{
    "disease_id": "DOID:0090026",
    "recommended_name": {
        "id": "DOID:0090026",
        "resource": "Disease Ontology",
        "url": "https://disease-ontology.org/term/DOID:0090026",
        "name": "split hand-foot malformation 6",
        "description": "A split-hand/foot malformation that has_material_basis_in homozygous mutation in the WNT10B gene on chromosome 12q13."
    },
    "synonyms": [
        {
            "id": "DOID:0090026",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0090026",
            "name": "SHFM6",
            "description": ""
        },
        {
            "id": "MONDO:0009157",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0009157",
            "name": "split hand-foot malformation 6",
            "description": "Any split hand-foot malformation in which the cause of the disease is a mutation in the WNT10B gene."
        },
        {
            "id": "MONDO:0009157",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0009157",
            "name": "SHFM6",
            "description": ""
        },
        {
            "id": "MONDO:0009157",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0009157",
            "name": "WNT10B split hand-foot malformation",
            "description": ""
        },
        {
            "id": "MONDO:0009157",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0009157",
            "name": "split hand-foot malformation caused by mutation in WNT10B",
            "description": ""
        },
        {
            "id": "MONDO:0009157",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0009157",
            "name": "split hand-foot malformation type 6",
            "description": ""
        },
        {
            "id": "MONDO:0009157",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0009157",
            "name": "split-hand/foot malformation type 6",
            "description": ""
        },
        {
            "id": "MONDO:0009157",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0009157",
            "name": "split-hand/foot malformation 6",
            "description": ""
        },
        {
            "id": "MIM:225300",
            "resource": "MIM",
            "url": "https://www.omim.org/entry/225300",
            "name": "Split-hand/foot malformation 6",
            "description": "Split-hand/foot malformation 6"
        }
    ],
    "children": [],
    "id_list": [
        "DOID:0090026"
    ],
    "unlinked_id_list": [],
    "crossref": [
        {
            "id": "DOID:0090026",
            "database": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0090026",
            "categories": []
        },
        {
            "id": "MONDO:0009157",
            "database": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0009157",
            "categories": []
        },
        {
            "id": "MIM:225300",
            "database": "MIM",
            "url": "https://www.omim.org/entry/225300",
            "categories": []
        }
    ],
    "proteins": [
        {
            "uniprot_canonical_ac": "Q801F7-1",
            "uniprot_ac": "Q801F7",
            "uniprot_id": "WN10B_DANRE",
            "refseq_ac": "NP_835737",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Danio rerio",
                    "taxid": 7955,
                    "common_name": "Zebrafish",
                    "glygen_name": "Zebrafish",
                    "reference_species": "Danio rerio [7955]"
                }
            ],
            "protein_names": [
                {
                    "name": "Protein Wnt-10b",
                    "type": "recommended"
                },
                {
                    "name": "protein Wnt-10b precursor",
                    "type": "synonym"
                },
                {
                    "name": "protein Wnt-10b",
                    "type": "synonym"
                },
                {
                    "name": "wnt-d",
                    "type": "synonym"
                },
                {
                    "name": "wnt10b-related",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "wnt10b",
                    "type": "recommended"
                },
                {
                    "name": "Zwnt[d]",
                    "type": "synonym"
                },
                {
                    "name": "wnt10br",
                    "type": "synonym"
                },
                {
                    "name": "wnt10b",
                    "type": "synonym"
                },
                {
                    "name": "wnt[d]",
                    "type": "synonym"
                }
            ],
            "record_id": "Q801F7-1",
            "evidence": [
                {
                    "id": "0090026",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0090026"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P48614-1",
            "uniprot_ac": "P48614",
            "uniprot_id": "WN10B_MOUSE",
            "refseq_ac": "NP_035848",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
                {
                    "name": "Protein Wnt-10b",
                    "type": "recommended"
                },
                {
                    "name": "Protein Wnt-12",
                    "type": "synonym"
                },
                {
                    "name": "protein Wnt-10b precursor",
                    "type": "synonym"
                },
                {
                    "name": "protein Wnt-10b",
                    "type": "synonym"
                },
                {
                    "name": "wingless related MMTV integration site 10b",
                    "type": "synonym"
                },
                {
                    "name": "wnt-12",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Wnt10b",
                    "type": "recommended"
                },
                {
                    "name": "Wnt-10b",
                    "type": "synonym"
                },
                {
                    "name": "Wnt10b",
                    "type": "synonym"
                },
                {
                    "name": "Wnt10",
                    "type": "synonym"
                },
                {
                    "name": "Wnt12",
                    "type": "synonym"
                }
            ],
            "record_id": "P48614-1",
            "evidence": [
                {
                    "id": "0090026",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0090026"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "O00744-1",
            "uniprot_ac": "O00744",
            "uniprot_id": "WN10B_HUMAN",
            "refseq_ac": "NP_003385",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Protein Wnt-10b",
                    "type": "recommended"
                },
                {
                    "name": "Protein Wnt-12",
                    "type": "synonym"
                },
                {
                    "name": "WNT-10B protein",
                    "type": "synonym"
                },
                {
                    "name": "protein Wnt-10b precursor",
                    "type": "synonym"
                },
                {
                    "name": "protein Wnt-10b",
                    "type": "synonym"
                },
                {
                    "name": "wingless-type MMTV integration site family, member 10B",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "WNT10B",
                    "type": "recommended"
                },
                {
                    "name": "SHFM6",
                    "type": "synonym"
                },
                {
                    "name": "STHAG8",
                    "type": "synonym"
                },
                {
                    "name": "WNT-12",
                    "type": "synonym"
                },
                {
                    "name": "WNT10B",
                    "type": "synonym"
                },
                {
                    "name": "WNT12",
                    "type": "synonym"
                }
            ],
            "record_id": "O00744-1",
            "evidence": [
                {
                    "id": "225300",
                    "database": "MIM",
                    "url": "https://www.omim.org/entry/225300"
                },
                {
                    "id": "0090026",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0090026"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "A0A0G2K6Q8-1",
            "uniprot_ac": "A0A0G2K6Q8",
            "uniprot_id": "A0A0G2K6Q8_RAT",
            "refseq_ac": "NP_001101581",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
            "protein_names": [
                {
                    "name": "Protein Wnt",
                    "type": "recommended"
                },
                {
                    "name": "protein Wnt-10b precursor",
                    "type": "synonym"
                },
                {
                    "name": "protein Wnt-10b",
                    "type": "synonym"
                },
                {
                    "name": "wingless related MMTV integration site 10b",
                    "type": "synonym"
                },
                {
                    "name": "wingless-type MMTV integration site family, member 10B",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Wnt10b",
                    "type": "recommended"
                },
                {
                    "name": "Wnt10b",
                    "type": "synonym"
                }
            ],
            "record_id": "A0A0G2K6Q8-1",
            "evidence": [
                {
                    "id": "0090026",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0090026"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q9VM25-1",
            "uniprot_ac": "Q9VM25",
            "uniprot_id": "Q9VM25_DROME",
            "refseq_ac": "NP_609109",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Drosophila melanogaster",
                    "taxid": 7227,
                    "common_name": "Fruit fly",
                    "glygen_name": "Fruit fly",
                    "reference_species": "Drosophila melanogaster [7227]"
                }
            ],
            "protein_names": [
                {
                    "name": "Protein Wnt",
                    "type": "recommended"
                },
                {
                    "name": "CG4971-PC",
                    "type": "synonym"
                },
                {
                    "name": "Wnt oncogene analog 10",
                    "type": "synonym"
                },
                {
                    "name": "Wnt10-PC",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Wnt10",
                    "type": "recommended"
                },
                {
                    "name": "CG4971",
                    "type": "synonym"
                },
                {
                    "name": "D-Wnt-10",
                    "type": "synonym"
                },
                {
                    "name": "DWnt-10",
                    "type": "synonym"
                },
                {
                    "name": "DWnt10",
                    "type": "synonym"
                },
                {
                    "name": "Dm DWnt10",
                    "type": "synonym"
                },
                {
                    "name": "Dmel\\CG4971",
                    "type": "synonym"
                },
                {
                    "name": "Dmel_CG4971",
                    "type": "synonym"
                },
                {
                    "name": "Dwnt-10",
                    "type": "synonym"
                },
                {
                    "name": "Dwnt10",
                    "type": "synonym"
                },
                {
                    "name": "Wnt10",
                    "type": "synonym"
                },
                {
                    "name": "wnt10",
                    "type": "synonym"
                }
            ],
            "record_id": "Q9VM25-1",
            "evidence": [
                {
                    "id": "0090026",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0090026"
                }
            ]
        }
    ],
    "glycans": [],
    "biomarkers": [],
    "association_flag": "1000",
    "record_id": "doid.0090026"
}