{
    "disease_id": "DOID:0080641",
    "recommended_name": {
        "id": "DOID:0080641",
        "resource": "Disease Ontology",
        "url": "https://disease-ontology.org/term/DOID:0080641",
        "name": "tongue carcinoma",
        "description": "A tongue cancer that derives_from epithelial cells that cover the surface of the tongue."
    },
    "synonyms": [],
    "children": [],
    "id_list": [
        "DOID:0080641"
    ],
    "unlinked_id_list": [],
    "crossref": [
        {
            "id": "DOID:0080641",
            "database": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0080641",
            "categories": []
        }
    ],
    "proteins": [
        {
            "uniprot_canonical_ac": "F1Q636-1",
            "uniprot_ac": "F1Q636",
            "uniprot_id": "F1Q636_DANRE",
            "refseq_ac": "XP_005160972",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Danio rerio",
                    "taxid": 7955,
                    "common_name": "Zebrafish",
                    "glygen_name": "Zebrafish",
                    "reference_species": "Danio rerio [7955]"
                }
            ],
            "protein_names": [
                {
                    "name": "Mitotic checkpoint serine/threonine-protein kinase BUB1 beta isoform X1",
                    "type": "synonym"
                },
                {
                    "name": "mitotic checkpoint serine/threonine-protein kinase BUB1 beta isoform X1",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "bub1ba",
                    "type": "recommended"
                },
                {
                    "name": "bub1ba",
                    "type": "synonym"
                }
            ],
            "record_id": "F1Q636-1",
            "evidence": [
                {
                    "id": "0080641",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080641"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "E7F5T9-1",
            "uniprot_ac": "E7F5T9",
            "uniprot_id": "E7F5T9_DANRE",
            "refseq_ac": "NP_001429377",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Danio rerio",
                    "taxid": 7955,
                    "common_name": "Zebrafish",
                    "glygen_name": "Zebrafish",
                    "reference_species": "Danio rerio [7955]"
                }
            ],
            "protein_names": [
                {
                    "name": "Mitotic checkpoint serine/threonine-protein kinase BUB1 beta",
                    "type": "synonym"
                },
                {
                    "name": "budding uninhibited by benzimidazoles 1 homolog beta b",
                    "type": "synonym"
                },
                {
                    "name": "mitotic checkpoint serine/threonine-protein kinase BUB1 beta",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "bub1bb",
                    "type": "recommended"
                },
                {
                    "name": "bub1bb",
                    "type": "synonym"
                },
                {
                    "name": "sb:cb730",
                    "type": "synonym"
                }
            ],
            "record_id": "E7F5T9-1",
            "evidence": [
                {
                    "id": "0080641",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080641"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q9Z1S0-1",
            "uniprot_ac": "Q9Z1S0",
            "uniprot_id": "BUB1B_MOUSE",
            "refseq_ac": "NP_033903",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
                {
                    "name": "Mitotic checkpoint serine/threonine-protein kinase BUB1 beta",
                    "type": "recommended"
                },
                {
                    "name": "2.7.11.1",
                    "type": "synonym"
                },
                {
                    "name": "BubR1",
                    "type": "synonym"
                },
                {
                    "name": "MAD3/BUB1-related protein kinase",
                    "type": "synonym"
                },
                {
                    "name": "Mitotic checkpoint kinase MAD3L",
                    "type": "synonym"
                },
                {
                    "name": "budding uninhibited by benzimidazoles 1 beta",
                    "type": "synonym"
                },
                {
                    "name": "budding uninhibited by benzimidazoles 1 homolog, beta",
                    "type": "synonym"
                },
                {
                    "name": "mitotic checkpoint kinase MAD3L",
                    "type": "synonym"
                },
                {
                    "name": "mitotic checkpoint serine/threonine-protein kinase BUB1 beta",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Bub1b",
                    "type": "recommended"
                },
                {
                    "name": "BUBR1",
                    "type": "synonym"
                },
                {
                    "name": "Bub1b",
                    "type": "synonym"
                },
                {
                    "name": "Mad3l",
                    "type": "synonym"
                }
            ],
            "record_id": "Q9Z1S0-1",
            "evidence": [
                {
                    "id": "0080641",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080641"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P47074-1",
            "uniprot_ac": "P47074",
            "uniprot_id": "MAD3_YEAST",
            "refseq_ac": "NP_012521",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Saccharomyces cerevisiae S288C",
                    "taxid": 559292,
                    "common_name": "Baker's yeast",
                    "glygen_name": "Yeast",
                    "reference_species": "Saccharomyces cerevisiae S288C [559292]"
                }
            ],
            "protein_names": [
                {
                    "name": "Spindle assembly checkpoint component MAD3",
                    "type": "recommended"
                },
                {
                    "name": "Mad3p",
                    "type": "synonym"
                },
                {
                    "name": "Mitotic MAD3 protein",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "MAD3",
                    "type": "recommended"
                },
                {
                    "name": "J1341",
                    "type": "synonym"
                },
                {
                    "name": "MAD3",
                    "type": "synonym"
                }
            ],
            "record_id": "P47074-1",
            "evidence": [
                {
                    "id": "0080641",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080641"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "F1LMI1-1",
            "uniprot_ac": "F1LMI1",
            "uniprot_id": "F1LMI1_RAT",
            "refseq_ac": "",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
            "protein_names": [
                {
                    "name": "Mitotic checkpoint serine/threonine-protein kinase BUB1 beta",
                    "type": "recommended"
                },
                {
                    "name": "2.7.11.1",
                    "type": "synonym"
                },
                {
                    "name": "MAD3/BUB1-related protein kinase",
                    "type": "synonym"
                },
                {
                    "name": "Mitotic checkpoint kinase MAD3L",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Bub1b",
                    "type": "recommended"
                }
            ],
            "record_id": "F1LMI1-1",
            "evidence": [
                {
                    "id": "0080641",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080641"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "O60566-1",
            "uniprot_ac": "O60566",
            "uniprot_id": "BUB1B_HUMAN",
            "refseq_ac": "",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Mitotic checkpoint serine/threonine-protein kinase BUB1 beta",
                    "type": "recommended"
                },
                {
                    "name": "2.7.11.1",
                    "type": "synonym"
                },
                {
                    "name": "MAD3/BUB1-related protein kinase",
                    "type": "synonym"
                },
                {
                    "name": "Mitotic checkpoint kinase MAD3L",
                    "type": "synonym"
                },
                {
                    "name": "Protein SSK1",
                    "type": "synonym"
                },
                {
                    "name": "hBUBR1",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "BUB1B",
                    "type": "recommended"
                },
                {
                    "name": "BUBR1",
                    "type": "synonym"
                },
                {
                    "name": "MAD3L",
                    "type": "synonym"
                },
                {
                    "name": "SSK1",
                    "type": "synonym"
                }
            ],
            "record_id": "O60566-1",
            "evidence": [
                {
                    "id": "0080641",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080641"
                }
            ]
        }
    ],
    "glycans": [],
    "biomarkers": [],
    "association_flag": "1000",
    "record_id": "doid.0080641"
}