{
    "disease_id": "DOID:0080839",
    "recommended_name": {
        "id": "DOID:0080839",
        "resource": "Disease Ontology",
        "url": "https://disease-ontology.org/term/DOID:0080839",
        "name": "X-linked warfarin sensitivity",
        "description": "An inherited metabolic disorder that is characterized by bleeding complications when given warfarin for anticoagulation and that has_material_basis_in variation in the F9 gene on chromosome Xq27."
    },
    "synonyms": [
        {
            "id": "MONDO:0026768",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0026768",
            "name": "obsolete warfarin sensitivity, X-linked",
            "description": ""
        },
        {
            "id": "MONDO:0026768",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0026768",
            "name": "Warfarin sensitivity",
            "description": ""
        },
        {
            "id": "MIM:301052",
            "resource": "MIM",
            "url": "https://www.omim.org/entry/301052",
            "name": "Warfarin sensitivity, X-linked",
            "description": "Warfarin sensitivity, X-linked"
        }
    ],
    "children": [],
    "id_list": [
        "DOID:0080839"
    ],
    "unlinked_id_list": [],
    "crossref": [
        {
            "id": "DOID:0080839",
            "database": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0080839",
            "categories": []
        },
        {
            "id": "MONDO:0026768",
            "database": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0026768",
            "categories": []
        },
        {
            "id": "MIM:301052",
            "database": "MIM",
            "url": "https://www.omim.org/entry/301052",
            "categories": []
        }
    ],
    "proteins": [
        {
            "uniprot_canonical_ac": "E7F301-1",
            "uniprot_ac": "E7F301",
            "uniprot_id": "E7F301_DANRE",
            "refseq_ac": "",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Danio rerio",
                    "taxid": 7955,
                    "common_name": "Zebrafish",
                    "glygen_name": "Zebrafish",
                    "reference_species": "Danio rerio [7955]"
                }
            ],
            "protein_names": [
                {
                    "name": "Coagulation factor IX",
                    "type": "recommended"
                },
                {
                    "name": "3.4.21.22",
                    "type": "synonym"
                },
                {
                    "name": "3.4.21.6",
                    "type": "synonym"
                },
                {
                    "name": "Christmas factor",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "f9a",
                    "type": "recommended"
                },
                {
                    "name": "f9",
                    "type": "synonym"
                },
                {
                    "name": "zgc:109775",
                    "type": "synonym"
                }
            ],
            "record_id": "E7F301-1",
            "evidence": [
                {
                    "id": "0080839",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080839"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P16294-1",
            "uniprot_ac": "P16294",
            "uniprot_id": "FA9_MOUSE",
            "refseq_ac": "NP_001292726",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
                {
                    "name": "Coagulation factor IX",
                    "type": "recommended"
                },
                {
                    "name": "3.4.21.22",
                    "type": "synonym"
                },
                {
                    "name": "Christmas factor",
                    "type": "synonym"
                },
                {
                    "name": "christmas factor",
                    "type": "synonym"
                },
                {
                    "name": "coagulation factor IX isoform 2 precursor",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "F9",
                    "type": "recommended"
                },
                {
                    "name": "Cf-9",
                    "type": "synonym"
                },
                {
                    "name": "Cf9",
                    "type": "synonym"
                },
                {
                    "name": "F9",
                    "type": "synonym"
                }
            ],
            "record_id": "P16294-1",
            "evidence": [
                {
                    "id": "0080839",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080839"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P00740-1",
            "uniprot_ac": "P00740",
            "uniprot_id": "FA9_HUMAN",
            "refseq_ac": "NP_000124",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Coagulation factor IX",
                    "type": "recommended"
                },
                {
                    "name": "3.4.21.22",
                    "type": "synonym"
                },
                {
                    "name": "Christmas factor",
                    "type": "synonym"
                },
                {
                    "name": "PTC",
                    "type": "synonym"
                },
                {
                    "name": "Plasma thromboplastin component",
                    "type": "synonym"
                },
                {
                    "name": "coagulation factor IX isoform 1 preproprotein",
                    "type": "synonym"
                },
                {
                    "name": "factor 9",
                    "type": "synonym"
                },
                {
                    "name": "factor IX F9",
                    "type": "synonym"
                },
                {
                    "name": "plasma thromboplastic component",
                    "type": "synonym"
                },
                {
                    "name": "plasma thromboplastin component",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "F9",
                    "type": "recommended"
                },
                {
                    "name": "F9 p22",
                    "type": "synonym"
                },
                {
                    "name": "F9",
                    "type": "synonym"
                },
                {
                    "name": "FIX",
                    "type": "synonym"
                },
                {
                    "name": "HEMB",
                    "type": "synonym"
                },
                {
                    "name": "P19",
                    "type": "synonym"
                },
                {
                    "name": "PTC",
                    "type": "synonym"
                },
                {
                    "name": "THPH8",
                    "type": "synonym"
                }
            ],
            "record_id": "P00740-1",
            "evidence": [
                {
                    "id": "301052",
                    "database": "MIM",
                    "url": "https://www.omim.org/entry/301052"
                },
                {
                    "id": "0080839",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080839"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P16296-1",
            "uniprot_ac": "P16296",
            "uniprot_id": "FA9_RAT",
            "refseq_ac": "NP_113728",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
            "protein_names": [
                {
                    "name": "Coagulation factor IX",
                    "type": "recommended"
                },
                {
                    "name": "3.4.21.22",
                    "type": "synonym"
                },
                {
                    "name": "Christmas factor",
                    "type": "synonym"
                },
                {
                    "name": "Coagulation factor IX (plasma thromboplastic component, Christmas disease, hemophilia B)",
                    "type": "synonym"
                },
                {
                    "name": "christmas factor",
                    "type": "synonym"
                },
                {
                    "name": "coagulation factor 9",
                    "type": "synonym"
                },
                {
                    "name": "coagulation factor IX precursor",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "F9",
                    "type": "recommended"
                },
                {
                    "name": "Cf9",
                    "type": "synonym"
                },
                {
                    "name": "F9",
                    "type": "synonym"
                }
            ],
            "record_id": "P16296-1",
            "evidence": [
                {
                    "id": "0080839",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080839"
                }
            ]
        }
    ],
    "glycans": [],
    "biomarkers": [],
    "association_flag": "1000",
    "record_id": "doid.0080839"
}