1LXF1" } ], "pmid": "" }, { "name": "negative regulation of inflammatory response", "id": "GO:0050728", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050728", "evidence": [ { "database": "UniProtKB", "id": "F1LXF1", "url": "https://www.uniprot.org/uniprotkb/F1LXF1" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "F1LXF1", "url": "https://www.uniprot.org/uniprotkb/F1LXF1" } ], "pmid": "" }, { "name": "keratinocyte differentiation", "id": "GO:0030216", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030216", "evidence": [ { "database": "UniProtKB", "id": "F1LXF1", "url": "https://www.uniprot.org/uniprotkb/F1LXF1" } ], "pmid": "" }, { "name": "cellular response to lipopolysaccharide", "id": "GO:0071222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071222", "evidence": [ { "database": "UniProtKB", "id": "F1LXF1", "url": "https://www.uniprot.org/uniprotkb/F1LXF1" } ], "pmid": "" }, { "name": "brain development", "id": "GO:0007420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420", "evidence": [ { "database": "UniProtKB", "id": "F1LXF1", "url": "https://www.uniprot.org/uniprotkb/F1LXF1" } ], "pmid": "" }, { "name": "protein autophosphorylation", "id": "GO:0046777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046777", "evidence": [ { "database": "UniProtKB", "id": "F1LXF1", "url": "https://www.uniprot.org/uniprotkb/F1LXF1" } ], "pmid": "" }, { "name": "negative regulation of reactive oxygen species metabolic process", "id": "GO:2000378", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000378", "evidence": [ { "database": "UniProtKB", "id": "F1LXF1", "url": "https://www.uniprot.org/uniprotkb/F1LXF1" } ], "pmid": "" }, { "name": "negative regulation of cellular extravasation", "id": "GO:0002692", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002692", "evidence": [ { "database": "UniProtKB", "id": "F1LXF1", "url": "https://www.uniprot.org/uniprotkb/F1LXF1" } ], "pmid": "" }, { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "F1LXF1", "url": "https://www.uniprot.org/uniprotkb/F1LXF1" } ], "pmid": "" }, { "name": "regulation of Rho protein signal transduction", "id": "GO:0035023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035023", "evidence": [ { "database": "UniProtKB", "id": "F1LXF1", "url": "https://www.uniprot.org/uniprotkb/F1LXF1" } ], "pmid": "" }, { "name": "regulation of vascular permeability", "id": "GO:0043114", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043114", "evidence": [ { "database": "UniProtKB", "id": "F1LXF1", "url": "https://www.uniprot.org/uniprotkb/F1LXF1" } ], "pmid": "" }, { "name": "negative regulation of neutrophil degranulation", "id": "GO:0043314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043314", "evidence": [ { "database": "UniProtKB", "id": "F1LXF1", "url": "https://www.uniprot.org/uniprotkb/F1LXF1" } ], "pmid": "" }, { "name": "positive regulation of phagocytosis", "id": "GO:0050766", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050766", "evidence": [ { "database": "UniProtKB", "id": "F1LXF1", "url": "https://www.uniprot.org/uniprotkb/F1LXF1" } ], "pmid": "" }, { "name": "negative regulation of blood vessel remodeling", "id": "GO:0060313", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060313", "evidence": [ { "database": "UniProtKB", "id": "F1LXF1", "url": "https://www.uniprot.org/uniprotkb/F1LXF1" } ], "pmid": "" }, { "name": "focal adhesion assembly", "id": "GO:0048041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048041", "evidence": [ { "database": "UniProtKB", "id": "F1LXF1", "url": "https://www.uniprot.org/uniprotkb/F1LXF1" } ], "pmid": "" }, { "name": "modulation of chemical synaptic transmission", "id": "GO:0050804", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050804", "evidence": [ { "database": "UniProtKB", "id": "F1LXF1", "url": "https://www.uniprot.org/uniprotkb/F1LXF1" } ], "pmid": "" }, { "name": "activation of GTPase activity", "id": "GO:0090630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090630", "evidence": [ { "database": "UniProtKB", "id": "F1LXF1", "url": "https://www.uniprot.org/uniprotkb/F1LXF1" } ], "pmid": "" }, { "name": "intracellular protein transmembrane transport", "id": "GO:0065002", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0065002", "evidence": [ { "database": "UniProtKB", "id": "F1LXF1", "url": "https://www.uniprot.org/uniprotkb/F1LXF1" } ], "pmid": "" }, { "name": "renal system process", "id": "GO:0003014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003014", "evidence": [ { "database": "UniProtKB", "id": "F1LXF1", "url": "https://www.uniprot.org/uniprotkb/F1LXF1" } ], "pmid": "" }, { "name": "platelet-derived growth factor receptor signaling pathway", "id": "GO:0048008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048008", "evidence": [ { "database": "UniProtKB", "id": "F1LXF1", "url": "https://www.uniprot.org/uniprotkb/F1LXF1" } ], "pmid": "" }, { "name": "definitive hemopoiesis", "id": "GO:0060216", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060216", "evidence": [ { "database": "UniProtKB", "id": "F1LXF1", "url": "https://www.uniprot.org/uniprotkb/F1LXF1" } ], "pmid": "" }, { "name": "negative regulation of respiratory burst", "id": "GO:0060268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060268", "evidence": [ { "database": "UniProtKB", "id": "F1LXF1", "url": "https://www.uniprot.org/uniprotkb/F1LXF1" } ], "pmid": "" }, { "name": "homeostasis of number of cells", "id": "GO:0048872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048872", "evidence": [ { "database": "UniProtKB", "id": "F1LXF1", "url": "https://www.uniprot.org/uniprotkb/F1LXF1" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "F1LXF1", "url": "https://www.uniprot.org/uniprotkb/F1LXF1" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "F1LXF1", "url": "https://www.uniprot.org/uniprotkb/F1LXF1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "F1LXF1-1", "start_pos": "1263", "end_pos": "1263", "site_lbl": "Ser1263", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "F1LXF1", "url": "https://www.uniprot.org/uniprotkb/F1LXF1" } ] } ] }, { "uniprot_canonical_ac": "F1LXF1-1", "start_pos": "216", "end_pos": "216", "site_lbl": "Ser216", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "F1LXF1", "url": "https://www.uniprot.org/uniprotkb/F1LXF1" } ] } ] }, { "uniprot_canonical_ac": "F1LXF1-1", "start_pos": "237", "end_pos": "237", "site_lbl": "Ser237", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "F1LXF1", "url": "https://www.uniprot.org/uniprotkb/F1LXF1" } ] } ] }, { "uniprot_canonical_ac": "F1LXF1-1", "start_pos": "247", "end_pos": "247", "site_lbl": "Tyr247", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "F1LXF1", "url": "https://www.uniprot.org/uniprotkb/F1LXF1" } ] } ] }, { "uniprot_canonical_ac": "F1LXF1-1", "start_pos": "358", "end_pos": "358", "site_lbl": "Ser358", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "F1LXF1", "url": "https://www.uniprot.org/uniprotkb/F1LXF1" } ] } ] }, { "uniprot_canonical_ac": "F1LXF1-1", "start_pos": "379", "end_pos": "379", "site_lbl": "Ser379", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "F1LXF1", "url": "https://www.uniprot.org/uniprotkb/F1LXF1" } ] } ] }, { "uniprot_canonical_ac": "F1LXF1-1", "start_pos": "384", "end_pos": "384", "site_lbl": "Ser384", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "F1LXF1", "url": "https://www.uniprot.org/uniprotkb/F1LXF1" } ] } ] }, { "uniprot_canonical_ac": "F1LXF1-1", "start_pos": "387", "end_pos": "387", "site_lbl": "Thr387", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "F1LXF1", "url": "https://www.uniprot.org/uniprotkb/F1LXF1" } ] } ] }, { "uniprot_canonical_ac": "F1LXF1-1", "start_pos": "461", "end_pos": "461", "site_lbl": "Ser461", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "F1LXF1", "url": "https://www.uniprot.org/uniprotkb/F1LXF1" } ] } ] }, { "uniprot_canonical_ac": "F1LXF1-1", "start_pos": "465", "end_pos": "465", "site_lbl": "Ser465", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "F1LXF1", "url": "https://www.uniprot.org/uniprotkb/F1LXF1" } ] } ] }, { "uniprot_canonical_ac": "F1LXF1-1", "start_pos": "475", "end_pos": "475", "site_lbl": "Ser475", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "F1LXF1", "url": "https://www.uniprot.org/uniprotkb/F1LXF1" } ] } ] }, { "uniprot_canonical_ac": "F1LXF1-1", "start_pos": "487", "end_pos": "487", "site_lbl": "Ser487", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "F1LXF1", "url": "https://www.uniprot.org/uniprotkb/F1LXF1" } ] } ] }, { "uniprot_canonical_ac": "F1LXF1-1", "start_pos": "553", "end_pos": "553", "site_lbl": "Tyr553", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "F1LXF1", "url": "https://www.uniprot.org/uniprotkb/F1LXF1" } ] } ] }, { "uniprot_canonical_ac": "F1LXF1-1", "start_pos": "640", "end_pos": "640", "site_lbl": "Thr640", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "F1LXF1", "url": "https://www.uniprot.org/uniprotkb/F1LXF1" } ] } ] }, { "uniprot_canonical_ac": "F1LXF1-1", "start_pos": "643", "end_pos": "643", "site_lbl": "Tyr643", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "F1LXF1", "url": "https://www.uniprot.org/uniprotkb/F1LXF1" } ] } ] }, { "uniprot_canonical_ac": "F1LXF1-1", "start_pos": "692", "end_pos": "692", "site_lbl": "Thr692", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "F1LXF1", "url": "https://www.uniprot.org/uniprotkb/F1LXF1" } ] } ] } ], "record_id": "F1LXF1-1" }, { "uniprot_canonical_ac": "F1LXQ1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1LXQ1", "url": "https://www.uniprot.org/uniprotkb/F1LXQ1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 710, "chemical_mass": 79686.0, "gene_names": "Fbxo40;Fbxo40", "protein_name": "", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1LXQ1", "url": "https://www.uniprot.org/uniprotkb/F1LXQ1" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1LXQ1", "url": "https://www.uniprot.org/uniprotkb/F1LXQ1" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "F1LXQ1", "url": "https://www.uniprot.org/uniprotkb/F1LXQ1" } ], "pmid": "" } ], "biological_process": [ { "name": "muscle cell differentiation", "id": "GO:0042692", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042692", "evidence": [ { "database": "UniProtKB", "id": "F1LXQ1", "url": "https://www.uniprot.org/uniprotkb/F1LXQ1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1LXQ1-1" }, { "uniprot_canonical_ac": "F1M784-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1M784", "url": "https://www.uniprot.org/uniprotkb/F1M784" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 812, "chemical_mass": 91089.0, "gene_names": "Pik3ap1;LOC100361758;Pik3ap1", "protein_name": "Phosphoinositide 3-kinase adapter protein 1", "disease": [], "biological_process": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "F1M784", "url": "https://www.uniprot.org/uniprotkb/F1M784" } ], "pmid": "" }, { "name": "positive regulation of toll-like receptor signaling pathway", "id": "GO:0034123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034123", "evidence": [ { "database": "UniProtKB", "id": "F1M784", "url": "https://www.uniprot.org/uniprotkb/F1M784" } ], "pmid": "" }, { "name": "positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction", "id": "GO:0051897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051897", "evidence": [ { "database": "UniProtKB", "id": "F1M784", "url": "https://www.uniprot.org/uniprotkb/F1M784" } ], "pmid": "" }, { "name": "regulation of inflammatory response", "id": "GO:0050727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050727", "evidence": [ { "database": "UniProtKB", "id": "F1M784", "url": "https://www.uniprot.org/uniprotkb/F1M784" } ], "pmid": "" }, { "name": "negative regulation of toll-like receptor signaling pathway", "id": "GO:0034122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034122", "evidence": [ { "database": "UniProtKB", "id": "F1M784", "url": "https://www.uniprot.org/uniprotkb/F1M784" } ], "pmid": "" }, { "name": "toll-like receptor 2 signaling pathway", "id": "GO:0034134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034134", "evidence": [ { "database": "UniProtKB", "id": "F1M784", "url": "https://www.uniprot.org/uniprotkb/F1M784" } ], "pmid": "" }, { "name": "toll-like receptor 4 signaling pathway", "id": "GO:0034142", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034142", "evidence": [ { "database": "UniProtKB", "id": "F1M784", "url": "https://www.uniprot.org/uniprotkb/F1M784" } ], "pmid": "" }, { "name": "toll-like receptor 7 signaling pathway", "id": "GO:0034154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034154", "evidence": [ { "database": "UniProtKB", "id": "F1M784", "url": "https://www.uniprot.org/uniprotkb/F1M784" } ], "pmid": "" }, { "name": "toll-like receptor 9 signaling pathway", "id": "GO:0034162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034162", "evidence": [ { "database": "UniProtKB", "id": "F1M784", "url": "https://www.uniprot.org/uniprotkb/F1M784" } ], "pmid": "" } ], "molecular_function": [ { "name": "signaling receptor binding", "id": "GO:0005102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005102", "evidence": [ { "database": "UniProtKB", "id": "F1M784", "url": "https://www.uniprot.org/uniprotkb/F1M784" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "F1M784", "url": "https://www.uniprot.org/uniprotkb/F1M784" } ], "pmid": "" }, { "name": "phosphatidylinositol 3-kinase regulatory subunit binding", "id": "GO:0036312", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036312", "evidence": [ { "database": "UniProtKB", "id": "F1M784", "url": "https://www.uniprot.org/uniprotkb/F1M784" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1M784", "url": "https://www.uniprot.org/uniprotkb/F1M784" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1M784", "url": "https://www.uniprot.org/uniprotkb/F1M784" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1M784", "url": "https://www.uniprot.org/uniprotkb/F1M784" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1M784", "url": "https://www.uniprot.org/uniprotkb/F1M784" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "F1M784-1", "start_pos": "541", "end_pos": "541", "site_lbl": "Thr541", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 541, "start_aa": "Thr", "end_pos": 541, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr541", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "F1M784-1", "start_pos": "763", "end_pos": "763", "site_lbl": "Thr763", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 763, "start_aa": "Thr", "end_pos": 763, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr763", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "F1M784-1" }, { "uniprot_canonical_ac": "F1LXT8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1LXT8", "url": "https://www.uniprot.org/uniprotkb/F1LXT8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 4156, "chemical_mass": 476091.0, "gene_names": "Dnah6;Dnah6;Dnahc6;axo a", "protein_name": "", "disease": [], "biological_process": [ { "name": "cilium movement involved in cell motility", "id": "GO:0060294", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060294", "evidence": [ { "database": "UniProtKB", "id": "F1LXT8", "url": "https://www.uniprot.org/uniprotkb/F1LXT8" } ], "pmid": "" }, { "name": "microtubule-based movement", "id": "GO:0007018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007018", "evidence": [ { "database": "UniProtKB", "id": "F1LXT8", "url": "https://www.uniprot.org/uniprotkb/F1LXT8" } ], "pmid": "" } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1LXT8", "url": "https://www.uniprot.org/uniprotkb/F1LXT8" } ], "pmid": "" }, { "name": "minus-end-directed microtubule motor activity", "id": "GO:0008569", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008569", "evidence": [ { "database": "UniProtKB", "id": "F1LXT8", "url": "https://www.uniprot.org/uniprotkb/F1LXT8" } ], "pmid": "" }, { "name": "dynein light intermediate chain binding", "id": "GO:0051959", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051959", "evidence": [ { "database": "UniProtKB", "id": "F1LXT8", "url": "https://www.uniprot.org/uniprotkb/F1LXT8" } ], "pmid": "" }, { "name": "dynein intermediate chain binding", "id": "GO:0045505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045505", "evidence": [ { "database": "UniProtKB", "id": "F1LXT8", "url": "https://www.uniprot.org/uniprotkb/F1LXT8" } ], "pmid": "" } ], "cellular_component": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "F1LXT8", "url": "https://www.uniprot.org/uniprotkb/F1LXT8" } ], "pmid": "" }, { "name": "sperm flagellum", "id": "GO:0036126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036126", "evidence": [ { "database": "UniProtKB", "id": "F1LXT8", "url": "https://www.uniprot.org/uniprotkb/F1LXT8" } ], "pmid": "" }, { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "F1LXT8", "url": "https://www.uniprot.org/uniprotkb/F1LXT8" } ], "pmid": "" }, { "name": "dynein complex", "id": "GO:0030286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030286", "evidence": [ { "database": "UniProtKB", "id": "F1LXT8", "url": "https://www.uniprot.org/uniprotkb/F1LXT8" } ], "pmid": "" }, { "name": "9+2 motile cilium", "id": "GO:0097729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097729", "evidence": [ { "database": "UniProtKB", "id": "F1LXT8", "url": "https://www.uniprot.org/uniprotkb/F1LXT8" } ], "pmid": "" }, { "name": "motile cilium", "id": "GO:0031514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031514", "evidence": [ { "database": "UniProtKB", "id": "F1LXT8", "url": "https://www.uniprot.org/uniprotkb/F1LXT8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "F1LXT8-1", "start_pos": "1762", "end_pos": "1762", "site_lbl": "Thr1762", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" }, { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "reported site T1750 is on non-canonical isoform A0A8I6ADI4-1 which maps to canonical isoform site F1LXT8-1:1762", "icn3d_view": {}, "start_pos": 1762, "start_aa": "Thr", "end_pos": 1762, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1762", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "F1LXT8-1", "start_pos": "2230", "end_pos": "2230", "site_lbl": "Thr2230", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" }, { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "reported site T2218 is on non-canonical isoform A0ABK0LNJ3-1 which maps to canonical isoform site F1LXT8-1:2230", "icn3d_view": {}, "start_pos": 2230, "start_aa": "Thr", "end_pos": 2230, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2230", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "F1LXT8-1", "start_pos": "2294", "end_pos": "2294", "site_lbl": "Thr2294", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" }, { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "reported site T2282 is on non-canonical isoform A0ABK0LNJ3-1 which maps to canonical isoform site F1LXT8-1:2294", "icn3d_view": {}, "start_pos": 2294, "start_aa": "Thr", "end_pos": 2294, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2294", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "F1LXT8-1" }, { "uniprot_canonical_ac": "F1LYB3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1LYB3", "url": "https://www.uniprot.org/uniprotkb/F1LYB3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1108, "chemical_mass": 122536.0, "gene_names": "Tmem132c;RGD1305669;Tmem132c", "protein_name": "", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1LYB3", "url": "https://www.uniprot.org/uniprotkb/F1LYB3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1LYB3-1" }, { "uniprot_canonical_ac": "F1LYC7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1LYC7", "url": "https://www.uniprot.org/uniprotkb/F1LYC7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1788, "chemical_mass": 191180.0, "gene_names": "Bcorl1;Bcorl1;RGD1566108", "protein_name": "", "disease": [ { "disease_id": "DOID:0111841", "name": "Shukla-Vernon syndrome", "description": "A syndrome characterized by global developmental delay, variably impaired intellectual development, variable dysmorphic features, and behavioral abnormalities, including autism spectrum disorder and ADHD that has_material_basis_in hemizygous mutation in the BCORL1 gene on chromosome Xq26.1.", "url": "https://disease-ontology.org/term/DOID:0111841", "evidence": [ { "id": "0111841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111841" } ], "weight": 0.0 }, { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 } ], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "F1LYC7", "url": "https://www.uniprot.org/uniprotkb/F1LYC7" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1LYC7", "url": "https://www.uniprot.org/uniprotkb/F1LYC7" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "F1LYC7", "url": "https://www.uniprot.org/uniprotkb/F1LYC7" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1LYC7", "url": "https://www.uniprot.org/uniprotkb/F1LYC7" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1LYC7", "url": "https://www.uniprot.org/uniprotkb/F1LYC7" } ], "pmid": "" } ], "molecular_function": [ { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "F1LYC7", "url": "https://www.uniprot.org/uniprotkb/F1LYC7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "F1LYC7-1", "start_pos": "1268", "end_pos": "1268", "site_lbl": "Thr1268", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1268, "start_aa": "Thr", "end_pos": 1268, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1268", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "F1LYC7-1", "start_pos": "214", "end_pos": "214", "site_lbl": "Thr214", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 214, "start_aa": "Thr", "end_pos": 214, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr214", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "F1LYC7-1", "start_pos": "303", "end_pos": "303", "site_lbl": "Thr303", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 303, "start_aa": "Thr", "end_pos": 303, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr303", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "F1LYC7-1", "start_pos": "359", "end_pos": "359", "site_lbl": "Thr359", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 359, "start_aa": "Thr", "end_pos": 359, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr359", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "F1LYC7-1", "start_pos": "361", "end_pos": "361", "site_lbl": "Thr361", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 361, "start_aa": "Thr", "end_pos": 361, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr361", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "F1LYC7-1", "start_pos": "379", "end_pos": "379", "site_lbl": "Thr379", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 379, "start_aa": "Thr", "end_pos": 379, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr379", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "F1LYC7-1", "start_pos": "385", "end_pos": "385", "site_lbl": "Thr385", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 385, "start_aa": "Thr", "end_pos": 385, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr385", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "F1LYC7-1", "start_pos": "395", "end_pos": "395", "site_lbl": "Thr395", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 395, "start_aa": "Thr", "end_pos": 395, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr395", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "F1LYC7-1" }, { "uniprot_canonical_ac": "F1LYD6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1LYD6", "url": "https://www.uniprot.org/uniprotkb/F1LYD6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 342, "chemical_mass": 39346.0, "gene_names": "Cdkl4;Cdkl4", "protein_name": "cyclin-dependent kinase", "disease": [], "molecular_function": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "F1LYD6", "url": "https://www.uniprot.org/uniprotkb/F1LYD6" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1LYD6", "url": "https://www.uniprot.org/uniprotkb/F1LYD6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1LYD6-1" }, { "uniprot_canonical_ac": "F1LYH5-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1LYH5", "url": "https://www.uniprot.org/uniprotkb/F1LYH5" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 677, "chemical_mass": 75769.0, "gene_names": "Hdlbpl1;AABR07040251.1;Hdlbpl1;RGD1562485", "protein_name": "Vigilin", "disease": [ { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "F1LYH5", "url": "https://www.uniprot.org/uniprotkb/F1LYH5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1LYH5-1" }, { "uniprot_canonical_ac": "F1LYU9-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1LYU9", "url": "https://www.uniprot.org/uniprotkb/F1LYU9" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 285, "chemical_mass": 32180.0, "gene_names": "Cd209fl1;LOC100363064", "protein_name": "", "disease": [], "biological_process": [ { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "F1LYU9", "url": "https://www.uniprot.org/uniprotkb/F1LYU9" } ], "pmid": "" } ], "cellular_component": [ { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "F1LYU9", "url": "https://www.uniprot.org/uniprotkb/F1LYU9" } ], "pmid": "" } ], "molecular_function": [ { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "F1LYU9", "url": "https://www.uniprot.org/uniprotkb/F1LYU9" } ], "pmid": "" }, { "name": "pattern recognition receptor activity", "id": "GO:0038187", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038187", "evidence": [ { "database": "UniProtKB", "id": "F1LYU9", "url": "https://www.uniprot.org/uniprotkb/F1LYU9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1LYU9-1" }, { "uniprot_canonical_ac": "F1LYW9-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1LYW9", "url": "https://www.uniprot.org/uniprotkb/F1LYW9" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 449, "chemical_mass": 50275.0, "gene_names": "Fam169b", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1LYW9-1" }, { "uniprot_canonical_ac": "F1LYX9-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1LYX9", "url": "https://www.uniprot.org/uniprotkb/F1LYX9" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1128, "chemical_mass": 122290.0, "gene_names": "Dsg2;Dsg2", "protein_name": "", "disease": [ { "disease_id": "DOID:0050431", "name": "arrhythmogenic right ventricular cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by hypokinetic areas involving the free wall of the right ventricle, with fibrofatty replacement of the right ventricular myocardium, with associated arrhythmias originating in the right ventricle and limited or no involvement of the left ventricle.", "url": "https://disease-ontology.org/term/DOID:0050431", "evidence": [ { "id": "0050431", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050431" } ], "weight": 0.0 }, { "disease_id": "DOID:0060036", "name": "intrinsic cardiomyopathy", "description": "A cardiomyopathy that is characterized as weakness in the muscle of the heart that is not due to an identifiable external cause.", "url": "https://disease-ontology.org/term/DOID:0060036", "evidence": [ { "id": "0060036", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060036" } ], "weight": 0.0 }, { "disease_id": "DOID:0110081", "name": "arrhythmogenic right ventricular dysplasia 10", "description": "An arrhythmogenic right ventricular dysplasia that has_material_basis_in heterozygous mutation in the desmoglein-2 gene (DSG2) on chromosome 18q12.", "url": "https://disease-ontology.org/term/DOID:0110081", "evidence": [ { "id": "0110081", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110081" } ], "weight": 0.0 }, { "disease_id": "DOID:0110458", "name": "dilated cardiomyopathy 1BB", "description": "A dilated cardiomyopathy that has_material_basis_in mutation the DSG2 gene on chromosome 18q12.1.", "url": "https://disease-ontology.org/term/DOID:0110458", "evidence": [ { "id": "0110458", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110458" } ], "weight": 0.0 }, { "disease_id": "DOID:12930", "name": "dilated cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by an an enlarged heart and damage to the myocardium causing the heart to pump blood inefficiently.", "url": "https://disease-ontology.org/term/DOID:12930", "evidence": [ { "id": "12930", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12930" } ], "weight": 0.0 }, { "disease_id": "DOID:9538", "name": "multiple myeloma", "description": "A myeloid neoplasm that is located_in the plasma cells in bone marrow.", "url": "https://disease-ontology.org/term/DOID:9538", "evidence": [ { "id": "9538", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9538" } ], "weight": 0.0 } ], "biological_process": [ { "name": "positive regulation of sprouting angiogenesis", "id": "GO:1903672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903672", "evidence": [ { "database": "UniProtKB", "id": "F1LYX9", "url": "https://www.uniprot.org/uniprotkb/F1LYX9" } ], "pmid": "" }, { "name": "positive regulation of stem cell population maintenance", "id": "GO:1902459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902459", "evidence": [ { "database": "UniProtKB", "id": "F1LYX9", "url": "https://www.uniprot.org/uniprotkb/F1LYX9" } ], "pmid": "" }, { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "F1LYX9", "url": "https://www.uniprot.org/uniprotkb/F1LYX9" } ], "pmid": "" }, { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "F1LYX9", "url": "https://www.uniprot.org/uniprotkb/F1LYX9" } ], "pmid": "" }, { "name": "positive regulation of cell adhesion", "id": "GO:0045785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045785", "evidence": [ { "database": "UniProtKB", "id": "F1LYX9", "url": "https://www.uniprot.org/uniprotkb/F1LYX9" } ], "pmid": "" }, { "name": "regulation of heart rate by cardiac conduction", "id": "GO:0086091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0086091", "evidence": [ { "database": "UniProtKB", "id": "F1LYX9", "url": "https://www.uniprot.org/uniprotkb/F1LYX9" } ], "pmid": "" }, { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "F1LYX9", "url": "https://www.uniprot.org/uniprotkb/F1LYX9" } ], "pmid": "" }, { "name": "response to progesterone", "id": "GO:0032570", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032570", "evidence": [ { "database": "UniProtKB", "id": "F1LYX9", "url": "https://www.uniprot.org/uniprotkb/F1LYX9" } ], "pmid": "" }, { "name": "maternal process involved in female pregnancy", "id": "GO:0060135", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060135", "evidence": [ { "database": "UniProtKB", "id": "F1LYX9", "url": "https://www.uniprot.org/uniprotkb/F1LYX9" } ], "pmid": "" }, { "name": "negative regulation of endothelial cell differentiation", "id": "GO:0045602", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045602", "evidence": [ { "database": "UniProtKB", "id": "F1LYX9", "url": "https://www.uniprot.org/uniprotkb/F1LYX9" } ], "pmid": "" }, { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "F1LYX9", "url": "https://www.uniprot.org/uniprotkb/F1LYX9" } ], "pmid": "" }, { "name": "regulation of ventricular cardiac muscle cell action potential", "id": "GO:0098911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098911", "evidence": [ { "database": "UniProtKB", "id": "F1LYX9", "url": "https://www.uniprot.org/uniprotkb/F1LYX9" } ], "pmid": "" }, { "name": "stem cell proliferation", "id": "GO:0072089", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072089", "evidence": [ { "database": "UniProtKB", "id": "F1LYX9", "url": "https://www.uniprot.org/uniprotkb/F1LYX9" } ], "pmid": "" }, { "name": "bundle of His cell-Purkinje myocyte adhesion involved in cell communication", "id": "GO:0086073", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0086073", "evidence": [ { "database": "UniProtKB", "id": "F1LYX9", "url": "https://www.uniprot.org/uniprotkb/F1LYX9" } ], "pmid": "" }, { "name": "desmosome organization", "id": "GO:0002934", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002934", "evidence": [ { "database": "UniProtKB", "id": "F1LYX9", "url": "https://www.uniprot.org/uniprotkb/F1LYX9" } ], "pmid": "" }, { "name": "Purkinje myocyte development", "id": "GO:0003165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003165", "evidence": [ { "database": "UniProtKB", "id": "F1LYX9", "url": "https://www.uniprot.org/uniprotkb/F1LYX9" } ], "pmid": "" }, { "name": "mesenchymal to epithelial transition", "id": "GO:0060231", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060231", "evidence": [ { "database": "UniProtKB", "id": "F1LYX9", "url": "https://www.uniprot.org/uniprotkb/F1LYX9" } ], "pmid": "" }, { "name": "negative regulation of epithelial to mesenchymal transition", "id": "GO:0010719", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010719", "evidence": [ { "database": "UniProtKB", "id": "F1LYX9", "url": "https://www.uniprot.org/uniprotkb/F1LYX9" } ], "pmid": "" }, { "name": "negative regulation of inflammatory response to wounding", "id": "GO:0106015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106015", "evidence": [ { "database": "UniProtKB", "id": "F1LYX9", "url": "https://www.uniprot.org/uniprotkb/F1LYX9" } ], "pmid": "" }, { "name": "positive regulation of protein localization to cell-cell junction", "id": "GO:0150107", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0150107", "evidence": [ { "database": "UniProtKB", "id": "F1LYX9", "url": "https://www.uniprot.org/uniprotkb/F1LYX9" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1LYX9", "url": "https://www.uniprot.org/uniprotkb/F1LYX9" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1LYX9", "url": "https://www.uniprot.org/uniprotkb/F1LYX9" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "F1LYX9", "url": "https://www.uniprot.org/uniprotkb/F1LYX9" } ], "pmid": "" }, { "name": "cell junction", "id": "GO:0030054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030054", "evidence": [ { "database": "UniProtKB", "id": "F1LYX9", "url": "https://www.uniprot.org/uniprotkb/F1LYX9" } ], "pmid": "" }, { "name": "intercalated disc", "id": "GO:0014704", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014704", "evidence": [ { "database": "UniProtKB", "id": "F1LYX9", "url": "https://www.uniprot.org/uniprotkb/F1LYX9" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "F1LYX9", "url": "https://www.uniprot.org/uniprotkb/F1LYX9" } ], "pmid": "" }, { "name": "lateral plasma membrane", "id": "GO:0016328", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016328", "evidence": [ { "database": "UniProtKB", "id": "F1LYX9", "url": "https://www.uniprot.org/uniprotkb/F1LYX9" } ], "pmid": "" }, { "name": "desmosome", "id": "GO:0030057", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030057", "evidence": [ { "database": "UniProtKB", "id": "F1LYX9", "url": "https://www.uniprot.org/uniprotkb/F1LYX9" } ], "pmid": "" } ], "molecular_function": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "F1LYX9", "url": "https://www.uniprot.org/uniprotkb/F1LYX9" } ], "pmid": "" }, { "name": "cell adhesion molecule binding", "id": "GO:0050839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050839", "evidence": [ { "database": "UniProtKB", "id": "F1LYX9", "url": "https://www.uniprot.org/uniprotkb/F1LYX9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1LYX9-1" }, { "uniprot_canonical_ac": "F1M098-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1M098", "url": "https://www.uniprot.org/uniprotkb/F1M098" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 239, "chemical_mass": 26944.0, "gene_names": "Cimip3;Cimip3;Guca1anb;LOC100912849", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "F1M098-1", "start_pos": "150", "end_pos": "150", "site_lbl": "Thr150", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 150, "start_aa": "Thr", "end_pos": 150, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr150", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "F1M098-1", "start_pos": "152", "end_pos": "152", "site_lbl": "Thr152", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 152, "start_aa": "Thr", "end_pos": 152, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr152", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "F1M098-1" }, { "uniprot_canonical_ac": "F1M0Q9-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1M0Q9", "url": "https://www.uniprot.org/uniprotkb/F1M0Q9" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 503, "chemical_mass": 55700.0, "gene_names": "Pm20d1;Pm20d1;RGD1564063", "protein_name": "N-fatty-acyl-amino acid synthase/hydrolase PM20D1", "disease": [], "molecular_function": [ { "name": "aminoacylase activity", "id": "GO:0004046", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004046", "evidence": [ { "database": "UniProtKB", "id": "F1M0Q9", "url": "https://www.uniprot.org/uniprotkb/F1M0Q9" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1M0Q9", "url": "https://www.uniprot.org/uniprotkb/F1M0Q9" } ], "pmid": "" }, { "name": "peptidase activity", "id": "GO:0008233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008233", "evidence": [ { "database": "UniProtKB", "id": "F1M0Q9", "url": "https://www.uniprot.org/uniprotkb/F1M0Q9" } ], "pmid": "" }, { "name": "hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides", "id": "GO:0016811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016811", "evidence": [ { "database": "UniProtKB", "id": "F1M0Q9", "url": "https://www.uniprot.org/uniprotkb/F1M0Q9" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "F1M0Q9", "url": "https://www.uniprot.org/uniprotkb/F1M0Q9" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "F1M0Q9", "url": "https://www.uniprot.org/uniprotkb/F1M0Q9" } ], "pmid": "" }, { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "F1M0Q9", "url": "https://www.uniprot.org/uniprotkb/F1M0Q9" } ], "pmid": "" }, { "name": "energy homeostasis", "id": "GO:0097009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097009", "evidence": [ { "database": "UniProtKB", "id": "F1M0Q9", "url": "https://www.uniprot.org/uniprotkb/F1M0Q9" } ], "pmid": "" }, { "name": "amino acid metabolic process", "id": "GO:0006520", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006520", "evidence": [ { "database": "UniProtKB", "id": "F1M0Q9", "url": "https://www.uniprot.org/uniprotkb/F1M0Q9" } ], "pmid": "" }, { "name": "amide biosynthetic process", "id": "GO:0043604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043604", "evidence": [ { "database": "UniProtKB", "id": "F1M0Q9", "url": "https://www.uniprot.org/uniprotkb/F1M0Q9" } ], "pmid": "" }, { "name": "amide catabolic process", "id": "GO:0043605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043605", "evidence": [ { "database": "UniProtKB", "id": "F1M0Q9", "url": "https://www.uniprot.org/uniprotkb/F1M0Q9" } ], "pmid": "" }, { "name": "adaptive thermogenesis", "id": "GO:1990845", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990845", "evidence": [ { "database": "UniProtKB", "id": "F1M0Q9", "url": "https://www.uniprot.org/uniprotkb/F1M0Q9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1M0Q9-1" }, { "uniprot_canonical_ac": "F1M0R6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1M0R6", "url": "https://www.uniprot.org/uniprotkb/F1M0R6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 339, "chemical_mass": 37572.0, "gene_names": "Fancf;Fancf;RGD1561456", "protein_name": "Fanconi anemia group F protein", "disease": [ { "disease_id": "DOID:0050865", "name": "tongue squamous cell carcinoma", "description": "A head and neck squamous cell carcinoma that is located_in the tongue.", "url": "https://disease-ontology.org/term/DOID:0050865", "evidence": [ { "id": "0050865", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050865" } ], "weight": 0.0 }, { "disease_id": "DOID:0111088", "name": "Fanconi anemia complementation group F", "description": "A Fanconi anemia that has_material_basis_in homozygous or compound heterozygous mutation in the FANCF gene on chromosome 11p15.", "url": "https://disease-ontology.org/term/DOID:0111088", "evidence": [ { "id": "0111088", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111088" } ], "weight": 0.0 }, { "disease_id": "DOID:2999", "name": "granulosa cell tumor", "description": "A sex cord-gonadal stromal tumor that has_material_basis_in granulosa cells and arises from the sex cord stroma.", "url": "https://disease-ontology.org/term/DOID:2999", "evidence": [ { "id": "2999", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2999" } ], "weight": 0.0 }, { "disease_id": "DOID:4943", "name": "adenocarcinoma in situ", "description": "An in situ carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:4943", "evidence": [ { "id": "4943", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4943" } ], "weight": 0.0 }, { "disease_id": "DOID:5426", "name": "primary ovarian insufficiency", "description": "An ovarian disease where ovaries do not produce estrogen despite high levels of circulating gonadotropins in women under 40.", "url": "https://disease-ontology.org/term/DOID:5426", "evidence": [ { "id": "5426", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5426" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "Fanconi anaemia nuclear complex", "id": "GO:0043240", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043240", "evidence": [ { "database": "UniProtKB", "id": "F1M0R6", "url": "https://www.uniprot.org/uniprotkb/F1M0R6" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1M0R6", "url": "https://www.uniprot.org/uniprotkb/F1M0R6" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "F1M0R6", "url": "https://www.uniprot.org/uniprotkb/F1M0R6" } ], "pmid": "" } ], "biological_process": [ { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "F1M0R6", "url": "https://www.uniprot.org/uniprotkb/F1M0R6" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "F1M0R6", "url": "https://www.uniprot.org/uniprotkb/F1M0R6" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "F1M0R6", "url": "https://www.uniprot.org/uniprotkb/F1M0R6" } ], "pmid": "" }, { "name": "ovarian follicle development", "id": "GO:0001541", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001541", "evidence": [ { "database": "UniProtKB", "id": "F1M0R6", "url": "https://www.uniprot.org/uniprotkb/F1M0R6" } ], "pmid": "" }, { "name": "interstrand cross-link repair", "id": "GO:0036297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036297", "evidence": [ { "database": "UniProtKB", "id": "F1M0R6", "url": "https://www.uniprot.org/uniprotkb/F1M0R6" } ], "pmid": "" } ], "molecular_function": [ { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "F1M0R6", "url": "https://www.uniprot.org/uniprotkb/F1M0R6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1M0R6-1" }, { "uniprot_canonical_ac": "F1M107-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1M107", "url": "https://www.uniprot.org/uniprotkb/F1M107" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 403, "chemical_mass": 44490.0, "gene_names": "Stac;Stac", "protein_name": "SH3 and cysteine-rich domain-containing protein", "disease": [], "biological_process": [ { "name": "skeletal muscle contraction", "id": "GO:0003009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003009", "evidence": [ { "database": "UniProtKB", "id": "F1M107", "url": "https://www.uniprot.org/uniprotkb/F1M107" } ], "pmid": "" }, { "name": "muscle contraction", "id": "GO:0006936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006936", "evidence": [ { "database": "UniProtKB", "id": "F1M107", "url": "https://www.uniprot.org/uniprotkb/F1M107" } ], "pmid": "" }, { "name": "cellular response to heat", "id": "GO:0034605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034605", "evidence": [ { "database": "UniProtKB", "id": "F1M107", "url": "https://www.uniprot.org/uniprotkb/F1M107" } ], "pmid": "" }, { "name": "positive regulation of protein localization to plasma membrane", "id": "GO:1903078", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903078", "evidence": [ { "database": "UniProtKB", "id": "F1M107", "url": "https://www.uniprot.org/uniprotkb/F1M107" } ], "pmid": "" }, { "name": "positive regulation of cation channel activity", "id": "GO:2001259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001259", "evidence": [ { "database": "UniProtKB", "id": "F1M107", "url": "https://www.uniprot.org/uniprotkb/F1M107" } ], "pmid": "" }, { "name": "regulation of voltage-gated calcium channel activity", "id": "GO:1901385", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901385", "evidence": [ { "database": "UniProtKB", "id": "F1M107", "url": "https://www.uniprot.org/uniprotkb/F1M107" } ], "pmid": "" }, { "name": "positive regulation of voltage-gated calcium channel activity", "id": "GO:1901387", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901387", "evidence": [ { "database": "UniProtKB", "id": "F1M107", "url": "https://www.uniprot.org/uniprotkb/F1M107" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1M107", "url": "https://www.uniprot.org/uniprotkb/F1M107" } ], "pmid": "" }, { "name": "cytoplasmic side of plasma membrane", "id": "GO:0009898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009898", "evidence": [ { "database": "UniProtKB", "id": "F1M107", "url": "https://www.uniprot.org/uniprotkb/F1M107" } ], "pmid": "" }, { "name": "T-tubule", "id": "GO:0030315", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030315", "evidence": [ { "database": "UniProtKB", "id": "F1M107", "url": "https://www.uniprot.org/uniprotkb/F1M107" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1M107", "url": "https://www.uniprot.org/uniprotkb/F1M107" } ], "pmid": "" }, { "name": "transmembrane transporter binding", "id": "GO:0044325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044325", "evidence": [ { "database": "UniProtKB", "id": "F1M107", "url": "https://www.uniprot.org/uniprotkb/F1M107" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1M107-1" }, { "uniprot_canonical_ac": "F1M287-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1M287", "url": "https://www.uniprot.org/uniprotkb/F1M287" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1085, "chemical_mass": 124038.0, "gene_names": "Srgap1;RGD1566260;Srgap1", "protein_name": "SLIT-ROBO Rho GTPase-activating protein 1", "disease": [ { "disease_id": "DOID:1312", "name": "focal segmental glomerulosclerosis", "description": "", "url": "https://disease-ontology.org/term/DOID:1312", "evidence": [ { "id": "1312", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1312" } ], "weight": 0.0 }, { "disease_id": "DOID:3969", "name": "papillary thyroid carcinoma", "description": "A differentiated thyroid gland carcinoma that is characterized by the small mushroom shape of the tumor which has a stem attached to the epithelial layer and arises from the follicular cells of the thyroid gland.", "url": "https://disease-ontology.org/term/DOID:3969", "evidence": [ { "id": "3969", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3969" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "F1M287", "url": "https://www.uniprot.org/uniprotkb/F1M287" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "F1M287", "url": "https://www.uniprot.org/uniprotkb/F1M287" } ], "pmid": "" } ], "biological_process": [ { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "F1M287", "url": "https://www.uniprot.org/uniprotkb/F1M287" } ], "pmid": "" }, { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "F1M287", "url": "https://www.uniprot.org/uniprotkb/F1M287" } ], "pmid": "" }, { "name": "negative regulation of cell migration", "id": "GO:0030336", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030336", "evidence": [ { "database": "UniProtKB", "id": "F1M287", "url": "https://www.uniprot.org/uniprotkb/F1M287" } ], "pmid": "" }, { "name": "Rho protein signal transduction", "id": "GO:0007266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007266", "evidence": [ { "database": "UniProtKB", "id": "F1M287", "url": "https://www.uniprot.org/uniprotkb/F1M287" } ], "pmid": "" }, { "name": "regulation of synapse assembly", "id": "GO:0051963", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051963", "evidence": [ { "database": "UniProtKB", "id": "F1M287", "url": "https://www.uniprot.org/uniprotkb/F1M287" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "F1M287", "url": "https://www.uniprot.org/uniprotkb/F1M287" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "F1M287-1", "start_pos": "1001", "end_pos": "1001", "site_lbl": "Thr1001", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1001, "start_aa": "Thr", "end_pos": 1001, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1001", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "F1M287-1" }, { "uniprot_canonical_ac": "F1M2I1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1M2I1", "url": "https://www.uniprot.org/uniprotkb/F1M2I1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 893, "chemical_mass": 102276.0, "gene_names": "Mroh9", "protein_name": "", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1M2I1", "url": "https://www.uniprot.org/uniprotkb/F1M2I1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1M2I1-1" }, { "uniprot_canonical_ac": "F1M2K6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1M2K6", "url": "https://www.uniprot.org/uniprotkb/F1M2K6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1146, "chemical_mass": 127018.0, "gene_names": "Pkp4", "protein_name": "", "disease": [ { "disease_id": "DOID:0060041", "name": "autism spectrum disorder", "description": "A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior.", "url": "https://disease-ontology.org/term/DOID:0060041", "evidence": [ { "id": "0060041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060041" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "spindle pole", "id": "GO:0000922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000922", "evidence": [ { "database": "UniProtKB", "id": "F1M2K6", "url": "https://www.uniprot.org/uniprotkb/F1M2K6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1M2K6", "url": "https://www.uniprot.org/uniprotkb/F1M2K6" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "F1M2K6", "url": "https://www.uniprot.org/uniprotkb/F1M2K6" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1M2K6", "url": "https://www.uniprot.org/uniprotkb/F1M2K6" } ], "pmid": "" }, { "name": "cell-cell junction", "id": "GO:0005911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005911", "evidence": [ { "database": "UniProtKB", "id": "F1M2K6", "url": "https://www.uniprot.org/uniprotkb/F1M2K6" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "F1M2K6", "url": "https://www.uniprot.org/uniprotkb/F1M2K6" } ], "pmid": "" }, { "name": "cell junction", "id": "GO:0030054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030054", "evidence": [ { "database": "UniProtKB", "id": "F1M2K6", "url": "https://www.uniprot.org/uniprotkb/F1M2K6" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "F1M2K6", "url": "https://www.uniprot.org/uniprotkb/F1M2K6" } ], "pmid": "" }, { "name": "spindle midzone", "id": "GO:0051233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051233", "evidence": [ { "database": "UniProtKB", "id": "F1M2K6", "url": "https://www.uniprot.org/uniprotkb/F1M2K6" } ], "pmid": "" }, { "name": "cytoplasmic side of plasma membrane", "id": "GO:0009898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009898", "evidence": [ { "database": "UniProtKB", "id": "F1M2K6", "url": "https://www.uniprot.org/uniprotkb/F1M2K6" } ], "pmid": "" }, { "name": "midbody", "id": "GO:0030496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030496", "evidence": [ { "database": "UniProtKB", "id": "F1M2K6", "url": "https://www.uniprot.org/uniprotkb/F1M2K6" } ], "pmid": "" }, { "name": "cell-cell contact zone", "id": "GO:0044291", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044291", "evidence": [ { "database": "UniProtKB", "id": "F1M2K6", "url": "https://www.uniprot.org/uniprotkb/F1M2K6" } ], "pmid": "" }, { "name": "mitotic spindle", "id": "GO:0072686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072686", "evidence": [ { "database": "UniProtKB", "id": "F1M2K6", "url": "https://www.uniprot.org/uniprotkb/F1M2K6" } ], "pmid": "" }, { "name": "desmosome", "id": "GO:0030057", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030057", "evidence": [ { "database": "UniProtKB", "id": "F1M2K6", "url": "https://www.uniprot.org/uniprotkb/F1M2K6" } ], "pmid": "" } ], "biological_process": [ { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "F1M2K6", "url": "https://www.uniprot.org/uniprotkb/F1M2K6" } ], "pmid": "" }, { "name": "regulation of Rho protein signal transduction", "id": "GO:0035023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035023", "evidence": [ { "database": "UniProtKB", "id": "F1M2K6", "url": "https://www.uniprot.org/uniprotkb/F1M2K6" } ], "pmid": "" }, { "name": "cell-cell junction assembly", "id": "GO:0007043", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007043", "evidence": [ { "database": "UniProtKB", "id": "F1M2K6", "url": "https://www.uniprot.org/uniprotkb/F1M2K6" } ], "pmid": "" }, { "name": "positive regulation of cytokinesis", "id": "GO:0032467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032467", "evidence": [ { "database": "UniProtKB", "id": "F1M2K6", "url": "https://www.uniprot.org/uniprotkb/F1M2K6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1M2K6-1" }, { "uniprot_canonical_ac": "F1M3X3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1M3X3", "url": "https://www.uniprot.org/uniprotkb/F1M3X3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 98, "chemical_mass": 10834.0, "gene_names": "ENSRNOG00000068908", "protein_name": "Ig-like domain-containing protein", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "F1M3X3", "url": "https://www.uniprot.org/uniprotkb/F1M3X3" } ], "pmid": "" }, { "name": "immunoglobulin complex", "id": "GO:0019814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019814", "evidence": [ { "database": "UniProtKB", "id": "F1M3X3", "url": "https://www.uniprot.org/uniprotkb/F1M3X3" } ], "pmid": "" } ], "molecular_function": [ { "name": "antigen binding", "id": "GO:0003823", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003823", "evidence": [ { "database": "UniProtKB", "id": "F1M3X3", "url": "https://www.uniprot.org/uniprotkb/F1M3X3" } ], "pmid": "" } ], "biological_process": [ { "name": "immunoglobulin mediated immune response", "id": "GO:0016064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016064", "evidence": [ { "database": "UniProtKB", "id": "F1M3X3", "url": "https://www.uniprot.org/uniprotkb/F1M3X3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1M3X3-1" }, { "uniprot_canonical_ac": "F1M3X5-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1M3X5", "url": "https://www.uniprot.org/uniprotkb/F1M3X5" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 720, "chemical_mass": 78006.0, "gene_names": "Mroh6;LOC100359562;Mroh6", "protein_name": "", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1M3X5", "url": "https://www.uniprot.org/uniprotkb/F1M3X5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "F1M3X5-1", "start_pos": "75", "end_pos": "75", "site_lbl": "Thr75", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 75, "start_aa": "Thr", "end_pos": 75, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr75", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "F1M3X5-1" }, { "uniprot_canonical_ac": "F1M419-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1M419", "url": "https://www.uniprot.org/uniprotkb/F1M419" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 370, "chemical_mass": 39990.0, "gene_names": "Pim2", "protein_name": "Serine/threonine-protein kinase pim-2", "disease": [], "molecular_function": [ { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "F1M419", "url": "https://www.uniprot.org/uniprotkb/F1M419" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "F1M419", "url": "https://www.uniprot.org/uniprotkb/F1M419" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1M419", "url": "https://www.uniprot.org/uniprotkb/F1M419" } ], "pmid": "" }, { "name": "protein serine kinase activity", "id": "GO:0106310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106310", "evidence": [ { "database": "UniProtKB", "id": "F1M419", "url": "https://www.uniprot.org/uniprotkb/F1M419" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1M419", "url": "https://www.uniprot.org/uniprotkb/F1M419" } ], "pmid": "" } ], "biological_process": [ { "name": "protein phosphorylation", "id": "GO:0006468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006468", "evidence": [ { "database": "UniProtKB", "id": "F1M419", "url": "https://www.uniprot.org/uniprotkb/F1M419" } ], "pmid": "" }, { "name": "negative regulation of cell population proliferation", "id": "GO:0008285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008285", "evidence": [ { "database": "UniProtKB", "id": "F1M419", "url": "https://www.uniprot.org/uniprotkb/F1M419" } ], "pmid": "" }, { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "F1M419", "url": "https://www.uniprot.org/uniprotkb/F1M419" } ], "pmid": "" }, { "name": "regulation of mitotic cell cycle", "id": "GO:0007346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007346", "evidence": [ { "database": "UniProtKB", "id": "F1M419", "url": "https://www.uniprot.org/uniprotkb/F1M419" } ], "pmid": "" }, { "name": "response to virus", "id": "GO:0009615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009615", "evidence": [ { "database": "UniProtKB", "id": "F1M419", "url": "https://www.uniprot.org/uniprotkb/F1M419" } ], "pmid": "" }, { "name": "positive regulation of canonical NF-kappaB signal transduction", "id": "GO:0043123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043123", "evidence": [ { "database": "UniProtKB", "id": "F1M419", "url": "https://www.uniprot.org/uniprotkb/F1M419" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "F1M419", "url": "https://www.uniprot.org/uniprotkb/F1M419" } ], "pmid": "" }, { "name": "protein stabilization", "id": "GO:0050821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050821", "evidence": [ { "database": "UniProtKB", "id": "F1M419", "url": "https://www.uniprot.org/uniprotkb/F1M419" } ], "pmid": "" }, { "name": "positive regulation of autophagy", "id": "GO:0010508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010508", "evidence": [ { "database": "UniProtKB", "id": "F1M419", "url": "https://www.uniprot.org/uniprotkb/F1M419" } ], "pmid": "" }, { "name": "G1/S transition of mitotic cell cycle", "id": "GO:0000082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000082", "evidence": [ { "database": "UniProtKB", "id": "F1M419", "url": "https://www.uniprot.org/uniprotkb/F1M419" } ], "pmid": "" }, { "name": "positive regulation of macroautophagy", "id": "GO:0016239", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016239", "evidence": [ { "database": "UniProtKB", "id": "F1M419", "url": "https://www.uniprot.org/uniprotkb/F1M419" } ], "pmid": "" }, { "name": "apoptotic mitochondrial changes", "id": "GO:0008637", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008637", "evidence": [ { "database": "UniProtKB", "id": "F1M419", "url": "https://www.uniprot.org/uniprotkb/F1M419" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "F1M419-1", "start_pos": "76", "end_pos": "76", "site_lbl": "Thr76", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 76, "start_aa": "Thr", "end_pos": 76, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr76", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "F1M419-1" }, { "uniprot_canonical_ac": "F1M478-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1M478", "url": "https://www.uniprot.org/uniprotkb/F1M478" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 240, "chemical_mass": 27015.0, "gene_names": "Isx;Isx;LOC682968", "protein_name": "Intestine-specific homeobox", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1M478", "url": "https://www.uniprot.org/uniprotkb/F1M478" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1M478", "url": "https://www.uniprot.org/uniprotkb/F1M478" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "F1M478", "url": "https://www.uniprot.org/uniprotkb/F1M478" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1M478", "url": "https://www.uniprot.org/uniprotkb/F1M478" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "F1M478", "url": "https://www.uniprot.org/uniprotkb/F1M478" } ], "pmid": "" }, { "name": "neuron development", "id": "GO:0048666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048666", "evidence": [ { "database": "UniProtKB", "id": "F1M478", "url": "https://www.uniprot.org/uniprotkb/F1M478" } ], "pmid": "" }, { "name": "negative regulation of intestinal absorption", "id": "GO:1904479", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904479", "evidence": [ { "database": "UniProtKB", "id": "F1M478", "url": "https://www.uniprot.org/uniprotkb/F1M478" } ], "pmid": "" }, { "name": "regulation of vitamin A metabolic process", "id": "GO:1901738", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901738", "evidence": [ { "database": "UniProtKB", "id": "F1M478", "url": "https://www.uniprot.org/uniprotkb/F1M478" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "F1M478", "url": "https://www.uniprot.org/uniprotkb/F1M478" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "F1M478", "url": "https://www.uniprot.org/uniprotkb/F1M478" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "F1M478", "url": "https://www.uniprot.org/uniprotkb/F1M478" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "F1M478", "url": "https://www.uniprot.org/uniprotkb/F1M478" } ], "pmid": "" }, { "name": "sequence-specific double-stranded DNA binding", "id": "GO:1990837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990837", "evidence": [ { "database": "UniProtKB", "id": "F1M478", "url": "https://www.uniprot.org/uniprotkb/F1M478" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1M478-1" }, { "uniprot_canonical_ac": "F1M4E3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1M4E3", "url": "https://www.uniprot.org/uniprotkb/F1M4E3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 476, "chemical_mass": 51333.0, "gene_names": "Mfsd12", "protein_name": "Major facilitator superfamily domain-containing protein 12", "disease": [], "biological_process": [ { "name": "negative regulation of melanin biosynthetic process", "id": "GO:0048022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048022", "evidence": [ { "database": "UniProtKB", "id": "F1M4E3", "url": "https://www.uniprot.org/uniprotkb/F1M4E3" } ], "pmid": "" }, { "name": "carbohydrate transport", "id": "GO:0008643", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008643", "evidence": [ { "database": "UniProtKB", "id": "F1M4E3", "url": "https://www.uniprot.org/uniprotkb/F1M4E3" } ], "pmid": "" }, { "name": "melanin biosynthetic process", "id": "GO:0042438", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042438", "evidence": [ { "database": "UniProtKB", "id": "F1M4E3", "url": "https://www.uniprot.org/uniprotkb/F1M4E3" } ], "pmid": "" }, { "name": "cysteine transmembrane transport", "id": "GO:1903712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903712", "evidence": [ { "database": "UniProtKB", "id": "F1M4E3", "url": "https://www.uniprot.org/uniprotkb/F1M4E3" } ], "pmid": "" }, { "name": "regulation of melanin biosynthetic process", "id": "GO:0048021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048021", "evidence": [ { "database": "UniProtKB", "id": "F1M4E3", "url": "https://www.uniprot.org/uniprotkb/F1M4E3" } ], "pmid": "" }, { "name": "pigment metabolic process involved in pigmentation", "id": "GO:0043474", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043474", "evidence": [ { "database": "UniProtKB", "id": "F1M4E3", "url": "https://www.uniprot.org/uniprotkb/F1M4E3" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1M4E3", "url": "https://www.uniprot.org/uniprotkb/F1M4E3" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "F1M4E3", "url": "https://www.uniprot.org/uniprotkb/F1M4E3" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "F1M4E3", "url": "https://www.uniprot.org/uniprotkb/F1M4E3" } ], "pmid": "" }, { "name": "melanosome", "id": "GO:0042470", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042470", "evidence": [ { "database": "UniProtKB", "id": "F1M4E3", "url": "https://www.uniprot.org/uniprotkb/F1M4E3" } ], "pmid": "" }, { "name": "late endosome", "id": "GO:0005770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005770", "evidence": [ { "database": "UniProtKB", "id": "F1M4E3", "url": "https://www.uniprot.org/uniprotkb/F1M4E3" } ], "pmid": "" }, { "name": "melanosome membrane", "id": "GO:0033162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033162", "evidence": [ { "database": "UniProtKB", "id": "F1M4E3", "url": "https://www.uniprot.org/uniprotkb/F1M4E3" } ], "pmid": "" } ], "molecular_function": [ { "name": "symporter activity", "id": "GO:0015293", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015293", "evidence": [ { "database": "UniProtKB", "id": "F1M4E3", "url": "https://www.uniprot.org/uniprotkb/F1M4E3" } ], "pmid": "" }, { "name": "cysteine transmembrane transporter activity", "id": "GO:0033229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033229", "evidence": [ { "database": "UniProtKB", "id": "F1M4E3", "url": "https://www.uniprot.org/uniprotkb/F1M4E3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1M4E3-1" }, { "uniprot_canonical_ac": "F1M4I4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1M4I4", "url": "https://www.uniprot.org/uniprotkb/F1M4I4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 782, "chemical_mass": 86145.0, "gene_names": "Vps51;RGD1560544;Vps51", "protein_name": "Vacuolar protein sorting-associated protein 51 homolog", "disease": [ { "disease_id": "DOID:0112332", "name": "pontocerebellar hypoplasia type 13", "description": "A pontocerebellar hypoplasia characterized by global developmental delay, impaired intellectual development with absent speech, microcephaly, and progressive atrophy of the cerebellar vermis and brainstem that has_material_basis_in homozygous or compound heterozygous mutation in the VPS51 gene on chromosome 11q13.1.", "url": "https://disease-ontology.org/term/DOID:0112332", "evidence": [ { "id": "0112332", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112332" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "GARP complex", "id": "GO:0000938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000938", "evidence": [ { "database": "UniProtKB", "id": "F1M4I4", "url": "https://www.uniprot.org/uniprotkb/F1M4I4" } ], "pmid": "" }, { "name": "EARP complex", "id": "GO:1990745", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990745", "evidence": [ { "database": "UniProtKB", "id": "F1M4I4", "url": "https://www.uniprot.org/uniprotkb/F1M4I4" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "F1M4I4", "url": "https://www.uniprot.org/uniprotkb/F1M4I4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1M4I4", "url": "https://www.uniprot.org/uniprotkb/F1M4I4" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1M4I4", "url": "https://www.uniprot.org/uniprotkb/F1M4I4" } ], "pmid": "" }, { "name": "recycling endosome", "id": "GO:0055037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055037", "evidence": [ { "database": "UniProtKB", "id": "F1M4I4", "url": "https://www.uniprot.org/uniprotkb/F1M4I4" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "F1M4I4", "url": "https://www.uniprot.org/uniprotkb/F1M4I4" } ], "pmid": "" } ], "biological_process": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "F1M4I4", "url": "https://www.uniprot.org/uniprotkb/F1M4I4" } ], "pmid": "" }, { "name": "protein targeting", "id": "GO:0006605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006605", "evidence": [ { "database": "UniProtKB", "id": "F1M4I4", "url": "https://www.uniprot.org/uniprotkb/F1M4I4" } ], "pmid": "" }, { "name": "autophagy", "id": "GO:0006914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006914", "evidence": [ { "database": "UniProtKB", "id": "F1M4I4", "url": "https://www.uniprot.org/uniprotkb/F1M4I4" } ], "pmid": "" }, { "name": "retrograde transport, endosome to Golgi", "id": "GO:0042147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042147", "evidence": [ { "database": "UniProtKB", "id": "F1M4I4", "url": "https://www.uniprot.org/uniprotkb/F1M4I4" } ], "pmid": "" }, { "name": "brain morphogenesis", "id": "GO:0048854", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048854", "evidence": [ { "database": "UniProtKB", "id": "F1M4I4", "url": "https://www.uniprot.org/uniprotkb/F1M4I4" } ], "pmid": "" }, { "name": "Golgi organization", "id": "GO:0007030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007030", "evidence": [ { "database": "UniProtKB", "id": "F1M4I4", "url": "https://www.uniprot.org/uniprotkb/F1M4I4" } ], "pmid": "" }, { "name": "endocytic recycling", "id": "GO:0032456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032456", "evidence": [ { "database": "UniProtKB", "id": "F1M4I4", "url": "https://www.uniprot.org/uniprotkb/F1M4I4" } ], "pmid": "" }, { "name": "Golgi vesicle transport", "id": "GO:0048193", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048193", "evidence": [ { "database": "UniProtKB", "id": "F1M4I4", "url": "https://www.uniprot.org/uniprotkb/F1M4I4" } ], "pmid": "" }, { "name": "lysosomal transport", "id": "GO:0007041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007041", "evidence": [ { "database": "UniProtKB", "id": "F1M4I4", "url": "https://www.uniprot.org/uniprotkb/F1M4I4" } ], "pmid": "" }, { "name": "vesicle-mediated cholesterol transport", "id": "GO:0090119", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090119", "evidence": [ { "database": "UniProtKB", "id": "F1M4I4", "url": "https://www.uniprot.org/uniprotkb/F1M4I4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "F1M4I4-1", "start_pos": "559", "end_pos": "559", "site_lbl": "Thr559", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 559, "start_aa": "Thr", "end_pos": 559, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr559", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "F1M4I4-1" }, { "uniprot_canonical_ac": "F1M4K0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1M4K0", "url": "https://www.uniprot.org/uniprotkb/F1M4K0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 484, "chemical_mass": 51205.0, "gene_names": "Shf;RGD1562705;Shf", "protein_name": "", "disease": [], "molecular_function": [ { "name": "phosphotyrosine residue binding", "id": "GO:0001784", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001784", "evidence": [ { "database": "UniProtKB", "id": "F1M4K0", "url": "https://www.uniprot.org/uniprotkb/F1M4K0" } ], "pmid": "" } ], "biological_process": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "F1M4K0", "url": "https://www.uniprot.org/uniprotkb/F1M4K0" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "F1M4K0", "url": "https://www.uniprot.org/uniprotkb/F1M4K0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "F1M4K0-1", "start_pos": "127", "end_pos": "127", "site_lbl": "Thr127", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 127, "start_aa": "Thr", "end_pos": 127, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr127", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "F1M4K0-1" }, { "uniprot_canonical_ac": "F1M541-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1M541", "url": "https://www.uniprot.org/uniprotkb/F1M541" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 287, "chemical_mass": 31205.0, "gene_names": "Pou2af2;Pou2af2;RGD1562914", "protein_name": "", "disease": [], "molecular_function": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "F1M541", "url": "https://www.uniprot.org/uniprotkb/F1M541" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "F1M541", "url": "https://www.uniprot.org/uniprotkb/F1M541" } ], "pmid": "" }, { "name": "POU domain binding", "id": "GO:0070974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070974", "evidence": [ { "database": "UniProtKB", "id": "F1M541", "url": "https://www.uniprot.org/uniprotkb/F1M541" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1M541", "url": "https://www.uniprot.org/uniprotkb/F1M541" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1M541", "url": "https://www.uniprot.org/uniprotkb/F1M541" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "F1M541-1", "start_pos": "127", "end_pos": "127", "site_lbl": "Thr127", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 127, "start_aa": "Thr", "end_pos": 127, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr127", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "F1M541-1", "start_pos": "229", "end_pos": "229", "site_lbl": "Thr229", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 229, "start_aa": "Thr", "end_pos": 229, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr229", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "F1M541-1" }, { "uniprot_canonical_ac": "F1M5N0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1M5N0", "url": "https://www.uniprot.org/uniprotkb/F1M5N0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 314, "chemical_mass": 34906.0, "gene_names": "Or52b1;Olr201;Or52b1;ratchr1-163166306-163165362_ORF", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "F1M5N0", "url": "https://www.uniprot.org/uniprotkb/F1M5N0" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "F1M5N0", "url": "https://www.uniprot.org/uniprotkb/F1M5N0" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1M5N0", "url": "https://www.uniprot.org/uniprotkb/F1M5N0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1M5N0-1" }, { "uniprot_canonical_ac": "F1M5Q3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1M5Q3", "url": "https://www.uniprot.org/uniprotkb/F1M5Q3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 263, "chemical_mass": 28608.0, "gene_names": "Kctd2;Kctd2;RGD1566063", "protein_name": "", "disease": [ { "disease_id": "DOID:0090033", "name": "myoclonic dystonia", "description": "A dystonia that is characterized by myoclonic jerks affecting mostly proximal muscles and dystonia, usually torticollis or writer's cramp, that typically responds to alcohol and has onset in the first or second decade of life.", "url": "https://disease-ontology.org/term/DOID:0090033", "evidence": [ { "id": "0090033", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0090033" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1M5Q3", "url": "https://www.uniprot.org/uniprotkb/F1M5Q3" } ], "pmid": "" }, { "name": "Cul3-RING ubiquitin ligase complex", "id": "GO:0031463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031463", "evidence": [ { "database": "UniProtKB", "id": "F1M5Q3", "url": "https://www.uniprot.org/uniprotkb/F1M5Q3" } ], "pmid": "" } ], "biological_process": [ { "name": "protein homooligomerization", "id": "GO:0051260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051260", "evidence": [ { "database": "UniProtKB", "id": "F1M5Q3", "url": "https://www.uniprot.org/uniprotkb/F1M5Q3" } ], "pmid": "" }, { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "F1M5Q3", "url": "https://www.uniprot.org/uniprotkb/F1M5Q3" } ], "pmid": "" } ], "molecular_function": [ { "name": "cullin family protein binding", "id": "GO:0097602", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097602", "evidence": [ { "database": "UniProtKB", "id": "F1M5Q3", "url": "https://www.uniprot.org/uniprotkb/F1M5Q3" } ], "pmid": "" }, { "name": "protein-containing complex binding", "id": "GO:0044877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044877", "evidence": [ { "database": "UniProtKB", "id": "F1M5Q3", "url": "https://www.uniprot.org/uniprotkb/F1M5Q3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "F1M5Q3-1", "start_pos": "40", "end_pos": "40", "site_lbl": "Thr40", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 40, "start_aa": "Thr", "end_pos": 40, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr40", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "F1M5Q3-1" }, { "uniprot_canonical_ac": "F1M5V3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1M5V3", "url": "https://www.uniprot.org/uniprotkb/F1M5V3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 64, "chemical_mass": 7664.0, "gene_names": "LOC120094817", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1M5V3", "url": "https://www.uniprot.org/uniprotkb/F1M5V3" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1M5V3", "url": "https://www.uniprot.org/uniprotkb/F1M5V3" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "F1M5V3", "url": "https://www.uniprot.org/uniprotkb/F1M5V3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1M5V3-1" }, { "uniprot_canonical_ac": "F1M5Y6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1M5Y6", "url": "https://www.uniprot.org/uniprotkb/F1M5Y6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 430, "chemical_mass": 48279.0, "gene_names": "Triml2;RGD1565382;Triml2", "protein_name": "", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1M5Y6", "url": "https://www.uniprot.org/uniprotkb/F1M5Y6" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1M5Y6", "url": "https://www.uniprot.org/uniprotkb/F1M5Y6" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "F1M5Y6", "url": "https://www.uniprot.org/uniprotkb/F1M5Y6" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "F1M5Y6", "url": "https://www.uniprot.org/uniprotkb/F1M5Y6" } ], "pmid": "" } ], "biological_process": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "F1M5Y6", "url": "https://www.uniprot.org/uniprotkb/F1M5Y6" } ], "pmid": "" }, { "name": "response to retinoic acid", "id": "GO:0032526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032526", "evidence": [ { "database": "UniProtKB", "id": "F1M5Y6", "url": "https://www.uniprot.org/uniprotkb/F1M5Y6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1M5Y6-1" }, { "uniprot_canonical_ac": "F1M632-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1M632", "url": "https://www.uniprot.org/uniprotkb/F1M632" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1889, "chemical_mass": 218678.0, "gene_names": "Ak9;Ak9;Akd2;RGD1559879;RGD1560386", "protein_name": "Adenylate kinase 9", "disease": [ { "disease_id": "DOID:0070588", "name": "spermatogenic failure 89", "description": "A spermatogenic failure characterized by severely reduced progressive motility of sperm that has_material_basis_in homozygous or compound heterozygous mutation in the AK9 gene on chromosome 6q21.", "url": "https://disease-ontology.org/term/DOID:0070588", "evidence": [ { "id": "0070588", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070588" } ], "weight": 0.0 }, { "disease_id": "DOID:1572", "name": "normal pressure hydrocephalus", "description": "A communicating hydrocephalus characterized by normal cerebrospinal fluid pressure, gait instability, cognitive decline, and impaired bladder control. Onset is usually in late adulthood.", "url": "https://disease-ontology.org/term/DOID:1572", "evidence": [ { "id": "1572", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1572" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "nucleoside monophosphate kinase activity", "id": "GO:0050145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050145", "evidence": [ { "database": "UniProtKB", "id": "F1M632", "url": "https://www.uniprot.org/uniprotkb/F1M632" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1M632", "url": "https://www.uniprot.org/uniprotkb/F1M632" } ], "pmid": "" }, { "name": "nucleoside diphosphate kinase activity", "id": "GO:0004550", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004550", "evidence": [ { "database": "UniProtKB", "id": "F1M632", "url": "https://www.uniprot.org/uniprotkb/F1M632" } ], "pmid": "" }, { "name": "UMP kinase activity", "id": "GO:0033862", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033862", "evidence": [ { "database": "UniProtKB", "id": "F1M632", "url": "https://www.uniprot.org/uniprotkb/F1M632" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1M632", "url": "https://www.uniprot.org/uniprotkb/F1M632" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1M632", "url": "https://www.uniprot.org/uniprotkb/F1M632" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1M632", "url": "https://www.uniprot.org/uniprotkb/F1M632" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1M632", "url": "https://www.uniprot.org/uniprotkb/F1M632" } ], "pmid": "" }, { "name": "motile cilium", "id": "GO:0031514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031514", "evidence": [ { "database": "UniProtKB", "id": "F1M632", "url": "https://www.uniprot.org/uniprotkb/F1M632" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "F1M632", "url": "https://www.uniprot.org/uniprotkb/F1M632" } ], "pmid": "" } ], "biological_process": [ { "name": "UDP biosynthetic process", "id": "GO:0006225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006225", "evidence": [ { "database": "UniProtKB", "id": "F1M632", "url": "https://www.uniprot.org/uniprotkb/F1M632" } ], "pmid": "" }, { "name": "CDP biosynthetic process", "id": "GO:0046705", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046705", "evidence": [ { "database": "UniProtKB", "id": "F1M632", "url": "https://www.uniprot.org/uniprotkb/F1M632" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "F1M632-1", "start_pos": "1481", "end_pos": "1481", "site_lbl": "Thr1481", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1481, "start_aa": "Thr", "end_pos": 1481, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1481", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "F1M632-1" }, { "uniprot_canonical_ac": "F1M6N1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1M6N1", "url": "https://www.uniprot.org/uniprotkb/F1M6N1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 544, "chemical_mass": 65089.0, "gene_names": "Zfp945l1;LOC682225;Zfp945l1", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1M6N1", "url": "https://www.uniprot.org/uniprotkb/F1M6N1" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1M6N1", "url": "https://www.uniprot.org/uniprotkb/F1M6N1" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "F1M6N1", "url": "https://www.uniprot.org/uniprotkb/F1M6N1" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1M6N1", "url": "https://www.uniprot.org/uniprotkb/F1M6N1" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "F1M6N1", "url": "https://www.uniprot.org/uniprotkb/F1M6N1" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "F1M6N1", "url": "https://www.uniprot.org/uniprotkb/F1M6N1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1M6N1-1" }, { "uniprot_canonical_ac": "F1M6U5-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1M6U5", "url": "https://www.uniprot.org/uniprotkb/F1M6U5" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 290, "chemical_mass": 31452.0, "gene_names": "Asb9;Asb9;RGD1560537", "protein_name": "", "disease": [], "biological_process": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "F1M6U5", "url": "https://www.uniprot.org/uniprotkb/F1M6U5" } ], "pmid": "" }, { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "F1M6U5", "url": "https://www.uniprot.org/uniprotkb/F1M6U5" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "F1M6U5", "url": "https://www.uniprot.org/uniprotkb/F1M6U5" } ], "pmid": "" }, { "name": "positive regulation of protein catabolic process", "id": "GO:0045732", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045732", "evidence": [ { "database": "UniProtKB", "id": "F1M6U5", "url": "https://www.uniprot.org/uniprotkb/F1M6U5" } ], "pmid": "" } ], "cellular_component": [ { "name": "Cul5-RING ubiquitin ligase complex", "id": "GO:0031466", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031466", "evidence": [ { "database": "UniProtKB", "id": "F1M6U5", "url": "https://www.uniprot.org/uniprotkb/F1M6U5" } ], "pmid": "" } ], "molecular_function": [ { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "F1M6U5", "url": "https://www.uniprot.org/uniprotkb/F1M6U5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1M6U5-1" }, { "uniprot_canonical_ac": "F1M7J7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1M7J7", "url": "https://www.uniprot.org/uniprotkb/F1M7J7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 2428, "chemical_mass": 278624.0, "gene_names": "Cep250;Cep250;RGD1562262", "protein_name": "", "disease": [ { "disease_id": "DOID:10584", "name": "retinitis pigmentosa", "description": "A retinal degeneration characterized by the gradual deterioration of the photoreceptors or the retinal pigment epithelium of the retina leading to progressive sight loss.", "url": "https://disease-ontology.org/term/DOID:10584", "evidence": [ { "id": "10584", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10584" } ], "weight": 0.0 } ], "biological_process": [ { "name": "regulation of centriole-centriole cohesion", "id": "GO:0030997", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030997", "evidence": [ { "database": "UniProtKB", "id": "F1M7J7", "url": "https://www.uniprot.org/uniprotkb/F1M7J7" } ], "pmid": "" }, { "name": "mitotic cell cycle", "id": "GO:0000278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000278", "evidence": [ { "database": "UniProtKB", "id": "F1M7J7", "url": "https://www.uniprot.org/uniprotkb/F1M7J7" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "F1M7J7", "url": "https://www.uniprot.org/uniprotkb/F1M7J7" } ], "pmid": "" }, { "name": "intracellular protein localization", "id": "GO:0008104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008104", "evidence": [ { "database": "UniProtKB", "id": "F1M7J7", "url": "https://www.uniprot.org/uniprotkb/F1M7J7" } ], "pmid": "" }, { "name": "positive regulation of protein localization to centrosome", "id": "GO:1904781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904781", "evidence": [ { "database": "UniProtKB", "id": "F1M7J7", "url": "https://www.uniprot.org/uniprotkb/F1M7J7" } ], "pmid": "" }, { "name": "non-motile cilium assembly", "id": "GO:1905515", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905515", "evidence": [ { "database": "UniProtKB", "id": "F1M7J7", "url": "https://www.uniprot.org/uniprotkb/F1M7J7" } ], "pmid": "" }, { "name": "detection of light stimulus involved in visual perception", "id": "GO:0050908", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050908", "evidence": [ { "database": "UniProtKB", "id": "F1M7J7", "url": "https://www.uniprot.org/uniprotkb/F1M7J7" } ], "pmid": "" }, { "name": "protein localization to centrosome", "id": "GO:0071539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071539", "evidence": [ { "database": "UniProtKB", "id": "F1M7J7", "url": "https://www.uniprot.org/uniprotkb/F1M7J7" } ], "pmid": "" }, { "name": "centriole-centriole cohesion", "id": "GO:0010457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010457", "evidence": [ { "database": "UniProtKB", "id": "F1M7J7", "url": "https://www.uniprot.org/uniprotkb/F1M7J7" } ], "pmid": "" } ], "cellular_component": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "F1M7J7", "url": "https://www.uniprot.org/uniprotkb/F1M7J7" } ], "pmid": "" }, { "name": "photoreceptor inner segment", "id": "GO:0001917", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001917", "evidence": [ { "database": "UniProtKB", "id": "F1M7J7", "url": "https://www.uniprot.org/uniprotkb/F1M7J7" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "F1M7J7", "url": "https://www.uniprot.org/uniprotkb/F1M7J7" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "F1M7J7", "url": "https://www.uniprot.org/uniprotkb/F1M7J7" } ], "pmid": "" }, { "name": "photoreceptor outer segment", "id": "GO:0001750", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001750", "evidence": [ { "database": "UniProtKB", "id": "F1M7J7", "url": "https://www.uniprot.org/uniprotkb/F1M7J7" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "F1M7J7", "url": "https://www.uniprot.org/uniprotkb/F1M7J7" } ], "pmid": "" }, { "name": "spindle pole centrosome", "id": "GO:0031616", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031616", "evidence": [ { "database": "UniProtKB", "id": "F1M7J7", "url": "https://www.uniprot.org/uniprotkb/F1M7J7" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein domain specific binding", "id": "GO:0019904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019904", "evidence": [ { "database": "UniProtKB", "id": "F1M7J7", "url": "https://www.uniprot.org/uniprotkb/F1M7J7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1M7J7-1" }, { "uniprot_canonical_ac": "F1M834-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1M834", "url": "https://www.uniprot.org/uniprotkb/F1M834" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 308, "chemical_mass": 34386.0, "gene_names": "", "protein_name": "", "disease": [], "biological_process": [ { "name": "retrotransposition", "id": "GO:0032197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032197", "evidence": [ { "database": "UniProtKB", "id": "F1M834", "url": "https://www.uniprot.org/uniprotkb/F1M834" } ], "pmid": "" } ], "molecular_function": [ { "name": "single-stranded RNA binding", "id": "GO:0003727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003727", "evidence": [ { "database": "UniProtKB", "id": "F1M834", "url": "https://www.uniprot.org/uniprotkb/F1M834" } ], "pmid": "" } ], "cellular_component": [ { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "F1M834", "url": "https://www.uniprot.org/uniprotkb/F1M834" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1M834-1" }, { "uniprot_canonical_ac": "F1M897-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1M897", "url": "https://www.uniprot.org/uniprotkb/F1M897" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1613, "chemical_mass": 159766.0, "gene_names": "Col22a1;Col22a1", "protein_name": "", "disease": [ { "disease_id": "DOID:10941", "name": "intracranial aneurysm", "description": "", "url": "https://disease-ontology.org/term/DOID:10941", "evidence": [ { "id": "10941", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10941" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "F1M897", "url": "https://www.uniprot.org/uniprotkb/F1M897" } ], "pmid": "" }, { "name": "basement membrane", "id": "GO:0005604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005604", "evidence": [ { "database": "UniProtKB", "id": "F1M897", "url": "https://www.uniprot.org/uniprotkb/F1M897" } ], "pmid": "" } ], "biological_process": [ { "name": "extracellular matrix organization", "id": "GO:0030198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030198", "evidence": [ { "database": "UniProtKB", "id": "F1M897", "url": "https://www.uniprot.org/uniprotkb/F1M897" } ], "pmid": "" } ], "molecular_function": [ { "name": "extracellular matrix structural constituent conferring tensile strength", "id": "GO:0030020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030020", "evidence": [ { "database": "UniProtKB", "id": "F1M897", "url": "https://www.uniprot.org/uniprotkb/F1M897" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "F1M897-1", "start_pos": "1069", "end_pos": "1069", "site_lbl": "Thr1069", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1069, "start_aa": "Thr", "end_pos": 1069, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1069", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ], "snv": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "Germline mutation passed 1 filters: o-glyco-site-loss (T->A).", "chr_id": "7", "chr_pos": "105687779", "evidence": [ { "id": "rs106679997", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs106679997" } ] } ] }, { "uniprot_canonical_ac": "F1M897-1", "start_pos": "1283", "end_pos": "1283", "site_lbl": "Thr1283", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1283, "start_aa": "Thr", "end_pos": 1283, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1283", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "F1M897-1", "start_pos": "1405", "end_pos": "1405", "site_lbl": "Thr1405", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1405, "start_aa": "Thr", "end_pos": 1405, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1405", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "F1M897-1", "start_pos": "1536", "end_pos": "1536", "site_lbl": "Thr1536", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1536, "start_aa": "Thr", "end_pos": 1536, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1536", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "F1M897-1", "start_pos": "469", "end_pos": "469", "site_lbl": "Thr469", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 469, "start_aa": "Thr", "end_pos": 469, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr469", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "F1M897-1", "start_pos": "713", "end_pos": "713", "site_lbl": "Thr713", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 713, "start_aa": "Thr", "end_pos": 713, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr713", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "F1M897-1", "start_pos": "904", "end_pos": "904", "site_lbl": "Thr904", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 904, "start_aa": "Thr", "end_pos": 904, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr904", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ], "snv": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "Germline mutation passed 1 filters: o-glyco-site-loss (T->A).", "chr_id": "7", "chr_pos": "105718383", "evidence": [ { "id": "rs3321194783", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3321194783" } ] } ] }, { "uniprot_canonical_ac": "F1M897-1", "start_pos": "951", "end_pos": "951", "site_lbl": "Thr951", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 951, "start_aa": "Thr", "end_pos": 951, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr951", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "F1M897-1" }, { "uniprot_canonical_ac": "F1M8E1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1M8E1", "url": "https://www.uniprot.org/uniprotkb/F1M8E1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 364, "chemical_mass": 39535.0, "gene_names": "Ccdc74a;Ccdc74a", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1M8E1-1" }, { "uniprot_canonical_ac": "F1M8M0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1M8M0", "url": "https://www.uniprot.org/uniprotkb/F1M8M0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 970, "chemical_mass": 106694.0, "gene_names": "Rab44;RGD1560150;Rab44", "protein_name": "small monomeric GTPase", "disease": [], "molecular_function": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "F1M8M0", "url": "https://www.uniprot.org/uniprotkb/F1M8M0" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "F1M8M0", "url": "https://www.uniprot.org/uniprotkb/F1M8M0" } ], "pmid": "" }, { "name": "G protein activity", "id": "GO:0003925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003925", "evidence": [ { "database": "UniProtKB", "id": "F1M8M0", "url": "https://www.uniprot.org/uniprotkb/F1M8M0" } ], "pmid": "" } ], "cellular_component": [ { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "F1M8M0", "url": "https://www.uniprot.org/uniprotkb/F1M8M0" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "F1M8M0", "url": "https://www.uniprot.org/uniprotkb/F1M8M0" } ], "pmid": "" }, { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "F1M8M0", "url": "https://www.uniprot.org/uniprotkb/F1M8M0" } ], "pmid": "" } ], "biological_process": [ { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "F1M8M0", "url": "https://www.uniprot.org/uniprotkb/F1M8M0" } ], "pmid": "" }, { "name": "histamine secretion by mast cell", "id": "GO:0002553", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002553", "evidence": [ { "database": "UniProtKB", "id": "F1M8M0", "url": "https://www.uniprot.org/uniprotkb/F1M8M0" } ], "pmid": "" }, { "name": "mast cell degranulation", "id": "GO:0043303", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043303", "evidence": [ { "database": "UniProtKB", "id": "F1M8M0", "url": "https://www.uniprot.org/uniprotkb/F1M8M0" } ], "pmid": "" }, { "name": "histamine secretion mediated by IgE immunoglobulin", "id": "GO:0097279", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097279", "evidence": [ { "database": "UniProtKB", "id": "F1M8M0", "url": "https://www.uniprot.org/uniprotkb/F1M8M0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1M8M0-1" }, { "uniprot_canonical_ac": "F1M8S4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1M8S4", "url": "https://www.uniprot.org/uniprotkb/F1M8S4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1007, "chemical_mass": 112018.0, "gene_names": "Usp35;RGD1565984;Usp35", "protein_name": "ubiquitinyl hydrolase 1", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1M8S4", "url": "https://www.uniprot.org/uniprotkb/F1M8S4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1M8S4", "url": "https://www.uniprot.org/uniprotkb/F1M8S4" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "F1M8S4", "url": "https://www.uniprot.org/uniprotkb/F1M8S4" } ], "pmid": "" }, { "name": "protein deubiquitination", "id": "GO:0016579", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016579", "evidence": [ { "database": "UniProtKB", "id": "F1M8S4", "url": "https://www.uniprot.org/uniprotkb/F1M8S4" } ], "pmid": "" }, { "name": "regulation of protein stability", "id": "GO:0031647", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031647", "evidence": [ { "database": "UniProtKB", "id": "F1M8S4", "url": "https://www.uniprot.org/uniprotkb/F1M8S4" } ], "pmid": "" } ], "molecular_function": [ { "name": "cysteine-type deubiquitinase activity", "id": "GO:0004843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004843", "evidence": [ { "database": "UniProtKB", "id": "F1M8S4", "url": "https://www.uniprot.org/uniprotkb/F1M8S4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1M8S4-1" }, { "uniprot_canonical_ac": "F1M987-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1M987", "url": "https://www.uniprot.org/uniprotkb/F1M987" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1018, "chemical_mass": 111482.0, "gene_names": "Scube1;Scube1", "protein_name": "Signal peptide, CUB and EGF-like domain-containing protein 1", "disease": [], "biological_process": [ { "name": "positive regulation of smoothened signaling pathway", "id": "GO:0045880", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045880", "evidence": [ { "database": "UniProtKB", "id": "F1M987", "url": "https://www.uniprot.org/uniprotkb/F1M987" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "F1M987", "url": "https://www.uniprot.org/uniprotkb/F1M987" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "F1M987", "url": "https://www.uniprot.org/uniprotkb/F1M987" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1M987", "url": "https://www.uniprot.org/uniprotkb/F1M987" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "F1M987", "url": "https://www.uniprot.org/uniprotkb/F1M987" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "F1M987", "url": "https://www.uniprot.org/uniprotkb/F1M987" } ], "pmid": "" }, { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "F1M987", "url": "https://www.uniprot.org/uniprotkb/F1M987" } ], "pmid": "" } ], "molecular_function": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "F1M987", "url": "https://www.uniprot.org/uniprotkb/F1M987" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "F1M987", "url": "https://www.uniprot.org/uniprotkb/F1M987" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1M987-1" }, { "uniprot_canonical_ac": "F1MAD0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1MAD0", "url": "https://www.uniprot.org/uniprotkb/F1MAD0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1615, "chemical_mass": 178980.0, "gene_names": "Lrp5;Lrp5", "protein_name": "Low-density lipoprotein receptor-related protein", "disease": [ { "disease_id": "DOID:0050535", "name": "exudative vitreoretinopathy", "description": "A retinal vascular disease characterized by the prevention of blood vessel formation at the edges of the retina and the hemorrhage of the blood vessels in the retina.", "url": "https://disease-ontology.org/term/DOID:0050535", "evidence": [ { "id": "0050535", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050535" } ], "weight": 0.0 }, { "disease_id": "DOID:0050563", "name": "nonsyndromic deafness", "description": "An auditory system disease that is associated with permanent hearing loss caused by damage to structures in the inner ear and/or the middle ear, which is not associated with other signs and symptoms.", "url": "https://disease-ontology.org/term/DOID:0050563", "evidence": [ { "id": "0050563", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050563" } ], "weight": 0.0 }, { "disease_id": "DOID:0060849", "name": "osteoporosis-pseudoglioma syndrome", "description": "A syndrome characterized by congenital or infancy-onset blindness, very low bone mass, decreased trabecular bone volume, severe juvenile-onset osteoporosis and spontaneous fractures, pseudoglioma, microphthalmia that has_material_basis_in homozygous or compound heterozygous mutation in the LRP5 gene on chromosome 11q13.", "url": "https://disease-ontology.org/term/DOID:0060849", "evidence": [ { "id": "0060849", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060849" } ], "weight": 0.0 }, { "disease_id": "DOID:0060977", "name": "polycystic liver disease 4", "description": "A liver disease characterized by adult-onset of liver cysts arising from the bile duct epithelium that has_material_basis_in heterozygous mutation in the LRP5 gene on chromosome 11q13.", "url": "https://disease-ontology.org/term/DOID:0060977", "evidence": [ { "id": "0060977", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060977" } ], "weight": 0.0 }, { "disease_id": "DOID:0060980", "name": "polycystic liver disease 1", "description": "A polycystic disease characterized by the presence of multiple liver cysts of biliary epithelial origin that has_material_basis_in heterozygous mutation in the PRKCSH gene on chromosome 19p13.", "url": "https://disease-ontology.org/term/DOID:0060980", "evidence": [ { "id": "0060980", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060980" } ], "weight": 0.0 }, { "disease_id": "DOID:0080037", "name": "Worth syndrome", "description": "A hyperostosis that has_material_basis_in a mutation in the LRP5 gene which results_in increased bone density and bony structures located_in palate.", "url": "https://disease-ontology.org/term/DOID:0080037", "evidence": [ { "id": "0080037", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080037" } ], "weight": 0.0 }, { "disease_id": "DOID:0110937", "name": "autosomal dominant osteopetrosis 1", "description": "An osteopetrosis characterized by autosomal dominant inheritance of generalized osteosclerosis that is most pronounced in the cranial vault, absence of increased fractures and has_material_basis_in heterozygous mutation in the LRP5 gene on chromosome 11q13.", "url": "https://disease-ontology.org/term/DOID:0110937", "evidence": [ { "id": "0110937", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110937" } ], "weight": 0.0 }, { "disease_id": "DOID:0111411", "name": "exudative vitreoretinopathy 4", "description": "An exudative vitreoretinopathy that has_material_basis_in homozygous, compound heterozygous, or heterozygous mutation in the LRP5 gene on chromosome 11q13.2.", "url": "https://disease-ontology.org/term/DOID:0111411", "evidence": [ { "id": "0111411", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111411" } ], "weight": 0.0 }, { "disease_id": "DOID:10159", "name": "osteonecrosis", "description": "An ischemic bone disease that results_in necrosis located_in bone.", "url": "https://disease-ontology.org/term/DOID:10159", "evidence": [ { "id": "10159", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10159" } ], "weight": 0.0 }, { "disease_id": "DOID:10629", "name": "microphthalmia", "description": "An eye disease where one or both eyeballs are abnormally small.", "url": "https://disease-ontology.org/term/DOID:10629", "evidence": [ { "id": "10629", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10629" } ], "weight": 0.0 }, { "disease_id": "DOID:11476", "name": "osteoporosis", "description": "A bone resorption disease characterized by decreased density of normally mineralized bone which results_in the thinning of bone tissue and decreased mechanical strength.", "url": "https://disease-ontology.org/term/DOID:11476", "evidence": [ { "id": "11476", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11476" } ], "weight": 0.0 }, { "disease_id": "DOID:12559", "name": "idiopathic juvenile osteoporosis", "description": "An osteoporosis with no known cause that is characterized by pain in the back and extremities, walking difficulties, multiple fractures, and radiological evidence of osteoporosis.", "url": "https://disease-ontology.org/term/DOID:12559", "evidence": [ { "id": "12559", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12559" } ], "weight": 0.0 }, { "disease_id": "DOID:4079", "name": "heart valve disease", "description": "A heart disease involving one or more of the four valves of the heart (the aortic and mitral valves on the left and the pulmonary and tricuspid valves on the right).", "url": "https://disease-ontology.org/term/DOID:4079", "evidence": [ { "id": "4079", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4079" } ], "weight": 0.0 }, { "disease_id": "DOID:898", "name": "autosomal dominant polycystic kidney disease", "description": "A polycystic kidney disease characterized by the presence of multiple cysts located_in the kidney resulting from ciliopathy that disrupts the function of primary cilium, inherited in an autosomal dominant fashion.", "url": "https://disease-ontology.org/term/DOID:898", "evidence": [ { "id": "898", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:898" } ], "weight": 0.0 }, { "disease_id": "DOID:971", "name": "tendinitis", "description": "", "url": "https://disease-ontology.org/term/DOID:971", "evidence": [ { "id": "971", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:971" } ], "weight": 0.0 }, { "disease_id": "DOID:9719", "name": "neovascular inflammatory vitreoretinopathy", "description": "A retinal and vitreous disease characterized by ocular inflammation, vascular dropout, large spots of hyperpigmentation, neovascularization of the peripheral and posterior retina, vitreous hemorrhage, and retinal detachment that has_material_basis_in heterozygous mutation in the CAPN5 gene on chromosome 11q13.5.", "url": "https://disease-ontology.org/term/DOID:9719", "evidence": [ { "id": "9719", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9719" } ], "weight": 0.0 } ], "biological_process": [ { "name": "mammary gland duct morphogenesis", "id": "GO:0060603", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060603", "evidence": [ { "database": "UniProtKB", "id": "F1MAD0", "url": "https://www.uniprot.org/uniprotkb/F1MAD0" } ], "pmid": "" }, { "name": "retina morphogenesis in camera-type eye", "id": "GO:0060042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060042", "evidence": [ { "database": "UniProtKB", "id": "F1MAD0", "url": "https://www.uniprot.org/uniprotkb/F1MAD0" } ], "pmid": "" }, { "name": "establishment of blood-brain barrier", "id": "GO:0060856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060856", "evidence": [ { "database": "UniProtKB", "id": "F1MAD0", "url": "https://www.uniprot.org/uniprotkb/F1MAD0" } ], "pmid": "" }, { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "F1MAD0", "url": "https://www.uniprot.org/uniprotkb/F1MAD0" } ], "pmid": "" }, { "name": "cell-cell signaling", "id": "GO:0007267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007267", "evidence": [ { "database": "UniProtKB", "id": "F1MAD0", "url": "https://www.uniprot.org/uniprotkb/F1MAD0" } ], "pmid": "" }, { "name": "cholesterol metabolic process", "id": "GO:0008203", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008203", "evidence": [ { "database": "UniProtKB", "id": "F1MAD0", "url": "https://www.uniprot.org/uniprotkb/F1MAD0" } ], "pmid": "" }, { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "F1MAD0", "url": "https://www.uniprot.org/uniprotkb/F1MAD0" } ], "pmid": "" }, { "name": "positive regulation of fat cell differentiation", "id": "GO:0045600", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045600", "evidence": [ { "database": "UniProtKB", "id": "F1MAD0", "url": "https://www.uniprot.org/uniprotkb/F1MAD0" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "F1MAD0", "url": "https://www.uniprot.org/uniprotkb/F1MAD0" } ], "pmid": "" }, { "name": "adipose tissue development", "id": "GO:0060612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060612", "evidence": [ { "database": "UniProtKB", "id": "F1MAD0", "url": "https://www.uniprot.org/uniprotkb/F1MAD0" } ], "pmid": "" }, { "name": "regulation of blood pressure", "id": "GO:0008217", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008217", "evidence": [ { "database": "UniProtKB", "id": "F1MAD0", "url": "https://www.uniprot.org/uniprotkb/F1MAD0" } ], "pmid": "" }, { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "F1MAD0", "url": "https://www.uniprot.org/uniprotkb/F1MAD0" } ], "pmid": "" }, { "name": "osteoblast development", "id": "GO:0002076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002076", "evidence": [ { "database": "UniProtKB", "id": "F1MAD0", "url": "https://www.uniprot.org/uniprotkb/F1MAD0" } ], "pmid": "" }, { "name": "cholesterol homeostasis", "id": "GO:0042632", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042632", "evidence": [ { "database": "UniProtKB", "id": "F1MAD0", "url": "https://www.uniprot.org/uniprotkb/F1MAD0" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "F1MAD0", "url": "https://www.uniprot.org/uniprotkb/F1MAD0" } ], "pmid": "" }, { "name": "blood vessel morphogenesis", "id": "GO:0048514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048514", "evidence": [ { "database": "UniProtKB", "id": "F1MAD0", "url": "https://www.uniprot.org/uniprotkb/F1MAD0" } ], "pmid": "" }, { "name": "anterior/posterior pattern specification", "id": "GO:0009952", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009952", "evidence": [ { "database": "UniProtKB", "id": "F1MAD0", "url": "https://www.uniprot.org/uniprotkb/F1MAD0" } ], "pmid": "" }, { "name": "positive regulation of osteoblast proliferation", "id": "GO:0033690", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033690", "evidence": [ { "database": "UniProtKB", "id": "F1MAD0", "url": "https://www.uniprot.org/uniprotkb/F1MAD0" } ], "pmid": "" }, { "name": "bone remodeling", "id": "GO:0046849", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046849", "evidence": [ { "database": "UniProtKB", "id": "F1MAD0", "url": "https://www.uniprot.org/uniprotkb/F1MAD0" } ], "pmid": "" }, { "name": "amino acid transport", "id": "GO:0006865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006865", "evidence": [ { "database": "UniProtKB", "id": "F1MAD0", "url": "https://www.uniprot.org/uniprotkb/F1MAD0" } ], "pmid": "" }, { "name": "Wnt signaling pathway", "id": "GO:0016055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055", "evidence": [ { "database": "UniProtKB", "id": "F1MAD0", "url": "https://www.uniprot.org/uniprotkb/F1MAD0" } ], "pmid": "" }, { "name": "regulation of apoptotic process", "id": "GO:0042981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042981", "evidence": [ { "database": "UniProtKB", "id": "F1MAD0", "url": "https://www.uniprot.org/uniprotkb/F1MAD0" } ], "pmid": "" }, { "name": "retina vasculature development in camera-type eye", "id": "GO:0061298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061298", "evidence": [ { "database": "UniProtKB", "id": "F1MAD0", "url": "https://www.uniprot.org/uniprotkb/F1MAD0" } ], "pmid": "" }, { "name": "gastrulation with mouth forming second", "id": "GO:0001702", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001702", "evidence": [ { "database": "UniProtKB", "id": "F1MAD0", "url": "https://www.uniprot.org/uniprotkb/F1MAD0" } ], "pmid": "" }, { "name": "cell migration involved in gastrulation", "id": "GO:0042074", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042074", "evidence": [ { "database": "UniProtKB", "id": "F1MAD0", "url": "https://www.uniprot.org/uniprotkb/F1MAD0" } ], "pmid": "" }, { "name": "canonical Wnt signaling pathway", "id": "GO:0060070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060070", "evidence": [ { "database": "UniProtKB", "id": "F1MAD0", "url": "https://www.uniprot.org/uniprotkb/F1MAD0" } ], "pmid": "" }, { "name": "bone development", "id": "GO:0060348", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060348", "evidence": [ { "database": "UniProtKB", "id": "F1MAD0", "url": "https://www.uniprot.org/uniprotkb/F1MAD0" } ], "pmid": "" }, { "name": "bone morphogenesis", "id": "GO:0060349", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060349", "evidence": [ { "database": "UniProtKB", "id": "F1MAD0", "url": "https://www.uniprot.org/uniprotkb/F1MAD0" } ], "pmid": "" }, { "name": "positive regulation of osteoblast differentiation", "id": "GO:0045669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045669", "evidence": [ { "database": "UniProtKB", "id": "F1MAD0", "url": "https://www.uniprot.org/uniprotkb/F1MAD0" } ], "pmid": "" }, { "name": "regulation of insulin secretion involved in cellular response to glucose stimulus", "id": "GO:0061178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061178", "evidence": [ { "database": "UniProtKB", "id": "F1MAD0", "url": "https://www.uniprot.org/uniprotkb/F1MAD0" } ], "pmid": "" }, { "name": "vasculature development", "id": "GO:0001944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001944", "evidence": [ { "database": "UniProtKB", "id": "F1MAD0", "url": "https://www.uniprot.org/uniprotkb/F1MAD0" } ], "pmid": "" }, { "name": "embryonic digit morphogenesis", "id": "GO:0042733", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042733", "evidence": [ { "database": "UniProtKB", "id": "F1MAD0", "url": "https://www.uniprot.org/uniprotkb/F1MAD0" } ], "pmid": "" }, { "name": "response to peptide hormone", "id": "GO:0043434", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043434", "evidence": [ { "database": "UniProtKB", "id": "F1MAD0", "url": "https://www.uniprot.org/uniprotkb/F1MAD0" } ], "pmid": "" }, { "name": "negative regulation of osteoblast differentiation", "id": "GO:0045668", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045668", "evidence": [ { "database": "UniProtKB", "id": "F1MAD0", "url": "https://www.uniprot.org/uniprotkb/F1MAD0" } ], "pmid": "" }, { "name": "somatic stem cell population maintenance", "id": "GO:0035019", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035019", "evidence": [ { "database": "UniProtKB", "id": "F1MAD0", "url": "https://www.uniprot.org/uniprotkb/F1MAD0" } ], "pmid": "" }, { "name": "retina vasculature morphogenesis in camera-type eye", "id": "GO:0061299", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061299", "evidence": [ { "database": "UniProtKB", "id": "F1MAD0", "url": "https://www.uniprot.org/uniprotkb/F1MAD0" } ], "pmid": "" }, { "name": "limb morphogenesis", "id": "GO:0035108", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035108", "evidence": [ { "database": "UniProtKB", "id": "F1MAD0", "url": "https://www.uniprot.org/uniprotkb/F1MAD0" } ], "pmid": "" }, { "name": "apoptotic process involved in blood vessel morphogenesis", "id": "GO:1902262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902262", "evidence": [ { "database": "UniProtKB", "id": "F1MAD0", "url": "https://www.uniprot.org/uniprotkb/F1MAD0" } ], "pmid": "" }, { "name": "extracellular matrix-cell signaling", "id": "GO:0035426", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035426", "evidence": [ { "database": "UniProtKB", "id": "F1MAD0", "url": "https://www.uniprot.org/uniprotkb/F1MAD0" } ], "pmid": "" }, { "name": "positive regulation of mitotic nuclear division", "id": "GO:0045840", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045840", "evidence": [ { "database": "UniProtKB", "id": "F1MAD0", "url": "https://www.uniprot.org/uniprotkb/F1MAD0" } ], "pmid": "" }, { "name": "bone marrow development", "id": "GO:0048539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048539", "evidence": [ { "database": "UniProtKB", "id": "F1MAD0", "url": "https://www.uniprot.org/uniprotkb/F1MAD0" } ], "pmid": "" }, { "name": "gene expression", "id": "GO:0010467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010467", "evidence": [ { "database": "UniProtKB", "id": "F1MAD0", "url": "https://www.uniprot.org/uniprotkb/F1MAD0" } ], "pmid": "" }, { "name": "glucose catabolic process", "id": "GO:0006007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006007", "evidence": [ { "database": "UniProtKB", "id": "F1MAD0", "url": "https://www.uniprot.org/uniprotkb/F1MAD0" } ], "pmid": "" }, { "name": "positive regulation of mesenchymal cell proliferation", "id": "GO:0002053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002053", "evidence": [ { "database": "UniProtKB", "id": "F1MAD0", "url": "https://www.uniprot.org/uniprotkb/F1MAD0" } ], "pmid": "" }, { "name": "branching involved in mammary gland duct morphogenesis", "id": "GO:0060444", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060444", "evidence": [ { "database": "UniProtKB", "id": "F1MAD0", "url": "https://www.uniprot.org/uniprotkb/F1MAD0" } ], "pmid": "" }, { "name": "anatomical structure regression", "id": "GO:0060033", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060033", "evidence": [ { "database": "UniProtKB", "id": "F1MAD0", "url": "https://www.uniprot.org/uniprotkb/F1MAD0" } ], "pmid": "" }, { "name": "retinal blood vessel morphogenesis", "id": "GO:0061304", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061304", "evidence": [ { "database": "UniProtKB", "id": "F1MAD0", "url": "https://www.uniprot.org/uniprotkb/F1MAD0" } ], "pmid": "" }, { "name": "establishment of blood-retinal barrier", "id": "GO:1990963", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990963", "evidence": [ { "database": "UniProtKB", "id": "F1MAD0", "url": "https://www.uniprot.org/uniprotkb/F1MAD0" } ], "pmid": "" }, { "name": "Norrin signaling pathway", "id": "GO:0110135", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0110135", "evidence": [ { "database": "UniProtKB", "id": "F1MAD0", "url": "https://www.uniprot.org/uniprotkb/F1MAD0" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1MAD0", "url": "https://www.uniprot.org/uniprotkb/F1MAD0" } ], "pmid": "" }, { "name": "receptor complex", "id": "GO:0043235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043235", "evidence": [ { "database": "UniProtKB", "id": "F1MAD0", "url": "https://www.uniprot.org/uniprotkb/F1MAD0" } ], "pmid": "" } ], "molecular_function": [ { "name": "coreceptor activity", "id": "GO:0015026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015026", "evidence": [ { "database": "UniProtKB", "id": "F1MAD0", "url": "https://www.uniprot.org/uniprotkb/F1MAD0" } ], "pmid": "" }, { "name": "Wnt-protein binding", "id": "GO:0017147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017147", "evidence": [ { "database": "UniProtKB", "id": "F1MAD0", "url": "https://www.uniprot.org/uniprotkb/F1MAD0" } ], "pmid": "" }, { "name": "Wnt receptor activity", "id": "GO:0042813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042813", "evidence": [ { "database": "UniProtKB", "id": "F1MAD0", "url": "https://www.uniprot.org/uniprotkb/F1MAD0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "F1MAD0-1", "start_pos": "1578", "end_pos": "1578", "site_lbl": "Thr1578", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1578, "start_aa": "Thr", "end_pos": 1578, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1578", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "F1MAD0-1" }, { "uniprot_canonical_ac": "F1MAG8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1MAG8", "url": "https://www.uniprot.org/uniprotkb/F1MAG8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 777, "chemical_mass": 89532.0, "gene_names": "Sema3d;Sema3d", "protein_name": "", "disease": [ { "disease_id": "DOID:0080815", "name": "childhood-onset asthma", "description": "A chronic asthma that is characterized by first presentation in early childhood.", "url": "https://disease-ontology.org/term/DOID:0080815", "evidence": [ { "id": "0080815", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080815" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "F1MAG8", "url": "https://www.uniprot.org/uniprotkb/F1MAG8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1MAG8", "url": "https://www.uniprot.org/uniprotkb/F1MAG8" } ], "pmid": "" } ], "molecular_function": [ { "name": "semaphorin receptor binding", "id": "GO:0030215", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030215", "evidence": [ { "database": "UniProtKB", "id": "F1MAG8", "url": "https://www.uniprot.org/uniprotkb/F1MAG8" } ], "pmid": "" }, { "name": "neuropilin binding", "id": "GO:0038191", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038191", "evidence": [ { "database": "UniProtKB", "id": "F1MAG8", "url": "https://www.uniprot.org/uniprotkb/F1MAG8" } ], "pmid": "" }, { "name": "chemorepellent activity", "id": "GO:0045499", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045499", "evidence": [ { "database": "UniProtKB", "id": "F1MAG8", "url": "https://www.uniprot.org/uniprotkb/F1MAG8" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of cell migration", "id": "GO:0030335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030335", "evidence": [ { "database": "UniProtKB", "id": "F1MAG8", "url": "https://www.uniprot.org/uniprotkb/F1MAG8" } ], "pmid": "" }, { "name": "semaphorin-plexin signaling pathway", "id": "GO:0071526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071526", "evidence": [ { "database": "UniProtKB", "id": "F1MAG8", "url": "https://www.uniprot.org/uniprotkb/F1MAG8" } ], "pmid": "" }, { "name": "neural crest cell migration", "id": "GO:0001755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001755", "evidence": [ { "database": "UniProtKB", "id": "F1MAG8", "url": "https://www.uniprot.org/uniprotkb/F1MAG8" } ], "pmid": "" }, { "name": "negative chemotaxis", "id": "GO:0050919", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050919", "evidence": [ { "database": "UniProtKB", "id": "F1MAG8", "url": "https://www.uniprot.org/uniprotkb/F1MAG8" } ], "pmid": "" }, { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "F1MAG8", "url": "https://www.uniprot.org/uniprotkb/F1MAG8" } ], "pmid": "" }, { "name": "regulation of plasma membrane bounded cell projection organization", "id": "GO:0120035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120035", "evidence": [ { "database": "UniProtKB", "id": "F1MAG8", "url": "https://www.uniprot.org/uniprotkb/F1MAG8" } ], "pmid": "" }, { "name": "negative regulation of developmental process", "id": "GO:0051093", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051093", "evidence": [ { "database": "UniProtKB", "id": "F1MAG8", "url": "https://www.uniprot.org/uniprotkb/F1MAG8" } ], "pmid": "" }, { "name": "regulation of multicellular organismal development", "id": "GO:2000026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000026", "evidence": [ { "database": "UniProtKB", "id": "F1MAG8", "url": "https://www.uniprot.org/uniprotkb/F1MAG8" } ], "pmid": "" }, { "name": "regulation of anatomical structure morphogenesis", "id": "GO:0022603", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022603", "evidence": [ { "database": "UniProtKB", "id": "F1MAG8", "url": "https://www.uniprot.org/uniprotkb/F1MAG8" } ], "pmid": "" }, { "name": "negative regulation of multicellular organismal process", "id": "GO:0051241", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051241", "evidence": [ { "database": "UniProtKB", "id": "F1MAG8", "url": "https://www.uniprot.org/uniprotkb/F1MAG8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1MAG8-1" }, { "uniprot_canonical_ac": "F1MAJ8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1MAJ8", "url": "https://www.uniprot.org/uniprotkb/F1MAJ8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 568, "chemical_mass": 63194.0, "gene_names": "Zfp91;Zfp91", "protein_name": "E3 ubiquitin-protein ligase ZFP91", "disease": [ { "disease_id": "DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ], "weight": 0.0 }, { "disease_id": "DOID:9119", "name": "acute myeloid leukemia", "description": "A myeloid leukemia that is characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal blood cells.", "url": "https://disease-ontology.org/term/DOID:9119", "evidence": [ { "id": "9119", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9119" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1MAJ8", "url": "https://www.uniprot.org/uniprotkb/F1MAJ8" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1MAJ8", "url": "https://www.uniprot.org/uniprotkb/F1MAJ8" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "F1MAJ8", "url": "https://www.uniprot.org/uniprotkb/F1MAJ8" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "F1MAJ8", "url": "https://www.uniprot.org/uniprotkb/F1MAJ8" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "F1MAJ8", "url": "https://www.uniprot.org/uniprotkb/F1MAJ8" } ], "pmid": "" }, { "name": "protein K63-linked ubiquitination", "id": "GO:0070534", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070534", "evidence": [ { "database": "UniProtKB", "id": "F1MAJ8", "url": "https://www.uniprot.org/uniprotkb/F1MAJ8" } ], "pmid": "" }, { "name": "activation of NF-kappaB-inducing kinase activity", "id": "GO:0007250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007250", "evidence": [ { "database": "UniProtKB", "id": "F1MAJ8", "url": "https://www.uniprot.org/uniprotkb/F1MAJ8" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1MAJ8", "url": "https://www.uniprot.org/uniprotkb/F1MAJ8" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "F1MAJ8", "url": "https://www.uniprot.org/uniprotkb/F1MAJ8" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "F1MAJ8", "url": "https://www.uniprot.org/uniprotkb/F1MAJ8" } ], "pmid": "" }, { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "F1MAJ8", "url": "https://www.uniprot.org/uniprotkb/F1MAJ8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1MAJ8-1" }, { "uniprot_canonical_ac": "F1MAK1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1MAK1", "url": "https://www.uniprot.org/uniprotkb/F1MAK1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1048, "chemical_mass": 113087.0, "gene_names": "Fnbp4", "protein_name": "Formin-binding protein 4", "disease": [], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1MAK1", "url": "https://www.uniprot.org/uniprotkb/F1MAK1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "F1MAK1-1", "start_pos": "202", "end_pos": "202", "site_lbl": "Thr202", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 202, "start_aa": "Thr", "end_pos": 202, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr202", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "F1MAK1-1", "start_pos": "53", "end_pos": "53", "site_lbl": "Thr53", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 53, "start_aa": "Thr", "end_pos": 53, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr53", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "F1MAK1-1", "start_pos": "73", "end_pos": "73", "site_lbl": "Thr73", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 73, "start_aa": "Thr", "end_pos": 73, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr73", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "F1MAK1-1", "start_pos": "943", "end_pos": "943", "site_lbl": "Thr943", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 943, "start_aa": "Thr", "end_pos": 943, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr943", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "F1MAK1-1" }, { "uniprot_canonical_ac": "F1MAK4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1MAK4", "url": "https://www.uniprot.org/uniprotkb/F1MAK4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 319, "chemical_mass": 36687.0, "gene_names": "Gpr55;Gpr55", "protein_name": "", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1MAK4", "url": "https://www.uniprot.org/uniprotkb/F1MAK4" } ], "pmid": "" } ], "biological_process": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "F1MAK4", "url": "https://www.uniprot.org/uniprotkb/F1MAK4" } ], "pmid": "" }, { "name": "positive regulation of ERK1 and ERK2 cascade", "id": "GO:0070374", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070374", "evidence": [ { "database": "UniProtKB", "id": "F1MAK4", "url": "https://www.uniprot.org/uniprotkb/F1MAK4" } ], "pmid": "" }, { "name": "phospholipase C-activating G protein-coupled receptor signaling pathway", "id": "GO:0007200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007200", "evidence": [ { "database": "UniProtKB", "id": "F1MAK4", "url": "https://www.uniprot.org/uniprotkb/F1MAK4" } ], "pmid": "" }, { "name": "bone resorption", "id": "GO:0045453", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045453", "evidence": [ { "database": "UniProtKB", "id": "F1MAK4", "url": "https://www.uniprot.org/uniprotkb/F1MAK4" } ], "pmid": "" }, { "name": "positive regulation of Rho protein signal transduction", "id": "GO:0035025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035025", "evidence": [ { "database": "UniProtKB", "id": "F1MAK4", "url": "https://www.uniprot.org/uniprotkb/F1MAK4" } ], "pmid": "" }, { "name": "negative regulation of osteoclast differentiation", "id": "GO:0045671", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045671", "evidence": [ { "database": "UniProtKB", "id": "F1MAK4", "url": "https://www.uniprot.org/uniprotkb/F1MAK4" } ], "pmid": "" } ], "molecular_function": [ { "name": "cannabinoid receptor activity", "id": "GO:0004949", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004949", "evidence": [ { "database": "UniProtKB", "id": "F1MAK4", "url": "https://www.uniprot.org/uniprotkb/F1MAK4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1MAK4-1" }, { "uniprot_canonical_ac": "F1MAL8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1MAL8", "url": "https://www.uniprot.org/uniprotkb/F1MAL8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1286, "chemical_mass": 140958.0, "gene_names": "Hmgxb3;Hmgxb3", "protein_name": "", "disease": [], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "F1MAL8", "url": "https://www.uniprot.org/uniprotkb/F1MAL8" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1MAL8", "url": "https://www.uniprot.org/uniprotkb/F1MAL8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1MAL8-1" }, { "uniprot_canonical_ac": "F1MAM5-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1MAM5", "url": "https://www.uniprot.org/uniprotkb/F1MAM5" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 727, "chemical_mass": 82933.0, "gene_names": "Zfp719;LOC100361791;LOC102556967;Zfp719", "protein_name": "", "disease": [], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "F1MAM5", "url": "https://www.uniprot.org/uniprotkb/F1MAM5" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1MAM5", "url": "https://www.uniprot.org/uniprotkb/F1MAM5" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "F1MAM5", "url": "https://www.uniprot.org/uniprotkb/F1MAM5" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "F1MAM5", "url": "https://www.uniprot.org/uniprotkb/F1MAM5" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "F1MAM5", "url": "https://www.uniprot.org/uniprotkb/F1MAM5" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1MAM5", "url": "https://www.uniprot.org/uniprotkb/F1MAM5" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1MAM5", "url": "https://www.uniprot.org/uniprotkb/F1MAM5" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "F1MAM5", "url": "https://www.uniprot.org/uniprotkb/F1MAM5" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "F1MAM5", "url": "https://www.uniprot.org/uniprotkb/F1MAM5" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "F1MAM5", "url": "https://www.uniprot.org/uniprotkb/F1MAM5" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "F1MAM5", "url": "https://www.uniprot.org/uniprotkb/F1MAM5" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "F1MAM5", "url": "https://www.uniprot.org/uniprotkb/F1MAM5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F1MAM5-1" }, { "uniprot_canonical_ac": "F2Z3R5-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F2Z3R5", "url": "https://www.uniprot.org/uniprotkb/F2Z3R5" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 818, "chemical_mass": 90503.0, "gene_names": "Pcdhb1;Pcdhb1", "protein_name": "Protocadherin beta-1", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F2Z3R5", "url": "https://www.uniprot.org/uniprotkb/F2Z3R5" } ], "pmid": "" } ], "biological_process": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "F2Z3R5", "url": "https://www.uniprot.org/uniprotkb/F2Z3R5" } ], "pmid": "" }, { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "F2Z3R5", "url": "https://www.uniprot.org/uniprotkb/F2Z3R5" } ], "pmid": "" } ], "molecular_function": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "F2Z3R5", "url": "https://www.uniprot.org/uniprotkb/F2Z3R5" } ], "pmid": "" }, { "name": "cell adhesion molecule binding", "id": "GO:0050839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050839", "evidence": [ { "database": "UniProtKB", "id": "F2Z3R5", "url": "https://www.uniprot.org/uniprotkb/F2Z3R5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F2Z3R5-1" }, { "uniprot_canonical_ac": "F7EV11-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F7EV11", "url": "https://www.uniprot.org/uniprotkb/F7EV11" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 511, "chemical_mass": 55897.0, "gene_names": "Spag8", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F7EV11", "url": "https://www.uniprot.org/uniprotkb/F7EV11" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F7EV11", "url": "https://www.uniprot.org/uniprotkb/F7EV11" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "F7EV11", "url": "https://www.uniprot.org/uniprotkb/F7EV11" } ], "pmid": "" }, { "name": "sperm flagellum", "id": "GO:0036126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036126", "evidence": [ { "database": "UniProtKB", "id": "F7EV11", "url": "https://www.uniprot.org/uniprotkb/F7EV11" } ], "pmid": "" }, { "name": "axonemal microtubule", "id": "GO:0005879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005879", "evidence": [ { "database": "UniProtKB", "id": "F7EV11", "url": "https://www.uniprot.org/uniprotkb/F7EV11" } ], "pmid": "" }, { "name": "axonemal A tubule inner sheath", "id": "GO:0160111", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160111", "evidence": [ { "database": "UniProtKB", "id": "F7EV11", "url": "https://www.uniprot.org/uniprotkb/F7EV11" } ], "pmid": "" } ], "molecular_function": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "F7EV11", "url": "https://www.uniprot.org/uniprotkb/F7EV11" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "F7EV11", "url": "https://www.uniprot.org/uniprotkb/F7EV11" } ], "pmid": "" }, { "name": "flagellated sperm motility", "id": "GO:0030317", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030317", "evidence": [ { "database": "UniProtKB", "id": "F7EV11", "url": "https://www.uniprot.org/uniprotkb/F7EV11" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "F7EV11-1", "start_pos": "147", "end_pos": "147", "site_lbl": "Thr147", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 147, "start_aa": "Thr", "end_pos": 147, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr147", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "F7EV11-1" }, { "uniprot_canonical_ac": "F7EXD0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F7EXD0", "url": "https://www.uniprot.org/uniprotkb/F7EXD0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 559, "chemical_mass": 64843.0, "gene_names": "Det1", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F7EXD0", "url": "https://www.uniprot.org/uniprotkb/F7EXD0" } ], "pmid": "" }, { "name": "cullin-RING ubiquitin ligase complex", "id": "GO:0031461", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031461", "evidence": [ { "database": "UniProtKB", "id": "F7EXD0", "url": "https://www.uniprot.org/uniprotkb/F7EXD0" } ], "pmid": "" }, { "name": "Cul4A-RING E3 ubiquitin ligase complex", "id": "GO:0031464", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031464", "evidence": [ { "database": "UniProtKB", "id": "F7EXD0", "url": "https://www.uniprot.org/uniprotkb/F7EXD0" } ], "pmid": "" }, { "name": "Cul4-RING E3 ubiquitin ligase complex", "id": "GO:0080008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0080008", "evidence": [ { "database": "UniProtKB", "id": "F7EXD0", "url": "https://www.uniprot.org/uniprotkb/F7EXD0" } ], "pmid": "" } ], "molecular_function": [ { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "F7EXD0", "url": "https://www.uniprot.org/uniprotkb/F7EXD0" } ], "pmid": "" }, { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "F7EXD0", "url": "https://www.uniprot.org/uniprotkb/F7EXD0" } ], "pmid": "" }, { "name": "protein-containing complex binding", "id": "GO:0044877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044877", "evidence": [ { "database": "UniProtKB", "id": "F7EXD0", "url": "https://www.uniprot.org/uniprotkb/F7EXD0" } ], "pmid": "" } ], "biological_process": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "F7EXD0", "url": "https://www.uniprot.org/uniprotkb/F7EXD0" } ], "pmid": "" }, { "name": "positive regulation of proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0032436", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032436", "evidence": [ { "database": "UniProtKB", "id": "F7EXD0", "url": "https://www.uniprot.org/uniprotkb/F7EXD0" } ], "pmid": "" }, { "name": "protein-containing complex assembly", "id": "GO:0065003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0065003", "evidence": [ { "database": "UniProtKB", "id": "F7EXD0", "url": "https://www.uniprot.org/uniprotkb/F7EXD0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F7EXD0-1" }, { "uniprot_canonical_ac": "F7FHF3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F7FHF3", "url": "https://www.uniprot.org/uniprotkb/F7FHF3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 554, "chemical_mass": 62291.0, "gene_names": "Serpinf2", "protein_name": "", "disease": [ { "disease_id": "DOID:0050831", "name": "familial encephalopathy with neuroserpin inclusion bodies", "description": "A neurodegenerative disease that is characterized by intraneuronal inclusions of mutant neuroserpin resulting in progressive encephalopathy, dementia and seizures and has_material_basis_in a mutation in the SERPINI1 gene inherited in an in autosomal dominant pattern.", "url": "https://disease-ontology.org/term/DOID:0050831", "evidence": [ { "id": "0050831", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050831" } ], "weight": 0.0 }, { "disease_id": "DOID:0060601", "name": "alpha-2-plasmin inhibitor deficiency", "description": "A hemorrhagic disease that has_material_basis_in mutation in the PLI gene. It is characterized by a hemorrhagic tendency presenting from childhood with prolonged bleeding and ecchymoses following minor trauma and spontaneous bleeding episodes.", "url": "https://disease-ontology.org/term/DOID:0060601", "evidence": [ { "id": "0060601", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060601" } ], "weight": 0.0 }, { "disease_id": "DOID:0080600", "name": "COVID-19", "description": "A Coronavirus infectious disease that is characterized by fever, cough and shortness of breath and that has_material_basis_in Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a subtype of Betacoronavirus pandemicum.", "url": "https://disease-ontology.org/term/DOID:0080600", "evidence": [ { "id": "0080600", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080600" } ], "weight": 0.0 }, { "disease_id": "DOID:0080998", "name": "acute necrotizing pancreatitis", "description": "An acute pancreatitis that is characterized by one or more areas of necrosis in the pancreas with varying degree of involvement of the surrounding tissues or organ systems.", "url": "https://disease-ontology.org/term/DOID:0080998", "evidence": [ { "id": "0080998", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080998" } ], "weight": 0.0 }, { "disease_id": "DOID:10591", "name": "pre-eclampsia", "description": "A hypertension occurring during pregnancy characterized by large amounts of protein in the urine (proteinuria) and edema, usually by the last trimester of pregnancy.", "url": "https://disease-ontology.org/term/DOID:10591", "evidence": [ { "id": "10591", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10591" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:1168", "name": "familial hyperlipidemia", "description": "A lipid metabolism disease that is characterized by elevated levels of lipids in the blood.", "url": "https://disease-ontology.org/term/DOID:1168", "evidence": [ { "id": "1168", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1168" } ], "weight": 0.0 }, { "disease_id": "DOID:3393", "name": "coronary artery disease", "description": "An artery disease that is characterized by plaque building up along the inner walls of the arteries of the heart resulting in a narrowing of the arteries and a reduced blood supply to the cardiac muscles.", "url": "https://disease-ontology.org/term/DOID:3393", "evidence": [ { "id": "3393", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3393" } ], "weight": 0.0 }, { "disease_id": "DOID:418", "name": "systemic scleroderma", "description": "A scleroderma that is characterized by fibrosis (or hardening) of the skin and major organs, as well as vascular alterations, and autoantibodies.", "url": "https://disease-ontology.org/term/DOID:418", "evidence": [ { "id": "418", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:418" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "protease binding", "id": "GO:0002020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002020", "evidence": [ { "database": "UniProtKB", "id": "F7FHF3", "url": "https://www.uniprot.org/uniprotkb/F7FHF3" } ], "pmid": "" }, { "name": "serine-type endopeptidase inhibitor activity", "id": "GO:0004867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004867", "evidence": [ { "database": "UniProtKB", "id": "F7FHF3", "url": "https://www.uniprot.org/uniprotkb/F7FHF3" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "F7FHF3", "url": "https://www.uniprot.org/uniprotkb/F7FHF3" } ], "pmid": "" }, { "name": "endopeptidase inhibitor activity", "id": "GO:0004866", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004866", "evidence": [ { "database": "UniProtKB", "id": "F7FHF3", "url": "https://www.uniprot.org/uniprotkb/F7FHF3" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "F7FHF3", "url": "https://www.uniprot.org/uniprotkb/F7FHF3" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "F7FHF3", "url": "https://www.uniprot.org/uniprotkb/F7FHF3" } ], "pmid": "" }, { "name": "fibrinogen complex", "id": "GO:0005577", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005577", "evidence": [ { "database": "UniProtKB", "id": "F7FHF3", "url": "https://www.uniprot.org/uniprotkb/F7FHF3" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "F7FHF3", "url": "https://www.uniprot.org/uniprotkb/F7FHF3" } ], "pmid": "" }, { "name": "positive regulation of JNK cascade", "id": "GO:0046330", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046330", "evidence": [ { "database": "UniProtKB", "id": "F7FHF3", "url": "https://www.uniprot.org/uniprotkb/F7FHF3" } ], "pmid": "" }, { "name": "positive regulation of ERK1 and ERK2 cascade", "id": "GO:0070374", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070374", "evidence": [ { "database": "UniProtKB", "id": "F7FHF3", "url": "https://www.uniprot.org/uniprotkb/F7FHF3" } ], "pmid": "" }, { "name": "maintenance of blood vessel diameter homeostasis by renin-angiotensin", "id": "GO:0002034", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002034", "evidence": [ { "database": "UniProtKB", "id": "F7FHF3", "url": "https://www.uniprot.org/uniprotkb/F7FHF3" } ], "pmid": "" }, { "name": "negative regulation of plasminogen activation", "id": "GO:0010757", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010757", "evidence": [ { "database": "UniProtKB", "id": "F7FHF3", "url": "https://www.uniprot.org/uniprotkb/F7FHF3" } ], "pmid": "" }, { "name": "collagen fibril organization", "id": "GO:0030199", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030199", "evidence": [ { "database": "UniProtKB", "id": "F7FHF3", "url": "https://www.uniprot.org/uniprotkb/F7FHF3" } ], "pmid": "" }, { "name": "positive regulation of collagen biosynthetic process", "id": "GO:0032967", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032967", "evidence": [ { "database": "UniProtKB", "id": "F7FHF3", "url": "https://www.uniprot.org/uniprotkb/F7FHF3" } ], "pmid": "" }, { "name": "positive regulation of cell differentiation", "id": "GO:0045597", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045597", "evidence": [ { "database": "UniProtKB", "id": "F7FHF3", "url": "https://www.uniprot.org/uniprotkb/F7FHF3" } ], "pmid": "" }, { "name": "blood vessel morphogenesis", "id": "GO:0048514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048514", "evidence": [ { "database": "UniProtKB", "id": "F7FHF3", "url": "https://www.uniprot.org/uniprotkb/F7FHF3" } ], "pmid": "" }, { "name": "positive regulation of smooth muscle cell proliferation", "id": "GO:0048661", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048661", "evidence": [ { "database": "UniProtKB", "id": "F7FHF3", "url": "https://www.uniprot.org/uniprotkb/F7FHF3" } ], "pmid": "" }, { "name": "positive regulation of stress fiber assembly", "id": "GO:0051496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051496", "evidence": [ { "database": "UniProtKB", "id": "F7FHF3", "url": "https://www.uniprot.org/uniprotkb/F7FHF3" } ], "pmid": "" }, { "name": "negative regulation of fibrinolysis", "id": "GO:0051918", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051918", "evidence": [ { "database": "UniProtKB", "id": "F7FHF3", "url": "https://www.uniprot.org/uniprotkb/F7FHF3" } ], "pmid": "" }, { "name": "positive regulation of transforming growth factor beta production", "id": "GO:0071636", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071636", "evidence": [ { "database": "UniProtKB", "id": "F7FHF3", "url": "https://www.uniprot.org/uniprotkb/F7FHF3" } ], "pmid": "" }, { "name": "positive regulation of coagulation", "id": "GO:0050820", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050820", "evidence": [ { "database": "UniProtKB", "id": "F7FHF3", "url": "https://www.uniprot.org/uniprotkb/F7FHF3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F7FHF3-1" }, { "uniprot_canonical_ac": "F7FKF2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F7FKF2", "url": "https://www.uniprot.org/uniprotkb/F7FKF2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 705, "chemical_mass": 78238.0, "gene_names": "AABR07025089.1", "protein_name": "Nucleophosmin", "disease": [], "biological_process": [ { "name": "regulation of centrosome duplication", "id": "GO:0010824", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010824", "evidence": [ { "database": "UniProtKB", "id": "F7FKF2", "url": "https://www.uniprot.org/uniprotkb/F7FKF2" } ], "pmid": "" }, { "name": "ribosomal large subunit export from nucleus", "id": "GO:0000055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000055", "evidence": [ { "database": "UniProtKB", "id": "F7FKF2", "url": "https://www.uniprot.org/uniprotkb/F7FKF2" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "F7FKF2", "url": "https://www.uniprot.org/uniprotkb/F7FKF2" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "F7FKF2", "url": "https://www.uniprot.org/uniprotkb/F7FKF2" } ], "pmid": "" }, { "name": "ribosomal large subunit biogenesis", "id": "GO:0042273", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042273", "evidence": [ { "database": "UniProtKB", "id": "F7FKF2", "url": "https://www.uniprot.org/uniprotkb/F7FKF2" } ], "pmid": "" }, { "name": "ribosomal small subunit export from nucleus", "id": "GO:0000056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000056", "evidence": [ { "database": "UniProtKB", "id": "F7FKF2", "url": "https://www.uniprot.org/uniprotkb/F7FKF2" } ], "pmid": "" }, { "name": "ribosomal small subunit biogenesis", "id": "GO:0042274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042274", "evidence": [ { "database": "UniProtKB", "id": "F7FKF2", "url": "https://www.uniprot.org/uniprotkb/F7FKF2" } ], "pmid": "" } ], "molecular_function": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "F7FKF2", "url": "https://www.uniprot.org/uniprotkb/F7FKF2" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "F7FKF2", "url": "https://www.uniprot.org/uniprotkb/F7FKF2" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "F7FKF2", "url": "https://www.uniprot.org/uniprotkb/F7FKF2" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F7FKF2", "url": "https://www.uniprot.org/uniprotkb/F7FKF2" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "F7FKF2", "url": "https://www.uniprot.org/uniprotkb/F7FKF2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F7FKF2", "url": "https://www.uniprot.org/uniprotkb/F7FKF2" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "F7FKF2", "url": "https://www.uniprot.org/uniprotkb/F7FKF2" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "F7FKF2", "url": "https://www.uniprot.org/uniprotkb/F7FKF2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "F7FKF2-1", "start_pos": "177", "end_pos": "177", "site_lbl": "Thr177", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 177, "start_aa": "Thr", "end_pos": 177, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr177", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "F7FKF2-1", "start_pos": "363", "end_pos": "363", "site_lbl": "Thr363", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 363, "start_aa": "Thr", "end_pos": 363, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr363", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "F7FKF2-1" }, { "uniprot_canonical_ac": "F7FM87-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F7FM87", "url": "https://www.uniprot.org/uniprotkb/F7FM87" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 332, "chemical_mass": 37084.0, "gene_names": "Erich1;Erich1;RGD1559872", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F7FM87-1" }, { "uniprot_canonical_ac": "F7FMS0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F7FMS0", "url": "https://www.uniprot.org/uniprotkb/F7FMS0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 739, "chemical_mass": 83145.0, "gene_names": "Mst1", "protein_name": "Hepatocyte growth factor-like protein", "disease": [ { "disease_id": "DOID:0050589", "name": "inflammatory bowel disease", "description": "An intestinal disease characterized by inflammation located in all parts of digestive tract.", "url": "https://disease-ontology.org/term/DOID:0050589", "evidence": [ { "id": "0050589", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050589" } ], "weight": 0.0 }, { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 } ], "biological_process": [ { "name": "regulation of receptor signaling pathway via JAK-STAT", "id": "GO:0046425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046425", "evidence": [ { "database": "UniProtKB", "id": "F7FMS0", "url": "https://www.uniprot.org/uniprotkb/F7FMS0" } ], "pmid": "" }, { "name": "negative regulation of epithelial cell apoptotic process", "id": "GO:1904036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904036", "evidence": [ { "database": "UniProtKB", "id": "F7FMS0", "url": "https://www.uniprot.org/uniprotkb/F7FMS0" } ], "pmid": "" }, { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "F7FMS0", "url": "https://www.uniprot.org/uniprotkb/F7FMS0" } ], "pmid": "" }, { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "F7FMS0", "url": "https://www.uniprot.org/uniprotkb/F7FMS0" } ], "pmid": "" }, { "name": "positive regulation of gene expression", "id": "GO:0010628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010628", "evidence": [ { "database": "UniProtKB", "id": "F7FMS0", "url": "https://www.uniprot.org/uniprotkb/F7FMS0" } ], "pmid": "" }, { "name": "positive regulation of apoptotic process", "id": "GO:0043065", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043065", "evidence": [ { "database": "UniProtKB", "id": "F7FMS0", "url": "https://www.uniprot.org/uniprotkb/F7FMS0" } ], "pmid": "" }, { "name": "flagellated sperm motility", "id": "GO:0030317", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030317", "evidence": [ { "database": "UniProtKB", "id": "F7FMS0", "url": "https://www.uniprot.org/uniprotkb/F7FMS0" } ], "pmid": "" }, { "name": "cellular response to hypoxia", "id": "GO:0071456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071456", "evidence": [ { "database": "UniProtKB", "id": "F7FMS0", "url": "https://www.uniprot.org/uniprotkb/F7FMS0" } ], "pmid": "" }, { "name": "negative regulation of gluconeogenesis", "id": "GO:0045721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045721", "evidence": [ { "database": "UniProtKB", "id": "F7FMS0", "url": "https://www.uniprot.org/uniprotkb/F7FMS0" } ], "pmid": "" }, { "name": "cellular response to type II interferon", "id": "GO:0071346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071346", "evidence": [ { "database": "UniProtKB", "id": "F7FMS0", "url": "https://www.uniprot.org/uniprotkb/F7FMS0" } ], "pmid": "" }, { "name": "embryo implantation", "id": "GO:0007566", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007566", "evidence": [ { "database": "UniProtKB", "id": "F7FMS0", "url": "https://www.uniprot.org/uniprotkb/F7FMS0" } ], "pmid": "" }, { "name": "mammary gland development", "id": "GO:0030879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030879", "evidence": [ { "database": "UniProtKB", "id": "F7FMS0", "url": "https://www.uniprot.org/uniprotkb/F7FMS0" } ], "pmid": "" }, { "name": "positive regulation of mammary gland epithelial cell proliferation", "id": "GO:0033601", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033601", "evidence": [ { "database": "UniProtKB", "id": "F7FMS0", "url": "https://www.uniprot.org/uniprotkb/F7FMS0" } ], "pmid": "" }, { "name": "mammary duct terminal end bud growth", "id": "GO:0060763", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060763", "evidence": [ { "database": "UniProtKB", "id": "F7FMS0", "url": "https://www.uniprot.org/uniprotkb/F7FMS0" } ], "pmid": "" }, { "name": "regulation of macrophage chemotaxis", "id": "GO:0010758", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010758", "evidence": [ { "database": "UniProtKB", "id": "F7FMS0", "url": "https://www.uniprot.org/uniprotkb/F7FMS0" } ], "pmid": "" }, { "name": "regulation of cAMP-dependent protein kinase activity", "id": "GO:2000479", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000479", "evidence": [ { "database": "UniProtKB", "id": "F7FMS0", "url": "https://www.uniprot.org/uniprotkb/F7FMS0" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "F7FMS0", "url": "https://www.uniprot.org/uniprotkb/F7FMS0" } ], "pmid": "" }, { "name": "vacuole", "id": "GO:0005773", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005773", "evidence": [ { "database": "UniProtKB", "id": "F7FMS0", "url": "https://www.uniprot.org/uniprotkb/F7FMS0" } ], "pmid": "" } ], "molecular_function": [ { "name": "enzyme binding", "id": "GO:0019899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019899", "evidence": [ { "database": "UniProtKB", "id": "F7FMS0", "url": "https://www.uniprot.org/uniprotkb/F7FMS0" } ], "pmid": "" }, { "name": "receptor tyrosine kinase binding", "id": "GO:0030971", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030971", "evidence": [ { "database": "UniProtKB", "id": "F7FMS0", "url": "https://www.uniprot.org/uniprotkb/F7FMS0" } ], "pmid": "" }, { "name": "histone kinase activity", "id": "GO:0035173", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035173", "evidence": [ { "database": "UniProtKB", "id": "F7FMS0", "url": "https://www.uniprot.org/uniprotkb/F7FMS0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F7FMS0-1" }, { "uniprot_canonical_ac": "F8WGA3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F8WGA3", "url": "https://www.uniprot.org/uniprotkb/F8WGA3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 378, "chemical_mass": 42589.0, "gene_names": "Serpinb1b", "protein_name": "Leukocyte elastase inhibitor", "disease": [ { "disease_id": "DOID:13372", "name": "alpha 1-antitrypsin deficiency", "description": "A plasma protein metabolism disease that has_material_basis_in defective production of the protease inhibitor alpha 1-antitrypsin (A1AT), leading to decreased A1AT activity in the blood and lungs, and deposition of excessive abnormal A1AT protein in liver cells.", "url": "https://disease-ontology.org/term/DOID:13372", "evidence": [ { "id": "13372", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13372" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "serine-type endopeptidase inhibitor activity", "id": "GO:0004867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004867", "evidence": [ { "database": "UniProtKB", "id": "F8WGA3", "url": "https://www.uniprot.org/uniprotkb/F8WGA3" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "F8WGA3", "url": "https://www.uniprot.org/uniprotkb/F8WGA3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F8WGA3", "url": "https://www.uniprot.org/uniprotkb/F8WGA3" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of interleukin-1 beta production", "id": "GO:0032691", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032691", "evidence": [ { "database": "UniProtKB", "id": "F8WGA3", "url": "https://www.uniprot.org/uniprotkb/F8WGA3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F8WGA3-1" }, { "uniprot_canonical_ac": "G3V608-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "G3V608", "url": "https://www.uniprot.org/uniprotkb/G3V608" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 896, "chemical_mass": 99432.0, "gene_names": "Csf2rb;Csf2rb1;Csf2rb", "protein_name": "", "disease": [ { "disease_id": "DOID:12120", "name": "pulmonary alveolar proteinosis", "description": "A lung disease that is characterized by abnormal accumulation of surfactant occurs within the alveoli, interfering with gas exchange.", "url": "https://disease-ontology.org/term/DOID:12120", "evidence": [ { "id": "12120", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12120" } ], "weight": 0.0 }, { "disease_id": "DOID:2316", "name": "brain ischemia", "description": "An ischemia that is characterized by insufficient blood flow to the brain to meet metabolic demand.", "url": "https://disease-ontology.org/term/DOID:2316", "evidence": [ { "id": "2316", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2316" } ], "weight": 0.0 }, { "disease_id": "DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.", "url": "https://disease-ontology.org/term/DOID:2841", "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "granulocyte macrophage colony-stimulating factor receptor complex", "id": "GO:0030526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030526", "evidence": [ { "database": "UniProtKB", "id": "G3V608", "url": "https://www.uniprot.org/uniprotkb/G3V608" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G3V608", "url": "https://www.uniprot.org/uniprotkb/G3V608" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "G3V608", "url": "https://www.uniprot.org/uniprotkb/G3V608" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "G3V608", "url": "https://www.uniprot.org/uniprotkb/G3V608" } ], "pmid": "" } ], "biological_process": [ { "name": "interleukin-5-mediated signaling pathway", "id": "GO:0038043", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038043", "evidence": [ { "database": "UniProtKB", "id": "G3V608", "url": "https://www.uniprot.org/uniprotkb/G3V608" } ], "pmid": "" }, { "name": "interleukin-3-mediated signaling pathway", "id": "GO:0038156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038156", "evidence": [ { "database": "UniProtKB", "id": "G3V608", "url": "https://www.uniprot.org/uniprotkb/G3V608" } ], "pmid": "" }, { "name": "response to lipopolysaccharide", "id": "GO:0032496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032496", "evidence": [ { "database": "UniProtKB", "id": "G3V608", "url": "https://www.uniprot.org/uniprotkb/G3V608" } ], "pmid": "" }, { "name": "immunoglobulin mediated immune response", "id": "GO:0016064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016064", "evidence": [ { "database": "UniProtKB", "id": "G3V608", "url": "https://www.uniprot.org/uniprotkb/G3V608" } ], "pmid": "" }, { "name": "cell surface receptor signaling pathway via JAK-STAT", "id": "GO:0007259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007259", "evidence": [ { "database": "UniProtKB", "id": "G3V608", "url": "https://www.uniprot.org/uniprotkb/G3V608" } ], "pmid": "" }, { "name": "positive regulation of leukocyte proliferation", "id": "GO:0070665", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070665", "evidence": [ { "database": "UniProtKB", "id": "G3V608", "url": "https://www.uniprot.org/uniprotkb/G3V608" } ], "pmid": "" }, { "name": "granulocyte-macrophage colony-stimulating factor signaling pathway", "id": "GO:0038157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038157", "evidence": [ { "database": "UniProtKB", "id": "G3V608", "url": "https://www.uniprot.org/uniprotkb/G3V608" } ], "pmid": "" } ], "molecular_function": [ { "name": "coreceptor activity", "id": "GO:0015026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015026", "evidence": [ { "database": "UniProtKB", "id": "G3V608", "url": "https://www.uniprot.org/uniprotkb/G3V608" } ], "pmid": "" }, { "name": "cytokine receptor activity", "id": "GO:0004896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004896", "evidence": [ { "database": "UniProtKB", "id": "G3V608", "url": "https://www.uniprot.org/uniprotkb/G3V608" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "G3V608-1", "start_pos": "712", "end_pos": "712", "site_lbl": "Thr712", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 712, "start_aa": "Thr", "end_pos": 712, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr712", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "G3V608-1" }, { "uniprot_canonical_ac": "G3V8E2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "G3V8E2", "url": "https://www.uniprot.org/uniprotkb/G3V8E2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 892, "chemical_mass": 101586.0, "gene_names": "Strip1", "protein_name": "Striatin-interacting protein 1", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G3V8E2", "url": "https://www.uniprot.org/uniprotkb/G3V8E2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "G3V8E2", "url": "https://www.uniprot.org/uniprotkb/G3V8E2" } ], "pmid": "" }, { "name": "FAR/SIN/STRIPAK complex", "id": "GO:0090443", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090443", "evidence": [ { "database": "UniProtKB", "id": "G3V8E2", "url": "https://www.uniprot.org/uniprotkb/G3V8E2" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "G3V8E2", "url": "https://www.uniprot.org/uniprotkb/G3V8E2" } ], "pmid": "" }, { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "G3V8E2", "url": "https://www.uniprot.org/uniprotkb/G3V8E2" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "G3V8E2", "url": "https://www.uniprot.org/uniprotkb/G3V8E2" } ], "pmid": "" } ], "biological_process": [ { "name": "cytoskeleton organization", "id": "GO:0007010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007010", "evidence": [ { "database": "UniProtKB", "id": "G3V8E2", "url": "https://www.uniprot.org/uniprotkb/G3V8E2" } ], "pmid": "" }, { "name": "negative regulation of hippo signaling", "id": "GO:0035331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035331", "evidence": [ { "database": "UniProtKB", "id": "G3V8E2", "url": "https://www.uniprot.org/uniprotkb/G3V8E2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "G3V8E2-1" }, { "uniprot_canonical_ac": "G3V9L7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "G3V9L7", "url": "https://www.uniprot.org/uniprotkb/G3V9L7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 605, "chemical_mass": 68688.0, "gene_names": "Gdpd5;Gdpd5;RGD1559673", "protein_name": "", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G3V9L7", "url": "https://www.uniprot.org/uniprotkb/G3V9L7" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "G3V9L7", "url": "https://www.uniprot.org/uniprotkb/G3V9L7" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "G3V9L7", "url": "https://www.uniprot.org/uniprotkb/G3V9L7" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "G3V9L7", "url": "https://www.uniprot.org/uniprotkb/G3V9L7" } ], "pmid": "" }, { "name": "perinuclear endoplasmic reticulum", "id": "GO:0097038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097038", "evidence": [ { "database": "UniProtKB", "id": "G3V9L7", "url": "https://www.uniprot.org/uniprotkb/G3V9L7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "G3V9L7", "url": "https://www.uniprot.org/uniprotkb/G3V9L7" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "G3V9L7", "url": "https://www.uniprot.org/uniprotkb/G3V9L7" } ], "pmid": "" } ], "biological_process": [ { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "G3V9L7", "url": "https://www.uniprot.org/uniprotkb/G3V9L7" } ], "pmid": "" }, { "name": "neuron projection development", "id": "GO:0031175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031175", "evidence": [ { "database": "UniProtKB", "id": "G3V9L7", "url": "https://www.uniprot.org/uniprotkb/G3V9L7" } ], "pmid": "" }, { "name": "positive regulation of neuron differentiation", "id": "GO:0045666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045666", "evidence": [ { "database": "UniProtKB", "id": "G3V9L7", "url": "https://www.uniprot.org/uniprotkb/G3V9L7" } ], "pmid": "" }, { "name": "spinal cord motor neuron differentiation", "id": "GO:0021522", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021522", "evidence": [ { "database": "UniProtKB", "id": "G3V9L7", "url": "https://www.uniprot.org/uniprotkb/G3V9L7" } ], "pmid": "" }, { "name": "positive regulation of cell cycle", "id": "GO:0045787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045787", "evidence": [ { "database": "UniProtKB", "id": "G3V9L7", "url": "https://www.uniprot.org/uniprotkb/G3V9L7" } ], "pmid": "" }, { "name": "negative regulation of Notch signaling pathway", "id": "GO:0045746", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045746", "evidence": [ { "database": "UniProtKB", "id": "G3V9L7", "url": "https://www.uniprot.org/uniprotkb/G3V9L7" } ], "pmid": "" }, { "name": "cerebral cortex neuron differentiation", "id": "GO:0021895", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021895", "evidence": [ { "database": "UniProtKB", "id": "G3V9L7", "url": "https://www.uniprot.org/uniprotkb/G3V9L7" } ], "pmid": "" }, { "name": "regulation of timing of cell differentiation", "id": "GO:0048505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048505", "evidence": [ { "database": "UniProtKB", "id": "G3V9L7", "url": "https://www.uniprot.org/uniprotkb/G3V9L7" } ], "pmid": "" }, { "name": "positive regulation of cell differentiation", "id": "GO:0045597", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045597", "evidence": [ { "database": "UniProtKB", "id": "G3V9L7", "url": "https://www.uniprot.org/uniprotkb/G3V9L7" } ], "pmid": "" } ], "molecular_function": [ { "name": "glycerophosphodiester phosphodiesterase activity", "id": "GO:0008889", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008889", "evidence": [ { "database": "UniProtKB", "id": "G3V9L7", "url": "https://www.uniprot.org/uniprotkb/G3V9L7" } ], "pmid": "" }, { "name": "glycerophosphocholine phosphodiesterase activity", "id": "GO:0047389", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047389", "evidence": [ { "database": "UniProtKB", "id": "G3V9L7", "url": "https://www.uniprot.org/uniprotkb/G3V9L7" } ], "pmid": "" }, { "name": "phosphoric diester hydrolase activity", "id": "GO:0008081", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008081", "evidence": [ { "database": "UniProtKB", "id": "G3V9L7", "url": "https://www.uniprot.org/uniprotkb/G3V9L7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "G3V9L7-1" }, { "uniprot_canonical_ac": "M0R3N4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "M0R3N4", "url": "https://www.uniprot.org/uniprotkb/M0R3N4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 417, "chemical_mass": 45817.0, "gene_names": "Vat1l;LOC361414;Vat1l", "protein_name": "NADPH:quinone reductase", "disease": [], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "M0R3N4", "url": "https://www.uniprot.org/uniprotkb/M0R3N4" } ], "pmid": "" }, { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "M0R3N4", "url": "https://www.uniprot.org/uniprotkb/M0R3N4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M0R3N4-1" }, { "uniprot_canonical_ac": "M0R3Q7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "M0R3Q7", "url": "https://www.uniprot.org/uniprotkb/M0R3Q7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 905, "chemical_mass": 101843.0, "gene_names": "Ptchd3;Ptchd3", "protein_name": "Patched domain-containing protein 3", "disease": [], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "M0R3Q7", "url": "https://www.uniprot.org/uniprotkb/M0R3Q7" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "M0R3Q7", "url": "https://www.uniprot.org/uniprotkb/M0R3Q7" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "M0R3Q7", "url": "https://www.uniprot.org/uniprotkb/M0R3Q7" } ], "pmid": "" }, { "name": "sperm midpiece", "id": "GO:0097225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097225", "evidence": [ { "database": "UniProtKB", "id": "M0R3Q7", "url": "https://www.uniprot.org/uniprotkb/M0R3Q7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M0R3Q7-1", "start_pos": "146", "end_pos": "146", "site_lbl": "Asn146", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 146, "start_aa": "Asn", "end_pos": 146, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn146", "evidence": [ { "id": "M0R3Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/M0R3Q7#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "M0R3Q7-1", "start_pos": "199", "end_pos": "199", "site_lbl": "Asn199", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 199, "start_aa": "Asn", "end_pos": 199, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn199", "evidence": [ { "id": "M0R3Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/M0R3Q7#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "M0R3Q7-1", "start_pos": "229", "end_pos": "229", "site_lbl": "Asn229", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 229, "start_aa": "Asn", "end_pos": 229, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn229", "evidence": [ { "id": "M0R3Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/M0R3Q7#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "M0R3Q7-1", "start_pos": "233", "end_pos": "233", "site_lbl": "Asn233", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 233, "start_aa": "Asn", "end_pos": 233, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn233", "evidence": [ { "id": "M0R3Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/M0R3Q7#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "M0R3Q7-1", "start_pos": "647", "end_pos": "647", "site_lbl": "Asn647", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 647, "start_aa": "Asn", "end_pos": 647, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn647", "evidence": [ { "id": "M0R3Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/M0R3Q7#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "M0R3Q7-1", "start_pos": "661", "end_pos": "661", "site_lbl": "Asn661", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 661, "start_aa": "Asn", "end_pos": 661, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn661", "evidence": [ { "id": "M0R3Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/M0R3Q7#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "M0R3Q7-1", "start_pos": "692", "end_pos": "692", "site_lbl": "Asn692", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 692, "start_aa": "Asn", "end_pos": 692, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn692", "evidence": [ { "id": "M0R3Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/M0R3Q7#ptm_processing" } ] } ] } ], "record_id": "M0R3Q7-1" }, { "uniprot_canonical_ac": "M0R3W4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "M0R3W4", "url": "https://www.uniprot.org/uniprotkb/M0R3W4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 461, "chemical_mass": 49821.0, "gene_names": "Zfp296", "protein_name": "Zinc finger protein 296", "disease": [], "molecular_function": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "M0R3W4", "url": "https://www.uniprot.org/uniprotkb/M0R3W4" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "M0R3W4", "url": "https://www.uniprot.org/uniprotkb/M0R3W4" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "M0R3W4", "url": "https://www.uniprot.org/uniprotkb/M0R3W4" } ], "pmid": "" }, { "name": "sequence-specific double-stranded DNA binding", "id": "GO:1990837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990837", "evidence": [ { "database": "UniProtKB", "id": "M0R3W4", "url": "https://www.uniprot.org/uniprotkb/M0R3W4" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "M0R3W4", "url": "https://www.uniprot.org/uniprotkb/M0R3W4" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "M0R3W4", "url": "https://www.uniprot.org/uniprotkb/M0R3W4" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "M0R3W4", "url": "https://www.uniprot.org/uniprotkb/M0R3W4" } ], "pmid": "" }, { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "M0R3W4", "url": "https://www.uniprot.org/uniprotkb/M0R3W4" } ], "pmid": "" }, { "name": "negative regulation of dendrite development", "id": "GO:2000171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000171", "evidence": [ { "database": "UniProtKB", "id": "M0R3W4", "url": "https://www.uniprot.org/uniprotkb/M0R3W4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M0R3W4-1", "start_pos": "312", "end_pos": "312", "site_lbl": "Thr312", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 312, "start_aa": "Thr", "end_pos": 312, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr312", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "M0R3W4-1" }, { "uniprot_canonical_ac": "M0R460-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "M0R460", "url": "https://www.uniprot.org/uniprotkb/M0R460" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 115, "chemical_mass": 13574.0, "gene_names": "AABR07051244.1", "protein_name": "Lipocalin/cytosolic fatty-acid binding domain-containing protein", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "M0R460", "url": "https://www.uniprot.org/uniprotkb/M0R460" } ], "pmid": "" } ], "molecular_function": [ { "name": "small molecule binding", "id": "GO:0036094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036094", "evidence": [ { "database": "UniProtKB", "id": "M0R460", "url": "https://www.uniprot.org/uniprotkb/M0R460" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M0R460-1" }, { "uniprot_canonical_ac": "M0R4G0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "M0R4G0", "url": "https://www.uniprot.org/uniprotkb/M0R4G0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 746, "chemical_mass": 79878.0, "gene_names": "Islr2;Islr2;LOC100910729", "protein_name": "Immunoglobulin superfamily containing leucine-rich repeat protein 2", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "M0R4G0", "url": "https://www.uniprot.org/uniprotkb/M0R4G0" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "M0R4G0", "url": "https://www.uniprot.org/uniprotkb/M0R4G0" } ], "pmid": "" } ], "biological_process": [ { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "M0R4G0", "url": "https://www.uniprot.org/uniprotkb/M0R4G0" } ], "pmid": "" }, { "name": "positive regulation of axon extension", "id": "GO:0045773", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045773", "evidence": [ { "database": "UniProtKB", "id": "M0R4G0", "url": "https://www.uniprot.org/uniprotkb/M0R4G0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M0R4G0-1", "start_pos": "318", "end_pos": "318", "site_lbl": "Thr318", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 318, "start_aa": "Thr", "end_pos": 318, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr318", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "M0R4G0-1", "start_pos": "320", "end_pos": "320", "site_lbl": "Thr320", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 320, "start_aa": "Thr", "end_pos": 320, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr320", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "M0R4G0-1" }, { "uniprot_canonical_ac": "M0R4W5-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "M0R4W5", "url": "https://www.uniprot.org/uniprotkb/M0R4W5" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 310, "chemical_mass": 33584.0, "gene_names": "Lysmd4;LOC681647;Lysmd4", "protein_name": "LysM and putative peptidoglycan-binding domain-containing protein 4", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "M0R4W5", "url": "https://www.uniprot.org/uniprotkb/M0R4W5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M0R4W5-1" }, { "uniprot_canonical_ac": "M0R528-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "M0R528", "url": "https://www.uniprot.org/uniprotkb/M0R528" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 172, "chemical_mass": 20197.0, "gene_names": "Exoc1l;Exoc1l;LOC686911", "protein_name": "Exocyst complex component 1-like", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M0R528-1" }, { "uniprot_canonical_ac": "M0R581-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "M0R581", "url": "https://www.uniprot.org/uniprotkb/M0R581" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 144, "chemical_mass": 16579.0, "gene_names": "Ankrd40cl", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M0R581-1" }, { "uniprot_canonical_ac": "M0R5J6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "M0R5J6", "url": "https://www.uniprot.org/uniprotkb/M0R5J6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 566, "chemical_mass": 62315.0, "gene_names": "Srrm5;AABR07002689.1;Srrm5", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M0R5J6-1", "start_pos": "34", "end_pos": "34", "site_lbl": "Thr34", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 34, "start_aa": "Thr", "end_pos": 34, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr34", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "M0R5J6-1", "start_pos": "45", "end_pos": "45", "site_lbl": "Thr45", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 45, "start_aa": "Thr", "end_pos": 45, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr45", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "M0R5J6-1" }, { "uniprot_canonical_ac": "M0R5R8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "M0R5R8", "url": "https://www.uniprot.org/uniprotkb/M0R5R8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 403, "chemical_mass": 40411.0, "gene_names": "Nkx1-1", "protein_name": "NK1 transcription factor-related protein 1", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "M0R5R8", "url": "https://www.uniprot.org/uniprotkb/M0R5R8" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "M0R5R8", "url": "https://www.uniprot.org/uniprotkb/M0R5R8" } ], "pmid": "" }, { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "M0R5R8", "url": "https://www.uniprot.org/uniprotkb/M0R5R8" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "M0R5R8", "url": "https://www.uniprot.org/uniprotkb/M0R5R8" } ], "pmid": "" }, { "name": "regulation of glucose metabolic process", "id": "GO:0010906", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010906", "evidence": [ { "database": "UniProtKB", "id": "M0R5R8", "url": "https://www.uniprot.org/uniprotkb/M0R5R8" } ], "pmid": "" }, { "name": "nervous system process", "id": "GO:0050877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050877", "evidence": [ { "database": "UniProtKB", "id": "M0R5R8", "url": "https://www.uniprot.org/uniprotkb/M0R5R8" } ], "pmid": "" }, { "name": "regulation of generation of precursor metabolites and energy", "id": "GO:0043467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043467", "evidence": [ { "database": "UniProtKB", "id": "M0R5R8", "url": "https://www.uniprot.org/uniprotkb/M0R5R8" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "M0R5R8", "url": "https://www.uniprot.org/uniprotkb/M0R5R8" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "M0R5R8", "url": "https://www.uniprot.org/uniprotkb/M0R5R8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M0R5R8-1" }, { "uniprot_canonical_ac": "M0R5Z2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "M0R5Z2", "url": "https://www.uniprot.org/uniprotkb/M0R5Z2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 230, "chemical_mass": 23600.0, "gene_names": "Frat2;Frat2;LOC679110", "protein_name": "", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "M0R5Z2", "url": "https://www.uniprot.org/uniprotkb/M0R5Z2" } ], "pmid": "" } ], "biological_process": [ { "name": "Wnt signaling pathway", "id": "GO:0016055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055", "evidence": [ { "database": "UniProtKB", "id": "M0R5Z2", "url": "https://www.uniprot.org/uniprotkb/M0R5Z2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M0R5Z2-1" }, { "uniprot_canonical_ac": "M0R6A8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "M0R6A8", "url": "https://www.uniprot.org/uniprotkb/M0R6A8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 357, "chemical_mass": 41873.0, "gene_names": "AABR07013425.1", "protein_name": "LINE-1 retrotransposable element ORF1 protein", "disease": [], "biological_process": [ { "name": "retrotransposition", "id": "GO:0032197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032197", "evidence": [ { "database": "UniProtKB", "id": "M0R6A8", "url": "https://www.uniprot.org/uniprotkb/M0R6A8" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "M0R6A8", "url": "https://www.uniprot.org/uniprotkb/M0R6A8" } ], "pmid": "" }, { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "M0R6A8", "url": "https://www.uniprot.org/uniprotkb/M0R6A8" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "M0R6A8", "url": "https://www.uniprot.org/uniprotkb/M0R6A8" } ], "pmid": "" } ], "molecular_function": [ { "name": "nucleotide binding", "id": "GO:0000166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000166", "evidence": [ { "database": "UniProtKB", "id": "M0R6A8", "url": "https://www.uniprot.org/uniprotkb/M0R6A8" } ], "pmid": "" }, { "name": "single-stranded RNA binding", "id": "GO:0003727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003727", "evidence": [ { "database": "UniProtKB", "id": "M0R6A8", "url": "https://www.uniprot.org/uniprotkb/M0R6A8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M0R6A8-1" }, { "uniprot_canonical_ac": "M0R6D8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "M0R6D8", "url": "https://www.uniprot.org/uniprotkb/M0R6D8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 403, "chemical_mass": 41184.0, "gene_names": "Mnx1;Hlxb9;Mnx1", "protein_name": "Motor neuron and pancreas homeobox 1", "disease": [ { "disease_id": "DOID:0111546", "name": "Currarino syndrome", "description": "A syndrome characterized by anorectal malformations, a presacral mass, and partial sacral agenesis with intact first sacral vertebra that has_material_basis_in heterozygous mutation in HLXB9 on chromosome 7q36.3.", "url": "https://disease-ontology.org/term/DOID:0111546", "evidence": [ { "id": "0111546", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111546" } ], "weight": 0.0 } ], "biological_process": [ { "name": "spinal cord motor neuron cell fate specification", "id": "GO:0021520", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021520", "evidence": [ { "database": "UniProtKB", "id": "M0R6D8", "url": "https://www.uniprot.org/uniprotkb/M0R6D8" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "M0R6D8", "url": "https://www.uniprot.org/uniprotkb/M0R6D8" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "M0R6D8", "url": "https://www.uniprot.org/uniprotkb/M0R6D8" } ], "pmid": "" }, { "name": "neuron migration", "id": "GO:0001764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001764", "evidence": [ { "database": "UniProtKB", "id": "M0R6D8", "url": "https://www.uniprot.org/uniprotkb/M0R6D8" } ], "pmid": "" }, { "name": "neuron projection morphogenesis", "id": "GO:0048812", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048812", "evidence": [ { "database": "UniProtKB", "id": "M0R6D8", "url": "https://www.uniprot.org/uniprotkb/M0R6D8" } ], "pmid": "" }, { "name": "central nervous system development", "id": "GO:0007417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007417", "evidence": [ { "database": "UniProtKB", "id": "M0R6D8", "url": "https://www.uniprot.org/uniprotkb/M0R6D8" } ], "pmid": "" }, { "name": "post-embryonic development", "id": "GO:0009791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009791", "evidence": [ { "database": "UniProtKB", "id": "M0R6D8", "url": "https://www.uniprot.org/uniprotkb/M0R6D8" } ], "pmid": "" }, { "name": "neuron differentiation", "id": "GO:0030182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030182", "evidence": [ { "database": "UniProtKB", "id": "M0R6D8", "url": "https://www.uniprot.org/uniprotkb/M0R6D8" } ], "pmid": "" }, { "name": "pancreas development", "id": "GO:0031016", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031016", "evidence": [ { "database": "UniProtKB", "id": "M0R6D8", "url": "https://www.uniprot.org/uniprotkb/M0R6D8" } ], "pmid": "" }, { "name": "nerve development", "id": "GO:0021675", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021675", "evidence": [ { "database": "UniProtKB", "id": "M0R6D8", "url": "https://www.uniprot.org/uniprotkb/M0R6D8" } ], "pmid": "" }, { "name": "endocrine pancreas development", "id": "GO:0031018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031018", "evidence": [ { "database": "UniProtKB", "id": "M0R6D8", "url": "https://www.uniprot.org/uniprotkb/M0R6D8" } ], "pmid": "" }, { "name": "respiratory system development", "id": "GO:0060541", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060541", "evidence": [ { "database": "UniProtKB", "id": "M0R6D8", "url": "https://www.uniprot.org/uniprotkb/M0R6D8" } ], "pmid": "" }, { "name": "central nervous system neuron differentiation", "id": "GO:0021953", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021953", "evidence": [ { "database": "UniProtKB", "id": "M0R6D8", "url": "https://www.uniprot.org/uniprotkb/M0R6D8" } ], "pmid": "" }, { "name": "motor neuron axon guidance", "id": "GO:0008045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008045", "evidence": [ { "database": "UniProtKB", "id": "M0R6D8", "url": "https://www.uniprot.org/uniprotkb/M0R6D8" } ], "pmid": "" }, { "name": "cell morphogenesis involved in neuron differentiation", "id": "GO:0048667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048667", "evidence": [ { "database": "UniProtKB", "id": "M0R6D8", "url": "https://www.uniprot.org/uniprotkb/M0R6D8" } ], "pmid": "" }, { "name": "dorsal/ventral neural tube patterning", "id": "GO:0021904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021904", "evidence": [ { "database": "UniProtKB", "id": "M0R6D8", "url": "https://www.uniprot.org/uniprotkb/M0R6D8" } ], "pmid": "" }, { "name": "diaphragm development", "id": "GO:0060539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060539", "evidence": [ { "database": "UniProtKB", "id": "M0R6D8", "url": "https://www.uniprot.org/uniprotkb/M0R6D8" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "M0R6D8", "url": "https://www.uniprot.org/uniprotkb/M0R6D8" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "M0R6D8", "url": "https://www.uniprot.org/uniprotkb/M0R6D8" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "M0R6D8", "url": "https://www.uniprot.org/uniprotkb/M0R6D8" } ], "pmid": "" }, { "name": "sequence-specific double-stranded DNA binding", "id": "GO:1990837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990837", "evidence": [ { "database": "UniProtKB", "id": "M0R6D8", "url": "https://www.uniprot.org/uniprotkb/M0R6D8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M0R6D8-1", "start_pos": "37", "end_pos": "37", "site_lbl": "Thr37", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 37, "start_aa": "Thr", "end_pos": 37, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr37", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "M0R6D8-1", "start_pos": "78", "end_pos": "78", "site_lbl": "Ser78", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "M0R6D8", "url": "https://www.uniprot.org/uniprotkb/M0R6D8" } ] } ] }, { "uniprot_canonical_ac": "M0R6D8-1", "start_pos": "80", "end_pos": "80", "site_lbl": "Ser80", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "M0R6D8", "url": "https://www.uniprot.org/uniprotkb/M0R6D8" } ] } ] } ], "record_id": "M0R6D8-1" }, { "uniprot_canonical_ac": "M0R6R9-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "M0R6R9", "url": "https://www.uniprot.org/uniprotkb/M0R6R9" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 276, "chemical_mass": 29418.0, "gene_names": "LOC134484068;LOC134484068;Tsga8", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M0R6R9-1" }, { "uniprot_canonical_ac": "M0R6S5-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "M0R6S5", "url": "https://www.uniprot.org/uniprotkb/M0R6S5" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 886, "chemical_mass": 100187.0, "gene_names": "Chsy3;Chsy3l;Chsy3;RGD1560819", "protein_name": "Hexosyltransferase", "disease": [], "cellular_component": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "M0R6S5", "url": "https://www.uniprot.org/uniprotkb/M0R6S5" } ], "pmid": "" }, { "name": "Golgi cisterna membrane", "id": "GO:0032580", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032580", "evidence": [ { "database": "UniProtKB", "id": "M0R6S5", "url": "https://www.uniprot.org/uniprotkb/M0R6S5" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "M0R6S5", "url": "https://www.uniprot.org/uniprotkb/M0R6S5" } ], "pmid": "" }, { "name": "N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity", "id": "GO:0050510", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050510", "evidence": [ { "database": "UniProtKB", "id": "M0R6S5", "url": "https://www.uniprot.org/uniprotkb/M0R6S5" } ], "pmid": "" }, { "name": "glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity", "id": "GO:0047238", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047238", "evidence": [ { "database": "UniProtKB", "id": "M0R6S5", "url": "https://www.uniprot.org/uniprotkb/M0R6S5" } ], "pmid": "" } ], "biological_process": [ { "name": "chondroitin sulfate proteoglycan biosynthetic process", "id": "GO:0050650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050650", "evidence": [ { "database": "UniProtKB", "id": "M0R6S5", "url": "https://www.uniprot.org/uniprotkb/M0R6S5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M0R6S5-1", "start_pos": "166", "end_pos": "166", "site_lbl": "Thr166", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 166, "start_aa": "Thr", "end_pos": 166, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr166", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "M0R6S5-1" }, { "uniprot_canonical_ac": "M0R6T4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "M0R6T4", "url": "https://www.uniprot.org/uniprotkb/M0R6T4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1031, "chemical_mass": 112932.0, "gene_names": "Mms19;Mms19l;Mms19", "protein_name": "MMS19 nucleotide excision repair protein", "disease": [], "biological_process": [ { "name": "iron-sulfur cluster assembly", "id": "GO:0016226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016226", "evidence": [ { "database": "UniProtKB", "id": "M0R6T4", "url": "https://www.uniprot.org/uniprotkb/M0R6T4" } ], "pmid": "" }, { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "M0R6T4", "url": "https://www.uniprot.org/uniprotkb/M0R6T4" } ], "pmid": "" }, { "name": "protein maturation", "id": "GO:0051604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051604", "evidence": [ { "database": "UniProtKB", "id": "M0R6T4", "url": "https://www.uniprot.org/uniprotkb/M0R6T4" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosolic [4Fe-4S] assembly targeting complex", "id": "GO:0097361", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097361", "evidence": [ { "database": "UniProtKB", "id": "M0R6T4", "url": "https://www.uniprot.org/uniprotkb/M0R6T4" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "M0R6T4", "url": "https://www.uniprot.org/uniprotkb/M0R6T4" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "M0R6T4", "url": "https://www.uniprot.org/uniprotkb/M0R6T4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "M0R6T4", "url": "https://www.uniprot.org/uniprotkb/M0R6T4" } ], "pmid": "" }, { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "M0R6T4", "url": "https://www.uniprot.org/uniprotkb/M0R6T4" } ], "pmid": "" }, { "name": "MMXD complex", "id": "GO:0071817", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071817", "evidence": [ { "database": "UniProtKB", "id": "M0R6T4", "url": "https://www.uniprot.org/uniprotkb/M0R6T4" } ], "pmid": "" } ], "molecular_function": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "M0R6T4", "url": "https://www.uniprot.org/uniprotkb/M0R6T4" } ], "pmid": "" }, { "name": "enzyme binding", "id": "GO:0019899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019899", "evidence": [ { "database": "UniProtKB", "id": "M0R6T4", "url": "https://www.uniprot.org/uniprotkb/M0R6T4" } ], "pmid": "" }, { "name": "nuclear estrogen receptor binding", "id": "GO:0030331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030331", "evidence": [ { "database": "UniProtKB", "id": "M0R6T4", "url": "https://www.uniprot.org/uniprotkb/M0R6T4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M0R6T4-1" }, { "uniprot_canonical_ac": "M0R7C6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "M0R7C6", "url": "https://www.uniprot.org/uniprotkb/M0R7C6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 381, "chemical_mass": 41136.0, "gene_names": "Ankrd33", "protein_name": "", "disease": [], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "M0R7C6", "url": "https://www.uniprot.org/uniprotkb/M0R7C6" } ], "pmid": "" }, { "name": "skeletal muscle cell differentiation", "id": "GO:0035914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035914", "evidence": [ { "database": "UniProtKB", "id": "M0R7C6", "url": "https://www.uniprot.org/uniprotkb/M0R7C6" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "M0R7C6", "url": "https://www.uniprot.org/uniprotkb/M0R7C6" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "M0R7C6", "url": "https://www.uniprot.org/uniprotkb/M0R7C6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M0R7C6-1" }, { "uniprot_canonical_ac": "M0R7G2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "M0R7G2", "url": "https://www.uniprot.org/uniprotkb/M0R7G2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1456, "chemical_mass": 170586.0, "gene_names": "AABR07043115.1", "protein_name": "LINE-1 retrotransposable element ORF1 protein", "disease": [], "molecular_function": [ { "name": "RNA-directed DNA polymerase activity", "id": "GO:0003964", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003964", "evidence": [ { "database": "UniProtKB", "id": "M0R7G2", "url": "https://www.uniprot.org/uniprotkb/M0R7G2" } ], "pmid": "" }, { "name": "nucleotide binding", "id": "GO:0000166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000166", "evidence": [ { "database": "UniProtKB", "id": "M0R7G2", "url": "https://www.uniprot.org/uniprotkb/M0R7G2" } ], "pmid": "" } ], "biological_process": [ { "name": "retrotransposition", "id": "GO:0032197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032197", "evidence": [ { "database": "UniProtKB", "id": "M0R7G2", "url": "https://www.uniprot.org/uniprotkb/M0R7G2" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "M0R7G2", "url": "https://www.uniprot.org/uniprotkb/M0R7G2" } ], "pmid": "" }, { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "M0R7G2", "url": "https://www.uniprot.org/uniprotkb/M0R7G2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M0R7G2-1" }, { "uniprot_canonical_ac": "M0R7V3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "M0R7V3", "url": "https://www.uniprot.org/uniprotkb/M0R7V3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 198, "chemical_mass": 22629.0, "gene_names": "Apoo;Apoo;RGD1565289", "protein_name": "MICOS complex subunit", "disease": [ { "disease_id": "DOID:225", "name": "syndrome", "description": "A disease characterized by a group of signs and symptoms that occur together and characterize a particular abnormality.", "url": "https://disease-ontology.org/term/DOID:225", "evidence": [ { "id": "225", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:225" } ], "weight": 0.0 } ], "biological_process": [ { "name": "cristae formation", "id": "GO:0042407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042407", "evidence": [ { "database": "UniProtKB", "id": "M0R7V3", "url": "https://www.uniprot.org/uniprotkb/M0R7V3" } ], "pmid": "" } ], "cellular_component": [ { "name": "MICOS complex", "id": "GO:0061617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061617", "evidence": [ { "database": "UniProtKB", "id": "M0R7V3", "url": "https://www.uniprot.org/uniprotkb/M0R7V3" } ], "pmid": "" }, { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "M0R7V3", "url": "https://www.uniprot.org/uniprotkb/M0R7V3" } ], "pmid": "" }, { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "M0R7V3", "url": "https://www.uniprot.org/uniprotkb/M0R7V3" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "M0R7V3", "url": "https://www.uniprot.org/uniprotkb/M0R7V3" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "M0R7V3", "url": "https://www.uniprot.org/uniprotkb/M0R7V3" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "M0R7V3", "url": "https://www.uniprot.org/uniprotkb/M0R7V3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M0R7V3-1" }, { "uniprot_canonical_ac": "M0R7Q2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "M0R7Q2", "url": "https://www.uniprot.org/uniprotkb/M0R7Q2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 105, "chemical_mass": 11927.0, "gene_names": "ENSRNOG00000065283", "protein_name": "Ig-like domain-containing protein", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "M0R7Q2", "url": "https://www.uniprot.org/uniprotkb/M0R7Q2" } ], "pmid": "" }, { "name": "immunoglobulin complex", "id": "GO:0019814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019814", "evidence": [ { "database": "UniProtKB", "id": "M0R7Q2", "url": "https://www.uniprot.org/uniprotkb/M0R7Q2" } ], "pmid": "" } ], "molecular_function": [ { "name": "antigen binding", "id": "GO:0003823", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003823", "evidence": [ { "database": "UniProtKB", "id": "M0R7Q2", "url": "https://www.uniprot.org/uniprotkb/M0R7Q2" } ], "pmid": "" } ], "biological_process": [ { "name": "immunoglobulin mediated immune response", "id": "GO:0016064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016064", "evidence": [ { "database": "UniProtKB", "id": "M0R7Q2", "url": "https://www.uniprot.org/uniprotkb/M0R7Q2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M0R7Q2-1" }, { "uniprot_canonical_ac": "M0R7S3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "M0R7S3", "url": "https://www.uniprot.org/uniprotkb/M0R7S3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 136, "chemical_mass": 14820.0, "gene_names": "Trav6-1", "protein_name": "", "disease": [], "cellular_component": [ { "name": "T cell receptor complex", "id": "GO:0042101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042101", "evidence": [ { "database": "UniProtKB", "id": "M0R7S3", "url": "https://www.uniprot.org/uniprotkb/M0R7S3" } ], "pmid": "" }, { "name": "immunoglobulin complex", "id": "GO:0019814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019814", "evidence": [ { "database": "UniProtKB", "id": "M0R7S3", "url": "https://www.uniprot.org/uniprotkb/M0R7S3" } ], "pmid": "" } ], "biological_process": [ { "name": "adaptive immune response", "id": "GO:0002250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002250", "evidence": [ { "database": "UniProtKB", "id": "M0R7S3", "url": "https://www.uniprot.org/uniprotkb/M0R7S3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M0R7S3-1" }, { "uniprot_canonical_ac": "M0R7S5-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "M0R7S5", "url": "https://www.uniprot.org/uniprotkb/M0R7S5" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1490, "chemical_mass": 150887.0, "gene_names": "Plin4;Plin4", "protein_name": "Perilipin-4", "disease": [], "cellular_component": [ { "name": "lipid droplet", "id": "GO:0005811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005811", "evidence": [ { "database": "UniProtKB", "id": "M0R7S5", "url": "https://www.uniprot.org/uniprotkb/M0R7S5" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "M0R7S5", "url": "https://www.uniprot.org/uniprotkb/M0R7S5" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "M0R7S5", "url": "https://www.uniprot.org/uniprotkb/M0R7S5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M0R7S5-1", "start_pos": "378", "end_pos": "378", "site_lbl": "Thr378", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 378, "start_aa": "Thr", "end_pos": 378, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr378", "evidence": [ { "id": "28657654", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/28657654" }, { "id": "M0R7S5", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/M0R7S5" } ] } ] } ], "record_id": "M0R7S5-1" }, { "uniprot_canonical_ac": "M0R7U8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "M0R7U8", "url": "https://www.uniprot.org/uniprotkb/M0R7U8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 314, "chemical_mass": 35038.0, "gene_names": "Or5g27;Olr443;Or5g27", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "M0R7U8", "url": "https://www.uniprot.org/uniprotkb/M0R7U8" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "M0R7U8", "url": "https://www.uniprot.org/uniprotkb/M0R7U8" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "M0R7U8", "url": "https://www.uniprot.org/uniprotkb/M0R7U8" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "M0R7U8", "url": "https://www.uniprot.org/uniprotkb/M0R7U8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M0R7U8-1" }, { "uniprot_canonical_ac": "M0R7V5-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "M0R7V5", "url": "https://www.uniprot.org/uniprotkb/M0R7V5" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 777, "chemical_mass": 87861.0, "gene_names": "Tnfaip3;LOC683206;Tnfaip3", "protein_name": "Tumor necrosis factor alpha-induced protein 3", "disease": [ { "disease_id": "DOID:0080944", "name": "familial Behcet-like autoinflammatory syndrome", "description": "An autoinflammatory disease that is characterized by characterized by ulceration of mucosal surfaces, particularly in the oral and genital areas and that has_material_basis_in heterozygous mutation in the TNFAIP3 gene on chromosome 6q23.", "url": "https://disease-ontology.org/term/DOID:0080944", "evidence": [ { "id": "0080944", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080944" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:219", "name": "colon cancer", "description": "A colorectal cancer that is located_in the colon.", "url": "https://disease-ontology.org/term/DOID:219", "evidence": [ { "id": "219", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:219" } ], "weight": 0.0 }, { "disease_id": "DOID:3748", "name": "esophagus squamous cell carcinoma", "description": "An esophageal carcinoma that derives_from epithelial squamous cells located_in the esophagus.", "url": "https://disease-ontology.org/term/DOID:3748", "evidence": [ { "id": "3748", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3748" } ], "weight": 0.0 }, { "disease_id": "DOID:4947", "name": "cholangiocarcinoma", "description": "A bile duct adenocarcinoma that has_material_basis_in bile duct epithelial cells.", "url": "https://disease-ontology.org/term/DOID:4947", "evidence": [ { "id": "4947", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4947" } ], "weight": 0.0 }, { "disease_id": "DOID:5041", "name": "esophageal cancer", "description": "A gastrointestinal system cancer that is located_in the esophagus.", "url": "https://disease-ontology.org/term/DOID:5041", "evidence": [ { "id": "5041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5041" } ], "weight": 0.0 }, { "disease_id": "DOID:5517", "name": "stomach carcinoma", "description": "A stomach cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:5517", "evidence": [ { "id": "5517", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5517" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:8577", "name": "ulcerative colitis", "description": "A colitis that is predominantly confined to the mucosa located_in colon and includes characteristic ulcers, or open sores.", "url": "https://disease-ontology.org/term/DOID:8577", "evidence": [ { "id": "8577", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8577" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 }, { "disease_id": "DOID:9261", "name": "nasopharynx carcinoma", "description": "A pharynx cancer that is located in the nasopharynx, the uppermost region of the pharynx or throat, where the nasal passages and auditory tubes join the remainder of the upper respiratory tract.", "url": "https://disease-ontology.org/term/DOID:9261", "evidence": [ { "id": "9261", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9261" } ], "weight": 0.0 } ], "biological_process": [ { "name": "positive regulation of hepatocyte proliferation", "id": "GO:2000347", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000347", "evidence": [ { "database": "UniProtKB", "id": "M0R7V5", "url": "https://www.uniprot.org/uniprotkb/M0R7V5" } ], "pmid": "" }, { "name": "negative regulation of chronic inflammatory response", "id": "GO:0002677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002677", "evidence": [ { "database": "UniProtKB", "id": "M0R7V5", "url": "https://www.uniprot.org/uniprotkb/M0R7V5" } ], "pmid": "" }, { "name": "negative regulation of interleukin-2 production", "id": "GO:0032703", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032703", "evidence": [ { "database": "UniProtKB", "id": "M0R7V5", "url": "https://www.uniprot.org/uniprotkb/M0R7V5" } ], "pmid": "" }, { "name": "tolerance induction to lipopolysaccharide", "id": "GO:0072573", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072573", "evidence": [ { "database": "UniProtKB", "id": "M0R7V5", "url": "https://www.uniprot.org/uniprotkb/M0R7V5" } ], "pmid": "" }, { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "M0R7V5", "url": "https://www.uniprot.org/uniprotkb/M0R7V5" } ], "pmid": "" }, { "name": "inflammatory response", "id": "GO:0006954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006954", "evidence": [ { "database": "UniProtKB", "id": "M0R7V5", "url": "https://www.uniprot.org/uniprotkb/M0R7V5" } ], "pmid": "" }, { "name": "protein deubiquitination", "id": "GO:0016579", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016579", "evidence": [ { "database": "UniProtKB", "id": "M0R7V5", "url": "https://www.uniprot.org/uniprotkb/M0R7V5" } ], "pmid": "" }, { "name": "protein K63-linked deubiquitination", "id": "GO:0070536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070536", "evidence": [ { "database": "UniProtKB", "id": "M0R7V5", "url": "https://www.uniprot.org/uniprotkb/M0R7V5" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "M0R7V5", "url": "https://www.uniprot.org/uniprotkb/M0R7V5" } ], "pmid": "" }, { "name": "negative regulation of interleukin-1 beta production", "id": "GO:0032691", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032691", "evidence": [ { "database": "UniProtKB", "id": "M0R7V5", "url": "https://www.uniprot.org/uniprotkb/M0R7V5" } ], "pmid": "" }, { "name": "negative regulation of interleukin-6 production", "id": "GO:0032715", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032715", "evidence": [ { "database": "UniProtKB", "id": "M0R7V5", "url": "https://www.uniprot.org/uniprotkb/M0R7V5" } ], "pmid": "" }, { "name": "negative regulation of tumor necrosis factor production", "id": "GO:0032720", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032720", "evidence": [ { "database": "UniProtKB", "id": "M0R7V5", "url": "https://www.uniprot.org/uniprotkb/M0R7V5" } ], "pmid": "" }, { "name": "negative regulation of inflammatory response", "id": "GO:0050728", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050728", "evidence": [ { "database": "UniProtKB", "id": "M0R7V5", "url": "https://www.uniprot.org/uniprotkb/M0R7V5" } ], "pmid": "" }, { "name": "cellular response to lipopolysaccharide", "id": "GO:0071222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071222", "evidence": [ { "database": "UniProtKB", "id": "M0R7V5", "url": "https://www.uniprot.org/uniprotkb/M0R7V5" } ], "pmid": "" }, { "name": "B-1 B cell homeostasis", "id": "GO:0001922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001922", "evidence": [ { "database": "UniProtKB", "id": "M0R7V5", "url": "https://www.uniprot.org/uniprotkb/M0R7V5" } ], "pmid": "" }, { "name": "negative regulation of canonical NF-kappaB signal transduction", "id": "GO:0043124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043124", "evidence": [ { "database": "UniProtKB", "id": "M0R7V5", "url": "https://www.uniprot.org/uniprotkb/M0R7V5" } ], "pmid": "" }, { "name": "cellular response to hydrogen peroxide", "id": "GO:0070301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070301", "evidence": [ { "database": "UniProtKB", "id": "M0R7V5", "url": "https://www.uniprot.org/uniprotkb/M0R7V5" } ], "pmid": "" }, { "name": "negative regulation of endothelial cell apoptotic process", "id": "GO:2000352", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000352", "evidence": [ { "database": "UniProtKB", "id": "M0R7V5", "url": "https://www.uniprot.org/uniprotkb/M0R7V5" } ], "pmid": "" }, { "name": "positive regulation of protein catabolic process", "id": "GO:0045732", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045732", "evidence": [ { "database": "UniProtKB", "id": "M0R7V5", "url": "https://www.uniprot.org/uniprotkb/M0R7V5" } ], "pmid": "" }, { "name": "negative regulation of smooth muscle cell proliferation", "id": "GO:0048662", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048662", "evidence": [ { "database": "UniProtKB", "id": "M0R7V5", "url": "https://www.uniprot.org/uniprotkb/M0R7V5" } ], "pmid": "" }, { "name": "negative regulation of extrinsic apoptotic signaling pathway", "id": "GO:2001237", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001237", "evidence": [ { "database": "UniProtKB", "id": "M0R7V5", "url": "https://www.uniprot.org/uniprotkb/M0R7V5" } ], "pmid": "" }, { "name": "negative regulation of protein ubiquitination", "id": "GO:0031397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031397", "evidence": [ { "database": "UniProtKB", "id": "M0R7V5", "url": "https://www.uniprot.org/uniprotkb/M0R7V5" } ], "pmid": "" }, { "name": "protein K48-linked ubiquitination", "id": "GO:0070936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070936", "evidence": [ { "database": "UniProtKB", "id": "M0R7V5", "url": "https://www.uniprot.org/uniprotkb/M0R7V5" } ], "pmid": "" }, { "name": "negative regulation of extrinsic apoptotic signaling pathway via death domain receptors", "id": "GO:1902042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902042", "evidence": [ { "database": "UniProtKB", "id": "M0R7V5", "url": "https://www.uniprot.org/uniprotkb/M0R7V5" } ], "pmid": "" }, { "name": "negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway", "id": "GO:0070433", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070433", "evidence": [ { "database": "UniProtKB", "id": "M0R7V5", "url": "https://www.uniprot.org/uniprotkb/M0R7V5" } ], "pmid": "" }, { "name": "negative regulation of CD40 signaling pathway", "id": "GO:2000349", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000349", "evidence": [ { "database": "UniProtKB", "id": "M0R7V5", "url": "https://www.uniprot.org/uniprotkb/M0R7V5" } ], "pmid": "" }, { "name": "response to molecule of bacterial origin", "id": "GO:0002237", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002237", "evidence": [ { "database": "UniProtKB", "id": "M0R7V5", "url": "https://www.uniprot.org/uniprotkb/M0R7V5" } ], "pmid": "" }, { "name": "protein K48-linked deubiquitination", "id": "GO:0071108", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071108", "evidence": [ { "database": "UniProtKB", "id": "M0R7V5", "url": "https://www.uniprot.org/uniprotkb/M0R7V5" } ], "pmid": "" }, { "name": "regulation of germinal center formation", "id": "GO:0002634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002634", "evidence": [ { "database": "UniProtKB", "id": "M0R7V5", "url": "https://www.uniprot.org/uniprotkb/M0R7V5" } ], "pmid": "" }, { "name": "negative regulation of B cell activation", "id": "GO:0050869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050869", "evidence": [ { "database": "UniProtKB", "id": "M0R7V5", "url": "https://www.uniprot.org/uniprotkb/M0R7V5" } ], "pmid": "" }, { "name": "negative regulation of innate immune response", "id": "GO:0045824", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045824", "evidence": [ { "database": "UniProtKB", "id": "M0R7V5", "url": "https://www.uniprot.org/uniprotkb/M0R7V5" } ], "pmid": "" }, { "name": "response to muramyl dipeptide", "id": "GO:0032495", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032495", "evidence": [ { "database": "UniProtKB", "id": "M0R7V5", "url": "https://www.uniprot.org/uniprotkb/M0R7V5" } ], "pmid": "" }, { "name": "negative regulation of toll-like receptor 3 signaling pathway", "id": "GO:0034140", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034140", "evidence": [ { "database": "UniProtKB", "id": "M0R7V5", "url": "https://www.uniprot.org/uniprotkb/M0R7V5" } ], "pmid": "" }, { "name": "protein K11-linked deubiquitination", "id": "GO:0035871", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035871", "evidence": [ { "database": "UniProtKB", "id": "M0R7V5", "url": "https://www.uniprot.org/uniprotkb/M0R7V5" } ], "pmid": "" }, { "name": "negative regulation of toll-like receptor 5 signaling pathway", "id": "GO:0034148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034148", "evidence": [ { "database": "UniProtKB", "id": "M0R7V5", "url": "https://www.uniprot.org/uniprotkb/M0R7V5" } ], "pmid": "" }, { "name": "negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway", "id": "GO:0070429", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070429", "evidence": [ { "database": "UniProtKB", "id": "M0R7V5", "url": "https://www.uniprot.org/uniprotkb/M0R7V5" } ], "pmid": "" }, { "name": "establishment of protein localization to vacuole", "id": "GO:0072666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072666", "evidence": [ { "database": "UniProtKB", "id": "M0R7V5", "url": "https://www.uniprot.org/uniprotkb/M0R7V5" } ], "pmid": "" } ], "molecular_function": [ { "name": "protease binding", "id": "GO:0002020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002020", "evidence": [ { "database": "UniProtKB", "id": "M0R7V5", "url": "https://www.uniprot.org/uniprotkb/M0R7V5" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "M0R7V5", "url": "https://www.uniprot.org/uniprotkb/M0R7V5" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "M0R7V5", "url": "https://www.uniprot.org/uniprotkb/M0R7V5" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "M0R7V5", "url": "https://www.uniprot.org/uniprotkb/M0R7V5" } ], "pmid": "" }, { "name": "kinase binding", "id": "GO:0019900", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019900", "evidence": [ { "database": "UniProtKB", "id": "M0R7V5", "url": "https://www.uniprot.org/uniprotkb/M0R7V5" } ], "pmid": "" }, { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "M0R7V5", "url": "https://www.uniprot.org/uniprotkb/M0R7V5" } ], "pmid": "" }, { "name": "ubiquitin binding", "id": "GO:0043130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043130", "evidence": [ { "database": "UniProtKB", "id": "M0R7V5", "url": "https://www.uniprot.org/uniprotkb/M0R7V5" } ], "pmid": "" }, { "name": "cysteine-type deubiquitinase activity", "id": "GO:0004843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004843", "evidence": [ { "database": "UniProtKB", "id": "M0R7V5", "url": "https://www.uniprot.org/uniprotkb/M0R7V5" } ], "pmid": "" }, { "name": "K63-linked deubiquitinase activity", "id": "GO:0061578", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061578", "evidence": [ { "database": "UniProtKB", "id": "M0R7V5", "url": "https://www.uniprot.org/uniprotkb/M0R7V5" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "M0R7V5", "url": "https://www.uniprot.org/uniprotkb/M0R7V5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "M0R7V5", "url": "https://www.uniprot.org/uniprotkb/M0R7V5" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "M0R7V5", "url": "https://www.uniprot.org/uniprotkb/M0R7V5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M0R7V5-1", "start_pos": "740", "end_pos": "740", "site_lbl": "Thr740", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 740, "start_aa": "Thr", "end_pos": 740, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr740", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "M0R7V5-1" }, { "uniprot_canonical_ac": "M0R885-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "M0R885", "url": "https://www.uniprot.org/uniprotkb/M0R885" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 558, "chemical_mass": 63622.0, "gene_names": "Lin9", "protein_name": "", "disease": [], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "M0R885", "url": "https://www.uniprot.org/uniprotkb/M0R885" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "M0R885", "url": "https://www.uniprot.org/uniprotkb/M0R885" } ], "pmid": "" }, { "name": "transcription repressor complex", "id": "GO:0017053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017053", "evidence": [ { "database": "UniProtKB", "id": "M0R885", "url": "https://www.uniprot.org/uniprotkb/M0R885" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "M0R885", "url": "https://www.uniprot.org/uniprotkb/M0R885" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "M0R885", "url": "https://www.uniprot.org/uniprotkb/M0R885" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "M0R885", "url": "https://www.uniprot.org/uniprotkb/M0R885" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "M0R885", "url": "https://www.uniprot.org/uniprotkb/M0R885" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M0R885-1" }, { "uniprot_canonical_ac": "M0R890-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "M0R890", "url": "https://www.uniprot.org/uniprotkb/M0R890" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1627, "chemical_mass": 183971.0, "gene_names": "Abca6;Abca6", "protein_name": "", "disease": [], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "M0R890", "url": "https://www.uniprot.org/uniprotkb/M0R890" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "M0R890", "url": "https://www.uniprot.org/uniprotkb/M0R890" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "M0R890", "url": "https://www.uniprot.org/uniprotkb/M0R890" } ], "pmid": "" } ], "molecular_function": [ { "name": "lipid transporter activity", "id": "GO:0005319", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005319", "evidence": [ { "database": "UniProtKB", "id": "M0R890", "url": "https://www.uniprot.org/uniprotkb/M0R890" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "M0R890", "url": "https://www.uniprot.org/uniprotkb/M0R890" } ], "pmid": "" }, { "name": "ATPase-coupled transmembrane transporter activity", "id": "GO:0042626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042626", "evidence": [ { "database": "UniProtKB", "id": "M0R890", "url": "https://www.uniprot.org/uniprotkb/M0R890" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "M0R890", "url": "https://www.uniprot.org/uniprotkb/M0R890" } ], "pmid": "" }, { "name": "ABC-type transporter activity", "id": "GO:0140359", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140359", "evidence": [ { "database": "UniProtKB", "id": "M0R890", "url": "https://www.uniprot.org/uniprotkb/M0R890" } ], "pmid": "" } ], "biological_process": [ { "name": "lipid transport", "id": "GO:0006869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006869", "evidence": [ { "database": "UniProtKB", "id": "M0R890", "url": "https://www.uniprot.org/uniprotkb/M0R890" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M0R890-1" }, { "uniprot_canonical_ac": "M0R8P6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "M0R8P6", "url": "https://www.uniprot.org/uniprotkb/M0R8P6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1380, "chemical_mass": 155420.0, "gene_names": "Wwc3", "protein_name": "", "disease": [], "biological_process": [ { "name": "negative regulation of organ growth", "id": "GO:0046621", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046621", "evidence": [ { "database": "UniProtKB", "id": "M0R8P6", "url": "https://www.uniprot.org/uniprotkb/M0R8P6" } ], "pmid": "" }, { "name": "regulation of hippo signaling", "id": "GO:0035330", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035330", "evidence": [ { "database": "UniProtKB", "id": "M0R8P6", "url": "https://www.uniprot.org/uniprotkb/M0R8P6" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "M0R8P6", "url": "https://www.uniprot.org/uniprotkb/M0R8P6" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "M0R8P6", "url": "https://www.uniprot.org/uniprotkb/M0R8P6" } ], "pmid": "" }, { "name": "negative regulation of cell population proliferation", "id": "GO:0008285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008285", "evidence": [ { "database": "UniProtKB", "id": "M0R8P6", "url": "https://www.uniprot.org/uniprotkb/M0R8P6" } ], "pmid": "" }, { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "M0R8P6", "url": "https://www.uniprot.org/uniprotkb/M0R8P6" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "M0R8P6", "url": "https://www.uniprot.org/uniprotkb/M0R8P6" } ], "pmid": "" }, { "name": "hippo signaling", "id": "GO:0035329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035329", "evidence": [ { "database": "UniProtKB", "id": "M0R8P6", "url": "https://www.uniprot.org/uniprotkb/M0R8P6" } ], "pmid": "" }, { "name": "negative regulation of hippo signaling", "id": "GO:0035331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035331", "evidence": [ { "database": "UniProtKB", "id": "M0R8P6", "url": "https://www.uniprot.org/uniprotkb/M0R8P6" } ], "pmid": "" } ], "molecular_function": [ { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "M0R8P6", "url": "https://www.uniprot.org/uniprotkb/M0R8P6" } ], "pmid": "" }, { "name": "kinase binding", "id": "GO:0019900", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019900", "evidence": [ { "database": "UniProtKB", "id": "M0R8P6", "url": "https://www.uniprot.org/uniprotkb/M0R8P6" } ], "pmid": "" }, { "name": "signaling adaptor activity", "id": "GO:0035591", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035591", "evidence": [ { "database": "UniProtKB", "id": "M0R8P6", "url": "https://www.uniprot.org/uniprotkb/M0R8P6" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "M0R8P6", "url": "https://www.uniprot.org/uniprotkb/M0R8P6" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "M0R8P6", "url": "https://www.uniprot.org/uniprotkb/M0R8P6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M0R8P6-1", "start_pos": "830", "end_pos": "830", "site_lbl": "Thr830", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 830, "start_aa": "Thr", "end_pos": 830, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr830", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "M0R8P6-1" }, { "uniprot_canonical_ac": "M0R8W9-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "M0R8W9", "url": "https://www.uniprot.org/uniprotkb/M0R8W9" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1020, "chemical_mass": 108517.0, "gene_names": "Cd177;Cd177;RGD1562941", "protein_name": "", "disease": [], "molecular_function": [ { "name": "protease binding", "id": "GO:0002020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002020", "evidence": [ { "database": "UniProtKB", "id": "M0R8W9", "url": "https://www.uniprot.org/uniprotkb/M0R8W9" } ], "pmid": "" }, { "name": "integrin binding", "id": "GO:0005178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005178", "evidence": [ { "database": "UniProtKB", "id": "M0R8W9", "url": "https://www.uniprot.org/uniprotkb/M0R8W9" } ], "pmid": "" }, { "name": "calcium-dependent protein binding", "id": "GO:0048306", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048306", "evidence": [ { "database": "UniProtKB", "id": "M0R8W9", "url": "https://www.uniprot.org/uniprotkb/M0R8W9" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "M0R8W9", "url": "https://www.uniprot.org/uniprotkb/M0R8W9" } ], "pmid": "" }, { "name": "plasma membrane raft", "id": "GO:0044853", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044853", "evidence": [ { "database": "UniProtKB", "id": "M0R8W9", "url": "https://www.uniprot.org/uniprotkb/M0R8W9" } ], "pmid": "" }, { "name": "tertiary granule membrane", "id": "GO:0070821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070821", "evidence": [ { "database": "UniProtKB", "id": "M0R8W9", "url": "https://www.uniprot.org/uniprotkb/M0R8W9" } ], "pmid": "" }, { "name": "secretory granule membrane", "id": "GO:0030667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030667", "evidence": [ { "database": "UniProtKB", "id": "M0R8W9", "url": "https://www.uniprot.org/uniprotkb/M0R8W9" } ], "pmid": "" } ], "biological_process": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "M0R8W9", "url": "https://www.uniprot.org/uniprotkb/M0R8W9" } ], "pmid": "" }, { "name": "regulation of endocytosis", "id": "GO:0030100", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030100", "evidence": [ { "database": "UniProtKB", "id": "M0R8W9", "url": "https://www.uniprot.org/uniprotkb/M0R8W9" } ], "pmid": "" }, { "name": "positive regulation of superoxide anion generation", "id": "GO:0032930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032930", "evidence": [ { "database": "UniProtKB", "id": "M0R8W9", "url": "https://www.uniprot.org/uniprotkb/M0R8W9" } ], "pmid": "" }, { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "M0R8W9", "url": "https://www.uniprot.org/uniprotkb/M0R8W9" } ], "pmid": "" }, { "name": "leukocyte cell-cell adhesion", "id": "GO:0007159", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007159", "evidence": [ { "database": "UniProtKB", "id": "M0R8W9", "url": "https://www.uniprot.org/uniprotkb/M0R8W9" } ], "pmid": "" }, { "name": "protein localization to cell surface", "id": "GO:0034394", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034394", "evidence": [ { "database": "UniProtKB", "id": "M0R8W9", "url": "https://www.uniprot.org/uniprotkb/M0R8W9" } ], "pmid": "" }, { "name": "regulation of integrin-mediated signaling pathway", "id": "GO:2001044", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001044", "evidence": [ { "database": "UniProtKB", "id": "M0R8W9", "url": "https://www.uniprot.org/uniprotkb/M0R8W9" } ], "pmid": "" }, { "name": "positive regulation of neutrophil degranulation", "id": "GO:0043315", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043315", "evidence": [ { "database": "UniProtKB", "id": "M0R8W9", "url": "https://www.uniprot.org/uniprotkb/M0R8W9" } ], "pmid": "" }, { "name": "cell-cell junction maintenance", "id": "GO:0045217", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045217", "evidence": [ { "database": "UniProtKB", "id": "M0R8W9", "url": "https://www.uniprot.org/uniprotkb/M0R8W9" } ], "pmid": "" }, { "name": "neutrophil extravasation", "id": "GO:0072672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072672", "evidence": [ { "database": "UniProtKB", "id": "M0R8W9", "url": "https://www.uniprot.org/uniprotkb/M0R8W9" } ], "pmid": "" }, { "name": "neutrophil migration", "id": "GO:1990266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990266", "evidence": [ { "database": "UniProtKB", "id": "M0R8W9", "url": "https://www.uniprot.org/uniprotkb/M0R8W9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M0R8W9-1" }, { "uniprot_canonical_ac": "M0R9C6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "M0R9C6", "url": "https://www.uniprot.org/uniprotkb/M0R9C6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 646, "chemical_mass": 72371.0, "gene_names": "Ddx43;Ddx43;LOC682138", "protein_name": "RNA helicase", "disease": [], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "M0R9C6", "url": "https://www.uniprot.org/uniprotkb/M0R9C6" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "M0R9C6", "url": "https://www.uniprot.org/uniprotkb/M0R9C6" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "M0R9C6", "url": "https://www.uniprot.org/uniprotkb/M0R9C6" } ], "pmid": "" }, { "name": "RNA helicase activity", "id": "GO:0003724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003724", "evidence": [ { "database": "UniProtKB", "id": "M0R9C6", "url": "https://www.uniprot.org/uniprotkb/M0R9C6" } ], "pmid": "" } ], "biological_process": [ { "name": "myoblast differentiation", "id": "GO:0045445", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045445", "evidence": [ { "database": "UniProtKB", "id": "M0R9C6", "url": "https://www.uniprot.org/uniprotkb/M0R9C6" } ], "pmid": "" }, { "name": "miRNA transcription", "id": "GO:0061614", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061614", "evidence": [ { "database": "UniProtKB", "id": "M0R9C6", "url": "https://www.uniprot.org/uniprotkb/M0R9C6" } ], "pmid": "" }, { "name": "alternative mRNA splicing, via spliceosome", "id": "GO:0000380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000380", "evidence": [ { "database": "UniProtKB", "id": "M0R9C6", "url": "https://www.uniprot.org/uniprotkb/M0R9C6" } ], "pmid": "" }, { "name": "regulation of alternative mRNA splicing, via spliceosome", "id": "GO:0000381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000381", "evidence": [ { "database": "UniProtKB", "id": "M0R9C6", "url": "https://www.uniprot.org/uniprotkb/M0R9C6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M0R9C6-1" }, { "uniprot_canonical_ac": "M0R9G4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "M0R9G4", "url": "https://www.uniprot.org/uniprotkb/M0R9G4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1635, "chemical_mass": 186096.0, "gene_names": "Rtl1", "protein_name": "", "disease": [], "biological_process": [ { "name": "angiogenesis", "id": "GO:0001525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001525", "evidence": [ { "database": "UniProtKB", "id": "M0R9G4", "url": "https://www.uniprot.org/uniprotkb/M0R9G4" } ], "pmid": "" }, { "name": "placenta development", "id": "GO:0001890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001890", "evidence": [ { "database": "UniProtKB", "id": "M0R9G4", "url": "https://www.uniprot.org/uniprotkb/M0R9G4" } ], "pmid": "" }, { "name": "embryonic placenta development", "id": "GO:0001892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001892", "evidence": [ { "database": "UniProtKB", "id": "M0R9G4", "url": "https://www.uniprot.org/uniprotkb/M0R9G4" } ], "pmid": "" }, { "name": "skeletal muscle tissue development", "id": "GO:0007519", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007519", "evidence": [ { "database": "UniProtKB", "id": "M0R9G4", "url": "https://www.uniprot.org/uniprotkb/M0R9G4" } ], "pmid": "" }, { "name": "gene expression", "id": "GO:0010467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010467", "evidence": [ { "database": "UniProtKB", "id": "M0R9G4", "url": "https://www.uniprot.org/uniprotkb/M0R9G4" } ], "pmid": "" }, { "name": "labyrinthine layer development", "id": "GO:0060711", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060711", "evidence": [ { "database": "UniProtKB", "id": "M0R9G4", "url": "https://www.uniprot.org/uniprotkb/M0R9G4" } ], "pmid": "" }, { "name": "skeletal muscle satellite cell proliferation", "id": "GO:0014841", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014841", "evidence": [ { "database": "UniProtKB", "id": "M0R9G4", "url": "https://www.uniprot.org/uniprotkb/M0R9G4" } ], "pmid": "" } ], "cellular_component": [ { "name": "Z disc", "id": "GO:0030018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030018", "evidence": [ { "database": "UniProtKB", "id": "M0R9G4", "url": "https://www.uniprot.org/uniprotkb/M0R9G4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M0R9G4-1" }, { "uniprot_canonical_ac": "M0R9L0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "M0R9L0", "url": "https://www.uniprot.org/uniprotkb/M0R9L0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 2163, "chemical_mass": 220197.0, "gene_names": "Naca;Naca", "protein_name": "", "disease": [], "molecular_function": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "M0R9L0", "url": "https://www.uniprot.org/uniprotkb/M0R9L0" } ], "pmid": "" }, { "name": "unfolded protein binding", "id": "GO:0051082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051082", "evidence": [ { "database": "UniProtKB", "id": "M0R9L0", "url": "https://www.uniprot.org/uniprotkb/M0R9L0" } ], "pmid": "" }, { "name": "TBP-class protein binding", "id": "GO:0017025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017025", "evidence": [ { "database": "UniProtKB", "id": "M0R9L0", "url": "https://www.uniprot.org/uniprotkb/M0R9L0" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "M0R9L0", "url": "https://www.uniprot.org/uniprotkb/M0R9L0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "M0R9L0", "url": "https://www.uniprot.org/uniprotkb/M0R9L0" } ], "pmid": "" }, { "name": "nascent polypeptide-associated complex", "id": "GO:0005854", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005854", "evidence": [ { "database": "UniProtKB", "id": "M0R9L0", "url": "https://www.uniprot.org/uniprotkb/M0R9L0" } ], "pmid": "" } ], "biological_process": [ { "name": "protein targeting to membrane", "id": "GO:0006612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006612", "evidence": [ { "database": "UniProtKB", "id": "M0R9L0", "url": "https://www.uniprot.org/uniprotkb/M0R9L0" } ], "pmid": "" }, { "name": "myoblast migration", "id": "GO:0051451", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051451", "evidence": [ { "database": "UniProtKB", "id": "M0R9L0", "url": "https://www.uniprot.org/uniprotkb/M0R9L0" } ], "pmid": "" }, { "name": "negative regulation of protein localization to endoplasmic reticulum", "id": "GO:1905551", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905551", "evidence": [ { "database": "UniProtKB", "id": "M0R9L0", "url": "https://www.uniprot.org/uniprotkb/M0R9L0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M0R9L0-1", "start_pos": "1109", "end_pos": "1109", "site_lbl": "Thr1109", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1109, "start_aa": "Thr", "end_pos": 1109, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1109", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "M0R9L0-1", "start_pos": "1233", "end_pos": "1233", "site_lbl": "Thr1233", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1233, "start_aa": "Thr", "end_pos": 1233, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1233", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "M0R9L0-1", "start_pos": "1438", "end_pos": "1438", "site_lbl": "Thr1438", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1438, "start_aa": "Thr", "end_pos": 1438, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1438", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "M0R9L0-1", "start_pos": "1619", "end_pos": "1619", "site_lbl": "Thr1619", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1619, "start_aa": "Thr", "end_pos": 1619, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1619", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "M0R9L0-1" }, { "uniprot_canonical_ac": "M0R9N8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "M0R9N8", "url": "https://www.uniprot.org/uniprotkb/M0R9N8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1058, "chemical_mass": 116893.0, "gene_names": "Anlnl1", "protein_name": "Anillin", "disease": [ { "disease_id": "DOID:0111133", "name": "focal segmental glomerulosclerosis 8", "description": "A focal segmental glomerulosclerosis that has_material_basis_in an autosomal dominant mutation of the ANLN gene on chromosome 7p14.2.", "url": "https://disease-ontology.org/term/DOID:0111133", "evidence": [ { "id": "0111133", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111133" } ], "weight": 0.0 } ], "biological_process": [ { "name": "mitotic cytokinesis", "id": "GO:0000281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000281", "evidence": [ { "database": "UniProtKB", "id": "M0R9N8", "url": "https://www.uniprot.org/uniprotkb/M0R9N8" } ], "pmid": "" }, { "name": "actomyosin contractile ring assembly", "id": "GO:0000915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000915", "evidence": [ { "database": "UniProtKB", "id": "M0R9N8", "url": "https://www.uniprot.org/uniprotkb/M0R9N8" } ], "pmid": "" }, { "name": "septin ring organization", "id": "GO:0031106", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031106", "evidence": [ { "database": "UniProtKB", "id": "M0R9N8", "url": "https://www.uniprot.org/uniprotkb/M0R9N8" } ], "pmid": "" } ], "cellular_component": [ { "name": "actomyosin contractile ring", "id": "GO:0005826", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005826", "evidence": [ { "database": "UniProtKB", "id": "M0R9N8", "url": "https://www.uniprot.org/uniprotkb/M0R9N8" } ], "pmid": "" }, { "name": "bleb", "id": "GO:0032059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032059", "evidence": [ { "database": "UniProtKB", "id": "M0R9N8", "url": "https://www.uniprot.org/uniprotkb/M0R9N8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M0R9N8-1" }, { "uniprot_canonical_ac": "M0RA38-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "M0RA38", "url": "https://www.uniprot.org/uniprotkb/M0RA38" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1048, "chemical_mass": 119317.0, "gene_names": "Nlrp2;LOC684545;Nlrp2", "protein_name": "", "disease": [ { "disease_id": "DOID:3590", "name": "gestational trophoblastic neoplasm", "description": "", "url": "https://disease-ontology.org/term/DOID:3590", "evidence": [ { "id": "3590", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3590" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "M0RA38", "url": "https://www.uniprot.org/uniprotkb/M0RA38" } ], "pmid": "" }, { "name": "Pyrin domain binding", "id": "GO:0032090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032090", "evidence": [ { "database": "UniProtKB", "id": "M0RA38", "url": "https://www.uniprot.org/uniprotkb/M0RA38" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "M0RA38", "url": "https://www.uniprot.org/uniprotkb/M0RA38" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "M0RA38", "url": "https://www.uniprot.org/uniprotkb/M0RA38" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "M0RA38", "url": "https://www.uniprot.org/uniprotkb/M0RA38" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of inflammatory response", "id": "GO:0050727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050727", "evidence": [ { "database": "UniProtKB", "id": "M0RA38", "url": "https://www.uniprot.org/uniprotkb/M0RA38" } ], "pmid": "" }, { "name": "negative regulation of non-canonical NF-kappaB signal transduction", "id": "GO:1901223", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901223", "evidence": [ { "database": "UniProtKB", "id": "M0RA38", "url": "https://www.uniprot.org/uniprotkb/M0RA38" } ], "pmid": "" }, { "name": "positive regulation of interleukin-1 beta production", "id": "GO:0032731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032731", "evidence": [ { "database": "UniProtKB", "id": "M0RA38", "url": "https://www.uniprot.org/uniprotkb/M0RA38" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M0RA38-1" }, { "uniprot_canonical_ac": "M0RAB0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "M0RAB0", "url": "https://www.uniprot.org/uniprotkb/M0RAB0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 256, "chemical_mass": 28884.0, "gene_names": "LOC102551255;LOC102551255", "protein_name": "Tetraspanin", "disease": [ { "disease_id": "DOID:0112024", "name": "non-syndromic X-linked intellectual disability 58", "description": "A non-syndromic X-linked intellectual disability characterized by mild to moderate intellectual disability and no consistent dysmorphic features that has_material_basis_in hemizygous mutation in the TSPAN7 gene on chromosome Xp11.4.", "url": "https://disease-ontology.org/term/DOID:0112024", "evidence": [ { "id": "0112024", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112024" } ], "weight": 0.0 }, { "disease_id": "DOID:1289", "name": "neurodegenerative disease", "description": "A central nervous system disease that results in the progressive deterioration of function or structure of neurons.", "url": "https://disease-ontology.org/term/DOID:1289", "evidence": [ { "id": "1289", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1289" } ], "weight": 0.0 }, { "disease_id": "DOID:14330", "name": "Parkinson's disease", "description": "A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.", "url": "https://disease-ontology.org/term/DOID:14330", "evidence": [ { "id": "14330", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14330" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "M0RAB0", "url": "https://www.uniprot.org/uniprotkb/M0RAB0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M0RAB0-1" }, { "uniprot_canonical_ac": "M0RAR1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "M0RAR1", "url": "https://www.uniprot.org/uniprotkb/M0RAR1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 336, "chemical_mass": 38292.0, "gene_names": "Or51t1;Olfr574;Or51t1;RGD1563481", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "M0RAR1", "url": "https://www.uniprot.org/uniprotkb/M0RAR1" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "M0RAR1", "url": "https://www.uniprot.org/uniprotkb/M0RAR1" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "M0RAR1", "url": "https://www.uniprot.org/uniprotkb/M0RAR1" } ], "pmid": "" } ], "biological_process": [ { "name": "cellular response to lipid", "id": "GO:0071396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071396", "evidence": [ { "database": "UniProtKB", "id": "M0RAR1", "url": "https://www.uniprot.org/uniprotkb/M0RAR1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M0RAR1-1" }, { "uniprot_canonical_ac": "M0RB05-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "M0RB05", "url": "https://www.uniprot.org/uniprotkb/M0RB05" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 252, "chemical_mass": 27132.0, "gene_names": "C10h17orf99;C10h17orf99;LOC688282", "protein_name": "", "disease": [], "molecular_function": [ { "name": "transmembrane signaling receptor activity", "id": "GO:0004888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004888", "evidence": [ { "database": "UniProtKB", "id": "M0RB05", "url": "https://www.uniprot.org/uniprotkb/M0RB05" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "M0RB05", "url": "https://www.uniprot.org/uniprotkb/M0RB05" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "M0RB05", "url": "https://www.uniprot.org/uniprotkb/M0RB05" } ], "pmid": "" } ], "biological_process": [ { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "M0RB05", "url": "https://www.uniprot.org/uniprotkb/M0RB05" } ], "pmid": "" }, { "name": "cell surface receptor signaling pathway", "id": "GO:0007166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007166", "evidence": [ { "database": "UniProtKB", "id": "M0RB05", "url": "https://www.uniprot.org/uniprotkb/M0RB05" } ], "pmid": "" }, { "name": "positive regulation of immunoglobulin production in mucosal tissue", "id": "GO:2000558", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000558", "evidence": [ { "database": "UniProtKB", "id": "M0RB05", "url": "https://www.uniprot.org/uniprotkb/M0RB05" } ], "pmid": "" }, { "name": "mature B cell differentiation involved in immune response", "id": "GO:0002313", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002313", "evidence": [ { "database": "UniProtKB", "id": "M0RB05", "url": "https://www.uniprot.org/uniprotkb/M0RB05" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M0RB05-1", "start_pos": "139", "end_pos": "139", "site_lbl": "Thr139", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 139, "start_aa": "Thr", "end_pos": 139, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr139", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "M0RB05-1" }, { "uniprot_canonical_ac": "M0RBE7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "M0RBE7", "url": "https://www.uniprot.org/uniprotkb/M0RBE7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1118, "chemical_mass": 127016.0, "gene_names": "AABR07063276.1", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M0RBE7-1" }, { "uniprot_canonical_ac": "M0RBR5-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "M0RBR5", "url": "https://www.uniprot.org/uniprotkb/M0RBR5" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 335, "chemical_mass": 38124.0, "gene_names": "Or51a41;Olr72;Or51a41", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "M0RBR5", "url": "https://www.uniprot.org/uniprotkb/M0RBR5" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "M0RBR5", "url": "https://www.uniprot.org/uniprotkb/M0RBR5" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "M0RBR5", "url": "https://www.uniprot.org/uniprotkb/M0RBR5" } ], "pmid": "" } ], "biological_process": [ { "name": "cellular response to lipid", "id": "GO:0071396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071396", "evidence": [ { "database": "UniProtKB", "id": "M0RBR5", "url": "https://www.uniprot.org/uniprotkb/M0RBR5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M0RBR5-1" }, { "uniprot_canonical_ac": "M0RC58-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "M0RC58", "url": "https://www.uniprot.org/uniprotkb/M0RC58" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 773, "chemical_mass": 89562.0, "gene_names": "Dpy19l2;Dpy19l2;Dyp19l2;RGD1564311", "protein_name": "", "disease": [ { "disease_id": "DOID:0111156", "name": "spermatogenic failure 9", "description": "A male infertility characterized by round-headed spermatozoa lacking an acrosome and that has_material_basis_in autosomal recessive inheritance in a mutation in the DPY19L2 gene on chromosome 12q14.", "url": "https://disease-ontology.org/term/DOID:0111156", "evidence": [ { "id": "0111156", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111156" } ], "weight": 0.0 } ], "biological_process": [ { "name": "spermatid development", "id": "GO:0007286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007286", "evidence": [ { "database": "UniProtKB", "id": "M0RC58", "url": "https://www.uniprot.org/uniprotkb/M0RC58" } ], "pmid": "" } ], "molecular_function": [ { "name": "glycosyltransferase activity", "id": "GO:0016757", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016757", "evidence": [ { "database": "UniProtKB", "id": "M0RC58", "url": "https://www.uniprot.org/uniprotkb/M0RC58" } ], "pmid": "" }, { "name": "mannosyltransferase activity", "id": "GO:0000030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000030", "evidence": [ { "database": "UniProtKB", "id": "M0RC58", "url": "https://www.uniprot.org/uniprotkb/M0RC58" } ], "pmid": "" } ], "cellular_component": [ { "name": "nuclear inner membrane", "id": "GO:0005637", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005637", "evidence": [ { "database": "UniProtKB", "id": "M0RC58", "url": "https://www.uniprot.org/uniprotkb/M0RC58" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "M0RC58", "url": "https://www.uniprot.org/uniprotkb/M0RC58" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M0RC58-1" }, { "uniprot_canonical_ac": "M0RCK0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "M0RCK0", "url": "https://www.uniprot.org/uniprotkb/M0RCK0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 883, "chemical_mass": 100608.0, "gene_names": "Zfp658;LOC102546648;RGD1561832;Zfp658", "protein_name": "", "disease": [], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "M0RCK0", "url": "https://www.uniprot.org/uniprotkb/M0RCK0" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "M0RCK0", "url": "https://www.uniprot.org/uniprotkb/M0RCK0" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "M0RCK0", "url": "https://www.uniprot.org/uniprotkb/M0RCK0" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "M0RCK0", "url": "https://www.uniprot.org/uniprotkb/M0RCK0" } ], "pmid": "" }, { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "M0RCK0", "url": "https://www.uniprot.org/uniprotkb/M0RCK0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M0RCK0-1" }, { "uniprot_canonical_ac": "M0RCU5-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "M0RCU5", "url": "https://www.uniprot.org/uniprotkb/M0RCU5" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 214, "chemical_mass": 24479.0, "gene_names": "Urad;Urad", "protein_name": "2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase", "disease": [], "biological_process": [ { "name": "urate catabolic process", "id": "GO:0019628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019628", "evidence": [ { "database": "UniProtKB", "id": "M0RCU5", "url": "https://www.uniprot.org/uniprotkb/M0RCU5" } ], "pmid": "" }, { "name": "purine nucleobase metabolic process", "id": "GO:0006144", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006144", "evidence": [ { "database": "UniProtKB", "id": "M0RCU5", "url": "https://www.uniprot.org/uniprotkb/M0RCU5" } ], "pmid": "" }, { "name": "allantoin metabolic process", "id": "GO:0000255", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000255", "evidence": [ { "database": "UniProtKB", "id": "M0RCU5", "url": "https://www.uniprot.org/uniprotkb/M0RCU5" } ], "pmid": "" } ], "cellular_component": [ { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "M0RCU5", "url": "https://www.uniprot.org/uniprotkb/M0RCU5" } ], "pmid": "" } ], "molecular_function": [ { "name": "carboxy-lyase activity", "id": "GO:0016831", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016831", "evidence": [ { "database": "UniProtKB", "id": "M0RCU5", "url": "https://www.uniprot.org/uniprotkb/M0RCU5" } ], "pmid": "" }, { "name": "2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase activity", "id": "GO:0051997", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051997", "evidence": [ { "database": "UniProtKB", "id": "M0RCU5", "url": "https://www.uniprot.org/uniprotkb/M0RCU5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M0RCU5-1" }, { "uniprot_canonical_ac": "M0RCY4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "M0RCY4", "url": "https://www.uniprot.org/uniprotkb/M0RCY4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 246, "chemical_mass": 27597.0, "gene_names": "AABR07000137.1", "protein_name": "Retinoic acid early-inducible protein 1 domain-containing protein", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "M0RCY4", "url": "https://www.uniprot.org/uniprotkb/M0RCY4" } ], "pmid": "" }, { "name": "side of membrane", "id": "GO:0098552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098552", "evidence": [ { "database": "UniProtKB", "id": "M0RCY4", "url": "https://www.uniprot.org/uniprotkb/M0RCY4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M0RCY4-1" }, { "uniprot_canonical_ac": "M0RD60-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "M0RD60", "url": "https://www.uniprot.org/uniprotkb/M0RD60" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 173, "chemical_mass": 20096.0, "gene_names": "Tmem217;LOC687483", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M0RD60-1" }, { "uniprot_canonical_ac": "M0RD67-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "M0RD67", "url": "https://www.uniprot.org/uniprotkb/M0RD67" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 889, "chemical_mass": 103580.0, "gene_names": "Zfp748;Zfp748", "protein_name": "", "disease": [], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "M0RD67", "url": "https://www.uniprot.org/uniprotkb/M0RD67" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "M0RD67", "url": "https://www.uniprot.org/uniprotkb/M0RD67" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "M0RD67", "url": "https://www.uniprot.org/uniprotkb/M0RD67" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "M0RD67", "url": "https://www.uniprot.org/uniprotkb/M0RD67" } ], "pmid": "" }, { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "M0RD67", "url": "https://www.uniprot.org/uniprotkb/M0RD67" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "M0RD67", "url": "https://www.uniprot.org/uniprotkb/M0RD67" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M0RD67-1" }, { "uniprot_canonical_ac": "M0RDI3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "M0RDI3", "url": "https://www.uniprot.org/uniprotkb/M0RDI3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 405, "chemical_mass": 44771.0, "gene_names": "LOC100911055;LOC100911055", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "M0RDI3", "url": "https://www.uniprot.org/uniprotkb/M0RDI3" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "M0RDI3", "url": "https://www.uniprot.org/uniprotkb/M0RDI3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M0RDI3-1" }, { "uniprot_canonical_ac": "Q5J3E7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "Q5J3E7", "url": "https://www.uniprot.org/uniprotkb/Q5J3E7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 307, "chemical_mass": 35131.0, "gene_names": "Vom1r106;V1re13;Vom1r106", "protein_name": "Vomeronasal type-1 receptor", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q5J3E7", "url": "https://www.uniprot.org/uniprotkb/Q5J3E7" } ], "pmid": "" } ], "biological_process": [ { "name": "response to pheromone", "id": "GO:0019236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019236", "evidence": [ { "database": "UniProtKB", "id": "Q5J3E7", "url": "https://www.uniprot.org/uniprotkb/Q5J3E7" } ], "pmid": "" }, { "name": "sensory perception of chemical stimulus", "id": "GO:0007606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007606", "evidence": [ { "database": "UniProtKB", "id": "Q5J3E7", "url": "https://www.uniprot.org/uniprotkb/Q5J3E7" } ], "pmid": "" } ], "molecular_function": [ { "name": "pheromone binding", "id": "GO:0005550", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005550", "evidence": [ { "database": "UniProtKB", "id": "Q5J3E7", "url": "https://www.uniprot.org/uniprotkb/Q5J3E7" } ], "pmid": "" }, { "name": "pheromone receptor activity", "id": "GO:0016503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016503", "evidence": [ { "database": "UniProtKB", "id": "Q5J3E7", "url": "https://www.uniprot.org/uniprotkb/Q5J3E7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q5J3E7-1" }, { "uniprot_canonical_ac": "Q5J3F5-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "Q5J3F5", "url": "https://www.uniprot.org/uniprotkb/Q5J3F5" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 302, "chemical_mass": 34386.0, "gene_names": "Vom1r22", "protein_name": "Vomeronasal type-1 receptor", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q5J3F5", "url": "https://www.uniprot.org/uniprotkb/Q5J3F5" } ], "pmid": "" } ], "biological_process": [ { "name": "response to pheromone", "id": "GO:0019236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019236", "evidence": [ { "database": "UniProtKB", "id": "Q5J3F5", "url": "https://www.uniprot.org/uniprotkb/Q5J3F5" } ], "pmid": "" }, { "name": "sensory perception of chemical stimulus", "id": "GO:0007606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007606", "evidence": [ { "database": "UniProtKB", "id": "Q5J3F5", "url": "https://www.uniprot.org/uniprotkb/Q5J3F5" } ], "pmid": "" } ], "molecular_function": [ { "name": "pheromone binding", "id": "GO:0005550", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005550", "evidence": [ { "database": "UniProtKB", "id": "Q5J3F5", "url": "https://www.uniprot.org/uniprotkb/Q5J3F5" } ], "pmid": "" }, { "name": "pheromone receptor activity", "id": "GO:0016503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016503", "evidence": [ { "database": "UniProtKB", "id": "Q5J3F5", "url": "https://www.uniprot.org/uniprotkb/Q5J3F5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q5J3F5-1" }, { "uniprot_canonical_ac": "Q5J3K1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "Q5J3K1", "url": "https://www.uniprot.org/uniprotkb/Q5J3K1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 315, "chemical_mass": 36617.0, "gene_names": "Vom1r62;V1rk2;Vom1r62", "protein_name": "Vomeronasal type-1 receptor", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q5J3K1", "url": "https://www.uniprot.org/uniprotkb/Q5J3K1" } ], "pmid": "" } ], "biological_process": [ { "name": "response to pheromone", "id": "GO:0019236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019236", "evidence": [ { "database": "UniProtKB", "id": "Q5J3K1", "url": "https://www.uniprot.org/uniprotkb/Q5J3K1" } ], "pmid": "" }, { "name": "sensory perception of chemical stimulus", "id": "GO:0007606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007606", "evidence": [ { "database": "UniProtKB", "id": "Q5J3K1", "url": "https://www.uniprot.org/uniprotkb/Q5J3K1" } ], "pmid": "" } ], "molecular_function": [ { "name": "pheromone binding", "id": "GO:0005550", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005550", "evidence": [ { "database": "UniProtKB", "id": "Q5J3K1", "url": "https://www.uniprot.org/uniprotkb/Q5J3K1" } ], "pmid": "" }, { "name": "pheromone receptor activity", "id": "GO:0016503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016503", "evidence": [ { "database": "UniProtKB", "id": "Q5J3K1", "url": "https://www.uniprot.org/uniprotkb/Q5J3K1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q5J3K1-1", "start_pos": "92", "end_pos": "92", "site_lbl": "Thr92", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 92, "start_aa": "Thr", "end_pos": 92, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr92", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "Q5J3K1-1" }, { "uniprot_canonical_ac": "Q9QXF7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "Q9QXF7", "url": "https://www.uniprot.org/uniprotkb/Q9QXF7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 501, "chemical_mass": 57878.0, "gene_names": "CYP2J4", "protein_name": "Cytochrome P450 2J4", "disease": [], "biological_process": [ { "name": "positive regulation of extracellular matrix organization", "id": "GO:1903055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903055", "evidence": [ { "database": "UniProtKB", "id": "Q9QXF7", "url": "https://www.uniprot.org/uniprotkb/Q9QXF7" } ], "pmid": "" }, { "name": "icosanoid metabolic process", "id": "GO:0006690", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006690", "evidence": [ { "database": "UniProtKB", "id": "Q9QXF7", "url": "https://www.uniprot.org/uniprotkb/Q9QXF7" } ], "pmid": "" }, { "name": "retinoid metabolic process", "id": "GO:0001523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001523", "evidence": [ { "database": "UniProtKB", "id": "Q9QXF7", "url": "https://www.uniprot.org/uniprotkb/Q9QXF7" } ], "pmid": "" }, { "name": "linoleic acid metabolic process", "id": "GO:0043651", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043651", "evidence": [ { "database": "UniProtKB", "id": "Q9QXF7", "url": "https://www.uniprot.org/uniprotkb/Q9QXF7" } ], "pmid": "" }, { "name": "retinol metabolic process", "id": "GO:0042572", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042572", "evidence": [ { "database": "UniProtKB", "id": "Q9QXF7", "url": "https://www.uniprot.org/uniprotkb/Q9QXF7" } ], "pmid": "" }, { "name": "xenobiotic metabolic process", "id": "GO:0006805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006805", "evidence": [ { "database": "UniProtKB", "id": "Q9QXF7", "url": "https://www.uniprot.org/uniprotkb/Q9QXF7" } ], "pmid": "" }, { "name": "female pregnancy", "id": "GO:0007565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007565", "evidence": [ { "database": "UniProtKB", "id": "Q9QXF7", "url": "https://www.uniprot.org/uniprotkb/Q9QXF7" } ], "pmid": "" }, { "name": "positive regulation of tumor necrosis factor production", "id": "GO:0032760", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032760", "evidence": [ { "database": "UniProtKB", "id": "Q9QXF7", "url": "https://www.uniprot.org/uniprotkb/Q9QXF7" } ], "pmid": "" }, { "name": "negative regulation of peroxisome proliferator activated receptor signaling pathway", "id": "GO:0035359", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035359", "evidence": [ { "database": "UniProtKB", "id": "Q9QXF7", "url": "https://www.uniprot.org/uniprotkb/Q9QXF7" } ], "pmid": "" }, { "name": "positive regulation of gluconeogenesis", "id": "GO:0045722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045722", "evidence": [ { "database": "UniProtKB", "id": "Q9QXF7", "url": "https://www.uniprot.org/uniprotkb/Q9QXF7" } ], "pmid": "" }, { "name": "arachidonate metabolic process", "id": "GO:0019369", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019369", "evidence": [ { "database": "UniProtKB", "id": "Q9QXF7", "url": "https://www.uniprot.org/uniprotkb/Q9QXF7" } ], "pmid": "" }, { "name": "epoxygenase P450 pathway", "id": "GO:0019373", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019373", "evidence": [ { "database": "UniProtKB", "id": "Q9QXF7", "url": "https://www.uniprot.org/uniprotkb/Q9QXF7" } ], "pmid": "" }, { "name": "negative regulation of collagen biosynthetic process", "id": "GO:0032966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032966", "evidence": [ { "database": "UniProtKB", "id": "Q9QXF7", "url": "https://www.uniprot.org/uniprotkb/Q9QXF7" } ], "pmid": "" }, { "name": "organic acid metabolic process", "id": "GO:0006082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006082", "evidence": [ { "database": "UniProtKB", "id": "Q9QXF7", "url": "https://www.uniprot.org/uniprotkb/Q9QXF7" } ], "pmid": "" } ], "molecular_function": [ { "name": "arachidonate 14,15-epoxygenase activity", "id": "GO:0008404", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008404", "evidence": [ { "database": "UniProtKB", "id": "Q9QXF7", "url": "https://www.uniprot.org/uniprotkb/Q9QXF7" } ], "pmid": "" }, { "name": "arachidonate 11,12-epoxygenase activity", "id": "GO:0008405", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008405", "evidence": [ { "database": "UniProtKB", "id": "Q9QXF7", "url": "https://www.uniprot.org/uniprotkb/Q9QXF7" } ], "pmid": "" }, { "name": "linoleic acid epoxygenase activity", "id": "GO:0071614", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071614", "evidence": [ { "database": "UniProtKB", "id": "Q9QXF7", "url": "https://www.uniprot.org/uniprotkb/Q9QXF7" } ], "pmid": "" }, { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "Q9QXF7", "url": "https://www.uniprot.org/uniprotkb/Q9QXF7" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "Q9QXF7", "url": "https://www.uniprot.org/uniprotkb/Q9QXF7" } ], "pmid": "" }, { "name": "isomerase activity", "id": "GO:0016853", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016853", "evidence": [ { "database": "UniProtKB", "id": "Q9QXF7", "url": "https://www.uniprot.org/uniprotkb/Q9QXF7" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen", "id": "GO:0016712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016712", "evidence": [ { "database": "UniProtKB", "id": "Q9QXF7", "url": "https://www.uniprot.org/uniprotkb/Q9QXF7" } ], "pmid": "" }, { "name": "arachidonate epoxygenase activity", "id": "GO:0008392", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008392", "evidence": [ { "database": "UniProtKB", "id": "Q9QXF7", "url": "https://www.uniprot.org/uniprotkb/Q9QXF7" } ], "pmid": "" }, { "name": "NADPH-hemoprotein reductase activity", "id": "GO:0003958", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003958", "evidence": [ { "database": "UniProtKB", "id": "Q9QXF7", "url": "https://www.uniprot.org/uniprotkb/Q9QXF7" } ], "pmid": "" }, { "name": "arachidonate monooxygenase activity", "id": "GO:0008391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008391", "evidence": [ { "database": "UniProtKB", "id": "Q9QXF7", "url": "https://www.uniprot.org/uniprotkb/Q9QXF7" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9QXF7", "url": "https://www.uniprot.org/uniprotkb/Q9QXF7" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q9QXF7", "url": "https://www.uniprot.org/uniprotkb/Q9QXF7" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q9QXF7", "url": "https://www.uniprot.org/uniprotkb/Q9QXF7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9QXF7-1" }, { "uniprot_canonical_ac": "A0A7R8C3L7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A7R8C3L7", "url": "https://www.uniprot.org/uniprotkb/A0A7R8C3L7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 189, "chemical_mass": 21795.0, "gene_names": "Ifna1;If1ai3;Ifna1;Ifna5", "protein_name": "", "disease": [ { "disease_id": "DOID:12287", "name": "Crimean-Congo hemorrhagic fever", "description": "A viral infectious disease that is a hemorrhagic fever, has_material_basis_in Crimean-Congo haemorrhagic fever virus (Orthonairovirus haemorrhagiae), which is transmitted_by Hyalomma ticks. The infection has_symptom headache, has_symptom high fever, has_symptom back pain, has_symptom joint pain, has_symptom stomach pain, has_symptom vomiting, has_symptom red eyes, has_symptom flushed face, has_symptom red throat, has_symptom petechiae (red spots) on the palate, has_symptom jaundice, has_symptom nosebleeds, and has_symptom blood in the feces and urine.", "url": "https://disease-ontology.org/term/DOID:12287", "evidence": [ { "id": "12287", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12287" } ], "weight": 0.0 }, { "disease_id": "DOID:5052", "name": "melioidosis", "description": "A primary bacterial infectious disease that results_in infection, has_material_basis_in Burkholderia pseudomallei, which is transmitted_by contact with the contaminated water or soil. The infection has_symptom fever, has_symptom respiratory distress, has_symptom chest pain, and has_symptom stomach pain.", "url": "https://disease-ontology.org/term/DOID:5052", "evidence": [ { "id": "5052", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5052" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:8398", "name": "osteoarthritis", "description": "An arthritis that has_material_basis_in worn out cartilage located_in joint.", "url": "https://disease-ontology.org/term/DOID:8398", "evidence": [ { "id": "8398", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8398" } ], "weight": 0.0 } ], "biological_process": [ { "name": "regulation of defense response to virus by host", "id": "GO:0050691", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050691", "evidence": [ { "database": "UniProtKB", "id": "A0A7R8C3L7", "url": "https://www.uniprot.org/uniprotkb/A0A7R8C3L7" } ], "pmid": "" }, { "name": "B cell activation involved in immune response", "id": "GO:0002312", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002312", "evidence": [ { "database": "UniProtKB", "id": "A0A7R8C3L7", "url": "https://www.uniprot.org/uniprotkb/A0A7R8C3L7" } ], "pmid": "" }, { "name": "defense response to virus", "id": "GO:0051607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051607", "evidence": [ { "database": "UniProtKB", "id": "A0A7R8C3L7", "url": "https://www.uniprot.org/uniprotkb/A0A7R8C3L7" } ], "pmid": "" }, { "name": "type I interferon-mediated signaling pathway", "id": "GO:0060337", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060337", "evidence": [ { "database": "UniProtKB", "id": "A0A7R8C3L7", "url": "https://www.uniprot.org/uniprotkb/A0A7R8C3L7" } ], "pmid": "" }, { "name": "adaptive immune response", "id": "GO:0002250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002250", "evidence": [ { "database": "UniProtKB", "id": "A0A7R8C3L7", "url": "https://www.uniprot.org/uniprotkb/A0A7R8C3L7" } ], "pmid": "" }, { "name": "response to exogenous dsRNA", "id": "GO:0043330", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043330", "evidence": [ { "database": "UniProtKB", "id": "A0A7R8C3L7", "url": "https://www.uniprot.org/uniprotkb/A0A7R8C3L7" } ], "pmid": "" }, { "name": "defense response to bacterium", "id": "GO:0042742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042742", "evidence": [ { "database": "UniProtKB", "id": "A0A7R8C3L7", "url": "https://www.uniprot.org/uniprotkb/A0A7R8C3L7" } ], "pmid": "" }, { "name": "humoral immune response", "id": "GO:0006959", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006959", "evidence": [ { "database": "UniProtKB", "id": "A0A7R8C3L7", "url": "https://www.uniprot.org/uniprotkb/A0A7R8C3L7" } ], "pmid": "" }, { "name": "T cell activation involved in immune response", "id": "GO:0002286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002286", "evidence": [ { "database": "UniProtKB", "id": "A0A7R8C3L7", "url": "https://www.uniprot.org/uniprotkb/A0A7R8C3L7" } ], "pmid": "" }, { "name": "natural killer cell activation involved in immune response", "id": "GO:0002323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002323", "evidence": [ { "database": "UniProtKB", "id": "A0A7R8C3L7", "url": "https://www.uniprot.org/uniprotkb/A0A7R8C3L7" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A7R8C3L7", "url": "https://www.uniprot.org/uniprotkb/A0A7R8C3L7" } ], "pmid": "" } ], "molecular_function": [ { "name": "cytokine activity", "id": "GO:0005125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005125", "evidence": [ { "database": "UniProtKB", "id": "A0A7R8C3L7", "url": "https://www.uniprot.org/uniprotkb/A0A7R8C3L7" } ], "pmid": "" }, { "name": "type I interferon receptor binding", "id": "GO:0005132", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005132", "evidence": [ { "database": "UniProtKB", "id": "A0A7R8C3L7", "url": "https://www.uniprot.org/uniprotkb/A0A7R8C3L7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A7R8C3L7-1" }, { "uniprot_canonical_ac": "A0A8I5ZXV7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZXV7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZXV7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 320, "chemical_mass": 36073.0, "gene_names": "Or52z14;Olr112;Or52z14", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZXV7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZXV7" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZXV7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZXV7" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZXV7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZXV7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZXV7-1" }, { "uniprot_canonical_ac": "A0A8I6A6H9-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A6H9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A6H9" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 421, "chemical_mass": 46429.0, "gene_names": "Acot3;AC094055.1;Acot3;RGD1564089", "protein_name": "", "disease": [], "biological_process": [ { "name": "very long-chain fatty acid metabolic process", "id": "GO:0000038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000038", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A6H9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A6H9" } ], "pmid": "" }, { "name": "long-chain fatty acid metabolic process", "id": "GO:0001676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001676", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A6H9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A6H9" } ], "pmid": "" }, { "name": "fatty acid metabolic process", "id": "GO:0006631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006631", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A6H9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A6H9" } ], "pmid": "" }, { "name": "acyl-CoA metabolic process", "id": "GO:0006637", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006637", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A6H9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A6H9" } ], "pmid": "" }, { "name": "saturated monocarboxylic acid metabolic process", "id": "GO:0032788", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032788", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A6H9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A6H9" } ], "pmid": "" }, { "name": "unsaturated monocarboxylic acid metabolic process", "id": "GO:0032789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032789", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A6H9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A6H9" } ], "pmid": "" } ], "cellular_component": [ { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A6H9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A6H9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A6H9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A6H9" } ], "pmid": "" } ], "molecular_function": [ { "name": "fatty acyl-CoA hydrolase activity", "id": "GO:0047617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047617", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A6H9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A6H9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6A6H9-1" }, { "uniprot_canonical_ac": "A0A8I6AET5-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AET5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AET5" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 836, "chemical_mass": 94252.0, "gene_names": "Slitrk4;Slitrk4", "protein_name": "", "disease": [], "cellular_component": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AET5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AET5" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AET5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AET5" } ], "pmid": "" } ], "biological_process": [ { "name": "axonogenesis", "id": "GO:0007409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007409", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AET5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AET5" } ], "pmid": "" }, { "name": "memory", "id": "GO:0007613", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007613", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AET5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AET5" } ], "pmid": "" }, { "name": "cell population proliferation", "id": "GO:0008283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008283", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AET5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AET5" } ], "pmid": "" }, { "name": "positive regulation of synapse assembly", "id": "GO:0051965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051965", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AET5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AET5" } ], "pmid": "" }, { "name": "behavioral fear response", "id": "GO:0001662", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001662", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AET5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AET5" } ], "pmid": "" }, { "name": "smoothened signaling pathway", "id": "GO:0007224", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007224", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AET5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AET5" } ], "pmid": "" }, { "name": "long-term synaptic potentiation", "id": "GO:0060291", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060291", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AET5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AET5" } ], "pmid": "" }, { "name": "regulation of synapse organization", "id": "GO:0050807", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050807", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AET5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AET5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AET5-1" }, { "uniprot_canonical_ac": "F7F2Q6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F7F2Q6", "url": "https://www.uniprot.org/uniprotkb/F7F2Q6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 586, "chemical_mass": 63978.0, "gene_names": "Ythdf1", "protein_name": "YTH domain-containing family protein", "disease": [ { "disease_id": "DOID:0014667", "name": "disease of metabolism", "description": "A disease that involves errors in metabolic processes of building or degradation of molecules.", "url": "https://disease-ontology.org/term/DOID:0014667", "evidence": [ { "id": "0014667", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0014667" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 } ], "biological_process": [ { "name": "regulation of axon guidance", "id": "GO:1902667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902667", "evidence": [ { "database": "UniProtKB", "id": "F7F2Q6", "url": "https://www.uniprot.org/uniprotkb/F7F2Q6" } ], "pmid": "" }, { "name": "learning", "id": "GO:0007612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007612", "evidence": [ { "database": "UniProtKB", "id": "F7F2Q6", "url": "https://www.uniprot.org/uniprotkb/F7F2Q6" } ], "pmid": "" }, { "name": "memory", "id": "GO:0007613", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007613", "evidence": [ { "database": "UniProtKB", "id": "F7F2Q6", "url": "https://www.uniprot.org/uniprotkb/F7F2Q6" } ], "pmid": "" }, { "name": "regulation of mRNA stability", "id": "GO:0043488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043488", "evidence": [ { "database": "UniProtKB", "id": "F7F2Q6", "url": "https://www.uniprot.org/uniprotkb/F7F2Q6" } ], "pmid": "" }, { "name": "positive regulation of translation", "id": "GO:0045727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045727", "evidence": [ { "database": "UniProtKB", "id": "F7F2Q6", "url": "https://www.uniprot.org/uniprotkb/F7F2Q6" } ], "pmid": "" }, { "name": "regulation of long-term synaptic potentiation", "id": "GO:1900271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900271", "evidence": [ { "database": "UniProtKB", "id": "F7F2Q6", "url": "https://www.uniprot.org/uniprotkb/F7F2Q6" } ], "pmid": "" }, { "name": "stress granule assembly", "id": "GO:0034063", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034063", "evidence": [ { "database": "UniProtKB", "id": "F7F2Q6", "url": "https://www.uniprot.org/uniprotkb/F7F2Q6" } ], "pmid": "" }, { "name": "mRNA destabilization", "id": "GO:0061157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061157", "evidence": [ { "database": "UniProtKB", "id": "F7F2Q6", "url": "https://www.uniprot.org/uniprotkb/F7F2Q6" } ], "pmid": "" }, { "name": "positive regulation of translational initiation", "id": "GO:0045948", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045948", "evidence": [ { "database": "UniProtKB", "id": "F7F2Q6", "url": "https://www.uniprot.org/uniprotkb/F7F2Q6" } ], "pmid": "" }, { "name": "regulation of antigen processing and presentation", "id": "GO:0002577", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002577", "evidence": [ { "database": "UniProtKB", "id": "F7F2Q6", "url": "https://www.uniprot.org/uniprotkb/F7F2Q6" } ], "pmid": "" } ], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "F7F2Q6", "url": "https://www.uniprot.org/uniprotkb/F7F2Q6" } ], "pmid": "" }, { "name": "ribosome binding", "id": "GO:0043022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043022", "evidence": [ { "database": "UniProtKB", "id": "F7F2Q6", "url": "https://www.uniprot.org/uniprotkb/F7F2Q6" } ], "pmid": "" }, { "name": "N6-methyladenosine-containing RNA reader activity", "id": "GO:1990247", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990247", "evidence": [ { "database": "UniProtKB", "id": "F7F2Q6", "url": "https://www.uniprot.org/uniprotkb/F7F2Q6" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F7F2Q6", "url": "https://www.uniprot.org/uniprotkb/F7F2Q6" } ], "pmid": "" }, { "name": "P-body", "id": "GO:0000932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000932", "evidence": [ { "database": "UniProtKB", "id": "F7F2Q6", "url": "https://www.uniprot.org/uniprotkb/F7F2Q6" } ], "pmid": "" }, { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "F7F2Q6", "url": "https://www.uniprot.org/uniprotkb/F7F2Q6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F7F2Q6-1" }, { "uniprot_canonical_ac": "A0A8I6APD8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6APD8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6APD8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 239, "chemical_mass": 24147.0, "gene_names": "Krtap10-10l2;Krtap10-10l2;LOC690415", "protein_name": "", "disease": [], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6APD8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6APD8" } ], "pmid": "" }, { "name": "keratin filament", "id": "GO:0045095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045095", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6APD8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6APD8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6APD8-1", "start_pos": "61", "end_pos": "61", "site_lbl": "Thr61", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 61, "start_aa": "Thr", "end_pos": 61, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr61", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6APD8-1" }, { "uniprot_canonical_ac": "A0A8I6ASK8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ASK8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ASK8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 365, "chemical_mass": 38615.0, "gene_names": "Ankrd65;Ankrd65;RGD1562345", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6ASK8-1" }, { "uniprot_canonical_ac": "F7EKW8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F7EKW8", "url": "https://www.uniprot.org/uniprotkb/F7EKW8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 621, "chemical_mass": 66892.0, "gene_names": "Lrrc29;Lrrc29", "protein_name": "", "disease": [], "cellular_component": [ { "name": "SCF ubiquitin ligase complex", "id": "GO:0019005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019005", "evidence": [ { "database": "UniProtKB", "id": "F7EKW8", "url": "https://www.uniprot.org/uniprotkb/F7EKW8" } ], "pmid": "" } ], "biological_process": [ { "name": "SCF-dependent proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0031146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031146", "evidence": [ { "database": "UniProtKB", "id": "F7EKW8", "url": "https://www.uniprot.org/uniprotkb/F7EKW8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F7EKW8-1" }, { "uniprot_canonical_ac": "A0A8I6G3E9-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3E9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3E9" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 312, "chemical_mass": 35806.0, "gene_names": "Or4p19;Olr630;Or4p19", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3E9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3E9" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3E9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3E9" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3E9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3E9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6G3E9-1" }, { "uniprot_canonical_ac": "A0A8I6GHM2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GHM2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GHM2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 455, "chemical_mass": 51731.0, "gene_names": "Garin2", "protein_name": "", "disease": [], "cellular_component": [ { "name": "sperm head", "id": "GO:0061827", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061827", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GHM2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GHM2" } ], "pmid": "" }, { "name": "sperm midpiece", "id": "GO:0097225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097225", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GHM2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GHM2" } ], "pmid": "" } ], "biological_process": [ { "name": "flagellated sperm motility", "id": "GO:0030317", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030317", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GHM2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GHM2" } ], "pmid": "" }, { "name": "cell morphogenesis", "id": "GO:0000902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000902", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GHM2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GHM2" } ], "pmid": "" }, { "name": "spermatid development", "id": "GO:0007286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007286", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GHM2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GHM2" } ], "pmid": "" }, { "name": "penetration of zona pellucida", "id": "GO:0007341", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007341", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GHM2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GHM2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6GHM2-1", "start_pos": "72", "end_pos": "72", "site_lbl": "Thr72", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 72, "start_aa": "Thr", "end_pos": 72, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr72", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6GHM2-1" }, { "uniprot_canonical_ac": "A0A8I6GL80-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GL80", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GL80" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 184, "chemical_mass": 21013.0, "gene_names": "Mpv17l;Mpv17l", "protein_name": "", "disease": [ { "disease_id": "DOID:0080121", "name": "mitochondrial DNA depletion syndrome 3", "description": "A mitochondrial DNA depletion syndrome that is characterized by onset in infancy of progressive liver failure and neurologic abnormalities, hypoglycemia, and increased lactate in body fluids, and has_material_basis_in autosomal recessive inheritance of homozygous or compound heterozygous mutation in the deoxyguanosine kinase gene on chromosome 2p13.", "url": "https://disease-ontology.org/term/DOID:0080121", "evidence": [ { "id": "0080121", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080121" } ], "weight": 0.0 }, { "disease_id": "DOID:0080125", "name": "mitochondrial DNA depletion syndrome 6", "description": "A mitochondrial DNA depletion syndrome that is characterized by infantile onset of progressive liver failure, often leading to death in the first year of life, and has_material_basis_in autosomal recessive inheritance of homozygous or compound heterozygous mutation in the mitochondrial inner membrane protein MPV17 gene on chromosome 2p23.", "url": "https://disease-ontology.org/term/DOID:0080125", "evidence": [ { "id": "0080125", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080125" } ], "weight": 0.0 }, { "disease_id": "DOID:700", "name": "mitochondrial metabolism disease", "description": "An inherited metabolic disorder that involves mitochondrial metabolism dysfunction.", "url": "https://disease-ontology.org/term/DOID:700", "evidence": [ { "id": "700", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:700" } ], "weight": 0.0 } ], "biological_process": [ { "name": "negative regulation of hydrogen peroxide biosynthetic process", "id": "GO:0010730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010730", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GL80", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GL80" } ], "pmid": "" }, { "name": "negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "id": "GO:1901029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901029", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GL80", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GL80" } ], "pmid": "" }, { "name": "reactive oxygen species metabolic process", "id": "GO:0072593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072593", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GL80", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GL80" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GL80", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GL80" } ], "pmid": "" }, { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GL80", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GL80" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GL80", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GL80" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6GL80-1" }, { "uniprot_canonical_ac": "A1YKY5-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A1YKY5", "url": "https://www.uniprot.org/uniprotkb/A1YKY5" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 164, "chemical_mass": 18317.0, "gene_names": "Ucn3;RGD1562213;Ucn3", "protein_name": "", "disease": [], "molecular_function": [ { "name": "corticotropin-releasing hormone receptor binding", "id": "GO:0051429", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051429", "evidence": [ { "database": "UniProtKB", "id": "A1YKY5", "url": "https://www.uniprot.org/uniprotkb/A1YKY5" } ], "pmid": "" }, { "name": "hormone activity", "id": "GO:0005179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005179", "evidence": [ { "database": "UniProtKB", "id": "A1YKY5", "url": "https://www.uniprot.org/uniprotkb/A1YKY5" } ], "pmid": "" }, { "name": "corticotropin-releasing hormone receptor 2 binding", "id": "GO:0051431", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051431", "evidence": [ { "database": "UniProtKB", "id": "A1YKY5", "url": "https://www.uniprot.org/uniprotkb/A1YKY5" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A1YKY5", "url": "https://www.uniprot.org/uniprotkb/A1YKY5" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "A1YKY5", "url": "https://www.uniprot.org/uniprotkb/A1YKY5" } ], "pmid": "" }, { "name": "axon terminus", "id": "GO:0043679", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043679", "evidence": [ { "database": "UniProtKB", "id": "A1YKY5", "url": "https://www.uniprot.org/uniprotkb/A1YKY5" } ], "pmid": "" }, { "name": "varicosity", "id": "GO:0043196", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043196", "evidence": [ { "database": "UniProtKB", "id": "A1YKY5", "url": "https://www.uniprot.org/uniprotkb/A1YKY5" } ], "pmid": "" } ], "biological_process": [ { "name": "adenylate cyclase-activating G protein-coupled receptor signaling pathway", "id": "GO:0007189", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007189", "evidence": [ { "database": "UniProtKB", "id": "A1YKY5", "url": "https://www.uniprot.org/uniprotkb/A1YKY5" } ], "pmid": "" }, { "name": "positive regulation of insulin secretion", "id": "GO:0032024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032024", "evidence": [ { "database": "UniProtKB", "id": "A1YKY5", "url": "https://www.uniprot.org/uniprotkb/A1YKY5" } ], "pmid": "" }, { "name": "response to starvation", "id": "GO:0042594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042594", "evidence": [ { "database": "UniProtKB", "id": "A1YKY5", "url": "https://www.uniprot.org/uniprotkb/A1YKY5" } ], "pmid": "" }, { "name": "cellular response to hypoxia", "id": "GO:0071456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071456", "evidence": [ { "database": "UniProtKB", "id": "A1YKY5", "url": "https://www.uniprot.org/uniprotkb/A1YKY5" } ], "pmid": "" }, { "name": "hormone-mediated signaling pathway", "id": "GO:0009755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009755", "evidence": [ { "database": "UniProtKB", "id": "A1YKY5", "url": "https://www.uniprot.org/uniprotkb/A1YKY5" } ], "pmid": "" }, { "name": "digestion", "id": "GO:0007586", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007586", "evidence": [ { "database": "UniProtKB", "id": "A1YKY5", "url": "https://www.uniprot.org/uniprotkb/A1YKY5" } ], "pmid": "" }, { "name": "cellular response to nutrient levels", "id": "GO:0031669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031669", "evidence": [ { "database": "UniProtKB", "id": "A1YKY5", "url": "https://www.uniprot.org/uniprotkb/A1YKY5" } ], "pmid": "" }, { "name": "response to glucose", "id": "GO:0009749", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009749", "evidence": [ { "database": "UniProtKB", "id": "A1YKY5", "url": "https://www.uniprot.org/uniprotkb/A1YKY5" } ], "pmid": "" }, { "name": "response to corticosterone", "id": "GO:0051412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051412", "evidence": [ { "database": "UniProtKB", "id": "A1YKY5", "url": "https://www.uniprot.org/uniprotkb/A1YKY5" } ], "pmid": "" }, { "name": "positive regulation of membrane potential", "id": "GO:0045838", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045838", "evidence": [ { "database": "UniProtKB", "id": "A1YKY5", "url": "https://www.uniprot.org/uniprotkb/A1YKY5" } ], "pmid": "" }, { "name": "response to immobilization stress", "id": "GO:0035902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035902", "evidence": [ { "database": "UniProtKB", "id": "A1YKY5", "url": "https://www.uniprot.org/uniprotkb/A1YKY5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A1YKY5-1" }, { "uniprot_canonical_ac": "M0R7Q7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "M0R7Q7", "url": "https://www.uniprot.org/uniprotkb/M0R7Q7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 224, "chemical_mass": 25528.0, "gene_names": "LOC134481120", "protein_name": "Y-linked testis-specific protein 1-like", "disease": [], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "M0R7Q7", "url": "https://www.uniprot.org/uniprotkb/M0R7Q7" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "M0R7Q7", "url": "https://www.uniprot.org/uniprotkb/M0R7Q7" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "M0R7Q7", "url": "https://www.uniprot.org/uniprotkb/M0R7Q7" } ], "pmid": "" }, { "name": "gamete generation", "id": "GO:0007276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007276", "evidence": [ { "database": "UniProtKB", "id": "M0R7Q7", "url": "https://www.uniprot.org/uniprotkb/M0R7Q7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M0R7Q7-1" }, { "uniprot_canonical_ac": "M0R8L6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "M0R8L6", "url": "https://www.uniprot.org/uniprotkb/M0R8L6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 315, "chemical_mass": 35599.0, "gene_names": "Or13p5;Olr859;Or13p5", "protein_name": "", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "M0R8L6", "url": "https://www.uniprot.org/uniprotkb/M0R8L6" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "M0R8L6", "url": "https://www.uniprot.org/uniprotkb/M0R8L6" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "M0R8L6", "url": "https://www.uniprot.org/uniprotkb/M0R8L6" } ], "pmid": "" } ], "biological_process": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "M0R8L6", "url": "https://www.uniprot.org/uniprotkb/M0R8L6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M0R8L6-1" }, { "uniprot_canonical_ac": "Q6MFX5-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "Q6MFX5", "url": "https://www.uniprot.org/uniprotkb/Q6MFX5" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 312, "chemical_mass": 34839.0, "gene_names": "Or2h1b;Olr1748;Or2h1b;Or3", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "Q6MFX5", "url": "https://www.uniprot.org/uniprotkb/Q6MFX5" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "Q6MFX5", "url": "https://www.uniprot.org/uniprotkb/Q6MFX5" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q6MFX5", "url": "https://www.uniprot.org/uniprotkb/Q6MFX5" } ], "pmid": "" } ], "biological_process": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "Q6MFX5", "url": "https://www.uniprot.org/uniprotkb/Q6MFX5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q6MFX5-1" }, { "uniprot_canonical_ac": "Q6QI26-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "Q6QI26", "url": "https://www.uniprot.org/uniprotkb/Q6QI26" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 171, "chemical_mass": 19000.0, "gene_names": "", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q6QI26-1" }, { "uniprot_canonical_ac": "Q6ZMA1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "Q6ZMA1", "url": "https://www.uniprot.org/uniprotkb/Q6ZMA1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 309, "chemical_mass": 34107.0, "gene_names": "Or1o11;Olr1714;Or1o11;Or28;ratchr20-1103100-1102171_ORF", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "Q6ZMA1", "url": "https://www.uniprot.org/uniprotkb/Q6ZMA1" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "Q6ZMA1", "url": "https://www.uniprot.org/uniprotkb/Q6ZMA1" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q6ZMA1", "url": "https://www.uniprot.org/uniprotkb/Q6ZMA1" } ], "pmid": "" } ], "biological_process": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "Q6ZMA1", "url": "https://www.uniprot.org/uniprotkb/Q6ZMA1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q6ZMA1-1" }, { "uniprot_canonical_ac": "A0A0G2JW42-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JW42", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JW42" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 312, "chemical_mass": 35713.0, "gene_names": "Olr952;Olr952;ratchr7-4876211-4877149_ORF", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JW42", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JW42" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JW42", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JW42" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JW42", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JW42" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A0G2JW42-1" }, { "uniprot_canonical_ac": "A0A0G2K3J0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K3J0", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K3J0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 303, "chemical_mass": 32932.0, "gene_names": "Wbp1;Wbp1", "protein_name": "", "disease": [], "molecular_function": [ { "name": "WW domain binding", "id": "GO:0050699", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050699", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K3J0", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K3J0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A0G2K3J0-1" }, { "uniprot_canonical_ac": "A0A8I5XV08-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XV08", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XV08" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 309, "chemical_mass": 32128.0, "gene_names": "ENSRNOG00000067173", "protein_name": "NHL-repeat-containing protein 4", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I5XV08-1", "start_pos": "130", "end_pos": "130", "site_lbl": "Thr130", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 130, "start_aa": "Thr", "end_pos": 130, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr130", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I5XV08-1" }, { "uniprot_canonical_ac": "A0A8I5XW99-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XW99", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XW99" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 311, "chemical_mass": 34979.0, "gene_names": "Or8g37b;Olr1327;Or8g37b", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XW99", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XW99" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XW99", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XW99" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XW99", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XW99" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XW99", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XW99" } ], "pmid": "" } ], "biological_process": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XW99", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XW99" } ], "pmid": "" }, { "name": "sensory perception of smell", "id": "GO:0007608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007608", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XW99", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XW99" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5XW99-1" }, { "uniprot_canonical_ac": "A0A8I5Y7T3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y7T3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y7T3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 312, "chemical_mass": 35460.0, "gene_names": "Or5aq7;Olr542;Or5aq7", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y7T3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y7T3" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y7T3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y7T3" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y7T3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y7T3" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y7T3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y7T3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5Y7T3-1" }, { "uniprot_canonical_ac": "A0A8I5YC63-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YC63", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YC63" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 140, "chemical_mass": 13515.0, "gene_names": "LOC108351864;LOC120100586", "protein_name": "", "disease": [], "biological_process": [ { "name": "keratinization", "id": "GO:0031424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031424", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YC63", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YC63" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5YC63-1" }, { "uniprot_canonical_ac": "A0A8I5ZMC7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMC7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMC7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 262, "chemical_mass": 28381.0, "gene_names": "Prr23a3;Prr23a2;Prr23a3", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZMC7-1" }, { "uniprot_canonical_ac": "A0A8I5ZNS9-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNS9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNS9" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 308, "chemical_mass": 34928.0, "gene_names": "Or4p8;Olr661;Or4p8", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNS9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNS9" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNS9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNS9" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNS9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNS9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZNS9-1" }, { "uniprot_canonical_ac": "A0A8I5ZPS4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZPS4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZPS4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 573, "chemical_mass": 63637.0, "gene_names": "Zfp956;RGD1304879;Zfp956;Zfp977", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZPS4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZPS4" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZPS4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZPS4" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZPS4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZPS4" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZPS4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZPS4" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZPS4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZPS4" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZPS4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZPS4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZPS4-1" }, { "uniprot_canonical_ac": "A0A8I5ZPT2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZPT2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZPT2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 154, "chemical_mass": 17510.0, "gene_names": "ENSRNOG00000064673;Gm21834", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZPT2-1" }, { "uniprot_canonical_ac": "A0A8I5ZRD8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZRD8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZRD8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 307, "chemical_mass": 34563.0, "gene_names": "Or8g2c;Olr1325;Or8g2c", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZRD8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZRD8" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZRD8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZRD8" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZRD8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZRD8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZRD8-1" }, { "uniprot_canonical_ac": "A0A8I5ZUC8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUC8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUC8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 306, "chemical_mass": 33858.0, "gene_names": "Ldlrad4;Ldlrad4", "protein_name": "", "disease": [], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUC8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUC8" } ], "pmid": "" }, { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUC8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUC8" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of cell migration", "id": "GO:0030336", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030336", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUC8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUC8" } ], "pmid": "" }, { "name": "negative regulation of transforming growth factor beta receptor signaling pathway", "id": "GO:0030512", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030512", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUC8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUC8" } ], "pmid": "" }, { "name": "negative regulation of epithelial to mesenchymal transition", "id": "GO:0010719", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010719", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUC8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUC8" } ], "pmid": "" }, { "name": "negative regulation of SMAD protein signal transduction", "id": "GO:0060392", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060392", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUC8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUC8" } ], "pmid": "" } ], "molecular_function": [ { "name": "R-SMAD binding", "id": "GO:0070412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070412", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUC8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUC8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZUC8-1" }, { "uniprot_canonical_ac": "A0A8I5ZUY5-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUY5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUY5" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 315, "chemical_mass": 35643.0, "gene_names": "Or9i2;Olr383;Or9i2", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUY5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUY5" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUY5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUY5" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUY5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUY5" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUY5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUY5" } ], "pmid": "" } ], "biological_process": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUY5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUY5" } ], "pmid": "" }, { "name": "sensory perception of smell", "id": "GO:0007608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007608", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUY5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUY5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZUY5-1" }, { "uniprot_canonical_ac": "A0A8I5ZV13-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZV13", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZV13" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 705, "chemical_mass": 79598.0, "gene_names": "Mettl13;Eef1aknmt;Mettl13;RGD1311526", "protein_name": "eEF1A lysine and N-terminal methyltransferase", "disease": [ { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZV13", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZV13" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZV13", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZV13" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZV13", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZV13" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZV13", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZV13" } ], "pmid": "" } ], "biological_process": [ { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZV13", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZV13" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-lysine N-methyltransferase activity", "id": "GO:0016279", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016279", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZV13", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZV13" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZV13-1" }, { "uniprot_canonical_ac": "A0A8I5ZWX3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZWX3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZWX3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 604, "chemical_mass": 67913.0, "gene_names": "Mapda;Adal", "protein_name": "", "disease": [], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZWX3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZWX3" } ], "pmid": "" }, { "name": "structural molecule activity", "id": "GO:0005198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005198", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZWX3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZWX3" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZWX3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZWX3" } ], "pmid": "" }, { "name": "N6-methyl-AMP deaminase activity", "id": "GO:0062154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0062154", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZWX3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZWX3" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZWX3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZWX3" } ], "pmid": "" }, { "name": "deaminase activity", "id": "GO:0019239", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019239", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZWX3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZWX3" } ], "pmid": "" } ], "biological_process": [ { "name": "viral process", "id": "GO:0016032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016032", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZWX3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZWX3" } ], "pmid": "" }, { "name": "toxic metabolite repair", "id": "GO:0110052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0110052", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZWX3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZWX3" } ], "pmid": "" }, { "name": "nucleotide metabolic process", "id": "GO:0009117", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009117", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZWX3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZWX3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZWX3-1" }, { "uniprot_canonical_ac": "A0A8I5ZWY2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZWY2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZWY2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 307, "chemical_mass": 34498.0, "gene_names": "Or1ad1;Olr1405;Or1ad1", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZWY2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZWY2" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZWY2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZWY2" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZWY2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZWY2" } ], "pmid": "" } ], "biological_process": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZWY2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZWY2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZWY2-1" }, { "uniprot_canonical_ac": "A0A8I5ZWY4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZWY4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZWY4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 256, "chemical_mass": 28449.0, "gene_names": "Ado;Ado;RGD1308233", "protein_name": "", "disease": [], "molecular_function": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZWY4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZWY4" } ], "pmid": "" }, { "name": "cysteamine dioxygenase activity", "id": "GO:0047800", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047800", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZWY4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZWY4" } ], "pmid": "" } ], "biological_process": [ { "name": "cellular response to hypoxia", "id": "GO:0071456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071456", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZWY4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZWY4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZWY4-1" }, { "uniprot_canonical_ac": "A0A8I5ZX92-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZX92", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZX92" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 330, "chemical_mass": 37227.0, "gene_names": "Or12k5;Olr421;Or12k5;Or12k7", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZX92", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZX92" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZX92", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZX92" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZX92", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZX92" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZX92-1" }, { "uniprot_canonical_ac": "A0A8I5ZY03-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZY03", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZY03" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 186, "chemical_mass": 20876.0, "gene_names": "Tnfaip8l1;Tnfaip8l1", "protein_name": "Tumor necrosis factor alpha-induced protein 8-like protein 1", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZY03", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZY03" } ], "pmid": "" } ], "molecular_function": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZY03", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZY03" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of TOR signaling", "id": "GO:0032007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032007", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZY03", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZY03" } ], "pmid": "" }, { "name": "regulation of apoptotic process", "id": "GO:0042981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042981", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZY03", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZY03" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZY03-1" }, { "uniprot_canonical_ac": "A0A8I5ZY13-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZY13", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZY13" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 788, "chemical_mass": 91574.0, "gene_names": "Ppp4r3cl2;Ppp4r3cl2;RGD1563978", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZY13", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZY13" } ], "pmid": "" }, { "name": "protein phosphatase 4 complex", "id": "GO:0030289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030289", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZY13", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZY13" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZY13", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZY13" } ], "pmid": "" }, { "name": "regulation of double-strand break repair", "id": "GO:2000779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000779", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZY13", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZY13" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein phosphatase activator activity", "id": "GO:0072542", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072542", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZY13", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZY13" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZY13-1" }, { "uniprot_canonical_ac": "A0A8I5ZYM7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYM7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYM7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 186, "chemical_mass": 19869.0, "gene_names": "AABR07002627.1", "protein_name": "VTT domain-containing protein", "disease": [], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYM7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYM7" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of cytosolic calcium ion concentration", "id": "GO:0051480", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051480", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYM7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYM7" } ], "pmid": "" }, { "name": "positive regulation of bone resorption", "id": "GO:0045780", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045780", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYM7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYM7" } ], "pmid": "" }, { "name": "positive regulation of osteoclast differentiation", "id": "GO:0045672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045672", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYM7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYM7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZYM7-1" }, { "uniprot_canonical_ac": "A0A8I5ZYQ8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYQ8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 317, "chemical_mass": 36575.0, "gene_names": "ENSRNOG00000067336;C1galt1c1-ps1", "protein_name": "C1GALT1-specific chaperone 1", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYQ8" } ], "pmid": "" } ], "biological_process": [ { "name": "protein O-linked glycosylation", "id": "GO:0006493", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006493", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYQ8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZYQ8-1" }, { "uniprot_canonical_ac": "A0A8I6A305-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A305", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A305" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 892, "chemical_mass": 102176.0, "gene_names": "Dpp8;Dpp8", "protein_name": "dipeptidyl-peptidase IV", "disease": [], "molecular_function": [ { "name": "dipeptidyl-peptidase activity", "id": "GO:0008239", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008239", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A305", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A305" } ], "pmid": "" }, { "name": "aminopeptidase activity", "id": "GO:0004177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004177", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A305", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A305" } ], "pmid": "" }, { "name": "serine-type peptidase activity", "id": "GO:0008236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008236", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A305", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A305" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A305", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A305" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A305", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A305" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A305", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A305" } ], "pmid": "" }, { "name": "negative regulation of programmed cell death", "id": "GO:0043069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043069", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A305", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A305" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6A305-1" }, { "uniprot_canonical_ac": "A0A8I6A438-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A438", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A438" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 151, "chemical_mass": 17227.0, "gene_names": "Gtsf1l;Gtsf1l;RGD1306224", "protein_name": "", "disease": [], "molecular_function": [ { "name": "protein-containing complex binding", "id": "GO:0044877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044877", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A438", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A438" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6A438-1" }, { "uniprot_canonical_ac": "A0A8I6A7D3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A7D3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A7D3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 292, "chemical_mass": 33280.0, "gene_names": "Kctd12b;Kctd12b", "protein_name": "", "disease": [], "cellular_component": [ { "name": "GABA-ergic synapse", "id": "GO:0098982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098982", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A7D3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A7D3" } ], "pmid": "" }, { "name": "presynaptic active zone membrane", "id": "GO:0048787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048787", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A7D3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A7D3" } ], "pmid": "" }, { "name": "receptor complex", "id": "GO:0043235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043235", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A7D3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A7D3" } ], "pmid": "" }, { "name": "postsynaptic membrane", "id": "GO:0045211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045211", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A7D3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A7D3" } ], "pmid": "" }, { "name": "presynaptic membrane", "id": "GO:0042734", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042734", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A7D3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A7D3" } ], "pmid": "" } ], "biological_process": [ { "name": "protein homooligomerization", "id": "GO:0051260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051260", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A7D3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A7D3" } ], "pmid": "" }, { "name": "regulation of G protein-coupled receptor signaling pathway", "id": "GO:0008277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008277", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A7D3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A7D3" } ], "pmid": "" } ], "molecular_function": [ { "name": "G protein-coupled neurotransmitter receptor activity involved in regulation of presynaptic membrane potential", "id": "GO:0150047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0150047", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A7D3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A7D3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6A7D3-1" }, { "uniprot_canonical_ac": "A0A8I6A7T2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A7T2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A7T2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 317, "chemical_mass": 34795.0, "gene_names": "Or2g25;Olr1702;Or2g25", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A7T2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A7T2" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A7T2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A7T2" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A7T2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A7T2" } ], "pmid": "" } ], "biological_process": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A7T2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A7T2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6A7T2-1" }, { "uniprot_canonical_ac": "A0A8I6A837-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A837", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A837" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 315, "chemical_mass": 35611.0, "gene_names": "Or2v2;Olr1385;Or2v2b;Or2v2;ratchr10-34281870-34280923_ORF", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A837", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A837" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A837", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A837" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A837", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A837" } ], "pmid": "" } ], "biological_process": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A837", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A837" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6A837-1" }, { "uniprot_canonical_ac": "A0A8I6A9J8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A9J8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A9J8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 174, "chemical_mass": 18342.0, "gene_names": "Krtap13-2;Krtap13-2;RGD1559597", "protein_name": "Keratin-associated protein", "disease": [], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A9J8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A9J8" } ], "pmid": "" }, { "name": "keratin filament", "id": "GO:0045095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045095", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A9J8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A9J8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6A9J8-1" }, { "uniprot_canonical_ac": "A0A8I6A9Z0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A9Z0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A9Z0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 204, "chemical_mass": 22553.0, "gene_names": "Ms4a20", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6A9Z0-1" }, { "uniprot_canonical_ac": "A0A8I6AAI7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AAI7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AAI7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 314, "chemical_mass": 35079.0, "gene_names": "Or4a77c;Olr713;Or4a77c", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AAI7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AAI7" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AAI7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AAI7" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AAI7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AAI7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AAI7-1" }, { "uniprot_canonical_ac": "A0A8I6AAW1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AAW1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AAW1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 790, "chemical_mass": 91215.0, "gene_names": "Tars3;RGD1311308;Tars3;Tarsl2", "protein_name": "threonine--tRNA ligase", "disease": [ { "disease_id": "DOID:0111867", "name": "nonphotosensitive trichothiodystrophy", "description": "A trichothiodystrophy characterized by absence of extreme sensitivity to UV radiation.", "url": "https://disease-ontology.org/term/DOID:0111867", "evidence": [ { "id": "0111867", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111867" } ], "weight": 0.0 }, { "disease_id": "DOID:9252", "name": "amino acid metabolic disorder", "description": "An inherited metabolic disorder that is characterized by impaired synthesis and degradation of amino acids.", "url": "https://disease-ontology.org/term/DOID:9252", "evidence": [ { "id": "9252", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9252" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AAW1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AAW1" } ], "pmid": "" }, { "name": "threonine-tRNA ligase activity", "id": "GO:0004829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AAW1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AAW1" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AAW1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AAW1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AAW1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AAW1" } ], "pmid": "" } ], "biological_process": [ { "name": "threonyl-tRNA aminoacylation", "id": "GO:0006435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006435", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AAW1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AAW1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AAW1-1" }, { "uniprot_canonical_ac": "A0A8I6AB26-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AB26", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AB26" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 284, "chemical_mass": 30371.0, "gene_names": "Tmem200b;Tmem200b", "protein_name": "", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AB26", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AB26" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AB26-1" }, { "uniprot_canonical_ac": "A0A8I6ABG7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABG7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABG7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 312, "chemical_mass": 35279.0, "gene_names": "Or4f7b;Olr774;Or4f7b", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABG7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABG7" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABG7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABG7" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABG7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABG7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6ABG7-1" }, { "uniprot_canonical_ac": "A0A8I6ACD0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACD0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACD0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 983, "chemical_mass": 109666.0, "gene_names": "Zbed6;Zbed6", "protein_name": "", "disease": [], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACD0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACD0" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACD0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACD0" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACD0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACD0" } ], "pmid": "" }, { "name": "regulation of insulin secretion involved in cellular response to glucose stimulus", "id": "GO:0061178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061178", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACD0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACD0" } ], "pmid": "" }, { "name": "blastocyst hatching", "id": "GO:0001835", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001835", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACD0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACD0" } ], "pmid": "" }, { "name": "negative regulation of muscle cell differentiation", "id": "GO:0051148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051148", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACD0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACD0" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACD0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACD0" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACD0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACD0" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACD0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACD0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACD0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACD0" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACD0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACD0" } ], "pmid": "" }, { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACD0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACD0" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACD0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACD0" } ], "pmid": "" }, { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACD0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACD0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6ACD0-1" }, { "uniprot_canonical_ac": "A0A8I6ACQ4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACQ4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 308, "chemical_mass": 34360.0, "gene_names": "Or13n4;Olr211;Or13n4;ratchr1-164083610-164082684_ORF", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACQ4" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACQ4" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACQ4" } ], "pmid": "" } ], "biological_process": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACQ4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6ACQ4-1" }, { "uniprot_canonical_ac": "A0A8I6ACV5-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACV5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACV5" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 323, "chemical_mass": 35982.0, "gene_names": "Or14j15;Olr1691;Or14j5b", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACV5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACV5" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACV5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACV5" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACV5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACV5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6ACV5-1" }, { "uniprot_canonical_ac": "A0A8I6ADB2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ADB2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ADB2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 843, "chemical_mass": 97473.0, "gene_names": "LOC120102832;LOC120102832", "protein_name": "", "disease": [], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ADB2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ADB2" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ADB2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ADB2" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ADB2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ADB2" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of RNA splicing", "id": "GO:0043484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043484", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ADB2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ADB2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6ADB2-1" }, { "uniprot_canonical_ac": "A0A8I6AFN4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AFN4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AFN4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 467, "chemical_mass": 52627.0, "gene_names": "Zbtb43;Zbtb43;Zfp297b", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AFN4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AFN4" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AFN4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AFN4" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AFN4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AFN4" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AFN4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AFN4" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AFN4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AFN4" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AFN4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AFN4" } ], "pmid": "" }, { "name": "RNA polymerase III general transcription initiation factor binding", "id": "GO:0001025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001025", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AFN4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AFN4" } ], "pmid": "" }, { "name": "sequence-specific double-stranded DNA binding", "id": "GO:1990837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990837", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AFN4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AFN4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AFN4-1" }, { "uniprot_canonical_ac": "Q6ZXC8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "Q6ZXC8", "url": "https://www.uniprot.org/uniprotkb/Q6ZXC8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 376, "chemical_mass": 43840.0, "gene_names": "St8sia5;SATV;SIAT8-E;SIAT8E;ST8SiaV;Siat8e;St8sia5;St8siav", "protein_name": "Alpha-2,8-sialyltransferase 8E", "disease": [], "molecular_function": [ { "name": "alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity", "id": "GO:0003828", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003828", "evidence": [ { "database": "UniProtKB", "id": "Q6ZXC8", "url": "https://www.uniprot.org/uniprotkb/Q6ZXC8" } ], "pmid": "" }, { "name": "sialyltransferase activity", "id": "GO:0008373", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008373", "evidence": [ { "database": "UniProtKB", "id": "Q6ZXC8", "url": "https://www.uniprot.org/uniprotkb/Q6ZXC8" } ], "pmid": "" } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "Q6ZXC8", "url": "https://www.uniprot.org/uniprotkb/Q6ZXC8" } ], "pmid": "" } ], "biological_process": [ { "name": "glycosphingolipid biosynthetic process", "id": "GO:0006688", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006688", "evidence": [ { "database": "UniProtKB", "id": "Q6ZXC8", "url": "https://www.uniprot.org/uniprotkb/Q6ZXC8" } ], "pmid": "" }, { "name": "oligosaccharide metabolic process", "id": "GO:0009311", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009311", "evidence": [ { "database": "UniProtKB", "id": "Q6ZXC8", "url": "https://www.uniprot.org/uniprotkb/Q6ZXC8" } ], "pmid": "" }, { "name": "N-glycan processing", "id": "GO:0006491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006491", "evidence": [ { "database": "UniProtKB", "id": "Q6ZXC8", "url": "https://www.uniprot.org/uniprotkb/Q6ZXC8" } ], "pmid": "" }, { "name": "glycoprotein biosynthetic process", "id": "GO:0009101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009101", "evidence": [ { "database": "UniProtKB", "id": "Q6ZXC8", "url": "https://www.uniprot.org/uniprotkb/Q6ZXC8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6ZXC8-1", "start_pos": "241", "end_pos": "241", "site_lbl": "Asn241", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 241, "start_aa": "Asn", "end_pos": 241, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn241", "evidence": [ { "id": "Q6ZXC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6ZXC8#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q6ZXC8-1", "start_pos": "56", "end_pos": "56", "site_lbl": "Asn56", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 56, "start_aa": "Asn", "end_pos": 56, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn56", "evidence": [ { "id": "Q6ZXC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6ZXC8#ptm_processing" } ] } ] } ], "record_id": "Q6ZXC8-1" }, { "uniprot_canonical_ac": "C0HLM6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "C0HLM6", "url": "https://www.uniprot.org/uniprotkb/C0HLM6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 69, "chemical_mass": 7800.0, "gene_names": "Smim20;AABR07015507.1;MITRAC7;PNX;RGD1565192;Smim20", "protein_name": "Small integral membrane protein 20", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "C0HLM6", "url": "https://www.uniprot.org/uniprotkb/C0HLM6" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "C0HLM6", "url": "https://www.uniprot.org/uniprotkb/C0HLM6" } ], "pmid": "" } ], "biological_process": [ { "name": "mitochondrial respiratory chain complex IV assembly", "id": "GO:0033617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033617", "evidence": [ { "database": "UniProtKB", "id": "C0HLM6", "url": "https://www.uniprot.org/uniprotkb/C0HLM6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "C0HLM6-1" }, { "uniprot_canonical_ac": "A0A8I6ADK8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ADK8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ADK8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1614, "chemical_mass": 180847.0, "gene_names": "Rapgef6;Rapgef6", "protein_name": "", "disease": [], "biological_process": [ { "name": "Rap protein signal transduction", "id": "GO:0032486", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032486", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ADK8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ADK8" } ], "pmid": "" }, { "name": "neuron projection development", "id": "GO:0031175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031175", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ADK8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ADK8" } ], "pmid": "" }, { "name": "Ras protein signal transduction", "id": "GO:0007265", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007265", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ADK8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ADK8" } ], "pmid": "" }, { "name": "positive regulation of microvillus assembly", "id": "GO:1903698", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903698", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ADK8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ADK8" } ], "pmid": "" }, { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ADK8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ADK8" } ], "pmid": "" }, { "name": "positive regulation of intracellular signal transduction", "id": "GO:1902533", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902533", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ADK8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ADK8" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ADK8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ADK8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ADK8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ADK8" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ADK8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ADK8" } ], "pmid": "" }, { "name": "endocytic vesicle", "id": "GO:0030139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030139", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ADK8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ADK8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ADK8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ADK8" } ], "pmid": "" } ], "molecular_function": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ADK8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ADK8" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ADK8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ADK8" } ], "pmid": "" }, { "name": "GTP-dependent protein binding", "id": "GO:0030742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030742", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ADK8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ADK8" } ], "pmid": "" }, { "name": "phosphatidic acid binding", "id": "GO:0070300", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070300", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ADK8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ADK8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6ADK8-1", "start_pos": "1519", "end_pos": "1519", "site_lbl": "Thr1519", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1519, "start_aa": "Thr", "end_pos": 1519, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1519", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6ADK8-1" }, { "uniprot_canonical_ac": "A0A8I5ZWS4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZWS4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZWS4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 725, "chemical_mass": 83946.0, "gene_names": "Hook3;AABR07026291.1", "protein_name": "Protein Hook homolog 3", "disease": [ { "disease_id": "DOID:11726", "name": "Emery-Dreifuss muscular dystrophy", "description": "A muscular dystrophy that chiefly affects muscles used for movement (skeletal) and heart (cardiac) muscle.", "url": "https://disease-ontology.org/term/DOID:11726", "evidence": [ { "id": "11726", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11726" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZWS4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZWS4" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZWS4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZWS4" } ], "pmid": "" }, { "name": "dynactin binding", "id": "GO:0034452", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034452", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZWS4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZWS4" } ], "pmid": "" }, { "name": "dynein light intermediate chain binding", "id": "GO:0051959", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051959", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZWS4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZWS4" } ], "pmid": "" }, { "name": "dynein light chain binding", "id": "GO:0045503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045503", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZWS4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZWS4" } ], "pmid": "" }, { "name": "dynein intermediate chain binding", "id": "GO:0045505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045505", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZWS4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZWS4" } ], "pmid": "" } ], "biological_process": [ { "name": "cytoplasmic microtubule organization", "id": "GO:0031122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031122", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZWS4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZWS4" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZWS4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZWS4" } ], "pmid": "" }, { "name": "endosome organization", "id": "GO:0007032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007032", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZWS4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZWS4" } ], "pmid": "" }, { "name": "lysosome organization", "id": "GO:0007040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007040", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZWS4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZWS4" } ], "pmid": "" }, { "name": "endosome to lysosome transport", "id": "GO:0008333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008333", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZWS4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZWS4" } ], "pmid": "" }, { "name": "early endosome to late endosome transport", "id": "GO:0045022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045022", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZWS4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZWS4" } ], "pmid": "" }, { "name": "negative regulation of neurogenesis", "id": "GO:0050768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050768", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZWS4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZWS4" } ], "pmid": "" }, { "name": "cytoskeleton-dependent intracellular transport", "id": "GO:0030705", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030705", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZWS4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZWS4" } ], "pmid": "" }, { "name": "protein localization to perinuclear region of cytoplasm", "id": "GO:1905719", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905719", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZWS4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZWS4" } ], "pmid": "" }, { "name": "protein localization to centrosome", "id": "GO:0071539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071539", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZWS4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZWS4" } ], "pmid": "" }, { "name": "Golgi localization", "id": "GO:0051645", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051645", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZWS4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZWS4" } ], "pmid": "" }, { "name": "interkinetic nuclear migration", "id": "GO:0022027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022027", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZWS4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZWS4" } ], "pmid": "" }, { "name": "neuronal stem cell population maintenance", "id": "GO:0097150", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097150", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZWS4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZWS4" } ], "pmid": "" }, { "name": "microtubule anchoring at centrosome", "id": "GO:0034454", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034454", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZWS4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZWS4" } ], "pmid": "" } ], "cellular_component": [ { "name": "HOPS complex", "id": "GO:0030897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030897", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZWS4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZWS4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZWS4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZWS4" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZWS4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZWS4" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZWS4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZWS4" } ], "pmid": "" }, { "name": "FHF complex", "id": "GO:0070695", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070695", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZWS4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZWS4" } ], "pmid": "" }, { "name": "cis-Golgi network", "id": "GO:0005801", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005801", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZWS4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZWS4" } ], "pmid": "" }, { "name": "centriolar satellite", "id": "GO:0034451", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034451", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZWS4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZWS4" } ], "pmid": "" }, { "name": "pericentriolar material", "id": "GO:0000242", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000242", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZWS4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZWS4" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZWS4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZWS4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZWS4-1" }, { "uniprot_canonical_ac": "A0A8I6A4H4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A4H4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A4H4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1777, "chemical_mass": 196447.0, "gene_names": "N4bp2", "protein_name": "NEDD4-binding protein 2-like 2", "disease": [], "molecular_function": [ { "name": "ubiquitin binding", "id": "GO:0043130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043130", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A4H4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A4H4" } ], "pmid": "" }, { "name": "ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity", "id": "GO:0046404", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046404", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A4H4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A4H4" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A4H4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A4H4" } ], "pmid": "" }, { "name": "endonuclease activity", "id": "GO:0004519", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004519", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A4H4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A4H4" } ], "pmid": "" }, { "name": "DNA endonuclease activity", "id": "GO:0004520", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004520", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A4H4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A4H4" } ], "pmid": "" } ], "biological_process": [ { "name": "nuclear-transcribed mRNA catabolic process, non-stop decay", "id": "GO:0070481", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070481", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A4H4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A4H4" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A4H4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A4H4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6A4H4-1" }, { "uniprot_canonical_ac": "A0A8I6A2K3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2K3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2K3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 177, "chemical_mass": 20406.0, "gene_names": "Prelid2;Prelid2", "protein_name": "", "disease": [], "cellular_component": [ { "name": "mitochondrial intermembrane space", "id": "GO:0005758", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005758", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2K3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2K3" } ], "pmid": "" } ], "molecular_function": [ { "name": "phosphatidic acid transfer activity", "id": "GO:1990050", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990050", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2K3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2K3" } ], "pmid": "" } ], "biological_process": [ { "name": "phospholipid transport", "id": "GO:0015914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015914", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2K3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2K3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6A2K3-1" }, { "uniprot_canonical_ac": "A0A8I6A8W0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A8W0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A8W0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 557, "chemical_mass": 63358.0, "gene_names": "Rab11fip2", "protein_name": "Rab11 family-interacting protein 2", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A8W0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A8W0" } ], "pmid": "" }, { "name": "recycling endosome membrane", "id": "GO:0055038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055038", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A8W0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A8W0" } ], "pmid": "" }, { "name": "phagocytic cup", "id": "GO:0001891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001891", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A8W0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A8W0" } ], "pmid": "" }, { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A8W0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A8W0" } ], "pmid": "" } ], "biological_process": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A8W0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A8W0" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A8W0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A8W0" } ], "pmid": "" }, { "name": "cell communication", "id": "GO:0007154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007154", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A8W0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A8W0" } ], "pmid": "" }, { "name": "signaling", "id": "GO:0023052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0023052", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A8W0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A8W0" } ], "pmid": "" }, { "name": "TRAM-dependent toll-like receptor 4 signaling pathway", "id": "GO:0035669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035669", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A8W0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A8W0" } ], "pmid": "" }, { "name": "positive regulation of GTPase activity", "id": "GO:0043547", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043547", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A8W0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A8W0" } ], "pmid": "" }, { "name": "regulated exocytosis", "id": "GO:0045055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045055", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A8W0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A8W0" } ], "pmid": "" }, { "name": "phagocytosis", "id": "GO:0006909", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006909", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A8W0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A8W0" } ], "pmid": "" }, { "name": "positive regulation of protein localization to plasma membrane", "id": "GO:1903078", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903078", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A8W0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A8W0" } ], "pmid": "" }, { "name": "establishment of cell polarity", "id": "GO:0030010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030010", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A8W0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A8W0" } ], "pmid": "" }, { "name": "insulin secretion involved in cellular response to glucose stimulus", "id": "GO:0035773", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035773", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A8W0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A8W0" } ], "pmid": "" } ], "molecular_function": [ { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A8W0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A8W0" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A8W0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A8W0" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A8W0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A8W0" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A8W0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A8W0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6A8W0-1" }, { "uniprot_canonical_ac": "A0A8I6A5F2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5F2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5F2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 944, "chemical_mass": 105879.0, "gene_names": "Get4;Sun1;Sun1;Unc84a", "protein_name": "", "disease": [ { "disease_id": "DOID:0051052", "name": "congenital disorder of glycosylation type IIy", "description": "A congenital disorder of glycosylation type II that is characterized by poor overall growth and global developmental delay with impaired intellectual development and that has_material_basis_in compound heterozygous mutations in the GET4 gene on chromosome 7p22.", "url": "https://disease-ontology.org/term/DOID:0051052", "evidence": [ { "id": "0051052", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0051052" } ], "weight": 0.0 } ], "biological_process": [ { "name": "nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration", "id": "GO:0021817", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021817", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5F2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5F2" } ], "pmid": "" }, { "name": "nuclear matrix anchoring at nuclear membrane", "id": "GO:0090292", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090292", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5F2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5F2" } ], "pmid": "" }, { "name": "response to mechanical stimulus", "id": "GO:0009612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009612", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5F2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5F2" } ], "pmid": "" }, { "name": "ossification", "id": "GO:0001503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001503", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5F2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5F2" } ], "pmid": "" }, { "name": "meiotic attachment of telomere to nuclear envelope", "id": "GO:0070197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070197", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5F2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5F2" } ], "pmid": "" }, { "name": "homologous chromosome pairing at meiosis", "id": "GO:0007129", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007129", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5F2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5F2" } ], "pmid": "" }, { "name": "centrosome localization", "id": "GO:0051642", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051642", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5F2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5F2" } ], "pmid": "" }, { "name": "protein insertion into ER membrane", "id": "GO:0045048", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045048", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5F2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5F2" } ], "pmid": "" }, { "name": "post-translational protein targeting to endoplasmic reticulum membrane", "id": "GO:0006620", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006620", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5F2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5F2" } ], "pmid": "" }, { "name": "regulation of protein stability", "id": "GO:0031647", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031647", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5F2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5F2" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5F2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5F2" } ], "pmid": "" }, { "name": "ERAD pathway", "id": "GO:0036503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036503", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5F2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5F2" } ], "pmid": "" }, { "name": "tail-anchored membrane protein insertion into ER membrane", "id": "GO:0071816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071816", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5F2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5F2" } ], "pmid": "" }, { "name": "maintenance of unfolded protein", "id": "GO:0036506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036506", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5F2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5F2" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5F2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5F2" } ], "pmid": "" }, { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5F2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5F2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5F2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5F2" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5F2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5F2" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5F2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5F2" } ], "pmid": "" }, { "name": "acrosomal membrane", "id": "GO:0002080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002080", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5F2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5F2" } ], "pmid": "" }, { "name": "nuclear inner membrane", "id": "GO:0005637", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005637", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5F2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5F2" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5F2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5F2" } ], "pmid": "" }, { "name": "meiotic nuclear membrane microtubule tethering complex", "id": "GO:0034993", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034993", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5F2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5F2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5F2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5F2" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5F2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5F2" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5F2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5F2" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5F2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5F2" } ], "pmid": "" }, { "name": "BAT3 complex", "id": "GO:0071818", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071818", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5F2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5F2" } ], "pmid": "" } ], "molecular_function": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5F2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5F2" } ], "pmid": "" }, { "name": "lamin binding", "id": "GO:0005521", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005521", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5F2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5F2" } ], "pmid": "" }, { "name": "cytoskeleton-nuclear membrane anchor activity", "id": "GO:0140444", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140444", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5F2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5F2" } ], "pmid": "" }, { "name": "protein-folding chaperone binding", "id": "GO:0051087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051087", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5F2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5F2" } ], "pmid": "" }, { "name": "protein carrier chaperone", "id": "GO:0140597", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140597", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5F2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5F2" } ], "pmid": "" }, { "name": "protein-membrane adaptor activity", "id": "GO:0043495", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043495", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5F2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5F2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6A5F2-1", "start_pos": "112", "end_pos": "112", "site_lbl": "Thr112", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 112, "start_aa": "Thr", "end_pos": 112, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr112", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6A5F2-1" }, { "uniprot_canonical_ac": "A0A8I5ZN85-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN85", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN85" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 2526, "chemical_mass": 280633.0, "gene_names": "Jmjd1c;Jmjd1c;Pr2", "protein_name": "Jumonji domain-containing protein 1C", "disease": [ { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN85", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN85" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN85", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN85" } ], "pmid": "" }, { "name": "histone deacetylase complex", "id": "GO:0000118", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000118", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN85", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN85" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN85", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN85" } ], "pmid": "" }, { "name": "histone H3K9 demethylase activity", "id": "GO:0032454", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032454", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN85", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN85" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN85", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN85" } ], "pmid": "" }, { "name": "dioxygenase activity", "id": "GO:0051213", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051213", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN85", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN85" } ], "pmid": "" }, { "name": "chromatin DNA binding", "id": "GO:0031490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031490", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN85", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN85" } ], "pmid": "" }, { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN85", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN85" } ], "pmid": "" }, { "name": "protein demethylase activity", "id": "GO:0140457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140457", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN85", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN85" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN85", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN85" } ], "pmid": "" }, { "name": "maintenance of cell number", "id": "GO:0098727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098727", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN85", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN85" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN85", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN85" } ], "pmid": "" }, { "name": "lipid biosynthetic process", "id": "GO:0008610", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008610", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN85", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN85" } ], "pmid": "" }, { "name": "male gonad development", "id": "GO:0008584", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008584", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN85", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN85" } ], "pmid": "" }, { "name": "seminiferous tubule development", "id": "GO:0072520", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072520", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN85", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN85" } ], "pmid": "" }, { "name": "epithelial cell morphogenesis", "id": "GO:0003382", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003382", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN85", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN85" } ], "pmid": "" }, { "name": "male germ-line stem cell population maintenance", "id": "GO:0036098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036098", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN85", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN85" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I5ZN85-1", "start_pos": "1392", "end_pos": "1392", "site_lbl": "Thr1392", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1392, "start_aa": "Thr", "end_pos": 1392, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1392", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I5ZN85-1" }, { "uniprot_canonical_ac": "A0A8I6ADB5-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ADB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ADB5" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1259, "chemical_mass": 144486.0, "gene_names": "Stag1", "protein_name": "Cohesin subunit SA", "disease": [ { "disease_id": "DOID:0080238", "name": "autosomal dominant intellectual developmental disorder 47", "description": "An autosomal dominant intellectual developmental disorder that has_material_basis_in heterozygous mutation in the STAG1 gene on chromosome 3q22.", "url": "https://disease-ontology.org/term/DOID:0080238", "evidence": [ { "id": "0080238", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080238" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ADB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ADB5" } ], "pmid": "" }, { "name": "chromosome, centromeric region", "id": "GO:0000775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000775", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ADB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ADB5" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ADB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ADB5" } ], "pmid": "" }, { "name": "cohesin complex", "id": "GO:0008278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008278", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ADB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ADB5" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ADB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ADB5" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ADB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ADB5" } ], "pmid": "" }, { "name": "nuclear matrix", "id": "GO:0016363", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016363", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ADB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ADB5" } ], "pmid": "" }, { "name": "mitotic spindle pole", "id": "GO:0097431", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097431", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ADB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ADB5" } ], "pmid": "" } ], "biological_process": [ { "name": "chromosome segregation", "id": "GO:0007059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007059", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ADB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ADB5" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ADB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ADB5" } ], "pmid": "" }, { "name": "sister chromatid cohesion", "id": "GO:0007062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007062", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ADB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ADB5" } ], "pmid": "" }, { "name": "mitotic spindle assembly", "id": "GO:0090307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090307", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ADB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ADB5" } ], "pmid": "" } ], "molecular_function": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ADB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ADB5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6ADB5-1", "start_pos": "1115", "end_pos": "1115", "site_lbl": "Thr1115", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1115, "start_aa": "Thr", "end_pos": 1115, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1115", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6ADB5-1" }, { "uniprot_canonical_ac": "A0A8I6A9T7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A9T7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A9T7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1450, "chemical_mass": 169164.0, "gene_names": "Ccdc18;Ccdc18", "protein_name": "", "disease": [], "biological_process": [ { "name": "positive regulation of adipose tissue development", "id": "GO:1904179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904179", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A9T7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A9T7" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A9T7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A9T7" } ], "pmid": "" }, { "name": "centriolar satellite", "id": "GO:0034451", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034451", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A9T7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A9T7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6A9T7-1" }, { "uniprot_canonical_ac": "A0A8I6A420-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A420", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A420" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 928, "chemical_mass": 101065.0, "gene_names": "Bcas3;Bcas3;RGD1560788", "protein_name": "BCAS3 microtubule associated cell migration factor", "disease": [ { "disease_id": "DOID:0070408", "name": "Hengel-Maroofian-Schols syndrome", "description": "A syndrome characterized by infant or early childhood onset, impaired intellectual development with poor or absent speech, pyramidal signs, microcephaly, short stature, and dysmorphic facial features has_material_basis_in homozygous or compound heterozygous mutation in the BCAS3 gene on chromosome 17q23.", "url": "https://disease-ontology.org/term/DOID:0070408", "evidence": [ { "id": "0070408", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070408" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 } ], "biological_process": [ { "name": "angiogenesis", "id": "GO:0001525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001525", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A420", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A420" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A420", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A420" } ], "pmid": "" }, { "name": "autophagy", "id": "GO:0006914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006914", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A420", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A420" } ], "pmid": "" }, { "name": "cell-cell signaling", "id": "GO:0007267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007267", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A420", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A420" } ], "pmid": "" }, { "name": "regulation of actin cytoskeleton organization", "id": "GO:0032956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032956", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A420", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A420" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A420", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A420" } ], "pmid": "" }, { "name": "positive regulation of endothelial cell migration", "id": "GO:0010595", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010595", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A420", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A420" } ], "pmid": "" }, { "name": "positive regulation of catalytic activity", "id": "GO:0043085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043085", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A420", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A420" } ], "pmid": "" }, { "name": "response to estrogen", "id": "GO:0043627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043627", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A420", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A420" } ], "pmid": "" }, { "name": "cellular response to estrogen stimulus", "id": "GO:0071391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071391", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A420", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A420" } ], "pmid": "" }, { "name": "response to starvation", "id": "GO:0042594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042594", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A420", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A420" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A420", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A420" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A420", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A420" } ], "pmid": "" }, { "name": "phagophore assembly site", "id": "GO:0000407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000407", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A420", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A420" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A420", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A420" } ], "pmid": "" }, { "name": "cell leading edge", "id": "GO:0031252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031252", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A420", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A420" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A420", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A420" } ], "pmid": "" }, { "name": "intermediate filament cytoskeleton", "id": "GO:0045111", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045111", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A420", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A420" } ], "pmid": "" }, { "name": "cytoplasmic microtubule", "id": "GO:0005881", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005881", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A420", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A420" } ], "pmid": "" }, { "name": "euchromatin", "id": "GO:0000791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000791", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A420", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A420" } ], "pmid": "" } ], "molecular_function": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A420", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A420" } ], "pmid": "" }, { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A420", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A420" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A420", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A420" } ], "pmid": "" }, { "name": "beta-tubulin binding", "id": "GO:0048487", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048487", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A420", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A420" } ], "pmid": "" }, { "name": "phosphatidylinositol binding", "id": "GO:0035091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035091", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A420", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A420" } ], "pmid": "" }, { "name": "nuclear receptor binding", "id": "GO:0016922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016922", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A420", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A420" } ], "pmid": "" }, { "name": "acetyltransferase activator activity", "id": "GO:0010698", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010698", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A420", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A420" } ], "pmid": "" }, { "name": "histone acetyltransferase binding", "id": "GO:0035035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035035", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A420", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A420" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6A420-1" }, { "uniprot_canonical_ac": "A0A8I6A2Y2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2Y2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2Y2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 2707, "chemical_mass": 295882.0, "gene_names": "Srrm2;Srrm2", "protein_name": "", "disease": [ { "disease_id": "DOID:0061045", "name": "autosomal dominant intellectual developmental disorder 72", "description": "An autosomal dominant intellectual developmental disorder characterized by developmental delay, predominant speech delay, autistic or attention-deficit/hyperactivity disorder features, overfriendliness, generalized hypotonia, overweight/obesity, and dysmorphic features that has_material_basis_in heterozygous mutation in the SRRM2 gene on chromosome 16p13.", "url": "https://disease-ontology.org/term/DOID:0061045", "evidence": [ { "id": "0061045", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061045" } ], "weight": 0.0 }, { "disease_id": "DOID:14330", "name": "Parkinson's disease", "description": "A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.", "url": "https://disease-ontology.org/term/DOID:14330", "evidence": [ { "id": "14330", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14330" } ], "weight": 0.0 }, { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2Y2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2Y2" } ], "pmid": "" }, { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2Y2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2Y2" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2Y2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2Y2" } ], "pmid": "" }, { "name": "Cajal body", "id": "GO:0015030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015030", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2Y2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2Y2" } ], "pmid": "" }, { "name": "catalytic step 2 spliceosome", "id": "GO:0071013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071013", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2Y2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2Y2" } ], "pmid": "" }, { "name": "U2-type catalytic step 1 spliceosome", "id": "GO:0071006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071006", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2Y2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2Y2" } ], "pmid": "" }, { "name": "U2-type catalytic step 2 spliceosome", "id": "GO:0071007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071007", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2Y2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2Y2" } ], "pmid": "" }, { "name": "post-spliceosomal complex", "id": "GO:0071020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071020", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2Y2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2Y2" } ], "pmid": "" }, { "name": "U2-type precatalytic spliceosome", "id": "GO:0071005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071005", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2Y2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2Y2" } ], "pmid": "" }, { "name": "U12-type catalytic step 2 spliceosome", "id": "GO:0071018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071018", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2Y2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2Y2" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2Y2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2Y2" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2Y2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2Y2" } ], "pmid": "" }, { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2Y2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2Y2" } ], "pmid": "" } ], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2Y2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2Y2" } ], "pmid": "" }, { "name": "C2H2 zinc finger domain binding", "id": "GO:0070742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070742", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2Y2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2Y2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6A2Y2-1", "start_pos": "1010", "end_pos": "1010", "site_lbl": "Thr1010", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1010, "start_aa": "Thr", "end_pos": 1010, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1010", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I6A2Y2-1", "start_pos": "2275", "end_pos": "2275", "site_lbl": "Thr2275", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2275, "start_aa": "Thr", "end_pos": 2275, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2275", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I6A2Y2-1", "start_pos": "2290", "end_pos": "2290", "site_lbl": "Thr2290", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2290, "start_aa": "Thr", "end_pos": 2290, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2290", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I6A2Y2-1", "start_pos": "2540", "end_pos": "2540", "site_lbl": "Thr2540", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2540, "start_aa": "Thr", "end_pos": 2540, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2540", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I6A2Y2-1", "start_pos": "2556", "end_pos": "2556", "site_lbl": "Thr2556", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2556, "start_aa": "Thr", "end_pos": 2556, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2556", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I6A2Y2-1", "start_pos": "364", "end_pos": "364", "site_lbl": "Thr364", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 364, "start_aa": "Thr", "end_pos": 364, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr364", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6A2Y2-1" }, { "uniprot_canonical_ac": "A0A8I6A606-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A606", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A606" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 484, "chemical_mass": 53953.0, "gene_names": "Sufu;Sufu", "protein_name": "Suppressor of fused homolog", "disease": [ { "disease_id": "DOID:0050902", "name": "medulloblastoma", "description": "An infratentorial cancer that is located_in the lower part of the brain and is a type of primitive neuroectodermal tumor.", "url": "https://disease-ontology.org/term/DOID:0050902", "evidence": [ { "id": "0050902", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050902" } ], "weight": 0.0 }, { "disease_id": "DOID:0060071", "name": "pre-malignant neoplasm", "description": "A disease of cellular proliferation that results in abnormal growths in the body, which do not invade or destroy the surrounding tissue but, given enough time, will transform into a cancer.", "url": "https://disease-ontology.org/term/DOID:0060071", "evidence": [ { "id": "0060071", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060071" } ], "weight": 0.0 }, { "disease_id": "DOID:0070366", "name": "nevoid basal cell carcinoma syndrome 2", "description": "A nevoid basal cell carcinoma syndrome that has_material_basis_in heterozygous mutation in the SUFU gene on chromosome 10q24.", "url": "https://disease-ontology.org/term/DOID:0070366", "evidence": [ { "id": "0070366", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070366" } ], "weight": 0.0 }, { "disease_id": "DOID:0080278", "name": "Joubert syndrome 32", "description": "A Joubert syndrome that has_material_basis_in homozygous mutation in the SUFU gene on chromosome 10q24.", "url": "https://disease-ontology.org/term/DOID:0080278", "evidence": [ { "id": "0080278", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080278" } ], "weight": 0.0 }, { "disease_id": "DOID:2512", "name": "nevoid basal cell carcinoma syndrome", "description": "A syndrome characterized by multiple early-onset basal cell carcinoma, multiple jaw keratocysts and skeletal abnormalities.", "url": "https://disease-ontology.org/term/DOID:2512", "evidence": [ { "id": "2512", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2512" } ], "weight": 0.0 }, { "disease_id": "DOID:3073", "name": "brain glioblastoma multiforme", "description": "A brain glioma that has_material_basis_in abnormally proliferating cells derives_from glial cells, has_symptom seizure, headaches, nausea and vomiting, memory loss, changes to personality, mood or concentration; and localized neurological problems.", "url": "https://disease-ontology.org/term/DOID:3073", "evidence": [ { "id": "3073", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3073" } ], "weight": 0.0 }, { "disease_id": "DOID:4586", "name": "familial meningioma", "description": "", "url": "https://disease-ontology.org/term/DOID:4586", "evidence": [ { "id": "4586", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4586" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A606", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A606" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A606", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A606" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A606", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A606" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A606", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A606" } ], "pmid": "" }, { "name": "GLI-SUFU complex", "id": "GO:1990788", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990788", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A606", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A606" } ], "pmid": "" } ], "biological_process": [ { "name": "spinal cord dorsal/ventral patterning", "id": "GO:0021513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021513", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A606", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A606" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A606", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A606" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A606", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A606" } ], "pmid": "" }, { "name": "spermatid development", "id": "GO:0007286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007286", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A606", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A606" } ], "pmid": "" }, { "name": "neural tube closure", "id": "GO:0001843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001843", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A606", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A606" } ], "pmid": "" }, { "name": "ventricular septum development", "id": "GO:0003281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003281", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A606", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A606" } ], "pmid": "" }, { "name": "determination of left/right symmetry", "id": "GO:0007368", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007368", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A606", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A606" } ], "pmid": "" }, { "name": "aorta development", "id": "GO:0035904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035904", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A606", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A606" } ], "pmid": "" }, { "name": "skin development", "id": "GO:0043588", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043588", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A606", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A606" } ], "pmid": "" }, { "name": "coronary vasculature development", "id": "GO:0060976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060976", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A606", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A606" } ], "pmid": "" }, { "name": "heart looping", "id": "GO:0001947", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001947", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A606", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A606" } ], "pmid": "" }, { "name": "smoothened signaling pathway", "id": "GO:0007224", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007224", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A606", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A606" } ], "pmid": "" }, { "name": "negative regulation of ubiquitin-dependent protein catabolic process", "id": "GO:2000059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000059", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A606", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A606" } ], "pmid": "" }, { "name": "negative regulation of smoothened signaling pathway", "id": "GO:0045879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045879", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A606", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A606" } ], "pmid": "" }, { "name": "positive regulation of cellular response to drug", "id": "GO:2001040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001040", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A606", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A606" } ], "pmid": "" }, { "name": "maintenance of protein localization in organelle", "id": "GO:0072595", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072595", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A606", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A606" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A606", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A606" } ], "pmid": "" }, { "name": "beta-catenin binding", "id": "GO:0008013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008013", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A606", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A606" } ], "pmid": "" }, { "name": "protein sequestering activity", "id": "GO:0140311", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140311", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A606", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A606" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6A606-1" }, { "uniprot_canonical_ac": "A0A8I6A330-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A330", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A330" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 361, "chemical_mass": 40458.0, "gene_names": "Abhd12b;Abhd12b;Bem46l3", "protein_name": "", "disease": [], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A330", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A330" } ], "pmid": "" } ], "molecular_function": [ { "name": "monoacylglycerol lipase activity", "id": "GO:0047372", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047372", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A330", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A330" } ], "pmid": "" }, { "name": "phosphatidylcholine lysophospholipase activity", "id": "GO:0004622", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004622", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A330", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A330" } ], "pmid": "" } ], "biological_process": [ { "name": "monoacylglycerol catabolic process", "id": "GO:0052651", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052651", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A330", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A330" } ], "pmid": "" }, { "name": "phosphatidylserine catabolic process", "id": "GO:0006660", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006660", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A330", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A330" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6A330-1" }, { "uniprot_canonical_ac": "A0A8I6A0T8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A0T8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A0T8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 396, "chemical_mass": 44634.0, "gene_names": "Serpinb9;Serpinb9", "protein_name": "", "disease": [], "molecular_function": [ { "name": "serine-type endopeptidase inhibitor activity", "id": "GO:0004867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004867", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A0T8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A0T8" } ], "pmid": "" }, { "name": "protease binding", "id": "GO:0002020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002020", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A0T8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A0T8" } ], "pmid": "" }, { "name": "cysteine-type endopeptidase inhibitor activity involved in apoptotic process", "id": "GO:0043027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043027", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A0T8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A0T8" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A0T8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A0T8" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A0T8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A0T8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A0T8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A0T8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A0T8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A0T8" } ], "pmid": "" } ], "biological_process": [ { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A0T8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A0T8" } ], "pmid": "" }, { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A0T8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A0T8" } ], "pmid": "" }, { "name": "protection from natural killer cell mediated cytotoxicity", "id": "GO:0042270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A0T8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A0T8" } ], "pmid": "" }, { "name": "defense response to bacterium", "id": "GO:0042742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042742", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A0T8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A0T8" } ], "pmid": "" }, { "name": "acute inflammatory response to antigenic stimulus", "id": "GO:0002438", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002438", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A0T8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A0T8" } ], "pmid": "" }, { "name": "cellular response to estrogen stimulus", "id": "GO:0071391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071391", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A0T8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A0T8" } ], "pmid": "" }, { "name": "T cell mediated cytotoxicity", "id": "GO:0001913", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001913", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A0T8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A0T8" } ], "pmid": "" }, { "name": "negative regulation of T cell apoptotic process", "id": "GO:0070233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070233", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A0T8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A0T8" } ], "pmid": "" }, { "name": "mast cell mediated immunity", "id": "GO:0002448", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002448", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A0T8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A0T8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6A0T8-1" }, { "uniprot_canonical_ac": "A0A8I5XVN6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XVN6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XVN6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1151, "chemical_mass": 128569.0, "gene_names": "LOC689526;LOC689526", "protein_name": "SPATA31 domain-containing protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5XVN6-1" }, { "uniprot_canonical_ac": "A0A8I5XVC5-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XVC5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XVC5" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1561, "chemical_mass": 174725.0, "gene_names": "Limch1;Limch1;RGD1305269", "protein_name": "", "disease": [], "molecular_function": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XVC5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XVC5" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XVC5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XVC5" } ], "pmid": "" }, { "name": "myosin II head/neck binding", "id": "GO:0032034", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032034", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XVC5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XVC5" } ], "pmid": "" } ], "biological_process": [ { "name": "actomyosin structure organization", "id": "GO:0031032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031032", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XVC5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XVC5" } ], "pmid": "" }, { "name": "regulation of focal adhesion assembly", "id": "GO:0051893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051893", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XVC5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XVC5" } ], "pmid": "" }, { "name": "cytoplasmic actin-based contraction involved in cell motility", "id": "GO:0060327", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060327", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XVC5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XVC5" } ], "pmid": "" }, { "name": "positive regulation of protein phosphorylation", "id": "GO:0001934", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001934", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XVC5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XVC5" } ], "pmid": "" }, { "name": "negative regulation of cell migration", "id": "GO:0030336", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030336", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XVC5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XVC5" } ], "pmid": "" }, { "name": "positive regulation of stress fiber assembly", "id": "GO:0051496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051496", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XVC5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XVC5" } ], "pmid": "" }, { "name": "positive regulation of macromolecule metabolic process", "id": "GO:0010604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010604", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XVC5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XVC5" } ], "pmid": "" }, { "name": "regulation of primary metabolic process", "id": "GO:0080090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0080090", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XVC5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XVC5" } ], "pmid": "" } ], "cellular_component": [ { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XVC5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XVC5" } ], "pmid": "" }, { "name": "stress fiber", "id": "GO:0001725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001725", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XVC5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XVC5" } ], "pmid": "" }, { "name": "myosin II complex", "id": "GO:0016460", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016460", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XVC5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XVC5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I5XVC5-1", "start_pos": "1472", "end_pos": "1472", "site_lbl": "Thr1472", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1472, "start_aa": "Thr", "end_pos": 1472, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1472", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I5XVC5-1" }, { "uniprot_canonical_ac": "A0A8I5ZQK4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQK4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQK4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 616, "chemical_mass": 71776.0, "gene_names": "ENSRNOG00000066827;ENSRNOG00000068563;LOC120094816;LOC134480626;Zfp1007l1;Zfp950l2;LOC102550711;LOC102556463;LOC120094815;LOC120094816;LOC134478907;LOC134480626;LOC134480627;Zfp1007l1;Zfp950l2;Znf431l1", "protein_name": "Zinc finger protein 431-like", "disease": [], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQK4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQK4" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQK4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQK4" } ], "pmid": "" }, { "name": "sequence-specific double-stranded DNA binding", "id": "GO:1990837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990837", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQK4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQK4" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQK4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQK4" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQK4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQK4" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQK4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQK4" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQK4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQK4" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQK4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQK4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZQK4-1" }, { "uniprot_canonical_ac": "A0A8I5ZMP0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMP0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMP0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1853, "chemical_mass": 203850.0, "gene_names": "Mast2", "protein_name": "non-specific serine/threonine protein kinase", "disease": [], "molecular_function": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMP0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMP0" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMP0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMP0" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMP0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMP0" } ], "pmid": "" }, { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMP0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMP0" } ], "pmid": "" }, { "name": "phosphatase binding", "id": "GO:0019902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019902", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMP0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMP0" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMP0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMP0" } ], "pmid": "" }, { "name": "microtubule cytoskeleton", "id": "GO:0015630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015630", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMP0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMP0" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMP0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMP0" } ], "pmid": "" }, { "name": "cytoskeleton organization", "id": "GO:0007010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007010", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMP0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMP0" } ], "pmid": "" }, { "name": "protein phosphorylation", "id": "GO:0006468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006468", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMP0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMP0" } ], "pmid": "" }, { "name": "regulation of interleukin-12 production", "id": "GO:0032655", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032655", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMP0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMP0" } ], "pmid": "" }, { "name": "spermatid differentiation", "id": "GO:0048515", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048515", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMP0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMP0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I5ZMP0-1", "start_pos": "1663", "end_pos": "1663", "site_lbl": "Thr1663", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1663, "start_aa": "Thr", "end_pos": 1663, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1663", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I5ZMP0-1", "start_pos": "1666", "end_pos": "1666", "site_lbl": "Thr1666", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1666, "start_aa": "Thr", "end_pos": 1666, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1666", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I5ZMP0-1", "start_pos": "1743", "end_pos": "1743", "site_lbl": "Thr1743", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "reported site T1599 is on non-canonical isoform A0A8I5ZUU6-1 which maps to canonical isoform site A0A8I5ZMP0-1:1743", "icn3d_view": {}, "start_pos": 1743, "start_aa": "Thr", "end_pos": 1743, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1743", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I5ZMP0-1", "start_pos": "1746", "end_pos": "1746", "site_lbl": "Thr1746", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "reported site T1602 is on non-canonical isoform A0A8I5ZUU6-1 which maps to canonical isoform site A0A8I5ZMP0-1:1746", "icn3d_view": {}, "start_pos": 1746, "start_aa": "Thr", "end_pos": 1746, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1746", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I5ZMP0-1" }, { "uniprot_canonical_ac": "A0A8I5ZN32-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN32", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN32" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 753, "chemical_mass": 83228.0, "gene_names": "Rap1gap;Rap1ga1;Rap1gap", "protein_name": "", "disease": [ { "disease_id": "DOID:0050908", "name": "myelodysplastic syndrome", "description": "A bone marrow cancer that is characterized by under production of white blood cells, red blood cells and platelets.", "url": "https://disease-ontology.org/term/DOID:0050908", "evidence": [ { "id": "0050908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050908" } ], "weight": 0.0 }, { "disease_id": "DOID:1312", "name": "focal segmental glomerulosclerosis", "description": "", "url": "https://disease-ontology.org/term/DOID:1312", "evidence": [ { "id": "1312", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1312" } ], "weight": 0.0 }, { "disease_id": "DOID:1793", "name": "pancreatic cancer", "description": "An endocrine gland cancer located_in the pancreas.", "url": "https://disease-ontology.org/term/DOID:1793", "evidence": [ { "id": "1793", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1793" } ], "weight": 0.0 }, { "disease_id": "DOID:1909", "name": "melanoma", "description": "A cell type cancer that has_material_basis_in abnormally proliferating cells derives_from melanocytes which are found in skin, the bowel and the eye.", "url": "https://disease-ontology.org/term/DOID:1909", "evidence": [ { "id": "1909", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1909" } ], "weight": 0.0 }, { "disease_id": "DOID:3312", "name": "bipolar disorder", "description": "A mood disorder that involves alternating periods of mania and depression.", "url": "https://disease-ontology.org/term/DOID:3312", "evidence": [ { "id": "3312", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3312" } ], "weight": 0.0 }, { "disease_id": "DOID:3969", "name": "papillary thyroid carcinoma", "description": "A differentiated thyroid gland carcinoma that is characterized by the small mushroom shape of the tumor which has a stem attached to the epithelial layer and arises from the follicular cells of the thyroid gland.", "url": "https://disease-ontology.org/term/DOID:3969", "evidence": [ { "id": "3969", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3969" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN32", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN32" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN32", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN32" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN32", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN32" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of small GTPase mediated signal transduction", "id": "GO:0051056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051056", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN32", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN32" } ], "pmid": "" }, { "name": "regulation of cell-cell adhesion", "id": "GO:0022407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022407", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN32", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN32" } ], "pmid": "" }, { "name": "positive regulation of cell-cell adhesion", "id": "GO:0022409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022409", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN32", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN32" } ], "pmid": "" }, { "name": "negative regulation of microvillus assembly", "id": "GO:1903697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903697", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN32", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN32" } ], "pmid": "" }, { "name": "positive regulation of GTPase activity", "id": "GO:0043547", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043547", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN32", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN32" } ], "pmid": "" }, { "name": "negative regulation of neuron differentiation", "id": "GO:0045665", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045665", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN32", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN32" } ], "pmid": "" }, { "name": "positive regulation of phagocytosis", "id": "GO:0050766", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050766", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN32", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN32" } ], "pmid": "" }, { "name": "negative regulation of thyroid gland epithelial cell proliferation", "id": "GO:1904442", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904442", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN32", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN32" } ], "pmid": "" }, { "name": "cellular response to glial cell derived neurotrophic factor", "id": "GO:1990792", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990792", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN32", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN32" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN32", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN32" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN32", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN32" } ], "pmid": "" }, { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN32", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN32" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN32", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN32" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN32", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN32" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN32", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN32" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN32", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN32" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZN32-1" }, { "uniprot_canonical_ac": "A0A8I5ZSV2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZSV2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZSV2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 269, "chemical_mass": 29368.0, "gene_names": "Commd4", "protein_name": "", "disease": [], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZSV2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZSV2" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZSV2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZSV2" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZSV2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZSV2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZSV2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZSV2" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZSV2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZSV2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I5ZSV2-1", "start_pos": "39", "end_pos": "39", "site_lbl": "Thr39", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 39, "start_aa": "Thr", "end_pos": 39, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr39", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I5ZSV2-1" }, { "uniprot_canonical_ac": "A0A8I6A9H4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A9H4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A9H4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 433, "chemical_mass": 48206.0, "gene_names": "Art3", "protein_name": "NAD(P)(+)--arginine ADP-ribosyltransferase", "disease": [], "molecular_function": [ { "name": "nucleotidyltransferase activity", "id": "GO:0016779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016779", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A9H4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A9H4" } ], "pmid": "" }, { "name": "NAD+-protein-arginine ADP-ribosyltransferase activity", "id": "GO:0106274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106274", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A9H4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A9H4" } ], "pmid": "" }, { "name": "NAD+ poly-ADP-ribosyltransferase activity", "id": "GO:0003950", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003950", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A9H4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A9H4" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A9H4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A9H4" } ], "pmid": "" }, { "name": "side of membrane", "id": "GO:0098552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098552", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A9H4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A9H4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6A9H4-1", "start_pos": "391", "end_pos": "391", "site_lbl": "Thr391", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 391, "start_aa": "Thr", "end_pos": 391, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr391", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6A9H4-1" }, { "uniprot_canonical_ac": "A0A8I5Y9U2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y9U2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y9U2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 553, "chemical_mass": 61081.0, "gene_names": "Cnot2", "protein_name": "CCR4-NOT transcription complex subunit 2", "disease": [], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y9U2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y9U2" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y9U2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y9U2" } ], "pmid": "" }, { "name": "regulation of stem cell population maintenance", "id": "GO:2000036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000036", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y9U2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y9U2" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y9U2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y9U2" } ], "pmid": "" }, { "name": "trophectodermal cell differentiation", "id": "GO:0001829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y9U2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y9U2" } ], "pmid": "" }, { "name": "positive regulation of cytoplasmic mRNA processing body assembly", "id": "GO:0010606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010606", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y9U2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y9U2" } ], "pmid": "" }, { "name": "negative regulation of intracellular estrogen receptor signaling pathway", "id": "GO:0033147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033147", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y9U2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y9U2" } ], "pmid": "" }, { "name": "nuclear-transcribed mRNA poly(A) tail shortening", "id": "GO:0000289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000289", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y9U2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y9U2" } ], "pmid": "" } ], "cellular_component": [ { "name": "CCR4-NOT core complex", "id": "GO:0030015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030015", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y9U2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y9U2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y9U2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y9U2" } ], "pmid": "" }, { "name": "P-body", "id": "GO:0000932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000932", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y9U2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y9U2" } ], "pmid": "" }, { "name": "CCR4-NOT complex", "id": "GO:0030014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030014", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y9U2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y9U2" } ], "pmid": "" } ], "molecular_function": [ { "name": "poly(A)-specific ribonuclease activity", "id": "GO:0004535", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004535", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y9U2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y9U2" } ], "pmid": "" }, { "name": "transcription corepressor binding", "id": "GO:0001222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001222", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y9U2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y9U2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I5Y9U2-1", "start_pos": "126", "end_pos": "126", "site_lbl": "Thr126", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 126, "start_aa": "Thr", "end_pos": 126, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr126", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I5Y9U2-1" }, { "uniprot_canonical_ac": "A0A8I6A4F2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A4F2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A4F2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 656, "chemical_mass": 73766.0, "gene_names": "Ints9", "protein_name": "Integrator complex subunit 9", "disease": [], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A4F2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A4F2" } ], "pmid": "" }, { "name": "integrator complex", "id": "GO:0032039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032039", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A4F2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A4F2" } ], "pmid": "" }, { "name": "INTAC complex", "id": "GO:0160232", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160232", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A4F2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A4F2" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A4F2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A4F2" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A4F2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A4F2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A4F2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A4F2" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway", "id": "GO:0090101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090101", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A4F2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A4F2" } ], "pmid": "" }, { "name": "regulation of cellular response to growth factor stimulus", "id": "GO:0090287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090287", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A4F2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A4F2" } ], "pmid": "" }, { "name": "snRNA 3'-end processing", "id": "GO:0034472", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034472", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A4F2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A4F2" } ], "pmid": "" }, { "name": "RNA polymerase II transcription initiation surveillance", "id": "GO:0160240", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160240", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A4F2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A4F2" } ], "pmid": "" }, { "name": "regulation of transcription elongation by RNA polymerase II", "id": "GO:0034243", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034243", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A4F2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A4F2" } ], "pmid": "" }, { "name": "negative regulation of transforming growth factor beta receptor signaling pathway", "id": "GO:0030512", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030512", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A4F2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A4F2" } ], "pmid": "" }, { "name": "snRNA processing", "id": "GO:0016180", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016180", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A4F2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A4F2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6A4F2-1" }, { "uniprot_canonical_ac": "A0A8I5ZYG1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYG1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYG1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 903, "chemical_mass": 102251.0, "gene_names": "Osbpl5", "protein_name": "Oxysterol-binding protein", "disease": [], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYG1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYG1" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYG1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYG1" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYG1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYG1" } ], "pmid": "" }, { "name": "endoplasmic reticulum-plasma membrane contact site", "id": "GO:0140268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140268", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYG1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYG1" } ], "pmid": "" }, { "name": "transporter complex", "id": "GO:1990351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990351", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYG1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYG1" } ], "pmid": "" } ], "molecular_function": [ { "name": "cholesterol binding", "id": "GO:0015485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015485", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYG1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYG1" } ], "pmid": "" }, { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYG1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYG1" } ], "pmid": "" }, { "name": "phosphatidylinositol-4-phosphate binding", "id": "GO:0070273", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070273", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYG1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYG1" } ], "pmid": "" }, { "name": "phosphatidylserine binding", "id": "GO:0001786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001786", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYG1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYG1" } ], "pmid": "" }, { "name": "phosphatidylserine transfer activity", "id": "GO:0140343", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140343", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYG1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYG1" } ], "pmid": "" }, { "name": "phosphatidylserine-phosphatidylinositol-4-phosphate exchange activity", "id": "GO:0160270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYG1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYG1" } ], "pmid": "" } ], "biological_process": [ { "name": "phospholipid transport", "id": "GO:0015914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015914", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYG1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYG1" } ], "pmid": "" }, { "name": "lipid transport", "id": "GO:0006869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006869", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYG1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYG1" } ], "pmid": "" }, { "name": "intermembrane phospholipid transfer", "id": "GO:0120010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120010", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYG1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYG1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I5ZYG1-1", "start_pos": "73", "end_pos": "73", "site_lbl": "Thr73", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 73, "start_aa": "Thr", "end_pos": 73, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr73", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I5ZYG1-1" }, { "uniprot_canonical_ac": "A0A8I6GKW7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GKW7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GKW7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 926, "chemical_mass": 106346.0, "gene_names": "Rig1;Ddx58;Rig1;Rigi", "protein_name": "Antiviral innate immune response receptor RIG-I", "disease": [ { "disease_id": "DOID:13636", "name": "Fanconi anemia", "description": "A congenital hypoplastic anemia characterized by progressive pancytopenia with bone marrow failure, variable congenital malformations and predisposition to develop hematological or solid tumors. It is a result of a genetic defect in a cluster of proteins responsible for DNA repair.", "url": "https://disease-ontology.org/term/DOID:13636", "evidence": [ { "id": "13636", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13636" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GKW7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GKW7" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GKW7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GKW7" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GKW7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GKW7" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GKW7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GKW7" } ], "pmid": "" }, { "name": "RNA helicase activity", "id": "GO:0003724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003724", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GKW7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GKW7" } ], "pmid": "" }, { "name": "double-stranded RNA binding", "id": "GO:0003725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003725", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GKW7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GKW7" } ], "pmid": "" }, { "name": "single-stranded RNA binding", "id": "GO:0003727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003727", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GKW7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GKW7" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GKW7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GKW7" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GKW7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GKW7" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GKW7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GKW7" } ], "pmid": "" }, { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GKW7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GKW7" } ], "pmid": "" }, { "name": "double-stranded DNA binding", "id": "GO:0003690", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003690", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GKW7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GKW7" } ], "pmid": "" }, { "name": "pattern recognition receptor activity", "id": "GO:0038187", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038187", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GKW7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GKW7" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GKW7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GKW7" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GKW7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GKW7" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GKW7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GKW7" } ], "pmid": "" }, { "name": "bicellular tight junction", "id": "GO:0005923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005923", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GKW7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GKW7" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GKW7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GKW7" } ], "pmid": "" }, { "name": "ruffle membrane", "id": "GO:0032587", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032587", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GKW7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GKW7" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GKW7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GKW7" } ], "pmid": "" } ], "biological_process": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GKW7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GKW7" } ], "pmid": "" }, { "name": "defense response to virus", "id": "GO:0051607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051607", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GKW7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GKW7" } ], "pmid": "" }, { "name": "cytoplasmic pattern recognition receptor signaling pathway", "id": "GO:0002753", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002753", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GKW7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GKW7" } ], "pmid": "" }, { "name": "antiviral innate immune response", "id": "GO:0140374", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140374", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GKW7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GKW7" } ], "pmid": "" }, { "name": "cellular response to exogenous dsRNA", "id": "GO:0071360", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071360", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GKW7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GKW7" } ], "pmid": "" }, { "name": "positive regulation of interferon-alpha production", "id": "GO:0032727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032727", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GKW7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GKW7" } ], "pmid": "" }, { "name": "positive regulation of response to cytokine stimulus", "id": "GO:0060760", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060760", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GKW7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GKW7" } ], "pmid": "" }, { "name": "positive regulation of gene expression", "id": "GO:0010628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010628", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GKW7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GKW7" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GKW7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GKW7" } ], "pmid": "" }, { "name": "positive regulation of interleukin-6 production", "id": "GO:0032755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032755", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GKW7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GKW7" } ], "pmid": "" }, { "name": "response to virus", "id": "GO:0009615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009615", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GKW7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GKW7" } ], "pmid": "" }, { "name": "positive regulation of defense response to virus by host", "id": "GO:0002230", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002230", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GKW7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GKW7" } ], "pmid": "" }, { "name": "regulation of cell migration", "id": "GO:0030334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030334", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GKW7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GKW7" } ], "pmid": "" }, { "name": "positive regulation of tumor necrosis factor production", "id": "GO:0032760", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032760", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GKW7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GKW7" } ], "pmid": "" }, { "name": "response to exogenous dsRNA", "id": "GO:0043330", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043330", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GKW7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GKW7" } ], "pmid": "" }, { "name": "positive regulation of interleukin-8 production", "id": "GO:0032757", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032757", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GKW7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GKW7" } ], "pmid": "" }, { "name": "detection of virus", "id": "GO:0009597", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009597", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GKW7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GKW7" } ], "pmid": "" }, { "name": "positive regulation of granulocyte macrophage colony-stimulating factor production", "id": "GO:0032725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032725", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GKW7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GKW7" } ], "pmid": "" }, { "name": "RIG-I signaling pathway", "id": "GO:0039529", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0039529", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GKW7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GKW7" } ], "pmid": "" }, { "name": "gene expression", "id": "GO:0010467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010467", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GKW7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GKW7" } ], "pmid": "" }, { "name": "positive regulation of interferon-beta production", "id": "GO:0032728", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032728", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GKW7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GKW7" } ], "pmid": "" }, { "name": "positive regulation of myeloid dendritic cell cytokine production", "id": "GO:0002735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002735", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GKW7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GKW7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6GKW7-1" }, { "uniprot_canonical_ac": "A0A8I5YB95-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YB95", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YB95" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 308, "chemical_mass": 33647.0, "gene_names": "Dctn3;Dctn3l1", "protein_name": "", "disease": [], "cellular_component": [ { "name": "dynactin complex", "id": "GO:0005869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005869", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YB95", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YB95" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YB95", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YB95" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YB95", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YB95" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YB95", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YB95" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YB95", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YB95" } ], "pmid": "" }, { "name": "microtubule associated complex", "id": "GO:0005875", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005875", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YB95", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YB95" } ], "pmid": "" } ], "biological_process": [ { "name": "cytoskeleton-dependent cytokinesis", "id": "GO:0061640", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061640", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YB95", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YB95" } ], "pmid": "" }, { "name": "microtubule-based process", "id": "GO:0007017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007017", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YB95", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YB95" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5YB95-1" }, { "uniprot_canonical_ac": "A0A8I5ZMX2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMX2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMX2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1203, "chemical_mass": 135079.0, "gene_names": "Adamts3;Adamts3", "protein_name": "", "disease": [ { "disease_id": "DOID:0060366", "name": "Hennekam syndrome", "description": "A lymphatic system disease characterized by he presence of intestinal lymphangiectasia, mental retardation, and characteristic facial anomalies. It is inherited in an autosomal recessive pattern. Most individuals with Hennekam syndrome have characteristic facial abnormalities, such as a flat face with accompanying puffy eyelids and hypertelorism; the nasal bridge is typically flat and the ears are typically small. Congenital extremity and genital lymphedema is present in most patients.", "url": "https://disease-ontology.org/term/DOID:0060366", "evidence": [ { "id": "0060366", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060366" } ], "weight": 0.0 } ], "biological_process": [ { "name": "in utero embryonic development", "id": "GO:0001701", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001701", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMX2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMX2" } ], "pmid": "" }, { "name": "protein processing", "id": "GO:0016485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016485", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMX2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMX2" } ], "pmid": "" }, { "name": "extracellular matrix organization", "id": "GO:0030198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030198", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMX2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMX2" } ], "pmid": "" }, { "name": "vascular endothelial growth factor production", "id": "GO:0010573", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010573", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMX2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMX2" } ], "pmid": "" }, { "name": "collagen biosynthetic process", "id": "GO:0032964", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032964", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMX2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMX2" } ], "pmid": "" }, { "name": "positive regulation of vascular endothelial growth factor signaling pathway", "id": "GO:1900748", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900748", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMX2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMX2" } ], "pmid": "" }, { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMX2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMX2" } ], "pmid": "" }, { "name": "collagen fibril organization", "id": "GO:0030199", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030199", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMX2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMX2" } ], "pmid": "" } ], "molecular_function": [ { "name": "endopeptidase activity", "id": "GO:0004175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004175", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMX2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMX2" } ], "pmid": "" }, { "name": "metalloendopeptidase activity", "id": "GO:0004222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004222", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMX2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMX2" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMX2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMX2" } ], "pmid": "" }, { "name": "peptidase activity", "id": "GO:0008233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008233", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMX2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMX2" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMX2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMX2" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMX2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMX2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZMX2-1" }, { "uniprot_canonical_ac": "A0A8I6AC90-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AC90", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AC90" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1523, "chemical_mass": 170465.0, "gene_names": "Myom2;Myom2", "protein_name": "", "disease": [], "molecular_function": [ { "name": "kinase binding", "id": "GO:0019900", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019900", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AC90", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AC90" } ], "pmid": "" }, { "name": "structural constituent of muscle", "id": "GO:0008307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008307", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AC90", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AC90" } ], "pmid": "" } ], "cellular_component": [ { "name": "M band", "id": "GO:0031430", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031430", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AC90", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AC90" } ], "pmid": "" } ], "biological_process": [ { "name": "sarcomere organization", "id": "GO:0045214", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045214", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AC90", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AC90" } ], "pmid": "" }, { "name": "extraocular skeletal muscle development", "id": "GO:0002074", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002074", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AC90", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AC90" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6AC90-1", "start_pos": "659", "end_pos": "659", "site_lbl": "Thr659", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 659, "start_aa": "Thr", "end_pos": 659, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr659", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6AC90-1" }, { "uniprot_canonical_ac": "A0A8I6AGY8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AGY8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AGY8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 818, "chemical_mass": 91714.0, "gene_names": "Gtf3c4;Gtf3c4", "protein_name": "", "disease": [], "cellular_component": [ { "name": "transcription factor TFIIIC complex", "id": "GO:0000127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000127", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AGY8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AGY8" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AGY8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AGY8" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AGY8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AGY8" } ], "pmid": "" } ], "molecular_function": [ { "name": "histone acetyltransferase activity", "id": "GO:0004402", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004402", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AGY8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AGY8" } ], "pmid": "" }, { "name": "RNA polymerase III general transcription initiation factor activity", "id": "GO:0000995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000995", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AGY8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AGY8" } ], "pmid": "" }, { "name": "histone H3K14 acetyltransferase activity", "id": "GO:0036408", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036408", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AGY8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AGY8" } ], "pmid": "" } ], "biological_process": [ { "name": "transcription initiation at RNA polymerase III promoter", "id": "GO:0006384", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006384", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AGY8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AGY8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AGY8-1" }, { "uniprot_canonical_ac": "A0A096MJ64-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A096MJ64", "url": "https://www.uniprot.org/uniprotkb/A0A096MJ64" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 429, "chemical_mass": 47337.0, "gene_names": "Sh2d5;RGD1305952;Sh2d5", "protein_name": "SH2 domain-containing protein 5", "disease": [], "cellular_component": [ { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "A0A096MJ64", "url": "https://www.uniprot.org/uniprotkb/A0A096MJ64" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A096MJ64-1" }, { "uniprot_canonical_ac": "A0A8I5ZMM2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMM2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMM2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 2321, "chemical_mass": 253328.0, "gene_names": "Cad;Cad", "protein_name": "Multifunctional protein CAD", "disease": [ { "disease_id": "DOID:0050833", "name": "orotic aciduria", "description": "A pyrimidine metabolic disorder that is characterized by an excessive secretion of orotic acid in urine.", "url": "https://disease-ontology.org/term/DOID:0050833", "evidence": [ { "id": "0050833", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050833" } ], "weight": 0.0 }, { "disease_id": "DOID:0080419", "name": "developmental and epileptic encephalopathy 50", "description": "A developmental and epileptic encephalopathy characterized by delayed psychomotor development, early-onset seizures, severe developmental regression, and normocytic anemia that has_material_basis_in homozygous or compound heterozygous mutation in the CAD gene on chromosome 2p23.", "url": "https://disease-ontology.org/term/DOID:0080419", "evidence": [ { "id": "0080419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080419" } ], "weight": 0.0 }, { "disease_id": "DOID:3247", "name": "rhabdomyosarcoma", "description": "A skeletal muscle cancer that arise from skeletal muscle progenitors.", "url": "https://disease-ontology.org/term/DOID:3247", "evidence": [ { "id": "3247", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3247" } ], "weight": 0.0 }, { "disease_id": "DOID:4450", "name": "renal cell carcinoma", "description": "A renal carcinoma that has_material_basis_in the lining of the proximal convoluted renal tubule of the kidney.", "url": "https://disease-ontology.org/term/DOID:4450", "evidence": [ { "id": "4450", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4450" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:9280", "name": "carbamoyl phosphate synthetase I deficiency disease", "description": "A urea cycle disorder that involves accumulation of ammonia in the blood.", "url": "https://disease-ontology.org/term/DOID:9280", "evidence": [ { "id": "9280", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9280" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "carbamoyl-phosphate synthase (ammonia) activity", "id": "GO:0004087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004087", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMM2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMM2" } ], "pmid": "" }, { "name": "carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity", "id": "GO:0004088", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004088", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMM2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMM2" } ], "pmid": "" }, { "name": "dihydroorotase activity", "id": "GO:0004151", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004151", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMM2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMM2" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMM2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMM2" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMM2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMM2" } ], "pmid": "" }, { "name": "amino acid binding", "id": "GO:0016597", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016597", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMM2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMM2" } ], "pmid": "" }, { "name": "aspartate carbamoyltransferase activity", "id": "GO:0004070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004070", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMM2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMM2" } ], "pmid": "" }, { "name": "glutaminase activity", "id": "GO:0004359", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004359", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMM2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMM2" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMM2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMM2" } ], "pmid": "" }, { "name": "enzyme binding", "id": "GO:0019899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019899", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMM2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMM2" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMM2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMM2" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMM2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMM2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMM2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMM2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMM2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMM2" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMM2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMM2" } ], "pmid": "" }, { "name": "terminal bouton", "id": "GO:0043195", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043195", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMM2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMM2" } ], "pmid": "" }, { "name": "nuclear matrix", "id": "GO:0016363", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016363", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMM2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMM2" } ], "pmid": "" }, { "name": "cell projection", "id": "GO:0042995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042995", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMM2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMM2" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMM2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMM2" } ], "pmid": "" } ], "biological_process": [ { "name": "amino acid metabolic process", "id": "GO:0006520", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006520", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMM2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMM2" } ], "pmid": "" }, { "name": "glutamine metabolic process", "id": "GO:0006541", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006541", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMM2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMM2" } ], "pmid": "" }, { "name": "'de novo' pyrimidine nucleobase biosynthetic process", "id": "GO:0006207", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006207", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMM2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMM2" } ], "pmid": "" }, { "name": "'de novo' UMP biosynthetic process", "id": "GO:0044205", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044205", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMM2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMM2" } ], "pmid": "" }, { "name": "citrulline biosynthetic process", "id": "GO:0019240", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019240", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMM2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMM2" } ], "pmid": "" }, { "name": "liver development", "id": "GO:0001889", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001889", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMM2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMM2" } ], "pmid": "" }, { "name": "heart development", "id": "GO:0007507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007507", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMM2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMM2" } ], "pmid": "" }, { "name": "response to starvation", "id": "GO:0042594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042594", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMM2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMM2" } ], "pmid": "" }, { "name": "response to caffeine", "id": "GO:0031000", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031000", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMM2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMM2" } ], "pmid": "" }, { "name": "cellular response to xenobiotic stimulus", "id": "GO:0071466", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071466", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMM2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMM2" } ], "pmid": "" }, { "name": "xenobiotic metabolic process", "id": "GO:0006805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006805", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMM2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMM2" } ], "pmid": "" }, { "name": "female pregnancy", "id": "GO:0007565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007565", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMM2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMM2" } ], "pmid": "" }, { "name": "response to insulin", "id": "GO:0032868", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032868", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMM2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMM2" } ], "pmid": "" }, { "name": "lactation", "id": "GO:0007595", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007595", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMM2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMM2" } ], "pmid": "" }, { "name": "animal organ regeneration", "id": "GO:0031100", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031100", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMM2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMM2" } ], "pmid": "" }, { "name": "cellular response to epidermal growth factor stimulus", "id": "GO:0071364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071364", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMM2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMM2" } ], "pmid": "" }, { "name": "response to amine", "id": "GO:0014075", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014075", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMM2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMM2" } ], "pmid": "" }, { "name": "response to cortisol", "id": "GO:0051414", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051414", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMM2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMM2" } ], "pmid": "" }, { "name": "response to testosterone", "id": "GO:0033574", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033574", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMM2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMM2" } ], "pmid": "" }, { "name": "UTP biosynthetic process", "id": "GO:0006228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006228", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMM2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMM2" } ], "pmid": "" }, { "name": "UDP biosynthetic process", "id": "GO:0006225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006225", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMM2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMM2" } ], "pmid": "" }, { "name": "pyrimidine nucleotide biosynthetic process", "id": "GO:0006221", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006221", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMM2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMM2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I5ZMM2-1", "start_pos": "173", "end_pos": "173", "site_lbl": "Thr173", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 173, "start_aa": "Thr", "end_pos": 173, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr173", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I5ZMM2-1", "start_pos": "1903", "end_pos": "1903", "site_lbl": "Thr1903", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1903, "start_aa": "Thr", "end_pos": 1903, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1903", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I5ZMM2-1", "start_pos": "51", "end_pos": "51", "site_lbl": "Thr51", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 51, "start_aa": "Thr", "end_pos": 51, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr51", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I5ZMM2-1" }, { "uniprot_canonical_ac": "A0A8I5YBG5-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YBG5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YBG5" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1755, "chemical_mass": 199017.0, "gene_names": "Ubr2;Ubr2", "protein_name": "E3 ubiquitin-protein ligase", "disease": [ { "disease_id": "DOID:0080208", "name": "metabolic dysfunction-associated steatotic liver disease", "description": "A steatotic liver disease characterized by at least one of five specified cardiometabolic risk factors and no other discernible cause with normal to no alcohol use. The five cardiometabolic risk factors are: (1) higher than normal body mass index or waist circumference; (2) higher than normal serum glucose or glycated hemoglobin level, or type 2 diabetes; (3) higher than normal blood pressure or hypertensive treatment; (4) higher than normal plasma triglycerides or lipid lowering treatment; and (5) lower than normal plasma high-density lipoprotein cholesterol.", "url": "https://disease-ontology.org/term/DOID:0080208", "evidence": [ { "id": "0080208", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080208" } ], "weight": 0.0 }, { "disease_id": "DOID:1289", "name": "neurodegenerative disease", "description": "A central nervous system disease that results in the progressive deterioration of function or structure of neurons.", "url": "https://disease-ontology.org/term/DOID:1289", "evidence": [ { "id": "1289", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1289" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YBG5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YBG5" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YBG5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YBG5" } ], "pmid": "" }, { "name": "L-leucine binding", "id": "GO:0070728", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070728", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YBG5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YBG5" } ], "pmid": "" }, { "name": "histone H2A ubiquitin ligase activity", "id": "GO:0141053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141053", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YBG5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YBG5" } ], "pmid": "" } ], "biological_process": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YBG5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YBG5" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process via the N-end rule pathway", "id": "GO:0071596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071596", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YBG5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YBG5" } ], "pmid": "" }, { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YBG5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YBG5" } ], "pmid": "" }, { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YBG5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YBG5" } ], "pmid": "" }, { "name": "positive regulation of T cell receptor signaling pathway", "id": "GO:0050862", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050862", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YBG5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YBG5" } ], "pmid": "" }, { "name": "negative regulation of TOR signaling", "id": "GO:0032007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032007", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YBG5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YBG5" } ], "pmid": "" }, { "name": "male meiotic nuclear division", "id": "GO:0007140", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007140", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YBG5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YBG5" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YBG5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YBG5" } ], "pmid": "" }, { "name": "protein K63-linked ubiquitination", "id": "GO:0070534", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070534", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YBG5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YBG5" } ], "pmid": "" }, { "name": "reciprocal meiotic recombination", "id": "GO:0007131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007131", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YBG5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YBG5" } ], "pmid": "" }, { "name": "heterochromatin formation", "id": "GO:0031507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031507", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YBG5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YBG5" } ], "pmid": "" }, { "name": "male meiosis I", "id": "GO:0007141", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007141", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YBG5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YBG5" } ], "pmid": "" }, { "name": "cellular response to L-leucine", "id": "GO:0071233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071233", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YBG5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YBG5" } ], "pmid": "" }, { "name": "transposable element silencing", "id": "GO:0010526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010526", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YBG5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YBG5" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YBG5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YBG5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YBG5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YBG5" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YBG5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YBG5" } ], "pmid": "" }, { "name": "ubiquitin ligase complex", "id": "GO:0000151", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000151", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YBG5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YBG5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5YBG5-1" }, { "uniprot_canonical_ac": "A0A8I6A346-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A346", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A346" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 312, "chemical_mass": 34978.0, "gene_names": "Olr1177;Or7e173d;Olr1177;Or7e173", "protein_name": "", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A346", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A346" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A346", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A346" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A346", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A346" } ], "pmid": "" } ], "biological_process": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A346", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A346" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6A346-1" }, { "uniprot_canonical_ac": "A0A8I6A588-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A588", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A588" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 254, "chemical_mass": 30030.0, "gene_names": "Elf5;Elf5", "protein_name": "ETS-related transcription factor Elf-5", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A588", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A588" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A588", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A588" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A588", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A588" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A588", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A588" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A588", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A588" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A588", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A588" } ], "pmid": "" }, { "name": "ectoderm development", "id": "GO:0007398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007398", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A588", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A588" } ], "pmid": "" }, { "name": "mammary gland epithelial cell differentiation", "id": "GO:0060644", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060644", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A588", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A588" } ], "pmid": "" }, { "name": "negative regulation of cell differentiation", "id": "GO:0045596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045596", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A588", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A588" } ], "pmid": "" }, { "name": "somatic stem cell population maintenance", "id": "GO:0035019", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035019", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A588", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A588" } ], "pmid": "" }, { "name": "ectodermal cell fate commitment", "id": "GO:0001712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001712", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A588", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A588" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A588", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A588" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A588", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A588" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A588", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A588" } ], "pmid": "" }, { "name": "sequence-specific double-stranded DNA binding", "id": "GO:1990837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990837", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A588", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A588" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A588", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A588" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A588", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A588" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6A588-1" }, { "uniprot_canonical_ac": "A0A8I5YBL2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YBL2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YBL2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 913, "chemical_mass": 103660.0, "gene_names": "Ptpn3;Ptpn3", "protein_name": "Tyrosine-protein phosphatase non-receptor type", "disease": [], "cellular_component": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YBL2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YBL2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YBL2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YBL2" } ], "pmid": "" }, { "name": "cytoplasmic side of plasma membrane", "id": "GO:0009898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009898", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YBL2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YBL2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YBL2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YBL2" } ], "pmid": "" } ], "molecular_function": [ { "name": "cytoskeletal protein binding", "id": "GO:0008092", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008092", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YBL2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YBL2" } ], "pmid": "" }, { "name": "protein tyrosine phosphatase activity", "id": "GO:0004725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004725", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YBL2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YBL2" } ], "pmid": "" }, { "name": "phosphotyrosine residue binding", "id": "GO:0001784", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001784", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YBL2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YBL2" } ], "pmid": "" }, { "name": "ATPase binding", "id": "GO:0051117", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051117", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YBL2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YBL2" } ], "pmid": "" }, { "name": "sodium channel regulator activity", "id": "GO:0017080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017080", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YBL2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YBL2" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of membrane protein ectodomain proteolysis", "id": "GO:0051045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051045", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YBL2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YBL2" } ], "pmid": "" }, { "name": "negative regulation of mitotic cell cycle", "id": "GO:0045930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045930", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YBL2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YBL2" } ], "pmid": "" }, { "name": "liver regeneration", "id": "GO:0097421", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097421", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YBL2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YBL2" } ], "pmid": "" }, { "name": "regulation of membrane depolarization during action potential", "id": "GO:0098902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098902", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YBL2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YBL2" } ], "pmid": "" }, { "name": "regulation of sodium ion transmembrane transport", "id": "GO:1902305", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902305", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YBL2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YBL2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5YBL2-1" }, { "uniprot_canonical_ac": "A0A0G2JUW3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JUW3", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JUW3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 574, "chemical_mass": 64318.0, "gene_names": "Crispld2", "protein_name": "", "disease": [ { "disease_id": "DOID:0050567", "name": "orofacial cleft", "description": "A physical disorder that is characterized by cleft lip and/or cleft palate that result in feeding, speech and hearing problems caused by failures during development.", "url": "https://disease-ontology.org/term/DOID:0050567", "evidence": [ { "id": "0050567", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050567" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JUW3", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JUW3" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JUW3", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JUW3" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JUW3", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JUW3" } ], "pmid": "" }, { "name": "transport vesicle", "id": "GO:0030133", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030133", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JUW3", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JUW3" } ], "pmid": "" } ], "molecular_function": [ { "name": "heparin binding", "id": "GO:0008201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008201", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JUW3", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JUW3" } ], "pmid": "" }, { "name": "glycosaminoglycan binding", "id": "GO:0005539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005539", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JUW3", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JUW3" } ], "pmid": "" } ], "biological_process": [ { "name": "extracellular matrix organization", "id": "GO:0030198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030198", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JUW3", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JUW3" } ], "pmid": "" }, { "name": "lung development", "id": "GO:0030324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030324", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JUW3", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JUW3" } ], "pmid": "" }, { "name": "face morphogenesis", "id": "GO:0060325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060325", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JUW3", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JUW3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A0G2JUW3-1", "start_pos": "62", "end_pos": "62", "site_lbl": "Thr62", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 62, "start_aa": "Thr", "end_pos": 62, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr62", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A0G2JUW3-1", "start_pos": "106", "end_pos": "106", "site_lbl": "Met106", "weight": 0.0, "snv": [ { "sequence_org": "M", "sequence_mut": "T", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (NTM->NTT).", "chr_id": "19", "chr_pos": "64979110", "evidence": [ { "id": "rs3323308644", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3323308644" } ] } ] } ], "record_id": "A0A0G2JUW3-1" }, { "uniprot_canonical_ac": "A0A8I5ZUE2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUE2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUE2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1515, "chemical_mass": 165206.0, "gene_names": "Arhgef40", "protein_name": "", "disease": [], "molecular_function": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUE2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUE2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I5ZUE2-1", "start_pos": "1488", "end_pos": "1488", "site_lbl": "Thr1488", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1488, "start_aa": "Thr", "end_pos": 1488, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1488", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I5ZUE2-1" }, { "uniprot_canonical_ac": "A0A8I6ACB1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACB1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACB1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1224, "chemical_mass": 135771.0, "gene_names": "Wdr11", "protein_name": "WD repeat-containing protein 11", "disease": [ { "disease_id": "DOID:0060308", "name": "autosomal recessive intellectual developmental disorder", "description": "A intellectual disability characterized by an autosomal recessive inheritance pattern.", "url": "https://disease-ontology.org/term/DOID:0060308", "evidence": [ { "id": "0060308", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060308" } ], "weight": 0.0 }, { "disease_id": "DOID:0060340", "name": "ciliopathy", "description": "A syndrome associated with mutations encoding defective proteins, which result in either abnormal function formation or function of cilia.", "url": "https://disease-ontology.org/term/DOID:0060340", "evidence": [ { "id": "0060340", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060340" } ], "weight": 0.0 }, { "disease_id": "DOID:0090087", "name": "hypogonadotropic hypogonadism 14 with or without anosmia", "description": "A hypogonadotropic hypogonadism that has_material_basis_in heterozygous mutation in the WDR11 gene on chromosome 10q26.", "url": "https://disease-ontology.org/term/DOID:0090087", "evidence": [ { "id": "0090087", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0090087" } ], "weight": 0.0 }, { "disease_id": "DOID:3614", "name": "Kallmann syndrome", "description": "A hypogonadotropic hypogonadism with a defective sense of smell (anosmia or hyposmia).", "url": "https://disease-ontology.org/term/DOID:3614", "evidence": [ { "id": "3614", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3614" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACB1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACB1" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACB1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACB1" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACB1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACB1" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACB1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACB1" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACB1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACB1" } ], "pmid": "" }, { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACB1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACB1" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACB1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACB1" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACB1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACB1" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACB1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACB1" } ], "pmid": "" }, { "name": "heart development", "id": "GO:0007507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007507", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACB1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACB1" } ], "pmid": "" }, { "name": "multicellular organism growth", "id": "GO:0035264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035264", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACB1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACB1" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACB1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACB1" } ], "pmid": "" }, { "name": "regulation of smoothened signaling pathway", "id": "GO:0008589", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008589", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACB1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACB1" } ], "pmid": "" }, { "name": "head development", "id": "GO:0060322", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060322", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACB1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACB1" } ], "pmid": "" }, { "name": "vesicle tethering to Golgi", "id": "GO:0099041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099041", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACB1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACB1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6ACB1-1" }, { "uniprot_canonical_ac": "A0A8I5ZJ94-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZJ94", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZJ94" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1908, "chemical_mass": 209489.0, "gene_names": "Ank1", "protein_name": "Ankyrin-1", "disease": [ { "disease_id": "DOID:0110916", "name": "hereditary spherocytosis type 1", "description": "A hereditary spherocytosis that has_material_basis_in an autosomal dominant mutation of the ANK1 gene on chromosome 8p11.21.", "url": "https://disease-ontology.org/term/DOID:0110916", "evidence": [ { "id": "0110916", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110916" } ], "weight": 0.0 }, { "disease_id": "DOID:12365", "name": "malaria", "description": "A parasitic protozoa infectious disease characterized as a vector-borne infectious disease caused by the presence of protozoan parasites of the genus Plasmodium in the red blood cells, transmitted from an infected to an uninfected individual by the bite of anopheline mosquitoes, and characterized by periodic attacks of chills and fever that coincide with mass destruction of blood cells and the release of toxic substances by the parasite at the end of each reproductive cycle.", "url": "https://disease-ontology.org/term/DOID:12365", "evidence": [ { "id": "12365", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12365" } ], "weight": 0.0 }, { "disease_id": "DOID:12971", "name": "hereditary spherocytosis", "description": "A congenital hemolytic anemia characterized by the production of red blood cells with a sphere shape, rather than the normal biconcave disk shape.", "url": "https://disease-ontology.org/term/DOID:12971", "evidence": [ { "id": "12971", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12971" } ], "weight": 0.0 }, { "disease_id": "DOID:224", "name": "transient cerebral ischemia", "description": "A brain ischemia that is characterized by ischemia of brief duration and without resultant tissue death.", "url": "https://disease-ontology.org/term/DOID:224", "evidence": [ { "id": "224", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:224" } ], "weight": 0.0 }, { "disease_id": "DOID:2355", "name": "anemia", "description": "A hematopoietic system disease that is characterized by a decrease in the normal number of red blood cells.", "url": "https://disease-ontology.org/term/DOID:2355", "evidence": [ { "id": "2355", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2355" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZJ94", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZJ94" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZJ94", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZJ94" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZJ94", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZJ94" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZJ94", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZJ94" } ], "pmid": "" }, { "name": "postsynaptic membrane", "id": "GO:0045211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045211", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZJ94", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZJ94" } ], "pmid": "" }, { "name": "axolemma", "id": "GO:0030673", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030673", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZJ94", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZJ94" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZJ94", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZJ94" } ], "pmid": "" }, { "name": "sarcolemma", "id": "GO:0042383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042383", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZJ94", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZJ94" } ], "pmid": "" }, { "name": "cytoplasmic side of plasma membrane", "id": "GO:0009898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009898", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZJ94", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZJ94" } ], "pmid": "" }, { "name": "spectrin-associated cytoskeleton", "id": "GO:0014731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014731", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZJ94", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZJ94" } ], "pmid": "" }, { "name": "Z disc", "id": "GO:0030018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030018", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZJ94", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZJ94" } ], "pmid": "" }, { "name": "cortical cytoskeleton", "id": "GO:0030863", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030863", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZJ94", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZJ94" } ], "pmid": "" }, { "name": "M band", "id": "GO:0031430", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031430", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZJ94", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZJ94" } ], "pmid": "" }, { "name": "sarcoplasmic reticulum", "id": "GO:0016529", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016529", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZJ94", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZJ94" } ], "pmid": "" }, { "name": "A band", "id": "GO:0031672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031672", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZJ94", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZJ94" } ], "pmid": "" }, { "name": "ankyrin-1 complex", "id": "GO:0170014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0170014", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZJ94", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZJ94" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZJ94", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZJ94" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZJ94", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZJ94" } ], "pmid": "" } ], "biological_process": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZJ94", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZJ94" } ], "pmid": "" }, { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZJ94", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZJ94" } ], "pmid": "" }, { "name": "protein localization to plasma membrane", "id": "GO:0072659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072659", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZJ94", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZJ94" } ], "pmid": "" }, { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZJ94", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZJ94" } ], "pmid": "" }, { "name": "porphyrin-containing compound biosynthetic process", "id": "GO:0006779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006779", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZJ94", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZJ94" } ], "pmid": "" }, { "name": "erythrocyte development", "id": "GO:0048821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048821", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZJ94", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZJ94" } ], "pmid": "" }, { "name": "multicellular organismal-level iron ion homeostasis", "id": "GO:0060586", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060586", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZJ94", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZJ94" } ], "pmid": "" } ], "molecular_function": [ { "name": "enzyme binding", "id": "GO:0019899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019899", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZJ94", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZJ94" } ], "pmid": "" }, { "name": "ATPase binding", "id": "GO:0051117", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051117", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZJ94", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZJ94" } ], "pmid": "" }, { "name": "transmembrane transporter binding", "id": "GO:0044325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044325", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZJ94", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZJ94" } ], "pmid": "" }, { "name": "spectrin binding", "id": "GO:0030507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030507", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZJ94", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZJ94" } ], "pmid": "" }, { "name": "cytoskeletal anchor activity", "id": "GO:0008093", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008093", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZJ94", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZJ94" } ], "pmid": "" }, { "name": "protein phosphatase binding", "id": "GO:0019903", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019903", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZJ94", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZJ94" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I5ZJ94-1", "start_pos": "1022", "end_pos": "1022", "site_lbl": "Thr1022", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1022, "start_aa": "Thr", "end_pos": 1022, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1022", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I5ZJ94-1" }, { "uniprot_canonical_ac": "A0A8I5ZQZ7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQZ7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 612, "chemical_mass": 71502.0, "gene_names": "Zfp655;RGD1309158;Zfp655;Znf655", "protein_name": "", "disease": [], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQZ7" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQZ7" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQZ7" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQZ7" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQZ7" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQZ7" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQZ7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQZ7" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQZ7" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQZ7" } ], "pmid": "" }, { "name": "negative regulation of G1/S transition of mitotic cell cycle", "id": "GO:2000134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000134", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQZ7" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQZ7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZQZ7-1" }, { "uniprot_canonical_ac": "A0A8I6GGK1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GGK1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GGK1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 395, "chemical_mass": 44550.0, "gene_names": "Chst6;Chst5;Chst6;RGD1561144", "protein_name": "Sulfotransferase", "disease": [ { "disease_id": "DOID:2565", "name": "macular corneal dystrophy", "description": "A corneal dystrophy that is characterized by corneal haze, bilateral loss of vision, eventually necessitating corneal transplantation resulting from progressive punctate opacities in the cornea.", "url": "https://disease-ontology.org/term/DOID:2565", "evidence": [ { "id": "2565", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2565" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "N-acetylglucosamine 6-O-sulfotransferase activity", "id": "GO:0001517", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001517", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GGK1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GGK1" } ], "pmid": "" }, { "name": "keratan sulfotransferase activity", "id": "GO:0045130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045130", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GGK1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GGK1" } ], "pmid": "" } ], "biological_process": [ { "name": "N-acetylglucosamine metabolic process", "id": "GO:0006044", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006044", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GGK1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GGK1" } ], "pmid": "" }, { "name": "carbohydrate metabolic process", "id": "GO:0005975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005975", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GGK1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GGK1" } ], "pmid": "" }, { "name": "sulfur compound metabolic process", "id": "GO:0006790", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006790", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GGK1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GGK1" } ], "pmid": "" }, { "name": "keratan sulfate proteoglycan biosynthetic process", "id": "GO:0018146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018146", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GGK1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GGK1" } ], "pmid": "" } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GGK1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GGK1" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GGK1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GGK1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6GGK1-1" }, { "uniprot_canonical_ac": "A0A8I5Y2C3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y2C3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y2C3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 978, "chemical_mass": 103955.0, "gene_names": "Mrtfa;Mkl1", "protein_name": "", "disease": [ { "disease_id": "DOID:0111998", "name": "immunodeficiency 66", "description": "A primary immunodeficiency disease characterized by onset in infancy of recurrent bacterial infections and defective immune cell migration and chemotaxis primarily in neutrophils although other cell types may also be affected that has_material_basis_in homozygous or compound heterozygous mutation in the MKL1 gene on chromosome 22q13.1-q13.2.", "url": "https://disease-ontology.org/term/DOID:0111998", "evidence": [ { "id": "0111998", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111998" } ], "weight": 0.0 }, { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:224", "name": "transient cerebral ischemia", "description": "A brain ischemia that is characterized by ischemia of brief duration and without resultant tissue death.", "url": "https://disease-ontology.org/term/DOID:224", "evidence": [ { "id": "224", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:224" } ], "weight": 0.0 }, { "disease_id": "DOID:8761", "name": "acute megakaryocytic leukemia", "description": "An acute myeloid leukemia that derives from blood-forming tissue in which megakaryocytes proliferate in the bone marrow and circulate in the blood in large numbers.", "url": "https://disease-ontology.org/term/DOID:8761", "evidence": [ { "id": "8761", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8761" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y2C3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y2C3" } ], "pmid": "" }, { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y2C3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y2C3" } ], "pmid": "" }, { "name": "actin monomer binding", "id": "GO:0003785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003785", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y2C3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y2C3" } ], "pmid": "" }, { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y2C3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y2C3" } ], "pmid": "" }, { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y2C3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y2C3" } ], "pmid": "" }, { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y2C3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y2C3" } ], "pmid": "" }, { "name": "leucine zipper domain binding", "id": "GO:0043522", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043522", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y2C3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y2C3" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y2C3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y2C3" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y2C3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y2C3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y2C3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y2C3" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y2C3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y2C3" } ], "pmid": "" }, { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y2C3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y2C3" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y2C3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y2C3" } ], "pmid": "" }, { "name": "postsynapse", "id": "GO:0098794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098794", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y2C3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y2C3" } ], "pmid": "" }, { "name": "presynapse", "id": "GO:0098793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098793", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y2C3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y2C3" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y2C3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y2C3" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y2C3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y2C3" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y2C3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y2C3" } ], "pmid": "" }, { "name": "smooth muscle cell differentiation", "id": "GO:0051145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051145", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y2C3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y2C3" } ], "pmid": "" }, { "name": "cellular response to angiotensin", "id": "GO:1904385", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904385", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y2C3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y2C3" } ], "pmid": "" }, { "name": "positive regulation of hepatic stellate cell activation", "id": "GO:2000491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000491", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y2C3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y2C3" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y2C3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y2C3" } ], "pmid": "" }, { "name": "forebrain development", "id": "GO:0030900", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030900", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y2C3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y2C3" } ], "pmid": "" }, { "name": "neuron projection development", "id": "GO:0031175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031175", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y2C3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y2C3" } ], "pmid": "" }, { "name": "positive regulation of neuron differentiation", "id": "GO:0045666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045666", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y2C3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y2C3" } ], "pmid": "" }, { "name": "cellular response to retinoic acid", "id": "GO:0071300", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071300", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y2C3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y2C3" } ], "pmid": "" }, { "name": "neuron migration", "id": "GO:0001764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001764", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y2C3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y2C3" } ], "pmid": "" }, { "name": "response to amyloid-beta", "id": "GO:1904645", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904645", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y2C3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y2C3" } ], "pmid": "" }, { "name": "negative regulation of neuron apoptotic process", "id": "GO:0043524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043524", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y2C3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y2C3" } ], "pmid": "" }, { "name": "positive regulation of collagen biosynthetic process", "id": "GO:0032967", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032967", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y2C3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y2C3" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y2C3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y2C3" } ], "pmid": "" }, { "name": "positive regulation of endothelial cell differentiation", "id": "GO:0045603", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045603", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y2C3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y2C3" } ], "pmid": "" }, { "name": "cellular response to transforming growth factor beta stimulus", "id": "GO:0071560", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071560", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y2C3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y2C3" } ], "pmid": "" }, { "name": "positive regulation of actin filament polymerization", "id": "GO:0030838", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030838", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y2C3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y2C3" } ], "pmid": "" }, { "name": "positive regulation of cardiac muscle hypertrophy", "id": "GO:0010613", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010613", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y2C3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y2C3" } ], "pmid": "" }, { "name": "negative regulation of cardiac muscle cell apoptotic process", "id": "GO:0010667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010667", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y2C3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y2C3" } ], "pmid": "" }, { "name": "negative regulation of apoptotic signaling pathway", "id": "GO:2001234", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001234", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y2C3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y2C3" } ], "pmid": "" }, { "name": "positive regulation of miRNA transcription", "id": "GO:1902895", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902895", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y2C3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y2C3" } ], "pmid": "" }, { "name": "wound healing, spreading of cells", "id": "GO:0044319", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044319", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y2C3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y2C3" } ], "pmid": "" }, { "name": "positive regulation of hepatic stellate cell proliferation", "id": "GO:1904899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904899", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y2C3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y2C3" } ], "pmid": "" }, { "name": "regulation of modification of postsynaptic structure", "id": "GO:0099159", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099159", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y2C3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y2C3" } ], "pmid": "" }, { "name": "positive regulation of hepatic stellate cell migration", "id": "GO:0061870", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061870", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y2C3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y2C3" } ], "pmid": "" }, { "name": "positive regulation of hepatic stellate cell contraction", "id": "GO:0061874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061874", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y2C3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y2C3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I5Y2C3-1", "start_pos": "360", "end_pos": "360", "site_lbl": "Thr360", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 360, "start_aa": "Thr", "end_pos": 360, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr360", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I5Y2C3-1", "start_pos": "375", "end_pos": "375", "site_lbl": "Thr375", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 375, "start_aa": "Thr", "end_pos": 375, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr375", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I5Y2C3-1", "start_pos": "509", "end_pos": "509", "site_lbl": "Thr509", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 509, "start_aa": "Thr", "end_pos": 509, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr509", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I5Y2C3-1" }, { "uniprot_canonical_ac": "A0A8I6A2B1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2B1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2B1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1423, "chemical_mass": 157692.0, "gene_names": "Carmil1;Carmil1;Lrrc16a;Lrrc16", "protein_name": "", "disease": [], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2B1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2B1" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2B1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2B1" } ], "pmid": "" }, { "name": "lamellipodium", "id": "GO:0030027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030027", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2B1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2B1" } ], "pmid": "" }, { "name": "cell leading edge", "id": "GO:0031252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031252", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2B1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2B1" } ], "pmid": "" }, { "name": "macropinosome", "id": "GO:0044354", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044354", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2B1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2B1" } ], "pmid": "" }, { "name": "filamentous actin", "id": "GO:0031941", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031941", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2B1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2B1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2B1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2B1" } ], "pmid": "" } ], "biological_process": [ { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2B1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2B1" } ], "pmid": "" }, { "name": "positive regulation of cell migration", "id": "GO:0030335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030335", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2B1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2B1" } ], "pmid": "" }, { "name": "urate metabolic process", "id": "GO:0046415", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046415", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2B1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2B1" } ], "pmid": "" }, { "name": "positive regulation of stress fiber assembly", "id": "GO:0051496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051496", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2B1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2B1" } ], "pmid": "" }, { "name": "lamellipodium assembly", "id": "GO:0030032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030032", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2B1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2B1" } ], "pmid": "" }, { "name": "positive regulation of substrate adhesion-dependent cell spreading", "id": "GO:1900026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900026", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2B1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2B1" } ], "pmid": "" }, { "name": "ruffle organization", "id": "GO:0031529", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031529", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2B1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2B1" } ], "pmid": "" }, { "name": "regulation of Arp2/3 complex-mediated actin nucleation", "id": "GO:0034315", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034315", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2B1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2B1" } ], "pmid": "" }, { "name": "actin filament network formation", "id": "GO:0051639", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051639", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2B1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2B1" } ], "pmid": "" }, { "name": "positive regulation of actin filament polymerization", "id": "GO:0030838", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030838", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2B1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2B1" } ], "pmid": "" }, { "name": "macropinocytosis", "id": "GO:0044351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044351", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2B1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2B1" } ], "pmid": "" }, { "name": "barbed-end actin filament uncapping", "id": "GO:0051638", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051638", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2B1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2B1" } ], "pmid": "" }, { "name": "positive regulation of lamellipodium organization", "id": "GO:1902745", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902745", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2B1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2B1" } ], "pmid": "" }, { "name": "negative regulation of barbed-end actin filament capping", "id": "GO:2000813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000813", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2B1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2B1" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-containing complex binding", "id": "GO:0044877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044877", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2B1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2B1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6A2B1-1" }, { "uniprot_canonical_ac": "A0A8I6AMA8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AMA8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AMA8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1102, "chemical_mass": 122569.0, "gene_names": "Smarcc1;Smarcc1", "protein_name": "", "disease": [ { "disease_id": "DOID:0050340", "name": "opportunistic bacterial infectious disease", "description": "A bacterial infectious disease that results_in infection by bacteria in individuals whose host defense mechanisms have been compromised.", "url": "https://disease-ontology.org/term/DOID:0050340", "evidence": [ { "id": "0050340", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050340" } ], "weight": 0.0 }, { "disease_id": "DOID:0080199", "name": "colorectal carcinoma", "description": "A colorectal cancer that arises from the colon or rectum and invades through the muscularis mucosa into the submucosa.", "url": "https://disease-ontology.org/term/DOID:0080199", "evidence": [ { "id": "0080199", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080199" } ], "weight": 0.0 }, { "disease_id": "DOID:10908", "name": "hydrocephalus", "description": "A cerebral degeneration characterized by an abnormal accumulation of cerebrospinal fluid in the ventricles of the brain, leading to progressive enlargement of the head.", "url": "https://disease-ontology.org/term/DOID:10908", "evidence": [ { "id": "10908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10908" } ], "weight": 0.0 }, { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 }, { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 }, { "disease_id": "DOID:1925", "name": "Coffin-Siris syndrome", "description": "An autosomal dominant intellectual developmental disorder that is characterized by mental retardation associated with coarse facial features, hypertrichosis, sparse scalp hair, and hypoplastic or absent fifth fingernails or toenails.", "url": "https://disease-ontology.org/term/DOID:1925", "evidence": [ { "id": "1925", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1925" } ], "weight": 0.0 }, { "disease_id": "DOID:4450", "name": "renal cell carcinoma", "description": "A renal carcinoma that has_material_basis_in the lining of the proximal convoluted renal tubule of the kidney.", "url": "https://disease-ontology.org/term/DOID:4450", "evidence": [ { "id": "4450", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4450" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nuclear lumen", "id": "GO:0031981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031981", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AMA8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AMA8" } ], "pmid": "" }, { "name": "SWI/SNF complex", "id": "GO:0016514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016514", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AMA8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AMA8" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AMA8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AMA8" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AMA8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AMA8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AMA8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AMA8" } ], "pmid": "" }, { "name": "npBAF complex", "id": "GO:0071564", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071564", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AMA8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AMA8" } ], "pmid": "" }, { "name": "nBAF complex", "id": "GO:0071565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071565", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AMA8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AMA8" } ], "pmid": "" }, { "name": "XY body", "id": "GO:0001741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001741", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AMA8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AMA8" } ], "pmid": "" } ], "molecular_function": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AMA8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AMA8" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AMA8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AMA8" } ], "pmid": "" } ], "biological_process": [ { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AMA8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AMA8" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AMA8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AMA8" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AMA8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AMA8" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AMA8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AMA8" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AMA8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AMA8" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AMA8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AMA8" } ], "pmid": "" }, { "name": "animal organ morphogenesis", "id": "GO:0009887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009887", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AMA8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AMA8" } ], "pmid": "" }, { "name": "insulin receptor signaling pathway", "id": "GO:0008286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008286", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AMA8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AMA8" } ], "pmid": "" }, { "name": "prostate gland development", "id": "GO:0030850", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030850", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AMA8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AMA8" } ], "pmid": "" }, { "name": "nucleosome disassembly", "id": "GO:0006337", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006337", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AMA8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AMA8" } ], "pmid": "" }, { "name": "negative regulation of proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0032435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032435", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AMA8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AMA8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6AMA8-1", "start_pos": "1048", "end_pos": "1048", "site_lbl": "Thr1048", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1048, "start_aa": "Thr", "end_pos": 1048, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1048", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I6AMA8-1", "start_pos": "1101", "end_pos": "1101", "site_lbl": "Thr1101", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1101, "start_aa": "Thr", "end_pos": 1101, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1101", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I6AMA8-1", "start_pos": "334", "end_pos": "334", "site_lbl": "Thr334", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 334, "start_aa": "Thr", "end_pos": 334, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr334", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I6AMA8-1", "start_pos": "552", "end_pos": "552", "site_lbl": "Thr552", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 552, "start_aa": "Thr", "end_pos": 552, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr552", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6AMA8-1" }, { "uniprot_canonical_ac": "B1WC44-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "B1WC44", "url": "https://www.uniprot.org/uniprotkb/B1WC44" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 503, "chemical_mass": 57720.0, "gene_names": "Nmd3;Nmd3;RGD1308468", "protein_name": "60S ribosomal export protein NMD3", "disease": [], "biological_process": [ { "name": "ribosomal large subunit export from nucleus", "id": "GO:0000055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000055", "evidence": [ { "database": "UniProtKB", "id": "B1WC44", "url": "https://www.uniprot.org/uniprotkb/B1WC44" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "B1WC44", "url": "https://www.uniprot.org/uniprotkb/B1WC44" } ], "pmid": "" }, { "name": "positive regulation of RNA biosynthetic process", "id": "GO:1902680", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902680", "evidence": [ { "database": "UniProtKB", "id": "B1WC44", "url": "https://www.uniprot.org/uniprotkb/B1WC44" } ], "pmid": "" }, { "name": "positive regulation of protein localization to nucleolus", "id": "GO:1904751", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904751", "evidence": [ { "database": "UniProtKB", "id": "B1WC44", "url": "https://www.uniprot.org/uniprotkb/B1WC44" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "B1WC44", "url": "https://www.uniprot.org/uniprotkb/B1WC44" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "B1WC44", "url": "https://www.uniprot.org/uniprotkb/B1WC44" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "B1WC44", "url": "https://www.uniprot.org/uniprotkb/B1WC44" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "B1WC44", "url": "https://www.uniprot.org/uniprotkb/B1WC44" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "B1WC44", "url": "https://www.uniprot.org/uniprotkb/B1WC44" } ], "pmid": "" }, { "name": "ribosomal large subunit binding", "id": "GO:0043023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043023", "evidence": [ { "database": "UniProtKB", "id": "B1WC44", "url": "https://www.uniprot.org/uniprotkb/B1WC44" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "B1WC44-1" }, { "uniprot_canonical_ac": "A0A8I5ZRQ2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZRQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZRQ2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 873, "chemical_mass": 94282.0, "gene_names": "Shroom1", "protein_name": "", "disease": [], "cellular_component": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZRQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZRQ2" } ], "pmid": "" }, { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZRQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZRQ2" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZRQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZRQ2" } ], "pmid": "" }, { "name": "cortical actin cytoskeleton", "id": "GO:0030864", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030864", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZRQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZRQ2" } ], "pmid": "" }, { "name": "apical junction complex", "id": "GO:0043296", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043296", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZRQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZRQ2" } ], "pmid": "" } ], "molecular_function": [ { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZRQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZRQ2" } ], "pmid": "" }, { "name": "myosin II binding", "id": "GO:0045159", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045159", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZRQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZRQ2" } ], "pmid": "" } ], "biological_process": [ { "name": "cell morphogenesis", "id": "GO:0000902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000902", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZRQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZRQ2" } ], "pmid": "" }, { "name": "actin filament bundle assembly", "id": "GO:0051017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051017", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZRQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZRQ2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I5ZRQ2-1", "start_pos": "25", "end_pos": "25", "site_lbl": "Thr25", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 25, "start_aa": "Thr", "end_pos": 25, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr25", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I5ZRQ2-1", "start_pos": "273", "end_pos": "273", "site_lbl": "Thr273", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 273, "start_aa": "Thr", "end_pos": 273, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr273", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I5ZRQ2-1" }, { "uniprot_canonical_ac": "A0A8I5Y5Q0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y5Q0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y5Q0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1093, "chemical_mass": 125093.0, "gene_names": "Phkb;Phkb", "protein_name": "Phosphorylase b kinase regulatory subunit", "disease": [ { "disease_id": "DOID:0111041", "name": "glycogen storage disease IXb", "description": "A glycogen storage disease IX characterized by autosomal recessive inheritance of hepatomegaly, short stature, hypotonia and accumulation of glycogen in both liver and muscle, without clinical symptoms, that has_material_basis_in compound heterozygous mutation in the PHKB gene on chromosome 16q12.", "url": "https://disease-ontology.org/term/DOID:0111041", "evidence": [ { "id": "0111041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111041" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y5Q0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y5Q0" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y5Q0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y5Q0" } ], "pmid": "" }, { "name": "phosphorylase kinase complex", "id": "GO:0005964", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005964", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y5Q0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y5Q0" } ], "pmid": "" } ], "biological_process": [ { "name": "glycogen metabolic process", "id": "GO:0005977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005977", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y5Q0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y5Q0" } ], "pmid": "" }, { "name": "positive regulation of glycogen catabolic process", "id": "GO:0045819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045819", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y5Q0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y5Q0" } ], "pmid": "" }, { "name": "protein phosphorylation", "id": "GO:0006468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006468", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y5Q0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y5Q0" } ], "pmid": "" }, { "name": "glucose homeostasis", "id": "GO:0042593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042593", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y5Q0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y5Q0" } ], "pmid": "" }, { "name": "glycogen catabolic process", "id": "GO:0005980", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005980", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y5Q0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y5Q0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5Y5Q0-1" }, { "uniprot_canonical_ac": "A0A8I5ZSJ9-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZSJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZSJ9" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 862, "chemical_mass": 96130.0, "gene_names": "Afap1l2", "protein_name": "Actin filament-associated protein 1-like 2", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZSJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZSJ9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZSJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZSJ9" } ], "pmid": "" } ], "biological_process": [ { "name": "inflammatory response", "id": "GO:0006954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006954", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZSJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZSJ9" } ], "pmid": "" }, { "name": "regulation of mitotic cell cycle", "id": "GO:0007346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007346", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZSJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZSJ9" } ], "pmid": "" }, { "name": "regulation of interleukin-6 production", "id": "GO:0032675", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032675", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZSJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZSJ9" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZSJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZSJ9" } ], "pmid": "" }, { "name": "positive regulation of epidermal growth factor receptor signaling pathway", "id": "GO:0045742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045742", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZSJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZSJ9" } ], "pmid": "" }, { "name": "positive regulation of interleukin-8 production", "id": "GO:0032757", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032757", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZSJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZSJ9" } ], "pmid": "" } ], "molecular_function": [ { "name": "SH3 domain binding", "id": "GO:0017124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017124", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZSJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZSJ9" } ], "pmid": "" }, { "name": "SH2 domain binding", "id": "GO:0042169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042169", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZSJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZSJ9" } ], "pmid": "" }, { "name": "protein tyrosine kinase activator activity", "id": "GO:0030296", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030296", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZSJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZSJ9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I5ZSJ9-1", "start_pos": "559", "end_pos": "559", "site_lbl": "Thr559", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 559, "start_aa": "Thr", "end_pos": 559, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr559", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I5ZSJ9-1", "start_pos": "649", "end_pos": "649", "site_lbl": "Thr649", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 649, "start_aa": "Thr", "end_pos": 649, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr649", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I5ZSJ9-1" }, { "uniprot_canonical_ac": "A0A8J8XSR6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8J8XSR6", "url": "https://www.uniprot.org/uniprotkb/A0A8J8XSR6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 348, "chemical_mass": 37449.0, "gene_names": "Lysmd2", "protein_name": "LysM and putative peptidoglycan-binding domain-containing protein 2", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8J8XSR6-1" }, { "uniprot_canonical_ac": "A0A8I5XW36-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XW36", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XW36" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 395, "chemical_mass": 44122.0, "gene_names": "Wtap;RGD1563824;Wtap", "protein_name": "Pre-mRNA-splicing regulator WTAP", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XW36", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XW36" } ], "pmid": "" }, { "name": "RNA N6-methyladenosine methyltransferase complex", "id": "GO:0036396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036396", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XW36", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XW36" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XW36", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XW36" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XW36", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XW36" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XW36", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XW36" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XW36", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XW36" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XW36", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XW36" } ], "pmid": "" }, { "name": "mRNA modification", "id": "GO:0016556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016556", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XW36", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XW36" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XW36", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XW36" } ], "pmid": "" }, { "name": "regulation of alternative mRNA splicing, via spliceosome", "id": "GO:0000381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000381", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XW36", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XW36" } ], "pmid": "" } ], "molecular_function": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XW36", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XW36" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5XW36-1" }, { "uniprot_canonical_ac": "A0A8I5ZN89-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN89", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN89" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 447, "chemical_mass": 49713.0, "gene_names": "Gcdh;Gcdh", "protein_name": "Glutaryl-CoA dehydrogenase, mitochondrial", "disease": [ { "disease_id": "DOID:0111254", "name": "glutaric acidemia I", "description": "An organic acidemia characterized by impaired lysine, hydroxylysine, and tryptophan metabolism, increased urinary excretion of glutaric acid, and accumulation of 3-hydroxyglutaric and glutaric acid, resulting in striatal injury and a severe dystonic dyskinetic movement disorder that has_material_basis_in homozygous or compound heterozygous mutation in the GCDH gene on chromosome 19p13.", "url": "https://disease-ontology.org/term/DOID:0111254", "evidence": [ { "id": "0111254", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111254" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "glutaryl-CoA dehydrogenase activity", "id": "GO:0004361", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004361", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN89", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN89" } ], "pmid": "" }, { "name": "flavin adenine dinucleotide binding", "id": "GO:0050660", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050660", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN89", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN89" } ], "pmid": "" }, { "name": "fatty-acyl-CoA binding", "id": "GO:0000062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000062", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN89", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN89" } ], "pmid": "" } ], "biological_process": [ { "name": "carboxylic acid catabolic process", "id": "GO:0046395", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046395", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN89", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN89" } ], "pmid": "" }, { "name": "acyl-CoA metabolic process", "id": "GO:0006637", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006637", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN89", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN89" } ], "pmid": "" }, { "name": "L-lysine catabolic process to acetyl-CoA via saccharopine", "id": "GO:0033512", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033512", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN89", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN89" } ], "pmid": "" }, { "name": "fatty acid beta-oxidation using acyl-CoA dehydrogenase", "id": "GO:0033539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033539", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN89", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN89" } ], "pmid": "" }, { "name": "fatty-acyl-CoA biosynthetic process", "id": "GO:0046949", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046949", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN89", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN89" } ], "pmid": "" }, { "name": "fatty acid oxidation", "id": "GO:0019395", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019395", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN89", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN89" } ], "pmid": "" }, { "name": "L-lysine catabolic process to acetyl-CoA via L-pipecolate", "id": "GO:0033514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033514", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN89", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN89" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN89", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN89" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN89", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN89" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZN89-1" }, { "uniprot_canonical_ac": "A0A8I5Y768-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y768", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y768" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 547, "chemical_mass": 63047.0, "gene_names": "Zfp846;RGD1564241;Zfp426l2;Zfp846;Znf426;Znf846", "protein_name": "", "disease": [], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y768", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y768" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y768", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y768" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y768", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y768" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y768", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y768" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y768", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y768" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5Y768-1" }, { "uniprot_canonical_ac": "M0R3R8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "M0R3R8", "url": "https://www.uniprot.org/uniprotkb/M0R3R8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 662, "chemical_mass": 75231.0, "gene_names": "Eps8l3", "protein_name": "Epidermal growth factor receptor kinase substrate 8-like protein 3", "disease": [ { "disease_id": "DOID:0110702", "name": "hypotrichosis 5", "description": "A hypotrichosis that has_material_basis_in a mutation on chromosome 1p21.1-q21.3.", "url": "https://disease-ontology.org/term/DOID:0110702", "evidence": [ { "id": "0110702", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110702" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "M0R3R8", "url": "https://www.uniprot.org/uniprotkb/M0R3R8" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "M0R3R8", "url": "https://www.uniprot.org/uniprotkb/M0R3R8" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "M0R3R8", "url": "https://www.uniprot.org/uniprotkb/M0R3R8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "M0R3R8", "url": "https://www.uniprot.org/uniprotkb/M0R3R8" } ], "pmid": "" }, { "name": "ruffle membrane", "id": "GO:0032587", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032587", "evidence": [ { "database": "UniProtKB", "id": "M0R3R8", "url": "https://www.uniprot.org/uniprotkb/M0R3R8" } ], "pmid": "" } ], "biological_process": [ { "name": "Rho protein signal transduction", "id": "GO:0007266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007266", "evidence": [ { "database": "UniProtKB", "id": "M0R3R8", "url": "https://www.uniprot.org/uniprotkb/M0R3R8" } ], "pmid": "" }, { "name": "regulation of Rho protein signal transduction", "id": "GO:0035023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035023", "evidence": [ { "database": "UniProtKB", "id": "M0R3R8", "url": "https://www.uniprot.org/uniprotkb/M0R3R8" } ], "pmid": "" }, { "name": "positive regulation of ruffle assembly", "id": "GO:1900029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900029", "evidence": [ { "database": "UniProtKB", "id": "M0R3R8", "url": "https://www.uniprot.org/uniprotkb/M0R3R8" } ], "pmid": "" }, { "name": "regulation of hair cycle", "id": "GO:0042634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042634", "evidence": [ { "database": "UniProtKB", "id": "M0R3R8", "url": "https://www.uniprot.org/uniprotkb/M0R3R8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M0R3R8-1" }, { "uniprot_canonical_ac": "A0A8I6ASL4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ASL4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ASL4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 367, "chemical_mass": 41596.0, "gene_names": "Lrrc28", "protein_name": "", "disease": [], "cellular_component": [ { "name": "PML body", "id": "GO:0016605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016605", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ASL4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ASL4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6ASL4-1" }, { "uniprot_canonical_ac": "A0A8I5ZS43-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZS43", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZS43" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1865, "chemical_mass": 201339.0, "gene_names": "Casz1;Casz1;RGD1563533", "protein_name": "", "disease": [ { "disease_id": "DOID:0060410", "name": "chromosome 1p36 deletion syndrome", "description": "A chromosomal deletion syndrome that has_material_basis_in by deletion of the chromosome 1p36 region and is characterized by severe intellectual disability, a small head, deep-set eyes with straight eyebrows, midface hypoplasia, a broad, flat nose, a pointed chin and low-set ears.", "url": "https://disease-ontology.org/term/DOID:0060410", "evidence": [ { "id": "0060410", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060410" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZS43", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZS43" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZS43", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZS43" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZS43", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZS43" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZS43", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZS43" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZS43", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZS43" } ], "pmid": "" }, { "name": "negative regulation of amacrine cell differentiation", "id": "GO:1902870", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902870", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZS43", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZS43" } ], "pmid": "" }, { "name": "negative regulation of neuron differentiation", "id": "GO:0045665", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045665", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZS43", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZS43" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZS43", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZS43" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZS43", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZS43" } ], "pmid": "" }, { "name": "negative regulation of cell differentiation", "id": "GO:0045596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045596", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZS43", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZS43" } ], "pmid": "" }, { "name": "retinal rod cell fate commitment", "id": "GO:0060223", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060223", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZS43", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZS43" } ], "pmid": "" }, { "name": "negative regulation of retinal cone cell fate commitment", "id": "GO:0060226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060226", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZS43", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZS43" } ], "pmid": "" }, { "name": "retinal bipolar neuron differentiation", "id": "GO:0060040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060040", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZS43", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZS43" } ], "pmid": "" }, { "name": "regulation of neuron differentiation", "id": "GO:0045664", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045664", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZS43", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZS43" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZS43", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZS43" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZS43", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZS43" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZS43", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZS43" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I5ZS43-1", "start_pos": "103", "end_pos": "103", "site_lbl": "Thr103", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 103, "start_aa": "Thr", "end_pos": 103, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr103", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I5ZS43-1", "start_pos": "1861", "end_pos": "1861", "site_lbl": "Thr1861", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1861, "start_aa": "Thr", "end_pos": 1861, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1861", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I5ZS43-1" }, { "uniprot_canonical_ac": "A0A8I6A4J4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A4J4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A4J4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 294, "chemical_mass": 33349.0, "gene_names": "Tmem178b;Tmem178b", "protein_name": "", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A4J4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A4J4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6A4J4-1" }, { "uniprot_canonical_ac": "A0A8I6B5Y3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B5Y3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B5Y3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 591, "chemical_mass": 66276.0, "gene_names": "Nelfcd;Nelfcd", "protein_name": "", "disease": [ { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:219", "name": "colon cancer", "description": "A colorectal cancer that is located_in the colon.", "url": "https://disease-ontology.org/term/DOID:219", "evidence": [ { "id": "219", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:219" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B5Y3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B5Y3" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B5Y3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B5Y3" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B5Y3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B5Y3" } ], "pmid": "" }, { "name": "NELF complex", "id": "GO:0032021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032021", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B5Y3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B5Y3" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B5Y3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B5Y3" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B5Y3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B5Y3" } ], "pmid": "" }, { "name": "negative regulation of transcription elongation by RNA polymerase II", "id": "GO:0034244", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034244", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B5Y3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B5Y3" } ], "pmid": "" }, { "name": "transcription pausing by RNA polymerase II", "id": "GO:0160239", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160239", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B5Y3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B5Y3" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B5Y3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B5Y3" } ], "pmid": "" }, { "name": "RNA polymerase inhibitor activity", "id": "GO:0140870", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140870", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B5Y3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B5Y3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6B5Y3-1" }, { "uniprot_canonical_ac": "A0A8I5YC36-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YC36", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YC36" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 3114, "chemical_mass": 347327.0, "gene_names": "Ranbp2;LOC100911178;RGD1560047;Ranbp2", "protein_name": "E3 SUMO-protein ligase RanBP2", "disease": [ { "disease_id": "DOID:0050905", "name": "inflammatory myofibroblastic tumor", "description": "A mesenchymal cell neoplasm that has_material_basis_in myofibroblastic cells admixed with inflammatory cells.", "url": "https://disease-ontology.org/term/DOID:0050905", "evidence": [ { "id": "0050905", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050905" } ], "weight": 0.0 }, { "disease_id": "DOID:936", "name": "brain disease", "description": "A central nervous system disease that is located_in the brain.", "url": "https://disease-ontology.org/term/DOID:936", "evidence": [ { "id": "936", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:936" } ], "weight": 0.0 }, { "disease_id": "DOID:9538", "name": "multiple myeloma", "description": "A myeloid neoplasm that is located_in the plasma cells in bone marrow.", "url": "https://disease-ontology.org/term/DOID:9538", "evidence": [ { "id": "9538", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9538" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YC36", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YC36" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YC36", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YC36" } ], "pmid": "" }, { "name": "SUMO transferase activity", "id": "GO:0019789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019789", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YC36", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YC36" } ], "pmid": "" }, { "name": "peptidyl-prolyl cis-trans isomerase activity", "id": "GO:0003755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003755", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YC36", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YC36" } ], "pmid": "" }, { "name": "kinase activator activity", "id": "GO:0019209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019209", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YC36", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YC36" } ], "pmid": "" }, { "name": "SUMO ligase activity", "id": "GO:0061665", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061665", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YC36", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YC36" } ], "pmid": "" }, { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YC36", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YC36" } ], "pmid": "" }, { "name": "protein-containing complex binding", "id": "GO:0044877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044877", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YC36", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YC36" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YC36", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YC36" } ], "pmid": "" } ], "cellular_component": [ { "name": "nuclear pore", "id": "GO:0005643", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005643", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YC36", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YC36" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YC36", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YC36" } ], "pmid": "" }, { "name": "nuclear pore nuclear basket", "id": "GO:0044615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044615", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YC36", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YC36" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YC36", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YC36" } ], "pmid": "" }, { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YC36", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YC36" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YC36", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YC36" } ], "pmid": "" }, { "name": "nuclear pore cytoplasmic filaments", "id": "GO:0044614", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044614", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YC36", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YC36" } ], "pmid": "" }, { "name": "cytoplasmic periphery of the nuclear pore complex", "id": "GO:1990723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990723", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YC36", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YC36" } ], "pmid": "" }, { "name": "nuclear inclusion body", "id": "GO:0042405", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042405", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YC36", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YC36" } ], "pmid": "" }, { "name": "annulate lamellae", "id": "GO:0005642", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005642", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YC36", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YC36" } ], "pmid": "" }, { "name": "SUMO ligase complex", "id": "GO:0106068", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106068", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YC36", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YC36" } ], "pmid": "" } ], "biological_process": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YC36", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YC36" } ], "pmid": "" }, { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YC36", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YC36" } ], "pmid": "" }, { "name": "nuclear export", "id": "GO:0051168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051168", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YC36", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YC36" } ], "pmid": "" }, { "name": "mRNA transport", "id": "GO:0051028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051028", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YC36", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YC36" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YC36", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YC36" } ], "pmid": "" }, { "name": "protein sumoylation", "id": "GO:0016925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016925", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YC36", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YC36" } ], "pmid": "" }, { "name": "response to amphetamine", "id": "GO:0001975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001975", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YC36", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YC36" } ], "pmid": "" }, { "name": "centrosome localization", "id": "GO:0051642", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051642", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YC36", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YC36" } ], "pmid": "" }, { "name": "regulation of gluconeogenesis", "id": "GO:0006111", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006111", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YC36", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YC36" } ], "pmid": "" }, { "name": "NLS-bearing protein import into nucleus", "id": "GO:0006607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006607", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YC36", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YC36" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I5YC36-1", "start_pos": "1020", "end_pos": "1020", "site_lbl": "Thr1020", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1020, "start_aa": "Thr", "end_pos": 1020, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1020", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I5YC36-1" }, { "uniprot_canonical_ac": "A0A8I5Y874-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y874", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y874" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 523, "chemical_mass": 59417.0, "gene_names": "Adck1;Adck1", "protein_name": "AarF domain-containing protein kinase 1", "disease": [], "molecular_function": [ { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y874", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y874" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y874", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y874" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y874", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y874" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y874", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y874" } ], "pmid": "" } ], "biological_process": [ { "name": "lipid homeostasis", "id": "GO:0055088", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055088", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y874", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y874" } ], "pmid": "" }, { "name": "mitochondrion organization", "id": "GO:0007005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007005", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y874", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y874" } ], "pmid": "" }, { "name": "positive regulation of cristae formation", "id": "GO:1903852", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903852", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y874", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y874" } ], "pmid": "" }, { "name": "negative regulation of mitochondrial fusion", "id": "GO:0010637", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010637", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y874", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y874" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5Y874-1" }, { "uniprot_canonical_ac": "A0A8I6G5G3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G5G3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G5G3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 286, "chemical_mass": 31941.0, "gene_names": "Tango2;RGD1310348;Tango2", "protein_name": "", "disease": [ { "disease_id": "DOID:0081386", "name": "TANGO2-related metabolic encephalopathy and arrythmias", "description": "A syndrome that is characterized by episodic metabolic degeneration affecting skeletal muscle, cardiac muscle, and the nervous system and that has_material_basis_in homozygous or compound heterozygous mutation in the TANGO2 gene on chromosome 22q11.", "url": "https://disease-ontology.org/term/DOID:0081386", "evidence": [ { "id": "0081386", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081386" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G5G3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G5G3" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G5G3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G5G3" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G5G3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G5G3" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G5G3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G5G3" } ], "pmid": "" } ], "biological_process": [ { "name": "protein secretion", "id": "GO:0009306", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009306", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G5G3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G5G3" } ], "pmid": "" }, { "name": "Golgi organization", "id": "GO:0007030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007030", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G5G3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G5G3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6G5G3-1" }, { "uniprot_canonical_ac": "A0A8I5ZM01-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZM01", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZM01" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 897, "chemical_mass": 102928.0, "gene_names": "Evi5;Evi5", "protein_name": "", "disease": [], "molecular_function": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZM01", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZM01" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZM01", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZM01" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZM01", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZM01" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of GTPase activity", "id": "GO:0043547", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043547", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZM01", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZM01" } ], "pmid": "" }, { "name": "retrograde transport, endosome to Golgi", "id": "GO:0042147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042147", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZM01", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZM01" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZM01-1" }, { "uniprot_canonical_ac": "A0A8I6GDZ5-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GDZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GDZ5" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 385, "chemical_mass": 43852.0, "gene_names": "Mettl2;Mettl2a;Mettl2b;Mettl2", "protein_name": "tRNA N(3)-cytidine methyltransferase", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GDZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GDZ5" } ], "pmid": "" } ], "biological_process": [ { "name": "tRNA processing", "id": "GO:0008033", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008033", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GDZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GDZ5" } ], "pmid": "" }, { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GDZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GDZ5" } ], "pmid": "" }, { "name": "tRNA metabolic process", "id": "GO:0006399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006399", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GDZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GDZ5" } ], "pmid": "" }, { "name": "tRNA modification", "id": "GO:0006400", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006400", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GDZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GDZ5" } ], "pmid": "" }, { "name": "tRNA methylation", "id": "GO:0030488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030488", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GDZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GDZ5" } ], "pmid": "" } ], "molecular_function": [ { "name": "S-adenosylmethionine-dependent methyltransferase activity", "id": "GO:0008757", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008757", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GDZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GDZ5" } ], "pmid": "" }, { "name": "RNA methyltransferase activity", "id": "GO:0008173", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008173", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GDZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GDZ5" } ], "pmid": "" }, { "name": "tRNA (cytidine-3-)-methyltransferase activity", "id": "GO:0052735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052735", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GDZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GDZ5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6GDZ5-1" }, { "uniprot_canonical_ac": "A0A8I6B288-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B288", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B288" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 525, "chemical_mass": 56613.0, "gene_names": "Nab2;Nab2", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B288", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B288" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B288", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B288" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B288", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B288" } ], "pmid": "" }, { "name": "Schwann cell differentiation", "id": "GO:0014037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014037", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B288", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B288" } ], "pmid": "" }, { "name": "endochondral ossification", "id": "GO:0001958", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001958", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B288", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B288" } ], "pmid": "" }, { "name": "regulation of epidermis development", "id": "GO:0045682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045682", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B288", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B288" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B288", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B288" } ], "pmid": "" }, { "name": "myelination", "id": "GO:0042552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042552", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B288", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B288" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase III", "id": "GO:0016480", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016480", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B288", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B288" } ], "pmid": "" } ], "molecular_function": [ { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B288", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B288" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B288", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B288" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6B288-1", "start_pos": "8", "end_pos": "8", "site_lbl": "Thr8", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 8, "start_aa": "Thr", "end_pos": 8, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr8", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6B288-1" }, { "uniprot_canonical_ac": "A0A8I6AB31-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AB31", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AB31" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 597, "chemical_mass": 68623.0, "gene_names": "Cdc23;Cdc23", "protein_name": "Cell division cycle protein 23 homolog", "disease": [ { "disease_id": "DOID:5223", "name": "infertility", "description": "", "url": "https://disease-ontology.org/term/DOID:5223", "evidence": [ { "id": "5223", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5223" } ], "weight": 0.0 } ], "biological_process": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AB31", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AB31" } ], "pmid": "" }, { "name": "mitotic cell cycle", "id": "GO:0000278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000278", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AB31", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AB31" } ], "pmid": "" }, { "name": "anaphase-promoting complex-dependent catabolic process", "id": "GO:0031145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031145", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AB31", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AB31" } ], "pmid": "" }, { "name": "protein K11-linked ubiquitination", "id": "GO:0070979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070979", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AB31", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AB31" } ], "pmid": "" }, { "name": "mitotic metaphase chromosome alignment", "id": "GO:0007080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007080", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AB31", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AB31" } ], "pmid": "" }, { "name": "regulation of mitotic metaphase/anaphase transition", "id": "GO:0030071", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030071", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AB31", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AB31" } ], "pmid": "" }, { "name": "protein K48-linked ubiquitination", "id": "GO:0070936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070936", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AB31", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AB31" } ], "pmid": "" }, { "name": "protein branched polyubiquitination", "id": "GO:0141198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141198", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AB31", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AB31" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AB31", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AB31" } ], "pmid": "" }, { "name": "positive regulation of mitotic metaphase/anaphase transition", "id": "GO:0045842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045842", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AB31", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AB31" } ], "pmid": "" } ], "cellular_component": [ { "name": "anaphase-promoting complex", "id": "GO:0005680", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005680", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AB31", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AB31" } ], "pmid": "" } ], "molecular_function": [ { "name": "enzyme-substrate adaptor activity", "id": "GO:0140767", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140767", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AB31", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AB31" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AB31-1" }, { "uniprot_canonical_ac": "A0A8I6AGD6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AGD6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AGD6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1027, "chemical_mass": 113566.0, "gene_names": "Elapor2;Elapor2;RGD1563349", "protein_name": "", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AGD6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AGD6" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AGD6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AGD6" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of BMP signaling pathway", "id": "GO:0030513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030513", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AGD6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AGD6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AGD6-1" }, { "uniprot_canonical_ac": "A0A8I6AGJ9-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AGJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AGJ9" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 129, "chemical_mass": 14262.0, "gene_names": "Gemin7;Gemin7", "protein_name": "Gem-associated protein 7", "disease": [], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AGJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AGJ9" } ], "pmid": "" } ], "biological_process": [ { "name": "spliceosomal snRNP assembly", "id": "GO:0000387", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000387", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AGJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AGJ9" } ], "pmid": "" } ], "cellular_component": [ { "name": "SMN-Sm protein complex", "id": "GO:0034719", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034719", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AGJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AGJ9" } ], "pmid": "" }, { "name": "Gemini of Cajal bodies", "id": "GO:0097504", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097504", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AGJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AGJ9" } ], "pmid": "" }, { "name": "Sm-like protein family complex", "id": "GO:0120114", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120114", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AGJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AGJ9" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AGJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AGJ9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AGJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AGJ9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AGJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AGJ9" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AGJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AGJ9" } ], "pmid": "" }, { "name": "SMN complex", "id": "GO:0032797", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032797", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AGJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AGJ9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AGJ9-1" }, { "uniprot_canonical_ac": "A0A8I5ZUH3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUH3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUH3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 613, "chemical_mass": 67405.0, "gene_names": "Plekhn1;Plekhn1;RGD1311019", "protein_name": "Cardiolipin and phosphatidic acid-binding protein", "disease": [], "cellular_component": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUH3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUH3" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUH3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUH3" } ], "pmid": "" }, { "name": "mitochondrial membrane", "id": "GO:0031966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031966", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUH3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUH3" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUH3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUH3" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of apoptotic process", "id": "GO:0043065", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043065", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUH3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUH3" } ], "pmid": "" }, { "name": "response to hypoxia", "id": "GO:0001666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001666", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUH3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUH3" } ], "pmid": "" }, { "name": "3'-UTR-mediated mRNA destabilization", "id": "GO:0061158", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061158", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUH3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUH3" } ], "pmid": "" } ], "molecular_function": [ { "name": "phosphatidylserine binding", "id": "GO:0001786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001786", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUH3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUH3" } ], "pmid": "" }, { "name": "phosphatidylinositol phosphate binding", "id": "GO:1901981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901981", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUH3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUH3" } ], "pmid": "" }, { "name": "phosphatidic acid binding", "id": "GO:0070300", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070300", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUH3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUH3" } ], "pmid": "" }, { "name": "cardiolipin binding", "id": "GO:1901612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901612", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUH3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUH3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZUH3-1" }, { "uniprot_canonical_ac": "A0A8I6AMX2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AMX2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AMX2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 312, "chemical_mass": 35403.0, "gene_names": "Olr906;Or6c206;Olr943", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AMX2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AMX2" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AMX2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AMX2" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AMX2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AMX2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AMX2-1" }, { "uniprot_canonical_ac": "A0A8I6A183-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A183", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A183" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1137, "chemical_mass": 130874.0, "gene_names": "Ccar1", "protein_name": "Cell division cycle and apoptosis regulator protein 1", "disease": [], "molecular_function": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A183", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A183" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A183", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A183" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A183", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A183" } ], "pmid": "" }, { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A183", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A183" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A183", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A183" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A183", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A183" } ], "pmid": "" }, { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A183", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A183" } ], "pmid": "" }, { "name": "positive regulation of cell migration", "id": "GO:0030335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030335", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A183", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A183" } ], "pmid": "" }, { "name": "positive regulation of apoptotic process", "id": "GO:0043065", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043065", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A183", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A183" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A183", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A183" } ], "pmid": "" } ], "cellular_component": [ { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A183", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A183" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A183", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A183" } ], "pmid": "" }, { "name": "nuclear envelope lumen", "id": "GO:0005641", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005641", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A183", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A183" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A183", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A183" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A183", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A183" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6A183-1" }, { "uniprot_canonical_ac": "A0A8I6ABZ7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1392, "chemical_mass": 150233.0, "gene_names": "Dhx9;Dhx9", "protein_name": "ATP-dependent RNA helicase A", "disease": [ { "disease_id": "DOID:0061048", "name": "autosomal dominant intellectual developmental disorder 75", "description": "An autosomal dominant intellectual developmental disorder that has_material_basis_in heterozygous mutation in the DHX9 gene on chromosome 1q25.", "url": "https://disease-ontology.org/term/DOID:0061048", "evidence": [ { "id": "0061048", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061048" } ], "weight": 0.0 }, { "disease_id": "DOID:1826", "name": "epilepsy", "description": "A brain disease that is characterized by the occurrance of at least two unprovoked seizures resulting from a persistent epileptogenic abnormality of the brain that is able to spontaneously generate paroxysmal activity and typically manifested by sudden brief episodes of altered or diminished consciousness, involuntary movements, or convulsions.", "url": "https://disease-ontology.org/term/DOID:1826", "evidence": [ { "id": "1826", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1826" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "double-stranded RNA binding", "id": "GO:0003725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003725", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "RNA helicase activity", "id": "GO:0003724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003724", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "3'-5' DNA/RNA helicase activity", "id": "GO:0033679", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033679", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "DNA replication origin binding", "id": "GO:0003688", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003688", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "3'-5' DNA helicase activity", "id": "GO:0043138", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043138", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "regulatory region RNA binding", "id": "GO:0001069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001069", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "triplex DNA binding", "id": "GO:0045142", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045142", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "importin-alpha family protein binding", "id": "GO:0061676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061676", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "RISC complex binding", "id": "GO:1905172", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905172", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "single-stranded 3'-5' DNA helicase activity", "id": "GO:1990518", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990518", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "sequence-specific mRNA binding", "id": "GO:1990825", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990825", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "double-stranded DNA binding", "id": "GO:0003690", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003690", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "single-stranded RNA binding", "id": "GO:0003727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003727", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "chromatin DNA binding", "id": "GO:0031490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031490", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "ribosome binding", "id": "GO:0043022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043022", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "RNA polymerase II complex binding", "id": "GO:0000993", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000993", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "siRNA binding", "id": "GO:0035197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035197", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "RNA polymerase binding", "id": "GO:0070063", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070063", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "single-stranded DNA binding", "id": "GO:0003697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003697", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "RNA polymerase II-specific DNA-binding transcription factor binding", "id": "GO:0061629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061629", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "nucleoside triphosphate diphosphatase activity", "id": "GO:0047429", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047429", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "DNA helicase activity", "id": "GO:0003678", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003678", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "3'-5' RNA helicase activity", "id": "GO:0034458", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034458", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "promoter-specific chromatin binding", "id": "GO:1990841", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990841", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "RNA stem-loop binding", "id": "GO:0035613", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035613", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "G-quadruplex unwinding activity", "id": "GO:0160225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160225", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "perichromatin fibrils", "id": "GO:0005726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005726", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "nuclear stress granule", "id": "GO:0097165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097165", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "cytoplasmic ribonucleoprotein granule", "id": "GO:0036464", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036464", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "RISC complex", "id": "GO:0016442", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016442", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "RISC-loading complex", "id": "GO:0070578", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070578", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "CRD-mediated mRNA stability complex", "id": "GO:0070937", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070937", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription termination", "id": "GO:0006353", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006353", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "cellular response to exogenous dsRNA", "id": "GO:0071360", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071360", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "positive regulation of interferon-alpha production", "id": "GO:0032727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032727", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "protein localization to cytoplasmic stress granule", "id": "GO:1903608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903608", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "positive regulation of interleukin-18 production", "id": "GO:0032741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032741", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "DNA-templated viral transcription", "id": "GO:0039695", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0039695", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "positive regulation of RNA export from nucleus", "id": "GO:0046833", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046833", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "regulation of defense response to virus by host", "id": "GO:0050691", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050691", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "positive regulation of response to cytokine stimulus", "id": "GO:0060760", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060760", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "RISC complex assembly", "id": "GO:0070922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070922", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "CRD-mediated mRNA stabilization", "id": "GO:0070934", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070934", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "regulation of cytoplasmic translation", "id": "GO:2000765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000765", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "positive regulation of cytoplasmic translation", "id": "GO:2000767", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000767", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "positive regulation of interleukin-6 production", "id": "GO:0032755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032755", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "cellular response to heat", "id": "GO:0034605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034605", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "circadian rhythm", "id": "GO:0007623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007623", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "positive regulation of DNA repair", "id": "GO:0045739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045739", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "positive regulation of inflammatory response", "id": "GO:0050729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050729", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "positive regulation of tumor necrosis factor production", "id": "GO:0032760", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032760", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "positive regulation of fibroblast proliferation", "id": "GO:0048146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048146", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "miRNA-mediated post-transcriptional gene silencing", "id": "GO:0035195", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035195", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "positive regulation of DNA replication", "id": "GO:0045740", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045740", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "pyroptotic inflammatory response", "id": "GO:0070269", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070269", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "positive regulation of innate immune response", "id": "GO:0045089", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045089", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "positive regulation of viral transcription", "id": "GO:0050434", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050434", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "mRNA transport", "id": "GO:0051028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051028", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "positive regulation of interferon-beta production", "id": "GO:0032728", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032728", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "alternative mRNA splicing, via spliceosome", "id": "GO:0000380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000380", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "regulation of mRNA processing", "id": "GO:0050684", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050684", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "protein-containing complex assembly", "id": "GO:0065003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0065003", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" }, { "name": "negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay", "id": "GO:1900152", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900152", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABZ7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6ABZ7-1", "start_pos": "141", "end_pos": "141", "site_lbl": "Thr141", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 141, "start_aa": "Thr", "end_pos": 141, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr141", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6ABZ7-1" }, { "uniprot_canonical_ac": "A0A8I5ZP11-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZP11", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZP11" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 462, "chemical_mass": 49814.0, "gene_names": "Smtnl1", "protein_name": "", "disease": [], "molecular_function": [ { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZP11", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZP11" } ], "pmid": "" }, { "name": "protein phosphatase 1 binding", "id": "GO:0008157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008157", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZP11", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZP11" } ], "pmid": "" }, { "name": "disordered domain specific binding", "id": "GO:0097718", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097718", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZP11", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZP11" } ], "pmid": "" }, { "name": "tropomyosin binding", "id": "GO:0005523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005523", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZP11", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZP11" } ], "pmid": "" }, { "name": "CH domain binding", "id": "GO:0051401", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051401", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZP11", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZP11" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZP11", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZP11" } ], "pmid": "" }, { "name": "I band", "id": "GO:0031674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031674", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZP11", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZP11" } ], "pmid": "" }, { "name": "M band", "id": "GO:0031430", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031430", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZP11", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZP11" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZP11", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZP11" } ], "pmid": "" }, { "name": "contractile muscle fiber", "id": "GO:0043292", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043292", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZP11", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZP11" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZP11", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZP11" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZP11", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZP11" } ], "pmid": "" }, { "name": "positive regulation of vasoconstriction", "id": "GO:0045907", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045907", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZP11", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZP11" } ], "pmid": "" }, { "name": "vasoconstriction", "id": "GO:0042310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042310", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZP11", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZP11" } ], "pmid": "" }, { "name": "response to activity", "id": "GO:0014823", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014823", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZP11", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZP11" } ], "pmid": "" }, { "name": "peptidyl-serine phosphorylation", "id": "GO:0018105", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018105", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZP11", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZP11" } ], "pmid": "" }, { "name": "response to xenobiotic stimulus", "id": "GO:0009410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009410", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZP11", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZP11" } ], "pmid": "" }, { "name": "muscle organ morphogenesis", "id": "GO:0048644", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048644", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZP11", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZP11" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I5ZP11-1", "start_pos": "18", "end_pos": "18", "site_lbl": "Thr18", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 18, "start_aa": "Thr", "end_pos": 18, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr18", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I5ZP11-1", "start_pos": "248", "end_pos": "248", "site_lbl": "Thr248", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 248, "start_aa": "Thr", "end_pos": 248, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr248", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I5ZP11-1", "start_pos": "24", "end_pos": "24", "site_lbl": "Thr24", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 24, "start_aa": "Thr", "end_pos": 24, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr24", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I5ZP11-1", "start_pos": "286", "end_pos": "286", "site_lbl": "Thr286", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 286, "start_aa": "Thr", "end_pos": 286, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr286", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I5ZP11-1" }, { "uniprot_canonical_ac": "A0A8I6A0V9-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A0V9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A0V9" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 698, "chemical_mass": 78156.0, "gene_names": "Mier1;Mier1;RGD1562337", "protein_name": "Mesoderm induction early response protein 1", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A0V9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A0V9" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A0V9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A0V9" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A0V9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A0V9" } ], "pmid": "" }, { "name": "transcription repressor complex", "id": "GO:0017053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017053", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A0V9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A0V9" } ], "pmid": "" }, { "name": "histone deacetylase complex", "id": "GO:0000118", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000118", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A0V9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A0V9" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A0V9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A0V9" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A0V9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A0V9" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A0V9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A0V9" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A0V9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A0V9" } ], "pmid": "" } ], "molecular_function": [ { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A0V9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A0V9" } ], "pmid": "" }, { "name": "histone deacetylase binding", "id": "GO:0042826", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042826", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A0V9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A0V9" } ], "pmid": "" }, { "name": "histone deacetylase activity", "id": "GO:0004407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004407", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A0V9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A0V9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6A0V9-1", "start_pos": "567", "end_pos": "567", "site_lbl": "Thr567", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 567, "start_aa": "Thr", "end_pos": 567, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr567", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I6A0V9-1", "start_pos": "616", "end_pos": "616", "site_lbl": "Thr616", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 616, "start_aa": "Thr", "end_pos": 616, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr616", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I6A0V9-1", "start_pos": "660", "end_pos": "660", "site_lbl": "Arg660", "weight": 0.0, "snv": [ { "sequence_org": "R", "sequence_mut": "S", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (NER->NES).", "chr_id": "5", "chr_pos": "123153616", "evidence": [ { "id": "rs3320666864", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3320666864" } ] } ] } ], "record_id": "A0A8I6A0V9-1" }, { "uniprot_canonical_ac": "A0A8I5Y7F3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y7F3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y7F3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1000, "chemical_mass": 111304.0, "gene_names": "Amotl1", "protein_name": "", "disease": [], "cellular_component": [ { "name": "anchoring junction", "id": "GO:0070161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070161", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y7F3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y7F3" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y7F3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y7F3" } ], "pmid": "" }, { "name": "bicellular tight junction", "id": "GO:0005923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005923", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y7F3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y7F3" } ], "pmid": "" }, { "name": "lamellipodium", "id": "GO:0030027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030027", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y7F3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y7F3" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y7F3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y7F3" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y7F3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y7F3" } ], "pmid": "" }, { "name": "COP9 signalosome", "id": "GO:0008180", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008180", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y7F3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y7F3" } ], "pmid": "" } ], "biological_process": [ { "name": "angiogenesis", "id": "GO:0001525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001525", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y7F3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y7F3" } ], "pmid": "" }, { "name": "hippo signaling", "id": "GO:0035329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035329", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y7F3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y7F3" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y7F3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y7F3" } ], "pmid": "" }, { "name": "regulation of cell migration", "id": "GO:0030334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030334", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y7F3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y7F3" } ], "pmid": "" }, { "name": "establishment of cell polarity involved in ameboidal cell migration", "id": "GO:0003365", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003365", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y7F3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y7F3" } ], "pmid": "" }, { "name": "positive regulation of blood vessel endothelial cell migration", "id": "GO:0043536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043536", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y7F3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y7F3" } ], "pmid": "" } ], "molecular_function": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y7F3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y7F3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5Y7F3-1" }, { "uniprot_canonical_ac": "A0A8I5ZRT6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZRT6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZRT6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1829, "chemical_mass": 211717.0, "gene_names": "Dock2;AABR07029272.1;Dock2", "protein_name": "", "disease": [ { "disease_id": "DOID:0111951", "name": "immunodeficiency 40", "description": "A combined T cell and B cell immunodeficiency characterized by reduced T-cell number and function, with variable defects in B-cell and NK-cell function resulting in onset in early childhood of invasive bacterial and viral infections that has_material_basis_in homozygous or compound heterozygous mutation in the DOCK2 gene on chromosome 5q35.1.", "url": "https://disease-ontology.org/term/DOID:0111951", "evidence": [ { "id": "0111951", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111951" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZRT6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZRT6" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZRT6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZRT6" } ], "pmid": "" } ], "molecular_function": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZRT6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZRT6" } ], "pmid": "" }, { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZRT6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZRT6" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZRT6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZRT6" } ], "pmid": "" }, { "name": "T cell receptor binding", "id": "GO:0042608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042608", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZRT6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZRT6" } ], "pmid": "" } ], "biological_process": [ { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZRT6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZRT6" } ], "pmid": "" }, { "name": "alpha-beta T cell proliferation", "id": "GO:0046633", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046633", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZRT6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZRT6" } ], "pmid": "" }, { "name": "alpha-beta T cell activation", "id": "GO:0046631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046631", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZRT6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZRT6" } ], "pmid": "" }, { "name": "chemotaxis", "id": "GO:0006935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006935", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZRT6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZRT6" } ], "pmid": "" }, { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZRT6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZRT6" } ], "pmid": "" }, { "name": "T cell activation", "id": "GO:0042110", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042110", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZRT6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZRT6" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZRT6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZRT6" } ], "pmid": "" }, { "name": "cytoskeleton organization", "id": "GO:0007010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007010", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZRT6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZRT6" } ], "pmid": "" }, { "name": "positive regulation of phagocytosis", "id": "GO:0050766", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050766", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZRT6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZRT6" } ], "pmid": "" }, { "name": "myoblast fusion", "id": "GO:0007520", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007520", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZRT6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZRT6" } ], "pmid": "" }, { "name": "negative thymic T cell selection", "id": "GO:0045060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045060", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZRT6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZRT6" } ], "pmid": "" }, { "name": "myeloid dendritic cell activation involved in immune response", "id": "GO:0002277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002277", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZRT6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZRT6" } ], "pmid": "" }, { "name": "macropinocytosis", "id": "GO:0044351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044351", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZRT6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZRT6" } ], "pmid": "" }, { "name": "positive thymic T cell selection", "id": "GO:0045059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045059", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZRT6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZRT6" } ], "pmid": "" }, { "name": "immunological synapse formation", "id": "GO:0001771", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001771", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZRT6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZRT6" } ], "pmid": "" }, { "name": "establishment of T cell polarity", "id": "GO:0001768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001768", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZRT6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZRT6" } ], "pmid": "" }, { "name": "membrane raft polarization", "id": "GO:0001766", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001766", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZRT6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZRT6" } ], "pmid": "" }, { "name": "T cell proliferation", "id": "GO:0042098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042098", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZRT6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZRT6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I5ZRT6-1", "start_pos": "1657", "end_pos": "1657", "site_lbl": "Thr1657", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1657, "start_aa": "Thr", "end_pos": 1657, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1657", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I5ZRT6-1" }, { "uniprot_canonical_ac": "A0A8I5ZW96-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZW96", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZW96" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 122, "chemical_mass": 13466.0, "gene_names": "Ormdl1;Ormdl1", "protein_name": "", "disease": [], "biological_process": [ { "name": "negative regulation of ceramide biosynthetic process", "id": "GO:1900060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900060", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZW96", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZW96" } ], "pmid": "" }, { "name": "ceramide metabolic process", "id": "GO:0006672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006672", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZW96", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZW96" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZW96", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZW96" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZW96", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZW96" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZW96-1" }, { "uniprot_canonical_ac": "A0A8I6AG17-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AG17", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AG17" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 291, "chemical_mass": 31182.0, "gene_names": "Tmem219;RGD1560566;Tmem219", "protein_name": "", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AG17", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AG17" } ], "pmid": "" }, { "name": "receptor complex", "id": "GO:0043235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043235", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AG17", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AG17" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AG17-1" }, { "uniprot_canonical_ac": "A0A8I6AGS9-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AGS9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AGS9" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 312, "chemical_mass": 35164.0, "gene_names": "Or5aq7b;Olr552;Or5aq7b", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AGS9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AGS9" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AGS9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AGS9" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AGS9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AGS9" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AGS9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AGS9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AGS9-1" }, { "uniprot_canonical_ac": "A0A8I6AIF3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AIF3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AIF3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 315, "chemical_mass": 35663.0, "gene_names": "Or4k52", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AIF3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AIF3" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AIF3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AIF3" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AIF3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AIF3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AIF3-1" }, { "uniprot_canonical_ac": "A0A8I6AJM1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJM1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJM1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 312, "chemical_mass": 35032.0, "gene_names": "Or4f61d;Olr790;Or4f61d", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJM1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJM1" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJM1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJM1" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJM1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJM1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AJM1-1" }, { "uniprot_canonical_ac": "A0A8I6AKE5-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AKE5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AKE5" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 350, "chemical_mass": 39596.0, "gene_names": "Or8g28;Olr1283;Or8g20e;tpcr21", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AKE5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AKE5" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AKE5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AKE5" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AKE5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AKE5" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AKE5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AKE5" } ], "pmid": "" } ], "biological_process": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AKE5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AKE5" } ], "pmid": "" }, { "name": "sensory perception of smell", "id": "GO:0007608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007608", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AKE5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AKE5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AKE5-1" }, { "uniprot_canonical_ac": "A0A8I6AKY5-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AKY5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AKY5" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 157, "chemical_mass": 17787.0, "gene_names": "Actg1-ps9", "protein_name": "", "disease": [], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AKY5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AKY5" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AKY5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AKY5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AKY5-1" }, { "uniprot_canonical_ac": "A0A8I6AMD8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AMD8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AMD8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 318, "chemical_mass": 35656.0, "gene_names": "Or51h5;LOC684365;Or51h5", "protein_name": "", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AMD8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AMD8" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AMD8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AMD8" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AMD8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AMD8" } ], "pmid": "" } ], "biological_process": [ { "name": "cellular response to lipid", "id": "GO:0071396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071396", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AMD8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AMD8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AMD8-1" }, { "uniprot_canonical_ac": "A0A8I6AMN5-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AMN5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AMN5" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 327, "chemical_mass": 37019.0, "gene_names": "Or6d13b;Olr825;Or6d13b;SCR G-14;SCR G-15", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AMN5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AMN5" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AMN5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AMN5" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AMN5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AMN5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AMN5-1" }, { "uniprot_canonical_ac": "A0A8I6ANT0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ANT0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ANT0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 310, "chemical_mass": 35049.0, "gene_names": "Or10j27;Olr1579;Or10j27", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ANT0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ANT0" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ANT0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ANT0" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ANT0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ANT0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6ANT0-1" }, { "uniprot_canonical_ac": "A0A8I6AS28-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AS28", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AS28" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 308, "chemical_mass": 34903.0, "gene_names": "Or5k3;Olr1542;Or5k3", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AS28", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AS28" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AS28", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AS28" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AS28", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AS28" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AS28-1" }, { "uniprot_canonical_ac": "A0A8I6ASN7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ASN7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ASN7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 292, "chemical_mass": 33949.0, "gene_names": "Stx19;Stx19", "protein_name": "Syntaxin-19", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ASN7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ASN7" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ASN7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ASN7" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ASN7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ASN7" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ASN7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ASN7" } ], "pmid": "" } ], "molecular_function": [ { "name": "SNAP receptor activity", "id": "GO:0005484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005484", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ASN7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ASN7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6ASN7-1" }, { "uniprot_canonical_ac": "A0A8I6AT07-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AT07", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AT07" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 690, "chemical_mass": 77521.0, "gene_names": "Kbtbd7;Kbtbd7", "protein_name": "", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AT07", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AT07" } ], "pmid": "" }, { "name": "Cul3-RING ubiquitin ligase complex", "id": "GO:0031463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031463", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AT07", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AT07" } ], "pmid": "" } ], "biological_process": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AT07", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AT07" } ], "pmid": "" }, { "name": "protein K48-linked ubiquitination", "id": "GO:0070936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070936", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AT07", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AT07" } ], "pmid": "" }, { "name": "regulation of Rac protein signal transduction", "id": "GO:0035020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035020", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AT07", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AT07" } ], "pmid": "" } ], "molecular_function": [ { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AT07", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AT07" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AT07-1" }, { "uniprot_canonical_ac": "A0A8I6AUW5-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AUW5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AUW5" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 46, "chemical_mass": 5230.0, "gene_names": "Mrln;Mln;Mrln", "protein_name": "", "disease": [], "biological_process": [ { "name": "negative regulation of ATPase-coupled calcium transmembrane transporter activity", "id": "GO:1901895", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901895", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AUW5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AUW5" } ], "pmid": "" }, { "name": "response to wounding", "id": "GO:0009611", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009611", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AUW5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AUW5" } ], "pmid": "" }, { "name": "negative regulation of calcium ion import into sarcoplasmic reticulum", "id": "GO:1902081", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902081", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AUW5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AUW5" } ], "pmid": "" } ], "molecular_function": [ { "name": "enzyme inhibitor activity", "id": "GO:0004857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004857", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AUW5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AUW5" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AUW5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AUW5" } ], "pmid": "" }, { "name": "sarcoplasmic reticulum membrane", "id": "GO:0033017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033017", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AUW5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AUW5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AUW5-1" }, { "uniprot_canonical_ac": "A0A8I6AWU5-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AWU5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AWU5" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 331, "chemical_mass": 37109.0, "gene_names": "Mageb3;Mageb3;RGD1562343", "protein_name": "", "disease": [], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AWU5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AWU5" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AWU5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AWU5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AWU5-1" }, { "uniprot_canonical_ac": "A0A8I6B5F8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B5F8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B5F8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 309, "chemical_mass": 35294.0, "gene_names": "Or5h17c;Olr1557;Or5h17c", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B5F8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B5F8" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B5F8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B5F8" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B5F8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B5F8" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B5F8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B5F8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6B5F8-1" }, { "uniprot_canonical_ac": "A0A8I6G1L1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G1L1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G1L1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 203, "chemical_mass": 22650.0, "gene_names": "RGD1559747;RGD1559747", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G1L1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G1L1" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G1L1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G1L1" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G1L1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G1L1" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G1L1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G1L1" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G1L1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G1L1" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G1L1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G1L1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6G1L1-1" }, { "uniprot_canonical_ac": "A0A8I6G3S1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3S1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3S1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 583, "chemical_mass": 63101.0, "gene_names": "Mon1b;Mon1b;RGD1309977", "protein_name": "Vacuolar fusion protein MON1 homolog", "disease": [], "biological_process": [ { "name": "early viral transcription", "id": "GO:0019085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019085", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3S1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3S1" } ], "pmid": "" }, { "name": "late viral transcription", "id": "GO:0019086", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019086", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3S1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3S1" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3S1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3S1" } ], "pmid": "" }, { "name": "protein targeting to vacuole", "id": "GO:0006623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006623", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3S1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3S1" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3S1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3S1" } ], "pmid": "" }, { "name": "late endosome", "id": "GO:0005770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005770", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3S1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3S1" } ], "pmid": "" }, { "name": "Mon1-Ccz1 complex", "id": "GO:0035658", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035658", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3S1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3S1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6G3S1-1" }, { "uniprot_canonical_ac": "A0A8I6G966-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G966", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G966" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 310, "chemical_mass": 34333.0, "gene_names": "Or13a27d;Olr310;Or13a27d", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G966", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G966" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G966", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G966" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G966", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G966" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G966", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G966" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6G966-1" }, { "uniprot_canonical_ac": "A0A8I6G9V2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G9V2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G9V2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 302, "chemical_mass": 34946.0, "gene_names": "Vom1r87;V1rc17;Vom1r87", "protein_name": "Vomeronasal type-1 receptor", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G9V2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G9V2" } ], "pmid": "" } ], "biological_process": [ { "name": "response to pheromone", "id": "GO:0019236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019236", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G9V2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G9V2" } ], "pmid": "" }, { "name": "sensory perception of chemical stimulus", "id": "GO:0007606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007606", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G9V2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G9V2" } ], "pmid": "" } ], "molecular_function": [ { "name": "pheromone binding", "id": "GO:0005550", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005550", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G9V2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G9V2" } ], "pmid": "" }, { "name": "pheromone receptor activity", "id": "GO:0016503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016503", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G9V2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G9V2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6G9V2-1" }, { "uniprot_canonical_ac": "A0A8I6GI15-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI15", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI15" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 501, "chemical_mass": 56566.0, "gene_names": "Smok2al1;RGD1560718;Smok2al1", "protein_name": "non-specific serine/threonine protein kinase", "disease": [], "molecular_function": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI15", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI15" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI15", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI15" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6GI15-1", "start_pos": "414", "end_pos": "414", "site_lbl": "Thr414", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 414, "start_aa": "Thr", "end_pos": 414, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr414", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6GI15-1" }, { "uniprot_canonical_ac": "A0A8I6GIN6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GIN6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GIN6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 262, "chemical_mass": 27976.0, "gene_names": "Prr23a2;Prr23a2;Prr23d2", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6GIN6-1" }, { "uniprot_canonical_ac": "A0A8I6GK27-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GK27", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GK27" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 350, "chemical_mass": 40405.0, "gene_names": "RT1-M1-4", "protein_name": "", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GK27", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GK27" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6GK27-1" }, { "uniprot_canonical_ac": "A1A5S0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A1A5S0", "url": "https://www.uniprot.org/uniprotkb/A1A5S0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 189, "chemical_mass": 21575.0, "gene_names": "Gtsf1", "protein_name": "", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A1A5S0", "url": "https://www.uniprot.org/uniprotkb/A1A5S0" } ], "pmid": "" }, { "name": "piP-body", "id": "GO:0071547", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071547", "evidence": [ { "database": "UniProtKB", "id": "A1A5S0", "url": "https://www.uniprot.org/uniprotkb/A1A5S0" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A1A5S0", "url": "https://www.uniprot.org/uniprotkb/A1A5S0" } ], "pmid": "" }, { "name": "tRNA binding", "id": "GO:0000049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000049", "evidence": [ { "database": "UniProtKB", "id": "A1A5S0", "url": "https://www.uniprot.org/uniprotkb/A1A5S0" } ], "pmid": "" } ], "biological_process": [ { "name": "secondary piRNA processing", "id": "GO:0140965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140965", "evidence": [ { "database": "UniProtKB", "id": "A1A5S0", "url": "https://www.uniprot.org/uniprotkb/A1A5S0" } ], "pmid": "" }, { "name": "piRNA-mediated gene silencing by mRNA destabilization", "id": "GO:0140991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140991", "evidence": [ { "database": "UniProtKB", "id": "A1A5S0", "url": "https://www.uniprot.org/uniprotkb/A1A5S0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A1A5S0-1" }, { "uniprot_canonical_ac": "A6Y7S3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A6Y7S3", "url": "https://www.uniprot.org/uniprotkb/A6Y7S3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 476, "chemical_mass": 52822.0, "gene_names": "Kctd8;Kctd8", "protein_name": "", "disease": [], "cellular_component": [ { "name": "receptor complex", "id": "GO:0043235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043235", "evidence": [ { "database": "UniProtKB", "id": "A6Y7S3", "url": "https://www.uniprot.org/uniprotkb/A6Y7S3" } ], "pmid": "" }, { "name": "postsynaptic membrane", "id": "GO:0045211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045211", "evidence": [ { "database": "UniProtKB", "id": "A6Y7S3", "url": "https://www.uniprot.org/uniprotkb/A6Y7S3" } ], "pmid": "" }, { "name": "presynaptic membrane", "id": "GO:0042734", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042734", "evidence": [ { "database": "UniProtKB", "id": "A6Y7S3", "url": "https://www.uniprot.org/uniprotkb/A6Y7S3" } ], "pmid": "" }, { "name": "presynaptic active zone membrane", "id": "GO:0048787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048787", "evidence": [ { "database": "UniProtKB", "id": "A6Y7S3", "url": "https://www.uniprot.org/uniprotkb/A6Y7S3" } ], "pmid": "" }, { "name": "postsynapse", "id": "GO:0098794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098794", "evidence": [ { "database": "UniProtKB", "id": "A6Y7S3", "url": "https://www.uniprot.org/uniprotkb/A6Y7S3" } ], "pmid": "" } ], "biological_process": [ { "name": "protein homooligomerization", "id": "GO:0051260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051260", "evidence": [ { "database": "UniProtKB", "id": "A6Y7S3", "url": "https://www.uniprot.org/uniprotkb/A6Y7S3" } ], "pmid": "" }, { "name": "regulation of G protein-coupled receptor signaling pathway", "id": "GO:0008277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008277", "evidence": [ { "database": "UniProtKB", "id": "A6Y7S3", "url": "https://www.uniprot.org/uniprotkb/A6Y7S3" } ], "pmid": "" } ], "molecular_function": [ { "name": "G protein-coupled neurotransmitter receptor activity involved in regulation of presynaptic membrane potential", "id": "GO:0150047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0150047", "evidence": [ { "database": "UniProtKB", "id": "A6Y7S3", "url": "https://www.uniprot.org/uniprotkb/A6Y7S3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A6Y7S3-1" }, { "uniprot_canonical_ac": "B0BNE7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "B0BNE7", "url": "https://www.uniprot.org/uniprotkb/B0BNE7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 249, "chemical_mass": 27544.0, "gene_names": "Tspan7;A15;DXS1692E;MXS1;TALLA-1;Tm4sf2;Tspan7", "protein_name": "Tetraspanin", "disease": [ { "disease_id": "DOID:0112024", "name": "non-syndromic X-linked intellectual disability 58", "description": "A non-syndromic X-linked intellectual disability characterized by mild to moderate intellectual disability and no consistent dysmorphic features that has_material_basis_in hemizygous mutation in the TSPAN7 gene on chromosome Xp11.4.", "url": "https://disease-ontology.org/term/DOID:0112024", "evidence": [ { "id": "0112024", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112024" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "B0BNE7", "url": "https://www.uniprot.org/uniprotkb/B0BNE7" } ], "pmid": "" }, { "name": "postsynapse", "id": "GO:0098794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098794", "evidence": [ { "database": "UniProtKB", "id": "B0BNE7", "url": "https://www.uniprot.org/uniprotkb/B0BNE7" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of postsynaptic neurotransmitter receptor internalization", "id": "GO:0099149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099149", "evidence": [ { "database": "UniProtKB", "id": "B0BNE7", "url": "https://www.uniprot.org/uniprotkb/B0BNE7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "B0BNE7-1" }, { "uniprot_canonical_ac": "F7EM85-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F7EM85", "url": "https://www.uniprot.org/uniprotkb/F7EM85" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 399, "chemical_mass": 44009.0, "gene_names": "Fbxo22;Fbxo22", "protein_name": "", "disease": [], "biological_process": [ { "name": "regulation of myotube differentiation", "id": "GO:0010830", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010830", "evidence": [ { "database": "UniProtKB", "id": "F7EM85", "url": "https://www.uniprot.org/uniprotkb/F7EM85" } ], "pmid": "" }, { "name": "regulation of skeletal muscle fiber development", "id": "GO:0048742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048742", "evidence": [ { "database": "UniProtKB", "id": "F7EM85", "url": "https://www.uniprot.org/uniprotkb/F7EM85" } ], "pmid": "" }, { "name": "nucleocytoplasmic transport", "id": "GO:0006913", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006913", "evidence": [ { "database": "UniProtKB", "id": "F7EM85", "url": "https://www.uniprot.org/uniprotkb/F7EM85" } ], "pmid": "" }, { "name": "protein polyubiquitination", "id": "GO:0000209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000209", "evidence": [ { "database": "UniProtKB", "id": "F7EM85", "url": "https://www.uniprot.org/uniprotkb/F7EM85" } ], "pmid": "" }, { "name": "cellular response to starvation", "id": "GO:0009267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009267", "evidence": [ { "database": "UniProtKB", "id": "F7EM85", "url": "https://www.uniprot.org/uniprotkb/F7EM85" } ], "pmid": "" }, { "name": "positive regulation of proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0032436", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032436", "evidence": [ { "database": "UniProtKB", "id": "F7EM85", "url": "https://www.uniprot.org/uniprotkb/F7EM85" } ], "pmid": "" }, { "name": "positive regulation of ubiquitin-dependent protein catabolic process", "id": "GO:2000060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000060", "evidence": [ { "database": "UniProtKB", "id": "F7EM85", "url": "https://www.uniprot.org/uniprotkb/F7EM85" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F7EM85", "url": "https://www.uniprot.org/uniprotkb/F7EM85" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F7EM85", "url": "https://www.uniprot.org/uniprotkb/F7EM85" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F7EM85-1" }, { "uniprot_canonical_ac": "F7FJV3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F7FJV3", "url": "https://www.uniprot.org/uniprotkb/F7FJV3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 387, "chemical_mass": 42930.0, "gene_names": "Creb3;Creb3", "protein_name": "", "disease": [], "biological_process": [ { "name": "positive regulation of deacetylase activity", "id": "GO:0090045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090045", "evidence": [ { "database": "UniProtKB", "id": "F7FJV3", "url": "https://www.uniprot.org/uniprotkb/F7FJV3" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F7FJV3", "url": "https://www.uniprot.org/uniprotkb/F7FJV3" } ], "pmid": "" }, { "name": "positive regulation of cell migration", "id": "GO:0030335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030335", "evidence": [ { "database": "UniProtKB", "id": "F7FJV3", "url": "https://www.uniprot.org/uniprotkb/F7FJV3" } ], "pmid": "" }, { "name": "regulation of cell population proliferation", "id": "GO:0042127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042127", "evidence": [ { "database": "UniProtKB", "id": "F7FJV3", "url": "https://www.uniprot.org/uniprotkb/F7FJV3" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "F7FJV3", "url": "https://www.uniprot.org/uniprotkb/F7FJV3" } ], "pmid": "" }, { "name": "positive regulation of monocyte chemotaxis", "id": "GO:0090026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090026", "evidence": [ { "database": "UniProtKB", "id": "F7FJV3", "url": "https://www.uniprot.org/uniprotkb/F7FJV3" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "F7FJV3", "url": "https://www.uniprot.org/uniprotkb/F7FJV3" } ], "pmid": "" }, { "name": "regulation of cell growth", "id": "GO:0001558", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001558", "evidence": [ { "database": "UniProtKB", "id": "F7FJV3", "url": "https://www.uniprot.org/uniprotkb/F7FJV3" } ], "pmid": "" }, { "name": "regulation of apoptotic process", "id": "GO:0042981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042981", "evidence": [ { "database": "UniProtKB", "id": "F7FJV3", "url": "https://www.uniprot.org/uniprotkb/F7FJV3" } ], "pmid": "" }, { "name": "endoplasmic reticulum unfolded protein response", "id": "GO:0030968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030968", "evidence": [ { "database": "UniProtKB", "id": "F7FJV3", "url": "https://www.uniprot.org/uniprotkb/F7FJV3" } ], "pmid": "" }, { "name": "positive regulation of calcium ion transport", "id": "GO:0051928", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051928", "evidence": [ { "database": "UniProtKB", "id": "F7FJV3", "url": "https://www.uniprot.org/uniprotkb/F7FJV3" } ], "pmid": "" }, { "name": "induction of positive chemotaxis", "id": "GO:0050930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050930", "evidence": [ { "database": "UniProtKB", "id": "F7FJV3", "url": "https://www.uniprot.org/uniprotkb/F7FJV3" } ], "pmid": "" }, { "name": "negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway", "id": "GO:1902236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902236", "evidence": [ { "database": "UniProtKB", "id": "F7FJV3", "url": "https://www.uniprot.org/uniprotkb/F7FJV3" } ], "pmid": "" } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "F7FJV3", "url": "https://www.uniprot.org/uniprotkb/F7FJV3" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F7FJV3", "url": "https://www.uniprot.org/uniprotkb/F7FJV3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F7FJV3", "url": "https://www.uniprot.org/uniprotkb/F7FJV3" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "F7FJV3", "url": "https://www.uniprot.org/uniprotkb/F7FJV3" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "F7FJV3", "url": "https://www.uniprot.org/uniprotkb/F7FJV3" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F7FJV3", "url": "https://www.uniprot.org/uniprotkb/F7FJV3" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F7FJV3", "url": "https://www.uniprot.org/uniprotkb/F7FJV3" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "F7FJV3", "url": "https://www.uniprot.org/uniprotkb/F7FJV3" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "F7FJV3", "url": "https://www.uniprot.org/uniprotkb/F7FJV3" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "F7FJV3", "url": "https://www.uniprot.org/uniprotkb/F7FJV3" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulator complex", "id": "GO:0090575", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090575", "evidence": [ { "database": "UniProtKB", "id": "F7FJV3", "url": "https://www.uniprot.org/uniprotkb/F7FJV3" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "F7FJV3", "url": "https://www.uniprot.org/uniprotkb/F7FJV3" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "F7FJV3", "url": "https://www.uniprot.org/uniprotkb/F7FJV3" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "F7FJV3", "url": "https://www.uniprot.org/uniprotkb/F7FJV3" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "F7FJV3", "url": "https://www.uniprot.org/uniprotkb/F7FJV3" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "F7FJV3", "url": "https://www.uniprot.org/uniprotkb/F7FJV3" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "F7FJV3", "url": "https://www.uniprot.org/uniprotkb/F7FJV3" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "F7FJV3", "url": "https://www.uniprot.org/uniprotkb/F7FJV3" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "F7FJV3", "url": "https://www.uniprot.org/uniprotkb/F7FJV3" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "F7FJV3", "url": "https://www.uniprot.org/uniprotkb/F7FJV3" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "F7FJV3", "url": "https://www.uniprot.org/uniprotkb/F7FJV3" } ], "pmid": "" }, { "name": "cAMP response element binding protein binding", "id": "GO:0008140", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008140", "evidence": [ { "database": "UniProtKB", "id": "F7FJV3", "url": "https://www.uniprot.org/uniprotkb/F7FJV3" } ], "pmid": "" }, { "name": "CCR1 chemokine receptor binding", "id": "GO:0031726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031726", "evidence": [ { "database": "UniProtKB", "id": "F7FJV3", "url": "https://www.uniprot.org/uniprotkb/F7FJV3" } ], "pmid": "" }, { "name": "transcription coregulator binding", "id": "GO:0001221", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001221", "evidence": [ { "database": "UniProtKB", "id": "F7FJV3", "url": "https://www.uniprot.org/uniprotkb/F7FJV3" } ], "pmid": "" }, { "name": "sequence-specific double-stranded DNA binding", "id": "GO:1990837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990837", "evidence": [ { "database": "UniProtKB", "id": "F7FJV3", "url": "https://www.uniprot.org/uniprotkb/F7FJV3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F7FJV3-1" }, { "uniprot_canonical_ac": "Q4TU74-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "Q4TU74", "url": "https://www.uniprot.org/uniprotkb/Q4TU74" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 227, "chemical_mass": 25455.0, "gene_names": "Rhoxf9;Psx4;Rhox9;Rhoxf9", "protein_name": "", "disease": [], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q4TU74", "url": "https://www.uniprot.org/uniprotkb/Q4TU74" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "Q4TU74", "url": "https://www.uniprot.org/uniprotkb/Q4TU74" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q4TU74", "url": "https://www.uniprot.org/uniprotkb/Q4TU74" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q4TU74", "url": "https://www.uniprot.org/uniprotkb/Q4TU74" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q4TU74-1" }, { "uniprot_canonical_ac": "Q5FVP4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "Q5FVP4", "url": "https://www.uniprot.org/uniprotkb/Q5FVP4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 580, "chemical_mass": 66698.0, "gene_names": "Zfp35;Zfp239;Zfp35", "protein_name": "Zinc finger protein 271", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q5FVP4", "url": "https://www.uniprot.org/uniprotkb/Q5FVP4" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q5FVP4", "url": "https://www.uniprot.org/uniprotkb/Q5FVP4" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q5FVP4", "url": "https://www.uniprot.org/uniprotkb/Q5FVP4" } ], "pmid": "" }, { "name": "negative regulation of cell differentiation", "id": "GO:0045596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045596", "evidence": [ { "database": "UniProtKB", "id": "Q5FVP4", "url": "https://www.uniprot.org/uniprotkb/Q5FVP4" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q5FVP4", "url": "https://www.uniprot.org/uniprotkb/Q5FVP4" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "Q5FVP4", "url": "https://www.uniprot.org/uniprotkb/Q5FVP4" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "Q5FVP4", "url": "https://www.uniprot.org/uniprotkb/Q5FVP4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q5FVP4-1" }, { "uniprot_canonical_ac": "Q5M857-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "Q5M857", "url": "https://www.uniprot.org/uniprotkb/Q5M857" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 399, "chemical_mass": 45253.0, "gene_names": "Ccnb2", "protein_name": "", "disease": [], "biological_process": [ { "name": "in utero embryonic development", "id": "GO:0001701", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001701", "evidence": [ { "database": "UniProtKB", "id": "Q5M857", "url": "https://www.uniprot.org/uniprotkb/Q5M857" } ], "pmid": "" }, { "name": "regulation of growth", "id": "GO:0040008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040008", "evidence": [ { "database": "UniProtKB", "id": "Q5M857", "url": "https://www.uniprot.org/uniprotkb/Q5M857" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "Q5M857", "url": "https://www.uniprot.org/uniprotkb/Q5M857" } ], "pmid": "" }, { "name": "thymus development", "id": "GO:0048538", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048538", "evidence": [ { "database": "UniProtKB", "id": "Q5M857", "url": "https://www.uniprot.org/uniprotkb/Q5M857" } ], "pmid": "" }, { "name": "G1/S transition of mitotic cell cycle", "id": "GO:0000082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000082", "evidence": [ { "database": "UniProtKB", "id": "Q5M857", "url": "https://www.uniprot.org/uniprotkb/Q5M857" } ], "pmid": "" }, { "name": "T cell homeostasis", "id": "GO:0043029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043029", "evidence": [ { "database": "UniProtKB", "id": "Q5M857", "url": "https://www.uniprot.org/uniprotkb/Q5M857" } ], "pmid": "" }, { "name": "spindle assembly involved in female meiosis I", "id": "GO:0007057", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007057", "evidence": [ { "database": "UniProtKB", "id": "Q5M857", "url": "https://www.uniprot.org/uniprotkb/Q5M857" } ], "pmid": "" }, { "name": "negative regulation of meiotic cell cycle process involved in oocyte maturation", "id": "GO:1904145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904145", "evidence": [ { "database": "UniProtKB", "id": "Q5M857", "url": "https://www.uniprot.org/uniprotkb/Q5M857" } ], "pmid": "" }, { "name": "G2/MI transition of meiotic cell cycle", "id": "GO:0008315", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008315", "evidence": [ { "database": "UniProtKB", "id": "Q5M857", "url": "https://www.uniprot.org/uniprotkb/Q5M857" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q5M857", "url": "https://www.uniprot.org/uniprotkb/Q5M857" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5M857", "url": "https://www.uniprot.org/uniprotkb/Q5M857" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "Q5M857", "url": "https://www.uniprot.org/uniprotkb/Q5M857" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "Q5M857", "url": "https://www.uniprot.org/uniprotkb/Q5M857" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q5M857", "url": "https://www.uniprot.org/uniprotkb/Q5M857" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q5M857", "url": "https://www.uniprot.org/uniprotkb/Q5M857" } ], "pmid": "" }, { "name": "microtubule cytoskeleton", "id": "GO:0015630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015630", "evidence": [ { "database": "UniProtKB", "id": "Q5M857", "url": "https://www.uniprot.org/uniprotkb/Q5M857" } ], "pmid": "" }, { "name": "microtubule organizing center", "id": "GO:0005815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005815", "evidence": [ { "database": "UniProtKB", "id": "Q5M857", "url": "https://www.uniprot.org/uniprotkb/Q5M857" } ], "pmid": "" }, { "name": "cyclin-dependent protein kinase holoenzyme complex", "id": "GO:0000307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000307", "evidence": [ { "database": "UniProtKB", "id": "Q5M857", "url": "https://www.uniprot.org/uniprotkb/Q5M857" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "Q5M857", "url": "https://www.uniprot.org/uniprotkb/Q5M857" } ], "pmid": "" }, { "name": "cyclin-dependent protein serine/threonine kinase regulator activity", "id": "GO:0016538", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016538", "evidence": [ { "database": "UniProtKB", "id": "Q5M857", "url": "https://www.uniprot.org/uniprotkb/Q5M857" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q5M857-1" }, { "uniprot_canonical_ac": "Q5UCE3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "Q5UCE3", "url": "https://www.uniprot.org/uniprotkb/Q5UCE3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 366, "chemical_mass": 40918.0, "gene_names": "Lefty2;Ebaf2;Lefty2", "protein_name": "Left-right determination factor", "disease": [ { "disease_id": "DOID:1682", "name": "congenital heart disease", "description": "A physical disorder that is characterized by problems with the heart's structure that are present at birth.", "url": "https://disease-ontology.org/term/DOID:1682", "evidence": [ { "id": "1682", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1682" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q5UCE3", "url": "https://www.uniprot.org/uniprotkb/Q5UCE3" } ], "pmid": "" } ], "molecular_function": [ { "name": "cytokine activity", "id": "GO:0005125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005125", "evidence": [ { "database": "UniProtKB", "id": "Q5UCE3", "url": "https://www.uniprot.org/uniprotkb/Q5UCE3" } ], "pmid": "" }, { "name": "transforming growth factor beta receptor binding", "id": "GO:0005160", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005160", "evidence": [ { "database": "UniProtKB", "id": "Q5UCE3", "url": "https://www.uniprot.org/uniprotkb/Q5UCE3" } ], "pmid": "" }, { "name": "growth factor activity", "id": "GO:0008083", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008083", "evidence": [ { "database": "UniProtKB", "id": "Q5UCE3", "url": "https://www.uniprot.org/uniprotkb/Q5UCE3" } ], "pmid": "" } ], "biological_process": [ { "name": "BMP signaling pathway", "id": "GO:0030509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030509", "evidence": [ { "database": "UniProtKB", "id": "Q5UCE3", "url": "https://www.uniprot.org/uniprotkb/Q5UCE3" } ], "pmid": "" }, { "name": "anterior/posterior axis specification", "id": "GO:0009948", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009948", "evidence": [ { "database": "UniProtKB", "id": "Q5UCE3", "url": "https://www.uniprot.org/uniprotkb/Q5UCE3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q5UCE3-1" }, { "uniprot_canonical_ac": "Q672J3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "Q672J3", "url": "https://www.uniprot.org/uniprotkb/Q672J3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 757, "chemical_mass": 86360.0, "gene_names": "Zbtb1;Zbtb1", "protein_name": "", "disease": [], "biological_process": [ { "name": "positive regulation of T cell mediated immunity", "id": "GO:0002711", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002711", "evidence": [ { "database": "UniProtKB", "id": "Q672J3", "url": "https://www.uniprot.org/uniprotkb/Q672J3" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "Q672J3", "url": "https://www.uniprot.org/uniprotkb/Q672J3" } ], "pmid": "" }, { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "Q672J3", "url": "https://www.uniprot.org/uniprotkb/Q672J3" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "Q672J3", "url": "https://www.uniprot.org/uniprotkb/Q672J3" } ], "pmid": "" }, { "name": "protein homooligomerization", "id": "GO:0051260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051260", "evidence": [ { "database": "UniProtKB", "id": "Q672J3", "url": "https://www.uniprot.org/uniprotkb/Q672J3" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "Q672J3", "url": "https://www.uniprot.org/uniprotkb/Q672J3" } ], "pmid": "" }, { "name": "thymus development", "id": "GO:0048538", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048538", "evidence": [ { "database": "UniProtKB", "id": "Q672J3", "url": "https://www.uniprot.org/uniprotkb/Q672J3" } ], "pmid": "" }, { "name": "B cell differentiation", "id": "GO:0030183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030183", "evidence": [ { "database": "UniProtKB", "id": "Q672J3", "url": "https://www.uniprot.org/uniprotkb/Q672J3" } ], "pmid": "" }, { "name": "T cell differentiation in thymus", "id": "GO:0033077", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033077", "evidence": [ { "database": "UniProtKB", "id": "Q672J3", "url": "https://www.uniprot.org/uniprotkb/Q672J3" } ], "pmid": "" }, { "name": "cellular response to UV", "id": "GO:0034644", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034644", "evidence": [ { "database": "UniProtKB", "id": "Q672J3", "url": "https://www.uniprot.org/uniprotkb/Q672J3" } ], "pmid": "" }, { "name": "mRNA transcription by RNA polymerase II", "id": "GO:0042789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042789", "evidence": [ { "database": "UniProtKB", "id": "Q672J3", "url": "https://www.uniprot.org/uniprotkb/Q672J3" } ], "pmid": "" }, { "name": "translesion synthesis", "id": "GO:0019985", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019985", "evidence": [ { "database": "UniProtKB", "id": "Q672J3", "url": "https://www.uniprot.org/uniprotkb/Q672J3" } ], "pmid": "" }, { "name": "positive regulation of pro-T cell differentiation", "id": "GO:2000176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000176", "evidence": [ { "database": "UniProtKB", "id": "Q672J3", "url": "https://www.uniprot.org/uniprotkb/Q672J3" } ], "pmid": "" }, { "name": "positive regulation of T cell differentiation", "id": "GO:0045582", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045582", "evidence": [ { "database": "UniProtKB", "id": "Q672J3", "url": "https://www.uniprot.org/uniprotkb/Q672J3" } ], "pmid": "" }, { "name": "positive regulation of natural killer cell differentiation", "id": "GO:0032825", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032825", "evidence": [ { "database": "UniProtKB", "id": "Q672J3", "url": "https://www.uniprot.org/uniprotkb/Q672J3" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q672J3", "url": "https://www.uniprot.org/uniprotkb/Q672J3" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "Q672J3", "url": "https://www.uniprot.org/uniprotkb/Q672J3" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "Q672J3", "url": "https://www.uniprot.org/uniprotkb/Q672J3" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "Q672J3", "url": "https://www.uniprot.org/uniprotkb/Q672J3" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q672J3", "url": "https://www.uniprot.org/uniprotkb/Q672J3" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "Q672J3", "url": "https://www.uniprot.org/uniprotkb/Q672J3" } ], "pmid": "" }, { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "Q672J3", "url": "https://www.uniprot.org/uniprotkb/Q672J3" } ], "pmid": "" }, { "name": "K63-linked polyubiquitin modification-dependent protein binding", "id": "GO:0070530", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070530", "evidence": [ { "database": "UniProtKB", "id": "Q672J3", "url": "https://www.uniprot.org/uniprotkb/Q672J3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q672J3-1" }, { "uniprot_canonical_ac": "Q67ER1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "Q67ER1", "url": "https://www.uniprot.org/uniprotkb/Q67ER1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 337, "chemical_mass": 38028.0, "gene_names": "Rnf113a2;Rnf113a2;Znf183", "protein_name": "", "disease": [ { "disease_id": "DOID:0111868", "name": "nonphotosensitive trichothiodystrophy 5", "description": "A nonphotosensitive trichothiodystrophy characterized by sparse and brittle hair, facial dysmorphism, global developmental delays, growth deficiency, hypogonadism, and structural brain abnormalities that has_material_basis_in hemizygous mutation in the RNF113A gene on chromosome Xq24.", "url": "https://disease-ontology.org/term/DOID:0111868", "evidence": [ { "id": "0111868", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111868" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q67ER1", "url": "https://www.uniprot.org/uniprotkb/Q67ER1" } ], "pmid": "" }, { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "Q67ER1", "url": "https://www.uniprot.org/uniprotkb/Q67ER1" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "Q67ER1", "url": "https://www.uniprot.org/uniprotkb/Q67ER1" } ], "pmid": "" } ], "cellular_component": [ { "name": "U2-type spliceosomal complex", "id": "GO:0005684", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005684", "evidence": [ { "database": "UniProtKB", "id": "Q67ER1", "url": "https://www.uniprot.org/uniprotkb/Q67ER1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q67ER1-1" }, { "uniprot_canonical_ac": "Q6MG00-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "Q6MG00", "url": "https://www.uniprot.org/uniprotkb/Q6MG00" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 181, "chemical_mass": 20331.0, "gene_names": "RT1-O1;Qlikea;RT1-O1;RT1-O", "protein_name": "", "disease": [], "biological_process": [ { "name": "antigen processing and presentation of peptide antigen via MHC class I", "id": "GO:0002474", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002474", "evidence": [ { "database": "UniProtKB", "id": "Q6MG00", "url": "https://www.uniprot.org/uniprotkb/Q6MG00" } ], "pmid": "" } ], "cellular_component": [ { "name": "phagocytic vesicle membrane", "id": "GO:0030670", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030670", "evidence": [ { "database": "UniProtKB", "id": "Q6MG00", "url": "https://www.uniprot.org/uniprotkb/Q6MG00" } ], "pmid": "" }, { "name": "MHC class I protein complex", "id": "GO:0042612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042612", "evidence": [ { "database": "UniProtKB", "id": "Q6MG00", "url": "https://www.uniprot.org/uniprotkb/Q6MG00" } ], "pmid": "" }, { "name": "lumenal side of endoplasmic reticulum membrane", "id": "GO:0098553", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098553", "evidence": [ { "database": "UniProtKB", "id": "Q6MG00", "url": "https://www.uniprot.org/uniprotkb/Q6MG00" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q6MG00-1" }, { "uniprot_canonical_ac": "Q6P4Z7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "Q6P4Z7", "url": "https://www.uniprot.org/uniprotkb/Q6P4Z7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 166, "chemical_mass": 17825.0, "gene_names": "Cdkn2d;Cdkn2d", "protein_name": "Cyclin-dependent kinase 4 inhibitor D", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6P4Z7", "url": "https://www.uniprot.org/uniprotkb/Q6P4Z7" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "Q6P4Z7", "url": "https://www.uniprot.org/uniprotkb/Q6P4Z7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6P4Z7", "url": "https://www.uniprot.org/uniprotkb/Q6P4Z7" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q6P4Z7", "url": "https://www.uniprot.org/uniprotkb/Q6P4Z7" } ], "pmid": "" }, { "name": "cyclin D2-CDK4 complex", "id": "GO:0097129", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097129", "evidence": [ { "database": "UniProtKB", "id": "Q6P4Z7", "url": "https://www.uniprot.org/uniprotkb/Q6P4Z7" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of cell population proliferation", "id": "GO:0008285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008285", "evidence": [ { "database": "UniProtKB", "id": "Q6P4Z7", "url": "https://www.uniprot.org/uniprotkb/Q6P4Z7" } ], "pmid": "" }, { "name": "negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage", "id": "GO:1902230", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902230", "evidence": [ { "database": "UniProtKB", "id": "Q6P4Z7", "url": "https://www.uniprot.org/uniprotkb/Q6P4Z7" } ], "pmid": "" }, { "name": "response to retinoic acid", "id": "GO:0032526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032526", "evidence": [ { "database": "UniProtKB", "id": "Q6P4Z7", "url": "https://www.uniprot.org/uniprotkb/Q6P4Z7" } ], "pmid": "" }, { "name": "negative regulation of cell growth", "id": "GO:0030308", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030308", "evidence": [ { "database": "UniProtKB", "id": "Q6P4Z7", "url": "https://www.uniprot.org/uniprotkb/Q6P4Z7" } ], "pmid": "" }, { "name": "response to UV", "id": "GO:0009411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009411", "evidence": [ { "database": "UniProtKB", "id": "Q6P4Z7", "url": "https://www.uniprot.org/uniprotkb/Q6P4Z7" } ], "pmid": "" }, { "name": "sensory perception of sound", "id": "GO:0007605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007605", "evidence": [ { "database": "UniProtKB", "id": "Q6P4Z7", "url": "https://www.uniprot.org/uniprotkb/Q6P4Z7" } ], "pmid": "" }, { "name": "negative regulation of G1/S transition of mitotic cell cycle", "id": "GO:2000134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000134", "evidence": [ { "database": "UniProtKB", "id": "Q6P4Z7", "url": "https://www.uniprot.org/uniprotkb/Q6P4Z7" } ], "pmid": "" }, { "name": "response to vitamin D", "id": "GO:0033280", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033280", "evidence": [ { "database": "UniProtKB", "id": "Q6P4Z7", "url": "https://www.uniprot.org/uniprotkb/Q6P4Z7" } ], "pmid": "" }, { "name": "DNA synthesis involved in DNA repair", "id": "GO:0000731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000731", "evidence": [ { "database": "UniProtKB", "id": "Q6P4Z7", "url": "https://www.uniprot.org/uniprotkb/Q6P4Z7" } ], "pmid": "" }, { "name": "regulation of G1/S transition of mitotic cell cycle", "id": "GO:2000045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000045", "evidence": [ { "database": "UniProtKB", "id": "Q6P4Z7", "url": "https://www.uniprot.org/uniprotkb/Q6P4Z7" } ], "pmid": "" }, { "name": "autophagic cell death", "id": "GO:0048102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048102", "evidence": [ { "database": "UniProtKB", "id": "Q6P4Z7", "url": "https://www.uniprot.org/uniprotkb/Q6P4Z7" } ], "pmid": "" }, { "name": "negative regulation of cell cycle G1/S phase transition", "id": "GO:1902807", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902807", "evidence": [ { "database": "UniProtKB", "id": "Q6P4Z7", "url": "https://www.uniprot.org/uniprotkb/Q6P4Z7" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "Q6P4Z7", "url": "https://www.uniprot.org/uniprotkb/Q6P4Z7" } ], "pmid": "" }, { "name": "cyclin-dependent protein serine/threonine kinase inhibitor activity", "id": "GO:0004861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004861", "evidence": [ { "database": "UniProtKB", "id": "Q6P4Z7", "url": "https://www.uniprot.org/uniprotkb/Q6P4Z7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q6P4Z7-1" }, { "uniprot_canonical_ac": "Q6QI29-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "Q6QI29", "url": "https://www.uniprot.org/uniprotkb/Q6QI29" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 111, "chemical_mass": 12633.0, "gene_names": "", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q6QI29-1" }, { "uniprot_canonical_ac": "Q76M99-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "Q76M99", "url": "https://www.uniprot.org/uniprotkb/Q76M99" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 551, "chemical_mass": 60981.0, "gene_names": "Slc22a24;Oat5;Slc22a19;Slc22a24;Slc22a9;rOat5", "protein_name": "Steroid transmembrane transporter SLC22A24", "disease": [ { "disease_id": "DOID:0112182", "name": "mismatch repair cancer syndrome", "description": "A syndrome characterized by predisposition for development of a broad spectrum of malignancies during childhood, including mainly brain, hematological and gastrointestinal cancers that has_material_basis_in homozygous or compound heterozygous mutation in the mismatch repair genes MLH1, MSH2, MSH6, or PMS2 on chromosomes 3p22.2, 2p21-p16, 2p16.3, and 7p22.1, respectively.", "url": "https://disease-ontology.org/term/DOID:0112182", "evidence": [ { "id": "0112182", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112182" } ], "weight": 0.0 }, { "disease_id": "DOID:3883", "name": "Lynch syndrome", "description": "A syndrome that is characterized by an increased risk for colon cancer and cancers of the endometrium, ovary, stomach, small intestine, hepatobiliary tract, urinary tract, brain, and skin and has_material_basis_in mutation of mismatch repair genes that increases the risk of many types of cancers.", "url": "https://disease-ontology.org/term/DOID:3883", "evidence": [ { "id": "3883", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3883" } ], "weight": 0.0 } ], "biological_process": [ { "name": "monoatomic ion transport", "id": "GO:0006811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006811", "evidence": [ { "database": "UniProtKB", "id": "Q76M99", "url": "https://www.uniprot.org/uniprotkb/Q76M99" } ], "pmid": "" }, { "name": "organic anion transport", "id": "GO:0015711", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015711", "evidence": [ { "database": "UniProtKB", "id": "Q76M99", "url": "https://www.uniprot.org/uniprotkb/Q76M99" } ], "pmid": "" }, { "name": "sodium-independent organic anion transport", "id": "GO:0043252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043252", "evidence": [ { "database": "UniProtKB", "id": "Q76M99", "url": "https://www.uniprot.org/uniprotkb/Q76M99" } ], "pmid": "" }, { "name": "steroid metabolic process", "id": "GO:0008202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008202", "evidence": [ { "database": "UniProtKB", "id": "Q76M99", "url": "https://www.uniprot.org/uniprotkb/Q76M99" } ], "pmid": "" }, { "name": "response to molecule of fungal origin", "id": "GO:0002238", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002238", "evidence": [ { "database": "UniProtKB", "id": "Q76M99", "url": "https://www.uniprot.org/uniprotkb/Q76M99" } ], "pmid": "" }, { "name": "sterol transmembrane transport", "id": "GO:0035382", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035382", "evidence": [ { "database": "UniProtKB", "id": "Q76M99", "url": "https://www.uniprot.org/uniprotkb/Q76M99" } ], "pmid": "" } ], "molecular_function": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "Q76M99", "url": "https://www.uniprot.org/uniprotkb/Q76M99" } ], "pmid": "" }, { "name": "toxin transmembrane transporter activity", "id": "GO:0019534", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019534", "evidence": [ { "database": "UniProtKB", "id": "Q76M99", "url": "https://www.uniprot.org/uniprotkb/Q76M99" } ], "pmid": "" } ], "cellular_component": [ { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "Q76M99", "url": "https://www.uniprot.org/uniprotkb/Q76M99" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q76M99-1" }, { "uniprot_canonical_ac": "Q7TNA8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "Q7TNA8", "url": "https://www.uniprot.org/uniprotkb/Q7TNA8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 382, "chemical_mass": 42049.0, "gene_names": "Ldhal6b;Ldhal6b;Ldhl", "protein_name": "L-lactate dehydrogenase", "disease": [ { "disease_id": "DOID:0014667", "name": "disease of metabolism", "description": "A disease that involves errors in metabolic processes of building or degradation of molecules.", "url": "https://disease-ontology.org/term/DOID:0014667", "evidence": [ { "id": "0014667", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0014667" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q7TNA8", "url": "https://www.uniprot.org/uniprotkb/Q7TNA8" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q7TNA8", "url": "https://www.uniprot.org/uniprotkb/Q7TNA8" } ], "pmid": "" } ], "molecular_function": [ { "name": "NAD binding", "id": "GO:0051287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051287", "evidence": [ { "database": "UniProtKB", "id": "Q7TNA8", "url": "https://www.uniprot.org/uniprotkb/Q7TNA8" } ], "pmid": "" }, { "name": "L-lactate dehydrogenase (NAD+) activity", "id": "GO:0004459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004459", "evidence": [ { "database": "UniProtKB", "id": "Q7TNA8", "url": "https://www.uniprot.org/uniprotkb/Q7TNA8" } ], "pmid": "" } ], "biological_process": [ { "name": "NAD+ metabolic process", "id": "GO:0019674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019674", "evidence": [ { "database": "UniProtKB", "id": "Q7TNA8", "url": "https://www.uniprot.org/uniprotkb/Q7TNA8" } ], "pmid": "" }, { "name": "lactate metabolic process", "id": "GO:0006089", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006089", "evidence": [ { "database": "UniProtKB", "id": "Q7TNA8", "url": "https://www.uniprot.org/uniprotkb/Q7TNA8" } ], "pmid": "" }, { "name": "pyruvate catabolic process", "id": "GO:0042867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042867", "evidence": [ { "database": "UniProtKB", "id": "Q7TNA8", "url": "https://www.uniprot.org/uniprotkb/Q7TNA8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q7TNA8-1" }, { "uniprot_canonical_ac": "Q80ZF4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "Q80ZF4", "url": "https://www.uniprot.org/uniprotkb/Q80ZF4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 386, "chemical_mass": 44036.0, "gene_names": "Mapkapk2;Mapkapk2", "protein_name": "non-specific serine/threonine protein kinase", "disease": [], "molecular_function": [ { "name": "calcium-dependent protein serine/threonine kinase activity", "id": "GO:0009931", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009931", "evidence": [ { "database": "UniProtKB", "id": "Q80ZF4", "url": "https://www.uniprot.org/uniprotkb/Q80ZF4" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "Q80ZF4", "url": "https://www.uniprot.org/uniprotkb/Q80ZF4" } ], "pmid": "" }, { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "Q80ZF4", "url": "https://www.uniprot.org/uniprotkb/Q80ZF4" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q80ZF4", "url": "https://www.uniprot.org/uniprotkb/Q80ZF4" } ], "pmid": "" }, { "name": "mitogen-activated protein kinase binding", "id": "GO:0051019", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051019", "evidence": [ { "database": "UniProtKB", "id": "Q80ZF4", "url": "https://www.uniprot.org/uniprotkb/Q80ZF4" } ], "pmid": "" }, { "name": "calcium/calmodulin-dependent protein kinase activity", "id": "GO:0004683", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004683", "evidence": [ { "database": "UniProtKB", "id": "Q80ZF4", "url": "https://www.uniprot.org/uniprotkb/Q80ZF4" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q80ZF4", "url": "https://www.uniprot.org/uniprotkb/Q80ZF4" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "Q80ZF4", "url": "https://www.uniprot.org/uniprotkb/Q80ZF4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q80ZF4", "url": "https://www.uniprot.org/uniprotkb/Q80ZF4" } ], "pmid": "" } ], "biological_process": [ { "name": "protein phosphorylation", "id": "GO:0006468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006468", "evidence": [ { "database": "UniProtKB", "id": "Q80ZF4", "url": "https://www.uniprot.org/uniprotkb/Q80ZF4" } ], "pmid": "" }, { "name": "inflammatory response", "id": "GO:0006954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006954", "evidence": [ { "database": "UniProtKB", "id": "Q80ZF4", "url": "https://www.uniprot.org/uniprotkb/Q80ZF4" } ], "pmid": "" }, { "name": "response to lipopolysaccharide", "id": "GO:0032496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032496", "evidence": [ { "database": "UniProtKB", "id": "Q80ZF4", "url": "https://www.uniprot.org/uniprotkb/Q80ZF4" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "Q80ZF4", "url": "https://www.uniprot.org/uniprotkb/Q80ZF4" } ], "pmid": "" }, { "name": "mRNA stabilization", "id": "GO:0048255", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048255", "evidence": [ { "database": "UniProtKB", "id": "Q80ZF4", "url": "https://www.uniprot.org/uniprotkb/Q80ZF4" } ], "pmid": "" }, { "name": "MAPK cascade", "id": "GO:0000165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000165", "evidence": [ { "database": "UniProtKB", "id": "Q80ZF4", "url": "https://www.uniprot.org/uniprotkb/Q80ZF4" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "Q80ZF4", "url": "https://www.uniprot.org/uniprotkb/Q80ZF4" } ], "pmid": "" }, { "name": "regulation of interleukin-6 production", "id": "GO:0032675", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032675", "evidence": [ { "database": "UniProtKB", "id": "Q80ZF4", "url": "https://www.uniprot.org/uniprotkb/Q80ZF4" } ], "pmid": "" }, { "name": "response to cytokine", "id": "GO:0034097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034097", "evidence": [ { "database": "UniProtKB", "id": "Q80ZF4", "url": "https://www.uniprot.org/uniprotkb/Q80ZF4" } ], "pmid": "" }, { "name": "positive regulation of tumor necrosis factor production", "id": "GO:0032760", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032760", "evidence": [ { "database": "UniProtKB", "id": "Q80ZF4", "url": "https://www.uniprot.org/uniprotkb/Q80ZF4" } ], "pmid": "" }, { "name": "vascular endothelial growth factor receptor signaling pathway", "id": "GO:0048010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048010", "evidence": [ { "database": "UniProtKB", "id": "Q80ZF4", "url": "https://www.uniprot.org/uniprotkb/Q80ZF4" } ], "pmid": "" }, { "name": "inner ear development", "id": "GO:0048839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048839", "evidence": [ { "database": "UniProtKB", "id": "Q80ZF4", "url": "https://www.uniprot.org/uniprotkb/Q80ZF4" } ], "pmid": "" }, { "name": "3'-UTR-mediated mRNA stabilization", "id": "GO:0070935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070935", "evidence": [ { "database": "UniProtKB", "id": "Q80ZF4", "url": "https://www.uniprot.org/uniprotkb/Q80ZF4" } ], "pmid": "" }, { "name": "cellular response to vascular endothelial growth factor stimulus", "id": "GO:0035924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035924", "evidence": [ { "database": "UniProtKB", "id": "Q80ZF4", "url": "https://www.uniprot.org/uniprotkb/Q80ZF4" } ], "pmid": "" }, { "name": "toll-like receptor signaling pathway", "id": "GO:0002224", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002224", "evidence": [ { "database": "UniProtKB", "id": "Q80ZF4", "url": "https://www.uniprot.org/uniprotkb/Q80ZF4" } ], "pmid": "" }, { "name": "regulation of tumor necrosis factor production", "id": "GO:0032680", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032680", "evidence": [ { "database": "UniProtKB", "id": "Q80ZF4", "url": "https://www.uniprot.org/uniprotkb/Q80ZF4" } ], "pmid": "" }, { "name": "macropinocytosis", "id": "GO:0044351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044351", "evidence": [ { "database": "UniProtKB", "id": "Q80ZF4", "url": "https://www.uniprot.org/uniprotkb/Q80ZF4" } ], "pmid": "" }, { "name": "p38MAPK cascade", "id": "GO:0038066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038066", "evidence": [ { "database": "UniProtKB", "id": "Q80ZF4", "url": "https://www.uniprot.org/uniprotkb/Q80ZF4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q80ZF4-1" }, { "uniprot_canonical_ac": "A0A0G2JZJ1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JZJ1", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JZJ1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 310, "chemical_mass": 34577.0, "gene_names": "Psmd14;Psmd14", "protein_name": "Ubiquitin C-terminal hydrolase PSMD14", "disease": [ { "disease_id": "DOID:0070658", "name": "alcohol-associated liver disease", "description": "A liver disease resulting from excessive alcohol intake.", "url": "https://disease-ontology.org/term/DOID:0070658", "evidence": [ { "id": "0070658", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070658" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytosolic proteasome complex", "id": "GO:0031597", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031597", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JZJ1", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JZJ1" } ], "pmid": "" }, { "name": "proteasome accessory complex", "id": "GO:0022624", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022624", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JZJ1", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JZJ1" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JZJ1", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JZJ1" } ], "pmid": "" }, { "name": "proteasome complex", "id": "GO:0000502", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000502", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JZJ1", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JZJ1" } ], "pmid": "" }, { "name": "proteasome regulatory particle, lid subcomplex", "id": "GO:0008541", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008541", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JZJ1", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JZJ1" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JZJ1", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JZJ1" } ], "pmid": "" }, { "name": "response to ethanol", "id": "GO:0045471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045471", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JZJ1", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JZJ1" } ], "pmid": "" }, { "name": "protein K63-linked deubiquitination", "id": "GO:0070536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070536", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JZJ1", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JZJ1" } ], "pmid": "" }, { "name": "regulation of macroautophagy", "id": "GO:0016241", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016241", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JZJ1", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JZJ1" } ], "pmid": "" }, { "name": "double-strand break repair via nonhomologous end joining", "id": "GO:0006303", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006303", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JZJ1", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JZJ1" } ], "pmid": "" }, { "name": "retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum", "id": "GO:0006890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006890", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JZJ1", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JZJ1" } ], "pmid": "" }, { "name": "double-strand break repair via homologous recombination", "id": "GO:0000724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000724", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JZJ1", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JZJ1" } ], "pmid": "" }, { "name": "regulation of proteasomal protein catabolic process", "id": "GO:0061136", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061136", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JZJ1", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JZJ1" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JZJ1", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JZJ1" } ], "pmid": "" }, { "name": "endopeptidase activator activity", "id": "GO:0061133", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061133", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JZJ1", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JZJ1" } ], "pmid": "" }, { "name": "proteasome binding", "id": "GO:0070628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070628", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JZJ1", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JZJ1" } ], "pmid": "" }, { "name": "K63-linked deubiquitinase activity", "id": "GO:0061578", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061578", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JZJ1", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JZJ1" } ], "pmid": "" }, { "name": "metal-dependent deubiquitinase activity", "id": "GO:0140492", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140492", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JZJ1", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JZJ1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A0G2JZJ1-1" }, { "uniprot_canonical_ac": "A0A0G2K6F4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K6F4", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K6F4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 894, "chemical_mass": 101657.0, "gene_names": "Extl3", "protein_name": "Exostosin-like 3", "disease": [ { "disease_id": "DOID:206", "name": "hereditary multiple exostoses", "description": "An exostosis that has_material_basis_in a mutation on the genes EXT1, EXT2 and EXT3 which results in multiple bony spurs throughout a child's growth.", "url": "https://disease-ontology.org/term/DOID:206", "evidence": [ { "id": "206", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:206" } ], "weight": 0.0 } ], "biological_process": [ { "name": "negative regulation of keratinocyte differentiation", "id": "GO:0045617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045617", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K6F4", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K6F4" } ], "pmid": "" }, { "name": "positive regulation of cell growth", "id": "GO:0030307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030307", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K6F4", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K6F4" } ], "pmid": "" }, { "name": "positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction", "id": "GO:0051897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051897", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K6F4", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K6F4" } ], "pmid": "" }, { "name": "negative regulation of inflammatory response", "id": "GO:0050728", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050728", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K6F4", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K6F4" } ], "pmid": "" }, { "name": "negative regulation of cytokine production involved in inflammatory response", "id": "GO:1900016", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900016", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K6F4", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K6F4" } ], "pmid": "" }, { "name": "heparan sulfate proteoglycan biosynthetic process", "id": "GO:0015012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015012", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K6F4", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K6F4" } ], "pmid": "" }, { "name": "positive regulation of keratinocyte proliferation", "id": "GO:0010838", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010838", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K6F4", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K6F4" } ], "pmid": "" }, { "name": "negative regulation of inflammatory response to wounding", "id": "GO:0106015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106015", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K6F4", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K6F4" } ], "pmid": "" }, { "name": "positive regulation of detection of glucose", "id": "GO:2000972", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000972", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K6F4", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K6F4" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-hormone receptor activity", "id": "GO:0016500", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016500", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K6F4", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K6F4" } ], "pmid": "" }, { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K6F4", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K6F4" } ], "pmid": "" }, { "name": "glycosyltransferase activity", "id": "GO:0016757", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016757", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K6F4", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K6F4" } ], "pmid": "" }, { "name": "glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity", "id": "GO:0001888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001888", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K6F4", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K6F4" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K6F4", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K6F4" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K6F4", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K6F4" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K6F4", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K6F4" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K6F4", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K6F4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A0G2K6F4-1" }, { "uniprot_canonical_ac": "A0A0G2K6V2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K6V2", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K6V2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1560, "chemical_mass": 178330.0, "gene_names": "Kdm5d;Jarid1d;Kdm5d", "protein_name": "[histone H3]-trimethyl-L-lysine(4) demethylase", "disease": [ { "disease_id": "DOID:0050888", "name": "syndromic intellectual disability", "description": "An intellectual disability that is characterized by the presence of associated medical and behavioral sign and symptoms.", "url": "https://disease-ontology.org/term/DOID:0050888", "evidence": [ { "id": "0050888", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050888" } ], "weight": 0.0 }, { "disease_id": "DOID:0060041", "name": "autism spectrum disorder", "description": "A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior.", "url": "https://disease-ontology.org/term/DOID:0060041", "evidence": [ { "id": "0060041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060041" } ], "weight": 0.0 }, { "disease_id": "DOID:0060809", "name": "syndromic X-linked intellectual disability Claes-Jensen type", "description": "A syndromic X-linked intellectual disability characterized by severe intellectual deficit associated with variable clinical manifestations including spasticity, cryptorchidism, maxillary hypoplasia, alopecia areata, epilepsy, short stature, impaired speech and behavioral problems that has_material_basis_in mutation in the KDM5C gene on chromosome Xp11.", "url": "https://disease-ontology.org/term/DOID:0060809", "evidence": [ { "id": "0060809", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060809" } ], "weight": 0.0 }, { "disease_id": "DOID:1059", "name": "intellectual disability", "description": "A specific developmental disorder that involves significant limitations both in mental functioning and in adaptive behavior such as communicating, taking care of him or herself, and social skills.", "url": "https://disease-ontology.org/term/DOID:1059", "evidence": [ { "id": "1059", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1059" } ], "weight": 0.0 }, { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "histone H3K4me/H3K4me2/H3K4me3 demethylase activity", "id": "GO:0034647", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034647", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K6V2", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K6V2" } ], "pmid": "" }, { "name": "histone H3K4 demethylase activity", "id": "GO:0032453", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032453", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K6V2", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K6V2" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K6V2", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K6V2" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K6V2", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K6V2" } ], "pmid": "" }, { "name": "nuclear androgen receptor binding", "id": "GO:0050681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050681", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K6V2", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K6V2" } ], "pmid": "" } ], "biological_process": [ { "name": "T cell antigen processing and presentation", "id": "GO:0002457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002457", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K6V2", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K6V2" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K6V2", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K6V2" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K6V2", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K6V2" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K6V2", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K6V2" } ], "pmid": "" }, { "name": "regulation of androgen receptor signaling pathway", "id": "GO:0060765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060765", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K6V2", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K6V2" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K6V2", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K6V2" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K6V2", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K6V2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A0G2K6V2-1" }, { "uniprot_canonical_ac": "A0A0G2K7V2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K7V2", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K7V2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 472, "chemical_mass": 52005.0, "gene_names": "Gsdmdl1;Gsdmdl1;RGD1359449", "protein_name": "", "disease": [], "molecular_function": [ { "name": "phosphatidylinositol-4,5-bisphosphate binding", "id": "GO:0005546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005546", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K7V2", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K7V2" } ], "pmid": "" }, { "name": "phosphatidylinositol-4-phosphate binding", "id": "GO:0070273", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070273", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K7V2", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K7V2" } ], "pmid": "" }, { "name": "phosphatidylserine binding", "id": "GO:0001786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001786", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K7V2", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K7V2" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K7V2", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K7V2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K7V2", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K7V2" } ], "pmid": "" } ], "biological_process": [ { "name": "defense response to bacterium", "id": "GO:0042742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042742", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K7V2", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K7V2" } ], "pmid": "" }, { "name": "pyroptotic inflammatory response", "id": "GO:0070269", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070269", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K7V2", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K7V2" } ], "pmid": "" }, { "name": "programmed cell death", "id": "GO:0012501", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012501", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K7V2", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K7V2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A0G2K7V2-1" }, { "uniprot_canonical_ac": "A0A8I5XUU3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XUU3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XUU3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 322, "chemical_mass": 36086.0, "gene_names": "ENSRNOG00000069029", "protein_name": "Ig-like domain-containing protein", "disease": [], "biological_process": [ { "name": "immune response-inhibiting cell surface receptor signaling pathway", "id": "GO:0002767", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002767", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XUU3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XUU3" } ], "pmid": "" }, { "name": "cytokine-mediated signaling pathway", "id": "GO:0019221", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019221", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XUU3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XUU3" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XUU3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XUU3" } ], "pmid": "" } ], "molecular_function": [ { "name": "inhibitory MHC class I receptor activity", "id": "GO:0032396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032396", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XUU3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XUU3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5XUU3-1" }, { "uniprot_canonical_ac": "A0A8I5XVG9-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XVG9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XVG9" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 147, "chemical_mass": 16466.0, "gene_names": "ENSRNOG00000065366;Rps16-ps7", "protein_name": "Small ribosomal subunit protein uS9", "disease": [], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XVG9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XVG9" } ], "pmid": "" }, { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XVG9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XVG9" } ], "pmid": "" } ], "biological_process": [ { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XVG9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XVG9" } ], "pmid": "" }, { "name": "maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000462", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000462", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XVG9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XVG9" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosolic small ribosomal subunit", "id": "GO:0022627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022627", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XVG9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XVG9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5XVG9-1" }, { "uniprot_canonical_ac": "A0A8I5XWI7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XWI7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XWI7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 407, "chemical_mass": 46123.0, "gene_names": "Aadacl4fm3;AAdacl4fm3;RGD1559644", "protein_name": "", "disease": [], "molecular_function": [ { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XWI7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XWI7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5XWI7-1" }, { "uniprot_canonical_ac": "A0A8I5XWP3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XWP3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XWP3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 127, "chemical_mass": 14238.0, "gene_names": "ENSRNOG00000063695", "protein_name": "Ig-like domain-containing protein", "disease": [], "cellular_component": [ { "name": "T cell receptor complex", "id": "GO:0042101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042101", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XWP3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XWP3" } ], "pmid": "" } ], "biological_process": [ { "name": "adaptive immune response", "id": "GO:0002250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002250", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XWP3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XWP3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5XWP3-1" }, { "uniprot_canonical_ac": "A0A8I5Y806-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y806", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y806" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 138, "chemical_mass": 15553.0, "gene_names": "Igkvl13", "protein_name": "", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y806", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y806" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y806", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y806" } ], "pmid": "" }, { "name": "immunoglobulin complex", "id": "GO:0019814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019814", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y806", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y806" } ], "pmid": "" } ], "biological_process": [ { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y806", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y806" } ], "pmid": "" }, { "name": "adaptive immune response", "id": "GO:0002250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002250", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y806", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y806" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5Y806-1" }, { "uniprot_canonical_ac": "A0A8I5ZJD4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZJD4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZJD4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 623, "chemical_mass": 64624.0, "gene_names": "Zic5;Zic5", "protein_name": "Zinc finger protein ZIC 5", "disease": [ { "disease_id": "DOID:4621", "name": "holoprosencephaly", "description": "A congenital nervous system abnormality characterized by failed or incomplete separation of the forebrain early in gestation; it is accompanied by a spectrum of characteristic craniofacial anomalies.", "url": "https://disease-ontology.org/term/DOID:4621", "evidence": [ { "id": "4621", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4621" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZJD4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZJD4" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZJD4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZJD4" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZJD4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZJD4" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZJD4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZJD4" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZJD4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZJD4" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZJD4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZJD4" } ], "pmid": "" }, { "name": "sequence-specific double-stranded DNA binding", "id": "GO:1990837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990837", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZJD4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZJD4" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZJD4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZJD4" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZJD4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZJD4" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZJD4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZJD4" } ], "pmid": "" }, { "name": "forebrain development", "id": "GO:0030900", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030900", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZJD4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZJD4" } ], "pmid": "" }, { "name": "central nervous system development", "id": "GO:0007417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007417", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZJD4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZJD4" } ], "pmid": "" }, { "name": "neural tube closure", "id": "GO:0001843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001843", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZJD4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZJD4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZJD4-1" }, { "uniprot_canonical_ac": "A0A8I5ZKN2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZKN2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZKN2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 203, "chemical_mass": 22497.0, "gene_names": "Pgpep1l", "protein_name": "", "disease": [], "molecular_function": [ { "name": "pyroglutamyl-peptidase activity", "id": "GO:0016920", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016920", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZKN2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZKN2" } ], "pmid": "" }, { "name": "peptidase activity", "id": "GO:0008233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008233", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZKN2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZKN2" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZKN2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZKN2" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZKN2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZKN2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZKN2-1" }, { "uniprot_canonical_ac": "A0A8I5ZKT7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZKT7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZKT7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 99, "chemical_mass": 10708.0, "gene_names": "ENSRNOG00000063576", "protein_name": "LIM zinc-binding domain-containing protein", "disease": [], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZKT7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZKT7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZKT7-1" }, { "uniprot_canonical_ac": "A0A8I5ZL05-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZL05", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZL05" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 316, "chemical_mass": 35192.0, "gene_names": "Or8c11", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZL05", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZL05" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZL05", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZL05" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZL05", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZL05" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZL05", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZL05" } ], "pmid": "" } ], "biological_process": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZL05", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZL05" } ], "pmid": "" }, { "name": "sensory perception of smell", "id": "GO:0007608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007608", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZL05", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZL05" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I5ZL05-1", "start_pos": "269", "end_pos": "269", "site_lbl": "Thr269", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 269, "start_aa": "Thr", "end_pos": 269, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr269", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I5ZL05-1" }, { "uniprot_canonical_ac": "A0A8I5ZL18-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZL18", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZL18" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 120, "chemical_mass": 13521.0, "gene_names": "AABR07017768.6", "protein_name": "Ig-like domain-containing protein", "disease": [], "cellular_component": [ { "name": "T cell receptor complex", "id": "GO:0042101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042101", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZL18", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZL18" } ], "pmid": "" } ], "biological_process": [ { "name": "adaptive immune response", "id": "GO:0002250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002250", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZL18", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZL18" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZL18-1" }, { "uniprot_canonical_ac": "A0A8I5ZL55-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZL55", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZL55" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 309, "chemical_mass": 34360.0, "gene_names": "Plekha3", "protein_name": "Sesquipedalian", "disease": [], "cellular_component": [ { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZL55", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZL55" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZL55", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZL55" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZL55", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZL55" } ], "pmid": "" }, { "name": "recycling endosome", "id": "GO:0055037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055037", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZL55", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZL55" } ], "pmid": "" }, { "name": "clathrin-coated vesicle", "id": "GO:0030136", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030136", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZL55", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZL55" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZL55", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZL55" } ], "pmid": "" } ], "molecular_function": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZL55", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZL55" } ], "pmid": "" }, { "name": "phosphatidylinositol-4-phosphate binding", "id": "GO:0070273", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070273", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZL55", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZL55" } ], "pmid": "" }, { "name": "molecular carrier activity", "id": "GO:0140104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140104", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZL55", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZL55" } ], "pmid": "" } ], "biological_process": [ { "name": "endosome organization", "id": "GO:0007032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007032", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZL55", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZL55" } ], "pmid": "" }, { "name": "receptor recycling", "id": "GO:0001881", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001881", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZL55", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZL55" } ], "pmid": "" }, { "name": "retrograde transport, endosome to Golgi", "id": "GO:0042147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042147", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZL55", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZL55" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZL55-1" }, { "uniprot_canonical_ac": "A0A8I6AD67-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AD67", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AD67" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 930, "chemical_mass": 103115.0, "gene_names": "Parp9;Parp9;RGD1307534", "protein_name": "", "disease": [], "biological_process": [ { "name": "positive regulation of cytokine-mediated signaling pathway", "id": "GO:0001961", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001961", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AD67", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AD67" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AD67", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AD67" } ], "pmid": "" }, { "name": "regulation of type II interferon-mediated signaling pathway", "id": "GO:0060334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060334", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AD67", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AD67" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AD67", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AD67" } ], "pmid": "" }, { "name": "negative regulation of gene expression", "id": "GO:0010629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010629", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AD67", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AD67" } ], "pmid": "" }, { "name": "post-transcriptional regulation of gene expression", "id": "GO:0010608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010608", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AD67", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AD67" } ], "pmid": "" }, { "name": "negative regulation of catalytic activity", "id": "GO:0043086", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043086", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AD67", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AD67" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AD67", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AD67" } ], "pmid": "" }, { "name": "double-strand break repair", "id": "GO:0006302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006302", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AD67", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AD67" } ], "pmid": "" }, { "name": "positive regulation of defense response to virus by host", "id": "GO:0002230", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002230", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AD67", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AD67" } ], "pmid": "" }, { "name": "positive regulation of protein localization to nucleus", "id": "GO:1900182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900182", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AD67", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AD67" } ], "pmid": "" }, { "name": "positive regulation of tyrosine phosphorylation of STAT protein", "id": "GO:0042531", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042531", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AD67", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AD67" } ], "pmid": "" }, { "name": "DNA damage checkpoint signaling", "id": "GO:0000077", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000077", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AD67", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AD67" } ], "pmid": "" }, { "name": "regulation of response to type II interferon", "id": "GO:0060330", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060330", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AD67", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AD67" } ], "pmid": "" }, { "name": "positive regulation of type II interferon-mediated signaling pathway", "id": "GO:0060335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060335", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AD67", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AD67" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AD67", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AD67" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AD67", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AD67" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AD67", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AD67" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AD67", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AD67" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AD67", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AD67" } ], "pmid": "" }, { "name": "site of DNA damage", "id": "GO:0090734", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090734", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AD67", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AD67" } ], "pmid": "" } ], "molecular_function": [ { "name": "nucleotidyltransferase activity", "id": "GO:0016779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016779", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AD67", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AD67" } ], "pmid": "" }, { "name": "NAD+ poly-ADP-ribosyltransferase activity", "id": "GO:0003950", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003950", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AD67", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AD67" } ], "pmid": "" }, { "name": "STAT family protein binding", "id": "GO:0097677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097677", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AD67", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AD67" } ], "pmid": "" }, { "name": "enzyme inhibitor activity", "id": "GO:0004857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004857", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AD67", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AD67" } ], "pmid": "" }, { "name": "enzyme binding", "id": "GO:0019899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019899", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AD67", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AD67" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AD67", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AD67" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AD67", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AD67" } ], "pmid": "" }, { "name": "ubiquitin-like protein ligase binding", "id": "GO:0044389", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044389", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AD67", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AD67" } ], "pmid": "" }, { "name": "ADP-D-ribose binding", "id": "GO:0072570", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072570", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AD67", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AD67" } ], "pmid": "" }, { "name": "NAD+-protein-C-terminal glycine ADP-ribosyltransferase activity", "id": "GO:0140802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140802", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AD67", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AD67" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6AD67-1", "start_pos": "249", "end_pos": "249", "site_lbl": "Thr249", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 249, "start_aa": "Thr", "end_pos": 249, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr249", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I6AD67-1", "start_pos": "350", "end_pos": "350", "site_lbl": "Thr350", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 350, "start_aa": "Thr", "end_pos": 350, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr350", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I6AD67-1", "start_pos": "869", "end_pos": "869", "site_lbl": "Ser869", "weight": 0.0, "snv": [ { "sequence_org": "S", "sequence_mut": "N", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (SVS->NVS).", "chr_id": "11", "chr_pos": "78286848", "evidence": [ { "id": "rs8166057", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs8166057" } ] } ] } ], "record_id": "A0A8I6AD67-1" }, { "uniprot_canonical_ac": "A0A8I5ZMT8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMT8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMT8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 117, "chemical_mass": 12827.0, "gene_names": "ENSRNOG00000063035", "protein_name": "Ig-like domain-containing protein", "disease": [], "biological_process": [ { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMT8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMT8" } ], "pmid": "" } ], "cellular_component": [ { "name": "immunoglobulin complex", "id": "GO:0019814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019814", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMT8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMT8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZMT8-1" }, { "uniprot_canonical_ac": "A0A8I5ZQ36-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQ36", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQ36" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 224, "chemical_mass": 26130.0, "gene_names": "Rgl4;RGD1559508", "protein_name": "", "disease": [], "molecular_function": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQ36", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQ36" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZQ36-1" }, { "uniprot_canonical_ac": "A0A8I5ZQ59-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQ59", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQ59" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 836, "chemical_mass": 94982.0, "gene_names": "Zfp27", "protein_name": "Zinc finger protein 585B", "disease": [], "biological_process": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQ59", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQ59" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQ59", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQ59" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQ59", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQ59" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQ59", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQ59" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQ59", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQ59" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZQ59-1" }, { "uniprot_canonical_ac": "A0A8I5ZQE9-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQE9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQE9" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 398, "chemical_mass": 44149.0, "gene_names": "Irf9;Irf9;Isgf3g", "protein_name": "Interferon regulatory factor 9", "disease": [ { "disease_id": "DOID:0111978", "name": "immunodeficiency 65", "description": "A primary immunodeficiency disease characterized by onset in early infancy of recurrent and severe viral infections, impaired cellular type I interferon response, and poor outcomes after vaccination with live attenuated vaccines that has_material_basis_in homozygous or compound heterozygous mutation in the IRF9 gene on chromosome 14q12.", "url": "https://disease-ontology.org/term/DOID:0111978", "evidence": [ { "id": "0111978", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111978" } ], "weight": 0.0 }, { "disease_id": "DOID:1168", "name": "familial hyperlipidemia", "description": "A lipid metabolism disease that is characterized by elevated levels of lipids in the blood.", "url": "https://disease-ontology.org/term/DOID:1168", "evidence": [ { "id": "1168", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1168" } ], "weight": 0.0 }, { "disease_id": "DOID:1883", "name": "hepatitis C", "description": "A viral hepatitis that results_in inflammation located_in liver, has_material_basis_in hepatitis C virus (Hepacivirus hominis), which is transmitted_by blood from an infected person enters the body of an uninfected person. The infection has_symptom fever, has_symptom fatigue, has_symptom loss of appetite, has_symptom nausea, has_symptom vomiting, has_symptom abdominal pain, has_symptom clay-colored bowel movements, has_symptom joint pain, and has_symptom jaundice.", "url": "https://disease-ontology.org/term/DOID:1883", "evidence": [ { "id": "1883", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1883" } ], "weight": 0.0 }, { "disease_id": "DOID:2913", "name": "acute pancreatitis", "description": "A pancreatitis that is characterized by inflammation of the pancreas over a short period of time and has symptoms of severe abdominal pain, nausea, vomiting, diarrhea, fever, and shock.", "url": "https://disease-ontology.org/term/DOID:2913", "evidence": [ { "id": "2913", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2913" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQE9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQE9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQE9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQE9" } ], "pmid": "" }, { "name": "ISGF3 complex", "id": "GO:0070721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070721", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQE9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQE9" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQE9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQE9" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQE9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQE9" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQE9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQE9" } ], "pmid": "" }, { "name": "immune system process", "id": "GO:0002376", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002376", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQE9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQE9" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQE9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQE9" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQE9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQE9" } ], "pmid": "" }, { "name": "sequence-specific double-stranded DNA binding", "id": "GO:1990837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990837", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQE9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQE9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZQE9-1" }, { "uniprot_canonical_ac": "A0A8I5ZQF8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQF8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQF8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 86, "chemical_mass": 9806.0, "gene_names": "Fam236d", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZQF8-1" }, { "uniprot_canonical_ac": "A0A8I5ZQI7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQI7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQI7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 58, "chemical_mass": 7088.0, "gene_names": "ENSRNOG00000067646", "protein_name": "", "disease": [], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQI7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQI7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZQI7-1" }, { "uniprot_canonical_ac": "A0A8I5ZRW1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZRW1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZRW1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 67, "chemical_mass": 7641.0, "gene_names": "ENSRNOG00000069069", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZRW1-1" }, { "uniprot_canonical_ac": "A0A8I6A182-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A182", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A182" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 332, "chemical_mass": 38323.0, "gene_names": "Pitpnc1;Pitpnc1", "protein_name": "Cytoplasmic phosphatidylinositol transfer protein 1", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A182", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A182" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A182", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A182" } ], "pmid": "" } ], "molecular_function": [ { "name": "phospholipid transporter activity", "id": "GO:0005548", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005548", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A182", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A182" } ], "pmid": "" }, { "name": "phosphatidylinositol binding", "id": "GO:0035091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035091", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A182", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A182" } ], "pmid": "" }, { "name": "phosphatidic acid transfer activity", "id": "GO:1990050", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990050", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A182", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A182" } ], "pmid": "" }, { "name": "phosphatidylglycerol binding", "id": "GO:1901611", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901611", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A182", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A182" } ], "pmid": "" }, { "name": "phosphatidic acid binding", "id": "GO:0070300", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070300", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A182", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A182" } ], "pmid": "" }, { "name": "phosphatidylinositol transfer activity", "id": "GO:0008526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008526", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A182", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A182" } ], "pmid": "" } ], "biological_process": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A182", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A182" } ], "pmid": "" }, { "name": "phospholipid transport", "id": "GO:0015914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015914", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A182", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A182" } ], "pmid": "" }, { "name": "1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process", "id": "GO:1902635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902635", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A182", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A182" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6A182-1" }, { "uniprot_canonical_ac": "A0A8I5ZT42-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZT42", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZT42" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 177, "chemical_mass": 20562.0, "gene_names": "Lcnl;LOC681186;Lcnl", "protein_name": "", "disease": [], "molecular_function": [ { "name": "small molecule binding", "id": "GO:0036094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036094", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZT42", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZT42" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZT42-1" }, { "uniprot_canonical_ac": "A0A8I5ZT99-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZT99", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZT99" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 595, "chemical_mass": 68620.0, "gene_names": "Frmd3;Frmd3", "protein_name": "FERM domain-containing protein 3", "disease": [ { "disease_id": "DOID:0060081", "name": "triple-receptor negative breast cancer", "description": "A breast cancer that is characterized by the absence of estrogen, progresterone and Her2 receptors.", "url": "https://disease-ontology.org/term/DOID:0060081", "evidence": [ { "id": "0060081", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060081" } ], "weight": 0.0 }, { "disease_id": "DOID:0081275", "name": "neurodevelopmental disorder with eye movement abnormalities and ataxia", "description": "An autosomal dominant intellectual developmental disorder that is characterized by global developmental delay apparent from infancy and that has_material_basis_in heterozygous mutation in the FRMD5 gene on chromosome 15q15. Affected individuals show delayed walking with an unsteady gait, variably impaired intellectual development, learning disabilities, and speech difficulties.", "url": "https://disease-ontology.org/term/DOID:0081275", "evidence": [ { "id": "0081275", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081275" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZT99", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZT99" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZT99", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZT99" } ], "pmid": "" } ], "biological_process": [ { "name": "actomyosin structure organization", "id": "GO:0031032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031032", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZT99", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZT99" } ], "pmid": "" } ], "molecular_function": [ { "name": "cytoskeletal protein binding", "id": "GO:0008092", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008092", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZT99", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZT99" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZT99-1" }, { "uniprot_canonical_ac": "A0A8I5ZTC7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTC7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTC7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 671, "chemical_mass": 76149.0, "gene_names": "Zfp180", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTC7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTC7" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTC7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTC7" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTC7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTC7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZTC7-1" }, { "uniprot_canonical_ac": "A0A8I5ZU96-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZU96", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZU96" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 195, "chemical_mass": 21939.0, "gene_names": "ENSRNOG00000063798", "protein_name": "ADP-ribosylation factor 1", "disease": [], "molecular_function": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZU96", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZU96" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZU96", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZU96" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZU96", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZU96" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZU96-1" }, { "uniprot_canonical_ac": "A0A8I5ZUB0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUB0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUB0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 76, "chemical_mass": 8911.0, "gene_names": "ENSRNOG00000065001", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZUB0-1" }, { "uniprot_canonical_ac": "A0A8I5ZUN1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUN1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUN1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 216, "chemical_mass": 22994.0, "gene_names": "Blvrb", "protein_name": "Flavin reductase (NADPH)", "disease": [], "biological_process": [ { "name": "megakaryocyte differentiation", "id": "GO:0030219", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030219", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUN1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUN1" } ], "pmid": "" }, { "name": "cell fate specification", "id": "GO:0001708", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001708", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUN1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUN1" } ], "pmid": "" }, { "name": "negative regulation of insulin receptor signaling pathway", "id": "GO:0046627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046627", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUN1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUN1" } ], "pmid": "" }, { "name": "reactive oxygen species biosynthetic process", "id": "GO:1903409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903409", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUN1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUN1" } ], "pmid": "" }, { "name": "erythrocyte differentiation", "id": "GO:0030218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030218", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUN1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUN1" } ], "pmid": "" }, { "name": "animal organ morphogenesis", "id": "GO:0009887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009887", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUN1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUN1" } ], "pmid": "" }, { "name": "hemopoiesis", "id": "GO:0030097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030097", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUN1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUN1" } ], "pmid": "" }, { "name": "heme catabolic process", "id": "GO:0042167", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042167", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUN1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUN1" } ], "pmid": "" }, { "name": "cellular response to stress", "id": "GO:0033554", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033554", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUN1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUN1" } ], "pmid": "" }, { "name": "membrane lipid catabolic process", "id": "GO:0046466", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046466", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUN1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUN1" } ], "pmid": "" }, { "name": "bone marrow development", "id": "GO:0048539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048539", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUN1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUN1" } ], "pmid": "" }, { "name": "homeostasis of number of cells", "id": "GO:0048872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048872", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUN1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUN1" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUN1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUN1" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUN1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUN1" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUN1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUN1" } ], "pmid": "" }, { "name": "terminal bouton", "id": "GO:0043195", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043195", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUN1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUN1" } ], "pmid": "" } ], "molecular_function": [ { "name": "peptidyl-cysteine S-nitrosylase activity", "id": "GO:0035605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035605", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUN1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUN1" } ], "pmid": "" }, { "name": "biliverdin reductase [NAD(P)H] activity", "id": "GO:0004074", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004074", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUN1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUN1" } ], "pmid": "" }, { "name": "riboflavin reductase (NADPH) activity", "id": "GO:0042602", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042602", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUN1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUN1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZUN1-1" }, { "uniprot_canonical_ac": "A0A8I5ZWT7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZWT7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZWT7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 409, "chemical_mass": 45093.0, "gene_names": "ENSRNOG00000070329", "protein_name": "Perilipin", "disease": [], "cellular_component": [ { "name": "lipid droplet", "id": "GO:0005811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005811", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZWT7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZWT7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZWT7-1" }, { "uniprot_canonical_ac": "A0A8I5ZY38-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZY38", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZY38" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 475, "chemical_mass": 52448.0, "gene_names": "Gpbp1l2;AABR07045373.1;Gpbp1l2", "protein_name": "", "disease": [], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZY38", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZY38" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZY38", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZY38" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZY38", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZY38" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZY38", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZY38" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZY38", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZY38" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZY38", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZY38" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZY38", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZY38" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZY38-1" }, { "uniprot_canonical_ac": "A0A8I5ZZG4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZZG4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZZG4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 420, "chemical_mass": 45779.0, "gene_names": "Hnrnpk-ps1", "protein_name": "Heterogeneous nuclear ribonucleoprotein K", "disease": [ { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:10300", "name": "Raynaud disease", "description": "A peripheral vascular disease that is characterized by bilateral Raynaud phenomenon, the abrupt onset of digital paleness or cyanosis in response to cold exposure or stress.", "url": "https://disease-ontology.org/term/DOID:10300", "evidence": [ { "id": "10300", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10300" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZZG4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZZG4" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZZG4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZZG4" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZZG4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZZG4" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZZG4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZZG4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZZG4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZZG4" } ], "pmid": "" }, { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZZG4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZZG4" } ], "pmid": "" }, { "name": "podosome", "id": "GO:0002102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002102", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZZG4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZZG4" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZZG4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZZG4" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZZG4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZZG4" } ], "pmid": "" }, { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZZG4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZZG4" } ], "pmid": "" }, { "name": "negative regulation of gene expression", "id": "GO:0010629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010629", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZZG4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZZG4" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZZG4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZZG4" } ], "pmid": "" }, { "name": "regulation of apoptotic process", "id": "GO:0042981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042981", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZZG4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZZG4" } ], "pmid": "" }, { "name": "regulation of mRNA splicing, via spliceosome", "id": "GO:0048024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048024", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZZG4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZZG4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZZG4-1" }, { "uniprot_canonical_ac": "A0A8I6A072-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A072", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A072" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 237, "chemical_mass": 26427.0, "gene_names": "Rabl3", "protein_name": "Rab-like protein 3", "disease": [ { "disease_id": "DOID:1793", "name": "pancreatic cancer", "description": "An endocrine gland cancer located_in the pancreas.", "url": "https://disease-ontology.org/term/DOID:1793", "evidence": [ { "id": "1793", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1793" } ], "weight": 0.0 } ], "biological_process": [ { "name": "natural killer cell differentiation", "id": "GO:0001779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001779", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A072", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A072" } ], "pmid": "" }, { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A072", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A072" } ], "pmid": "" }, { "name": "protein stabilization", "id": "GO:0050821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050821", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A072", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A072" } ], "pmid": "" }, { "name": "B cell differentiation", "id": "GO:0030183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030183", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A072", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A072" } ], "pmid": "" }, { "name": "T cell differentiation in thymus", "id": "GO:0033077", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033077", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A072", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A072" } ], "pmid": "" }, { "name": "regulation of Ras protein signal transduction", "id": "GO:0046578", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046578", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A072", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A072" } ], "pmid": "" }, { "name": "positive regulation of cilium assembly", "id": "GO:0045724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045724", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A072", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A072" } ], "pmid": "" }, { "name": "regulation of protein lipidation", "id": "GO:1903059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903059", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A072", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A072" } ], "pmid": "" } ], "molecular_function": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A072", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A072" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A072", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A072" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A072", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A072" } ], "pmid": "" }, { "name": "G protein activity", "id": "GO:0003925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003925", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A072", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A072" } ], "pmid": "" } ], "cellular_component": [ { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A072", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A072" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6A072-1" }, { "uniprot_canonical_ac": "A0A8I6A079-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A079", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A079" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 317, "chemical_mass": 35721.0, "gene_names": "ENSRNOG00000067486", "protein_name": "Pseudouridine synthase II N-terminal domain-containing protein", "disease": [], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A079", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A079" } ], "pmid": "" }, { "name": "pseudouridine synthase activity", "id": "GO:0009982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009982", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A079", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A079" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A079", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A079" } ], "pmid": "" } ], "biological_process": [ { "name": "RNA processing", "id": "GO:0006396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006396", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A079", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A079" } ], "pmid": "" }, { "name": "mRNA pseudouridine synthesis", "id": "GO:1990481", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990481", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A079", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A079" } ], "pmid": "" }, { "name": "positive regulation of mitochondrial translation", "id": "GO:0070131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070131", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A079", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A079" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6A079-1" }, { "uniprot_canonical_ac": "A0A8I6A1G6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1G6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1G6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 372, "chemical_mass": 40558.0, "gene_names": "Rfxank", "protein_name": "", "disease": [ { "disease_id": "DOID:627", "name": "severe combined immunodeficiency", "description": "A combined T cell and B cell immunodeficiency that is caused by a defect in infection-fighting immune cells resulting in individuals with non-functional immune systems.", "url": "https://disease-ontology.org/term/DOID:627", "evidence": [ { "id": "627", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:627" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1G6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1G6" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1G6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1G6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1G6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1G6" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulator complex", "id": "GO:0090575", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090575", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1G6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1G6" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1G6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1G6" } ], "pmid": "" }, { "name": "Ras protein signal transduction", "id": "GO:0007265", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007265", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1G6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1G6" } ], "pmid": "" } ], "molecular_function": [ { "name": "histone deacetylase binding", "id": "GO:0042826", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042826", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1G6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1G6" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1G6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1G6" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1G6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1G6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6A1G6-1" }, { "uniprot_canonical_ac": "A0A8I6A3R0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A3R0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A3R0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 375, "chemical_mass": 42747.0, "gene_names": "Ccnb2-ps2", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A3R0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A3R0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A3R0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A3R0" } ], "pmid": "" }, { "name": "microtubule organizing center", "id": "GO:0005815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005815", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A3R0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A3R0" } ], "pmid": "" }, { "name": "cyclin-dependent protein kinase holoenzyme complex", "id": "GO:0000307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000307", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A3R0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A3R0" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A3R0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A3R0" } ], "pmid": "" }, { "name": "cyclin-dependent protein serine/threonine kinase regulator activity", "id": "GO:0016538", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016538", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A3R0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A3R0" } ], "pmid": "" } ], "biological_process": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A3R0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A3R0" } ], "pmid": "" }, { "name": "G1/S transition of mitotic cell cycle", "id": "GO:0000082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000082", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A3R0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A3R0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6A3R0-1" }, { "uniprot_canonical_ac": "A0A8I6A4Z0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A4Z0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A4Z0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 123, "chemical_mass": 13722.0, "gene_names": "Trav19;ENSRNOG00000065769", "protein_name": "", "disease": [], "cellular_component": [ { "name": "T cell receptor complex", "id": "GO:0042101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042101", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A4Z0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A4Z0" } ], "pmid": "" } ], "molecular_function": [ { "name": "peptide antigen binding", "id": "GO:0042605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042605", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A4Z0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A4Z0" } ], "pmid": "" } ], "biological_process": [ { "name": "adaptive immune response", "id": "GO:0002250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002250", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A4Z0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A4Z0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6A4Z0-1" }, { "uniprot_canonical_ac": "A0A8I6A6T1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A6T1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A6T1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 159, "chemical_mass": 17319.0, "gene_names": "LOC120099250;LOC120099250;SNRPC", "protein_name": "U1 small nuclear ribonucleoprotein C", "disease": [], "molecular_function": [ { "name": "pre-mRNA 5'-splice site binding", "id": "GO:0030627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030627", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A6T1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A6T1" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A6T1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A6T1" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A6T1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A6T1" } ], "pmid": "" }, { "name": "U1 snRNA binding", "id": "GO:0030619", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030619", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A6T1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A6T1" } ], "pmid": "" } ], "cellular_component": [ { "name": "U1 snRNP", "id": "GO:0005685", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005685", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A6T1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A6T1" } ], "pmid": "" }, { "name": "commitment complex", "id": "GO:0000243", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000243", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A6T1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A6T1" } ], "pmid": "" }, { "name": "U2-type prespliceosome", "id": "GO:0071004", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071004", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A6T1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A6T1" } ], "pmid": "" } ], "biological_process": [ { "name": "spliceosomal snRNP assembly", "id": "GO:0000387", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000387", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A6T1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A6T1" } ], "pmid": "" }, { "name": "mRNA 5'-splice site recognition", "id": "GO:0000395", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000395", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A6T1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A6T1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6A6T1-1" }, { "uniprot_canonical_ac": "A0A8I6A770-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A770", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A770" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 144, "chemical_mass": 16372.0, "gene_names": "ENSRNOG00000066038", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A770", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A770" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A770", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A770" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A770", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A770" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A770", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A770" } ], "pmid": "" } ], "biological_process": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A770", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A770" } ], "pmid": "" }, { "name": "sensory perception of smell", "id": "GO:0007608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007608", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A770", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A770" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6A770-1" }, { "uniprot_canonical_ac": "A0A8I6A7G6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A7G6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A7G6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 175, "chemical_mass": 19519.0, "gene_names": "Dnajc19", "protein_name": "Mitochondrial import inner membrane translocase subunit TIM14", "disease": [ { "disease_id": "DOID:0110000", "name": "3-methylglutaconic aciduria type 5", "description": "A 3-methylglutaconic aciduria that has_material_basis_in homozygous mutation in the DNAJC19 gene on chromosome 3q26.", "url": "https://disease-ontology.org/term/DOID:0110000", "evidence": [ { "id": "0110000", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110000" } ], "weight": 0.0 } ], "biological_process": [ { "name": "genitalia development", "id": "GO:0048806", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048806", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A7G6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A7G6" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A7G6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A7G6" } ], "pmid": "" }, { "name": "visual perception", "id": "GO:0007601", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007601", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A7G6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A7G6" } ], "pmid": "" }, { "name": "regulation of cardiolipin metabolic process", "id": "GO:1900208", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900208", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A7G6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A7G6" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A7G6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A7G6" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A7G6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A7G6" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A7G6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A7G6" } ], "pmid": "" }, { "name": "matrix side of mitochondrial inner membrane", "id": "GO:0099617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099617", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A7G6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A7G6" } ], "pmid": "" }, { "name": "inner mitochondrial membrane protein complex", "id": "GO:0098800", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098800", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A7G6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A7G6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6A7G6-1" }, { "uniprot_canonical_ac": "A0A8I6A878-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A878", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A878" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 404, "chemical_mass": 46768.0, "gene_names": "ENSRNOG00000063631", "protein_name": "Histone-lysine N-methyltransferase", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A878", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A878" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A878", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A878" } ], "pmid": "" }, { "name": "chromosome, centromeric region", "id": "GO:0000775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000775", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A878", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A878" } ], "pmid": "" }, { "name": "chromatin silencing complex", "id": "GO:0005677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005677", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A878", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A878" } ], "pmid": "" }, { "name": "nuclear lamina", "id": "GO:0005652", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005652", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A878", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A878" } ], "pmid": "" }, { "name": "heterochromatin", "id": "GO:0000792", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000792", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A878", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A878" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A878", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A878" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A878", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A878" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A878", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A878" } ], "pmid": "" }, { "name": "rhythmic process", "id": "GO:0048511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048511", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A878", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A878" } ], "pmid": "" }, { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A878", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A878" } ], "pmid": "" }, { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A878", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A878" } ], "pmid": "" }, { "name": "heterochromatin formation", "id": "GO:0031507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031507", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A878", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A878" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A878", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A878" } ], "pmid": "" }, { "name": "histone H3K9 methyltransferase activity", "id": "GO:0046974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046974", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A878", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A878" } ], "pmid": "" }, { "name": "histone H3K9me2 methyltransferase activity", "id": "GO:0140947", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140947", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A878", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A878" } ], "pmid": "" }, { "name": "histone H3K9 trimethyltransferase activity", "id": "GO:0140949", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140949", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A878", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A878" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6A878-1" }, { "uniprot_canonical_ac": "A0A8I6A9N9-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A9N9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A9N9" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 340, "chemical_mass": 37187.0, "gene_names": "C2cd4b;C2cd4b", "protein_name": "", "disease": [], "biological_process": [ { "name": "regulation of cell adhesion", "id": "GO:0030155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030155", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A9N9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A9N9" } ], "pmid": "" }, { "name": "positive regulation of acute inflammatory response", "id": "GO:0002675", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002675", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A9N9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A9N9" } ], "pmid": "" }, { "name": "regulation of vascular permeability involved in acute inflammatory response", "id": "GO:0002528", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002528", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A9N9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A9N9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6A9N9-1", "start_pos": "210", "end_pos": "210", "site_lbl": "Thr210", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 210, "start_aa": "Thr", "end_pos": 210, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr210", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6A9N9-1" }, { "uniprot_canonical_ac": "A0A8I6AA79-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AA79", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AA79" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 116, "chemical_mass": 13100.0, "gene_names": "ENSRNOG00000070857", "protein_name": "EF-hand domain-containing protein", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AA79", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AA79" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of cell population proliferation", "id": "GO:0042127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042127", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AA79", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AA79" } ], "pmid": "" } ], "molecular_function": [ { "name": "calcium-dependent protein binding", "id": "GO:0048306", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048306", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AA79", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AA79" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AA79", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AA79" } ], "pmid": "" }, { "name": "S100 protein binding", "id": "GO:0044548", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044548", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AA79", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AA79" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AA79-1" }, { "uniprot_canonical_ac": "A0A8I6AB22-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AB22", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AB22" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 97, "chemical_mass": 10542.0, "gene_names": "ENSRNOG00000067079", "protein_name": "Ig-like domain-containing protein", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AB22", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AB22" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AB22", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AB22" } ], "pmid": "" }, { "name": "immunoglobulin complex", "id": "GO:0019814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019814", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AB22", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AB22" } ], "pmid": "" } ], "biological_process": [ { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AB22", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AB22" } ], "pmid": "" }, { "name": "adaptive immune response", "id": "GO:0002250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002250", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AB22", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AB22" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6AB22-1", "start_pos": "14", "end_pos": "14", "site_lbl": "Thr14", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 14, "start_aa": "Thr", "end_pos": 14, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr14", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6AB22-1" }, { "uniprot_canonical_ac": "A0A8I6ACU5-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACU5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACU5" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 462, "chemical_mass": 50223.0, "gene_names": "Krt28;Ka41;Krt25d;Krt28", "protein_name": "", "disease": [], "cellular_component": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACU5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACU5" } ], "pmid": "" }, { "name": "keratin filament", "id": "GO:0045095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045095", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACU5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACU5" } ], "pmid": "" } ], "biological_process": [ { "name": "epithelial cell differentiation", "id": "GO:0030855", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030855", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACU5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACU5" } ], "pmid": "" }, { "name": "intermediate filament organization", "id": "GO:0045109", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045109", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACU5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACU5" } ], "pmid": "" }, { "name": "hair follicle morphogenesis", "id": "GO:0031069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031069", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACU5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACU5" } ], "pmid": "" }, { "name": "morphogenesis of an epithelium", "id": "GO:0002009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002009", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACU5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACU5" } ], "pmid": "" } ], "molecular_function": [ { "name": "structural constituent of skin epidermis", "id": "GO:0030280", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030280", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACU5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACU5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6ACU5-1" }, { "uniprot_canonical_ac": "A0A8I6ACY1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACY1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACY1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 138, "chemical_mass": 15682.0, "gene_names": "ENSRNOG00000067643", "protein_name": "Ig-like domain-containing protein", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACY1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACY1" } ], "pmid": "" }, { "name": "immunoglobulin complex", "id": "GO:0019814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019814", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACY1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACY1" } ], "pmid": "" } ], "molecular_function": [ { "name": "antigen binding", "id": "GO:0003823", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003823", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACY1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACY1" } ], "pmid": "" } ], "biological_process": [ { "name": "immunoglobulin mediated immune response", "id": "GO:0016064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016064", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACY1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACY1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6ACY1-1" }, { "uniprot_canonical_ac": "A0A8I6ADJ2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ADJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ADJ2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 259, "chemical_mass": 30569.0, "gene_names": "Dlgap5l1;Dlg5l7;Dlgap5l1;LOC103692302", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6ADJ2-1", "start_pos": "18", "end_pos": "18", "site_lbl": "Thr18", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 18, "start_aa": "Thr", "end_pos": 18, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr18", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6ADJ2-1" }, { "uniprot_canonical_ac": "A0A8I6AGU8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AGU8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AGU8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 374, "chemical_mass": 41967.0, "gene_names": "C3h9orf50;C3h9orf50;RGD1311084", "protein_name": "", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AGU8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AGU8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AGU8-1" }, { "uniprot_canonical_ac": "A0A8I6GGY4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GGY4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GGY4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 231, "chemical_mass": 26320.0, "gene_names": "Inca1;Inca1;RGD1306656", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GGY4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GGY4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GGY4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GGY4" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of cell population proliferation", "id": "GO:0008285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008285", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GGY4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GGY4" } ], "pmid": "" }, { "name": "positive regulation of apoptotic signaling pathway", "id": "GO:2001235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001235", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GGY4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GGY4" } ], "pmid": "" }, { "name": "negative regulation of cyclin-dependent protein serine/threonine kinase activity", "id": "GO:0045736", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045736", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GGY4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GGY4" } ], "pmid": "" } ], "molecular_function": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GGY4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GGY4" } ], "pmid": "" }, { "name": "protein-containing complex binding", "id": "GO:0044877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044877", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GGY4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GGY4" } ], "pmid": "" }, { "name": "cyclin-dependent protein serine/threonine kinase inhibitor activity", "id": "GO:0004861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004861", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GGY4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GGY4" } ], "pmid": "" }, { "name": "cyclin binding", "id": "GO:0030332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030332", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GGY4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GGY4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6GGY4-1", "start_pos": "143", "end_pos": "143", "site_lbl": "Thr143", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 143, "start_aa": "Thr", "end_pos": 143, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr143", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I6GGY4-1", "start_pos": "180", "end_pos": "180", "site_lbl": "Thr180", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 180, "start_aa": "Thr", "end_pos": 180, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr180", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6GGY4-1" }, { "uniprot_canonical_ac": "A0A8I6GLJ5-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GLJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GLJ5" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 327, "chemical_mass": 37217.0, "gene_names": "Or6d12;Olr824;Or6d12", "protein_name": "", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GLJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GLJ5" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GLJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GLJ5" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GLJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GLJ5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6GLJ5-1" }, { "uniprot_canonical_ac": "F7ESI5-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F7ESI5", "url": "https://www.uniprot.org/uniprotkb/F7ESI5" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 292, "chemical_mass": 32704.0, "gene_names": "Cfhr1", "protein_name": "", "disease": [ { "disease_id": "DOID:0080301", "name": "atypical hemolytic-uremic syndrome", "description": "A complement deficiency that is characterized by mechanical hemolytic anemia, thrombocytopenia, and renal dysfunction.", "url": "https://disease-ontology.org/term/DOID:0080301", "evidence": [ { "id": "0080301", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080301" } ], "weight": 0.0 }, { "disease_id": "DOID:0110014", "name": "age related macular degeneration 1", "description": "An age related macular degeneration associated with polymorphism in the hemicentin gene (HMCN1) on chromosome 1q25.3-q31.1.", "url": "https://disease-ontology.org/term/DOID:0110014", "evidence": [ { "id": "0110014", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110014" } ], "weight": 0.0 }, { "disease_id": "DOID:9119", "name": "acute myeloid leukemia", "description": "A myeloid leukemia that is characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal blood cells.", "url": "https://disease-ontology.org/term/DOID:9119", "evidence": [ { "id": "9119", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9119" } ], "weight": 0.0 }, { "disease_id": "DOID:9538", "name": "multiple myeloma", "description": "A myeloid neoplasm that is located_in the plasma cells in bone marrow.", "url": "https://disease-ontology.org/term/DOID:9538", "evidence": [ { "id": "9538", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9538" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "F7ESI5", "url": "https://www.uniprot.org/uniprotkb/F7ESI5" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "F7ESI5", "url": "https://www.uniprot.org/uniprotkb/F7ESI5" } ], "pmid": "" } ], "molecular_function": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "F7ESI5", "url": "https://www.uniprot.org/uniprotkb/F7ESI5" } ], "pmid": "" }, { "name": "complement component C3b binding", "id": "GO:0001851", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001851", "evidence": [ { "database": "UniProtKB", "id": "F7ESI5", "url": "https://www.uniprot.org/uniprotkb/F7ESI5" } ], "pmid": "" } ], "biological_process": [ { "name": "blood coagulation", "id": "GO:0007596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007596", "evidence": [ { "database": "UniProtKB", "id": "F7ESI5", "url": "https://www.uniprot.org/uniprotkb/F7ESI5" } ], "pmid": "" }, { "name": "cytolysis by host of symbiont cells", "id": "GO:0051838", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051838", "evidence": [ { "database": "UniProtKB", "id": "F7ESI5", "url": "https://www.uniprot.org/uniprotkb/F7ESI5" } ], "pmid": "" }, { "name": "complement activation", "id": "GO:0006956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006956", "evidence": [ { "database": "UniProtKB", "id": "F7ESI5", "url": "https://www.uniprot.org/uniprotkb/F7ESI5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F7ESI5-1" }, { "uniprot_canonical_ac": "A0A8I6GI80-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI80", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI80" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 492, "chemical_mass": 53478.0, "gene_names": "Meis1", "protein_name": "", "disease": [ { "disease_id": "DOID:0050425", "name": "restless legs syndrome", "description": "A central nervous system disease characterized by throbbing, pulling creeping or other unpleasant sensations in the legs and the irresistible urge to move them.", "url": "https://disease-ontology.org/term/DOID:0050425", "evidence": [ { "id": "0050425", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050425" } ], "weight": 0.0 }, { "disease_id": "DOID:114", "name": "heart disease", "description": "A cardiovascular system disease that involves the heart.", "url": "https://disease-ontology.org/term/DOID:114", "evidence": [ { "id": "114", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:114" } ], "weight": 0.0 }, { "disease_id": "DOID:1240", "name": "leukemia", "description": "A cancer that affects the blood or bone marrow characterized by an abnormal proliferation of blood cells.", "url": "https://disease-ontology.org/term/DOID:1240", "evidence": [ { "id": "1240", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1240" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI80", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI80" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI80", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI80" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI80", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI80" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI80", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI80" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI80", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI80" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI80", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI80" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI80", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI80" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI80", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI80" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI80", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI80" } ], "pmid": "" } ], "biological_process": [ { "name": "angiogenesis", "id": "GO:0001525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001525", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI80", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI80" } ], "pmid": "" }, { "name": "locomotory behavior", "id": "GO:0007626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007626", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI80", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI80" } ], "pmid": "" }, { "name": "negative regulation of neuron differentiation", "id": "GO:0045665", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045665", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI80", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI80" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI80", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI80" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI80", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI80" } ], "pmid": "" }, { "name": "blood vessel morphogenesis", "id": "GO:0048514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048514", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI80", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI80" } ], "pmid": "" }, { "name": "cell growth involved in cardiac muscle cell development", "id": "GO:0061049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061049", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI80", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI80" } ], "pmid": "" }, { "name": "hemopoiesis", "id": "GO:0030097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030097", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI80", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI80" } ], "pmid": "" }, { "name": "megakaryocyte development", "id": "GO:0035855", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035855", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI80", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI80" } ], "pmid": "" }, { "name": "definitive hemopoiesis", "id": "GO:0060216", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060216", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI80", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI80" } ], "pmid": "" }, { "name": "negative regulation of myeloid cell differentiation", "id": "GO:0045638", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045638", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI80", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI80" } ], "pmid": "" }, { "name": "lens morphogenesis in camera-type eye", "id": "GO:0002089", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002089", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI80", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI80" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6GI80-1", "start_pos": "228", "end_pos": "228", "site_lbl": "Thr228", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 228, "start_aa": "Thr", "end_pos": 228, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr228", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6GI80-1" }, { "uniprot_canonical_ac": "A0A8I6AJ59-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJ59", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJ59" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 317, "chemical_mass": 35449.0, "gene_names": "Olr1675;Or2n1j;Or2n1;LOC120098956;Olr1682;Or2n1g;Or2n1h;Or2n1i;Or2n1j;Or2n1k;Or2n1l;Or2n1n;Or2n1", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJ59", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJ59" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJ59", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJ59" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJ59", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJ59" } ], "pmid": "" } ], "biological_process": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJ59", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJ59" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AJ59-1" }, { "uniprot_canonical_ac": "F7F444-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F7F444", "url": "https://www.uniprot.org/uniprotkb/F7F444" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 212, "chemical_mass": 24170.0, "gene_names": "Cinp;Cinp;RGD1563395", "protein_name": "", "disease": [], "molecular_function": [ { "name": "preribosome binding", "id": "GO:1990275", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990275", "evidence": [ { "database": "UniProtKB", "id": "F7F444", "url": "https://www.uniprot.org/uniprotkb/F7F444" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F7F444", "url": "https://www.uniprot.org/uniprotkb/F7F444" } ], "pmid": "" }, { "name": "ATPase complex", "id": "GO:1904949", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904949", "evidence": [ { "database": "UniProtKB", "id": "F7F444", "url": "https://www.uniprot.org/uniprotkb/F7F444" } ], "pmid": "" } ], "biological_process": [ { "name": "ribosomal large subunit biogenesis", "id": "GO:0042273", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042273", "evidence": [ { "database": "UniProtKB", "id": "F7F444", "url": "https://www.uniprot.org/uniprotkb/F7F444" } ], "pmid": "" }, { "name": "DNA replication", "id": "GO:0006260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006260", "evidence": [ { "database": "UniProtKB", "id": "F7F444", "url": "https://www.uniprot.org/uniprotkb/F7F444" } ], "pmid": "" }, { "name": "regulation of ribosome biogenesis", "id": "GO:0090069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090069", "evidence": [ { "database": "UniProtKB", "id": "F7F444", "url": "https://www.uniprot.org/uniprotkb/F7F444" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F7F444-1" }, { "uniprot_canonical_ac": "A0A8I6A2N3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2N3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2N3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 4865, "chemical_mass": 532487.0, "gene_names": "Mycbp2", "protein_name": "E3 ubiquitin-protein ligase MYCBP2", "disease": [ { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:219", "name": "colon cancer", "description": "A colorectal cancer that is located_in the colon.", "url": "https://disease-ontology.org/term/DOID:219", "evidence": [ { "id": "219", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:219" } ], "weight": 0.0 }, { "disease_id": "DOID:3963", "name": "thyroid gland carcinoma", "description": "A thyroid gland cancer that has_material_basis_in epithelial cells.", "url": "https://disease-ontology.org/term/DOID:3963", "evidence": [ { "id": "3963", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3963" } ], "weight": 0.0 }, { "disease_id": "DOID:936", "name": "brain disease", "description": "A central nervous system disease that is located_in the brain.", "url": "https://disease-ontology.org/term/DOID:936", "evidence": [ { "id": "936", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:936" } ], "weight": 0.0 } ], "biological_process": [ { "name": "regulation of axon guidance", "id": "GO:1902667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902667", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2N3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2N3" } ], "pmid": "" }, { "name": "neuromuscular process", "id": "GO:0050905", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050905", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2N3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2N3" } ], "pmid": "" }, { "name": "regulation of protein localization", "id": "GO:0032880", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032880", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2N3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2N3" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2N3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2N3" } ], "pmid": "" }, { "name": "positive regulation of protein ubiquitination", "id": "GO:0031398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031398", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2N3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2N3" } ], "pmid": "" }, { "name": "central nervous system projection neuron axonogenesis", "id": "GO:0021952", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021952", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2N3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2N3" } ], "pmid": "" }, { "name": "negative regulation of protein catabolic process", "id": "GO:0042177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042177", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2N3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2N3" } ], "pmid": "" }, { "name": "protein K48-linked ubiquitination", "id": "GO:0070936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070936", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2N3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2N3" } ], "pmid": "" }, { "name": "circadian regulation of gene expression", "id": "GO:0032922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032922", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2N3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2N3" } ], "pmid": "" }, { "name": "regulation of cytoskeleton organization", "id": "GO:0051493", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051493", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2N3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2N3" } ], "pmid": "" }, { "name": "motor neuron axon guidance", "id": "GO:0008045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008045", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2N3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2N3" } ], "pmid": "" }, { "name": "cell morphogenesis involved in neuron differentiation", "id": "GO:0048667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048667", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2N3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2N3" } ], "pmid": "" }, { "name": "branchiomotor neuron axon guidance", "id": "GO:0021785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021785", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2N3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2N3" } ], "pmid": "" }, { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2N3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2N3" } ], "pmid": "" }, { "name": "regulation of synaptic assembly at neuromuscular junction", "id": "GO:0008582", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008582", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2N3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2N3" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2N3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2N3" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2N3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2N3" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2N3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2N3" } ], "pmid": "" }, { "name": "microtubule cytoskeleton", "id": "GO:0015630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015630", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2N3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2N3" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2N3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2N3" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2N3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2N3" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2N3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2N3" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2N3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2N3" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2N3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2N3" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2N3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2N3" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2N3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2N3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6A2N3-1", "start_pos": "1672", "end_pos": "1672", "site_lbl": "Thr1672", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1672, "start_aa": "Thr", "end_pos": 1672, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1672", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I6A2N3-1", "start_pos": "19", "end_pos": "19", "site_lbl": "Thr19", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 19, "start_aa": "Thr", "end_pos": 19, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr19", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I6A2N3-1", "start_pos": "4068", "end_pos": "4068", "site_lbl": "Thr4068", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "reported site T3995 is on non-canonical isoform A0A1W2Q679-1 which maps to canonical isoform site A0A8I6A2N3-1:4068", "icn3d_view": {}, "start_pos": 4068, "start_aa": "Thr", "end_pos": 4068, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr4068", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I6A2N3-1", "start_pos": "4111", "end_pos": "4111", "site_lbl": "Thr4111", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 4111, "start_aa": "Thr", "end_pos": 4111, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr4111", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6A2N3-1" }, { "uniprot_canonical_ac": "A0A8I6AE43-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AE43", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AE43" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1451, "chemical_mass": 162264.0, "gene_names": "Erbin;Erbb2ip;Erbb2i;Erbin;RGD1562952", "protein_name": "Erbin", "disease": [], "cellular_component": [ { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AE43", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AE43" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AE43", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AE43" } ], "pmid": "" }, { "name": "hemidesmosome", "id": "GO:0030056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030056", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AE43", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AE43" } ], "pmid": "" }, { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AE43", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AE43" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AE43", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AE43" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AE43", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AE43" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AE43", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AE43" } ], "pmid": "" }, { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AE43", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AE43" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AE43", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AE43" } ], "pmid": "" }, { "name": "cell junction", "id": "GO:0030054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030054", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AE43", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AE43" } ], "pmid": "" }, { "name": "neuromuscular junction", "id": "GO:0031594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031594", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AE43", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AE43" } ], "pmid": "" }, { "name": "postsynapse", "id": "GO:0098794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098794", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AE43", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AE43" } ], "pmid": "" }, { "name": "postsynaptic specialization", "id": "GO:0099572", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099572", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AE43", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AE43" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AE43", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AE43" } ], "pmid": "" }, { "name": "negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway", "id": "GO:0070433", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070433", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AE43", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AE43" } ], "pmid": "" }, { "name": "neurotransmitter receptor transport, endosome to postsynaptic membrane", "id": "GO:0098887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098887", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AE43", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AE43" } ], "pmid": "" }, { "name": "response to lipopolysaccharide", "id": "GO:0032496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032496", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AE43", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AE43" } ], "pmid": "" }, { "name": "protein targeting", "id": "GO:0006605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006605", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AE43", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AE43" } ], "pmid": "" }, { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AE43", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AE43" } ], "pmid": "" }, { "name": "negative regulation of monocyte chemotactic protein-1 production", "id": "GO:0071638", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071638", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AE43", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AE43" } ], "pmid": "" }, { "name": "receptor clustering", "id": "GO:0043113", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043113", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AE43", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AE43" } ], "pmid": "" }, { "name": "cellular response to tumor necrosis factor", "id": "GO:0071356", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071356", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AE43", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AE43" } ], "pmid": "" }, { "name": "response to muramyl dipeptide", "id": "GO:0032495", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032495", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AE43", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AE43" } ], "pmid": "" }, { "name": "establishment or maintenance of epithelial cell apical/basal polarity", "id": "GO:0045197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045197", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AE43", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AE43" } ], "pmid": "" }, { "name": "regulation of postsynaptic membrane neurotransmitter receptor levels", "id": "GO:0099072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099072", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AE43", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AE43" } ], "pmid": "" } ], "molecular_function": [ { "name": "signaling receptor binding", "id": "GO:0005102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005102", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AE43", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AE43" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AE43", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AE43" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AE43-1" }, { "uniprot_canonical_ac": "A0A8I6ATG9-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATG9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATG9" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1414, "chemical_mass": 150004.0, "gene_names": "Heg1;Heg1;RGD1564641", "protein_name": "", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATG9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATG9" } ], "pmid": "" }, { "name": "cell-cell junction", "id": "GO:0005911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005911", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATG9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATG9" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATG9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATG9" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATG9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATG9" } ], "pmid": "" } ], "molecular_function": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATG9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATG9" } ], "pmid": "" } ], "biological_process": [ { "name": "heart development", "id": "GO:0007507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007507", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATG9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATG9" } ], "pmid": "" }, { "name": "negative regulation of Rho-dependent protein serine/threonine kinase activity", "id": "GO:2000299", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000299", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATG9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATG9" } ], "pmid": "" }, { "name": "vasculogenesis", "id": "GO:0001570", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001570", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATG9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATG9" } ], "pmid": "" }, { "name": "in utero embryonic development", "id": "GO:0001701", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001701", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATG9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATG9" } ], "pmid": "" }, { "name": "lung development", "id": "GO:0030324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030324", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATG9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATG9" } ], "pmid": "" }, { "name": "multicellular organism growth", "id": "GO:0035264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035264", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATG9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATG9" } ], "pmid": "" }, { "name": "post-embryonic development", "id": "GO:0009791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009791", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATG9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATG9" } ], "pmid": "" }, { "name": "ventricular septum development", "id": "GO:0003281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003281", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATG9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATG9" } ], "pmid": "" }, { "name": "vasculature development", "id": "GO:0001944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001944", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATG9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATG9" } ], "pmid": "" }, { "name": "negative regulation of Rho protein signal transduction", "id": "GO:0035024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035024", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATG9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATG9" } ], "pmid": "" }, { "name": "endothelial cell morphogenesis", "id": "GO:0001886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATG9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATG9" } ], "pmid": "" }, { "name": "regulation of body fluid levels", "id": "GO:0050878", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050878", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATG9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATG9" } ], "pmid": "" }, { "name": "lymph vessel development", "id": "GO:0001945", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001945", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATG9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATG9" } ], "pmid": "" }, { "name": "ventricular trabecula myocardium morphogenesis", "id": "GO:0003222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003222", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATG9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATG9" } ], "pmid": "" }, { "name": "pericardium development", "id": "GO:0060039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060039", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATG9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATG9" } ], "pmid": "" }, { "name": "cardiac atrium morphogenesis", "id": "GO:0003209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003209", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATG9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATG9" } ], "pmid": "" }, { "name": "cardiac muscle tissue growth", "id": "GO:0055017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055017", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATG9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATG9" } ], "pmid": "" }, { "name": "positive regulation of fibroblast growth factor production", "id": "GO:0090271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090271", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATG9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATG9" } ], "pmid": "" }, { "name": "endothelial cell development", "id": "GO:0001885", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001885", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATG9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATG9" } ], "pmid": "" }, { "name": "cell-cell junction organization", "id": "GO:0045216", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045216", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATG9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATG9" } ], "pmid": "" }, { "name": "venous blood vessel morphogenesis", "id": "GO:0048845", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048845", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATG9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATG9" } ], "pmid": "" }, { "name": "lymph circulation", "id": "GO:0003017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003017", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATG9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATG9" } ], "pmid": "" }, { "name": "protein localization to cell junction", "id": "GO:1902414", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902414", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATG9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATG9" } ], "pmid": "" }, { "name": "negative regulation of membrane permeability", "id": "GO:1905709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905709", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATG9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATG9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6ATG9-1" }, { "uniprot_canonical_ac": "A0A8I6ACN8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACN8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACN8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 795, "chemical_mass": 88600.0, "gene_names": "Naaladl2;Naaladl2", "protein_name": "", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACN8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACN8" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACN8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACN8" } ], "pmid": "" } ], "biological_process": [ { "name": "response to bacterium", "id": "GO:0009617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009617", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACN8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACN8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6ACN8-1", "start_pos": "357", "end_pos": "357", "site_lbl": "Thr357", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 357, "start_aa": "Thr", "end_pos": 357, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr357", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6ACN8-1" }, { "uniprot_canonical_ac": "A0A0G2JYZ3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JYZ3", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JYZ3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 251, "chemical_mass": 27814.0, "gene_names": "Fam3a", "protein_name": "", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JYZ3", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JYZ3" } ], "pmid": "" } ], "molecular_function": [ { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JYZ3", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JYZ3" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of antifungal innate immune response", "id": "GO:1905035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905035", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JYZ3", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JYZ3" } ], "pmid": "" }, { "name": "antifungal humoral response", "id": "GO:0019732", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019732", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JYZ3", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JYZ3" } ], "pmid": "" }, { "name": "antimicrobial humoral immune response mediated by antimicrobial peptide", "id": "GO:0061844", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061844", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JYZ3", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JYZ3" } ], "pmid": "" }, { "name": "ATP biosynthetic process", "id": "GO:0006754", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006754", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JYZ3", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JYZ3" } ], "pmid": "" }, { "name": "glucose metabolic process", "id": "GO:0006006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006006", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JYZ3", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JYZ3" } ], "pmid": "" }, { "name": "response to glucose", "id": "GO:0009749", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009749", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JYZ3", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JYZ3" } ], "pmid": "" }, { "name": "mitochondrion organization", "id": "GO:0007005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007005", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JYZ3", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JYZ3" } ], "pmid": "" }, { "name": "calcium ion homeostasis", "id": "GO:0055074", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055074", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JYZ3", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JYZ3" } ], "pmid": "" }, { "name": "insulin secretion", "id": "GO:0030073", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030073", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JYZ3", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JYZ3" } ], "pmid": "" }, { "name": "gene expression", "id": "GO:0010467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010467", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JYZ3", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JYZ3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A0G2JYZ3-1" }, { "uniprot_canonical_ac": "A0A0G2KB09-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KB09", "url": "https://www.uniprot.org/uniprotkb/A0A0G2KB09" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 365, "chemical_mass": 41701.0, "gene_names": "Parvb;Parvb", "protein_name": "", "disease": [ { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KB09", "url": "https://www.uniprot.org/uniprotkb/A0A0G2KB09" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KB09", "url": "https://www.uniprot.org/uniprotkb/A0A0G2KB09" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KB09", "url": "https://www.uniprot.org/uniprotkb/A0A0G2KB09" } ], "pmid": "" }, { "name": "focal adhesion", "id": "GO:0005925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005925", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KB09", "url": "https://www.uniprot.org/uniprotkb/A0A0G2KB09" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KB09", "url": "https://www.uniprot.org/uniprotkb/A0A0G2KB09" } ], "pmid": "" }, { "name": "lamellipodium", "id": "GO:0030027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030027", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KB09", "url": "https://www.uniprot.org/uniprotkb/A0A0G2KB09" } ], "pmid": "" }, { "name": "Z disc", "id": "GO:0030018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030018", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KB09", "url": "https://www.uniprot.org/uniprotkb/A0A0G2KB09" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KB09", "url": "https://www.uniprot.org/uniprotkb/A0A0G2KB09" } ], "pmid": "" } ], "biological_process": [ { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KB09", "url": "https://www.uniprot.org/uniprotkb/A0A0G2KB09" } ], "pmid": "" }, { "name": "lamellipodium assembly", "id": "GO:0030032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030032", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KB09", "url": "https://www.uniprot.org/uniprotkb/A0A0G2KB09" } ], "pmid": "" }, { "name": "substrate adhesion-dependent cell spreading", "id": "GO:0034446", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034446", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KB09", "url": "https://www.uniprot.org/uniprotkb/A0A0G2KB09" } ], "pmid": "" }, { "name": "establishment or maintenance of cell polarity regulating cell shape", "id": "GO:0071963", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071963", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KB09", "url": "https://www.uniprot.org/uniprotkb/A0A0G2KB09" } ], "pmid": "" }, { "name": "cell projection assembly", "id": "GO:0030031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030031", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KB09", "url": "https://www.uniprot.org/uniprotkb/A0A0G2KB09" } ], "pmid": "" }, { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KB09", "url": "https://www.uniprot.org/uniprotkb/A0A0G2KB09" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A0G2KB09-1" }, { "uniprot_canonical_ac": "A0A8I6AHX2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHX2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHX2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 2430, "chemical_mass": 267485.0, "gene_names": "Rif1", "protein_name": "Telomere-associated protein RIF1", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHX2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHX2" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHX2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHX2" } ], "pmid": "" }, { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHX2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHX2" } ], "pmid": "" }, { "name": "site of double-strand break", "id": "GO:0035861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035861", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHX2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHX2" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHX2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHX2" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHX2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHX2" } ], "pmid": "" }, { "name": "spindle midzone", "id": "GO:0051233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051233", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHX2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHX2" } ], "pmid": "" }, { "name": "condensed chromosome", "id": "GO:0000793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000793", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHX2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHX2" } ], "pmid": "" }, { "name": "female pronucleus", "id": "GO:0001939", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001939", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHX2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHX2" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHX2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHX2" } ], "pmid": "" }, { "name": "male pronucleus", "id": "GO:0001940", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001940", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHX2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHX2" } ], "pmid": "" }, { "name": "chromosome, telomeric repeat region", "id": "GO:0140445", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140445", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHX2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHX2" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of double-strand break repair via homologous recombination", "id": "GO:2000042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000042", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHX2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHX2" } ], "pmid": "" }, { "name": "positive regulation of double-strand break repair via nonhomologous end joining", "id": "GO:2001034", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001034", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHX2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHX2" } ], "pmid": "" }, { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHX2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHX2" } ], "pmid": "" }, { "name": "telomere maintenance", "id": "GO:0000723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000723", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHX2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHX2" } ], "pmid": "" }, { "name": "subtelomeric heterochromatin formation", "id": "GO:0031509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031509", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHX2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHX2" } ], "pmid": "" }, { "name": "telomere maintenance in response to DNA damage", "id": "GO:0043247", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043247", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHX2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHX2" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHX2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHX2" } ], "pmid": "" }, { "name": "cellular response to leukemia inhibitory factor", "id": "GO:1990830", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990830", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHX2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHX2" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHX2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHX2" } ], "pmid": "" }, { "name": "stem cell population maintenance", "id": "GO:0019827", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019827", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHX2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHX2" } ], "pmid": "" }, { "name": "negative regulation of gene expression, epigenetic", "id": "GO:0045814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045814", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHX2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHX2" } ], "pmid": "" }, { "name": "positive regulation of isotype switching", "id": "GO:0045830", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045830", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHX2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHX2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6AHX2-1", "start_pos": "392", "end_pos": "392", "site_lbl": "Thr392", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 392, "start_aa": "Thr", "end_pos": 392, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr392", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I6AHX2-1", "start_pos": "620", "end_pos": "620", "site_lbl": "Thr620", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 620, "start_aa": "Thr", "end_pos": 620, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr620", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I6AHX2-1", "start_pos": "977", "end_pos": "977", "site_lbl": "Asp977", "weight": 0.0, "snv": [ { "sequence_org": "D", "sequence_mut": "N", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (DES->NES).", "chr_id": "3", "chr_pos": "56997245", "evidence": [ { "id": "rs3319842542", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3319842542" } ] } ] } ], "record_id": "A0A8I6AHX2-1" }, { "uniprot_canonical_ac": "A0A8I5ZT67-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZT67", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZT67" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 744, "chemical_mass": 86259.0, "gene_names": "Zfp120l1;LOC102555317;Zfp120l1", "protein_name": "", "disease": [], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZT67", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZT67" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZT67", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZT67" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZT67", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZT67" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZT67", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZT67" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZT67", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZT67" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZT67", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZT67" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZT67", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZT67" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZT67-1" }, { "uniprot_canonical_ac": "A0A8I6AFP3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AFP3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AFP3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1129, "chemical_mass": 129301.0, "gene_names": "Atp11c;Atp11c-ps1;Atp11c;RGD1564481", "protein_name": "Phospholipid-transporting ATPase", "disease": [ { "disease_id": "DOID:0111846", "name": "X-linked congenital hemolytic anemia", "description": "A congenital hemolytic anemia characterized by mild congenital hemolytic anemia without morphologic red cell abnormalities that has_material_basis_in hemizygous mutation in the ATP11C gene on chromosome Xq27.1.", "url": "https://disease-ontology.org/term/DOID:0111846", "evidence": [ { "id": "0111846", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111846" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AFP3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AFP3" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AFP3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AFP3" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AFP3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AFP3" } ], "pmid": "" }, { "name": "phosphatidylethanolamine flippase activity", "id": "GO:0090555", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090555", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AFP3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AFP3" } ], "pmid": "" }, { "name": "ATPase-coupled intramembrane lipid transporter activity", "id": "GO:0140326", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140326", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AFP3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AFP3" } ], "pmid": "" }, { "name": "phosphatidylserine flippase activity", "id": "GO:0140346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140346", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AFP3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AFP3" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AFP3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AFP3" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AFP3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AFP3" } ], "pmid": "" }, { "name": "recycling endosome", "id": "GO:0055037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055037", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AFP3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AFP3" } ], "pmid": "" }, { "name": "phospholipid-translocating ATPase complex", "id": "GO:1990531", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990531", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AFP3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AFP3" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AFP3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AFP3" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AFP3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AFP3" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AFP3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AFP3" } ], "pmid": "" }, { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AFP3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AFP3" } ], "pmid": "" }, { "name": "recycling endosome membrane", "id": "GO:0055038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055038", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AFP3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AFP3" } ], "pmid": "" } ], "biological_process": [ { "name": "phospholipid translocation", "id": "GO:0045332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045332", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AFP3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AFP3" } ], "pmid": "" }, { "name": "pre-B cell differentiation", "id": "GO:0002329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002329", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AFP3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AFP3" } ], "pmid": "" }, { "name": "positive regulation of B cell differentiation", "id": "GO:0045579", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045579", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AFP3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AFP3" } ], "pmid": "" }, { "name": "phospholipid transport", "id": "GO:0015914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015914", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AFP3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AFP3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AFP3-1" }, { "uniprot_canonical_ac": "A0A8I6GMR5-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GMR5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GMR5" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 855, "chemical_mass": 101479.0, "gene_names": "Rbm25l1;Rbm25;Rbm25l1;Rbm25", "protein_name": "RNA-binding protein 25", "disease": [], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GMR5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GMR5" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GMR5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GMR5" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of alternative mRNA splicing, via spliceosome", "id": "GO:0000381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000381", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GMR5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GMR5" } ], "pmid": "" }, { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GMR5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GMR5" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GMR5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GMR5" } ], "pmid": "" }, { "name": "regulation of apoptotic process", "id": "GO:0042981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042981", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GMR5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GMR5" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GMR5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GMR5" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GMR5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GMR5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6GMR5-1" }, { "uniprot_canonical_ac": "A0A8I6A567-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A567", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A567" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 2439, "chemical_mass": 266986.0, "gene_names": "Cep192;Seh1l;Cep192;Da1-6;Seh1l", "protein_name": "", "disease": [], "biological_process": [ { "name": "positive regulation of TORC1 signaling", "id": "GO:1904263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904263", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A567", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A567" } ], "pmid": "" }, { "name": "attachment of mitotic spindle microtubules to kinetochore", "id": "GO:0051315", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051315", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A567", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A567" } ], "pmid": "" }, { "name": "nuclear pore organization", "id": "GO:0006999", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006999", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A567", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A567" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A567", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A567" } ], "pmid": "" }, { "name": "defense response to Gram-positive bacterium", "id": "GO:0050830", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050830", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A567", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A567" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A567", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A567" } ], "pmid": "" }, { "name": "cellular response to nutrient levels", "id": "GO:0031669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031669", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A567", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A567" } ], "pmid": "" }, { "name": "mitotic metaphase chromosome alignment", "id": "GO:0007080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007080", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A567", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A567" } ], "pmid": "" }, { "name": "cellular response to amino acid starvation", "id": "GO:0034198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034198", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A567", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A567" } ], "pmid": "" }, { "name": "protein-containing complex localization", "id": "GO:0031503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031503", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A567", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A567" } ], "pmid": "" }, { "name": "centrosome-templated microtubule nucleation", "id": "GO:0090222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090222", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A567", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A567" } ], "pmid": "" }, { "name": "centrosome duplication", "id": "GO:0051298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051298", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A567", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A567" } ], "pmid": "" }, { "name": "protein localization to centrosome", "id": "GO:0071539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071539", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A567", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A567" } ], "pmid": "" }, { "name": "mitotic spindle assembly", "id": "GO:0090307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090307", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A567", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A567" } ], "pmid": "" }, { "name": "response to bacterium", "id": "GO:0009617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009617", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A567", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A567" } ], "pmid": "" }, { "name": "centrosome cycle", "id": "GO:0007098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007098", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A567", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A567" } ], "pmid": "" } ], "cellular_component": [ { "name": "nuclear pore outer ring", "id": "GO:0031080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031080", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A567", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A567" } ], "pmid": "" }, { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A567", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A567" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A567", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A567" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A567", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A567" } ], "pmid": "" }, { "name": "GATOR2 complex", "id": "GO:0061700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061700", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A567", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A567" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A567", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A567" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A567", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A567" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A567", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A567" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A567", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A567" } ], "pmid": "" }, { "name": "pericentriolar material", "id": "GO:0000242", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000242", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A567", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A567" } ], "pmid": "" }, { "name": "procentriole replication complex", "id": "GO:0120099", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120099", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A567", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A567" } ], "pmid": "" }, { "name": "procentriole", "id": "GO:0120098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120098", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A567", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A567" } ], "pmid": "" } ], "molecular_function": [ { "name": "structural molecule activity", "id": "GO:0005198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005198", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A567", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A567" } ], "pmid": "" }, { "name": "phosphatase binding", "id": "GO:0019902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019902", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A567", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A567" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6A567-1", "start_pos": "984", "end_pos": "984", "site_lbl": "Thr984", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 984, "start_aa": "Thr", "end_pos": 984, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr984", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6A567-1" }, { "uniprot_canonical_ac": "A0A8I6AJW7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJW7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJW7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 316, "chemical_mass": 35317.0, "gene_names": "Or2ag19b;Olr214;Or2ag19", "protein_name": "", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJW7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJW7" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJW7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJW7" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJW7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJW7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6AJW7-1", "start_pos": "282", "end_pos": "282", "site_lbl": "Thr282", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 282, "start_aa": "Thr", "end_pos": 282, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr282", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6AJW7-1" }, { "uniprot_canonical_ac": "A0A8I5ZUI1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUI1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUI1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 557, "chemical_mass": 62213.0, "gene_names": "Ralgps1", "protein_name": "Ras-specific guanine nucleotide-releasing factor RalGPS1", "disease": [], "biological_process": [ { "name": "regulation of Ral protein signal transduction", "id": "GO:0032485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032485", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUI1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUI1" } ], "pmid": "" }, { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUI1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUI1" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUI1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUI1" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUI1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUI1" } ], "pmid": "" } ], "molecular_function": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUI1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUI1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I5ZUI1-1", "start_pos": "331", "end_pos": "331", "site_lbl": "Thr331", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 331, "start_aa": "Thr", "end_pos": 331, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr331", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I5ZUI1-1" }, { "uniprot_canonical_ac": "A0A8I6AHS8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHS8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHS8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 414, "chemical_mass": 45088.0, "gene_names": "Scml4;Scml4", "protein_name": "", "disease": [], "molecular_function": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHS8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHS8" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHS8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHS8" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHS8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHS8" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHS8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHS8" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHS8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHS8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AHS8-1" }, { "uniprot_canonical_ac": "A0A8I6AIZ4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AIZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AIZ4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 461, "chemical_mass": 51469.0, "gene_names": "Btbd3;Btbd3", "protein_name": "", "disease": [], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AIZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AIZ4" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AIZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AIZ4" } ], "pmid": "" } ], "biological_process": [ { "name": "cerebral cortex development", "id": "GO:0021987", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021987", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AIZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AIZ4" } ], "pmid": "" }, { "name": "dendrite morphogenesis", "id": "GO:0048813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048813", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AIZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AIZ4" } ], "pmid": "" }, { "name": "neurogenesis", "id": "GO:0022008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022008", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AIZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AIZ4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AIZ4-1" }, { "uniprot_canonical_ac": "A0A8I5ZTN5-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTN5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTN5" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 484, "chemical_mass": 54852.0, "gene_names": "Adsl;Adsl", "protein_name": "Adenylosuccinate lyase", "disease": [ { "disease_id": "DOID:0050762", "name": "adenylosuccinase lyase deficiency", "description": "An amino acid metabolic disorder that is characterized by microcephaly, aggressive behavior, cerebellar hypoplasia and seizures, has_material_basis_in autosomal recessive inheritance of mutation in the ADSL gene resulting in adenylosuccinate lyase deficiency.", "url": "https://disease-ontology.org/term/DOID:0050762", "evidence": [ { "id": "0050762", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050762" } ], "weight": 0.0 }, { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "lyase activity", "id": "GO:0016829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTN5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTN5" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTN5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTN5" } ], "pmid": "" }, { "name": "N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity", "id": "GO:0004018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004018", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTN5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTN5" } ], "pmid": "" }, { "name": "(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity", "id": "GO:0070626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070626", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTN5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTN5" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTN5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTN5" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTN5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTN5" } ], "pmid": "" } ], "biological_process": [ { "name": "response to nutrient", "id": "GO:0007584", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007584", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTN5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTN5" } ], "pmid": "" }, { "name": "response to starvation", "id": "GO:0042594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042594", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTN5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTN5" } ], "pmid": "" }, { "name": "response to hypoxia", "id": "GO:0001666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001666", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTN5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTN5" } ], "pmid": "" }, { "name": "response to muscle activity", "id": "GO:0014850", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014850", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTN5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTN5" } ], "pmid": "" }, { "name": "GMP biosynthetic process", "id": "GO:0006177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006177", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTN5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTN5" } ], "pmid": "" }, { "name": "AMP biosynthetic process", "id": "GO:0006167", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006167", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTN5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTN5" } ], "pmid": "" }, { "name": "aerobic respiration", "id": "GO:0009060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009060", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTN5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTN5" } ], "pmid": "" }, { "name": "'de novo' IMP biosynthetic process", "id": "GO:0006189", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006189", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTN5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTN5" } ], "pmid": "" }, { "name": "'de novo' AMP biosynthetic process", "id": "GO:0044208", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044208", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTN5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTN5" } ], "pmid": "" }, { "name": "'de novo' XMP biosynthetic process", "id": "GO:0097294", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097294", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTN5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTN5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZTN5-1" }, { "uniprot_canonical_ac": "A0A8I6GAY3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GAY3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GAY3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 196, "chemical_mass": 20732.0, "gene_names": "Gng12", "protein_name": "Guanine nucleotide-binding protein subunit gamma", "disease": [ { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "phosphate ion binding", "id": "GO:0042301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042301", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GAY3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GAY3" } ], "pmid": "" }, { "name": "G-protein beta-subunit binding", "id": "GO:0031681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031681", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GAY3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GAY3" } ], "pmid": "" }, { "name": "PDZ domain binding", "id": "GO:0030165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030165", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GAY3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GAY3" } ], "pmid": "" } ], "cellular_component": [ { "name": "actin filament", "id": "GO:0005884", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005884", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GAY3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GAY3" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GAY3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GAY3" } ], "pmid": "" }, { "name": "heterotrimeric G-protein complex", "id": "GO:0005834", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005834", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GAY3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GAY3" } ], "pmid": "" } ], "biological_process": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GAY3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GAY3" } ], "pmid": "" }, { "name": "response to lipopolysaccharide", "id": "GO:0032496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032496", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GAY3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GAY3" } ], "pmid": "" }, { "name": "cerebral cortex development", "id": "GO:0021987", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021987", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GAY3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GAY3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6GAY3-1" }, { "uniprot_canonical_ac": "A0A8I6AV25-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AV25", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AV25" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 195, "chemical_mass": 21328.0, "gene_names": "Zswim7", "protein_name": "", "disease": [ { "disease_id": "DOID:0061014", "name": "ovarian dysgenesis 10", "description": "A 46 XX gonadal dysgenesis characterized by primary amenorrhea and absent puberty that has_material_basis_in homozygous mutation in the ZSWIM7 gene on chromosome 17p12.", "url": "https://disease-ontology.org/term/DOID:0061014", "evidence": [ { "id": "0061014", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061014" } ], "weight": 0.0 }, { "disease_id": "DOID:0070570", "name": "spermatogenic failure 71", "description": "A spermatogenic failure characterized by nonobstructive azoospermia that has_material_basis_in homozygous mutation in the ZSWIM7 gene on chromosome 17p12.", "url": "https://disease-ontology.org/term/DOID:0070570", "evidence": [ { "id": "0070570", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070570" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AV25", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AV25" } ], "pmid": "" } ], "biological_process": [ { "name": "protein stabilization", "id": "GO:0050821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050821", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AV25", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AV25" } ], "pmid": "" }, { "name": "double-strand break repair via homologous recombination", "id": "GO:0000724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000724", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AV25", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AV25" } ], "pmid": "" } ], "cellular_component": [ { "name": "Shu complex", "id": "GO:0097196", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097196", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AV25", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AV25" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AV25-1" }, { "uniprot_canonical_ac": "F7FHM1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F7FHM1", "url": "https://www.uniprot.org/uniprotkb/F7FHM1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 212, "chemical_mass": 23009.0, "gene_names": "Ppic;Ppic", "protein_name": "Peptidyl-prolyl cis-trans isomerase", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F7FHM1", "url": "https://www.uniprot.org/uniprotkb/F7FHM1" } ], "pmid": "" } ], "biological_process": [ { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "F7FHM1", "url": "https://www.uniprot.org/uniprotkb/F7FHM1" } ], "pmid": "" } ], "molecular_function": [ { "name": "cyclosporin A binding", "id": "GO:0016018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016018", "evidence": [ { "database": "UniProtKB", "id": "F7FHM1", "url": "https://www.uniprot.org/uniprotkb/F7FHM1" } ], "pmid": "" }, { "name": "peptidyl-prolyl cis-trans isomerase activity", "id": "GO:0003755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003755", "evidence": [ { "database": "UniProtKB", "id": "F7FHM1", "url": "https://www.uniprot.org/uniprotkb/F7FHM1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F7FHM1-1" }, { "uniprot_canonical_ac": "A0A8I6AU47-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AU47", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AU47" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 314, "chemical_mass": 35782.0, "gene_names": "Or6c6b;Or6c6f;Or6c6h;Or6c6i;Olr951;Olr962;Or6c6b;Or6c6h;Or6c6i;ratchr7-4859164-4858220_ORF", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AU47", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AU47" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AU47", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AU47" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AU47", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AU47" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AU47-1" }, { "uniprot_canonical_ac": "A0A8I6AHA3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHA3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHA3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 471, "chemical_mass": 53361.0, "gene_names": "Mettl4;Mettl4;RGD1306451", "protein_name": "", "disease": [], "cellular_component": [ { "name": "RNA N6-methyladenosine methyltransferase complex", "id": "GO:0036396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036396", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHA3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHA3" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHA3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHA3" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHA3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHA3" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHA3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHA3" } ], "pmid": "" } ], "molecular_function": [ { "name": "site-specific DNA-methyltransferase (adenine-specific) activity", "id": "GO:0009007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009007", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHA3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHA3" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHA3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHA3" } ], "pmid": "" }, { "name": "RNA methyltransferase activity", "id": "GO:0008173", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008173", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHA3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHA3" } ], "pmid": "" } ], "biological_process": [ { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHA3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHA3" } ], "pmid": "" }, { "name": "regulation of RNA splicing", "id": "GO:0043484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043484", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHA3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHA3" } ], "pmid": "" }, { "name": "negative regulation of gene expression, epigenetic", "id": "GO:0045814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045814", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHA3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHA3" } ], "pmid": "" }, { "name": "regulation of mitochondrial DNA replication", "id": "GO:0090296", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090296", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHA3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHA3" } ], "pmid": "" }, { "name": "snRNA (adenine-N6)-methylation", "id": "GO:0120049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120049", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHA3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHA3" } ], "pmid": "" }, { "name": "RNA stabilization", "id": "GO:0043489", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043489", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHA3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHA3" } ], "pmid": "" }, { "name": "regulation of mitochondrial transcription", "id": "GO:1903108", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903108", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHA3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHA3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AHA3-1" }, { "uniprot_canonical_ac": "A0A8I6AN76-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AN76", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AN76" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1078, "chemical_mass": 122754.0, "gene_names": "Wdr64", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AN76-1" }, { "uniprot_canonical_ac": "A0A8I6B415-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B415", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B415" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 612, "chemical_mass": 68781.0, "gene_names": "Cdc14a;Cdc14a", "protein_name": "", "disease": [ { "disease_id": "DOID:0110491", "name": "autosomal recessive nonsyndromic deafness 32", "description": "An autosomal recessive nonsyndromic deafness that is characterized by prelingual onset with severe to profound, stable hearing loss and male infertility in some affected men that has_material_basis_in mutation in the CDC14A gene on chromosome 1p21.2.", "url": "https://disease-ontology.org/term/DOID:0110491", "evidence": [ { "id": "0110491", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110491" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "spindle pole", "id": "GO:0000922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000922", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B415", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B415" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B415", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B415" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B415", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B415" } ], "pmid": "" }, { "name": "kinocilium", "id": "GO:0060091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060091", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B415", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B415" } ], "pmid": "" }, { "name": "stereocilium tip", "id": "GO:0032426", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032426", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B415", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B415" } ], "pmid": "" }, { "name": "kinociliary basal body", "id": "GO:1902636", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902636", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B415", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B415" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B415", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B415" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B415", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B415" } ], "pmid": "" }, { "name": "mitotic spindle", "id": "GO:0072686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072686", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B415", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B415" } ], "pmid": "" } ], "biological_process": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B415", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B415" } ], "pmid": "" }, { "name": "sensory perception of sound", "id": "GO:0007605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007605", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B415", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B415" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B415", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B415" } ], "pmid": "" }, { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B415", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B415" } ], "pmid": "" }, { "name": "regulation of exit from mitosis", "id": "GO:0007096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007096", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B415", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B415" } ], "pmid": "" }, { "name": "positive regulation of cytokinesis", "id": "GO:0032467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032467", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B415", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B415" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein serine/threonine phosphatase activity", "id": "GO:0004722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004722", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B415", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B415" } ], "pmid": "" }, { "name": "protein tyrosine phosphatase activity", "id": "GO:0004725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004725", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B415", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B415" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6B415-1", "start_pos": "456", "end_pos": "456", "site_lbl": "Thr456", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 456, "start_aa": "Thr", "end_pos": 456, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr456", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6B415-1" }, { "uniprot_canonical_ac": "A0A8I6GAW9-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GAW9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GAW9" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1388, "chemical_mass": 155424.0, "gene_names": "Ube4b;Ube4b;ufd2a", "protein_name": "Ubiquitin conjugation factor E4", "disease": [], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GAW9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GAW9" } ], "pmid": "" }, { "name": "enzyme binding", "id": "GO:0019899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019899", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GAW9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GAW9" } ], "pmid": "" }, { "name": "ATPase binding", "id": "GO:0051117", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051117", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GAW9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GAW9" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GAW9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GAW9" } ], "pmid": "" }, { "name": "ubiquitin-ubiquitin ligase activity", "id": "GO:0034450", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034450", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GAW9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GAW9" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GAW9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GAW9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GAW9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GAW9" } ], "pmid": "" }, { "name": "ubiquitin ligase complex", "id": "GO:0000151", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000151", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GAW9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GAW9" } ], "pmid": "" } ], "biological_process": [ { "name": "neuron projection development", "id": "GO:0031175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031175", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GAW9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GAW9" } ], "pmid": "" }, { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GAW9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GAW9" } ], "pmid": "" }, { "name": "response to UV", "id": "GO:0009411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009411", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GAW9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GAW9" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GAW9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GAW9" } ], "pmid": "" }, { "name": "protein polyubiquitination", "id": "GO:0000209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000209", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GAW9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GAW9" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GAW9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GAW9" } ], "pmid": "" }, { "name": "ERAD pathway", "id": "GO:0036503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036503", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GAW9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GAW9" } ], "pmid": "" }, { "name": "protein autoubiquitination", "id": "GO:0051865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051865", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GAW9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GAW9" } ], "pmid": "" }, { "name": "protein catabolic process", "id": "GO:0030163", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030163", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GAW9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GAW9" } ], "pmid": "" }, { "name": "response to endoplasmic reticulum stress", "id": "GO:0034976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034976", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GAW9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GAW9" } ], "pmid": "" }, { "name": "granzyme-mediated apoptotic signaling pathway", "id": "GO:0008626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008626", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GAW9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GAW9" } ], "pmid": "" }, { "name": "ventricular trabecula myocardium morphogenesis", "id": "GO:0003222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003222", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GAW9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GAW9" } ], "pmid": "" }, { "name": "protein monoubiquitination", "id": "GO:0006513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006513", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GAW9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GAW9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6GAW9-1", "start_pos": "381", "end_pos": "381", "site_lbl": "Thr381", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 381, "start_aa": "Thr", "end_pos": 381, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr381", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6GAW9-1" }, { "uniprot_canonical_ac": "A0A8I6A5D5-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5D5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5D5" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 853, "chemical_mass": 93967.0, "gene_names": "Sh2d3c;NSP3;Sh2d3c", "protein_name": "", "disease": [], "molecular_function": [ { "name": "phosphotyrosine residue binding", "id": "GO:0001784", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001784", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5D5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5D5" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5D5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5D5" } ], "pmid": "" } ], "biological_process": [ { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5D5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5D5" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5D5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5D5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6A5D5-1" }, { "uniprot_canonical_ac": "A0A8I6AHB5-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 544, "chemical_mass": 61057.0, "gene_names": "Bbs4", "protein_name": "BBSome complex member BBS4", "disease": [ { "disease_id": "DOID:0110126", "name": "Bardet-Biedl syndrome 4", "description": "A Bardet-Biedl syndrome that has_material_basis_in homozygous mutation in the BBS4 gene on chromosome 15q24.", "url": "https://disease-ontology.org/term/DOID:0110126", "evidence": [ { "id": "0110126", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110126" } ], "weight": 0.0 }, { "disease_id": "DOID:11981", "name": "morbid obesity", "description": "", "url": "https://disease-ontology.org/term/DOID:11981", "evidence": [ { "id": "11981", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11981" } ], "weight": 0.0 }, { "disease_id": "DOID:1935", "name": "Bardet-Biedl syndrome", "description": "A syndrome that results from mutations in multiple BBS genes affecting cellular cilia structure or function (ciliopathy) resulting in variable presentation and characterized principally by obesity, retinitis pigmentosa,vision loss, polydactyly, mental retardation, hypogonadism, and renal failure in some cases.", "url": "https://disease-ontology.org/term/DOID:1935", "evidence": [ { "id": "1935", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1935" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "biological_process": [ { "name": "lymphocyte homeostasis", "id": "GO:0002260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002260", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "negative regulation of gene expression", "id": "GO:0010629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010629", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "dendrite development", "id": "GO:0016358", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016358", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "adult behavior", "id": "GO:0030534", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030534", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "adipose tissue development", "id": "GO:0060612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060612", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "neuron migration", "id": "GO:0001764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001764", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "regulation of lipid metabolic process", "id": "GO:0019216", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019216", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "hippocampus development", "id": "GO:0021766", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021766", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "cerebral cortex development", "id": "GO:0021987", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021987", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "spermatid development", "id": "GO:0007286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007286", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "photoreceptor cell maintenance", "id": "GO:0045494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045494", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "neural tube closure", "id": "GO:0001843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001843", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "retina homeostasis", "id": "GO:0001895", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001895", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "face development", "id": "GO:0060324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060324", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "Wnt signaling pathway", "id": "GO:0016055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "fat cell differentiation", "id": "GO:0045444", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045444", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "social behavior", "id": "GO:0035176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035176", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "mitotic cytokinesis", "id": "GO:0000281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000281", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "negative regulation of systemic arterial blood pressure", "id": "GO:0003085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003085", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "intracellular protein localization", "id": "GO:0008104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008104", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "negative regulation of GTPase activity", "id": "GO:0034260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034260", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "sensory perception of smell", "id": "GO:0007608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007608", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "regulation of stress fiber assembly", "id": "GO:0051492", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051492", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "photoreceptor cell outer segment organization", "id": "GO:0035845", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035845", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "ventricular system development", "id": "GO:0021591", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021591", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "retinal rod cell development", "id": "GO:0046548", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046548", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "brain morphogenesis", "id": "GO:0048854", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048854", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "centrosome cycle", "id": "GO:0007098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007098", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "non-motile cilium assembly", "id": "GO:1905515", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905515", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "erythrocyte homeostasis", "id": "GO:0034101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034101", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "maintenance of protein location in nucleus", "id": "GO:0051457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051457", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "fat pad development", "id": "GO:0060613", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060613", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "protein localization to cilium", "id": "GO:0061512", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061512", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "B cell homeostasis", "id": "GO:0001782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001782", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "myeloid cell homeostasis", "id": "GO:0002262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002262", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "positive regulation of multicellular organism growth", "id": "GO:0040018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040018", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "leukocyte homeostasis", "id": "GO:0001776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001776", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "regulation of cytokinesis", "id": "GO:0032465", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032465", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "homeostasis of number of cells", "id": "GO:0048872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048872", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "protein localization to centrosome", "id": "GO:0071539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071539", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "gene expression", "id": "GO:0010467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010467", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "negative regulation of actin filament polymerization", "id": "GO:0030837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030837", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "striatum development", "id": "GO:0021756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021756", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "negative regulation of appetite by leptin-mediated signaling pathway", "id": "GO:0038108", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038108", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "regulation of cilium beat frequency involved in ciliary motility", "id": "GO:0060296", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060296", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "microtubule anchoring at centrosome", "id": "GO:0034454", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034454", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "positive regulation of cilium assembly", "id": "GO:0045724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045724", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "regulation of non-motile cilium assembly", "id": "GO:1902855", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902855", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "protein localization to photoreceptor outer segment", "id": "GO:1903546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903546", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "response to leptin", "id": "GO:0044321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044321", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "leptin-mediated signaling pathway", "id": "GO:0033210", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033210", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "sperm flagellum assembly", "id": "GO:0120316", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120316", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "sensory perception", "id": "GO:0007600", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007600", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "cell projection organization", "id": "GO:0030030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030030", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "motile cilium", "id": "GO:0031514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031514", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "photoreceptor inner segment", "id": "GO:0001917", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001917", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "non-motile cilium", "id": "GO:0097730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097730", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "centriolar satellite", "id": "GO:0034451", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034451", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "ciliary membrane", "id": "GO:0060170", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060170", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "photoreceptor connecting cilium", "id": "GO:0032391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032391", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "photoreceptor outer segment", "id": "GO:0001750", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001750", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "BBSome", "id": "GO:0034464", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034464", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "ciliary transition zone", "id": "GO:0035869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035869", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "pericentriolar material", "id": "GO:0000242", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000242", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "beta-tubulin binding", "id": "GO:0048487", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048487", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "alpha-tubulin binding", "id": "GO:0043014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043014", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "RNA polymerase II-specific DNA-binding transcription factor binding", "id": "GO:0061629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061629", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" }, { "name": "dynactin binding", "id": "GO:0034452", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034452", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHB5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AHB5-1" }, { "uniprot_canonical_ac": "A0A8I6APB9-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6APB9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6APB9" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 310, "chemical_mass": 34297.0, "gene_names": "Inka2;Fam212b;Inka2;RGD1306526", "protein_name": "PAK4-inhibitor INKA2", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6APB9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6APB9" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6APB9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6APB9" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6APB9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6APB9" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6APB9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6APB9" } ], "pmid": "" }, { "name": "protein serine/threonine kinase inhibitor activity", "id": "GO:0030291", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030291", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6APB9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6APB9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6APB9-1" }, { "uniprot_canonical_ac": "A0A8I6APS9-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6APS9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6APS9" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1078, "chemical_mass": 115999.0, "gene_names": "Ankrd28", "protein_name": "", "disease": [], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6APS9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6APS9" } ], "pmid": "" }, { "name": "lamellipodium", "id": "GO:0030027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030027", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6APS9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6APS9" } ], "pmid": "" }, { "name": "protein serine/threonine phosphatase complex", "id": "GO:0008287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008287", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6APS9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6APS9" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6APS9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6APS9" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein phosphatase regulator activity", "id": "GO:0019888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019888", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6APS9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6APS9" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of focal adhesion assembly", "id": "GO:0051894", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051894", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6APS9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6APS9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6APS9-1" }, { "uniprot_canonical_ac": "A0A8I6GL93-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GL93", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GL93" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 733, "chemical_mass": 85810.0, "gene_names": "Xpr1", "protein_name": "Solute carrier family 53 member 1", "disease": [ { "disease_id": "DOID:0060230", "name": "basal ganglia calcification", "description": "A basal ganglia disease characterized by the presence of abnormal calcium deposits of unknown cause in the brain; has symptom dementia, psychosis, mood swings and loss of acquired motor skills.", "url": "https://disease-ontology.org/term/DOID:0060230", "evidence": [ { "id": "0060230", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060230" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GL93", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GL93" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GL93", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GL93" } ], "pmid": "" } ], "biological_process": [ { "name": "response to virus", "id": "GO:0009615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009615", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GL93", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GL93" } ], "pmid": "" }, { "name": "phosphate ion transmembrane transport", "id": "GO:0035435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035435", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GL93", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GL93" } ], "pmid": "" }, { "name": "intracellular phosphate ion homeostasis", "id": "GO:0030643", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030643", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GL93", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GL93" } ], "pmid": "" } ], "molecular_function": [ { "name": "virus receptor activity", "id": "GO:0001618", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001618", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GL93", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GL93" } ], "pmid": "" }, { "name": "efflux transmembrane transporter activity", "id": "GO:0015562", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015562", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GL93", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GL93" } ], "pmid": "" }, { "name": "phosphate transmembrane transporter activity", "id": "GO:0005315", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005315", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GL93", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GL93" } ], "pmid": "" }, { "name": "inositol hexakisphosphate binding", "id": "GO:0000822", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000822", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GL93", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GL93" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6GL93-1" }, { "uniprot_canonical_ac": "A0A8L2QL41-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8L2QL41", "url": "https://www.uniprot.org/uniprotkb/A0A8L2QL41" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 561, "chemical_mass": 62603.0, "gene_names": "Ces2f;Ces2f;LOC100910259", "protein_name": "Carboxylic ester hydrolase", "disease": [], "molecular_function": [ { "name": "retinyl-palmitate esterase activity", "id": "GO:0050253", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050253", "evidence": [ { "database": "UniProtKB", "id": "A0A8L2QL41", "url": "https://www.uniprot.org/uniprotkb/A0A8L2QL41" } ], "pmid": "" }, { "name": "carboxylesterase activity", "id": "GO:0106435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106435", "evidence": [ { "database": "UniProtKB", "id": "A0A8L2QL41", "url": "https://www.uniprot.org/uniprotkb/A0A8L2QL41" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8L2QL41-1" }, { "uniprot_canonical_ac": "A0A8I6G9L9-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G9L9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G9L9" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 608, "chemical_mass": 65668.0, "gene_names": "Prss56", "protein_name": "Serine protease 56", "disease": [ { "disease_id": "DOID:0060835", "name": "isolated microphthalmia 6", "description": "An isolated microphthalmia characterized by autosomal recessive inheritance reduction in eye size that is restricted to the posterior segment of the eye, extreme hyperopia, and short axial length that has_material_basis_in homozygous or compound heterozygous mutation in the PRSS56 gene on chromosome 2q37.", "url": "https://disease-ontology.org/term/DOID:0060835", "evidence": [ { "id": "0060835", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060835" } ], "weight": 0.0 }, { "disease_id": "DOID:0080634", "name": "nanophthalmos", "description": "A microphthalmia that is characterized by a small eye with a short axial length, severe hyperopia, an elevated lens/eye ratio, and a high incidence of angle-closure glaucoma.", "url": "https://disease-ontology.org/term/DOID:0080634", "evidence": [ { "id": "0080634", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080634" } ], "weight": 0.0 }, { "disease_id": "DOID:13550", "name": "angle-closure glaucoma", "description": "A glaucoma characterized by closure of the anterior chamber angle such that aqueous outflow is blocked and the intraocular pressure becomes inappropriately elevated leading to optic nerve damage and visual field loss. Angle-closure glaucoma has_symptom progressive peripheral vision loss, decreased vision, and pain, redness, and headache in acute cases. Angle closure glaucoma can be caused by anatomically narrow angle, injury to the trabecular meshwork, and injuries to the anterior chamber, such as neovascularization and uveitis.", "url": "https://disease-ontology.org/term/DOID:13550", "evidence": [ { "id": "13550", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13550" } ], "weight": 0.0 }, { "disease_id": "DOID:4947", "name": "cholangiocarcinoma", "description": "A bile duct adenocarcinoma that has_material_basis_in bile duct epithelial cells.", "url": "https://disease-ontology.org/term/DOID:4947", "evidence": [ { "id": "4947", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4947" } ], "weight": 0.0 }, { "disease_id": "DOID:9835", "name": "refractive error", "description": "", "url": "https://disease-ontology.org/term/DOID:9835", "evidence": [ { "id": "9835", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9835" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G9L9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G9L9" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G9L9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G9L9" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G9L9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G9L9" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G9L9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G9L9" } ], "pmid": "" }, { "name": "camera-type eye development", "id": "GO:0043010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043010", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G9L9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G9L9" } ], "pmid": "" }, { "name": "blood coagulation", "id": "GO:0007596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007596", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G9L9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G9L9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6G9L9-1" }, { "uniprot_canonical_ac": "A0A8I6ANZ5-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ANZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ANZ5" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 2068, "chemical_mass": 235877.0, "gene_names": "Loxhd1", "protein_name": "", "disease": [ { "disease_id": "DOID:0050567", "name": "orofacial cleft", "description": "A physical disorder that is characterized by cleft lip and/or cleft palate that result in feeding, speech and hearing problems caused by failures during development.", "url": "https://disease-ontology.org/term/DOID:0050567", "evidence": [ { "id": "0050567", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050567" } ], "weight": 0.0 }, { "disease_id": "DOID:0110525", "name": "autosomal recessive nonsyndromic deafness 77", "description": "An autosomal recessive nonsyndromic deafness that is characterized by postlingual onset with moderate to profound, progressive hearing loss and has_material_basis_in mutation in the LOXHD1 gene on chromosome 18q21.", "url": "https://disease-ontology.org/term/DOID:0110525", "evidence": [ { "id": "0110525", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110525" } ], "weight": 0.0 }, { "disease_id": "DOID:11555", "name": "Fuchs' endothelial dystrophy", "description": "A corneal dystrophy characterized by accumulation of focal outgrowths (guttae) and thickening of Descemet's membrane, leading to corneal edema and loss of vision.", "url": "https://disease-ontology.org/term/DOID:11555", "evidence": [ { "id": "11555", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11555" } ], "weight": 0.0 } ], "biological_process": [ { "name": "sensory perception of sound", "id": "GO:0007605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007605", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ANZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ANZ5" } ], "pmid": "" } ], "cellular_component": [ { "name": "stereocilium", "id": "GO:0032420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032420", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ANZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ANZ5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6ANZ5-1", "start_pos": "1429", "end_pos": "1429", "site_lbl": "Thr1429", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1429, "start_aa": "Thr", "end_pos": 1429, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1429", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I6ANZ5-1", "start_pos": "545", "end_pos": "545", "site_lbl": "Thr545", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 545, "start_aa": "Thr", "end_pos": 545, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr545", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I6ANZ5-1", "start_pos": "558", "end_pos": "558", "site_lbl": "Thr558", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 558, "start_aa": "Thr", "end_pos": 558, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr558", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6ANZ5-1" }, { "uniprot_canonical_ac": "A0A8I6ATJ1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATJ1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 843, "chemical_mass": 94829.0, "gene_names": "Ece2", "protein_name": "endothelin-converting enzyme 1", "disease": [], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATJ1" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATJ1" } ], "pmid": "" }, { "name": "transport vesicle membrane", "id": "GO:0030658", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030658", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATJ1" } ], "pmid": "" }, { "name": "cytoplasmic vesicle membrane", "id": "GO:0030659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030659", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATJ1" } ], "pmid": "" } ], "molecular_function": [ { "name": "metalloendopeptidase activity", "id": "GO:0004222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004222", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATJ1" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATJ1" } ], "pmid": "" }, { "name": "metallopeptidase activity", "id": "GO:0008237", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008237", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATJ1" } ], "pmid": "" } ], "biological_process": [ { "name": "protein processing", "id": "GO:0016485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016485", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATJ1" } ], "pmid": "" }, { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATJ1" } ], "pmid": "" }, { "name": "peptide hormone processing", "id": "GO:0016486", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016486", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATJ1" } ], "pmid": "" }, { "name": "brain development", "id": "GO:0007420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATJ1" } ], "pmid": "" }, { "name": "cardioblast differentiation", "id": "GO:0010002", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010002", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATJ1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6ATJ1-1" }, { "uniprot_canonical_ac": "A0A8I6AM38-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AM38", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AM38" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1575, "chemical_mass": 180649.0, "gene_names": "Iqgap2;Iqgap2;LOC100360623", "protein_name": "", "disease": [ { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AM38", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AM38" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AM38", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AM38" } ], "pmid": "" }, { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AM38", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AM38" } ], "pmid": "" }, { "name": "phosphatidylinositol-3,4,5-trisphosphate binding", "id": "GO:0005547", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005547", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AM38", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AM38" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AM38", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AM38" } ], "pmid": "" }, { "name": "Arp2/3 complex binding", "id": "GO:0071933", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071933", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AM38", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AM38" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AM38", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AM38" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AM38", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AM38" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AM38", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AM38" } ], "pmid": "" }, { "name": "cell leading edge", "id": "GO:0031252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031252", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AM38", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AM38" } ], "pmid": "" }, { "name": "plasma membrane bounded cell projection", "id": "GO:0120025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120025", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AM38", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AM38" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AM38", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AM38" } ], "pmid": "" }, { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AM38", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AM38" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AM38", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AM38" } ], "pmid": "" }, { "name": "lamellipodium", "id": "GO:0030027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030027", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AM38", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AM38" } ], "pmid": "" }, { "name": "filopodium", "id": "GO:0030175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030175", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AM38", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AM38" } ], "pmid": "" }, { "name": "microvillus", "id": "GO:0005902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005902", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AM38", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AM38" } ], "pmid": "" } ], "biological_process": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AM38", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AM38" } ], "pmid": "" }, { "name": "regulation of actin cytoskeleton organization", "id": "GO:0032956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032956", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AM38", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AM38" } ], "pmid": "" }, { "name": "Arp2/3 complex-mediated actin nucleation", "id": "GO:0034314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034314", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AM38", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AM38" } ], "pmid": "" }, { "name": "thrombin-activated receptor signaling pathway", "id": "GO:0070493", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070493", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AM38", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AM38" } ], "pmid": "" }, { "name": "mitotic actomyosin contractile ring assembly actin filament organization", "id": "GO:1903479", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903479", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AM38", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AM38" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AM38-1" }, { "uniprot_canonical_ac": "A0A8I6G9X6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G9X6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G9X6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 2205, "chemical_mass": 250570.0, "gene_names": "Kntc1;Kntc1", "protein_name": "", "disease": [], "cellular_component": [ { "name": "kinetochore microtubule", "id": "GO:0005828", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005828", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G9X6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G9X6" } ], "pmid": "" }, { "name": "RZZ complex", "id": "GO:1990423", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990423", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G9X6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G9X6" } ], "pmid": "" }, { "name": "spindle pole", "id": "GO:0000922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000922", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G9X6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G9X6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G9X6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G9X6" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G9X6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G9X6" } ], "pmid": "" } ], "biological_process": [ { "name": "protein localization to kinetochore involved in kinetochore assembly", "id": "GO:1903394", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903394", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G9X6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G9X6" } ], "pmid": "" }, { "name": "mitotic spindle assembly checkpoint signaling", "id": "GO:0007094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007094", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G9X6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G9X6" } ], "pmid": "" }, { "name": "mitotic sister chromatid segregation", "id": "GO:0000070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000070", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G9X6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G9X6" } ], "pmid": "" } ], "molecular_function": [ { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G9X6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G9X6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6G9X6-1", "start_pos": "1039", "end_pos": "1039", "site_lbl": "Thr1039", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1039, "start_aa": "Thr", "end_pos": 1039, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1039", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6G9X6-1" }, { "uniprot_canonical_ac": "A0A8I6AVA2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AVA2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AVA2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 772, "chemical_mass": 87516.0, "gene_names": "Gcfc2;Gcfc2;RGD1304792", "protein_name": "", "disease": [], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AVA2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AVA2" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AVA2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AVA2" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AVA2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AVA2" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AVA2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AVA2" } ], "pmid": "" }, { "name": "U2-type post-mRNA release spliceosomal complex", "id": "GO:0071008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071008", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AVA2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AVA2" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AVA2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AVA2" } ], "pmid": "" }, { "name": "spliceosomal complex assembly", "id": "GO:0000245", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000245", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AVA2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AVA2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AVA2-1" }, { "uniprot_canonical_ac": "A0A1W2Q626-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A1W2Q626", "url": "https://www.uniprot.org/uniprotkb/A0A1W2Q626" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 834, "chemical_mass": 94307.0, "gene_names": "Slc39a10;Slc39a10", "protein_name": "", "disease": [], "molecular_function": [ { "name": "zinc ion transmembrane transporter activity", "id": "GO:0005385", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005385", "evidence": [ { "database": "UniProtKB", "id": "A0A1W2Q626", "url": "https://www.uniprot.org/uniprotkb/A0A1W2Q626" } ], "pmid": "" }, { "name": "protein tyrosine phosphatase activator activity", "id": "GO:0008160", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008160", "evidence": [ { "database": "UniProtKB", "id": "A0A1W2Q626", "url": "https://www.uniprot.org/uniprotkb/A0A1W2Q626" } ], "pmid": "" }, { "name": "monoatomic cation:bicarbonate symporter activity", "id": "GO:0140410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140410", "evidence": [ { "database": "UniProtKB", "id": "A0A1W2Q626", "url": "https://www.uniprot.org/uniprotkb/A0A1W2Q626" } ], "pmid": "" } ], "cellular_component": [ { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "A0A1W2Q626", "url": "https://www.uniprot.org/uniprotkb/A0A1W2Q626" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A1W2Q626", "url": "https://www.uniprot.org/uniprotkb/A0A1W2Q626" } ], "pmid": "" } ], "biological_process": [ { "name": "epithelial to mesenchymal transition", "id": "GO:0001837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001837", "evidence": [ { "database": "UniProtKB", "id": "A0A1W2Q626", "url": "https://www.uniprot.org/uniprotkb/A0A1W2Q626" } ], "pmid": "" }, { "name": "zinc ion transmembrane transport", "id": "GO:0071577", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071577", "evidence": [ { "database": "UniProtKB", "id": "A0A1W2Q626", "url": "https://www.uniprot.org/uniprotkb/A0A1W2Q626" } ], "pmid": "" }, { "name": "positive regulation of B cell proliferation", "id": "GO:0030890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030890", "evidence": [ { "database": "UniProtKB", "id": "A0A1W2Q626", "url": "https://www.uniprot.org/uniprotkb/A0A1W2Q626" } ], "pmid": "" }, { "name": "intracellular zinc ion homeostasis", "id": "GO:0006882", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006882", "evidence": [ { "database": "UniProtKB", "id": "A0A1W2Q626", "url": "https://www.uniprot.org/uniprotkb/A0A1W2Q626" } ], "pmid": "" }, { "name": "intracellular monoatomic cation homeostasis", "id": "GO:0030003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030003", "evidence": [ { "database": "UniProtKB", "id": "A0A1W2Q626", "url": "https://www.uniprot.org/uniprotkb/A0A1W2Q626" } ], "pmid": "" }, { "name": "zinc ion import across plasma membrane", "id": "GO:0071578", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071578", "evidence": [ { "database": "UniProtKB", "id": "A0A1W2Q626", "url": "https://www.uniprot.org/uniprotkb/A0A1W2Q626" } ], "pmid": "" }, { "name": "negative regulation of B cell apoptotic process", "id": "GO:0002903", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002903", "evidence": [ { "database": "UniProtKB", "id": "A0A1W2Q626", "url": "https://www.uniprot.org/uniprotkb/A0A1W2Q626" } ], "pmid": "" }, { "name": "positive regulation of B cell receptor signaling pathway", "id": "GO:0050861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050861", "evidence": [ { "database": "UniProtKB", "id": "A0A1W2Q626", "url": "https://www.uniprot.org/uniprotkb/A0A1W2Q626" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A1W2Q626-1", "start_pos": "324", "end_pos": "324", "site_lbl": "Thr324", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 324, "start_aa": "Thr", "end_pos": 324, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr324", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A1W2Q626-1" }, { "uniprot_canonical_ac": "A0A8I6G5Q1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G5Q1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G5Q1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 862, "chemical_mass": 95817.0, "gene_names": "Sema4d;Sema4d", "protein_name": "Semaphorin-4D", "disease": [], "biological_process": [ { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G5Q1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G5Q1" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G5Q1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G5Q1" } ], "pmid": "" }, { "name": "regulation of plasma membrane bounded cell projection organization", "id": "GO:0120035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120035", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G5Q1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G5Q1" } ], "pmid": "" }, { "name": "regulation of cell projection organization", "id": "GO:0031344", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031344", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G5Q1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G5Q1" } ], "pmid": "" }, { "name": "ossification involved in bone maturation", "id": "GO:0043931", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043931", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G5Q1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G5Q1" } ], "pmid": "" }, { "name": "bone trabecula morphogenesis", "id": "GO:0061430", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061430", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G5Q1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G5Q1" } ], "pmid": "" }, { "name": "leukocyte aggregation", "id": "GO:0070486", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070486", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G5Q1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G5Q1" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G5Q1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G5Q1" } ], "pmid": "" }, { "name": "positive regulation of protein phosphorylation", "id": "GO:0001934", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001934", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G5Q1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G5Q1" } ], "pmid": "" }, { "name": "negative regulation of cell adhesion", "id": "GO:0007162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007162", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G5Q1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G5Q1" } ], "pmid": "" }, { "name": "positive regulation of cell migration", "id": "GO:0030335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030335", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G5Q1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G5Q1" } ], "pmid": "" }, { "name": "positive regulation of GTPase activity", "id": "GO:0043547", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043547", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G5Q1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G5Q1" } ], "pmid": "" }, { "name": "regulation of dendrite morphogenesis", "id": "GO:0048814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048814", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G5Q1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G5Q1" } ], "pmid": "" }, { "name": "positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction", "id": "GO:0051897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051897", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G5Q1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G5Q1" } ], "pmid": "" }, { "name": "semaphorin-plexin signaling pathway", "id": "GO:0071526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071526", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G5Q1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G5Q1" } ], "pmid": "" }, { "name": "neural crest cell migration", "id": "GO:0001755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001755", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G5Q1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G5Q1" } ], "pmid": "" }, { "name": "regulation of synapse assembly", "id": "GO:0051963", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051963", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G5Q1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G5Q1" } ], "pmid": "" }, { "name": "positive regulation of Rho protein signal transduction", "id": "GO:0035025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035025", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G5Q1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G5Q1" } ], "pmid": "" }, { "name": "regulation of cell shape", "id": "GO:0008360", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008360", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G5Q1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G5Q1" } ], "pmid": "" }, { "name": "positive regulation of axonogenesis", "id": "GO:0050772", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050772", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G5Q1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G5Q1" } ], "pmid": "" }, { "name": "negative chemotaxis", "id": "GO:0050919", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050919", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G5Q1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G5Q1" } ], "pmid": "" }, { "name": "negative regulation of osteoblast differentiation", "id": "GO:0045668", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045668", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G5Q1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G5Q1" } ], "pmid": "" }, { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G5Q1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G5Q1" } ], "pmid": "" }, { "name": "positive regulation of collateral sprouting", "id": "GO:0048672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048672", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G5Q1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G5Q1" } ], "pmid": "" }, { "name": "positive regulation of inhibitory synapse assembly", "id": "GO:1905704", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905704", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G5Q1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G5Q1" } ], "pmid": "" }, { "name": "positive regulation of intracellular signal transduction", "id": "GO:1902533", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902533", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G5Q1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G5Q1" } ], "pmid": "" } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G5Q1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G5Q1" } ], "pmid": "" }, { "name": "GABA-ergic synapse", "id": "GO:0098982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098982", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G5Q1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G5Q1" } ], "pmid": "" }, { "name": "semaphorin receptor complex", "id": "GO:0002116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002116", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G5Q1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G5Q1" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G5Q1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G5Q1" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G5Q1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G5Q1" } ], "pmid": "" }, { "name": "postsynaptic membrane", "id": "GO:0045211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045211", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G5Q1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G5Q1" } ], "pmid": "" } ], "molecular_function": [ { "name": "semaphorin receptor binding", "id": "GO:0030215", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030215", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G5Q1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G5Q1" } ], "pmid": "" }, { "name": "transmembrane signaling receptor activity", "id": "GO:0004888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004888", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G5Q1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G5Q1" } ], "pmid": "" }, { "name": "signaling receptor binding", "id": "GO:0005102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005102", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G5Q1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G5Q1" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G5Q1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G5Q1" } ], "pmid": "" }, { "name": "neuropilin binding", "id": "GO:0038191", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038191", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G5Q1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G5Q1" } ], "pmid": "" }, { "name": "chemorepellent activity", "id": "GO:0045499", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045499", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G5Q1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G5Q1" } ], "pmid": "" }, { "name": "receptor ligand activity", "id": "GO:0048018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048018", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G5Q1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G5Q1" } ], "pmid": "" }, { "name": "signaling receptor activity", "id": "GO:0038023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038023", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G5Q1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G5Q1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6G5Q1-1", "start_pos": "364", "end_pos": "364", "site_lbl": "Thr364", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 364, "start_aa": "Thr", "end_pos": 364, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr364", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I6G5Q1-1", "start_pos": "657", "end_pos": "657", "site_lbl": "Thr657", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 657, "start_aa": "Thr", "end_pos": 657, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr657", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I6G5Q1-1", "start_pos": "684", "end_pos": "684", "site_lbl": "Thr684", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 684, "start_aa": "Thr", "end_pos": 684, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr684", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6G5Q1-1" }, { "uniprot_canonical_ac": "A0A8I6ANV3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ANV3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ANV3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 2363, "chemical_mass": 252942.0, "gene_names": "Nav3;Nav3;RGD1306259", "protein_name": "Neuron navigator 3", "disease": [ { "disease_id": "DOID:0070338", "name": "cerebellar hypoplasia", "description": "A cerebellar disease that is characterized by a cerebellum that is smaller than usual or not completely developed.", "url": "https://disease-ontology.org/term/DOID:0070338", "evidence": [ { "id": "0070338", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070338" } ], "weight": 0.0 }, { "disease_id": "DOID:2559", "name": "opiate dependence", "description": "A drug dependence that involves the continued use of opiate drugs despite despite problems related to use of the substance.", "url": "https://disease-ontology.org/term/DOID:2559", "evidence": [ { "id": "2559", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2559" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ANV3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ANV3" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ANV3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ANV3" } ], "pmid": "" }, { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ANV3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ANV3" } ], "pmid": "" } ], "biological_process": [ { "name": "neurogenesis", "id": "GO:0022008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022008", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ANV3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ANV3" } ], "pmid": "" }, { "name": "negative regulation of interleukin-2 production", "id": "GO:0032703", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032703", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ANV3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ANV3" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ANV3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ANV3" } ], "pmid": "" }, { "name": "negative regulation of cell migration", "id": "GO:0030336", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030336", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ANV3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ANV3" } ], "pmid": "" }, { "name": "negative regulation of microtubule depolymerization", "id": "GO:0007026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007026", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ANV3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ANV3" } ], "pmid": "" }, { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ANV3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ANV3" } ], "pmid": "" }, { "name": "positive regulation of microtubule polymerization", "id": "GO:0031116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031116", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ANV3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ANV3" } ], "pmid": "" } ], "cellular_component": [ { "name": "nuclear outer membrane", "id": "GO:0005640", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005640", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ANV3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ANV3" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ANV3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ANV3" } ], "pmid": "" }, { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ANV3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ANV3" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ANV3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ANV3" } ], "pmid": "" }, { "name": "microtubule end", "id": "GO:1990752", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990752", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ANV3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ANV3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6ANV3-1", "start_pos": "360", "end_pos": "360", "site_lbl": "Thr360", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 360, "start_aa": "Thr", "end_pos": 360, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr360", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6ANV3-1" }, { "uniprot_canonical_ac": "A0A8I6GCQ3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GCQ3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GCQ3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1101, "chemical_mass": 123447.0, "gene_names": "Ano8", "protein_name": "Anoctamin", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GCQ3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GCQ3" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GCQ3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GCQ3" } ], "pmid": "" } ], "molecular_function": [ { "name": "intracellularly calcium-gated chloride channel activity", "id": "GO:0005229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005229", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GCQ3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GCQ3" } ], "pmid": "" } ], "biological_process": [ { "name": "chloride transmembrane transport", "id": "GO:1902476", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902476", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GCQ3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GCQ3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6GCQ3-1" }, { "uniprot_canonical_ac": "A0A8I6AWM3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AWM3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AWM3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 2329, "chemical_mass": 268025.0, "gene_names": "Sptb;Spnb1;Sptb", "protein_name": "Spectrin beta chain", "disease": [ { "disease_id": "DOID:0050882", "name": "spinocerebellar ataxia 5", "description": "An autosomal dominant cerebellar ataxia that is characterized by the early-onset of cerebellar signs and eye movement abnormalities with a very slow disease progression, and has_material_basis_in mutation in the SPTBN2 gene.", "url": "https://disease-ontology.org/term/DOID:0050882", "evidence": [ { "id": "0050882", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050882" } ], "weight": 0.0 }, { "disease_id": "DOID:0110917", "name": "hereditary spherocytosis type 2", "description": "A hereditary spherocytosis that has_material_basis_in an autosomal dominant mutation of the SPTB gene on chromosome 14q23.3.", "url": "https://disease-ontology.org/term/DOID:0110917", "evidence": [ { "id": "0110917", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110917" } ], "weight": 0.0 }, { "disease_id": "DOID:12971", "name": "hereditary spherocytosis", "description": "A congenital hemolytic anemia characterized by the production of red blood cells with a sphere shape, rather than the normal biconcave disk shape.", "url": "https://disease-ontology.org/term/DOID:12971", "evidence": [ { "id": "12971", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12971" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AWM3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AWM3" } ], "pmid": "" }, { "name": "structural constituent of cytoskeleton", "id": "GO:0005200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005200", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AWM3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AWM3" } ], "pmid": "" }, { "name": "phospholipid binding", "id": "GO:0005543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005543", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AWM3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AWM3" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AWM3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AWM3" } ], "pmid": "" }, { "name": "ankyrin binding", "id": "GO:0030506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030506", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AWM3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AWM3" } ], "pmid": "" } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AWM3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AWM3" } ], "pmid": "" }, { "name": "spectrin", "id": "GO:0008091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008091", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AWM3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AWM3" } ], "pmid": "" }, { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AWM3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AWM3" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AWM3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AWM3" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AWM3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AWM3" } ], "pmid": "" }, { "name": "cell junction", "id": "GO:0030054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030054", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AWM3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AWM3" } ], "pmid": "" }, { "name": "postsynapse", "id": "GO:0098794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098794", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AWM3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AWM3" } ], "pmid": "" }, { "name": "spectrin-associated cytoskeleton", "id": "GO:0014731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014731", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AWM3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AWM3" } ], "pmid": "" }, { "name": "cortical cytoskeleton", "id": "GO:0030863", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030863", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AWM3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AWM3" } ], "pmid": "" }, { "name": "cortical actin cytoskeleton", "id": "GO:0030864", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030864", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AWM3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AWM3" } ], "pmid": "" }, { "name": "cell projection", "id": "GO:0042995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042995", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AWM3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AWM3" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AWM3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AWM3" } ], "pmid": "" } ], "biological_process": [ { "name": "actin filament capping", "id": "GO:0051693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051693", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AWM3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AWM3" } ], "pmid": "" }, { "name": "modification of postsynaptic actin cytoskeleton", "id": "GO:0098885", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098885", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AWM3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AWM3" } ], "pmid": "" }, { "name": "plasma membrane organization", "id": "GO:0007009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007009", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AWM3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AWM3" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AWM3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AWM3" } ], "pmid": "" }, { "name": "hemopoiesis", "id": "GO:0030097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030097", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AWM3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AWM3" } ], "pmid": "" }, { "name": "porphyrin-containing compound biosynthetic process", "id": "GO:0006779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006779", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AWM3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AWM3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AWM3-1" }, { "uniprot_canonical_ac": "A0A8I6B1B9-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B1B9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B1B9" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1996, "chemical_mass": 223906.0, "gene_names": "Lrrk1", "protein_name": "Leucine-rich repeat serine/threonine-protein kinase 1", "disease": [ { "disease_id": "DOID:0060371", "name": "Parkinson's disease 8", "description": "A late onset Parkinson's disease that has_material_basis_in heterozygous mutation in the dardarin encoding gene on chromosome 12q12.", "url": "https://disease-ontology.org/term/DOID:0060371", "evidence": [ { "id": "0060371", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060371" } ], "weight": 0.0 }, { "disease_id": "DOID:0060892", "name": "late onset Parkinson's disease", "description": "A Parkinson's disease characterized by onset of motor symptoms typically after 60 years of age.", "url": "https://disease-ontology.org/term/DOID:0060892", "evidence": [ { "id": "0060892", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060892" } ], "weight": 0.0 }, { "disease_id": "DOID:0081111", "name": "osteosclerotic metaphyseal dysplasia", "description": "A metaphyseal dysplasia that is characterized by distinctive radiographic changes, including osteosclerosis localized predominantly to the metaphyses of the long bones and that has_material_basis_in homozygous mutation in the LRRK1 gene on chromosome 15q26.", "url": "https://disease-ontology.org/term/DOID:0081111", "evidence": [ { "id": "0081111", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081111" } ], "weight": 0.0 }, { "disease_id": "DOID:13533", "name": "osteopetrosis", "description": "An osteosclerosis that has_material_basis_in lack of bone resorption which results_in abnormally hard and brittle bones.", "url": "https://disease-ontology.org/term/DOID:13533", "evidence": [ { "id": "13533", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13533" } ], "weight": 0.0 }, { "disease_id": "DOID:14330", "name": "Parkinson's disease", "description": "A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.", "url": "https://disease-ontology.org/term/DOID:14330", "evidence": [ { "id": "14330", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14330" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B1B9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B1B9" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B1B9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B1B9" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B1B9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B1B9" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B1B9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B1B9" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B1B9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B1B9" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B1B9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B1B9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B1B9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B1B9" } ], "pmid": "" } ], "biological_process": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B1B9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B1B9" } ], "pmid": "" }, { "name": "positive regulation of peptidyl-tyrosine phosphorylation", "id": "GO:0050731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050731", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B1B9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B1B9" } ], "pmid": "" }, { "name": "bone resorption", "id": "GO:0045453", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045453", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B1B9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B1B9" } ], "pmid": "" }, { "name": "osteoclast development", "id": "GO:0036035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036035", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B1B9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B1B9" } ], "pmid": "" }, { "name": "positive regulation of canonical Wnt signaling pathway", "id": "GO:0090263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090263", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B1B9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B1B9" } ], "pmid": "" }, { "name": "positive regulation of intracellular signal transduction", "id": "GO:1902533", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902533", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B1B9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B1B9" } ], "pmid": "" }, { "name": "negative regulation of peptidyl-tyrosine phosphorylation", "id": "GO:0050732", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050732", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B1B9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B1B9" } ], "pmid": "" }, { "name": "regulation of signal transduction", "id": "GO:0009966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009966", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B1B9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B1B9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6B1B9-1", "start_pos": "1410", "end_pos": "1410", "site_lbl": "Thr1410", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1410, "start_aa": "Thr", "end_pos": 1410, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1410", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6B1B9-1" }, { "uniprot_canonical_ac": "A0A8I6AD71-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AD71", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AD71" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 849, "chemical_mass": 94738.0, "gene_names": "Rsbn1l;RGD1308748;Rsbn1l", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AD71", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AD71" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AD71", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AD71" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein demethylase activity", "id": "GO:0140457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140457", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AD71", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AD71" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6AD71-1", "start_pos": "142", "end_pos": "142", "site_lbl": "Thr142", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 142, "start_aa": "Thr", "end_pos": 142, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr142", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I6AD71-1", "start_pos": "239", "end_pos": "239", "site_lbl": "Thr239", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 239, "start_aa": "Thr", "end_pos": 239, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr239", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I6AD71-1", "start_pos": "724", "end_pos": "724", "site_lbl": "Thr724", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 724, "start_aa": "Thr", "end_pos": 724, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr724", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6AD71-1" }, { "uniprot_canonical_ac": "A0A8I6AS17-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AS17", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AS17" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 434, "chemical_mass": 47785.0, "gene_names": "Bsdc1", "protein_name": "", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AS17", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AS17" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AS17", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AS17" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6AS17-1", "start_pos": "279", "end_pos": "279", "site_lbl": "Thr279", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" }, { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "reported site T272 is on non-canonical isoform D4A3M7-1 which maps to canonical isoform site A0A8I6AS17-1:279", "icn3d_view": {}, "start_pos": 279, "start_aa": "Thr", "end_pos": 279, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr279", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6AS17-1" }, { "uniprot_canonical_ac": "A0A8I6ASC6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ASC6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ASC6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1253, "chemical_mass": 134702.0, "gene_names": "Igdcc4;Igdcc4;Nope", "protein_name": "Immunoglobulin superfamily DCC subclass member 4", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ASC6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ASC6" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of neurogenesis", "id": "GO:0050768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050768", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ASC6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ASC6" } ], "pmid": "" }, { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ASC6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ASC6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6ASC6-1" }, { "uniprot_canonical_ac": "A0A8I6AR85-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AR85", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AR85" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 504, "chemical_mass": 58258.0, "gene_names": "Cyp3a73;Cyp3a73", "protein_name": "Cytochrome P450 3A", "disease": [], "molecular_function": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AR85", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AR85" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AR85", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AR85" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen", "id": "GO:0016712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016712", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AR85", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AR85" } ], "pmid": "" }, { "name": "steroid hydroxylase activity", "id": "GO:0008395", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008395", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AR85", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AR85" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AR85", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AR85" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AR85-1" }, { "uniprot_canonical_ac": "A0A8I6AHZ6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHZ6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 235, "chemical_mass": 26928.0, "gene_names": "Rasl10b;Rasl10b", "protein_name": "", "disease": [], "molecular_function": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHZ6" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHZ6" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of systemic arterial blood pressure by atrial natriuretic peptide", "id": "GO:0003050", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003050", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHZ6" } ], "pmid": "" }, { "name": "positive regulation of peptide hormone secretion", "id": "GO:0090277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090277", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHZ6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AHZ6-1" }, { "uniprot_canonical_ac": "A0A8I6GLR4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GLR4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GLR4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 233, "chemical_mass": 26853.0, "gene_names": "C19h16orf95;C19h16orf95;LOC687560", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6GLR4-1" }, { "uniprot_canonical_ac": "A0A8I6G3U6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3U6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3U6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1145, "chemical_mass": 131471.0, "gene_names": "Ankrd45;Slc9c2;Ankrd45;RGD1565820;Slc9c2", "protein_name": "Cyclic nucleotide-binding domain-containing protein", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3U6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3U6" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3U6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3U6" } ], "pmid": "" }, { "name": "cleavage furrow", "id": "GO:0032154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032154", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3U6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3U6" } ], "pmid": "" }, { "name": "midbody", "id": "GO:0030496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030496", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3U6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3U6" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3U6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3U6" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3U6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3U6" } ], "pmid": "" } ], "biological_process": [ { "name": "cell population proliferation", "id": "GO:0008283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008283", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3U6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3U6" } ], "pmid": "" }, { "name": "regulation of intracellular pH", "id": "GO:0051453", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051453", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3U6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3U6" } ], "pmid": "" }, { "name": "potassium ion transmembrane transport", "id": "GO:0071805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071805", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3U6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3U6" } ], "pmid": "" }, { "name": "sodium ion import across plasma membrane", "id": "GO:0098719", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098719", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3U6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3U6" } ], "pmid": "" } ], "molecular_function": [ { "name": "sodium:proton antiporter activity", "id": "GO:0015385", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015385", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3U6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3U6" } ], "pmid": "" }, { "name": "monoatomic ion channel activity", "id": "GO:0005216", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005216", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3U6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3U6" } ], "pmid": "" }, { "name": "potassium:proton antiporter activity", "id": "GO:0015386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015386", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3U6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3U6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6G3U6-1", "start_pos": "869", "end_pos": "869", "site_lbl": "Thr869", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 869, "start_aa": "Thr", "end_pos": 869, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr869", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6G3U6-1" }, { "uniprot_canonical_ac": "A0A8I6AML0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AML0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AML0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 782, "chemical_mass": 86166.0, "gene_names": "Rnf43;RGD1305204;Rnf43", "protein_name": "E3 ubiquitin-protein ligase RNF43", "disease": [ { "disease_id": "DOID:0050869", "name": "villous adenoma", "description": "An adenoma that is located_in the colon and other places in the gastrointestinal tract and sometimes in other parts of the body.", "url": "https://disease-ontology.org/term/DOID:0050869", "evidence": [ { "id": "0050869", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050869" } ], "weight": 0.0 }, { "disease_id": "DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ], "weight": 0.0 }, { "disease_id": "DOID:1380", "name": "endometrial cancer", "description": "A uterine cancer that is located_in tissues lining the uterus.", "url": "https://disease-ontology.org/term/DOID:1380", "evidence": [ { "id": "1380", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1380" } ], "weight": 0.0 }, { "disease_id": "DOID:218", "name": "ascending colon cancer", "description": "", "url": "https://disease-ontology.org/term/DOID:218", "evidence": [ { "id": "218", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:218" } ], "weight": 0.0 }, { "disease_id": "DOID:219", "name": "colon cancer", "description": "A colorectal cancer that is located_in the colon.", "url": "https://disease-ontology.org/term/DOID:219", "evidence": [ { "id": "219", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:219" } ], "weight": 0.0 }, { "disease_id": "DOID:3070", "name": "high grade glioma", "description": "A cell type cancer that has_material_basis_in glial cells and is located in brain or located in spine.", "url": "https://disease-ontology.org/term/DOID:3070", "evidence": [ { "id": "3070", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3070" } ], "weight": 0.0 }, { "disease_id": "DOID:3717", "name": "gastric adenocarcinoma", "description": "A stomach carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:3717", "evidence": [ { "id": "3717", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3717" } ], "weight": 0.0 }, { "disease_id": "DOID:3910", "name": "lung adenocarcinoma", "description": "A lung non-small cell carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:3910", "evidence": [ { "id": "3910", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3910" } ], "weight": 0.0 }, { "disease_id": "DOID:4928", "name": "intrahepatic cholangiocarcinoma", "description": "A cholangiocarcinoma that arises from the intrahepatic bile duct epithelium in any site of the intrahepatic biliary tree.", "url": "https://disease-ontology.org/term/DOID:4928", "evidence": [ { "id": "4928", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4928" } ], "weight": 0.0 }, { "disease_id": "DOID:4947", "name": "cholangiocarcinoma", "description": "A bile duct adenocarcinoma that has_material_basis_in bile duct epithelial cells.", "url": "https://disease-ontology.org/term/DOID:4947", "evidence": [ { "id": "4947", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4947" } ], "weight": 0.0 }, { "disease_id": "DOID:5517", "name": "stomach carcinoma", "description": "A stomach cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:5517", "evidence": [ { "id": "5517", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5517" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 }, { "disease_id": "DOID:9778", "name": "irritable bowel syndrome", "description": "An intestinal disease that is characterized by chronic abdominal pain, discomfort, bloating, and alteration of bowel habits in the absence of any detectable organic cause.", "url": "https://disease-ontology.org/term/DOID:9778", "evidence": [ { "id": "9778", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9778" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AML0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AML0" } ], "pmid": "" }, { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AML0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AML0" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AML0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AML0" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AML0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AML0" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AML0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AML0" } ], "pmid": "" }, { "name": "frizzled binding", "id": "GO:0005109", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005109", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AML0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AML0" } ], "pmid": "" }, { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AML0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AML0" } ], "pmid": "" } ], "biological_process": [ { "name": "Wnt signaling pathway", "id": "GO:0016055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AML0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AML0" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AML0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AML0" } ], "pmid": "" }, { "name": "negative regulation of Wnt signaling pathway", "id": "GO:0030178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030178", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AML0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AML0" } ], "pmid": "" }, { "name": "stem cell proliferation", "id": "GO:0072089", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072089", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AML0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AML0" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AML0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AML0" } ], "pmid": "" }, { "name": "Wnt receptor catabolic process", "id": "GO:0038018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038018", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AML0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AML0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AML0-1" }, { "uniprot_canonical_ac": "A0A8I5ZSL2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZSL2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZSL2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 154, "chemical_mass": 16761.0, "gene_names": "Isca2;RGD1563216", "protein_name": "Iron-sulfur cluster assembly 2 homolog, mitochondrial", "disease": [ { "disease_id": "DOID:0080136", "name": "multiple mitochondrial dysfunctions syndrome 4", "description": "A multiple mitochondrial dysfunctions syndrome that is characterized by normal development for the first months of life, followed by progressive loss of motor and social skills with hypotonia, spasticity, and nystagmus, resulting in death in early childhood, and has_material_basis_in autosomal recessive inheritance of homozygous or compound heterozygous mutation in the iron-sulfur cluster assembly 2 gene on chromosome 14q24.", "url": "https://disease-ontology.org/term/DOID:0080136", "evidence": [ { "id": "0080136", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080136" } ], "weight": 0.0 } ], "biological_process": [ { "name": "iron-sulfur cluster assembly", "id": "GO:0016226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016226", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZSL2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZSL2" } ], "pmid": "" }, { "name": "protein maturation", "id": "GO:0051604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051604", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZSL2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZSL2" } ], "pmid": "" } ], "molecular_function": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZSL2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZSL2" } ], "pmid": "" }, { "name": "4 iron, 4 sulfur cluster binding", "id": "GO:0051539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051539", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZSL2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZSL2" } ], "pmid": "" }, { "name": "2 iron, 2 sulfur cluster binding", "id": "GO:0051537", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051537", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZSL2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZSL2" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZSL2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZSL2" } ], "pmid": "" }, { "name": "iron-sulfur cluster binding", "id": "GO:0051536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051536", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZSL2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZSL2" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZSL2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZSL2" } ], "pmid": "" }, { "name": "iron-sulfur cluster assembly complex", "id": "GO:1990229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990229", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZSL2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZSL2" } ], "pmid": "" }, { "name": "mitochondrial [4Fe-4S] assembly complex", "id": "GO:0120510", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120510", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZSL2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZSL2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZSL2-1" }, { "uniprot_canonical_ac": "A0A8I6AQC0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQC0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQC0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 680, "chemical_mass": 77144.0, "gene_names": "Cpsf3", "protein_name": "Cleavage and polyadenylation specificity factor subunit 3", "disease": [], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQC0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQC0" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQC0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQC0" } ], "pmid": "" }, { "name": "RNA endonuclease activity", "id": "GO:0004521", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004521", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQC0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQC0" } ], "pmid": "" }, { "name": "5'-3' RNA exonuclease activity", "id": "GO:0004534", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004534", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQC0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQC0" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQC0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQC0" } ], "pmid": "" }, { "name": "nuclease activity", "id": "GO:0004518", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004518", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQC0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQC0" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of G1/S transition of mitotic cell cycle", "id": "GO:1900087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900087", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQC0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQC0" } ], "pmid": "" }, { "name": "mRNA 3'-end processing by stem-loop binding and cleavage", "id": "GO:0006398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006398", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQC0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQC0" } ], "pmid": "" }, { "name": "mRNA 3'-end processing", "id": "GO:0031124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031124", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQC0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQC0" } ], "pmid": "" }, { "name": "co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway", "id": "GO:0180010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0180010", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQC0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQC0" } ], "pmid": "" }, { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQC0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQC0" } ], "pmid": "" } ], "cellular_component": [ { "name": "mRNA cleavage and polyadenylation specificity factor complex", "id": "GO:0005847", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005847", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQC0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQC0" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQC0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQC0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AQC0-1" }, { "uniprot_canonical_ac": "A0A8I6AHT4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHT4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHT4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1281, "chemical_mass": 138240.0, "gene_names": "Camsap3;Camsap3;RGD1307246", "protein_name": "", "disease": [], "molecular_function": [ { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHT4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHT4" } ], "pmid": "" }, { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHT4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHT4" } ], "pmid": "" }, { "name": "spectrin binding", "id": "GO:0030507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030507", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHT4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHT4" } ], "pmid": "" }, { "name": "microtubule minus-end binding", "id": "GO:0051011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051011", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHT4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHT4" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHT4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHT4" } ], "pmid": "" } ], "cellular_component": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHT4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHT4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHT4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHT4" } ], "pmid": "" }, { "name": "zonula adherens", "id": "GO:0005915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005915", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHT4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHT4" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHT4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHT4" } ], "pmid": "" }, { "name": "motile cilium", "id": "GO:0031514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031514", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHT4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHT4" } ], "pmid": "" }, { "name": "microtubule cytoskeleton", "id": "GO:0015630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015630", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHT4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHT4" } ], "pmid": "" }, { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHT4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHT4" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHT4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHT4" } ], "pmid": "" }, { "name": "microtubule minus-end", "id": "GO:0036449", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036449", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHT4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHT4" } ], "pmid": "" } ], "biological_process": [ { "name": "neuron projection development", "id": "GO:0031175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031175", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHT4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHT4" } ], "pmid": "" }, { "name": "microtubule anchoring", "id": "GO:0034453", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034453", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHT4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHT4" } ], "pmid": "" }, { "name": "regulation of microtubule cytoskeleton organization", "id": "GO:0070507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070507", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHT4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHT4" } ], "pmid": "" }, { "name": "zonula adherens maintenance", "id": "GO:0045218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045218", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHT4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHT4" } ], "pmid": "" }, { "name": "epithelial cell-cell adhesion", "id": "GO:0090136", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090136", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHT4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHT4" } ], "pmid": "" }, { "name": "regulation of focal adhesion assembly", "id": "GO:0051893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051893", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHT4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHT4" } ], "pmid": "" }, { "name": "embryo development ending in birth or egg hatching", "id": "GO:0009792", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009792", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHT4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHT4" } ], "pmid": "" }, { "name": "protein transport along microtubule", "id": "GO:0098840", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098840", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHT4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHT4" } ], "pmid": "" }, { "name": "in utero embryonic development", "id": "GO:0001701", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001701", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHT4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHT4" } ], "pmid": "" }, { "name": "establishment of epithelial cell apical/basal polarity", "id": "GO:0045198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045198", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHT4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHT4" } ], "pmid": "" }, { "name": "regulation of microtubule polymerization", "id": "GO:0031113", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031113", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHT4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHT4" } ], "pmid": "" }, { "name": "regulation of cell migration", "id": "GO:0030334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030334", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHT4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHT4" } ], "pmid": "" }, { "name": "negative regulation of microtubule depolymerization", "id": "GO:0007026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007026", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHT4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHT4" } ], "pmid": "" }, { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHT4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHT4" } ], "pmid": "" }, { "name": "cilium movement", "id": "GO:0003341", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003341", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHT4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHT4" } ], "pmid": "" }, { "name": "cytoplasmic microtubule organization", "id": "GO:0031122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031122", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHT4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHT4" } ], "pmid": "" }, { "name": "establishment or maintenance of microtubule cytoskeleton polarity", "id": "GO:0030951", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030951", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHT4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHT4" } ], "pmid": "" }, { "name": "regulation of Golgi organization", "id": "GO:1903358", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903358", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHT4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHT4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6AHT4-1", "start_pos": "1226", "end_pos": "1226", "site_lbl": "Thr1226", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1226, "start_aa": "Thr", "end_pos": 1226, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1226", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I6AHT4-1", "start_pos": "804", "end_pos": "804", "site_lbl": "Thr804", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 804, "start_aa": "Thr", "end_pos": 804, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr804", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6AHT4-1" }, { "uniprot_canonical_ac": "A0A8I6GI31-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI31", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI31" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 295, "chemical_mass": 32138.0, "gene_names": "Ercc1", "protein_name": "DNA excision repair protein ERCC-1", "disease": [ { "disease_id": "DOID:0060590", "name": "XFE progeroid syndrome", "description": "A progeroid syndrome that is characterized by aged bird-like facies, lack of subcutaneous fat, dwarfism, cachexia and microcephaly and that has_material_basis_in homozygous mutation in the ERCC4 gene on chromosome 16p13.", "url": "https://disease-ontology.org/term/DOID:0060590", "evidence": [ { "id": "0060590", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060590" } ], "weight": 0.0 }, { "disease_id": "DOID:0080914", "name": "cerebrooculofacioskeletal syndrome 4", "description": "A cerebrooculofacioskeletal syndrome that has_material_basis_in homozygous or compound heterozygous mutation in the ERCC1 gene on chromosome 19q13.", "url": "https://disease-ontology.org/term/DOID:0080914", "evidence": [ { "id": "0080914", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080914" } ], "weight": 0.0 }, { "disease_id": "DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ], "weight": 0.0 }, { "disease_id": "DOID:1074", "name": "kidney failure", "description": "A kidney disease characterized by the failure of the kidneys to adequately filter waste products from the blood.", "url": "https://disease-ontology.org/term/DOID:1074", "evidence": [ { "id": "1074", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1074" } ], "weight": 0.0 }, { "disease_id": "DOID:14227", "name": "azoospermia", "description": "A male infertility disease characterized by the absence of any measurable level of sperm in semen.", "url": "https://disease-ontology.org/term/DOID:14227", "evidence": [ { "id": "14227", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14227" } ], "weight": 0.0 }, { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:1793", "name": "pancreatic cancer", "description": "An endocrine gland cancer located_in the pancreas.", "url": "https://disease-ontology.org/term/DOID:1793", "evidence": [ { "id": "1793", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1793" } ], "weight": 0.0 }, { "disease_id": "DOID:2152", "name": "ovary epithelial cancer", "description": "An ovarian cancer that is derives_from ovarian surface epithelium.", "url": "https://disease-ontology.org/term/DOID:2152", "evidence": [ { "id": "2152", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2152" } ], "weight": 0.0 }, { "disease_id": "DOID:224", "name": "transient cerebral ischemia", "description": "A brain ischemia that is characterized by ischemia of brief duration and without resultant tissue death.", "url": "https://disease-ontology.org/term/DOID:224", "evidence": [ { "id": "224", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:224" } ], "weight": 0.0 }, { "disease_id": "DOID:2355", "name": "anemia", "description": "A hematopoietic system disease that is characterized by a decrease in the normal number of red blood cells.", "url": "https://disease-ontology.org/term/DOID:2355", "evidence": [ { "id": "2355", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2355" } ], "weight": 0.0 }, { "disease_id": "DOID:2394", "name": "ovarian cancer", "description": "A female reproductive organ cancer that is located_in the ovary.", "url": "https://disease-ontology.org/term/DOID:2394", "evidence": [ { "id": "2394", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2394" } ], "weight": 0.0 }, { "disease_id": "DOID:3070", "name": "high grade glioma", "description": "A cell type cancer that has_material_basis_in glial cells and is located in brain or located in spine.", "url": "https://disease-ontology.org/term/DOID:3070", "evidence": [ { "id": "3070", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3070" } ], "weight": 0.0 }, { "disease_id": "DOID:3347", "name": "osteosarcoma", "description": "A bone sarcoma that is located_in bone that has_material_basis_in cells of mesenchymal origin. It usually involves bones and less frequently extraosseous sites. It often involves the long bones (particularly distal femur, proximal tibia, and proximal humerus).", "url": "https://disease-ontology.org/term/DOID:3347", "evidence": [ { "id": "3347", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3347" } ], "weight": 0.0 }, { "disease_id": "DOID:3748", "name": "esophagus squamous cell carcinoma", "description": "An esophageal carcinoma that derives_from epithelial squamous cells located_in the esophagus.", "url": "https://disease-ontology.org/term/DOID:3748", "evidence": [ { "id": "3748", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3748" } ], "weight": 0.0 }, { "disease_id": "DOID:3905", "name": "lung carcinoma", "description": "A lung cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells and is located_in the lungs and has_symptom cough and has_symptom chest discomfort or pain and has_symptom weight loss and has_symptom hemoptysis.", "url": "https://disease-ontology.org/term/DOID:3905", "evidence": [ { "id": "3905", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3905" } ], "weight": 0.0 }, { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 }, { "disease_id": "DOID:4914", "name": "esophagus adenocarcinoma", "description": "An esophageal carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:4914", "evidence": [ { "id": "4914", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4914" } ], "weight": 0.0 }, { "disease_id": "DOID:4971", "name": "myelofibrosis", "description": "A myeloid neoplasm that is located in the bone marrow which results in bone marrow being replaced by fibrous (scar) tissue.", "url": "https://disease-ontology.org/term/DOID:4971", "evidence": [ { "id": "4971", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4971" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:9119", "name": "acute myeloid leukemia", "description": "A myeloid leukemia that is characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal blood cells.", "url": "https://disease-ontology.org/term/DOID:9119", "evidence": [ { "id": "9119", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9119" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 }, { "disease_id": "DOID:9538", "name": "multiple myeloma", "description": "A myeloid neoplasm that is located_in the plasma cells in bone marrow.", "url": "https://disease-ontology.org/term/DOID:9538", "evidence": [ { "id": "9538", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9538" } ], "weight": 0.0 }, { "disease_id": "DOID:9952", "name": "acute lymphoblastic leukemia", "description": "A acute leukemia that is characterized by over production of lymphoblasts.", "url": "https://disease-ontology.org/term/DOID:9952", "evidence": [ { "id": "9952", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9952" } ], "weight": 0.0 } ], "biological_process": [ { "name": "mitotic recombination", "id": "GO:0006312", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006312", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI31", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI31" } ], "pmid": "" }, { "name": "double-strand break repair", "id": "GO:0006302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006302", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI31", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI31" } ], "pmid": "" }, { "name": "UV-damage excision repair", "id": "GO:0070914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070914", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI31", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI31" } ], "pmid": "" }, { "name": "DNA recombination", "id": "GO:0006310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006310", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI31", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI31" } ], "pmid": "" }, { "name": "regulation of telomere maintenance", "id": "GO:0032204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032204", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI31", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI31" } ], "pmid": "" }, { "name": "telomere maintenance", "id": "GO:0000723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000723", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI31", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI31" } ], "pmid": "" }, { "name": "nucleotide-excision repair", "id": "GO:0006289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006289", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI31", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI31" } ], "pmid": "" }, { "name": "positive regulation of transcription initiation by RNA polymerase II", "id": "GO:0060261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060261", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI31", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI31" } ], "pmid": "" }, { "name": "pyrimidine dimer repair by nucleotide-excision repair", "id": "GO:0000720", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000720", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI31", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI31" } ], "pmid": "" }, { "name": "syncytium formation", "id": "GO:0006949", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006949", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI31", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI31" } ], "pmid": "" }, { "name": "negative regulation of telomere maintenance", "id": "GO:0032205", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032205", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI31", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI31" } ], "pmid": "" }, { "name": "telomeric DNA-containing double minutes formation", "id": "GO:0061819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061819", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI31", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI31" } ], "pmid": "" }, { "name": "positive regulation of t-circle formation", "id": "GO:1904431", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904431", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI31", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI31" } ], "pmid": "" }, { "name": "negative regulation of protection from non-homologous end joining at telomere", "id": "GO:1905765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905765", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI31", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI31" } ], "pmid": "" }, { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI31", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI31" } ], "pmid": "" }, { "name": "response to oxidative stress", "id": "GO:0006979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006979", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI31", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI31" } ], "pmid": "" }, { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI31", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI31" } ], "pmid": "" }, { "name": "response to nutrient", "id": "GO:0007584", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007584", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI31", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI31" } ], "pmid": "" }, { "name": "cell population proliferation", "id": "GO:0008283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008283", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI31", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI31" } ], "pmid": "" }, { "name": "multicellular organism growth", "id": "GO:0035264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035264", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI31", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI31" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI31", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI31" } ], "pmid": "" }, { "name": "male gonad development", "id": "GO:0008584", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008584", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI31", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI31" } ], "pmid": "" }, { "name": "response to cadmium ion", "id": "GO:0046686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046686", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI31", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI31" } ], "pmid": "" }, { "name": "double-strand break repair via nonhomologous end joining", "id": "GO:0006303", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006303", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI31", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI31" } ], "pmid": "" }, { "name": "germ cell development", "id": "GO:0007281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007281", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI31", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI31" } ], "pmid": "" }, { "name": "response to sucrose", "id": "GO:0009744", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009744", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI31", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI31" } ], "pmid": "" }, { "name": "insulin-like growth factor receptor signaling pathway", "id": "GO:0048009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048009", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI31", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI31" } ], "pmid": "" }, { "name": "isotype switching", "id": "GO:0045190", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045190", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI31", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI31" } ], "pmid": "" }, { "name": "response to X-ray", "id": "GO:0010165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010165", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI31", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI31" } ], "pmid": "" }, { "name": "response to immobilization stress", "id": "GO:0035902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035902", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI31", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI31" } ], "pmid": "" }, { "name": "cell development", "id": "GO:0048468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048468", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI31", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI31" } ], "pmid": "" }, { "name": "embryonic organ development", "id": "GO:0048568", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048568", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI31", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI31" } ], "pmid": "" }, { "name": "oogenesis", "id": "GO:0048477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048477", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI31", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI31" } ], "pmid": "" }, { "name": "interstrand cross-link repair", "id": "GO:0036297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036297", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI31", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI31" } ], "pmid": "" }, { "name": "t-circle formation", "id": "GO:0090656", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090656", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI31", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI31" } ], "pmid": "" }, { "name": "determination of adult lifespan", "id": "GO:0008340", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008340", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI31", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI31" } ], "pmid": "" }, { "name": "replicative senescence", "id": "GO:0090399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090399", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI31", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI31" } ], "pmid": "" }, { "name": "UV protection", "id": "GO:0009650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009650", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI31", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI31" } ], "pmid": "" }, { "name": "chromosome organization", "id": "GO:0051276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051276", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI31", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI31" } ], "pmid": "" }, { "name": "post-embryonic hemopoiesis", "id": "GO:0035166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035166", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI31", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI31" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleotide-excision repair factor 1 complex", "id": "GO:0000110", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000110", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI31", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI31" } ], "pmid": "" }, { "name": "ERCC4-ERCC1 complex", "id": "GO:0070522", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070522", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI31", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI31" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI31", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI31" } ], "pmid": "" }, { "name": "nucleotide-excision repair complex", "id": "GO:0000109", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000109", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI31", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI31" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI31", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI31" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI31", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI31" } ], "pmid": "" } ], "molecular_function": [ { "name": "damaged DNA binding", "id": "GO:0003684", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003684", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI31", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI31" } ], "pmid": "" }, { "name": "single-stranded DNA binding", "id": "GO:0003697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003697", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI31", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI31" } ], "pmid": "" }, { "name": "TFIID-class transcription factor complex binding", "id": "GO:0001094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001094", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI31", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI31" } ], "pmid": "" }, { "name": "promoter-specific chromatin binding", "id": "GO:1990841", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990841", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI31", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI31" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6GI31-1", "start_pos": "24", "end_pos": "24", "site_lbl": "Thr24", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 24, "start_aa": "Thr", "end_pos": 24, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr24", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I6GI31-1", "start_pos": "46", "end_pos": "46", "site_lbl": "Thr46", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 46, "start_aa": "Thr", "end_pos": 46, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr46", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6GI31-1" }, { "uniprot_canonical_ac": "A0A8I6GB45-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GB45", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GB45" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 685, "chemical_mass": 76578.0, "gene_names": "Misp;LOC500797", "protein_name": "", "disease": [], "cellular_component": [ { "name": "actin filament", "id": "GO:0005884", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005884", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GB45", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GB45" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GB45", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GB45" } ], "pmid": "" }, { "name": "focal adhesion", "id": "GO:0005925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005925", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GB45", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GB45" } ], "pmid": "" }, { "name": "cortical actin cytoskeleton", "id": "GO:0030864", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030864", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GB45", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GB45" } ], "pmid": "" }, { "name": "spindle pole centrosome", "id": "GO:0031616", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031616", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GB45", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GB45" } ], "pmid": "" }, { "name": "mitotic spindle astral microtubule end", "id": "GO:1905721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905721", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GB45", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GB45" } ], "pmid": "" } ], "biological_process": [ { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GB45", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GB45" } ], "pmid": "" }, { "name": "mitotic spindle assembly", "id": "GO:0090307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090307", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GB45", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GB45" } ], "pmid": "" }, { "name": "cortical actin cytoskeleton organization", "id": "GO:0030866", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030866", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GB45", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GB45" } ], "pmid": "" }, { "name": "establishment of mitotic spindle orientation", "id": "GO:0000132", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000132", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GB45", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GB45" } ], "pmid": "" }, { "name": "astral microtubule organization", "id": "GO:0030953", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030953", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GB45", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GB45" } ], "pmid": "" }, { "name": "establishment of centrosome localization", "id": "GO:0051660", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051660", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GB45", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GB45" } ], "pmid": "" } ], "molecular_function": [ { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GB45", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GB45" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6GB45-1" }, { "uniprot_canonical_ac": "A0A8I6AGZ6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AGZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AGZ6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 617, "chemical_mass": 70622.0, "gene_names": "Fam161b", "protein_name": "", "disease": [], "cellular_component": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AGZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AGZ6" } ], "pmid": "" }, { "name": "microtubule cytoskeleton", "id": "GO:0015630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015630", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AGZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AGZ6" } ], "pmid": "" }, { "name": "cytoplasmic microtubule", "id": "GO:0005881", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005881", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AGZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AGZ6" } ], "pmid": "" } ], "biological_process": [ { "name": "cilium organization", "id": "GO:0044782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044782", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AGZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AGZ6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AGZ6-1" }, { "uniprot_canonical_ac": "A0A8I6AN25-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AN25", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AN25" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 795, "chemical_mass": 87899.0, "gene_names": "Cnksr1;Cnksr1", "protein_name": "", "disease": [], "biological_process": [ { "name": "synapse organization", "id": "GO:0050808", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050808", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AN25", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AN25" } ], "pmid": "" } ], "cellular_component": [ { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AN25", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AN25" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AN25", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AN25" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6AN25-1", "start_pos": "429", "end_pos": "429", "site_lbl": "Thr429", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 429, "start_aa": "Thr", "end_pos": 429, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr429", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I6AN25-1", "start_pos": "431", "end_pos": "431", "site_lbl": "Thr431", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 431, "start_aa": "Thr", "end_pos": 431, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr431", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6AN25-1" }, { "uniprot_canonical_ac": "A0A8I6G3R2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3R2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3R2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 914, "chemical_mass": 100691.0, "gene_names": "Cbl;Cbl;RGD1561386;c-Cbl", "protein_name": "E3 ubiquitin-protein ligase CBL", "disease": [ { "disease_id": "DOID:0050458", "name": "juvenile myelomonocytic leukemia", "description": "A myelodysplastic/myeloproliferative neoplasm that is characterized by the uncontrolled growth of monocytes.", "url": "https://disease-ontology.org/term/DOID:0050458", "evidence": [ { "id": "0050458", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050458" } ], "weight": 0.0 }, { "disease_id": "DOID:0070004", "name": "myeloid neoplasm", "description": "A bone marrow cancer that is formed of any one of the bone marrow cells belonging to the granulocytic (neutrophil, eosinophil, basophil), monocytic/macrophage, erythroid, megakaryocytic and mast cell lineages.", "url": "https://disease-ontology.org/term/DOID:0070004", "evidence": [ { "id": "0070004", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070004" } ], "weight": 0.0 }, { "disease_id": "DOID:2226", "name": "myeloproliferative neoplasm", "description": "A myeloid neoplasm that is characterized by a group of slow growing blood cancers in which large numbers of abnormal red blood cells, white blood cells, or platelets grow and spread in the bone marrow and the peripheral blood.", "url": "https://disease-ontology.org/term/DOID:2226", "evidence": [ { "id": "2226", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2226" } ], "weight": 0.0 }, { "disease_id": "DOID:224", "name": "transient cerebral ischemia", "description": "A brain ischemia that is characterized by ischemia of brief duration and without resultant tissue death.", "url": "https://disease-ontology.org/term/DOID:224", "evidence": [ { "id": "224", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:224" } ], "weight": 0.0 }, { "disease_id": "DOID:3347", "name": "osteosarcoma", "description": "A bone sarcoma that is located_in bone that has_material_basis_in cells of mesenchymal origin. It usually involves bones and less frequently extraosseous sites. It often involves the long bones (particularly distal femur, proximal tibia, and proximal humerus).", "url": "https://disease-ontology.org/term/DOID:3347", "evidence": [ { "id": "3347", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3347" } ], "weight": 0.0 }, { "disease_id": "DOID:3490", "name": "Noonan syndrome", "description": "A RASopathy that is characterized by mildly unusual facial features, short stature, heart defects, bleeding problems, skeletal malformations, and many other signs and symptoms.", "url": "https://disease-ontology.org/term/DOID:3490", "evidence": [ { "id": "3490", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3490" } ], "weight": 0.0 }, { "disease_id": "DOID:3827", "name": "congenital diaphragmatic hernia", "description": "A diaphragm disease characterized by the lack of development of all or part of the diaphragm, which results in an abnormal opening that allows the stomach and intestines to move into the chest cavity and crowd the heart and lungs.", "url": "https://disease-ontology.org/term/DOID:3827", "evidence": [ { "id": "3827", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3827" } ], "weight": 0.0 }, { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 }, { "disease_id": "DOID:4195", "name": "hyperglycemia", "description": "", "url": "https://disease-ontology.org/term/DOID:4195", "evidence": [ { "id": "4195", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4195" } ], "weight": 0.0 }, { "disease_id": "DOID:6000", "name": "congestive heart failure", "description": "A heart disease that is characterized by any structural or functional cardiac disorder that impairs the ability of the heart to fill with or pump a sufficient amount of blood throughout the body.", "url": "https://disease-ontology.org/term/DOID:6000", "evidence": [ { "id": "6000", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6000" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:9119", "name": "acute myeloid leukemia", "description": "A myeloid leukemia that is characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal blood cells.", "url": "https://disease-ontology.org/term/DOID:9119", "evidence": [ { "id": "9119", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9119" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 }, { "disease_id": "DOID:9538", "name": "multiple myeloma", "description": "A myeloid neoplasm that is located_in the plasma cells in bone marrow.", "url": "https://disease-ontology.org/term/DOID:9538", "evidence": [ { "id": "9538", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9538" } ], "weight": 0.0 }, { "disease_id": "DOID:9744", "name": "type 1 diabetes mellitus", "description": "A diabetes mellitus that is characterized by destruction of pancreatic beta cells resulting in absent or extremely low insulin production.", "url": "https://disease-ontology.org/term/DOID:9744", "evidence": [ { "id": "9744", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9744" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "phosphotyrosine residue binding", "id": "GO:0001784", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001784", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3R2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3R2" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3R2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3R2" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3R2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3R2" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3R2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3R2" } ], "pmid": "" }, { "name": "SH3 domain binding", "id": "GO:0017124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017124", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3R2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3R2" } ], "pmid": "" }, { "name": "ephrin receptor binding", "id": "GO:0046875", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046875", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3R2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3R2" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3R2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3R2" } ], "pmid": "" }, { "name": "receptor tyrosine kinase binding", "id": "GO:0030971", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030971", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3R2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3R2" } ], "pmid": "" }, { "name": "phosphatidylinositol 3-kinase regulatory subunit binding", "id": "GO:0036312", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036312", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3R2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3R2" } ], "pmid": "" }, { "name": "protein tyrosine kinase binding", "id": "GO:1990782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990782", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3R2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3R2" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3R2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3R2" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3R2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3R2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3R2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3R2" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3R2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3R2" } ], "pmid": "" }, { "name": "focal adhesion", "id": "GO:0005925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005925", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3R2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3R2" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3R2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3R2" } ], "pmid": "" }, { "name": "growth cone", "id": "GO:0030426", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030426", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3R2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3R2" } ], "pmid": "" }, { "name": "membrane raft", "id": "GO:0045121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045121", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3R2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3R2" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3R2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3R2" } ], "pmid": "" }, { "name": "flotillin complex", "id": "GO:0016600", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016600", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3R2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3R2" } ], "pmid": "" } ], "biological_process": [ { "name": "cell surface receptor signaling pathway", "id": "GO:0007166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007166", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3R2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3R2" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3R2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3R2" } ], "pmid": "" }, { "name": "regulation of signaling", "id": "GO:0023051", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0023051", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3R2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3R2" } ], "pmid": "" }, { "name": "regulation of intracellular signal transduction", "id": "GO:1902531", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902531", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3R2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3R2" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3R2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3R2" } ], "pmid": "" }, { "name": "negative regulation of epidermal growth factor receptor signaling pathway", "id": "GO:0042059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042059", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3R2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3R2" } ], "pmid": "" }, { "name": "regulation of Rap protein signal transduction", "id": "GO:0032487", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032487", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3R2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3R2" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3R2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3R2" } ], "pmid": "" }, { "name": "response to gamma radiation", "id": "GO:0010332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010332", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3R2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3R2" } ], "pmid": "" }, { "name": "response to starvation", "id": "GO:0042594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042594", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3R2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3R2" } ], "pmid": "" }, { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3R2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3R2" } ], "pmid": "" }, { "name": "response to ethanol", "id": "GO:0045471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045471", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3R2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3R2" } ], "pmid": "" }, { "name": "positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction", "id": "GO:0051897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051897", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3R2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3R2" } ], "pmid": "" }, { "name": "cellular response to nerve growth factor stimulus", "id": "GO:1990090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990090", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3R2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3R2" } ], "pmid": "" }, { "name": "cellular response to hypoxia", "id": "GO:0071456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071456", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3R2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3R2" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3R2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3R2" } ], "pmid": "" }, { "name": "male gonad development", "id": "GO:0008584", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008584", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3R2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3R2" } ], "pmid": "" }, { "name": "protein stabilization", "id": "GO:0050821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050821", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3R2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3R2" } ], "pmid": "" }, { "name": "response to activity", "id": "GO:0014823", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014823", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3R2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3R2" } ], "pmid": "" }, { "name": "positive regulation of receptor-mediated endocytosis", "id": "GO:0048260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048260", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3R2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3R2" } ], "pmid": "" }, { "name": "protein polyubiquitination", "id": "GO:0000209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000209", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3R2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3R2" } ], "pmid": "" }, { "name": "protein autoubiquitination", "id": "GO:0051865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051865", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3R2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3R2" } ], "pmid": "" }, { "name": "cellular response to platelet-derived growth factor stimulus", "id": "GO:0036120", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036120", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3R2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3R2" } ], "pmid": "" }, { "name": "protein K63-linked ubiquitination", "id": "GO:0070534", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070534", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3R2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3R2" } ], "pmid": "" }, { "name": "negative regulation of T cell receptor signaling pathway", "id": "GO:0050860", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050860", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3R2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3R2" } ], "pmid": "" }, { "name": "negative regulation of T cell activation", "id": "GO:0050868", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050868", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3R2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3R2" } ], "pmid": "" }, { "name": "response to testosterone", "id": "GO:0033574", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033574", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3R2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3R2" } ], "pmid": "" }, { "name": "protein monoubiquitination", "id": "GO:0006513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006513", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3R2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3R2" } ], "pmid": "" }, { "name": "mast cell degranulation", "id": "GO:0043303", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043303", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3R2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3R2" } ], "pmid": "" }, { "name": "ubiquitin-dependent endocytosis", "id": "GO:0070086", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070086", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3R2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3R2" } ], "pmid": "" }, { "name": "regulation of platelet-derived growth factor receptor-alpha signaling pathway", "id": "GO:2000583", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000583", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3R2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3R2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6G3R2-1" }, { "uniprot_canonical_ac": "A0A8I6AS15-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AS15", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AS15" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 586, "chemical_mass": 64181.0, "gene_names": "Ikzf4;Ikzf4", "protein_name": "", "disease": [ { "disease_id": "DOID:640", "name": "encephalomyelitis", "description": "", "url": "https://disease-ontology.org/term/DOID:640", "evidence": [ { "id": "640", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:640" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AS15", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AS15" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AS15", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AS15" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AS15", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AS15" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AS15", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AS15" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AS15", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AS15" } ], "pmid": "" }, { "name": "protein domain specific binding", "id": "GO:0019904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019904", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AS15", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AS15" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AS15", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AS15" } ], "pmid": "" }, { "name": "bHLH transcription factor binding", "id": "GO:0043425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043425", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AS15", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AS15" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AS15", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AS15" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AS15", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AS15" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AS15", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AS15" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AS15", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AS15" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AS15", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AS15" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AS15", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AS15" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AS15", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AS15" } ], "pmid": "" }, { "name": "protein homooligomerization", "id": "GO:0051260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051260", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AS15", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AS15" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AS15", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AS15" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6AS15-1", "start_pos": "243", "end_pos": "243", "site_lbl": "Thr243", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 243, "start_aa": "Thr", "end_pos": 243, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr243", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6AS15-1" }, { "uniprot_canonical_ac": "A0A8I6GLR7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GLR7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GLR7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 4069, "chemical_mass": 465510.0, "gene_names": "Dnah3;AABR07005597.1;Dnah3;Dnahc3l;Dnahc3", "protein_name": "Dynein axonemal heavy chain 3", "disease": [], "biological_process": [ { "name": "microtubule-based movement", "id": "GO:0007018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007018", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GLR7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GLR7" } ], "pmid": "" }, { "name": "sperm axoneme assembly", "id": "GO:0007288", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007288", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GLR7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GLR7" } ], "pmid": "" }, { "name": "inner dynein arm assembly", "id": "GO:0036159", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036159", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GLR7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GLR7" } ], "pmid": "" } ], "cellular_component": [ { "name": "dynein complex", "id": "GO:0030286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030286", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GLR7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GLR7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GLR7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GLR7" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GLR7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GLR7" } ], "pmid": "" }, { "name": "sperm flagellum", "id": "GO:0036126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036126", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GLR7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GLR7" } ], "pmid": "" }, { "name": "axonemal dynein complex", "id": "GO:0005858", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005858", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GLR7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GLR7" } ], "pmid": "" } ], "molecular_function": [ { "name": "dynein light intermediate chain binding", "id": "GO:0051959", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051959", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GLR7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GLR7" } ], "pmid": "" }, { "name": "dynein intermediate chain binding", "id": "GO:0045505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045505", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GLR7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GLR7" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GLR7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GLR7" } ], "pmid": "" }, { "name": "minus-end-directed microtubule motor activity", "id": "GO:0008569", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008569", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GLR7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GLR7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6GLR7-1", "start_pos": "2029", "end_pos": "2029", "site_lbl": "Thr2029", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2029, "start_aa": "Thr", "end_pos": 2029, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2029", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I6GLR7-1", "start_pos": "2218", "end_pos": "2218", "site_lbl": "Thr2218", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2218, "start_aa": "Thr", "end_pos": 2218, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2218", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I6GLR7-1", "start_pos": "2603", "end_pos": "2603", "site_lbl": "Thr2603", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2603, "start_aa": "Thr", "end_pos": 2603, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2603", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6GLR7-1" }, { "uniprot_canonical_ac": "A0A8I5ZTL5-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTL5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTL5" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 295, "chemical_mass": 31891.0, "gene_names": "Tgif1", "protein_name": "", "disease": [ { "disease_id": "DOID:0110880", "name": "holoprosencephaly 4", "description": "A holoprosencephaly that has_material_basis_in heterozygous mutation in the TGIF gene on chromosome 18p11.", "url": "https://disease-ontology.org/term/DOID:0110880", "evidence": [ { "id": "0110880", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110880" } ], "weight": 0.0 }, { "disease_id": "DOID:10754", "name": "otitis media", "description": "A otitis which involves inflammation of the middle ear.", "url": "https://disease-ontology.org/term/DOID:10754", "evidence": [ { "id": "10754", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10754" } ], "weight": 0.0 }, { "disease_id": "DOID:4621", "name": "holoprosencephaly", "description": "A congenital nervous system abnormality characterized by failed or incomplete separation of the forebrain early in gestation; it is accompanied by a spectrum of characteristic craniofacial anomalies.", "url": "https://disease-ontology.org/term/DOID:4621", "evidence": [ { "id": "4621", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4621" } ], "weight": 0.0 }, { "disease_id": "DOID:767", "name": "muscular atrophy", "description": "", "url": "https://disease-ontology.org/term/DOID:767", "evidence": [ { "id": "767", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:767" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTL5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTL5" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTL5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTL5" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTL5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTL5" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTL5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTL5" } ], "pmid": "" }, { "name": "co-SMAD binding", "id": "GO:0070410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070410", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTL5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTL5" } ], "pmid": "" }, { "name": "sequence-specific double-stranded DNA binding", "id": "GO:1990837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990837", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTL5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTL5" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTL5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTL5" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTL5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTL5" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTL5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTL5" } ], "pmid": "" }, { "name": "regulation of gastrulation", "id": "GO:0010470", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010470", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTL5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTL5" } ], "pmid": "" }, { "name": "positive regulation of amacrine cell differentiation", "id": "GO:1902871", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902871", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTL5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTL5" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTL5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTL5" } ], "pmid": "" }, { "name": "nodal signaling pathway", "id": "GO:0038092", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038092", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTL5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTL5" } ], "pmid": "" }, { "name": "amacrine cell differentiation", "id": "GO:0035881", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035881", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTL5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTL5" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTL5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTL5" } ], "pmid": "" }, { "name": "negative regulation of cell population proliferation", "id": "GO:0008285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008285", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTL5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTL5" } ], "pmid": "" }, { "name": "negative regulation of gene expression", "id": "GO:0010629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010629", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTL5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTL5" } ], "pmid": "" }, { "name": "positive regulation of neuron differentiation", "id": "GO:0045666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045666", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTL5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTL5" } ], "pmid": "" }, { "name": "retina development in camera-type eye", "id": "GO:0060041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060041", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTL5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTL5" } ], "pmid": "" }, { "name": "cellular response to growth factor stimulus", "id": "GO:0071363", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071363", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTL5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTL5" } ], "pmid": "" }, { "name": "neural tube closure", "id": "GO:0001843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001843", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTL5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTL5" } ], "pmid": "" }, { "name": "determination of left/right symmetry", "id": "GO:0007368", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007368", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTL5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTL5" } ], "pmid": "" }, { "name": "positive regulation of fibroblast proliferation", "id": "GO:0048146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048146", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTL5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTL5" } ], "pmid": "" }, { "name": "dorsal/ventral pattern formation", "id": "GO:0009953", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009953", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTL5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTL5" } ], "pmid": "" }, { "name": "response to xenobiotic stimulus", "id": "GO:0009410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009410", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTL5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTL5" } ], "pmid": "" }, { "name": "negative regulation of retinoic acid receptor signaling pathway", "id": "GO:0048387", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048387", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTL5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTL5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I5ZTL5-1", "start_pos": "262", "end_pos": "262", "site_lbl": "Thr262", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 262, "start_aa": "Thr", "end_pos": 262, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr262", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I5ZTL5-1" }, { "uniprot_canonical_ac": "A0A8I6ARV9-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ARV9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ARV9" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 493, "chemical_mass": 55690.0, "gene_names": "Ctsa", "protein_name": "Carboxypeptidase", "disease": [ { "disease_id": "DOID:0061236", "name": "brain small vessel disease 6 with leukoencephalopathy", "description": "A brain small vessel disease characterized by central nervous system manifestations, including migraine, stroke, transient movement disorders, gait disturbance, and progressive cognitive decline that has_material_basis_in heterozygous mutation in the CTSA gene on chromosome 20q13.", "url": "https://disease-ontology.org/term/DOID:0061236", "evidence": [ { "id": "0061236", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061236" } ], "weight": 0.0 }, { "disease_id": "DOID:0080540", "name": "galactosialidosis", "description": "A lysosomal storage disease that is characterized by combined deficiency of beta-galactosidase and neuraminidase that has_material_basis_in homozygous or compound heterozygous mutation in the CTSA gene on chromosome 20q13.", "url": "https://disease-ontology.org/term/DOID:0080540", "evidence": [ { "id": "0080540", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080540" } ], "weight": 0.0 }, { "disease_id": "DOID:3211", "name": "lysosomal storage disease", "description": "An inherited metabolic disorder that involve an abnormal accumulation of substances inside the lysosome resulting from defects in lysosomal function.", "url": "https://disease-ontology.org/term/DOID:3211", "evidence": [ { "id": "3211", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3211" } ], "weight": 0.0 } ], "biological_process": [ { "name": "negative regulation of chaperone-mediated autophagy", "id": "GO:1904715", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904715", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ARV9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ARV9" } ], "pmid": "" }, { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ARV9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ARV9" } ], "pmid": "" }, { "name": "regulation of protein stability", "id": "GO:0031647", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031647", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ARV9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ARV9" } ], "pmid": "" } ], "molecular_function": [ { "name": "serine-type carboxypeptidase activity", "id": "GO:0004185", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004185", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ARV9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ARV9" } ], "pmid": "" } ], "cellular_component": [ { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ARV9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ARV9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6ARV9-1" }, { "uniprot_canonical_ac": "M0R957-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "M0R957", "url": "https://www.uniprot.org/uniprotkb/M0R957" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 200, "chemical_mass": 22091.0, "gene_names": "Ccdc28b;Ccdc28b", "protein_name": "", "disease": [ { "disease_id": "DOID:0110123", "name": "Bardet-Biedl syndrome 1", "description": "A Bardet-Biedl syndrome that has_material_basis_in homozygous mutation in the BBS1 gene on chromosome 11q13.", "url": "https://disease-ontology.org/term/DOID:0110123", "evidence": [ { "id": "0110123", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110123" } ], "weight": 0.0 }, { "disease_id": "DOID:1935", "name": "Bardet-Biedl syndrome", "description": "A syndrome that results from mutations in multiple BBS genes affecting cellular cilia structure or function (ciliopathy) resulting in variable presentation and characterized principally by obesity, retinitis pigmentosa,vision loss, polydactyly, mental retardation, hypogonadism, and renal failure in some cases.", "url": "https://disease-ontology.org/term/DOID:1935", "evidence": [ { "id": "1935", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1935" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "M0R957", "url": "https://www.uniprot.org/uniprotkb/M0R957" } ], "pmid": "" } ], "biological_process": [ { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "M0R957", "url": "https://www.uniprot.org/uniprotkb/M0R957" } ], "pmid": "" }, { "name": "social behavior", "id": "GO:0035176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035176", "evidence": [ { "database": "UniProtKB", "id": "M0R957", "url": "https://www.uniprot.org/uniprotkb/M0R957" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M0R957-1" }, { "uniprot_canonical_ac": "A0A8I6GJI1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GJI1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GJI1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 721, "chemical_mass": 82103.0, "gene_names": "Zfp551;Zfp551", "protein_name": "", "disease": [], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GJI1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GJI1" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GJI1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GJI1" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GJI1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GJI1" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GJI1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GJI1" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GJI1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GJI1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6GJI1-1" }, { "uniprot_canonical_ac": "F7EX11-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F7EX11", "url": "https://www.uniprot.org/uniprotkb/F7EX11" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 309, "chemical_mass": 35756.0, "gene_names": "Mnat1;Mnat1", "protein_name": "CDK-activating kinase assembly factor MAT1", "disease": [], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F7EX11", "url": "https://www.uniprot.org/uniprotkb/F7EX11" } ], "pmid": "" }, { "name": "cyclin-dependent protein serine/threonine kinase activator activity", "id": "GO:0061575", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061575", "evidence": [ { "database": "UniProtKB", "id": "F7EX11", "url": "https://www.uniprot.org/uniprotkb/F7EX11" } ], "pmid": "" } ], "cellular_component": [ { "name": "transcription factor TFIIH holo complex", "id": "GO:0005675", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005675", "evidence": [ { "database": "UniProtKB", "id": "F7EX11", "url": "https://www.uniprot.org/uniprotkb/F7EX11" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F7EX11", "url": "https://www.uniprot.org/uniprotkb/F7EX11" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F7EX11", "url": "https://www.uniprot.org/uniprotkb/F7EX11" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "F7EX11", "url": "https://www.uniprot.org/uniprotkb/F7EX11" } ], "pmid": "" }, { "name": "transcription factor TFIIK complex", "id": "GO:0070985", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070985", "evidence": [ { "database": "UniProtKB", "id": "F7EX11", "url": "https://www.uniprot.org/uniprotkb/F7EX11" } ], "pmid": "" }, { "name": "germinal vesicle", "id": "GO:0042585", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042585", "evidence": [ { "database": "UniProtKB", "id": "F7EX11", "url": "https://www.uniprot.org/uniprotkb/F7EX11" } ], "pmid": "" }, { "name": "cyclin-dependent protein kinase holoenzyme complex", "id": "GO:0000307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000307", "evidence": [ { "database": "UniProtKB", "id": "F7EX11", "url": "https://www.uniprot.org/uniprotkb/F7EX11" } ], "pmid": "" }, { "name": "transcription factor TFIIH core complex", "id": "GO:0000439", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000439", "evidence": [ { "database": "UniProtKB", "id": "F7EX11", "url": "https://www.uniprot.org/uniprotkb/F7EX11" } ], "pmid": "" }, { "name": "CAK-ERCC2 complex", "id": "GO:0070516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070516", "evidence": [ { "database": "UniProtKB", "id": "F7EX11", "url": "https://www.uniprot.org/uniprotkb/F7EX11" } ], "pmid": "" } ], "biological_process": [ { "name": "nucleotide-excision repair", "id": "GO:0006289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006289", "evidence": [ { "database": "UniProtKB", "id": "F7EX11", "url": "https://www.uniprot.org/uniprotkb/F7EX11" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F7EX11", "url": "https://www.uniprot.org/uniprotkb/F7EX11" } ], "pmid": "" }, { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "F7EX11", "url": "https://www.uniprot.org/uniprotkb/F7EX11" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "F7EX11", "url": "https://www.uniprot.org/uniprotkb/F7EX11" } ], "pmid": "" }, { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "F7EX11", "url": "https://www.uniprot.org/uniprotkb/F7EX11" } ], "pmid": "" }, { "name": "response to calcium ion", "id": "GO:0051592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051592", "evidence": [ { "database": "UniProtKB", "id": "F7EX11", "url": "https://www.uniprot.org/uniprotkb/F7EX11" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "F7EX11", "url": "https://www.uniprot.org/uniprotkb/F7EX11" } ], "pmid": "" }, { "name": "positive regulation of smooth muscle cell proliferation", "id": "GO:0048661", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048661", "evidence": [ { "database": "UniProtKB", "id": "F7EX11", "url": "https://www.uniprot.org/uniprotkb/F7EX11" } ], "pmid": "" }, { "name": "G1/S transition of mitotic cell cycle", "id": "GO:0000082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000082", "evidence": [ { "database": "UniProtKB", "id": "F7EX11", "url": "https://www.uniprot.org/uniprotkb/F7EX11" } ], "pmid": "" }, { "name": "transcription initiation at RNA polymerase II promoter", "id": "GO:0006367", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006367", "evidence": [ { "database": "UniProtKB", "id": "F7EX11", "url": "https://www.uniprot.org/uniprotkb/F7EX11" } ], "pmid": "" }, { "name": "ventricular system development", "id": "GO:0021591", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021591", "evidence": [ { "database": "UniProtKB", "id": "F7EX11", "url": "https://www.uniprot.org/uniprotkb/F7EX11" } ], "pmid": "" }, { "name": "adult heart development", "id": "GO:0007512", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007512", "evidence": [ { "database": "UniProtKB", "id": "F7EX11", "url": "https://www.uniprot.org/uniprotkb/F7EX11" } ], "pmid": "" }, { "name": "regulation of G1/S transition of mitotic cell cycle", "id": "GO:2000045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000045", "evidence": [ { "database": "UniProtKB", "id": "F7EX11", "url": "https://www.uniprot.org/uniprotkb/F7EX11" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F7EX11-1" }, { "uniprot_canonical_ac": "F7FCG9-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F7FCG9", "url": "https://www.uniprot.org/uniprotkb/F7FCG9" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 305, "chemical_mass": 34546.0, "gene_names": "Zc3h8;Zc3h8;Zc3hdc8", "protein_name": "", "disease": [], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "F7FCG9", "url": "https://www.uniprot.org/uniprotkb/F7FCG9" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F7FCG9", "url": "https://www.uniprot.org/uniprotkb/F7FCG9" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "F7FCG9", "url": "https://www.uniprot.org/uniprotkb/F7FCG9" } ], "pmid": "" }, { "name": "RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding", "id": "GO:0001162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001162", "evidence": [ { "database": "UniProtKB", "id": "F7FCG9", "url": "https://www.uniprot.org/uniprotkb/F7FCG9" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F7FCG9", "url": "https://www.uniprot.org/uniprotkb/F7FCG9" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F7FCG9", "url": "https://www.uniprot.org/uniprotkb/F7FCG9" } ], "pmid": "" }, { "name": "transcription elongation factor complex", "id": "GO:0008023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008023", "evidence": [ { "database": "UniProtKB", "id": "F7FCG9", "url": "https://www.uniprot.org/uniprotkb/F7FCG9" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "F7FCG9", "url": "https://www.uniprot.org/uniprotkb/F7FCG9" } ], "pmid": "" }, { "name": "Cajal body", "id": "GO:0015030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015030", "evidence": [ { "database": "UniProtKB", "id": "F7FCG9", "url": "https://www.uniprot.org/uniprotkb/F7FCG9" } ], "pmid": "" }, { "name": "euchromatin", "id": "GO:0000791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000791", "evidence": [ { "database": "UniProtKB", "id": "F7FCG9", "url": "https://www.uniprot.org/uniprotkb/F7FCG9" } ], "pmid": "" }, { "name": "histone locus body", "id": "GO:0035363", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035363", "evidence": [ { "database": "UniProtKB", "id": "F7FCG9", "url": "https://www.uniprot.org/uniprotkb/F7FCG9" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "F7FCG9", "url": "https://www.uniprot.org/uniprotkb/F7FCG9" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription, elongation", "id": "GO:0032785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032785", "evidence": [ { "database": "UniProtKB", "id": "F7FCG9", "url": "https://www.uniprot.org/uniprotkb/F7FCG9" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "F7FCG9", "url": "https://www.uniprot.org/uniprotkb/F7FCG9" } ], "pmid": "" }, { "name": "positive regulation of thymocyte apoptotic process", "id": "GO:0070245", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070245", "evidence": [ { "database": "UniProtKB", "id": "F7FCG9", "url": "https://www.uniprot.org/uniprotkb/F7FCG9" } ], "pmid": "" }, { "name": "response to antibiotic", "id": "GO:0046677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046677", "evidence": [ { "database": "UniProtKB", "id": "F7FCG9", "url": "https://www.uniprot.org/uniprotkb/F7FCG9" } ], "pmid": "" }, { "name": "T cell homeostasis", "id": "GO:0043029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043029", "evidence": [ { "database": "UniProtKB", "id": "F7FCG9", "url": "https://www.uniprot.org/uniprotkb/F7FCG9" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase III", "id": "GO:0045945", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045945", "evidence": [ { "database": "UniProtKB", "id": "F7FCG9", "url": "https://www.uniprot.org/uniprotkb/F7FCG9" } ], "pmid": "" }, { "name": "negative regulation of T cell differentiation in thymus", "id": "GO:0033085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033085", "evidence": [ { "database": "UniProtKB", "id": "F7FCG9", "url": "https://www.uniprot.org/uniprotkb/F7FCG9" } ], "pmid": "" }, { "name": "snRNA transcription by RNA polymerase II", "id": "GO:0042795", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042795", "evidence": [ { "database": "UniProtKB", "id": "F7FCG9", "url": "https://www.uniprot.org/uniprotkb/F7FCG9" } ], "pmid": "" }, { "name": "snRNA transcription by RNA polymerase III", "id": "GO:0042796", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042796", "evidence": [ { "database": "UniProtKB", "id": "F7FCG9", "url": "https://www.uniprot.org/uniprotkb/F7FCG9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F7FCG9-1" }, { "uniprot_canonical_ac": "A0A8I6AEQ1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEQ1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 631, "chemical_mass": 73521.0, "gene_names": "ENSRNOG00000067205;LOC103693502;LOC120093136;LOC120094816", "protein_name": "", "disease": [], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEQ1" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEQ1" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEQ1" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEQ1" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEQ1" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEQ1" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEQ1" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEQ1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AEQ1-1" }, { "uniprot_canonical_ac": "A0A8I6AF20-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AF20", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AF20" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 183, "chemical_mass": 20420.0, "gene_names": "ENSRNOG00000067749", "protein_name": "Ig-like domain-containing protein", "disease": [], "cellular_component": [ { "name": "T cell receptor complex", "id": "GO:0042101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042101", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AF20", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AF20" } ], "pmid": "" } ], "biological_process": [ { "name": "adaptive immune response", "id": "GO:0002250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002250", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AF20", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AF20" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AF20-1" }, { "uniprot_canonical_ac": "A0A8I6AFH3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AFH3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AFH3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 35, "chemical_mass": 3955.0, "gene_names": "ENSRNOG00000070330", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AFH3-1" }, { "uniprot_canonical_ac": "A0A8I6AHD0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHD0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHD0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 253, "chemical_mass": 28316.0, "gene_names": "Bri3bp;Bri3bp", "protein_name": "", "disease": [], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHD0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHD0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AHD0-1" }, { "uniprot_canonical_ac": "A0A8I6AHN0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHN0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHN0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 193, "chemical_mass": 21820.0, "gene_names": "LOC103690796;LOC103690796", "protein_name": "Large ribosomal subunit protein uL6", "disease": [], "molecular_function": [ { "name": "rRNA binding", "id": "GO:0019843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019843", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHN0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHN0" } ], "pmid": "" }, { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHN0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHN0" } ], "pmid": "" } ], "biological_process": [ { "name": "cytoplasmic translation", "id": "GO:0002181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002181", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHN0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHN0" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosolic large ribosomal subunit", "id": "GO:0022625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022625", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHN0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHN0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AHN0-1" }, { "uniprot_canonical_ac": "A0A8I6AHP9-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHP9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHP9" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 426, "chemical_mass": 49478.0, "gene_names": "LOC102555217;LOC102555217", "protein_name": "", "disease": [], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHP9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHP9" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHP9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHP9" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHP9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHP9" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHP9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHP9" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHP9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHP9" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHP9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHP9" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHP9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHP9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AHP9-1" }, { "uniprot_canonical_ac": "A0A8I6AI34-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AI34", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AI34" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 313, "chemical_mass": 35608.0, "gene_names": "Olr1471;Olr1471", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AI34", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AI34" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AI34", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AI34" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AI34", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AI34" } ], "pmid": "" } ], "biological_process": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AI34", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AI34" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AI34-1" }, { "uniprot_canonical_ac": "A0A8I6AIA3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AIA3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AIA3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 102, "chemical_mass": 11667.0, "gene_names": "ENSRNOG00000065493", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AIA3-1" }, { "uniprot_canonical_ac": "A0A8I6AJ21-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJ21", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJ21" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 395, "chemical_mass": 46328.0, "gene_names": "ENSRNOG00000063117", "protein_name": "LINE-1 retrotransposable element ORF1 protein", "disease": [], "biological_process": [ { "name": "retrotransposition", "id": "GO:0032197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032197", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJ21", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJ21" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJ21", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJ21" } ], "pmid": "" }, { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJ21", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJ21" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJ21", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJ21" } ], "pmid": "" } ], "molecular_function": [ { "name": "nucleotide binding", "id": "GO:0000166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000166", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJ21", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJ21" } ], "pmid": "" }, { "name": "single-stranded RNA binding", "id": "GO:0003727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003727", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJ21", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJ21" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AJ21-1" }, { "uniprot_canonical_ac": "A0A8I6AJ64-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJ64", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJ64" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 231, "chemical_mass": 24836.0, "gene_names": "Rfxap", "protein_name": "", "disease": [], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJ64", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJ64" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJ64", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJ64" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJ64", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJ64" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJ64", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJ64" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJ64", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJ64" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulator complex", "id": "GO:0090575", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090575", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJ64", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJ64" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJ64", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJ64" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJ64", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJ64" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJ64", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJ64" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AJ64-1" }, { "uniprot_canonical_ac": "A0A8I6AJN6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJN6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJN6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 331, "chemical_mass": 36888.0, "gene_names": "Mxd4", "protein_name": "", "disease": [ { "disease_id": "DOID:14330", "name": "Parkinson's disease", "description": "A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.", "url": "https://disease-ontology.org/term/DOID:14330", "evidence": [ { "id": "14330", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14330" } ], "weight": 0.0 } ], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJN6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJN6" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJN6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJN6" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJN6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJN6" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJN6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJN6" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJN6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJN6" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulator complex", "id": "GO:0090575", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090575", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJN6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJN6" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJN6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJN6" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJN6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJN6" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJN6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJN6" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJN6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJN6" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJN6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJN6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AJN6-1" }, { "uniprot_canonical_ac": "A0A8I6AKT3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AKT3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AKT3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 174, "chemical_mass": 19187.0, "gene_names": "H3f3bl1", "protein_name": "", "disease": [], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AKT3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AKT3" } ], "pmid": "" }, { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AKT3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AKT3" } ], "pmid": "" }, { "name": "structural constituent of chromatin", "id": "GO:0030527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030527", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AKT3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AKT3" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleosome", "id": "GO:0000786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000786", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AKT3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AKT3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AKT3-1" }, { "uniprot_canonical_ac": "A0A8I6ALL3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ALL3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ALL3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 184, "chemical_mass": 21231.0, "gene_names": "Tmem217b;Tmem217b", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6ALL3-1" }, { "uniprot_canonical_ac": "A0A8I6AM62-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AM62", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AM62" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 315, "chemical_mass": 35255.0, "gene_names": "Or5ae1;Olr10;Olr11;Or5ae1b;Or5ae1;ratchr1-141576128-141577075_ORF", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AM62", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AM62" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AM62", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AM62" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AM62", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AM62" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AM62", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AM62" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6AM62-1", "start_pos": "263", "end_pos": "263", "site_lbl": "Thr263", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 263, "start_aa": "Thr", "end_pos": 263, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr263", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6AM62-1" }, { "uniprot_canonical_ac": "A0A8I6AMI9-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AMI9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AMI9" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 150, "chemical_mass": 16674.0, "gene_names": "ENSRNOG00000066262", "protein_name": "Ubiquitin-like protein 4A", "disease": [], "biological_process": [ { "name": "post-translational protein targeting to endoplasmic reticulum membrane", "id": "GO:0006620", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006620", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AMI9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AMI9" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AMI9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AMI9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AMI9-1" }, { "uniprot_canonical_ac": "A0A8I6AMX7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AMX7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AMX7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 397, "chemical_mass": 46450.0, "gene_names": "Znf431l-ps8", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6AMX7-1", "start_pos": "191", "end_pos": "191", "site_lbl": "Thr191", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 191, "start_aa": "Thr", "end_pos": 191, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr191", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6AMX7-1" }, { "uniprot_canonical_ac": "A0A8I6APG8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6APG8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6APG8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 129, "chemical_mass": 15179.0, "gene_names": "LOC120094308;LOC120094308", "protein_name": "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4", "disease": [], "cellular_component": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6APG8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6APG8" } ], "pmid": "" }, { "name": "respiratory chain complex I", "id": "GO:0045271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045271", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6APG8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6APG8" } ], "pmid": "" } ], "biological_process": [ { "name": "respiratory electron transport chain", "id": "GO:0022904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022904", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6APG8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6APG8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6APG8-1" }, { "uniprot_canonical_ac": "A0A8I6APM3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6APM3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6APM3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 61, "chemical_mass": 7135.0, "gene_names": "ENSRNOG00000068204", "protein_name": "KRAB domain-containing protein", "disease": [], "biological_process": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6APM3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6APM3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6APM3-1" }, { "uniprot_canonical_ac": "A0A8I6AQ52-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQ52", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQ52" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 365, "chemical_mass": 41367.0, "gene_names": "RT1-S3;H2-T23;RT-BM1;RT1-BM1;RT1-S3;RTBM1", "protein_name": "", "disease": [ { "disease_id": "DOID:0050426", "name": "Stevens-Johnson syndrome", "description": "A skin disease that is characterized by ulceration of less than 10 percent of the surface area of the body. The disease is often precipitated by the use of medications, such as antibiotics or antiepileptics, or onset of infection.", "url": "https://disease-ontology.org/term/DOID:0050426", "evidence": [ { "id": "0050426", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050426" } ], "weight": 0.0 }, { "disease_id": "DOID:0060180", "name": "colitis", "description": "An inflammatory bowel disease that involves inflammation located_in colon.", "url": "https://disease-ontology.org/term/DOID:0060180", "evidence": [ { "id": "0060180", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060180" } ], "weight": 0.0 }, { "disease_id": "DOID:0080160", "name": "Cytomegalovirus retinitis", "description": "A retinitis that has_material_basis_in Cytomegalovirus.", "url": "https://disease-ontology.org/term/DOID:0080160", "evidence": [ { "id": "0080160", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080160" } ], "weight": 0.0 }, { "disease_id": "DOID:0080600", "name": "COVID-19", "description": "A Coronavirus infectious disease that is characterized by fever, cough and shortness of breath and that has_material_basis_in Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a subtype of Betacoronavirus pandemicum.", "url": "https://disease-ontology.org/term/DOID:0080600", "evidence": [ { "id": "0080600", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080600" } ], "weight": 0.0 }, { "disease_id": "DOID:0080603", "name": "ankylosing spondylitis 1", "description": "A ankylosing spondylitis that has_material_basis_in variation in the HLA-B27 allele on chromosome 6p21.3.", "url": "https://disease-ontology.org/term/DOID:0080603", "evidence": [ { "id": "0080603", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080603" } ], "weight": 0.0 }, { "disease_id": "DOID:0080750", "name": "erythema nodosum", "description": "A panniculitis that is characterized by sudden onset of painful, erythematous, subcutaneous nodules mainly localized to the pretibial areas. Lesions are usually bilateral and symmetrical, ranging from 1 to 5 cm in diameter.", "url": "https://disease-ontology.org/term/DOID:0080750", "evidence": [ { "id": "0080750", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080750" } ], "weight": 0.0 }, { "disease_id": "DOID:0080820", "name": "occupational asthma", "description": "An environmental induced asthma that is characterized by a variable airflow limitation due to exposure to inhaled irritants in the workplace.", "url": "https://disease-ontology.org/term/DOID:0080820", "evidence": [ { "id": "0080820", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080820" } ], "weight": 0.0 }, { "disease_id": "DOID:0111079", "name": "birdshot chorioretinopathy", "description": "A posterior uveitis characterized by multiple small, hypopigmented, cream-colored choroidal lesions scattered symmetrically in the fundus primarily around the optic disc that presents in patients as blurred vision, floaters, photopsia, scotoma and nyctalopia.", "url": "https://disease-ontology.org/term/DOID:0111079", "evidence": [ { "id": "0111079", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111079" } ], "weight": 0.0 }, { "disease_id": "DOID:0111286", "name": "psoriasis 1", "description": "A psoriasis that has_material_basis_in variation in the HLA-C gene on chromosome 6p21.33.", "url": "https://disease-ontology.org/term/DOID:0111286", "evidence": [ { "id": "0111286", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111286" } ], "weight": 0.0 }, { "disease_id": "DOID:10003", "name": "sensorineural hearing loss", "description": "An inner ear disease that is characterized by hearing loss resulting from damage to the cochlea, auditory nerve and/or brainstem.", "url": "https://disease-ontology.org/term/DOID:10003", "evidence": [ { "id": "10003", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10003" } ], "weight": 0.0 }, { "disease_id": "DOID:1123", "name": "spondyloarthropathy", "description": "", "url": "https://disease-ontology.org/term/DOID:1123", "evidence": [ { "id": "1123", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1123" } ], "weight": 0.0 }, { "disease_id": "DOID:11265", "name": "trachoma", "description": "A commensal bacterial infectious disease that results_in infection located_in eye, has_material_basis_in Chlamydia trachomatis (A, B, Ba and C serovars), which is transmitted_by contact with eye discharge from the infected person and transmitted_by congenital method. The infection causes eyelid to turn inward which makes eyelashes to scratch the cornea.", "url": "https://disease-ontology.org/term/DOID:11265", "evidence": [ { "id": "11265", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11265" } ], "weight": 0.0 }, { "disease_id": "DOID:11335", "name": "sarcoidosis", "description": "A hypersensitivity reaction type IV disease characterized by the growth of collections of inflammatory cells (granulomas) in multiple organs.", "url": "https://disease-ontology.org/term/DOID:11335", "evidence": [ { "id": "11335", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11335" } ], "weight": 0.0 }, { "disease_id": "DOID:11563", "name": "retinal vasculitis", "description": "A vasculitis that is characterized by inflammation of the vascular branches of the retinal artery and has_symptom painless decrease of visual acuity, visual floaters, dark spot in vision, decreased ability to distinguish colors, and distortion of images such as linear images.", "url": "https://disease-ontology.org/term/DOID:11563", "evidence": [ { "id": "11563", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11563" } ], "weight": 0.0 }, { "disease_id": "DOID:12185", "name": "otosclerosis", "description": "An otitis interna characterized by isolated endochondral bone sclerosis of the labyrinthine capsule.", "url": "https://disease-ontology.org/term/DOID:12185", "evidence": [ { "id": "12185", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12185" } ], "weight": 0.0 }, { "disease_id": "DOID:12361", "name": "Graves' disease", "description": "An autoimmune disease of endocrine system that involves production of excessive amount of thyroid hormones, located_in thyroid gland.", "url": "https://disease-ontology.org/term/DOID:12361", "evidence": [ { "id": "12361", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12361" } ], "weight": 0.0 }, { "disease_id": "DOID:13025", "name": "retinopathy of prematurity", "description": "", "url": "https://disease-ontology.org/term/DOID:13025", "evidence": [ { "id": "13025", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13025" } ], "weight": 0.0 }, { "disease_id": "DOID:13141", "name": "uveitis", "description": "An uveal disease is characterized by inflammation of any of the layers of the uvea of the eye, which includes the iris, ciliary body, and choroid.", "url": "https://disease-ontology.org/term/DOID:13141", "evidence": [ { "id": "13141", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13141" } ], "weight": 0.0 }, { "disease_id": "DOID:13241", "name": "Behcet's disease", "description": "An autoimmune disease that is characterized by mucocutaneous manifestations, including recurrent oral and genital ulcerations, ocular manifestations, especially chronic relapsing uveitis, and systemic vasculitis involving arteries and veins of all sizes.", "url": "https://disease-ontology.org/term/DOID:13241", "evidence": [ { "id": "13241", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13241" } ], "weight": 0.0 }, { "disease_id": "DOID:1407", "name": "anterior uveitis", "description": "", "url": "https://disease-ontology.org/term/DOID:1407", "evidence": [ { "id": "1407", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1407" } ], "weight": 0.0 }, { "disease_id": "DOID:2508", "name": "Takayasu's arteritis", "description": "A vasculitis that involves inflammation of the aorta that carries blood from the heart to the rest of the body.", "url": "https://disease-ontology.org/term/DOID:2508", "evidence": [ { "id": "2508", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2508" } ], "weight": 0.0 }, { "disease_id": "DOID:2703", "name": "synovitis", "description": "A connective tissue disease that results_in inflammation located_in synovial membrane that lines a synovial joint which causes pain and swelling.", "url": "https://disease-ontology.org/term/DOID:2703", "evidence": [ { "id": "2703", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2703" } ], "weight": 0.0 }, { "disease_id": "DOID:2723", "name": "dermatitis", "description": "A skin disease characterized by itchy, erythematous, vesicular, weeping and crusting patches of skin.", "url": "https://disease-ontology.org/term/DOID:2723", "evidence": [ { "id": "2723", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2723" } ], "weight": 0.0 }, { "disease_id": "DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.", "url": "https://disease-ontology.org/term/DOID:2841", "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ], "weight": 0.0 }, { "disease_id": "DOID:2945", "name": "severe acute respiratory syndrome", "description": "A Coronavirus infectious disease that results_in infection located_in respiratory tract, has_material_basis_in Severe acute respiratory syndrome coronavirus (SARS-CoV or SARS-CoV-1), a subtype of Betacoronavirus pandemicum, which is transmitted_by droplet spread of respiratory secretions, transmitted_by ingestion of contaminated food, or transmitted_by fomites. The infection has_symptom fever, has_symptom headache, has_symptom body aches, has_symptom dry cough, and has_symptom hypoxia.", "url": "https://disease-ontology.org/term/DOID:2945", "evidence": [ { "id": "2945", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2945" } ], "weight": 0.0 }, { "disease_id": "DOID:3526", "name": "cerebral infarction", "description": "A cerebrovascular disease that is characterized by an area of necrotic tissue in the brain resulting from a blockage or narrowing in the arteries supplying blood and oxygen to the brain.", "url": "https://disease-ontology.org/term/DOID:3526", "evidence": [ { "id": "3526", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3526" } ], "weight": 0.0 }, { "disease_id": "DOID:3611", "name": "acute retinal necrosis syndrome", "description": "", "url": "https://disease-ontology.org/term/DOID:3611", "evidence": [ { "id": "3611", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3611" } ], "weight": 0.0 }, { "disease_id": "DOID:3875", "name": "thrombophlebitis", "description": "A phlebitis that results from a blood clot in the vessel.", "url": "https://disease-ontology.org/term/DOID:3875", "evidence": [ { "id": "3875", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3875" } ], "weight": 0.0 }, { "disease_id": "DOID:399", "name": "tuberculosis", "description": "A primary bacterial infectious disease that is located_in lungs, located_in lymph nodes, located_in pericardium, located_in brain, located_in pleura or located_in gastrointestinal tract, has_material_basis_in Mycobacterium tuberculosis, which is transmitted_by droplets released into the air when an infected person coughs or sneezes.", "url": "https://disease-ontology.org/term/DOID:399", "evidence": [ { "id": "399", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:399" } ], "weight": 0.0 }, { "disease_id": "DOID:4362", "name": "cervical cancer", "description": "A female reproductive organ cancer that is located_in the cervix.", "url": "https://disease-ontology.org/term/DOID:4362", "evidence": [ { "id": "4362", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4362" } ], "weight": 0.0 }, { "disease_id": "DOID:526", "name": "human immunodeficiency virus infectious disease", "description": "A viral infectious disease that results in destruction of immune system, leading to life-threatening opportunistic infections and cancers, has_material_basis_in Human immunodeficiency virus 1 (Lentivirus humimdef1) or Human immunodeficiency virus 2 (Lentivirus humimdef2), which are transmitted by sexual contact, transmitted by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted by congenital method, and transmitted by contaminated needles. The virus infects helper T cells (CD4+ T cells) which are directly or indirectly destroyed, macrophages, and dendritic cells. The infection has symptom diarrhea, has symptom fatigue, has symptom fever, has symptom vaginal yeast infection, has symptom headache, has symptom mouth sores, has symptom muscle aches, has symptom sore throat, and has symptom swollen lymph glands.", "url": "https://disease-ontology.org/term/DOID:526", "evidence": [ { "id": "526", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:526" } ], "weight": 0.0 }, { "disease_id": "DOID:6039", "name": "uveal melanoma", "description": "A uveal cancer that has_material_basis_in uvea pigment cells.", "url": "https://disease-ontology.org/term/DOID:6039", "evidence": [ { "id": "6039", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6039" } ], "weight": 0.0 }, { "disease_id": "DOID:6196", "name": "reactive arthritis", "description": "An arthritis that is an autoimmune disease which develops due to an infection located elsewhere in the body.", "url": "https://disease-ontology.org/term/DOID:6196", "evidence": [ { "id": "6196", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6196" } ], "weight": 0.0 }, { "disease_id": "DOID:7147", "name": "ankylosing spondylitis", "description": "An arthritis that results_in inflammation in the joints of the spine and pelvis. The disease has_symptom pain, has_symptom stiffness in the spine, has_symptom stiffness in the neck, has_symptom stiffness in the hips, has_symptom stiffness in the jaw and has_symptom stiffness in the rib cage.", "url": "https://disease-ontology.org/term/DOID:7147", "evidence": [ { "id": "7147", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7147" } ], "weight": 0.0 }, { "disease_id": "DOID:8947", "name": "diabetic retinopathy", "description": "", "url": "https://disease-ontology.org/term/DOID:8947", "evidence": [ { "id": "8947", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8947" } ], "weight": 0.0 }, { "disease_id": "DOID:9415", "name": "allergic asthma", "description": "An extrinsic asthma that is characterized by symptoms that are triggered by an allergic reaction caused by inhaled allergens such as dust mite allergen, pet dander, pollen and mold. The disease has_symptom coughing, has_symptom wheezing, has_symptom shortness of breath or has_symptom rapid breathing, and has_symptom chest tightness.", "url": "https://disease-ontology.org/term/DOID:9415", "evidence": [ { "id": "9415", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9415" } ], "weight": 0.0 }, { "disease_id": "DOID:9849", "name": "Meniere's disease", "description": "A vestibular disease characterized by vertigo, low-pitched tinnitus and hearing loss.", "url": "https://disease-ontology.org/term/DOID:9849", "evidence": [ { "id": "9849", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9849" } ], "weight": 0.0 }, { "disease_id": "DOID:987", "name": "alopecia", "description": "A hypotrichosis that is characterized by a loss of hair from the head or body.", "url": "https://disease-ontology.org/term/DOID:987", "evidence": [ { "id": "987", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:987" } ], "weight": 0.0 }, { "disease_id": "DOID:988", "name": "mitral valve prolapse", "description": "A mitral valve disease where one or both of the cusps of the mitral valve bulge or collapse backward in the left atrium during systole.", "url": "https://disease-ontology.org/term/DOID:988", "evidence": [ { "id": "988", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:988" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQ52", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQ52" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AQ52-1" }, { "uniprot_canonical_ac": "A0A8I6AQD7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQD7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQD7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 110, "chemical_mass": 11973.0, "gene_names": "ENSRNOG00000064041", "protein_name": "Ig-like domain-containing protein", "disease": [], "biological_process": [ { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQD7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQD7" } ], "pmid": "" } ], "cellular_component": [ { "name": "immunoglobulin complex", "id": "GO:0019814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019814", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQD7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQD7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AQD7-1" }, { "uniprot_canonical_ac": "A0A8I6AQK1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQK1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQK1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 578, "chemical_mass": 66383.0, "gene_names": "Zfp950l14;LOC102548076", "protein_name": "", "disease": [], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQK1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQK1" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQK1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQK1" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQK1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQK1" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQK1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQK1" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQK1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQK1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AQK1-1" }, { "uniprot_canonical_ac": "A0A8I6AQZ8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQZ8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 169, "chemical_mass": 19486.0, "gene_names": "Ube2g1l1;LOC100363427", "protein_name": "Ubiquitin-conjugating enzyme E2 G1", "disease": [], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQZ8" } ], "pmid": "" }, { "name": "ubiquitin conjugating enzyme activity", "id": "GO:0061631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061631", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQZ8" } ], "pmid": "" } ], "biological_process": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQZ8" } ], "pmid": "" }, { "name": "protein polyubiquitination", "id": "GO:0000209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000209", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQZ8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AQZ8-1" }, { "uniprot_canonical_ac": "A0A8I6AR28-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AR28", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AR28" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 558, "chemical_mass": 63944.0, "gene_names": "Traf5;Traf5", "protein_name": "TNF receptor-associated factor", "disease": [], "biological_process": [ { "name": "CD40 signaling pathway", "id": "GO:0023035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0023035", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AR28", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AR28" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AR28", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AR28" } ], "pmid": "" }, { "name": "cell surface receptor signaling pathway", "id": "GO:0007166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007166", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AR28", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AR28" } ], "pmid": "" }, { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AR28", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AR28" } ], "pmid": "" }, { "name": "mRNA stabilization", "id": "GO:0048255", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048255", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AR28", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AR28" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AR28", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AR28" } ], "pmid": "" }, { "name": "positive regulation of canonical NF-kappaB signal transduction", "id": "GO:0043123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043123", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AR28", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AR28" } ], "pmid": "" }, { "name": "regulation of apoptotic process", "id": "GO:0042981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042981", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AR28", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AR28" } ], "pmid": "" }, { "name": "tumor necrosis factor-mediated signaling pathway", "id": "GO:0033209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033209", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AR28", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AR28" } ], "pmid": "" }, { "name": "regulation of canonical NF-kappaB signal transduction", "id": "GO:0043122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043122", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AR28", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AR28" } ], "pmid": "" }, { "name": "interleukin-17-mediated signaling pathway", "id": "GO:0097400", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097400", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AR28", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AR28" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AR28", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AR28" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AR28", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AR28" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AR28", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AR28" } ], "pmid": "" }, { "name": "cytoplasmic side of plasma membrane", "id": "GO:0009898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009898", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AR28", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AR28" } ], "pmid": "" }, { "name": "CD40 receptor complex", "id": "GO:0035631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035631", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AR28", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AR28" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AR28", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AR28" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AR28", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AR28" } ], "pmid": "" }, { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AR28", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AR28" } ], "pmid": "" }, { "name": "thioesterase binding", "id": "GO:0031996", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031996", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AR28", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AR28" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AR28", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AR28" } ], "pmid": "" }, { "name": "signaling adaptor activity", "id": "GO:0035591", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035591", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AR28", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AR28" } ], "pmid": "" }, { "name": "tumor necrosis factor receptor binding", "id": "GO:0005164", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005164", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AR28", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AR28" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AR28-1" }, { "uniprot_canonical_ac": "A0A8I6ARJ3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ARJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ARJ3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 309, "chemical_mass": 34547.0, "gene_names": "Or8b101l1;Olfr883", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ARJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ARJ3" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ARJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ARJ3" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ARJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ARJ3" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ARJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ARJ3" } ], "pmid": "" } ], "biological_process": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ARJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ARJ3" } ], "pmid": "" }, { "name": "sensory perception of smell", "id": "GO:0007608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007608", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ARJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ARJ3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6ARJ3-1" }, { "uniprot_canonical_ac": "A0A8I6ARX1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ARX1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ARX1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 641, "chemical_mass": 75287.0, "gene_names": "Zfp948;LOC102550851;Zfp948", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ARX1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ARX1" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ARX1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ARX1" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ARX1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ARX1" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ARX1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ARX1" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ARX1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ARX1" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ARX1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ARX1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6ARX1-1" }, { "uniprot_canonical_ac": "A0A8I6GAR2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GAR2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GAR2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1964, "chemical_mass": 210671.0, "gene_names": "Tnrc6a;Tnrc6a;Tnrc6", "protein_name": "", "disease": [ { "disease_id": "DOID:0111696", "name": "familial adult myoclonic epilepsy 6", "description": "A familial adult myoclonic epilepsy that has_material_basis_in a heterozygous 5-bp repeat expansion in the TNRC6A gene on chromosome 16p12.1.", "url": "https://disease-ontology.org/term/DOID:0111696", "evidence": [ { "id": "0111696", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111696" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GAR2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GAR2" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GAR2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GAR2" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GAR2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GAR2" } ], "pmid": "" }, { "name": "P-body", "id": "GO:0000932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000932", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GAR2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GAR2" } ], "pmid": "" }, { "name": "RISC complex", "id": "GO:0016442", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016442", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GAR2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GAR2" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of translation", "id": "GO:0006417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006417", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GAR2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GAR2" } ], "pmid": "" }, { "name": "regulatory ncRNA-mediated gene silencing", "id": "GO:0031047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031047", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GAR2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GAR2" } ], "pmid": "" }, { "name": "cellular response to starvation", "id": "GO:0009267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009267", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GAR2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GAR2" } ], "pmid": "" }, { "name": "miRNA-mediated gene silencing by inhibition of translation", "id": "GO:0035278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035278", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GAR2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GAR2" } ], "pmid": "" }, { "name": "positive regulation of nuclear-transcribed mRNA poly(A) tail shortening", "id": "GO:0060213", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060213", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GAR2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GAR2" } ], "pmid": "" }, { "name": "miRNA-mediated post-transcriptional gene silencing", "id": "GO:0035195", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035195", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GAR2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GAR2" } ], "pmid": "" }, { "name": "endoderm development", "id": "GO:0007492", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007492", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GAR2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GAR2" } ], "pmid": "" }, { "name": "P-body assembly", "id": "GO:0033962", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033962", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GAR2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GAR2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6GAR2-1", "start_pos": "1072", "end_pos": "1072", "site_lbl": "Thr1072", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1072, "start_aa": "Thr", "end_pos": 1072, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1072", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I6GAR2-1", "start_pos": "1635", "end_pos": "1635", "site_lbl": "Thr1635", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1635, "start_aa": "Thr", "end_pos": 1635, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1635", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6GAR2-1" }, { "uniprot_canonical_ac": "A0A8I6AUG1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AUG1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AUG1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 259, "chemical_mass": 29365.0, "gene_names": "AABR07072440.1", "protein_name": "60S ribosomal protein L7a", "disease": [], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AUG1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AUG1" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosolic large ribosomal subunit", "id": "GO:0022625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022625", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AUG1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AUG1" } ], "pmid": "" } ], "biological_process": [ { "name": "maturation of LSU-rRNA", "id": "GO:0000470", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000470", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AUG1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AUG1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AUG1-1" }, { "uniprot_canonical_ac": "A0A8I6AUI5-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AUI5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AUI5" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 170, "chemical_mass": 18975.0, "gene_names": "Cpsf4-ps1", "protein_name": "Cleavage and polyadenylation specificity factor subunit 4", "disease": [], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AUI5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AUI5" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AUI5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AUI5" } ], "pmid": "" } ], "cellular_component": [ { "name": "mRNA cleavage and polyadenylation specificity factor complex", "id": "GO:0005847", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005847", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AUI5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AUI5" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA 3'-end processing", "id": "GO:0031124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031124", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AUI5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AUI5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AUI5-1" }, { "uniprot_canonical_ac": "A0A8I6AUU4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AUU4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AUU4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 126, "chemical_mass": 14305.0, "gene_names": "LOC103693281", "protein_name": "Activated RNA polymerase II transcriptional coactivator p15", "disease": [], "biological_process": [ { "name": "positive regulation of transcription initiation by RNA polymerase II", "id": "GO:0060261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060261", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AUU4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AUU4" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AUU4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AUU4" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AUU4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AUU4" } ], "pmid": "" }, { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AUU4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AUU4" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AUU4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AUU4" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AUU4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AUU4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AUU4-1" }, { "uniprot_canonical_ac": "A0A8I6B3Q2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B3Q2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B3Q2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 294, "chemical_mass": 31949.0, "gene_names": "Plpp5", "protein_name": "", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B3Q2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B3Q2" } ], "pmid": "" } ], "biological_process": [ { "name": "phospholipid metabolic process", "id": "GO:0006644", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006644", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B3Q2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B3Q2" } ], "pmid": "" }, { "name": "phospholipid dephosphorylation", "id": "GO:0046839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046839", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B3Q2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B3Q2" } ], "pmid": "" } ], "molecular_function": [ { "name": "phosphatidate phosphatase activity", "id": "GO:0008195", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008195", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B3Q2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B3Q2" } ], "pmid": "" }, { "name": "diacylglycerol diphosphate phosphatase activity", "id": "GO:0000810", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000810", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B3Q2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B3Q2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6B3Q2-1" }, { "uniprot_canonical_ac": "A0A8I6G1P7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G1P7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G1P7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 136, "chemical_mass": 15128.0, "gene_names": "ENSRNOG00000062657", "protein_name": "Ig-like domain-containing protein", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G1P7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G1P7" } ], "pmid": "" }, { "name": "immunoglobulin complex", "id": "GO:0019814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019814", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G1P7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G1P7" } ], "pmid": "" } ], "molecular_function": [ { "name": "antigen binding", "id": "GO:0003823", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003823", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G1P7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G1P7" } ], "pmid": "" } ], "biological_process": [ { "name": "immunoglobulin mediated immune response", "id": "GO:0016064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016064", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G1P7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G1P7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6G1P7-1" }, { "uniprot_canonical_ac": "A0A8I6G380-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G380", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G380" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 552, "chemical_mass": 59426.0, "gene_names": "LOC100365213;Krt6a", "protein_name": "", "disease": [ { "disease_id": "DOID:0050449", "name": "pachyonychia congenita", "description": "A syndrome that is characterized by hypertrophic nails and hyperkeratosis of the hands and feet and has_material_basis_in gene mutations that result in changes in keratin.", "url": "https://disease-ontology.org/term/DOID:0050449", "evidence": [ { "id": "0050449", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050449" } ], "weight": 0.0 }, { "disease_id": "DOID:0111710", "name": "focal or diffuse nonepidermolytic palmoplantar keratoderma", "description": "A nonepidermolytic palmoplantar keratoderma characterized by focal or diffuse palmoplantar keratodermas with minor or absent nail changes that has_material_basis_in heterozygous mutation in the KRT6C gene on chromosome 12q13.13.", "url": "https://disease-ontology.org/term/DOID:0111710", "evidence": [ { "id": "0111710", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111710" } ], "weight": 0.0 } ], "biological_process": [ { "name": "keratinization", "id": "GO:0031424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031424", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G380", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G380" } ], "pmid": "" }, { "name": "intermediate filament organization", "id": "GO:0045109", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045109", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G380", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G380" } ], "pmid": "" } ], "cellular_component": [ { "name": "keratin filament", "id": "GO:0045095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045095", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G380", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G380" } ], "pmid": "" } ], "molecular_function": [ { "name": "structural constituent of skin epidermis", "id": "GO:0030280", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030280", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G380", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G380" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6G380-1" }, { "uniprot_canonical_ac": "A0A8I6G430-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G430", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G430" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 193, "chemical_mass": 21536.0, "gene_names": "LOC689816", "protein_name": "Large ribosomal subunit protein eL24", "disease": [], "cellular_component": [ { "name": "ribosome", "id": "GO:0005840", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005840", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G430", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G430" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G430", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G430" } ], "pmid": "" } ], "molecular_function": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G430", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G430" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6G430-1" }, { "uniprot_canonical_ac": "A0A8I6G723-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G723", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G723" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 127, "chemical_mass": 14206.0, "gene_names": "ENSRNOG00000067546", "protein_name": "Ig-like domain-containing protein", "disease": [], "cellular_component": [ { "name": "T cell receptor complex", "id": "GO:0042101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042101", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G723", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G723" } ], "pmid": "" }, { "name": "immunoglobulin complex", "id": "GO:0019814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019814", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G723", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G723" } ], "pmid": "" } ], "biological_process": [ { "name": "adaptive immune response", "id": "GO:0002250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002250", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G723", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G723" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6G723-1" }, { "uniprot_canonical_ac": "A0A8I5ZKU1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZKU1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZKU1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 326, "chemical_mass": 37214.0, "gene_names": "C1h19orf81;RGD1309036", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZKU1-1" }, { "uniprot_canonical_ac": "A0A8I6GA77-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GA77", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GA77" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 104, "chemical_mass": 11156.0, "gene_names": "ENSRNOG00000070134", "protein_name": "Ig-like domain-containing protein", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GA77", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GA77" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GA77", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GA77" } ], "pmid": "" }, { "name": "immunoglobulin complex", "id": "GO:0019814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019814", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GA77", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GA77" } ], "pmid": "" } ], "biological_process": [ { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GA77", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GA77" } ], "pmid": "" }, { "name": "adaptive immune response", "id": "GO:0002250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002250", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GA77", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GA77" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6GA77-1" }, { "uniprot_canonical_ac": "A0A8I6GBS7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GBS7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GBS7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 561, "chemical_mass": 65787.0, "gene_names": "ENSRNOG00000070049", "protein_name": "Zinc finger protein 431-like", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GBS7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GBS7" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GBS7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GBS7" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GBS7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GBS7" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GBS7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GBS7" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GBS7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GBS7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6GBS7-1" }, { "uniprot_canonical_ac": "A0A8I6GDK9-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GDK9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GDK9" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 357, "chemical_mass": 41892.0, "gene_names": "ENSRNOG00000064845", "protein_name": "LINE-1 retrotransposable element ORF1 protein", "disease": [], "biological_process": [ { "name": "retrotransposition", "id": "GO:0032197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032197", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GDK9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GDK9" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GDK9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GDK9" } ], "pmid": "" }, { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GDK9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GDK9" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GDK9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GDK9" } ], "pmid": "" } ], "molecular_function": [ { "name": "nucleotide binding", "id": "GO:0000166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000166", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GDK9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GDK9" } ], "pmid": "" }, { "name": "single-stranded RNA binding", "id": "GO:0003727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003727", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GDK9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GDK9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6GDK9-1" }, { "uniprot_canonical_ac": "A0A8I6GDX5-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GDX5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GDX5" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 66, "chemical_mass": 7750.0, "gene_names": "LOC120094392", "protein_name": "", "disease": [], "molecular_function": [ { "name": "actin monomer binding", "id": "GO:0003785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003785", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GDX5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GDX5" } ], "pmid": "" }, { "name": "protein sequestering activity", "id": "GO:0140311", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140311", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GDX5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GDX5" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GDX5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GDX5" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GDX5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GDX5" } ], "pmid": "" } ], "biological_process": [ { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GDX5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GDX5" } ], "pmid": "" }, { "name": "regulation of cell migration", "id": "GO:0030334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030334", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GDX5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GDX5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6GDX5-1" }, { "uniprot_canonical_ac": "A0A8I6GE36-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GE36", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GE36" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 121, "chemical_mass": 13374.0, "gene_names": "ENSRNOG00000070832", "protein_name": "Ig-like domain-containing protein", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GE36", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GE36" } ], "pmid": "" }, { "name": "immunoglobulin complex", "id": "GO:0019814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019814", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GE36", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GE36" } ], "pmid": "" } ], "molecular_function": [ { "name": "antigen binding", "id": "GO:0003823", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003823", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GE36", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GE36" } ], "pmid": "" } ], "biological_process": [ { "name": "immunoglobulin mediated immune response", "id": "GO:0016064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016064", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GE36", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GE36" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6GE36-1" }, { "uniprot_canonical_ac": "A0A8I6GFF5-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GFF5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GFF5" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 98, "chemical_mass": 11107.0, "gene_names": "LOC100362296;LOC100362296", "protein_name": "EF-hand domain-containing protein", "disease": [], "biological_process": [ { "name": "regulation of cell population proliferation", "id": "GO:0042127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042127", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GFF5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GFF5" } ], "pmid": "" } ], "molecular_function": [ { "name": "calcium-dependent protein binding", "id": "GO:0048306", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048306", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GFF5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GFF5" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GFF5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GFF5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6GFF5-1" }, { "uniprot_canonical_ac": "A0A8I6GFK7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GFK7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GFK7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 317, "chemical_mass": 36471.0, "gene_names": "C15h13orf42;LOC102554746", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6GFK7-1" }, { "uniprot_canonical_ac": "A0A8I6GGL0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GGL0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GGL0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 556, "chemical_mass": 63639.0, "gene_names": "Zfp101;RGD1560314", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GGL0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GGL0" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GGL0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GGL0" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GGL0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GGL0" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GGL0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GGL0" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GGL0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GGL0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6GGL0-1" }, { "uniprot_canonical_ac": "A0A8I6GGX3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GGX3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GGX3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 314, "chemical_mass": 35405.0, "gene_names": "Or8g35b;Olr1297;Or8g35b", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GGX3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GGX3" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GGX3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GGX3" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GGX3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GGX3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6GGX3-1" }, { "uniprot_canonical_ac": "A0A8I6GJT3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GJT3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GJT3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 475, "chemical_mass": 52346.0, "gene_names": "LOC100361636;LOC100361636", "protein_name": "", "disease": [], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GJT3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GJT3" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GJT3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GJT3" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GJT3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GJT3" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GJT3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GJT3" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GJT3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GJT3" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GJT3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GJT3" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GJT3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GJT3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6GJT3-1" }, { "uniprot_canonical_ac": "A0A8I6GJX9-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GJX9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GJX9" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 685, "chemical_mass": 71345.0, "gene_names": "Insm1", "protein_name": "Insulinoma-associated protein 1", "disease": [ { "disease_id": "DOID:1319", "name": "brain cancer", "description": "A central nervous system cancer that is characterized by the growth of abnormal cells in the tissues of the brain.", "url": "https://disease-ontology.org/term/DOID:1319", "evidence": [ { "id": "1319", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1319" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GJX9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GJX9" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GJX9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GJX9" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GJX9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GJX9" } ], "pmid": "" }, { "name": "histone deacetylase binding", "id": "GO:0042826", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042826", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GJX9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GJX9" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GJX9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GJX9" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GJX9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GJX9" } ], "pmid": "" }, { "name": "chromatin DNA binding", "id": "GO:0031490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031490", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GJX9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GJX9" } ], "pmid": "" }, { "name": "cyclin binding", "id": "GO:0030332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030332", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GJX9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GJX9" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GJX9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GJX9" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GJX9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GJX9" } ], "pmid": "" }, { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GJX9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GJX9" } ], "pmid": "" }, { "name": "negative regulation of cell population proliferation", "id": "GO:0008285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008285", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GJX9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GJX9" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GJX9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GJX9" } ], "pmid": "" }, { "name": "positive regulation of cell migration", "id": "GO:0030335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030335", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GJX9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GJX9" } ], "pmid": "" }, { "name": "negative regulation of protein phosphorylation", "id": "GO:0001933", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001933", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GJX9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GJX9" } ], "pmid": "" }, { "name": "positive regulation of cell differentiation", "id": "GO:0045597", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045597", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GJX9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GJX9" } ], "pmid": "" }, { "name": "neuron differentiation", "id": "GO:0030182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030182", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GJX9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GJX9" } ], "pmid": "" }, { "name": "positive regulation of neural precursor cell proliferation", "id": "GO:2000179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000179", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GJX9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GJX9" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GJX9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GJX9" } ], "pmid": "" }, { "name": "endocrine pancreas development", "id": "GO:0031018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031018", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GJX9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GJX9" } ], "pmid": "" }, { "name": "regulation of protein-containing complex assembly", "id": "GO:0043254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043254", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GJX9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GJX9" } ], "pmid": "" }, { "name": "noradrenergic neuron development", "id": "GO:0003358", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003358", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GJX9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GJX9" } ], "pmid": "" }, { "name": "adrenal chromaffin cell differentiation", "id": "GO:0061104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061104", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GJX9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GJX9" } ], "pmid": "" }, { "name": "sympathetic ganglion development", "id": "GO:0061549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061549", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GJX9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GJX9" } ], "pmid": "" }, { "name": "transdifferentiation", "id": "GO:0060290", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060290", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GJX9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GJX9" } ], "pmid": "" }, { "name": "norepinephrine biosynthetic process", "id": "GO:0042421", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042421", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GJX9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GJX9" } ], "pmid": "" }, { "name": "regulation of cell cycle process", "id": "GO:0010564", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010564", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GJX9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GJX9" } ], "pmid": "" }, { "name": "endocrine system development", "id": "GO:0035270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GJX9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GJX9" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GJX9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GJX9" } ], "pmid": "" }, { "name": "type B pancreatic cell development", "id": "GO:0003323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003323", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GJX9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GJX9" } ], "pmid": "" }, { "name": "type B pancreatic cell differentiation", "id": "GO:0003309", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003309", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GJX9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GJX9" } ], "pmid": "" }, { "name": "pancreatic A cell differentiation", "id": "GO:0003310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003310", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GJX9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GJX9" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GJX9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GJX9" } ], "pmid": "" }, { "name": "transcription repressor complex", "id": "GO:0017053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017053", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GJX9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GJX9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6GJX9-1", "start_pos": "297", "end_pos": "297", "site_lbl": "Thr297", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 297, "start_aa": "Thr", "end_pos": 297, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr297", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6GJX9-1" }, { "uniprot_canonical_ac": "A0A8I6GK09-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GK09", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GK09" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 207, "chemical_mass": 22881.0, "gene_names": "ENSRNOG00000068651", "protein_name": "L-lactate dehydrogenase A chain", "disease": [], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GK09", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GK09" } ], "pmid": "" } ], "molecular_function": [ { "name": "L-lactate dehydrogenase (NAD+) activity", "id": "GO:0004459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004459", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GK09", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GK09" } ], "pmid": "" } ], "biological_process": [ { "name": "lactate metabolic process", "id": "GO:0006089", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006089", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GK09", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GK09" } ], "pmid": "" }, { "name": "pyruvate catabolic process", "id": "GO:0042867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042867", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GK09", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GK09" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6GK09-1" }, { "uniprot_canonical_ac": "A0A8I6GKN0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GKN0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GKN0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 542, "chemical_mass": 61215.0, "gene_names": "Ankub1;Ankub1", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6GKN0-1" }, { "uniprot_canonical_ac": "A0A8I6GKR8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GKR8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GKR8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 132, "chemical_mass": 14543.0, "gene_names": "Rps12l12;Rps12l12;Rps12l3;Rps12l5", "protein_name": "40S ribosomal protein S12", "disease": [], "biological_process": [ { "name": "maintenance of translational fidelity", "id": "GO:1990145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990145", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GKR8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GKR8" } ], "pmid": "" }, { "name": "ribosomal small subunit biogenesis", "id": "GO:0042274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042274", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GKR8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GKR8" } ], "pmid": "" } ], "molecular_function": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GKR8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GKR8" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosolic small ribosomal subunit", "id": "GO:0022627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022627", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GKR8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GKR8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6GKR8-1" }, { "uniprot_canonical_ac": "A0A8I6GKU5-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GKU5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GKU5" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 152, "chemical_mass": 17610.0, "gene_names": "ENSRNOG00000062839", "protein_name": "AP complex subunit sigma", "disease": [], "cellular_component": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GKU5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GKU5" } ], "pmid": "" }, { "name": "cytoplasmic vesicle membrane", "id": "GO:0030659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030659", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GKU5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GKU5" } ], "pmid": "" }, { "name": "AP-3 adaptor complex", "id": "GO:0030123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030123", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GKU5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GKU5" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GKU5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GKU5" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GKU5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GKU5" } ], "pmid": "" }, { "name": "Golgi to vacuole transport", "id": "GO:0006896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006896", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GKU5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GKU5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6GKU5-1" }, { "uniprot_canonical_ac": "A0A8I6GKZ0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GKZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GKZ0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 298, "chemical_mass": 33543.0, "gene_names": "Gstt3", "protein_name": "glutathione transferase", "disease": [], "molecular_function": [ { "name": "glutathione transferase activity", "id": "GO:0004364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004364", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GKZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GKZ0" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GKZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GKZ0" } ], "pmid": "" } ], "biological_process": [ { "name": "glutathione metabolic process", "id": "GO:0006749", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006749", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GKZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GKZ0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6GKZ0-1" }, { "uniprot_canonical_ac": "A0A8I6GL13-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GL13", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GL13" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 2247, "chemical_mass": 247693.0, "gene_names": "Lrpl1;LOC100910088", "protein_name": "", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GL13", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GL13" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GL13", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GL13" } ], "pmid": "" } ], "biological_process": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GL13", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GL13" } ], "pmid": "" } ], "molecular_function": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GL13", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GL13" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6GL13-1" }, { "uniprot_canonical_ac": "A0A8I6GL87-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GL87", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GL87" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 237, "chemical_mass": 26137.0, "gene_names": "Pebp4", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6GL87-1", "start_pos": "157", "end_pos": "157", "site_lbl": "Thr157", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 157, "start_aa": "Thr", "end_pos": 157, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr157", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I6GL87-1", "start_pos": "161", "end_pos": "161", "site_lbl": "Thr161", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 161, "start_aa": "Thr", "end_pos": 161, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr161", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6GL87-1" }, { "uniprot_canonical_ac": "A0A8I6GLY6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GLY6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GLY6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 635, "chemical_mass": 70009.0, "gene_names": "Gga1;Gga1", "protein_name": "", "disease": [ { "disease_id": "DOID:1289", "name": "neurodegenerative disease", "description": "A central nervous system disease that results in the progressive deterioration of function or structure of neurons.", "url": "https://disease-ontology.org/term/DOID:1289", "evidence": [ { "id": "1289", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1289" } ], "weight": 0.0 }, { "disease_id": "DOID:3211", "name": "lysosomal storage disease", "description": "An inherited metabolic disorder that involve an abnormal accumulation of substances inside the lysosome resulting from defects in lysosomal function.", "url": "https://disease-ontology.org/term/DOID:3211", "evidence": [ { "id": "3211", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3211" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GLY6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GLY6" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GLY6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GLY6" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GLY6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GLY6" } ], "pmid": "" }, { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GLY6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GLY6" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GLY6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GLY6" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GLY6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GLY6" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GLY6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GLY6" } ], "pmid": "" }, { "name": "intracellular protein localization", "id": "GO:0008104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008104", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GLY6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GLY6" } ], "pmid": "" }, { "name": "Golgi to plasma membrane protein transport", "id": "GO:0043001", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043001", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GLY6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GLY6" } ], "pmid": "" }, { "name": "positive regulation of protein catabolic process", "id": "GO:0045732", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045732", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GLY6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GLY6" } ], "pmid": "" }, { "name": "retrograde transport, endosome to Golgi", "id": "GO:0042147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042147", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GLY6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GLY6" } ], "pmid": "" }, { "name": "protein localization to cell surface", "id": "GO:0034394", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034394", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GLY6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GLY6" } ], "pmid": "" }, { "name": "Golgi to plasma membrane transport", "id": "GO:0006893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006893", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GLY6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GLY6" } ], "pmid": "" }, { "name": "protein localization to ciliary membrane", "id": "GO:1903441", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903441", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GLY6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GLY6" } ], "pmid": "" }, { "name": "protein localization to cell periphery", "id": "GO:1990778", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990778", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GLY6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GLY6" } ], "pmid": "" }, { "name": "protein localization to membrane", "id": "GO:0072657", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072657", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GLY6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GLY6" } ], "pmid": "" } ], "molecular_function": [ { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GLY6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GLY6" } ], "pmid": "" }, { "name": "phosphatidylinositol binding", "id": "GO:0035091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035091", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GLY6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GLY6" } ], "pmid": "" }, { "name": "ubiquitin binding", "id": "GO:0043130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043130", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GLY6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GLY6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6GLY6-1" }, { "uniprot_canonical_ac": "A0A8J8XQ12-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8J8XQ12", "url": "https://www.uniprot.org/uniprotkb/A0A8J8XQ12" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 639, "chemical_mass": 70688.0, "gene_names": "Wdr46", "protein_name": "WD repeat-containing protein 46", "disease": [ { "disease_id": "DOID:13359", "name": "Ehlers-Danlos syndrome", "description": "A collagen disease that is characterized by extremely flexible joints, elastic skin, and excessive bruising caused by a heritable defect in collagen synthesis, which leads to marked healing difficulties. EDS has five cardinal signs, which may be present to some degree in all of the subtypes. These five cardinal signs are skin fragility, blood vessel fragility, skin hyperelasticity, joint hypermobility, and characteristic subcutaneous nodules.", "url": "https://disease-ontology.org/term/DOID:13359", "evidence": [ { "id": "13359", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13359" } ], "weight": 0.0 }, { "disease_id": "DOID:14720", "name": "Ehlers-Danlos syndrome classic type 1", "description": "An Ehlers-Danlos syndrome that is characterized by loose-jointedness and fragile, bruisable skin that heals with peculiar 'cigarette-paper' scars and that has_material_basis_in heterozygous mutation in the collagen alpha-1(V) gene (COL5A1) on chromosome 9q34.", "url": "https://disease-ontology.org/term/DOID:14720", "evidence": [ { "id": "14720", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14720" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8J8XQ12", "url": "https://www.uniprot.org/uniprotkb/A0A8J8XQ12" } ], "pmid": "" }, { "name": "small-subunit processome", "id": "GO:0032040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032040", "evidence": [ { "database": "UniProtKB", "id": "A0A8J8XQ12", "url": "https://www.uniprot.org/uniprotkb/A0A8J8XQ12" } ], "pmid": "" } ], "biological_process": [ { "name": "ribosomal small subunit biogenesis", "id": "GO:0042274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042274", "evidence": [ { "database": "UniProtKB", "id": "A0A8J8XQ12", "url": "https://www.uniprot.org/uniprotkb/A0A8J8XQ12" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8J8XQ12-1" }, { "uniprot_canonical_ac": "A0A8L2QHS0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8L2QHS0", "url": "https://www.uniprot.org/uniprotkb/A0A8L2QHS0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 960, "chemical_mass": 103395.0, "gene_names": "Rasip1;Rasip1", "protein_name": "Ras-interacting protein 1", "disease": [], "biological_process": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8L2QHS0", "url": "https://www.uniprot.org/uniprotkb/A0A8L2QHS0" } ], "pmid": "" }, { "name": "negative regulation of Rho-dependent protein serine/threonine kinase activity", "id": "GO:2000299", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000299", "evidence": [ { "database": "UniProtKB", "id": "A0A8L2QHS0", "url": "https://www.uniprot.org/uniprotkb/A0A8L2QHS0" } ], "pmid": "" }, { "name": "angiogenesis", "id": "GO:0001525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001525", "evidence": [ { "database": "UniProtKB", "id": "A0A8L2QHS0", "url": "https://www.uniprot.org/uniprotkb/A0A8L2QHS0" } ], "pmid": "" }, { "name": "vasculogenesis", "id": "GO:0001570", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001570", "evidence": [ { "database": "UniProtKB", "id": "A0A8L2QHS0", "url": "https://www.uniprot.org/uniprotkb/A0A8L2QHS0" } ], "pmid": "" }, { "name": "negative regulation of autophagy", "id": "GO:0010507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010507", "evidence": [ { "database": "UniProtKB", "id": "A0A8L2QHS0", "url": "https://www.uniprot.org/uniprotkb/A0A8L2QHS0" } ], "pmid": "" }, { "name": "negative regulation of Rho protein signal transduction", "id": "GO:0035024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035024", "evidence": [ { "database": "UniProtKB", "id": "A0A8L2QHS0", "url": "https://www.uniprot.org/uniprotkb/A0A8L2QHS0" } ], "pmid": "" }, { "name": "positive regulation of integrin activation", "id": "GO:0033625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033625", "evidence": [ { "database": "UniProtKB", "id": "A0A8L2QHS0", "url": "https://www.uniprot.org/uniprotkb/A0A8L2QHS0" } ], "pmid": "" }, { "name": "branching morphogenesis of an epithelial tube", "id": "GO:0048754", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048754", "evidence": [ { "database": "UniProtKB", "id": "A0A8L2QHS0", "url": "https://www.uniprot.org/uniprotkb/A0A8L2QHS0" } ], "pmid": "" }, { "name": "negative regulation of membrane permeability", "id": "GO:1905709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905709", "evidence": [ { "database": "UniProtKB", "id": "A0A8L2QHS0", "url": "https://www.uniprot.org/uniprotkb/A0A8L2QHS0" } ], "pmid": "" } ], "cellular_component": [ { "name": "cell-cell junction", "id": "GO:0005911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005911", "evidence": [ { "database": "UniProtKB", "id": "A0A8L2QHS0", "url": "https://www.uniprot.org/uniprotkb/A0A8L2QHS0" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A8L2QHS0", "url": "https://www.uniprot.org/uniprotkb/A0A8L2QHS0" } ], "pmid": "" }, { "name": "Golgi stack", "id": "GO:0005795", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005795", "evidence": [ { "database": "UniProtKB", "id": "A0A8L2QHS0", "url": "https://www.uniprot.org/uniprotkb/A0A8L2QHS0" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A8L2QHS0", "url": "https://www.uniprot.org/uniprotkb/A0A8L2QHS0" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A8L2QHS0", "url": "https://www.uniprot.org/uniprotkb/A0A8L2QHS0" } ], "pmid": "" }, { "name": "GTPase binding", "id": "GO:0051020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051020", "evidence": [ { "database": "UniProtKB", "id": "A0A8L2QHS0", "url": "https://www.uniprot.org/uniprotkb/A0A8L2QHS0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8L2QHS0-1", "start_pos": "107", "end_pos": "107", "site_lbl": "Thr107", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 107, "start_aa": "Thr", "end_pos": 107, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr107", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8L2QHS0-1" }, { "uniprot_canonical_ac": "A0A8L2QPJ1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8L2QPJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8L2QPJ1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 44, "chemical_mass": 5042.0, "gene_names": "Tmsb10l2;LOC103693420;Tmsb10l2", "protein_name": "Thymosin beta", "disease": [], "molecular_function": [ { "name": "actin monomer binding", "id": "GO:0003785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003785", "evidence": [ { "database": "UniProtKB", "id": "A0A8L2QPJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8L2QPJ1" } ], "pmid": "" }, { "name": "protein sequestering activity", "id": "GO:0140311", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140311", "evidence": [ { "database": "UniProtKB", "id": "A0A8L2QPJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8L2QPJ1" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8L2QPJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8L2QPJ1" } ], "pmid": "" } ], "biological_process": [ { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "A0A8L2QPJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8L2QPJ1" } ], "pmid": "" }, { "name": "regulation of cell migration", "id": "GO:0030334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030334", "evidence": [ { "database": "UniProtKB", "id": "A0A8L2QPJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8L2QPJ1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8L2QPJ1-1" }, { "uniprot_canonical_ac": "F7EVZ0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F7EVZ0", "url": "https://www.uniprot.org/uniprotkb/F7EVZ0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1736, "chemical_mass": 171504.0, "gene_names": "Col5a3;Col5a3", "protein_name": "", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "F7EVZ0", "url": "https://www.uniprot.org/uniprotkb/F7EVZ0" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "F7EVZ0", "url": "https://www.uniprot.org/uniprotkb/F7EVZ0" } ], "pmid": "" }, { "name": "collagen type V trimer", "id": "GO:0005588", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005588", "evidence": [ { "database": "UniProtKB", "id": "F7EVZ0", "url": "https://www.uniprot.org/uniprotkb/F7EVZ0" } ], "pmid": "" } ], "molecular_function": [ { "name": "heparin binding", "id": "GO:0008201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008201", "evidence": [ { "database": "UniProtKB", "id": "F7EVZ0", "url": "https://www.uniprot.org/uniprotkb/F7EVZ0" } ], "pmid": "" }, { "name": "proteoglycan binding", "id": "GO:0043394", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043394", "evidence": [ { "database": "UniProtKB", "id": "F7EVZ0", "url": "https://www.uniprot.org/uniprotkb/F7EVZ0" } ], "pmid": "" }, { "name": "extracellular matrix structural constituent conferring tensile strength", "id": "GO:0030020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030020", "evidence": [ { "database": "UniProtKB", "id": "F7EVZ0", "url": "https://www.uniprot.org/uniprotkb/F7EVZ0" } ], "pmid": "" } ], "biological_process": [ { "name": "cell-matrix adhesion", "id": "GO:0007160", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007160", "evidence": [ { "database": "UniProtKB", "id": "F7EVZ0", "url": "https://www.uniprot.org/uniprotkb/F7EVZ0" } ], "pmid": "" }, { "name": "collagen fibril organization", "id": "GO:0030199", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030199", "evidence": [ { "database": "UniProtKB", "id": "F7EVZ0", "url": "https://www.uniprot.org/uniprotkb/F7EVZ0" } ], "pmid": "" }, { "name": "skeletal system morphogenesis", "id": "GO:0048705", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048705", "evidence": [ { "database": "UniProtKB", "id": "F7EVZ0", "url": "https://www.uniprot.org/uniprotkb/F7EVZ0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "F7EVZ0-1", "start_pos": "274", "end_pos": "274", "site_lbl": "Thr274", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 274, "start_aa": "Thr", "end_pos": 274, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr274", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "F7EVZ0-1", "start_pos": "301", "end_pos": "301", "site_lbl": "Thr301", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 301, "start_aa": "Thr", "end_pos": 301, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr301", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "F7EVZ0-1", "start_pos": "346", "end_pos": "346", "site_lbl": "Thr346", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 346, "start_aa": "Thr", "end_pos": 346, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr346", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "F7EVZ0-1", "start_pos": "588", "end_pos": "588", "site_lbl": "Thr588", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 588, "start_aa": "Thr", "end_pos": 588, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr588", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "F7EVZ0-1" }, { "uniprot_canonical_ac": "F7EYK8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F7EYK8", "url": "https://www.uniprot.org/uniprotkb/F7EYK8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 678, "chemical_mass": 72990.0, "gene_names": "Ubqln3;Ubqln3", "protein_name": "Ubiquilin-3", "disease": [ { "disease_id": "DOID:332", "name": "amyotrophic lateral sclerosis", "description": "A motor neuron disease that is characterized by muscle spasticity, rapidly progressive weakness due to muscle atrophy, difficulty in speaking, swallowing, and breathing.", "url": "https://disease-ontology.org/term/DOID:332", "evidence": [ { "id": "332", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:332" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F7EYK8", "url": "https://www.uniprot.org/uniprotkb/F7EYK8" } ], "pmid": "" } ], "molecular_function": [ { "name": "polyubiquitin modification-dependent protein binding", "id": "GO:0031593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031593", "evidence": [ { "database": "UniProtKB", "id": "F7EYK8", "url": "https://www.uniprot.org/uniprotkb/F7EYK8" } ], "pmid": "" } ], "biological_process": [ { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "F7EYK8", "url": "https://www.uniprot.org/uniprotkb/F7EYK8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "F7EYK8-1", "start_pos": "132", "end_pos": "132", "site_lbl": "Thr132", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 132, "start_aa": "Thr", "end_pos": 132, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr132", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "F7EYK8-1", "start_pos": "389", "end_pos": "389", "site_lbl": "Thr389", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 389, "start_aa": "Thr", "end_pos": 389, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr389", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "F7EYK8-1", "start_pos": "483", "end_pos": "483", "site_lbl": "Thr483", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 483, "start_aa": "Thr", "end_pos": 483, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr483", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "F7EYK8-1", "start_pos": "491", "end_pos": "491", "site_lbl": "Thr491", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 491, "start_aa": "Thr", "end_pos": 491, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr491", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "F7EYK8-1", "start_pos": "597", "end_pos": "597", "site_lbl": "Thr597", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 597, "start_aa": "Thr", "end_pos": 597, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr597", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "F7EYK8-1" }, { "uniprot_canonical_ac": "F7F9Q8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F7F9Q8", "url": "https://www.uniprot.org/uniprotkb/F7F9Q8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 210, "chemical_mass": 23800.0, "gene_names": "Calml4", "protein_name": "Calmodulin-like protein 4", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F7F9Q8", "url": "https://www.uniprot.org/uniprotkb/F7F9Q8" } ], "pmid": "" }, { "name": "microvillus", "id": "GO:0005902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005902", "evidence": [ { "database": "UniProtKB", "id": "F7F9Q8", "url": "https://www.uniprot.org/uniprotkb/F7F9Q8" } ], "pmid": "" } ], "molecular_function": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "F7F9Q8", "url": "https://www.uniprot.org/uniprotkb/F7F9Q8" } ], "pmid": "" }, { "name": "enzyme regulator activity", "id": "GO:0030234", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030234", "evidence": [ { "database": "UniProtKB", "id": "F7F9Q8", "url": "https://www.uniprot.org/uniprotkb/F7F9Q8" } ], "pmid": "" }, { "name": "myosin head/neck binding", "id": "GO:0032028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032028", "evidence": [ { "database": "UniProtKB", "id": "F7F9Q8", "url": "https://www.uniprot.org/uniprotkb/F7F9Q8" } ], "pmid": "" } ], "biological_process": [ { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "F7F9Q8", "url": "https://www.uniprot.org/uniprotkb/F7F9Q8" } ], "pmid": "" }, { "name": "brush border assembly", "id": "GO:1904970", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904970", "evidence": [ { "database": "UniProtKB", "id": "F7F9Q8", "url": "https://www.uniprot.org/uniprotkb/F7F9Q8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "F7F9Q8-1", "start_pos": "102", "end_pos": "102", "site_lbl": "Thr102", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 102, "start_aa": "Thr", "end_pos": 102, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr102", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "F7F9Q8-1" }, { "uniprot_canonical_ac": "F7FLA1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F7FLA1", "url": "https://www.uniprot.org/uniprotkb/F7FLA1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 432, "chemical_mass": 47385.0, "gene_names": "Slc35b2", "protein_name": "Adenosine 3'-phospho 5'-phosphosulfate transporter 1", "disease": [ { "disease_id": "DOID:0070403", "name": "hypomyelinating leukodystrophy 26", "description": "A hypomyelinating leukodystrophy characterized by severe psychomotor delay, predominantly involving motor and expressive language development, cerebral and cerebellar atrophy, and corpus callosum hypoplasia that has_material_basis_in homozygous mutation in the SLC35B2 gene on chromosome 6p21.", "url": "https://disease-ontology.org/term/DOID:0070403", "evidence": [ { "id": "0070403", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070403" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "F7FLA1", "url": "https://www.uniprot.org/uniprotkb/F7FLA1" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "F7FLA1", "url": "https://www.uniprot.org/uniprotkb/F7FLA1" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F7FLA1", "url": "https://www.uniprot.org/uniprotkb/F7FLA1" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "F7FLA1", "url": "https://www.uniprot.org/uniprotkb/F7FLA1" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "F7FLA1", "url": "https://www.uniprot.org/uniprotkb/F7FLA1" } ], "pmid": "" } ], "biological_process": [ { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "F7FLA1", "url": "https://www.uniprot.org/uniprotkb/F7FLA1" } ], "pmid": "" }, { "name": "chondroitin sulfate proteoglycan biosynthetic process", "id": "GO:0050650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050650", "evidence": [ { "database": "UniProtKB", "id": "F7FLA1", "url": "https://www.uniprot.org/uniprotkb/F7FLA1" } ], "pmid": "" }, { "name": "3'-phosphoadenosine 5'-phosphosulfate transport", "id": "GO:0046963", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046963", "evidence": [ { "database": "UniProtKB", "id": "F7FLA1", "url": "https://www.uniprot.org/uniprotkb/F7FLA1" } ], "pmid": "" }, { "name": "peptidyl-tyrosine sulfation", "id": "GO:0006478", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006478", "evidence": [ { "database": "UniProtKB", "id": "F7FLA1", "url": "https://www.uniprot.org/uniprotkb/F7FLA1" } ], "pmid": "" }, { "name": "5'-adenylyl sulfate transmembrane transport", "id": "GO:1902558", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902558", "evidence": [ { "database": "UniProtKB", "id": "F7FLA1", "url": "https://www.uniprot.org/uniprotkb/F7FLA1" } ], "pmid": "" } ], "molecular_function": [ { "name": "3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity", "id": "GO:0046964", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046964", "evidence": [ { "database": "UniProtKB", "id": "F7FLA1", "url": "https://www.uniprot.org/uniprotkb/F7FLA1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "F7FLA1-1", "start_pos": "105", "end_pos": "105", "site_lbl": "Thr105", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 105, "start_aa": "Thr", "end_pos": 105, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr105", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "F7FLA1-1" }, { "uniprot_canonical_ac": "M0R3T3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "M0R3T3", "url": "https://www.uniprot.org/uniprotkb/M0R3T3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 230, "chemical_mass": 25411.0, "gene_names": "ENSRNOG00000067174;Klk5l1", "protein_name": "Peptidase S1 domain-containing protein", "disease": [], "molecular_function": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "M0R3T3", "url": "https://www.uniprot.org/uniprotkb/M0R3T3" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "M0R3T3", "url": "https://www.uniprot.org/uniprotkb/M0R3T3" } ], "pmid": "" }, { "name": "secretory granule", "id": "GO:0030141", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030141", "evidence": [ { "database": "UniProtKB", "id": "M0R3T3", "url": "https://www.uniprot.org/uniprotkb/M0R3T3" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of systemic arterial blood pressure", "id": "GO:0003073", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003073", "evidence": [ { "database": "UniProtKB", "id": "M0R3T3", "url": "https://www.uniprot.org/uniprotkb/M0R3T3" } ], "pmid": "" }, { "name": "zymogen activation", "id": "GO:0031638", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031638", "evidence": [ { "database": "UniProtKB", "id": "M0R3T3", "url": "https://www.uniprot.org/uniprotkb/M0R3T3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M0R3T3-1" }, { "uniprot_canonical_ac": "M0R9N3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "M0R9N3", "url": "https://www.uniprot.org/uniprotkb/M0R9N3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 234, "chemical_mass": 26089.0, "gene_names": "Ceacam9", "protein_name": "", "disease": [], "biological_process": [ { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "M0R9N3", "url": "https://www.uniprot.org/uniprotkb/M0R9N3" } ], "pmid": "" }, { "name": "T cell activation", "id": "GO:0042110", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042110", "evidence": [ { "database": "UniProtKB", "id": "M0R9N3", "url": "https://www.uniprot.org/uniprotkb/M0R9N3" } ], "pmid": "" } ], "cellular_component": [ { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "M0R9N3", "url": "https://www.uniprot.org/uniprotkb/M0R9N3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M0R9N3-1" }, { "uniprot_canonical_ac": "A0A0G2JY80-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JY80", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JY80" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 527, "chemical_mass": 56802.0, "gene_names": "Tbl1x;RGD1563868;Tbl1x", "protein_name": "", "disease": [ { "disease_id": "DOID:0050155", "name": "sensory system disease", "description": "A nervous system disease which is located in a part of the nervous system responsible for processing sensory information that consists of sensory receptors, neural pathways, and parts of the brain involved in sensory perception. Commonly recognized sensory systems are those for vision, hearing, somatic sensation (touch), taste and olfaction (smell).", "url": "https://disease-ontology.org/term/DOID:0050155", "evidence": [ { "id": "0050155", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050155" } ], "weight": 0.0 }, { "disease_id": "DOID:0111758", "name": "Y-linked deafness 2", "description": "A Y-linked deafness characterized by male-limited bilateral progressive sensorineural hearing loss of variable severity, with onset in the third to fifth decades of life that has_material_basis_in mutation in the TBL1Y gene on chromosome Yp11.2.", "url": "https://disease-ontology.org/term/DOID:0111758", "evidence": [ { "id": "0111758", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111758" } ], "weight": 0.0 }, { "disease_id": "DOID:0111837", "name": "congenital nongoitrous hypothyroidism 8", "description": "A congenital hypothyroidism characterized by relatively mild central hypothyroidism that has_material_basis_in heterozygous or hemizygous mutation in the TBL1X gene on chromosome Xp22.3-p22.2.", "url": "https://disease-ontology.org/term/DOID:0111837", "evidence": [ { "id": "0111837", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111837" } ], "weight": 0.0 } ], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JY80", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JY80" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JY80", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JY80" } ], "pmid": "" }, { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JY80", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JY80" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JY80", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JY80" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JY80", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JY80" } ], "pmid": "" }, { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JY80", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JY80" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JY80", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JY80" } ], "pmid": "" }, { "name": "response to steroid hormone", "id": "GO:0048545", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048545", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JY80", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JY80" } ], "pmid": "" }, { "name": "protein stabilization", "id": "GO:0050821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050821", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JY80", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JY80" } ], "pmid": "" }, { "name": "fat cell differentiation", "id": "GO:0045444", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045444", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JY80", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JY80" } ], "pmid": "" }, { "name": "sensory perception of sound", "id": "GO:0007605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007605", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JY80", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JY80" } ], "pmid": "" }, { "name": "response to estrogen", "id": "GO:0043627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043627", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JY80", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JY80" } ], "pmid": "" }, { "name": "positive regulation of canonical Wnt signaling pathway", "id": "GO:0090263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090263", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JY80", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JY80" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JY80", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JY80" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JY80", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JY80" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JY80", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JY80" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JY80", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JY80" } ], "pmid": "" }, { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JY80", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JY80" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JY80", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JY80" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JY80", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JY80" } ], "pmid": "" }, { "name": "transcription repressor complex", "id": "GO:0017053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017053", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JY80", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JY80" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JY80", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JY80" } ], "pmid": "" }, { "name": "histone deacetylase complex", "id": "GO:0000118", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000118", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JY80", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JY80" } ], "pmid": "" }, { "name": "mitotic spindle", "id": "GO:0072686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072686", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JY80", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JY80" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A0G2JY80-1" }, { "uniprot_canonical_ac": "A0A8I5YCM0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YCM0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YCM0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 323, "chemical_mass": 36007.0, "gene_names": "Or5p58;Or5p58;RGD1562400", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YCM0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YCM0" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YCM0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YCM0" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YCM0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YCM0" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YCM0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YCM0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5YCM0-1" }, { "uniprot_canonical_ac": "A0A8I5ZMG7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMG7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMG7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 568, "chemical_mass": 66270.0, "gene_names": "Zfp950l16;LOC102549410", "protein_name": "", "disease": [], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMG7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMG7" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMG7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMG7" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMG7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMG7" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMG7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMG7" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMG7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMG7" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMG7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMG7" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMG7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMG7" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMG7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMG7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZMG7-1" }, { "uniprot_canonical_ac": "A0A8I5ZMP3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMP3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMP3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 437, "chemical_mass": 49080.0, "gene_names": "ENSRNOG00000069209;RT1-A1", "protein_name": "", "disease": [ { "disease_id": "DOID:0050426", "name": "Stevens-Johnson syndrome", "description": "A skin disease that is characterized by ulceration of less than 10 percent of the surface area of the body. The disease is often precipitated by the use of medications, such as antibiotics or antiepileptics, or onset of infection.", "url": "https://disease-ontology.org/term/DOID:0050426", "evidence": [ { "id": "0050426", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050426" } ], "weight": 0.0 }, { "disease_id": "DOID:0060180", "name": "colitis", "description": "An inflammatory bowel disease that involves inflammation located_in colon.", "url": "https://disease-ontology.org/term/DOID:0060180", "evidence": [ { "id": "0060180", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060180" } ], "weight": 0.0 }, { "disease_id": "DOID:0080160", "name": "Cytomegalovirus retinitis", "description": "A retinitis that has_material_basis_in Cytomegalovirus.", "url": "https://disease-ontology.org/term/DOID:0080160", "evidence": [ { "id": "0080160", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080160" } ], "weight": 0.0 }, { "disease_id": "DOID:0080600", "name": "COVID-19", "description": "A Coronavirus infectious disease that is characterized by fever, cough and shortness of breath and that has_material_basis_in Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a subtype of Betacoronavirus pandemicum.", "url": "https://disease-ontology.org/term/DOID:0080600", "evidence": [ { "id": "0080600", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080600" } ], "weight": 0.0 }, { "disease_id": "DOID:0080603", "name": "ankylosing spondylitis 1", "description": "A ankylosing spondylitis that has_material_basis_in variation in the HLA-B27 allele on chromosome 6p21.3.", "url": "https://disease-ontology.org/term/DOID:0080603", "evidence": [ { "id": "0080603", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080603" } ], "weight": 0.0 }, { "disease_id": "DOID:0080750", "name": "erythema nodosum", "description": "A panniculitis that is characterized by sudden onset of painful, erythematous, subcutaneous nodules mainly localized to the pretibial areas. Lesions are usually bilateral and symmetrical, ranging from 1 to 5 cm in diameter.", "url": "https://disease-ontology.org/term/DOID:0080750", "evidence": [ { "id": "0080750", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080750" } ], "weight": 0.0 }, { "disease_id": "DOID:0080820", "name": "occupational asthma", "description": "An environmental induced asthma that is characterized by a variable airflow limitation due to exposure to inhaled irritants in the workplace.", "url": "https://disease-ontology.org/term/DOID:0080820", "evidence": [ { "id": "0080820", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080820" } ], "weight": 0.0 }, { "disease_id": "DOID:0081267", "name": "graft-versus-host disease", "description": "An immune system disease that is characterized by recognition by mature donor T cells, that contaminate the allogeneic bone marrow, of the recipient's tissue as foreign, causing a severe inflammatory disease characterized by rashes, diarrhea, and liver disease, and that has_material_basis_in an associated with variation in the interleukin-10 gene (IL10) on chromosome 1q32.", "url": "https://disease-ontology.org/term/DOID:0081267", "evidence": [ { "id": "0081267", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081267" } ], "weight": 0.0 }, { "disease_id": "DOID:0111079", "name": "birdshot chorioretinopathy", "description": "A posterior uveitis characterized by multiple small, hypopigmented, cream-colored choroidal lesions scattered symmetrically in the fundus primarily around the optic disc that presents in patients as blurred vision, floaters, photopsia, scotoma and nyctalopia.", "url": "https://disease-ontology.org/term/DOID:0111079", "evidence": [ { "id": "0111079", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111079" } ], "weight": 0.0 }, { "disease_id": "DOID:0111286", "name": "psoriasis 1", "description": "A psoriasis that has_material_basis_in variation in the HLA-C gene on chromosome 6p21.33.", "url": "https://disease-ontology.org/term/DOID:0111286", "evidence": [ { "id": "0111286", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111286" } ], "weight": 0.0 }, { "disease_id": "DOID:10003", "name": "sensorineural hearing loss", "description": "An inner ear disease that is characterized by hearing loss resulting from damage to the cochlea, auditory nerve and/or brainstem.", "url": "https://disease-ontology.org/term/DOID:10003", "evidence": [ { "id": "10003", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10003" } ], "weight": 0.0 }, { "disease_id": "DOID:1123", "name": "spondyloarthropathy", "description": "", "url": "https://disease-ontology.org/term/DOID:1123", "evidence": [ { "id": "1123", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1123" } ], "weight": 0.0 }, { "disease_id": "DOID:11265", "name": "trachoma", "description": "A commensal bacterial infectious disease that results_in infection located_in eye, has_material_basis_in Chlamydia trachomatis (A, B, Ba and C serovars), which is transmitted_by contact with eye discharge from the infected person and transmitted_by congenital method. The infection causes eyelid to turn inward which makes eyelashes to scratch the cornea.", "url": "https://disease-ontology.org/term/DOID:11265", "evidence": [ { "id": "11265", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11265" } ], "weight": 0.0 }, { "disease_id": "DOID:11335", "name": "sarcoidosis", "description": "A hypersensitivity reaction type IV disease characterized by the growth of collections of inflammatory cells (granulomas) in multiple organs.", "url": "https://disease-ontology.org/term/DOID:11335", "evidence": [ { "id": "11335", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11335" } ], "weight": 0.0 }, { "disease_id": "DOID:11563", "name": "retinal vasculitis", "description": "A vasculitis that is characterized by inflammation of the vascular branches of the retinal artery and has_symptom painless decrease of visual acuity, visual floaters, dark spot in vision, decreased ability to distinguish colors, and distortion of images such as linear images.", "url": "https://disease-ontology.org/term/DOID:11563", "evidence": [ { "id": "11563", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11563" } ], "weight": 0.0 }, { "disease_id": "DOID:12185", "name": "otosclerosis", "description": "An otitis interna characterized by isolated endochondral bone sclerosis of the labyrinthine capsule.", "url": "https://disease-ontology.org/term/DOID:12185", "evidence": [ { "id": "12185", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12185" } ], "weight": 0.0 }, { "disease_id": "DOID:12361", "name": "Graves' disease", "description": "An autoimmune disease of endocrine system that involves production of excessive amount of thyroid hormones, located_in thyroid gland.", "url": "https://disease-ontology.org/term/DOID:12361", "evidence": [ { "id": "12361", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12361" } ], "weight": 0.0 }, { "disease_id": "DOID:1273", "name": "respiratory syncytial virus infectious disease", "description": "A viral infectious disease that results_in infection located_in upper respiratory tract or located_in lower respiratory tract, has_material_basis_in Human respiratory syncytial virus (Orthopneumovirus hominis), which is transmitted_by droplet spread of nasal secretions from an infected person while coughing or sneezing, or transmitted_by contaminated fomites. The infection has_symptom runny nose, has_symptom fever, has_symptom cough, has_symptom wheezing, and has_symptom respiratory distress.", "url": "https://disease-ontology.org/term/DOID:1273", "evidence": [ { "id": "1273", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1273" } ], "weight": 0.0 }, { "disease_id": "DOID:13025", "name": "retinopathy of prematurity", "description": "", "url": "https://disease-ontology.org/term/DOID:13025", "evidence": [ { "id": "13025", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13025" } ], "weight": 0.0 }, { "disease_id": "DOID:13141", "name": "uveitis", "description": "An uveal disease is characterized by inflammation of any of the layers of the uvea of the eye, which includes the iris, ciliary body, and choroid.", "url": "https://disease-ontology.org/term/DOID:13141", "evidence": [ { "id": "13141", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13141" } ], "weight": 0.0 }, { "disease_id": "DOID:13241", "name": "Behcet's disease", "description": "An autoimmune disease that is characterized by mucocutaneous manifestations, including recurrent oral and genital ulcerations, ocular manifestations, especially chronic relapsing uveitis, and systemic vasculitis involving arteries and veins of all sizes.", "url": "https://disease-ontology.org/term/DOID:13241", "evidence": [ { "id": "13241", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13241" } ], "weight": 0.0 }, { "disease_id": "DOID:1407", "name": "anterior uveitis", "description": "", "url": "https://disease-ontology.org/term/DOID:1407", "evidence": [ { "id": "1407", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1407" } ], "weight": 0.0 }, { "disease_id": "DOID:1485", "name": "cystic fibrosis", "description": "A syndrome that is characterized by the buildup of thick, sticky mucus that can damage many organs.", "url": "https://disease-ontology.org/term/DOID:1485", "evidence": [ { "id": "1485", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1485" } ], "weight": 0.0 }, { "disease_id": "DOID:1883", "name": "hepatitis C", "description": "A viral hepatitis that results_in inflammation located_in liver, has_material_basis_in hepatitis C virus (Hepacivirus hominis), which is transmitted_by blood from an infected person enters the body of an uninfected person. The infection has_symptom fever, has_symptom fatigue, has_symptom loss of appetite, has_symptom nausea, has_symptom vomiting, has_symptom abdominal pain, has_symptom clay-colored bowel movements, has_symptom joint pain, and has_symptom jaundice.", "url": "https://disease-ontology.org/term/DOID:1883", "evidence": [ { "id": "1883", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1883" } ], "weight": 0.0 }, { "disease_id": "DOID:2508", "name": "Takayasu's arteritis", "description": "A vasculitis that involves inflammation of the aorta that carries blood from the heart to the rest of the body.", "url": "https://disease-ontology.org/term/DOID:2508", "evidence": [ { "id": "2508", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2508" } ], "weight": 0.0 }, { "disease_id": "DOID:2703", "name": "synovitis", "description": "A connective tissue disease that results_in inflammation located_in synovial membrane that lines a synovial joint which causes pain and swelling.", "url": "https://disease-ontology.org/term/DOID:2703", "evidence": [ { "id": "2703", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2703" } ], "weight": 0.0 }, { "disease_id": "DOID:2723", "name": "dermatitis", "description": "A skin disease characterized by itchy, erythematous, vesicular, weeping and crusting patches of skin.", "url": "https://disease-ontology.org/term/DOID:2723", "evidence": [ { "id": "2723", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2723" } ], "weight": 0.0 }, { "disease_id": "DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.", "url": "https://disease-ontology.org/term/DOID:2841", "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ], "weight": 0.0 }, { "disease_id": "DOID:2945", "name": "severe acute respiratory syndrome", "description": "A Coronavirus infectious disease that results_in infection located_in respiratory tract, has_material_basis_in Severe acute respiratory syndrome coronavirus (SARS-CoV or SARS-CoV-1), a subtype of Betacoronavirus pandemicum, which is transmitted_by droplet spread of respiratory secretions, transmitted_by ingestion of contaminated food, or transmitted_by fomites. The infection has_symptom fever, has_symptom headache, has_symptom body aches, has_symptom dry cough, and has_symptom hypoxia.", "url": "https://disease-ontology.org/term/DOID:2945", "evidence": [ { "id": "2945", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2945" } ], "weight": 0.0 }, { "disease_id": "DOID:3526", "name": "cerebral infarction", "description": "A cerebrovascular disease that is characterized by an area of necrotic tissue in the brain resulting from a blockage or narrowing in the arteries supplying blood and oxygen to the brain.", "url": "https://disease-ontology.org/term/DOID:3526", "evidence": [ { "id": "3526", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3526" } ], "weight": 0.0 }, { "disease_id": "DOID:3611", "name": "acute retinal necrosis syndrome", "description": "", "url": "https://disease-ontology.org/term/DOID:3611", "evidence": [ { "id": "3611", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3611" } ], "weight": 0.0 }, { "disease_id": "DOID:3875", "name": "thrombophlebitis", "description": "A phlebitis that results from a blood clot in the vessel.", "url": "https://disease-ontology.org/term/DOID:3875", "evidence": [ { "id": "3875", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3875" } ], "weight": 0.0 }, { "disease_id": "DOID:399", "name": "tuberculosis", "description": "A primary bacterial infectious disease that is located_in lungs, located_in lymph nodes, located_in pericardium, located_in brain, located_in pleura or located_in gastrointestinal tract, has_material_basis_in Mycobacterium tuberculosis, which is transmitted_by droplets released into the air when an infected person coughs or sneezes.", "url": "https://disease-ontology.org/term/DOID:399", "evidence": [ { "id": "399", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:399" } ], "weight": 0.0 }, { "disease_id": "DOID:4362", "name": "cervical cancer", "description": "A female reproductive organ cancer that is located_in the cervix.", "url": "https://disease-ontology.org/term/DOID:4362", "evidence": [ { "id": "4362", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4362" } ], "weight": 0.0 }, { "disease_id": "DOID:4481", "name": "allergic rhinitis", "description": "A rhinitis that is an allergic inflammation and irritation of the nasal airways involving sneezing, runny nose, nasal congestion, itching and tearing of the eyes caused by exposure to an allergen such as pollen, dust, mold, animal dander and droppings of cockroaches or house dust mites.", "url": "https://disease-ontology.org/term/DOID:4481", "evidence": [ { "id": "4481", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4481" } ], "weight": 0.0 }, { "disease_id": "DOID:526", "name": "human immunodeficiency virus infectious disease", "description": "A viral infectious disease that results in destruction of immune system, leading to life-threatening opportunistic infections and cancers, has_material_basis_in Human immunodeficiency virus 1 (Lentivirus humimdef1) or Human immunodeficiency virus 2 (Lentivirus humimdef2), which are transmitted by sexual contact, transmitted by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted by congenital method, and transmitted by contaminated needles. The virus infects helper T cells (CD4+ T cells) which are directly or indirectly destroyed, macrophages, and dendritic cells. The infection has symptom diarrhea, has symptom fatigue, has symptom fever, has symptom vaginal yeast infection, has symptom headache, has symptom mouth sores, has symptom muscle aches, has symptom sore throat, and has symptom swollen lymph glands.", "url": "https://disease-ontology.org/term/DOID:526", "evidence": [ { "id": "526", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:526" } ], "weight": 0.0 }, { "disease_id": "DOID:6039", "name": "uveal melanoma", "description": "A uveal cancer that has_material_basis_in uvea pigment cells.", "url": "https://disease-ontology.org/term/DOID:6039", "evidence": [ { "id": "6039", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6039" } ], "weight": 0.0 }, { "disease_id": "DOID:6196", "name": "reactive arthritis", "description": "An arthritis that is an autoimmune disease which develops due to an infection located elsewhere in the body.", "url": "https://disease-ontology.org/term/DOID:6196", "evidence": [ { "id": "6196", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6196" } ], "weight": 0.0 }, { "disease_id": "DOID:7147", "name": "ankylosing spondylitis", "description": "An arthritis that results_in inflammation in the joints of the spine and pelvis. The disease has_symptom pain, has_symptom stiffness in the spine, has_symptom stiffness in the neck, has_symptom stiffness in the hips, has_symptom stiffness in the jaw and has_symptom stiffness in the rib cage.", "url": "https://disease-ontology.org/term/DOID:7147", "evidence": [ { "id": "7147", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7147" } ], "weight": 0.0 }, { "disease_id": "DOID:8947", "name": "diabetic retinopathy", "description": "", "url": "https://disease-ontology.org/term/DOID:8947", "evidence": [ { "id": "8947", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8947" } ], "weight": 0.0 }, { "disease_id": "DOID:9415", "name": "allergic asthma", "description": "An extrinsic asthma that is characterized by symptoms that are triggered by an allergic reaction caused by inhaled allergens such as dust mite allergen, pet dander, pollen and mold. The disease has_symptom coughing, has_symptom wheezing, has_symptom shortness of breath or has_symptom rapid breathing, and has_symptom chest tightness.", "url": "https://disease-ontology.org/term/DOID:9415", "evidence": [ { "id": "9415", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9415" } ], "weight": 0.0 }, { "disease_id": "DOID:9849", "name": "Meniere's disease", "description": "A vestibular disease characterized by vertigo, low-pitched tinnitus and hearing loss.", "url": "https://disease-ontology.org/term/DOID:9849", "evidence": [ { "id": "9849", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9849" } ], "weight": 0.0 }, { "disease_id": "DOID:987", "name": "alopecia", "description": "A hypotrichosis that is characterized by a loss of hair from the head or body.", "url": "https://disease-ontology.org/term/DOID:987", "evidence": [ { "id": "987", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:987" } ], "weight": 0.0 }, { "disease_id": "DOID:988", "name": "mitral valve prolapse", "description": "A mitral valve disease where one or both of the cusps of the mitral valve bulge or collapse backward in the left atrium during systole.", "url": "https://disease-ontology.org/term/DOID:988", "evidence": [ { "id": "988", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:988" } ], "weight": 0.0 } ], "biological_process": [ { "name": "antigen processing and presentation of peptide antigen via MHC class I", "id": "GO:0002474", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002474", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMP3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMP3" } ], "pmid": "" }, { "name": "positive regulation of T cell mediated cytotoxicity", "id": "GO:0001916", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001916", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMP3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMP3" } ], "pmid": "" }, { "name": "negative regulation of natural killer cell mediated cytotoxicity", "id": "GO:0045953", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045953", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMP3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMP3" } ], "pmid": "" }, { "name": "T cell tolerance induction", "id": "GO:0002517", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002517", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMP3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMP3" } ], "pmid": "" }, { "name": "positive regulation of tolerance induction to nonself antigen", "id": "GO:0002657", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002657", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMP3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMP3" } ], "pmid": "" } ], "cellular_component": [ { "name": "phagocytic vesicle membrane", "id": "GO:0030670", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030670", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMP3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMP3" } ], "pmid": "" }, { "name": "MHC class I protein complex", "id": "GO:0042612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042612", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMP3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMP3" } ], "pmid": "" }, { "name": "lumenal side of endoplasmic reticulum membrane", "id": "GO:0098553", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098553", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMP3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMP3" } ], "pmid": "" } ], "molecular_function": [ { "name": "beta-2-microglobulin binding", "id": "GO:0030881", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030881", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMP3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMP3" } ], "pmid": "" }, { "name": "protein-containing complex binding", "id": "GO:0044877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044877", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMP3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMP3" } ], "pmid": "" }, { "name": "peptide binding", "id": "GO:0042277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042277", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZMP3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZMP3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZMP3-1" }, { "uniprot_canonical_ac": "A0A8I5ZN27-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN27", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN27" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1307, "chemical_mass": 147160.0, "gene_names": "Cngb1;CNCG2;CNCG3L;CNCG4;CNG-4;CNG4;Cngb1;Gm1959;RCNC2", "protein_name": "Cyclic nucleotide-gated channel beta-1", "disease": [ { "disease_id": "DOID:0110402", "name": "retinitis pigmentosa 45", "description": "A retinitis pigmentosa that has_material_basis_in mutation in the CNGB1 gene on chromosome 16q13.", "url": "https://disease-ontology.org/term/DOID:0110402", "evidence": [ { "id": "0110402", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110402" } ], "weight": 0.0 }, { "disease_id": "DOID:10584", "name": "retinitis pigmentosa", "description": "A retinal degeneration characterized by the gradual deterioration of the photoreceptors or the retinal pigment epithelium of the retina leading to progressive sight loss.", "url": "https://disease-ontology.org/term/DOID:10584", "evidence": [ { "id": "10584", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10584" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "calcium channel activity", "id": "GO:0005262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005262", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN27", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN27" } ], "pmid": "" }, { "name": "protein-containing complex binding", "id": "GO:0044877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044877", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN27", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN27" } ], "pmid": "" }, { "name": "intracellularly cGMP-activated cation channel activity", "id": "GO:0005223", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005223", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN27", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN27" } ], "pmid": "" }, { "name": "sodium channel activity", "id": "GO:0005272", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005272", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN27", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN27" } ], "pmid": "" }, { "name": "intracellularly cAMP-activated cation channel activity", "id": "GO:0005222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005222", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN27", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN27" } ], "pmid": "" }, { "name": "cAMP binding", "id": "GO:0030552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030552", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN27", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN27" } ], "pmid": "" }, { "name": "cGMP binding", "id": "GO:0030553", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030553", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN27", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN27" } ], "pmid": "" }, { "name": "intracellularly cyclic nucleotide-activated monoatomic cation channel activity", "id": "GO:0005221", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005221", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN27", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN27" } ], "pmid": "" }, { "name": "cyclic nucleotide-activated monoatomic ion channel activity", "id": "GO:0043855", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043855", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN27", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN27" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN27", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN27" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN27", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN27" } ], "pmid": "" }, { "name": "terminal bouton", "id": "GO:0043195", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043195", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN27", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN27" } ], "pmid": "" }, { "name": "photoreceptor outer segment", "id": "GO:0001750", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001750", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN27", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN27" } ], "pmid": "" }, { "name": "intracellular cyclic nucleotide activated cation channel complex", "id": "GO:0017071", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017071", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN27", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN27" } ], "pmid": "" }, { "name": "transmembrane transporter complex", "id": "GO:1902495", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902495", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN27", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN27" } ], "pmid": "" }, { "name": "rod photoreceptor outer segment", "id": "GO:0120200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120200", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN27", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN27" } ], "pmid": "" }, { "name": "non-motile cilium membrane", "id": "GO:0098804", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098804", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN27", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN27" } ], "pmid": "" } ], "biological_process": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN27", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN27" } ], "pmid": "" }, { "name": "positive regulation of gene expression", "id": "GO:0010628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010628", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN27", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN27" } ], "pmid": "" }, { "name": "calcium ion transport", "id": "GO:0006816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006816", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN27", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN27" } ], "pmid": "" }, { "name": "regulation of cytosolic calcium ion concentration", "id": "GO:0051480", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051480", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN27", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN27" } ], "pmid": "" }, { "name": "membrane depolarization", "id": "GO:0051899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051899", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN27", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN27" } ], "pmid": "" }, { "name": "visual perception", "id": "GO:0007601", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007601", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN27", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN27" } ], "pmid": "" }, { "name": "photoreceptor cell maintenance", "id": "GO:0045494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045494", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN27", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN27" } ], "pmid": "" }, { "name": "monoatomic cation transmembrane transport", "id": "GO:0098655", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098655", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN27", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN27" } ], "pmid": "" }, { "name": "retina homeostasis", "id": "GO:0001895", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001895", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN27", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN27" } ], "pmid": "" }, { "name": "monoatomic cation transport", "id": "GO:0006812", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006812", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN27", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN27" } ], "pmid": "" }, { "name": "potassium ion transport", "id": "GO:0006813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006813", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN27", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN27" } ], "pmid": "" }, { "name": "sensory perception of smell", "id": "GO:0007608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007608", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN27", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN27" } ], "pmid": "" }, { "name": "photoreceptor cell outer segment organization", "id": "GO:0035845", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035845", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN27", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN27" } ], "pmid": "" }, { "name": "sodium ion transport", "id": "GO:0006814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006814", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN27", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN27" } ], "pmid": "" }, { "name": "phototransduction", "id": "GO:0007602", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007602", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN27", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN27" } ], "pmid": "" }, { "name": "detection of light stimulus involved in visual perception", "id": "GO:0050908", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050908", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN27", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN27" } ], "pmid": "" }, { "name": "response to odorant", "id": "GO:1990834", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990834", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN27", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN27" } ], "pmid": "" }, { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN27", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN27" } ], "pmid": "" }, { "name": "olfactory nerve maturation", "id": "GO:0021630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021630", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN27", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN27" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I5ZN27-1", "start_pos": "198", "end_pos": "198", "site_lbl": "Thr198", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 198, "start_aa": "Thr", "end_pos": 198, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr198", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I5ZN27-1", "start_pos": "95", "end_pos": "95", "site_lbl": "Thr95", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 95, "start_aa": "Thr", "end_pos": 95, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr95", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I5ZN27-1", "start_pos": "657", "end_pos": "657", "site_lbl": "Ser657", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "E", "comment": "Markedly reduces the affinity of the channel for cAMP.", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN27", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN27" }, { "database": "PubMed", "id": "27405959", "url": "https://glygen.org/publication/PubMed/27405959" } ] } ] } ], "record_id": "A0A8I5ZN27-1" }, { "uniprot_canonical_ac": "A0A8I5ZNW0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNW0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNW0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 124, "chemical_mass": 13514.0, "gene_names": "ENSRNOG00000066577", "protein_name": "Immunoglobulin V-set domain-containing protein", "disease": [], "biological_process": [ { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNW0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNW0" } ], "pmid": "" } ], "cellular_component": [ { "name": "immunoglobulin complex", "id": "GO:0019814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019814", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNW0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNW0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZNW0-1" }, { "uniprot_canonical_ac": "A0A8I5ZRJ5-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZRJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZRJ5" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 225, "chemical_mass": 25311.0, "gene_names": "Arhgdig;Arhgdig", "protein_name": "Rho GDP-dissociation inhibitor 3", "disease": [], "molecular_function": [ { "name": "Rho GDP-dissociation inhibitor activity", "id": "GO:0005094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005094", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZRJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZRJ5" } ], "pmid": "" }, { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZRJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZRJ5" } ], "pmid": "" }, { "name": "GTPase regulator activity", "id": "GO:0030695", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030695", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZRJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZRJ5" } ], "pmid": "" }, { "name": "GDP-dissociation inhibitor activity", "id": "GO:0005092", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005092", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZRJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZRJ5" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZRJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZRJ5" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZRJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZRJ5" } ], "pmid": "" } ], "biological_process": [ { "name": "Rho protein signal transduction", "id": "GO:0007266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007266", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZRJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZRJ5" } ], "pmid": "" }, { "name": "regulation of protein localization", "id": "GO:0032880", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032880", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZRJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZRJ5" } ], "pmid": "" }, { "name": "blastocyst hatching", "id": "GO:0001835", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001835", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZRJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZRJ5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I5ZRJ5-1", "start_pos": "35", "end_pos": "35", "site_lbl": "Thr35", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 35, "start_aa": "Thr", "end_pos": 35, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr35", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I5ZRJ5-1" }, { "uniprot_canonical_ac": "A0A8I5ZRU6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZRU6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZRU6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 421, "chemical_mass": 48263.0, "gene_names": "ENSRNOG00000064752;Serpina1fl2", "protein_name": "", "disease": [], "molecular_function": [ { "name": "serine-type endopeptidase inhibitor activity", "id": "GO:0004867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004867", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZRU6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZRU6" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZRU6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZRU6" } ], "pmid": "" } ], "biological_process": [ { "name": "response to cytokine", "id": "GO:0034097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034097", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZRU6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZRU6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZRU6-1" }, { "uniprot_canonical_ac": "A0A8I5ZUT2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUT2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUT2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 583, "chemical_mass": 59260.0, "gene_names": "Irgq;Irgq;RGD1309409", "protein_name": "", "disease": [], "molecular_function": [ { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUT2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUT2" } ], "pmid": "" }, { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUT2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUT2" } ], "pmid": "" } ], "cellular_component": [ { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUT2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUT2" } ], "pmid": "" }, { "name": "autophagosome", "id": "GO:0005776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005776", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUT2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUT2" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of autophagy", "id": "GO:0010508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010508", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUT2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUT2" } ], "pmid": "" }, { "name": "substrate localization to autophagosome", "id": "GO:0061753", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061753", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUT2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUT2" } ], "pmid": "" }, { "name": "protein quality control for misfolded or incompletely synthesized proteins", "id": "GO:0006515", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006515", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUT2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUT2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I5ZUT2-1", "start_pos": "282", "end_pos": "282", "site_lbl": "Thr282", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 282, "start_aa": "Thr", "end_pos": 282, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr282", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I5ZUT2-1" }, { "uniprot_canonical_ac": "A0A8I5ZZ08-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZZ08", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZZ08" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 493, "chemical_mass": 56389.0, "gene_names": "LOC103691092", "protein_name": "Cytochrome P450", "disease": [ { "disease_id": "DOID:0050742", "name": "nicotine dependence", "description": "A substance dependence that is characterized by a physical dependence on nicotine.", "url": "https://disease-ontology.org/term/DOID:0050742", "evidence": [ { "id": "0050742", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050742" } ], "weight": 0.0 }, { "disease_id": "DOID:399", "name": "tuberculosis", "description": "A primary bacterial infectious disease that is located_in lungs, located_in lymph nodes, located_in pericardium, located_in brain, located_in pleura or located_in gastrointestinal tract, has_material_basis_in Mycobacterium tuberculosis, which is transmitted_by droplets released into the air when an infected person coughs or sneezes.", "url": "https://disease-ontology.org/term/DOID:399", "evidence": [ { "id": "399", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:399" } ], "weight": 0.0 }, { "disease_id": "DOID:526", "name": "human immunodeficiency virus infectious disease", "description": "A viral infectious disease that results in destruction of immune system, leading to life-threatening opportunistic infections and cancers, has_material_basis_in Human immunodeficiency virus 1 (Lentivirus humimdef1) or Human immunodeficiency virus 2 (Lentivirus humimdef2), which are transmitted by sexual contact, transmitted by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted by congenital method, and transmitted by contaminated needles. The virus infects helper T cells (CD4+ T cells) which are directly or indirectly destroyed, macrophages, and dendritic cells. The infection has symptom diarrhea, has symptom fatigue, has symptom fever, has symptom vaginal yeast infection, has symptom headache, has symptom mouth sores, has symptom muscle aches, has symptom sore throat, and has symptom swollen lymph glands.", "url": "https://disease-ontology.org/term/DOID:526", "evidence": [ { "id": "526", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:526" } ], "weight": 0.0 }, { "disease_id": "DOID:9119", "name": "acute myeloid leukemia", "description": "A myeloid leukemia that is characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal blood cells.", "url": "https://disease-ontology.org/term/DOID:9119", "evidence": [ { "id": "9119", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9119" } ], "weight": 0.0 }, { "disease_id": "DOID:9828", "name": "neonatal abstinence syndrome", "description": "A withdrawal disorder that is characterized by a group of problems that occur in a newborn who was exposed to addictive illegal or prescription drugs while in the mother's womb or postnatally following the discontinuance of drug treatment.", "url": "https://disease-ontology.org/term/DOID:9828", "evidence": [ { "id": "9828", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9828" } ], "weight": 0.0 }, { "disease_id": "DOID:9974", "name": "drug dependence", "description": "A substance dependence that involves the continued use of drugs despite problems related to use of the substance.", "url": "https://disease-ontology.org/term/DOID:9974", "evidence": [ { "id": "9974", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9974" } ], "weight": 0.0 }, { "disease_id": "DOID:9976", "name": "heroin dependence", "description": "An opiate dependence that involves the continued use of heroin despite problems related to use of the substance.", "url": "https://disease-ontology.org/term/DOID:9976", "evidence": [ { "id": "9976", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9976" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZZ08", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZZ08" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZZ08", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZZ08" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen", "id": "GO:0016712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016712", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZZ08", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZZ08" } ], "pmid": "" }, { "name": "arachidonate epoxygenase activity", "id": "GO:0008392", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008392", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZZ08", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZZ08" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZZ08", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZZ08" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZZ08", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZZ08" } ], "pmid": "" } ], "biological_process": [ { "name": "xenobiotic metabolic process", "id": "GO:0006805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006805", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZZ08", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZZ08" } ], "pmid": "" }, { "name": "epoxygenase P450 pathway", "id": "GO:0019373", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019373", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZZ08", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZZ08" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZZ08-1" }, { "uniprot_canonical_ac": "A0A8I6A253-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A253", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A253" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 94, "chemical_mass": 11060.0, "gene_names": "ENSRNOG00000064868", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6A253-1" }, { "uniprot_canonical_ac": "A0A8I6AAE1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AAE1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AAE1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 7434, "chemical_mass": 778537.0, "gene_names": "Ahnak2", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AAE1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AAE1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AAE1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AAE1" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AAE1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AAE1" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AAE1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AAE1" } ], "pmid": "" }, { "name": "cytoplasmic vesicle membrane", "id": "GO:0030659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030659", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AAE1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AAE1" } ], "pmid": "" }, { "name": "Z disc", "id": "GO:0030018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030018", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AAE1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AAE1" } ], "pmid": "" }, { "name": "costamere", "id": "GO:0043034", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043034", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AAE1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AAE1" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of RNA splicing", "id": "GO:0043484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043484", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AAE1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AAE1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AAE1-1" }, { "uniprot_canonical_ac": "A0A8I6ABB1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABB1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABB1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 510, "chemical_mass": 60159.0, "gene_names": "Zfp955b;LOC120093538;Zfp955b", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABB1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABB1" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABB1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABB1" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABB1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABB1" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABB1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABB1" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABB1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABB1" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABB1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABB1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6ABB1-1" }, { "uniprot_canonical_ac": "A0A8I6ABM0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABM0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABM0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 219, "chemical_mass": 25155.0, "gene_names": "Rit1;RGD1559874;Rit1", "protein_name": "small monomeric GTPase", "disease": [ { "disease_id": "DOID:0060586", "name": "Noonan syndrome 8", "description": "A Noonan syndrome that has_material_basis_in caused by heterozygous mutation in the RIT1 gene on chromosome 1q22.", "url": "https://disease-ontology.org/term/DOID:0060586", "evidence": [ { "id": "0060586", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060586" } ], "weight": 0.0 }, { "disease_id": "DOID:0080690", "name": "RASopathy", "description": "A syndrome that has_material_basis_in mutations in genes that alter the Ras subfamily and mitogen-activated protein kinases that control signal transduction.", "url": "https://disease-ontology.org/term/DOID:0080690", "evidence": [ { "id": "0080690", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080690" } ], "weight": 0.0 }, { "disease_id": "DOID:3490", "name": "Noonan syndrome", "description": "A RASopathy that is characterized by mildly unusual facial features, short stature, heart defects, bleeding problems, skeletal malformations, and many other signs and symptoms.", "url": "https://disease-ontology.org/term/DOID:3490", "evidence": [ { "id": "3490", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3490" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABM0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABM0" } ], "pmid": "" }, { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABM0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABM0" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABM0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABM0" } ], "pmid": "" }, { "name": "G protein activity", "id": "GO:0003925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003925", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABM0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABM0" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABM0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABM0" } ], "pmid": "" } ], "biological_process": [ { "name": "Ras protein signal transduction", "id": "GO:0007265", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007265", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABM0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABM0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6ABM0-1" }, { "uniprot_canonical_ac": "A0A8I6ACT0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACT0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACT0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 573, "chemical_mass": 60853.0, "gene_names": "Hspd1l1;Hspd1l1;LOC103694176", "protein_name": "60 kDa heat shock protein, mitochondrial", "disease": [ { "disease_id": "DOID:0060789", "name": "hypomyelinating leukodystrophy 4", "description": "A hypomyelinating leukodystrophy characterized by autosomal recessive inheritance of hypotonia, nystagmus, psychomotor developmental delay, and severe hypomyelinating leukoencephalopathy that has_material_basis_in homozygous mutation in the HSPD1 gene on chromosome 2q33.", "url": "https://disease-ontology.org/term/DOID:0060789", "evidence": [ { "id": "0060789", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060789" } ], "weight": 0.0 }, { "disease_id": "DOID:0110766", "name": "hereditary spastic paraplegia 13", "description": "A hereditary spastic paraplegia that is characterized by a pure form of the disease with late onset and has_material_basis_in mutation in the HSPD1 gene on chromosome 2q33.", "url": "https://disease-ontology.org/term/DOID:0110766", "evidence": [ { "id": "0110766", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110766" } ], "weight": 0.0 }, { "disease_id": "DOID:10603", "name": "glucose intolerance", "description": "", "url": "https://disease-ontology.org/term/DOID:10603", "evidence": [ { "id": "10603", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10603" } ], "weight": 0.0 }, { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:12849", "name": "autistic disorder", "description": "An autism spectrum disorder that is characterized by symptoms across all three symptom domains (communication, social, restricted repetitive interests and behaviors), delayed language development, and symptom onset prior to age 3 years.", "url": "https://disease-ontology.org/term/DOID:12849", "evidence": [ { "id": "12849", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12849" } ], "weight": 0.0 }, { "disease_id": "DOID:14250", "name": "Down syndrome", "description": "A chromosomal duplication syndrome that is characterized by flat-looking facial features and weak muscle tone (hypotonia) in infancy and is caused by trisomy of all or a critical portion of chromosome 21 and is associated with intellectual disability.", "url": "https://disease-ontology.org/term/DOID:14250", "evidence": [ { "id": "14250", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14250" } ], "weight": 0.0 }, { "disease_id": "DOID:1485", "name": "cystic fibrosis", "description": "A syndrome that is characterized by the buildup of thick, sticky mucus that can damage many organs.", "url": "https://disease-ontology.org/term/DOID:1485", "evidence": [ { "id": "1485", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1485" } ], "weight": 0.0 }, { "disease_id": "DOID:2349", "name": "arteriosclerosis", "description": "An artery disease that is characterized by a thickening and hardening of arterial walls in the arteries.", "url": "https://disease-ontology.org/term/DOID:2349", "evidence": [ { "id": "2349", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2349" } ], "weight": 0.0 }, { "disease_id": "DOID:2476", "name": "hereditary spastic paraplegia", "description": "A paraplegia that is characterized by progressive stiffness and contraction (spasticity) in the lower limbs.", "url": "https://disease-ontology.org/term/DOID:2476", "evidence": [ { "id": "2476", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2476" } ], "weight": 0.0 }, { "disease_id": "DOID:3393", "name": "coronary artery disease", "description": "An artery disease that is characterized by plaque building up along the inner walls of the arteries of the heart resulting in a narrowing of the arteries and a reduced blood supply to the cardiac muscles.", "url": "https://disease-ontology.org/term/DOID:3393", "evidence": [ { "id": "3393", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3393" } ], "weight": 0.0 }, { "disease_id": "DOID:3407", "name": "carotid artery disease", "description": "", "url": "https://disease-ontology.org/term/DOID:3407", "evidence": [ { "id": "3407", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3407" } ], "weight": 0.0 }, { "disease_id": "DOID:676", "name": "systemic juvenile rheumatoid arthritis", "description": "A rheumatoid arthritis that involves an autoimmune disease onset in children under 16 which attacks the healthy cells and tissue of located_in joint.", "url": "https://disease-ontology.org/term/DOID:676", "evidence": [ { "id": "676", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:676" } ], "weight": 0.0 }, { "disease_id": "DOID:7148", "name": "rheumatoid arthritis", "description": "An arthritis that is an autoimmune disease which attacks healthy cells and tissue located_in joint.", "url": "https://disease-ontology.org/term/DOID:7148", "evidence": [ { "id": "7148", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7148" } ], "weight": 0.0 }, { "disease_id": "DOID:9074", "name": "systemic lupus erythematosus", "description": "A lupus erythematosus that is an inflammation of connective tissue marked by skin rashes, joint pain and swelling, inflammation of the kidneys and inflammation of the tissue surrounding the heart.", "url": "https://disease-ontology.org/term/DOID:9074", "evidence": [ { "id": "9074", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9074" } ], "weight": 0.0 }, { "disease_id": "DOID:9663", "name": "aphthous stomatitis", "description": "A stomatitis characterized by the repeated formation of benign and non-contagious mouth ulcers.", "url": "https://disease-ontology.org/term/DOID:9663", "evidence": [ { "id": "9663", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9663" } ], "weight": 0.0 } ], "biological_process": [ { "name": "positive regulation of interferon-alpha production", "id": "GO:0032727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032727", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACT0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACT0" } ], "pmid": "" }, { "name": "protein import into mitochondrial intermembrane space", "id": "GO:0045041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045041", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACT0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACT0" } ], "pmid": "" }, { "name": "positive regulation of interleukin-6 production", "id": "GO:0032755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032755", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACT0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACT0" } ], "pmid": "" }, { "name": "T cell activation", "id": "GO:0042110", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042110", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACT0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACT0" } ], "pmid": "" }, { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACT0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACT0" } ], "pmid": "" }, { "name": "positive regulation of type II interferon production", "id": "GO:0032729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032729", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACT0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACT0" } ], "pmid": "" }, { "name": "apoptotic mitochondrial changes", "id": "GO:0008637", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008637", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACT0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACT0" } ], "pmid": "" }, { "name": "positive regulation of T cell activation", "id": "GO:0050870", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050870", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACT0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACT0" } ], "pmid": "" }, { "name": "protein refolding", "id": "GO:0042026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042026", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACT0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACT0" } ], "pmid": "" }, { "name": "mitochondrial unfolded protein response", "id": "GO:0034514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034514", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACT0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACT0" } ], "pmid": "" } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACT0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACT0" } ], "pmid": "" }, { "name": "protein-folding chaperone binding", "id": "GO:0051087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051087", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACT0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACT0" } ], "pmid": "" }, { "name": "ATP-dependent protein folding chaperone", "id": "GO:0140662", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140662", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACT0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACT0" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACT0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACT0" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ACT0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ACT0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6ACT0-1", "start_pos": "54", "end_pos": "54", "site_lbl": "Thr54", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 54, "start_aa": "Thr", "end_pos": 54, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr54", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6ACT0-1" }, { "uniprot_canonical_ac": "A0A8I6AFA7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AFA7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AFA7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 309, "chemical_mass": 34592.0, "gene_names": "Or2y1c;Olr1394;Or2y1c;Or2y1", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AFA7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AFA7" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AFA7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AFA7" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AFA7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AFA7" } ], "pmid": "" } ], "biological_process": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AFA7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AFA7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AFA7-1" }, { "uniprot_canonical_ac": "A0A8I6AEP5-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEP5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEP5" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 564, "chemical_mass": 61734.0, "gene_names": "Paox", "protein_name": "", "disease": [ { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEP5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEP5" } ], "pmid": "" }, { "name": "peroxisomal matrix", "id": "GO:0005782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005782", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEP5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEP5" } ], "pmid": "" } ], "molecular_function": [ { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEP5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEP5" } ], "pmid": "" }, { "name": "polyamine oxidase activity", "id": "GO:0046592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046592", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEP5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEP5" } ], "pmid": "" } ], "biological_process": [ { "name": "spermidine catabolic process", "id": "GO:0046203", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046203", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEP5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEP5" } ], "pmid": "" }, { "name": "polyamine catabolic process", "id": "GO:0006598", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006598", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEP5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEP5" } ], "pmid": "" }, { "name": "putrescine biosynthetic process", "id": "GO:0009446", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009446", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEP5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEP5" } ], "pmid": "" }, { "name": "putrescine catabolic process", "id": "GO:0009447", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009447", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEP5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEP5" } ], "pmid": "" }, { "name": "spermine catabolic process", "id": "GO:0046208", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046208", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEP5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEP5" } ], "pmid": "" }, { "name": "positive regulation of spermidine biosynthetic process", "id": "GO:1901307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901307", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEP5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEP5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AEP5-1" }, { "uniprot_canonical_ac": "F7F4X8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F7F4X8", "url": "https://www.uniprot.org/uniprotkb/F7F4X8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 290, "chemical_mass": 31634.0, "gene_names": "Tnfrsf14;Tnfrsf14", "protein_name": "", "disease": [ { "disease_id": "DOID:2349", "name": "arteriosclerosis", "description": "An artery disease that is characterized by a thickening and hardening of arterial walls in the arteries.", "url": "https://disease-ontology.org/term/DOID:2349", "evidence": [ { "id": "2349", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2349" } ], "weight": 0.0 }, { "disease_id": "DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia.", "url": "https://disease-ontology.org/term/DOID:5844", "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F7F4X8", "url": "https://www.uniprot.org/uniprotkb/F7F4X8" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "F7F4X8", "url": "https://www.uniprot.org/uniprotkb/F7F4X8" } ], "pmid": "" }, { "name": "plasma membrane protein complex", "id": "GO:0098797", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098797", "evidence": [ { "database": "UniProtKB", "id": "F7F4X8", "url": "https://www.uniprot.org/uniprotkb/F7F4X8" } ], "pmid": "" }, { "name": "tumor necrosis factor receptor superfamily complex", "id": "GO:0002947", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002947", "evidence": [ { "database": "UniProtKB", "id": "F7F4X8", "url": "https://www.uniprot.org/uniprotkb/F7F4X8" } ], "pmid": "" } ], "biological_process": [ { "name": "defense response to Gram-negative bacterium", "id": "GO:0050829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050829", "evidence": [ { "database": "UniProtKB", "id": "F7F4X8", "url": "https://www.uniprot.org/uniprotkb/F7F4X8" } ], "pmid": "" }, { "name": "defense response to Gram-positive bacterium", "id": "GO:0050830", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050830", "evidence": [ { "database": "UniProtKB", "id": "F7F4X8", "url": "https://www.uniprot.org/uniprotkb/F7F4X8" } ], "pmid": "" }, { "name": "positive regulation of T cell migration", "id": "GO:2000406", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000406", "evidence": [ { "database": "UniProtKB", "id": "F7F4X8", "url": "https://www.uniprot.org/uniprotkb/F7F4X8" } ], "pmid": "" }, { "name": "T cell costimulation", "id": "GO:0031295", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031295", "evidence": [ { "database": "UniProtKB", "id": "F7F4X8", "url": "https://www.uniprot.org/uniprotkb/F7F4X8" } ], "pmid": "" }, { "name": "negative regulation of T cell proliferation", "id": "GO:0042130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042130", "evidence": [ { "database": "UniProtKB", "id": "F7F4X8", "url": "https://www.uniprot.org/uniprotkb/F7F4X8" } ], "pmid": "" }, { "name": "positive regulation of peptidyl-tyrosine phosphorylation", "id": "GO:0050731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050731", "evidence": [ { "database": "UniProtKB", "id": "F7F4X8", "url": "https://www.uniprot.org/uniprotkb/F7F4X8" } ], "pmid": "" }, { "name": "regulation of ERK1 and ERK2 cascade", "id": "GO:0070372", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070372", "evidence": [ { "database": "UniProtKB", "id": "F7F4X8", "url": "https://www.uniprot.org/uniprotkb/F7F4X8" } ], "pmid": "" }, { "name": "positive regulation of cytokine production involved in immune response", "id": "GO:0002720", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002720", "evidence": [ { "database": "UniProtKB", "id": "F7F4X8", "url": "https://www.uniprot.org/uniprotkb/F7F4X8" } ], "pmid": "" }, { "name": "negative regulation of alpha-beta T cell proliferation", "id": "GO:0046642", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046642", "evidence": [ { "database": "UniProtKB", "id": "F7F4X8", "url": "https://www.uniprot.org/uniprotkb/F7F4X8" } ], "pmid": "" }, { "name": "negative regulation of adaptive immune memory response", "id": "GO:1905675", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905675", "evidence": [ { "database": "UniProtKB", "id": "F7F4X8", "url": "https://www.uniprot.org/uniprotkb/F7F4X8" } ], "pmid": "" }, { "name": "regulation of T cell tolerance induction to tumor cell", "id": "GO:0002846", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002846", "evidence": [ { "database": "UniProtKB", "id": "F7F4X8", "url": "https://www.uniprot.org/uniprotkb/F7F4X8" } ], "pmid": "" } ], "molecular_function": [ { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "F7F4X8", "url": "https://www.uniprot.org/uniprotkb/F7F4X8" } ], "pmid": "" }, { "name": "receptor ligand activity", "id": "GO:0048018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048018", "evidence": [ { "database": "UniProtKB", "id": "F7F4X8", "url": "https://www.uniprot.org/uniprotkb/F7F4X8" } ], "pmid": "" }, { "name": "cytokine binding", "id": "GO:0019955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019955", "evidence": [ { "database": "UniProtKB", "id": "F7F4X8", "url": "https://www.uniprot.org/uniprotkb/F7F4X8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F7F4X8-1" }, { "uniprot_canonical_ac": "A0A8I5ZKS5-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZKS5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZKS5" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 767, "chemical_mass": 86355.0, "gene_names": "Sec23b;Sec23b", "protein_name": "Protein transport protein SEC23", "disease": [ { "disease_id": "DOID:0070307", "name": "craniolenticulosutural dysplasia", "description": "A syndrome in neonates that is characterized by facial dysmorphism, late-closing fontanels, cataract, and skeletal defects. It has_material_basis_in the mutation of the SEC23A gene on the 14th chromosome, with the underproduction in the collagen secreting pathway and distension of endoplasmic reticulum leading to bone defects.", "url": "https://disease-ontology.org/term/DOID:0070307", "evidence": [ { "id": "0070307", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070307" } ], "weight": 0.0 }, { "disease_id": "DOID:0081003", "name": "Cowden syndrome 7", "description": "A Cowden syndrome that has_material_basis_in heterozygous mutation in the SEC23B gene on chromosome 20p11.", "url": "https://disease-ontology.org/term/DOID:0081003", "evidence": [ { "id": "0081003", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081003" } ], "weight": 0.0 }, { "disease_id": "DOID:0111401", "name": "congenital dyserythropoietic anemia type II", "description": "A congenital dyserythropoietic anemia characterized by mild to severe anemia, bi- and multinucleated erythroblasts in bone marrow, jaundice and splenomegaly and may lead to liver iron overload and gallstones that has_material_basis_in homozygous or compound heterozygous mutation in the SEC23B gene on chromosome 20p11.23.", "url": "https://disease-ontology.org/term/DOID:0111401", "evidence": [ { "id": "0111401", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111401" } ], "weight": 0.0 }, { "disease_id": "DOID:5325", "name": "Roberts syndrome", "description": "A syndrome characterized by tetraphocomelia, craniofacial anomalies, growth retardation, intellectual disability, and cardiac and renal abnormalities that has_material_basis_in homozygous or compound heterozygous mutation in the ESCO2 gene on chromosome 8p21.1.", "url": "https://disease-ontology.org/term/DOID:5325", "evidence": [ { "id": "5325", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5325" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZKS5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZKS5" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZKS5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZKS5" } ], "pmid": "" }, { "name": "COPII vesicle coat", "id": "GO:0030127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030127", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZKS5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZKS5" } ], "pmid": "" }, { "name": "endoplasmic reticulum exit site", "id": "GO:0070971", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070971", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZKS5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZKS5" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZKS5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZKS5" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZKS5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZKS5" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZKS5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZKS5" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZKS5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZKS5" } ], "pmid": "" }, { "name": "COPII-coated vesicle budding", "id": "GO:0090114", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090114", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZKS5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZKS5" } ], "pmid": "" }, { "name": "COPII-coated vesicle cargo loading", "id": "GO:0090110", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090110", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZKS5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZKS5" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZKS5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZKS5" } ], "pmid": "" }, { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZKS5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZKS5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZKS5-1" }, { "uniprot_canonical_ac": "A0A8I6A1R7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1R7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1R7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1084, "chemical_mass": 124204.0, "gene_names": "Zfp729b;Zfp729b;Zfp748l1", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1R7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1R7" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1R7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1R7" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1R7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1R7" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1R7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1R7" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1R7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1R7" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1R7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1R7" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1R7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1R7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6A1R7-1" }, { "uniprot_canonical_ac": "A0A8I6A3C7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A3C7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A3C7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 659, "chemical_mass": 73022.0, "gene_names": "Snx9;Snx9", "protein_name": "", "disease": [ { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A3C7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A3C7" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A3C7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A3C7" } ], "pmid": "" }, { "name": "clathrin-coated pit", "id": "GO:0005905", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005905", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A3C7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A3C7" } ], "pmid": "" }, { "name": "cytoplasmic vesicle membrane", "id": "GO:0030659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030659", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A3C7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A3C7" } ], "pmid": "" }, { "name": "clathrin-coated vesicle", "id": "GO:0030136", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030136", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A3C7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A3C7" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A3C7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A3C7" } ], "pmid": "" }, { "name": "cuticular plate", "id": "GO:0032437", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032437", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A3C7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A3C7" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A3C7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A3C7" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A3C7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A3C7" } ], "pmid": "" }, { "name": "positive regulation of membrane protein ectodomain proteolysis", "id": "GO:0051044", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051044", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A3C7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A3C7" } ], "pmid": "" }, { "name": "receptor-mediated endocytosis", "id": "GO:0006898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006898", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A3C7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A3C7" } ], "pmid": "" }, { "name": "endosomal transport", "id": "GO:0016197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016197", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A3C7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A3C7" } ], "pmid": "" }, { "name": "mitotic cytokinesis", "id": "GO:0000281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000281", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A3C7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A3C7" } ], "pmid": "" }, { "name": "positive regulation of actin filament polymerization", "id": "GO:0030838", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030838", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A3C7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A3C7" } ], "pmid": "" }, { "name": "cleavage furrow formation", "id": "GO:0036089", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036089", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A3C7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A3C7" } ], "pmid": "" }, { "name": "lipid tube assembly", "id": "GO:0060988", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060988", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A3C7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A3C7" } ], "pmid": "" }, { "name": "plasma membrane tubulation", "id": "GO:0097320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097320", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A3C7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A3C7" } ], "pmid": "" }, { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A3C7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A3C7" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A3C7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A3C7" } ], "pmid": "" }, { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A3C7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A3C7" } ], "pmid": "" }, { "name": "1-phosphatidylinositol binding", "id": "GO:0005545", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005545", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A3C7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A3C7" } ], "pmid": "" }, { "name": "Arp2/3 complex binding", "id": "GO:0071933", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071933", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A3C7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A3C7" } ], "pmid": "" }, { "name": "phosphatidylinositol binding", "id": "GO:0035091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035091", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A3C7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A3C7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6A3C7-1" }, { "uniprot_canonical_ac": "A0A8I6ALA8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ALA8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ALA8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 688, "chemical_mass": 76383.0, "gene_names": "Tbc1d25;Oatl1;RGD1559711;Tbc1d25", "protein_name": "TBC1 domain family member 25", "disease": [], "molecular_function": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ALA8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ALA8" } ], "pmid": "" } ], "cellular_component": [ { "name": "autophagosome", "id": "GO:0005776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005776", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ALA8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ALA8" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of autophagosome maturation", "id": "GO:1901096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901096", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ALA8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ALA8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6ALA8-1" }, { "uniprot_canonical_ac": "A0A8I5Y0H0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y0H0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y0H0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 777, "chemical_mass": 89589.0, "gene_names": "Cul1", "protein_name": "Cullin-1", "disease": [], "molecular_function": [ { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y0H0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y0H0" } ], "pmid": "" }, { "name": "ubiquitin ligase complex scaffold activity", "id": "GO:0160072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160072", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y0H0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y0H0" } ], "pmid": "" } ], "biological_process": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y0H0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y0H0" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y0H0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y0H0" } ], "pmid": "" }, { "name": "cell population proliferation", "id": "GO:0008283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008283", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y0H0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y0H0" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y0H0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y0H0" } ], "pmid": "" }, { "name": "positive regulation of canonical NF-kappaB signal transduction", "id": "GO:0043123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043123", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y0H0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y0H0" } ], "pmid": "" }, { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y0H0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y0H0" } ], "pmid": "" }, { "name": "animal organ morphogenesis", "id": "GO:0009887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009887", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y0H0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y0H0" } ], "pmid": "" }, { "name": "cellular response to oxidative stress", "id": "GO:0034599", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034599", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y0H0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y0H0" } ], "pmid": "" }, { "name": "protein K48-linked ubiquitination", "id": "GO:0070936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070936", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y0H0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y0H0" } ], "pmid": "" }, { "name": "protein monoubiquitination", "id": "GO:0006513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006513", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y0H0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y0H0" } ], "pmid": "" }, { "name": "SCF-dependent proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0031146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031146", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y0H0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y0H0" } ], "pmid": "" } ], "cellular_component": [ { "name": "cullin-RING ubiquitin ligase complex", "id": "GO:0031461", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031461", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y0H0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y0H0" } ], "pmid": "" }, { "name": "Parkin-FBXW7-Cul1 ubiquitin ligase complex", "id": "GO:1990452", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990452", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y0H0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y0H0" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y0H0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y0H0" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y0H0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y0H0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y0H0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y0H0" } ], "pmid": "" }, { "name": "SCF ubiquitin ligase complex", "id": "GO:0019005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019005", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y0H0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y0H0" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y0H0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y0H0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5Y0H0-1" }, { "uniprot_canonical_ac": "A0A8I6AJN5-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJN5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJN5" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 215, "chemical_mass": 24253.0, "gene_names": "Cidea;Cidea", "protein_name": "Lipid transferase CIDEA", "disease": [ { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "lipid droplet", "id": "GO:0005811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005811", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJN5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJN5" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJN5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJN5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJN5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJN5" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJN5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJN5" } ], "pmid": "" }, { "name": "mitochondrial envelope", "id": "GO:0005740", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005740", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJN5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJN5" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJN5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJN5" } ], "pmid": "" } ], "biological_process": [ { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJN5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJN5" } ], "pmid": "" }, { "name": "lipid storage", "id": "GO:0019915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019915", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJN5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJN5" } ], "pmid": "" }, { "name": "cellular response to cold", "id": "GO:0070417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070417", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJN5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJN5" } ], "pmid": "" }, { "name": "temperature homeostasis", "id": "GO:0001659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001659", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJN5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJN5" } ], "pmid": "" }, { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJN5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJN5" } ], "pmid": "" }, { "name": "negative regulation of tumor necrosis factor production", "id": "GO:0032720", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032720", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJN5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJN5" } ], "pmid": "" }, { "name": "negative regulation of lipid catabolic process", "id": "GO:0050995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050995", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJN5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJN5" } ], "pmid": "" }, { "name": "fat cell differentiation", "id": "GO:0045444", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045444", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJN5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJN5" } ], "pmid": "" }, { "name": "response to stilbenoid", "id": "GO:0035634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJN5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJN5" } ], "pmid": "" }, { "name": "negative regulation of transforming growth factor beta receptor signaling pathway", "id": "GO:0030512", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030512", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJN5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJN5" } ], "pmid": "" }, { "name": "regulation of apoptotic DNA fragmentation", "id": "GO:1902510", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902510", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJN5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJN5" } ], "pmid": "" }, { "name": "negative regulation of execution phase of apoptosis", "id": "GO:1900118", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900118", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJN5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJN5" } ], "pmid": "" }, { "name": "negative regulation of cytokine production", "id": "GO:0001818", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001818", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJN5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJN5" } ], "pmid": "" }, { "name": "negative regulation of cold-induced thermogenesis", "id": "GO:0120163", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120163", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJN5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJN5" } ], "pmid": "" }, { "name": "lipid droplet fusion", "id": "GO:0160077", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160077", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJN5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJN5" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJN5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJN5" } ], "pmid": "" }, { "name": "regulation of macromolecule metabolic process", "id": "GO:0060255", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060255", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJN5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJN5" } ], "pmid": "" }, { "name": "negative regulation of multicellular organismal process", "id": "GO:0051241", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051241", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJN5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJN5" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJN5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJN5" } ], "pmid": "" }, { "name": "phosphatidic acid binding", "id": "GO:0070300", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070300", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJN5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJN5" } ], "pmid": "" }, { "name": "lipid transfer activity", "id": "GO:0120013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120013", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJN5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJN5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AJN5-1" }, { "uniprot_canonical_ac": "A0A8I6AG34-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AG34", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AG34" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1223, "chemical_mass": 137226.0, "gene_names": "Gse1", "protein_name": "", "disease": [ { "disease_id": "DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ], "weight": 0.0 } ], "biological_process": [ { "name": "in utero embryonic development", "id": "GO:0001701", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001701", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AG34", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AG34" } ], "pmid": "" }, { "name": "placenta development", "id": "GO:0001890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001890", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AG34", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AG34" } ], "pmid": "" }, { "name": "gene expression", "id": "GO:0010467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010467", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AG34", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AG34" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6AG34-1", "start_pos": "295", "end_pos": "295", "site_lbl": "Thr295", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 295, "start_aa": "Thr", "end_pos": 295, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr295", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6AG34-1" }, { "uniprot_canonical_ac": "A0A8I6AJZ8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJZ8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 488, "chemical_mass": 54158.0, "gene_names": "Cbll1;Cbll1", "protein_name": "E3 ubiquitin-protein ligase Hakai", "disease": [], "cellular_component": [ { "name": "RNA N6-methyladenosine methyltransferase complex", "id": "GO:0036396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036396", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJZ8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJZ8" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJZ8" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJZ8" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJZ8" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJZ8" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJZ8" } ], "pmid": "" } ], "biological_process": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJZ8" } ], "pmid": "" }, { "name": "regulation of cell adhesion", "id": "GO:0030155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030155", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJZ8" } ], "pmid": "" }, { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJZ8" } ], "pmid": "" }, { "name": "negative regulation of cell adhesion", "id": "GO:0007162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007162", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJZ8" } ], "pmid": "" }, { "name": "positive regulation of cell migration", "id": "GO:0030335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030335", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJZ8" } ], "pmid": "" }, { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJZ8" } ], "pmid": "" }, { "name": "positive regulation of endocytosis", "id": "GO:0045807", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045807", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJZ8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6AJZ8-1", "start_pos": "382", "end_pos": "382", "site_lbl": "Thr382", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 382, "start_aa": "Thr", "end_pos": 382, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr382", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6AJZ8-1" }, { "uniprot_canonical_ac": "A0A8I6A3T5-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A3T5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A3T5" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 211, "chemical_mass": 23832.0, "gene_names": "Mrpl58", "protein_name": "Large ribosomal subunit protein mL62", "disease": [], "molecular_function": [ { "name": "peptidyl-tRNA hydrolase activity", "id": "GO:0004045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004045", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A3T5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A3T5" } ], "pmid": "" }, { "name": "translation release factor activity, codon nonspecific", "id": "GO:0016150", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016150", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A3T5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A3T5" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrial large ribosomal subunit", "id": "GO:0005762", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005762", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A3T5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A3T5" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A3T5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A3T5" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A3T5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A3T5" } ], "pmid": "" } ], "biological_process": [ { "name": "mitochondrial translational termination", "id": "GO:0070126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070126", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A3T5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A3T5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6A3T5-1" }, { "uniprot_canonical_ac": "A0A8I6A572-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A572", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A572" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 260, "chemical_mass": 27873.0, "gene_names": "Fam168a", "protein_name": "", "disease": [], "biological_process": [ { "name": "positive regulation of base-excision repair", "id": "GO:1905053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905053", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A572", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A572" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6A572-1" }, { "uniprot_canonical_ac": "A0A8I5ZYD1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYD1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYD1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 168, "chemical_mass": 19269.0, "gene_names": "Cetn4;Cetn4", "protein_name": "", "disease": [], "molecular_function": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYD1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYD1" } ], "pmid": "" }, { "name": "G-protein beta/gamma-subunit complex binding", "id": "GO:0031683", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031683", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYD1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYD1" } ], "pmid": "" }, { "name": "heterotrimeric G-protein binding", "id": "GO:0032795", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032795", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYD1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYD1" } ], "pmid": "" } ], "cellular_component": [ { "name": "microtubule organizing center", "id": "GO:0005815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005815", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYD1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYD1" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYD1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYD1" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYD1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYD1" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYD1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYD1" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYD1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYD1" } ], "pmid": "" } ], "biological_process": [ { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYD1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYD1" } ], "pmid": "" }, { "name": "centriole replication", "id": "GO:0007099", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007099", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYD1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYD1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZYD1-1" }, { "uniprot_canonical_ac": "A0A8I5ZRX8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZRX8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZRX8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 662, "chemical_mass": 73065.0, "gene_names": "Egfem1", "protein_name": "", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZRX8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZRX8" } ], "pmid": "" } ], "molecular_function": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZRX8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZRX8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZRX8-1" }, { "uniprot_canonical_ac": "A0A8I6AWP1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AWP1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AWP1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1248, "chemical_mass": 143001.0, "gene_names": "AABR07054096.1;Cfap61;AABR07054096.1;Cfap61", "protein_name": "", "disease": [ { "disease_id": "DOID:0070311", "name": "oligoasthenoteratozoospermia", "description": "A form of male infertility that is characterized by a combination of low number or oligozoospermia, poor motility or asthenozoospermia, and abnormal shape or teratozoospermia of sperms. OAT is the most common cause of male subfertility.", "url": "https://disease-ontology.org/term/DOID:0070311", "evidence": [ { "id": "0070311", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070311" } ], "weight": 0.0 }, { "disease_id": "DOID:0070583", "name": "spermatogenic failure 84", "description": "A spermatogenic failure characterized by multiple morphologic abnormalities of the sperm flagella, resulting in severely reduced motility, that has_material_basis_in homozygous or compound heterozygous mutation in the CFAP61 gene on chromosome 20p11.23.", "url": "https://disease-ontology.org/term/DOID:0070583", "evidence": [ { "id": "0070583", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070583" } ], "weight": 0.0 } ], "biological_process": [ { "name": "flagellated sperm motility", "id": "GO:0030317", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030317", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AWP1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AWP1" } ], "pmid": "" }, { "name": "spermatid nucleus elongation", "id": "GO:0007290", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007290", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AWP1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AWP1" } ], "pmid": "" }, { "name": "sperm flagellum assembly", "id": "GO:0120316", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120316", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AWP1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AWP1" } ], "pmid": "" }, { "name": "sperm mitochondrial sheath assembly", "id": "GO:0120317", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120317", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AWP1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AWP1" } ], "pmid": "" } ], "cellular_component": [ { "name": "sperm flagellum", "id": "GO:0036126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036126", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AWP1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AWP1" } ], "pmid": "" }, { "name": "manchette", "id": "GO:0002177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002177", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AWP1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AWP1" } ], "pmid": "" }, { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AWP1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AWP1" } ], "pmid": "" }, { "name": "radial spoke stalk", "id": "GO:0001536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001536", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AWP1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AWP1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AWP1-1" }, { "uniprot_canonical_ac": "A6IPG1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A6IPG1", "url": "https://www.uniprot.org/uniprotkb/A6IPG1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 225, "chemical_mass": 24676.0, "gene_names": "Eef1b2;Eef1b2", "protein_name": "Elongation factor 1-beta", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A6IPG1", "url": "https://www.uniprot.org/uniprotkb/A6IPG1" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A6IPG1", "url": "https://www.uniprot.org/uniprotkb/A6IPG1" } ], "pmid": "" }, { "name": "eukaryotic translation elongation factor 1 complex", "id": "GO:0005853", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005853", "evidence": [ { "database": "UniProtKB", "id": "A6IPG1", "url": "https://www.uniprot.org/uniprotkb/A6IPG1" } ], "pmid": "" } ], "biological_process": [ { "name": "response to ethanol", "id": "GO:0045471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045471", "evidence": [ { "database": "UniProtKB", "id": "A6IPG1", "url": "https://www.uniprot.org/uniprotkb/A6IPG1" } ], "pmid": "" } ], "molecular_function": [ { "name": "translation elongation factor activity", "id": "GO:0003746", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003746", "evidence": [ { "database": "UniProtKB", "id": "A6IPG1", "url": "https://www.uniprot.org/uniprotkb/A6IPG1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A6IPG1-1", "start_pos": "106", "end_pos": "106", "site_lbl": "Ser106", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A6IPG1", "url": "https://www.uniprot.org/uniprotkb/A6IPG1" } ] } ] }, { "uniprot_canonical_ac": "A6IPG1-1", "start_pos": "174", "end_pos": "174", "site_lbl": "Ser174", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A6IPG1", "url": "https://www.uniprot.org/uniprotkb/A6IPG1" } ] } ] }, { "uniprot_canonical_ac": "A6IPG1-1", "start_pos": "42", "end_pos": "42", "site_lbl": "Ser42", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A6IPG1", "url": "https://www.uniprot.org/uniprotkb/A6IPG1" } ] } ] }, { "uniprot_canonical_ac": "A6IPG1-1", "start_pos": "83", "end_pos": "83", "site_lbl": "Ser83", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A6IPG1", "url": "https://www.uniprot.org/uniprotkb/A6IPG1" } ] } ] }, { "uniprot_canonical_ac": "A6IPG1-1", "start_pos": "88", "end_pos": "88", "site_lbl": "Thr88", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A6IPG1", "url": "https://www.uniprot.org/uniprotkb/A6IPG1" } ] } ] } ], "record_id": "A6IPG1-1" }, { "uniprot_canonical_ac": "A0A8I6GKX2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GKX2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GKX2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1367, "chemical_mass": 155213.0, "gene_names": "Tgap1l11;Tgap1l3;Tgap1l8;LOC103691539;LOC678817;RGD1563562;Tgap1l3;Tgap1l8", "protein_name": "Rho-GAP domain-containing protein", "disease": [], "molecular_function": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GKX2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GKX2" } ], "pmid": "" } ], "biological_process": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GKX2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GKX2" } ], "pmid": "" }, { "name": "regulation of Rho protein signal transduction", "id": "GO:0035023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035023", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GKX2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GKX2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6GKX2-1", "start_pos": "1145", "end_pos": "1145", "site_lbl": "Thr1145", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1145, "start_aa": "Thr", "end_pos": 1145, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1145", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I6GKX2-1", "start_pos": "597", "end_pos": "597", "site_lbl": "Thr597", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 597, "start_aa": "Thr", "end_pos": 597, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr597", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6GKX2-1" }, { "uniprot_canonical_ac": "A0A0G2KAG4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KAG4", "url": "https://www.uniprot.org/uniprotkb/A0A0G2KAG4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 187, "chemical_mass": 21022.0, "gene_names": "Fam3b", "protein_name": "", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KAG4", "url": "https://www.uniprot.org/uniprotkb/A0A0G2KAG4" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KAG4", "url": "https://www.uniprot.org/uniprotkb/A0A0G2KAG4" } ], "pmid": "" } ], "molecular_function": [ { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KAG4", "url": "https://www.uniprot.org/uniprotkb/A0A0G2KAG4" } ], "pmid": "" }, { "name": "cytokine activity", "id": "GO:0005125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005125", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KAG4", "url": "https://www.uniprot.org/uniprotkb/A0A0G2KAG4" } ], "pmid": "" } ], "biological_process": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KAG4", "url": "https://www.uniprot.org/uniprotkb/A0A0G2KAG4" } ], "pmid": "" }, { "name": "insulin secretion", "id": "GO:0030073", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030073", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KAG4", "url": "https://www.uniprot.org/uniprotkb/A0A0G2KAG4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A0G2KAG4-1" }, { "uniprot_canonical_ac": "A0A8I5ZPC4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZPC4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZPC4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 355, "chemical_mass": 39256.0, "gene_names": "Slc35d1", "protein_name": "", "disease": [ { "disease_id": "DOID:0050775", "name": "schneckenbecken dysplasia", "description": "An osteochondrodysplasia that is characterized by hypoplastic iliac bones, hypoplastic vertebral bodies, short ribs and broad long bones, prenatally lethal, has_material_basis_in homozygous or compound heterozygous mutation in the SLC35D1 gene on chromosome 1p31.", "url": "https://disease-ontology.org/term/DOID:0050775", "evidence": [ { "id": "0050775", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050775" } ], "weight": 0.0 }, { "disease_id": "DOID:1596", "name": "depressive disorder", "description": "A mood disorder characterized by persistent sadness, emptiness, or irritability and decreased ability to function.", "url": "https://disease-ontology.org/term/DOID:1596", "evidence": [ { "id": "1596", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1596" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZPC4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZPC4" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZPC4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZPC4" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZPC4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZPC4" } ], "pmid": "" } ], "molecular_function": [ { "name": "antiporter activity", "id": "GO:0015297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015297", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZPC4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZPC4" } ], "pmid": "" }, { "name": "pyrimidine nucleotide-sugar transmembrane transporter activity", "id": "GO:0015165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015165", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZPC4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZPC4" } ], "pmid": "" }, { "name": "UDP-glucuronate transmembrane transporter activity", "id": "GO:0005461", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005461", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZPC4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZPC4" } ], "pmid": "" }, { "name": "UDP-N-acetylglucosamine transmembrane transporter activity", "id": "GO:0005462", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005462", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZPC4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZPC4" } ], "pmid": "" }, { "name": "UDP-N-acetylgalactosamine transmembrane transporter activity", "id": "GO:0005463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005463", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZPC4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZPC4" } ], "pmid": "" } ], "biological_process": [ { "name": "chondroitin sulfate proteoglycan biosynthetic process", "id": "GO:0050650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050650", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZPC4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZPC4" } ], "pmid": "" }, { "name": "pyrimidine nucleotide-sugar transmembrane transport", "id": "GO:0090481", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090481", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZPC4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZPC4" } ], "pmid": "" }, { "name": "embryonic skeletal system development", "id": "GO:0048706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048706", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZPC4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZPC4" } ], "pmid": "" }, { "name": "nucleotide-sugar transmembrane transport", "id": "GO:0015780", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015780", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZPC4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZPC4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZPC4-1" }, { "uniprot_canonical_ac": "A0A8I5ZVG2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZVG2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZVG2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 938, "chemical_mass": 104893.0, "gene_names": "Ctnnd1;Catns;Ctnnd1;P120", "protein_name": "", "disease": [ { "disease_id": "DOID:0050866", "name": "oral squamous cell carcinoma", "description": "An oral cavity cancer that has_material_basis_in squamous cells.", "url": "https://disease-ontology.org/term/DOID:0050866", "evidence": [ { "id": "0050866", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050866" } ], "weight": 0.0 }, { "disease_id": "DOID:0060041", "name": "autism spectrum disorder", "description": "A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior.", "url": "https://disease-ontology.org/term/DOID:0060041", "evidence": [ { "id": "0060041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060041" } ], "weight": 0.0 }, { "disease_id": "DOID:0080346", "name": "blepharocheilodontic syndrome 2", "description": "A blepharocheilodontic syndrome that has_material_basis_in heterozygous mutation in the CTNND1 gene on chromosome 11q12.", "url": "https://disease-ontology.org/term/DOID:0080346", "evidence": [ { "id": "0080346", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080346" } ], "weight": 0.0 }, { "disease_id": "DOID:6432", "name": "pulmonary hypertension", "description": "A hypertension characterized by an increase of blood pressure in the pulmonary artery, pulmonary vein or pulmonary capillaries.", "url": "https://disease-ontology.org/term/DOID:6432", "evidence": [ { "id": "6432", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6432" } ], "weight": 0.0 } ], "biological_process": [ { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZVG2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZVG2" } ], "pmid": "" }, { "name": "negative regulation of D-glucose transmembrane transport", "id": "GO:0010829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZVG2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZVG2" } ], "pmid": "" }, { "name": "negative regulation of intracellular signal transduction", "id": "GO:1902532", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902532", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZVG2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZVG2" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZVG2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZVG2" } ], "pmid": "" }, { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZVG2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZVG2" } ], "pmid": "" }, { "name": "kidney development", "id": "GO:0001822", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001822", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZVG2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZVG2" } ], "pmid": "" }, { "name": "positive regulation of peptidyl-tyrosine autophosphorylation", "id": "GO:1900086", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900086", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZVG2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZVG2" } ], "pmid": "" }, { "name": "positive regulation of protein processing", "id": "GO:0010954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010954", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZVG2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZVG2" } ], "pmid": "" }, { "name": "protein stabilization", "id": "GO:0050821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050821", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZVG2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZVG2" } ], "pmid": "" }, { "name": "morphogenesis of a polarized epithelium", "id": "GO:0001738", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001738", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZVG2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZVG2" } ], "pmid": "" }, { "name": "glomerulus morphogenesis", "id": "GO:0072102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072102", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZVG2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZVG2" } ], "pmid": "" }, { "name": "cell migration involved in sprouting angiogenesis", "id": "GO:0002042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002042", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZVG2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZVG2" } ], "pmid": "" }, { "name": "salivary gland morphogenesis", "id": "GO:0007435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007435", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZVG2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZVG2" } ], "pmid": "" }, { "name": "cell-cell adhesion mediated by cadherin", "id": "GO:0044331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044331", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZVG2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZVG2" } ], "pmid": "" }, { "name": "epithelial cell differentiation involved in salivary gland development", "id": "GO:0060690", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060690", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZVG2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZVG2" } ], "pmid": "" }, { "name": "regulation of postsynaptic membrane neurotransmitter receptor levels", "id": "GO:0099072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099072", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZVG2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZVG2" } ], "pmid": "" }, { "name": "positive regulation of protein localization to cell-cell junction", "id": "GO:0150107", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0150107", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZVG2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZVG2" } ], "pmid": "" }, { "name": "negative regulation of blood vessel branching", "id": "GO:1905554", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905554", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZVG2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZVG2" } ], "pmid": "" } ], "cellular_component": [ { "name": "anchoring junction", "id": "GO:0070161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070161", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZVG2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZVG2" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZVG2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZVG2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZVG2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZVG2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZVG2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZVG2" } ], "pmid": "" }, { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZVG2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZVG2" } ], "pmid": "" }, { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZVG2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZVG2" } ], "pmid": "" }, { "name": "presynaptic active zone cytoplasmic component", "id": "GO:0098831", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098831", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZVG2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZVG2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZVG2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZVG2" } ], "pmid": "" }, { "name": "cell-cell junction", "id": "GO:0005911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005911", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZVG2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZVG2" } ], "pmid": "" }, { "name": "bicellular tight junction", "id": "GO:0005923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005923", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZVG2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZVG2" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZVG2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZVG2" } ], "pmid": "" }, { "name": "lamellipodium", "id": "GO:0030027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030027", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZVG2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZVG2" } ], "pmid": "" }, { "name": "growth cone", "id": "GO:0030426", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030426", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZVG2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZVG2" } ], "pmid": "" }, { "name": "dendritic spine", "id": "GO:0043197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043197", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZVG2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZVG2" } ], "pmid": "" }, { "name": "catenin complex", "id": "GO:0016342", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016342", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZVG2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZVG2" } ], "pmid": "" }, { "name": "midbody", "id": "GO:0030496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030496", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZVG2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZVG2" } ], "pmid": "" }, { "name": "postsynaptic density, intracellular component", "id": "GO:0099092", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099092", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZVG2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZVG2" } ], "pmid": "" }, { "name": "flotillin complex", "id": "GO:0016600", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016600", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZVG2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZVG2" } ], "pmid": "" }, { "name": "zonula adherens", "id": "GO:0005915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005915", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZVG2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZVG2" } ], "pmid": "" }, { "name": "apicolateral plasma membrane", "id": "GO:0016327", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016327", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZVG2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZVG2" } ], "pmid": "" }, { "name": "hippocampal mossy fiber to CA3 synapse", "id": "GO:0098686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098686", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZVG2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZVG2" } ], "pmid": "" }, { "name": "Schaffer collateral - CA1 synapse", "id": "GO:0098685", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098685", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZVG2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZVG2" } ], "pmid": "" } ], "molecular_function": [ { "name": "cadherin binding", "id": "GO:0045296", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045296", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZVG2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZVG2" } ], "pmid": "" }, { "name": "signaling receptor binding", "id": "GO:0005102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005102", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZVG2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZVG2" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZVG2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZVG2" } ], "pmid": "" }, { "name": "protein domain specific binding", "id": "GO:0019904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019904", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZVG2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZVG2" } ], "pmid": "" }, { "name": "cell adhesion molecule binding", "id": "GO:0050839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050839", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZVG2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZVG2" } ], "pmid": "" }, { "name": "beta-catenin binding", "id": "GO:0008013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008013", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZVG2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZVG2" } ], "pmid": "" }, { "name": "phosphatase inhibitor activity", "id": "GO:0019212", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019212", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZVG2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZVG2" } ], "pmid": "" }, { "name": "protein phosphatase binding", "id": "GO:0019903", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019903", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZVG2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZVG2" } ], "pmid": "" }, { "name": "phosphatase binding", "id": "GO:0019902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019902", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZVG2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZVG2" } ], "pmid": "" }, { "name": "cell-cell adhesion mediator activity", "id": "GO:0098632", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098632", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZVG2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZVG2" } ], "pmid": "" }, { "name": "protein tyrosine kinase binding", "id": "GO:1990782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990782", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZVG2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZVG2" } ], "pmid": "" }, { "name": "protein sequestering activity", "id": "GO:0140311", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140311", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZVG2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZVG2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZVG2-1" }, { "uniprot_canonical_ac": "A0A8I6A1C4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1C4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1C4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1814, "chemical_mass": 207152.0, "gene_names": "Shprh", "protein_name": "E3 ubiquitin-protein ligase SHPRH", "disease": [], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1C4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1C4" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1C4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1C4" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1C4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1C4" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1C4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1C4" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1C4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1C4" } ], "pmid": "" }, { "name": "helicase activity", "id": "GO:0004386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004386", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1C4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1C4" } ], "pmid": "" }, { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1C4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1C4" } ], "pmid": "" }, { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1C4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1C4" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1C4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1C4" } ], "pmid": "" }, { "name": "nucleosome", "id": "GO:0000786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000786", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1C4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1C4" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1C4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1C4" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1C4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1C4" } ], "pmid": "" }, { "name": "nucleosome assembly", "id": "GO:0006334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006334", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1C4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1C4" } ], "pmid": "" }, { "name": "protein polyubiquitination", "id": "GO:0000209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000209", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1C4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1C4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6A1C4-1" }, { "uniprot_canonical_ac": "A0A8I6ABG6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABG6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABG6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 2558, "chemical_mass": 271338.0, "gene_names": "Tln1;Tln1;Tln", "protein_name": "", "disease": [], "biological_process": [ { "name": "cell-substrate junction assembly", "id": "GO:0007044", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007044", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABG6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABG6" } ], "pmid": "" }, { "name": "integrin-mediated signaling pathway", "id": "GO:0007229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007229", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABG6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABG6" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABG6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABG6" } ], "pmid": "" }, { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABG6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABG6" } ], "pmid": "" }, { "name": "cortical actin cytoskeleton organization", "id": "GO:0030866", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030866", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABG6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABG6" } ], "pmid": "" }, { "name": "integrin activation", "id": "GO:0033622", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033622", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABG6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABG6" } ], "pmid": "" }, { "name": "cortical microtubule organization", "id": "GO:0043622", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043622", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABG6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABG6" } ], "pmid": "" }, { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABG6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABG6" } ], "pmid": "" }, { "name": "cell junction assembly", "id": "GO:0034329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034329", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABG6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABG6" } ], "pmid": "" } ], "molecular_function": [ { "name": "integrin binding", "id": "GO:0005178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005178", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABG6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABG6" } ], "pmid": "" }, { "name": "structural constituent of cytoskeleton", "id": "GO:0005200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005200", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABG6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABG6" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABG6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABG6" } ], "pmid": "" }, { "name": "vinculin binding", "id": "GO:0017166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017166", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABG6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABG6" } ], "pmid": "" }, { "name": "LIM domain binding", "id": "GO:0030274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030274", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABG6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABG6" } ], "pmid": "" }, { "name": "phosphatidylserine binding", "id": "GO:0001786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001786", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABG6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABG6" } ], "pmid": "" }, { "name": "phosphatidylinositol binding", "id": "GO:0035091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035091", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABG6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABG6" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABG6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABG6" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABG6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABG6" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABG6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABG6" } ], "pmid": "" }, { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABG6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABG6" } ], "pmid": "" }, { "name": "focal adhesion", "id": "GO:0005925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005925", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABG6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABG6" } ], "pmid": "" }, { "name": "ruffle", "id": "GO:0001726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001726", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABG6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABG6" } ], "pmid": "" }, { "name": "centriolar satellite", "id": "GO:0034451", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034451", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABG6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABG6" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABG6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABG6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6ABG6-1" }, { "uniprot_canonical_ac": "O70631-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "O70631", "url": "https://www.uniprot.org/uniprotkb/O70631" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 561, "chemical_mass": 62170.0, "gene_names": "Ces2c;Ces2;ACH M1;CESRL4;Ces2c;Ces2l;Ces2;LOC100910040", "protein_name": "Acylcarnitine hydrolase", "disease": [], "molecular_function": [ { "name": "acylcarnitine hydrolase activity", "id": "GO:0047619", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047619", "evidence": [ { "database": "UniProtKB", "id": "O70631", "url": "https://www.uniprot.org/uniprotkb/O70631" } ], "pmid": "" }, { "name": "retinyl-palmitate esterase activity", "id": "GO:0050253", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050253", "evidence": [ { "database": "UniProtKB", "id": "O70631", "url": "https://www.uniprot.org/uniprotkb/O70631" } ], "pmid": "" }, { "name": "all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity", "id": "GO:0047376", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047376", "evidence": [ { "database": "UniProtKB", "id": "O70631", "url": "https://www.uniprot.org/uniprotkb/O70631" } ], "pmid": "" }, { "name": "carboxylesterase activity", "id": "GO:0106435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106435", "evidence": [ { "database": "UniProtKB", "id": "O70631", "url": "https://www.uniprot.org/uniprotkb/O70631" } ], "pmid": "" }, { "name": "carboxylic ester hydrolase activity", "id": "GO:0052689", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052689", "evidence": [ { "database": "UniProtKB", "id": "O70631", "url": "https://www.uniprot.org/uniprotkb/O70631" } ], "pmid": "" } ], "biological_process": [ { "name": "retinoid metabolic process", "id": "GO:0001523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001523", "evidence": [ { "database": "UniProtKB", "id": "O70631", "url": "https://www.uniprot.org/uniprotkb/O70631" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "O70631", "url": "https://www.uniprot.org/uniprotkb/O70631" } ], "pmid": "" }, { "name": "intracellular membrane-bounded organelle", "id": "GO:0043231", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043231", "evidence": [ { "database": "UniProtKB", "id": "O70631", "url": "https://www.uniprot.org/uniprotkb/O70631" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "O70631-1" }, { "uniprot_canonical_ac": "A0A8I5XWR9-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XWR9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XWR9" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 903, "chemical_mass": 101055.0, "gene_names": "Zc3h12c;RGD1565078;Zc3h12c", "protein_name": "", "disease": [], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XWR9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XWR9" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XWR9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XWR9" } ], "pmid": "" }, { "name": "endonuclease activity", "id": "GO:0004519", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004519", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XWR9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XWR9" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XWR9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XWR9" } ], "pmid": "" }, { "name": "RNA endonuclease activity", "id": "GO:0004521", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004521", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XWR9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XWR9" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XWR9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XWR9" } ], "pmid": "" }, { "name": "cytoplasmic ribonucleoprotein granule", "id": "GO:0036464", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036464", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XWR9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XWR9" } ], "pmid": "" } ], "biological_process": [ { "name": "3'-UTR-mediated mRNA destabilization", "id": "GO:0061158", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061158", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XWR9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XWR9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I5XWR9-1", "start_pos": "14", "end_pos": "14", "site_lbl": "Thr14", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 14, "start_aa": "Thr", "end_pos": 14, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr14", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I5XWR9-1" }, { "uniprot_canonical_ac": "Q4KLN3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "Q4KLN3", "url": "https://www.uniprot.org/uniprotkb/Q4KLN3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 655, "chemical_mass": 73856.0, "gene_names": "Srpk1;Srpk1", "protein_name": "SRSF protein kinase 1", "disease": [], "molecular_function": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "Q4KLN3", "url": "https://www.uniprot.org/uniprotkb/Q4KLN3" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q4KLN3", "url": "https://www.uniprot.org/uniprotkb/Q4KLN3" } ], "pmid": "" }, { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "Q4KLN3", "url": "https://www.uniprot.org/uniprotkb/Q4KLN3" } ], "pmid": "" }, { "name": "protein serine kinase activity", "id": "GO:0106310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106310", "evidence": [ { "database": "UniProtKB", "id": "Q4KLN3", "url": "https://www.uniprot.org/uniprotkb/Q4KLN3" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q4KLN3", "url": "https://www.uniprot.org/uniprotkb/Q4KLN3" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "Q4KLN3", "url": "https://www.uniprot.org/uniprotkb/Q4KLN3" } ], "pmid": "" }, { "name": "nuclear matrix", "id": "GO:0016363", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016363", "evidence": [ { "database": "UniProtKB", "id": "Q4KLN3", "url": "https://www.uniprot.org/uniprotkb/Q4KLN3" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "Q4KLN3", "url": "https://www.uniprot.org/uniprotkb/Q4KLN3" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q4KLN3", "url": "https://www.uniprot.org/uniprotkb/Q4KLN3" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "Q4KLN3", "url": "https://www.uniprot.org/uniprotkb/Q4KLN3" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q4KLN3", "url": "https://www.uniprot.org/uniprotkb/Q4KLN3" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "Q4KLN3", "url": "https://www.uniprot.org/uniprotkb/Q4KLN3" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "Q4KLN3", "url": "https://www.uniprot.org/uniprotkb/Q4KLN3" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "Q4KLN3", "url": "https://www.uniprot.org/uniprotkb/Q4KLN3" } ], "pmid": "" }, { "name": "chromosome segregation", "id": "GO:0007059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007059", "evidence": [ { "database": "UniProtKB", "id": "Q4KLN3", "url": "https://www.uniprot.org/uniprotkb/Q4KLN3" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "Q4KLN3", "url": "https://www.uniprot.org/uniprotkb/Q4KLN3" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "Q4KLN3", "url": "https://www.uniprot.org/uniprotkb/Q4KLN3" } ], "pmid": "" }, { "name": "protein phosphorylation", "id": "GO:0006468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006468", "evidence": [ { "database": "UniProtKB", "id": "Q4KLN3", "url": "https://www.uniprot.org/uniprotkb/Q4KLN3" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "Q4KLN3", "url": "https://www.uniprot.org/uniprotkb/Q4KLN3" } ], "pmid": "" }, { "name": "negative regulation of viral genome replication", "id": "GO:0045071", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045071", "evidence": [ { "database": "UniProtKB", "id": "Q4KLN3", "url": "https://www.uniprot.org/uniprotkb/Q4KLN3" } ], "pmid": "" }, { "name": "spliceosomal complex assembly", "id": "GO:0000245", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000245", "evidence": [ { "database": "UniProtKB", "id": "Q4KLN3", "url": "https://www.uniprot.org/uniprotkb/Q4KLN3" } ], "pmid": "" }, { "name": "positive regulation of viral genome replication", "id": "GO:0045070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045070", "evidence": [ { "database": "UniProtKB", "id": "Q4KLN3", "url": "https://www.uniprot.org/uniprotkb/Q4KLN3" } ], "pmid": "" }, { "name": "regulation of mRNA processing", "id": "GO:0050684", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050684", "evidence": [ { "database": "UniProtKB", "id": "Q4KLN3", "url": "https://www.uniprot.org/uniprotkb/Q4KLN3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q4KLN3-1" }, { "uniprot_canonical_ac": "A0A8I5ZK79-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZK79", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZK79" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 219, "chemical_mass": 24982.0, "gene_names": "Pigf;Pigf", "protein_name": "", "disease": [], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZK79", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZK79" } ], "pmid": "" } ], "biological_process": [ { "name": "GPI anchor biosynthetic process", "id": "GO:0006506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006506", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZK79", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZK79" } ], "pmid": "" } ], "molecular_function": [ { "name": "mannose-ethanolamine phosphotransferase activity", "id": "GO:0051377", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051377", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZK79", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZK79" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZK79-1" }, { "uniprot_canonical_ac": "A0A8I5ZNG4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNG4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNG4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1733, "chemical_mass": 194656.0, "gene_names": "Rictor;Rictor", "protein_name": "", "disease": [ { "disease_id": "DOID:0050861", "name": "colorectal adenocarcinoma", "description": "A colorectal carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:0050861", "evidence": [ { "id": "0050861", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050861" } ], "weight": 0.0 }, { "disease_id": "DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ], "weight": 0.0 }, { "disease_id": "DOID:1324", "name": "lung cancer", "description": "A respiratory system cancer that is located_in the lung.", "url": "https://disease-ontology.org/term/DOID:1324", "evidence": [ { "id": "1324", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1324" } ], "weight": 0.0 }, { "disease_id": "DOID:219", "name": "colon cancer", "description": "A colorectal cancer that is located_in the colon.", "url": "https://disease-ontology.org/term/DOID:219", "evidence": [ { "id": "219", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:219" } ], "weight": 0.0 }, { "disease_id": "DOID:3007", "name": "breast ductal carcinoma", "description": "A breast carcinoma that derives_from the lining of milk ducts.", "url": "https://disease-ontology.org/term/DOID:3007", "evidence": [ { "id": "3007", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3007" } ], "weight": 0.0 }, { "disease_id": "DOID:3121", "name": "gallbladder cancer", "description": "A biliary tract cancer that is located_in the gallbladder.", "url": "https://disease-ontology.org/term/DOID:3121", "evidence": [ { "id": "3121", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3121" } ], "weight": 0.0 }, { "disease_id": "DOID:3319", "name": "lymphangioleiomyomatosis", "description": "A lung disease that is characterized by progressive cystic destruction of the lung and lymphatic abnormalities, frequently associated with renal angiomyolipomas.", "url": "https://disease-ontology.org/term/DOID:3319", "evidence": [ { "id": "3319", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3319" } ], "weight": 0.0 }, { "disease_id": "DOID:3748", "name": "esophagus squamous cell carcinoma", "description": "An esophageal carcinoma that derives_from epithelial squamous cells located_in the esophagus.", "url": "https://disease-ontology.org/term/DOID:3748", "evidence": [ { "id": "3748", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3748" } ], "weight": 0.0 }, { "disease_id": "DOID:5409", "name": "lung small cell carcinoma", "description": "A lung carcinoma that has_material_basis_in primitive-appearing cells that are smaller than normal cells and is located_in the lung.", "url": "https://disease-ontology.org/term/DOID:5409", "evidence": [ { "id": "5409", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5409" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:8649", "name": "tongue cancer", "description": "", "url": "https://disease-ontology.org/term/DOID:8649", "evidence": [ { "id": "8649", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8649" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 } ], "biological_process": [ { "name": "TOR signaling", "id": "GO:0031929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031929", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNG4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNG4" } ], "pmid": "" }, { "name": "regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction", "id": "GO:0051896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051896", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNG4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNG4" } ], "pmid": "" }, { "name": "embryo development ending in birth or egg hatching", "id": "GO:0009792", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009792", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNG4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNG4" } ], "pmid": "" }, { "name": "lipid biosynthetic process", "id": "GO:0008610", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008610", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNG4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNG4" } ], "pmid": "" }, { "name": "positive regulation of cell migration", "id": "GO:0030335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030335", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNG4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNG4" } ], "pmid": "" }, { "name": "regulation of actin cytoskeleton organization", "id": "GO:0032956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032956", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNG4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNG4" } ], "pmid": "" }, { "name": "positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction", "id": "GO:0051897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051897", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNG4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNG4" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNG4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNG4" } ], "pmid": "" }, { "name": "positive regulation of endothelial cell proliferation", "id": "GO:0001938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001938", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNG4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNG4" } ], "pmid": "" }, { "name": "regulation of inflammatory response", "id": "GO:0050727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050727", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNG4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNG4" } ], "pmid": "" }, { "name": "positive regulation of peptidyl-tyrosine phosphorylation", "id": "GO:0050731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050731", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNG4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNG4" } ], "pmid": "" }, { "name": "positive regulation of TOR signaling", "id": "GO:0032008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032008", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNG4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNG4" } ], "pmid": "" }, { "name": "regulation of peptidyl-serine phosphorylation", "id": "GO:0033135", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033135", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNG4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNG4" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNG4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNG4" } ], "pmid": "" }, { "name": "regulation of protein phosphorylation", "id": "GO:0001932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001932", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNG4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNG4" } ], "pmid": "" }, { "name": "positive regulation of actin filament polymerization", "id": "GO:0030838", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030838", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNG4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNG4" } ], "pmid": "" }, { "name": "TORC2 signaling", "id": "GO:0038203", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038203", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNG4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNG4" } ], "pmid": "" }, { "name": "regulation of phosphorylation", "id": "GO:0042325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042325", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNG4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNG4" } ], "pmid": "" }, { "name": "regulation of establishment of cell polarity", "id": "GO:2000114", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000114", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNG4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNG4" } ], "pmid": "" } ], "cellular_component": [ { "name": "TORC2 complex", "id": "GO:0031932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031932", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNG4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNG4" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNG4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNG4" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNG4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNG4" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNG4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNG4" } ], "pmid": "" } ], "molecular_function": [ { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNG4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNG4" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNG4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNG4" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNG4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNG4" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNG4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNG4" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNG4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNG4" } ], "pmid": "" }, { "name": "ribosome binding", "id": "GO:0043022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043022", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNG4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNG4" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activator activity", "id": "GO:0043539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043539", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNG4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNG4" } ], "pmid": "" }, { "name": "enzyme-substrate adaptor activity", "id": "GO:0140767", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140767", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNG4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNG4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZNG4-1" }, { "uniprot_canonical_ac": "A0A0U1RRY2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A0U1RRY2", "url": "https://www.uniprot.org/uniprotkb/A0A0U1RRY2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 418, "chemical_mass": 47053.0, "gene_names": "Kctd20;Kctd20;RGD1309887", "protein_name": "", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A0U1RRY2", "url": "https://www.uniprot.org/uniprotkb/A0A0U1RRY2" } ], "pmid": "" } ], "molecular_function": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A0U1RRY2", "url": "https://www.uniprot.org/uniprotkb/A0A0U1RRY2" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of phosphorylation", "id": "GO:0042327", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042327", "evidence": [ { "database": "UniProtKB", "id": "A0A0U1RRY2", "url": "https://www.uniprot.org/uniprotkb/A0A0U1RRY2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A0U1RRY2-1" }, { "uniprot_canonical_ac": "A0A8I6A3F9-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A3F9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A3F9" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1031, "chemical_mass": 110587.0, "gene_names": "Zfp532;Zfp532;Znf532", "protein_name": "Zinc finger protein 532", "disease": [], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A3F9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A3F9" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A3F9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A3F9" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A3F9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A3F9" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A3F9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A3F9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6A3F9-1", "start_pos": "354", "end_pos": "354", "site_lbl": "Thr354", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 354, "start_aa": "Thr", "end_pos": 354, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr354", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6A3F9-1" }, { "uniprot_canonical_ac": "Q8K3R0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "Q8K3R0", "url": "https://www.uniprot.org/uniprotkb/Q8K3R0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 558, "chemical_mass": 61802.0, "gene_names": "Ces2a;Ces2i;Ces2j;Ces2a;Ces2j;Ces6;LOC246252", "protein_name": "Pyrethroid hydrolase Ces2a", "disease": [], "molecular_function": [ { "name": "trans-permethrin hydrolase activity", "id": "GO:0102209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0102209", "evidence": [ { "database": "UniProtKB", "id": "Q8K3R0", "url": "https://www.uniprot.org/uniprotkb/Q8K3R0" } ], "pmid": "" }, { "name": "retinyl-palmitate esterase activity", "id": "GO:0050253", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050253", "evidence": [ { "database": "UniProtKB", "id": "Q8K3R0", "url": "https://www.uniprot.org/uniprotkb/Q8K3R0" } ], "pmid": "" }, { "name": "all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity", "id": "GO:0047376", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047376", "evidence": [ { "database": "UniProtKB", "id": "Q8K3R0", "url": "https://www.uniprot.org/uniprotkb/Q8K3R0" } ], "pmid": "" }, { "name": "carboxylesterase activity", "id": "GO:0106435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106435", "evidence": [ { "database": "UniProtKB", "id": "Q8K3R0", "url": "https://www.uniprot.org/uniprotkb/Q8K3R0" } ], "pmid": "" }, { "name": "carboxylic ester hydrolase activity", "id": "GO:0052689", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052689", "evidence": [ { "database": "UniProtKB", "id": "Q8K3R0", "url": "https://www.uniprot.org/uniprotkb/Q8K3R0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q8K3R0-1", "start_pos": "116", "end_pos": "116", "site_lbl": "Thr116", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 116, "start_aa": "Thr", "end_pos": 116, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr116", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "Q8K3R0-1" }, { "uniprot_canonical_ac": "A0A8I6A116-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A116", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A116" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 782, "chemical_mass": 86783.0, "gene_names": "Fyb2", "protein_name": "FYN-binding protein 2", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A116", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A116" } ], "pmid": "" }, { "name": "membrane raft", "id": "GO:0045121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045121", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A116", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A116" } ], "pmid": "" }, { "name": "immunological synapse", "id": "GO:0001772", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001772", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A116", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A116" } ], "pmid": "" } ], "biological_process": [ { "name": "integrin-mediated signaling pathway", "id": "GO:0007229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007229", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A116", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A116" } ], "pmid": "" }, { "name": "protein localization to plasma membrane", "id": "GO:0072659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072659", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A116", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A116" } ], "pmid": "" }, { "name": "T cell receptor signaling pathway", "id": "GO:0050852", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050852", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A116", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A116" } ], "pmid": "" }, { "name": "cell adhesion mediated by integrin", "id": "GO:0033627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033627", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A116", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A116" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6A116-1", "start_pos": "743", "end_pos": "743", "site_lbl": "Thr743", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 743, "start_aa": "Thr", "end_pos": 743, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr743", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6A116-1" }, { "uniprot_canonical_ac": "A0A8I5ZW58-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZW58", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZW58" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1050, "chemical_mass": 117400.0, "gene_names": "Clec16a", "protein_name": "", "disease": [ { "disease_id": "DOID:1289", "name": "neurodegenerative disease", "description": "A central nervous system disease that results in the progressive deterioration of function or structure of neurons.", "url": "https://disease-ontology.org/term/DOID:1289", "evidence": [ { "id": "1289", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1289" } ], "weight": 0.0 }, { "disease_id": "DOID:13774", "name": "Addison's disease", "description": "An adrenal cortical hypofunction that is characterized by insufficient steroid hormone production by the adrenal glands.", "url": "https://disease-ontology.org/term/DOID:13774", "evidence": [ { "id": "13774", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13774" } ], "weight": 0.0 }, { "disease_id": "DOID:2377", "name": "multiple sclerosis", "description": "A demyelinating disease that involves damage to the fatty myelin sheaths around the axons of the brain and spinal cord resulting in demyelination and scarring.", "url": "https://disease-ontology.org/term/DOID:2377", "evidence": [ { "id": "2377", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2377" } ], "weight": 0.0 }, { "disease_id": "DOID:7148", "name": "rheumatoid arthritis", "description": "An arthritis that is an autoimmune disease which attacks healthy cells and tissue located_in joint.", "url": "https://disease-ontology.org/term/DOID:7148", "evidence": [ { "id": "7148", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7148" } ], "weight": 0.0 }, { "disease_id": "DOID:9744", "name": "type 1 diabetes mellitus", "description": "A diabetes mellitus that is characterized by destruction of pancreatic beta cells resulting in absent or extremely low insulin production.", "url": "https://disease-ontology.org/term/DOID:9744", "evidence": [ { "id": "9744", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9744" } ], "weight": 0.0 } ], "biological_process": [ { "name": "autophagy", "id": "GO:0006914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006914", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZW58", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZW58" } ], "pmid": "" }, { "name": "vacuolar transport", "id": "GO:0007034", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007034", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZW58", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZW58" } ], "pmid": "" }, { "name": "negative regulation of autophagosome maturation", "id": "GO:1901097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901097", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZW58", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZW58" } ], "pmid": "" }, { "name": "negative regulation of mitophagy", "id": "GO:1901525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901525", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZW58", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZW58" } ], "pmid": "" }, { "name": "positive regulation of TORC1 signaling", "id": "GO:1904263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904263", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZW58", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZW58" } ], "pmid": "" }, { "name": "endosomal transport", "id": "GO:0016197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016197", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZW58", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZW58" } ], "pmid": "" }, { "name": "positive regulation of autophagosome maturation", "id": "GO:1901098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901098", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZW58", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZW58" } ], "pmid": "" }, { "name": "cellular response to starvation", "id": "GO:0009267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009267", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZW58", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZW58" } ], "pmid": "" }, { "name": "mitophagy", "id": "GO:0000423", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000423", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZW58", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZW58" } ], "pmid": "" }, { "name": "protein destabilization", "id": "GO:0031648", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031648", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZW58", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZW58" } ], "pmid": "" }, { "name": "regulation of proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0032434", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032434", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZW58", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZW58" } ], "pmid": "" }, { "name": "negative regulation of proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0032435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032435", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZW58", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZW58" } ], "pmid": "" }, { "name": "regulation of autophagosome maturation", "id": "GO:1901096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901096", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZW58", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZW58" } ], "pmid": "" } ], "cellular_component": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZW58", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZW58" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZW58", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZW58" } ], "pmid": "" }, { "name": "vesicle", "id": "GO:0031982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031982", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZW58", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZW58" } ], "pmid": "" }, { "name": "endolysosome membrane", "id": "GO:0036020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036020", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZW58", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZW58" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZW58-1" }, { "uniprot_canonical_ac": "A0A8I6A9H1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A9H1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A9H1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1249, "chemical_mass": 132494.0, "gene_names": "C9h6orf132;C9h6orf132;RGD1561662", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6A9H1-1", "start_pos": "210", "end_pos": "210", "site_lbl": "Thr210", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 210, "start_aa": "Thr", "end_pos": 210, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr210", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I6A9H1-1", "start_pos": "308", "end_pos": "308", "site_lbl": "Thr308", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 308, "start_aa": "Thr", "end_pos": 308, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr308", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I6A9H1-1", "start_pos": "644", "end_pos": "644", "site_lbl": "Thr644", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 644, "start_aa": "Thr", "end_pos": 644, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr644", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I6A9H1-1", "start_pos": "664", "end_pos": "664", "site_lbl": "Thr664", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 664, "start_aa": "Thr", "end_pos": 664, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr664", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I6A9H1-1", "start_pos": "96", "end_pos": "96", "site_lbl": "Thr96", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 96, "start_aa": "Thr", "end_pos": 96, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr96", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6A9H1-1" }, { "uniprot_canonical_ac": "A0A8I5ZZ56-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZZ56", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZZ56" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 923, "chemical_mass": 105666.0, "gene_names": "Incenp", "protein_name": "Inner centromere protein", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZZ56", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZZ56" } ], "pmid": "" }, { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZZ56", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZZ56" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZZ56", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZZ56" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZZ56", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZZ56" } ], "pmid": "" }, { "name": "midbody", "id": "GO:0030496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030496", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZZ56", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZZ56" } ], "pmid": "" }, { "name": "central element", "id": "GO:0000801", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000801", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZZ56", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZZ56" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZZ56", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZZ56" } ], "pmid": "" }, { "name": "microtubule cytoskeleton", "id": "GO:0015630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015630", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZZ56", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZZ56" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZZ56", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZZ56" } ], "pmid": "" }, { "name": "chromosome, centromeric region", "id": "GO:0000775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000775", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZZ56", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZZ56" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZZ56", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZZ56" } ], "pmid": "" }, { "name": "chromosome passenger complex", "id": "GO:0032133", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032133", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZZ56", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZZ56" } ], "pmid": "" }, { "name": "pericentric heterochromatin", "id": "GO:0005721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005721", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZZ56", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZZ56" } ], "pmid": "" }, { "name": "chromocenter", "id": "GO:0010369", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010369", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZZ56", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZZ56" } ], "pmid": "" }, { "name": "lateral element", "id": "GO:0000800", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000800", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZZ56", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZZ56" } ], "pmid": "" }, { "name": "synaptonemal complex", "id": "GO:0000795", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000795", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZZ56", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZZ56" } ], "pmid": "" }, { "name": "meiotic spindle midzone", "id": "GO:1990385", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990385", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZZ56", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZZ56" } ], "pmid": "" } ], "biological_process": [ { "name": "chromosome segregation", "id": "GO:0007059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007059", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZZ56", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZZ56" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZZ56", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZZ56" } ], "pmid": "" }, { "name": "metaphase chromosome alignment", "id": "GO:0051310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051310", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZZ56", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZZ56" } ], "pmid": "" }, { "name": "mitotic cytokinesis", "id": "GO:0000281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000281", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZZ56", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZZ56" } ], "pmid": "" }, { "name": "meiotic spindle midzone assembly", "id": "GO:0051257", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051257", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZZ56", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZZ56" } ], "pmid": "" } ], "molecular_function": [ { "name": "molecular function activator activity", "id": "GO:0140677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140677", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZZ56", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZZ56" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZZ56-1" }, { "uniprot_canonical_ac": "A0A8I5ZQ14-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQ14", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQ14" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 763, "chemical_mass": 84279.0, "gene_names": "Afg3l1", "protein_name": "", "disease": [ { "disease_id": "DOID:0050977", "name": "spinocerebellar ataxia 28", "description": "An autosomal dominant cerebellar ataxia that is characterized by progressive ataxia, dysarthria, hyperreflexia, ophthalmoparesis, nystagmus and ptosis, and has_material_basis_in mutation in the AFG3L2 gene.", "url": "https://disease-ontology.org/term/DOID:0050977", "evidence": [ { "id": "0050977", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050977" } ], "weight": 0.0 }, { "disease_id": "DOID:0080840", "name": "optic atrophy 12", "description": "An optic atrophy that is characterized by slowly progressive visual impairment with onset usually in the first decade and that has_material_basis_in heterozygous mutation in the AFG3L2 gene on chromosome 18p11.", "url": "https://disease-ontology.org/term/DOID:0080840", "evidence": [ { "id": "0080840", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080840" } ], "weight": 0.0 }, { "disease_id": "DOID:1289", "name": "neurodegenerative disease", "description": "A central nervous system disease that results in the progressive deterioration of function or structure of neurons.", "url": "https://disease-ontology.org/term/DOID:1289", "evidence": [ { "id": "1289", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1289" } ], "weight": 0.0 }, { "disease_id": "DOID:2476", "name": "hereditary spastic paraplegia", "description": "A paraplegia that is characterized by progressive stiffness and contraction (spasticity) in the lower limbs.", "url": "https://disease-ontology.org/term/DOID:2476", "evidence": [ { "id": "2476", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2476" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "metalloendopeptidase activity", "id": "GO:0004222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004222", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQ14", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQ14" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQ14", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQ14" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQ14", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQ14" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQ14", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQ14" } ], "pmid": "" }, { "name": "ATP-dependent peptidase activity", "id": "GO:0004176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004176", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQ14", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQ14" } ], "pmid": "" } ], "cellular_component": [ { "name": "m-AAA complex", "id": "GO:0005745", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005745", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQ14", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQ14" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQ14", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQ14" } ], "pmid": "" } ], "biological_process": [ { "name": "mitochondrial fusion", "id": "GO:0008053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008053", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQ14", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQ14" } ], "pmid": "" }, { "name": "mitochondrial protein processing", "id": "GO:0034982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034982", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQ14", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQ14" } ], "pmid": "" }, { "name": "cristae formation", "id": "GO:0042407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042407", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQ14", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQ14" } ], "pmid": "" }, { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQ14", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQ14" } ], "pmid": "" }, { "name": "protein maturation", "id": "GO:0051604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051604", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQ14", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQ14" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZQ14-1" }, { "uniprot_canonical_ac": "A0A8I5XVM7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XVM7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XVM7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 158, "chemical_mass": 17486.0, "gene_names": "Ociad2", "protein_name": "", "disease": [], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XVM7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XVM7" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XVM7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XVM7" } ], "pmid": "" }, { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XVM7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XVM7" } ], "pmid": "" } ], "biological_process": [ { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XVM7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XVM7" } ], "pmid": "" }, { "name": "response to bacterium", "id": "GO:0009617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009617", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XVM7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XVM7" } ], "pmid": "" }, { "name": "mitochondrial respiratory chain complex III assembly", "id": "GO:0034551", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034551", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XVM7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XVM7" } ], "pmid": "" }, { "name": "regulation of stem cell differentiation", "id": "GO:2000736", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000736", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XVM7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XVM7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5XVM7-1" }, { "uniprot_canonical_ac": "A0A8I5ZKA9-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZKA9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZKA9" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 632, "chemical_mass": 71394.0, "gene_names": "Abcd4", "protein_name": "", "disease": [], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZKA9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZKA9" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZKA9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZKA9" } ], "pmid": "" }, { "name": "ABC-type transporter activity", "id": "GO:0140359", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140359", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZKA9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZKA9" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZKA9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZKA9" } ], "pmid": "" }, { "name": "ABC-type vitamin B12 transporter activity", "id": "GO:0015420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015420", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZKA9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZKA9" } ], "pmid": "" } ], "cellular_component": [ { "name": "organelle membrane", "id": "GO:0031090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031090", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZKA9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZKA9" } ], "pmid": "" }, { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZKA9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZKA9" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZKA9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZKA9" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZKA9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZKA9" } ], "pmid": "" } ], "biological_process": [ { "name": "cellular response to leukemia inhibitory factor", "id": "GO:1990830", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990830", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZKA9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZKA9" } ], "pmid": "" }, { "name": "cobalamin metabolic process", "id": "GO:0009235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009235", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZKA9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZKA9" } ], "pmid": "" }, { "name": "cobalamin transport", "id": "GO:0015889", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015889", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZKA9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZKA9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I5ZKA9-1", "start_pos": "7", "end_pos": "7", "site_lbl": "Thr7", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 7, "start_aa": "Thr", "end_pos": 7, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr7", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I5ZKA9-1" }, { "uniprot_canonical_ac": "A0A8I6A122-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A122", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A122" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 186, "chemical_mass": 20887.0, "gene_names": "Tbpl1;Tbpl1", "protein_name": "TATA box-binding protein-like 1", "disease": [], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A122", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A122" } ], "pmid": "" }, { "name": "RNA polymerase II core promoter sequence-specific DNA binding", "id": "GO:0000979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000979", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A122", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A122" } ], "pmid": "" }, { "name": "RNA polymerase II general transcription initiation factor activity", "id": "GO:0016251", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016251", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A122", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A122" } ], "pmid": "" }, { "name": "general transcription initiation factor activity", "id": "GO:0140223", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140223", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A122", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A122" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A122", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A122" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A122", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A122" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A122", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A122" } ], "pmid": "" }, { "name": "transcription factor TFIIA complex", "id": "GO:0005672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005672", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A122", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A122" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription initiation", "id": "GO:0006352", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006352", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A122", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A122" } ], "pmid": "" }, { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A122", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A122" } ], "pmid": "" }, { "name": "acrosome assembly", "id": "GO:0001675", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001675", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A122", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A122" } ], "pmid": "" }, { "name": "spermatid nucleus differentiation", "id": "GO:0007289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007289", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A122", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A122" } ], "pmid": "" }, { "name": "dTTP biosynthetic process", "id": "GO:0006235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006235", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A122", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A122" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6A122-1", "start_pos": "144", "end_pos": "144", "site_lbl": "Ser144", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 144, "start_aa": "Ser", "end_pos": 144, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser144", "evidence": [ { "id": "26446791", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/26446791" }, { "id": "A0A8I6A122", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/A0A8I6A122" } ] } ] } ], "record_id": "A0A8I6A122-1" }, { "uniprot_canonical_ac": "A0A8I6AAD8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AAD8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AAD8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 461, "chemical_mass": 52992.0, "gene_names": "Snx4", "protein_name": "Sorting nexin-4", "disease": [], "molecular_function": [ { "name": "insulin receptor binding", "id": "GO:0005158", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005158", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AAD8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AAD8" } ], "pmid": "" }, { "name": "epidermal growth factor receptor binding", "id": "GO:0005154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005154", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AAD8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AAD8" } ], "pmid": "" }, { "name": "phosphatidylinositol-3-phosphate binding", "id": "GO:0032266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032266", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AAD8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AAD8" } ], "pmid": "" }, { "name": "phosphatidylinositol binding", "id": "GO:0035091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035091", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AAD8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AAD8" } ], "pmid": "" }, { "name": "leptin receptor binding", "id": "GO:1990460", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990460", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AAD8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AAD8" } ], "pmid": "" }, { "name": "transferrin receptor binding", "id": "GO:1990459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990459", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AAD8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AAD8" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AAD8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AAD8" } ], "pmid": "" }, { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AAD8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AAD8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AAD8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AAD8" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AAD8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AAD8" } ], "pmid": "" }, { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AAD8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AAD8" } ], "pmid": "" }, { "name": "presynaptic endosome", "id": "GO:0098830", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098830", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AAD8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AAD8" } ], "pmid": "" }, { "name": "cytoplasmic dynein complex", "id": "GO:0005868", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005868", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AAD8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AAD8" } ], "pmid": "" }, { "name": "SNARE complex", "id": "GO:0031201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031201", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AAD8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AAD8" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AAD8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AAD8" } ], "pmid": "" } ], "biological_process": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AAD8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AAD8" } ], "pmid": "" }, { "name": "endocytic recycling", "id": "GO:0032456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032456", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AAD8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AAD8" } ], "pmid": "" }, { "name": "positive regulation of histamine secretion by mast cell", "id": "GO:1903595", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903595", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AAD8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AAD8" } ], "pmid": "" }, { "name": "positive regulation of autophagosome assembly", "id": "GO:2000786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000786", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AAD8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AAD8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AAD8-1" }, { "uniprot_canonical_ac": "A0A8I6AS60-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AS60", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AS60" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 639, "chemical_mass": 69438.0, "gene_names": "Eya4;Eya4", "protein_name": "Eyes absent homolog", "disease": [ { "disease_id": "DOID:0110440", "name": "dilated cardiomyopathy 1J", "description": "A dilated cardiomyopathy that has_material_basis_in mutation in the EYA4 gene on chromosome 6q23.2.", "url": "https://disease-ontology.org/term/DOID:0110440", "evidence": [ { "id": "0110440", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110440" } ], "weight": 0.0 }, { "disease_id": "DOID:0110542", "name": "autosomal dominant nonsyndromic deafness 10", "description": "An autosomal dominant nonsyndromic deafness that is characterized by postlingual onset in the third or forth decade of life with a flat or gently downsloping audioprofiles and has_material_basis_in mutation in the EYA4 gene on chromosome 6q23.", "url": "https://disease-ontology.org/term/DOID:0110542", "evidence": [ { "id": "0110542", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110542" } ], "weight": 0.0 }, { "disease_id": "DOID:10003", "name": "sensorineural hearing loss", "description": "An inner ear disease that is characterized by hearing loss resulting from damage to the cochlea, auditory nerve and/or brainstem.", "url": "https://disease-ontology.org/term/DOID:10003", "evidence": [ { "id": "10003", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10003" } ], "weight": 0.0 }, { "disease_id": "DOID:10754", "name": "otitis media", "description": "A otitis which involves inflammation of the middle ear.", "url": "https://disease-ontology.org/term/DOID:10754", "evidence": [ { "id": "10754", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10754" } ], "weight": 0.0 }, { "disease_id": "DOID:12930", "name": "dilated cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by an an enlarged heart and damage to the myocardium causing the heart to pump blood inefficiently.", "url": "https://disease-ontology.org/term/DOID:12930", "evidence": [ { "id": "12930", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12930" } ], "weight": 0.0 }, { "disease_id": "DOID:14702", "name": "branchiootorenal syndrome", "description": "A syndrome characterized by branchial arch anomalies (branchial fistulas, clefts, or cysts), hearing impairment, structural defects of the outer, middle, and inner ear, and renal abnormalities.", "url": "https://disease-ontology.org/term/DOID:14702", "evidence": [ { "id": "14702", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14702" } ], "weight": 0.0 }, { "disease_id": "DOID:5614", "name": "eye disease", "description": "An eye and adnexa disease that is located_in the eye.", "url": "https://disease-ontology.org/term/DOID:5614", "evidence": [ { "id": "5614", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5614" } ], "weight": 0.0 }, { "disease_id": "DOID:6000", "name": "congestive heart failure", "description": "A heart disease that is characterized by any structural or functional cardiac disorder that impairs the ability of the heart to fill with or pump a sufficient amount of blood throughout the body.", "url": "https://disease-ontology.org/term/DOID:6000", "evidence": [ { "id": "6000", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6000" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AS60", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AS60" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AS60", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AS60" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AS60", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AS60" } ], "pmid": "" }, { "name": "sensory perception of sound", "id": "GO:0007605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007605", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AS60", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AS60" } ], "pmid": "" }, { "name": "middle ear morphogenesis", "id": "GO:0042474", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042474", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AS60", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AS60" } ], "pmid": "" }, { "name": "inner ear development", "id": "GO:0048839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048839", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AS60", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AS60" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AS60", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AS60" } ], "pmid": "" }, { "name": "positive regulation of DNA repair", "id": "GO:0045739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045739", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AS60", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AS60" } ], "pmid": "" }, { "name": "negative regulation of extrinsic apoptotic signaling pathway in absence of ligand", "id": "GO:2001240", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001240", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AS60", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AS60" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AS60", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AS60" } ], "pmid": "" }, { "name": "protein tyrosine phosphatase activity", "id": "GO:0004725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004725", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AS60", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AS60" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AS60-1" }, { "uniprot_canonical_ac": "A0A8I5ZM18-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZM18", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZM18" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 431, "chemical_mass": 47866.0, "gene_names": "Tmprss11c;Hatl3;Tmprss11b;Tmprss11c", "protein_name": "Transmembrane protease serine", "disease": [], "molecular_function": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZM18", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZM18" } ], "pmid": "" }, { "name": "serine-type peptidase activity", "id": "GO:0008236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008236", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZM18", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZM18" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZM18", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZM18" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZM18", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZM18" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZM18", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZM18" } ], "pmid": "" }, { "name": "perikaryon", "id": "GO:0043204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043204", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZM18", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZM18" } ], "pmid": "" } ], "biological_process": [ { "name": "protein processing", "id": "GO:0016485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016485", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZM18", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZM18" } ], "pmid": "" }, { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZM18", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZM18" } ], "pmid": "" }, { "name": "self proteolysis", "id": "GO:0097264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097264", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZM18", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZM18" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I5ZM18-1", "start_pos": "194", "end_pos": "194", "site_lbl": "Thr194", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 194, "start_aa": "Thr", "end_pos": 194, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr194", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I5ZM18-1" }, { "uniprot_canonical_ac": "A0A8I5ZNR8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNR8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNR8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1978, "chemical_mass": 226691.0, "gene_names": "Dock4;Dock4", "protein_name": "Dedicator of cytokinesis protein 4", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNR8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNR8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNR8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNR8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNR8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNR8" } ], "pmid": "" }, { "name": "organelle", "id": "GO:0043226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043226", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNR8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNR8" } ], "pmid": "" }, { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNR8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNR8" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNR8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNR8" } ], "pmid": "" }, { "name": "postsynapse", "id": "GO:0098794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098794", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNR8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNR8" } ], "pmid": "" }, { "name": "stereocilium bundle", "id": "GO:0032421", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032421", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNR8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNR8" } ], "pmid": "" }, { "name": "stereocilium", "id": "GO:0032420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032420", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNR8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNR8" } ], "pmid": "" } ], "molecular_function": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNR8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNR8" } ], "pmid": "" }, { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNR8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNR8" } ], "pmid": "" }, { "name": "SH3 domain binding", "id": "GO:0017124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017124", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNR8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNR8" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNR8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNR8" } ], "pmid": "" }, { "name": "PDZ domain binding", "id": "GO:0030165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030165", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNR8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNR8" } ], "pmid": "" }, { "name": "receptor tyrosine kinase binding", "id": "GO:0030971", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030971", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNR8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNR8" } ], "pmid": "" } ], "biological_process": [ { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNR8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNR8" } ], "pmid": "" }, { "name": "cell chemotaxis", "id": "GO:0060326", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060326", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNR8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNR8" } ], "pmid": "" }, { "name": "positive regulation of vascular associated smooth muscle cell migration", "id": "GO:1904754", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904754", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNR8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNR8" } ], "pmid": "" }, { "name": "negative regulation of vascular associated smooth muscle contraction", "id": "GO:1904694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904694", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNR8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNR8" } ], "pmid": "" }, { "name": "regulation of postsynapse assembly", "id": "GO:0150052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0150052", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNR8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNR8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I5ZNR8-1", "start_pos": "1738", "end_pos": "1738", "site_lbl": "Thr1738", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1738, "start_aa": "Thr", "end_pos": 1738, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1738", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I5ZNR8-1", "start_pos": "1773", "end_pos": "1773", "site_lbl": "Thr1773", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1773, "start_aa": "Thr", "end_pos": 1773, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1773", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I5ZNR8-1" }, { "uniprot_canonical_ac": "A0A8I5ZYJ1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYJ1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 3266, "chemical_mass": 348753.0, "gene_names": "Srcap;RGD1565642;Srcap", "protein_name": "", "disease": [ { "disease_id": "DOID:0050888", "name": "syndromic intellectual disability", "description": "An intellectual disability that is characterized by the presence of associated medical and behavioral sign and symptoms.", "url": "https://disease-ontology.org/term/DOID:0050888", "evidence": [ { "id": "0050888", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050888" } ], "weight": 0.0 }, { "disease_id": "DOID:0060037", "name": "developmental disorder of mental health", "description": "A disease of mental health that occur during a child's developmental period between birth and age 18 resulting in retarding of the child's psychological or physical development.", "url": "https://disease-ontology.org/term/DOID:0060037", "evidence": [ { "id": "0060037", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060037" } ], "weight": 0.0 }, { "disease_id": "DOID:0111358", "name": "Floating-Harbor syndrome", "description": "A syndrome characterized by growth retardation, proportionate short stature, delayed bone age, delayed speech development and facial features including triangular shape, deep-set eyes, long eyelashes, bulbous nose, wide columella, short philtrum, and thin lips that has_material_basis_in heterozygous mutation in the SRCAP gene on chromosome 16p11.2.", "url": "https://disease-ontology.org/term/DOID:0111358", "evidence": [ { "id": "0111358", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111358" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYJ1" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYJ1" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYJ1" } ], "pmid": "" }, { "name": "helicase activity", "id": "GO:0004386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004386", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYJ1" } ], "pmid": "" }, { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYJ1" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYJ1" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYJ1" } ], "pmid": "" }, { "name": "catalytic activity, acting on a protein", "id": "GO:0140096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140096", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYJ1" } ], "pmid": "" }, { "name": "ATP-dependent chromatin remodeler activity", "id": "GO:0140658", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140658", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYJ1" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYJ1" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYJ1" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYJ1" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYJ1" } ], "pmid": "" }, { "name": "Swr1 complex", "id": "GO:0000812", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000812", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYJ1" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYJ1" } ], "pmid": "" } ], "biological_process": [ { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYJ1" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYJ1" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYJ1" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYJ1" } ], "pmid": "" }, { "name": "cAMP/PKA signal transduction", "id": "GO:0141156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141156", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYJ1" } ], "pmid": "" }, { "name": "positive regulation of macromolecule biosynthetic process", "id": "GO:0010557", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010557", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYJ1" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYJ1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I5ZYJ1-1", "start_pos": "1274", "end_pos": "1274", "site_lbl": "Thr1274", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1274, "start_aa": "Thr", "end_pos": 1274, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1274", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I5ZYJ1-1", "start_pos": "1278", "end_pos": "1278", "site_lbl": "Thr1278", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1278, "start_aa": "Thr", "end_pos": 1278, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1278", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I5ZYJ1-1", "start_pos": "1374", "end_pos": "1374", "site_lbl": "Thr1374", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1374, "start_aa": "Thr", "end_pos": 1374, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1374", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I5ZYJ1-1", "start_pos": "1609", "end_pos": "1609", "site_lbl": "Thr1609", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1609, "start_aa": "Thr", "end_pos": 1609, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1609", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I5ZYJ1-1", "start_pos": "1723", "end_pos": "1723", "site_lbl": "Thr1723", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1723, "start_aa": "Thr", "end_pos": 1723, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1723", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I5ZYJ1-1", "start_pos": "1739", "end_pos": "1739", "site_lbl": "Thr1739", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1739, "start_aa": "Thr", "end_pos": 1739, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1739", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I5ZYJ1-1", "start_pos": "2548", "end_pos": "2548", "site_lbl": "Thr2548", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2548, "start_aa": "Thr", "end_pos": 2548, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2548", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I5ZYJ1-1", "start_pos": "579", "end_pos": "579", "site_lbl": "Thr579", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 579, "start_aa": "Thr", "end_pos": 579, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr579", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I5ZYJ1-1", "start_pos": "583", "end_pos": "583", "site_lbl": "Thr583", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 583, "start_aa": "Thr", "end_pos": 583, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr583", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I5ZYJ1-1", "start_pos": "926", "end_pos": "926", "site_lbl": "Thr926", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 926, "start_aa": "Thr", "end_pos": 926, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr926", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I5ZYJ1-1" }, { "uniprot_canonical_ac": "A0A8I5ZTN7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTN7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTN7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 604, "chemical_mass": 68984.0, "gene_names": "Gbp5", "protein_name": "", "disease": [], "molecular_function": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTN7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTN7" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTN7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTN7" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTN7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTN7" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTN7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTN7" } ], "pmid": "" }, { "name": "molecular function inhibitor activity", "id": "GO:0140678", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140678", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTN7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTN7" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTN7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTN7" } ], "pmid": "" }, { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTN7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTN7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTN7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTN7" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTN7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTN7" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTN7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTN7" } ], "pmid": "" }, { "name": "symbiont cell surface", "id": "GO:0106139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106139", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTN7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTN7" } ], "pmid": "" } ], "biological_process": [ { "name": "cellular response to type II interferon", "id": "GO:0071346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071346", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTN7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTN7" } ], "pmid": "" }, { "name": "regulation of defense response", "id": "GO:0031347", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031347", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTN7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTN7" } ], "pmid": "" }, { "name": "positive regulation of interleukin-18 production", "id": "GO:0032741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032741", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTN7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTN7" } ], "pmid": "" }, { "name": "protein homotetramerization", "id": "GO:0051289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051289", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTN7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTN7" } ], "pmid": "" }, { "name": "defense response to virus", "id": "GO:0051607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051607", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTN7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTN7" } ], "pmid": "" }, { "name": "protein targeting", "id": "GO:0006605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006605", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTN7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTN7" } ], "pmid": "" }, { "name": "response to bacterium", "id": "GO:0009617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009617", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTN7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTN7" } ], "pmid": "" }, { "name": "cellular response to lipopolysaccharide", "id": "GO:0071222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071222", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTN7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTN7" } ], "pmid": "" }, { "name": "defense response to bacterium", "id": "GO:0042742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042742", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTN7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTN7" } ], "pmid": "" }, { "name": "activation of innate immune response", "id": "GO:0002218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002218", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTN7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTN7" } ], "pmid": "" }, { "name": "positive regulation of interleukin-1 beta production", "id": "GO:0032731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032731", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTN7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTN7" } ], "pmid": "" }, { "name": "protein localization to Golgi apparatus", "id": "GO:0034067", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034067", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTN7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTN7" } ], "pmid": "" }, { "name": "positive regulation of innate immune response", "id": "GO:0045089", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045089", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTN7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTN7" } ], "pmid": "" }, { "name": "positive regulation of NLRP3 inflammasome complex assembly", "id": "GO:1900227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900227", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTN7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTN7" } ], "pmid": "" }, { "name": "positive regulation of cytokine production involved in inflammatory response", "id": "GO:1900017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900017", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTN7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTN7" } ], "pmid": "" }, { "name": "cytolysis in another organism", "id": "GO:0051715", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051715", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTN7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTN7" } ], "pmid": "" }, { "name": "positive regulation of AIM2 inflammasome complex assembly", "id": "GO:0140973", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140973", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTN7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTN7" } ], "pmid": "" }, { "name": "positive regulation of pyroptotic inflammatory response", "id": "GO:0140639", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140639", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTN7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTN7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZTN7-1" }, { "uniprot_canonical_ac": "A0A8I5ZT33-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZT33", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZT33" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 651, "chemical_mass": 70909.0, "gene_names": "Vit;RGD1564128;Vit", "protein_name": "Vitrin", "disease": [], "biological_process": [ { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZT33", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZT33" } ], "pmid": "" }, { "name": "spinal cord development", "id": "GO:0021510", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021510", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZT33", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZT33" } ], "pmid": "" }, { "name": "extracellular matrix organization", "id": "GO:0030198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030198", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZT33", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZT33" } ], "pmid": "" }, { "name": "positive regulation of cell-substrate adhesion", "id": "GO:0010811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010811", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZT33", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZT33" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZT33", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZT33" } ], "pmid": "" }, { "name": "interstitial matrix", "id": "GO:0005614", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005614", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZT33", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZT33" } ], "pmid": "" } ], "molecular_function": [ { "name": "glycosaminoglycan binding", "id": "GO:0005539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005539", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZT33", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZT33" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZT33-1" }, { "uniprot_canonical_ac": "A0A8I5XZV4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XZV4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XZV4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1267, "chemical_mass": 140394.0, "gene_names": "Zmynd8", "protein_name": "", "disease": [ { "disease_id": "DOID:0050888", "name": "syndromic intellectual disability", "description": "An intellectual disability that is characterized by the presence of associated medical and behavioral sign and symptoms.", "url": "https://disease-ontology.org/term/DOID:0050888", "evidence": [ { "id": "0050888", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050888" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XZV4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XZV4" } ], "pmid": "" }, { "name": "protein domain specific binding", "id": "GO:0019904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019904", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XZV4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XZV4" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XZV4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XZV4" } ], "pmid": "" }, { "name": "histone H3K14ac reader activity", "id": "GO:0140015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140015", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XZV4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XZV4" } ], "pmid": "" }, { "name": "histone H3K4me1 reader activity", "id": "GO:0140109", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140109", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XZV4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XZV4" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XZV4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XZV4" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XZV4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XZV4" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XZV4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XZV4" } ], "pmid": "" }, { "name": "modulation of excitatory postsynaptic potential", "id": "GO:0098815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098815", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XZV4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XZV4" } ], "pmid": "" }, { "name": "negative regulation of cell migration", "id": "GO:0030336", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030336", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XZV4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XZV4" } ], "pmid": "" }, { "name": "double-strand break repair via homologous recombination", "id": "GO:0000724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000724", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XZV4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XZV4" } ], "pmid": "" }, { "name": "positive regulation of filopodium assembly", "id": "GO:0051491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051491", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XZV4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XZV4" } ], "pmid": "" }, { "name": "positive regulation of dendritic spine development", "id": "GO:0060999", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060999", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XZV4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XZV4" } ], "pmid": "" }, { "name": "positive regulation of dendritic spine maintenance", "id": "GO:1902952", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902952", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XZV4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XZV4" } ], "pmid": "" }, { "name": "positive regulation of transcription elongation by RNA polymerase II", "id": "GO:0032968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032968", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XZV4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XZV4" } ], "pmid": "" }, { "name": "regulation of postsynaptic density protein 95 clustering", "id": "GO:1902897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902897", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XZV4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XZV4" } ], "pmid": "" }, { "name": "protein localization to chromatin", "id": "GO:0071168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071168", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XZV4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XZV4" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XZV4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XZV4" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XZV4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XZV4" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XZV4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XZV4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XZV4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XZV4" } ], "pmid": "" }, { "name": "dendritic spine", "id": "GO:0043197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043197", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XZV4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XZV4" } ], "pmid": "" }, { "name": "dendritic shaft", "id": "GO:0043198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043198", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XZV4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XZV4" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XZV4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XZV4" } ], "pmid": "" }, { "name": "site of DNA damage", "id": "GO:0090734", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090734", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5XZV4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5XZV4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I5XZV4-1", "start_pos": "783", "end_pos": "783", "site_lbl": "Thr783", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" }, { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "reported site T772 is on non-canonical isoform A0A8I6A294-1 which maps to canonical isoform site A0A8I5XZV4-1:783", "icn3d_view": {}, "start_pos": 783, "start_aa": "Thr", "end_pos": 783, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr783", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I5XZV4-1" }, { "uniprot_canonical_ac": "A0A8I6A6B6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A6B6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A6B6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 977, "chemical_mass": 109451.0, "gene_names": "Ppp1r12b;Ppp1r12b", "protein_name": "Protein phosphatase 1 regulatory subunit", "disease": [], "biological_process": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A6B6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A6B6" } ], "pmid": "" }, { "name": "neuron projection morphogenesis", "id": "GO:0048812", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048812", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A6B6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A6B6" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A6B6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A6B6" } ], "pmid": "" }, { "name": "phosphatase regulator activity", "id": "GO:0019208", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019208", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A6B6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A6B6" } ], "pmid": "" }, { "name": "myosin phosphatase regulator activity", "id": "GO:0017020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017020", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A6B6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A6B6" } ], "pmid": "" }, { "name": "enzyme inhibitor activity", "id": "GO:0004857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004857", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A6B6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A6B6" } ], "pmid": "" } ], "cellular_component": [ { "name": "stress fiber", "id": "GO:0001725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001725", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A6B6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A6B6" } ], "pmid": "" }, { "name": "Z disc", "id": "GO:0030018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030018", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A6B6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A6B6" } ], "pmid": "" }, { "name": "A band", "id": "GO:0031672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031672", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A6B6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A6B6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A6B6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A6B6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6A6B6-1" }, { "uniprot_canonical_ac": "A0A0G2K4D6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K4D6", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K4D6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 723, "chemical_mass": 83854.0, "gene_names": "Rufy2", "protein_name": "", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K4D6", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K4D6" } ], "pmid": "" } ], "molecular_function": [ { "name": "SH3 domain binding", "id": "GO:0017124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017124", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K4D6", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K4D6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A0G2K4D6-1" }, { "uniprot_canonical_ac": "P0DX21-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "P0DX21", "url": "https://www.uniprot.org/uniprotkb/P0DX21" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 447, "chemical_mass": 48638.0, "gene_names": "Slc17a9;RGD1311940;Slc17a9;VNUT", "protein_name": "Voltage-gated purine nucleotide uniporter SLC17A9", "disease": [ { "disease_id": "DOID:3805", "name": "porokeratosis", "description": "", "url": "https://disease-ontology.org/term/DOID:3805", "evidence": [ { "id": "3805", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3805" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "secretory granule", "id": "GO:0030141", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030141", "evidence": [ { "database": "UniProtKB", "id": "P0DX21", "url": "https://www.uniprot.org/uniprotkb/P0DX21" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "P0DX21", "url": "https://www.uniprot.org/uniprotkb/P0DX21" } ], "pmid": "" }, { "name": "transport vesicle membrane", "id": "GO:0030658", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030658", "evidence": [ { "database": "UniProtKB", "id": "P0DX21", "url": "https://www.uniprot.org/uniprotkb/P0DX21" } ], "pmid": "" }, { "name": "chromaffin granule membrane", "id": "GO:0042584", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042584", "evidence": [ { "database": "UniProtKB", "id": "P0DX21", "url": "https://www.uniprot.org/uniprotkb/P0DX21" } ], "pmid": "" }, { "name": "mucin granule", "id": "GO:0098594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098594", "evidence": [ { "database": "UniProtKB", "id": "P0DX21", "url": "https://www.uniprot.org/uniprotkb/P0DX21" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "P0DX21", "url": "https://www.uniprot.org/uniprotkb/P0DX21" } ], "pmid": "" } ], "biological_process": [ { "name": "ADP transport", "id": "GO:0015866", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015866", "evidence": [ { "database": "UniProtKB", "id": "P0DX21", "url": "https://www.uniprot.org/uniprotkb/P0DX21" } ], "pmid": "" }, { "name": "lysosomal protein catabolic process", "id": "GO:1905146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905146", "evidence": [ { "database": "UniProtKB", "id": "P0DX21", "url": "https://www.uniprot.org/uniprotkb/P0DX21" } ], "pmid": "" }, { "name": "guanine nucleotide transmembrane transport", "id": "GO:1903790", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903790", "evidence": [ { "database": "UniProtKB", "id": "P0DX21", "url": "https://www.uniprot.org/uniprotkb/P0DX21" } ], "pmid": "" }, { "name": "ATP transport", "id": "GO:0015867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015867", "evidence": [ { "database": "UniProtKB", "id": "P0DX21", "url": "https://www.uniprot.org/uniprotkb/P0DX21" } ], "pmid": "" }, { "name": "ATP export", "id": "GO:1904669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904669", "evidence": [ { "database": "UniProtKB", "id": "P0DX21", "url": "https://www.uniprot.org/uniprotkb/P0DX21" } ], "pmid": "" }, { "name": "purine nucleotide import into lysosome", "id": "GO:0141013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141013", "evidence": [ { "database": "UniProtKB", "id": "P0DX21", "url": "https://www.uniprot.org/uniprotkb/P0DX21" } ], "pmid": "" } ], "molecular_function": [ { "name": "ATP transmembrane transporter activity", "id": "GO:0005347", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005347", "evidence": [ { "database": "UniProtKB", "id": "P0DX21", "url": "https://www.uniprot.org/uniprotkb/P0DX21" } ], "pmid": "" }, { "name": "ADP transmembrane transporter activity", "id": "GO:0015217", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015217", "evidence": [ { "database": "UniProtKB", "id": "P0DX21", "url": "https://www.uniprot.org/uniprotkb/P0DX21" } ], "pmid": "" }, { "name": "guanine nucleotide transmembrane transporter activity", "id": "GO:0001409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001409", "evidence": [ { "database": "UniProtKB", "id": "P0DX21", "url": "https://www.uniprot.org/uniprotkb/P0DX21" } ], "pmid": "" }, { "name": "purine nucleotide uniporter activity", "id": "GO:0160042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160042", "evidence": [ { "database": "UniProtKB", "id": "P0DX21", "url": "https://www.uniprot.org/uniprotkb/P0DX21" } ], "pmid": "" }, { "name": "secondary active transmembrane transporter activity", "id": "GO:0015291", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015291", "evidence": [ { "database": "UniProtKB", "id": "P0DX21", "url": "https://www.uniprot.org/uniprotkb/P0DX21" } ], "pmid": "" }, { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "P0DX21", "url": "https://www.uniprot.org/uniprotkb/P0DX21" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P0DX21-1" }, { "uniprot_canonical_ac": "A0A8I5ZYV7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYV7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYV7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 312, "chemical_mass": 34683.0, "gene_names": "Mrpl21", "protein_name": "Large ribosomal subunit protein bL21m", "disease": [], "cellular_component": [ { "name": "mitochondrial large ribosomal subunit", "id": "GO:0005762", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005762", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYV7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYV7" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYV7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYV7" } ], "pmid": "" } ], "molecular_function": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYV7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYV7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZYV7-1" }, { "uniprot_canonical_ac": "A0A8I5ZLL3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZLL3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZLL3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1402, "chemical_mass": 155803.0, "gene_names": "Arhgef18", "protein_name": "", "disease": [ { "disease_id": "DOID:0061113", "name": "retinitis pigmentosa 78", "description": "A retinitis pigmentosa characterized by central visual disturbance, visual field defects, and nyctalopia that has_material_basis_in homozygous or compound heterozygous mutation in the ARHGEF18 gene on chromosome 19p13.", "url": "https://disease-ontology.org/term/DOID:0061113", "evidence": [ { "id": "0061113", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061113" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZLL3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZLL3" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZLL3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZLL3" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZLL3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZLL3" } ], "pmid": "" }, { "name": "apical part of cell", "id": "GO:0045177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045177", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZLL3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZLL3" } ], "pmid": "" } ], "molecular_function": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZLL3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZLL3" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZLL3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZLL3" } ], "pmid": "" } ], "biological_process": [ { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZLL3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZLL3" } ], "pmid": "" }, { "name": "protein localization to cell-cell junction", "id": "GO:0150105", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0150105", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZLL3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZLL3" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZLL3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZLL3" } ], "pmid": "" }, { "name": "regulation of cell shape", "id": "GO:0008360", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008360", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZLL3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZLL3" } ], "pmid": "" }, { "name": "negative regulation of stress fiber assembly", "id": "GO:0051497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051497", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZLL3", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZLL3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I5ZLL3-1", "start_pos": "170", "end_pos": "170", "site_lbl": "Thr170", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 170, "start_aa": "Thr", "end_pos": 170, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr170", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I5ZLL3-1", "start_pos": "393", "end_pos": "393", "site_lbl": "Thr393", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 393, "start_aa": "Thr", "end_pos": 393, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr393", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I5ZLL3-1" }, { "uniprot_canonical_ac": "A0A8I6A5M6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5M6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5M6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 650, "chemical_mass": 73411.0, "gene_names": "Arhgap25", "protein_name": "", "disease": [], "cellular_component": [ { "name": "phagocytic cup", "id": "GO:0001891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001891", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5M6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5M6" } ], "pmid": "" } ], "molecular_function": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5M6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5M6" } ], "pmid": "" } ], "biological_process": [ { "name": "phagocytosis, engulfment", "id": "GO:0006911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006911", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5M6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5M6" } ], "pmid": "" }, { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5M6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5M6" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5M6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5M6" } ], "pmid": "" }, { "name": "negative regulation of small GTPase mediated signal transduction", "id": "GO:0051058", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051058", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5M6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5M6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6A5M6-1" }, { "uniprot_canonical_ac": "A0A8I6AQ35-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQ35", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQ35" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 853, "chemical_mass": 98592.0, "gene_names": "Vps41;RGD1560511;Vps41", "protein_name": "Vacuolar protein sorting-associated protein 41 homolog", "disease": [ { "disease_id": "DOID:0070410", "name": "autosomal recessive spinocerebellar ataxia 29", "description": "An autosomal recessive cerebellar ataxia characterized by delayed motor development in early infancy followed by difficulty walking due to an ataxic gait or inability to walk, hypotonia, and variably impaired intellectual development that has_material_basis_in homozygous or compound heterozygous mutation in the VPS41 gene on chromosome 7p14.", "url": "https://disease-ontology.org/term/DOID:0070410", "evidence": [ { "id": "0070410", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070410" } ], "weight": 0.0 }, { "disease_id": "DOID:14330", "name": "Parkinson's disease", "description": "A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.", "url": "https://disease-ontology.org/term/DOID:14330", "evidence": [ { "id": "14330", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14330" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "HOPS complex", "id": "GO:0030897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030897", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQ35", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQ35" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQ35", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQ35" } ], "pmid": "" }, { "name": "Golgi-associated vesicle", "id": "GO:0005798", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005798", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQ35", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQ35" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQ35", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQ35" } ], "pmid": "" }, { "name": "late endosome membrane", "id": "GO:0031902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031902", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQ35", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQ35" } ], "pmid": "" }, { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQ35", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQ35" } ], "pmid": "" }, { "name": "clathrin-coated vesicle", "id": "GO:0030136", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030136", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQ35", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQ35" } ], "pmid": "" }, { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQ35", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQ35" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQ35", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQ35" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQ35", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQ35" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQ35", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQ35" } ], "pmid": "" }, { "name": "microtubule cytoskeleton", "id": "GO:0015630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015630", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQ35", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQ35" } ], "pmid": "" }, { "name": "late endosome", "id": "GO:0005770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005770", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQ35", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQ35" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQ35", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQ35" } ], "pmid": "" }, { "name": "vacuolar membrane", "id": "GO:0005774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005774", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQ35", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQ35" } ], "pmid": "" }, { "name": "AP-3 adaptor complex", "id": "GO:0030123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030123", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQ35", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQ35" } ], "pmid": "" }, { "name": "clathrin complex", "id": "GO:0071439", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071439", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQ35", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQ35" } ], "pmid": "" }, { "name": "lysosomal HOPS complex", "id": "GO:1902501", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902501", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQ35", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQ35" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQ35", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQ35" } ], "pmid": "" }, { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQ35", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQ35" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQ35", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQ35" } ], "pmid": "" }, { "name": "protein-membrane adaptor activity", "id": "GO:0043495", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043495", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQ35", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQ35" } ], "pmid": "" } ], "biological_process": [ { "name": "regulated exocytosis", "id": "GO:0045055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045055", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQ35", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQ35" } ], "pmid": "" }, { "name": "endosomal vesicle fusion", "id": "GO:0034058", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034058", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQ35", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQ35" } ], "pmid": "" }, { "name": "protein targeting to vacuole", "id": "GO:0006623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006623", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQ35", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQ35" } ], "pmid": "" }, { "name": "vacuolar transport", "id": "GO:0007034", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007034", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQ35", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQ35" } ], "pmid": "" }, { "name": "macroautophagy", "id": "GO:0016236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016236", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQ35", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQ35" } ], "pmid": "" }, { "name": "endosome to lysosome transport", "id": "GO:0008333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008333", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQ35", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQ35" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQ35", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQ35" } ], "pmid": "" }, { "name": "cellular response to starvation", "id": "GO:0009267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009267", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQ35", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQ35" } ], "pmid": "" }, { "name": "Golgi vesicle transport", "id": "GO:0048193", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048193", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQ35", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQ35" } ], "pmid": "" }, { "name": "late endosome to lysosome transport", "id": "GO:1902774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902774", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQ35", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQ35" } ], "pmid": "" }, { "name": "autophagosome-lysosome fusion", "id": "GO:0061909", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061909", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQ35", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQ35" } ], "pmid": "" }, { "name": "autophagy", "id": "GO:0006914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006914", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQ35", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQ35" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AQ35-1" }, { "uniprot_canonical_ac": "A0A0G2K899-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K899", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K899" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 214, "chemical_mass": 23825.0, "gene_names": "Acyp1", "protein_name": "acylphosphatase", "disease": [], "molecular_function": [ { "name": "acylphosphatase activity", "id": "GO:0003998", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003998", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K899", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K899" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A0G2K899-1" }, { "uniprot_canonical_ac": "A0A8I6A9M0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A9M0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A9M0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1004, "chemical_mass": 110332.0, "gene_names": "Eif4enif1;Eif4enif1;RGD1560908", "protein_name": "", "disease": [], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A9M0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A9M0" } ], "pmid": "" }, { "name": "kinase binding", "id": "GO:0019900", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019900", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A9M0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A9M0" } ], "pmid": "" }, { "name": "nuclear export signal receptor activity", "id": "GO:0005049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005049", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A9M0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A9M0" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A9M0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A9M0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A9M0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A9M0" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A9M0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A9M0" } ], "pmid": "" }, { "name": "P-body", "id": "GO:0000932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000932", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A9M0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A9M0" } ], "pmid": "" }, { "name": "cytoplasmic ribonucleoprotein granule", "id": "GO:0036464", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036464", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A9M0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A9M0" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of neuron differentiation", "id": "GO:0045665", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045665", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A9M0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A9M0" } ], "pmid": "" }, { "name": "mRNA stabilization", "id": "GO:0048255", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048255", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A9M0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A9M0" } ], "pmid": "" }, { "name": "negative regulation of translation", "id": "GO:0017148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017148", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A9M0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A9M0" } ], "pmid": "" }, { "name": "stem cell population maintenance", "id": "GO:0019827", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019827", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A9M0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A9M0" } ], "pmid": "" }, { "name": "miRNA-mediated gene silencing by inhibition of translation", "id": "GO:0035278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035278", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A9M0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A9M0" } ], "pmid": "" }, { "name": "positive regulation of nuclear-transcribed mRNA poly(A) tail shortening", "id": "GO:0060213", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060213", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A9M0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A9M0" } ], "pmid": "" }, { "name": "P-body assembly", "id": "GO:0033962", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033962", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A9M0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A9M0" } ], "pmid": "" }, { "name": "protein import into nucleus", "id": "GO:0006606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006606", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A9M0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A9M0" } ], "pmid": "" }, { "name": "negative regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA", "id": "GO:0106289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106289", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A9M0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A9M0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6A9M0-1", "start_pos": "246", "end_pos": "246", "site_lbl": "Thr246", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 246, "start_aa": "Thr", "end_pos": 246, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr246", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6A9M0-1" }, { "uniprot_canonical_ac": "A0A8I6A2Y4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2Y4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2Y4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 551, "chemical_mass": 65712.0, "gene_names": "Cfap45;Ccdc19;Cfap45", "protein_name": "Cilia- and flagella-associated protein 45", "disease": [ { "disease_id": "DOID:0051025", "name": "visceral heterotaxy 11", "description": "A visceral heterotaxy that is characterized by a failure to generate normal left-right visceral asymmetry during embryogenesis, which can result in heterotaxy syndrome or situs inversus totalis and that has_material_basis_in homozygous or compound heterozygous mutation in the CFAP45 gene on chromosome 1q23.", "url": "https://disease-ontology.org/term/DOID:0051025", "evidence": [ { "id": "0051025", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0051025" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "sperm end piece", "id": "GO:0097229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097229", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2Y4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2Y4" } ], "pmid": "" }, { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2Y4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2Y4" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2Y4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2Y4" } ], "pmid": "" }, { "name": "sperm flagellum", "id": "GO:0036126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036126", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2Y4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2Y4" } ], "pmid": "" }, { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2Y4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2Y4" } ], "pmid": "" }, { "name": "sperm principal piece", "id": "GO:0097228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097228", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2Y4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2Y4" } ], "pmid": "" }, { "name": "axonemal microtubule", "id": "GO:0005879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005879", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2Y4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2Y4" } ], "pmid": "" }, { "name": "sperm midpiece", "id": "GO:0097225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097225", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2Y4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2Y4" } ], "pmid": "" }, { "name": "9+2 motile cilium", "id": "GO:0097729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097729", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2Y4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2Y4" } ], "pmid": "" }, { "name": "9+0 motile cilium", "id": "GO:0097728", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097728", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2Y4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2Y4" } ], "pmid": "" }, { "name": "axonemal B tubule inner sheath", "id": "GO:0160112", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160112", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2Y4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2Y4" } ], "pmid": "" }, { "name": "motile cilium", "id": "GO:0031514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031514", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2Y4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2Y4" } ], "pmid": "" }, { "name": "polymeric cytoskeletal fiber", "id": "GO:0099513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099513", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2Y4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2Y4" } ], "pmid": "" } ], "molecular_function": [ { "name": "AMP binding", "id": "GO:0016208", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016208", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2Y4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2Y4" } ], "pmid": "" } ], "biological_process": [ { "name": "flagellated sperm motility", "id": "GO:0030317", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030317", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2Y4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2Y4" } ], "pmid": "" }, { "name": "regulation of cilium beat frequency involved in ciliary motility", "id": "GO:0060296", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060296", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2Y4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2Y4" } ], "pmid": "" }, { "name": "epithelial cilium movement involved in determination of left/right asymmetry", "id": "GO:0060287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060287", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2Y4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2Y4" } ], "pmid": "" }, { "name": "cerebrospinal fluid circulation", "id": "GO:0090660", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090660", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2Y4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2Y4" } ], "pmid": "" }, { "name": "establishment of left/right asymmetry", "id": "GO:0061966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061966", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2Y4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2Y4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6A2Y4-1" }, { "uniprot_canonical_ac": "A0A8I6A5T3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5T3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5T3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1452, "chemical_mass": 159951.0, "gene_names": "Kdm6a;Kdm6a;NEWGENE_1565481", "protein_name": "[histone H3]-trimethyl-L-lysine(27) demethylase", "disease": [ { "disease_id": "DOID:0060081", "name": "triple-receptor negative breast cancer", "description": "A breast cancer that is characterized by the absence of estrogen, progresterone and Her2 receptors.", "url": "https://disease-ontology.org/term/DOID:0060081", "evidence": [ { "id": "0060081", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060081" } ], "weight": 0.0 }, { "disease_id": "DOID:0060473", "name": "Kabuki syndrome", "description": "A syndrome characterized by multiple congenital anomalies and mental retardation. Other characteristics include a peculiar facial gestalt, short stature, skeletal and visceral abnormalities, cardiac anomalies, and immunological defects.", "url": "https://disease-ontology.org/term/DOID:0060473", "evidence": [ { "id": "0060473", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060473" } ], "weight": 0.0 }, { "disease_id": "DOID:0080188", "name": "chronic myelomonocytic leukemia", "description": "A chronic leukemia characterized by monocytosis, increased monocytes in the bone marrow, variable degrees of dysplasia, but an absence of immature granulocytes in the blood.", "url": "https://disease-ontology.org/term/DOID:0080188", "evidence": [ { "id": "0080188", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080188" } ], "weight": 0.0 }, { "disease_id": "DOID:0080202", "name": "adenoid cystic carcinoma", "description": "An adenocarcinoma that is characterized by bands or cylinders of hyalinized or mucinous stroma separating or surrounded by nests or cords of small epithelial cells.", "url": "https://disease-ontology.org/term/DOID:0080202", "evidence": [ { "id": "0080202", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080202" } ], "weight": 0.0 }, { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ], "weight": 0.0 }, { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:1996", "name": "rectum adenocarcinoma", "description": "A rectum cancer that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:1996", "evidence": [ { "id": "1996", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1996" } ], "weight": 0.0 }, { "disease_id": "DOID:234", "name": "colon adenocarcinoma", "description": "A colon carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:234", "evidence": [ { "id": "234", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:234" } ], "weight": 0.0 }, { "disease_id": "DOID:3748", "name": "esophagus squamous cell carcinoma", "description": "An esophageal carcinoma that derives_from epithelial squamous cells located_in the esophagus.", "url": "https://disease-ontology.org/term/DOID:3748", "evidence": [ { "id": "3748", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3748" } ], "weight": 0.0 }, { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 }, { "disease_id": "DOID:4006", "name": "bladder urothelial carcinoma", "description": "A bladder carcinoma that has_material_basis_in transitional cells located_in the lining of the bladder.", "url": "https://disease-ontology.org/term/DOID:4006", "evidence": [ { "id": "4006", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4006" } ], "weight": 0.0 }, { "disease_id": "DOID:4450", "name": "renal cell carcinoma", "description": "A renal carcinoma that has_material_basis_in the lining of the proximal convoluted renal tubule of the kidney.", "url": "https://disease-ontology.org/term/DOID:4450", "evidence": [ { "id": "4450", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4450" } ], "weight": 0.0 }, { "disease_id": "DOID:5409", "name": "lung small cell carcinoma", "description": "A lung carcinoma that has_material_basis_in primitive-appearing cells that are smaller than normal cells and is located_in the lung.", "url": "https://disease-ontology.org/term/DOID:5409", "evidence": [ { "id": "5409", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5409" } ], "weight": 0.0 }, { "disease_id": "DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia.", "url": "https://disease-ontology.org/term/DOID:5844", "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:7474", "name": "malignant pleural mesothelioma", "description": "A pleural cancer that has_material_basis_in mesothelium cells.", "url": "https://disease-ontology.org/term/DOID:7474", "evidence": [ { "id": "7474", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7474" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 }, { "disease_id": "DOID:9952", "name": "acute lymphoblastic leukemia", "description": "A acute leukemia that is characterized by over production of lymphoblasts.", "url": "https://disease-ontology.org/term/DOID:9952", "evidence": [ { "id": "9952", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9952" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5T3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5T3" } ], "pmid": "" }, { "name": "histone methyltransferase complex", "id": "GO:0035097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035097", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5T3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5T3" } ], "pmid": "" }, { "name": "MLL3/4 complex", "id": "GO:0044666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044666", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5T3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5T3" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5T3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5T3" } ], "pmid": "" }, { "name": "histone H3K27me2/H3K27me3 demethylase activity", "id": "GO:0071558", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071558", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5T3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5T3" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5T3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5T3" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5T3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5T3" } ], "pmid": "" }, { "name": "chromatin DNA binding", "id": "GO:0031490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031490", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5T3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5T3" } ], "pmid": "" } ], "biological_process": [ { "name": "heart morphogenesis", "id": "GO:0003007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003007", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5T3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5T3" } ], "pmid": "" }, { "name": "circulatory system development", "id": "GO:0072359", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072359", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5T3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5T3" } ], "pmid": "" }, { "name": "cellular response to angiotensin", "id": "GO:1904385", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904385", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5T3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5T3" } ], "pmid": "" }, { "name": "notochord morphogenesis", "id": "GO:0048570", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048570", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5T3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5T3" } ], "pmid": "" }, { "name": "cellular response to endothelin", "id": "GO:1990859", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990859", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5T3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5T3" } ], "pmid": "" }, { "name": "in utero embryonic development", "id": "GO:0001701", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001701", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5T3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5T3" } ], "pmid": "" }, { "name": "respiratory system process", "id": "GO:0003016", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003016", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5T3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5T3" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5T3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5T3" } ], "pmid": "" }, { "name": "heart development", "id": "GO:0007507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007507", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5T3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5T3" } ], "pmid": "" }, { "name": "positive regulation of gene expression", "id": "GO:0010628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010628", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5T3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5T3" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5T3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5T3" } ], "pmid": "" }, { "name": "response to hypoxia", "id": "GO:0001666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001666", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5T3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5T3" } ], "pmid": "" }, { "name": "multicellular organism growth", "id": "GO:0035264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035264", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5T3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5T3" } ], "pmid": "" }, { "name": "cellular response to hypoxia", "id": "GO:0071456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071456", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5T3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5T3" } ], "pmid": "" }, { "name": "neural tube closure", "id": "GO:0001843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001843", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5T3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5T3" } ], "pmid": "" }, { "name": "neural tube development", "id": "GO:0021915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021915", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5T3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5T3" } ], "pmid": "" }, { "name": "cellular response to transforming growth factor beta stimulus", "id": "GO:0071560", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071560", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5T3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5T3" } ], "pmid": "" }, { "name": "positive regulation of cell size", "id": "GO:0045793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045793", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5T3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5T3" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5T3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5T3" } ], "pmid": "" }, { "name": "embryonic organ development", "id": "GO:0048568", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048568", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5T3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5T3" } ], "pmid": "" }, { "name": "cellular response to vitamin D", "id": "GO:0071305", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071305", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5T3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5T3" } ], "pmid": "" }, { "name": "negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway", "id": "GO:1903298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903298", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5T3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5T3" } ], "pmid": "" }, { "name": "somite rostral/caudal axis specification", "id": "GO:0032525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032525", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5T3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5T3" } ], "pmid": "" }, { "name": "mesodermal cell differentiation", "id": "GO:0048333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048333", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5T3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5T3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6A5T3-1", "start_pos": "579", "end_pos": "579", "site_lbl": "Thr579", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 579, "start_aa": "Thr", "end_pos": 579, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr579", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I6A5T3-1", "start_pos": "991", "end_pos": "991", "site_lbl": "Thr991", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 991, "start_aa": "Thr", "end_pos": 991, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr991", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6A5T3-1" }, { "uniprot_canonical_ac": "A0A8I6A922-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A922", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A922" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 607, "chemical_mass": 65951.0, "gene_names": "Cables2", "protein_name": "", "disease": [], "biological_process": [ { "name": "in utero embryonic development", "id": "GO:0001701", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001701", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A922", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A922" } ], "pmid": "" }, { "name": "gastrulation", "id": "GO:0007369", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007369", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A922", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A922" } ], "pmid": "" }, { "name": "DNA damage response, signal transduction by p53 class mediator", "id": "GO:0030330", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030330", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A922", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A922" } ], "pmid": "" }, { "name": "gene expression", "id": "GO:0010467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010467", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A922", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A922" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A922", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A922" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6A922-1", "start_pos": "94", "end_pos": "94", "site_lbl": "Thr94", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 94, "start_aa": "Thr", "end_pos": 94, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr94", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6A922-1" }, { "uniprot_canonical_ac": "A0A8I6AQL7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQL7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQL7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 976, "chemical_mass": 106761.0, "gene_names": "Nek9;Nek9", "protein_name": "Serine/threonine-protein kinase Nek9", "disease": [ { "disease_id": "DOID:0060558", "name": "lethal congenital contracture syndrome", "description": "A syndrome characterized by congenital nonprogressive joint contractures. The contractures can involve the upper or lower limbs and/or the vertebral column, leading to various degrees of flexion or extension limitations evident at birth.", "url": "https://disease-ontology.org/term/DOID:0060558", "evidence": [ { "id": "0060558", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060558" } ], "weight": 0.0 }, { "disease_id": "DOID:0081378", "name": "amyotrophic lateral sclerosis type 24", "description": "An amyotrophic lateral sclerosis that is characterized by adult-onset loss of motor neurons and that has_material_basis_in heterozygous mutation in the NEK1 gene on chromosome 4q33.", "url": "https://disease-ontology.org/term/DOID:0081378", "evidence": [ { "id": "0081378", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081378" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQL7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQL7" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQL7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQL7" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQL7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQL7" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQL7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQL7" } ], "pmid": "" }, { "name": "protein kinase activator activity", "id": "GO:0030295", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030295", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQL7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQL7" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQL7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQL7" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQL7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQL7" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQL7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQL7" } ], "pmid": "" } ], "biological_process": [ { "name": "mitotic cell cycle", "id": "GO:0000278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000278", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQL7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQL7" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQL7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQL7" } ], "pmid": "" }, { "name": "regulation of mitotic cell cycle", "id": "GO:0007346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007346", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQL7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQL7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AQL7-1" }, { "uniprot_canonical_ac": "A0A8I5ZNS2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNS2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNS2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1317, "chemical_mass": 140296.0, "gene_names": "Atf7ip;Atf7ip", "protein_name": "", "disease": [ { "disease_id": "DOID:1059", "name": "intellectual disability", "description": "A specific developmental disorder that involves significant limitations both in mental functioning and in adaptive behavior such as communicating, taking care of him or herself, and social skills.", "url": "https://disease-ontology.org/term/DOID:1059", "evidence": [ { "id": "1059", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1059" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNS2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNS2" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNS2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNS2" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNS2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNS2" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNS2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNS2" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNS2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNS2" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNS2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNS2" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNS2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNS2" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNS2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNS2" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNS2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNS2" } ], "pmid": "" }, { "name": "DNA methylation-dependent constitutive heterochromatin formation", "id": "GO:0006346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006346", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNS2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNS2" } ], "pmid": "" } ], "molecular_function": [ { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNS2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNS2" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNS2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNS2" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZNS2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZNS2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I5ZNS2-1", "start_pos": "139", "end_pos": "139", "site_lbl": "Thr139", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 139, "start_aa": "Thr", "end_pos": 139, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr139", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I5ZNS2-1" }, { "uniprot_canonical_ac": "A0A8I6ABJ9-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABJ9" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 582, "chemical_mass": 62499.0, "gene_names": "Ythdf2", "protein_name": "YTH domain-containing family protein", "disease": [ { "disease_id": "DOID:0014667", "name": "disease of metabolism", "description": "A disease that involves errors in metabolic processes of building or degradation of molecules.", "url": "https://disease-ontology.org/term/DOID:0014667", "evidence": [ { "id": "0014667", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0014667" } ], "weight": 0.0 } ], "biological_process": [ { "name": "positive regulation of cap-independent translational initiation", "id": "GO:1903679", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903679", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABJ9" } ], "pmid": "" }, { "name": "regulation of rRNA processing", "id": "GO:2000232", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000232", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABJ9" } ], "pmid": "" }, { "name": "regulation of cell adhesion", "id": "GO:0030155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030155", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABJ9" } ], "pmid": "" }, { "name": "regulation of mRNA stability", "id": "GO:0043488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043488", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABJ9" } ], "pmid": "" }, { "name": "regulation of hematopoietic stem cell differentiation", "id": "GO:1902036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902036", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABJ9" } ], "pmid": "" }, { "name": "regulation of meiotic cell cycle process involved in oocyte maturation", "id": "GO:1903538", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903538", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABJ9" } ], "pmid": "" }, { "name": "oocyte maturation", "id": "GO:0001556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001556", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABJ9" } ], "pmid": "" }, { "name": "mRNA catabolic process", "id": "GO:0006402", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006402", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABJ9" } ], "pmid": "" }, { "name": "regulation of neurogenesis", "id": "GO:0050767", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050767", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABJ9" } ], "pmid": "" }, { "name": "hematopoietic stem cell proliferation", "id": "GO:0071425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071425", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABJ9" } ], "pmid": "" }, { "name": "stress granule assembly", "id": "GO:0034063", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034063", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABJ9" } ], "pmid": "" }, { "name": "mRNA destabilization", "id": "GO:0061157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061157", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABJ9" } ], "pmid": "" }, { "name": "spermatogonial cell division", "id": "GO:0007284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007284", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABJ9" } ], "pmid": "" }, { "name": "negative regulation of stem cell differentiation", "id": "GO:2000737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABJ9" } ], "pmid": "" }, { "name": "negative regulation of type I interferon-mediated signaling pathway", "id": "GO:0060339", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060339", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABJ9" } ], "pmid": "" }, { "name": "gamete generation", "id": "GO:0007276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007276", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABJ9" } ], "pmid": "" } ], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABJ9" } ], "pmid": "" }, { "name": "N6-methyladenosine-containing RNA reader activity", "id": "GO:1990247", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990247", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABJ9" } ], "pmid": "" }, { "name": "C5-methylcytidine-containing RNA reader activity", "id": "GO:0062153", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0062153", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABJ9" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABJ9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABJ9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABJ9" } ], "pmid": "" }, { "name": "P-body", "id": "GO:0000932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000932", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABJ9" } ], "pmid": "" }, { "name": "cytoplasmic ribonucleoprotein granule", "id": "GO:0036464", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036464", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABJ9" } ], "pmid": "" }, { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABJ9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6ABJ9-1", "start_pos": "381", "end_pos": "381", "site_lbl": "Thr381", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 381, "start_aa": "Thr", "end_pos": 381, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr381", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6ABJ9-1" }, { "uniprot_canonical_ac": "A0A8I6A9C9-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A9C9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A9C9" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 278, "chemical_mass": 29794.0, "gene_names": "Acrv1", "protein_name": "", "disease": [], "cellular_component": [ { "name": "acrosomal vesicle", "id": "GO:0001669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001669", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A9C9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A9C9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6A9C9-1" }, { "uniprot_canonical_ac": "A0A0G2K0X0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K0X0", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K0X0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 263, "chemical_mass": 30459.0, "gene_names": "Tafazzin;TAZ;Tafazzin;Taz", "protein_name": "Tafazzin family protein", "disease": [ { "disease_id": "DOID:0050476", "name": "Barth syndrome", "description": "A 3-methylglutaconic aciduria that has_material_basis_in X-linked inheritance of the tafazzin gene and is characterized by decreased production of an enzyme required to produce cardiolipin.", "url": "https://disease-ontology.org/term/DOID:0050476", "evidence": [ { "id": "0050476", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050476" } ], "weight": 0.0 }, { "disease_id": "DOID:0050545", "name": "visceral heterotaxy", "description": "A physical disorder characterized by the abnormal distribution of the major visceral organs within the chest and abdomen.", "url": "https://disease-ontology.org/term/DOID:0050545", "evidence": [ { "id": "0050545", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050545" } ], "weight": 0.0 }, { "disease_id": "DOID:0050700", "name": "cardiomyopathy", "description": "A heart disease and a myopathy that is characterized by deterioration of the function of the heart muscle.", "url": "https://disease-ontology.org/term/DOID:0050700", "evidence": [ { "id": "0050700", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050700" } ], "weight": 0.0 }, { "disease_id": "DOID:12930", "name": "dilated cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by an an enlarged heart and damage to the myocardium causing the heart to pump blood inefficiently.", "url": "https://disease-ontology.org/term/DOID:12930", "evidence": [ { "id": "12930", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12930" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K0X0", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K0X0" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K0X0", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K0X0" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K0X0", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K0X0" } ], "pmid": "" }, { "name": "mitochondrial intermembrane space", "id": "GO:0005758", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005758", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K0X0", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K0X0" } ], "pmid": "" }, { "name": "mitochondrial membrane", "id": "GO:0031966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031966", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K0X0", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K0X0" } ], "pmid": "" } ], "biological_process": [ { "name": "phospholipid metabolic process", "id": "GO:0006644", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006644", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K0X0", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K0X0" } ], "pmid": "" }, { "name": "positive regulation of ATP biosynthetic process", "id": "GO:2001171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001171", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K0X0", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K0X0" } ], "pmid": "" }, { "name": "positive regulation of cardiolipin metabolic process", "id": "GO:1900210", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900210", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K0X0", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K0X0" } ], "pmid": "" }, { "name": "cardiolipin acyl-chain remodeling", "id": "GO:0035965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035965", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K0X0", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K0X0" } ], "pmid": "" }, { "name": "cristae formation", "id": "GO:0042407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042407", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K0X0", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K0X0" } ], "pmid": "" }, { "name": "cardiolipin metabolic process", "id": "GO:0032048", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032048", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K0X0", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K0X0" } ], "pmid": "" }, { "name": "inner mitochondrial membrane organization", "id": "GO:0007007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007007", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K0X0", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K0X0" } ], "pmid": "" } ], "molecular_function": [ { "name": "acyltransferase activity", "id": "GO:0016746", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016746", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K0X0", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K0X0" } ], "pmid": "" }, { "name": "1-acylglycerophosphocholine O-acyltransferase activity", "id": "GO:0047184", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047184", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K0X0", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K0X0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A0G2K0X0-1" }, { "uniprot_canonical_ac": "A0A8I6APJ0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6APJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6APJ0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 141, "chemical_mass": 15822.0, "gene_names": "Lsm4;LSM4", "protein_name": "U6 snRNA-associated Sm-like protein LSm4", "disease": [ { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 }, { "disease_id": "DOID:1936", "name": "atherosclerosis", "description": "An arteriosclerotic cardiovascular disease that is characterized by the build-up of fatty material and calcium deposition in the arterial wall resulting in partial or complete occlusion of the arterial lumen. Disease is located within the tunica intima of large and small arteries.", "url": "https://disease-ontology.org/term/DOID:1936", "evidence": [ { "id": "1936", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1936" } ], "weight": 0.0 } ], "biological_process": [ { "name": "RNA processing", "id": "GO:0006396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006396", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6APJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6APJ0" } ], "pmid": "" }, { "name": "nuclear-transcribed mRNA catabolic process", "id": "GO:0000956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000956", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6APJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6APJ0" } ], "pmid": "" }, { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6APJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6APJ0" } ], "pmid": "" } ], "cellular_component": [ { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6APJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6APJ0" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6APJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6APJ0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6APJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6APJ0" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6APJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6APJ0" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6APJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6APJ0" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6APJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6APJ0" } ], "pmid": "" }, { "name": "precatalytic spliceosome", "id": "GO:0071011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071011", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6APJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6APJ0" } ], "pmid": "" }, { "name": "Lsm2-8 complex", "id": "GO:0120115", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120115", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6APJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6APJ0" } ], "pmid": "" }, { "name": "U4/U6 x U5 tri-snRNP complex", "id": "GO:0046540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046540", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6APJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6APJ0" } ], "pmid": "" }, { "name": "U2-type precatalytic spliceosome", "id": "GO:0071005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071005", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6APJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6APJ0" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6APJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6APJ0" } ], "pmid": "" }, { "name": "PH domain binding", "id": "GO:0042731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042731", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6APJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6APJ0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6APJ0-1" }, { "uniprot_canonical_ac": "A0A8I6AFQ6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AFQ6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AFQ6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 317, "chemical_mass": 35246.0, "gene_names": "Or52ae8;Olr115;Or52ae8;ratchr1-161443812-161442859_ORF", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AFQ6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AFQ6" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AFQ6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AFQ6" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AFQ6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AFQ6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AFQ6-1" }, { "uniprot_canonical_ac": "A0A8I6AI28-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AI28", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AI28" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 477, "chemical_mass": 54666.0, "gene_names": "Osbpl2", "protein_name": "Oxysterol-binding protein", "disease": [ { "disease_id": "DOID:0110588", "name": "autosomal dominant nonsyndromic deafness 67", "description": "An autosomal dominant nonsyndromic deafness that has_material_basis_in mutation in the OSBPL2 gene on chromosome 20q13.", "url": "https://disease-ontology.org/term/DOID:0110588", "evidence": [ { "id": "0110588", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110588" } ], "weight": 0.0 }, { "disease_id": "DOID:1824", "name": "status epilepticus", "description": "", "url": "https://disease-ontology.org/term/DOID:1824", "evidence": [ { "id": "1824", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1824" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AI28", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AI28" } ], "pmid": "" }, { "name": "presynaptic active zone cytoplasmic component", "id": "GO:0098831", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098831", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AI28", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AI28" } ], "pmid": "" }, { "name": "lipid droplet", "id": "GO:0005811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005811", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AI28", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AI28" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AI28", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AI28" } ], "pmid": "" }, { "name": "cytoplasmic side of plasma membrane", "id": "GO:0009898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009898", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AI28", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AI28" } ], "pmid": "" }, { "name": "stereocilium", "id": "GO:0032420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032420", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AI28", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AI28" } ], "pmid": "" } ], "molecular_function": [ { "name": "phosphatidylinositol-4,5-bisphosphate binding", "id": "GO:0005546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005546", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AI28", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AI28" } ], "pmid": "" }, { "name": "cholesterol binding", "id": "GO:0015485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015485", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AI28", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AI28" } ], "pmid": "" }, { "name": "phosphatidylinositol transfer activity", "id": "GO:0008526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008526", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AI28", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AI28" } ], "pmid": "" }, { "name": "cholesterol transfer activity", "id": "GO:0120020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120020", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AI28", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AI28" } ], "pmid": "" }, { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AI28", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AI28" } ], "pmid": "" } ], "biological_process": [ { "name": "plasma membrane organization", "id": "GO:0007009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007009", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AI28", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AI28" } ], "pmid": "" }, { "name": "protein homotetramerization", "id": "GO:0051289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051289", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AI28", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AI28" } ], "pmid": "" }, { "name": "phospholipid transport", "id": "GO:0015914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015914", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AI28", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AI28" } ], "pmid": "" }, { "name": "intracellular cholesterol transport", "id": "GO:0032367", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032367", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AI28", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AI28" } ], "pmid": "" }, { "name": "cholesterol transport", "id": "GO:0030301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030301", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AI28", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AI28" } ], "pmid": "" }, { "name": "regulation of presynaptic cytosolic calcium ion concentration", "id": "GO:0099509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099509", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AI28", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AI28" } ], "pmid": "" }, { "name": "regulation of synaptic vesicle priming", "id": "GO:0010807", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010807", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AI28", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AI28" } ], "pmid": "" }, { "name": "lipid transport", "id": "GO:0006869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006869", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AI28", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AI28" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AI28-1" }, { "uniprot_canonical_ac": "A0A8I6AI41-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AI41", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AI41" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 106, "chemical_mass": 11561.0, "gene_names": "ENSRNOG00000066406", "protein_name": "Ig-like domain-containing protein", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AI41", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AI41" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AI41", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AI41" } ], "pmid": "" }, { "name": "immunoglobulin complex", "id": "GO:0019814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019814", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AI41", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AI41" } ], "pmid": "" } ], "biological_process": [ { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AI41", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AI41" } ], "pmid": "" }, { "name": "adaptive immune response", "id": "GO:0002250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002250", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AI41", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AI41" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6AI41-1", "start_pos": "14", "end_pos": "14", "site_lbl": "Thr14", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 14, "start_aa": "Thr", "end_pos": 14, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr14", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6AI41-1" }, { "uniprot_canonical_ac": "A0A8I6AKS7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AKS7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AKS7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 294, "chemical_mass": 33455.0, "gene_names": "Teddm3;RGD1560559;Teddm3", "protein_name": "", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AKS7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AKS7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AKS7-1" }, { "uniprot_canonical_ac": "A0A8I6AV54-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AV54", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AV54" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 257, "chemical_mass": 28534.0, "gene_names": "Dmrtc1b;AABR07039316.1;Dmrtc1b", "protein_name": "", "disease": [], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AV54", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AV54" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AV54-1" }, { "uniprot_canonical_ac": "A0A8I6GGA1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GGA1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GGA1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 156, "chemical_mass": 17753.0, "gene_names": "ENSRNOG00000067114", "protein_name": "Large ribosomal subunit protein uL23", "disease": [], "cellular_component": [ { "name": "ribosomal subunit", "id": "GO:0044391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044391", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GGA1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GGA1" } ], "pmid": "" }, { "name": "cytosolic ribosome", "id": "GO:0022626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022626", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GGA1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GGA1" } ], "pmid": "" } ], "biological_process": [ { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GGA1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GGA1" } ], "pmid": "" } ], "molecular_function": [ { "name": "rRNA binding", "id": "GO:0019843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019843", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GGA1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GGA1" } ], "pmid": "" }, { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GGA1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GGA1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6GGA1-1" }, { "uniprot_canonical_ac": "A0A8J8XFA0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8J8XFA0", "url": "https://www.uniprot.org/uniprotkb/A0A8J8XFA0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 663, "chemical_mass": 73786.0, "gene_names": "Rapgefl1;Rapgefl1", "protein_name": "", "disease": [], "biological_process": [ { "name": "Rap protein signal transduction", "id": "GO:0032486", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032486", "evidence": [ { "database": "UniProtKB", "id": "A0A8J8XFA0", "url": "https://www.uniprot.org/uniprotkb/A0A8J8XFA0" } ], "pmid": "" }, { "name": "positive regulation of protein secretion", "id": "GO:0050714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050714", "evidence": [ { "database": "UniProtKB", "id": "A0A8J8XFA0", "url": "https://www.uniprot.org/uniprotkb/A0A8J8XFA0" } ], "pmid": "" }, { "name": "positive regulation of smooth muscle cell migration", "id": "GO:0014911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014911", "evidence": [ { "database": "UniProtKB", "id": "A0A8J8XFA0", "url": "https://www.uniprot.org/uniprotkb/A0A8J8XFA0" } ], "pmid": "" }, { "name": "ganglion development", "id": "GO:0061548", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061548", "evidence": [ { "database": "UniProtKB", "id": "A0A8J8XFA0", "url": "https://www.uniprot.org/uniprotkb/A0A8J8XFA0" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8J8XFA0", "url": "https://www.uniprot.org/uniprotkb/A0A8J8XFA0" } ], "pmid": "" } ], "molecular_function": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8J8XFA0", "url": "https://www.uniprot.org/uniprotkb/A0A8J8XFA0" } ], "pmid": "" }, { "name": "cAMP binding", "id": "GO:0030552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030552", "evidence": [ { "database": "UniProtKB", "id": "A0A8J8XFA0", "url": "https://www.uniprot.org/uniprotkb/A0A8J8XFA0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8J8XFA0-1", "start_pos": "47", "end_pos": "47", "site_lbl": "Thr47", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 47, "start_aa": "Thr", "end_pos": 47, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr47", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8J8XFA0-1" }, { "uniprot_canonical_ac": "A0A8J8YAJ6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8J8YAJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8J8YAJ6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 89, "chemical_mass": 10060.0, "gene_names": "Defb28", "protein_name": "Beta-defensin", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8J8YAJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8J8YAJ6" } ], "pmid": "" } ], "biological_process": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A0A8J8YAJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8J8YAJ6" } ], "pmid": "" }, { "name": "defense response to bacterium", "id": "GO:0042742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042742", "evidence": [ { "database": "UniProtKB", "id": "A0A8J8YAJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8J8YAJ6" } ], "pmid": "" }, { "name": "killing of cells of another organism", "id": "GO:0031640", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031640", "evidence": [ { "database": "UniProtKB", "id": "A0A8J8YAJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8J8YAJ6" } ], "pmid": "" } ], "molecular_function": [ { "name": "membrane destabilizing activity", "id": "GO:0140912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140912", "evidence": [ { "database": "UniProtKB", "id": "A0A8J8YAJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8J8YAJ6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8J8YAJ6-1" }, { "uniprot_canonical_ac": "F7F0R0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F7F0R0", "url": "https://www.uniprot.org/uniprotkb/F7F0R0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 359, "chemical_mass": 40112.0, "gene_names": "Tmod3", "protein_name": "", "disease": [], "molecular_function": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "F7F0R0", "url": "https://www.uniprot.org/uniprotkb/F7F0R0" } ], "pmid": "" }, { "name": "tropomyosin binding", "id": "GO:0005523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005523", "evidence": [ { "database": "UniProtKB", "id": "F7F0R0", "url": "https://www.uniprot.org/uniprotkb/F7F0R0" } ], "pmid": "" } ], "biological_process": [ { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "F7F0R0", "url": "https://www.uniprot.org/uniprotkb/F7F0R0" } ], "pmid": "" }, { "name": "erythrocyte development", "id": "GO:0048821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048821", "evidence": [ { "database": "UniProtKB", "id": "F7F0R0", "url": "https://www.uniprot.org/uniprotkb/F7F0R0" } ], "pmid": "" }, { "name": "pointed-end actin filament capping", "id": "GO:0051694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051694", "evidence": [ { "database": "UniProtKB", "id": "F7F0R0", "url": "https://www.uniprot.org/uniprotkb/F7F0R0" } ], "pmid": "" }, { "name": "positive regulation of mitotic cell cycle phase transition", "id": "GO:1901992", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901992", "evidence": [ { "database": "UniProtKB", "id": "F7F0R0", "url": "https://www.uniprot.org/uniprotkb/F7F0R0" } ], "pmid": "" } ], "cellular_component": [ { "name": "striated muscle thin filament", "id": "GO:0005865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005865", "evidence": [ { "database": "UniProtKB", "id": "F7F0R0", "url": "https://www.uniprot.org/uniprotkb/F7F0R0" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "F7F0R0", "url": "https://www.uniprot.org/uniprotkb/F7F0R0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F7F0R0-1" }, { "uniprot_canonical_ac": "F7F115-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F7F115", "url": "https://www.uniprot.org/uniprotkb/F7F115" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 405, "chemical_mass": 46997.0, "gene_names": "Upf3a", "protein_name": "", "disease": [], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "F7F115", "url": "https://www.uniprot.org/uniprotkb/F7F115" } ], "pmid": "" }, { "name": "telomeric DNA binding", "id": "GO:0042162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042162", "evidence": [ { "database": "UniProtKB", "id": "F7F115", "url": "https://www.uniprot.org/uniprotkb/F7F115" } ], "pmid": "" }, { "name": "protein sequestering activity", "id": "GO:0140311", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140311", "evidence": [ { "database": "UniProtKB", "id": "F7F115", "url": "https://www.uniprot.org/uniprotkb/F7F115" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F7F115", "url": "https://www.uniprot.org/uniprotkb/F7F115" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "F7F115", "url": "https://www.uniprot.org/uniprotkb/F7F115" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F7F115", "url": "https://www.uniprot.org/uniprotkb/F7F115" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "F7F115", "url": "https://www.uniprot.org/uniprotkb/F7F115" } ], "pmid": "" }, { "name": "exon-exon junction complex", "id": "GO:0035145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035145", "evidence": [ { "database": "UniProtKB", "id": "F7F115", "url": "https://www.uniprot.org/uniprotkb/F7F115" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of translation", "id": "GO:0045727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045727", "evidence": [ { "database": "UniProtKB", "id": "F7F115", "url": "https://www.uniprot.org/uniprotkb/F7F115" } ], "pmid": "" }, { "name": "negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay", "id": "GO:2000623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000623", "evidence": [ { "database": "UniProtKB", "id": "F7F115", "url": "https://www.uniprot.org/uniprotkb/F7F115" } ], "pmid": "" }, { "name": "positive regulation of mRNA cis splicing, via spliceosome", "id": "GO:1905746", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905746", "evidence": [ { "database": "UniProtKB", "id": "F7F115", "url": "https://www.uniprot.org/uniprotkb/F7F115" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F7F115-1" }, { "uniprot_canonical_ac": "F7F3K1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F7F3K1", "url": "https://www.uniprot.org/uniprotkb/F7F3K1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 737, "chemical_mass": 79057.0, "gene_names": "Lrp10", "protein_name": "Low-density lipoprotein receptor-related protein 10", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F7F3K1", "url": "https://www.uniprot.org/uniprotkb/F7F3K1" } ], "pmid": "" }, { "name": "clathrin-coated pit", "id": "GO:0005905", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005905", "evidence": [ { "database": "UniProtKB", "id": "F7F3K1", "url": "https://www.uniprot.org/uniprotkb/F7F3K1" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F7F3K1", "url": "https://www.uniprot.org/uniprotkb/F7F3K1" } ], "pmid": "" } ], "biological_process": [ { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "F7F3K1", "url": "https://www.uniprot.org/uniprotkb/F7F3K1" } ], "pmid": "" }, { "name": "lipid transport", "id": "GO:0006869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006869", "evidence": [ { "database": "UniProtKB", "id": "F7F3K1", "url": "https://www.uniprot.org/uniprotkb/F7F3K1" } ], "pmid": "" }, { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "F7F3K1", "url": "https://www.uniprot.org/uniprotkb/F7F3K1" } ], "pmid": "" }, { "name": "inner ear development", "id": "GO:0048839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048839", "evidence": [ { "database": "UniProtKB", "id": "F7F3K1", "url": "https://www.uniprot.org/uniprotkb/F7F3K1" } ], "pmid": "" } ], "molecular_function": [ { "name": "low-density lipoprotein particle receptor activity", "id": "GO:0005041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005041", "evidence": [ { "database": "UniProtKB", "id": "F7F3K1", "url": "https://www.uniprot.org/uniprotkb/F7F3K1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "F7F3K1-1", "start_pos": "214", "end_pos": "214", "site_lbl": "Thr214", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 214, "start_aa": "Thr", "end_pos": 214, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr214", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "F7F3K1-1", "start_pos": "393", "end_pos": "393", "site_lbl": "Thr393", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 393, "start_aa": "Thr", "end_pos": 393, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr393", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "F7F3K1-1", "start_pos": "608", "end_pos": "608", "site_lbl": "Thr608", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 608, "start_aa": "Thr", "end_pos": 608, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr608", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "F7F3K1-1", "start_pos": "648", "end_pos": "648", "site_lbl": "Thr648", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 648, "start_aa": "Thr", "end_pos": 648, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr648", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "F7F3K1-1", "start_pos": "696", "end_pos": "696", "site_lbl": "Thr696", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 696, "start_aa": "Thr", "end_pos": 696, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr696", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "F7F3K1-1" }, { "uniprot_canonical_ac": "F7FHZ1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F7FHZ1", "url": "https://www.uniprot.org/uniprotkb/F7FHZ1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 473, "chemical_mass": 51679.0, "gene_names": "Ifngr1;Ifngr1;Ifngr", "protein_name": "Interferon gamma receptor 1", "disease": [ { "disease_id": "DOID:0111955", "name": "immunodeficiency 27A", "description": "A primary immunodeficiency disease characterized by high circulating levels of IFNG, failure of cellular responses to IFNG, and early and often fatal mycobacterial infections that has_material_basis_in homozygous or compound heterozygous mutation in the IFNGR1 gene on chromosome 6q23.3.", "url": "https://disease-ontology.org/term/DOID:0111955", "evidence": [ { "id": "0111955", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111955" } ], "weight": 0.0 }, { "disease_id": "DOID:0111956", "name": "immunodeficiency 27B", "description": "A primary immunodeficiency disease characterized by residual cellular responses to IFNG in vitro and recurrent, moderately severe infections with environmental mycobacteria or bacillus Calmette-Guerin that has_material_basis_in heterozygous mutation in the IFNGR1 gene on chromosome 6q23.3.", "url": "https://disease-ontology.org/term/DOID:0111956", "evidence": [ { "id": "0111956", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111956" } ], "weight": 0.0 }, { "disease_id": "DOID:11476", "name": "osteoporosis", "description": "A bone resorption disease characterized by decreased density of normally mineralized bone which results_in the thinning of bone tissue and decreased mechanical strength.", "url": "https://disease-ontology.org/term/DOID:11476", "evidence": [ { "id": "11476", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11476" } ], "weight": 0.0 }, { "disease_id": "DOID:1205", "name": "allergic disease", "description": "An immune system disease that is an exaggerated immune response to allergens, such as insect venom, dust mites, pollen, pet dander, drugs or some foods.", "url": "https://disease-ontology.org/term/DOID:1205", "evidence": [ { "id": "1205", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1205" } ], "weight": 0.0 }, { "disease_id": "DOID:13141", "name": "uveitis", "description": "An uveal disease is characterized by inflammation of any of the layers of the uvea of the eye, which includes the iris, ciliary body, and choroid.", "url": "https://disease-ontology.org/term/DOID:13141", "evidence": [ { "id": "13141", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13141" } ], "weight": 0.0 }, { "disease_id": "DOID:2043", "name": "hepatitis B", "description": "A viral hepatitis that results_in inflammation located_in liver, has_material_basis_in Hepatitis B virus (Orthohepadnavirus hominoidei), which is transmitted_by sexual contact, blood transfusions, or fomites like needles or syringes. The infection has_symptom fever, fatigue, loss of appetite, nausea, vomiting, abdominal pain, clay-colored bowel movements, joint pain, and jaundice.", "url": "https://disease-ontology.org/term/DOID:2043", "evidence": [ { "id": "2043", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2043" } ], "weight": 0.0 }, { "disease_id": "DOID:2349", "name": "arteriosclerosis", "description": "An artery disease that is characterized by a thickening and hardening of arterial walls in the arteries.", "url": "https://disease-ontology.org/term/DOID:2349", "evidence": [ { "id": "2349", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2349" } ], "weight": 0.0 }, { "disease_id": "DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.", "url": "https://disease-ontology.org/term/DOID:2841", "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ], "weight": 0.0 }, { "disease_id": "DOID:2957", "name": "pulmonary tuberculosis", "description": "A tuberculosis that is a contagious disease located_in lungs. The infection has_symptom fever, has_symptom cough, has_symptom difficulty in breathing, has_symptom inflammatory infiltrations, has_symptom formation of tubercles, has_symptom caseation, has_symptom pleural effusion, and has_symptom fibrosis.", "url": "https://disease-ontology.org/term/DOID:2957", "evidence": [ { "id": "2957", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2957" } ], "weight": 0.0 }, { "disease_id": "DOID:399", "name": "tuberculosis", "description": "A primary bacterial infectious disease that is located_in lungs, located_in lymph nodes, located_in pericardium, located_in brain, located_in pleura or located_in gastrointestinal tract, has_material_basis_in Mycobacterium tuberculosis, which is transmitted_by droplets released into the air when an infected person coughs or sneezes.", "url": "https://disease-ontology.org/term/DOID:399", "evidence": [ { "id": "399", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:399" } ], "weight": 0.0 }, { "disease_id": "DOID:6432", "name": "pulmonary hypertension", "description": "A hypertension characterized by an increase of blood pressure in the pulmonary artery, pulmonary vein or pulmonary capillaries.", "url": "https://disease-ontology.org/term/DOID:6432", "evidence": [ { "id": "6432", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6432" } ], "weight": 0.0 }, { "disease_id": "DOID:824", "name": "periodontitis", "description": "", "url": "https://disease-ontology.org/term/DOID:824", "evidence": [ { "id": "824", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:824" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "type II interferon receptor activity", "id": "GO:0004906", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004906", "evidence": [ { "database": "UniProtKB", "id": "F7FHZ1", "url": "https://www.uniprot.org/uniprotkb/F7FHZ1" } ], "pmid": "" }, { "name": "cytokine binding", "id": "GO:0019955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019955", "evidence": [ { "database": "UniProtKB", "id": "F7FHZ1", "url": "https://www.uniprot.org/uniprotkb/F7FHZ1" } ], "pmid": "" }, { "name": "cytokine receptor activity", "id": "GO:0004896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004896", "evidence": [ { "database": "UniProtKB", "id": "F7FHZ1", "url": "https://www.uniprot.org/uniprotkb/F7FHZ1" } ], "pmid": "" } ], "biological_process": [ { "name": "microglial cell activation", "id": "GO:0001774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001774", "evidence": [ { "database": "UniProtKB", "id": "F7FHZ1", "url": "https://www.uniprot.org/uniprotkb/F7FHZ1" } ], "pmid": "" }, { "name": "positive regulation of gene expression", "id": "GO:0010628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010628", "evidence": [ { "database": "UniProtKB", "id": "F7FHZ1", "url": "https://www.uniprot.org/uniprotkb/F7FHZ1" } ], "pmid": "" }, { "name": "astrocyte activation", "id": "GO:0048143", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048143", "evidence": [ { "database": "UniProtKB", "id": "F7FHZ1", "url": "https://www.uniprot.org/uniprotkb/F7FHZ1" } ], "pmid": "" }, { "name": "defense response to virus", "id": "GO:0051607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051607", "evidence": [ { "database": "UniProtKB", "id": "F7FHZ1", "url": "https://www.uniprot.org/uniprotkb/F7FHZ1" } ], "pmid": "" }, { "name": "positive regulation of amyloid-beta formation", "id": "GO:1902004", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902004", "evidence": [ { "database": "UniProtKB", "id": "F7FHZ1", "url": "https://www.uniprot.org/uniprotkb/F7FHZ1" } ], "pmid": "" }, { "name": "type II interferon-mediated signaling pathway", "id": "GO:0060333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060333", "evidence": [ { "database": "UniProtKB", "id": "F7FHZ1", "url": "https://www.uniprot.org/uniprotkb/F7FHZ1" } ], "pmid": "" }, { "name": "positive regulation of tumor necrosis factor production", "id": "GO:0032760", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032760", "evidence": [ { "database": "UniProtKB", "id": "F7FHZ1", "url": "https://www.uniprot.org/uniprotkb/F7FHZ1" } ], "pmid": "" }, { "name": "negative regulation of amyloid-beta clearance", "id": "GO:1900222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900222", "evidence": [ { "database": "UniProtKB", "id": "F7FHZ1", "url": "https://www.uniprot.org/uniprotkb/F7FHZ1" } ], "pmid": "" }, { "name": "cytokine-mediated signaling pathway", "id": "GO:0019221", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019221", "evidence": [ { "database": "UniProtKB", "id": "F7FHZ1", "url": "https://www.uniprot.org/uniprotkb/F7FHZ1" } ], "pmid": "" }, { "name": "type III interferon-mediated signaling pathway", "id": "GO:0038196", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038196", "evidence": [ { "database": "UniProtKB", "id": "F7FHZ1", "url": "https://www.uniprot.org/uniprotkb/F7FHZ1" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F7FHZ1", "url": "https://www.uniprot.org/uniprotkb/F7FHZ1" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F7FHZ1", "url": "https://www.uniprot.org/uniprotkb/F7FHZ1" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "F7FHZ1", "url": "https://www.uniprot.org/uniprotkb/F7FHZ1" } ], "pmid": "" }, { "name": "vesicle", "id": "GO:0031982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031982", "evidence": [ { "database": "UniProtKB", "id": "F7FHZ1", "url": "https://www.uniprot.org/uniprotkb/F7FHZ1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "F7FHZ1-1", "start_pos": "430", "end_pos": "430", "site_lbl": "Thr430", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 430, "start_aa": "Thr", "end_pos": 430, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr430", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "F7FHZ1-1" }, { "uniprot_canonical_ac": "F7FQA4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F7FQA4", "url": "https://www.uniprot.org/uniprotkb/F7FQA4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 819, "chemical_mass": 89512.0, "gene_names": "Zbtb17;Zbtb17;Zfp100", "protein_name": "Zinc finger and BTB domain-containing protein 17", "disease": [], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "F7FQA4", "url": "https://www.uniprot.org/uniprotkb/F7FQA4" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F7FQA4", "url": "https://www.uniprot.org/uniprotkb/F7FQA4" } ], "pmid": "" }, { "name": "negative regulation of cell population proliferation", "id": "GO:0008285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008285", "evidence": [ { "database": "UniProtKB", "id": "F7FQA4", "url": "https://www.uniprot.org/uniprotkb/F7FQA4" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "F7FQA4", "url": "https://www.uniprot.org/uniprotkb/F7FQA4" } ], "pmid": "" }, { "name": "regulation of immune system process", "id": "GO:0002682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002682", "evidence": [ { "database": "UniProtKB", "id": "F7FQA4", "url": "https://www.uniprot.org/uniprotkb/F7FQA4" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "F7FQA4", "url": "https://www.uniprot.org/uniprotkb/F7FQA4" } ], "pmid": "" }, { "name": "regulation of cytokine production", "id": "GO:0001817", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001817", "evidence": [ { "database": "UniProtKB", "id": "F7FQA4", "url": "https://www.uniprot.org/uniprotkb/F7FQA4" } ], "pmid": "" }, { "name": "gastrulation with mouth forming second", "id": "GO:0001702", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001702", "evidence": [ { "database": "UniProtKB", "id": "F7FQA4", "url": "https://www.uniprot.org/uniprotkb/F7FQA4" } ], "pmid": "" }, { "name": "ectoderm development", "id": "GO:0007398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007398", "evidence": [ { "database": "UniProtKB", "id": "F7FQA4", "url": "https://www.uniprot.org/uniprotkb/F7FQA4" } ], "pmid": "" }, { "name": "G1 to G0 transition", "id": "GO:0070314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070314", "evidence": [ { "database": "UniProtKB", "id": "F7FQA4", "url": "https://www.uniprot.org/uniprotkb/F7FQA4" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "F7FQA4", "url": "https://www.uniprot.org/uniprotkb/F7FQA4" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "F7FQA4", "url": "https://www.uniprot.org/uniprotkb/F7FQA4" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F7FQA4", "url": "https://www.uniprot.org/uniprotkb/F7FQA4" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "F7FQA4", "url": "https://www.uniprot.org/uniprotkb/F7FQA4" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "F7FQA4", "url": "https://www.uniprot.org/uniprotkb/F7FQA4" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "F7FQA4", "url": "https://www.uniprot.org/uniprotkb/F7FQA4" } ], "pmid": "" }, { "name": "transcription coactivator binding", "id": "GO:0001223", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001223", "evidence": [ { "database": "UniProtKB", "id": "F7FQA4", "url": "https://www.uniprot.org/uniprotkb/F7FQA4" } ], "pmid": "" }, { "name": "core promoter sequence-specific DNA binding", "id": "GO:0001046", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001046", "evidence": [ { "database": "UniProtKB", "id": "F7FQA4", "url": "https://www.uniprot.org/uniprotkb/F7FQA4" } ], "pmid": "" }, { "name": "DNA-binding transcription factor binding", "id": "GO:0140297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140297", "evidence": [ { "database": "UniProtKB", "id": "F7FQA4", "url": "https://www.uniprot.org/uniprotkb/F7FQA4" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F7FQA4", "url": "https://www.uniprot.org/uniprotkb/F7FQA4" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F7FQA4", "url": "https://www.uniprot.org/uniprotkb/F7FQA4" } ], "pmid": "" }, { "name": "protein-DNA complex", "id": "GO:0032993", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032993", "evidence": [ { "database": "UniProtKB", "id": "F7FQA4", "url": "https://www.uniprot.org/uniprotkb/F7FQA4" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "F7FQA4", "url": "https://www.uniprot.org/uniprotkb/F7FQA4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F7FQA4-1" }, { "uniprot_canonical_ac": "C0HLN0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "C0HLN0", "url": "https://www.uniprot.org/uniprotkb/C0HLN0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 54, "chemical_mass": 6358.0, "gene_names": "Pigbos1;Pigbos1", "protein_name": "Protein PIGBOS1", "disease": [], "cellular_component": [ { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "C0HLN0", "url": "https://www.uniprot.org/uniprotkb/C0HLN0" } ], "pmid": "" } ], "biological_process": [ { "name": "response to unfolded protein", "id": "GO:0006986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006986", "evidence": [ { "database": "UniProtKB", "id": "C0HLN0", "url": "https://www.uniprot.org/uniprotkb/C0HLN0" } ], "pmid": "" }, { "name": "regulation of endoplasmic reticulum unfolded protein response", "id": "GO:1900101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900101", "evidence": [ { "database": "UniProtKB", "id": "C0HLN0", "url": "https://www.uniprot.org/uniprotkb/C0HLN0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "C0HLN0-1" }, { "uniprot_canonical_ac": "A6HK25-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A6HK25", "url": "https://www.uniprot.org/uniprotkb/A6HK25" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 548, "chemical_mass": 60480.0, "gene_names": "Tcam1;Tcam1p;Tcam1", "protein_name": "Intercellular adhesion molecule 1", "disease": [ { "disease_id": "DOID:12930", "name": "dilated cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by an an enlarged heart and damage to the myocardium causing the heart to pump blood inefficiently.", "url": "https://disease-ontology.org/term/DOID:12930", "evidence": [ { "id": "12930", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12930" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "integrin binding", "id": "GO:0005178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005178", "evidence": [ { "database": "UniProtKB", "id": "A6HK25", "url": "https://www.uniprot.org/uniprotkb/A6HK25" } ], "pmid": "" } ], "biological_process": [ { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "A6HK25", "url": "https://www.uniprot.org/uniprotkb/A6HK25" } ], "pmid": "" }, { "name": "cellular response to glucose stimulus", "id": "GO:0071333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071333", "evidence": [ { "database": "UniProtKB", "id": "A6HK25", "url": "https://www.uniprot.org/uniprotkb/A6HK25" } ], "pmid": "" }, { "name": "leukocyte cell-cell adhesion", "id": "GO:0007159", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007159", "evidence": [ { "database": "UniProtKB", "id": "A6HK25", "url": "https://www.uniprot.org/uniprotkb/A6HK25" } ], "pmid": "" }, { "name": "leukocyte migration", "id": "GO:0050900", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050900", "evidence": [ { "database": "UniProtKB", "id": "A6HK25", "url": "https://www.uniprot.org/uniprotkb/A6HK25" } ], "pmid": "" }, { "name": "immune effector process", "id": "GO:0002252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002252", "evidence": [ { "database": "UniProtKB", "id": "A6HK25", "url": "https://www.uniprot.org/uniprotkb/A6HK25" } ], "pmid": "" } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A6HK25", "url": "https://www.uniprot.org/uniprotkb/A6HK25" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A6HK25-1" }, { "uniprot_canonical_ac": "A6HMU0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A6HMU0", "url": "https://www.uniprot.org/uniprotkb/A6HMU0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 315, "chemical_mass": 35556.0, "gene_names": "Or5ak25;Olr442;Or5ak25;TB 567;ratchr3-68554730-68553783_ORF", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A6HMU0", "url": "https://www.uniprot.org/uniprotkb/A6HMU0" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A6HMU0", "url": "https://www.uniprot.org/uniprotkb/A6HMU0" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A6HMU0", "url": "https://www.uniprot.org/uniprotkb/A6HMU0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A6HMU0-1" }, { "uniprot_canonical_ac": "A6JUI2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A6JUI2", "url": "https://www.uniprot.org/uniprotkb/A6JUI2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 311, "chemical_mass": 34622.0, "gene_names": "Or1n1b;Olr416;Or1n1b;TB 334", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A6JUI2", "url": "https://www.uniprot.org/uniprotkb/A6JUI2" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A6JUI2", "url": "https://www.uniprot.org/uniprotkb/A6JUI2" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A6JUI2", "url": "https://www.uniprot.org/uniprotkb/A6JUI2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A6JUI2-1" }, { "uniprot_canonical_ac": "A6KT88-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A6KT88", "url": "https://www.uniprot.org/uniprotkb/A6KT88" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 160, "chemical_mass": 17605.0, "gene_names": "Ier3;Dif2;Ier3;Iex1;Ler3;Prg1", "protein_name": "", "disease": [ { "disease_id": "DOID:0081312", "name": "T-cell non-Hodgkin lymphoma", "description": "A non-Hodgkin lymphoma of T-cell lineage.", "url": "https://disease-ontology.org/term/DOID:0081312", "evidence": [ { "id": "0081312", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081312" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A6KT88", "url": "https://www.uniprot.org/uniprotkb/A6KT88" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A6KT88", "url": "https://www.uniprot.org/uniprotkb/A6KT88" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of nucleocytoplasmic transport", "id": "GO:0046822", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046822", "evidence": [ { "database": "UniProtKB", "id": "A6KT88", "url": "https://www.uniprot.org/uniprotkb/A6KT88" } ], "pmid": "" }, { "name": "negative regulation of inflammatory response", "id": "GO:0050728", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050728", "evidence": [ { "database": "UniProtKB", "id": "A6KT88", "url": "https://www.uniprot.org/uniprotkb/A6KT88" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "A6KT88", "url": "https://www.uniprot.org/uniprotkb/A6KT88" } ], "pmid": "" }, { "name": "intrinsic apoptotic signaling pathway in response to DNA damage", "id": "GO:0008630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008630", "evidence": [ { "database": "UniProtKB", "id": "A6KT88", "url": "https://www.uniprot.org/uniprotkb/A6KT88" } ], "pmid": "" }, { "name": "negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "id": "GO:1901029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901029", "evidence": [ { "database": "UniProtKB", "id": "A6KT88", "url": "https://www.uniprot.org/uniprotkb/A6KT88" } ], "pmid": "" }, { "name": "negative regulation of glycolytic process", "id": "GO:0045820", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045820", "evidence": [ { "database": "UniProtKB", "id": "A6KT88", "url": "https://www.uniprot.org/uniprotkb/A6KT88" } ], "pmid": "" }, { "name": "negative regulation of systemic arterial blood pressure", "id": "GO:0003085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003085", "evidence": [ { "database": "UniProtKB", "id": "A6KT88", "url": "https://www.uniprot.org/uniprotkb/A6KT88" } ], "pmid": "" }, { "name": "positive regulation of protein catabolic process", "id": "GO:0045732", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045732", "evidence": [ { "database": "UniProtKB", "id": "A6KT88", "url": "https://www.uniprot.org/uniprotkb/A6KT88" } ], "pmid": "" }, { "name": "regulation of reactive oxygen species metabolic process", "id": "GO:2000377", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000377", "evidence": [ { "database": "UniProtKB", "id": "A6KT88", "url": "https://www.uniprot.org/uniprotkb/A6KT88" } ], "pmid": "" }, { "name": "mitotic G2 DNA damage checkpoint signaling", "id": "GO:0007095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007095", "evidence": [ { "database": "UniProtKB", "id": "A6KT88", "url": "https://www.uniprot.org/uniprotkb/A6KT88" } ], "pmid": "" }, { "name": "regulation of DNA repair", "id": "GO:0006282", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006282", "evidence": [ { "database": "UniProtKB", "id": "A6KT88", "url": "https://www.uniprot.org/uniprotkb/A6KT88" } ], "pmid": "" }, { "name": "response to protozoan", "id": "GO:0001562", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001562", "evidence": [ { "database": "UniProtKB", "id": "A6KT88", "url": "https://www.uniprot.org/uniprotkb/A6KT88" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A6KT88-1" }, { "uniprot_canonical_ac": "Q6XPU4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "Q6XPU4", "url": "https://www.uniprot.org/uniprotkb/Q6XPU4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 249, "chemical_mass": 28168.0, "gene_names": "Fcgr3a;CD16-2;Fcgr3a;Fcgr4", "protein_name": "Low affinity immunoglobulin gamma Fc region receptor III-A", "disease": [ { "disease_id": "DOID:0050908", "name": "myelodysplastic syndrome", "description": "A bone marrow cancer that is characterized by under production of white blood cells, red blood cells and platelets.", "url": "https://disease-ontology.org/term/DOID:0050908", "evidence": [ { "id": "0050908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050908" } ], "weight": 0.0 }, { "disease_id": "DOID:0060901", "name": "lymphoplasmacytic lymphoma", "description": "A B-cell lymphoma characterized by the accumulation of monoclonal cells in the bone marrow and peripheral lymphoid tissues, and associated with the production of serum immunoglobulin M (IgM) monoclonal protein.", "url": "https://disease-ontology.org/term/DOID:0060901", "evidence": [ { "id": "0060901", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060901" } ], "weight": 0.0 }, { "disease_id": "DOID:0080162", "name": "lupus nephritis", "description": "A glomerulonephritis that is characterized by inflammation of the kidneys resulting from systemic lupus erythematosus.", "url": "https://disease-ontology.org/term/DOID:0080162", "evidence": [ { "id": "0080162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080162" } ], "weight": 0.0 }, { "disease_id": "DOID:0081267", "name": "graft-versus-host disease", "description": "An immune system disease that is characterized by recognition by mature donor T cells, that contaminate the allogeneic bone marrow, of the recipient's tissue as foreign, causing a severe inflammatory disease characterized by rashes, diarrhea, and liver disease, and that has_material_basis_in an associated with variation in the interleukin-10 gene (IL10) on chromosome 1q32.", "url": "https://disease-ontology.org/term/DOID:0081267", "evidence": [ { "id": "0081267", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081267" } ], "weight": 0.0 }, { "disease_id": "DOID:0111941", "name": "immunodeficiency 20", "description": "A primary immunodeficiency disease characterized by a defect in spontaneous NK cell cytotoxicity that has_material_basis_in homozygous or compound heterozygous mutation in the FCGR3A gene on chromosome 1q23.3.", "url": "https://disease-ontology.org/term/DOID:0111941", "evidence": [ { "id": "0111941", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111941" } ], "weight": 0.0 }, { "disease_id": "DOID:1205", "name": "allergic disease", "description": "An immune system disease that is an exaggerated immune response to allergens, such as insect venom, dust mites, pollen, pet dander, drugs or some foods.", "url": "https://disease-ontology.org/term/DOID:1205", "evidence": [ { "id": "1205", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1205" } ], "weight": 0.0 }, { "disease_id": "DOID:13241", "name": "Behcet's disease", "description": "An autoimmune disease that is characterized by mucocutaneous manifestations, including recurrent oral and genital ulcerations, ocular manifestations, especially chronic relapsing uveitis, and systemic vasculitis involving arteries and veins of all sizes.", "url": "https://disease-ontology.org/term/DOID:13241", "evidence": [ { "id": "13241", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13241" } ], "weight": 0.0 }, { "disease_id": "DOID:13375", "name": "temporal arteritis", "description": "A central nervous system vasculitis that is characterized by inflammation of the lining of arteries, often arteries in the head.", "url": "https://disease-ontology.org/term/DOID:13375", "evidence": [ { "id": "13375", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13375" } ], "weight": 0.0 }, { "disease_id": "DOID:1389", "name": "polyneuropathy", "description": "A peripheral system disease that is characterized by damage affecting peripheral nerves (peripheral neuropathy) in roughly the same areas on both sides of the body, featuring weakness, numbness, pins-and-needles, and burning pain.", "url": "https://disease-ontology.org/term/DOID:1389", "evidence": [ { "id": "1389", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1389" } ], "weight": 0.0 }, { "disease_id": "DOID:1587", "name": "thrombocytopenia due to platelet alloimmunization", "description": "", "url": "https://disease-ontology.org/term/DOID:1587", "evidence": [ { "id": "1587", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1587" } ], "weight": 0.0 }, { "disease_id": "DOID:1826", "name": "epilepsy", "description": "A brain disease that is characterized by the occurrance of at least two unprovoked seizures resulting from a persistent epileptogenic abnormality of the brain that is able to spontaneously generate paroxysmal activity and typically manifested by sudden brief episodes of altered or diminished consciousness, involuntary movements, or convulsions.", "url": "https://disease-ontology.org/term/DOID:1826", "evidence": [ { "id": "1826", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1826" } ], "weight": 0.0 }, { "disease_id": "DOID:2377", "name": "multiple sclerosis", "description": "A demyelinating disease that involves damage to the fatty myelin sheaths around the axons of the brain and spinal cord resulting in demyelination and scarring.", "url": "https://disease-ontology.org/term/DOID:2377", "evidence": [ { "id": "2377", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2377" } ], "weight": 0.0 }, { "disease_id": "DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.", "url": "https://disease-ontology.org/term/DOID:2841", "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ], "weight": 0.0 }, { "disease_id": "DOID:2986", "name": "IgA glomerulonephritis", "description": "A glomerulonephritis characterized by build up of IgA antibody in the glomerulus.", "url": "https://disease-ontology.org/term/DOID:2986", "evidence": [ { "id": "2986", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2986" } ], "weight": 0.0 }, { "disease_id": "DOID:3393", "name": "coronary artery disease", "description": "An artery disease that is characterized by plaque building up along the inner walls of the arteries of the heart resulting in a narrowing of the arteries and a reduced blood supply to the cardiac muscles.", "url": "https://disease-ontology.org/term/DOID:3393", "evidence": [ { "id": "3393", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3393" } ], "weight": 0.0 }, { "disease_id": "DOID:4481", "name": "allergic rhinitis", "description": "A rhinitis that is an allergic inflammation and irritation of the nasal airways involving sneezing, runny nose, nasal congestion, itching and tearing of the eyes caused by exposure to an allergen such as pollen, dust, mold, animal dander and droppings of cockroaches or house dust mites.", "url": "https://disease-ontology.org/term/DOID:4481", "evidence": [ { "id": "4481", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4481" } ], "weight": 0.0 }, { "disease_id": "DOID:4780", "name": "anti-basement membrane glomerulonephritis", "description": "A Goodpasture syndrome that is characterized by damage to only kidney capillaries.", "url": "https://disease-ontology.org/term/DOID:4780", "evidence": [ { "id": "4780", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4780" } ], "weight": 0.0 }, { "disease_id": "DOID:526", "name": "human immunodeficiency virus infectious disease", "description": "A viral infectious disease that results in destruction of immune system, leading to life-threatening opportunistic infections and cancers, has_material_basis_in Human immunodeficiency virus 1 (Lentivirus humimdef1) or Human immunodeficiency virus 2 (Lentivirus humimdef2), which are transmitted by sexual contact, transmitted by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted by congenital method, and transmitted by contaminated needles. The virus infects helper T cells (CD4+ T cells) which are directly or indirectly destroyed, macrophages, and dendritic cells. The infection has symptom diarrhea, has symptom fatigue, has symptom fever, has symptom vaginal yeast infection, has symptom headache, has symptom mouth sores, has symptom muscle aches, has symptom sore throat, and has symptom swollen lymph glands.", "url": "https://disease-ontology.org/term/DOID:526", "evidence": [ { "id": "526", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:526" } ], "weight": 0.0 }, { "disease_id": "DOID:552", "name": "pneumonia", "description": "A lung disease that involves lung parenchyma or alveolar inflammation and abnormal alveolar filling with fluid (consolidation and exudation). It results from a variety of causes including infection with bacteria, viruses, fungi or parasites, and chemical or physical injury to the lungs. It is accompanied by fever, chills, cough, and difficulty in breathing.", "url": "https://disease-ontology.org/term/DOID:552", "evidence": [ { "id": "552", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:552" } ], "weight": 0.0 }, { "disease_id": "DOID:614", "name": "lymphopenia", "description": "A leukopenia that is the condition of having an abnormally low level of lymphocytes in the blood.", "url": "https://disease-ontology.org/term/DOID:614", "evidence": [ { "id": "614", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:614" } ], "weight": 0.0 }, { "disease_id": "DOID:633", "name": "myositis", "description": "A myopathy characterized by muscle inflammation.", "url": "https://disease-ontology.org/term/DOID:633", "evidence": [ { "id": "633", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:633" } ], "weight": 0.0 }, { "disease_id": "DOID:7147", "name": "ankylosing spondylitis", "description": "An arthritis that results_in inflammation in the joints of the spine and pelvis. The disease has_symptom pain, has_symptom stiffness in the spine, has_symptom stiffness in the neck, has_symptom stiffness in the hips, has_symptom stiffness in the jaw and has_symptom stiffness in the rib cage.", "url": "https://disease-ontology.org/term/DOID:7147", "evidence": [ { "id": "7147", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7147" } ], "weight": 0.0 }, { "disease_id": "DOID:7148", "name": "rheumatoid arthritis", "description": "An arthritis that is an autoimmune disease which attacks healthy cells and tissue located_in joint.", "url": "https://disease-ontology.org/term/DOID:7148", "evidence": [ { "id": "7148", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7148" } ], "weight": 0.0 }, { "disease_id": "DOID:848", "name": "arthritis", "description": "A bone inflammation disease that involves a response to irritation or injury, characterized by joint pain, swelling, stiffness located_in joint.", "url": "https://disease-ontology.org/term/DOID:848", "evidence": [ { "id": "848", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:848" } ], "weight": 0.0 }, { "disease_id": "DOID:8778", "name": "Crohn's disease", "description": "An intestinal disease that involves inflammation located_in intestine.", "url": "https://disease-ontology.org/term/DOID:8778", "evidence": [ { "id": "8778", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8778" } ], "weight": 0.0 }, { "disease_id": "DOID:8924", "name": "autoimmune thrombocytopenic purpura", "description": "A primary thrombocytopenia that involves relatively few platelets in blood as a result of autoantibodies.", "url": "https://disease-ontology.org/term/DOID:8924", "evidence": [ { "id": "8924", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8924" } ], "weight": 0.0 }, { "disease_id": "DOID:9074", "name": "systemic lupus erythematosus", "description": "A lupus erythematosus that is an inflammation of connective tissue marked by skin rashes, joint pain and swelling, inflammation of the kidneys and inflammation of the tissue surrounding the heart.", "url": "https://disease-ontology.org/term/DOID:9074", "evidence": [ { "id": "9074", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9074" } ], "weight": 0.0 } ], "biological_process": [ { "name": "Fc-gamma receptor signaling pathway", "id": "GO:0038094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038094", "evidence": [ { "database": "UniProtKB", "id": "Q6XPU4", "url": "https://www.uniprot.org/uniprotkb/Q6XPU4" } ], "pmid": "" }, { "name": "dendritic cell antigen processing and presentation", "id": "GO:0002468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002468", "evidence": [ { "database": "UniProtKB", "id": "Q6XPU4", "url": "https://www.uniprot.org/uniprotkb/Q6XPU4" } ], "pmid": "" }, { "name": "cell surface receptor signaling pathway", "id": "GO:0007166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007166", "evidence": [ { "database": "UniProtKB", "id": "Q6XPU4", "url": "https://www.uniprot.org/uniprotkb/Q6XPU4" } ], "pmid": "" }, { "name": "calcium-mediated signaling", "id": "GO:0019722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019722", "evidence": [ { "database": "UniProtKB", "id": "Q6XPU4", "url": "https://www.uniprot.org/uniprotkb/Q6XPU4" } ], "pmid": "" }, { "name": "positive regulation of bone resorption", "id": "GO:0045780", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045780", "evidence": [ { "database": "UniProtKB", "id": "Q6XPU4", "url": "https://www.uniprot.org/uniprotkb/Q6XPU4" } ], "pmid": "" }, { "name": "cellular response to lipopolysaccharide", "id": "GO:0071222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071222", "evidence": [ { "database": "UniProtKB", "id": "Q6XPU4", "url": "https://www.uniprot.org/uniprotkb/Q6XPU4" } ], "pmid": "" }, { "name": "positive regulation of tumor necrosis factor production", "id": "GO:0032760", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032760", "evidence": [ { "database": "UniProtKB", "id": "Q6XPU4", "url": "https://www.uniprot.org/uniprotkb/Q6XPU4" } ], "pmid": "" }, { "name": "phosphatidylinositol 3-kinase/protein kinase B signal transduction", "id": "GO:0043491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043491", "evidence": [ { "database": "UniProtKB", "id": "Q6XPU4", "url": "https://www.uniprot.org/uniprotkb/Q6XPU4" } ], "pmid": "" }, { "name": "natural killer cell activation", "id": "GO:0030101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030101", "evidence": [ { "database": "UniProtKB", "id": "Q6XPU4", "url": "https://www.uniprot.org/uniprotkb/Q6XPU4" } ], "pmid": "" }, { "name": "neutrophil activation", "id": "GO:0042119", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042119", "evidence": [ { "database": "UniProtKB", "id": "Q6XPU4", "url": "https://www.uniprot.org/uniprotkb/Q6XPU4" } ], "pmid": "" }, { "name": "macrophage activation", "id": "GO:0042116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042116", "evidence": [ { "database": "UniProtKB", "id": "Q6XPU4", "url": "https://www.uniprot.org/uniprotkb/Q6XPU4" } ], "pmid": "" }, { "name": "natural killer cell mediated cytotoxicity", "id": "GO:0042267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042267", "evidence": [ { "database": "UniProtKB", "id": "Q6XPU4", "url": "https://www.uniprot.org/uniprotkb/Q6XPU4" } ], "pmid": "" }, { "name": "positive regulation of natural killer cell proliferation", "id": "GO:0032819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032819", "evidence": [ { "database": "UniProtKB", "id": "Q6XPU4", "url": "https://www.uniprot.org/uniprotkb/Q6XPU4" } ], "pmid": "" }, { "name": "natural killer cell degranulation", "id": "GO:0043320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043320", "evidence": [ { "database": "UniProtKB", "id": "Q6XPU4", "url": "https://www.uniprot.org/uniprotkb/Q6XPU4" } ], "pmid": "" }, { "name": "antibody-dependent cellular cytotoxicity", "id": "GO:0001788", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001788", "evidence": [ { "database": "UniProtKB", "id": "Q6XPU4", "url": "https://www.uniprot.org/uniprotkb/Q6XPU4" } ], "pmid": "" }, { "name": "Fc receptor-mediated immune complex endocytosis", "id": "GO:0160006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160006", "evidence": [ { "database": "UniProtKB", "id": "Q6XPU4", "url": "https://www.uniprot.org/uniprotkb/Q6XPU4" } ], "pmid": "" } ], "molecular_function": [ { "name": "IgE receptor activity", "id": "GO:0019767", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019767", "evidence": [ { "database": "UniProtKB", "id": "Q6XPU4", "url": "https://www.uniprot.org/uniprotkb/Q6XPU4" } ], "pmid": "" }, { "name": "IgE binding", "id": "GO:0019863", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019863", "evidence": [ { "database": "UniProtKB", "id": "Q6XPU4", "url": "https://www.uniprot.org/uniprotkb/Q6XPU4" } ], "pmid": "" }, { "name": "IgG binding", "id": "GO:0019864", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019864", "evidence": [ { "database": "UniProtKB", "id": "Q6XPU4", "url": "https://www.uniprot.org/uniprotkb/Q6XPU4" } ], "pmid": "" }, { "name": "IgG receptor activity", "id": "GO:0019770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019770", "evidence": [ { "database": "UniProtKB", "id": "Q6XPU4", "url": "https://www.uniprot.org/uniprotkb/Q6XPU4" } ], "pmid": "" }, { "name": "low-affinity IgG receptor activity", "id": "GO:0019772", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019772", "evidence": [ { "database": "UniProtKB", "id": "Q6XPU4", "url": "https://www.uniprot.org/uniprotkb/Q6XPU4" } ], "pmid": "" }, { "name": "immune receptor activity", "id": "GO:0140375", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140375", "evidence": [ { "database": "UniProtKB", "id": "Q6XPU4", "url": "https://www.uniprot.org/uniprotkb/Q6XPU4" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q6XPU4", "url": "https://www.uniprot.org/uniprotkb/Q6XPU4" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q6XPU4", "url": "https://www.uniprot.org/uniprotkb/Q6XPU4" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "Q6XPU4", "url": "https://www.uniprot.org/uniprotkb/Q6XPU4" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "Q6XPU4", "url": "https://www.uniprot.org/uniprotkb/Q6XPU4" } ], "pmid": "" }, { "name": "Fc-gamma receptor III complex", "id": "GO:0033001", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033001", "evidence": [ { "database": "UniProtKB", "id": "Q6XPU4", "url": "https://www.uniprot.org/uniprotkb/Q6XPU4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6XPU4-1", "start_pos": "179", "end_pos": "179", "site_lbl": "Asn179", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 179, "start_aa": "Asn", "end_pos": 179, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn179", "evidence": [ { "id": "Q6XPU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6XPU4#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q6XPU4-1", "start_pos": "55", "end_pos": "55", "site_lbl": "Asn55", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 55, "start_aa": "Asn", "end_pos": 55, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn55", "evidence": [ { "id": "Q6XPU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6XPU4#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q6XPU4-1", "start_pos": "62", "end_pos": "62", "site_lbl": "Asn62", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 62, "start_aa": "Asn", "end_pos": 62, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn62", "evidence": [ { "id": "Q6XPU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6XPU4#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q6XPU4-1", "start_pos": "235", "end_pos": "235", "site_lbl": "Tyr235", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q6XPU4", "url": "https://www.uniprot.org/uniprotkb/Q6XPU4" } ] } ] } ], "record_id": "Q6XPU4-1" }, { "uniprot_canonical_ac": "A0A8I5Y0Y2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y0Y2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y0Y2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 986, "chemical_mass": 106033.0, "gene_names": "Ddi2;Ddi2;RGD1311815", "protein_name": "", "disease": [ { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y0Y2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y0Y2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y0Y2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y0Y2" } ], "pmid": "" } ], "biological_process": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y0Y2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y0Y2" } ], "pmid": "" }, { "name": "protein processing", "id": "GO:0016485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016485", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y0Y2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y0Y2" } ], "pmid": "" }, { "name": "regulation of protein stability", "id": "GO:0031647", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031647", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y0Y2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y0Y2" } ], "pmid": "" }, { "name": "proteasomal protein catabolic process", "id": "GO:0010498", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010498", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y0Y2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y0Y2" } ], "pmid": "" }, { "name": "regulation of DNA stability", "id": "GO:0097752", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097752", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y0Y2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y0Y2" } ], "pmid": "" }, { "name": "cellular response to hydroxyurea", "id": "GO:0072711", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072711", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y0Y2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y0Y2" } ], "pmid": "" }, { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y0Y2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y0Y2" } ], "pmid": "" } ], "molecular_function": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y0Y2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y0Y2" } ], "pmid": "" }, { "name": "ubiquitin binding", "id": "GO:0043130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043130", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y0Y2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y0Y2" } ], "pmid": "" }, { "name": "aspartic-type endopeptidase activity", "id": "GO:0004190", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004190", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y0Y2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y0Y2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5Y0Y2-1" }, { "uniprot_canonical_ac": "A0A8I5Y7I2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y7I2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y7I2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 327, "chemical_mass": 35874.0, "gene_names": "Kctd12;Kctd12", "protein_name": "", "disease": [], "cellular_component": [ { "name": "GABA-ergic synapse", "id": "GO:0098982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098982", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y7I2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y7I2" } ], "pmid": "" }, { "name": "presynaptic active zone membrane", "id": "GO:0048787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048787", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y7I2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y7I2" } ], "pmid": "" }, { "name": "receptor complex", "id": "GO:0043235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043235", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y7I2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y7I2" } ], "pmid": "" }, { "name": "postsynaptic membrane", "id": "GO:0045211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045211", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y7I2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y7I2" } ], "pmid": "" }, { "name": "presynaptic membrane", "id": "GO:0042734", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042734", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y7I2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y7I2" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y7I2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y7I2" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y7I2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y7I2" } ], "pmid": "" }, { "name": "G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential", "id": "GO:0099579", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099579", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y7I2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y7I2" } ], "pmid": "" }, { "name": "G protein-coupled neurotransmitter receptor activity involved in regulation of presynaptic membrane potential", "id": "GO:0150047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0150047", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y7I2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y7I2" } ], "pmid": "" } ], "biological_process": [ { "name": "protein homooligomerization", "id": "GO:0051260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051260", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y7I2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y7I2" } ], "pmid": "" }, { "name": "regulation of G protein-coupled receptor signaling pathway", "id": "GO:0008277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008277", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y7I2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y7I2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I5Y7I2-1", "start_pos": "47", "end_pos": "47", "site_lbl": "Thr47", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 47, "start_aa": "Thr", "end_pos": 47, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr47", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I5Y7I2-1" }, { "uniprot_canonical_ac": "A0A8I5Y8A9-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y8A9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y8A9" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 329, "chemical_mass": 35896.0, "gene_names": "Gltpd2", "protein_name": "", "disease": [], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y8A9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y8A9" } ], "pmid": "" } ], "biological_process": [ { "name": "ceramide transport", "id": "GO:0035627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035627", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y8A9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y8A9" } ], "pmid": "" }, { "name": "negative regulation of interleukin-1 beta production", "id": "GO:0032691", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032691", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y8A9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y8A9" } ], "pmid": "" }, { "name": "intermembrane lipid transfer", "id": "GO:0120009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120009", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y8A9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y8A9" } ], "pmid": "" } ], "molecular_function": [ { "name": "ceramide 1-phosphate binding", "id": "GO:1902387", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902387", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y8A9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y8A9" } ], "pmid": "" }, { "name": "ceramide 1-phosphate transfer activity", "id": "GO:1902388", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902388", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y8A9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y8A9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5Y8A9-1" }, { "uniprot_canonical_ac": "A0A8I5Y8G0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y8G0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y8G0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 179, "chemical_mass": 18847.0, "gene_names": "C1h19orf84;C1h19orf84", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y8G0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y8G0" } ], "pmid": "" } ], "biological_process": [ { "name": "transposable element silencing by piRNA-mediated DNA methylation", "id": "GO:0141196", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141196", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y8G0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y8G0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I5Y8G0-1", "start_pos": "158", "end_pos": "158", "site_lbl": "Thr158", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 158, "start_aa": "Thr", "end_pos": 158, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr158", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I5Y8G0-1", "start_pos": "30", "end_pos": "30", "site_lbl": "Thr30", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 30, "start_aa": "Thr", "end_pos": 30, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr30", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I5Y8G0-1" }, { "uniprot_canonical_ac": "A0A8I5YBS6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YBS6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YBS6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 603, "chemical_mass": 70107.0, "gene_names": "ENSRNOG00000069312;Zfp120l2", "protein_name": "", "disease": [], "biological_process": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YBS6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YBS6" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YBS6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YBS6" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YBS6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YBS6" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YBS6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YBS6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5YBS6-1" }, { "uniprot_canonical_ac": "A0A8I5YC61-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YC61", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YC61" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 351, "chemical_mass": 38065.0, "gene_names": "Eno1-ps20", "protein_name": "phosphopyruvate hydratase", "disease": [], "molecular_function": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YC61", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YC61" } ], "pmid": "" }, { "name": "phosphopyruvate hydratase activity", "id": "GO:0004634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YC61", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YC61" } ], "pmid": "" } ], "biological_process": [ { "name": "glycolytic process", "id": "GO:0006096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006096", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YC61", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YC61" } ], "pmid": "" } ], "cellular_component": [ { "name": "phosphopyruvate hydratase complex", "id": "GO:0000015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000015", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5YC61", "url": "https://www.uniprot.org/uniprotkb/A0A8I5YC61" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5YC61-1" }, { "uniprot_canonical_ac": "A0A8I5ZJM6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZJM6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZJM6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 115, "chemical_mass": 12655.0, "gene_names": "Igkv5-45l1", "protein_name": "", "disease": [], "biological_process": [ { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZJM6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZJM6" } ], "pmid": "" } ], "cellular_component": [ { "name": "immunoglobulin complex", "id": "GO:0019814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019814", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZJM6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZJM6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I5ZJM6-1", "start_pos": "34", "end_pos": "34", "site_lbl": "Thr34", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 34, "start_aa": "Thr", "end_pos": 34, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr34", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I5ZJM6-1" }, { "uniprot_canonical_ac": "A0A8I5ZKU6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZKU6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZKU6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 145, "chemical_mass": 16076.0, "gene_names": "ENSRNOG00000063949", "protein_name": "Ig-like domain-containing protein", "disease": [], "cellular_component": [ { "name": "T cell receptor complex", "id": "GO:0042101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042101", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZKU6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZKU6" } ], "pmid": "" } ], "biological_process": [ { "name": "adaptive immune response", "id": "GO:0002250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002250", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZKU6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZKU6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZKU6-1" }, { "uniprot_canonical_ac": "A0A8I5ZKZ0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZKZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZKZ0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 913, "chemical_mass": 99225.0, "gene_names": "Znrf3", "protein_name": "E3 ubiquitin-protein ligase ZNRF3", "disease": [], "biological_process": [ { "name": "regulation of Wnt signaling pathway, planar cell polarity pathway", "id": "GO:2000095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000095", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZKZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZKZ0" } ], "pmid": "" }, { "name": "negative regulation of canonical Wnt signaling pathway", "id": "GO:0090090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090090", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZKZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZKZ0" } ], "pmid": "" }, { "name": "Wnt signaling pathway", "id": "GO:0016055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZKZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZKZ0" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZKZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZKZ0" } ], "pmid": "" }, { "name": "negative regulation of Wnt signaling pathway", "id": "GO:0030178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030178", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZKZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZKZ0" } ], "pmid": "" }, { "name": "regulation of canonical Wnt signaling pathway", "id": "GO:0060828", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060828", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZKZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZKZ0" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZKZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZKZ0" } ], "pmid": "" }, { "name": "stem cell proliferation", "id": "GO:0072089", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072089", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZKZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZKZ0" } ], "pmid": "" }, { "name": "Wnt receptor catabolic process", "id": "GO:0038018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038018", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZKZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZKZ0" } ], "pmid": "" }, { "name": "negative regulation of non-canonical Wnt signaling pathway", "id": "GO:2000051", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000051", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZKZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZKZ0" } ], "pmid": "" }, { "name": "regulation of non-canonical Wnt signaling pathway", "id": "GO:2000050", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000050", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZKZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZKZ0" } ], "pmid": "" } ], "molecular_function": [ { "name": "frizzled binding", "id": "GO:0005109", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005109", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZKZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZKZ0" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZKZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZKZ0" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZKZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZKZ0" } ], "pmid": "" }, { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZKZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZKZ0" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZKZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZKZ0" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZKZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZKZ0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I5ZKZ0-1", "start_pos": "488", "end_pos": "488", "site_lbl": "Thr488", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 488, "start_aa": "Thr", "end_pos": 488, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr488", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I5ZKZ0-1", "start_pos": "708", "end_pos": "708", "site_lbl": "Thr708", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 708, "start_aa": "Thr", "end_pos": 708, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr708", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I5ZKZ0-1" }, { "uniprot_canonical_ac": "A0A8I5ZL56-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZL56", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZL56" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 276, "chemical_mass": 30309.0, "gene_names": "Nfilz;Nfilz", "protein_name": "E4 promoter-binding protein 4", "disease": [], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZL56", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZL56" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZL56", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZL56" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZL56", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZL56" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZL56", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZL56" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZL56", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZL56" } ], "pmid": "" }, { "name": "circadian rhythm", "id": "GO:0007623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007623", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZL56", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZL56" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZL56-1" }, { "uniprot_canonical_ac": "A0A8I5ZLJ0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZLJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZLJ0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 220, "chemical_mass": 26167.0, "gene_names": "ENSRNOG00000068876", "protein_name": "Gem-associated protein 8", "disease": [], "biological_process": [ { "name": "spliceosomal snRNP assembly", "id": "GO:0000387", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000387", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZLJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZLJ0" } ], "pmid": "" } ], "cellular_component": [ { "name": "SMN complex", "id": "GO:0032797", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032797", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZLJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZLJ0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZLJ0-1" }, { "uniprot_canonical_ac": "A0A8I5ZLT9-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZLT9", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZLT9" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 198, "chemical_mass": 22822.0, "gene_names": "Atp6v1fnbl;AC093960.1;Atp6v1fnbl;LOC108353015", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZLT9-1" }, { "uniprot_canonical_ac": "A0A8I5ZN60-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN60", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN60" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 147, "chemical_mass": 16617.0, "gene_names": "ENSRNOG00000069193", "protein_name": "Ig-like domain-containing protein", "disease": [], "biological_process": [ { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN60", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN60" } ], "pmid": "" } ], "cellular_component": [ { "name": "immunoglobulin complex", "id": "GO:0019814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019814", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZN60", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZN60" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZN60-1" }, { "uniprot_canonical_ac": "A0A8I5ZPC5-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZPC5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZPC5" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 106, "chemical_mass": 11910.0, "gene_names": "ENSRNOG00000065156", "protein_name": "Immunoglobulin V-set domain-containing protein", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZPC5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZPC5" } ], "pmid": "" }, { "name": "immunoglobulin complex", "id": "GO:0019814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019814", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZPC5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZPC5" } ], "pmid": "" } ], "molecular_function": [ { "name": "antigen binding", "id": "GO:0003823", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003823", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZPC5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZPC5" } ], "pmid": "" } ], "biological_process": [ { "name": "immunoglobulin mediated immune response", "id": "GO:0016064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016064", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZPC5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZPC5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZPC5-1" }, { "uniprot_canonical_ac": "A0A8I5ZPD4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZPD4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZPD4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 115, "chemical_mass": 12708.0, "gene_names": "ENSRNOG00000063938", "protein_name": "Ig-like domain-containing protein", "disease": [], "cellular_component": [ { "name": "T cell receptor complex", "id": "GO:0042101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042101", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZPD4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZPD4" } ], "pmid": "" } ], "biological_process": [ { "name": "adaptive immune response", "id": "GO:0002250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002250", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZPD4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZPD4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZPD4-1" }, { "uniprot_canonical_ac": "A0A8I5ZS21-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZS21", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZS21" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 652, "chemical_mass": 73356.0, "gene_names": "Traf3ip2", "protein_name": "E3 ubiquitin ligase TRAF3IP2", "disease": [ { "disease_id": "DOID:0111287", "name": "psoriasis 13", "description": "A psoriasis that has_material_basis_in variation in the TRAF3IP2 gene on chromosome 6q21.", "url": "https://disease-ontology.org/term/DOID:0111287", "evidence": [ { "id": "0111287", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111287" } ], "weight": 0.0 }, { "disease_id": "DOID:12894", "name": "Sjogren's syndrome", "description": "An autoimmune disease that involves attack of immune cells which destroy the exocrine glands that produce tears and saliva.", "url": "https://disease-ontology.org/term/DOID:12894", "evidence": [ { "id": "12894", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12894" } ], "weight": 0.0 }, { "disease_id": "DOID:2058", "name": "chronic mucocutaneous candidiasis", "description": "A candidiasis that refers to a heterogeneous group of disorders characterized by recurrent or persistent superficial fungal infections located_in skin, located_in mucous membrane, or located_in nail due to T-cell defects, has-agent Candida species and has_symptom scaling of skin lesions, has_symptom thickening of nails, has_symptom swollen periungal tissue, and has_symptom scarring of the scalp.", "url": "https://disease-ontology.org/term/DOID:2058", "evidence": [ { "id": "2058", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2058" } ], "weight": 0.0 }, { "disease_id": "DOID:3310", "name": "atopic dermatitis", "description": "An allergic contact dermatitis that is a chronically relapsing inflammatory allergic response located_in the skin that causes itching and flaking.", "url": "https://disease-ontology.org/term/DOID:3310", "evidence": [ { "id": "3310", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3310" } ], "weight": 0.0 }, { "disease_id": "DOID:9074", "name": "systemic lupus erythematosus", "description": "A lupus erythematosus that is an inflammation of connective tissue marked by skin rashes, joint pain and swelling, inflammation of the kidneys and inflammation of the tissue surrounding the heart.", "url": "https://disease-ontology.org/term/DOID:9074", "evidence": [ { "id": "9074", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9074" } ], "weight": 0.0 } ], "biological_process": [ { "name": "CD40 signaling pathway", "id": "GO:0023035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0023035", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZS21", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZS21" } ], "pmid": "" }, { "name": "inflammatory response", "id": "GO:0006954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006954", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZS21", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZS21" } ], "pmid": "" }, { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZS21", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZS21" } ], "pmid": "" }, { "name": "heart development", "id": "GO:0007507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007507", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZS21", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZS21" } ], "pmid": "" }, { "name": "mRNA stabilization", "id": "GO:0048255", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048255", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZS21", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZS21" } ], "pmid": "" }, { "name": "kidney development", "id": "GO:0001822", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001822", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZS21", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZS21" } ], "pmid": "" }, { "name": "T cell activation", "id": "GO:0042110", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042110", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZS21", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZS21" } ], "pmid": "" }, { "name": "positive regulation of canonical NF-kappaB signal transduction", "id": "GO:0043123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043123", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZS21", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZS21" } ], "pmid": "" }, { "name": "response to cytokine", "id": "GO:0034097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034097", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZS21", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZS21" } ], "pmid": "" }, { "name": "spleen development", "id": "GO:0048536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048536", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZS21", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZS21" } ], "pmid": "" }, { "name": "mucus secretion", "id": "GO:0070254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070254", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZS21", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZS21" } ], "pmid": "" }, { "name": "positive regulation of defense response to virus by host", "id": "GO:0002230", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002230", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZS21", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZS21" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZS21", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZS21" } ], "pmid": "" }, { "name": "protein localization to nucleus", "id": "GO:0034504", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034504", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZS21", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZS21" } ], "pmid": "" }, { "name": "skin development", "id": "GO:0043588", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043588", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZS21", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZS21" } ], "pmid": "" }, { "name": "protein polyubiquitination", "id": "GO:0000209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000209", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZS21", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZS21" } ], "pmid": "" }, { "name": "cellular response to cytokine stimulus", "id": "GO:0071345", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071345", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZS21", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZS21" } ], "pmid": "" }, { "name": "humoral immune response", "id": "GO:0006959", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006959", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZS21", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZS21" } ], "pmid": "" }, { "name": "response to xenobiotic stimulus", "id": "GO:0009410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009410", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZS21", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZS21" } ], "pmid": "" }, { "name": "tumor necrosis factor-mediated signaling pathway", "id": "GO:0033209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033209", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZS21", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZS21" } ], "pmid": "" }, { "name": "protein K63-linked ubiquitination", "id": "GO:0070534", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070534", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZS21", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZS21" } ], "pmid": "" }, { "name": "B cell homeostasis", "id": "GO:0001782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001782", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZS21", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZS21" } ], "pmid": "" }, { "name": "B cell apoptotic process", "id": "GO:0001783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001783", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZS21", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZS21" } ], "pmid": "" }, { "name": "cytokine-mediated signaling pathway", "id": "GO:0019221", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019221", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZS21", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZS21" } ], "pmid": "" }, { "name": "T cell differentiation", "id": "GO:0030217", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030217", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZS21", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZS21" } ], "pmid": "" }, { "name": "neutrophil activation", "id": "GO:0042119", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042119", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZS21", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZS21" } ], "pmid": "" }, { "name": "gene expression", "id": "GO:0010467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010467", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZS21", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZS21" } ], "pmid": "" }, { "name": "type 2 immune response", "id": "GO:0042092", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042092", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZS21", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZS21" } ], "pmid": "" }, { "name": "B cell affinity maturation", "id": "GO:0002344", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002344", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZS21", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZS21" } ], "pmid": "" }, { "name": "establishment of T cell polarity", "id": "GO:0001768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001768", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZS21", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZS21" } ], "pmid": "" }, { "name": "lymph node development", "id": "GO:0048535", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048535", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZS21", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZS21" } ], "pmid": "" }, { "name": "B cell mediated immunity", "id": "GO:0019724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019724", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZS21", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZS21" } ], "pmid": "" }, { "name": "protein import into nucleus", "id": "GO:0006606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006606", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZS21", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZS21" } ], "pmid": "" }, { "name": "cellular response to interleukin-17", "id": "GO:0097398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097398", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZS21", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZS21" } ], "pmid": "" }, { "name": "protein localization to P-body", "id": "GO:0110012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0110012", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZS21", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZS21" } ], "pmid": "" }, { "name": "transitional two stage B cell differentiation", "id": "GO:0002334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002334", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZS21", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZS21" } ], "pmid": "" }, { "name": "eosinophil mediated immunity", "id": "GO:0002447", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002447", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZS21", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZS21" } ], "pmid": "" }, { "name": "interleukin-17A-mediated signaling pathway", "id": "GO:0038173", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038173", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZS21", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZS21" } ], "pmid": "" }, { "name": "eosinophil homeostasis", "id": "GO:1990959", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990959", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZS21", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZS21" } ], "pmid": "" }, { "name": "interleukin-17-mediated signaling pathway", "id": "GO:0097400", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097400", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZS21", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZS21" } ], "pmid": "" }, { "name": "T-helper 17 type immune response", "id": "GO:0072538", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072538", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZS21", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZS21" } ], "pmid": "" } ], "molecular_function": [ { "name": "signaling receptor binding", "id": "GO:0005102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005102", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZS21", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZS21" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZS21", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZS21" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZS21", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZS21" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZS21", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZS21" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZS21-1" }, { "uniprot_canonical_ac": "A0A8I5ZSQ5-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZSQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZSQ5" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1600, "chemical_mass": 176971.0, "gene_names": "RGD1562811", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I5ZSQ5-1", "start_pos": "111", "end_pos": "111", "site_lbl": "Thr111", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 111, "start_aa": "Thr", "end_pos": 111, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr111", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I5ZSQ5-1", "start_pos": "439", "end_pos": "439", "site_lbl": "Thr439", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 439, "start_aa": "Thr", "end_pos": 439, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr439", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I5ZSQ5-1", "start_pos": "754", "end_pos": "754", "site_lbl": "Thr754", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 754, "start_aa": "Thr", "end_pos": 754, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr754", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I5ZSQ5-1" }, { "uniprot_canonical_ac": "A0A8I5ZT52-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZT52", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZT52" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 150, "chemical_mass": 16495.0, "gene_names": "Plp2l1;AABR07067583.1;LOC685108;Plp2l1", "protein_name": "Proteolipid protein 2", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZT52", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZT52" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZT52-1" }, { "uniprot_canonical_ac": "A0A8I5ZTW6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTW6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTW6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 463, "chemical_mass": 50505.0, "gene_names": "Gopc", "protein_name": "Golgi-associated PDZ and coiled-coil motif-containing protein", "disease": [ { "disease_id": "DOID:14227", "name": "azoospermia", "description": "A male infertility disease characterized by the absence of any measurable level of sperm in semen.", "url": "https://disease-ontology.org/term/DOID:14227", "evidence": [ { "id": "14227", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14227" } ], "weight": 0.0 }, { "disease_id": "DOID:14330", "name": "Parkinson's disease", "description": "A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.", "url": "https://disease-ontology.org/term/DOID:14330", "evidence": [ { "id": "14330", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14330" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "frizzled binding", "id": "GO:0005109", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005109", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTW6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTW6" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTW6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTW6" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTW6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTW6" } ], "pmid": "" }, { "name": "transmembrane transporter binding", "id": "GO:0044325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044325", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTW6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTW6" } ], "pmid": "" }, { "name": "GTPase regulator activity", "id": "GO:0030695", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030695", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTW6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTW6" } ], "pmid": "" }, { "name": "molecular sequestering activity", "id": "GO:0140313", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140313", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTW6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTW6" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTW6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTW6" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTW6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTW6" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTW6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTW6" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTW6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTW6" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTW6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTW6" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTW6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTW6" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTW6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTW6" } ], "pmid": "" }, { "name": "trans-Golgi network transport vesicle", "id": "GO:0030140", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030140", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTW6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTW6" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTW6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTW6" } ], "pmid": "" } ], "biological_process": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTW6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTW6" } ], "pmid": "" }, { "name": "negative regulation of protein localization to cell surface", "id": "GO:2000009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000009", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTW6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTW6" } ], "pmid": "" }, { "name": "spermatid nucleus differentiation", "id": "GO:0007289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007289", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTW6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTW6" } ], "pmid": "" }, { "name": "negative regulation of anion channel activity", "id": "GO:0010360", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010360", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTW6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTW6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZTW6-1" }, { "uniprot_canonical_ac": "A0A8I5ZU81-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZU81", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZU81" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 182, "chemical_mass": 21033.0, "gene_names": "Fth1-ps5", "protein_name": "Ferritin", "disease": [ { "disease_id": "DOID:0080600", "name": "COVID-19", "description": "A Coronavirus infectious disease that is characterized by fever, cough and shortness of breath and that has_material_basis_in Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a subtype of Betacoronavirus pandemicum.", "url": "https://disease-ontology.org/term/DOID:0080600", "evidence": [ { "id": "0080600", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080600" } ], "weight": 0.0 }, { "disease_id": "DOID:0110734", "name": "neurodegeneration with brain iron accumulation", "description": "A neurodegenerative disease characterized by progressive iron accumulation in the basal ganglia and other regions of the brain, resulting in extrapyramidal movements, such as parkinsonism and dystonia.", "url": "https://disease-ontology.org/term/DOID:0110734", "evidence": [ { "id": "0110734", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110734" } ], "weight": 0.0 }, { "disease_id": "DOID:0111031", "name": "hemochromatosis type 5", "description": "A hemochromatosis that has_material_basis_in heterozygous mutation in the FTH1 gene on chromosome 11q12.", "url": "https://disease-ontology.org/term/DOID:0111031", "evidence": [ { "id": "0111031", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111031" } ], "weight": 0.0 }, { "disease_id": "DOID:1508", "name": "candidiasis", "description": "An opportunistic mycosis that involves fungal infection of the mouth, throat, skin, scalp, vagina, fingers, nails, bronchi, lungs, heart and brain by Candida species, of which Candida albicans is the most common. Systemic Candida infections are usually confined to severely immunocompromised persons.", "url": "https://disease-ontology.org/term/DOID:1508", "evidence": [ { "id": "1508", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1508" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZU81", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZU81" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZU81", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZU81" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZU81", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZU81" } ], "pmid": "" }, { "name": "autophagosome", "id": "GO:0005776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005776", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZU81", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZU81" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular iron ion homeostasis", "id": "GO:0006879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006879", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZU81", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZU81" } ], "pmid": "" }, { "name": "iron ion transport", "id": "GO:0006826", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006826", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZU81", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZU81" } ], "pmid": "" } ], "molecular_function": [ { "name": "ferrous iron binding", "id": "GO:0008198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008198", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZU81", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZU81" } ], "pmid": "" }, { "name": "ferroxidase activity", "id": "GO:0004322", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004322", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZU81", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZU81" } ], "pmid": "" }, { "name": "ferric iron binding", "id": "GO:0008199", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008199", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZU81", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZU81" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZU81-1" }, { "uniprot_canonical_ac": "A0A8I5ZUJ8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUJ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUJ8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 312, "chemical_mass": 35606.0, "gene_names": "Or1e35;Olr1873;Or1e35", "protein_name": "", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUJ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUJ8" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUJ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUJ8" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUJ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUJ8" } ], "pmid": "" } ], "biological_process": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUJ8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUJ8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZUJ8-1" }, { "uniprot_canonical_ac": "A0A8I5ZUK2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUK2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUK2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1123, "chemical_mass": 118341.0, "gene_names": "Ubap2l;Atp8b2;EP1;Ubap2l", "protein_name": "", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUK2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUK2" } ], "pmid": "" }, { "name": "PcG protein complex", "id": "GO:0031519", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031519", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUK2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUK2" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUK2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUK2" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUK2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUK2" } ], "pmid": "" } ], "biological_process": [ { "name": "binding of sperm to zona pellucida", "id": "GO:0007339", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007339", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUK2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUK2" } ], "pmid": "" }, { "name": "stress granule assembly", "id": "GO:0034063", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034063", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUK2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUK2" } ], "pmid": "" }, { "name": "positive regulation of stress granule assembly", "id": "GO:0062029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0062029", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUK2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUK2" } ], "pmid": "" }, { "name": "hematopoietic stem cell homeostasis", "id": "GO:0061484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061484", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZUK2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZUK2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I5ZUK2-1", "start_pos": "877", "end_pos": "877", "site_lbl": "Thr877", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 877, "start_aa": "Thr", "end_pos": 877, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr877", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I5ZUK2-1", "start_pos": "972", "end_pos": "972", "site_lbl": "Thr972", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 972, "start_aa": "Thr", "end_pos": 972, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr972", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I5ZUK2-1" }, { "uniprot_canonical_ac": "A0A8I5ZVX8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZVX8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZVX8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 88, "chemical_mass": 9920.0, "gene_names": "LOC102553848;AABR07036498.1", "protein_name": "Acyl-CoA-binding protein", "disease": [], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZVX8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZVX8" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZVX8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZVX8" } ], "pmid": "" } ], "biological_process": [ { "name": "fatty acid metabolic process", "id": "GO:0006631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006631", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZVX8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZVX8" } ], "pmid": "" } ], "molecular_function": [ { "name": "fatty-acyl-CoA binding", "id": "GO:0000062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000062", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZVX8", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZVX8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZVX8-1" }, { "uniprot_canonical_ac": "A0A8I5ZYA7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYA7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYA7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 313, "chemical_mass": 35566.0, "gene_names": "Or8k33;Olr508;Or8k33", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYA7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYA7" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYA7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYA7" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZYA7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZYA7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZYA7-1" }, { "uniprot_canonical_ac": "A0A8I5ZZE4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZZE4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZZE4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 421, "chemical_mass": 46840.0, "gene_names": "Rbm34-ps1", "protein_name": "", "disease": [], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZZE4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZZE4" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZZE4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZZE4" } ], "pmid": "" } ], "biological_process": [ { "name": "maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000463", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZZE4", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZZE4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZZE4-1" }, { "uniprot_canonical_ac": "A0A8I5ZZX7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZZX7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZZX7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 87, "chemical_mass": 9125.0, "gene_names": "Hmgn2l2;AABR07008421.1;LOC100362827", "protein_name": "Non-histone chromosomal protein HMG-17", "disease": [], "molecular_function": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZZX7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZZX7" } ], "pmid": "" }, { "name": "nucleosomal DNA binding", "id": "GO:0031492", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031492", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZZX7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZZX7" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZZX7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZZX7" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZZX7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZZX7" } ], "pmid": "" } ], "biological_process": [ { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZZX7", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZZX7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZZX7-1" }, { "uniprot_canonical_ac": "A0A8I6A7G4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A7G4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A7G4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 236, "chemical_mass": 25900.0, "gene_names": "Cmtm7", "protein_name": "", "disease": [], "biological_process": [ { "name": "protein phosphorylation", "id": "GO:0006468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006468", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A7G4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A7G4" } ], "pmid": "" }, { "name": "inflammatory response to antigenic stimulus", "id": "GO:0002437", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002437", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A7G4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A7G4" } ], "pmid": "" }, { "name": "B cell activation", "id": "GO:0042113", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042113", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A7G4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A7G4" } ], "pmid": "" }, { "name": "positive regulation of p38MAPK cascade", "id": "GO:1900745", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900745", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A7G4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A7G4" } ], "pmid": "" }, { "name": "toll-like receptor signaling pathway", "id": "GO:0002224", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002224", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A7G4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A7G4" } ], "pmid": "" }, { "name": "plasma cell differentiation", "id": "GO:0002317", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002317", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A7G4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A7G4" } ], "pmid": "" }, { "name": "gene expression", "id": "GO:0010467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010467", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A7G4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A7G4" } ], "pmid": "" }, { "name": "B-1a B cell differentiation", "id": "GO:0002337", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002337", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A7G4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A7G4" } ], "pmid": "" } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A7G4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A7G4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6A7G4-1" }, { "uniprot_canonical_ac": "A0A8I6A1H0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1H0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1H0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 226, "chemical_mass": 24813.0, "gene_names": "AABR07060610.1", "protein_name": "Large ribosomal subunit protein uL11", "disease": [], "biological_process": [ { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1H0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1H0" } ], "pmid": "" } ], "molecular_function": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1H0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1H0" } ], "pmid": "" }, { "name": "large ribosomal subunit rRNA binding", "id": "GO:0070180", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070180", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1H0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1H0" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosolic large ribosomal subunit", "id": "GO:0022625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022625", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1H0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1H0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6A1H0-1" }, { "uniprot_canonical_ac": "A0A8I6A1T3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1T3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1T3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 316, "chemical_mass": 34759.0, "gene_names": "Or5p52;Olfr472", "protein_name": "Olfactory receptor", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1T3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1T3" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1T3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1T3" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1T3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1T3" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1T3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1T3" } ], "pmid": "" } ], "biological_process": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1T3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1T3" } ], "pmid": "" }, { "name": "sensory perception of smell", "id": "GO:0007608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007608", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1T3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1T3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6A1T3-1" }, { "uniprot_canonical_ac": "A0A8I6A2K1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2K1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2K1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 159, "chemical_mass": 17769.0, "gene_names": "Trav12-3", "protein_name": "Ig-like domain-containing protein", "disease": [], "cellular_component": [ { "name": "T cell receptor complex", "id": "GO:0042101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042101", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2K1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2K1" } ], "pmid": "" } ], "molecular_function": [ { "name": "peptide antigen binding", "id": "GO:0042605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042605", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2K1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2K1" } ], "pmid": "" } ], "biological_process": [ { "name": "adaptive immune response", "id": "GO:0002250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002250", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2K1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2K1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6A2K1-1" }, { "uniprot_canonical_ac": "A0A8I6A2P1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2P1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2P1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 164, "chemical_mass": 19330.0, "gene_names": "Srsf3;Sfrs3;Srsf3", "protein_name": "Serine/arginine-rich splicing factor 3", "disease": [ { "disease_id": "DOID:2152", "name": "ovary epithelial cancer", "description": "An ovarian cancer that is derives_from ovarian surface epithelium.", "url": "https://disease-ontology.org/term/DOID:2152", "evidence": [ { "id": "2152", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2152" } ], "weight": 0.0 }, { "disease_id": "DOID:3312", "name": "bipolar disorder", "description": "A mood disorder that involves alternating periods of mania and depression.", "url": "https://disease-ontology.org/term/DOID:3312", "evidence": [ { "id": "3312", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3312" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "sequence-specific mRNA binding", "id": "GO:1990825", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990825", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2P1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2P1" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2P1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2P1" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2P1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2P1" } ], "pmid": "" }, { "name": "phospholipase binding", "id": "GO:0043274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043274", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2P1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2P1" } ], "pmid": "" }, { "name": "primary miRNA binding", "id": "GO:0070878", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070878", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2P1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2P1" } ], "pmid": "" }, { "name": "protein-RNA sequence-specific adaptor activity", "id": "GO:0160134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160134", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2P1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2P1" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2P1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2P1" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2P1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2P1" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA export from nucleus", "id": "GO:0006406", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006406", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2P1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2P1" } ], "pmid": "" }, { "name": "cellular response to leukemia inhibitory factor", "id": "GO:1990830", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990830", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2P1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2P1" } ], "pmid": "" }, { "name": "regulation of mRNA splicing, via spliceosome", "id": "GO:0048024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048024", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2P1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2P1" } ], "pmid": "" }, { "name": "primary miRNA processing", "id": "GO:0031053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031053", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2P1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2P1" } ], "pmid": "" }, { "name": "regulation of alternative mRNA splicing, via spliceosome", "id": "GO:0000381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000381", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A2P1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A2P1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6A2P1-1" }, { "uniprot_canonical_ac": "A0A8I6A419-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A419", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A419" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 141, "chemical_mass": 14920.0, "gene_names": "C8h3orf86;C8h3orf86", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6A419-1", "start_pos": "35", "end_pos": "35", "site_lbl": "Thr35", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 35, "start_aa": "Thr", "end_pos": 35, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr35", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6A419-1" }, { "uniprot_canonical_ac": "A0A8I6A4C1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A4C1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A4C1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 350, "chemical_mass": 36745.0, "gene_names": "ENSRNOG00000063783", "protein_name": "RRM domain-containing protein", "disease": [], "molecular_function": [ { "name": "mRNA 3'-UTR binding", "id": "GO:0003730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003730", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A4C1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A4C1" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A4C1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A4C1" } ], "pmid": "" } ], "cellular_component": [ { "name": "catalytic step 2 spliceosome", "id": "GO:0071013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071013", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A4C1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A4C1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6A4C1-1" }, { "uniprot_canonical_ac": "A0A8I6A5P2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5P2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5P2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 167, "chemical_mass": 18250.0, "gene_names": "Mosmo;Mosmo", "protein_name": "Modulator of smoothened protein", "disease": [ { "disease_id": "DOID:0060399", "name": "chromosome 16p12.1 deletion syndrome", "description": "A chromosomal deletion syndrome that has_material_basis_in a 520 kb deletion on the short (p) arm of the chromosome at a location designated 16p12.1 and is characterized by developmental delay, craniofacial dysmorphology, and congenital heart defects.", "url": "https://disease-ontology.org/term/DOID:0060399", "evidence": [ { "id": "0060399", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060399" } ], "weight": 0.0 } ], "biological_process": [ { "name": "left/right pattern formation", "id": "GO:0060972", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060972", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5P2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5P2" } ], "pmid": "" }, { "name": "in utero embryonic development", "id": "GO:0001701", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001701", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5P2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5P2" } ], "pmid": "" }, { "name": "heart development", "id": "GO:0007507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007507", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5P2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5P2" } ], "pmid": "" }, { "name": "lung development", "id": "GO:0030324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030324", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5P2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5P2" } ], "pmid": "" }, { "name": "embryonic limb morphogenesis", "id": "GO:0030326", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030326", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5P2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5P2" } ], "pmid": "" }, { "name": "regulation of neuron differentiation", "id": "GO:0045664", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045664", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5P2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5P2" } ], "pmid": "" }, { "name": "regulation of protein stability", "id": "GO:0031647", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031647", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5P2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5P2" } ], "pmid": "" }, { "name": "intracellular protein localization", "id": "GO:0008104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008104", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5P2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5P2" } ], "pmid": "" }, { "name": "smoothened signaling pathway", "id": "GO:0007224", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007224", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5P2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5P2" } ], "pmid": "" }, { "name": "gene expression", "id": "GO:0010467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010467", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5P2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5P2" } ], "pmid": "" }, { "name": "embryonic skeletal system development", "id": "GO:0048706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048706", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5P2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5P2" } ], "pmid": "" }, { "name": "negative regulation of smoothened signaling pathway", "id": "GO:0045879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045879", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5P2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5P2" } ], "pmid": "" } ], "cellular_component": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5P2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5P2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5P2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5P2" } ], "pmid": "" }, { "name": "ciliary membrane", "id": "GO:0060170", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060170", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5P2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5P2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6A5P2-1" }, { "uniprot_canonical_ac": "A0A8I6A6Q5-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A6Q5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A6Q5" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 737, "chemical_mass": 81413.0, "gene_names": "Kiaa1958;Kiaa1958;RGD1310951", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6A6Q5-1" }, { "uniprot_canonical_ac": "A0A8I6A6W9-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A6W9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A6W9" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1093, "chemical_mass": 122029.0, "gene_names": "LOC134482685", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6A6W9-1", "start_pos": "361", "end_pos": "361", "site_lbl": "Thr361", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 361, "start_aa": "Thr", "end_pos": 361, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr361", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6A6W9-1" }, { "uniprot_canonical_ac": "A0A8I6A6Y9-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A6Y9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A6Y9" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 238, "chemical_mass": 26632.0, "gene_names": "ENSRNOG00000066543", "protein_name": "RNA-binding protein PNO1", "disease": [], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A6Y9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A6Y9" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A6Y9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A6Y9" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A6Y9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A6Y9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6A6Y9-1" }, { "uniprot_canonical_ac": "A0A8I6A7B0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A7B0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A7B0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 212, "chemical_mass": 24097.0, "gene_names": "Cd300ldl1;Cd300ldl1;RGD1562156", "protein_name": "", "disease": [], "molecular_function": [ { "name": "transmembrane signaling receptor activity", "id": "GO:0004888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004888", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A7B0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A7B0" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A7B0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A7B0" } ], "pmid": "" } ], "biological_process": [ { "name": "immune response-activating signaling pathway", "id": "GO:0002757", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002757", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A7B0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A7B0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6A7B0-1" }, { "uniprot_canonical_ac": "A0A8I6AAN3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AAN3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AAN3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 795, "chemical_mass": 87329.0, "gene_names": "Aldh18a1;Aldh18a1;Pycs", "protein_name": "Delta-1-pyrroline-5-carboxylate synthase", "disease": [ { "disease_id": "DOID:0070131", "name": "autosomal dominant cutis laxa 3", "description": "An autosomal dominant cutis laxa characterized by thin skin with visible veins and wrinkles, cataract or corneal clouding, clenched fingers, pre- and postnatal growth retardation, moderate intellectual disability, and a combination of muscle hypotonia with brisk muscle reflexes that has_material_basis_in heterozygous mutation in the ALDH18A1 gene on chromosome 10q24.", "url": "https://disease-ontology.org/term/DOID:0070131", "evidence": [ { "id": "0070131", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070131" } ], "weight": 0.0 }, { "disease_id": "DOID:0070132", "name": "autosomal recessive cutis laxa type IIIA", "description": "A autosomal recessive cutis laxa type III that has_material_basis_in homozygous mutation in the ALDH18A1 gene on chromosome 10q24.", "url": "https://disease-ontology.org/term/DOID:0070132", "evidence": [ { "id": "0070132", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070132" } ], "weight": 0.0 }, { "disease_id": "DOID:0070143", "name": "autosomal recessive cutis laxa type III", "description": "A cutis laxa characterized by a progeria-like appearance, ophthalmologic abnormalities, large and late-closing fontanel, joint hyperlaxity, athetoid movements, hyperreflexia, growth retardation, intellectual deficit, developmental delay, corneal clouding, and cataract.", "url": "https://disease-ontology.org/term/DOID:0070143", "evidence": [ { "id": "0070143", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070143" } ], "weight": 0.0 }, { "disease_id": "DOID:0110824", "name": "hereditary spastic paraplegia 9A", "description": "A hereditary spastic paraplegia that has_material_basis_in autosomal dominant heterozygous mutation in the ALDH18A1 gene on chromosome 10q24.", "url": "https://disease-ontology.org/term/DOID:0110824", "evidence": [ { "id": "0110824", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110824" } ], "weight": 0.0 }, { "disease_id": "DOID:0110825", "name": "hereditary spastic paraplegia 9B", "description": "A hereditary spastic paraplegia that has_material_basis_in autosomal recessive homozygous or compound heterozygous mutation in the ALDH18A1 gene on chromosome 10q24.", "url": "https://disease-ontology.org/term/DOID:0110825", "evidence": [ { "id": "0110825", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110825" } ], "weight": 0.0 }, { "disease_id": "DOID:1283", "name": "enterocele", "description": "A prolapse of female genital organ that is characterized by the descent of a peritoneal sac containing small bowel into the rectovagnial space causing a bulge in the posterior vaginal wall.", "url": "https://disease-ontology.org/term/DOID:1283", "evidence": [ { "id": "1283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1283" } ], "weight": 0.0 }, { "disease_id": "DOID:2476", "name": "hereditary spastic paraplegia", "description": "A paraplegia that is characterized by progressive stiffness and contraction (spasticity) in the lower limbs.", "url": "https://disease-ontology.org/term/DOID:2476", "evidence": [ { "id": "2476", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2476" } ], "weight": 0.0 }, { "disease_id": "DOID:83", "name": "cataract", "description": "A lens disease characterized by clouding of the lens inside the eye which leads to a decrease in vision.", "url": "https://disease-ontology.org/term/DOID:83", "evidence": [ { "id": "83", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:83" } ], "weight": 0.0 }, { "disease_id": "DOID:9252", "name": "amino acid metabolic disorder", "description": "An inherited metabolic disorder that is characterized by impaired synthesis and degradation of amino acids.", "url": "https://disease-ontology.org/term/DOID:9252", "evidence": [ { "id": "9252", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9252" } ], "weight": 0.0 } ], "biological_process": [ { "name": "citrulline biosynthetic process", "id": "GO:0019240", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019240", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AAN3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AAN3" } ], "pmid": "" }, { "name": "glutamate metabolic process", "id": "GO:0006536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006536", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AAN3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AAN3" } ], "pmid": "" }, { "name": "response to temperature stimulus", "id": "GO:0009266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009266", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AAN3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AAN3" } ], "pmid": "" }, { "name": "L-proline biosynthetic process", "id": "GO:0055129", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055129", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AAN3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AAN3" } ], "pmid": "" }, { "name": "ornithine biosynthetic process", "id": "GO:0006592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006592", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AAN3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AAN3" } ], "pmid": "" } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AAN3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AAN3" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AAN3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AAN3" } ], "pmid": "" }, { "name": "glutamate 5-kinase activity", "id": "GO:0004349", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004349", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AAN3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AAN3" } ], "pmid": "" }, { "name": "glutamate-5-semialdehyde dehydrogenase activity", "id": "GO:0004350", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004350", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AAN3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AAN3" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AAN3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AAN3" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AAN3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AAN3" } ], "pmid": "" }, { "name": "mitochondrial membrane", "id": "GO:0031966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031966", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AAN3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AAN3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6AAN3-1", "start_pos": "362", "end_pos": "362", "site_lbl": "Thr362", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 362, "start_aa": "Thr", "end_pos": 362, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr362", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6AAN3-1" }, { "uniprot_canonical_ac": "A0A8I6AAX6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AAX6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AAX6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 256, "chemical_mass": 27105.0, "gene_names": "Gapdh-ps1", "protein_name": "", "disease": [], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AAX6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AAX6" } ], "pmid": "" } ], "molecular_function": [ { "name": "NAD binding", "id": "GO:0051287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051287", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AAX6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AAX6" } ], "pmid": "" }, { "name": "glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity", "id": "GO:0004365", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004365", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AAX6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AAX6" } ], "pmid": "" } ], "biological_process": [ { "name": "glycolytic process", "id": "GO:0006096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006096", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AAX6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AAX6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AAX6-1" }, { "uniprot_canonical_ac": "A0A8I6AB90-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AB90", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AB90" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 572, "chemical_mass": 61798.0, "gene_names": "Foxn4;Foxn4", "protein_name": "", "disease": [], "molecular_function": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AB90", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AB90" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AB90", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AB90" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AB90", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AB90" } ], "pmid": "" }, { "name": "cis-regulatory region sequence-specific DNA binding", "id": "GO:0000987", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000987", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AB90", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AB90" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AB90", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AB90" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AB90", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AB90" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AB90", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AB90" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AB90", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AB90" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AB90", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AB90" } ], "pmid": "" }, { "name": "retina layer formation", "id": "GO:0010842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010842", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AB90", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AB90" } ], "pmid": "" }, { "name": "neuron fate commitment", "id": "GO:0048663", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048663", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AB90", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AB90" } ], "pmid": "" }, { "name": "ventral spinal cord interneuron fate commitment", "id": "GO:0060579", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060579", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AB90", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AB90" } ], "pmid": "" }, { "name": "ventral spinal cord interneuron differentiation", "id": "GO:0021514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021514", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AB90", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AB90" } ], "pmid": "" }, { "name": "amacrine cell differentiation", "id": "GO:0035881", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035881", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AB90", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AB90" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AB90-1" }, { "uniprot_canonical_ac": "A0A8I6AJ81-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJ81", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJ81" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 841, "chemical_mass": 94771.0, "gene_names": "Utp14a", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJ81", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJ81" } ], "pmid": "" }, { "name": "small-subunit processome", "id": "GO:0032040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032040", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJ81", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJ81" } ], "pmid": "" } ], "biological_process": [ { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AJ81", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AJ81" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AJ81-1" }, { "uniprot_canonical_ac": "A0A8I6A9R8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A9R8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A9R8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 308, "chemical_mass": 34653.0, "gene_names": "Cope;Cope", "protein_name": "Coatomer subunit epsilon", "disease": [ { "disease_id": "DOID:0112219", "name": "developmental and epileptic encephalopathy 84", "description": "A developmental and epileptic encephalopathy characterized by onset in the first months or years of life of refractory seizures, severely impaired global development, impaired intellectual development, absent speech, and inability to walk that has_material_basis_in homozygous or compound heterozygous mutation in the UGDH gene on chromosome 4p14.", "url": "https://disease-ontology.org/term/DOID:0112219", "evidence": [ { "id": "0112219", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112219" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A9R8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A9R8" } ], "pmid": "" }, { "name": "COPI-coated vesicle membrane", "id": "GO:0030663", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030663", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A9R8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A9R8" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A9R8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A9R8" } ], "pmid": "" }, { "name": "COPI-coated vesicle", "id": "GO:0030137", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030137", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A9R8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A9R8" } ], "pmid": "" }, { "name": "COPI vesicle coat", "id": "GO:0030126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030126", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A9R8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A9R8" } ], "pmid": "" } ], "biological_process": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A9R8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A9R8" } ], "pmid": "" }, { "name": "retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum", "id": "GO:0006890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006890", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A9R8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A9R8" } ], "pmid": "" }, { "name": "protein localization to axon", "id": "GO:0099612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099612", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A9R8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A9R8" } ], "pmid": "" }, { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A9R8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A9R8" } ], "pmid": "" }, { "name": "intra-Golgi vesicle-mediated transport", "id": "GO:0006891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006891", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A9R8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A9R8" } ], "pmid": "" } ], "molecular_function": [ { "name": "structural molecule activity", "id": "GO:0005198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005198", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A9R8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A9R8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6A9R8-1" }, { "uniprot_canonical_ac": "A0A8I6AL84-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AL84", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AL84" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1358, "chemical_mass": 148015.0, "gene_names": "Kank1", "protein_name": "", "disease": [ { "disease_id": "DOID:0081360", "name": "spastic quadriplegic cerebral palsy 2", "description": "A spastic quadriplegic cerebral palsy that has_material_basis_in deletion of the ANKRD15 gene (KANK1) inherited on the paternal allele.", "url": "https://disease-ontology.org/term/DOID:0081360", "evidence": [ { "id": "0081360", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081360" } ], "weight": 0.0 }, { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 }, { "disease_id": "DOID:4450", "name": "renal cell carcinoma", "description": "A renal carcinoma that has_material_basis_in the lining of the proximal convoluted renal tubule of the kidney.", "url": "https://disease-ontology.org/term/DOID:4450", "evidence": [ { "id": "4450", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4450" } ], "weight": 0.0 } ], "biological_process": [ { "name": "regulation of Rho protein signal transduction", "id": "GO:0035023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035023", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AL84", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AL84" } ], "pmid": "" }, { "name": "podocyte cell migration", "id": "GO:0090521", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090521", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AL84", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AL84" } ], "pmid": "" }, { "name": "negative regulation of actin filament polymerization", "id": "GO:0030837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030837", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AL84", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AL84" } ], "pmid": "" }, { "name": "negative regulation of insulin receptor signaling pathway", "id": "GO:0046627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046627", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AL84", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AL84" } ], "pmid": "" }, { "name": "negative regulation of ruffle assembly", "id": "GO:1900028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900028", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AL84", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AL84" } ], "pmid": "" }, { "name": "cell population proliferation", "id": "GO:0008283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008283", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AL84", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AL84" } ], "pmid": "" }, { "name": "negative regulation of cell migration", "id": "GO:0030336", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030336", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AL84", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AL84" } ], "pmid": "" }, { "name": "negative regulation of neuron projection development", "id": "GO:0010977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010977", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AL84", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AL84" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AL84", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AL84" } ], "pmid": "" }, { "name": "positive regulation of wound healing", "id": "GO:0090303", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090303", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AL84", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AL84" } ], "pmid": "" }, { "name": "positive regulation of canonical Wnt signaling pathway", "id": "GO:0090263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090263", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AL84", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AL84" } ], "pmid": "" }, { "name": "negative regulation of Rho protein signal transduction", "id": "GO:0035024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035024", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AL84", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AL84" } ], "pmid": "" }, { "name": "negative regulation of substrate adhesion-dependent cell spreading", "id": "GO:1900025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900025", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AL84", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AL84" } ], "pmid": "" }, { "name": "negative regulation of lamellipodium morphogenesis", "id": "GO:2000393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000393", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AL84", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AL84" } ], "pmid": "" }, { "name": "regulation of establishment of cell polarity", "id": "GO:2000114", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000114", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AL84", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AL84" } ], "pmid": "" }, { "name": "positive regulation of Wnt signaling pathway", "id": "GO:0030177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030177", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AL84", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AL84" } ], "pmid": "" }, { "name": "cortical microtubule organization", "id": "GO:0043622", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043622", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AL84", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AL84" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AL84", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AL84" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AL84", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AL84" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AL84", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AL84" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AL84", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AL84" } ], "pmid": "" }, { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AL84", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AL84" } ], "pmid": "" }, { "name": "ruffle membrane", "id": "GO:0032587", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032587", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AL84", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AL84" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AL84", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AL84" } ], "pmid": "" }, { "name": "beta-catenin binding", "id": "GO:0008013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008013", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AL84", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AL84" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AL84-1" }, { "uniprot_canonical_ac": "A0A8I6AIR4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AIR4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AIR4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 784, "chemical_mass": 89119.0, "gene_names": "Bank1;Bank1;LRRGT00104", "protein_name": "B-cell scaffold protein with ankyrin repeats", "disease": [ { "disease_id": "DOID:1580", "name": "diffuse scleroderma", "description": "", "url": "https://disease-ontology.org/term/DOID:1580", "evidence": [ { "id": "1580", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1580" } ], "weight": 0.0 }, { "disease_id": "DOID:418", "name": "systemic scleroderma", "description": "A scleroderma that is characterized by fibrosis (or hardening) of the skin and major organs, as well as vascular alterations, and autoantibodies.", "url": "https://disease-ontology.org/term/DOID:418", "evidence": [ { "id": "418", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:418" } ], "weight": 0.0 }, { "disease_id": "DOID:7188", "name": "autoimmune thyroiditis", "description": "An autoimmune disease of endocrine system that involves inflammation located_in thyroid gland caused by the immune system reacting against its own tissues.", "url": "https://disease-ontology.org/term/DOID:7188", "evidence": [ { "id": "7188", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7188" } ], "weight": 0.0 }, { "disease_id": "DOID:8893", "name": "psoriasis", "description": "A skin disease that is characterized by patches of thick red skin and silvery scales.", "url": "https://disease-ontology.org/term/DOID:8893", "evidence": [ { "id": "8893", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8893" } ], "weight": 0.0 }, { "disease_id": "DOID:9074", "name": "systemic lupus erythematosus", "description": "A lupus erythematosus that is an inflammation of connective tissue marked by skin rashes, joint pain and swelling, inflammation of the kidneys and inflammation of the tissue surrounding the heart.", "url": "https://disease-ontology.org/term/DOID:9074", "evidence": [ { "id": "9074", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9074" } ], "weight": 0.0 }, { "disease_id": "DOID:9744", "name": "type 1 diabetes mellitus", "description": "A diabetes mellitus that is characterized by destruction of pancreatic beta cells resulting in absent or extremely low insulin production.", "url": "https://disease-ontology.org/term/DOID:9744", "evidence": [ { "id": "9744", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9744" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "protease binding", "id": "GO:0002020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002020", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AIR4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AIR4" } ], "pmid": "" }, { "name": "signaling receptor binding", "id": "GO:0005102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005102", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AIR4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AIR4" } ], "pmid": "" }, { "name": "signaling adaptor activity", "id": "GO:0035591", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035591", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AIR4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AIR4" } ], "pmid": "" }, { "name": "phospholipase binding", "id": "GO:0043274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043274", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AIR4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AIR4" } ], "pmid": "" }, { "name": "protein tyrosine kinase binding", "id": "GO:1990782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990782", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AIR4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AIR4" } ], "pmid": "" } ], "biological_process": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AIR4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AIR4" } ], "pmid": "" }, { "name": "positive regulation of MAPK cascade", "id": "GO:0043410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043410", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AIR4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AIR4" } ], "pmid": "" }, { "name": "negative regulation of interleukin-6 production", "id": "GO:0032715", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032715", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AIR4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AIR4" } ], "pmid": "" }, { "name": "B cell activation", "id": "GO:0042113", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042113", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AIR4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AIR4" } ], "pmid": "" }, { "name": "response to bacterium", "id": "GO:0009617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009617", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AIR4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AIR4" } ], "pmid": "" }, { "name": "positive regulation of peptidyl-tyrosine phosphorylation", "id": "GO:0050731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050731", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AIR4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AIR4" } ], "pmid": "" }, { "name": "negative regulation of translational initiation", "id": "GO:0045947", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045947", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AIR4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AIR4" } ], "pmid": "" }, { "name": "negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction", "id": "GO:0051898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051898", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AIR4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AIR4" } ], "pmid": "" }, { "name": "negative regulation of B cell activation", "id": "GO:0050869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050869", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AIR4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AIR4" } ], "pmid": "" } ], "cellular_component": [ { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AIR4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AIR4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6AIR4-1", "start_pos": "614", "end_pos": "614", "site_lbl": "Thr614", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 614, "start_aa": "Thr", "end_pos": 614, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr614", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6AIR4-1" }, { "uniprot_canonical_ac": "F7EZ61-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F7EZ61", "url": "https://www.uniprot.org/uniprotkb/F7EZ61" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 475, "chemical_mass": 53685.0, "gene_names": "Btbd10;Btbd10;RGD1306301", "protein_name": "", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F7EZ61", "url": "https://www.uniprot.org/uniprotkb/F7EZ61" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F7EZ61", "url": "https://www.uniprot.org/uniprotkb/F7EZ61" } ], "pmid": "" }, { "name": "fibrillar center", "id": "GO:0001650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001650", "evidence": [ { "database": "UniProtKB", "id": "F7EZ61", "url": "https://www.uniprot.org/uniprotkb/F7EZ61" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction", "id": "GO:0051897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051897", "evidence": [ { "database": "UniProtKB", "id": "F7EZ61", "url": "https://www.uniprot.org/uniprotkb/F7EZ61" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "F7EZ61-1" }, { "uniprot_canonical_ac": "A0A8I6G1L6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G1L6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G1L6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 3011, "chemical_mass": 338388.0, "gene_names": "Fry;Fry;RGD1307034", "protein_name": "", "disease": [ { "disease_id": "DOID:0050888", "name": "syndromic intellectual disability", "description": "An intellectual disability that is characterized by the presence of associated medical and behavioral sign and symptoms.", "url": "https://disease-ontology.org/term/DOID:0050888", "evidence": [ { "id": "0050888", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050888" } ], "weight": 0.0 } ], "biological_process": [ { "name": "cell morphogenesis", "id": "GO:0000902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000902", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G1L6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G1L6" } ], "pmid": "" }, { "name": "negative regulation of tubulin deacetylation", "id": "GO:1904428", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904428", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G1L6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G1L6" } ], "pmid": "" }, { "name": "neuron projection development", "id": "GO:0031175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031175", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G1L6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G1L6" } ], "pmid": "" } ], "molecular_function": [ { "name": "enzyme inhibitor activity", "id": "GO:0004857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004857", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G1L6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G1L6" } ], "pmid": "" } ], "cellular_component": [ { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G1L6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G1L6" } ], "pmid": "" }, { "name": "site of polarized growth", "id": "GO:0030427", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030427", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G1L6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G1L6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6G1L6-1", "start_pos": "1964", "end_pos": "1964", "site_lbl": "Thr1964", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1964, "start_aa": "Thr", "end_pos": 1964, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1964", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I6G1L6-1", "start_pos": "2560", "end_pos": "2560", "site_lbl": "Thr2560", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2560, "start_aa": "Thr", "end_pos": 2560, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2560", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6G1L6-1" }, { "uniprot_canonical_ac": "A0A8I6AG83-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AG83", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AG83" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 303, "chemical_mass": 33213.0, "gene_names": "Rpp30", "protein_name": "", "disease": [], "cellular_component": [ { "name": "multimeric ribonuclease P complex", "id": "GO:0030681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030681", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AG83", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AG83" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AG83", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AG83" } ], "pmid": "" }, { "name": "ribonuclease MRP complex", "id": "GO:0000172", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000172", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AG83", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AG83" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AG83", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AG83" } ], "pmid": "" }, { "name": "nucleolar ribonuclease P complex", "id": "GO:0005655", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005655", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AG83", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AG83" } ], "pmid": "" } ], "molecular_function": [ { "name": "ribonuclease P activity", "id": "GO:0004526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004526", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AG83", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AG83" } ], "pmid": "" }, { "name": "ribonuclease P RNA binding", "id": "GO:0033204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033204", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AG83", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AG83" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AG83", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AG83" } ], "pmid": "" } ], "biological_process": [ { "name": "tRNA 5'-leader removal", "id": "GO:0001682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001682", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AG83", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AG83" } ], "pmid": "" }, { "name": "tRNA processing", "id": "GO:0008033", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008033", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AG83", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AG83" } ], "pmid": "" }, { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AG83", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AG83" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AG83-1" }, { "uniprot_canonical_ac": "A0A8I6AKZ9-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AKZ9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AKZ9" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 376, "chemical_mass": 42281.0, "gene_names": "Actr1b;Actr1b", "protein_name": "Beta-centractin", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AKZ9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AKZ9" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AKZ9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AKZ9" } ], "pmid": "" }, { "name": "dynactin complex", "id": "GO:0005869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005869", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AKZ9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AKZ9" } ], "pmid": "" } ], "molecular_function": [ { "name": "structural constituent of cytoskeleton", "id": "GO:0005200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005200", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AKZ9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AKZ9" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AKZ9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AKZ9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AKZ9-1" }, { "uniprot_canonical_ac": "A0A8I6G3L4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3L4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3L4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 579, "chemical_mass": 65607.0, "gene_names": "Mcoln1", "protein_name": "", "disease": [ { "disease_id": "DOID:0060450", "name": "Lisch epithelial corneal dystrophy", "description": "An epithelial and subepithelial dystrophy that is characterized by bilateral or unilateral, gray, band-shaped, and feathery opacities that sometimes appeared in whorled patterns and that has_material_basis_in the MCOLN1 gene on Chr. 19.", "url": "https://disease-ontology.org/term/DOID:0060450", "evidence": [ { "id": "0060450", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060450" } ], "weight": 0.0 }, { "disease_id": "DOID:0080490", "name": "mucolipidosis type IV", "description": "A mucolipidosis that is characterized by delayed development and vision impairment that worsens over time.", "url": "https://disease-ontology.org/term/DOID:0080490", "evidence": [ { "id": "0080490", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080490" } ], "weight": 0.0 }, { "disease_id": "DOID:3343", "name": "glycoproteinosis", "description": "A mucolipidosis that is characterized by a deficiency of the enzyme alpha-N -acetyl neuraminidase (sialidase).", "url": "https://disease-ontology.org/term/DOID:3343", "evidence": [ { "id": "3343", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3343" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3L4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3L4" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3L4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3L4" } ], "pmid": "" }, { "name": "intracellular vesicle", "id": "GO:0097708", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097708", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3L4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3L4" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3L4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3L4" } ], "pmid": "" }, { "name": "receptor complex", "id": "GO:0043235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043235", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3L4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3L4" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3L4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3L4" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3L4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3L4" } ], "pmid": "" }, { "name": "late endosome", "id": "GO:0005770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005770", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3L4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3L4" } ], "pmid": "" } ], "molecular_function": [ { "name": "monoatomic cation channel activity", "id": "GO:0005261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005261", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3L4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3L4" } ], "pmid": "" }, { "name": "NAADP-sensitive calcium-release channel activity", "id": "GO:0072345", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072345", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3L4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3L4" } ], "pmid": "" }, { "name": "calcium channel activity", "id": "GO:0005262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005262", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3L4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3L4" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3L4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3L4" } ], "pmid": "" }, { "name": "potassium channel activity", "id": "GO:0005267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005267", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3L4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3L4" } ], "pmid": "" }, { "name": "monoatomic anion channel activity", "id": "GO:0005253", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005253", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3L4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3L4" } ], "pmid": "" }, { "name": "sodium channel activity", "id": "GO:0005272", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005272", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3L4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3L4" } ], "pmid": "" }, { "name": "iron ion transmembrane transporter activity", "id": "GO:0005381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005381", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3L4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3L4" } ], "pmid": "" }, { "name": "ligand-gated calcium channel activity", "id": "GO:0099604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099604", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3L4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3L4" } ], "pmid": "" }, { "name": "intracellularly phosphatidylinositol-3,5-bisphosphate-gated monatomic cation channel activity", "id": "GO:0097682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097682", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3L4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3L4" } ], "pmid": "" } ], "biological_process": [ { "name": "autophagosome maturation", "id": "GO:0097352", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097352", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3L4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3L4" } ], "pmid": "" }, { "name": "phagosome maturation", "id": "GO:0090382", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090382", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3L4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3L4" } ], "pmid": "" }, { "name": "iron ion transmembrane transport", "id": "GO:0034755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034755", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3L4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3L4" } ], "pmid": "" }, { "name": "protein homotetramerization", "id": "GO:0051289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051289", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3L4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3L4" } ], "pmid": "" }, { "name": "cellular response to calcium ion", "id": "GO:0071277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071277", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3L4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3L4" } ], "pmid": "" }, { "name": "monoatomic cation transmembrane transport", "id": "GO:0098655", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098655", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3L4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3L4" } ], "pmid": "" }, { "name": "release of sequestered calcium ion into cytosol", "id": "GO:0051209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051209", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3L4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3L4" } ], "pmid": "" }, { "name": "calcium ion transmembrane transport", "id": "GO:0070588", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070588", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3L4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3L4" } ], "pmid": "" }, { "name": "cellular response to pH", "id": "GO:0071467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071467", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3L4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3L4" } ], "pmid": "" }, { "name": "intracellular zinc ion homeostasis", "id": "GO:0006882", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006882", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3L4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3L4" } ], "pmid": "" }, { "name": "calcium ion export", "id": "GO:1901660", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901660", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3L4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3L4" } ], "pmid": "" }, { "name": "positive regulation of lysosome organization", "id": "GO:1905673", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905673", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G3L4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G3L4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6G3L4-1" }, { "uniprot_canonical_ac": "A0A8I6G358-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G358", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G358" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 740, "chemical_mass": 84256.0, "gene_names": "Fchsd2;Fchsd2", "protein_name": "F-BAR and double SH3 domains protein 2", "disease": [], "molecular_function": [ { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G358", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G358" } ], "pmid": "" }, { "name": "phosphatidylinositol-3,4,5-trisphosphate binding", "id": "GO:0005547", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005547", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G358", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G358" } ], "pmid": "" }, { "name": "phosphatidylinositol-3,4-bisphosphate binding", "id": "GO:0043325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043325", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G358", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G358" } ], "pmid": "" } ], "cellular_component": [ { "name": "cell projection", "id": "GO:0042995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042995", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G358", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G358" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G358", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G358" } ], "pmid": "" }, { "name": "clathrin-coated pit", "id": "GO:0005905", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005905", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G358", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G358" } ], "pmid": "" }, { "name": "neuromuscular junction", "id": "GO:0031594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031594", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G358", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G358" } ], "pmid": "" }, { "name": "recycling endosome", "id": "GO:0055037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055037", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G358", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G358" } ], "pmid": "" }, { "name": "stereocilium shaft", "id": "GO:0120043", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120043", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G358", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G358" } ], "pmid": "" }, { "name": "anchoring junction", "id": "GO:0070161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070161", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G358", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G358" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G358", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G358" } ], "pmid": "" }, { "name": "stereocilium", "id": "GO:0032420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032420", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G358", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G358" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of actin filament polymerization", "id": "GO:0030838", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030838", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G358", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G358" } ], "pmid": "" }, { "name": "neuromuscular synaptic transmission", "id": "GO:0007274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007274", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G358", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G358" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G358", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G358" } ], "pmid": "" }, { "name": "membrane organization", "id": "GO:0061024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061024", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G358", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G358" } ], "pmid": "" }, { "name": "positive regulation of Arp2/3 complex-mediated actin nucleation", "id": "GO:2000601", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000601", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G358", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G358" } ], "pmid": "" }, { "name": "clathrin-dependent endocytosis", "id": "GO:0072583", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072583", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G358", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G358" } ], "pmid": "" }, { "name": "regulation of actin filament polymerization", "id": "GO:0030833", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030833", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G358", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G358" } ], "pmid": "" }, { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G358", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G358" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6G358-1", "start_pos": "722", "end_pos": "722", "site_lbl": "Thr722", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 722, "start_aa": "Thr", "end_pos": 722, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr722", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6G358-1" }, { "uniprot_canonical_ac": "A0A8I6GM39-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GM39", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GM39" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1594, "chemical_mass": 177642.0, "gene_names": "Topbp1", "protein_name": "DNA topoisomerase 2-binding protein 1", "disease": [], "cellular_component": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GM39", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GM39" } ], "pmid": "" }, { "name": "BRCA1-B complex", "id": "GO:0070532", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070532", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GM39", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GM39" } ], "pmid": "" }, { "name": "condensed nuclear chromosome", "id": "GO:0000794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000794", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GM39", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GM39" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GM39", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GM39" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GM39", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GM39" } ], "pmid": "" }, { "name": "male germ cell nucleus", "id": "GO:0001673", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001673", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GM39", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GM39" } ], "pmid": "" }, { "name": "PML body", "id": "GO:0016605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016605", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GM39", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GM39" } ], "pmid": "" }, { "name": "site of double-strand break", "id": "GO:0035861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035861", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GM39", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GM39" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GM39", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GM39" } ], "pmid": "" }, { "name": "site of DNA damage", "id": "GO:0090734", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090734", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GM39", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GM39" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GM39", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GM39" } ], "pmid": "" }, { "name": "mitotic G2 DNA damage checkpoint signaling", "id": "GO:0007095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007095", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GM39", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GM39" } ], "pmid": "" }, { "name": "DNA replication initiation", "id": "GO:0006270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GM39", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GM39" } ], "pmid": "" }, { "name": "mitotic DNA replication checkpoint signaling", "id": "GO:0033314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033314", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GM39", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GM39" } ], "pmid": "" }, { "name": "protein localization to site of double-strand break", "id": "GO:1990166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990166", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GM39", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GM39" } ], "pmid": "" }, { "name": "DNA replication checkpoint signaling", "id": "GO:0000076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000076", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GM39", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GM39" } ], "pmid": "" }, { "name": "double-strand break repair via classical nonhomologous end joining", "id": "GO:0097680", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097680", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GM39", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GM39" } ], "pmid": "" }, { "name": "double-strand break repair via alternative nonhomologous end joining", "id": "GO:0097681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097681", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GM39", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GM39" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GM39", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GM39" } ], "pmid": "" }, { "name": "response to ionizing radiation", "id": "GO:0010212", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010212", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GM39", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GM39" } ], "pmid": "" }, { "name": "double-strand break repair via homologous recombination", "id": "GO:0000724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000724", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GM39", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GM39" } ], "pmid": "" }, { "name": "DNA damage checkpoint signaling", "id": "GO:0000077", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000077", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GM39", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GM39" } ], "pmid": "" }, { "name": "chromosome organization", "id": "GO:0051276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051276", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GM39", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GM39" } ], "pmid": "" }, { "name": "broken chromosome clustering", "id": "GO:0141112", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141112", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GM39", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GM39" } ], "pmid": "" } ], "molecular_function": [ { "name": "chromatin-protein adaptor activity", "id": "GO:0140463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140463", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GM39", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GM39" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GM39", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GM39" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activator activity", "id": "GO:0043539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043539", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GM39", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GM39" } ], "pmid": "" }, { "name": "phosphorylation-dependent protein binding", "id": "GO:0140031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140031", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GM39", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GM39" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6GM39-1" }, { "uniprot_canonical_ac": "A0A8I6AIZ7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AIZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AIZ7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 409, "chemical_mass": 46227.0, "gene_names": "Deptor;Depdc6;Deptor;RGD1561030", "protein_name": "DEP domain-containing mTOR-interacting protein", "disease": [], "biological_process": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AIZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AIZ7" } ], "pmid": "" }, { "name": "negative regulation of TOR signaling", "id": "GO:0032007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032007", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AIZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AIZ7" } ], "pmid": "" }, { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AIZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AIZ7" } ], "pmid": "" }, { "name": "negative regulation of protein kinase activity", "id": "GO:0006469", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006469", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AIZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AIZ7" } ], "pmid": "" }, { "name": "positive regulation of autophagy", "id": "GO:0010508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010508", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AIZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AIZ7" } ], "pmid": "" }, { "name": "regulation of extrinsic apoptotic signaling pathway", "id": "GO:2001236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001236", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AIZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AIZ7" } ], "pmid": "" }, { "name": "negative regulation of cell size", "id": "GO:0045792", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045792", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AIZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AIZ7" } ], "pmid": "" }, { "name": "negative regulation of TORC1 signaling", "id": "GO:1904262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904262", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AIZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AIZ7" } ], "pmid": "" }, { "name": "negative regulation of TORC2 signaling", "id": "GO:1903940", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903940", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AIZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AIZ7" } ], "pmid": "" } ], "molecular_function": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AIZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AIZ7" } ], "pmid": "" }, { "name": "protein kinase inhibitor activity", "id": "GO:0004860", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004860", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AIZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AIZ7" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AIZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AIZ7" } ], "pmid": "" }, { "name": "phosphatidic acid binding", "id": "GO:0070300", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070300", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AIZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AIZ7" } ], "pmid": "" }, { "name": "protein serine/threonine kinase inhibitor activity", "id": "GO:0030291", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030291", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AIZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AIZ7" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AIZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AIZ7" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AIZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AIZ7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AIZ7-1" }, { "uniprot_canonical_ac": "A0A8I5ZX76-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZX76", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZX76" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 218, "chemical_mass": 25115.0, "gene_names": "Eif3k;EIF3K;EIF3S12;Eif3k;Eif3s12;PLAC-24", "protein_name": "Eukaryotic translation initiation factor 3 subunit K", "disease": [], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZX76", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZX76" } ], "pmid": "" }, { "name": "ribosome binding", "id": "GO:0043022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043022", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZX76", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZX76" } ], "pmid": "" }, { "name": "translation initiation factor activity", "id": "GO:0003743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003743", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZX76", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZX76" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZX76", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZX76" } ], "pmid": "" }, { "name": "eukaryotic 43S preinitiation complex", "id": "GO:0016282", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016282", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZX76", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZX76" } ], "pmid": "" }, { "name": "eukaryotic 48S preinitiation complex", "id": "GO:0033290", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033290", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZX76", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZX76" } ], "pmid": "" }, { "name": "eukaryotic translation initiation factor 3 complex", "id": "GO:0005852", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005852", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZX76", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZX76" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZX76", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZX76" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of translational initiation", "id": "GO:0006446", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006446", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZX76", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZX76" } ], "pmid": "" }, { "name": "formation of cytoplasmic translation initiation complex", "id": "GO:0001732", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001732", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZX76", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZX76" } ], "pmid": "" }, { "name": "translational initiation", "id": "GO:0006413", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006413", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZX76", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZX76" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZX76-1" }, { "uniprot_canonical_ac": "A0A8I6AF72-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AF72", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AF72" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1050, "chemical_mass": 117883.0, "gene_names": "Mecom", "protein_name": "", "disease": [ { "disease_id": "DOID:0070004", "name": "myeloid neoplasm", "description": "A bone marrow cancer that is formed of any one of the bone marrow cells belonging to the granulocytic (neutrophil, eosinophil, basophil), monocytic/macrophage, erythroid, megakaryocytic and mast cell lineages.", "url": "https://disease-ontology.org/term/DOID:0070004", "evidence": [ { "id": "0070004", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070004" } ], "weight": 0.0 }, { "disease_id": "DOID:10754", "name": "otitis media", "description": "A otitis which involves inflammation of the middle ear.", "url": "https://disease-ontology.org/term/DOID:10754", "evidence": [ { "id": "10754", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10754" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AF72", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AF72" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AF72", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AF72" } ], "pmid": "" }, { "name": "histone deacetylase complex", "id": "GO:0000118", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000118", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AF72", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AF72" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AF72", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AF72" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AF72", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AF72" } ], "pmid": "" }, { "name": "maintenance of cell number", "id": "GO:0098727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098727", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AF72", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AF72" } ], "pmid": "" }, { "name": "in utero embryonic development", "id": "GO:0001701", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001701", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AF72", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AF72" } ], "pmid": "" }, { "name": "inflammatory response", "id": "GO:0006954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006954", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AF72", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AF72" } ], "pmid": "" }, { "name": "forebrain development", "id": "GO:0030900", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030900", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AF72", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AF72" } ], "pmid": "" }, { "name": "regulation of cell population proliferation", "id": "GO:0042127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042127", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AF72", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AF72" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AF72", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AF72" } ], "pmid": "" }, { "name": "response to bacterium", "id": "GO:0009617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009617", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AF72", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AF72" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AF72", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AF72" } ], "pmid": "" }, { "name": "post-embryonic development", "id": "GO:0009791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009791", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AF72", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AF72" } ], "pmid": "" }, { "name": "embryonic forelimb morphogenesis", "id": "GO:0035115", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035115", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AF72", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AF72" } ], "pmid": "" }, { "name": "negative regulation of programmed cell death", "id": "GO:0043069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043069", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AF72", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AF72" } ], "pmid": "" }, { "name": "embryonic hindlimb morphogenesis", "id": "GO:0035116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035116", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AF72", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AF72" } ], "pmid": "" }, { "name": "negative regulation of JNK cascade", "id": "GO:0046329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046329", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AF72", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AF72" } ], "pmid": "" }, { "name": "neutrophil homeostasis", "id": "GO:0001780", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001780", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AF72", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AF72" } ], "pmid": "" }, { "name": "protein maturation", "id": "GO:0051604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051604", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AF72", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AF72" } ], "pmid": "" }, { "name": "hematopoietic stem cell proliferation", "id": "GO:0071425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071425", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AF72", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AF72" } ], "pmid": "" }, { "name": "positive regulation of brown fat cell differentiation", "id": "GO:0090336", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090336", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AF72", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AF72" } ], "pmid": "" }, { "name": "ureter morphogenesis", "id": "GO:0072197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072197", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AF72", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AF72" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AF72", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AF72" } ], "pmid": "" }, { "name": "pericardium development", "id": "GO:0060039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060039", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AF72", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AF72" } ], "pmid": "" }, { "name": "heterochromatin organization", "id": "GO:0070828", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070828", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AF72", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AF72" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AF72", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AF72" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AF72", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AF72" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AF72", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AF72" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AF72", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AF72" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AF72", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AF72" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AF72", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AF72" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AF72", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AF72" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AF72", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AF72" } ], "pmid": "" }, { "name": "histone H3K9 methyltransferase activity", "id": "GO:0046974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046974", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AF72", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AF72" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AF72-1" }, { "uniprot_canonical_ac": "A0A8I6ATN1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATN1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATN1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 835, "chemical_mass": 91147.0, "gene_names": "Bcl11a;Bcl11a", "protein_name": "", "disease": [ { "disease_id": "DOID:0060038", "name": "specific developmental disorder", "description": "A developmental disorder of mental health that categorizes specific learning disabilities and developmental disorders affecting coordination.", "url": "https://disease-ontology.org/term/DOID:0060038", "evidence": [ { "id": "0060038", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060038" } ], "weight": 0.0 }, { "disease_id": "DOID:0060041", "name": "autism spectrum disorder", "description": "A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior.", "url": "https://disease-ontology.org/term/DOID:0060041", "evidence": [ { "id": "0060041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060041" } ], "weight": 0.0 }, { "disease_id": "DOID:10923", "name": "sickle cell anemia", "description": "A sickle cell disease that is characterized by the replacement of both of the beta-globin subunits in hemoglobin with hemoglobin S, resulting in a low number of red blood cells, repeated infections, and periodic episodes of pain.", "url": "https://disease-ontology.org/term/DOID:10923", "evidence": [ { "id": "10923", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10923" } ], "weight": 0.0 }, { "disease_id": "DOID:12241", "name": "beta thalassemia", "description": "A thalassemia characterized by the reduced or absent synthesis of the beta globin chains of hemoglobin.", "url": "https://disease-ontology.org/term/DOID:12241", "evidence": [ { "id": "12241", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12241" } ], "weight": 0.0 }, { "disease_id": "DOID:1289", "name": "neurodegenerative disease", "description": "A central nervous system disease that results in the progressive deterioration of function or structure of neurons.", "url": "https://disease-ontology.org/term/DOID:1289", "evidence": [ { "id": "1289", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1289" } ], "weight": 0.0 }, { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 }, { "disease_id": "DOID:5419", "name": "schizophrenia", "description": "A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness.", "url": "https://disease-ontology.org/term/DOID:5419", "evidence": [ { "id": "5419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5419" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 } ], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATN1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATN1" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATN1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATN1" } ], "pmid": "" }, { "name": "positive regulation of gene expression", "id": "GO:0010628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010628", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATN1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATN1" } ], "pmid": "" }, { "name": "negative regulation of gene expression", "id": "GO:0010629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010629", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATN1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATN1" } ], "pmid": "" }, { "name": "positive regulation of neuron projection development", "id": "GO:0010976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010976", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATN1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATN1" } ], "pmid": "" }, { "name": "protein sumoylation", "id": "GO:0016925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016925", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATN1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATN1" } ], "pmid": "" }, { "name": "negative regulation of neuron projection development", "id": "GO:0010977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010977", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATN1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATN1" } ], "pmid": "" }, { "name": "B cell differentiation", "id": "GO:0030183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030183", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATN1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATN1" } ], "pmid": "" }, { "name": "negative regulation of dendrite development", "id": "GO:2000171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000171", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATN1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATN1" } ], "pmid": "" }, { "name": "T cell differentiation", "id": "GO:0030217", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030217", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATN1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATN1" } ], "pmid": "" }, { "name": "positive regulation of collateral sprouting", "id": "GO:0048672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048672", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATN1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATN1" } ], "pmid": "" }, { "name": "cellular response to L-glutamate", "id": "GO:1905232", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905232", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATN1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATN1" } ], "pmid": "" }, { "name": "negative regulation of collateral sprouting", "id": "GO:0048671", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048671", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATN1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATN1" } ], "pmid": "" }, { "name": "regulation of dendrite development", "id": "GO:0050773", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050773", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATN1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATN1" } ], "pmid": "" }, { "name": "negative regulation of dendrite extension", "id": "GO:1903860", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903860", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATN1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATN1" } ], "pmid": "" }, { "name": "negative regulation of neuron remodeling", "id": "GO:1904800", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904800", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATN1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATN1" } ], "pmid": "" }, { "name": "negative regulation of branching morphogenesis of a nerve", "id": "GO:2000173", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000173", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATN1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATN1" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATN1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATN1" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATN1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATN1" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATN1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATN1" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATN1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATN1" } ], "pmid": "" }, { "name": "SWI/SNF complex", "id": "GO:0016514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016514", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATN1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATN1" } ], "pmid": "" }, { "name": "postsynapse", "id": "GO:0098794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098794", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATN1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATN1" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATN1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATN1" } ], "pmid": "" }, { "name": "paraspeckles", "id": "GO:0042382", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042382", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATN1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATN1" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATN1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATN1" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATN1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATN1" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATN1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATN1" } ], "pmid": "" }, { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATN1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATN1" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATN1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATN1" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATN1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATN1" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATN1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATN1" } ], "pmid": "" }, { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATN1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATN1" } ], "pmid": "" }, { "name": "transcription regulatory region nucleic acid binding", "id": "GO:0001067", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001067", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATN1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATN1" } ], "pmid": "" }, { "name": "DNA-binding transcription factor binding", "id": "GO:0140297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140297", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATN1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATN1" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATN1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATN1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6ATN1-1" }, { "uniprot_canonical_ac": "A0A8I6ATQ4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATQ4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 479, "chemical_mass": 52949.0, "gene_names": "Pax3", "protein_name": "", "disease": [ { "disease_id": "DOID:0080074", "name": "neural tube defect", "description": "A physical disorder characterized by incomplete closure of the neural tube.", "url": "https://disease-ontology.org/term/DOID:0080074", "evidence": [ { "id": "0080074", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080074" } ], "weight": 0.0 }, { "disease_id": "DOID:0110948", "name": "Waardenburg syndrome type 1", "description": "A Waardenburg syndrome characterized by autosomal dominant inheritance of congenital deafness, pigmentation anomalies of eyes, hair, and skin,and dystopia canthorum that has_material_basis_in heterozygous mutation in the PAX3 gene on chromosome 2q36.", "url": "https://disease-ontology.org/term/DOID:0110948", "evidence": [ { "id": "0110948", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110948" } ], "weight": 0.0 }, { "disease_id": "DOID:0110949", "name": "Waardenburg syndrome type 3", "description": "A Waardenburg syndrome characterized by upper limb anomalies, congenital hearing loss, dystopia canthorum and pigmentation anomalies of eyes, hair, and skin that has_material_basis_in heterozygous or homozygous mutation in the PAX3 gene on chromosome 2q36.", "url": "https://disease-ontology.org/term/DOID:0110949", "evidence": [ { "id": "0110949", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110949" } ], "weight": 0.0 }, { "disease_id": "DOID:0111336", "name": "craniofacial-deafness-hand syndrome", "description": "A syndrome characterized by a flat facial profile, hypertelorism, a hypoplastic nose with slitlike nares, and sensorineural hearing loss that has_material_basis_in heterozygous mutation in the PAX3 gene on chromosome 2q36.1.", "url": "https://disease-ontology.org/term/DOID:0111336", "evidence": [ { "id": "0111336", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111336" } ], "weight": 0.0 }, { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:4051", "name": "alveolar rhabdomyosarcoma", "description": "", "url": "https://disease-ontology.org/term/DOID:4051", "evidence": [ { "id": "4051", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4051" } ], "weight": 0.0 }, { "disease_id": "DOID:9258", "name": "Waardenburg syndrome", "description": "A syndrome characterized by varying degrees of deafness, minor defects in structures arising from the neural crest and pigmentation anomalies of the hair, the skin and/or the iris of both eyes.", "url": "https://disease-ontology.org/term/DOID:9258", "evidence": [ { "id": "9258", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9258" } ], "weight": 0.0 } ], "biological_process": [ { "name": "skeletal muscle organ development", "id": "GO:0060538", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060538", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATQ4" } ], "pmid": "" }, { "name": "mammary gland specification", "id": "GO:0060594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060594", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATQ4" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATQ4" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATQ4" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATQ4" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATQ4" } ], "pmid": "" }, { "name": "heart development", "id": "GO:0007507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007507", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATQ4" } ], "pmid": "" }, { "name": "cell population proliferation", "id": "GO:0008283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008283", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATQ4" } ], "pmid": "" }, { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATQ4" } ], "pmid": "" }, { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATQ4" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATQ4" } ], "pmid": "" }, { "name": "muscle organ development", "id": "GO:0007517", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007517", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATQ4" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATQ4" } ], "pmid": "" }, { "name": "neural crest cell migration", "id": "GO:0001755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001755", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATQ4" } ], "pmid": "" }, { "name": "neural tube closure", "id": "GO:0001843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001843", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATQ4" } ], "pmid": "" }, { "name": "neural tube development", "id": "GO:0021915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021915", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATQ4" } ], "pmid": "" }, { "name": "gliogenesis", "id": "GO:0042063", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042063", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATQ4" } ], "pmid": "" }, { "name": "spinal cord association neuron differentiation", "id": "GO:0021527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021527", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATQ4" } ], "pmid": "" }, { "name": "neuron fate commitment", "id": "GO:0048663", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048663", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATQ4" } ], "pmid": "" }, { "name": "developmental pigmentation", "id": "GO:0048066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048066", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATQ4" } ], "pmid": "" }, { "name": "regulation of somitogenesis", "id": "GO:0014807", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014807", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATQ4" } ], "pmid": "" }, { "name": "tissue morphogenesis", "id": "GO:0048729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048729", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATQ4" } ], "pmid": "" }, { "name": "animal organ development", "id": "GO:0048513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048513", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATQ4" } ], "pmid": "" }, { "name": "anatomical structure morphogenesis", "id": "GO:0009653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009653", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATQ4" } ], "pmid": "" } ], "molecular_function": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATQ4" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATQ4" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATQ4" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATQ4" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATQ4" } ], "pmid": "" }, { "name": "transcription coregulator binding", "id": "GO:0001221", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001221", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATQ4" } ], "pmid": "" }, { "name": "sequence-specific double-stranded DNA binding", "id": "GO:1990837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990837", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATQ4" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATQ4" } ], "pmid": "" }, { "name": "HMG box domain binding", "id": "GO:0071837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071837", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATQ4" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATQ4" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATQ4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6ATQ4-1" }, { "uniprot_canonical_ac": "A0A8I6AV56-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AV56", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AV56" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 582, "chemical_mass": 64847.0, "gene_names": "Nprl3;Mare;Nprl3;RGD1308665", "protein_name": "GATOR complex protein NPRL3", "disease": [ { "disease_id": "DOID:0081423", "name": "familial focal epilepsy with variable foci 3", "description": "A familial focal epilepsy with variable foci that has_material_basis_in heterozygous mutation in the NPRL3 gene on chromosome 16p13.", "url": "https://disease-ontology.org/term/DOID:0081423", "evidence": [ { "id": "0081423", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081423" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AV56", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AV56" } ], "pmid": "" }, { "name": "GATOR1 complex", "id": "GO:1990130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990130", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AV56", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AV56" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AV56", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AV56" } ], "pmid": "" } ], "biological_process": [ { "name": "cardiac muscle tissue development", "id": "GO:0048738", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048738", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AV56", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AV56" } ], "pmid": "" }, { "name": "ventricular septum development", "id": "GO:0003281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003281", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AV56", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AV56" } ], "pmid": "" }, { "name": "roof of mouth development", "id": "GO:0060021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060021", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AV56", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AV56" } ], "pmid": "" }, { "name": "aorta morphogenesis", "id": "GO:0035909", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035909", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AV56", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AV56" } ], "pmid": "" }, { "name": "cellular response to amino acid starvation", "id": "GO:0034198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034198", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AV56", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AV56" } ], "pmid": "" }, { "name": "negative regulation of TORC1 signaling", "id": "GO:1904262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904262", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AV56", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AV56" } ], "pmid": "" }, { "name": "positive regulation of autophagy", "id": "GO:0010508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010508", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AV56", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AV56" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AV56-1" }, { "uniprot_canonical_ac": "A0A8I6GG17-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GG17", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GG17" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 87, "chemical_mass": 9818.0, "gene_names": "Spata33", "protein_name": "", "disease": [], "cellular_component": [ { "name": "sperm mitochondrial sheath", "id": "GO:0097226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097226", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GG17", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GG17" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GG17", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GG17" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GG17", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GG17" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GG17", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GG17" } ], "pmid": "" }, { "name": "sperm midpiece", "id": "GO:0097225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097225", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GG17", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GG17" } ], "pmid": "" } ], "biological_process": [ { "name": "fertilization", "id": "GO:0009566", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009566", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GG17", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GG17" } ], "pmid": "" }, { "name": "flagellated sperm motility", "id": "GO:0030317", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030317", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GG17", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GG17" } ], "pmid": "" }, { "name": "intracellular protein localization", "id": "GO:0008104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008104", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GG17", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GG17" } ], "pmid": "" }, { "name": "mitophagy", "id": "GO:0000423", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000423", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GG17", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GG17" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-containing complex binding", "id": "GO:0044877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044877", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GG17", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GG17" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6GG17-1" }, { "uniprot_canonical_ac": "A0A8I6AEG5-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEG5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEG5" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 623, "chemical_mass": 68725.0, "gene_names": "Pja1;Pja1", "protein_name": "RING-type E3 ubiquitin transferase", "disease": [], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEG5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEG5" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEG5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEG5" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEG5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEG5" } ], "pmid": "" } ], "biological_process": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEG5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEG5" } ], "pmid": "" }, { "name": "protein catabolic process", "id": "GO:0030163", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030163", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEG5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEG5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AEG5-1" }, { "uniprot_canonical_ac": "A0A8I6GFL9-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GFL9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GFL9" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1000, "chemical_mass": 110266.0, "gene_names": "Lrp8;Lrp8", "protein_name": "Low-density lipoprotein receptor-related protein 8", "disease": [ { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:1307", "name": "dementia", "description": "A cognitive disorder resulting from a loss of brain function affecting memory, thinking, language, judgement and behavior.", "url": "https://disease-ontology.org/term/DOID:1307", "evidence": [ { "id": "1307", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1307" } ], "weight": 0.0 }, { "disease_id": "DOID:3393", "name": "coronary artery disease", "description": "An artery disease that is characterized by plaque building up along the inner walls of the arteries of the heart resulting in a narrowing of the arteries and a reduced blood supply to the cardiac muscles.", "url": "https://disease-ontology.org/term/DOID:3393", "evidence": [ { "id": "3393", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3393" } ], "weight": 0.0 }, { "disease_id": "DOID:5419", "name": "schizophrenia", "description": "A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness.", "url": "https://disease-ontology.org/term/DOID:5419", "evidence": [ { "id": "5419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5419" } ], "weight": 0.0 }, { "disease_id": "DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia.", "url": "https://disease-ontology.org/term/DOID:5844", "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GFL9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GFL9" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GFL9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GFL9" } ], "pmid": "" }, { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GFL9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GFL9" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GFL9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GFL9" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GFL9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GFL9" } ], "pmid": "" }, { "name": "receptor complex", "id": "GO:0043235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043235", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GFL9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GFL9" } ], "pmid": "" }, { "name": "caveola", "id": "GO:0005901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005901", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GFL9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GFL9" } ], "pmid": "" }, { "name": "postsynaptic density membrane", "id": "GO:0098839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098839", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GFL9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GFL9" } ], "pmid": "" }, { "name": "Schaffer collateral - CA1 synapse", "id": "GO:0098685", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098685", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GFL9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GFL9" } ], "pmid": "" }, { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GFL9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GFL9" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GFL9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GFL9" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GFL9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GFL9" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GFL9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GFL9" } ], "pmid": "" }, { "name": "microtubule associated complex", "id": "GO:0005875", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005875", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GFL9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GFL9" } ], "pmid": "" } ], "biological_process": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GFL9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GFL9" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GFL9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GFL9" } ], "pmid": "" }, { "name": "chemical synaptic transmission", "id": "GO:0007268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007268", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GFL9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GFL9" } ], "pmid": "" }, { "name": "regulation of apoptotic process", "id": "GO:0042981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042981", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GFL9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GFL9" } ], "pmid": "" }, { "name": "dendrite morphogenesis", "id": "GO:0048813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048813", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GFL9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GFL9" } ], "pmid": "" }, { "name": "modulation of chemical synaptic transmission", "id": "GO:0050804", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050804", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GFL9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GFL9" } ], "pmid": "" }, { "name": "positive regulation of dendritic spine morphogenesis", "id": "GO:0061003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061003", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GFL9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GFL9" } ], "pmid": "" }, { "name": "positive regulation of dendrite development", "id": "GO:1900006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900006", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GFL9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GFL9" } ], "pmid": "" }, { "name": "regulation of innate immune response", "id": "GO:0045088", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045088", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GFL9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GFL9" } ], "pmid": "" }, { "name": "ammon gyrus development", "id": "GO:0021541", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021541", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GFL9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GFL9" } ], "pmid": "" }, { "name": "ventral spinal cord development", "id": "GO:0021517", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021517", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GFL9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GFL9" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GFL9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GFL9" } ], "pmid": "" }, { "name": "cellular response to cholesterol", "id": "GO:0071397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071397", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GFL9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GFL9" } ], "pmid": "" }, { "name": "hippocampus development", "id": "GO:0021766", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021766", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GFL9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GFL9" } ], "pmid": "" }, { "name": "cerebral cortex development", "id": "GO:0021987", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021987", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GFL9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GFL9" } ], "pmid": "" }, { "name": "positive regulation of protein kinase activity", "id": "GO:0045860", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045860", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GFL9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GFL9" } ], "pmid": "" }, { "name": "cellular response to growth factor stimulus", "id": "GO:0071363", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071363", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GFL9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GFL9" } ], "pmid": "" }, { "name": "layer formation in cerebral cortex", "id": "GO:0021819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021819", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GFL9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GFL9" } ], "pmid": "" }, { "name": "response to xenobiotic stimulus", "id": "GO:0009410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009410", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GFL9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GFL9" } ], "pmid": "" }, { "name": "reelin-mediated signaling pathway", "id": "GO:0038026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038026", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GFL9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GFL9" } ], "pmid": "" } ], "molecular_function": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GFL9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GFL9" } ], "pmid": "" }, { "name": "apolipoprotein binding", "id": "GO:0034185", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034185", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GFL9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GFL9" } ], "pmid": "" }, { "name": "calcium-dependent protein binding", "id": "GO:0048306", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048306", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GFL9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GFL9" } ], "pmid": "" }, { "name": "amyloid-beta binding", "id": "GO:0001540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001540", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GFL9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GFL9" } ], "pmid": "" }, { "name": "very-low-density lipoprotein particle receptor activity", "id": "GO:0030229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030229", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GFL9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GFL9" } ], "pmid": "" }, { "name": "reelin receptor activity", "id": "GO:0038025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038025", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GFL9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GFL9" } ], "pmid": "" }, { "name": "transmembrane signaling receptor activity", "id": "GO:0004888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004888", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GFL9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GFL9" } ], "pmid": "" }, { "name": "low-density lipoprotein particle receptor activity", "id": "GO:0005041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005041", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GFL9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GFL9" } ], "pmid": "" }, { "name": "kinesin binding", "id": "GO:0019894", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019894", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GFL9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GFL9" } ], "pmid": "" }, { "name": "high-density lipoprotein particle binding", "id": "GO:0008035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008035", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GFL9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GFL9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6GFL9-1", "start_pos": "250", "end_pos": "250", "site_lbl": "Thr250", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 250, "start_aa": "Thr", "end_pos": 250, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr250", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6GFL9-1" }, { "uniprot_canonical_ac": "A0A8I6ABV6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABV6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABV6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 716, "chemical_mass": 82981.0, "gene_names": "Znf431l5;LOC102551257", "protein_name": "", "disease": [], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABV6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABV6" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABV6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABV6" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABV6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABV6" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABV6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABV6" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABV6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABV6" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABV6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABV6" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ABV6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ABV6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6ABV6-1" }, { "uniprot_canonical_ac": "A0A8I6GIA2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GIA2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GIA2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 540, "chemical_mass": 61618.0, "gene_names": "Ildr1", "protein_name": "", "disease": [ { "disease_id": "DOID:0110500", "name": "autosomal recessive nonsyndromic deafness 42", "description": "An autosomal recessive nonsyndromic deafness that has_material_basis_in mutation in the ILDR1 gene on chromosome 3q13.", "url": "https://disease-ontology.org/term/DOID:0110500", "evidence": [ { "id": "0110500", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110500" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "bicellular tight junction", "id": "GO:0005923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005923", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GIA2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GIA2" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GIA2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GIA2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GIA2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GIA2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GIA2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GIA2" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GIA2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GIA2" } ], "pmid": "" }, { "name": "tricellular tight junction", "id": "GO:0061689", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061689", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GIA2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GIA2" } ], "pmid": "" }, { "name": "tight junction", "id": "GO:0070160", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070160", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GIA2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GIA2" } ], "pmid": "" } ], "molecular_function": [ { "name": "high-density lipoprotein particle receptor activity", "id": "GO:0070506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070506", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GIA2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GIA2" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GIA2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GIA2" } ], "pmid": "" } ], "biological_process": [ { "name": "protein localization to tricellular tight junction", "id": "GO:0061833", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061833", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GIA2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GIA2" } ], "pmid": "" }, { "name": "tricellular tight junction assembly", "id": "GO:1904274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904274", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GIA2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GIA2" } ], "pmid": "" }, { "name": "cellular response to leukemia inhibitory factor", "id": "GO:1990830", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990830", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GIA2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GIA2" } ], "pmid": "" }, { "name": "regulation of RNA splicing", "id": "GO:0043484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043484", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GIA2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GIA2" } ], "pmid": "" }, { "name": "response to fatty acid", "id": "GO:0070542", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070542", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GIA2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GIA2" } ], "pmid": "" }, { "name": "epithelial structure maintenance", "id": "GO:0010669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010669", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GIA2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GIA2" } ], "pmid": "" }, { "name": "positive regulation of peptide hormone secretion", "id": "GO:0090277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090277", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GIA2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GIA2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6GIA2-1", "start_pos": "514", "end_pos": "514", "site_lbl": "Thr514", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 514, "start_aa": "Thr", "end_pos": 514, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr514", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6GIA2-1" }, { "uniprot_canonical_ac": "A0A8I6A5P7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5P7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5P7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 105, "chemical_mass": 12027.0, "gene_names": "Dnal4;Dnal4-ps1", "protein_name": "Dynein light chain", "disease": [ { "disease_id": "DOID:0070639", "name": "mirror movements 3", "description": "A congenital mirror movement disorder that has_material_basis_in homozygous mutation in the DNAL4 gene on chromosome 22q13.", "url": "https://disease-ontology.org/term/DOID:0070639", "evidence": [ { "id": "0070639", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070639" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5P7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5P7" } ], "pmid": "" }, { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5P7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5P7" } ], "pmid": "" }, { "name": "dynein complex", "id": "GO:0030286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030286", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5P7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5P7" } ], "pmid": "" } ], "biological_process": [ { "name": "microtubule-based process", "id": "GO:0007017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007017", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5P7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5P7" } ], "pmid": "" } ], "molecular_function": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A5P7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A5P7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6A5P7-1" }, { "uniprot_canonical_ac": "A0A8I5ZQQ2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQQ2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 495, "chemical_mass": 56149.0, "gene_names": "Smarcd3;Smarcd3", "protein_name": "", "disease": [ { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 }, { "disease_id": "DOID:1925", "name": "Coffin-Siris syndrome", "description": "An autosomal dominant intellectual developmental disorder that is characterized by mental retardation associated with coarse facial features, hypertrichosis, sparse scalp hair, and hypoplastic or absent fifth fingernails or toenails.", "url": "https://disease-ontology.org/term/DOID:1925", "evidence": [ { "id": "1925", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1925" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQQ2" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQQ2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQQ2" } ], "pmid": "" }, { "name": "SWI/SNF complex", "id": "GO:0016514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016514", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQQ2" } ], "pmid": "" }, { "name": "npBAF complex", "id": "GO:0071564", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071564", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQQ2" } ], "pmid": "" }, { "name": "nBAF complex", "id": "GO:0071565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071565", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQQ2" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQQ2" } ], "pmid": "" } ], "biological_process": [ { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQQ2" } ], "pmid": "" }, { "name": "neural retina development", "id": "GO:0003407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003407", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQQ2" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQQ2" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQQ2" } ], "pmid": "" }, { "name": "positive regulation of G2/M transition of mitotic cell cycle", "id": "GO:0010971", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010971", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQQ2" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQQ2" } ], "pmid": "" }, { "name": "heart morphogenesis", "id": "GO:0003007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003007", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQQ2" } ], "pmid": "" }, { "name": "nucleosome disassembly", "id": "GO:0006337", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006337", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQQ2" } ], "pmid": "" }, { "name": "muscle cell differentiation", "id": "GO:0042692", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042692", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQQ2" } ], "pmid": "" }, { "name": "positive regulation of neuroblast proliferation", "id": "GO:0002052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002052", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQQ2" } ], "pmid": "" }, { "name": "cardiac right ventricle formation", "id": "GO:0003219", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003219", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQQ2" } ], "pmid": "" }, { "name": "secondary heart field specification", "id": "GO:0003139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003139", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQQ2" } ], "pmid": "" }, { "name": "positive regulation of smooth muscle cell differentiation", "id": "GO:0051152", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051152", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQQ2" } ], "pmid": "" } ], "molecular_function": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQQ2" } ], "pmid": "" }, { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQQ2" } ], "pmid": "" }, { "name": "signaling receptor binding", "id": "GO:0005102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005102", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQQ2" } ], "pmid": "" }, { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQQ2" } ], "pmid": "" }, { "name": "nuclear receptor binding", "id": "GO:0016922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016922", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQQ2" } ], "pmid": "" }, { "name": "transcription coregulator binding", "id": "GO:0001221", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001221", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQQ2" } ], "pmid": "" }, { "name": "DNA-binding transcription factor binding", "id": "GO:0140297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140297", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZQQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZQQ2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZQQ2-1" }, { "uniprot_canonical_ac": "A0A8I6ALB6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ALB6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ALB6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 963, "chemical_mass": 109890.0, "gene_names": "Tbc1d2b;RGD1307436;Tbc1d2b", "protein_name": "", "disease": [ { "disease_id": "DOID:0070651", "name": "neurodevelopmental disorder with seizures and gingival overgrowth", "description": "A syndrome characterized by a variable phenotype primarily including seizures, gingival overgrowth, a prominent mandible or cherubism, and mental deterioration that has_material_basis_in homozygous or compound heterozygous mutation in the TBC1D2B gene on chromosome 15q24. Other more variable features include coarse facial features, optic atrophy, sensorineural hearing loss, ataxia, hypotonia, delayed development or developmental regression, cerebellar or cerebral atrophy, and enlarged brain ventricles.", "url": "https://disease-ontology.org/term/DOID:0070651", "evidence": [ { "id": "0070651", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070651" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ALB6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ALB6" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ALB6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ALB6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ALB6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ALB6" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ALB6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ALB6" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ALB6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ALB6" } ], "pmid": "" } ], "biological_process": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ALB6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ALB6" } ], "pmid": "" } ], "molecular_function": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ALB6", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ALB6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6ALB6-1", "start_pos": "157", "end_pos": "157", "site_lbl": "Thr157", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 157, "start_aa": "Thr", "end_pos": 157, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr157", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I6ALB6-1", "start_pos": "477", "end_pos": "477", "site_lbl": "Thr477", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 477, "start_aa": "Thr", "end_pos": 477, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr477", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6ALB6-1" }, { "uniprot_canonical_ac": "A0A8I6G599-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G599", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G599" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1274, "chemical_mass": 145866.0, "gene_names": "Kiaa0825;Kiaa0825;RGD1560883", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6G599-1" }, { "uniprot_canonical_ac": "A0A8I6AG15-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AG15", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AG15" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 484, "chemical_mass": 53751.0, "gene_names": "Rdh13", "protein_name": "", "disease": [ { "disease_id": "DOID:14791", "name": "Leber congenital amaurosis", "description": "A retinal disease that is characterized by nystagmus, sluggish or no pupillary responses, and severe vision loss or blindness.", "url": "https://disease-ontology.org/term/DOID:14791", "evidence": [ { "id": "14791", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14791" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AG15", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AG15" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AG15", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AG15" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AG15", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AG15" } ], "pmid": "" } ], "biological_process": [ { "name": "retinal metabolic process", "id": "GO:0042574", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042574", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AG15", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AG15" } ], "pmid": "" }, { "name": "retina layer formation", "id": "GO:0010842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010842", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AG15", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AG15" } ], "pmid": "" }, { "name": "eye photoreceptor cell development", "id": "GO:0042462", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042462", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AG15", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AG15" } ], "pmid": "" }, { "name": "immune response-inhibiting cell surface receptor signaling pathway", "id": "GO:0002767", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002767", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AG15", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AG15" } ], "pmid": "" }, { "name": "response to high light intensity", "id": "GO:0009644", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009644", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AG15", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AG15" } ], "pmid": "" } ], "molecular_function": [ { "name": "all-trans-retinol dehydrogenase (NADP+) activity", "id": "GO:0052650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052650", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AG15", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AG15" } ], "pmid": "" }, { "name": "transmembrane signaling receptor activity", "id": "GO:0004888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004888", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AG15", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AG15" } ], "pmid": "" }, { "name": "immune receptor activity", "id": "GO:0140375", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140375", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AG15", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AG15" } ], "pmid": "" }, { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AG15", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AG15" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AG15-1" }, { "uniprot_canonical_ac": "A0A8I6AS40-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AS40", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AS40" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 211, "chemical_mass": 24418.0, "gene_names": "LOC108353077;Ralgdsl11;4930474N05Rikl;Cdrt15l2;LOC100363883;LOC102551632;LOC120097482;LOC134482318;LOC134482319;LOC134482320;LOC134482321;RGD1559804;RGD1565329;Ralgdsl10;Ralgdsl11;Ralgdsl6;Ralgdsl9", "protein_name": "", "disease": [], "molecular_function": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AS40", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AS40" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AS40-1" }, { "uniprot_canonical_ac": "A0A8I6AKA7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AKA7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AKA7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 116, "chemical_mass": 12420.0, "gene_names": "Igkvl14;Igkvl15;Igkvl11;Igkvl15;RGD1565617", "protein_name": "", "disease": [], "biological_process": [ { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AKA7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AKA7" } ], "pmid": "" } ], "cellular_component": [ { "name": "immunoglobulin complex", "id": "GO:0019814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019814", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AKA7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AKA7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AKA7-1" }, { "uniprot_canonical_ac": "A0A8I6G9B5-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G9B5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G9B5" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 912, "chemical_mass": 103209.0, "gene_names": "Vom2r44;Vom2r46;Vom2r46", "protein_name": "", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G9B5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G9B5" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G9B5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G9B5" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G9B5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G9B5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6G9B5-1" }, { "uniprot_canonical_ac": "A0A8I6B0P9-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B0P9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B0P9" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1040, "chemical_mass": 114886.0, "gene_names": "Ssh1;Ssh1", "protein_name": "Protein phosphatase Slingshot homolog 1", "disease": [ { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B0P9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B0P9" } ], "pmid": "" }, { "name": "protein serine/threonine phosphatase activity", "id": "GO:0004722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004722", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B0P9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B0P9" } ], "pmid": "" }, { "name": "phosphoprotein phosphatase activity", "id": "GO:0004721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004721", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B0P9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B0P9" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B0P9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B0P9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B0P9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B0P9" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B0P9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B0P9" } ], "pmid": "" }, { "name": "growth cone", "id": "GO:0030426", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030426", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B0P9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B0P9" } ], "pmid": "" }, { "name": "cell leading edge", "id": "GO:0031252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031252", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B0P9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B0P9" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B0P9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B0P9" } ], "pmid": "" }, { "name": "cell projection", "id": "GO:0042995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042995", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B0P9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B0P9" } ], "pmid": "" }, { "name": "cleavage furrow", "id": "GO:0032154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032154", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B0P9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B0P9" } ], "pmid": "" }, { "name": "midbody", "id": "GO:0030496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030496", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B0P9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B0P9" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of actin filament polymerization", "id": "GO:0030837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030837", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B0P9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B0P9" } ], "pmid": "" }, { "name": "excitatory chemical synaptic transmission", "id": "GO:0098976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098976", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B0P9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B0P9" } ], "pmid": "" }, { "name": "positive regulation of excitatory postsynaptic potential", "id": "GO:2000463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000463", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B0P9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B0P9" } ], "pmid": "" }, { "name": "cell morphogenesis", "id": "GO:0000902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000902", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B0P9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B0P9" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B0P9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B0P9" } ], "pmid": "" }, { "name": "protein dephosphorylation", "id": "GO:0006470", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006470", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B0P9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B0P9" } ], "pmid": "" }, { "name": "positive regulation of synaptic plasticity", "id": "GO:0031915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031915", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B0P9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B0P9" } ], "pmid": "" }, { "name": "positive regulation of vascular associated smooth muscle cell migration", "id": "GO:1904754", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904754", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B0P9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B0P9" } ], "pmid": "" }, { "name": "regulation of protein metabolic process", "id": "GO:0051246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051246", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B0P9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B0P9" } ], "pmid": "" }, { "name": "positive regulation of AMPA glutamate receptor clustering", "id": "GO:1904719", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904719", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B0P9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B0P9" } ], "pmid": "" }, { "name": "cellular response to ATP", "id": "GO:0071318", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071318", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6B0P9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6B0P9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6B0P9-1", "start_pos": "11", "end_pos": "11", "site_lbl": "Thr11", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 11, "start_aa": "Thr", "end_pos": 11, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr11", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I6B0P9-1", "start_pos": "915", "end_pos": "915", "site_lbl": "Thr915", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 915, "start_aa": "Thr", "end_pos": 915, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr915", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I6B0P9-1", "start_pos": "951", "end_pos": "951", "site_lbl": "Thr951", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "reported site T928 is on non-canonical isoform A0A8I6A2G7-1 which maps to canonical isoform site A0A8I6B0P9-1:951", "icn3d_view": {}, "start_pos": 951, "start_aa": "Thr", "end_pos": 951, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr951", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6B0P9-1" }, { "uniprot_canonical_ac": "A0A8I6AGS4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AGS4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AGS4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1620, "chemical_mass": 177038.0, "gene_names": "Abi3bp", "protein_name": "", "disease": [], "cellular_component": [ { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AGS4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AGS4" } ], "pmid": "" }, { "name": "lamellipodium", "id": "GO:0030027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030027", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AGS4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AGS4" } ], "pmid": "" }, { "name": "dendritic spine", "id": "GO:0043197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043197", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AGS4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AGS4" } ], "pmid": "" }, { "name": "dendritic shaft", "id": "GO:0043198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043198", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AGS4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AGS4" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AGS4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AGS4" } ], "pmid": "" }, { "name": "interstitial matrix", "id": "GO:0005614", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005614", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AGS4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AGS4" } ], "pmid": "" } ], "molecular_function": [ { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AGS4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AGS4" } ], "pmid": "" }, { "name": "heparin binding", "id": "GO:0008201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008201", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AGS4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AGS4" } ], "pmid": "" }, { "name": "collagen binding", "id": "GO:0005518", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005518", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AGS4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AGS4" } ], "pmid": "" }, { "name": "glycosaminoglycan binding", "id": "GO:0005539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005539", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AGS4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AGS4" } ], "pmid": "" } ], "biological_process": [ { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AGS4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AGS4" } ], "pmid": "" }, { "name": "regulation of dendritic spine morphogenesis", "id": "GO:0061001", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061001", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AGS4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AGS4" } ], "pmid": "" }, { "name": "positive regulation of cellular senescence", "id": "GO:2000774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000774", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AGS4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AGS4" } ], "pmid": "" }, { "name": "defense response to tumor cell", "id": "GO:0002357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002357", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AGS4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AGS4" } ], "pmid": "" }, { "name": "regulation of postsynaptic density assembly", "id": "GO:0099151", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099151", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AGS4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AGS4" } ], "pmid": "" }, { "name": "extracellular matrix organization", "id": "GO:0030198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030198", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AGS4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AGS4" } ], "pmid": "" }, { "name": "positive regulation of cell-substrate adhesion", "id": "GO:0010811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010811", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AGS4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AGS4" } ], "pmid": "" }, { "name": "negative regulation of connective tissue replacement involved in inflammatory response wound healing", "id": "GO:1904597", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904597", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AGS4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AGS4" } ], "pmid": "" }, { "name": "negative regulation of cell population proliferation", "id": "GO:0008285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008285", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AGS4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AGS4" } ], "pmid": "" }, { "name": "positive regulation of cardiocyte differentiation", "id": "GO:1905209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905209", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AGS4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AGS4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AGS4-1" }, { "uniprot_canonical_ac": "A0A8I6ATT3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATT3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATT3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 949, "chemical_mass": 103684.0, "gene_names": "Cnnm1;Cnnm1", "protein_name": "Metal transporter", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATT3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATT3" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATT3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATT3" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATT3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATT3" } ], "pmid": "" } ], "biological_process": [ { "name": "monoatomic ion transport", "id": "GO:0006811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006811", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATT3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATT3" } ], "pmid": "" }, { "name": "magnesium ion homeostasis", "id": "GO:0010960", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010960", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATT3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATT3" } ], "pmid": "" } ], "molecular_function": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ATT3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ATT3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6ATT3-1" }, { "uniprot_canonical_ac": "A0A8I5ZVY6-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZVY6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZVY6" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 792, "chemical_mass": 89947.0, "gene_names": "Rint1;RGD1560433;Rint1", "protein_name": "RAD50-interacting protein 1", "disease": [ { "disease_id": "DOID:0080716", "name": "infantile liver failure syndrome", "description": "A syndrome that is characterized by acute liver failure, that occurs in the first year of life, which manifests with failure to thrive, hypotonia, moderate global developmental delay, seizures, abnormal liver function tests, microcytic anemia and elevated serum lactate.", "url": "https://disease-ontology.org/term/DOID:0080716", "evidence": [ { "id": "0080716", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080716" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "Dsl1/NZR complex", "id": "GO:0070939", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070939", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZVY6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZVY6" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZVY6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZVY6" } ], "pmid": "" } ], "biological_process": [ { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZVY6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZVY6" } ], "pmid": "" }, { "name": "retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum", "id": "GO:0006890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006890", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZVY6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZVY6" } ], "pmid": "" }, { "name": "regulation of ER to Golgi vesicle-mediated transport", "id": "GO:0060628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060628", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZVY6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZVY6" } ], "pmid": "" }, { "name": "mitotic G2 DNA damage checkpoint signaling", "id": "GO:0007095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007095", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZVY6", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZVY6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZVY6-1" }, { "uniprot_canonical_ac": "A0A8I6GJS5-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GJS5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GJS5" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 2148, "chemical_mass": 229827.0, "gene_names": "G2;D430041D05Rikl;G2;LOC100362814;RGD1310754", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6GJS5-1", "start_pos": "105", "end_pos": "105", "site_lbl": "Thr105", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 105, "start_aa": "Thr", "end_pos": 105, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr105", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I6GJS5-1", "start_pos": "1180", "end_pos": "1180", "site_lbl": "Thr1180", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1180, "start_aa": "Thr", "end_pos": 1180, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1180", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I6GJS5-1", "start_pos": "339", "end_pos": "339", "site_lbl": "Thr339", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 339, "start_aa": "Thr", "end_pos": 339, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr339", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6GJS5-1" }, { "uniprot_canonical_ac": "A0A8I6AR03-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AR03", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AR03" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1079, "chemical_mass": 120555.0, "gene_names": "AABR07028615.1;Frmd4a;AABR07028615.1;Frmd4a;RGD1309050", "protein_name": "", "disease": [], "biological_process": [ { "name": "negative regulation of protein secretion", "id": "GO:0050709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050709", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AR03", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AR03" } ], "pmid": "" }, { "name": "positive regulation of protein secretion", "id": "GO:0050714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050714", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AR03", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AR03" } ], "pmid": "" }, { "name": "establishment of epithelial cell polarity", "id": "GO:0090162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090162", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AR03", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AR03" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AR03", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AR03" } ], "pmid": "" }, { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AR03", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AR03" } ], "pmid": "" }, { "name": "bicellular tight junction", "id": "GO:0005923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005923", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AR03", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AR03" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AR03", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AR03" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AR03", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AR03" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6AR03-1", "start_pos": "1032", "end_pos": "1032", "site_lbl": "Thr1032", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1032, "start_aa": "Thr", "end_pos": 1032, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1032", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6AR03-1" }, { "uniprot_canonical_ac": "A0A8I6ALD1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ALD1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ALD1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1957, "chemical_mass": 217775.0, "gene_names": "Eml6", "protein_name": "", "disease": [], "cellular_component": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ALD1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ALD1" } ], "pmid": "" } ], "molecular_function": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ALD1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ALD1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6ALD1-1", "start_pos": "1439", "end_pos": "1439", "site_lbl": "Thr1439", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1439, "start_aa": "Thr", "end_pos": 1439, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1439", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6ALD1-1" }, { "uniprot_canonical_ac": "A0A8I6GGQ4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GGQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GGQ4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 374, "chemical_mass": 41385.0, "gene_names": "Tmeff2;Tmeff2", "protein_name": "Tomoregulin-2", "disease": [ { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:11054", "name": "urinary bladder cancer", "description": "An urinary system cancer that results_in malignant growth located_in the urinary bladder.", "url": "https://disease-ontology.org/term/DOID:11054", "evidence": [ { "id": "11054", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11054" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GGQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GGQ4" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of cell migration", "id": "GO:0030336", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030336", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GGQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GGQ4" } ], "pmid": "" }, { "name": "negative regulation of integrin biosynthetic process", "id": "GO:0045720", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045720", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GGQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GGQ4" } ], "pmid": "" }, { "name": "negative regulation of stress fiber assembly", "id": "GO:0051497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051497", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GGQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GGQ4" } ], "pmid": "" }, { "name": "wound healing, spreading of cells", "id": "GO:0044319", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044319", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GGQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GGQ4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6GGQ4-1" }, { "uniprot_canonical_ac": "A0A8I5ZWZ1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZWZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZWZ1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1109, "chemical_mass": 121508.0, "gene_names": "Radil", "protein_name": "Ras-associating and dilute domain-containing protein", "disease": [], "biological_process": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZWZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZWZ1" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZWZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZWZ1" } ], "pmid": "" }, { "name": "neural crest cell migration", "id": "GO:0001755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001755", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZWZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZWZ1" } ], "pmid": "" }, { "name": "substrate adhesion-dependent cell spreading", "id": "GO:0034446", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034446", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZWZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZWZ1" } ], "pmid": "" } ], "cellular_component": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZWZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZWZ1" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZWZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZWZ1" } ], "pmid": "" } ], "molecular_function": [ { "name": "GTPase binding", "id": "GO:0051020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051020", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZWZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZWZ1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I5ZWZ1-1", "start_pos": "252", "end_pos": "252", "site_lbl": "Thr252", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 252, "start_aa": "Thr", "end_pos": 252, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr252", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I5ZWZ1-1", "start_pos": "261", "end_pos": "261", "site_lbl": "Thr261", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 261, "start_aa": "Thr", "end_pos": 261, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr261", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I5ZWZ1-1", "start_pos": "952", "end_pos": "952", "site_lbl": "Thr952", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" }, { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "reported site T943 is on non-canonical isoform A0ABK0LB92-1 which maps to canonical isoform site A0A8I5ZWZ1-1:952", "icn3d_view": {}, "start_pos": 952, "start_aa": "Thr", "end_pos": 952, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr952", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I5ZWZ1-1" }, { "uniprot_canonical_ac": "A0A8I5ZTE2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTE2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTE2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 726, "chemical_mass": 82454.0, "gene_names": "Zfp108", "protein_name": "", "disease": [], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTE2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTE2" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTE2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTE2" } ], "pmid": "" }, { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTE2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTE2" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTE2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTE2" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTE2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTE2" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTE2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTE2" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTE2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTE2" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTE2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTE2" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTE2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTE2" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTE2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTE2" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZTE2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZTE2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZTE2-1" }, { "uniprot_canonical_ac": "A0A8I6AVC5-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AVC5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AVC5" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1316, "chemical_mass": 141106.0, "gene_names": "Ltbp3;Ltbp3", "protein_name": "Latent-transforming growth factor beta-binding protein 3", "disease": [ { "disease_id": "DOID:0090143", "name": "brachyolmia-amelogenesis imperfecta syndrome", "description": "A syndrome characterized by skeletal dysplasia (broad ilia, elongated femoral necks with coxa valga, scoliosis), mild platyspondyly, short trunked short stature, and amelogenesis imperfecta that has_material_basis_in autosomal recessive inheritance of homozygous or compound heterozygous mutation in the latent transforming growth factor beta binding protein 3 gene (LTBP3) on chromosome 11q13.", "url": "https://disease-ontology.org/term/DOID:0090143", "evidence": [ { "id": "0090143", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0090143" } ], "weight": 0.0 }, { "disease_id": "DOID:0111727", "name": "geleophysic dysplasia 3", "description": "A geleophysic dysplasia that has_material_basis_in heterozygous mutation in the LTBP3 gene on chromosome 11q13.1.", "url": "https://disease-ontology.org/term/DOID:0111727", "evidence": [ { "id": "0111727", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111727" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AVC5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AVC5" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AVC5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AVC5" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AVC5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AVC5" } ], "pmid": "" } ], "molecular_function": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AVC5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AVC5" } ], "pmid": "" }, { "name": "transforming growth factor beta binding", "id": "GO:0050431", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050431", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AVC5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AVC5" } ], "pmid": "" } ], "biological_process": [ { "name": "transforming growth factor beta receptor signaling pathway", "id": "GO:0007179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007179", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AVC5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AVC5" } ], "pmid": "" }, { "name": "positive regulation of bone resorption", "id": "GO:0045780", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045780", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AVC5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AVC5" } ], "pmid": "" }, { "name": "skeletal system development", "id": "GO:0001501", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001501", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AVC5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AVC5" } ], "pmid": "" }, { "name": "bone remodeling", "id": "GO:0046849", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046849", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AVC5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AVC5" } ], "pmid": "" }, { "name": "bone morphogenesis", "id": "GO:0060349", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060349", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AVC5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AVC5" } ], "pmid": "" }, { "name": "negative regulation of chondrocyte differentiation", "id": "GO:0032331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032331", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AVC5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AVC5" } ], "pmid": "" }, { "name": "negative regulation of bone mineralization", "id": "GO:0030502", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030502", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AVC5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AVC5" } ], "pmid": "" }, { "name": "lung saccule development", "id": "GO:0060430", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060430", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AVC5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AVC5" } ], "pmid": "" }, { "name": "positive regulation of mesenchymal stem cell proliferation", "id": "GO:1902462", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902462", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AVC5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AVC5" } ], "pmid": "" }, { "name": "positive regulation of mesenchymal stem cell differentiation", "id": "GO:2000741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000741", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AVC5", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AVC5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AVC5-1" }, { "uniprot_canonical_ac": "A0A8I6AHI4-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 750, "chemical_mass": 85765.0, "gene_names": "Ezh2", "protein_name": "Histone-lysine N-methyltransferase EZH2", "disease": [ { "disease_id": "DOID:0050745", "name": "diffuse large B-cell lymphoma", "description": "A large B-cell lymphoma that is consisting of medium-sized to large B cells with a diffuse growth pattern.", "url": "https://disease-ontology.org/term/DOID:0050745", "evidence": [ { "id": "0050745", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050745" } ], "weight": 0.0 }, { "disease_id": "DOID:0050860", "name": "colorectal adenoma", "description": "An intestinal benign neoplasm that has_material_basis_in epithelial tissue of glandular origin and is located_in colon and located_in rectum.", "url": "https://disease-ontology.org/term/DOID:0050860", "evidence": [ { "id": "0050860", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050860" } ], "weight": 0.0 }, { "disease_id": "DOID:0050861", "name": "colorectal adenocarcinoma", "description": "A colorectal carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:0050861", "evidence": [ { "id": "0050861", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050861" } ], "weight": 0.0 }, { "disease_id": "DOID:0050866", "name": "oral squamous cell carcinoma", "description": "An oral cavity cancer that has_material_basis_in squamous cells.", "url": "https://disease-ontology.org/term/DOID:0050866", "evidence": [ { "id": "0050866", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050866" } ], "weight": 0.0 }, { "disease_id": "DOID:0050888", "name": "syndromic intellectual disability", "description": "An intellectual disability that is characterized by the presence of associated medical and behavioral sign and symptoms.", "url": "https://disease-ontology.org/term/DOID:0050888", "evidence": [ { "id": "0050888", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050888" } ], "weight": 0.0 }, { "disease_id": "DOID:0050908", "name": "myelodysplastic syndrome", "description": "A bone marrow cancer that is characterized by under production of white blood cells, red blood cells and platelets.", "url": "https://disease-ontology.org/term/DOID:0050908", "evidence": [ { "id": "0050908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050908" } ], "weight": 0.0 }, { "disease_id": "DOID:0080188", "name": "chronic myelomonocytic leukemia", "description": "A chronic leukemia characterized by monocytosis, increased monocytes in the bone marrow, variable degrees of dysplasia, but an absence of immature granulocytes in the blood.", "url": "https://disease-ontology.org/term/DOID:0080188", "evidence": [ { "id": "0080188", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080188" } ], "weight": 0.0 }, { "disease_id": "DOID:0080199", "name": "colorectal carcinoma", "description": "A colorectal cancer that arises from the colon or rectum and invades through the muscularis mucosa into the submucosa.", "url": "https://disease-ontology.org/term/DOID:0080199", "evidence": [ { "id": "0080199", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080199" } ], "weight": 0.0 }, { "disease_id": "DOID:0080208", "name": "metabolic dysfunction-associated steatotic liver disease", "description": "A steatotic liver disease characterized by at least one of five specified cardiometabolic risk factors and no other discernible cause with normal to no alcohol use. The five cardiometabolic risk factors are: (1) higher than normal body mass index or waist circumference; (2) higher than normal serum glucose or glycated hemoglobin level, or type 2 diabetes; (3) higher than normal blood pressure or hypertensive treatment; (4) higher than normal plasma triglycerides or lipid lowering treatment; and (5) lower than normal plasma high-density lipoprotein cholesterol.", "url": "https://disease-ontology.org/term/DOID:0080208", "evidence": [ { "id": "0080208", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080208" } ], "weight": 0.0 }, { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ], "weight": 0.0 }, { "disease_id": "DOID:11054", "name": "urinary bladder cancer", "description": "An urinary system cancer that results_in malignant growth located_in the urinary bladder.", "url": "https://disease-ontology.org/term/DOID:11054", "evidence": [ { "id": "11054", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11054" } ], "weight": 0.0 }, { "disease_id": "DOID:127", "name": "leiomyoma", "description": "A cell type benign neoplasm that is a benign tumor of smooth muscle cells.", "url": "https://disease-ontology.org/term/DOID:127", "evidence": [ { "id": "127", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:127" } ], "weight": 0.0 }, { "disease_id": "DOID:1324", "name": "lung cancer", "description": "A respiratory system cancer that is located_in the lung.", "url": "https://disease-ontology.org/term/DOID:1324", "evidence": [ { "id": "1324", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1324" } ], "weight": 0.0 }, { "disease_id": "DOID:14731", "name": "Weaver syndrome", "description": "A syndrome that is characterized by prenatal and postnatal overgrowth, accelerated osseous maturation, characteristic craniofacial appearance, and developmental delay and has_material_basis_in heterozygous mutation in the EZH2 gene on chromosome 7q36.", "url": "https://disease-ontology.org/term/DOID:14731", "evidence": [ { "id": "14731", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14731" } ], "weight": 0.0 }, { "disease_id": "DOID:1793", "name": "pancreatic cancer", "description": "An endocrine gland cancer located_in the pancreas.", "url": "https://disease-ontology.org/term/DOID:1793", "evidence": [ { "id": "1793", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1793" } ], "weight": 0.0 }, { "disease_id": "DOID:219", "name": "colon cancer", "description": "A colorectal cancer that is located_in the colon.", "url": "https://disease-ontology.org/term/DOID:219", "evidence": [ { "id": "219", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:219" } ], "weight": 0.0 }, { "disease_id": "DOID:289", "name": "endometriosis", "description": "A female reproductive system disease characterized by the growth of endometrial tissue outside the uterine body.", "url": "https://disease-ontology.org/term/DOID:289", "evidence": [ { "id": "289", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:289" } ], "weight": 0.0 }, { "disease_id": "DOID:3008", "name": "invasive ductal carcinoma", "description": "A breast ductal carcinoma that is characterized by infiltration into the fibrous or fatty tissue of the breast outside of the duct where it originated.", "url": "https://disease-ontology.org/term/DOID:3008", "evidence": [ { "id": "3008", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3008" } ], "weight": 0.0 }, { "disease_id": "DOID:3068", "name": "glioblastoma", "description": "A malignant astrocytoma characterized by the presence of small areas of necrotizing tissue that is surrounded by anaplastic cells as well as the presence of hyperplastic blood vessels, and that has_material_basis_in abnormally proliferating cells derives_from multiple cell types including astrocytes and oligondroctyes.", "url": "https://disease-ontology.org/term/DOID:3068", "evidence": [ { "id": "3068", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3068" } ], "weight": 0.0 }, { "disease_id": "DOID:3347", "name": "osteosarcoma", "description": "A bone sarcoma that is located_in bone that has_material_basis_in cells of mesenchymal origin. It usually involves bones and less frequently extraosseous sites. It often involves the long bones (particularly distal femur, proximal tibia, and proximal humerus).", "url": "https://disease-ontology.org/term/DOID:3347", "evidence": [ { "id": "3347", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3347" } ], "weight": 0.0 }, { "disease_id": "DOID:3748", "name": "esophagus squamous cell carcinoma", "description": "An esophageal carcinoma that derives_from epithelial squamous cells located_in the esophagus.", "url": "https://disease-ontology.org/term/DOID:3748", "evidence": [ { "id": "3748", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3748" } ], "weight": 0.0 }, { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 }, { "disease_id": "DOID:3910", "name": "lung adenocarcinoma", "description": "A lung non-small cell carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:3910", "evidence": [ { "id": "3910", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3910" } ], "weight": 0.0 }, { "disease_id": "DOID:4947", "name": "cholangiocarcinoma", "description": "A bile duct adenocarcinoma that has_material_basis_in bile duct epithelial cells.", "url": "https://disease-ontology.org/term/DOID:4947", "evidence": [ { "id": "4947", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4947" } ], "weight": 0.0 }, { "disease_id": "DOID:4971", "name": "myelofibrosis", "description": "A myeloid neoplasm that is located in the bone marrow which results in bone marrow being replaced by fibrous (scar) tissue.", "url": "https://disease-ontology.org/term/DOID:4971", "evidence": [ { "id": "4971", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4971" } ], "weight": 0.0 }, { "disease_id": "DOID:5176", "name": "renal Wilms' tumor", "description": "", "url": "https://disease-ontology.org/term/DOID:5176", "evidence": [ { "id": "5176", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5176" } ], "weight": 0.0 }, { "disease_id": "DOID:6000", "name": "congestive heart failure", "description": "A heart disease that is characterized by any structural or functional cardiac disorder that impairs the ability of the heart to fill with or pump a sufficient amount of blood throughout the body.", "url": "https://disease-ontology.org/term/DOID:6000", "evidence": [ { "id": "6000", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6000" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:707", "name": "B-cell lymphoma", "description": "A non-Hodgkin lymphoma that has_material_basis_in B cells.", "url": "https://disease-ontology.org/term/DOID:707", "evidence": [ { "id": "707", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:707" } ], "weight": 0.0 }, { "disease_id": "DOID:7474", "name": "malignant pleural mesothelioma", "description": "A pleural cancer that has_material_basis_in mesothelium cells.", "url": "https://disease-ontology.org/term/DOID:7474", "evidence": [ { "id": "7474", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7474" } ], "weight": 0.0 }, { "disease_id": "DOID:7693", "name": "abdominal aortic aneurysm", "description": "An aortic aneurysm that is located_in the abdominal aorta.", "url": "https://disease-ontology.org/term/DOID:7693", "evidence": [ { "id": "7693", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7693" } ], "weight": 0.0 }, { "disease_id": "DOID:8552", "name": "chronic myeloid leukemia", "description": "A myeloid leukemia that is characterized by over production of white blood cells.", "url": "https://disease-ontology.org/term/DOID:8552", "evidence": [ { "id": "8552", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8552" } ], "weight": 0.0 }, { "disease_id": "DOID:8761", "name": "acute megakaryocytic leukemia", "description": "An acute myeloid leukemia that derives from blood-forming tissue in which megakaryocytes proliferate in the bone marrow and circulate in the blood in large numbers.", "url": "https://disease-ontology.org/term/DOID:8761", "evidence": [ { "id": "8761", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8761" } ], "weight": 0.0 }, { "disease_id": "DOID:9119", "name": "acute myeloid leukemia", "description": "A myeloid leukemia that is characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal blood cells.", "url": "https://disease-ontology.org/term/DOID:9119", "evidence": [ { "id": "9119", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9119" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 }, { "disease_id": "DOID:9261", "name": "nasopharynx carcinoma", "description": "A pharynx cancer that is located in the nasopharynx, the uppermost region of the pharynx or throat, where the nasal passages and auditory tubes join the remainder of the upper respiratory tract.", "url": "https://disease-ontology.org/term/DOID:9261", "evidence": [ { "id": "9261", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9261" } ], "weight": 0.0 }, { "disease_id": "DOID:9952", "name": "acute lymphoblastic leukemia", "description": "A acute leukemia that is characterized by over production of lymphoblasts.", "url": "https://disease-ontology.org/term/DOID:9952", "evidence": [ { "id": "9952", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9952" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "histone H3K27 methyltransferase activity", "id": "GO:0046976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046976", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "histone H3K27 trimethyltransferase activity", "id": "GO:0140951", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140951", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "ribonucleoprotein complex binding", "id": "GO:0043021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043021", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "RNA polymerase II core promoter sequence-specific DNA binding", "id": "GO:0000979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000979", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "chromatin DNA binding", "id": "GO:0031490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031490", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "histone methyltransferase activity", "id": "GO:0042054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042054", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "nucleosome binding", "id": "GO:0031491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031491", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "protein-lysine N-methyltransferase activity", "id": "GO:0016279", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016279", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "promoter-specific chromatin binding", "id": "GO:1990841", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990841", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "primary miRNA binding", "id": "GO:0070878", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070878", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "transcription corepressor binding", "id": "GO:0001222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001222", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "lncRNA binding", "id": "GO:0106222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106222", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "ESC/E(Z) complex", "id": "GO:0035098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035098", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "chromatin silencing complex", "id": "GO:0005677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005677", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "heterochromatin", "id": "GO:0000792", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000792", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "pronucleus", "id": "GO:0045120", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045120", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "pericentric heterochromatin", "id": "GO:0005721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005721", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "PcG protein complex", "id": "GO:0031519", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031519", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "chromosomal region", "id": "GO:0098687", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098687", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "heterochromatin formation", "id": "GO:0031507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031507", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "negative regulation of epidermal cell differentiation", "id": "GO:0045605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045605", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "subtelomeric heterochromatin formation", "id": "GO:0031509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031509", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "negative regulation of gene expression", "id": "GO:0010629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010629", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "positive regulation of cell migration", "id": "GO:0030335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030335", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "regulation of cell population proliferation", "id": "GO:0042127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042127", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "positive regulation of GTPase activity", "id": "GO:0043547", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043547", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "hippocampus development", "id": "GO:0021766", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021766", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "positive regulation of MAP kinase activity", "id": "GO:0043406", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043406", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "cerebellar cortex development", "id": "GO:0021695", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021695", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "response to estradiol", "id": "GO:0032355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032355", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "cellular response to hydrogen peroxide", "id": "GO:0070301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070301", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "B cell differentiation", "id": "GO:0030183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030183", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "regulation of circadian rhythm", "id": "GO:0042752", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042752", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "rhythmic process", "id": "GO:0048511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048511", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "positive regulation of protein serine/threonine kinase activity", "id": "GO:0071902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071902", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "cardiac muscle hypertrophy in response to stress", "id": "GO:0014898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014898", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "negative regulation of cytokine production involved in inflammatory response", "id": "GO:1900016", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900016", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "regulation of protein phosphorylation", "id": "GO:0001932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001932", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "positive regulation of epithelial to mesenchymal transition", "id": "GO:0010718", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010718", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "negative regulation of G1/S transition of mitotic cell cycle", "id": "GO:2000134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000134", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "negative regulation of gene expression, epigenetic", "id": "GO:0045814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045814", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "liver regeneration", "id": "GO:0097421", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097421", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "cellular response to trichostatin A", "id": "GO:0035984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035984", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "cell development", "id": "GO:0048468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048468", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "regulation of neurogenesis", "id": "GO:0050767", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050767", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "regulation of gliogenesis", "id": "GO:0014013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014013", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration", "id": "GO:0014834", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014834", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "hepatocyte homeostasis", "id": "GO:0036333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036333", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "negative regulation of striated muscle cell differentiation", "id": "GO:0051154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051154", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "response to tetrachloromethane", "id": "GO:1904772", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904772", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "positive regulation of cell cycle G1/S phase transition", "id": "GO:1902808", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902808", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "DNA methylation-dependent constitutive heterochromatin formation", "id": "GO:0006346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006346", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "gene expression", "id": "GO:0010467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010467", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "G1 to G0 transition", "id": "GO:0070314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070314", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "positive regulation of dendrite development", "id": "GO:1900006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900006", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "negative regulation of transcription elongation by RNA polymerase II", "id": "GO:0034244", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034244", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "regulatory ncRNA-mediated heterochromatin formation", "id": "GO:0031048", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031048", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "negative regulation of retinoic acid receptor signaling pathway", "id": "GO:0048387", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048387", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "protein localization to chromatin", "id": "GO:0071168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071168", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "synaptic transmission, GABAergic", "id": "GO:0051932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051932", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "regulation of kidney development", "id": "GO:0090183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090183", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "facultative heterochromatin formation", "id": "GO:0140718", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140718", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" }, { "name": "constitutive heterochromatin formation", "id": "GO:0140719", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140719", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AHI4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AHI4-1" }, { "uniprot_canonical_ac": "A0A8I6A1C9-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1C9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1C9" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 321, "chemical_mass": 35668.0, "gene_names": "Fhl3", "protein_name": "Four and a half LIM domains protein 3", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1C9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1C9" } ], "pmid": "" }, { "name": "stress fiber", "id": "GO:0001725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001725", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1C9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1C9" } ], "pmid": "" }, { "name": "Z disc", "id": "GO:0030018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030018", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1C9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1C9" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1C9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1C9" } ], "pmid": "" }, { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1C9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1C9" } ], "pmid": "" }, { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1C9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1C9" } ], "pmid": "" } ], "biological_process": [ { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1C9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1C9" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1C9", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1C9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6A1C9-1" }, { "uniprot_canonical_ac": "A0A8I6GJQ1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GJQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GJQ1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 609, "chemical_mass": 67965.0, "gene_names": "Adamtsl5", "protein_name": "", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GJQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GJQ1" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GJQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GJQ1" } ], "pmid": "" }, { "name": "microfibril", "id": "GO:0001527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001527", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GJQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GJQ1" } ], "pmid": "" } ], "biological_process": [ { "name": "extracellular matrix organization", "id": "GO:0030198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030198", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GJQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GJQ1" } ], "pmid": "" } ], "molecular_function": [ { "name": "heparin binding", "id": "GO:0008201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008201", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GJQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GJQ1" } ], "pmid": "" }, { "name": "microfibril binding", "id": "GO:0050436", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050436", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GJQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GJQ1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6GJQ1-1", "start_pos": "412", "end_pos": "412", "site_lbl": "Thr412", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 412, "start_aa": "Thr", "end_pos": 412, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr412", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I6GJQ1-1", "start_pos": "525", "end_pos": "525", "site_lbl": "Thr525", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "reported site T384 is on non-canonical isoform A0ABK0LBW0-1 which maps to canonical isoform site A0A8I6GJQ1-1:525", "icn3d_view": {}, "start_pos": 525, "start_aa": "Thr", "end_pos": 525, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr525", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6GJQ1-1" }, { "uniprot_canonical_ac": "A0A8I6AQU2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQU2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQU2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 936, "chemical_mass": 105577.0, "gene_names": "Kdm7a;Jhdm1d;Kdm7a", "protein_name": "Lysine-specific demethylase 7A", "disease": [ { "disease_id": "DOID:0060309", "name": "syndromic X-linked intellectual disability", "description": "A syndromic intellectual disability characterized by an X-linked inheritance pattern.", "url": "https://disease-ontology.org/term/DOID:0060309", "evidence": [ { "id": "0060309", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060309" } ], "weight": 0.0 }, { "disease_id": "DOID:1909", "name": "melanoma", "description": "A cell type cancer that has_material_basis_in abnormally proliferating cells derives_from melanocytes which are found in skin, the bowel and the eye.", "url": "https://disease-ontology.org/term/DOID:1909", "evidence": [ { "id": "1909", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1909" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQU2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQU2" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQU2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQU2" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQU2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQU2" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQU2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQU2" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQU2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQU2" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQU2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQU2" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQU2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQU2" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQU2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQU2" } ], "pmid": "" }, { "name": "dioxygenase activity", "id": "GO:0051213", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051213", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQU2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQU2" } ], "pmid": "" }, { "name": "histone demethylase activity", "id": "GO:0032452", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032452", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQU2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQU2" } ], "pmid": "" }, { "name": "histone H4K20 demethylase activity", "id": "GO:0035575", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035575", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQU2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQU2" } ], "pmid": "" }, { "name": "histone H3K36 demethylase activity", "id": "GO:0051864", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051864", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQU2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQU2" } ], "pmid": "" }, { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQU2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQU2" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQU2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQU2" } ], "pmid": "" }, { "name": "2-oxoglutarate-dependent dioxygenase activity", "id": "GO:0016706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016706", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQU2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQU2" } ], "pmid": "" }, { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQU2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQU2" } ], "pmid": "" }, { "name": "histone H3K27me2/H3K27me3 demethylase activity", "id": "GO:0071558", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071558", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQU2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQU2" } ], "pmid": "" }, { "name": "histone H3K9 demethylase activity", "id": "GO:0032454", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032454", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQU2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQU2" } ], "pmid": "" }, { "name": "histone H3K9me/H3K9me2 demethylase activity", "id": "GO:0140683", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140683", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AQU2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AQU2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AQU2-1" }, { "uniprot_canonical_ac": "A0A8I6GEK3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GEK3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GEK3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1510, "chemical_mass": 174671.0, "gene_names": "Efcab6", "protein_name": "EF-hand calcium-binding domain-containing protein 6", "disease": [], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GEK3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GEK3" } ], "pmid": "" }, { "name": "sperm flagellum", "id": "GO:0036126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036126", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GEK3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GEK3" } ], "pmid": "" }, { "name": "axonemal A tubule inner sheath", "id": "GO:0160111", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160111", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GEK3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GEK3" } ], "pmid": "" } ], "molecular_function": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GEK3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GEK3" } ], "pmid": "" } ], "biological_process": [ { "name": "flagellated sperm motility", "id": "GO:0030317", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030317", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GEK3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GEK3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6GEK3-1", "start_pos": "441", "end_pos": "441", "site_lbl": "Thr441", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 441, "start_aa": "Thr", "end_pos": 441, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr441", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6GEK3-1" }, { "uniprot_canonical_ac": "A0A8I6APE1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6APE1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6APE1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1126, "chemical_mass": 123921.0, "gene_names": "Kiaa0319l;KIAA0319l;LOC100294508", "protein_name": "", "disease": [], "cellular_component": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6APE1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6APE1" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6APE1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6APE1" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6APE1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6APE1" } ], "pmid": "" }, { "name": "trans-Golgi network membrane", "id": "GO:0032588", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032588", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6APE1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6APE1" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6APE1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6APE1" } ], "pmid": "" } ], "biological_process": [ { "name": "neuron migration", "id": "GO:0001764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001764", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6APE1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6APE1" } ], "pmid": "" }, { "name": "response to auditory stimulus", "id": "GO:0010996", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010996", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6APE1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6APE1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6APE1-1" }, { "uniprot_canonical_ac": "A0A8I6A4X3-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A4X3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A4X3" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 430, "chemical_mass": 45409.0, "gene_names": "Selplg;Psgl1;Selplg;Selpl", "protein_name": "", "disease": [ { "disease_id": "DOID:3407", "name": "carotid artery disease", "description": "", "url": "https://disease-ontology.org/term/DOID:3407", "evidence": [ { "id": "3407", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3407" } ], "weight": 0.0 } ], "biological_process": [ { "name": "leukocyte adhesive activation", "id": "GO:0050902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050902", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A4X3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A4X3" } ], "pmid": "" }, { "name": "leukocyte migration", "id": "GO:0050900", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050900", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A4X3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A4X3" } ], "pmid": "" }, { "name": "leukocyte tethering or rolling", "id": "GO:0050901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050901", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A4X3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A4X3" } ], "pmid": "" }, { "name": "cellular response to interleukin-6", "id": "GO:0071354", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071354", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A4X3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A4X3" } ], "pmid": "" }, { "name": "positive regulation of hepatocyte apoptotic process", "id": "GO:1903945", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903945", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A4X3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A4X3" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A4X3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A4X3" } ], "pmid": "" }, { "name": "plasma membrane raft", "id": "GO:0044853", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044853", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A4X3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A4X3" } ], "pmid": "" }, { "name": "uropod", "id": "GO:0001931", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001931", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A4X3", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A4X3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6A4X3-1", "start_pos": "193", "end_pos": "193", "site_lbl": "Thr193", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 193, "start_aa": "Thr", "end_pos": 193, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr193", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I6A4X3-1", "start_pos": "213", "end_pos": "213", "site_lbl": "Thr213", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 213, "start_aa": "Thr", "end_pos": 213, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr213", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I6A4X3-1", "start_pos": "233", "end_pos": "233", "site_lbl": "Thr233", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 233, "start_aa": "Thr", "end_pos": 233, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr233", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I6A4X3-1", "start_pos": "243", "end_pos": "243", "site_lbl": "Thr243", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 243, "start_aa": "Thr", "end_pos": 243, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr243", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] }, { "uniprot_canonical_ac": "A0A8I6A4X3-1", "start_pos": "327", "end_pos": "327", "site_lbl": "Thr327", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 327, "start_aa": "Thr", "end_pos": 327, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr327", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6A4X3-1" }, { "uniprot_canonical_ac": "A0A8I5ZM64-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZM64", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZM64" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 531, "chemical_mass": 58279.0, "gene_names": "Rcbtb1;Rcbtb1", "protein_name": "RCC1 and BTB domain-containing protein 1", "disease": [ { "disease_id": "DOID:0080815", "name": "childhood-onset asthma", "description": "A chronic asthma that is characterized by first presentation in early childhood.", "url": "https://disease-ontology.org/term/DOID:0080815", "evidence": [ { "id": "0080815", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080815" } ], "weight": 0.0 }, { "disease_id": "DOID:1205", "name": "allergic disease", "description": "An immune system disease that is an exaggerated immune response to allergens, such as insect venom, dust mites, pollen, pet dander, drugs or some foods.", "url": "https://disease-ontology.org/term/DOID:1205", "evidence": [ { "id": "1205", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1205" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZM64", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZM64" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZM64", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZM64" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZM64", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZM64" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZM64", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZM64" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5ZM64-1" }, { "uniprot_canonical_ac": "A0A8I5ZXX2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZXX2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZXX2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1762, "chemical_mass": 191181.0, "gene_names": "Kdm3b;Kdm3b;LOC682469", "protein_name": "Lysine-specific demethylase", "disease": [ { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 }, { "disease_id": "DOID:9952", "name": "acute lymphoblastic leukemia", "description": "A acute leukemia that is characterized by over production of lymphoblasts.", "url": "https://disease-ontology.org/term/DOID:9952", "evidence": [ { "id": "9952", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9952" } ], "weight": 0.0 } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZXX2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZXX2" } ], "pmid": "" }, { "name": "demethylation", "id": "GO:0070988", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070988", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZXX2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZXX2" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZXX2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZXX2" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZXX2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZXX2" } ], "pmid": "" }, { "name": "histone H3K9me/H3K9me2 demethylase activity", "id": "GO:0140683", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140683", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZXX2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZXX2" } ], "pmid": "" }, { "name": "chromatin DNA binding", "id": "GO:0031490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031490", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZXX2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZXX2" } ], "pmid": "" }, { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZXX2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZXX2" } ], "pmid": "" }, { "name": "histone H3K9 demethylase activity", "id": "GO:0032454", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032454", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZXX2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZXX2" } ], "pmid": "" } ], "cellular_component": [ { "name": "histone deacetylase complex", "id": "GO:0000118", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000118", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZXX2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZXX2" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZXX2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZXX2" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZXX2", "url": "https://www.uniprot.org/uniprotkb/A0A8I5ZXX2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I5ZXX2-1", "start_pos": "1283", "end_pos": "1283", "site_lbl": "Thr1283", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1283, "start_aa": "Thr", "end_pos": 1283, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1283", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I5ZXX2-1" }, { "uniprot_canonical_ac": "A0A8I6AM45-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AM45", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AM45" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 402, "chemical_mass": 44685.0, "gene_names": "Gpr132", "protein_name": "", "disease": [ { "disease_id": "DOID:417", "name": "autoimmune disease", "description": "An immune system disease that is an overactive immune response of the body against substances and tissues normally present in the body resulting from an abnormal functioning of the immune system that results in the production of antibodies or T cell directed against the host tissues.", "url": "https://disease-ontology.org/term/DOID:417", "evidence": [ { "id": "417", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:417" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AM45", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AM45" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AM45", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AM45" } ], "pmid": "" } ], "biological_process": [ { "name": "G1/S transition of mitotic cell cycle", "id": "GO:0000082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000082", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AM45", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AM45" } ], "pmid": "" }, { "name": "negative regulation of G2/M transition of mitotic cell cycle", "id": "GO:0010972", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010972", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AM45", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AM45" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AM45-1" }, { "uniprot_canonical_ac": "A0A8I6AEL0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEL0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEL0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1381, "chemical_mass": 154783.0, "gene_names": "Map3k5;Ask1;Map3k5;RGD1306565", "protein_name": "mitogen-activated protein kinase kinase kinase", "disease": [ { "disease_id": "DOID:10976", "name": "membranous glomerulonephritis", "description": "", "url": "https://disease-ontology.org/term/DOID:10976", "evidence": [ { "id": "10976", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10976" } ], "weight": 0.0 }, { "disease_id": "DOID:12858", "name": "Huntington's disease", "description": "A neurodegenerative disease that has_material_basis_in autosomal dominant inheritance and is characterized by unwanted choreatic movements, behavioral and psychiatric disturbances and dementia and has_material_basis_in expansion of CAG triplet repeats (glutamine) resulting in neuron degeneration affecting muscle coordination, cognitive abilities.", "url": "https://disease-ontology.org/term/DOID:12858", "evidence": [ { "id": "12858", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12858" } ], "weight": 0.0 }, { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 }, { "disease_id": "DOID:224", "name": "transient cerebral ischemia", "description": "A brain ischemia that is characterized by ischemia of brief duration and without resultant tissue death.", "url": "https://disease-ontology.org/term/DOID:224", "evidence": [ { "id": "224", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:224" } ], "weight": 0.0 }, { "disease_id": "DOID:3526", "name": "cerebral infarction", "description": "A cerebrovascular disease that is characterized by an area of necrotic tissue in the brain resulting from a blockage or narrowing in the arteries supplying blood and oxygen to the brain.", "url": "https://disease-ontology.org/term/DOID:3526", "evidence": [ { "id": "3526", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3526" } ], "weight": 0.0 }, { "disease_id": "DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia.", "url": "https://disease-ontology.org/term/DOID:5844", "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ], "weight": 0.0 }, { "disease_id": "DOID:670", "name": "amphetamine abuse", "description": "A substance abuse that involves the recurring use of amphetamines despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:670", "evidence": [ { "id": "670", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:670" } ], "weight": 0.0 }, { "disease_id": "DOID:8677", "name": "perinatal necrotizing enterocolitis", "description": "", "url": "https://disease-ontology.org/term/DOID:8677", "evidence": [ { "id": "8677", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8677" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "IRE1-TRAF2-ASK1 complex", "id": "GO:1990604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990604", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEL0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEL0" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEL0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEL0" } ], "pmid": "" }, { "name": "protein kinase complex", "id": "GO:1902911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902911", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEL0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEL0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEL0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEL0" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEL0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEL0" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEL0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEL0" } ], "pmid": "" } ], "molecular_function": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEL0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEL0" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEL0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEL0" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEL0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEL0" } ], "pmid": "" }, { "name": "protein domain specific binding", "id": "GO:0019904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019904", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEL0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEL0" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEL0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEL0" } ], "pmid": "" }, { "name": "protein phosphatase binding", "id": "GO:0019903", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019903", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEL0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEL0" } ], "pmid": "" }, { "name": "JUN kinase kinase kinase activity", "id": "GO:0004706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004706", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEL0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEL0" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEL0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEL0" } ], "pmid": "" }, { "name": "MAP kinase kinase kinase activity", "id": "GO:0004709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004709", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEL0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEL0" } ], "pmid": "" }, { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEL0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEL0" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEL0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEL0" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEL0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEL0" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of apoptotic process", "id": "GO:0043065", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043065", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEL0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEL0" } ], "pmid": "" }, { "name": "positive regulation of JNK cascade", "id": "GO:0046330", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046330", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEL0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEL0" } ], "pmid": "" }, { "name": "JNK cascade", "id": "GO:0007254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007254", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEL0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEL0" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEL0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEL0" } ], "pmid": "" }, { "name": "cellular response to hydrogen peroxide", "id": "GO:0070301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070301", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEL0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEL0" } ], "pmid": "" }, { "name": "intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress", "id": "GO:0070059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070059", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEL0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEL0" } ], "pmid": "" }, { "name": "stress-activated MAPK cascade", "id": "GO:0051403", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051403", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEL0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEL0" } ], "pmid": "" }, { "name": "cellular response to amino acid starvation", "id": "GO:0034198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034198", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEL0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEL0" } ], "pmid": "" }, { "name": "positive regulation of myoblast differentiation", "id": "GO:0045663", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045663", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEL0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEL0" } ], "pmid": "" }, { "name": "p38MAPK cascade", "id": "GO:0038066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038066", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEL0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEL0" } ], "pmid": "" }, { "name": "neuron intrinsic apoptotic signaling pathway in response to oxidative stress", "id": "GO:0036480", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036480", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEL0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEL0" } ], "pmid": "" }, { "name": "positive regulation of protein phosphorylation", "id": "GO:0001934", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001934", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEL0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEL0" } ], "pmid": "" }, { "name": "response to ischemia", "id": "GO:0002931", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002931", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEL0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEL0" } ], "pmid": "" }, { "name": "positive regulation of MAPK cascade", "id": "GO:0043410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043410", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEL0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEL0" } ], "pmid": "" }, { "name": "neuron apoptotic process", "id": "GO:0051402", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051402", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEL0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEL0" } ], "pmid": "" }, { "name": "MAPK cascade", "id": "GO:0000165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000165", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEL0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEL0" } ], "pmid": "" }, { "name": "apoptotic signaling pathway", "id": "GO:0097190", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097190", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEL0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEL0" } ], "pmid": "" }, { "name": "positive regulation of vascular associated smooth muscle cell proliferation", "id": "GO:1904707", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904707", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEL0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEL0" } ], "pmid": "" }, { "name": "positive regulation of p38MAPK cascade", "id": "GO:1900745", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900745", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEL0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEL0" } ], "pmid": "" }, { "name": "cellular response to tumor necrosis factor", "id": "GO:0071356", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071356", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEL0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEL0" } ], "pmid": "" }, { "name": "positive regulation of cardiac muscle cell apoptotic process", "id": "GO:0010666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010666", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEL0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEL0" } ], "pmid": "" }, { "name": "response to endoplasmic reticulum stress", "id": "GO:0034976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034976", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEL0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEL0" } ], "pmid": "" }, { "name": "positive regulation of JUN kinase activity", "id": "GO:0043507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043507", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEL0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEL0" } ], "pmid": "" }, { "name": "programmed necrotic cell death", "id": "GO:0097300", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097300", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEL0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEL0" } ], "pmid": "" }, { "name": "regulation of programmed cell death", "id": "GO:0043067", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043067", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEL0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEL0" } ], "pmid": "" }, { "name": "intrinsic apoptotic signaling pathway in response to oxidative stress", "id": "GO:0008631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008631", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEL0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEL0" } ], "pmid": "" }, { "name": "endothelial cell apoptotic process", "id": "GO:0072577", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072577", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEL0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEL0" } ], "pmid": "" }, { "name": "cellular response to reactive nitrogen species", "id": "GO:1902170", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902170", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AEL0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AEL0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AEL0-1" }, { "uniprot_canonical_ac": "A0A0G2K1B1-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K1B1", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K1B1" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 177, "chemical_mass": 19145.0, "gene_names": "Zfp428;RGD1564862;Zfp428", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A0G2K1B1-1", "start_pos": "97", "end_pos": "97", "site_lbl": "Thr97", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 97, "start_aa": "Thr", "end_pos": 97, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr97", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A0G2K1B1-1" }, { "uniprot_canonical_ac": "A0A8I6G470-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G470", "url": "https://www.uniprot.org/uniprotkb/A0A8I6G470" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 689, "chemical_mass": 77495.0, "gene_names": "Kiaa1328;RGD1562608", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6G470-1", "start_pos": "382", "end_pos": "382", "site_lbl": "Thr382", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 382, "start_aa": "Thr", "end_pos": 382, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr382", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6G470-1" }, { "uniprot_canonical_ac": "A0A8I6ADE8-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ADE8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ADE8" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 474, "chemical_mass": 54175.0, "gene_names": "Sync", "protein_name": "", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ADE8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ADE8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ADE8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ADE8" } ], "pmid": "" }, { "name": "neuromuscular junction", "id": "GO:0031594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031594", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ADE8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ADE8" } ], "pmid": "" }, { "name": "intermediate filament", "id": "GO:0005882", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005882", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ADE8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ADE8" } ], "pmid": "" }, { "name": "sarcolemma", "id": "GO:0042383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042383", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ADE8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ADE8" } ], "pmid": "" }, { "name": "Z disc", "id": "GO:0030018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030018", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ADE8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ADE8" } ], "pmid": "" } ], "biological_process": [ { "name": "intermediate filament-based process", "id": "GO:0045103", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045103", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6ADE8", "url": "https://www.uniprot.org/uniprotkb/A0A8I6ADE8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6ADE8-1" }, { "uniprot_canonical_ac": "A0A8I6AD55-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AD55", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AD55" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 232, "chemical_mass": 27035.0, "gene_names": "Chchd3;Chchd3", "protein_name": "", "disease": [ { "disease_id": "DOID:9955", "name": "hypoplastic left heart syndrome", "description": "A congenital heart disease characterized by abnormal development of the left-sided structures of the heart.", "url": "https://disease-ontology.org/term/DOID:9955", "evidence": [ { "id": "9955", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9955" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "MICOS complex", "id": "GO:0061617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061617", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AD55", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AD55" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AD55", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AD55" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AD55", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AD55" } ], "pmid": "" } ], "molecular_function": [ { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AD55", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AD55" } ], "pmid": "" }, { "name": "phosphatase binding", "id": "GO:0019902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019902", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AD55", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AD55" } ], "pmid": "" } ], "biological_process": [ { "name": "mitochondrial fusion", "id": "GO:0008053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008053", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AD55", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AD55" } ], "pmid": "" }, { "name": "cristae formation", "id": "GO:0042407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042407", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AD55", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AD55" } ], "pmid": "" }, { "name": "inner mitochondrial membrane organization", "id": "GO:0007007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007007", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AD55", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AD55" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6AD55-1", "start_pos": "29", "end_pos": "29", "site_lbl": "Ser29", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 29, "start_aa": "Ser", "end_pos": 29, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser29", "evidence": [ { "id": "27213235", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/27213235" }, { "id": "A0A8I6AD55", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A0A8I6AD55" }, { "id": "26446791", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/26446791" }, { "id": "A0A8I6AD55", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/A0A8I6AD55" } ] } ] } ], "record_id": "A0A8I6AD55-1" }, { "uniprot_canonical_ac": "A0A8I6GI34-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI34", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI34" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 1144, "chemical_mass": 130588.0, "gene_names": "Snx13;Snx13", "protein_name": "Sorting nexin-13", "disease": [ { "disease_id": "DOID:0080066", "name": "autosomal recessive spinocerebellar ataxia 20", "description": "An autosomal recessive cerebellar ataxia that is characterized by severely delayed psychomotor development with poor or absent speech, wide-based or absent gait, coarse facies, and cerebellar atrophy and that has_material_basis_in homozygous mutation in the SNX14 gene on chromosome 6q14.", "url": "https://disease-ontology.org/term/DOID:0080066", "evidence": [ { "id": "0080066", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080066" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI34", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI34" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI34", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI34" } ], "pmid": "" }, { "name": "positive regulation of GTPase activity", "id": "GO:0043547", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043547", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI34", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI34" } ], "pmid": "" } ], "molecular_function": [ { "name": "phosphatidylinositol-3-phosphate binding", "id": "GO:0032266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032266", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI34", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI34" } ], "pmid": "" }, { "name": "phosphatidylinositol binding", "id": "GO:0035091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035091", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GI34", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GI34" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8I6GI34-1", "start_pos": "654", "end_pos": "654", "site_lbl": "Thr654", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 654, "start_aa": "Thr", "end_pos": 654, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr654", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ] } ] } ], "record_id": "A0A8I6GI34-1" }, { "uniprot_canonical_ac": "A0A8I6GDI7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GDI7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GDI7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 597, "chemical_mass": 67294.0, "gene_names": "Rfx8;Rfx8", "protein_name": "DNA-binding protein RFX8", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GDI7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GDI7" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GDI7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GDI7" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GDI7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GDI7" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GDI7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GDI7" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GDI7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GDI7" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GDI7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GDI7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6GDI7-1" }, { "uniprot_canonical_ac": "A0A8I5Y545-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y545", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y545" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 497, "chemical_mass": 53034.0, "gene_names": "Zfp385b;Zfp385b;Zfp533", "protein_name": "Zinc finger protein 385B", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y545", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y545" } ], "pmid": "" }, { "name": "fibrillar center", "id": "GO:0001650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001650", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y545", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y545" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y545", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y545" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y545", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y545" } ], "pmid": "" }, { "name": "p53 binding", "id": "GO:0002039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002039", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y545", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y545" } ], "pmid": "" } ], "biological_process": [ { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y545", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y545" } ], "pmid": "" }, { "name": "intrinsic apoptotic signaling pathway by p53 class mediator", "id": "GO:0072332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072332", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5Y545", "url": "https://www.uniprot.org/uniprotkb/A0A8I5Y545" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I5Y545-1" }, { "uniprot_canonical_ac": "A0A8I6AVP7-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AVP7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AVP7" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 447, "chemical_mass": 50064.0, "gene_names": "Odr4;Odr4;RGD1307830", "protein_name": "Protein odr-4 homolog", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AVP7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AVP7" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular protein localization", "id": "GO:0008104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008104", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6AVP7", "url": "https://www.uniprot.org/uniprotkb/A0A8I6AVP7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6AVP7-1" }, { "uniprot_canonical_ac": "A0A8I6GLF0-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GLF0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GLF0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 760, "chemical_mass": 86271.0, "gene_names": "Zyg11a;Zyg11a", "protein_name": "", "disease": [], "cellular_component": [ { "name": "Cul2-RING ubiquitin ligase complex", "id": "GO:0031462", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031462", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6GLF0", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GLF0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6GLF0-1" }, { "uniprot_canonical_ac": "A0A8I6A1C2-1", "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1C2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1C2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "length": 537, "chemical_mass": 61625.0, "gene_names": "Il18r1;Il18r1", "protein_name": "Interleukin-18 receptor 1", "disease": [ { "disease_id": "DOID:13406", "name": "pulmonary sarcoidosis", "description": "A sarcoidosis that is characterized by noncaseating granulomatous infiltration of the lungs and supporting lymph nodes, bilateral hilar adenopathy, and pulmonary issues, has_symptom shortness of breath, fatigue, wheezing, and chronic cough, and develops_from a type IV hypersensitivity reaction.", "url": "https://disease-ontology.org/term/DOID:13406", "evidence": [ { "id": "13406", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13406" } ], "weight": 0.0 }, { "disease_id": "DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.", "url": "https://disease-ontology.org/term/DOID:2841", "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ], "weight": 0.0 }, { "disease_id": "DOID:3770", "name": "pulmonary fibrosis", "description": "An interstitial lung disease that is characterized by destruction, scarring, and thickening of the interstitial lung tissues and progressive pulmonary function loss in a restrictive pattern, has_symptom progressive shortness of breath, fatigue, and chronic cough, possibly has_material_basis_in exposure to certain chemicals, autoimmune conditions, and radiation. It can be caused by inhaling hazardous chemicals, certain diseases, medication and genetics or unknown causes.", "url": "https://disease-ontology.org/term/DOID:3770", "evidence": [ { "id": "3770", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3770" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:850", "name": "lung disease", "description": "A lower respiratory tract disease in which the function of the lungs is adversely affected by narrowing or blockage of the airways resulting in poor air flow, a loss of elasticity in the lungs that produces a decrease in the total volume of air that the lungs are able to hold, and clotting, scarring, or inflammation of the blood vessels that affect the ability of the lungs to take up oxygen and to release carbon dioxide.", "url": "https://disease-ontology.org/term/DOID:850", "evidence": [ { "id": "850", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:850" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1C2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1C2" } ], "pmid": "" }, { "name": "interleukin-18 receptor complex", "id": "GO:0045092", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045092", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1C2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1C2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1C2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1C2" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1C2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1C2" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of cold-induced thermogenesis", "id": "GO:0120163", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120163", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1C2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1C2" } ], "pmid": "" }, { "name": "T-helper 1 cell differentiation", "id": "GO:0045063", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045063", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1C2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1C2" } ], "pmid": "" }, { "name": "inflammatory response", "id": "GO:0006954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006954", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1C2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1C2" } ], "pmid": "" }, { "name": "positive regulation of non-canonical NF-kappaB signal transduction", "id": "GO:1901224", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901224", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1C2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1C2" } ], "pmid": "" }, { "name": "adaptive immune response", "id": "GO:0002250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002250", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1C2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1C2" } ], "pmid": "" }, { "name": "positive regulation of type II interferon production", "id": "GO:0032729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032729", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1C2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1C2" } ], "pmid": "" }, { "name": "interleukin-18-mediated signaling pathway", "id": "GO:0035655", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035655", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1C2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1C2" } ], "pmid": "" }, { "name": "natural killer cell activation", "id": "GO:0030101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030101", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1C2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1C2" } ], "pmid": "" }, { "name": "positive regulation of T-helper 1 cell cytokine production", "id": "GO:2000556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000556", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1C2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1C2" } ], "pmid": "" } ], "molecular_function": [ { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1C2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1C2" } ], "pmid": "" }, { "name": "interleukin-18 binding", "id": "GO:0042007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042007", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1C2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1C2" } ], "pmid": "" }, { "name": "interleukin-18 receptor activity", "id": "GO:0042008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042008", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6A1C2", "url": "https://www.uniprot.org/uniprotkb/A0A8I6A1C2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A8I6A1C2-1" } ]