{
    "biomarker_id": "AN6278-7",
    "biomarker_canonical_id": "AN6278",
    "condition": {
        "recommended_name": {
            "id": "DOID:0040085",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0040085",
            "name": "bacterial sepsis",
            "description": "A bacterial infectious disease has_material_basis_in Bacteria."
        },
        "synonyms": [],
        "id": "DOID:0040085"
    },
    "biomarker_component": [
        {
            "biomarker": "increased IL6 level",
            "assessed_biomarker_entity_id": "P05231-1",
            "assessed_entity_type": "protein",
            "assessed_biomarker_entity": {
                "recommended_name": "Interleukin-6",
                "synonyms": [
                    {
                        "synonym": "Interferon beta-2"
                    },
                    {
                        "synonym": "IFN-beta-2"
                    },
                    {
                        "synonym": "CTL differentiation factor"
                    },
                    {
                        "synonym": "CDF"
                    },
                    {
                        "synonym": "B-cell stimulatory factor 2"
                    },
                    {
                        "synonym": "BSF-2"
                    },
                    {
                        "synonym": "Hybridoma growth factor"
                    }
                ]
            },
            "specimen": [
                {
                    "name": "blood",
                    "namespace": "UBERON",
                    "id": "0000178",
                    "url": "http://purl.obolibrary.org/obo/UBERON_0000178",
                    "loinc_code": "26881-3"
                }
            ],
            "evidence_source": [
                {
                    "id": "AN6278-7",
                    "database": "BiomarkerKB",
                    "url": "https://biomarkerkb.org/biomarker/AN6278-7"
                },
                {
                    "id": "32479790",
                    "database": "PubMed",
                    "url": "https://glygen.org/publication/PubMed/32479790",
                    "tags": [
                        "assessed_biomarker_entity",
                        " assessed_biomarker_entity_id",
                        " biomarker"
                    ],
                    "evidence_list": [
                        {
                            "evidence": "increased IL-6 expression is commonly used to support early sepsis diagnosis due to its rapid elevation after infection begins."
                        }
                    ]
                }
            ]
        }
    ],
    "best_biomarker_role": [
        {
            "role": "diagnostic"
        }
    ],
    "evidence_source": [
        {
            "id": "AN6278-7",
            "database": "BiomarkerKB",
            "url": "https://biomarkerkb.org/biomarker/AN6278-7"
        },
        {
            "id": "32479790",
            "database": "PubMed",
            "url": "https://glygen.org/publication/PubMed/32479790",
            "tags": [
                "best_biomarker_role",
                " condition"
            ],
            "evidence_list": [
                {
                    "evidence": "increased IL-6 expression is commonly used to support early sepsis diagnosis due to its rapid elevation after infection begins."
                }
            ]
        }
    ],
    "crossref": [
        {
            "id": "AN6278-7",
            "database": "BiomarkerKB",
            "url": "https://biomarkerkb.org/biomarker/AN6278-7",
            "categories": [
                "Biomarkers"
            ]
        }
    ],
    "citation": [
        {
            "title": "Clinical characteristics and risk factors associated with COVID-19 disease severity in patients with cancer in Wuhan, China: a multicentre, retrospective, cohort study.",
            "journal": "The Lancet. Oncology",
            "authors": "Tian J, Yuan X, Xiao J, Zhong Q, Yang C, Liu B, Cai Y, Lu Z, Wang J, Wang Y, Liu S, Cheng B, Wang J, Zhang M, Wang L, Niu S, Yao Z, Deng X, Zhou F, Wei W, Li Q, Chen X, Chen W, Yang Q, Wu S, Fan J, Shu B, Hu Z, Wang S, Yang XP, Liu W, Miao X, Wang Z",
            "date": "2020",
            "reference": [
                {
                    "type": "PubMed",
                    "id": "32479790",
                    "url": "https://glygen.org/publication/PubMed/32479790"
                }
            ],
            "evidence": [
                {
                    "id": "AN6278-2",
                    "database": "BiomarkerKB",
                    "url": "https://biomarkerkb.org/biomarker/AN6278-7"
                }
            ]
        }
    ],
    "section_stats": [
        {
            "table_id": "biomarker_component",
            "table_stats": [
                {
                    "field": "total",
                    "count": 1
                }
            ],
            "sort_fields": [
                "biomarker",
                "assessed_biomarker_entity_id",
                "assessed_entity_type",
                "assessed_biomarker_entity.recommended_name"
            ]
        },
        {
            "table_id": "citation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 1
                }
            ],
            "sort_fields": [
                "title",
                "journal",
                "authors",
                "date"
            ]
        }
    ]
}