{
    "disease_id": "DOID:0111914",
    "recommended_name": {
        "id": "DOID:0111914",
        "resource": "Disease Ontology",
        "url": "https://disease-ontology.org/term/DOID:0111914",
        "name": "spermatogenic failure 35",
        "description": "A spermatogenic failure characterized by multiple morphologic abnormalities of the flagella resulting in severely impaired sperm motility and infertility that has_material_basis_in homozygous or compound heterozygous mutation in the QRICH2 gene on chromosome 17q25.1."
    },
    "synonyms": [
        {
            "id": "DOID:0111914",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0111914",
            "name": "SPGF35",
            "description": ""
        },
        {
            "id": "MONDO:0032686",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0032686",
            "name": "spermatogenic failure 35",
            "description": ""
        },
        {
            "id": "MONDO:0032686",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0032686",
            "name": "SPGF35",
            "description": ""
        },
        {
            "id": "MIM:618341",
            "resource": "MIM",
            "url": "https://www.omim.org/entry/618341",
            "name": "Spermatogenic failure 35",
            "description": "Spermatogenic failure 35"
        }
    ],
    "children": [],
    "id_list": [
        "DOID:0111914"
    ],
    "unlinked_id_list": [],
    "crossref": [
        {
            "id": "DOID:0111914",
            "database": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0111914",
            "categories": []
        },
        {
            "id": "MONDO:0032686",
            "database": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0032686",
            "categories": []
        },
        {
            "id": "MIM:618341",
            "database": "MIM",
            "url": "https://www.omim.org/entry/618341",
            "categories": []
        }
    ],
    "proteins": [
        {
            "uniprot_canonical_ac": "Q3V2A7-1",
            "uniprot_ac": "Q3V2A7",
            "uniprot_id": "QRIC2_MOUSE",
            "refseq_ac": "NP_001028439",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
                {
                    "name": "Glutamine-rich protein 2",
                    "type": "recommended"
                },
                {
                    "name": "glutamine-rich protein 2",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Qrich2",
                    "type": "recommended"
                },
                {
                    "name": "Gm66",
                    "type": "synonym"
                },
                {
                    "name": "Qrich2",
                    "type": "synonym"
                }
            ],
            "record_id": "Q3V2A7-1",
            "evidence": [
                {
                    "id": "0111914",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0111914"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q9H0J4-1",
            "uniprot_ac": "Q9H0J4",
            "uniprot_id": "QRIC2_HUMAN",
            "refseq_ac": "NP_115510",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Glutamine-rich protein 2",
                    "type": "recommended"
                },
                {
                    "name": "glutamine-rich protein 2 isoform 1",
                    "type": "synonym"
                },
                {
                    "name": "glutamine-rich protein 2",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "QRICH2",
                    "type": "recommended"
                },
                {
                    "name": "QRICH2",
                    "type": "synonym"
                },
                {
                    "name": "SPGF35",
                    "type": "synonym"
                }
            ],
            "record_id": "Q9H0J4-1",
            "evidence": [
                {
                    "id": "618341",
                    "database": "MIM",
                    "url": "https://www.omim.org/entry/618341"
                },
                {
                    "id": "0111914",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0111914"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "A0ABK0M777-1",
            "uniprot_ac": "A0ABK0M777",
            "uniprot_id": "A0ABK0M777_RAT",
            "refseq_ac": "NP_001403824",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
            "protein_names": [
                {
                    "name": "Glutamine rich 2",
                    "type": "synonym"
                },
                {
                    "name": "glutamine-rich protein 2-like",
                    "type": "synonym"
                },
                {
                    "name": "glutamine-rich protein 2",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Qrich2",
                    "type": "recommended"
                },
                {
                    "name": "Qrich2",
                    "type": "synonym"
                },
                {
                    "name": "RGD1562974",
                    "type": "synonym"
                }
            ],
            "record_id": "A0ABK0M777-1",
            "evidence": [
                {
                    "id": "0111914",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0111914"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q9VQ22-1",
            "uniprot_ac": "Q9VQ22",
            "uniprot_id": "Q9VQ22_DROME",
            "refseq_ac": "NP_608605",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Drosophila melanogaster",
                    "taxid": 7227,
                    "common_name": "Fruit fly",
                    "glygen_name": "Fruit fly",
                    "reference_species": "Drosophila melanogaster [7227]"
                }
            ],
            "protein_names": [
                {
                    "name": "CG10869-PA",
                    "type": "synonym"
                },
                {
                    "name": "No individualized sperm",
                    "type": "synonym"
                },
                {
                    "name": "nis-PA",
                    "type": "synonym"
                },
                {
                    "name": "no individualized sperm",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "nis",
                    "type": "recommended"
                },
                {
                    "name": "CG10869",
                    "type": "synonym"
                },
                {
                    "name": "Dmel\\CG10869",
                    "type": "synonym"
                },
                {
                    "name": "Dmel_CG10869",
                    "type": "synonym"
                },
                {
                    "name": "nis",
                    "type": "synonym"
                }
            ],
            "record_id": "Q9VQ22-1",
            "evidence": [
                {
                    "id": "0111914",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0111914"
                }
            ]
        }
    ],
    "glycans": [],
    "biomarkers": [],
    "association_flag": "1000",
    "record_id": "doid.0111914"
}