{
    "biomarker_id": "AN6637-1",
    "biomarker_canonical_id": "AN6637",
    "condition": {
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            "resource": "Disease Ontology",
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            },
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            },
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            },
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                "description": ""
            },
            {
                "id": "DOID:2394",
                "resource": "Disease Ontology",
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                "name": "tumor of the Ovary",
                "description": ""
            },
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                "resource": "MONDO",
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                "name": "ovarian cancer",
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            },
            {
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                "description": ""
            },
            {
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                "url": "https://monarchinitiative.org/disease/MONDO:0008170",
                "name": "tumour of the ovary",
                "description": ""
            },
            {
                "id": "MONDO:0008170",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0008170",
                "name": "cancer of ovary",
                "description": ""
            },
            {
                "id": "MONDO:0008170",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0008170",
                "name": "cancer of the ovary",
                "description": ""
            },
            {
                "id": "MONDO:0008170",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0008170",
                "name": "malignant neoplasm of ovary",
                "description": ""
            },
            {
                "id": "MONDO:0008170",
                "resource": "MONDO",
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                "name": "malignant neoplasm of the ovary",
                "description": ""
            },
            {
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                "url": "https://monarchinitiative.org/disease/MONDO:0008170",
                "name": "malignant ovarian neoplasm",
                "description": ""
            },
            {
                "id": "MONDO:0008170",
                "resource": "MONDO",
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                "name": "malignant ovarian tumor",
                "description": ""
            },
            {
                "id": "MONDO:0008170",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0008170",
                "name": "malignant ovarian tumour",
                "description": ""
            },
            {
                "id": "MONDO:0008170",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0008170",
                "name": "malignant ovary neoplasm",
                "description": ""
            },
            {
                "id": "MONDO:0008170",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0008170",
                "name": "malignant tumor of ovary",
                "description": ""
            },
            {
                "id": "MONDO:0008170",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0008170",
                "name": "malignant tumor of the ovary",
                "description": ""
            },
            {
                "id": "MONDO:0008170",
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                "name": "malignant tumour of ovary",
                "description": ""
            },
            {
                "id": "MONDO:0008170",
                "resource": "MONDO",
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                "name": "malignant tumour of the ovary",
                "description": ""
            },
            {
                "id": "MONDO:0008170",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0008170",
                "name": "ovarian cancer",
                "description": ""
            },
            {
                "id": "MONDO:0008170",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0008170",
                "name": "ovarian cancer, somatic",
                "description": ""
            },
            {
                "id": "MONDO:0008170",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0008170",
                "name": "ovarian malignant tumor",
                "description": ""
            },
            {
                "id": "MONDO:0008170",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0008170",
                "name": "ovarian malignant tumour",
                "description": ""
            },
            {
                "id": "MONDO:0008170",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0008170",
                "name": "ovary cancer",
                "description": ""
            },
            {
                "id": "MONDO:0011931",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0011931",
                "name": "ovarian cancer, susceptibility to, 1",
                "description": ""
            },
            {
                "id": "MONDO:0011931",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0011931",
                "name": "OVCAS1",
                "description": ""
            },
            {
                "id": "MONDO:0011931",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0011931",
                "name": "ovarian cancer, susceptibility to",
                "description": ""
            },
            {
                "id": "MONDO:0011931",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0011931",
                "name": "ovarian cancer, susceptibility to, 1",
                "description": ""
            },
            {
                "id": "MIM:167000",
                "resource": "MIM",
                "url": "https://www.omim.org/entry/167000",
                "name": "Ovarian cancer",
                "description": "Ovarian cancer"
            }
        ],
        "id": "DOID:2394"
    },
    "biomarker_component": [
        {
            "biomarker": "increased PLG level",
            "assessed_biomarker_entity_id": "P00747-1",
            "assessed_entity_type": "protein",
            "assessed_biomarker_entity": {
                "recommended_name": "Plasminogen",
                "synonyms": []
            },
            "specimen": [
                {
                    "name": "ovary",
                    "namespace": "UBERON",
                    "id": "0000992",
                    "url": "http://purl.obolibrary.org/obo/UBERON_0000992",
                    "loinc_code": ""
                }
            ],
            "evidence_source": [
                {
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                    "database": "BiomarkerKB",
                    "url": "https://biomarkerkb.org/biomarker/AN6637-1"
                },
                {
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                    "database": "PubMed",
                    "url": "https://glygen.org/publication/PubMed/27935848",
                    "tags": [
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                        " biomarker",
                        " specimen"
                    ],
                    "evidence_list": [
                        {
                            "evidence": "PLG staining was positively associated with prolonged overall survival (OS) [hazard ratio (HR)=0.59, p=0.026] of the patients. In summary, these data indicate that elevated PLG expression represents a favorable prognostic biomarker in advanced (FIGO III/IV) high-grade serous ovarian cancer."
                        }
                    ]
                }
            ]
        }
    ],
    "best_biomarker_role": [
        {
            "role": "prognostic"
        }
    ],
    "evidence_source": [
        {
            "id": "AN6637-1",
            "database": "BiomarkerKB",
            "url": "https://biomarkerkb.org/biomarker/AN6637-1"
        },
        {
            "id": "27935848",
            "database": "PubMed",
            "url": "https://glygen.org/publication/PubMed/27935848",
            "tags": [
                "best_biomarker_role",
                " condition"
            ],
            "evidence_list": [
                {
                    "evidence": "PLG staining was positively associated with prolonged overall survival (OS) [hazard ratio (HR)=0.59, p=0.026] of the patients. In summary, these data indicate that elevated PLG expression represents a favorable prognostic biomarker in advanced (FIGO III/IV) high-grade serous ovarian cancer."
                }
            ]
        }
    ],
    "crossref": [
        {
            "id": "AN6637-1",
            "database": "BiomarkerKB",
            "url": "https://biomarkerkb.org/biomarker/AN6637-1",
            "categories": [
                "Biomarkers"
            ]
        }
    ],
    "citation": [
        {
            "title": "Plasmin(ogen) serves as a favorable biomarker for prediction of survival in advanced high-grade serous ovarian cancer.",
            "journal": "Biological chemistry",
            "authors": "Zhao S, Dorn J, Napieralski R, Walch A, Diersch S, Kotzsch M, Ahmed N, Hooper JD, Kiechle M, Schmitt M, Magdolen V",
            "date": "2017",
            "reference": [
                {
                    "type": "PubMed",
                    "id": "27935848",
                    "url": "https://glygen.org/publication/PubMed/27935848"
                }
            ],
            "evidence": [
                {
                    "id": "AN6635-2",
                    "database": "BiomarkerKB",
                    "url": "https://biomarkerkb.org/biomarker/AN6637-1"
                }
            ]
        }
    ],
    "section_stats": [
        {
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            "table_stats": [
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                    "count": 1
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            ],
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}