{
    "disease_id": "DOID:0080763",
    "recommended_name": {
        "id": "DOID:0080763",
        "resource": "Disease Ontology",
        "url": "https://disease-ontology.org/term/DOID:0080763",
        "name": "diffuse gastric cancer",
        "description": "A stomach cancer that is characterized by development of diffuse (signet ring cell) gastric cancer underneath the stomach lining."
    },
    "synonyms": [],
    "children": [
        {
            "id": "DOID:0080764",
            "label": "hereditary diffuse gastric cancer",
            "link_status": true,
            "children": []
        }
    ],
    "id_list": [
        "DOID:0080764",
        "DOID:0080763"
    ],
    "unlinked_id_list": [],
    "crossref": [
        {
            "id": "DOID:0080763",
            "database": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0080763",
            "categories": []
        }
    ],
    "proteins": [
        {
            "uniprot_canonical_ac": "A0A8M2B1Q9-1",
            "uniprot_ac": "A0A8M2B1Q9",
            "uniprot_id": "A0A8M2B1Q9_DANRE",
            "refseq_ac": "XP_005155564",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Danio rerio",
                    "taxid": 7955,
                    "common_name": "Zebrafish",
                    "glygen_name": "Zebrafish",
                    "reference_species": "Danio rerio [7955]"
                }
            ],
            "protein_names": [
                {
                    "name": "Mitogen-activated protein kinase kinase kinase 1",
                    "type": "recommended"
                },
                {
                    "name": "MAPK/ERK kinase kinase 1",
                    "type": "synonym"
                },
                {
                    "name": "mitogen-activated protein kinase kinase kinase 1 isoform X1",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "map3k1",
                    "type": "recommended"
                },
                {
                    "name": "map3k1",
                    "type": "synonym"
                }
            ],
            "record_id": "A0A8M2B1Q9-1",
            "evidence": [
                {
                    "id": "0080763",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080763"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P53349-1",
            "uniprot_ac": "P53349",
            "uniprot_id": "M3K1_MOUSE",
            "refseq_ac": "",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
                {
                    "name": "Mitogen-activated protein kinase kinase kinase 1",
                    "type": "recommended"
                },
                {
                    "name": "2.7.11.25",
                    "type": "synonym"
                },
                {
                    "name": "MAPK/ERK kinase kinase 1",
                    "type": "synonym"
                },
                {
                    "name": "MEK kinase 1",
                    "type": "synonym"
                },
                {
                    "name": "MEKK 1",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Map3k1",
                    "type": "recommended"
                },
                {
                    "name": "Mekk1",
                    "type": "synonym"
                },
                {
                    "name": "Mekk",
                    "type": "synonym"
                }
            ],
            "record_id": "P53349-1",
            "evidence": [
                {
                    "id": "0080763",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080763"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P27636-1",
            "uniprot_ac": "P27636",
            "uniprot_id": "CDC15_YEAST",
            "refseq_ac": "NP_009411",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Saccharomyces cerevisiae S288C",
                    "taxid": 559292,
                    "common_name": "Baker's yeast",
                    "glygen_name": "Yeast",
                    "reference_species": "Saccharomyces cerevisiae S288C [559292]"
                }
            ],
            "protein_names": [
                {
                    "name": "Cell division control protein 15",
                    "type": "recommended"
                },
                {
                    "name": "2.7.11.1",
                    "type": "synonym"
                },
                {
                    "name": "serine/threonine protein kinase CDC15",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "CDC15",
                    "type": "recommended"
                },
                {
                    "name": "CDC15",
                    "type": "synonym"
                },
                {
                    "name": "LYT1",
                    "type": "synonym"
                },
                {
                    "name": "RLT1",
                    "type": "synonym"
                }
            ],
            "record_id": "P27636-1",
            "evidence": [
                {
                    "id": "0080763",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080763"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q62925-1",
            "uniprot_ac": "Q62925",
            "uniprot_id": "M3K1_RAT",
            "refseq_ac": "NP_446339",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
            "protein_names": [
                {
                    "name": "Mitogen-activated protein kinase kinase kinase 1",
                    "type": "recommended"
                },
                {
                    "name": "2.7.11.25",
                    "type": "synonym"
                },
                {
                    "name": "MAPK/ERK kinase kinase 1",
                    "type": "synonym"
                },
                {
                    "name": "MEK kinase 1",
                    "type": "synonym"
                },
                {
                    "name": "MEKK 1",
                    "type": "synonym"
                },
                {
                    "name": "mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase",
                    "type": "synonym"
                },
                {
                    "name": "mitogen-activated protein kinase kinase kinase 1",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Map3k1",
                    "type": "recommended"
                },
                {
                    "name": "Map3k1",
                    "type": "synonym"
                },
                {
                    "name": "Mekk1",
                    "type": "synonym"
                },
                {
                    "name": "Mekk",
                    "type": "synonym"
                }
            ],
            "record_id": "Q62925-1",
            "evidence": [
                {
                    "id": "0080763",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080763"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q13233-1",
            "uniprot_ac": "Q13233",
            "uniprot_id": "M3K1_HUMAN",
            "refseq_ac": "NP_005912",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Mitogen-activated protein kinase kinase kinase 1",
                    "type": "recommended"
                },
                {
                    "name": "2.3.2.27",
                    "type": "synonym"
                },
                {
                    "name": "2.7.11.25",
                    "type": "synonym"
                },
                {
                    "name": "MAP/ERK kinase kinase 1",
                    "type": "synonym"
                },
                {
                    "name": "MAPK/ERK kinase kinase 1",
                    "type": "synonym"
                },
                {
                    "name": "MEK kinase 1",
                    "type": "synonym"
                },
                {
                    "name": "MEKK 1",
                    "type": "synonym"
                },
                {
                    "name": "mitogen-activated protein kinase kinase kinase 1 isoform 1",
                    "type": "synonym"
                },
                {
                    "name": "mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "MAP3K1",
                    "type": "recommended"
                },
                {
                    "name": "MAP3K1",
                    "type": "synonym"
                },
                {
                    "name": "MAPKKK1",
                    "type": "synonym"
                },
                {
                    "name": "MEKK 1",
                    "type": "synonym"
                },
                {
                    "name": "MEKK1",
                    "type": "synonym"
                },
                {
                    "name": "MEKK",
                    "type": "synonym"
                },
                {
                    "name": "SRXY6",
                    "type": "synonym"
                }
            ],
            "record_id": "Q13233-1",
            "evidence": [
                {
                    "id": "0080763",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080763"
                }
            ]
        }
    ],
    "glycans": [],
    "biomarkers": [],
    "association_flag": "1000",
    "record_id": "doid.0080763"
}