[ { "cls_id": "homologset.agr.RGD:1308126", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q6NZ67-1", "uniprot_id": "MZT2B_HUMAN", "id": "Q6NZ67-1", "name": "Mitotic-spindle organizing protein 2B", "aln": "-MAAQGVGPGPGSAAPPGLEAAR-QKLALRRKKVLSTEEMELYELAQAAGGAIDPDVFKILVDLLKLNVAPLAVFQMLKSMCAGQRLASEPQ-DPAAVSLPTSSVPETRGRNKGSAALGGALALAERSSREGSSQRMPRQPSATR---LPKGGGPGKSPTRGST-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6P582-1", "uniprot_id": "MZT2A_HUMAN", "id": "Q6P582-1", "name": "Mitotic-spindle organizing protein 2A", "aln": "-MAAQGVGPGPGSAAPPGLEAAR-QKLALRRKKVLSTEEMELYELAQAAGGGIDPDVFKILVDLLKLNVAPLAVFQMLKSMCAGQRLASEPQ-DPAAVSLPTSSVPETRGRDKGSAALGGVLALAERSNHEGSSQRMPRQPSATR---LPKGGGPGKSPTQGST-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I5ZVW0-1", "uniprot_id": "A0A8I5ZVW0_RAT", "id": "A0A8I5ZVW0-1", "name": "", "aln": "-MAGAAGGGGAGLAVSTGLEAATLQKLALRRKKVLGAEEMELYELSQAAGAAIDPDVFKILVDLLNLNVAPLAVFQMLKSMCAGQRLASDPQ-DSVSMSLSTSTS-ETRGRNRGGPILGNVTIVAERGSRERPIQRMPRQPSATR---LPKVGGPGKSNSRSSP-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQ25-1", "uniprot_id": "MZT2_MOUSE", "id": "Q9CQ25-1", "name": "Mitotic-spindle organizing protein 2", "aln": "MAAAAAAAGGAALAVSTGLETATLQKLALRRKKVLGAEEMELYELAQAAGAAIDPDVFKILVDLLNLNVAPLAVFQMLKSMCAGQRLASDPQ-DSVPISLSTSTS-ETRGRNRGGPILGNVTISAERGSRERPIQRMPRQPSATR---LPKVGGSGKSNSRSSP-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6DC17-1", "uniprot_id": "MZT2_DANRE", "id": "Q6DC17-1", "name": "Mitotic-spindle organizing protein 2", "aln": "-MPSAPDSPSLSVNVSG-----NVQKYSIKKKKVLNAEETELFELTQAAGVVIDQEVFKIIVDLLKMNVAPLAVFQTLKTMCAGQKVSETSTGDASSTSHTTAVPTESRVRSKMSSGQG------EKSARESSSQRVPRQVSATRGQKSTKSSGSSSSSSQLTSN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. . . . .. ** ::::****.:** **:**:**** ** :****:****::********* **:*****:::. . *. . * .*: *:* *.: .. * *:. :* . **:*** **** .* .*...* :: :. ", "identical_positions": 63, "similar_positions": 48, "identity": "38.18%" }, { "cls_id": "homologset.agr.RGD:1308127", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XI53-1", "uniprot_id": "CACL1_RAT", "id": "Q5XI53-1", "name": "CDK2-associated and cullin domain-containing protein 1", "aln": "MEESMEEEEMLTYEAMMDDQNHNNWEAAVDSFRQPPPAPPLPPPPPPRPSSSIPDPGRELPGGQLLAVHAGSMDRKGLKEGLPMGSPPLSEPNGVIMMLKSCDAAAAVAKAAPAPTPSSTININTSTSKFLMNVITIEDYKSTYWPKLDGAIDQLLTQSPGDYIPISYEQIYSCVYKCVCQQHSEQMYSDLIKKITSHLERVSKELQASPPDLYIERFNIALGQYMGALQSIVPLFIYMNKFYIETKLNRDLKDDLIKLFTEHVAEKHIYSLM------------------------------QWVQMAPTLFSKFIPNILPPAVESELSEYAAQDQKLQRELIQNGFTRGDQSRKRAGDELAYNSPSACASSRGYR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R0X2-1", "uniprot_id": "CACL1_MOUSE", "id": "Q8R0X2-1", "name": "CDK2-associated and cullin domain-containing protein 1", "aln": "MEESMEEEEMLTYEAMMDDQNHNNWEAAADSFRQPPPAPPLPPPPPPRPSSSIPDPGRELPGGQLLAVHAGSMERKGPKEGLPMGPPPLPEPNGVIMMLKSCDAAAAVAKTAPAPTSSSTININTSTSKFLMNVITIEDYKSTYWPKLDGAIDQLLTQSPGDYIPISYEQIYSCVYKCVCQQHSEQMYSDLIKKITSHLERVSKELQASPPDLYIERFNIALGQYMGALQSIVPLFIYMNKFYIETKLNRDLKDDLIKLFTEHVAEKHIYSLMPLLLEAQSTPFQVTPSTMANIVKGLYTLRPEWVQMAPTLFSKFIPNILPPAVESELSEYAAQDQKLQRELIQNGFTRGDQSRKRAGDELAYNSPSACASSRGYR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86Y37-1", "uniprot_id": "CACL1_HUMAN", "id": "Q86Y37-1", "name": "CDK2-associated and cullin domain-containing protein 1", "aln": "MEESMEEEEGGSYEAMMDDQNHNNWEAAVDGFRQP-----LPPPPPP---SSIPAPAREPPGGQLLAVPAVSVDRKGPKEGLPMGPQPPPEANGVIMMLKSCDAAAAVAKAAPAPTASSTININTSTSKFLMNVITIEDYKSTYWPKLDGAIDQLLTQSPGDYIPISYEQIYSCVYKCVCQQHSEQMYSDLIKKITNHLERVSKELQASPPDLYIERFNIALGQYMGALQSIVPLFIYMNKFYIETKLNRDLKDDLIKLFTEHVAEKHIYSLMPLLLEAQSTPFQVTPSTMANIVKGLYTLRPEWVQMAPTLFSKFIPNILPPAVESELSEYAAQDQKFQRELIQNGFTRGDQSRKRAGDELAYNSSSACASSRGYR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RNS4-1", "uniprot_id": "A0A8M1RNS4_DANRE", "id": "A0A8M1RNS4-1", "name": "", "aln": "MEELQEIQELQQGGVCVDSDSSS----------------------------------------------------------------------------ESCESDASAAAAL----------LLNSGSKFLLNAMSAEEYRTVYWPKLERAVELLLTQSPMEHISISYEQIYSHVYKCVCQQHSELLYNDLMWKITSHLEQVSAELQASPPEHLIENFNLALSRYTAALHCIVPVFIYMNKFYIEAKLNRDLRDDLMKLFSDHVAEKHVATLLPLLKKAHSMPFQVNPSTMESVVKGLYTLRPDWVPLAPALFSRFIPQINPPALESQLPFYAAQDQKLQMELSQNGFSRGDQSRKRASEES---------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** * :* . :*.:. . :**:: *:.* : : .* ****:*.:: *:*::.*****: *:: ****** ::*.******** *********** :*.**: ***.***:** *******: **.**:**.:* .**:.***:**********:******:***:***::******: :*: :** :**:***:***:* ***:**:*. *******:* ** ****:*********.:* ", "identical_positions": 150, "similar_positions": 63, "identity": "39.79%" }, { "cls_id": "homologset.agr.RGD:1308128", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q86PD7-1", "uniprot_id": "QPCT2_DROME", "id": "Q86PD7-1", "name": "Glutaminyl-peptide cyclotransferase", "aln": "------------------------------MRLLLRNYSLMEAVKRLLPRPRKKIYNLGACFELVDIPKISYNPS-ELSEPRFLEYSNLSDKLHLREAIDK-ILIPRVVGTTNHSIVREYIVQSLR-DLD--WDVEVNSFHDHAPIKGKLHFHNIIATLNPNAERYLVLSCHYDSKYMPG---VEFLGATDSAVPCAMLLNLAQVLQEQLKPLK--------------KSKLSLMLLFFDGEEAFEEWGPKDS-IYGARHLAKKWHHEG----------KLDRIDMLVLLDLLG--APDPAFYSFFENTESWYMRIQSVETRLAKLQLLERYAS-------SGVAQRDPTRYFQSQAMRSSFIEDDHIPFLRRNVPILHLIPVPFPSVWHTPDDNASVIDYATTDNLALIIRLFALEYLLAGTEAK---------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VTH7-1", "uniprot_id": "Q9VTH7_DROME", "id": "Q9VTH7-1", "name": "glutaminyl-peptide cyclotransferase", "aln": "------------------------------MPCWRSFIALICLAIIVVVITICQSFHT-NFLTVGRNGTLRYEPT-ELNLGQMRMIAGLSDPENLRKNVQR-IAIKRAVSTPGHSEVRNYIVDYLK-KLN--WNVELDIFTQKVPIMSNVTFHNIVARQNPQTQRYLMFGCHYDSKYFKD---FDFMAATDSAVPCALMLNMATILKHQFH-----------------RSQVSLMLVFFDGEEAFGEWSQEDS-PYGSRHLAELWEKHG----------FLDKIDLFVLPDLIG--AKDVVFKKNILDTSGWFHRLVQLELKLFQAGIVR--------------SER-PLFKFEPGID----VDDDHLPFTRRNVPVIHLISNKYPAVWHQAEDVEMNVDYNTTEQVGLVLRMFVMEYLNSAPSISNTLK-----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "B5DFI7-1", "uniprot_id": "B5DFI7_RAT", "id": "B5DFI7-1", "name": "Glutaminyl-peptide cyclotransferase-like protein", "aln": "MSPASRGRSRQRLGDRGLMKPPSLSKRRLLPRVQLLPLLLLALALGLAFYIVWNSWHP-GVEEVSRSRDLRVPLIGSLSEAKLRLVVGQLDPQRLWGTFLRPLLIVRPPGSPGNLQVRKFLEATLQ-SLSAGWHVELDPFTASTPLG-PLDFGNVVATLDPGAARHLTLACHYDSKFFPPGL-PPFVGATDSAVPCALLLELVQALDVMLSRIKQ------------QAAPVTLQLLFLDGEEALKEWGPKDS-LYGSRHLAQIMESIPHSP----GPTRIQAIELFVLLDLLG--APSPIFFSHFPRTARWFQRLRSIEKRLHRLNLLQ--------------SHPQEVMYFQPGEPPGP-VEDDHIPFLRRGVPVLHLIAMPFPAVWHTPADTEANLHPPTVHNLSRILAVFLAEYLGL--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BH73-1", "uniprot_id": "QPCTL_MOUSE", "id": "Q8BH73-1", "name": "Glutaminyl-peptide cyclotransferase-like protein", "aln": "MSPGSRGRPRQRLEDRGLMKPPSLSKRRLLPRVQFLPLLLLALAMGLAFYIVWNSWHP-GVEEMSRSRDLRVPLIGSLSEAKLRLVVGQLDPQRLWGTFLRPLLIVRPPGSSGNLQVRKFLEATLQ-SLSAGWHVELDPFTASTPLG-PLDFGNVVATLDPGAARHLTLACHYDSKFFPPGL-PPFVGATDSAVPCALLLELVQALDAMLSRIKQ------------QAAPVTLQLLFLDGEEALKEWGPKDS-LYGSRHLAQIMESIPHSP----GPTRIQAIELFVLLDLLG--ASSPIFFSHFPRTARWFQRLRSIEKRLHRLNLLQ--------------SHPQEVMYFQPGEPPGP-VEDDHIPFLRRGVPVLHLIATPFPAVWHTPADTEANLHPPTVHNLSRILAVFLAEYLGL--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NXS2-1", "uniprot_id": "QPCTL_HUMAN", "id": "Q9NXS2-1", "name": "Glutaminyl-peptide cyclotransferase-like protein", "aln": "MRSGGRGRPRLRLGERGLMEPLLPPKRRLLPRVRLLP-LLLALAVGSAFYTIWSGWHR-RTEELPLGRELRVPLIGSLPEARLRRVVGQLDPQRLWSTYLRPLLVVRTPGSPGNLQVRKFLEATLR-SLTAGWHVELDPFTASTPLG-PVDFGNVVATLDPRAARHLTLACHYDSKLFPPGS-TPFVGATDSAVPCALLLELAQALDLELSRAKK------------QAAPVTLQLLFLDGEEALKEWGPKDS-LYGSRHLAQLMESIPHSP----GPTRIQAIELFMLLDLLG--APNPTFYSHFPRTVRWFHRLRSIEKRLHRLNLLQ--------------SHPQEVMYFQPGEPFGS-VEDDHIPFLRRGVPVLHLISTPFPAVWHTPADTEVNLHPPTVHNLCRILAVFLAEYLGL--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P43599-1", "uniprot_id": "YFI8_YEAST", "id": "P43599-1", "name": "Uncharacterized protein YFR018C", "aln": "-----------------------------MGMKYVLPLRLIGLAYLLVLFQVHR----------VTGWELSYEQYHAAHLN--EAINPDSGWNKSTKNLLLPFNRTRVPGSEGSREIQRFIIEHFNNTLAGEWAVETQAFEEN-----GYRFNNLVMTLQNNASEYLVLAAHYDTKIAPTG----MVGAIDSAASCAALLYTAQFLTHIACHERTKEYNDLESNTVVSNSTLGVKIVFFDGEEAIEEWGPEDS-IYGARRLAAQWLADG----------TMTRIRLLFLLDLLGSGEEEPLVPSYYAETHQEYQLLNRIEDDLLFRRGDEINGESALAAEVARQRKHLDPTDYRFLGLGHSVIGDDHTPFLAAGVPVLHAIPLPFPSTWHTVDDDFRHLDAAETRHWALLVCEFVVQSLRSRNQ-----------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VRQ9-1", "uniprot_id": "QPCT1_DROME", "id": "Q9VRQ9-1", "name": "Glutaminyl-peptide cyclotransferase", "aln": "------------------------------------------MAIGSVVFAAAG------------LLLLLLPPSHQQATAGNIGSQWRDDEVHFNRTLDS-ILVPRVVGSRGHQQVREYLVQSLN-GLG--FQTEVDEFKQRVPVFGELTFANVVGTINPQAQNFLALACHYDSKYFPND--PGFVGATDSAVPCAILLNTAKTLGAYLQKEFR------------NRSDVGLMLIFFDGEEAFKEWTDADS-VYGSKHLAAKLASKRSGSQAQLAPRNIDRIEVLVLLDLIG--ARNPKFSSFYENTDGLHSSLVQIEKSLRTAGQLE------------------GNNNMFLSRVSGGLVDDDHRPFLDENVPVLHLVATPFPDVWHTPRDNAANLHWPSIRNFNRVFRNFVYQYLKRHTSPVNLRFYRT--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8I936-1", "uniprot_id": "Q8I936_DROME", "id": "Q8I936-1", "name": "glutaminyl-peptide cyclotransferase", "aln": "--------------------------------------MLGRIALFLTIIY------------------VVFKAMFLRWVIEKPPFKFDDDEEHFNATLAK-LLKPRSVGSKGHAEVQDFIETELK---------RLDFITLKNDFQQGVNITNLVGFWNMRAKFYLMLTCHYDSKKPENVTTDEFLAAAEGAVSCAILLNVAKTLRQFLIDRWS------------EKKSVGLAFIFFDGHNSLSSDPYDENELLGATHFIDEEFIP------------LRDMAVAVTLSYIG--APNQTFLSFFEVTNDLHNLIADIEQDLRKSGELD-----------------DCHVLFQKKTHYDKDLLDDHIVFDEQDVPVIHVSPHEFPNVLYTPADNVENLHYPTIRNMIKIIRCFVHDFYEKWQYFMKWRQAFAINYDFYDD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . . : * .: . :: :: :. . : : : *:: : : .* : .***:* ::.* :.*..** :* . * : : ::*:**.::: . :. *: :: : : : . . :* . . . * . : :* * : *** * .**::* . :* . : * :. : :. * : ", "identical_positions": 31, "similar_positions": 76, "identity": "7.03%" }, { "cls_id": "homologset.agr.RGD:1308129", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9UFW8-1", "uniprot_id": "CGBP1_HUMAN", "id": "Q9UFW8-1", "name": "CGG triplet repeat-binding protein 1", "aln": "MERFVVTAPPARNRSKTALYVTPLDRVTEFGGELHEDGGKLFCTSCNVVLNHVRKSAISDHLKSKTHTKRKAEFEEQNVRKKQRPLTASLQCNSTAQTEKVSVIQDFVKMCLEANIPLEKADHPAVRAFLSRHVKNGGSIPKSDQLRRAYLPDGYENENQLLNSQDC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D4ADB4-1", "uniprot_id": "D4ADB4_RAT", "id": "D4ADB4-1", "name": "", "aln": "MERFVVTAPPARNRSKTALYVTPLDRVTEFGGELHEDGGKLFCTSCNVVLNHVRKSAISDHLKSKTHTKRKAEFEEQNVRKKQRPLTASLQCNSTAQTEKVSVIQDFVKMCLEANIPLEKADHPAVRAFLSRHVKNGGSIPKSDQLRRAYLPDGYENENQLLNSQDC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BHG9-1", "uniprot_id": "CGBP1_MOUSE", "id": "Q8BHG9-1", "name": "CGG triplet repeat-binding protein 1", "aln": "MERFVVTAPPARNRSKTALYVTPLDRVTEFGGELHEDGGKLFCTSCNVVLNHVRKSAISDHLKSKTHTKRKAEFEEQNVRKKQRPLTASLQCNSPAQTEKASVIQDFVKMCLEANIPLEKADHPAVRAFLSRHVKNGGSIPKSDQLRRAYLPDGYENENQLLSSQDC", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**********************************************************************************************.*****.*************************************************************.****", "identical_positions": 164, "similar_positions": 3, "identity": "98.2%" }, { "cls_id": "homologset.agr.RGD:1308131", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z1K5-1", "uniprot_id": "ARI1_MOUSE", "id": "Q9Z1K5-1", "name": "E3 ubiquitin-protein ligase ARIH1", "aln": "MDSDEGYNYEFDEDEECSEEDSGAEEEEDDDEDEPDDDNLDLGEVELVEPGLGVGGERDGLLCGETGGGGGSALGPGGGGGGGGGGGG--PGHEQEEDYRYEVLTAEQILQHMVECIREVNEVIQNPATITRILLSHFNWDKEKLMERYFDGNLEKLFAECHVINPSKKSRTR---QMNTRSSAQDMPCQICYLNYPNSYFTGLECGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHGCDILVDDNTVMRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKVQYPD----------AKPVRCKCGRQFCFNCGENWHDPVKCKWLKKWIKKCDDDSETSNWIAANTKECPKCHVTIEKDGGCNHMVCRNQNCKAEFCWVCLGPWEPHGSAWYNCNRYNEDDAKAARDAQERSRAALQRYLFYCNRYMNHMQSLRFEHKLYAQVKQKMEEMQQHN-MSWIEVQFLKKAVDVLCQCRATLMYTYVFAFYLKK-NNQSIIFENNQADLENATEVLSGYLERDISQDSLQDIKQKVQDKYRYCESRRRVLLQHVHEGYEKDLWEYIED---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZSJ6-1", "uniprot_id": "A0A8I5ZSJ6_RAT", "id": "A0A8I5ZSJ6-1", "name": "E3 ubiquitin-protein ligase ARIH1", "aln": "MDSDEGYNYEFDEDEECSEEDSGAEEEEDDDEDEPDDDNLDLGEVELVEPGLGVGGERDGLLCGETGGGGGSALGPGGGGGGGGGGGG--PGHEQEEDYRYEVLTAEQILQHMVECIREVNEVIQNPATITRILLSHFNWDKEKLMERYFDGNLEKLFAECHVINPSKKSRTR---QMNTRSSAQDMPCQICYLNYPNSYFTGLECGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHGCDILVDDNTVMRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKVQYPD----------AKPVRCKCGRQFCFNCGENWHDPVKCKWLKKWIKKCDDDSETSNWIAANTKECPKCHVTIEKDGGCNHMVCRNQNCKAEFCWVCLGPWEPHGSAWYNCNRYNEDDAKAARDAQERSRAALQRYLFYCNRYMNHMQSLRFEHKLYAQVKQKMEEMQQHN-MSWIEVQFLKKAVDVLCQCRATLMYTYVFAFYLKK-NNQSIIFENNQADLENATEVLSGYLERDISQDSLQDIKQKVQDKYRYCESRRRVLLQHVHEGYEKDLWEYIED---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y4X5-1", "uniprot_id": "ARI1_HUMAN", "id": "Q9Y4X5-1", "name": "E3 ubiquitin-protein ligase ARIH1", "aln": "MDSDEGYNYEFDEDEECSEEDSGAEEEEDEDDDEPDDDTLDLGEVELVEPGLGVGGERDGLLCGETGGGGGSALGPGGGGGGGGGGGGGGPGHEQEEDYRYEVLTAEQILQHMVECIREVNEVIQNPATITRILLSHFNWDKEKLMERYFDGNLEKLFAECHVINPSKKSRTR---QMNTRSSAQDMPCQICYLNYPNSYFTGLECGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHGCDILVDDNTVMRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKVQYPD----------AKPVRCKCGRQFCFNCGENWHDPVKCKWLKKWIKKCDDDSETSNWIAANTKECPKCHVTIEKDGGCNHMVCRNQNCKAEFCWVCLGPWEPHGSAWYNCNRYNEDDAKAARDAQERSRAALQRYLFYCNRYMNHMQSLRFEHKLYAQVKQKMEEMQQHN-MSWIEVQFLKKAVDVLCQCRATLMYTYVFAFYLKK-NNQSIIFENNQADLENATEVLSGYLERDISQDSLQDIKQKVQDKYRYCESRRRVLLQHVHEGYEKDLWEYIED---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PFJ9-1", "uniprot_id": "ARI1_DANRE", "id": "Q6PFJ9-1", "name": "E3 ubiquitin-protein ligase arih1", "aln": "MDSDEGYNYEFDDEEEE--------CSEDSGEEETADDTLELGEVELVDP-VVAGGERD--DCGETGGSG---LGPG----------------QDEEDYRFEVLTAEQILQHMVECIREVNEVIQNPATITRILLSHFNWDKEKLMERYFDGNLDKLFSECHVINPSKKSRTR---LMNTRSSAQDMPCQICYLNYPNSYFTGLECGHKFCMQCWGDYLTTKIIEEGMGQTISCPAHSCDILVDDNTVMRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKVQYPD----------AKPVRCKCGRQFCFNCGENWHDPVKCKWLRKWIKKCDDDSETSNWIAANTKECPKCHVTIEKDGGCNHMVCRNQNCKAEFCWVCLGPWEPHGSAWYNCNRYNEDDAKAARDAQERSRAALQRYLFYCNRYMNHMQSLRFEHKLYAQVKQKMEEMQQHN-MSWIEVQFLKKAVDVLCQCRSTLMFTYVFAFYLKK-NNQSIIFENNQADLENATEVLSGYLERDISQDSLQDIKQKVQDKYRYCESRRRVLLQHVHEGYDKDLWEYIED---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6NW85-1", "uniprot_id": "ARI1L_DANRE", "id": "Q6NW85-1", "name": "E3 ubiquitin-protein ligase arih1l", "aln": "MDSDEGYNYEFDDEEEEEEEE--EECSVDSGEEEAVDDSLELGEVELLDP-AVAGGEPD--DCADTGGGG---PGPG----------------QEDEDYRFEVLTTEQILQHMVECIRDVNEVIQNPATITRILLSHFNWDKEKLMERYFDGNLDKLFSECHVINPSKKPKTR---PMSTRSSSQDLPCQICYLNYPNSYFTGLECGHKFCMQCWGDYLTTKIIEEGMGQTISCPAHNCDILVDDNTVMRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKVQYPD----------AKPVRCKCGRQFCFNCGENWHDPVKCKWLRKWIKKCDDDSETSNWIAANTKECPKCHVTIEKDGGCNHMVCRNQNCKAEFCWVCLGPWEPHGSAWYNCNRYNEDDAKAARDAQERSRAALQRYLFYCNRYMNHMQSLRFEHKLYAQVKQKMEEMQQHN-MSWIEVQFLKKAVDVLCQCRSTLMFTYVFAFYLKK-NNQSIIFENNQADLENATEVLSGYLERDISQDSLQDIKQKVQDKYRYCESRRRVLLQHVHEGYEKDLWEYIED---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q94981-1", "uniprot_id": "ARI1_DROME", "id": "Q94981-1", "name": "E3 ubiquitin-protein ligase ariadne-1", "aln": "MDSDN--DNDFCDNVDS--------GNVSSGDD--GDDDFGM-EVDLPSS---ADRQMD------------------------------------QDDYQYKVLTTDEIVQHQREIIDEANLLLKLPTPTTRILLNHFKWDKEKLLEKYFDDNTDEFFKCAHVINPFNATEAI---KQKT-SRSQCEECEICFSQLPPDSMAGLECGHRFCMPCWHEYLSTKIVAEGLGQTISCAAHGCDILVDDVTVANLVTDARVRVKYQQLITNSFVECNQLLRWCPSVDCTYAVKVPYAE----------PRRVHCKCGHVFCFACGENWHDPVKCRWLKKWIKKCDDDSETSNWIAANTKECPRCSVTIEKDGGCNHMVCKNQNCKNEFCWVCLGSWEPHGSSWYNCNRYDEDEAKTARDAQEKLRSSLARYLHYYNRYMNHMQSMKFENKLYASVKQKMEEMQQHN-MSWIEVQFLKKAVDILCQCRQTLMYTYVFAYYLKK-NNQSMIFEDNQKDLESATEMLSEYLERDITSENLADIKQKVQDKYRYCEKRCSVLLKHVHEGYDKEWWEYTE----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VT94-1", "uniprot_id": "Q9VT94_DROME", "id": "Q9VT94-1", "name": "RBR-type E3 ubiquitin transferase", "aln": "MNSEMEFSDEDHGDSHRS-------LLTHMSCENDSDSEDTCTEILLPEN----SNSPE------------------------------------TEDFVYKVLSVDQIVQHQRNIIDEVNNVLNLPPQVTRIILNHFKWDKESLFENYFESNPKDFFQRAHVLNPFEKKIERE--SAASTSCAIPQLCGICFCSC--DELIGLGCGHNFCAACWKQYLANKTCSEGLANTIKCPAANCEILVDYISFLKLADDSEVVERYQQLITNTFVECNMLMRWCPAPNCSHAVKAVCAE----------PRAVLCKCGHEFCFACGENWHEPASCSSLKKWVKKCLEDSETSNWIAQNTKECPKCNVTIEKDGGCNHMVCKNPSCRYDFCWVCLGSWEPHGSSWYSCNRFDEEEAKQARLAQQKYRSSMARYLHYYNRYSNHMQSLKMENKLYSNIQAKMDDMQEE--MSWIEVQFLRDAVDVLCQCRTTLMYSYVFAFYLMN-NNQKIIFEDNQKDMEMATEKLSECLEREITVKNIYEVKQKVLDLSHYCQKRRHVLLCHVREGYENDWWEFKEETTT", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36113-1", "uniprot_id": "HEL1_YEAST", "id": "P36113-1", "name": "E3 ubiquitin-protein ligase HEL1", "aln": "MSSGTENDQFYSFDESDSSSIELYESHNTSEFTIHGLVFPKLISVTSQDSEFDINEDEDGVDTIYEGMLDAPLTKNNKRILCEG----------SVPNLSYECLTTKGIFERMLQRVDHLQPIFAIPSADILILLQHYDWNEERLLEVWTEKMDELLVELGLSTTANIKKDNDYNSHFREVEFKNDFTCIICCDKKDTETFA-LECGHEYCINCYRHYIKDKLHEG---NIITC--MDCSLALKNEDIDKVMGHPSSSKLMDSSIKSFVQKHNRNYKWCPFADCKSIVHLRDTSSLPEYTRLHYSPFVKCNSFHRFCFNCGFEVHSPADCKITTAWVKKARKESEILNWVLSHTKECPKCSVNIEKNGGCNHMVCS--SCKYEFCWICEGPWAPHGKNFFQCTMYKNNEDNKSKNPQDAN-KTLKKYTFYYRLFNEHEVSAKLDWNLGQTLGTKVHALQERIGISWIDGQFLSESLKVLNEGRTVLKWSFAVAYYSDASHNLTKIFVDNQMLLANAVESLSELLQIKTP-EVIMKRRPEFYNKAGYVENRTTALMECGRELLCKGICKAAE----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.* . : .: . . . : : :: *:.. *.:: : : . : :: *. *:*.*:.*::* *:* : : . :. .. . * ** . . : * ***.:* *: .*: * : *.* .*.: :. . .: .. : *.. . : * :*** :* *: .. . * *:. : *** ** : *.*..* *:**. .:** **: :*****:* *.***:******** .*: :***:* *.* ***. ::.*. :.::: : :: .*: :: :* .* . : :* * ::: :* : *:. :*:. :***: *** .::.:* : * .* :::..*:* :* . ** :** : *.* ** *: . . . : . : :. : * :.* .*: :* : : * ", "identical_positions": 113, "similar_positions": 161, "identity": "19.65%" }, { "cls_id": "homologset.agr.RGD:1308133", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9DAI6-1", "uniprot_id": "F135B_MOUSE", "id": "Q9DAI6-1", "name": "Protein FAM135B", "aln": "-MSEVQGTVEFSVELHKFYNVDLFQRGYYQIRVTLKVSSRIPHRLSASIVGQSESS---------------------------------------SLHSACVHESAVHSRVFQILYRNEEVSINDAMLFRVHLLLDGERVEDALSEVEFQLKVDLHFTDSEQQ----------------LRDVTGTPMISSRTLGLHFHPRRGLHHQVPVMFDYFHLSVISVAIHAALVALQQPLIS--------FTRPGRGSWLGKGGPDTGPEQPTISLENLVFGAGYCKPTSSEGSFYVPSENCIQHAHKWHRDLCLLLLHAYQGLRLYFLVIMRDIPELPTMELEALAVEET-----LSQLCSELQMLNNPEKIAEQISKDLAWLASHLMALWTQFLDTVTLHSQVTTYLTQEHHTLRVRRFSEAFFYMEHQKLAVLT---------FQENLIQTHSQLSLDIRNSEYLTSMPPLPAECLDIDGDWNTLPVIFEDRYVDCPVSGHNLSVYPNFDVPVTSPAIMNLKGKE-KNLINQNSSSRKDIPLSTTEAPQLGSDEDVTRR-------PEVQENVSTWNPIDVCSESQVYLTIG--EFQNRAG---IPEDECWTGPRPDAVKDSLTDTDICSRSPGPDEGQTPALTYIDVQSSNKY--CPRAELVQGINVQHEHRSSRESYGIVKTVPSK------VVAGTSQNNSTSLNQTAALELRTLGRGVNQDGKPVLLSLKLTPAEP-CDPPSTALREALDTKPSQPD-HAEEPEDLSALSGVIKRSASIISDSGIESEPSSVAWSEARSRALELPSDRDVLHQVVRRHAHHRNSLEGGHTESNTSLPSGIQASLSSISSLPFEEEERELALNKLTKSVSAPQISSPEESAEGADTI-KNTAGFSEDLDPS-----------SKENSPPRHTSLSYGGSRVQDVR-----------AGHSLADIALDSDRPQGPGYMDIPN---------------DKGNHPELQEPCCLDGMAETPLHVETKGLNLKIPCTIVLENSKSRSFHRAAGETAK-GKPEELS-MSKCVLSNNSISEVRAASHHRVPEISCSPAVEAVNLNSTG--VQNSSLSVNDTMTLNRRHNASLEAKHEAGTVCPTVTHTIASQVS-------------RNQELKTGTSISGSHLNSTEAFTLDSLKAVEVVNLSVSCTATCLPFSSVPKETPARAGLSSKQNPAPITHQPLGSFGVVSTYSSK-LEEEVSERMFSFYQAKEKFKKELKIEGFLYSDLSVLASDIPYFPPEEEEENLEDG-IHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEKNQTDTFADFDTMTDRLLDEIIQHIQLYNLSISRISFIGHSLGNIIIRSVLTRPRFRYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFLYQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDR-HTGPVYAEMINNLLGPLVEAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFFLVAGLNYFK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1LZ91-1", "uniprot_id": "F1LZ91_RAT", "id": "F1LZ91-1", "name": "", "aln": "-MSEVQGTVEFSVELHKFYNVDLFQRGYYQIRVTLKVSSRIPHRLSASIVGQTESS---------------------------------------SLHSACVHESVVHSRIFQILYRNEEVSINDAMLFRVHLLLDGERVEDALSEVEFQLKVDLHYTDSEQQ----------------LRDVTGTPMISSRTLGLHFHPRRGLHHQVPVMFDYFHLSVISVAIHAALVALQQPLIS--------FTRPGRGSWLGKGGPDTGPEQPTISLENLVFGAGYCKPTTSEGSFYVPSENCIQHAHKWHRDVCLLLLHAYRGLRLYFLVIMRDIPELPTMELEVLAVEET-----LSQLCSELQMLNNPEKIAEQISKDLAWLASHLMALWTQFLDTVTLHSHVTTYLTQEHHTLRVRRFSEAFFYMEHQKLAVLT---------FQENLIQTHSQLSMDIRNSEYLTSMPPLPAECLDIDGDWNTLPVIFEDRYVDCPVSGHNLSVYPNFEVPVTSPAIMKLKGKE-KSVINQKSSSRKEAPLSTTEAPELGSDEDVIQC-------PEMEENVSTQNPMDVCSESQVYLSIG--EFQNRAG---IPEDECWTGPRPDAVKDSLTDVDICRRSPGPEEGHTPALTYIDVESSNKN--YPRAEPVLGLNVQHEPRGSRDSYGIVKTMPSK------VLAGISQNNSISVNQTAALELRTLGRGVGQEGKPVLLSLKLTPAEP-CDPLSTGLREALDTKPSLPD-PGEEPEDLSVLSGVIKRSASIISDSGIESEPSSVAWSEARSRALEIPSDRDILHQVVRRHAHHRNSLEGGHTESNTSLPSAIQASLSSISSLPFEDEERELALTKLTKSVSAPQISSPEDTAEDSDTI-KNTAGFSEDLDLS-----------SKDNSSSRYSSPSYSGSRVQDVR-----------AGHSLADIAVASDRPQGPGYMDIHK---------------GNENHPDLQGPCCLDAMAENIPHVETKGLNLKIPCTTVLENPKTRSFHRTAVETAK-GKAKELS-LSKHMLSNNSISEVRAASHHRVPEISCAPAVGAGHLHSTG--VQNGSLSVNDTMTLNRRHNASPEAKHEAGTVCPTVTHTIASPVS-------------RNQELKAGTSISGSHLNSTEAFTLDSLKAVEVVNLSVSCTATCLPFSSVPKETPARAGLSSKQSPAPITHQPLGSFGVVSTYSSE-LEEEVSERMFSFYQAKEKFKKELKIEGFLYSDLSVLASDIPYFPPEEEEENLEDG-IHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEKNQMDTFADFDTMTDRLLDEIIQHIQLYNLSISRISFIGHSLGNIIIRSVLTRPRFRYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFLYQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDR-HTGPVYAEMINNLLGPLVEAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFFLVAGLNYFK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q49AJ0-1", "uniprot_id": "F135B_HUMAN", "id": "Q49AJ0-1", "name": "Protein FAM135B", "aln": "-MSEIQGTVEFSVELHKFYNVDLFQRGYYQIRVTLKVSSRIPHRLSASIAGQTESS---------------------------------------SLHSACVHDSTVHSRVFQILYRNEEVPINDAVVFRVHLLLGGERMEDALSEVDFQLKVDLHFTDSEQQ----------------LRDVAGAPMVSSRTLGLHFHPRNGLHHQVPVMFDYFHLSVISVTVHAALVALQQPLIS--------FTRPGRGSWLGKGGPDTGQEQSIISLENLVFGAGYCKPTSSEGSFYITSENCMQHAHKWHRDLCLLLLHAYRGLRLHFLVIMRDIPELPHTELEALAVEET-----LSQLCSELQMLNNPEKIAEQISKDLAWLTSHMMTLWTQFLDTVTLHSQVTTYLTQEHHTLRVRRFSEAFFYMEHQKLAVLT---------FQENLIQTHSQLSLDIRNSEYLTSMPPLPAECLDIDGDWNTLPVIFEDRYVDCPATGHNLSVYPNFDVPVTSPTIMNLKDKEDNCMVNSNLSFREDLVLSTIKPSQMDSDEEVIRC-------PEPGENVATQNHMDMCSESQVYISIG--EFQNKAG---VPEDECWTGQTSDAGTYPVADVDTSRRSPGPEDGQAPVLTYIDVKSSNKN--PSRAEPLVAFNAQHESRSSRDKYGLDRTGLSK------VVVGGSHQNAISSDKTTLHELSTLGKGIDQEGKMVLLSLKLTPSEP-CDPLSSTLREPLDIRSSLKDSHTEEQEELSVLSGVIKRSSSIISDSGIESEPSSVAWSEARSRALELPSDREVLHPFVRRHALHRNSLEGGHTESNTSLPSGIQASLTSISSLPFEEDEREVALTKLTKSVSAPHISSPEEAAEDADTK-QQDGGFAEPSDMH-----------SKSQGSPGSCSQLCGDS-GTDAG-----------ADHPLVEIVLDADNQQGPGYIDIPK---------------GKGKQFDAQGHCLPDGRTENTPGVETKGLNLKIPRVIALENPRTRSLHRALEETPK-GMPKDLN-VGQQALSNSGISEVEGLSQHQVPELSCTSAADAINRNSTGQQSQSGSPCIMDDTAFNRGVNAFPEAKHKAGTVCPTVTHSVHSQVL-------------KNQELKAGTSIMGSHLTSAETFTLDSLKAVEVVNLSVSCTATCLPFSSVPKETPARAGFSSKQTLFPITHQPLGSFGVVSTHSST-LDEEVSERMFSFYQAKEKFKKELKIEGFLYSDLTVLASDIPYFPPEEEEENLEDG-IHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEKNQMDTFADFDTMTDRLLDEIIQHIQLYNLSISRISFIGHSLGNIIIRSVLTRPRFRYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFLYQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDR-HTGPVYAEMINNLLGPLVEAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFFLVAGLNYFK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PSQ6-1", "uniprot_id": "A0A8M1PSQ6_DANRE", "id": "A0A8M1PSQ6-1", "name": "", "aln": "MMSEVQGTVEFSLELHKFHNVDLFQRGFYQVRAGLRVSPRVPHRITATTPGYTGEC---------------------------------------SFSNAGVHDGGVFSRIFQILYRNEEVTLEDHINFRLHLLLDGERVEEAVSEVDVQLKLDLHFTDNEQQ----------------LADISSVPVISSRTLGLHFHPQQGLHHHLPVMFDYFHLSVISVSIHASLVALHQPLIS--------FARSGKGTWLGKGSPESEAPPSAMSVENLMFGAGYCKPVPTEGSFYVPSENCLQRAYTWHRRICKLLLAAHRALRSYYTTLMKEIPQLQHIQTEDLPLEET-----LNQLTIELQLQSGHEKVAEQISKDLTQLCAQLSALWTQFLESTVPNPYIRSYLAQEHHTLRVRRFSEAYFFTEHPKESSLT---------FQEELINRHAQVSTEMRNSDYLLRMPPLPVECLDIDGDWSSLPIIFEDRYVDTPCLDYNVVHEQNQAVLNSQPCFEPTRVKGQTASPAEKTQDTSLPATSPEEPPSEDCTEMPTYMTLTDHQDDDVTEHIKPRPQAETLTDHVEEADIDGCEFITTSSNSRIHSVDEVTCQYENDGNTMSVDTDDVIDNQEKTSCQKEAANESDHTSSQQTNVFNSGQPLLLVPTDLGELPDLTSLGSFEFLPTYNHDDNLETPGDTGSPDNQEPQTVFDNRHIQAPAKDYGGKDTSPGILLKATLPGTDPLVTSPSRNVIHQIRRLS-ETPPRGVFLGGAKLMNRSSSVISDSGIESEPSSVAWTLEGRGVVAG--GRDILQSLARCRTAHQSSLEGLQTESHGSLPSATQASLTSISSLPYEEEE-DRQLNTLTKSASAPQISSPDDTEEDRETPNQETRTVCEANQVTGTRCEANPMRQNKESANEVKRNLQMEETTQQDTTNVLVANHIRDEAANEVKQTLQEVTREDGNTTTNQEKRNVCVANQLRKSEVAANEVKQNLQGVFREDGNETSNQEIDIEESSNQDITDLTFVNPEMLLYQQFLMDSGKDATLEELTENSKDFQGNILLKEYLMDESTEICRCEDEYCEHKRKLESNQYHKDADDISVCH-IHLNELEVASMENLPEP-TTNDKRTHGIAANEKERPADPIEPPTNERDQQILEGQSRINKVPSTGLAFVNK--KVVEVVNLSVSCAPTCLPFSSVLRDSPSVSGISTRQATSPITHQPLGSFGIISSNSFFGADQEINERMINFFKAKEALLRELVFRGTLYSDLPYLASEHPYFPPEEDDTEFEDG-IHLVVCVHGLDGNSADLRLVKTFVELGLPGSRLDFLMSERNQTDTFADFDTMTDRLLDEIIQHIQLYNLTIHRISFIGHSLGNVIIRSVLTRPRFRCYLCKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDHTDPRQTFLYTLSKKPGLQFFKNVVLVASPQDRYVPFHSARIEMCRTALKDR-TTGPVYTEMINNLLQPLLSAPNCRLIRQNVFHALPNTANTLIGRAAHIAVLDSELFLEKFLLVAGLNYFK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q12103-1", "uniprot_id": "YD109_YEAST", "id": "Q12103-1", "name": "Putative lipase YDL109C", "aln": "---MEAGRSADEVLYHNQSSVKLGELERYVITYELYQGDSIPADIT-------------------------------------------------------------LDSLWVKIKNTTKLSYKPAYLLGPFILYCDVRAKDYESSYKIICSADKPVFQSNLQ----------------AQQKFIAELS---------------LHHIKPRYVWIVDIVSQILFNKETKVTFEIVVG--------NSKA-------------------------------------------SLKRKIRCNDSLPDKACNILHTGLS------------VHRLTTADIWKVPRPID-----MSQKS-HLVILTHG--FQSNVSADMEYLMEEIYKAQMNNPNERLVIKGYMKNACETEKGIKFLGVGLANYIIDE----------------LYDDSVGKISFIGHSLGG-----------------------LTQTFAICYIKTKYPYFFKKVEPINFISLASPLLGIATSTPNYVKMSLSMG----------------------------------------------------------------------------------------------------------------------------------------------------------------IIGTTG----------------QELGLKDGNYGDKPLLYLLSEES----------------------------------------------------------------------LISVLARFKRRTLYANAVNDG-------------IVPLYSSSLLFLDYSQLLQKLGGQTTAPCDPLFQPEVSPI------------------------------------------------------------------------------------------------------------------------GELPNHSDVANDDDGINASSWNTFWKSKENNCDKKSKRLMNASVIKSMK-----------------------------------------------------------------------------------------------------------------------------------------SVLLSPCPDAKFFSDPDARVATIIHDKIYTEKNLPPPSPTLYEG-----TAAKE----------GETRKTRKEMEEIIAR-------------------RWHKG-MHWRKVVVLLKPDAHNNIIVRRRFSNAYGWPVVDHLVTAHFQRDDPIASPMQD---KQFAEEDINMATG------------GVEPN-------KFYSWLTKIEDPSVYHGG---IVSTASQLASS--------------------------------WISK-HSSVTD-----------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P53118-1", "uniprot_id": "ROG1_YEAST", "id": "P53118-1", "name": "Putative lipase ROG1", "aln": "----MSLTPTNEILFHYKSSVKVGELERYVITYHLYDGEEIPPDLN-------------------------------------------------------------LNSLWLKVRNMNPLSYRAAYLMGPFMLYCDVKTAQYHHSQKIVASVDYPKFEPNVQ----------------TQQDFVAELS---------------VHNIRQKYVWIADVMSQILFTTNTNVTYEVTIG--------TSKE-------------------------------------------SVEN----PHDLPSHLG-SYSPKLT------------VNRLTTLDLWNLPVQIT-----TPQKKKHLVVLTHG--LHSNVSTDLVYIMEQIYKAQKNYPHEQIVVKGYRGNVCQTEKGVKYLGTRLAEYIIQD----------------LYDESIRKISFVGHSLGG-----------------------LIQAFAIAYIYEVYPWFFKKVNPINFITLASPLLGIVTDNPAYIKVLLSFG----------------------------------------------------------------------------------------------------------------------------------------------------------------VIGKTG----------------QDLGLENDVEVGKPLLYLLSGLP----------------------------------------------------------------------LIEILRRFKRRTVYANAINDG-------------IVPLYTASLLFLDYNDILEQLQKLKENSKKSPLINDAS----------------------------------------------------------------------------------------------------------------------------TPVNQDFFNKTFISPLTKMLSILAPQKFPTENGSE-IPKVSFFESAS-----------------------------------------------------------------------------------------------------------------------------------------SILLPPLPERAYIMDPDSRDPVIIHDKIYNEDDIPQSEFDIEDG-----FFGKKNILLQAFFAGKKERAKYRNLEETIAR-------------------RWHEG-MAWRKVVVALKPDAHNNIIVRRKFANAYGWPVIDHLIDVHFNGDDDDDNDENDDINSTQVVEPIQSVTE------------GKKKYRKAENIPQEYGWLNKVETNGVFDEGPTGMISTVGEIVEA--------------------------------LAKRGFSAVIDRRNASEDPNDEVLRFEEMNSDLVQ-----------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "M9PGQ5-1", "uniprot_id": "M9PGQ5_DROME", "id": "M9PGQ5-1", "name": "DUF676 domain-containing protein", "aln": "-MGDLQATIEFVVELHKFFNVDLFQRGLYQVRCGLRVSPRLLVQVETSIPEASGPGKQNGHANGANATDHGSSDSERGELSPGEVPRLHESPPGGSCSSASVINGSGASRIFQILYRNEEVPLRDIIHFRSHLLVDSRHLKESIERAEFSLQLELWFGEQNGSSSLNGNGGGSGMGSFSGPASSALTLASTRNLQLNFHPGRGLHYHLPVLFDYFHLAAISVGIHASLVALHQPYIKKSVFSYMKFCAPRSSKPWSAGKLSCRGNTSPGPLEAVFFGPQIGGTTKCSG----GPAGRLLQSRAIHREICSLLLGAIEQLKATLNEFSTVLPPSINSQIGSPPLRENDTGERLQLLLDQAKQLEAEEDFAIRANSDIAQLCAESIFWWRRVLLASRSSTAVHTLLARKHHILRVRRFAEGFFVLEQPRHAAAAGCPDQTNGSPSPGHCQGYVAIAELARRSRYLQSLPPLPVHCTPIDGDASSLPLIFEDRYVTTNSTYARRRSGSDPQLEDAVSVVGVQKKKVDKTHSSSSLNGIKDCLACHFDYDYPQTNGSGPAHP---HAKCVITPRFALGGEVLQASLTIAPSKEAAPEAVAPPTLRHNLSRHSVTGLLEDLDLDSSLPARHSKSLDQLDGCEGLATNPVSTTNNHTLPRLQADDLMRNICEFRQRYGKFDYLHEIKLLNPPKQ----QQQAVPQQQQQCNNGYNSLPKSMVPPRNSYPPPPPSQHTTMPRSSSSQIPRAVEIARVRVSDIKEMLRQGQLRKESSSSESDMMQKLQMLSSNSVPFRLEGTSNNNTTSSDPNTSGFSESLPNLAPPPEFDSDSQLRRQRSNSTSSLSEESGWVSSRRSSLAISSPDTITSTGMTNRQRHTQLNLGMGMAMETRLNGEQLRLRLQKVLEQ-----------QQLQQQHPHKNRKRQAGTSSQSR--------------TPARQQTEVHKKISSVTVNIKRER-------------SRYQLDRLRHLPNGESTEVEEMEPPPRRNRHKTACEKSKSDFDITSLKDMQPLDAVCLPPPQQFQDQEQELALVLAPPPPDEFRDPPPEPAPAAPIAPVPPPAAALPPTGKTKIVACHLPPPLKERQPIGAIDNPVYHIYESLRPISTPAIFS-----------NKPVLKSHSLAELKRPQNLPNHSINHHCKTHAINANGNVLENGLDHEQDEIKENSNGQVRTNKQGHGSNTN--SKHKRKGQLASAVQEAPPSISLLEFEKYREEFRKQIKYQGSIYSDYVQLASELPYFYISDEYRAFSPNGMHLVICVHGLDGNSADLRLVRTYLELGLPGVNLEFLMSERNQGDTFSDFDTMTDRLVTEILYHIDSCALNPARISFVAHSLGTIIVRSALARPQMRPLLPRLHTFLSLSGPHLGTLYNTSGLVNMGMWFMQKWKKSGSLLQLCMRDTTDMRNSFLYRLSQRSTLHHFKNILLCGSSQDRYVPAHSARLELCKAAMRDSSSLGTIYREMVHNIIAPILARPELTLARFDVHHALPHTANTLIGRAAHIAVLDSELFIEKFMLIAGLKYFS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08448-1", "uniprot_id": "LPL1_YEAST", "id": "Q08448-1", "name": "Lipid droplet phospholipase 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTSDKHLFVLIHGLWGNYTHMESMRTILSTTLK-----------------------------------------------------------------------------------------------------------------------------------KEDVNDDMIYFLPKQNAMFKTFDGIEIIGYRTLIEVCEFIRDYK-------------------------------DGKITKLSVMGYSQGG-----------------------LVARFMIGKMLTEFKELFEDIEPQLFITMATPHLGVEFYNP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TGIAYKSALYSALRTLG---------------------------------------------------------------------------STILGKSGREMFIANS---------------------SNNILVKLSQGEYLEALSLFKWRIAFANVKNDRT---------------------------------------------------------------------------------------------------------------------------VAFYTAFITDCDPFIDFDNKLKYTFEEKIPGSGYKGILPKIVDLNALN----------------------------------------------------------------------------------------------------------------------------------------VNSHAPTKPTKTYKKWGRTILIILVATFLILPIALVMNGLG-----------------------TAYSYIVTCKYRKMLSN--------------G--------------ILHNEVRGKLGLTEQLKGYVTDAYGSIINSALDMDANYEASNSNLVNEEELPWKEFIQKYTTINDG----------VWKSKFKKLPFDENRKVILRNLNKLKWIRVPIYIKAVNAHGVIVAR---------------------------------RGMDENTAATGIACIEFTAQLLAYLMHKSN--------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . . . : . *: : . . : : :. * * : : : . . . : * . . . . . : . : : . :: . . . * . * .:. . : ", "identical_positions": 6, "similar_positions": 43, "identity": "0.38%" }, { "cls_id": "homologset.agr.RGD:1308134", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZM61-1", "uniprot_id": "A0A8I5ZM61_RAT", "id": "A0A8I5ZM61-1", "name": "BPTF-associated chromatin complex component 1", "aln": "MTSASTKVGEIFSAAGAAFTKLGELTMQLHPVSDSSPAGAKWTETEIEMLRAAVKRFGDDLNHISCVIKERTVAQIKTTVKRKVYEDSGIP---LPAESPKKGPKKMTSGVLSPP-NAPPPSSS-SVPEAGGPPIKKQKADVTLSALNDSDANSDLVDVEGLGETPPAKKLNFDQGRSPPPPTLAGVGKVLTWMVGDGPSRSPFLVQGPQKEDSAQGTGPVSNTTIEEVRVFLEKNPPCLLHLCPLYFLFQTA---------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DCT6-1", "uniprot_id": "BAP18_MOUSE", "id": "Q9DCT6-1", "name": "BPTF-associated chromatin complex component 1", "aln": "MTSASTKVGEIFSAAGAAFTKLGELTMQLHPVSDSSPAGAKWTETEIEMLRAAVKRFGDDLNHISCVIKERTVAQIKTTVKRKVYEDSGIP---LPAESPKKGPKKMTSGVLSPP-NAPPPSSS-SVPEAGVPPIKKQKADVTLSALNDSDANSDLVDVEGLGETPPAKKLNFDQA--------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IXM2-1", "uniprot_id": "BAP18_HUMAN", "id": "Q8IXM2-1", "name": "BPTF-associated chromatin complex component 1", "aln": "MTSASTKVGEIFSAAGAAFTKLGELTMQLHPVADSSPAGAKWTETEIEMLRAAVKRFGDDLNHISCVIKERTVAQIKATVKRKVYEDSGIP---LPAESPKKGPKKVASGVLSPPPAAPPPSSS-SVPEAGGPPIKKQKADVTLSALNDSDANSDVVDIEGLGETPPAKKLNFDQA--------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8IPA8-1", "uniprot_id": "Q8IPA8_DROME", "id": "Q8IPA8-1", "name": "Chromatin complexes subunit BAP18", "aln": "-MNSAIKVGEIFTAAGQAFSRLGDLTMQLHPNAESPSG--KWTDEEIDMLHSSIMRFSDDLTKISLSIKNRTVSQIRQALKKKAFEDAGIPAKQVPVQQVQHVLQTLPQQQPQQPLQQPPPQVFKSQPIVQHVQLVAQPKQIILHPQSNTTTTGTTVTVKQYQQMQKAAALAAAQAAASTANNTPTITEN--IIIQQPTSTTATVVQQPHMVSTCSSTQIVVPVVSAVSTVPTVLSPTVVIADDVVSTSNPPAAAATVGSPAGAPAGLKCGPDVSMTLNRINVQENEVDVEECLPAEVVKLDFVSEEVAG", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:: ******:*** **::**:******* ::*... ***: **:**:::: **.***.:** **:***:**: ::*:*.:**:*** :*.:. :: :.:.. . * ***. * * . : * :: * . .:: :.. * :: : * * *. ", "identical_positions": 62, "similar_positions": 58, "identity": "20.0%" }, { "cls_id": "homologset.agr.RGD:1308135", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5FVJ6-1", "uniprot_id": "BSCL2_RAT", "id": "Q5FVJ6-1", "name": "Seipin", "aln": "------------------------MVNDPPVPALLWAQEVGHVLAGRARRLMLQFGVLFCTILLLLWVSVFLYGSFYYSYMPTVSHLSPVHFYY-RTDCDSSTASLCSFPVANVSLTKSGRDRVLMYGQPYRVTLELELPESPVNQDLGMFLVTVSCYTRGGRIISTSSRSVMLHYRSQLLQMLDTLVFSSLLLFGFAEQKQLLEVELYSDYRENSYVPTTGAIIEVHSKRVQMYGAYLRIHAHFTGLRYLLYNFPMTCAFVGVASNFTFLSVIALFSYMQW-VWGAVWPRHRFSLQVNIRQRD---NSGHGAQRRISRHQPG----QASTQQSDVTEDGESPE-DPSGTEGQLSEEEKPEKQPLNGEGEQEPEAS----DGS--WEDAALLTEA------STSALAP--ETLGS-------LRQRQTCSSS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z2E9-1", "uniprot_id": "BSCL2_MOUSE", "id": "Q9Z2E9-1", "name": "Seipin", "aln": "------------------------MVNDPPVPALLWAQEVGHVLAGRARRLMLQFGVLFCTILLLLWVSVFLYGSFYYSYMPTVSHLSPVHFHY-RTDCDSSTASLCSFPVANVSLAKSGRDRVLMYGQPYRVTLELELPESPVNQDLGMFLVTVSCYTRGGRIISTSSRSVMLHYRSQLLQVLDTLLFSSLLLFGFAEQKQLLEVELYSDYRENSYVPTTGAIIEIHSKRIQMYGAYLRIHAHFTGLRYLLYNFPMTCAFVGVASNFTFLSVIVLFSYMQW-VWGAVWPRHRFSLQVNIRQRD---NSHHGAPRRISRHQPG----QESTQQSDVTEDGESPE-DPSGTEGQLSEEEKPEKRPLNGEEEQEPEAS----DGS--WEDAALLTEANPPTSASASALAP--ETLGS-------LRQRPTCSSS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96G97-2", "uniprot_id": "BSCL2_HUMAN", "id": "Q96G97-2", "name": "Seipin", "aln": "------------------------MVNDPPVPALLWAQEVGQVLAGRARRLLLQFGVLFCTILLLLWVSVFLYGSFYYSYMPTVSHLSPVHFYY-RTDCDSSTTSLCSFPVANVSLTKGGRDRVLMYGQPYRVTLELELPESPVNQDLGMFLVTISCYTRGGRIISTSSRSVMLHYRSDLLQMLDTLVFSSLLLFGFAEQKQLLEVELYADYRENSYVPTTGAIIEIHSKRIQLYGAYLRIHAHFTGLRYLLYNFPMTCAFIGVASNFTFLSVIVLFSYMQW-VWGGIWPRHRFSLQVNIRKRD---NSRKEVQRRISAHQPGPEGQEESTPQSDVTEDGESPE-DPSGTEGQLSEEEKPDQQPLSGEEELEPEAS----DGSGSWEDAALLTEANLPAPAPASASAPVLETLGSSEPAGGALRQRPTCSSS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A935-1", "uniprot_id": "A0AB13A935_DANRE", "id": "A0AB13A935-1", "name": "", "aln": "-------------------------MGAAMGPLLLWLQDVAAVTLLRARRTLLRAAILLCVLVLLLWVSIFLYGSFYYSYMPSVSFSTPVHYYY-RTDCEASDAVLCSFPMANVSLLKNGRDQVMMSGQAYRISLELEMPESPVNEQLGMFMVKMSCYSNDGTVVHSVARSTMLHYRSNLLQTLSTLLFSPLLLSGVSEQKQLVEVELFPDLKLDIYHPAVGAVIEIQSRRVQIYSAQLRIHAYFTGVRFLLYNFPVMSAIVGVASNFTFLSVIVLFSYLQF-IWGGLYPPEQVRVKVMIGDSTRLQQRREEARKRMHSSASTPVMTYGRDGSELLSDPLQHPK-QTVRNKGDLDTPSVIGTEDLNNQQEDETDDAPVFLDAPRGAESSLTEEDADDKQRMAGERNDTQEEETAQPQSSDTSLRQRPGPWMRL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58H682-1", "uniprot_id": "A0AC58H682_DANRE", "id": "A0AC58H682-1", "name": "", "aln": "--------MQSSTEELNSEDSGVQDVGPQIRGLVVEILETMSDLLVWMRWKAVEMVIIICVILLVFWVALFLYGSFYYSFMPTANFVAPVNFFHSRTDCPSPHHPMCSFPMANVSLLKNGKHQVMTYGQPYQITLKLEMPESPTNQQLGMFLVTITPYSKAGQIIGVSSRSAMLHYRSSLLQTLGTLVFSPMFLSGMSEQKQSVTVELFSEFKDDSYKPTVGAMLEIHAPNIQIYKANLYIFAHFTGIRYLLYQFPLISALMGVMTNFTFLSLIIVLSFLQFNLNGRQFRRKRIRRKRGSMSKA---RMQQEEMDEIDDLFDDP---SEPHDRGIIPENVDTMDSNSADMEESIPDVTGEDSDDSRELTKDEPICE----DGN---EETILRRRHLSQDSLQAPQVLT--ETTDKN------YYRVGVCSSS-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V3X4-1", "uniprot_id": "BSCL2_DROME", "id": "Q9V3X4-1", "name": "Seipin", "aln": "MNILLRLIVFALDPLGLGRRFLIRPAVNLGWNVYDRVRSKADEKVGTVRELVLRLGLIAFAVVLIIWLAVFMYAAFYYVYMPAISHTRPVHMQF---KTCLETSTPCTFPHAHVSLTK--KQQLLMVGQAYKVIVNIDMPESPQNLELGMFMVCAEMRDYDSMLRGHSCRSAMMRYRSPLIRMISTWVLSPLYVLGWKEEFQQVPVEIFSRYLEERQHPITDVYVEIQSQKIQFYTVTLHIVADFTGLRYIMFNWPVLSAIVAISTNLFFILVVFLLSWYHW---SDAKWLHSVQIKYARLTKS---LEPGVIHSKASSLRDDDDDLVAYSDKSDIADVGGDTLSDVDADDLVLVKKSRSGKRESPDALRKRPTKK--------------TTADH--------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * :. :: .::*::*:::*:*.:*** :**: .. **: . . *:** *:*** * :.::: **.*:: :::::**** * :****:* . : .**.*::*** *:: :.* ::*.: : * *: * : **::. : * ... :*::: .:*:* . * * * ***:*::::::*: .*::.: :*: *: :: ::*: :: . . . : . :.: : . : . .. ", "identical_positions": 63, "similar_positions": 109, "identity": "14.55%" }, { "cls_id": "homologset.agr.RGD:1308136", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LIM9-1", "uniprot_id": "A0ABK0LIM9_RAT", "id": "A0ABK0LIM9-1", "name": "Nephrocystin-1", "aln": "MLARRPRDPLQALRRRGQELKLQVDSLVTESQLTGALEPSKRRDIYQRCIQLKQAVDENKNALQKLNKADEAAPVGNYEQRKEEEHTLLEKLACQLQELAVGISRKDTLKVEAHSDKEEDDTTEDDEEETEETGGEEEESEGDEEGKQEQASP--EHAETVTYIALGDFAAQQAGDLTFKKGDILHIIEKRPDGWWLAKDAEGGEGLIPRTYLEPYNKEDKLESSEGSEEGDEEGVGEDGEDGEDGEDGEEDVEVVDETADGAQVKQRTDSHWSAVRKAISE--------------------------------------------------------INTVDVLATMGAIPAGFRPSTLSQLLDEGKAPYSIWLDLLARKPQGSPASVPQHWDTGGRFRASYFLQPELTTSQLAFRDLTWDAKTGTIMSRPSRVSLILTLWSCKMIPLPGTSIQVLSRHIRLCLFDGSKVLSNIHTVRAVWQPKKPKTWTFSPQVTGILPCLLDGDCFIRSNSSTPDLGILFELGISYIRNSTGERGELSCGWVFLKLFDASGVPIPAKTYELFLNGGTPYEKGVEVDPSVSRRAQGSVFRQMISVRRQPQLLVKLRSLNRRSRAMLSLLPETLVGSMCSAHLLIFYRQILGDVLLRDRTSLQSADLISHPVLATFPLLLEQPDVMDALRSSWAEKESTLKRSEKRDKELLKAEFLLVYHDCVLPLLHSTLLPPFRWAEEETEAARWKAIADFLKQSRENEGSLKALLSPDGVHKPFDLSEQTYDFLGEIRKNSG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QY53-1", "uniprot_id": "NPHP1_MOUSE", "id": "Q9QY53-1", "name": "Nephrocystin-1", "aln": "MLARRPRDPLQALRRRGQELKLQVDSLVTESQLTGALEPSKRREIYQRCIQLKQAVDENKNTLQKLNKADEAAPVGNYEQRKEEEHSLLEKLACQLQELAVSISRKDALKVEAHSDKEEDDTTEDDE---EETGGEEEESEGDGEGKQEQASPKQAETETVTYIALGDFAAQQTGDLTFKKGDVLHIIEKKPDGWWLAKDAEGVEGLIPRTYLEPYNKEDKLESSEGSEEGGEE-------------DGEEDVEVVDETADGAQVKQRTDSHWSAVRKAISEQ-------------------------------------------------------INTVDVLATMGAIPAGFRPSTLSQLLDEA----------------------------GNQFRASYFLQPELTTSQLAFRDLTWDAKAGTIMSRPSRVSLILTLWSCKMIPLPGTSIQVLSRHIRLCLFDGSKVLSNIHTVRAVWQPKKPKTWTFSPQVTGILPCLLDGDCFIRSNSSTPDLGILFELGISYIRNSTGERGELSCGWVFLKLFDASGVPIPAKTYELFLNGGTPYEKGVEVDPSVSRRAQGSVFRQMISVRRQPQLLVKLRSLNRRSRAMLSLLPETLVGSMCSAHLLIFYRQILGDVLLRDRTNLQSADLISHPVLATFPLLLEQPDVMDALRSSWSEKESTLKRAEKRDKELLKAEFLLVYHDCVLPLLHSTLLPPFRWAEEETEAARWKAIADFLKQSRENEGSLKALLSPDGVHKPFDLSEQTFDFLGEIRKNSG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15259-1", "uniprot_id": "NPHP1_HUMAN", "id": "O15259-1", "name": "Nephrocystin-1", "aln": "MLARRQRDPLQALRRRNQELKQQVDSLLSESQLKEALEPNKRQHIYQRCIQLKQAIDENKNALQKLSKADESAPVANYNQRKEEEHTLLDKLTQQLQGLAVTISRENITEVGAPTEEEEESESEDSE----DSGGEEEDAEEEEEEKEENESH--KWSTGEEYIAVGDFTAQQVGDLTFKKGEILLVIEKKPDGWWIAKDAKGNEGLVPRTYLEPYSEEE--EGQESSEEGSEE-----------------DVEAVDETADGAEVKQRTDPHWSAVQKAISEAGIFCLVNHVSFCYLIVLMRNRMETVEDTNGSETGFRAWNVQSRGRIFLVSKPVLQINTVDVLTTMGAIPAGFRPSTLSQLLEEG-----------------------------NQFRANYFLQPELMPSQLAFRDLMWDATEGTIRSRPSRISLILTLWSCKMIPLPGMSIQVLSRHVRLCLFDGNKVLSNIHTVRATWQPKKPKTWTFSPQVTRILPCLLDGDCFIRSNSASPDLGILFELGISYIRNSTGERGELSCGWVFLKLFDASGVPIPAKTYELFLNGGTPYEKGIEVDPSISRRAHGSVFYQIMTMRRQPQLLVKLRSLNRRSRNVLSLLPETLIGNMCSIHLLIFYRQILGDVLLKDRMSLQSTDLISHPMLATFPMLLEQPDVMDALRSSWAGKESTLKRSEKRDKEFLKSTFLLVYHDCVLPLLHSTRLPPFRWAEEETETARWKVITDFLKQNQENQGALQALLSPDGVHEPFDLSEQTYDFLGEMRKNAV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***** **********.**** *****::****. ****.**:.***********:*****:****.****:***.**:*******:**:**: *** *** ***:: :* * :::**:. :**.* ::*****::* : * *:*: * : ***:***:***.********::* :***:*****:****:* ***:********.:*: *..*.****.** ***.********:******.*****:***** *******:******************:*. .:***.******* .******** ***. *** *****:**************** ********:*******.***********.**************** ****************::***********************************************************:*****:****:**** *::::****************** :********:*.*** ***************:** .***:******:*****:***************: *******:******:**: **************** ************:****.*:*****.:**:*:*:*********:********:*****:***: ", "identical_positions": 538, "similar_positions": 100, "identity": "68.45%" }, { "cls_id": "homologset.agr.RGD:1308137", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "O88513-1", "uniprot_id": "GEMI_MOUSE", "id": "O88513-1", "name": "Geminin", "aln": "MNLSMKQKQEGAQENVKNSPVPRRTLKMIQPSADGSLVGRENELPKGLFKRKLWDDQLASQTSSCG---PEANENKDVGDLTQEAFDLISKENPSSQYWKEVAEQRRKALYEALKENEKLHKEIEQKDSEIARLRKENKDLAEVAEHVQYMAEVIERLSNEPLDNFESPDSQEFDSEEEAVEYSELEDSGAGTCAEETVSSSTDARPCT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75496-1", "uniprot_id": "GEMI_HUMAN", "id": "O75496-1", "name": "Geminin", "aln": "MNPSMKQKQEEIKENIKNSSVPRRTLKMIQPSASGSLVGRENELSAGLSKRKHRNDHLTSTTSSPGVIVPESSENKNLGGVTQESFDLMIKENPSSQYWKEVAEKRRKALYEALKENEKLHKEIEQKDNEIARLKKENKELAEVAEHVQYMAELIERLNGEPLDNFESLDNQEFDSEEETVEDSLVEDSEIGTCAEGTVSSSTDAKPCI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZWJ0-1", "uniprot_id": "D3ZWJ0_RAT", "id": "D3ZWJ0-1", "name": "", "aln": "MNLSMKQKQEGAQENVKSSPVPRRTLKMIQPSAAGSLVGRENELPKGLSKRKLWDDQLTSKISSCG---PEANENNSVGDLTQEACDLMTKENPSSQYWKEVAEQRRKALYEALTENEKLHKEIEQKDSEIARLRKENKDLAEVAEHVQYMAEVIEIY--------------LFYAHMFTVAVFRHTRRRFWIWIPLQMVVSHHVVAGI", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** ******* :**:*.*.************* **********. ** *** :*:*:* ** * **:.**:.:*.:***: **: **************:*********.*************.*****:****:*************:** * :. :* : * .. . ", "identical_positions": 120, "similar_positions": 30, "identity": "57.42%" }, { "cls_id": "homologset.agr.RGD:1308138", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4AAZ2-1", "uniprot_id": "D4AAZ2_RAT", "id": "D4AAZ2-1", "name": "Zona pellucida-like domain-containing protein 1", "aln": "MEQIWLLLLLAIRVFPGSAQFNSYNCDANLHSRFPAERDISVYCGVQAITMKINFCTVLFSGYSETDLALNGRHGDSHCRGFINNNTFPAVVIFIINLSTLEGCGNNLVVSTIPGVGASGNATSVQIGNISGYIDTPDPPTVISYLPGLLYKFSCSYPLEYLVNNTQLASSSAAISVRENNGTFVSTLNLLLYNDSTYREQLIIPSIGLPLKTKVFAAVQATNLDGRWNVLMDYCYTTPSGNPNDETRYDLFLSCDKDPQTTVIENGRSQRGRFSFEVFRFVKHKNQKMSTVFLHCLTKLCRADDCPLLMPICGNRKRRDAQSWTTWAPQSTSGNAVLSAGPIITRSDETPTNNSQLGSLSVPPFQLNAVTSSLISGMVILGVMCFSLLLCSLALLHRKGSTSLVLNGVRNPVFE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BGZ8-1", "uniprot_id": "ZPLD1_MOUSE", "id": "Q8BGZ8-1", "name": "Zona pellucida-like domain-containing protein 1", "aln": "MERVWLLFLLAIRVSPGSAQFNSYNCDANLHSRFPAERDISVYCGVQAITMKINFCTVLFSGYSETDLALNGRHGDSHCRGFINNNTFPAVVIFIINLSTLEGCGNNLVVSTIPGVGASGNATTVQIGNISGYIDTPDPPAVISYLPGLLYKFSCSYPLEYLVNNTQLASSSAAISVRENNGTFVSTLNLLLYNDSTYREQLIIPSIGLPLKTKVFAAVQATNLDGRWNVLMDYCYTTPSGNPNDDTRYDLFLSCDKDPQTTVIENGRSQRGRFSFEVFRFVKHKNQKMSTVFLHCLTKLCRADDCPLLMPICGNRKRRDAQSWTTWAPQSTSGNAVLSAGPIITRSDETPTNNSQLGSLSVPPFQLNAVTSSLISGMVILGVLCFSLLLCSLALLHRKGSTSLVLNGVRNPVFE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TCW7-1", "uniprot_id": "ZPLD1_HUMAN", "id": "Q8TCW7-1", "name": "Zona pellucida-like domain-containing protein 1", "aln": "MEQIWLLLLLTIRVLPGSAQFNGYNCDANLHSRFPAERDISVYCGVQAITMKINFCTVLFSGYSETDLALNGRHGDSHCRGFINNNTFPAVVIFIINLSTLEGCGNNLVVSTIPGVSAYGNATSVQVGNISGYIDTPDPPTIISYLPGLLYKFSCSYPLEYLVNNTQLASSSAAISVRENNGTFVSTLNLLLYNDSTYNQQLIIPSIGLPLKTKVFAAVQATNLDGRWNVLMDYCYTTPSGNPNDDIRYDLFLSCDKDPQTTVIENGRSQRGRFSFEVFRFVKHKNQKMSTVFLHCVTKLCRADDCPFLMPICSHRERRDAGRRTTWSPQSSSGSAVLSAGPIITRSDETPTNNSQLGSPSMPPFQLNAITSALISGMVILGVTSFSLLLCSLALLHRKGPTSLVLNGIRNPVFD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PLJ9-1", "uniprot_id": "A0A8M9PLJ9_DANRE", "id": "A0A8M9PLJ9-1", "name": "", "aln": "MEWMCVILVLFKGIHLAFSQFNGFNCDPNYHSRFPGERDISIYCGVQTITLKINLCPVLYSGYTDVDLALNSRHGEPQCRGFINNNTFPTAVLFSISLSSLEACGNTLQVSTTQGINAYGNISMVQMGNISGYIDTPDPPTVISYLPGLVYKFSCSYPLEYLLNNSQLASSSAAITVKDNNGTFLSTLSLVLYNDSTFNQLISIPVSGLSLKTRVFAAVKATNLDRRWNVLMDHCYATPSGNPKDEIRYDLFFGCYKDPQTTVFENGKSQMGRFAFEVFRFVKHKNQKMSTVFLHCITKLCRADDCAILMPICGKRRRRDSEAEHTVS-GSSSGDAVITAGPIITRSDESPTNNSQLVSSSSQP--LNAVTSALISGVVVLGVMSLGLFILSLRLLRKPSPS--NLTGLWNPSSR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** : ::::* : . :***.:***.* *****.*****:*****:**:***:*.**:***::.*****.***:.:***********:.*:* *.**:**.***.* *** *:.* ** : **:*************::*******:************:**:*********:*::*****:***.*:******:.: : ** **.***:*****:***** *******:**:******:*: *****:.* *******:***:** ***:*********************:*********.:*****.:*.***: * : *:**.**::**********:******* * * * ***:**:****:*:*** .:.*:: ** **:: ..: *.*: ** ", "identical_positions": 275, "similar_positions": 92, "identity": "66.27%" }, { "cls_id": "homologset.agr.RGD:1308139", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZXL5-1", "uniprot_id": "D3ZXL5_RAT", "id": "D3ZXL5-1", "name": "Nuclear cap-binding protein subunit 3", "aln": "MAAVRGLRVSVKAEAPAGPALGLPSPEVESGLERGEPEPMEVEEG--ELEIVPVRRSLKELLPDTSRRYENKAGSFITGIDVTSKEAIEKKEQRAKRFHFRAEVNLAQRNVALDRDMMKKAIPKVRLETIYICGVDEMSTQDIFSYFKEYPPAHIEWLDDTSCNVVWLDEMTATRALINMSSLPAQDKIRSREASEDK----SSEKDKKDK-QEDSSDDDETEEGEVED--------ENSSDVELDT-----------LSQVEEESLLRNDLRPANKLAKGNRLFMRFATKDDKKELGAARRSQYYMKYGNPNYGGMKGILSNSWKRRYHSRRIQRDVIK-KRALIGDDVGLTS-YKHRHSG-LVNVPEEPIEEEEEEEQEEE-----DQDMDADDRVVVEYHEELPALKQPRERSMSRRS-----SASSSDSDEMDYDLELRMISTPSPKKSMKMTMYADEVESQLKSIRNPMRSDSISTSNIKNRIG-------------------NKLPPEKFADVRHLLEEKRQ---HSCPRPAGGST-KPDIRQRLGKRPYSPEK------AFSSNQVVRREPSSDVHSRLGVPRQDVKGLYSDT-RERKSGGLWTRLGSTPKTKEK-NTKKVDHRASG------------------TEEDDSELQRAWGALIKEKEQ--SRQKKSRLDSLPSLQIEVSRESSSGSEAES", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BZR9-1", "uniprot_id": "NCBP3_MOUSE", "id": "Q8BZR9-1", "name": "Nuclear cap-binding protein subunit 3", "aln": "MAAVRGLRVSVKAEAPAGPALGLPSPEVESGLERGEPEPMEVEEG--ELEIVPVRRSLKELLPDTSRRYENKAGSFITGIDVTSKEAIEKKEQRAKRFHFRAEVNLAQRNVALDRDMMKKAIPKVRLETIYICGVDEMSTQDIFSYFKEYPPAHIEWLDDTSCNVVWLDEMTATRALINMSSLPAQDKMRSRDASEDK----SSEKNKKDK-QEDSSDDDETEEGEVED--------ENSSDVELDT-----------LSQVEEESLLRNDLRPANKLAKGNRLFMRFATKDDKKELGAARRSQYYMKYGNPNYGGMKGILSNSWKRRYHSRRIQRDVIK-KRALIGDDVGLTS-YKHRHSG-LVNVPEEPIEEEEEEEEEEE-----DQDMDADDRVVVEYHEELPGLKQPRERSLSRRS-----SASSSDSDEMDYDLELKMISTPSPKKSMKMTMYADEVESQLKSIRNPMRADSISTSNIKNRIG-------------------NKLPPEKFADVRHLLDEKRQ---HSCPRPAVSST-KPDIRQRLGKRPYSPEK------AFSSNQVVRREPSSDVHSRLGVPRQDVKGLYSDT-RERKSGGLWTRLGSTPKTKEK-NTKKVDHRASG------------------AEEDDSELQRAWGALIKEKEE--SRQKKSRLDSLPSLQIEVSRESSSGSEAES", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q53F19-1", "uniprot_id": "NCBP3_HUMAN", "id": "Q53F19-1", "name": "Nuclear cap-binding protein subunit 3", "aln": "MAAVRGLRVSVKAEAPAGPALGLPSPEAESGVDRGEPEPMEVEEG--ELEIVPVRRSLKELIPDTSRRYENKAGSFITGIDVTSKEAIEKKEQRAKRFHFRSEVNLAQRNVALDRDMMKKAIPKVRLETIYICGVDEMSTQDVFSYFKEYPPAHIEWLDDTSCNVVWLDEMTATRALINMSSLPAQDKIRSRDASEDK----SAEKRKKDK-QEDSSDDDEAEEGEVED--------ENSSDVELDT-----------LSQVEEESLLRNDLRPANKLAKGNRLFMRFATKDDKKELGAARRSQYYMKYGNPNYGGMKGILSNSWKRRYHSRRIQRDVIK-KRALIGDDVGLTS-YKHRHSG-LVNVPEEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRS-----SASSSDSDEMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVSSSNIKNRIG-------------------NKLPPEKFADVRHLLDEKRQ---HSRPRPPVSST-KSDIRQRLGKRPHSPEK------AFSSNPVVRREPSSDVHSRLGVPRQDSKGLYADT-REKKSGNLWTRLGSAPKTKEK-NTKKVDHRAPG------------------AEEDDSELQRAWGALIKEKEQ--SRQKKSRLDNLPSLQIEVSRESSSGSEAES", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q803E1-1", "uniprot_id": "NCBP3_DANRE", "id": "Q803E1-1", "name": "Nuclear cap-binding protein subunit 3", "aln": "MAAVRSLRVSVKSDSASDRSE--SDSESDSDRDAREAEPMEVEEGEVELESIPVRRSLKELLPDTSRRYENKAGTFITGIDVTSKEAIEKKEKRARRFHFRAEENLTQKDVVLERDLLKKMIPKVRLEALHMSGVDDMSTQDVFGYFKEYPPAHIEWIDDASCNVVWLDDITSTRALINLSRMPDKEEVTNTDSSKPSELPVQTQKARRSRGSDDDDDDDEEEEGEVDDDDDDDEEDEKARDIEDETEKKPQETRETSLSQAERDSLLQNEPRPTVKPFKGNKLFLRFATHDDKKELGAARRSRYYMKYGNPNYGGMKGILSNSWKRRYHTRRIQRDILKTKKPLIGDSMGHTPPYTHRHSADLVNLPEEPIEEEEEEEEDGE------EDMDADDR-VVEYKDRGEKERGPRLVEGGLRSRLGGPSPTSSDSDEMDYDLELKMISTPSPKKSMKMTMYADEVETNLRSLRNSIRTE--SSGSVKSRIGGGGGGGSGGAVEGRGEGGSSKSTSEKVTDVRQLLEEKRQGLSQQRSRPPVATSGKTDVRQRLGKRPHSPERRRSVSPVISRKTASRREPLSDVRSRLGVAKHDNRSLFSEPPKDKKTGGLWSRLGPSHKDSGSGDEDKPSSRASSSRGIRRRKDEDSDGVEDEDEEDDSHLQKMWGAMIKQKEQQSNKMKKSRLDNLPSLQIEISRDGSNGSDSDS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****.******:::.:. : ...* :*. : *.******** *** :*********:************:*****************:**:*****:* **:*::*.*:**::** *******::::.***:*****:*.************:**:********::*:******:* :* :::: . ::*: . .::* ::.: .:*..**** *****:* *:: *:* :* ***.*.:***:*: **: * ***:**:****:************:**************************:******::* *:.****.:* *. *.****. ***:************:: * :******* ****::. : ** . . ** *.:*************:*********************::*:.:**.:*:: *:..:*.*** .* ..**.:***:**:**** :. .**. .:: *.*:********:***: .:* : . **** ***:*****.::* :.*:::. :::*:*.**:***.: * . . : .* . **.. *****.**: ***:**:**: .: ******.*******:**:.*.**:::*", "identical_positions": 382, "similar_positions": 177, "identity": "54.18%" }, { "cls_id": "homologset.agr.RGD:1308141", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "B1H228-1", "uniprot_id": "ODAD1_RAT", "id": "B1H228-1", "name": "Outer dynein arm-docking complex subunit 1", "aln": "MRLGLSSRSARSEEGSEIFLEGPVDGELSRLHRQRKVMELERRAYSREVHQRIRKQVEEIRQLEMLRAKLQMQINVAQTQVKRLGDKKRLADMDHLLKCRAQVQIEIEALQEQNRALEKQIQDWETHILTQSKDISTPDVILDQKMKIQRRIRILEDQLDRVTCHFDIHLVRNAALREELELLRIERGRYLNMDRKLKKEIHLLQEMVGALSTSSTSAYTAREEAKTKMGMLQERAEKELAQSDTEAQILLRQISHLEQLHRFLKLKNHDRQPDPGVVQKEEQRAWETSEGLRKTSQEKLVLRYEDTLNKLAQLTGESDPDLLVEKYLELEERNFAEFNFINEQNSELYHLQEEIKEMQEALVSEHASQDKQSLERE-QQCKVLQQDVEKVCSESERLEARFQVLRVQLEKIKTDIQVLFDKAQCDNSVIKDLLGVKTYMRDRDIGLFLSTIEKRLVQLLTVQAFLEVQNNVPLADAALLALGQSIQEPPKKTTPLKPPDTMEDSSGVVIKDDYPMSKEELLSQVMKLVQLQDEEGSPK---------KRDSSPSLTLSSPRIS-LAAASVHARKASVVPESILSHKTGRGRGTGSISHVTFGDSASAPGPVTLASTSASGLP-------VSGRGSQGGRGAFKHTSSSSYLGSTGYLETSRGRESGTGGGHSQSMGSEMSRGFSSGSGQTSSAAPAS--RPSSATSKDSRGYN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UX62-1", "uniprot_id": "ODAD1_MOUSE", "id": "Q3UX62-1", "name": "Outer dynein arm-docking complex subunit 1", "aln": "------------------------------------MMELERRAYSKEVHQRLRKQVEEIRQLEMLRAKLQTQINVAQSQVKRLGDKKHLAEMECLLKSRAQVQVEIEALQEQNRALDKQIQDWETHVLTQSKEASAPDLIMYQKMKIQRRIRILEDQLDRVTCHFDIHLVRNAALREELELLRIERGRYLNMDRKLKKEIHLLREMVGALSTSSTSAYTAREEAKTKMGMLQERAEKELAQSDTEAQILLRQISHLEQLHRFLKLKNDERQPDPRVVQKAEQRDWEVSEGLRKTSQEKLVLRYEDTLGKLAQLTGESDPDLLVEKYLELEERNFAEFNFINEQNSEIHHLQEEIKEMQEALVSEHASQDKQRMQQE-QQCKMLQQDVDKMCSESEQLEGRFQVLRGQLEKIKTDIQVLFDKAKCDSSVIKDLLGVKTYMRDRDIGLFLSTIERRLVQLLTVQAFLQVQNLAPLADAALLALGQSLQEPSKKTTPLKPPDTMEDSSGAVIKEDYPMSKEELLSQVMKSLQLQDEEESAK---------KLDSSPSLTLSSPQIS-LVTVPKHSKKTSVVPESILSHKTNRGRGTGSVSHVTFGDSASAAGPVAMASASASGAP-------VSSRSSQGGRGGFKPTSSSSYLGSTGYLETSRGRESTAGGVHSQSMGSELSRGLSSSSGHASSPAPPS--RPSSSTSKDSRGYN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96M63-1", "uniprot_id": "ODAD1_HUMAN", "id": "Q96M63-1", "name": "Outer dynein arm-docking complex subunit 1", "aln": "-------------------------------------MEGERRAYSKEVHQRINKQLEEIRRLEEVRGDLQVQISAAQNQVKRLRDSQRLENMDRLLKGRAQVQAEIEELQEQTRALDKQIQEWETRIFTHSKNVRSPGFILDQKVKIRRRIRILENQLDRVTCHFDNQLVRNAALREELDLLRIDRNRYLNVDRKLKKEIHHLHHLVSTLILSSTSAYAVREEAKAKMGLLRERAEKEEAQSEMEAQVLQRQILHLEQLHHFLKLKNNDRQPDPDVLEKREKQAGEVAEGVWKTSQERLVLCYEDALNKLSQLMGESDPDLLVQKYLEIEERNFAEFNFINEQNLELEHVQEEIKEMQEALVSARASKDDQHLLQE-QQQKVLQQRMDKVHSEAERLEARFQDVRGQLEKLKADIQLLFTKAHCDSSMIDDLLGVKTSMGDRDMGLFLSLIEKRLVELLTVQAFLHAQSFTSLADAALLVLGQSLEDLPKKMAPLQPPDTLEDPPGFEASDDYPMSREELLSQVEKLVELQEQAEAQRQKDLAAAAAKLDGTLSVDLASTQRAGSSTVLVPTRHPHAIPGSILSHKTSRDR--GSLGHVTFGGLSSSTG--HLPSHITHGDPNTGHVTFGSTSASSGGHVTFRPVSASSYLGSTGYVGSSRGGENTEGGVESGGTASDSSGGLGSSRDHVSSTGPASSTGPGSSTSKDSRG--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VES4-1", "uniprot_id": "Q9VES4_DROME", "id": "Q9VES4-1", "name": "", "aln": "-------------MTDQSELDQLATAELQRLQRQHRGLQLDLRGLLEEKAKRLKKQNHMINVLQVEHQKLKEEIKTLEGGTHARKNTNREKHLGTLQEQQADLQRVLQNERTNLWELEGHIRKMEKEIDALRRNEVPDNCYKDTICKVQKSVVKLENRLDVVNKKCSDVLTENSKMRDAINHMLQDRANFNDMWQSMVTQFNEGKKFIMDLIDQSTLAFDQREELCNKLTVLKDRNENDKVMHIQEMREMQRRLEHDAKLQKFFDIKGQKR-LNPELEQRELDK-----KQSQKETYERQLLEYKEIIEKIKLLYGEEDADRLVAQFKRQEDENFALFNYVNELSHEVEVLNDSTQELQDEIERQKSEQTEKELKLKTEALDYLNAEKERIEQLAEETRERKRTLSIRLEQLLKGIEDIFRQLACDDAPILNVLSTKTFLTVHNVKLFIGVIERRVNLIISAINIEDNSNKILARKDRVPKFNIRESAKTKN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : *. .* :*:.** . *. *: : .*: :*.. : .: :.:: .: * : :*::* :: : : *: :*:. *..: : :: . . *::: : **::** *. : . *..*: :*: :: : :* .: :: :.: .::: :.:: * .** *: *** *: :*::* *:: . * : : *:: * :*::*:.:*...* :* : :: .: : * : *: :* *:: : *: * **.*.* ** :: . *:.*** **::** . *: :::. :*:*: : ::.: .: : : : . *: ::: . :*. . * : : :**:: .*: :* : **.: * ::*..** : ::: **:. **:*: :::. : . .. . : :. . .*: ", "identical_positions": 86, "similar_positions": 190, "identity": "12.04%" }, { "cls_id": "homologset.agr.RGD:1308142", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5RJQ0-1", "uniprot_id": "CHST1_RAT", "id": "Q5RJQ0-1", "name": "Carbohydrate sulfotransferase 1", "aln": "-----------------------------------------------------MQCSWKAVLLLALASIAIQYTAIRTFTAKSFHTCP-------GL--------------------------------------------------------------TETGLAERLCEEGPTFSYNL-SRKTHVLILATTRSGSSFVGQLFNQHMDVFYLFEPLYHVQNTLIPRFTQGKSPADRRVMLGASRDLLRSLYDCDLYFLENYIKPPPVNHTTDRVFRRGASRVLCSRPVCDPPGASDLILEEGDCVRKCGLLNLTLAAEACRERSHVAIKTVRVPEVNDLRALVEDPRLN-LKVIQLVRDPRGILASRSETFRDTYRLWRLWYGTGRKPYNLDVTQLTTVCEDFSSSVSTGLMRPSWLKGKYMLVRYEDLARNPMKKTEEIYEFLGIPLDSHVARWIQNNTRGD-PTLGKHKYGTVRNSAATAEKWRFRLSYDIVAFAQNACQHVLAQLGYKMATSEEELKNPAISLVEERDFRPFL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EQC0-1", "uniprot_id": "CHST1_MOUSE", "id": "Q9EQC0-1", "name": "Carbohydrate sulfotransferase 1", "aln": "-----------------------------------------------------MQCSWKAVLLLALASIAIQYTAIRTFTAKSFHTCP-------GL--------------------------------------------------------------TDTGLAERLCEEGPTFSYNL-SRKTHVLILATTRSGSSFVGQLFNQHMDVFYLFEPLYHVQNTLIPRFTQGKSPADRRVMLGASRDLLRSLYDCDLYFLENYIKPPPVNHTTNRVFRRGASRVLCSRPVCDPPGSSDLILEEGDCVRMCGLLNLTLAAEACRERSHVAIKTVRVPEVNDLRALVEDPRLN-LKVIQLVRDPRGILASRSETFRDTYRLWRLWYGTGRKPYNLDVTQLTTVCEDFSSSVSTGLMRPSWLKGKYMLVRYEDLARNPMKKTEEIYEFLGIPLDSHVAHWIQNNTRGD-PTLGKHKYSTVRNSAATAEKWRFRLSYDIVAFAQNACQQVLAQLGYKMANSEEELKNPAISLVEERDFRPFL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43916-1", "uniprot_id": "CHST1_HUMAN", "id": "O43916-1", "name": "Carbohydrate sulfotransferase 1", "aln": "-----------------------------------------------------MQCSWKAVLLLALASIAIQYTAIRTFTAKSFHTCP-------GL--------------------------------------------------------------AEAGLAERLCEESPTFAYNL-SRKTHILILATTRSGSSFVGQLFNQHLDVFYLFEPLYHVQNTLIPRFTQGKSPADRRVMLGASRDLLRSLYDCDLYFLENYIKPPPVNHTTDRIFRRGASRVLCSRPVCDPPGPADLVLEEGDCVRKCGLLNLTVAAEACRERSHVAIKTVRVPEVNDLRALVEDPRLN-LKVIQLVRDPRGILASRSETFRDTYRLWRLWYGTGRKPYNLDVTQLTTVCEDFSNSVSTGLMRPPWLKGKYMLVRYEDLARNPMKKTEEIYGFLGIPLDSHVARWIQNNTRGD-PTLGKHKYGTVRNSAATAEKWRFRLSYDIVAFAQNACQQVLAQLGYKIAASEEELKNPSVSLVEERDFRPFS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DBY9-1", "uniprot_id": "CHST1_DANRE", "id": "Q6DBY9-1", "name": "Carbohydrate sulfotransferase 1", "aln": "-----------------------------------------------------MQCSWKAVILLALVSIAIQYTAIRTFTAKPFHICPVPNPLNCGLG-------------------------------------------------------------QDVESFDRMCDEYPYFNYNS-SRKTHILILATTRSGSSFVGQLFNQHSDVFYLFEPLYHVQTTLIPHLSPSRYAVERRVMLGASRDLLRSLYNCDLYFLESYIKPQPANHTTDKLFRRGASKALCSMPVCDAFSPNDGNIEEGDCVRKCASLNLTLATESCRERRHVAIKTVRIPEVNDLKALIEDPRLN-LKVIQLVRDPRGILSSRIETFRDTYRLWRIWRATGRKPYNLDLTQLTTVCDDFLNSVSTGLSRPPWLRGRYMLVRYEDLARNPLQKTKEVYEFLGLSLEKGVVDWIHNNTRGNNDVSAKHKYGTLRDSAANAESWRLKLSHDIVDYTQTVCQHILDELGYKAVNSPEELKNMSISLIEDKTFIPFL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VMC4-1", "uniprot_id": "Q9VMC4_DROME", "id": "Q9VMC4-1", "name": "Sulfotransferase domain-containing protein", "aln": "--------------------------------------------------MVSLSRTSKLT--VACVGVYTTYVLFIFFLLPMLMPDPVTLQRSLVS------------------------------------------------------------------YSTSHLGDIRNLTLDAGGQPIRSMLVTFRGSGALTLLDNLAHQPGCYQHYAPLIAYESRSIAAK-EHHRALDE----------LAALYNCDYNKSAEMIQWGMRSPVFRRFYGA-------QAKICRSYSQ-------------EACWDPETMAAVCKLYPFINMAVYNL-RLNLLASLLERKDLN-LNIMLLVRDPRGTIYSR---------MNNKWCSDER-----DCEA-QELCGDMVSDYQMVETLTQAYPQRFSIIRYEDLFLQPDESIKQVFDFYGLPLERNRTRIQKMHPRSG---YFFQSSRWKELSSQSAFEWISEMMVDDIGAVQDVCGQAMDLWGYRSIQDFNHFSP--ESFQPIMDKAY--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VMC3-1", "uniprot_id": "Q9VMC3_DROME", "id": "Q9VMC3-1", "name": "Sulfotransferase domain-containing protein", "aln": "MSTGIGSSSSSTEEQQHLELSADLEACSLLGPQDPSNVDTGRTRAKQRLSLNGKRRRSRMSRRANLIGICGVSSLCILLLIATTQHRPLTTPFNQSAGRDQGASVDGGPSNSLARSAFYDRFQQQLQQQQQSSQTAVYNLTATIVDVLSAQRSRILAEMENFEYPRGGAERLTDMTPETNGTPVRSVVVTSWRSGSTFLGDILNSIPGNFYHYEPLLDFGIKQIRDPDDQELAVQN----------LKNLLNCDYADMIDYLNFGKTHTYLFEHNTR-------LWDVCREFP--------------RFCWRPAFLTRFCRLFPIQSMKTVRL-RLAQAEKLLEDQSLSSVRIVLLVRDPRGTMQSR---------RHRVWCGGNE-----DCEDPRLVCQDLRDDYKTAEVLLLKYPSRFRTVRYEDLSLSPSEMTQDILQFYGLPFDPAVEEFLDTHTKVN---IGGVSSTYRDSRS-APFHWMQDLKPEEIKQIQDVCTEAMDLWGYRRIENFNNFSTTQQTFDPMVMPPPFT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .: : * : : . : :::: **: : : : . : : ** * . . :. * * :** . :: . :* : *: : . .: .: *:* *. :.:: ******* : ** . * . . * :* *: .. . :: :***** .* : ::: * *:.:: . :.: . . : . * : : : * .* . : **: . :.:. :: ", "identical_positions": 41, "similar_positions": 86, "identity": "7.65%" }, { "cls_id": "homologset.agr.RGD:1308144", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CQE7-1", "uniprot_id": "ERGI3_MOUSE", "id": "Q9CQE7-1", "name": "Endoplasmic reticulum-Golgi intermediate compartment protein 3", "aln": "-------------------------------------------------------MEALGKLKQFDAYPKTLEDFRVKTCGGATVTIVSGLLMLLLFLSELQYYLTTEVHPELYVDKSRGDKLKINIDVLFPHMPCAYLSIDAMDVAGEQQLDVEHNLFKK-RLDKDGVPVSSEAERHELGKVEVTVFDPNSLDPNRCESCYGAE---------SEDIKCCNSCEDVREAYRRRGWAFKNPDTIEQCRREGFSQKMQEQKNEGCQVYGFLEVNKVAGNFHFAPGKSFQQSHVHVH-----DLQSFGLDNINMTHYIKHLSFGEDYP----------------GIVNPLDHTNVTAPQA--SMMFQYFVKVVPTVYMKV--DGEVLRTNQFSVTRHEKVANG---------LLGDQGLPGVFVLYELSPMMVKLTEKH-RSFTHFLTGVCAIIGGMFTVAGLIDSLIYHSARAIQKKIDLGKTT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZU83-1", "uniprot_id": "D3ZU83_RAT", "id": "D3ZU83-1", "name": "Endoplasmic reticulum-Golgi intermediate compartment protein", "aln": "MFAGLIAFEKASEGWSPTYALLRLRKTARGVTPTSGRKREAGGAGRLVSPFRPVPMEALGKLKQFDAYPKTLEDFRVKTCGGATVTIVSGLLMLLLFLSELQYYLTTEVHPELYVDKSRGDKLKINIDVLFPHMPCAYLSIDAMDVAGEQQLDVEHNLFKK-RLDKDGIPVSSEAERHELGKVEVTVFDPDSLDPNRCESCYGAE---------SEDIKCCNSCEDVREAYRRRGWAFKNPDTIEQCRREGFSQKMQEQKNEGCQVYGFLEVNKVAGNFHFAPGKSFQQSHVHVHAVEIHDLQSFGLDNINMTHYIKHLSFGEDYP----------------GIVNPLDHTNVTAPQA--SMMFQYFVKVVPTVYMKV--DGEVLRTNQFSVTRHEKVANG---------LLGDQGLPGVFVLYELSPMMVKLTEKH-RSFTHFLTGVCAIIGGMFTVAGLIDSLIYHSARAIQKKIDLGKTT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y282-1", "uniprot_id": "ERGI3_HUMAN", "id": "Q9Y282-1", "name": "Endoplasmic reticulum-Golgi intermediate compartment protein 3", "aln": "-------------------------------------------------------MEALGKLKQFDAYPKTLEDFRVKTCGGATVTIVSGLLMLLLFLSELQYYLTTEVHPELYVDKSRGDKLKINIDVLFPHMPCAYLSIDAMDVAGEQQLDVEHNLFKQ-RLDKDGIPVSSEAERHELGKVEVTVFDPDSLDPDRCESCYGAE---------AEDIKCCNTCEDVREAYRRRGWAFKNPDTIEQCRREGFSQKMQEQKNEGCQVYGFLEVNKVAGNFHFAPGKSFQQSHVHVH-----DLQSFGLDNINMTHYIQHLSFGEDYP----------------GIVNPLDHTNVTAPQA--SMMFQYFVKVVPTVYMKV--DGEVLRTNQFSVTRHEKVANG---------LLGDQGLPGVFVLYELSPMMVKLTEKH-RSFTHFLTGVCAIIGGMFTVAGLIDSLIYHSARAIQKKIDLGKTT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q803I2-1", "uniprot_id": "ERGI3_DANRE", "id": "Q803I2-1", "name": "Endoplasmic reticulum-Golgi intermediate compartment protein 3", "aln": "-------------------------------------------------------MDALNKLKQFDAYPKTLEDFRIKTCGGATVTIISGLIMLILFFSELQYYLTKEVHPELFVDTSRGDKLRINIDVIFPHMPCAYLSIDAMDVAGEQQLDVEHNLFKQ-RLDKDGQPVTTEAEKHDLGKEEEGVFDPSTLDPDRCESCYGAE---------TDDLKCCNTCDDVREAYRRRGWAFKTPDTIEQCKREGFSQKMQEQKNEGCQVYGFLEVNKVAGNFHFAPGKSFQQSHVHVH-----DLQSFGLDNINMTHFIKHLSFGKDYP----------------GIVNPLDDTNVAAPQA--SMMYQYFVKIVPTIYVKG--DGEVVKTNQFSVTRHEKIANG---------LIGDQGLPGVFVLYELSPMMVKFTEKQ-RSFTHFLTGVCAIIGGVFTVAGLIDSLIYHSARAIQKKIELGKAS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VUM3-1", "uniprot_id": "Q9VUM3_DROME", "id": "Q9VUM3-1", "name": "Endoplasmic reticulum-Golgi intermediate compartment protein 3", "aln": "-------------------------------------------------------MKFADVLRRLDAYPRTLDDFSVRTVGGAAVTIISTSIISLLIFLEVLNYMQPTLNEELFVDTTRDHKLRINLDVTLHNLACNYISLDAMDSSGDTHLRVDHDVFKH-RLDLNGEPLKETPIK------EIVAVSPPNKNVT-CGSCYGAE---------HNATHCCNTCEDVLDAYRLRKWTVA-VDKIEQCKG-KYKRSDEDAFKEGCRIQGHLEVNRMAGSFHFAPGKSFSIRQFHIH--------DFQFSNVKLSHTINHLSFGEKIEF---------------AKTHPLDGLRVDVAETK-SEMFNYYLKIVPTLYMRGNSDGEPIYTNQFSVTRYRKDLS-----------DRERGMPGIFFSYELSPLMVKYAERH-SSFGHFATNCCSIIGGVFTVAGILAVLLNNSWEAIQRKLEVGKLS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39727-1", "uniprot_id": "ERV46_YEAST", "id": "P39727-1", "name": "ER-derived vesicles protein ERV46", "aln": "-------------------------------------------------------MKRS-TLLSLDAFAKTEEDVRVRTRAGGLITLSCILTTLFLLVNEWGQFNSVVTRPQLVVDRDRHAKLELNMDVTFPSMPCDLVNLDIMDDSGEMQLDILDAGFTMSRLNSEGRPVGDATELHVGG--NGDGTAPVNNDPNYCGPCYGAKDQSQNENLAQEEKVCCQDCDAVRSAYLEAGWAFFDGKNIEQCEREGYVSKINEHLNEGCRIKGSAQINRIQGNLHFAPGKPYQNAYGHFHD----TSLYDKTSNLNFNHIINHLSFGKPIQSHSKLLGNDKRHGGAVVATSPLDGRQVFPDRNTHFHQFSYFAKIVPTRYEYL--DNVVIETAQFSATFHSRPLAGGRDKDHPNTLHVRGGIPGMFVFFEMSPLKVINKEQHGQTWSGFILNCITSIGGVLAVGTVMDKLFYKAQRSIWGKKSQ----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. * :**:.:* :*. ::* .*. :*: . :*:. * : . :* ** * **.:*:** : :.* :.:* ** :*: :* : . *. **: :* *: . : * . : * .****: : **: *: * .** *:. ..****. : . :: :***:: * ::*:: *.:******.:. *.* .*:::.* *:*****: . *** .* . :.*: *:*** * *. : * ***.* : : *:**:*. :*:**: * *:: :: * . : ***:::*. :: *: :: .:* * . ", "identical_positions": 103, "similar_positions": 113, "identity": "21.33%" }, { "cls_id": "homologset.agr.RGD:1308145", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K2W6-1", "uniprot_id": "PHF13_MOUSE", "id": "Q8K2W6-1", "name": "PHD finger protein 13", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDSDSCAAAFHPEEYSPTCKRRRTVEDFNKFCTFVLAYAGYIPYPKEELPLRSSPSPANSTAGTIDSDGWDTGFSDITPSVP----DRCFSHLQPSLLQRAKPSNYLLDRKTTDKLKKKKRRKRRDSDIPVKEGFRESLLKLEAADPYVETPSSPTMQDIPQASADPCSGWDSDTPSSGSCATVSPDQVTEIKTEGKRTIVRQGKQVVFRDEDSTGNDEDIMVDSDDDSWDLVTCFCMKPFAGRPMIECNECHTWIHLSCAKIRKSNVPEVFVCQKCRDSKFDIRRSNRSRMGSRKLFLD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86YI8-1", "uniprot_id": "PHF13_HUMAN", "id": "Q86YI8-1", "name": "PHD finger protein 13", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDSDSCAAAFHPEEYSPSCKRRRTVEDFNKFCTFVLAYAGYIPYPKEELPLRSSPSPANSTAGTIDSDGWDAGFSDIASSVPLPVSDRCFSHLQPTLLQRAKPSNFLLDRKKTDKLKKKKKRKRRDSDAPGKEGYRGGLLKLEAADPYVETPTSPTLQDIPQAPSDPCSGWDSDTPSSGSCATVSPDQVKEIKTEGKRTIVRQGKQVVFRDEDSTGNDEDIMVDSDDDSWDLVTCFCMKPFAGRPMIECNECHTWIHLSCAKIRKSNVPEVFVCQKCRDSKFDIRRSNRSRTGSRKLFLD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I5ZN36-1", "uniprot_id": "A0A8I5ZN36_RAT", "id": "A0A8I5ZN36-1", "name": "PHD finger protein 13", "aln": "CGPAPSERLRARCCRPLHRPGRAPPPRRPRPGGPYSGAGLPRPPLPLLPGSGPRAAPPGRGRGAGCAAGAGRSPRGPPCLSCGREAPGPAWPRDTPPPRSHRRPAPHGWAPHLPGPARAGRRRAPSAPGGRVGPWPPLRRRPALLSEALIPFPPAIFPGAKLKFFPSWSPVGSPCGLPSAGSARPTLLPVACGAGRGAGASGLLEQEYSPTCKRRRTVEDFNKFCTFVLAYAGYIPYPKEELPLRSSPSPANSTAGTIDSDGWDTGFSDITSSVP----DRCFSHLQPSLLQRAKPSDFLLDRKKTDKLKKKRRRKRRDSDVPGKEEYRGSLLKLEAADPYVEAPSSPTMQDIPQASADPCSGWDSDTPSSGSCATVSPDQVTEIKTEGKRTIVRQGKQVVFRDEDSTGNDEDIMVDSDDDSWDLVTCFCMKPFAGRPMIECNECHTWIHLSCAKIRKSNVPEVFVCQKCRDSKFDIRRSNRSRMGSRKLFLD", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .: *:.: :****:*****************************************************:*****:.*** *********:********::*****.*******::******* * ** :* .************:*:***:******.:************************.***************************************************************************************************** ********", "identical_positions": 261, "similar_positions": 25, "identity": "52.94%" }, { "cls_id": "homologset.agr.RGD:1308146", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AYI5-1", "uniprot_id": "SHOC2_RAT", "id": "Q6AYI5-1", "name": "Leucine-rich repeat protein SHOC-2", "aln": "--------------MSSS-------------------------LGKEKDSKEKDPKVPSA---------------KEREKEAKASGGFGKESKEKEPKTKGKDAKDGKKESSAAQPGVAFSVDNTIKRP--NPALGTRKKS----SNAEVTKELNKCREENSMRLDLSKRSIHILPPSVKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITAVEKDVRNLPRLSTLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNELLDLPDTIGNLSSLNRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDNPNLHSLPFELALCSKLSIMSIENCPLSHLPPQIVAGGPSFIIQFLKMQGPYRAMV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88520-1", "uniprot_id": "SHOC2_MOUSE", "id": "O88520-1", "name": "Leucine-rich repeat protein SHOC-2", "aln": "--------------MSSS-------------------------LGKEKDSKEKDPKVPSA---------------KEREKESKASGGFGKESKEKEPKAKGKDAKDGKKESSAAQPGVAFSVDNTIKRP--NPAPGTRKKS----SNAEVIKELNKCREENSMRLDLSKRSIHILPPSVKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLPKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNDLLDLPDTIGNLSSLNRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLSTLPRGIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDNPNLHSLPFELALCSKLSIMSIENCPLSHLPPQIVAGGPSFIIQFLKMQGPYRAMV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UQ13-1", "uniprot_id": "SHOC2_HUMAN", "id": "Q9UQ13-1", "name": "Leucine-rich repeat protein SHOC-2", "aln": "--------------MSSS-------------------------LGKEKDSKEKDPKVPSA---------------KEREKEAKASGGFGKESKEKEPKTKGKDAKDGKKDSSAAQPGVAFSVDNTIKRP--NPAPGTRKKS----SNAEVIKELNKCREENSMRLDLSKRSIHILPSSIKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDNPNLHSLPFELALCSKLSIMSIENCPLSHLPPQIVAGGPSFIIQFLKMQGPYRAMV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1L8Y7-1", "uniprot_id": "SHOC2_DANRE", "id": "Q1L8Y7-1", "name": "Leucine-rich repeat protein SHOC-2", "aln": "--------------MSST-------------------------LGKDKDSKEREP---------------------------KAEG---------KSKTKGKDAKDGKKDTSGASPAVAFTLDSTIKRP--NPPPSTRKKS----SNAEVIKELNKCREENSMRLDLSKRSIHLLPSSIKELTQLTELYLYSNKLQSLPPEVGCLSGLVTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPAVVYRVSSLTTLYLRFNRITTVEKDIKNLSKLTMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNDLLDLPETIGNLASINRLGLRYNRLSAIPRSLAKCRELEELNLENNNISVLPEGLLSSLVNLTSLTLARNCFQSYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDICGLVSLEMLTLSNNLLKKLPYGIGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTYLGLGENLLQHLPEEIGTLENLEDLYLNDNPNLHSLPFELALCSKLSIMSIENCPLSHLPPQIVAGGPSFIIQFLKMQGPYRAMV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VEK6-1", "uniprot_id": "SUR8_DROME", "id": "Q9VEK6-1", "name": "Leucine-rich repeat protein soc-2 homolog", "aln": "MNLCSSGATASTTSLSSTGQAERSGGVPGGGAEGGGGSGNSGGGGKTSNGSAEAPTLCFAGGSGTAGAIAGTEELSNANSPANGAGGATGSTGSGQQPTGSNGHSHLHNENNANMPPETRPKMVTVKHPESNKPKPTTKKSKPIQADQDVIKALQRCRDEGIKRLDLSKSSITVIPSTVKECVHLTELYLYSNKIGQLPPEIGCLVSLRNLALNENSLTSLPESLQNCSQLKVLDLRHNKLAEIPPVIYRLRSLTTLYLRFNRITAVADDLRQLVNLTMLSLRENKIRELGSAIGALVNLTTLDVSHNHLEHLPEDIGNCVNLSALDLQHNELLDIPDSIGNLKSLVRLGMRYNRLSSVPATLKNCKSMDEFNVEGNGITQLPDGMLASLSGLTTITLSRNQFASYPTGGPAQFTNVYSINLEHNRIDKIPYGIFSRAKGLTKLNMKENMLTALPLDIGTWVNMVELNLATNALQKLPDDIMNLQNLEILILSNNMLKKIPNTIGNLRKLRILDLEENRIEVLPHEIGLLHELQRLILQTNQITMLPRSIGHLGNLTHLSVSENNLQFLPEEIGSLESLENLYINQNPGLEKLPFELALCQNLKYLNIDKCPLSTIPPEIQAGGPSLVLQWLKMHSPYRQM-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :**: ** .:.. . * :. * : : .:. .. :::... * : . *:*:* * . * *** :: :* * *::**:*. ****** ** ::*.::** .:**********: .**.*:*** .* .***.********:**:* .:*::******** ***.*:**: *************:* .*:::* .*: **:*****::* : ** * ** ****:**:*****::****.::: ******:***:*::**** *: ***:******::* :* :* ::*:*:*.*.*: **:.:*:** *.::**:** * **.***:**:.:**:*:*****:***:******* *:*****:* **:****:***..********* * *:*:*: .* .**:* ****:***:* :******* ******::* **:**. *::**:*:* .**:: ***.**** ***:*.:.** * .******:**.**:**:*:**.*..********.:*. :.*::**** :**:* *****:::*:***:.*** * ", "identical_positions": 317, "similar_positions": 165, "identity": "49.38%" }, { "cls_id": "homologset.agr.RGD:1308147", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5M888-1", "uniprot_id": "CG025_RAT", "id": "Q5M888-1", "name": "UPF0415 protein C7orf25 homolog", "aln": "MSAYSMLSERIAMAKELIKRAESLSRSKK--GGIEGGAKLCSKLKSELKFLQKIESGKVAIKESHLQSTNLTHLKAIVESAENLEEVVSVLRVFGYTDSLGEKQTLVVDVVANGGHTWVKAIGRKAEALHNIWLGRGQYGDKSIIEQAEDFLQASRQQPVQYSNPHIVFAFYNSVSSPMADKLKDMGISVRGDIVAVNSLLNHPEEYL---------LSESE-------SDDEGQELLQVTRVDLDNVLARVAFPTEIKVDVCRRVNLDITTLITYVSAMSYGGCHFIFKEKVLTEQAEQERKERVLPQLEAFMKDKELFACESAVKDFQSILDTLGGPGERERAAVLIKRINVVPDQP--SERALKLVASSKINSRSLTIFGTGDTLKAITMTANSGFVRAANNQGVKFSVFIHQPRALTESKEALAVPLPKARTNDSAH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91WD4-1", "uniprot_id": "CG025_MOUSE", "id": "Q91WD4-1", "name": "UPF0415 protein C7orf25 homolog", "aln": "MSAYSMLSDRIVMAKELIKRAESLSRSRK--GGIEGGAKLCSKLKAELKFLQKIEAGKVAIKESHLQSTNLTHLKAIVESAENLEEVVSVLRVFGYTDTLGEKQTLVVDVVANGGHTWVKAIGRKAEALHNIWLGRGQYGDKSIIEQAEDFLQASRQQPVQYSNPHIVFAFYNSVSSPMADKLKDMGISVRGDIVAVNSLLNHPEEFQ---------LSESE-------SDDEGQELLQVTRVDRDNVLARVAFPTEIKVDVCKKVNLDITTLITYVSAMSYGGCHFVFKEKVLTEQAEQERKERVLPQLEAFMKDKELFACESAVKDFQSILDTLGGPGERERADVLIKRISVVPDQP--SERALRLVASSKINSRSLTIFGTGDTLKAITMTANSGFVRAANNQGVKFSVFIHQPRALTESKEAFAVPLPKDLTDDSAH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BPX7-1", "uniprot_id": "CG025_HUMAN", "id": "Q9BPX7-1", "name": "UPF0415 protein C7orf25", "aln": "MSAHSMLCERIAIAKELIKRAESLSRSRK--GGIEGGAKLCSKLKAELKFLQKVEAGKVAIKESHLQSTNLTHLRAIVESAENLEEVVSVLHVFGYTDTLGEKQTLVVDVVANGGHTWVKAIGRKAEALHNIWLGRGQYGDKSIIEQAEDFLQASHQQPVQYSNPHIIFAFYNSVSSPMAEKLKEMGISVRGDIVAVNALLDHPEELQ---------PSESE-------SDDEGPELLQVTRVDRENILASVAFPTEIKVDVCKRVNLDITTLITYVSALSYGGCHFIFKEKVLTEQAEQERKEQVLPQLEAFMKDKELFACESAVKDFQSILDTLGGPGERERATVLIKRINVVPDQP--SERALRLVASSKINSRSLTIFGTGDTLKAITMTANSGFVRAANNQGVKFSVFIHQPRALTESKEALATPLPKDYTTDSEH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q803H0-1", "uniprot_id": "CG025_DANRE", "id": "Q803H0-1", "name": "UPF0415 protein C7orf25 homolog", "aln": "MATYNTLQDRIRVAKELLERVDKICSRQG--REVEGRAKLCGKLRAELKFLQKVEAGKVVIKESHLQSTNLTHLKAIVESAESLEKVVSVLHVFAYESPDGQKQTLVVDVVANGGHTWVKSIGRKAEALHNIWQGRGQYGDKSVIRQAEDFLEASQQQPVQYSNPHIIFAFYNGVSSPMADKLKEMGISVRGDIVAVNTIEGGEEEDEEDQEGDHEDLVEEEEDGEDDNDDDSDDTDLMHTRVDRDTIVASLAFPTEVKVDVCNRVNLDITTLITYVSSLSHGNCHFTFKEVVLTEQAAQERQEKVLPRLEEFMKGKELFACQSAVEDFRVILDTLGGPGEKSRAEELLARLKVVPDQP--SERTQRLVMSSKVNRRSLMIFGTGDTLRAITMTANSGFVRAAANQGVRFSVFIHQPRALTEGKEWRATPI----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W0M6-1", "uniprot_id": "Q9W0M6_DROME", "id": "Q9W0M6-1", "name": "DUF1308 domain-containing protein", "aln": "MEEQEDREKLYEEAHKKVKLGEELKKALKDFEDLPGVSKVQRKIQQELKFLNKVIT-TRSVKEHHITSSNFVYYDFLIKTLRLQQGVVDINAVFRLES---RDSPLRVDIVANNGLKWVKVIARNSKSVEDAARGCVSIGARSVIDQAEDYLEASELSFCMFQRPKIVFYFSNKIEDSLHEELMEMGVQT--------ASLDSPDTDL------------------------------------------------DMYATTSNELNLDVTTLLAYVSALTNGSANWVYKEPLLTEQAERERASPLKPLLEKILEGKTLVCCQLAYDAFQSILDIVGGEGERKRAEELMKRVTVYPDVETIPEEFSHIRFTANVNERSLKIFSFGMARQIFTVTSNKAFVRSAKMQGINVPVFVHASVALTEGKQATGRPL----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . . *:: :: :.: : * :*: *:: *****:*: : . :** *: *:*:.: :::: . : **.: ** . ....* **:***.* .*** *.*:::::.: * . * :*:* ****:*:**. . :..*:*:* * * :...: ::* :**:.. : . : :: . ....:***:***::***::: *..:: :** :***** :** . : * ** :::.* *..*: * . *: *** :** **:.** *: *:.* ** .*. :: ::::* *** **. * : : :*:*:*..***:* **:...**:* . ****.*: . *: ", "identical_positions": 118, "similar_positions": 139, "identity": "26.76%" }, { "cls_id": "homologset.agr.RGD:1308149", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5EB97-1", "uniprot_id": "ZCH10_RAT", "id": "Q5EB97-1", "name": "Zinc finger CCHC domain-containing protein 10", "aln": "--MATPMHRLIARRQA----------------------EANKQHVRCQKCLEFGHWTYECKGKRKYLHRPSRTAELKKALKEKENR-LLQQSMGETNTERKTKKKRRPKSVTS--TSSSDSSASESSSESE-TSASSSSEDSDADGSLSSSSSSSAYSS-SSSSSSSSSSSSSDSDSSSSSSSSSSS-ESSSDDEPPKKRKKK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CX48-1", "uniprot_id": "ZCH10_MOUSE", "id": "Q9CX48-1", "name": "Zinc finger CCHC domain-containing protein 10", "aln": "--MATPMHRLIARRKA----------------------EANKQHVRCQKCLEFGHWTYECKGKRKYLHRPSRTAELKKALKEKENR-LLLQSIGETNIEKKIKKKKRSKSVTSSSTSSSDSSASESSSESE-TSASSSSEDSDSDESLSSSSSSSSSSACSSSSSSSSSSSSSDSDSSSSSSSSSSSSESSSDDEPQKKKKKKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TBK6-1", "uniprot_id": "ZCH10_HUMAN", "id": "Q8TBK6-1", "name": "Zinc finger CCHC domain-containing protein 10", "aln": "--MATPMHRLIARRQAFDTELQPVKTFWILIQPSIVISEANKQHVRCQKCLEFGHWTYECTGKRKYLHRPSRTAELKKALKEKENRLLLQQSIGETNVERKAKKK-RSKSVTSSSSSSSDSSASDSSSESEETSTSSSSEDSDTDESSSSSSSS-------ASSTTSSSSSDSDSDSSSSSSSSTST-DSSSDDEPPKKKKKK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VF05-1", "uniprot_id": "Q9VF05_DROME", "id": "Q9VF05-1", "name": "Zinc finger CCHC domain-containing protein 10", "aln": "MTLVGLAARKLAQKKR-----------------SAKQAADFPNGIRCQKCLQIGHWSYECKEKRKYVHRSSRTKQLSKRMSQKEADAPKNQVEEHSEVASSEGKKVRRKRKTSKSSSSSSSSSDSSDSSSE----SGSSSESDSSSSSSDSDDE-------EGSSSDSSGSGSDSDSSEDQKQGAPQKKKKRAGSSPESSDDQE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. * :*::: : :******::***:***. ****:**.*** :*.* :.:** * .:: . ** * * ** :***.**:..*.*.** *.**.:**:. * *.*... .*::.**.*.******......:. ... ... :. ..: ", "identical_positions": 61, "similar_positions": 64, "identity": "29.9%" }, { "cls_id": "homologset.agr.RGD:1308150", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z9R6-1", "uniprot_id": "D3Z9R6_RAT", "id": "D3Z9R6-1", "name": "", "aln": "MSVHMERLSPSGSWLVGCLFTIAIFQLPAQGSGSADKFYMAPLGSTANLSCPLRLWPNMAISQMRWHRPTHPPHPQAVHMFQDGQNSTEDLMPEYKGRTALVRDAHKGSYILQISNVRFEDRGLYQCQVWVGNSSQEDNVTLQVAVLGSDPYIHVKGYDAGWMELVCQSMGWFPEPRTEWRDPTGKALLSLSETHTLDEAGLFRTAVSSRIRGNALGNVSCTIRNKVLGQEKTTAMLITAPDPGSLSSPAVALSVVLPILGLLILLGIGLLCKQKKSREKLLYEQVMEVENLLEDHAKEKGRLHKALKKLRSELKLKRAAANAGWRRARLHFVAVTLDPDTAHPKLVLSEDRRCVRLGNRKRSVPDNPERFDFVVSVLGSEYFTTGCHYWEVYVGEKTKWILGVCSESVSRKGKVTASPANGHWLVRQSRGNEYEALTSPQTSFRLKESPKCVGIFLDYEAGVISFFNVTDKSHIFTFTHTFSSPLRPFFEPCLHDEGKNTAPLIICTELQKSEESIAPKQEGKGRANGDVSLKGPEMGSEKEQSPGAHLPEEGEGAKPWRVDDSKDSQTTSGE-EHGQESLLEGLHEQHSQKPWRKVTTQAGGPGDPMTFSSPETDEKPFTCAQCGKAFNNTSNLRTHQRIHTGEKPYKCSECGKSFSRSSNRIRHERIHLEEKHYQCARCQESFRRRSDLTTHQQDHLGQRPYRCDICGKSFSQSSTLAVHHRTHLEPAPYICCECGKSFSNSSSFGVHHRTHTGERPYECTECGRTFSDISNFGAHQRTHRGERPYRCTLCGKHFSRSSNLIRHQKTHLGEQDEKDSS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TDE8-1", "uniprot_id": "ZN691_MOUSE", "id": "Q3TDE8-1", "name": "Zinc finger protein 691", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGSEKEQRPEAHLPEEGEGAKPWRVDGSKDSQITPRE-DHGQESLLAGLHGTHPPKTRQKVTAQAGGPGDPMLFSSPETDEKLFICAQCGKTFNNTSNLRTHQRIHTGEKPYKCSECGKSFSRSSNRIRHERIHLEEKHYQCAKCQESFRRRSDLTTHQQDHLGQRPYRCDICGKSFTQSSTLAVHHRTHLEPAPYICCECGKSFSNSSSFGVHHRTHTGERPYECTECGRTFSDISNFGAHQRTHRGEKPYRCTLCGKHFSRSSNLIRHQKTHLGEQDEKDFS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5VV52-2", "uniprot_id": "ZN691_HUMAN", "id": "Q5VV52-2", "name": "Zinc finger protein 691", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSLCSPTHS------------------AEMSLF------------------------------------------LQGPEEMLP------------LSSEGSEMGSEKEQSPEPHLPEEGEGGKPWRVDDSEGSWIPPGEKEHGQESLSDELQETHPKKPWQKVTVRARELGDPIAHPRHEADEKPFICAQCGKTFNNTSNLRTHQRIHTGEKPYKCSECGKSFSRSSNRIRHERIHLEEKHYKCPKCQESFRRRSDLTTHQQDHLGKRPYRCDICGKSFSQSATLAVHHRTHLEPAPYICCECGKSFSNSSSFGVHHRTHTGERPYECTECGRTFSDISNFGAHQRTHRGEKPYRCTVCGKHFSRSSNLIRHQKTHLGEQAGKDSS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ******* * .********.******.*:.* .. * :****** *: *. *. :***.:* ***: .. *:*** * ******:************************************************:*.:********************:************:**:********************************************************************:*****:********************** ** *", "identical_positions": 233, "similar_positions": 27, "identity": "28.38%" }, { "cls_id": "homologset.agr.RGD:1308152", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5FVM5-1", "uniprot_id": "CR3L3_RAT", "id": "Q5FVM5-1", "name": "Cyclic AMP-responsive element-binding protein 3-like protein 3", "aln": "MDGDISTGKMASPACAMAPLDSMEVLDLLFDGQDGILRNVDLAES---WILTREEQKVLPNSDSDEFLNSILGPGDSDPSSPIWSPADSDSGISEDLPSDSQDTPPGSGPGSANVAARCHPSKQGEGPCPSYLPSTACPEP---PRTQVHESSVAIDLDMWSTD----TLYPEEQAGSPSRFNLTVKELLLSGGGGDLQQHPLAASQLLGPGSGHCQELVLTEDEKKLLAKEGVTLPTQLPLTKYEERVLKKIRRKIRNKQSAQESRKKKKEYIDGLENRMSACTAQNQELQRKVLHLEKQNLSLLEQLKHLQALVVQSTSKPAHAGTCIAVLLLSFVLIILPSISPFTANKVDSPGDFIPVRVFSRTLHNHAASRVAPDVTPGPEVPG-------PHKG-SSGGLSADWGNFLEIPMLDDPTEELDNTTLVLANSTEDLGRATLLDWVASEPLL--GQMGLEIPGEEIWLSWVPRWLRVRVVQDALGVL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91XE9-1", "uniprot_id": "CR3L3_MOUSE", "id": "Q91XE9-1", "name": "Cyclic AMP-responsive element-binding protein 3-like protein 3", "aln": "MDGDIAAGKMASPVCAMAPLDSMEVLDLLFDRQDGILRNVELAEG---WILAREEQKVLLNSDSDEFLNCILGPGDSDPSSPLWSPADSDSGISEDLPSDPQDTPPRSGTEPANTVARCHTREQGKGPCPSYLPSTPCPEP---PRTQVQESSVAIDLDMWSTD----TLYPEEPAGSPSRFNLTVKELLLSGGSGDLQQHSLAASQLLGPGSGHCQELVLTEDEKKLLAKEGVTLPTQLPLTKYEERVLKKIRRKIRNKQSAQESRKKKKEYIDGLENRMSACTAQNQELQRKVLHLEKQNLSLLEQLKHLQALVVQSTSKPAHAGTCIAVLLLSFALIILPSISPFNSNKVDSPGDFVPVRVFSRTLHNHAASRVAPDVTPGSEVPGPWPDVGTPHKGPSSGGLSADWGNFLEIPMLDNLTEELDNSTLVLANSTEDLGRATLLDWVASEPLLSPGRVGLEIPG-EMWLSWVPRWLRVRLVQDALGVL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q68CJ9-1", "uniprot_id": "CR3L3_HUMAN", "id": "Q68CJ9-1", "name": "Cyclic AMP-responsive element-binding protein 3-like protein 3", "aln": "MNTDLAAGKMASAACSMDPIDSFELLDLLFDRQDGILRHVELGEG---WGHVKDQQ-VLPNPDSDDFLSSILGSGDSLPSSPLWSPEGSDSGISEDLPSDPQDTPPRSGP--ATSPAGCHPAQPGKGPCLSYHPGNSCSTTTPGPVIQVPEASVTIDLEMWSPGGRICAEKPADPVDLSPRCNLTVKDLLLSGSSGDLQQHHLGASYLLRPGAGHCQELVLTEDEKKLLAKEGITLPTQLPLTKYEERVLKKIRRKIRNKQSAQESRKKKKEYIDGLETRMSACTAQNQELQRKVLHLEKQNLSLLEQLKKLQAIVVQSTSKSAQTGTCVAVLLLSFALIILPSISPFGPNKTESPGDFAPVRVFSRTLHNDAASRVAADAVPGSEAPGPRPEADTTREE-SPGSPGADWG-FQDTANLTNSTEELDNATLVLRNATEGLGQVALLDWVAPGPSTGSGRAGLEAAGDEL---------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LYG4-1", "uniprot_id": "CR3LB_DANRE", "id": "Q1LYG4-1", "name": "Cyclic AMP-responsive element-binding protein 3-like protein 3-B", "aln": "MDHYSDQGG-----------DGIELLDLLFDKNDGILRYENMGQQNNQLWPVQDPHMMMTPQGNEDFFNALIGGSDSVSGSPVWSPSPSDSGISEDPHSDHIDSPPPNAS--PPMEPHIVVSQTQHSLNINFPFDFNGWETG-----FLPDQSGGTQCASETPQ-----------AQQTTGFPLTVKDLLLSGTPEPAAKVSQQS----------YQELILTEDEKRLLAKEGMTLPNQFPLTKYEERILKKIRRKIRNKQSAQESRKKKKEYIDGLESRMAACSAHNHELQRKVFQLEKCNISLMEQLRRLQALVMNGSNKPVQAGTCVLVLLLSFTLILLPNLKPFTDTKVSQHGDFSPMRVQSRSLHNLQSSRVLRNLDHPYSMTENAKILPRFPEDKTMEEIASLLGRLHRRPQFTEYDPESHNHS--FDQHDEHHHGDPITGHVATVTLNPRRGSRRSPHADDM---------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: * *.:*:****** :***** ::.: .:: : :: ..::*:..::* .** ..**:*** ******** ** *:** ... . . : .. .: . . : : * : :. . .. ****:***** : : ***:******:******:***.*:********:*****************************.**:**:*:*:******::*** *:**:***::***:*::.:.*..::***: ******.**:**.:.** .*... *** *:** **:*** :*** : . . : : .: * : . : : * .* : : : * .: . **. . . . :: ", "identical_positions": 165, "similar_positions": 116, "identity": "33.67%" }, { "cls_id": "homologset.agr.RGD:1308153", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z9I4-1", "uniprot_id": "D3Z9I4_RAT", "id": "D3Z9I4-1", "name": "DNA replication complex GINS protein PSF3", "aln": "MSEAYFPVESGALGPEENFLSLDDIVMSQEKLPVRVETPMPRLGAFFLERGAGAEADHPLPQGTKLELPLWLAKGLFDNKR----------RILSVELPKMYQEGWRTVFSADANVVDLHKMGPHFYGFGSQLLHFDSPENSDISQSLLQTFIGRFRRIMDSSQNSYNEDTSALVARLDETERGLFQIGQKGLNDFQSWEKGQASQITASSLVQNYKK-RKFTNLED--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CY94-1", "uniprot_id": "PSF3_MOUSE", "id": "Q9CY94-1", "name": "DNA replication complex GINS protein PSF3", "aln": "MSEAYFPVESGALGPEENFLSLDDILMSQEKLPVRVETPMPRLGAFFLERGAGSEPDHPLPQGTKLELPLWLAKGLFDHKR----------RILSVELPKMYQEGWRTVFSADANVVDLHKMGPHFYGFGSQLLHFDSPENADISQSLLKTFIGRFRRIMDSSQNSYNEDTSALVARLDETERGLFQIGQRSLNDFQSWEKGQASQITASSLVQNYKK-RKFTNMED--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BRX5-1", "uniprot_id": "PSF3_HUMAN", "id": "Q9BRX5-1", "name": "DNA replication complex GINS protein PSF3", "aln": "MSEAYFRVESGALGPEENFLSLDDILMSHEKLPVRTETAMPRLGAFFLERSAGAETDNAVPQGSKLELPLWLAKGLFDNKR----------RILSVELPKIYQEGWRTVFSADPNVVDLHKMGPHFYGFGSQLLHFDSPENADISQSLLQTFIGRFRRIMDSSQNAYNEDTSALVARLDEMERGLFQTGQKGLNDFQCWEKGQASQITASNLVQNYKK-RKFTDMED--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W2V7-1", "uniprot_id": "Q9W2V7_DROME", "id": "Q9W2V7-1", "name": "DNA replication complex GINS protein PSF3", "aln": "---------MNGMNYFPNYYSIEDIFVTQEKVECRVNTKLQRMG--FLDSGAESDD---LEPGRTVNLPLWYIKELKVNN-----------AYFTVAVPDIYRNVHKAVCEAETTHIELGRLHPYFYEFGRYLTPYDR--NHVIGRIIFETLRQRVRHLLDISKS--DGQAAKAEHRLDNIEAKLHEAGVRTNSQYIEWLQMTGNKIRTSELVEEHQKKRRRADRSDDEGDALPNSKRATL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12146-1", "uniprot_id": "PSF3_YEAST", "id": "Q12146-1", "name": "DNA replication complex GINS protein PSF3", "aln": "----------------MGYYDIDDVLADGTEFPCKFQYDIPGLG--YLEN----NPGRPITKNTKLSLPLWLARILAIVGGDEALVDEEPVPFVELLPPDMFSTKVMNAIKTDPVALDLHSINSHFFSLAIKWIMLFS--EKELANVVSELLLQRAQELN--------HHASSLSIDLNADSTGKNSANTNIATSTFLLKLEEMEKEIYKKSHESYKDTKRWMFKK---------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: .::*:. :. : : : :* :*: : : . .:.**** : * . : *.:: . .::. ::* : .:*: :. : :.. : : : * :.: .:: *: . . . . .. .: .. :.::. :: . ", "identical_positions": 13, "similar_positions": 72, "identity": "5.39%" }, { "cls_id": "homologset.agr.RGD:1308154", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4ADL7-1", "uniprot_id": "D4ADL7_RAT", "id": "D4ADL7-1", "name": "Xyloside xylosyltransferase 1", "aln": "MAPPFRCPRSRLAPGSAVPPPLWPPPAAGLRALECCFEWARLLGRRLRRMDLLRGGAACARAMARLGAVRSHYCALLLAAALAVCAFY-------------YLGSGRETFSSATKRLKEARAGA---AAPTPPVPELARGSAAPASGAKAKNLEGGLAVPVDYHLLMMFTKAEHNAALQAKARVALRSLLRLAKFEPHEVLNLHFVSEEASREVAKALLRELLPPAAGFKCKVIFHDVAVLTDKLFPVVEAMQKYFSAGSGTYYSDSIFFLSVAMHQIMPKEILRIIQLDLDLKYKTNIRELFEEFDNFLPGAVIGIAREMQPVYRHTFWQFRHENPKTRVGDPPP--------------EGLPGFNSGVMLLNLEAMRQSPLYGHLLEPAWVQQLADKYHFRGHLGDQDFFTMIGMEHPELFHVLDCTWNRQLCTWWRDHGYSDVFPAYFHCEGHVKIYHGNCNTPIPED", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3U4G3-1", "uniprot_id": "XXLT1_MOUSE", "id": "Q3U4G3-1", "name": "Xyloside xylosyltransferase 1", "aln": "-------------------------------------------------MGLLRGGAACARAMARLGALRSHYCALLLAAALAVCAFY-------------YLGSGRETFSSATKRLKEARAGA---AAPTPPAPELARGSAAPASGAKAKSLEGGVVVPVDYHLLMMFTKAEHNAPLQAKARVALSSLLRLAKFEAHEVLNLHFVSEEASREVAKALLRELLPPAAGFKCKVIFHDVAVLTDKLFPVVEAMQKYFSAGSGTYYSDSIFFLSVAMHQIMPKEIPRIIQLDLDLKYKTNIRELFEEFDNFLPGAVIGIAREMQPVYRHTFWQFRHENPKTRVGDPPP--------------EGLPGFNSGVMLLNLEAMRQSPLYSHLLEPSWVQQLADKYHFRGHLGDQDFFTMIGMEHPELFHVLDCTWNRQLCTWWRDHGYSDVFQAYFRCEGHVKIYHGNCNTPIPED", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NBI6-1", "uniprot_id": "XXLT1_HUMAN", "id": "Q8NBI6-1", "name": "Xyloside xylosyltransferase 1", "aln": "-------------------------------------------------MGLLRGGLPCARAMARLGAVRSHYCALLLAAALAVCAFY-------------YLGSGRETFSSATKRLKEARAGAP--AAPSPPALELARGSVAPAPGAKAKSLEGGGAGPVDYHLLMMFTKAEHNAALQAKARVALRSLLRLAKFEAHEVLNLHFVSEEASREVAKGLLRELLPPAAGFKCKVIFHDVAVLTDKLFPIVEAMQKHFSAGLGTYYSDSIFFLSVAMHQIMPKEILQIIQLDLDLKFKTNIRELFEEFDSFLPGAIIGIAREMQPVYRHTFWQFRHENPQTRVGGPPP--------------EGLPGFNSGVMLLNLEAMRQSPLYSRLLEPAQVQQLADKYHFRGHLGDQDFFTMIGMEHPKLFHVLDCTWNRQLCTWWRDHGYSDVFEAYFRCEGHVKIYHGNCNTPIPED", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F9V4-1", "uniprot_id": "E7F9V4_DANRE", "id": "E7F9V4-1", "name": "", "aln": "-------------------------------------------------MGVLR---VLWGIMGRISMFRSYQIVLLLAAALAVVAFY-------------YFGSEKQNFSSTTKRIKETQASHNSNRDDADLSIDIQPGHLESRPGAGAE-LEGK---PKRFHALMMFTKVDKSLSLQQKFQTAMRSMVKHGRFLEDEILVLHYVSDLGSQEFGEKMLPELLLDAS-FQYEVVFHNVDTLTEKLFPIVEAMQKHFSAGSGAYYSDAIFFLSVAMHRIMPAELKRIVQLDLDLKFRSNIRDLFQEFNHFPSDAVIGIAREMQPVYRHTFWQYRKENPKSRVGDPPP--------------DGLPGFNSGVMLLNLDSMRRSTVYNQLLEPERVARLADKYHFRGHLGDQDFFTMIGMEHTELFYPLTCGWNRQLCTWWRDHGYGDVFQLYYHCDGPVHIHHGNCNTPIPDD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W1D1-1", "uniprot_id": "Q9W1D1_DROME", "id": "Q9W1D1-1", "name": "Xyloside xylosyltransferase 1", "aln": "---MAKNSFKTLISQKHKTFPADLNMYGMKCKSQLLEDQENVTLIINRRNSIRQKPKSWAWTLLRCRWQKKLVLLLIFICVCVLIVFANTHLLVRGNILSAFLSSRLNKHSHAEK--QEARYPDIPATTPSVPPVLRPTHYLLNYSSTQLELSSHLNGLSSDYNIFVIYTRENY--HLNLKFDLFAHSLLKHT----SAQLHLHVITDSESQPSVLEILQRQIRRFR-RTVIYTIYDVKVCSSIIQDIAAKLSPYFSSTPNSYYSDSLFFLSLGLHRIADRSLNRAILLDCDIVFRSDVRLLFNEFDNFLPHQLYGLAPELTPVYRHILYRYRVRYPKTSFGNPYYPINNEGGNQHSRVHHGYPGLNSGVVLLLLNRIRNSKSYLEKLTHSEVHTLVAKYSFKGHLGDQDFFTLLGYEYPNLIYRLDCIWNRQLCTWWKDHGYSQIFDAYFRCEGNIKMYHGNCNTRIPE-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: : : * :. *:: .. .: .* ::.* :..* : * :*:: : ..: : . . :: ::::*: : *: * *::: * ** ::: *: :* . : :::* . :. : :. :. :**: .:****::****:.:*:* .: : : ** *: :::::* **:**: * . : *:* *: ***** ::::* . *:: .*.* .* **:****:** *: :*.* * . * * *. ** *:**********::* *:.:*:: * * *********:****.::* *::*:* ::::****** **: ", "identical_positions": 109, "similar_positions": 123, "identity": "23.14%" }, { "cls_id": "homologset.agr.RGD:1308155", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4ADK7-1", "uniprot_id": "D4ADK7_RAT", "id": "D4ADK7-1", "name": "Melanotransferrin", "aln": "MRLLSVTFWLLLSLRTVLC----------VMEMQWCTISDPEQQKCKDMSKAFQG-----AGIQPSLLCVQGTSTDHCVQLIKDQK-ADAITLDGGAIYQAGKEYGLKPVVGEVYDQDIGTSYYAVAVVRR---NSNVTINTLKGVKSCHTGINRTVGWNVPVGYLVETGHLSVMGCD-VLKAVGDYFGGSCVPGAGETSH------SESLCRLCRGDSSGHNVCDKSPLERYYDYSGAFRCLAEGAGDVAFVKHSTVLENTDGKTLPSWGKALMSQDFQLLCRDGSRADITEWRRCHLAKVPAHAVVVRDDMDGG----------LIFRLLNEGQLLFSHEDSS------------------------------------------------------------FQMFSSKAYGQKNLLFKDST--LELVPIATQNYESWLGQEYLHAMKGLLCDPNRLPHYLRWCVLSVPEIQKCGDMAVAFSRQSLKPEIQCVSAESPEHCMQQIQAGHIDAVTLRGEDIYRAGKAYGLVPAAGELYAEEDRSNSYFVVAVVRRDSSYSFTLDELRSKRSCHPGLGSPAGWEVPIGSLIQRGFIRPKDCDVLTAVSEFFNASCVPVNNPKNYPS-----SLCALCVGDEKGRNKCVGSSQERYYGYSGAFRCLVENAGDVAFLKHTTVFENTNGHNPEPWASHLRWQDYELLCPNGARAEVDQFQACNLAQMPSHAVMVHP-----DTNIFTVYGLLDKAQDLFGDDHNKNGFQMFDSSKYHSQDLLFKDATVRAVPVR-EKTTYLDWLGPDYVVALEGMLSQQCSGAGAAVHRVPPPALLLLALAAGLLPRVL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R0R1-1", "uniprot_id": "TRFM_MOUSE", "id": "Q9R0R1-1", "name": "Melanotransferrin", "aln": "MRLLSVTFWLLLSLRTVVC----------VMEVQWCTISDAEQQKCKDMSEAFQG-----AGIRPSLLCVQGNSADHCVQLIKEQK-ADAITLDGGAIYEAGKEHGLKPVVGEVYDQDIGTSYYAVAVVRR---NSNVTINTLKGVKSCHTGINRTVGWNVPVGYLVESGHLSVMGCD-VLKAVGDYFGGSCVPGTGETSH------SESLCRLCRGDSSGHNVCDKSPLERYYDYSGAFRCLAEGAGDVAFVKHSTVLENTDGNTLPSWGKSLMSEDFQLLCRDGSRADITEWRRCHLAKVPAHAVVVRGDMDGG----------LIFQLLNEGQLLFSHEDSS------------------------------------------------------------FQMFSSKAYSQKNLLFKDST--LELVPIATQNYEAWLGQEYLQAMKGLLCDPNRLPHYLRWCVLSAPEIQKCGDMAVAFSRQNLKPEIQCVSAESPEHCMEQIQAGHTDAVTLRGEDIYRAGKVYGLVPAAGELYAEEDRSNSYFVVAVARRDSSYSFTLDELRGKRSCHPYLGSPAGWEVPIGSLIQRGFIRPKDCDVLTAVSQFFNASCVPVNNPKNYPS-----ALCALCVGDEKGRNKCVGSSQERYYGYSGAFRCLVEHAGDVAFVKHTTVFENTNGHNPEPWASHLRWQDYELLCPNGARAEVDQFQACNLAQMPSHAVMVRP-----DTNIFTVYGLLDKAQDLFGDDHNKNGFQMFDSSKYHSQDLLFKDATVRAVPVR-EKTTYLDWLGPDYVVALEGMLSQQCSGAGAAVQRVPLLALLLLTLAAGLLPRVL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P08582-1", "uniprot_id": "TRFM_HUMAN", "id": "P08582-1", "name": "Melanotransferrin", "aln": "MRGPSGALWLLLALRTVLG----------GMEVRWCATSDPEQHKCGNMSEAFRE-----AGIQPSLLCVRGTSADHCVQLIAAQE-ADAITLDGGAIYEAGKEHGLKPVVGEVYDQEVGTSYYAVAVVRR---SSHVTIDTLKGVKSCHTGINRTVGWNVPVGYLVESGRLSVMGCD-VLKAVSDYFGGSCVPGAGETSY------SESLCRLCRGDSSGEGVCDKSPLERYYDYSGAFRCLAEGAGDVAFVKHSTVLENTDGKTLPSWGQALLSQDFELLCRDGSRADVTEWRQCHLARVPAHAVVVRADTDGG----------LIFRLLNEGQRLFSHEGSS------------------------------------------------------------FQMFSSEAYGQKDLLFKDST--SELVPIATQTYEAWLGHEYLHAMKGLLCDPNRLPPYLRWCVLSTPEIQKCGDMAVAFRRQRLKPEIQCVSAKSPQHCMERIQAEQVDAVTLSGEDIYTAGKTYGLVPAAGEHYAPEDSSNSYYVVAVVRRDSSHAFTLDELRGKRSCHAGFGSPAGWDVPVGALIQRGFIRPKDCDVLTAVSEFFNASCVPVNNPKNYPS-----SLCALCVGDEQGRNKCVGNSQERYYGYRGAFRCLVENAGDVAFVRHTTVFDNTNGHNSEPWAAELRSEDYELLCPNGARAEVSQFAACNLAQIPPHAVMVRP-----DTNIFTVYGLLDKAQDLFGDDHNKNGFKMFDSSNYHGQDLLFKDATVRAVPVG-EKTTYRGWLGLDYVAALEGMSSQQCSGAAAPAPGAPLLPLLLPALAARLLPPAL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B3G9-1", "uniprot_id": "A0A8M3B3G9_DANRE", "id": "A0A8M3B3G9-1", "name": "Serotransferrin", "aln": "MDTWTFLSVLLALTHYVSG----------QSTIRWCVISVAEESKCKAMAQAFSS-----ASVRPALKCVLAASKAECAQKLTQKKEVDAFSASAKDIYDIGKLASFKISAGESGSDGKGITYYGVAVVKKT--NAAININNLKGKKSCHTGKNRTAGWNVPLGYLIDSGMMSVMGCN-IPQGVADFFNASCIPGAKDD--------PASLCQQCVGDRTGQFKCDPSNKELYYAYDGAFRCLVEDAGDVAFVKHTTVSENTDGK-GASWAQELQSKDYQLLCRDGTRSPVTDYEKCHLARVPSRGIVIHPDITTS----------VVYNMLTEG-----LQKSG------------------------------------------------------------FSMFSSADFGGENLLFSDTS--TKFIQAGNENYKEWMG-RYYHILKAMDCSQSDIPSQLQWCVLSHGEQQKCADMAVAFKNKNLIPNIQCVYGASVEDCMKKIQNKEADAITLDGGYIYTAGKSYGLIPAVGESYTGDSDGSIYYAVAVLRKSNRDIQRFSDLKGKRSCHTGYGRTAGWNIPMGLLIEKGIIRPQTCQVAQAAGEFFESACVPGADQKDFPE-----NLCKQCIGDSSGQFKCVK-GKDLYDGYDGAFRCLVENHGDVAFVKHSTVFQNTDGNNTDPWAVNLDSREFQLLCSQESRAEVTQFTKCNLARVPSHAVMIRP-----DTNHHIIFGLLDKAQRFFGVNS-ASGFKMFDSKAYEGSDLIFKDSTITLIGVG-ERKTYEEWLGQSY---LDSLIAMECS---ASSTVFSFSSLLLMSIVSSLVSLLAL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VTZ5-1", "uniprot_id": "TRFM_DROME", "id": "Q9VTZ5-1", "name": "Transferrin 2", "aln": "MASSLVFVALVGALCFTLANAQHHYDEHKTTRMVWCTKSQAEQYKCQNLTVAIERDRALFDEVFLNLTCFMAYSADECIHHIDREK-AHITTLDAGDVFTAGRYNSLIPIMQEKLEGG-FADYQSVAVIKKGSLPDLNNLRDMRNKRVCFPWVGSLAGWIVPIHTLQREGGMEVVDCNNQVKTAASYFNNSCAVYSLSDKHNPIGDNSDKLCTLCTGKIPGG---RCSSADPYFGYEGAFKCLLE-KGDVAFLRHSTVNEMLQTTEFKNIAPDT----FELLCRDGRRASINDYRQCNWGQVPADAIVTSSARSFSDRKQYQQFLKRIAELYSDGTRDDQSRQGGQSFNSRNNINDQNAYGQFDNNDPYRTQNQYDQYRSERLDSSFAEERNQQDGTNTSILYEKFRIFESKRYGKPNLLFQDSSRALTVIPEDDQSFTKYLGPAINFIYGIRECP----VPAMTLCVTSENELDKCIKMRTALKAHLLKPELICKKMHSHINCMQFIEAGKADISVFDAGDVYTGGLNYDLVPFMSEVYNLGEPE--YYVVAVAKEDDP-DTELTYLKGKNTCHTGINTAAGWTYPMALFISNGWIRPYGCDSVRAAAEYFTKSCVPGAISNEYNTGVPYDSMCDLCHG--TSYRYCRRDASEEYYGHTGAFRCLVEGGGHVAFMKHTTVMESTGGKRKEWWARNALNDDFELLCTDGTRAEIQDYKRCNLGKVKANAVVTRGGVNYNETQMNAYINLLTYAQQLYGRKEVDAFSFSMFSSPIGHYDLIFQDATRQLQVIPPNKRRYDAYLGSDFMR----ARRITDCYAGASQLALSVGLLLVGSLVAML------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *: . : **. * .*: ** :: *: : * *. . * .* : : :: .. : .. :: *: .: * . * .***::: .: ::. : *.. . .** **: * * :.*:.*: : ...:*. ** : . . .** * *. .* * : *: *.***:** * *****::*:** * : . . . ::****** *: :.::.:*: .:**: .:* . : .: .:* . .. * :*.* :. :***.*:: .: :.: ::* * : ** * * :** .* .*: : * *:: * * .**: *: . * .: . :* .* *.*:* .* * . *:.*** :... : *:.*.:**. . .*** *:. :*..* *** *: *..::* :*** ::: :* * * . * ..: * *: ******** *.***::*:**::.*.*:. : ** . :::***.: :***: :: ***.:: .:**: : :*: .** ** ::* . : *. **:*:*:* : :: * :** .: . *. . **: ::.: * ", "identical_positions": 176, "similar_positions": 218, "identity": "20.75%" }, { "cls_id": "homologset.agr.RGD:1308157", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WTX6-1", "uniprot_id": "CUL1_MOUSE", "id": "Q9WTX6-1", "name": "Cullin-1", "aln": "--MSSNRSQNPHG-LKQIG--LDQIWDDLRAGIQQVYT-RQSMAKSRYMELYTHVYNYCTSVHQSNQARGAGVPPSKSKKGQTPGGAQFVGLELYKRLKEFLKNYLTNLLKDGEDLMDESVLK-FYTQQWEDYRFSSKVLNGICAYLNRHWVRRECDEGRKGIYEIYSLALVTWRDCLFRPLNKQVTNAVLKLIEKERNGETINTRLISGVVQSYVELGLNEDDAFAKGPTLTVYKESFESQFLADTERFYTRESTEFLQQNPVTEYMKKAEARLLEEQ---RRVQ--------VYLHESTQDELARKCEQVLIEKHLEIFHTEFQNLLDADKNEDLGRMYNLVSRIQDGLGELKKLLETHIHNQG------LAAIEKCG-EAALND--------------PKMYVQTVLDVHKKYNALVMSAFNNDAGFVAALDKACGRFINNNAVTKMAQSS----SKSPELLARYCDSLLKKSSKNPEEAELEDTLNQVMVVFKYIEDKDVFQKFYAKMLAKRLVHQNSASDDAEASMISKLKQACGFEYTSKLQRMFQDIGVSKDLNEQFKKHLTNS----EPLDLDFSIQVLSSGSWPFQ-QSCTFALPSELERSYQRFTAFYASRHSGRKLTWLYQLSKGELVTNCFKN---RYTLQASTFQMAILLQYNTEDAYTVQQLTDSTQIKMDILAQVLQILLKSKLLVLEDENANVDEVELKPDTLIKLYLGYKNKKLRVNINVPMKTEQKQ--------------------EQETTHKNIEEDRKLLIQAAIVRIMKMRKVLKHQQLLGEVLTQLSSRFKPRVPVIKKCIDILIEKEYLERVDGEKDTYSYLA-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13616-1", "uniprot_id": "CUL1_HUMAN", "id": "Q13616-1", "name": "Cullin-1", "aln": "--MSSTRSQNPHG-LKQIG--LDQIWDDLRAGIQQVYT-RQSMAKSRYMELYTHVYNYCTSVHQSNQARGAGVPPSKSKKGQTPGGAQFVGLELYKRLKEFLKNYLTNLLKDGEDLMDESVLK-FYTQQWEDYRFSSKVLNGICAYLNRHWVRRECDEGRKGIYEIYSLALVTWRDCLFRPLNKQVTNAVLKLIEKERNGETINTRLISGVVQSYVELGLNEDDAFAKGPTLTVYKESFESQFLADTERFYTRESTEFLQQNPVTEYMKKAEARLLEEQ---RRVQ--------VYLHESTQDELARKCEQVLIEKHLEIFHTEFQNLLDADKNEDLGRMYNLVSRIQDGLGELKKLLETHIHNQG------LAAIEKCG-EAALND--------------PKMYVQTVLDVHKKYNALVMSAFNNDAGFVAALDKACGRFINNNAVTKMAQSS----SKSPELLARYCDSLLKKSSKNPEEAELEDTLNQVMVVFKYIEDKDVFQKFYAKMLAKRLVHQNSASDDAEASMISKLKQACGFEYTSKLQRMFQDIGVSKDLNEQFKKHLTNS----EPLDLDFSIQVLSSGSWPFQ-QSCTFALPSELERSYQRFTAFYASRHSGRKLTWLYQLSKGELVTNCFKN---RYTLQASTFQMAILLQYNTEDAYTVQQLTDSTQIKMDILAQVLQILLKSKLLVLEDENANVDEVELKPDTLIKLYLGYKNKKLRVNINVPMKTEQKQ--------------------EQETTHKNIEEDRKLLIQAAIVRIMKMRKVLKHQQLLGEVLTQLSSRFKPRVPVIKKCIDILIEKEYLERVDGEKDTYSYLA-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I5Y0H0-1", "uniprot_id": "A0A8I5Y0H0_RAT", "id": "A0A8I5Y0H0-1", "name": "Cullin-1", "aln": "--MSSNRSQNPHG-LKQIG--LDQIWDDLRAGIQQVYT-RQSMAKSRYMELYTHVYNYCTSVHQSNQARGAGVPPSKSKKGQTPGGAQFVGLELYKRLKEFLKNYLTNLLKDGEDLMDESVLK-FYTQQWEDYRFSSKVLNGICAYLNRHWVRRECDEGRKGIYEIYSLALVTWRDCLFRPLNKQVTNAVLKLIEKERNGETINTRLISGVVQSYVELGLNEDDAFAKGPTLTVYKESFESQFLADTERFYTRESTEFLQQNPVTEYMKKAEARLLEEQ---RRVQ--------VYLHESTQDELARKCEQVLIEKHLEIFHTEFQNLLDADKNEDLGRMYNLVSRIQDGLGELKKLLETHIHNQG------LAAIEKCG-EAALND--------------PKMYVQTVLDVHKKYNALVMSAFNNDAGFVAALDKACGRFINNNAVTKMAQSS----SKSPELLARYCDSLLKKSSKNPEEAELEDTLNQVMVVFKYIEDKDVFQKFYAKMLAKRLVHQNSASDDAEASMISKLKQACGFEYTSKLQRMFQDIGVSKDLNEQFKKHLTNS----EPLDLDFSIQVLSSGSWPFQ-QSCTFALPSELERSYQRFTAFYASRHSGRKLTWLYQLSKGELVTNCFKN---RYTLQASTFQMAILLQYNTEDAYTVQQLTDSTQIKMDILAQVLQILLKSKLLVLEDENANVDEVELKPDTLIKLYLGYKNKKLRVNINVPMKTEQKQ--------------------EQETTHKNIEEDRKLLIQAAIVRIMKMRKVLKHQQLLGEVLTQLSSRFKPRVPVIKVPPSEAFPRRLPYSPQDVPGRRAQARG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q24311-1", "uniprot_id": "CUL1_DROME", "id": "Q24311-1", "name": "Cullin homolog 1", "aln": "----MNRSGNSQTTQKLVN--LDDIWSELVEGIMQVFEHEKSLTRSQYMRFYTHVYDYCTSVSAAPSGRSSGK----------TGGAQLVGKKLYDRLEQFLKSYLSELLTKFKAISGEEVLLSRYTKQWKSYQFSSTVLDGICNYLNRNWVKRECEEGQKGIYKIYRLALVAWKGHLFQVLNEPVTKAVLKSIEEERQGKLINRSLVRDVIECYVELSFNEEDTDAEQQKLSVYKQNFENKFIADTSAFYEKESDAFLSTNTVTEYLKHVENRLEEET---QRVRGFNSKNGLSYLHETTADVLKSTCEEVLIEKHLKIFHTEFQNLLNADRNDDLKRMYSLVALSSKNLTDLKSILENHILHQG------TEAIAKCCTTDAAND--------------PKTYVQTILDVHKKYNALVLTAFNNDNGFVAALDKACGKFINSNVVT-IANSA----SKSPELLAKYCDLLLKKSSKNPEDKELEDNLNQVMVVFKYIEDKDVFQKYYSKMLAKRLVNHTSASDDAEAMMISKLKQTCGYEYTVKLQRMFQDIGVSKDLNSYFKQYLAEKN---LTMEIDFGIEVLSSGSWPFQ-LSNNFLLPSELERSVRQFNEFYAARHSGRKLNWLYQMCKGELIMNVNRNNSSTYTLQASTFQMSVLLQFNDQLSFTVQQLQDNTQTQQENLIQVLQILLKAKVLTSSD-----NENSLTPESTVELFLDYKNKKRRININQPLKTELKV--------------------EQETVHKHIEEDRKLLIQAAIVRIMKMRKRLNHTNLISEVLNQLSTRFKPKVPVIKKCIDILIEKEYLERMEGHKDTYSYLA-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12018-1", "uniprot_id": "CDC53_YEAST", "id": "Q12018-1", "name": "Cell division control protein 53", "aln": "MSETLPRSDDLEATWNFIEPGINQILGNEKNQASTSKRVYKILSPTMYMEVYTAIYNYCVNKSRSSGHFSTDS--------RTGQSTILVGSEIYEKLKNYLKNYILNFKQ-----SNSETFLQFYVKRWKRFTIGAIFLNHAFDYMNRYWVQKERSDGKRHIFDVNTLCLMTWKEVMFDPSKDVLINELLDQVTLGREGQIIQRSNISTAIKSLVALGIDPQD--LKKLNLNVYIQVFEKPFLKKTQEYYTQYTNDYLEKHSVTEYIFEAHEIIKREEKAMT-----------IYWDDHTKKPLSMALNKVLITDHIEKLENEFVVLLDARDIEKITSLYALIRRDFTLIPRMASVFENYVKKTGENEISSLLAMHKHNIMKNENANPKKLALMTAHSLSPKDYIKKLLEVHDIFSKIFNESFPDDIPLAKALDNACGAFININEFALPAGSPKSATSKTSEMLAKYSDILLKKATKPEVASDMSD--EDIITIFKYLTDKDAFETHYRRLFAKRLIHGTSTSAEDEENIIQRLQAANSMEYTGKITKMFQDIRLSKILEDDFAVALKNEPDYSKAKYPDLQPFVLAENMWPFSYQEVEFKLPKELVPSHEKLKESYSQKHNGRILKWLWPLCRGELKADIGKPGRMPFNFTVTLFQMAILLLYNDADVLTLENIQEGTSLTIQHIAAAMVPFIKFKLIQQVPPG---LDALVKPETQFKLSRPYKALKTNINFASGVKNDILQSLSGGGHDNHGNKLGNKRLTEDERIEKELNTERQIFLEACIVRIMKAKRNLPHTTLVNECIAQSHQRFNAKVSMVKRAIDSLIQKGYLQRGDD-GESYAYLA-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** : . : : :::* .: : :: : **..** :*:**.. : .:. .: :** ::*.:*:::**.*: :: ....: *.::*: : :.: .*: *:** **::* .:*:: *:.: *.*::*: :* :. : : :*. : *:*: *: : .::. * *.:: :* : .*.** : **. *: .*. :* : : :*. :.****: ... : .* * .: * . * ::*** .*:: :..** **:* :.: :* *: : : .::*.:: : * *: * * ** *::.:*:**. :. :. :* :* :. ***:*** *** * .: * *. **:.*:**:*.* ****::* ::.* ::::.:***: ***.*:..* :::****:: .*:* : * :*.:*: : . *** *: :***** :** *:. * * :. . *: **:.. ***. . * **.** * .::. *: :*.** *.**: :.:*** : : :.: .: ***::** :* *:::: :.*. : : .: ::* *:: : :.*:: .:* ** * .:*: :*.: *:* .*.:: :*:::::*.****** :: * * *:.* : * **:.:*.::* . : : :. : ", "identical_positions": 195, "similar_positions": 281, "identity": "23.0%" }, { "cls_id": "homologset.agr.RGD:1308158", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q3SWT1-1", "uniprot_id": "SOSB1_RAT", "id": "Q3SWT1-1", "name": "SOSS complex subunit B1", "aln": "-MTTETF-VKDIKPGLKNLNLIFIVLETGRVTKTKDGHEVRTCKVADKTGSINISVWDDVGNLIQPGDIIRLTKGYASVFKGCLTLYTGRGGDLQKIGEFCMVYSEVPNFSEPNPEYNTQQASNKSVQN-DSSPTAPQATTGPPAASPASESQNGNGLSTQPGPVGGPHPSHAPSHPPSTRITRSQPNHTPSGPPGPSSSPVSNGKETRRSSKR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R2Y9-1", "uniprot_id": "SOSB1_MOUSE", "id": "Q8R2Y9-1", "name": "SOSS complex subunit B1", "aln": "-MTTETF-VKDIKPGLKNLNLIFIVLETGRVTKTKDGHEVRTCKVADKTGSINISVWDDVGNLIQPGDIIRLTKGYASVFKGCLTLYTGRGGDLQKIGEFCMVYSEVPNFSEPNPEYNTQQAPNKSVQNNDNSPTAPQATTGPPAASPASENQNGNGLSTQLGPVGGPHPSHTPSHPPSTRITRSQPNHTPSGPPGPSSNPVSNGKETRRSSKR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BQ15-1", "uniprot_id": "SOSB1_HUMAN", "id": "Q9BQ15-1", "name": "SOSS complex subunit B1", "aln": "-MTTETF-VKDIKPGLKNLNLIFIVLETGRVTKTKDGHEVRTCKVADKTGSINISVWDDVGNLIQPGDIIRLTKGYASVFKGCLTLYTGRGGDLQKIGEFCMVYSEVPNFSEPNPEYSTQQAPNKAVQN-DSNPSASQPTTGPSAASPASENQNGNGLSAPPGPGGGPHPPHTPSHPPSTRITRSQPNHTPAGPPGPSSNPVSNGKETRRSSKR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BK34-1", "uniprot_id": "A0A8M2BK34_DANRE", "id": "A0A8M2BK34-1", "name": "", "aln": "-MSAETH-VKDIKPGLKNLNVIFIVLETGRVTKTKDGHEVRTCKVADKTGSISISVWDEVGGLIQAGDIIRLTKGYASVFKGCLTLYTGRGGELQKIGEFCMVYSEVPNFSEPNPEYLTQT--NKTGLN---DQSNMNSSTG---ATTGTDTPNGNGVNSQAS--GNSSNPQSSGRANSGNGNRS----TPSPAAGGTS--VSNGKETRRTLKR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VM17-1", "uniprot_id": "SOSSB_DROME", "id": "Q9VM17-1", "name": "SOSS complex subunit B homolog", "aln": "MYNVECIPIKDIKPGLKNINVIFIVLEVGVATVTKENREVRNFKVGDPTACINVSIWDEPGKLIAPGDIVRLTKGYASIWRHCLTLYSGKNGEVFKIGEYCMVFNESVNMSEP------KRAEQQAVANPAATPAGLPAGGG----APGLPAKGGATGIPQPAVAAAPGAPATQSAVTTAPAAAPAIAPQTTTKPGTRGGRGGGGRGGLKGERR", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..* :*********:*:******.* .* **:.:***. **.* *..*.:*:**: * ** .***:********::: *****:*:.*:: ****:***:.* *:*** : ::: * : . * :.. .* . . . . . : . : . .: .* . ..*: : :*", "identical_positions": 71, "similar_positions": 60, "identity": "33.18%" }, { "cls_id": "homologset.agr.RGD:1308159", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "B6RHI6-1", "uniprot_id": "B6RHI6_RAT", "id": "B6RHI6-1", "name": "E3 ubiquitin-protein ligase LNX", "aln": "MNQPD------------LADDPDPSPEPLCVVCGQNHSPEENHFYTYTEDVDDDLVCHICLQALLDPLDTPCGHTYCTLCLTNFLVEKDFCPVDRKPVVLQHCKKSNILVNKLLNKLLVNCPFTEHCSEVLQRCNLQYHFQTSCKGASHYGLTKDRKRRSQDG-CPDGCASLTATTLSPEVSAAATISLMTDEPGLDNPAYTSSVEDGE---PVTNPSDTGRSNRTRARPFERSTMRSRSFKKINRALSALRRTKSGSAVANHADQGRDNSENDTVPEV-----FPRLFHLIPDGEITSIKINRVDPNESLSIRLVGGSETPLVHIIIQHIYRDGVIARDGRLLPGDIILKVNGMDISNVPHNYAVRLLRQPCQVLRLTVLREQKFRSRSNAPAPDSYGP------RDDSFHVILNKSSPEEQLGIKLVRRVDEPGVFIFNVLNGGVADRHGQLEENDRVLAINGHDLRFGSPESAAHLIQASERRVHLVVSRQVRQPSPDIFQEAGCISNGQQSPVSGERSTSSK---PAATCHEKVVSVQKDPNESLGMTVGGGASHREWDLPIYVISVEPGGVISRDGRIKTGDILLNVNGIELTEVSRTEAVAILKSTPSSVVLKALEVKE-QETQEDCS-----PAALDSN----HNVTPPGD-WSPSWVMWLELPQYLYNCKDVILRRNTAGSLGFCIVGGYEEYSGNQPFFIKSIVEGTPAYNDGRIRCGDILLAVNGRSTSGMMHACLARMLKELKGKITLTIASWPGTFL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70263-1", "uniprot_id": "LNX1_MOUSE", "id": "O70263-1", "name": "E3 ubiquitin-protein ligase LNX", "aln": "MNQPD------------LADDPDPSPEPLCIVCGQNHSPEENHFYTYTEDVDDDLICHICLQALLDPLDTPCGHTYCTLCLTNFLVEKDFCPVDRKPVVLQHCKKSSILVNKLLNKLLVTCPFTEHCTEVLQRCDLQHHFQTSCKGASHYGLTKDRKRRSQDG-CPDGCASLMATTLSPEVSAAATISLMTDEPGLDNPAYVSSVEDGE---PVANSSDSGRSNRTRARPFERSTMRSRSFKKINRALSALRRTKSGSVVANHVDQGRDNSENTTVPEV-----FPRLFHLIPDGEITSIKINRADPSESLSIRLVGGSETPLVHIIIQHIYRDGVIARDGRLLPGDIILKVNGMDISNVPHNYAVRLLRQPCQVLRLTVLREQKFRSRSNAHVPDSYGP------RDDSFHVILNKSSPEEQLGIKLVRRVDEPGVFIFNVLNGGVADRHGQLEENDRVLAINGHDLRFGSPESAAHLIQASERRVHLVVSRQVRQSSPDIFQEAGWISNGQQSPGPGERNTASK---PAATCHEKVVSVWKDPSESLGMTVGGGASHREWDLPIYVISVEPGGVISRDGRIKTGDILLNVNGIELTEVSRTEAVAILKSAPSSVVLKALEVKE-QEAQEDCS-----PAALDSN----HNVTPPGD-WSPSWVMWLELPQYLCNCKDVILRRNTAGSLGFCIVGGYEEYSGNKPFFIKSIVEGTPAYNDGRIRCGDILLAVNGRSTSGMIHACLARMLKELKGRITLTIASWPGTFL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TBB1-1", "uniprot_id": "LNX1_HUMAN", "id": "Q8TBB1-1", "name": "E3 ubiquitin-protein ligase LNX", "aln": "MNQPE------------SANDP----EPLCAVCGQAHSLEENHFYSYPEEVDDDLICHICLQALLDPLDTPCGHTYCTLCLTNFLVEKDFCPMDRKPLVLQHCKKSSILVNKLLNKLLVTCPFREHCTQVLQRCDLEHHFQTSCKGASHYGLTKDRKRRSQDG-CPDGCASLTATAPSPEVSAAATISLMTDEPGLDNPAYVSSAEDGQ---PAISPVDSGRSNRTRARPFERSTIRSRSFKKINRALSVLRRTKSGSAVANHADQGRENSENTTAPEV-----FPRLYHLIPDGEITSIKINRVDPSESLSIRLVGGSETPLVHIIIQHIYRDGVIARDGRLLPGDIILKVNGMDISNVPHNYAVRLLRQPCQVLWLTVMREQKFRSRNNGQAPDAYRP------RDDSFHVILNKSSPEEQLGIKLVRKVDEPGVFIFNVLDGGVAYRHGQLEENDRVLAINGHDLRYGSPESAAHLIQASERRVHLVVSRQVRQRSPDIFQEAGWNSNGSWSPGPGERSNTPKPLHPTITCHEKVVNIQKDPGESLGMTVAGGASHREWDLPIYVISVEPGGVISRDGRIKTGDILLNVDGVELTEVSRSEAVALLKRTSSSIVLKALEVKE-YEPQEDCSS----PAALDSN----HNMAPPSD-WSPSWVMWLELPRCLYNCKDIVLRRNTAGSLGFCIVGGYEEYNGNKPFFIKSIVEGTPAYNDGRIRCGDILLAVNGRSTSGMIHACLARLLKELKGRITLTIVSWPGTFL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B7L4-1", "uniprot_id": "A0A8M2B7L4_DANRE", "id": "A0A8M2B7L4-1", "name": "", "aln": "MSDQEEAGAVAMPVCGATGVTPTAPPPDLCHICGQRHLQEENHEYTYKEDVDDDLMCHICLQPLIRPLDTPCGHTYCQECLTNFLLESDFCPVDRTPLMLQKCRKSSLLVHKLLDKLMVSCPFADHCTEVMPRGEMEGHIRCRCKGASHYGLSAERKRRSQEGDCTDSTSELTLAALPGEGCPSSAIALLSDEPGLVNPAYEPSVEDNSQSGSTTSLAARSGSRKSEYRNFDRTSVRSRSFRRLNRAFSVLRRTKSGTAVANDTTEERDNLRNANIPAEGELFALPQLHHLIPDGEVTSIKITRADPCEPLAISIVGGNETPLVRILIQDIYREGVIARDGRLLPGDMILKVNGIDISNVPHCYAVAALKQPCTLLRLTVLREQRHRYRSHHHSPTEAFPAHTATIRDDSLHVVLVKRAPDEQLGIKLVRRPDEHGVFIFHLLEGGLAARDGRLRVDDRVLAINGHDLRYGAPEHAALLIQASEDRVHFIVSRQTHIPAPDILQEAPWNMEGPPPYSPVDIEHTLLDSCQKPACYEKTVTLLKEPHDSLGMTVAGGMSSRGWDLPVYVTNVDPNGVVGQEGSIRKGDILLNVNGVDLTGVTRSEAVANLKNTSSPVVLQVLEMRPPNESSLDCMPPLHSPCALSPSSPGDVKLPPPNDDYAPLWVSWLQLPRHLYCCKDIVLRRSTSGSLGFSIVGGQEELNCNQSFFIRSIVEGTPAYNDGRIRCGDILLEVNGKSTWGMTHTALVRLLKELRGRITLTIVSWPGSLL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.: : . * ** :*** * **** *:* *:*****:******.*: *********** ******:*.****:**.*::**:*:**.:**:***:**:*.*** :**::*: * ::: *:: *********: :******:* *.*. :.* :: . * ..:::*:*::***** **** .*.**.. .. . . *.::. * *:*:::*****:::***:*.*******:.***.. : *:* .* . * :*:*.*******:*****.*.** *.*:* :***.*****:*:**.***:*************:******:******* *** *:*** :* ***:***:.* *.: * * ****:**:* * :*:*********: ** *****::*:**:* *.*:*. :************:*:** ** ****** ***::****.: :***:*** :* . . : . : :*:**.*.: *:* :******.** * * ****:** .*:*.**:.::* *:.*******:*::** *:*:**** ** :.*.:**:.**:: *.. ** *.**... ::.**.* ::* ** **:**: * ***::***.*:*****.**** ** . *:.***:********************* ***:** ** *:.*.*:****:*:*****.****::*", "identical_positions": 417, "similar_positions": 194, "identity": "54.23%" }, { "cls_id": "homologset.agr.RGD:1308160", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CDV0-1", "uniprot_id": "CC178_MOUSE", "id": "Q8CDV0-1", "name": "Coiled-coil domain-containing protein 178", "aln": "MPENEKEPAQPTTNEDALDTGKTCLQIKELKDKERALMLAENARMQGLSEFFFSRHEDKRLYESKSTNTEDVNKAIYFSYPSRRHSCTLVNIPKPCVNKMISHIEDVESKIQEHLTQFEASFEEWT--SVTKDKEAGLDVSAPEKQVHPEKGKDEKCPELKKRMETLLSEAIHLIKSLETDRAEAEQALKQHKSRKKKISMKIDSWSIWKLQELPLAVQKEHENFSKINAELRSYLEDIALKVEQLQERKEKLEKANAKLQVDIDYMASHSVLLEKKRKQELGCLKERYHKKFEVMEKFRAIHEELKESVDKCEGAKARLKNMKVENEREIQEELINATSYEKELDKLSVLDAHYTTSIETVNLDIEGDEEAMNEVLRETQSTTNELENLKKTVDDLKRLFDQYCWRQRKYENEYLEAFSNFYSLKKTWDIELSNVSKDAKDLTIVYEAQSEENKRIQSEIQSITDDIEESIKKTAEMEEEVHTFVEMKMKNNNYLKQLYKQAYQVGAVYHLSRHKTEELEDKLADLKRIFKGREELLKKLTRGDIATGIEIQKRLYAIEETQFIEMQEFIRRQVLYNMALLEVEEQLKELEAEAVRIRYLHRQHSKMLHNIRKRKERVKKNVDATKKKLLKKSKKSRMELTRTEGKRSIIHEEIEIARGQTVALHEKCIELSKEIRIMNLERTNYEERLKKLQEEFFKLQFDREHVHGVYDHLMREKQYCEERIFEEERRFRRLIDMRKNTLKNIRKCQDDLLEENLRLAKEYQSAQLIFLKEKESYFNGYDRLLSLNFSLSDKKKLCQLQKRLDQKWQEYFRLMILFNKTKLAKFQGDSQNSIQKILAVQEESSSLMQHILDFFKSFPNSSCGEDD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1M3U7-1", "uniprot_id": "F1M3U7_RAT", "id": "F1M3U7-1", "name": "", "aln": "MPENEKNAAQPSTNEDTSKTGRTCLQIKELKDKARALMIAEHARMQGLSEFFFSKHDDKTLYETKSTNTEEVNKGIYFSYPSRRHSCSLVNFPKPCVSKMIAHIEDVECKIQEHLKQFEASFEEWT--SATKDKKEDLDISASAQKIPPGKAKDVKCPELKKRMETLLSEAIHLVKSLETDRAEAEQALRQQKSRKNRISMKIDSWSIWKLQELPVAVQKEHEAFSKEIAELRNHLKDLRNTADQLQEQTDMLEQANSKVQADIDYMISHSVLLEKKRKQELELLRKRYQKKFEVMEQFRALHEELKDSVDQIENAKIRLKRMKEEDERELLKDLTTAASYDKELDKLSNLDDHYTTSIESVNQDIEEDEEVVSEVLRETQSTSNELANLMRMIEDLKRQFDQYCWIQRKYEQEYTEALNNYYSAKNTWDIELSNITKDFNNISTVYVETLEENKRLKYEIDNITEEIGESIRKRAELEDEIHSFREMKTRNNNYLKHLYKQSYHVGAVYHIARHKTDELEDKLAEVRRKFKVREDFLKRLIRSHIATGIEVQKRLYSVEESQFAEMQEYIRRKVLYNAALLEVQEPLKEFEREAERIRNIHREHAKMVHDIRRRKERVKRKVEATKKKLQKKSKKSLKELTKTEGKGTMIHQEIEIAKTKTFVFHEKSKELSKEIMIMDLERKSFEEKLVKLQEEFMKLRFDREHIHGVFDHILRERQRCEERIFDEERRFKRLTEMRKDTLENILERQSDLLDENLRLAKEYQNTQMLFLKEKEAYFNGYDRLLSLNSSVSDKKKLCQLQRKLGQKWQEYFRLLILFNQSKLAKFQGDSQNSIQKIFVVQEESSSLIQHILDFFQTLPTSPCEEDD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5BJE1-1", "uniprot_id": "CC178_HUMAN", "id": "Q5BJE1-1", "name": "Coiled-coil domain-containing protein 178", "aln": "MTEN-KTVSSSSTRDDQTNIGLTCQEVKALREKAWSRTNEGNAMSQSLVLYGASKENSEGFHESKMTNTEGVNKGIYFSYPCRRHSCAVVNIPAPCVNKMISHIQDVESKIQEHLKRFETSFEEWSRTSSTKDLKEDWSVTTPVKEVKPGEKRDEKCPELKQEMETLLSEAIRLIKSLETDRADAEEALKQQRSRKNMINMKIDSWSVWKLQELPLAVQKEHEAYLSDVIELQWHLEDKANQLQHFEKQKTELEEANAKIQADIDYMNEHGPLLDSKQNQELQDLKNHYKKKMEVMDLHRKVNEELEEALEACENARLKAQQIKEEIDKDIYQDEKTIEAYKREIYQLNSLFDHYSSSVINVNTNIEEKEEEVTEAIRETKSSKNELHSLSKMLEDLRRVYDQLTWKQKSHENQYLEAVNDFYAAKKTWDIELSDVAKDFSAISLACTKLTEDNKKLEIDINKITVKTNESIRKKSKYESEIKYLTIMKLKNDKHLKNIYKEAYRIGTLFHLTKHKTDEMEDKIAEVRRKFKGREEFLKKLTQGEVAAGMVLQKKLYSIYEVQALERKELIKNRAICAMSLAELQEPLLQLEDEAERIRSLDKEHSVMLNNIIDQKDLIRRKVGKVKKKLRKKGKKTLDALIETESKRSAIFKDLEATKSKTMIFYAKINELNEELKAKEEEKKSFDQTLEILKNKFITMRFKREHAQTVFDHYMQEKKDCEERIFEEDQRFRVLLAVRQKTLQDTQKIIADSLEENLRLAQEYQQLQITFLKEKDNYFNIYDKQLSLDTSIRDKKQLCQLQRRMHTLWQEHFKLVVLFSQMRLANFQTDSQESIQKILAVQEESSNLMQHILGFFQTLTDGTCENDG", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.** * :..:*.:* . * ** ::* *::* : :* *.* : *:.:.: ::*:* **** ***.******.*****::**:* ***.***:**:***.******.:**:*****: * *** : . .:::. ::: * : :* ******:.*********:*:********:**:**:*::***: *.*******:*******:******* : . **: :*:* ::::::. **:**:*:*.***** .*. **:.*::*** *:::*:**:***: .* ::***::::: *.*: : :.:* * :::: :: . :*.:*: :*. * **::*: .** :** .** :.*.:***:*:.*** .* : ::**:* :** * *:.:*::* **..::*: *:*******:::** . :: . *:**::: :*:.** . ***:* :: *.*:: : ** :*:::**::**::*::*:::*:::***:*:***:*:::* ** **::**:* :..:*:*: :**:**:: * * * :* *:.:.: :* *::* * ::* ** *** :.::*: *:::* :*: ::::* .**** **.**: * .**.* : *.:::* :: :*. :: * **.:*: : *:..::: * *:::*:.::*.*** : *:** ::*:: ******:*::**: * :*:.**:: : * *:******:***. *: *****: *** **: ***: *: ***:*****::: ***:*:*::**.: :**:** ***:*****:.******.*:****.**:::. ..* :*.", "identical_positions": 380, "similar_positions": 313, "identity": "43.78%" }, { "cls_id": "homologset.agr.RGD:1308161", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CZ83-1", "uniprot_id": "RM55_MOUSE", "id": "Q9CZ83-1", "name": "Large ribosomal subunit protein mL55", "aln": "-MPLAILLSLLRHCGVRAALPTPRHLHTSPWRADCSRASLTRLRRQAYARLYPVLLVKQDGSTIHIRYREPRRMLAMPLDLDALSPEERRARFRKREAQLQQKREEEPEVVDSFDTERYKQFWTKTKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZF99-1", "uniprot_id": "D3ZF99_RAT", "id": "D3ZF99-1", "name": "", "aln": "-MPLGSLLGLLRHCGVRAAFPAPCHLHTSPWRADCSRASLTRLRRQAYARLYPVLLVKQDGSTIHIRYREPRRMLAMPLDLDALSPEERRARFRKREAQLQQKREEEPEMVDSFDTERYKRFWTKTKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7Z7F7-1", "uniprot_id": "RM55_HUMAN", "id": "Q7Z7F7-1", "name": "Large ribosomal subunit protein mL55", "aln": "MAAVGSLLGRLRQSTVKATGPALRRLHTSSWRADSSRASLTRVHRQAYARLYPVLLVKQDGSTIHIRYREPRRMLAMPIDLDTLSPEERRARLRKREAQLQSRKEYEQELSDDLHVERYRQFWTRTKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VE04-1", "uniprot_id": "RM55_DROME", "id": "Q9VE04-1", "name": "Large ribosomal subunit protein mL55", "aln": "-----MLLKQLPQ--------AVQQIRCIS----SATTAVTRLHRSVYCRLYPTVVVQPDGSTINIRYHEPRKIIKLPLDLSTLTDAERRARLEAR--KPRKKVKIMEEVEDNFNAKKYMKYIKKK--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** * : : ::: . .: :::**::*..*.****.::*: *****:***:***::: :*:**.:*: *****:. * : :.: : *: *.:..::* :: .:. ", "identical_positions": 36, "similar_positions": 49, "identity": "28.12%" }, { "cls_id": "homologset.agr.RGD:1308162", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q3TWN3-1", "uniprot_id": "CNNM2_MOUSE", "id": "Q3TWN3-1", "name": "Metal transporter CNNM2", "aln": "-MIGCGACEPEVKMAGGQAAAALPTWKMAARRSLSARGRGVLQAAAGRLLPLLLLSCCWGAGGCTAAGENEETVIIGLRLEDTNDVSFMEGGALRVSERTRVKLRVYGQNINNETWSRIAFTEHERRRHT-PSERGLGGPAPPEPDSGPQRCGIRTSDIIILPHIILNRRTSGIIEIEIKPLRKMEKSKSYYLCTSLSTPALGAGGSGSASGTVGGKGGAGVAGLPPPPWAETTWIYHDGEDTKMIVGEEKKFLLPFWLQVIFISLLLCLSGMFSGLNLGLMALDPMELRIVQNCGTEKEKNYAKRIEPVRRQG-NYLLCSLLLGNVLVNTTLTILLDDIAGSGLVAVVVSTIGIVIFGEIVPQAICSRHGLAVGANTIFLTKFFMMMTFPASYPVSKLLDCVLGQEIGTVYNREKLLEMLRVTDPY--NDLVKEELNIIQGALELRTKTVEDVMTPLRDCFMITGEAILDFNTMSEIMESGYTRIPVFE-GERSNIVDLLFVKDLAFVDPDDCTPLKTITKFYNHPLHFVFNDTKLDAMLEEFKKGKS-HLAIVQRVNNEGEGDPFYEVLGIVTLEDVIEEIIKSEILDETDLYTDNRTKKKVAHRERKQDFSAFKQTDSEMKVKISPQLLLAMHRFLATEVEAFSPSQMSEKILLRLLKHPNVIQELKYDEKNKKAPECYLYQRNKPVDYFVLILQGKVEVEAGKEGMKFEASAFSYYGVMALT-----ASPVPLS----------LSRTFVVSRTEVLAAGSPGENKSPPRPCGLNHSDSLSRSDRIDAMT-PTLGSSNNQLSSSFLQVYIP-----DYSVRALSDLQFVKISRQQYQN----------ALMASRMDKTPQSSDSENTKIELTLTELHDGLPDETANLLNE-QNCVSHNKANHSLHSEGAI-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5U2P1-1", "uniprot_id": "CNNM2_RAT", "id": "Q5U2P1-1", "name": "Metal transporter CNNM2", "aln": "-MIGCGACEPEVKMAGGQAAAALPTWKMAARRSLSARGRGVLQAAAGRLLPLLLLSCCCSAGGCTAAGENEETVIIGLRLEDTNDVSFMEGGALRVSERTRVKLRVYGQNINNETWSRIAFTEHERRRHT-PGERGLGGPAPPEPDSGPQRCGIRTSDIIILPHIILNRRTSGIIEIEIKPLRKMEKSKSYYLCTSLSTPALGAGGSGSASGTVGGKGGAGVAGLPPPPWAETTWIYHDGEDTKMIVGEEKKFLLPFWLQVIFISLLLCLSGMFSGLNLGLMALDPMELRIVQNCGTEKEKNYAKRIEPVRRQG-NYLLCSLLLGNVLVNTTLTILLDDIAGSGLVAVVVSTIGIVIFGEIVPQAICSRHGLAVGANTIFLTKFFMMMTFPASYPVSKLLDCVLGQEIGTVYNREKLLEMLRVTDPY--NDLVKEELNIIQGALELRTKTVEDVMTPLRDCFMITGEAILDFNTMSEIMESGYTRIPVFE-GERSNIVDLLFVKDLAFVDPDDCTPLKTITKFYNHPLHFVFNDTKLDAMLEEFKKGKS-HLAIVQRVNNEGEGDPFYEVLGIVTLEDVIEEIIKSEILDETDLYTDNRTKKKVAHRERKQDFSAFKQTDSETKVKISPQLLLAMHRFLATEVEAFSPSQMSEKILLRLLKHPNVIQELKYDEKNKKAPECYLYQRNKPVDYFVLILQGKVEVEAGKEGMKFEASAFSYYGVMALT-----ASPVPLS----------LSRTFVVSRTEVLAAGSPGENKSPPRPCGLNHSDSLSRSDRIDAMT-PTLGSSNNQLSSSFLQVYIP-----DYSVRALSDLQFVKISRQQYQN----------ALMASRMDKTPQSSDSENTKIELTLTEMHDGLPDETANLLNE-QNCVSHNKANHSLHSEGAI-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H8M5-1", "uniprot_id": "CNNM2_HUMAN", "id": "Q9H8M5-1", "name": "Metal transporter CNNM2", "aln": "-MIGCGACEPKVKMAGGQAAAALPTWKMAARRSLSARGRGILQAAAGRLLPLLLLSCCCGAGGCAAVGENEETVIIGLRLEDTNDVSFMEGGALRVSERTRVKLRVYGQNINNETWSRIAFTEHERRRHS-PGERGLGGPAPPEPDSGPQRCGIRTSDIIILPHIILNRRTSGIIEIEIKPLRKMEKSKSYYLCTSLSTPALGAGGSGSTGGAVGGKGGSGVAGLPPPPWAETTWIYHDGEDTKMIVGEEKKFLLPFWLQVIFISLLLCLSGMFSGLNLGLMALDPMELRIVQNCGTEKEKNYAKRIEPVRRQG-NYLLCSLLLGNVLVNTTLTILLDDIAGSGLVAVVVSTIGIVIFGEIVPQAICSRHGLAVGANTIFLTKFFMMMTFPASYPVSKLLDCVLGQEIGTVYNREKLLEMLRVTDPY--NDLVKEELNIIQGALELRTKTVEDVMTPLRDCFMITGEAILDFNTMSEIMESGYTRIPVFE-GERSNIVDLLFVKDLAFVDPDDCTPLKTITKFYNHPLHFVFNDTKLDAMLEEFKKGKS-HLAIVQRVNNEGEGDPFYEVLGIVTLEDVIEEIIKSEILDETDLYTDNRTKKKVAHRERKQDFSAFKQTDSEMKVKISPQLLLAMHRFLATEVEAFSPSQMSEKILLRLLKHPNVIQELKYDEKNKKAPEYYLYQRNKPVDYFVLILQGKVEVEAGKEGMKFEASAFSYYGVMALT-----ASPVPLS----------LSRTFVVSRTELLAAGSPGENKSPPRPCGLNHSDSLSRSDRIDAVT-PTLGSSNNQLNSSLLQVYIP-----DYSVRALSDLQFVKISRQQYQN----------ALMASRMDKTPQSSDSENTKIELTLTELHDGLPDETANLLNE-QNCVTHSKANHSLHNEGAI-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AJ29-1", "uniprot_id": "A0A8M3AJ29_DANRE", "id": "A0A8M3AJ29-1", "name": "Metal transporter", "aln": "-------------MA--EPSVPVPPRKMAS-----------LSRVRAFTLIFLTASSCLITPTSGKEGGGEETVIIGLRLEDTDDISFMDRGFLRVSERSRVRLRVYGQNINNETWSKIAFTEHERSRVIGNIDSSSGDNQSQEDTSGLHPCGIRTSDILILPNIVLNRKTSGTVEIEVKPLRKTERSKAYYLCIATSTPAVAG---------------------AHDPWTENTWIYHDGEDTKVIVVEEKKFLLPFWLQVIFISMLLCLSGMFSGLNLGLMALDPMELQIVQNCGTEKEKNYARKIEPVRSQG-NYLLCSLLLGNVLVNTTLTILLDDIAGSGLIAVVMSTIGIVIFGEIVPQAICSRHGLAVGANTIFLTKFFMLLTFPASYPVSKLLDYLLGQEIGTVYNREKLLEMLRVTDPY--NDLVKEELNIIQGALELRTKTVEDVMTPLRDCFMITGDATLDFNSMSEIMESGYTRIPVFE-GDRSNIVDLLFVKDLAFVDPDDCTPLKTITKFYSHPLHFVFNDTKLDAMLEEFKKGKS-HLAIVQRVNNEGEGDPFYEVLGIVTLEDVIEEIIKSEILDETDLYTDNKTKKKITHRERKQDFSAFKHMDNEMKVKISPQLLLATLRFLATEVEPFSPSQMSEKILLRLLKHPNVIQEVKYNDKNKKAIEHYLFHRNKPVDYFILILQGKVEVEAGKEGLRFEAGAFSSYGMMALT-----ASPVPLS----------LSRTFVVSRAESVAGSPGMENKSPPRSFGLNHSDSLNRSERIEVIT-PSLGSSNNQLN-AFLQIYVP-----DYSVRAVSDVQYIKVTRQQYQN----------AVMASRIDKTPQSSESEYTKIEMTLTELHDGLTDETTTLFNQTQNCVVHNKSNHTGHSEGPI-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B7P9G0-1", "uniprot_id": "UEX_DROME", "id": "A0A0B7P9G0-1", "name": "Unextended protein", "aln": "MNTYFISFITIIIFANGINGTSVDTSNKLL-----------LQKANDFNLSQNLSSSRTRRTIANSFR------IVGIRLED--ETVETKNGIPTVLVDKEQQFRVFGSGLEEN--TAITFTNEK---------NDYGGP------------CLKPATDLFTPIEVSSNGFSALYSVKFPSFIN-----EFFICAKTAEKTTNH-----------------------SKAATTTPLEHQG-NSDFLKIKTFEPLIPVWLAIIIIVTCLGFSALFSGLNLGLMSMDRTELKILRNTGTEKEKKYASKIAPVRDQG-NYLLCSILLGNVLVNSTFTILLDGLT-SGLFAVIFSTLAIVLFGEITPQAVCSRHGLAIGAKTILVTKTVMAITAPLSYPVSRILDKLLGEEIGNVYNRERLKELVRVTNDV--NDLDKNEVNIISGALELRKKTVADVMTHINDAFMLSLDALLDFETVSEIMNSGYSRIPVYD-GDRKNIVTLLYIKDLAFVDTDDNTPLKTLCEFYQNPVHFVFEDYTLDIMFNQFKEGTIGHIAFVHRVNNEGDGDPFYETVGLVTLEDVIEELIQAEIVDETDVFVDNRTKTRR-NRYKKADFSAFAERREVQTVRISPQLTLATFQYLSTAVDAFKKDVISELILRRLLNQ-DVFHNIKTKGKSKDDPSLYIFTQGKAVDFFVLILEGRVEVTIGKEALMFESGPFTYFGTQALVPNVVIDSPTQMGSLQSLNMDSKIRQSFVPDYSVRAISDVIYITIKRVLYLTAKKATLLEKSRKSGTFSSETFDDEVERLLHSITENEKPSCFAQNQSTRRLSNRSINSSPTNMNRSPDFVYNSVDEAIQDDTKLKNIKHADNVTTSISLVAAELEDLHSGEQDTTAASMPLLPKLDDKFESKQSKP---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12296-1", "uniprot_id": "MAM3_YEAST", "id": "Q12296-1", "name": "Protein MAM3", "aln": "-------------------------------------------------MSFLPLRSRSRSGAP---------HWVYIILYHIFTIPKIYS-LPLLSGSHVLNSR-------------------------------------------------------------------------------------------------------------------------------------DVADSGHSVGDEASVTTYYIISIILVLLG----GVFAGLTLGLMGQDEVYLKVISTSGSNSEKKLAKRVLDLISRGKHWVLVTLLLSNVITNETLPIVLDRCLGGGWQAVVSSTILIVIFGEIIPQSVCVKYGLQVGAFFCPFVLVLMYLMYPVAYPIATLLDYMLGEDHGTMYKKSGLKTLVTLHRTMGVERLTKDEVTIISAVLDLKAKRVEEIMTPIENVFTMSADTILDDKTVEKIFNSGFSRIPIFLPNEPNNFIGMLLVRVLISYDPDDCLPIS---HFPLATLPETSPNTSCLNILNYFQEGKA-HMCVVSKEPGSSHG-----AIGVLTLEDVIEELIGEEIVDESDVFVDMHQHIMRQQPGPLSKRHITSYLHHLYTSSHKEHKAADQADESSPLLSPSNSNHPSEHPQQDLNNKSWKQKSNDGYDRSNAVLSPTPQVTEHGTIIPSNLASNPLNVNKSFVTIKKPANVPKIITTHTPHSSKE-PSPAPHSNDKS---LSAEEQQLLSDHAELSRQAVLHTQRSGQPTQVTTSTKTTRNSPDSISIPNSGANHGNENQNVTISTSYQNTKNGIVESVITVKGVPKTIIGPAKDWDESKSEYGNENINQENSNRSDDRESSSSNASLFSSIKNKFKNENANNNDRSNFTDSLSRTSNYDANGSSSTIKR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : : * . : . * : :: . . : :*:: .:*:**.****. * *::: . *::.**: * :: : :* :::* ::**.**:.* *:.*:** .* **: **: **:**** **::* ::** :** .. .* : * :**:: :** :**:: *.:*::. * :: : : * *:*:.**...*:*: * * ::** :.: * :: :: ** :::.:*::**::***:: .: .*:: :* :: * *.** *:. .* .: . : . ::: *::*. *:..* : ....* .:*::********:* **:**:*::.* : : : . . . : :. :.. . . ** * :: :. . :.: . : . : .. ::* . : :. . : **. . : :: . : . . : .* .. . :. :: *. :.. . . . : :.. :.: : . : .. . .. ", "identical_positions": 113, "similar_positions": 218, "identity": "12.35%" }, { "cls_id": "homologset.agr.RGD:1308163", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q3ZU82-1", "uniprot_id": "GOGA5_RAT", "id": "Q3ZU82-1", "name": "Golgin subfamily A member 5", "aln": "-MSWFADLAGRAEDLLNRVDQGAATALRKESTSNTFYSKNTDYPELHQQNTDSTYHTGQK-----------ANYISSAADNIRHQKATIIAGTANVKVGSRTGGDASHPTEHASVPRPSSHFVRRKKSEPDDELLFDFLNSSQKEPTGRVEIKKE--------KGKAPVLPSSQSSAVSSVTTSVTTIKATEENS-GSQSPEVSS-SDSMPEGHKKSTEESTVSNAISVEHSSVPSDGS----------------------MSHELSNLRLENQLLRNEVQSLNQEMASLLQRSKETQEELNEARVRVEKWNVDNSKSDRITRELRAQVDDLTEAVAAKDSQLAVLKVRLQEADQVLSSRTEALEALQSEKSRIMQDHNEGSSLQNQALQTLQER-HEADATLKREQESYKQMQSEFATRLNKMEVERQNLAEAVTLAERKYSEERKKVDDLQQQVKLHRSSLESAKQELVDYKQKATRILQSKEKLINSLKEGSSFEGLDS-STASSMELEELRHERELQKEEIQKLMGQIHQLRSELQDMEAQQVS---EAESAREQLQDLQDQIAKQRASKQELETELDRMKQEFHYVEEDLHRTKNTLQSRIKDREEEIQKLRNQLTNKTLSNSSQSELESRLHQLTETLIQKQTLLESLSTEKNSLVFQLERLEQQLHSAATGPSSGSSINMSGVDSGEGTRLRNVPVLFNDTETNLAG-MYGKVRKAASSIDQFSIRLGIFLRRYPIARVFVIIYMALLHLWVMIVLLTYSPEMHHDQPYGK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QYE6-1", "uniprot_id": "GOGA5_MOUSE", "id": "Q9QYE6-1", "name": "Golgin subfamily A member 5", "aln": "-MSWFADLAGRAEDLLNRVDQGAATALRKENTSNIFYSKNTDYPELQQQNTDSNYQTGQK-----------ANYISSAADNIRHQKATILAGTANVKVGSRTVGDATHPTEHASAPRPSSQFVRRKKSEPDDELLFDFLNSSQKEPTGRVEVKKE--------KGRAPVSPSS-PSGVSSVNTSVTTTKAMGGNA-GSQSPGVNS-SDSVPEVHKEPSEESTAPSATSEEHSSTPSDGSS---------------------RSQELSNLRLENQLLRNEVQSLNQEMASLLQRSKETQEELNKARVRVEKWNVDNSKSDRITRELRAQVDDLTEAVAAKDSQLAVLKVRLQEADQVLSSRTEALEALRSEKSRIMQDHKEGSSLQNQALQTLQERLHEADATLKREQESYKQMQSEFAARLNKMEVDRQNLAEAVTLAERKYSEEKKKVDELQQQVKLHRASLESAKQELVDYKQKATRILQSKEKLINSLKEGSSFEGLES-STASSMELEELRHEKEMQKEEIQKLMGQMHQLRSELQDMEAQQVS---EAESAREQLQDLQDQIAKQRTSKQELETELERMKQEFRYMEEDLHRTKNTLQSRIKDREEEIQKLRNQLTNKTLSNSSQSELESRLHQLTETLIQKQTMLESLSTEKNSLVFQLERLEQQVHSASSGPNSGSAINMSGVDSGEGTRLRNVPVLFNDTETNLAG-MYGKVRKAASSIDQFSIRLGIFLRRYPIARVFVIIYMALLHLWVMIVLLTYSPEMHHDQPYGK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TBA6-1", "uniprot_id": "GOGA5_HUMAN", "id": "Q8TBA6-1", "name": "Golgin subfamily A member 5", "aln": "-MSWFVDLAGKAEDLLNRVDQGAATALSRKDNASNIYSKNTDYTELHQQNTDLIYQTGPK-----------STYISSAADNIRNQKATILAGTANVKVGSRTPVEASHPVENASVPRPSSHFVRRKKSEPDDELLFDFLNSSQKEPTGRVEIRKE--------KGKTPVFQSSQTSSVSSVNPSVTTIKTIEENSFGSQTHEAASNSDSSHEGQEESSKENVSSNAACPDHTPTPNDDG----------------------KSHELSNLRLENQLLRNEVQSLNQEMASLLQRSKETQEELNKARARVEKWNADHSKSDRMTRGLRAQVDDLTEAVAAKDSQLAVLKVRLQEADQLLSTRTEALEALQSEKSRIMQDQSEGNSLQNQALQTFQERLHEADATLKREQESYKQMQSEFAARLNKVEMERQNLAEAITLAERKYSDEKKRVDELQQQVKLYKLNLESSKQELIDYKQKATRILQSKEKLINSLKEGSGFEGLDS-STASSMELEELRHEKEMQREEIQKLMGQIHQLRSELQDMEAQQVN---EAESAREQLQDLHDQIAGQKASKQELETELERLKQEFHYIEEDLYRTKNTLQSRIKDRDEEIQKLRNQLTNKTLSNSSQSELENRLHQLTETLIQKQTMLESLSTEKNSLVFQLERLEQQMNSASGSSSNGSSINMSGIDNGEGTRLRNVPVLFNDTETNLAG-MYGKVRKAASSIDQFSIRLGIFLRRYPIARVFVIIYMALLHLWVMIVLLTYTPEMHHDQPYGK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7SXE4-1", "uniprot_id": "GOGA5_DANRE", "id": "Q7SXE4-1", "name": "Golgin subfamily A member 5", "aln": "-MSWFVDLAGKAEDFLNKVDQGAATALTKPNQKSSLSYNSPDATDSTQYNAAAYSSTQQHRDSISASSLGTSTFISAAAGNIKKSKATVLAGTANVSS----------TTPLGSSSKASSNFVRPRKSEVNDDLLFDFLNSSDPPQSEKKEVRRETVSKAFSPTGVSAQSQMPTVSLASDLHTGPSVTPTPSSTQGLSRNSSLGSLSSSSHSVKTEDSSTRDQSQADVPESLTAGLDDLADPQPVLEIQSQDLQQQQQQQGQEHVISNLRLENQLLRNEVSSLNQEMASLIQRAKDMQEEVNLGRARADKWNSDQSRVDRTVRELSSQVDDLTEALSAKDGQLAVLKVRLDEADQLLKARSSALEEAQNERVRILQDHSEGSSLHSQAVQTLQDRLRDAEAAVKREQESYRQIQSEFAARLAKVEAERQTLAESLTNAERRLTEEKQRAEDLQQQAKSSRSAAEYTKQELQDYKNKASRILQSKEKLINSLKEGSGLEVLEG-AGAG-VELEELRHEKELQREEIQKLQAQIQSLRTEIQDLETQALT---ENESWREQLAEVQEQHAQQIRAKQEIEAELERSKQELQYIEEEHHRTKITLQGRVKDREDEIQKLRNQLTNKALSNSSQAELEGRLHQLTETLIQKQTMLEALGTEKNSLVFQLERLEQQLKSLQGGQNSASHINMAAME-GPGARQRNTPILFSDGDGPGTG-VYGKVRKAASTIDRFSIRLGIFLRRYPMARVFVIIYMALLHLWVMIVLLTYTPEMHHSHPDGR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8SZ63-1", "uniprot_id": "GOGA5_DROME", "id": "Q8SZ63-1", "name": "Golgin-84", "aln": "MSSWITGLADKAENILNKLDQNAATALQTENAT-----------------------------------------------------------------------------------------------------------------------------------GSADPMRRSMTSSTQSLSTSLKSTLSPVRRSGANSSSSVKSDGGVSVVTKDMRQKMTTSASFSNSPDISANSMDTN---------------------------------------------ELAAFKIALNEITAERDELRLRLEDLNNETEKFD------------------------------LHQHTQVLEALVKSLSEERD---KAVHDYNEAQAAN----------------------MAYVHSISELETNLAKLQQEYISAAHKLQMQTKETEQQR---------------------QELQEYRIKAQRALQAKDSLIAELKAKPTEEGADPNLVSKDSETRFLQIEHESLKQELEHANEELQKARLQLDDYVSQERQRQVELSSARQREETLAKELRQAREHSVTSESDQRVLTQELASLRQQLSNQMAAAATRLQEREQQLQQMRQRLSEEANTG-AKSDYETRLKALTQSLVERQSLLERVTSERNALRLQHEKAQTQLQQNMHLVEMESQRGSSRHTMLNSTDDVKAQFPLLMHPSPFDNRVARRFKRALRQADSMGIRVGTFLRRYPMMRVSVIVYVALLHLWVMFVLLSTTPN---------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **:..**.:**::**::**.***** . * : . * ...: .. . : . . * .. : . .. .. . *:*:: :: * : * * :. * : .: * *.: *:*.: .:*. :. : ::* .*..: : :* : **: :.* *:: : . *. : :. ::: *** :*: ** * **:*:.** .** . * : : * . *: *:* ::*::: :::. * :::* :* * .* *:: : .: . *:: .**: :.:: . : *:::*::::*::*::*:::: :. :::: * **: **::*:::*::** : :*:*:* :* *: : *::. . * . : .: :. . : . : :.::* * :.**:* ******: ** **:*:********:***: :*: ", "identical_positions": 115, "similar_positions": 183, "identity": "14.78%" }, { "cls_id": "homologset.agr.RGD:1308164", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8NHX4-1", "uniprot_id": "SPTA3_HUMAN", "id": "Q8NHX4-1", "name": "Spermatogenesis-associated protein 3", "aln": "MKKVK-------KKRSEARRHRDSTSQHAS--------------SNSTSQQPSPESTPQQP---------------SPESTPQQPSP---ESTPQHSSLETT------------------------------------------------------------SRQP-------AFQALPA---------------------PEIRRSSCCLLSPDAN-----VKAAPQS---------RKAG-PLIRAGPHSCSCATCPCSSACWRRLGLCHSRIFDVLLPRDWQMAPGRGLPNLLTFYRKSSRKPSSHRNACPPSPRNCGCGSGGSRSCLLHH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9D9T6-1", "uniprot_id": "SPTA3_MOUSE", "id": "Q9D9T6-1", "name": "Spermatogenesis-associated protein 3", "aln": "MKKVK-------KKKSDSRRRRNSISPQTS--------------SDS-SQQPSSETPPSCP---------------EPASPPSKPQPCQESTTPHQVNPEPK------------------------------------------------------------PQQH-------TPQPLPP---------------------PEKPASSPFLVPMEP-------KPILPS---------RKAAVPLTYVAPRSCSCAACPGSSACWHRLGLCHSRIFDVLLPRDWSSMPGRGVPNLLTFYRKPSRKYCAPRNSRASSSRNCCCGSGGLGSCLLHG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AFR5-1", "uniprot_id": "A0A8I6AFR5_RAT", "id": "A0A8I6AFR5-1", "name": "", "aln": "MKQRPGEQPSRAPKEEKMEEQPETPSQSISGRGRVLLVREFFKPEESYTNQPVYTHTTDCQSCGGSVRPGLKRTGDSLADNPEAPAAKRRAEKSQLSGHQKKDLLDCEAPRASQGNLGSEVAEITKLSTEPGKQLLLVLCHASALYTQLPRLQLLLQQVRVQDRRPPAALVGILVQPRPDEEAESRRRLEDLLYSIFSSDNPEVEVHTAVFCPSRPQGVLDVQRAASPAHMVPLMDRQTQTDVPLTYAAPRSCSCVVCPGSSACWRRLGLCHSRIFDVLLPRDWSSMPGRGFPNLLTFYRKPSRKYCTSRNSRASSPRNCCCGSGGPGSCLLHG", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: *... ..: :: * * .:* ::** ... . . *. * . ..: . : . :: *. * ** : : . . :. : :: ** ..*:****..** *****:******************. ****.*********.*** .: **: ..*.*** ***** ***** ", "identical_positions": 78, "similar_positions": 53, "identity": "23.35%" }, { "cls_id": "homologset.agr.RGD:1308165", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4A3I3-1", "uniprot_id": "D4A3I3_RAT", "id": "D4A3I3-1", "name": "Myb/SANT-like DNA-binding domain-containing protein 3", "aln": "MQNNEIIKPAKYFSELEKSILLALVEKYKYVLECKKSDARTIALKQRTWQALAHEYNSQPSVSLRDFKQLKKCWENIKARTKKIMAHERREKVKRSGSPLLSTHVLDKEKIGSMLPEQLYFLQS-------------------------PPEEEPEYHQ----------------------------DAAAQESFAVSNRELCDDEKEFVHFP--------------------------------------------VCEG----------TSQPEP---------------------------------------------------------------------SCSAVRITANKNYRSKTP--------------------QEGALKKMHEEE--------------------HHQQMSILQLQLIQMNEVHV------------------------------------------------------------AKIQQIERECEMAEEEHRIKMEVLNKKKMYWE---RKLQTFTKEWPVSSFNRPFPNSP-----------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CR78-1", "uniprot_id": "MSD3_MOUSE", "id": "Q9CR78-1", "name": "Myb/SANT-like DNA-binding domain-containing protein 3", "aln": "MQNNEIIKPAKYFSELEKSILLALVEKYKYVLECKKSDARTIALKQRTWQALAHEYNSQPSVSLRDFKQLKKCWENIKARTKKIMAHERREKVKRSGSPLLSSHVLDKEKISSMLPEQLYFLQS-------------------------PPEEEPEYHQ----------------------------DAAAQESFAVSNRELCEDEKEFGPFP--------------------------------------------VCEG----------TSQPEP---------------------------------------------------------------------SCSAVRITANKNYRSKTP--------------------QEGALKKMHEEE--------------------HHQQMSILQLQLIQMNEVHV------------------------------------------------------------AKIQQIERECEMAEEEHRIKMEVLNKKKMYWE---RKLQTFTKEWPVSSFNRPFPNSP-----------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96H12-1", "uniprot_id": "MSD3_HUMAN", "id": "Q96H12-1", "name": "Myb/SANT-like DNA-binding domain-containing protein 3", "aln": "MQNNEIIKPAKYFSELEKSILLALVEKYKYVLECKKSDARTIALKQRTWQALAHEYNSQPSVSLRDFKQLKKCWENIKARTKKIMAHERREKVKRSVSPLLSTHVLGKEKIASMLPEQLYFLQS-------------------------PPEEEPEYHP----------------------------DASAQESFAVSNRELCDDEKEFIHFP--------------------------------------------VCEG----------TSQPEP---------------------------------------------------------------------SCSAVRITANKNYRSKTS--------------------QEGALKKMHEEE--------------------HHQQMSILQLQLIQMNEVHV------------------------------------------------------------AKIQQIERECEMAEEEHRIKMEVLNKKKMYWE---RKLQTFTKEWPVSSFNRPFPNSP-----------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A6H2EFE9-1", "uniprot_id": "A0A6H2EFE9_DROME", "id": "A0A6H2EFE9-1", "name": "Regulatory protein zeste", "aln": "------MEKTPRYTQRERNMVLSYAAQYKDVIENKRTDAESNRKKDEVWLQIAKEFNSR-VYHQRSAKQLRQLYKNMKLLLKKDLCGE--DKSNHSFMDLLN-TLSHQESVAQYIAEQLSPEGAGGGGGGGKQGGAGNGGGNGHQSDDYDDSKMPHYHEGMDTDVILIKSETISDNEQTDNGMDCLDEDDDDDCLSHKAPEVCLEEEDDVLFPTDVRQLQQVGSSGAAGGGVSGGSLPGNMSSNGITETSRRAASSPVCSTKTSISSSGSYASAPKPDITIQTVGHIRVGSFANINKTLQNGGSGTGAVLSAASNGGSSASGVLPLTAEQVQQHTLLNGLGLSAVNPAQSLQAAINAAYGSAAPSSSVAISSRRTPPTLQLPRLQRGNINNSHHTAGSTSNSAVASNGVQLLLNGGHHAQMTHNHLARDKTGGVAIGAAGSFNGYNGLAVAGTVCSALNSSGSGAGSGGSSANNSGVGLGIGGAHTSGSGGSGSGGTRSQHQELMNSLRIEESKRKIDLINAQIEYWQTLTRKLNSQANHMPNPACPCHFPGASVLSPVAVTAASASSSASANVLQTQASTSXSAAKGRFELVGGPAGESESDSDIISIVDIDDGRSREDEQSEDDGENRDQAITDLTLPDEDEEDDVDEDDSQDALVRDVGVVGGLSSPDTPPHSSPPPAKRSKRQEVTSELLRQLALQQNQDPQEGC", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : ::: *:.::*: . :** *:* *::**.: *:..* :*:*:**: *. ***:: ::*:* ** :. * :* ::* **. : :*.:.. :.*** : .: *.** : ::.:: . *:* :*:: ** **. :* *:* ...::: : * * * :. *.* ::: *. ** **: :* : . * : :: *: * .: ** : *::::* : **: ***:: ::. * .: **.:. ", "identical_positions": 71, "similar_positions": 104, "identity": "10.01%" }, { "cls_id": "homologset.agr.RGD:1308168", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AKP6-1", "uniprot_id": "A0A8I6AKP6_RAT", "id": "A0A8I6AKP6-1", "name": "E3 ubiquitin-protein ligase RNF213", "aln": "-MGCPQCGHVSSEKAAKFCSQCGQKLSPAATEQ-DLKNNNALVEASTTEGKTEPGEVLREEVVLLSSTDSGKELQTEQGEVLREEVVLLSSTDSGKELQNPEESESDASWTTHVSKKEKRRRRRQGTISSS----EAASMSSGLWSLDLP----------SGPGSHNSALPQNQAQQGGTANQPGHSLDTVKMPVEKDGSACVEGSG-SSLRGPVAEGP-----EDAQRNPAASDYVEVKDLKTSNPSVDKG----------------PKMTDASQKASLPESKGEQP---------------GHGEKVPPIDTAANPVKRAR--KETRDDVQKQKPSPVSLATSK-DRDQKAELESKLATPVRKSDESRNTQ--PEDQKKPGGDRNYAAAAKNKNQ---QAAALEATKS-------THDPGDRVTVCFHAIVSRDFGFNPDKHRAYVRGGEGLGQKGWT-DACEMYYTQDLHDLGSLIEGKMDIPRQSLDKP-IPYKYVIHHGSSSKDSVEYEFIYEQPQKKGEHVNRCLQVDSTLLSS-GDWHQYDDIIWMRSPG-LLQQAKNYITDGTRKNLVRGKKQAAVIMLDRIFSVLQSWSAINLQTFMTQFRQFYSVVRVPMIHDGHARKWSSLQYEEREVRLNLWEHVKKLMMPFLEGKSGESLPADCPVRSKQILGLSILCMVEAADFTVPKKDLDSLCYLLIPSADSPE---ALHRDLSPVLSIRQRWHAYLITLCFRCIEVGCDRWLGILPLLHYCMQQSPPRKNSKSQT----EDVWAGLEGISFSEFRDKAS----ARSQALQLMQNRMALLHVDEYLFRSWFSLVPLESLSSYLENSEEYLSHMPTRVLDCFQGISYRLRGLGKISKQNIE----DVKKVFKILMYLVDMYQDRIFEESLPQIYLTECADLHETVCSITADRQFYQTPALSAELVCAVLQLSPPEHTEEGLVAKSYEDLVRTTFQEALNTTRKWLRTVFKSPMLSRNFAAVQLS---YPDEMAVWRRLVGINFPEK---YGWKGPLLGDMEGRLKQESPRLQISFFCSSHCCDEGP--HDSVARSIEKCVIEAVSSVCQSQTSVLEGLSCQDLQK---FGTLLSAVITKSWP-VHNGELVSDVDEIFKYLLKWPDVRQLFKLCGTNENITNHITKEGRRLMVTAESVFQKVAGELENGTIVVGQLELILKYKSQFLGIWDINSQRLQFQ-EKVYDMKGLLDRRKDDLFFLKREKRYVESLLTQLGRVKHFVQVELG----NIERIHSQDLSNKKLN---EAVIK-PPNSSFSNRKTHYYLSPDILEMASKLDSLKDSHVFQDFWHETAELLSNDTLDQDRRELK-----------LSLPDVVDHLYYPCYEKFYKLYMNLRSGEITFADVDVIFR--DFKDKYDELNVDLKFMCTLDPQDRKGWISQRVRQIKEYHTLYQAVSSAKVIVQVRRALGVTGDFSVLNPLLNFADDFEDFRNEKLNQISPQFIKAKELLQDISELRHRCLEELALQTELVHWLHEALKDINELKVFVDLASISAGENDIDVDRVACFHDAVQGYASLLYKLGANTDFNEFMNHLQELWRALDNDQHLPDKLKDSARNLEWLKTVKESHGSVELSSLSLATAINSRGIYIIQAPKDG-QKVSPDTVLHLLLPDDHGYQEAFRKYSTEELKELLNKLMLMSGRKDHSSNVEVETFSEVFSNMQRLVHVFINLHCAGNMLFRTWTAKVYCCP--GGGISMDFGS-KLLNQLTESGDVIQLLGALCRQMEDFLHEWKTVVAQKRATHFYLNLYTAEQLVYLSSELRK-----PRPSEAALMMLSFIKGKCTVQELIQATSACENKAAR-------------HCLQEAMRKLP------------QQLLSESTLMGKLRVIMTQSLECMSAFLPSCLDLDTLGRCLAHLARLGGS------------PVERPLPKGLQVGQPNLILCGHSEVLSAALAIYMQDPMQPLPTFDEVLLCTPGTTIEEVELFLRRCLT-LDSQEHKVYSLLFADQLSYEVGCQAEELFQSLSTQVHREDYQLVILCDAAREHCYIPSTFSQHKVPLVPQAPLPDIQAYLENHYQVPKQIQSAATVFRDGLCVGIVTSERAGVGKSLYVNTLHKKLKTKLQDETVPLKIIRLTEPHIDENHVLSALLPFLEKNYQKTPVIFHIDVSTSVQTGIPVFLFKLLILQYLMDINGKMWRRNPCHLYVVEIPQAHSVRPKRSS-KLNARAPLFKFLDIFPKVTCRPPKEVINMELTPKRS-----HIEPGMDPAEFCSEAFQRPYQYLRRFHQGQNLDAFRYEKDSVEGSPEECLQHFLIYCGLTNPSWSELRNFAWFLNCQLKDCEASVFCNSAFTGDTLRGFKNFVVTFMVLMARDFATPTLQTSDQSPGKHSATIDGVAEEDLAPFSLRKRWESEPHPYVFFNGDRMTMTFIGFHLKTNSNGYVDAINPSSGNIIKKDVMTKELFDGLKLQRVPFNINFDSLPRHEKLERLCLALGIEWPS-----DPDETYELTTDNMLKILAIEMRFRCGIPVIIMGETGCGKTRLIKFLSDLRRGSIEAETMKLVKVHGGTTPSMIYSRVKDAERTAFFNKAQHNLETILFFDEANTTDAVSCIKEVLCDRTVGGEHLNEDSGLHVIAACNPYRKHSQEMIHRLESAGLGYRVGAEETADRLGSIPLRQLVYRVHALPPSLIPLVWDFGQLNDSAERLYIQQIVQRLVDSVTVDQRETFVIANVLSASQEFMRKRENECGFVSLRDVERCVKVFQWFHDHSNMLLNKLADFLREC------CDSTPAFERDPVLWSLVMAIGVCYHASLEEKAPYRAAIARCLPKPYNSPKVILNEITHVQDLFLRDAPIRSNIARNLALKENVFMMVICIELKIPLFLVGKPGSSKSLAKIIVADAMQGQAASSDLFRCLKQVHLVSFQCSPHSTPQGIISTFKQCARFQQGKDLQQYVSVVVLDEVGLAEDSPKMPLKTLHPLLEDGCIE-DDPAPYKQVGFVGISNWALDPAKMNRGIFVSRGSPNEKELIESAEGICSSDRLVQDRIRGYFAPFAKAYETVCQKQDKEFFGLRDYYSLIKMVFAKAKASKKGLSPRDIAHAVLRNFSG-KDDIQALSIFTASLPETLYKEEVSTVELIKQNIHPDLQGSSRG-LDSADSRYLLVLTRNYVALQILQQTFFEG-----QQPEIIFGSSFPQDQEYTQICRNINRVKVCMETGKMVVLLNLQNLYESLYDALNQYYVYLGGQKYVDLGLGTHRVKCRVHTDFRLIVIEEKDVVYKQFPVPLINRLEKHYLDMNTVLQGWQKGIVQELQRWAHEFADVKADQFIAR--HKYSPADVFIGYHSHACASVVLQAVERQGCRNLTEELY---------------------------------------------------------------------------------RKVFEEAKFILLDCATPDAVVRLSGSSLGSFAANRLSQEYYYKQQHNSFVDFLLAHLRMDHHECWAVFTEITTFSRLLTSHDCDVLESELRGLAPKPIVLSLQQFDTEYSFLKDVRSCLRNPA-RRKILVIQTDFDDGIHSAQLVASAKYSAINEINKTQ-GTEDFVFVYFVTKLSRMGS------GTPYVGFHGGLWRSVHIDDLRRSTVMASDVTKLQNVTISQLFEPVDKPEP------EDDPEEEMETESSKS---GEVAEEQMEVEEEGSEEMKRACDLRGCDV---LDTTRLVRSCVQGAVGMLRDQSESCARNMRRVTILLDLLNEESTLNASFLRESKMRLHVLLNKQEENQVRSLKEWVTREAANQDALQEAGTFRHTLWKRVQDVVTPILASMISHIDRDGNLELLARPGSPAWAQDLWMFIYSDIKFLNIPLALNNTRSNSEMPFILVQSHMNLLKDACNAVPFSWRIRDYLEELWVQAQYI----TDTEGLSKKFVEIFQKTPLGLYLAQFPTAQQQELLQSYLKDFLLLTMKVSSREELMFLQMALRSCLSELQVASGTPEE----GLSLPWVHLAYQHFRTRLQNFSRILTIHPQVLSSLSQAAEKHNLAGCEMTLDAFAAMACAEILKGDILKPSPR--VWLQLVKNLSMPLELVCSEGYLQDSGSMTRAIIQEVRALWNRIFSIALFVEHVLLGTESQIPELSPLVTKYVSLLDKCLEEDSNLKTYRPFAAVMTTLCNCKDKASKKFCRFGIQPCSICQGDAQDPVCLPCDHVYCLPCIQTWLAP-GQMICPYCKTELPDKFSPTVSQ--NHRKAIEKHAQFRHMCNSFFVDLVSTMCFKDNIPPQKSVIDTLLSLLFVQKELLRDASQR-HREHTKSLSPFDDVVDKTPVIRSVVLKLLLKYSFHEVKGYIQNYLSQLEN-KAFLTEDKTELYLLFINCLEDSVYQKTSAGCRNHER-VLREEGHFLRTYSPGLRGSEPVRTASVEYLQEMARVRLCLDLAADFLSELQEGSE-LAEDKRCFLKHVEQFCTRVNNDWHRVYLVRKLSSQRGMEFVQSFSRQGHPYQWVFPREVLAQQ---KDHLSQLDRYLVHGDEYKAVRDAMAKAVLDCKTLDVGNALSTCRSPKDQQTAYLLLALYTEVTALYRSRNGSLHPDSKQLEAMNKFINESKILSAPKINRFAKSLVANTLP----LLQTRSANGSLRVTVTEMAIHVATILLCGQDKVLEPLRNLAFYPFKMVNAFLPTMPEDLLVHAKFWEGLTNVRWYTCPNGHPCSVGECGQPMEMSICPDCRVPIGGLNHKPSVGFDVIRNNEDRTQTGHVLGNPQSSGTAEASD-RGQSPVVFILTRLLTHLAMLVGAAQTPQALMNIIKPPVQDPQGFLEQHIQRDLEQLTKILGKSADETTHVVHLILSSLLKEQHQM----TLNFTEVLSTKGCRNNWEKHFG-TLLLRELKHLDKTLPAINARISQDERISSNPVTKIIYGDPATFLPHLPQKSVVHCSKIWSCRTKITVEYLQHIVEQKNGKETVPLLWHFLQKEAELRLVKFLPEILALQRDLVKQFQNVSEVEFSSIRSFIHSHHSDGLQKLLHDRITVFLSTWNALRRSLETNGEIKLPKDYCRSDLDLDAKFEVILPRRRGLGLCGTALVSYLISLHNKMVYVVQKLSNE-DNSYSVDTSEVADLHVISYDVERDLNPLILSNCQYQVQQGGETSQEFDLEKIQRQISSRFLQGKPRLTLKGIPTLVYRRDWNYEHLFMDIKNKMTQNPLPNSAINAISGQLQSYSDACEALSIVEVTLGFLSTAGGDPSMELNVYIQEVLQMCDQTS-QVLKALNRCQLRHIIALWQFLSAHKSERRLRLKKELFQEVDVKYKEDLSPRHARLLSTFLNEAGLDSFLLELHEMIVLKLRGA--QAESSFNPSWSLKDTLVSYMETKDSDVLTEVESQFPDEILMSSCVSVWKTAATRKWDRQSR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q555-1", "uniprot_id": "RN213_MOUSE", "id": "E9Q555-1", "name": "E3 ubiquitin-protein ligase RNF213", "aln": "-MECPQCGHVSSEKAPKFCSECGQKLPSAATVQGDLKNDNTLVVSSTPEGKT------------------------EQGAVLREEEVLLSSTDPGKELEKPEESDSNASWTTQMSKKEKRRRKRQGTISSS----EAP--SSGLWSLDMP----------PSPGSHNSALPQNQAQQGGAASQPGHPLDTENMPME-DGFVHTEGSG-SPLQGQAAER------TDAQSNLAPSDLAEVKDLNTSKPSVDKGLPLDGG-PALSAFKGHPKMTDASQKAPLPESKGETS---------------GQEKKVPPIDAAASPVKTAG--KETGEDVRKPKPSPVSPVASK-HGDQEAELKGKLATPVRKSNEGGNTQ--PEDQRKPGEGRNFAAAVKTQQAAAPQQAAAPEPTS-------AFNPRDTVTVYFHAIVSRHFGFNPEEHKVYVRGGEGLGQKGWT-DACEMYCTQDLHDLGSLVEGKMDIPRQSLDKP-IPYKYVIHRGGSSKDTVEYEFIYEQAQKKGEHVNRCLRVVSTSLGN-GDWHQYDDIICMRSTG-FFQQAKNRILDSTRKELLKGKKQAAVVMLDRIFSVLQPWSDINLQSFMTQFLQFYSVVREPMIHDGRARKWTSLQYEEKEVWTNLWEHVKKQMAPFLEGKSGESLPADCPVRSKLTLGLSILFMVEAAEFTVPKKDLDSLCYLLIPSAGSPE---ALHSDLSPVLRIRQRWRIYLTNLCLRCIDERCDRWLGILPLLHTCMQKSPPKKNSKSQP----EDTWAGLEGISFSEFRDKAP----TRSQPLQFMQSKMALLRVDEYLFRSWLSVVPLESLSSYLENSIDYLSDVPVRVLDCLQGISYRLPGLRKISNQNMKK---DVENVFKMLMHLVDIYQHRIFGENLLQIYLTECLTLHETVCNITANHQFFEIPALSAELICKLLELSPPGHTDEGLPEKSYEDLVTSTLQEALATTRNWLRSLFKSRMLSISSAYVRLT---YSEEMAVWRRLVEIGFPEK---HGWKGSLLGDMEGRLKQEPPRLQISFFCSSQCRDGGL--HDSVSRSFEKCVIEAVSSACQSQTSVLEGLSCQDLQK---FGTLLSAVITKSWP-VHNGEPVFDVDEIFKYLLKWPDVRQLFELCGTNEKIIDNITEEGRQLMATAESVFQKVAGELENGTIVVGQLELILEHQSQFLDIWNLNRRRLPSQ-EKACDVRSLLKRRRDDLLFLKQEKRYVESLLRQLGRVKHLVQVDFG----NIEIIHSQDLSNKKLN---EAVIK-LPNSSSYKRETHYCLSPDIREMASKLDSLKDSHIFQDFWQETAESLN--TLDKDPRELK-----------VSLPEVLEYLYNPCYDNFYTLYENLKSGKITFAEVDAIFK--DFVDKYDELKNDLKFMCTMNPQDQKGWISERVGQIKEYHTLHQAVSSAKVILQVRRALGVTGDFSVLNPLLNFADSFEDFGNEKLDQISPQFIKAKQLLQDISEPRQRCLEELARQTELVAWLHKALEDINELKVFVDLASISAGENDIDVDRVACFHDAVQGYASLLYKMDERTNFSDFMNHLQELWRALDNDQHLPDKLKDSARNLEWLKTVKESHGSVELSSLSLATAINSRGVYVIEAPKDG-QKISPDTVLRLLLPDGHGYPEALRTYSTEELKELLNKLMLMSGKKDHNSNTEVEKFSEVFSNMQRLVHVFIKLHCAGNMLFRTWTAKVYCCP--DGGIFMNFGL-ELLSQLTEKGDVIQLLGALCRQMEDFLDNWKTVVAQKRAEHFYLNFYTAEQLVYLSSELRK-----PRPSEAALMMLSFIKGKCTVQDLVQATSACESKADR-------------YCLREVMKKLP------------QQLLSEPSLMGKLQVIMMQSLVYMSAFLPHCLDLDALGRCLAHLATMGGT------------PVERPLPKGLQAGQPNLILCGHSEVLPAALAIYMQAPRQPLPTFDEVLLCTPATTIEEVELLLRRCLT-SGSQGHKVYSLLFADQLSYEVGCQAEEFFQSLCTRAHREDYQLVILCDAAREHCYIPSTFSQYKVPLVPQAPLPNIQAYLQSHYQVPKRLLSAATVFRDGLCVGIVTSERAGVGKSLYVNTLHTKLKAKLRDETVPLKIIRLTEPHLDENQVLSALLPFLKEKYQKMPVIFHIDISTSVQTGIPIFLFKLLILQYLMDINGKIWRRSPGHLYLVEIPQGLSVQPKRSS-KLNARAPLFKFLDLFPKVTCRPPKEVIDMELTPERS-----HTDPAMDPVEFCSEAFQRPYQYLKRFHQQQNLDTFQYEKGSVEGSPEECLQHFLIYCGLINPSWSELRNFAWFLNCQLKDCEASIFCKSAFTGDTLRGFKNFVVTFMILMARDFATPTLHTSDQSPGRQSVTIGEVVEEDLAPFSLRKRWESEPHPYVFFNGDHMTMTFIGFHLETNNNGYVDAINPSNGKVIKKDVMTKELFDGLRLQRVPFNIDFDNLPRYEKLERLCLALGIEWPI-----DPDETYELTTDNMLKILAIEMRFRCGIPVIIMGETGCGKTRLIKFLSDLKRGSVEAETMKLVKVHGGTTPSMIYSKVKEAERTAFSNKAQHKLDTILFFDEANTTEAVSCIKEILCDRTVDGEHLHEDSGLHIIAACNPYRKHSQEMILRLESAGLGYRVSAEETADRLGSIPLRQLVYRVHALPPSLIPLVWDFGQLNDSAEKLYIQQIVQRLVDSVSVNPSETCVIADVLSASQMFMRKRENECGFVSLRDVERCVKVFRWFHDHSDMLLKELDKFLHES------SDSTHTFERDPVLWSLVMAIGVCYHASLEEKASYRTAIARCFPKPYNSSRAILDEVTHVQDLFLRGAPIRTNIARNLALKENVFMMVICIELKIPLFLVGKPGSSKSLAKIIVADAMQGQAAFSELFRCLKQVHLVSFQCSPHSTPQGIISTFKQCARFQQGKDLGQYVSVVVLDEVGLAEDSPKMPLKTLHPLLEDGCIE-DDPAPYKKVGFVGISNWALDPAKMNRGIFVSRGSPNEKELIESAEGICSSDRLVQDKIRGYFAPFAKAYETVCQKQDKEFFGLRDYYSLIKMVFAKAKASKRGLSPQDITHAVLRNFSG-KDNIQALSIFTASLPEARYKEEVSTVELIKQNIYPGPQASSRG-LDGAESRYLLVLTRNYVALQILQQTFFEG-----QQPEIIFGSSFPQDQEYTQICRNINRVKICMETGKMVVLLNLQNLYESLYDALNQYYVYLGGQKYVDLGLGTHRVKCRVHTAFRLIVIEEKDVVYKQFPVPLINRLEKHYLDMNTVLQPWQKSIVQELQQWAHEFADVKADQFIAR--HKYSPADVFIGYHSDACASVVLQAVERQGCRDLTEELY---------------------------------------------------------------------------------RKVSEEARSILLDCATPDAVVRLSGSSLGSFTAKQLSQEYYYAQQHNSFVDFLQAHLRMTHHECRAVFTEITTFSRLLTGNDCDVLASELRGLASKPVVLSLQQYDTEYSFLKDVRSWLTNPG-KRKVLVIQADFDDGTRSAQLVASAKYTAINEINKTQ-GTKDFVFVYFVTKLSRMGS------GTSYVGFHGGLWRSVHIDDLRRSTIMASDVTKLQNVTISQLFKPEDKPE-----------QEEMEIETSQS---KELAEEQMEVED--SEEMKKASDPRSCDCSQFLDTTRLVQSCVQGAVGMLRDQNESCARNMRRVTILLDLLNEDNTRNASFLRESKMRLHVLLNKQEENQVRSLKEWVTREAANQDALQEAGTFRHTLWKRVQDVVTPILASMIAHIDRDGNLELLAQPDSPAWVQDLWMFIYSDIKFLNISLVLNNTRSNSEMSFILVQSHMNLLKDAYNAVPFSWRIRDYLEELWVQAQYI----TDTEGLSKKFVEIFQKTPLGVFLAQFPVAQQQKLLQSYLKDFLLLTMKVSSREELMFLQMALWSCLRELQEASGTPDETYKFPLSLPWVHLAFQHFRTRLQNFSRILTIHPQVLSSLSQAAEKHSLAGCEMTLDAFAAMACAEMLKGDLLKPSPK--AWLQLVKNLSTPLELVCSEGYLCDSGSMTRSVIQEVRALWNRIFSIALFVEHVLLGTESHIPELSPLVTTYVSLLDKCLEEDSNLKTCRPFVAVMTTLCDCKDKASKKFSRFGIQPCFICHGDAQDPVCLPCDHVYCLRCIQTWLIP-GQMMCPYCLTDLPDKFSPTVSQ--DHRKAIEKHAQFRHMCNSFFVDLVSTMCFKDNTPPEKSVIDTLLSLLFVQKELLRDASQK-HREHTKSLSPFDDVVDQTPVIRSVLLKLLLKYSFHEVKDYIQNYLTQLEK-KAFLTEDKTELYLLFISCLEDSVHQKTSAGCRNLEQ-VLREEGHFLRTYSPGLQGQEPVRIASVEYLQEVARVRLCLDLAADFLSELQEGSE-LAEDKRRFLKHVEEFCTRVNNDWHRVYLVRKLSSQRGMEFVQSFSKQGHPCQWVFPRKVIAQQ---KDHVSLMDRYLVHGNEYKAVRDATAKAVLECKTLDIGNALMACRSPKPQQTAYLLLALYTEVAALYRSPNGSLHPEAKQLEAVNKFIKESKILSDPNIRCFARSLVDNTLP----LLKIRSANSILKGTVTEMAVHVATILLCGHNQILKPLRNLAFYPVNMANAFLPTMPEDLLVHARTWRGLENVTWYTCPRGHPCSVGECGRPMQESTCLDCGLPVGGLNHTPHEGFSAIRNNEDRTQTGHVLGSPQSSGVAEVSD-RGQSPVVFILTRLLTHLAMLVGATHNPQALTVIIKPWVQDPQGFLQQHIQRDLEQLTKMLGRSADETIHVVHLILSSLLRVQSHG----VLNFNAELSTKGCRNNWEKHFE-TLLLRELKHLDKNLPAINALISQDERISSNPVTKIIYGDPATFLPHLPQKSIIHCSKIWSCRRKITVEYLQHIVEQKNGKETVPVLWHFLQKEAELRLVKFLPEILALQRDLVKQFQNVSRVEYSSIRGFIHSHSSDGLRKLLHDRITIFLSTWNALRRSLETNGEIKLPKDYCCSDLDLDAEFEVILPRRQGLGLCGTALVSYLISLHNNMVYTVQKFSNE-DNSYSVDISEVADLHVISYEVERDLNPLILSNCQYQVQQGGETSQEFDLEKIQRQISSRFLQGKPRLTLKGIPTLVYRRDWNYEHLFMDIKNKMAQSSLPNLAISTISGQLQSYSDACEALSIIEITLGFLSTAGGDPGMDLNVYIEEVLRMCDQTA-QVLKAFSRCQLRHIIALWQFLSAHKSEQRLRLNKELFREIDVQYKEELSTQHQRLLGTFLNEAGLDAFLLELHEMIVLKLKGP--RAANSFNPNWSLKDTLVSYMETKDSDILSEVESQFPEEILMSSCISVWKIAATRKWDRQSR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63HN8-3", "uniprot_id": "RN213_HUMAN", "id": "Q63HN8-3", "name": "E3 ubiquitin-protein ligase RNF213", "aln": "-MECPSCQHVSKEETPKFCSQCGERLPPAAPIADSENNNSTMASASEGEMEC--------------------------GQELKEEGGPCLFPGSDSWQENPEEPCSKASWTVQESKKKKRKKKKKGNKSASSELASLPLSPASPCHLTLL----------SNPWPQDTALPHSQAQQSGPTGQPSQPPGTATTPLEGDGLSAPTEVGDSPLQAQALGEAGVATGSEAQSSPQFQDHTEGEDQDASIPSGGRGLSQEGTGPPTSAGEGHSRTEDAAQELLLPESKGGSSEPGTELQTTEQQAGASASMAVDAVAEPANAVKGAG--KEMKEKTQRMKQPPATTPPFK-THCQEAETKTKDEMAAAEEKVGKNEQGEPEDLKKPEGKNRSAAAVKNEKEQKNQEADVQEVKAS------TLSPGGGVTVFFHAIISLHFPFNPDLHKVFIRGGEEFGESKWDSNICELHYTRDLGHDRVLVEGIVCISKKHLDKY-IPYKYVIYNG----ESFEYEFIYKHQQKKGEYVNRCLFIKSSLLGS-GDWHQYYDIVYMKPHG-RLQKVMNHITDGPRKDLVKGKQIAAALMLDSTFSILQTWDTINLNSFFTQFEQFCFVLQQPMIYEGQAQLWTDLQYREKEVKRYLWQHLKKHVVPLPDGKSTDFLPVDCPVRSKLKTGLIVLFVVEKIELLLEG-SLDWLCHLLTSDASSPD---EFHRDLSHILGIPQSWRLYLVNLCQRCMDTRTYTWLGALPVLHCCMELAPRHKDAWRQP----EDTWAALEGLSFSPFREQML----DTSSLLQFMREKQHLLSIDEPLFRSWFSLLPLSHLVMYMENFIEHLGRFPAHILDCLSGIYYRLPGLEQVLNTQDVQDVQNVQNILEMLLRLLDTYRDKIPEEALSPSYLTVCLKLHEAICSSTKLLKFYELPALSAEIVCRMIRLLS-LVDSAGQRDETGNNSVQTVFQGTLAATKRWLREVFTKNMLTS--SGASFT---YVKEIEVWRRLVEIQFPAE---HGWKESLLGDMEWRLTKEEPLSQITAYCNSCWDTKGL--EDSVAKTFEKCIIEAVSSACQSQTSILQGFSYSDLRK---FGIVLSAVITKSWP-RTADN----FNDILKHLLTLADVKHVFRLCGTDEKILANVTEDAKRLIAVADSVLTKVVGDLLSGTILVGQLELIIKHKNQFLDIWQLREKSLSPQ-DEQCAVEEALDWRREELLLLKKEKRCVDSLLKMCGNVKHLIQVDFG----VLAVRHSQDLSSKRLN---DTVTVRLSTSSNSQRATHYHLSSQVQEMAGKIDLLRDSHIFQLFWREAAEPLSEPKEDQEAAELLSEPEEESERHILELEEVYDYLYQPSYRKFIKLHQDLKSGEVTLAEIDVIFK--DFVNKYTDLDSELKIMCTVDHQDQRDWIKDRVEQIKEYHHLHQAVHAAKVILQVKESLGLNGDFSVLNTLLNFTDNFDDFRRETLDQINQELIQAKKLLQDISEARCKGLQALSLRKEFICWVREALGGINELKVFVDLASISAGENDIDVDRVACFHDAVQGYASLLFKLDPSVDFSAFMKHLKKLWKALDKDQYLPRKLCDSARNLEWLKTVNESHGSVERSSLTLATAINQRGIYVIQAPKGG-QKISPDTVLHLILPESPGSHEESREYSLEEVKELLNKLMLMSGKKDRN-NTEVERFSEVFCSVQRLSQAFIDLHSAGNMLFRTWIAMAYCSPKQGVSLQMDFGL-DLVTELKEGGDVTELLAALCRQMEHFLDSWKRFVTQKRMEHFYLNFYTAEQLVYLSTELRK-----QPPSDAALTMLSFIKSNCTLRDVLRASVGCGSEAAR-------------YRMRRVMEELP------------LMLLSEFSLVDKLRIIMEQSMRCLPAFLPDCLDLETLGHCLAHLAGMGGS------------PVERCLPRGLQVGQPNLVVCGHSEVLPAALAVYMQTPSQPLPTYDEVLLCTPATTFEEVALLLRRCLT-LGSLGHKVYSLLFADQLSYEVARQAEELFHNLCTQQHREDYQLVMVCDGDWEHCYLPSAFSQHKVFVTPQAPLEAIQAYLAGHYRVPKQTLSAAAVFNDRLCVGIVASERAGVGKSLYVKRLHDKMKMQLNVKNVPLKTIRLIDPQVDESRVLGALLPFLDAQYQKVPVLFHLDVTSSVQTGIWVFLFKLLILQYLMDINGKMWLRNPCHLYIVEILERRTSVPSRSSSALRTRVPQFSFLDIFPKVTCRPPKEVIDMELSALRS-----DTEPGMDLWEFCSETFQRPYQYLRRFNQNQDLDTFQYQEGSVEGTPEECLQHFLFHCGVINPSWSELRNFARFLNYQLRDCEASLFCNPSFIGDTLRGFKKFVVTFMIFMARDFATPSLHTSDQSPGKHMVTMDGVREEDLAPFSLRKRWESEPHPYVFFNDDHTTMTFIGFHLQPNINGSVDAISHLTGKVIKRDVMTRDLYQGLLLQRVPFNVDFDKLPRHKKLERLCLTLGIPQAT-----DPDKTYELTTDNMLKILAIEMRFRCGIPVIIMGETGCGKTRLIKFLSDLRRGGTNADTIKLVKVHGGTTADMIYSRVREAENVAFANKDQHQLDTILFFDEANTTEAISCIKEVLCDHMVDGQPLAEDSGLHIIAACNPYRKHSEEMICRLESAGLGYRVSMEETADRLGSIPLRQLVYRVHALPPSLIPLVWDFGQLSDVAEKLYIQQIVQRLVESISLDENGTRVITEVLCASQGFMRKTEDECSFVSLRDVERCVKVFRWFHEHSAMLLAQLNAFLSKS------SVSKNHTERDPVLWSLMLAIGVCYHASLEKKDSYRKAIARFFPKPYDDSRLLLDEITRAQDLFLDGVPLRKTIAKNLALKENVFMMVVCIELKIPLFLVGKPGSSKSLAKTIVADAMQGPAAYSDLFRSLKQVHLVSFQCSPHSTPQGIISTFRQCARFQQGKDLQQYVSVVVLDEVGLAEDSPKMPLKTLHPLLEDGCIE-DDPAPHKKVGFVGISNWALDPAKMNRGIFVSRGSPNETELIESAKGICSSDILVQDRVQGYFASFAKAYETVCKRQDKEFFGLRDYYSLIKMVFAAAKASNRKPSPQDIAQAVLRNFSG-KDDIQALDIFLANLPEAKCSEEVSPMQLIKQNIFGPSQKVPGGEQEDAESRYLLVLTKNYVALQILQQTFFEGD----QQPEIIFGSGFPKDQEYTQLCRNINRVKICMETGKMVLLLNLQNLYESLYDALNQYYVHLGGQKYVDLGLGTHRVKCRVHPNFRLIVIEEKDVVYKHFPIPLINRLEKHYLDINTVLEKWQKSIVEELCAWVEKFINVKAHHFQKR--HKYSPSDVFIGYHSDACASVVLQVIERQGPRALTEELH---------------------------------------------------------------------------------QKVSEEAKSILLNCATPDAVVRLSAYSLGGFAAEWLSQEYFHRQRHNSFADFLQAHLHTADLERHAIFTEITTFSRLLTSHDCEILESEVTGRAPKPTLLWLQQFDTEYSFLKEVRNCLTNTA-KCKILIFQTDFEDGIRSAQLIASAKYSVINEINKIR-ENEDRIFVYFITKLSRVGR------GTAYVGFHGGLWQSVHIDDLRRSTLMVSDVTRLQHVTISQLFAPGDLPELGLEHRAEDGHEEAMETEASTSGEVAEVAEEAMETES--SEKVGKETSELGGSDVSILDTTRLLRSCVQSAVGMLRDQNESCTRNMRRVVLLLGLLNEDDACHASFLRVSKMRLSVFLKKQEESQFHPL-EWLAREACNQDALQEAGTFRHTLWKRVQGAVTPLLASMISFIDRDGNLELLTRPDTPPWARDLWMFIFSDTMLLNIPLVMNNERHKGEMAYIVVQNHMNLSENASNNVPFSWKIKDYLEELWVQAQYI----TDAEGLPKKFVDIFQQTPLGRFLAQLHGEPQQELLQCYLKDFILLTMRVSTEEELKFLQMALWSCTRKLKAASEAPEE----EVSLPWVHLAYQRFRSRLQNFSRILTIYPQVLHSLMEARWNHELAGCEMTLDAFAAMACTEMLTRNTLKPSPQ--AWLQLVKNLSMPLELICSDEHMQGSGSLAQAVIREVRAQWSRIFSTALFVEHVLLGTESRVPELQGLVTEHVFLLDKCLRENSDVKTHGPFEAVMRTLCECKETASKTLSRFGIQPCSICLGDAKDPVCLPCDHVHCLRCLRAWFAS-EQMICPYCLTALPDEFSPAVSQ--AHREAIEKHARFRQMCNSFFVDLVSTICFKDNAPPEKEVIESLLSLLFVQKGRLRDAAQR-HCEHTKSLSPFNDVVDKTPVIRSVILKLLLKYSFHDVKDYIQEYLTLLKK-KAFITEDKTELYMLFINCLEDSILEKTSAYSRNDELNHLEEEGRFLKAYSPASRGREPANEASVEYLQEVARIRLCLDRAADFLSEPEGGPE-MAKEKQCYLQQVKQFCIRVENDWHRVYLVRKLSSQRGMEFVQGLSKPGRPHQWVFPKDVVKQQGLRQDHPGQMDRYLVYGDEYKALRDAVAKAVLECKPLGIKTALKACKTPQSQQSAYFLLTLFREVAILYRSHNASLHPTPEQCEAVSKFIGECKILSPPDISRFATSLVDNSVP----LLRAGPSDSNLDGTVTEMAIHAAAVLLCGQNELLEPLKNLAFSPATMAHAFLPTMPEDLLAQARRWKGLERVHWYTCPNGHPCSVGECGRPMEQSICIDCHAPIGGIDHKPRDGFHLVKDKADRTQTGHVLGNPQRR-DVVTCD-RGLPPVVFLLIRLLTHLALLLGASQSSQALINIIKPPVRDPKGFLQQHILKDLEQLAKMLGHSADETIGVVHLVLRRLLQEQHQLSSRRLLNFDTELSTKEMRNNWEKEIA-AVISPELEHLDKTLPTMNNLISQDKRISSNPVAKIIYGDPVTFLPHLPRKSVVHCSKIWSCRKRITVEYLQHIVEQKNGKERVPILWHFLQKEAELRLVKFLPEILALQRDLVKQFQNVQQVEYSSIRGFLSKHSSDGLRQLLHNRITVFLSTWNKLRRSLETNGEINLPKDYCSTDLDLDTEFEILLPRRRGLGLCATALVSYLIRLHNEIVYAVEKLSKE-NNSYSVDAAEVTELHVISYEVERDLTPLILSNCQYQVEEGRETVQEFDLEKIQRQIVSRFLQGKPRLSLKGIPTLVYRHDWNYEHLFMDIKNKMAQDSLPSSVISAISGQLQSYSDACEVLSVVEVTLGFLSTAGGDPNMQLNVYTQDILQMGDQTI-HVLKALNRCQLKHTIALWQFLSAHKSEQLLRLHKEPFGEISSRYKADLSPENAKLLSTFLNQTGLDAFLLELHEMIILKLKNPQTQTEERFRPQWSLRDTLVSYMQTKESEILPEMASQFPEEILLASCVSVWKTAAVLKWNREMR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IBK5-1", "uniprot_id": "R213A_DANRE", "id": "A0A0R4IBK5-1", "name": "E3 ubiquitin-protein ligase rnf213-alpha", "aln": "-MKCPKCSHEALEKAPKFCSECGHKLQSQSYETTQGTPHDKSQTPSIVPQIT--------------------------NAEMDETGSESKSLEIQNANVSPKRPNENTSPNPKKKKRKKRKKEKKKKSGVS---EGPSSLTSDLSDISLTDKEKKMDTDQSSDSDCSSCIVEDTPTPAEPSSHLSPPENETAGPAQLSASALTTGSSKDGEESIGTTQKPVS--ASASKAPLGVDQQTKEEKVKCKDEGQKSLSAKAQHTPNANVDQNANVQSDANIDKDSQNVEPQK--------------SSSVKTKPSKSTVADPKKTESEKQKSGERDNENSTQPVSSPKLKRNQTEESQKMVFGPNSAPKKNRGSSADSAMKVEKKPAGGKKDSSADQKSKESEDTESQCVTLPKRNTRSTQHISSSDRLTIYFHAVLSKDFKFNPEEDLIFIRAGGPIG--NWEENLVELSVSRDLKEHGFLVEGKFICRKIDAEAVSIPYKYVVYKQ--KKNKYDYEYIYKLDAEVP--TNRCLFIKSHLLNDEGEWHQYDDIICAQPAKNMFEWVKKTIWSDEKKNVLQGRKIAGTIMLETIFDLLRSWSKINLNNFFSQLRQFYEIYRNPFVFEKKQTKWYQLDYDEKDVRELLKNFMLMHVTPELQKDSNE---KSKFIQEPLKAGLIMLYVWKQYDLKLDYGTLSRLCTAVCLPNLPKDEFLSLWTDITESFSVINSFSDMVEALISKLKAENMPRWIIVIPLLHLLKGTSKPFEQVITKVNSKYEQSWAGLQGLRSNILSPGPQ----ERRAMLNLMKTYGHLVEVDRLLIRSWMYLMPLDDLVECG-------SIFPVELLDILQLFTMKCP--NNISFTSSES----TAEALAHIQSQLLQHRYSCPDVDYGIQCIQAACKLLEKICSLVRYFGHSQN-FTDIPVACMNLVASVSGFAQTKQEADTFAEKTLVLLNDTKQTVRAWMRQTFKGRLLNSHLFSSHLTGTSFSTETEVWNNIIAIDFVCKDFIKEWRDTFTTDFEGKYQQEDHLDQIEAYCSNIEKLKVS--QPYLVNSVEKCALQAVSTICQTKSEWKLFARFNKFRINWRFGNLVSTIILKSWPKDDKGTYFEEEEAVLKHLLGWAAAKNIFQLHGADEKLIDQLSDEAKEKFAMATSLFTNVLNQLVTGKIKMKLLNHILEKKSVFLELLTLDCFSEEEQYKDIDAMKALIQTRQEEVKAIYHERALAGALIAMCHNVEEHVKVDYK----YLEDLYSNDMNEMDLDLFMDVHELNQIPTEASLEVPYFELQDDVRSMAEILNIFKDSYIFKLRWGNEAALFVERAEDEELDELDELP--------ITLDVLNEEIFLPCHAAYRNIYTSLKDGSIDFEDIDEIFR--AYKGKYEKLAAEVAIMSKQDFNDDQHWVQTRIQQIKQYHELHLAVESAKVVMMVKETLCLQGDFQVLEKLL--ITTHSDFKSERLDSIDNELIQAKNVLVDITEPRRLCLQELGHRKNFVIWVKEALEDINELKVFVDLASISAGENDLDVDRVACFHDAVLGYSSMLYDLKPDAGFSLFNEMLKKLWKALDNDSNLPKKLCDSARHIEWLKTVKDSHGSVELSSLSLASAINSKGIYVINAQNQ--KKLALENILKLHIMEEHDGGCETRVYSLEDLRDLQNKLMLMSGKGEQG-QCEVDQFAEVFASVQRLVSAFIDLYVAGNPLFRHWEANINCNSK-EACIIIDFNLGSVVSVVMVEGDVTEQLPEVCKKMESCLRFWQDFMDKQRSQHYYLNYYTAEQLVYLCHQLAHN--NMEEIDDQVLMMLSFIKPSCSTSDLRKAWHILQYDLIRKGPDQNDDLDFQTFVEVSSMTENESTEKSCPTSDDLIQQLGDASGSTKLGVIWNNYMRDMKAFLPDSLDVPSLGYLLEILANSHREDEGDMSQRDKTRTILRELPNGIASGRPNLIICPSEEILISCISIYMNSKNEPLPTYDEVLLCSATTPYEEVELFLRRCLS-AGYRGKKIYTMLYVNQLNYEVSYKVEKFFQNQNAHTT-NDYRLVLICESNKEHAYLPSAFSQFRLHLIPQQPIPSIQQYLHRHFAVPVGISSAAAVFKDRQNVGVVSSERSGVGKSLYIKRLYEKLKLNSKKPSQ-LKCIRLTEPKVDENVIIQSLISVLKKN---DLSVYHFDVTTMVKKGLHEFLFRLLILGYLMDSKGNMWKSSNKHLYVIEILRPGLSQNDRRAGAKVS----FNFLDVFPIVYCRSPKEVLELEMRMEEHPSFGLSDDPLMDDQEFRSEAYQRPYQYLQRFYNGINLDEFLYQG--VEGSHVECLQMLFEYCGIIDPSWAELRNFAWFLNLQLQDCEKSVFCDFSFVGDTLLGFKNFVVEFMILMAKDFATPSLSISDQSPGRLHEDFSSANEEDLAPFKIRKRWESEPHPYIFFNDDHDSMTFIGFHLQPNAQKGVDAVDPSNNRVIKQNIMTMELYEGLKLQRVPFNIDFDQLPRWEKIERLSRVLGIQWPL-----DPDETYELTTDNMLKMLAVHMRFRCGIPVIIMGETGCGKTRLIKFLCEMHRSGVATDNMKLVKVHGGTSSEMIYTKVREAEAMALRNKLDYGFDTVLFFDEANTTEAISSIKEILCDNSAEGQNLTENTGLKIIAACNPYRKHTDVMIKRLESAGLGYRVRAEETDEKLGSIPLRQLVYRVQALPPSMIPLIWDFGQLNDHTEKMYIKQIVERVAETHSIDSGYITVITDVLSASQKYMRTRQDECSFVSLRDVERCMQVFGWFYKKHLMLLSELDKFESIQRTEKTDQHPKDTDERNPILWSLLMAVGVCYHACLEDKEKYRKKICKYFPAAYS-PMKVMQEISVIQDIFLEGVPMGENIARNNALKENVFMMVICIELRIPLFLVGKPGSSKSLSKTLVADGMQGQAAHSDLFRKLKQIHLVSFQCSPHSTPEGIINTFKQCARFQEGKNLSEYVSVVVLDEIGLAEDSQKMPLKTLHPLLEEGCID-DQPSPHKKVGFIGISNWALDPAKMNRGIFVSRGDPDENELIESAKGICSSDVMILEKVRECFKPFAHAYLRICKKQEKGFFGLRDYYSLIKMMFAVAKACDQKPSAEQIVKAVLRNFSG-KDDVDAVTFFTSRLNIKPELETISAIELVRENVTAIGQ--------DEECRYLLVLTKNYAALRILQQTFFSDQ----CQPEIIFGSSFPKDQEYTQICRNINRVKICMETGQTIVLLNLQNLYESLYDALNQYYVTLGGQKYVDLGLGTHRVKCRVHKDFRLIVIEEKDIVYKQFPIPLINRLEKHYLDLNTLLKSEQKDIVKNLEQWVQCFTDVKNKHSVAPSARRYSPADAFIGYHTDTCASVVMQVTEQLKGQELSDPR----------------------------------------------------------------------------------KGILDESKLILLNCATPDAVVRLDCTSLFNVESEHLSRVYFEDQMHNSLAEFILSHIQQEGCSG-AFFTEVTTFSRLLTASETQQLQNVVQ----NIELLSLQQFDTEQSFLKKIKNYLENTT-GDKILLIQTDFDEGFQKLNVIASAKYSSINEINKFKKEGSGKIFVYFITKLPRMDG------GTSYIGFNGGPWKSIHIDDLRRPKDIVSDIKALQGLTISQLFEEKAEKVD---------ETEAMEVEDMYAGGEDEEDEEKMELEE-------------NNGCKDVLDTTALVRSCVQSAVGMLRDQTEGGMRSTKRVEILLMLLAEDQTLQAEFLKTLKTRLHSLLVAHDDN-TISAKSWVSREALNVDALHEGGTFRHALWRRVQAVVTPFLAQLVSVVDRDCNLDLLLDRNSGEPLKKLWLEIFRDDKFLSVSPYTR-TENNSATKTILVQNYMSVDRNKGCTMPFSWRIKDYLEDLWKHALQQ----EGHT--VKQFEEFFWKTPLGRYISEATNEMQMEFFYRYLQDFISMTMNVTSEVDFEVLRGAFTSSVNEVRIAHEAHES---EALSLVWIHVAYHHFKNRIQNLHRMMSLEPQISQMLLEN--RYASEGKELVLDVLAAVACIEYLEPQNLDGDDQSLAWLRRVKKLQVPVELVCSLESLHNRGDRCRQMVTNIQHGWRRIYSLVLFVEHMLLGVGDLQQKLKPVVLEHTQLLAQVLEQDSNLKKKKPFEAVITVLKTCKDKASQRIIRFGLQLCPVCMGDPRDPLSLPCDHIYCLTCIRQWLVP-GQMHCPLCVQEVPDNFELKPSD--ELRRLISQNASFRMRCNAFFIDLVSTMCFKDNTPPSKDIILHLLSLLMVEASSLPPFKGRDRRFLTKALSPFDDSVDKNPVVRSVVLKLLLNYSFDHVKDYLQQHLTEVEQSKILEETDKAELYCLYMNCLEDSMYDRTQWHTVAEQQNCFLEETRFLLEFLQS--DSVSAHTATVEHLQRLARVRLCLDMAADLLVANAGIHDDPSAFIQAFWNNVVNLCRQSRNDWYRVYLIRKLCSLQGVECVKNLLLQET-YRWLFPQEILEMN----QDDSQIDQYLACGADYKTIRDAVAKFMLDLHINGIQKAIEDCNCTPMKKAVYVLMAFFREVTSLHRTGNPNMHPKPEHCAGLEHFIKNSAIFVNNEMKAFAEKLVRNQLG----ALRVRPHMPSRDLSLVEVTIHMAAVLLCGNLLLLQPLQKLALSPNNMMASFIPTMPDDMLAVAQ--QAMGHLQWYFCPNGHPCTVGECGQPMEVSRCPDCDAEIGGSNHRPVDGFRAMQIQADRTQSGHILGDAQRRDLPDMQDTKNMSPAPFALLRLLTHMSMLIGTQNNPQSIMQIIKPAVVHPDAFLMQHLLKDMEQLSKALGKGVDDTVSTIHLAIHSLLEPHQTS--QWPDPYDPNLSTKDARNGWENAMNNDVITHHLKVLEHQLKEVNAFIREDERVSSNPVMKLTFGEPGRFLRSLPQNSLIHNSSIWSCRNKVSLMSLTHIVEQNNGRDTLPVLWRFLQREAELRLVRFLPDILVLQRDLVKKFQNITDLTYKTIREFLQDQKAASLTAWYEKRIKIFLTTWNQIRVSLANTGEIKLPADYTEKDLGLDADLQVLLPQRRGLGLCSTALVSYLITIHNDLMYTVEKHTGD-DSDYKISPAELTELHVIRYEYDRDLLPLVLANCQYSMECGQETLLEYDLPKIQQQILTRFLQGKPLITINGIPTLVNRQDRNYEIIFKDVKGKVQQELLQPLTQYDLVKELQSYSDVCEALSTVELAVGFLAMTGGEPNMQLGVYLKDVLQMTDHMATHVFKALSRCSLKHCVALWQLLSSLKSETMLRLKRDPFVGISKEYKQPLQEEHKRLLTSFFTKSSADAFLLEMHEFLLLVLKSP--KATDTYRPDWRLKHTVVSYMERKDLDVPPEVEEFFPKEILLSEYTSTWNFSVNLRQKRSQS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB13A8X0-1", "uniprot_id": "A0AB13A8X0_DANRE", "id": "A0AB13A8X0-1", "name": "RING-type E3 ubiquitin transferase", "aln": "MTRKRKSGKKGKPLAQKKEAQKRGGSTSSSTTQKEGAQKGDGSSSSSTTQKD--------------------------GAQKRDDSTSSSSTAQKEEGQKSDGSTSSSTTNKEGAQKRDGSTSSRLQKKGP-------------------------------QKRKGSTSSSRAHSRSRSKSKQTSYPSQARSRSHGQHNISTTESGPLSKEAQTQTSASLLVDKDTQTETVGQASQQTQTEINGNTETAEVSQPPQLSHEDVEMEGTVQPRTKGSESDGEKEESVKR---------------KKRKLSEIGEPAKETEDSTKLSHECEEKVGDNQKNEDTNKHYGGDSLKDLKSVTEEPKSYAAAAATGKTGKVSKEQTNQIEANQDSTMESKSTQRKPSPVRAPAGPP-------------MLTFYIYAVLDKRFRFNEQYDSLFLDYG--------NGNIKLQMKHFNIGKDGYLIEATFSVEDSAVRGGTIQYKYVVQQR---------------QNQKSEIAVRYIEVPSYTTEK--EFHLYEGYISCSSTVSITEWMMSLFHS-EQKAVYKGWETSAHVLLDRIFLKWHPSNEESNMTFVQHLRSYKNAFESGFVEFPG--NYTPFPIKVSELISAKLRMILKKESEALR----TSESLDGVKSEALSVALSVFKVCCGCDVDLSLKDWGKLCQVVSECMGSFG---------EIQTTQTAPFINTVTGLMNLCAKKLITEVVLLVPVLHLLRNSEVNEAGPGSSMD---EQRWTGLENISYQSFRERIRGLPDKRRMILKLIKDNLPMTKDNPKLLKSWLSLVAFEDVSEFVQLTGSFPELLIQSLMCRIIEAEKNTDANRTEKNLEVTG------KVLNLLLKSIKKDRERIMKTEQLKLILQCCCNVHKSVCKTARLVPQYKVTVLSFQLLLKMAEIVYDGFFKGGEQMKQHQNEVLSKLNIIQEDFRKWRVELLLKPLMQT-------TGFTYPREMELWNDLYGIESSIPGVTERWKGFLDHDLRRRISQISDTDKIVVYVLVTSAKAVENSHANIQSCLKELCEAAIKNQCQSKKEGTLLCHLFSKTISWPVLSSIIVESAACFG-----------EDHKGRLLDPQSAINFFLSQ--DKWNEWKLEDGASQLIAESQSFLGRLIQTLCQGSIPLGHLKTIFKYKTQFQKLYNQYKNN-NKEMNVSISVSDLLSQREDDLKAFEQQKGYMTNLINMLGKISDVINVPELSSLEEIAKTNVQEVALDKLVEVETYFSKDDLKKNNTRRVLFYSDDQQVQDMAREMHDVNSSNLILSFWQEKAKDYFMAGPELLS---------------LDLTEIYEDIWTPCLTKFLNFGNRIAVGQACFKEVEEALVGCGETGEGDRLKKEFMLMATMLDGHNENWPEQRLKQIREYRCLYDAAESAEVILKLKDRLGLQGDFSHIHSLT--LVRDDSFKQNTLGSLSEDLIKARQKLADVERRHTACLEAFLKSDTLIKWIKAEIPSLKELKVFMELATISAGENDADIDRLASFETAVMGYAPLLYSLPQNVGFEEFFDYAKQVLDTLNKDEKLGDKLVDSNRWLDWLKGLRETHGSVEQSSLSLASAINTGGVYHVGWPDDFNGKTGLDNIFYVKVTKNN----EEKTYRLNELLELQNKLMLMSSKGEKG-KEQVIKFTQVFEGIQRMGRILLQLHRSGNMLFRNWAAEITCNHQNQPCIQVKFPL--LSKCIVYQGEVEEELQKLSRSLEDFHKDWCNHLTKMRSQYYPLNHYSSEQIVYLCEWINSINIKKKPVPQQVWHLLTPIKPDCMLNDIKEAFEIATEPQSILQEDT------AEELGPNSDFDLP------------LSFSLLDVSTECLEDLWKQFKENMSGFLTHHVDVETLGRFLSNLSNMNQLH------------IKRKIPSFLQEGRPNLVQCPAAELMSTTLSFYMESPENPLPTTDEVLMCQEETTEEEVEIFLRRCLGGAASNHKKIYTLVNPGSMSYDVSVALVEYFETQEVCAG-PYYRLVMVCPVN-QDRYIPSFFSNYKVQTGITISAERSQKYIRHHFKISYELATHSSVYPERLSVWMIASKRPAVGKSLYVRRLFEKFKG--EFPRATLLTIRLIDPYIDMDGFVQTLSERLAPLRQQDPVLLHIDVAAVCHG-LEEFLFKLLILECISDSKGTIWRRNKAHLVVIETLQRGHKTQTKME-------PSHGFLNTLPTIFCRPPKDIKEIMKTNESFR----SLDPLMDKEEFESEDIQRPYQYLRRFNRSMNLDRFTYQAHSVEGDPVDCLHHLLSNYGLKDPSWAELKHFTWFLNLQLKDCEKSLFCDSDFCGETLSGFKDFIVKFMIHMARDFASPSIDISDQSP-----SFFSKNEDEEEILSFRKRWENESHPYIFFNADHVSMSFLGFHVKQN-GTILNAVDSKSGKVLMRNVMTQELFSDIQRQMINLSKDFDDLTREDKLQKMSFVVGAEKGCEKGKFDPDPTYELTTDNVMKMLAIHMRFRCEIPVIIMGETGCGKTRLVRFLCDLQREGRDVENMKLVKVHGGTTSETIYKKVREAEELAQKNRQKYKLDTVLFFDEANTTEAIFAIKEVLCDKTVKGYPLKKNSGLKIIAACNPYRRHTTKMVDRLERAGLGYRVKAEETEDRLGKVPMRQLVYRVHPLPPSMVPLVWDFGQLSDSTELSYIRQIVKKKMRDHRLPLSCQNVITNVLAASQKYMRNQADECSFVSLRDVERSMGVLLWFYNHRDIFFPSQDFPRFEN--------------VQMVLKCLVLAVGVCYYPSLENKRPYLATISKCFPDQFNSEESLEQEIASCQDFLLKNIQTRETIAKNMALKENVFLMVVCIELRIPLFLVGKPGSSKSLAKTVIADAMQRQASHCDLFKKLKEVHMVSFQCSPHSSPEGIIGTFRNCARFQKDKNLDEYVSVVVLDEIGLAEDSPQMPLKTLHPLLEDGCIDSDNPESYMKVGFVGISNWALDPAKMNRGIFVSRWDPSEKDLVETAEGICSSSQPVLLKIKHLLSKLAKCFLSICKTDSEQFFGLRDYYGLIKMLFDTVKCSDQEPSDKELAEAVLRNFSGQRDGFDPLDYFKDIFQNIQNVQRPNTLNMIEQNLDHHID---------KECRYLLLLTTNNAALYIIQHHIFSKENYTQKCPEIVFGSGFPKDQEYAQICRNVSRIKACMETGRTVILLNLLNLYESLYDALNQYYVYFSGQQYVDLGLGSHRVKCRVHRDFRLVVVEDQEKVYKKFPVPLKNRLEKHKVDRSTDLAPWQHRVLEKLKKWAREFSKIQHSDSSEAN---FSVTDAFVGFHGDACASALLQALKKIDKLHHNKEENREESEAHHIDREFTEFQEKVNKFPDEAQEDDASMEVDKVQDAEIDEEMETLEDDSDLVKMVEGPVFVETRDKIESNKTMDEEEVYEIAKSFLLNCSTPDSVLRLKYSEFGNQETEELQKMYFHLQTHQSLRDLLNNHLNKTNQDK-NRFLEVTTFSNLLTGADVRNLGPALGLSTERFLLLSLHQFDTEASFCNKIQSFLRESGPSVHILLIQMDMEESLCKNELIASAKYCTMNEILHLK-SDECNIYTVFITKLSRIGEQCTSITGDKYIGFQGGVWLSAHIDDLRDSDDLCLNLKAFCGIPISQLIS------------------QTIESDVKES---DEMNTNRQQSEK---------------GDSVHLHSLSLLRSCTQKAVSLLRDTDEKTSRSMERMNILLGLLACDPGRTGARFQQVLLKRLVFALIQKEELIPNAKDWVYKVAKNHEALQECGTLRHTLWRYLQDFLTPVLARILEVIDRDCNLYQLYGEGLSEGLTQFWLDIFEDQQLLDLIPSQNTRAPDQEINVQCHLFVGEVEQP--CAAPYSWLIKTYCQSLWEESEFVRSSEQDIKARIQQFVSAVSGSRLGSYIQKLSDVENVELGQRYLTDYVLLAFKVNSEDEHWVLQSAVLGCVFTLQTMMSVSPE-----LSPSWIHAAAQIYNPRMDTLSHVLQLNPQLVSLIQQERPKRESP--DMCEDILAVGICVEETKLLPVTSLTECLTFLQRVEQLQPCIERVLSPDYSALCSPGCLKYLETIQSVWQGILLVAVFIEKVVIKMKKGDERIIALTLKHCSQLHGLVEGSPDFRSKDNLQQIIRILNDYHEESISSELRYGVK-CRVCLMELSEPFALPCEHVFCRSCLRRSMEREEAQHCPVCREPLSNNYQPTVSTTLNYSFALKQHKEIIKCCNTFFLEVVSRFCLTDDQDPPDDLVELLFSLLISAQG---------DVYKTRELTPFLECVDQSPVVRSVLPKLLMQYSLKQVKKHIQSYLEDLEN-KLLDKEDRTELYRLFVNCFQDTLLCSDSNG----DHKHLRENTNFLSRLARKQTPSRQN--DPAEFLMSMARLRMCLDSAAYILSKAICQKNNFVEAEFKFMEQVKAVCDYCDNDWYRVYLLRALNRQAGMDFLQAL-INSTDYEWIFPAEMMRLHR---LIPAEVDRFLCCGQSYRALRDGVGESTQVGTTDGLKEALQASVGSSPLKNALLTLAVFRQVTCHFMSPERTLHPQEQQISILEKVIRDN---MSGHAREFCTALLSNHIGGPGSNLRLGTGVPAQRRPVLELLVHACTVFYSGN-RLISPLFNIASQPQNMTGAFLPTMPDDHTSEAKQWLSEKKLKMYFCSNSHACFVGECGRPMAKSKCATCGVEIGGEGHIPVPGFTEAYGDYDRTRPGHILGQARTRSEAPNRK---LTLAQSCVLRLCLHLAMLQGLIHYQQGIRNMIHPEVSDVYQFLWQHLEKDMEVLGKTLTLNIDDSAIVIHLIFSRFLQTTPVAN--------VDLSTRKSREQWEITVCKTAISPVLQNLDRELNNAQDLIAADNRLSNSPLVKVLRGDP-QRMLQLPANCPTEHSAFWSPSSVLAVESISQQIDQ----AQAPLLTLFVQKVHYIRQLDCLPALAALLSDLIKVLPPGSETQNHTIASLLHCIPAGHQKKLMSERVEIYMKVWNQLRMEISSNASLGLDSTHCEKDITSESSGQFLFPSRKGAGSCLHAVIDVLSETHNSLVREARKLCQQTDSDYKVPLAVLSKSQLALCHPEREFLPLVLANCHYTLEKGQQTVSSYDHQGIERELSRRFFAGKPRIQTD-TEKYLRRHHQNFTEVLNEVRAKIPQKVSGSSCSTNQHQVHHGASFGGEGHHFFSRSR----QSSGGTYLG-------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. : . : * :: . : . .. .* . : . ... . ..:: . . ::.. : . .: . . .: . . . . .. .:. : . . . .. :. .. . :: : . : :. : . . : : .. :: ... :*. ::*::. * ** : . :: * : :: . *:*. . * ****: . : . * : : * . ::* * . : . : . : . :* : :* : :. ::*: * :. . . .*. :: .: . :: : : :: . : . . .* :: : :. : . ** : . : : * : :*:** . *: *:.*:.: . : *:::: : : *::**: ::.:. : . :: : . . : : : : : : . : : :*. . : . : . . : . :: : * : :: : : * :*. : * *: : *:. : : :* : . : .:: *:.. **::.. . . : . .: : ** . :.* :: :: . . . :. : *.: .: * *.* : *: *:: :. * : : . : :. *.::: : ::: *: .:.. ::* : ::: * .. . .: . :: .** :. ...* :: * : * : : * : : :: *. : .: : *. : ::: : .: * :. :*.. . . * . *: **::*: *: *. :*:*:: :: * : ***. :. * ..* : *..:. ::*:*:: * *: . : *: : :: *:: : .::*****::**:******* *:**:*.*. ** **:.:*:.: ..*. * . ::: :*::*. * ** ** * ::*** :.::***** ***:**:*** *:* : . * . :.:: : : . : * ::: :* *******.: ::. : :* *::** .:**: ::.*: :** *** * * * : :.* : . : *:* : * :.:.:* * : : * :: ** *::**:***. : : . :*: ** .* :: .* . * : : : .**. :*: :** * *: : * :* : *:***: * *:: : ::.**: :**** ****:* *. *** ::***** :*:*::: ..:.*:*. : *.. . *:**::* :. *:** **:.:: . * *: *: :. : ::*: : * :::*:*..******:. *. *:* . * *** :* :* . .: :* * : *:*::: : : ***:**** : * :*.:* . ** ::* . : . **: :* : **.**:: :: :* ** ** ** *******:** . :** * *: *** :**: :: *: :***:**::*: *** **:*** *:**. * *:** ***.*:* **: **:***:*:: ***** : *:: :.:*****.*.***:*** *: :*:*:***:: * ::*:. ...:: :::** :*:..: * : :. :**.*.* .*::::. .:* *** ********::*:**:.***** ****************::**.:::* . .:.:*********:.. **.:*::** * *: .: ::*:*********:*: .***:***. . * * :::**::********:*: *: *** ******* *** ::**.:*:*******:.****::**:******.* :* **:***:: : **::**.*** :**. :**.*********.: *: **:.: ::: . : :* .*::*:****:..**.* * *.: :* :. : :*:: **::* . .**:* *******:**:****:***************:* ::**.** *: .:**: **::*:*********:*:***.**::*****:.*:* :*********:****** :***********:***: *:* .: :***:******************** .*.*.:*:*:*:*****. : ::: : :*:.: :*: :.: ********.****:* .*...: * .::..******** :*..:.: * : : ..::::.:*: : :.****:** * .** *:*: :*. ***:***.**:****:*:***:.*:* *****: ::**** *************** :.**:*******:******** ***:*:*::: ***:**:** ****** :* .* * *: ::::* *.. * .:: . :* :*.*:*:* .:***.::*. :: .. . : : :: :**:*:***:*:**. .: . :: *.: *: * *:*: ::: *:. . * *:****.***. : * : . :* *:*:*** ** :.::. * :. ::*::* *:::. . :::***** :*** : : . ::. *:***.*:. * *:**:** * * ****** . : ::. : :.****: : :* : : * : : *. . *.: *::**.* **.:*** * *. .*: :** ** : . :: : : :.:. .*: : * * :**:* **:**:**: :* :**.** :: :*** ** * . .:*: *: * :*.: . . .: . *:** *: * :.** .: . ::* . . : ** :: : : :: ** *:: :::.*.:. : .*: *. .. :: . . :* *:* * : :. *::.: ::: : **: : : . :: * :*. * * : . .:*: *::*. :* : * . : :: * * .:*:*:::: . .: :. : * :. ..:.:. : :: * :: : . *:*:: * :* : :*..***:*:.* *:: : ** * :.:::. * :.:: : **:**:::** :*:.*: * ..:: *:***: *: *:** : **:.**:***: ***::**:..** ::*.:* ::: * : *::*** *::.*::*:: . : : *: .** ..*.* :**:*:*** ** :* : : ::* .* ***:****:* * *:: :: : .*:** .:: : . :*::* * .*:::**. .: .: *: . . : . . ::.: :*: . : : .:** :: :.:.* : . *. *: * : *: . .: *: :* .::: .*: ::.** ::* * .* :*:****:* *: . .: * *...*.* *****:** * * * :** .* * ** . ***:.**:**..: . . . : ** *:::* * : *.: :*:* * . ** **: :*:* * * * . *:: .:** : :*. ***: *: ** . : *: *:: * : * *:*:*..*: *: *:* : ** :. . * :** ::: : : ::* *:* *:*: :* : ** : .* **:* : :* :: : .*: :::..** :* .: ....: * : .*: ::. :.::* *:* * * *::. * **.:: ..* : :..*.: : ::. :: . :*:: **:*:**:* :: * :* .:* *:::: **: *** : . . : *:. *: :: ::: *: *. :. * * .. : :.* . : ", "identical_positions": 1204, "similar_positions": 1452, "identity": "21.94%" }, { "cls_id": "homologset.agr.RGD:1308169", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5HZV9-1", "uniprot_id": "PP1R7_RAT", "id": "Q5HZV9-1", "name": "Protein phosphatase 1 regulatory subunit 7", "aln": "MAAERGAGQQQSQEMMEVDRRVESEESGDEEGKKHGGG-IVADLSQQSLKDGVERGAEDPEEEHELAVDMETISLDR--DAEDVDLNHYRIGKIEGFEV--LKKVKSLCLRQNLIKCIENLDELQS--LRELDLYDNQIKKIEN-LEALTELEVLDISFNLLRNIEGIDKLTQLKKLFLVNNKINKIENISTLQQLQMLELGSNRIRAIEN--IDTLTNLESLFLGKNKITKLQNLDALSNLTVLSMQSNRLTKIEGLQNLVNLRELYLSHNGIEVIEGLENNNKLTMLDIASNRIKKIENISHLTELQEFWMNDNLLES-WSDL-DELKGARSLETVYLERNPLQKD--PQYRRKVMLALP-SVRQIDATFVRF---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UM45-1", "uniprot_id": "PP1R7_MOUSE", "id": "Q3UM45-1", "name": "Protein phosphatase 1 regulatory subunit 7", "aln": "MAAERGAGQQQSQEMMEVDRRVESEESGDEEGKKHGGGGIVANLSEQSLKDGVDRGAEDPEEEHELAVDMETINLDR--DAEDVDLTHYRIGKIEGLEV--LKKVKSLCLRQNLIKCIENLEELQS--LRELDLYDNQIKKIEN-LEALTELEVLDISFNMLRNIEGIDKLTQLKKLFLVNNKINKIENISNLHQLQMLELGSNRIRAIEN--IDTLTNLESLFLGKNKITKLQNLDALTNLTVLSVQSNRLAKIEGLQSLVNLRELYLSNNGIEVIEGLENNNKLTMLDIASNRIKKIENISHLTELQEFWMNDNLLES-WSDL-DELKGARSLETVYLERNPLQKD--PQYRRKVMLALP-SVRQIDATYVRF---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15435-1", "uniprot_id": "PP1R7_HUMAN", "id": "Q15435-1", "name": "Protein phosphatase 1 regulatory subunit 7", "aln": "MAAERGAGQQQSQEMMEVDRRVESEESGDEEGKKHSSG-IVADLSEQSLKDGEERGEEDPEEEHELPVDMETINLDR--DAEDVDLNHYRIGKIEGFEV--LKKVKTLCLRQNLIKCIENLEELQS--LRELDLYDNQIKKIEN-LEALTELEILDISFNLLRNIEGVDKLTRLKKLFLVNNKISKIENLSNLHQLQMLELGSNRIRAIEN--IDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQNLVNLRELYLSHNGIEVIEGLENNNKLTMLDIASNRIKKIENISHLTELQEFWMNDNLLES-WSDL-DELKGARSLETVYLERNPLQKD--PQYRRKVMLALP-SVRQIDATFVRF---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q32PL1-1", "uniprot_id": "PP1R7_DANRE", "id": "Q32PL1-1", "name": "Protein phosphatase 1 regulatory subunit 7", "aln": "-MATLSVGEPQE---MEVDRRGESEESGDDETK------------RKSLNGEVDSLQAPSTVPEESPVDMDTITLDP--EEEDVDLVHCRIGKIEGLEV--LLKAKTISLRQNLIKRIENLESLVS--LRELDLYDNQIRKLEN-LQALTELEQLDVSFNLLRKIEGLDSLTKVKKLFLLHNKIASIANLDHLTSLQMLELGSNRIRVIEN--LDSLSSLESLFLGTNKITQLQNLDGLHNLTVLSIQSNRITKLEGLQNLVNLRELYLSHNGIEVMEGLENNKKLSTLDIAANRIKKIENISHLTDLKEFWMNDNQIEN-WADL-DELKNAKGLETVYLERNPLQKD--PQYRRKIMLALP-SVRQIDATFIRF---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VEK8-1", "uniprot_id": "Q9VEK8_DROME", "id": "Q9VEK8-1", "name": "", "aln": "------MG--------DADRAMNEPEAAK----------------------TVSGIQVIP--AEDVASIEDIITIDP--DCYELDLNHRRIEKLENFEP--LTRIERLFLRWNLIKKIENLSSLKT--LIELELYDNQITKIEN-LDDLPHLEVLDISFNRLTKIENLDKLVKLEKVYFVSNRITQIENLDMLTNLTMLELGDNKLKKIEN--IEMLVNLRQLFLGKNKIAKIENLDTLVNLEILSLQANRIVKIENLEKLANLRELYVSENGVETIENLSENTKLETLDLAKNRLKGIANLEKLELLEELWLNHNGVDD-WKDI-ELLKVNKALQTIYLEYNPLAKD--VRYRSKLRDILP-QLQKIDATLCKVPGT", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36047-1", "uniprot_id": "SDS22_YEAST", "id": "P36047-1", "name": "Protein phosphatase 1 regulatory subunit SDS22", "aln": "-----------------MDKNSVNKDSEE--------------------KDERHKIEVVDDTNPDFITADSELTQDLPDDVEVIDLVHLKIKSLEDLNLYRFKNLKQLCLRQNLIESISEVEVLPHDKIVDLDFYDNKIKHISSNVNKLTKLTSLDLSFNKIKHIKNLENLTDLENLYFVQNSISKIENLSTLKSLKNLELGGNKVHSIEPDSFEGLSNLEEIWLGKNSIPRLINLHPLKNLKILSIQSNKLKKIENLEELTNLEELYLSHNFITKIEGLEKNLKLTTLDVTSNKITSLENLNHLSNLTDIWASFNKIDQSFESLGENLSALSRLETIYLEGNPIQLENKTSYRRKLTMNLPPSLQKIDATYIRG---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: . :: . : . :. * : :** * :* .:*.:: : . : : ** ***: *.::. * : :*::***:* ::.. :: *..* **:*** : :*:.::.*. ::::::: * * .* *:. * .* ****.*::: ** :: * .*..::**.*.*.:: **. * ** :**:*:*:: *:*.*:.*.**.***:*.* : :*.*.:* ** **:: *::. : *:.:* * ::* . * ::. : .: : *. *:*:*** **: : ** *: ** .:::**** : ", "identical_positions": 97, "similar_positions": 124, "identity": "25.66%" }, { "cls_id": "homologset.agr.RGD:1308170", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LDN3-1", "uniprot_id": "A0ABK0LDN3_RAT", "id": "A0ABK0LDN3-1", "name": "CD180 antigen", "aln": "--------------------MALDISCFLLVALFSASCQAIGSSDQRCTEKEVNK-TYNCEHLGLSEIPGTLPNSTESLEFSFN--------------------------ALPTIQKTTFSRLVNLTFLDLTRCQIYWIHEDTFQSQHRLETLVLTANPLIFMAETALTGPKALKHLFFIQTGISSIEFIPVHSQKALESLYLGSNHISSIRLPKDFPTEKLKVLDFQNNAIHHLSKED---------------VSSLQQATNLSLNLNGNDITGIEPGAFKSTV-----FQSLNFGGTQ---SLLVIFKGLQNSTIQSLWLGTFEDIDDDEDISSSMFEGLCEMSVERIN------------------LQKHHFFNITSNTFYCFSG---------LQELDLTATHLTELPSGIVGLSKLKKLVLSANKFEN--------LCQISASNFP------------SLTHLYIKGNTKRLELGSGCLETLEH-----------------LRELDLSHDDIETSD-CCNLQLRNLSHLQS-------LNLSYNEPLGLRTEAFKECPQLELLDLAFTRLHVKDAQSPFQNLHLLKVLNL---------SHCLLGSSN---------------QHLLDGLPALRHLNLQGNRFPNGNIQKTNPLQALGSLEILILSF-----CDLSSIDHQAFINLKIMNHVDLSHNRLTSSSIEALSHLKGIYLNLAS---NRISIIPPSLLPVLSQQRTINLRQNPLDCTCSN--IYFLEWYKENMQKLEDIEDTFCANPPLLRGVKVSDVMLSCSMAA-VGIFFLIVFLLLFAVLLIFAVKRFLRW--KYQHI-------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62192-1", "uniprot_id": "CD180_MOUSE", "id": "Q62192-1", "name": "CD180 antigen", "aln": "--------------------MAPDISCFFLVALFLASCRATTSSDQKCIEKEVNK-TYNCENLGLNEIPGTLPNSTECLEFSFN--------------------------VLPTIQNTTFSRLINLTFLDLTRCQIYWIHEDTFQSQHRLDTLVLTANPLIFMAETALSGPKALKHLFFIQTGISSIDFIPLHNQKTLESLYLGSNHISSIKLPKGFPTEKLKVLDFQNNAIHYLSKED---------------MSSLQQATNLSLNLNGNDIAGIELGAFDSAV-----FQSLNFGGTQ---NLLVIFKGLKNSTIQSLWLGTFEDMDD-EDISPAVFEGLCEMSVESIN------------------LQKHYFFNISSNTFHCFSG---------LQELDLTATHLSELPSGLVGLSTLKKLVLSANKFEN--------LCQISASNFP------------SLTHLSIKGNTKRLELGTGCLENLEN-----------------LRELDLSHDDIETSD-CCNLQLRNLSHLQS-------LNLSYNEPLSLKTEAFKECPQLELLDLAFTRLKVKDAQSPFQNLHLLKVLNL---------SHSLLDISS---------------EQLFDGLPALQHLNLQGNHFPKGNIQKTNSLQTLGRLEILVLSF-----CDLSSIDQHAFTSLKMMNHVDLSHNRLTSSSIEALSHLKGIYLNLAS---NRISIILPSLLPILSQQRTINLRQNPLDCTCSN--IYFLEWYKENMQKLEDTEDTLCENPPLLRGVRLSDVTLSCSMAA-VGIFFLIVFLLVFAILLIFAVKYFLRW--KYQHI-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99467-1", "uniprot_id": "CD180_HUMAN", "id": "Q99467-1", "name": "CD180 antigen", "aln": "--------------------MAFDVSCFFWVVLFSAGCKVITSWDQMCIEKEANK-TYNCENLGLSEIPDTLPNTTEFLEFSFN--------------------------FLPTIHNRTFSRLMNLTFLDLTRCQINWIHEDTFQSHHQLSTLVLTGNPLIFMAETSLNGPKSLKHLFLIQTGISNLEFIPVHNLENLESLYLGSNHISSIKFPKDFPARNLKVLDFQNNAIHYISRED---------------MRSLEQAINLSLNFNGNNVKGIELGAFDSTI-----FQSLNFGGTP---NLSVIFNGLQNSTTQSLWLGTFEDIDD-EDISSAMLKGLCEMSVESLN------------------LQEHRFSDISSTTFQCFTQ---------LQELDLTATHLKGLPSGMKGLNLLKKLVLSVNHFDQ--------LCQISAANFP------------SLTHLYIRGNVKKLHLGVGCLEKLGN-----------------LQTLDLSHNDIEASD-CCSLQLKNLSHLQT-------LNLSHNEPLGLQSQAFKECPQLELLDLAFTRLHINAPQSPFQNLHFLQVLNL---------TYCFLDTSN---------------QHLLAGLPVLRHLNLKGNHFQDGTITKTNLLQTVGSLEVLILSS-----CGLLSIDQQAFHSLGKMSHVDLSHNSLTCDSIDSLSHLKGIYLNLAA---NSINIISPRLLPILSQQSTINLSHNPLDCTCSN--IHFLTWYKENLHKLEGSEETTCANPPSLRGVKLSDVKLSCGITA-IGIFFLIVFLLLLAILLFFAVKYLLRW--KYQHI-------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P6U9-1", "uniprot_id": "A0A8M1P6U9_DANRE", "id": "A0A8M1P6U9-1", "name": "", "aln": "----------------MESFFVFYMSFYSILFHFLVFNEATPWARRHC--QQITK-GYDCNDMDLQSIPDEIPNSVQILQFSFN--------------------------YLPALYNSTFQRLKSLRSLDVTRCSITFIYEDVFTYQPHLEVLLLTGNPLVFIASTAFSGPLALKYLSLVQSKIKQLSDIPSENLAYLEVLDLRGSNIRSLNGLSNFRWQNLKSLQLDLNFIDRISFND---------------LQPFSNLAGVSISFKGNDFIYIEPGAFHSLN-----LSSLDFSGCLNKMNISSLLKGLEGIKTNRLNLGLYETDSN-VYIASAALQSFCNIFVSDLD------------------FQLQHFLDLNNSTFHCLEG---------LKKLDLTRAHLNALPLNTTGLSTLSHLILDENQFKD--------VCQSNTRNFP------------MLTHLSISGNLKKLTFSNRCLDSLGL-----------------LEELDLSVSLVNPREPCCNNQLFGLGELKL-------LNLSYGSPMFWSSKPFNVTPKLEHLDFSHSVYTLLNDSSPFSNLQSLRTLNL---------SWSNTDLTN---------------VHLFVGLKALQHLNLRGNAIQGEVLTQTELFKCVPLLETLVLSA-----CKITSFDENLFKGLRHLNHIDLSENKFVKLSTSGFYSLDFLKLNFAR---NDITTVDVASVADLGEEGSVDLSYNPLVCNCSN--FEFIHWVKKNKVKVKHLMETFCNG----TGTRIIDAKLQCDLPVGVLVFCAVLAAVLLASAIFLLIRRVRKYS-IYTNL-------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A6M3Q7U5-1", "uniprot_id": "A0A6M3Q7U5_DROME", "id": "A0A6M3Q7U5-1", "name": "", "aln": "MPDHTRVTATTRSRPWLCGAIPVLLLLLLTLVILPPETTAFCPSKCQCLGGEANS-RALCVDAALEDVPIQLNPETKYINLTVNRIRTLEFS---LPFYMKLEILDLSQNIIETLGSKNFEYQSELRTLNLSRNLVSSLHKHAFKGLTNLLLLDLSFNRIETVHPTALSDLASLVELDLTNNNIVSLEDNCFKGMNTLEVLVFRNNRLLDVPASNLWHLHALKSLDMSLNLVEFVRNDS---------------FEGLKELLALSV--QGNVMSELDLSAFEGLIS----LKHLDLSDNNLTMVPTQQLSKLSNLTYLNLGGNRFSQLPAVAFLNLFHLRELHLSRLDFLQRIDSRAFVDNTHLQTLHLNNNPQLSDIPMRLFQGNPN---------ILEVYMQSNSLQTLYSAQFPVDQLQKLYLGDNPLQCNCS--LLWLWRLVTGNFEGVDPGMEHAAGGAVAALAKEADDEELADEATAVASTDDGVAALAAYIAEQHIVNALHTTEPSAYELATSSSNRNSGILRMDRQQIGCD-IWRDKVRTRRKLLTMSEGEITCPAHIVTVVCAVITCLLVAMIGISVLYYLRFVKR---------RRKLLHERGP--------------MRTSKSIINVHDRILQGHNPGGLGLGMSMTLGGGNHVNGLGMTLNYPHHAQTLQAHHHYHQAMPLQSHGGNGNHEYQQTTLPQLDKLELERYLAAQTIANEYRALKPWELPVKEADDEPEHLYERFDHYEYP--DTHTMSKLKQAASLNHSNSSAGPSPVPPSSGKPHVVYVXRGRGTGERVSQINTDIEMVGLNHLHLHHHHHNNNNNYRGCVQSAKASGQF---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "X2J6K6-1", "uniprot_id": "X2J6K6_DROME", "id": "X2J6K6-1", "name": "", "aln": "------------------MLFKWLLFSLCIMPAMFSNTKRKCPTECQCSMDDLDRYQAICTKGGLNSLLSPNELDVDVKVIIIRGPRNSITIGPALRQFMKLEILRITDSNLPAIGAESFWGLKYLRILDLSKNNITNITENNFRGQDNLLELDLSKNKVLRMASSTFRHLTDLRRLNLADNSIVELVQRNFFMLSRLKYLDLSGNPLQDLQPDVFRDVPELKVLKCRNCQLKKINPQM---------------YNLLPLLSELDLG--RNEFKFLDKDEFRDVKR----LTKVLLDGNQLSVVVDQLFRMQKSLNHLDLSYNRLAKVPNDSFLQLTNLTFLDLSYNKLVR------------------LEPQSIRSLSNLLTLNISG---------NVLMDLREMRETFEPLIYYFFLTCSKLFFQLIPQLT-------HLAIADMGTMP-------------VGLLHPFKQLRYLNISGNSLNNTALEVIDPCR---------ELEFLDLSRNQLHGISEDTVLRIQGIRNVRLDNNPLICDECHMGKLINVVRQLQWKWDTYPICFLPKSLRGAEINNLDINGLHTCLTFITDEEQNAASTSYNFLEHGGLNTLAILGGIIFVLIAVIILSLVACFSKNRARYYTREDHLNGSESKCLEKNLEATTITTLGNGSSPTTTTTLTLATSPAAPNGPKTNGQGLSLSPANGSTPVHGISDDKGK----EINFTFPVDDRVCTIDELMPSPPPPPQQHPHPNMGSLMYSVSHSPNSATTLAAVAAAATVIPPGAPSHSSMPTPTPTPAEAVVVVLPPPPLPPQQHHHQMDGSLASLREVQQQLVHLSSTLEPLVSVN----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VS84-1", "uniprot_id": "Q9VS84_DROME", "id": "Q9VS84-1", "name": "", "aln": "---------------MTSLVYTVFHLASLQCSVRPEISPCTCETGKAWNHVELSCEKLESFNAVVDSLANKLNADTNIDLKITHSQLDDLEMRSFTDMNFNLYKLRMQWNSLKSLPEVPFRGLSNVTYLSIGDNDLDEIPKHALSHMPSLLTLDIGRCKIRAVQQEDFRGIQRVTNLILVSNIITRLDRGSFP--KSLLILHLGRNQLESLNG-SLHDLHNLESLFINANNITSLDDELPDGGQLRLLMAHNNRLERLPANMAGMHSLETVHIHCNQLRSFDRVLRNAVNLSEVMADNNELEYLAQDEFASCSKVETLQMGCNHIKSLNS-SLLPILKLKNANFSFNDIEEFSMAELHG----------LRSLKTLQLSSNRIQRLLPDPRGVQELMLVNLDLDNNRIDSLNGALAGLGNLRILNLAGNRLEHLQVGDFDGMIRLDILDLTG-----NQLAELKPLEMTLLPSLKILKVAYNNITKLEQDFKGLPVLCQAN---LTNNQISTISSELVTNTRCKNHNVPGKLEIHLDDN-PIMCDVGLNELCRLMAVQEARIRGRSQCFENDQEVCTVLPMLYNVNLPIMVTNLKLTGREVPKPMVRVIVPSLIKANN-----ELLPPLIATLGNPVLISTDLVNPVISPLPPPLLLATTTPPPPLPLPVESEVEKNESTTANPVPTNYTQETTTTTSTTTTTTTTETSSQVAPIEIITTTAPTTTTTSTTTPKPNETLPVIVELQDPNPPDTTVNQTALVPPVVLDPLQQDLERERERERERELERDLDHEAVAKTEYETVEYIPNLVQPPVGSDALTPPPSKANALEEDSESVHSNSVHAEYPHAAQSLQIPEEPPEE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . :..: .. . : :: * : *.: : : :. : * * : : : : : * : .. * : * * : . : .: *: * : : : : . : * : : .. : . : . : : . . .: : : . * : : : : . . * : . . . : : . : . * . : . . :. : .. ", "identical_positions": 14, "similar_positions": 83, "identity": "1.63%" }, { "cls_id": "homologset.agr.RGD:1308171", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M5J2-1", "uniprot_id": "A0ABK0M5J2_RAT", "id": "A0ABK0M5J2-1", "name": "Mimecan", "aln": "MESAVEFHMGVKLLGPETLFSSLKQFHSFAHSLSHLGLMHRKTQGLQPDTTVPWEDFDCTQYLYSRLWAFNKLASSFKIVDGEKRGLFHSHQVSNFLTSSHLVFAAMKTVHPTLLLLLFVPLTQQTPQTQLDSHVNSKYGTDNSEETKFIQDYEDKYLDGKNIKEKETMIIPDEKSLQLQKDEVIPSVPTKKENDEMPTCLLCVCLSGSVYCEEV--DIDAVPPLPKESAYLYARFNKIKKLTAKDFADMPNLRRLDFTGNLIEDIEDGTFSKLSLLEELTLAENQLLRLPVLPPKLTLLNAKYNKIKSKGIKANTFKKLNKLSFLYLDHNDLESVPPNLPESLRVIHLQFNSISSITDDTFCKANDTRYIRERMEEIRLEGNPIALGKHLRQMLQNLCTAKCSQ-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62000-1", "uniprot_id": "MIME_MOUSE", "id": "Q62000-1", "name": "Mimecan", "aln": "----------------------------------------------------------------------------------------------------------METVHSTFLLLLFVPLTQQAPQSQLDSHVNYEYATGNSEETKFSQDYEDKYLDGKSIKEKETMIIPDEKSLQLQKDEVIPSLPTKKENDEMPTCLLCVCLSGSVYCEEV--DIDAVPPLPKESAYLYARFNKIKKLTAKDFADMPNLRRLDFTGNLIEDIEDGTFSKLSLLEELTLAENQLLRLPVLPPKLTLLNAKHNKIKSKGIKANTFKKLNKLSFLYLDHNDLESVPPNLPESLRVIHLQFNSISSLTDDTFCKANDTRYIRERIEEIRLEGNPIALGKHPNSFICLKRLPIGSYF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P20774-1", "uniprot_id": "MIME_HUMAN", "id": "P20774-1", "name": "Mimecan", "aln": "----------------------------------------------------------------------------------------------------------MKTLQSTLLLLLLVPLIKPAPPTQQDSRIIYDYGTDNFEESIFSQDYEDKYLDGKNIKEKETVIIPNEKSLQLQKDEAITPLPPKKENDEMPTCLLCVCLSGSVYCEEV--DIDAVPPLPKESAYLYARFNKIKKLTAKDFADIPNLRRLDFTGNLIEDIEDGTFSKLSLLEELSLAENQLLKLPVLPPKLTLFNAKYNKIKSRGIKANAFKKLNNLTFLYLDHNALESVPLNLPESLRVIHLQFNNIASITDDTFCKANDTSYIRDRIEEIRLEGNPIVLGKHPNSFICLKRLPIGSYF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TCN2-1", "uniprot_id": "A0AB32TCN2_DANRE", "id": "A0AB32TCN2-1", "name": "Mimecan", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------MEVK--KSKKKVILSQDYDNPADKDVEIPGADPK-DDEDLPTCLMCVCLTGSVYCEDVSPDMTTVPALPQETAYLYACFNKITKITNKDFANIATLKRIDLSGNLISEIEDGAFSKLSHLEELTLAGNKLVKLPMLPANLLSLDVNHNLLKTKGVKANIFKKLIKLAYLYLGDNGLEAIPP-LPESLRVVHLHNNNITSLTDDTFCKGNSTHYIRHNMQEVRLDGNPITLAQHPNSFICLRALPIGHYK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: * *.*:.:*:.:: . :** *. .* :::::****:****:******:* *: :**.**:*:***** ****.*:* ****::..*:*:*::****.:****:***** ****:** *:*::**:**.:* ::.::* :*::*:*** **** :*::***..* **::* *******:**: *.*:*:*******.*.* ***..::*:**:****.*.:* ..:: . ", "identical_positions": 124, "similar_positions": 84, "identity": "30.54%" }, { "cls_id": "homologset.agr.RGD:1308172", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q68FV8-1", "uniprot_id": "UBTD1_RAT", "id": "Q68FV8-1", "name": "Ubiquitin domain-containing protein 1", "aln": "MGNCVGRQRRE------------RPAAPGHPRKRAGRNEPLKKERLKWKSDYPMTDGQLRSKRDEFWDTAPAFEGRKEIWDALKAAAYAAEANDHELAQAILDGASITLPHGTLCECYDELGNRYQLPIYCLSPPVNLLLEHTEEESLEPPEPTPSVRREFPLKVRLS-TGKDVRLSASLPDTVGQLKRQLHSQEGIEPSWQRWFFSGKLLTDRTRLQETKIQKDFVIQVIINQPPPPQD---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91WB7-1", "uniprot_id": "UBTD1_MOUSE", "id": "Q91WB7-1", "name": "Ubiquitin domain-containing protein 1", "aln": "MGNCVGRQRRE------------RPAAPGHPRKRAGRNEPLKKERLKWKSDYPMTDGQLRSKRDEFWDTAPAFEGRKEIWDALKAAAYAAEANDHELAQAILDGASITLPHGTLCECYDELGNRYQLPIYCLSPPVNLLLEHTEEESLEPPEPTPSVRREFPLKVRLS-TGKDVRLNASLPDTVGQLKRQLHSQEGIEPSWQRWFFSGKLLTDRTRLQETKIQKDFVIQVIINQPPPPQD---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HAC8-1", "uniprot_id": "UBTD1_HUMAN", "id": "Q9HAC8-1", "name": "Ubiquitin domain-containing protein 1", "aln": "MGNCVGRQRRE------------RPAAPGHPRKRAGRNEPLKKERLKWKSDYPMTDGQLRSKRDEFWDTAPAFEGRKEIWDALKAAAYAAEANDHELAQAILDGASITLPHGTLCECYDELGNRYQLPIYCLSPPVNLLLEHTEEESLEPPEPPPSVRREFPLKVRLS-TGKDVRLSASLPDTVGQLKRQLHAQEGIEPSWQRWFFSGKLLTDRTRLQETKIQKDFVIQVIINQPPPPQD---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q4V8W7-1", "uniprot_id": "UBTD1_DANRE", "id": "Q4V8W7-1", "name": "Ubiquitin domain-containing protein 1", "aln": "MGGCVGRERAET-----------RGRGSRTQRKRGGRNEPLKKDKPKWKSDYPMTEGQLRSKRDEFWDTAPAFEGRKEIWDALKAAAVALECSDHELAQAIVDGANITLPHGSLTECYDELGNRYQLPVYCLAPPVNLISERSEEDLTDNPEPQTAQKKEFQLKVRLS-TGKDLRLNASMSDTIGLLKKQLQAQEDIDISHQRWFFSGKLLTDKTRLQDTKIQKDFVIQVIVNQPAPNH----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VNB2-1", "uniprot_id": "Q9VNB2_DROME", "id": "Q9VNB2-1", "name": "Ubiquitin-like domain-containing protein", "aln": "MGACVCRMNPDNETMSVSSASISRPASAGIAMGAARKNRPLCHETIRWRSDVPLTEGQLRSKRDEFWDTAPAFDGRKEIWDALRAATTAAEGLDFQMAQAILDGANVSVPNGYLTECYDELGTQYKVPIYCLSYPINIVKEENGRDSPAEYSEPVDGGTDIFLKLRISSTMTDVKLPVYSKDTVGQCKKKLQAAEGVDACCQRWFYSGKLLGDKVPIDECSIHQGYVVQVIVNTEHYNHDNSTSTAHAS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** ** * . : * .. . :*.** :: :*:** *:*:*****************:*********:**: * * *.::****:***.:::*:* * *******.:*::*:***: *:*:: *.. .: . :: **:*:* * .*::* . **:* *::*:: *.:: . ****:***** *:. ::: .*::.:*:***:* : ", "identical_positions": 99, "similar_positions": 70, "identity": "39.76%" }, { "cls_id": "homologset.agr.RGD:1308173", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6ANN9-1", "uniprot_id": "A0A8I6ANN9_RAT", "id": "A0A8I6ANN9-1", "name": "Doublesex- and mab-3-related transcription factor A2", "aln": "MELRSELPSVPGAAT-AAATATGPPVASVASVAAAAAAAASLPVSVAGGLLRAPPLLLRAAEKYPRTPKCARCRNHGVVSALKGHKRYCRWKDCLCAKCTLIAERQRVMAAQVALRRQQAQEENEARELQLLYGTAEGLALAAANGIIPPRPAYEVFGSVCATDGGGPGAGAPAGSAGGAGGAGGAEAKLQKFDLFPKTLLQAGRPDSPQPPPGKPLSPDGADSGPGTSSPEVRPGSGSENGDGESFSGSPLARASKEAGGSCPGSAGASGGGEEDSPGSSSPLGSESGSEADKEEAEAAPTPGLGGGPGPRQRTPLDILTRVFPGHRR-GVLELVLQGCGGDVVQAIEQVLNHHRGGLAAGLGPAAPLEKAAVSAAAAVEDAWPGRVEAAAA-----GGAGLPAPLQTGPAAPPHHRPLLAGAMTPGALGSLSSRSAFSPLQPNASHFGADAGAYPLGAPLGLSPLRLAYSAAAAHSRGLAFMAPYSTAGLVPTLGFRPPMDYAFSDLMRDRSA---------AAAAAVHKEPGYGGGLYGPMVNGTPEKQ-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2A9A2-1", "uniprot_id": "DMTA2_MOUSE", "id": "A2A9A2-1", "name": "Doublesex- and mab-3-related transcription factor A2", "aln": "MELRSELPSVPGAAT-AAATATGPPVASVASVAAAAAAAASLPVSVAGGLLRAPPLLLRAAEKYPRTPKCARCRNHGVVSALKGHKRYCRWKDCLCAKCTLIAERQRVMAAQVALRRQQAQEENEARELQLLYGTAEGLALAAANGIIPPRPAYEVFGSVCATDGGGPGAGAPAGSAGGAG---GAEAKLQKFDLFPKTLLQAGRPDSPQPPPGKPLSPDGADSGPRTSSPEVRPGSGSENGDGESFSGSPLARASKEAGGSCPGSAGAGGGGEEDSPGSSSPLGSESGSEADKEEAEAAPTPGLGGGPGPRQRTPLDILTRVFPGHRR-GVLELVLQGCGGDVVQAIEQVLNHHRGGLAAGLGPAAPLEKAAVS--AAVEDAWPGRVEAAAA-----GGAGLPAPLQTGPTAPPHHRPLLAGAMTPGALGSLSSRSAFSPLQPNASHFGADAGAYPLGAPLGLSPLRLAYSAAAAHSRGLAFMAPYSTAGLVPTLGFRPPMDYAFSDLMRDRSA---------AAAAAVHKEPGYGGGLYGPMVNGTPEKQ-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96SC8-1", "uniprot_id": "DMTA2_HUMAN", "id": "Q96SC8-1", "name": "Doublesex- and mab-3-related transcription factor A2", "aln": "MELRSELPSVPGAATAAAATATGPPVASVASVAAAAAAAASLPVSVAGGLLRGPPLLLRAAEKYPRTPKCARCRNHGVVSALKGHKRYCRWKDCLCAKCTLIAERQRVMAAQVALRRQQAQEENEARELQLLYGTAEGLALAAANGIIPPRPAYEVFGSVCAADGGGPGAGAPAGTGGGAAGAGGSEAKLQKFDLFPKTLLQAGRPGSPLPPPVKPLSPDGADSGPGTSSPEVRPGSGSENGDGESFSGSPLARASKEAGGSCPGSAGPGGGGEEDSPGSASPLGSESGSEADKEEGEAAPAPGLGGGSGPRQRTPLDILTRVFPGHRR-GVLELVLQGCGGDVVQAIEQVLNHHRGGLAAGLGPAAPPDKAAVGAAAAADDAWPSRVDAAAAAAAAAGGPGLPAPLQAGPAAPPHHRPLLAGAMAPGALGSLSSRSAFSPLQPNASHFGADAGAYPLGAPLGLSPLRLAYSAAAAHSRGLAFMAPYSTAGLVPTLGFRPPMDYAFSDLMRDRSA---------AAAAAVHKEPTYGGGLYGPMVNGAPEKQ-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5UU75-1", "uniprot_id": "DMTA2_DANRE", "id": "Q5UU75-1", "name": "Doublesex- and mab-3-related transcription factor A2", "aln": "MDLRPEIPPASQAGS---QVHPG--------AAAAAAAAASIPVSMAGSLLRAPPLLLRATEKYPRTPKCARCRNHGVVSALKGHKRYCRWKDCMCAKCTLIAERQRVMAAQVALRRQQAQEENEARELQLLYGTAEGLALAAANGIIPPRQNYEVFGPVSNESNSG-------------------ESNIQKFELFPKTPLPG--TVTPHQAAGKSVSTD-TESVPGMSSPDMRHGSGSENGDRESIVSSPIAKPLKDG---------------EETPGSISPIGSDSGSDTDKDEQEPSPSS-----AASRQMNAIDILTRVFPNHKR-SVLELVLQGCGKNVVQAIEQILNNS--GQAKGP-----------------EETWTAERMLQSV----------------QPTMSSTPRPMLPGTMT------LSNRSAFSPLQPNAPHFGSDPSTYPLSTHLGLNPLRLAYS---AHSRGLAFMAPYSTTGLMPTLGFRPPMDYAFSDLIRDR--------------TLLHKDQSYTNGLYGPLVNNTQEKQ-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VAI8-1", "uniprot_id": "Q9VAI8_DROME", "id": "Q9VAI8-1", "name": "", "aln": "-----------------------------MSLPSGVDMQNLMSQHPVLGALPPAFFLRAASERYQRTPKCARCRNHGVVSALKGHKRYCRWRDCVCAKCTLIAERQRVMAAQVALRRQQAQEENEARELGLLYTSVPGQQNGSDS-ATPTPHSPNHSGSGGSGSGGSGQNGVFHGGIPSPPSDGFEASSTPNHHQQSQQQQQAHHQQHLSHPHQQSQRFNGNESDTDGRTRSEHLSVGFSPTRTELDESPVSKRGAALSNETDQDTGSESGSPSSPRPKVAGLFNLTASLSPARTGPPSSPESDLDVDSAPDEATPENLSLKKEDSQSPPNTPAENLHLLRSFSSSHAQGFLPYHHTQFLAAAGLPAHHHPAAHSPHHQQQQQQQQQQQNHLP------------QHHQQQQQQQQQQQRSPIDVLMRVFPNRRRSDVEQLMQRFRGDVLQAMECMLAGEDLGQTPPQVPPSPPFPMKSAFSPLVPPSVFG-SPTHRYHPFMQAHAKRFLTAPYAGTGYLPGVLSAADIEQSESNGAGGIGLDRTSNAGDSQD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:.. :. . . * . :* *:*:* **************************:**:********************************** *** :. * .: . *. : *. .... :. :.. .: . . :. : :* . : . : . * . * .. : . . * . :. :. .. : .:* . ... : .. :: : .: .. *: . : .* . :: . : . : .. . :* .. . ** .* ::. * . . .:: :.* *. * ** ::* *: . :: :.: .*: ...: :.* ", "identical_positions": 94, "similar_positions": 121, "identity": "17.0%" }, { "cls_id": "homologset.agr.RGD:1308174", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZYS4-1", "uniprot_id": "D3ZYS4_RAT", "id": "D3ZYS4-1", "name": "Fidgetin", "aln": "-----------MQWTPEHAQWPEQHFDITSTTRSPAHKVEAYRGHLQRTYQYAWANDDISALTASNLLKKYAEKYSG-------ILEGPVDRPVLSNYSDTPSGLVNGRKNDSEPWQSSLNSEAVYPMNCVPDVITAS-------------------------------------------------------------------------------------------------------------KAGVSSALPPVDVSASIGSSPGVASNLTEPSYSSSTCGSHTVPSLHAGLPSQEYAPGYNGSYLHSTYSS-QPTPALPSPHPSPLHSSGLLQPP-PPPPPPPALVPGYNGTS-NLSSYSYPSASYPPQTAVGSGYSPGGAPPPPSAYLPSGIPAPTPLPPTTVPGYTYQGHGLTPIAPS-ALTNSSASSLKRKAFYMAGQGDMDSSYGNYSYGQQRSTQSPMYRMPDNSISNSNRGNGFDRNAETSSLAFKPTKQLMPSEQQRKFSSQSSRALTPPSYSTAKNSLGS-RSSESFGKYTSPVMSEHGDDHRQLLAHPIQGPGLRAATSSNHSVDEQLKNTDTHLIDLVTNEIITQGPPVDWSDIAGLDLVKAVIKEEVLWPVLRSDAFSGLTALPRSILLFGPRGTGKTLLGRCIASQLGATFFKIAGSGLVAKWLGEAEKIIHASFLVARCRQPSVIFVSDIDMLLSSQVSEEHSPVSR-MRTEFLMQLDTVLTSAE------------------DQIVVICATSKPEEIDESLRRYFMKRLLIPLPDSTARHQIIVQLLSQHNYCLNDKEFALLVQRTEGFSGLDVAHLCQEAAVGPLHAMPATDLSAIMPSQLRPITYQDFENAFCKIQPSISQKELDMYVEWNKMFGCSQ-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ERZ6-1", "uniprot_id": "FIGN_MOUSE", "id": "Q9ERZ6-1", "name": "Fidgetin", "aln": "MISSTSVYGLKMQWTPEHAQWPEQHFDITSTTRSPAHKVEAYRGHLQRTYQYAWANDDISALTASNLLKKYAEKYSG-------ILEGPVDRPVLSNYSDTPSGLVNGRKNDSEPWQPSLNSEAVYPMNCVPDVITAS-------------------------------------------------------------------------------------------------------------KAGVSSALPPVDVSASIGSSPGVASNLTEPSYSSSTCGSHTVPSLHAGLPSQEYAPGYNGSYLHSTYSS-QATPALPSPHPSPLHSSGLLQPP-PPPPPPPALVPGYNGTS-NLSSYSYPSASYPPQTAVGSGYSPGGAPPPPSAYLPSGIPAPTPLPPTTVPGYTYQGHGLTPIAPS-ALTNNSASSLKRKAFYMAGQGDMDSSYGNYSYGQQRSTQSPMYRMPDNSISNSNRGNGFDRNAETSSLAFKPTKQLMPSEQQRKFSSQSSRALTPPSYSTAKNSLGS-RSSESFGKYTSPVMSEHGDDHRQLLAHPIQGPGLRAATSSNHSVDEQLKNTDTHLIDLVTNEIITQGPPVDWSDIAGLDLVKAVIKEEVLWPVLRSDAFSGLTALPRSILLFGPRGTGKTLLGRCIASQLGATFFKIAGSGLVAKWIGEAEKIIHASFLVARCRQPSVIFVSDIDMLLSSQVSEEHSPVSR-MRTEFLMQLDTVLTSAE------------------DQIVVICATSKPEEIDESLRRYFMKRLLIPLPDSTARHQIIVQLLTQHNYCLNDKEFALLVQRTEGFSGLDVAHLCQEAAVGPLHAMPATDLSAIMPSQLRPVTYQDFENAFCKIQPSISQKELDMYVEWNKMFGCSQ-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5HY92-1", "uniprot_id": "FIGN_HUMAN", "id": "Q5HY92-1", "name": "Fidgetin", "aln": "MISSTSVYGLKMQWTPEHAQWPEQHFDITSTTRSPAHKVEAYRGHLQRTYQYAWANDDISALTASNLLKKYAEKYSG-------ILEGPVDRPVLSNYSDTPSGLVNGRKNESEPWQPSLNSEAVYPMNCVPDVITAS-------------------------------------------------------------------------------------------------------------KAGVSSALPPADVSASIGSSPGVASNLTEPSYSSSTCGSHTVPSLHAGLPSQEYAPGYNGSYLHSTYSS-QPAPALPSPHPSPLHSSGLLQPP-PPPPPPPALVPGYNGTS-NLSSYSYPSASYPPQTAVGSGYSPGGAPPPPSAYLPSGIPAPTPLPPTTVPGYTYQGHGLTPIAPS-ALTNSSASSLKRKAFYMAGQGDMDSSYGNYSYGQQRSTQSPMYRMPDNSISNTNRGNGFDRSAETSSLAFKPTKQLMSSEQQRKFSSQSSRALTPPSYSTAKNSLGS-RSSESFGKYTSPVMSEHGDEHRQLLSHPMQGPGLRAATSSNHSVDEQLKNTDTHLIDLVTNEIITQGPPVDWNDIAGLDLVKAVIKEEVLWPVLRSDAFSGLTALPRSILLFGPRGTGKTLLGRCIASQLGATFFKIAGSGLVAKWLGEAEKIIHASFLVARCRQPSVIFVSDIDMLLSSQVNEEHSPVSR-MRTEFLMQLDTVLTSAE------------------DQIVVICATSKPEEIDESLRRYFMKRLLIPLPDSTARHQIIVQLLSQHNYCLNDKEFALLVQRTEGFSGLDVAHLCQEAVVGPLHAMPATDLSAIMPSQLRPVTYQDFENAFCKIQPSISQKELDMYVEWNKMFGCSQ-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q503S1-1", "uniprot_id": "FIGN_DANRE", "id": "Q503S1-1", "name": "Fidgetin", "aln": "-----------MQWTPEHAQWAEQHFDISSTTRSLAHKAEAYRGHLQRTYQYAWANDDISALTASNLLKKYAEKYSG-------ILEGPSERALLCSYSESAPGLLNGRKSESDAWQ-----EGIYPMSCAADVISAS-------------------------------------------------------------------------------------------------------------KTGMTPALPPPDVTASVGSSTGVASSLSEPSYSSSNCGNHAS-ALHSGIPSQEFASSYNGSYLHSTYSGGQSTPALPSPHPSPLHSAGLLQPP-PPPPP--TLVPSYNTSSPNLSSYNYPPAGYPPQTPVAPGYSPGGAPPP-SAYLPSGIAAPTPLPPSTIPGYSYQSHNHAPIAPT-PLNGSSANTLKRKAFYMTGQGDMDSSYGNFNYSQQRSAQSPMYRMPDNSLVDSTRGNGFDRNADTSSLAFKPTKQSMPTDQQRKFGSQAGRALTPPSYGSSKGSLGSMRSGESFGKFGSPVMSDHGDDSRQHLPHSID-----TATSSSHPAEEQLKNSDANLVEMVTTEILQQTSPVDWSDIAGLEMAKATIKDEVLWPILRPDMFSGLATLPRSILLFGPQGTGRTLLGRCMASQLGAAFLLLSGSALVTKWLGEGEKIVQASFLIARCRQPSVVFISDVDLLLSSQLSEE-SPVNR-IKSELLLQLDGVLSSPE------------------EHVLVVCSTSKPEEIDESLRRYFVKRLLVPLPDATARHQIISQLLSQHNYCLSDKEVTLLVQRTDGFSGLDVVRLCQEALVGPLHGMPGADLSGMIPGQMRPVSYQDFENVFCKIQPSISQKELDTYTEWNKMFGCSQ-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P39955-1", "uniprot_id": "SAPR1_YEAST", "id": "P39955-1", "name": "Microtubule severing ATPase SAP1", "aln": "--MDSQRSHHILTRLTKIRRRPQQPLTDFTELYSRIANETIYYLNLEEKKRYKEALQGWKALTTDVLFKQTLIEHNYPNTQSYTKDEVSLQNGIRELYHKSVMHLKRVKKLVREEPAPRNDMPSSKTYTNHSSSFTRSTEPPPVFQMVPGRMMKTLRNRNACGYKTAYSNPSLSSYGNSTSIKRGEDAENIRVNFVPSKPLSNNASRQHKNPIEHNDPPLKKETELYSDKYISEPILIDLTNDEDDHDVGILKGHNVFDEEESDGFEFDVSDYYDNFSEVDVEEEEEEKEERRRIKTLEAIQQQMSDLSVTSSTSSNKSVSSSENVPGSCIQSLPTTAPALPSLPPPPLLNVDRASSTGALKPHSLETSTTMDSSKIRNPQISKLMKNNHVPYLKGTKSTPTLITKSTPTFITRSKSNTKPIIKSNASSPTSSLTVPNSVIQKPKTAAMAAKRVLNSKKVASNPALNTTKKSHPILKSKTAKVPNSSSKKTSSHPSRPVSNSKPYSHGASQNKKPSKNQTTSMSKTNRKIPAQKKIGSPKIEDVGTEDATEHATSLNEQREEPEIDKKVLREILEDEIIDSLQGVDRQAAKQIFAEIVVHGDEVHWDDIAGLESAKYSLKEAVVYPFLRPDLFRGLREPVRGMLLFGPPGTGKTMLARAVATESHSTFFSISASSLTSKYLGESEKLVRALFAIAKKLSPSIIFVDEIDSIMGSRNNENENESSRRIKNEFLVQWSSLSSAAAGSNKSNTNNSDTNGDEDDTRVLVLAATNLPWSIDEAARRRFVRRQYIPLPEDQTRHVQFKKLLSHQKHTLTESDFDELVKITEGYSGSDITSLAKDAAMGPLRDLG-DKLLETEREMIRPIGLVDFKNSLVYIKPSVSQDGLVKYEKWASQFGSSGS", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VQN8-1", "uniprot_id": "FIGL1_DROME", "id": "Q9VQN8-1", "name": "Fidgetin-like protein 1", "aln": "---MSDEQSSWRSKLLLICQQTRS------------SSESIHFAALKDHHARLQACE-------------------------------SMEKAMKERCQKKITMSRRTKR-------------------------------------------------------------------------------------------------------------------------------------------GITHAGYLFEMPHNSVFEPECRGFYESCQQTEMASS----------------DLQAPALEVSSTYPVQQAVKSR----------------------PEGQFPESRNNSTKKIDAQQYSSESSSQSG---------------------------------FGFRTAREQLIMDELKKKNRQATSEVDAVPTGMMNFRKKTLGGKRTVSSN-----------------FVSPVAQNDNSTSSRSSSIPP------------------------------------------------------------------------------------ALAHLDSKMVDHILGESMHDFKPVAWEDIAGLESAKSTFLEAIIMPLRRPDLFTGVRCPPRGVLLFGPPGTGKTLIAKSIASQAKAKFFSINPSSLTSKWVGDAEKLVKTLFAVAAAHQPAIIFIDEVDSLLSKRS-ANENESTLRLKNEFLIHLDGAASNEE------------------IRVLVIGATNRPQELDEAVRRRFVRRLYVPLPTREARQKIIEKLIHQVKHNLDVRQVIELAELTDGYSGADVDTLCRYASMAPLRSLTPDQMEVIETHQLPAVTMDDFKQALRVISKSVSSEDCKQFEAWNEIYGVRH-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ... . : *: * : . :. : .. . :: *: . : . . . . . . : *: . :.. : * : . :: :.. . . . : . .* . : : .. . : . . . :** . * * : . : * : . * *.*****: .* : : :: *. *.* * *: *.:***** ***:*::.:.:*:: : *: : *.*.:*::*:.**:::: * :* .*:::*:.::* ::..: : . . ::.*:*:: . : :::*: :*. * .:**: ** *::* :*** :*: : :*: : :: * :. *.: *:*:** *: *.: * :.**: : .: : .: **:: : *. *:*.. : * . :* ", "identical_positions": 81, "similar_positions": 171, "identity": "9.0%" }, { "cls_id": "homologset.agr.RGD:1308176", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P30276-1", "uniprot_id": "CCNB2_MOUSE", "id": "P30276-1", "name": "G2/mitotic-specific cyclin-B2", "aln": "----------MALLRRPTVSSDLKNIDTEVIPKAKSHVTIRRAVLEEIGNKVRNRTTQVAKKPQN-------------------------------------------------------------TKVPALPTKVTNVNKQ-------------------------------------------------------------PKPTASVKPVQMEALAPKD---------RPPAPEDVSMKEES--------------------LCQAFSDALLCKIEDIDNEDRENPQLCSDYVKDIYQYLRQLE-VLQSINPHFLDGRD---INGRMRAILVDWLVQVHSKFRLLQETLYMCIAIMDRFLQAQLVCRKK-LQLVGITALLLASKYEEMFSPNIEDFVYITDNAYTSSQIREMETLILKELKFELGRPLPLHFLRRASKAGEVDVEQHTLAKYLMELTLVDYDMVHYHPSQVAAAASCLSQKVLG----------QGKWNLKQQYYTG-YMESEVLEVMQHMAKNVVKVNDNRTKFIAVKNKYASSRLLKISTIPQLNSKIIKDLASPLLGSP-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5M857-1", "uniprot_id": "Q5M857_RAT", "id": "Q5M857-1", "name": "", "aln": "----------MALLRRPTVSSDLKNIDTGVNPKAKSHVTVRRAVLEEIGNKVRARPAQVAKKPQN-------------------------------------------------------------TKVPVQPTKAINASKQ-------------------------------------------------------------PKPTASVKPVQMETLAPKD---------PLPAPEDVSMKEES--------------------LCQAFSDALLCKIEDIDNEDGENPQLCSDYVKDIYQYLRQLEQALQSINPHFLDGRD---INGRMRAILVDWLVQVHSKFRLLQETLYMCIAIMDRFLQAQPVCRKK-LQLVGITALLLASKYEEMFSPNIEDFVYITDNAYTSSQIREMETLILKELKFELGRPLPLHFLRRASKAGEVDVEQHTLAKYLMELTLVDYDMVHYHPSQVAAAASCLSQKVLG----------QGKWNLKQQYYTG-YMESEILEVMQHMAKNVVKVNENLTKFIAVKNKYASSRLLKISTIPQLNSRTIKDLASPLMGRP-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O95067-1", "uniprot_id": "CCNB2_HUMAN", "id": "O95067-1", "name": "G2/mitotic-specific cyclin-B2", "aln": "----------MALLRRPTVSSDLENIDTGVNSKVKSHVTIRRTVLEEIGNRVTTRAAQVAKKAQN-------------------------------------------------------------TKVPVQPTKTTNVNKQ-------------------------------------------------------------LKPTASVKPVQMEKLAPKG---------PSPTPEDVSMKEEN--------------------LCQAFSDALLCKIEDIDNEDWENPQLCSDYVKDIYQYLRQLE-VLQSINPHFLDGRD---INGRMRAILVDWLVQVHSKFRLLQETLYMCVGIMDRFLQVQPVSRKK-LQLVGITALLLASKYEEMFSPNIEDFVYITDNAYTSSQIREMETLILKELKFELGRPLPLHFLRRASKAGEVDVEQHTLAKYLMELTLIDYDMVHYHPSKVAAAASCLSQKVLG----------QGKWNLKQQYYTG-YTENEVLEVMQHMAKNVVKVNENLTKFIAIKNKYASSKLLKISMIPQLNSKAVKDLASPLIGRS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P20439-1", "uniprot_id": "CCNB_DROME", "id": "P20439-1", "name": "G2/mitotic-specific cyclin-B", "aln": "-----MVGTTLKMRGDENASENFKQVQLKKLTVPSMEATTKRAALGDLQNRGISRPIAAKDAAQKDSKDLKLTDALRNAKARVDSHWKKQPLGSTNGNGNGAVPPKVNEGGVSAFLRSNSVRNRVPTKTTVEPTKVTVKSSSSENVNEPTLKREDS---------------------------------NLSKKSLTKLRAALAKPVMGVSGIRREPVAVSRKEAETKKELPETKKDSLEVKKDATRMPLIRGNSAVTTTTSTMPTTMSLSSKRLAGIEDIDANDKENLVLVSEYVNDIYDYLYQVELEQPIHKDHLAGQKE---VSHKMRAVLIDWINEVHLQFHLAAETFQLAVAIIDRYLQVVKDTKRTYLQLVGVTALFIATKYEELFPPAIGDFVFITDDTYTARQIRQMELQIFKAIDCNLSRPLPIHFLRRYSKAAGAEDEHHTMSKYFIELASVDYEMATYRPSEIAAASLFLSLHLLNGNHRAGTGFNDRHWTPTLTFYSR-YSAAHLRPITRLIAK--LARDAPQAKLKAIYNKYQGSKFQKIALRTELTGALMDSIVGQSQRK--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P24868-1", "uniprot_id": "CG21_YEAST", "id": "P24868-1", "name": "G2/mitotic-specific cyclin-1", "aln": "MSRSLLVENSRTINSNEEKGVNESQYILQKRNVPRTILGNVTNNANILQEISMNRKIGMKNFSK--------------------------------------------------LNNFFPLKDDVSR---ADDFTSSFNDS-RQGVKQEVLNNKEN----IPEYGYSEQEK------------QQCSNDDSFHTN--------STALSCNRLIYSENKSIST--------QMEWQKKIMREDSKKKRPISTLVEQDDQKKFKLHELTTEEEVLEEYEWDDLDEEDCDDPLMVSEEVNDIFDYLHHLEIITLPNKANLYKHKN----IKQNRDILVNWIIKIHNKFGLLPETLYLAINIMDRFLCEEVVQLNR-LQLVGTSCLFIASKYEEIYSPSIKHFAYETDGACSVEDIKEGERFILEKLDFQISFANPMNFLRRISKADDYDIQSRTLAKFLMEISIVDFKFIGILPSLCASAAMFLSRKMLG----------KGTWDGNLIHYSGGYTK----AKLYPVCQLLMDYLVGSTIHDEFLKKYQSRRFLKASIISIEWALKVRKNGYDIMTLHE", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P24869-1", "uniprot_id": "CG22_YEAST", "id": "P24869-1", "name": "G2/mitotic-specific cyclin-2", "aln": "MSN--PIENTENSQNTSSSRFLRNVQRLALNNVTNTTFQKSNANNPALTNFKSTLNSVKKEGSR--------------------------------------------------IPQFT--RESVSRSTAAQEEKRTLKENGIQLPKNNLLDDKENQDPSSQQFGALTSIKEGRAELPANISLQESSSAKEIIQHDPLKGVGSSTEVVHNSVENEKLHPARS--------QLQVRNTESETDSGKKRPISTIVEQELPKKFKVCD----ENGKEEYEWEDLDAEDVNDPFMVSEYVNDIFEYLHQLEVITLPKKEDLYQHRN----IHQNRDILVNWLVKIHNKFGLLPETLYLAINIMDRFLGKELVQLDK-LQLVGTSCLFIASKYEEVYSPSIKHFASETDGACTEDEIKEGEKFILKTLKFNLNYPNPMNFLRRISKADDYDIQSRTLAKFLLEISLVDFRFIGILPSLCAAAAMFMSRKMLG----------KGKWDGNLIHYSGGYTK----EELAPVCHMIMDYLVSPIVHDEFHRKYQSRRFMKASIISVQWALKVRKNGYDIMTLHE", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P32943-1", "uniprot_id": "CGS6_YEAST", "id": "P32943-1", "name": "S-phase entry cyclin-6", "aln": "--------------------MNCIPSPISER------------KIQINNEDCIGKENAFHTIPR------------------------------------------------ESSINLTPHSTNE--------KKVLSEVN--------------------------------------------------------------SNKIDSLQLPRGKLQRDST--------HLEKTRKRQLSNDST----DPIEPKTVKK-IKCH------------QWKNLDSIEMDDPFMVAEYTDSIFSHLYEKEIQMLPTHNYLMDTQSPYHLKSSMRALLIDWLVEVHEKFHCLPETLFLAINLLDRFLSQNVVKLNK-LQLLCITCLFIACKFEEVKLPKITNFAYVTDGAATVEGIRKAELFVLSSLGYNISLPNPLNFIRRISKADNYCIETRNMAKFIMEYSICCNKFIHLKPSYLAAMSMYIARKIKNEN-------SK--WDETFIHYSGGIDIESDPAFKDFISELVEDIAVPDTNLDSLRLKYKKPKHGMVYFKVFDWCKQKR-----------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P30283-1", "uniprot_id": "CGS5_YEAST", "id": "P30283-1", "name": "S-phase entry cyclin-5", "aln": "--------MGENHDHEQSIKRNSMIYNENERQLCNSNLKILQNKRALSKNDSSSKQQVQDSKPRRALT--------------------------------------------DVPVNNNPLSQNKRIVAGSKAAKVRREEN--------------------------------------------------------------IRPIVSAVQKR-QIYNDRT--------AAEQEEEEEEEGEDD----DAASIVNKKRRIDAEG------VSEIVGWQDLDYVEKDDTAMVAEYSAEIFAFLYRRELETLPSHNYLLDKTSKYYLRPSMRTILVDWLVEVHEKFQCYPETLFLSINLMDRFLAKNKVTMNK-LQLLAVTSLFIAAKFEEVNLPKLAEYAYITDGAASKNDIKNAEMFMLTSLEFNIGWPNPLNFLRRISKADDYDPVNRNIGKFILEYAYCCHQFIHLPPSTVSAMAMYIARRMTNRN-------KNELWNGTLQHYSGGIDPIHDEAFQSLCIDLVKDIASSKTHLDSLILKYKKPRYGSVYFQTFKWCTSEMHSNFQNLFNLK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .: . . : . .::* : :: : :: .*: .* . * : : . * :*::*: ::* :* **: :.: ::**:* ***: :.*::* *:**: * : .:. **.: : *:: * :: : ::. . *::*:** *** :.:.*:::* : : ** :: : :: :: . . * . .*: . . ** : ", "identical_positions": 42, "similar_positions": 87, "identity": "7.29%" }, { "cls_id": "homologset.agr.RGD:1308177", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q96JK9-1", "uniprot_id": "MAML3_HUMAN", "id": "Q96JK9-1", "name": "Mastermind-like protein 3", "aln": "-MGDFAAPAAAANGSSICINSSLNSSLGGAGIGVNNTPNSTPAAPSSNHPAAGGCGGSGGPGGGSAAVPKHSTVVERLRQRIEGCRRHHVNCENRYQQAQVEQLELERRDTVSLYQRTLEQRAKKSGAGTGKQQHPSKPQQDAEAASAEQRNHTLIMLQETVKRKLEGARSPLNGDQQNGACDGNFSPTSKRIRKDISAGMEAINNLPSNMPLPSASPLHQLDLKPSLPLQNS--------------GTHTPGLLEDLSKNGRLPEIKLPVNGCSDLEDSFTILQSKDLKQEPLDDPTCIDTSETSLSNQNKLFSDINLNDQEWQELIDELANTVPEDDIQDLFNEDFEEKKEP-EFS-QPATETPLSQESAS--VKSDPSHSP---FAHVSMGSPQARPSSSGPPFSTVSTATS-LPSVASTPAAPNPASSPANCAVQSPQTPNQAHTPGQAPPRPGNGYLLNP-------AAVTVAGSASGP-------VAVP-SSDMSPAEQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLGPPSSPYGAAFTAEKPNSPMMYPQAFNNQNPIVPPMANNLQKTTMNNYLPQNHMNMINQQPNNLGTN---SLNKQHNILTYGNTKPLTHFN--ADLSQRMTPPVANPNKNPLMPYIQQQQQQQQQQQQQQQQQQPPPPQLQAPRAHLSEDQKRLLLMKQKGVMNQPMAYAALPSHGQEQHPVGLPRTTGPMQSSVPPGSGGMVSGASPAGPG---FLGS---QPQAAIMKQMLID---QRAQLIEQQKQQFLREQRQQQQQQQQQ----------------------ILAEQQLQQSHLPRQHLQPQRNPYPVQQVNQFQGSPQDIAAVRSQA-ALQSMRTSRLMAQ----NAGMMGIGPSQNPGTMATAAAQSEMGLAPYSTTPTSQPGMYN-MSTGMTQMLQ-----HPNQSGMSITHNQAQGPRQPASGQGVGMVSGFGQSMLVNSAITQQHPQMKG--PVGQALPRPQAPPRLQSLMGTVQQGAQSWQQRSLQGMPGRTSGELGPFNNGASYPLQAGQP-RLTKQHFPQGLS-QSVVDANTGTVRTLNPAAMGRQMMPSLPGQQGTSQARPMVMSGLSQGVPGMPAFSQPPAQQQIPS----GSFAPSSQSQAYERNAPQDVSYNY---SGDGAGGSFPGLPDGADLVDSIIKGGPGDEWMQELDELFGNP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6ABZ3-1", "uniprot_id": "A0A8I6ABZ3_RAT", "id": "A0A8I6ABZ3-1", "name": "", "aln": "-MGDFAAPAAAANGGSICINSSLSSSLGGAGIGVN-TPNSTPVAPSSNHPAAGGCGGSGGPGGSSAAVPKHSTVVERLRQRIEGCRRHHVNCENRYQQAQVEQLELERRDTVSLYQRTLEQRAKKSGAGTGKQQHPSKAQQDAEAASAEQRNHTLIMLQETVKRKLEGARSPLNGDQQNGACDGSFSPTSKRIRKDLSTGLEAINNLPSNMPLPSASPLHQLDLKPSLPLQNS--------------AVHTPGLLEDLSKNGRLPEIKLPVNGCGDLEDSFAILQNKDLKQEPLDDPACIDTSETSLSNQNKLFSDINLNDQEWQELIDELANTVPEDDIQDLFNEDFEEKKEQ-EFS-QTAMETPLSQESVS--VKSDASHSP---FAHVSLGSPQARPSSSGPPFSTVSTGTS-LPSVANTPVAPNPASSPANCAVQSPQTPTQAHTPGQAPPRPGNGYLLNP-------VSAAVSGSGSGS-------VAVP-SSDMSPAEQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQ------QQQQHSNQTSSWSPLGPPSSPYGTAFASEKPNSPMMYPQAFNNQSTIVPAMANSLQKTTMNNYLPSNHMTMISQQPNNLGTN---SLNKQHNILTYGNTKPLTHFN--ADLSPRMTPPMANPSKTPLMPYIQQPPQPQPPQQQPPQQQPPPPPQLQAPRAHLSEDQKRMLLIKQKGVMNPPMAYAALPAHGQEQHAVGIPRTTGPMQNSVPPGSGGMVSGASPGGLG---FLGS---QPQAAIMKQMLMD---QRAQLMEHQKQQFLREQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQILAEQQLHQSHLPRQHLQQQRTPYPVQQVNQFQGSPQDIAAVRNQAVALQSMRTSRLMAQ----NAGMVGMGPSQNPGTMATAAAQSEIGLAPYSAPPTSQPGMYN-MNTGMTQMLQ-----HPNQSGMGIPHNQPQGPRQPASGQGVGVVSGFGQSMLVNSAFSQQHQQLKG--PVGQALPRPQGPPRLQSVMGTVQQGAQNWQQRSLQGVPGRTSGELGPFNNSASYPLAAGQP-RLTKQHFPQGLS-QPVMDGNPGAVRTLNPAAMGRQMMPPLAGQQGASQGRPLVIPGLSQGVPGMPAFSQPTAQQQIAG----GSFAAGNQGQAYERNPAQDMSYNY---SGEGAGASFPGLPDSTDLVDSIIKSGPGDEWMQELDELFGNP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M2B6W6-1", "uniprot_id": "A0A8M2B6W6_DANRE", "id": "A0A8M2B6W6-1", "name": "", "aln": "MMGDFASPAAVPTGGGICINNSN-----------------------VNLNSAINAANSGSTGGG--NIPKHSTVVERLRQRIEGCRRHHVNCESRYQQAHAEQLELDRRETVSLYQRSLEQRAKKS--NNSKQQ--SKQQEPDSSASAEQRNSTLIALQETVKRKLDSARSPLNGDQ-NGLSDGSYSPTTKRLRKEGCTGMDSLG------SLPPISPLHQMDIKPTLPSGNNSASSNNGTGNGNAGTNHITGRPEDLGKNGGMPDIKL--NGSLDLDDGFSLL--KDLKQEPLDDGAGIESSETSLSNQNKLFSDINLNDQEWQELIDELANTVPEDDMHDLFNEDFEEKKEVSDFTRVTTEQTQLAQDPAPNSVATAPNSAPQPQSGQMPMGSPQVRPSSSGPPFATAASGTPPQQPLQQSPAVGMPSGSPANCVARSPQTPTQAQT--QAS-RPGNGFMMNAGPAVGPVGSTPVAGGGPGSGGTGGGGVPVPPTSELSPAEQLKQMAAQQQQRAKLIQQKHQQQ-----------------------SQAANWSPAGAPTSPYSGPFNPDKPNSPMMYTQAFNPSNTMGPKAP------SINNYLPQNHINMLNQQQQQQQPNNLAAQNSHNKQLSFSNTKPLTHFSGVDHMNQRMTPPMANQAKNPMMPYMQG----NAAQGGGPPQAPGPMP---SQTAHLSEEQKKMMILKQK-MMSQGLPYGPMQPHVQE--VVGLPRQAGGVQP--PHGGPGGVAPAGPNGAGPGGYLPNPQQQQQAAMMKQMMAMEQEKRVQLHLMEQQQKAQLMREQRQQQQQQ---------------------HMLAEQLQQQQHLPRQMTQAQRNPYPLQ---QFQGTSQEMAAR-NQT--LQNMRTARLMQQQQQQNPGMMQMTPVQNAAAMPT---QGDMSMA-YGGQAGAQTGMYQGMNPNMGQMLQQQQQHHPNQASMAMAQRQAGAGGQGMVGGGAG--AGYGQAMLMNPNLSQQQLKSAGVAPGGQPMAKAQVQ-RLQSMMGGGGQ-AWPQQQQNMQAMAGRTSNDMVAFNSNPAYAMQGGQPPRMAKQHFAQAMGGQTMVDP-----RSINPAAMGGPMMPHMAGQPRTNQPRGMVMPGMNQGVPNMAAFGQGPAQGMPGASGGGGPYMPGGQPQGYQRTSNQELAYGYGSQSGAGAGVSF-GLSDGTDLDS-------TEGWMEEF---FPNQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *****:***...*..****.* * :* ....**..**. :*************************.*****:.*****:**:*******:******** ...*** ** *: .:******* *** *********:.********* ** .**.:***:**:**: .:*::::. .**. *****:*:**:** *. * .* ***.*** :*:*** **. **:*.*::* ********** : *::*************************************::************ :*: .: :* *:*:... * : .. :* .::.:****.*********:*.::.*. .: .:*.. *:.*****..:*****.**:* **. *****:::*. :..*:*...*. *.** :*::*******************:***:*** .*::.*** *.*:***. .* .:********.**** ...: * . ::*****.**:.*:.** :: .* : *.::: *::.********. .:. *****:** *.*:***:* : * * * * : *****:**:::::*** :*. :.*..: .* ** **:** :* :* * *. * *: *.* * * :* . * ***:****: :*.** ::** : *:*:****** :**** :*.***** * **.***:* ****:.*::** .*: **.***:*** * *.**: : * **..:*.* *.::.:* *. . :*.***: *...* **** ****:.*.:.:.*. . * * *.* :*:**:**:*. ::**: : * * **.:.:.* ****:** * * **:.:*.:.****.:: .**...:*.: .*** *::****.*.:. *.::* *::****** *** :.** :.* * :*:.*:.****.*.**.* .** . *.: ...* *.*:*.. *:::*.* ** *** ** **.*.:** . : **:*: * * ", "identical_positions": 556, "similar_positions": 316, "identity": "45.06%" }, { "cls_id": "homologset.agr.RGD:1308178", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A6E1-1", "uniprot_id": "A0A8I6A6E1_RAT", "id": "A0A8I6A6E1-1", "name": "", "aln": "--MASVPAEA-----------------ETRQRLLRTVKKEVKQIMEEAVTRKFVHEDSSHIISFCAAVEACVLHGLRRRAAGFLRSNKIAALFMKVGKGFPPAEELSRKVQELEQLIES---ARNQIQGLQENVRKLPKLPN-------------------------------LSPLAIKHLWIRTALFERVLDKIVHYLVENSSKYYEKEALLMDPVDGPILASLLVGPCALEYTKMKTADHFWTDPSADELVQRHRIHSSHLRQDSPTKRPALCIQKRHSSGSMDDRPS---------ISARDYVESLHQNSRATLLYGKNNVLVQPRDDMEAVPGYLSLHQTADVMTLKWTPNQLMNGSVG---DLDYEKSVYWDYAVTIRLEEIVYLHCHQQ--VDSGGTVVLVSQDGIQRPPFRFPKGGHLLQFLSCLENGLLPHGQLDPPLWSQRGKGKVFPKLR--KRSPQGSSESTSSDKEDDEATDYVFRIIYPGTQSEFVTLDLLGSPRPMSVGPAWMMLAAGHSVLVVARGLQWAQTRGCQTVPTRSVKEQPPMPQDLMDVSMNNLPSLWQPSPRKSSCSSCSQSGSADGSSTNGCNHERAPLKLLCDNMKYQILSRAFYGWLAYCRHLSTVRTHLSALVNHMIVSPDLPCDAGQGLTASIWEQYIQDSTTYPEQELLRLIYYGGVQPEIRRAVWPFLLGHYQFGMTEMERKEVDEQIHACYAQTMSEWLGCEAIVRQRERESHAAALAKCS--------SGASLDSHLHRMLHRDSTISNESSQ-----------SCSSGRQ-NLRLQSDSSSST---------------------QVFESVDEVEQTEAEGRSEE--KHPKIPNGNPANGTCSPDSGHPSSHNFSSG-------LSEHS---EPSLS-----------------------------------------------------------TEDS--VLDVQRSLPAVFRPGDS------------SVEDGQSSE--------------ATTSRDEAPRE---------------------------------ELAVQDSLESDLLAN--------------------------------------------------------------------------------------ESLEEFMSIPGSLDVALPEK-----------------DGAMMDGWPG-EADKHGRADSEDNLSEEPEMESLFPALASLAVTSSANNETSPVSSSGVTYSPELLDLYTVNLHRIEKDVQRCDRSYWYFTAANLEKLRNIMCSYIWQHIEIGYVQGMCDLLAPLLVILDDEALAFSCFTELMKRMNQNFPHGGAMDTHFANMRSLIQILDSELFELMHQNGDYTHFYFCYRWFLLDFKRELVYDDVFSVWETIWAAKHVSSAHYVLFIALALVEVYRDIILENNMDFTDIIKFFNEMAERHNAKQILQLARDLVHKVQILIENK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BPQ7-1", "uniprot_id": "SGSM1_MOUSE", "id": "Q8BPQ7-1", "name": "Small G protein signaling modulator 1", "aln": "--MASVPAEA-----------------ETRQRLLRTVKKEVKQIMEEAVTRKFVHEDSSHIISFCAAVEACVLHGLRRRAAGFLRSNKIAALFMKVGKGFPPAEELSRKVQELEQLIES---ARNQIQGLQENVRKLPKLPN-------------------------------LSPLAIKHLWIRTALFGRVLDKIVHYLVENSSKYYEKEALLMDPVDGPILASLLVGPCALEYTKMKTADHFWTDPSADELVQRHRIHSSHLRQDSPTKRPALCIQKRHSSGSMDDRPS---------ISARDYVESLHQDSRATLLYGKNNVLVQPRDDMEAVPGYLSLHQTADVMTLKWTPNQLMNGSVG---DLDYEKSVYWDYAVTIRLEEIVYLHCHQQ--VDSGGTVVLVSQDGIQRPPFRFPKGGHLLQFLSCLENGLLPHGQLDPPLWSQRGKGKVFPKLR--KRSPQGSSESTSSDKEDDEATDYVFRIIYPGTQSEFV-------------------------------------------------------PQDLMDVSMNNLPPLWQPSPRKSSCSSCSQSGSADGGSTNGCNHERAPLKLLCDNMKYQILSRAFYGWLAYCRHLSTVRTHLSALVNHMIVSPDLPCDAGQGLTASIWEKYIQDSTTYPEQELLRLIYYGGVQPEIRRAVWPFLLGHYQFGMTEMERKEVDEQIHACYAQTMSEWLGCEAIVRQRERESHAAALAKCS--------SGASLDSHLHRMLHRDSTISNESSQ-----------SCSSGRQ-NLRLQSDSSSST---------------------QVFESVDEVEQTEAEGRSEE--KHPKIPNGNPANGTCSPDSGHPSSHNFSSG-------LSEHS---EPSLS-----------------------------------------------------------TEDS--VLDAQRSLPAVFRPGDS------------SVEDGQSSE--------------ATTSRDEAPRE---------------------------------ELAVQDSLESDLLAN--------------------------------------------------------------------------------------ESLEEFMSIPGSLDVALPEK-----------------DGAVMDGWPG-EADKPSRADSEDNLSEEPEMESLFPALASLAVTSSANNEASPVSSSGVTYSPELLDLYTVNLHRIEKDVQRCDRSYWYFTAANLEKLRNIMCSYIWQHIEIGYVQGMCDLLAPLLVILDDEALAFSCFTELMKRMNQNFPHGGAMDTHFANMRSLIQILDSELFELMHQNGDYTHFYFCYRWFLLDFKRELVYDDVFSVWETIWAAKHVSSAHYVLFIALALVEVYRDIILENNMDFTDIIKFFNEMAERHNAKQILQLARDLVHKVQILIENK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q2NKQ1-1", "uniprot_id": "SGSM1_HUMAN", "id": "Q2NKQ1-1", "name": "Small G protein signaling modulator 1", "aln": "--MASAPAEA-----------------ETRQRLLRTVKKEVKQIMEEAVTRKFVHEDSSHIISFCAAVEACVLHGLRRRAAGFLRSNKIAALFMKVGKNFPPAEDLSRKVQDLEQLIES---ARNQIQGLQENVRKLPKLPN-------------------------------LSPLAIKHLWIRTALFEKVLDKIVHYLVENSSKYYEKEALLMDPVDGPILASLLVGPCALEYTKMKTADHFWTDPSADELVQRHRIHSSHVRQDSPTKRPALCIQKRHSSGSMDDRPS---------LSARDYVESLHQNSRATLLYGKNNVLVQPRDDMEAVPGYLSLHQTADVMTLKWTPNQLMNGSVG---DLDYEKSVYWDYAMTIRLEEIVYLHCHQQ--VDSGGTVVLVSQDGIQRPPFRFPKGGHLLQFLSCLENGLLPHGQLDPPLWSQRGKGKVFPKLR--KRSPQGSAESTSSDKDDDEATDYVFRIIYPGMQSEFVAPDFLGSTSSVSVGPAWMMVPAGRSMLVVARGSQWEPARWDTTLPTPSPKEQPPMPQDLMDVSVSNLPSLWQPSPRKSSCSSCSQSGSADGSSTNGCNHERAPLKLLCDNMKYQILSRAFYGWLAYCRHLSTVRTHLSALVNHMIVSPDLPCDAGQGLTARIWEQYLHDSTSYEEQELLRLIYYGGIQPEIRKAVWPFLLGHYQFGMTETERKEVDEQIHACYAQTMAEWLGCEAIVRQRERESHAAALAKCS--------SGASLDSHLHRMLHRDSTISNESSQ-----------SCSSGRQ-NIRLHSDSSSST---------------------QVFESVDEVEQVEAEGRLEE--KQPKIPNGNLVNGTCSPDSGHPSSHNFSSG-------LSEHS---EPSLS-----------------------------------------------------------TEDS--VLDAQRNTPTVLRPRDG------------SVDDRQSSE--------------ATTSQDEAPRE---------------------------------ELAVQDSLESDLLAN--------------------------------------------------------------------------------------ESMDEFMSITGSLDMALPEK-----------------DDVVMEGWRSSETEKHGQADSEDNLSEEPEMESLFPALASLAVTTSAN-EVSPVSSSGVTYSPELLDLYTVNLHRIEKDVQRCDRNYWYFTPANLEKLRNIMCSYIWQHIEIGYVQGMCDLLAPLLVILDDEALAFSCFTELMKRMNQNFPHGGAMDTHFANMRSLIQILDSELFELMHQNGDYTHFYFCYRWFLLDFKRELVYDDVFLVWETIWAAKHVSSAHYVLFIALALVEVYRDIILENNMDFTDIIKFFNEMAERHNTKQVLKLARDLVYKVQTLIENK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B2D5-1", "uniprot_id": "A0A8M3B2D5_DANRE", "id": "A0A8M3B2D5-1", "name": "", "aln": "--MANTTAEA-----------------ETRQRLLRNVKKEVKQIMEEAVTRKFVHEDSSHIVSFCAAVEACVLHGLKRRAAGFLRSNKIAALFTKVAKNFPPAEELCRKAQELELVFEN---RRSQSLSYSESTRKMPKVLN-------------------------------FSPQAVRHVWIHAALIEKVLDKIVLYLVENSSKFYEKEAILMDPVDGPILASLLVGPCALEYTKMKTADHFWTDPSADELVQRHRIHSGHCRQDSPTKRPALCIQKRHSSSSMDERPSP-------SPSARDYVESLHQNSRATLLFGKNNVLVQPRDDMEAVPGYLSLHQTADYMTLKWTPNQLMNGSVG---DLDYEKSVYWDYAMTIRLEEIVYLHCHQQ--VDCGGTVVLVSQDGIQRPPLRFPRGGHLLQFLSCLENGLLPHGQLDPPLWSQRGKGKVFPKLK--KRCPQGSSESVS-DKEEEEATDYVFRIVFPNSQSEFVTITHSTHLSLNS-----------RALWPPKCQTLVMPKHHRSSPGESPSSPEPSLAPELIDQGAN----MWHPTPRKSSCSSCSQNSFSDGAQPNGCNHERTPLKLLCDNMKNQIISRAFYGWLAYCRHLSTVRTHLSGLVNHTIVEPDVPSDAYSGLTTEVWQKFLQDCSTYEEKELLRLVYFGGVEPSLRKEVWPFLLGHYQFGMSETERKEVDEQMRACYEQTMSEWLGCEAIVKQKEKEQHAVALAKCS--------SGASMDSTTQRIMHRDSTISNESSQ-----------SCSSDRQRDSRLQSDSSSGTQFITSQKPFPWSSLLPFGLFLQVFESVEEVEQIESEPKNDVGKQVCKISNGTPQNGTSSPDSGHPSSRNFSVTSGQSDSLSTEDSGIHEPNLKSQPQLTASKEKAACCGEEGKETEERETKMVMKQGVREDNKTEVNKVLLDEVVTQESKKATEDSEVKMDISKTARDAFVASTADHSQVTKMEVGESLERSLTSENDALTRHTEPDIPKATEVMESTPPERKMNETRVRADIERPHKGIKDITAIREQPLIAKDLKVSDALEQKVVADIQVSVSEDTEKEATKTNETSKDNDSKTWMDEENNVRVLKPIDEKTSDLADEAGPTGKRKADMQRKAPVVEETVPLVHEAFSNRKMSEAQDETESDESPSAIEMEEIPTAKVWERKSSPKRRTTEQATIPALELRLEEAHGKLSSEEVNPEKPEMESLCPQLDSLAVNTEKIEASSPVSSIGTTYSQELLDMYTLNLHRIDKDVQRCDRNYWYFTPANLEKLRNIMCSYVWQHLEIGYVQGMCDLLAPLLVILDDEAMAFSCFTELMKRMNQNFPHGGAMDTHFANMRSLIQILDAELFELMHQNGDYTHFYFCYRWFLLDFKRELVYDDVFAVWETIWAAKCVSSSHFVLFIALSLVEIYRDIILENNMDFTDIIKFFNEMAEHHNIKQILTLSRDLVCKVQTLIENK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IQ31-1", "uniprot_id": "Q8IQ31_DROME", "id": "Q8IQ31-1", "name": "Small G protein signaling modulator 2", "aln": "MNMLHSFSGGGAGSAANASGDVSNAETELKERLIASVKKEVKQLMEEAVTKKYVHEESSSVTSLCGAVEACLSHGLRRRALGLFKTSSTTALIQKIAKICPEADYVSRRLLELELAQESHAVSGKRSSCSSDSIIKPKLLSKGSGSSNSVTTINTVTNGAGAG--PGGGGGASAPLG--KYLWIRLALHEKRLAKIIEHLVSNANSYYDREALVADPDYGSILSSLLVGPCALEFTRAKTADHYWSDPCADELVQRHRISS-GNRTPPTTHRP-IINFKRSLHTSSEDTSSGSFKACSPASVAKDYVESLHQNSRTTLLYGKNNVLVLPKDVSEPMPGYLSLHQSIQSLTIKWTPNQLMNGYNDGDGGD---KSFYWSYALNINVDEIVYVHCHQNRGGDTGGTIILVGQDGVQRPPIHFPEGGHLQAFLSCLETGLLPHGQLDPPLWSQRGIGKLFPWPKSVRRHILPSVMEAGGSVTDETPIDYVFRVVSKCQHEEFLASHPILELGRSS---------------------------------PRRKHLGSCSTTGSSDCSSK------SLSIDQSSCETPLIQAS-----------QSTSIELVCSTMRRQIISRAFYGWLAYCRHLSTVRTHLSGLVNGRIM-PDLAADE-EGLTRGKWLAMHEDGVVTGDLELYRLVYFGGVEPELRKEVWPYLLGHYDFGSTPEERKKQDETCKHYYETTMSEWLAVEAIVRQREKEKTALAVAKLSAEQARLAANATSSSNPHQKLANGSQQLQLEHGNGEEDQENLVLDEGENDVFDDNDFSDISDPGD---------------------LFDEPELGQEAEEQEQSNLEEEVFEKQEDEEDQEDHDQREMPRLSEKLVLEFQNID---NMEPLRLQENCFA-----------------------------------------------------------DSETENDLGLGLDSSGNILMLSI-----------KSSPSTSSYETVGNEF-----LDMAEAKLEEEEPP---------------------------------GQLSKFHSADDVRLD--------------------------------------------------------------------------------------NQDEEESSQP---ATAVIIT-------------------EAAS-LDALDDDPTEEFTSRKTSLMSPLNEDITVVASLDALQEPKSACVSPASSNGGVYSVELLEQFGLNLHRIEKDVQRCDRNYWYFANENLDKLRNVISTYVWEHLDVGYMQGMCDLVAPLLVIFDDESLSYSCFCKLMERMIENFPSGGAMDMHFANMRSLIQILDSEMYDLMDSNGDYTHFYFCYRWFLLDFKRELVYDDVFATWEVIWAAKHIASGHFVLFLALALLETYRDIILSNSMDFTDVIKFFNEMAERHNAQSILQLSRSLVLQLQTIIENK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IQ30-1", "uniprot_id": "Q8IQ30_DROME", "id": "Q8IQ30-1", "name": "", "aln": "--MVQGNADG----------------SDYKERLIASVKKEVKQLMEEAVTKKYVHEESSSVTSLCGAVEACLSQGLRRRALGLFKTSSTTALLHKIAKSCPEAEHISKLVQEIEASDPS-----KRSSSSSDSFQRPPMLKKSSSNSMSTGTNAAASTSSASASISVSASTSSMSLASMKYLWIRLALYEKRLTKIIEYLVSNASSFYDRDSLVADSDYGSILSSLLVGPCALEFTRAKTADHYWTDPHADELVQRHRISS-CRRSSSTCSRPAIINFKRSLNTSSDEAGTGSFKSIASASVAKDYVESLHQNAKATLLYGKNNVQVLPKDVAEPMPGYLSLHQHIQTLTIKWTPNQLMNGYTEAEEAEDIDKDAFWAYALNINVDEIVYVHCHQSRGEDSGGTVILVGQDGVQRPPIHFPEGGHMQQFLSCLETGLLPHGQLDPPLWSQRGIGKMFLWPRSMRRRILPSVMES----VDETPIDYVFRIVSKSRHEEFAATHSILDFVRST---------------------------------PRRAQLSSCSTTGSSDCSNK------SLSIDQFPMESPLILQQQQQQQQQLLQAQSTSIEMVCSTMRRQIISRAFYGWLAYCRHLSTVRTHLSGLVHGRIT-PEMKADE-EGLTKERWQLLNVNGVLENATEFYRLVYFGGVQPELRQEVWPYLLGHYAFGSTTEDRKKQDETCKHYYETTMSEWLAVDAIVQQREKEKTARAVAKLS-------SGSNSGNDRTVRAAD------LEAGG-----------DLENEVFED--ISDISDPGD---------------------LEFDEQQQQQQQQAECAVSGNHLTVKPIPRAMKTSTDSG----HVDESFNELDEPD---EEDNKQKQQQDEK-----------------------------------------------------------ISESESKLPDYRKLEEQINQEPS-----------CSASTASSYETVG--------PGEVHQRPNSDTRS---------------------------------VLSPEYLSADDLQLP--------------------------------------------------------------------------------------DDEDAVRPPPPPAAAAVIIT-------------------KASVDITNWERSPKAAEGDQMSPLEEQAGESGGAGVNMDALQQPKSACASPASSNGGVYSSELLEQFGLNLHRIEKDVQRCDRNYWYFANENLDKLRNVISTYVWEHLDVGYMQGMCDLVAPLLVIFDDESLSYSCFCKLMERMIENFPSGGAMDMHFANMRSLIQILDSEMYDLMDSNGDYTHFYFCYRWFLLDFKRELVYDDVFATWEVIWAAKHIASGHFVLFLALALLETYRDIILSNSMDFTDVIKFFNEMAERHNAQSVLQLARSLVLQLQMIIENK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : . : ::**: .*******:******:*:***:** : *:*.*****: :**:*** *::::.. :**: *:.* * *: :.: ::* . .: .:. : : : . :::**: ** : * **: :**.*:..:*:::::: *. *.**:**********:*: *****:*:** ********** * * .. ** : ** * :: : *:********::::***:***** * *:* *.:******** : :*:********** *. :* **:.*.::****:****. * ***::**.***:****::**.***: ******.***************** **:* : :* * . :: . *****:: :.** . * . . : : . .: : :.::::*..*: **:**********************.**: * *:: .* .*** * : *: **:*:**::*.:*: ***:***** ** : :**: ** : * **:***. :***:*:*:*. * *:** * .. * .. : . * . . .. : : . *... : : : * * . . .. . : : .:: : : * : * . :. . ..: : : . : . .. . *. *: **.** * .** ***: : :*****:********.****: **:****::.:*:*:*:::**:******:******:***::::*** :**:** :*** ***** *************:*:::**..**************************** .**.***** ::*.*:***:**:*:* ******.*.*****:*********:** :.:* *:*.** ::* :****", "identical_positions": 444, "similar_positions": 266, "identity": "29.72%" }, { "cls_id": "homologset.agr.RGD:1308179", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABZ3NNM8-1", "uniprot_id": "A0ABZ3NNM8_RAT", "id": "A0ABZ3NNM8-1", "name": "PrdX deacylase domain-containing protein 1", "aln": "-----------------MAGLELRAALEQRLGALAIRTEVVEHPEFLCVHILQVFTVEEMMPHIQHLKGAHSKNLFLKDKKKKSYWLVTVLHDRQINLNHLGKQLGVGSGNLRFADETAMLEKLKVGQGCATPLALFCD-DGDVKFVLDSAFLEGGHEKVYFHPMTNAATMGLSPEDFLVFVKATGHDPIILNFD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D820-1", "uniprot_id": "PRXD1_MOUSE", "id": "Q9D820-1", "name": "Prolyl-tRNA synthetase associated domain-containing protein 1", "aln": "-----------------MAGSELRAELEQRLGALAIRTEVVEHP--------EVFTIEEMMPHIQHLKGAHSKNLFLKDKKKKNYWLVTVLHDRQINLNDLGKQLGVGSGNLRFADETAMLEKLKVGQGCATPLSLFCD-DGDVKFVLDSAFLEGGHEKVYFHPMTNAATMGLSPEDFLIFVKATGHDPIILNFD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NEY8-1", "uniprot_id": "PRXD1_HUMAN", "id": "A6NEY8-1", "name": "Putative prolyl-tRNA synthetase associated domain-containing protein 1", "aln": "-----------------MAGAELGAALEQRLGALAIHTEVVEHP--------EVFTVEEMMPHIQHLKGAHSKNLFLKDKKKKNYWLVTVLHDRQINLNELAKQLGVGSGNLRFADETAMLEKLKVGQGCATPLALFCD-GGDVKFVLDSAFLEGGHEKVYFHPMTNAATMGLSPEDFLTFVKMTGHDPIILNFD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PFS2-1", "uniprot_id": "PRXD1_DANRE", "id": "Q6PFS2-1", "name": "Prolyl-tRNA synthetase associated domain-containing protein 1", "aln": "MDQSELVEAVSEAGGAAVAPVDLRKELEEFLKRLNIETTCIEHP--------EVFTVEEMMPHVSHLSGVVTKNLFLKDKKRR-VFLVCVRHDRPLALGELSRRLGAP--NLRLAEERLLLEKLRVRQGCVTPLALFLDTERSVTAVLDRELTHGGHTHIHCHPMTNSATMGITPADLLRFLEETQHTPVILSFD", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* :* **: * * *.* :*** :***:******:.**.*. :*********:: :** * *** : *..*.::**. ***:*:* :****:* ***.***:** * .*. *** : .*** ::: *****:****::* *:* *:: * * *:**.**", "identical_positions": 88, "similar_positions": 43, "identity": "45.13%" }, { "cls_id": "homologset.agr.RGD:1308183", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZU27-1", "uniprot_id": "D3ZU27_RAT", "id": "D3ZU27-1", "name": "ubiquitinyl hydrolase 1", "aln": "--------------------------------MSKVTAPAPGPGPPVAAGGKEKRSFSKRLFR--------------------------------SGRAGGS---------------GGAGGPGPAAPSSPSS---ARSVG---------------------------------SFMSRVLKTLSTLSHLSSEGAAPDRG---------GLRSCFPPGPASAPTPPPCP------------PPPASPAPPA----CASEPVPGVAGLRNHGNTCFMNATLQCLSNTELFAEYLALGQYRAGRPEPEPEPEQPAGRGPHGQGEVTEQLAHLVRALWTLEYTPQHSRDFKSIVSKNALQYRGNSQHDAQEFLLWLLDRVHEDLNHAVKQSGQPPLKPPSETDMMPEGPSFPVCS----TFVQELFQAQYRSSLTCPHCQKQSNTFDPFLCISLPIPLPHTRPLYVTVVYQGKCSHCMRIGVAVPLSGTVARLREAVSMETKIPTDQIVLTEMYYDGFHRSFSDTDDLETVHESDCIFAFETPEIFRPEGILSQRGIHLNNNLNHLKFGLDHHRLSSSTPTAAKQGRVDLPS-RVASDKIVLLVCN--RACTGQQGKRFGLPFVLHLEKTVAWDLLQKEILEKMKYFLRPTVSVQVCPFSLRVVSVVG-----ITYLLPQEEQPLCHPTVERALKSCG-PGGTAHVKLVVEWDKETKDFLFVN--TEDEYIPDAESVRLQKEQHHQPQTCTLSQCFQLYTKEERLAPDDAWRCPHCKQLQQGSITLSLWTLPDVLIIHLKRFRQE---GDRRMKLQNMVKFPLTGLDMTPHVVKRSQSSWS------------LPSHWSPWRRPYGLGR---------DPEDYIYDLYAVCNHHG-TMQGGHYTAYCKNSVDGLWYCFDDSDVQQLSED----EVCTQTAYILFYQRRTAIPSWSANSSVAGSTSSSLCEHWVSRLPGSKQASVTSAASSRRTSLASLSESVEMTGERSEDDGGFSTRPFVRSVQRQSLSSRSSVTSPLAVNENCMRPSWSLSAKLQMRSNSPSRFSGDSPIHGSASTLERIGEAGDDKVSISCFGSLRNLSGSHQEPSDSHSRREHKAAGRAPLAVMEGVFKDDSDSGKLNSSVVDTPSKNRAQGDHLPPVSDPFDNNNQIAYVDQSDSVDSSPVKEVKSPSHSDSLTKKPESTTKRSPSSKGASEPEKSMRKGRPALASQESSLSSPSPSSPVPVKVSMKPARCRSKADSS-RTSGRHSSSASTQPKKESSPRSQESMSSPSPQKQKSASAFTYSSSSISAKTAPGPATRGPLPSGKSRTSDRSLSRQGSRQSLGSDRASVTSTSTSKPSSPRVNQARAGDSRVDGKHVRSSSMASLRSPSTSVRSGLKRDSKSEDKGLSFFKSALRQKETRRSTDLGKTTLLSKKAGGSSVKSVSKNTADDKAEKGHQPPGSQQPNTNTTGKEQLVSKDPASAKHSLLSARRSKSSQVDSGAPLSPSSRSTTEKGSKKLSSSMQTSARPSHKPQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q6Y8-1", "uniprot_id": "E9Q6Y8_MOUSE", "id": "E9Q6Y8-1", "name": "ubiquitinyl hydrolase 1", "aln": "--------------------------------MSKVTAP--GPGPPVAAGGKEKRSFSKRLFR--------------------------------SGRAGGG---------------GGAGGPGPAAPSSPSS---ARSVG---------------------------------SFMSRVLKTLSTLSHLSSEGAAPDRG---------GLRSCFPPGPASAPTPPPCP------------PPPASPAPPA----CASEPVPGVAGLRNHGNTCFMNATLQCLSNTELFAEYLALGQYRAGRPEPEPESEQPAGRGPHGQGEVTEQLAHLVRALWTLEYTPQHSRDFKSIVSKNALQYRGNSQHDAQEFLLWLLDRVHEDLNHAVKQSGQPPLKPPSETDMMPEGP-FPVCS----TFVQELFQAQYRSSLTCPHCQKQSNTFDPFLCISLPIPLPHTRPLYVTVVYQGKCSHCMRIGVAVPLSGTVARLREAVSMETKIPTDQIVLTEMYYDGFHRSFSDTDDLETVHESDCIFAFETPEIFRPEGILSQRGIHLNNNLNHLKFGLDHHRLSSPAPTAAKQGRVDLPT-RVASDKIVLLVCN--RACTGQQGKRFGLPFVLHLEKTVAWDLLQKEILEKMKYFLRPTVSIQVCPFSLRVVSVVG-----ITYLLPQEEQPLCHPTVERALKSCG-PGGTAHVKLVVEWDKETKDFLFVN--TEDEYIPDAESVRLQKEQHHQPQTCTLSQCFQLYTKEERLAPDDAWRCPHCKQLQQGSITLSLWTLPDVLIIHLKRFRQE---GDRRMKLQNMVKFPLTGLDMTPHVVKRSQSSWS------------LPSHWSPWRRPYGLGR---------DPEDYIYDLYAVCNHHG-TMQGGHYTAYCKNSVDGLWYCFDDSDVQQLSED----EVCTQTAYILFYQRRTAIPSWSANSSVAGSTSSSLCEHWVSRLPGSKQASVTSAASSRRTSLASLSESVEMTGERSEDDGGFSTRPFVRSVQRQSLSSRSSVTSPLAVNENCMRPSWSLSAKLQMRSSSPSRFSGDSPIHGSASTLERIGEAGDDKVSISCFGSLRNLSGSHQEPSDSHNRREHKAVGRAPLAVMEGVFKDDSDPGKLNSSVVDTPSKNRAQGDHLPPVSDPFDNNNQIAYVDQSDSVDSSPVKEVKPPSHSDSLTKKPESTTKSSPSSKGTSEPEKNMRKGRPALASQESSLSSPSPSSPVPVKVSMKPARCRSKADSS-RTSGRHSSSSSTQPKKESSPRSQESMSSPSPQKQKSASAFTYSSSSISAKKAPSPVTRGPFPSGKSRTSDRSLSREGSRQSLGSDRASVTSTSTSKPSSPRVNQARAGDNRVDGKHVRSSSMASLRSPSTSVRSGLKRDSKSEDKGLSFFKSALRQKETRRSTDLGKTTLLSKKAGGSSVKSVSKNTADDKTEKGHQPPGSQQPNTNAVGKEQLVSKDP--AKHSLLSARRSKSSQLDSGAPLSPSSRSTTEKGSKKLSSSMQTSARPSQKPQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q70CQ4-1", "uniprot_id": "UBP31_HUMAN", "id": "Q70CQ4-1", "name": "Ubiquitin carboxyl-terminal hydrolase 31", "aln": "--------------------------------MSKVTAP--GSGPPAAASGKEKRSFSKRLFR--------------------------------SGRAGGGG-------------AGGPGASGPAAPSSPSSPSSARSVG---------------------------------SFMSRVLKTLSTLSHLSSEGAAPDRG---------GLRSCFPPGPAAAPTPPPCP------------PPPASPAPPA----CAAEPVPGVAGLRNHGNTCFMNATLQCLSNTELFAEYLALGQYRAGRPEPSPDPEQPAGRGAQGQGEVTEQLAHLVRALWTLEYTPQHSRDFKTIVSKNALQYRGNSQHDAQEFLLWLLDRVHEDLNHSVKQSGQPPLKPPSETDMMPEGPSFPVCS----TFVQELFQAQYRSSLTCPHCQKQSNTFDPFLCISLPIPLPHTRPLYVTVVYQGKCSHCMRIGVAVPLSGTVARLREAVSMETKIPTDQIVLTEMYYDGFHRSFCDTDDLETVHESDCIFAFETPEIFRPEGILSQRGIHLNNNLNHLKFGLDYHRLSSPTQTAAKQGKMDSPTSRAGSDKIVLLVCN--RACTGQQGKRFGLPFVLHLEKTIAWDLLQKEILEKMKYFLRPTVCIQVCPFSLRVVSVVG-----ITYLLPQEEQPLCHPIVERALKSCG-PGGTAHVKLVVEWDKETRDFLFVN--TEDEYIPDAESVRLQRERHHQPQTCTLSQCFQLYTKEERLAPDDAWRCPHCKQLQQGSITLSLWTLPDVLIIHLKRFRQE---GDRRMKLQNMVKFPLTGLDMTPHVVKRSQSSWS------------LPSHWSPWRRPYGLGR---------DPEDYIYDLYAVCNHHG-TMQGGHYTAYCKNSVDGLWYCFDDSDVQQLSED----EVCTQTAYILFYQRRTAIPSWSANSSVAGSTSSSLCEHWVSRLPGSKPASVTSAASSRRTSLASLSESVEMTGERSEDDGGFSTRPFVRSVQRQSLSSRSSVTSPLAVNENCMRPSWSLSAKLQMRSNSPSRFSGDSPIHSSASTLEKIGEAADDKVSISCFGSLRNLSSSYQEPSDSHSRREHKAVGRAPLAVMEGVFKDESDTRRLNSSVVDTQSKHSAQGDRLPPLSGPFDNNNQIAYVDQSDSVDSSPVKEVKAPSHPGSLAKKPESTTKRSPSSKGTSEPEKSLRKGRPALASQESSLSSTSPSSPLPVKVSLKPSRSRSKADSSSRGSGRHSSPAPAQPKKESSPKSQDSVSSPSPQKQKSASALTYTASSTSAKKASGPATRSPFPPGKSRTSDHSLSREGSRQSLGSDRASATSTS--KPNSPRVSQARAGEGRGAGKHVRSSSMASLRSPSTSIKSGLKRDSKSEDKGLSFFKSALRQKETRRSTDLGKTALLSKKAGGSSVKSVCKNTGDDEAERGHQPPASQQPNANTTGKEQLVTKDPASAKHSLLSARKSKSSQLDSGVPSSPGGRQSAEKSSKKLSSSMQTSARPSQKPQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W117-1", "uniprot_id": "Q9W117_DROME", "id": "Q9W117-1", "name": "ubiquitinyl hydrolase 1", "aln": "MGTTKERREQSEGDAATTHLTTTATATTGAIVAAGVTTTLPATKTTTTAADTSTTNAAKKIRRTFSMPRNPFRWTRKFKTAVAVTSSAGAENDNESGKNNGARERRGSHTAISSCVGGGRGRSGSIVSLSSYEAPFISSTNNNTTTASNGNNNNSSSSNINSKRTRALRRSSFRKFLNRIAQHLSSTVNVVSEEKHSPANRIAFIEIVPFYTGCWRRKEANKHGQPSVSGSSSGGGGGAGGPGGGERVPPIGGYQWPADQTPGVMGLKNHGNTCFMNAVLQCLSHTDILAEYFVLDQYKADLKRRNKINSRKFG----TKGELTEQLANVLKALWTCKNESDHSTSFKAVVDRYGTQFRSSTQHDAQEFLFWLLDKVHEDLNTASKRRYKSLKNSYGRSDEVIAAETLANHIRCNNSFVQAVFQAQFRSSLTCPRCEKQSNTFDPFHCISVQLPQLTQQTIFVTVVYMTRLPRQVRMGLRVPAGSPIVALREQLQADTGIEGSRMVLVDLNAEGFTRVFYDTQPVETLSSIETIYCIEVPAATPVAKAATP---------------------SETGDKSAPTAVTPSPAAAQSQADLLLLVANVYRAKDGADITRFGAPFSMKAPRDCSYQDLQKRMLREMAPLLKPEVFSYATPLAEMFRIRLQDPSADPDTYLEQVEHPLLTEMIDMALSVLSSEAGPQHIKLLLEWSSPEAHFISKQQDTEEAVVEHESVARLSASKPSDTAALTLEQCLEHYTKAETLSAEDAWRCPHCQQYLPVVKTLGLWSLPDILVVHFKRFRQHQSKGPQAAKLTTMVKFPLTAFDMSPHLARGVHESASSSLGMGTGIGLGLGLGSNPWKKARSVDSRSSTLNSRCDAKDTRYDLYAVCYHQGDTLETGHYTAACKNPYDRQWYKFDDQRVSKVPEDDIEQDIINNEAYMLFYQRR------SVDAGECSGSSSNSGDHWVSRIAPASSSSASSTSGKERE--------------------------------------------PVKLEENTESP----------------------------AAVEVTEKAQSKPVDIVCQDKAK-------GTADGPDADQEQTTVPHDLQIEELAFADADVDTSLGETIKAEVN---------------------LAAKDEPKKVEVEEATPIFAMDEDGSEARQEK----------------------KEECVKKEDELSEAPDVSELTAES---------------KTNGHVSSSSSSS----SSESSLSSRSSP-----RSLSTSVTAASTLQSKFNGHMSAAPALFNGNGNTSQLSSSLQLSRHVLHNHQWHGSRSSVSAVENATQHQQQQAAASLSLRHSFSTSSN----YTETLSSLLRKSANTCSKDTLLFIDQQSHHHTAGLIEDDDDSYMGRSLWISPVTPHKLITVSPKN---------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : **:. .. ...:*..... . :*:: * **: .*. ** * .*. .. *. . *.. .*:.*: : **: :: ** . . .*: * *. . * .. .** .:: .*** **:**********.*****:*:::***:.*.**:*. . . .: * :**:*****::::**** : .:** .**::*.: . *:*..:********:****:****** : *: :. :. ..:* : . :. :*** :****:*******:*:********* ***: :* :.::***** : .: :*:*: ** ...:. *** :. :* * .::**.:: :** * * **: :**: . : *:.:*.* : *.. .:* . *: .. .::***.* ** * : .*** ** :: : ::: ***.:*.:* :*:* * . *:: . : * * *:** :: **. . .*. *:**::**.. .*: : **: : . . .**. .: :. : **.**:: *** * *:.:********:* **.**:***:*::*:*****. * : ** .*******.:**:**:.: :.* * * .**::. .:. *.:* ******* *:* *:: ***** ***. * ** ***. *.::.** :: .: **:****** *.::. ...:**. :*****:. :. :*.:*::...* *: ::** * :::* :* .. *.* * .. : .:*. . :.::. * : * .* * . *..:: . :* *:...*: . .. : . .. .* ::: : : ..:*..**... * :..: : .*: **.:.:. ** * .* *** :* *: . ::*: .:* : .: *:..**: * * : **: * ..: : :* ... * : . :* *:* : :: * *::.::: .*. :* . ::.* : .. : :.:. *.*.. * . : ", "identical_positions": 347, "similar_positions": 395, "identity": "22.62%" }, { "cls_id": "homologset.agr.RGD:1308184", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4A332-1", "uniprot_id": "D4A332_RAT", "id": "D4A332-1", "name": "Structure-specific endonuclease ANKLE1", "aln": "-MADASSLSLQLLAALREEEARAVEKLLRLGADPN--LVLDDGAAAVHLAARASHPRALHCLRMLLRWG--ADPNARSAEALTPVHVAAAWGCCSALELLLSRGGDPTLRDQDGLRPLDWALQQQHHNCARVLRELDTPT------RKPNET------------------------------------PKPTAG----------------------------------------------------------------SPGASQDSELHMHR--AELEVEAVEVAVQPQSPEATESSDYS----------------------------------------------------SDASFVTAVEDS-------------------------------------LQPRRPGGICELMASLWVTRGAASAGEGAPNCQSQALTLT---------------------EKSTDKPLLLGDGDLGALHPHGS--------------------------------VPPMSDLQLLQALRALGYSPGPVTPFTRGHYLRR----------------------LQEAQAS-----PGHSPELAEALRTG----TVPDCQVDEAALAQHFQRPDPSRK-WREGITKSSFTYLLLDPRL----------------TKDLPARASSLTLAQCLQCFVRAIFYVGKGTRARPDAHLWEARGYHDQPRKQ--------------------------------VCPKIRRILDIWDSGRGIISLHCFQHVVAVEAYTREACLLDALGLQTLTNQKQGHYYGVVAHWPLPRRRRLGVYL---------------------------------------------------LQRALLVFLAEGERELRPQDIQARG----------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A8VU90-1", "uniprot_id": "ANKL1_MOUSE", "id": "A8VU90-1", "name": "Structure-specific endonuclease ANKLE1", "aln": "-MADTACLALRLLAALREEEARAVEELLRLGADPN--LVLDDGAAAVHLAARASHPRALHCLRMLLRWG--ADPNARSAEGLTPVHVAAAWGCCGALELLLSRGGDPTLRDQDGLRPLDWALQQRHHNCARVLQELDTPTQP-DETREPTET------------------------------------FHVAQGSF--------------------------------------------------ETETCQGPALAESSGVSQDSELHVHR--AELEVEAVEVAVHPQSSEATENSDYS----------------------------------------------------SDASFVTAVEDS-------------------------------------LQPGRPGGALELVAGLWVTRGAVSAGKGAPNCQPQVLTLT---------------------ARDTDKPVLPGDGDLGALHPHSS--------------------------------VPPMSDLQLLQALRALGYSPGPVTPFTRGHYLRR----------------------LQEAQASRAD--VGHSQELAEALRTG----TIPDCQVDEEALAQCFQRLDPLKK-WREGITKSSFTYLLLDPRL----------------TKDLPARASSLTLAECLQCFVRAIFYVGKGTRARPDAHLWEAFGYHDQPRKQ--------------------------------VCPKVRRILDIWASGRGIISLHCFQHVVAMEAYTREACLLDALGLQTLTNQKQGHYYGVVAHWPPSRRRRLGVHL---------------------------------------------------LQRALLVFLAEGERELRPQDIQARG----------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NAG6-2", "uniprot_id": "ANKL1_HUMAN", "id": "Q8NAG6-2", "name": "Structure-specific endonuclease ANKLE1", "aln": "-MCSEARLARRLRDALREEEPWAVEELLRCGADPN--LVLEDGAAAVHLAAGARHPRGLRCLGALLRQG--GDPNARSVEALTPLHVAAAWGCRRGLELLLSQGADPALRDQDGLRPLDLALQQGHLECARVLQDLDTRTRTRTRIGAETQE------------------------------------PEPAPGTPGLSG-------------------------------------------PTDETLDSIALQKQPCRGDNRDIGLEADPGPPSLPVPLETVDKHGSSASPPGHWDYS----------------------------------------------------SDASFVTAVEVSGA----------------------EDPASDTPPWAGSLPPTRQGLLHVVHANQRVPR--SQGTEAELNARLQALTLTPPNAAGFQSSPSSMPLLDRSPAHSPPRTPTPGASDCHCLWEHQTSIDSDMATLWLTEDEASSTGGREPVGPCRHLPVSTVSDLELLKGLRALGENPHPITPFTRQLYHQQ----------------------LEEAQIAPGPEFSGHSLELAAALRTG----CIPDVQADEDALAQQFEQPDPARR-WREGVVKSSFTYLLLDPRE----------------TQDLPARAFSLTPAERLQTFIRAIFYVGKGTRARPYVHLWEALGHHGRSRKQPHQ-----------------------------ACPKVRQILDIWASGCGVVSLHCFQHVVAVEAYTREACIVEALGIQTLTNQKQGHCYGVVAGWPPARRRRLGVHL---------------------------------------------------LHRALLVFLAEGERQLHPQDIQARG----------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VIE0-1", "uniprot_id": "Q9VIE0_DROME", "id": "Q9VIE0-1", "name": "LEM domain-containing protein", "aln": "MEQRANFLALTLLDALEDENEADIMSMLERNSINAGIVPCDRGLAPLHYVCGMRNGGLAQRILERFLECPDLDVNALCDGQTTALHIASIYGRTELVRMLLERGACADLADEDNKLPVHYAIEECHFEVLQLLRDHIFRERQIQKKQQQRVQ------------------------------------VVDALTPNQPRYNHDVTSPYYINITHRRHRPQPKFPEPTEVECADIPPLPDEESVNLFALTEAHLTQLIQSQRQNQPEDPCQPKRRTLIESWREKVERSRARQSLFHQYDEH----------------------------------------------------VEAMVDDAISQEDFNYKEHLQKKLRDEDNSKNLTEDAPNSGRQVFEMLVEQVSQAVVVEPEPEHSFFTAQGDEVDVAESSARQDEYFLQIKEAYVHTDDENGLVFYEARYLQNRDRREPVEQTPKERKHDLESSVSTNYTL------------------------PLDYETDALRRELTQLGAPVGPITKTTKRLYIKQLIKYKRNTE------------ALLAAQKHAQDAQIRYSVELHRTLRSPEDFARINDYLPHEATSAAHFAQCGVTKKNMREGHLKQSFIYMLIDPRI----------------SRNLPGESAFLEKFGVWQRFLDSIFYIGKGKCSRPYAHLYDAMRQHTRLHQKREKDKTNRERGGGFRTLQPDVFRSPPPGDGKMGSRKLERILDIWQHGSGVVCLHVFHNILPIDAYTREASIIDALGLNHLTNIKRGDYYGPAQSWTMKQKKQLGIAL---------------------------------------------------LFKAMHIYLAEGESQLSPSDLL-------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "B7YZH2-1", "uniprot_id": "B7YZH2_DROME", "id": "B7YZH2-1", "name": "LEM-3-like GIY-YIG domain-containing protein", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSKLLVFNFIQTIPLQLRNNFKSKVKAR---------------------------PISYSLGTLHKHHTN-------------------------------------------------------FSTELENTINSESNFKNISNLIKFVRQHSKWYRDNDCINR--------HYFNYILLDPRV----------------TNNLKERASQLHLMDVWYTFLRAIFYVGKGKATRPYVHLKNAQKLVDETNN-------------------ITLVKDP----------KLALIVSIWKANRGVLLIRAFQGISSQDAQTREASIIDALGMNHLTNRRLGFYYGRARSLSDKERKYLGIAL---------------------------------------------------LYKLMMKFLAKEEKELFPLKNTKAAMAA-------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0AB32TCT7-1", "uniprot_id": "A0AB32TCT7_DANRE", "id": "A0AB32TCT7-1", "name": "", "aln": "--MSGAKLEHLLAEAVSEADARSVLCLLGRGADPN--RIMCDGVAAVHLAAGRESERGLRCLKLMLEHG--ADANLRSAEALTPLHIAASWGCLQNLRLLLRNGGNPNLRDQDGNRASDLAEQEDNSKCASLLLEHELLTHTQEDDAPRFHYSLLSEDSVLSSTHLSSISRTSDKHRETAALWLSELVEEPVMSSTCVSAVDPVLLSAHTDAHTDAHTDAHTDAHTDAHTDAHTDAHTDAHTDAHTDAQTDCEVSPSFPGRSQQELQKSLRAADEYFSILCPHPQLHPSADSTFDLSQYSGFLHGERTAAVRQNQGIDVTSPDEVFVFSKDVDAEDEFDKTVVGPAARDEDEDDEEFKSVFQPPLSSGSSQYTSCGSDSFHSPVLEHQRLPDPQNPDNAPGEQERRSARPLEEPQGSRTAEDHCQGEEIEDDCVPSPFVTGRTRSRLSRCSQRMSQKLSSSDSSSLLFEQPLPSAERRHTKKRQNREPERDHRRRGGGGGVQELEEELESRLHSLCLSEHSSARSPADTLTHTQTESEADTVIIPDHSEDTQRSVRASPQRSVRASPQRSVRASPQRSVCAAPGPSGCTPRYSMSRLSGRSGRQALKNTCTSVAPPSPVAPPSPADELEQYLYTDTEEGQQLIETRVPPTCADDTLLYDWRSLTHPSPERSAGAHTAHTLTDTELRHTLLQMGEQPGPINTLTRPLYLQKLRRVLQTSDPAHACG-------THTHKHTHICRTHTLTDITLHRLVVYDVCACVRVCVCVRACVCVCVCAHVRVCVCARLCVCVCVRARACTCACVCAPVRVCVRVCARLYVCVCVRVSACACVCACMCVCVCACVCLRACLCVCVRLYVCVCVHACLCVCVCLYVCVCVCMCVCARMYVCVRVCVRACVCVCVCVSACACLRVRVCVCVRVCVCVCVCVCVCVCVCVCVCVCVCVCVRARACTCVCVCVCVRAHVCVCACLRVCVCVCV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . : . : : . . . . *::.* :. .: : * . * * . . .: :: : : : . ...: * : .. : : : : * : :. ", "identical_positions": 7, "similar_positions": 44, "identity": "0.71%" }, { "cls_id": "homologset.agr.RGD:1308185", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9GZM5-1", "uniprot_id": "YIPF3_HUMAN", "id": "Q9GZM5-1", "name": "Protein YIPF3", "aln": "MATTAAPAGGARNGAGPEWGGFEEN-IQGGGSAVIDMENMDDTSGSSFEDMGELHQRLREEE-VDADAADAAAAEEEDGEFLGMKGFKGQLSRQVADQMWQAGKRQASRAFSLYANIDILRPYFDVEPAQVRSRLLESMIPIKMVNFPQKIAGELYGPLMLVFTLVAILLHGMKTSDTIIREGTLMGTAIGTCFGYWLGVSSFIYFLAYLCNAQITMLQMLALLGYGLFGHCIVLFITYNIHLHALFYLFWLLVGGLSTLRMVAVLVSRTVGPTQRLLLCGTLAALHMLFLLYLHFAYHKVVEGILDTLEGPNIPPIQRVPRDIPAMLPAARLPTTVLNATAKAVAVTLQSH--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3UDR8-1", "uniprot_id": "YIPF3_MOUSE", "id": "Q3UDR8-1", "name": "Protein YIPF3", "aln": "MATPAAPASGVRNGAGPEWGGFEEN-IQGGGSAVIDMENMDDTSGSSFEDMGELHQRLREEE-VDADAA---AAEEEDGEFLGMKGFKGQLSRQVADQMWQAGKRQASRAFSLYANIDILRPYFDVEPAQVRSRLLESMIPIKMVNFPQKVAGELYGPLMLVFTLVAILLHGMKTSDTIIREGTLMGTAIGTCFGYWLGVSSFIYFLAYLCNAQITMLQMLALLGYGLFGHCIVLFITYNIHLHALFYLFWLLVGGLSTLRMVAVLVSRTVGPTQRLLLCGTLAALHMLFLLYLHFAYHKVVEGILDTLEGPNIPPMQRVPRDIPAVLPAARLPVAVINATAKAIAVTLQSH--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6TUD4-1", "uniprot_id": "YIPF3_RAT", "id": "Q6TUD4-1", "name": "Protein YIPF3", "aln": "MATQAAPASGVRNGAGPEWGGFEEN-IQGGGSAVIDMENMDDTSGSSFEDMGELHQRLREEE-VDADAA---AAEEEDGEFLGMKGFKGQLSRQVADQMWQAGKRQASKAFSLYANIDILRPYFDVEPAQVRSRLLESMIPIKMVNFPQKVAGELYGPLMLVFTLVAILLHGMKTSDTIIREGTLMGTAIGTCFGYWLGVSSFIYFLAYLCNAQITMLQMLALLGYGLFGHCIVLFITYNIHLHALFYLFWLLLGGLSTLRMVAVLVSRTVGPTQRLLLCGTLAALHMLFLLYLHFAYHKVVEGILDTLEGPNIPPMQRVPRDIPAVLPAAKLPVAVVNATAKAIAVTLQSH--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q803Z2-1", "uniprot_id": "YIPF3_DANRE", "id": "Q803Z2-1", "name": "Protein YIPF3", "aln": "----MSASQGSKNTNAEPWGGFDDNIIQGTGSAVIDMENMDDTSGSSFEDVGEMHQRMREEEEVTAEAAATEEDNGEYGEFLGMKGLKGQLGRQVADEVWQAGKRQASKAFNLYANIDILRPYFDVEPIQVRNRLVESLIPVRMINFPQKVAGELYGPMMLVFTLVAILLHGMKTSGTVIREGTLMGTAIGTGFGYWLGVSSFIYFLAYLCNAQITMLQMLSLLGYGLFGHCVVLFITYNVHFHSLFYLLWMVIGGLSTLRMVAVLISRTVGQTPRLILCGSLAALHMLFLLYLHFAYHKMVEGILDTLEGPNIPPIQRVARDVPVVA------SAVVNATVKSIAAIVQSQQL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.: * :* . ****::* *** ********************:**:***:**** * *:** : * ********:****.*****::*********:**.**************** ***.**:**:**::*:*****:*******:*****************.*:************* ****************************:**********:*******:*:*:****:*:::************:***** * **:***:******************:***************:***.**:*.: :*:***.*::*. :**: ", "identical_positions": 263, "similar_positions": 54, "identity": "74.29%" }, { "cls_id": "homologset.agr.RGD:1308187", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BSU7-1", "uniprot_id": "MOB3A_MOUSE", "id": "Q8BSU7-1", "name": "MOB kinase activator 3A", "aln": "-----------------------------------------------MSNPFLKQVFNKDKTFR---------------------PKR--------------KFEPGTQRFELHKRAQASLNAGLDLR--------------LAVQLPPGEDLNDWVAVHVVDFFNRINLIYGTISDGCTEQSCPVMSGGPKYEYRWQDEQRFRKPTALSAPRYMDLLMDWIEVQINNEDIFPTNVGTPFPKTFLQ-AVRKILSRLFRVFVHVYIHHFDRIAQMGSEAHVNTCYKHFYYFVTEFNLIDPKELEPLKEMTSRMCH---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B5DEX8-1", "uniprot_id": "B5DEX8_RAT", "id": "B5DEX8-1", "name": "", "aln": "-----------------------------------------------MSNPFLKQVFNKDKTFR---------------------PKR--------------KFEPGTQRFELHKRAQASLNAGLDLR--------------LAVQLPPGEDLNDWVAVHVVDFFNRVNLIYGTISDGCTEQSCPVMSGGPKYEYRWQDEQRYRKPTALSAPRYMDLLMDWIEVQINNEDLFPTNVGTPFPKTFLQ-AVRKILSRLFRVFVHVYIHHFDRIAQMGSEAHVNTCYKHFYYFVTEFSLIDPKELEPLKEMTSRMCH---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96BX8-1", "uniprot_id": "MOB3A_HUMAN", "id": "Q96BX8-1", "name": "MOB kinase activator 3A", "aln": "-----------------------------------------------MSNPFLKQVFNKDKTFR---------------------PKR--------------KFEPGTQRFELHKKAQASLNAGLDLR--------------LAVQLPPGEDLNDWVAVHVVDFFNRVNLIYGTISDGCTEQSCPVMSGGPKYEYRWQDEHKFRKPTALSAPRYMDLLMDWIEAQINNEDLFPTNVGTPFPKNFLQ-TVRKILSRLFRVFVHVYIHHFDRIAQMGSEAHVNTCYKHFYYFVKEFGLIDTKELEPLKEMTARMCH---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VL13-1", "uniprot_id": "MOB3_DROME", "id": "Q9VL13-1", "name": "MOB kinase activator-like 3", "aln": "-----------------------------------------------MALNGFLEFFQKGKTFR---------------------PKK--------------PFASGTIRYSLHKQAQASLQSGINLR--------------QVVRLPQGENLNDWLAVHVVDFFNRINLIYGTVSEFCNETTCPTMSGGSRYEYLWADGDLYKKPTALSAQKYIEHLMDWIETQINNEAVFPVSTDVPFPKNFIA-ISRKILTRLFRVFVHVYIHHFDRIVSIGAEAHVNACYKHFYYFVQEFDMISAKELEPLQEMTSRICKDKD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40484-1", "uniprot_id": "MOB1_YEAST", "id": "P40484-1", "name": "DBF2 kinase activator protein MOB1", "aln": "MSFLQNFHISPGQTIRSTRGFKWNTANAANNAGSVSPTKATPHNNTINGNNNNANTINNRADFTNNPVNGYNESDHGRMSPVLTTPKRHAPPPEQLQNVTDFNYTPSHQKPFLQPQAGTTVTTHQDIKQIVEMTLGSEGVLNQAVKLPRGEDENEWLAVHCVDFYNQINMLYGSITEFCSPQTCPRMIATNEYEYLWAFQ-KGQPPVSVSAPKYVECLMRWCQDQFDDESLFPSKVTGTFPEGFIQRVIQPILRRLFRVYAHIYCHHFNEILELNLQTVLNTSFRHFCLFAQEFELLRPADFGPLLELVMELRDR--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : ::: * **: : .. : *: :* ::: : ::: .*:** **: *:*:*** ***:*::*::**:::: *. :** * . .*** * : *.::** :*:: ** * : *:::* :** .. .**: *: : ** *****:.*:* ***:.* .:. :: :*:.::** *. ** :: . :: ** *:. .: . ", "identical_positions": 66, "similar_positions": 81, "identity": "20.82%" }, { "cls_id": "homologset.agr.RGD:1308188", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4A9N9-1", "uniprot_id": "D4A9N9_RAT", "id": "D4A9N9-1", "name": "Uridine phosphorylase", "aln": "MASILP-------------ASNRTMRPD--KNPYER------ERSVYVRNPHLDAMDEGILYHLDLGTK----THNLPAMFGD--FVCVGGSSNRMKAFALFMHKELGLEG-DGDDIEDICAGTDRYCMFKTGPVLSLSHGMGIPSISIMLHELIKLLHHARCCDVTIIRIGTSGGIGIAPGSVVITDTAVDSFFKPRFEQVILDNVVTRSTELDKELATDLFNCSREIPN-FLTLIGHTMCTYDFYEG--RLDGALCCFSREKKLDYLKRAYKAGVRNIEMESTVFAAMCGLCGLRAAVVCVTLLDRLESDQINLSHDVLVEYQQRPQLLISNFIKKQLGLCDQMS--------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CGR7-1", "uniprot_id": "UPP2_MOUSE", "id": "Q8CGR7-1", "name": "Uridine phosphorylase 2", "aln": "MASILP-------------ASNRSMRPD--KNTYER------KRSVYVKNPYLEGMDEDILYHLDLGTK----THNLPAMFGDVKFVCVGGSPNRMKAFAQFMHKELRLEG-DGEDIEDICAGTDRYCMFKTGPVLSVSHGMGIPSISIMLHELIKLLHHAHCCDVTIIRIGTSGGIGIAPGSVVITDTAVDSFFKPRFEQVILDNVVTRSTELDKELANDLFNCSREIPN-VPTLIGHTMCTYDFYEGQGRLDGALCSFSREKKLDYLKRAYRAGVRNIEMESTVFAAMCGLCGLRAAVVCVTLLDRLESDQINLSHDVLVEYQQRPQLLISNFIKKQLGLCDQMS--------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95045-1", "uniprot_id": "UPP2_HUMAN", "id": "O95045-1", "name": "Uridine phosphorylase 2", "aln": "MASVIP-------------ASNRSMRSD--RNTYVG------KRFVHVKNPYLDLMDEDILYHLDLGTK----THNLPAMFGDVKFVCVGGSPNRMKAFALFMHKELGFEE-AEEDIKDICAGTDRYCMYKTGPVLAISHGMGIPSISIMLHELIKLLHHARCCDVTIIRIGTSGGIGIAPGTVVITDIAVDSFFKPRFEQVILDNIVTRSTELDKELSEELFNCSKEIPN-FPTLVGHTMCTYDFYEGQGRLDGALCSFSREKKLDYLKRAFKAGVRNIEMESTVFAAMCGLCGLKAAVVCVTLLDRLDCDQINLPHDVLVEYQQRPQLLISNFIRRRLGLCD-----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VBA0-1", "uniprot_id": "Q9VBA0_DROME", "id": "Q9VBA0-1", "name": "Nucleoside phosphorylase domain-containing protein", "aln": "MPPTITDNQTHDFKAHYDCAHRSSLQDDETDDAYVKRITRYSDGTVKLRNSNIELMDQDILYHLALGSE----SHDLQEMFGDVKFVCMGGTPKRMENFAHFIMNEIGYKLPAGTQLQDISAYSYRYSMYKVGPVLCVSHGMGTPSVSILMHEMIKLMYHAKCKDPVFIRIGTCGGIGVDGGTVIITEDALDGQLRNSHEFTILGKTIHRPAKLDKKLARELKSLASPDDP-YDTIIGKTLCTNDFYEGQGRLDGAFCDFSENEKMAYLEKLRENGVVNIEMESTIFAALTHHAGIKAAVVCVALLNRLNGDQVNAPKEVMNEWQARPQILVSRYIRKVLTHNGQLKALFGHQGSIKSPRRFKLVQQESQAHE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q0E8U4-1", "uniprot_id": "Q0E8U4_DROME", "id": "Q0E8U4-1", "name": "Nucleoside phosphorylase domain-containing protein", "aln": "MS----------------------------------------DKTVELMNPHLETARSDYLYHLDINVANTRDTSELQNRFGDVRVICMGGTGSRMRQLALYLRDILVVSE--SGDPVDLCERGNRYAMYKVGPVLCVSHGVGSSSFSVVLHELIKLLKYARCQDPVLLRIGTCGGLGVPPGTVVASKNAFNGLLRNEHEIAILGQRVVRPAQFSEDVIRDLLAFGVDANDGFQTISANTMGTDCFYEGQGRTDGAICEYSEKDKMEFLQKCHDLGIRNIEMEASMFASVTQKVGVKAGDVCVTLIDRLKGDQITITIDQKHEFEQRPFFVVGRYIKRLLQQ-------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. . * : *. :: .. **** :. : :* *** .:*:**: .**. :* :: . : . : *:. **.*:*.****.:***:* .*.*:::**:***: :*:* * .::****.**:*: *:*: :. *.:. :: .* .**.: : *.:::.:.: :* . *: .:*: * **** * ***:* :*.:.*: :*:: *: *****:::**:: *::*. ***:*::**. **:. . : *:: ** :::..:*:: * ", "identical_positions": 93, "similar_positions": 112, "identity": "24.93%" }, { "cls_id": "homologset.agr.RGD:1308190", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "B5DF89-1", "uniprot_id": "CUL3_RAT", "id": "B5DF89-1", "name": "Cullin-3", "aln": "------------------------------------------------------------------------------------------------------------------------------------------MSNLSKG-----TGSRKDTKMR----------------IRAFPMTMDEKYVNSIWDLLKNAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGEKLYTGLREVVTEHLINKVREDVLNSLNN-NFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQNNVENVYNLGLIIFRDQVVRYGCIRDHLRQTLLDMIARERKGEVVD---RGAIRNACQMLMILGLEGRSVYEEDFEAPFLEMSAEFFQMESQKFLAENSASVYIKKVEARINEEIERVMHCLDKSTEEPIVKVVERELISKHMKTIVEMENSGLVHMLKNGKTEDLACMYKLFSRVPN-GLKTMCECMSSYLREQGKALVSEEGEG---KNPVDYIQGLLDLKSRFDRFLQESFN--------NDRLFKQTIAGDFEYFLNLNSRSP-EYLSLFIDDKLKKG-VKGLTEQEVETILDKAMVLFRFMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFRDMSISNTTMDEFRQHLQATGVSLGGVDLTVRVLTTGYWPTQSATPKCN---IPPAPRHAFEIFRRFYLAKHSGRQLTLQHHMGSADLNATFYG-----PVKKEDGSEVGVGGAQVTGSNTRKHILQVSTFQMTILMLFNNREKYTFEEIQQETDIPERELVRALQSLACGKPTQRVLTK--EPKSKEIESGHIFTVNDQFTSKLHRVKIQTVAAKQGESDPERKETRQKVD---DDRKHEIEAAIVRIMKSRKKMQHNVLVAEVTQQLKARFLPSPVVIKKRIEGLIEREYLARTPEDRKVYTYVA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JLV5-1", "uniprot_id": "CUL3_MOUSE", "id": "Q9JLV5-1", "name": "Cullin-3", "aln": "------------------------------------------------------------------------------------------------------------------------------------------MSNLSKG-----TGSRKDTKMR----------------IRAFPMTMDEKYVNSIWDLLKNAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGEKLYTGLREVVTEHLINKVREDVLNSLNN-NFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQNNVENVYNLGLIIFRDQVVRYGCIRDHLRQTLLDMIARERKGEVVD---RGAIRNACQMLMILGLEGRSVYEEDFEAPFLEMSAEFFQMESQKFLAENSASVYIKKVEARINEEIERVMHCLDKSTEEPIVKVVERELISKHMKTIVEMENSGLVHMLKNGKTEDLACMYKLFSRVPN-GLKTMCECMSCYLREQGKALVSEEGEG---KNPVDYIQGLLDLKSRFDRFLQESFN--------NDRLFKQTIAGDFEYFLNLNSRSP-EYLSLFIDDKLKKG-VKGLTEQEVETILDKAMVLFRFMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFRDMSISNTTMDEFRQHLQATGVSLGGVDLTVRVLTTGYWPTQSATPKCN---IPPAPRHAFEIFRRFYLAKHSGRQLTLQHHMGSADLNATFYG-----PVKKEDGSEVGVGGAQVTGSNTRKHILQVSTFQMTILMLFNNREKYTFEEIQQETDIPERELVRALQSLACGKPTQRVLTK--EPKSKEIESGHIFTVNDQFTSKLHRVKIQTVAAKQGESDPERKETRQKVD---DDRKHEIEAAIVRIMKSRKKMQHNVLVAEVTQQLKARFLPSPVVIKKRIEGLIEREYLARTPEDRKVYTYVA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13618-1", "uniprot_id": "CUL3_HUMAN", "id": "Q13618-1", "name": "Cullin-3", "aln": "------------------------------------------------------------------------------------------------------------------------------------------MSNLSKG-----TGSRKDTKMR----------------IRAFPMTMDEKYVNSIWDLLKNAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGEKLYTGLREVVTEHLINKVREDVLNSLNN-NFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQNNVENVYNLGLIIFRDQVVRYGCIRDHLRQTLLDMIARERKGEVVD---RGAIRNACQMLMILGLEGRSVYEEDFEAPFLEMSAEFFQMESQKFLAENSASVYIKKVEARINEEIERVMHCLDKSTEEPIVKVVERELISKHMKTIVEMENSGLVHMLKNGKTEDLGCMYKLFSRVPN-GLKTMCECMSSYLREQGKALVSEEGEG---KNPVDYIQGLLDLKSRFDRFLLESFN--------NDRLFKQTIAGDFEYFLNLNSRSP-EYLSLFIDDKLKKG-VKGLTEQEVETILDKAMVLFRFMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFRDMSISNTTMDEFRQHLQATGVSLGGVDLTVRVLTTGYWPTQSATPKCN---IPPAPRHAFEIFRRFYLAKHSGRQLTLQHHMGSADLNATFYG-----PVKKEDGSEVGVGGAQVTGSNTRKHILQVSTFQMTILMLFNNREKYTFEEIQQETDIPERELVRALQSLACGKPTQRVLTK--EPKSKEIENGHIFTVNDQFTSKLHRVKIQTVAAKQGESDPERKETRQKVD---DDRKHEIEAAIVRIMKSRKKMQHNVLVAEVTQQLKARFLPSPVVIKKRIEGLIEREYLARTPEDRKVYTYVA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8IP45-1", "uniprot_id": "Q8IP45_DROME", "id": "Q8IP45-1", "name": "", "aln": "MQGRDPRQQQPEPLNNLNANGRYHNRMVAGSNNFNGATVGNVDSAVPCRIARQNVLGQQARSMNINVPNASSMQQHQQSQNRLSAQGLASASRRSYHLAASGGRVRADNRINTNHPLTPTPLSMPVPAPAAPAVVKTETSATTSGPSTSASASAESTEKRFKEIARKYPLWLPEYKRRAFNASMDEKYVETIWASLKNAIQEIQKKNNSGLSFEQLYRNAYNMVLHKHGNRLYYGLREVVSEHLEHKVRADVLEALHS-NFLPKLNQAWTDHQTSMVMIRDILMYMDRVYVQQREVDNVYNLGLILFRDQVVRYSEIQKALREKLLGMVMEERHGEAIN---HLAIKNACSMLITLGINSRTVYEEDFEKPFLAQSAAFYKFESQNFLAENNAGVYIKKVEARITEESSRAALYLDKDTEPRIVRVVEEELIKKHMRPIVEMENSGVVYMIKNSKTEDLACTYKLFSRLKEEGLKVIADTMSAYLREQGRMLVKEEENGN--TNPITFVQNLLDLKDRFDQFLVHSFA--------NDRIFKNVISSDFEHFLNLNNKSP-EYLSLFIDDKLKKG-GKGMSEQEIESILDKTMVLFRFLLEKDVFERYYKTHLAKRLLLNKSVSDDFEKNMISKLKTECGCQFTSKLEGMFKDMSVSNTIMDEFKNFVNNNNLSLGGVELTVRILTTGFWPTQTATPNCN---IPAAPREAFDIFKNFYLNKHSGRQLTLQPQMGTAYINAVFYGRKAVESEKDKDAPSSSSSGCGVP-TTTRKHILQVSTYQMCVLLLFNNRDVLTYDDIHQETDIPERELVRALQSLSMGKPAQRLLVRNSKTKTKDIEPTDEFYVNDAFNSKFHRVKIQTVAAK-GESEPERKETRGKVD---EDRKHEIEAAIVRIMKARKRLAHNLLVSDVTSQLKSRFLPSPVFIKKRIEGLIEREYLQRSPEDRKVYNYLA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53202-1", "uniprot_id": "CUL3_YEAST", "id": "P53202-1", "name": "Cullin-3", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------MITNKKIKIS--------------------VPEKLGLSEESFEESWETVKYAIDHIYSDDMADLSFEQVYKTIYTIVLNKKGPILYNRLKDYLIQKLALLRETIVKDNTHDYEFLGTMARLWEVQCHCFKITGDLMMYMDKVYCKPNRCMEVYDMCLDLFRIEILQK--CSSSLISALISDIERIRNLGSVDSEHTSLWKVLIGMMETLHDNRDSFFLTDFEPVLISATEEYYNKAIDIELLT--PIESLEKIRKLRQFESMLDSSFLNVDSHNKLKTVLENVLIWGKLSDIIEDLTHEAMVISNG---KLLQEIYDLSSEEKY--RVTVIESIKSYINKNAINIPFNEGNRKKGQNAITWSSEIVELYRSQHSFLESIDFGSVRLNNLTGDVSNAILGDVFSMYFSKEGALPSEYLSTYVDHCMKRTKEKDAEIVKIKQDLLDSTKLIGLLTEKDIFEKIYKKQLSRRLLQQRSLV-EIEKWMVQMIKKVLGTFFTSKLEIMLRDISLSSEMYQAFQHSTIN---SIEYLSFAPQVLTRTSWPFQSTNPIDEGISLPPRMSQILAGFEGYYSLKYKERVLKWAHHLSVIEIGCQFNS---------------------------GYYEISFSVYAGVIFLLFEDYEELTLGEIYELTHIPIDDVKSLVMSMST-IPRCKILKK------SSSSGNMKFSVNYFFSSPNRKVKVPVIACPLPSQKSDNLATASSVDTYDNEIVMELSAIIVRIMKTEGKLSHQQLLERTTKRTQSRLSLTPSILKRSIQLLIEKEYIQRNADDPSYYHYLS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : : . :.*: .: * :* **:.* .: :.****::*:. *.:**:*:* ** *:: : ::* . * : :. :** .: : * : .: : *::****:** : .. :**:: * :** :::: . * . *:. : . *: :: : *: * : :.: *** :: : ::: : * . ::*:. * *: .:. : *:*. ** :: *:* . : : :. : * *.* *. .: : :..*:.::. : :* : *.: : . :::* . ** .. : : :.. *. ::. :. * **** ::*. :*: *. ::: * .: *: :: ***:**: ** :*::*** ::*: : ** *:. :*. * ****** *::*:*:*. : *:: *: :.:: ::** ** *::.* : :*. . : *. :* *:. * *. ::. :.. * . : :..*.: :::**:: : * :* : *.** :: : *:: * ::* : .. . * ** *.* ::**: .:*. ....:. * .** :: *:.* ******:. :: *: *: .*.: ::*: :* .:*: *: ***:**: *..:* . * *::", "identical_positions": 163, "similar_positions": 267, "identity": "17.01%" }, { "cls_id": "homologset.agr.RGD:1308191", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZID7-1", "uniprot_id": "D3ZID7_RAT", "id": "D3ZID7-1", "name": "Guanylyl cyclase-activating protein 2", "aln": "MGQQFSWEEAEASGEMDVAELQEWYKKFVVECPSGTLFMHEFKRFFKVTGNEEATQYVEGMFRAFDKNGDNTIDFLEYVAALNLVLRGTLEHKLKWTFKIYDKDRNGCIDRLELLDIVEAIYKLKKACRAELDLEQQGQLLTPEEVVDRIFLLVDENGDGQLSLTEFIEGARRDKWVMKMLQMDVNPGGWITQQRRRSAMF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VBV8-1", "uniprot_id": "GUC1B_MOUSE", "id": "Q8VBV8-1", "name": "Guanylyl cyclase-activating protein 2", "aln": "MGQQLSWEEAEAAGEMDVAELQEWYKKFVVECPSGTLFMHEFKRFFKVTGNEEASQYVESMFRAFDKNGDNTIDFLEYVAALNLVLRGSLEHKLKWTFKIYDKDRNGCIDRLELLDIVEAIYKLKKACRAELDLEHQGQLLTPEEVVDRIFLLVDENGDGQLSLTEFIEGARRDKWVMKMLQMDINPGCWITQQRRRSAMF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UMX6-1", "uniprot_id": "GUC1B_HUMAN", "id": "Q9UMX6-1", "name": "Guanylyl cyclase-activating protein 2", "aln": "MGQEFSWEEAEAAGEIDVAELQEWYKKFVMECPSGTLFMHEFKRFFKVTDDEEASQYVEGMFRAFDKNGDNTIDFLEYVAALNLVLRGTLEHKLKWTFKIYDKDGNGCIDRLELLNIVEGIYQLKKACRRELQTE-QGQLLTPEEVVDRIFLLVDENGDGQLSLNEFVEGARRDKWVMKMLQMDMNPSSWLAQQRRKSAMF", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***::*******:**:*************:*******************.:***:****.****************************:*************** **********:***.**:****** **: * ****************************.**:****************:**. *::****:****", "identical_positions": 175, "similar_positions": 21, "identity": "87.06%" }, { "cls_id": "homologset.agr.RGD:1308193", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R4D1-1", "uniprot_id": "SL9A8_MOUSE", "id": "Q8R4D1-1", "name": "Sodium/hydrogen exchanger 8", "aln": "----------------------------MAEEEFSNTTHETFNFTLHTTLGVTTKLVLPTPAKPILPVQTG-------------------EQAQQEEQSSGMTIFFSLLVLAICIILVHLLIRYRLHFLPESVAVVSLGILMGAVIKVIEFKKLANWKEEEMFRPNMFFLLLLPPIIFESGYSLHKGNFFQNIGSITLFAVFGTAISAFVVGGGIYFLG-QADVISKLNMTDSFAFGSLISAVDPVATIAIFNALHVDPVLNMLVFGESILNDAVSIVLTNTAEGLTRKHMSDVSGWQTFSQALGYFLKMFFGSAALGTLTGLISALVLKHIDLRKTPSLEFGMMIIFAYLPYGLAEGISLSGIMAILFSGIVMSHYTHHNLSPVTQILMQQTLRTVAFLCETCVFAFLGLSIFS-FPHKFEISFVIWCIVLVLFGRAVNIFPLSYLLNFFR------------------DHKITPKMMFIMWFSGLRGAIPYALSLHLGLEPMEKRQLIGTTTIVIVLFTILLLGGSTMPLIRLVDIEDAR------------------ARRRSKKDVN-----LSKTEKMGNAIESEHLSELTEEEYEAHYIRQQDLKGFMWLDAKYLNPFFTRRLTQEDLHHGRIQMKSLTNKWYEEVRQGPSG---SEDDEQELF---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4L208-1", "uniprot_id": "SL9A8_RAT", "id": "Q4L208-1", "name": "Sodium/hydrogen exchanger 8", "aln": "-----------------------------MAEEFSNTTHESFNFTLHTTLGVTTKLVLPTPAEPILPVQTG-------------------EQAQQEEQSSGMTIFFSLLVLAICIILVHLLIRYRLHFLPESVAVVSLGILMGAVIKVIEFKKLANWKEEEMFRPNMFFLLLLPPIIFESGYSLHKGNFFQNIGSITLFAVFGTAISAFVVGGGIYFLG-QADVISKLNMTDSFAFGSLISAVDPVATIAIFNALHVDPVLNMLVFGESILNDAVSIVLTNTAEGLTRKHMSDVSGWQTFSQALGYFLKMFFGSAALGTLTGLISALVLKHIDLRKTPSLEFGMMIIFAYLPYGLAEGISLSGIMAILFSGIVMSHYTHHNLSPVTQILMQQTLRTVAFLCETCVFAFLGLSIFS-FPHKFEISFVIWCIVLVLFGRAVNIFPLSYLLNFFR------------------DHKITPKMMFIMWFSGLRGAIPYALSLHLGLEPMEKRQLIGTTTIIIVLFTILLLGGSTMPLIRLVDIEDAR------------------ARRRSKKDVN-----LSKTEKMGNAIESEHLSELTEEEYEAHYIRQQDLKGFMWLDAKYLNPFFTRRLTQEDLHHGRIQMKSLTNKWYEEVRQGPSG---SEDDEQELF---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y2E8-1", "uniprot_id": "SL9A8_HUMAN", "id": "Q9Y2E8-1", "name": "Sodium/hydrogen exchanger 8", "aln": "-----------------------MGEKMAEEERFPNTTHEGFNVTLHTTLVVTTKLVLPTPGKPILPVQTG-------------------EQAQQEEQSSGMTIFFSLLVLAICIILVHLLIRYRLHFLPESVAVVSLGILMGAVIKIIEFKKLANWKEEEMFRPNMFFLLLLPPIIFESGYSLHKGNFFQNIGSITLFAVFGTAISAFVVGGGIYFLG-QADVISKLNMTDSFAFGSLISAVDPVATIAIFNALHVDPVLNMLVFGESILNDAVSIVLTNTAEGLTRKNMSDVSGWQTFLQALDYFLKMFFGSAALGTLTGLISALVLKHIDLRKTPSLEFGMMIIFAYLPYGLAEGISLSGIMAILFSGIVMSHYTHHNLSPVTQILMQQTLRTVAFLCETCVFAFLGLSIFS-FPHKFEISFVIWCIVLVLFGRAVNIFPLSYLLNFFR------------------DHKITPKMMFIMWFSGLRGAIPYALSLHLDLEPMEKRQLIGTTTIVIVLFTILLLGGSTMPLIRLMDIEDAK------------------AHRRNKKDVN-----LSKTEKMGNTVESEHLSELTEEEYEAHYIRRQDLKGFVWLDAKYLNPFFTRRLTQEDLHHGRIQMKTLTNKWYEEVRQGPSG---SEDDEQELL---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VPJ1-1", "uniprot_id": "Q9VPJ1_DROME", "id": "Q9VPJ1-1", "name": "Sodium/hydrogen exchanger", "aln": "MRVWVAYSAAALLLLVHAGPESISGQEVPQSKTSSNTTTTDNSSSIHTVSDVFVNSPLGNVTPSISASGNASTTKRGNASTLVTDPPLIDSHAVEQEHNSSLSLFFVICVIMLGILLIHSMLQTGFQYLPESIVVVFLGAFIGLSLNVMSGQNGS-WKREEVFSPMGFFLVLLPPIIFESGYNLHKGNFFQNIGSILVFAIFGTTISALVIGAGIYLLG-LGEVAFRLSFSESFAFGSLISAVDPVATVAIFHALDVDPILNMLVFGESILNDAISIVLTASITQSANVNAEASTGEAMFS-ALKTFCAMFFASAGIGVIFALISALLLKHIDLRKHPSLEFAMMLMFTYAPYVLAEGIHLSGIMAILFCGIVMSHYTHFNLSTVTQITMQQTMRTLAFIAETCVFAYLGLAIFS-FKHQVELSFVIWAIVLCLIGRACNIFPLAFLVNKFR------------------EHKINNKMQFIMWFSGLRGAISYALSLHLNLDSQEKRHVIITTTLIIVLFTTLVLGGSTMPLLKYLKPGKKRRARGSGRNAAEEGGRRNGSGRKRSKSIS-----LSKTREWGQAIDSEHLSELTEEE-DVTFTQARDR--FGRMDRKYFIPFFTRRFNSQELHECKSQMADLTNKWYQAIRVSPLD---SDESDEEIGLAASTSQIHLTRS--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04121-1", "uniprot_id": "NHX1_YEAST", "id": "Q04121-1", "name": "Endosomal/prevacuolar sodium/hydrogen exchanger", "aln": "----------------------MLSKVLLNIAFKVLLTTAKRAVDPDDDDELLPSPDLPGSDDPIAGDPDVD------------------LNPVTEEMFSSWALFIMLLLLISALWSSYYLTQKRIRAVHETVLSIFYGMVIGLIIRMSPG---HYIQDTVTFNSSYFFNVLLPPIILNSGYELNQVNFFNNMLSILIFAIPGTFISAVVIGIILYIWTFLGLESIDISFADAMSVGATLSATDPVTILSIFNAYKVDPKLYTIIFGESLLNDAISIVMFETCQKFHGQPATFSS----VFEGAGLFLMTFSVSLLIGVLIGILVALLLKHTHIRRYPQIESCLILLIAYESYFFSNGCHMSGIVSLLFCGITLKHYAYYNMSRRSQITIKYIFQLLARLSENFIFIYLGLELFTEVELVYKPLLIIVAAISICVARWCAVFPLSQFVNWIYRVKTIRSMSGITGENISVPDEIPYNYQMMTFWAGLRGAVGVALALGIQG---EYKFTLLATVLVVVVLTVIIFGGTTAGMLEVLNIKTGCISEEDTSDDEFDIEAPRAINLLNGSSIQTDLGPYSDNNSPDISIDQFAVSSNKNLPNNISTTGGNTFGGLNETENTSPNPARSS-MDKRNLRDKLGTIFNSDSQWFQNFDEQVLKPVFLDNVSPSLQDSATQSPADFSSQNH", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . : . * .* :. :* *. ::*: : :: : : : : :: : *:: : * .:* :.: : * . ** :******::***.*:: ***:*: ** :**: ** ***.*:* :*: . :.::::::.*: :**.***: ::**:* .*** * ::****:****:***: : : . . * * * :*.: .:: **:*** .:*: *.:* ::::::* .* :::* :***:::**.**.:.**::.*:* :** :: :: :* :.*. :* :*** :*: . : ::* . : ..* :***: ::* : .:* : :: :::*****: **:* : * : : :*.:::*::* :::**:* ::. :. ..:. *.... . :::. :*. .: : . : : . * : : ..:*:. : .:*:: . :: . .: ", "identical_positions": 124, "similar_positions": 201, "identity": "18.13%" }, { "cls_id": "homologset.agr.RGD:1308194", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LVJ1-1", "uniprot_id": "A0ABK0LVJ1_RAT", "id": "A0ABK0LVJ1-1", "name": "", "aln": "---------------------------------------------------------------------------------MEAFPWAPRSPRRA---------------RAPAPMALVPSARYVSASGPVHPQPFSYWNDYLGLATLITRASD----------RG-----------------SPHEGPGPTPAGPTLGPP--EDDEDDDGDEPEAGGRYLGGALELRALELCAGPAEAGLLEERFAELNPFAGRAAAVLLGCAPSAS----AASTAEVTPREEPSPAWAAEPRLHATSGAT-----AARLLKPELQVCVFCRNNKEAVALYTTHILKGPDGRVLCPVLRRYTCPLCGASGDNAHTIKYCP---LSKVPPPTVRPPPRSTRDNLPSKKLR-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80WY3-1", "uniprot_id": "NANO1_MOUSE", "id": "Q80WY3-1", "name": "Nanos homolog 1", "aln": "---------------------------------------------------------------------------------MEAFPWAPRSPRRA---------------RAPAPMALVPSARYVSASGPVHPQPFSSWNDYLGLATLITRASD----------RG-----------------SPHEGPGPTAAGPTMGPP--EDDEDDDGEEPEAGGRYLGGALELRALELCAGPAEPGLLEERFAELNPFAGRAAAVLLGCAPTASTTAAAASTAEVTPREEPSPAWAAEPRLHAASGAT-----AARLLKPELQVCVFCRNNKEAVALYTTHILKGPDGRVLCPVLRRYTCPLCGASGDNAHTIKYCP---LSKVPPPTVRPPPRSNRDSLPSKKLR-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WY41-1", "uniprot_id": "NANO1_HUMAN", "id": "Q8WY41-1", "name": "Nanos homolog 1", "aln": "---------------------------------------------------------------------------------MEAFPWAPRSPRRG---------------RAPPPMALVPSARYVSAPGPAHPQPFSSWNDYLGLATLITKAVDGEPR--FGCARGGNGGGGSPPSSSSSSCCSPHTGAGPGALGPALGPPDYDEDDDDDSDEPGSRGRYLGSALELRALELCAGPAEAGLLEERFAELSPFAGRAAAVLLGCAPAAA--AAATTTSEATPREERAPAWAAEPRLHAASGAA-----AARLLKPELQVCVFCRNNKEAMALYTTHILKGPDGRVLCPVLRRYTCPLCGASGDNAHTIKYCP---LSKVPPPPARPPPRSARDGPPGKKLR-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FDB3-1", "uniprot_id": "NANO1_DANRE", "id": "E7FDB3-1", "name": "Nanos homolog 1", "aln": "-------------------------------------------------------------------------------------------------------------------MDFLNHN-YLSAR-ASYDYTFNFWNDYLGLSTLVTKNSK------------------------------HSVPQNPNSITESLKAT---LGLDDSPPCPCVMGEGDSGGHLDSCCCPPPASISILDLKERFSILSPFQNQNQGSLLSSSQERE--------IGIGGGFAGFDLFGVERKMRKP----------AARNKQEPKICVFCRNNGAPEEVYGSHVLKTPDGRVVCPILRAYTCPLCSANGDNAHTIKYCP---LSKDQPAQRVLKGGRAVGGKRVKIF--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P25724-1", "uniprot_id": "NANOS_DROME", "id": "P25724-1", "name": "Protein nanos", "aln": "MFRSNLEGSGAAAVGVANPPSLAQSGKIFQLQDNFSAFHARGGLNILGLQDMYLDTSGANSSATLSPPITPVTPDPSTSAQSTHFPFLADSAATANSLLMQRQYHYHLLLQQQQQLAMAQHQLALAASAAAASASHQQTDEIARSLKIFAQVTTGAAENAAGSMQDVMQEFATNGYASDDLGRMSYGSAPPQVQMPPQQQHQQQQGLHLPLGRNPAQLQTNGGNLMPIPLATHWLNNYREHLNNVWRNMSYIPAAPNTMGLQAQTAATVSTNLGVGMGLGLPVQGEQLRGASNSSNNNNNNNKVYKRYNSKAKEISRHCVFCENNNEPEAVINSHSVRDNFNRVLCPKLRTYVCPICGASGDSAHTIKYCPKKPIITMEDAIKAESFRLAKSSYYKQQMKV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : ::* . ... :: .:.:: * . . . . .. *:: : :. : * . ... . * : ****.** . : :* :: .**:** ** *.**:*.*.**.******** : . . .. : : ", "identical_positions": 33, "similar_positions": 53, "identity": "8.23%" }, { "cls_id": "homologset.agr.RGD:1308195", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P0DP59-1", "uniprot_id": "SLUR2_MOUSE", "id": "P0DP59-1", "name": "Secreted Ly-6/uPAR domain-containing protein 2", "aln": "MRLPFWFLLAVVLSMELAVTQGLQCHLCKGFGGCSRPSSCPWSSTHCVIIATRSPISFTDLPLVTKMCYSGCPDVSSLGLGPHVSIACCQSNLCNRD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZUR5-1", "uniprot_id": "D3ZUR5_RAT", "id": "D3ZUR5-1", "name": "Secreted Ly-6/uPAR domain-containing protein 2", "aln": "MRLLFWFLLAVVLSMELAVTQGMFCHLCKGFGGCSHPFRCPGNTTHCVIIATRSPISFTDLPLVTKMCYNTCPDVPSLGLGPHVSIVCCQSNLCNRD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0DP57-1", "uniprot_id": "SLUR2_HUMAN", "id": "P0DP57-1", "name": "Secreted Ly-6/uPAR domain-containing protein 2", "aln": "MQLGTGLLLAAVLSLQLAAAEAIWCHQCTGFGGCSHGSRCLRDSTHCVTTATRVLSNTEDLPLVTKMCHIGCPDIPSLGLGPYVSIACCQTSLCNHD", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:* :***.***::**.::.: ** *.******: * .:**** *** . *********: ***:.******:***.***:.***:*", "identical_positions": 55, "similar_positions": 23, "identity": "56.7%" }, { "cls_id": "homologset.agr.RGD:1308196", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P0C2C1-1", "uniprot_id": "RM30_RAT", "id": "P0C2C1-1", "name": "Large ribosomal subunit protein uL30m", "aln": "-MAGVLRSVFQRPPGRLQTVKKGAESLIGTEWIRHKFTRSRIPDKVFQPRPEDHEKYGGDPQNPHKLHIVTRIRSTKRRPYWEKDTIKMLGLQKAHS-PQIHKNIPSVNAKLKVVKHLIRIQPLKLPQGLPTEETMSSTCLKSTGELVVQWHLKPVEQEAKS----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D7N6-1", "uniprot_id": "RM30_MOUSE", "id": "Q9D7N6-1", "name": "Large ribosomal subunit protein uL30m", "aln": "-MAGVLRSAFPRPPCRLQTVKKGAESLIGTEWIRHKFTKSRIPDKVFQPKPEDHEKYGGDPQNPHKLHIVTRIRSTKRRPYWEKDTIKMLGLQKAHS-PQIHKNIPSVNAKLKVVKHLIRIQPLKLPQGLPTEETMSSTCLKSTGELVVQWHLKPVEQEAKS----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TCC3-1", "uniprot_id": "RM30_HUMAN", "id": "Q8TCC3-1", "name": "Large ribosomal subunit protein uL30m", "aln": "-MAGILRLVVQWPPGRLQTVTKGVESLICTDWIRHKFTRSRIPEKVFQASPEDHEKYGGDPQNPHKLHIVTRIKSTRRRPYWEKDIIKMLGLEKAHT-PQVHKNIPSVNAKLKVVKHLIRIKPLKLPQGLPAEENMSNTCLKSTGELVVQWHLKPVEQKAHES---------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W4I3-1", "uniprot_id": "Q9W4I3_DROME", "id": "Q9W4I3-1", "name": "Large ribosomal subunit protein uL30m", "aln": "MNLGRLLNPLRSTACSVRSYGKHNKKFLYKNGQ-------KFEGITYYPRTPDHQDP---PVEPAKLFRVQRIKPLKGNPYWENRILKDLGLDGKQSDFTVVKNIPENNARLWKIKHLIKVTPVTFPYGEPTAQDVRHTILKENGECLVTKDLGPIDTRLAARQDYDEQPKRLDTDLLRKDARLKWLNPW", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * . .. ::: * :.:: .: :: .: . . **:. * :* **. * **:. : .****: :* ***: :: : ****. **:* :****:: *:.:* * *: : : * **..** :* .* *:: . ", "identical_positions": 43, "similar_positions": 50, "identity": "22.63%" }, { "cls_id": "homologset.agr.RGD:1308197", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZX30-1", "uniprot_id": "D3ZX30_RAT", "id": "D3ZX30-1", "name": "", "aln": "MHPTGTMDVGFTRSAVQTLSRSHCKNIKQKISQWEGRANGVTQPAKFHPKDFGVRYNNCHQERPPHKHPTGEER----------NGGLPRNTDARSHDQSEGESESRELKDPHPLEGEPNSSRMCARVKQIESCQAVAVDPEASLPPGNFYTSQIPWKSIEGLTPNKVFTVALSPCDFTEEEPELSVLDSSYRVAKSLENIYCEPEGQECGPSINPLPKPRRTFRYLSESDGMPYKERNCDQKNCESVCCADSSLASFQDPEPKRYGGKIRGRSKRKSFEFEDIQHFRN--SRKIHEELERNAGSALYYTQSEDNIYEDIIYPAKENPYEDIPVQSFPIWRSPSAWRLPPAKSAFRTPKLPPKPQFLQRKTMELKNTQAYLRSKLTKDTTLPVTLTEWKLFRAGEVANRKKRNLPRLVLKINDTFESKRGKKRVKLQPYTGKEAPSSKGETSGNESDAEYLPKNRHKRLAQLQQSSKRSPHYQTLERDLIELQEQQLFELFVVVSLQKKASGMEYMPRVIQQFPSKGDHGYKQSKDTEERLKVIPRFCFPDSEDCAPTLELKSETFSFVLTGEDGSRWFGYCKKLLPEGRGKRLPEVYCMVSRLGCFNLFSKILDEVEKRREMSPALVYPFMRSVMEAPFPAPGRTITVKSYLPGAGDESIELCRPLDSRLEHVDFECLFKCLSVRHLIRVCASLLLERRVIFVADSLSTLSKCGHAVVATLYPFTWQHTYIPVLPVSMIDIVCSPTPFFIGILSCSLPLLQDLPIEEVLIVDLCADKFLQEVSDEDEIMPPKLQAALVQILEERDEVLAQERQFSQDVTLNSLVSEAFVRFFVELVGHYSLNMTVTERGERVFLREPFRKSHTSRSVRHFLDLFMETQMFAGFVQDRELRQSGVKGLFEVRALQYLETIPESEPSGVNRILRSLGSKMRFLHKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P9P8-1", "uniprot_id": "DEN2C_MOUSE", "id": "Q6P9P8-1", "name": "DENN domain-containing protein 2C", "aln": "------MDVGFTRSAVQTLSRSHCKNIKQKISQWEGRANGVTKTAKFHPKDFGVRYN-CHQESPPHKRPTGEER----------NGALPRNTDVKSRDQSEDEGEGGECRGSHPSEAGLDSSLVCARVKQIEGCQAVAVGPEASLPPGNFYTSQIPWRSIDGLSPDKPLNLALAPCNSTGREPDLSVLDSSYGITKSLENIYYEPEGQECGPSINPLPKPRRTFRYLSESDGIPYKERNCDQKYCESISCVDPSLASSQDPEPKKYGGKIRGRSKRKSFEFEDIQHFRN--SRKIHEELGRNAGSALYYTQSEDNIYEDIIYPAKENPYEDIPVQSFPVWRSPSAWRLPPAKSAFRTPKLPPKPQFFQRKTMELKNSQAYFRSKITKDTTLPVTLTEWKLFRAGEVANKKKRNLPPLVLKINDTFESKRGKKRVKLQPYTGKEAPSSKGETSGNESDAEYLPKNRHKRLAQLQPSSKRNPHYQTLERDLIELQEQQLFELFVVVSLQKKPAG--YTPQVIQQFPSKGDHGYKQSKDTEERLKVIPRFCFPDSEDSAPTLELKSETFSFVLTGEDGSRWFGYCKKLLPEGRGKRLPEVYCMVSRLGCFNLFSKILDEVEKRREMSPALVYPFMRSVMEAPFPAPGRTITVKSYLPGAGDESIELCRPLDSRLEHVDFECLFKCLSVRHLIRVCASLLLERRVIFVANSLSTLSKCGHAVVATLYPFTWQHTYIPVLPVSMIDIVCSPTPFFIGILSCSLPHLQDLPIEEVLIVDLCADRFLQEVSDEDEILPPKLQAALVQILEDRDEVLAQEQQFSQEVTLSSLVSEAFVRFFVELVGHYSLNMTVTERGERVFQREPFRKSHTSRSVRHFLDLFMETQMFAGFVQDRELRQSGVKGLFEVRALQYLETIPESEPSGVNRILRSLGSKMKFLHKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q68D51-1", "uniprot_id": "DEN2C_HUMAN", "id": "Q68D51-1", "name": "DENN domain-containing protein 2C", "aln": "------MDVGFSRTTVQTLSRSHCKNIKQKISQWEGRANGISNPEKWCPKDFGVRYN-CHQEIRLKKNPIAERKSKNLDVTSRENVGLDINENTKSHDQSENENKKHEYDDTHFFKNESESNWVCSRVKEIESCKEDVLDPETSLPPGNFYTSQILWKKIEALPPDKLLNLALEHCDSSEKELNFRVLDSSYGITKSLENIYSEPEGQECGPSINPLPKPRRTFRYLSESGVTPYKERNCDKKYCENNSCAQSSLASSQEPEPKKYGGKIRGRSKRKSFEFEDIQHFRNRNSQTIREELGRNSGSALYYTQSEDNIYEDIIYPTKENPYEDIPVQPLPMWRSPSAWKLPPAKSAFKAPKLPPKPQFLHRKTMEVKNSQAYLRSKLTKDTTLPVTLTEWKLFRAGEVANTKRKNLPRLVLKIDDIFESKRGKKKVKLHSYTGKELPPTKGETSGNESDAEYLPKNRHKRLAQLQPSSKRNPHYQTLERDLIELQEQQLFELFVVVSLQKKPSGISYIPQVIQQFPGKDDHGYKQSKDMEERLKVIPKFCFPDSKDWMPTSELKSETFSFVLTGEDGSRWFGYCKKLLPVGKGKRLPEVYCMVSRLGCFNLFSKILDEVEKRREMSPALVYPFMRSVMEAPFPAPGRTITVKSYLPGAGDESIELCRPLDSRLEHVDFKCLFKCLSVCHLIRVCASLLLERRVIFVANSLSTLSKCGHAVVATLYPFTWQHTYIPVLPASMIDIVCSPTPFLIGILSCSLPQLQDLPIEEVLIVDLCADKFLQEVSDEDEILPPKLQAALMQILEERNEILTQEQNFSQDVTLNSLVSEAFVRFFVELVGHYSLNMTVTERGERVFQREPFRKSHTSRSVRHFLDLFMETQMFAGFIQDRELRKSGVKGLFEIRAIQYLETIPESEPSGMNRILRSLGSKMKFLQKK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *****:*::*************************:::. *: ********* **** :*.* .*.: * .* * :.:*:****.*.: * ..* : :*. :*:***:**.*: .:.**:************ *:.*:.*.*:* :.:** *: : .* :: ****** ::******* ***************************. ********:* **. .*.:.**** *:****:************************ *:.*:*** **:********************:***********.:*:*******:********::*********::*****:**:***:***:*********************** *::*** *****:* ********:***:.***** *.:************************** ****.******************************.:* * *:******.*.********* ********:******:* ** **************************** *:**************************************************************************************:******** *******************:******************************.************:********* *****************:***********:********:****:*:*:*:**::***:***.******************************** *****************************:******:********:**:*************:***********:**:**", "identical_positions": 746, "similar_positions": 116, "identity": "79.79%" }, { "cls_id": "homologset.agr.RGD:1308198", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZLB7-1", "uniprot_id": "FOSB_RAT", "id": "D3ZLB7-1", "name": "Protein FosB", "aln": "MFQAFPGDYDSGSRCSSSPSAESQYLSSVDSFGSPPTAAASQECAGLGEMPGSFVPTVTAITTSQDLQWLVQPTLISSMAQSQGQPLASQPPAVDPYDMPGTSYSTPGLSAYSTGGASGSGGPSTSTSTSGPVSARPARARPRRPREETLTPEEEEKRRVRRERNKLAAAKCRNRRRELTDRLQAETDQLEEEKAELESEIAELQKEKERLEFVLVAHKPGCKIPYEEGPGPGPLAEVRDLPGSTSAKEDGFGWLLPPPPPPPLPFQSSRDAPPNLTASLFTHSEVQVLGDPFPVVSPSYTSSFVLTCPEVSAFAGSQRTSGSEQPSDPLNSPSLLAL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P13346-1", "uniprot_id": "FOSB_MOUSE", "id": "P13346-1", "name": "Protein FosB", "aln": "MFQAFPGDYDSGSRCSSSPSAESQYLSSVDSFGSPPTAAASQECAGLGEMPGSFVPTVTAITTSQDLQWLVQPTLISSMAQSQGQPLASQPPAVDPYDMPGTSYSTPGLSAYSTGGASGSGGPSTSTTTSGPVSARPARARPRRPREETLTPEEEEKRRVRRERNKLAAAKCRNRRRELTDRLQAETDQLEEEKAELESEIAELQKEKERLEFVLVAHKPGCKIPYEEGPGPGPLAEVRDLPGSTSAKEDGFGWLLPPPPPPPLPFQSSRDAPPNLTASLFTHSEVQVLGDPFPVVSPSYTSSFVLTCPEVSAFAGAQRTSGSEQPSDPLNSPSLLAL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P53539-1", "uniprot_id": "FOSB_HUMAN", "id": "P53539-1", "name": "Protein FosB", "aln": "MFQAFPGDYDSGSRCSSSPSAESQYLSSVDSFGSPPTAAASQECAGLGEMPGSFVPTVTAITTSQDLQWLVQPTLISSMAQSQGQPLASQPPVVDPYDMPGTSYSTPGMSGYSSGGASGSGGPSTSGTTSGPGPARPARARPRRPREETLTPEEEEKRRVRRERNKLAAAKCRNRRRELTDRLQAETDQLEEEKAELESEIAELQKEKERLEFVLVAHKPGCKIPYEEGPGPGPLAEVRDLPGSAPAKEDGFSWLLPPPPPPPLPFQTSQDAPPNLTASLFTHSEVQVLGDPFPVVNPSYTSSFVLTCPEVSAFAGAQRTSGSDQPSDPLNSPSLLAL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "********************************************************************************************.***************:*.**:************ :**** .**************************************************************************************************************:.******.**************:*:**************************.*******************:******:**************", "identical_positions": 322, "similar_positions": 14, "identity": "95.27%" }, { "cls_id": "homologset.agr.RGD:1308199", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L1R9-1", "uniprot_id": "A0ABK0L1R9_RAT", "id": "A0ABK0L1R9-1", "name": "Mitogen-activated protein kinase kinase kinase kinase", "aln": "----------MALLRDVSLQDPRDRFELLQRVGAGTYGDVYKARDTVTSELAAVKIVKLDPGDDISSLQQEITILRECRHPNVVAYIGSYLRNDRLWICMEFCGGGSLQEIYHATGPLEERQIAYVCREALKGLHHLHSQGKIHRDIKGANLLLTLQGDVKLADFGVSGELTASVAKRRSFIGTPYWMAPEVAAVERKGGYNELCDVWALGITAIELGELQPPLFHLHPMRALMLMSKSSFQPPKLRDKTRWTQTFHHFLKLALTKNPKKRPTAEKLLQHPFTTQPLPPALLTQLLDKASDP--------------------------------------------------HLGTLSPE------------DSELETHDMFP-----------------------------------------------------DTIHSRGHHGPAERTPSEIQFHQVKFGAPRRKETDPLSEPWEEEWTFLGKEELSRSLLQSVQEALEERS-----------LTIR-----------------PAIELQELDSPDD----------------------------------------------------------------------------------------------------------------------------AIGTIKRAPFMGLPHTESTSDDNAQSCSPGTLS---------------------------------APPAGPSSP-----------------------------PLLP-------------------------------------TAWATLKQREDHERSSCHGLPPTPKVHMGACFSKVFNGCPLQIHAAVTWVHPVTRDQFLVVGAEEGIYTLNLHELHEDTLEKLISHRCIWLYCVNNVLLSLSGKSTHIWAHDLPGLFEQRRLQHQAPLSIPTNRITQRIIPRRFALSTKIPDTKGCLQCRVVRNPYTGSTFLLAALPASLLLLQWYEPLQKFLLLKNFSSPLPSPAG------------MLEPLVLDGKELPQVCVGAEGPEG---------PGCRVLFHVLPLETGLTPDILIPPG-----------------------CVRIVNLQGEP--TAALAPELTFDFPIETVVCLQDSVLAFWSHGMQGRSLDTNEVTQEITDETRIFRVLGAHRDIILES--IPTGNPGAHS--NLYILTGHQSSY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61161-1", "uniprot_id": "M4K2_MOUSE", "id": "Q61161-1", "name": "Mitogen-activated protein kinase kinase kinase kinase 2", "aln": "----------MALLRDVSLQDPRDRFELLQRVGAGTYGDVYKARDTVTSELAAVKIVKLDPGDDISSLQQEITILRECRHPNVVAYIGSYLRNDRLWICMEFCGGGSLQEIYHATGPLEERQIAYVCREALKGLHHLHSQGKIHRDIKGANLLLTLQGDVKLADFGVSGELTASVAKRRSFIGTPYWMAPEVAAVERKGGYNELCDVWALGITAIELGELQPPLFHLHPMRALMLMSKSSFQPPKLRDKTRWTQNFHHFLKLALTKNPKKRPTAERLLQHPFTTQHLPPALLTQLLDKASDP--------------------------------------------------HLGTLSPE------------DSELETHDMFP-----------------------------------------------------DTIHSRSHHGPAERTPSEIQFHQVKFGAPRRKETDPLNEPWEEEWTLLGKEELSGSLLQSVQEALEERS-----------LTIR-----------------PALELQELDSPDD----------------------------------------------------------------------------------------------------------------------------AIGTIKRAPFLGLPHTESTSGDNAQSCSPGTLS---------------------------------APPAGPGSP-----------------------------ALLP-------------------------------------TAWATLKQQEDRERSSCHGLPPTPKVHMGACFSKVFNGCPLQIHAAVTWVHPVTRDQFLVVGAEEGIYTLNLHELHEDTMEKLISQRCSWLYCVNNVLLSLSGKSTHIWAHDLPGLFEQRRLQHQAPLSIPTNRITQRIIPRRFALSTKIPDTKGCLQCRVVRNPYTGSTFLLAALPASLLLLQWYEPLQKFLLLKNFSSPLPSPAG------------MLEPLVLDGKELPQVCVGAEGPEG---------PGCRVLFHVLPLEAGLTPDILIPPEGIPGSAQQVIQVDRDTVLVSFERCVRIVNLQGEP--TAALAPELTFDFTIETVVCLQDSVLAFWSHGMQGRSLDTNEVTQEITDETRIFRVLGAHRDIILES--IPTDNPGAHS--NLYILTGHQSSY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q12851-1", "uniprot_id": "M4K2_HUMAN", "id": "Q12851-1", "name": "Mitogen-activated protein kinase kinase kinase kinase 2", "aln": "----------MALLRDVSLQDPRDRFELLQRVGAGTYGDVYKARDTVTSELAAVKIVKLDPGDDISSLQQEITILRECRHPNVVAYIGSYLRNDRLWICMEFCGGGSLQEIYHATGPLEERQIAYVCREALKGLHHLHSQGKIHRDIKGANLLLTLQGDVKLADFGVSGELTASVAKRRSFIGTPYWMAPEVAAVERKGGYNELCDVWALGITAIELGELQPPLFHLHPMRALMLMSKSSFQPPKLRDKTRWTQNFHHFLKLALTKNPKKRPTAEKLLQHPFTTQQLPRALLTQLLDKASDP--------------------------------------------------HLGTPSPE------------DCELETYDMFP-----------------------------------------------------DTIHSRGQHGPAERTPSEIQFHQVKFGAPRRKETDPLNEPWEEEWTLLGKEELSGSLLQSVQEALEERS-----------LTIR-----------------SASEFQELDSPDD----------------------------------------------------------------------------------------------------------------------------TMGTIKRAPFLGPLPTDPP-AEEPLSSPPGTLP---------------------------------PPPSGPNSS-----------------------------PLLP-------------------------------------TAWATMKQREDPERSSCHGLPPTPKVHMGACFSKVFNGCPLRIHAAVTWIHPVTRDQFLVVGAEEGIYTLNLHELHEDTLEKLISHRCSWLYCVNNVLLSLSGKSTHIWAHDLPGLFEQRRLQQQVPLSIPTNRLTQRIIPRRFALSTKIPDTKGCLQCRVVRNPYTGATFLLAALPTSLLLLQWYEPLQKFLLLKNFSSPLPSPAG------------MLEPLVLDGKELPQVCVGAEGPEG---------PGCRVLFHVLPLEAGLTPDILIPPEGIPGSAQQVIQVDRDTILVSFERCVRIVNMQGEP--TATLAPELTFDFPIETVVCLQDSVLAFWSHGMQGRSLDTNEVTQEITDETRIFRVLGAHRDIILES--IPTDNPEAHS--NLYILTGHQSTY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1ZBH7-1", "uniprot_id": "A1ZBH7_DROME", "id": "A1ZBH7-1", "name": "non-specific serine/threonine protein kinase", "aln": "MAAAHSHHNANMLSSDISRRNPQDEYELIQKIGSGTYGDVYKAKRIQSNELAAIKVIKLEPSDDIQIIQQEIIMMRDCRHPNIIAYYGSYLRRDKLWICMEFCGGGSLQDIYQVTGPLTEVQIAYMCRETLKGLEYLHSMGKMHRDIKGANILLTEYGDVKLADFGVSAQITATINKRKSFIGTPYWMAPEVAAVERKGGYNQLCDIWACGITAIELAELQPPMFDLHPMRALFLMSKSGFKPPTLNNKDKWSPTFHNFIKTALTKNPKKRPTAERLLQHPFVQCEMSLRVAKELLQKYQSPNPQFYYYLDGDEESVAGVPQRIASKMTSRTNGVPAQNHTLKTGMTTNSTWNERSSSPETLPSDMSLLQYIDEELKLRATLPLNNDTKDPLGAECSCSSHNGGAAGGGGGGGVGVGAGGAAANGSSSSSGGATVGTTHHQHQQHHQHHHHPNHLHQHQSHQLPQQQQQQSHQAAQQEHHHHHPMTSSISSGLVTANANNISSSASLASMPGLSAYLGMRSHVVGHMGMGFGMGLGMSNLRTTSIDADDDELVAADVAMNNAAAAVPGNGSGAGNGSGSGCSASAAHYLRYSSNYRSAAAAQASQAAHPHVNSNSNSNNGHGHAPITSSISSSASSASFYNRLLLLDNSSGDAVVGGNGGGSSNISSSGGASSGTNGLLDKHELDALPQAATKSAGDGFSHSNSPTANSGAGATGSRDNDGPSSSNSSHLYQNLLRSSSGETPAGSSSAGNNCDYRHENNQNGLEDSPRRHSSMDQLIGLLENMGKSPRTRSLSDGGTQDDDEAEKEAQPDLLNNTPPVPPKRSHKRRHTPPRPISNGLPPTPKVHMGACFSKIFNGCPLRVHCTASWIHPETRDQHLLIGAEEGIYNLNMNELHDAAIDQLFPRRTTWLYVIKDVLMSLSGKSCQLYRHDLVALHS----KQTVRFSLHMNKIPERLVPRKFALTTKVPDTKCCTQCCVTRNPYNGYKYLCGATPSGIFLMQWYDPLNKFMLLKQCEWPAISIQGGGHGCVQNGHTPVFEMIITPELEYPIVCTGVRKAMNGCLKLELINMNSASWFHSEDLEYDAMATMVPRRD--LLKVVRVHQVEKDAILVCYGNLIQVVTLQGNPKQHKKMVSQLNFDFNVDSIVCLPDSVLAFHKHGMQGKSLRNGEVTQEIKDMSRTYRLLGSDKVVALESQLLRTGSLGSEEGHDLYILAGHEASY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *:* ::*:*.:**:*::*:*********: :.****:*::**:*.***. :**** ::*:*****::** *****.*:**************:**:.**** * ****:***:****.:*** **:********:*** ***********.::**:: **:***********************:***:** *******.*****:*.*******:*****.*:**.*.:* :*: .**:*:* *************:******. :. : .:**:* ..* : : *** * **: :* * *.: :* .: *..:: ** : . :::: . *.. ...:* .*: : : :.. : * :* . . .:*: ** : * :.: : . : . : * . .. . .*:*..*. ** .. : *::. *. .:****************:******::*.:.:*:** ****.*::*******.**::***: ::::*:.:* *** :::**:****** ::: *** .*.. :: . :*: *::.:*::**:***:**:**** * ** *.****.* .:* .* *:.::*:***:**:**:***: . * * * ::* :: * * **.*.. . . .. ** ** . . :: :::*.:**:* :..:*.*** ::::*** ****** .*****:** ..******.* :* :*:**:.: : *** : *.. :.. :****:**:::*", "identical_positions": 382, "similar_positions": 249, "identity": "31.21%" }, { "cls_id": "homologset.agr.RGD:1308200", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "M0RDK4-1", "uniprot_id": "M0RDK4_RAT", "id": "M0RDK4-1", "name": "Membrane-associated phosphatidylinositol transfer protein 3", "aln": "MAKAGSAGGPSPG---GGAPWHLRNVLSDSVESSDDEFFDAREEVAEGKNAILIGMSQWSSNDLVEQIETMGKLDEHQGEGATACTSSILQEKQRELYRVSLRRQKFPAQGSIEIHEDVEEGCSQRSCKTHVLLLVLHGGNVLDTGSGDPSCKAADIHTFSSVLEKVTRAHFPAALGHILIKFVPCPAICSEAFSLVSNLNPYSHDEGCLSTSQDHVPLAALPLLAISSPQYQDAVATVIERANHIYGEFLKSSDGIGFNGQVCLIGDCVGGLLAFDAICYSAGPSGDSPGSSSRKGSISSTQDTP-VVVEEDCNLASSKRLSKSNIDVSSGVEDED-PKRPLTRKQSDSSTYDCEAITQHHAFLSSIHSSVLKDEAEAPAAGTPQLSEVSLGRFDFDVSDFFLFGSPLGLVLAMRRTVLPGIDGFQMRPACSQVYSFFHCADPSASRLEPLLEPKFHLVPPVSVPRYQRFPLGDGQSLLLADALHTHSPLFLEGSSRGSPPLLDAPASPPQAPRSQRPERRLSEGSSHSDSSESSDSLAPMGASRITAKWWGTKRIDYALYCPDVLTAFPTVALPHLFHASYWESTDVVAFILRQVMRYESASVKESTGLDPTALSPANPREKWLRKRTQVKLRNVTANHRANDVIAAEDGPQVLVGRFMYGPLDMVALTGEKVDILVMTEPSSGRWVHLDTEITNNSGRITYNVPRPRRLGVGVYPVKMVVRGDQTCAMSYLTVLPRGMECVVFSIDGSFAASVSIMGSDPKVRPGAVDVVRHWQDLGYMILYITGRPDMQKQRVVSWLSQHNFPQGMIFFSDGLVHDPLRQKAIFLRNLMQECFIKITAAYGSTKDISVYSVLGLPASQIFIVGRPTKKYQTQCQFLSEGYAAHLAALEASHRSRPKKNNSRMILRKGSFGLHAQPEFLR--------KRN-HLRRTMSVQQPDPP---ATNPKPERAQSQPESDKDHERPLPALS----WARGAPKFESVP-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UHE1-1", "uniprot_id": "PITM3_MOUSE", "id": "Q3UHE1-1", "name": "Membrane-associated phosphatidylinositol transfer protein 3", "aln": "MAKAGSAGGPSPG---GGAPWHLRNVLSDSVESSDDEFFDAREEVAEGKNAILIGMSQWSSNDLVEQIETIGKLDERQGDGATACTSSILQEKQRELYRVSLRRQRFPAQGSIEIHEDGEEGCSQRSCKTHVLLLVLHGGNVLDTGSGDPSCKAADIHTFSSVLEKVMRAHFPAALGHILIKFVPCPAICSEAFSLVSNLNPYSHDEGCLGTSQDHVPLAALPLLAISSPQYQDAVATVIERANHIYGEFLKSSDGIGFNGQVCLIGDCVGGLLAFDAICYSAGPSGDSPGSSSRKGSISSTQDTP-VVVEEDCSLASSKRLSKSNVDVSSGVEDED-PKRPLPRKQSDSSTYDCEAITQHHAFLSSIHSSVLKDEAEAPAAGTPQLSEVSLGRFDFDVSDFFLFGSPLGLVLAMRRTVLPGIDGFQMRPACSQVYSFFHCADPSASRLEPLLEPKFHLVPPVSVPRYQRFPLGDGQSLLLADALHTHSPLFLEGSSRGSPPLLDAPASPPQAPRFQRTERRLSKGSSHSDSSESSDSLAPMGASRITAKWWGTKRIDYALYCPDVLTAFPTVALPHLFHASYWESTDVVAFILRQVMRYESASVKESTGLDPTALSPANPREKWLRKRTQVKLRNVTANHRANDVIAAEDGPQVLVGRFMYGPLDMVALTGEKVDILVMTEPSSGRWVHLDTEITNNSGRITYNVPRPRRLGVGVYPVKMVVRGDQTCAMSYLTVLPRGMECVVFSIDGSFAASVSIMGSDPKVRPGAVDVVRHWQDLGYMILYITGRPDMQKQRVVSWLSQHNFPQGMIFFSDGLVHDPLRQKAIFLRNLMQECFIKITAAYGSTKDISVYSVLGLPASQIFIVGRSTKKYQTQCQFLSEGYAAHLAALEASHRSRPKKNNSRMILRKGSFGLHAQPEFLR--------KRN-HLRRTMSVQQPDPP---AANPKPERAQSQPESDKDHERPLPALS----WARGPPKFESVP-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BZ71-1", "uniprot_id": "PITM3_HUMAN", "id": "Q9BZ71-1", "name": "Membrane-associated phosphatidylinositol transfer protein 3", "aln": "MAKAGRAGGPPPG---GGAPWHLRNVLSDSVESSDDEFFDAREEMAEGKNAILIGMSQWNSNDLVEQIETMGKLDEHQGEGTAPCTSSILQEKQRELYRVSLRRQRFPAQGSIEIHEDSEEGCPQRSCKTHVLLLVLHGGNILDTGAGDPSCKAADIHTFSSVLEKVTRAHFPAALGHILIKFVPCPAICSEAFSLVSHLNPYSHDEGCLSSSQDHVPLAALPLLAISSPQYQDAVATVIERANQVYREFLKSSDGIGFSGQVCLIGDCVGGLLAFDAICYSAGPSGDSPASSSRKGSISSTQDTP-VAVEEDCSLASSKRLSKSNIDISSGLEDEE-PKRPLPRKQSDSSTYDCEAITQHHAFLSSIHSSVLKDESETPAAGGPQLPEVSLGRFDFDVSDFFLFGSPLGLVLAMRRTVLPGLDGFQVRPACSQVYSFFHCADPSASRLEPLLEPKFHLVPPVSVPRYQRFPLGDGQSLLLADALHTHSPLFLEGSSRDSPPLLDAPASPPQASRFQRPGRRMSEGSSHSESSESSDSMAPVGASRITAKWWGSKRIDYALYCPDVLTAFPTVALPHLFHASYWESTDVVAFILRQVMRYESVNIKESARLDPAALSPANPREKWLRKRTQVKLRNVTANHRANDVIAAEDGPQVLVGRFMYGPLDMVALTGEKVDILVMAEPSSGRWVHLDTEITNSSGRITYNVPRPRRLGVGVYPVKMVVRGDQTCAMSYLTVLPRGMECVVFSIDGSFAASVSIMGSDPKVRPGAVDVVRHWQDLGYMILYITGRPDMQKQRVVSWLSQHNFPQGMIFFSDGLVHDPLRQKAIFLRNLMQECFIKISAAYGSTKDISVYSVLGLPASQIFIVGRPTKKYQTQCQFLSEGYAAHLAALEASHRSRPKKNNSRMILRKGSFGLHAQPEFLR--------KRN-HLRRTMSVQQPDPP---AANPKPERAQSQPESDKDHERPLPALS----WARGPPKFESVP-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P8F6-1", "uniprot_id": "A0A8M1P8F6_DANRE", "id": "A0A8M1P8F6-1", "name": "Membrane-associated phosphatidylinositol transfer protein 3", "aln": "MTDRMTQETRVPSRKHSASHWRLQNIAQESVESSDEEFFDAR-DVMEGKTALLLEMSQWNSNDLVEQIETLGHLEHS----------------RESLYR--LRHPRCAPQSSVDGLEDME-----RKCRTQLLILVIHGGHILDSGGGDPGGKAGDAATLASVLERVARAHFQAAADSMLVRLVPCPPVCADAFTLVSNLNPYSYDENCVSTSVDHLPLAALPILAIAAPHYQNAVAAVIAQANQVYRNFLQSPEGVGFTGQVCLVADCVGGVLCFDALCFSGDKQHRSPEGGSTNNSTESLKEKPGVVNSLSPTLRGSKRLSKSNIDVSTPCDVLSGIRHPLIRKQSDSCDADVASG-QREVFISSLSQ---DDQCGSRQALSP-------GCFEFEVSDCFLLGCPLGLVLAMRRTVVPGVDVAQLRPACSQIFNLFYPSDPSASRLEPLLHSVLTQLPPFPVPRYQRCPLGDGRSTLIVDTVLRHVTEGGVSADGAADQCYGGSVSR------RGSDRAVPLGSEGTAPSE------PVSISQVCSRWWGSKRLDYVLYCPDVLTTFPTIALPHLFHASYWESTDAVAFILRQVMRCDCLKAGEADCSDAIPISPSSPREKWLRRRTHVKLRNITANHRVHDVIVTEDGPQTLVGRFMYGPLDMVTLTGEKVDVFLKTQSGSGRWVLFDTVVTSSSGRVSYTIPDNKRLGVGVYPIKMVVKGDQTSAEAFLTVLPQGMECVVFSIDGSFAASVSLMGSDPKVRPGAVDVVRHWQDLGYLIIYITGRPDMQKQRVVSWLSQHNFPQGMVFFSEGLVHDPLRQKTIFLKSLVKECHIKISAAYGSMKDMSVYSTLGLAPNQIYIVGRPSKKHQHQCQFLSEGYAAHLSTLEFEHGSRSKKN--RMVLRQGSFGLSSKTDFLSPSPDFLSCKRTPLLRRAMSVQQPSPPSSSVSTPKPERAQSQPESHKDGPEIRIQYDDQDEEEEEEGRIQDVVL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:. *. ..: *:*:*: .:******:****** :: ***.*:*: ****.**********:*:*:. :..*** **: : ..*.*:: ** * *.*:*::*:**:***::**:*.***. **.* *::****:* **** ** . :*:::****.:*::**:***:*****:**.*:.:* **:******:***::*:**:***:** :**::* :**:*.:*:**.*****:.*****:*.***:*:*.. . ** ..* :.* .* ::.* *. . . .* .********:*:*: : . ::** ******. * : *:..*:**: . .*:. : * * * *:*:*** **:*.************:**:* *:******::.:*: :***********.. : :**..****** *****:* *:.*:: * . .:. : ....* : . * :. **. : .** *:. *:: ::***:**:**.********:***:***************.********** :. . *: *. .:**:.*******:**:*****:*****.:***.:*****.*************:*******::: ::..***** :** :*..***::*.:* :********:****:****.* ::*****:******************:***********************:*:**************************:***:**********:***:.*::**.***:***** **:****.***...**:****.:**:* *************::** .* **.*** **:**:***** ::.:** **. ***:******.** .:.************.** . . . :::.* ", "identical_positions": 546, "similar_positions": 257, "identity": "54.82%" }, { "cls_id": "homologset.agr.RGD:1308201", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A9E6-1", "uniprot_id": "A0A8I6A9E6_RAT", "id": "A0A8I6A9E6-1", "name": "", "aln": "---MLTWSSEEAMGSCCSCPEKDTVPDNHRNKFKVINVDDDGNE----LGSGVMELTDTELILYTRKRDSVKWHYLCLRRYGYDSNLFSFESGRRCQTGQGIFAFKCARAEELFNMLQEIMQNNSINVVEEPVVERNSHQTELEVPRTPRTPTTPGLGAQSLPNGYPRYPSFGDASSHPSSRHPSVGSARLPSVGEESTHPLLVAEEQVHTYVNTTGVQEERKNRASVHIPPEARVSNAESNTPKEEPSNTEDRDPHVLLKPEGVKFVLGPTPVQKQL-MEKEKLEQLGK----------DQVSGSGASSTEWDTGYDSDERRDVPPVNKLVYENINGLSIPSASGVRRGRLTSTSTSDTQNINNSAQRRPALLNYENLPSLPPVWEARKLSRDEDDNLGPKTPSLNGYHNNLDPMHNYVNTENVTVPASAHKIDCSRRRDCTPTVFNFDIRRPSLEH--RQLNYIQVDLEGGSDSDNPQTPKTPTTPLPQTPTRR-TELYAVIDIERTAAMSNLQKALPRDDGTSRKTRHNSTDLPM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C180-1", "uniprot_id": "FRS2_MOUSE", "id": "Q8C180-1", "name": "Fibroblast growth factor receptor substrate 2", "aln": "------------MGSCCSCPDKDTVPDNHRNKFKVINVDDDGNE----LGSGVMELTDTELILYTRKRDSVKWHYLCLRRYGYDSNLFSFESGRRCQTGQGIFAFKCARAEELFNMLQEIMQNNSINVVEEPVVERSSHQTELEVPRTPRTPTTPGLGAQNLPNGYPRYPSFGDASSHPSSRHPSVGSARLPSVGEESTHPLLVAEEQVHTYVNTTGVQEERKNRASVHVPPEARVSNAESNTPKEEPSNPEDRDPQVLLKPEGVRFVLGPTPVQKQL-MEKEKLEQLGK----------DPVSGSGAGNTEWDTGYDSDERRDVPPVNKLVYENINGLSIPSASGVRRGRLTSTSTSDTQNINNSAQRRPALLNYENLPSLPPVWEARKLSRDEDDNLGPKTPSLNGYHNNLDPMHNYVNTENVTVPASAHKIDYSKRRDCTPTVFNFDIRRPSLEH--RQLNYIQVDLEGGSDSDNPQTPKTPTTPLPQTPTRR-TELYAVIDIERTAAMSNLQKALPRDDGTSRKTRHNSTDLPM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WU20-1", "uniprot_id": "FRS2_HUMAN", "id": "Q8WU20-1", "name": "Fibroblast growth factor receptor substrate 2", "aln": "------------MGSCCSCPDKDTVPDNHRNKFKVINVDDDGNE----LGSGIMELTDTELILYTRKRDSVKWHYLCLRRYGYDSNLFSFESGRRCQTGQGIFAFKCARAEELFNMLQEIMQNNSINVVEEPVVERNNHQTELEVPRTPRTPTTPGFAAQNLPNGYPRYPSFGDASSHPSSRHPSVGSARLPSVGEESTHPLLVAEEQVHTYVNTTGVQEERKNRTSVHVPLEARVSNAESSTPKEEPSSIEDRDPQILLEPEGVKFVLGPTPVQKQL-MEKEKLEQLGR----------DQVSGSGANNTEWDTGYDSDERRDAPSVNKLVYENINGLSIPSASGVRRGRLTSTSTSDTQNINNSAQRRTALLNYENLPSLPPVWEARKLSRDEDDNLGPKTPSLNGYHNNLDPMHNYVNTENVTVPASAHKIEYSRRRDCTPTVFNFDIRRPSLEH--RQLNYIQVDLEGGSDSDNPQTPKTPTTPLPQTPTRR-TELYAVIDIERTAAMSNLQKALPRDDGTSRKTRHNSTDLPM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6Z5Y5-1", "uniprot_id": "A0A8M6Z5Y5_DANRE", "id": "A0A8M6Z5Y5-1", "name": "", "aln": "MAGWVQWCVKGAMGSCCSCPDKEIIPDNHHNKFKVINVDDDGNE----LGSGVMELTEEELILHTRKRDAVKWPYLCLRRYGYDSNLFSFESGRRCQTGQGIFAFKCARAEEIFNMLQDIMHNNSISVVEEPVLEP-------ELPATPHTPTTPGYSVPTVANGISRYPLF-DASSRPSSRHPSVGSTRLPSVGEESTHPLLLNDETVHTYVNTTGLQEERRCRSTGHTPLEPETSNHESAVP----ASPNEQEPCVVLEPESVKFVLGPTPVQRQR-QQQETGEEATNSEHTSYTPPVKTVNGNAGLMADCDTGYDSDERKETS------CEHHNGIST----GARRIRPP-VPLPDAHNANNSAQRRTALLNYENLPALPPVWEMRKPEEDE-----LKSPSLNGFHS-LDPQHNYVNTENVTVPLSAHKHNSQ------PSVFNFDLRRLGVGDPLRQLNYIEVEMDKVSDSSGPHTPKTPTTPLPATPTRR-TELYAVIDIERTAAMSSLQKAQPRDDGTSRKTRHNSTDLPM", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VLL4-1", "uniprot_id": "Q9VLL4_DROME", "id": "Q9VLL4-1", "name": "IRS-type PTB domain-containing protein", "aln": "------------MG-CITSSSKLNELRGHENVFRVRVAHLQPTPGTPIIRSGYLELTPRELIFQSPGCEPIVWALQHLRRYGLNNDLFSFEAGRRCMSGPGIYTFRVHNAEQLYPMFQRYINAVNTDAFVQGERER----------VNSAHSVSVNMGRTEGNNYLEPAPLMSRQLGNFHS-EPSSTSASYPLQANDS--QVDDSPPNLQSPVLIPSAYLDQPLRALQDCCLEGTASDLLSTPP----SGNRLTSRRRTMDLPPLESAPAPAPVLSPNDAVHMYAN-------------------VEALIFDLNN-----ER---------CYENVNRLELP--------LLPREPISNQEPATPTSLAGSCGVNYIVLDLDQPRSPVGPAGSSK---------AINGFGSGLSLISTPAAVTAPVTPEAGTTLDVP-----PPPMQTQSLNSISADTG-------DTQAKKVTECSGTQGYSTIDFIRTYALNKSSTELPETVTHRQHSSHDAEELRITRHSKCIRKAYSISE----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** * :...* .*.* *:* .. : . : ** :*** ***: : :.: * ***** :.:*****:**** :* **::*: .**::: *:* :: . ... : * .. ..: . . * * : .. * .** *: * .::* : ::: * .. :: *: . * .*: * * :. . . :. :. . .*:** : : . : :. ** *: * :. . . .: . . :: .. :** * * .: ::**: . *. . . . ..* :. . : *.: . .:. . :.: . ::....: .* . : .: *** .: .: :: . : .*.. **: * ", "identical_positions": 78, "similar_positions": 147, "identity": "14.5%" }, { "cls_id": "homologset.agr.RGD:1308202", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q80VW7-1", "uniprot_id": "AKNA_MOUSE", "id": "Q80VW7-1", "name": "Microtubule organization protein AKNA", "aln": "MASSGAKAQWVGPSLGQGPRRRRWAWAEEQ-DTDGRRDQGWGNSQSLPEAPSPELLEDFRRAQEHLPPLEWDPDMQ-------DSEESSGEETEADDASSPEGSTVPLPWLSRSNQQLDMSEEELDEASGRPEVDLAGESCTELECED------QGDSSPPPPGQGPAKGWVTFIKQGSNYRPSEHLEAQPSVEHSRTKSWSSGTVSLRQPSDSLGSTWEGDTEVPQPSILPKALPQSPCHNFPHPGDRNGGDVAPATPTEFRDSLAAPAQNAECSAGTWGEETTSLPSSRPEDQTWKRTKTSPKPLPSRFTGSVSPLSTRLGAIKKVVPQHKQGATLAGHSSSQAPKYGRGRRLNYPLPDFSKVGPRVRFPKDENYRPPKSRGHNRQ-QGSTRPLIFKSPAEIVRDVLLSSGEASLAKESSLAHTITRVPQEFQTPEQATELVHQLQEDYHKLLTKYAEAENTIDQLRLGAKVHLYSDPPQPSQSFCSGSMPQGSKVLSFSIPQPRVAEWWPDPAQDPQASEATGWPFPRTDLSPSSSPGVATPGRLPQSQGIATDQPSTGQTQALTSQASRLLAKVQSFEELVLAGHLPPQDQIKSLEQLRAAHMALEAEYLQACREELLDPQLDASQGSPRTLNLCRELEAEIYHLGQRLEELQDHMDQTQRETEPCRPD-LQDSTPTMSFLPQSAHLSMPSGPVSLPDGQT-YQEPATTTTTSPGSSCTLPINKKLSLS-IKTEESPRGLPVPLRDRTLQVEQDFHGLLERYLSVKSLPEALRDEDEDDLEEEEEEQDHQGPLEVDSPATAPGKTEAVRVPPGERPTQAEESHRDATQEDEEQMGPMKSPDFRPSMARDTYTPVLDTAEVAQRG---------TKAMVSHQSSLTSLEESRPSELLPRKALLRAGGPHTEEPWMVSPETDSGFVGSETSIVSPFTQTPEHRLSHVSTSGPSAQHLTASVPGDRTSHPKARGLMVPRRATETGIPRSRTQQHFSSLS-SPGRGAQSCHLEETSVAKIAVPRSEFKRQKQISKQLLPSGRTSPDSAPAPTAASTPHGSAESTANLLLNRTERDQAIKDLQAEVSRLRLQLEDSLHRPHPDGPACVASAFNHSTQTQEKLG-SSPSWGPHYGSKSTERLSREPNGVEPAEPMGRRRARSSSVPRDVPRLYLSSESESPAPRLSSEKSRTFEEHPEAAQWGTRPQSSSKRRERVSFRGQYTGQEYHILSPKAILKDSGTPSCPHCHPIRTQDTGSAVSRDTTRGSSAADTLRCALCGEVKSSAEADGSSSGPS--EKNTPKK--PSTPILKRKNRQTGSPVRMAPGLWYLAAAPPAPAPPALAYISSAPIMPYLPPTVYYAAPAPTSAQTASPQPARGP----RRTRHSVQLGLNDLEELQAALREAAQAAENVRSTTRQLSRSLSADLRHARSLRGSCLF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZLV5-1", "uniprot_id": "D3ZLV5_RAT", "id": "D3ZLV5-1", "name": "", "aln": "MASSGTKAQWAGSNLGQGPRRRRWAWAEEQ-DADGRGDQGWRNKQSLPEAITPELLEDFRQAQEHLPPLEWDPDMQ-------GSEESSAEDTEADDVSSPEGSPVPLPWLSRHSQRLGLSDEELDETPGSPEVDLAGESSTELECED------QGDLSPPVAGQEPARGWVASIKQGSNYRPSEHPEAQPSVEHSRTKSWSNATMGLGQPSDSLGSTWEGDTDVPQPDTLPEALPQSPCHNLLHPDDRNEGDVAPATPTEFRHSLAAPARNPERSAGTWGRETTSLPSSRPEDQSWKRTKASPKPLPSRFTGSVSPLSTRLGAVNKVVSQHKQGATVAGHSSSRVPKYGRGR-LNYPLPDFSKVGPRVRFPKDENYRPPKSRGHNRQ-QGSTRPLIFKSPAEIVRDVLLSSGDTPLAKESSLAHPVTRVPQEFQTPEQATELVHQLQEDYHKLLTKYAEAENTIDQLRLGAKVHLYSDPPQPSQSFCSGSMPQGSKVLSFSIPQPRSAEWWPDPAQDSQASEATGWPFPRTDLSPSSSPSMATPGRPHQSQGIAVDQPSTGQIQALTSQASRLLAKVESFEELVLAGHLPPQDQIKSLEQLRAAHMALEAEYVQACGEEHLDPQLDASQGSPRTLNLCRELEAEIYQLGQRLEELQDHIDQTRAEPEPCGTD-LQDSTPTIPFQPQPAHLPMPSGPVPPPDVQT-YQEPVTTTTS-PGNSCMLPMPKEVNLG-IRTEGSPRGLLVPLKDRKLQAEQDFHGLLERYLSVKSLPEALRVEDEEDPEEEEEQQDHPDTLKVDGSTAAPGKTEARRASPGQHPAQAEERHRAAIQEDKEQMVSMKSSNFQPSMARNRYTPVLDTAGVAQGG---------TKPMPSHQSSLTSLEESRPSDLLPRKALLRAGGPHTEEPWMVSPETDSGFVGSETSIVSPFTQTPEHQISHISTPGPSAQHLTVSAPGDGTSHPKVKGPVVPRRATEAGIPRSLTQRHHSSLS-SLRRGAQSCHLEETPVAKIAVPRSEFKRQKQISKQHLPSGTTSPDSAPAPTAASMPHGSAESTANLLLTRTERDQAIKDLQAEVSRLRLQLEDSLHRPRPDSPACVAPAFNCSTQTQKKLVDSSPSWGSRYGSKSTERLFGEPSGAEPAEPMGRRQVRSSSVPRDVPRLS-SSESESPAPRLSSEKNRTFEEHPQAAQWGTRPLGSTKRRERVSFWGQYTGQEYHILSPKTNLKDSGTASCPHCQPIRTQDTGNAVSREP-LGSSAADTLRCSLCGGVKPSAEADGPSPAPS--EKNTPQKPAPSTPSLKRKKRQTDSPVRMLPGLWYLAAAPPAPAPPALAYIS-APIMPYPPPTVYYATPAPTSVHTASPQPAQGP----RRTRHSVQLGLNDLEELQAALREAARAAENVRSTTRQLSHSLSADLRHARSLRGSCLF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7Z591-1", "uniprot_id": "AKNA_HUMAN", "id": "Q7Z591-1", "name": "Microtubule organization protein AKNA", "aln": "MASSETEIRWAEPGLGKGPQRRRWAWAEDKRDVDRSSSQSWEEERLFPNATSPELLEDFRLAQQHLPPLEWDPHPQPDGHQDSESGETSGEEAEAEDVDSPASSHEPLAWLPQQGRQLDMTEEEPDGTLGSLEVEEAGESSSRLGYEAGLSLEGHGNTSPMALGHGQARGWVASGEQASGDKLSEHSEVNPSVELSPARSWSSGTVSLDHPSDSLDSTWEGETDGPQPTALAETLPEGPSHHLLSPDGRTGGSVARATPMEFQDSSAPPAQSPQHATDRWRRETTRFFCPQPKEHIWKQTKTSPKPLPSRFIGSISPLNPQPRPTRQGRPLPRQGATLAGRSSSNAPKYGRGQ-LNYPLPDFSKVGPRVRFPKDESYRPPKSRSHNRKPQAPARPLIFKSPAEIVQEVLLSSGEAALAKDTPPAHPITRVPQEFQTPEQATELVHQLQEDYHRLLTKYAEAENTIDQLRLGAKVNLFSDPPQPNHSIHTGMVPQGTKVLSFTIPQPRSAEWWPGPAEDPQASAASGWPSARGDLSPSSLTSMPTLGWLPENRDISEDQSSAEQTQALASQASQFLAKVESFERLIQAGRLMPQDQVKGFQRLKAAHAALEEEYLKACREQHPAQPLAGSKGTPGRFDPRRELEAEIYRLGSCLEELKEHIDQTQQEPEPPGSDSALDSTPALPCLHQPTHLPAPSGQAPMPAIKTSCPEPATTTAAASTGPCPLHVNVEVSSGNSEVEDRPQDPLARLRHKELQMEQVYHGLMERYLSVKSLPEAMRMEEEEEGEEEEEEEGGGDSLEVDGVAATPGKAEATRVLPRQCPVQAEKSHGAPLEEATEKMVSMKPPGFQASLARDGHMSGLGKAEAAPPGPGVPPHPPGTKSAASHQSSMTSLEGSGISERLPQKPLHRGGGPHLEETWMASPETDSGFVGSETSRVSPLTQTPEHRLSHISTAGTLAQPFAASVPRDGASYPKARGSLIPRRATEPSTPRSQAQRYLSSPSGPLRQRAPNFSLERTLAAEMAVPGSEFEGHKRISEQPLPNKTISPPPAPAPAAAPLPCGPTETIPSFLLTRAGRDQAICELQEEVSRLRLRLEDSLHQPLQGSPTRPASAFDRPARTRGRPADSPATWGSHYGSKSTERLPGEPRGEEQIVPPGRQRARSSSVPREVLRLSLSSESELPSLPLFSEKSKTTKDSPQAARDGKRGVGSAGWPDRVTFRGQYTGHEYHVLSPKAVPKGNGTVSCPHCRPIRTQDAGGAVTGDP-LGPPPADTLQCPLCGQVGSPPEADGPGSATSGAEKATTRRKASSTPSPKQRSKQAGSSPRPPPGLWYLATAPPAPAPPAFAYISSVPIMPYPPAAVYYAPAGPTSAQPAAKWPPTASPPPARRHRHSIQLDLGDLEELNKALSRAVQAAESVRSTTRQMRSSLSADLRQAHSLRGSCLF", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**** :: :*. ..**:**:********:: *.* .*.* :.: :*:* :******** **:*********. * * *:*.*::**:*..** .* **.**.: .::*.:::** * : * **: ****.:.* * :*: ** *: *:***: :*.*. : *** *.:**** * ::***..*:.* :*****.*****:*: *** *.::**:.*.*:: *..*. *.** *** **:.* *.**:..: ::. * .*** : ..:*::: **:**:********* **:***..: . .: . :****:**:***..******: *********************.*******.***: *..:************::******::.***::. **.:*************************:*********************:*:******.:*: :* :***:*****:***** *****.**:*.*** *:*** .* ****** ..:.* * :.:.*: **.*: * ***:****::****:***.*: **:* ****:*.:::*:*** *** **::** *: * .*:*:* :: ********:**. ****::*:***: *.** .* ****::. *.:**. *** .. * :* **.***:: . ..* * : ::. . ..* *:. . *:.: ** ** :***:************:* *:*:: *****::. ..*:**. :::***:** *. * : *.***: * . :* *:* .**...*:.*:**: : . *..* .* * **. *****:**** * *: **:*.* *.**** **.**.************** ***:******::**:**.*. ** ::.*.* * :*:**.:* ::******.. *** :*:: ** * . : * . **.* .*::*** ***: :*:**:* **. ** .****:**. * *.:*: ..:**.*: ***** :** *******:******:* ..*: *.**: .::*: : *..:**.:********* ** * * * **::.*******:* ** ***** *: * ***.:* :: *:**: *.* .*: :**:* *****:***:****: *..** *****:******:*.**: :. *...****:*.*** * ...****.....* ** *.:: .*** *::.:*:.*. * *******:*********:**** .***** *.:****...***.:.*: *. .. ** ***:**.*.*****: ** .*.:***.*******: *******:*:********", "identical_positions": 768, "similar_positions": 394, "identity": "53.3%" }, { "cls_id": "homologset.agr.RGD:1308203", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "M0RDI4-1", "uniprot_id": "M0RDI4_RAT", "id": "M0RDI4-1", "name": "Zinc finger protein 250", "aln": "MAAAGLLPLPAAP-----QAKVTFEDVAVLLSQEEWARLGPAQRGLYRNVMMETYGNVVSLGLPGSKPVVISQLERGEDPWVLDGQETELSQGLGSDHS---------------------ECKAKEENQNTDSNAQPLISDEASAMLAETPLRKVDEH-YKTEPNFCPSPKSVGPQNAHVLNPSVPVARPQMAPSGERPYICIECGKCFGRSSHLLQHQRIHTGEKPYVCHVCGKAFSQSSVLSKHRRIHTGEKPYECNECGKAFRVSSDLAQHHKIHTGEKPHECLECGKAFTQLSHLIQHQRIHTGERPYVCPLCGKAFNHSTVLRSHQRVHTGEKPHGCSECGKTFSVKRTLLQHQRVHTGEKPYTCSECGKAFSDRSVLIQHHNVHTGEKPYECSECGKTFSHRSTLMNHERIHTQEKPYACYECGKAFVQHSHLIQHQRVHTGEKPYVCGECGHAFSARRSLIQHERIHTGEKPFQCTECGKAFSLKATLIVHLRTHTGEKPYECNSCGKAFSQYSVLIQHQRIHTGEKPYECGECGRAFNQHGHLIQHQKVHKKL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TNU6-1", "uniprot_id": "ZN250_MOUSE", "id": "Q7TNU6-1", "name": "Zinc finger protein 250", "aln": "MAAAGLLPLPAAP-----QAKVTFEDVAVLLSQEEWARLGPAQRGLYRHVMMETYGNVVSLGLPGSKPVVISQLERGEDPWVLDGQGTELSQSLGSDHS---------------------ECKAKEENQNTDLNVPPLISDEASATLTETPLRKVAEERYKTEPKVCPSPKPIGPQNAHGLNPSVPVARPQTAPSVERPYICIECGKCFGRSSHLLQHQRIHTGEKPYVCHVCGKAFSQSSVLSKHRRIHTGEKPYECNECGKAFRVSSDLAQHHKIHTGEKPHECLECGKAFTQLSHLIQHQRIHTGERPYVCPLCGKAFNHSTVLRSHQRVHTGEKPHGCSECGKTFSVKRTLLQHQRVHTGEKPYTCSECGKAFSDRSVLIQHHNVHTGEKPYECSECGKTFSHRSTLMNHERIHTQEKPYACYECGKAFVQHSHLIQHQRVHTGEKPYVCGECGHAFSARRSLIQHERIHTGEKPFQCTECGKAFSLKATLIVHLRTHTGEKPYECNSCGKAFSQYSVLIQHQRIHTGEKPYECGECGRAFNQHGHLIQHQKVHKKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P15622-1", "uniprot_id": "ZN250_HUMAN", "id": "P15622-1", "name": "Zinc finger protein 250", "aln": "MAAARLLPVPAGPQPLSFQAKLTFEDVAVLLSQDEWDRLCPAQRGLYRNVMMETYGNVVSLGLPGSKPDIISQLERGEDPWVLDRKGAKKSQGLWSDYSDNLKYDHTTACTQQDSLSCPWECETKGESQNTDLSPKPLIS-EQTVILGKTPLGRIDQENNETKQSFCLSPNSVDHREVQVLSQSMPLTPHQAVPSGERPYMCVECGKCFGRSSHLLQHQRIHTGEKPYVCSVCGKAFSQSSVLSKHRRIHTGEKPYECNECGKAFRVSSDLAQHHKIHTGEKPHECLECRKAFTQLSHLIQHQRIHTGERPYVCPLCGKAFNHSTVLRSHQRVHTGEKPHRCNECGKTFSVKRTLLQHQRIHTGEKPYTCSECGKAFSDRSVLIQHHNVHTGEKPYECSECGKTFSHRSTLMNHERIHTEEKPYACYECGKAFVQHSHLIQHQRVHTGEKPYVCGECGHAFSARRSLIQHERIHTGEKPFQCTECGKAFSLKATLIVHLRTHTGEKPYECNSCGKAFSQYSVLIQHQRIHTGEKPYECGECGRAFNQHGHLIQHQKVHRKL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**** ***:**.* ***:***********:** ** ********:******************* :************** : :: **.* **:* **::* *.**** . **** * :. * :*** :: :. :*: ..* **:.:. ::.: *. *:*:: * .** ****:*:*************************** ********************************************************** ************************************************** *.*****************:**********************************************************:******************************************************************************************************************************************:**", "identical_positions": 458, "similar_positions": 45, "identity": "81.64%" }, { "cls_id": "homologset.agr.RGD:1308204", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9HBU6-1", "uniprot_id": "EKI1_HUMAN", "id": "Q9HBU6-1", "name": "Ethanolamine kinase 1", "aln": "----------MLCGRPRSSSDNRNFLRERAGLSSAAVQTRIGNSAASRRSPAARPPVPAPPALPRGRPGTEGSTSLSAPAVLVVAVAVVVVVVSAVAWAMANYIHVPPG--SPEVPKLNVTVQDQEEHRCREGALSLLQHLRPHWDPQEVTLQLFTDGITNKLIGCYVGNT----------------------------------------------------MEDVVLVRIYGNKTELLVDRDEEVKSFRVLQAHGCAPQLYCTFNNGLCYEFIQG-EALDPKHVCNPAIFRLIARQLAKIHAIHAHNG----WIPKSNLWLKMGKYFSLIPTGFADEDINKRFLSDIPSS--QILQEEMTWMKEILSN----------------------------------------------LGSPVVLCHNDLLCKNIIYNE------KQGDVQFIDYEYSGYNYLAYDIGNHFNEFAGVS-------DVDYSLYPDRELQSQWLRAYLEAYKEFKGFGTEVTEKEVEILFIQVNQFALASHFFWGLWALIQAKYSTIE------------------------------------------------FDFLGYAIVRFNQYFKMKPEVTALKVPE----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LLY9-1", "uniprot_id": "A0ABK0LLY9_RAT", "id": "A0ABK0LLY9-1", "name": "ethanolamine kinase", "aln": "---------------------------------------------------------------------------------------------------MANYIHVPPG--SPEVPKLDVTVQDQEEQRCRDGALSLLQHLRPHWDPREVTLQLFTDGITNKLIACYVGDT----------------------------------------------------MDDVVLVRIYGNKTELLVDRDEEVKSFRVLQAHGCAPQLYCTFNNGLCYEFIQG-EALDPQHVCNPAIFRLIARQLAKIHAIHAHNG----WIPKSNLWLKMGKYFSLIPTGFADEDINKRFLSEIPSP--QLLQEEMTWMKEILSS----------------------------------------------LGSPVVLCHNDLLCKNIIYNE------KQGDVQFIDYEYSGYNYLAYDIGNHFNEFAGVS-------DVDYSLYPDRELQGQWLRSYLEAYKEYKGFGSDVTEKEVETLFIQVNQFALASHFFWGLWALIQAKYSTIE------------------------------------------------FDFLGYAIVRFNQYFKMKPEVTALKMPE----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D4V0-1", "uniprot_id": "EKI1_MOUSE", "id": "Q9D4V0-1", "name": "Ethanolamine kinase 1", "aln": "---------------------------------------------------------------------------------------------------MANYIHVPPG--SPEVPKLDVTVQDQEEQRCRDGALSLLRHLRPHWDPREVTLQLFTDGITNKLIACYVGDT----------------------------------------------------MEDVVLVRIYGNKTELLVDRDEEVKSFRVLQAHGCAPQLYCTFNNGLCYEFIQG-EALDPQHVCNPAIFRLIARQLAKIHAIHAHNG----WIPKSNLWLKMGKYFSLIPTGFADENINKRFLSEIPSP--QLLQEEMTWMKELLSS----------------------------------------------LGSPVVLCHNDLLCKNIIYNE------KQGDVQFIDYEYSGYNYLAYDIGNHFNEFAGVS-------DVDYSLYPDRELQGQWLRSYLEAYKEYKGFGSDVTEKEVETLFIQVNQFALASHFFWGLWALIQAKYSTIE------------------------------------------------FDFLGYAVVRFNQYFKMKPEVTALKMPE----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P54352-2", "uniprot_id": "EAS_DROME", "id": "P54352-2", "name": "Ethanolamine kinase", "aln": "-----------------MGTETKSNSYTGQISTSGGNPKVMKDSLSLVRQTVNQQTLSLSQSNQVQNQLNSHSNSNSYPNPSGSEN-------KNENEQNSRDIRAKPEDKSRKEAIVPFVPIFVEEADVIQGAKELLKVIRPTWDLSHVEFKSFTDGITNKLVGCFHKEISKLNDENGGSYLPIKTQGLSPVQSEDPVIIEKEDDDEFTDDRAADDGSPVQYSDNVVLVRIYGNKTDLLIDRKAETQNFLLLHTYGLAPSLYATFKNGLVYEYVPG-TTLNTDSVLCPEIWPLVARRMAEMHRKVRKHGDSSATKPMPMIWKKTQSFLDLVPERFSDAEKHKRVKETFLPI--GRLREEFNKLYEYLEA----------------------------------------------LDSPIVFSHNDLLLGNVIYTQ------SLNTVNFIDYEYADYNFQAFDIGNHFAEMCGVD-------EVDYSRYPKREFQLQWLRVYLEEYLQ----RSNIQNDEVELLYVQVNQFALASHIFWTVWSLLQAEHSTID------------------------------------------------FDYVGYAFLRYNEYLARKVEFLSLTAAKNNK-------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P20485-1", "uniprot_id": "KICH_YEAST", "id": "P20485-1", "name": "Choline kinase", "aln": "----MVQESRPGSVRSYSVGYQARSRSSSQRRHSLTRQRSSQRLIRTISIESDVSNITDDDDLRAVNEGVAGVQLDVSETANKGPRRASATDVTDSLGSTSSEYIEIPFVKETLDASLPSDYLKQDILNLIQSLKISKWYN--NKKIQPVAQDMNLVKISGAMTNAIFKVEYP--------------------------------------------------KLPSLLLRIYGPNIDNIIDREYELQILARLSLKNIGPSLYGCFVNGRFEQFLENSKTLTKDDIRNWKNSQRIARRMKELHVGVPLLS--SERKNGSACWQKINQWLRTIEKVDQWVGDPKNIENSLLCENWSKFMDIVDRYHKWLISQEQGIEQVNKNLIFCHNDAQYGNLLFTAPVMNTPSLYTAPSSTSLTSQSSSLFPSSSNVIVDDIINPPKQEQSQDSKLVVIDFEYAGANPAAYDLANHLSEWMYDYNNAKAPHQCHADRYPDKEQVLNFLYSYVSHLRGG---AKEPIDEEVQRLYKSIIQWRPTVQLFWSLWAILQSGKLEKK--EASTAITREEIGPNGKKYIIKTEPESPEEDFVENDDEPEAGVSIDTFDYMAYGRDKIAVFWGDLIGLGIITEEECKNFSSFKFLDTSYL-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q03764-1", "uniprot_id": "EKI1_YEAST", "id": "Q03764-1", "name": "Ethanolamine kinase", "aln": "MYTNYSLTSSDAMPRTYLVG-TASPEMSKKKRQSANCDKPTRRVIHIIDTN-EHSEVDLKNELPITCTNEDGEMTSSSWTS-----------------QTANDFLKLAYVNAKLDPSLPSQYFKQDIINVLQSLEIPGWSVPGSKESSLNKNLLTLTQIKGALTNVIYKIHYP--------------------------------------------------NLPPLLMRIFGDSIDSVIDREYELKVIARLSFYDLGPKLEGFFENGRFEKYIEGSRTSTQADFIDRDTSIKIAKKLKELHCTVPLTH--KEITDQPSCWTTFDQWIKLIDSHKEWVSNNVNISENLRCSSWNFFLKSFKNYKRWLYN---------------------------DSAFTSKLLREDDKDSMINSGLKMVFCHNDLQHGNLLFKSKGKDDISVGDLTIIDFEYAGPNPVVFDLSNHLNEWMQDYNDVQS-FKSHIDKYPKEEDILVFAQSYINHMNEN---HVKIASQEVRILYNLIIEWRPCTQLFWCLWALLQSGRLPQRPLIEGEKLMSEKAGLGDETHLMEHKNKENGKYDCSEDD---------SFNYLGFCKEKMSVFWGDLITLGVI-DKDCPDIGKTDYLDTKLIF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . : : :. . *.. : :*:**:* . : ::**. * : : * . .*.* * ** ::: . : . :*::: ::* . * . .:: : .. . : : . . . * :: .. : : . . . : .**:**:. * .:*:.**: * . . . **..* : *:. . ..**. *: : :: ::** :*:::*: *:::.: : : . : . ", "identical_positions": 39, "similar_positions": 102, "identity": "6.04%" }, { "cls_id": "homologset.agr.RGD:1308205", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4A2F2-1", "uniprot_id": "D4A2F2_RAT", "id": "D4A2F2-1", "name": "", "aln": "MNRGHRHGVSSGCLG---TMEVKSKFGAEFRRFSLERSKPGK-FEEFYGLLQHVHKIPNVDVLVGYADIHG-DLLPINNDDNYHKAVSTANPLLRVFIQKKEEA-DYSAFGTDTLIRKKNVLSNVLRPDNHRKKPHIVISMPQDFRPVSSIIDVDILPETHRRVRLYKYGTEKPLGFYIRDGSSVRVTPHGLEKVPGIFISRLVPGGLAQSTGLLAVNDEVLEVNGIEVSGKSLDQVTDMMIANSRNLIITVRPANQRNNVVRNSRTSGSSGQSTDNSLLGYPQQAGASLEPEDQDSDEDDIIIEGSGEPQQIPKATPEALSLESLTQIELSFESGQNGFSPLQDTSLVAVPSSLDTESESRAPDQKLLEEDGTIITL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JK83-1", "uniprot_id": "PAR6B_MOUSE", "id": "Q9JK83-1", "name": "Partitioning defective 6 homolog beta", "aln": "MNRGHRHGASSGCLG---TMEVKSKFGAEFRRFSLERSKPGK-FEEFYGLLQHVHKIPNVDVLVGYADIHG-DLLPINNDDNYHKAVSTANPLLRIFIQKKEEA-DYSAFGTDTLIRKKNMLSNVLRPDNHRKKPHIVISMPQDFRPVSSIIDVDILPETHRRVRLYKYGTEKPLGFYIRDGSSVRVTPHGLEKVPGIFISRLVPGGLAQSTGLLAVNDEVLEVNGIEVSGKSLDQVTDMMIANSRNLIITVRPANQRNNVVRNSRTSGSSSQSTDNSLLGFPQQVEASFEPEDQDSDEDDIIIEDSGEPQQIPKATP-AQSLESLTQIELSFESGQNGFSPPQDTSLVPVPGSLDTELESRAPDQKLLEEDGTIITL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BYG5-1", "uniprot_id": "PAR6B_HUMAN", "id": "Q9BYG5-1", "name": "Partitioning defective 6 homolog beta", "aln": "MNRSHRHGAGSGCLG---TMEVKSKFGAEFRRFSLERSKPGK-FEEFYGLLQHVHKIPNVDVLVGYADIHG-DLLPINNDDNYHKAVSTANPLLRIFIQKKEEA-DYSAFGTDTLIKKKNVLTNVLRPDNHRKKPHIVISMPQDFRPVSSIIDVDILPETHRRVRLYKYGTEKPLGFYIRDGSSVRVTPHGLEKVPGIFISRLVPGGLAQSTGLLAVNDEVLEVNGIEVSGKSLDQVTDMMIANSRNLIITVRPANQRNNVVRNSRTSGSSGQSTDNSLLGYPQQIEPSFEPEDEDSEEDDIIIEDNGVPQQIPKAVPNTESLESLTQIELSFESGQNGFIPSNEVSLAAIASSSNTEFETHAPDQKLLEEDGTIITL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O97111-1", "uniprot_id": "O97111_DROME", "id": "O97111-1", "name": "", "aln": "MSKNKINTTSATAASDTNLIEVKSKFDAEFRRWSFKRNEAEQSFDKFASLIEQLHKLTNIQFLILYIDPRDNDLLPINNDDNFGRALKTARPLLRVIVQRKDDLNEYSGFGT---MKPRNLIGSILMGHTPVKTKAPSISIPHDFRQVSAIIDVDIVPETHRRVRLLKHGSDKPLGFYIRDGTSVRVTASGLEKQPGIFISRLVPGGLAESTGLLAVNDEVIEVNGIEVAGKTLDQVTDMMVANSSNLIITVKPANQR---TLTSTHRGS--FSRNSQLSSGSHHTNNTNTSDEIEHDDQDDIVDLTG---------------VTLDESPTSTSAGNHNHQPP----LSSSPSSHHQQAASNASTIMASDVKDGVLHL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.:.: : ..: . . :******.*****:*::*.:. : *::* .*::::**:.*::.*: * * :. **********: :*:.**.****:::*:*:: :**.*** :: :*:: .:* .. *. **:*:*** **:******:********* *:*::**********:*****. **** **************:***********:*******:**:********:*** ******:***** . .* ** * :..* . .:: : .:: : :::* *:: .* :* : * .:*::.. * * . ..* . : :.*. : .. :: *", "identical_positions": 166, "similar_positions": 113, "identity": "43.92%" }, { "cls_id": "homologset.agr.RGD:1308207", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "O54946-1", "uniprot_id": "DNJB6_MOUSE", "id": "O54946-1", "name": "DnaJ homolog subfamily B member 6", "aln": "-MVDYYEVLGVQRHASPEDIKKAYRKQALKWHPDKNPENKEEAERKFKQVAEAYEVLSDAKKRDIYDKYGKEGLNGGGGGGGIHFDSPFEFGFTFRNPDDVFREFFGGRDPFSFDFFEDPFDDFFGNRRGPRGNRSRGAGSFFSTFSGFPSFGSGFPAFDT----GFTPFGSLGHGGLTSFSSTSFGGSG-MGNFKSISTSTKIVN----GKKITTKRIVENGQERVEVEEDGQLKSLTINGVADENALAEECQRRGQPTPALAPGPAPAPVRVPSQARPLAPTPAPTPAPTPAPAPAQTPAPSVSTRPQKPPRPAPTAKLGSKSNWEDD-EQDRQRVPGNWDAPMTSAGLKEGGKRKKQKQKEDLKKKKSTKGNH-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AYU3-1", "uniprot_id": "DNJB6_RAT", "id": "Q6AYU3-1", "name": "DnaJ homolog subfamily B member 6", "aln": "-MVDYYEVLGVQRHASPEDIKKAYRKQALKWHPDKNPENKEEAERKFKQVAEAYEVLSDAKKRDIYDKYGKEGLNGGGGGGGSHFDSPFEFGFTFRNPDDVFREFFGGRDPFSFDFFEDPFDDFFGNRRGPRGSRSRGAGSFFSAFSGFPSFGSGFPAFDT----GFTPFGSLGHGGLTSFSSASFGGSG-MGNFKSISTSTKIVN----GKKITTKRIVENGQERVEVEEDGQLKSLTINGVADENALAEECRRRGQPTPALAPGPAPAPARVPSQARP--PTPAPTPAP------AQTPAPSVSTRPQKPPRPAPTAKLVSKSNWEDE-EQDRQRVPGNCDAPMTSAGLKEGGKRKKQKQKEDSKKKKSTKGNH-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75190-1", "uniprot_id": "DNJB6_HUMAN", "id": "O75190-1", "name": "DnaJ homolog subfamily B member 6", "aln": "-MVDYYEVLGVQRHASPEDIKKAYRKLALKWHPDKNPENKEEAERKFKQVAEAYEVLSDAKKRDIYDKYGKEGLNGGGGGG-SHFDSPFEFGFTFRNPDDVFREFFGGRDPFSFDFFEDPFEDFFGNRRGPRGSRSRGTGSFFSAFSGFPSFGSGFSSFDT----GFTSFGSLGHGGLTSFSSTSFGGSG-MGNFKSISTSTKMVN----GRKITTKRIVENGQERVEVEEDGQLKSLTINGVADDDALAEERMRRGQ---------------------------------------NALPAQPAGLRPPKPPRPASLLRHAPHCLSEEEGEQDRPRAPGPWDPLASAAGLKEGGKRKKQKQREESKKKKSTKGNH-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AA54FRM3-1", "uniprot_id": "A0AA54FRM3_DANRE", "id": "A0AA54FRM3-1", "name": "", "aln": "MEEDYYHILGVTKSASPDDIKKAYRKLALKWHPDKNPNDKEEAEKRFKEISEAYEVLSDENKRRDYDRYGKQGLSNRGG----HYDDEYMGGFTFRNPEDVFREFFGGHDPFADFFADDPFEGFFGGRRHRGMSRSRTAGPFFPGFS---PFGPSFSGFDT----GFSPFGPMGGGSFSSFSSSPFGGGGGMRNFTSISTSTKFIN----GKRITTKRIVENGQERVEVEEDGQLKSLTVNAISDD---SEERRRQNT---------------------------------------LCGPAPHNRYLRNVAQNPSEKEEVEE----EDRGLQNLGIAKGFFDTRRKKLSLKESDTKKKRTPRLTPRIGVWF-----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A8DYF7-1", "uniprot_id": "A8DYF7_DROME", "id": "A8DYF7-1", "name": "", "aln": "-MVDYYKILDVSRSATDSEVKKAYRKLALKWHPDKNPDNLDEANKRFRELSEAYEVLSDARKRRIYDARATLHKSSNSGSS----SSNSSSYTRYRNGGTGGSSSYG--RDYDYDYYPGSGYGSGSGRRSGNRYQAFTFRNIFEGTPFHKMFEKKRRIYDEYGKDGLGDRGQSRSHARHHYSTHDFDDFDILGGFQFAFRPPEEVFREFFGIHSPFADLFRDANGHSNGSTSGSSGSRRNGGSSGSSRHHHHHHQHKVASP------------------------------------FGAPMLNYSMMDFFMPTSGFTSFSSMTHGNGSSGVTHISSGPGASVKRTSTSTVFVNGKKLMTKRVVENGKETVFSYENDVLKSKTVMGSLQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***.:*.* : *: .::****** **********:: :**:::*::::******** .** ** .. .. .* .. :** . :* : : .. . ..** :: :* . * :* *: * . :*: *.. . : .* ..: : * : . :..:.: : : . .*. * .. :.. .. :: * .. . . * . : ...: . ", "identical_positions": 56, "similar_positions": 87, "identity": "14.4%" }, { "cls_id": "homologset.agr.RGD:1308208", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8NC69-1", "uniprot_id": "KCTD6_HUMAN", "id": "Q8NC69-1", "name": "BTB/POZ domain-containing protein KCTD6", "aln": "MDNGDWGYMMTDPVTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDPQGNYFIDRDGPLFRYVLNFLRTSELTLPLDFKEFDLLRKEADFYQIEPLIQCLNDPKPLYPMDTFEEVVELSSTRKLSKYSNPVAVIITQLTITTKVHSLLEGISNYFTKWNKHMMDTRDCQVSFTFGPCDYHQEVSLRVHLMEYITKQGFTIRNTRVHHMSERANENTVEHNWTFCRLARKTDD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BNL5-1", "uniprot_id": "KCTD6_MOUSE", "id": "Q8BNL5-1", "name": "BTB/POZ domain-containing protein KCTD6", "aln": "MDNGDWGYMMSDPVTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDPQGNYFIDRDGPLFRYVLNFLRTSELTLPLDFKEFDLLRKEADFYQIEPLIQCLNDPRPLYPMDTFEEVVELSSTRKLSKYSNPVAVIITQLTITTKVHSLLEGISNYFTKWNKHMMDTRDCQVSFTFGPCDYHQEVSLRVHLMEYITKQGFTIRNTRVHHMSERANENTVEHNWTFCRLARKTDD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3V6Z2-1", "uniprot_id": "G3V6Z2_RAT", "id": "G3V6Z2-1", "name": "", "aln": "MDNGDWSYMMTDPVTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDPQGNYFIDRDGPLFRYVLNFLRTSELTLPLDFKEFDLLRKEADFYQIEPLIQCLNDPKPLYPMDTFEEVVELSSTRKLSKYSNPVAVIITQLTITTKVHSLLEGISNYFTKWNKHMMDTRDCQVSFTFGPCDYHQEVSLRVHLMEYITKQGFTIRNTRVHHMSERANENTVEHNWTFCRLARKTDD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6DG99-1", "uniprot_id": "KCTD6_DANRE", "id": "Q6DG99-1", "name": "BTB/POZ domain-containing protein KCTD6", "aln": "MDNGDWGHRLTHPVTLNVGGHLYTTSISTLQRYPDSMLGAMFRGDFPTTRDAQGNYFIDRDGTLFRYILNFLRTSELTLPVDFTELDLLRKEADFYQIEPLIQCLNDPKPLYPLDTFEQVVELSSTRKLSKYSNPVAVIITQLTITTKVHSLLEGISNNFTKWNKHMMDTRDCQVSFTFGPCDYHQEVSLRVHLMDYITKQGFTIRNTRVHHMSERANENTVEHHWTFCRLAYKVED", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2BL96-1", "uniprot_id": "A0A8M2BL96_DANRE", "id": "A0A8M2BL96-1", "name": "", "aln": "MENGDWTHMMMDTVTLNVGGHLYTTSLSTLQRYPDSMLGAMFRGDFPTTRDTQGNYFIDRDGPLFRYILNFLRTSKLTLPCDFKETELLRKEADFYQIEPLIQCLGETKPLYPLDTFEQVVELSSTRKLSKYSNPVAVIITQLTITTKVHALLEGISNNFTRWNKHMMDTRDFQVSFTFGPCDYHQEVSLRVHLVEYISKQGFTIRNTRVHHMSERANENTVEHHWTFCRVAQKVED", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:**** : : ..*************::** *********** *****:**.**********.****:*******:**** **.* :******************.:.:****:****:*******************************:******* **:********** *********************::**:*************************:*****:* *.:*", "identical_positions": 198, "similar_positions": 29, "identity": "83.54%" }, { "cls_id": "homologset.agr.RGD:1308210", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "B5DFK7-1", "uniprot_id": "AB17C_RAT", "id": "B5DFK7-1", "name": "Alpha/beta hydrolase domain-containing protein 17C", "aln": "MPEPGPRMNGFSLGELCWLFCCPPCPSRIAAKLAFLPPEPTYTVLAPEQR-----APAPAATPAPAPAAQPAP--AEEGAG--PGACSLHLSERADWQYSQRELDAVEVFFSRTARDNRLGCMFVRCAPSSRYTLLFSHGNAVDLGQMCSFYIGLGSRINCNIFSYDYSGYGVSSGKPSEKNLYADIDAAWQALRTRYGVSPENIILYGQSIGTVPTVDLASRYECAAVILHSPLMSGLRVAFPDTRKTYCFDAFPSIDKISKVTSPVLVIHGTEDEVIDFSHGLAMYERCPRAVEPLWVEGAGHNDIELYAQYLERLKQFISHELPNS--------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VCV1-1", "uniprot_id": "AB17C_MOUSE", "id": "Q8VCV1-1", "name": "Alpha/beta hydrolase domain-containing protein 17C", "aln": "MPEPGPRMNGFSLGELCWLFCCPPCPSRIAAKLAFLPPEPTYTVLAPEQR-----APAPAATPAPAPAAQPAP--AEEGAG--PGACSLHLSERADWQYSQRELDAVEVFFSRTARDNRLGCMFVRCAPSSRYTLLFSHGNAVDLGQMCSFYIGLGSRINCNIFSYDYSGYGVSSGKPSEKNLYADIDAAWQALRTRYGVSPENIILYGQSIGTVPTVDLASRYECAAVILHSPLMSGLRVAFPDTRKTYCFDAFPSIDKISKVTSPVLVIHGTEDEVIDFSHGLAMYERCPRAVEPLWVEGAGHNDIELYAQYLERLKQFISHELPNS--------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6PCB6-1", "uniprot_id": "AB17C_HUMAN", "id": "Q6PCB6-1", "name": "Alpha/beta hydrolase domain-containing protein 17C", "aln": "MPEPGPRMNGFSLGELCWLFCCPPCPSRIAAKLAFLPPEPTYTVLAPEQRGAGASAPAPAQATAAAAAAQPAPQQPEEGAGAGPGACSLHLSERADWQYSQRELDAVEVFFSRTARDNRLGCMFVRCAPSSRYTLLFSHGNAVDLGQMCSFYIGLGSRINCNIFSYDYSGYGVSSGKPSEKNLYADIDAAWQALRTRYGVSPENIILYGQSIGTVPTVDLASRYECAAVILHSPLMSGLRVAFPDTRKTYCFDAFPSIDKISKVTSPVLVIHGTEDEVIDFSHGLAMYERCPRAVEPLWVEGAGHNDIELYAQYLERLKQFISHELPNS--------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZVZ7-1", "uniprot_id": "AB17C_DANRE", "id": "Q7ZVZ7-1", "name": "Alpha/beta hydrolase domain-containing protein 17C", "aln": "MPEQGPRMNSFSLGELCWLFCCPPCPSRIAAKLAFLPPEPTYSVHT---------------DP--------------------SGATSLHLTERADWQYSQRELDAVEVLVTRTSRGNRVGCMFVRCAPASRYTLLFSHGNAVDLGQMCSFYIGLGSRINCNVFSYDYSGYGVSTGKPSEKNLYADIEAAWQVLRNKYGVTPENIILYGQSIGTVPTVDLASRYECAAVILHSPLMSGLRVAFPDTRKTYCFDAFPSIDKVSKVASPVLVIHGTEDEVIDFSHGLAIYERCPRAVEPLWVEGAGHNDIELYAQYLERLKQFITFELATS--------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A4D6K2Q0-1", "uniprot_id": "A0A4D6K2Q0_DROME", "id": "A0A4D6K2Q0-1", "name": "palmitoyl-protein hydrolase", "aln": "---------MFSISELCCMFCCPPCPGPIAAKLAFQPPEPTYKLTPADDT---------------------------------NIRYNLQLFDRAEWQYSEREKSKVEAFFTRTSRGNLITCIYVRCSKNAKYTLLFSHGNAVDLGQMSSFYLTLGSQINCNIFGYDYSGYGMSGGKPSEKNLYADIEAAWQAMRTRFNISPETIILYGQSIGTVPTVDLASRHEVGAVILHSPLMSGLRVVFRNTKRTWFFDAFPSIDKVAKVKAPVLVIHGTDDEVIDFSHGIGIYERCPKTVEPFWVEGAGHNDVELHPHYYERLRKFLSVELVKXQLKNNVDGGVSDTTSGVISNSNPAAGSASLSSKHPNPAPAAGSETSKKNVDTNVKRIENDGL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **:.*** :*******. ******* ******.: . .*:* :**:****:** . **.:.:**:*.* : *::***: ::****************.***: ***:****:*.*******:* ************:****.:*.::.::**.*******************:* .**************.* :*::*: *********::** :********:*********:.:*****::***:*********:**:.:* ***::*:: ** . ", "identical_positions": 190, "similar_positions": 67, "identity": "48.59%" }, { "cls_id": "homologset.agr.RGD:1308211", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q80YG3-1", "uniprot_id": "KLDC1_MOUSE", "id": "Q80YG3-1", "name": "Kelch domain-containing protein 1", "aln": "MADPQAFCVAEERSGHCAVVDGHFLYVWGGYVSIEDNEVYLPNDEMWTYDIDSGLWKMHLMEGELPPSMSGSCGACIHGRLYVFGGYDDKGYSNRLYFVNLRTRDGTYTWEKITKFDGQPPTPRDKLSCWVYKDRLIYFGGYGYRRHSELQECFDVHDASWEEQIFWGWHNDVHVFDTKTRTWSQPEIKGGVPPQPRAAHSCAVLGNKGYVFGGRVLQTRMNDLHYLNLDTWVWSGRISVNGESPKHRSWHTLTAITDDKLFLFGGLNADNIPLSDGWIHNITTNCWKQLRHLPYTRPRLWHTACLGKENEIMVFGGSKDNLLFLDTGHCNDLLIFQTQPYSLLRSCLDCIGKNAIILKSQISLLPPKLLQQVLKKITFWTAANYRKEQRIRKEETENNQPRVSSC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2KAE3-1", "uniprot_id": "A0A0G2KAE3_RAT", "id": "A0A0G2KAE3-1", "name": "Kelch domain-containing protein 1", "aln": "MADSQAFCVAEERSGHCAVVDGHFLYVWGGYVSIEDNEVYLPNDEIWTYDVDSGLWKMHLMEGELPPSMSGSCGACINGRLYVFGGYDDKGYSNRLYFVDLRTRDGTYIWEKITKFEGQPPTPRDKLSCWVYKDRLIYFGGYGYRRHSELQECFDVHDASWEEQIFWGWHNDVHVFDTKTRTWSQPEIKGGVPPQPRAAHSCAVLGNKGYVFGGRVLQTRMNDLHYLNLDTWVWSGRISVNGESPKHRSWHTLTAIADDKLFLFGGLSADNIPLSDGWIHNIITNCWKQLRHLPYTRPRLWHTACLGKENEIMVFGGSKDNLLFLDTGHCNDLLIFQTQPYSLLRSCLDCIGKNAIILKSQISLLPPKLLQQVFQKITFWTAANYRKEQRIQKGETENKQPRVSSC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N7A1-1", "uniprot_id": "KLDC1_HUMAN", "id": "Q8N7A1-1", "name": "Kelch domain-containing protein 1", "aln": "MADSQLFCVAEERSGHCAVVDGNFLYVWGGYVSIEDNEVYLPNDEIWTYDIDSGLWRMHLMEGELPASMSGSCGACINGKLYIFGGYDDKGYSNRLYFVNLRTRDETYIWEKITDFEGQPPTPRDKLSCWVYKDRLIYFGGYGCRRHSELQDCFDVHDASWEEQIFWGWHNDVHIFDTKTQTWFQPEIKGGVPPQPRAAHTCAVLGNKGYIFGGRVLQTRMNDLHYLNLDTWTWSGRITINGESPKHRSWHTLTPIADDKLFLCGGLSADNIPLSDGWIHNVTTNCWKQLTHLPKTRPRLWHTACLGKENEIMVFGGSKDDLLALDTGHCNDLLIFQTQPYSLLRSCLDCIGKNSIMLESQISLLPPKLLQQVLKKITFWAAANHREEQRVQKEETENKYQWISSN", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***.* ****************:**********************:****:*****:*********.**********:*:**:****************:***** ** *****.*:************************** *******:**********************:*****:** ****************:*********:*********************.*****::**************.*:****** ***.*************: ******* *** *************************:** ******************************:*:*:**************::*****:***:*:***::* ****: :** ", "identical_positions": 354, "similar_positions": 37, "identity": "87.19%" }, { "cls_id": "homologset.agr.RGD:1308212", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q80XH4-1", "uniprot_id": "WSCD1_MOUSE", "id": "Q80XH4-1", "name": "Sialate:O-sulfotransferase 1", "aln": "MAKPFFRLQKFLRRTQFLLLFLTAAYLMTGSLLLLQRARVALPQALRAPGSLQALPVATVALGVGLLDGRSLRDPHSSPDLLLDVDTLRSPLARLPPGIRWPRRNRS---SLRRRWLHHLTSDPQGPPTLSPEASGPANHNRGNYLGCFSEEGQERTLKGAVFYDLRKMTVSHCQDACAERSYVYAGLEAGAECYCGNRLPATRVSLKECNQECKGEKGSMCGAVRRLSVYSVGLQQPGSKKRRTATYRGCFPLPENVTHTFSSSMTQANMTVETCSGFCSQKEFPLAILRGWDCYCAYPTPQFSLRDAVDGALCSQAPETQGLP----GYCEVYQTPVQDTRCTDRKFLPDKSKVFVALSSFPGAGNTWARHLIEHATGFYTGSYYFDGTLYNKG---FKGEKDHWRSRRTICVKTHESGRREIEMFDSAILLIRNPYRSLVAEFNRKCAGHLGYAPDRNWKSKE---WPEFVNSYASWWSSHVLDWLK----------YGKRLLVVHYEELRHSLVPTLREMVAFLN-VSVSEERLLCVENNKEGSFRRRGRRPHDQEPFTPEMK--DLINGYIRTVDQALRDHNWAGLPREYVPR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q505J3-1", "uniprot_id": "WSCD1_RAT", "id": "Q505J3-1", "name": "Sialate:O-sulfotransferase 1", "aln": "MAKPFFRLQKFLRRTQFLLLFLTAAYLMTGSLLLLQRARVALPQALRAPGSLQALPVATVALGVGLLDSRSLHDPHSSPDLLLDVDTLRSPLARVPPGIRWPRRNRS---SLRRRWLHHLTSDPQGPPTLGPEASGPASHNQGNYLGCFSEEGQERTLKGAVFYDLRKMTVSHCQEACAERSYVYAGLEAGAECYCGNRLPATRVSLKECNQECKGEKGSMCGALHRLSVYSVGLQQSGAKKRWTATYRGCFPLPENITRTFSSSMTQANVTVETCSGFCSQKEFPLAILRGWACYCAYPTPQFSLRDAVDGALCSQGTEAQGLP----GYCEVYQTPVQDTRCTDRKFLPNKSKVFVALSSFPGAGNTWARHLIEHATGFYTGSYYFDGTLYNKG---FKGEKDHWRSRRTICVKTHESGRREIEMFDSAILLIRNPYRSLVAEFNRKCAGHLGYAPDRNWKSKE---WPDFVNSYASWWSSHVLDWLK----------YGKRLLVVHYEELRHSLVPTLREMVAFLN-VSVSEERLLCVENNKEGSFRRRGRHPHDQEPFTPEMK--DLINGYIRTVDQALRDHNWAGLPREYVPR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q658N2-1", "uniprot_id": "WSCD1_HUMAN", "id": "Q658N2-1", "name": "Sialate:O-sulfotransferase 1", "aln": "MAKPFFRLQKFLRRTQFLLFFLTAAYLMTGSLLLLQRVRVALPQGPRAPGPLQTLPVAAVALGVGLLDSRALHDPRVSPELLLGVDMLQSPLTRPRPGPRWLRSRNSELRQLRRRWFHHFMSDSQGPPALGPEAARPAIHSRGTYIGCFSDDGHERTLKGAVFYDLRKMTVSHCQDACAERSYVYAGLEAGAECYCGNRLPAVSVGLEECNHECKGEKGSVCGAVDRLSVYRVDELQPGSRKRRTATYRGCFRLPENITHAFPSSLIQANVTVGTCSGFCSQKEFPLAILRGWECYCAYPTPRFNLRDAMDSSVCGQDPEAQRLA----EYCEVYQTPVQDTRCTDRRFLPNKSKVFVALSSFPGAGNTWARHLIEHATGFYTGSYYFDGTLYNKG---FKGEKDHWRSRRTICVKTHESGRREIEMFDSAILLIRNPYRSLVAEFNRKCAGHLGYAADRNWKSKE---WPDFVNSYASWWSSHVLDWLK----------YGKRLLVVHYEELRRSLVPTLREMVAFLN-VSVSEERLLCVENNKEGSFRRRGRRSHDPEPFTPEMK--DLINGYIRTVDQALRDHNWTGLPREYVPR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TX41-1", "uniprot_id": "A0AB32TX41_DANRE", "id": "A0AB32TX41-1", "name": "", "aln": "MAKPSYRLQHFLRQAHLLLFFLGVAYIMAGSVLLLQRSSVVTFQRDTETVALPSLPAPPRALEGPAVRWLYRRNIIQEMENLDHTDNRNDQKHLITPNLEIR--------HLRRHWFH---SSAEQKSFSEHHLLQKEARQKGTYIGCFINNETEHALGGTILYDFRKMTSTLCQDTCSESGFRYAGLEFGSECHCGNRVCARRARGEDCNLDCRGEKGSPCGGVGRMSVYRVEDRLPGQRRYRTVHYHGCYKRPKNSTADLLIHTSGPTHTPQQCIESCTDQDLPLALLRGQDCFCRRASFLLTIQMSENDQMCKKANQTNQTSLHDLDFYWVYSTPVLDATCKERSFLAQKSSALVALSSFPGAGNTWLRHLIELVTGFYTGSYYFDGSLYNKG---FKGEKDYWQSGRVVCVKTHESGQREIQMFDSAILLMRNPYRSLMAEFNRKCAGHLGYASHAHWRSKE---WSEFVDSYSSWWVSHALAWLR----------FAHRLLVVHFEDLQKDVVPQIKTVTAFLN-ISIPEERLLCIESDRDGHFKRSGSHNLNFDPFSPEMR--ARIDQYIQTVDKALRDRNHSGLPHQYMPR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VXV9-1", "uniprot_id": "WCSD_DROME", "id": "Q9VXV9-1", "name": "WSCD family member CG9164", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MALQGWRFFGVSATIIIYIG--------------------------GVLFLSMNNIPGSHPKRPRIERFAEFPSFHSPR----------------------------------------FPMPSRKMTIRWCRDLKYINRDLP----------IYADYKSDFYTALPSDVSAALQSLPALTALASFPGSGNTWLRYLLQQATGILTGSIYKDYGLLKTG---FPAEN--VCNSSVLLVKTHEWGSKAWAPFSKAILLVRDPEKAIIAEFNRQSGGHIGFASPDRYKRTKGKYWQQFVSNKLKGWEMMNLSWARN---------FTGSIKVVFYDDLVHHTERELRSILDFLQ-FPINEQLMRCAIMRKEGIFRRK-KRLLSFDPYTESMR--AEVQNRRRIVYGLLGRQEP----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12215-1", "uniprot_id": "WSC3_YEAST", "id": "Q12215-1", "name": "Cell wall integrity and stress response component 3", "aln": "MERVWFAKLTNKGTIKIGYISFILLSLLCQSLIGLVNADFNYEGCYSAADIQSAGLSLKNSYIYQSVSYCQNQCPESAVVALFNGSDCYCGNSVS--------------------FLTSLTKSTDSNCGTKCSGWPYQMCGGSSYMNVYVNAET-----------FVSSVESSSSKEGSSTSYMPSTTSSLSSAQISSTTRRTSTDMKSSEMIATTVSTTSTTSSSTSSTTSSTTSSTTSSTTSSTTSSSTSSTTSSTTSSTTSSTTSSTTSSTTSSTTSSTTSSTTSIFS-----VTSSSSSITLSSSEHTTVDSRTSSPSS------TLVPVSSSSSTLSTPKVTSMTPSTSSTIPIVTSVELVTSVVTKAIVSTSDQHQETIFVTRTSVVERSSEVATATAAASNNRSNSTSKQRLSGGAIAGIVIGVVFGVIFIILILLFLIWRRRKSHDQLDLEETKHYQPYSFGDEDANPIGPPPSSGTTNWMRHSRGNTAGSIGTSNMYGFSMSNGANYSSPSSNTSGSIINNLAGLQDATVQKQNLPSTVFEEANTLNSANERFSANSLPDMMMSGPLQVVNPDNPDNPELSSTVSHNRA", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .: . . . * . . .: :.: . . : .: : . .. .: ::*. .. : ::. : : . . . * : * . .:: : :: : *: .* : : .. * : : . .: . . ::: .. :: . *.. : :: . :. : * . ", "identical_positions": 9, "similar_positions": 78, "identity": "1.51%" }, { "cls_id": "homologset.agr.RGD:1308213", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZR45-1", "uniprot_id": "A0A8I5ZR45_RAT", "id": "A0A8I5ZR45-1", "name": "Pre-B-cell leukemia transcription factor 1", "aln": "MDEQPRLMHSHAGVGMAGHPGLSQHLQDGAGGTEGEGGRKQDIGDILQQIMTITDQSLDEAQARKHALNCHRMKPALFNVLCEIKEKTVLSIRGAQEEEPTDPQLMRLDNMLLAEGVAGPEKGGGSAAAAAAAAASGG-----AGSDNSVEHSDYRAKLSQIRQIYHTELEKYEQ----ACNEFTTHVMNLLREQSRTRPISPKEIERMVSIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNFNKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKKNIGKFQEEANIYAAKTAVTATNVSAHGSQANSPSTPNSAGSSSSFNMSNSGDLFMSVQSLNGDSYQGAQVGANVQSQVDTLRHVISQTGGYSDGLAASQMYSPQGISANGGWQDATTPSSVTSPTEGPGSVHSDTSN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P41778-1", "uniprot_id": "PBX1_MOUSE", "id": "P41778-1", "name": "Pre-B-cell leukemia transcription factor 1", "aln": "MDEQPRLMHSHAGVGMAGHPGLSQHLQDGAGGTEGEGGRKQDIGDILQQIMTITDQSLDEAQARKHALNCHRMKPALFNVLCEIKEKTVLSIRGAQEEEPTDPQLMRLDNMLLAEGVAGPEKGGGSAAAAAAAAASGG-----AGSDNSVEHSDYRAKLSQIRQIYHTELEKYEQ----ACNEFTTHVMNLLREQSRTRPISPKEIERMVSIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNFNKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKKNIGKFQEEANIYAAKTAVTATNVSAHGSQANSPSTPNSAGSSSSFNMSNSGDLFMSVQSLNGDSYQGAQVGANVQSQVDTLRHVISQTGGYSDGLAASQMYSPQGISANGGWQDATTPSSVTSPTEGPGSVHSDTSN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P40424-1", "uniprot_id": "PBX1_HUMAN", "id": "P40424-1", "name": "Pre-B-cell leukemia transcription factor 1", "aln": "MDEQPRLMHSHAGVGMAGHPGLSQHLQDGAGGTEGEGGRKQDIGDILQQIMTITDQSLDEAQARKHALNCHRMKPALFNVLCEIKEKTVLSIRGAQEEEPTDPQLMRLDNMLLAEGVAGPEKGGGSAAAAAAAAASGG-----AGSDNSVEHSDYRAKLSQIRQIYHTELEKYEQ----ACNEFTTHVMNLLREQSRTRPISPKEIERMVSIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNFNKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKKNIGKFQEEANIYAAKTAVTATNVSAHGSQANSPSTPNSAGSSSSFNMSNSGDLFMSVQSLNGDSYQGAQVGANVQSQVDTLRHVISQTGGYSDGLAASQMYSPQGISANGGWQDATTPSSVTSPTEGPGSVHSDTSN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QFI5-1", "uniprot_id": "A0A8M9QFI5_DANRE", "id": "A0A8M9QFI5-1", "name": "Pre-B-cell leukemia transcription factor 1", "aln": "MDEQPRLMHAHAAVGMSGHPGLAPHIPDNTGAADGDG-RKQDIGDILQQIMTITDQSLDEAQARKHALNCHRMKPALFNVLCEIKEKTVLSIRGAQEEEPPDAQLMRLDNMLLAEGVSGPEKGGGSAAAAAAAAASGG-----VGADNSAEHSDYRAKLSQIRQIYHTELEKYEQVSKHACNEFTTHVMNLLREQSRTRPISPKEIERMVGIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNFNKQATEILNEYFYSHLSNPYPSEEAKEELAKKCSITVSQVSNWFGNKRIRYKKNIGKFQEEANMYAARTAVNAASVSAHGSQANSPSTPNSAGSAGSFNMSNSGDLFMSVQSLNGDSYQGSQVGANVQSQVDTLRHVISQTGGYSDGLAANQMYSPQGINANGGWQDPTTPSSVTSPTEGPGSVHSDTSN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P40427-1", "uniprot_id": "EXD_DROME", "id": "P40427-1", "name": "Homeobox protein extradenticle", "aln": "MEDPNRMLAHTGGMMAPQGYGLSGQDDGQNAGSENEVRKQKDIGEILQQIMSISEQSLDEAQARKHTLNCHRMKPALFSVLCEIKEKTVLSIRNTQEEEPPDPQLMRLDNMLIAEGVAGPEKGGGGAAAASAAAASQGGSLSIDGADNAIEHSDYRAKLAQIRQIYHQELEKYEQ----ACNEFTTHVMNLLREQSRTRPITPKEIERMVQIIHKKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNFSKQASEILNEYFYSHLSNPYPSEEAKEELARKCGITVSQVSNWFGNKRIRYKKNIGKAQEEANLYAAKKAAGASPYSMAGPPSGT-TTP-----------------MMSPAPPQDS--MGYPMGS----------------GGYDQ----QQPYD----NSMGGYDP---------------NLHQDLSP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:: *:: ..: . **: : . ..::.: :::***:******:*::***********:***********.**************.:*****.*.*********:****:*******.****:***** * *:**: *********:******* ******* **********************:******** ***:**********************************.***:*************************:**.*********************** *****:***:.*. *: * *. :.: :** :** . :.. * :*: ***.: .* *. .: **:: .:*.* * ", "identical_positions": 260, "similar_positions": 71, "identity": "59.23%" }, { "cls_id": "homologset.agr.RGD:1308214", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q498S0-1", "uniprot_id": "Q498S0_RAT", "id": "Q498S0-1", "name": "Carbohydrate sulfotransferase", "aln": "MTKPRLFRLWLALGSALMIL-LIIVYWDNVGTAHFYLHTSLSRPHILEPLPTQG--LAEENVLASDVDEFLDTLLSSDAKHNDLSRRKTEQPPVLTPSKPVLSHMEENVRGYDWSTHDAQQNPDRDRQQAERRSLLRDFC-ANASLAFPTKDRSFDDIPNYELNHLIVDDRHGVIYCYVPKVACTNWKRVMIVLSESLLD-RGSPYRDPLDIPREHVHNTSTHLTFNKFWRRYGKFSRHLMKVKLKKYTKFLFVRDPFVRLISAFRSKFELENEEFYRKFAVPMLRLYANHTSLPASVSEAFSAGLKVSFANFIQYLLDPHTEKLAP--FNEHWRQVYRLCHPCQIDYDFVGKLETLDEDAAQLLRSLKVDSQLHFPPSYRNRTASSWEEDWFANIPLAWRQQLYKLYEADFVLFGYPKPENLLRD--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99LL3-1", "uniprot_id": "CHSTC_MOUSE", "id": "Q99LL3-1", "name": "Carbohydrate sulfotransferase 12", "aln": "MTKPRLFRLWLVLGSALMIL-LIIVYWDNVGTAHFYLHTSLSRPHILEPLPTQG--LVEENVFTSDVDEFLDTLLSSDAKHNDLSRRKTEQPPVPAPSKPVLSHMEENVRGYDWSTHDAHQNPDRDRQQAERRSLLRDFC-ANASLAFPTKDRSFDDIPNYELNHLIVDDRHGVIYCYVPKVACTNWKRVMIVLSESLLD-RGSPYRDPLDIPREHVHNTSTHLTFNKFWRRYGKFSRHLMKVKLKKYTKFLFVRDPFVRLISAFRSKFELENEEFYRKFAVPMLRLYANHTSLPASVSEAFSAGLKVSFANFIQYLLDPHTEKLAP--FNEHWRQVYRLCHPCQIDYDFVGKLETLDEDAAQLLRFLKVDSQLHFPPSYRNRTASSWEEDWFANIPLAWRQQLYKLYEADFVLFGYPKPENLLRD--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NRB3-1", "uniprot_id": "CHSTC_HUMAN", "id": "Q9NRB3-1", "name": "Carbohydrate sulfotransferase 12", "aln": "MTKARLFRLWLVLGSVFMIL-LIIVYWDSAGAAHFYLHTSFSRPHTGPPLPTPGPDRDRELTADSDVDEFLDKFLSAGVKQSDLPRKETEQPPAPG-------SMEESVRGYDWSPRDARRSPDQGRQQAERRSVLRGFC-ANSSLAFPTKERAFDDIPNSELSHLIVDDRHGAIYCYVPKVACTNWKRVMIVLSGSLLH-RGAPYRDPLRIPREHVHNASAHLTFNKFWRRYGKLSRHLMKVKLKKYTKFLFVRDPFVRLISAFRSKFELENEEFYRKFAVPMLRLYANHTSLPASAREAFRAGLKVSFANFIQYLLDPHTEKLAP--FNEHWRQVYRLCHPCQIDYDFVGKLETLDEDAAQLLQLLQVDRQLRFPPSYRNRTASSWEEDWFAKIPLAWRQQLYKLYEADFVLFGYPKPENLLRD--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PZ65-1", "uniprot_id": "A0A8M1PZ65_DANRE", "id": "A0A8M1PZ65-1", "name": "Carbohydrate sulfotransferase", "aln": "--MQKLHHFCFLLGAVFITLFFIVVFWDEVRVG----TYQHMD-----------------------------------------------------------------------SSKNLKQ------RQAHRKHLINKLCLANSSLLFRDKLITFDQIPNKALDHLIVDDRHRVIYCFVPKVACTNWKRVMIVLSQNLKAPDGAPYLHPLDIPIEVIHNSTVHKTFNNLWIHHGRYARPLMHQKLKNYTKFLFVRDPFVRLISAFRAKFNRPDEYFYSNYGSTMLQRYANISHPPASAQEAFSAGIRLSFTHFIQYLLDPQTEKEKP--FNEHWQQIHRLCHPCQIDYDFIGKLETLDEDTEHLLKILGLDKHIHFPPGNENRTAVDWEREWFANISVAHRRKLYSLYETDFKLFGYDKPETLLNE--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1Q1N4-1", "uniprot_id": "A0A8M1Q1N4_DANRE", "id": "A0A8M1Q1N4-1", "name": "Carbohydrate sulfotransferase", "aln": "--MQKLHRHCLLLGAVFITMSFIVVFWDEVRVGPPYPRTNHRA-----------------------------------------------------------------------SSKHLAQF---KLRQAHRKHLIKELCSANSSLNYRQKSIT--------LDHLIVDDHHRVIYCYVPKVACSNWKRVMFVLSQNLKAPDGAPYLDPLDIPLEIIHNSTVHNTFKKLWMRHGRYARPLMHQKLKNYTKFLFVRDPFVRLISAYRDKFAEPNEYYYYKFGFMILQRYANISQPPTLAPEAFRAGIRPSFSHFIKFLLDPQTEKEKP--FDEHWKQIHRLCHPCQIDYDFIGKLETLDEDTEHLLKILGLDKHIHFPPGYENRTAVDWEQEWFANISLADRRELYSLYETDFKLFGYDKPETLLNE--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VJG5-1", "uniprot_id": "Q9VJG5_DROME", "id": "Q9VJG5-1", "name": "Carbohydrate sulfotransferase", "aln": "--MDQLVWLSFCISIGFSLLGNFSTGLPFEDGNNNNVKITRRS-----------------------------------------------------------------------------------LELTQTINIQRQEFMQRQCELLGDHTQTLEDLSELQMDHMIVDKEHKLLYCYVPKVACTNWKRVLMMLTNKWHN-----GTDPLQIPGSLAHSVGMFTKLYDLSEAE------QQQVLSDEYTRFILVRHPLERLLSAYRNKLE--GDSPSARYFQSRVGRQIVKELRPGASNNSLERGDDVSFGEFIQYLVTPELSRANQSDYNEHWEVIAKLCNPCVMKYNVVGKYDTLLDDSALALYLAGADN-LTFPTGHKPSSTRANLRNYFDPLPIGAIRKLYDIYEDDFRLFDYALDEVLGFEFG", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* : :. : : : . . :. : . . . : : :.*:***..* :**:******:*****:::*: . .** ** . *. . .: .: : .:**:*::**.*: **:**:* *: .: .: : * ::: * ** .**::*: *. .: ::***. : :**:** :.*:.:** :** :*: * * : **.. . :: .::* :.:. ::**.:** ** **.* * * : ", "identical_positions": 74, "similar_positions": 97, "identity": "17.29%" }, { "cls_id": "homologset.agr.RGD:1308215", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M6Q7-1", "uniprot_id": "A0ABK0M6Q7_RAT", "id": "A0ABK0M6Q7-1", "name": "", "aln": "--------------------------------------------------------------------------------------MLTPMVAGGVVFPGLFLLSKNTLQRLPQ-------LRWEEADAVIVSARLVSSVQAIMASTAGYIVSTS--CKHIIDDQHWLSSAYTQFAVPYFIYDIYAMFLCHWHKHQVKGHGG----EDGTPRALGSTWAVVRG--------------------------------------YLHKEFLMVLHHAAMVLVCFPLSVVWRQGKGDFFLGCMLMAEVSTPFVCLGKILIQYKQQHTLLHKVNGALMLLSFLCCRVLLFPYLYWAYGRHAGLP-LLSVPMAIPAHVNLGAALLLAPQLYWFFLICRGACRLFRPRGSPPRSPCQTQD------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TNV1-1", "uniprot_id": "TLC3B_MOUSE", "id": "Q7TNV1-1", "name": "Ceramide synthase", "aln": "--------------------------------------------------------------------------------------MLTPMVAGGVVFPGLFLLSKNTLQRLPQ-------LRWEEADAVIVSARLVSSVQAIMASTAGYIVSTS--CKHIIDDQHWLSSAYTQFAVPYFIYDIYAMFLCHWHKHQVKGHGG----EDGTPRALGSTWAVVRG--------------------------------------YLHKEFLMVLHHAAMVLVCFPLSVVWRQGKGDFFLGCMLMAEVSTPFVCLGKILIQYKQQHTLLHKVNGALMLLSFLCCRVLLFPYLYWAYGRHAGLP-LLSVPMAIPAHVNLGAALLLAPQLYWFFLICRGACRLFRPRGSPPPSPCQTQD------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q71RH2-1", "uniprot_id": "TLC3B_HUMAN", "id": "Q71RH2-1", "name": "Ceramide synthase", "aln": "--------------------------------------------------------------------------------------MLTPMVAGGVVFPGLFLLSKNTLQRLPQ-------LRWEEADAVIVSARLVSSVQAIMASTAGYIVSTS--CKHIIDDQHWLSSAYTQFAVPYFIYDIYAMFLCHWHKHQVKGHGG----DDGAARAPGSTWAIARG--------------------------------------YLHKEFLMVLHHAAMVLVCFPLSVVWRQGKGDFFLGCMLMAEVSTPFVCLGKILIQYKQQHTLLHKVNGALMLLSFLCCRVLLFPYLYWAYGRHAGLP-LLAVPLAIPAHVNLGAALLLAPQLYWFFLICRGACRLFWPRSRPPP-ACQAQD------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BBE5-1", "uniprot_id": "A0A8M2BBE5_DANRE", "id": "A0A8M2BBE5-1", "name": "", "aln": "--------------------------------------------------------------------------------------MLSILAAGSIFFPGLFLLSKRFLKHAPG-------LKWSEKDAVIVSSRLVSSVQAIMASSAGYIIACS--CKDIIEDQHWLTTSYILFAVPYFVYDIYAMFLCYWYKLQVKDHEE----ESETK----PMRSAIRG--------------------------------------YLHREFLMVLHHVVMVTVCFPVSVFWRQGKGDYFQGVMFLAELSTPSVCLGKILIQYKQQHTLLHKVNGALMLVTFFICRVVLFPYLYYAYGRYASIP-FYMVPLSVPWQCNVGAALLMAPQVYWFSLICRGAFRLFTGASRH-KAPISNTDSEPKSSLLPPANGYSPRETDSH--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ACD6B5W6-1", "uniprot_id": "A0ACD6B5W6_DANRE", "id": "A0ACD6B5W6-1", "name": "", "aln": "--------------------------------------------------------------------------------------MLSIIAAGSVFFPGLFLLSKQMLRCIPG-------LQWNEGDATIVSARLVSSIQAIMASTAGYIISSS--CQDIIEDQHWLTSSYILFAVPYFVYDIYAMFLCYWHKLQVKGHEV----DNGSR----SKAMAIAG--------------------------------------YLRREFLMVLHHVVMVTVCFPVSVFWRQGKGDYIQGVMFLAELSTPSVCLGKILIQYKQQHTLLHKVNGAVMLITFFLCRVLLFPYLYYIYGRYASIP-FYLVPFSVPWQCNLGASLLMAPQVYWFSLICRGALRLFTGRSSHSRKPPVKPDCEGHETANGYSTRMVGRDTPTMAH", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V3S7-1", "uniprot_id": "Q9V3S7_DROME", "id": "Q9V3S7-1", "name": "TLC domain-containing protein", "aln": "MQQRRQPANGNGRGGGTTAAVRTEEQQQQQQPLSQDAGAKEAGSTPGKATGRGCYFSLAFSIGSMGLACGSLWQIPNSSDRISLQRGLVLTSLGFIYFVSLTDFCNKYLLETTHGQRFRRKYRLMMSDVLEITNKIVSAIQASFSFFVGLIVCKSTCTKSFVYASHFLMEAYGWFGTAYFMYDIWSMYKVHTQKIADKLHLLRITKGQGAVVSNGHANGKVNGKSASGNNNGSTPTNLHEICDYDGACVQIPKDGRWDFLKYVVTHPVMMIHHVFIGTFGLLVVTYIRGG-GHCIYSYMFMMEFSTPFVSLRSILSTMRLKDSRVYIANGLLMLATFFVCRVCMWPYVMWRYSLAIEAASLWSAMWGLPRGCLISIAILFLPQLYWFYLMVLGALKVFLPQKRRPPNAVLSAKSAAVPTPTPTALINGKN-------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * : * .* :.:. * . : *. :: ::**::** :: .* *:. * : :: .*:* :* *...**:***::*: : * * * . : * *: . :*::**. : . : : . * * *. : . *:: *.*** *.* .** : :.: :: .** :** :*: *** ::**: : *. . : . .:* :. ::*: **:*** *: ** ::* . . ", "identical_positions": 65, "similar_positions": 86, "identity": "14.87%" }, { "cls_id": "homologset.agr.RGD:1308216", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A942-1", "uniprot_id": "A0A8I6A942_RAT", "id": "A0A8I6A942-1", "name": "Ubiquitin carboxyl-terminal hydrolase", "aln": "MQTENPPRPRQTRSLLTMDRCKHIEQLQLAQGHSILNPQKWFCMVCNTTESIWACLSCSHVACGQYIQEHALKHFEESSHPVAFEVNDMYVFCYLCNDYVLNDNTAGDLKSLRSTLSAIKGKSYPCVVQSDSVLQPVNAQADSYSLHDSTQSLPG-SEDPMCTALWHRRRALMGKTFRTWFEQSPIGRKRQE---QTQEKTVAKREVKRRQQ-ELEQQMKAELECTPPRKSLRLQGLS-EAATVEIL---------------PVQAPPPPPASPAKEKALALPPSEDGK------LKRVSDSLIKRRPAVTPGVTGLRNLGNTCYMNSVLQVLSHLLIFRQCFLKLDLNQWLAVAASDKARSYKHSAVTDAATAAAHQLNEGQEKEKGFACSRHPGLSSGLSGGASKGRNMELIQPREPSSPYSSLCHELHTLFQVMWSGEWALVSPFAMLHSVWKLIPAFRGYAQQDAQEFLCELLDKIQRELETTGTKLPALIPTSQRRLIEQVLNVVNNIFHGQLLSQVTCLACNNKSNTIEPFWDLSLEFPERYQCSGKDAASQPCLVTDMLGKFTETEALEGKIYVCDHCNSKRRKFSSKPVVLTEAQKQLMICHLPQVLRLHLKRFRWSGRNNREKIGVHVVFEETLNMEPYCCSETLNALRPECFIYNLSAVVIHHGKGFGSGHYTAYCYNSEGGFWVHCNDSKLSMCTMEEVLRAQAYILFYTQRVTENGHSRLLPPELLSNSQQHPSEETDTSSNEVLS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C2S0-1", "uniprot_id": "UBP44_MOUSE", "id": "Q8C2S0-1", "name": "Ubiquitin carboxyl-terminal hydrolase 44", "aln": "-----------------MDRCKHVEQLQLAQGHSILDPQKWYCMVCNTTESIWACLSCSHVACGKYIQEHALKHFQESSHPVAFEVNDMYAFCYLCNDYVLNDNAAGDLKSLRSTLSTIKSKKYPCVVPSDSVLHPVDAQDRVYSLLDGTQSLPG-NEDPTCAALWHRRRVLMGKAFRTWFEQSAIGRKGQE---PTQERMVAKREAKRRQQQELEQQMKAELESTPPRKSLRLQGSSEEAATIEIV---------------PVRAPPPPPASPAKDKA-ALPTSEDRT------FKKVSDSLIKRRPMVTPGVTGLRNLGNTCYMNSVLQVLSHLLIFRQCFLKLDLNQWLAVAASDKARSYKHSAVTEAA---AQQMNEGQEKEKGFVCSRHSGLSSGLSGGASKGRNMELIQPREPSSPYSSLCHELHILFQVMWSGEWALVSPFAMLHSVWRLIPAFRGYAQQDAQEFLCELLDKIQRELETTGTKLPALIPTSQRRLIEQVLNVVNNIFHGQFLSQVTCLACDNKSDTIESFWDLSLEFPERYQCSGKDAASQPCLVTDMLDKFTETEALEGKIYMCDHCNSKRRKFSSKSVVFTEAQKQLMICHLPQVLRLHLKRFRWSGRNNREKIGVHVVFEETLNMEPYCCRETLNALRPECFLYNLSAVVIHHGKGFGSGHYTAYCYNSEGGFWVHCNDSKLSMCTMEEVRKAQAYILFYTQRVTENGHSKLLPPELLSNSQ-HPSKETDASSNEVLS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H0E7-1", "uniprot_id": "UBP44_HUMAN", "id": "Q9H0E7-1", "name": "Ubiquitin carboxyl-terminal hydrolase 44", "aln": "--------------MLAMDTCKHVGQLQLAQDHSSLNPQKWHCVDCNTTESIWACLSCSHVACGRYIEEHALKHFQESSHPVALEVNEMYVFCYLCDDYVLNDNTTGDLKLLRRTLSAIKSQNYHCTTRSGRFLRSMGTGDDSYFLHDGAQSLLQ-SEDQLYTALWHRRRILMGKIFRTWFEQSPIGRKKQEE--PFQEKIVVKREVKKRRQ-ELEYQVKAELESMPPRKSLRLQGLA-QSTIIEIV---------------SVQVPAQTPASPAKDKV--LSTSENEI------SQKVSDSSVKRRPIVTPGVTGLRNLGNTCYMNSVLQVLSHLLIFRQCFLKLDLNQWLAMTASEKTRSCKHPPVTDTV---VYQMNECQEKDTGFVCSRQSSLSSGLSGGASKGRKMELIQPKEPTSQYISLCHELHTLFQVMWSGKWALVSPFAMLHSVWRLIPAFRGYAQQDAQEFLCELLDKIQRELETTGTSLPALIPTSQRKLIKQVLNVVNNIFHGQLLSQVTCLACDNKSNTIEPFWDLSLEFPERYQCSGKDIASQPCLVTEMLAKFTETEALEGKIYVCDQCNSKRRRFSSKPVVLTEAQKQLMICHLPQVLRLHLKRFRWSGRNNREKIGVHVGFEEILNMEPYCCRETLKSLRPECFIYDLSAVVMHHGKGFGSGHYTAYCYNSEGGFWVHCNDSKLSMCTMDEVCKAQAYILFYTQRVTENGHSKLLPPELLLGSQ-HPNEDADTSSNEILS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZUM8-1", "uniprot_id": "UBP44_DANRE", "id": "Q7ZUM8-1", "name": "Ubiquitin carboxyl-terminal hydrolase 44", "aln": "-----------------MDRCKHVGRLRLAQDHSILNPQKWHCVDCNTTESVWACLSCSHVACGRYIEEHALQHFKEQHHPLALEVNELYVYCYLCDDYVLNDNATGDLKLLRSTLSAIKSQCYEVTTRSGRTLRSSSANGD--QLSPSTQELQLRDEDRMFTALWHRRRALIGRLFRLWFAQTERGKKRLEEERQQEEEEERKREARERRR-QLKRQLKEELESAPPRKSHRIRRQSLKATSVKPARAPAKSTKSVRRRSAPARVSTPTPRTPRERTPQQRPRPQAKAKRPQAPPSKTGDSPVKRRPTVTPGVTGLRNLGNTCYMNSILQVLSHLHVFRECFLRLDLNQALELLASAVSRKLGLSAQRVIQ---PKGLNQG----------------SGLSGGASRSRNMELIQPKEPSSKHISLCHELHTLFPVMWSGKWALVSPFAMLHSVWQLIPAFRGYAQQDAQEFLCELLDKVQHELERTRTLTPATVPANQRRLIKQVLSVVNTIFHGQLLSQVRCLACDHRSNTIEPFWDLSLEFPERYHSNSKDAAQVPCGLTEMLAKFTETEALEGAIYACDYCNNKRRRFCSKQVVLTEAQKQLMVHKLPHVLRLHLKRFRWSGRNHREKIGVHVQFEQELNMEPYCCKDSGNLPHPQHFLYQLSAVVMHHGKGFGSGHYTAFCYNTEGGFWVHCNDSKLSVCAVEEVCKAQAYILFYTQRNAQD-----------------KSKESDL-------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** ***: :*:***.** *:****.*: ******:************:**:****:**:*. **:*:***::*.:****:*******::**** ** ***:**.: * .. *. *:. .: * .:*.* .** :******* *:*: ** ** *: *:* * :*. ***.:.*:: :*: *:* ***. ***** *:: : ::: :: ..:... .* :* : . . .: .:..** :**** *******************:******* :**:***:***** * : ** :*. .. :*: ********:.*:******:**:* : ******* ** *****:**************:***********************:*:*** * * ** :*:.**:**:***.***.*****:**** ****:::*:***.************:...** *. ** :*:** ********** ** ** **.***:*.** **:********: :**:***************:******** **: ******** :: : :*: *:*:*****:*************:***:**************:*:::** :*********** ::: .:::* ", "identical_positions": 409, "similar_positions": 150, "identity": "53.96%" }, { "cls_id": "homologset.agr.RGD:1308217", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5PQS3-1", "uniprot_id": "MELT_RAT", "id": "Q5PQS3-1", "name": "Ventricular zone-expressed PH domain-containing protein homolog 1", "aln": "MHQLFRLVLGQKDLSRAGDLFSLDDAEIEDSLTEALEQIKVISSSLDYQTNNNDQAVVEICITRITTAIRETESIEKHARALVGLWDSCLEHNLRPAGKD-EDTPHAKIASDIMSCILQNYNRTPVMVLAVPIAVKFLHRGSKELCRNMSNYLSLAAITKADLLADHTEGIVKSILQGNAMLLRVLPAVYEKQPQPINRHLAELLALMSQLEQTEQYHLLRLLHVAAKRKDVEVVQKCVPFLIRNLKESTYNDIILNILIEIAGHEPLALNSFLPMLKEIAEQFPYLTGQMARIFGAVGHVDEERARSCLRYLVSQLANMEHS--------------FHHILLLEIKSLTDAFSSILGPHSRDIFRMSN-----------------------------------------------------------------------------------------------------------SFTNIAKLLSRQLENS-KAESGRRRTGTEVSFPEKFREPKTMEPKSEDHEKLQVKIQAFEDKIN-------AESHTPGSVRRYSLDHVSKEERKNVRFSRSRSLALNTVLTNSVNV--------EDGEIEGKTGMHASISLSEIDPPGHGIGKVPFKTDTHGSQLRNSSASHPSIIHSEPENMPETFKENVQEEIPEAAISPVEYQDKLYLHLKENLSKVKAYALEIAKKVPIPDQCTIEDN------TRSCVAKLFFTCSLKGHYCLYSKSSFTLVSQAPQPWIQIMFLFQQS----LFPEPLSIQSGSVQFLKALWEKTQGTGTHSFEVAMTESTFPQQKDLDQLQLHLEEVRFFDVFGFSETAGA----------WQCFMCNNPEKAT-VINQDGQPLIEGKLKEKQVRWKFIKRWKTRYFTLAGNQLLFQKGKS-DDPDDSPIELSKVQSVKAVAKKRRDRSLPRAFEIFTDNKTYVFKAKDEKNAEEWLQCINVALAQAKERESREVTTYL-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A1A535-1", "uniprot_id": "MELT_MOUSE", "id": "A1A535-1", "name": "Ventricular zone-expressed PH domain-containing protein 1", "aln": "MHQLFRLVLGQKDLSKAGDLFSLDDAEIEDSLTEALEQIKVISSSLDYQTNNNDQAVVEICITRITTAIRETESIEKHARALVGLWDSCLEHNLRPAGKD-EDTPHAKIASDIMSCILQNYNRTPVMVLAVPIAVKFLHRGSKELCRNMSNYLSLAAITKADLLADHTEGIIKSILQGNAMLLRVLPAVYEKQPQPINRHLAELLALMSQLEQTEQYHLLRLLHVAAKRKDVEVVQKCVPFLIRNLKDSTYNDIILNILIEIAGHEPLALNSFLPMLKEIAEQFPYLTGQMARIFGAVGHVDEERARSCLRYLVSQLANMEHP--------------FHHILLLEIKSITDAFSSILGPHSRDIFRMSN-----------------------------------------------------------------------------------------------------------SFTNIAKLLSRQLENS-KADSSRRKTSTEVSIPEKLRELNSMEPESEDHEKLQVKIQAFEDKIN-------AESNTPGSGRRYSLDHISKEERKSIRFSRSRSLALNTVLTNGVSV--------EDNEVEEKAGMHASISLSQIDPLSHGIGKLPFKTDTHGSPLRNSSASHPSIIHTEPETMPETFKENIQEEILEAATSPIEYQDKLYLHLRENLSKVKAYALEIAKKVPIPDQCTIEDT------MRSCVAKLFFTCSLKGHYCLYSKSSFILVSQAPQPWIQVMFLSQQS----LFPEPLSIQSGSVQFLKALWEKTQDTGAHSFEVAMTESTFPQQKDLEQLQLHLEEVRFFDVFGFSETAGA----------WQCFMCNNPEKAT-VVNQDGQPLIEGKLKEKQVRWKFIKRWKTHYFTLAGNQLLFQKGKSKDDPDDSPIELSKVQSVKAVAKKRRDRSLPRAFEIFTDSKTYVFKAKDEKNAEEWLQCINVALAQAKERESREVTTYL-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14D04-1", "uniprot_id": "MELT_HUMAN", "id": "Q14D04-1", "name": "Ventricular zone-expressed PH domain-containing protein homolog 1", "aln": "MHQLFRLVLGQKDLSRAGDLFSLDDSEIEDSLTEALEQIKIISSSSDYQTNNNDQAVVEICITRITTAIRETESIEKHAKALVGLWDSCLEHNLRPFGKD-EDTPHAKIASDIMSCILQNYNRPPVMALAIPIAVKFLHRGNKELCRNMSNYLSLAAITKADLLADHTEVIVKSILQGNTMLLRVLPAVYEKQPQPINRHLTELLALMSQLEQPEQYHLLRLLHVAAKKKQLEVVQKCIPFLIGHLKDSTHNDIILNILIEIAVYEPVALNSFLPMLKEIGERFPYLTGQMARIYGAVGHVDEERARSCLTYLVSQLANMEHS--------------FHHILLLEIKSITDTFSSILGPQSRDIFRMSN-----------------------------------------------------------------------------------------------------------SFTAIAKLLTRQLENT-KAGSGRRKISTEIEFPEKLEETKLIVTENEDHEKLQVKIQAFEDKIN-------AGSNTPGSIRRYSLGQVSKEERKNIRFNRSKSLAFHTMLTKGVGS--------DDGEDENRGDIPASISLSEIDPLGQGNDKLPFKTDTERSQLGESSVSYPNIIHIDSENLSETVKENSQEETPETTASPIEYQDKLYLHLKKNLSKVKAYAMEIGKKIPVPDQCTIEDT------VRSCVAKLFFTCSLKGHYCLYSKSSFILISQEPQPWIQIMFLFQQS----LFPEPLSIQSHSVQFLRALWEKTQAGGAHSFETAMMESTFPQQKDLDQVQLHLEEVRFFDVFGFSETAGA----------WQCFMCNNPEKAT-VVNQDGQPLIEGKLKEKQVRWKFIKRWKTRYFTLAGNQLLFQKGKSKDDPDDCPIELSKVQSVKAVAKKRRDRSLPRAFEIFTDNKTYVFKAKDEKNAEEWLQCINVAVAQAKERESREVTTYL-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2BID5-1", "uniprot_id": "MELT_DANRE", "id": "A2BID5-1", "name": "Ventricular zone-expressed PH domain-containing protein", "aln": "MHQLFRLVLGQRDLSRAGDLFSLDDSEIEDCLSQALEEIKVISCSPDYLTNDNDQAVVEICITRITTAIRETGSIERHGAALVSLWESCLEHNLQPQGKD-EDTPHAKIASDITSCILQNYNRPPVMALAVPVAVRFLQQGNQELSRNMSSYLSLAAIAKAELLAQHTEAITCSVLAGNTMLLRVLPSVYPRQPEPIHQHVRELTAMMPRLDQTGRQHLLRLLQMIS-DLHPLVLSSLVPLLIGFLGDSDLGDSALGVLVNVAQSSPVSLAPFLSTLRNVGQKNPWLLGHIAKIHRAVGLTSEIQARGALQYLVSLLASMEHS--------------AHHTLLLEIRCLTDRYTSILGGGGKDIYRMSN-----------------------------------------------------------------------------------------------------------SFSAIARLLGRKLEAD-GAVSRGEEKVQDLPRPHEAESGSEMFAEN---LHLQVKIQAFEEKIGDEEVESEVDGASPGPQRRHSLGQAARDERREMRFNRSKSLALHAVRTRSINS--------DSSPEGEGLDLNAELNVCEAET----------------SSVSSTPHNHTELTETQPDTSPNTEGAKVEDGDPRE-------RDRLWIHLRDNMEEIKSFCAEMIKQIPVPEHCVIEDS------HRGCVAKLSFSCPLKGHYCLYGKSSFSLCSSQPHLWIQIMLLALQS----KESEALCCRDECVLQLRKLWEKTQLTGAHSFELAMTQTTVPHKKDVDSLQMYLEEVRFFDLFSYSEDKGG----------WLCFMCSNPEKAT-VVNQDGQPLIEGKLKEKQVRWKFIKRWKTRYFTLAGNQLLFRRGKSKDELDNNTIELSKVQSVKVVAKKRRDRGLPRAFEIFTDSKTYVLKAQDEKHAEEWLQCINVAVAQAKERENREATTYL-------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VS24-3", "uniprot_id": "MELT_DROME", "id": "Q9VS24-3", "name": "Protein melted", "aln": "MHELFNKVLAKRDLSRAGDLFSVPDADIVDDITEVLSEISPIISHADYVKNNNDQSVVEICVTRVLSCIRETKTAERYCAALVDLLRTCLLWNLQPSGTTKEEPPHAKIAADIISSIFLNYDKKELMKIALPVAVQFLPKGNRELSRNLASYLSLAAIDHAGLLSPHTESVMESILSGNYGLLRVLSQVYEVAPEAVTPHAPLLMPLLPQCDPQERMAVFQLYLLIV-QKSPEVLESCVPQLCGSLLDSDTSSITMQILLKLSQHSPSLLVDHFEQLRLAAKTNPGTIPLCAQIMTTAGIGSKETAQQALDFVLEHLPTQALLQQEATRLCSAYPVLFTDKVLACVRQKNAALSSQQDVGNGLANKTSGGVTIVSLNSSSPSPPLKPVPVGAPAINTTIVQPASVVSATPTPPPSSASAPIASSTPVSAATPTPQHAGYTRRVKLGDSRSTGRLHPASNTHRSVTRLNVASGSVGGLHKSMTRLSNSQINQQPGGSSNGNVVVQSGATPKTPTGLSNPPVTPVPPLSNNVVITGHNRHGIPVTSGGVTVTTSPSKVRPHSQGPSTLLNSSTVLMKYSTDALNQSVGSISIPQSAAVATLPSTQTQNAVSVHHASPALPQSASNGHAKSVMKLPVNGNSEVIVSGPTTNVAPRRSDNTSRTLLNANSVMDQRMSTFEPYQIMRDPVQQFCEKNFNSIKSYMDEVSQHLPPPTRCSIEVSNEFAERRTKKVAKLHFACQIRGPHCLYSKTCFTMRTRNPKTWIHMMFLDFQVRHFVKEKCVLSTRESGISNLKNIWQILKCE--NRSFTELVTSQFPQVKDREILVNELRHSGFLDVFEVSKTDKSNPNCNELEYQWGCFLCNHPDKAVGFLNGSNQPMIEGQLKEKKGKWRLFRRWRTRYFTLSGAHLSCKGSSGGESID--------VNQIRSVKVSRGARNIPKAFEIFTADQTLILKPKDGKNAEEWVQCLSIVVAHSQARDNPTAKTNSLPARSIGSSKPSF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:**. **.::***:******: *::* * :::.*.:*. * . ** .*:***:*****:**: :.**** : *:: ***.* :** **:* *. *:.******:** *.*: **:: :* :*:*:**:** :*.:**.**::.******* :* **: *** : *:* ** *****. ** *:.: * * .::.: : : :::* : *:.. :* * * :* .. : :*:::: .* * .: *: .: * *:* :.* .: *: .* :::. *.. . :* :: . :* . . : *. .. :::* ::: . * . . *. . :* * ..: : . :*. * :* . : : : :. * . ::: : .: . *. : : . . : . . . . : . . . : :* : . ..*:..:*:: *: :::* * :* ** . **** *:* ::* :***.*:.* : : *: **::*:* * *. :. : *: :*: : : : : .*: ** : : *.. *:*:* *: . * **:*.:*:**. .:* ..**:***:****: :*::::**:*:****:* :* : ... :. * *:.:: * .* *.:*:****** .:* ::*.:* *:****:**:.:.:*::: *:. ..* ", "identical_positions": 221, "similar_positions": 268, "identity": "21.99%" }, { "cls_id": "homologset.agr.RGD:1308218", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "F7ESE9-1", "uniprot_id": "F7ESE9_RAT", "id": "F7ESE9-1", "name": "", "aln": "----------MGTPGVSAGALFLSSASAPPRKRAAGEAGEAGVAKSKQRVLDEEEYIEVPGLQTVIQRDFFPDVEKLQAQKEYLEAEENGDLERMRQIAIKFGSALGKISREPPPP---YVTPATFETPE--VHPGSGVLGSKPRPQGRDPEDAGEAGEEE--EKEPLPSLDVFLSRYTSEDNASFQEIMEVAKEKSHARHAWLYQAEEEFEKRQKDNLELPSAEHQAIES-SQAGVETWKYKAKNSLMYYPEGVPDEE----QLFKKPRQIVHKNTRFLRDPFSQALSRSQLQQAAALNAQHKQGKVGPDGKELIPQESPRVGGFGFVATPSPAPGMNESPLMTWGEVENTPLRVEGSESPYVDRTPGPTFKILEPGRRERLGLKMANEAAAKNRAKKQEALRRVTENLAS--LTPKGLSP-AMSPALQRLVSRTASKYTDRALRASYTPSPAR--------STHLKTPAGGPQTPTSTPAPGSATRTPLTQDPASITDNLLQLP-ARRKASDFF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70279-1", "uniprot_id": "ESS2_MOUSE", "id": "O70279-1", "name": "Splicing factor ESS-2 homolog", "aln": "----------MGTPGTSAGALFLSSASAPSRKRAAGEAGEAGVARSRQRVLDEEEYIEG--LQTVIQRDFFPDVEKLQAQKEYLEAEENGDLERMRQIAIKFGSALGKISREPPPP---YVTPATFETPE--VHPGSAVLGNKPRPQGRDLDD-GEAGEEE--EKEPLPSLDVFLSQYTSEDNASFQEIMEVAKEKSHARHAWLYQAEEEFEKRQKDNLELPSAEHQAIES-SQAGVETWKYKAKNSLMYYPEGVPDEE----QLFKKPRQIVHKNTRFLRDPFSQALSRSQLQQAAALNAQHKQGKVGPDGKELIPQESPRVGGFGFVATPSPAPGVNESPLMTWGEVENTPLRVEGSESPYVDRTPGPTFKILEPGRRERLGLKMANEAAAKNRAKKQEALRRVTENLAS--LTPKGLSP-AMSPALQRLVSRTASKYTDRALRASYTPSPAR--------SSHLKTPAGGPQTPTSTPAPGSATRTPLTQDPASITDNLLQLP-ARRKASDFF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96DF8-1", "uniprot_id": "ESS2_HUMAN", "id": "Q96DF8-1", "name": "Splicing factor ESS-2 homolog", "aln": "----------METPGASASSLLLPAASRPPRKR---EAGEAGAATSKQRVLDEEEYIEG--LQTVIQRDFFPDVEKLQAQKEYLEAEENGDLERMRQIAIKFGSALGKMSREPPPP---YVTPATFETPE--VHAGTGVVGNKPRPRGRGLED-GEAGEEE--EKEPLPSLDVFLSRYTSEDNASFQEIMEVAKERSRARHAWLYQAEEEFEKRQKDNLELPSAEHQAIES-SQASVETWKYKAKNSLMYYPEGVPDEE----QLFKKPRQVVHKNTRFLRDPFSQALSRCQLQQAAALNAQHKQGKVGPDGKELIPQESPRVGGFGFVATPSPAPGVNESPMMTWGEVENTPLRVEGSETPYVDRTPGPAFKILEPGRRERLGLKMANEAAAKNRAKKQEALRRVTENLAS--LTPKGLSP-AMSPALQRLVSRTASKYTDRALRASYTPSPAR--------STHLKTPASGLQTPTSTPAPGSATRTPLTQDPASITDNLLQLP-ARRKASDFF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QAX0-1", "uniprot_id": "F1QAX0_DANRE", "id": "F1QAX0-1", "name": "", "aln": "----------MAESREKAVCLRSDVTTVAVRNP----VEES--KKPKRKILDEEQYIES--LEKIIQRDFFPDVSKLQAQKDYLEAEENGDLERMREIAIKYGSAMAKYTPRTYVP---HVTPSTFETPD--GRSAS---PSSSQSKSRAAREDGKDGEKA--SEKDLPSLDRFLSKNTSEDNASFEQIMELAEDKDKLRHAWLYEAENEYKERHEQNLALPSSEKQALEC-TKAGLETWQYKAKNSLMYYPEGEKDD-----TLFKKPREVLYKNTRFEDDPFCKALNKSQIQQAAALNAQFKQGKVGPDGKELLPHESPKVNGYGYEGAPSPAPGVAESPLMTWGEIESTPFRLEGSDTPLVERSHGPSFKIPEPGRRERLGLKMANEAAAKNRAKKQEALRKVTENLAS--LTPKGLSPAALSPALQRLVNRSSSKYTDKALRASYTPSPAHR-------SLGAKTPSGGLTTLTPTPTK---TRTPASQDPASITDNLLQLP-KRRKAQDYF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O44424-1", "uniprot_id": "ESS2_DROME", "id": "O44424-1", "name": "Splicing factor ESS-2 homolog", "aln": "MSATTRTPATPGTPGTPGSLAMEVARVQNSALAEFKKPTAMVRHKNKPKILTEEKYIEE--MSKIIQRDFFPDLERLRAQNDYLDAESRRDFVQMAEIRERYSLGRISGTGRSTSRRNNAMSPATFETPVSQAKCSNTPLPNSRATDTPFSTDGSEKSDAEGRDTTAKLSLDAFLQKYTSEDNQSFQEIIETAEAKLRQKYAVLYNHEKLSAEQLQRALMLPSIETQFEEPDPLRKIETWNYTNMNSIMYVPDGVEYTEEERVQLAERKQSIQHNATRLPDEAKHREMDTKKLNDEVPQNGAGG------------ATATPKVRGFDLLRSPSPRPGEAFSPIMTWGEIDGTPFRLDGGDTPLRP-TQGPSFRINENSRRENIAIALAERVSERMRNQKQMALDTARRNIGSPLIRTNMERLASMSPAAQLLATGKLGIRGTPRLRHTPSPMSGRKRKVTPGVVRSTNTPILGEPKPKQQAKISTPAKNVTIDTGSTLTDDLLKIPTKRRTAADFF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : ::* **:*** :..:********:.:*:**::**:**.. *: :* :* ::. . . : .. ::*:***** : .. .. . : .: .: . *** **.: ***** **::*:* *: : : ::* **: *: :: : * *** * * * . :***:*. **:** *:* * :: :.: :: **: :. : :. :::: .. *. . :*:* *:. :*** ** **:*****::.**:*::*.::* : **:*:* * .***.:.: :*:..: : * :** ** . .*:.* : .: ::*** * *.. . . ** : :* ..: :** * . . . ::. : :::**:**::* **.* *:*", "identical_positions": 127, "similar_positions": 151, "identity": "24.61%" }, { "cls_id": "homologset.agr.RGD:1308221", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q3UYK3-1", "uniprot_id": "TBCD9_MOUSE", "id": "Q3UYK3-1", "name": "TBC1 domain family member 9", "aln": "MWVNPEEVLLANALWITERANPYFILQRRKGHGGDGGGGGGLAGLLVGTLDVVLDSSARVAPYRILYQTPDSLVYWTIACGGSRKEVTEHWEWLEQNLLQTLSIFENENDVTTFVRGKIQGIIAEYNKINDVKEDEDTEKFKEAIVKFHRLFGMPEEEKLVNYYSCSYWKGRVPRQGWMYLSINHLCFSSFLMGREAKLVIRWVDITQLEKNATLLLPDMIKVSTRSSEHFFSVFLNINETFKLMEQLANIAMRQLLDNEG---FEQDRSLPKLKKKSPKKVSALKRDLDARAKSERYRALFRLPKDEKLDGHTDCTLWTPFNKMHILGQMFVSTNYICFTSKEENLCSLIIPLREVTIVEKADSCS-VLPSPLSISTRNRMTFLFANLKDRDFLVQRISDFLQQTTSRIYSDKEFSGSCNSSDDEVYSRPSSLVSSSPQRSTSSDADGERPFNLNGNSVPTATQTLMTMYRRRSPEEFNPKLAKEFLKEQAWKIHFAEYGQGICMYRTEKTRELVLKGIPESMRGELWLLLSGAINEKATHPGYYEGLVEKSMGKYN-LATEEIERDLHRSLPEHPAFQNEMGIAALRRVLTAYAFRNPNIGYCQAMNIVTSVLLLYAKEEEAFWLLVALCERMLPDYYNTRVVGALVDQGVFEELARDYVPQLYDCMQDLGVIS-TISLSWFLTLFLSVMPFESAVVVVDCFFYEGIKVIFQLALAVLDANVDKLLNCKDDGEAMTVLGRYLDSVTNKDSTLPPIPHLHSLLSDDVGPYPAVDIFRLIGTSYEKFGT-IRADLIEQMRFKQRLKVIQTLEDTTKRNVVRTIVTETSFTIDELEELYALFKAEHLTSCYWG-------------------GSSNALDRHDPSLPYLEQYRIDFEQFKGMFVLLFPWACGTHSDVLASRLFQLLDENGDSLINFREFVSGLSAACHGDLTEKLKLLYKMHVLPEPS------------CDQDEPDSAFEATQYFFEDITPECTHVVGLDSRGKQSADDGFVTVSLKQDRGKRANSQENRNYLKLWTAENKSKSKTAKDLPKLNQGQFIELCKTMYNMFSEDPNEQE-------LYHATAAVTSLLLEIGEVGKFFITQPAK---EDAVPG--PPCGQAIPGMLFPKKGSSQSYVVESTEPLTASLAVDSEEHSLG------------------------------------GQMEDIKLEDSSPRDNGACSSMLISDDDTKDDSSMSSYSVLSAGSHEEDK--------------------LHCEDIGEDTVLVRSSQGRATLPRSSSLDRDWAITFEQFLASLLTEPALVRYFDKPVCMMARVTSAKNIRMMGKPLTSASDYEISALSG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZXE3-1", "uniprot_id": "D3ZXE3_RAT", "id": "D3ZXE3-1", "name": "TBC1 domain family member 9", "aln": "MWVNPEEVLLANALWITERANPYFILQRRKGHGGDGGGGGGLAGLLVGTLDVVLDSSARVAPYRILYQTPDSLVYWTIACGGSRKEVTEHWEWLEQNLLQTLSIFENENDVTTFVRGKIQGIIAEYNKINDVKEDEDTEKFKEAIVKFHRLFGMPEEEKLVNYYSCSYWKGKVPRQGWMYLSINHLCFSSFLMGREAKLVIRWVDITQLEKNATLLLPDMIKVSTRSSEHFFSVFLNINETFKLMEQLANIAMRQLLDNEG---FEQDRSLPKLKKKSPKKVSALKRDLDARAKSERYRALFRLPKDEKLDGHTDCTLWTPFNKMHILGQMFVSTNYICFTSKEENLCSLIIPLREVTIVEKADSCS-VLPSPLSISTRNRMTFLFANLKDRDFLVQRISDFLQQTTSRIYS--EFSGSCNSSDDEVYSRPSSLVSSSPQRSTSSDADGERPFNLNGNSVPTATQTLMTMYRRRSPEEFNPKLAKEFLKEQAWKIHFAEYGQGICMYRTEKTRELVLKGIPERMRGELWLLLSGAINEKATHPGYYEDLVEKSMGKYN-LATEEIERDLHRSLPEHPAFQNEMGIAALRRVLTAYAFRNPNIGYCQAMNIVTSVLLLYAKEEEAFWLLVALCERMLPDYYNTRVVGALVDQGVFEELARDYVPQLYDCMQDLGVIS-TISLSWFLTLFLSVMPFESAVVVVDCFFYEGIKVIFQLALAVLDANVDKLLGCKDDGEAMTVLGRYLDSVTNKDSTLPPIPHLHSLLSDDVGPYPAVDIFRLIGTSYEKFGT-IRADLIEQMRFKQRLKVIQTLEDTTKRNVVRTIVTETSFTIDELEELYALFKAEHLTSCYWG-------------------GSSNAPDRHDPSLPYLEQYRIDFEQFKGMFVLLFPWACGTHSDVLASRLFQLLDENGDSLINFREFVSGLSAACHGDLTEKLKLLYKMHVLPEPS------------CDQDEPDSAFEATQYFFEDITPECTHVVGLDSRGKQSADEGFVTVSLKQDRGKRANSQENRHYLKLWTAENKSKSKNAKDLPKLNQGQFIELCKTMYNMFSEDPNEQE-------LYHATAAVTSLLLEIGEVGKFFITQPAK---EDAVPG--PPCSQAIPGMLFPKKGSSQSYVVESTDPLPASLAGDREEHSLG------------------------------------GQMEDIKLEDSSPRDNGACSSMLISDDDTKDDSSMSSYSVLSAGSHEEDK--------------------LHCEDIGEDTVLVRSSQGRAALPRSSSLDRDWAITFEQFLASLLTEPALVRYFDKPVCMMTRVTSAKNIRMMGKPLTSASDYDISALSG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZT07-1", "uniprot_id": "TBCD9_HUMAN", "id": "Q6ZT07-1", "name": "TBC1 domain family member 9", "aln": "MWVNPEEVLLANALWITERANPYFILQRRKGHAGDGGGGGGLAGLLVGTLDVVLDSSARVAPYRILYQTPDSLVYWTIACGGSRKEITEHWEWLEQNLLQTLSIFENENDITTFVRGKIQGIIAEYNKINDVKEDDDTEKFKEAIVKFHRLFGMPEEEKLVNYYSCSYWKGKVPRQGWMYLSINHLCFYSFLMGREAKLVIRWVDITQLEKNATLLLPDVIKVSTRSSEHFFSVFLNINETFKLMEQLANIAMRQLLDNEG---FEQDRSLPKLKRKSPKKVSALKRDLDARAKSERYRALFRLPKDEKLDGHTDCTLWTPFNKMHILGQMFVSTNYICFTSKEENLCSLIIPLREVTIVEKADSSS-VLPSPLSISTRNRMTFLFANLKDRDFLVQRISDFLQQTTSKIYSDKEFAGSYNSSDDEVYSRPSSLVSSSPQRSTSSDADGERQFNLNGNSVPTATQTLMTMYRRRSPEEFNPKLAKEFLKEQAWKIHFAEYGQGICMYRTEKTRELVLKGIPESMRGELWLLLSGAINEKATHPGYYEDLVEKSMGKYN-LATEEIERDLHRSLPEHPAFQNEMGIAALRRVLTAYAFRNPNIGYCQAMNIVTSVLLLYAKEEEAFWLLVALCERMLPDYYNTRVVGALVDQGVFEELARDYVPQLYDCMQDLGVIS-TISLSWFLTLFLSVMPFESAVVVVDCFFYEGIKVIFQLALAVLDANVDKLLNCKDDGEAMTVLGRYLDSVTNKDSTLPPIPHLHSLLSDDVEPYPEVDIFRLIRTSYEKFGT-IRADLIEQMRFKQRLKVIQTLEDTTKRNVVRTIVTETSFTIDELEELYALFKAEHLTSCYWG-------------------GSSNALDRHDPSLPYLEQYRIDFEQFKGMFALLFPWACGTHSDVLASRLFQLLDENGDSLINFREFVSGLSAACHGDLTEKLKLLYKMHVLPEPS------------SDQDEPDSAFEATQYFFEDITPECTHVVGLDSRSKQGADDGFVTVSLKPDKGKRANSQENRNYLRLWTPENKSKSKNAKDLPKLNQGQFIELCKTMYNMFSEDPNEQE-------LYHATAAVTSLLLEIGEVGKLFVAQPAK---EGGSGGSGPSCHQGIPGVLFPKKGPGQPYVVESVEPLPASLAPDSEEHSLG------------------------------------GQMEDIKLEDSSPRDNGACSSMLISDDDTKDDSSMSSYSVLSAGSHEEDK--------------------LHCEDIGEDTVLVRSGQGTAALPRSTSLDRDWAITFEQFLASLLTEPALVKYFDKPVCMMARITSAKNIRMMGKPLTSASDYEISAMSG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VP46-1", "uniprot_id": "Q9VP46_DROME", "id": "Q9VP46-1", "name": "", "aln": "MWIQPKELLLPSAFWIAEMHSRYFVLQKRRGHGESRGFG----SMLVGTYDSVMN--TKPAPYRILHQTPSSEVSYEIAIGITQDEIVKDWEWLKANLFKVLDEMENEDEVTNFTICKIQSLYTQNNQD----DTGESADFKVMKSKFRQIFKMPEEERLVISYSATYVKNKIPRQGQLYISLNHVCFYSYMLGQEIKRIIRFAELEDISRNANTIYLKTTNNMTYN----FTMLFNASDAHLLIEQLNKMAIQQLIHDPDSPVVDHDTSNFSRLGSKTSKKPVLLRDLTARQKSEEFRIYFRLPQSEIIDGKIKANIWTPYSKRFNSGFIYLSPNFFCFRSDVKDLVSVVIPMKTIKSVEKKDDGQQRFENQIVIITSENVPFMFAHIVDRAVLISKITDLLARVHVPLSRE-------RAKYDISWSKQTALMNTFKTQFSAEIIQ------------------------------------KQEEKMVRWEAHFRDFGRGIGMFRTTDVINLIVEGIPDKLRQEIWLIFSGAIHDKEMNPGLYEDLVEKAACIKNCFAHDEIDRDLPRSLPEHPAFQSTDGIGALRRVLQAYALRNPQVGYCQAMNIVSSVFLLFCDEENAFWMLASLCENLLPDYYKDKVVGAQIDQGVLNELVETHLPDLHGHLEQLGVIK-MISISWFLTIFMSVISYESSLHILDCFFYEGAKIIFMISLQIIEWNRDKLLICQDDGEAMLVLQNYLEGVYNPEYQVPPTTDKRKMER----KVQTQTVQTLIHEAYTKFGEDITQQRIEELRNKHRRLTMRQFDIDNEKTIVKAYVQNPYFNRSELHMLLTIIREEKHALKSLQQQQQKVQCPLSETPQLVPQSTSRPIQDAGASGGRYEAYSVSYEVFHTLFTELTPWRKCVSVDIG-EKLFRLTDKKGTGVLDFGQLINALGLVCSNKNMEKLKLLYVLHLPPLLSKAEIERSRRPRPRTKDDAEEAFEAEDFFDNDASESMEALP--SPSDHNFDADDFALISATQHLHNLAGISGN-TFMDLSRTPNLSVNSNTSSLAHRSSTFYVDLPGFQGTATSTDAGRDEDELQRQLRQQGRYESIDTFSDISDLGAARITPPEAGVGADVVAG--AASSAAADHMLLNVETISNFSQISDLVAATRLERVDSNATDLRSLGSLGYLLDQPDEGASNSQHSIPHMRKENFQLLWRSIIEIMGLVQDEEMQRAYENLLELGNSNIKKEPSLESFTQLNMGGDEQPDSNGNPTTPAPEPIGTTRLFVALEEELRQASGKSRTTTTSSGDSSSTNISESWHISITQFIATVLTVNSIVRGFQTPIQISEQIEQLQKKRRK----CLSTNY-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53258-1", "uniprot_id": "GYP2_YEAST", "id": "P53258-1", "name": "GTPase-activating protein GYP2", "aln": "--------------------MSFFDSLRQKAP------------FLDKLADSFTPTLTRDEKFRLKYKLPAN-----------------------------ENILEDTNAEVSFATSIKD-------------GKGHSDRVNNKGRKTAYVY-----------------------SGRLFLTPHFLVFRDAFDHSSCVLILNISTIKRVERSP-----------------------------------------------------SESYEFALLVTLYTGAKVLIQFIGIRYRSEQFCDKLKLNLKENIP-----------NAKTLPAFLETSYSEFLIAKNILGKKDITVPRAGLGQHFKYPGNP------------------------------------------------------------------------------------------------------------------TMVKEKAKLRLWFDYFRENGRNLAVVQTPMFRKLIRIGVPNRMRGEIWELCSGAMYMRYANSGEYERILNENAGKTS-QAIDEIEKDLKRSLPEYSAYQTEEGIQRLRNVLTAYSWKNPDVGYCQAMNIVVAGFLIFMSEEQAFWCLCNLCDIYVPGYYSKTMYGTLLDQRVFESFVEDRMPVLWEYILQHDIQLSVVSLPWFLSLFFTSMPLEYAVRIMDIFFMNGSITLFQVALAVLKINADDILQADDDGMFIAIIKHYFQTLGQSAHPDSSDIKYR----------QITKFQELLVTAFKEFSV-ISEEMAMHARHKYEKGIFQNIETFMKRTQLRHMPKTFNLSSDDLSNIYDMFYQSIETYKISMG-----------------------TGSSNMGFEVFIQFLSKFCDSCRPCEKDKDPAFRKQKRNFLQRLFDNWDSAHIGELTLNDVVTGLDKLVTVDLLQAINYFFSLYDTDGDGE------LHREEVLQLSEGLLLLTEPWKSGRYVDLLTKKRIEDDIAENIIKESGGEIATMNQIELPTGVTIDEEKYKVEQAERYLKAASNFLQRSFEYAKAVDLAEEVNLIDLSDDEGEE----KRTVKQKQLESIKANAALDPTHPKVIDLPTFR----MIILADETYELFFSNTLRSSVHVDEHVNIDNKNKVLRSMFDGILADGKR------------------------------------------VAEQVRRRVDSVATRSSIASVESTPTAAASSITTKEEKYDDLDD--------------------FTSEHQPENEELLQSSWFEIDDANETSTKAIQERSFEPLSANSSEEKSNLIEFEA----------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* :::. :* * . :: :*: :: * . . :*: : ..*. : .: .: * :: .* :::: :.: * . : . ::. : :.:.. : . . .* : : * :**.: ::* .* : . . : * . : : .. . .: :* : * . *: * * :* : *:.: : :* :*: *:*: :* *:* : ***: : :.* ** :::: . * :**::** *****:.*:*. ** **.** **: :**::********* : :*:: .**:*** * **: :*.**. : *: :** *::.:.. :* * : : .: :*:.***::*:: :. * :: ::* ** :* :* ::* ::. * *.:* ..*** : :: .*:: : : .. . : . *: :: :*. * : . * * . :: :: ::. :: :. .:* : :: . : . . : .: .:** *. . : : :.:..*. . : :: :: :: . : . : : : . .: :. :: . :. : : . . . . ::* * :* : . :. : * . * .: :.. . . : . . :.. : . .: .* : . .: . *. : :: . .:. . :: : *. : : *: ", "identical_positions": 124, "similar_positions": 293, "identity": "9.05%" }, { "cls_id": "homologset.agr.RGD:1308222", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZRH6-1", "uniprot_id": "D3ZRH6_RAT", "id": "D3ZRH6-1", "name": "Ligand of Numb protein X 2", "aln": "MGTTSDEMVPVQQASSASSLDPLCFECGQQHWARENHLYNYQGEVDDDLVCHICLQPLLQPLDTPCGHTFCHKCLRNFLQEKDFCPLDRKRLHFKLCKKSSILVHKLLDKLLVLCPFSSVCQDVMQRCDLEAHLKNRCLGASHRRVDLERRKTSQAHTQIEG-ETGSTVIDPPGPSPPETDCLGT--VPGERNSTPAPLPVWTEDPGLDNPAFEESAAADSVQ----------QPLS------------------------------------LPEGEITTIEIHRTNPYIQLGISIVGGNETPLINIVIQEVYRDGAIARDGRLLAGDQILQVNNCDISNVSHNYARAVLSQPCSTLHLTVLRERRFGSRANNHADGSAPRDEVFQVLLHKRDSAEQLGIKLVRRTDEPGVFILDLLEGGLAAQDGRLSSNDRVLAINGHDLKQGTPELAAHIIQASGERVNLTIARPGKPQPSNGSREAGAHSS---NHAQPP------------SHSRPSSHKDLTRCVTCQEKHITVKKEPHESLGMTVAGGRGSKSGELPIFVTSVPPHGCLARDGRIKRGDVLLNINGIDLTNLSHSEAVAMLKASAASPAVILKALEVQIAEEAAQATEEQPGAFSENEYDASWSPSWVMWLGLPSALHSCHDIVLRRSYLGSWGFSIVGGYEENHSNQPFFIKTIVLGTPAYYDGRLKCGDMIVAVNGLSTVGMSHSALVPMLKEQRNKVTLTVVCWPGSLV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91XL2-1", "uniprot_id": "LNX2_MOUSE", "id": "Q91XL2-1", "name": "Ligand of Numb protein X 2", "aln": "MGTTSDEMVPVEQASSTSSLDPLCFECGQQHWARENHLYNYQGEVDDDLVCHICLQPLLQPLDTPCGHTFCHKCLRNFLQEKDFCPLDRKRLHFKLCKKSSILVHKLLDKLLVLCPFSPVCQDVMQRCDLEAHLKNRCPGASHRRVDLERRKTSQTQTQIEG-ETGSTVIDPPGTLPPETDCSGT--VPGERNLTPASLPVWTEEPGLDNPAFEESAAADSVQ----------QPLS------------------------------------LPEGEITTIEIHRSNPYIQLGISIVGGNETPLINIVIQEVYRDGVIARDGRLLAGDQILQVNNYDISNVSHNHARAVLSQPCSTLQLTVLRERRFGSRANSHADGSAPRDEVFQVLLHKRDSTEQLGIKLVRRTDEPGVFILDLLEGGLAAQDGRLNSNDRVLAINGHDLKHGTPELAAQIIQASGERVNLTIARPGKPQPSNGSREAGAHSSS--NHAQPP------------SHSRPGSHKDLTRCVTCQEKHITVKKEPHESLGMTVAGGRGSKSGELPIFVTSVPPHGCLARDGRIKRGDVLLNINGIDLTNLSHSEAVAMLKASAASPAVILKALEVQIAEEAAQATEEQPSAFSENEYDASWSPSWVMWLGLPSALHSCHDIVLRRSYLGSWGFSIVGGYEENHTNQPFFIKTIVLGTPAYYDGRLKCGDMIVAVNGLSTVGMSHSALVPMLKEQRNKVTLTVICWPGSLV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N448-1", "uniprot_id": "LNX2_HUMAN", "id": "Q8N448-1", "name": "Ligand of Numb protein X 2", "aln": "MGTTSDEMVSVEQTSS-SSLNPLCFECGQQHWTRENHLYNYQNEVDDDLVCHICLQPLLQPLDTPCGHTFCYKCLRNFLQEKDFCPLDRKRLHFKLCKKSSILVHKLLDKLLVLCPFSSVCKDVMQRCDLEAHLKNRCPGASHRRVALERRKTSRTQAEIEN-ENGPTLLDPAGTLSPEADCLGTGAVPVERHLTSASLSTWSEEPGLDNPAFEESAGADTTQ----------QPLS------------------------------------LPEGEITTIEIHRSNPYIQLGISIVGGNETPLINIVIQEVYRDGVIARDGRLLAGDQILQVNNYNISNVSHNYARAVLSQPCNTLHLTVLRERRFGNRAHNHSDSNSPREEIFQVALHKRDSGEQLGIKLVRRTDEPGVFILDLLEGGLAAQDGRLSSNDRVLAINGHDLKYGTPELAAQIIQASGERVNLTIARPGKPQPGNTIREAGNHSSSSQHHTPPP------------YYSRPSSHKDLTQCVTCQEKHITVKKEPHESLGMTVAGGRGSKSGELPIFVTSVPPHGCLARDGRIKRGDVLLNINGIDLTNLSHSEAVAMLKASAASPAVALKALEVQIVEEATQNAEEQPSTFSENEYDASWSPSWVMWLGLPSTLHSCHDIVLRRSYLGSWGFSIVGGYEENHTNQPFFIKTIVLGTPAYYDGRLKCGDMIVAVNGLSTVGMSHSALVPMLKEQRNKVTLTVICWPGSLV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R5N4-1", "uniprot_id": "F1R5N4_DANRE", "id": "F1R5N4-1", "name": "", "aln": "MGSLGEGVDP--GMVSEALLEALCSECGQIHRTWENHLYNYRLEVDDDLVCHICLQPLVQPLDTPCGHTFCARCLRSFLQERDFCPLDRAHLQLQVCRRSSILVHKLLDKLSVTCPLTPSCSLSMPRCDLEAHLKHRCPGTQSQRTKLER-------TQMEGSEDRVTATNPP--KSPQTEIKEDTPSPPAGSNACNNVPTWTEEPGIDNPAFEESTEEDSVHGLECALPRVKRPLSNPCIHLLRTGSSASSGWDFVETLPLSAEEGCVKLPSLPEGEITTIEVHRTNPYSEMGISIVGGNETPLINVVIQEVYRDGVIARDGRLLAGDQILQVNNVDISNVPHNFARSTLARPCATLQLTVLRERRCSARPPAATASPKGSPASIRITLHKRESSEQLGIKLVRRTDEAGVFILDLLEGGLAAKDGRLCSNDRVLAVNEHDLRHGTPELAAQIIQASGERVNLLISRSSKQTMAVHTGSTLTRDIWSHDHIPPLPSTATPSPVPSLHLARSSTQRDLSQCVNCKEKHITVKKEPHESLGMTVAGGRGSKSGELPIFVTSVQPHGCLSRDGRIKRGDVLLSINGQDLTYLSHSEAVGTLKSSATSCSVQLKALEVTMVEEPGLDEELLPP--HENDYDASWSPSWVLWLGLPSYLHSSHEIVLRRSHPGSWGFSIVGGYEENHSNQAFFIKTIVLGTPAYYDGRLKCGDMIVAVNGLSTAGMSHSALVPMLKEQRSRVALTVVSWPGSLI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: .: : . * : *:.** **** * : *******: ***************:************ :***.****:******* :*::::*::************ * **::. *. * *********:** *:. :*. *** :::*. * * :*. .*::: * : :..*:*:**:********: *:.: :*** **********:**:*** ::**************:*********.****************** :****.**.**:.*::** **:******** . *. : . ::: ****:* *************.**************:**** *******:* ***: *******:*********** *:*..* . .: :. .* * :*..:::**::**.*:************************************ *****:************.*** *** *******. **:**:* :* ****** :.**. * * **:**********:****** ***.*:******: ***************:**.********************************.***************.:*:***:.*****:", "identical_positions": 453, "similar_positions": 121, "identity": "60.4%" }, { "cls_id": "homologset.agr.RGD:1308223", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q499V3-1", "uniprot_id": "RAD9B_RAT", "id": "Q499V3-1", "name": "Cell cycle checkpoint control protein RAD9B", "aln": "-----MTGGQVKVFGKAIQTLSRVSDELWLDPSEKGLALRSVNSCHSTYGYVLFSSVFFQHYQWSPSATITDS--DIPLNLNCKLAIKSILPIFRCLNYLERSIEKCTMVARSDRCRVVIQFFGRHGIKRTHNVYFQDCQPLKILFEKSLCANILMIKPRLLAEAIALLTSNQEEVTFSVTPENFCLKSSSGESLDLTSSVYSEMSFGPEEFDFFQVGLDTEITFCFKELKGILTFSEVMHAPIAIYFDFPGKPVVLSVEDMLLEASFILATLLDYPSRTSSPQSLRLSQAR-RSDPTLSGAQEGKSRVSQTPESISR----AAPKRLFPKDPPDSSSAAETRRASASQ---DDISEVPES---------------------------VVSDMEEGQSPSPLRKFSCMFFGAVSCEQQEHANHPLGSLAVASDSEQDASG---------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6WBX7-1", "uniprot_id": "RAD9B_MOUSE", "id": "Q6WBX7-1", "name": "Cell cycle checkpoint control protein RAD9B", "aln": "MLKCGMTGGQVKVFGKAVQTLSRVSDELWLDPSEKGLALRSVNSCHSTYGYVLFSSMFFQHYQWSPFATMSDT--DLPLNLNCKLAIKSVLPIFRCLNYLERSVEKCTVVARADKCRVVIQFFGKHGIKRTHNVYFQDSQPLKIIFEKSLCANILMIKPRLLTEAIALLTSNQEEVTFSVTPGNFCLKSLSGELLDLTSSVYSEMSFGPEEFDFFQVGLDTEITFCFKELKGILTFSEVMHAPLAIYFDFPGKPVVLSVEDMLLEANFILATLVDYPSRTSSPQLLPLSQAR-RSHPIQSSAPEDKSRVSQTPESISR----AAPKRLFPKDSPDSSSAAETKRASAGQ---DDIFEVPES---------------------------VVSDMEEERSPSHLRKFSCMFFGAVSCEQQEYAGHPLDSLAVASDSEEDVSG---------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6WBX8-5", "uniprot_id": "RAD9B_HUMAN", "id": "Q6WBX8-5", "name": "Cell cycle checkpoint control protein RAD9B", "aln": "MLKCVMSGSQVKVFGKAVQALSRISDEFWLDPSKKGLALRCVNSSRSAYGCVLFSPVFFQHYQWSALVKMSENELDTTLHLKCKLGMKSILPIFRCLNSLERNIEKCRIFTRSDKCKVVIQFFYRHGIKRTHNICFQESQPLQVIFDKNVCTNTLMIQPRLLADAIVLFTSSQEEVTLAVTPLNFCLKSSNEESMDLSNAVHSEMFVGSDEFDFFQIGMDTEITFCFKELKGILTFSEATHAPISIYFDFPGKPLALSIDDMLVEANFILATLADEQSRASSPQSLCLSQKRKRSDLIEKKAG--KNVTGQALECISKK---AAPRRLYPKETLTNISALENCGSPAMKRVDGDVSEVSES---------------------------SVSNTEEVPGSLCLRKFSCMFFGAVSSDQQEHFNHPFDSLARASDSEEDMNNVC--CRKEFNGSDAKYFCII-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O96533-1", "uniprot_id": "RAD9_DROME", "id": "O96533-1", "name": "Cell cycle checkpoint control protein Rad9", "aln": "-MKYTLEGSNARVIAKAVQSLSKVGKEMFIEIDQQSLQMRAINATQSAVGSISFKRSMFEVYDMPPHS-----------DFYCKISMKGCLAVFRNMN----EVEYCELNLLDNQTNLQVNLRCKLETTKEATISIIDDQNINTNINTDQMPNIIRGDHKLLTDISNNFNSSEEELTLEANSGSVVAKNYIEGARVNDKFMRTQLKLKPSEFEQYQVTKETVITFCIKEFRAFLLFAECLNASLTLEFDEAGMPFLLKIKKHGEIECLLIMSTLS-PDDISFSEDYCQKDLTVQDEDVRAAAAKRKSSVSKPNVTNKRKGSSSEPAAVQPKRRVEETQLESSLDNPLFQFRDSEAPSVQHPRILAEVDTVVLIEDEAEQEALMLAAADAALEASMAPAPEPPNSTEVCFINTDDSQQPKPAKSSSDEDETIPQSPERPNKVLGVLLGLLQGCVSRLKTMLRLDEHLISGYELL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *.:.:*:.**:*:**::..*:::: .::.* :*.:*: :*: * : *. :*: *: .. .: **:.:*. *.:** :* .:* * : :: .: ::: : .: .: : : * :: ::.. .* : . :**:: :.*.:**:*: ... .. *. . : ::: . ..**: :*: :* ****:**::.:* *:* :*.::: ** .* *. *.:.. ::: : . . * .: .: :.. * *. ..:. .: : * : ** . . .. . : .: .* .. . : . .. .. . *:.: ..:* : . .. .:* : . ", "identical_positions": 63, "similar_positions": 168, "identity": "13.32%" }, { "cls_id": "homologset.agr.RGD:1308225", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JWQ0-1", "uniprot_id": "A0A0G2JWQ0_RAT", "id": "A0A0G2JWQ0-1", "name": "General transcription factor IIH subunit 1", "aln": "---------------------------------------------------MATSSEEVLLIVKKVRQKKQ-------------DGALYLMAERIAWAPEGKDRFTISHMYADIKCQKISPEGKAKIQLQLVLHAGDTTNFHFSN---ESTAVKERDAVKDLLQQLLPKFKRKANKELEEKNRMLQEDPVLFQLYKDLVVSQVISAEEFWANRLNVNATESS-TSSHKQDVGISAAFLADVRPQTDGCNGLRYNLTSDIIESIFRTYPAVKMKYAETVPHNMTEKEFWTRFFQSHYFHRDR----LNTGSKDLFAECAKIDEKGLKTMVSLGVKNPMLDLTALE----DKPLDEGYG---ISSVPSTSNSKSIKENSNAAIIKRFNHHSAMVLAAGLRKQQAQNGQNGEPSSVDG------------------------NSGDTDCFQPAVKRAKLQESIEYEDLG----------NNNSVKTIALNLKKSDRYYHGPTPIQSLQYATSQDIIN----SFQSIRQEMEAYTPKLT-QVLSSSAASSTITALSPGGALMQGGTQQ---AVNQMVPNDIQSELKHLYVAVGELLRHFWSCFPVNTPFLEEKVVKMKSNLERFQVTKLCPFQEKIRRQY--LSTNLVTHIEEMLQTAYNKLHSWQSRRLMKKT---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DBA9-1", "uniprot_id": "TF2H1_MOUSE", "id": "Q9DBA9-1", "name": "General transcription factor IIH subunit 1", "aln": "---------------------------------------------------MATSSEEVLLIVKKVRQKKQ-------------DGALYLMAERIAWAPEGKDRFTISHMYADIKCQKISPEGKAKIQLQLVLHAGDTTNFHFSN---ESTAVKERDAVKDLLQQLLPKFKRKANKELEEKNRMLQEDPVLFQLYKDLVVSQVISAEEFWANRLNVNATDSS-TSSHKQDVGISAAFLADVRPQTDGCNGLRYNLTSDIIESIFRTYPAVKMKYAETVPHNMTEKEFWTRFFQSHYFHRDR----LNTGSKDLFAECAKIDEKGLKTMVSLGVKNPMLDLTSLE----DKPLDEGYS---ISSVPSTSNSKSIKENSNAAIIKRFNHHSAMVLAAGLRKQQAQNGQNGEPSSVDG------------------------NSGDTDCFQPAVKRAKLQESIEYEDLG----------NNNSVKTIALNLKKSDRYYHGPTPIQSLQYATSQDIIN----SFQSIRQEMEAYTPKLT-QVLSSSAASSTITALSPGGALMQGGTQQ---AVNQMVPNDIQSELKHLYVAVGELLRHFWSCFPVNTPFLEEKVVKMKSNLERFQVTKLCPFQEKIRRQY--LSTNLVSHIEEMLQTAYNKLHTWQSRRLMKKT---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P32780-1", "uniprot_id": "TF2H1_HUMAN", "id": "P32780-1", "name": "General transcription factor IIH subunit 1", "aln": "---------------------------------------------------MATSSEEVLLIVKKVRQKKQ-------------DGALYLMAERIAWAPEGKDRFTISHMYADIKCQKISPEGKAKIQLQLVLHAGDTTNFHFSN---ESTAVKERDAVKDLLQQLLPKFKRKANKELEEKNRMLQEDPVLFQLYKDLVVSQVISAEEFWANRLNVNATDSSSTSNHKQDVGISAAFLADVRPQTDGCNGLRYNLTSDIIESIFRTYPAVKMKYAENVPHNMTEKEFWTRFFQSHYFHRDR----LNTGSKDLFAECAKIDEKGLKTMVSLGVKNPLLDLTALE----DKPLDEGYG---ISSVPSASNSKSIKENSNAAIIKRFNHHSAMVLAAGLRKQEAQNEQTSEPSNMDG------------------------NSGDADCFQPAVKRAKLQESIEYEDLG----------KNNSVKTIALNLKKSDRYYHGPTPIQSLQYATSQDIIN----SFQSIRQEMEAYTPKLT-QVLSSSAASSTITALSPGGALMQGGTQQ---AINQMVPNDIQSELKHLYVAVGELLRHFWSCFPVNTPFLEEKVVKMKSNLERFQVTKLCPFQEKIRRQY--LSTNLVSHIEEMLQTAYNKLHTWQSRRLMKKT---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q960E8-1", "uniprot_id": "TF2H1_DROME", "id": "Q960E8-1", "name": "General transcription factor IIH subunit 1", "aln": "---------------------------------------------------MTTSSEDVLLQMGEVRYKKG-------------DGTLYVMNERVAWMAEHRDTVTVSHRYADIKTQKISPEGKPKVQLQVVLHDGNTSTFHFVNRQGQAAMLADRDKVKELLQQLLPNFKRKVDKDLEDKNRILVENPNLLQLYKDLVITKVLTSDEFWATHAKDHALKKM---GRSQEIGVSGAFLADIKPQTDGCNGLKYNLTSDVIHCIFKTYPAVKRKHFENVPAKMSEAEFWTKFFQSHYFHRDR----LTAGTKDIFTECGKIDDQALKAAVQQGAGDPLLDLKKFE----DVPLEEGFGS--VAGDRNVVNSGNIVHQN---MIKRFNQHSIMVLKTCANVTSAPSTMTNGTNNANGPVSQSAYTNGMNGKGQATATATKSSSDQVDKDEPQSKKQRLMEKIHYVDLGDPILEGDDSANGEKAKSKHFELSKVERYLNG--PVQNSMYDNHNDPMSLEEVQYKLVRNSESWLNRNVQRTFICSKAAVNALGELSPGGSMMRGFQEQ---SAGQLVPNDFQRELRHLYLSLSELLKHFWSCFPPTSEELETKLQRMHETLQRFKMAKLVPFENRAMHELSPLRSSLTQHLNQLLRTANSKFATWKERKLRNTR---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32776-1", "uniprot_id": "TFB1_YEAST", "id": "P32776-1", "name": "General transcription and DNA repair factor IIH subunit TFB1", "aln": "MSHSGAAIFEKVSGIIAINEDVSPAELTWRSTDGDKVHTVVLSTIDKLQATPASSEKMMLRLIGKVDESKKRKDNEGNEVVPKPQRHMFSFNNRTVMDNIKMTLQQIISRYKDADIYEEKRRREESAQHTETPMSSSSVTAGTPTPHLDTPQLNNGAPLINTAKLDDSLSKEKLLTNLKLQQSLLKGNKVLMKVFQETVINAGLPPSEFWSTRIPLLRAFAL---STSQKVGP-YNVLSTIKPVASSENKVNVNLSREKILNIFENYPIVKKAYTDNVPKNFKEPEFWARFFSSKLFRKLRGEKIMQNDRGDVIIDRYLTLDQEFDRKDDDMLLHPVKKIIDLDGNIQDDPVVRGNRPDFTMQPGVDINGNSDGTVDILKGMNRLSEKMIMALKNEYSRTNLQNKSNITNDEEDE------------------------DNDERNELKIDDLNESYKTNYAIIHLKRN---AHEKTTDNDAKSSADSIKNADLKVSNQQMLQQLSLVMDNLINKLDLNQVVPNNEVSNKINKRVITAIKINAKQAKHNNVNSALGSFVDNTSQANELEVKSTLPIDLLESCRMLHTTCCEFLKHFYIHFQSGEQKQASTVKKLYNHLKDCIEKLNELFQDVLNGDGESMSNTCTAYLKPVLNSITLATHKYDEYFNEYNNNSN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::*.: :* : :* .* : :: : :* . : * * . : . . : . * . ..: . . ::. : : : : : . *.* .:*: :: :* : *:::::: *:. :...***:.: . .*.:* .*: ::* :.. * :. **: : * **..** ** : :.** ::.* ***::**.*: *:: * : . *:: : :: :. . .*: .: :: * *: .* *. . . ::*:..: *.* . . . .. : ...: : : . . .* ..:..*: .:.: : . :*. : . . .: . . .: . . . *. *::: . : . :* *: . : *: : *:*:**: * .: :: . *: *:: : : .. . ::: :*.: .:.. . ", "identical_positions": 67, "similar_positions": 197, "identity": "9.96%" }, { "cls_id": "homologset.agr.RGD:1308226", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GHE9-1", "uniprot_id": "A0A8I6GHE9_RAT", "id": "A0A8I6GHE9-1", "name": "Leucine-rich repeat and guanylate kinase domain-containing protein", "aln": "MATFEGSPSRWKGTRFQRSLGASRAVAQAILSLTDKEPQKRWPTFPMGLRSKGTFRSASSYLLHQLIHRSHEAEVEQEE-QQEEGE-SEESEESEMQNLEDEYDGVLREENVADALDGLGWSGRGTEQVYRNLNLSHCELIDVSILSGYVHLQKLNLSGNRIEDLSCVSCMPYLLELNASQNRLTTFFNFKPPQNLKKVDFSSNQISEMYDLSAYHTLTQLILDNNEIEEITGLEKCISLTHLSLAGNRITTIKGLGTLPIKVLSVSNNQIETITGLEELKALQNLDLSHNQISSLHGLENHDLLEVINLEDNKIKELSEIEYIENLPILRVLNLLRNPIQTKPEYWFFVIFMLLRLTELDQQKIKVEEKVYAVNKYDPPPEVVAAQDHMTHVVNSMSQPQRIFDSTLPSLDAPYPMLILTGPEACGKRELAHRLCRQFSTYFRYGACHTTRPPYFGEGDRVDYHFVSQEVFDEMLSMGKFILTFNYGNHNYGLNRDTVEGIARDGLASCIHMELEGIRSLKYSYFEPRYILVVPMDKEKYEGYLRRKGLFSRAEIEIAVSRVDLYVKVNRKFPGYFDAVINADDLDIAYQKLSELIREYLGLTETAKKGLAPTAGASSSKKTVSGVPAHLVPSPRRLARLQADGQKTEAFLEVQPHAMIPENQNPTLPQSQDLTEEGEAPKKEASPSHLDLPQQTQDISPKVKEEDGQPANLPPKITTETEGPEDEPVPPVLEAGQSSTMASQEPPQHPAPAPPLSPQLDQDKESGETKVTPNNPALSEPAQGPDPASVSPQRVQDEGAESANLASSSSTHNLPEDPSHAEIEKPTVGSQPSLKEETPKAEVMRASTPYPEIPPPQDSSTKVREQPVALLPRSRLAPTRLPQPQTLAPLQSRRPTPKLLSPSREEALGTSSEQTPNPSPRSLPTQDGDPSKLPPISPPQSKPPQNPSPHAVHSPQQAQVEKGSEVKLPLISPPVQEQALQHTPKPPQEEEAPTVRLPNIPAPSTEPHLPQNTEPRPASKPARERKTPKVGRASSKKVLDLQATPHSQELTKQKGARKKTLTQRETAKELPHPKKMPIGNSQTAQQPESHSRPTPRNESDALDFRSSPGHTEPVSADPQNREKNRKAHNPRKKAQTNPTPKDASQSTRTSPNGEMSEGLTQGNETALSEDQPTREGQPPQATDQSAQDIAVPSQLRAKESQAQRNTRETRQSYAQRHSILVSKQQSKEKRTRKNGGVPQDRSPAAPQNEVSQEDPGSQTGRLRARGSQSIKV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D5S7-1", "uniprot_id": "LRGUK_MOUSE", "id": "Q9D5S7-1", "name": "Leucine-rich repeat and guanylate kinase domain-containing protein", "aln": "MAAFERNPSRWKGTRFRRGLGASRIAAQAILSLTEKQSQGRWPSFPLGLKSKGTFRSASSYLLHQLIHRSHEAEAEQEEKQQEDGE-SEESEESEMQNLEDKYDGILREETVAEAITGLGWSGRGTEQVYLNLNLSHCELVDISILCGYVHLQKLNLSGNRIEDLSCVSCMPYLLELNASQNKLTTFFNFKPPQNLKKVDFSSNLISEMYDLSAYHTLTQLILDNNEIEEITGLENCISLTHLSLAGNKITTIKGLGTLPIKVLSLSNNMIETITGLEELKALQNLDLSHNQISSLQGLENHDLLEVINLEDNKIKELSEIEYIENLPILRVLNLLRNPIQTKPEYWFFVIYMLLRLTELDQQKIKVEEKVFAVNKYDPPPEVVAVQDHMTHVVNSMSQPQRIWDSTLPSLDAPYPMLILTGPAACGKRELAHRLCRQFSTYFRYGACHTTRPPYFGEGDRVDYHFISQEVFDEMLNMGKFILTFNYGNHNYGLNRDTIEGIARDGLASCIHMELEGVRSLKYSYFEPRYILVVPMDKEKYEGYLRRKGLFSRAEIEIAVSRVDLYVKVNQKYPGYFDAVINADDMDIAYQKLSELIREYLGLTETAAKTLAPTADTKTS------------------------------YLKCEDYS-----------------------RKSSTVEFLDS------------TDRNYFTKLWAKLSSKKSPVERESLHRQHEAARQALMG---------------------------KTPRDHTLLFQRGPVPIPTVSGQQ-------YFATIDELQKTFELSDD-----LFKTPSGTYP---ETSKDSNISKRYSTYFHT-----------------CPWSKELPFQLPEG------------------------GISS----RPGSAGSDEVDGALKALRVASSMQEKVAQHKRLSAITIMD--------------------------------------------PGSNTKPTLPP----------------------------------------------------------IPHGRR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96M69-1", "uniprot_id": "LRGUK_HUMAN", "id": "Q96M69-1", "name": "Leucine-rich repeat and guanylate kinase domain-containing protein", "aln": "MATSERALLRTRAASLLRGLGRSRTGARSLQFRAEKERQPCWS-FPMGQKTKGSSNIASSYLLQQLMHRYQELDSDGDEDQGEGEAGSEESSESEMLNLEEEFDGVLREEAVAKALHHLGRSGSGTEQVYLNLTLSGCNLIDVSILCGYVHLQKLDLSANKIEDLSCVSCMPYLLELNASQNNLTTFFNFKPPKNLKKADFSHNQISEICDLSAYHALTKLILDGNEIEEISGLEMCNNLIHLSLANNKITTINGLNKLPIKILCLSNNQIEMITGLEDLKALQNLDLSHNQISSLQGLENHDLLEVINLEDNKIAELREIEYIKNLPILRVLNLLENPIQEKSEYWFFVIFMLLRLTELDQKKIKVEEKVSAVNKYDPPPEVVAAQDHLTHVVNSVMQPQRIFDSTLPSLDAPYPMLILAGPEACGKRELAHRLCRQFSTYFRYGACHTTRPPYFGEGDRVDYHFISQDVFDEMVNMGKFILTFSYGNHKYGLNRDTVEGIARDGLASCIHMEIEGVRSLKYSYFEPRYILVVPMNKEKYEGYLRRKGLFSRAEIEFAVSRVDLYIKINQNFPGYFDEVINADDLDVAYQKLSQLIREYLGLTEEPAKSLATTADVKTS------------------------------HLKPEAHP-----------------------TKYISSNMGDFLHS---------TDRNYLIKFWAKLSAKKTPAERDSIHRQHEAARQALMG---------------------------RIRPDHTLLFQRGPVPAPLTSGLH-------YYTTLEELWKSFDLCED-----YFKPPFGPYP---EKSGKDSLVSMKCSLFRF-----------------CPWSKELPFQPPEG------------------------SISS---HLGSGASDSETEETRKALPIQSFSHEKESHQHRQHSVPVISR-------------------------------------------PGSNVKPTLPP----------------------------------------------------------IPQGRR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TU23-1", "uniprot_id": "A0AB32TU23_DANRE", "id": "A0AB32TU23-1", "name": "Leucine-rich repeat and guanylate kinase domain-containing protein", "aln": "MSVRSGSVSDRTPAHLPVSLCAIS----------------------------GFYRMTFYWHLN----------------------------------------------RISDCVWPQGR-----------------DLKNVSILCNYIYLQKLELPYNKIKDLSCVSHMPYLITLDASHNQLTDFFGFQPPKNLKEVNFSHNQMTAMKDLSAYSSLTKLILDHNSFSVIRGLEKCKRLSHLSLAHNNISRIRGLDHLPLRELCLAGNMINKIENLQTLHNLQVLDLSCNRIQSLTGLQNLRFLGTVNLESNLITEIKEAAHLHDLILLREINLLKNPVQDHDDYRIAVIFLLQHLILLDKQTVTAEEKVAAVNKYDPPLEVVAARDHMTHLVYQLMQPQVIFDSTLPSLDAPYPMLVLTGPQACGKRELAHKLCQEFSDYFAYGACHTTRGPYFGEEDGLDYHFVTEEEFHNMIQMGQFIQTMQYGGHWYGLSRESIERVAREGLACCVHMELEGVFSLKNSYFEPRYVLLIPSVVDNYVLFLKARGFYSNAQMETAVSRIDLYARINRERPGFFDSIIPCDDRAEAYRSLKQLVKEYLGLEEHSGGGDSSSITPDNTS-----------------------------TNTTGELP---------------------AASATESTDLMDS------------YSRNYQKKIQANMTPQRT--EMASNHRRLQQIREALSG---------------------------KSPGAYAELFQRSVPAAPSSLASQ--------SHPPAGPSSSPVRPAG-----LSAPNLSEDSS-SEESRASSGLSMRSSAGVF--------------------SAESPARGSDA------------------------GSGP----NIEPLDISMLGQDRDSLRGLTPDAPRPASDRVSPTHPSSPGR------------------------------------------PGANVKPVLPP----------------------------------------------------------IPSGRKTNDSGSKQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:. . : : .* * . : : *: ::..: * :* ::***..*::****:*. *:*:****** ****: *:**:*.** **.*:**:***:.:** * :: : ***** :**:**** *.:. * *** * * ***** *.*: *.**. **:: *.::.* *: * .*: *: ** **** *:*.** **:* :* .:***.* * *: * ::.:* :** :***.**:* : :* : **::* :* **::.:..**** ******** ****.:**:**:* .: *** *:**************:*:** *********:**::** ** ******** ***** * :****:::: *.:*:.**:** *:.**.* ***.*:::* :**:***.*:***:**: *** *******:*::* ::* :*: :*::*.*::* ****:*** ::*:: **:** :* .** **:.*.:*::***** * . :.: ..: . : . * . . :: .:::.: * . : :.: . : . * : . . * . : .: . . . . * : . . * * : .: . .. . . * : : . . : *....:* ** :* :: ", "identical_positions": 274, "similar_positions": 211, "identity": "21.54%" }, { "cls_id": "homologset.agr.RGD:1308227", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z8T6-1", "uniprot_id": "D3Z8T6_RAT", "id": "D3Z8T6-1", "name": "", "aln": "MKTGCAAGSPGNEWVFFSSDERSTRSRKTMSNGALQRSAVLSALVLLRAVTGFSGDGKAIWDKKQYVSPVNPGQLFLYDTFPKNFSWGVGTGAFQVEGSWKADGRGPSIWDRYVDSHLRGVN---STDRSTDSYVFLEKDLLALDFLGVSFYQFSISWPRLFPNGTVAAVNAKGLQYYRALLDSLVLRNIEPIVTLYHWDLPLTLQEEYGGWKNATMIDLFNDYATYCFQTFGDRVKYWITIHNPYLVAWHGFGTGMHAPGEKGNLTAVYTVGHNLIKAHSKVWHNYDKNFRPHQKGWLSITLGSHWIEPNRTENMEDVINCQHSMSSVLGWFANPIHGDGDYPEFMKTS--SVIPEFSEAEKEEVRGTADFFAFSFGPNNFRPSNTVVKMGQNVSLNLRQVLNWIKLEYDNPRILISENGWFTDSYIKTEDTTAIYMMKNFLNQVLQAIKFDEIQVFGYTAWTLLDGFEWQDAYTTRRGLFYVDFNSEQKERKPKSSAHYYKQIIQDNGFPLQESTPDMKGQFPCDFSWGVTESVLKPEFTVSSPQFTDPHLYVWNVTGNRLLYRVEGVRLKTRPSQCTDYVSIKKRVEMLAKMKVTHYQFALDWTSILPTGNLSKINRQVLRYYRCVVSEGLKLGISPMVTLYHPTHSHLGLPMPLLSSGGWLNTNTAKAFQDYAGLCFQELGDLVKLWITINEPNRLSDMYNRTSNDTYRAAHNLMIAHAQVWHLYDRQYRPVQHGAVSLSLHSDWAEPANPYVESHWKAAERFLQFEIAWFADPLFKTGDYPLAMKEYIA--SKKQRGLSSSVLPRFTLKESRLVKGTIDFYALNHFTTRFVIHKQLNTN----RSVADRDVQFLQDITRLSSPSR----LAVTPWGMRKLLGWIRRNYRDMDIYVTANGIDDLALEDDQIRKYYLEKYVQEALKAYLIDKVKIKGYYAFKLTEEKSKPRFGFFTSDFKAKSSVQFYSKLISSSGFSSENRSPACGQPPEDTECAICSFLTQKKPLIFFGCCFISTLAALLSITIFHHRKRRKFQKARNLQNIPLKKGHSRVFS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99N32-1", "uniprot_id": "KLOTB_MOUSE", "id": "Q99N32-1", "name": "Beta-klotho", "aln": "MKTGCAAGSPGNEWIFFSSDERNTRSRKTMSNRALQRSAVLSAFVLLRAVTGFSGDGKAIWDKKQYVSPVNPSQLFLYDTFPKNFSWGVGTGAFQVEGSWKTDGRGPSIWDRYVYSHLRGVN---GTDRSTDSYIFLEKDLLALDFLGVSFYQFSISWPRLFPNGTVAAVNAQGLRYYRALLDSLVLRNIEPIVTLYHWDLPLTLQEEYGGWKNATMIDLFNDYATYCFQTFGDRVKYWITIHNPYLVAWHGFGTGMHAPGEKGNLTAVYTVGHNLIKAHSKVWHNYDKNFRPHQKGWLSITLGSHWIEPNRTDNMEDVINCQHSMSSVLGWFANPIHGDGDYPEFMKTG--AMIPEFSEAEKEEVRGTADFFAFSFGPNNFRPSNTVVKMGQNVSLNLRQVLNWIKLEYDDPQILISENGWFTDSYIKTEDTTAIYMMKNFLNQVLQAIKFDEIRVFGYTAWTLLDGFEWQDAYTTRRGLFYVDFNSEQKERKPKSSAHYYKQIIQDNGFPLKESTPDMKGRFPCDFSWGVTESVLKPEFTVSSPQFTDPHLYVWNVTGNRLLYRVEGVRLKTRPSQCTDYVSIKKRVEMLAKMKVTHYQFALDWTSILPTGNLSKVNRQVLRYYRCVVSEGLKLGVFPMVTLYHPTHSHLGLPLPLLSSGGWLNMNTAKAFQDYAELCFRELGDLVKLWITINEPNRLSDMYNRTSNDTYRAAHNLMIAHAQVWHLYDRQYRPVQHGAVSLSLHCDWAEPANPFVDSHWKAAERFLQFEIAWFADPLFKTGDYPSVMKEYIA--SKNQRGLSSSVLPRFTAKESRLVKGTVDFYALNHFTTRFVIHKQLNTN----RSVADRDVQFLQDITRLSSPSR----LAVTPWGVRKLLAWIRRNYRDRDIYITANGIDDLALEDDQIRKYYLEKYVQEALKAYLIDKVKIKGYYAFKLTEEKSKPRFGFFTSDFRAKSSVQFYSKLISSSGLPAENRSPACGQPAEDTDCTICSFLVEKKPLIFFGCCFISTLAVLLSITVFHHQKRRKFQKARNLQNIPLKKGHSRVFS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86Z14-1", "uniprot_id": "KLOTB_HUMAN", "id": "Q86Z14-1", "name": "Beta-klotho", "aln": "MKPGCAAGSPGNEWIFFSTDEITTRYRNTMSNGGLQRSVILSALILLRAVTGFSGDGRAIWSKNPNFTPVNESQLFLYDTFPKNFFWGIGTGALQVEGSWKKDGKGPSIWDHFIHTHLKNVS---STNGSSDSYIFLEKDLSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLDALVLRNIEPIVTLYHWDLPLALQEKYGGWKNDTIIDIFNDYATYCFQMFGDRVKYWITIHNPYLVAWHGYGTGMHAPGEKGNLAAVYTVGHNLIKAHSKVWHNYNTHFRPHQKGWLSITLGSHWIEPNRSENTMDIFKCQQSMVSVLGWFANPIHGDGDYPEGMRKKLFSVLPIFSEAEKHEMRGTADFFAFSFGPNNFKPLNTMAKMGQNVSLNLREALNWIKLEYNNPRILIAENGWFTDSRVKTEDTTAIYMMKNFLSQVLQAIRLDEIRVFGYTAWSLLDGFEWQDAYTIRRGLFYVDFNSKQKERKPKSSAHYYKQIIRENGFSLKESTPDVQGQFPCDFSWGVTESVLKPESVASSPQFSDPHLYVWNATGNRLLHRVEGVRLKTRPAQCTDFVNIKKQLEMLARMKVTHYRFALDWASVLPTGNLSAVNRQALRYYRCVVSEGLKLGISAMVTLYYPTHAHLGLPEPLLHADGWLNPSTAEAFQAYAGLCFQELGDLVKLWITINEPNRLSDIYNRSGNDTYGAAHNLLVAHALAWRLYDRQFRPSQRGAVSLSLHADWAEPANPYADSHWRAAERFLQFEIAWFAEPLFKTGDYPAAMREYIA--SKHRRGLSSSALPRLTEAERRLLKGTVDFCALNHFTTRFVMHEQLAGS----RYDSDRDIQFLQDITRLSSPTR----LAVIPWGVRKLLRWVRRNYGDMDIYITASGIDDQALEDDRLRKYYLGKYLQEVLKAYLIDKVRIKGYYAFKLAEEKSKPRFGFFTSDFKAKSSIQFYNKVISSRGFPFENSSSRCSQTQENTECTVCLFLVQKKPLIFLGCCFFSTLVLLLSIAIFQRQKRRKFWKAKNLQHIPLKKGK-RVVS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VV98-1", "uniprot_id": "Q9VV98_DROME", "id": "Q9VV98-1", "name": "Cytosolic beta-glucosidase", "aln": "-----------------------------------MMQIILPLFVLTASCLG---------------SPVSQT-----RRFPNDFLWGVGSSSYQIEGGWNADDKGESIWDFLTHTHPEKIVDRSNGDVSADSYHQWKRDVQMVKELHVGTYRFSLSWPRIMPGGYMNHVSTAGIKYYSNLIDELLRYNITPMVTIYHWELPQKLQELGG-WTNPEIIPLFKDYARLVLEMYGDRVKIWTTVNEPWHVCEHGYGVDYMAPSYNYPGIPAYLCGHNLLKAHAEVVHMYRELFQPRQGGRMGITLDTSWPEPRDPNSAEDREASERAMQFYVGWFGHPIFS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHGNYPKVMIERIRNLSKEQGFGARSRLPEFTTEEIHRIRGTSDFFGINSYTSNLVTSNGHNNTGKFPVPSFNHDMGVVESQEGVDWPGSGSVWLKVYPKGMYNLLMWIHREYNAPEIIVTENGVSDRGGLEDYARVDYYNLYLSAVLDA-MEDGANISGYIAWSLMDS----------YEWKAGFSEKFGLYHVDFN-SPQRTRTPKISARVFAQLCKTNTIDWSYRPKLDEEQQLVAMAQLPAEARTSGASGAVSWSLMGILLLALLR--------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :*. ::* : * :**. **::* **:*:.: *:**.*: *.:* **** :* . : . : *:*** ::*: :. : *. *:**:****::*.* : ..: *::** *:* *: ** *:**:***:** *** * *.* :* :*:*** :: :***** * *:::*: *. **:*.. **. : ..* ****:***::* * * *:*:* * :.***.: * **. .:. * .:::* :***.:**.. * *:** .* * * **.: : * **.:* * : ::** ** .:* :*:.:* : . ::*: .::. :. * * * * *: :** *::*:* :* :* .*:.* . :* * * *:. .*.* : * ..*.** *:.* :. :::* * :* :. . .. :. . * : . :* : :.: . .: * *: ", "identical_positions": 161, "similar_positions": 163, "identity": "15.22%" }, { "cls_id": "homologset.agr.RGD:1308228", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ERF3-1", "uniprot_id": "SKI8_MOUSE", "id": "Q9ERF3-1", "name": "Superkiller complex protein 8", "aln": "MTNQYSILFKQEQAHDDAIWSVAWETN---------------------KKEN--IETVVTGSLDDLVKVWKWR----DERLELQWSLEGHQLGVVSVDISHTLP-------IAASSSLDAHIRLWDLENGKQMKSIDAGPVD----------AWTLAFSPDSQYLATG----------THMGKVNIFGVES--------------GKKEYSLDTR-GKFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEG------HAMPIRSLTFSPDSQLLVTASDD---GYIKIYDVQHANLAGTLSG-------------HASWVLNVAFCPDDTHFVSSSSDKSVKVWDVGTRTCIHTFFDHQD---------------------QVWGVKYNGNGSKIVSVGDDQEIHVYDCPI------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4V7A0-1", "uniprot_id": "SKI8_RAT", "id": "Q4V7A0-1", "name": "Superkiller complex protein 8", "aln": "MTNQYSILFKQEQAHDDAIWSVAWETN---------------------KKEN--IETVVTGSLDDLVKVWKWR----DERLELQWSLEGHQLGVVSVDISHTLP-------IAASSSLDAHIRLWDLENGKQMKSIDAGPVD----------AWTLAFSPDSQHLATG----------THMGKVNIFGVES--------------GKKEYSLDTR-GKFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEG------HAMPIRSLTFSPDSQLLVTASDD---GYIKIYDVQHANLAGTLSG-------------HASWVLNVAFCPDDTHFVSSSSDKSVKVWDVGTRTCIHTFFDHQD---------------------QVWGVKYNGNGSKIVSVGDDQEIHVYDCPI------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9GZS3-1", "uniprot_id": "SKI8_HUMAN", "id": "Q9GZS3-1", "name": "Superkiller complex protein 8", "aln": "MTNQYGILFKQEQAHDDAIWSVAWGTN---------------------KKEN--SETVVTGSLDDLVKVWKWR----DERLDLQWSLEGHQLGVVSVDISHTLP-------IAASSSLDAHIRLWDLENGKQIKSIDAGPVD----------AWTLAFSPDSQYLATG----------THVGKVNIFGVES--------------GKKEYSLDTR-GKFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEG------HAMPIRSLTFSPDSQLLVTASDD---GYIKIYDVQHANLAGTLSG-------------HASWVLNVAFCPDDTHFVSSSSDKSVKVWDVGTRTCVHTFFDHQD---------------------QVWGVKYNGNGSKIVSVGDDQEIHIYDCPI------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6P5M2-1", "uniprot_id": "SKI8_DANRE", "id": "Q6P5M2-1", "name": "Superkiller complex protein 8", "aln": "MSTQYSILFKQEHAHEDAIWTAAWGRS---------------------EKDG--SETIVTGSLDDLVKVWKWS----DEKLELQWTLEGHQLGVVSVNISQNGA-------IAASSSLDAHIRLWDLETGKQIKSMDAGPVD----------AWTVAFSPDSKYIATG----------SHLGKVNIFGVES--------------GKKEHSLDTR-GKFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEG------HAMPIRSLTFSPDSQLLVTASDD---GYIKIYDVQHANLAGTLSG-------------HGSWVLSVAFSPDDTHFVSSSSDKSIKVWDTSSRSCVNTFFDHQD---------------------QVWSVKYNPTGSKIVSAGDDRAIHIYDCPM------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9XZ19-1", "uniprot_id": "Q9XZ19_DROME", "id": "Q9XZ19-1", "name": "IFT122/SMU1 beta-propeller domain-containing protein", "aln": "---MFSVLHKEENAHDSQLWACTWGRDTAASDPDDAVVEPEENPFDFDKKEARPKDFLVTGGLDDLVKVWDLQE---DNTLKLRHKLKGHALGVVSVAVSSDGQ-------TIASSSLDSTMCLWDARSGDKKHLLSFGPVD----------LWTVQFSPCNKYVISG----------LNDGKISMYSVET--------------GKAEQTLDAQNGKYTLSIAYSPDGKYIASGAIDGIITIFDVAAGKVVQTLEG------HAMPVRSLCFSPNSQLLLTASDD---GHMKLYDVTHSDVVGTLSG-------------HASWVLCVAFSEDGKHFASSSSDNSVKIWDTSERKCLHTFAEHTD---------------------QVWGVRYSPGNDKVASASEDKSLNIYYCPPNAIV--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q02793-1", "uniprot_id": "SKI8_YEAST", "id": "Q02793-1", "name": "Antiviral protein SKI8", "aln": "MSKVFIATANAGKAHDADIFSVSACNS-----------------------------FTVSCSGDGYLKVWDNKLLDNENPKDKSYSHFVHKSGLHHVDVLQAIERDAFELCLVATTSFSGDLLFYRITREDETKKVIFEKLDLLDSDMKKHSFWALKWGASNDRLLSHRLVATDVKGTTYIWKFHPFADESNSLTLNWSPTLELQGTVESPMTPS--QFATSVDISERG-LIATGFNNGTVQISELSTLRPLYNFESQHSMINNSNSIRSVKFSPQGSLLAIAHDSNSFGCITLYETEFGERIGSLSVPTHSSQASLGEFAHSSWVMSLSFNDSGETLCSAGWDGKLRFWDVKTKERITTLNMHCDDIEIEEDILAVDEHGDSLAEPGVFDVKFLKKGWRSGMGADLNESLCCVCLDRSIRWFREAGGK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :**: ::: : . *: . *. :***. :: . . * *: * : *::*:.. : :: .: : : :* *:: :.. .. : : *. :. *: *. * .: . :: *: * * :*:* :* : * :::: : : .:*. :: .:**: ***:..** * *. * :.:*:. ..: *:** *.***: ::* .. : *:. * .::.**. : : *: * * *:.*:: . : .: . * ", "identical_positions": 55, "similar_positions": 110, "identity": "12.82%" }, { "cls_id": "homologset.agr.RGD:1308229", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BSM7-1", "uniprot_id": "LAT3_MOUSE", "id": "Q8BSM7-1", "name": "Large neutral amino acids transporter small subunit 3", "aln": "MAPTLKQAYRRRWWMACTAVVENLFFSAVLLGWASLLIMLKKEGFYSSLCPAENRTNTTQDEQHQWTSCDQQEKMLNLGFTIGSFLLSATTLPLGILMDRFGPRPLRLVGSACFAASCTLMALASRDTEVLSPLIFLALSLNGFAGICLTFTSLTLPNMFGNLRSTFMALMIGSYASSAITFPGIKLIYDAGVPFTVIMFTWSGLACLIFLNCALNWPAEAFPAPEEVDYTKKIKLIGLALDHKVTGDRFYTHVTIVGQRLSQKSPSLEEGADAFISSPDIPGTSEETPEKSVPFRKS-----LCSPIFLWSLVTMGMTQLRVIFYMGAMNKILEFIVTGGKERETNEQRQKVEETVEFYSSIFGVMQLLCLLTCPLIGYIMDWRIKDCVDAPTEGTLNENASFGDARDGASTKFTRPRYRKVQKLTNAINAFTLTNILLVGFGIACLIKN-LHLQLLAFVLHTIVRGFFHSACGGLYAAVFPSNHFGTLTGLQSLISAVFALLQQLLFMAMVGPLHGDPFWVNLGLLLLSFLGFLLPSYLYYYRSRLQREYATNLVDPQKVLNTSKVAT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AC62-1", "uniprot_id": "A0A8I6AC62_RAT", "id": "A0A8I6AC62-1", "name": "", "aln": "MAPTLKQAYRRRWWMACTAVVENLFFSAVLLGWASLLIMLKKEGFYSSLCPAENRTNTTQDEQ-QWISCDQQEEMLNLGFTIGSFLLSATTLPLGILMDRFGPRPLRLVGSACFAASCTLMALASRDTEVLSPLIFLALSLNGFAGICLTFTSLTLPNMFGNLRSTFMALMIGSYASSAITFPGIKLIYDAGVSFMVIMFTWSGLACLIFLNCALNWPAEAFPAPEEVDYTKKIKLIGLALDHKVTGDRFYTHVTIVGQRLSQKTPSLEEGTDGFISSSDIPGTSEKTPEKSVPFRKS-----LCSPIFLWSLVTMGMTQLRVIFYMGAMNKILEFLVTGGKECETNEQRQKVEETVEFYSSIFGVMQLLCLLTCPLIGYIMDWRIKDCVDDPTEGTLNESASFGDARDGTITKFTKPRYRKIQKLTNAINAFTLTNILLVGFGITCLIKN-LHLQLVAFVLHTVVRGFFHSACGGLYAAVFPSNHFGTLTGLQSLISAVFALLQQLLFMAMVGPLHGDPFWVNLGLLILSLLGFLLPSYLYYYRSRLEREYATNLLDPQKVLNTSKVAT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75387-1", "uniprot_id": "LAT3_HUMAN", "id": "O75387-1", "name": "Large neutral amino acids transporter small subunit 3", "aln": "MAPTLQQAYRRRWWMACTAVLENLFFSAVLLGWGSLLIILKNEGFYSSTCPAESSTNTTQDEQRRWPGCDQQDEMLNLGFTIGSFVLSATTLPLGILMDRFGPRPVRLVGSACFTASCTLMALASRDVEALSPLIFLALSLNGFGGICLTFTSLTLPNMFGNLRSTLMALMIGSYASSAITFPGIKLIYDAGVAFVVIMFTWSGLACLIFLNCTLNWPIEAFPAPEEVNYTKKIKLSGLALDHKVTGDLFYTHVTTMGQRLSQKAPSLEDGSDAFMSPQDVRGTSENLPERSVPLRKS-----LCSPTFLWSLLTMGMTQLRIIFYMAAVNKMLEYLVTGGQEHETNEQQQKVAETVGFYSSVFGAMQLLCLLTCPLIGYIMDWRIKDCVDAPTQGTV-----LGDARDGVATKSIRPRYCKIQKLTNAISAFTLTNLLLVGFGITCLINN-LHLQFVTFVLHTIVRGFFHSACGSLYAAVFPSNHFGTLTGLQSLISAVFALLQQPLFMAMVGPLKGEPFWVNLGLLLFSLLGFLLPSYLFYYRARLQQEYAANGMGPLKVLSGSEVTA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q04991-1", "uniprot_id": "FMP42_YEAST", "id": "Q04991-1", "name": "Protein FMP42", "aln": "----MTSTRTLRYAQVACACIWCLFSAGIIFGFAALKPILISEGVYHELCDPKDGD---------RLLCTAQDLKLNFIFALSATVTNIMALPVGKILDMYGPRVCGIIG-SCLLFLASGNFISAKHLVSLWDPYLVGYTLLAVAGPFVFISCFQLANSFPQRSGTVLALLTGSFDSSSALFLLYRLLYQNWFPTLNVSRFFTLYLIVPVFILACQLTIMPHSSYKTVNHIAKIAVEGLDENGRLIEGDTGSGIIPD-EQERQSLIAIEREEDSIPSRPQRRKSVLETYVEDKLQKKSGGIFGVLHGKSAYEQIKSPWFYLMLLFALVAMLRINYFIATVRTQEEYLLNDP--DLALKLNSIFDMLLPLGGAVSIPFIGLLLDH------------------------------------------TDTLSTLTILFTTSTAIGVFGLIPNSFTWNLIGIVLLVVYRPFYYTVVSDYSSKVFGFDTFGTVYGLLSCICGIFNMSQNLLDKWTHTTFNMNPFPINLTLVILTVV--FSLTLTFYIRSQILPKPVN-----ERGLSSNYQTI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .: *: .. * : ** :.:::*:.:* :* .**.* . * .:. * *: **: *::.: : . :**:* ::* :*** ::* :*: .: ::::. * ::. :* ...* : ::.: *.* * : .*.:**: **: **: * :*:*: .. : :: : .: : : . ...: : *:: ** : ** : :: . : : :: *. ::* *.: * : : : .. :** : :. :. * ::* : *: :: ::.* : * : :: : * . : * :: *:** ::* *:::.::*: ..:*: ** * : ::: :** .: * *:::. .. : ** : ***: ** * *..:* : *: * .:: :** :** *::::.: : : :* *::: : . : *. . : ", "identical_positions": 93, "similar_positions": 188, "identity": "16.32%" }, { "cls_id": "homologset.agr.RGD:1308230", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Y262-1", "uniprot_id": "EIF3L_HUMAN", "id": "Q9Y262-1", "name": "Eukaryotic translation initiation factor 3 subunit L", "aln": "MSYPADDYESEAAYDPYAYPSDYDMHTGDPKQDLAYERQYE-QQTYQVIPEVIKNFIQYFHKTVSDLIDQKVYELQASRVSSDVIDQKVYEIQDIYENSWTKLTERFFKNTPWPEAEAIAPQVGNDAVFLILYKELYYRHIYAKVSGGPSLEQRFESYYNYCNLFNYILNADGPAPLELPNQWLWDIIDEFIYQFQSFSQYRCKTAKKSEEEIDFLRSNPK-IWNVHSVLNVLHSLVDKSNINRQLEVYTSGGDPESVAGEYGRHSLYKMLGYFSLVGLLRLHSLLGDYYQAIKVLENIELNKKSMYSRVPECQVTTYYYVGFAYLMMRRYQDAIRVFANILLYIQRTKSMFQRTTYKYEMINKQNEQMHALLAIALTMYPMRIDESIHLQLREK-YGDKMLRMQKGDPQVYEELFSYSCPKFLSPVVPNYDNVHPNYHKEPFLQQLKVFSDEVQQQAQLSTIRSFLKLYTTMPVAKLAGFLDLTEQE-----FRIQLLVFKHKMKNLVWTSGISALDGEFQSASEVDFYIDKDMIHIADTKVARRYGDFFIRQIHKFEELNRTLKKMGQRP-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8QZY1-1", "uniprot_id": "EIF3L_MOUSE", "id": "Q8QZY1-1", "name": "Eukaryotic translation initiation factor 3 subunit L", "aln": "MSYPADDYESEAAYDPYAYPGDYDMHTGDPKQDLAYERQYE-QQTYQVIPEVIKNFIQYFHKTVSDLIDQKVYELQASRVSSDVIDQKVYEIQDIYENSWTKLTERFFKNTPWPEAEAIAPQVGNDAVFLILYKELYYRHIYAKVSGGPSLEQRFESYYNYCNLFNYILNADGPAPLELPNQWLWDIIDEFIYQFQSFSQYRCKTAKKSEGEMDFLRSNPK-VWNVHSVLNVLHSLVDKSNINRQLEVYTSGGDPESVAGEYGRHSLYKMLGYFSLVGLLRLHSLLGDYYQAIKVLENIELNKKSMYSRVPECQVTTYYYVGFAYLMMRRYQDAIRVFANILLYIQRTKSMFQRTTYKYEMINKQNEQMHALLAIALTMYPMRIDESIHLQLREK-YGDKMLRMQKGDPQVYEELFSYACPKFLSPVVPNYDNVHPNYHKEPFLQQLKVFSDEVQQQAQLSTIRSFLKLYTTMPVAKLAGFLDLTEQE-----FRIQLLVFKHKMKNLVWTSGISALDGEFQSASEVDFYIDKDMIHIADTKVARRYGDFFIRQIHKFEELNRTLKKMGQRP-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3V7G9-1", "uniprot_id": "G3V7G9_RAT", "id": "G3V7G9-1", "name": "Eukaryotic translation initiation factor 3 subunit L", "aln": "MSYPADDYESETAYDPYAYPGDYDMHTGDPKQDLAYERQYE-QQTYQVIPEVIKNFIQYFHKTVSDLIDQKVYELQASRVSSDVIDQKVYEIQDIYENSWTKLTERFFKNTPWPEAEAIAPQVGNDAVFLILYKELYYRHIYAKVSGGPSLEQRFESYYNYCNLFNYILNADGPAPLELPNQWLWDIIDEFIYQFQSFSQYRCKTAKKSEEEIDFLRSNPK-IWNVHSVLNVLHSLVDKSNINRQLEVYTSGGDPESVAGEYGRHSLYKMLGYFSLVGLLRLHSLLGDYYQAIKVLENIELNKKSMYSRVPECQVTTYYYVGFAYLMMRRYQDAIRVFANILLYIQRTKSMFQRTTYKYEMINKQNEQMHALLAIALTMYPMRIDESIHLQLREK-YGDKMLRMQKGDPQVYEELFSYACPKFLSPVVPNYDNVHPNYHKEPFLQQLKVFSDEVQQQAQLSTIRSFLKLYTTMPVAKLAGFLDLTEQE-----FRIQLLVFKHKMKNLVWTSGISALDGEFQSASEVDFYIDKDMIHIADTKVARRYGDFFIRQIHKFEELNRTLKKMGQRP-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7T2A5-1", "uniprot_id": "EIF3L_DANRE", "id": "Q7T2A5-1", "name": "Eukaryotic translation initiation factor 3 subunit L", "aln": "MSYPAE--EEDVNYDPYSYPNDYDYHTGDPKADLAYERQYEHQQTYHVIPEVIKNFLQYFHKTISDLIDQKVYELQANRVSSESIEQKIYEIQDVYENSWNKLTDRFFKTSPWPEAEAIASLVGNDAVFLILYKELYYRHIYAKVSGGPTLDQRFESYYNYCNLFNYILNADGPAPLELPNQWLWDIIDEFIYQFQSFSQYRCKTAKKSEEEIEFLRNNPK-IWNVHSVLNVLHSLVDKSNINRQLEVYTSGGDPESVAGEYGRHSLYKMLGYFSLVGLLRLHSLLGDYYQAIKVLENIELNKKSMYSRVPECQITTYYYVGFAYLMMRRYQDAIRVFANILLYIQRTRNMFQRTTYKYEMINKQNEQMHGLLAIALTMYPMRIDESIHTQLREK-YGDKMLRMQKGDLQVFEELFSFACPKFLSPVVPNYENVHPNYHKEPFQQQLKVFAEEVQQQAQLSTIRSFLKLYTTMPVAKLAGFLDMSEQE-----FRIQLLVFKHKMKNLVWTSGISALDGEFQSASEVDFYIDKDMIHIADTKVARRYGDFFIRQIHKFEELNRTLKKMPLNTGASISSSSTSRAT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VTU4-1", "uniprot_id": "EIF3L_DROME", "id": "Q9VTU4-1", "name": "Eukaryotic translation initiation factor 3 subunit L", "aln": "-MYGGDEYATNSDYY------DDYAHTGDPQLDMEYERNYY----AARMPDNVKYFLINFCQAIK--------------------EGNLYDIQNMYENTFPQISDHHFDKTAWPEEQEVAAIVDNDKVFLILYKELYYRHIHARIPGGPKLEQRINSFFNYCDFFNLIISAQNPVMLELPDIWLWELVDEFVYQFQNFAQYRARLTEKSQDEIQQLCVNHSNEWSILCILNVLHSLVDISNIKKQLEAISQGVDPQTVAGDFGKLSFYKMLGYFSLVGLLRVHSLLGDYYQAIKVLEPIEIHKKSAYSHIPACQISTSYYVGFAYMMMRRYADAIRTFSDILLYIQRTKQLYSTRSYQNDQINKQAEQMYHLLAICLVLHPQCIDESIQQVLREKNYHDAMFKMQCGDLEVFKSFFVFACPRFVSPCPPAVDAPMDDYVKDPMEHQLQVFMDEVRQQKDLPTTRSYLKLYTTLPLTKLASFIDPNASEDDVSKLLIRLLCFKHKMRNLVWSKGPSGLEGTFKSGSELDFYIDDDMIHIADTKVSHRYGDFFVRKILKFNDLNRKLKNINI---------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .: : * * *****: *: ***:* :*: :* *: * :::. : ::*:**::***:: :::::.*..:.*** : :*. *.** **************:*::.***.*:**::*::***::** *:.*:.*. ****: ***:::***:****.*:***.: ::**: *:: * * . *.: .:********* ***::***. :.* **::***::*: *:**************:*************** **::*** **::* **::* *******:***** ****.*::********:.::. :*: : **** ***: ****.*.::* *****: **** * * *::** ** :*::.:* ::**:*:** * : :* *:*: :**:** :**:** :*.* **:******:*::***.*:* . .* : *:** *****:****:.* *.*:* *:*.**:*****.**********::******:*:* **::***.**:: ", "identical_positions": 289, "similar_positions": 157, "identity": "49.4%" }, { "cls_id": "homologset.agr.RGD:1308231", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VEK2-1", "uniprot_id": "RHBD2_MOUSE", "id": "Q8VEK2-1", "name": "Rhomboid domain-containing protein 2", "aln": "---------------------------MAAPGPASRFWCSCPEVPSATFFTALLSLLVSGPRLFLLQPPLAP-SGLSLRSEALRNWQVYRLVTYIFVYENPVSLLCGAIIIWRFAGNFERTVGTVRHCFFTLIFTVFSAIIYLSFESVSSLSKLGEVEDARGFTPVAFAMLGVTSVRSRMRRALVFGVVVPSVLVPWLLLCAS-WLIPQTSFLSNVSGLLIG--LSYGLTYCYSLDLSERVALKLDQKFPFSLMRRIPL-FKYISGSSAERRAAQSRRLNPAPGSYPTQSCHPHLTPSYPVTQMQHASGQKLASWP---PGHMPSLPPYQPASGLCYVQNHFGPNPNASSVYPASAGTSQGVQPPSPISCPGTVYSGALGTPGATGSKESSKVAMP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZQG3-1", "uniprot_id": "D3ZQG3_RAT", "id": "D3ZQG3-1", "name": "Rhomboid domain-containing protein 2", "aln": "MGDRRKEAEIAEEGGECRGGTREGLAAMAASGPASRFWCSCPEVPSATFFTALLSLLVSGPRLFLLQPPLAP-SGLSLRSEALRNWQVYRLVTYIFVYENPISLLCGAIIIWRFAGNFERSVGTVRHCFFTLIFTVFSAIIYLSFESVSSLSKLGEVEDARGFTPVAFAMLGVTSVRSRMRRALVFGVVVPSVLVPWLLLCAS-WLIPQTSFLSNVSGLLIG--LSYGLTYCYSLDLSERVALKLDQKFPFSVMRRIPL-FKYISGSSAERRAAQSRRLNPPPGSYPTQGCHTHLTPSHPVTQMQHASGQKLASWP---PGHLPSLPPYQPASGLCYVQNHFGPNPNASSVYPASAGTSQGLQPPSPISCPGSVYSGVLGTPGATGSKESSKVAMP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6NTF9-1", "uniprot_id": "RHBD2_HUMAN", "id": "Q6NTF9-1", "name": "Rhomboid domain-containing protein 2", "aln": "---------------------------MAASGPGCRSWCLCPEVPSATFFTALLSLLVSGPRLFLLQQPLAP-SGLTLKSEALRNWQVYRLVTYIFVYENPISLLCGAIIIWRFAGNFERTVGTVRHCFFTVIFAIFSAIIFLSFEAVSSLSKLGEVEDARGFTPVAFAMLGVTTVRSRMRRALVFGMVVPSVLVPWLLLGAS-WLIPQTSFLSNVCGLSIG--LAYGLTYCYSIDLSERVALKLDQTFPFSLMRRISV-FKYVSGSSAERRAAQSRKLNPVPGSYPTQSCHPHLSPSHPVSQTQHASGQKLASWPSCTPGHMPTLPPYQPASGLCYVQNHFGPNPTSSSVYPASAGTSLGIQPPTPVNSPGTVYSGALGTPGAAGSKESSRVPMP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q12270-1", "uniprot_id": "RBD2_YEAST", "id": "Q12270-1", "name": "Rhomboid-type serine protease 2", "aln": "--------------------------------MNWKSYVFPGGHPPAALTTGLVVFLT---AIYLLSFIFALREDLSLAPESLFKLQMSRLSLYPLIHLSLPHLLFNVLAIWAPLNLFEETHGTVYTGVFLNLSALFAGILYCLLGKLLYPEALVAGASGWCFTLFAYYSFKESQIRPRTR-IFRTDYSIPTLYTPLVLLVAIAVVIPGSSFWGHFFGLCVGYAIGYKESWFNKITPPGWIITKIEKSLDG-LIRLIPWGIKYYRDEDIDR----------------TKDYEPLMSTETPLPLHNDNSGTVLGTA---------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : *.*:: *.*: :*. ::**. :* ..*:* .*:* : *: ** * ::: . ** ..: ** . **.: *** .* : ::*:.*:: : : . * .. ** .*: : : :*.* * : . :*:: .* :** * :** :** .:. ** :* :.* :: .: . : *:::.: ::* *. :** ... :* *:. .. ::.. *:. :. ** *.: ", "identical_positions": 59, "similar_positions": 97, "identity": "14.9%" }, { "cls_id": "homologset.agr.RGD:1308232", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q12458-1", "uniprot_id": "YPR1_YEAST", "id": "Q12458-1", "name": "Aldehyde reductase YPR1", "aln": "--MPATLKN-SSATLKLNTGASIPVLGFGTWRS----------------------------------------------VDNNGYHSVIAALKAGYRHIDAAAIYLNEEEVGRAIK----DSGVPREEIFITTKLWGTEQRDP--EAALNKSLKRLGLDYVDLYLMHWPVPLKTDRVTDGNVL--CIPTLEDGTVDIDTKEWNFIKTWELMQELPKTGKTKAVGVSNFSINNIKELLESPNNKVVPATNQIEIHPLLPQDELIAFCKEKGIVVEAYSPFG-----------SANAP-LLKEQAIIDMAKKH-GVEPAQLIISWSIQRGYVVLAKSVNPERIVSNFKIFT---LPEDDFKTISNLSK---VHGTKRVVDMKWGSFPIFQ--", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P14065-1", "uniprot_id": "GCY1_YEAST", "id": "P14065-1", "name": "Glycerol 2-dehydrogenase (NADP(+))", "aln": "--MPATLHD-STKILSLNTGAQIPQIGLGTWQS----------------------------------------------KENDAYKAVLTALKDGYRHIDTAAIYRNEDQVGQAIK----DSGVPREEIFVTTKLWCTQHHEP--EVALDQSLKRLGLDYVDLYLMHWPARLDPAYIKNEDIL--SVPTKKDGSRAVDITNWNFIKTWELMQELPKTGKTKAVGVSNFSINNLKDLLASQGNKLTPAANQVEIHPLLPQDELINFCKSKGIVVEAYSPLG-----------STDAP-LLKEPVILEIAKKN-NVQPGHVVISWHVQRGYVVLPKSVNPDRIKTNRKIFT---LSTEDFEAINNISK---EKGEKRVVHPNWSPFEVFK--", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q04828-1", "uniprot_id": "AK1C1_HUMAN", "id": "Q04828-1", "name": "Aldo-keto reductase family 1 member C1", "aln": "--MDSKYQ-----CVKLNDGHFMPVLGFGTYAP-------------------------------------------AEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVK----PGEE----VIPKDENGKILFDTVDL--CATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSH---REEPWVDPNSPVLLEDPVLCALAKKH-KRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQ-LTSEEMKAIDGLNRNVRYLTLDIFAG--PPNYPFSDEY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P52895-1", "uniprot_id": "AK1C2_HUMAN", "id": "P52895-1", "name": "Aldo-keto reductase family 1 member C2", "aln": "--MDSKYQ-----CVKLNDGHFMPVLGFGTYAP-------------------------------------------AEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVK----PGEE----VIPKDENGKILFDTVDL--CATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSH---REEPWVDPNSPVLLEDPVLCALAKKH-KRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQ-LTSEEMKAIDGLNRNVRYLTLDIFAG--PPNYPFSDEY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P42330-1", "uniprot_id": "AK1C3_HUMAN", "id": "P42330-1", "name": "Aldo-keto reductase family 1 member C3", "aln": "--MDSKHQ-----CVKLNDGHFMPVLGFGTYAP-------------------------------------------PEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLK----PGEE----LSPTDENGKVIFDIVDL--CTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQ---RDKRWVDPNSPVLLEDPVLCALAKKH-KRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQ-LTAEDMKAIDGLDRNLHYFNSDSFAS--HPNYPYSDEY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P17516-1", "uniprot_id": "AK1C4_HUMAN", "id": "P17516-1", "name": "Aldo-keto reductase family 1 member C4", "aln": "--MDPKYQ-----RVELNDGHFMPVLGFGTYAP-------------------------------------------PEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALK----PGET----PLPKDENGKVIFDTVDL--SATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQ---RHKLWVDPNSPVLLEDPVLCALAKKH-KQTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQ-LTSEDMKVLDGLNRNYRYVVMDFLMD--HPDYPFSDEY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VC28-1", "uniprot_id": "AK1CD_MOUSE", "id": "Q8VC28-1", "name": "Aldo-keto reductase family 1 member C13", "aln": "--MSSKQH-----CVKLNDGHLIPALGFGTYK-------------------------------------P------KEVPKSKSLEAACLALDVGYRHVDTAYAYQVEEEIGQAIQSKIKAGVVKREDLFITTKLWCTCFRPELVKPALEKSLKKLQLDYVDLYIMHYPVPMK----SGDN----DFPVNEQGKSLLDTVDF--CDTWERLEECKDAGLVKSIGVSNFNHRQLERILNKPGLKYKPVCNQVECHLYLNQRKLLDYCESKDIVLVAYGALGTQ---RYKEWVDQNSPVLLNDPVLCDVAKKN-KRSPALIALRYLIQRGIVPLAQSFKENEMRENLQVFGFQ-LSPEDMKTLDGLNKNFRYLPAEFLVD--HPEYPFVEEY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AD50-1", "uniprot_id": "A0A8I6AD50_RAT", "id": "A0A8I6AD50-1", "name": "", "aln": "--MAASCHYWAMALFKIQSSEYVNQISFGQAEYVAYLQRAEGRMSPLSEPEQAAGFLQVMRHCSCCLCSPGVSASYKLVPKSKSLEAAHLAIDAGYRHIDTAYAYQIEEEIGQAIQSKIKAGVVKREDMFITTKLWCTCFRPELVKPALEKSLKNLQLDYADLYIMHYPVPMK----SGDN----DFPVDEKGKSLLDTVDF--CDTWEMLEKCKDAGLVKSIGVSNFNHKQLERLLNKPGLKYKPVCNQVECHLYLNQSKLLDYCKSKDIVLVAYGALGTQ---RYKEWVDQNSPVLLNDPVLCDVAKKN-KRSPALIALRYLVQRGVVPLAQSFKENEMRENLQVFDFQ-LSPEDMKTLDGLNKNFRYLSAEFLAG--HPEYPFSEEY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VTY2-1", "uniprot_id": "Q9VTY2_DROME", "id": "Q9VTY2-1", "name": "NADP-dependent oxidoreductase domain-containing protein", "aln": "MKLAPT--------VKLNNGYEMPILGLGTYNS----------------------------------------------KDNEGEAAVKHAIDVGYRHIDTAYFYQNEAEVGKAIRDKIAEGVVKREDIFLVTKLWNIFHDPERVEGICRKQLSNFGLDYIDLYLMHMPVGYK----YVDDNT--LLPKNEDDVLQLSDVDY--LDTYKAMEKLVKLGLVRSIGVSNFNSEQLARVLAN--CEIKPVTNQVECSPALNQKALTAFCKKNDVTLTGYTPLGKP---KP----DIQKPDFIYSPEVAVIAKKY-GKTTPQIVLRYLVGLGVIPIPKSSNTNRISENFDIFDFE-LTAEEMAVLDGYHTGERVVPLNLIKGLNHKYYPFSIEF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38715-1", "uniprot_id": "GRE3_YEAST", "id": "P38715-1", "name": "NADPH-dependent aldose reductase GRE3", "aln": "--MSSLVT--------LNNGLKMPLVGLGCWKID----------------------------------------------KKVCANQIYEAIKLGYRLFDGACDYGNEKEVGEGIRKAISEGLVSRKDIFVVSKLWNNFHHPDHVKLALKKTLSDMGLDYLDLYYIHFPIAFKYVPFEEKYPPGFYTGADDEKKGHITEAHVPIIDTYRALEECVDEGLIKSIGVSNFQGSLIQDLLRG--CRIKPVALQIEHHPYLTQEHLVEFCKLHDIQVVAYSSFGPQSFIEMDLQLAKTTPTLFENDVIKKVSQNHPGSTTSQVLLRWATQRGIAVIPKSSKKERLLGNLEIEKKFTLTEQELKDISALNANIRFNDPWTWLDGKFPTFA-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . :: . : :.:* . *:. *:: .* * * * ::* .*: . * *:::* .:*** . *. *** *** :* * . .. . . *:. ::: . * :::*****. : :* . *. *:* : : * :*: :.: : .: .:* * :: . : :::: . : : : * :.:* : :.: * .: *. ::: :. : ", "identical_positions": 43, "similar_positions": 88, "identity": "11.03%" }, { "cls_id": "homologset.agr.RGD:1308233", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZWY4-1", "uniprot_id": "A0A8I5ZWY4_RAT", "id": "A0A8I5ZWY4-1", "name": "", "aln": "MPRDNMASLIQRIARQACLTFRGG-----------STGSEAP-APGFPENLSQLKSLLTQVRAEDLNIAPRKALPQPLPRN--LPPVTYMHIYETEGFSLGVFLLKSGTCIPLHDHPGMHGMLKVLYGKVRISCMDKLDTGAVHR--RPPPEQQFEPPLQPTEREAVRLGVLRSRAEYTEASGPCVLTPHRDNLHQIDAVDG-PAAFLDILAPPYDPED----GRDCHYYRVMEPIKPKEASGSACDLPREVWLLETPQ---ADDFWCEGEPYPGPKVLP-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PDY2-1", "uniprot_id": "AEDO_MOUSE", "id": "Q6PDY2-1", "name": "2-aminoethanethiol dioxygenase", "aln": "MPRDNMASLIQRIARQACLTFRGS-----------STGSEGP-APGFPENLSLLKSLLTQVRAEDLNIAPRKALPQPLPRN--LPPVTYMHIYETEGFSLGVFLLKSGTCIPLHDHPGMHGMLKVLYGTVRISCMDKLDTGAGHR--RPPPEQQFEPPLQPLEREAVRPGVLRSRAEYTEASGPCVLTPHRDNLHQIDAVDG-PAAFLDILAPPYDPED----GRDCHYYRVVEPIRPKEASGSACDLPREVWLLETPQ---ADDFWCEGEPYPGPKVLP-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96SZ5-1", "uniprot_id": "AEDO_HUMAN", "id": "Q96SZ5-1", "name": "2-aminoethanethiol dioxygenase", "aln": "MPRDNMASLIQRIARQACLTFRGSGGGRGASDRDAASGPEAPMQPGFPENLSKLKSLLTQLRAEDLNIAPRKATLQPLPPN--LPPVTYMHIYETDGFSLGVFLLKSGTSIPLHDHPGMHGMLKVLYGTVRISCMDKLDAGGGQRPRALPPEQQFEPPLQPREREAVRPGVLRSRAEYTEASGPCILTPHRDNLHQIDAVEG-PAAFLDILAPPYDPDD----GRDCHYYRVLEPVRPKEASSSACDLPREVWLLETPQ---ADDFWCEGEPYPGPKVFP-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB40E981-1", "uniprot_id": "A0AB40E981_DANRE", "id": "A0AB40E981-1", "name": "", "aln": "MPRDNMTSTVQKIAKQALATFRNP-----------SVIGEHN--KVFLENQSKLKSLLAEVRAADLKIAARTPESAPVPHQRIAPPVTYMHICETDSFSMGVFLLKTGASIPLHDHPGMYGMLKVIYGKVRISCFDRLDK---PR--DGASGVQFNPPLMPFQRGSLRPSVLKSVGEFTEDSSPCVLSPQQDNIHQIDAVDG-PTAFLDILAPPYDPDE----GRDCHYYKVLQAHSEAADKKSEVQDQGDVWLMEIPQ---PSEFWCGGEPYPGPKVTL-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VSD8-1", "uniprot_id": "Q9VSD8_DROME", "id": "Q9VSD8-1", "name": "2-aminoethanethiol dioxygenase", "aln": "-----MTTHFSNVLRQAFKTFDRAN------------------HASFNANLQHLRQLTDELTYRDLHLREELFRNVGSHRA----PCSYMHIFEDDRFSMSLFIVRGASTIPLHDHPMMFGLLRCIWGQLMVDSFS--------------HQLGPDEPLTYDPHQTVVKVNVEEPKLVTPASPCATLTPRKRNYHQIAQIGSGVAAFFDILSPPYDADMPTYGPRQCRFYRATAEGSQVQLHCIPSPDTYYCDVVDTPESVMQAAFQCADEVYADNASGTQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:: ...: :** ** * * . *:.* :: **:: . * :**** * : **:.:*::: .: ******* *.*:*: ::* : :..:. : ** : :: :.. * * . *:*:: * *** : . :**:***:****.: *:*::*:. ::: *: * * .* *.. ", "identical_positions": 58, "similar_positions": 66, "identity": "20.64%" }, { "cls_id": "homologset.agr.RGD:1308234", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q6ZPS2-1", "uniprot_id": "CRNS1_MOUSE", "id": "Q6ZPS2-1", "name": "Carnosine synthase 1", "aln": "----------------------------------------------------------------------------------------------------------------------------MLLCLSPAWLMKVATPGQEGEAVLLVSKAVSFYPGGLTFLDDFVPPRHATYFLAGLGPESGRGKEAAELARNLTCPTGTSSELSQLLENRLLMRWLLSQQSGVAVPATLAFTYRPPGLLRGGDASPGLRLVELSGKEGQETLVKEEVEAFVHSEALGDASQVAVRLSGCRWRGQQALPLHLRVEPSTVVNTVLGLLEKLEEEESVLVEAMCPPVRLPLPGGPAPGPELAVRICAVVCRIQGDRPLLSKVVCGVGRGDRPVRHHYTLPRTLRVALAQCGLEEEAQVALLEQGIKEAAEGALAAVLALEAGLSVEQRGGRQVHTDFLGVDLVLTVIGRTLTPVVLKLNSGLCLEACGALEGLWAVPRLRRSAEEAAAAPLVETMLRRSGRHLMDGKQLLVIGAGGVSKKFVWEAARDYGLTLHLVESDPNHFASQLVQTFIHFDVTEHRRDEENALLLAELVRARNLKLDGCFSFWDDCLVLTALLCRELGLPCSPPAAMCLAKQKSRTQLHLLRCQGPPWPSTSLHAVACCPLENEADVERAIYQVPLPGVMKLEFGSGAVGVQLVKDGPQCREHFSRILHDLQGEADHPGIGLGWGNAMLLMEFVEGTEHDVDLVVFGGRLLAAFVSDNGPTRLPGFTETAACMPTGLAPEQEAQVVQAAFRCCLGCGLLDGVFNVELKMTGAGPRLIEINPRMGGFYLRDWILELYGVDLLLASTMVACGLQPALPAHPRARGYLVGIMCLVSQHLQLLSSPSSRETLQTLHDQGQLRLNLLEEALIPGQYEEPYCNVACAGPSPAEACHRLLGICQGLGIDRPNYPVAHFLSHFK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0L9C0-1", "uniprot_id": "A0ABK0L9C0_RAT", "id": "A0ABK0L9C0-1", "name": "Carnosine synthase 1", "aln": "MLCLDPLGTEWDHPLGSKDLDGEEEPWKGGAGLPPTDCFPGPWRQDVSLDCKGSPEEAEARAWTVYYYGLLQSCLQQAGLPETQDRSQAPRTGCPGAEVTLCILGSPSTFLSLLLEGGVQSPGNMLLCLSPAWLMKVASAGQEGEADLLVSKAVSFYPGGLTFLDDFVPPRHATYFLAGLGPEFGHSKEAAELARHLTCPTGGSSELARLLEDRLLMRWLLSQQSGVAVPATLAFTYRPPGLLRGGDTSPGLRLVELSGKEGQETLVKEEVEAFVHSKALGDASQVAVRLSGWRWRGQQVLPLHLQEEPSTVVNTVLGLLEKLEEEESVLVEAMCPPVRLPLPGSPAPGPELAVRICAVVCRIQGDRPLLSKVVCGVGRGDQPVRHHYTLPRSLGVALAQCGLEEEAQVALLEQGIKEAAEAALAAVLALEAGLSVEQRGGRQVHTDFLGVDFVLTVVGRTLTPVVLKLNSGLCLETCGALEGLWAMPRLRRSAEEAAAAPLVETMLRRSGRHLMDGKQLLVIGAGGVSKKFVWEAAQDYGLKLHLVESDPNHFASQLVQTFIHFDVTEHRRDEENARLLAELVRARNLKLDGCFSFWDDCLVLTALLCRELGLPCSPPAAMCLAKQKSRTQLHLLRCQGPPWPSTSLHAVACCPLESEADVERAIYQVPLPGVMKLEFGSGAVGVQLVKDGPQCHEHFSRILHDLQGEADHPGIGLGWGNAMLLMEFVEGTEHDVDLVVFGGRLLAAFVSDNGPTRLPGFTETAACMPTGLAPEQEAQMVQAAFRCCLGCGLLDGVFNVELKMTGAGPRLIEINPRMGGFYLRDWILELYGVDLLLASAMVACGLQPALPAHPRARGYLVGIMCLVSQHLQLLSSPGSRETLQALHDQGQLRLNLLEEALIPGQYEEPYCNVACAGASPAEARHRLLGICQGLGIDRPNYPVAHFLSHFK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A5YM72-1", "uniprot_id": "CRNS1_HUMAN", "id": "A5YM72-1", "name": "Carnosine synthase 1", "aln": "----------------------------------------------------------------------------------------------------------------------------MLLCLSPAWLMKVPAPGQPGEAALLVSKAVSFHPGGLTFLDDFVPPRRATYFLAGLGLGPGRGREAAELARDLTCPTGASAELARLLEDRLLTRQLLAQQGGVAVPATLAFTYKPPGLLRGGDASLGLRLVELSGKEGQETLVKEEVEAFLRSEALGDILQVAVKLSGWRWRGRQAWRLHPRAELGAVVDTVLALLEKLEEEESVLVEAVYPPAQLPCSDGPSPGPGLAVRICAVVCRTQGDRPLLSKVVCGVGRGDRPLRHHNSLPRTLEVALAQCGLGEEAQVAAVRQRVKAAAEAALAAVLALEAGLSAEQRGGRRAHTDFLGVDFALTAAGGVLTPVALELNGGLCLEACGALEGLWAAPRLGPAADEAVAAPLVETMLRRSARCLMEGKQLLVVGAGGVSKKFVWEAARDYGLQLHLVESDPNHFASQLVQTFIHFDMTEHRRDEENARLLAELVRARGLKLDGCFSYWDDCLVLTALLCQELGLPCSSPAAMRLAKQKSLTQLHLLHHHGPPWPAPSLHAVPCCPLESEADVERAVHQVPLPGVMKLEFGAGAVGVRLVEDAPQCHEHFSRITRDLQGEADHPGIGLGWGNAMLLMEFVEGTEHDVDLVLFGGRLLAAFVSDNGPTRLPGFTETAACMPTGLAPEQEAQMVQAAFRCCLGCGLLDGVFNVELKLTGAGPRLIEINPRMGGFYLRDWILELYGVDLLLAAVMVACGLRPALPTRPRARGHLVGVMCLVSQHLQALSSTASRETLQALHDRGLLRLNLLEEALVPGEYEEPYCSVACAGPSPTEARLRLLGLCQGLGIDGPSYPVAHFLSHFK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *************.:.** *** *********:**************:********* *:.:*******.****** *:**::***:*** * **:**.************:*********:* ************************::*:**** ****:*** ****:*. ** : * .:**:***.***************: **.:** ...*:*** *********** ******************:*:*** :***:* ******** ****** :.* :* ***.*************.******:.********:.**. * .****.*:**.*****:********* *** :*:**.************.* **:******:**************:**** ***********************:********** *********.********:************:*******.**** ****** ******: :*****:.*****.*****.*******::*************:*****:**:*.***:****** :***********************************:***************************************:***********************:**********************************:.******:****::*****:***:********* ***..******:***:* **********:**:******.*****.**:** ****:******* *.***********", "identical_positions": 682, "similar_positions": 101, "identity": "71.71%" }, { "cls_id": "homologset.agr.RGD:1308236", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5FVQ0-1", "uniprot_id": "S39A8_RAT", "id": "Q5FVQ0-1", "name": "Metal cation symporter ZIP8", "aln": "MAPGRAVAGLLLLAATGLGRPSEGPELAFTEDVLRVFGANQSLSAAQLGRLLERLGAAPQQGALELGQ-LHFNQCLSAEDIFSLHGFSNVTQITSSNFTAICPAILQQLNFHPCEDPQK---HSVKPSFSEVWGYGFLSVTIINLASLLGLILTPLIKKSYFPKILTYFVGLAIGTLFSNAIFQLIPEAFGFNPKIDNYVEKAVAVFGGFYMLFFVERTLKMLLKTYGQNDHTHFRNDDFGSKEKAHQPKTLPLPPVNG--VTCYANPAVTEPNGHIHFDTVSVVSLQDGKAESSSCTCLKGPKLSEIGTIAWMITLCDALHNFIDGLAIGASYTLSLLQGLSTSIAILCEEFPHELGDFVILLNAGMSTRQALLFNFLSACSCYVGLAFGILVGNNFAPNIIFALAGGMFLYISLADMFPEMNDMLREKVTGRQTDFTFFMIQNAGMLTGFTAILLITLYAGDIELQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91W10-1", "uniprot_id": "S39A8_MOUSE", "id": "Q91W10-1", "name": "Metal cation symporter ZIP8", "aln": "MAPGRAVAGLLLLAATSLGHPSEGPELAFSEDVLSVFGANRSLSAAQLGRLLERLGAASQQGALDLGQ-LHFNQCLSAEDIFSLHGFSNVTQITSSNFSAICPAILQQLNFHPCEDLRK---HNAKPSLSEVWGYGFLSVTIINLASLLGLILTPLIKKSYFPKILTYFVGLAIGTLFSNAIFQLIPEAFGFNPKIDNYVEKAVAVFGGFYMLFFVERTLKMLLKTYGQNDHTHFRNDDFGSKEKTHQPKTLPLPAVNG--VTCYANPAVTEPNGHIHFDTVSVVSLQDGKTEPSSCTCLKGPKLSEIGTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVILLNAGMSTRQALLFNFLSACSCYVGLAFGILVGNNFAPNIIFALAGGMFLYISLADMFPEMNDMLREKVTGRQTDFTFFMIQNAGMLTGFTAILLITLYAGDIELQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9C0K1-1", "uniprot_id": "S39A8_HUMAN", "id": "Q9C0K1-1", "name": "Metal cation symporter ZIP8", "aln": "MAPGRAVAGLLLLAAAGLGGVAEGPGLAFSEDVLSVFGANLSLSAAQLQHLLEQMGAASRVGVPEPGQ-LHFNQCLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPCEDRPK---HKTRPSHSEVWGYGFLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQLIPEAFGFDPKVDSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQNGHTHFGNDNFGPQEKTHQPK--ALPAING--VTCYANPAVTEANGHIHFDNVSVVSLQDGKKEPSSCTCLKGPKLSEIGTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVILLNAGMSTRQALLFNFLSACSCYVGLAFGILVGNNFAPNIIFALAGGMFLYISLADMFPEMNDMLREKVTGRKTDFTFFMIQNAGMLTGFTAILLITLYAGEIELE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AYZ5-1", "uniprot_id": "A0A8M3AYZ5_DANRE", "id": "A0A8M3AYZ5-1", "name": "", "aln": "------------------------MEESFLQNVLGFYGEESSLSVGNLELFLQLITSRRAAAVEDEGNPLKSAECLSLSELLSAFGLSNASVVSVSNLEMMCPAILNQVLIPACPYTSSNLNASASISDHKVWGYGFLAVTVINLAALLGLFLVPFTKKKYFPKVLMYFIGLAIGTLFSNAVLQLIPEALGLDPKDDNYVLNVVGIFGGFYILFVTERILKMVLKTDTELGHSHFPPLQSSDVTISTISNDVVISNISGDIITNNTNHEQNSISEKSNNPSESPAVEQN-ACALFACRWLKGSAMSNIKTVAWMITVSDALHNFIDGLAIGASFTLSLLSGFSTSIAIFCEEFPHELGDFVILLNSGMSVGQAAFFNLLSAMCCYLGLALGILLGSNFAPNAIFAIAGGMFLYISLADMFPEMNSIMASHTKDYQERVVFFLIQNAGLLTGFTIILLITLFAGDINLQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* ::** .:* : ***..:* :*: : : .. : *: *: :**: .:::* .*:**.: :: *:: :***:*:*: : .* . .. * :*******:**:****:****:*.*: **.****:* :*:***********::******:*::** *.** :.*.:*****:**. ** ***:*** : .*:** : . : .: :. :.* :* :* .. . : : . * . *: :* ***. :*:* *:*****:.*************** *****.*:******:****************:***. ** :**:*** .**:***:***:*.***** ***:******************.:: .:... : ..**:*****:***** ******:**:*:*:", "identical_positions": 221, "similar_positions": 124, "identity": "47.22%" }, { "cls_id": "homologset.agr.RGD:1308239", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VPS1-1", "uniprot_id": "Q9VPS1_DROME", "id": "Q9VPS1-1", "name": "", "aln": "------MFKYDTYFLYLIVLLDPQGAQENNCPKVSLSERLEKRGEFSLVEFDPLLKFIVK-----------------------------------------NPHKELLGEIEGLVGHTENKLQPMKSVIPNQSKALLNYLD----LHSKLEYLDAAL-----------------------------------------------------------------------------------------------------------------------------------------------------------------QKAINSLQCSLKNTKVMSTGKPHPEFQKLGSRYFYIERHVRQNWFDAADKCRRMGGHLATPQDEDELYLIRKQLEAR------WFWLDISNL-----------------------------VDKDQYISLATG-KEVSYLK--WRHGEPKKSSTANCAYLYAG-------DYYTYQCSDR----NFFICQAV------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VPS2-1", "uniprot_id": "Q9VPS2_DROME", "id": "Q9VPS2-1", "name": "", "aln": "------MFQHANFFLHVFMACGLYGIRAK-----DVCPRMSTDKEVCLVELAPVLKYISNNHK---------------------------SHWNSANEVQVNETRKQLAKIEGQEKETNDKIKVIHDNVDNEFNALSAKIKNVKNIQRHLASLELQL-----------------------------------------------------------------------------------------------------------------------------------------------------------------QETKKALNLSVEAKKVMPKTEIPSQFQKIGWRHFFIEKKHKVDWFKATSMCHKMGAHLLTIQSEDELDAIRTELKDINDG-SHDFWLDINDI-----------------------------AKWGEFISLATG-MNPPFLK--WHKHRPQVQIHQRCVHLRGG-------EMMDGKCSEQ----FLFICQLAVN----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "D3ZP17-1", "uniprot_id": "D3ZP17_RAT", "id": "D3ZP17-1", "name": "", "aln": "---------------------------------------MSESKETGKQQLGPLDEELLTS-----------------------------SHTRYSMKGFGFQPNSGFSSFTGYLVHSHVPLALKALFLTVFSVLLVVILVKVYKIPSSHEQEESNQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------KNFYQELIQLKAGVDRLCRSCPWDWTAFQGNCYFFSV--AQKSWNDSATACHNVGAQLVVIKSEEEQNFLQKTSKKRG-----YTWMGLIDI-----------------------------NKESTWHWVDGSPLTLTFMKY-WNKGEPNNVGDKDCAEFRED-------GWNDTKCDNK----KFWICKKPETSCSSK-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91ZX1-1", "uniprot_id": "C209A_MOUSE", "id": "Q91ZX1-1", "name": "CD209 antigen-like protein A", "aln": "---------------------------------------MSDSKEMGKRQLRPLDEELLTS-----------------------------SHTRHSIKGFGFQTNSGFSSFTGCLVHSQVPLALQVLFLAVCSVLLVVILVKVYKIPSS--QEENNQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------MNVYQELTQLKAGVDRLCRSCPWDWTHFQGSCYFFSV--AQKSWNDSATACHNVGAQLVVIKSDEEQNFLQQTSKKRG-----YTWMGLIDM-----------------------------SKESTWYWVDGSPLTLSFMKY-WSKGEPNNLGEEDCAEFRDD-------GWNDTKCTNK----KFWICKKLSTSCPSK-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NNX6-1", "uniprot_id": "CD209_HUMAN", "id": "Q9NNX6-1", "name": "CD209 antigen", "aln": "---------------------------------------MSDSKEPRLQQLGLLEEEQLR--------------------------------------GLGFRQTRGYKSLAGCLGHG--PLVLQLLSFT----LLAGLLVQVSKVPSSISQEQSRQDAIYQNLTQLKAAVGELSEKSKLQEIYQELTQLKAAVGELPEKSKLQEIYQELTRLKAAVGELPEKSKLQEIYQELTWLKAAVGELPEKSKMQEIYQELTRLKAAVGELPEKSKQQEIYQELTRLKAAVGELPEKSKQQEIYQELTRLKAAVGELPEKSKQQEIYQELTQLKAAVERLCHPCPWEWTFFQGNCYFMSN--SQRNWHDSITACKEVGAQLVVIKSAEEQNFLQLQSSRSNR----FTWMGLSDL-----------------------------NQEGTWQWVDGSPLLPSFKQY-WNRGEPNNVGEEDCAEFSGN-------GWNDDKCNLA----KFWICKKSAASCSRDEEQFLSPAPATPNPPPA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VLM0-1", "uniprot_id": "Q9VLM0_DROME", "id": "Q9VLM0-1", "name": "", "aln": "------MYKYATCIFSIFALWNFWGVSAK---------KQDTSTGTNELPKAPMPYYTIEN--------------------------------------IDMHQQHWFTYNSLRQNGTLWRIGNMEQRLEMRLQSFQNQMETKL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RALKQQIEPYMENVK-MSNKIKMSVFKKIGSRHFYLEKQKKMPWDSAYDTCRQMGGHLANILDEKELNEIFSEETKKK------YWVDINSR-----------------------------ANDGASWISTLSGRDVPFLK--WKPNLATN-IHNHCVYINSN-------EMYFENCAND----NYFACQAEQWA---------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0AB32TFP3-1", "uniprot_id": "A0AB32TFP3_DANRE", "id": "A0AB32TFP3-1", "name": "", "aln": "-----MTSGIEMAQPIYGNILVNYDPTPKMDRCSLRNETASDSGKKRSSRAAPVCLVLLCLLL---------------------------LTAVIVLSVFIYTNNTNFAEERRQLITNIANITEDRDKLLTDIINLTKIKDKVLINITNLEEDRDELLN------------------------------------------------------------------------------------------------------------------------------------------------------KITTFTKARNEILKKNANLLKDKDQLIKQLQVFGQEAYYQSSFYYLSSERKSWTESRRDCKDRGADLIIINNKQEQDFIMKITSNNE------FWIGLTDS-----------------------------DKEGIWKWVDGSNLTSRFWASSGSITEPNGRKTENCAVTHLKKH-PELIGWLDVACDGA----YQWICEKNILPVTS------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VIX1-1", "uniprot_id": "Q9VIX1_DROME", "id": "Q9VIX1-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------MLKLTVLLITLLVIAKTG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WTREKFSIQVNEGNTFGALVKAEPFTKINDGYYFFG-TESLNWYEAYEKCRELNSELVTFETDQEFDAVTAFLTANGS--RLTYWTSGNDL-----------------------------AKTGSHRWFTNAQRISSLRWA--RNQPDNAGQKEHCIHLGYIYKDSRKFELNDRPCSQDPNSLFKYICEAPEMETISIVVWK-------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "B7Z0K3-1", "uniprot_id": "B7Z0K3_DROME", "id": "B7Z0K3-1", "name": "C-type lectin domain-containing protein", "aln": "MPPAGQQLRLTALVYLALGIALLCNGSDGETRQKYANESLADADDPSPVWSQFLEDYVLSQGSSSSGSQRKSKDLPYMGADMGINGPLSYHSSAYKRPGNNIYITRRIGEAVELEPHLRKPVESQSPIVNPQFRPMTNQMLHQQHQQMQQQQQQQQLQQRQQPGFLQQLFG---------------------------------------------------------------------IGGSGGGGGSGTQQQQHVRPVPLQQQQVQQIAQQHPQQQHLVGGQPTTFRAVSENDLYLLGAIEKLVYRVDYLESRVRRSEQLIYYLMAGNNQKEVKDPCPANFTRISDNCYYINSQQQVNWKTANSACKGLNSHLAEFEKVSENEEIMAYLLNQPTHRGRDYWLGGLNPGLLWIWSNSAKPVNPNMNLTSIAMAQKGENSTAANLVDSSEQAAEEATGEDVLNNTVQIEGKGRCLRLSYNAG-KHSYVYYGQECTSR----HYYICEHEDKTLDNKIKKITRELKLFE-----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . : * : *: ...* .* : * . . . * * : *: ", "identical_positions": 8, "similar_positions": 16, "identity": "1.5%" }, { "cls_id": "homologset.agr.RGD:1308240", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4AD36-1", "uniprot_id": "D4AD36_RAT", "id": "D4AD36-1", "name": "F-BAR and double SH3 domains protein 1", "aln": "MQPPPRKVKPAQEVKLRFLEQLSILQTRQQREADLLEDIRSYSKQRAAIEREYGQALQKLAGPFLKREGQRSGEVDSR----ARTVFGAWRCLLDATVAGGQTRLQASDRYRDLAGGTG---RSAKEQVLRKGTESLQQAQAEVLQSVRELSRSRKLYGQRERVWALAQEKAADVQARLNRNDHGIFHSRTSLQKLSTKLSAQSAQYSQQLRAARNEYLLNLVATNAHLAHYYQEELPALLKVLVSELSEYLRDPLTLLGHTELEAAEMILEHARHGGKAASQVNWEQDVKLFLQGPGVFSPTPPQQFQPAGTDQVHALERGAGGMAEESGLEREVQRWTSRAARDYKIQHHGHRVLQRLELRRQQAPERE-----APGVEQRIQEVRENIRRAQVSQVKGAARLALLQEAGLDVQRWLKPAMTQAQDEVE----------------------------QERRLSEARLSQRDLSPTAEDAELSDFDECEEAGELFEEPAPPALATRALPCP------------------------------------AHVVFGYQAGREDELTITEGEWLEVIEEGDADEWVKARNQHGEAGFVPERYLNFPDLSLPESSHGSDN--------------------------------------PSGAEPTAFLARALYSYIGQSEEELSFPEGALIRLLPRAQDGVDDGFWRGEFGGHVGVFPSLLVEELLGPPGPPELSDPEQMLPSPSPPSFSPPAPTCALD-----------------------------RSPAPALPSDKVIDCPGPLDMMVPRLRPMRPPPPPPAKAPDPGHPDPLT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PFY1-1", "uniprot_id": "FCSD1_MOUSE", "id": "Q6PFY1-1", "name": "F-BAR and double SH3 domains protein 1", "aln": "MQPPPRKVKPAQEVKLRFLEQLSILQTRQQREADLLEDIRSYSKQRAAIEREYGQALQKLAGPFLKREGQRSGEADS------RTVFGAWRCLLDATVAGGQTRLQASDRYRDLAGGTG---RSAKEQVLRKGTESLQQAQAEVLQSVRELSRSRKLYGQRQRVWALAQEKAADVQARLNRSDHGIFHSRTSLQKLSTKLSAQSAQYSQQLRAARNEYLLNLVATNAHLAHYYQEELPALLKVLVSELSEYLRDPLTLLGHTELEAAEMILEHARHGGKATSQVNWEQDVKLFLQGPGVFSPTPPQQFQPAGADQVCGLEWGAGGMAGESGLEKEVQRWTSRAARDYKIQHHGHRVLQRLEQRRQQAPGRE-----APGVEQRLQEVRENIRRAQVSQVKGAARLALLQEAGLDVQRWLKPAMTQAQDEVE----------------------------QERRLSEARLSQRDLSPTAEDAELSDFDECEEAGELFEEPAPPALATRPLPCP------------------------------------AHVVFGYQAGREDELTITEGEWLEVIEEGDADEWVKARNQHGEAGFVPERYLNFPDLSLPESCHGIDN--------------------------------------PSGGEPTAFLARALYSYTGQSEEELSFPEGALIRLLPRAQDGVDDGFWRGEFGGHVGVFPSLLVEELLGPPGPPELSDPEQMLPSPSPPSFSPPAPTCALD-----------------------------GSTAPALPSDKVLDCPGPLDMMVPRLRPMRPPPPPPAKAPDPGHPDPLT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86WN1-1", "uniprot_id": "FCSD1_HUMAN", "id": "Q86WN1-1", "name": "F-BAR and double SH3 domains protein 1", "aln": "MQPPPRKVKPAQEVKLRFLEQLSILQTWQQREADLLEDIRSYSKQRAAIEREYGQALQKLAGPFLKREGHRSGEMDSR----GRTVFGAWRCLLDATVAGGQTRLQASDRYRDLAGGTG---RSAKEQVLRKGTENLQRAQAEVLQSVRELSRSRKLYGQRERVWALAQEKAADVQARLNRSDHGIFHSRTSLQKLSTKLSAQSAQYSQQLQAARNEYLLNLVATNAHLDHYYQEELPALLKALVSELSEHLRDPLTSLSHTELEAAEVILEHAHRGEQTTSQVSWEQDLKLFLQEPGVFSPTPPQQFQPAGTDQVCVLEWGAEGVAGKSGLEKEVQRLTSRAARDYKIQNHGHRVLQRLEQRRQQASERE-----APSIEQRLQEVRESIRRAQVSQVKGAARLALLQGAGLDVERWLKPAMTQAQDEVE----------------------------QERRLSEARLSQRDLSPTAEDAELSDFEECEETGELFEEPAPQALATRALPCP------------------------------------AHVVFRYQAGREDELTITEGEWLEVIEEGDADEWVKARNQHGEVGFVPERYLNFPDLSLPESSQDSDN--------------------------------------PCGAEPTAFLAQALYSYTGQSAEELSFPEGALIRLLPRAQDGVDDGFWRGEFGGRVGVFPSLLVEELLGPPGPPELSDPEQMLPSPSPPSFSPPAPTSVLD-----------------------------GPPAPVLPGDKALDFPGFLDMMAPRLRPMRPPPPPPAKAPDPGHPDPLT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "X2JAU8-1", "uniprot_id": "NWK_DROME", "id": "X2JAU8-1", "name": "Protein nervous wreck", "aln": "MQPPPRKGNYVKFLKNLHTEQVAKLQLKNQHECDLLEDIRQFTIKRSAVEKSYSESLLKISSQYLNKKIPNIPDIKMEGMEERWNMWSVWRTVLEENEKLARARLAAIEVFQQQIADEAKVLRDYKLAIAKRSLAGIVNVQKELHLSVGDVDKTKKSYFDEEHCAHDVRDKARDIEEKLKKKKGSFFQSITSLQKNSARVTSRKELLEEKSSGARNDYVLSLAAANAHQNRYFTVDLQTTMTTMENYVFERVAEYLMLMGRTELLTCSATQNSFGKIRDQAQQLTREYNLQCCYLFYPVLKQHIQYDFEACDNDPVRKVTAEHESAAET--LTKEAKNLAGRVVKENASIRENAKKLALCQSLRDSGQRTDPNDPNGPDLDTKIEEFRDQIRRSETEKTKAEACLQCLRDGGINVDEWVQEAENMGVQELTRSASSISMRTDASGQGENPSSDSFYDSDKEETQAAAQTKPKQEQQLSRDRTFSDSEDEPEVRPSAAAASSAAAASSSMMASSAGGWDDPTEVNWGAGEEEDDKDEPIVPEPKEAIFKCTALYSYTAQNPDELTIVENEQLEVVGEGDGDGWLRARNYRGEEGYVPHNYLDIDQETAGSAFNGTSGNQLRSQISFSSVDYTVDNEDQTVDSMQSPDQVSVIMAPQKRVKSDVEWCIALYDYDATAEDELTFEEGDKIKIITKTAHGVDDGWWEGELDGKFGNFPSLVVEECDEMGEPLSEGGDESPPPTAAPTFALPPAPALPPEYAHELELELTEDMFGSQDTADEDSGYIPNGAAAPSIPPPVLIQEPGMEDDLSDDGQPPPSLPPPQLAKAGGSAPGSGSKVEKGAAAGGANTLNLGMAQIIVTAATPMVEDGADKSFPPVGESDAQPVEPVSKEQPAEVAKKPDIAPKPLAKVAPQSAPAKEGNAGVRPVVSITLTEYPSCDAEDQQSFSEGTDSASVADVPVLQDAEDPFNEKAKGESGDGSGFEANFEANFDANFDDAFAGIGGGGGGGGGGGEQSNELDINGEAAGEAIVSGSAAGDEDIEAPKQVVGGRASIPEELDSNQLAHYHEHEIYYVDYSHGQL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******* : .: :* . **:: ** :*:*.*******.:: :*:*:*:.*.::* *::. :*::: . : . .::..** :*: . .::** * : ::: .. . *. * : ::. .: ..* *: ** ::.:::* * :.:: .::** *:: :*::.. .:*:* ***** *::::::. .:: .***:*:*.*.*:*** :*: :* : :..: . : * : : * :.:*** :.. : : . :.*:. * ::: *:. :*:... * * : . * * :*.:. :.*..:: ... : * : *:.. : .*.:: :::*.*:.***::..:.*. * * *: .*::*:.*:: * . . :*: :*. : *: . :: . :.* :** :: *. .:. * *: .: .. . .:: * * . *****.*.* ***: ***.* *::*** :** *:**..**:: : : .: :. .. :. . . ***.* . : :**:* ** *:::.:: .*****:*.**:.*:.* ****:*** * . .. *. *:.:*. ****: : ..** :* :: ** * : :* . *** .. . *.. : ", "identical_positions": 179, "similar_positions": 277, "identity": "16.62%" }, { "cls_id": "homologset.agr.RGD:1308241", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K4I3-1", "uniprot_id": "A0A0G2K4I3_RAT", "id": "A0A0G2K4I3-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTQWDLKTVLSLPQYPGEFLHP-----------VVYACTAVMLLCLLASVITYILHQSAIRISRKGRHALLNFCFHAALTFTVFAGGINRTKHPILCQAVGIALHYSTLSTMLWIGVTARNIYKQVTKKALPCPG-----ADQP--PYPKQPLLRFYLISGGVPFIICGVTAATNIRNYGTEDEDVAYCWMAWEPSLGAFYGPAAFITLVTCVYFLCTYVQLRRHPERRYELRERTEEQQRLAVPETGHRHGMRP-----GTPPTCDALAASQLQN---------------------------EHSFKAQLRAAAFTLFLFTATWTFGALAVSQGDFLDMIFSCLYGAFCVTLGLFVLIHHCAKREDVWQCWWS-----CCPSRGDTSAT---KPSAHPTLDANGDALGH----TACLQDSPCPGKLRGFGHPPASHCKMTNLHAAQGHVSCLS----------------------------------------------PATPCCAKMHCEQ-LMEEEA-HVHMGEEDAFPHDHH----------------------------LHDPHLHRCLKGRTKPHYFSRHQAAAAEREYAYHIPS-SLDGSPHSSRTESPTSS--------------------------------------------------------------------------------------------LEGPMGVHTLACCAQADPF---------PMVS--QPEGGDTSPGLYG----------------------------------------------------------------------------------CPPR----LSPGPAHLEMLR-RTQSLPFGSP---SQNGLL--QGDVREGLPFGTDGTGNIRTGPWKNETTV-----------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C4G9-1", "uniprot_id": "AGRA1_MOUSE", "id": "Q8C4G9-1", "name": "Adhesion G protein-coupled receptor A1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTQWDLKTVLSLPQYPGEFLHP-----------VVYACTAVMLLCLLASVITYILHQSAIRISRKGRHALLNFCFHAALTFTVFAGGINRTQHPILCQAVGIALHYSTLSTMLWIGVTARNIYKQVTKKALPCPG-----ADQP--PYPKQPLLRFYLISGGVPFIICGVTAATNIRNYGTEDEDVAYCWMAWEPSLGAFYGPAAFIALVTCVYFLCTYVQLRRHPERRYELRERTEEQQRLAVPESGHRHGVRP-----GTPPTCDALAASQLQN---------------------------EHSFKAQLRAAAFTLFLFTATWTFGALAVSQGHFLDMIFSCLYGAFCVTLGLFVLIHHCAKREDVWQCWWS-----CCPSRGDTSTT---KPGAHPTLDANGDALGH----TACLQDSPCPGKLRGFGHPPASHCKMTNLQAAQGHVSCLS----------------------------------------------PATPCCAKMHCEQ-LMEEEAAHIHMAEEDVYPHDPH----------------------------LHDPHLHRCLKGRTKSHYFSRHQAAAAEREYAYHIPS-SLDGSPHSSRSESPTSS--------------------------------------------------------------------------------------------LEGPMGMHTLACCAQADPF---------PMVS--QPEGGDTSPGLYG----------------------------------------------------------------------------------CPPH----LSPGPAHLEMLR-RTQSLPFGGP---SQNGLL--QGDVREGLPFGTDGTGNIRTGPWKNETTV-----------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86SQ6-3", "uniprot_id": "AGRA1_HUMAN", "id": "Q86SQ6-3", "name": "Adhesion G protein-coupled receptor A1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDLKTVLSLPRYPGEFLHP-----------VVYACTAVMLLCLLASFVTYIVHQSAIRISRKGRHTLLNFCFHAALTFTVFAGGINRTKYPILCQAVGIVLHYSTLSTMLWIGVTARNIYKQVTKKAPLCLD-----TDQP--PYPRQPLLRFYLVSGGVPFIICGVTAATNIRNYGTEDEDTAYCWMAWEPSLGAFYGPAAIITLVTCVYFLGTYVQLRRHPGRRYELRTQPEEQRRLATPEGGR--GIRP-----GTPPAHDAPGASVLQN---------------------------EHSFQAQLRAAAFTLFLFTATWAFGALAVSQGHFLDMVFSCLYGAFCVTLGLFVLIHHCAKREDVWQCWWA-----CCPPRKD----------AHPALDANGAALGR----AACLH-SPGLGQPRGFAHPPG-PCKMTNLQAAQGHASCLS----------------------------------------------PATPCCAKMHCEP-LTADEA-HVHLQEEGAFG---------------------------------HDPHLHGCLQGRTKPPYFSRHPAE--EPEYAYHIPS-SLDGSPRSSRTDSPPSS--------------------------------------------------------------------------------------------LDGPAGTHTLACCTQGDPF---------PMVT--QPEGSDGSPALYS----------------------------------------------------------------------------------CPTQPGREAALGPGHLEMLR-RTQSLPFGGP---SQNGLP--KGKLLEGLPFGTDGTGNIRTGPWKNETTV-----------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GY35-1", "uniprot_id": "A0AC58GY35_DANRE", "id": "A0AC58GY35-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRRKHRLEHKEPDLKRVLSFPPYPGDYLHP-----------VVYACTAVMLLCLLISIMTYIVHHSIIRISRKGWHMLLNFLFHTAMTFGVFAGGINQIKYPVICQVVGIILHYSSLSSMLWLLFTARNVCKEVSKAPPIPQD-----RDPPTQPRPKATIFRFYLVSGGVPLIIVGVTAAVNLDNYGSRD-DAPYCWMAWEPSLGGFYGPTAFLVLVMCIYFLCTYVQLKRHPERKYELKAMTEEQQRLAVAEIGHCHAVSGEPGEHGDHTGCTAITASMLAN---------------------------EHSFKAQLRATAFTLFLFLATWVFGALAVSQGHFLDMIFSCLYGAFSVTLGLFLLIQHCAKRDDVWHRWWA-----CCPNKPKVEVNGEAAGNAIPTTQSHSHTPSHGQNQIHCQVDSSCLGKPLLSPHLSP-HCKLGSLPSTQNHTS----------------------------------------------------TCCATLHSPSSLIGSSTRPQSLPDELPRP----------------------------------TLPLQSCLKDRSKTRSFNRPRPC--LRDYSYHMTSTSMDGSVHSSHLDSPHSVH-------------------------------------LDNPLTCHTSHLDTQLSCHSPHPDNQLRCPSPSPHLETLASHGLHDSLSCHSAHLDSQLSCHRHMCCAKADPFSSICCPNADPFVSPCQAEDPDMGSLMYS----------------------------------------------------------------------------------CAKMADK-EDESMLHLDITPPRVSHATLGRKGTLSRRGTLSRNSSQHEDYAITSDSTGNIRTGPWKNETTV-----------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KV24-1", "uniprot_id": "Q7KV24_DROME", "id": "Q7KV24-1", "name": "", "aln": "MPTATATSTAAEGGQAVQVQTHQDTELPQNPETGIATGQGTASSCPRKCSCRSTAENIHSLKIRCDEQQITNWRELDFGEDVTSIVSINASKNSIALITAEDFRNFTELKRLDLSFNLLTELDKDTFGDSLAHLEKLKLAGNAISHIYEGTFDQMPKLKLLDLSGNPLACDCGLIWLIAWSSSREVRLQPPPKCESPGNFRGMPLKKLRVGKDFHCETLLQPLLELIPSQNQVAFEGDELQLKCHAPRVAIGVPRESEDLPTKAYVFWGWSEKIRAKNSTEDIIYQDPTKVFGDVNLETRHSTDSGILQSILRIASLTQNHTGMWDCTLRSQQANLSQAIVLHVVAKGTLYCEARVVHTNKGTYHWPRTMRGETVLQECVEEPSDATQARRASHECGPSGEWLNLDTESCVYVSETTRILEQFAKVNLTLTKGQNALEIARRLHNFTQAQTQLNRIRDPMDLEYIARTLVKYLDQLEQPQQQQEISHLLMDIVSQLLNLPAHLFRAAQSEQGTGQRLLHVVESSAMRLALASTQAEPLPAEMIPWRGSLAQQRNLFVEFFNISLDAFVSLSCVWLEQSPRGFQCNSANDTIPMYEHGDIDAAIQLPYSVIGNSSTTLPATTTIRSLRLMISLHRNGKLLPNLRGSHNESLSSAIIGILAYSSDGEALQFRADNELDPEEDVYQQRVTVMLRAHPYHNPLSAPQPAWWDADEQRWETSVCQQHYQHRTLVMFSCSRTGYYGLLQRSQYLNDFRSEESGARFRHPPAAVYAGCGLLFACCAFNAVTFAVFGRAVRINRVQRHALVNTWLALGALALAFSLGIYQTASQPQCRLLGLLMHYLGLCVLLWVCVSLSSMYKRLTKTTTSGQGQCPGQDMEPQRERERKPILGIYLVGWGIALLICGISSAVNLAEYATYD----YCFLHSSTTLNALLVPAVILVIFCGILALCIYYQLSQQAVNVLQLQMQHQQNRQYSDNNTQATEHIDLDWLDANGSATTAAIGGGSGNHGGRKEQDHMQEQYSTLSNPLSSIVDDFERSNLSHLRGHFIFLVLYAGAWLSAAAYVNGG---QELYVLSFAGCCSVLGIFLLIFYNLSRNDARQAWSQGRDGRSIPAKLVTYNNGSQARGAHPSSMMPGPGTAMISNSIVAYKANPGPGSLYEANNSAGSRSNSQCSRSMRSQTRSQTRSQQEQLLQANGAGGVTIINNTSGQPGAGGGPAAGGVSGSTGGAPVPPHSLNALLHGSSHDLIPSAEIFYNPNQINVARKFFKKQKRLAKRNNFELQRQTMPQMQLQMQMQMQLHSQHSLSDASSEQLYSRHHNAMTMLAGGSKINNTNLHYKNQGSPMAGAPKEHGNMGAMSSGGDSMQFKRFVPASASSASKIMQANIYTNIPETLTPQHEVIKLRANGRTRTPSLLDETLHELDDDEEDEEEEEHGQTPATMEEPEHELEEEDASSLDEHAPLYANTLPPASGMSSLFRNRGSSHQPMSSTPVKQPSLEAMNSLGLPEVSLEEPLLQKHEIYVSNSLQVTTSNSIQLDDDFPSVLIRFSQQQQSKSLNNISEMLAGGGGGGGNAPGLDSLGDQQESSQLSVNEGSTLEEQQLRQIYSCSSSNLSQLKGHHPTATVDTEDDGRLLSGSPTNESDLNYQNSEISIRSHGLYAPQADNDLNLTLTDDFRCYQSSNASDADVDVLNEFDDEFVAATGGERVVGDAEQDPHHDHDQDTSIDELYEAIKCRSPLRNKQEAVERFERERERDREKEMEMEAKPLSNSHNENLNETIEDDSSQSSVISYIDPRAANEPRPFPS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :*. . * .:: .*** .::: * . :*: :. :**.* * *:* : . .*: ** : *: :*: :** *. :**: .: .: *.::* . . * : .:: :**:. *:.::* *:::*.*: :*.: * **:: ..:*..: *:.::.:. : * * ** ::. . :*: ::::: : : : . . * .. : *:* ::**. : *.*: .:* .* *. * : :: :.. . .**:*:** : .*:*. : * . * : * *: . . . .. *. : . .: : :.:. . * :* .: :: : .*.. :. :.* . :: . .:. . :.* .. . : . . : *: : : : .. . . .. :*.: . . . .. ::. *.: :*. .**: : ", "identical_positions": 78, "similar_positions": 198, "identity": "4.32%" }, { "cls_id": "homologset.agr.RGD:1308244", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L833-1", "uniprot_id": "A0ABK0L833_RAT", "id": "A0ABK0L833-1", "name": "", "aln": "MRAPGPGGRRGPRRGRGSRGGRDSGGRARGAGARGRDRAPAGPGRAGGAARRRAGPGRRGAGRGRGRGRGEPPAPRRRSLAPTRSLGRAAQRPPPLRAALAGAGPPPPSARAAARGRRRGARGQSVRRSGGGPGRGGGSRGGGRCPGGRRRSMWRTRWDAGILKAEALALLPCGLGMAFSQSHVMASRRHQHGRLIIEVDEYSSNPTQAFTFYNINQGRFQPPHVQMVDPVPHDAPKPPGYTRFVCVSDTHSRTDPIQ--MPYGDVLIHAGDFTELGLPSEVKKFNEWLGSLPYEYKIVIAGNHELTFDQEFMADLIKQDFYY-------------FPSVSKLKP-----ENYENVQSLLTNCIYLQDSEVTVRGFRIYGSPWQPWFYGWGFNLPRGQALLEKWNLIPEGVDILITHGPPLGFLDWVPKKMQRVGCVELLNTVQRRVQPRLHVFGHIHEGYGVMADGTTTYVNASVCTVNYQPVNPPIVIDLPTP---RNS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91ZG2-1", "uniprot_id": "MPPD1_MOUSE", "id": "Q91ZG2-1", "name": "Metallophosphoesterase domain-containing protein 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------MWRPRWDPGILKAEALALLPCGLGMAFSQSHVMASRRHQHGRLIIEVDEYSSNPTQAFTFYNINQGRFQPPHVQMVDPVPHDAPKPPGYTRFVCVSDTHSRTDPIQ--MPYGDVLIHAGDFTELGLPSEVKKFNEWLGSLPYEYKIVIAGNHELTFDQEFMADLIKQDFYY-------------FPSVSKLKP-----ENYENVQSLLTNCIYLQDSEVTVRGFRIYGSPWQPWFYGWGFNLPRGQALLEKWNLIPEGVDILITHGPPLGFLDWVPKKMQRVGCVELLNTVQRRVQPRLHVFGHIHEGYGVMADGTTTYVNASVCTVNYQPVNPPIVIDLPTP---RNS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15442-1", "uniprot_id": "MPPD1_HUMAN", "id": "O15442-1", "name": "Metallophosphoesterase domain-containing protein 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------MWRSRWDASVLKAEALALLPCGLGMAFSQSHVMAARRHQHSRLIIEVDEYSSNPTQAFTFYNINQGRFQPPHVQMVDPVPHDAPKPPGYTRFVCVSDTHSRTDPIQ--MPYGDVLIHAGDFTELGLPSEVKKFNEWLGSLPYEYKIVIAGNHELTFDQEFMADLIKQDFYY-------------FPSVSKLKP-----ENYENVQSLLTNCIYLQDSEVTVRGFRIYGSPWQPWFYGWGFNLPRGQALLEKWNLIPEGVDILITHGPPLGFLDWVPKKMQRVGCVELLNTVQRRVQPRLHVFGHIHEGYGVMADGTTTYVNASVCTVNYQPVNPPIVIDLPTP---RNS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VT29-1", "uniprot_id": "Q9VT29_DROME", "id": "Q9VT29-1", "name": "Calcineurin-like phosphoesterase domain-containing protein", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEVPVHPLSQDPTAAWREISKTQRVIK---VTMKPPTTTVAPN---KARVVCMSDTHSLTPYIKFDIPDGDIFIHAGDFTKCGQLEEVEEFNTWIGALPHRHKIVIAGNHELSFDRTFTHPFQKSKSHASSSKHTGMSILDDLPTLGNAKENLESAVQTQNVRDVLTNCRYLEDELLEIWGIQIYGSPWQPEFCRWAFNVPRGTACLDKWNQIPEGIDILVTHTPPVGHGDLCCSGVR-AGCVELLSTVQQRVRPKYHVFGHVHEGYGITSDGRIIFVNASTCDINYLPNNAPIVFDVTLPPGFRKD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : *. *.:** *: . .* :: * * *.. **: :*.**:***** * *: :* **::*******: * .**::** *:*:**:.:**********:**: * : *.. : :*::.: * : :**:.:**** **:*. : : *::******** * *.**:*** * *:*** ****:***:** **:*. * . :: .******.***:**:*: *****:*****: :** :****.* :** * *.***:*:. * *:.", "identical_positions": 138, "similar_positions": 78, "identity": "27.54%" }, { "cls_id": "homologset.agr.RGD:1308245", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5BJQ0-1", "uniprot_id": "COQ8A_RAT", "id": "Q5BJQ0-1", "name": "Atypical kinase COQ8A, mitochondrial", "aln": "MAAMLGDAIMVAKGLAKLTQAAVETHLQN--------------LGLGGELILAARALQSTAVEQISMVFGKVQGQDKHEDSYATENFEDLEAEVQFSTPQAAGSSPDFSTASSLDQPLSSSLGHAHREGPAPAYVSSGPFREAGLSGQATSPLGRVNGRLFVDCRDLFLANSIQRRFFHQDQAPVG--------GLTAEDIEKARQAKARPESKPHKQMLSERARERKVPVTRIGRLANFGGLAVGLGFGALAEVAKKSLRSENSTG-KKAVLDSSPFLSEANAERIVSTLCKVRGAALKLGQMLSIQDDAFINPHLAKIFERVRQSADFMPLKQMTKTLNNDLGPHWRDKLEYFEERPFAAASIGQVHLARLKGGREVAMKIQYPGVAQSINSDVNNLMAVLNMSNMLPEGLFPEHLIDVLRRELTLECDYQREAAYAKKFRELLKDHPFFYVPEIVDELCSPHVLTTELITGFPLDQAEGLSQEVRNEICYNILVLCLRELFEFHVMQTDPNWSNFFYDPQQHKVALLDFGATREYDRSFTDLYIQVIRAAADQDREAVLKKSIEMKFLTGYEVKAMEDAHLDAILILGEAFA--SEEPFDFGTQSTTEKIHNLIPIMLKHRLIPPPEETYSLHRKMGGSFLICSKLKACFPCKAMFEEAYSNYC--RMKSGLQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60936-1", "uniprot_id": "COQ8A_MOUSE", "id": "Q60936-1", "name": "Atypical kinase COQ8A, mitochondrial", "aln": "MAAMLGDAIMVAKGLAKLTQAAVETHLQN--------------LGLGGELLLAARALQSTAVEQFSMVFGKVQGQDKHEDSYATENFEDLEAEVQFSTPQAAGTSLDFSAASSLDQSLSP----SHSQGPAPAYASSGPFREAGLPGQATSPMGRVNGRLFVDHRDLFLANGIQRRSFHQDQSSVG--------GLTAEDIEKARQAKARPESKPHKQMLSERARERKVPVTRIGRLANFGGLAVGLGIGALAEVAKKSLRSENSTG-KKAVLDSSPFLSEANAERIVSTLCKVRGAALKLGQMLSIQDDAFINPHLAKIFERVRQSADFMPLKQMTKTLNSDLGPHWRDKLEYFEERPFAAASIGQVHLARMKGGREVAMKIQYPGVAQSINSDVNNLMAVLNMSNMLPEGLFPEHLIDVLRRELTLECDYQREAAYAKKFRELLKDHPFFYVPEIVDELCSPHVLTTELISGFPLDQAEGLSQEVRNEICYNILVLCLRELFEFHVMQTDPNWSNFFYDPQQHKVALLDFGATREYDRSFTDLYIQVIRAAADQDREAVLKKSIEMKFLTGYEVKAMEDAHLDAILILGEAFA--SEEPFDFGTQSTTEKIHNLIPVMLKHRLIPPPEETYSLHRKMGGSFLICSKLKARFPCKAMFEEAYSNYC--RMKSGLQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NI60-1", "uniprot_id": "COQ8A_HUMAN", "id": "Q8NI60-1", "name": "Atypical kinase COQ8A, mitochondrial", "aln": "MAAILGDTIMVAKGLVKLTQAAVETHLQH--------------LGIGGELIMAARALQSTAVEQIGMFLGKVQGQDKHEEYFA-ENFGGPEGEFHFSVPHAAGASTDFSSASAPDQSAPPSLGHAHSEGPAPAYVASGPFREAGFPGQASSPLGRANGRLFANPRDSFSAMGFQRRFFHQDQSPVG--------GLTAEDIEKARQAKARPENKQHKQTLSEHARERKVPVTRIGRLANFGGLAVGLGFGALAEVAKKSLRSEDPSG-KKAVLGSSPFLSEANAERIVRTLCKVRGAALKLGQMLSIQDDAFINPHLAKIFERVRQSADFMPLKQMMKTLNNDLGPNWRDKLEYFEERPFAAASIGQVHLARMKGGREVAMKIQYPGVAQSINSDVNNLMAVLNMSNMLPEGLFPEHLIDVLRRELALECDYQREAACARKFRDLLKGHPFFYVPEIVDELCSPHVLTTELVSGFPLDQAEGLSQEIRNEICYNILVLCLRELFEFHFMQTDPNWSNFFYDPQQHKVALLDFGATREYDRSFTDLYIQIIRAAADRDRETVRAKSIEMKFLTGYEVKVMEDAHLDAILILGEAFA--SDEPFDFGTQSTTEKIHNLIPVMLRHRLVPPPEETYSLHRKMGGSFLICSKLKARFPCKAMFEEAYSNYC--KRQAQQ-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5RGU1-1", "uniprot_id": "COQ8A_DANRE", "id": "Q5RGU1-1", "name": "Atypical kinase COQ8A, mitochondrial", "aln": "---MAGDMLLLMRGLARLSQAVIETQANS--------------LRSG-----GVQTMQMTAEQAMGVAMQKIQEFTGSQQSVS-DFSADMDSKYDFTASEQNFES---AAHGGLD--------------------SDSVFRDANTGAANTYSQAQGKSKLFDGYKDPTSQFTGHTRSYHQDHSSVG--------GITAEDIEKAREAKQN-GSKPHKQMLSERARERKVPVTRLGRLANFGGLAVGLGIGALAEVAKKSLRSEDKNGNKKAVLDSSPFLSEANAERIVRTLCKVRGAALKLGQMLSIQDDAFINPQLAKIFERVRQSADFMPIKQMTKALSNDLGPNWRDKLEMFEERPFAAASIGQVHLARMKDGREVAMKIQYPGVAQSINSDVNNLMTVLSMSNALPEGLFPEHLIDVMRRELALECDYIREAKCARKFKELLKDHPFFYVPDVISELSSQHVLTTELVPGFPLDQAEALTQELKNEICKNILNLCLRELFEFRYMQTDPNWSNFFYDPQTHRVALLDFGATRGFDESFTDVYIEIIKAAADGNREGVLKQSIDMKFLTGYESKAMVNAHVDAVMILGEAFA--SEEPFDFGAQSTTERIHNLIPVMLKQRLIPPPEETYSLHRKMGGSFLICSRLNAKISCKDMFEAAYSNYWSGRKKGPSQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E7F0M3-1", "uniprot_id": "E7F0M3_DANRE", "id": "E7F0M3-1", "name": "Atypical kinase COQ8A, mitochondrial", "aln": "MVKMAAD-MLLMRGINRFRNIRFRGRQK-----------------------------------QVSFLTPQLRGQVSCG----------HQTALSFSG-------------------------------------VMGVFGSD-------QHLSRLFGKIHPDQQHIYSQIG----FFHQDHRYYS--------ALKKEGVKG-----VKADSRKHNQKLSESARERKMPVTRIGRLVNFGGLAVGLGIGAIAEVAKKSFASRDNSGQKKAILDSNPFISEANAERIVRTLCKVRGAALKLGQMLSIQDDAFINPQLAKIFERVRQSADFMPAKQTMKMVVSDLGPNWQDHLEYFEERPFAAASIGQVHLARMKDGREVAMKIQYPGVAKSISSDINNLLTLLSISHALPEGLFPEHLIEVMSRELALECDYIREAKCAKKFQQLLKGHPFFSVPNVVDELSSKHVLTTELVSGFPLDKAEDLPQELKNEICEQILILCLRELFEFRYMQTDPNWSNFFFDPQTHKVALLDFGATRGFDASFTDTYIEIIKAAADRNREGVLQRSIDMKFLTGYESKSMVNAHVDAVMILGEAFS--SDEPFDFGSQSTTERIHRLIPVMLKERLTPPPEETYSLHRKMGGSFLICSRLKAQICCKNMFQEAYAKYWRERHKETAQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P27697-1", "uniprot_id": "COQ8_YEAST", "id": "P27697-1", "name": "Atypical kinase COQ8, mitochondrial", "aln": "------------------------------------------MVTNMVKLRNLRRLYCSS------RLLRTIQN--------------------------GRISSVSSISLSKKYTTKSAK-----------------EGEENVERKHEEE----------------KKDT----------------------------------------------------LKSSSVPTSRISRLFHYGSLAAGVGMNAAAKGIS-EVAKGNSPTWKSLIL------SDSNIDRITNKFSKMRGVALKIGQLLSFQDEKVLPKELYEILSRVQNSANHMPQRQLEKVMAKELGANWKTKFSKFDKIPMAAASIGQVHAAELPSGQRVVVKIQYPGVKESIDSDLNSLLMLLTASSLLPKGLFLDKTIANARTELKWECDYNREARALQKFEALLKDDPAFEVPHVFPEYTTDNIITMTRMEGTEIMKLPKASQETKNFISENIMRLCLEEIATFKYMQTDPNWANFLYNGRTKKIELLDFGASRPFAEDFILKYRKLLTYATLRDRKGAYEMSVQLGYLTGLESQSMKDAHVDSVLTLGEPFRGDVDKSFDFKDQTVSDRIRGNIGLMLNERLCPPPEETYSLHRKFSGIFLLCARMGASVHCAKLFKEIFAYKV---------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VYI6-1", "uniprot_id": "Q9VYI6_DROME", "id": "Q9VYI6-1", "name": "", "aln": "MSRSAQEAAALLRGLRILLEACGREHLAHGRHLWSNSSIRELIAENVAHTQQLVRSSSQNPTEELKKLQQTVKETGERGYVVAKGICSLLETKIKMSREESAISEPAQVSSIRKSTPTAQNPASWDAANLDISSITLQEFEEILSRRNKDRSVSLRTPATKSNQTMPKKETSTNPGIITQDTEYVNNVLRFVAGAKVEEQPPDAQPKKKSDQPAIEVPELSKVAKQRKVPSSRIGRMASFGGLFAGLGLGTLNELTKGALGLGGSTSMREALL------SPANAERIVDTLCKVRGAALKIGQILSIQDSSVVSPQLAKAFERVRQAADYMPDWQVERVMNTQLGADWRQRLKSFEDKPFAAASIGQVHRATLSDGMDVAIKIQYPGVAQSIESDIDNLVGMLKVWDVFPQGFFIDNVVRVAKRELQWEVDYDREAEYTEKFREMIAPYPEYYVPRVVRDLTTSSVLTTELVPGVPLDKCFDLSYEHRRHIAASVLKLCLRELFEIECMQTDPNWSNFLYDAPSRRLMLIDFGSTRFYRHEFIRNYRRVIMSAAENNRQGVLEMSREMGFLTGYETKQMEQAHVDAVMILGEIFR--YDGDFDFGRQNTTERLAALVPTMVAHRLCPPPEEIYSIHRKLSGIFLLCARLNVRMNCVPFYKDIVLGKFKD-------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: . :. .:* :*:.*: :*.* .*:*:.: : . . . :. :* * :* :**. .:.*:**.***:**:**:**. .: .* : :.**:::*:.** * : : .:**..*: ::. *:. *:********* * : .* *.:******* :**.**::.*: :*. :*:*:* :: : ** * ** *** .**. :: * : ** :. : : ::* : * : : . * :. *. .:: ***.*: :. *******:**::: ::: *:***::* : .* * .:: *: :*: . * :: :*** * : * :**:*::: *** * : *** *..:::: : *: .** ***** **:***:.* **:*::: . . * ::: ", "identical_positions": 138, "similar_positions": 154, "identity": "20.41%" }, { "cls_id": "homologset.agr.RGD:1308247", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "F7F6Z7-1", "uniprot_id": "F7F6Z7_RAT", "id": "F7F6Z7-1", "name": "DNA-directed DNA/RNA polymerase mu", "aln": "MLPKRRRRVRAGSPHSALASSTPP-AARFPGVAIYLAEPRMGRSRR--------AFLTR---------LARSKGFRILDVYSSEVTHVVMEETSAKEAICWQKD-MNALLPDCPQPALLDISWFTESMAAGQPVPE-EVRHRLEVAEPRKEPPISVTIPAYACQRPSPLT---------------PHNTLLSEALETLAEAAGFEGKEGRFLTFYRAASMLKSLPYPVTSLSQLHG-LPYFGEHSFRVIQELLEHGTCEEVEQIRCSERHQTMKLFTHIFGVGVKTASRWYQEGLRTLDELREQ-PQRLTQQQKAVLPTGLQYYQDLSTPVSRAEAEALQQLVEAAMREILPGATVTLTGGFRRGKLQGHDVDFLITHPEE-------------------------------GQEVGLLPRVMRCLQSQGLVLYHQYHRSHLADSAHILRQRS-TMDAFERSFCILR-----LPQSQQAALEGPLHPCPTWKAV---------RVDLVVTPNSQFPFALLGWTGSQFFERELRRFSRQEKGLCLNSHGLFDPERKTFFHATSEEDVFRFLGLKYLPPEQRNA-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JIW4-1", "uniprot_id": "DPOLM_MOUSE", "id": "Q9JIW4-1", "name": "DNA-directed DNA/RNA polymerase mu", "aln": "MLPKRRR-VRAGSPHSAVASSTPPSVVRFPDVAIYLAEPRMGRSRR--------AFLTR---------LARSKGFRVLDAYSSKVTHVVMEGTSAKEAICWQKN-MDALPTGCPQPALLDISWFTESMAAGQPVPE-EGRHHLEVAEPRKEPPVSASMPAYACQRPSPLT---------------HHNTLLSEALETLAEAAGFEANEGRLLSFSRAASVLKSLPCPVASLSQLHG-LPYFGEHSTRVIQELLEHGTCEEVKQVRCSERYQTMKLFTQVFGVGVKTANRWYQEGLRTLDELREQ-PQRLTQQQK----AGLQYYQDLSTPVRRADAEALQQLIEAAVRQTLPGATVTLTGGFRRGKLQGHDVDFLITHPEE-------------------------------GQEVGLLPKVMSCLQSQGLVLYHQYHRSHLADSAHNLRQRSSTMDAFERSFCILG-----LPQPQQAALAGALPPCPTWKAV---------RVDLVVTPSSQFPFALLGWTGSQFFERELRRFSRQEKGLWLNSHGLFDPEQKRVFHATSEEDVFRLLGLKYLPPEQRNA-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NP87-1", "uniprot_id": "DPOLM_HUMAN", "id": "Q9NP87-1", "name": "DNA-directed DNA/RNA polymerase mu", "aln": "MLPKRRR-ARVGSPSGDAASSTPP-STRFPGVAIYLVEPRMGRSRR--------AFLTG---------LARSKGFRVLDACSSEATHVVMEETSAEEAVSWQERRMAAAPPGCTPPALLDISWLTESLGAGQPVPV-ECRHRLEVAGPRKGPLSPAWMPAYACQRPTPLT---------------HHNTGLSEALEILAEAAGFEGSEGRLLTFCRAASVLKALPSPVTTLSQLQG-LPHFGEHSSRVVQELLEHGVCEEVERVRRSERYQTMKLFTQIFGVGVKTADRWYREGLRTLDDLREQ-PQKLTQQQK----AGLQHHQDLSTPVLRSDVDALQQVVEEAVGQALPGATVTLTGGFRRGKLQGHDVDFLITHPKE-------------------------------GQEAGLLPRVMCRLQDQGLILYHQHQHS-CCESPTRLAQQS-HMDAFERSFCIFR-----LPQPPGAAVGGSTRPCPSWKAV---------RVDLVVAPVSQFPFALLGWTGSKLFQRELRRFSRKEKGLWLNSHGLFDPEQKTFFQAASEEDIFRHLGLEYLPPEQRNA-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P25615-1", "uniprot_id": "DPO4_YEAST", "id": "P25615-1", "name": "DNA polymerase IV", "aln": "MSLKGKFFAFLPNPNTSSNKFFKSILEKKGATIVSSIQNCLQSSRKEVVILIEDSFVDSDMHLTQKDIFQREAGLNDVDEFLGKIEQSGIQCVKTSCITKWVQNDKFAFQKDDLIKFQPSIIVISDNADDGQSSTDKESEISTDVESERNDDSNNKDMIQASKPLKRLLQGDKGRASLVTDKTKYKNNELIIGALKRLTKKYEIEGEKFRARSYRLAKQSMENCDFNVRSGEEAHTKLRNIGPSIAKKIQVILDTGVLPGLNDSVG--LEDKLKYFKNCYGIGSEIAKRWNLLNFESFCVAAKKDPEEFVSDWT--ILFGWSYYDDWLCKMSRNECFTHLKKVQKALRGIDPECQVELQGSYNRGYSKCGDIDLLFFKPFCNDTTELAKIMETLCIKLYKDGYIHCFLQLTPNLEKLFLKRIVERFRTAKIVGYGERKRWYSSEIIKKFFMGVKLSPRELEELKEMKNDEGTLLIEEEEEEETKLKPIDQYMSLNAKDGNYCRRLDFFCCKWDELGAGRIHYTGSKEYNRWIR-ILAAQKGFKLTQHGLFR--NNILLESFNERRIFELLNLKYAEPEHRNIEWEKKTA", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * : . .* . . : . : : : **: :*: : *. *:. :* .: : :: ..:. * : * . .* :::. **. . * . :* *: : : * :* : **: *:: :*..: * :: * . :: * : .: : * :* : :* :*: *. :: :.:* *.: :*:* : *.** .:.:: :: *:.:..: . * .:::* : * : : : :: *: * . * * *.:.** : *:*:*: :* . * :* ::: :: :: * : :: .: : ..: : * * : :: *:*:. .:: . : :***: ::* :* : :**: *..**** .: .:.: .*. :*. *.*:* **:** ", "identical_positions": 81, "similar_positions": 163, "identity": "13.75%" }, { "cls_id": "homologset.agr.RGD:1308248", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5FVH2-1", "uniprot_id": "PLD3_RAT", "id": "Q5FVH2-1", "name": "5'-3' exonuclease PLD3", "aln": "MKPKLMYQELKVPVEEP---AGELPMNEIEAWKAAEKKARWVLLVLILAVVGFGALMTQLFLWEYGDLHLFGPNQHP-APCYDPCEAVLVESIPEGLEFPNATTSNPSTSQAWLGLLAGAHSSLDIASFYWTLTNNDTH-TQEPSAQQGEEVLQQLQALAPRG-----VKVRIAVSKPNGP--LADLQSLLQSG-AQVRMVDMQKLT-HGVLHTKFWVVDQTHFYLGSANMDWRSLTQVKELGVVMYNCSCLARDLTKIFEAYWFLGQAGSSIPSTWPRPFDTRYNQETPMEICLNG-TPALAYLASAPPPLCPGGRTPDLKALLSVVDNARSFIYIAVMNYLPTMEFSHPRRFWPAIDDGLRRAAYERGVKVRLLISCWGHSEPSMRSFLLSLAALRDNHTHSDIQVKLFVVPADEAQARIPYARVNHNKYMVTERTTYIGTSNWSGSYFTETAGTSLLVTQNGHGG----LRSQLEAVFLRDWESPYSHNLDTSADSVGNACRLL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35405-1", "uniprot_id": "PLD3_MOUSE", "id": "O35405-1", "name": "5'-3' exonuclease PLD3", "aln": "MKPKLMYQELKVPVEEP---AGELPLNEIEAWKAAEKKARWVLLVLILAVVGFGALMTQLFLWEYGDLHLFGPNQRP-APCYDPCEAVLVESIPEGLEFPNATTSNPSTSQAWLGLLAGAHSSLDIASFYWTLTNNDTH-TQEPSAQQGEEVLQQLQALAPRG-----VKVRIAVSKPNGP--LADLQSLLQSG-AQVRMVDMQKLT-HGVLHTKFWVVDQTHFYLGSANMDWRSLTQVKELGVVMYNCSCLARDLTKIFEAYWFLGQAGSSIPSTWPRSFDTRYNQETPMEICLNG-TPALAYLASAPPPLCPSGRTPDLKALLNVVDSARSFIYIAVMNYLPTMEFSHPRRFWPAIDDGLRRAAYERGVKVRLLISCWGHSDPSMRSFLLSLAALHDNHTHSDIQVKLFVVPTDESQARIPYARVNHNKYMVTERASYIGTSNWSGSYFTETAGTSLLVTQNGHGG----LRSQLEAVFLRDWESPYSHDLDTSANSVGNACRLL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IV08-1", "uniprot_id": "PLD3_HUMAN", "id": "Q8IV08-1", "name": "5'-3' exonuclease PLD3", "aln": "MKPKLMYQELKVPAEEP---ANELPMNEIEAWKAAEKKARWVLLVLILAVVGFGALMTQLFLWEYGDLHLFGPNQRP-APCYDPCEAVLVESIPEGLDFPNASTGNPSTSQAWLGLLAGAHSSLDIASFYWTLTNNDTH-TQEPSAQQGEEVLRQLQTLAPKG-----VNVRIAVSKPSGPQPQADLQALLQSG-AQVRMVDMQKLT-HGVLHTKFWVVDQTHFYLGSANMDWRSLTQVKELGVVMYNCSCLARDLTKIFEAYWFLGQAGSSIPSTWPRFYDTRYNQETPMEICLNG-TPALAYLASAPPPLCPSGRTPDLKALLNVVDNARSFIYVAVMNYLPTLEFSHPHRFWPAIDDGLRRATYERGVKVRLLISCWGHSEPSMRAFLLSLAALRDNHTHSDIQVKLFVVPADEAQARIPYARVNHNKYMVTERATYIGTSNWSGNYFTETAGTSLLVTQNGRGG----LRSQLEAIFLRDWDSPYSHDLDTSADSVGNACRLL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1L8A0-1", "uniprot_id": "Q1L8A0_DANRE", "id": "Q1L8A0-1", "name": "5'-3' exonuclease PLD3", "aln": "MKSDIPYEKM-VDVELS---RGEGHHGSQKYYRCLIVLT--CITTVLLILLSLQTLLVPMAKSSSTKSSVQQERVLIRETCTDPCRIVLVESIPEGMVFN--SSVHQSIYDAWLNLISATQSSLDIASFYWTLTNSDTH-TQEPTANQGQQILKKLGQLSSK------AYVRIAVDKPADKKPMEDINFLSSYG-ADVRMVNMRELT-TGVLHTKFWIVDKKHIYIGSANMDWRSLTQVKELGAVVYDCSCLAEDLGKIFEAYWYLNQT-KTVPAHWPNKYSTLYNKDTPMQLSLNG-TSASVYLSSSPPSLCAEGRTPDLQSILDVIANAQQFVYIAVMNYLPTMEFSRSKRYWMDIDTELRRVAYERRIRVRLLISCWNSTKPIMFPFLRSLASLQDTN-QLDIQVRIFTVPSDAQQKKIPFARVNHNKYMVTDQVAYIGTSNWSGDYFVNTAGSALVVNQTSASASS-TVQEQLQAVFERDWESAYSTDINHRSNRK-DIC---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VIF2-1", "uniprot_id": "Q9VIF2_DROME", "id": "Q9VIF2-1", "name": "", "aln": "MPEYKKLEDQESDVENANRTTVQNTATVQDAGEGQRQAAGQQAGQMVTVSLFMLLFLGSSYFQPRPRLHQYKGGRGHGLLEKFDCNIQLVESIPIGLTYPDGSPRFLSTYEAWLELLESATTSLDIASFYWTLKAEDTPGVSDNSTRPGEDVFARLLANGNGGSRSPRIKIRIAQSEPSSGTPNLNTKLLASAGAAEVVSISFPKYFGSGVLHTKLWVVDNKHFYLGSANMDWRALTQVKEMGVLVQNCPELTHDVAKIFGEYWYLGNSESSRIPDWDWRYATSYNLKHPMQLSVNKNTSIEGFLSSSPPPLSPSGRTDDLNAILNTINTAITYVNIAVMDYYPLIIYEKNHHYWPFIDDALRKAAVERGVAVKLLISWWKHSNPSEDRYLRSLQDLASKEDKIDIQIRRFIVPTDSSQEKIPFGRVNHNKYMVTDRVAYIGTSNWSGDYFTDTAGIGLVLSETFETETTNTLRSDLRNVFERDWNSKYATPLV-------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :. .* . : . . : :: : : :: *. ****** *: : :. * :*** *: .: :***********. .** ..: ::. *:::: :* . :*** .:* . : : * . * *:* :.: : ******:*:**:.*:*:********:******:*.:: :*. *:.*: *** **:*.:: .: . * : * ** . **::.:* *. :*:*:**.*.. *** **:::*..: .* :: :***:* * : :.: :::* ** **:.: ** : *:**** * :.* :* ** * ... : ***:: * **:* * :**:.**********::.:*********.**.:*** .*::.:. ::.:*. :* ***:* *: : ", "identical_positions": 158, "similar_positions": 144, "identity": "31.16%" }, { "cls_id": "homologset.agr.RGD:1308250", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A3KGK3-1", "uniprot_id": "FR1L4_MOUSE", "id": "A3KGK3-1", "name": "Fer-1-like protein 4", "aln": "MALTVCVRHLTGLPGTHDRQVRLCFRGFTQKTRKIHCGREADVGELFRWPHYGSPLAGESLSVQVVNCSRVFSPRPLGTLVISLQQLQSAGHLVLREALVDERLRVSPIQVELDLKYQPPEGAAGTWAEEDFGTPIRDSLELIIPNVGFQDMEPGEAQLERRAVALGRRLARSLGTQDDEENELELEPELEEEPDVEISGVVFSPLKSRALGLPRGDPFKVCKAQDFQVGVTVLEAQKLVGVNINPYVAVRVGDQRKVTATLRGTNCPFYNEYFLFEFHETRLHLQDLLLEITAFHSQTLPFMATRIGTFRMDLGMALDQPDGHFHQKWAPLHDPRDTRAGTKGFVKITLSVRARGDLPLPPPPPCPGTSSDIEKNLLLPHGVQAERPWARLRVRVYRAEGLPTVRTGLLGSLARALHDQNVLLDPYVRVSFLGQQGETSVRGEETAPKWNEQLSFVELFPPLTRSLRLQLRDNAPLVDVALATHVLDLRQISNSGRAAGFNPTFGPAWVPLYGSLPSGRLRDDLQSLNEGLGEGIWFRGRLLVAVSMEVYEGRVEPKPSQTTQRSGLSRLTGKKKKKKEKTRQGQTPAGILQPASASTSEDAPEIPSAMEVEVEDLLPLPENALASFEDFLLFGVLFEATMIDPSLAKKPISLEISIGHAGRQEEQSGQGSRADEGSESSTLEVQPLLESEDRGAGQEEQELLGTPAQWPEPVDGNGPYLCLPLRHRKPCLHVWSCWEDYTWRLQSSNSVCKVAERLDHGLQEVEKMQRRSGPGACTRLKQTLEELVAGSRQFCHGAERRTMTRPNALDRCRAKLLTHSLNLMARQGLRLLRSLRLNNMQRTVVLAKKLLARLRFLAQEPQPPLPDVLVWMFSGQRRVAYARIPAQDILYSVVEEERGRDCGKIQSLLLTVPGAAPGEVCAKLELFLWLGLGKQAKACTSELPMDLLPEPSSGLPQSLYRDDFRYFQLRAHLYQARGVLAADDSGLSDPFARVLISTQCQTTRVLEQTLSPLWDELLVFDQLIVDGRREHLREEPPLVVINVFDHNKFGPAVFLGRAFAAPRVKLIEDPYQR-------PELQFFPLRKGPQAAGEVIATFELIELDYSGHLEPSVPSDVEPRDLASLVEPISG--------HLSLPPSVRPVLRAFRVEVLFWGLRGLGRVHLFEIEKPQVVLEVAGRRVES-EVLPNYRENPNFTELVRHVTVDLPEQPYLQPPLSILVIERRAFGRTVLVGSHIVPHMLRFILQ----------------GHEDPQEEEETEEETRDLVPHGPQGEKSLPEAGTSRQLLKAPLKKLTLG----LLGQGPELEEDIPDPEEMDWWSKYYASLQEFQGQPSSDD-EMDEAGDADGTHLISGDREAQEQGETDSKVSVPRKKAIATLKIYNSSLEDEFSHFEDWLSVFPLYRGQGGQDGEGEGASGHFVGKFKGSFLIYPESEAKSFSEPQISRGVPQNRPIKLLVRVYIVKATNLAPADPNGKADPYVVVSAGKEQRDTKERYIPKQLNPIFGEVLELSVSLPAQPELTVAVFDHDLVGSDDLIGETHIDLENRFYSHHRANCGLASQYDVNGYNAWRDAFRPSQILAGLCQRCGLPVPEYRAGAVKVGSRVFLTPSEAPPPDDRKPKVTSEASEEAQALHVLRRWQEMPGLGIQLVPEHVETRPLYHPRSPGLLQGSLHMWIDIFPSDVPAPPPVDIKPRQPISYELRVVIWNTDDVALDDVNPLTGERSSDIYVKSWVKGLEQDRQETDVHFNSLTGEGNFNWRFVFRFDYLPTEREVSVRRKPGPFALEEAEFRQPAVLVLQVWDYDRISANDFLGSLELQLPDMVRGARDPEHCSVRLALDGAGPRCNLFRCHRLRGWWPVVKMKDMEDVEREAREAQAGKKRKRKRRAGRPEDLEFTDTGGNVYILTGKVEAEFELLTVEEAEKRPVGKGRKEPEPLEKPNRPKTSFNWFVNPLKTFIFFIWRRYWRIL-VLLLLALITIFLLLVFYTIPGQISEVIFSPVHK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4ABP2-1", "uniprot_id": "D4ABP2_RAT", "id": "D4ABP2-1", "name": "", "aln": "MALTVCVRHLTGLPGIHDRQVRLCFRGFTQKTRKIHCGREADVGELFRWPHYGSPLAGESLSVQVVNCSRVFSPRPLGTLVISLQRLQNTGHLVLREALVDERLRVSPIQVELDLKYQPPEGAAGTWAEEDFGAPIRDSLELIIPNVGFQDMEPGEAQLERRAVAMGRRLAQSLGTQDDEENELELELDLEE-PDVEISGVVFSPLKSRALGLPRRDPFKACKAQDFQVGVTVLEAQKLVGVNINPYVTVRVGDQRRVTATQRGTNCPFYNEYFLFEFHETRLHLQDLLLEITAFHSQTLPFMATRIGTFRMDLGMALDQPDGHFHQKWAPLHDPRDTRAGTKGFIKITLSVRARGDLPLPPPPSTPGTSADIEKNLLLPRGVQAERPWARLRVRVYRAEGLPTVRTGLLGSLARALHDQHVLLDPYVRVSFLGQQGETSVRGEETAPEWNEQLSFVELFPPLTRSLRLQLRDDAPLADVALATHMLDLRQISNSGRAAGFNPTFGPAWVPLYGSLPSGRFRDGLQGLNEGLGEGIWFRGRLLVAVSMEVFEGRVEPKSSQTTQGSGLSRLTGKKKKKKEKTKQGQTPAGTLQPANASTEVGVPEIPSSMEVDMEELLPLPENALAPCEDFLLFGVLFEATMIDPSLAKKPISLEISIGHAGRREEQLGPGSRADGGSEGSTLEAQPLLESEDRGAGQEEQELLGTPAQWPEPVEGNGPYLCLPLRHRKPCLHVWSRWEDYTWRLHSSNSVCKVAERLDHGLQEVEKIQRRSVLGACTRLKQTLEELVAGSRQFCHGAERRTMTRPNALDRCRAKLLTHSLNLMARQGLRLLRSLRQNNIQRTVALAKKLLAKLHFLAQEPQPPLPDVLVWMFSGQRRVAYARVPAQDVLFSVVEEERGRDCGKIQSLLLTAPGAAPGEVCAKLELFLWLGLGKQSKACPSELPPDLLPEPSRGLPHSLYRDDFSYFQMRAHLYQARGVLAADDSGLSDPFARVLISTQCKTTRVLEQTLSPLWDELLVFDQLIVDGKREHLREEPPLVVINVFDHNKFGSAVFLGRAFAAPRVKLIEDSYQR-------PELQFFPLRKGPQAAGEVIATFELIELDYSGHLEPSVPSDVEPQDLASLVEPISG--------HLSLPASVRPVLREFRVEVLFWGLRGLGRVHLFEVEKPQVVLEVAGRRVES-EVLANYCENPNFTELVQCVTVDLPEQPYLQPPLSILVIERRAFGRTVLVGSHIVPHMLRFTLQ----------------GQEDPREEERTEEETRGLVPQGLQGEKSLAEAGISRQRLKAPLKKLTLG----LLGQGPELEEAIPDPQEMDWWSKYYASLQELQGQSSSDDDEMDDARDPDGTHLISGEREAQEQGETDIKVSVPRKKAIATLKIYHSSLEDEFNHFEDWLSVFPLYRGQGGQEGDGEEASGHFVGKFKGSFLIYPESEAKSFSEPQISRGIPQNRPIKLLVRVYIVKATNLAPADPNGKADPYVVVSAGKEQRDTKERYIPKQLNPIFGEVLELSVSLPAEPELTVAIFDHDLVGSDDLIGETHIDLENRFYSHHRANCGLASQYDVDGYNAWRDAFRPSQILAGLCQRCGLPIPEYRAGAVKVGSRVFLTPSEALPPDGRDPKGANEASEEAQALLVLRRWQEMPGLGIQLVPEHVETRPLYHPRSPGLLQGSLHMWIDVFPSDVPAPPPVDIKPRQPISYELRVVIWNTDDVVLDDVNPLTGEMSSDIYVKSWVKGLEHDRQETDVHFNSLTGEGNFNWRFVFRFDYLPTEREVSIRRKPGPFALEEAEFRQPAVLVLQVWDYDRVSANDFLGSLELQLPDMVRGARDPEHCTVRLALDGAGPRCNLFRCRRLRGWWPVVKTKDMEDVEREAREAQAGKKRKRKRRKGWPEDLEFTDTGGNVYILTGKVEAEFELLTVEEAEKRPVGKGRKEPEPLEKPNRPKTSFNWFVNPLKTFVFFILRRYWRILVVLLLLALITIFLLLVFYTIPGQISEVIFSPINKH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B7Z0E5-1", "uniprot_id": "B7Z0E5_DROME", "id": "B7Z0E5-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSYMDDCFAGAPQEFLICITVHKAAQVGVTTGELYVRISLDKMTKSTKSFPNTENPFFNEYFVFEFHCTLTELLRLTILFELKKHMTY-KKNVVVGELLVDLHSVWNQSNHGYFKKWGRLEAPIGENQTLENAVAPHGYLQLDLAIVSQHSPVSYALGSEEQDTQNLNKWTVDHDFDDIEKNLLTNVNIFAPSNIRYFVAFYRGYFIK--QSNYMIQVSFAGFNGKTPVVKNTTTPVWNYEINFAWMYPSVAQRFLILIFAHEHLQWKCVAEFELCLEEIAFNG-----TPSLGPTYLHLYDPVNP-----------------MIYVGRLLMELRSEMLTDSQPTHTLSSKTVPGLDETRFWHDDVYLIEFLPLMGHHILTSGTAYKISARLAEHTSNVLEGQLRTPLDRFKSAMNSKNFRREAPFQSCMFRVRLPDNRAKYESDFFMLDIVN------------YMRSELDTFKLFQRKYPLQDDEQAKCLKVIVNNILTRIKEGLDAHRFDHDVQPQRTTW----DINRQLYLLDYFAKLPLELQNLKQKLRSCFLEHLDTSIGDVVNELQRLVAEIGSLSS------------MARTQDEWPELVLSLSASG--------------KDVGVCRLNAKLFLNLRNQDADQDQETLCWRLKS---------------FSFKSAGCSHTCPNCGCTTAIVSGCLS--IVVERERKRFLAVVNKEWANIEPMLWQLNPEQ-------------THFLCHVYIHQAKVRPGGEKKNICDSHLRVLFADQACETYTSPGTLSPIWNAVITFNWVSLPGGIGLYLKNPPLLSLEFYNSERSLPEDLVGMGSVAMSVISEDRASDSNWEDAGVFGCSKNPLRKLQRLKYLTPPPLKWVPIARKGTLQAEVLMSAEIIQISMESLTTGQNDKKEPQLATGIPMAIRPTMQNFVLEVFFVGLRNYSKSSMSSAGKRKINLMMGDLVLSSGPSTARIRNSINFLVAYASGVVSLPDQQDYWPAIIATDVLLSGFSSESILGAALIPNSSNFLQRDRTLKCVFKKEQEAAEASTTVSVDEDDEDEEEELEWEEEETKPSRISSWWMRLLFAFGLRPAPYANRHALRFHDDLDDHELVEEREFTWWTKFYNSMYWSAAEMCHEH------KHRLVIYYEELEKQAQFGYLQDWAVPVQLVHGVK-FKKHGPPKEDIYATLKLQLKLTPCQCPVLEDPGGG----GDMVRNMSNPIHPRHQSTLQSLGET-----------VKLLVRVYVVQGVQMRPRDVKGDSDCYVKLFLGGKTFSDRAHFSPNHSNPVFGRLFEMEATLPGDHMLQVMVYDHDKIK-DEVIGQTNIDLEDRWRTRHRATVGLANEYTKSGYNHWHDVKLPSEILIDLCQKRGIQAPYYYGNVIEVDGMLFG---------DETLISKDEELQERLSLAVLKNMDKLPSFGYKLVPEHVETRSLCRDDFPNVEQGKLQLWIELFEANIYVPSPIDITPVPPADFEVRVVVKNLVGIQAGDKN-IFGKLMSDVYVIGWCE-DEDKRQSTDIHYRSFAGDAAFNWRMVFGLKYSPNEDLMVIRRKAG--LLEEIEFKKPPIIYLQVWDKDVLTKDEYLAALELNLSNMYAPYPAAQLCKP---YPKKRKRINLFKRKVINGWFPLQSN-------------------------------AHPSQRSQAAVQNGKMQLSIEVCTDVEAVNRPAGRGQDPPMALEPPYRPDSSFNPLTHPCKSFQHILWPVIRKYVLWTLLILIVILGLVLFFSNLPAKLMTIPLE-----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. * . .*:* : :** :* :: .. : ** : :.. : * : .*: **:****:**** * .* * : : : * . :* : :** . :*.: :.:**. *. * . . :. : :: : .* . .:: :.. * : . . : : ..: :.. . : :: *. . : : ::*** * :*:*.* : *:* ** ::.*. ::*.::: : : : . * .:* . * *.:*: .* .*::**::: **..: . : : ****: : *: . .:. .:. .**.. :.. * ...* . :: :: : ** . * .. : . *:: *: *..: . * .: . : * *:. *:: : .:*: : * . .: . :* :. :* .* * . :* : ..*:. .*:: *::.. . : : : *:.*** .:. : * : : *.* * : * :.: : * :: :.* * :.. :*. . .: * : . ..*. . : .: * :*.: :: * . : :* ** :* :.:::**: ..:...:.*.. ***:: *. * . ****:*: ::.*: : : * ::***: ::.:: :: . ::* . .* * : . : . **** : . ..:: : : .* *:..* ..* ::: . . .:* ::**.:: * :**:* ***. .: : . * :: * :.. :.* .. :. ** .*.**:* *.: : .*. ::*: ::*: .* : . :* *:* . * . : : * .: * : *: . . * :. :. : : .*: **:*:* *: .: . :. . : . :::** * *.* :.: :* : .. ** : :: *.: * : * * *.:* ::...: :* :*:.*. :*******:*:..:: * * :*.:* ** : * : . : :: *:: **:**.::*:..:**.: * * ::*** : *::**:*:****:*: ::***. ***.:* .*** *:*. **:** .***: *: * * ...::*.. :* .. .* :* :* **:. :::*.:* :*********.* : *.: **.*::**::* ::: .*.*:**.* * .:*:***: * .: .* * : *: **:** .* : *..**.**:*:.*::*:. ****:** :.* *.* : :***.* *** **::*.:: ***** * :: :::*.:***:*.:* .: *. * ***: : :.**:*: . ... .:. : .**:: .:*: * ** :**.*:*:. * .** * **.:*** :.:* *:* .:: : : **: :: : *:*.* .:*.:: : :. ", "identical_positions": 373, "similar_positions": 589, "identity": "18.37%" }, { "cls_id": "homologset.agr.RGD:1308251", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LB38-1", "uniprot_id": "A0ABK0LB38_RAT", "id": "A0ABK0LB38-1", "name": "Prostamide/prostaglandin F synthase", "aln": "MSTLDLGRVGACVLKHAVTGEAVELRSLWQEKACVVAGLRRFGCMVCRWIAQDLSNLRGILDQNDVRLVGIGPEALGLQEFLDGGYFSGELYLDESKQIYKELGFKRYNSLSILPAALGKPVRDVASKAKAVGIQGNLSGDLLQSGGLLVVSKGGSGQDIEPHLACLGGPCPHSSQSGLGYQGGDRVLLHFIQSSPGDYVPQENILQALGISAEVCSSKPPQCDEEVCGR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DB60-1", "uniprot_id": "PXL2B_MOUSE", "id": "Q9DB60-1", "name": "Prostamide/prostaglandin F synthase", "aln": "MNVVDLGRVGACVLKHAVTGEAVELRSLWQEKACVVAGLRRFGCMVCRWIAQDLSNLRSILDQHDVRLVGVGPEALGLQEFLDGGYFSGELYLDESKQIYKELGFKRYNSLSILPAALGKPVRDVASKAKAVGIQGNLSGDLLQSGGLLVVSKGG-----------------------------DKVLLHFIQKSPGDYVPQENILQALGISAEVCSSKPPQCDEEVCGR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TBF2-1", "uniprot_id": "PXL2B_HUMAN", "id": "Q8TBF2-1", "name": "Prostamide/prostaglandin F synthase", "aln": "MSTVDLARVGACILKHAVTGEAVELRSLWREHACVVAGLRRFGCVVCRWIAQDLSSLAGLLDQHGVRLVGVGPEALGLQEFLDGDYFAGELYLDESKQLYKELGFKRYNSLSILPAALGKPVRDVAAKAKAVGIQGNLSGDLLQSGGLLVVSKGG-----------------------------DKVLLHFVQKSPGDYVPKEHILQVLGISAEVCASDPPQCDREV---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NV24-1", "uniprot_id": "PXL2B_DANRE", "id": "Q6NV24-1", "name": "Prostamide/prostaglandin F synthase", "aln": "MSSVNLTSLGANQLKNTTTGEMVEIGSLWREQAVVLFFLRRFGCQVCRWMAAEVSKLEKDLKAHGIALVGIGPEETGVKEFKDGGFFKGDIYIDEMKQCYKDLGFKRYNAINVVPAAMGKKVREIASKASAEGIQGNFSGDLLQSGGMLIVAKGG-----------------------------EKVLLHFIQKSPADNPPLEEITKALGISANVQAGEKPQCNEDVCTR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. ::* :** **::.*** **: ***:*:* *: ****** ****:* ::*.* *. :.: ***:*** *::** **.:* *::*:** ** **:*******::.::***:** **::*:**.* *****:*********:*:*:*** ::*****:*.**.* * *.* :.*****:* :.. ***:.:* ", "identical_positions": 110, "similar_positions": 57, "identity": "47.83%" }, { "cls_id": "homologset.agr.RGD:1308252", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q2AC31-1", "uniprot_id": "FFAR4_RAT", "id": "Q2AC31-1", "name": "Free fatty acid receptor 4", "aln": "MSPECAQTTGPGPSRTPDQVNRTHFPFFSDVKGDHRLVLSVLETTVLGLIFVVSLLGNVCALVLVVRRRRRGATVSLVLNLFCADLLFTSAIPLVLVVRWTEAWLLGPVVCHLLFYVMTMSGSVTILTLAAVSLERMVCIVRLRRGLSGPGRRTQAALLAFIWGYSALAALPLCILFRVVPQRLPGGDQEIPICTLDWPNRIGEISWDVFFVTLNFLVPGLVIVISYSKILQITKASRKRLTLSLAYSESHQIRVSQQDYRLFRTLFLLMVSFFIMWSPIIITILLILIQNFRQDLVIWPSLFFWVVAFTFANSALNPILYNMSLFRSEWRKIFCCFFFPEKGAIFTETSIRRNDLSVIST", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TMA4-1", "uniprot_id": "FFAR4_MOUSE", "id": "Q7TMA4-1", "name": "Free fatty acid receptor 4", "aln": "MSPECAQTTGPGPSHTLDQVNRTHFPFFSDVKGDHRLVLSVVETTVLGLIFVVSLLGNVCALVLVARRRRRGATASLVLNLFCADLLFTSAIPLVLVVRWTEAWLLGPVVCHLLFYVMTMSGSVTILTLAAVSLERMVCIVRLRRGLSGPGRRTQAALLAFIWGYSALAALPLCILFRVVPQRLPGGDQEIPICTLDWPNRIGEISWDVFFVTLNFLVPGLVIVISYSKILQITKASRKRLTLSLAYSESHQIRVSQQDYRLFRTLFLLMVSFFIMWSPIIITILLILIQNFRQDLVIWPSLFFWVVAFTFANSALNPILYNMSLFRNEWRKIFCCFFFPEKGAIFTDTSVRRNDLSVISS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5NUL3-2", "uniprot_id": "FFAR4_HUMAN", "id": "Q5NUL3-2", "name": "Free fatty acid receptor 4", "aln": "MSPECARAAGDAPLRSLEQANRTRFPFFSDVKGDHRLVLAAVETTVLVLIFAVSLLGNVCALVLVARRRRRGATACLVLNLFCADLLFISAIPLVLAVRWTEAWLLGPVACHLLFYVMTLSGSVTILTLAAVSLERMVCIVHLQRGVRGPGRRARAVLLALIWGYSAVAALPLCVFFRVVPQRLPGADQEISICTLIWPTIPGEISWDVSFVTLNFLVPGLVIVISYSKILQITKASRKRLTVSLAYSESHQIRVSQQDFRLFRTLFLLMVSFFIMWSPIIITILLILIQNFKQDLVIWPSLFFWVVAFTFANSALNPILYNMTLCRNEWKKIFCCFWFPEKGAILTDTSVKRNDLSIISG", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******:::* .* :: :*.***:***************:.:***** ***.*************.********..************ *******.************.*********:*********************:*:**: *****::*.***:******:******::**********.****.**** **. ******* ********************************:****************:********************************:******************************:* *.**:******:*******:*:**::*****:** ", "identical_positions": 305, "similar_positions": 44, "identity": "84.49%" }, { "cls_id": "homologset.agr.RGD:1308253", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JI08-1", "uniprot_id": "BIN3_MOUSE", "id": "Q9JI08-1", "name": "Bridging integrator 3", "aln": "MSWIPFKIGQPKK------QIVSKTVERDFEREYGKLQQLEEQTKRLQKDMKKSTDADLAMSKSAVKISQDLLSNPLCEQDQDFLHMVTALDTAMKRMDAFNQEKVNQIQ----KTVIEPLKKFSSIFPSLNMAVKRREQALQDYGRLQAKVEKYEEKEKTGPVLAKLHQAREELRPVREDFEAKNKQLLDEMPRFYGSRLDYFQPSFESLIRAQVIYYSEMHKIFGDLTQQLDQPGHSDEQR---ERENETKLSELRALSIVADD--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q68FW8-1", "uniprot_id": "BIN3_RAT", "id": "Q68FW8-1", "name": "Bridging integrator 3", "aln": "MSWIPFKIGQPKK------QIVSKTVERDFEREYGKLQQLEEQTKRLQKDMKKSTDADLAMSKSAVKISLDLLSNPLCEQDQDFLRMVTALDTAMKRMDAFNQEKVNQIQ----KTVIEPLKKFGSIFPSLNMAVKRREQALQDYGRLQAKVEKYEEKEKTGPVLAKLHQAREELRPVREDFEAKNKQLLDEMPRFYNSRLDYFQPSFESLIRAQVIYYSEMHKIFGDLTQQLDQPGHSDEHR---ERENETKLSELRALSIVADD--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NQY0-1", "uniprot_id": "BIN3_HUMAN", "id": "Q9NQY0-1", "name": "Bridging integrator 3", "aln": "MSWIPFKIGQPKK------QIVPKTVERDFEREYGKLQQLEEQTRRLQKDMKKSTDADLAMSKSAVKISLDLLSNPLCEQDQDLLNMVTALDTAMKRMDAFNQEKVNQIQ----KTVIEPLKKFGSVFPSLNMAVKRREQALQDYRRLQAKVEKYEEKEKTGPVLAKLHQAREELRPVREDFEAKNRQLLEEMPRFYGSRLDYFQPSFESLIRAQVVYYSEMHKIFGDLSHQLDQPGHSDEQR---ERENEAKLSELRALSIVADD--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P25343-1", "uniprot_id": "RV161_YEAST", "id": "P25343-1", "name": "Reduced viability upon starvation protein 161", "aln": "MSWEGFKKAINRAGHSVIIKNVDKTIDKEYDMEERRYKVLQRAGEALQKEAKGFLDSLRAVTASQTTIA-EVISNLYDDSKYVAGGGYNVGNYYLQCVQDFDSETVKQLDGPLRETVLDPITKFSTYFKEIEEAIKKRDHKKQDFDAAKAKVRRLVDKPAKD--ASKLPRAEKELSLAKDIFENLNNQLKTELPQLVSLRVPYFDPSFEALIKIQLRFCTDGYTRLAQIQQYLDQQSRDDYANGLLDTKIEELLGQMTSLDICALGIK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** ** . : : * **:::::: * : : *:. . ***: * *: *:: * ..*: :::** :.. .. : :: :: *:.*.*:*:: :**::*:.**.: * .:: *:*:*:: **: :***.: :* .. :** :*.:** .:: ** *.** *:*:: . *: **:****:**: *: : :: :. :.:: : *** .:.* . : : * *.:: :*.* * . ", "identical_positions": 70, "similar_positions": 100, "identity": "26.12%" }, { "cls_id": "homologset.agr.RGD:1308254", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P83714-1", "uniprot_id": "CTF2_MOUSE", "id": "P83714-1", "name": "Cardiotrophin-2", "aln": "MYCLLATPLCLLSLLLPPLSPAAPISPSEPIGQAYSLALYMQKNTSALLQTYLQHQGSPFSDPGFSAPELQLSTLPSAAVSFKTWHAMEDAERLSRAQGAFLALTQHLQLVGDDQSYLNPGSPILLAQLGAARLRAQGLLGNMAAIMTALGLPIPPEEDTLGFVPFGASAFERKCRGYIVTREYGHWTDRAVRDLALLKAKYSA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6R2R3-1", "uniprot_id": "Q6R2R3_RAT", "id": "Q6R2R3-1", "name": "Cardiotrophin-2", "aln": "MYCLLAAPLCLLSLLLSPLSPAAPISPSEPIGQAYSLALYMQKNTSALLQTYLQYQGSPFSDPGFSAPELQLSTLPSAAVSFKTWHAMGDAERLRQAQGAFLALTQHLQLVGDDQSDLNPGSPILLAQLGAARLRAQGLLGNMVTIMTALGLPVPPEEDTLGIVPFGASAFERKCRGYIVTREYGHWTDRAVRDLALLKAKYPA", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******:*********.*************************************:********************************* ***** :******************** **************************.:********:********:***************************************.*", "identical_positions": 192, "similar_positions": 9, "identity": "94.12%" }, { "cls_id": "homologset.agr.RGD:1308255", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D7R2-1", "uniprot_id": "PMEPA_MOUSE", "id": "Q9D7R2-1", "name": "Protein TMEPAI", "aln": "---------MSPARAT----------AQRSLFPSMEITELEFVQIVVIVVVMMVMVVMITCLLSHYKLSARSFISRHSQARRRDDG-LSSEGCLWPSESTVSG-GMPEPQVYAPPRPTDRLAVPPFIQRS---RFQPTYPYLQHEIALPPTISLSDGEEPPPYQGPCTLQLRDPEQQLELNRESVRAPPNRTIFDSDLIDSTMLGGPCPPSSNSGISATCYSSGGRMEGPPPTYSEVIGHYPGSSFQ-HQQSNGPSSLLEGTRLHHSHIAPLE-----NKEKEKQKGHPL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZNU8-1", "uniprot_id": "A0A8I5ZNU8_RAT", "id": "A0A8I5ZNU8-1", "name": "", "aln": "----MGVNGTAAAAAAGQPNVSCACNCQRSLFPSMEITELEFVQIVVIVVVMMVMVVMITCLLSHYKLSARSFISRHSQARRRDDGGLSSEGCLWPSESTVSG-GMPEPQVYAPPRPTDRLAVPPFVQRS---RFQPTYPYLQHEIALPPTISLSDGEEPPPYQGPCTLQLRDPEQQLELNRESVRAPPNRTIFDSDLIDSSMLGGPCPPSSNSGISATCYSSGGRMEGPPPTYSEVIGHYPGSSFQQHQQSNGQSSLLEGTRLHHPHIAPLE-----NKEKEKQKGHPL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q969W9-1", "uniprot_id": "PMEPA_HUMAN", "id": "Q969W9-1", "name": "Protein TMEPAI", "aln": "MHRLMGVN-STAAAAAGQPNVSCTCNCKRSLFQSMEITELEFVQIIIIVVVMMVMVVVITCLLSHYKLSARSFISRHSQGRRREDA-LSSEGCLWPSESTVSGNGIPEPQVYAPPRPTDRLAVPPFAQRERFHRFQPTYPYLQHEIDLPPTISLSDGEEPPPYQGPCTLQLRDPEQQLELNRESVRAPPNRTIFDSDLMDSARLGGPCPPSSNSGISATCYGSGGRMEGPPPTYSEVIGHYPGSSFQ-HQQSSGPPSLLEGTRLHHTHIAPLESAAIWSKEKDKQKGHPL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.* *: .:**** ************::**********:*********************.***:*. **************** *:******************** **. ************* ***************************************************:**: ******************.************************* ****.* .**********.****** .***:*******", "identical_positions": 232, "similar_positions": 21, "identity": "80.0%" }, { "cls_id": "homologset.agr.RGD:1308256", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LAD0-1", "uniprot_id": "A0ABK0LAD0_RAT", "id": "A0ABK0LAD0-1", "name": "Adenomatous polyposis coli protein 2", "aln": "MLVVGTSYIEEQHQVWLGTSHRSACGDRCPLPAKPLFLLARHGKGGQLQPGVRLDLRLYSSSKFGLDGMSRSPQNLLSALEWARGGFSPPFRWIHQGTERGQALQELKMASSVASYEQLVRQVEALKAENTHLRQELRDNSSHLSKLETETSGMKEVLKHLQGKLEQEARVLVSSGQTEVLEQLKALQTDISSLYNLKFHAPAL-------------GPEPAAQTPEGSPVHGPAPSKDSFG---------------ELSRATIRLLEELDQERCFLLSEIEKEEKEKLWYYSQLQGLSKRLDELPHVDT-FSMQMDLIRQQLEFEAQHIRSLMEERFGTSDEMVQRAQIRASRLEQIDKELLEAQDRVQQTEPQALLAVKP---VAVEE-QEAEVPTHPEDVTPQPGNSKVEVVFWLLSMLATRDQEDTARTLLAMSSSPESCVAMRRSGCLPLLLQILHGTEAGSVGRTGTPGAPGAKDARMRANAALHNIVFSQPDQGLARKEMRVLHVLEQIRAYCETCWDWLQARDSGTESG---TGDTPVPIEPQICQAACAVMKLSFDEEYRRAMNELGGLQAVAELLQVDYEMHK-MTQDPLNLALRRYAGMTLTNLTFGDV--ANKATLCARRGCMEAIVAQLASESEELHQVVSSILRNLSWRADINSKKVLREVGSMTALMECVLRASKESTLKSVLSALWNLSAHSTENKAAICQVDGALGFLVSTLTYRCQGNSLAVIESGGGILRNVSSLIATREDYRQVLRDHNCLQTLLQHLTSHSLTIVSNACGTLWNLSARSPRDQELLWDLGAVGMLRNLVHSKHKMIAMGSAAALRNLLAHRPAKYQAAAMAVSPGTC----VPSLYVRKQRALEAELDTRHLVHALGHLEKQ---GLPEAETTSKKPLPPLRHLDGLVQDYASDSGCFDDDDAP-SLAAAATTAEPASPAVMSMFLG-------GPFLQGQALARTPPARQ------GGLEAEKETGGEAAVAAKAKAK-LALAVARIDRLVEDISALHTSSDDSFSLSSGD---------PGQEAPREGRAQSCSPCRGTEG---GRREAGSRAHPLLRLKAAHTSLSNDSLNSGSTSDGYCTREHMTPCPLAVLTEHRDG-----PVCGQTRPSRLDLDLP-SRAELPARDTAA---------------------------------TDARVRTIKLSPTYQHVPLLDGAPGAGVRP-LVGLGTSPGTRKQAWIPADSLSKVPEKL-----VASPLPVTSKVLQKLVAQDGPMSLSRCSSLSSLSSTGHAV--PSQVENLDDSDSSLEELEEAGP-----GEAELDRAWRASG-----------STSLPVSIPAPQRGRSRGLG------VEDATPSSSSENCVQETPLVLSRCSSVSSLGSFESRSIASSIPSDP-CSALGSGTVSPSELPDSPGQTMPPSRSRTP---PAPPGQPEASQFS---------LQWESYVKRFLDIADCRERCQPPSELDAGSVRFTVEKPDENFSCASSLSALALHELYVQQDVELRLRPPACPERAVGGGGGHRRRDEATSRLDGPAPAGSRA--RSAADKELEALRECLGAAMPARLRKVASALVPGRR--------ALPVPVYMLVPAPARG-----------------DDSGTDSAEGTPVNFSSAASLSDETLQGPSRDKPARPGDRQKPTGRAAPARQT---------RGHRPKAAGAGAGKSTEHTRGANR------------NRAGLELPLSRPQSARSNRDGSCQTRTRGDGALQSLCLTTPTEEAVY-------CFY--DSDEEPPATAPPT--RRASAIPRALKREK----PAGRKET--PTRATQPATLP-------------VRAQPRLIVDETPPCYSLTSSASSLSEPEASEQP-----------------ACHPRVEE--------QGSKQDSSP--RAEEELLQRCISLAMPRRRTQVPSSRRRKPRAVRSDIRPTELPQKCREEVPGSDPASDLDSVEWQAIQEGANSIVTWLHQAAAKASLEASSESDSLLSLVSGLSASSTLQPSKLRKGRKPVAEAGGAWRPEKRGTTSTKGSGSPRFPSGPEKAKGTQKTMAGESAMLRGRTVIYTASPASRAQSKGISGPCSAPKKMGTSGTTQPETATKTPSPEQQRSR--SLHRPGKISELAALSHPPRSATPPARLTKTPSSSSSQTSPASQSLPRRSPLATPTGGPLPGPGGSPVP--------KSPARALLAKQHKTQKSPVRIPFMQRPAR--RVPPPLARPSPEPG---SRGRAGAEGTPGARGSRLGLVRVASTRSSGSESSDRSGFRRQLTFIKESPGLLRRRRSELSSADSTVSTSQTASPCRGRPALPAVFLCSSRCDELRAS---PRQ--PLAAQRVPQAKPGLAP-----------------RAPRRTSSESPSRLPVRATPG------RPETVKRYASLPHISVSRRPDSAVSVPTTQANATRRG----SDGEARPLPRVAAPG----TTWRRIKD----------EDVPHILRSTLPATALPLRGSS-PEDSPAGTP---------HRKTSDAVVQTEDVATSKTNSSTSPSLES-----RDPPQAPISGPVAPLG-----SDVDGPVLAKPPASAPFTHEGLSVVTGGFPTSRHGSPSRAARVPPFNYVPSPMVVATMTSDSAVEKAPVTSPASLLE---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z1K7-1", "uniprot_id": "APCL_MOUSE", "id": "Q9Z1K7-1", "name": "Adenomatous polyposis coli protein 2", "aln": "------------------------------------------------------------------------------------------------------------MTSSMASYEQLVRQVEALKAENTHLRQELRDNSSHLSKLETETSGMKEVLKHLQGKLEQEARVLVSSGQTEVLEQLKALQTDISSLYNLKFHAPAL-------------GPEPAARTPEGSPVHGSGPSKDSFG---------------ELSRATIRLLEELDQERCFLLSEIEKEEKEKLWYYSQLQGLSKRLDELPHVDT-FSMQMDLIRQQLEFEAQHIRSLMEERFGTSDEMVQRAQIRASRLEQIDKELLEAQDRVQQTEPQALLAVKP---VAVEEEQEAEVPTHPEDGTPQPGNSKVEVVFWLLSMLATRDQEDTARTLLAMSSSPESCVAMRRSGCLPLLLQILHGTEAGSVGRAGIPGAPGAKDARMRANAALHNIVFSQPDQGLARKEMRVLHVLEQIRAYCETCWDWLQARDSGTET--------PVPIEPQICQATCAVMKLSFDEEYRRAMNELGGLQAVAELLQVDYEMHK-MTRDPLNLALRRYAGMTLTNLTFGDV--ANKATLCARRGCMEAIVAQLGSESEELHQVVSSILRNLSWRADINSKKVLREVGSMTALMECVLRASKESTLKSVLSALWNLSAHSTENKAAICQVDGALGFLVSTLTYRCQGNSLAVIESGGGILRNVSSLIATREDYRQVLRDHNCLQTLLQHLTSHSLTIVSNACGTLWNLSARSPRDQELLWDLGAVGMLRNLVHSKHKMIAMGSAAALRNLLAHRPAKYQAAAMAVSPGTC----VPSLYVRKQRALEAELDTRHLVHALGHLEKQ---SLPEAETTSKKPLPPLRHLDGLVQDYASDSGCFDDDDAP-SLAAAATTAEPASPAVMSMFLG-------GPFLQGQALARTPPARQ------GGLEAEKEAGGEAAVAAKAKAK-LALAVARIDRLVEDISALHTSSDDSFSLSSGD---------PGQEAPREGRAQSCSPCRGTEG---GRREAGSRAHPLLRLKAAHTSLSNDSLNSGSTSDGYCTREHMTPCPLAALAEHRDD-----PVRGQTRPRRLDLDLP-SRAELPARDTAA---------------------------------TDARVRTIKLSPTYQHVPLLDGAAGAGVRP-LVGPGTSPGARKQAWIPADSLSKVPEKL-----VASPLPIASKVLQKLVAQDGPMSLSRCSSLSSLSSTGHAV--PSQAENLD-SDSSLEGLEEAGP-----GEAELGRAWRASG-----------STSLPVSIPAPQRGRSRGLG------VEDATPSSSSENCVQETPLVLSRCSSVSSLGSFESRSIASSIPSDP-CSGLGSGTVSPSELPDSPGQTMPPSRSKTP---PAPPGQPETSQFS---------LQWESYVKRFLDIADCRERCQPPSELDAGSVRFTVEKPDENFSCASSLSALALHELYVQQDVELRLRPPACPERAVGGGG-HRRRDEAASRLDGPAPAGSRA--RSATDKELEALRECLGAAMPARLRKVASALVPGRR--------SLPVPVYMLVPAPARG-----------------DDSGTDSAEGTPVNFSSAASLSDETLQGPSRDKPAGPGDRQKPTGRAAPARQT---------RSHRPKAAGAG--KSTEHTRGPCR------------NRAGLELPLSRPQSARSNRDSSCQTRTRGDGALQSLCLTTPTEEAVY-------CFY--DSDEEPPATAPPP--RRASAIPRALKREK----PAGRKET--PSRAAQPATLP-------------VRAQPRLIVDETPPCYSLTSSASSLSEPEAPEQP-----------------ANHARGPE--------QGSKQDSSPSPRAEEELLQRCISLAMPRRRTQVPGSRRRKPRALRSDIRPTEITQKCQEEVAGSDPASDLDSVEWQAIQEGANSIVTWLHQAAAKASLEASSESDSLLSLVSGVSAGSTLQPSKLRKGRKPAAEAGGAWRPEKRGTTSTKINGSPRLPNGPEKAKGTQKMMAGESTMLRGRTVIYSAGPASRTQSKGISGPCTTPKKTGTSGTTQPETVTKAPSPEQQRSR--SLHRPGKISELAALRHPPRSATPPARLAKTPSSSSSQTSPASQPLPRRSPLATPTGGPLPGPGGSLVP--------KSPARALLAKQHKTQKSPVRIPFMQRPAR--RVPPPLARPSPEPG---SRGRAGAEGTPGARGSRLGLVRMASARSSGSESSDRSGFRRQLTFIKESPGLLRRRRSELSSADSTASTSQAASPRRGRPALPAVFLCSSRCDELRVS---PRQ--PLAAQRSPQAKPGLAP-----------------LAPRRTSSESPSRLPVRASPG------RPETVKRYASLPHISVSRRSDSAVSVPTTQANATRRG----SDGEARPLPRVAPPG----TTWRRIKD----------EDVPHILRSTLPATALPLRVSS-PEDSPAGTP---------QRKTSDAVVQTEDVATSKTNSSTSPSLES-----RDPPQAPASGPVAPQG-----SDVDGPVLTKPPASAPFPHEGLSAVIAGFPTSRHGSPSRAARVPPFNYVPSPMAAATMASDSAVEKAPVSSPASLLE---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95996-1", "uniprot_id": "APCL_HUMAN", "id": "O95996-1", "name": "Adenomatous polyposis coli protein 2", "aln": "------------------------------------------------------------------------------------------------------------MASSVAPYEQLVRQVEALKAENSHLRQELRDNSSHLSKLETETSGMKEVLKHLQGKLEQEARVLVSSGQTEVLEQLKALQMDITSLYNLKFQPPTL-------------GPEPAARTPEGSPVHGSGPSKDSFG---------------ELSRATIRLLEELDRERCFLLNEIEKEEKEKLWYYSQLQGLSKRLDELPHVETQFSMQMDLIRQQLEFEAQHIRSLMEERFGTSDEMVQRAQIRASRLEQIDKELLEAQDRVQQTEPQALLAVKS---VPVDEDPETEVPTHPEDGTPQPGNSKVEVVFWLLSMLATRDQEDTARTLLAMSSSPESCVAMRRSGCLPLLLQILHGTEAAAGGRAGAPGAPGAKDARMRANAALHNIVFSQPDQGLARKEMRVLHVLEQIRAYCETCWDWLQARDGGPEGGG--AGSAPIPIEPQICQATCAVMKLSFDEEYRRAMNELGGLQAVAELLQVDYEMHK-MTRDPLNLALRRYAGMTLTNLTFGDV--ANKATLCARRGCMEAIVAQLASDSEELHQVVSSILRNLSWRADINSKKVLREAGSVTALVQCVLRATKESTLKSVLSALWNLSAHSTENKAAICQVDGALGFLVSTLTYKCQSNSLAIIESGGGILRNVSSLVATREDYRQVLRDHNCLQTLLQHLTSHSLTIVSNACGTLWNLSARSARDQELLWDLGAVGMLRNLVHSKHKMIAMGSAAALRNLLAHRPAKHQAAATAVSPGSC----VPSLYVRKQRALEAELDARHLAQALEHLEKQ---GPPAAEAATKKPLPPLRHLDGLAQDYASDSGCFDDDDAPSSLAAAAATGEPASPAALSLFLG-------SPFLQGQALARTPPTRR------GGKEAEKDTSGEAAVAAKAKAK-LALAVARIDQLVEDISALHTSSDDSFSLSSGD---------PGQEAPREGRAQSCSPCRGPEG---GRREAGSRAHPLLRLKAAHASLSNDSLNSGSASDGYCPREHMLPCPLAALASRRED-----PRCGQPRPSRLDLDLPGCQAEPPAREATS---------------------------------ADARVRTIKLSPTYQHVPLLEGASRAGAEP-LAGPGISPGARKQAWLPADHLSKVPEKL-----AAAPLSVASKALQKLAAQEGPLSLSRCSSLSSLSSAGRPG--PSEGGDLDDSDSSLEGLEEAGP-----SEAELDSTWRAPG-----------ATSLPVAIPAPRRNRGRGLG------VEDATPSSSSENYVQETPLVLSRCSSVSSLGSFESPSIASSIPSEP-CSGQGSGTISPSELPDSPGQTMPPSRSKTPPLAPAPQGPPEATQFS---------LQWESYVKRFLDIADCRERCRLPSELDAGSVRFTVEKPDENFSCASSLSALALHEHYVQQDVELRLLPSACPERGGGAGGAGLHFAGHRRREEGPAPTGSRP--RGAADQELELLRECLGAAVPARLRKVASALVPGRR--------ALPVPVYMLVPAPAPAQE---------------DDSCTDSAEGTPVNFSSAASLSDETLQGPPRDQPGGPAGRQRPTGRPTSARQA---------MGHRHKAGGAG--RSAEQSRGAGK------------NRAGLELPLGRPPSAPADKDGSKPGRTRGDGALQSLCLTTPTEEAVY-------CFYGNDSDEEPPAAAPTPTHRRTSAIPRAFTRER----PQGRKEAPAPSKAAPAAPPP-------------ARTQPSLIADETPPCYSLSSSASSLSEPEPSEPP-----------------AVHPRGREPAVTKDPGPGGGRDSSPSPRAAEELLQRCISSALPRRRPPVSGLRRRKPRATRLDERPAEGSRERGEEAAGSDRASDLDSVEWRAIQEGANSIVTWLHQAAA-ATREASSESDSILSFVSGLSVGSTLQPPKHRKGRQAEGEMGSARRPEKRGAASVKTSGSPRSPAGPEKPRGTQKTTPGVPAVLRGRTVIYVPSPAPRAQPKGTPGPRATPRKVAPPCLAQPAAPAKVPSPGQQRSR--SLHRPAKTSELATLSQPPRSATPPARLAKTPSSSSSQTSPASQPLPRKRPPVTQAAGALPGPGASPVP--------KTPARTLLAKQHKTQRSPVRIPFMQRPAR--RGPPPLARAVPEPG---PRGRAGTEAGPGARGGRLGLVRVASALSSGSESSDRSGFRRQLTFIKESPG-LRRRRSELSSAESAASAPQGASPRRGRPALPAVFLCSSRCEELRAA---PRQGPAPARQRPPAARPSPGE-----------------RPARRTTSESPSRLPVRAPAA------RPETVKRYASLPHISVARRPDGAVPAAPASADAARRS----SDGEPRPLPRVAAPG----TTWRRIRD----------EDVPHILRSTLPATALPLRGST-PEDAPAGPP---------PRKTSDAVVQTEEVAAPKTNSSTSPSLET-----REPPGAPAGGQLSLLG-----SDVDGPSLAKAPISAPFVHEGLGVAVGGFPASRHGSPSRSARVPPFNYVPSPMVVAATT-DSAAEKAPATASATLLE---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QMA5-1", "uniprot_id": "A0A8M9QMA5_DANRE", "id": "A0A8M9QMA5-1", "name": "Adenomatous polyposis coli protein 2", "aln": "-----------------------------------------------------------------------------------------------------------MMSFPTASYDQLVRQVEDLRKENSHLRRELQDNSHHLSKLENETSDMKEVLRQLQSKLEQEAGTLASSGRTDVLDQLKELHMDLTNYYELKYQPHNLRVFPELMAGQVGEGEERLSISRSRSPVCQSSRQSSSASGEGTAVHPGLPHQVAGEGRITAQHLEDLCKERTMLLSEIEKEEKERRWYYSQLQGLSQRLAELPRLDT-FSMQVDFIRQQLEFEAQQLRSVMEERFGTSDEMVQRTQIRVARLEQLEKELHDAQSSRGPQEKSALPETQSTECLPKACVPDMDTGNAGTLDAPGEAGSKVEMVFWLLSMLASRDREEMSRTLLAMSSSQESCIAMRKSGCVPLLVQILHEGGTGEAAGTGCY----SREARSRASAALHNIVYSQPDEGQARREMRVLHVLEQIRSHCENGWDWIENHLSTPSPGGSKTTEIPEPVDPQICQALCAIMKLSFEEEYRRAMNELGGLQAIAELMQLDQELYG-MHNEPINMALRRYAGMAVTNLTYGDV--VNKATLCSKKNCLQAIVAQLASDSEELQQVVSSILRNLSWRADINSKRALRDVGSVSGLMTCALQATKESTLKSVLSALWNLSAHSTENKVAICSVDGALGFLVSTLTYRCQTNSLAIIESGGGILRNVSSLIATRDDYRQILRDHNCLQTLLQHLRSHSLTIVSNACGTLWNLSARSPKDQELLWDLGAVSMLRNLINSKHKMIAMGSAAALRNLLTNRPLKYKDAA-VISPGSC----MPSLYMRKQKALEAELDAKHLAETFDTLEKQ---SFKHANIN-----KPLRHIESLAKDYASDSGCFDDDEAP----NVSTSLDTGTFSMLSMFLNN------SNFLNTQLRKREGEPEQDIETFQTDIKRSQPPDDEVTVAAEKLAKKITNTVAKIDKLVDDIT-MHTSSEDSFSLSSEDHFL---DWNYGPDELHEARAISCSPCPLSDSSTFSPKERLSRAHAFMRLKTTNSSLSNDSLNSGSISDGYCGSQDQTHPSARPTEQRRPNKLDLKVAHEEPLTNGVHISRVMCQNEIPERDFEANKDAILPDSGSTDTEKSQEPFISTPATVSTKVSSETSIPTVKLSPSYQHVPLIQSVAKFGVAKTAINVQAAQAMRRQAWVPAVMTGGSISKFSPICSARSPTIGQLETPQKYSVENTPICFSRCSSLSSLSSGDGALDGQSQTENELESDSSLEIIEVEDVNVERKDEEDENETLDDLSDSQLLVTDQKISSSDPIEISGTIKNEKRFLRGVSPVILEDRTPSSSSDNYIHETPLVMSRCSSVSSLGSFESPSIASSIQSDP-CSEMISGTVSPSDLPDSPGQTMPPSRSKTP--CCPESGGADAQNLSGV------GSQWESSLRKFMEIADFKERFNLPQDLDT-MIYFTVEKPIENFSCASSLSALPLHEHYVQKDVELKLTPLLNQQD-----------NDPEESEKEEDMEDQYS--EGNSDDDIEILKECINSAMPSRFKKVRSTVIPSLSNQVINMQARKSVPVYMVLQNKNNQMCTGQKLGMSSKEIYHDDSSYTDSAEGTPINFSSTTSLSDETLQYPARTKGMKDWRRNKETQELVDIEAKRIEDLRMFSRFHKPTKIACQSHLVTNQLNKTIRRMVPTQRLLIQSKEMAAKMTQQRIQSQSPVRQIQKQGQNLSRSMPQLDFPMRKQSTEVYQNQK---TCYLSHVQENTLSLKSRRHPSSTEGICHKMERHDGQMNRTGRKQQYDSSNIIRNANIQDQVNSYQSRQNGFHRIKQNLILEEAPPCYSLSSSLSSLSDAEFEEHENPQHTWIKNRHNIMSNLQCHPKSQKDLN---QFEENSSPSSVSMDSEDDLLIKCITSAMPQHKKRQAARKRK--AEKKHKQKATLLDNDLDSDEMASDKDSDLNSVEWRAIQEGANTIITKLQASKS---QEPSSESESVLSFMS----GSSFTPKEKK-----------VYKDDKK--ANKPLDFAPRKP------------VPNFPVVFRGRTVIYTPKKETTLSQR------PPPKKVSP-----KADAPKNPNLAQHRSR--SLHRLGQPMESTQLSLPKRSSTPPARIPKSSSSGSSQSSTPSRQPQKKVTSQPPIKGTEKVASAPSSPPDRRGRNSNIDQNSKSPIDRKTQKSPVRIPFMQNPSRQTRNISPLVTNQPTSI---SRQNTQMSGKRILPANRIDLVRMTSAHSSSGES-DQNGFLRQLTFIKETSKVSRYDASSRS-----VPASQHASPRRSGPGAPAVFLCSSRCQELKEAVQGPKRMPVTHGQRQVQEQGVLRQGMALSRATSIDRDVTVNRPARRTSSESPCRASKRNTPCPKPREKRDDTFKRYSSSPSINVLSRVTSRSSLRSSSSDSSGRAK---SERNVNQKQQRAGLRNADKVTWRRIRD----------EDVPQILKSTLPPTALPLLPSPGTKQMPPPLPGKLPTITLASRKTSDATVQTEDYSANKTNSSTSPTIDKGLSITEETAKIALPKKIVVFGNTLQDGDSDGSLKNYSTASTATFQSTESTHSSGVGHFRQSSPSKAVRVTPFNYIPSPMVGCSPQTQGQATTMFEKTVDKHEV---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VAS9-1", "uniprot_id": "Q9VAS9_DROME", "id": "Q9VAS9-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------MLEPTLTPDLEEGIAELSLEDVDVDSVPERKPHFLDYDAVPPPDYEEGFGASSGEQLKMDKKYERDGEVSDYELAAS-------------GYTKKEFTQDDNTLHFTQSAVGLGSG------------AVGKKPAAKHFLDENPIPPDYMLAQELREMREHRSLDRNFERQSAQQQQLDELPP-------------------------RNGGGSPASAGRPSRSKEPSYTLSRFLDGDAPAPAPRLPKGAAWTTS------------FDERYTSSAVEATLGSKVECVYSLLSMLGSNDPLEMAKKFLELSGNAQSCATLRRSGCMPLLVQMMHAPDNDQ-------------EVRKCAGQALHNVVHSHPDEKAGRREAKVLRLLDQIVDYCSFLKTLLQSGGEAIADDS----------DRHPLAAISSLMKVSFDEEHRHAMCELGALHAIPNLVHLDHAVHGPKPEDQCCNSLRRYALMALTNLTFGDE--NNKALLCGQKQFMEALVAQLDSAPDDLLQVTASVLRNLSWRADSNMKAVLNEIGTVTALALAAMRNRSENTLKAILSALWNLSAHCSTNKAEFCAVDGALAFLVGMLSYEGPSKTLKIIENAGGILRNVSSHIAVCEPYRQILRQHNCLAILLQQLKSESLTVVSNSCGTLWNLSARSAEDQKFLWDNGAVPMLRSLIHSKHAMISEGSSSALKNLLNFRPAVQNHHQLDPIARSMGLKALPTLEARKAKALQQELGERHTAETCDNLDTGGKLDKERASSSSRRHPAPRLTRSAMLTKSESRDSVYSAKSDCAYDHLIRSASASDAHRKVKPKITDFDLEMEQDTEATEEQPIDYSVKYSENATKTSTYQETDLDQPTDFSLRYAENQIESDLDISGPAGGQKSTITPPAETVPEKSEGQEILLILDDSVKCYQTEDTPYVISNAASVTDLRVAAKADAEAEVKPEVREVTSKEGAPKKLPKLSQCGSGSYTPEKPINYCEEGTPGYFSRYDSLSSLDESGKANQAIVGTDADIKPKLEKQEEQ---------------------------------ESQPAEQVLTKPPTQANSALETPLMFSRRSSMDSLVHDPDVDVANCDDKSSVVSDFSRLA----SGVISPSEIPDSPTQSMPQSPRRNSVAGSGQNVDSPPVVIPASLQPLRSVFEDDLSSFNVEHTP-----AQFSTATSLSNLS----------IVDDEKAPASVAEEDNEDELLLANCINMGMQRKPTEAVKSTVVNSEVDVAEETIRSYCTEDTPALLSKVPSNTNLSVISMSSTDPKDATAGQAQMYAHQLSDDVSSNASDCGGASGHLLQQCIRDGMKKPLGEATSDPIAMLRRGGNELPGYLPSADEMNKFLVEDSPCNFSVVSGLSNLTVGSSLVGPAVQL--KETEPSSADQNPEMKAKPGKQEQVRRPPHWQDDSLSSLSIDSEDDTNLLSQAIAAGCNRPKSNLGFSSNGKRS-------SSLSSSQPIAINAATSASSL------------NSAMTVRKSQQQE--SYSSVDSSDSNDN--QSKSLFELCILKGMYKTKEPGARAQ---------QMQEQPIVGSSSVQSNPSLKQFDS----------LPVQLPSSGQVKRQRHHHHHHHHRERERERKDEKLLQECINTGISKKINAVPKNVLATSAAALEPCHPMAATTSASALSTAAPDVEQKAHATSNPQQQSSTHPSSHILPNPIDAIATVTDTVRSPAAPNQGNGNASQNGLETATGSKDLDSEDRSSDESNQSFIMETMVRLDSALNETCISGASEKHKDPDLMLKSVERLTMEFVTSAEQLRSSSHNHSSSNSHKNNSSNNTWNESTCPNDVSFPSVSQTAPVLASLSLDEDATEARSLHELIEITPTNEQQPESLEGETDTLVNGHADSYSGSSGGLNFQLGGQVQNAGVRLEPQRLLFNGTSASIMTNSTMIAFEARALAENLLQPAATDDDTTEMTFSLNSLDLDNIRPPSGMESLNSCYQDHSQPSSLRQAMPSKSPRFARKMFPANLVARRALGHLAGSAESVNSSCNLLDNIKPPSLMDELLDSMISVDSIQSEVADGEQDCSMATTISVSNYETAACDDQTMTVLQSCFDEDEDATMNDYSSAESTPKHGSTPSPNRRSLTPKDKRRLTKDRFKTYTIATSCEMEAPEANETLQIEIVEAAVPVATPSPRANGRRRGSAERYKTQLIECPLALIQPQPDDCPSEQLSSIRAMMQQFTFITDINIGHSQETCESTDHPEDAGESPECDQNSETESCDGQEPDQLPPPPSIVDLRTSVVKPTTLEPATAVKLVRGRKKPAYVSPYSMQSQRNSNNAAPSKKKTLSPTIAKRSLVPGGSGVRLPAKKKPTPPPEPAPARLERQGTFVKDEPTNSNVQVPVVETKPAQTSPTHRASKLPTKKGTASGGSPSKAGSPKRIPLAPARRMTPQRANTSLRLAAGKSHAASRVVSG-----RVSSTTPPSRSNSNLNGSSAAAAAAAKINHAQSRIANIWKRVDEAKTKQSSSNLRTQKTKSSNMLNANGTKPTLLRSSTFDNTPSTAGGVKSKLPVVGARK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9Y1T2-1", "uniprot_id": "Q9Y1T2_DROME", "id": "Q9Y1T2-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTLNESDATR-------------------LELTRNFLELSRNPETCTALRSSDCIQLLVQILHANDEGLS------------TAKKYASQALHNIVHNNPEEKERQREVKMLRLLDQILDYCNFLHTQLQSGGEAIADDE----------DRHPLAAMKLLMKASFDEEHRQTMCELGALKAIPNLVHLDHAVHGPAAGREQCNALRSYGLMALTNLTFGDENVHNKSYLCGQRQFMEVVIAQLNTAPDELLQVLAGVLRNLSWRADKHMKTIFNELGTVTSLARAAMQNKNENTLKAILSALWNLSAHCSTNKAEFCAVDGALAFLVGMLSYEGPSKTLKIIENAGGILRNVSSHIAVCEPYRQILRRYNCLAILLQQLKSESLTVVSNSCGTLWNLSARCPEDQQYLIDHNAIPLLRALISSKNSMIAEGSASALKNLVNFR----ATQELMPNGDGG------SLPLDKEAGHGGTLPRRFSSLRLSSNPTG-SLKKVRPSTVS--------TTGFLNRKCESRESIYSGKSDST-KYSTKSEGAKNPFEIVTP---------------TEEQPIDYSMKYMEHKPNSSKTFEIDLDQPTDFSARYKE---------------RRSAQTAQPELKSETN----------------EIRSKELQLTKSSSATELRNSPGLVAVSAAKQKIATETETE-----------------TAERPINYCEEGTPGSFSRFDSLNSLTE--KPEKCMP----------PKTPTK---------------------------------TAVLPVHVDGNTPQNIDSALETPLMFSRRSSMDSLVGD--DETVACEDNGSVISEYSRMQ----SGVISPSELPDSPTQSMPQSPRRDRKVSTQNNLDTP-------EQKPSTVFEDKLNRFHVEHTP-----AAFSCATSLSNLS----------MMDDSNANAIRGQRGND-----------------------------INGNGDAPRSYCTEDTTAVLSKAPSNSDLSILSI----PNDLNANEAQPVPAPRADVTGMDTR-----------------------MPAEDAISKMRCGGNALPSYLPVSDEMSKYYVEDSPCTFSVISGLSHLTVGSAKAGPVLKLPMRTAEEAQAPKLPPRRSAVQGDAEPRLPPKK-SDSLSSLSMDSDDDCNLLSQAIAAGSCRPQP-----SGASTS-------SSLAN-------ASTSTLCR------------ENGQSKKQVEHGDKPNYSSDDSLDDDDDDARSKSLFEQCILSGMHKSND----------------------------------------------------ALESEGEPPGQRQEISARDRFVSNQVRQIESMLAGRQH------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ::.:* :* . ::* ::* *.*: **:*::* .: *. ****:*..:*:: ::* ::*::*:** :*. :: : : * :** **:**:*::* ***.*:*:.:*:::* :: :** *. *::****:** **: **.:: ::.::*** : .::* ** :.:********* : * :.: *:::.* ..:: .*.***::**********.: **. :* *****.***. *:*. ::* :**..********* :*. : ***:** :*** ***:* *.***:***:**********...**: * * .*: :** *: **: **: **::**:**: * :* * . * :. . .. : . * .. :. .. : . :. : . . . . . .: . : . .: . . .. ... .: : .: : : : . : : ... : . :: . . .:: . : * .: ..:.: : .*. . : . . ... : .: * : :: :: *. *:. * *.: . .* . : . : : : : **.. .** *.** *.: . . ::* . .. . ::.: : * :.: :. . : . . .:** * ..: .: . . . :. : ", "identical_positions": 184, "similar_positions": 270, "identity": "6.73%" }, { "cls_id": "homologset.agr.RGD:1308257", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BXL9-1", "uniprot_id": "IFFO1_MOUSE", "id": "Q8BXL9-1", "name": "Non-homologous end joining factor IFFO1", "aln": "------------------------------------------------------------------------------------------------------------------------------------MNPLFGPNLFLLQQEQQGLAGPLGDPLGGDHFAGGGDLASAPLASAGPSAYSPPGPGPAPPAAMALRNDLGSNINVLKTLNLRFRCFLAKVHELERRNRLLEKQLQQALEEGKQGRRGLARRDQAVQTGFISPIRPLGLPLSSRPAAVCPPSARVLGSPSRSPAGPLASSAACHTSS--STSTSTAFSSSTRFMPGTIWSFSHARRLGPGLEPTLVQGPGLSWVHPDGVGVQIDTITPEIRALYNVLAKVKRERDEYKRRWEEEYTVRIQLQERVTELQEEAQEADACQEELAMKVEQLKAELVVFKGLMSNNLTELDTKIQEKAMKVDMDICRRIDITAKLCDLAQQRNCEDMIQMFQKKLVPSMGGRKRERKAAVEEDTSLSESDGPRQPEGAEEESTALSINEEMQRMLSQLREYDFEDDCDSLTWEETEETLLLWEDFSGYAMAAAEAQGEQ-EDSLEKVIKDTESLFKTREKEYQETIDQIELELATAKNDMNRHLHEYMEMCSMKRGLDVQMETCRRLITQSGDRKSPAFTAVPLSDPPPPPSETEDSDRDVSSDSSMR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6ACM7-1", "uniprot_id": "A0A8I6ACM7_RAT", "id": "A0A8I6ACM7-1", "name": "", "aln": "MNFSFHFLVSKEKAIELDPRYRGEEAVGKAASKVPEVLCLRSYSQDLRRWFPRKGESGSSNVDSTHRTSDPGKVQSKSSNEGFSLASSAPSFMTFGLLPGHLIGHSYSTNISLARLLTLCCTGLPLPAEGAAMNPLFGPNLFLLQQEQQGLAGPLGDPLGGDHFAGGGDLPSASLASAGPSAYSPPGPGSAPPAAMALRNDLGSNINVLKTLNLRFRCFLAKVHELERRNRLLEKQLQQALEEGKQGRRGLARRDQAVQTGFISPIRPLGLPLSSRPAAVCPPSARVLGSPARSPAGPLASSAACHSSSSTSTSTSTAFSSSTRFMPGTIWSFSHARRIGPGLEPTLVQGPGLSWVHPDGVGVQIDTITPEIRALYNVLAKVKRERDEYKRRWEEEYTVRIQLQERVTELQEEAQEADACQEELAMKVEQLKAELVVFKGLMSNNLTELDTKIQEKAMKVDMDICRRIDITAKLCDLAQQRNCEDVIQMFQ---VPSMGGRKRERKAAVEEDTSLSESDGPRQPEGDEEESTALSINEEMQRMLSQLREYDFEDDCDSLTWEETEETLLLWEDFSGYAMAAAEAQGEQQEDSLEKVIKDTESLFKTREKEYQETIDQIELELATAKSDMNRHLHEYMEMCSMKRGLDVQMETCRRLITQSGDRKSPAFTAVPLSDPPPPPSETEDSDRDVSSDSSMR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q0D2I5-1", "uniprot_id": "IFFO1_HUMAN", "id": "Q0D2I5-1", "name": "Non-homologous end joining factor IFFO1", "aln": "------------------------------------------------------------------------------------------------------------------------------------MNPLFGPNLFLLQQEQQGLAGPLGDSLGGDHFAGGGDLPPAPLSPAGPAAYSPPGPGPAPPAAMALRNDLGSNINVLKTLNLRFRCFLAKVHELERRNRLLEKQLQQALEEGKQGRRGLGRRDQAVQTGFVSPIRPLGLQLGARPAAVCSPSARVLGSPARSPAGPLAPSAASLSSS--STSTSTTYSSSARFMPGTIWSFSHARRLGPGLEPTLVQGPGLSWVHPDGVGVQIDTITPEIRALYNVLAKVKRERDEYKRRWEEEYTVRIQLQDRVNELQEEAQEADACQEELALKVEQLKAELVVFKGLMSNNLSELDTKIQEKAMKVDMDICRRIDITAKLCDVAQQRNCEDMIQMFQ---VPSMGGRKRERKAAVEEDTSLSESEGPRQPDGDEEESTALSINEEMQRMLNQLREYDFEDDCDSLTWEETEETLLLWEDFSGYAMAAAEAQGEQ-EDSLEKVIKDTESLFKTREKEYQETIDQIELELATAKNDMNRHLHEYMEMCSMKRGLDVQMETCRRLITQSGDRKSPAFTAVPLSDPPPPPSEAEDSDRDVSSDSSMR", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *************************.************..*.*:.***:********.*************************************************************.**********:******** *.:******.*********:********.***. :** ******::***:***************:*****************************************************************:**.*****************:********************:*****************************:********:***** ************************:*****:* *****************.******************************************* *************************************.*******************************************************:**************", "identical_positions": 524, "similar_positions": 32, "identity": "75.18%" }, { "cls_id": "homologset.agr.RGD:1308258", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BJQ4-1", "uniprot_id": "TCAM2_MOUSE", "id": "Q8BJQ4-1", "name": "TIR domain-containing adapter molecule 2", "aln": "MGVGKSKLDKCP--LSWHKKDS-------VDADQDGHESDSKNSEEACLRGFVEQSSGSEPPTGEQDQPE-AKGAGPEEQDEEEFLKFVILHAEDDTDEALRVQDLLQNDFGIRPGIVFAEMPCGRLHLQNLDDAVNGSAWTILLLTENFLRDTWCNFQFYTSLMNSVSRQHKYNSVIPMRPLNSPLPRERTPLALQTINALEEESQGFSTQVERIFRESVFERQQSIWKETRSVSQKQFIA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86XR7-1", "uniprot_id": "TCAM2_HUMAN", "id": "Q86XR7-1", "name": "TIR domain-containing adapter molecule 2", "aln": "MGIGKSKINSCPLSLSWGKRHS-------VDTSPGYHESDSKKSEDLSLCNVAEHSNTTEGPTGKQEGAQSVEEMFEEEAEEEVFLKFVILHAEDDTDEALRVQNLLQDDFGIKPGIIFAEMPCGRQHLQNLDDAVNGSAWTILLLTENFLRDTWCNFQFYTSLMNSVNRQHKYNSVIPMRPLNNPLPRERTPFALQTINALEEESRGFPTQVERIFQESVYKTQQTIWKETRNMVQRQFIA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZTX0-1", "uniprot_id": "TMED7_RAT", "id": "D3ZTX0-1", "name": "Transmembrane emp24 domain-containing protein 7", "aln": "MPRPRSATCWAAAAGRWSCRLLALLLLLLLPGPSGGSEITFELPDNAKQCFYEDITQGTKCTLEFQVITG---GHYDVDCRLEDPDGKVLYKEMKKQYDSFTFTASKNGTYKFCFSNEFSTFTHKTVYFD-----FQVGEDPPLFPSENRVSALTQMESACVSIHEALKSVIDYQTHFRLREAQGRSRAEDLNTRVAYWSVGEALILLVVSIGQVFLLKSFFSDKRTTTTRVGS--------", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :* .. * : : . * : .:: : :. :: . * . : * *: : .. ::: . :. : : . *: :. ::: .: . . *: :** : . .*: :::. .*:: : :* :. * : .. * . : : :: :*.:. ::: ... . ", "identical_positions": 17, "similar_positions": 77, "identity": "7.02%" }, { "cls_id": "homologset.agr.RGD:1308259", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZQM6-1", "uniprot_id": "D3ZQM6_RAT", "id": "D3ZQM6-1", "name": "", "aln": "MGKTSQRKQCDCENP--SKPCLSTSIPLRMSNYTFKRPVTKITSHLGNEVRYYQWEETLEKPEQACWQKRLQGLQAYSSAGEILSTSDLSKALKDLTPRDTDAASSIIQANSMDP-RPLSTLGSSSHLAKMIPEAGP---QILCKEFLVTEEDISIQERKVKIARERLAVALIAHKLANETEKVRGS--RKAKV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D9H3-1", "uniprot_id": "MB3L1_MOUSE", "id": "Q9D9H3-1", "name": "Methyl-CpG-binding domain protein 3-like 1", "aln": "MGKTSQRKQCDCENP--SKPCLSTSIPLRMSSYTFKRPVTKITSHLGNEVRYYQWEETLEKPEQACWQKRLQGLQAYSSAGELLSTSDLAKTLKDLTSTDTVASASDTQATSIDI-TSVPTLESSSHLANMIPEAGP---QILCKEFLVTEQDIINQERKVKIARERLAVALIAHKLASEMETVRGS--RKANL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WWY6-1", "uniprot_id": "MB3L1_HUMAN", "id": "Q8WWY6-1", "name": "Methyl-CpG-binding domain protein 3-like 1", "aln": "MAKSSQRKQRDCVNQCKSKPGLSTSIPLRMSSYTFKRPVTRITPHPGNEVRYHQWEESLEKPQQVCWQRRLQGLQAYSSAGELSSTLDLANTLQKLVPSYTGGSLLEDLASGLEHSCPMPHLACSSDAVEIIPAEGVGISQLLCKQFLVTEEDIRKQEGKVKTVRERLAIALIADGLANEAEKVRDQEGRPEKR", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.*:***** ** * *** **********.********:**.* ******:****:****:*.***:*************: ** **:::*:.*.. * .: *..:: .:. * .**. .::** * *:***:*****:** ** *** .*****:****. **.* *.**.. * : ", "identical_positions": 111, "similar_positions": 43, "identity": "57.22%" }, { "cls_id": "homologset.agr.RGD:1308260", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BH79-1", "uniprot_id": "ANO10_MOUSE", "id": "Q8BH79-1", "name": "Anoctamin-10", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------MRVTLSTLDTCESSFTPLVVIELAQDVKDETKEWLKNRIIAKKKDGGAQLLFRPLLNKYEKETLENQ----NLYLVGASNVRLLLGAEAVGLVKECTDAAMRAFTYG----------TRHNFKGFHDNNNDFLTMAECQFIIKHELENLRARDEKMIPGYPQAKLYPGKSLMRRLLT------------------SGIVTQVFPLHDTEALKKLE-DTWYTRFALKYQPIDSIRSYFGETIALYFGFLEYFTFALIPMAIIGLPYY--------------------------LFVWEDYDKYVIFASFNLIWSTVILEVWKRGCANMTYRWGTLVMKRQFEEPR-------------PGFHGVLGINSVTGREEPLYSSYKRQLRIY----LVSLPFVCLCLYFSLYVMMIYFDMEDWALSLHEDSGSEWTSLLLYVPSIVYAVVIEIMNRLYRYAAEFLTSWENHRLESAYQNHLVLKVLVFNFLNCFASLFYIAFVLKDMKLLRQSLATLLITSQILN----QVVESLLPYWLQ-----------RKYCARVKRK----VQALKSEVDTTLYEQVLLEKEMGTYLGTFDDYLELFLQFGYVSLFSCVYP-LAAAFAVLNNFTEVNSDALKMCRVFKRPFAEPSAS----------IGVWQLAFETMSVISVVTN-----------------------------------------------CALIGMSPQVNAVFPESK-TDLVLIVVAVEHALLA---LKFILAFAIPDKPRHIQQKLARLEFESLEALKQQQMKLVAENLKEEYQEDGKEAT-------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LE79-1", "uniprot_id": "A0ABK0LE79_RAT", "id": "A0ABK0LE79-1", "name": "Anoctamin", "aln": "MFSWFLKEKETAERKHWSGSPGSRACRRMPPSRTESSLSALELCGSQGLCHGYPVATSQSCPWETETSSQPYGMELSRLLPLRAPVIIRVGKPHPEAPGRAILSPDSQIEEEEEEAEEEEKKEEERRRRKRKKKKRKKRRKKKRRLLRSKRLSLSKMKGILSTVDTCESSFTPLVVIELAQDVKEETKEWLKSRIISPKKDGGAQLLFRPLLNKYEKETLENQ----NLYLVGASNIRLLLGAEAVGLVKECTDGAMRAFTYR----------TRHNFKGFHGNNDDFLTMAECQFIIKHELENLRARDEKMIPGYPQAKLYPGKSLMRRLLT------------------SGIVTQVFPLHDTEALKKLE-DTWYTRFALKYQPIDSIRGYFGETIALYFGFLEYFTFALIPMAVIGLPYY--------------------------LFVWEDYDKYVIFASFNLIWSTVILEVWKRGCANMTYRWGTLVMKRQFEEPR-------------PGFHGVLGINSVTGREEPVYSSYKRQLRTY----LVSLPFVCLCLYFSLYVMMIYFDMEDWALSLHEDSGSEWTSLLLYVPSIVYAIVIEIMNRLYRYAAEFLTSWENHRLESAYQNHLVLKVLVFNFLNCFASLFYIAFVLKDMKLLRQSLATLLITSQILN----QVVESLLPYWLQ-----------RKYCARVKRK----VRALKSDVDTTLYEQVLLEKEMGTYLGTFDDYLELFLQFGYVSLFSCVYP-LAAAFAVLNNFTEVNSDALKMCRVFKRPFSEPSAS----------IGVWQLAFETMSVISVVTN-----------------------------------------------CALIGMSPQVNAVFPESK-TDLVLIVVAVEHALLA---LKFILAFAIPDKPRHIQMKLARLEFESLEALKQQQMKLVAESLKEESQEEEKEAAACRMPATLPQPELRNNCITPGQGGDASLS--------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NW15-1", "uniprot_id": "ANO10_HUMAN", "id": "Q9NW15-1", "name": "Anoctamin-10", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------MKVTLSALDTSESSFTPLVVIELAQDVKEETKEWLKNRIIAKKKDGGAQLLFRPLLNKYEQETLENQ----NLYLVGASKIRMLLGAEAVGLVKECNDNTMRAFTYR----------TRQNFKGFDDNNDDFLTMAECQFIIKHELENLRAKDEKMIPGYPQAKLYPGKSLLRRLLT------------------SGIVIQVFPLHDSEALKKLE-DTWYTRFALKYQPIDSIRGYFGETIALYFGFLEYFTFALIPMAVIGLPYY--------------------------LFVWEDYDKYVIFASFNLIWSTVILELWKRGCANMTYRWGTLLMKRKFEEPR-------------PGFHGVLGINSITGKEEPLYPSYKRQLRIY----LVSLPFVCLCLYFSLYVMMIYFDMEVWALGLHENSGSEWTSVLLYVPSIIYAIVIEIMNRLYRYAAEFLTSWENHRLESAYQNHLILKVLVFNFLNCFASLFYIAFVLKDMKLLRQSLATLLITSQILN----QIMESFLPYWLQ-----------RKHGVRVKRK----VQALKADIDATLYEQVILEKEMGTYLGTFDDYLELFLQFGYVSLFSCVYP-LAAAFAVLNNFTEVNSDALKMCRVFKRPFSEPSAN----------IGVWQLAFETMSVISVVTN-----------------------------------------------CALIGMSPQVNAVFPESK-ADLILIVVAVEHALLA---LKFILAFAIPDKPRHIQMKLARLEFESLEALKQQQMKLVTENLKEEPMESGKEKAT------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q4V8U5-1", "uniprot_id": "ANO10_DANRE", "id": "Q4V8U5-1", "name": "Anoctamin-10", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------MQLGLSVSDSDASPFTPLAVLELAHDTKAEAIAWLLNRIRDKQRNGGAELLVDQLLFPAQDGQKPNP----NVFVVGSTLQRLLSGAEDVGLFKEFQDGTMRGFTYA----------NRESFKDFEGDGEGFLGDAECQYIVKHELDTLRAKNEEYIPGYPKYKLYPGKSIVRRLQS------------------KGVLVQYFPLHNKEDLKRLS-FSWYKKIKLSFQPLDDIRSYFGEGLGLYFGFLEYFTFALIPMALIGIPYY--------------------------LFDWEDYDKYVLFAVFNLVWSTVFLEVWKRCSATLAYSWGTLGRKKAFEEPR-------------AGFHGPLGLNPVTGREEPIYPSSKRHLRIY----LVSVPFVLLCLYLSFYVMMVYFDMEFWAISIYHENPNFATSVLLFVPSIIYAVVIEIMNLLYRYAAEFLTDWENHRLESSFQNHLVPKVLVFNFVNCFASLFYIAFVMQDMVLLRQSLATLLITSQILN----QVMEAFLPYWLQ-----------RRRNKRVYKR----MRRLMGDKELPLLEQIQLETEMNTYLGTFDDYLEQFLLFGYVSLFSCVHP-LAAVLVVLNNITEVYSDAFKMCHVFKRPFSEPAAN----------IGVWQLAFETMSIIAVVTN-----------------------------------------------CALIALSPQVKAYFPESD-AQLILTVVAIEHVLLA---FKFILAFVIPDVPKHIQVKLSKLDFESLEALKKRKILEVAET--------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O97132-1", "uniprot_id": "O97132_DROME", "id": "O97132-1", "name": "Anoctamin", "aln": "------------------------------------------------------------------------------------------------------------------------------------MSEDAKSPGPRTRNIIENQLFRRQRSLKLEALQRQRTLDSNDGVEGLGADTEPFDKTHIVIIFTEKAKLRHCQDVEKIIQEFGIQTTLEIVGKTEKYLYLSASVDTLLRLADAAELEKMTTTHSMQKFNHG----------CISDFLLPGMGKEQILRYCEIPVLIKDVIQDG----------------------IKSYVQ------------------KGYIEDMFPLHDILYLERFN-WNLKR----TKLPIEDIRNYFGSSIGLYFGFIEFYTKALIFPSLFGILQY--------------------------VFDLN----ISLVCSFYVVWTTIFLELWKRKCAGYSYRWGTIEMS-SLDKPR-------------SAYTGQLKPDPITGKMTLHYPMRYTYLQMY----CISYPVVLGCVVAAGWFALYQFQIEAEVLADFGPD-----SWLLYVPVIVQSVLIAIFSWAYEKLATFLTNLENHRTRSQYDRHRVNKLMLFEIVNNFFSQFYIAFVLHDLRQLKYQLMMQLLVFQLLC----IAQEIGIPLLAV-----------LRQKYAEFRHREVAEEKLRSISDLPRYEQSFYESGLDEYHSTYEDYLQVCIQFGFVVLFAAVAP-FAAIGALLNNVFAVHIDMWKLCNIFKRPFARRAKN----------IGAWQLAFELLSVMSLLSN-----------------------------------------------CGLLFLQPNVKDFFSHWLPSVPDLSFVIFEHLLLG---LKFLIHKVIHERPRWVRIGLLKADFETSQALKQLKKFKAEANKMA-----------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38250-1", "uniprot_id": "IST2_YEAST", "id": "P38250-1", "name": "Increased sodium tolerance protein 2", "aln": "-------------------------------------------------------------------------------------MSQTITSLDPNCVIVFNKTSSANEKSLNVEFKRLNIHSIIEPGHDLQTSYAFIRIHQDNAKPLFSFLQNLDFIESIIPYHDTELSDDLHKLISISKSKILEAPKQYELYNLSNLTNNPKQSLYFAFLQNYIKWLIPFSFFGLSIRFLSNFTYEFNSTYSLFAILWTLSFTAFWLYKYEPFWSDRLSKYSSFSTIEFLQDKQKAQKKASSVIMLKKCCFIPVALLFGAILLSFQLYCFALEIFIKQIYNGPMISILSFLPTILICTFTPVLTVIYNKYFVEPMTKWENHSSVVNAKKSKEAKNFVIIFLSSYVPLLITLFLYLPMGHLLTAEIRTKVFNAFSILARLPTHDSDFIIDTKRYEDQFFYFIVINQLIQFSMENFVPSLVSIAQQKINGPNPNFVKAESEIGKAQLSSSDMKIWSKVKSYQTDPWGATFDLDANFKKLLLQFGYLVMFSTIWPLAPFICLIVNLIVYQVDLRKAVLYSKPEYFPFPIYDKPSSVSNTQKLTVG--LWNSVLVMFSILGCVITATLTYMYQSCNIPGVGAHTSIHTNKAWYLANPINHSWINIVLYAVFIEHVSVAIFFLFSSILKSSHDDVANGIVPKHVVNVQNPPKQEVFEKIPSPEFNSNNEKELVQRKGSANEKLHQELGEKQPASSANGYEAHAATHANNDPSSLSSASSPSLSSSSSSSKTGVVKAVDNDTAGSAGKKPLATESTEKRNSLVKVPTVGSYGVAGATLPETIPTSKNYYLRFDEDGKSIRDAKSSAESSNATNNNTLGTESKLLPDGDAVDALSRKIDQIPKIAVTGGENNENTQAKDDAATKTPLIKDANIKPVVNAAVNDNQSKVSVATEQTKKTEVSTKNGPSRSISTKETKDSARPSNNNTTTTTTTDATQPHHHHHHHRHRDAGVKNVTNNSKTTESSSSSSAAKEKPKHKKGLLHKLKKKL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : :. . : : : . . :. : . : :: :.: . . : .. ::*. :: . : : : : : . . . . : : ::.. : * : :: : . . : : : : .* .. .: : : : * . : . .. : . : :. : : : :. . : . * : . : * * : :: ::. : ** : . * : : . :* :*: : : .: :: .:* : :* : . .* *. . :: : . * :. * ::: :. * . *:*:: : . :* : :* :. :: . : *:: . . : *: :* :: .: : : : . .: : . ", "identical_positions": 26, "similar_positions": 162, "identity": "2.52%" }, { "cls_id": "homologset.agr.RGD:1308261", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "B0BN98-1", "uniprot_id": "B0BN98_RAT", "id": "B0BN98-1", "name": "Protein LLP homolog", "aln": "MAKSLRSKWKR-KMRAEKRKKNAPRELNRLKSILK---VDGDALMKDVEEIATVVVPKH--YQEKMQCDVA----VDDEKDDMKMETEIKRNK--------KTLLDQHGQYPVWMNQR-QRKRLKAKREKKRGKSKAKA---AKGLAW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D945-1", "uniprot_id": "LLPH_MOUSE", "id": "Q9D945-1", "name": "Protein LLP homolog", "aln": "MAKSLRSKWKR-KMRAEKRKKNAPRELNRLKSILR---VDGDALMKDVEEIATVVVAKP--RQEKMQCEEGRCDGADEEKDDMKMETEIKRNR--------KTLLDQHGQYPVWMNQR-QRKRLKAKREKKRGKSRAKA---AKGLAW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BRT6-1", "uniprot_id": "LLPH_HUMAN", "id": "Q9BRT6-1", "name": "Protein LLP homolog", "aln": "MAKSLRSKWKR-KMRAEKRKKNAPKEASRLKSILK---LDGDVLMKDVQEIATVVVPKPKHCQEKMQCEVK------DEKDDMKMETDIKRNK--------KTLLDQHGQYPIWMNQR-QRKRLKAKREKRKGKSKAKAVKVAKGLAW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3B748-1", "uniprot_id": "LLPH_DANRE", "id": "Q3B748-1", "name": "Protein LLP homolog", "aln": "MAKSLRSKWRR-KMRAEKRKKVAPKELARLKSALGQG-EKGEISMKDVAEIATVVPPEK-VKQKPADVDMQ-----EEEADGGKMDLDTKRNK--------KTMLDEHGRYPVWMNQR-QAKKLKAKRVGKNGKPKPKK-----RLAW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VZC8-1", "uniprot_id": "Q9VZC8_DROME", "id": "Q9VZC8-1", "name": "Protein LLP homolog", "aln": "MGRNNRSRKRRDEMNKIKKARYEAKELIRLKKTLGLLDADGNEIMKDISDVVEIKTAKELKREAKSKEEQELIYEHQESLEKGEKVKVTNENTGVEHIFNSKTLKDQYGNYPAWFKKKKTAKRLRKKQHSQKKNFKQAWTTVNVPL--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.:. **: :* :*. *: : .:* ***. * .*: ***: ::. : .: : . : :. : : :.* **: *::*.** *:::: *:*: *: :. : : * ", "identical_positions": 27, "similar_positions": 45, "identity": "18.24%" }, { "cls_id": "homologset.agr.RGD:1308262", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QVP4-1", "uniprot_id": "MLRA_MOUSE", "id": "Q9QVP4-1", "name": "Myosin regulatory light chain 2, atrial isoform", "aln": "MASRKAGTRGK---------------------------------AAATKQAQRGS----------SNVFSMFEQAQIQEFKEAFSCIDQNRDGIICKSDLKETYSQLGRVSVPEEELDAMLQE--------GKGPINFTVFLTLFGEKLN---GTDPEEAILSAFRMFDPSGQGVVNKEEFKQLLMTQADKFSPAEVEQLFALTPMDLAGNIDYKSLCYIIT-HGDEKEE---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1M7K3-1", "uniprot_id": "F1M7K3_RAT", "id": "F1M7K3-1", "name": "", "aln": "MASRKAGTRGK---------------------------------AAATKQAQRGS----------SNVFSMFEQAQIQEFKEAFSCIDQNRDGIICKSDLKETYSQLGRVSVPEEELDAMLQE--------GKGPINFTVFLTLFGEKLN---GTDPEEAILSAFRMFDPSGQGVVNKEEFKQLLMTQADKFSPAEVEQLFALTPMDLTGNIDYKSLCYIIT-HGDEKEE---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q01449-1", "uniprot_id": "MLRA_HUMAN", "id": "Q01449-1", "name": "Myosin regulatory light chain 2, atrial isoform", "aln": "MASRKAGTRGK---------------------------------VAATKQAQRGS----------SNVFSMFEQAQIQEFKEAFSCIDQNRDGIICKADLRETYSQLGKVSVPEEELDAMLQE--------GKGPINFTVFLTLFGEKLN---GTDPEEAILSAFRMFDPSGKGVVNKDEFKQLLLTQADKFSPAEVEQMFALTPMDLAGNIDYKSLCYIIT-HGDEKEE---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P18432-1", "uniprot_id": "MLR_DROME", "id": "P18432-1", "name": "Myosin regulatory light chain 2", "aln": "MADEKKKVKKKKTKEEGGTSETASEAASEAATPAPAATPAPAASATGSKRASGGSRGSRKSKRAGSSVFSVFSQKQIAEFKEAFQLMDADKDGIIGKNDLRAAFDSVGKIAN-DKELDAMLGE--------ASGPINFTQLLTLFANRMATSGANDEDEVVIAAFKTFD--NDGLIDGDKFREMLMNFGDKFTMKEVDDAYDQMVIDDKNQIDTAALIEMLTGKGEEEEEEAA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06580-1", "uniprot_id": "MLC2_YEAST", "id": "Q06580-1", "name": "Myosin light chain 2", "aln": "-----------------------------------------------MDHSES-------------LTFNQLTQDYINKLKDAFQMLDEDEDGLISRGDLTKIYATLGKTLT-DEEWSKMVPDNDTSTAEVGEEGVSFPIFLSIMGKNLS---QFPEREELEESLKAIGRGHDLNVPLNEVIDSLKEAGFENPEEEFAKLFKLFTTNQQATEERTFRGKLFLDSITD------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .::. .*. : * * ::*:**. :* :.**:* : ** : :*: ::* . *: : .. :.*. :*:::.:.: * : ::: :. . : ::. : * . : . *. . : : : :: : ", "identical_positions": 20, "similar_positions": 60, "identity": "8.58%" }, { "cls_id": "homologset.agr.RGD:1308263", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5Y874-1", "uniprot_id": "A0A8I5Y874_RAT", "id": "A0A8I5Y874-1", "name": "AarF domain-containing protein kinase 1", "aln": "------------------------------MARKAIKLASWTSMALAASGVYLYSNSYLDPSDFGAVRVGRAVATTAVISYDYLTSLRSVPYGSE--EYLQRRS-------QVHLRSARRLCELCCANRGTFIKVGQHLGALDYLLPEEYTSTLKVLHSQAPQSSMQEVRQVIREDLGKEIHDLFLSFDDTPLGAASLAQVHKAVLHD----GRTVAVKVQHPKVQAQSSKDILLMEVLVLAVKQLFPDFEFMWLVDEAKKNLPLELDFLNEGRNAEKVAHMLKHFDFLKVPQIHWELS-TKRVLLMEFVEGGQVNDRAYMEKNRIDVNEISCHLGKMYSEMIFVNGF-VHCDPHPGNVLVR-----KRPDTGKAEIVLLDHGLYQVLTEEFRLDYCNLWQSLIWT-DLDRVKYYSQRLG--AADLYPLFACMLTARSWASVKQGIGQAPVSATEDSEIRN--NAACYLPEISQLLNHVPRQMLLILKTNDLLRSIETTLG-TRSSASSFLNMSRCCIR-ALAEHRKRDAGS-FFRRTQISFSEAFSLWQISLHELLLRVKALRLACWVSALLGWLTRAPY--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D0L4-1", "uniprot_id": "ADCK1_MOUSE", "id": "Q9D0L4-1", "name": "AarF domain-containing protein kinase 1", "aln": "------------------------------MARKALKLASWTSVALAASGVYLYSNNYLDPNDFGAVRVGRAVATTAVISYDYLTSLRSVPYGSE--EYLQRRS-------QVHLRSARRLFELCCANRGTFIKVGQHLGALDYLLPEEYTSTLKVLHSQAPQSSMQEVRQVIREDLGKEIHDLFLSFDDTPLGAASLAQVHKAVLHD----GRTVAVKVQHPKVQAQSSKDILLMEVLVLAVKQLFPDFEFMWLVDEAKKNLPLELDFLNEGRNAEKVAHMLRHFDFLKVPQIHWELS-TKRVLLMEFVEGGQVNDRAYMEKNQIDVNEISCHLGKMYSEMIFVNGF-VHCDPHPGNVLVR-----KRPDTGKAEIVLLDHGLYQVLTEEFRLDYCHLWQSLIWT-DMDGLKQYSQRLG--AADLYPLFACMLTARSWDSVKQGIGQAPVSATEDSEIRN--NAACYLPEISQLLNHVPRQMLLILKTNDLLRSIETTLG-TRSSASSFLNMSRCCIR-ALAEHKKRDAGS-FFRRTQISFSEAFSLWQINLHELLLRVRALRLACWVSALLGWLTRAPHRM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86TW2-1", "uniprot_id": "ADCK1_HUMAN", "id": "Q86TW2-1", "name": "AarF domain-containing protein kinase 1", "aln": "------------------------------MARKALKLASWTSMALAASGIYFYSNKYLDPNDFGAVRVGRAVATTAVISYDYLTSLKSVPYGSE--EYLQLRSKSWPVFLQVHLRSARRLCELCCANRGTFIKVGQHLGALDYLLPEEYTSTLKVLHSQAPQSSMQEIRQVIREDLGKEIHDLFQSFDDTPLGTASLAQVHKAVLHD----GRTVAVKVQHPKVRAQSSKDILLMEVLVLAVKQLFPEFEFMWLVDEAKKNLPLELDFLNEGRNAEKVSQMLRHFDFLKVPRIHWDLS-TERVLLMEFVDGGQVNDRDYMERNKIDVNEISRHLGKMYSEMIFVNGF-VHCDPHPGNVLVR-----KHPGTGKAEIVLLDHGLYQMLTEEFRLNYCHLWQSLIWT-DMKRVKEYSQRLG--AGDLYPLFACMLTARSWDSVNRGISQAPVTATEDLEIRN--NAANYLPQISHLLNHVPRQMLLILKTNDLLRGIEAALG-TRASASSFLNMSRCCIR-ALAEHKKKNTCS-FFRRTQISFSEAFNLWQINLHELILRVKGLKLADRVLALICWLFPAPL--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W133-1", "uniprot_id": "ADCK_DROME", "id": "Q9W133-1", "name": "AarF domain-containing kinase 1", "aln": "------------------------------MLLRRVLGYGVVGAGLASAGWSLHTNDY-DPNSLGIVRLSRSAAAVVDVALTYKRELYYKEWDKETPEYKAEKS-------RVHKIAAEKLLQLICINKGVYIKVGQHIGALEYLLPKEFVQTMKVLHSDAPQNPIEDLYKVIRQDLHCNPEEIFDSFEREPLGTASLAQVHKARLKT----GELVAVKVQHPYVKGNSRVDMKTMELAVNVLARIFPDFKIHWLVEESKKNLPIELDFLNEGRNAEKVAKQFKKYSWLRVPKIYWKYS-SSRVLVMEYLEGGHVTDLDYIRRNKIDSFAVANRIGQLYSEMIFRTGF-VHSDPHPGNILVR-----RTPEN-SLEIVLLDHGLYANLTDKFRYDYSNLWLSILKV-DRKAMRQHSEQLGI-KGDLYGLFACMVTGRPWETVMQGLTKVKYSKEEKNTLQN--NTSLVLPHISDVLEQVDRQMLLILKTNDLIRGIESTLR-TQNRMTAFWVMSKCCVQSSYAEQRAKQSDSGSSRILWLRVRERWELFKLNCYYLYLGLINFGFLEALKQVI----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06567-1", "uniprot_id": "MCP2_YEAST", "id": "Q06567-1", "name": "ABC1 family protein MCP2", "aln": "MMTKAFFNKLPFEVFRRYVRTGKSIPQRSPRTRKSLLVGGTIASAVVLYNFNDTFHDSVKHTALTTKRIAVVTQATTRCFYHYKRALNKSYENKK--EREVALN-------KCHKMCALITLHALRSNGGIYIKLGQHIGAMTYLLPKEWTDTMIPLQDHCPESTYEEIDELFKEDLGTSIEDMFLEFNKTPIGVASLAQVHVAKLKNSDGKGSSVAVKCQHPSLKEFIPLDVMLTRTVFELLDVFFPDYPLTWLGDELQSSIYVELNFTKEAENAEKTRHYFSKFKKQTALKIPKVIESHKRILIMEYVGGKRLDDLEYIDSHGISRSEVSSCLSHIFNNMIFTPNVGIHCDPHGGNLAIRSVKPAKDNGYHNFEIVLFDHGLYRYPSTRTRRLYAKFWLSLLFDKDQTKMKKYAKGFANITDEQFPLLAAAITGRSIDAALNYDISTSRTQEEMDVMANGILEGTLLSDLMSILSRIPRVVLLILKTNDLTRHLDECLQNPLGPERTFLIMTQYCAKTVYDEKVERINSEYARWSIKWMWENLTNWIVYERRINQLYFYDFVLWWKKFIPKTWLSS-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . . .:. . :. . . : *:. . :.. * * ..: * . : * .* . * * :**:***:**: ****:*:..*: *:...*:.. ::: :::::** . .::* .*: *:*.******* * *: * **** *** :: *: . . : :**:: : ** :* :..: :**:* :*..****. : : ::. . :* . .*:*:**:: * :: * *: : *. :: :.:::.:*** .. :*.*** **: :* : . ****:***** : . * *.::* *:: * :: ::: :. : : *:*. :*.*. :. . .. : * : * . *..: :*.:: * :********* * :: * . :* *:: * : *: : . : . . * . : : ", "identical_positions": 118, "similar_positions": 169, "identity": "20.24%" }, { "cls_id": "homologset.agr.RGD:1308264", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZCM2-1", "uniprot_id": "D3ZCM2_RAT", "id": "D3ZCM2-1", "name": "T-box transcription factor TBX21", "aln": "MG-IVEPGCGDMLTGTEPIP-SDEGRGTGADQQHRFFYP-ESGAQDP----TDRRAVSSLGSSYSGSALVPAPPGRFLGAYAYPPRAQATGFP---GPGESFPPPAGAEGYPPVDGYAAPDPRAGLYPG------PREDYALPAGLEVSGKLRVALSNHLLWSKFNQHQTEMIITKQGRRMFPFLSFTVAGLEPTSHYRMFVDVVLVDQHHWRYQSGKWVQCGKAEGSMPGNRLYVHPDSPNTGAHWMRQEVSFGKLKLTNNKGASNNVTQMIVLQSLHKYQPRLHIVEVNDGEPEAACSAN-THIFTFQETQFIAVTAYQNAEITQLKIDNNPFAKGFRENFESMYTSVDTSVPSP-PGPNCQLLGG--DPYSPLLSNQYPVS---SRFYP--------DLPGQPKDMVSQSYWLGTPREP--------SYETEFRAVSV-KPTFLPSAPGTTVPYYR------GPDVLAPGAGWPMA----------PQYPPKMSPAGWFRTMRTLPMDPGLGSSEE-----------------QGS-----PSLWTEVTSLQ-PEPSDSGLGEG-DTKRRRISPYPSSGDSSSPAGAPSPFDKE--TEGQFYNYFPN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JKD8-1", "uniprot_id": "TBX21_MOUSE", "id": "Q9JKD8-1", "name": "T-box transcription factor TBX21", "aln": "MG-IVEPGCGDMLTGTEPMP-SDEGRGPGADQQHRFFYP-EPGAQDP----TDRRAGSSLGTPYSGGALVPAAPGRFLGSFAYPPRAQVAGFP---GPGEFFPPPAGAEGYPPVDGYPAPDPRAGLYPG------PREDYALPAGLEVSGKLRVALSNHLLWSKFNQHQTEMIITKQGRRMFPFLSFTVAGLEPTSHYRMFVDVVLVDQHHWRYQSGKWVQCGKAEGSMPGNRLYVHPDSPNTGAHWMRQEVSFGKLKLTNNKGASNNVTQMIVLQSLHKYQPRLHIVEVNDGEPEAACSASNTHVFTFQETQFIAVTAYQNAEITQLKIDNNPFAKGFRENFESMYASVDTSVPSP-PGPNCQLLGG--DPFSPLLSNQYPVP---SRFYP--------DLPGQPKDMISQPYWLGTPREH--------SYEAEFRAVSM-KPTLLPSAPGPTVPYYR------GQDVLAPGAGWPVA----------PQYPPKMSPAGWFRPMRTLPMDPGLGSSEE-----------------QGSS----PSLWPEVTSLQ-PEPSDSGLGEG-DTKRRRISPYPSSGDSSSPAGAPSPFDKE--TEGQFYNYFPN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UL17-1", "uniprot_id": "TBX21_HUMAN", "id": "Q9UL17-1", "name": "T-box transcription factor TBX21", "aln": "MG-IVEPGCGDMLTGTEPMPGSDEGRAPGADPQHRYFYP-EPGAQDA----DERRGGGSLGSPYPGGALVPAPPSRFLGAYAYPPRPQAAGFP---GAGESFPPPADAEGYQPGEGYAAPDPRAGLYPG------PREDYALPAGLEVSGKLRVALNNHLLWSKFNQHQTEMIITKQGRRMFPFLSFTVAGLEPTSHYRMFVDVVLVDQHHWRYQSGKWVQCGKAEGSMPGNRLYVHPDSPNTGAHWMRQEVSFGKLKLTNNKGASNNVTQMIVLQSLHKYQPRLHIVEVNDGEPEAACNASNTHIFTFQETQFIAVTAYQNAEITQLKIDNNPFAKGFRENFESMYTSVDTSIPSP-PGPNCQFLGG--DHYSPLLPNQYPVP---SRFYP--------DLPGQAKDVVPQAYWLGAPRDH--------SYEAEFRAVSM-KPAFLPSAPGPTMSYYR------GQEVLAPGAGWPVA----------PQYPPKMGPASWFRPMRTLPMEPGPGGSEG-----------------RGPEDQGPPLVWTEIAPIR-PESSDSGLGEG-DSKRRRVSPYPSSGDSSSPAGAPSPFDKE--AEGQFYNYFPN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D1YT98-1", "uniprot_id": "D1YT98_DANRE", "id": "D1YT98-1", "name": "", "aln": "MGGIGRNFYLNMLNGTDAQSFAKDAELSSHLHRHRDLSDFKMGIQDTRFYYQDSIPNGQESLTLPFHAEHHQSAGAQTGRFYAPAPLGSCHFTSRSGTGHTYVP-AGADAYSSANGKDVYPSSADGYTASFQHGFPRAPMYSLPGLQVSGKTQVLLNNYPLWAKFHKYQTEMIITKQGRRMFPFLSFNITSLDPSAHYNIYVDVVLADQHHWRYQGGKWVQCGKAEGNMPGNRMYMHPDSPNTGTHWMRQEVSFGKLKLTNNKGSSNNVAQMIVLQSLHKYQPRLHIVEVKEDGTEDPFLTSKTQTFVFPETQFIAVTAYQNADITQLKIDHNPFAKGFRDNYDTLYAPPDPDRLTPSPTESQQLLSGSCYPHQPYLSDQYMSPLPQSRFYSREPVSMTQPCPKDPTSSPHSRWYLSSQQAVPPNRLDFSAYETEYTSNSLYKPFPLQSSPHHPLSYYSENPFTSGAVSSANPGAWTASGRPSPQYLNHPHHSKPTSSLSWFRAVPSPAASSSPTATNSRFHASPSLLEPQRQPLLQDKSKESTEDTWIEAPSVKSVDSADSGLFEGGESKKRRVSPYTSSTENSPPNRSAETCEKDNCSDAGYYGFYTH", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** * . :**.**:. . :.:.. .. :** : : * **. : .. . . . * ... * : *. *. *.*. : * *.*:.* . :* . . *. *.. ** .**:**** :* *.*: **:**:::*******************.::.*:*::**.::*****.********.***********.*****:*:********:*******************:****:********************::. .* . :. *: *.* *************:*******:********:*::::*:. *.. :* * . *:*.* ..* *.:** . ****. * :... . ::*.: : :**:*: : *: ** * *:* .:.** * * ..*. : *::. .. .***.: : . ... .:: :. * * ..:: :.:**** ** ::*:**:***.** :.*.* :... :*: ::. :*.::.:", "identical_positions": 232, "similar_positions": 170, "identity": "38.03%" }, { "cls_id": "homologset.agr.RGD:1308265", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZMA3-1", "uniprot_id": "D3ZMA3_RAT", "id": "D3ZMA3-1", "name": "Diencephalon/mesencephalon homeobox protein 1", "aln": "MQHYGVNGYSLHAMNSLSAMYNLHQQAAQQAQHAPDYRPSVHALTLAERLA-----DIILEARYGSQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRKKQRSLQKEQLQKQKEA--EGSHGEG-KMETPAS-------------NTQLEAEQPPSLPSGDPPAELQLSLSEQSASESAPED-QLDREEDSRA--EEPKAEKSP-GSESKVLGCKRASPKADSPGSLAITPAAPAG--SLLGPSHSYSSSPLSLFRLQEQFRQHMAATNNLVHYSSFEVGGPAPAAAAAAAAAVPYLGVNM---APLSSLHCQSYYQSLSAAAAAHQGVWGTPLLPAPPTGLAPASAALNSKTTSIENLRLRAKQHAASLGLDTLPN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91ZK4-1", "uniprot_id": "DMBX1_MOUSE", "id": "Q91ZK4-1", "name": "Diencephalon/mesencephalon homeobox protein 1", "aln": "MQHYGVNGYSLHAMNSLSAMYNLHQQAAQQAQHAPDYRPSVHALTLAERLAGCTFQDIILEARYGSQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRKKQRSLQKEQLQKQKEA--EGSHGEG-KVEAPAS-------------DTQLETEQPPGLPSGDPPAELQLSLSEQSASESAPED-QLDREEDSRA--EEPKAEKSP-GSESKVPGCKRGSPKADSPGSLAITPAAPGG--GLLGPSHSYSSSPLSLFRLQEQFRQHMAATNNLMHYSSFEVGGPAPAAAAAAAAAVPYLGVNM---APLSSLHCQSYYQSLSAAAAAHQGVWGSPLLPAPPTGLAPASAALNSKTTSIENLRLRAKQHAASLGLDTLPN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NFW5-1", "uniprot_id": "DMBX1_HUMAN", "id": "Q8NFW5-1", "name": "Diencephalon/mesencephalon homeobox protein 1", "aln": "MQHYGVNGYSLHAMNSLSAMYNLHQQAAQQAQHAPDYRPSVHALTLAERLAGCTFQDIILEARYGSQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRKKQRSLQKEQLQKQKEA--EGSHGEG-KAEAPTP-------------DTQLDTEQPPRLPGSDPPAELHLSLSEQSASESAPED-QPDREEDPRAGAEDPKAEKSP-GADSKGLGCKRGSPKADSPGSLTITPVAPGG--GLLGPSHSYSSSPLSLFRLQEQFRQHMAATNNLVHYSSFEVGGPAP-AAAAAAAAVPYLGVNM---APLGSLHCQSYYQSLSAAAAAHQGVWGSPLLPAPPAGLAPASATLNSKTTSIENLRLRAKQHAASLGLDTLPN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8JI10-1", "uniprot_id": "DMX1A_DANRE", "id": "Q8JI10-1", "name": "Diencephalon/mesencephalon homeobox protein 1-A", "aln": "MQHYGVNGYSLHAMNSLSAMYNLHQQAAQQAQHAPDYRPSVHALTLAERLAGCTFQDIILEARYGSQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRKKQRSLQKEQLQKQKDVSTDGALAASDKDEAPSTLNLENQPPSSTSSSSSMEAEAAPHALGSELSVELNVTSAEQSGSESATEDNATDKEEEIKQHREDLKVEKEP-APGNLSPLCKRLSPKPDSPLGSPAISSSSSGVTGGISQSHSYSSSPLSLFRLQEQFRQHMAATNNLVHYPSFDMATPSS---------IPYLGMNVNMPAPLGSLPCQSYYQSLSH---HAQQVWNSPLLQAS-GGLP----SHNSKTTSIENLRLRAKQHAASLGLDTLPN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q566X8-1", "uniprot_id": "DMX1B_DANRE", "id": "Q566X8-1", "name": "Diencephalon/mesencephalon homeobox protein 1-B", "aln": "MQHYGVNGYSLHAMNSLSAMYNLHQQAAQHAQHAPDYRPSVHALTLAERLA-----DIILEARYGSQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRKKQRSLQKEQLQRLKEAGTEGAQDEG-KEEAPP---VEAQAPP-----SPLDGRGLTSAPSCELNEEVNVTSPEQSGAESGAED-TTDREDEPLSIKDEIKEAGPPLMTDDSSPSYKPLSPKSDDPLVSPALPSSS----GAVAQSNSYASSPLSLFRLQEQFRQHMAATNNLMHYPAFDVTAPSS---------LPYLGVNVNMASPLGSLPCQPYYQTLT----QAQQMWSSPLLQGS-GGLP----ALNSKTTSIENLRLRAKQHAASLGLDTLPN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****************************:********************* ***********************************************************************************: *:. :*: . * *:*. : :: . . . : *:::: .***.:**..** *:*:: :: * * . . * ***.*.* . . :. . :. *:**:***********************:**.:*:: *:. :****:*: :**.** **.***:*: * :*.:*** .. **. : ****************************", "identical_positions": 236, "similar_positions": 65, "identity": "58.13%" }, { "cls_id": "homologset.agr.RGD:1308266", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P0C5W1-1", "uniprot_id": "MAP1S_RAT", "id": "P0C5W1-1", "name": "Microtubule-associated protein 1S", "aln": "-----------------------------------------------------------------------------------------MAAVMAAPEPAEAPSS-----------LLLLVVGGECGCPGLLAYVLEELERGVRSWEDVDPDVCSLDEQLKAFVSRHSATFSSIVKGQRSLHHRGETLETLVLLNPSDKSLCDELRNLLMDPAPHKLLVLAGPCLEETGELLLQTGGFSAHHFLQVLGDKEVQDALASAP---AAPALTVSCPTFGDWALLGPAPG-------LRLRLNPPARLPSS-EGLRAFLEYVAESLEPPSPFELLEPPATGGFLRLARPCCYVFPGGLGDAAFFAVNGFTVLVNGGSNPKSSFWKLVRHLDRVDAVLVTHAGADSLPGLNSLLRRKLAEREAAAGPQGQ-HEERLRRLLSPALGVVFLNAREAGSRLR------GGEDEAVCARSLLRSLGIVPLPLQRGPQP-SCPTVLFEKLGVGRLELFVLHPPPG-------------------------------DPAAPACALLVWQPAAPGDKVVRVLFPGRTPPARLLDGLQRLQHLPCLRRPVVTTQDLEV------PSRANSQDSLA--------SRDS----------------------TRKEPVRGTVG-------------------------ATS-RSAVRREP-------ALATR------------------------------------------------------DQKKDTKPG---PTRSTVRDVRRSGPGVVTTKPRVSQ--------------------NGPRAP-------VPAAPPAAPAPEFPGEAENIVES------------------------------------------ERPPAPSPTLSPAQSPPP--TAPGNSPERLSLSP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LRP-EPAPDASPSATTP------------------------------------------------------------------------------------TLTTPSLP----------------AELGSPHSTEVDESLSVSFEQVLP---------------------------------------------------------------------------------AGDAGLSLPLR--LARRSTS---------------PHDVDLCLVSPCEFSHRK------------------------------------------------------------------------------PPPPASPGSS-DSSARSQERP-----PETPPTSVSESLPTLSDSDPVPVAD----------SDDDAGSE-------------SAARDPLPTP-RVPPPLPDAPG----ICMVDPEALPPRARQPLSTANSSRGRKAPARPS------------------------------SASAAPRAA-TVAAKTKGPVGD--RSRPLSARSEPADKPGRVPLTRKPSVPKTVPKMASATRNSSGPSSR--PAPLAAGSPVYLDLAYLPGGGAGHL-DQNFFLRVRALCYVISGQGQRQEEGLRGVLDALLAGKR-------------------------------------------------------------------------QWDLDLQVTLIPTFDSAVMHRWYEETHE-------------------------------QHQALGIRVLGSGSLVSMQDEAFPACKVEF-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C052-1", "uniprot_id": "MAP1S_MOUSE", "id": "Q8C052-1", "name": "Microtubule-associated protein 1S", "aln": "-----------------------------------------------------------------------------------------MAAVMAAPEAVEAPSS-----------LLLLVVGGECGCPGLLAYVMEELERGVRSWEDVDPAVCSLDEQLKAFVSRHSATFSSIVKGQRSLHHRGETLETLVLLNPSDKSLCDELRNLLMDPAPHKLLVLAGPCLEETGELLLQTGGFSAHHFLQVLGDKEVQDALASAP---AAPALTVSCPTFGDWALLGPVPG-------LQLRLNPPAQLPAS-EGLRAFLEYVAESLEPPSPFELLEPPAAGGFLRLARPCCYVFPGGLGDAAFFAVNGFTVLVNGGSNPKSSFWKLVRHLDRVDAVLVTHAGADSLPGLNSLLRRKLAEREAAAGPQGQ-HEERLRRLLSPALGVVFLNAREAASRLR------GGEDEAVCARSLLRSLGIAPLPLQRGPQP-SCPTVLFEKLGVGRLELFVLHPPPG-------------------------------DPAAPACALLVWQPAAPGDKVVRVLFPGRTPPARLLDGLQRLQHLPCLRRPVVTTHDLEA------PSRANSQDSLA--------SRDS----------------------ARKEPVRGTVG-------------------------SIANRSTVRREP-------ALATR------------------------------------------------------DQKKDTRSG---PTQPTARDTRRSGPGVVNTKPRVSQ--------------------NGPRAP-------VLAAPLTAPVAECPGEAENILES------------------------------------------ERPPAPSPTLSPAQSPPP--TAPGNSPERLSLSP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LRP-EPAPDASPSATTP------------------------------------------------------------------------------------TLTTPSLP----------------AELGSPHSTEVDESLSVSFEQVLP---------------------------------------------------------------------------------AGDPGLSLPLR--LARRSTS---------------PHDVDLCLVSPCEFSHRK------------------------------------------------------------------------------PPPPASPGSS-DSSARSQERP-----PETPPTSVSESLPTLSDSDPVPVAD----------SDDDAGSE-------------SAARDPPPTP-RVPPPLPDVPG----ICMVDPEALPPRARQPLNTTNPSRSRKAPARPS------------------------------SASATPRAA-TVAAKTKGPAGD--RNRPLSARSEPADRPGRVPLTRKPSVPKTVPKMASATRLSSGPSGR--PAPLAAGSPVYLDLAYLPGGGAGHL-DQNFFLRVRALCYVISGQGQRQEEGLRAVLDALLAGKR-------------------------------------------------------------------------QWDLDLQVTLIPTFDSAVMHRWYEETHA-------------------------------QHQALGIRVLGSGSLVSMQDEAFPACKVEF-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q66K74-1", "uniprot_id": "MAP1S_HUMAN", "id": "Q66K74-1", "name": "Microtubule-associated protein 1S", "aln": "-----------------------------------------------------------------------------------------MAAVAGS--GAAAAPS-----------SLLLVVGSEFGSPGLLTYVLEELERGIRSWD-VDPGVCNLDEQLKVFVSRHSATFSSIVKGQRSLHHRGDNLETLVLLNPSDKSLYDELRNLLLDPASHKLLVLAGPCLEETGELLLQTGGFSPHHFLQVLKDREIRDILATTPPPVQPPILTITCPTFGDWAQLAPAVPGLQGALRLQLRLNPPAQLPNS-EGLCEFLEYVAESLEPPSPFELLEPPTSGGFLRLGRPCCYIFPGGLGDAAFFAVNGFTVLVNGGSNPKSSFWKLVRHLDRVDAVLVTHPGADSLPGLNSLLRRKLAERSEVAAGGGS-WDDRLRRLISPNLGVVFFNACEAASRLA------RGEDEAELALSLLAQLGITPLPLSRGPVP-AKPTVLFEKMGVGRLDMYVLHPPSAG----------------------------AERTLASVCALLVWHPAGPGEKVVRVLFPGCTPPACLLDGLVRLQHLRFLREPVVTPQDLEG------PGRAESKESVG--------SRDS----------------------SKREGLLATHPRPGQE------------------RPGVARKEPARAEAPRKTEKEAKTPR------------------------------------------------------ELKKDPKPS---VSRTQPREVRRAASSVPNLKKTNAQAAPKPRKAPSTSHSGFPPVANGPRSPP-----SLRCGEASPPSAACGSPASQLVATPSLE--------------------------LGPIPAGEEKALELPLAASSIPRPRTPSPESHRSPAEGSERLSLSP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LRGGEAGPDASPTVTTP------------------------------------------------------------------------------------TVTTPSLP----------------AEVGSPHSTEVDESLSVSFEQVLPPSAP-----------------------------------------------------------------------------TSEAGLSLPLRGPRARRSAS---------------PHDVDLCLVSPCEFEHRKAV--------------------------------------------------------------------------PMAPAPASPGSSNDSSARSQERAGGLGAEETPPTSVSESLPTLSDSDPVPLAPGA--------ADSDEDTEGF----------GVPRHDPLPDPLKVPPPLPDPSS----ICMVDPEMLPPKTAR--QTENVSRTRKPLARPN------------------------------SRAAAPKATPVAAAKTKGLAGGDRASRPLSARSEPSEKGGRAPLSRKSSTPKTATRGPSGS-ASSRPGVS--ATPPKS--PVYLDLAYLPSGSSAHLVDEEFFQRVRALCYVISGQDQRKEEGMRAVLDALLASKQ-------------------------------------------------------------------------HWDRDLQVTLIPTFDSVAMHTWYAETHA-------------------------------RHQALGITVLGSNSMVSMQDDAFPACKVEF-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PDQ3-1", "uniprot_id": "A0A8M9PDQ3_DANRE", "id": "A0A8M9PDQ3-1", "name": "", "aln": "-----------------------------------------------------------------------------------------MAAEHIGELASMENSNRGARPGFCSEKYSLLVIVGQPGPAGFVDLLVSEIERGLRSWD-VDSSACNIDEQLKLFISRHSAFFSEDLKGQKTLQHSGDVLETQVIVNPSHDLVCSEVRRLISDTSLHKLLILAGQCVEETGDLVLQTGSFSLEDFIQIFTDEEIGDLLSSADP-TQKARLTLSCPESGKWKTSQLEKHN--LQDYIEIKTNPPLVLPEM-EGLQEFTEYLSESLEPQSPFDLLVPPSTVGFLKLSRPCCYVFPGGRGDSAFFAVNGFNVLVNGGSDARSCFWKLVRHLDRVDSVLLTHAGVDNLPGINSLLYRKVAEHEEEQSAGSQSSEDWQKNLISPEIGVVFFNASERLKKLQSDPRVIRSSDQVSLTLQHLEKLSIFPERLSRSAGPTIEPVILFQKMGVGRLDLYVLNPVKGSKELEAFLQTWPA------SPPNIKPTDIPLESIVSICALLVWHPANPREKIIRVLFPGCTPQSKIFEGLERLKHLEFLKHSVVSLKDLEASKLDKQPKHTGSKESLKSI------SKESRPGSALLKDKVVKVDPKKQDTKTKTKPTNETVPKEGKESEEKAKPKDDVKLRPKTAEKQVAKKEPAKDEKKEVRKKEEKPPTSIAKKDENVEKRKEPLKKD-------------------LGAKPKKDIIKPDLKKEIKKEVKPEDKRTTKPPVKEVKKPAGSLPGNTESRKSVGKNGSLKKDVLVSKKDPVTKGKPKPDKKEPDNVKSSSGDNSKTSTPEDISKQLEKLKLDNEHGSLQDAEGNNMSSRTASDSSAGQVNGSKTGTEESPEKFRSMDGTPGSNNPSPLTKTPKSERSVNFDLTPTE----------------------------------------------------------------------------------------------------------------------------------------------------------------LDGCLKEDACTSSDEKTLELVSPADSGKNSSWQTRYPQSPDNACLDSSEDCKVGIRKSGLAVEDGQLGICKNSRSNIENSSISSQDRQSSFLSS---------------------TSFKDGSTSITSFP----------------AEVGSPHSTEVEDSLSVSFEQVPVCHPQEEMGSLAYTNGHLA-------------------------------------------------------------DRDPKADMSLPLKTSHNSHHAYDDSENHLYGLQGDVLPHDVDLCLVSPCEFKHHKSL--------------------------------------------------------------------------E-NQQGLSSEVAAPSPDLSQEPLRDHQSQETT-SSVSVSLISVSDSDVPPATEECPSISEELDSEEDTTSDLFPPHHPSSHSLHHNSQDPPPAPMKDLPPLPPQRG----ACMADPEAD--------SQGKSSKNVTAKTKKT------------------------------AAAAPTKTG---SANVVAQTGKTKIGGPVSATG-----TIRVTSSLDTRPPSRSAIGGSRPTSSKSSSSS--ASVSLGSAPVCLDLAYLPSGSAAHTVDVEFFRRLRSSCYIISGDEPHKETVMRSILDSLLEGKA-------------------------------------------------------------------------SWP-DVQVTLIPTFDSLSMHNWYQQTHE-------------------------------RQKDLSITVLGSNSTVAMQDETFPACKVEF-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W596-1", "uniprot_id": "FUTSC_DROME", "id": "Q9W596-1", "name": "Microtubule-associated protein futsch", "aln": "MGDQPKATTTATGGAAGPVPEGDAVMATTNQDALAKGAGDGPAQDAAQEPGQAEHGEPGDGGDGGDDGATDAGASSLPPSEIGGRAPLDTACSDADGGAPSSLAGGIVGPPSPLTGCYLLIVLGEPHSEEHKDNILQHLLKGFLSWD-VSDCHVDLEEELN-TITQHAPEGEEARHGERLIQYASENLVTEVLIHPQYNTLIQCMRNLLSSFTRHRHIIHAGYTFSGNGSWILQDGTFSVADFSEAFQEHDVQRVIRAYAD---TITMNIHCADAGLWHTLPEKAFAR----QCRIRINPVDVLDTSSECINGFIDYLAPMVMPTSLRELLETSDVVGNIRFTHPTLYVFPGGQGDAALFGINGFNMLVDGGFNRKACFWDFARHLDRLDAVLMTRLNNSNVQGLGAVVSRKRDAHVYPQIGHFFGNVPDRKGLPSPDGDKDRDPLLIDLFERG------------HGIVSDLKALDLKPQCCYRNQEP----VNLYHKVGHGTLDMYVISPARDSKEVKEFLQKWHAGDQRLFAARDSRDFNFPLQNLVSICALLVWQPANPDDTITRILFPGSTPDFKIQEGLEKLKHLEFMKHSTCTAKSIAPAIQTVTSTRKSLKSAIEATPAPPSASYKTTKFSPVASAALAVQHPQQQDNKAKEAAAAAAAAAAAAASAATIARAKADSMDTDAEPEHEADPEPADTGDEAAPTEQEPEAETEPEPEHEPEAEQDKDVGEEKKVEVLIMKPQQATPAVIAASGKDGVDAASADATPTGKLSKASAKGKADKPRAEVKPVVRSRIDTKPPKSMDRKLAKRDEKKSSPTTTPAARAPVAQNAKPKVLSRPATKSSPSSTPAKSAKEANNRKVLESKQQAARVQATSTVSRR-------VTSTASERRVQQQAEAKTAATGATQATQRKPISRRPRGVSPSKRAPAPGSPVKQAKPKAADLKKTRLDKGGTTDSSLVSTPSADEATAAKKLQDLTASQELDAEKQRELDDLKEEQEVVREIEAVFSRDEMKRQQHQQIKAELREMPAEGTGDGENEPDEEEEYLIIEKEEVEQYTEDSIVEQESSMTKEEEIQKHQRDSQESEKKRKKSAEEEIEAAIAKVEAAERKARLEGASARQDESELDVEPEQSKIKAEVQDIIATAKDIAKSRTEEQLAKPAEEELSSPTPEEKLSKKTSDTKDDQIGAPVDVLPVNLQESLPEEKFSATIESGATTAPTLPEDERIPLDQIKEDLVIEEKYVKEETKEAEAIVVATVQTLPEAAPLAIDTILASATKDAPKDANAEALGELPDSGERVLPMKMTFEAQQNLLRDVIKTPDEVADLPVHEEADLGLYEKDSQDAGAKSISHKEESAKEEKETDDEKENKVGEIELGDEPNKVDISHVLLKESVQEVAEKVVVIETTVEKKQEEIVEATTVITQENQEDLMEQVKDKEEHEQKIESGIITEKEAKKSASTPEEKETSDITSDDELPAQLADPTTVPPKSAKDREDTGSIESPPTIEEAIEVEVQAKQEAQKPVPAPEEAIKTEKSPLASKETSRPESATGSVKEDTEQTKSKKSPVPSRPESEAKDKKSPFASGEASRPESVAESVKDEAGKAESRRESIAKTHKDESSLDKAKEQESRRESLAESIKPESGIDEKSALASKEASRPESVTDKSKEPSRRESIAESLKAESTKDEKSAPPSKEASRPGSVVESVKDETEKSKEPSRRESIAESAKPPIEFREVSRPESVIDGIKDESAKPESRRDSPLASKEASRPESVLESVKDEPIKSTEKSRRESVAESFKADSTKDEKSPLTSKDISRPESAVENVMDAVGSAERSQPESVTASRDVSRPESVAESEKDDTDKPESVVESVIPASDVVEIEKGAADKEKGVFVSLEIGKPDSPSEVISRPGPVVESVKPESRRESSTEIVLPCHAEDSKEPSRPESKVECLKDESEVLKGSTRRESVAESDKSSQPFKETSRPESAVGSMKDESMSKEPSRRESVKDGAAQSRETSRPASVAESAKDGADDLKELSRPESTTQSKEAGSIKDEKSPLASEEASRPASVAESVKDEAEKSKEESRRESVAEKSPLPSKEASRPASVAESIKDEAEKSKEESRRESVAEKSPLPSKEASRPASVAESIKDEAEKSKEESRRESVAEKSPLPSKEASRPASVAESIKDEAEKSKEESRRESVAEKSPLPSKEASRPASVAESIKDEAEKSKEESRRESVAEKSPLPSKEASRPASVAESIKDEAEKSKEESRRESVAEKSPLPSKEASRPASVAESIKDEAEKSKEESRRESVAEKSPLPSKEASRPASVAESIKDEAEKSKEETRRESVAEKSPLPSKEASRPASVAESIKDEAEKSKEESRRESAAEKSPLPSKEASRPASVAESVKDEADKSKEESRRESMAESGKAQSIKGDQSPLKEVSRPESVAESVKDDPVKSKEPSRRESVAGSVTADSARDDQSPLESKGASRPESVVDSVKDEAEKQESRRESKTESVIPPKAKDDKSPKEVLQPVSMTETIREDADQPMKPSQAESRRESIAESIKASSPRDEKSPLASKEASRPGSVAESIKYDLDKPQIIKDDKSTEHSRRESLEDKSAVTSEKSVSRPLSVASDHEAAVAIEDDAKSSISPKDKSRPGFVAETVSSPIEEATMEFSKIEVVEKSSLALSLQGGSGGKLQTDSSPVDVAEGDFSHAVASVSTVTPTLTKPAELAQIGAAKTVSSPLDEALRTPSAPEHISRADSPAECASEEIASQDKSPQVLKESSRPAWVAESKDDAAQLKSSVEDLRSPVASTEISRPASAGETASSPIEEAPKDFAEFEQAEKAVLPLTIELKGNLPTLSSPVDVAHGDFPQTSTPTSSPTVASVQPAELSKVDIEKTASSPIDEAPKSLIGCPAEERPESPAESAKDAAESVEKSKDASRPPSVVESTKADSTKGDISPSPESVLEGPKDDVEKSKESSRPPSVSASITGDSTKDVSRPASVVESVKDEHDKAESRRESIAKVESVIDEAGKSDSKSSSQDSQKDEKSTLASKEASRRESVVESSKDDAEKSESRPESVIASGEPVPRESKSPLDSKDTSRPGSMVESVTAEDEKSEQQSRRESVAESVKADTKKDGKSQEASRPSSVDELLKDDDEKQESRRQSITGSHKAMSTMGDESPMDKADKSKEPSRPESVAESIKHENTKDEESPLGSRRDSVAESIKSDITKGEKSPLPSKEVSRPESVVGSIKDEKAESRRESVAESVKPESSKDATSAPPSKEHSRPESVLGSLKDEGDKTTSRRVSVADSIKDEKSLLVSQEASRPESEAESLKDAAAPSQETSRPESVTESVKDGKSPVASKEASRPASVAENAKDSADESKEQRPESLPQSKAGSIKDEKSPLASKDEAEKSKEESRRESVAEQFPLVSKEVSRPASVAESVKDEAEKSKEESPLMSKEASRPASVAGSVKDEAEKSKEESRRESVAEKSPLPSKEASRPASVAESVKDEADKSKEESRRESGAEKSPLASKEASRPASVAESIKDEAEKSKEESRRESVAEKSPLPSKEASRPTSVAESVKDEAEKSKEESRRDSVAEKSPLASKEASRPASVAESVQDEAEKSKEESRRESVAEKSPLASKEASRPASVAESIKDEAEKSKEESRRESVAEKSPLASKEASRPTSVAESVKDEAEKSKEESSRDSVAEKSPLASKEASRPASVAESVQDEAEKSKEESRRESVAEKSPLASKEASRPASVAESVKDDAEKSKEESRRESVAEKSPLASKEASRPASVAESVKDEAEKSKEESRRESVAEKSPLPSKEASRPTSVAESVKDEAEKSKEESRRESVAEKSSLASKKASRPASVAESVKDEAEKSKEESRRESVAEKSPLASKEASRPASVAESVKDEAEKSKEESRRESVAEKSPLPSKEASRPTSVAESVKDEADKSKEESRRESGAEKSPLASMEASRPTSVAESVKDETEKSKEESRRESVTEKSPLPSKEASRPTSVAESVKDEAEKSKEESRRESVAEKSPLASKESSRPASVAESIKDEAEGTKQESRRESMPESGKAESIKGDQSSLASKETSRPDSVVESVKDETEKPEGSAIDKSQVASRPESVAVSAKDEKSPLHSRPESVADKSPDASKEASRSLSVAETASSPIEEGPRSIADLSLPLNLTGEAKGKLPTLSSPIDVAEGDFLEVKAESSPRPAVLSKPAEFSQPDTGHTASTPVDEASPVLEEIEVVEQHTTSGVGATGATAETDLLDLTETKSETVTKQSETTLFETLTSKVESKVEVLESSVKQVEEKVQTSVKQAETTVTDSLEQLTKKSSEQLTEIKSVLDTNFEEVAKIVADVAKVLKSDKDITDIIPDFDERQLEEKLKSTADTEEESDKSTRDEKSLEISVKVEIESEKSSPDQKSGPISIEEKDKIEQSEKAQLRQGILTSSRPESVASQPESVPSPSQSAASHEHKEVELSESHKAEKSSRPESVASQVSEKDMKTSRPASSTSQFSTKEGDEETTESLLHSLTTTETVETKQMEEKSSFESVSTSVTKSTVLSSQSTVQLREESTSESLSSSLKVEDSSRRESLSSLLAEKGGIATNTSLKEDTSASASQLEELLVQSEECSSESIVSEIQTSIAQKSNKEIKDARETKVTSQFTTTTSSATKDDSLKETVAEFLATEKIVSAKEAFSTEATKSADDCLKKTTASAVSSTSASQRALFVGTDESRRESLLSQASESRLTHSDPEDEEPADDVDERSSVKESRSKSIATIMMTSIYKPSEDMEPISKLVEEEHEHVEELAQEVTSTSKTTTLLQSSEQSSTTTSSTSKTGASRVESITLTQMDQQTSQSQGDPADRKTPPTAPVSPGVKAMSSTGSAGSVIGAGAGAVAAGGKCESSAASIVSSSGPMSPKDISGKSSPGALTSESQSIPTPLGRESHTDTPESSPKPTSPFPRVSKDELKSLEMQHHSQEQMLAGAAAAAGAECEGDIPELHELRGLECTTALSGSTDKIITTTITTVTKVISADGKEIVTEQKTVTTTDSSEPDSEKVVVTTTRTTSESERDQLLPKEVALLRGLYRASTPGSEDDEDLLLGSPRSATSYELQHSSSGVSKRSDLDADGDESQDDIPPQYGSEEHSTARSILLPRTADPMATSFYGALPDSFDVVMKPSTEPIPIQGAPSGDSQSSESVESSSQTWAGHKFLDQADKDFQRALEEHVQARGAEVMSSVTAKYSYSPSKAEEMEQIVSGTAERQRFPLSDVQRARVAESGFATVGSVASQQQQQEKGGEVEQAVPTTTAVTASTTATASSTGALPKDRLEEWGKPLGLPSPAPLPVEGGADIRTTPKKERRLVATKTRLNNEKNLRRRSESPNKAGKKPAPVYVDLTYVPHNGNSYYAHVDFFKRVRARYYVFSGTEPSRQVYDALLEAKQTWEDKELEVTIIPTYDTDVLGYWVAENEELLAKHRIDLSPSASRCTINLQDHETSCSAYRLEF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. .. **:: .: ::..: :*. **: *. .::*:*: :::*:. .. :*:: ::: .: * * *:::*. . : . :*.*: . : *: :: ** .. .*. :** * ** .* : : :.:: : : :.: *. * * .:: ** * * : * :*:: : * * :** .. * ::: :* *:**** **:*:*.:***.:**:** : ::.**.:.*****:*:**:*: . ..: *:.::: ** : : * ** . . . * *.: * *. * . *:.*:* * *:::*: * .. ******:** * :.: *:**** ** : :** :*:** ::... : :.: . : :.:: * .: :: : : ... . * :. : :.: . . .. . . . .: * : . * . . . . :* : .. : * * : : .::* * ..*: ::: *: *. .:* . : : *:.**:. * * :. .. .. .:* * ::. .: : .::: : .. : . * * : . . ** : : . :: : *. .: :.. . . . * . .. : .. * . .. . . *: : . * . * . . * . : * : : * :..: * : .. .: ::**: * :. :.. :: . :: . :: : * .*** ", "identical_positions": 149, "similar_positions": 301, "identity": "2.7%" }, { "cls_id": "homologset.agr.RGD:1308267", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZV81-1", "uniprot_id": "D3ZV81_RAT", "id": "D3ZV81-1", "name": "HEAT repeat-containing protein 3", "aln": "MGKSRTKRFKRPQFSPVGSCQAEAAATANGTGDEEDDGLAAELLEKLQHPSAEVRECACAGLARLVQQRPALPDLARRDAVRRLG-PLLLDSSLAVRETAAGALRNLSACGGFDVCDDMVAKDIMTPLVALLRECSSGLDSNEMSPQEKADKKRNSIESIANEAVNVLWNVCECSSRAVSIFNKEGCLEIVLQYLRRFPTSIDLAVSVAYCLQTVTEDNPELLKSFDGTALRVLESALLCPVTSMEYILLKTLVAGTIWNLKDIIPSKSQAEIINAILNTLSEVLGVNAGDTVIQMKEAETQRLKDAAESEDILANANGDGEMEFQDDEMEEIPHKRKLRRKTFISDLLPSTDKELREAMALLTAQQTALEVIVNMCCSEDPSDDEWEELSSSDESEAFMENSFNECSGQLMSPLCLSHEIHSALTNCLIPKKVFEKTSSPNSDAVDICSKNPTWKPLIRKMSTIQCRALMCLQSLVSLLDIDHLGGAPALQTLAQHLSQLLFSQPDFAKHADFLEAISSALRALLQTMAS-KNIPQCMTPEQLMTLCREGIHSSSIGVRVNVVSILGITGSVLAKEDGTLETLKTIGCFLLEVTTKDPSLVVAGEALDALFDVFADGEEAEKASVQIKLLAALKEFQPVFKMKMRKEGRARYSPDQLCVLDNVKMNLRRFIAYQETVEKRLTS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BQM4-1", "uniprot_id": "HEAT3_MOUSE", "id": "Q8BQM4-1", "name": "HEAT repeat-containing protein 3", "aln": "MGKSRTKRFKRPQFSPIESCQAEAAAASNGTGDEEDDGPAAELLEKLQHPSAEVRECACAGLARLVQQRPALPDLARRDAVRRLG-PLLLDSSLAVRETAAGALRNLSACGGFDVCDDMVAKDIMTPLVALLRECLSGLDSNEMSPQEKADK-RNPVESIANEAVNVLWNVCECSGRAVSIFNKEGCLEIVLQYLRRFPTSIDLAVSVAYCLQTVTEDNPELLKSFDGTALRVLESALLCPVASMEYILLKTLVAGTIWNLKDIIPSKSQAEIINAILGALSEVLGMNTGNMVIQMKEAETQRLKTAAESEDILANANGDDLVE--DDEMEEIPHKRKLRRKTFISDLLPPTDKELREAMALLTAQQTALEVIVNMCCSEDPSDDEWEELSSSDESEAFMENSFSECSGHLMSPLCLSHEIHSALTNCLIPEKVFEKTSSPNSVAVDICSKNPTWKPLIRKMNTIQCRALMCLQSLVSLLDIDHLGGAPALQTLAQHLSQILFSQPDFAKHDDFLEAISSALRALLQTMAS-KNIPQCMTPEQLMTLCREGIHSSSIGVRVNVVSILGITGSVLAKDDGTLDTLKTIGCFLLEVATKDPSLVVTGEALDALFDVFADGEAAEKASVQIKLLAALKEFQPVFKMKIRKEGRGKYSPDQLCVLDNVKMNLRRFIAYQETVEKRLTS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z4Q2-1", "uniprot_id": "HEAT3_HUMAN", "id": "Q7Z4Q2-1", "name": "HEAT repeat-containing protein 3", "aln": "MGKSRTKRFKRPQFSPTGDCQAEAAAAANGTGGEEDDGPAAELLEKLQHPSAEVRECACAGLARLVQQRPALPGLARRDAVRRLG-PLLLDPSLAVRETAAGALRNLSACGGFEVCDDMVTKDIMTPLVALLKECSAGLDSNEMSLQEKKDQNRNSIENIANETVNVLWNICECSSRAVSIFNKEGCLEIVLKYLSRFPTNVDLAISVAYCLQTVTEDNPELLKSFSATALNMLESALLSPVSSMESLLLKTLVAGTIWNLKDIIPCKSQAEIINALLKILSEVLGMDAGEMVIQMKEAETQRLKTAAEAEEILENTNGDDLIE--DDEMEGISHKRRVRRKTFVSDLLPPTDKELRETIALLTAQQTALEIIVNMCCNEDPSDDEWEELSSSDESDAFMENSFSECGGQLFSPLCLSHEVHTALTNYLIPKKIFEKTAFPNSIAVDLCSRNPTWKPLIRKMNTIQCRALFCLQSLVSLLDVEHLGGAAALQTLAQHLSQLLFSQPDFAKHVDFLEAISSALRALLQTMAS-KNISQCMTPDQLMTLCKAGIHSSNVGVRVNVVSILGITGSVLAKEDGTLETLKNIGCFLLEVTTKDPSLVVAGEALDALFDVFADGKEAERASIQIKLLSALKEFQPVFKMKIRKEGRGNYSTDQLCVLDNVKMNLRRFIAYQETVEKRLTS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VI15-1", "uniprot_id": "Q9VI15_DROME", "id": "Q9VI15-1", "name": "SYO1-like TPR repeats domain-containing protein", "aln": "MGKVRKVKTRTP-----SGVDTSAEIDVESAGEAEGCGPIEAICVHLQQANVEEKLNGLHSFAVLALRKEKVPEIRDSELVRIAA-PLLCDKESAIRNAAAGAFRNLSVFG-TEVCDFLVENDILTALLTLVRSYDLTKGGFENELH----------ADTFQQAIHLLRNLCESSPTATEALNQANFLSSLLLGFDYRKFGLEVAISVAQLVLVVSENNSSSWNVLASS--TILPELLVAPTESHAQLYLNALAAGILCNVPACAAAHT-----REILNSLDKLLSIDP-QAQLQSCKSEILNAKSKNEAPVLEISMETEDMTETQSANQSKPNQ--------------CDAEVALKNLEHLLDAQRLVAEIITNLGSSDEQSN--WDTDSEHSESESVADYDMEDETADSGS-GGLPANFLETIKQNKVIEKLWQKAQPLQPAVENLVSQQ---ENIKEKVEKLRVSYLICLQNLCNVLPPEDLGGCSNLYNMWMILGQQAFRG---SEDVSVMEAITSLMRSSLSLLKSRKDLFGQMTENDLNMIIEGASKCTDINIRVNWNRMLGTLGSLLSEP-----LVKAIVLFLLTYCAQEDDLWALSEGLDALMDIFAVDD-WPQIIAELEMCDRVQALEELFKSKLRQQRRE--LKERRATVQTVKTNFSRFVFYLNKNCKK---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q07395-1", "uniprot_id": "SYO1_YEAST", "id": "Q07395-1", "name": "Synchronized import protein 1", "aln": "MGRSKKRSRASS---SRLNPLRKAGSNDNNKDTNVVNKKLQPLLQNLSSVVPNDRSIALSSISVLCEDAHMRQLLLKEKLVPIILNKLLNDSNSDIVVESFGLLRNLSLEEGYDVSIYLWRSDIWTSITSNFGRIVESLSALQAAEQQPQ---LKPAGKSKIESKRLLFDFADNLLSLVVALSNG--SDDILNEILTESKINEIFQVISQLLKYGVEKLP---INLFNTTLDLIYDLSSESFEFIDHVSNNELLSQFLNGLSPALHPQAN-----ELTKVLIEGIHCQFLDMKITYDQCNKMIHSVCHSINNIDPVQLVNDINN----------------------------PVEIGPATSKDESSKVITKIKDYNAKRNESMIKLQSIEIAIDLITAIIEIVASKYESPESQEVAIPEELINTLTN--FLPHVFMILKDTFTSRILIGWNNLIWLFVSLSLTELSGELLTTLWSYVTQLDSQDD-LSIKIGRMGCIWALLKLIFPDGAFESENRALINVQMLNNSGFARG---------------IIEEFQNNNDLELQQKCINVLSTYAMIQGQIDANKEIGQFFIQTLTQLNVRPEILIEMTNSLFQIYGDASYDYNEPIFVRGGFLSILKDQVVPNLRQQFKMVDKNK-NPELKERCHDCFTTLDSFIHYKMNENSTNQ-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: :. . . .* :. . : :*. : : . .:: * : . * ** * . : : * :**** :*. : .** *.: : . .. : : . :: .:* :..: . :.: . :* : :: :: : *. . : : :: . . : : * : : .: :: : * : : : : : :.: . . : :. : : :.: :: :: . . :. : .. . . :. :. ::.: . ::: . : .: : .: : * * . . * :. . : : . : : . . *. : . : . : ..: :: : :*. . : .: : : * .: * :.* : . : . : . . :: ::: : : . .: *: * . . ", "identical_positions": 33, "similar_positions": 181, "identity": "4.82%" }, { "cls_id": "homologset.agr.RGD:1308269", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JHK5-1", "uniprot_id": "PLEK_MOUSE", "id": "Q9JHK5-1", "name": "Pleckstrin", "aln": "MEPKRIREGYLVKKGSVFNTWKPMWVVLLEDGIEFYKKKSDNSPKGMIPLKGSTLTSPCQDFGKRMFVLKITTTKQQDHFFQAAFLEERDAWVRDIKKAIKCIEGGQKFARKSTRRSIRLPETIDLGALYLSMKDPEKGIKELNLEKDKKVFNHCLTGSGVIDWLVSNKLVRNRQEGLMISASLLSEGYLQPAGDLSKNAADGIAENPFLDSPDAFYYFPDSGFFCEENSSDDDVILREEFRGVIIKQGCLLKQGHRRKNWKVRKFILREDPAYLHYYDPAGGEDPLGAVHLRGCVVTSVESSHDVKKSDEENLFEIITADEVHYYLQAATSKERTEWIKAIQVASRTGK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4KM33-1", "uniprot_id": "PLEK_RAT", "id": "Q4KM33-1", "name": "Pleckstrin", "aln": "MEPKRIREGYLVKKGSVFNTWKPMWVVLLEDGIEFYKKKSDNNPKGMIPLKGSTLTSPCQDFGKRMFVLKITTTKQQDHFFQAAYLEERDAWVRDIKKAIKCIEGGQKFARKSTRRSIRLPETIDLGALYLSMKDPEKGIKELNLEKDKKVFNHCFTGSGVIDWLVSNKLVRNRQEGLMISASLLSEGYLQPASDLSKNAADGIAENPFLDNPDAFYYFPDSGFFCEENSSDDDIILKEEFRGIIIKQGCLLKQGHRRKNWKVRKFILREDPAYLHYYDPAGGEDPLGAIHLRGCVVTSVESNPDGKKSDEENLFEIITADEVHYYMQAATAKERTEWIKAIQVASRTGK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P08567-1", "uniprot_id": "PLEK_HUMAN", "id": "P08567-1", "name": "Pleckstrin", "aln": "MEPKRIREGYLVKKGSVFNTWKPMWVVLLEDGIEFYKKKSDNSPKGMIPLKGSTLTSPCQDFGKRMFVFKITTTKQQDHFFQAAFLEERDAWVRDIKKAIKCIEGGQKFARKSTRRSIRLPETIDLGALYLSMKDTEKGIKELNLEKDKKIFNHCFTGNCVIDWLVSNQSVRNRQEGLMIASSLLNEGYLQPAGDMSKSAVDGTAENPFLDNPDAFYYFPDSGFFCEENSSDDDVILKEEFRGVIIKQGCLLKQGHRRKNWKVRKFILREDPAYLHYYDPAGAEDPLGAIHLRGCVVTSVESNSNGRKSEEENLFEIITADEVHYFLQAATPKERTEWIRAIQMASRTGK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******************************************.*************************:***************:**************************************************.**************:****:**. ********: **********::***.*******.*:**.*.** *******.**********************:**:*****:**************************************.******:************. : :**:***************::****.*******:***:******", "identical_positions": 315, "similar_positions": 30, "identity": "90.0%" }, { "cls_id": "homologset.agr.RGD:1308270", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "B7Z080-1", "uniprot_id": "B7Z080_DROME", "id": "B7Z080-1", "name": "", "aln": "---MPRSHFTRRHCLAMT--GGLIASAVIIWCVAHSTVES---------TAKLYD--PGADKSTLELLHVVFRHGPRTPADTYPRDPY--VNETYYPFGWGQITNNGKRELFNIGTWLRKRYGKFLAPN--YSPDSVHAQATGVPRTHMTMQTVLAAFFPPKGTDMEWNSRFNWQPIPVFSQELNEDTLLLV-RKPCPRYFEALNEVYELP--EVKAEIEPYLEMFKELEEHTGLSFK--EPEDVQSLYLTLLAEQEWGLELPEWTHAYFP---EKLQFLAEQSYIYNVYTPEMQKIKGGPFLKKMLDEMQQKKNGTLKPSGRKLFIYAGHDSTVVNVLSALKIWER--QMPRYSSMILFELHKNK------ETGDYWVEIYFR-NDPKGQAQKLTLPGCEFQCPLDKVLEFAKDVVPTEADDKRCESRNEAFTEPPLRGP----------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VW01-1", "uniprot_id": "Q9VW01_DROME", "id": "Q9VW01-1", "name": "Acid phosphatase", "aln": "---MIFARWTRKQMLTMFGLGAGLLGLVIVIGVLNSGVSSKDLDWKEASRSKCFKTRPNTTHSTLELVHIVFRHGIRTPVDTYPKDPY--LNDGFKPTGWGHVTNSGKRELFEMGRWLNRRYGEFMGPY--YRPDRLHAQATASPRAMMSLQTTLASMFEPRGTPMEWNKHLNWQPIPIVSEPLDEDSLLLV-RTPCPRYFEALEEVFKRP--EVIAETEPYEQMFRELTNLTGKAIQ--SAEDINSLYITLLAEQEFGYKLPDWAKDYFP---DRMQFLAEQSYVYNAYTPEMQKIKGGPFLKRMYKEMVAKRAGSLKPKDRGMFIYTGHDWTVGNILMALGVWKR--QMPRFAVMAIFETHRDK------ETGEYYVEIFLR-NDEDGCLEQLQLKDCDRRCPLDRLIKLSADVLPTEPAEQRCRPHDSNFVEPPPRVIDQNGR-----------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VW00-1", "uniprot_id": "Q9VW00_DROME", "id": "Q9VW00-1", "name": "", "aln": "-MRKFLGLLLTVSCVLIARGGVMEIEVPQEVTEGPGDVSQ--------SSAEISHAKDSVSNSTLKLVHVLFRHGPRTPVSTYPNDPY--INETYEPFGWGALTNGAKVELYKIGKQLRQRYKDFLPAY--YQPDAIRAQSSESPRTLMSMQMVLAGLFPPENTPMEWNQLLNWQPIPIVMEPEETDVHIRM-KAPCPRYDESVLEVIELP--EVKKLHAESSDLLRELTTHTGLNIT--HAHDVTNVFITLLCEQTFGLQLPSWTNDYFP---EKMLPLAEKSYVYDAYTTEQRKMKGGFFVELLLKQMQDRISGALKPANRKMFLSCGHDWTITNVLSALNVWEA--QMPRFSSLIAFELHQNP------QTGEYFLEIYFQ-NDPHKEPQQLQIPGCEKQCPIGKLLELTKDIIPDAPYAELCKAKG---TQGGAKISYH--------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VD68-1", "uniprot_id": "Q9VD68_DROME", "id": "Q9VD68-1", "name": "Acid phosphatase", "aln": "----MDCKSRRGTKISVIALGSALCFVMMAYFVFGDSNDE-------------------QGLRNLRMISILFRHGAKNPSGFYPLDPH--AAHDWQG-GMGALTPKGSLQAYNLGRNLRMRYYRLLPPNSLYTQQQVNVLSSAAERCVMSAQSVLAGMMPP--LENKNVLPIPWQPVAVNTLSRNEDILLAQ-KKPCLKYDHILQKLYKSPPPELQKLNEDNMELYKLLTKNTGKNIS--NVLDVELLYGTLKTEEEANLVLPDWTENIYP---EEIRPLAERSYMLFTETNLMKRIKGGAFLTDILNKMQNKRKRNLNP-DRKIFLYSGHDVTLVNVMNSLGILDQTTKLPEYASALAFELHHSKS----FSDGDFEVKLVYYYNSEDKFPKELTIPNCDAPCSLTQFEASVKALLLDN-YDETCENHPTDCKT----------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9BZG2-1", "uniprot_id": "PPAT_HUMAN", "id": "Q9BZG2-1", "name": "Testicular acid phosphatase", "aln": "---------MAGLGFWGHPAGPLLLLLLLVLPP------------------------RALPEGPLVFVALVFRHGDRAPLASYPMDPHKEVASTLWPRGLGQLTTEGVRQQLELGRFLRSRYEAFLSPE--YRREEVYIRSTDFDRTLESAQANLAGLFPEAAPGSP---EARWRPIPVHTVPVAEDKLLRFPMRSCPRYHELLREATEAA--EYQEALEGWTGFLSRLENFTGLSLVGEPLRRAWKVLDTLMCQQAHGLPLPAWASPDVLRTLAQISALDIGAHVGPPRAAEKAQLTGGILLNAILANFSRVQR---LGLPLKMVMYSAHDSTLLALQGALGLYDG--HTPPYAACLGFEFRKHLGNPAK-DGGNVTVSLFYR-NDSAHLPLPLSLPGCPAPCPLGRFYQLTAPARPPAHGVSCHGPYEAAIPPAPVVPLLAGAVAVLVALSLGLGLLAWRP------------------------------------------------GCLRALGGPV--------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3YTS9-1", "uniprot_id": "PPAT_MOUSE", "id": "D3YTS9-1", "name": "Testicular acid phosphatase", "aln": "---------MAEPGSQGHTVGPLLLLLLLLLP-------------------------RALPEGPLLFVALVFRHGDRAPLASYPTDPHKEAASTLWPRGLGQLTKEGIRQQLELGRFLRRRYKAFLSPE--YKREEVYIRSTDFDRTLESAQANLAGLFPEAAPGSP---ETDWKPIPVHTVPVSEDKLLRFPMRSCPRYHELLRESTEAA--DYQEALEGWTDFLTRLGNFTGLSLVGEPLRRAWKVLDTLICQRAHGLDLPSWASPDVLRTLSQISALDIRAHVGPPRAAEKAQLTGGILLDAILSNFSRTQR---LGLPLKMVMYSAHDSTLLALQGALGLYDG--NTPPYAACMAFEFRGSSREPEEEDGENVTVSLIYR-NDTSRPPLPLRVPGCPAPCPLGRFQQLTAPARPPAHGAPCHGSYEPASPPA-TVPLLAGAVAVLAVLSLGLGLLAWRP------------------------------------------------RCLRALGGTV--------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GH32-1", "uniprot_id": "A0A8I6GH32_RAT", "id": "A0A8I6GH32-1", "name": "acid phosphatase", "aln": "---------------MHHWRSPVLCSVLRLET-----------------------------QG----TYMVFRHGDRAPLASYPTDPHKEAASTLWPRGLGQLTKEGIRQQLELGRFLRRRYKAFLSPE--YRREEVYIRSTDFDRTLESAQANLAGLFPEAAPGSP---EADWKPIPVHTVPVSEDKLLRFPMRSCPRYHELLRESTEAA--DYQEALEGWTDFLTRLGNFTGLSLVGEPLRRAWKVLDTLICQRAHGLALPSWASPDVLRTLSQISALDIRAHVGPPRAAEKAQLTGGILLDAILSNFSRAQR---LGLPLKMVMYSAHDSTLLALQGALGLYDG--NTPPYAACMAFEFRGSSREPEEEDGENVTVSLIYR-NDTSRPPLPLRVPGCPAPCPLGRFQQLTAPARPPAHGAPCHGSYEPASPPDRWSILWKQAKGGQVRLCLTCPGPSSSPRFYPRRDRIKQHTPQRAMIQPFNRNSRRQKFQGCPPHPSTKSRSTLARGHLCSQGDQTQLEGASRGKGMVKRKWGQGPQSKVFTKGGSPPHKKVSHKLKIKYKVKMLH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8I0P9-1", "uniprot_id": "Q8I0P9_DROME", "id": "Q8I0P9-1", "name": "acid phosphatase", "aln": "MFSRSRCGSLVTSVARKMWNHPSQRWLILICVICLLSFALANSLHGYANAEGHPVEISATLPGQLKFVHVIYRHGDRTPVDPYPTDPWG--DRKFWPTGWGDLTNLGKQEHYDLGKWLRNRYSNLLPPI--YSNENIYVQSTDVDRTLMSAQSNLAGLYEPQGEDIWN-TDINWQPIPIHTSPEREDPILAA-KAPCPAYDYELASLESSP--EFKALTEKHRNLFAYLSEKGGRPVK--TFIDAQYLNNTLFIENLYNMTLPKWTKMVYGR--EELTYVSNFAFAISSYTRKLARLKAGPLLKDIFQRFKEKSSGSLKP-DRSMWVYSAHDTTVASVLNALKLFEL--HSPPYTACIMMELRVDET-------NTPLVSIFYK--NTTAEPLPLDIPGCGPSCPLTKLMNIYEDVLPVDWERECKLSTMMMTYEEANLGTATGILILIVIALLFASYGLMIYYRRRNYKLYSSYSQMA--------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :::*** : * ** ** * * :* . : .:* *. ** :: . * : : :: * : * **.: *:*:.: * : .* * : . . . : : * * . : ** :. . ** *: .: : :. : ::..* :: : .: : : .** *: : :* : . : * :: :* : :.: . * : .* *.: :. ", "identical_positions": 42, "similar_positions": 76, "identity": "7.36%" }, { "cls_id": "homologset.agr.RGD:1308272", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M6YZP6-1", "uniprot_id": "A0A8M6YZP6_DANRE", "id": "A0A8M6YZP6-1", "name": "non-specific serine/threonine protein kinase", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MERKVLALQARKKRAKAK----KSTKKPAHPPRGASQQQP----------------PPTETQIQEPD---EEILG----------------------------------------------------------------------------SDDEEQEDPNDYCKGGYHHVKIGDLLN-SKYHVIRKLGWGHFSTVWLAWDIQGKRFVAMKVVKSAEHYTETALDEIKLLRSVRNTD---PDDPNREMVVQLLDDFKISGVNGTHVCMVFEVLGHHLLKWIIKSNYQGLPLPCVKSIIRQVLQGLDYLHTKCQIIHTDIKPENILMSVEELYVRRLAAEATEWQKAGAPPPSGSAVSTAP----APKQAPKMSKNKKKKLKKKQKRQAELLEKCIMDLEEMEI--GPEGREEE-EDDPESPKS-----PSCAPLRQASLQEIATEDIIMDTRERLTSDASVELN--CNGCLHSSKTQPEEDEQGDLQYGQLLQEDHHNANAGPEDTAQSMYEY--CNGAESPELDQACYSNG------TSGQEQ-----LEDGELATEEQH------QQKTRTRAREQNKDKIKD-DKLSAG----SLLVNPLDP------------LNADKIKVKIADLGNACWVHKHFTEDIQTRQYRSLEVLLGSGYNTPADIWSTACMAFELATGDYLFEPHSGEDYSRDEDHLALIIELLGHIPRHYALSGKFSQEYFCRKGDLKHITKLKPWGLLDVLMDKYEWPQEEAQTFSDFLLPMLELLPEKRATASDCLRHPWLAL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8N7UYM5-1", "uniprot_id": "A0A8N7UYM5_DANRE", "id": "A0A8N7UYM5-1", "name": "non-specific serine/threonine protein kinase", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MERKVLALQARKKRTKTK----KPGKKPDPHPRGAAQQP---------------------DALQEQD---EEILG----------------------------------------------------------------------------SDDEEQEDPNDYCKGGYHHVKIGDLFN-GRYHVIRKLGWGHFSTVWLAWDTQGKRFVAMKVVKSAEHYTETALDEIKLLKAVRNTD---QNDPSREKVVQLLDDFKISGVNGTHVCMVFEVLGHHLLKWIIKSNYQGLPLPCVKSIIRQVLQGLDYLHTKCKIIHTDIKPENILMDVNEAYVKRLAAEATEWQKSGAPPPSGSAVSTAP----APKQATKMSKNKKKKMKKKQKRQAELLEKRILEIEGLEK--GLDGGEEEDEDETETPDS-----TPSVPS-SHTLQDISTETTLDGTSEAWS---QVTGS--VNGHIPS----PEDEQSLDVQQ-QMKDETPVNPYDSGNETSEPTNPYPACNGTEETEPSPACLSAADGNGALISGMVESQGCRVQDGESLTAELKDPRAEMEAEPGTQAVPEEEESLKD-AKTAAG----NLLVNPLEP------------LNAEKIQVKIADLGNACWVHKHFTDDIQTRQYRSLEVLIGTGYGTPADIWSTACMAFELATGDYLFEPHSGEDYSRDEDHIALIIELLGKIPRKLVMNGKYSKEFFTKKGDLRHITKLKPWGLQDVLVEKYEWHREEAQNFSDFLLPMLDLIPEKRATAAECLRHSWINS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O70551-1", "uniprot_id": "SRPK1_MOUSE", "id": "O70551-1", "name": "SRSF protein kinase 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MERKVLALQARKKRTKAKK--DKAQRKPETQHRGSAPHS--------------------ESDIPEQE---EEILG----------------------------------------------------------------------------SDDDEQEDPNDYCKGGYHLVKIGDLFN-GRYHVIRKLGWGHFSTVWLSWDIQGKKFVAMKVVKSAEHYTETALDEIRLLKSVRNSD---PNDPNGEMVVQLLDDFKISGVNGTHICMVFEVLGHHLLKWIIKSNYQGLPLPCVKKIIQQVLQGLDYLHTKCRIIHTDIKPENILLSVNEQYIRRLAAEATEWQRSGAPPPSGSAVSTAP----QPKPADKMSKNKKKKLKKKQKRQAELLEKRMQEIEEMEKESGPGQKRPNKQEESESPVDRPLTENPPNKMTQEKLEESNSIGQDQTLTERGGEGGAPEIN--CNGVIGVVNYPENSNNETLRHKEDLHNANDCDVHTLKQEPSFLNSSNGDSSPSQDTDSCTPTAS---ETMVCQSSAEQS--LTRQDITQLEESIR-----ADTPSGDEQEP--NGALDSKGKFSAG----NFLINPLEP------------KNAEKLQVKIADLGNACWVHKHFTEDIQTRQYRSLEVLIGSGYNTPADIWSTACMAFELATGDYLFEPHSGEDYTRDEDHIALIIELLGKVPRKLIVAGKYSKEFFTKKGDLKHITKLKPWGLLEVLVEKYEWPQEEAAGFTDFLLPMLELMPEKRATAAECLRHPWLNS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4KLN3-1", "uniprot_id": "Q4KLN3_RAT", "id": "Q4KLN3-1", "name": "SRSF protein kinase 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MERKVLALQARKKRTKAKK--DKAQRKPETQHRGSAPHS--------------------ESDIPEQE---EEILG----------------------------------------------------------------------------SDDDEQEDPNDYCKGGYHLVKIGDLFN-GRYHVIRKLGWGHFSTVWLSWDIQGKKFVAMKVVKSAEHYTETALDEIRLLKSVRNSD---PNDPNGEMVVQLLDDFKISGVNGTHICMVFEVLGHHLLKWIIKSNYQGLPLPCVKKIIQQVLQGLDYLHTKCRIIHTDIKPENILLSVNEQYIRRLAAEATEWQRSGAPPPSGSAVSTAP----QPKPADKMSKNKKKKLKKKQKRQAELLEKRMQEIEEMEKESGPGQKRPNKQEESESPVERPLTENPPNKMTQEKLEESSSIGQDQTLTEHGGEGGAPEIN--CNGVIGIVNYTANSNNETLRLKEDLHNANDCDGRTLKQEPSFLSSPNGDSSPSPETDSCTPSGSEVPETMACQASVERSLTLTQQDITHLQERIR-----AHTPSGDEQEREHNGALDSKGKFSAG----NFLINPLEP------------KNAEKLKVKIADLGNACWVHKHFTEDIQTRQYRSLEVLIGSGYNTPADIWSTACMAFELATGDYLFEPHSGEDYTRDEDHIALIIELLGKVPRKLIVAGKYSKEFFTKKGDLKHITKLKPWGLLEVLVEKYEWPQEEAAGFTDFLLPMLELMPEKRATAAECLRHPWLNS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96SB4-2", "uniprot_id": "SRPK1_HUMAN", "id": "Q96SB4-2", "name": "SRSF protein kinase 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MERKVLALQARKKRTKAKK--DKAQRKSETQHRGSAPHS--------------------ESDLPEQE---EEILG----------------------------------------------------------------------------SDDDEQEDPNDYCKGGYHLVKIGDLFN-GRYHVIRKLGWGHFSTVWLSWDIQGKKFVAMKVVKSAEHYTETALDEIRLLKSVRNSD---PNDPNREMVVQLLDDFKISGVNGTHICMVFEVLGHHLLKWIIKSNYQGLPLPCVKKIIQQVLQGLDYLHTKCRIIHTDIKPENILLSVNEQYIRRLAAEATEWQRSGAPPPSGSAVSTAP----QPKPADKMSKNKKKKLKKKQKRQAELLEKRMQEIEEMEKESGPGQKRPNKQEESESPVERPLKENPPNKMTQEKLEESSTIGQDQTLMERDTEGGAAEIN--CNGVIEVINYTQNSNNETLRHKEDLHNANDCDVQNLNQESSFLSSQNGDSSTSQETDSCTPITSEVSDTMVCQSSSTVGQSFSEQHISQLQESIR-----AEIPCEDEQEQEHNGPLDNKGKSTAG----NFLVNPLEP------------KNAEKLKVKIADLGNACWVHKHFTEDIQTRQYRSLEVLIGSGYNTPADIWSTACMAFELATGDYLFEPHSGEEYTRDEDHIALIIELLGKVPRKLIVAGKYSKEFFTKKGDLKHITKLKPWGLFEVLVEKYEWSQEEAAGFTDFLLPMLELIPEKRATAAECLRHPWLNS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A6M3Q7C8-1", "uniprot_id": "A0A6M3Q7C8_DROME", "id": "A0A6M3Q7C8-1", "name": "non-specific serine/threonine protein kinase", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNKADVNRRVLAIQAKKKRHKNRKRGKQNGTNPQEQSNSSQNQNP----------------KPSSNPIPEPNRSSENLQAPDNANNSHLNAPSSAAFSKATATATASTSSGGSAGTPDQYQPPKKTQAKAKPNTQKEHQQQPPRSSSNESYESETFSDNEDQELMEDYCKGGYHPVNIGDLFH-DRYHVIRKLGWGHFSTVWLCWDLQAMGYVAIKIVKSAPHFAETARDEIKILKTVRETD---PSNPRRHKTVQMLDDFKITGVNGTHICMVFEVLGDNLLKLIRKSNYRGIPLANVKTITRQVLEGLDYLHTCCKIIHTDIKPENVLLCVDEPHVRSLATEATQLYCMNSKMYP-SLVSRAPKEYREPPITGKMSKNRKKKLKKKAKKRMELFKQQRDYLEQADGQGAINPNEVQNGDAGISDADEYFDANSVEDNVHVAAGQPSRKQREERKAPPEQSEEAQEQDPLTEGTDKAKKKKKKKNKNKSNQSKGQQPPQLENSTSSAESSSALKSQQANGSNSTTNNKSNTNSSGTLKGQSNGKKMPLRPKQEKQGSNHQLNNNN------SKPNSNSDSKISSGSVENTSSATNGPHSNSTLPTPPPPPQAKHKAKKDPALDECNVHVKIADLGNACWVDRHFTEDIQTRQYRSLEVIIGAGYNTSADIWSTACMVFELATGDYLFEPHSGESYTRDEDHLAHIIELLGPIPREILLNGTYAAKSFTRSCELRNISGLKPWGLMDVLLEKYEWSQKDAASFASFLTPMLEFDPNKRATAAECLQHPWLRXDTMQPGCWLRATQPATADGDGGALAGTGTGKGTRARATALKGGSPAVPADGEVGRGYIESSASVATLASISSIASTSAAAMAALKARPYLVAPFVTTASAPPTPHPHASISTSTARTAPATPTRRRIAPEDDLNLVEDLDVALAQIEDTQTHTKNKSQRFFWRKALRRVFQRRKXRRRRQDLPRWHRPARRCRRRNLAERVRRICACCAYGQILLRAARVALLSCIRWRTRGNIRNNNFYFSNH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "M9MS50-1", "uniprot_id": "SRPK7_DROME", "id": "M9MS50-1", "name": "Serine-arginine protein kinase at 79D", "aln": "MAGLIGAANGKHHHPHLISPTHTSLPAGICSSDSGISTLSAISPPLSTSTTTASGAGGGVGGSPQLRTSPALSMLGSATATASGVTASSGCGLTAGILGPAASIDLGSSPLSHRNYSNSLKGFSFRRSFDDKIINTPYLSRAPAYTHGIPYPHFHGTQPAATTPHHLHLHHHGNGTAAGSGSGVGSGPGSGSGAGGLYQQPLSLASMTAALPLAPLYGSPLSLPLTSSQSTTKLSYRDDFLQQIGYLPTTRIYSTPTSIVDEDKAQQDFLSLSLSPPLNRRRDMPALRG------------------------------PFVSLSEPRGTLSTTDEIYPDSSDSSLYVSDEEQEDASQYCRGGYHPVVIGDIFD-NRFRVVRKLGWGHFSTVWLCRDLKDEKYVALKVVKSAPHYIETAADEIRLLEAIRDAD---PMDVKRERIVRLMNHFTVRGVNGMHTCLVFEALGCSLYKLIVKNNYQGLAIAQVRNIIRQVLEGLDYLHSKCSIIHTDIKPENILLVIDN--------------------------------------AAAMNQQIDDEINSLRVKGVDFPDSYISSIEKQTKSRAKWPLIEPNGSTNTNTNTSNSTATNSNSSTPLAAVIMSTLDKEDTTTTTSSTLNSNTTS--SLASKYSSLLGDSECNGGLGGSANINNRYRTEKKITAKSSGDCDEDAESDTLGEQSTLASTMDSPT-----------------DLDPEPELDSKP-----------NTVPEPSEGPIPENQSQSSQ-----NNTYTIQS-----------LIDNSNVRVKIADLGNACYDYHHFTEDIQTRQYRSIEVLLGAPYNYTADIWSTACLAFELATGDYLFDPHAGESYSRDEDHLAHIVELLGSIPQSVIFRGKHGLKYFTSYGSLRNITKLKPWSLMNVLVEKYDWDPVEAKKFSDFLLPMLEYNPVIRASAAECLQHPWLEQEEFV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03656-1", "uniprot_id": "SKY1_YEAST", "id": "Q03656-1", "name": "Serine/threonine-protein kinase SKY1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------MGSSINYPGFVTKSAHLADTSTDASISCEEATSSQEAKKNFFQRDYNMMKKAPAPTKSKLSLALQTSKSSSSANGTVQEDTS----------SKTEDFSTKSIKKKPDSGVESHVSIQSDSGPQSDSDLDSDSS-------------------------------------------------------ISSCDERNEESLKDYRPGGYHPAFKGEPYKDARYILVRKLGWGHFSTVWLAKDMVNNTHVAMKIVRGDKVYTEAAEDEIKLLQRVNDADNTKEDSMGANHILKLLDHFNHKGPNGVHVVMVFEVLGENLLALIKKYEHRGIPLIYVKQISKQLLLGLDYMHRRCGIIHTDIKPENVLMEIGDVEGIVQMVEALDKQKREAKRLQRHVSRSSD------ITANDSSDEKWAECQTSMPCGSSSNSKSRSIEKDLSKRCFRRPRRHTIITGSQPLPSPISSSNFFEMRAHFCGSSHNSFSSVSGNRNIPSSINNNSIN---NGIGIKNSNNSFLNSVPHSVTRMFINEDSNDNNNNDNSKNKNNNNNNSNNNNNEDIMNTPLHEEQ-----------------LADSLSTFDISN-----------ISQSSDTNGPYISNTMDSNS-----NVSTDINS-------------PENLIQIKIADLGNACWYDEHYTNSIQTREYRSPEVLLGAPWGCGADIWSTACLIFELITGDFLFEPDEGHSYTKDDDHIAQIIELLGELPSYLLRNGKYTRTFFNSRGLLRNISKLKFWPLEDVLTEKYKFSKDEAKEISDFLSPMLQLDPRKRADAGGLVNHPWLKDTLGMEEIRVPDRELYGSGSDIPGWFEEVRDHKRH------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : . ..: . : :. . .: ::* .:* **** . *: . :: ::*************. * .**:*:*:. : *:* ***::*. :.::* . . :::::.*. * ** * :***.** * * * :::*:.: *: * :*:* ****:* * **********:*: : : : ..: : :. . .. : . . . : :. . . . . . : . :::*********: .*:*:.****:*** **::*: :. ********: *** ***:**:*. *..*::*:**:* *:**** :* *.. * *::*: ** * * :** :**.: :* ::.** ***: * ** *. :.*.*: ", "identical_positions": 141, "similar_positions": 134, "identity": "11.49%" }, { "cls_id": "homologset.agr.RGD:1308273", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q99NB8-1", "uniprot_id": "UBQL4_MOUSE", "id": "Q99NB8-1", "name": "Ubiquilin-4", "aln": "MAEPSGAETRPQIRVTVKTPKDKEEIVICDQASVKEFKEEISRRFKAQQDQLVLIFAGKILKDGDTLSQHGIKDGLTVHLVIKTPQKAQDPVTAAASPPSTPDSASAPSTTPASPAAAPVQPCSSGNTTSDAGSG------GGPSPVAAEGPSSATASILSGFGGILGLGSLGLGSANFMELQQQMQRQLMSNPEMLSQIMENPLVQDMMSNPDLMRHMIMANPQMQQLMERNPEISHMLNNPELMRQTMELARNPAMMQEMMRNQDRALSNLESVPGGYNALRRMYTDIQEPMFTAAREQFGNNPFSSLA--GNSDNSSSQPLRTENREPLPNPWSPSPPTSQAPGSGGEGTGGSGTSQVHPTVSNPFGINAASLGSGMFNSPEMQALLQQISENPQLMQNVISAPYMRTMMQTLAQNPDFAAQMMVNVPLFAGNPQLQEQLRLQLPVFLQQMQNPESLSILTNPRAMQALLQIQQGLQTLQTEAPGLVPSLGS--------FGTPRTSVPLAGSNSGSSAEAPTSSPGVPATS-PP---SAGSNAQQQLMQQMIQLLSGSGN--SQVPMPEVRFQQQLEQLNSMGFINREANLQALIATGGDINAAIERLLGS-QLS--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A3P1-1", "uniprot_id": "D4A3P1_RAT", "id": "D4A3P1-1", "name": "Ubiquilin-4", "aln": "MAEPSGAETRPQIRVTVKTPKDKEEILICDQASVKEFKEEISRRFKAQQDQLVLIFAGKILKDGDTLNQHGIKDGLTVHLVIKTPQKAQDPVTTTASSPSTPDSASAPSTTPASP-AAPVQPCSSGNTTSDASSG------GGPSPVAAEGPSNATASILSGFGGILGLGSLGLGSANFMELQQQMQRQLMSNPEMLSQIMENPLVQDMMSNPDLMRHMIMANPQMQQLMERNPEISHMLNNPELMRQTMELARNPAMMQEMMRNQDRALSNLESVPGGYNALRRMYTDIQEPMFTAAREQFGNNPFSSLA--GNSDNSSSQPLRTENREPLPNPWSPSPPTSQAPGSGGEGTGGSGTSQVHPTVSNPFGINAASLGSGMFNSPEMQALLQQISENPQLMQNVISAPYMRTMMQTLAQNPDFAAQMMVNVPLFAGNPQLQEQLRLQLPVFLQQMQNPESLSILTNPRAMQALLQIQQGLQTLQTEAPGLVPSLGS--------FGTPRTSVPLAGSNSGSAAEAPTASPGTPATT-PP---SAGSNTQQQLMQQMIQLLSGSGN--SQVPVPEVRFQQQLEQLNSMGFVNREANLQALIATGGDINAAIERLLGS-QLS--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NRR5-1", "uniprot_id": "UBQL4_HUMAN", "id": "Q9NRR5-1", "name": "Ubiquilin-4", "aln": "MAEPSGAETRPPIRVTVKTPKDKEEIVICDRASVKEFKEEISRRFKAQQDQLVLIFAGKILKDGDTLNQHGIKDGLTVHLVIKTPQKAQDPAAATASSPSTPDPASAPSTTPASP-ATPAQPSTSGSASSDAGSGSRRSSGGGPSPGAGEGSPSATASILSGFGGILGLGSLGLGSANFMELQQQMQRQLMSNPEMLSQIMENPLVQDMMSNPDLMRHMIMANPQMQQLMERNPEISHMLNNPELMRQTMELARNPAMMQEMMRNQDRALSNLESIPGGYNALRRMYTDIQEPMFSAAREQFGNNPFSSLA--GNSDSSSSQPLRTENREPLPNPWSPSPPTSQAPGSGGEGTGGSGTSQVHPTVSNPFGINAASLGSGMFNSPEMQALLQQISENPQLMQNVISAPYMRSMMQTLAQNPDFAAQMMVNVPLFAGNPQLQEQLRLQLPVFLQQMQNPESLSILTNPRAMQALLQIQQGLQTLQTEAPGLVPSLGS--------FGISRTPAPSAGSNAGSTPEAPTSSPATPATS-SP---TGASSAQQQLMQQMIQLLAGSGN--SQVQTPEVRFQQQLEQLNSMGFINREANLQALIATGGDINAAIERLLGS-QLS--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VWD9-1", "uniprot_id": "Q9VWD9_DROME", "id": "Q9VWD9-1", "name": "Ubiquilin-like protein", "aln": "MAE--GGSKR--INVVVKTPKDKKTVEVDEDSGIKDFKILVAQKFEAEPEQLVLIFAGKIMKDTDTLQMHNIKDNLTVHLVIKAPTRNNE----------------QPARQPADVRQTPFG--------------------------------------LNQFGGLAGMEALGAGSNTFMDLQARMQNELLNNGDMLRSLMDNPMVQQMMNNPDTMRQLITSNPQMHDLMQRNPEISHMLNNPDLLRQTMELARNPSMLQELMRSHDRAMSNLESVPGGYSALQRIYRDIQEPMMNAATESFGRNPFAGLVDGGGSGAGNNPQQGTENRNPLPNPWG-------GANSGTNGTVG-GSGAGNPTGDLPP--------NNVLNTPAMRSLLQQMADNPAMMQNLLNAPYTRSMMESMSQDPDMAARLLSSSPLMSNNPALQEQVRQMMPQFMAQMQNPEVMNMLTNPDAMNAILQIQQGMEQLRSAAPGLVGTLGIPPPPPGAGTGTNPASGDGSGGNSGASTNNVSPSSGLNAGTGTPNLAPGGGPNAQLFNDFMMRMLNGMSNNADNTQPPEVRYQSQLEQLNAMGFVNRDANLQALIATFGDINAAVERLLSLNQLSLS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P48510-1", "uniprot_id": "DSK2_YEAST", "id": "P48510-1", "name": "Ubiquitin domain-containing protein DSK2", "aln": "----------MSLNIHIKSGQDKWEVNVAPESTVLQFKEAINKANGIPVANQRLIYSGKILKDDQTVESYHIQDGHSVHLVKSQPK-------------------PQTASAAG------------------------------------------------ANNATATGAAAGTGATPNMSSGQSAGFNPLADLTSARYAGYLNMPSADMFGPDGG--------ALNNDSNNQDELLRMMENPIFQSQMNEMLSNPQMLDFMIQSNP------------------------------------------------------------------------------------------------------------------QLQAMGPQARQMLQSP--------------MFRQMLTNPDMIRQSMQFARMMDPNAGMGSAGGAASAFPAPGGDAPE------------------EGSNTNTTSSSNTGNNAGT-------------NAGTNAGANTAANPFASLLNPALNPFANAGNAASTGMPAFDPALLASMFQPPVQASQAEDTRPPEERYEHQLRQLNDMGFFDFDRNVAALRRSGGSVQGALDSLLNGDV----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.: :*: :** : : : : :** : : : **::***:** :*:. : *:*. :**** . * .: .. .. : * *: *. : : : : . * .** ::: :.: *: :*::** : * *: ** *:: :::.: : * . :*: :.* *:. : :**: : : :: *. : . . : ** :* : : :.. . * . :*.*:.: . ... . : . . . : : .. .:. ** *:: **.*** ***.: : *: ** : *.::.*:: **. ", "identical_positions": 66, "similar_positions": 123, "identity": "10.63%" }, { "cls_id": "homologset.agr.RGD:1308275", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZDP9-1", "uniprot_id": "D3ZDP9_RAT", "id": "D3ZDP9-1", "name": "Zinc finger and BTB domain-containing protein 11", "aln": "MSSEESYRAILRYLTNEREPYAPGTEGNVKRKIRKAAACYVVRGGTLYYQRRQRHRKTFAELEVVLQPERRQGLIEAAHLGPGGTHHTRHQTWHDLSKTYWWRGILKQVKDYIKQCSKCQEKLDRSRPISDASEMLEELGLDLESGEESNESEDDLSNFTSPPTTASKTSKKKPVSKHELVFVDTKGVVKRSSPKHCQAVLKQLNEQRLSNQFCDVTLLIEGEEYKAHKSVLSANSEYFRDLFIEKGAVSSHEAVVDLSGFCKASFLPLLEFAYTSVLSFDFCSMADVAVLARHLFMSEVLEICESVHKLMEEKQLTVYKKGEVQTVASTQDLAAHNGAATPPGPRNEATTT-LSSDLGHCEIVLLVNGEVPETEQNGEPGQQPAPQVSAEAEASVSPAGCIPNPPTEMGAASLATESNQPELESAVVREDGGVASVPPKISEENVINTSQEDSDIGNDTSPEDTCTKDFSDHSQSSGQPLKDEETLIEATEKTDSGQDDDTYRSRLRQRSVNEGGYIRLHKGMEKKLQKRKAISKSAVQQVAQKLVQRGKKMKQPKRDAKESAEETPHKCGECGMVFPRRYAFIMHTLKHERARDYKCPLCKKQFQYSASLRAHLIRHTRKDAPTSSSSNSTSNEASGASSEKGRTKREFICSICGRTLPKLYSLRIHMLKHTGVKPHACQVCGKTFIYKHGLKLHQSLHQSQKQFQCELCVKSFVTKRSLQEHMSIHTGESKYFCSVCGKSFHRGSGLSKHLKKHQPKPEVRGYHCTQCEKSFFEARDLRQHMNKHLGVKPFQCQFCDKCYSWKKDWYSHVKSHSVTEPYRCNICGKEFYEKALFRRHVKKATHGKKGRAKQNLERVCDQCGRKFTQLREYRRHMNNHEGVKPFECLTCGVAWADARSLKRHVRTHTGERPYVCPVCSEAYIDARTLRKHMTKFHRDYVPCKIMLEKDTLQFHNQGTQVEHAVSILTADMQEQESSGPQELETVVVTGETMEVLEAVAATEECPSVSTLSDQSIMQVVNYVLAQQQGQKLSEVAEAIQTVEVEVAHMPEAE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "G5E8B9-1", "uniprot_id": "ZBT11_MOUSE", "id": "G5E8B9-1", "name": "Zinc finger and BTB domain-containing protein 11", "aln": "MSSEESYRAILRYLTNEREPYAPGTEGNVKRKIRKAAACYVVRGGTLYYQRRQRHRKTFAELEVVLQPERRQGLIEAAHLGPGGTHHTRHQTWHDLSKTYWWRGILKQVKDYIKQCSKCQEKLDRSRPISDASEMLEELGLDLDSGEESNESEDDLSNFTSPPSTASKSSKKKPVSKHELVFVDTKGVVKRSSPKHCQAVLKQLNEQRLSNQFCDVTLLIEGEEYKAHKSVLSANSEYFRDLFIEKGAVSSHEAVVDLSGFCKASFLPLLEFAYTSVLSFDFCSMADVAVLARHLFMSEVLEICESVHKLMEEKQLTVYKKGEVQTVASTQDLAAHNGTTTPPGTRNEATTT-LSGELGHCEIVLLVNGELPEAEQNGEPEQQPAPQASPEAEASVSPVEGIPEPHPEMGTASLAKESNQP--ESAVTREDGIVASVHPKISKENVTNASQEDSDTGNDTSPEDIGAKDCPDHSQSPGQPSKDEDTLTEATEKTDSGPDDDTYRSRLRQRSVNEGGYIRLHKGMEKKLQKRKAISKSAVQQVAQKLVQRGKKMKQPKRDAKESTEETAHKCGECGMVFPRRYAFIMHTLKHERARDYKCPLCKKQFQYSASLRAHLIRHTRKEAPTSSSSNSTSTEASGGSSEKGRTKREFICSICGRTLPKLYSLRIHMLKHTGVKPHACQVCGKTFIYKHGLKLHQSLHQSQKQFQCELCVKSFVTKRSLQEHMSIHTGESKYFCSICGKSFHRGSGLSKHLKKHQPKPEVRGYHCTQCEKSFFEARDLRQHMNKHLGVKPFQCQFCDKCYSWKKDWYSHVKSHSVTEPYRCNICGKEFYEKALFRRHVKKATHGKKGRAKQNLERVCDQCGRKFTQLREYRRHMNNHEGVKPFECLTCGVAWADARSLKRHVRTHTGERPYVCPVCSEAYIDARTLRKHMTKFHRDYVPCKIMLEKDTLQFHNQGTQVEHAVSILTADMQEQESSGPQELETVVVTGETMEVLEAVAATEECPSVSTLSDQSIMQVVNYVLAQQQGQKLSEVAEAIQTVEVEVAHMPEAE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95625-1", "uniprot_id": "ZBT11_HUMAN", "id": "O95625-1", "name": "Zinc finger and BTB domain-containing protein 11", "aln": "MSSEESYRAILRYLTNEREPYAPGTEGNVKRKIRKAAACYVVRGGTLYYQRRQRHRKTFAELEVVLQPERRRDLIEAAHLGPGGTHHTRHQTWHYLSKTYWWRGILKQVKDYIKQCSKCQEKLDRSRPISDVSEMLEELGLDLESGEESNESEDDLSNFTSSPTTASKPAKKKPVSKHELVFVDTKGVVKRSSPKHCQAVLKQLNEQRLSNQFCDVTLLIEGEEYKAHKSVLSANSEYFRDLFIEKGAVSSHEAVVDLSGFCKASFLPLLEFAYTSVLSFDFCSMADVAILARHLFMSEVLEICESVHKLMEEKQLTVYKKGEVQTVASTQDLRVQNGGTAPPVASSEGTTTSLPTELGDCEIVLLVNGELPEAEQNGEVGRQPEPQVSSEAESALSSVGCIADSHPEMESVDLITKNNQTELETSNNRENNTVSNIHPKLSKENVISSSPEDSGMGNDISAEDICAEDIPKHRQKVDQPLKDQENLVASTAKTDFGPDDDTYRSRLRQRSVNEGAYIRLHKGMEKKLQKRKAVPKSAVQQVAQKLVQRGKKMKQPKRDAKENTEEASHKCGECGMVFQRRYALIMHKLKHERARDYKCPLCKKQFQYSASLRAHLIRHTRKDAPSSSSSNSTSNEASGTSSEKGRTKREFICSICGRTLPKLYSLRIHMLKHTGVKPHACQVCGKTFIYKHGLKLHQSLHQSQKQFQCELCVKSFVTKRSLQEHMSIHTGESKYLCSVCGKSFHRGSGLSKHFKKHQPKPEVRGYHCTQCEKSFFEARDLRQHMNKHLGVKPFQCQFCDKCYSWKKDWYSHVKSHSVTEPYRCNICGKEFYEKALFRRHVKKATHGKKGRAKQNLERVCEKCGRKFTQLREYRRHMNNHEGVKPFECLTCGVAWADARSLKRHVRTHTGERPYVCPVCSEAYIDARTLRKHMTKFHRDYVPCKIMLEKDTLQFHNQGTQVAHAVSILTAGMQEQESSGPQELETVVVTGETMEALEAVAATEEYPSVSTLSDQSIMQVVNYVLAQQQGQKLSEVAEAIQTVKVEVAHISGGE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***********************************************************************:.********************* ************************************.***********:*****************.*:****.:***********************************************************************************************************************:******************************************* .:** ::** . .*.*** *. :**.**********:**:***** :** **.*.***:::*.. *.:. .** :..* .:.**. *:: **:. *:.: **:*:*** .:* ***. *** *.** ::* ..* *. .** **::.* :* *** * *****************.*****************:.***************************.:**:.********** ****:***.**********************************:**:********.**** ***********************************************************************************************:**:**************:**********************************************************************************************************::*************************************************************************************************** ********.***********************.********* *************************************:*****:. .*", "identical_positions": 926, "similar_positions": 86, "identity": "87.94%" }, { "cls_id": "homologset.agr.RGD:1308276", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5RJQ8-1", "uniprot_id": "CAHM2_RAT", "id": "Q5RJQ8-1", "name": "Calcium homeostasis modulator protein 2", "aln": "MAALIAENFRFLSLFFKSKDVMIFNGLVALGTVGSQELFSVVAFHCPCSPARNYLYGLTAIGVPALALFLIGVILNNHTWNLVAECQYRRAKNCSAAPTFLLLSSILGRAAVAPVTWSVISLLRGEAYVCALSEFVDPSSLTAGDEGFPPDHATEILARFPCGEGPANLSGFREEVSRRLKYESQLFGWLLIGVVAILVFLTKCFKHYCSPLSYRQEAYWAQYRTNEDQLFQRTAEVHSRVLAANNVRRFFGFVALNKDDEELVTKFPVEGTQPRPQWNAITGVYLYRENQGLPLYSRLHKWAQGLTGNGTAPDNVEMALLTV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VEC4-1", "uniprot_id": "CAHM2_MOUSE", "id": "Q8VEC4-1", "name": "Calcium homeostasis modulator protein 2", "aln": "MAALIAENFRFLSLFFKSKDVMIFNGLVALGTVGSQELFSVVAFHCPCSPARNYLYGLTAIGVPALALFLIGVILNNHTWNLVAECQYRRAKNCSAAPNFLLLSSILGRAAVAPVTWSVISLLRGEAYVCALSEFVDPSSLTAGDKGFPPAHATEVLARFPCGEGPANLSSFREEVSRRLKYESQLFGWLLIGVVAILVFLTKCLKHYCSPLSYRQEAYWAQYRTNEDQLFQRTAEVHSRVLAANNVRRFFGFVALNKDDEELVAKFPVEGTQPRPQWNAITGVYLYRENQGLPLYSRLHKWAQGLTGNGTAPDNVEMALLTA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HA72-1", "uniprot_id": "CAHM2_HUMAN", "id": "Q9HA72-1", "name": "Calcium homeostasis modulator protein 2", "aln": "MAALIAENFRFLSLFFKSKDVMIFNGLVALGTVGSQELFSVVAFHCPCSPARNYLYGLAAIGVPALVLFIIGIILNNHTWNLVAECQHRRTKNCSAAPTFLLLSSILGRAAVAPVTWSVISLLRGEAYVCALSEFVDPSSLTAREEHFPSAHATEILARFPCKENPDNLSDFREEVSRRLRYESQLFGWLLIGVVAILVFLTKCLKHYCSPLSYRQEAYWAQYRANEDQLFQRTAEVHSRVLAANNVRRFFGFVALNKDDEELIANFPVEGTQPRPQWNAITGVYLYRENQGLPLYSRLHKWAQGLAGNGAAPDNVEMALLPS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**********************************************************:*******.**:**:**************:**:*******.******************************************** :: **. ****:****** *.* ***.*********:***********************:*******************:**************************************:::****************************************:***:**********. ", "identical_positions": 295, "similar_positions": 22, "identity": "91.33%" }, { "cls_id": "homologset.agr.RGD:1308277", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Y112-1", "uniprot_id": "Q9Y112_DROME", "id": "Q9Y112-1", "name": "NADP-dependent oxidoreductase domain-containing protein", "aln": "----------------MSSKIP-YVKHNNG-----------------------------------TQIQSIGLGTYTSLG---------GDCERATLHAIDVGYRHIDTAYFYENENEVGAAVQRKIAEGVIKREDIHITTKLWCHFHEPKRVEYACRKTLQNFGLQYVDLYLMHWPYSYVYR----GDNEMMPTD-AKGEVEL--NDIDYLDTWREMEKLVELG---LTKSIGVSNFNSEQLTRLLANCKIK--PIHNQIECHPALNQKK--LIALCKKNDIVVTAYCPLGRPNPAEKTPN---------YIYDAKVQAIGDKYKKSTAQVVLRYLIEIGTIPLPKSSNPKRIEENFQ-IFDFQLDAEDHAILDSYNTGERLIPMT---HAIKSKNYPFN-IEF----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VZK8-1", "uniprot_id": "Q9VZK8_DROME", "id": "Q9VZK8-1", "name": "NADP-dependent oxidoreductase domain-containing protein", "aln": "----------------MTGKVEYYFKHNDG-----------------------------------THIQGIGLGTFASTE---------GDCERAVLHAIDVGYRHIDTAYFYGNEAEVGAAVRKKIAEGVIKREDIFITTKLWCNFHEPERVEYACRKTLKNIGLDYVDLYLIHWPFSYKYR----GDNELIPKD-ANGEVEL--VDIDYLDTWGAMEKLVDLG---LTKSIGVSNFNEEQLTRLLANCKIK--PIHNQIEVHPALDQKK--LIALCKKNGILVTAFSPLGRHNAELRTPT---------FMYDGKVQAIADKYNKSIAQVVIRYVIELGTIPLPKSSNPKRIEENFN-VFDFKLDAEDHAILDSYHNGERVAHAR---QAIKSKYYPFN-VYSACF-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VTY2-1", "uniprot_id": "Q9VTY2_DROME", "id": "Q9VTY2-1", "name": "NADP-dependent oxidoreductase domain-containing protein", "aln": "------------------MKLAPTVKLNNG-----------------------------------YEMPILGLGTYNSKD---------NEGEAAVKHAIDVGYRHIDTAYFYQNEAEVGKAIRDKIAEGVVKREDIFLVTKLWNIFHDPERVEGICRKQLSNFGLDYIDLYLMHMPVGYKYV----DDNTLLPKN-EDDVLQL--SDVDYLDTYKAMEKLVKLG---LVRSIGVSNFNSEQLARVLANCEIK--PVTNQVECSPALNQKA--LTAFCKKNDVTLTGYTPLGKPKPDIQKPD---------FIYSPEVAVIAKKYGKTTPQIVLRYLVGLGVIPIPKSSNTNRISENFD-IFDFELTAEEMAVLDGYHTGERVVPLNLI-KGLNHKYYPFS-IEF----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "O60218-1", "uniprot_id": "AK1BA_HUMAN", "id": "O60218-1", "name": "Aldo-keto reductase family 1 member B10", "aln": "--------------------MATFVELSTK-----------------------------------AKMPIVGLGTWKSPL---------GKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKS-----GDD-LFPKD-DKGNAIG--GKATFLDAWEAMEELVDEG---LVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEK--LIQYCHSKGITVTAYSPLGSPDRPWAKPED------PSLLEDPKIKEIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQ-VFDFKLSDEEMATILSFNRNWRACNVL---QSSHLEDYPFN-AEY----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "C9JRZ8-1", "uniprot_id": "AK1BF_HUMAN", "id": "C9JRZ8-1", "name": "Aldo-keto reductase family 1 member B15", "aln": "--------------------MATFVELSTK-----------------------------------AKMPIVGLGTWRSLL---------GKVKEAVKVAIDAEYRHIDCAYFYENQHEVGEAIQEKIQEKAVMREDLFIVSKVWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKT-----GDD-FFPKD-DKGNMIS--GKGTFLDAWEAMEELVDEG---LVKALGVSNFNHFQIERLLNKPGLKYKPVTNQVECHPYLTQEK--LIQYCHSKGITVTAYSPLGSPDRPWAKPED------PSLLEDPKIKEIAAKHKKTTAQVLIRFHIQRNVTVIPKSMTPAHIVENIQ-VFDFKLSDEEMATILSFNRNWRAFDFK---EFSHLEDFPFD-AEY----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "G5E895-1", "uniprot_id": "G5E895_MOUSE", "id": "G5E895-1", "name": "aldose reductase", "aln": "--------------------MAAFVTLLTG-----------------------------------AKMPIVGLGTWKSPP---------AKVREAVKVAIDAGYRHIDCAYVYQNESEVGEAIQEKIQEKAVKREDLFIVSKLWSTFFEKSLVKKAFQNTLSDLKLDYLDLYLIHWPQGFQS-----GNV-FLPTD-DKGSILS--SKYTFLDAWEAMEELVDQG---LVKALGVSNFNHFQIERLLNKPGLKHKPVTNQVECHPYLTQEK--LIQYCHSKGITITAYSPLGSPDRPSAKPED------PLLLEIPKIKEIAAKHKRTAAQVLIRFHIERNVVVIPKSVTPSRIQENIQ-VFDFQLSEEDMAAILSFNRNWRACGLF---AASHNEDFPFH-AEY----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5RJP0-1", "uniprot_id": "ALD1_RAT", "id": "Q5RJP0-1", "name": "Aldo-keto reductase family 1 member B7", "aln": "--------------------MTTFVKLRTK-----------------------------------AKMPLVGLGTWKSPP---------GQVKEAVKAAIDAGYRHFDCAYVYQNESEVGEAIQEKIKEKAVRREDLFIVSKLWSTFFEKSLMKEAFQKTLSDLKLDYLDLYLIHWPQGLQA-----GKE-FLPKD-SQGKVLM--SKSTFLDAWEGMEELVDQG---LVKALGVSNFNHFQIERLLNKPGLKHKPVTNQVECHPYLTQEK--LIQYCHSKGIAVIAYSPLGSPDRPYAKPED------PVVLEIPKIKEIAAKHKKTIAQVLIRFHVQRNVAVIPKSVTLSHIKENIQ-VFDFQLSEEDMAAILSLNRNWRACGLF---VTSDEEDFPFH-EEY----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "M9PF61-1", "uniprot_id": "ALDR_DROME", "id": "M9PF61-1", "name": "Aldo-keto reductase 1B", "aln": "--------------------MNTLMKIQLVRPVFRITLRNYGKPERFMWCQKEYARAPKVVCLDGNEIPVIGLGTFNSPK---------GQVTEAVKVAIDAGYRHIDCAYVYQNEDEVGDGVEAKIKEGVVKREDLFITSKLWNTFHRPDLVKSALENTLSSLKLKYLDLYLIHWPMGYKE-----GCD-LFPTD-KDGKTLY--SPVDYVDTWKAMEKLVEEG---LVKSIGVSNFNRRQIERVLEVATIP--PVTNQIECHPYLTQKK--LIDFCKSKDITITAYSPLGSPNRPWAKAGD------PVILEEAKIKEIAAKKKKTPGQILIRYQVQRANIVIPKSVTKDRIESNFQ-VFDFELTPEEIEIIESFECNGRLVPLL---NQYGHPHHPFEKDEY----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VTL0-1", "uniprot_id": "Q9VTL0_DROME", "id": "Q9VTL0-1", "name": "NADP-dependent oxidoreductase domain-containing protein", "aln": "--------------------MSTPNFLLSN----------------------------------GKNMPMLGLGTWRSPP---------EVVTQAVKDAIDIGYRHFDCAHIYGNEAQVGAALREKMDEGVVTRDELFITSKLWNTHHKPDLVRPACETSIRNLGVKYLNLYLMHWPMAYKS-----GSDNLYPTCPDTNKAAF--EDIDYVDTWRAMENLVDEG---LCQAIGVSNFNEQQMNRLLSVAKLK--PVVLQIECHPYLSQKP--LITLCYDNAIAVTAYSCLGSGHTPYEKPGA------YPLLQHPTILAIAEKYERTAAQVLLRFQTQSGIIVIPRSVSKQHMLDNFKRIWDFELAVDDIQAINELDCNGRFMTMK---AAYGHPHHPFEPKAKVDN-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VHX4-1", "uniprot_id": "Q9VHX4_DROME", "id": "Q9VHX4-1", "name": "NADP-dependent oxidoreductase domain-containing protein", "aln": "------------------MVNTKFLTFNNG-----------------------------------EKMPVIGIGTWQASD---------EEIETAIDAALEAGYRHIDTAPVYGNEKAIGRVLKRWLDAGKVKREELFIVTKVPPVSNRPHEVEPTIKKSLEDLQLDYVDLYLVHTPFTININ----EDGSFKLDK-EGLMEVD--VTTNHAAIWVAMEALVEKG---LTKSIGVSNFSKDQVARLLKNCKIR--PANNQIEHHVYLQQRD--LVDFCKSENITVTAYSPLGSKGIAKFNAGAGIVRDLPDLMDIPEVKEIAASHGKTPAQVLLRWIIDTGVSAIPKSTNPARLKQNLD-VFDFELTAEEVAKLSSLDQNIRICDFAFFHGVERHPEFTFK-NQYTN--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12458-1", "uniprot_id": "YPR1_YEAST", "id": "Q12458-1", "name": "Aldehyde reductase YPR1", "aln": "-------------MPATLKNSSATLKLNTG-----------------------------------ASIPVLGFGTWRSVD---------NNGYHSVIAALKAGYRHIDAAAIYLNEEEVGRAIKD----SGVPREEIFITTKLWGTEQRDP--EAALNKSLKRLGLDYVDLYLMHWPVPLKTDR-VTDGNVLCIPTLEDGTVDIDTKEWNFIKTWELMQELPKTG---KTKAVGVSNFSINNIKELLESPNNKVVPATNQIEIHPLLPQDE--LIAFCKEKGIVVEAYSPFGSANAP--------------LLKEQAIIDMAKKHGVEPAQLIISWSIQRGYVVLAKSVNPERIVSNFK---IFTLPEDDFKTISNLS---KVHGTK---RVVDMKWGSFPIFQ-----", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P14065-1", "uniprot_id": "GCY1_YEAST", "id": "P14065-1", "name": "Glycerol 2-dehydrogenase (NADP(+))", "aln": "-------------MPATLHDSTKILSLNTG-----------------------------------AQIPQIGLGTWQSKE---------NDAYKAVLTALKDGYRHIDTAAIYRNEDQVGQAIKD----SGVPREEIFVTTKLWCTQHHEP--EVALDQSLKRLGLDYVDLYLMHWPARLDPAY-IKNEDILSVPTKKDGSRAVDITNWNFIKTWELMQELPKTG---KTKAVGVSNFSINNLKDLLASQGNKLTPAANQVEIHPLLPQDE--LINFCKSKGIVVEAYSPLGSTDAP--------------LLKEPVILEIAKKNNVQPGHVVISWHVQRGYVVLPKSVNPDRIKTNRK---IFTLSTEDFEAINNIS---KEKGEK---RVVHPNWSPFEVFK-----", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P38115-1", "uniprot_id": "ARA1_YEAST", "id": "P38115-1", "name": "D-arabinose dehydrogenase [NAD(P)+] heavy chain", "aln": "MSSSVASTENIVENMLHPKTTEIYFSLNNG-----------------------------------VRIPALGLGTANPHEK-------LAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKELLEDGSIKREDLFITTKVWPVL--WDEVDRSLNESLKALGLEYVDLLLQHWPLCFEKIKDPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLERLIKECRVK--PTVNQVETHPHLPQME--LRKFCFMHDILLTAYSPLGSHGAPN--------------LKIPLVKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIE---FASLTKDELQELNDFGEKYPVRFIDEPFAAILPEFTGNGPNLDNLKY", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q07551-1", "uniprot_id": "KAR_YEAST", "id": "Q07551-1", "name": "NADPH-dependent alpha-keto amide reductase", "aln": "-----------------MSFHQQFFTLNNGN--------------------------------KIPAIAIIGTGTRWYKNEETDATFSNSLVEQIVYALKLPGIIHIDAAEIYRTYPEVGKALSLTEK----PRNAIFLTDKYSPQIKMSDSPADGLDLALKKMGTDYVDLYLLHSPFVSKEVN-----------------------GLSLEEAWKDMEQLYKSG---KAKNIGVSNFAVEDLQRILKVAEVK--PQVNQIEFSPFLQNQTPGIYKFCQEHDILVEAYSPLGPLQKKTAQDDS--------QPFFEYVKELSEKYIKSEAQIILRWVTKRGVLPVTTSSKPQRISDAQN-LFSFDLTAEEVDKITELGLEHEPLRLYWN-KLYGKYNYAAQKV------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :* ** *:* * * . :* : *: :.:. * : : .*::: * * * : :: : : :***** : :: * *:* * : : * . : : .: :* : :. . .::: : :. * . :: . * :: : ", "identical_positions": 27, "similar_positions": 53, "identity": "6.6%" }, { "cls_id": "homologset.agr.RGD:1308278", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P32921-1", "uniprot_id": "SYWC_MOUSE", "id": "P32921-1", "name": "Tryptophan--tRNA ligase, cytoplasmic", "aln": "MADMPSGESCTSPLELFNSIATQGELVRSLKAGNAPKDEIDSAVKMLLSLKMSYKAAMGEEYKAGCPPGNPTAGRNCDSDATKASEDFVDPWTVR-----TSSAKGIDYDKLIVQFGSSKIDKELINRIERATGQRPHRFLRRGIFFSHRDMNQILDAYENKKPFYLYTGRGPSSEAMHLGHLVPFIFTKWLQDVFNVPLVIQMSDDEKYLWKD-LTLEQAYSYTVENAKDIIACGFDINKTFIFSDLEYMGQSPGFYRNVVKIQKHVTFNQVKGIFGFTDSDCIGKISFPAVQAAPSFSNSFPKIFRDRTDIQCLIPCAIDQDPYFRMTRDVAPRIGHPKPALLHSTFFPALQGAQTKMSASDPNSSIFLTDTAKQIKSKVNKHAFSGGRDTVEEHRQFGGNCEVDVSFMYLTFFLEDDDRLEQIRKDYTSGAMLTGELKKTLIDVLQPLIAEHQARRKAVTEETVKEFMTPRQLSFHFQCFCFDT---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6P7B0-1", "uniprot_id": "SYWC_RAT", "id": "Q6P7B0-1", "name": "Tryptophan--tRNA ligase, cytoplasmic", "aln": "MADMPSGESCTSPLELFNSIAAQGELVRSLKAGNAPKDEIESAVKMLLSLKMNYKTAMGEEYKAGCPPGNSTAGSNGDPDATKASEDFVDPWTVR-----TSSAKGIDYDKLIVQFGSSKIDKELINRIERATGQRPHRFLRRGIFFSHRDMNQILDAYENKKPFYLYTGRGPSSEAMHLGHLVPFIFTKWLQDVFDVPLVIQMSDDEKYLWKD-LTLEQAYSYTVENAKDIIACGFDVNKTFIFSDLEYMGQSPGFYKNVVKIQKHVTFNQVKGIFGFTDSDCIGKISFPAVQAAPSFSNSFPKIFRDRTDIQCLIPCAIDQDPYFRMTRDVAPRIGHPKPALLHSTFFPALQGAQTKMSASDPNSSIFLTDTAKQIKSKVNKHAFSGGRDTVEEHRQFGGNCEVDVSFMYLTFFLEDDDSLEQIRKDYTSGAMLTGELKKTLIDVLQPLIAEHQARRKAVTEETVKEFMAPRQLSFHFQCFCFDT---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P23381-1", "uniprot_id": "SYWC_HUMAN", "id": "P23381-1", "name": "Tryptophan--tRNA ligase, cytoplasmic", "aln": "---MPNSEP-ASLLELFNSIATQGELVRSLKAGNASKDEIDSAVKMLVSLKMSYKAAAGEDYKADCPPGNPAPTSNHGPDATEAEEDFVDPWTVQ-----TSSAKGIDYDKLIVRFGSSKIDKELINRIERATGQRPHHFLRRGIFFSHRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPLVIQMTDDEKYLWKD-LTLDQAYSYAVENAKDIIACGFDINKTFIFSDLDYMGMSSGFYKNVVKIQKHVTFNQVKGIFGFTDSDCIGKISFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAIDQDPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIFLTDTAKQIKTKVNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDYTSGAMLTGELKKALIEVLQPLIAEHQARRKEVTDEIVKEFMTPRKLSFDFQ---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PBS3-1", "uniprot_id": "SYWC_DANRE", "id": "Q6PBS3-1", "name": "Tryptophan--tRNA ligase, cytoplasmic", "aln": "---------MSSPLDLYECVTAQGETVRSIKAKKGSKEEVDAAVQVLLQMKLDYKRVTGQDYKAGCPPQDGVTPQDG--AAPQDGEDQVDPWSVS-----SSSAKGVDYEKLIVRFGSSKVDQELVDRISRLTGKTPHRFLRRGIFFSHRDMHQILDAFEQQKPFYLYTGRGPSSQAIHVGHLIPFIFTKWLQDVFDVPLVIQLTDDEKYLWKD-LTLEECRRFTVENARDIIACGFDVNKTFIFSDLEYMGASPAFYRNVVKVQKHVTFNQVKGIFGFTDSDCIGKISFPAIQAAPSFSNSFPQIFGDRKDVQCLIPCAIDQDPYFRMTRDVAPRIGYLKPALLHSTFFPALQGAQTKMSASDANSTIFLTDTPKQIKNKVNKHAFSGGKDTIEEHRKLGGDPDVDVSFMYLTFFLEDDEQLEKIRQDYSSGAMLTGELKKSLIDTLQPIIAEHQEKRKHVTDDIVQQFMTPRKLHFSC----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q0KI98-1", "uniprot_id": "Q0KI98_DROME", "id": "Q0KI98-1", "name": "Tryptophan--tRNA ligase, cytoplasmic", "aln": "-----------------------------------MADTKETVVEGVEALTLNGK--------PDAEPVETGTDAQAQEGATAPTEDVVDPWNVA-----SSNDAGVDYDKLIKRFGSSKIDEELIARFEKITGKPAHHFIRRGMFFSHRDLHTILTLREQGKPFYLYTGRGPSSGSLHVGHLVPFIMTKWLQETFDVPLVIQLTDDEKTLWKD-LKVEDAIKLGRENAKDIVAIGFDVNKTFIFNNLEFVGKCPAMYQNIIRIQKCVTFNQVKGIFGFGDSDIIGKIGFPAAQAAPAISSTFPFIFGNRK-VHCLIPCAIDQDPYFRMTRDVAPRLGFPKCALIHSTFFPALQGAKTKMSASDQNSAVYLTDTPKQIKNKINKYAFSGGRVSVEEHRKLGGVPEVDVSYQLLKFFLEDDAKLEEVRVAYSKGEMLTGEIKKLAVETLTPIVEQHQAARKLITDEVLDKYFELRPLKFGS----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12109-1", "uniprot_id": "SYWC_YEAST", "id": "Q12109-1", "name": "Tryptophan--tRNA ligase, cytoplasmic", "aln": "---------------------------------MSNDETVEKVTQQVSELK-----------------------------STDVKEQVVTPWDVEGGVDEQGRAQNIDYDKLIKQFGTKPVNEETLKRFKQVTGREPHHFLRKGLFFSERDFTKILDLYEQGKPFFLYTGRGPSSDSMHLGHMIPFVFTKWLQEVFDVPLVIELTDDEKFLFKHKLTINDVKNFARENAKDIIAVGFDPKNTFIFSDLQYMGG--AFYETVVRVSRQITGSTAKAVFGFNDSDCIGKFHFASIQIATAFPSSFPNVLGLPDKTPCLIPCAIDQDPYFRVCRDVADKLKYSKPALLHSRFFPALQGSTTKMSASDDTTAIFMTDTPKQIQKKINKYAFSGGQVSADLHRELGGNPDVDVAYQYLSFFKDDDVFLKECYDKYKSGELLSGEMKKLCIETLQEFVKAFQERRAQVDEETLDKFMVPHKLVWGEKERLVAPKPKTKQEKK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : ..: : :. :. *: * ** * . .:**:*** :**:. :::* : *:.: **: .*:*:*:*:***.**: :* *: ***:********* ::*:**::**::*****:.*:*****:::**** *:*. *.::: ***:**:* *** ::****.:*:::* .:*..::::.: :* . .*.:*** *** ***: *.: * *.::..:** :: **************: **** :: . * **:** *******: ******* .:::::***.***:.*:**:*****: : : **::** :***:: *.** :** *:: *..* :*:**:** ::.* :: .* * : :: :.::: : * : ", "identical_positions": 169, "similar_positions": 140, "identity": "34.07%" }, { "cls_id": "homologset.agr.RGD:1308279", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LN30-1", "uniprot_id": "A0ABK0LN30_RAT", "id": "A0ABK0LN30-1", "name": "", "aln": "MQIRQRHFLRQLSAIFSFWRAGGGTGAGRGSRRVGGGRGGVATAAGRGAPRAPWIFVKVLCFAPLMVPEAPRQPFLGTAQGASLGSTHPTGPREFIHLKRKISKMFQIPVQNLDNIRKVRKRVKGILVDIGLDSCKELLKDLKGFDPGEKYFCNTSWGDVSLWEPSGKR--AKYRTKPYCCSLCRYSTKVLTSLKNHLHRYHEEEADQELMIPCPNCPFASQPKVVGKHFRMFHAPARKVQS--------YTVNILGEAKTSRSDVISFTCLKCNFSNTLYYSMKKHVLVAHFNYLINSYFGLRTEETGEQPKASDPVSVDKALPFDKYYCKKCSAIASSQDALMYHILTSDAHRDLENKLRSVISEHIKR---TGFLKQMHIAPKPVTHIALPPNSSAPSIAAPPPCFQLALPQNSQSPGTVQSVTVAPGTSGSLTHSPPTTAQSHVALVSSSLPVCQSSLTLQQSAPPPVFLSHSVPLSQPVSTSVLPLTQPLGPVNKSVGTSLLPVNQAMCSVNQAVRPGVLPLPKPMGPINRPVGPGVLPVGPSVNSGVLQATSPGVISVGRAVPSGVLPAGQVT------PAGVIPGQTATSGVLPTGQVVQSSVLPVGQTAPSRVLPPGQTVPLRVLPAGQVVPPGLLSPNQTVP-SGVVPVNQGVNSGVLQLSQPVTPGVLPVGPPVRPGVLQLSPSVSTSILPVSQPVRAGTSQNTTFLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPSAGGLAAVGPPPQVPVQFLPSSSGTQMGSSLPSLPSPQVLVSPAPSVFVQATPPVADANQALRQAKQWKTCPVCNELFP----------------------------ANVYQVHMEVAHTQSEAKSSEKPEPERLAACAPFLKWMREKTVRCLSCKCLVSQEELMHHLLMHGLGCLFCPCTFHDVRGLVEHSRTKHLGKKRLSMDYSNRGFQLDLDANGNLLFPHLDFITILPREKLGEREVYLAILAGIHSKSLVPVYVKVRPQPEVAPKIPNRQKLTCPFCFGTFMAADAYELHLKERHHVMPTVHTMLRSPAFKCIHCCGVYTGNMTLGAIAVHLLRCRSAPKDS-SSDLQAQPDFIESSELLMVNGEVIPESTFPLKRKLPEGHLGPEEQGDGDEPQLTVDTDASPGSEKGLSAVPLKRQKNESRTEGSGASDDSLQVLALDPSKYGSRSYEEKKQFLRDYFHKRPYPSRKEVELLSSLLWVWKIDVASFFGKRRYICMKAIKSHKPSVLLGFDMSELKNVKHRLNF-ECESENL---------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CHC8-1", "uniprot_id": "ADNP2_MOUSE", "id": "Q8CHC8-1", "name": "Activity-dependent neuroprotector homeobox protein 2", "aln": "--------------------------------------------------------------------------------------------------------MFQIPVQNLDNIRKVRKRVKGILVDIGLDSCKELMKDLKSFDPGEKYFYNTSWGDVSPWEPSGKK--ARYRTKPYCCSLCRYSTKVLTSLKNHLHRYHEDEADQELMIPCPNCPFSSQPRVVGKHFRMFHAPARKVQS--------YTVNILGETKTSRSDVISFTCLKCNFSNTLYYSMKKHVLVAHFNYLINSYFGLRTEETGEQPKASDPVSVDKILPFDKYYCKKCSAIASSQDALMYHILTSDAHRDLENKLRSVISEHIKR---TGFLKQMHIAPKPVTHLALPPNSSAPSIAAPPPCFQLALPQNSQSSGTVQSVTVTPGTSGSLTHSPPTTAQSHVALVSSSLPVCQSSLSLQQSAPPPVFLSHSVALNQPVNTAVLPLTQPVGPVNKSVGTSILPVNQAMCSVNQAVRPGLLPLTKPMGPMNRPVGPAVLPMGPSVNSGVLQATSPGVISVGRAVPSGVLPAGQVT------PAGVIPGQTATSGVLPTGQVVQSSTLPVGQTAPSRGLPPGQTVPLRVLPAGQVVPSGLLSSNQTVP-SGVVPVNQGVNSGVLQLGQPVTPGVLPVGPPVRPGVLQLSPSVSTSILPMSQPVRAGTSQNTTFFTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPSGGGLAAVGPPPQVPVQFLPSGSGTQMGSSLPSLPSPQVLVSPAPSVFVQATPPLADANQALKQAKQWKTCPVCNELFPSNVYQVHMEVAHKQSEAQLCQVCNELFPANVYQVHMEVAHKQSESKSSEKLEPEKLAACAPFLKWMREKTVRCLSCKCLVSQEELMHHLLMHGLGCLFCPCTFHDVRGLVEHSRTKHLGKKRLSMDYSNRGFQLDLDANGNLLFPHLDFITILPREKLGEREVYLAILAGIHSKSLVPVYVKVRPQPEVAPKIPNKQKLTCPFCLSTFMTADAYELHLKERHHVMPTVHTMLRSPAFKCIHCCGVYTGNMTLGAIAVHLLRCRSAPKDS-SSDLQVQPGFIESSELLMVNGDVIPESTFPVKRKLPEGHLGPEDQRDGEEPQLTLDADASSGSEKGLGAVPLKRQKSEIRTEGSGPSEDSLQALALDPSKYEGRSYEEKKQFLRDYFHRRPYPSRKEVELLSSLLWVWKIDVASFFGKRRYICMKAIKTHKPSVLLGFDMSELKNVKHRLNFGECESQKL---------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6IQ32-1", "uniprot_id": "ADNP2_HUMAN", "id": "Q6IQ32-1", "name": "Activity-dependent neuroprotector homeobox protein 2", "aln": "--------------------------------------------------------------------------------------------------------MFQIPVENLDNIRKVRKKVKGILVDIGLDSCKELLKDLKGFDPGEKYFHNTSWGDVSLWEPSGKK--VRYRTKPYCCGLCKYSTKVLTSFKNHLHRYHEDEIDQELVIPCPNCVFASQPKVVGRHFRMFHAPVRKVQN--------YTVNILGETKSSRSDVISFTCLKCNFSNTLYYSMKKHVLVAHFHYLINSYFGLRTEEMGEQPKTNDTVSIEKIPPPDKYYCKKCNANASSQDALMYHILTSDIHRDLENKLRSVISEHIKR---TGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQPVTVAQGAPGSLTHSPPAAGQSHMTLVSSPLPVGQNSLTLQPPAPQPVFLSHGVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPIN-------QTVRPGVLPLTQPVGPINRPVGPGVLPVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQMTPAGVIPGQTATSGVLPTGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISAGQVVPSGLLSPNQTVSSSAVVPVNQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQTVGTNILPVNQPVRPGASQNTTFLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPP-GGLATVAPP-QMPIQLLPSGAAAPMAGSMPGMPSPPVLVNAAQSVFVQASSSAADTNQVLKQAKQWKTCPVCNELFP----------------------------SNVYQVHMEVAHKHSESKSGEKLEPEKLAACAPFLKWMREKTVRCLSCKCLVSEEELIHHLLMHGLGCLFCPCTFHDIKGLSEHSRNRHLGKKKLPMDYSNRGFQLDVDANGNLLFPHLDFITILPKEKLGEREVYLAILAGIHSKSLVPVYVKVRPQAEGTPGSTGKRVSTCPFCFGPFVTTEAYELHLKERHHIMPTVHTVLKSPAFKCIHCCGVYTGNMTLAAIAVHLVRCRSAPKDS-SSDLQAQPGFIHNSELLLVSGEVMHDSSFSVKRKLPDGHLGAEDQRHGEEQPPILNADAAPGPEKVTSVVPFKRQRNESRTEGPIVKDEALQILALDPKKYEGRSYEEKKQFLKDYFHKKPYPSKKEIELLSSLFWVWKIDVASFFGKRRYICMKAIKNHKPSVLLGFDMSELKNVKHRLNF-EYEP------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A4QP16-1", "uniprot_id": "ADN2A_DANRE", "id": "A4QP16-1", "name": "Activity-dependent neuroprotective protein 2a", "aln": "--------------------------------------------------------------------------------------------------------MYQIPVKNLTKLRRPRKRVKSILCDIGMQQCQDMLETYKCFDAGDASFDNTEWDDFTDGHVGKKKKKYPYRSQSLCCSLCWYSSRSVPTFRSHIHRCHWKNLDGACLLMCPYCPFVSSPKVTEQHIQFFHMLPSRAHQSHPSHTLAHTPKTISVTVSADAADDRYTCATCGYHDSLLYVMKKHVLVNHFATLLDRYFGLGSESAPMAG------PQIRDGTPVKYHCKLCKLPAETIEHLLYHILSSEKHKELHWQIMPCIIEKECMNQMVGLQNLLNLAPKSMQPVTLFARPN-------------YMPQQTQQTNGNGTVLLAGPSNAAALFCSPGAGQMFLSPQTQALLSGTTVAALQNAPHP-------------------------------------------------QSPGGMSQVLPTSPVVKPLN----------------------------------------------------------MVMPNMPQNTPKTLPLTMTVPR--LPPPQQGPQVLLPPGVQVN---------------LPGEMGVHSPFLVTQG-----------------LQLNQSVPRAPLITSQSVR------------------FIPTGNKVNGVPTYTLAPVQVTVPVHG--------GPPQMVLAQNQISQPPNSAVVTPGLMPP------------------------------------------------------------------------------------VQRAMNKNSRPNELAVQAPFLKKHDNQTVKCLRCKILLTEQGIFQHLLHG-LKCLFCPQMFYSFKQIMEHSKKEHSLKVKDNRLYIKEQFSLDCDDEGNLIFSTFNLNTDVPKDLLDNRELNLALVTSTKDK----IYIKMYPDKAEYTTMLKSAPNACPFCQVKLQNPEDYELHLQTKHHIVPTIHAILKTPAYKCIYCFGVYTEKSTPKTISIHVQRCRCAPKAVKEAERKLNPDTSESHDGDVCSSVQMPAS------------------------EVTFQGAPEFPKPKKEAVTPRNRRRNTKASKTGTLVPETPVTLVLEPMGMERTSFEDRKDFLSQYFHRKPYVTKTEIELLASRLWINKADVKAHFNSKLTKCLKAIQKKRVCVRLGFKMIEVNKLKHNLFIPEVKPVKRKDPNEVNLSSLVPGVTVKTEQVDATTQHPLFIPEVPVTIKKEEEVCEIDHGFIIQEVTVKQEEVDEMEDALCTNG", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:****:** ::*: **:**.** ***::.*::::: * **.*: * **.*.*.: . . *: **::. **.** **:: :.:::.*:** * .: * :: ** * * *.*:*. :*:::** :.:. :* : :. : :: : :** .*.: ::* * ******* ** *:: **** :*. . : . **:** *. *.: : *:****:*: *::*. :: . * *: .*: : ::***. :: .. . :**:: .. .* :: : .: ...* :.* .:: :..* . :** .. ** :. * .*: :*:. *:*. . .**: *.* *** * * ::..* * :* : **:* .* ***. :* * .*.** :****::***:********.**:** * *: : . . . *.: .* : .:: .*:.**. ***** ::**:** ** *:::: :::*** * ***** *:..: : ***:..* * : * :. *.** * :***:*. ::: * :*:: *.:**: **:::. :.* :*:*: *: . :**** : .: *****: :**::**:*::*::**:***:* **** : * :*::*: ***.*** .:: : :*. .. : : .. : * .: . * ...* :*::. :: :: *.*:* *:*::*:** :***::** ::.*:***:* :*: * ** :.*..: *:***:.:: .* ***.* *::::**.* : * :. ", "identical_positions": 280, "similar_positions": 301, "identity": "20.51%" }, { "cls_id": "homologset.agr.RGD:1308280", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VS87-1", "uniprot_id": "Q9VS87_DROME", "id": "Q9VS87-1", "name": "Peptidase S1 domain-containing protein", "aln": "MTSNLSGIVVIANLWILVVGGQSKNWSGYYVDNGTHYLLYEGPRIKPQTFLPGNISTNPAINALEAQDYLPTRIVNGKKIKCSRAPYQCAL---HYNNYFICGCVILNRRWILTAQHCKIG-NPGRYTVRAGSTQQRRGG---QLRHVQKTVCHPNYSEYTMKN----DLCMMKLKTPLNVGRCVQKVKLPSTRTKRFPKCYLASGWGLTSANAQNVQRYLRGVIVCKVSRAKCQQDYRGTGIKIYKQMICAKRK--NRDTCSGDSGGPLVHNGVLYGITSFGIG-CASAKYPGVYVNVLQYTRWIKKVAKKY-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IQ89-1", "uniprot_id": "Q8IQ89_DROME", "id": "Q8IQ89-1", "name": "Peptidase S1 domain-containing protein", "aln": "MYQNFGSESEGR--------ERDPSWSGYYKDNGTHYLLYGKPEDIAPTPNFGNISSNPFINALEAQESFPTRIVNGKRIPCTEAPFQGSL---HYEGYFVCGCVIINKIWILTAHHCFFG-PPEKYTVRVGSDQQRRGG---QLRHVKKIVALAAYNDYTMRH----DLAMMKLKSPVYFGKCVRPVKLPSTKTTKFPKKFVVSGWGITSANAQNVQRYLRRVQIDYIKRSKCQKMYKKAGLKIYKDMICASRT--NKDSCSGDSGGPLTSRGVLYGIVSWGIG-CANKNYPGVYVNCKRYVPWIKKVIHKY-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VQ98-1", "uniprot_id": "Q9VQ98_DROME", "id": "Q9VQ98-1", "name": "trypsin", "aln": "--------------------------------------------------MFVQWIFLAFSVTVVSSNWIPERIVGGDLITILSVPWQASI---LRLGRFHCGAAIYSEDIVITAAHCLTDRETEFLSVRVGSSFTFFGG---QVVRVSSVLLHEEY-DQSWSN----DIAVMRLQSKLRLGSAVSVIPLADTPPASG-SPATVSGWGAIGFKKNYPMSILS-ASVDIVDQDQCRRSY---GRKITKDMICAAAP--GKDACSGDSGGPLVSGNKLVGIVSFGKE-CAHPEYPGVYANVAELKPWILGAIERITKSE---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9UKQ9-1", "uniprot_id": "KLK9_HUMAN", "id": "Q9UKQ9-1", "name": "Kallikrein-9", "aln": "------------------------------------------------MKLGLLCALLS---LLAGHGWADTRAIGAEECRPNSQPWQAGL---FHLTRLFCGATLISDRWLLTAAHCRK----PYLWVRLGEHHLWKWEGPEQLFRVTDFFPHPGFNKDLSANDHNDDIMLIRLPRQARLSPAVQPLNLSQTCVSPG-MQCLISGWGAVSSPKALFPVTLQCANISILENKLCHWAYPG---HISDSMLCAGLWEGGRGSCQGDSGGPLVCNGTLAGVVSGGAEPCSRPRRPAVYTSVCHYLDWIQEIMEN--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "G3V934-1", "uniprot_id": "G3V934_RAT", "id": "G3V934-1", "name": "", "aln": "------------------------------------------------MKLGLTLVLFS---LLAGHCGADTRAVGARECQRNSQPWQAGL---FYLTRQLCGATLINDQWLLTAAHCRK----PYLWVRLGEHHLWQWEGPEKLLLVTDFFPHPGFNPDLSANDHNDDIMLIRLPRKVRLSPAVQPLNLSQSLPSVG-TQCLISGWGSVSSSKIQFPMTLQCANISILDNKLCRWAYPG---HISEKMLCAGLWEGGRGSCQGDSGGPLVCKGTLAGIVSGGSEPCSRPQRPAVYTSVFHYLDWIENTVEKYNHTNKLI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A1ZA64-1", "uniprot_id": "A1ZA64_DROME", "id": "A1ZA64-1", "name": "trypsin", "aln": "----------------------------------------------MSLRLGLFLLAALGVVILTDSASISTHIVGGDQADIADFPYQVSVRLETYMLLHICGGSIYAPRVVITAAHCIKGRYASYIRIVAGQNSIADLE--EQGVKVSKLIPHAGYNKKTYVN----DIGLIITREPLEYSALVQPIAVALEAPPSG-AQAVVSGWGKRAEDDEALPAMLRAVELQIIEKSTCGAQYLTKDYTVTDEMLCAGYLEGGKDTCNGDSGGPLAVDGVLVGVVSWGVG-CGREGFPGVYTSVNSHIDWIEEQAEAYL------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :.. *:* .: ** : ::** ** : *. : * . . : : *: :: . * : :. **** . * . : :.. * * : ..*:** .:.:*.*******. . * *:.* * *. *.**.. ** . ", "identical_positions": 40, "similar_positions": 49, "identity": "12.5%" }, { "cls_id": "homologset.agr.RGD:1308281", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "B0BNG5-1", "uniprot_id": "B0BNG5_RAT", "id": "B0BNG5-1", "name": "Hypoxia-inducible factor 1-alpha inhibitor", "aln": "MWKFHLYGVRCGCSGKGGAPTSGGAVPRVEMAATAAEVAASASGEAREEAEAPGPAWDESQLRSYSFPTRPIPRLSQSDPRAEELIENEEPVVLTDTNLVYPALKWDLEYLQENIGNGDFSVYSASTHKFLYYDEKKMANFQNFKPRSNREEIKFHEFVEKLQAIQQRGGEERLYLQQTLNDTVGRKIVMDFLGFNWNWINKQQGKRGWGQLTSNLLLIGMEGNVTPAHYDEQQNFFAQIKGHKRCILFPPDQFECLYPYPVHHPCDRQSQVDFDNPDYERFPNFRNVVGYETVVGPGDVLYIPMYWWHHIESLLNGGITITVNFWYKGAPTPKRIEYPLKAHQKVAIMRNIEKMLGEALGNPQEVGPLLNTMIKGRYN----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BLR9-1", "uniprot_id": "HIF1N_MOUSE", "id": "Q8BLR9-1", "name": "Hypoxia-inducible factor 1-alpha inhibitor", "aln": "------------------------------MAATAAEVAASGSGEAREEAEAPGPAWDESQLRSYSFPTRPIPRLSQSDPRAEELIENEEPVVLTDTNLVYPALKWDLEYLQENIGNGDFSVYSASTHKFLYYDEKKMGNFQNFKPRSNREEIKFHEFVEKLQAIQQRGGEERLYLQQTLNDTVGRKIVMDFLGFNWNWINKQQGKRGWGQLTSNLLLIGMEGNVTPAHYDEQQNFFAQIKGHKRCILFPPDQFECLYPYPVHHPCDRQSQVDFDNPDYERFPNFRNVVGYETVVGPGDVLYIPMYWWHHIESLLNGGITITVNFWYKGAPTPKRIEYPLKAHQKVAIMRNIEKMLGEALGNPQEVGPLLNTMIKGRYN----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NWT6-1", "uniprot_id": "HIF1N_HUMAN", "id": "Q9NWT6-1", "name": "Hypoxia-inducible factor 1-alpha inhibitor", "aln": "------------------------------MAATAAEAVASGSGEPREEAGALGPAWDESQLRSYSFPTRPIPRLSQSDPRAEELIENEEPVVLTDTNLVYPALKWDLEYLQENIGNGDFSVYSASTHKFLYYDEKKMANFQNFKPRSNREEMKFHEFVEKLQDIQQRGGEERLYLQQTLNDTVGRKIVMDFLGFNWNWINKQQGKRGWGQLTSNLLLIGMEGNVTPAHYDEQQNFFAQIKGYKRCILFPPDQFECLYPYPVHHPCDRQSQVDFDNPDYERFPNFQNVVGYETVVGPGDVLYIPMYWWHHIESLLNGGITITVNFWYKGAPTPKRIEYPLKAHQKVAIMRNIEKMLGEALGNPQEVGPLLNTMIKGRYN----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P59723-1", "uniprot_id": "HIF1N_DANRE", "id": "P59723-1", "name": "Hypoxia-inducible factor 1-alpha inhibitor", "aln": "------------------------------MAETDGAAAFT---ELRD------PDWDESQLRQYTFPTRQIPRLSHTDPRAEVLINNEEPVVLTDTSLVYPALKWDIPYLQENIGNGDFSVYIAENHKFLYYDEKKMVNFQDFVPKSRRIEMKFSEFVDKMHQTEEQGGKGRVYLQQTLNDTVGRKIVVDFLGFNWNWINKQQAKRNWGPLTSNLLLIGMEGNVTPAHYDEQQNFFAQIKGHKRCILFPPDQFDCLYPYPVHHPCDRQSQVDFENPDYDKFPNFKNAVGYEAVVGPGDVLYIPMYWWHHIESLLNGGETITVNFWYKGAPTPKRIEYPLKAHQKVAIMRNIEKMLGEALGDPHEVGPLLNMMIKGRYDHGLS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** * . .. : * *: * *******.*:**** *****::***** **:**********.*********: ************** *..*********** ***:* *:*.* *:** ***:*:: :::**: *:***************:**************.**.** *******************************:***********:*******************:****::****:*.****:************************* ******************************************:*:******* ******: ", "identical_positions": 280, "similar_positions": 40, "identity": "73.11%" }, { "cls_id": "homologset.agr.RGD:1308282", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P0CE46-1", "uniprot_id": "ZNT8_RAT", "id": "P0CE46-1", "name": "Proton-coupled zinc antiporter SLC30A8", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------MEFLERTYLVNDQATKMYAFTSD-RERGQKP-----VNKD-----QCPGDGPE-------------------------------------------------------------------------------------------------------------------------------------------RPEAGAIY---------------HCHNSFKATGNRSSKQVHAKWRLCAASAICFFFMVAEVVGGHVAGSLAVLTDAAHLLIDLTSFLLSLFSLWLSSRPPSKRLTFGWYRAEILGALLSVLCIWVVTGVLVYLACERLLYPDYQIQAGIMITVSGCAVAANIVLTLILHQRHLG-------HNHK-------------------------------------------------------------------------------DAQANASVRAAFVHALGDVFQSTSVLISALIIYFKPDYKMADPVCTFISSVLALASTVMILKDFSILLMEGVPKGLSYNSVKELLLTVDGVISVHNLHIWSLTVNQVILSVHVATAASQDSQSVRTGIACALSSSFDLHSLTIQIESAADQDPSCLLCEDPQD-----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BGG0-1", "uniprot_id": "ZNT8_MOUSE", "id": "Q8BGG0-1", "name": "Proton-coupled zinc antiporter SLC30A8", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------MEFLERTYLVNDQATKMYAFPLD-RELRQKP-----VNKD-----QCPGDRPE-------------------------------------------------------------------------------------------------------------------------------------------HPEAGGIY---------------HCHNSAKATGNRSSKQAHAKWRLCAASAICFIFMVAEVVGGHVAGSLAILTDAAHLLIDLTSFLLSLFSLWLSSRPPSKRLTFGWYRAEILGALLSVLCIWVVTGVLLYLACERLLYPDYQIQAGIMITVSGCAVAANIVLTMILHQRNFG-------YNHK-------------------------------------------------------------------------------DVQANASVRAAFVHALGDVFQSISVLISALIIYFKPDYKIADPVCTFIFSILVLASTVMILKDFSILLMEGVPKGLSYNSVKEIILAVDGVISVHSLHIWSLTVNQVILSVHVATAASQDSQSVRTGIAQALSS-FDLHSLTIQIESAADQDPSCLLCEDPQD-----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IWU4-1", "uniprot_id": "ZNT8_HUMAN", "id": "Q8IWU4-1", "name": "Proton-coupled zinc antiporter SLC30A8", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------MEFLERTYLVNDKAAKMYAFTLESVELQQKP-----VNKD-----QCPRERPE-------------------------------------------------------------------------------------------------------------------------------------------ELESGGMY---------------HCHSGSKPTEKGANEYAYAKWKLCSASAICFIFMIAEVVGGHIAGSLAVVTDAAHLLIDLTSFLLSLFSLWLSSKPPSKRLTFGWHRAEILGALLSILCIWVVTGVLVYLACERLLYPDYQIQATVMIIVSSCAVAANIVLTVVLHQRCLG-------HNHK-------------------------------------------------------------------------------EVQANASVRAAFVHALGDLFQSISVLISALIIYFKPEYKIADPICTFIFSILVLASTITILKDFSILLMEGVPKSLNYSGVKELILAVDGVLSVHSLHIWSLTMNQVILSAHVATAASRDSQVVRREIAKALSKSFTMHSLTIQMESPVDQDPDCLFCEDPCD-----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TDG6-1", "uniprot_id": "A0AB32TDG6_DANRE", "id": "A0AB32TDG6-1", "name": "Proton-coupled zinc antiporter SLC30A8", "aln": "----------MSVFSEPALEKKLSELSNSQQSVQTLSLWLIHHRKHSKTIVKVWYS-ELKKAQVSRKLTFLYLANDVIQNSKRKGPEFTQDFAPVIVDAFKHVSSGGDESCKKHLGR---------------------------VLSIWQERAVYENDILDKLADVLQVEKKAQKRPYEEIKVNVDDFACQSSPAEPPQTADLIRTLQELENAASSDAALRKRISALPPEVQDTSLLHKVQDKESGERLSRLVEEACMLLADYSGRLAAEIDDRRQLTRTLAVFLQSQRDGLVQNEQKLEEYKRKLARVSQVRKELRSRLNGLPDLSRLPNVTGGHMRLPSSGDLYSPSDCMPSVDMKDGKHCHDNNRALEDREREKKIAKKRLYIVSAVCLVFMVGEILGGYFAGSLAVMTDAAHLLVDLTSFIISLCSLWLSSRPATRTLNYGWHRAEILGALLSIFTIWLVTGVLVYLAVERIINDNFTIEGTVMLITSGCAVLANIIMALTLHQSGHG-------HSHGGLSAGHGHSHDHG---------------------------------------------KENGHSHSDGSHHDVEEQRPGKTQANASVRAAFVHVIGDLLQSISVLVSALIIFFKPEYKIADPICTFLFSLFVLGTTFTIMRDIVIVLMEGTPAGVNYNEVRQLLLGVKGVKAVHNLHIWALTMNQAVLSAHVATDETVDPQEVLREMTQVCFTKYSFHSVTIQLEPQADQRPDCSLCQDPAK-----------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V471-1", "uniprot_id": "Q9V471_DROME", "id": "Q9V471-1", "name": "", "aln": "-----------------------------------------------------------MSRNED-----TPIAKRDSGRTR---------------------------------------------------------------RSNYG-----------TAPSFHLMEQG--------------------QPGVNVVAGN----GNNN----------------------------------------------------HPATPATP-----------------------------------------------------------------AQIFCLHGRSN--------NVEVRD-HCHR-ARSEG----VDVKARRKLIIASILCLVFMIAEIVGGVLSNSLAIATDAAHLLTDFASFMISLFAIWIAGRPSTQRMSFGWYRAEVIGAMASVFMIWVITGILVWLAIGRLISGDYEVNAKIMLITSGLAILVNVIMGVQLQHGHSHGLGGGHGHSHGGSKNASHVQATSTPCSDSPSQRIEGGVAYAPEDAELPGGGLPTFSYQNTKLVDPTLDLEIAAVLAETAPGSHHHGGPVGREAVNMNVRAALIHVIGDVIQSVGVFVAAGVIYFWPEYSIVDPICTFVFSIIVLFTTFTIMKDALLVLMEGTPNYMHYAEVLQIFQGIEGVERVHNLRIWALSINKVALSAHLAIAENANPKRILDAATSAVHLRYNFFETTIQIEDYTAQMESCLQCNVPEK-----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VKA3-1", "uniprot_id": "Q9VKA3_DROME", "id": "Q9VKA3-1", "name": "", "aln": "MSKKSLKRQDEHTKDNDCEEEDEEELQAAIREMVKIPDIDIIPRKSSESVREKESTGNVLKKNHDERGSQTGDGKDTTSKTRQKKLESDDSWAALLRKRFAWTKDNKTDAVNQNIPNTKGSSKDFTENKGSGNKHSTVTSNEKLIRSEYYENSQTKSDAIKSLSNNQLSEESPEFLNKLRRIEEASKPKTWKRPTPVVLKSNQNYSANKNSENALDAKPQTATNTEETHGCINILKVPFQSNLYYVPEKPSRQDKGSGTSDFQPGAPETPIVENSAVDSDRKAVEIMPENVKNSEEKKIDN-------------------------------SDSTKTVTITGHSH--------ITAKWDGHCHFKERETG----VDKAARRVLIIACILCTIFLILEVIGGILSNSLAIATDAAHLLTDLASFLISISALHLAGRPSSERLNYGWHRAEVIGAMVSIFFIWVVTGILVYMAIMRWVNQDFELDAKIMLITSALAILFNVIMAMQLQHGHSHSLPG----VHKMSKDAGSVLGS-----------------------------------------------KMILLLGKSVSMQYAAKG-----HENINVRAAIIHVVGDIIQSFGVFVAALIIFFWPEWAFMDSVCTFVFSVLVLVVTFKILRDVLMVLMEATPDFMDYEEVKQTFLSISGVEHVHNLRIWALSINKVALSAHLAISKDADPQLILEEATTLIHKRFKFFETTIQIEEYSPGMENCGQCLSPSDKSGKRKSSDPEKGEGKAGRKRGSDVGKIKNHSGSE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . * * *** : *: * .. :* .*:: *::** .:.***: ******* *::**::*: :: ::.:*.:. :.:**:***::**: *:: **::**:*:::* * : :: ::. :*: .*. *: *::: : *:: * * .****::*.:**::** .*:::* :*:* *:: : *.:***: *::.* *. *::* ::***..* : * * : : :.** **.*:**:*::*:. **.*:* :.: : : : :.. ***:* .* * * . ", "identical_positions": 98, "similar_positions": 117, "identity": "12.25%" }, { "cls_id": "homologset.agr.RGD:1308283", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q3UQ84-1", "uniprot_id": "SYTM_MOUSE", "id": "Q3UQ84-1", "name": "Threonine--tRNA ligase, mitochondrial", "aln": "--------------------------MGLCLRWRRLGFPLPEFRRCELHTVREAS--------------------APTPPHWLAERFGLFEELWTAHVKKLASMTQKKARAIKISLPEGQKVDAVAWNTTPYQLAHQISVTLADTAVAAEVNGELYDLDRPLETDC----HLRFLTFDSPEGKAVFWHSSAHVLGAAAEQQLGAVLCRGPSTESGFYHDFFLGKER---------TVRSAELPILERICQELIAAAQPFRRLEASRDQLRQLFKDNHFKLHLIEEKVTG-PTATVYGCGMSVDLCRGPHLRHTGQIGALKLLTNSSALWRSLGAPETLQRVSGISFPKVELLRNWEARREAAELRDHRRIGKEQELFFFHELSPGSCFFLPRGTRVYNALVAFIRAEYARRGFSEVKTPTLFSTKLWEQSGHWEHYRADMFSLKPPGTDGVDNSQSGHPARCPKDTLALKPMNCPAHCLMFAHRPRSWRELPVRLADFGALHRAEASGSLGGLTRLWRFQQDDAHIFCAPHQLEAEIQGCLDFLRCVYSVLGFSFHLALSTRPPGFLGEPRLWDQAEQVLQQALEKFGEPWDLNPGDGAFYGPKIDVHLHDALGRPHQCGTIQLDFQLPLRFDLQYKGPAGTPE---CPVLIHRAVLGSVERLLGVLAESCGGKWPLWLSPLQVVVIPVRTEQEEYARQVQQCLQAAGLVSDLDADSGLTLSRRVRRAQLAHYNFQFVVGQREQSQRTVNVRTRDNR----QLGERDLAESVQRLLELQNARVPNAEEVF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q68FW7-1", "uniprot_id": "SYTM_RAT", "id": "Q68FW7-1", "name": "Threonine--tRNA ligase, mitochondrial", "aln": "--------------------------MGLCLRWRRLGFPLPGFRRCELHTVREAP--------------------IPTPPHWLAERFGLFEELWTAQVKRLASMTQKKARTIKISLPEGQKVDAVAWNTTPYQLAQQISSTLADTAVAAEVNGELYDLDRPLETDC----HLRFLTFDSPEGKAVFWRSSAHVLGAAAEQHLGAVLCRGPSTESGFYLDFFLGKER---------TVRSTELPTLERICQEIITAAQPFRRLEASRGQLRQLFKDNHFKLHVIEEKVTG-TTATVYGCGMSVDLCQGPHLRHTGQIGALKLLTNSSALWRSSEAPETLQRVSGISFPKAELLRNWEARREEAELRDHRRIGKEQELFFFHELSPGSCFFLPRGTRIYNALVAFIRAEYARRGFSEVKTPTLFSTKLWEQSGHWEHYRAHMFSLKPPGTDGVDSSQSGHPARCPKDTLALKPMNCPAHCLMFAHRPRSWRELPVRLADFGVLHRAEASGSLGGLTRLWRFQQDDAHIFCAPSQLEAEIRGCLDFLRSVYSVLGFSFHLALSTRPPGFLGEPHLWDQAEKVLQQALEEFGEPWNLNPGDGAFYGPKIDVHLHDALGRPHQCGTIQLDFQLPLRFDLQYKGPAGAPE---CPVLIHRAVLGSVERLLGVLAESCGGRWPLWLSPFQVVVIPVRTEQEDYARQVQQCLQAAGLVSDLDADCGLTLSRRVRRAQLAHYNFQFVVGQREQSQMSVNVRTRDNR----QLGERGLAESVQRLLELQDARVPNAEELF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BW92-1", "uniprot_id": "SYTM_HUMAN", "id": "Q9BW92-1", "name": "Threonine--tRNA ligase, mitochondrial", "aln": "--------------------------MALYQRWRCL--RLQGLQACRLHT---AV--------------------VSTPPRWLAERLGLFEELWAAQVKRLASMAQKEPRTIKISLPGGQKIDAVAWNTTPYQLARQISSTLADTAVAAQVNGEPYDLERPLETDS----DLRFLTFDSPEGKAVFWHSSTHVLGAAAEQFLGAVLCRGPSTEYGFYHDFFLGKER---------TIRGSELPVLERICQELTAAARPFRRLEASRDQLRQLFKDNPFKLHLIEEKVTG-PTATVYGCGTLVDLCQGPHLRHTGQIGGLKLLSNSSSLWRSSGAPETLQRVSGISFPTTELLRVWEAWREEAELRDHRRIGKEQELFFFHELSPGSCFFLPRGTRVYNALVAFIRAEYAHRGFSEVKTPTLFSTKLWEQSGHWEHYQEDMFAVQPPGSDRPPSSQSDDSTRHITDTLALKPMNCPAHCLMFAHRPRSWRELPLRLADFGALHRAEASGGLGGLTRLRCFQQDDAHIFCTTDQLEAEIQSCLDFLRSVYAVLGFSFRLALSTRPSGFLGDPCLWDQAEQVLKQALKEFGEPWDLNSGDGAFYGPKIDVHLHDALGRPHQCGTIQLDFQLPLRFDLQYKGQAGALE---RPVLIHRAVLGSVERLLGVLAESCGGKWPLWLSPFQVVVIPVGSEQEEYAKEAQQSLRAAGLVSDLDADSGLTLSRRIRRAQLAHYNFQFVVGQKEQSKRTVNIRTRDNR----RLGEWDLPEAVQRLVELQNTRVPNAEEIF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PJQ9-1", "uniprot_id": "A0A8M9PJQ9_DANRE", "id": "A0A8M9PJQ9-1", "name": "threonine--tRNA ligase", "aln": "---------------------------MVIPVFSRWPVRLAAVRAAGWNCR--------------------------HYGKLVHERLQVFQSLRDRLLKASGSPS---GRDLAIRLADGRTVKGSAGVTSPLQIAR---SERVTGAVVSRVNGELWALSRPLLEDC----ELQLLGFDSLEGKEVVWRTGACVLASVLERVFSAGVCREGVSDTGLYCDYQLQDS-------------SISLLEVEQACKQVAAGKIPITTLELTLQDLKELFQDNAVRLQLAEEQMMG-DTVGVFRCGDSVGVCSGLLLPHTGFLKAFKMLQVSPVTLSGSSEASGILRMIGVSFPSEREREQWEKEQEEARRRDHRRIGKAQELFFFHDVSPGSCFFMPKGAHIYNTLTDFIKSEYRRRGFSEVVTPTLFSTALWERSGHWQHYSENMFSVSS-----------------ETHTFALKPMNCPAHCVMFEQRLRSWREMPIRWADFGALHRNEASGTLGGLTRVRRFCQDDAHIFCTPEQLELEITACLDFVRSVYRVFGFSFHCLLSTRPASSMGDSALWDCAEQQLESSLKLFQERWELNPGDGAFYGPKIDILIRDALGRQHQCATIQLDFQLPIRFNLQYVGADGQMK---RPIMIHRAVLGSLERMIAILAENFGGKWPFWLSPAQVMVVPVGGSSEAYAQQVVSRLREAGFMADIDDDHGNTLNKKIRSAQLAQYNYIFVVGEKESECGTVSVRTRAGQ----QIGQKTLEDVMKTLTQLTETRSN--EELI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P04801-1", "uniprot_id": "SYTC_YEAST", "id": "P04801-1", "name": "Threonine--tRNA ligase, cytoplasmic", "aln": "--------------------------MSASEAGVTEQVKKLSVKDS---SNDAVKPNKKENKKSK-----QQSLYLDPEPTFIEERIEMFDRLQKEYNDKVASMP---RVPLKIVLKDGAVKEATSWETTPMDIAKGISKSLADRLCISKVNGQLWDLDRPFEGEANEEIKLELLDFESDEGKKVFWHSSAHVLGESCECHLGAHICLGPPTDDGFFYEMAVRDSMKDISESPERTVSQADFPGLEGVAKNVIKQKQKFERLVMSKEDLLKMFHYSKYKTYLVQTKVPDGGATTVYRCGKLIDLCVGPHIPHTGRIKAFKLLKNSSCYFLGDATNDSLQRVYGISFPDKKLMDAHLKFLAEASMRDHRKIGKEQELFLFNEMSPGSCFWLPHGTRIYNTLVDLLRTEYRKRGYEEVITPNMYNSKLWETSGHWANYKENMFTFEV-----------------EKETFGLKPMNCPGHCLMFKSRERSYRELPWRVADFGVIHRNEFSGALSGLTRVRRFQQDDAHIFCTHDQIESEIENIFNFLQYIYGVFGFEFKMELSTRPEKYVGKIETWDAAESKLESALKKWGGNWEINAGDGAFYGPKIDIMISDALRRWHQCATIQLDFQLPNRFELEFKSKDQDSESYERPVMIHRAILGSVERMTAILTEHFAGKWPFWLSPRQVLVVPVGVKYQGYAEDVRNKLHDAGFYADVDLTG-NTLQKKVRNGQMLKYNFIFIVGEQEMNEKSVNIRNRDVMEQQGKNATVSVEEVLKQLRNLKDEKRGDNVLA-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VKB0-1", "uniprot_id": "Q9VKB0_DROME", "id": "Q9VKB0-1", "name": "threonine--tRNA ligase", "aln": "MLKLAPQGGRYYSQISRICQWILPKIQTQSKPPKQQQQQQPQLKEQQQHSYATLAAKMKKEKKEKPSGGGDTRKELSPLPKYIEERNVFWEKCKAEYEAELAAKK---REPIKVTLPDGKQVDATSWETTPYEVARGISQGLADNTVISKVNGEVWDLDRVLEGNC----TLQLLKFDDPEAQAVFWHSSAHIMGEAMERIYGGHLCYGPPIENGFYYDMHLEG----------EGISTNDYGAMEGLVKQIVKEKQNFERLEMKKSDLLEMFKYNEFKVRILNEKVTT-DRTTVYKCGSLIDLCRGPHVRHTGKVKALKITKNSSTYWEGKADAETLQRVYGISFPDPKQLKEWEKLQEEAAKRDHRKIGREQELFFFHELSPGSCFFQPRGAHIYNTLMGFIKAEYRKRGFQEVISPNIYNAKLWMTSGHWQHYAENMFSFEA-----------------EKEKFALKPMNCPGHCLIFDNRNRSWRELPLRMADFGVLHRNELSGALTGLTRVRRFQQDDAHIFCAPEQIKSEMKGCLEFLKYVYTIFGFSFQLVLSTRPDNYLGELEQWNDAEKALAESLNEFGMPWKENPGDGAFYGPKIDITIMDALKRAHQCATIQLDFQLPIRFNLSYIADDGEKK---RPVIIHRAILGSVERMIAILTENFAGKWPFWLSPRQVMVVPVGPAYDQYAQSVRDQLHDAGFMSEADCDAGDTMNKKIRNAQLAQFNFILVVGDKERSSNTVNVRTRDNK----VHGEVSVAELITKLQKIRDEFIANEDSF-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: : ** .:: .: : : * * .. : *:* ::*: . :.***: : *.* : :. *.:* *:. *.: *.*::.: ::. * .. :* : *:: : : . :* ::: : * . :* ::*: . : : : :: . *: ** :.:* * : *** : .:*: *. . . : *: *:*** . * ****:**: ****:*:::******: *:*:::**:* ::::** :**:.** :*.::.: ** **** :* .**:.. ...:.*******.**::* * **:**:* * ****.:** * ** * ****: * ********: *:: *: ::*:: :* ::**.*: ***** :*. *: **. * .:*: : *. *.***********: : *** * ***.********* **:*.: . : *::****:***:**: .:*:* .*:**:**** **:*:** : **... . *: **: :: * *:.:::* .*: ::*: ::**::* . :*.:*.* . : : : * :: : ", "identical_positions": 210, "similar_positions": 204, "identity": "26.58%" }, { "cls_id": "homologset.agr.RGD:1308284", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K2P6-1", "uniprot_id": "RFESD_MOUSE", "id": "Q8K2P6-1", "name": "Rieske domain-containing protein", "aln": "MDPEISEQDEEKKKYTSVCVGREEDIRKSERMTAVVHDREVVIFYHKGEYHAMDIRCYHSGGPLHLGEIEDFNGQSCIVCPWHKYKITLATGEGLYQSINPKDPSAKPKWCSKGVKQRIHTVKVDNGNIYVTLSKEPFKCDSDYYATGEFKVIQSSS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZF58-1", "uniprot_id": "D3ZF58_RAT", "id": "D3ZF58-1", "name": "Rieske domain-containing protein", "aln": "MDPEISEQDEEQK---TVCVGREEDIRRSERMTAVVHGREVVIFYHKGEYHAMDIRCYHSGGPLHLGEIEDFNGQSCIVCPWHKYKITLATGEGLYQSIDPKDPSAKPKWCSKGVKQRIHIVTVKNGNIYVTLSKEPFKCDSDYYATGEFKVIQSSS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8TAC1-1", "uniprot_id": "RFESD_HUMAN", "id": "Q8TAC1-1", "name": "Rieske domain-containing protein", "aln": "MNLDGSAQDPEKREYSSVCVGREDDIKKSERMTAVVHDREVVIFYHKGEYHAMDIRCYHSGGPLHLGDIEDFDGRPCIVCPWHKYKITLATGEGLYQSINPKDPSAKPKWCSKGIKQRIHTVTVDNGNIYVTLSNEPFKCDSDFYATGDFKVIKSSS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: : * ** *:: :******:**::*********.*****************************:****:*:.***********************:**************:***** *.*.*********:********:****:****:***", "identical_positions": 128, "similar_positions": 21, "identity": "81.53%" }, { "cls_id": "homologset.agr.RGD:1308285", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q4FZT0-1", "uniprot_id": "STML2_RAT", "id": "Q4FZT0-1", "name": "Stomatin-like protein 2, mitochondrial", "aln": "--MLARAARGTGALLLRGSVQASGRIP---RRASSGLPRNTVILFVPQQEAWVVERMGRFHRILEPGLNVLIPVLDRIRYVQSLKEIVINVPEQSAVTLDNVTLQIDGVLYLRIMDPYKASYGVEDPEYAVTQLAQTTMRSELGKLSLDKVFRERESLNANIVDAINQAADCWGIRCLRYEIKDIHVPPRVKESMQMQVEAERRKRATVLESEGTRESAINVAEGKKQAQILASEAEKAEQINQAAGEASAVLAKAKAKAEAIRILAGALTQHNGDAAASLTVAEQYVSAFSKLAKDSNTVLLPSNPSDVTSMVAQAMGVYGALTKAP--VPGAQN--SSEARRDVQTTD-TSI-EELGRVKLS--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99JB2-1", "uniprot_id": "STML2_MOUSE", "id": "Q99JB2-1", "name": "Stomatin-like protein 2, mitochondrial", "aln": "--MLARAARGTGALLLRGSVQASGRVP---RRASSGLPRNTVILFVPQQEAWVVERMGRFHRILEPGLNVLIPVLDRIRYVQSLKEIVINVPEQSAVTLDNVTLQIDGVLYLRIMDPYKASYGVEDPEYAVTQLAQTTMRSELGKLSLDKVFRERESLNANIVDAINQAADCWGIRCLRYEIKDIHVPPRVKESMQMQVEAERRKRATVLESEGTRESAINVAEGKKQAQILASEAEKAEQINQAAGEASAVLAKAKAKAEAIRILAGALTQHNGDAAASLTVAEQYVSAFSKLAKDSNTVLLPSNPSDVTSMVAQAMGVYGALTKAP--VPGAQN--SSQSRRDVQATD-TSI-EELGRVKLS--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UJZ1-1", "uniprot_id": "STML2_HUMAN", "id": "Q9UJZ1-1", "name": "Stomatin-like protein 2, mitochondrial", "aln": "--MLARAARGTGALLLRGSLLASGRAP---RRASSGLPRNTVVLFVPQQEAWVVERMGRFHRILEPGLNILIPVLDRIRYVQSLKEIVINVPEQSAVTLDNVTLQIDGVLYLRIMDPYKASYGVEDPEYAVTQLAQTTMRSELGKLSLDKVFRERESLNASIVDAINQAADCWGIRCLRYEIKDIHVPPRVKESMQMQVEAERRKRATVLESEGTRESAINVAEGKKQAQILASEAEKAEQINQAAGEASAVLAKAKAKAEAIRILAAALTQHNGDAAASLTVAEQYVSAFSKLAKDSNTILLPSNPGDVTSMVAQAMGVYGALTKAP--VPGTPDSLSSGSSRDVQGTD-ASLDEELDRVKMS--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W1F7-1", "uniprot_id": "Q9W1F7_DROME", "id": "Q9W1F7-1", "name": "", "aln": "MSRFLLNKRFVPSLVQQDFLLAGSWIPSQSRRGKASTPINMCVMFVPQQEAWVVERMGRFHRILDPGLNILVPVADKIKYVQSLKEIAIDVPKQSAITSDNVTLSIDGVLYLRIIDPYKASYGVEDPEFAITQLAQTTMRSELGKMSMDKVFRERESLNVSIVDSINKASEAWGIACLRYEIRDIRLPTRVHEAMQMQVEAERRKRAAILESEGVREAEINIAEGKRKSRILASEAERQEHINKASGEAAAIIAVADARARSLLAIAKSLSHLDGQNAASLTLAEQYIGAFKKLAKTNNTMILPSNPGDVNGFVAQALAVYNHVSNSNQATKSSENVKGVGACLNAKSVEYKELQEDKSSVKMNIE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * . :*: :. : *.. * **..:. * * ::********************:****:*:** *:*:********.*:**:***:* *****.*********:*************:*:**************:*:***********..***:**:*::.*** ******:**::*.**:*:*************::*****.**: **:****::::*******: *:**:*:***:*::* *.*:*.:: :* :*:: :*: *****:****:.**.**** .**::*****.**..:****:.**. :::: . .: : . : :.: .: .: *: . **:. ", "identical_positions": 208, "similar_positions": 105, "identity": "56.83%" }, { "cls_id": "homologset.agr.RGD:1308286", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q3KRD0-1", "uniprot_id": "SYDM_RAT", "id": "Q3KRD0-1", "name": "Aspartate--tRNA ligase, mitochondrial", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MYLGSWLN--------RLGRG-----------------LSRPIGKTKQPIWGSLSR---------------------------------------------------------------------------------SLTLSSQR-VPEFSSFVARTNTCGELRSSHLGQEVTLCGWIQYR-----RQNTFLVLRDCHGLVQILIPQDESAASVRRTLCEAPVESVVRVSGTVIARPLGQENPKMPTGEIEIKAKTAELLNACKK-LPFEIKDFVKKTEALRLQYRYLDLRSSQMQHNLRLRSQMVMKMREYLCTLHGFVDIETPTLFKRTPGGAKEFLVPSREPGR-----FYSLPQSPQQFKQLLMVGGLDRYFQVARCYRDEGSRPDRQPEFTQIDIEMSFVDQTGIQHLVEGLLHYSWPED-------------------KDPLVAPFPSMTFAEALATYGTDKPDTRFGMKIVDISDVFRN-TEIRFLQDALAKPQGTVKAICVHEGAKYLRKEDIEFIRKFAAHHFSQEVLPIFLNARKNWSSPFAKFITEEERLELTRLMEIQEDDMVLLTAG--QHEKACSLLGKLRLECADLLETRGLALRDPA-LFSFLWVLDFPLFL---------------AKEESPTELESAHHPFTAPHPGDIHLLYTEPE---KVRGQHYDLVLNGNEIGGGSIRIHDAQLQRYILETLLKED--VKLLSHLLQALDYGAPPHGGIALGLDRLVCLVTGAPSIRDVIAFPKSYRGHDLMSNAPDTVSPEDLKPYHIHVSWP--------------TDSEER-ASATPSKYLSS---------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BIP0-1", "uniprot_id": "SYDM_MOUSE", "id": "Q8BIP0-1", "name": "Aspartate--tRNA ligase, mitochondrial", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MYLGFWLS--------RLCRG-----------------LSRPIGKTMRPIWGSLSR---------------------------------------------------------------------------------NLALSSQR-IPEFSSFVARTNTCGELRSSHLGQEVTLCGWIQYR-----RQNTFLVLRDCHGLVQILIPQDESAASVRRILCEAPVESVVRVSGTVISRPPGQENPKMPTGEIEIKVKTAELLNACKK-LPFEIKDFVKKTEALRLQYRYLDLRSFQMQYNLRLRSQMVMKMREYLCNLHGFVDIETPTLFKRTPGGAKEFLVPSREPGK-----FYSLPQSPQQFKQLLMVGGLDRYFQVARCYRDEGSRPDRQPEFTQIDIEMSFVEQTGIQRLVEGLLQYSWPGD-------------------KDPLVTPFPSMTFAEALATYGTDKPDTRFGMKIVDVSDVFRN-TELRFLQDALAKPQGTVKAICVHDGAKYLRKEDIEFIRKFAVHHFSQEVLPIFLNAKKNWSSPFAKFIMEEERLELARSMEIQEEDIVLLTAG--EHEKACSLLGKLRLECADLLEMRGAVLRDPA-VFSFLWVVDFPLFL---------------AKEESPTELESAHHPFTAPNSSDIHLLYTEPE---KVRGQHYDLVLNGNEIGGGSVRIHDAQLQRYILETLLKED--VKLLSHLLQALDYGAPPHGGIALGLDRLVCLVTGAPSIRDVIAFPKSYRGQDLMSNAPDSVSPEELKPYHIHVLWP--------------ADSEEESASATPSKHLSS---------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6PI48-1", "uniprot_id": "SYDM_HUMAN", "id": "Q6PI48-1", "name": "Aspartate--tRNA ligase, mitochondrial", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MYFPSWLS--------QLYRG-----------------LSRPIRRTTQPIWGSLYR---------------------------------------------------------------------------------SLLQSSQRRIPEFSSFVVRTNTCGELRSSHLGQEVTLCGWIQYR-----RQNTFLVLRDFDGLVQVIIPQDESAASVKKILCEAPVESVVQVSGTVISRPAGQENPKMPTGEIEIKVKTAELLNACKK-LPFEIKNFVKKTEALRLQYRYLDLRSFQMQYNLRLRSQMVMKMREYLCNLHGFVDIETPTLFKRTPGGAKEFLVPSREPGK-----FYSLPQSPQQFKQLLMVGGLDRYFQVARCYRDEGSRPDRQPEFTQIDIEMSFVDQTGIQSLIEGLLQYSWPND-------------------KDPVVVPFPTMTFAEVLATYGTDKPDTRFGMKIIDISDVFRN-TEIGFLQDALSKPHGTVKAICIPEGAKYLKRKDIESIRNFAADHFNQEILPVFLNANRNWNSPVANFIMESQRLELIRLMETQEEDVVLLTAG--EHNKACSLLGKLRLECADLLETRGVVLRDPT-LFSFLWVVDFPLFL---------------PKEENPRELESAHHPFTAPHPSDIHLLYTEPK---KARSQHYDLVLNGNEIGGGSIRIHNAELQRYILATLLKED--VKMLSHLLQALDYGAPPHGGIALGLDRLICLVTGSPSIRDVIAFPKSFRGHDLMSNTPDSVPPEELKPYHIRVSKP--------------TDSKAERAH------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M9PDL2-1", "uniprot_id": "M9PDL2_DROME", "id": "M9PDL2-1", "name": "", "aln": "MLLISRTLWRSHQRLQLQQQLVHSASSGGFLADRHIRHRSTPDSLFSAKEPADCGHIMSGRYRGGGGGRFGGRGGGGYADGGGYNDFDNYRGGGGPGFNDNFGPGPGPNPFNMGGPNISGNELMQLMSAMASNFNMNSQPPQPMRQSCGELRNHHCGLFVELSGRLIKKRVNRFAELRDRNGGACQLVVLEDKHPRVARRMNNMPENTTLTIVGLVMRRPHNSCNQTMPTGEIEVEVQDILNIHFPAGGTKRAGDKRTYSTMVQQQSNLGITSTEYKIAKNENILKYFENRDLTCNDLRRDDVGKTVTLVGWIPSTKNNKFLQLKDGYGQTQLMIEDQSLSDTFLSTPEQTVIQIVGKVLGRPKANVNLKYDTGEVEVSVTSVKVLNPDDPYDGPIKAKEKKQKFSIDDLEAEEAAAEASANLTSNNGESTEDSAEASTTANASLIAEQRAKVADTNKFADRTHNCGELTSNDINEKVVICGWLEFQ-----RMNKFFILRDAYGQTQVLLSP-KTYGLEEYAETGVPIESIVRVEGTVIPRPAATINPKMQTGHVEVEADKVVVLNPAKKNLPFEIRKFNRAGERLRLTHRYLDLRFNDMQHNLRLRSAVIMKMREYLINYLGFVEVETPTLFRRTPGGAQEFVVPTRKAGH-----FYSLVQSPQQFKQMLMSGGIDRYFQVARCYRDEATRPDRQPEFTQLDIELSFTSRDDIMQLIEETLRYSWPKD-------------------FPRLQTPFRRITYEEAMEKYGNDKPDTRFGFLLNNVSEIIEKSDEFKEKYDDLG-----AYAIVVRASEAFWNGAARKHYESLG-KEFKGTLFVRKFGPTKDVQEKLGKLLGEDVATEVADKFDLEENDLLFLGIG--SKVETRELLGRIRLDYQDFLVEN-AKIKKPN-DFRFLWVIDFPLFE---------------RNRETN-QLESVHHPFTLPHSDDLENFATSCENLESIRSQAYDLVLNGQEVGGGSIRIHDRDMQHFILEQILKIP--HDHLSHLLSALESGCPPHGGIALGLDRLIAILCRARSIRDVIAFPKSLNGRDPLSNAPVPISDEEMRLYHLSVVDEEEPSTNNTSHEQEDDDPDQERAPPSPMSATSESEQPQINVDIKQEPEGLNEDFAPESPATKSTVKADPDEPSPSNPLASEAATPARARRTVKKKV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P15179-1", "uniprot_id": "SYDM_YEAST", "id": "P15179-1", "name": "Aspartate--tRNA ligase, mitochondrial", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLARSRVCLQTITRRLAD------------------------------------------------------------------------------------FPEANAIKKKFLFRKDTSTIKQLKGLSSGQKIVLNGWIEQKPKRVGKNLIFGLLRDSNGDIIQLVDN-------KSLLKGFTLEDVVQAVGILSLKRKLSNE---DADEYEVQLEDITVLNASNK-KPAQMQDFKLS-AIYPPEFRYLQLRNPKYQDFLKKRSSISKEIRNSFNNFD-FTEVETPMLFKATPEGAREFLVPTRTKRSDGKPSFYALDQSPQQYKQLLMASGVNKYYQMARCFRDEDLRADRQPEFTQVDMEMAFANSEDVMKIIEKTVSGVWSKFSKKRGLLTLDSKGTLVPAKKENGTVSIFRMTYEQAMTSYGIDKPDLRAPDLKIINLGEFNAFSHLNKKFPVFEVIILRSAFSNMEEYKERWS--FLTNNSNYNYRVPIVLPIENDEQANSNWFENFHAIATFENPHLITKFLKLKKGDIVCGCTREPNHSIFENPTPLGRLRQLVLQSEHGKNIYHAVNKDVASWIVDFPLFSPVIIEDKSGKKEKLAYPEYEKDRLCSTHHPFTMVKLKDYEKLEKTPE---KCLGRHYDLVVNGVELGGGSTRIHDPRLQDYIFEDILKIDNAYELFGHLLNAFDMGTPPHAGFAIGFDRMCAMICETESIRDVIAFPKSITGADLVVKSPSVIPESILEPYNIKYSNSKK---------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : * . : . * * . :* . .:::.: **:: : : * :*** * :: . .:*.:*:. * : : : :.. *:: . :**..:* * :::.* .***:** . * *: ** : ::*: : . *.::*** **: ** **:**:**:* **:* *****:**:** .*:::*:*:***:*** *.********:*:*::*.. .: ::* : *. ..: :*: :.: .** **** * :. .: : : . : . : . . : . : :. :: *:: .: . ** : . : .. *::***** . .* *.***** : * . : . : . .: ****:** *:**** ***: :* :*: :** . :.***.*:: * ***.*:*:*:**: .:: : *********** * * : ::* :. . :. *:: ", "identical_positions": 151, "similar_positions": 169, "identity": "12.61%" }, { "cls_id": "homologset.agr.RGD:1308287", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "F7ENQ2-1", "uniprot_id": "F7ENQ2_RAT", "id": "F7ENQ2-1", "name": "RING finger protein 32", "aln": "MLKNKDRSSKKSNLAVSAVALQDHILRDLQLGHLSVADPCKTKVQKKENKSQSLRKGSAAMMDTGLRKTAEGPKGEDPEKEYVLDPTPPPLTLAQKLGLLALPPLPLSSDEWEKVKQRSLLQGDSMQPCPICKEEFELQPQVLLSCSHVFHRACLQAFEKFTNRKTCPLCRKNQYQTRVIHDGARLFRVKCATRIQAYWRGYIVRKWYRNLRKMIPPTDAKLRRKFFEEKFTEISHRILCSYNTNIDELFSEIDVCLAVNRSILQQLDERCGQEITEEDWEKIQAQAAHHEIYECSICLTPLFFHCDGRQAAAGTSSQHPRETVLLSCAHLFHNACLLALEEFSLGDNAPFNVCPLCRSCYQKKIVEY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JIT1-1", "uniprot_id": "RNF32_MOUSE", "id": "Q9JIT1-1", "name": "RING finger protein 32", "aln": "MLRNKDRSSNKGNLAVTAVALQDHLLHDLQLGHLSVADPCKIKARKKEKKSKSLKRDATAIIDTGLRKSTEGPNMEDPEKEYVLDPTPPPLTLAQKLGLLPPPPLPLSSDEWERVKQRSLLQGDSIQPCPICKEEFELHPQVLLSCSHVFHRACLQAFEKFTNKKTCPLCRKNQYQTRVIHDGARLFRVKCATRIQAYWRGYIVRKWYRNLRKIIPPSDAKLRRKFFEEKFTEISHRILCSYNTNIDELFSEIDVCLAVNRSILQQLDERCGQIITKEDWEKIQAQAAHHEIYECSICLTPLSFHGDGRQAAIGTSSQRPRETVLLSCAHLFHNACLLALEEFSLGDNAPFHVCPLCRSCYQKKIVEC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H0A6-1", "uniprot_id": "RNF32_HUMAN", "id": "Q9H0A6-1", "name": "RING finger protein 32", "aln": "MLKNKGHSSKKDNLAVNAVALQDHILHDLQLRNLSVADHSKTQVQKKENKS--LKRDTKAIIDTGLKKTTQCPKLEDSEKEYVLDPKPPPLTLAQKLGLIGPPPPPLSSDEWEKVKQRSLLQGDSVQPCPICKEEFELRPQVLLSCSHVFHKACLQAFEKFTNKKTCPLCRKNQYQTRVIHDGARLFRIKCVTRIQAYWRGCVVRKWYRNLRKTVPPTDAKLRKKFFEKKFTEISHRILCSYNTNIEELFAEIDQCLAINRSVLQQLEEKCGHEITEEEWEKIQVQALRRETHECSICLAPLSAAG-GQRVGAGRRS---REMALLSCSHVFHHACLLALEEFSVGDRPPFHACPLCRSCYQKKILEC", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:**.:**:*.****.*******:*:**** :***** .* :.:***:** *::.: *::****:*::: *: **.********.************: ** ********:***********:************:************:***********:************************:**.********* :********** :**:*****:****:*****************:***:*** ***:***:****:*:**: **:*:*****.** ::* :******:** *::.. * * ** .****:*:**:**********:**..**:.************:* ", "identical_positions": 270, "similar_positions": 68, "identity": "73.37%" }, { "cls_id": "homologset.agr.RGD:1308289", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M1N6P0-1", "uniprot_id": "A0A8M1N6P0_DANRE", "id": "A0A8M1N6P0-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------MNRRLYPISFFAFFVALLLFILKIASADLSYNIPEETKRHYVIANIAKDFKMDVKQLSARKARIDPEDSSKRYCDINPNTGDLFVAETIDREELCGSRMSCILNYELVLENPLDVHRIIFQIQDINDNTPRFPNERINFEIRESAVKGQRFRLDEAHDSDIGKNSINDYSLEKNEHFVLTVQ-TADEEKYAELVLEKELDREQQKEMDLILTATDGGLPQRSGTAVIHITVLDANDNVPVFDQPIYKVTLAENTPSGTDIIRVSATDADEGPNGEVTYEFSRISDK-TAKLFSIDKTTGQILVKGEIDYESEKNYELGIQAKDASGLASIAKVIIDITDVNDNPPRIILKSLNNPIPENSEPGAEVGIINVQDKDSGENRQIRCSVQQNVPFKLNPSVKNYFSLVTTKALDREKESDYNITITATDGGSPPLSTSMTIHLFVSDVNDNPPVFEQQAYSAYINENNKADTSVCSVSANDPDWRQNGTVLYSLVPSEVSGVPVSSFLSINGDTGVIHAVRSFDYEQFRNFSVKVVARDNGSPPLSSNVTVKVFITDENDNSPQILYPVP-DGKTLMTEMVPKATLSGSLVSKVIAVDADSGQNAWLSYQILKSTDPGLFTIGLHSGEIKTQRDISESDNMKQNLVISVKDNAQPSLSTTCVVNLLISDNLSEVP-ELKDMS-YEDN-NSKLTSYLIIALVSVCTFFLTFIILMLAVKFCHRRKPRLLFDGAVAVPSAYLPPNYADVDGAGTLRSSYNYDAYLTTGSRTSDFKFVSSY-NENTLPASGTLNKEHNIHFGSSIITLDVTGDKVEQKPPNTDWRFPPNQRPGPSG------------------AGARPEEAGAGAGVIAGTGPWPNPPTEAEQLQAMMAAANASEA---------------TATLGPRYNLQYGPDYRQNVYIPGSTATLTANPQQQVLQQALPPPQALPPTEAPKAAQTPASKKKPTKKDKK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1N6A8-1", "uniprot_id": "A0A8M1N6A8_DANRE", "id": "A0A8M1N6A8-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------MEYALFWGRFFACFVAVILLLPITVCADLNYNIPEETKSQYVIGNIAKDLGIDVKQLSARKSRIDTEDISKRYCDINMKTGDLIVAETIDREELCGSRMSCFLNYELVLENPLDVHRIIFQIQDINDNAPRFPNERINFEITESADKGQRFRLHEAHDSDIGRNAVNGYLLEKNNHFYLNVHDTAYGGKYAELVLEKELDREQQKEMDLILTATDGGSPQRSGTAVIHITVLDANDNVPVFDQPVYKVTLAENTPSGTEIIRVSATDADEGPNGEVTYEFSRISDK-ASKQFSIDKKTGQILVTEKIDYESEKNYEIGIHAQDGSGLASTATVIIDITDVNDNPPRIILKSLNNPIPENSEPGAEVGIINVQDKDSGENRQIRCSVQQNVPFKLNPSVKNYFSLVTTKALDREKESDYNITITATDGGSPPLSTSMTIHLFVSDVNDNPPVFEQQAYSAYINENNKVGTSVCSVSANDPDWRQNGTVLYSLVPSEVSGVPVSSFLSINGDTGVIHTVRSFDYEQFRNFSVKVVARDNGSPPLSSNVTVKVFITDENDNSPQILYPVP-DGKTLMTEMVPKATLSGSLVSKVIAVDADSGQNAWLSFQILKSTDPGLFTIGLHSGEIKTQRDISESDNMKQNLVISVKDNGQPSLSTTCVVNLLISDNLSEVP-ELKDMS-YEDN-NSELTSYLIIALVSVCTFFLTFIIMMLAVKFCHRRKPRLLFDGAVAVPSAYLPPNYADVDGAGTIRSSYNHDAYLTTGSRTSDFKFVSSY-NENTLQAGGSLKSVQSDSFGAHVVTLINTEEAEEQKPPNTDWRFPPNQRPGPSG------------------AGARPEEAGAGAGVIAGTGPWPNPPTEAEQLQAMMAAANASEA---------------TATLGPRYNLQYGPDYRQNVYIPGSTATLTANPQQQVLQQALPPPQALPPTEAPKAAQTPASKKKPTKKDKK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1N6G0-1", "uniprot_id": "A0A8M1N6G0_DANRE", "id": "A0A8M1N6G0-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------MAKTSKLCLGKWRLWITSLLFC--VTAADVRYSVPEETKTKFVIGNLSKDVNLDYNRLRFRKARLDYQG-DRRYCEIDLDSGNLFVSERIDREMLCGTASPCIMHFEFILENPLELHNIALEVQDVNDNPPVFPKGSIKLEISEGAPTGSKLQLTRARDLDVGINSVQTYILSQNKHFVLDTK--SSKDRYVDIVLKNSLDRETRGEHSLILSAVDGGNPPNSGTVVIEVVVIDMNDNAPLFLQPLYNARLSENSALGTSVIKITATDEDEGANGEIKYYINHLSDN-TKQLFKIDENYGEISVIGQLDHEKASSYEVEVQAEDGGGQTGHCKVVIEIDDVNDNAPVISVKSLKNKIPENTTPGTEIAVINVKDQDSGENSRISCSISPNLPFQLQPYIKSYFILTTSSSLDREQIDNYNVTIIATDGGIPPLFSNISLNIQVSDVNDNSPRFELQSYFIYISENKQAGTSVCSVSANDPDWRQNGTVLYSLVPSEVNGVPMSSFLSINGDTGVIHTVRSFDYEQFRNFSVKVVARDNGSPPLSSNVTVKVFITDENDNSPQILYPVP-DGKTLMTEMVPKATLSGSLVSNVIAVDADSGQNAWLSYQILKSTDPGLFTIGLHSGEIKTQRDISESDNMKQNLVISVKDNGQPSLSTTCVVNLLISDNLSEVP-ELKDMS-YEDN-NSKLTSYLIIALVSVCTFFLTFIILMLAVKFCHRRKPRLLFDGAVAVPSAYLPPNYADVDGAGTIRSSYNYDAYLTTGSRTSDFKFVSSY-NENTLPAGGILDKSK---IDFNMLRLSDVGECTEQKPPNTDWRFPPNQRPGPSG------------------AGARPEEAGAGAGVIAGTGPWPNPPTEAEQLQAMMAAANASEA---------------TATLGPRYNLQYGPDYRQNVYIPGSTATLTANPQQQVLQQALPPPQALPPTEAPKAAQTPASKKKPTKKDKK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1N6D6-1", "uniprot_id": "A0A8M1N6D6_DANRE", "id": "A0A8M1N6D6-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------MKTMLDAMIQHSVLILTLLVYIARGQVSYSIPEEMAKGSMVGNIAQDLGLDLQRLKSGKARIFSRD-STEYIELNRNTGLLLIKEKMDRESLCAKTTPCALHLQMILDNPMELYTITVEITDINDNAPNFQKRDFKFEISESAMVGARFMLGKAFDPDVGTNSLQSYSLKPTDKFRLELQSQADGSKNVEMILQKALDREMQSSFTLLLEAFDGGDPVLSGTVQIHIAVLDINDNAPVFMQKEYKATATEEAPKGSILTVVSATDTDEGSNSEVTYYISDTMDSVMADMFLVNEQTGELILNGHFDYEKVSHYELTIHAKDQGGLSNACKVIIDVLDVNDNSPSINILSSSHSVSEGSKFGTVIAMLNVDDLDSGASGQVQCVMSEEIPFVIKSQSSNFFSLQTEQELDRERETEYNISVICSDEGVPSLSSSVSLTVQISDVNDNPPVFKKSNYEAFVMENNTPGLSIFTVKASDADWNQNARVSYILEDSTVSGVSVSSYVSVHPDSGLITAVRSFDYETLKDFHFRVKAQDGGSPPLSSNVTVKVTVQDQNDNAPQVLYPVQ-TGTSVVAEIVPRAADVGYLVTKVVAVDVDSGQNAWLSYKLQKAPDRALFEVGLQNGEIRTVRQVTDKDAVKQKLTVVVEDNGQPSRSAVVSINVAVADSFPEVLSEFTDFT-HEKQYNDSLTFYLVLALAAVSFLFITCVVVIISVKIYRWRQSRFLYQSNLPVIP-YYPPHYADTGVTGTLPHGYNYEVCMTTDSRKSDCKFSTLG-GQNVLVVDPSFAETMKHTIKKNSS-IDDLQSTESQKPPNTDWRFPPNQRPGPSG------------------AGARPEEAGAGAGVIAGTGPWPNPPTEAEQLQAMMAAANASEA---------------TATLGPRYNLQYGPDYRQNVYIPGSTATLTANPQQQVLQQALPPPQALPPTEAPKAAQTPASKKKPTKKDKK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1N6Q0-1", "uniprot_id": "A0A8M1N6Q0_DANRE", "id": "A0A8M1N6Q0-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------MAFFVMWHGAVFFMILSRYAVKGQISYSIPEEIPKGSIVENNSQGLGLDLKRLNSGKARIFAGD-NRRFVGLNKEKGILLTEEKIDREALCAKTTPCASHLQLILENPMQKYDVTVEIIDINDNAPSFPKGEIRFEISETAVTGARFMLENPIDLDVGTNSHLSYSLKPTDNFILSSQGQTDGDKNMEMVLQKALDRENKEKLSLMLTAVDGGEPSLTSTVRIHVTVLDANDNPPVFSQRVYKATFAEITPKDTVIASVSASDADEGSNAIITYYMSSTGD--VNDLFTVDTRSRDIRLKGSADFEKASRYQFNIQARDQGGLSDSCKVIIDLTDINDNKPIISIVSMSNSISEQSRPGTVVAMLNVNDFDSGMNGRVHCYRNDNIPFTIAS-SSSFFSLQTEQELDREKEAEYNISVICSDEGVPALSSSVSLRVQISDVNDNAPVFEKSNYEAFVVENNTPGLSIFTVKASDADWNQNARVSYILEDSIVNGVSISSYVSVHPESGLITAVRSFDYETLKDFHFRVKAQDGGSPPLSSNVTVKVTVQDHNDNAPQVLYPVQ-TGASVVAEIVPRAADVGYLVTKVVAVDVDSGQNAWLSYKLQKATDRALFEVGLQNGEIRTVRQVTDKDAVKQKLTVVVEDNGQPSRSAVVSINVAVADSFPEVLSEFTDFT-HEKQYNDSLTFYLVLALAAVSFLFITCVVVIISVKIYRWRQSRFLYQSNLPVIP-YYPPHYADTGVTGTLPHGYNYEVCMTTDSRKSDCKFSTLG-RQNVLVVDPSFTETMQHTIKKKCS-IDGLRITKSQKPPNTDWRFPPNQRPGPSGQHRFHTLQQRWTPYEKSRAGARPEEAGAGAGVIAGTGPWPNPPTEAEQLQAMMAAANE-----------------------ERNTHRFETSGRK------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9Y5G6-1", "uniprot_id": "PCDG7_HUMAN", "id": "Q9Y5G6-1", "name": "Protocadherin gamma-A7", "aln": "---------------------------------------------------------------------------------------------------MAAQPRGG------------DYRGFFLLSILLGTPWEAWAGRILYSVSEETDKGSFVGDIAKDLGLEPRELAERGVRIISRG-RTQLFALNQRSGSLVTAGRIDREEICAQSARCLVNFNILMEDKMNLYPIDVEIIDINDNVPRFLTEEINVKIMENTAPGVRFPLSEAGDPDVGTNSLQSYQLSPNRHFSLAVQSGDDETKYPELVLERVLDREEERVHHLVLTASDGGDPPRSSTAHIQVTVVDVNDHTPVFSLPQYQVTVPENVPVGTRLLTVHAIDLDEGVNGEVTYSFRKITPK-LPKMFHLNSLTGEISTLEGLDYEETAFYEMEVQAQDGPGSLTKAKVLITVLDVNDNAPEVTMTSLSSSIPEDTPLGTVIALFYLQDRDSGKNGEVTCTIPENLPFKLEKSIDNYYRLVTTKNLDRETLSLYNITLKATDGGTPPLSRETHIFMQVADTNDNPPTFPHSSYSVYIAENNPRGASIFLVTAQDHDSEDNAQITYSLAEDTIQGAPVSSYVSINSDTGVLYALQSFDYEQLRELQLRVTAHDSGDPPLSSNMSLSLFVLDQNDNPPEILYPALPTDGSTGMELAPRSAEPGYLVTKVVAVDKDSGQNAWLSYLLLKASEPGLFAVGLYTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSIPEVLADLGSLEPSDGPYNYDLTLYLVVAVATVSCVFLAFVLVLLALRLRRWHKSRLLQASEGGLAN-VPTSHFVGMDGVQAFLQTYSHEVSLTADSRKSHLIFPQPN-YVDMLISQESCEKNDSLLTSVDFQECKENLPSIQQAPPNTDWRFSQAQRPGTSG-----------------------SQNGD------DTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTN---------------AAGKRDGKAPAGGNGNKKKSGKKEKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Y5H3-1", "uniprot_id": "PCDGA_HUMAN", "id": "Q9Y5H3-1", "name": "Protocadherin gamma-A10", "aln": "---------------------------------------------------------------------------------------------------MAAQRNRSKES--------KDCSGLVLLCLFFGIPWEAGARQISYSIPEELEKGSFVGNISKDLGLAPRELAERGVRIVSRG-RTQLFSLNPRSGSLITAGRIDREELCAQSARCVVSFNILVEDRVKLFGIEIEVTDINDNAPKFQAENLDVKINENVAAGMRFPLPEAIDPDVGVNSLQSYQLSPNKHFSLRVQSRANGVKYPELVLEHSLDREEEAIHHLVLTASDGGDPLRSGTVLVSVTVFDANDNAPVFTLPEYRVSVPENLPVGTQLLTVTATDRDEGANGEVTYSFRKLPDT-QLLKFQLNKYTGEIKISENLDYEETGFYEIEIQAEDGGAYLATAKVLITVEDVNDNSPELTITSLFSPVTEDSPLGTVVALLNVHDLDSEQNGQVTCSILAYLPFKLEKSIDSYYRLVIHRALDREQVSSYNITVTATDGGSPPLSTEAHFMLQVADINDNPPTFSQVSYFTYIPENNARGASIFSVTALDPDSKENAQIIYSLAEDTIQGVPLSSYISINSDTGVLYALRSFDYEQFHELQMQVTASDSGDPPLSSNVSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLLKASEPGLFAVGEHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSIPQVLADLGSFESPANSETSDLTLYLVVAVAAVSCVFLAFVIVLLAHRLRRWHKSRLLQASGGGLTG-VSGSHFVGVDGVRAFLQTYSHEVSLTADSRKSHLIFPQPN-YADTLISQESCEKNDPLSLLDDSKFPIEDTPLVPQAPPNTDWRFSQAQRPGTSG-----------------------SQNGD------DTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTN---------------AAGKRDGKAPAGGNGNKKKSGKKEKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6G1R8-1", "uniprot_id": "A0A8I6G1R8_RAT", "id": "A0A8I6G1R8-1", "name": "", "aln": "MREGAAERRRGHRRPMLLPFLLPLFCPALSEQIRYKIPEEMPTGSVVGNLAKDLGFGVQELPTRKLRISSEKPYFTVSSESGELLVSSRLDREQICGKKLVSKQRGAKKMREGAAERRRGHRRPMLLPFLLPLFCPALSEQIRYKIPEEMPTGSVVGNLAKDLGFGVQELPTRKLRISSE---KPYFTVSSESGELLVSSRLDREQICGKKLVCSLEFEAVAENPLNFYHVSVELEDINDHTPKFAHTSFELQISESAQPGTRFILEVAEDADIALNSLQNYKLSLSPSFSLVNKEKQDGRKYPELVLEKTLDREQQSYYRLVLTALDGGDPPLSSTTELRIQVTDANDNPPVFDQEVYRVRLPENVPPGTTVARVTATDKDEGVNSEITYSFHRAG-----QVFGLNSNSGEITTQRTLDFEETKEYSIVVEARDGGGLVAQCTVEINIQDENDNKPEITVHSLLETIPENAPPGTLISLIKIHDRDSGENGEVNCRLDSEAPFKIISSSKNSYKLVTDRTLDRELTPEYNVSIMATDGGKPPLSSSTKVTLHVGDVNDNAPLFHQASYLVYIAENNPPGASIAQVSASDPDLGSNGHVSYSIIASDLEPKSLWSYVTVNAQSGVVFAQRAFDHEQLRSFQLTLQARDQGSPALSANVSMRVLVGDRNDNAPRVLYPALEPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLSYHVLQASDPGLFSLGLRTGEVRTARALGEKDAARQRLLVGVRDGGQPPLSATATLLLVFADSLQEALPDLSDRSLPPDPQ-AELQFYLVVALALISVLFLLAVILAIALRLRHSSSPSAWNCFQPGFCS-ESKPVVFPNYSEGTLPYSYNLYGAHAGKTECNFLKCSEPLSSGQGLLCPESS---GALFPLCDSSEPTS-HPEPPQAPPNTDWRFSQAQRPGTSG-----------------------SQNGD------ETGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGTGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTN---------------AAGKRDGKAPAGGNGNKKKSGKKEKK", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : *.:.** .: : ::.. : ..* *: :. .* *. :*** :*. * : : :: :. . : .:: *:**: * * : .:* * . * :: * . * *:. *: * *. . * * : : :::*:. **** . *:* * *** * :.*. : : * * **: *:* *.. .* . .: : : * * *** *. :.* : * :: :: *.*. *.. :.*.* . ..* * : * *** * : : * :.* : *: :.:: :.* ** . .: * ** : .. : * **** **::: .:* * *.* . . : :.* ***.* * * :: **: . *: *.* * * .*. : * : . :. .: *::::: ::*:: : ::**:* ::.: . : * * *.*.**:*::: : : *.***.*.:***. . : ::.*::: * **::*:*** ***:*****: : ::.: .** :* .**::* * : : * :* * : *.* .**. *:. : : .:*.: :. :: . .* **::*:. :. .*: ::: :: :: : .. . . :: *. : :. . : * * ********. ****.** .: * **.*** ::* ****: *: : . :. .. *: ", "identical_positions": 192, "similar_positions": 257, "identity": "17.6%" }, { "cls_id": "homologset.agr.RGD:1308290", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "O75152-1", "uniprot_id": "ZC11A_HUMAN", "id": "O75152-1", "name": "Zinc finger CCCH domain-containing protein 11A", "aln": "MPNQGEDCYFFFYSTCTKGDSCPFRHCEAAIGNETVCTLWQEGRCFRQVCRFRHMEIDKKRSEIPCYWENQPTGCQKLNCAFHHNRGRYVDGLFLPPSK--------------TVLPTVPESPEEEVKASQLSVQQNKLSVQSNPSPQLRSVMKVESSENVPSPTHPPVVINAADDDEDDDDQFSEEGDETKTPTLQPTPEVHNGLRVTSVRKPAVNIKQGECLNFGIKTLEEIKSKKMKEKSKKQGEGSSGVSSLLLHPEPVPGPEKENVRTVVRTVTLSTKQGEEPLVRLSLTERLGKRKFSAGGDSDPPLKRSLAQRLGKKVEAPETNIDKTPKKAQVSKSLKERLGMSADPDNEDATDKVNKVGEIHVKTLEEILLERASQKRGELQTKLKTEGPSKTDDSTSGARSSSTIRIKTFSEVLAEKKHRQQEAERQKSKKDTTCIKLKIDSEIKKTVVLPPIVASRGQSEE-PAGKTKSMQEVHIKTLEEIKLEKALRVQQSSESSTSSPSQHEATPGARRLLRITKRTGMKEEK--NLQEGNEVDSQSSIRTEAKEASGETTGVDITKIQVKRCETMREKHMQKQQER-----EKSVLTPLRGDVASCNTQVAEKPVLTAVPGITRHLTKRLPTKSSQKVEVETSGIGDSLLNVKCAAQTLEKRGKAKPKVNVKPSVVKVVSSPKLAPKRKAVEMHAAVIAAVKPLSSSSVLQEPPAKKAAVAVVPLVSEDKSVTVPEAENPRDSLVLPPTQSSSDSSPPEVSGPSSSQMSMKTRRLSSASTGKPPLSVEDDFEKLIWEISGGKLEAEIDLDPGKDEDDLLLELSEMIDS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LL44-1", "uniprot_id": "A0ABK0LL44_RAT", "id": "A0ABK0LL44-1", "name": "C3H1-type domain-containing protein", "aln": "MPNQGEDCYFYFYSTCTKGDSCPFRHCEAALGNETVCTLWQEGRCFRQVCRFRHMEIDKKRSEIPCYWENQPMGCQKLNCAFHHNRSRYVDGLFLPPSKSEIGFDSKREQLLFTVLPTVPESQEEEVKTSQLMVQQNKLSVQSNPCPQLRSVMKVESSENVPSPTHPPVVINAADDDEDDDDQFSEEGDESKTPALQPTTDAHNGLRVASTRKPGASLKPGDSLNFGIKTLEEIKSKKMKEKSKKQGEGSSGMSSVLHQPQPNPGPEKENVRTVVRTVTLSSKQ-EEPLVRLSLTERLGKRKLPGGGDNDPPLKRSLAQRLGKKVEAPETNIDKAPKK-----------------------ERVNKTGEIHVKTLEEILLERANQKRGELQTKLKTEEPSGAEDSPSGTKSSS-VRIKTFSEVLAEKKHRQQEMERQKSKKDTSCLMLTEDSEVKKTVSLPTVAVSKGQLEEEPAGRARPMQEVHIKTLEEIKLEKALRVQQSAERSGSSRPQAEAAPVAKRLLRITKRSGTREEKKLELEDNGGAPSQSSVTKMGVSETSDETISDPTKLPVNRCDIVKEKHTQRQQERGASQKEKPALASVRTDEASYYTRVVGKPVLTAVSGVTRHLAKRLPTESSQKGEVETSGIGDSILHVKCAAQTLEKRGKAKPKVNVKPSVVKVVSAPKLAPKRKAVEVHSAVIAAVKPLSSSSVLQESPAKKAAVAVGPLLSEDKSVTMSETEKPKDSSALSSAQASSEPLLPEGSGPSSSQMATKPRRLSSASTGKPPLSVEDDFEKLIWEISGGKLEAEIDLDPGKDEDDLLLELSEMIDS", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**********:*******************:***************************************** *************.************ ********* *****:*** ************.********************************************:***:****.:.******:*.***...:* *:.*****************************:**:* :*:* ******************:** *****************:..***.*************************:*** ::***.****************.************* ** ::**.**::*** :****************** *********:*: *. ***:**** **.:..*:** ** ***:::.***********************:* * ** .* **:* *:********:* :*** :*::.. . ****: . . . :.: * * **: *:**: ::*** *:**** **..*:.:* * ** *:*. *******.*:****:*****:**** **********:*:*****************************:***********:*:*****************.********* **:*******:.*:*:*:** .*..:*:**:. ** ********: *.********************************************************", "identical_positions": 633, "similar_positions": 108, "identity": "76.08%" }, { "cls_id": "homologset.agr.RGD:1308291", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZFQ7-1", "uniprot_id": "D3ZFQ7_RAT", "id": "D3ZFQ7-1", "name": "", "aln": "MEVRPIGWICGQVVKNFSGRFEGLQKAIMDLIDEFKDDLPTILRLSQSNQKKDSVQKTSKVKMALALAKINRGTLIQGLNRISSSSKSVAKLLQPQLACRLLELRNISHRLLREVNAPRQPLNSIQVRKGSLFEIISFPAKTALTSIMYASYAALIYLAVCVNAVLAKIKNIFQEEESIRQNRE-SKNFRKAFSEPVLSEPMFSEGEIKAKPYRSLPEKPDHLSDQPKPPASMQSNKIQVLHSVFDQSAELNE--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D9R3-1", "uniprot_id": "SPAT9_MOUSE", "id": "Q9D9R3-1", "name": "Spermatogenesis-associated protein 9", "aln": "MEVRPIGWICGQVVKNFSGRLEGLQKAIMDLIDEFKDDLPTILRLSQSSQKTDPVQKTSKVRMALALAKINRGTLIQGLNHISSSSKSVAKLLQPRLAYRLLELRSISHRLLREVNVASQPLHSVQMKRGSLFEIISFPAKTALTSIMYASYAALIYLAVCVNAVLAKIKKIFQEEESIRQNRE-SENFRKAFSEPALRKPMFSESEIKAKPYRSLPEKPDNLLDQPKPPANKQSNKIQVLHSVFDQLAELNE--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BWV2-1", "uniprot_id": "SPAT9_HUMAN", "id": "Q9BWV2-1", "name": "Spermatogenesis-associated protein 9", "aln": "MPIKPVGWICGQVLKNFSGRIEGIQKAIMDLVDEFKDEFPTILRLSQSNQKREPAQKTSKIRMAIALAKINRATLIRGLNSISRSSKSVAKLLHPQLACRLLELRDISGRLLREVNAPRQPLYNIQVRKGSLFEIISFPAKTALTSIIYASYAALIYLAVCVNAVLKKVKNIFQEEESIRQNREESENCRKAFSEPVLSEPMFAEGEIKAKPYRSLPEKPD-ISDYPKLLANKQSNNIQVLHSVFDQSAEMNEQI", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* ::*:*******:******:**:*******:*****::*********.** :..*****::**:*******.***:*** ** *********:*:** ******.** *******.. *** .:*:::******************:****************** *:*:************* *:* *******.* :***:*.*************** : * ** *. ***:********** **:** ", "identical_positions": 194, "similar_positions": 40, "identity": "76.08%" }, { "cls_id": "homologset.agr.RGD:1308292", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BG93-1", "uniprot_id": "NUD15_MOUSE", "id": "Q8BG93-1", "name": "Nucleotide triphosphate diphosphatase NUDT15", "aln": "------------MAANAEPR-RRPGVGVG---------VVVLS---CEHPRCVLLGKRKGSFG----AGSFQLPGGHLEFGETWEECAQRETWEEAGLHLKNVCFASVVNSFVEKENYHYVTILMKGEVDMTHDSEPRNMEPEKNESWEWVPWEEFPPLDQLFWALRCLKEQGYDPFKEDLNHLEGYRGEHLERTTKTP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NV35-1", "uniprot_id": "NUD15_HUMAN", "id": "Q9NV35-1", "name": "Nucleotide triphosphate diphosphatase NUDT15", "aln": "------------MTASAQPRGRRPGVGVG---------VVVTS---CKHPRCVLLGKRKGSVG----AGSFQLPGGHLEFGETWEECAQRETWEEAALHLKNVHFASVVNSFIEKENYHYVTILMKGEVDVTHDSEPKNVEPEKNESWEWVPWEELPPLDQLFWGLRCLKEQGYDPFKEDLNHLVGYKGNHL-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0M5Z8-1", "uniprot_id": "A0ABK0M5Z8_RAT", "id": "A0ABK0M5Z8-1", "name": "Nucleotide triphosphate diphosphatase NUDT15", "aln": "SVRVKRVSAQLSSVCSLWPRCPLGSRQEGPLFQDRAPYVLALPSPGCRWKSFVFLVFCFFVFLFFFFSGAGDQTQGLALPSETWEECAQRETWEEAGLRLKNVRFASVVNTFVEKENYHYVTILMKGEVDVTHESEPRNMEPEKNESWEWVPWEEFPPLDQLFWALRCLKEQGYDPFKEDLNHLEGYRGKHLEKTPKIP", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ... ** . * *:. . *. *:* . :*: : . * .***************.*:**** ******:*:*****************:**:***:*:***************:********.******************* **:*:** ", "identical_positions": 106, "similar_positions": 27, "identity": "53.27%" }, { "cls_id": "homologset.agr.RGD:1308294", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4A265-1", "uniprot_id": "D4A265_RAT", "id": "D4A265-1", "name": "", "aln": "MMLSPDQAADSDHPSSTHSDPESLGGVDTKVLGSVSDLEPVEEVDGDGKGGSRAALYPHPQQLSREEKRRRRRATAKYRSAHATRERIRVEAFNLAFAELRKLLPTLPPDKKLSKIEILRLAICYISYLNHVLDV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q64221-1", "uniprot_id": "HEN2_MOUSE", "id": "Q64221-1", "name": "Helix-loop-helix protein 2", "aln": "MMLSPDQAADSDHPSSTHSDPESLGGADTKVLGSVSDLEPVEEADGDGKGGSRAALYPHPQQLSREEKRRRRRATAKYRSAHATRERIRVEAFNLAFAELRKLLPTLPPDKKLSKIEILRLAICYISYLNHVLDV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q02577-1", "uniprot_id": "HEN2_HUMAN", "id": "Q02577-1", "name": "Helix-loop-helix protein 2", "aln": "MMLSPDQAADSDHPSSAHSDPESLGGTDTKVLGSVSDLEPVEEAEGDGKGGSRAALYPHPQQLSREEKRRRRRATAKYRSAHATRERIRVEAFNLAFAELRKLLPTLPPDKKLSKIEILRLAICYISYLNHVLDV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****************:*********.****************.:******************************************************************************************", "identical_positions": 131, "similar_positions": 4, "identity": "97.04%" }, { "cls_id": "homologset.agr.RGD:1308295", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9W0F8-1", "uniprot_id": "Q9W0F8_DROME", "id": "Q9W0F8-1", "name": "rhomboid protease", "aln": "---------------MLLLSGAPSQGR----RPKNRPLIGTVEEGEMPPSTVLQMPPAPLSSKSGLVLGVCCD-QLMAVQPVQRASGAAATKSN-------------------------------------------------------------SPDWGNHRAKHHEGSAAPFKWIPPFFIILATLLEVLVFLWVG----------------ADPPEDSLLVYRPDQRLQLWRFLSYALLHASWLHLGYNVLTQLLFGVPLELVHGSLRTGVIYMAGVLAGSLGTSVVDSEVFLVGASGGVYALLAAQLASLLLNFGQMR--HGVIQLMAVILF-------------------------------------------------VFCDLGYALYSRELAMHQLQTRPSVSYIAHMTGALAGISVGLLLLRQLDGGLRPRPLRWLALGVWCIFSAFGIAFNLVNTVTAQLLAEEEGQVIRQHLMNDLGMG", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P20350-1", "uniprot_id": "RHOM_DROME", "id": "P20350-1", "name": "Protein rhomboid", "aln": "---------------MENLTQNVNETKVDLGQEKEKEASQEEEHATAAKETIIDIPAACSSSSNSSSYDTDCS-TASSTCCTRQGEHIYMQREA-------------------------------------------------------------IPATPLPESEDIGLLKYVHRQHWPWFILVISIIEIAIFAYDRYTMP-----AQNFGLPVPIPSDSVLVYRPDRRLQVWRFFSYMFLHANWFHLGFNIVIQLFFGIPLEVMHGTARIGVIYMAGVFAGSLGTSVVDSEVFLVGASGGVYALLAAHLANITLNYAHMK--SASTQLGSVVIF-------------------------------------------------VSCDLGYALYTQYFDGSAFAKGPQVSYIAHLTGALAGLTIGFLVLKNFGHREYEQLIWWLALGVYCAFTVFAIVFNLINTVTAQLMEEQ-GEVITQHLLHDLGVS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0ABK0LN46-1", "uniprot_id": "A0ABK0LN46_RAT", "id": "A0ABK0LN46-1", "name": "Rhomboid-related protein 2", "aln": "----------------------------------------------MAAAHEMEMESVNLNMEREGKEELEEE-KMRGDGEGKDFPRGRKVHRI-------------------------------------------------------------VSKWMLPEPVRRTYLERANCLPPPLFIVLISLAELAVFIYYAVWKP-----QKQWITLDTGILESPLTYRPEKREEAWRFISYMLVHAGVQHIVGNLFMQLVLGIPLEMVHKGLRVGLVYLAGVLAGSLASSIFDPLKSLVGASGGVYALMGGYFMNVIVNFREMIPALGIVRLLVIILIALVGSNELMEGELQDQQPAGQQSKARPGQREQNPAHCGDPRLHWASSLLVASDMGFALYRRFFVP---ANGSPVSFAAHIAGGFAGMSVGYTVFSCFDKTLLKDPRFWISIAAYVACLLFAVFFNIFLSPAN----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2AGA4-1", "uniprot_id": "RHBL2_MOUSE", "id": "A2AGA4-1", "name": "Rhomboid-related protein 2", "aln": "----------------------------------------------MAVAHEMEMESVNLNMEREGKEEPEEE-KMKGNGEGKDFPRSRKVHRI-------------------------------------------------------------VSKWMLPEPVRRTYLERANCLPPPLFIILISLAELAVFIYYAVWKP-----QKQWITLDTGILESPLTYCPEKREEAWRFISYMLVHAGVQHIVGNLLMQIVLGIPLEMVHKGLRVGLVYLAGVLAGSLASSIFDPLKSLVGASGGVYALMGGYFMNVIVNFREMIPAFGIVRLLVIILI-------------------------------------------------VASDMGFALYRRFFVP---ANGSPVSFAAHIAGGFAGMSIGYTVFSCFDKTLLKDPRFWIAIAAYVACLLFAVFFNIFLSPAN----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NX52-1", "uniprot_id": "RHBL2_HUMAN", "id": "Q9NX52-1", "name": "Rhomboid-related protein 2", "aln": "----------------------------------------------MAAVHDLEMESMNLNMGREMKEELEEEEKMREDGGGKDRAKSKKVHRI-------------------------------------------------------------VSKWMLPEKSRGTYLERANCFPPPVFIISISLAELAVFIYYAVWKP-----QKQWITLDTGILESPFIYSPEKREEAWRFISYMLVHAGVQHILGNLCMQLVLGIPLEMVHKGLRVGLVYLAGVIAGSLASSIFDPLRYLVGASGGVYALMGGYFMNVLVNFQEMIPAFGIFRLLIIILI-------------------------------------------------IVLDMGFALYRRFFVP---EDGSPVSFAAHIAGGFAGMSIGYTVFSCFDKALLKDPRFWIAIAAYLACVLFAVFFNIFLSPAN----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VYW6-1", "uniprot_id": "Q9VYW6_DROME", "id": "Q9VYW6-1", "name": "", "aln": "MPVKTVNRQQSQTPAQQLQLQQQRDVENGLYPTIPAERRSPPSRPQTLRQDTIDMEEIPLNQTNSQEPEDRRKMHEIFDKHDSDRDGLINTHELKELISDGYCRDIPAYIADQILKRSDQDNDGHLDFEEFYAMSLRHKWMVRNMLTRYCRYVVPPPKPLEGDEPDGAYEKQMSICPPPLTMVLFSIIEIIMFLVDVIHFQDDPNYQDRIGESTSGPAATLFIYNPYKRYEGWRFVSYMFVHVGIMHLMMNLIIQIFLGIALELVHHWWRVGLVYLAGVLAGSMGTSLTSPRIFLAGASGGVYALITAHIATIIMNYSEME--YAIVQLLAFLVF-------------------------------------------------CFTDLGTSVYRHLTDQ-----HDQIGYVAHLSGAVAGLLVGIGVLRNLEVRRWERILWWVAVIVYFALMTTGIIIHVFVPDYFPKQEYN----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q86BL6-1", "uniprot_id": "Q86BL6_DROME", "id": "Q86BL6-1", "name": "", "aln": "---------------------------------------------MSAQVESNGASESNNNCVKDVRLLLLPENSTDSDGNPASVAFSAESHKK--------------------------------------------------------------FIDDLTRTIDVGHVRRKRLWRVPWFILLMSFVQISLHWIASECMQ------------------KVLIFKPEWNVEYWRLLTYMLLHSDYWHLSLNICFQCFIGICLEVEQGHWRLAVVYMVGGVAGSLANAWLQPHLHLMGASAGVYAMLGSHVPHLVLNFSQLSHRFARIASLLILLL---------------------------------------------------SDVGFTTYHFCHNHN---RNPRTSLEAHIGGGVAGILCGFIVYRRLQPANQKAIYF-----------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : * :: :: :: :. . : : * . : **:.:* ::* . *: *: * .:*: **: : * .::*:.* .***:..: .. * ***.****:: . . : :*: .: . .::: *:* : * . **: *..**: * : : ", "identical_positions": 36, "similar_positions": 65, "identity": "7.36%" }, { "cls_id": "homologset.agr.RGD:1308296", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K4X6-1", "uniprot_id": "A0A0G2K4X6_RAT", "id": "A0A0G2K4X6-1", "name": "", "aln": "MRRSPPGQPEVNEDLSLDLPSLPLLLSPHFYRNNSDQDEVETEAELSRRLENRLVLLFFGAGACPQCQAFAPVLKDFFVRLTDEFYVLRAAQLALVYVSQDPTEEQQDLFLRDMPEKWLFLPFHDDLRRDLGRQFSVRQLPAVVVLKPGGDVLTSDATDEIQRLGPACFANWQEAAELLDRSFLQPEDLDEPARRSITEPLRRRKYRVDRDAGRGRGRNECDSRNPQGGAGAGTELW-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VC33-1", "uniprot_id": "NXNL1_MOUSE", "id": "Q8VC33-1", "name": "Nucleoredoxin-like protein 1", "aln": "--------------------MASLFSGRILIRNNSDQDEVETEAELSRRLENRLVLLFFGAGACPQCQAFAPVLKDFFVRLTDEFYVLRAAQLALVYVSQDPTEEQQDLFLRDMPEKWLFLPFHDELRRDLGRQFSVRQLPAVVVLKPGGDVLTSDATEEIQRLGPACFANWQEAAELLDRSFLQPEDLDEPARRSITEPLRRRKYRVDRDVGRERGRNGRDSGDPQGDAGTRAELW-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96CM4-1", "uniprot_id": "NXNL1_HUMAN", "id": "Q96CM4-1", "name": "Nucleoredoxin-like protein 1", "aln": "--------------------MASLFSGRILIRNNSDQDELDTEAEVSRRLENRLVLLFFGAGACPQCQAFVPILKDFFVRLTDEFYVLRAAQLALVYVSQDSTEEQQDLFLKDMPKKWLFLPFEDDLRRDLGRQFSVERLPAVVVLKPDGDVLTRDGADEIQRLGTACFANWQEAAEVLDRNFQLPEDLEDQEPRSLTECLRRHKYRVEK-AARG-GRDPGGGGGEEGGAGG---LF-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A5PMF7-1", "uniprot_id": "NXNL1_DANRE", "id": "A5PMF7-1", "name": "Nucleoredoxin-like protein 1", "aln": "--------------------MVDLFLGKVLVKNNKDRDELDTEREIILRLQNRILMLFFGSGDSEKCQDFAPTLKDFYKKLTDEFYVERSAQLVLLYISLDSSEEQQEKFLKELPKRCLFLPYEDPYRQELGVMFEVRDLPRVVVLRPDCSVLSPNAVSEICTLGTDCFRNWQEGAELIDRNFMMNEEFDEGKMRSMTDPIRRIKYKVEDEKKKKKKRDDDDDDDDGGGGGG---PWG", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: . : :**.*:**::** *: **:**:::****:* . :** *.* ****: :******* *:***.*:*:* *.:****: **:::*:: ****:.* *::** *.*. ** ****:*. .**: :...** **. ** ****.**::**.* *:::: **:*: :** **:*: : *: .. . *..* : ", "identical_positions": 94, "similar_positions": 67, "identity": "39.5%" }, { "cls_id": "homologset.agr.RGD:1308297", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZRC3-1", "uniprot_id": "D3ZRC3_RAT", "id": "D3ZRC3-1", "name": "RNA-binding protein 26", "aln": "MVSKMIIENFEALKSWLSKTLEPICDADPSALAKYVLALVKKDKSEKELKALCIDQLDVFLQKETQIFVEKLFDAVNTKSYLPPPEQPSSGSLKVDFLQHQEKDIKKEE-LTKEEEREKKFSRRLNHSPPQSSSRYRDNRSRDERKKDDRSRKRD----------------YDRNPPRRDSYRDRYNRRRGRSRSYSRSRSRS------------------------WSKERLRDRDRDR----------SRTRSRSRTRSRERDLVKPKYDLDRTDPLENN----YTPVSSVSNISSGHYPVPTLS---------------------STITVIAPTHHGNNTTESWSEFHEDQVDHNSYVRPP---------MPKKRCRDYDEKGFCMRGDMCPFDHGSDPVVVEDVN-LPGMLPFPAQP-PVVEGPPPPGLPPPPPILTPPPVNLRPPVPPPGPLPPSLPPVTDDISYSLVLTGPPPPLPPLQPSGMDAPPNSATSSVPTVVTTGIHHQPPPAPPSLFTA-----DTYDTDGYNPEAPSITNTSRPMYRHRVHAQRPNLIGLTSGDMDLPPREKPPNKSSMRIVVDSESRKRTIGSGEPGVPTKKTWFDKPNFNRTNSPGFQKKVQFGNENTKLELRKVPPELNNISKLNEHFSRFGTLVNLQVAYNGDPEGALIQFATYDEAKKAISSTEAVLNNRFIKVYWHREGATHQLQTTSPKVIQPLVQQPILPVVKQSVKERLGPVPSGTVEPAEAQSATSELPQNVTKLSVKDRLGFVSKPSVSATEKVLSTSTG-LTKTVYNPAALKAAQKTLLVSTPAVDNNEAQKKKQEALKLQQDVRKRKQEILEKHIETQKMLISKLEKNKTMKSEDKAEIMKTLEILTKNITKLKDEVKSTS----------PGRCLPKSIKTKTQMQKELLDTELDLYKKMQAGEEVTELRRKYTELQLEAAKRGILSSGRGRGIHTRGRGAAHGRGRG-RGRGRGVPGHAVVDHRPRALEISAFTESDREDLLPHFAQYGEIEDCQIDDSSLHAIITFKTRAEAEAAAVHGARFKGQDLKLAWNKPVANMSAVETEEAEP------------DEEEFQEESLVDDSLLQ---------DDDEEEEDNESRSWRR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6NZN0-1", "uniprot_id": "RBM26_MOUSE", "id": "Q6NZN0-1", "name": "RNA-binding protein 26", "aln": "MVSKMIIENFEALKSWLSKTLEPICDADPSALAKYVLALVKKDKSEKELKALCIDQLDVFLQKETQIFVEKLFDAVNTKSYLPPPEQPSSGSLKVDFLQHQEKDIKKEE-LTKEEEREKKFSRRLNHSPPQSSSRYRDNRSRDERKKDDRSRKRD----------------YDRNPPRRDSYRDRYNRRRGRSRSYSRSRSRS------------------------WSKERLRDRDRDR----------SRTRSRSRTRSRERDLVKPKYDLDRTDPLENN----YTPVSSVSNISSGHYPVPTLS---------------------STITVIAPTHHGNNTTESWSEFHEDQVDHNSYVRPP---------MPKKRCRDYDEKGFCMRGDMCPFDHGSDPVVVEDVN-LPGMLPFPAQP-PVVEGPPPPGLPPPPPILTPPPVNLRPPVPPPGPLPPSLPPVT----------GPPPPLPPLQPSGMDAPPNSATSSVPTVVTTGIHHQPPPAPPSLFTAVFVLPDTYDTDGYNPEAPSITNTSRPMYRHRVHAQRPNLIGLTSGDMDLPPREKPPNKSSMRIVVDSESRKRTIGSGEPGVSTKKTWFDKPNFNRTNSPGFQKKVQFGNENTKLELRKVPPELNNISKLNEHFSRFGTLVNLQVAYNGDPEGALIQFATYEEAKKAISSTEAVLNNRFIKVYWHREGTTQQLQTTSPKVIQPLVQQPILPVVKQSVKERLGPVPSATTEPAEAQSATSELPQNVTKLSVKDRLGFVSKPSVSATEKVLSTSTG-LTKTVYNPAALKAAQKTLSVSTPAVDNNEAQKKKQEALKLQQDVRKRKQEILEKHIETQKMLISKLEKNKTMKSEDKAEIMKTLEILTKNITKLKDEVKSTS----------PGRCLPKSIKTKTQMQKELLDTELDLYKKMQAGEEVTELRRKYTELQLEAAKRGILSSGRGRGIHTRGRGTAHGRGRG-RGRGRGVPGHAVVDHRPRALEISAFTESDREDLLPHFAQYGEIEDCQIDDASLHAIITFKTRAEAEAAAIHGARFKGQDLKLAWNKPIANMSAVDTEEAEP------------DEEEFQEESLVDDSLLQ---------DDDEEEEDNESRSWRR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5T8P6-1", "uniprot_id": "RBM26_HUMAN", "id": "Q5T8P6-1", "name": "RNA-binding protein 26", "aln": "MVSKMIIENFEALKSWLSKTLEPICDADPSALAKYVLALVKKDKSEKELKALCIDQLDVFLQKETQIFVEKLFDAVNTKSYLPPPEQPSSGSLKVEFFPHQEKDIKKEE-ITKEEEREKKFSRRLNHSPPQSSSRYRENRSRDERKKDDRSRKRD----------------YDRNPPRRDSYRDRYNRRRGRSRSYSRSRSRS------------------------WSKERLRERDRDR----------SRTRSRSRTRSRERDLVKPKYDLDRTDPLENN----YTPVSSVPSISSGHYPVPTLS---------------------STITVIAPTHHGNNTTESWSEFHEDQVDHNSYVRPP---------MPKKRCRDYDEKGFCMRGDMCPFDHGSDPVVVEDVN-LPGMLPFPAQP-PVVEGPPPPGLPPPPPILTPPPVNLRPPVPPPGPLPPSLPPVT----------GPPPPLPPLQPSGMDAPPNSATSSVPTVVTTGIHHQPPPAPPSLFTA-----DTYDTDGYNPEAPSITNTSRPMYRHRVHAQRPNLIGLTSGDMDLPPREKPPNKSSMRIVVDSESRKRTIGSGEPGVPTKKTWFDKPNFNRTNSPGFQKKVQFGNENTKLELRKVPPELNNISKLNEHFSRFGTLVNLQVAYNGDPEGALIQFATYEEAKKAISSTEAVLNNRFIKVYWHREGSTQQLQTTSPKVMQPLVQQPILPVVKQSVKERLGPVPSSTIEPAEAQSASSDLPQNVTKLSVKDRLGFVSKPSVSATEKVLSTSTG-LTKTVYNPAALKAAQKTLLVSTSAVDNNEAQKKKQEALKLQQDVRKRKQEILEKHIETQKMLISKLEKNKTMKSEDKAEIMKTLEVLTKNITKLKDEVKAAS----------PGRCLPKSIKTKTQMQKELLDTELDLYKKMQAGEEVTELRRKYTELQLEAAKRGILSSGRGRGIHSRGRGAVHGRGRG-RGRGRGVPGHAVVDHRPRALEISAFTESDREDLLPHFAQYGEIEDCQIDDSSLHAVITFKTRAEAEAAAVHGARFKGQDLKLAWNKPVTNISAVETEEVEP------------DEEEFQEESLVDDSLLQ---------DDDEEEEDNESRSWRR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B7L9-1", "uniprot_id": "A0ACD6B7L9_DANRE", "id": "A0ACD6B7L9-1", "name": "", "aln": "----MIIENLEALKTWLSKTLEPICDADPSALAKYVVALVKKDKSEKELKALCIDQLDVFLQKETQTFVDKLFEAVNAKSYLPQPEQPTPASRPETHQRTEKDEAKREEPPSRDEDREKKFSRRINHSPPSSSRYSRDSRRVDDRKKDDRSRKRE----------------YDRNPPRRDSYRERYNRRRERSRSYSRSRSRS------------------------WSKDRTRDRDRERDRDRDRSRSRSRTRSRSRSRSRERDSGKPKYEHSRPERPEGATTDGYTAAPLPPVNSSAHFPVPTLS---------------------STITVIAPTHHGNNTTESWSEFPQD---HTPFGRGG---------PPRKRCRDYDEKGFCMRGDMCPFDHGSDPVVVEDVN-LPSILPFQPPPLPGVDGPPPPGLPPPHALLTPP-VNLRPPVPPPGTMPPSLPPVA----------GPPPPLPALQPSGMDGPPNSITSSVPTIVTSGIRPPMTQPPPPLFTS-----DPFEPDVYNPEAPSMT--SRPMYRHRVNAQRPNLIGLTMAEMDLPPREKMSNSNNARIVLESDSRKRGAGLHDLAIPPKKPWFDKPNFSKPNHHGFHRKVPFPLANTKLAIGQIPPELNNISKLNQHFSKFGTIVNLQVAYNNDPEGALIQFATPEEARRAIQSTEAVLNNRFIRVHWHREDTVEHMHPKPHPSVQP-AQEPAVTALKQSVKDRLGPLPTPHPEPTPAPSGP---PQNTLKASVKERLGFSKPPGLGT--KVLSTSTG-LTKTVYNPAALKAGQKGAPFS-ASVSAEDALKRKQEAMKLQQDVRKKKQEILEKHIQTQKLLISRLEKNKSMKAEDKAQIMQTLTSLTNSITKLQEEIKGLS----------SANALRTTVKSKAQAQKELLDTELDLYKKMQAGEDTAELKIKYTQLQLEAAKRGLLTPGRGRGAHSRGRGALRSRGRGIRGRGRGAPTHAVVDHRPRALEISGFSEADRVDLLPHFAQYGEIEDCQMEDSSLSAIITYKTRAEAEQAAIHGVRLNNQELRLAWHKPTASLNTTDPDEAEA------------EDEEFPEDSLVDDSLLQ---------DDDEEEEDNESRSWRR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VIV2-1", "uniprot_id": "SWM_DROME", "id": "Q9VIV2-1", "name": "Zinc finger protein swm", "aln": "----MILENSDKLKDWLSVVLEPLCDADSSALARYVIALLKKDKSDKDLKRIMIEQLDVFLSEETTRFVERLFDAIASEEYLTVPAAPLITASSASTAELTVDQELALVIDGPQDDIEAVLVADSPPPPPKDNVIKPDSNQVKLEQASQDAREAEALAFISQEAGIAMHVPTDAKPAFDHKTKDSHNQQSASNYQHHHVRSASPPGRSSGVSGSGGGGPGGAGLAAGYADKENQPRDSRR------RRASLRSRSRSRSRSNERAFRRSRSRDRRVNEREKTQRQFRNKSPPGSQTDNRHHGRRNFDRRRIGGNADDRPRFGNNKSRRSHSRSMSPERNARRNQNSPDRVQTAQANLIPAPVAPPAPVEHPASHPRQRCRDFDEKGYCVRGETCPWDHGVNPVVFEGINNTSLMMSMREYNPDAPEIWARSGGPPPGAGQGPVPPPTQPGQTTINPFSGNVRPTT--------------LMSGSGPSPMGVPNPADYARNPGAPPQAAMMPFPFNPTAVTTP----------------------------LQRQLIPIPVVDGAPTGGVAEVGKRRFELEDTVAIADVPTKRKVPIN---------------------SRLGPRVNPNMQQHNSSLELRKVPRGLNTIAHLNNHFAKFGKIVNIQVSYEGDPEAAIVTFSTHAEANVAYRSTEAVLNNRFIKVFWHNDSSGADVGQMN--QMGGGGGGGGRKNASQYHLHNVPAVPTPNADGAKISNANPLTEAGAGNIGTPATEQANTAAPASMRLKLNTTTAGGSAGGAAGAGAPGSGRPLNPAANAASIRKKQEEQQKAVHQLANGLRKRKQELLQSYMKQMKTALELVERMDQQDPQ-RAPTLQTIKVLQMTIDKLRKEIKADQDQLQAQMQQQQQQQQPPVKKTKEQQKKELLDMELELIAQQQEGNDTTAIQKRLEELQRNLGVG---SAANNKSTHYAPASGAPGGGAG-RKRPNLPEGPTRVDRRPKAIVVTGFAAEEADFVLGHFKNFGEISKHDVDREIPQLILSYATRLNAEQAVLRGKMYKDKRLQISWAPVVTPAPAPMAAPVEKSAAPGDMSVSLENPKQLIQSVSESESLLGSDTLPELRLEDEEEDEESEDRSWRR", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **:** : ** *** .***:****.****:**:**:*****:*:** : *:******.:** **::**:*: ::.**. * * : .: ::: * : .**... :.. . .: .: :*: : * :*. .. :: :*:: . .: : ** * ::... : ** * *:*****:**.** :.: * : * . . . .. *. .:. * ::* ::.... :* ... . *::****:****:*:**: **:*** :***.*.:* . ::.: : . .* *** . * :* .. ..:. .: *.: :. ** *. * : : * . . . *..: *. :* * : * . . : :.: ... *. . .** . . * : : : *:.* : ::* **.*::**:**::**.:**:**:*:.***.*:: *:* **. * ***********:*.**.:.: .: : .* ..: .:*: : : .. .. : .. . . . *: :*::* : . ...* :.: : .: :. :::: . :* :.:**:***:*:.::: * :. :*: . ..: :* ::*: * .* **:.*:*. . . *:* * :***** **:* : * *::.: :: : :** : . :....:. * . . * * * * . : **:**:*: ::.*: : :* ** ::***.. ::: :::: ** :** *.::* :.: *:::* : : . .* : ::: :. .:*** :*:**:*:.*.*****", "identical_positions": 239, "similar_positions": 329, "identity": "20.93%" }, { "cls_id": "homologset.agr.RGD:1308298", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6ABC2-1", "uniprot_id": "A0A8I6ABC2_RAT", "id": "A0A8I6ABC2-1", "name": "Matrix metalloproteinase-25", "aln": "MCLPGSQISPAHLYYLVSAPCR-AGSLTSSIPPGRRESGLFRMPLRSVQAERILRLQALGLPLLVLLLVLLQPVRAQ-NLRAQDVSMGVDWLTRYGYLPPADPVHAQMQSLGKLQDAIKVMQRFAGLPETGQMDPITIATMHKPRCSLPDILGPAGLVRRRRR-----------YTLSGSVWKKRTLTWRISFSLLSIQSFSQ---SSRLSQSVVRTLVSYALDVWAVASGLTFQEVDS-QYQEPDIVIHFSRAYHQDSYPFDGPGGTLAHAFFPGEHPISGDTHFDDEETWTFG--STDGEGTDLFAVAVHEFGHALGLGHSSAPDSIMRPFYQGPVGDPGTYRLSQDDRDGLQQLYG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RVSQTPNDKPTRKPLVPPPQPPVMPPDSPSTPVP---DRCKGNFDAVANIRGEIFFFKGPWFWRLQPSGQLVSPRPAGLHRFWEGLPNDVRVIQAAYARPQDGRIILFSGPQFWVFQ-ERQLQGAARPLVEFGLP-----PGEEVDAVFSWPFNGKTYLIRGQKYWRYDEVAG--SPDPDYPRPLSLWEGAPFAPDDVTISNTGDTYFFKGTHSWRFAKGSVKSESDSPQPIGPTWLDCPAPNSDPQVPSPPKTTPETRSCDCHCELNQTSEQLSSTFLLP-LLPLLAGAIFSC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3U435-1", "uniprot_id": "MMP25_MOUSE", "id": "Q3U435-1", "name": "Matrix metalloproteinase-25", "aln": "MCFPGSQISPARLYYLVSAPWICTGSLTSSRLPRRRESGPLRVPPRSVQAERILRLPAFGLPLLALLLVPLLPVRAQ-NPDAKVVSMGVEWLTRYGYLPPADPVHAQMQSLEKLQDAIKVMQRFAGLPETGQMDPMTIKTMRKPRCSLPDVLGAAGLVRRRRR-----------YSLSGSVWKKRTLTW-------SIRSFSQ---KSQLSPQIVRTLLSYALAVWATESGLTFQEVNS-QYQEPDIIIHFARAYHQDSYPFDGSGGTLAHAFFPGEHPISGDTHFDDEETWTFG--STDDNGIDLFAVAVHEFGHALGLGHSSAPNSIMRPFYQGPVGDPATYRLPQDDRDGLQQLYG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RVSQNPNARPTRKPLVPPPQPPAMPPDSPATPVP---DRCEGNFDAVANIRGEIFLFKGPWFWRLQPSGQLVSPRPAGLHRFWEGLPTHVKVIQAAYARPLDGRIILFSGPQFWVFQ-ERQLEGAARPLVEFGLP-----PGEDVDAVFSWPHNGKTYLIRGQKYWRYDEVAA--RPDPGYPRALSLWDGAPFAPDDVTISNTGDTYFFKGTHFWRFAEGSVKAESDSPQPIGPKWLDCPAPNSDPRVTSPPKTTSKTRSCDCHCELNQASEQLS-PLLLP-LLPLVAGEVFSY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NPA2-1", "uniprot_id": "MMP25_HUMAN", "id": "Q9NPA2-1", "name": "Matrix metalloproteinase-25", "aln": "-----------------------------------------------------MRLRLRLLALLLLLLAP--PARAP-KPSAQDVSLGVDWLTRYGYLPPPHPAQAQLQSPEKLRDAIKVMQRFAGLPETGRMDPGTVATMRKPRCSLPDVLGVAGLVRRRRR-----------YALSGSVWKKRTLTWR-------VRSFPQ---SSQLSQETVRVLMSYALMAWGMESGLTFHEVDSPQGQEPDILIDFARAFHQDSYPFDGLGGTLAHAFFPGEHPISGDTHFDDEETWTFG--SKDGEGTDLFAVAVHEFGHALGLGHSSAPNSIMRPFYQGPVGDPDKYRLSQDDRDGLQQLYG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KAPQTPYDKPTRKPLAPPPQPPASPTHSPSFPIP---DRCEGNFDAIANIRGETFFFKGPWFWRLQPSGQLVSPRPARLHRFWEGLPAQVRVVQAAYARHRDGRILLFSGPQFWVFQ-DRQLEGGARPLTELGLP-----PGEEVDAVFSWPQNGKTYLVRGRQYWRYDEAAA--RPDPGYPRDLSLWEGAPPSPDDVTVSNAGDTYFFKGAHYWRFPKNSIKTEPDAPQPMGPNWLDCPAPSSGPRAPRPPKATPVSETCDCQCELNQAAGRWPAPIPLL-LLPLLVGGVASR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PJH5-1", "uniprot_id": "A0A8M9PJH5_DANRE", "id": "A0A8M9PJH5-1", "name": "", "aln": "---------------------------------------------------MTTALTVTSAALLCVVCAR--PALMP-DQYAR----GVDWLIRYGYLQSPDTLIGGLQTKESIEEAVRKMQRFAGIEETGNLDQKTLEMMGRPRCSLPDTISFEELLKRNRRGKNKVMMKKKRYTLPKMRWDKTDITWS-------MQDFPPPSVSPALNPGLVRLILGNALRVWSENTPLRFHYSPDEPSPQTDITVTFTSGYHEDGYPFDGKGGALAHAFFPGKGDLAGDTHFDAEESWTYG--DWSSD-SDLFTVAVHEFGHALGLFHSSSSDSIMKPYYFSPVGEMNSYSLTAVDRLGIQALYG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KQHNLKPPPSVAAPTTYPTQFSTTYLLHPPYYPPDSADRCQGGYDAVANIRAEIFFFRGQHFWRVDHSGSLLSSTPALIHSFWIGLPPDTARVDAAYER-RDGHIVFFIGNQYWVFRNTMALPGYPRQLSDWGLHTAAGQLAESVEAVFVWPHNGKTYVFSSGLYWRFDEAGGERKMEEGYPKPAAIWG-MPSHPDDIIAFLDGETYFFKDSNYWILQRGGLDLESASPKSIATDWMKC-----DRHVSAPTPEIPRDRNCSCVQNVAAVMRSLSVIIYLTNIICILVVTVF--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8MPP3-1", "uniprot_id": "D2MP_DROME", "id": "Q8MPP3-1", "name": "Matrix metalloproteinase-2", "aln": "--------------------------------------MFSKYVLATLLALFAQSMCIQELSLPPEGSHSTAATRSKKAKTAISEDIMYNYLMQFDYLPKSDLETGALRTEDQLKEAIRSLQSFGNITVTGEIDSATARLIQKPRCGVGDRRSADSFSPDNLYHEIGSNVRVRRFALQGPKWSRTDLTWS----------MVN---RSMPDASKVERMVQTALDVWANHSKLTFREVYS---DQADIQILFARRAHGDGYKFDGPGQVLAHAFYPGEG-RGGDAHFDADETWNFDGESDDSHGTNFLNVALHELGHSLGLAHSAIPDAVMFPWYQ---NNEVAGNLPDDDRYGIQQLYGTKEKTWGPYKPQTTTTTTTTTTMRAMIYRADKPAYWPWNNPSNNPNNDRNRARERQEEERRRQEKERRRQEEERRHQEEERRRQVEERQRQEEERWRQEQERQEEENRRRKIEHKSQWERNPSKERNRPRERQEMERRRQEQERQEQERQEQEDRRRERERDRQLEWERRNRNGAREPVTPTANTTPRPTNKPYPTVHRQHHHHNKPRKPKPDSCMTYYDAISIIRGELFIFRGPYLWRIGTSG-LYNGYPTEIRRHWSALPENLTKVDAVYEN-KQRQIVFFIGREYYVFNSVMLAPGFPKPLASLGLPP----TLTHIDASFVWGHNNRTYMTSGTLYWRIDDYTG--QVELDYPRDMSIWSGVGYNIDAAFQYLDGKTYFFKNLGYWEFNDDRMKVAHARAKLSARRWMQCAR---SANEVDDEQRWTASLVSEGEETGRSGSRELRINHFILSILLLAIANWRS-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .* .. * ::* ::.** .. . ::: .:.:*:: :* *..: **.:* * : :***.: * . : . ::* *.: :** : . . *. :: ** .*. : * *: . :.** : *: * *.* *** * .*****:**: .**:*** :*:*.:. . ... ::: **:**:**:*** **: .:::* *:* .: *. ** *:* *** : .. * * * * :**:: **.* *:*:* :**: ** * . *: :: .* .** . ::*.* . : :*::* * :::**. * .: * . ** ::* * * *.:**: . *** *: . : .**: ::* * *.*****. * : . :. .: . *:.* . . . .. : :: : ", "identical_positions": 127, "similar_positions": 151, "identity": "15.34%" }, { "cls_id": "homologset.agr.RGD:1308299", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Y530-1", "uniprot_id": "OARD1_HUMAN", "id": "Q9Y530-1", "name": "ADP-ribose glycohydrolase OARD1", "aln": "---------------------MASSLNEDPEGSRITYVKGDLFACPKTDSLAHCISEDCRMGAGIAVLFKKKFG------GVQELLNQQKKSGEVAVLKRDGRYIYYLITKKRASHKPTYENLQKSLEAMKSHCLKNGVTDLSMPRIGCGLDRLQWENVSAMIEEVFEATDIKITVYTL----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8R5F3-1", "uniprot_id": "OARD1_MOUSE", "id": "Q8R5F3-1", "name": "ADP-ribose glycohydrolase OARD1", "aln": "---------------------MATRLNEDPEGSRITYVKGDLFACPKTDSLAHCISEDCRMGAGIAVLFKKRFG------GVQELLSQQKKSGEVAVLKRDGRYIYYLITKKRASHKPTYENLQKSLEAMKSHCLKNGVTDLSMPRIGCGLDRLQWENVSAILEEVFESTDIKITVYTL----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZU86-1", "uniprot_id": "A0A8I5ZU86_RAT", "id": "A0A8I5ZU86-1", "name": "", "aln": "---------------------MASRINEDPEGSRITYVKGDLFACPKTDSLAHCISEDCRMGAGIAVLFKKRFG------GVQELLSQRE--FEHRILFHAG---------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8IPU1-1", "uniprot_id": "Q8IPU1_DROME", "id": "Q8IPU1-1", "name": "ADP-ribose glycohydrolase OARD1", "aln": "-----MYSPKLLELRSAFRRAFVVGMSSKPQ-YTLSEVDGDLFSAPKTYSLAHCVGADLAMGAGIAVQFKKVFG------RLDELQAQQAGSGDIAVLKDDQRYIYYLVTKPQSWGKPTYESVQASLEQMREHMRKNNVNKLAIPKIGCGIDGLEWEKVSGVLEE--NNGSFSLI--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A8JNW5-1", "uniprot_id": "A8JNW5_DROME", "id": "A8JNW5-1", "name": "ADP-ribose glycohydrolase OARD1", "aln": "-------------------------MSG----LTYREINGDLFKCQRDYSMCHCVAADLRMGRGIAVKFRNKFG------QLLNLQRQNVQPGGVAVLQDQQRFIYYLITKKSSWGKPTYELLQSSLIAMRKHMISHQVPKLAMPRIGCGLDGLNWPKVKEIICQVFQADSVELVVYNYVAMK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38218-1", "uniprot_id": "POA1_YEAST", "id": "P38218-1", "name": "ADP-ribose 1''-phosphate phosphatase", "aln": "MSNITYVKGNILKPKSYARILIHSCNCNGSWGGGIAYQLALRYPKAEKDYVEVCEKYGSNLLGKCILLPSYENSDLLICCLFTSSFGGSSHGEKQSILNYTKLALDKLKTFREAKDKTRTSEDSIGDYLNGHIKYPIGEYKLEMPQINSGIFGVPWKETERVLEEFSGDMSFTVYQL------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . : * . : : . . . :* ", "identical_positions": 2, "similar_positions": 11, "identity": "1.09%" }, { "cls_id": "homologset.agr.RGD:1308301", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VEJ4-1", "uniprot_id": "NLE1_MOUSE", "id": "Q8VEJ4-1", "name": "Notchless protein homolog 1", "aln": "--------MAAAVVEEAAAGDVQRLLVQFQ--------DEGGQLLGSPFDVPVDITPDKLQLVCNALLAQ-EEPLPLAF-----------YVHDAEIVSSLGKTLESQ-SVETEKIVDIIYQPQAVFRVRAVTRCTSSLEGHSEAVISVAFSP-TGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDGKKLASGCKNGQVLLWDPSTGLQVGRTLTGHSKWITGLSWEPLHMN-PECR-YVASSSKDGSVRVWDTTAGRCERILTGHTQSVTCLRWGGDGLLYSASQDRTIKVWRAHDGVLCR-TLQGHGHWVNTMALSTDYALRTGAFEPAEATVNAQDLQGSLKELKERASSRYNLVR---GQGPERLVSGSDDFTLFLWSPAEDKKPLARMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLATDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIWRR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7FIP9-1", "uniprot_id": "F7FIP9_RAT", "id": "F7FIP9-1", "name": "Notchless protein homolog 1", "aln": "--------MAAAVEDEAAASDVQRLLVQFQ--------DEGGQLLGSPFDVPVDITPDQLQLVCNALLAQ-DEPLPLAF-----------YVHDAEIVSSLGKTLESQ-SVETEKIVDIIYQPQAVFRVRAVTRCTSSLEGHSEAVISVAFSP-TGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDGKKLASGCKNGQILLWDPSTGTQVGRTLTGHSKWITGLSWEPLHMN-PECR-YVASSSKDGSVRVWDTTAGRCERILTGHTQSVTCLRWGGDGLLYSASQDRTIKVWRAHDGVLCR-TLQGHGHWVNTMALSTDYALRTGAFEPAEATVNAQDLQGSLKELKERASSRYNLVR---GQGPERLVSGSDDFTLFLWSPAEDKKPLARMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLTTDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIWRR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NVX2-1", "uniprot_id": "NLE1_HUMAN", "id": "Q9NVX2-1", "name": "Notchless protein homolog 1", "aln": "--------MAAAVPDEAVARDVQRLLVQFQ--------DEGGQLLGSPFDVPVDITPDRLQLVCNALLAQ-EDPLPLAF-----------FVHDAEIVSSLGKTLESQ-AVETEKVLDIIYQPQAIFRVRAVTRCTSSLEGHSEAVISVAFSP-TGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDGRKLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHAN-PECR-YVASSSKDGSVRIWDTTAGRCERILTGHTQSVTCLRWGGDGLLYSASQDRTIKVWRAHDGVLCR-TLQGHGHWVNTMALSTDYALRTGAFEPAEASVNPQDLQGSLQELKERALSRYNLVR---GQGPERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIWRR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QDT3-1", "uniprot_id": "F1QDT3_DANRE", "id": "F1QDT3-1", "name": "Notchless protein homolog 1", "aln": "-----------------MSADVERVLIQLQ--------DEAGEVLGSPFDVPLDISPDKLQLVCNALLQK-EEPVPFLF-----------FVKDAELVSSLGSCIQTL-GLETEQVLPVVYQPQAVFRVRAVARCTSSLEGHTEAVISVAFSP-TGKYLASGSGDTTVRFWDLSTETPHHTSRGHTHWVLSIAWSPDGKKLASGCKNSQIFLWDPVTGKQIGKTLTGHTKWITWLCWEPLHLN-PECR-YLASTSKDCTIRIWDTVLGHYDKILTGHTHSVTCVKWGGDGLLYTSSQDRTIKVWRAKDGVQCR-TLQGHAHWVNTLALSTDYVLRTGAFEPANATINPQDLTGSLEEIKEKALKRYNSVR---GEGHERLVSGSDDFTMFLWNPAEDKKPVARLTGHQALVNEVLFSPDTRLIASASFDKSIKIWDGKTGKYLNSLRGHVGPVYQVAWSADSRLLVSGSSDSTLKVWDIKTGKLNADLPGHADEVFAVDWSPDGQRVASGGKDKCLRIWRK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VPR4-1", "uniprot_id": "NLE_DROME", "id": "Q9VPR4-1", "name": "Protein Notchless", "aln": "---MLAKKQKMQETDTEQEATPHTIQARLV--------SDTGEEAGPPIDLPAGITTQQLGLICNALLKN-EEATPYLF-----------FVGEDEIKKSLEDTLDLA-SVDTENVIDIVYQPQAVFKVRPVTRCTSSMPGHAEAVVSLNFSP-DGAHLASGSGDTTVRLWDLNTETPHFTCTGHKQWVLCVSWAPDGKRLASGCKAGSIIIWDPETGQQKGRPLSGHKKHINCLAWEPYHRD-PECR-KLASASGDGDCRIWDVKLGQCLMNIAGHTNAVTAVRWGGAGLIYTSSKDRTVKMWRAADGILCR-TFSGHAHWVNNIALSTDYVLRTGPFHPVKDRSKS-HLSLSTEELQESALKRYQAVC---PDEVESLVSCSDDNTLYLWRNNQNK-CVERMTGHQNVVNDVKYSPDVKLIASASFDKSVRLWRASDGQYMATFRGHVQAVYTVAWSADSRLIVSGSKDSTLKVWSVQTKKLAQELPGHADEVFGVDWAPDGSRVASGGKDKVIKLWAY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25382-1", "uniprot_id": "NLE1_YEAST", "id": "P25382-1", "name": "Ribosome assembly protein 4", "aln": "MSTLIPPPSKKQKKEAQLPREVAIIPKDLPNVSIKFQALDTGDNVGGALRVPGAISEKQLEELLNQLNGTSDDPVPYTFSCTIQGKKASDPVKTIDITDNLYSSLIKPGYNSTEDQITLLYTPRAVFKVKPVTRSSSAIAGHGSTILCSAFAPHTSSRMVTGAGDNTARIWDCDTQTPMHTLKGHYNWVLCVSWSPDGEVIATGSMDNTIRLWDPKSGQCLGDALRGHSKWITSLSWEPIHLVKPGSKPRLASSSKDGTIKIWDTVSRVCQYTMSGHTNSVSCVKWGGQGLLYSGSHDRTVRVWDINSQGRCINILKSHAHWVNHLSLSTDYALRIGAFDHTG------KKPSTPEEAQKKALENYEKICKKNGNSEEMMVTASDDYTMFLWNPLKSTKPIARMTGHQKLVNHVAFSPDGRYIVSASFDNSIKLWDGRDGKFISTFRGHVASVYQVAWSSDCRLLVSCSKDTTLKVWDVRTRKLSVDLPGHKDEVYTVDWSVDGKRVCSGGKDKMVRLWTH", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : *: * .: :* *: .:* : * * ::. * * * :: ..* . : .**. : ::* *:*:*:*:.*:*.:*:: ** .:::. *:* . :.:*:**.*.*:** .*:** .* ** :***.::*:***. :*:*. . : :*** :* * .* **.* *. *.*** * * .: :**:* * ::**. ::***::*:.::*** **:*:.*:***:::* . * :..*.**** ::*****.** *.*. . . : :* :: * ..*: : : * :*: *** *::** :.. : *:**** ::*.* :*** : :.*****:*:::* . *::: ::**** .** :***:*.**:** *.*:*****.::: ** :**** ***: ***: **.**.****** :::* ", "identical_positions": 172, "similar_positions": 157, "identity": "33.01%" }, { "cls_id": "homologset.agr.RGD:1308302", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U4F0-1", "uniprot_id": "RRP8_RAT", "id": "Q5U4F0-1", "name": "Ribosomal RNA-processing protein 8", "aln": "MFEEPEWVEAAPAIVGLRPVTTQVQAATAPPVKGRKRRHLLATLRALEAASLSQQCPSLPGSDSEEE-----EEVGRKKRHFQR---SSLANVSKEVGK-------KRKGKCQKQAPFISDSEGKEVER--TCHRQAPPLGGISAGEEKGKRKCQEYSYLHPTQSLNS--VDQTVHNSRTSTATLDPPKSSRESASPNSSHTLSRKQWRNR----QKNKR-------------------------------------------RHKNKFRPLETQDQVPLKAS----IEETEVPPAPKSDSQETR-----------AGALRARMTQRLDGARFRYLNEQLYSGPSSAAQCLFQEDPEAFLLYHRGFQRQVKKWPLHPVDRIAKDLR----------------QKPASLVVADFGCGDCRLASSVR-----------------NPVHCFDLAALDPRVTVCDMAQVPLEDESVDVAVFCLSLMGTNIRDFLEEANRVLKPGGLLKVAEVSSRFEDIR--TFLGAVTKLGFKVIYKDLTNSHFFLFDFEKTGPPRVGPKAQLSG--------------------------LKLQPCLYKHR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DB85-1", "uniprot_id": "RRP8_MOUSE", "id": "Q9DB85-1", "name": "Ribosomal RNA-processing protein 8", "aln": "MFEEPEWVEAAPAIVGLGAATAQVRPATAPPVKGRKRRHLLATLRALEAASLSQQTPSLPGSDSEEE-----EEVGRKKRHLQR---PSLASVSKEVGK-------KRKGKCQKQAPSISDSEGKEIRR--KCHRQAPPLGGVSAGEEKGKRKCQEYSSLHLTQPLDS--VDQTVHNSRTSTATIDPSKPSPESMSPNSSHTLSRKQWRNR----QKNKR-------------------------------------------RHKNKFRPLQTPEQAPPKAS----IEETEVPPVPKSDSQESR-----------AGALRARMTQRLDGARFRYLNEQLYSGPSSAARRLFQEDPEAFLLYHRGFQRQVKKWPLHPVDRIAKDLR----------------QKPASLVVADFGCGDCRLASSVR-----------------NPVHCFDLASLDPRVTVCDMAQVPLEDESVDVAVFCLSLMGTNIRDFLEEANRVLKTGGLLKVAEVSSRFEDIR--TFLGAVTKLGFKIIYKDLTNSHFFLFDFEKTGPPRVGPKAQLSG--------------------------LKLQPCLYKRR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43159-1", "uniprot_id": "RRP8_HUMAN", "id": "O43159-1", "name": "Ribosomal RNA-processing protein 8", "aln": "MFEEPEWAEAAPVAAGLGPVISRPPPAASSQNKGSKRRQLLATLRALEAASLSQHPPSLCISDSEEE-----EEE-RKKKCPKK---ASFASASAEVGK-------KGKKKCQKQGPPCSDSE-EEVERKKKCHKQA-LVGSDSAEDEKRKRKCQKHAPINSAQHLDN--VDQTGPKAWKGSTTNDPPKQSPGSTSPKPPHTLSRKQWRNR----QKNKR-------------------------------------------RCKNKFQPPQVPDQAPAEAP----TEKTEVSPVPRTDSHEAR-----------AGALRARMAQRLDGARFRYLNEQLYSGPSSAAQRLFQEDPEAFLLYHRGFQSQVKKWPLQPVDRIARDLR----------------QRPASLVVADFGCGDCRLASSIR-----------------NPVHCFDLASLDPRVTVCDMAQVPLEDESVDVAVFCLSLMGTNIRDFLEEANRVLKPGGLLKVAEVSSRFEDVR--TFLRAVTKLGFKIVSKDLTNSHFFLFDFQKTGPPLVGPKAQLSG--------------------------LQLQPCLYKRR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q5G5-1", "uniprot_id": "A0A8M9Q5G5_DANRE", "id": "A0A8M9Q5G5-1", "name": "Ribosomal RNA-processing protein 8", "aln": "MFAEEDWTDS-PSLNGS-PLSAKLSPASGKK-KAVGKQSLLRTLQTLGSVPDWEVGKAVEEDSDEEKDASAAVKKPKKKRCKKRKRKSNADNEEKQMGEEDSEAPVKKKKTTTKPVKKTKRSVVSEEPKKDDNAVRAQLEKNESQTEKKLSRQQWKNKMKNKRKSKNKYLQKQTSDDTSPKKETLVQTQQIKEFKNPLKPDRTSKKTSKKINKIIEKNASSIGDNAGTCTDSKTDKTIFTETIKVDDSLNNSYNTSQEIGETDKHAKKTKKLQAEKLRRILKSKSSRTDSDKVTETPKDAAVDLKGVEDQTAPLDPSTALRLKMEKQLEAARFRFINEQLYTSTSAAAKRMFQQDPDAITIYHKGYTTQVQHWPTNPVDSIISYIC----------------QKPASLVVADFGCGDCKIARSVK-----------------NKVHSFDLAPVCELATACDMAKVPLGDSTVNIAVFCLSLMGTNLGDFLAEANRVLVMGGVLKIAEVASRFENVH--SFVRALSNMGFKIVNKDTENSHFFSFEFIKTR--KAPENAKKFG--------------------------LQLKPCLYKKR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7K2B0-1", "uniprot_id": "RRP8_DROME", "id": "Q7K2B0-1", "name": "Ribosomal RNA-processing protein 8", "aln": "-------------------------------------------MKPFEVPPWEEGADIIEFEPVNPSGNGVAAKKKPKK---------------------------KKPKKKKAAVPNENLNVNKAAEKFTYRQGRGPLAPPQDSSDDDYEDVEDGIRAMHKVKSGRIEKQRPPTQATKGGKKELKLKPELAQAALEAMEATSSTTPAANS------------------------------------------------------------------------------------------------------------LASKLQSELLGGRFRYINEQLYSTTSRKAEALFRKDSSAFEAYHAGYRQQVEKWPINPLNRIIKTIK----------------KIPKTAIIGDFGCGEGKLAQSVP-----------------NKVYSMDLVAARSDIIACNITDTPLQARTLDVAVYCLSLMGTDLNEFFLEANRVLKLHGTVYIAEIQSRFQDVR--EFVRCLNACGFDLNKKDVAVNYFYFFQFKKMR--HVPKNTKMKA--------------------------FSLKPCLYRKR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38961-1", "uniprot_id": "RRP8_YEAST", "id": "P38961-1", "name": "25S rRNA (adenine(645)-N(1))-methyltransferase", "aln": "-------------------------------------------MALFNVEGWSIKTKTVAFDNKTNKSS-------------------------------------KDKKKNNRKNGKLTREQKLKEETEAELKEQVEDIPSEGSVAKDIPKKNQEKSDQNETSKKRKHDEEAPLMQVKENIEKPTKKQLTP-------------------------------------------------------------------------------------------------------------------------------LQQKMMAKLTGSRFRWINEQLYTISSDEALKLIKEQPQLFDEYHDGFRSQVQAWPENPVDVFVDQIRYRCMKPVNAPGGLPGLKDSKEIVIADMGCGEAQLALEINNFFKNYNKKAKKYLKRRHKVHSFDLKKANERITVADIRNVPLPDESCTIVVFCLALMGTNFLDFIKEAYRILAPRGELWIAEIKSRFSDGKGNEFVDALKLMGFFHKKTFDENKMFTRFEFFKPPAEIIEERRQKLERRQKFIEVETEKEELEKKRRKIAEGKWLLKPCIYKRR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : . . * . . . : . .. : . . * :: .* ..***::*****: .* * :::::.. : ** *: **: ** :*:: : : : . ::.*:***: ::* .: : *:.:** ..:: ..** : :.*:**:****:: :*: ** *:* * : :**: ***.: : *: .:. ** . . * *:* * . : *:**:*::*", "identical_positions": 61, "similar_positions": 89, "identity": "10.18%" }, { "cls_id": "homologset.agr.RGD:1308303", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8J8XD13-1", "uniprot_id": "A0A8J8XD13_RAT", "id": "A0A8J8XD13-1", "name": "V-type proton ATPase 21 kDa proteolipid subunit c''", "aln": "MTG--------LELLYLGIFVAFWACMIVVGICYT--IFDLGFRFDVAWFLTETSPFMWSNLGIGLAISLSVVGAAWGIYITGSSIIGGGVKAPRIKTKNLVSIIFCEAVAIYGIIMAIVISNMAEPFS---ATDPKAIGHRNYHAGYSMFGAGLTVGLSNLFCGVCVGIVGSGAALADAQNPSLFVKILIVEIFGSAIGLFGVIVAILQTSRVKMGD--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91V37-1", "uniprot_id": "VATO_MOUSE", "id": "Q91V37-1", "name": "V-type proton ATPase 21 kDa proteolipid subunit c''", "aln": "MTG--------LELLYLGIFVAFWACMVVVGICYT--IFDLGFRFDVAWFLTETSPFMWSNLGIGLAISLSVVGAAWGIYITGSSIIGGGVKAPRIKTKNLVSIIFCEAVAIYGIIMAIVISNMAEPFS---ATEPKAIGHRNYHAGYSMFGAGLTVGLSNLFCGVCVGIVGSGAALADAQNPSLFVKILIVEIFGSAIGLFGVIVAILQTSRVKMGD--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99437-1", "uniprot_id": "VATO_HUMAN", "id": "Q99437-1", "name": "V-type proton ATPase 21 kDa proteolipid subunit c''", "aln": "MTG--------LALLYSGVFVAFWACALAVGVCYT--IFDLGFRFDVAWFLTETSPFMWSNLGIGLAISLSVVGAAWGIYITGSSIIGGGVKAPRIKTKNLVSIIFCEAVAIYGIIMAIVISNMAEPFS---ATDPKAIGHRNYHAGYSMFGAGLTVGLSNLFCGVCVGIVGSGAALADAQNPSLFVKILIVEIFGSAIGLFGVIVAILQTSRVKMGD--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VFE3-1", "uniprot_id": "Q9VFE3_DROME", "id": "Q9VFE3-1", "name": "V-type proton ATPase 16 kDa proteolipid subunit c", "aln": "MAAQI------RTVVSQTFLWLFLAVATILTLYFV--MTGKGERVSVGWFLASSNPYMWACLGIGLSVSLSVVGAALGIHTTGTSIVGGGVKAPRIKTKNLISVIFCEAVAIYGLITAIVLSGQLEQFSMETALSQAAIQNTNWFSGYLIFGAGLAVGLVNLFCGIAVGIVGSGAALSDAANAALFVKILIVEIFGSAIGLFGLIVGIYMTSKSKMGDKE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VFE5-1", "uniprot_id": "Q9VFE5_DROME", "id": "Q9VFE5-1", "name": "V-type proton ATPase 16 kDa proteolipid subunit c", "aln": "MISKM------SFGLFFMLFVLGAASLGAVGIIFANVMVNMGERMGLGWFLYTSNPFLWSGMGIFLACALSVLGAASGIYMIGCSVAGGGVRSPRIKTKNLISVIFCEAVAIYGLITAILLSGNVNKFSSVRLITDSTVMATNMFTGFATFGAGLCVGMVNVACGIAVGIVGSGAALADAANSALFVKILIVEIFGSAIGLFGLIVAIYMTSKAETIN--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P23968-1", "uniprot_id": "VATO_YEAST", "id": "P23968-1", "name": "V-type proton ATPase subunit c''", "aln": "MNKESKDDDMSLGKFSFSHFLYYLVLIVVIVYGLYKLFTGHGSDINFGKFLLRTSPYMWANLGIALCVGLSVVGAAWGIFITGSSMIGAGVRAPRITTKNLISIIFCEVVAIYGLIIAIVFSSKLTVAT-----AENMYSKSNLYTGYSLFWAGITVGASNLICGIAVGITGATAAISDAADSALFVKILVIEIFGSILGLLGLIVGLLMAGKASEFQ--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . : . : : . * .... ** :.*::*: :** *. .***:*** **. * *: *.**::***.****:*:****.*****:* **::*. : * .:*: * **: ** *: **:.***.*: **::** :.:******::***** :**:*:**.: :.: . : ", "identical_positions": 77, "similar_positions": 59, "identity": "35.0%" }, { "cls_id": "homologset.agr.RGD:1308305", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D3P1-1", "uniprot_id": "TCHL1_MOUSE", "id": "Q9D3P1-1", "name": "Trichohyalin-like protein 1", "aln": "MPRLLRGVFCVVEIFHKYAIEDGGNQATLTRTELRQLLEGEIGDFLQPHVFHAVERKLNLLNFDRDGTISFEEFVLAIFSLLNPSYFDIS-LLNSEPRLMSKSEK--IDAVDLGAIGGNIQQVVGVGPTQERLIFPSEMASSGQPSNEEGEVGDEPMVSPCEDIKTHSLPRNVSEPNDPENQQPK--EDAQEVAQNVPATEYDGVQFKRNTVVEVPKQSTSPT------QEIPRERSKPSRRLSDTKISDHM-----------------IQRPTEDE------EHTSTTQDPFLQKRDKATGSENTDLSVVAATRKSSQTQEIFEPMDDTKLSEAQETGKDAGRIPPETN-LEEPKADAKVAESHGLPAQEREHNTRDQSVQSRSRNVSETSSRGEQEGE-----------WKEHERITLSPTADAETQDEKCQEFPGSWRENDAKKDSAAKDPSSEEGNQNLPEIKEDSVSGKEARHSEEDTVYAFEINKNSPAAEETLETRERSQELAPLEKQSQRKKHRATRIQDKPVRKEDHNEGEDSELSLTQSDEGFCEIPNSLAPEVGKSSSEIAEPHVPEDSQSQIDHHGDAKQESHTNNPDPQKQGAPGESSREQEAVVLSIQ-EDGQLPEGQEQSARDGLHDGLSSRTKGGPGAAVEPSEGEEVQEATAGRENRKALEAESLEAQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZBF6-1", "uniprot_id": "D3ZBF6_RAT", "id": "D3ZBF6-1", "name": "", "aln": "MSRLLRGIFCVIEIFHKYASEDGNKEAMLTHRELRQLLEGEIGDFLQPHVFHAVERKLNLLHFDRDGTISFEEFLLAIFSLLNPPYFDIS-LLNSEPRLMSKSEK--TDAVDLGAITGSTQRVVGVGPTQERLIFPPEMSLSDQSRKEEGEAGDELMVSPWEDVKTHGLPRNVSEPNDPEKHQPK--EDAQEIAQTVPAAEYDVVQYQRNTAVEVSKQSAGPT------QEIPRQGNKTSRRQSDTKISDYV-----------------IQRPTDYE------EHASATQDPILQKEDKVAGSAHTDLPVVAATGKSSQTQEVLEPTDDTRLSETQGTGKDAGRMPPETTHLEEPKADASASGSHSLPVQEREH------VQSRSRNVSETSSRGDLEEE-----------CKEHERKTRSLAPEAETPDEKCQEFPGSQRENDVERGTAALDPSSGEGNQNLPEVKEESISEKKARHSEKDTVDTFAINKTSPAIEETPETRERSQELAPLEEQSQGKQHRAAKTHDESVRKEDHSEGEDPELSPTQSDEGFCETPNSLAPEVGKSSSEIAETRVPGESQRQVEHHGDAKQESHINNPDSQKQGVPGESNREQEEVVLSIQ-EDGQLPEEQEE-------------------------EREE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5QJ38-1", "uniprot_id": "TCHL1_HUMAN", "id": "Q5QJ38-1", "name": "Trichohyalin-like protein 1", "aln": "MPQLLRNVLCVIETFHKYASED-SNGATLTGRELKQLIQGEFGDFFQPCVLHAVEKNSNLLNIDSNGIISFDEFVLAIFNLLNLCYLDIKSLLSSELRQVTKPEKEKLDDVDVQATTGDGQWTVGTSPTQEKRMLPSGMASSSQLIPEESGAVGNNRVDPWREAKTHNFPGEASEHNDPKNKHLEGDEQSQEVAQDIQTTEDNEGQLKTNKPMAGSKKTSSPTERKGQDKEISQEGDEPAREQSVSKIRDQFGEQEGNLATQSSPPKEATQRPCEDQEVRTEKEKHSNIQEPPLQREDEPS-SQHADLPEQAAARSPSQTQKSTDSKDVCRMFDTQEPGKDADQTPAKTKNLGEPEDYGRTSETQEKECETKDLP-----VQYGSRNGSETSDMRDERKERRGPEAHGTAGQKERDRKTRPLVLETQTQDGKYQELQGLSKSKDAEKGSETQYLSSEGGDQTHPELEGTAVSGEEAEHTKEGTAEAFVNSKNAPAAERTLGARERTQDLAPLEKQSVGENTRVTKTHDQPVEEEDGYQGEDPESPFTQSDEGSSETPNSLASEEGNSSSETGELPVQGDSQSQGDQHGESVQGGHNNNPDTQRQGTPGEKNRALEAVVPAVRGEDVQLTEDQEQPARG--EHKNQGPGTKGPGAAVEPNGHPEAQESTAGDENRKSLEIEITGALDEDFTDQLSLMQLPGKGDSRNELKVQGPSSKEEKGRATEAQNTLLESLDEDNSASLKIQLETKEPVTSEEEDESPQELAGEGGDQKSPAKKEHNSSVPWSSLEKQMQRDQEPCSVERGAVYSSPLYQYLQEKILQQTNVTQEEHQKQVQIAQASGPELCSVSLTSEISDCSVFFNYSQASQPYTRGLPLDESPAGAQETPAPQALEDKQGHPQRERLVLQREASTTKQ", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.:***.::**:* ***** ** .: * ** **:**::**:***:** *:****:: ***::* :* ***:**:****.*** *:**. **.** * ::*.** * **: * *. * .**..****: ::*. *: *.* **. . .: *.* .: ***.:* :.** ***:::: : *::**:** : ::* : * : *. : .*:::.** :**.:: .:.:*. * :** * . *** : : *: * *:* **:.*: : * ::**. **: ..****: :. * :: ::* .****.: *.:*. * **: . .: :: : :: ** *** ****. : . * **::* * . . :::* * * **: * :.:*.::.: : ** *:*. **:: ::* ::*.*:::.*. :* .*.:** *.* :***:*:*****:** :: *.:: :*:.*.:** :***.* . ****** .* *****.* *:**** .* * :** * ::**:: * .* ****.*:**.***..* * ** ::: ** **.* **: * ", "identical_positions": 244, "similar_positions": 193, "identity": "26.73%" }, { "cls_id": "homologset.agr.RGD:1308307", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZVU4-1", "uniprot_id": "A0A8I5ZVU4_RAT", "id": "A0A8I5ZVU4-1", "name": "Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial", "aln": "---MLYR---LLSIVQRQR-TSPGWQTWSSARSS--------------------TSAAEAQSIALPAQAQVVICGGGIMGTSVAYHLSKMGWQ-DIVLLEQGRLAAGSTRFCAGILSTARHSSIEQKMADYSNKLYHQLEQETGIQTGYLRTGSISLAQTQDRLISLKRINSRLNVVGIPSEIISPKKVAELHPLLNVHDLVGAMHVPEDAVVSSADVALALASAASQNGVQIYDRTSVLHVLTKKGRVTGVDTDKGQIECQYFVNCAGQWAYELGLSSEEPVSIPLHACEHFYLLTRPCDAPLQSSTPTVVDADGRIYIRNWQGGVLSGGFEKNPKPIFTEGKNQLEIQN--LREDWDHFEPLLSSLLRRMPGLESVEILKLVNCPETFTADMKCIMGESPVVQGYFVLAGMNSAGLSLGGGAGKLLAEWMVYGYPSENVWELDLQRFGALQGSRTFLRHRVMEVMPLIYDLKVPRWDFQTGRQLRTSPLYDRLDAQGARWMEKHGFERPKYFVPPNKD------LLALEQSKTFYKPDWFDIVESEVKCCKEAVCVIDMSSFTKFEITSTGDQALESLQYLFSNDLDVPVGHIVHTGMLNEYGGHENDCSIARLTKRSFFMISPTDQQVHCWAWLHKYLP--KDSNLLLEDVTWKYTALNLIGPRAVDVLSELSYAPMTPDHFPTLFCKEMSVGYANGIRVMSMTHTGEPGFMLYIPIEYALHVYNEVMSVGQKYGIRNAGYYALRSLRIEKFFAFWGQDLNTLTTPLECGGESRVKLEKGIDFIGRDALLQQKQTGVYKRLVMFILDDHDTDLDLWPWWGEPIYRNGKYAGKTTSSAYSYTLERHVCLGYVHNFSEDSGEEQVVTADFINRGEYEIDIAGHRFQAKAKLYP--VTSFFTHKRR---------KDDVELSDFHGK---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TSQ8-1", "uniprot_id": "PDPR_MOUSE", "id": "Q7TSQ8-1", "name": "Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial", "aln": "---MLYR---LLSIVQRQR-TSPGWQTWSSARSS--------------------TSTAEAHSIALPAQAQVVICGGGIMGTSVAYHLSKMGWQ-DIVLLEQGRLAAGSTRFCAGILSTARHSSVEQKMANYSNKLYHQLEQETGIQTGYLRTGSISLAQTQDRLISLKRINSRLNVVGIPSEIISPKKVAELHPLLNVHDLVGAMYVPEDAVVSSADVALALASAASQNGVQIYDRTSVLHVLIKKGQVTGVETDKGQIECQYFVNCAGQWAYELGLSNEEPLSIPLHACEHFYLLTRPWDTPLQSNTPTIVDADGRIYIRNWQGGILSGGFEKNPKPIFTEGKNQLEIQN--LREDWDHFEPLLSSLLRRMPALETLEILKLVNCPETFTPDMKCIMGESPVVQGYFVLAGMNSAGLSLGGGAGKFLAEWMVYGYPSENVWELDLQRFGALQSSRTFLRHRVMEVMPLIYDLKVPRWDFQTGRQLRTSPLYDRLDAQGARWMEKHGFERPKYFVPPNKD------LLALEQSKTFYKPDWFDIVESEVKCCKEAVCVIDMSSFTKFEITSTGDEALESLQYLFCNDLDVPVGHIVHTGMLNEYGGYENDCSIARLTKRSFFMISPTDQQVHCWAWLNKYLP--KDSNLLLEDVTWKYTALNLIGPRAVDVLSELSYAPMTPDHFPTLFCKEMSVGYANGIRVMSMTHTGEPGFMLYIPIEYALHVYNEVMSVGQKYGIRNAGYYALRSLRIEKFFAFWGQDLNTLTTPLECGGESRVKLEKGIDFIGRDALLQQKQTGVYKRLAMFILDDHDTDLDLWPWWGEPIYRNGKYAGKTTSSAYSYTLERHVCLGYVHNFSEDSGEEQVVTTDFINRGEYEIDIAGHRFQAKAKLYP--VTSFFTHKRR---------KDDVELSDFHGK---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NCN5-1", "uniprot_id": "PDPR_HUMAN", "id": "Q8NCN5-1", "name": "Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial", "aln": "--MMFYR---LLSIVGRQR-ASPGWQNWSSARNS--------------------TSAAEARSMALPTQAQVVICGGGITGTSVAYHLSKMGWK-DIVLLEQGRLAAGSTRFCAGILSTARHLTIEQKMADYSNKLYYQLEQETGIQTGYTRTGSIFLAQTQDRLISLKRINAGLNVIGIPSEIISPKKVAELHHLLNVHDLVGAMHVPEDAVVSSADVALALASAASQNGVQIYDRTSVLHVMVKKGQVTGVETDKGQIECQYFVNCAGQWAYELGLSNEEPVSIPLHACEHFYLLTRPLETPLQSSTPTIVDADGRIYIRNWQGGILSGGFEKNPKPIFTEGKNQLEIQN--LQEDWDHFEPLLSSLLRRMPELETLEIMKLVNCPETFTPDMRCIMGESPAVQGYFVLAGMNSAGLSFGGGAGKYLAEWMVHGYPSENVWELDLKRFGALQSSRTFLRHRVMEVMPLMYDLKVPRWDFQTGRQLRTSPLYDRLDAQGARWMEKHGFERPKYFVPPDKD------LLALEQSKTFYKPDWFDIVESEVKCCKEAVCVIDMSSFTKFEITSTGDQALEVLQYLFSNDLDVPVGHIVHTGMLNEGGGYENDCSIARLNKRSFFMISPTDQQVHCWAWLKKHMP--KDSNLLLEDVTWKYTALNLIGPRAVDVLSELSYAPMTPDHFPSLFCKEMSVGYANGIRVMSMTHTGEPGFMLYIPIEYALHVYNEVMSVGQKYGIRNAGYYALRSLRIEKFFAFWGQDINNLTTPLECGRESRVKLEKGMDFIGRDALLQQKQNGVYKRLTMFILDDHDSDLDLWPWWGEPIYRNGQYVGKTTSSAYSYSLERHVCLGFVHNFSEDTGEEQVVTADFINRGEYEIDIAGYRFQAKAKLYP--VASLFTQKRR---------KDDMELSDLHGK---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W4K8-1", "uniprot_id": "Q9W4K8_DROME", "id": "Q9W4K8-1", "name": "Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial", "aln": "MWKLLQRSGNAVSVVPRRRWCSPGLSNAVRLSSSQMDPADERVLRKRKFQPQQAADLSEELAGQLPVKSRVVICGGGITGASVAYHLGLRGWGGETLLVEQDRVGGELPWTACGLAGRFEPSYTELKLAEYSIDLIKRLAEN-GLPTGWRPVGSLNLARSWDRMTAFNRMKSQALAWGMHCEILSPEQCAQHCELLSLDGIEGGLWIPEDGVCDPQLVCQAYMIEAQRLGVRIVEHCAIKKIHSEHGKVRSVETTAGDVECEYFVNCTGFWAREVGTLSKPVVKVPLKAVEHHYLHTKPIEG-LSPDTPFVRDFDGRIFFRECEGHILAGGFEREAKMVYEDGVIPLSQTARQHPPDWDHFHELLDALLLRVPSFRDATLDRLTNSLQVFSPDCKWILGEAPEIQNYYVAAGNKTMGVSASGGIGRVLTDLITKGSTYLDLHILDISRFLGLHNNRKFLRDRCKEAPGKHFEINYPFEEFQTGRNLRMSPIYPQLKEAGAVFGQSMGYERPNYFDQQDKHDEFGLPRFRIAQTRTFGKPPWFDHVASEYRACRERIGIADYSSFTKYDFWSKGNEVVDLLQYLCSNDVDVAVGSIIHTGMQNPNGGYENDCSLARLSERHYMMIAPTIQQTRSMCWIRKHMPNHLRAKVNVADVTSMYTAICILGPYSRILLSELTDTDLTPKSFPFFTYKELDVGLADGIRVLNITHTGELGYVLYIPNEYALHVYSRLYQAGQKFNIQHAGYYATRALRIEKFYAFWGQDLDTFTTPLECGRSWRVKFNKPIDFIGRNALLKQREEGVKRMYVQLLLNDHDHEVDMWCWGGEPIYRDGVYVGMTTTTGYGYTFEKQVCLGFVRNFD-DEGRELPVTNEYVLSGHYEVEVAGVRFEAKVNLHSPNLPTKFPDREREAYHATRDKPDQADLLSYGGVTTVKGTGIPTDGHGL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: * :*:* *:* *** .. .* :. :* : **.:::******** *:******. ** : :*:**.*:.. . ..*: . . * *:*:** .* :* :: *: **: .**: **:: **: :::*::: . *: .**:**:: *: **.:..: *.: :***.* .. *. * *.: **:* :: :: :: ::*:* .*:* *::**:*****:* ** *:* .: :.:**:* **.** *:* : *...** : * ****::*: :* :*:****::.* :: :* *. *****. **.:** *:* :. : :*.*. :.*:.* : *:**:* :*.*:* ** :: *:* .** *: *:: :. * . :: **:.** .*:..*.***.* *. :::: * :*****:** **:* :*. ** : :. *:***:** :*. : : *::** ** *** * ** :.*:* : : * *****::: *.*::.:: **** .**:**.** *:**** * **:*****:***.:* ::**:** **.:. .*:.*::* ::: : *** ***: ::** : :****: : :**. ** : **:.** *:****:.:***** *::**** *******..: ..***:.*::***** *:******:******::.:******* . ***::* :*****:***:*:: ** : . ::*:*** ::*:* * ******:* *.* **::.*.*::*::****:*:**. * *.* ** ::: *.**:::** **:**.:*:. :.: *..:.* *: :* . * ", "identical_positions": 368, "similar_positions": 297, "identity": "39.07%" }, { "cls_id": "homologset.agr.RGD:1308308", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QZM8-1", "uniprot_id": "FBX17_MOUSE", "id": "Q9QZM8-1", "name": "F-box only protein 17", "aln": "MGARPSRRQMTEARRLALTKLPPELLVQVLSHVPPRALVTRCRPVCRAWRDLVDGPSIWLLQLARDRSAEGRALYALAQRCPADADADADADGNRHDEFPFCALARFCLRAPFGRNLIHNSCGEQGFRGWEVEHGGNGWAVEKNLTLVPGAPSQTCFVTSFEWCSKRQLVDLVKEGVWQELLDSGQIEICIADWWGARENCGCIYRLRVRLLDEYENEVVKFSASPNPVLQWTERSCRQVSHVFTNFGKGIRYVSFEQYGRDTRSWVGHYGALVTHSSVRVRIRLS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96EF6-1", "uniprot_id": "FBX17_HUMAN", "id": "Q96EF6-1", "name": "F-box only protein 17", "aln": "MGARLSRRRLPADPSLALDALPPELLVQVLSHVPPRSLVTRCRPVCRAWRDIVDGPTVWLLQLARDRSAEGRALYAVAQRCLP-----SNED---KEEFPLCALARYCLRAPFGRNLIFNSCGEQGFRGWEVEHGGNGWAIEKNLTPVPGAPSQTCFVTSFEWCSKRQLVDLVMEGVWQELLDSAQIEICVADWWGARENCGCVYQLRVRLLDVYEKEVVKFSASPDPVLQWTERGCRQVSHVFTNFGKGIRYVSFEQYGRDVSSWVGHYGALVTHSSVRVRIRLS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6AY27-1", "uniprot_id": "FBX17_RAT", "id": "Q6AY27-1", "name": "F-box only protein 17", "aln": "MGAQPSRRRMTEAQHMALAELPPELLLQVLSHVPPRALVTRCRPVCRAWRDLVDGPSVWLLQLARDRSAEGRALYALAQSCPA------DRNG--HDDFPLCALARFCLLAPLGRNLIYNSCGEQGFRGWEVEHGGNGWAVEKNLTMVPGAPSQTCFVTSFEWCFKRQLVDLVKEGVWQELLDSAQIEIYIADWWGARENCGCIYRLRVRLLDEHENEVVKFSASPNPVLQWTERSCRQVS-------------------PDCSLNPGLLQGLS---------RLH", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***: ***::. :** ******:*********:**************:****::******************:** * . : : :::**:*****:** **:*****.*********************:***** ***************** ******** **********.**** :************:*:******* :*:*********:********.***** * * .* ** ", "identical_positions": 191, "similar_positions": 31, "identity": "66.78%" }, { "cls_id": "homologset.agr.RGD:1308311", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZEH5-1", "uniprot_id": "SIDT2_RAT", "id": "D3ZEH5-1", "name": "SID1 transmembrane family member 2", "aln": "MIAWRLPLCVLLVAAVES-----------HLGALGPKNVSQKDA-------------------------------------EFERTYADDVNSELVNIYTFNHTVTRNRTEGVRVSVNVLNKQKGAPLLFVVRQKEAVVSFQVPLILRGLYQRKYLYQKVERTLCQPPTKNESEIQFFYVDVSTLSPVNTTYQLRVNRVDNFVLRTGELFTFNTTAAQPQYFKYEFPDGVDSVIVKVTSKKAFPCSVISIQDVLCPVYDLDNNVAFIGMYQTMTKKAAITVQRKDFPSNSFYVVVVVKTEDQACGGSLPFYPFVEDEPVDQGHRQKTLSVLVSQAVTSEAYVGGMLFCLGIFLSFYLLTVLLACWENWRQ-RKKTLLVAIDRACPESGHPRVLADSFPGSAPYEGYNYGSFENGSG--STDGLVESTGSGDLSYSYQ-------------------DRSFDPVGARPRLDSMSSVEEDDYDTLTDIDSDKNVIRTKQYLCVADLARKDKRVLRKKYQIYFWNIATIAVFYALPVVQLVITYQTVVNVTGNQDICYYNFLCAHPLGNLSAFNNILSNLGYILLGLLFLLIILQREINHNRALLRNDLYALECGIPKHFGLFYAMGTALMMEGLLSACYHVCPNYTNFQFDTSFMYMIAGLCMLKLYQKRHPDINASAYSAYACLAIVIFFSVLGVVFGKGNTAFWIVFSVIHIISTLLLSTQLYYMGRWKLDSGIFRRILHVLYTDCIRQCSGPLYTDRMVLLVMGNIINWSLAAYGLIMRPNDFASYLLAIGICNLLLYFAFYIIMKLRSGERIKLIPLLCIVCTSVVWGFALFFFFQGLSTWQKTPAESREHNRDCILLDFFDDHDIWHFLSSIAMFGSFLVLLTLDDDLDTVQRDKIYVF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CIF6-1", "uniprot_id": "SIDT2_MOUSE", "id": "Q8CIF6-1", "name": "SID1 transmembrane family member 2", "aln": "MIAWRLPLCVLLVASVES-----------HLGALGPKNVSQKDA-------------------------------------EFERTYADDVNSELVNIYTFNHTVTRNRTEGVRVSVNVLNKQKGAPLLFVVRQKEAVVSFQVPLILRGLYQRKYLYQKVERTLCQPPTKNESEIQFFYVDVSTLSPVNTTYQLRVNRVDNFVLRTGELFTFNTTAAQPQYFKYEFPDGVDSVIVKVTSKKAFPCSVISIQDVLCPVYDLDNNVAFIGMYQTMTKKAAITVQRKDFPSNSFYVVVVVKTEDQACGGSLPFYPFVEDEPVDQGHRQKTLSVLVSQAVTSEAYVGGMLFCLGIFLSFYLLTVLLACWENWRQ-RKKTLLLAIDRACPESGHARVLADSFPGSAPYEGYNYGSFENGSG--STDGLVESAGSGDLSYSYQ-------------------DRSFDAVGPRPRLDSMSSVEEDDYDTLTDIDSDKNVIRTKQYLCVADLARKDKRVLRKKYQIYFWNIATIAVFYALPVVQLVITYQTVVNVTGNQDICYYNFLCAHPLGNLSAFNNILSNLGYILLGLLFLLIILQREINHNRALLRNDLYALECGIPKHFGLFYAMGTALMMEGLLSACYHVCPNYTNFQFDTSFMYMIAGLCMLKLYQKRHPDINASAYSAYACLAIVIFFSVLGVVFGKGNTAFWIVFSVIHIISTLLLSTQLYYMGRWKLDSGIFRRILHVLYTDCIRQCSGPLYTDRMVLLVMGNIINWSLAAYGLIMRPNDFASYLLAIGICNLLLYFAFYIIMKLRSGERIKLIPLLCIVCTSVVWGFALFFFFQGLSTWQKTPAESREHNRDCILLDFFDDHDIWHFLSSIAMFGSFLVLLTLDDDLDTVQRDKIYVF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NBJ9-1", "uniprot_id": "SIDT2_HUMAN", "id": "Q8NBJ9-1", "name": "SID1 transmembrane family member 2", "aln": "MFALGLPFLVLLVASVES-----------HLGVLGPKNVSQKDA-------------------------------------EFERTYVDEVNSELVNIYTFNHTVTRNRTEGVRVSVNVLNKQKGAPLLFVVRQKEAVVSFQVPLILRGMFQRKYLYQKVERTLCQPPTKNESEIQFFYVDVSTLSPVNTTYQLRVSRMDDFVLRTGEQFSFNTTAAQPQYFKYEFPEGVDSVIVKVTSNKAFPCSVISIQDVLCPVYDLDNNVAFIGMYQTMTKKAAITVQRKDFPSNSFYVVVVVKTEDQACGGSLPFYPFAEDEPVDQGHRQKTLSVLVSQAVTSEAYVSGMLFCLGIFLSFYLLTVLLACWENWRQ-KKKTLLVAIDRACPESGHPRVLADSFPGSSPYEGYNYGSFENVSG--STDGLVDSAGTGDLSYGYQ-------------------GRSFEPVGTRPRVDSMSSVEEDDYDTLTDIDSDKNVIRTKQYLYVADLARKDKRVLRKKYQIYFWNIATIAVFYALPVVQLVITYQTVVNVTGNQDICYYNFLCAHPLGNLSAFNNILSNLGYILLGLLFLLIILQREINHNRALLRNDLCALECGIPKHFGLFYAMGTALMMEGLLSACYHVCPNYTNFQFDTSFMYMIAGLCMLKLYQKRHPDINASAYSAYACLAIVIFFSVLGVVFGKGNTAFWIVFSIIHIIATLLLSTQLYYMGRWKLDSGIFRRILHVLYTDCIRQCSGPLYVDRMVLLVMGNVINWSLAAYGLIMRPNDFASYLLAIGICNLLLYFAFYIIMKLRSGERIKLIPLLCIVCTSVVWGFALFFFFQGLSTWQKTPAESREHNRDCILLDFFDDHDIWHFLSSIAMFGSFLVLLTLDDDLDTVQRDKIYVF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9P7I2-1", "uniprot_id": "A0A8M9P7I2_DANRE", "id": "A0A8M9P7I2-1", "name": "", "aln": "MTSHRRAVSTQQRDGERVRTDAGWRTDRIYIGSTSVSVFSQADAGSRMLWWCCGSVLRLVLMLVFLFCCPAVSSTNDVVPAQFDVTYFDTVTSEKQTIYSYNHTVSRNKTEGVRVSVELQSESALSPILFVVRQKQAVLSFQVPLILRGLYQRKYQYTQVSRTLCQPPTKAMSETQFFYVDVSTLASSGISYQLRVSRVDSFTLQTDKKFSFNATPSQPQFFKYVFPEGVDTVIVKVNSQKNFPCSVMSIQDIQCPVYDLDNNVAFIGMYQTMTTRSAITVQRKDFPSNSFYVVVVVKTEDEACGGPLRFYPLLPDELLDAGNRSKTLDVIVSPAINSEVYVMGMLFCLGIFLSFYLLTFLVACLENKRMNRKREGLLNPDTSPAET-------ASLLGKAPVSPYEYGSFADNGSTLSSEAVTDSLTSTDGNYGYMGSETFKRRLVTAHHVAIRFERSLESIS-RSRQESLSSVEEDDYDTLADIDSDKNIVRTKKFLCVSDLARKDKRILSKKYQIYFWNIATIAVFYALPVIQLVITYQTVVNVTGNQDICYYNFLCAHPLGALSSFNNILSNLGYVLLGLLFLLIVLQRDILHNRALERNDNTALECGIPKHFGLYYAMGTALMMEGLLSACYHVCPNYTNFQFDTSFMYMIAGLCMLKLYQKRHPDINASAYSAYACLAAVIFFSVLGVVFGKGNMAFWIVFSVIHILATMLLSTQLYYMGRWRLDSGIMRRMLYVIYTDCIRQCSGPMYIDRMVLLVMGNIVNWSLAAYGLINRPNDFASYLLAIAICNLLLYFAFYIIMKLRSGERIQCLALVCVLFTAVVWGFALFFFFQGLSTWQKTPAESREHNRECILLSFFDDHDIWHFLSSIAMFGSFLVLLTMDDDLDSVQRDKIYVF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : .. . . . ::* . . .** ** :*: ** * *.** .**::****:**:********:: .:. :*:*******:**:**********::**** * :*.********* ** **********:. . :*****.*:*.*.*:*.: *:**:*.:***:*** **:***:*****.*:* *****:****: ********************.::************************:****.* ***: ** :* *:*.***.*:** *:.**.** ****************.*:** ** * :*: *: * : .*: *: *.:* . *:**** : .. *::.:.:* : * .*.* **::.:. *.* :*:***********:*******::***::* *:********:* *********************:****************************** **:**********:*********:***:* ***** *** ************:**************************************************************** *************** *******:***::*:************:*****:**:*:*:***********:* **********::********** ************.**********************: :.*:*:: *:*****************************:****.*************************:*****:*********", "identical_positions": 609, "similar_positions": 138, "identity": "67.52%" }, { "cls_id": "homologset.agr.RGD:1308312", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4AAZ8-1", "uniprot_id": "D4AAZ8_RAT", "id": "D4AAZ8-1", "name": "", "aln": "-MASVQAS-RRQWCYLCDLPKMPWAMVWDFSEAVCRGCVNFEGADRIELLIDAARQLKRSHVLPEGRSPGP-PALKH-PTSKDLASTGSQGSQLPPPQAQAQPSGTGGSVSGPDRYDRATSSS--RLALPSPALEYTLGSRLANGLGREEAVAEGARRALLGSIPSLMPPGLLAAAVSG----LGGRALTLAPGLSPARP-LFGSDFEKE--KQQRNADCLAELNEAMRGRAEEWHGRPKAVREQLLALSACAPFNVRFKKDHGLVGRVFAFDATARPPGYEFELKLFTEYPCGSG--------NVYAGVLAVARQMFHDALREPGKALASSGFKYLEYERRHGSG----EWRQLGELLTDGVRSFREPAPAEALP-----QQYPEPAPAALCGPPPRAPSRNLAPTPRRRKASPE---------PEGETAGKMTTEEQQQ-----------RHWVAPGGPYSTETPG----VPSPIAALKNVAEALGHSPKDPGGGGGSVRAGGASPAASSTTQPPTQHRLVARNGEAEVSPTAG------AEAVSGGGSGTGATPGAPLCCTLCRERLEDTHFVQCPSVPGHKFCFPCSREFIKAQ-GPAGEVYCPSGDKCPLVGSSVPWAFMQGEIATILAGDIKVKKERDP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R3Y8-1", "uniprot_id": "I2BP1_MOUSE", "id": "Q8R3Y8-1", "name": "Interferon regulatory factor 2-binding protein 1", "aln": "-MASVQAS-RRQWCYLCDLPKMPWAMVWDFSEAVCRGCVNFEGADRIELLIDAARQLKRSHVLPEGRSPGP-PALKH-PTSKDLASTGSQGSQLPPPQAQAQPSGTGGSVSGPDRYDRATSSS--RLALPSPALEYTLGSRLANGLGREEAVAEGARRALLGSIPSLMPPGLLAAAVSG----LGGRALTLAPGLSPARP-LFGSDFEKE--KQQRNADCLAELNEAMRGRAEEWHGRPKAVREQLLALSACAPFNVRFKKDHGLVGRVFAFDATARPPGYEFELKLFTEYPCGSG--------NVYAGVLAVARQMFHDALREPGKALASSGFKYLEYERRHGSG----EWRQLGELLTDGVRSFREPAPAEALP-----QQYPEPAPAALCGPPPRAPSRNLAPTPRRRKASPE---------PEGETAGKMTTEEQQQ-----------RHWVAPGGPYSSETPG----VPSPIAALKNVAEALGHSPKDPGGGGGSVRAGGASPAASSTTQPPAQHRLVARNGEAEVSPTAG------AEAVSGGGSGTGATPGAPLCCTLCRERLEDTHFVQCPSVPGHKFCFPCSREFIKAQ-GPAGEVYCPSGDKCPLVGSSVPWAFMQGEIATILAGDIKVKKERDP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IU81-1", "uniprot_id": "I2BP1_HUMAN", "id": "Q8IU81-1", "name": "Interferon regulatory factor 2-binding protein 1", "aln": "-MASVQAS-RRQWCYLCDLPKMPWAMVWDFSEAVCRGCVNFEGADRIELLIDAARQLKRSHVLPEGRSPGP-PALKH-PATKDLAAAAAQGPQLPPPQAQPQPSGTGGGVSGQDRYDRATSSG--RLPLPSPALEYTLGSRLANGLGREEAVAEGARRALLGSMPGLMPPGLLAAAVSG----LGSRGLTLAPGLSPARP-LFGSDFEKE--KQQRNADCLAELNEAMRGRAEEWHGRPKAVREQLLALSACAPFNVRFKKDHGLVGRVFAFDATARPPGYEFELKLFTEYPCGSG--------NVYAGVLAVARQMFHDALREPGKALASSGFKYLEYERRHGSG----EWRQLGELLTDGVRSFREPAPAEALP-----QQYPEPAPAALCGPPPRAPSRNLAPTPRRRKASPE---------PEGEAAGKMTTEEQQQ-----------RHWVAPGGPYSAETPG----VPSPIAALKNVAEALGHSPKDPGGGGGPVRAGGASPAASSTAQPPTQHRLVARNGEAEVSPTAG------AEAVSGGGSGTGATPGAPLCCTLCRERLEDTHFVQCPSVPGHKFCFPCSREFIKAQ-GPAGEVYCPSGDKCPLVGSSVPWAFMQGEIATILAGDIKVKKERDP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LV17-1", "uniprot_id": "I2BP1_DANRE", "id": "Q1LV17-1", "name": "Interferon regulatory factor 2-binding protein 1", "aln": "MSSSSQASSRRQWCYLCDLPKMPWAMIWDFSEAVCRGCVNYEGADRIELLIDTARQLKRTHVMQDGRSPGPQPGGKHGPAGKEGPMEAGR----PPSERYERGRGEYVSARLPNGLPRLEDGGPPEVSRQSPTARRTLVGAVPPNLMAQGLV--GAPHGLLTAMPLNPRAGSAALTIPAPMLNEISKRQALSMGLSVGVPSFMAPEFEKEFKEKQRNAEALAELSESVRNRADDWAGRPKPMRDALHTLSGCTPFNVRFKKDHGLVGRVFAFDAKLM---VEFELKIFIEYPCGSG--------NVFPSILALVKHMFHDSQKDTGKVIN-SGYKYVEYEKRHGTG----DWRLLSELLSDAVRAFKEMPAPDALP-----QPYLD-ASCSMLPTALCHIGRPTQPRVRRRKASPD---------PDG--AERMSSEELRQHWPLSAYPGIPGHMPATSLASAGQAPEGHGSDPSPITALMSVADNVGTASSKDGPGSSGHSANAGRQNSTSPSPGGGQRRLASRNGEPSAGSSTGGPATVTDQSAVMGGEGSAGGGGAPLCCTICQERLEDTHFVQCPSVAGHKFCFPCTRDFIRRQ-GPGSEVYCPSGEKCPLVGSNVPWAFMQGEISTILAGDVKVKKERDP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B7Z143-1", "uniprot_id": "B7Z143_DROME", "id": "B7Z143-1", "name": "", "aln": "----MSLQTKRQHCYLCDLPRMPWAMINDFSEAVCRGCVNYEGADRIEAVLDAARQMKRLHPASKQQRSHE-NGEVSAAAAAAVVLQQQQQLQVGPVPGQGPGSHRGGGGGGPPGAPPGSGGP-----GPSGAGSLSSLGNAVAAAAAAAAVHHHHQMPYQMPVPRIGPPLDYPVKLED-----APGGGVRPVRISHMTPHHLPPNATRGGGGAPGGGVPTAGSGGGSLPPALSVNLKRPPSEDVDVDVSQQQQQSGHGLAPDGSAGNSLSAGGGVSGGCPPGIKRSAMDDPSGVGGRPPLTRGESLPAAVSYVPERQLSGLRDKQQPVRAPSFDASTFKAANPIPNPIPHHLHIAEHMSPASRRNGSSPPSGPLPPRSVHSPNSSGSSSGRRSSGSRHVSSTTVTSSEVGGSNPGQAVVAGGLGGGGGGGPGSNAASGQLGGPSGGSGQLSCTSGGPGGSASSGSGGNGAIGPASMAPNSVAGDGSPAGGNGPSGSNGSGGSVNPGPGSSGSQGGGGGGTPLASGGGSAGSGGLGGAPGSSAASNSAAAAAAAAAQNATLKCTLCQERLEDTHFVQCPSVNHHKFCFPCSRESIKRQNGLGNEVYCPSGDRCPLANSVIPWAFMQGEITTILGEEVKVKKERES", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . :** *******:*****: ************:******* ::*:***:** * . : . . .: : * . .. * : : . * .:* . . : . . :* * : .: : .. * . . * . : . .: :* . : .* .*. :: .. : : *.* * : .. :: . . .. :: : : ..:. :: : . :.* :: . * . ... .** . . :... . . . . :.* * . .: . : ... . : : *:.::. ..: . . . ... : ::.. : .* . . * : .. .:.. .*.* **:*:************** *******:*: *: * * ..*******::***..* :*********:***. ::******:.", "identical_positions": 122, "similar_positions": 161, "identity": "18.91%" }, { "cls_id": "homologset.agr.RGD:1308313", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P52623-1", "uniprot_id": "UCK1_MOUSE", "id": "P52623-1", "name": "Uridine-cytidine kinase 1", "aln": "-------------------MASAGGGGSESAAPEADRPQPRPFLIGVSGGTASGKSTVCEKIMELLGQNEVDRRQRKLVILSQDCFYKVLTAEQKAKALKGQYNFDHPDAFDNDLMHKTLKNIVEGKTVEVPTYDFVTHSR-LPETTVVYPADVVLFEGILVFYTQEIRDMFHLRLFVDTDSDVRLSRRVLRDVQ-RGRDLEQILTQYTAFVKPAFEEFCLPTKKYADVIIPRGVDNMVAINLIVQHIQDILNGDLCKRHRGGPN----GRNHKRTFPEPGDHPGVLAT--GKRSHLESSSRPH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7EXY3-1", "uniprot_id": "F7EXY3_RAT", "id": "F7EXY3-1", "name": "Uridine-cytidine kinase", "aln": "MKVLAGAGRVGGCMSAAPEMASAGGGGSESAAPEADRPQPRPFLIGVSGGTASGKSTVCEKIMELLGQNEVDRRQRKLVILSQDCFYKVLTAEQKAKALKGQYNFDHPDAFDNDLMHKTLKNIVEGKTVEVPTYDFVTHSR-LPETTVVYPADVVLFEGILVFYTQEIRDMFHLRLFVDTDSDVRLSRRVLRDVQ-RGRDLEQILTQYTAFVKPAFEEFCLPTKKYADVIIPRGVDNMVAINLIVQHIQDILNGDLCKRHRGGPN----GRNYKRTFPEPGDHPGVLAT--GKRSHLESSSRPH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9HA47-1", "uniprot_id": "UCK1_HUMAN", "id": "Q9HA47-1", "name": "Uridine-cytidine kinase 1", "aln": "-------------------MASAGGEDCESPAPEADRPHQRPFLIGVSGGTASGKSTVCEKIMELLGQNEVEQRQRKVVILSQDRFYKVLTAEQKAKALKGQYNFDHPDAFDNDLMHRTLKNIVEGKTVEVPTYDFVTHSR-LPETTVVYPADVVLFEGILVFYSQEIRDMFHLRLFVDTDSDVRLSRRVLRDVR-RGRDLEQILTQYTTFVKPAFEEFCLPTKKYADVIIPRGVDNMVAINLIVQHIQDILNGDICKWHRGGSN----GRSYKRTFSEPGDHPGMLTS--GKRSHLESSSRPH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q66I71-1", "uniprot_id": "UCK1_DANRE", "id": "Q66I71-1", "name": "Uridine-cytidine kinase 1", "aln": "-------------------MNSSG------LLCDNERPRHRPFLIGVSGGTASGKSTVCAKIMELLGQNKVDHHQRKVTIVSQDSFYRVLTPEQKAKALKGQYNFDHPDAFDTEFMCQTLKDIVEGKVVEVPTYDFVTHSR-LPEKICVYPADVVLFEGILVFYTQEVRDMFHMKQFVDTDSDVRLSRRVLRDMN-RGRDLEQILTQYTTFVKPAFEEFCLPTKKYADVIIPRGVDNMVAINLIVQHIQDILNGDICKWQRGSVNGHNHGRSLKRGVAEHGENPSGSSSNLTKRPLLEPSTRPH", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VC99-1", "uniprot_id": "UCK_DROME", "id": "Q9VC99-1", "name": "Uridine-cytidine kinase", "aln": "---------------MQDLRNADTLRLPNGDGAAANDEVKSPFLIGVAGGTASGKSTVCKKIMEQLGQAEMDHTQRQVVSISQDSFYRELTPAEKAKAQKGLFNFDHPDAFNEELMYSTLQNILKGHKVEIPSYDYRTNSLDFENVLVIYPADVVLFEGILVFYFPKIRELFHMKLFVDTDSDTRLARRVPRDINERGRDLDAVLTQYMTFVKPAFEEFCSPTKKFADVIIPRGADNTVAIDLIVHHIGEILATTNSAQHSNTVR--------------------VAAS---------SMKRDH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12084-1", "uniprot_id": "DAS2_YEAST", "id": "Q12084-1", "name": "Putative uridine kinase DAS2", "aln": "--------------------------------MDRKAVEEKRIVISIGGGHATGVGAIALDLQNTFKS------------LYNSINIRVINLDNMIEGNIKSYN-------NNDYDFDNILNLVYEKHAVTSQNDMIQHDY-------EDPIDLIIVCGCYALYDKRINEISQLKVFLDSDADKRLISLIKKKNVGSNEQLAQLITEYMDHLRPEMQQYIEPTRTFADLIIPS-TNENLGRAVLVDGIVKAIEDTKSQIEGNNTN----NKIRPRLWDFEAETMDLEKD--------RYYDLS-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ::*.:.** *:* .::. .: : : . : :. : :. : :. :* : : .: ::: : . . * :. * *:::. * .:* .:.:: ::: *:*:*:* ** : :. ..:* ::*:* .::* :::: **:.:**:*** .:: :. ::*. * . : . . . . ", "identical_positions": 30, "similar_positions": 89, "identity": "9.87%" }, { "cls_id": "homologset.agr.RGD:1308314", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M9PLT8-1", "uniprot_id": "A0A8M9PLT8_DANRE", "id": "A0A8M9PLT8-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGSMNHPKHFKSGETQNDLGSAHQKRSD------------------------------------------------PEPSCVSMKSDWSMNHPIKFKSGDTKNDLSSVQK-RSD-PEPSCVSMKSDWSMDPPMQFKSKDTPPDL---SSVHQERSEP-EPSCMSMNS-DLPLDPPIRYKSG-----------------------------------------------------ETQNDLSPQVFNTFRSNLLKKFECLYEGTAAQGNPTLLNEIYTELYITESKSGEISHEHEVRQIETQSRRSTTEDTAIKCRDIFTPLPG---------QDKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQD-VQLIFPLPFREINLMKD-KTLSLSDLLQLFFPQTKEMEI--SSDKYKVLFIFDGLDECRLSLDFQSAVRLCDVSESASVDELLTNLIVGNLLPSALIWITSRPAAADLVPSECVH-RVTEVRGFNDPQKEEYFSKRISDQSLANTIISHLKSSRSLYIMCHIPVFCWISATVLEKMLS----------------EAETAE----IPKTLTQMYTHFLILQTNIKHQKDYE----EKLTDED----MILKLGKVAFQQLMKGNIIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFVHLSIQEHLAALYVHLSCINKSINQFNFAAKQ-------------------------SLWSKT--KFMFKT---VALSELHQRAVVETLQSKNGHLDLFLRFLLGLSVESHQILLQRPLK-LKRRSIKNNKTVEYIKKKIR--TIDSPEKSINLFHCLNELGDHSLVE-------EIQQYLKSG---GINEAKLSSSQWSAVAFVLLTSEKKLEEFNINEFVAE-------NNKTEKLVIFKKLLPVIRECRSVQLYNCGLTGEGCAALASALISNPEHLTDLNLSRNNLGDSVTLLSAV-LEDPHCKLEKLWLSYCGVT--------------------------------------------------------------------------------------------------------------------DEGCAALVSALRSNPEHLRELNLSGNNLGD-SVTLLSAVLEDPHCKLEKLRLY-------------------------------------------------------------------YCGLTDEGCAALASALRSNPEHLRDLDLSWNKLGDS-VTLLSAVLEDPRCKLEKLELYNCGLTDEGCAALASALRSNPE----------------HLRDLNLSGNKLGDS-VTLLSAVLEDPRCKLE--------------------------------------------------------------------------------------------------KLWLSDCGLTDEGCA---------------------------------ALASALRSN-------------PEHLTELDLSWNNLSKST----------------------------------------------VRLFSDLKD---NPHNKLKTLHI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9PCI8-1", "uniprot_id": "A0A8M9PCI8_DANRE", "id": "A0A8M9PCI8-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEDTQTTIEKDYSP-----------------------RFSLVHQKRSEPSCVS-IRRDQSVAHPIDFKSEDTQTHLSSVHQERLD------------------------------------------------PEPSCVSIRSDRSVAHPIDFKSKNTH--LSSVHQERSE-PEPSCVSIRSDRSVAHPIDFKSEDTQTHL---STFHQKRKEA-DPSCVSMRS-DTFMNQPINIKIG-----------------------------------------------------ETQNDLKQNLLNTFRSNLLKKFECLYEGTAVQGNPTLLNEIYTELYITESESGEISHEHEVRQIETQSRRSTTEDTAIKCRDIFTPLPG---------QNKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQD-VQLIFPLPFREINLMKD-KTLSLSDLLQLFFPQTKEMEI--SSEKYKVLFIFDGLDECRLSLDFQSAVRLCDVSESASVDVLLTNLIVGNLLPSALIWITSRPAAADLVPSECVH-RVTEVRGFNDPQKEEYFSKRISDQSLANTIISHLKSSRSLYIMCHIPVFCWISATVLEKMLS----------------EAETAE----IPKTLTQMYTHFLILQTNIKHQKDYE----EKLTDED----MILKLGKVAFQQLMKGNIIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFVHLSIQEHLAALYVHLSCLNNNRNEFEQISKQ-------------------------SLWSKVRDHFHFNSSKLVSISKLHQRAVNEALQSKNGHLDLFLRFLLGLSVESHQILLQGLMK-LKIRSIQNNETVEYIKKKIR--KINFPEKFINLFHCLNELGDHSLVE-------EIQQFLKSG---GMNEAKLSSSQWSAVVFVLLTSEKKLEKFDINEFAAR-------NNNTEQLFIFKKLQPVIRQCRSVQLSYCGLTDEGCAALASALRSNPEHLRDLYLSGNKLGDSVSLLSGV-LEDPHCKLETLWLSDCGLTSKDSAALASALRSNPEHLRVLDLSWNRL-GDSVTLLSAVLEDPHCKLETLLLRDCG----------------------------------------------------------LTDEGCAALASALRSNPEHLKHLDLSWSNLGD-SVTLLSAVLEDPRCKLEKLGLS-------------------------------------------------------------------NCGLAEEGCAALASALRSNPEHLRGLNLSVNNLGDS-VTLLSAVLEDPRCKLEKIKLSYCGLTDEGCAALASALRSNPE----------------HLRDLDLSTNNLGDS-VTLLSAILEDPHCKLE--------------------------------------------------------------------------------------------------KLELKNCGLTDEGCA---------------------------------VLASALRSN-------------PEHLRDLNLSWNNLSNST----------------------------------------------KKLLSDLKD---DPHNKLETLHTSLSV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32TA29-1", "uniprot_id": "A0AB32TA29_DANRE", "id": "A0AB32TA29-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEDTKISKDEDYSPRFSSVHQERSD------------------------------------------------LEPSCVSMRSEQSMGSPMHFRSEDTEADLSSVYQKRSD-PEPSCVSMRSDWSMDLPYNFRSEDTPTDL---SSFHHKRTEA-EFSRVSMRS-DMFINHPINIKNV-----------------------------------------------------EAQCNIRQNLLNTFRSNLLKKFECLYEGTAAQGNPTLLNEIYTELYITESESGEISHEHEVRQIETQSRRSTTEDTAIKCRDIFTPLPG---------QDKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQD-VQLIFPLPFREINLMKD-KTLSLSDLLQLFFPQTKEMEI--SSDKYKVLFIFDGLDECRLSLDFESAVRLCDISESASVDVLLTNLIVGNLLPSALIWITSRPAAADLVPSECVH-RVTEVRGFNDPQKEEYFSKRISDQSLANTIISHLKSSRSLYIMCHIPMFCWISATVLEKMLS----------------EAETAE----IPKTLTQMYTHFLILQTNIKHQKDYE----EKLTDED----MILKLGKVAFQQLMKGNIIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFVHLSIQEHLAALYVHLSCINNNRDEFEQIKKQ-------------------------SLWFKVKDLFQLNSLECVSLFSLHQRAVNEALQSKNGHLDLFLRFLLGLSVESHQILLQRLMK-LKSRSMQTNKTVKYIKMKIW--TIDSPEKSINLFHCLNELGDHSLVK-------EIQQYLKSG---RINRAKLSSSQWSAVAFVLLTSEKKLEEFNINEFVAG-------NNENKKQKVFQKLLPVIKQSRSVLLYNCGLTEMDWDNLTSALRSNPSDLRVLNLSRNILGNSVTLLSAV-LEDPCSKLEKLWLSDCGLTDEGCAALATALRSNPEHLRELNLSWNNL-RDSVTLLSAVLEDPRCKLETLWLSKCG----------------------------------------------------------ITGKSCAVLASALRSNPEHLRDLDLSGNKLGD-SVTLLSAVLEDPHCKLKILWLS-------------------------------------------------------------------DCGLTDEGCAALASALRSNPGQLRVLDLSENKLKNSGVMQLCAVLEDPHCKLDKLGLYDCSLTDEGCVALASALRSNPE----------------HLRELDLSVNKLRDSGIKLLSAVLEDPRCKLE--------------------------------------------------------------------------------------------------KLWLSNCGLTDEACA---------------------------------ALASALRSN-------------PEHLRELNLSKNKLGESD----------------------------------------------VKLLSDLKD---DTHYKLKELNY--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3AQ59-1", "uniprot_id": "A0A8M3AQ59_DANRE", "id": "A0A8M3AQ59-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLKIFQN--------LTAESGKG------------------------------------------------IRDYVVQIRFCFIMDDTQISRDENVSPGCSSVHQKRSD-PEPSCVSMRSDWSMDPPISFKSKDTPPDF---SSVHQKSTES-EPSCVSMRSDDESVDQPLHVRSG-----------------------------------------------------DTETDLSHEALNTFRSDLLKKFECLYEGTAAQGNPTLLNEIYTELYITESESGEISHEHEVRQIETQSRRSTTEDTAIKCRDIFTPLPG---------QDKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQD-VQLIIPLPFREINLMKD-KTLSLSDLLQLFFPQTKEMEI--SSDKYKVLFIFDGLDECRLSLDFQSAVRLCDVSESASVDVLLMNLIVGNLLPSALIWITSRPAAADLVPSECVH-RVTEVRGFNDPQKEEYFSKRISDQSLANTIISHLKSSRSLYIMCHIPVFCWISATVLEKMLS----------------EAETAE----IPKTLTQMYTHLLILQTNIKHQKDYE----EKLTDED----MILKLGKVAFQQLMKGNIIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFVHLSIQEHLAALYVHLSCINNNRDGFEEIKKP-------------------------SLWSKVKDLLYLNSSQLVSLSELHQRAVNEALQSKNGHLDLFLRFLLGLSVESHQIILQRLMI-LKSRSIQINKTVEYIKMKIR--TIDSPEKFINLFHCLNELGDHSLVE-------EIQQYLKSG---RINRAKLSESQWSAVAFVLLTSEKKLEEFHINEFVG----------ETEKIFIFMKLLPVIRECRSVQLN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NCGLTDEGCAALASALRSNPE----------------HLRELNLSGNRLGDS-VTLLSALLEDPRCNLE--------------------------------------------------------------------------------------------------ILWLSYCGLTDEGCA---------------------------------ALASALRLN-------------PEHLRELNLSHNNISKST----------------------------------------------VKLLSDLKH---NPHNKLETLYI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M6YSM0-1", "uniprot_id": "A0A8M6YSM0_DANRE", "id": "A0A8M6YSM0-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSHKQTLKYFSP-----------------------VCSSVQQERSDSAEPSSVSVKSHWSIDPPPQMTERRDSLSLALQERSDSPEPSHV--------------SMKSDWSIDPPPQMKEENRSLVQQERSPKSSCVSMKRDWSIDPPPQMNDEDGQKRLSLVQQERSDSAEPSLVSMKSDWSIDPPPQMKDGDRQKSL---SLVQQERSDSPEPSHVTMKS-NWSIDPPPQMTDRRDSLRQIPRPRPG------------------AEEPISKKMKYDESVIKSQECMENPSLIFSHEVNTFRVNLLKKFQCLYEGMVTQDNPALLNEIYTELYITESESGEISNEHEVRQIETQSRRSTTEDTAIKCRDIFTPLPG---------QDKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQD-VQLIFPLPFREINLMKD-KTLSLSDLLQLFFPETKEIDI--FSDKYKILFIFDGLDECRLLLNFKSNEILQHVTKTSSVDVLLTNLIVGNLLPSALIWITSRPAAADLVPSECVH-RVTEVRGFNDPQKEEYFSKRISDQSLANTIISHLKSSRSLYIMCHIPVFCWISATVLEKMLS----------------EAETAE----IPKTLTQMYTHFLMAQINTKDMKYTG----KK--DKD----MIFKLGKLAYEQLERGNVIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFIHLSVQEHLAALYVHLLFTNHNRNVFEQMTKKT------------------------SKTLDILDCFHSNSPENVLLSELHQKAVDEALQSKNGHLDLFLRFLLGLSLESNQILLQELMIKFRSSSDSSEKTVEYIKKRIN--NICLPEKSINLFYCLNELGDHSLVK-------EIQQYMDYG---TLAETKISCGQWSALVFILLTVEQAMDVFELNKFIGL-------KKSSDE--VLRKLLPVIKKSRSAIMDDCNITAEGCAYLASALGSNPSYLRELDLSANKLQDS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GIKKLSKGLQDSHCKLEKLNLY-------------------------------------------------------------------HCGVTNEGCAALASALKSNPEHLRDLNLSENKIGNLGLTCLSEILKNSLCKLEILRLCQCGITD--CTDLASALISNPE----------------HLRELELSLNKIGDSGVTALCAAFEDPRFKLE--------------------------------------------------------------------------------------------------KLGLSGCGLTDEGCA---------------------------------ALTSALRSN-------------HEHLRDLDLSGNKVDKEV----------------------------------------------KGSILQRIL---EKLNNIQILSV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E7FA88-1", "uniprot_id": "E7FA88_DANRE", "id": "E7FA88-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MYCNYNMDNTRSSRDEDIYSCTSRESE---------------------------------------------------EVLSNTSYWSLPSYFRHR----KFHRSSVHEKISDSSESSRVSLKSDWSMNPPPLLGEERKSSNLNMSSLVSVRSDWSMDPPPLLRAKGKSAVSSGVSDNIDWLVCS------------------------------------------------PYLRVERKSSALRHKLSLLKKFQCLYEGTAVQGKPTLLNEIYTELYITESESGEISHEHEVRQIETQSRRSTTEDTAIKCRDIFTPLPG---------QDKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQD-VQLIFPLPFREINLIKD-KKFSLVSLLQTFFTREIHLDM--IQN-SAVIFIFDGLDECRLPFNFSRNEILLDVTKETSVDVLLTNLIVGNLLPYALIWITSRPAAADLVPSECVH-RVTEVRGFNDPQKEEYFSKRISDQSLANTIISHLKSSRSLYIMCHIPVFCWISATVLEKMLS----------------EAETAE----IPKTLTQMYTHFLILQTNIKHQKDYE----EKLTDED----MILRLGKLAFQQLMKGNIIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFVHLSIQEHLAALYVHLLFTNHNINVFEQMTKSFEGTPLNKSDLQSLTLNMELFEISEPVLTDVAAMCEMDWRVVNEISALHCKAVDEVLQNKNGHLDLFLRFLLGLSVECNQILLQRLTK-QRRHLYNDNKTVEYIKKKIR--TINSPEKSISLFHCLNELGDHSLVE-------EIQQYLTSG---KIKEFKLSSSQWSAVAFVLLTSEKKLEEFWLKEFVG---------AETKADHVLQKLLPVVKESRKAELSKCGLTEECCAALASALRSKLSHVRELDLSGNKLGDS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GIENLSTGLENLHCKLEILRLR-------------------------------------------------------------------SCGITAKGCTALASALRSNPEQIRQLDLSENNIRDWGVKHLFTELKNPDCKLEILGLRNCGITIEGCAALTSALIINPS----------------HLRELDISRNSLGDTGQELLTSLLNSQHHKLE--------------------------------------------------------------------------------------------------ILLLHKFPMT---------------------------------------FTSLPSSH-------------SPEMFPQRFRTHNLKE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58HZJ9-1", "uniprot_id": "A0AC58HZJ9_DANRE", "id": "A0AC58HZJ9-1", "name": "", "aln": "MVDKEASNDGDFSSRRSHFQSQKSNTSESNPEITPEDLSAKKLIKMFEKRTPDNQSKFNNQKSNTAKSIRSDRSIQNPVKIKEIRTPADLSSQRSNPPESSSVSMKSDQSTLEPEKVDGGHTSTGISSQRSNPPKPMPRSIKSDQSTPELDKVDGGHTSTALSSQRSNPPDPKPRSIKSDQSTPEPDKVDGGHTSTGLSSQRSNPPESSSVSMKSDQSTLEPDKVDGGHTSTGLSSQRSNPPESSSVSMKSDQSTLEPEKVDGGHTSTGIGCQRSNPPDPKPRSIKSDQSTLEPDKVDGGHTSTGLSSQRSNPPESSSVSMKSDQSTLEPDKVDGGHTSTGISSQRSNP------------------------------------------------PESSSVSMKSDQSTLEPEKVDGGHTS---TGISSQRSNPPESSLVSLKSDQSTLEPDKVDGGHTSTGI------SSQRSNPPESSSVSMKS-DQSMPEPIKFDGGHTPTGLSETSTNDQFMNKQVKIKRRHTLTGLSKTSINYQFMEKQLKTERRHTSTGLSLNSKLFENLLKSNLLKKFQCVSEGTSILGNPTLLNEIYTELYITESDSGEINNEHELRQIETQSRRSAKEDTPIQCRDIFTPLPG---------QDKAIRTVLTKGVAGIGKTVSVQKFIVDWAEKNKNQD-IQLIFPLPFREINLMKD-RTLSLSDLLQVFFPETKEMEI--SSEHYKVLFIFDGLDECRVSLDFDSGVKLHDVSESASVDVLLMNLIMGNLLPSALIWITSRPAAADLIPSGFVH-RVTEVRGFNDPQKEEYFRKRIRDQSLADTIISHLKSSRSLHIMCHIPVFCWISATVLEKIFS----------------QAERGE----IPKTLTQMYTHFLIMQTNIRHEKDYE----EE--DKD----MILKLGKLAFEQLQKGNLIFYEEDLRECGLDLTEAAVYSGLCTQIFREEFGFSQSKVFCFVHLSIQEHLAALYAHHFLTNNCLN--------------------------------------------KHWKTFNPLSFLHQRAVNEALQSKNGHLDLFLRFLLGLSLEFNQTLLQELLTQTGSCSYNTEETVQFIKQKIR--EINSPERSINLFHCLNELGDQSLMK-------EIQNYLRSG---EIKETKLSSSQWSALVYVLLTSEQEMEDFDLNQFIG---------TQNTADEVLQKLQPVVKESRSVQLSGCSVTDKGCAALALVLRSDSSHLRELDLSENNLRDS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GVKLLSDGLKDPHCKLEKLRLS-------------------------------------------------------------------DCGVTDEGCAALASALRSNSTHLTELDLSLNNLEDSGVKLLSDGLKDPHCKLEILRLSDCGVTVEGCADLASALRSNST----------------HLRELDLTLNNLEDSGVNLLSAGLKDPHCKLE--------------------------------------------------------------------------------------------------KLRLSDCGFTDEGCA---------------------------------DLASALRSN-------------STHLTELDLSLNNFGDSG----------------------------------------------VKLLSDGLK---DPHCKLEKLRLSYCR-------------VRAEGGVALASALRSNPEHLRELDLSENKL--------------------------------------------------------------------------------------------------------------------GNSGVKMLSELKNDSR------------YKLDTLKF-------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M6YU37-1", "uniprot_id": "A0A8M6YU37_DANRE", "id": "A0A8M6YU37-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEDNQ----------TFSDAPVCSNESNPE-----------------------------------------------FEPSCVSMKSDQSMDPPMKFKEGHTS---ADLS-DRLNPPGSSCVSMKSDWSMDRPIQFKEEHSSADL------SN-KSNPGEPSCVSSKS-DQSMGPPIN--------------------------------------------------VMEEHSAADLRLDPHLKQNGLRSNLLRKFQCLYEGTAMQGDPTLLNEIYTELYITESDSGEINNKHELRQIETRSRRSATEDTPIQCRDIFTPLPG---------QDKAIRTVLTKGVAGIGKTVSVQKFIVDWAEEKENQD-IQLIFPLPFREINLMKD-RTLSLSDLLQVFFPETKEMEI--SSEQFKVLFIFDGLDECRVSLDFKCDVKLHDVSESASVDVLLTNLIMGNLLPSALIWITSRPAAADLIPSEFVH-RVTEIRGFNDPQKEEYFRKRIRDQFLADIIIINLKSSRSLHIMCHIPVFCWISATVLEKIFS----------------QAQSGE----IPKTLTQMYTHFLIMQTNIRHEKDYE----EEVRDED----MILKLGKLAFEQLVKGNLIFYEEDLRECGLDVTEASVYSGLCTQIFREEFGFYQGKVFCFVHLSIQEHLAALYAHHSLTNKNRNVFKQTKPS-------------------------------LLSKVLNQKKHDSLSVLHQRAVKEASQSKNGHLDLFLRFLLGLSLESSGTLLRELLTQTGSCSYNKEETVQYIKQKIR--ENRSPERSINLFHCLNELGEDSLMQ-------EIQDYLSSG---EIKETKLSSSQWSALVYVLLTSEKKMDFFDLSKFIG---------PQLRADVVLQKLLPVVKESRSVRLGDCKVTDKVCAALASALRLNSSHLTQLDLIGNKLGDS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GVKLLSDGLKDPHCKLKNLMMR-------------------------------------------------------------------DCGVTDEGCAALASALRSNSTHLTELNLNENNLGDAGVKRLSDGLKGPHCKLEILRLWRCGVRDEGCAALASALSSNST----------------HLKELELSDNKLGDSGVKLLSDALKDPHCKLE--------------------------------------------------------------------------------------------------KLRLNGCGVREQGCV---------------------------------SLALALRFNP------------SSHLTELDLTSNELGKSG----------------------------------------------VKLLSDLRD---DPRYKLRHL----------------------------------------ACDMFGRII--------------------------------------------------------------------------------------------------------------------VSSGGGRLDELLPTTS------------TET------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8N7UUW9-1", "uniprot_id": "A0A8N7UUW9_DANRE", "id": "A0A8N7UUW9-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDHRGHRDENLPKGRP-----------------------TFPHRSNPPEPSGVSMKSDRS------MHHPLKFKGNTGFRVKP------------------------------------------------PEPSGVSMKSDRSMHHPLKFKGGID-------PGFRVNPPEPSGVSMKSDWSMHHPLKFSGGIDP------------MFRPPEPS-VSEKS-GQSVDPTLK---------------------------------------------------FSVHTCHGSSHRKPLQT--FRSNLLKKFQCVSEGTARNKSPTLLNEIYTELYITEGDSGEINNEHEVRQIETQSRRSTTEDTPIQCRDIFTALPG---------QHKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQD-VQLIFPLPFREINLMKD-RTLSLADLLHVFFPETKEMEI--SRDGYKVLFIFDGLDECRLSLDFNSGVKLCDISESASVEDLLINLIVGNLLPSALIWITSRPAAADLIPSAFVH-RLTEVRGFTDPQKEEYFRKRIRDQRLADEIIQHLKSCRSLFIMCHIPVFCWISATVLEDMMR----------------RTDIGE----IPKTLTEMYTHFLIIQTSIRHEKHYE----KKLKDEE----MILKLGKLAFRQLMKGNLIFYEEDLRECGIDESEASVYSGLCTQIFREELGLFQGKVFCFVHLSIQEHLAALYVLLSFLLYERDELSEN----------------------------------FRSTRPHEFTCHTVFDLHQRAVDKALQSRNGHLDLFLRFLLGLSLKSNQTLLKNVLTQVGNISYSQEETVEYIKIRIK--LNPSPEKSINLFHCLNELGDHSLVN-------EVQKYVRSG---DLSGSRLSSSQWSAVVFILLTSEQ-LDEFNLRRYLTDSEHQTQTQKLQTPDEVLQKLLSVVEASRSAVLINCGVSDEGCAALASVLRSKSSNLRELNLSENKVGDS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GVKRLSAGLKDPHCKLEKLRLR-------------------------------------------------------------------CCGVSDEGCAALASVLKSNSSNLRELDLSWNKVGDSGVKLLSAGLKDPHCKLEKLRLCRCGVSDEGCAALVSVLSSNSS----------------NLRELNLTENKVGDSGVKLLSAGLKE-NSKLE--------------------------------------------------------------------------------------------------KLWLFICGVSDEGCA---------------------------------ALASILRSN-------------SSNLRELDLTGNKVGDSG----------------------------------------------VKLLSAGLK---DPHCKLEKLTLDFCG-------------VSDEGCAALASALRSNSSNLRELNLFNNNL--------------------------------------------------------------------------------------------------------------------GVSGVKLLSDLRDDPH------------YKLETLHISWGFIC-------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M6Z1F5-1", "uniprot_id": "A0A8M6Z1F5_DANRE", "id": "A0A8M6Z1F5-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------METE--GPDSPEPSCVSLRSDHSK------------------------------------------------------------------------AHHVLFKDEDPFEYS--------------SGQTGRSSPTPSHVSLASNMSINQP-------------------------------------------------------------------------------------------------LEFKSCSNTLLLKEIQEAIQSVLRIRFQCLHEGLSKHSVLIPLNDIYTELYITEGEGGELNNEHEIRWIETACRRALTEDRPVNLNDIFKPLHG---------QDRPIRTVLTKGVAGIGKTVSVQKFIIDWAEGEANQD-IWFIFPLPFRELNLLKD-QSFSLKGLLQYFMN--IELDI--SLHEGKIMFIFDGLDECRLPLDFHNNVKLCDVTESASVDVLLTNIIRGNLLPSSLIWITSRPAAADVVPSKCIH-RVTEVRGFSDPQKEEYIRKKVSDQTLSDRIISHLKSSRSLYIMCHIPVFCWISATVLKKMLS----------------EAESAE----IPNTLTQMYTQFLMLQLRIKNEKAYD----KKSSDID----IVLKLGELAFQQLEKLNLIFYKEDLREYGIDEQEASVYSG----LFREESGMFQGKVYSFVHLSVQEHLAALYVYLYFVNENINKLNQPNF-----------------------------------LTSILKCVPTVFDVYQTAVKKALQSTSGHLDLFLRFLLGFSLESNQNLLGDLQVQTESSSDSREQIVGFIKEKIK--ESPPPEKMINLFHCLNELNDHSLVE-------EIQDFLQSE--SRIN-MKLTASQWSAMVFVLLTSGQKLDVFDLNKYIGT---------YILPDESLQRLQPVLAASRTAKLCEHNLTKRGYSVLVSVLTSKTSCLRELNLTRSAVNDSGLKLLCSGLENPQCKLETLRLEFCGVSDKGCDFLASALRSNPSHLKALDLSGNTLNFTGLKNLLAEFQKPHCKLQRLCLRLCG----------------------------------------------------------LTDVGCDALASVLRSDPSHLTELNLSGNKLGDLGMKLLAGGLQNPHCKLQILRLG-------------------------------------------------------------------DCSITHEGCAALASALRSNPSHLRELDLSGNKLNNAGVQILSGELENPDCNLEILRLENCDVGEEGCAALAEALKSNPL----------------TLKELDLCWNKLGNSGVQRLCTSLENPNCTLG--------------------------------------------------------------------------------------------------VLRLTGCNISENGCA---------------------------------ALASVLRSN-------------PSYLRDLDLSHNDLRSSG----------------------------------------------VRLLSSALE---KPDCKLEILRLEYCK-------------ITDDGCAVLASALKSNPSHLRELYLYMN---------------------------------------------------SFNLTAS---------------------------------------------------------------GRQLLSKIKDDPH------------YKLQTLHYESHFFC-------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3ANC0-1", "uniprot_id": "A0A8M3ANC0_DANRE", "id": "A0A8M3ANC0-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDSRKRRSSSPESSCVSIKSDASMDNPPTLRLGESPAKHRRSSSLG--------------------------------------------------SSCVSMKSDASMDNPPTLRLGESP-----AKHRRSSSPESSCVSMKSDASMDNPPTLRLGESPAKHSDNQKRSQSNKGQKQLDAIFKDLEETNIDEMRKVLRRFKMLLSPDYSVRDE--------EEEEGQRQINEAFLKITLHALQKMNQTDLASKLQTKLISVSQQQLKSRLKQRFERFTEGVSNRGNTKLLNDIYTEVYITEGGAGNIDDEHEVRQIETSSSRFP--EIPIRCCDIFKSLLG---------QDKAIRTVLTKGVAGIGKTASVQKFILDWAEGKANQD-VHFIFPLPFRDLNLIKE-KRMSLMELLCCFCP--ELKPI--DYNNFKTVFIYDGLDEWRLPLDFRNNEILWDMNKVASVDALLTNLLQGNLLPSAVHWITTRPAAACQIPAEFID-RVTEVRGFKDLQRAEYFWKRIKDQNLANKIITHIQSSRSLHIMCRIPVFCWISATVLEKIFG----------------EANSAD----IPKTLTQMFIHLLIVQTNLKTQKYDR----ECDVNLEKARKSILSLAKLAFEQLEKGNLIFYEEDLKQCGIDVREASVCSGVCTQIFREEFGLQLQKVFSFVHLSVQEFLAALFKFLSFAEE-----NNKSS-----------------------------------MTQFMK----------NEVDRALQSPNGHLDLFLRFLLGLSLDSNQTLLQGLFTPLDTS-HSRDETIEYIKSKIR--ENPSPERSINLFYCLNELNDHSLVQ-------EVQTYLTSTRSHRLSGVKLSPALWSALVFVLLNSTKDLDEFELRQYD-------------FTEECLLRLLPVVKASRKADLKGGNLTDQICSALASALSSSSCCLRELDLSENRLQLSGIRLFSAGLKSPNCKLEILKLSNCSIREEGCASLVSALLSNPSHLRELNLNSNQPGYSTVKLLSDLLENPHCKLEKLQLYNCC----------------------------------------------------------IGEEGCAALALALISNPSHLRELNLNNNEPGDSGVKLLSDLLKDPRCKLEKLQLNGSNIREK---------DCAAFISSLLSNPFHLRELSLSWNKPGDSGVKLLSDLLKDSRCKLEKLELECCSIIEEGCAALALALVSNPSHLRELNLNNNEPGDLGVNLLSFLLKNPQCKLEKLELEYCCIGAKSCASLASAFVSNPS----------------HLRELNLNWNTPEYPAVKLLSDYLKDPHCKLE--------------------------------------------------------------------------------------------------KLQLYNCCIGEEGCA---------------------------------ALALALISN-------------PSHLRELNLNNNEPGDSG----------------------------------------------VKLLSDLLK---DPRCKLEKLQLEYCC-------------IGEEGCAALVSGLKSNPSHLRELNLNRNEPGNLGAKMLSDLLKDPLFELEKLELDDCSIENNGFADLVSGLKSNPSNIRELNLNSNKFIFSGLNLLCDLLRDQQCKLRKLQLECCNIDEEGCAALALALISNPSHLRELNLNYNNPGGLGVKLLSVLLKNPH------------CKLEKLELSHCSISENYLAALNSALSSNPAHLRELNLNYNENTRQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M6Z5L8-1", "uniprot_id": "A0A8M6Z5L8_DANRE", "id": "A0A8M6Z5L8-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKDFNENRSRITDAALDLTLFFLRE---------------------------------------MKQDQAADTLQGELFFINQLKCSLKKKYQSVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNTDHEIRQIEAASRRHQSLEIQVECKHLFEAAE----------QHEQIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQD-ISFIFPLPFREMNLKEK-ERQSLKDLITQFFPETEGLNL-TRSTRFKVLFILDGLDECRLPLNFAGNETCRDVSSAVSLDVLLTNLIKGNLLPSALIWITSRPAAASKIPADCID-RLTEIRGFNDAQKEEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVFCWISATVLQNILK------LKHRAH---AETLQES-----PKTLTQMYTHFLRFQIQQSRRKYDG----ENTADVSWDPNLILSLGKLAFQQLERNNVIFYESDLKDCGIDVDKASVYSGMCTQIFKEETGIILGTMYCFLHLSIQEFIAALYQHLILDNDKKQG----------------------------------------WFFIQISKNKGMIDFLKTAVDKALESENGHLDLYLRFLLGLSLQSNRQLLRGLLTQQDDRDQSKGEIIAYIKQKL--EGNLSPERSINLFYCLNELNDQTLLK-------QIQSHLSRG---SLSSADLSPAQWSALVFVLLTSEEELEVFELQKFQRS-------------DECLIRLSAVIKTSKRALLQGCYLTVRSCESLSSALQSSNCVLRELDLSNNDLQDSGVKKLSDGLKSQHCKLETLRLQFCNLTVQCCESLSSALQS--------------------------------------------------------------------------------------------------------------------SNCVLRELDLSINDLQDSGVKKLSDGLKSQHCKLDTLR-------------------------------------------------------------------LSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGGE---------TRITAGP-----------------RKYVCFLTLDPNTAHTELILSEENREVKSVRE-------NQPYPD------HPDRFD------------------------------------------------------------------YYHQVLCRESVCGRCYWEIDWS----------------------------GDGVVCISVSYKS----IRRKGGG---DECVFGYNAQSWSLRCD-----------------------------------------------SSRFKFWHN---NTHTDLP-VEALSSR-------------IGVFVDHSAGILIFYNIYR-DTMSLIHS------------------------------------------------------------------------------------------------------------------------VQTTFTEPLCA---GFR-------VYYPGSSVKLS------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32TJY6-1", "uniprot_id": "A0AB32TJY6_DANRE", "id": "A0AB32TJY6-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSQQIQETRLKGDTRASQTISSPSSSCSMAEERVKD---------------------------------------------SLSEKHSVRSGSCVSSSVSLKSDRSKDCP-PVFSGETPSSAQSVEFESADSGDETHRRHKSFTDNLQSIFQNLESKMFTFLKNELEKFKKILQE-NRQEIVKEFNENRSRITEAALDLTIFFLRE---------------------------------------MKQDQAADTLVGELFFINQLKCSLKKKYQSVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNTEHEIRQIEAASRRHQSLEIQVKCKHLFEAAE----------QDEQIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQD-ISFIFPLPFREMNLMEK-ERQSLKDLITQFFPETKGLNL-TRSTRFKVLFILDGLDECRLPLNFAGNETCRDVSSAVSLDVLLTNLIKGNLLPSALIWITSRPAAASKIPADCID-RLTEIRGFNDDQKQEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVFCWISATVLQNILK------LKHRAH---AETLQES-----PKTLTQMYTHFLRFQIQQSRRKYDG----ENTADVSWDPKLILSLGKLAFQQLERNNVIFYESDLKDCGIDVYKASVYSGMCTQIFKKETGFVLHTMYCFLHLSIQEFIAALYQHLILDNDKTQ--------------------------------------------AEKSRDESMIDLLKAAVDKALESENGHLDLYLRFLLGLSLQSNRQLLRGLLTQQDDRDQSKEEIIAYIKQKL--EANLSPERSINLFYCLNELNDQSLLK-------QIQSHLSSG---SLSSARLSPAQWSALVFVLLTSEEELEEFELQKFQRS-------------DECLIRLSAIIKTSKRALLQGCYLTVPSCESLSSVLQSSNCVLRGLDLSNNDLQDSGVNLLSDGLKSQHCKLETLRLVMCNLTVESCESLSSVLQS--------------------------------------------------------------------------------------------------------------------SNFVLRELDLSNNDLQDSGVKLLSDGLKTVNCKLETLR-------------------------------------------------------------------LSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVELLFEKLADPNYTLDKLNLDHGGH---------TRITAGP-----------------RKNACFLTLDPNTTYAFLILSEENREVKTVRE-------YQLYPD------HPDRFDG-----------------------------------------------------------------IYPQVLCRESVCGRCYWEIDWS----------------------------GDDYVDISVSYKS----IMRKGVD---PECVFGRNAQSWSLCCD-----------------------------------------------SSSFTFWHN---DTDTRLP-VKPLSRR-------------IGVFVDHSAGTLIFYNIYR-DTMSLIHS------------------------------------------------------------------------------------------------------------------------VQTTFTEPLWP---GFT-------VWCQ-SSVKLC------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M6Z047-1", "uniprot_id": "A0A8M6Z047_DANRE", "id": "A0A8M6Z047-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAEERVKDSLS-EKHRVRSGSCVSSSVSLKSDCSKEDPPK-------------------------------------FSEKTPSSAQSVRSGLCVSSFVSLKSDCSKEDP-PKFSEKTPSSAQSDEDELPDSGQETHRNHKSFTDNLQSIFQNLESKMFRFLKNELEKFKQILQEENRQEFVKDYNENRSRITEAALDLTLFFLRE---------------------------------------MKQDHAADTLQDELLFINQLKCSLKKKYQSVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNTEHEIRQIEAVSRRHQSLETQVEFKHLFKAE-----------QDEQIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQD-ISFIFPLPFREMNLKEK-ERQSLKDLITQLFPETKGLNL-TRSTQFKVLFILDGLDECRLPPNFAGNEMCCDVSSAVSLDVLLTNLIKGNLLPSALIWITSRPAAASKIPADCID-RLTEIRGFNDAQKEEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVFCWISATVLQNILN------LKHRAH---AETLQES-----PKTLTQMYTHFLRFQIQQSRRKYDG----ENTADVSWDPKLILSQGKLAFQQLERNNVIFYESDLNDCGIDVYKASVYSGMCTQIFKKETGIILGTMYCFLHLSIQEFIAALYQHLILDNNKKQ--------------------------------------------AEKSRNESMINLLKTAVDKALESENGHLDLYLRFLLGLSLQSNRQLLRGLLTQQDDRDQSKEGIIAYIKQKL--EGNLSPERSINLFYCLSELNDQTLLK-------EIQSHLSRG---SLSSARLSPAQWSALVFVLLTSEEELEEFELWKFQRS-------------DECLIRLSAIIKNSKRALLQSCNLTVQSCKSLSSILQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSQHCKLDTLRLATCNLTVQCCESLSSVLQS--------------------------------------------------------------------------------------------------------------------SNCVLRELDLSNNDLQDSGVKKLSDGLKSEHCKLDTLR-------------------------------------------------------------------LSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEKWQCPNYTLDTLNLDHVGD---------MRITAGP-----------------RKYVCFLTLDPNTANTQLKLSKENRKVKHVREDLRIMRKDRRYPY------HPDRFDP-----------------------------------------------------------------VF-QVLCRESVCGRCYWEIDWS----------------------------GDHGVFISVSYKS----IRRKR-G---DACEFGCNAQSWSLLCL-----------------------------------------------SSRFTFRHN---NTHTHVP-VKPLSRR-------------IGVFVDHSAGTLIFYNIYK-DTMSLIHS------------------------------------------------------------------------------------------------------------------------VQTTFTEPLCP---GFG-------FYSG-SSVKLS------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32TMV3-1", "uniprot_id": "A0AB32TMV3_DANRE", "id": "A0AB32TMV3-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAEERVKDSLS-EKHSVRSGSCVSSSVSLKSDWSKEDPPK-------------------------------------FSEKTPSSAQSVRSGSCVSSSVSLKSDRSKEHPLPNFREKTPSSAQSVEHELPDSGQETHRNHKSFTDNLQSIFQNLESKMFRFLKNEMEKFKKILQEENRQEFVKDYNENRSRITEAALDLTLFFLRE---------------------------------------IKQDQAADTLQDELFSINQFQCSLKKKYQSVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNNEHEIRQLEAASRRHQSLETQVECKHLFEAAE----------QDEQIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQD-ISFIFPLPFREMNLKEK-ERQSLKDLITQFFPETKGLNL-TRSTRFKVLFILDGLDECRLPLNFAGNKTCRDVSSAVSLDVLLTNLIKGNLLPSALIWITSRPAAANKIPADCID-RLTEIRGFNDAQKEEYFRKRLTDQNQAREIIDHIKQSKILFIMCHIPVFCWISATVLQNILK------LKHRAH---AETLQES-----PKTLTQMYTHFLRFQIQQSRRKYDG----ENTADVSWDPKLILSLGKLAFQQLERNNVIFYESDLKDCGIDVYKASVYSGMCTQIFKKETGIILGTMYCFLHLSIQEFIAALYQHLILDNNKKQ--------------------------------------------AEKSRNESMINLLKTAVDKALENENGHLDLYLRFLLGLSLQSNRQLLRGLLTQQDDRDESKKKIIAYIKQKL--EGNLSPERSINLFYCLNELNDQTLLK-------EIQSHLSRG---SLSSARLSPAQWSALVFMLLTSEEELEEFELRKFQRS-------------DECLIRLSAVIKTSKKALLQSCNVTVQSCKSLSKVLQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSQHCKLETLRLAMCNLTVQCCESLSLALQS--------------------------------------------------------------------------------------------------------------------SNCVLRELDLSNNDLQDSGVKLLSNRLKSQYCKLETLR-------------------------------------------------------------------LSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEKWQCPNYTLDKLNLDHGGE---------KRITAGL-----------------HKYVCFLTLDPNTAHIQLILSEENRKVKPVREDMMMMRKDQPYPD------HPDRFDG-----------------------------------------------------------------LYPQVLCRESVCGCCYWETDWS----------------------------GDGGVCISVSYKS----IRRKG-G---VECEFGRNAQSWSLHCS-----------------------------------------------SSRFIFIHN---NTETRLP-VKRLSKR-------------IGVFVDHSAGTLIFYNIYR-DTMSLIHS------------------------------------------------------------------------------------------------------------------------VQTTFTEPLCP---GFR-------VYSG-SSVKLS------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32TQA8-1", "uniprot_id": "A0AB32TQA8_DANRE", "id": "A0AB32TQA8-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAEEQVKDSLS-EKQSVRSGSCVSSSVSLKSDNSKG-----------------------------------------------GRTPNFRGKTPSSVKRFFHLGKSKHPP-SNLREKTPSSAESFQYELPDSRNKTHRSQKSFRGHLQKIFENLESKIIKFVKKELKNFRKILQNENRQEFVKEFNENSSGITEAALDLTLFFLRE---------------------------------------MKQDQAADTLQGELLYINQLKCSLKKKYQSVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNTEHEIRQIEAASRRHQSLEIQVECKHLFEAAE----------QDEQIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQD-ISFIFPLPFREMNLKEK-ERQSLKDLITQFFPETKGLNL-TRSTRFKVLFILDGLDECRLPLNFAGNETCRDVSSVVSLDVLLTNLIKGNLLPSALIWITSRPAAASKIPADCID-RLTEIRGFNDTQKEEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVLCWISATVLQNILK------LKHRAH---AETLQES-----PKTLTQMYTHFLRFQIQQSRRKYDG----ENTADVSWDPNLILSLGKLAFQQLERNNVIFYESDLKDCGIDVYKASVYSGMCTQIFKEETGIILGTMYCFLHLSIQEFIAALYQHLILDNNKKQ--------------------------------------------AEKSRNKVMINLLKTAVDKALESENGHLDLYLRFLLSLSLQSNRQLLRGLLTQQDDRDQSKEEIIAYIKQKL--EGNLSPERSINLFYCLNELNDQTLLK-------QIQSHLSRG---SLSSARLSPAQWSALVFVLLTSEEELEEFELQKFQRS-------------DECLIRLSAVIKTSKRALLQ----------------------------------------------------------CCNLTVQCCESISSVLQS--------------------------------------------------------------------------------------------------------------------SNCVLRELDLSNNDLQDSGVKKLSDGLKSQQCKLETLR-------------------------------------------------------------------LSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGGE---------KRITAGP-----------------HKYVCFLTLDPNTAHTRLILSEENREVKCVRE-------NQPYPD------HPHRFD------------------------------------------------------------------YYLQVLCRESVCGRCYWEIDWS----------------------------GDDGVCISVSYKS----IRRKRGG---AECAFGRNAQSWSLICS-----------------------------------------------SSSFTFRHN---NSHTDLT-VKPLSRR-------------IGVFVDHSAGTLIFYDIYR-DTMSLIHS------------------------------------------------------------------------------------------------------------------------VQTTFTEPLCP---GFY-------VSYG-SSVKLS------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32TPE7-1", "uniprot_id": "A0AB32TPE7_DANRE", "id": "A0AB32TPE7-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAEERVKDSLS-EKYSVRSGS--------------------------------------------------------------------------SSSVSLKSDWSKDEP-PKFSEKSPSSARSVEYELPYSGDKTHRSHKGFTKDLPRIFQNLESKIIRYLKNELEKFKKILQEENRQDFVKHFNENRSIITEAALDLTLFFLRE---------------------------------------MKQDEAADTLEGELFFINQLKCGLKKKYQNVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNTEHEIRQIEAASRRHQSLEIQVECKHLFEAAE----------QDEQIRTVLTTGVAGIGKSVSVQKFVLDWAEGKENQD-ISFIFPLPFREMNLMEK-ENQSLKDLITQFFPQTKGLNL-TRSTRFKVLFILDGLDECRLPLNFAGNETCRDVSSAVSLDVLLTKLIKGNLLPSALIWITSRPAAANKIPADCID-RLTEIRGFNDAQKEEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVFCWISANVLLNILKENRNTELKHRDN---SETLHES-----PKTLTQMYTHFLRFQIQHSRRKYDG----ENTADVSWDPNLILSLGKLAFQQLERNNVIFYDSDLKDCGIDVYKASVYSGMCTQIFWEETGIILGTMYCFLHLSIQEFIAALYQHLFLDSDKKHL----------------------------------------SIFRQKSKNKVMTDLLKTAVDKALESENGHLDLYLRFLLGLSLQSNRQLLRGLLTQQNDRDQSKEEIIAYIKQKL--EGNLSPERSINLFYCLNELNDQTLLK-------EIQSHLSSG---SLSSADLSPAQWSAVAFVLLTSEEELEEFELQKFQRS-------------DECLIRLSAVIKTSKRALLQG----------------------------------------------------------CNLNVRCCESLSSALQS--------------------------------------------------------------------------------------------------------------------SNCLLRELDLSNNDLQDSGVKLLSDGLKSQHCKLETLR-------------------------------------------------------------------LSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDTLNLNHGGE---------KRITAGP-----------------RKYVCFFTLDPNTANTRLILSKKNREVKCVRE-------NQSYPR------HPDRFD------------------------------------------------------------------DHPQVLCRESVCGRCYWEIDWS----------------------------GGNEVCISVTYKS----IRRKR-G---YECRFGYNAQSWSLICS-----------------------------------------------SSRFSFTHN---DTHTDLP-VKPFSRR-------------IGVFVDHCAGTLIFYNIYR-DTMSLIHS------------------------------------------------------------------------------------------------------------------------VQTTFTEPLIP---GFW-------VYSG-SSVKLLKTEERFTQNPLQDQ----------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32T552-1", "uniprot_id": "A0AB32T552_DANRE", "id": "A0AB32T552-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAEERVKDSLS-GKHSVRSGS------------------------------------------------------------------------CVSRSVSLKSDESRKGLPPEFSEQPPSSNRSVEYELSDSVDKTHCNRKSFTDHLLRIFQDLESKIFKVLKNELERFRQILQGENTQDFVKGSNENQSSITKSALDLTLLFLRE---------------------------------------MKQDEVADTLENELLFINRLKSSLKKTYQSVSEGIAQQGDSTLLNNIYTDLYITQGANEQVNTEHEIRQIEAASRCHKSLEIQVECKHLFEAPE----------QDKQIRTVLTKGVAGIGKSVSVQKFVVDWAEGKANQD-ISLIFPLPFREMNLKEK-EKQSLKDLITQLFPEVKGLNL-TRRTRNKVLFILDGLDECRLPLNFAGNETCHDVSAPAYLDVLLTNLIKGNLLPSALIWITSRPAAASKIPADCID-RLTEIRGFNDAQKEEYFRKRLADQNLAMEIIEHIKQSKSLHIMCHIPVFCWISATVLQNVLKET---KVKHKAC---AKTLQES-----PKTLTQMYTHFLRFQMQQSRQKYDG----KNTDGVSWDQNFILSLGKLAYQQLERNNVIFYESDLKDCGIDVYKASVYSGMCTQIFKQETGIILGNLYCFLHLSIQEFIAALYGHLYLDIKKKS-----------------------------------------VFTGQKHKNKGMTHLLKTAVDKALESDNGHLDLYLRFLLGLSLQTNRQLLRGLLTQQDKSDQSKEEIVVYIKQKL--EENLSPERAINLLYCLNELNDHSLMK-------EIQSHLRDG---SLSSADLSPAQWSALTFVLLTSEEELDEFDLQKFKKS-------------DECLIRLSAVIKSSKRALLQCCNLTAQSCESLSSALQSSNCVLRELELSNNDLQDSGVKLLSCGLRSLNCPLEILRLQCCNLTAQSCESLSLALQS--------------------------------------------------------------------------------------------------------------------STCVLRELDLSNNDLQDSGVKLISNGLKS--CKLEILR-------------------------------------------------------------------LSGCMVTETGCGFLSSALSSNPTHLRELDLSYNHPGVSGVKLLCQKLEDPNYTLAKLNVDHAGA---------KRITAGP-----------------RKWISHLTLDPNTANTELSLSAENREATRVIE-------KQPYPD------HPDRFD------------------------------------------------------------------YHPQVLCRESVCGPCYWEIDWS----------------------------GDVGACISVSYKS----VSSKG------NDEFGCNDQSWSLSCY-----------------------------------------------SSRFSYGHN---NRWTDLP-VKPISRR-------------IGVYVDHRAETLRFYNICG-NTVHLVHS------------------------------------------------------------------------------------------------------------------------VRTTFTQPLYA---GFK-------IYPG-SSVKLC------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58JCL0-1", "uniprot_id": "A0AC58JCL0_DANRE", "id": "A0AC58JCL0-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAEERVKDSLS-EKHSVRSGS------------------------------------------------------------------------CVSSSVSLKSDQSKDHP-PYFREETPSSAESVEYESADPGDETHRRHKSFTDNLQSIFQNLESKIIRFLKNELEKFKKILQEENRKEFIKEFIENRSIITEAALDLTLFFLRE---------------------------------------MKQDQAADTLQDELFFINQLKCSLKKKYQSVFEGIAQQGDSTLLNKIYTDLYITQGASEQLNTEHEIRQIEAASRRHQSLEIQVECKHLFEAAE----------QDERIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQD-ISFIFPLPFREMNLKEK-ERQSLKDLITQFFPETKGLNL-TRSTRFKVLFILDGLDECRLPLNFAGNETCGDVSSAVSLDVLLTNLIMGNLLPSALIWITSRPAAASKIPADCID-RLTEIRGFNDAQKEEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVFCWISATVLQNILR------LKHRAH---AETLQES-----PKTLTQMYTHFLRFQIQQSRRKYDG----ENTADVSWDPNLILSLGKLAFQQLDRNNVIFYESDLKDCGIDVYKASVYSGMCTQIFKEETGIILGTMYCFLHLSIQEFIAALYQHLDID--KKRG----------------------------------------WFLIQISKNKSMIDLLKTAVDKALESENGHLDLYLRFLLGLSLQSNRQLLRGLLTQQDDRDQSKEEIIAYIKQKL--EGNLSPERSINLFYCLNELNDQTLLK-------EIQSHLSSG---SLSSARLSPAQWSALVFVLLTSEEELEEFELQKFQRS-------------DECLIRLSAVIKTSKRALLQ----------------------------------------------------------FCNLTVQCCESLSSALQS--------------------------------------------------------------------------------------------------------------------SNCVLRELDLSNNDLQDSGVKLLSDGLKSQHCKLDTLR-------------------------------------------------------------------LSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGGH---------TRITAGP-----------------RKCRTTHTQTHTHTHTHIHTHTHTHTHIHTHTHTHTHTHTRAHTHTHTRGLQQDRANVGPHTYTHTHTHTHTYTYTHTHTHTHTHTHTHTRITAGPRKCRTTHTHTHTYTHTHTHTITHTHLHIHTHTCTHTHTCAHTHTHIHTHTLTHTRTYTHTHTHTLPLTHTHTHTLSHTHTHTHTNIHTHS----LTHTNIH---THSLTHTNKHTHSLSHAYTHACMHALSHLHTHTHALTHTHTHTHTHSLTHTHICTHKHTHTLSHSHKHSHTHT---HTHTHTH-THTQARAHLHKHTLSHTHTHIHIYTHTYKHTHILSHTHA-HTHTHTQARALTQTYSLTHTHTHTHKHTL---------------------------------------------------------------------------------------------SHTHTHIHHTHTQIHIH---SHK-------THTHARTHTLSLSLTHTHTHTHTHTHTHTHTHTHTHTQLWL------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9PSD3-1", "uniprot_id": "A0A8M9PSD3_DANRE", "id": "A0A8M9PSD3-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSEEQGKMSLS-EKHSVISDSCVSGSVSVKSDCSKDGDLPNFSVEKPMSAKSVISDSCVSGSVSVKSDCSKDGDLPNFSVEKQTSAKSVISDSCVSGSVFVKSDCSKDGDLPNFSEETPSSGKSFEHKTSDSDFQTHRKHKGFQDGLLGIFQDLENQIMNYLKHELEKFKKILQKENIIDFVKDFNENRCSIKEAALDLTLYFLRE---------------------------------------MKQEESADTLEDELIFIHQLKCGLQKKYQCVFEGIAQQGDSRLLKNIYTDLYITQGGSEQVNTEHEVRQIEVASRRHEAQELQVECRHLFEASE----------QDKQIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQE-ISFIFPLPFREMNLKEK-ETLSLMELITQFFPETKGLNL-TRRNRFKVLFILDGLDECRLPLNFAGNETCCDVSSPASLDVLLTNLIKGNLLPSALIWITSRPAAASKIPPDCID-RLTEIRGFNDAQKEEYFRKRLTDENQAKEIIDHVKQSKSLFIMCHIPVFCWISATVLQNILQEKRNNDVKHNQADDASKTLQESNTEDTPKTLTQMYTHFLRFQIQQSRRKYNG----EYTPDVSWDKDAILSLGKLAFHHLLNNNLIFYDTDLEACGIDVYKASVYSGMCTQIFKEETGIILGTMYCFVHLTLQEFIAALYAHLILDTNKKSV----------------------------------------FDQDSKKINESMIDLLKTAVDKALESDNGHLDLFLRFLLGLSLQSNRRILRGLLTPQDQDDQSTEKILQYIKQKF--DANLSPERSINLFYCLNELNEQTLVK-------EIQTHLSKG---SLSSADFSSAHWSALAFVLLTSDEEMEEFELQKFHKS-------------DECLIRLSAVIKTCKRALLNDCNLTDRSCSALATVLESDTS-LKELNMSNNNLQDSGVKLLCTGLKDMKCELEILRLSDCNITEEGYKALASALRS--------------------------------------------------------------------------------------------------------------------NPSHLLELDLRGNDPGESGVKELDDLLQDPNCTLKTLRFLSPSAEESCQFVNGVVGKNPLLLKTLNLNDFRSTRNHPFIYEIEDTQVNHLAALLQDKHCRVNMLILGGCSFTDDQWESLTSALKLNPSHLRELILMWNGPGESGVKILSDFLIEPQLKLEKLCLCYCSITEERCEILTSALKSNPSHLRELNLSQNIPGDSGMKNLSDLLMNPQSKLEKLQLCKCSITEEQCVILTSALKSNPSHLRDLN--LSLNNLGD-------------------------------------------------------------SGVKTLSDLLMKPHLKMEKLWLCKCS--------------------------ITEEQCVILASALKSNPSHLRELSLS---ENNLGDSGVKNLSDLLMKP------------------------------------------QFKLEKLHLSHCSITEEQCEIL-TSALKSNPSHLR-----ELDISKNQIRNTGVNLLCDVLN-NSDCKLETLRLNDCG-----------------------------------------------------------------------------------------------------------ITDVSSLTQCLTNTKAL---QFLKVLYLRENHIGDSKQELSDVVRDSNCELSVDEFSLPDFGQIKDIKCCIS-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58JCK2-1", "uniprot_id": "A0AC58JCK2_DANRE", "id": "A0AC58JCK2-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAGYVFVLSSLCPVFILLQFLLEFLLEIKLFRSIMGNTHAAGDQDLSTECSSVHQKRAEAEPSCVSMKSDASMGVPITFKSENTGPAVSSVHQKRAEAELSCVSMKSDASMNPPIEFKSGNTGPAVSVDRDGQTGDLQQ---------------------------------------DSLQPEHDELQ---RVKEQHKTSMKNKYERLFEGINHGETQTLLNRIYTQLYIIEGESEGVNEEHEVLQMEKRARTKPSQHTPVYCNDIFKASAGAGHEEQIKKEKAQIKTVLTKGIAGIGKTVSVQKFILDWAEGKDNQD-VDFMFVLPFRELNLIRD-HQYSLHRLLLDFHPKLEDLEP-KIYEQCRVVFIFDGLDESRITLNFSDEEKVCAVTEPSSVAVLMRSLLKGDLLPSALIWITSRPAAAHQIPSTYIK-RLTEIQGFTEPQKEEYFRKRISDEHQASRIISHIRRARSLQIMCHIPVFCWISSTVLQKLLE----------------EDVSAE----IPQTLTEMYIHFLLIQINMRKQKYEE---RDPEKLLQSNRGVILKLAEVAFRQLMKGNVMFYEEDLIESGIDVTDASVYSGICTEIFKEESVIHQRKVYSFIHLSFQEFLAAFFVFYCHLTENREPLRVIYDSEYSYN-----------------------------QYLQSSSEKSLYDLLSSAVVKAVWSSNGHLDLFLRFLLGVSLDSNQRLFQDLLTHTEESSENIRRITQYIKDEIKRGKHLSAERSINLFLCLLEVKDQTLAR-------EIQEFVKSD---KHSEEELTPAHCSTISYMIEMSEEPLDELDSNKFNTS-------------DVGRRRLIAAVRNCRRALLQRCELTVQCCESLSSALQSSNCVLRELDLSNNDLQDSAVKLLSDGLKSQHCKLETLRLMTCKLTADSCESLSSALQSSNCVLRELDLSNNDLPDSGVKLLSDGLKSQHCKLETLRLQWCKLTVQCCESLSSVLQSSNCVLRELDLSNNDLQDSGVKKLSDGLKSQHCKLETLRLAMCNLTVQCCESLSSALQSSNCVLRELDLSNNDLQDSGVKLLSDGLKTVDCKLETLR-------------------------------------------------------------------LSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGGH---------TRITAGP-----------------RKYVCFLTLDPNTANTRLILSEENREVKHVRE-------NQPYPD------HPDRFDG-----------------------------------------------------------------VY-QVLCRESVCGRCYWEIDWSGDDG----------------------------VCISVSYKS----IRRKRGG---VECWFGSNAQSWSLSCSS-----------------------------------------------SNFSFRHN---NTRTDLP-VKALNRR-------------IGVFVDHSAGTLIFYNIYR-DTMSLIHS------------------------------------------------------------------------------------------------------------------------VQTTFTEPLCP---GFR--------IYPGSSVKLS------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32TQ28-1", "uniprot_id": "A0AB32TQ28_DANRE", "id": "A0AB32TQ28-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEDTHTSGDLDLFTSCS----------------------------------------------------------------------------VDGDDQTRDLQQ---------------------------------------DSLQPEHDELQ---RAKNQHKTSMKNKYERLFEGINHGETQKFLNRIYTQLYIIEGESEGVNREHDVLQIEKRARTKPSQHTPVYCNDIFKASAGAGHEEKIKKEKAQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQG-VDFMFVLPFRELNLIRD-HQYSLHRLLLDFHPELEDLEP-KIYEQCRVVFIFDGLDESRITLNFSDEEKVCAVTESSSVAVLMWSLLKGDLLPSALIWITARPAAAHQIPSTYIH-RLTEIQGFTEPQKEEYFRKRISDEHQASRIISHIRRARSLQIMCHIPVFCWISSTVLQKLLE----------------EDVSAE----IPQTLTEMYIHFLLIQINMRKQKYEE---RDQEKLLQSNRGVILKLAEVAFRQLMKGNVMFYEEDLIESGIDVTDASVYSGICTEIFKEESVIHQRKVYSFIHLSFQEFLAAFFVFHCYLTDKREPVMLLYESKYSDDEDVSD---------------GNEYEDSDVQFLQSSSEFSLCHLLSLAIYKAVMSSNGHLDLFLWFLLGVSLESNQRLFQDLLTHTEESSESIRIITQDIKDKIKTDDDLSAERSINLFLCLLEVKDQTLAR-------EIQEFVKSD---KHSERELSPAHCSTISYMIEMSEEPLDELDFNKLNTS-------------PVGRWRLIPAVRNCRRALLQWSYLSVQYCESLFSALKSSNCVLRELDLSTNDLQDSGVKLLSDGLKSPNCKLETLRLQCCNLTAQSCESLTSALQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSPNCKLETLRLVMCNLTVQCCESLSLALQSSNCVLRELDLSNNGLQDSGVKLLSDGLKSQHCKLDTLRLVMCNLTVQSSESLSSALQSSNCVLRELDLSTNDLQDSGVKLLSDGLKSQHCKLETLR-------------------------------------------------------------------LSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGGH---------TRITAGL-----------------HKYACFLTLDPNTTYAFLILSEENREVKRVRE-------YQQYPD------HPDRFDG-----------------------------------------------------------------IYPQVLCRESVCGRCYWEIDWSGDGCS---------------------------VCTAVSYKS----IRRKGRG---AECLFGRNAQSWSLCCSS-----------------------------------------------SSFIFRHN---YTRTELP-VKPLSRR-------------IGVFVDHSAGTLIFYNIYR-DTMSLIHS------------------------------------------------------------------------------------------------------------------------VQTTFTEPLYP---GFT--------VWCQSSVKLC------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58JCJ8-1", "uniprot_id": "A0AC58JCJ8_DANRE", "id": "A0AC58JCJ8-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAEERVKDSLSEKHSVRSGSCVSSSVSLKSDRSKEEHLPNFREKTPPSAQS---VRSGSCVSSSVSLKSDWSKRDPPNFREKTPSSAKSSVHQKRAEAEPSCVSMKSDWSMNRPITFRSKITQPAISVDRDDQTGHLQQ---------------------------------------DSLQPEHDELQ---RVKEQHKTSMKNKYERLFEGINHGETQTLLNRIYTQLYIIEGESEGVNEEHEVLQMEKRARTKPSQHTPVYCNDIFKASAGAGHEEKIKKEKAQIKTVLTKGIAGIGKTVSAQKFILDWAEEKDHQD-VDFMFVLPFRELNLIRD-HQYSLHRLLLDFHPELEDLEP-KIYEQCRVVFIFDGLDESRITLNFSDEEKVCALTESSSVAVLMWSLLKGDLLPSALIWITSRPAAAHQIPSRYIK-RLTEIQGFTEPQKEEYFRKRISDEHQASRIISHIRRARSLQIMCHIPVFCWISSTVLQKLLE----------------EDVSAE----IPQTLTEMYIHFLLIQIHMRKQKYEE---RDPEKLLQSNRGVILKLAEVAFSQLMKGNVMFHEEDLTESGIDVTDASVYSGICTEIFKEESVIHQRKVYSFIHLSFQEFLAAFFVLYCHLTENREPLRVIYDSEYSYN-----------------------------QYLQSSSEKSLYDLLSSAVVKAVWSSNGHLDLFLRFLLGVSLESNQRLFQDLLTHTEESTESIRRITQHIKDKIKRDKRLSAERSINLFLCLLEVKDQTLAR-------EIQEFVKSD---KHSEEELSPAHCSTISYMIEMSEEPLDELDFNKLNTS-------------AEGRRRLTAAVRNCRRALLQGCNLTVQCCESLSSALQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSQHCKLETLRLQWCKPTVQSCESLSSALQSSNCVLRELDLSNNDLQDSGVKKLSDGLKSQHCKLETLRLVMCNLTVQCCESLSSALQSSNYVLRELDLSNNDLQDSGVKKLSDGLKSPNCKLETLRLVMCNLTVQCCESLSSALQSSNCVLRELDLSNNDLQDSGVKLLSDGLK-RNCKLDTLR-------------------------------------------------------------------LSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGGE---------TRITAGP-----------------RKWVCFLTLDPNTAHTQLILSEENREVKRVRE-------NQPYPY------HPDRFD------------------------------------------------------------------VHRQVLCRESVCGRCYWEIDWSGDVG----------------------------VCISVSYKS----IRRKGRG---VECWFGYNAQSWSLICSS-----------------------------------------------SRFSFRHN---HTDTDLP-VEPLSRR-------------IGVFVDHSAGTLIFYNIYR-DTMSLIHS------------------------------------------------------------------------------------------------------------------------VQTTFTEPLCP---GFT--------VYSGSSVKLS------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1PS14-1", "uniprot_id": "A0A8M1PS14_DANRE", "id": "A0A8M1PS14-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDNMLQ---RIKNQHKTSLKNKYERLFEGIEVKETGTHLNRIYTQLYILEGESEGVNEEHEVLQMEKTARTKHSQHTPIYCNDIFKE------------EKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQD-VDFMFVLPFRELNLIRD-HQYSLHRLLLDFHPELEDLEP-KIYEECKVVFIFDGLDESRITLMFSDAQKVCDVTETSSVAVLMSKLMKGELLPSALIWITSRPAAANQIPSKYIK-RLTEIQGFTEPQKEEYFRKRISEQHQASRIISHIRRARSLHIMCHIPVFCWISSTVLQKLLE----------------EDLSAE----IPQTLTEMYIHFLLIQINMRNQKYEE---RDPENLLQSNREVIVKLAEVAFRQLMKGNVMFYEEDLIESGIDVSDASVYSGICTEILKEESVIQQRKVYSFIHLSFQEFLAAFHVFYHHITCSTE-----------------------------------------------ASLDSLHDLQKRIINKSTESENGRLDLFLRFLLGVSLESNQRLFQDLLTHTEKRSESIRRSTQYIKEKIRDGHGLSTERSINLFLCLLEVKDQTLSR-------EIQEFVKSD---KQSEKKLSPAHCSTIAYMLQMSEEVLDELKLQKYNTS-------------DEGRRRLIPAVSNCTRALLAGCNLSAQDCEIVSSVLQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NCQLEILR-------------------------------------------------------------------LSGCMVTEEGCGFLSSALSSNPSHLRELNLSYNHPGQSGVQLLQHTLEDPHYTLQKLNLDHGGH---------FRITPGL-----------------RKYACVLTLDPNTAHTHLVLSEKNRQARNVTD-------PQPYPD------HPDRFK------------------------------------------------------------------NNEQVLCRETLTGRCYWEVKWSGSGH------------------------------IGVAYKA----IDRKS-G---LDSWFGLNENSWSLYSCD-----------------------------------------------TIYTVWHN---NKSADIIAPSACTNR-------------VGVYVDVPSGSLSFYSVTDTHTLTLIHT------------------------------------------------------------------------------------------------------------------------FNTTFTEELYT---GFG--------IYPEASVSLCQI----------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32TUF4-1", "uniprot_id": "A0AB32TUF4_DANRE", "id": "A0AB32TUF4-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MHHCGNEEVDREEKEKHGAEHS------------CVSMKSDQSMRNPIAFTDKAVTFDLRSVASSSSHFETHT---VQEKT------------------DKGLQT----------------------------------------------QIFETEELQ---RVKDQHKTSMRKKYELLSEGIKVKETGTQLNRIYTQLYIIEGESEGVNEEHEVLQMEKTARTKHSQHTPIYCNDIFKE------------EKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQD-VDFMFVLPFRELNLIRD-HQYSLHTLLLDFHPELEDLEP-KIYEECKVVFIFDGLDESRITLMFSDAQKVCDVTETSSVAVLMSKLMKGELLPSALIWITSRPAAANQIPSKYIK-RLTEIQGFTEPQKEEYFRKRISEQHQASRIISHIRRARSLHIMCHIPVFCWISSTVLQKLLE----------------EDLSAE----IPQTLTEMYIHFLLIQINMRNQKYEE---RDPEKLLQSNREVIVKLAEVAFRQLMKGNVMFYEEDLIESGVDVSDASVYSGICTEIFKEESVIQQRKVYSFIHLSVQEFLAAFYVFYYHVNTTMMGL---------------------------------------------KTFASLQKLLKGAVDDAIESKNGRLDLFLRFLLGVSLESNQRLFQDLLTHTEKSSESIRRSTQYIKEKIRDGHGLSTERSINLFLCLLEVKDQTLSR-------EIQEFVKSD---KQSEKKLSPAHCSTIAYMLQMSEEVLDELELQKYNTS-------------DEGRRRLIPAVSNCTRALLAGCNLSAQDCEIVSSVLQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NCRLEILR-------------------------------------------------------------------LSGCMVTEEGCGFLSSALSSNPSHLRELDLSYNHPGQSGVQLLQHTLEDPHYTLQKLNLDHGGH---------FRIKPGL-----------------KKYACFLTLDPNTAHVQIQLSEGNREARNVKD-------PQPYPD------HPDRFD------------------------------------------------------------------QQEQVLCRETLTGRCYWEVKWSGSGH------------------------------IGVAYKA----IDRKS-G---LDSWFGLNENSWSLYCCD-----------------------------------------------TNYTVWYN---NESADIIAPSARTNR-------------VGVYLDVSSGSLSFYTVSDANTLTLIHT------------------------------------------------------------------------------------------------------------------------FNTTFTEPLYT---GFG--------LYPESSVSLCQI----------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9QCS9-1", "uniprot_id": "A0A8M9QCS9_DANRE", "id": "A0A8M9QCS9-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSLQKKNEDEDEESASEMSYPPPESS------------CVSMKSDWSMVYPPDLSDASVTSDPNNSKRKGQHLEFKESSCVSVMS------------------NRSITPPEMKK---------------------------------------IGLKSEDNMLE---KIKNKHKTSMKHKYERLFEGVKLHENQTLLNRIYTQLYILEGESEGVNEEHEVLQMEKTARTKHSQHTPIYCNDIFKE------------EKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQD-VDFMFVLPFRELNLIRD-HQYSLHTLLLDFHPELEDLEP-KIYEECKVVFIFDGLDESRITLMFSDAQKVCDVTETSSVAVLMSKLMKGELLPSALIWITSRPAAANQIPSKYIK-RLTEIQGFTEPQKEEYFRKRISEQHQASRIISHIRRARSLHIMCHIPVFCWISSTVLQKLLE----------------EDLSAE----IPQTLTEMYIHFLLIQINMRNQKYEE---RDPEKLLQSNREVIVKLAEVAFRQLMKGNVMFYEEDLIESGVGVSDASVYSGICTEIFKEESVIQQRKVYSFTHLSIQEFLAAFYVFYYHITCSTE-----------------------------------------------ACFDSLHDLQRRAVDKAIESENGRLDLFLRFLLGVSLESNQRLFQDLLTHTEKSSESIRRSTQYIKEKIRDGHGLSTERSINLFLCLLEVKDQTLSR-------EIQEFVKSD---KQSEKKLSPAHCSTIAYMLQMSEEVLDELELQKYNTS-------------DEGRRRLIPAVSNCTRALLAGCNLSAQDCEIVSSVLQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NCQLEILR-------------------------------------------------------------------LSGCMVTEEGCGFLSSALSSNPSHLRELDLSYNHPGQSGVQLLQHTLEDPHYTLQKLNLDHGGH---------FRITSGL-----------------RKYACFLTLDPITAHTQLQLSEENRKASIVTD-------PQPYPD------HPDRFD------------------------------------------------------------------QQEQVLCRETLTGRCYWEVKWSGSGL------------------------------VAVAYKG----IGRKS-G---FDCCFGHNEHSWCLYCSD-----------------------------------------------EVYSVWDN---NKSVDVFGPSSRTNR-------------VGVYVDVPSGCLSFYSVSDTNTLTHIHT------------------------------------------------------------------------------------------------------------------------FNTTFTEELYA---GFK--------VYPGSSVSLCPVKPAEVPP---------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3B0M3-1", "uniprot_id": "A0A8M3B0M3_DANRE", "id": "A0A8M3B0M3-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MESD-EQHNDTLVQMGSSGNSGIN-------------ADLRAEKEATVIAPLLNGN--NITGPVTFNYCSNSAENEPQKYPKT-------------------ADKHTEKQDD---------------------------------------LKLQK----------ILETHRTYMKKKVDCILDCT--KENAEHFKAFYTELFIAEGDMQDVNQEHEILKIDDAFKKKKASLRSIRCKDIFAELK----------AKSEKNTVLTKGIAGIGKTVSVRKFILDWAEGQTNHD-IHCVFLLPFREINLMTN-EDFNLHEFLLKFYPELKELETSVLFQQCNLAFIFDGLDESRLPLNFK-SRTLNNVEERSSVDMLFTSLVKGNLLPSALVWVTSRPAAANQIPPRYVG-LFTEVQGFTDQQKEKYFRNRIADETQASKIISHIKTSRSLYIMCHIPVFCWITATVLQDILQ----------------RN-IES----IGTTLTEMYIHFLLIQMNMKSQKYDPEEEREYAKLLEANREVILKLAKLAFEQLKKENVVFYEQDLKDCGIDVN--VEFTGMIAEIFKVEHGLHEAKVFYFVHLSVQEFLAAVYVFFCFLNRNTHELTFFFESSQNTPR----------------------ELQFLFKKTFRKVK--FHDLIKRATDKAMRSKRGHLDLFLRFLLGISLESSQNLLKGLFSHVIDTTRSIKKISPHFKHLQ--NKNISCDCSVNLFFCLLELKDHSLYE-------EIQRSLNSD---RRPSKELSSSMCTVLTYIVLMSEKELDELNPKRFTSS-------------QENYRKLVPAVRCCRKALFNGCGLDEMSFQTISSALQSSDSYLTELELSNNHLQDSGVKLLSDGLKSSHCQLNILRLCGCGLTDQSCESLSSALQSSNSVLRELDMSNNMLKDSGVKLLAVALKSLNCKLERLRFSMCN----------------------------------------------------------LTAESCESLSSVVELSNSVLRELDLSNNDLQDSGVKLLSDGLKR-NCRLEILR-------------------------------------------------------------------LSGCMVTEVGCGFLSSALSSTTSTLRELDLSYNHPGDSGEKLLSDAHNQPNCR---LCVDHGGE---------FRLTTGL-----------------HKYARFFTLDPNTANARLILSEENRKVTCVRK-------KQPYPD------HPDRFE------------------------------------------------------------------GYLQVLCRESVCGRSYWEIEWTG-VV-----------------------------FISVSYSS----IGRMGSD---KECWFGFSNQSWSLFCSS-----------------------------------------------DRCSFTHS---STEIDLP-VKHTSSR-------------IGVYVDHSAGTLSFYSVSD--TVSLIHS------------------------------------------------------------------------------------------------------------------------VQTTFTQPLHP---GFY--------ISLGSSVKLC------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32TTK4-1", "uniprot_id": "A0AB32TTK4_DANRE", "id": "A0AB32TTK4-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEAMNRLMTDMLEELVEAELKQFTR---------QLWMGVKPGVDPIPRGKLENKDRQDVVDCMVQHYSKDAGKIAVQALRSI-------------------KQNERADRLE---------------------------------------LNLRKDDDFLG---EVLKKHKESIKASVD-VFEGK--KDNKTDINKVYTELFITEGDMTDVCKEHEVQKFDLALQMPRSEDKPIDCNEIFNLLR----------GKDKGNVVLTKGIAGIGKTFSVNKFILDWAEGRANLD-VDCMFLLPFREINLMIKDGDVSLHKFLLKLFPDITGVETTPFYEKCKLLFIFDGLDESRLDLNFN-LSSVDDVHSCASIDGLFTSLIKGRLLRSSLIWVTSRPAAANRIPSYHVG-LFTEVRGFTDKQKEEYFRKKVPDEDQASRIISHIRTSRSLYIMCHIPVFCWIIATVLQDILQ----------------KNKGED----IPSTLTEMYIHFLLIQMNIKNQKYDEKLIRDRTELLGSNRDMISKLAKLAFEQLKKENVMFYREDLAACGINAD--EEFTGLCTEIFKKDSVLHELKVYYFIHLSVQEFLAALHVFLCYLELEK--------DMNLTDS----------------------DLMFFLEDSRPKQKELLHVLLRKAIDKAEKSDRGHFDLFLRFLLGISLESNQKLLIGILNETKNSKQSISKTVQYLKQLQ--NNDKCPDKSINHFFCILELQDRTLYQ-------QIMKYLRSK---TNRPKVMSRSNCSALVYVLLMSQEVLDKFNPKLFNKT-------------YAGCRILVPAVRCSRKALFSDCGLTETCFETVALALQLENCPLVELDLSYNYSLEAAVNVMCAGLKSPHCHLESLRLAGCHLGQDSCMQVVSALQSISHRLKELDLSGNDLQDSGLQKLLQGMENTEKRLQVLRLSWCN----------------------------------------------------------LTEMSCQQLSTILS-SNSVFRELDLSNNDLQDSGVKLLSDGLKSPNCKLKILR-------------------------------------------------------------------LSGCMVTEEGCGFLSSALSSNPSHLRELDLSYNHPGQSGVQLLQHTLEDPHCKLKTLKTDPMGD---------HLMKPGI-----------------VKYAFNLTLNPNTAHVHLLLSDGDRKVT-LKE-------KQPYPD------DPERFE------------------------------------------------------------------EHHQVLSRESLSGRCYWETEWTGQEG-----------------------------TVGVAYES----IPRKPDDLLYGRCMLGNNIISWKITCGSR----------------------------------------------THVSHAEE---DITVKSP-SSGSCKR-------------VGVYVDTTAGVLSFYHVFD--TLTHLYT------------------------------------------------------------------------------------------------------------------------FLMPFTQPLYA---AFR--------VD-GESVSICPIP---------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D4A523-1", "uniprot_id": "NLRP3_RAT", "id": "D4A523-1", "name": "NACHT, LRR and PYD domains-containing protein 3", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKMMSVRCKLAQYLEDLEDVDLKKFKMHLEDYPPEKGCVPIPRGQMEKADHLDLATLMIDFNGEEKAWGMAVWIFAAINRRDLWEKAKKDQPEWN--DACTSNLSMVCQEDSLEEEWIG---------------------------------------LLGYLSRISICKKKKDYCKIYRRHVRSRFYSIKDRNARLGESVDLNRRYTQLQLVKEHPSKQEREHELLTIGR-TKMWDRPMSSLKLELLFEPEDE---------HLEPVHTVVFQGAAGIGKTILARKIMLDWALGKLFKDKFDYLFFIHCREVSLRAP---KSLADLIISCWPDPNPPVCKILCKPSRILFLMDGFDELQGAFDEHIEEVCTDWQKAVRGDILLSSLIRKKLLPKASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSNELQAREAFRLIQENEILFTMCFIPLVCWIVCTGLKQQMETG--------------KSLAQT-----SKTTTAVYVFFLSSLLQSRGGIEEH-----------LFSAYLPGLCSLAADGIWNQKILFEECDLRKHGLQKTDVSAFLRMN--VFQKEVDCER--FYSFSHMTFQEFFAAMYYLLEEEEEGVTVR-----------------------------------------KGPEGCSDLLNRDVKVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLS-CKISQQVRLELLKWIEVKAKAKKLQRQPSQLELFYCLYEMQEEDFVQSAMGHFPKIEINLSTRMDHVVSSFCIKNCHRVKTLSLGFLHNSPKEEEEEKRGSQP------------LDQVQCVFP-DPHVACSSRLVNCCLTSSFCRGLFSSLSTNQS-LTELDLSDNTLGDPGMRVLCEALQHPGCNIQRLWLGRCGLTHQCCFNISSVLSS---------------------------------------------------------------------------------------------------------------------SQKLVELDLSDNALGDFGVRLLCVGLKHLLCNLQKLWLVS-------------------------------------------------------------------CCLTSACCQDLALVLSSNHS-LTRLYIGENALGDSGVQVLCEKMKDPQCNLQKLGLVNSGLTSLCCSALTSVLKTNQN-----------------LTHLYLRSNALGDMGLKLLCEGLLHPDCKLQ--------------------------------------------------------------------------------------------------MLELDNCSLTSHSCWD---------------------------------LSTILTHN--------------QSLRKLNLSNNDLGDLC----------------------------------------------VVTLCEVLK---QQGCLLQSLQLGEMY-------------LNCETKRTLEALQEEKPELTVVFEISW------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R4B8-1", "uniprot_id": "NLRP3_MOUSE", "id": "Q8R4B8-1", "name": "NACHT, LRR and PYD domains-containing protein 3", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTSVRCKLAQYLEDLEDVDLKKFKMHLEDYPPEKGCIPVPRGQMEKADHLDLATLMIDFNGEEKAWAMAVWIFAAINRRDLWEKAKKDQPEWN--DTCTSHSSMVCQEDSLEEEWMG---------------------------------------LLGYLSRISICKKKKDYCKMYRRHVRSRFYSIKDRNARLGESVDLNSRYTQLQLVKEHPSKQEREHELLTIGR-TKMRDSPMSSLKLELLFEPEDG---------HSEPVHTVVFQGAAGIGKTILARKIMLDWALGKLFKDKFDYLFFIHCREVSLRTP---RSLADLIVSCWPDPNPPVCKILRKPSRILFLMDGFDELQGAFDEHIGEVCTDWQKAVRGDILLSSLIRKKLLPKASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSNELQAREAFRLIQENEVLFTMCFIPLVCWIVCTGLKQQMETG--------------KSLAQT-----SKTTTAVYVFFLSSLLQSRGGIEEH-----------LFSDYLQGLCSLAADGIWNQKILFEECDLRKHGLQKTDVSAFLRMN--VFQKEVDCER--FYSFSHMTFQEFFAAMYYLLEEEAEGETVR-----------------------------------------KGPGGCSDLLNRDVKVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLS-CKISQQVRLELLKWIEVKAKAKKLQWQPSQLELFYCLYEMQEEDFVQSAMDHFPKIEINLSTRMDHVVSSFCIKNCHRVKTLSLGFFHNSPKEEEEERRGGRP------------LDQVQCVFP-DTHVACSSRLVNCCLTSSFCRGLFSSLSTNRS-LTELDLSDNTLGDPGMRVLCEALQHPGCNIQRLWLGRCGLSHQCCFDISSVLSS---------------------------------------------------------------------------------------------------------------------SQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLQKLWLVS-------------------------------------------------------------------CCLTSACCQDLALVLSSNHS-LTRLYIGENALGDSGVQVLCEKMKDPQCNLQKLGLVNSGLTSICCSALTSVLKTNQN-----------------FTHLYLRSNALGDTGLRLLCEGLLHPDCKLQ--------------------------------------------------------------------------------------------------MLELDNCSLTSHSCWN---------------------------------LSTILTHN--------------HSLRKLNLGNNDLGDLC----------------------------------------------VVTLCEVLK---QQGCLLQSLQLGEMY-------------LNRETKRALEALQEEKPELTIVFEISW------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96P20-1", "uniprot_id": "NLRP3_HUMAN", "id": "Q96P20-1", "name": "NACHT, LRR and PYD domains-containing protein 3", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKMASTRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMIDFNGEEKAWAMAVWIFAAINRRDLYEKAKRDEPKWGSDNARVSNPTVICQEDSIEEEWMG---------------------------------------LLEYLSRISICKMKKDYRKKYRKYVRSRFQCIEDRNARLGESVSLNKRYTRLRLIKEHRSQQEREQELLAIGK-TKTCESPVSPIKMELLFDPDDE---------HSEPVHTVVFQGAAGIGKTILARKMMLDWASGTLYQDRFDYLFYIHCREVSLVTQ---RSLGDLIMSCCPDPNPPIHKIVRKPSRILFLMDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCTGLKQQMESG--------------KSLAQT-----SKTTTAVYVFFLSSLLQPRGGSQEH-----------GLCAHLWGLCSLAADGIWNQKILFEESDLRNHGLQKADVSAFLRMN--LFQKEVDCEK--FYSFIHMTFQEFFAAMYYLLEEEKEGRTN-------------------------------------------VPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLS-CKISQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTRMDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRH------------LDMVQCVLPSSSHAACSHGLVNSHLTSSFCRGLFSVLSTSQS-LTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRCGLSHECCFDISLVLSS---------------------------------------------------------------------------------------------------------------------NQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLVS-------------------------------------------------------------------CCLTSACCQDLASVLSTSHS-LTRLYVGENALGDSGVAILCEKAKNPQCNLQKLGLVNSGLTSVCCSALSSVLSTNQN-----------------LTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQ--------------------------------------------------------------------------------------------------VLELDNCNLTSHCCWD---------------------------------LSTLLTSS--------------QSLRKLSLGNNDLGDLG----------------------------------------------VMMFCEVLK---QQSCLLQNLGLSEMY-------------FNYETKSALETLQEEKPELTVVFEPSW------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . : :: ** : : : .::: : : :* ..*: * *****: ..*:::*** . :: : *::.* .* :: *: **:** : *: .:: ** : :*:**.* : .*: **.: :: :*: : . :: : : :: . * ** **:.*** .. * . : . * * :: :* : .:* : . :::* ** *: :: : .: * *::.**.:**.. * : : : **:.. . : :: :. : *: *: : : . :: : : : : : . : : . ", "identical_positions": 61, "similar_positions": 124, "identity": "2.81%" }, { "cls_id": "homologset.agr.RGD:1308315", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "O76041-1", "uniprot_id": "NEBL_HUMAN", "id": "O76041-1", "name": "Nebulette", "aln": "MRVPVFEDIKDETEEEKIGEEENEEDQVFYKPVIEDLSMELARKCTELISDIRYKEEFKKSKDKCTFVTDSPMLNHVKNIGAFISEAKYKGTIKADLSNSLYKRMPATIDSVFAGEVTQLQSEVAYKQKHDAAKGFSDYAHMKEPPEVKHAMEVNKHQSNISYRKDVQDTHTYSAELDRPDIKMATQISKIISNAEYKKGQGIMNKEPAVIGRPDFEHAVEASKLSS---------------QIKYKEKFDNEMKDKKHHYNPLESASFRQNQLAATLASNVKYKKDIQNMHDPVSDLPNLLFLDHVLKASKMLSGREYKKLFEENKGMYHFDADAVEHLHHKGNAVLQSQVKYKEEYEKNKGKPMLEFVETPSYQASKEAQKMQSEKVYKEDFEKEIKGRSSLDLDKTPEFLHVKYITNLLREKEYKKDLENEIKGKGMELNSEVLDIQRAKRASEMASEKEYKKDLESIIKGKGMQAGTDTLEMQHAKKAAEIASEKDYKRDLETEIKGKGMQVSTDTLDVQRAKKASEMASQKQYKKDLENEIKGKGMQVSMDIPDILRAKRTSEIYSQRKYKDEAEKMLSNYSTIADTPEIQRIKTTQQNISAVFYKKEVGAGTAVKDSPEIERVKKNQQNISSVKYKEEIKHATAISDPPELKRVKENQKNISNLQYKEQNYKATPVSMTPEIERVRRNQEQLSAVKYKGELQRGTAISDPPELKRAKENQKNISNVYYRGQLGRATTLSVTPEMERVKKNQENISSVKYTQDHKQMKGRPSLILDTPAMRHVKEAQNHISMVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVHPHIVEMDRRPGIIVDLKVWRTDPGSIFDLDPLEDNIQSRSLHMLSEKASHYRRHWSRSHSSSTFGTGLGDDRSEISEIYPSFSCCSEVTRPSDEGAPVLPGAYQQSHSQGYGYMHQTSVSSMRSMQHSPNLRTYRAMYDYSAQDEDEVSFRDGDYIVNVQPIDDGWMYGTVQRTGRTGMLPANYIEFVN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q0II04-1", "uniprot_id": "NEBL_MOUSE", "id": "Q0II04-1", "name": "Nebulette", "aln": "MKVPVSGDVKEETEEENVEQEENQEAKVSLKPVIEDLSMELARKCTELISDIHYKEEYKKSKDKCTFVTDTPMLNHVKNIGAFISEAKYKGTIKADLSNCLYKDMPATIDSVFAREVSQLQSEVAYKQKHEAEKGFSDYTHMKEPPEVRRAMEVNRHQSNISYRKDMQGTHTYTAELDRPDIKKATQISKIISDAEYKKGQGIVNKEPSVIGRPDFEHAVGASKLSS---------------QVKYKEKFDNEMKEKSHHYNPLGSAFFRQHQFAAVLAS-----------------------------------DWEYKRDFEENKGLYHFDAEAPEHLHHKGNATLQSQVKYREEYEKNKGKSMLEFVETPSYQSSKEAQKMQSEKVYKEDFEKEIKGRSSLDLDKTPAFLHVKHITNLMREKEYKKDLENEIKGKGMELSSEVLDIQRAKRASEMASEK-------------------------------------DYKRDLETEIKGKGMQVSTDTLDVQRAKRASEMASQVRMV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A164-1", "uniprot_id": "D4A164_RAT", "id": "D4A164-1", "name": "", "aln": "MKVPVSGDVKEETEEENVEEEEKPEDEVFLKPVVEDLSMELARKCTELISDIHYKEDYRKSKDKCTSVTDTPTLNHVKNISAFISETKYKGTIKADLSNCLYKDMPATIDSVFAREVSQLQSEVAYKQKHEAEKGLSDYAHMKEPPEVRHAMEVNRHQSNISYRKDVQGTHTYTAEMDRPDIKKATQISKIISNVIS---LSILCNSDFSLFWGEMEHSVDSWKLMTSQLCPELHLDMQIIGEVKYKEKFDNEMKGKGHHYNPLGSASFRQHQLATVLASDVKYKKDVQTMHEPVSDLPNLLFLDHALKASRMLSGWEYKKNFEENKGSYHFDAEAPEHLHHRGNATLQSQVKYREEYEKNKGKTMLDFVETPSYQSSKEAQKMQSEKVYKEDFEKEIKGRSSLDLDKTPAFLHVKHISNLMREKEYKKDLENEIKGKGMELSSEVLDIQRAKRASEMASEKEYKKDLELEIKGKGMQIDADTLEIQRVKRAAKIASEKDYKRDLETEIKGKGMQVSTDTLDVQRAKRASEMASQKQYRKDLENEIKGKGMQVNVDIPDMLRAKRASEIYSQKKYKDEAEKMLSNYSTVAVTPEIQRIKTTQQNISNVSYKEEVRAGTAVRNTPEIERVKKNQHNISSVKG---IKHATAISDPLELKR----------FQYKEPTYKATPVTMTPEIERVRRNQEQLSAVKHKGELKQATSILDLPGLKRVRENQKTISNVYYKGQLGRATALSVTPEMERVKKNQENISSVKYTQDHKQMKGRPCVILDTPALRHVKEAQNHVSMVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVQPHVVEMDRRPGIIVDLKVWRTDPGSIFDIDPLEDNIQSRSLHMLSEKASQYQSRLSRSHSGSTFGTGLGDDKSEISELYPSFSCCSEVTRPSDEGAPVLPGAYQQSHSQGYGYMHQTSVSSVRSMQHSANLRTYRAMYDYSAQDEDEVSFRDGDYIVNVQPIDDGWMYGTVQRTGRTGMLPANYIEFVN", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:*** *:*:*****:: :**: * :* ***:******************:***:::******* ***:* *******.*****:************.*** ********** **:************:* **:***:********::*****:**********:*.****:**:****** *********:. .*: :. : ::**:* : ** : ::*********** * ****** ** ***:*:*:.*** . ***: ****** *****:* *****:***.*******:*********.**:********:********************************* *****:*:**:********************.******************* ****************************:******* : ", "identical_positions": 350, "similar_positions": 61, "identity": "34.01%" }, { "cls_id": "homologset.agr.RGD:1308316", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R4V1-1", "uniprot_id": "NFAM1_MOUSE", "id": "Q8R4V1-1", "name": "NFAT activation molecule 1", "aln": "MESWLLRRGARVRCLHPPSWLPA-WCFLCLLPVPQTLQLTGLVSLTHTSLPIMVSLANTDVFFSCRIEDFTRLQR-DLPVKLFHTDIHGRRRWEKQINCQHRPGMEN--HTRDCMVKLSQANTSATGIYYFIVEG-EETYQSDGVVILVRDTVYQPPAFKVQEALMLGFTSLMSVLGVLGTALLLWKKKQISVLGKHTAKTCSGLKSTVGTTKPPAESVYTSLQRRETEVYACMKEETG-SPVFSQSPATKEKLNRFEDDNEFNLVYENL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1M0C3-1", "uniprot_id": "F1M0C3_RAT", "id": "F1M0C3-1", "name": "", "aln": "MASAVWGPGGISAPLQPAPSRVL-PPFLRLLLVPWTLQLAGGITVTHTGLPIRVLLANTDMSFSCKIHNFLGTEIFMFTVSFFYMDIHGEKSSEKPIACQPRPGMEN--QTMDCMVQLSLPNASATGTYYCRVKG-HVTSQSDGIFILVRDTGYQPPSFKVQEALLLSFTGLLSVLGVLGTALLFWKKKQIAVLGKHTAKTCPSPKPTIGTTKPPAESIYTSLQRRETEVYACIEGETG-SPVSSQSPDTKEKMNRVEDDREFNLVYENL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NET5-1", "uniprot_id": "NFAM1_HUMAN", "id": "Q8NET5-1", "name": "NFAT activation molecule 1", "aln": "MENQPVRWRALPGLPRPPGLPAAPWLLLGVLLLPGTLRLAGGQSVTHTGLPIMASLANTAISFSCRITYPYTPQFKVFTVSYFHEDLQGQRSPKKPTNCHPGLGTENQSHTLDCQVTLVLPGASATGTYYCSVHWPHSTVRGSGTFILVRDAGYREPPQSPQKLLLFGFTGLLSVLSVVGTALLLWNKKRMRGPGKDPTRKCPDPRSASSPKQHPSESVYTALQRRETEVYACIENEDGSSPTAKQSPLSQERPHRFEDDGELNLVYENL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . . :*. :* :* :* **:*:* ::***.*** . **** : ***:* : :.*. *: *::*.: :* *: * ** :* ** * * ..:**** ** *. . * :..* .*****: *: *. . *: *::.**.*:***.*:*****:*:**:: **..::.*.. :.: ...: *:**:**:***********:: * * **. .*** ::*: :*.*** *:*******", "identical_positions": 109, "similar_positions": 79, "identity": "40.37%" }, { "cls_id": "homologset.agr.RGD:1308317", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q80UX8-1", "uniprot_id": "ABHDD_MOUSE", "id": "Q80UX8-1", "name": "Protein ABHD13", "aln": "MEKSWMLWSFIERWLLALASWSWALCRISLLPLIVTFHLYGGIVLLLLIFVSIAGILYKFQDVLLYFPEQPSSSRLYVPMPTG--IPHENIFIRTKDGVRLNLILVRYTGDNSPYCPTIIYFHGNAGNIGHRLPNALLMLVNLRVNLVLVDYRGYGKSEGEASEEGLYLDSEAVLDYVMTRPDLDKTKVFLFGRSLGGAVAIHLASENSH--RISAIMVENTFLSIPHMASTLFSFFPMRYLPLWCYKNKFLSYRKISQCR--MPSLFISGLSDQLIPPVMMKQLYELSPSRTKRLAIFPDGTHNDTWQCQGYFTALEQFIKEVIKSHSPEDMTKTSSNVTII------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A1B6-1", "uniprot_id": "D4A1B6_RAT", "id": "D4A1B6-1", "name": "Protein ABHD13", "aln": "MEKPWMLWSFIERWLLALVSWSWALCRISLLPLIVTFHLYGGIVLLLLIFVSIAGILYKFQDVLLYFPEQPSSSRLYVPMPTG--IPHENIFIRTKDGVRLNLILVRYTGDNSPYCPTIIYFHGNAGNIGHRLPNALLMLVNLKVNLVLVDYRGYGKSEGEASEEGLYLDSEAVLDYVMTRPDLDKTKVFLFGRSLGGAVAIHLASENSH--RISAIMVENTFLSIPHMASTLFSFFPMRYLPLWCYKNKFLSYRKISQCR--MPSLFISGLSDQLIPPVMMKQLYELSPSRTKRLAIFPDGTHNDTWQCQGYFTALEQFIKEVIKSHSPEDMTKTSSNVTII------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7L211-1", "uniprot_id": "ABHDD_HUMAN", "id": "Q7L211-1", "name": "Protein ABHD13", "aln": "MEKSWMLWNFVERWLIALASWSWALCRISLLPLIVTFHLYGGIILLLLIFISIAGILYKFQDVLLYFPEQPSSSRLYVPMPTG--IPHENIFIRTKDGIRLNLILIRYTGDNSPYSPTIIYFHGNAGNIGHRLPNALLMLVNLKVNLLLVDYRGYGKSEGEASEEGLYLDSEAVLDYVMTRPDLDKTKIFLFGRSLGGAVAIHLASENSH--RISAIMVENTFLSIPHMASTLFSFFPMRYLPLWCYKNKFLSYRKISQCR--MPSLFISGLSDQLIPPVMMKQLYELSPSRTKRLAIFPDGTHNDTWQCQGYFTALEQFIKEVVKSHSPEEMAKTSSNVTII------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q32LS6-1", "uniprot_id": "ABHDD_DANRE", "id": "Q32LS6-1", "name": "Protein ABHD13", "aln": "MEKPWRLWGPLEACLLSVCAWSWGFCRVSLLALILTFHLYGGFVLLGLILASLAGILYKFQDVLLYFPDQPSSSRLYVPMPTG--IPHENVYIRTKDGIRLNLILLRYTGENPAGAPTILYFHGNAGNIGHRVPNALLMLVNLKANVVLVDYRGYGKSEGDPSEDGLYQDAEATLDYVMTRPDIDKTKVVLFGRSLGGAVAIRLASCNPH--RVAAIMVENTFLSIPHMAATLFSFFPMRYLPLWCYKNKFLSYRHVVPCR--MPSLFISGLSDQLIPPVMMKQLYELSPSRTKRLAIFPEGTHNDTWQCQGYFSALEQFMKELLKSHAREETTQGTASVTII------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O76462-1", "uniprot_id": "O76462_DROME", "id": "O76462-1", "name": "", "aln": "MKEVGIALPKSRGVGVGVLA--------AFLLCFIFYYFYGGYMTLALFAGIILLIFYYAQDLLLYHPDLPANSRIYIPIPTMHNLPHITVSIKTPDDVTLHAFWVTQPEERSKSSPTLLYFHGNAGNMGHRMQNVWGIYHHLHCNVLMVEYRGYGLSTGVPTERGLVTDARAAIDYLHTRHDLDHSQLILFGRSLGGAVVVDVAADTVYGQKLMCAIVENTFSSIPEMAVELVHP-AVKYIPNLLFKNKYHSMSKIGKCS--VPFLFISGLADNLVPPRMMRALYTKCGSEIKRLLEFPGGSHNDTWIVDGYYQAIGGFLAELQQQPLLKAPEKSNVWVELEHKIIDV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P42840-1", "uniprot_id": "YN60_YEAST", "id": "P42840-1", "name": "Uncharacterized membrane protein YNL320W", "aln": "------------------------------MLWKVSKMFLGGLVALTTIS---VATLYHYQNRLVY-PSWAQGARNHVDTPDSRGIPYEKLTLITQDHIKLEAWDIK----NENSTSTVLILCPNAGNIGYFILIIDIFYRQFGMSVFIYSYRGYGNSEGSPSEKGLKLDADCVISHLSTDSFHSKRKLVLYGRSLGGANALYIASKFRD--LCDGVILENTFLSIRKVIP---YIFPLLKRFTLLCHEIWNSEGLMGSCSSETPFLFLSGLKDEIVPPFHMRKLYETCPSSNKKIFEFPLGSHNDTIIQDGYWDIIRDFLIEKGFI----------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : ** : * : :* *: *:* *. . .:* :: * :*: .: : * * : *. : . .*:: : ****:*: : : :: .:.: .***** * * .:* ** *: ..:.:: * .: ::.*:******* .: :*: ::**** ** .: .: :: : * : * * **:*** *:::** *: ** . * *:: ** *:**** :**: : *: * ", "identical_positions": 74, "similar_positions": 80, "identity": "21.2%" }, { "cls_id": "homologset.agr.RGD:1308318", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZYT2-1", "uniprot_id": "D3ZYT2_RAT", "id": "D3ZYT2-1", "name": "Small ribosomal subunit protein uS5m", "aln": "MAAAVRAAGCLPALCSAPAGHFLSRQLSLNTFPVAATSFLAAKTAFSHGSLSPRETRHNHCLTSLSHALQTQCCISSPSNWTGQQYRPYSFFTKLTAEELWKGALAETGAGARKGRGKRTKKKKKKDLNKGQIIGEGRSGFLWPGLNVPLIKSGVVQNIGQRSKEEQQKVEADMAEQREEWDRKRKIKVKRERGWSGNTWGGVSIGPPDPGPNGETYEDFDTRILEVRNVFNMTAKEGRKKSVRVLVAVGNGNGAAGFAVGKAADRA-DAFRKAKNRAIHYLHYIERYEGHTIFHDISLRFKRTHIRMKKQPRGYGLRCHRAIITICRLIGIKDMYAKVNGSVNMLNLTRGLFHGLAR-QETHQHLADKKGLHVVEFREECGPLPIVVASPHGALSKEPEPEPEVPDTKLDWQDVKAMQGMKRSVWFNLKRSAT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99N87-1", "uniprot_id": "RT05_MOUSE", "id": "Q99N87-1", "name": "Small ribosomal subunit protein uS5m", "aln": "MAAAVRAAGCLPALCSLQAGHFLSRQLSLNAFPVAATSFLAVKTALSHGSLSSRETRRNHCLTSLSHVLQTQCCVSSPGNWTGQQCRPYSFFTKLTAEELWKGALAETGAGARKGRGKRTKKKKRKDLNRGQIIGEGRSGFLWPGLNVPLIKSGVVQNIGQRSKEEQQKVEATMVEQREEWDRKRKIKVKRERGWSGNTWGGVSIGPPDPGPNGETYEDFDTRILEVRNVFNMTAKEGRKKSVRVLVAVGNGNGAAGFAIGKAADRG-DAFRKAKNRAIHYLHYIERYEGHTIFHDISLRFKRTQIRMKKQPRGYGLRCHRAIITICRLIGIKDMYARVTGSMNMLNLTRGLFHGLAR-QETHQHLADKKGLHVVEFREECGPLPIVVASPHGALSKEPEPEPEVPDTKLDWQDVKAMQGLKRSVWFNLKRPAT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P82675-1", "uniprot_id": "RT05_HUMAN", "id": "P82675-1", "name": "Small ribosomal subunit protein uS5m", "aln": "MATAVRAVGCLPVLCSGTAGHLLGRQCSLNTLP--AASILAWKSVLGNGHLSSLGTRDTHPYASLSRALQTQCCISSPSHLMSQQYRPYSFFTKLTADELWKGALAETGAGAKKGRGKRTKKKKRKDLNRGQIIGEGRYGFLWPGLNVPLMKNGAVQTIAQRSKEEQEKVEADMIQQREEWDRKKKMKVKRERGWSGNSWGGISLGPPDPGPCGETYEDFDTRILEVRNVFTMTAKEGRKKSIRVLVAVGNGKGAAGFSIGKATDRM-DAFRKAKNRAVHHLHYIERYEDHTIFHDISLRFKRTHIKMKKQPKGYGLRCHRAIITICRLIGIKDMYAKVSGSINMLSLTQGLFRGLSR-QETHQQLADKKGLHVVEIREECGPLPIVVASPRGPLRKDPEPEDEVPDVKLDWEDVKTAQGMKRSVWSNLKRAAT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P33759-1", "uniprot_id": "RT05_YEAST", "id": "P33759-1", "name": "Small ribosomal subunit protein uS5m", "aln": "---------------------MFKRQLST------SVRYLQHYDESLLSRYYPESLLKSIKLAQQTIPEDTKFRVSR-----NVEFAPPYLDDFTKIHPFWDYKPGMPHLHAQEENNNFS--IFRWDQVQQPLPGEG--NILPPGVSLPNDGG---------RKSKSADVAAGLHKQTG----------------------------VDP---DYITRKLTMKPLVMKRVSNQTGK-GKIASFYALVVVGDKNGMVGLGEGKSREEMSKAIFKAHWDAVRNLKEIPRYENRTIYGDIDFRYHGVKLHLRSAKPGFGLRVNHVIFEICECAGIKDLSGKVYKSRNDMNIAKGTIEAFTKAQKTLDEVALGRGKKLVDVRKVYYSS--------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: ** * :. * . . . :. : :*: :* . : * : . . :*. . . *:: ..: : : * : : *** .:* **:.:* . *.:. .* * : :* ** . ..: : * ::.* . *.* *: *. .**.**: :* .*:. **: :. .*: **: *:: *: * ***.:**: **.:*:: .:::::. *:*** ::.*: **. ****: .:* * * :.:::* :..::: *:* :.:* :* ::*:.*: . ", "identical_positions": 72, "similar_positions": 116, "identity": "16.59%" }, { "cls_id": "homologset.agr.RGD:1308319", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AVZ7-1", "uniprot_id": "A0A8I6AVZ7_RAT", "id": "A0A8I6AVZ7-1", "name": "", "aln": "METLNGPAGGGAPDPKPQPAGQHHRHHHLHPLAERRRLHRAPSPARPFLKDLHTRPAT---ATPSAGRAPTPAAPRSPSLTGKAPPSPGSPAAPGRLSRRSGVVPGAKDKPPPGAGARSAGGAKAAPGTRRATRAGPAEPLSRVGRPAGAEPPPALSKGRKAKRGPGTPPARAVVPPAPAARVPAVTLSVTSVAG-----TRISHTDSSSDLSDCASEPLSDEQRLLPAASSDAESGTGSSDREPLRGAPTPSSGSRGPPPGSPEPPTLLAAPPVAGACLGGRSSPGGTPSGSPGPGSQEDVGGRAPPERTILGTPKEPSLG-EQPRLLVVAEEEELLREMEELRSENDYLKDELDELRAEMEEMRDSYLEEDGYQLQELRRELDRANKN-CRILQYRLRKAEQKSLKVAETGQVDGELIRSLEQDLKVAKDVSVRLHHELETVEEKRAKAEDDNETLRQHMIEVEISRQALQNELERLRESSLKRRGSREIYKEKKLVNQDDSADLKCQLQFAKEEASLMRKKMAKLGREKDELEQELQKYKSLYGDVDSPLPTGEAGGPPSTREAELKLRLKLVEEEASILG-RKIVELEVENRGLKAEMEDIRVQHEREGTSRDHVPGIPTSPFGDSMESSTELRRHLQFVEEEAELLRRSISEIEDHNRQLTHELSKFKFEPHQESGWLGDGVSKGPGASAPLQEELKSARLQIDELSGKVLKLQCENRLLLSNAQRCDLAAHLGLRAPSPRDSDAESDAGKKESDGEEGRLPQPKREGPVGGESDSEDMFEKTSGFGSGKPSEASEPCPTELLRVREDTECLVTMKLEAQRLERTVERLISDTDGFIRDSGLRGNG-SASPGVQGEG-EG--SLNEPHLLETINGRMKAFRKELQAFLEQMSRIVDGLSPLSHLTESSSFLSTVTSVSRDSPIGTLGKELGPDLQSKLREQLEWQLGQDRGDEREGLRLRATRELHRHADGDSGS-HGLGGQSCFNLELRGSPVLPEQSVSVEELQGQLQQAARLHQEETETYTNKIRKMEEDHLYALRWKELEMHSLALQNTLHKRTWSDEKNMLQQELRSLKQNIFLFYVKLRWLLKHWRQGKQMEEGGEDFAESEHPENVPGLAELGVQGGHRTDGTDQEGTDRGCGLPMGEPAPHSPVQMSEHGSRLPTADGGPLSKQVVENQQLFRALKALLEDFRSELREDEHARLRLQQQYASDKAAWDVEWAVLKCRLEQLEEKTEKSLGELDSSAEGKGALKKEREVHQKLLADSHGLVMDLRWQIHHREKNWNREKVELLERLDNERQEWGRQKEELLWRVEQLQKEKSPRRSGSFLCSPREDDNRPYPHQGSLHPSRPVSMWPCEDTDSIPFEDRPLSKLKESDRCSASENLYLDALSLDDDSEDPPP------LRNCLAEEEESRKGNLQRAVSVSCMSEFQRLMDVSPFLP--EKGLPSASSREDVTPPLSPDDLKYIEEFNSKDWDYTS----PRAGADRPPDLWADRTEVGRVGHEATAEPCPDSSWYLTTSVTMTTDTMTSPEHCQKQPLRTHVLTEQSGVHVLHSPPAIRRVDSIASGGEGRSRVDPEGPFPMSRARGNLADAKGGHPEPVLN-RWPCTPPRHPRDCVEGSLRPLDRPLCPSLGFASPLNSLDMSRN-MSDDMKEVAFSVRNAMCSGPAEPQVRDMACQTNGSRTAGTQTIQTISVGLQTEALRASGVTS--SPHKCLTPKAGGGTTPVSSPSRSLRSRQVAPAIEKVQAKFERTCCSPKYGSPKLQRKPPSKADQPNSRTSPGMPQKGFSESAWARSTTTRESPVHTTINDGLSSLFNIIDHSPV-------GVRAGSRSRSAEPRQELGPGQETGTSSRGRSPSPLGVG---SEMYREDGGESTPVRQDLSAPPGYTLTENVARILNKKLLEHALKEERKQATHGSSGLTSDSHPGEAVPAEPGSMEELPCSALAPSLEPCFSRPERPANRRLPSRWAPPSPTASQSQSPGDPVSLEERGEEDPPEEKPHP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UHU5-1", "uniprot_id": "MTCL1_MOUSE", "id": "Q3UHU5-1", "name": "Microtubule cross-linking factor 1", "aln": "METLNGPAGGGAPDTKPQPAGQHHRHHHLHPLAERRRLHRAPSPARPFLKDLHTRPAT---ATPSAGRAPTPAAPRSPSLAGKAPPSPGPPAAPGRLSRRSGVVPGAKDKPPPGAGARSAGGAKAVPGTRRAARAGPAEPLSRVGRPTGAEPPPAVAKGRKTKRGPGTPPARAVVPPARASRVPAVTLSVTSVAG-----CRINHTDSSSDLSDCASEPLSDEQRLLPAASSDAESGTGSSDREPIRGAPTPSSGSRGPPPGSPEPPILLAAPPVASACLGGRSSPGGASTGSPGPGSQEDVGGRAPPERTILGTSKEPSLG-EQPRLLVVAEEEELLREMEELRSENDYLKDELDELRAEMEEMRDSYLEEDGYQLQELRRELDRANKN-CRILQYRLRKAEQKSLKVAETGQVDGELIRSLEQDLKVAKDVSVRLHHELETVEEKRAKAEDDNETLRQQMIEVEVSRQALQNEVERLRESSLKRRGSREMYKEKKLVNQDDSADLKCQLQFVKEEASLMRKKMAKLGREKDELEQELQKYKSLYGDVDSPLPTGEAGGPPSTREAELKLRLKLVEEEASILG-RKIVELEVENRGLKAEMEDIRVQHEREGTGRDHVPSTPTSPFGDSMESSTELRRHLQFVEEEAELLRRSISEIEDHNRQLTHELSKFKFEPHQESGWLGDGVSKGPAASVPLQEELKSARLQIDELSGKVLKLQCENRLLLSNAQRGDLAAHLGLRAPSPRDSDAESDAGKKESDGEEGRLPQPKREGPVGGESDSEDMFEKTSGFGSGKPSEASEPCPAELLRVREDTECLVTIKLEAQRLERTVERLISDTDGFIHDSGLRGNG-LASPGVQGGGGEGN-SPSEPHLLETINVRMKAFRKELQAFLEQMSRIVDGLSPLSHLTESSSFLSTVTSVSRDSPIGTLGKELGPDLQSKLREQLEWQLNQDRGDEREGLRLRATRELHRRADGDSGSHHGLGGQSCFNLEM-----------------------------------------EEDHLYALRWKELEMHSLALQNTLHKRTWSDEKNLLQQELRSLKQNIFLFYVKLRWLLKHWRQGKQMEEGGEDLEESEHPENVPGLAELGVQGVHQTDGIDQEDADQGCSLPMGEHAPHSLVQISEHGSRLQSSDGGPLNKQVVENQQLFRALKALLEDFRSELREDEHARLRLQQQYASDKAAWDVEWAVLKCRLEQLEEKTEKSLGELDSSAEGKGALKKEREVHQKLLADSHSLVMDLRWQIHHREKNWNREKVELLERLDSERQEWGRQKEELLWRVEQLQKEKSPRRSGSFLCSRREDDTRPYPHQGSLHSSRPVSMWPCEDADSIPFEDRPLSKLKESDRCSASENLYLDALSLDDDPGDPPP------LRNCLAEEEESRKGNLQRAVSVSCMSEFQRLMDVSPFLP--EKGLPSAGSKEDVTPPLSPDDLKYIEEFHSNDWDYAS----PRAEADRPPDPWADRTEMGRVGHEATTEPCPDPSWYLTTSVTMTTDTMTSPEHCQKQPLRTHVLTEQSGVHVLHSPPAIRRVDSIASGGEGRSRADPEGPFPMSRARGNLADAKGGHPEPVLN-RWPCTPPRHPRDCVEGSLRPLDRPICPSLGFASPLNSLDMSKN-MSDDMKEVAFSVRNAICAGPAEPHVRDMACQTNGSRTAGTQTIQTISVGLQTEALRASGVTS--SPHKCLTPKAGGGTTPVSSPSRSLRSRQVAPAIEKVQAKFERTCCSPKYGSPKLQRKPLSKADQPNSRTSPGIPQKGFSESAWARSTTTRESPVHTTINDGLSSLFNIIDHSPI-------GVRAGSRSRSAEPRQELGPGQETGTSSRGRSPSPLGVG---SETFREEGGESTPVRQDLSAPPGYTLTENVARILNKKLLEHALKEERKQASHGSSGLTSDSHTGEPVPAEPGSMEELPCSALAPSLEPCFSRPERPANRRLPSRWAPPSPTASQSQSPGHPMSMEEHGEEDPPEEKPHL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y4B5-1", "uniprot_id": "MTCL1_HUMAN", "id": "Q9Y4B5-1", "name": "Microtubule cross-linking factor 1", "aln": "METLNGPAGGGAPDAKLQPPGQHHRHHHLHPVAERRRLHRAPSPARPFLKDLHARPAAPGPAVPSSGRAPAPAAPRSPNLAGKAPPSPGSLAAPGRLSRRSGGVPGAKDKPPPGAGARAAGGAKAALGSRRAARVAPAEPLSRAGKPPGAEPPSAAAKGRKAKRGSRAPPARTVGPPTPAARIPAVTLAVTSVAGSPARCSRISHTDSSSDLSDCPSEPLSDEQRLLPAASSDAESGTGSSDREPPRGAPTPSPAARGAPPGSPEPPALLAAPLAAGACPGGRSIPSGVSGGFAGPGVAEDVRGRSPPERPVPGTPKEPSLG-EQSRLVPAAEEEELLREMEELRSENDYLKDELDELRAEMEEMRDSYLEEDVYQLQELRRELDRANKN-CRILQYRLRKAEQKSLKVAETGQVDGELIRSLEQDLKVAKDVSVRLHHELKTVEEKRAKAEDENETLRQQMIEVEISKQALQNELERLKESSLKRRSTREMYKEKKTFNQDDSADLRCQLQFAKEEAFLMRKKMAKLGREKDELEQELQKYKSLYGDVDSPLPTGEAGGPPSTREAELKLRLKLVEEEANILG-RKIVELEVENRGLKAEMEDMRGQQEREGPGRDHAPSIPTSPFGDSLESSTELRRHLQFVEEEAELLRRSISEIEDHNRQLTHELSKFKFEPPREPGWLGEGASPGAGGGAPLQEELKSARLQISELSGKVLKLQHENHALLSNIQRCDLAAHLGLRAPSPRDSDAESDAGKKESDGEESRLPQPKREGPVGGESDSEEMFEKTSGFGSGKPSEASEPCPTELLKAREDSEYLVTLKHEAQRLERTVERLITDTDSFLHDAGLRGGAPLPGPGLQGEEEQGEGDQQEPQLLGTINAKMKAFKKELQAFLEQVNRIGDGLSPLPHLTESSSFLSTVTSVSRDSPIGNLGKELGPDLQSRLKEQLEWQLGPARGDERESLRLRAARELHRRADGDTGS-HGLGGQTCFSLEM-----------------------------------------EEEHLYALRWKELEMHSLALQNTLHERTWSDEKNLMQQELRSLKQNIFLFYVKLRWLLKHWRQGKQMEEEGEEFTEGEHPETLSRLGELGVQGGHQADGPDHD-SDRGCGFPVGEHSPHSRVQIGDHSLRLQTADRGQPHKQVVENQQLFSAFKALLEDFRAELREDERARLRLQQQYASDKAAWDVEWAVLKCRLEQLEEKTENKLGELGSSAESKGALKKEREVHQKLLADSHSLVMDLRWQIHHSEKNWNREKVELLDRLDRDRQEWERQKKEFLWRIEQLQKENSPRRGGSFLCDQKDGNVRPFPHQGSLRMPRPVAMWPCADADSIPFEDRPLSKLKESDRCSASENLYLDALSLDDEPEEPPAHRPEREFRNRLPEEEENHKGNLQRAVSVSSMSEFQRLMDISPFLP--EKGLPSTSSKEDVTPPLSPDDLKYIEEFN-KSWDYTP----NRGHNGGGPDLWADRTEVGRAGHEDSTEPFPDSSWYLTTSVTMTTDTMTSPEHCQKQPLRSHVLTEQSGLRVLHSPPAVRRVDSITAAGG-------EGPFPTSRARGSPGDTKGGPPEPMLS-RWPCTSPRHSRDYVEGARRPLDSPLCTSLGFASPLHSLEMSKN-LSDDMKEVAFSVRNAICSGPGELQVKDMACQTNGSRTMGTQTVQTISVGLQTEALRGSGVTS--SPHKCLTPKAGGGATPVSSPSRSLRSRQVAPAIEKVQAKFERTCCSPKYGSPKLQRKPLPKADQPNNRTSPGMAQKGYSESAWARSTTTRESPVHTTINDGLSSLFNIIDHSPVVQDPFQKGLRAGSRSRSAEPRPELGPGQETGTNSRGRSPSPIGVG---SEMCREEGGEGTPVKQDLSAPPGYTLTENVARILNKKLLEHALKEERRQAAHGPPGLHSDSHS-LGDTAEPGPMENQTVLLTAP--------------------WGL--------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M9PCE3-1", "uniprot_id": "M9PCE3_DROME", "id": "M9PCE3-1", "name": "", "aln": "MHHLYPSLKG----DQLCPLGFHPQTRYPTRCKRCFRDYKEHGARRAGEEVAASSPNLS---DAQSSRPSSRTWTSTQNLTSANATNGNDIVVHFNVELRKRPQSWAS-TPDIDEPDNVARRPPATASTSRAASSAEDQDVAVTVKLPVPPRRHTTALDIKEVEHAITPPTRVTSSPSKTSSIPDELVILSTDSLA----ERVRKMNLLKKQRSLNSRENSRE-RSVPRREEESESTATPTPVVPDRPERSKSGTSLNQLAQAEQKRAALPPKKVAVASTTTASSSNSSSTSLKTSNSTSASNEVKVVTSTSSSSTSSSSVRRKEADSVASKEIKRQTVPAASISHSNSTSSTASTASKSQDTNGMQEQMKALKLELETMKTRAEKAEREKSDILLRRLASMDTASNRTAASEALN---LQQKLNEMKEQLDRVTEDKRKLNLRMKELENKGSESELRRKLQAAEQICEELMEENQSAKKEILNLQAEMDEVQDTFRDDEVKAKTSLQKDLEKATKNCRILSFKLKKSDRKIETLEQERQ--SSFNAELSNKIKKLEEELRFSN---ELTRKLQAEAEELRNPGKKKAPMLGVLGKSTSADAKFTRESLTRGGSQED--PQHLQRELQDSIERETDLKDQLKFAEEELQRLR-----------DRERKRVRFSCGTQTEVPLEVVAFPRGTQTVATVQSDMSTSVENLVTSNVAVTQTDFEVPDRNVSIERETMSSPFAGLFPPSSSSRVGQSGSLLFPSAISHVLLSGAGRKLSPTPHPHRLAPEVHADRDEGISDEDDPAELRILLELNEQEASILRLKVEDLEKEN------AESKKYVRELQAKLRQDSSNGSKSSLLSLGTSSSAAEKKVKTLNEELVQLRRTLTEKEQTVDSLKNQLSKLDTLETENDKLAKENKR-------LLALRKASEKTGEVDQKMKESLAQAQ-RERDELTARLKRMQLEAEDKLPPR----TAKRVNDLTP--------------------------------------------KSHLKKWVEELEDEISEMRVMLSSSGTDQLKALQSAKGALEEDLRKCKQKLSLAEGDVQRLKLLN--GSSSKVSELEQKLKRGDEEAKKLNSKLKDLEDKVKKQEAQLKLGETSKSTWESQSKREKEKLSSLEKDMEKQAKEKEKLEAKISQLDAELLSAKKSAEKSKSSLEKEIKDLKTKASKSDSKQVQDLKKQVEEVQASLSAEQKRYEDLNNHWEKLSEETILMR----AQLTTEKQSLQAELNASKQKIAEMDTIRIERTDMARKLSEAQKRIADLQAKALKTVNG----NGAEYERTVLKNKLAEKEHEYERLRRENEMNIDLVFQLRKDNDDLNGKLSDYNRIEQAQSSLNGHGARREA------EIRELKEQLQSTELQMKSEVATVRLRYEQQVKNLSGELTSMQRQCERFKKDRDAFKQMLEVAQKKIGDLKANNTGRQSRGSMHSSDDDDKSKIAYLEQQIGHLEDQLVESRLESSKIKTELVSERSANEIKISEMQSKLNEFEEERVIGSGSTKLPGMKTKLELSWQKEREDQQRLLQETSTLARDLRQTLFEVERERDKERLESKRKLDQIKRATEEEMEEGRKKIAELQCDLLELRDVHAKLRTSNEKLRRERERYEKELIKRRMEADGGDRKVGALLQTVDELVKIAPDLKIVGSGGSARSSSSSGYDKNLRPEQPNVRRSRSPSPTLSSSQITSVLARLAEASEELR-KFQRVNEDEQERSRMRRSNLRRAASQENDPHGSTSSVASAAGSQRGGGRLSRNSSNNGSLIRKSLSLDHSIQRDQN-----IWRQDDGSVSSMQSIDSELG-GLVRDSSLDSRLDSRLSGGSTQSDIPRGPRKKKKGIMGKLRSLTKSSRNSESEISIQGSDSDISVASDMRSSKKDLRGRLSGMFKRSGSASRSESMERAGSDQRPVAVTVVGHPDGPQPREPPPANSLTPRPIRSIPKPPSAGAPTTPTTRRRVAK-----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. * . * : * * * : :: . * :: .. *. : : * ..:.*..: : . : .*:. ... . .. .:. *. . *. .* . . * . *. .: **: . : :: . : . . : : . * . . :**:*.. .*: :: :* : ::: : *: : : .. . *. * * * :* ..::** : .: * * : * : . . : : *.. .* *. * ... . . .. . . .:....*: ::. : * :. .: .*. . ::: : :. :: :*: :: . ::*::: . ** ** . : * :.* : :: ::. :::* * .. :::*: :: : .:.* *: ::..: :::: . :* : *: . : : . .:.*: :*: ..::. :: *: * .*: : **** * .*: .::.. : . * *. **. :*: ** * :* * * .:. .*: : * . * *. .* * : **:* .*:*: :*:*.*** : ** : :: :*. . * . . *. ..:*.::.:: :: . * : : * . :* ::: :. *.. .* . .... ... . * . . . * :. ..* ..* . . **. .*: :: :* * . *. :::. :::: : .. . .. * . : : *:* .: ::: * : :. : : ** * * ... *:. .. *. . ..: ..: :::: .* : **: * * * . * . .: .* : : :* * ..:: ..: . : :*: : :*. :*:::: ** . :: * :: *.. .* :.: * . : : .. :.. .: . : :** : : . ..: . :: **. *:::* :. * :: : :. *::: *::: . *: . . : *:: *:.: .*. . *. . :: . . *: : . * : * * .::*: :: : :* : *: .* *: :** : .* . : : :: : : . : : : . : .: . ..: * :.: **:.. . . * *: :. : ::: *:. : *:: ::* *. :: . .*. : * * ::: :. . . . . .. . ::*: .: . ... ::: :. .* .* . . ** * . : .:. ..:. . : : * : . * * ..: :* . : : * * : . .* *.: : : :. .: : . . : . ** .. . : :: :. * .:.: .** . *.: . :: . :..:**.. : ::* * *::: **:*. . : * : : *.* *. .. . . : * . . :*:*. : :: ** : *::. ** * . *** * .:. .* * :. * *: * : . : .* : . : ..: :: . : :: .: :.: :. * *. . .:.. .**. . ", "identical_positions": 238, "similar_positions": 675, "identity": "11.75%" }, { "cls_id": "homologset.agr.RGD:1308320", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZM46-1", "uniprot_id": "A0A8I5ZM46_RAT", "id": "A0A8I5ZM46-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSNELDFRSVRLLKNDPVSFQKFPYNNEDEAWKTYLENPLTAATKAIMRVNGDDESVAALSFLY----DYYMGPKEKRILSSSTGG-------------RNDQGKKYYHSMDYEPDLAPLESPTHLMKFLTENVSGSP-----------------------DYTDQLKKNNLLGLEGALPTPGKTSTLPPGPSKLEAGSMDSYLLPTSDMYDNSS----------------------------------------------------------------LNSLFESIHGVPPTQRWQPDSTFKDDPQ---ESLLFP---DILKTSPEAPCPEDYPS---------------------------------------------------------------------------------------------------------LKSDFEYTLGSPKAIHIKAGESPMAYLNKGQFYPVTLRTPAGGKGLSLSSSKVKSVVMIVFDNDKVPVEQLRFWRHWHSRQPTAKQRVIDVADCKENFNTVQHIEEVAYNALSFVWN-VNEEAKVFIGVNCLSTDFSSQKGVKGVPLNLQIDTYDCGAGTERLVHRAVCQIKIFCDKGAERKMRDDERKQFRRKVKCPDSSNNAGIKGCLLSG---------------------------------------------FRGNETTYLRPEADLETQP---------VLFIPNLHFSSLQRPGGVVPSAGHSSSDRLPLKRTCSPFAEEFEPLPSKQ--AKEDDLQRVLLYVRRETEEVFDALMLKTPDLKGLRNAISEKYGFPEENICKVYKKCKRGILVNMDNNIIQH-------YSNHVAFLLDMG---------ELDG-KIQIILKEL-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5FWH3-1", "uniprot_id": "GRHL3_MOUSE", "id": "Q5FWH3-1", "name": "Grainyhead-like protein 3 homolog", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSNELDFRSVRLLKNDPVSFQKFPYSNEDEAWKTYLENPLTAATKAMMRVNGDEESVAALSFLY----DYYMGPKEKRILSSSTGG-------------RNDQGKKFYHSMDYEPDLAPLESPTHLMKFLTENVSGSP-----------------------DYTDQLKKNNLLGLEGVLPTPGKTNTVPPGPSKLEASSMDSYLLPASDIYDNGS----------------------------------------------------------------LNSLFESIHGVPPTQRWQPDSTFKDDPQ---ESLLFP---DILKTSPDPPCPEDYPG---------------------------------------------------------------------------------------------------------LKSDFEYTLGSPKAIHIKAGESPMAYLNKGQFYPVTLRTPAGGKGLALSSSKVKSVVMVVFDNDKVPVEQLRFWRHWHSRQPTAKQRVIDVADCKENFNTVQHIEEVAYNALSFVWN-VNEEAKVFIGVNCLSTDFSSQKGVKGVPLNLQIDTYDCGAGTERLVHRAVCQIKIFCDKGAERKMRDDERKQFRRKVKCPDSSNNAGIKGCLLSG---------------------------------------------FRGNETTYLRPETDLETQP---------VLFIPNLHFSSLQRPGGVVPSAGHSSSDRLPLKRTCSPFAEEFEPLPSKQ--AKEDDLQRVLLYVRRETEEVFDALMLKTPDLKGLRNAISEKYGLPEENICKVYKKCKRGILVNMDNNIIQH-------YSNHVAFLLDMG---------ELDG-KIQIILKEL-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TE85-1", "uniprot_id": "GRHL3_HUMAN", "id": "Q8TE85-1", "name": "Grainyhead-like protein 3 homolog", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSNELDFRSVRLLKNDPVNLQKFSYTSEDEAWKTYLENPLTAATKAMMRVNGDDDSVAALSFLY----DYYMGPKEKRILSSSTGG-------------RNDQGKRYYHGMEYETDLTPLESPTHLMKFLTENVSGTP-----------------------EYPDLLKKNNLMSLEGALPTPGKAAPLPAGPSKLEAGSVDSYLLPTTDMYDNGS----------------------------------------------------------------LNSLFESIHGVPPTQRWQPDSTFKDDPQ---ESMLFP---DILKTSPEPPCPEDYPS---------------------------------------------------------------------------------------------------------LKSDFEYTLGSPKAIHIKSGESPMAYLNKGQFYPVTLRTPAGGKGLALSSNKVKSVVMVVFDNEKVPVEQLRFWKHWHSRQPTAKQRVIDVADCKENFNTVEHIEEVAYNALSFVWN-VNEEAKVFIGVNCLSTDFSSQKGVKGVPLNLQIDTYDCGLGTERLVHRAVCQIKIFCDKGAERKMRDDERKQFRRKVKCPDSSN-SGVKGCLLSG---------------------------------------------FRGNETTYLRPETDLETPP---------VLFIPNVHFSSLQRSGGAAPSAGPSSSNRLPLKRTCSPFTEEFEPLPSKQ--AKEGDLQRVLLYVRRETEEVFDALMLKTPDLKGLRNAISEKYGFPEENIYKVYKKCKRGETSLLHPRLSRHPPPDCLECSHPVTQVRNMGFGDGFWRQRDLDSNPSPTTVNSLHFTVNSE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B5G5-1", "uniprot_id": "A0A8M2B5G5_DANRE", "id": "A0A8M2B5G5-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTKEIEALMVQ--QNESFSHIR-TYESYVMDYWTNMDSGNLSKTKPRLAS---DEDLATLNLLY----DACKPSKEQKMTSCARES-------------SMYKSMER-TANSSSPELAPLEN-AHIMKFLSENMSFNP-----------------------SKP----------------------------------STDSY---TTDNYDKQVN---------------------------------------------------------------LNNIFDSLLPQPSQKSWQPDQTFLEATP---EVRIYHIGHNGFGGQTSPVYSDSYSSP------------------------------------------------------------------------------------------------------GRYRNDFQFLLGAPQASQHKTTEIPMVYLNKGQFYPITLQGVDSTAGVPCS--KVKTVIMAVFENDKSPEMQLKYWNHWHARQPTVKQRVIDIADYKEVFSGVSNVEEVAFNALSFIWN-TNEEAKVHIGINSLSTDFSSQKGVKGLPLNLQIDTYDFSSGNNRLIHRAVCQVKIFCDKGAERKMRDEERKRSKRRTKNTADSSNNNCKQALVSS---------------------------------------------SVGKDSTYFKTLDDHVTQP---------VLFIPEMHFSTMQRCG-LVPPVSLEESDRSSLKR-YADANEQSSSPPCKQ--PRR-DEQRVLLYVRRESEEVFDALMLNTPNLKGLKEAISEKYGMQEDTIGKIFKKCKRGIFVNMDDNIIEH-------YSNHSAFLIEIS---------EVIVNHYQVTLMEL-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P13002-6", "uniprot_id": "ELF1_DROME", "id": "P13002-6", "name": "Protein grainyhead", "aln": "MSTSTATTSVITSNELSLSGHAHGHGHAHQLHQHTHSRLGVGVGVGILSDASLSPIQQGSGGHSGGGNTNSSPLAPNGVPLLTTMHRSPDSPQPELATMTNVNVLDLHTDNSKLYDKEAVFIYETPKVVMPADGGGGNNSDEGHAIDARIAAQMGNQAQQQQQQQQQTEHQPLAKIEFDENQIIRVVGPNGEQQQIISREIINGEHHILSRNEAGEHILTRIVSDPSKLMPNDNAVATAMYNQAQKMNNDHGQAVYQTSPLPLDASVLHYSGGNDSNVIKTEADIYEDHKKHAAAAAAAAGGGSIIYTTSDPNGVNVKQLPHLTVPQKLDPDLYQADKHIDLIYNDGSKTVIYSTTDQKSLEIYSGGDIGSLVSDGQVVVQAGLPYATTTGAGGQPVYIVADGALPAGVEEHLQSGKLNGQTTPIDVSGLSQNEIQGFLLGSHPSSSATVSTTGVVSTTTISHHQQQQQQQQQQQQQQQQQHQQQQQHPGDIVSAAGVGSTGSIVSSAAQQQQQQQLISIKREPEDLRKDPKNGNIAGAATANGPGSVITQKILHVDAPTASEADRPSTPSSSINSTENTESDSQSVSGSESGSPGARTTATLEMYATTGGTQIYLQTSHPSTASGAGGGAGPAGAAGGGGVSMQAQSPSPGPYITANDYGMYTASRLPPGPPPTSTTTFIAEPSYYREYFAPDGQGGYVPASTRSLYGDVDVSVSQPGGVVTYEGRFAGSVPPPATTTVLTSVHHHQQQQQQQQQHQQQQQQQQHHQQQQHHSQDGKSNGGATPLYAKAITAAGLTVDLPSPDSGIGTDAITPRDQTNIQQSFDYTELCQPGTLIDANGSIPVSVNSIQQRTAVHGSQNSPTTSLVDTSTNGSTRSRPWHDFGRQNDADKIQIPKIFTNVGFRYHLESPISSSQRREDDRITYINKGQFYGITLEYVHD-AEKPIKNTTVKSVIMLMFREEKSPEDEIKAWQFWHSRQHSVKQRILD-ADTKNSVGLVGCIEEVSHNAIAVYWNPLESSAKINIAVQCLSTDFSSQKGVKGLPLHVQIDTFED-PRDTAVFHRGYCQIKVFCDKGAERKTRDEERRAAKRKMTATGRKKLDELYHPVTDRSEFYGMQDFAKPPVLFSPAEDMEKVGQLGIGAATGMTFNPLSNGNSNSNSHSSLQSFYGHETDSPDLKGASPFLLHGQKVATPTLKFHNHFPPDMQTDKKDHILDQNMLTSTPLTDFGPPMKRGRMTPPTSERVMLYVRQENEEVYTPLHVVPPTTIGLLNAIENKYKISTTSINNIYRTNKKGITAKIDDDMISF-------YCNEDIFLLEVQ---------QIEDDLYDVTLTELPNQ----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . : ::: . : : . :. . * . : ::. * : * .*: .: ..: . . . ...: . *. : :: . * .* . . : :.* ::. ..:: *: : * : : : . . . . .. .. . .*.: * :* : : : :.*:****** :**. . . . .**:*:* :* ::* * ::: *..**:** :.***::* ** *: .. * :***:.**::. ** :..**: *.::.*************:**::****:: :.**. **:*:********* **:**: :*: . . .. : . .:. : ::. . * . :*. :: .::: . * ...:: :. : * *: :**:****:*.***: .* : .* ** :**.:** : .* ::::. *:* :. : . .: : :: :: : .* ", "identical_positions": 117, "similar_positions": 194, "identity": "8.63%" }, { "cls_id": "homologset.agr.RGD:1308321", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9DAU9-1", "uniprot_id": "ZN654_MOUSE", "id": "Q9DAU9-1", "name": "Zinc finger protein 654", "aln": "MAEEESDQEAERLGEELVAIVESPPGPVGLLAAGDGRGGAGGGGCGGGVGISSRDYCRRFCQVVEDYAGRWQVPLPQLQVLQTALCCFTSASASFPDECEHVQYVLSSLAVSFFELLLFFGRDEFYEEPLKDILGSFQECQNHLRRYGNVNLELVTRIIKDGGPWEDPVLQAVLKAQPASQEIVNKYLSSENPLFFELRARYLIACERIPEAMALIKSCINHPEISKDLYFHQALFTCLFMSPVEDQLFREHLLKTDCKSGIDIICNTEKEGKTLLALQLCESFLIPQLQNGDMYYIWELIFLWSKLQLKSNPSKQVFVDQCYQLLRTATNVRVIFPFMKIIKDEVEEEGLQICVEICGCALQLDLHDDPETKCLIYKTIAHFLPNDLEIVRVCALSVFFLERSLDAYHTVEELYRRPDEEYSEGMSTVQNRVRFELLPILKKGLFFDPEFWNFVMIKKNCVALLRDKSAVKLLNENTLENPSSSLKKRVDQQSVEE------DQSTGETDPDDASVVQPKGQVNVKRSLSALNTSKVDHSVPRHRCMLCNKEFLGGHIVRHAQAHQKKGSFACVICGRKFRNRGLMQKHLKNHVKKIQRQQIATAQQDDPEVITLEEINGSKSLISFENGNSNTKGLEIETLTASSERNKEVIREHMAEFIKIPIAIPENAIENIIENGKPDASFNNISESLPQCDDDYEEEENE--DDYEDDYDLNQETSVLHKINGTVCHPKDVYATDQEGNFKCPALGCVRIFKRIGFLNMHARTVHPTDLNVRQTVMKWSKGKCKFCQRQFEDSQHFIDHLNRHSYPNVYFCLHFNCNESFKLPFQLAQHTKSHRIFQAQCSFPECHELFEDLPLLYEHEAQHYLSKTPESSAQLSEVVPN--------HQEIDPFSNENQTIHHPVSTSKSRKYSTEPKTYIDTMEKKTDSLVHNGNEHSDDTVSNISLIDQKMPAIEPNPENTHSTTDLVNGHSEIEQTPLVTSDPTLKIDINRNRTENGSILPSVESQEHSALSVSQAPSKPNLTSEQTSYGLIVTKPFVRPLPPSYLDERYLSMPKRRKFLTDIVDACSDQDNMYKKPVKRLRCGKCLTTYCNAEALEAHLAQKKCQTLFGFDSDDESA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZMK5-1", "uniprot_id": "D3ZMK5_RAT", "id": "D3ZMK5-1", "name": "", "aln": "MAEEESDQEAERLGEELVAIVESPPGPVGLRAAGDGRGGASGSGSGGGVGISSRDYCRRFCQVVEDYAGRWQVPLPQLQVLQTALCCFTSASTSFPDECEHVQYVLSSLAVSFFELLLFFGRDEFYEEPLKDILGSFQECQNHLRRYGNVNLELVTRIIKDGGPWEDPVLQAVLKAQPASQEIVNKYLSSENPLFFELRARYLIACERIPEAMALIKSCINHPEISKDLYFHQALFTCLFMSPVEDQLFREHLLKTDCKSGIDIICNTEKEGKTLLALQLCESFLIPQLQNGDMYYIWELIFIWSKLQLKSNPSKQVFVDQCYQLLRTATNVRVIFPFMKIIKDEVEEEGLQICVEICGCALQLDLHDDPETKCLIYKTIAHFLPNDLEIVRVCALSVFFLERSLDAYQTVEELYRRPDEEYSEGTSTVQNRVRFELLPILKKGLFFDPEFWNFVMIKKNCVALLRDKSAMKLINENTLENSAGSLKNRVEQQSVEDGLDTLTDLSTGETDPDGTSVMQRKGQVNSKRSLSVLNTSKVDHSVPRHRCMLCNKEFLGGHIVRHAQAHQKKGSFSCVICGRKFRNRGLMQKHLKNHVKKIQRQQIATAQQDDPEIITLEEINGSKSSISFENGNSNTKSLEIETLTASSERNKEVTREHMAEFIKIPIAMPENAMENIVENGRPDTSFNNISESLSQCDDDYEEEENE--DNYEDDYDLNQETSVLHKINGTVCHPKDVYATDQEGNFKCPALGCVRIFKRIGFLNMHARTVHPTDLNVRQTVMKWSKGKCKFCQRQFEDSQHFIDHLNRHSYPNVYFCLHFNCNESFKLPFQLAQHTKSHRIFQAQCSFPECHELFEDLPLLYEHEAQHYLSKTPESSAQLGEVVPN--------HQNIDPFSNENQTIHQPVSTSKSRKDSTEPKTCIDTMEKKTDSLVQNGNEHSDDSVSNISLIDQKMPAIEPNPENNHSPTDLVNGHSEIEQMPLVTSDATLKIDINRNGTENGSVIPNVISQEHSALSVSQAPSKPNLTSEHTSYGLILTKPFVRPLPPSYLDERYLSMPKRRKFLTDIVDACSDQDNMYKKPVKRLRCGKCLTTYCNAEALEAHLAQKKCQTLFGFDSDDESA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8IZM8-1", "uniprot_id": "ZN654_HUMAN", "id": "Q8IZM8-1", "name": "Zinc finger protein 654", "aln": "MAEEESDQEAERLGEELVAIVESPLGPVGLRAAGDGRGGAGSGNCGGGVGISSRDYCRRFCQVVEDYAGRWQVPLPQLQVLQTALCCFTTASASFPDECEHVQYVLSSLAVSFFELLLFFGRDEFYEEPLKDILGSFQECQNHLRRYGNVNLELVTRIIRDGGPWEDPVLQAVLKAQPASQEIVNKYLSSENPLFFELRARYLIACERIPEAMALIKSCINHPEISKDLYFHQALFTCLFMSPVEDQLFREHLLKTDCKSGIDIICNAEKEGKTMLALQLCESFLIPQLQNGDMYCIWELIFIWSKLQLKSNPSKQVFVDQCYQLLRTATNVRVIFPFMKIIKDEVEEEGLQICVEICGCALQLDLHDDPKTKCLIYKTIAHFLPNDLEILRICALSIFFLERSLEAYRTVEELYKRPDEEYNEGTSSVQNRVRFELLPILKKGLFFDPEFWNFVMIKKNCVALLSDKSAVRFLNESTLENNAGNLKRTEEQQGLDEGFDSLTDQSTGETDPDDVSGVQPKGHINTKKNLTALSTSKVDHNVPRHRCMLCNKEFLGGHIVRHAQAHQKKGSFACVICGRKFRNRGLMQKHLKNHVKKIQRQQIAAAQQDDQEVTALEEINCSSSSISFENGNSDSKDLEVETLTASSEGNKEVIPEHVAEFIEIPISVPEDVIENVIENGSPNNSLNNVFKPLTECGDDYEEEEDEEGDYEEDDYDLNQETSVIHKINGTVCHPKDIYATDQEGNFKCPALGCVRIFKRIGFLNKHAMTVHPTDLNVRQTVMKWSKGKCKFCQRQFEDSQHFIDHLNRHSYPNVYFCLHFNCNESFKLPFQLAQHTKSHRIFQAQCSFPECHELFEDLPLLYEHEAQHYLSKTPESSAQPSETILWDVQTDSNPNQEKDSSSNEKQTISLPVSTSKSRKESTEPKTCIESMEKKTDSLVQNGNERSDDTVSNISLIDQKMPDIEPNSENNCSSSDIVNGHSEIEQTPLVSSDPALKIDTNRIRTENGSILPSVVPQEHNTLPVSQAPSKPNLTSEHTSYGLILTKPYVRPLPPSYLDERYLSMPKRRKFLTDRVDACSDQDNVYKKSVKRLRCGKCLTTYCNAEALEAHLAQKKCQTLFGFDSDDESA", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "************************ ***** *********.....********************************************:**:******************************************************************:***********************************************************************************************************:******:******************** ******:*******************************************************************:*******************:*:****:*******:**:******:******.** *:************************************* ****::::**.**** :..**. :**.::: * ********..* :* **::* *:.*:.*.******.*******************************:*******************************:***** *: :***** *.* ********::*.**:******** **** **:****:***::**:.:**::*** *: *:**: :.*.:*.*******:* * ************:************:*************************** ** *************************************************************************************************************** .*.: :*: *. ***:*** ********* ****** *::*********:****:***:************ ****.**. *.:*:********* ***:**.:**** ** *****::*.* .***.:*.*************:******:***:************************* *********:***.*****************************************", "identical_positions": 963, "similar_positions": 106, "identity": "85.37%" }, { "cls_id": "homologset.agr.RGD:1308322", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZVU3-1", "uniprot_id": "D3ZVU3_RAT", "id": "D3ZVU3-1", "name": "Myogenic factor", "aln": "-------MDMTDSCQFSPSEYF--YDGSCIP----------SPEDEFG-------DQFEPRVAAFG---------------------------AHKAKLQG----------------SDD------EEHVRAP---TGHHQAGHCLMWACKACKRKSTTMDRRKAATMRERRRLKKVNQAFETLKRCTTTNPNQRLPKVEILRNAIRYIESLQELLREQVENYYSLPGQSCSQPTSPTSNCSDGMPECNSPVWSRKNSSFDSIYCPDVSNACASD-KSSLSSLDCLSSIVDRITSAEPSELALQDTASLSPAASTNSQPATPGSSSSRLIYHVL--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P24699-1", "uniprot_id": "MYF5_MOUSE", "id": "P24699-1", "name": "Myogenic factor 5", "aln": "-------MDMTDGCQFSPSEYF--YEGSCIP----------SPEDEFG-------DQFEPRVAAFG---------------------------AHKAELQG----------------SDD------EEHVRAP---TGHHQAGHCLMWACKACKRKSTTMDRRKAATMRERRRLKKVNQAFETLKRCTTTNPNQRLPKVEILRNAIRYIESLQELLREQVENYYSLPGQSCSEPTSPTSNCSDGMPECNSPVWSRKNSSFDSIYCPDVSNACAAD-KSSVSSLDCLSSIVDRITSTEPSELALQDTASLSPATSANSQPATPGPSSSRLIYHVL--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P13349-1", "uniprot_id": "MYF5_HUMAN", "id": "P13349-1", "name": "Myogenic factor 5", "aln": "-------MDVMDGCQFSPSEYF--YDGSCIP----------SPEGEFG-------DEFVPRVAAFG---------------------------AHKAELQG----------------SDE------DEHVRAP---TGHHQAGHCLMWACKACKRKSTTMDRRKAATMRERRRLKKVNQAFETLKRCTTTNPNQRLPKVEILRNAIRYIESLQELLREQVENYYSLPGQSCSEPTSPTSNCSDGMPECNSPVWSRKSSTFDSIYCPDVSNVYATD-KNSLSSLDCLSNIVDRITSSEQPGLPLQDLASLSPVASTDSQPATPGASSSRLIYHVL--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P22816-1", "uniprot_id": "MYOD_DROME", "id": "P22816-1", "name": "Myogenic-determination protein", "aln": "MTKYNSGSSEMPAAQTIKQEYHNGYGQPTHPGYGFSAYSQQNPIAHPGQNPHQTLQNFFSRFNAVGDASAGNGGAASISANGSGSSCNYSHANHHPAELDKPLGMNMTPSPIYTTDYDDENSSLSSEEHVLAPLVCSSAQSSRPCLTWACKACKKKSVTVDRRKAATMRERRRLRKVNEAFEILKRRTSSNPNQRLPKVEILRNAIEYIESLEDLLQESST---TRDGDNLAPSLSGKS-CQSDYLSSYAGAYLEDKLSFYNKHMEKYGQFTDFDGNANGSSLDCLNLIVQSINKSTTSPIQNKATPSASDTQSPPSSGATAPTSLHVNFKRKCST", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ..* .**. * . * .* . * ::* .*. *.* * *:*: .*: :*** ** :. :.: ** *******:**.*:**************:***:*** *** *::****************.*****::**:*. : *:. : . * .* *... .. : .: ... :* . : . .: * : . ******. **: *..: . : : .* * . *. *. **. .* : : ", "identical_positions": 102, "similar_positions": 76, "identity": "30.36%" }, { "cls_id": "homologset.agr.RGD:1308323", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9DBK7-1", "uniprot_id": "UBA7_MOUSE", "id": "Q9DBK7-1", "name": "Ubiquitin-like modifier-activating enzyme 7", "aln": "-------------MDEELYSRQLYVLGLPAMQRIQEAKVLLCGLQGLGAEVAKNLVLTGVGSLTLHDPHPTCWADLAAQCFLSEESLGRNRAEASQAQLAQLNEAVQISVHSGDITEDLLQGFQVVVLTDSK-LEDQLKVGPLCHKHGVRFLMAETRGLVGRLFCDFGEDFTVLDPTEVEPMTAAIQDISQGFPGIVTLRGDTKRHSFHDGDLVIFSDIEGMVELNSCSPQSVRVQKDGSLEIGDTTTFSRYLRGGVVTEVKRPKTVRHKPLDIALLQPH-----VVAQNTQEVQRAHCLHQAFHVLHKFQQLHG-RLPKPWDPDDAETVVELAQDLEPLKGTEEE----SLDEALLRTIALSSAGTLSPMAAIMGGVAAQEVLKAISRKFMPLDQWLYFDALECLPEDETLLPSPEDCQPRNCRYDGQIAVFGTDLQEKLSDQHYLLVGAGAIGCEMLKVFALVGLGVRANGGVTVADMDYIERSNLSRQFLFRPKDVRRPKAEVAAAAAHRLNPDLR--ATPYTCPLDPTTEDIYDDSFFSRVNGVVAALDSFQAR--------------------------HYVAARCTHYLKPLLEAGTQGTWGSASVFVPYVTEAYRGPASDAASEDAPYPVCTLRHIPSSMEHSVQWAQDQFEGLFRLSTETINCYQQT---CTS-LSATDRTETLALLQQVMGVLRTR-PQTWQDCVVWALGHWQLCFHD------------KVLEGGTQFSSGSNKCPHPLQFDPNHDMHFLYVLAAANLYARMHGLPGSQ-----SQPALRELLTR--LLESDSRPQNLFS-----------AEHGQE--QLKELQETLDDWRKGPP---LKPVLFVKDDDSNFHVDFVVAATDLRCQNYGILPVNHARIKQIVGRIIPAIATSTAVVAGLLGLELYKVVSGLRSHGTFRHSYLHLAENHFIRSAPSAPAVQSFRDLKWT-CWDRLKVPAV---QPERTLKSLLAHLQEEHGLKVEMLLHHQALLYSSGWSSEKQAQHLCLRVTELVQHVTGWKPKPGLKVLVFELSCE-GEEEE-MAFPPLHYEL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6G652-1", "uniprot_id": "A0A8I6G652_RAT", "id": "A0A8I6G652-1", "name": "", "aln": "-------------MDEELYSRQLYVLGLPAMQRIREAKVLLCGLQGLGAEVAKNLVLMGVGSLTLHDPHPTCWADLAAQFFLSEESLGRSRAEASQPQLAQLNEAVQISVHRGDITEDLVRGFQVVVLTDSK-LEDQLNMGALCHKNRVYFLMAETRGLVGRLFCDFGEDFTVVDPTEVEPTSAAIQDISQGSPGIVTLRGGSKRPSFYDGDLVMFSDIEGMVELNSHSPQPVRVQKDGSLEIGDTTTFSRYLRGGVVTEVKRPKTVKHKPLDIALLQPC-----MVVQNTQEIQRAHCLHQTFHALHKFQQLHG-RLPKPWDPDDAETVVWLAQDLEPLKGAKEE----SLDEALLRTIALSSAGSLSPMAAILGGVAAQEVLKAVSGKFMPLDQWLYFDALECLPEDETLLPSPEDCHPRNCRYDGQIAVFGTGFQEKLSYKHYLLVGAGAIGCEMLKGFALVGLGVRDNGGVTIADMDHVERSNLSRQFLFRPKDTGRPKAEVAAEAAHRLNPDLQ--VTSHTCPLDPTTEDIYDDDFFSRVDGVVAALDSFQARESLTESQVPCPRLWQPHPIPSTLLPGHYVAARCTHYLKPLLEAGTQGTRGSASVFVPYVTEVYKGPTS---AEEAPYPVCTLRHFPSTVEHSLQWAQDEFEGLFRLSAETINDYQQT---CTSSLLGTDGTGILALLQQVMGVLRTR-PQTWQDCVVWALGHWQLCFRDNIVELLRKFPSDKVLEDGTLFWSGSKKCPHPLQFDPNQDTHFLYVLAAANLYARMHGLPGSQ-----SQTALRELLTLTLLQEPDSMPQNLFS-----------AEFGQE--QLKELQETLDDWNKGPP---LKPVLFGKDDSSNFHEDFVVAATDLRCQNYGILPVNRARIKQTIGRIIPAIATSTAVVAGLLGLELYKVVSGPRPLGTFRHSYLHLAENHFIRSAPSAPAMQSFHHLEWT-CWHRLTVPAG---QPERTLESLLAHLQEEHGLTVRMLLHDQALLYSSGWPFEKQAQHLGLRTSS-----AGDRP---------ETQAW-AESSG-V----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P41226-1", "uniprot_id": "UBA7_HUMAN", "id": "P41226-1", "name": "Ubiquitin-like modifier-activating enzyme 7", "aln": "----MDALDASKLLDEELYSRQLYVLGSPAMQRIQGARVLVSGLQGLGAEVAKNLVLMGVGSLTLHDPHPTCWSDLAAQFLLSEQDLERSRAEASQELLAQLNRAVQVVVHTGDITEDLLLDFQVVVLTAAK-LEEQLKVGTLCHKHGVCFLAADTRGLVGQLFCDFGEDFTVQDPTEAEPLTAAIQHISQGSPGILTLRKGANTHYFRDGDLVTFSGIEGMVELNDCDPRSIHVREDGSLEIGDTTTFSRYLRGGAITEVKRPKTVRHKSLDTALLQPH-----VVAQSSQEVHHAHCLHQAFCALHKFQHLHG-RPPQPWDPVDAETVVGLARDLEPLKRTEEEPLEEPLDEALVRTVALSSAGVLSPMVAMLGAVAAQEVLKAISRKFMPLDQWLYFDALDCLPEDGELLPSPEDCALRGSRYDGQIAVFGAGFQEKLRRQHYLLVGAGAIGCELLKVFALVGLGAGNSGGLTVVDMDHIERSNLSRQFLFRSQDVGRPKAEVAAAAARGLNPDLQ--VIPLTYPLDPTTEHIYGDNFFSRVDGVAAALDSFQAR--------------------------RYVAARCTHYLKPLLEAGTSGTWGSATVFMPHVTEAYRAPASAAASEDAPYPVCTVRYFPSTAEHTLQWARHEFEELFRLSAETINHHQQA---HTS-LADMDEPQTLTLLKPVLGVLRVR-PQNWQDCVAWALGHWKLCFHYGIKQLLRHFPPNKVLEDGTPFWSGPKQCPQPLEFDTNQDTHLLYVLAAANLYAQMHGLPGSQ-----DWTALRELLKLLPQPDPQQMAPIFASNLEL---ASASAEFGPE--QQKELNKALEVWSVGPP---LKPLMFEKDDDSNFHVDFVVAAASLRCQNYGIPPVNRAQSKRIVGQIIPAIATTTAAVAGLLGLELYKVVSGPRPRSAFRHSYLHLAENYLIRYMPFAPAIQTFHHLKWT-SWDRLKVPAG---QPERTLESLLAHLQEQHGLRVRILLHGSALLYAAGWSPEKQAQHLPLRVTELVQQLTGQAPAPGQRVLVLELSCE-GDDED-TAFPPLHYEL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P22515-1", "uniprot_id": "UBA1_YEAST", "id": "P22515-1", "name": "Ubiquitin-activating enzyme E1 1", "aln": "MSSNNSGLSAAGEIDESLYSRQLYVLGKEAMLKMQTSNVLILGLKGLGVEIAKNVVLAGVKSMTVFDPEPVQLADLSTQFFLTEKDIGQKRGDVTRAKLAELNAYVPVNVLDSLDDVTQLSQFQVVVATDTVSLEDKVKINEFCHSSGIRFISSETRGLFGNTFVDLGDEFTVLDPTGEEPRTGMVSDIEPD--GTVTMLDD-NRHGLEDGNFVRFSEVEGLDKLNDGTLFKVEVLGPFAFRIGSVKEYGEYKKGGIFTEVKVPRKISFKSLKQQLSNPE-----FVFSDFAKFDRAAQLHLGFQALHQFAVRHNGELPRTMNDEDANELIKLVTDLSVQQPEVLG-EGVDVNEDLIKELSYQARGDIPGVVAFFGGLVAQEVLKACSGKFTPLKQFMYFDSLESLPDPKNFPRNEKTTQPVNSRYDNQIAVFGLDFQKKIANSKVFLVGSGAIGCEMLKNWALLGLGSGSDGYIVVTDNDSIEKSNLNRQFLFRPKDVGKNKSEVAAEAVCAMNPDLKGKINAKIDKVGPETEEIFNDSFWESLDFVTNALDNVDAR--------------------------TYVDRRCVFYRKPLLESGTLGTKGNTQVIIPRLTESYSSSRD---PPEKSIPLCTLRSFPNKIDHTIAWAKSLFQGYFTDSAENVNMYLTQPNFVEQTLKQSGDVKG--VLESISDSLSSK-PHNFEDCIKWARLEFEKKFNHDIKQLLFNFPKDAKTSNGEPFWSGAKRAPTPLEFDIYNNDHFHFVVAGASLRAYNYGIKSDDSNSKPNVDEYKSVIDHMIIPEFTPNANLKIQVNDDDPDPNANAANGSD--EIDQLVSSLPDPSTLAG-FKLEPVDFEKDDDTNHHIEFITACSNCRAQNYFIETADRQKTKFIAGRIIPAIATTTSLVTGLVNLELYKLIDNKTDIEQYKNGFVNLALPFFGFSEPIASPKGEYNNKKYDKIWDRFDIKG------DIKLSDLIEHFEKDEGLEITMLSYGVSLLYASFFPPKKLKERLNLPITQLVKLVTKKDIPAHVSTMILEICADDKEGED-VEVPFITIHL-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "A0ACD6B740-1", "uniprot_id": "A0ACD6B740_DANRE", "id": "A0ACD6B740-1", "name": "E1 ubiquitin-activating enzyme", "aln": "--------MAQGDIDEGLYSRQLYVIGHDAMRRMGKADVLIAGMRGLGVEIAKNVILAGVRTVTIQDEGVVEWRDLSSQFYLKEADLGQNRALCSEKQLSSLNAYVKVSASTNKLDENFLSKFQVVVLTSSP-LDEQLRVGAFCHSNNIKFIVADTRGLCGQLFCDFGESFEVIDTNGDPPVSAMISHISKENPGVVNCTDE-ESHEFTDGMFVTFSEVQGMTELNNYGPVEIKVKDSYSFSICDTSNFSDYVKCGVATEVKQPEILSFKPLNVALDEALRDPGLVEMTDYGKTKRHLSLHLAFQALHKFTQKYS-RTPHPRSQADAEVLLTITKELCTEA------KFDKLDEDAVRNLSLVASGDLAPVNAFIGGLAAQEVVKACSGKFTPLRQWLYFDALECLPQEEGGVLSEDACAPRDSRYDGQIAVFGSDFQNKLKKQKYFLVGAGAIGCELLKNFALIGLGAGEGGSITVTDMDSIERSNLNRQFLFRSQDIGRPKSEAAAEAVKEMNPFMN--IIAQQNRVCAETEEVYTHSFYTGLDGVAAALDNVDAR--------------------------VYLDQCCVRNKKPMLEGGTLGSKGHTMVVVPRLTESYGRSSS---GGQKAIPICTLKNFPHRIEHTLQWARDHFEGLFKQTAQNVNNFLSDPGFVDRTVAR-GDVEAVEMLEGVYRSLSDDWPENWKDCISWARRQWETLYNNHIRQLLHCFPPDQLTSSGLPFWMGAKRCPHALTFDTNNATHMDFIIAAANLYAQIFGITGSR-----NRADIQTVLQGVKVPEFTPKSSVKIAVTDQQLNEENEERKEEDKVKLGMLKEQLSKLQLRDRSFRMHPQDFEKDDDSNFHMDYIVAASNLRAENYDIPTADRHKSKLIAGRIIPAIATTTAAIAGLMCLELYKLVQGHSKITSYRNAYINLATQYFVFSQPCPAPTFTVAGQRYS-LWDDFPVQGCREGQEEMTLEELLKHIEEKHKLKISGLYYGPAVLYSDLS---NHSDRMKLSISDLVRLATKHEVADHQ--QMLEIIPSFEEDEDCLTVPPIRYLLR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :** ********:* ** :: : **: *::***.*:***::* ** ::*: * . **::* *.* .: :.*. :. *:.** * : . . : ***** * : *::::.:. :**. : *: ::**** *. * *:*:.* * *.. * :. :..*. * :. : : ** :* ** ::*: :**. :.* :: * ... :. * : * **** *. : .*.*. * :. . . : .: ** * .**:* :. . *:. . **: :: :. :* ::* :: :: : * :. : *::*.:.****:** * ** ** *::***:*:.**: . . ..***.****** .:*:*: .: :***:******:** :**:*** .* :.:.* * :*:***.******.:* : *:*.** *. :** :. . : . **.:: ..*: :: *. ***..:** *: *. **:**.** *: * : *.:* :** * . . : . *:**:: :* :*:: **: *: * :::.:* . : . :*: : * *..::**: ** .:: :. ..* * *.::.* .* ** : *: :::*.*.* * .*: .. . : :: : . : : * . * :.* * ***.:*.* :::.*.:. *.:** * ..:: : * *:*******:*: ::**: *****::.. :::.:::** .: * ... .: *. : : . : .*..*: *:::.. * : * : ::**: : ::: * :. : * : . ", "identical_positions": 260, "similar_positions": 315, "identity": "24.16%" }, { "cls_id": "homologset.agr.RGD:1308324", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4A8H3-1", "uniprot_id": "D4A8H3_RAT", "id": "D4A8H3-1", "name": "Ubiquitin-like modifier-activating enzyme 6", "aln": "MERSEPLAVLSCEEASCSSWGACGASKNLPTMTTESLEIDDGLYSRQRYVLGDTAMQKMAKSCVFLSGMGGLGVEIAKNLVLAGIKALTIHDTKKCQAWDLGTNFFLCEDDVVNERNRAEAVLHRVAELNPYVQVSSSSAPFDETTDLSFLEKYQCVVLTETKLTLQKKINNFCHSHCPPIKFISTDVHGIWSRLFCDFGDEFEVSDTTGEEPKEIFISNITQANPGIVTCLENHPHKLETGQFLTFREINGMAGLNGSVQQITVISPFSFSIGDTTELDPYLHGGIAVQVKTPKIFNFEPLESQIKHPKCLIADFSKPEAPLQIHVAMLALDQFQENYSRKPNIRCQQDSDELLKLTICISETLEEKPEVNADIVHWLSWTAQGFLPPLAAAVGGVASQEVLKAVTGKFSPLCQWLYLEAADTVESLGNLGHEEFLPRGDRYDAFRACIGNTLCQKLQNLNIFLVGCGAIGCEMLKNFALLGVGTGREKGMVTVTDPDLIEKSNLNRQFLFRPHHIQKPKSYTAAEATLKINPQLKIDAHLNKVCPATESTYSDEFYNKQDIVITALDNVEARRYVDSRCLANLRPLLDSGTMGTKGHTEIIVPQLTESYNSHRDPPEEEIPFCTLKSFPAAVEHTIQWARDKFESSFSHKPSLFNKFWQAYPSAEDVLQKIQNGQSLEGCFQVIKLLSRRPRMWSQCVELARLKFEKYFNHKALQLLHCFPLDTRLKDGSLFWQSPKRPPSPIKFDLNEPLHLSFLQNAAKLYATVYCIPFSEKDLSVDSLMDILSEVKIQEFKPSNKVVQTDETARKPD--HVPVSSEDERNAVFQLEKALSSNKATKSDLQMAVLSFEKDDDSNGHIDFITAASNLRAKMYNIEPADRFKTKRIAGKIIPAIATSTAAVSGLVALEMIKVAGGYPFDAYKNCFLNLAIPIIVFTETSEVRKTEIRNGISFTIWDRWTVHGKEDFTLSDFINAVKEKYGIEPTMVVQGVKMLYVPVMPGHAKRLKLTMHKLVKPSTEKKYVDLTVSFAPDADGDEDLPGPPVRYYFSHDTDE----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C7R4-1", "uniprot_id": "UBA6_MOUSE", "id": "Q8C7R4-1", "name": "Ubiquitin-like modifier-activating enzyme 6", "aln": "MERSEPLAVLSCEEASCSSWGACGASKNLPTMTTESLEIDDGLYSRQRYVLGDTAMQKMAKSCVFLSGMGGLGVEIAKNLVLAGIKALTIHDTKKCQAWDLGTNFFLCEDDVVNERNRAEAVLHRIAELNPYVQVSSSSAPLDETTDLSFLEKYQCVVLTEIKLTLQKKINNFCHSHCPPIKFISADVHGIWSRLFCDFGDEFEVSDTTGEEPKEIFISNITQANPGIVTCLESHPHKLETGQFLTFREIHGMTGLNGSVQQITVISPFSFSIGDTTKLDPYLHGGIAVQVKTPKTFCFEPLESQIKHPRCLIADFSKPEAPLEIHLAMLALDQFQENYNRKPNIRCQQDSDELLKLTVSINETLEEKPEVNADIVHWLSWTAQGFLPPLAAAVGGVASQEVLKAVTGKFSPLCQWLYLEAADTVESLGNPGHEEFLPRGDRYDAIRACIGNTLCQKLQNLNIFLVGCGAIGCEMLKNFALLGVGTGREKGMVTVTDPDLIEKSNLNRQFLFRPHHIQKPKSYTAAEATLKINPQLKIDAHLNKVCPATESIYSDEFYTKQDIIITALDNVEARRYVDSRCLANLRPLLDSGTMGTKGHTEIIVPQLTESYNSHRDPPEEEIPFCTLKSFPAAIEHTIQWARDKFESSFSHKPSLFNKFWQAYPSAEDVLQKIQNGQSLEGCFQVIKLLSRRPRIWSQCVELARLKFEKYFNHKALQLLHCFPLETRLKDGSLFWQSPKRPPSPIKFDLNEPLHLSFLQSAAKLYATVYCIPFSEKDLSVNSLMDILSEVKIEEFKPSNKVVQTDETARKPD--HVPVSSEDERNAVFQLEEALSSNKATKSDLQMTVLSFEKDDDRNGHIDFITAASNLRAKMYSIEPADRFKTKRIAGKIIPAIATSTAAVSGLVALEMIKVAGGYPFDAYKNCFLNLAIPIIVFTETSEVRKTEIRNGISFTIWDRWTVHGKEDFTLSDFINAVKENYGIEPTMVVQGVKMLYVPVMPGHAKRLKLTMHKLVKPSTEKKYVDLTVSFAPDADGDEDLPGPPVRYYFSHDTNE----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AVT1-1", "uniprot_id": "UBA6_HUMAN", "id": "A0AVT1-1", "name": "Ubiquitin-like modifier-activating enzyme 6", "aln": "MEGSEPVAAHQGEEASCSSWGTGSTNKNLPIMSTASVEIDDALYSRQRYVLGDTAMQKMAKSHVFLSGMGGLGLEIAKNLVLAGIKAVTIHDTEKCQAWDLGTNFFLSEDDVVNKRNRAEAVLKHIAELNPYVHVTSSSVPFNETTDLSFLDKYQCVVLTEMKLPLQKKINDFCRSQCPPIKFISADVHGIWSRLFCDFGDEFEVLDTTGEEPKEIFISNITQANPGIVTCLENHPHKLETGQFLTFREINGMTGLNGSIQQITVISPFSFSIGDTTELEPYLHGGIAVQVKTPKTVFFESLERQLKHPKCLIVDFSNPEAPLEIHTAMLALDQFQEKYSRKPNVGCQQDSEELLKLATSISETLEEKPDVNADIVHWLSWTAQGFLSPLAAAVGGVASQEVLKAVTGKFSPLCQWLYLEAADIVESLGKPECEEFLPRGDRYDALRACIGDTLCQKLQNLNIFLVGCGAIGCEMLKNFALLGVGTSKEKGMITVTDPDLIEKSNLNRQFLFRPHHIQKPKSYTAADATLKINSQIKIDAHLNKVCPTTETIYNDEFYTKQDVIITALDNVEARRYVDSRCLANLRPLLDSGTMGTKGHTEVIVPHLTESYNSHRDPPEEEIPFCTLKSFPAAIEHTIQWARDKFESSFSHKPSLFNKFWQTYSSAEEVLQKIQSGHSLEGCFQVIKLLSRRPRNWSQCVELARLKFEKYFNHKALQLLHCFPLDIRLKDGSLFWQSPKRPPSPIKFDLNEPLHLSFLQNAAKLYATVYCIPFAEEDLSADALLNILSEVKIQEFKPSNKVVQTDETARKPD--HVPISSEDERNAIFQLEKAILSNEATKSDLQMAVLSFEKDDDHNGHIDFITAASNLRAKMYSIEPADRFKTKRIAGKIIPAIATTTATVSGLVALEMIKVTGGYPFEAYKNCFLNLAIPIVVFTETTEVRKTKIRNGISFTIWDRWTVHGKEDFTLLDFINAVKEKYGIEPTMVVQGVKMLYVPVMPGHAKRLKLTMHKLVKPTTEKKYVDLTVSFAPDIDGDEDLPGPPVRYYFSHDTD-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PY01-1", "uniprot_id": "A0A8M9PY01_DANRE", "id": "A0A8M9PY01-1", "name": "Ubiquitin-like modifier-activating enzyme 6", "aln": "--------------------------------MADSMDIDDSLYSRQRYVLGDSAMHQMAQSTVFVSGMGALGVEIAKNIVLAGVKAVTLHDSKRCEVWDLGTNFFIREEDVNNQKKRVEAVHSRVAELNPYVQVTMSTDVLDESTDLSFLKRYQCVVLTETKLTLQKRINHFCHTQQPPIKFIGCDVFGICSRVFCDFGETFEVSDPTGEESKEIFIQNISQGSPGVVTCMDSRTHGLQTGQSVCLKEINGMTELNGTMHQITVLSPYTFAIGDTSSFQPYTHGGFFRLVKIPKTFSFEKMEQQLSDPRLLTPDFSKPEVPLQLHAIMLALDAFLEQHARLPNIGCLQDSELLLKYTEEISKTLKNKVCINPDLVRCVSRCARGCLFPLAATVGGIASQEVLKALTGKFSPLQQWFYLDALEVVQPLQSLPAEEFSPRGDRYDALRACIGQSLCLKLHKFQVFMVGCGAIGCEMLKNLALLGVGLSRFLGEICITDPDLIEKSNLNRQFLFRPHHIQKPKSTTAAEASLEINPELQIHAHLHKVCPATEDIYSDDFFSRLNVVVTALDNVEARRYVDSRSVSNQKALLDSGTMGTKGHTEIIVPNLTESYNSHRDPPEEEIPFCTLKSFPAVTEHTIQWARDKFESAFAHKPSMYNMFWQSHSSAQSVLQRMMGGESMEGSFQVIKLLSRRPTQWDHCITLARLKFDKYFKRKALQLLHSFPLDTRLKDGSLFWQSPKRPPSPIDFDLSDPLHFGFVVSAARLFAGIYNIPYSEEQLSYEDVSRVLAEVDVPEYKPAEKHIETDETVKKPDQLKITVSSEEEREAISQLQEAINSNLVTPERLCMSPLFFEKDDDTNGHMDFVASASALRARMYAIEAADRLQTKRIAGKIIPAIATSTAAVAGLVSMELIKIAGGYGFELFKNCFFNLAIPVVVLTETAQVKRTQIRDDISFSIWDRWTIFGREDFTLSDFISAVREKYGIEPTMVVHGVKMLYVPVMPGHNKRLKLTMHKLIKPSSGRKYVDLTVSFAPEVDGDEDLPGPPVRYYFSGENESSETA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *::***.***********:**::**:* **:****.**:*****:****:**:*:**:::*:.********: *:** *:::*.*** ::*******:*: *: ::*:******.:******** **.***:**.**::: ******. **.** **:*****: *** *.****.*****.**:*..**:***::.:.* *:*** : ::**:**: ***:::****:**::*:****:.::** ***: ** ** . ** :* *:..*: * ***:**.**::* ***** * *:: * **: * ***: *** : *.:**::* :*.*:*: :* *:* * ****:***:********:******* **:**:* : *:.* . *** ********:*****::** **:::::*:*************:****** .: * : :*************************** ***:*:*:**.:::*.***:****:** *.*:*:.: ::::***************.::* :.**************:***:**************************. *************:*:****::* ***::.**:.***:: .*.*:**.*********** *.:*: ******:***::*******.***: *******************.***.:***:.*: .**:*:* :* **::*::** : : :*:**.: *:**::* ::****.:*** ::.:***:**:*: **::*: ** .* . * *: * ****** ***:**:::** ***:** **.***::**************:**:*:***::*:**::*** *: :****:*****::*:***::*::*:**:.***:******:.*:***** ***.**:*:*********:************* **********:**:: :***********: **************** :.: ", "identical_positions": 657, "similar_positions": 259, "identity": "62.04%" }, { "cls_id": "homologset.agr.RGD:1308326", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LUV8-1", "uniprot_id": "A0ABK0LUV8_RAT", "id": "A0ABK0LUV8-1", "name": "", "aln": "MGVAKSWGGTCSAEPGKRRKMAAVVAMDTQLMLGVGLIEKDTNGEVLWVWCYPSTTASLRNLLLRKCCLTDENKLLHPFVFGQYRRTWFYVTTVEVPDSSVLKKVTHFSIVLTAKDFNPEKYAAFTRILCRIYLKYGSPVKMMESYIAVLTKGICQSEENGSFLSRDFDGRKAYLAGSIKDIVSQFGMETIILHTALMLKKRIVVYHPKIEAVQEFTRTLPALVWHRQDWSILHSYMHLHAEELEGLQMCTGYIAGFVDLEVSNRPDLYDVFVNLADSEIIIAPLAKEAMTMGKLHKEIGQLIVQSAEDPEKSDSQVIQDIALKTKEIFTHLAPFSEASDAG-KVFLNVEALKQKRFPPATENFLYHLAAAEQMLKADSYFIHGSLSSPLGAALLSVRLRAPGTVGTEASLLHKCCWEP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D8N2-1", "uniprot_id": "DEN10_MOUSE", "id": "Q9D8N2-1", "name": "DENN domain-containing protein 10", "aln": "--------------------MAAVVAMDTQLMLGVGLIEKDSNGEALWVWCYPSTTASLRNLLLRKCCLTDENKLLHPFVFGQYRRTWFYVTTVEVPDSSVLKKVTHFSIVLTAKDFNPEKYAAFTRILCRIYLKYGSPVKMMESYIAVLTKGICQSEENGSFLSRDFDGRKAYLAGSIKDIVSQFGMETVILHTALMLKKRIVVYHPKIEAVQEFTRTLPALVWHRQDWTILHSYMHLHAEELEGLQMCTGYIAGFVELEVSNRPDLYDVFVNLADSEITIAPLAKEAMTMGKLHKEIGQLIVQSAEDPEKSDSQVIQDIALKTKEIFTHLAPFSEVSDDGGKVILNVEALKQQRFPPATENFLYHLAAAEQMLKV------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TCE6-1", "uniprot_id": "DEN10_HUMAN", "id": "Q8TCE6-1", "name": "DENN domain-containing protein 10", "aln": "--------------------MAAAEVADTQLMLGVGLIEKDTNGEVLWVWCYPSTTATLRNLLLRKCCLTDENKLLHPFVFGQYRRTWFYITTIEVPDSSILKKVTHFSIVLTAKDFNPEKYAAFTRILCRMYLKHGSPVKMMESYIAVLTKGICQSEENGSFLSKDFDARKAYLAGSIKDIVSQFGMETVILHTALMLKKRIVVYHPKIEAVQEFTRTLPALVWHRQDWTILHSYVHLNADELEALQMCTGYVAGFVDLEVSNRPDLYDVFVNLAESEITIAPLAKEAMAMGKLHKEMGQLIVQSAEDPEKSESHVIQDIALKTREIFTNLAPFSEVSADGEKRVLNLEALKQKRFPPATENFLYHLAAAEQMLKI------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NSW5-1", "uniprot_id": "DE10B_HUMAN", "id": "Q6NSW5-1", "name": "Putative DENN domain-containing protein 10 B", "aln": "--------------------MAAAELADTQLMLGVGLIEKDTNGEVLWVWCYPSTTATLRNLLLRKCCLTDENKLLHPFVFGQYRRTWFYITIIEVPDSSILKKVTHFSIVLTAKDFNPEKYAAFTRILCRMYLKHGSPVKMMESYIAVLTKGICQSEENGSFLSKDFDARKAYPAGSIKDIVSQFGMETVILHTALMLKKRIVVYHPKIEAVQEFTRTLPALVWHRQDWTILHSYVHLNADELEALQMCTGYVAGFVDLEVSNRPDLYDVFVNLAESEITIAPLAKEAMAMGKLHKEMGQLIVQSAEDPEKSESQVIQDIALKTREIFTNLAPFSEVSADGEKRVLNLEALKQKRFPPATENFLYHLAAAEQMLKI------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8E7G4-1", "uniprot_id": "DEN10_DANRE", "id": "A8E7G4-1", "name": "DENN domain-containing protein 10", "aln": "-------------------------MATPELMLSLGLIEKDVNADTLWVWCYPSIDADLREVMLRKCCLTLDNQVLHTFVFGQFCRTWYYITTVEVQEPTVLKKVTHFSIVVTAKDFNPEKYAAFSRVLCRTYMKHGSPVKMMEGYIAVLTKGICQSDENGSFLIKDYDVRKALLAGSLKDVVSQFGMETIILYTALMLKKRVVVYHPRIEALLEFTRALPCLVWHRKDWSILHPFVHLENDELENLKVCTGYVAGFVDPEVKDRSDLFDVFVNLPDSEITVSQNAKEAMSMGKLHKEIGNFIVQAAEDADRSDAQVIKDISVKTKEILSNLMSLADHADNS---KLTLECLKQGHYPPATENFLFHLAAAEQLLKI------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:***.:****** *.:.******** * **:::******* :*::**.*****: ***:*:* :** :.::**********:*************:*:*** *:*:********.************:****** :*:* *** ***:**:********:**:********:*****:***: ****:**.*****:**:***.::**. :*** *::****:****: **.:*.**:******.:*** :: *****:*******:*::***:***.::*:::**:**::**:**:::* .::: : . *.:*.*** ::********:*******:** ", "identical_positions": 229, "similar_positions": 90, "identity": "54.65%" }, { "cls_id": "homologset.agr.RGD:1308327", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z8W2-1", "uniprot_id": "D3Z8W2_RAT", "id": "D3Z8W2-1", "name": "Nucleic acid dioxygenase ALKBH1", "aln": "MGKMAAAVVSLTSLATEPKEDAFRKLFRFYRQSRRSTADLGAVIDFSEAHVAQSPKPGVPKVVRFPLNVSSVTEHDTSRAGLQPVSKWQAYGLEGYPGFIFIPNPFLPGCQWHWIKQCLKLYSQKPNVCNLDKHMTKEETQGLWEQSKEFLRSKDKTKRRPRSLLERLRWVTLGYHYNWDSKKYSADHYTPFPSDLAFLSEQVATACGFQGFRAEAGILNYYRLDSTLGIHVDRSELDHSKPLLSFSFGQSAIFLLGGLKRDEAPTAMFMHSGDIMVMSGFSRLLNHAVPRVLPHPDGECLPHCLETPLPAVLPS-----GSLLEPCSVEDWQVCATYLKTARVNMTVRQVLATGQDFPLEPMEEPKRDITADGLCHLHDQKSPVKRKRLNTND", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0CB42-1", "uniprot_id": "ALKB1_MOUSE", "id": "P0CB42-1", "name": "Nucleic acid dioxygenase ALKBH1", "aln": "MGKMAAAVASLATLAAEPREDAFRKLFRFYRQSRPGTADLGAVIDFSEAHLARSPKPGVPQVVRFPLNVSSVTERDAERVGLEPVSKWRAYGLEGYPGFIFIPNPFLPGCQRHWVKQCLKLYSQKPNVCNLDKHMTKEETQGLWEQSKEVLRSKEVTKRRPRSLLERLRWVTLGYHYNWDSKKYSADHYTPFPSDLAFLSEQVATACGFQGFQAEAGILNYYRLDSTLGIHVDRSELDHSKPLLSFSFGQSAIFLLGGLKRDEAPTAMFMHSGDIMVMSGFSRLLNHAVPRVLPHPDGECLPHCLETPLPAVLPS-----NSLVEPCSVEDWQVCATYLRTARVNMTVRQVLATGQDFPLEPVEETKRDIAADGLCHLHDPNSPVKRKRLNPNS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13686-1", "uniprot_id": "ALKB1_HUMAN", "id": "Q13686-1", "name": "Nucleic acid dioxygenase ALKBH1", "aln": "MGKMAAAVGSVATLATEPGEDAFRKLFRFYRQSRPGTADLEGVIDFSAAHAARGKGPGAQKVIKSQLNVSSVSEQNAYRAGLQPVSKWQAYGLKGYPGFIFIPNPFLPGYQWHWVKQCLKLYSQKPNVCNLDKHMSKEETQDLWEQSKEFLRYKEATKRRPRSLLEKLRWVTVGYHYNWDSKKYSADHYTPFPSDLGFLSEQVAAACGFEDFRAEAGILNYYRLDSTLGIHVDRSELDHSKPLLSFSFGQSAIFLLGGLQRDEAPTAMFMHSGDIMIMSGFSRLLNHAVPRVLPNPEGEGLPHCLEAPLPAVLPR-----DSMVEPCSMEDWQVCASYLKTARVNMTVRQVLATDQNFPLEPIEDEKRDISTEGFCHLDDQNSEVKRARINPDS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7KUZ2-1", "uniprot_id": "Q7KUZ2_DROME", "id": "Q7KUZ2-1", "name": "", "aln": "---------------------MFKLVFKQYK-CKSTSPDLTEVVKIDDCVVKGNDQEKSDNNIVQRLSISNVESLQTMPG-VKSPKDWRTYTLTNHPGIIVIRNPFSERGRRYWSARCLRDFPRTPNIVNLNERLFDESVRSDWWKQLNLCSDGVEFQR----IKSAMRWTTFGYHHNWDTKIYDEEMQSPFPEDLSSLCGLFAQALGYADFKPEAAIVNYYPVGSTLSGHTDHSEPNKSAPLFSFSFGQTAIFLIGGRSLEEKPTAIYLQSGDVMIMSGESRLCYHAVPRIIKTQASATLSLIIEDVDNADIKTRTIDKDLFHDVGNPQFWEPFSRYMDDSRININIRQVLNPGDVKL-----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: :*: *: .: :.** *:.:. . . : : *.:*.* . :: ::. ..*::* * .:**:*.* *** : :* :**: :.:.**: **:::: .*..:. * :. :. :* : . :**.*.***:***:* *. : :***.**. *. .* * *: .*:.**.*:*** :.***. *.*:** ::* **:******:****:** . :* ***::::***:*:*** *** *****:: . *. :* * : . : : . : *: : *: :*:*:.:**** ..: ", "identical_positions": 108, "similar_positions": 116, "identity": "27.41%" }, { "cls_id": "homologset.agr.RGD:1308329", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L144-1", "uniprot_id": "A0ABK0L144_RAT", "id": "A0ABK0L144-1", "name": "", "aln": "------------------------------------------------MPRPELPLPEGWEEARDFDGKVYYIDHRNRTTSWIDPRDRYTKPLTFADCISDELPLGWEEAYDPQVGDYFIDHNTKTTQIEDPRVQWRREQEHMLKDYLVVAQEALSAQKEIYQVKQQRLELAQQEYQQLHAVWEHKLGSQVSLVSGSSSSSKYDPEILKAEIATAKSRVNKLKREMVHLQHELQFKERGFQTLKKIDERMSDAQG-GYKLDEAQAVLRETKAIKKAITCGEKEKQDLIKSLAMLKDGFRTDRGSHSDLWSSSSSLESSSFPVPKQFLDVSSQTDISGSFSTSSSN--QLAEKVRLRLRYEEAKRRIANLKIQLAKLDSEAWPGVLDSERDRLILINEKEELLKEMRFISPRKWTQGEVEQLEMARRRLEKDLQAARDTQSKALTERLKLNSKRNQLVRELEEATRQVAALHSQLKSLSS-SMQSLSSGSSPGSLTSSRGSLAASSLDSSTS----------ASFTDLYYDPFEQLDSELPSKVELLFLEGATGFRPSGCITTIHEDEVAKTQKAEGGSRLQALRSLSGTPRSMTSLSPRSSLSSPSPPCSPLIADPLLAGDAFLTPLEFEDTELSPTLCELSLGTDGARERFRLEEPGPEGKPLGQAASVAPGCGLKVACVSAAVSDESVAGDSGVYEASMQRLGTSEAAAFDSDESEAVGVTQVQIALKYDEKSKQFAILVIQLSNLSALLLQ--QDQKVNIRVAILPCSESSTCLFRTRPLDSADSLVFNEAFWVSMSYPALHQKTLRVDVCTTDRSHTEECLGGAQISLAEVCRSGERSTRWYNLLSYKYLKKQGREPQPA----EAPGPDHVDAVSALLEQTAVELEKRQEGRSSSQTLEGSWTYEEEASENEAVAEEEER-----------EEEEGEEDVFAEKVSP----EAEECPALKVDRETNTDSVTPSPTVVRPKDRRVGAPSPGPFLRGNTIIRSKTFSP---GPQSQYVCRLNRSDSDSSTLSKKPP--FVRNSLERRSVRMK--RPSSVKSLRTERLIRTSLDLELDLQATRTWHSQLTQEISVLKELKEHLEQAKNHGEKELPQWLREDERFRLLLRMLEKR-VDRGEHKSELQADKMMRAAAKDVHRLRGQSCKE-PPEVQSFREKMAFFTRPRMNIPALSADDV----------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5SXA9-1", "uniprot_id": "KIBRA_MOUSE", "id": "Q5SXA9-1", "name": "Protein KIBRA", "aln": "------------------------------------------------MPRPELPLPEGWEEARDFDGKVYYIDHRNRTTSWIDPRDRYTKPLTFADCISDELPLGWEEAYDPQVGDYFIDHNTKTTQIEDPRVQWRREQEHMLKDYLVVAQEALSAQKEIYQVKQQRLELAQQEYQQLHAVWEHKLGSQVSLVSGSSSSSKYDPEILKAEIATAKSRVNKLKREMVHLQHELQFKERGFQTLKKIDERMSDAQG-GYKLDEAQAVLRETKAIKKAITCGEKEKQDLIKSLAMLKDGFRTDRGSHSDLWSSSSSLESSSFPMPKQFLDVSSQTDISGSFSTSSNN--QLAEKVRLRLRYEEAKRRIANLKIQLAKLDSEAWPGVLDSERDRLILINEKEELLKEMRFISPRKWTQGEVEQLEMARRRLEKDLQAARDTQSKALTERLKLNSKRNQLVRELEEATRQVATLHSQLKSLSS-SMQSLSSGSSPGSLTSSRGSLAASSLDSSTS----------ASFTDLYYDPFEQLDSELQSKVELLFLEGATGFRPSGCITTIHEDEVAKTQKAEGGSRLQALRSLSGTPRSMTSLSPRSSLSSPSPPCSPLITDPLLTGDAFLAPLEFEDTELSTTLCELNLGGSGTQERYRLEEPGPEGKPLGQAASVAPGCGLKVACVSAAVSDESVAGDSGVYEASAQRPGTSEAAAFDSDESEAVGATRVQIALKYDEKNKQFAILIIQLSHLSALSLQ--QDQKVNIRVAILPCSESSTCLFRTRPLDSANTLVFNEAFWVSISYPALHQKTLRVDVCTTDRSHTEECLGGAQISLAEVCRSGERSTRWYNLLSYKYLKKQCREPQPT----EAPGPDHVDAVSALLEQTAVELEKRQEGRSSSQTLEGSWTYEEEASENEAVAEEEE---------------EGEEDVFTEKVSP----EAEECPALKVDRETNTDSVAPSPTVVRPKDRRVGAPSTGPFLRGNTIIRSKTFSP---GPQSQYVCRLNRSDSDSSTLSKKPP--FVRNSLERRSVRMK--RPSSVKSLRTERLIRTSLDLELDLQATRTWHSQLTQEISVLKELKEHLEQAKNHGEKELPQWLREDERFRLLLRMLEKK-VDRGEHKSELQADKMMRAAAKDVHRLRGQSCKE-PPEVQSFREKMAFFTRPRMNIPALSADDV----------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IX03-1", "uniprot_id": "KIBRA_HUMAN", "id": "Q8IX03-1", "name": "Protein KIBRA", "aln": "------------------------------------------------MPRPELPLPEGWEEARDFDGKVYYIDHTNRTTSWIDPRDRYTKPLTFADCISDELPLGWEEAYDPQVGDYFIDHNTKTTQIEDPRVQWRREQEHMLKDYLVVAQEALSAQKEIYQVKQQRLELAQQEYQQLHAVWEHKLGSQVSLVSGSSSSSKYDPEILKAEIATAKSRVNKLKREMVHLQHELQFKERGFQTLKKIDKKMSDAQG-SYKLDEAQAVLRETKAIKKAITCGEKEKQDLIKSLAMLKDGFRTDRGSHSDLWSSSSSLESSSFPLPKQYLDVSSQTDISGSFGINSNN--QLAEKVRLRLRYEEAKRRIANLKIQLAKLDSEAWPGVLDSERDRLILINEKEELLKEMRFISPRKWTQGEVEQLEMARKRLEKDLQAARDTQSKALTERLKLNSKRNQLVRELEEATRQVATLHSQLKSLSS-SMQSLSSGSSPGSLTSSRGSLVASSLDSSTS----------ASFTDLYYDPFEQLDSELQSKVEFLLLEGATGFRPSGCITTIHEDEVAKTQKAEGGGRLQALRSLSGTPKSMTSLSPRSSLSSPSPPCSPLMADPLLAGDAFLNSLEFEDPELSATLCELSLG-NSAQERYRLEEPGTEGKQLGQAVNTAQGCGLKVACVSAAVSDESVAGDSGVYEASVQRLGASEAAAFDSDESEAVGATRIQIALKYDEKNKQFAILIIQLSNLSALLQQ--QDQKVNIRVAVLPCSESTTCLFRTRPLDASDTLVFNEVFWVSMSYPALHQKTLRVDVCTTDRSHLEECLGGAQISLAEVCRSGERSTRWYNLLSYKYLKKQSRELKPVGVMAPASGPASTDAVSALLEQTAVELEKRQEGRSSTQTLEDSWRYEETS-ENEAVAEEEEEE---------VEEEEGEEDVFTEKASP----DMDGYPALKVDKETNTETPAPSPTVVRPKDRRVGTPSQGPFLRGSTIIRSKTFSP---GPQSQYVCRLNRSDSDSSTLSKKPP--FVRNSLERRSVRMK--RPSSVKSLRSERLIRTSLDLELDLQATRTWHSQLTQEISVLKELKEQLEQAKSHGEKELPQWLREDERFRLLLRMLEKRQMDRAEHKGELQTDKMMRAAAKDVHRLRGQSCKE-PPEVQSFREKMAFFTRPRMNIPALSADDV----------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VFG8-1", "uniprot_id": "KIBRA_DROME", "id": "Q9VFG8-1", "name": "Protein kibra", "aln": "MPNLQQTASQSQHHLHPHHLRPQQQQQQHHHHHQQQQQQQHTHHQQQQQHHSDFPLPDGWDIAKDFDGKTYYIDHINKKTTWLDPRDCYTKPQTFEDCVGDELPMGWEESYDPNIGPYYINHLAQSTQLEDPRQEWKTVQEQMLSDYLSAAQDQLENKREMFDVKQQRLLWAQEEYNHLKLAAS-----RSSLCSSSSSMSRHDPELLRADLMLARERVHQLKQELTHITNDISYTERGMNTLYSVGEKINARENGCYDIAEVHAIREEMLKVHKSLVSGEKVREELMRSLVQIKN----------ELGRQQISEENSDLASPFDRVCVASQTDLCGSSGENLNGGARFAEMAKTKWQYAEWRKHIKKLQQQLADHVERIEPGQLESDKDRILLIQEKEKLLNDLNSISLKSRSEEEKRVIHQTRHKLEEDLKEAYEANNTCVANRLRFHEEKQLLLDKLQEALKSTKLLEERLKSFSSESTFSISSGSSLGSLSTASSKSALSFTDIYIDPFAVDSPIDVVDLRRRSQRLFQQHQQQRLHPVHPVLQQQQSAEVTLSPRSSLSMETPPASPMKYNAGADQTPQALKEEPTYANALPAPPAYTAPPPVPISGVRARPYDLDSTVLDCMMLEAKLQKLNMGTPLNLAVAPLSPISEKPSLLDLPQEMLSRSSSTS--NTRSVSAAVSNESVAGDSGVFEASRAHLPRKE-------------LAQVQIGLKYLKQEGVLVVSLERANNLLALWTASADNSQVYLRAALLPNSLTS---IRTKALGDFQKPVFNDTFAVPITLDKLLTKSLQVTVVTMTG-QKEEIIGTVQISMAEFN-PEDSTLKWYNVLSSKFIPSFESLDIPS--TSAAAAAAAVAASNAPNPGNNREESSDESTITSSQTSTLTRNQAPCMELQEQMAAELLGLGPLNEPECSDDDDDDEEEELDDKQLVSDVGLMNSSSMLHAYLQNMKQEFADKETNTDRAYLPEKSRGQSQLMDDRPVKRSQTFTPSEAFSKNRYNCRLNRSDSDSAMHCGVAPHTFQRGAAERRSLRFHSKAPKSVTKLHHTHIPRTSLDLELDLQAQHSKLYFLNDQIAKLQNLKEVLQKACENKDPLVAAWAIENEEFQRLVAR-----ADPAKCPEERQLQKLLMKTAKEIHKLRKTKVPKGCPDLVSFKEKITFFTRKGLSVPELPSEFTLPEANPIEEEEEEEDENEFYNSAETAIAINTALVASSNRNKNLSEHPHRATSGAVPKIPAPVVTPAATPAATPAATPAATSAATPAATPVVSPAAQPDAKPADAPIPVASNDAEQQRFDYVVDRNYGVEV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.::***:**: *:*****.***** *:.*:*:**** **** ** **:.****:****:***::* *:*:* :::**:**** :*: **:**.*** .**: *. ::*:::****** **:**::*: . . : ** *.*** *::***:*:*:: *:.**::**:*:.*: :::.:.***::** .:.:::. :. *.: *.:*: .* ::*::..*** :::*::**. :*: :* .. * *.*.:. * : : *:****:.** . . .. ::** .: : :* * :::* :*: ***. .. ** *:*::**::**:***:**:::. ** :. :: * . :. :*::**:**: * :::...:::**:::.::: *: :*:** :.. *..:***:** * *:***** ***::: .. . * * . ..: *:* :.: *. :: : :. . . ::: : . : ... *: ::*. * .:*.. .: ::*.* . : *: : : :.:*. *. : *:*. . : . :. .******:*********:*** : .* :::**.*** ::. :.: : : .:* ** ::.:* :*.*:** * :: :**:.*. :. ***:.* *.:: * *:*:* * * : ** :* .***:**. . : : :***:** *:: . * *... . * .* . * .. :. :*:** : :* :* * :.**: : :* : . *:. :. .: : . * . : . . :: . .: **:**:* .:.:* **********: . .* * *.: ****:*:: *.**..*: :: ************ :: *.::*: *::*** *::* .: : :. * *:*.*: *: * .: * * :*:: :**::*:** . : *:: **:**::**** :.:* *.:: . ", "identical_positions": 342, "similar_positions": 392, "identity": "25.71%" }, { "cls_id": "homologset.agr.RGD:1308330", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4A3L3-1", "uniprot_id": "D4A3L3_RAT", "id": "D4A3L3-1", "name": "Multiple epidermal growth factor-like domains protein 9", "aln": "MNGGAERAMRSLPSLGGLALFCCAAAAAAS----AASAGNVTGGGGAEGQVVASPSPGLREQTSSPFSKAAAPTAQAPRTGPPRTTVHRTGAATPSAGSPETIP-VRTSAQPAATLFPV-VDLSSATPSEDGHTPTTEPLPSRPAPTTLASTAGQAPTTSVVTTAQASSTPGTPTAESPDRGRNSSRVPPTAPVTEAPTPPPPEYMCNCSEVGSLDVKRCNQTTGQCDCHVGYQGLHCDTCKEGFYLNHTVGLCLPCHCSPRGAVSILCNSSGNCQCKLGVTGSMCDQCQDGHYGFGKTGCLPCQCNNRSDSCDVLTGACLNCQENTKGEHCEECKEGFYQSPD--AARECLRCPCSAVTSTGNCTIEFGALEPTCDQCKDGYTGQNCNTCENGYYHSDSICLQCECHGHVDPIKTPKICKPESGECINCLHNTTGLWCEKCLEGYVRDLQRNCIKQEVIVPTPEGSTILVSNASLTTSVPTPVINSTFAPTTLQTIFSVSSSENSTS-ALADVSWTQFNIIILTVIIIVVVLLMGFVGAVYMYREYQNRKLNAPFWTIELKEDNISFSSYHDSIPNADVSGLLEDDANEVAPNGQLTLTTPIHNYKA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BH27-1", "uniprot_id": "MEGF9_MOUSE", "id": "Q8BH27-1", "name": "Multiple epidermal growth factor-like domains protein 9", "aln": "MNGGAERAMRSLPSLGGLALLCCAAAAAAS----TASAGNVTGGGGAEGQVVPSPSPGLRDQASSPFPKTAAPTAQAPRTGPPRTTVRKTGATTPSAGSPEIIPPLRTSAQPAATPFPA-LDLSPATPSEDGHTPTTESPPSRPAPTTLASTVGQPPTTSVVTTAQASSTPGTPTAESPDRSSNSSGVPPTAPVTEAPTSPPPEHMCNCSEVGSLDVKRCNQTTGQCDCHVGYQGLHCDTCKEGFYLNHTVGLCLPCHCSPHGAVSILCNSSGNCQCKVGVTGSMCDKCQDGHYGFGKTGCLPCQCNNRSDSCDVHTGACLNCQENSKGEHCEECKEGFYPSPD--AAKQCHRCPCSAVTSTGNCTIESGELEPTCDQCKDGYTGQNCNKCENGYYNSDSICTQCECHGHVDPIKTPKICKPESGECINCLHNTTGFWCEKCLEGYVRDLQRNCIKQEVIVPTPEGSTILVSNASLTTSVPTPVINSTFAPTTLQTIFAVSSSENSTS-ALADVSWTQFNIIILTVIIIVVVLLMGFVGAVYMYREYQNRKLNAPFWTIELKEDNISFSSYHDSIPNADVSGLLEDDANEVAPNGQLTLTTPIHNYKA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H1U4-1", "uniprot_id": "MEGF9_HUMAN", "id": "Q9H1U4-1", "name": "Multiple epidermal growth factor-like domains protein 9", "aln": "MNGGAERAMRSLPSLGGLALLCCAAAAAAAAVASAASAGNVTGGGGAAGQVDASPGPGLRGEPSHPFPRATAPTAQAPRTGPPRATVHRPLAATSPAQSPETTP-LWATAGPSSTTFQAPLGPSPTTPPAAERTSTTSQAPTRPAPTTLSTTTGPAPTTPVATTVPAPTTPRTPTPDLP--SSSNSSVLPTPPATEAPSSPPPEYVCNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCKEGFYLNYTSGLCQPCDCSPHGALSIPCNSSGKCQCKVGVIGSICDRCQDGYYGFSKNGCLPCQCNNRSASCDALTGACLNCQENSKGNHCEECKEGFYQSPD--ATKECLRCPCSAVTSTGSCSIKSSELEPECDQCKDGYIGPNCNKCENGYYNFDSICRKCQCHGHVDPVKTPKICKPESGECINCLHNTTGFWCENCLEGYVHDLEGNCIKKEVILPTPEGSTILVSNASLTTSVPTPVINSTFTPTTLQTIFSVSTSENSTS-ALADVSWTQFNIIILTVIIIVVVLLMGFVGAVYMYREYQNRKLNAPFWTIELKEDNISFSSYHDSIPNADVSGLLEDDGNEVAPNGQLTLTTPIHNYKA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PS41-1", "uniprot_id": "A0A8M1PS41_DANRE", "id": "A0A8M1PS41-1", "name": "", "aln": "----MTCMRYTMLLFSVWELLLFGYTAGLSASDERRLPRAVLDETLEATTIPNHLQEDDRDSRFSPFTPAMTISNRDFRTTRNTNQVQSDWLTTTTTTT--------------------------TTPITTAELMTKTMNPTSEGSKVKENSTLSTTLNTTAKPTSSSPINDTKNTTPPALDTSNSTRTVKSTSNPPVVTTEKGLQCNCSTEGSVDPYTCDSVTSQCVCIIGYTGQRCDECEDEYFTNGTNG-CQPCDCHSYGAVSGLCNSSGMCNCKMGVHGDKCDDCLPGFMYFSSTGCQTCQCNNHSSYCHPQSGICVNCQGNTEGRSCEKCKYNFYRRPGSPVTEPCIPCPCSSVTSTGSCKLDSR-GQPYCVQCKPEYQGPNCEQCSDGFYNADSICLPCNCSGNGDPRLSPRICHPDTGYCLSCINNSTGPHCERCADGFTGDPLARNCTPTVVHTTPSSTTGWFLYTTMTSS-PNATTQFTSTTALLSSLASSTPNTTTTTTTVTPLPWNQFNIIILAVIIIVVIALLAVVGGVYTYREYQNRKLNAPFWTIELKEDNISFSSYHDSIPNADISGLLEDEVSDMG-NGQLALTGPGSLYKV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8N7TEX5-1", "uniprot_id": "A0A8N7TEX5_DANRE", "id": "A0A8N7TEX5-1", "name": "", "aln": "-MWWLALMMFTSPAFPFIVFVCMGLTEAAHSYD--ALPLVIRKSRAVAEEHP----ETNADG-FSGHRLGIVALTPAPTITSARNPIN----VAAPAAT--------------------------IKPATTDPATPSPYNPSYMAAFARR------KLSSLETQMKVALMSDNR------ADRSAAVPDFSTTSD-----NSQELVCNCSGEGVSDPDECDRKTGQCDCMPGYTGLQCEECEEDHFTNGTIG-CLPCACDSFGAHGTSCDSSGMCTCKMGVYGPKCDDCHPGFFHFSSTGCQPCQCNNHSTYCHPQSGICLDCQDNTQGHNCEECLPSFYRRGGEGSADVCLPCPCSSETSSGICHLDSS-GRPVCAECKPGFTGPTCDSCTDGLFKSAGTCIPCDCNGNADPRSVPQICHPETGHCHRCVNHTTGAHCEICARGYTGDARRHNCTLRAVKVLPTTSVSSTPSSRLLTS-SSPTTN--PSLPTLQSGTGDSAGHNSTASALTVVSWTQFNIIILAVIIVVVVLLMGFVGGVYTYREYRNRKLNAPFWTIELKEDNISFSSYHDSIPHADPNGLLEEEPCVVAANGQLALATAANMYKA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :. . : . . : . . :. .:..: : .* .. *: .. . .. . . . . . : ... **** * : *: *.** * ** * :*: *:: .: * * * * ** * . ** . *:*** * **:** * ** * *. *...** .*****:* *. :* *::** *::*. **:* .** . : * ****: **:* * :. .* * :** : * .*: * :* :: . * *:* *: ** *:**:*::* * *::::** ** * *:. * . . .: * :. : : :* .... : : . *.: . :.. .:*: ::: :.*.*******:***:**: *:..**.** ****:****************************:** .****:: :. ****:*: . **.", "identical_positions": 165, "similar_positions": 141, "identity": "27.14%" }, { "cls_id": "homologset.agr.RGD:1308332", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "B2RZ78-1", "uniprot_id": "VPS29_RAT", "id": "B2RZ78-1", "name": "Vacuolar protein sorting-associated protein 29", "aln": "MLVLVLGDLHIPHRCNSLPAKFKKLL-VPGKIQHILCTGNLCTKESYDYLK---TLAGDVHIVRGDFDESLNYPEQK-----------------VVTVGQFKIGLIHGHQVIPWGDMASLALLQRQFDVDILISGHTHKFEAFEHENKFYINPGSATGAYN-----------------------------------------------------------ALETNIIP----------------------SFVLMDIQASTVVTYVYQLIGDDVKVERIEYKKS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QZ88-1", "uniprot_id": "VPS29_MOUSE", "id": "Q9QZ88-1", "name": "Vacuolar protein sorting-associated protein 29", "aln": "MLVLVLGDLHIPHRCNSLPAKFKKLL-VPGKIQHILCTGNLCTKESYDYLK---TLAGDVHIVRGDFDENLNYPEQK-----------------VVTVGQFKIGLIHGHQVIPWGDMASLALLQRQFDVDILISGHTHKFEAFEHENKFYINPGSATGAYN-----------------------------------------------------------ALETNIIP----------------------SFVLMDIQASTVVTYVYQLIGDDVKVERIEYKKS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UBQ0-1", "uniprot_id": "VPS29_HUMAN", "id": "Q9UBQ0-1", "name": "Vacuolar protein sorting-associated protein 29", "aln": "MLVLVLGDLHIPHRCNSLPAKFKKLL-VPGKIQHILCTGNLCTKESYDYLK---TLAGDVHIVRGDFDENLNYPEQK-----------------VVTVGQFKIGLIHGHQVIPWGDMASLALLQRQFDVDILISGHTHKFEAFEHENKFYINPGSATGAYN-----------------------------------------------------------ALETNIIP----------------------SFVLMDIQASTVVTYVYQLIGDDVKVERIEYKKP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZV68-1", "uniprot_id": "VPS29_DANRE", "id": "Q7ZV68-1", "name": "Vacuolar protein sorting-associated protein 29", "aln": "MLVLVLGDLHIPHRCNTLPAKFKKLL-VPGKIQHILCTGNLCTKESYDYLK---TLAGDVHIVRGDFDENLNYPEQK-----------------VVTVGQFKIGLIHGHQVIPWGDMASLALLQRQLDVDILISGHTHKFEAFENENKFYINPGSATGAYS-----------------------------------------------------------ALESNITP----------------------SFVLMDIQASTVVTYVYQLIGDDVKVERIEYKKS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VPX5-1", "uniprot_id": "Q9VPX5_DROME", "id": "Q9VPX5-1", "name": "Vacuolar protein sorting-associated protein 29", "aln": "MLVLVLGDLHIPHRCSSLPAKFKKLL-VPGRIHHILATGNICTKESYDYLK---SLANDVHIVRGDFDENLTYPEQK-----------------VVTVGQFRIGLCHGHQVVPRGDPEALALIQRQLDVDILITGHTYKFEAYEHGNKFYINPGSATGAFN-----------------------------------------------------------PLDTNVVP----------------------SFVLMDIQSTTVVTYVYQLIGDEVKVERIEYKKI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38759-1", "uniprot_id": "VPS29_YEAST", "id": "P38759-1", "name": "Vacuolar protein sorting-associated protein 29", "aln": "MLLLALSDAHIPDRATDLPVKFKKLLSVPDKISQVALLGN--STKSYDFLKFVNQISNNITIVRGEFDNGHLPSTKKDKASDNSRPMEEIPMNSIIRQGALKIGCCSGYTVVPKNDPLSLLALARQLDVDILLWGGTHNVEAYTLEGKFFVNPGSCTGAFNTDWPIVFDVEDSDEAVTSEVDKPTKENQSEDDDAKGGSTGKEQPGSYTPKEGTAGERENENESNVKPENQFKEDEVDMSDSDINGSNSPSFCLLDIQGNTCTLYIYLYVNGEVKVDKVVYEKE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:*.*.* ***.*.. **.****** **.:* :: ** :.:***:** ::.:: ****:**:. . :* :: * ::** *: *:* .* :* : **:*****: * *::.**: .**::****.***:. ::*: * ** *:***..* . *:* :..:***::: *:* ", "identical_positions": 78, "similar_positions": 62, "identity": "27.46%" }, { "cls_id": "homologset.agr.RGD:1308333", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZRT2-1", "uniprot_id": "D3ZRT2_RAT", "id": "D3ZRT2-1", "name": "Enolase 4", "aln": "MGEEGGGRSGGISR---DLLKLKQQAMAYYQENDVPRKLEELLNSTFYLQPADVYGHL-ANYFSKLAKPPSICKIVGKTILDGLGLPTLQVEISCTIQNFPKYICSVAIPTHSEVVENALP--EMVDADEAERQQAVSKAVRWINQFITEELWGLIPSNQAEVDRRLRIFFEHKVQADKDRKELERSQE-EPVPMTLPVILPPPPPPP----SKKKGQKAGRRDTLLEKPIFPPEPPEPVLHGSMAIGAVSLAVAKTSATLAGTPLYLTLALLKHDQEQPSTFSMPLLMGSVLSCGKSSPGKLHLMKEVMCIPSPGLTTKQGIELLLEIQKQVNRAMETLPPPKPETKKGHNGGKRSQPPITGRASHLGCLTINYDTIEQPLLLIQGICSNLGLELGVNFHLAINCAGHELMDYSKGKYEVMVGTYKS-------AAEMVELYVDLINKYPSIIALIDPFRKEDSEQWDSLYAAVASRCYLIAGAASRSVSRLLEDRNISLLKYHGLIIKHTNQTTMSDLVEITHLINGKKHLAVFGSTDSESSDDSLVDLAVGLGARFIKLGGLSRGERMTKYNRLLAIEEELIQSGAWGFSEEHNFSFFQEDAT----TTTAEETLEPLDSIFPTEVIEESAKT-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C042-1", "uniprot_id": "ENO4_MOUSE", "id": "Q8C042-1", "name": "Enolase 4", "aln": "MGDEDGGRRGGITR---DLQKLKQQAMAYYQENDVPRKLEDLLNSTFYLQPADVYGHLKANYFSKLAKPPSICKIVGKTILDGLGLPTLQVEISCTIQNFPKYICAVAIPTHFEVVENALP--EALDAEDSERAQAVNTAVQWINQSITEELWGLVPSNQAEVDHRLRTFFEHKVQEDKERKELEKSQE-ELVPAPPPVTLPPPPPPPPPPPSKKKGQKAGRRDTLLEKPVSPPEPPEPVLHGSMAIGAVSLAVAKASATLASDPLYLTLASLKHDQEQPSTFSMPLLMGSVLSCGKSSPGKLHLMKEVICIPSPGLTAKQSVELLLEIQKQVNRAMETLPPPKQETKKGHNGSKRAQPPITGKVSHLGCLTINYDAIEQPLLLLQGICSNLGLELGVNFHLAINCAGHELMDYSKGKYEVMVGTHKS-------AAEMVELYVDLINKYPSIIALIDPFRKEDAEQWDSLYAALASRCYLIAGAASGSVSKLLECRNISTLKSHGLIIKHTNQTTMSDLVEITHLINGKKLLAVFGSTDSESSDDSLVDLAVGFGARFIKLGGLSRGERMTKYNRLLAIEEELIQRGVWGFSEEHNFSFFQEDAT----ATMAEETLGLLDSIFPTEVIEESAKT-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NNW6-3", "uniprot_id": "ENO4_HUMAN", "id": "A6NNW6-3", "name": "Enolase 4", "aln": "MEEEGGGRSCGTTR---ELQKLKQQAMEYYRENDVPRRLEELLNSTFYLQPADVYGHL-ANCFSKLAKPPTICKIVGKDVLDGLGLPTLQVDIFCTIQNFPKNVCSVVISTHFEVHENALP--ELAKAEEAERASAVSTAVQWVNSTITHELQGMAPSDQAEVDHLLRIFFASKVQEDKGRKELEKSLEYSTVPTPLPPVPPPPPPPPP---TKKKGQKPGRKDTITEKPIAPAEPVEPVLSGSMAIGAVSLAVAKACAMLLNKPLYLNIALLKHNQEQPTTLSMPLLMVSLVSCGKSSSGKLNLMKEVICIPHPELTTKQGVEMLMEMQKHINKIIEMPSPPKAETKKGHDGSKRGQQQITGKMSHLGCLTINCDSIEQPLLLIQEICANLGLELGTNLHLAINCAGHELMDYNKGKYEVIMGTYKN-------AAEMVDLYVDLINKYPSIIALIDPFRKEDSEQWDSIYHALGSRCYIIAGTASKSISKLLEQGNISIPKSNGLIIKHTNQTTMSDLVEITNLIDSKKHITVFGSTEGESSDDSLVDLAVGLGVRFIKLGGLSRGERVTKYNRLLTIEEELVQNGTLGFKEEHTFFYFNEEAEKAAEALEAAAAREPLVPTFPTQGVEESAETGASSG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08BC6-1", "uniprot_id": "ENO4_DANRE", "id": "Q08BC6-1", "name": "Enolase 4", "aln": "MSYKGFPSHSKVSKEDQEFYDLKNKAAEYYRSNGVPQKIESVLNEMFWQKPDDIYGYL-ANYFSGLSYTPVISKITGKEVFDGRGLTAVQAEVHCIIRNEEKMVCGAVMDGSFDGLPDGVESGEMLSNGD-LQHLSITMALKWIRENFSPVLRGFNPTDQTNVDKILSDFAMARYLEHKDSLIREKEEELRNEAMSEAPPQATPTSAPA---KDKKGNDKGKKGNITENPLPPAEPPVPRLPGATAVGAVSLAVAKTAAELLGTPLYRHITAVRDPQAQK-EMQLPVPIITIMSCGKNSAGKLNLLEEIILMPSSSLRVREVIGMGLDLQCEMRRILN--------------GSTYKALPVG--VSDEGALQVGFDRPEQALDLLAEACANLALPLGSDLHLAVNCAAHSLMDYSRGKYEVMSGCHKS-------PDELVDIYEGLINKYPAIRSLIDPFRKEDVGQWERLASVIGQSCCLLADAASNLCPRWREAKPLPP-GATKAIIRHHSDMTISDLIQS--IAEHKETILAAG-----SGDASMVDLAVGSGVSFLKLGGLRGAKRMDKYNRLMAIEEE--QEGIAGAGEINQPVSFESESG--------------------WNSLTVSAK------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P15007-1", "uniprot_id": "ENO_DROME", "id": "P15007-1", "name": "Enolase", "aln": "MSWTASVFLRTSTTS-MKFLRLR-WPLPRIPQNKSANVAPRFRSKSAVSQLSSGFKFVQIRKSTCDSNEMTIKAIKARQIYDSRGNPTVEVDLTTELGLFRAAVPSGASTGVHEALELRDN------DKANYHGKSVLKAVGHVNDTLGPELIKAN---LDVVDQASIDNFMIKLDGTENKSK----------------------------------------------------------FGANAILGVSLAVAKAGAAKKGVPLYKHIADLAGN----KEIILPVPAFNVINGG-SHAGNKLAMQEFMILPTGATSFTEAMKMGSEVYHHLKNVIK-----------------AKFGLDATAVGDEGGFAPNIQSNKEALNLISDAIAKAGYTGKIEIGMDVAAS----EFYKDGQYDLDFKNEKSDKSQWLPADKLANLYQEFIKDFP-IVSIEDPFDQD---HWEAWSNLTGCTDIQIVGDDLTVTNPKRIATAVEKKACNCLLLKVNQIGTVTESIAAHLLAKKNGWGTMVSHRSGETEDSFIGDLVVGLSTGQIKTGAPCRSERLAKYNQILRIEEEIGAGVKFAGKSFRKPQ------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : .: *: . .* .. . .. : . : .: . : : * * .: : *. * .:::.:: : : . . : : :: *: :.. : * **: : : *: *: .*******: * . *** :: : : :*: .::. * . .*: ::*.: :* : : : :: .:.. :: .. * : . : ::.* *: :: . :: : : .: *. *:*:: *. . ::.::* :*:.:* * :: *** :: :*: . :.. : ::: . *::: : : . : . : * : **.** .. :* *. .:*: ***::: **** . . . ", "identical_positions": 60, "similar_positions": 152, "identity": "9.36%" }, { "cls_id": "homologset.agr.RGD:1308334", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4A9G5-1", "uniprot_id": "D4A9G5_RAT", "id": "D4A9G5-1", "name": "", "aln": "MMMYIRQRKETKPVEVSEDFPSP-------KEDVKLEKKLPSGCASG-----------RFWKILSSAVGGTVALCIGLLTSVYLATLHENDLWFSNIKEVEREISFRTECGLYYSYYKQMLQAPTLLQGFHGLIYDNKTESMRTINLLQRMNIYQEVFLSVLYRVLP--IQKYLEPVYFYIYTLFGLQAVYVTALYITSWLLSGTWLSGLLAALWYVTNRIDTTRVEFTIPLRENWALPFFAIQIAAITYFLRPNLQPLSERLTLLAIFVS---TFLFSLTWQFNQFMMLLQALVLFILDSLDMLPAVKATWLYGIQISCLLLVCMLQFFNSMILGSLLISFNLSVLIVRKLQKNLKTG--------TFLIRIWKLLLHLLLVFCLTLFLNNIIKKILNLKS-----------DEHIFKFLKAKFGFGATRDFDANLYLCEEAFGLLPLNTFQRLSETLLFYAYMFVLLVTVVTASVVAFHNLSDSTSLQPVDQTRKRVVDLKPEAAYNLIHTILFGVLALSTMRMKYLWTSHMCVFASFG----LCSSEIWELILRLVHLCNPKRIWVMRYSVPVLTLLCLCCKSWPGMMDELSELKEFYDPDTVELMNWINSNTPR------KAVFAGSMQLLAGVKLCTGRTLTNHPHYED--KSLRERTQAVYQIYAKR---SPE---------EVHALLRSFGTDFVIL----------------------EDSICYERRHHRG-----------CRLRDLLDVANGHEMDGPGESDPDLRP---------------------------ADHPRFCEEIKRNLPSYAAHFT------RVFQNKTFHVYKLSRNK------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q71B07-1", "uniprot_id": "D19L3_MOUSE", "id": "Q71B07-1", "name": "Protein C-mannosyl-transferase DPY19L3", "aln": "-MMYIRQRKETKPIEVSEDFPSP-------KEDVKLEKKLPSGCASG-----------RFWKILSSAVGGTVALCIGLLTSVYLATLHENDLWFSNIKEVEREISFRTECGLYYSYYKQMLQAPTLLQGFHGLIYDNKTESMRTINLLQRMNIYQEVFLSVLYRVLP--IQKYLEPVYFYIYTLFGLQAVYVTALYITSWLLSGTWLSGLLAALWYVTNRIDTTRVEFTIPLRENWALPFFAIQIAAITYFLRPNLQPLSERLTLLAIFVS---TFLFSLTWQFNQFMMLLQALVLFILDSLDMLPAMKATWLYGIQISCLLLVCTLQFFNSMILGSLLISFNLSVLIVRKLQKNLKTG--------SFLTRIWKLLLHLLLVFCLTLFLNNIIKKVLNLKS-----------DEHIFKFLKAKFGFGATRDFDANLYLCEEAFGLLPLNTFQRLSETLLFYAYMFVLVVTVVTASVVAFHNLSDSTSLKSMDQTRKRAVDLKPEAAYNLIHTILFGVLALSTMRMKYLWTSHMCVFASFG----LCSSEVWELLLRLVHLCNPKRIWVLRYLVPVLTLLYLCYKSWPGVMDELSELKEFYDPDTVELMTWINSNTPR------KAVFAGSMQLLAGVKLCTGRTLTNHPHYED--KSLRERTQAVYQIYAKR---SPE---------EVHALLRSFGTDFVIL----------------------EDSICYERRHHRG-----------CRLRDLLDVANGHEMDGPGESDPDLRP---------------------------ADHPRFCEEIKRNLPSYAAHFT------RVFQNKTFHVYKLSRNK------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZPD9-1", "uniprot_id": "D19L3_HUMAN", "id": "Q6ZPD9-1", "name": "Protein C-mannosyl-transferase DPY19L3", "aln": "-MMSIRQRREIRATEVSEDFPAQ-------EENVKLENKLPSGCTSR-----------RLWKILSLTIGGTIALCIGLLTSVYLATLHENDLWFSNIKEVEREISFRTECGLYYSYYKQMLQAPTLVQGFHGLIYDNKTESMKTINLLQRMNIYQEVFLSILYRVLP--IQKYLEPVYFYIYTLFGLQAIYVTALYITSWLLSGTWLSGLLAAFWYVTNRIDTTRVEFTIPLRENWALPFFAIQIAAITYFLRPNLQPLSERLTLLAIFIS---TFLFSLTWQFNQFMMLMQALVLFTLDSLDMLPAVKATWLYGIQITSLLLVCILQFFNSMILGSLLISFNLSVFIARKLQKNLKTG--------SFLNRLGKLLLHLFMVLCLTLFLNNIIKKILNLKS-----------DEHIFKFLKAKFGLGATRDFDANLYLCEEAFGLLPFNTFGRLSDTLLFYAYIFVLSITVIVAFVVAFHNLSDSTNQQSVGKMEKGTVDLKPETAYNLIHTILFGFLALSTMRMKYLWTSHMCVFASFG----LCSPEIWELLLKSVHLYNPKRICIMRYSVPILILLYLCYKFWPGMMDELSELREFYDPDTVELMNWINSNTPR------KAVFAGSMQLLAGVKLCTGRTLTNHPHYED--SSLRERTRAVYQIYAKR---APE---------EVHALLRSFGTDYVIL----------------------EDSICYERRHRRG-----------CRLRDLLDIANGHMMDGPGENDPDLKP---------------------------ADHPRFCEEIKRNLPPYVAYFT------RVFQNKTFHVYKLSRNK------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58G0T2-1", "uniprot_id": "A0AC58G0T2_DANRE", "id": "A0AC58G0T2-1", "name": "", "aln": "-MRACRSRKSNSDDNSGSALHRPPLVNFGTKDNSRVYKSGQRGIEECLKLSWIHILGPNCWPAVVIAAGLLLAGVIGLFHAWCVYSIHENLLWFSHLKEVEREISFRTECGLYYSYYKQMLKAPTIQQGLYELTHDNTTESKRTINILQRMNIYQEVFLSILYRILP--IQTYLEPIYFYIYTVFALQTVYVIALFITSWLLSDSWLAGALSGVWYILNRVDTTRVEFTISLRENWSIPFFALQVAAITCYLRPKLKPIHQRVVLWLVFVS---TFCFCLTWQFNQFVLLVQALIIYTLDCLDFLTAEQVVSLYLMQVSSLLLVWLLQFCNSMILGSLVLSFIVSALFIKHFQTGLKMG--------GFVIRVGKLALHTLLVLALTFTINYSAKKVLQLKS-----------DEHIFKFIKAKFGFGATRDFDASLYLCEEAFGLLPLDTFERLAGTVLLYPYLCTLSVLFILLLLVALSNLSLNGLGQASGEKEDRTFKMRPDVAYNLMHTVFFGLLAFSTMRMKYLWTGHMCTIAAFG----VCGKEVWALYLRVLHCNTKTAMRLIRYSVPIVILAFLYYKFWPRLMEEISELREFYDPDTVELMEWISMETSPPTTGLLKCLCVATRIHRRALSYSTIGMKIEISKTKT--ETISALTDGVICYLNKKEGSTPEFEEGVSYILQKHTLSNKFGQMYLFVGPGSLKFKTTPHNFSEAAQTSAKEALCPPSPEMTGGEPDIFSRGGHISLRGQITEFHGVRMTRARVPIVDLKIKCLEGTFSVSLWREAALTELFVGDEVLITHLRPCVQETGTGKFHSSNYTTVEIAEGQMQETVVEVIGVSNVNHTCHFLGSDSQVYVVPQIVFAGNPDDLIARLPLHLSLKHVNRRVFQISEVSE--------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VWR8-1", "uniprot_id": "DPY19_DROME", "id": "Q9VWR8-1", "name": "C-mannosyltransferase dpy-19 homolog", "aln": "-------------------MREP--------------------------------------NLYVILSHALIGCGFFFLYVQHVRVIFETRTNIQQLNQLEREALLRREDALYYAFYKQLAEGPDFWHGYEQLKNVTDIEYPHSVNVLQRFYVLPELVTAYFFHVVRSGFNPMVQPMQFYLEFVWLMGGVTLLVLYLYGTLLSENIFGGIYGVISYLMFHSFVAKIYERPLARENFAFPFIFLQMFYLCICIGRIIHRQRHTSRMFMIFAMSLFTACALLSWQFSTFIFTTQILIMMTSWNASALPTALVNAFVLDYSLSHLLGHALAFVMSHGNSQLLLTWQLSISLFLFLITMVRQLRHVRSRRLGHAQDLLNGDLFSLKFLMLTLLLASSVQTTLIELFNRAGVVSVTEGDQQHFFDICAHWALQVNVGFVAHLSACNPQYARVAWSELWQLVKTMIVKPYCMYGVVMLAMFFRRWRKSGAPVSALTEEQRERARKYVLEDFIEEHFVSMSDMSSKETEKQLYKCFRLLKSCDYDYERYKRAQASLRKEQPPARDDFMQDIKRLRAQINRNSVKQRKERAQETKEAATDGASTPTEEEDKDPEAESESKKKNQEPGSGETETESAADPTETPPSRSADNEEEEEEHSATAAGCGSNSSGHRQRKRSSSRRSSVVPTANAQILNMHYVYSFLQMLVFTLIGLAVRKLFFLSFTQG------CVIAPTVCSKLWYHRQR-----NIFWSVSLAVFLLSMFDPGMVNIREEYFPTRYSKSGDDLDSMLEWIKLNTERDAVFAGPVDIIGTVHLTTKRPIVNHAHLEM-----RQIAERTEHVYSVYSRQQSSDIYNQCAQLKIQYLIISLDECTNEVRDDCDLLAIWDDKQPAYQKYPQFCHELLHKNVPSFLKVFANDHYGIIKMFSQSVQINLKHNKMPEMSI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :. : :: : :.*. :.:::::*** :* * .***::***: :.* : :* * . * :::*:***: : *:. : ::::: :: ::*: **: :: : : : .*:: . *** . :.* . . *: : .::: ***:::**: :*: : : :: . : :* * *:***. *:: * *:: . *.: . : . ** * * * ..*:::: :* : : . :: . : : *. : .: **: : :. * *:: * : *::.: .. .* * * *: :. :. . : :* *::. .* : . . : . . :. ::: :. .. * : : * .. . : . . : .: : : * * * *. . : . . . . . . : . : :: * ::: . : : : ::* * : . * : . : : : . .* : : ", "identical_positions": 78, "similar_positions": 199, "identity": "8.25%" }, { "cls_id": "homologset.agr.RGD:1308335", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "G3V606-1", "uniprot_id": "G3V606_RAT", "id": "G3V606-1", "name": "UBX domain-containing protein 10", "aln": "MAIEAPVNFAPPEHSTVVSTAADSYTWQPSSLRMHVIRPKSAKGRKRPNLHLPQGIGDGSHSGLTSSSPPRSSGSP--SNQKREVCATAP-ASQGAPDEMPELL-QQAPIRTASSLNRYPVLPSINRRSSEDGAVDTVSSKTSSLQLSSVQALYQEEARAAVKSSQEDSRTQVCALEKKFIIRTKRQSSSRASNMEEPSDEEPRLLLAVRSPSGQRFVRYFRPSDDLQTVLEVAEQKNKATYQHCIVETMEVPRRRFSDLTKSLQECGILHKSVLGISQEEGEGWP-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BG34-1", "uniprot_id": "UBX10_MOUSE", "id": "Q8BG34-1", "name": "UBX domain-containing protein 10", "aln": "MAIEAPVNFAPPERSTVVSTAGDSSTWQPSSLRMHVIRPKSAKGRKRPNLHRPQGMGDGSPSALSSSPPPRSSGSP--SNQKPGVCATVS-TSQGAPDEMPELLLQQAPTRTASSLNRYPVLPSINRRSLEVGAVDTVASKTSSLQLSSVQALYQEDS------SQEDSRTQVCALEKKFIIRTKRQSSSRASNIEEPSDEEPRLLLAVRSPSGQRFVRYFRPSDDLQTVLEVAEQKNKATYQHCSIETMEVPRRRFSDLTKSLQECGILHKSVLGISQEEGEAWP-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96LJ8-1", "uniprot_id": "UBX10_HUMAN", "id": "Q96LJ8-1", "name": "UBX domain-containing protein 10", "aln": "MATEAPVNIAPPECSTVVSTAVDSLIWQPNSLNMHMIRPKSAKGRTRPSLQKSQGVEVCAH-HIPSPPPAIPYELP--SSQKPGACAPKS-PNQGASDEIPELQ-QQVPTGASSSLNKYPVLPSINRKNLEEEAVETVAKKASSLQLSSIRALYQDETG-TMKTSEEDSRARACAVERKFIVRTKKQGSSRAGNLEEPSDQEPRLLLAVRSPTGQRFVRHFRPTDDLQTIVAVAEQKNKTSYRHCSIETMEVPRRRFSDLTKSLQECRIPHKSVLGISLEDGEGWP-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q0P3Z8-1", "uniprot_id": "UBX10_DANRE", "id": "Q0P3Z8-1", "name": "UBX domain-containing protein 10", "aln": "---------------------------------MHVTRPKSSKGRSRPMITNSSMIYTPSQPSALSPQPPAAAKTKDKSNQSLRSRAILRRSSQPTTDILTEAY--DRPPEEPVSLNRYRVLPSIEKKTS----------------------------------TDNQKCSQCVSRHRKCQHTNARLDVVSDSTPPEESD----LLLAIRTPCGQRFKRSFRPSDQLKGVLSAAEAEFGDRFDNCIIETMDVPRRTFSNLTMTLAQCGVLNKSVLCISHDDSEMDLT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **: ****:***.** : .. : : *. *. . *.*. * ..* :.* :.* : * . ***:* *****:::. ::::. :: : .:* . : . .. * ** ****:*:* **** * ***:*:*: :: .** : : :* :***:**** **:** :* :* : :**** ** ::.* ", "identical_positions": 72, "similar_positions": 62, "identity": "25.09%" }, { "cls_id": "homologset.agr.RGD:1308336", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8C050-1", "uniprot_id": "KS6A5_MOUSE", "id": "Q8C050-1", "name": "Ribosomal protein S6 kinase alpha-5", "aln": "---------------------------------------------------------------------------MEGEGGGSG----------------------------------------------------------------------------------------------------------------GAG-TSGDSGDGGEQLLTVKHELRTANLT-------------------------GHAEKVGIENFELLKVLGTG-----------------------------AYGKVFLVRKISGHDAGKLYAMKVLKKATIVQKAKTTEHTRTERQVLEHIRQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLALEHLHKLGIIYRDIKLENILLDSNGHVVLTDFGLSKEFVADETERAYSFCGTIEYMAPDIVRGGDSGHDKAVDWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSTVAKDLLQRLLMKDPKKRLGCGPRDAEEIKEHLFFEKIKWDDLAAKKVPAPFKPVIRDELDVSNFAEEFTEMDPTYSPAALPQSSERLFQGYSFVAPSILFKRNAAVIDPLQFHMGVDRPGVTNVARSAMMKDSPFYQHYDLDLKDKPLGEGSFSICRKCVHKKTNQAFAVKII--SKRMEANTQKEITALKLCEGHPNIVKLHEVFHDQVAASAQPPGQVVLCSLLLLALLFNRSLTRKPVTWTWLVHSTSQLPPLPPPMPEIVLFILLSDNGQLHTFLVMELLNGGELFERIKRKKHFSETEASYIMRKLVSAVSHMHDVGVVHRDLKPENLLFTD-------ENDNLEIKVIDFGFARLKPPDNQPLKTPCFTLHYAAPELLTHN---GYDESCDLWSLGVILYTMLSGQVPFQS--HDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNVSQEAKDLIQGLLTVDPNKRLKMSGLRYNEWLQDGSQ-------------------------------------------------LSSNPLMTPDILGSS--GAAVHT--------------------CVKATFHAFNKYKR---------EGFCLQNVDK---------APLAKRRKMKRTSTSTETRSSSSESSRSSSSQSHGKTTPTKTLQPSNPTEGSN-------------------------PDTLFQFSD-----------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75582-1", "uniprot_id": "KS6A5_HUMAN", "id": "O75582-1", "name": "Ribosomal protein S6 kinase alpha-5", "aln": "---------------------------------------------------------------------------MEEEGGSSG----------------------------------------------------------------------------------------------------------------GAAGTSADGGDGGEQLLTVKHELRTANLT-------------------------GHAEKVGIENFELLKVLGTG-----------------------------AYGKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHTRTERQVLEHIRQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLALEHLHKLGIIYRDIKLENILLDSNGHVVLTDFGLSKEFVADETERAYSFCGTIEYMAPDIVRGGDSGHDKAVDWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSALAKDLIQRLLMKDPKKRLGCGPRDADEIKEHLFFQKINWDDLAAKKVPAPFKPVIRDELDVSNFAEEFTEMDPTYSPAALPQSSEKLFQGYSFVAPSILFKRNAAVIDPLQFHMGVERPGVTNVARSAMMKDSPFYQHYDLDLKDKPLGEGSFSICRKCVHKKSNQAFAVKII--SKRMEANTQKEITALKLCEGHPNIVKLHEVFHD-----------------------------------------------------------------QLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKLVSAVSHMHDVGVVHRDLKPENLLFTD-------ENDNLEIKIIDFGFARLKPPDNQPLKTPCFTLHYAAPELLNQN---GYDESCDLWSLGVILYTMLSGQVPFQS--HDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNVSQEAKDLIQGLLTVDPNKRLKMSGLRYNEWLQDGSQ-------------------------------------------------LSSNPLMTPDILGSS--GAAVHT--------------------CVKATFHAFNKYKR---------EGFCLQNVDK---------APLAKRRKMKKTSTSTETRSSSSESSHSSSSHSHGKTTPTKTLQPSNPADSNN-------------------------PETLFQFSDSVA--------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZY17-1", "uniprot_id": "D3ZY17_RAT", "id": "D3ZY17-1", "name": "Ribosomal protein S6 kinase", "aln": "---------------------------------------------------------------------------MEGEGGGSG----------------------------------------------------------------------------------------------------------------GAG-TSGDSGDGGEQLLTVKHELRTANLT-------------------------GHAEKVGIENFELLKVLGTGDFSGLVGRCSTSRRETWLLSSLPLLWCLIAYGKVFLVRKISGHDAGKLYAMKVLKKATIVQKAKTTEHTRTERQVLEHIRQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLALEHLHKLGIIYRDIKLENILLDSNGHVVLTDFGLSKEFVADEAERAYSFCGTIEYMAPDIVRGGDSGHDKAVDWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQGMSSVAKDLLQRLLMKDPKKRLGCGPRDAEEIKEHLFFEKINWDDLAAKKVPAPFKPVIRDELDVSNFAEEFTEMDPTYSPAALPQSSERLFQGYSFVAPSILFKRNAAVIDPLQFHMGVDRPGVTNVARSAMMKDSPFYQHYDLDLKDKPLGEGSFSICRKCVHKKTNQAFAVKII--SKRMEANTQKEITALKLCEGHPNVVKLHEVFHD-----------------------------------------------------------------QLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKLVSAVSHMHDVGVVHRDLKPENLLFTD-------ENDNLEIKVIDFGFARLKPPDNQPLKTPCFTLHYAAPELLTHN---GYDESCDLWSLGVILYTMLSGQVPFQS--HDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNVSQEAKDLIQGLLTVDPNKRLKMSGLRYNEWLQDGSQ-------------------------------------------------LSSNPLMTPDILGSS--GAAVHT--------------------CVKATFHAFNKYKR---------EGFCLQNVDK---------APLAKRRKMKRTSTSTETRSSSSESSRSSSSHSHGKTTPTKTLQPSNPTEGSN-------------------------PDTLFQFSD-----------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9V3I5-1", "uniprot_id": "JIL1_DROME", "id": "Q9V3I5-1", "name": "Chromosomal serine/threonine-protein kinase JIL-1", "aln": "MSRLQKQNYEILSGTSTSRLKNHQHPRESESLAYEEPDQMVRNHLNGQLVANGNGKTRKNSNSETMTNGKKSKLNTEGSGSGSGKTLNYNNNNNNNNSISATNGQYTNSSSKTTSASARDYTYRETISPPTPPSPPTTNVADIVCISDAESEDGRDPEREYYDQDMEEDEPNGIEIDESSSSLSKAKSNNAAAAAAAAAAAAAAAASKASSSTTPSYAMPTSNSTPLDLDNEAHQRDLEAVTDLKYYVKLYSDEAVSLNDFKIIRVLGTG-----------------------------AYGRVFLVRKLTRHDAGKLYAMKVLNKITVVQKRKTAEHTKTERVVLEAIQRNPFLVSLHYAFQSSSKLYLVLDFANGGELFTHLYHSENFEESRVRVYIAEVVLALEQLHQLGIIYRDIKLENILLDGEGHIVLSDFGLSKILTAENEYRAHSFCGTLEYMAPEIIRTGPPGHDSAVDWWSVGVLTFELLTGASPFATSDGQVQQSEISRRIQKEQPMIPSSFSANARDFVLKMLEKNPKRRLGGNHRDASEIKEHPFFNGINWQELRTKRRKAPYKPTLTAEDDVQNFSNEFTDQVPEDPECDAPPSRIRLFRGYTYVAPEHLEQMRRDNHCEIQYFN----TGLQNIP----------CRPDDLELGTR-TSNGAYGTCHFVVDSSTDLVFLAKIIPLSKFRPSEVDALISCALDTTNHKNIVSYHGTFRE-----------------------------------------------------------------KCETWIVMEYLSGPELTASIR----MDEDSCREIFLQLVMAVRHIHSKHFIHGDLKPENIMFEN-------RED-RTVKLIDFGSACYNNRFKSWKDKPRYTLDYAPPEMLADANLVTYSPAVDIYGLGATLYTMLVGHRPYRQNEDDVDHSAAAHHELRKRMRRGTFNQRSMRWESASPAFRHLVSWCLQRDPADRPTLSDILDSEWLQYGSNDPDVDIILPQQMVVDLSEDTMEQPTGGMFDDQQQLEFMHDKSAEDEGITLVSEPMDTTVATHESRRNAAAFSSVVAPTTDDEIVHERFDPAFEVQADFYGFDENAPPLPLPEEYYSELPLPEEDRQYIPPPPALIPVEPETTFRRPRTRQQRRTESQLVQPVSVATYEDSKASLRVLMQQLPPPGDNVVARIPKRTHRVVRTLPPTFGTTKREENFYGFSKTAISWRKTRASWRHFCLLINGVQQVLKVRFKKARRVYCLPHIKEEKLDHAYEKPLTFPRPKAQLKRTKREPKVPRPPTRVQPERARAMRQLYQFQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38070-1", "uniprot_id": "YPK3_YEAST", "id": "P38070-1", "name": "Serine/threonine-protein kinase YPK3", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MIFSLDEELHRVSLDDKKNDIKVDYSS--AIYNDINHEQ-----------GSSITYEESINHLSVHSNAIPLNGMSPAHRMRRRSSAYSKFPILTPPNTRRFS-------ITGSDAMRTNTN------------------RLSITPQDIISSNIGENELSRNLHDFKPVRVLGQGAYGKVLLVKDVNTS--------------------------KLYAMKQLRKAEILISQTATDSKREDEDKNDGNNNDNDDGLSKRLERTFAERSILS-------------------------------------------------------------------------------------------------EIEHPNIVKLFYSFHD-----------------------------------------------------------------NSKLYLLLQYIPGGELFYHLKEHGTLDETTVSFYAAEISCALRFLHTKGVVYRDLKPENCLLNQRGHLVLTDFGLSKKSANDSAVDEEDPENVNALYSIIGTPEYCAPEILLGK---AYSQNCDWYSLGCLLYDMLVGKPPYTG---------SNHKVIINKIQQN--KQGPKIPFYLSEGMKDILNALLKKETAKRWNVD----KYWAKTGAN-------------------------------------------------------NKPTKSKKKKSGAARTS---------------------LFTEHFIFRKIDWK------------LLESGQ-----------LQKTTLGPIVPVITDLELAENFDTEFTSMSYEETYTDSKPININSVSKSPD---------------------------MFKGFSYKASGSYLEKYF------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: ** . ..* : :*: . ::..: : : .. : * :::*.: . * *:.: . : : :. :.. : * ..: :* . . :* . : : *:**.: . :* .: .: :: : : .. . *: . * .. :: .: . : * : :: * *:*. . *:: : . ::::: : * ** :: :.* :: *: .:* .:: ****** :: : . . * . . . . * .*..**:* *. * :.** ** ** *: *: : : :::::. . * :.::. * :. .* .:. . * : *:: .. .. .** : : : .. * : * : .: : . : . .. : . . : : : . . . : : ** ", "identical_positions": 61, "similar_positions": 174, "identity": "4.59%" }, { "cls_id": "homologset.agr.RGD:1308337", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5NBY9-1", "uniprot_id": "PATZ1_MOUSE", "id": "Q5NBY9-1", "name": "POZ (BTB) and AT hook-containing zinc finger 1", "aln": "MERVNDASCGPSGCYTYQVSRHSTEMLHNLNQQRKNGGRFCDVLLRVGDESFPAHRAVLAACSEYFESVFSAQLGDGGAADGGPADVGGAAAAPGGGAGGSRELEMHTISSKVFGDILDFAYTSRIVVRLESFPELMTAAKFLLMRSVIEICQEVIKQSNVQILVPPARADIMLFRPPGTSDLGFPLDMTNGAAMAANSNGIAGSMQPEEEAARATGAAIAGQASLPVLPGVDRLPMVAGPLSPQLLTSPFPNVASSAPPLTSKRGRGRPRKANLLDSMFGSPGGLREAGILPCGLCGKVFTDANRLRQHEAQHGVTSLQLGYIDLPPPRLGENGLPISEDPDGPRKRSRTRKQVACEICGKIFRDVYHLNRHKLSHSGEKPYSCPVCGLRFKRKDRMSYHVRSHDGSVGKPYICQSCGKGFSRPDHLNGHIKQVHTSERPHKCQTCNASFATRDRLRSHLACHEDKVPCQVCGKYLRAAYMADHLKKHSEGPSNFCSICNRGFSSASYLKVHVKTHHGVPLPQVSRHQEPILNGGAAFHCARTYGNKEGQKCSHQDLIESSDSYGDLSDASDLKTPEKQSANGSFSCDVAVPKNKMESDGEKKYPCPECGSFFRSKSYLNKHIQKVHVRALGGPLGDLGPALGSPFSPQQNMSLLESFGFQIVQSAFASSLVDPEVDQQPMGPEGK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K420-1", "uniprot_id": "A0A0G2K420_RAT", "id": "A0A0G2K420-1", "name": "BTB/POZ domain zinc finger transcription factor", "aln": "MERVNDASCGPSGCYTYQVSRHSTEMLHNLNQQRKNGGRFCDVLLRVGDESFPAHRAVLAACSEYFESVFSAQLGDGGAADGGPADVGGAAAAPGGGAGGSRELEMHTISSKVFGDILDFAYTSRIVVRLESFPELMTAAKFLLMRSVIEICQEVIKQSNVQILVPPARADIMLFRPPGTSDLGFPLDMTNGAAMAANSNGIAGSMQPEEEAARATGAAIAGQASLPVLPGVDRLPMVAGPLSPQLLTSPFPNVASSAPPLTGKRGRGRPRKANLLDSMFGSPGGLREAGILPCGLCGKVFTDANRLRQHEAQHGVTSLQLGYIDLPPPRLGENGLPISEDPDGPRKRSRTRKQVACEICGKIFRDVYHLNRHKLSHSGEKPYSCPVCGLRFKRKDRMSYHVRSHDGSVGKPYICQSCGKGFSRPDHLNGHIKQVHTSERPHKCQTCNASFATRDRLRSHLACHEDKVPCQVCGKYLRAAYMADHLKKHSEGPSNFCSICNRGFSSASYLKVHVKTHHGVPLPQVSRHQEPILNGGAAFHCARTYGNK-GQKCSHQDLIESSDSYGDLSDASDLKTPEKQSANGSFSCDMAVPKNKMESDGEKKYPCPECGSFFRSKSYLNKHIQKVHVRALGGPLGDLGPALGSPFSPQQNMSLLESFGFQIVQSAFASSLVDPEVDQQPIGPEGK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9HBE1-1", "uniprot_id": "PATZ1_HUMAN", "id": "Q9HBE1-1", "name": "POZ-, AT hook-, and zinc finger-containing protein 1", "aln": "MERVNDASCGPSGCYTYQVSRHSTEMLHNLNQQRKNGGRFCDVLLRVGDESFPAHRAVLAACSEYFESVFSAQLGDGGAADGGPADVGGATAAPGGGAGGSRELEMHTISSKVFGDILDFAYTSRIVVRLESFPELMTAAKFLLMRSVIEICQEVIKQSNVQILVPPARADIMLFRPPGTSDLGFPLDMTNGAALAANSNGIAGSMQPEEEAARAAGAAIAGQASLPVLPGVDRLPMVAGPLSPQLLTSPFPSVASSAPPLTGKRGRGRPRKANLLDSMFGSPGGLREAGILPCGLCGKVFTDANRLRQHEAQHGVTSLQLGYIDLPPPRLGENGLPISEDPDGPRKRSRTRKQVACEICGKIFRDVYHLNRHKLSHSGEKPYSCPVCGLRFKRKDRMSYHVRSHDGSVGKPYICQSCGKGFSRPDHLNGHIKQVHTSERPHKCQTCNASFATRDRLRSHLACHEDKVPCQVCGKYLRAAYMADHLKKHSEGPSNFCSICNRGFSSASYLKVHVKTHHGVPLPQVSRHQEPILNGGAAFHCARTYGNKEGQKCSHQDPIESSDSYGDLSDASDLKTPEKQSANGSFSCDMAVPKNKMESDGEKKYPCPECGSFFRSKSYLNKHIQKVHVRALGGPLGDLGPALGSPFSPQQNMSLLESFGFQIVQSAFASSLVDPEVDQQPMGPEGK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******************************************************************************************:*******************************************************************************************************:********************:************************************.*********.********************************************************************************************************************************************************************************************************************************************************************************************* ******** *******************************:*******************************************************************************************:*****", "identical_positions": 678, "similar_positions": 7, "identity": "98.69%" }, { "cls_id": "homologset.agr.RGD:1308338", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZD18-1", "uniprot_id": "D3ZD18_RAT", "id": "D3ZD18-1", "name": "Serine/threonine-protein kinase 32A", "aln": "---------------------------------------------------------------------------------------------------------------MGANTSSKAPVLDENED-----------------VNFDHFEILRAIGKGSFGKVCIVQKNDTKKMYAMKYMNKQKCVERNEVRNVFKELQIMQGLEHPFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVHFQEDTVKLFICELAMALDYLQSQRIIHRDMKPDNILLDEHGHVHITDFNIAAMLPKETRITTVAGTKPYMAPEMFSS--RKESGYSFAVDWWSLGVTAYELLRGRRPYHIRSSTSSKEIVNMFETAIVTYPSAWSAEMVSLLKKLLEPNPDQRFSHLTDIQNFPYMSDMNWDAVLQKRLIPGFVPTKGRLNCDPTFELEEMILESKPLHKKKKRLAKKEKEMKKCDSPQMCLLQEHLDA-------------------VQKEFIIFN---------REK----VKRDFNQRQANIALEQTK-----------NNTEEE-DGQNNNL-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BGW6-1", "uniprot_id": "ST32A_MOUSE", "id": "Q8BGW6-1", "name": "Serine/threonine-protein kinase 32A", "aln": "---------------------------------------------------------------------------------------------------------------MGANTSSKAPVFDENED-----------------VNFDHFEILRAIGKGSFGKVCIVRKNDTKKMYAMKYMNKQKCVERNEVRNVFKELQIMQGLEHPFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVHFQEDTVKLFICELAMALDYLQSQRIIHRDMKPDNILLDEHGHVHITDFNIAAMLPKETRITTVAGTKPYMAPEMFTS--RKETGYSFAVDWWSLGVTAYELLRGRRPYHIRSSTSSKEIVNMFETAIVTYPSAWSQEMVSLLKKLLEPNPDQRFSHLTDIQNFPYMSDMNWDAVLQKRLIPGFIPTKGRLNCDPTFELEEMILESKPLHKKKKRLAKREKEMKKSDSSQTCLLQEHLDA-------------------VQKEFIIFN---------REK----VKSDFNQRQANLALEQTK-----------NNTEEEEDGQNNNL-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WU08-1", "uniprot_id": "ST32A_HUMAN", "id": "Q8WU08-1", "name": "Serine/threonine-protein kinase 32A", "aln": "---------------------------------------------------------------------------------------------------------------MGANTSRKPPVFDENED-----------------VNFDHFEILRAIGKGSFGKVCIVQKNDTKKMYAMKYMNKQKCVERNEVRNVFKELQIMQGLEHPFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVHFKEETVKLFICELVMALDYLQNQRIIHRDMKPDNILLDEHGHVHITDFNIAAMLPRETQITTMAGTKPYMAPEMFSS--RKGAGYSFAVDWWSLGVTAYELLRGRRPYHIRSSTSSKEIVHTFETTVVTYPSAWSQEMVSLLKKLLEPNPDQRFSQLSDVQNFPYMNDINWDAVFQKRLIPGFIPNKGRLNCDPTFELEEMILESKPLHKKKKRLAKKEKDMRKCDSSQTCLLQEHLDS-------------------VQKEFIIFN---------REK----VNRDFNKRQPNLALEQTK-----------DPQGED--GQNNNL-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VN23-1", "uniprot_id": "Q9VN23_DROME", "id": "Q9VN23-1", "name": "Protein kinase domain-containing protein", "aln": "MEFVDDLCLARILGLLELPDQIAMMQSYERCRPLLGSIWRHRLTRISLNLLEIPLLGDDFRFLLASACQQLHELRISFLGREHFQALIMHCFPNLWLLQVDVLPPFFLCPRQRLQLIQIIPKFHPEDHSLAMGHMLCVKCQSLIPINFDHFQILRAIGKGSFGKVCIVQKRDTGILYAMKYVSRSACEMRGALGGVIKEVELLSSLEHPFLVNLWFSFQDEEDLFMVCDLLTGGDLRYHLQNRVEFSEQSVALLVCELGSALEYLQANRVVHRDIKPDNILLDDAGHAHLTDFNIATRLQKNALACSMSGTKPYMAPEVFLCALDEVAGYSYPVDWWSLGVVAYEMRGNIRPFVVHSNTPLAEIKNILNTP-VHYPRYWSSNFVDLLQRLLSTYPGARISTRQELHQTPMLRNIDFQRVLEKKIKPIYKPPEDHLNCDPCLELEEMIVESRPLHKKKKRLAKQRSAQRDSD-PETALVKEFIVYNRYKELKRKAMEQKENDWQRELELAMANSIVNSLAPIQEKPAACVVHDGDCATASSAVAQLKGESIEFIDRTPSPQIKESAGSRLDMPQSPFQK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * :. ::. :*****:****************:*.** :*****:.:. * *. : .*:**::::..**********:*******:*** *** *********:.*.*.*::* *::*** **:*** :*::***:********: **.*:******: * ::: :::*********:* . : :***:.********.***: . **: ::*.*. ** : ::*. * ** ** ::*.**::**.. *. *:* :::: * : ::::: *::*:: * : * :.:***** :******:**:***********:.. :..* .: .*::*.: : *: : * :** * * : .. *: * * . :: *.. :: ", "identical_positions": 188, "similar_positions": 126, "identity": "32.53%" }, { "cls_id": "homologset.agr.RGD:1308340", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "B1H224-1", "uniprot_id": "PWP3A_RAT", "id": "B1H224-1", "name": "PWWP domain-containing DNA repair factor 3A", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTDAKYVLCRWEKRLWPAKVLARTETSAKNKRKKEFFLDVQILSLKEKIQVKSSAVEALQKSHIENIAAFLASQNE----------VPATPLEELTYRRSLRVALDVLNERTSLSPESHPVENGSTPSQKGKPDADMASQVSSAPSPSFLSEDDQAVAAQCASKRRWECSPKSLSPLSASEEDLRCKVDPKTGLSESGALGTEVPAPTGDESQNGSGSQLDHGQESTTKKRQRNSGEKPARRGKAESGLSKGDSVAESGGQASSCVALASPRLPSQTWEGDPCAGVEGCDPVESSGNIRPLLDSERSKGR------LTKRPRLDGG---RNPLPRHLGTRTVGAVPSRRSCSG---EVTTLRRAGDSDRPEEA-------------------------------------------------DPMSSEESTGFKS-------------VHSLLEEEEEEEEEEEEEEEPPRILLYHE---PRSFEVGMLVWLKYQKYPFWPAVVKSVRRRDKKASVLFIEGNMNPKG---RGITVSLRRLKHFDCKEKHALLDRAKEDFAQAIGWCVSLITDYRVRLGCGSFAGSFLEYYAADISYPVRKSIQQDVLGTRFPQLGKG--------DPEEPMGDSRLGQWRPCRKVLPDRSRAARDKANQKLVEYIVKAKGAESHLRAILHSRKPSRWLKTFLSSNQYVTCMETYLEDEAQLDEVVEYLQGVCRDMDGEMP--ARGSGDRIRFILDVLLPEAIICAISAVEAVDYKTAEQKYLRGPTLSYREKEIFDN------ELLEERNRRRR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6DID5-1", "uniprot_id": "PWP3A_MOUSE", "id": "Q6DID5-1", "name": "PWWP domain-containing DNA repair factor 3A", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTDAKYVLCRWGKRLWPAKVLARTETSAKNKKKKEFFLDVQILSLKEKIQVKSSAVEALQKSHIENIAAFLASQNE----------VPATPLEELTYRRSLRVALDVLNERTSLSPESHPIEDGITLSQKEKTDADVASQVSSAPSPSLLGEDGQAVVAQCASKRRSEYSSKSLLPSSALEDHLRCQVGPKTGLSESG---------AGDKSQDDSGLQLDHGQESTTKKRQRNLGEKPTRRRRSESGLSKGESVLKSQGQASSCVALASPRPPSQTRDEEPCAGVKGCDWVKSSGNIRPLSASERSRGC------PTKRPRLDGG---QNPPTRQLGTRTVGAAPCPRSCSG---EVTMLCSAGAGDKPEE--------------------------------------------------DPVSSEESTGFKS-------------THSLLEEEEEEEEE------PPRILLYHE---PRSFEVGMLVWLKYQKYPFWPAVVKSVRRRDKKASVLFIEGNMNPKG---RGITVSLRRLKHFDCKEKHALLDRAKEDFAQAIGWCVSLITDYRVRLGCGSFAGSFLEYYAADISYPVRKSIQQDVLGTRFPQLGKG--------DPEEPVGDSQLGQWRPCRKVLPDRSRAARDRANQKLVEYIVKAKGAESHLRAILHSRKPSRWLKTFLSSSQCVTCMETYLEDEAQLDEVVEYLQGVCRDMDGQVP--ERGSGDRIRFILDVLLPEAIICAISAVEAVDYKTAEQKYIRGPTLSYREKEIFDN------ELLEERNRRRR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q2TAK8-1", "uniprot_id": "PWP3A_HUMAN", "id": "Q2TAK8-1", "name": "PWWP domain-containing DNA repair factor 3A", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MADAKYVLCRWEKRLWPAKVLARTATSTKNKRRKEYFLAVQILSLEEKIKVKSTEVEILEKSQIEAIASSLASQNE----------VPAAPLEELAYRRSLRVALDVLSEGSIWSQESSAGTGRADRSLRGKPMEHVSSPCDSN-SSSLPRGD---VLGSSRPHRRRPCVQQSLSSSFTCEKDPECKVDHKKGLRKSENPRGPLVLPAGGGAQDESGSRIHHKNWTLASKRGGNSAQKASLCLNG-SSLSEDDTERDMGSKGG---SWAAPSLPSGVREDDPCANAEGHDPGLPLGSLTAPPAPEPSACSEPGECPAKKRPRLDGS---QRPPAVQLEPMAAGAAPSPGPGPGPRESVTPRSTARLGPPPSHASADATR-------------------------------CLPCPDSQKLEKECQSSEESMGSNS-------------MRSILEEDEEDEEP-------PRVLLYHE---PRSFEVGMLVWHKHKKYPFWPAVVKSVRQRDKKASVLYIEGHMNPKM---KGFTVSLKSLKHFDCKEKQTLLNQAREDFNQDIGWCVSLITDYRVRLGCGSFAGSFLEYYAADISYPVRKSIQQDVLGTKLPQLSKG--------SPEEPVVGCPLGQRQPCRKMLPDRSRAARDRANQKLVEYIVKAKGAESHLRAILKSRKPSRWLQTFLSSSQYVTCVETYLEDEGQLDLVVKYLQGVYQEVGAKVL--QRTNGDRIRFILDVLLPEAIICAISAVDEVDYKTAEEKYIKGPSLSYREKEIFDN------QLLEERNRRRR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PVE2-1", "uniprot_id": "A0A8M1PVE2_DANRE", "id": "A0A8M1PVE2-1", "name": "", "aln": "MVAGMSSSDESLKRQRNPHRTCRTDSTQVNEPVSGGTESITHNKRTTAPQDLILVKSCGRRATENKPQAANQNAPPCLRKSRHQVTNINGCVSKKSHQPEQVLPRKIATPKYQIKTAYKGRRKKNVEASEKKVAASKAKLDVLDNLCSEQHLSSQKPKRTHHQNSKRTQNHQTPSDVSTGVYTCTTLSPCRCKEDSCCHTNRPQAPLQDRLQFTSLLSSTSNSDLKSLSPQTGQNSCVPHSEPDVLKSSLEKRPPTDASPSPQRARGRPKGNNNKVQEDPSSFSPVKHSRESTECPVEYPKRFLHSSSDLQCLSPQTAENSFAPNNHQNARKSSLKKRPPADALPSPQRARGRPKRNNNKVQEDPSSSSPVKHSRESTECPVEYPKRFLHSSSDLQCLSPQTAENTCAPNNYQNARKSRLKKRPPADALPSPQRARGRPKGSKNKKVQERPSASPSEKYSRKHEMPLVESCSQKHLSSPWNSHLQPLKPKTDDNSFAPYNDPNARESQQEKRPPADASSSTPSRPRAGPKGSTTKKIQKKSSISPPVKCSRKFTECLAASHTPKQKRLQSSPLLSSTPSSHHLPLIPLRADNNPTPNATKSRLKKRPPADASPSTPQRPRGRPKGSMNKKVQEGASVSPPVKRSRKFTECLAESHTPKQKRLKSSPLLSSTPSSHLQPLTSKREDNNPAPNATKSRLEKRPPADASPSTPQRTRGRSKGSTNKKVQEGASVSPPVKRSRKSTEFPAEMQTLSSPCSENQEPEPNESDQTMSSDLSIELSLHEDPHLLNHSLFMQEEKDDQDDDDDDEELPSFLGQDSKKPLSISEGLCVWCKMWKYPYWPAVVKSVNRKNKKASIIFIDCDLSDQKRAKKGFTVSLRNLKPFDCEDYEKLVDMAKEKYGSAITWSVELISDYRIRIGCGSFSGSFIEYCAADISCPVRRKYSEGKSVLTFPSQEILGEKCDISENSAEDICAEDQDELLSQKRNLPDRAKAARTRANEQLVDFIIRGK-VENHLLAIIS--ESSAWMQALQKPFRQVVCPVLYLEDEGQVDKVYQYLHDLCETAPQINTSPENVQVVRVRLILDVLLPKAIIYAIAGVHNLSLEKAEEKYHKGPRFSNRERQEFDMMIERQMKLKEITQRHRR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :** * * : .: .*:.. ::. :. ::: .*: :: *. . * .: ** . * * : : *. . :.* . * .. . . .::* .* .. * . .: * : . : . . :.. * . :. . : . * : ....: * .:. :. .: ** . . . ..: . . . *: **... . . :* . : . . : * . . . : .*::: . . :*:: ::*:::: :* :: * *:. *: ** * ***:********.:::****:::*: .:. : :*:****: ** ***:: . *:: *:*.: . * *.*.**:***:*:*****:***:** ***** ***:. .:. :*. .. * : .: . :: ****::*** :**::**::*::.* .*.** **: :.* *:::: .. : *.* *****.*:* * :**:.: . . . *:*:*******:*** **:.*. :. :.**:** :** :* **:: ** :* * :*:**", "identical_positions": 160, "similar_positions": 215, "identity": "14.0%" }, { "cls_id": "homologset.agr.RGD:1308341", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q01965-1", "uniprot_id": "LY9_MOUSE", "id": "Q01965-1", "name": "T-lymphocyte surface antigen Ly-9", "aln": "MADLKRYWCDWALGPLSENPRMSQQQIFSPILWIPLLFLLMGLGASGKETPPTVISGMLGGSVTFSLNISKDAEIEHIIWNCPPKALALVFYKKD-ITILDKGYNGRLKVSEDGYSLYMSNLTKSDSGSYHAQINQKNVILTTNKEFTLHIYEKLQKPQIIVESVTPSDTDSCTFTLICTVKGTKDSVQYSWTREDTHLNTYDGSHTLRVSQSVCDPDLPYTCKAWNPVSQNSSQPVRIWQFCT--GASRRKTAAGKTVVGILGEPVTLPLEFRATRATKNVVWVFNTSVISQERRGAATAD-SRRKPKGSEERRVRTSDQDQSLKISQLKMEDAGPYHAYVCSEASRDPSVRHFTLLVYKRLEKPSVTKSPVHMMNGICEVVLTCSVDGGGNNVTYTWMPLQNKAVMSQGKSHLNVSWESGEHLPNFTCTAHNPVSNSSSQFSSGTICSGPERNKRFWL-LLLLVLLLLMLIGGYFILRKKKQCSSLATRYRQAEVPAEIPETPTGHGQFSVLSQRYEKLDMSAKTTRHQPTPTSDTSSESSATTEEDDEKTRMHSTANSRNQVYDLVTHQDIAHALAYEGQVEYEAITPYDKVDGSMDEEDMAYIQVSLNVQGETPLPQKKEDSNTIYCSVQKPKKTAQTPQQDAESPETPTYENFT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GJS8-1", "uniprot_id": "A0A8I6GJS8_RAT", "id": "A0A8I6GJS8-1", "name": "", "aln": "MADLKRYWCERALDAFSEKTRKSQQQIFSPILWIPLLFLLMGLGASGKETPPRVISGILGGSVTFPLNISINAEIELITWTYLSKTLVLAITSRSGITILLKEYSGRLNISQDGYSLCMSNLTKSDSGSYQAQIIQKNVDHTVRNEFILHIYEQLQEPQVTVKSMTSSENDSCTVTLICTVNGSKDGVQYSWIQKDTHNKTSHESHILRVSPSACDPDLPYTCTARNPVSQNSSQPVRVRQFCT--GTSRKKTTG-KTVIGILGEPVTLSLEFPASEETKNVVWVFNTSVISQEPKGAATVDPHRHKSKSSEERRLRISDQDSSLKISQLKMEDTGPYHAYVCSETSRGPSVRHFTLLVYQRLKKPNVTQSPVHMTNGICEVVLTCSVEGGEKDVRYTWMPLQKETVMSQGKSHLNVSWKIGERLPNFTCTTHNPVSNSSRQLSSGSLCSGPERNKRLWI-LLLLGLFLGMLIGGCFILKKRKLCSSLAIRNSQAKVPAEIPETPAGHIGFSVLSQQYEKLDMPAKTIRHHSTSTSDTSSESSATTEEDDEKTRMHSTVNGRSQVYDLFTQEDIAHDLASEGQAEYEAVSPDDKVAKSMDEEDTAYTQESLIVQGENPLPQKKEGSNTIYCSLQKHKTMVQTPQQDTESPETPTYENFT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9HBG7-1", "uniprot_id": "LY9_HUMAN", "id": "Q9HBG7-1", "name": "T-lymphocyte surface antigen Ly-9", "aln": "MVAPKSHTDDWAPGPFSSKPQRSQLQIFSSVLQTSLLFLLMGLRASGKDSAPTVVSGILGGSVTLPLNISVDTEIENVIWIGPKNALAFARPKEN-VTIMVKSYLGRLDITKWSYSLCISNLTLNDAGSYKAQINQRNFEVTTEEEFTLFVYEQLQEPQVTMKSVKVSENFSCNITLMCSVKGAEKSVLYSWTPREPHASESNGGSILTVSRTPCDPDLPYICTAQNPVSQRSSLPVHVGQFCTDPGASRGGTTG-ETVVGVLGEPVTLPLALPACRDTEKVVWLFNTSIISKEREEAATAD-PLIKSRDPYKNRVWVSSQDCSLKISQLKIEDAGPYHAYVCSEASSVTSMTHVTLLIYRRLRKPKITWSLRHSEDGICRISLTCSVEDGGNTVMYTWTPLQKEAVVSQGESHLNVSWRSSENHPNLTCTASNPVSRSSHQFLSENICSGPERNTKLWIGLFLMVCLLCVGIFSWCIWKRKGRCSVPAFCSSQAEAPADTPEPTAGHTLYSVLSQGYEKLDTPLRPARQQPTPTSDSSSDSNLTTEEDEDRPEVHKPISGRYEVFDQVTQEGAGHDPAPEGQADYDPVTPYVTEVESVVGENTMYAQV-FNLQGKTPVSQKEESSATIYCSIRKPQVVPPPQQNDLEIPESPTYENFT", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. * : : * ..:*.:.: ** ****.:* .******** ****::.* *:**:******:.**** ::*** : * ::*.:. ... :**: * * ***.::: .*** :**** .*:***:*** *:*. *..:** *.:**:**:**: ::*:. *:. **..**:*:*:*::..* *** .:.* . . . * ** : ******* *.* *****.** **:: **** *:** *:. :**:*:*******.* : * . *::***:****:**:* . ***.* *.:.. :.*: *.** ********:**:**********:* .*: *.***:*:**.**.:* * * :***.: *****:.* : * *** ***:::*:***:*******. .*. **:***: ****.** *: * .:*******.::*: *:*: :* : * . * ::: ** * **:.**: **..:** :***** ***** . :. *::.*.***:**:*. *****:::..:*.. ..* :*:* .*::. .* * ***.:*:.::* . *: *: * * : :**:.*:.**:*.* *****::* : . *:* * **:*******", "identical_positions": 313, "similar_positions": 202, "identity": "47.5%" }, { "cls_id": "homologset.agr.RGD:1308343", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZFQ5-1", "uniprot_id": "D3ZFQ5_RAT", "id": "D3ZFQ5-1", "name": "", "aln": "--------MRTYHFLQLIVWTWIFQMVDNSPLQGKDNI----------------------HLR-KRIVNLKKDDGKMLHRTKRGWMWN---QFFLLEEYTGTDTQYVGKLHTDQDKGDGNLKYILTGDGAG-NLFVIDENTGDIHAAKKLDREE--KSLYILRAKAIDRKTGRQVEPESEFIIKIHDINDNEPKFTKDLYTASVPEMSGVGTSVIQVTATDADDANYGNSAKVVYSILQGQ--PYFSVDPESGIIKTALPDMSRENR----------------EQYQVVIQAKDMGGQMG----------------GLSGTTTVNITLTDVNNNPPR---------------FPQSTYQFNSLE-------------SAPLGTHLGRIKANDPDTGENAELEYSISEGEGSDMFDVITDK-------------------------------------------DTQEGIITVKQNLDFEKKMLYTLRVDASNTHPDPRFLHLGP-----------------------------------------------------------------------------------------------------FKDSAMVKISVEDVDEPPVFSKLSYLMEVDEDVKEGSIIGQVTAYDPDAMN-NIIKYSVDRHTDMDRVFSIHSENGSIFTLKPLDRESSPWHN-----ITVTATEINNPKQSSQIAVFIRILDINDHAPEFAMYYETFVCENAKSGQLIQTISVMDKDDPPRG-------------------------------------------------------------------------------------------------------------HKFFFEPVPEFPLNPN-----------------------------------------------------------------------------------------------------FTIVDNKDNTAGIITRKDG---------------------------------------------YSRNKMNTYLLPVLIFDN------------------------------------------------------------------------------------------------------------------------------------------------DYPIQSSTGTLTIRVCACDNQGNMQS----------------------------------------------------------------------CNAEALMLAAGLSTGALIAILLCVVILLTLIVLFAALKRQRKKEPLIISKDDVRDNIVTYNDEGGGEEDTQAFDIGTLRNPEAREDSKLRRDVMPETIFQIRRTVPLWENIDVQDFIHRRLKENDSDPSAPPYDSLATYAYEGNDSVANSLSSLESLTADCNQDYDYLSDWGPRFKKLAEMYGGDDSDRD-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70407-1", "uniprot_id": "CADH9_MOUSE", "id": "P70407-1", "name": "Cadherin-9", "aln": "--------MRTYSCLQLVIWTCIFHMVDNSTLQGKDSS----------------------HFL-RRIVNLKKDEGKMLHRAKRGWMWN---QFFLLEEYTGTDTQYVGKLHTDQDKGDGNLKYILTGDGAG-NLFVIDENTGDIHAAKRLDREE--KSLYILRAKAIDRKTGRQVEPESEFIIKIHDINDNEPKFTKDLYTASVPEMSGVGTSVIQVTATDADDANYGNSAKVVYSILQGQ--PYFSVDPESGIIKTALPDMSRENK----------------EQYQVVIQAKDMGGQMG----------------GLSGTTTVNITLTDVNNNPPR---------------FPQSTYQFNSLE-------------SAPLGTHLGRIKANDPDMGENAELEYSIAEGEGSDMFDVITDK-------------------------------------------DTQEGIITVKQNLDFEKKMLYTLRVDASNTHPDPRFLHLGP-----------------------------------------------------------------------------------------------------FKDSAMVKISVEDVDEPPVFSKLSYLMEVDEDVKEGSIIGQVTAYDPDAMN-NIIKYSVDRHTDMDRVFSIHSENGSIFTLKPLDRESSPWHN-----ITITATEINNPKQSSQIPVFIRILDINDHAPEFATYYETFVCENAKSGQLIQTISVMDKDDPPRG-------------------------------------------------------------------------------------------------------------HKFFFEPVPEFPLNPN-----------------------------------------------------------------------------------------------------FTIVDNKDNTAGIVTRKDG---------------------------------------------YSRNKMNTYLLPVLIFDN------------------------------------------------------------------------------------------------------------------------------------------------DYPIQSSTGTLTIRVCACDNLGNMQS----------------------------------------------------------------------CNAEALMLAAGLSTGALIAILLCVVILLTLIVLFAALKRQRKKEPLIISKDDVRDNIVTYNDEGGGEEDTQAFDIGTLRNPEAREDSKLRRDVMPETIFQIRRTVPLWENIDVQDFIHRRLKENDSDPSAPPYDSLATYAYEGNDSVANSLSSLESLTADCNQDYDYLSDWGPRFKKLAEMYGGNDSD-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9ULB4-1", "uniprot_id": "CADH9_HUMAN", "id": "Q9ULB4-1", "name": "Cadherin-9", "aln": "--------MRTYHYIPLFIWTYMFHTVDTILLQEKPNS----------------------YLSSKKIAGLTKDDGKMLRRTKRGWMWN---QFFLLEEYTGTDTQYVGKLHTDQDKGDGNLKYILTGDGAG-SLFVIDENTGDIHAAKKLDREE--KSLYILRAKAIDRKTGRQVEPESEFIIKIHDINDNEPKFTKDLYTASVPEMSGVGTSVIQVTATDADDANYGNSAKVVYSILQGQ--PYFSVDPESGIIKTALPDMSRENR----------------EQYQVVIQAKDMGGQMG----------------GLSGTTTVNITLTDVNNNPPR---------------FPQSTYQFNSPE-------------SVPLGTHLGRIKANDPDVGENAEMEYSIAEGDGADMFDVITDK-------------------------------------------DTQEGIITVKQNLDFENQMLYTLRVDASNTHPDPRFLHLGP-----------------------------------------------------------------------------------------------------FKDTAVVKISVEDIDEPPVFTKVSYLIEVDEDVKEGSIIGQVTAYDPDARN-NLIKYSVDRHTDMDRIFGIHSENGSIFTLKALDRESSPWHN-----ITVTATEINNPKQSSHIPVFIRILDINDHAPEFAMYYETFVCENAKPGQLIQTVSVMDKDDPPRG-------------------------------------------------------------------------------------------------------------HKFFFEPVPEFTLNPN-----------------------------------------------------------------------------------------------------FTIVDNKDNTAGIMTRKDG---------------------------------------------YSRNKMSTYLLPILIFDN------------------------------------------------------------------------------------------------------------------------------------------------DYPIQSSTGTLTIRVCACDNQGNMQS----------------------------------------------------------------------CTAEALILSAGLSTGALVAILLCVLILLILVVLFAALKRQRKKEPLIISKDDVRDNIVTYNDEGGGEEDTQAFDIGTLRNPEAREDSKLRRDVMPETIFQIRRTVPLWENIDVQDFIHRRLKENDADPSAPPYDSLATYAYEGNDSIADSLSSLESLTADCNQDYDYLSDWGPRFKKLADMYGGDDSDRD-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24298-1", "uniprot_id": "CADE_DROME", "id": "Q24298-1", "name": "DE-cadherin", "aln": "MSTSVQRMSRSYHCINMSATPQAGHLNPAQQQTHQQHKRKCRDLGRRLIPARLLLGVIVAISLLSPALALHSPPDKNFSGDNRKPAFKNCAGYAPKVKEEQPENTYVLTVEAVDPDPDQVIRYSIVQSPFERPKFFINPSTGVIFTTHTFDRDEPIHEKFVFVTVQATDNGLPPLDDVCTFNVTIEDINDNAPAFNKARYDESMSENAQPDAVVMTISASDFDDG---NNSLVEYEILRERDFQYFKIDKESGIIYLKRPIDKRPGQSYAIIVRAYNVVPDPPQDAQIEVRIRVVESSIKPPSFVNPIDTPIYLKENLKNFTHPIATLRAVSNMPDKPEVIFELNTGRTEQTNSKNTFVFNQIGNEVTISLGKTLDYEAITDYTLTMIVRNTHELGTEHQIKIQVEDVNDNIPYYTEVKSGTILENEPPGTPVMQVRAFDMDGTSANNIVSFELADNREYFTIDPNTGNITALTTFDREERDFYNVKVIASDNSPSSLFDNGEPNRGHQVFRISIGDKNDHKPHFQQDKYLAERLLEDANTNTEVIEVKAEDEDNASQILYSIESGNVGDAFKIGLKTGKITVNQKLDYETITEYELKVRAFDGIYDDYTTVVIKIEDVNDNPPVFKQDYSVTILEETTYDDCILTVEAYDPDIKDRNADQHIVYSIHQNDGNRWTIDNSGCLRLVKTLDRDPPNGHKNWQVLIKANDEDGVGTTVSTVKEVTVTLKDINDNAPFLINEMPVYWQENRNPGHVVQLQANDYDDTPGAGNFTFGIDSEATPDIKTKFSMDGDYLHANVQFDREAQKEYFIPIRISDSGVPRQSAVSILHLVIGDVNDNAMSEGSSRIFIYNYKGEAPETDIGRVFVDDLDDWDLEDKYFEWKDLPHDQFRLNPSTGMITMLVHTAEGEYDLSFVVTEDSMFVPRHSVDAYVTVVVRELPEEAVDKSGSIRFINVTKEEFISVPRDFQSPDALSLKDRLQLSLAKLFNTSVSNVDVFTVLQNENHTLDVRFSAHGSPYYAPEKLNGIVAQNQQRLENELDLQMLMVNIDECLIEKFKCEESCTNELHKSSVPYMIYSNTTSFVGVNAFVQAQCVCEAPLMRRCLNGGSPRYGENDVCDCIDGFTGPHCELVSVAFYGSGYAFYEPIAACNNTKISLEITPQIDQGLIMYLGPLNFNPLLAISDFLALELDNGYPVLTVDYGSGAIRIRHQHIKMVADRTYQLDIILQRTSIEMTVDNCRLSTCQTLGAPIGPNEFLNVNAPLQLGGTPVDLEQLGRQLNWTHVPNQKGFFGCIRNLTINEQTYNLGMPSVFRNIDSGCQQSVAVAFSFGIDRNFIIAIIVCLALLLIILLAVVVQKKQ-KNGWHEKDIDDIRETIINYEDEGGGERD-TDYDLNVLRTQPFYEEKLYKDPHALQGNMRDPNDIP-----DIADFLGDKKENCDRDVGATTVDDVRHYAYEGDGNSDGSLSSLASCTDDGDLNFDYLSNFGPRFRKLADMYGEEPSDTDSNVDDDQGWRI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:* : : . : : * . .* : :* :: : : .:. ** .:.: : . * ::* :. . *.*: .** *.::: :**:* :. ::: : : :: . * :.*.***** * *.* * *:.* : .: *: ::*:* **. *.: * *.**: : **.:* ***** * .* .: :: *: :: : : ..: .*.. * ** *.* * : .:.*: **. .. . * * * : * : ::: .: : :. : . ... *.: * **. .:* *:: :*.::* **:. *.. * : * :.* : * *.:**::: * . * .* : : *:.. .. * * ***** : * :: * : * .:.*.: :*.***:.. *: *. . : ... *: * : : ****:** : .: ** :.*:::* : .* * * .:: * :* ***. **:::*:::* .: .* . *:: . :* :*:.* * :* :: :*: * .. .: : : *: :: *:. . ::**::*: :** ::: ... *:* *: . **:*:.*:.*:******.* :*:..**. *:. : : :: . :* *: **: : :: * * .*.. *.: *****:.. .***** * * * : ::****::****:***:*** : ** ", "identical_positions": 200, "similar_positions": 273, "identity": "13.18%" }, { "cls_id": "homologset.agr.RGD:1308346", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q66H62-1", "uniprot_id": "CYLD_RAT", "id": "Q66H62-1", "name": "Ubiquitin carboxyl-terminal hydrolase CYLD", "aln": "MSSGLWNQEKVTSPYWEERLFYLLLQECSVTDKQTQKLLRVPKGSIGQYIQDRSVGHSRVPSAKGKKNQIGLKILEQPHAVLFVDEKDVVEINEKFTELLLAITNCEERLSLFRNRIRLSKGLQVDVGSPVRVQLRSGEEKFPGVVRFRGPLLAERTVSGIFFGVELLEEGRGQGFTDGVYQGKQLFQCDEDCGVFVALDKLELIEDDDNGLESDFAGPGD-TVQVEPPPLEINSRVSLKVGESTESGTVIFCDVLPGKESLGYFVGVDMDNPIGNWDGRFDGVQLCSFASVESTVLLHINDIIP---DSVTQERRPPKLAFMSRGVGDKGSSSHNKPKVTGSTSDPGSRNRSELFYTLNGSSVDSQQQSKSKNPWYIDEVAEDPAKSLTEMSSDFG-HSSPPPQPPSMNSLSSENRFHSLPFSLTKMPNTNGSMAHSPLSLSVQSVMGELNSTPVQESPPMPSSS--GNAHGLEVGSLAEVKEN---PPFYGVIRWIGQPPG-LSDVLAGLELEDEC----AGCTDGTFRGTRYFTCALKKALFVKLKSCRPDSRFASLQP--VSNQIERCNSLAFGGYLSEVVEENTPPKMEK--EGLEIMIGKKKGIQGHYNSCYLDSTLFCLFAFSSALDTVLLRPKEKNDVEYYSETQELLRTEIVNPLRIYGYVCATKIMKLRKILEKVEAASGFTSEEKDPEEFLNILFHDILRVEPLLKIRSAGQKVQDCNFYQIFMEKNEKVGVPTIQQLLEWSFINSNLKFAEAPSCLIIQMPRFGKDFKLFKKIFPSLELNITDLLEDTPRQCRICGGLAMYECRECYDDPDISAG-KIKQFCKTCSTQVHLHPRRLNHTYHPVSLPKDLPDWDWRHGCIPCQKMELFAVLCIETSHYVAFVKYGKD-DSAWLFFDSMADRDGGQNGFNIPQVTPCPEVGEYLKMS---LEDLHSLDSRRIQGCARRLLCDAYMCMYQSPTMSLYK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80TQ2-1", "uniprot_id": "CYLD_MOUSE", "id": "Q80TQ2-1", "name": "Ubiquitin carboxyl-terminal hydrolase CYLD", "aln": "MSSGLWSQEKVTSPYWEERIFYLLLQECSVTDKQTQKLLKVPKGSIGQYIQDRSVGHSRVPSTKGKKNQIGLKILEQPHAVLFVDEKDVVEINEKFTELLLAITNCEERLSLFRNRLRLSKGLQVDVGSPVKVQLRSGEEKFPGVVRFRGPLLAERTVSGIFFGVELLEEGRGQGFTDGVYQGKQLFQCDEDCGVFVALDKLELIEDDDNGLESDFAGPGD-TMQVEPPPLEINSRVSLKVGESTESGTVIFCDVLPGKESLGYFVGVDMDNPIGNWDGRFDGVQLCSFASVESTILLHINDIIP---DSVTQERRPPKLAFMSRGVGDKGSSSHNKPKVTGSTSDPGSRNRSELFYTLNGSSVDSQQ-SKSKNPWYIDEVAEDPAKSLTEMSSDFG-HSSPPPQPPSMNSLSSENRFHSLPFSLTKMPNTNGSMAHSPLSLSVQSVMGELNSTPVQESPPLPISS--GNAHGLEVGSLAEVKEN---PPFYGVIRWIGQPPG-LSDVLAGLELEDEC----AGCTDGTFRGTRYFTCALKKALFVKLKSCRPDSRFASLQP--VSNQIERCNSLAFGGYLSEVVEENTPPKMEK--EGLEIMIGKKKGIQGHYNSCYLDSTLFCLFAFSSALDTVLLRPKEKNDIEYYSETQELLRTEIVNPLRIYGYVCATKIMKLRKILEKVEAASGFTSEEKDPEEFLNILFHDILRVEPLLKIRSAGQKVQDCNFYQIFMEKNEKVGVPTIQQLLEWSFINSNLKFAEAPSCLIIQMPRFGKDFKLFKKIFPSLELNITDLLEDTPRQCRICGGLAMYECRECYDDPDISAG-KIKQFCKTCSTQVHLHPRRLNHSYHPVSLPKDLPDWDWRHGCIPCQKMELFAVLCIETSHYVAFVKYGKD-DSAWLFFDSMADRDGGQNGFNIPQVTPCPEVGEYLKMS---LEDLHSLDSRRIQGCARRLLCDAYMCMYQSPTMSLYK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NQC7-1", "uniprot_id": "CYLD_HUMAN", "id": "Q9NQC7-1", "name": "Ubiquitin carboxyl-terminal hydrolase CYLD", "aln": "MSSGLWSQEKVTSPYWEERIFYLLLQECSVTDKQTQKLLKVPKGSIGQYIQDRSVGHSRIPSAKGKKNQIGLKILEQPHAVLFVDEKDVVEINEKFTELLLAITNCEERFSLFKNRNRLSKGLQIDVGCPVKVQLRSGEEKFPGVVRFRGPLLAERTVSGIFFGVELLEEGRGQGFTDGVYQGKQLFQCDEDCGVFVALDKLELIEDDDTALESDYAGPGD-TMQVELPPLEINSRVSLKVGETIESGTVIFCDVLPGKESLGYFVGVDMDNPIGNWDGRFDGVQLCSFACVESTILLHINDIIPALSESVTQERRPPKLAFMSRGVGDKGSSSHNKPKATGSTSDPGNRNRSELFYTLNGSSVDSQPQSKSKNTWYIDEVAEDPAKSLTEISTDFD-RSSPPLQPPPVNSLTTENRFHSLPFSLTKMPNTNGSIGHSPLSLSAQSVMEELNTAPVQESPPLAMPP--GNSHGLEVGSLAEVKEN---PPFYGVIRWIGQPPG-LNEVLAGLELEDEC----AGCTDGTFRGTRYFTCALKKALFVKLKSCRPDSRFASLQP--VSNQIERCNSLAFGGYLSEVVEENTPPKMEK--EGLEIMIGKKKGIQGHYNSCYLDSTLFCLFAFSSVLDTVLLRPKEKNDVEYYSETQELLRTEIVNPLRIYGYVCATKIMKLRKILEKVEAASGFTSEEKDPEEFLNILFHHILRVEPLLKIRSAGQKVQDCYFYQIFMEKNEKVGVPTIQQLLEWSFINSNLKFAEAPSCLIIQMPRFGKDFKLFKKIFPSLELNITDLLEDTPRQCRICGGLAMYECRECYDDPDISAG-KIKQFCKTCNTQVHLHPKRLNHKYNPVSLPKDLPDWDWRHGCIPCQNMELFAVLCIETSHYVAFVKYGKD-DSAWLFFDSMADRDGGQNGFNIPQVTPCPEVGEYLKMS---LEDLHSLDSRRIQGCARRLLCDAYMCMYQSPTMSLYK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B6V2-1", "uniprot_id": "A0ACD6B6V2_DANRE", "id": "A0ACD6B6V2-1", "name": "Ubiquitin carboxyl-terminal hydrolase CYLD", "aln": "MSSTLWSQEKPGGSFRDDWRFYIVVKECTVE-RPGQKTLRIPRGSLGQACQERNSLGRTIPASKGKRS---LRILDQTNVVVSVDERDVMELEEKLAELLFPITNCEERYSLLCNRSRLDRARDINCGSKVRVQLRSGDEPLPGVVRFKGALLPDRALSGIWFGVELLEEGRGQGFTEGSYQGQQLFRCEDECGVFVALDKLELWEDEELEVDRVTLEDNDPEEEGEAPPLEINSRVLVQTREGPERGTVIFCDLLPGNESLGYYVGVDMDNPIGDWDGIIDGKQLCNFASLEHTRLVPICDVMP---EYSMQDQRLPK-VFACRGGNDK-PVSQSKPKSKGLGLQPGSRSKSEFYYTLNGSSVDHPAQSKAKSTWYIDEVGEDPAKSLTDMPPDFNPSSSPSRAPPTTTSLSNDNKFHSLPFSLSRKVGPNGSMSHGPLSLSAGSVMGEQPELLPAATPLQRASSPPQGQPGLEVGSMVEVKEN---PPLCGVIRWVGLPPG-LQESLAGLELEEEC----VGCTDGTFKGIRYFTCPPKKALFVKLKCCRPDSRFPSLHH--SPNPIERCNSIAFGGYLSEVVNENTPPRTEN--DGLEVMVGKKKGIQGHYNSCYLDSTLFCLFSFSSVLDTVLLRPRSKTDVEYYKETQELLRTEIVNPLRIHGYVCATKIMKLRRILEKVEAASGFTSEEKDPEEFLNILFHHILRVDPLLRLRSAGQKVQDCYFYQIFMDKKDKVMVPTSQQLLEWSFINSDLKFAEAPSCLIIQMPRFGKDFKMFNKIFPSLELDITDLLDDTPRECRICGGLALYECRECYEDYDITPG-KIKQFCEKCNTQVHLHPRRKTHRYVKLSVPKELHESVWRQGSYPHQQMELFAVLCIETSHYVAFVKYGSA-DSAWLFFDSMADRDGGQNGFNIPQVSRCPEVGEYLKMT---PEELHALDPKNIQGYARRLLCDAYMCMYQSPTMSLYK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IPC5-1", "uniprot_id": "Q8IPC5_DROME", "id": "Q8IPC5-1", "name": "ubiquitinyl hydrolase 1", "aln": "-----------------------------------------------------------------------------------MNSKSDYEAEK---EKKLTITN------------------------------RFGDS----------------------------------------------------------LENYELSNES-----------------------EHKTHVYPKKIPNRKNGILKNTDANHSAVDNQHLEDVDLADILG-----------------------------------------------------------TNWPKRAGPAA-----------MILNNK-------SKTDPSNSVDLILK-PASPILKIEPEEP-----------------------LRFTIADY------------------------------QPLIEIPG-----TELAIGSLVEVSNPGVCEDLYGVVRWIGIPPGPQKNVLVGIEVEDESNLKNVVASDGRHNGVRLFTCHDGRAIFVPANRCTADRRFADVDNSISANRVSSNHAKKFGVADCPAIYGSIPPLQIHNSDELASICGKFKGIQGHHNSCYLDATLFSMFTFTSVFDSILYRRPGPQDIRNYSEVQKVLRDEIVNPLRKNVFVRSDRVMKLRELLDQLSSVSGLTCEEKDPEEFLNSLLSQIMRVEPFLKLSSG----QDSYFYQLFVEKDEKLTLPSVQQLFEQSFHSSDIKLKEVPSCFIIQMPRFGKNYKMYPRILPSQVLDVTDIIENSPRQCSLCGKLAEYECRDCFGSLQAGSGLECTAFCPKCLKTFHSHIKRTNHVSKKIYSPKEF-KIMAEHMVVPRLYMELFAVVCIETSHYVAFVKSGSGPDAPWCFFDSMADRKGEQNGYNIPEITCVPELTQWLSEEGARSINETSTNDKVLPEHAKRIFCDAYMCLYQSTDIMMYH", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::.:. * :: * :.*** * *:. *:: ** ::. * :::* : : * : * . . : .**: : :* . ** * **.. **:. . :* : : **..: .: .: * *::: * . * :**:.**.: : **:**:* *** .: *.*:*:*:*. . .:** ..* * *** :*:** : * .* **..:. .* :. :: ** . .: . ** : : * : ** ******:******:***.:*:*:*.:*::* * *:. *.*.*::** ******* :* : ::****.:*:::.:.**:*.********** *: .*:**:*:*:: *. **. ***:*::*.:*: :*: ***:* ** .*::*: *.***:*********::*:: :*:** *::**:::::**:* :** ** ****:*: . : .* : . ** .* . .* * :* .* : **:: . .: * ******:************ *. *:.* ********.* ***:***::: **: ::*. : : : : : *:*::******:***. : :*:", "identical_positions": 241, "similar_positions": 202, "identity": "24.67%" }, { "cls_id": "homologset.agr.RGD:1308347", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q3B7D1-1", "uniprot_id": "UBE2Z_RAT", "id": "Q3B7D1-1", "name": "Ubiquitin-conjugating enzyme E2 Z", "aln": "MAESPTEEAATATAGAGAAGPGASGVAGVVGVSGSGGGFGPPFLPDVWAAAAAAGGAGGPGSGLAPLPGLPPSAAAHGAALLSHWDPTLSSDWDGERTAPQCLLRIKRDIMSIYKEPPPGMFVVPDTVDMTKIHALITGPFDTPYEGGFFLFVFRCPPDYPIHPPRVKLMTTGNNTVRFNPNFYRNGKVCLSILGTWTGPAWSPAQSISSVLISIQSLMTENPYHNEPGFEQERHPGDSKNYNECIRHETIRVAVCDMMEGKCPCPEPLRGVMEKSFLEYYDFYEVACKDRLHLQGQTMQDPFGEKRGHFDYQSLLMRLGLIRQKVLERLHNEN--AEMDSDSSSSGTETDLHGSLRV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UE37-1", "uniprot_id": "UBE2Z_MOUSE", "id": "Q3UE37-1", "name": "Ubiquitin-conjugating enzyme E2 Z", "aln": "MAESPTEEAATATAGAGAAGPGSSGVAGVVGVSGSGGGFGPPFLPDVWAAAAAAGGAGGPGSGLAPLPGLPPSAAAHGAALLSHWDPTLSSDWDGERTAPQCLLRIKRDIMSIYKEPPPGMFVVPDTVDMTKIHALITGPFDTPYEGGFFLFVFRCPPDYPIHPPRVKLMTTGNNTVRFNPNFYRNGKVCLSILGTWTGPAWSPAQSISSVLISIQSLMTENPYHNEPGFEQERHPGDSKNYNECIRHETIRVAVCDMMEGKCPCPEPLRGVMEKSFLEYYDFYEVACKDRLHLQGQTMQDPFGEKRGHFDYQSLLMRLGLIRQKVLERLHNEN--AEMDSDSSSSGTETDLHGSLRV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H832-1", "uniprot_id": "UBE2Z_HUMAN", "id": "Q9H832-1", "name": "Ubiquitin-conjugating enzyme E2 Z", "aln": "MAESPTEEAAT--AGAGAAGPGASSVAGVVGVSGSGGGFGPPFLPDVWAAAAAAGGAGGPGSGLAPLPGLPPSAAAHGAALLSHWDPTLSSDWDGERTAPQCLLRIKRDIMSIYKEPPPGMFVVPDTVDMTKIHALITGPFDTPYEGGFFLFVFRCPPDYPIHPPRVKLMTTGNNTVRFNPNFYRNGKVCLSILGTWTGPAWSPAQSISSVLISIQSLMTENPYHNEPGFEQERHPGDSKNYNECIRHETIRVAVCDMMEGKCPCPEPLRGVMEKSFLEYYDFYEVACKDRLHLQGQTMQDPFGEKRGHFDYQSLLMRLGLIRQKVLERLHNEN--AEMDSDSSSSGTETDLHGSLRV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DG60-1", "uniprot_id": "UBE2Z_DANRE", "id": "Q6DG60-1", "name": "Ubiquitin-conjugating enzyme E2 Z", "aln": "MAHTITPAVES---GLGVLTHAVSSTVPVAVLPSLPPGIG---------------------------SGVPAGAGLLSQIHATSWDPTLSTDWDNEKASQQCILRIKRDIMSIYKEPPPGMFVVPDPHDMTKIHALITGPFDTPYEGGFFLFLFRCPPDYPIHPPRVKLITTGHNTVRFNPNFYRNGKVCLSILGTWTGPAWSPAQSISSVLISIQSLMTENPYHNEPGFEQERHPGDSKNYNECIRHETMRVAVCDMLEGKVSCPEALWSVMEKSFLEYYDFYEGVCKERLHLQGQNMQDPFGEKRGRFDYQGLLTRLRAIQRRLREKCPPEDNDGDSDSDTSSSGTDPDSQGSSQP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.: * . : * *. . *... *. :.. *:* .*:*..*. . : ******:***.*::: **:***********************. ************************:****************:***:****************************************************************************:*******:*** .***.* .************** .**:*******.**********:****.** ** *:::: *: *: .: ***:*****:.* :** : ", "identical_positions": 235, "similar_positions": 54, "identity": "65.64%" }, { "cls_id": "homologset.agr.RGD:1308349", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q6PCX9-1", "uniprot_id": "TRI37_MOUSE", "id": "Q6PCX9-1", "name": "E3 ubiquitin-protein ligase TRIM37", "aln": "MDEQSVESIAEVFRCFICMEKLRDARLCPHCSKLCCFSCIRRWLTEQRAQCPHCRAPLQLRELVNCRWAEEVTQQLDTLQLCSLTKHEENEKDKCENHHEKLSVFCWTCKKCICHQCALWGGMHGGHTFKPLAEIYEQHVTKVNEEVAKLRRRLMELISLVQEVERNVEAVRNAKDERVREIRNAVEMMIARLDTQLKNKLITLMGQKTSLTQETELLESLLQEVEHQLRSCSKSELISKSSEILMMFQQVHRKPMASFVTTPVPPDFTSELVPSYDSATFVLENFSTLRQRADPVYSPPLQVSGLCWRLKVYPDGNGVVRGYYLSVFLELSAGLPETSKYEYRVEMVHQSCNDPTKNIIREFASDFEVGECWGYNRFFRLDLLANEGYLNRQNDTVILRFQVRSPTFFQKCRDQHWYITQLEAAQTGYIQQINNLKERLTIELSRTQKSRDLSPPDNHLSPQNDDSPETRTKKAGSCSDMLLEGGPTCASVRETKEDEDEEEKIQNEDYHHELSDGDLDLDLVGEDEVNHLDGSSSSASSTATSNTEENDIDEETMSGENDVEYNSMELEEGELMEDAAAAGPPGSSHSYVGASSRMSRRTHLCSAATSSLLDIDPLILIHLLDLKDRSSMENLWGLQPRPSASLLQPTASYSRKDKDQRKQQAMWRVPSDLKMLKRLKTQMAEVRCMKTDVKTTLSDIKGSSVASTDMQTNLFCADQAALTTCGPENSGRLQDLGMELLAKSSVAGCYIRNPTNKK-NSPKSAR-AIAGSLSLRRAVDSGENSRSKGDCQVLAEGSSGSSQSGSRHSSPRALTHGIIGDLLPKSEDRQCKALDSDAVVVAVFNGLPTVEKRRKMVTLGTNAKGGRLEGMQMADLESHSEAGEVQPTLPEGASAAPEEGMSSDSDIECDTENEEQEEHTSMGAFNDPFLAQ--PPDEDSHSSFPDGEQIDPENLHFNPDEGGGR------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LE63-1", "uniprot_id": "A0ABK0LE63_RAT", "id": "A0ABK0LE63-1", "name": "E3 ubiquitin-protein ligase TRIM37", "aln": "MDEQSVESIAEVFRCFICMEKLRDARLCPHCSKLCCFSCIRRWLTEQRAQCPHCRAPLQLRELVNCRWAEEVTQQLDTLQLCSLTKHEENEKDKCENHHEKLSVFCWTCKKCICHQCALWGGMHGGHTFKPLAEIYEQHVTKVNEEVAKLRRRLMELISLVQEVERNVEAVRNAKDERVREIRNAVEMMIARLDTQLKNKLITLMGQKTSLTQETELLESLLQEVEHQLRSCSKSELISKSAEILMMFQQVHRKPMASFVTTPVPPDFTSELVPSYDSATFVLENFSTLRQRADPVYSPPLQVSGLCWRLKVYPDGNGVVRGYYLSVFLELSAGLPETSKYEYRVEMVHQSCNDPTKNIIREFASDFEVGECWGYNRFFRLDLLANEGYLNRQNDTVILRFQVRSPTFFQKCRDQHWYITQLEAAQTGYIQQINNLKERLTIELSRTQKSRDLSPPDNHLSPQNDDTPETRAKKAGSCSDMLLEGGPTSASVRETKEDEDEEEKIQNEDYHHELSDGDLDLDLVGEDEVNHLDGSSSSASSTATSNTEENDIDEETMSGENDVEYNSMELEEGELMEDAAAAGPPGSSHSYVGASSRMSRRAHLCSAATSSLLDIDPLILIHLLDLKDRSSMENLWGLQPRPSASLLQPTASYSRKDKDQRKQQAMWRVPSDLKMLKRLKTQMAEVRCMKTDVKTTLADIKGSSVASADLQTNLFCADQAALATCGPENSGRLQDLGMELLAKSSVAGCYIRNPTNKK-NSPKSAR-AIAGSLSLRRAVDSGENSRSKGDCQALSEGSPGSSQSGSRHSSPRALTHGIIGDLLPKSEDRQCKALDSDAVVVAVFNGLPTVEKRRKMVTLGTNVKGGRLEGMQLADLESPSDAGEVQPTLPEGASAAPEEGMSSDSDIECDTENEEQEEHTSMGAFNDPFLAQ--PPDEDSHSSFPDGEQIDPENLHFNTDEGSGRCPRLQLCSQKPSKWPPFSALVHLPPFSSCSYKCLEDRPGCAYPQLTRLLPARARSRPSQAGRNTAA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O94972-1", "uniprot_id": "TRI37_HUMAN", "id": "O94972-1", "name": "E3 ubiquitin-protein ligase TRIM37", "aln": "MDEQSVESIAEVFRCFICMEKLRDARLCPHCSKLCCFSCIRRWLTEQRAQCPHCRAPLQLRELVNCRWAEEVTQQLDTLQLCSLTKHEENEKDKCENHHEKLSVFCWTCKKCICHQCALWGGMHGGHTFKPLAEIYEQHVTKVNEEVAKLRRRLMELISLVQEVERNVEAVRNAKDERVREIRNAVEMMIARLDTQLKNKLITLMGQKTSLTQETELLESLLQEVEHQLRSCSKSELISKSSEILMMFQQVHRKPMASFVTTPVPPDFTSELVPSYDSATFVLENFSTLRQRADPVYSPPLQVSGLCWRLKVYPDGNGVVRGYYLSVFLELSAGLPETSKYEYRVEMVHQSCNDPTKNIIREFASDFEVGECWGYNRFFRLDLLANEGYLNPQNDTVILRFQVRSPTFFQKSRDQHWYITQLEAAQTSYIQQINNLKERLTIELSRTQKSRDLSPPDNHLSPQNDDALETRAKKS-ACSDMLLEGGPTTASVREAKEDEEDEEKIQNEDYHHELSDGDLDLDLVYEDEVNQLDGSSSSASSTATSNTEENDIDEETMSGENDVEYNNMELEEGELMEDAAAAGPAGSSHGYVGSSSRISRRTHLCSAATSSLLDIDPLILIHLLDLKDRSSIENLWGLQPRPPASLLQPTASYSRKDKDQRKQQAMWRVPSDLKMLKRLKTQMAEVRCMKTDVKNTLSEIKSSSAASGDMQTSLFSADQAALAACGTENSGRLQDLGMELLAKSSVANCYIRNSTNKKSNSPKPARSSVAGSLSLRRAVDPGENSRSKGDCQTLSEGSPGSSQSGSRHSSPRALIHGSIGDILPKTEDRQCKALDSDAVVVAVFSGLPAVEKRRKMVTLGANAKGGHLEGLQMTDLENNSETGELQPVLPEGASAAPEEGMSSDSDIECDTENEEQEEHTSVGGFHDSFMVMTQPPDEDTHSSFPDGEQIGPEDLSFNTDENSGR------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*************************************************************************************************************************************************************************************************************************************************:***************************************************************************************************************************************************** *******************.***************.**************************************: ***:**: :*********** *****:****::*********************** *****:***********************************.*****************.****.***:***:***:*****************************:**********.***************************************************.**::**.**.** *:**.**.******::**.********************.*****.**** ****.** ::***********.***********.*:***.*************** ** ***:***:******************.***:***********:*.***:***:*::***. *::**:**.*********************************:*.*:*.*:. *****:**********.**:* **.**..** ", "identical_positions": 884, "similar_positions": 66, "identity": "85.74%" }, { "cls_id": "homologset.agr.RGD:1308350", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LVR6-1", "uniprot_id": "A0ABK0LVR6_RAT", "id": "A0ABK0LVR6-1", "name": "Inverted formin-2", "aln": "MRSWRQGPEWVGRGSRKVLRIWFNKMSVKEGAQRKWAALKEKLGPQDSDPTEANLESAEPELCIRLLQMPSVVNYSGLRKRLESSDGSWMVQFLEQSGLDLLLEALARLSGRGVARIADALLQLTCISCVRAVMNSQQGIEYILSNQGYVRQLSQALDTSNVMVKKQVFELLAALCIYSPEGHALTLDALDHYKMVCSQQYRFSVIMNELSDS-----DNVPYVVTLLSVINALILGPEDLRTRAQLRSEFIGLQLLDILTRLRDLEDADLLIQLEAFEEAKAEDEEELQRVSDGINMNSHQEVFTSLFHKVSCSPASAQLLSVLQGLMHLEPAARSGQLLWEALENLVNRAVLLASDAEACTLEEVVERLLSIKGRP--RPSPLDKAHKSVQTNLGQNQ-GSSSQNTATPTAKVEGRQPVVASPCQHVGSIQSSSMDAAPQ-------LAASPLPTPPLSSSTPVLPPPPPPLPGSGATSPPAPPPPPPLPPPLPGSGTMSPPPPPPP--PLPPPLPGLGAVSPPPPPPPPPLPGSRAVSPPAPP--PSLPHSHP-LPPPPPPPPLPGMCPVPPPPPLPTAGQVPPPPPLPGFSVPSVVGGVEEIIVAQVDHS--LGSAWVPSHRRVNPPTLRMKKLNWQKLPSNVARERNSMWATLSSPCTAEVEPDFSSIEQLFSFPMAKPKEPSAAP--ARKEPKEVTFLDSKKSLNLNIFLKQFKCSNEEVTGMIQAGDTSKFDVEVLKQLLKLLPEKHEIENLRAFTEDRAKLASADQFYILLLDIPCYQLRVECMMLCEGTAIVLDMVRPKAQLVLTACESLLTSQRLPVFCQLILKIGNFLNYGSHTGDADGFKISTLLKLTETKSQQSRVTLLHHVLEEVEKSHPDLLQLSRDLESPSQAAGIHLEIIHSEASANLKKLLEAERKVS--SSIPEVQKQYAERLQASIEASRALDKVFDAIEQKKLELADYLCEDPQKLSLEDTFSTMKTFRDLFTRALKENKDRKEQMAKAEKRKQQLAEEEARRPRDEDGK--------------------------------------------------------------------------------PVRKGPGKQEEVCVIDALLADIRKGFQLRKTARGRGDTEASGRVAPADPPKITEPATASN----PTQGTNQPASEPSSDTTAAGEPQGWDLVDAVTPSPQPTKE--------------------DGGPPSLERRSSWYVDAS-----DFLAPEDILNTQPSEGAWPVTLGDDQALKPLEFSSNKPP----------------------------------------------GVERSHQDATDPEALWGVHRAEADSTSVRPEDATE---------------RGQGTHLPR--PGEDEDEEDTALESALDTSLDRSFSEDAVTDSS--------------------------------------------GSGTLPRVQGRISKGTGKRRKKRPSRRQ---------------------EEFAPDSDDNKAKRLCVIQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q0GNC1-1", "uniprot_id": "INF2_MOUSE", "id": "Q0GNC1-1", "name": "Inverted formin-2", "aln": "-------------------------MSVKEGAQRKWAALKEKLGPQDSDPTEANLESAEPELCIRLLQMPSVVNYSGLRKRLESSDGGWMVQFLEQSGLDLLLEALARLSGRGVARISDALLQLTCISCVRAVMNSQQGIEYILSNQGYVRQLSQALDTSNVMVKKQVFELLAALCIYSPEGHALTLDALDHYKMVCSQQYRFSVIMSELSDS-----DNVPYVVTLLSVINAIILGPEDLRSRAQLRSEFIGLQLLDILTRLRDLEDADLLIQLEAFEEAKAEDEEELQRISDGINMNSHQEVFASLFHKVSCSPASAQLLSVLQGLMHLEPAGRSGQLLWEALENLVNRAVLLASDAQACTLEEVVERLLSIKGRP--RPSPLDKAHKSVQTNSVQNQ-GSSSQNTTTPTTKVEGQQPVVASPCQHVGSIQSSSVDIAPQPVALEQCITALPLPTPPLSSSTPVLPPTPPPLPGPGATSP-LPPPPPPLPPPLPGSGTTSPPPPPPPPPPLPPPLPGSGTISPPPPPPPPPLPGTGAVSPPPPPPLPSLPDSHKTQPPPPPPPPLPGMCPVPPPPPLPRAGQIPPPPPLPGFSVPSMMGGVEEIIVAQVDHS--LGSAWVPSHRRVNPPTLRMKKLNWQKLPSNVARERNSMWATLGSPCTAAVEPDFSSIEQLFSFPTAKPKEPSAAP--ARKEPKEVTFLDSKKSLNLNIFLKQFKCSNEEVTSMIQAGDTSKFDVEVLKQLLKLLPEKHEIENLRAFTEERAKLSNADQFYVLLLDIPCYPLRVECMMLCEGTAIVLDMVRPKAQLVLTACESLLTSQRLPVFCQLILKIGNFLNYGSHTGDADGFKISTLLKLTETKSQQSRVTLLHHVLEEVEKSHPDLLQLSRDLEPPSQAAGINVEIIHSEASANLKKLLEAERKVS--ASIPEVQKQYAERLQASIEASQELDKVFDAIEQKKLELADYLCEDPQQLSLEDTFSTMKTFRDLFTRALKENKDRKEQMAKAERRKQQLAEEEARRPRDEDGK--------------------------------------------------------------------------------PIRKGPGKQEEVCVIDALLADIRKGFQLRKTARGRGDTEASGRVAPTDPPKATEPATASN----PTQGTNHPASEP-LDTTAADEPQGWDLVDAVTPSPQPSKE--------------------EDGPPALERRSSWYVDAI-----DFLDPEDTPDAQPSEGVWPVTLGDGQALNPLEFSSNKPP----------------------------------------------GVKSSHQDATDPEALWGVHQTEADSTSEGPEDEAQ---------------RGQSTHLPRTGPGEDEDGEDTAPESALDTSLDRSFSEDAVTDSS--------------------------------------------GSGTLPRVQGRVSKGTSKRRKKRPSRNQ---------------------EEFVPDSDDIKAKRLCVIQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q27J81-1", "uniprot_id": "INF2_HUMAN", "id": "Q27J81-1", "name": "Inverted formin-2", "aln": "-------------------------MSVKEGAQRKWAALKEKLGPQDSDPTEANLESADPELCIRLLQMPSVVNYSGLRKRLEGSDGGWMVQFLEQSGLDLLLEALARLSGRGVARISDALLQLTCVSCVRAVMNSRQGIEYILSNQGYVRQLSQALDTSNVMVKKQVFELLAALCIYSPEGHVLTLDALDHYKTVCSQQYRFSIVMNELSGS-----DNVPYVVTLLSVINAVILGPEDLRARTQLRNEFIGLQLLDVLARLRDLEDADLLIQLEAFEEAKAEDEEELLRVSGGVDMSSHQEVFASLFHKVSCSPVSAQLLSVLQGLLHLEPTLRSSQLLWEALESLVNRAVLLASDAQECTLEEVVERLLSVKGRP--RPSPLVKAHKSVQANLDQSQRGSSPQNTTTPKPSVEGQQPAAAAACEPVDHAQSESILKVSQ------------PRALEQQASTPPPPPPPPLLPGSSAEPP-----PPPPPPPLPSVGAKALPTAPPP-----PPLPGLGAMAPPAPPLPPPLPGSCEFLPPPPPPLPGLG------CPPPPPPLLPGMGWGPPPP---------PPPLLPCTCSPPVAGGMEEVIVAQVDHG--LGSAWVPSHRRVNPPTLRMKKLNWQKLPSNVAREHNSMWASLSSPDAEAVEPDFSSIERLFSFPAAKPKEPTMVAPRARKEPKEITFLDAKKSLNLNIFLKQFKCSNEEVAAMIRAGDTTKFDVEVLKQLLKLLPEKHEIENLRAFTEERAKLASADHFYLLLLAIPCYQLRIECMLLCEGAAAVLDMVRPKAQLVLAACESLLTSRQLPIFCQLILRIGNFLNYGSHTGDADGFKISTLLKLTETKSQQNRVTLLHHVLEEAEKSHPDLLQLPRDLEQPSQAAGINLEIIRSEASSNLKKLLETERKVS--ASVAEVQEQYTERLQASISAFRALDELFEAIEQKQRELADYLCEDAQQLSLEDTFSTMKAFRDLFLRALKENKDRKEQAAKAERRKQQLAEEEARRPRGEDGK--------------------------------------------------------------------------------PVRKGPGKQEEVCVIDALLADIRKGFQLRKTARGRGDTDGGSKAASMDPPRATEPVATSNPAGDPVGSTRCPASEPGLDATTASESRGWDLVDAVTPGPQPTLEQ-----------------LEEGGPRPLERRSSWYVDAS-----DVLTTEDPQCPQPLEGAWPVTLGDAQALKPLKFSSNQPP----------------------------------------------AAGSSRQDAKDPTSLLGVLQAEADSTSEGLEDAVHS--------------RGARPPAAGPGGDEDEDEEDTAPESALDTSLDKSFSEDAVTDSS--------------------------------------------GSGTLPRARGRASKGTGKRRKKRPSRSQ---------------------EEVPPDSDDNKTKKLCVIQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8JNM1-1", "uniprot_id": "A8JNM1_DROME", "id": "A8JNM1-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------MDSRIGLDYIVENRDYIAKLGAALDTQNATVKKQVFELLSALCAYSPDGYARAIETLEFYKNLKKQRYRFKIVINELELSSAAAHPPLDYQAALLAFINCVIISAATLQERIRIRNEFIGLKVLPLLNNLRLLEAGNVESSASPSPPPSLSSES---------ASSATSPVSGSASTSVTPSPSPLHLQRRLTFCGSLSRYSCAALQLVQNLKKVAQSVGDIIVQLDVFVEQQECDEAQSLQAPDGINLNSHLDVFYAILRQVADTPQEVPFLNILQHLLRIDPKEPLSDIIWDTTERLVHRATLLESH------------EDSVRLLRTPSSQKFACQSCRGSDASSP-----TRKPSQPVGVSAKTTPPPPPPP--------------MAPAAPPPPPPPINGAAPPPPPPPMINGG-----ALPPPPPPPSMQMASRPRTPDPLAAEAVATAILLPQQDTPAPKAKMKTINWGKIPHNKVLGKQNIWSIVASNHQDSPMQDIDWNEMEGLFCLQTASAQGSP-------------KLGRDGSQAAAGSNGCDTLDRKSKKESTEITLLDGKRSLNVNIFLKQFRTSNDDIIQLIRQGAHEEIGAERLRGLLKIMPEVDELDMLKGFNGDKARLGNAEKFLLQLLEVPNYKLRIESMLLKEEFAANVAYLEPCINSMLYAGDDLLNNKTLQEVLYMVVVAGNFLNSGGYAGNAAGVKLSSLQKLTDIRANKPGMNLIHFVALQAEKRNPELLQFTGQLSNLESASKTTSEQINNEINTLDGRIRRIARQIEQPATDVDIKEQMADFLQAAESELSVLQAGMKQVESMRLKMSEFFCDDAATFRLEECFKIFHNFCDKFKQAVKENERRQQQEQQATLRRKQREEQLARRARQIGQAGTPVSDSEHSFLGDAIFDPRASPALSRRHLGSGEISNGFIRLEQDGASPDITPNGSLRRRRSRVLAEEDDLMEFLRSSTGPHHDGHNSRERKAAYGSLDRSWARRARSGSSSRKRPDLLNIDFGMDRERASSPAPLLQQQQQNVQERLQSPLASTAGTPTTAANTPTGSGSAIAQTPSNNEDAKPRISREWRQKIETWLQSNESDEKQNEEYRRKRRLVNANRRSLENETENERKLDPLPEEKILPSTTTATPTNTPTTTNPTNSTNRMDQESGKYQRVYADWKPSRTLEQTDVVANLQAIADAQPHDALRQHRRQRSQEQPSPIALQSIAEEDRRKSLIQKQGERDKSNERLQIYIRRSSSRELQPAKTEEHPLPPKSPKPQVSDDTFASLLSHHKTQNEMQGSSKDVDADNIETPPVSRRVIATPTTTVVTVSMTDKPKAATEEKINPAEQDAPGHFDRHALARRTRRYKRPTDYSSGNEEALTTSTAEAKTSPSKPEPPAPEKSKQKERTINKLEKVGRHISSINQEDVREAIRNLKSPTGTPERPWSPPRDITPSKLKLSASGHHELNDEGFEETQSLVSDTPSHGKGESTNSSCNEGVNETPARQRPMQKQKPTTTSISQMGSRLADRLQQARMKSSGSSGSAASKSQNQIPATQTATVKRSLSASRPLRMPNGQPLASAAPLRSASTVRRSPQEQQVLAGVERSSSRNSLRSSRSSINSGASTQTVVRRLPAVQRAGATVSVDSSPSKRPLAAQNLRPTQGRGVPASRSSSSGSSVGPSVILVRSKMSNTAPKSSIHGSTSFKENQSQSQPQSQSRMSAARSVVLVKNALNQQQQARMSANPSPQQRSTSSSRSVSSFMRPTASSATKRQK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:*: *::**:.*:.*: :*. ****.*. *********:*** ***:*:. ::::*:.** : .*:***.:::.**. * : * .:**:.**.:*:.. *: * ::*.*****::* :* .** ** .:: . .. .. ..*. .: . * * .*: ** . :* * *. :. * : *:.:.: . : : : . :: :. *::. . .. ... :: : :. . * :: ::* : . : .: : :.. . *..* .* . . *: . : *..*** .*..* *** * . **.** . ****** * * .* .. ** *. . :: : .:: *. **. : * * *:.::*::: . .. : * .: .: : * . * .: ::**..*:*:**.*:***:*******: **::: :*: * ::..* *: ***::** .*:: *:.*. ::*:*..*::* : ** :* * **:*.*:* * * : :.* : :* * :.**..: * . ::: ***** *.::*:* *.*:*:* ***: :::: :.*:*.* :.** :*:***:. :*. ..*: * *..* .: :: . *::. :: ::::* :: ***: . *: :. :*. : ::::::*:*. : **: *. :: * * * :*:***: *::* :* *::* *: ***.* . * :.* ..:*. .. .:* . : : .::* * * . : . . * .: ** . :*:*. . * . . * **. : : : **. *:* : * . * * * * : .* ...:.. *: .* :* .: . : .: :. . * . . :. : . :.:: : *.: ::: : .** .. * .* : . .** ***: . * *:... * : : :: ", "identical_positions": 266, "similar_positions": 386, "identity": "13.94%" }, { "cls_id": "homologset.agr.RGD:1308351", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4A8S5-1", "uniprot_id": "D4A8S5_RAT", "id": "D4A8S5-1", "name": "Cell division cycle 7-related protein kinase", "aln": "------------------------------------------------------------MEEPMAFSPLRGCDRCPADDS-------------LKKYEQSVKLSG--------------------IKRDIEELCEAVPQLVSVFKIKDKIGEGTFSSVYLA-------TAQLQEGREE----KIALKHLIPTSHPVRIAAELQCLTVAGGQDNVMGVKYCFRKNDHVVIAMPYLEHESFLDILNSLSFQEVREYMFNLFVALKRIHQFGIVHRDVKPSNFLYNRRLKKYALVDFGLAQGTRDTKIELLKFVQSEAQQEDCSRNKCHGVIG--HKGPLSRPAPKNVDQHITTKTSVKRSYANAQIHIKQGKDGKEGSVGLSVQRSVFGE--------------------RNFNIHSSISHESPAEKLIKQSKTVDIMSRKLATKKMAVSTKAVN-SSMRDSARSCPAALTCDCYGTDRVCSVCLSRRQQVAPRAGTPGFRAPEVLTKCPDQTTAIDMWSAGVIFLSLLSGRYPFYKASDDLTALAQIMTIRGSRETIQAAKAFGKSILCS------KEVPAQDLRTLCERLRGPDSANPKSAVDPPGNTGHHPAASESTDHKAP-HAPASPAQHSEDSLYKRGSGGGRRHPRDRTANPEGWDSVPDDAYDLLDKLLDLNPASRITAEAALVHPFFKDVC----------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z0H0-1", "uniprot_id": "CDC7_MOUSE", "id": "Q9Z0H0-1", "name": "Cell division cycle 7-related protein kinase", "aln": "------------------------------------------------------------MEEPMAFSSLRGSDRCPADDS-------------LKKYEQSVKLSG--------------------IKRDIEELCEAVPQLVNVFKIKDKIGEGTFSSVYLA-------TAQLQEGHEE----KIALKHLIPTSHPMRIAAELQCLTVAGGQDNVMGLKYCFRKNDHVVIAMPYLEHESFLDILNSLSFQEVREYMYNLFVALKRIHQFGIVHRDVKPSNFLYNRRLKKYALVDFGLAQGTRDTKIELLKFVQSEAQQEDCSRNKYHGVVG--HKGLLSRPAPKTVDQQCTPKTSVKRSYT--QVHIKQGKDGKERSVGLSVQRSVFGE--------------------RNFNIHSSISHESPAEKLIKQSKTVDIISRKLATKKTAISTKAMN-SVMRETARSCPAVLTCDCYGSDRVCSVCLSRRQQVAPRAGTPGFRAPEVLTKCPDQTTAIDMWSAGVIFLSLLSGRYPFYKASDDLTALAQIMTIRGSRETIQAAKAFGKSVLCS------KEVPAQDLRALCERLRGLDSTTPRSASGPPGNASYDPAASKNTDHKAS-RVQAAQAQHSEDSLYKRDNDGYWSHPKDCTSNSEGWDSVPDEAYDLLDKLLDLNPASRITAEAALLHAFFKDMCS---------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00311-1", "uniprot_id": "CDC7_HUMAN", "id": "O00311-1", "name": "Cell division cycle 7-related protein kinase", "aln": "----------------------------------------------------MEASLGIQMDEPMAFSPQR--DRFQAEGS-------------LKKNEQNFKLAG--------------------VKKDIEKLYEAVPQLSNVFKIEDKIGEGTFSSVYLA-------TAQLQVGPEE----KIALKHLIPTSHPIRIAAELQCLTVAGGQDNVMGVKYCFRKNDHVVIAMPYLEHESFLDILNSLSFQEVREYMLNLFKALKRIHQFGIVHRDVKPSNFLYNRRLKKYALVDFGLAQGTHDTKIELLKFVQSEAQQERCSQNKSHIITG--NKIPLSGPVPKELDQQSTTKASVKRPYTNAQIQIKQGKDGKEGSVGLSVQRSVFGE--------------------RNFNIHSSISHESPAVKLMKQSKTVDVLSRKLATKKKAISTKVMNSAVMRKTASSCPASLTCDCYATDKVCSICLSRRQQVAPRAGTPGFRAPEVLTKCPNQTTAIDMWSAGVIFLSLLSGRYPFYKASDDLTALAQIMTIRGSRETIQAAKTFGKSILCS------KEVPAQDLRKLCERLRGMDSSTPKLTSDIQGHASHQPAISEKTDHKASCLVQTPPGQYSGNSFKKGDSNSCEHCFDEYNTNLEGWNEVPDEAYDLLDKLLDLNPASRITAEEALLHPFFKDMSL---------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W3Y1-1", "uniprot_id": "CDC7_DROME", "id": "Q9W3Y1-1", "name": "non-specific serine/threonine protein kinase Cdc7", "aln": "MADR---VMCQELATPGSHYRRPK--TGVPSTNVVYANG----GGSWRAAPRQTQRLPRQTVQQYATGTPATGSAGRHSGR--------AFATAGATEEQTVEFNG-AAVMGLPATPRTTKQARNKSEEAINDLLTRIPDIGKLFDVHSRIGNGTFSTVLLG-------TLRRESHLPDSLRRKFAIKHHIPTSHPDRIMKELQCMTKMGGKENVVGIHCCMRYDASAAFVMPFMAHDRFQDFYTRMDVPEIRQYMRNLLVALRHVHKFDVIHRDVKPSNFLYNRRRREFLLVDFGLAQHVNPPAARSSGSAAAIAAANNKNNNNNNNNNSKRPRERESKGDVQQIALDAGLGGAVKRMRLHEESNKMPLKPVNDIAPSDAPEQSVDGSNHVQPQLVQQEQQQLQPQQQQQQQQQQQQSQQQQQPQQQSQQQHPQRQPQLAQMDQTASTPSGSKYNTNRNVSAAAANNAKCVCFANPSVCLNCLMKKEVHASRAGTPGYRPPEVLLKYPDQTTAVDVWAAGVIFLSIMSTVYPFFKAPNDFIALAEIVTIFGDQAIRKTALALDRMITLS------QRSRPLNLRKLCLRFRYRSVFSDAKLLKSYESVDGSCEVCRNCDQYFFNCLCEDSDYLTEP--------------------LDAYECFPPSAYDLLDRLLEINPHKRITAEEALKHPFFTAAEEAEQ----TEQDQLANGTPRKMRRQRYQ--SHRTVAASQE-QVKQQVALDLQQAAINKL-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VJ90-1", "uniprot_id": "CDC7B_DROME", "id": "Q9VJ90-1", "name": "non-specific serine/threonine protein kinase", "aln": "MDKKEVQHHRSQQAMTKSLYAIGMGLLGKSATNMDCANTNLESAGKSSSTNYNRNRFYNERFVPMASGTMPSVSGTNHHSRHQQLLLQQAPKCTADLNEKLVKINRQNANKELSTIQAKDMQSVDKNEEALKELQESIPEINKIFDVHCRIGSGTFSTVLLG-------TLQRERGLVETQRRRFAIKHHNPTNHPERILRELECMYRIGGVENVIGINCCIRYNDNVAFIMPYMTHDRFHDIYRSLNFPEIRDYLRNLLIALRHVHKFNVIHRDVKPSNILYNRRTGKFLLCDFGLAQRIADDGSVVQSSDLSSREVFSILRDLENG---------------RSVTLTDGNS------AQAEAEDYMARRRMRALGGGGSVERAVTGP----------------PSIQKLREQAGGHLTKKDVANQRADTMR-----LLNRLRLVSPNADPNNYVVSTNTS-----------------------KKEMHASRAGTPGYRPPEVLLRYPKQSTAVDVWAAGVIMLSLLSGLHPFFKAPHDCGALAEIINLFGDMPVRKTAFLLDRLILLA------QKVNTLDLRRVCMRFRHADFFLAPEIQRKYQRPDGTTEMCRSCEQPTFNCLCSNSGHNLER--------------------YDGLDIFPAVAYDLLSRLLEVNPQKRITAEEALKHPFFSDQHRITPGIPLHQQQLIMHQQQHIMQHQQHLQRSRETLPSSAARTLKAFVCYPMEITSTASQAAGNI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P06243-1", "uniprot_id": "CDC7_YEAST", "id": "P06243-1", "name": "Cell division control protein 7", "aln": "---------------------------------------------------------------------------------------------MTSKTKNIDDIPP-------------------EIKEEMIQLYHDLPGIENEYKLIDKIGEGTFSSVYKAKDITGKITKKFASHFWNYGSNYVALKKIYVTSSPQRIYNELNLLYIMTGSSRVAPLCDAKRVRDQVIAVLPYYPHEEFRTFYRDLPIKGIKKYIWELLRALKFVHSKGIIHRDIKPTNFLFNLELGRGVLVDFGLAEAQMDYKSMISS-----------------------------------------------------QNDYDNYANTNHDGGYSMRNHEQFCP-------------------CIMRNQYSPNSHNQTPPMVTIQNGKVVHLNNVNGVDLTKGYPKNET-------------------------------RRIKRANRAGTRGFRAPEVLMKCGAQSTKIDIWSVGVILLSLLGRRFPMFQSLDDADSLLELCTIFGWKELRKCAALHGLGFEASGLIWDKPNGYSNGLKEFVYDLLNKECTIGTFPEYSVAFETFGFLQQELHDRMSIEPQLPDPKTNMDAVD-----------AYELKKYQEEIWSDHYWCFQVLEQCFEMDPQKRSSAEDLLKTPFFNELNENTYLLDGESTDE------------------DDVVSSSEADLLDKDVLLISE------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: .: :. : .* :* : . :.: :**.****:* . * : : .*:*: *. * ** **: : * ..* : . * . :*: *: * : : . ::.*: :*: **: :*. .::***:**:*:*:* . . * *****: . . . :: : :. : .. . :: * **** *:*.**** : *:* :*:*:.***:**::. .*:::: .* :* :: .: * : * . . : . . .*: . : . . :: : .:::*.: ::::* .* :** * .**. ", "identical_positions": 77, "similar_positions": 122, "identity": "10.09%" }, { "cls_id": "homologset.agr.RGD:1308352", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M8N8-1", "uniprot_id": "A0ABK0M8N8_RAT", "id": "A0ABK0M8N8-1", "name": "Inhibitor of nuclear factor kappa-B kinase subunit epsilon", "aln": "--MLEKIPWNGASVQDLLG---------LENKKSGEVVAVKVFNSASYRRPPEVQVREFEVLRRLDHENIVKLFAVEETGGS-RQKVLVMEYCSSGSLLSVLEDPENTFGLPEEEFLVVLRCVVAGMNHLRENGIVHRDIKPGNIMRLVGKEGQSIYKLSDFGAARKLDDDEKFVSVYGTEEYLHPDMYERAVLRKPQQKAFGVTVDLWSIGVTLYHAATGSLPFIPFGGPRRNKEIMYRITTEKPAGAISGTQKQENGPLEWSYSLPITCRLSVGLQSQLVPILANILEAEQAKCWGFDQFFAETSDILQRTVIHVFSLPQAVLHHIYIHAHNTIAIFLEAVYEQTNVAPKHQEYFF--EGHPCVLEPSLSAQHIAHTAASSPLTLFSMASDTPKGLAFRDPALDVPKFVPKVDLQADYSTAKGVLGAGYQALWLARVLLDGQALMLRGLHWVLVVLQNTCQQTLEITRTALLFLSSSLGTERLSSGAGMLDIQE------LKEATELRSRLQTFS-EVLSKCSHNVTETQRSLSCLVGELLKSRDQIHEDNRSIQKIQCCLDKMHFIYKQFKKSRMRPGLSYNEEQIHKLDKVNFSHLAKRLLQVFQEECAQTYQVSLVTHGKRMRQVQKAQNHLHLIGHSVATCNSEARGAQESLAKMFDQL--LLDRASKQGAEVSPQPMATHPGPDPKDLVFHMQELCNDMKLLAFDLQDNNRLIERLHRVPPTPEV----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R0T8-1", "uniprot_id": "IKKE_MOUSE", "id": "Q9R0T8-1", "name": "Inhibitor of nuclear factor kappa-B kinase subunit epsilon", "aln": "---MQSTTNYLWHTDDLLGQGATASVYKARNKKSGEVVAVKVFNSASYRRPPEVQVREFEVLRRLNHQNIVKLFAVEETGGS-RQKVLIMEYCSSGSLLSVLEDPENTFGLSEEEFLVVLRCVVAGMNHLRENGIVHRDIKPGNIMRLVGEEGQSIYKLSDFGAARKLDDDEKFVSVYGTEEYLHPDMYERAVLRKPQQKAFGVTVDLWSIGVTLYHAATGSLPFIPFGGPRRNKEIMYRITTEKPAGAISGTQKQENGPLEWSYSLPITCRLSMGLQNQLVPILANILEVEEDKCWGFDQFFAETSDILQRTVIHVFSLPQAVLHHVYIHAHNTIAIFLEAVYEQTNVTPKHQEYLF--EGHPCVLEPSLSAQHIAHTAASSPLTLFSMSSDTPKGLAFRDPALDVPKFVPKVDLQADYSTAKGVLGAGYQALWLARVLLDGQALMLRGLHWVLEVLQDTCQQTLEVTRTALLYLSSSLGTERFSSGAGMPDVQE------RKEATELRTRLQTLS-EILSKCSHNVTETQRSLSCLGEELLKNRDQIHEDNKSIQKIQCCLDKMHFIYKQFKKSRMRPGLSYNEEQIHKLDKVNFSHLAKRLLQVFQEECVQTYQVSLVTHGKRMRQVQRAQNHLHLIGHSVATCNSEARGAQESLNKIFDQL--LLDRASEQGAEVSPQPMAPHPGPDPKDLVFHMQELCNDMKLLAFDLQDNNRLIERLHRVPSAPDV----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14164-1", "uniprot_id": "IKKE_HUMAN", "id": "Q14164-1", "name": "Inhibitor of nuclear factor kappa-B kinase subunit epsilon", "aln": "---MQSTANYLWHTDDLLGQGATASVYKARNKKSGELVAVKVFNTTSYLRPREVQVREFEVLRKLNHQNIVKLFAVEETGGS-RQKVLVMEYCSSGSLLSVLESPENAFGLPEDEFLVVLRCVVAGMNHLRENGIVHRDIKPGNIMRLVGEEGQSIYKLTDFGAARELDDDEKFVSVYGTEEYLHPDMYERAVLRKPQQKAFGVTVDLWSIGVTLYHAATGSLPFIPFGGPRRNKEIMYRITTEKPAGAIAGAQRRENGPLEWSYTLPITCQLSLGLQSQLVPILANILEVEQAKCWGFDQFFAETSDILQRVVVHVFSLSQAVLHHIYIHAHNTIAIFQEAVHKQTSVAPRHQEYLF--EGHLCVLEPSVSAQHIAHTTASSPLTLFSTA--IPKGLAFRDPALDVPKFVPKVDLQADYNTAKGVLGAGYQALRLARALLDGQELMFRGLHWVMEVLQATCRRTLEVARTSLLYLSSSLGTERFSSVAGTPEIQE------LKAAAELRSRLRTLA-EVLSRCSQNITETQESLSSLNRELVKSRDQVHED-RSIQQIQCCLDKMNFIYKQFKKSRMRPGLGYNEEQIHKLDKVNFSHLAKRLLQVFQEECVQKYQASLVTHGKRMRVVHETRNHLRLVGCSVAACNTEAQGVQESLSKLLEELSHQLLQDRAKGAQASPPPIAPYPSPTRKDLLLHMQELCEGMKLLASDLLDNNRIIERLNRVPAPPDV----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B651-1", "uniprot_id": "A0ACD6B651_DANRE", "id": "A0ACD6B651-1", "name": "", "aln": "---MTSTANYLWSQEDILGQGATANVYKARNKKTGELVAVKVFNLVSYNRPYEVQMREFEVLQLLNHVNIVKLFAVEEIISNPKQKILVMEYCSGGSLLNMLEQPEHAFGLPESEFLIVLHCVAHGMNHLRENSVVHRDIKPGNIMRQVGEDGRSVYKLADFGAARELEDDEKFVSIYGTEEYLHPHMYERAVLRIPQQKAYGVSVDLWSIGVTIYHMATGSLPFRPFGGPRKNKQMMHKITTEKPAGTIAGVQKEEDGPIEWRDKLPLSCQLSEGLKTQLVPVLANILLADDEKCWKFPQFFSATNDILNRITIYIFSLQQATTYSIYIQFHNTVSIFFEDVQAQTGIEPAAQQYLF--QGHPLILDPSMKVVNIPHTSSDKPMILISRRLERIIGYPFEEP--ESPPMPGKFDVVADFVFTKTIVKVIHQYLRIAYSLQEYRQFILQGFNSYIEQTSSEVIDVTHRISKVKMKLHSSISTEKTLHVFTQTFAHE------FPDFIDSKKKFPLIEAELQQMCGRGIREFQNILQYLRVTLSKHSETLAND-KSIQKMEVLLSQIVDVHFQYFRDRQTRKLGYNDEQIHKFEKLNLSSYLKKFKSLFKDDCFQKYLDVLNTTDRCSRALYDMQTHLDKFRDTLLQRIQDLKAHEILQNKVLERVVHRAVQQPVKAEVVDGKKKEEH-------MILKMTRLKSEMEAVAWELQKNNNMIESLSVVTPTMPVEKKNPQTNRP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V3Y8-1", "uniprot_id": "Q9V3Y8_DROME", "id": "Q9V3Y8-1", "name": "", "aln": "MSFLRGSVSYVWCTTSVLGKGATGSVFQGVNKITGESVAVKTFNPYSHMRPADVQMREFEALKKVNHENIVKLLAIEEDQEG-RGKVIVMELCTGGSLFNILDDPENSYGLPEHEFLLVLEHLCAGMKHLRDNKLVHRDLKPGNIMKFISEDGQTIYKLTDFGAARELEDNQPFASLYGTEEYLHPDLYERAVLRKSIQRSFTANVDLWSIGVTLYHVATGNLPFRPFGG-RKNRETMHQITTKKASGVISGTQLSENGPIEWSTTLPPHAHLSQGLKTLVTPLLAGLLEENREKTWSFDRFFHEVTLILRKRVIHVFFTNRTSSVEVFLEPDEQIDNFRERIFLQTEVPLEKQILLFNNEHLEKKVTPRTIAKAFPATTTDQPIFLYSND-DNNVQLPQQLDLPKFPVFPPNVSVENDASLAKSACSVGHECKRRVDIFTSMDILIKKGVEHFIEMLVTTITLLLKKTESFDNLLSTVIDYADVVHSMARVTKGDQEIKTLLTALENVKSDFDGAADVISQMHKHFVIDDELNDQWTS---SMHGKKCPCKTRASAQAKYLVERLRDSWQHLLRDRATRTLTYNDEQFHALEKIKVDHNGKRIKALLLDNVNPTVAQIAECLADWYKLAQTVYLKTQILEKDVRDCERKLNGIRDELYHVKSELKLDVDTKTINNNNQLAKIEERN-------RLRVMQQQQQEVMAVMRTNSDIISLLSKLGITNGSLESS---------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .:** ** :** ****.** *: ** :**:****.*: ::* *****:*:** . : *:::** *:.***:.:*:.**:::**.* ***:**. : **:***:* :****:******: :.::*:::***:******:*:*:: *.*:*********.:******* . *::: ..*********:** ***.*** **** *:*:: *::***:*.:*.*:*.* *:**:** .** .:** **:. :.*:**.:* : * * * :** .. **.: .:::* :: :::. .: : * * : ** : * :* : : * . :. *::..*: * * . . . * : :..: * :* . :: . : . :: :*.. : . . * : :. : : :. : : . : : : : . . . :: : : :.:: : :.* * **:**:* ::*::.. *:: :: :: . : : . : . .. . :: ..: : : * . . : : . ::. * . . ", "identical_positions": 178, "similar_positions": 208, "identity": "23.99%" }, { "cls_id": "homologset.agr.RGD:1308353", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "F1LW77-1", "uniprot_id": "F1LW77_RAT", "id": "F1LW77-1", "name": "small monomeric GTPase", "aln": "MASEMESSLEVSFSSSCAVSGASGCLPPARSRIFKIIVIGDSNVGKTCLTYRFCAGRFPDRTEATIGVDFRERAVDIDGERIKIQLWDTAGQERFRKSMVQHYYRNVHAVVFVYDMTNMASFHSLPSWIEECKQHLLANDIPRILVGNKCDLRSAIQVPTDLAQKFADTHSMPLFETSAKNPNDNDHVEAIFMTLAHKLKSHKPLMLSQLPDNRISLKPETKPAVTCWC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35963-1", "uniprot_id": "RB33B_MOUSE", "id": "O35963-1", "name": "Ras-related protein Rab-33B", "aln": "MTSEMESSLEVSFSSSCAVSGASGCLPPARSRIFKIIVIGDSNVGKTCLTYRFCAGRFPDRTEATIGVDFRERAVDIDGERIKIQLWDTAGQERFRKSMVQHYYRNVHAVVFVYDMTNMASFHSLPAWIEECKQHLLANDIPRILVGNKCDLRSAIQVPTDLAQKFADTHSMPLFETSAKNPNDNDHVEAIFMTLAHKLKSHKPLMLSQLPDNRISLKPETKPAVTCWC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H082-1", "uniprot_id": "RB33B_HUMAN", "id": "Q9H082-1", "name": "Ras-related protein Rab-33B", "aln": "MAEEMESSLEASFSSSGAVSGASGFLPPARSRIFKIIVIGDSNVGKTCLTYRFCAGRFPDRTEATIGVDFRERAVEIDGERIKIQLWDTAGQERFRKSMVQHYYRNVHAVVFVYDMTNMASFHSLPSWIEECKQHLLANDIPRILVGNKCDLRSAIQVPTDLAQKFADTHSMPLFETSAKNPNDNDHVEAIFMTLAHKLKSHKPLMLSQPPDNGIILKPEPKPAMTCWC", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:.*******.***** ******* **************************************************:**************************************************:********************************************************************************** *** * ****.***:****", "identical_positions": 217, "similar_positions": 7, "identity": "94.76%" }, { "cls_id": "homologset.agr.RGD:1308354", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q15257-1", "uniprot_id": "PTPA_HUMAN", "id": "Q15257-1", "name": "Serine/threonine-protein phosphatase 2A activator", "aln": "--MAEGERQPPPDSSEEAPPATQ--NFIIPKKEIHTVPDMGKWKRSQAYADYIGFILTLNEGVKGKKLTFEYRVSEMWNEVHEEKEQAAKQSVSCDECIPLPRAGHCAPSEAIEKLVALLNTLDRWIDETPP-----VDQP--SRFGNKAYRTWYAKLDEEAENLVATVVPTHLAAAVPEVAVYLKESVGNSTRIDYGTGHEAAFAAFLCCLCKIGVLR-VDDQIAIVFKVFNRYLEVMRKLQKTYRMEPAGSQGVWGLDDFQFLPFIWGSS---QLIDHPYLEPRHFVDEKAVNENHKDYMFLECILFITEMKTGP-FAEHSNQLWNISA-VPSWSKVNQGLIRMYKAECLEKFPVIQHFKFG-SLLPIHPVTSG---------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P58389-1", "uniprot_id": "PTPA_MOUSE", "id": "P58389-1", "name": "Serine/threonine-protein phosphatase 2A activator", "aln": "--MAEGERQPPPDSSEETPPTTQ--NFIIPKKEIHTVPDMGKWKRSQAYADYIGFILTLNEGVKGKKLTFDYKV-----------------------------------SEAIEKLVALLDTLDRWIDETPP-----VDQP--SRFGNKAYRTWYAKLDQEAENLVATVVPTHLAAAVPEVAVYLKEAVGNSTRIDYGTGHEAAFAAFLCCLCKIGVLR-VDDQVAIVFKVFDRYLEVMRKLQKTYRMEPAGSQGVWGLDDFQFLPFIWGSS---QLIDHPHLEPRHFVDEKAVSENHKDYMFLQCILFITEMKTGP-FAEHSNQLWNISA-VPSWSKVNQGLIRMYKAECLEKFPVIQHFKFG-SLLPIHPVTSG---------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LHB2-1", "uniprot_id": "A0ABK0LHB2_RAT", "id": "A0ABK0LHB2-1", "name": "Serine/threonine-protein phosphatase 2A activator", "aln": "--MAEGERQPPPDSSEETPSATP--TFIIPKKEIHTVPDMGKWKRSQAYADYIGFILTLNEGVKGKKLTFDYKV-----------------------------------SEAIEKLVALLDTLDRWIDETPP-----VDQP--SRFGNKAYRTWYAKLDQEAENLVATVIPTNLAAAVPEVAVYLKEAVGNSTRIDYGTGHEAAFAAFLCCLCKIGVLR-VDDQVAIVFKVFDRYLEVMRKLQKTYRMEPAGSQGVWGLDDFQFLPFIWGSS---QLIDHPHLEPRHFVDEKAVSENHKDYMFLQCILFITEMKTGP-FAEHSNQLWNISA-VPSWSKVNQGLIRMYKAECLEKFPVIQHFKFG-SLLPIHPVTSG---------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2CF49-1", "uniprot_id": "A2CF49_DANRE", "id": "A2CF49-1", "name": "Serine/threonine-protein phosphatase 2A activator", "aln": "--MAETEQASGSSHEDDKPPSSVGFNFMVPKKEISMVPDMGKWKRSQAYADYIGFILTLNEGVKGKKLTCEYQV-----------------------------------SETVEKLLALLGTLDQWIDETPP-----VDQP--SRFGNKAFRTWYAKLDQEAEALVAGVLPAERQDAAPEIAVYLKESVGNSTRIDYGTGHEAAFAAFLCCLCKVGALR-MEDQLAIIFNVFDKYLRVMRKLQKTYRMEPAGSQGVWGLDDFQFLPFIWGSS---QLIDHPTLEPRHFVEEKVVNEYHQDYMFLECIKFINEMKTGP-FAEHSNQLWNISA-VPSWSKVNQGLIRMYKAECLEKFPVIQHFKFG-SLLSIQPVKP----------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P40454-1", "uniprot_id": "PTPA1_YEAST", "id": "P40454-1", "name": "Serine/threonine-protein phosphatase 2A activator 1", "aln": "--------------MSLDRVDWPHATFSTPVKRIFDTQTTLDFQSSLAIHRIKYHLHKYTTLISHCSDPDPHATASS--------------------------------IAMVNGLMGVLDKLAHLIDETPP-----LPGP--RRYGNLACREWHHKLDERLPQWLQEMLPSEYHEVVPELQYYLGNSFGSSTRLDYGTGHELSFMATVAALDMLGMFPHMRGAD--VFLLFNKYYTIMRRLILTYTLEPAGSHGVWGLDDHFHLVYILGSSQWQLLDAQAPLQPREILDKSLVREYKDTNFYCQGINFINEVKMGP-FEEHSPILYDIAVTVPRWSKVCKGLLKMYSVEVLKKFPVVQHFWFGTGFFPWVNIQNGTDLPVFE--EKEEESIEQANAGSPGREQTSTRFPTSTSMPPPGVPPSGNNINYLLSHQNQSHRNQTSFSRDRLRR------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q12461-1", "uniprot_id": "PTPA2_YEAST", "id": "Q12461-1", "name": "Serine/threonine-protein phosphatase 2A activator 2", "aln": "---------------------------MLPEKRLLTPDDMKLWEESPTRAHFTKFIIDLAESVKGHENSQYKEPIS----------------------------------ESINSMMNLLSQIKDITQKHPV-----IKDADSSRFGKVEFRDFYDEVSRNSRKILRSEFPSLTDEQLEQLSIYLDESWGNKRRIDYGSGHELNFMCLLYGLYSYGIFNLSNDSTNLVLKVFIEYLKIMRILETKYWLEPAGSHGVWGLDDYHFLPFLFG---AFQLTTHKHLKPISIHNNELVEMFAHRYLYFGCIAFINKVKSSASLRWHSPMLDDISG-VKTWSKVAEGMIKMYKAEVLSKLPIMQHFYFS-EFLPCPDGVSPPRGHIHDGTDKDDECNFEGHVHTTWGDCCGIKLPSAIAAT----------------EMNKKHHKPIPFD------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VXN8-1", "uniprot_id": "Q9VXN8_DROME", "id": "Q9VXN8-1", "name": "Serine/threonine-protein phosphatase 2A activator", "aln": "MSNKLGYDVTDPTVQLLRASAFMQN---GPVKQVRSLEDLDRWVRSQAYYDIIAYISNTSKAIQGHRLTQTFPVT-----------------------------------EQMRRLSEIFDGLDHLIVEHTPKIEDSYLALPFGQVRSKAYRTWMREMYQHVFSKLDEAINVN-CKHINELGQYLRRSFGNGNTLDFGPANELMFLFFLCGLFRAGIL-LAKDTVAAALMLFNRYVNVVRRLISTYGLTIAKDP-ACTIEDYYFLPYLWGAA---QLSVDSPFSPMQCEQGKIMDNYRQDFMMLEIIDHLQKTRSGP-LSRVALQLWSILS-IPTWPQVYRGLERNYIDHVLSSFGTVEQAIFC-ELMSFEAVVPIMPLQRAHLG-THLIVDEKENEDELEQKYGENRWSLSPPVSRYVSMEPESFLG-FQASKTHNKSKESEDERLWMMRQLVDENDPNSDMFFPDREVKGRDSLTSFAN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VNG7-1", "uniprot_id": "Q9VNG7_DROME", "id": "Q9VNG7-1", "name": "Serine/threonine-protein phosphatase 2A activator", "aln": "-------MEPQSEVNPKRVAAFFRRSNIGPVCRVQSSSDMEAWLASRAYFTLITYLNDVSAEIQGIRNTDLFPIS-----------------------------------KNIKRLTTIFEQLDSMIVANSP---APLVLGANMDSRTKSYRRWAHGMLRDIYKIVEKAVPSSKCRHVNELGVYLSGSFGSSAKIEYGTGHELSFLFFVCALFKAEILDKEQDLAASALVLFDRYLHFVRRLQVTYSVNSSNWHGGYSLDKFQFVPFVWGFA---QLCHEAPFSPKKMLDEDTIAKYRDAYMLINCVGHMATTNVGT-FARHSSQLWSLAA-LSSWTKIHRSLMFMYMEDILMDIDNLNALRFG-ELMSFEEDKSGRHLGSARMG-VKSPLRRQMAEDPDDQDQDQDLTSRSGTPSISRSEQNDSARKKAKVEETSSDCMSNSGLSLGSECTSLSGVSVHLPTWLDDCTATSKNAF-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VQQ0-1", "uniprot_id": "PTPA_DROME", "id": "Q9VQQ0-1", "name": "Serine/threonine-protein phosphatase 2A activator", "aln": "-------MASGINQAAGKLPAIAKK--------VQNLGDMGVWQKSRAFHDLIGYINGTSSAIQGIKTTDEIFES-----------------------------------EMLKKLLRLFDALEKLVEQNPP-------LEQPQRFGNKAYRDWAQAMRELLPELLEQLLPDDKKRYQVELGQYLTESFGNATRIDYGTGHELSFLFFLCSLFKAEIL-QERDIVSAALRLFNRYLELARQLQRTYNMEPAGSQGVWSLDDFQFVPFIWGSA---QLAVKSPFDPSKFVDEAIITEYKDHFMFISCIDYICKVKTGH-FGEHSNQLWSITD-VPTWAKINAGLVKMYQKEILSKFPVIQHVYFG-ELMTFEPVSSGTTLSNARLGHVAPPPSKRICIGTPNLVPPVPVATAPPPPAESLSIEQNVGDSSSESSDNSVVLRPSTSSSSLVAAAEGSGDKPSKE-------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * : .: :. . :. : :: : . . * : : . : . :: ** : *. :::*..:* * : * : . : :* .* . * * .* : : ::.. .: :: * * . :.* : : . : : .: . . : : * .: : *.:: .: * . * .: :: * ::. ", "identical_positions": 22, "similar_positions": 79, "identity": "4.57%" }, { "cls_id": "homologset.agr.RGD:1308355", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZWD6-1", "uniprot_id": "D3ZWD6_RAT", "id": "D3ZWD6-1", "name": "", "aln": "MFTVAFFGLSLMAWHSGVTAQEKVNQRVTRAVTPGAVACQLSDWSEWTDCFPCQNEKYRYRSLLQPSKFGGTICSGDIWDKANCDSPTPCLRQAQCGQDFQCRETGRCLKRHLVCNGDQDCLDGSDEDNCDDARVIEDDCRQYEPIPGSERAALGYNILTQEEGQSVYDAKYYGGQCETVYNGDWRRLQYDPTCERLYYGEDEKYFRKPYNFLKYHFEALADTLISSEFYDDANDLFSKIQRDKSQSNSVTFGISPAKSPITLDASVSWSDESSFMKELSKYNEKKYSFMRVSTKVQTAHFKMRRHNIVLDEGMMESLMELPEQFNYGMYSKFINDYGTHYITSGTMGGIYEYVLVLDKEKMRIHGITVEDVKKCIGGGVGLQFGEKIIGEGDLSGESCVMTGDGNQDKRKKDLAVEDIISRVQGGSSRWSTGLAHNSSAITYRSWGRSLKYNPVVIDFEMQPIYQLLQHTNLGPLETKRRNLRRALDQYLMEFNACRCGPCFNNGVPILEGTSCSCQCSMGRQGPACESMVLEAMEGAKADGRWSCWSSWSECRGGSRERRRQCNNPAPQNGGAPCLGKSLQTQAC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K182-1", "uniprot_id": "CO8A_MOUSE", "id": "Q8K182-1", "name": "Complement component C8 alpha chain", "aln": "MFVVAFFGLSLVAWHPGVTAQEKVNQRVTRAVTPQAVSCQLSDWYKWTDCFPCQDKKYRYRSLLQPSKFGGTICSGDIWDEASCDSPTPCLRQAQCGQDFQCRETGRCLKRHLVCNGDNDCLDGSDESDCEDVRVTEDDCHQYEPIPGSERAALGYNILTQEEAQSVYDAKYYGGQCETVYNGDWRKLRYDPTCERLYYGEDEKYFRKPYNFLKYHFEALADTSISSEFYDDANDLFFHIKNGKSHSAGVTVGVAPVKSPVSIEVTGSGSKASSFLNKLNKYNEKRYGFMRVSTKIQTAQFKMRRNNIVLDEGMLQSLMELPEQFNYGMYAKFINDYGTHYITSGTMGGIYEYVMVLDKEKMKTEGTTVDEVQKCIGGGIGIGIKDSTIEGVGISGEFCENSGDGDRDIRKKITGVEDIISRVQGGSSVWGSVLTHNSSAITYQSWGRSLKYNPVVIDFEMQPIYQLLRHTNLGPLETKRQNLRRALDQYLMEFNACRCGPCFNNGEPILDGTNCRCQCSMGRQGLACERTVIEGLKDFKAAGHWSCWSSWSECRGGSQERRRQCNNPPPKNGGTPCLGRNLQTQAC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P07357-1", "uniprot_id": "CO8A_HUMAN", "id": "P07357-1", "name": "Complement component C8 alpha chain", "aln": "MFAVVFFILSLMTCQPGVTAQEKVNQRVRRAATPAAVTCQLSNWSEWTDCFPCQDKKYRHRSLLQPNKFGGTICSGDIWDQASCSSSTTCVRQAQCGQDFQCKETGRCLKRHLVCNGDQDCLDGSDEDDCEDVRAIDEDCSQYEPIPGSQKAALGYNILTQEDAQSVYDASYYGGQCETVYNGEWRELRYDSTCERLYYGDDEKYFRKPYNFLKYHFEALADTGISSEFYDNANDLLSKVKKDKSDSFGVTIGIGPAGSPLLVGVGVSHSQDTSFLNELNKYNEKKFIFTRIFTKVQTAHFKMRKDDIMLDEGMLQSLMELPDQYNYGMYAKFINDYGTHYITSGSMGGIYEYILVIDKAKMESLGITSRDITTCFGGSLGIQYEDKINVGGGLSGDHCKKFGGGKTERARKAMAVEDIISRVRGGSSGWSGGLAQNRSTITYRSWGRSLKYNPVVIDFEMQPIHEVLRHTSLGPLEAKRQNLRRALDQYLMEFNACRCGPCFNNGVPILEGTSCRCQCRLGSLGAACEQTQTEG---AKADGSWSCWSSWSVCRAGIQERRRECDNPAPQNGGASCPGRKVQTQAC", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.*.** ***:: :.************ **.** **:****:* :********::***:******.*************:*.*.*.*.*:***********:***************:********.:*:*.*. ::** ********::***********:.******.************:**.*:**.********:********************** *******:****: :::..**.* .**.*:.*. **: : . * *. :**:::*.*****:: * *: **:***:****:.:*:*****::******:*:*****:**************:*******::*:** **. * * :: .*:**.:*: :. .:**: * *.*. : :* .********:**** *. *::* *:***:********************:::*:**.*****:**:************************* ***:**.* *** :* * *** *. ** * ******** **.* :****:*:**.*:***:.* *:.:*****", "identical_positions": 395, "similar_positions": 125, "identity": "67.29%" }, { "cls_id": "homologset.agr.RGD:1308356", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8C7U1-1", "uniprot_id": "N4BP3_MOUSE", "id": "Q8C7U1-1", "name": "NEDD4-binding protein 3", "aln": "MATTSGPAGIAMGSVGSLLERQDFSPEELRAALAGSRGSRQPDGLLRKGLGQREFFSYLHLPKKDGK---TTKRAPRNEP-DYATLYYREHPRAGDFSKTSLPERGRFDKCRIRPSVFKPPVGSGKGFLSMQSLAAHKGQKLWRSNGSLHTLACHPPLSPGPRASQARAQLLHALSLDEGGPEP--SLSDSSSGGSFGRSPGTGPSPFSSSLGHINHLGGSLDRAPRSPKESGPLAVLSCLPEPPPPYEFSCPTTEEV-AVLPEAREELKRDLGDQDVSNSFTQVLEERQRLWLSELKRLYVERLHEVAQKAERSERNLQLQLFMAQQEQRRLRKELRAQQGLAPEPRTSGSSMEADPNARPEEEARWEVCQKTAEISLLKQQLREAQAELAQKLAEIFSLKTQLRGSRAQAQAQDAELARLREAVHSLQEQAPREEAPGSCETDDCKSRGLLGEAGGSEAREGAEQLRAELLQERLRGQEQALRFEQERQTWQEEKERVLRYQREIQGSYMDMYRRNQALEHELRLLREPPTSWSPRLESSKI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3LUD3-1", "uniprot_id": "N4BP3_RAT", "id": "Q3LUD3-1", "name": "Nedd4 binding protein 3", "aln": "MATASGPAGIAMGSVGSLLERQDFSPEELRAALAGSRGSRQPDGLLRKGLGQREFFSYLHLPKKDGK---TAKRAPRNEP-DYTTLYYREHPRAGDFSKTSLPERGRFDKCRIRPSVFKPPVSTGKGFLSMQSLAAHKGQKLWRSNGSLHTLACHPPLSPGPRASQARAQLLHALSLDEGGPEP--SLSDSSSGGSFGRSPGTGPSPFSSSLGHINHLGGSLDRASRSPKESGPLAVLSCLPEPPPPYEFSCPTTEEV-AVLPDTCEELKRDLGDQDVSNPFTQVLEERQRLWLSELKRLYVDRLHEVAQKAERSERNLQLQLFMAQQEQRRLRKELRAQQGLAPEPRTSGPPMEADPNARPEEEARWEVCQKTAEISLLKQQLREAQAELAQKLAEIFSLKTQLRGSRAQAQAQDAELARLREAVRSLQEQAPREEAPGSCETDDCKSRGLLGEAGGNEAREGAEQLRAELLQERLRGQEQALRFEQERQTWQEEKERVLRYQREIQGSYMDMYRRNQALEQELRVLREPPTSWSPRLESSKI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O15049-1", "uniprot_id": "N4BP3_HUMAN", "id": "O15049-1", "name": "NEDD4-binding protein 3", "aln": "MATAPGPAGIAMGSVGSLLERQDFSPEELRAALAGSRGSRQPDGLLRKGLGQREFLSYLHLPKKDSKSTKNTKRAPRNEPADYATLYYREHSRAGDFSKTSLPERGRFDKCRIRPSVFKPTAGNGKGFLSMQSLASHKGQKLWRSNGSLHTLACHPPLSPGPRASQARAQLLHALSLDEGGPEPEPSLSDSSSGGSFGRSPGTGPSPFSSSLGHLNHLGGSLDRASQGPKEAGPPAVLSCLPEPPPPYEFSCSSAEEMGAVLPETCEELKRGLGDEDGSNPFTQVLEERQRLWLAELKRLYVERLHEVTQKAERSERNLQLQLFMAQQEQRRLRKELRAQQGLAPEPRAPGTLPEADPSARPEEEARWEVCQKTAEISLLKQQLREAQAELAQKLAEIFSLKTQLRGSRAQAQAQDAELVRLREAVRSLQEQAPREEAPGSCETDDCKSRGLLGEAGGSEARDSAEQLRAELLQERLRGQEQALRFEQERRTWQEEKERVLRYQREIQGGYMDMYRRNQALEQELRALREPPTPWSPRLESSKI", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:.**************************************************:*********.* .:******** **:*******.****************************....***********:************************************************ ****************************:**********.:.***:** *****************.::**: ****:: *****.***:* **.*************:*******:*****:***************************************:.*. ****.************************************************************.******:*******************************.***:.**************************:******************.************:*** ******.**********", "identical_positions": 488, "similar_positions": 43, "identity": "89.71%" }, { "cls_id": "homologset.agr.RGD:1308357", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZJT6-1", "uniprot_id": "D3ZJT6_RAT", "id": "D3ZJT6-1", "name": "", "aln": "------------------------------------------------MEYFMVPTQKVPSLQHFRKTEKEVIGGLCSLANIPLTPETQRDQERRIRREIANSNERRRMQSINAGFQSLKTLIPHTDGEKLSKAAILQQTAEYIFSLEQEKTRLLQQNTQLKRFIQELSGSSP---------------------------KRRRAED-----------KDEGIGSPD---------------IWEDEKAEDLRREMIELRQQLDKERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQQQQEQVRLLHQEKLEREQQHLRTQLLPPP--------------------------------------APTHHPTVIVPAPAPPSSHHINVVTMGPSSVINSVS-------------------------------------------------TSRQNLDTIVQAIQHIEG--------------------------------------------------TQDRQELEEEQRRAVIVKSVRSCPEAHTSDTASDSEASDSDAMDQSREEPLGDGELP-------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q01664-1", "uniprot_id": "TFAP4_HUMAN", "id": "Q01664-1", "name": "Transcription factor AP-4", "aln": "------------------------------------------------MEYFMVPTQKVPSLQHFRKTEKEVIGGLCSLANIPLTPETQRDQERRIRREIANSNERRRMQSINAGFQSLKTLIPHTDGEKLSKAAILQQTAEYIFSLEQEKTRLLQQNTQLKRFIQELSGSSP---------------------------KRRRAED-----------KDEGIGSPD---------------IWEDEKAEDLRREMIELRQQLDKERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQQQQEQVRLLHQEKLEREQQQLRTQLLPPP--------------------------------------APTHHPTVIVPAPPPPPSHHINVVTMGPSSVINSVS-------------------------------------------------TSRQNLDTIVQAIQHIEG--------------------------------------------------TQEKQELEEEQRRAVIVKPVRSCPEAPTSDTASDSEASDSDAMDQSREEPSGDGELP-------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V406-1", "uniprot_id": "Q9V406_DROME", "id": "Q9V406-1", "name": "", "aln": "MSAVPVAIKTEEVILEHAEYNSAEELDEELQLQLEDSGGENYHIEFASESAHQGSQRRQSSMSGTNTSKGGGGGGSGALSDGDGSGKPLVDSEKRMRREIANSNERRRMQSINAGFQSLRSLLPRHEGEKLSKAAILQQTFQYIVELENQKTQLLTQNSELKRQVGEHEAGGSGDGGGTNSGGNYNDSNASGGNSTAVAIKKRKLTDNVINIQAISDSSDEGLGSMSPEPMTLLTAGGAAATKLSNAATLLAAKELHESKKQLEKERSLRRLLEDELQMIKRQLYSVATAPPGTAVAAASGGSSGAYIPREVIEHTDNFVRSEDLEELGGTVSYVEIDEMTGQQQVVVCSSIEELEADAAAEIITEDQVHEEVILSSNSSTESENEVNVNAIAKAYAEGCTSSAAMLQPILQAAIKATPKVEVERIHEKIVKVKTEKHDLPSMQTAPHYQHSHRQNLETIVQAIRHLEGDHLFADGSGGQEKFGQQQNLQQHHHQMSGVHHQQLQHHRLAQDAPLALTTTGKQHAALAELRPFLQLKSGGNKQVIITAKTAKDSGGLVSTSTSSTAVTPTAIFKVQTTGGHGNGSHLPAGSSTGTIITGSNGSGGAQQLTITTSLKQCRPGVIVAKQLPSS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . :: .*:. ..:: ** :*:: : :. *.*:*:***********************::*:*: :************* :**..**::**:** **::*** : * ..... *:*: * .***:** . .: : :*: * ::**:****:* :**:::: :: ::*. . * . .. : :* :*: :: :*:: * .*. .:: . ... ..:.:** ::. : . ...* : ****:******:*:** * .:: * * : :*. . *:.**.** . * : ..: * . :: ", "identical_positions": 112, "similar_positions": 121, "identity": "17.75%" }, { "cls_id": "homologset.agr.RGD:1308359", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4A2E7-1", "uniprot_id": "D4A2E7_RAT", "id": "D4A2E7-1", "name": "", "aln": "MG--PEMRLTRICCCCCLLYQLGFLSHGTISGMQLTPDLEEWEVVFPALWRRESLNATGLSTGSADPGSGRSAGGGS--RGQPSGSSREVRSVARAPLEEAAGGQSEPWFAARPLQPGAEDEEELESQELPRGSSGDTSLPSGAPAPWQPSPSPQPPSSPPPAQQEEPSTEEVLLRIPALSRDLYLLLRRDGRFLAQRFAVEQWPKPGPDPTRATVDPRPPMPSDASCFYTGTVLRHPGSLASFSTCGGGLMGFIQLNEDFIFIEPFNDTMAIIGHPHRLYRQKRSSEERVTEKSAAHRHHCGVISDKGRPRSKKLAENRREKRYSYKLPQDYNIETVVVADPAMVSYHGAD--AARRFILTILN-MVFNLFQHKSLGVQVNLRVIKLILLHETPADLYIGHHGEKMLESFCKWQHEEFGRKNDIHLEMSTSWGEDVASVDAAILITRKDFCVHKDEPCDTVGIAYLNGMCSEKRK--CIIAEDNGLNLAFTIAHEMGHNMGINHDN-DHPSCADGLHIMSGEWIKGQNLGDVS-------WSRCSKEDLERFLRSKASSCLLHTDPQSLSSVLVPSKLPGMAYTADEQCQILFGPLASFCQEMQHVICTGLWCRVEGDTECRTKLDPPMDGTDCDPGKWCKAGECTRRTPAPEHLAGEWSTWSSCSRSCGSGVSSRERKCPGLGSEARDCNGPRKQYRICENPPCPAGLPGFRDWQCQAYSVRTSYPKHALQWQAVFDEEKPCALFCSPVGKEQPVLLSEKVLDGTSCGYQGLDVCANGRCQKAGCDGLLGSLAREDHCGVCNGNGKSCKVIKGDFNHTRGAGYVEVLVIPAGARRIKVVEEKPAHSYLALRDASKQSINSDWKIEHSGAFSLAGTTVHYIRRGLWEKISAKGPTTTPLHLLVLLFQDQNYGLHYEYTVPSDPLPDNQSSKESGPLFMWTHAGWGDCNATCGGGERKTTVSCTKIMNKNISLVDNKKCKDLTKPEPQIRKCNEQPCQTRWMMTEWTTCSRTCGKGVQSRQVACTRQLENGTLIRAWERDCIGPKPATMQRCEGQDCMTVWEAGVWSECSVKCGKGVRHRTVRCTNPRKKCVLSTRPREVEDCEDYSKCYVWRVGDWSKCSITCGKGMQSRVIQCMHKITGRHGNECFSSEKPAAYRPCHLQPCNEKINVNTITSPRLAALTFKCLGDQWPVYCRVIREKNLCQDMRWYQRCCETCRDFYAQKLRQKS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P59509-1", "uniprot_id": "ATS19_MOUSE", "id": "P59509-1", "name": "A disintegrin and metalloproteinase with thrombospondin motifs 19", "aln": "MG--PEMRLTRICCCCCLLYQLGFLSHGTTSGLQLTPDLEEWEVVFPALWRRESLNATGLSGGSSDPGSGRSSGGGG--RGQASGSSREVRSVARAPQEEATRGQSEPWFGS-PLEPGAEDEEELESQELPRGSSGDTALSSGTPASWQPPLPPQRPSSPPPAQQEEPSAEEVLLRIPALSRDLYLLLRRDGRFLAQRFAVEQWPKPGPDPTRATADPGSSLLPDASCFYTGTVLRHPGSLASFSTCGGGLMGFIQLNEDFLFIEPFNDTMAIIGHPHRLYRQKRSTEEKVTENSAVHRHHCGVISDKGRPRSKKIADNRREKRYSYKLSQEYNIETVVVADPAMVSYHGAD--AARRFILTILN-MVFNLFQHKSLGVQVNLRVLKLILLHETPADLYIGHHGEKMLESFCKWQHEEFGRRNDVHLEMSTSWGEDIAAVDAAILITRKDFCVHKDEPCDTVGIAYLNGMCSEKRK--CIIAEDNGLNLAFTIAHEMGHNMGINHDN-DHPSCADGLHIMSGEWIKGQNLGDVS-------WSRCSKEDLERFLRSKASSCLLHTDPQSLSSVLVPSKLPGMAYTADEQCQILFGPLASFCQEMQHVICTGLWCKVEGEAECRTKLDPPMDGTDCDPGKWCKAGECTRRTPAPEHLAGEWSPWSSCSRSCSSGVSSRERKCPGLGSEARDCNGPRKQYRICENPPCPAGLPGFRDWQCQAYSVRTSYPKHALQWQAVFDEEKPCALFCSPVGKEQPVLLSEKVMDGTSCGYQGLDICANGRCQKAGCDGLLGSLAREDHCGVCNGNGKSCKVIKGDFNHTRGAGYVEVLVIPAGARRIKVVEEKPAHSFLALRDASKQSINSDWKIEHSGAFSLAGTTVHYLRRGLWEKISAKGPTTTPLHLLVLLFQDQNYGLHYEYTVPSDPLPDNQSSKEPGPLFMWTHAGWGDCNATCGGGERKTMVSCTKIMSKNISLVDNKKCKDLTKPEPQIRKCNEQPCQTRWMMTEWTTCSRTCGKGVQSRQVACTQQLENGTLIRAWERDCLGPKPATVQRCEGQDCMTVWEAGVWSECSVKCGKGVRHRTVRCTNPRKKCVLSTRPREAEDCEDYSKCYVWRVGDWSKCSITCGKGMQSRVIQCMHKITGRHGNECFSSEKPAAYRPCHLQPCNEKINVNTITSPRLAALTFKCLGDQWPVYCRVIREKNLCQDMRWYQRCCETCRDFYAQKLQQKS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TE59-1", "uniprot_id": "ATS19_HUMAN", "id": "Q8TE59-1", "name": "A disintegrin and metalloproteinase with thrombospondin motifs 19", "aln": "MGKNREMRLTHICCCC-LLYQLGFLSNGIVSELQFAPDREEWEVVFPALWRREPVDPAGGSGGSADPGWVRGVGGGGSARAQAAGSSREVRSVAPVPLEEPVEGRSESRLRPPPPSEGEEDEE-LESQELPRGSSGAAALSPGAPASWQPPPPPQPPPSPPPAQHAEPDGDEVLLRIPAFSRDLYLLLRRDGRFLAPRFAVEQRPNPGPGPTGAASAPQPPAPPDAGCFYTGAVLRHPGSLASFSTCGGGLMGFIQLNEDFIFIEPLNDTMAITGHPHRVYRQKRSMEEKVTEKSALHSHYCGIISDKGRPRSRKIAESGRGKRYSYKLPQEYNIETVVVADPAMVSYHGAD--AARRFILTILN-MVFNLFQHKSLSVQVNLRVIKLILLHETPPELYIGHHGEKMLESFCKWQHEEFGKKNDIHLEMSTNWGEDMTSVDAAILITRKDFCVHKDEPCDTVGIAYLSGMCSEKRK--CIIAEDNGLNLAFTIAHEMGHNMGINHDN-DHPSCADGLHIMSGEWIKGQNLGDVS-------WSRCSKEDLERFLRSKASNCLLQTNPQSVNSVMVPSKLPGMTYTADEQCQILFGPLASFCQEMQHVICTGLWCKVEGEKECRTKLDPPMDGTDCDLGKWCKAGECTSRTSAPEHLAGEWSLWSPCSRTCSAGISSRERKCPGLDSEARDCNGPRKQYRICENPPCPAGLPGFRDWQCQAYSVRTSSPKHILQWQAVLDEEKPCALFCSPVGKEQPILLSEKVMDGTSCGYQGLDICANGRCQKVGCDGLLGSLAREDHCGVCNGNGKSCKIIKGDFNHTRGAGYVEVLVIPAGARRIKVVEEKPAHSYLALRDAGKQSINSDWKIEHSGAFNLAGTTVHYVRRGLWEKISAKGPTTAPLHLLVLLFQDQNYGLHYEYTIPSDPLPENQSSKAPEPLFMWTHTSWEDCDATCGGGERKTTVSCTKIMSKNISIVDNEKCKYLTKPEPQIRKCNEQPCQTRWMMTEWTPCSRTCGKGMQSRQVACTQQLSNGTLIRARERDCIGPKPASAQRCEGQDCMTVWEAGVWSECSVKCGKGIRHRTVRCTNPRKKCVLSTRPREAEDCEDYSKCYVWRMGDWSKCSITCGKGMQSRVIQCMHKITGRHGNECFSSEKPAAYRPCHLQPCNEKINVNTITSPRLAALTFKCLGDQWPVYCRVIREKNLCQDMRWYQRCCETCRDFYAQKLQQKS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B7YZP6-1", "uniprot_id": "B7YZP6_DROME", "id": "B7YZP6-1", "name": "", "aln": "------MSSPLVLFTALLLVSSTICQGLPDLHKQMTPEQLQSVFHVDTHDAVPHYELVQLQHHENNHNRRRRSIGKGPKVNAALPPHHVKKDLSKNAYYSELKHEALASGGNHLFAPEVSAIKSHNVSFSAFGQHLNLSLRATQGLFKGAPHQLRMWTVGSEPNATHGLDLQEIVHEQHTSNDVGEVFQDEK--NMAAILMRRHMETGDLIMEGSIGHDLVIKPLPHELSPNPEESHHIIYKREASAAEGQL------SDFAFMEP--DDLLASEKLERLQRRQRRSRRSAPSSPDFEDLND---EDEGALDGEPQVAESR-TRSRRQAPYIIYPEVLVIVDYDGYRLHGGDNLQVKRYFISFWNGVDLRYRLLKGPRIRISIAGIIISRGRDATPYLERNRVGRDAIDSAAALTDMGKYLFRERRLPVYD-IAVAITKLDMCRRTSAYGECNRGTAGFAYVGGACVVNKRLEKVNSVAIIEDTGGFSGIIVAAHEVGHLLGAVHDGSPPPSYLGGPGAQRCRWEDGYIMSDLRHTERGFRWSACTVQSFHHFLNGDTATCLHNAPHEDS---ALGRSLPGTLLSLDAQCRRDRGTYACFKDER---VCAQLFC-FDAQTGYCVAYRPAAEGSACGNGYHCLDGRCT---PLPSNIIPDYG---HNYRLVYNKIDNKKDAAEDVESSSEETESQEDETESVEDQDEGTTSS---------------------------EEQEDNKIEQSSAAGGAAAQSTTTARSTTTTTVRTTSTTTTTAKPKSKSFGYLHRSLPERQWMQDNGVLVTTRISSSVSSSSSGSSSGEAAATSTRRPTTTTTTQTPNLFQIYTHELRKQ-------IEYYLHMLQTQQHATKFQPEQQQQQSQQQQSIVEIPLVQKSLTN--------YSVTSSSSSTSNGAKQQPP-----------SNKDENQRQQQQQQQAQQQLQDGLPDEENEATAGIQSNEAIERQKRKFPTTP------------TAATSAAQKSATPATPATSATSAR--------PTPTTAKPITTSSFLDAYFK--KLQALHDAGSASSSTTTTTTTSVSSSVSSATSSKQQHPQQQQQQQVQQIADGSHFLKRTPHRSSLKAYKTSSSSSNNS-----SSQTQQQQQQQQQQYATNYIGDTTNNQPAVLDNSGSASSTTETAKKPKIKTQKLIRRTRVMQTQTQTI------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . : . ** . : . *::*: : . . : : . . . : . * * . . . : :.:: . . .: . . : : . . *. :* . .. : . . .: . : ::: *.*: ::: : : :.: :.* .: . . : ... * ::.. * : .** *:** * : : .*: *::* .. ..... . .*:* .. . . * .* : . *.:*:.* **.* .:*::::: * : :. *. :::.: : : :::.. * .: *.. ::* . . .: :* : . :: :* . : . * : ** * : . ** : .** : .*:. :. ***:** :* **. ** .* .* .* :.*: ** *: :.:.:**...::.** :: :. : .*** : * **: *. *.* :* :*: *:* .:.: . *. :*: *. * * *.** . *.:: ::. * :..:: . .: *.:.: :. ..: . *: : . :*:: : *... . : .. . *: : . :. * . * * * : ** : :: .. . : *:. *. . .: ... :.* : :: ** **: : : . .: :: * : : . : *: : : *::.*.. . .:.:* * .: . ::: .. : :...:. :*: : . *. *: .: * . *.... .:..: : ..* * *.*:: : .. : .: :. ..*.. *. *.. ...* *: . : :. :: .: * ::.* *: : . :. : . :.. **:. : : * ..: *. .* ..* : : .. . .. *: ::* : * * :* ", "identical_positions": 146, "similar_positions": 400, "identity": "11.89%" }, { "cls_id": "homologset.agr.RGD:1308360", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "F1M0Z1-1", "uniprot_id": "TRIO_RAT", "id": "F1M0Z1-1", "name": "Triple functional domain protein", "aln": "MSGSSGGATAPAASSGPAAAASAAGSGCGGGAGEGAEEAAKDLADIAAFFRSGFRKNDEMKAMDVLPILKEKVAYLSGGRDKRGGPILTFPARSNHDRMRQEDLRRLISYLACIPSEEVCKRGFTVIVDMRGSK--WDSIKPLLKILQESFPCCIHIALIIKPDNFWQKQRTNFGSSKFEFETNMVSLEGLTKVVDPSQLTPEFDGCLEYNHEEWIEIRVAFEDYISNAAHMLSRLEELQDVLAKKELPQDLEGARNMIDEHSQLKKKVIKAPIEDLDLEGQKLLQRIQSSESFP----------KKNSGS-----------------GNADLQNLLPKVSTMLDRLHSTRQHLHQMWHVRKLKLDQCFQLRLFEQDAEKMFDWITHNKGLFLNSYTEIGASHPHAMELQTQHNHFAMNCMNVYVNINRIMSVANRLVESGHYASQQIKQIANQLEQEWKAFAAALDERSTLLDMSSIFHQKAEKYMSNVDSWCKACGEVD-LPSELQDLEDAIHHHQGIYEHITLAYSEVSQDGKSLLDKLQR-------PLTPGSSDSLTAS--------------ANYSKAVHHVLDVIHEVLHHQRQLENIWQHRKVRLHQRLQLCVFQQDVQQVLDWIENHGEAFLSKHTGVGKSLHRARALQKRHEDFEEVAQNTYTNADKLLEAAEQLAQTGECDPEEIYQAAHQLEDRIQDFVRRVEQRKILLDMSVSFHTHVKELWTWLEELQKELLDDVY---AESVEAVQDLIKRFGQ-QQQTTLQVTVNVIKEGEDLIQQLRDSAISSNKTPHNSSINHIETVLQQLDEAQSQMEELFQERKIKLELFLQLRIFERDAIDIISDLESWNDELSQQMNDFDTEDLTIAEQRLQHHADKALTMNNLTFDVIHQGQDLLQYVNEVQASGVELLCDRDVDMATRVQDLLEFLHEKQQELDLAAEQHRKHLEQCVQLRHLQAEVKQVLGWIRNGESMLNAGLITASSLQEAEQLQREHEQFQHAIEKTHQSALQVQQKAEAMLQANHYDMDMIRDCAEKVASHWQQLMLKMEDRLKLVNASVAFYKTSEQVCSVLESLEQEYKREEDWCGGADKLGPNSETDHVTPMISKHLEQKEAFLKACTLARRNADVFLKYLHRNSVSMPGMVTHIKAPEQQVKNILNELFQRENRVLHYWTMRKRRLDQCQQYVVFERSAKQALEWIHDNGEFYLSTHT-STGSSIQHTQELLKEHEEFQITAKQTKERVKLLIQLADGFCEKGHAHAAEIKKCVTAVDKRYRDFSLRMEKYRTSLEKALGISSDSNKSSKSLQLDIIPAS-----IPGSEVKLR---DAAHELNEEKRKSARRKEFIMAELIQTEKAYVRDLRECMDTYLWEMTSGVEEIPPGIVNKELIIFGNMQEIYEFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKNKPDSTQLILEHAGSYFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEEGKGEIKDGLEVMLSVPKRANDAMHLSMLEGFDENIESQGELILQESFQVWDPKTLIRKGRERHLFLFEMSLVFSKEVKDSSGRSKYLYKSKLFTSELGVTEHVEGDPCKFALWVGRTPTS-DNKIVLKASSIENKQDWIKHIREVIQERTVHLRGALKEPIHIPKTAPAARQKGRRDGEDLDSQGDGSSQPDTISIASRTSQNTLDSDKLSGGCELTVVIHDFTACN-SNELTIRRGQTVEVLERPHD-KPDWCLVRT---TDRSPAAEGLVPCGSLCIAHSRSSMEMEGIFNHKDSLSVSSNDASPPASVAS---LQP-HMMGAQSSPGPKRPGNTLRKWLTSPVRRLSSGKADGHAKKLAHKHKKSREVRKSADAGSQKDSDDSAATPQDETIEERGRNEGLSSGTLSKSSSSGMQSCGEEEGEEGADAVPLPPPMAIQQHSLLQPDSQDDKASSRLLVRPTSSETPSAAELVSAIEELVKSKMALEDRPSSLLVDQGDSSSPSFNPSDNSLLSSSSPIDEMEERKCSLSLKRRHYVLQELVETERDYVRDLGCVVEGYMALMKEDG----VPDDMKG-KDKIVFGNIHQIYDWHRDFFLGELEKCLEDPEKLGSLFVKHERRLHMYIVYCQNKPKSEHIVSEYIDTFFEDLKQRLGHRLQLTDLLIKPVQRIMKYQLLLKDFLKYSKKASL--DTSELEKAVEVMCIVPKRCNDMMNVGR-LQGFDGKIVAQGKLLLQDTFLVTDQDAGLLPRCKERRVFLFEQIVIFSEPLDKKKGFSMPGFLFKNSIKVSCLCLEENVESDPCKFALTSRTG-DAVETFILHSSSPSVRQTWIHEINQILENQRNFLNALTSPIEYQRNHSGGGGSGSGGSSGGGGGSGGSGASSGGSSSHGSGPSSCSSGPSSSRSRPSRIPQPVRHHPPMLVSSAASSQAEADKMSGMSAPSPSLPTPSNSLALEASLGQPSRLPLSGDSEGHERETEPIPKMKVMESPRKALGSTSGTSQDGNTKDARGNLGPLPLGKTRPGAVSPLNSPLSTTFPSPFGKEAFPPSSPLQKGGS--FWSSIPASPASRPSSFTFPGDS-DSLQR----QTHRHAAPSKDTDRMSTCSSASEQSVQSTQSNGSESSSSSNISTMLVTHEYTAVKEDEINVYQGEVVQILASNQQNMFLVFRAATDQCPAAEGWIPGFVLGHTSAVIMENPDGTFKKSTS-WHTALRLRKKSEKKDKDGKRDGKLENGYRKPREGLSN----KLLNPNYIYDVPPEFVIPLSEVTCETGETVVFRCRVCGRPKASITWKGPEHNTLNNDDHYNISYSDVGEATLKIIGVSTEDDGVYTCIAVNDMGSASSSASLRVLGPGSDGIVVTWKDNFDAFYSEVAELGRGRFAVVKKCDQKGTKRAVATKFVNKKLMKRDQVTHELGILQNLQHPLFVSLLDTFETPTSYVLVLELADQGRLLDCVVRWGSLTEGKVRAHLGEVLEAVRYLHNCRIAHLDLKPENILVDQSLAKPTIKLTDFGDAVQLNTTYYIHQLLGNPEFAAPEIILGNPVSLTADTWSVGVLTYVLLSGVSPFLDDSVEETCLNICRLDFSFPEDYFQGVSQKAKEFVCFLLQEDPAKRPSAALALQEQWLQAGNGSGKGMGVLDTSRLTSFIERRKHQNDVRPIRSIKNFLQSRLLPRV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q0KL02-1", "uniprot_id": "TRIO_MOUSE", "id": "Q0KL02-1", "name": "Triple functional domain protein", "aln": "MSGSSGGATAPAASSGPAAAASAAGSGCGGGAGEGAEEAAKDLADIAAFFRSGFRKNDEMKAMDVLPILKEKVAYLSGGRDKRGGPILTFPARSNHDRIRQEDLRRLISYLACIPSEEVCKRGFTVIVDMRGSK--WDSIKPLLKILQESFPCCIHIALIIKPDNFWQKQRTNFGSSKFEFETNMVSLEGLTKVVDPSQLTPEFDGCLEYNHEEWIEIRVAFEEYISNAAHMLSRLEELQDVLAKKELPQDLEGARNMIDEHSQLKKKVIKAPIEDLDLEGQKLLQRIQSSDSFP----------KKNSGS-----------------GNADLQNLLPKVSTMLDRLHSTRQHLHQMWHVRKLKLDQCFQLRLFEQDAEKMFDWITHNKGLFLNSYTEIGTSHPHAMELQTQHNHFAMNCMNVYVNINRIMSVANRLVESGHYASQQIKQIANQLEQEWKAFAAALDERSTLLDMSSIFHQKAEKYMSNVDSWCKACGEVD-LPSELQDLEDAIHHHQGIYEHITLAYSEVSQDGKSLLDKLQR-------PLTPGSSDSLTAS--------------ANYSKAVHHVLDVIHEVLHHQRQLENIWQHRKVRLHQRLQLCVFQQDVQQVLDWIENHGEAFLSKHTGVGKSLHRARALQKRHEDFEEVAQNTYTNADKLLEAAEQLAQTGECDPEEIYQAAHQLEDRIQDFVRRVEQRKILLDMSVSFHTHVKELWTWLEELQKELLDDVY---AESVEAVQDLIKRFGQ-QQQTTLQVTVNVIKEGEDLIQQLRDSAISSNKTPHNSSINHIETVLQQLDEAQSQMEELFQERKIKLELFLQLRIFERDAIDIISDLESWNDELSQQMNDFDTEDLTIAEQRLQHHADKALTMNNLTFDVIHQGQDLLQYVNEVQASGVELLCDRDVDMATRVQDLLEFLHEKQQELDLAAEQHRKHLEQCVQLRHLQAEVKQVLGWIRNGESMLNAGLITASSLQEAEQLQREHEQFQHAIEKTHQSALQVQQKAEAMLQANHYDMDMIRDCAEKVASHWQQLMLKMEDRLKLVNASVAFYKTSEQVCSVLESLEQEYKREEDWCGGADKLGPNSETDHVTPMISKHLEQKEAFLKACTLARRNADVFLKYLHRNSVSMPGMVTHIKAPEQQVKNILNELFQRENRVLHYWTMRKRRLDQCQQYVVFERSAKQALEWIHDNGEFYLSTHT-STGSSIQHTQELLKEHEEFQITAKQTKERVKLLIQLADGFCEKGHAHAAEIKKCVTAVDKRYRDFSLRMEKYRTSLEKALGISSDSNKSSKSLQLDIIPAS-----IPGSEVKLR---DAAHELNEEKRKSARRKEFIMAELIQTEKAYVRDLRECMDTYLWEMTSGVEEIPPGIVNKELIIFGNMQEIYEFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKNKPDSTQLILEHAGSYFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEEGKGEIKDGLEVMLSVPKRANDAMHLSMLEGFDENIESQGELILQESFQVWDPKTLIRKGRERHLFLFEMSLVFSKEVKDSSGRSKYLYKSKLFTSELGVTEHVEGDPCKFALWVGRTPTS-DNKIVLKASSIENKQDWIKHIREVIQERTVHLRGALKEPIHIPKTAPAARQKGRRDGEDLDSQGDGSSQPDTISIASRTSQNTLDSDKLSGGCELTVVIHDFTACN-SNELTIRRGQTVEVLERPHD-KPDWCLVRT---TDRSPAAEGLVPCGSLCIAHSRSSMEMEGIFNHKDSLSVSSNDASPPASVAS---LQP-HMIGAQSSPGPKRPGNTLRKWLTSPVRRLSSGKADGHAKKLAHKHKKSREVRKSADAGSQKDSDDSAATPQDETIEERGRNEGLSSGTLSKSSSSGMQSCGEEEGEEGADAVPLPPPMAIQQHSLLQPDSQDDKASSRLLVRPTSSETPSAAELVSAIEELVKSKMALEDRPSSLLVDQGDSSSPSFNPSDNSLLSSSSPIDEMEERKCS-SLKRRHYVLQELVETERDYVRDLGCVVEGYMALMKEDG----VPDDMKG-KDKIVFGNIHQIYDWHRDFFLGELEKCLEDPEKLGSLFVKHERRLHMYIVYCQNKPKSEHIVSEYIDTFFEDLKQRLGHRLQLTDLLIKPVQRIMKYQLLLKDFLKYSKKASL--DTSELEKAVEVMCIVPKRCNDMMNVGR-LQGFDGKIVAQGKLLLQDTFLVTDQDAGLLPRCKERRVFLFEQIVIFSEPLDKKKGFSMPGFLFKNSIKVSCLCLEENVESDPCKFALTSRTG-DAVETFVLHSSSPSVRQTWIHEINQILENQRNFLNALTSPIEYQRNHSGGGGSGSGGSSGGGGGSGGSGASSGGSSSHGSGPSSCSSGPSSSRSRPSRIPQPVRHHPPMLVSSAASSQAEADKMSGMSAPSPSLPTPSSSLALEASLGQPSRLPLSGDSEGHERETEPIPKMKVMESPRKAPGSTSGTSQDGNTKDARGNLGSLPLGKTRPGAVSPLNSPLSTTFPSPFGKEAFPPSSPLQKGGS--FWSSIPASPASRPSSFTFPGDS-DSLQR----QTHRHAAPSKDTDRMSTCSSASEQSVQSTQSNG-EGSSSSNISTMLVTHEYTAVKEDEINVYQGEVVQILASNQQNMFLVFRAATDQCPAAEGWIPGFVLGHTSAVIMENPDGTLKKSTS-WHTALRLRKKSEKKDKDGKRDGKLENGYRKPREGLSNKVSVKLLNPNYIYDVPPEFVIPLSEVTCETGETVVFRCRVCGRPKASITWKGPEHNTLNNDDHYSISYSDIGEATLKIIGVSTEDDGIYTCIAVNDMGSASSSASLRVLGPGSDGIVVTWKDNFDAFYSEVAELGRGRFAVVKKCDQKGTKRAVATKFVNKKLMKRDQVTHELGILQNLQHPLLVSLLDTFETPTSYVLVLEMADQGRLLDCVVRWGSLTEGKVRAHLGEVLEAVRYLHNCRIAHLDLKPENILVDQSLAKPTIKLADFGDAVQLNTTYYIHQLLGNPEFAAPEIILGNPVSLTADTWSVGVLTYVLLSGVSPFLDDSVEETCLNICRLDFSFPEDYFQGVSQKAKEFVCFLLQEDPAKRPSAALALQEQWLQAGNGSGKGTGVLDTSRLTSFIERRKHQNDVRPIRSIKNFLQSRLLPRV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75962-1", "uniprot_id": "TRIO_HUMAN", "id": "O75962-1", "name": "Triple functional domain protein", "aln": "MSGSSGGAAAPAASSGPAAAASAAGSGCGGGAGEGAEEAAKDLADIAAFFRSGFRKNDEMKAMDVLPILKEKVAYLSGGRDKRGGPILTFPARSNHDRIRQEDLRRLISYLACIPSEEVCKRGFTVIVDMRGSK--WDSIKPLLKILQESFPCCIHVALIIKPDNFWQKQRTNFGSSKFEFETNMVSLEGLTKVVDPSQLTPEFDGCLEYNHEEWIEIRVAFEDYISNATHMLSRLEELQDILAKKELPQDLEGARNMIEEHSQLKKKVIKAPIEDLDLEGQKLLQRIQSSESFP----------KKNSGS-----------------GNADLQNLLPKVSTMLDRLHSTRQHLHQMWHVRKLKLDQCFQLRLFEQDAEKMFDWITHNKGLFLNSYTEIGTSHPHAMELQTQHNHFAMNCMNVYVNINRIMSVANRLVESGHYASQQIRQIASQLEQEWKAFAAALDERSTLLDMSSIFHQKAEKYMSNVDSWCKACGEVD-LPSELQDLEDAIHHHQGIYEHITLAYSEVSQDGKSLLDKLQR-------PLTPGSSDSLTAS--------------ANYSKAVHHVLDVIHEVLHHQRQLENIWQHRKVRLHQRLQLCVFQQDVQQVLDWIENHGEAFLSKHTGVGKSLHRARALQKRHEDFEEVAQNTYTNADKLLEAAEQLAQTGECDPEEIYQAAHQLEDRIQDFVRRVEQRKILLDMSVSFHTHVKELWTWLEELQKELLDDVY---AESVEAVQDLIKRFGQ-QQQTTLQVTVNVIKEGEDLIQQLRDSAISSNKTPHNSSINHIETVLQQLDEAQSQMEELFQERKIKLELFLQLRIFERDAIDIISDLESWNDELSQQMNDFDTEDLTIAEQRLQHHADKALTMNNLTFDVIHQGQDLLQYVNEVQASGVELLCDRDVDMATRVQDLLEFLHEKQQELDLAAEQHRKHLEQCVQLRHLQAEVKQVLGWIRNGESMLNAGLITASSLQEAEQLQREHEQFQHAIEKTHQSALQVQQKAEAMLQANHYDMDMIRDCAEKVASHWQQLMLKMEDRLKLVNASVAFYKTSEQVCSVLESLEQEYKREEDWCGGADKLGPNSETDHVTPMISKHLEQKEAFLKACTLARRNADVFLKYLHRNSVNMPGMVTHIKAPEQQVKNILNELFQRENRVLHYWTMRKRRLDQCQQYVVFERSAKQALEWIHDNGEFYLSTHT-STGSSIQHTQELLKEHEEFQITAKQTKERVKLLIQLADGFCEKGHAHAAEIKKCVTAVDKRYRDFSLRMEKYRTSLEKALGISSDSNKSSKSLQLDIIPAS-----IPGSEVKLR---DAAHELNEEKRKSARRKEFIMAELIQTEKAYVRDLRECMDTYLWEMTSGVEEIPPGIVNKELIIFGNMQEIYEFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKNKPDSTQLILEHAGSYFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEEGKGEIKDGLEVMLSVPKRANDAMHLSMLEGFDENIESQGELILQESFQVWDPKTLIRKGRERHLFLFEMSLVFSKEVKDSSGRSKYLYKSKLFTSELGVTEHVEGDPCKFALWVGRTPTS-DNKIVLKASSIENKQDWIKHIREVIQERTIHLKGALKEPIHIPKTAPATRQKGRRDGEDLDSQGDGSSQPDTISIASRTSQNTLDSDKLSGGCELTVVIHDFTACN-SNELTIRRGQTVEVLERPHD-KPDWCLVRT---TDRSPAAEGLVPCGSLCIAHSRSSMEMEGIFNHKDSLSVSSNDASPPASVAS---LQP-HMIGAQSSPGPKRPGNTLRKWLTSPVRRLSSGKADGHVKKLAHKHKKSREVRKSADAGSQKDSDDSAATPQDETVEERGRNEGLSSGTLSKSSSSGMQSCGEEEGEEGADAVPLPPPMAIQQHSLLQPDSQDDKASSRLLVRPTSSETPSAAELVSAIEELVKSKMALEDRPSSLLVDQGDSSSPSFNPSDNSLLSSSSPIDEMEERKSS-SLKRRHYVLQELVETERDYVRDLGYVVEGYMALMKEDG----VPDDMKG-KDKIVFGNIHQIYDWHRDFFLGELEKCLEDPEKLGSLFVKHERRLHMYIAYCQNKPKSEHIVSEYIDTFFEDLKQRLGHRLQLTDLLIKPVQRIMKYQLLLKDFLKYSKKASL--DTSELERAVEVMCIVPRRCNDMMNVGR-LQGFDGKIVAQGKLLLQDTFLVTDQDAGLLPRCRERRIFLFEQIVIFSEPLDKKKGFSMPGFLFKNSIKVSCLCLEENVENDPCKFALTSRTG-DVVETFILHSSSPSVRQTWIHEINQILENQRNFLNALTSPIEYQRNHSGGGGGGGSGGSGGGGGSGGGGAPSGGSG-HSGGPSSCGGAPSTSRSRPSRIPQPVRHHPPVLVSSAASSQAEADKMSGTSTPGPSLPPPG--AAPEAGPSAPSRRPPGADAEGSEREAEPIPKMKVLESPRKGAANASGSSPDAPAKDARASLGTLPLGKPRAGAASPLNSPLSSAVPS-LGKEPFPPSSPLQKGGS--FWSSIPASPASRPGSFTFPGDS-DSLQR----QTPRHAAPGKDTDRMSTCSSASEQSVQSTQSNGSESSSSSNISTMLVTHDYTAVKEDEINVYQGEVVQILASNQQNMFLVFRAATDQCPAAEGWIPGFVLGHTSAVIVENPDGTLKKSTS-WHTALRLRKKSEKKDKDGKREGKLENGYRKSREGLSNKVSVKLLNPNYIYDVPPEFVIPLSEVTCETGETVVLRCRVCGRPKASITWKGPEHNTLNNDGHYSISYSDLGEATLKIVGVTTEDDGIYTCIAVNDMGSASSSASLRVLGPGMDGIMVTWKDNFDSFYSEVAELGRGRFSVVKKCDQKGTKRAVATKFVNKKLMKRDQVTHELGILQSLQHPLLVGLLDTFETPTSYILVLEMADQGRLLDCVVRWGSLTEGKIRAHLGEVLEAVRYLHNCRIAHLDLKPENILVDESLAKPTIKLADFGDAVQLNTTYYIHQLLGNPEFAAPEIILGNPVSLTSDTWSVGVLTYVLLSGVSPFLDDSVEETCLNICRLDFSFPDDYFKGVSQKAKEFVCFLLQEDPAKRPSAALALQEQWLQAGN--GRSTGVLDTSRLTSFIERRKHQNDVRPIRSIKNFLQSRLLPRV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LUA6-1", "uniprot_id": "TRIO_DANRE", "id": "Q1LUA6-1", "name": "Triple functional domain protein", "aln": "-----------------------------------------------------------MKAMEVLPILKEKVAFLSGGRDKRGGPVLTFPSRTNHDRIRHEDLRRLIAYLAGIPSEDVCKHGFTVIVDMRGSK--WDSIKPLLKILQESFPCCIHIALIIKPDNFWQKQRTNFGSSKFEFETTMVSLEGLSKVVDPSQLTADFEGSLDYNHEEWIEIRVAFEDFTGNARHLLARLEEMHETVTRKDLPQDLDGARRMIEEHAALKKRVIKAPVEEVDNEGQRLLQRIQSSESYANRTVPVPPGQREGQGQ-----------------PNADTQGLVPRITALLEKLHSTRQNLHQSWHIRKLQLDQCFQLRLFEQDAEKMFDWIMHNKGLFLAGYTEIGNNHPHAMELQTQHNHFAMNCMNVYVNINRIMSVGNRLLEAGHYASQQIKQISGQLEQEWKAFAAALDERSALLEMSATFHQKCDQYMSNVDSWCKACGEVD-LPSELQELEDAIHHHQGLYEHITAAYSEVSQDGKALLDKLQR-------PLTPGSADSLTAS--------------ANYTKAVNHVLDIIHEVLHHQRQLENIWQHRKVRLHQRLQLCVFQQDVQQVLDWIENHGEAFLSKHTGVGKSLHRARALQKRHEDFEEVAQNTYTNADKLLEAAEQLAQTGECDPEEIYQAAHQLEDRIQDFVRRVEQRKVLLDMSVAFHTHVKELWTWLEELQKELLDDVY---AESVEAVQDLIKRFGQ-QQQTTLQFTVNVIKEGEDLIQQLRDLAISSNKTPHNSSINHIESVLQQLDEAQAQMEELFQERKIKLELFLQLRIFERDAIDIISDLDSWNEELSQQMNEFDTEDLTLAEQRLQHHADKALTMNNLAFHVIHQGQELLQYVNEVQASGVELLCDRDVDMATRVQDLLEFLHEKQQELDVAAEQHRRHLEQCVQLRHLQAEVKQVLGWIRNGESMLNAGLITASSLQEAEQLQREHEQFQHAIEKTHQSALQVQQKAEALLQANHYDMDMIRDCAENVASHWQQLMLKMEDRLKLVNASVAFYKTSEQVCSVLESLEQEYKREEDWCGGADKLGPNCESDHVTPMISKHLEQKEAFLKACTLARRNADVFLKYMHRNSVSMPGMLSHVKAPEQQVKNILNELLQRENRVLHFWTMRKRRLDQCQQYVVFERSAKQALEWIHDTGEFYLSTHT-STGSSIHHTQELLKEHEDFHITAKQTKERVKLLIQLADGFCDKGHSHAAEIKKWVTAVDKRYRDFSLRMDKYRTSLEKALGISSDSNKASKDLQLDIIPAS-----APGSEVKLR---DAAHELNEEKRKSARRKDFIMAELIQTEKAYVRDLRECMDTYLWEMTSGVEEIPPGIVNKEHIIFGNMQDLYEFHHNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVNYCKNKPDSTQLILEHAGGYFDEIQQRHRLANSISSYLIKPVQRITKYQLLLKELLTCCEEGKGEIKDGLEVMLSVPKRANDAMHLSMLEGFDENIESQGELILQEAFQVWDPKTLIRKGRERHLFLFEMSLIFSKEVKDSNGRSKYIYKSKLFTSELGVTEHVEGDPCKFALWVGRTPTS-DNKIVLKASGIENKQDWIKHIREVIQERTVHLKGALKEPIHIPKAS-TAKHKGRRDGEDLDSQGDGSSQPDTISLASRTSQNTLDSDKLSGGCELTVVIHDFMAGN-SNELTIRRGQTVEVLERLHD-KPDWCLVRT---TDRSPALEGLVPCAMLCIAHSRSSMEMEGIFNHKDALSVCSNDAIMPGSSAT---LQPGHVMGSQSSPGPKRPGNTLRKWLTSPVRRLSSGKADGHVKKLAHKHKKSRDVRKSADAGSQKDSDDSAATPQDETLEERVRNEGLSSGTLSKSSSSGMQSCGEEEGEEGADAVPLPPPMAIQQHSLLQPDAQDDKTSSRLSVRPSSSETPSAAELVSAIEELVKSKMALEDRPSTLSVEQGDSSSPSFNPSDNSLLSSSSPIDEIEERKTG-FFKKRHYVLLELIETERDYVRDLSLVVEGYMARMREDG----VPDDMKG-KDKIVFGNIQQIYDWHKDFFLGELEKCLEDPDRLGPLFLKHERRLHMYIVYCQNKPKSEHIVSEYIDTYFEDLKQRLGHRLQITDLLIKPVQRIMKYQLLLKDFLKFSKKIGT--DSIELEKAVEVMCIVPKRCNDMMNVGR-LQGFDGKIVAQGRLLLQDTFMVAEPEGGLLNRMKERRVFLFEQIVIFSEPLDKKRGFSMPGYLYKYSIKVNCLGLEDSVDGDPCKFALTSRTSNSSKDAFILHSSHPGVRQVWMLQISQILESQRNFLNALTSPIDYQRNHVEGPGVSGSGVQAGG--SGGQMMAPGGGVGVPAGPGSRSR--PSRIPQPSRLPQPLRHHSPALG-PGAHEHDGPDKLSGMSP-----------------------RPLSRGPSPS-CTTEPEPKVKLPASP-HPKQTDSQQTESPAKEIPRATVAPLALVKPRPGTVSPMASPLAT----PAFKDSIPPCSPGPKTGSSSFWSSVPASPASRPASFTFPGDACDTLSRPNHNQSQRHSTHSKDADRMSTCSSTSEQSIQSTQSNGSESSSSSNISTMLVTQDYVALKEDEINVGQGEVVQILASNQQNMFLVFRAATEQCPAAEGWIPGYVLGHTSAIIPDAPDGTIKKSSSSWHTSLRIRKKSEKREKDNKKEAKLENGYRKSREGLTNKVSVKLLNPNYIYDVLPEFLVPLSDVTCDKGECVTLRCKVCGRPKATVTWKGPEQKTLTNNGHFSIAYSETGEATLRIVGVTSEDDGSYTCIATNDIGSVASSASLRVLGTTSDGIRVMWKDNFESFYTEVAELGRGRFSVVKRCDQRGSKRTVAVKFVNKKLMKRDQVTHEFSVLQRLQHPHLVRLLDTFETSSSYALVLEMSDQGRLLDYIVSWGNLTEEKVAFYLRDILEALQYLHNCRIVHLDLKPENLVVEQSPSQPLVKLTDFGDAVQLNSTPYVHPLLGSPEFAAPELVLGDPVSLSSDLWSLGVLTYVMLSGASPFLDESVEETCLNICRLDFSFPDDYFQGVSQAARDFMCLLLRMEPSKRPPATSCLQEPWLRAGGG-RRSAECIDTSRLISFIDRRKHQNDLRPLTGIRAFLQTRLQPRI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KVD1-1", "uniprot_id": "Q7KVD1_DROME", "id": "Q7KVD1-1", "name": "", "aln": "--------------------------------------------------------MDGQRARDLLTLLQERVVFLTGGRDRRGGPLLCFPATPRRDRLKPEDLRRLLSYLISIPSDAAKNLGFTVIIDMRGNGNCSTNVKTILKVLQEHFSANIHNVVIIKPDNFWQKQRASISSHKYKFETTTVSIESLNKIVESHQLTGDFEGQQLYDHQQWTDARLAIEDFFWQAGDMADRIDDLQEDLNRNDFAEDVPLARHAIDHHNEMRKKITKLPIEDLDMQGKKLLAKINAMAPPGGQAPTNSGGPDMDSGPSSAGQQSQPSQQSRSVGGNPDMSAAVNKALRQIELIHTGQEKLLMLWQHKKVKLDQCFQWRLFEQDCEKMFDWILHNRDVFQMSYVEIGHNYSVAKSLQDEHQKFAVASMNVSVNIDRILAVAARLIESQHYAAQHIKTLAQRLDRTWKDFAAGLDERTAVLQLSVLFHHKAEQYCNSVASWAAACQASQPLPSDIQSLETAIRTHQSLYEAMCQAYTEVHSTSKKLLYQLDHLVQVCNQPPPPGVPDHRKNSNNGSFNKYERQNPAADYSEGASHVLAVIHQILSHHRTLEAKWHQERLRLHQTLALRLFQEDVKQVLDWLKNHGEVFLRKNTGIGRNFHKARVYQTSHDNFENVAQNTYSNAQKLLAAADELARSGEADPNEIYSVARELELQVGSFAERVEQRRRRLDMAVIFYTHEKDVTAWIDKLRTDVSTDETRLSQENLEGIERILQQYQRDQQESSVNVCLTTISQGEALLQEMRSLEYADN----TGSIAALEATLEKLNKQKVELEELWSARKFRADLILRLRYFERDARLLSVQMEMWSEELQHAD---LSRDYQKAEQLIRMHNESVTEIQNATYEVVQQGQDLLQLF---ENAGFISMADATHTAQARIEYLLDFLREREIDLEEMSEAKRAKLEQAVQLCQFQNDANQVISWIRNGEAMLVASFVTPNSLQEAEQLRKGHEQFQIAIEKTHTSAVQVKYRADALINANHYDPLSIDEISDDVTKKWQQLVTYAEERHKLVTASINFYKTAEQVCSVLDSLEREYKREDDWCDGG---GGSDKAQAIVQLISKHQEQKEAFLKACTLARRTAETFLKYANRSQQ----CYQYKGNCEGHVKSKLDKLLTQENQVLDYWTLRKKSLDQCQQFVLFERSAKQAIEWIHNTGEAYLSSRSNLVGISKEETEGLLKEHNEFRSTAKETRERVKLLIQLADSLVEKGHAHASDIKQWVASVDQRYKDFSNRMDSYCEQLEKSLGMSQQQLLLGSDGNSSISSSSGDRHSDPTLEAKLNSSNKENKEINEEKRKSARRKEFIMAELMQTERAYVNDLATCIKCFLEEFRAG-KSVPSALIGQEDVIFGNIKEIHHFHQKIFLRELEKYETMPEDVGHCFVTWASKFDMYVHYCKNKPTSNNLLVQHGGSFFEELQRRLEVDHPLPAYLIKPVQRITKYQLLLKDLLSCCEESHGEIKEGLEVMLNVPKKANDAMHLSLLENCDVSVDKLGEVVLQDAFQAWDTKQIIRKGRERRVFLFELYLLFAKEVKESN-VVKYQFKSKLMTTDMGITEHIEGDETKFAVWTGRSPMLSDCRIVLKATSLETKQIWVKKLREVMQETCFSG-----TSLTLPKSPAKHSGSSQRSSRDLDEQLTEN-DHDRCSLASFGSGNTTDSDNKLGNQEATWVVADYIATSGSNELSVSKGQQVEIVEPPTAGEPDFCLVRLNPQHDDAAVQEGLVPVSVLKPPPG----------SHKHGSGTAANAASSAGSQKSDMQDQSNRSKADALSSSTKRRGFSGRNWLPLMNRKGTDKPPSSKPLVKKPSEKNLRTPQKHAEELAEQQNQQPGASPATVLP---------SSQFPSSTQHPGGAGAGDYEPDEEVGLELPPPMKPIQEPHLIANGPPAFAKDAKESSGNMASPGKMDGNPLSEIEEIVKTTTEQHE-SNSRVDGGGGVENASTNGHGRSHDNNDESHTAVSDKAAA--LKKRQCVFAELMSTEEAYVQDLHEIVNGYMTEINNTNSDIPMPEDLKGGKMKLVFNNIKDIYEWHRDFFLRALRNCQKSPADLGPLIKRSATKFALYYTYCSNKPLSEYIVSAHYQ-YFDSIRQKLGHRLDLSNLIIKPVQRITKYELLIKEIIKATEGAGLYKEVPMLQEAYQQMKVVVKTVNDMMVVLRSLQDFDGEITAQGSLLMQGPMNCVVDAA---QKHRELQVFLFQQIIIFADIEKTKNQYASPIFKYRSHIQLNHMQMKELGD---CRFQIRSTDPKIPEMTIICQAASQENYAGWRDMLNKILQQQNDLIFMLSNPLSTKNK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* ::*.:*:*:*.:*:****:****:* **: ..:**:: ******::** ***: . : *****:****. .:*.:**:*** *.. ** .:************:.:.* *::***. **:*.*.*:*:. *** :*:* *:*::* : *:*:*:: :* .: *:::::: : ::::.:*: **. *:.* ::*:: * *:*::* :*::** :*:: . ..* *.* . : : :: :*: :::* *: :*::****** ******.******* **:.:* .*.*** .:. * .** :*::**: .*** ***:**::*. **:*: ***:*:*: :: :*:: ** ***.****:::*::* **:*.::* ..* **. ** : ***::*.** **: **.:** : **:** . .* ** :*:: * .** .* . * *:*::.. *** :**::* *:* ** *::.::**** * * :**:**:*****::****.** *:**:*:.:*:**. *. *::**:******:**:*** **::**::**.**:***..*::** :: .*..*****: ***:* *:** *:: :*:::*:.:: * *.:*.:: ::::: : **:::::. :..*.:** *:*::*. :.* ..** :*:.*::*:: : ::***:. **:: :*:*:** ***** : ::: *.:**.: :.* *** :: * :.. ::* ::.*::***:*** . : :*. :.* :*:: **:**:*:: :*: :* :* :***.*** ::* :.:**:.******:** *.::*..********:: ***** ****** **:**: :*:*:::***** * : ::.*:.:****: *:* ***.**: ****:*******:***:*****:***.*. * . ::: :. :**** ***************.*:.**** :*.. : * :**. *::*: :**:**.:**:**: ******:*:********:****:.** ***::: .* * ..*: *****::*: ***:*:***********.: :***:**::**: *::**:**:*** **:.* .***:**:*.:. ... : .* .:* * *.**. . :*:***********:******:***:***.** *:. :* *: :* :.:*..::.:* :****:::::.**::***:****** :************.**:*** ****** *.:*:::*.*.:*:*:*:* : :.:.:*****************:**:****.:****:******.***:********:**. * .::. **::**::**.**.* :*******::****: *:*:****:*. ** :****:*:::*:***:*** ***:*.**:* * :*****:.:*.** *:*::***:** . .: :**:. ..:*...***.* . : * *:** * ** ***: *. * * *: *: * . ****:: :** **::* :**:**** * :.. ***** . * . . .**.. ...:* * ..* : *. : . *...** * : *:**. *: :. ...: ..*: * :* *: ::::.::..*:* ** *.:. .* ..*: * :* .. ** .**: *: .. .:: :* .: :* ***:**:. .: ..: *. ...* * ..* ..... :.:: . :*:*: *: **:.**. **:** :*:***: :.: . :*:*:** * *:**.**::**:**:**** *.:* :.* **.*: : :: :* .**.*** **:*** : : :*:.::*:*****::::*:******* **:**:*:::* :: . : *:.* : * :* : **** * * **.***:*.*** **:*..: . . : :* ::***:**:**:: ..*. :: * : :: *::. : ::: : *:* : * ::: ::: * :.:**:.*.::: *:.*:. :.: ", "identical_positions": 936, "similar_positions": 765, "identity": "29.3%" }, { "cls_id": "homologset.agr.RGD:1308361", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z8W5-1", "uniprot_id": "D3Z8W5_RAT", "id": "D3Z8W5-1", "name": "E2 ubiquitin-conjugating enzyme", "aln": "MAASRRLMKELEEIRKCGMKNFRNIQVDEANLLTWQGLIVPDNPPYDKGAFRIEINFPAEYPFKPPKITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQVIQSLIALVNDPQPEHPLRADLAEEYSKDRKKFCKNAEEFTKKYGEKRPVD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P68037-1", "uniprot_id": "UB2L3_MOUSE", "id": "P68037-1", "name": "Ubiquitin-conjugating enzyme E2 L3", "aln": "MAASRRLMKELEEIRKCGMKNFRNIQVDEANLLTWQGLIVPDNPPYDKGAFRIEINFPAEYPFKPPKITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQVIQSLIALVNDPQPEHPLRADLAEEYSKDRKKFCKNAEEFTKKYGEKRPVD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P68036-1", "uniprot_id": "UB2L3_HUMAN", "id": "P68036-1", "name": "Ubiquitin-conjugating enzyme E2 L3", "aln": "MAASRRLMKELEEIRKCGMKNFRNIQVDEANLLTWQGLIVPDNPPYDKGAFRIEINFPAEYPFKPPKITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQVIQSLIALVNDPQPEHPLRADLAEEYSKDRKKFCKNAEEFTKKYGEKRPVD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A1B0GUS4-1", "uniprot_id": "UB2L5_HUMAN", "id": "A0A1B0GUS4-1", "name": "Ubiquitin-conjugating enzyme E2 L5", "aln": "MAASRRLMKELEEIRKCGMENFRNIQVDEANLLTWQGLIVPDNPPYNKGAFRIEINFPAEYPFKPPRITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQVIQSLIALVNDPQPEHPLRADLAEEYSNDRKKFCKNAEEFTKKYGEKRPVD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7K738-1", "uniprot_id": "UBC10_DROME", "id": "Q7K738-1", "name": "Ubiquitin-conjugating enzyme E2-18 kDa", "aln": "MTAPRRLRKELSDLQGNALKSFRDIKADDDNLLRWTGLIVPDNPPYNKGAFRIEINFPAEYPFKPPKINFKTRIYHPNIDEKGQVCLPIISTENWKPATRTDQVVQALVDLINDPEPEHPLRAELAEEFLKDRKKFVKNAEDYTKKHSEKRPAD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:*.*** ***.::: .::.**:*:.*: *** * **********:*******************:*.***:***************:**:*******:****:*:*: *:***:*******:****: :***** ****::***:.****.*", "identical_positions": 111, "similar_positions": 34, "identity": "72.08%" }, { "cls_id": "homologset.agr.RGD:1308362", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4AA54-1", "uniprot_id": "D4AA54_RAT", "id": "D4AA54-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAEVKVEVVG------------IDWQKRCLSLETQLFRFR------LQASKIRELLADKMQELEQRLLEAEQRAENAETQVGVMEEKIKLSN------LKSVDSTGSLHQKYQELLKAMQGK----------------------------DELIGQLQAQLEKQKQTRAEEAKIVQEKAAKIKEWVTVKLAELEMENQHLKTCNQQLVEQVAALQDALEDLR------------MTPSEELLGVPEGTPEGDPVPSGPSAQP--------------VEQDSNPNTQISK----VAVPTP-LGTLQSKDFLSEARS-PEDLSFSMAHPGDIAEA-------KTLQSHLQREGSPSQPFMKP-----GSPRCGSASYREGLITAQGGTFPGTKISAREGGP----------------------GSSLTLPKVRAPSIPRDSFQVAKRHHSQPQVGPGHVDHV-VSIEIG----------ALSALHSSGLPKS-EARAKVREEAEKMEMEELPPMGKKGERESLKPRRGELEGVEPEN-KPPTPPLHRFPSWERRIYAMATSGMQLS---DVSSR-NTASCFASGPPALAFPGAFSGLIYKNVTVP---VYTALKGKATQISNVPFVDE--SSGSDDDCGSQASFRMSVPCSEYRKTSGLGSPRAIKRGVSMSSLSSEG----DYAIPPDACSLDSDYSEPEHKLQRTSAYSTD-----GETLEKSGYLLKMGSRVKTWKRRWFVLRQGQILYYKSPNDVIRKPQGQVDLNSHCQIVRGEEAQTFQLISGNKIYYLTAESPSLLEEWIRVLQSLLKVQVTGPPALHQGGTKPTVKGWLTKVKHGHSKLVWCALVGKTFYYYRSHEDKRPLGCLPVRDAHIEEVDRSCDSDEDYEAGGTGRLLSSHCTLVIHPPEHSPTYLLIGTKHEKDTWLYHLTVAAGGSS-AKVGTVYEQLIGKLMDGEGNPDSPLWRHPMLCYSQEGLCASLTTLPSEALQTEALKLFKSCQLFINVPVEAASVDYHVSLAQTALQVCLVHPELQSEIYCQLMKQIS---------------------------------------------------------------RRP-PQKYSLMQCWQLLALCAPLFLP-QHHFLWYVKQQLQRHADPRSETGQYAIYCQRAVERTLQTGEREARPSRMEVVSILLRNPFHHSLPFSIPVHFANGTYQVVGFDGSSTVDEFLQRLNQETGMRKPSQSGFALFTDDPSGRDLEHCLQGRVKICDAISKWEQTLKELHPGKSEGGTRVVKLMYKNRLYFRSQVKGETERERLLLAFQTSGEIVAGRFPVTKELALEMAALMAQVEYGDLEKPTLPGPGGTPPAKAQHLLQQVLDRFYPRHYRNGAPPEQLRHLAD-MMATKWAALQGCSPPECIRIYLTVARKWPLFGAKLFAAQPAQP----LSSKENTPVWIAVNEDGVSILDQRTMQVNITYPYSSVTTFGGCRDDFMLVIRSIPDQNSGKTRIDKLTFRMPAPKITDTTLVMASYMN--------------------------------------------------------HCSATVNLSAKLPAARQP--------RDLDG-QFFASVSCT-KGSALL----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80TI1-1", "uniprot_id": "PKHH1_MOUSE", "id": "Q80TI1-1", "name": "Pleckstrin homology domain-containing family H member 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAEVKVEVAS------------IDWQKRCLSLETQLFRFR------LQASKIRELLADKMQELEQRLLEAEQRAENAETQVGVMEEKIKLSN------LKSVDSTGTLHQKYQELLRAVQGK----------------------------DELISQLQAQLEKQKQTRAEEAKIVQEKAAKIKEWVTVKLAELEMENQQLKTCNQQLVEQVAALQDALEDLR------------MTPSEELLVVPEGTPERDPVPSGPSDQP--------------VEQDSNPHTQILK----VAVPTPSLGTLQSRDSLSEARS-LEDLRFSMVHPGETAEA-------KTLQSHLQKEGSPSQLCMKP-----GNPKHGSASYRESLVTAQGGTFPGTKTSAREGGP----------------------GSSLTLPKVRAPSIPRDSFQVAKRHHSQPQVGPGHCDHV-VSIEIG----------ALSALHSPGSSKS-EARAKVREEAEKMEMEALPPSGKQEERESLKSRRGELEDVELEN-KPPTPPLHRFPSWESRIYAMATSGMQLS---EVSSRRSNAACYASGPSALAFPGAFSGLVYKNVTVP---VYTALKGKATQISNVPFVDE--SSGSDDDCGSQASFRMSVPCSEYRKTSGLGSPRAIKRGVSMSSLSSEG----DYAIPPDACSLDSDYSEPEHKLQRTSSYSTD-----GEALEKSGYLLKMGSRVKTWKRRWFVLRQGQILYYKSPSDVIRKPQGQVDLNSHCQIVREEEAQTFQLISGNKTYYLTAESPSLLEEWIRVLQSLLKVQVTGPPALHQGGTKPTVKGWLTKVKHGHSKLVWCALVGKTFYYYRSHEDKRPLGCLPVQDAHIEEVDRSCDSDEDYEAGGTGRLLSSHCTLVIHPPEHSPTYLLIGTKHEKDTWLYHLTVAAGGSN-AKVGTVYEQLIGKLMDGEGNPDSPLWRHPMLCYSQEGLCASLTTLPSEALQTEALKLFKSCQLFINVPVEAASVDYHVSLAQTALQVCLVHPELQSEIYCQLMKQIS---------------------------------------------------------------CRP-PQKYSLMQCWQLLALCAPLFLP-QHHFLWYVKQQLQRHADPRSETGQYAIYCQRAVERTLQTGEREARPSRMEVVSILLRNPFHHSLPFSIPVHFANGTYQVVGFDGSSTVDEFLQRLNQETGMRKPSQSGFALFTDDPSGRDLEHCLQGRVKICDAISKWEQTLKELHPGKSEGGTRVVKLMYKNRLYFRSQVKGETERERLLLAFQASGEIVAGRFPVTKELALEMAALMAQVEYGDLEKPTLPGPGGTPPTKAQHLLQQVLDRFYPRRYRNGAPPEQLRHLAD-MMATKWAALQGCSPPECIRIYLTVARKWPLFGAKLFAAQPAQ-----LSPKENTVVWIAVNEDGVSILDHRTMQVNITYPYSSVTTFGGCRDDFMLVIRSIPDQSSGKTRIDKLTFRMPAPKITETTLMMASYMN--------------------------------------------------------HCSATVNLSAKLPAARQP--------RDLDG-QFFASVSCT-KGSALL----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9ULM0-1", "uniprot_id": "PKHH1_HUMAN", "id": "Q9ULM0-1", "name": "Pleckstrin homology domain-containing family H member 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAELKVEAPAS-----------VDWQKRCLTLETQLFRFR------LQASKIRELLADKMQELEQRLLEAEQRAENAETQVGVMEEKVKLSN------LKNVDSEGSLHRKYQELLKAIKGK----------------------------DELISQLEAQLEKQKQMRAEEAKTVQEKAAKIKEWVTLKLAKLEMENQHLKSHNQRLVEQVGSLQDALEAIQ------------IAPSRKLLVPPYGAAEQDSVPSEPGIQP--------------MGQDSGSQAQGLK----AAVLAPSPGALQSKDSVSEAASPLEDSSSSTVHSGETVEA-------KPLQPHLGRESPPHQPCMKL-----LTFRCSSASWGEGLVTAQRGMLPGTKTSAREGGP----------------------GSSLTLPKVRAPGTPRDSIQLAKRHHSQPQVGHGHFGRV-VNIETE----------AFSALHPSGLPEL-ESRARSREEPEKMEMEEPPPAGKNEERESPKALGAELEEVELGN-KPPTPPLHQFSSWESRIYAVATSGMRLS---DMSPR-SNTACCASSPPALVSPGSFSGLVYKNVTVP---VYTALKGRATQISNMPFMDE--SSGSDDDCSSQASFRISVPSSESRKTSGLGSPRAIKRGVSMSSLSSEG----DYAIPPDACSLDSDYSEPEHKLQRTSSYSTDGLGLGGESLEKSGYLLKMGSQVKTWKRRWFVLRQGQIMYYKSPSDVIRKPQGQVDLNSRCQIVRGEGSQTFQLISEKKTYYLTADSPSLLEEWIRVLQSLLKVQATGPPALLRGGTKPTVKGWLTKVKHGHSKVVWCALVGKIFYYYRSHEDKRPLGCLPVRDAHIEEVDRSCDSDEDYEAGGTRRLLSSHCTLVIHPTEHSPTYLLIGTKHEKDTWLYHLTVAAGGSS-AKVGTAYEQLIGKLMDGEGDPDSPLWRHPMLCYSKDGLYASLTTLPSEALQTEALKLFKSCQLFINVPVEAASVDYHVSLAQTALQVCLVHPELQSEIYCQLMKQTS---------------------------------------------------------------CRP-PQKYSLMQCWQLLALCAPLFLP-QHHFLWYVKQQLQRHADPRSETGQYATYCQRAVERTLRTGEREARPSRMEVVSILLRNPFHHSLPFSIPVHFTNGTYHVVGFDGSSTVDEFLQRLNQEIGMRKPSHSGFALFTDDPSGRDLEHCLQGSVKICDAISKWEQAMKELHPGKSEGGTRVVKLMYKNRLYFRSQVKGETDRERLLLASQTSREIVAGRFPINKELALEMAALMAQVEYGDLEKPALPGPGGTSPAKAQHLLQQVLDRFHPRRYRHGAPAEQLRHLAD-MLTTKWATLQGCSPPECIRIYLTVARKWPFFGAKLFAAQPAQ-----LSSKENALVWIAVNEDGVSILDHNTMQVHITYPYSSVTTFGGCRDDFMLVIRSIPDKSSGKSHIEKLIFRMAAPKIAEATFIMASYMN--------------------------------------------------------HCTTTVNPPTNPPGACQL--------WELDGRQFFSSVSCATKGPTLL----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q00IB7-1", "uniprot_id": "PKHH1_DANRE", "id": "Q00IB7-1", "name": "Pleckstrin homology domain-containing family H member 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAEVMESVSTAV-----VPNSSVDWQKRCIALETQLMRFR------LQAGNIRHLLAERMQELEQRVIEADQRAESAEKQVHIMEEKLKSAN------MQPSETENSLYRSYQELSNQIQEK----------------------------DLIVKRLEGQLEKQNLVRAQEAEIIEEKAAKIKDWVTFKLREMETENQQLKKANLKQTEQILMLQDKLQTLLE---------RPMSPAVDTHLVPSSPLHPPSCPGTPPAQEDC-----WRLPGCRLNSSADSKRKITEGCDSAFHSASLLPMLQDKADSPKSSQDGVDATSTVKESAEGVEPSFGVMRDRAMGGASDRDHSSDELNSKFRSQCLRSSSSSSSSSSSAYETPGPGGFDTPTPTPKSPPPVSLSPPLTRLPLSCPFPLALPLGTSMTLPKVRTPLTPRDSIQLVKKHHSQPQPGLERLHQVNVSIDIGNCGSPSCHSLVPGSAPSHGLEET-DIDEGTPESMEVVVEGSEITEAQPNDGDLLDGLTKELEMMDPEALKPPTPPLHRFPSWESRIYAVAKLGMRVS---EACLG-AKTIGRVSTQPQHSTTGPFTHLIYKNISVP---VYSTLKGKATQISSVPLPDD--DSGSEDDSSSLASLHTSTLGPD-KKGSTPGSPRAVKRGVSTSSISSES----DYAIPPDAYSLDSDCSEPEHKVQRTSSYSCESVG--PETLEKTGYLLKMGSQVKAWKRRWFILRNGEILYYKSPSDVIRKPQGQMELNSSCHIARGEGAQTFQLITEKKTFYLAADSPNILEDWIRVLQNVLKVQASGPISMDK-EVKPTARGWLTKVKHGHSKLVWCALIGKVFYYYRNQEDKFPLGQLRVREARVEEVDRSCDSDEDYEAGGRG-FLSSHFTLVVHPKEQSPTYLLVGTKQEKDTWLYHLTVAAGSSASLRVGTEFEQLIGKLLDVDGVSDSALWKREVLCFSKEGLRYPLTTLPSEALQTEAIKLFKSCQLFINVLVESPSIDYHTSLAQNALQVCLTHPELQNEMYCQLIKQTN---------------------------------------------------------------CRT-PHNYALTQCWQLLSLCVALFLP-QHHFLWYLRQYLQRNADPRTEVGKYAVYCQRSVERTLQNGEREAKPSRMEILSILLRNPYHHSLPFSIPVHFMNNTYEVVGFDGSTTVEEFLNTVNQRTGMRKPQISGFALFTDDPSGKDLEHCLQPANKICDVISKWEQALKELHPGKYEG-TRTVRLTYKSRLCFRAQAKGETERERLLLAYQVNDEVLQGHFPVSKELALEVAALMAQVEYGDLDRAAMS-PVGSPQPKTQQTLLQVLERFYPKRYKQECSVEQLRELGERLVATKWSVLRGCTASECVRIYLTVARKWPLFGAKLFNAKPLP-----PSSLDRTQVWLAVNEDGLSVLDY-TMYPLVTYPYQSVITFGGCKEDFMLVVSLIKDQALGKKTVDKLLFAMAKPKILELTLLIASYIN--------------------------------------------------------YWTSSLPGASNQTQSSTLGAQGDKKLWDIDS-RHFPSMTYTTKGPTLL----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W5D0-1", "uniprot_id": "Y34F_DROME", "id": "Q9W5D0-1", "name": "Uncharacterized protein CG43867", "aln": "MQWTAASCDQHDQHDPPAVNRNSIEQRTPANNCEVDPMDATGSTKHPHLPKQREADRPVSGSGGGSSSLTLSGAVTTSMEVTVSTTTTTTIIESSSSTNTTLEKNSPSPAGGSCSSGSGSLSPAYLQHHLQHHGSPLHHLQVHHHTAPPSPLAAVRSAQMGSSVANGAGPAAACLAVCCSPGSSHHHLGHVGHLATGHPLPHQLPHQLPHPSLYPLMAAAQLGYAGSSGPSSLVNSPALGRRKRYTSNSSNCSSQFNNNYAGLDVDSLDDMLR-KLTELEQRVIEAEERAEEAEDKVRAMEQRLSEWPKPPPQQAQHPHSHSHPHQPIPSHPQEQQAKNHCSPSHQASGGATAGAAGSGLPPTQETEKTITSLEIQVEEQRQLRLHDARQIEAKAAKIKEWVNNKLRDLEEQNQLLREQNVKCNQQLELLKNHIANQSQRHSIVGPVRNSLSLDVQDFTGSGSNPEHRRRSESLDPQEIIGRPLTSSYPHHQHRRNLSMEPQELERNLVAAVDGLTLAPLSSISNKAPGGVPTESGVVTRPDSSDTDTAHDYAEIYTPSCEKLPAWMKNNPALMAS-----GGNSSTTTTTTSELGVPRPPTPPLHRFPSWEAKIYQVANDG-----------LAGAGTGTSTAESTASQEPDIQDGMGTNLSNGRRHGHGHGSGTGIGTGDGHG--------TLGSTPGTPLPPSRQQQTASGGFCDISVPVYATVKGRASQIRSMPFTGDSSDDSSDGEDHAVMLTHHSHNSSSTDNTETSTSGSASSPSKSLKTSSSLSPAKRSGSESPKNAKARVHIQSRTSTTPSSRINQHLQPSQHQHHTLSNQNHGHQLGAYTVTPSSGQLSLPRYHANALQPGSLPSPLQHMRGTVISDLSFESGLSDDYALPPDAVSESTCMDASMPSLLMRQSYVDSPSK-KIESLEKMGHLAKLGGKLKTWRKRWFVLKNGSLNYWKSQHDVQRKPQGQIQLDEVCRINRAEGASTFEIDTGKKVYYLTADSHATMDDWIRVLQNVQRRNAT-KLLLSRDDQKPTVQGWVTKVKNGHPKKCWCVLLGKMFLYFKAPAETNPLGQINMRDARVEEVEHVSDSDS--EEREDAAQDQARLTVAIYPAHQGPTYLILSGKPERDNWLYHLTVVSGGGP--SAGTQYEQLVQKLMETDGDPNCVLWRHPILLHTKDTITAPLSSMHTETMQPEAIKLFKSIQLFMSVAVNQPGIDYHVVLAQNALQHALDMPELQTEMICILIKQTSRHLGQKLSVGVQVNKKLGKQTRQLLLCATQSLFTCDTQQAGHAQANGSSPTSIQAPSATPIIDCKSNPPVYSFVQGWQLLALAVSLFVPRSSRLLWYLKLHLSRNADTKTETGKYAAYCERALERTLKNGGRETKPSRMEVLSILLKNPYHHSLPHAIPVHMMNSTYQVVSFDGSTTIEEFQATLAHELGTRDATN-GFCLFSDDPIEKDLEHYLEPLAKLCDVISKWETALREKGSGKFEN-SRVIQLSYKNRLYWKHTIKCETDKERLLLCYQTNSQIVQGRFPLSRELALELASLMSQIDMGDYS---------LEKSRDVGVGLKGLDKFYPYRYRDALGAEQLKDVQE-LLVSKWMLLKGRSTLDCVRIYLTCCRKWPYFGACLFQAKPRQSPESNTASGATPVAWLAVAEDALNVLELSTMAPVARYPYSSVMTFGGCQDDFMLVVS----HDDGGGGEQKLLFAMSKPKILEITLLIADYMNALGHTVPGTPQMNSLTRNGSHRSLRTSQRPNLGGGSAVATGFSTNATTTAHNTLNSHATHTLNSNHSHTLSSSHHAGGGSQPGTLSSGHHQHHHIQQHHQPDILKSTPDHQRIK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** :. :** : .:: *:...: .:* :: *****::**::***.** :* **:::. : .: . :: . . : * : : *: *:*:*. * .:*. :: ******:**. ** .:* :** *: * : :*: *:: : :: . . . . . * . . . : : . *.. . . . : ...: . . ::: . .. .. . *:. : .: :. * . : .. . : * : . :. . .: : : .: : . : . :. . * . * . :. * * . : * . . : :. :.* : *: * .:. :. . *: * ..: . .: : . ** **. *.:* *. ***:**** * .: . . .: .:* . *:*** *:* *:*.::*:*::***:*::*.: *:** ** ******::*:. *:* * * :.**:: : :* :**:*:* :::******.: : :.: : : ***.:**:****:**.* **.*:** * *:: :. *** : :::*::***:: .***. * .:: *:.::* .:.****::. * *:*.*******.:*.. .** :***: **:: :* .:. **:: :* .::: : .*::: :*::*.**:***** ***:.* *: ..:***. ***.*** .* ****.*: * *:** . :. * *:: * ****:*...**:* . ::***:: *.*:**.::*.*:** **:*::****:.* **::*****::****:**:*****.:****: *.**.**.****:*::** : :. * *.. **.**:*** :**** *: *:**.***** :::* .** *. :*.::* **.** :: * **::*****. *.. ::: *:**:.:*****:*:**:*:: ** . .: : *::*:* :*:. ***:.: : ::.:** *:* :. :*:***** .**** *** ** *:* :. . .*:** **.:.:*: ** ***.** *****::*****: : * :** * *. *** : *:::*.*:* : : :: . . : :.. :. : . :* ", "identical_positions": 395, "similar_positions": 430, "identity": "21.16%" }, { "cls_id": "homologset.agr.RGD:1308363", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q86VQ6-1", "uniprot_id": "TRXR3_HUMAN", "id": "Q86VQ6-1", "name": "Thioredoxin reductase 3", "aln": "MER--SPP------QSPGPGKAGDAPNRRSGHVRGARVLSPPGRRARLSSPGPSR-SSEAREELRRHLVGLIERSRVVIFSKSYCPHSTRVKELFSSLGVECNVLELDQVDDGARVQEVLSEITNQKTVPNIFVNKVHVGGCDQTFQAYQSGLLQKLLQEDL-AYDYDLIIIGGGSGGLSCAKEAAILGKKVMVLDFVVPSP-QGTSWGLGGTCVNVGCIPKKLMHQAALLGQALCDSRKFGWEYNQQ-VRHNWETMTKAIQNHISSLNWGYRLSLREKAVAYVNSYGEFVEHHKIKATNKKG-QETYYTAAQFVIATGERPRYLGIQGDKEYCITSDDLFSLPYCPGKTLVVGASYVALECAGFLAGFGLDVTVMVRSILLRGFDQEMAEKVGSYMEQHGVKFLRKFIPVMVQQLEKGSPGKLKVLAKSTEGTETIEGVYNTVLLAIGRDSCTRKIGLEKIGVKINEKSGKIPVNDVEQTNVPYVYAVGDILEDKPELTPVAIQSGKLLAQRLFGASLEKCDYINVPTTVFTPLEYGCCGLSEEKAIEVYKKENLEIYHTLFWPLEWTVAGRENNTCYAKIICNKFDHDRVIGFHILGPNAGEVTQGFAAAMKCGLTKQLLDDTIGIHPTCGEVFTTLEITKSSGLDITQKG-----CUG-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q99MD6-1", "uniprot_id": "TRXR3_MOUSE", "id": "Q99MD6-1", "name": "Thioredoxin reductase 3", "aln": "MEKPPSPPPPPRAQTSPGLGKVGVLPNRRLGAVRGGLMSSPPGRRARLASPGTSRPSSEAREELRRRLRDLIEGNRVMIFSKSYCPHSTRVKELFSSLGVVYNILELDQVDDGASVQEVLTEISNQKTVPNIFVNKVHVGGCDRTFQAHQNGLLQKLLQDDS-AHDYDLIIIGGGSGGLSCAKEAANLGKKVMVLDFVVPSP-QGTTWGLGGTCVNVGCIPKKLMHQAALLGHALQDAKKYGWEYNQQ-VKHNWEAMTEAIQSHIGSLNWGYRVTLREKGVTYVNSFGEFVDLHKIKATNKKG-QETFYTASKFVIATGERPRYLGIQGDKEYCITSDDLFSLPYCPGCTLVVGASYVGLECAGFLAGLGLDVTVMVRSVLLRGFDQEMAEKVGSYLEQQGVKFQRKFTPILVQQLEKGLPGKLKVVAKSTEGPETVEGIYNTVLLAIGRDSCTRKIGLEKIGVKINEKNGKIPVNDVEQTNVPHVYAIGDILDGKPELTPVAIQAGKLLARRLFGVSLEKCDYINIPTTVFTPLEYGCCGLSEEKAIEMYKKENLEVYHTLFWPLEWTVAGRDNNTCYAKIICNKFDNERVVGFHLLGPNAGEITQGFAAAMKCGLTKQLLDDTIGIHPTCGEVFTTLEITKSSGLDITQKG-----CUG-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K0G3-1", "uniprot_id": "A0A0G2K0G3_RAT", "id": "A0A0G2K0G3-1", "name": "thioredoxin-disulfide reductase (NADPH)", "aln": "---------------------------------WGVPYLGP---------------------------------------------------------------------DKGCTDLACFVQVTIRVAAP------------------------RQLARTD------------SWLRGMRVRERSWKLMSK-----------------CLGGTCVNVGCIPKKLMHQAALLGHALQDARKYGWDYNQQ-VKHNWETMREAIQNHIGSLNWGYRVTLREKGVTYVNSFGEFVELHKIKATNKKG-QETFYTASKFVIATGERPRYLGIQGDKEYCITSDDLFSLPYCPGNTLIVGASYVGLECAGFLAGLGLDVTVMVRSVLLRGFDQEMAEKVGSYLEQQGVKFQRKFTPIL---LEKGLPGRLKVVAKSTEGPETVEGTYNTVLLAIGRDSCTRKIGLEKIGVKINEKNGKIPVNDVEQTNVPHVYAIGDVLEGKPELTPVAIQAGKLLARRLFGISLEKCDYINVPTTVFTPLEYGCCGLSEEKAIEMYTKENLEVYHTFFWPLEWTVAGRDNNTCYAKIICNKFDNDRVIGFHLLGPNAGEVTQGFAAAMKCGLTKQLLDDTIGIHPTCGEVRIRRERERERERERERERERESVCVCVCVCV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M1PCD1-1", "uniprot_id": "A0A8M1PCD1_DANRE", "id": "A0A8M1PCD1-1", "name": "thioredoxin-disulfide reductase (NADPH)", "aln": "----------------------------------MPPIENDAGR-----------------EQIRSKIKELIDSSAVVVFSKSFCPFCVKVKDLFKELNVKYNTIELDLMEDGTNYQDLLHEMTGQKTVPNVFINKKHIGGCDNTMKAHKDGVLQKLLGEGSEVYDYDLIVIGGGSGGLACSKEAATLGKKVMVLDYVVPTP-QGTAWGLGGTCVNVGCIPKKLMHQTALLGTAMEDARKFGWEFAEQ-VTHNWETMKTAVNNYIGSLNWGYRVSLRDKNVNYVNAYAEFVEPHKIKATNKRG-KETFYTAAQFVLATGERPRYLGIPGDKEFCITSDDLFSLPYCPGKTLVVGASYVALECGGFLAGLGLDVTIMVRSILLRGFDQDMADRAGEYMETHGVKFLRKFVPTKIEQLEAGTPGRIKVTAKSTESEEVFEGEYNTVLIAVGRDACTGKIGLDKAGVKINEKNGKVPVNDEEQTNVPHIYAIGDILEGKWELTPVAIQAGKLLARRLYAGATMKCDYVNVPTTVFTPMEYGSCGHPEEKAIQMYGQENLEVYHSLFWPLEFTVPGRDNNKCYAKIICNKLDNLRVIGFHYLGPNAGEVTQGFGAAMKCGITKDQLDNTIGIHPTCAEIFTTMEVTKSSGGDITQSG-----CUG-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VNT5-1", "uniprot_id": "TRXR2_DROME", "id": "Q9VNT5-1", "name": "Thioredoxin reductase 2, mitochondrial", "aln": "--------------------------------MSTIKFLR----------------------------------------------------------SSTHNALRSSLGWCRLAASRP--------------------------------------------RYDYDLVVLGGGSAGLACAKEAAGCGARVLCFDYVKPTP-VGTKWGIGGTCVNVGCIPKKLMHQASLLGEAVHEAVAYGWNVDDTNIRPDWRKLVRSVQNHIKSVNWVTRVDLRDKKVEYVNSMATFRDSHTIEYVAMPGAEHRQVTSEYVVVAVGGRPRYPDIPGAVELGITSDDIFSYEREPGRTLVVGAGYVGLECACFLKGLGYEPTVMVRSIVLRGFDRQMSELLAAMMTERGIPFLGTTIPKA---VERQADGRLLVRYRNTTTQMDGSDVFDTVLWAIGRKGLIEDLNLDAAGVKTHDD--KIVVDAAEATSVPHIFAVGDIIYGRPELTPVAILSGRLLARRLFAGSTQLMDYADVATTVFTPLEYSCVGMSEETAIELRGADNIEVFHGYYKPTEFFIPQKSVRHCYLKAVAEVSGDQKILGLHYIGPVAGEVIQGFAAALKTGLTVKTLLNTVGIHPTTAEEFTRLSITKRSGRDPTPAS-----CCS-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P91938-1", "uniprot_id": "TRXR1_DROME", "id": "P91938-1", "name": "Thioredoxin reductase 1, mitochondrial", "aln": "--------------------------MNLCNSRFSVTFVRQCST--------------------------ILTSPSAGIIQNRGSLTTKVPHWISSSLSCAHHTFQRTMNLTGQRGSRDSTGATGGNAPAGSGAGAPPPFQHPHCDRAAMYAQPVRKMSTKGGSYDYDLIVIGGGSAGLACAKEAVLNGARVACLDFVKPTPTLGTKWGVGGTCVNVGCIPKKLMHQASLLGEAVHEAAAYGWNVDEK-IKPDWHKLVQSVQNHIKSVNWVTRVDLRDKKVEYINGLGSFVDSHTLLAKLKSG--ERTITAQTFVIAVGGRPRYPDIPGAVEYGITSDDLFSLDREPGKTLVVGAGYIGLECAGFLKGLGYEPTVMVRSIVLRGFDQQMAELVAASMEERGIPFLRKTVPLS---VEKQDDGKLLVKYKNVETGEEAEDVYDTVLWAIGRKGLVDDLNLPNAGVTVQKD--KIPVDSQEATNVANIYAVGDIIYGKPELTPVAVLAGRLLARRLYGGSTQRMDYKDVATTVFTPLEYACVGLSEEDAVKQFGADEIEVFHGYYKPTEFFIPQKSVRYCYLKAVAERHGDQRVYGLHYIGPVAGEVIQGFAAALKSGLTINTLINTVGIHPTTAEEFTRLAITKRSGLDPTPAS-----CCS-----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *: :.: : :*****************::*** *: :: :**: : : :*. : :::.:* *:** *: **:* * *:*. . * : *.: * . *: .*:*.* **** .* * * *****:** ** **:***.*:.***. ** *:* : *:****::*****::*:: . : :*: * . * :* *:: * :.. .. ::*** *:**.. .:.* **. :.. *: *: * *.*. ::*:**:: .: ******: :*:***:**:. : ** ::.******:**.. * .** *:: :::*::* : * *: :. :. . ** * :.: .. :: *:* :** ***: ***.**:* *:* . * :*:***** .* : : * ", "identical_positions": 163, "similar_positions": 137, "identity": "24.47%" }, { "cls_id": "homologset.agr.RGD:1308364", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LWA5-1", "uniprot_id": "A0ABK0LWA5_RAT", "id": "A0ABK0LWA5-1", "name": "", "aln": "----METASEKRQ-VVFLTILLLLWKSDAETIRYSMPEETESGYLVANLAKDLGLRVGELATRGARIHHKGNKDLLQLDAETGNLILKEKPDREVLCRATEPCVLHFQIILENPVQFFQTELQLTDINDHAPEFPDRKMLLKISESAQPGTMFPLKAAQDPDIGSNAVQNYTVSPNLHFHVITHSRTDGRKYPELVLDRALDREEQPELTLTLIALDGGAPSRSGTTTVHIEVVDINDNPPKFDQSLYEVQIPENSPLNALVATVSARDLDAGIHGTVIYSL-FQGGELSQPFEIDEVAGEIRLKGTLDFEATPYYNIEIVATDPGGFSGKCSVAIQVVDVNDNAPKLTISSLNSSIPEN-APEAVVAVFSVSDPDSGENGRIVCSIQNELPFLLKPTFENYYTLVTERPLDRESRADYNITITVSDLGIPRLTTQHTIIVQVSDINDNAPAFNQTSYTLLVRENNSPALHIGTISATDSDTGANAHISYLLLPLYDMQLALTSLVSINQENGQLFVLRALDYETLQTFEFSVGATDHGSPALSSQALVRVVVLDDNDNAPFVLYPLQNASVPCTELLPRAAEPGYLVTKVVAVDCDSGQNAWLSFQLLKATEPGLFNVWAHNGEVRTTRLLSERDVPKHKLLLVVKDNGEHQRSATVTLHVLLVDGFSQPYLPLPEVARDPVQDDEDVLTLYLVIALASVSSLFLFSVLLFIGMRLCKR--AREASLGVCSVPEGHFPGHLVDVSGTGTLSQSYQYEVCLTGDSGTGEFKFLKPMISNLMVQD----------------PGREVKESPPCRDSFVFS----------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91VE5-1", "uniprot_id": "Q91VE5_MOUSE", "id": "Q91VE5-1", "name": "", "aln": "MEMTLAKTPENRQ-VLFFTILLLLWKSCADAIIYSIPEETESGYLVANLAKDLGLRVGELAIRGARIHYKGNKELLQLDAETGNLFLKEKPDREVLCRATEPCVLHFQIILENPVQFFQTELQLTDINDHSPEFPDRKMLLKIPESAQPGTTFPLKAAQDPDIGSNAVQNYTVSPNLHFHVVTLSRSDGRKYPELVLDRALDREEQPELTLILTALDGGAPPRSGTTEVHIEVVDINDNAPQFIQSLYEVQILENSPLDALVATVSARDLDAGIYGKVAYSL-FQDDGISQPFVIDEITGEIRLKGALDFEATPYYNMEIVATDPGGFSGKCTVVIQVVDVNDNAPKLTISSLNSSIPEN-APETVVAVFSVSDPDSGENGRMVCSIQNELPFLLKSTFENYYTLVTEGTLDRESKAEYNITISVTDLGTPRLTTQHTITVQVSDINDNAPTFTRTSYTMFIRENNSPALHIGTISATDSDAGSNAHITYSLLPPHDPQLTLTSLVSINEDNGQLFALRALDYEALRAFEFHVRATDRGSPALSSQALVLVVVLDDNDNEPFVLYPLQNSSAPCKELVPRAAEAGYLVTKVVAVDRDSGQNAWLSFQLLKATEPGLFSVWAHNGEVRTTRLLSERDAPKHRLLLVVKDNGDPPRSASVTLHVLLVDGFSQPYLPLSEVVQDPAQEGDDALTLYLVIALASVSSLFLISVLLFVGMKLCKR--ARSPSLGVCSVPEGHFPGHLVDVSGTGTLSQSYQYEVCLSGDSGTGEFKFLKPMISNLMVQD----------------PEREVKESPHCRDSFVFS----------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y5E4-1", "uniprot_id": "PCDB5_HUMAN", "id": "Q9Y5E4-1", "name": "Protocadherin beta-5", "aln": "METALAKTPQKRQ-VMFLAILLLLWEAGSEAVRYSIPEETESGYSVANLAKDLGLGVGELATRGARMHYKGNKELLQLDIKTGNLLLYEKLDREVMCGATEPCILHFQLLLENPVQFFQTDLQLTDINDHAPEFPEKEMLLKIPESTQPGTVFPLKIAQDFDIGSNTVQNYTISPNSHFHVATHNRGDGRKYPELVLDKALDREERPELSLTLTALDGGAPPRSGTTTIRIVVLDNNDNAPEFLQSFYEVQVPENSPLNSLVVVVSARDLDAGAYGSVAYAL-FQGDEVTQPFVIDEKTAEIRLKRALDFEATPYYNVEIVATDGGGLSGKCTVAIEVVDVNDNAPELTMSTLSSPTPEN-APETVVAVFSVSDPDSGDNGRMICSIQNDLPFLLKPTLKNFYTLVTQRTLDRESQAEYNITITVTDMGTPRLKTEHNITVLVSDVNDNAPAFTQTSYTLFVRENNSPALHIGSVSATDRDSGTNAQVTYSLLPPQNPHLRLASLVSINADNGHLFALRSLDYEALQAFEFRVGATDRGSPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGDSGQNAWLSYQLLKATEPGLFSMWAHNGEVRTARLLSERDAAKHRLVVLVKDNGEPPRSATATLHVLLVDGFSQPYLPLPEAA--PAQAQADSLTVYLVVALASVSSLFLFSVLLFVAVRLCRR--SRAAPVGRCSVPEGPFPGHLVDVSGTGTLSQSYHYEVCLTGDSGAGEFKFLKPIIPNLLPQG----------------AGEEIGKTAAFRNSFGLN----------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N6G0-1", "uniprot_id": "A0A8M1N6G0_DANRE", "id": "A0A8M1N6G0-1", "name": "", "aln": "----MAKTSKLCLGKWRLWITSLLFCVTAADVRYSVPEETKTKFVIGNLSKDVNLDYNRLRFRKARLDYQGDRRYCEIDLDSGNLFVSERIDREMLCGTASPCIMHFEFILENPLELHNIALEVQDVNDNPPVFPKGSIKLEISEGAPTGSKLQLTRARDLDVGINSVQTYILSQNKHFVLDTKSSKD--RYVDIVLKNSLDRETRGEHSLILSAVDGGNPPNSGTVVIEVVVIDMNDNAPLFLQPLYNARLSENSALGTSVIKITATDEDEGANGEIKYYINHLSDNTKQLFKIDENYGEISVIGQLDHEKASSYEVEVQAEDGGGQTGHCKVVIEIDDVNDNAPVISVKSLKNKIPENTTPGTEIAVINVKDQDSGENSRISCSISPNLPFQLQPYIKSYFILTTSSSLDREQIDNYNVTIIATDGGIPPLFSNISLNIQVSDVNDNSPRFELQSYFIYISENKQAGTSVCSVSANDPDWRQNGTVLYSLVPSEVNGVPMSSFLSINGDTGVIHTVRSFDYEQFRNFSVKVVARDNGSPPLSSNVTVKVFITDENDNSPQILYPVPDGKTLMTEMVPKATLSGSLVSNVIAVDADSGQNAWLSYQILKSTDPGLFTIGLHSGEIKTQRDISESDNMKQNLVISVKDNGQPSLSTTCVVNLLISDNLSE----VPELKDMSYEDNNSKLTSYLIIALVSVCTFFLTFIILMLAVKFCHRRKPRLLFDGAVAVPSAYLPPNYADVDGAGTIRSSYNYDAYLTTGSRTSDFKFVSSYNENTLPAGGILDKSKIDFNMLRLSDVGECTEQKPPNTDWRFPPNQRPGPSGAGARPEEAGAGAGVIAGTGPWPNPPTEAEQLQAMMAAANASEATATLGPRYNLQYGPDYRQNVYIPGSTATLTANPQQQVLQQALPPPQALPPTEAPKAAQTPASKKKPTKKDKK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .:.: : * **: : : **:****:: : :.**:**:.* ..* * **:.::*:: ::* .:***:: *: ***::* ::.**::**:::****:::.: *:: *:**:.* **. .: *:*.*.: .*: : *. *:* *:* *:**.* :* * ** : * . * :* ::**..:**** : * :* * *:*** *..***. :.: *:* ***.* * *.:*:.:: ***.*.: * ::* * * * * : * : . .. .* * *** .** : **.* :. *::*: * * ** :*:*.*.*:: ******* :::.:*.. *** :* : :**:.*.* ***:*.*: ***. :*** *:. ::.:: *.*. .****. :**:** .:* * * * :: .: : ***:***:* * ** : : **:... : ::**.* * *. : * *:* : ::*::*** :.* :..:*::*** :: *.. * * *.***.***:. * *.: * *** * :***: :... .*::*:*: .* **::*:*** *********:*:**:*:****.: *.**::* * :** * *:.*:: *****: *:: .:::*: *.:*: :.* . : . ** **::**.**.::** ::*::.:::*:* .* * :**.. :* : .**.*:**: .**:*:. *: .* :.:***:.. * : . * : . .: : ", "identical_positions": 291, "similar_positions": 284, "identity": "30.89%" }, { "cls_id": "homologset.agr.RGD:1308365", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P43308-1", "uniprot_id": "SSRB_HUMAN", "id": "P43308-1", "name": "Translocon-associated protein subunit beta", "aln": "MRLLSFVVLALFAV-----TQAEEGARLLASKSLLNRYAVEGRDLTLQYNIYNVGSSAALDVELSDDSFPPEDFGIVSGMLN--VKWDRIAPASNVSHTVVLRPLKAGYFNFTSATITYLAQEDG-PVVIGSTSAPGQGGILAQREFDRRFSPHFLDWAAFGVMTLPSIGIPLLLWYSSKRKYDTP-KTKKN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9CPW5-1", "uniprot_id": "SSRB_MOUSE", "id": "Q9CPW5-1", "name": "Translocon-associated protein subunit beta", "aln": "MRLLAVVVLALLAV-----SQAEEGARLLASKSLLNRYAVEGRDLTLQYNIYNVGSSAALDVELSDDSFPPEDFGIVSGMLN--VKWDRIAPASNVSHTVVLRPLKAGYFNFTSATITYLAQEDG-PVVIGSTSAPGQGGILAQREFDRRFSPHFLDWAAFGVMTLPSIGIPLLLWYSSKRKYDTP-KPKKN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7F8A8-1", "uniprot_id": "F7F8A8_RAT", "id": "F7F8A8-1", "name": "Translocon-associated protein subunit beta", "aln": "MRSLVVVVLALLAV-----SQAEEGARLLASKSLLNRYAVEGRDLTLQYNIYNVGSSAALDVELSDDSFPPEDFGIVSDLRHHFFFLNPWASASNVSHTVVLRPLKAGYFNFTSATITYLAQEDG-PVVIGSTSAPGQGGILAQREFDRRFSPHFLDWAAFGVMTLPSIGIPLLLWYSSKRKYDTP-KPKKN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VUZ0-1", "uniprot_id": "Q9VUZ0_DROME", "id": "Q9VUZ0-1", "name": "Translocon-associated protein subunit beta", "aln": "MFKHLLTLFALCAVFSTCLSEDETRARLLVSKQILNKYLVEKSDLLVRYTIFNVGSGAATKVRLVDSGFHPEAFDVVGGQPT--AVVDRIAPQTNFTHVLVVRPKAFGYFNFTAAEVSYKAVEESETLQLAVSSEPGEGGIVNLNEYNKRFSSHFFDWVAFAVMTLPSLAIPLALWHQSKSKYERSGKNKKH", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* ..::** ** :: * ****.**.:**:* ** ** ::*.*:****.** .*.* *..* ** *.:*.. : *. :*.:*.:*:** ******:* ::* * *:. .: :. :* **:***: .*:::***.**:**.**.******:.*** **:.** **: . * **:", "identical_positions": 85, "similar_positions": 58, "identity": "44.27%" }, { "cls_id": "homologset.agr.RGD:1308366", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BWR8-1", "uniprot_id": "RHPN2_MOUSE", "id": "Q8BWR8-1", "name": "Rhophilin-2", "aln": "---MTDTLLPAAPQPLEKEGDDYFRKGCNPLAQTGRSKLQNQRAALNQQILKAVRMRTGAENLLKVATNQKVREQVRLELSFVNSDLQMLKEELEGLNISVGVYQGTEEAFTIPLIPLGLKETKEVDFSIVFKDFILEHYSEDSYLYEDDIADLMDLRQACRTPSRDEAGVELLMSYFIQLGFVESRFFPPTRHMGLLFTWYDSFTGVPVSQQTLLLEKASVLFNIGALYTQIGTRCNRQTQAGLESAVDAFQRAAGVLNYLKETFTHTPSYDMSPAMLSVLVKMMLAQAQESVFEKVCLPGIQNEFFVLVKVAQEAAKVAEAYRQLHAAMSQEPVKENIPYSWASVAYVKAYHYGALAHYFAATLLIDHQLKPGADEDHQEKCLSQLYDRMPEGMTPLATLKNAGQRVLLGKGHLHRAIGFHEESLREANLCKKLRDIQVLRDVLSAAHQRTQLKHTQHREDDDLLNLIDAPDVLPKTEREVKITFPDFSKVTVTDFFQKLGPLSVFSASKRWSPPRGIHFTVEEGDLGFTLRGNTPVQVHFLDPHCSASLAGAKEGDYIVSIQGVDCKWLTVSEVMKLLKSFGGEEVEMKVVSLLDSTS-SMHNKCATYSVGMQKTYSMICLSMDDDDKADKTKKISKKLSFLSWGTSKNRQKSASTLCLPEVGLARSQNKKKLPTPFSLLNSDSSLY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A8N7-1", "uniprot_id": "D4A8N7_RAT", "id": "D4A8N7-1", "name": "Rhophilin-2", "aln": "MASMTDALLPAAPQPLEKESDDYFRKGCNPLAQTGRSKLQNQRAALNQQILKAVRMRTGAENLLKVTTNQKVREQVRLELSFVNSDLQMLKEELEGLNISVGVYQGTEEAFTIPLIPLGLKETKEVDFSIVFKDFILEHYSEDSYLYEDDIADLMDLRQACRTPSRDEAGVELLMSYFIQLGFVESRFFPPTRHMGLLFTWYDSFTGVPVSQQTLLLEKASILFNIGALYTQIGTRCNRQTEAGLESAVDAFQRAAGVLNYLKETFTHTPSYDMSPAMLSVLVKMMLAQAQESVFEKICLLGIQNEFFVLVKVAQEAAKVAAAYRQLHAAMSQEPVKENIPYSWASVAYVKAYHYGALAHYFAATLLIDHQLKPGADEDHQEKCLSQLYDRMPEGMTPLATLKNDGQRVLLGKGHLHRAIDYHKESLREANLCKKLRDIQVLRDVLSAAHQRTQLKYTQHQQDDDLLNLIDAPDVLPKTEREVKITFPDFSKVTVTDFFQKLGPLSVFSASKRWSPPRGIHFRVEEGDLGFTLRGNTPVQVHFLDPHCSASLAGAKEGDYIVSIQGLDCKWLTVSEVMKLLKSFGGEEVEMKVVSLLDSTS-SMHNKCATYSVGMQKTYSMICLSMDDDDKADKTKKISKKPSFLSWSTSKNRQKSASTLCLPNVGLARPQNKKKLPTPFSLLNSDSSLY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8IUC4-1", "uniprot_id": "RHPN2_HUMAN", "id": "Q8IUC4-1", "name": "Rhophilin-2", "aln": "---MTDALLPAAPQPLEKENDGYFRKGCNPLAQTGRSKLQNQRAALNQQILKAVRMRTGAENLLKVATNSKVREQVRLELSFVNSDLQMLKEELEGLNISVGVYQNTEEAFTIPLIPLGLKETKDVDFAVVLKDFILEHYSEDGYLYEDEIADLMDLRQACRTPSRDEAGVELLMTYFIQLGFVESRFFPPTRQMGLLFTWYDSLTGVPVSQQNLLLEKASVLFNTGALYTQIGTRCDRQTQAGLESAIDAFQRAAGVLNYLKDTFTHTPSYDMSPAMLSVLVKMMLAQAQESVFEKISLPGIRNEFFMLVKVAQEAAKVGEVYQQLHAAMSQAPVKENIPYSWASLACVKAHHYAALAHYFTAILLIDHQVKPGTDLDHQEKCLSQLYDHMPEGLTPLATLKNDQQRRQLGKSHLRRAMAHHEESVREASLCKKLRSIEVLQKVLCAAQERSRLTYAQHQEEDDLLNLIDAPSVVAKTEQEVDIILPQFSKLTVTDFFQKLGPLSVFSANKRWTPPRSIRFTAEEGDLGFTLRGNAPVQVHFLDPYCSASVAGAREGDYIVSIQLVDCKWLTLSEVMKLLKSFGEDEIEMKVVSLLDSTS-SMHNKSATYSVGMQKTYSMICLAIDDDDKTDKTKKISKKLSFLSWGTNKNRQKSASTLCLPSVGAARPQVKKKLPSPFSLLNSDSSWY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8MT19-1", "uniprot_id": "RHN2P_HUMAN", "id": "A8MT19-1", "name": "Putative rhophilin-2-like protein RHPN2P1", "aln": "----------------------------------------------------------------------------------------MLKEELEGLNISVGIYQNTEEAFTVPLIPLGLKETKDIDFSVILKDFILEHYSEDGYLYEDEITDLMDPRQACRTPSRDEARVELLMTYFIQLGFAWIRFKKYNTSPRIFFYRYDSLNGVLVSQQNLLLEKASVLFNTGALYTQIGTWRYWQMQAGLQSAIDAFQRAAGVLNYLKETFTHTPSYDMSPAMLSVLVKMMLTQAQESVFEKISLPGIRNEFFMLVKVAQEAAKVGEVYQQLHAAMSQALVKENIPYSWASLACVKAHHYTALAHYFTAILLIDHQVKPGMDLDHQEKCLSQLYDHMPEGLTPLATLKNDQQRRQLGKSHLHRAMAHHEESVREASLCKKLRSIEVLQKVLCAAQERSRLTYAQHQEDDDLLNLIHAPSVVAKTEQEP------------------KGPLSVFLANKQWMPPRSNRFTAEEGDLGFTLRGNAPVEVHFLDPYCSALVAGARGGDYIVSIQLVDCKWLTVSEVMKLLKSFGEDEIEMKVVSLLDSTS-SMHNKSATYSVGMQKTYSMICLAIDDDNKTDKTQKISKKLSFLSWGTNKNRQKSASTLCLPSVGAARPQVKKKLPSPFSLLNSDSSSY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6TNR1-1", "uniprot_id": "RHPN2_DANRE", "id": "Q6TNR1-1", "name": "Rhophilin-2", "aln": "---MTDTLIPNGCKSNGPVENGYFKKGCNPFAQTGRSKLQNKRAVLNQKIIKQMRMRAGAENLLKATSNNKVREQVVLELSYVNSDLQLLMEQLEGLNSSVEVYQNVQESSSIPLIPLGLKETKDVDFSVPLKDFILEHYSEDGSNFQNQIDDLMDLRQACRTPSRNNSGVDLIANYFSQLSFLETRFFSPTRQIGIFFTWYDSFTGMPVCQNNISLEKASMLFNMAALYSQIGTRADRQTLAGLEDAIAAFQKSARVLHFLKETFTHTPSYDMSPAMLSMLLRLMLAQAHECLFEQITLPGIRNEFFCLLKMAQEAAKVAETYAQVHQSMIETPITKNVPFFWTTMSQLKINHYNSLAHYFVSTALLDHQLNPSDDEDKQEKALSQLYDAMPEGRSPLDILKNKDERRRIGKAHLQRSIMGHEEAIRTHCRCRHLQKLDILSDILRASLNRSLTKFEQNDKEDEFTDYMLAPDIISKTEKKAEMEIPAATKVKVTDLFQRLGPLSVFSAKQRWTAPRTIRLILQDRDLGFTLKGDAPVQIQSLDPLCPAAAGGLKEGDYLVAVGDTDCKWMGVSDVMKLLKDVDEEGINIRVVSMMDSSSQPMATKSATYCGGLSKTYSMICLAHDEDDKNPKSRKVAKKPSFLSFGLKN--KKSSSTLSLPNADYSRPWNRP--SANYSNSHHESGLY", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* *:***** ** :**..:*: ::***********::**:: :***********. ::::* **** *********::: *:*: .** **.* ** . ::* ***:.*: *.*:.: *****:*** .***:**** * ***:.*: ***::* **::**:****************:*:::**:**:*.:**:: * **:**** *:*:*******. .* *:* :* : :.:*:*: *:::: :* ** :*****.: *:***::*. * *:***.****** **** :** *** :* :**.**:*:: *:*::* *::*:.:::* .:* *: :*: .. *: ::*:: : : **.::.***:: ****** *.::* .** :: :: ******:*::**::: *** *.* .* : ***:*:: ****: :*:******... : ::::***::**:* .* .*.***. *:.********: *:*:* *::*::** ****:. .: :**:***.**... :*. : .: :* : :*. *", "identical_positions": 278, "similar_positions": 187, "identity": "40.29%" }, { "cls_id": "homologset.agr.RGD:1308367", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5EBJ4-1", "uniprot_id": "ERMIN_MOUSE", "id": "Q5EBJ4-1", "name": "Ermin", "aln": "MTDTPETLSGTECNGDRPPENGQQPSSQTRQETTDADETQAYYKVEPSLEDLPAKENQEETGNTKGNILPKGPEDEKILNENPEENLFVVHQAIKDLSLQEISAEDMAFREGHPWKKIPPNSSNLEVSRQKERTAQQQLEQRGDAS-------TTEIEWLGFQKSRPVDILHSKCDEEEEEEEEVWNEEINEEDVDECAEEE--DEVRVIEFKRKHREGSPLKEESLAREDSPLGSPGSQPGTPDEQPVFGKKGDIARNSYSRYNTISYRKIRKGNTKQRIDEFESMMHL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5RJL0-1", "uniprot_id": "ERMIN_RAT", "id": "Q5RJL0-1", "name": "Ermin", "aln": "MTDTPVTLSGSECNGDRPPENGQQPSSQTR-KTTDADETQTYYGVEPSLQHLPAKENQEESGNSKGNVLPRGSEDEKILNENTEENLFVVHQAIQDLSLQETSAEDTVFQEGHPWKKIPLNSHNLDMSRQKERIVHQHLEQREDESA---AHQATEIEWLGFQKSSQVDILHSKCDEE----EEVWNEEINEEDVDECAEDEGEDEVRVIEFKRKYREGSPLKEESLAREDSPLSSPSSQPGTPDEQLVLGKKGDIARNSYSRYNTISYRKIRKGNTKQRIDEFESMMHL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8TAM6-1", "uniprot_id": "ERMIN_HUMAN", "id": "Q8TAM6-1", "name": "Ermin", "aln": "MTDVPATFTQAECNGDKPPENGQQTITKISEELTDVDSPLPHYRVEPSLEGALTKGSQEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEE----QKVWDEEIDDDDDDNCNNDE--DEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQAVTPDEQPTLGKKSDISRNAYSRYNTISYRKIRKGNTKQRIDEFESMMHL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***.* *:: :*****:*******. :: : **.*.. .:* *****: :* .*** : :**:* ... ::*:*:**.**:**:**:** ****** **:: .*:*** *:*** .. * :: ***** ..* *::. * . ::*******:*. .*:**** *** ::**:***:::* *:* ::* *********:*:.* * :***. * *****.*..**. ***** .:***.**:**:******************************", "identical_positions": 161, "similar_positions": 75, "identity": "55.52%" }, { "cls_id": "homologset.agr.RGD:1308368", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q2M2H8-1", "uniprot_id": "MGAL_HUMAN", "id": "Q2M2H8-1", "name": "Probable maltase-glucoamylase 2", "aln": "MAR----KLSVLEVLLIIFCLIVVTIDILLLLLVLEE------------------TSDTSFTPECPEIPQSERIDCTPDQEVTEDICRWQYKCCWSPVADANVPRCFFPWNWGYEASNGHTNTSTGFTAQLKRLPSPSLFGNDVATTLFTAEYQTSNRFHFKITDFNNIRYEVSHENINLVDGIADASNLSYYVEVTDKPFSIKIMRTSNRRVLLDTSIGPLQFAQQYLQLSFRLPSANVYGLGEHVHQQYRHNMTWKTWPIFTRDATPTEGMINLYGAHTFFLCLEDARGSSFGVFLMNSNAMEVTLQPAPAITYRTIGGILDFYVFLGNTPEQVVQEYLELVGRPFFPPYWSLGFQLSRRDYGGINKLKEVVSRNRLAEIPYDVQYSDIDYMDGKKDFTVDEVAYSGLPDFVKELHDNGQKYLIIMNPGIS----KNSNYEPYNNGSLKRVWILGSNG-FAVGEGYPGPTVFPDYTNPVCTEWWTDQVAKFHDHLEFDGVWIEMNEVSSLLQASN-NQCESNNLNFPPFLPRVLDHLLFARTLCMDTEFHGGLHYDIHSLYGHSMARTTNLALETIFMNN-RSFILSRSTFAGSGKFAAHWLGDNAATWDDLRWSIPTILEFNLFGIPMVGANICGYNNNVTEELCRRWMQLGAFYPLPRNHNGPGFRDQDPAAFGVDSLLLKSSRHYLNIRYTLLPYLYTLFYHAHTRGETVARPLVHEFYQDSATWDVHEQFLWGPGLLITPVLYEGVDEVKAYIPDATWYDYETGVAISWRKQLVNMLLPGDKIGLHLRGGYIFPTQKPNTTTEASRRNSLGLIIALDYKREAKGELYWDDGVSKDAVTEKKYILYDFSVTSNHLQAKIINNNYMDTDNLMFTDITILGMDKQPANFIVLLNNVATSS-PSVVYNASTKVVTITDLQGLVLGQEFSIRWNLPVSDLEKFNCYPDDPTASEESCRQRGCLWEDTSTPGVPTCYYDTIPNYVASDIQYLNTSITADLSLPMAPESAAAAAS-----DSLSAKISFLHLKVIYHTATMLQVKIYDPTNKRYEVPVPLNTPPQPVGDPENRLYDVRIQNNPFGIQIQRKNSSTVIWDSQLPGFIFNDMFLSISTRLPSQYIYGFGETEHTTFRRNMNWNTWGMFAHDEPPAYKKNSYGVHPYYMALEEDGSAHGVLLLNSNAMDVTLQPTPALTYRTTGGILDFYIVLGPTPELVTQQYTELIGRPAMIPYWALGFHLSRYGYQNDAEISSLYDAMVAAQIPYDVQHVDIDYMNRKLDFTLSANFQNLSLLIEQMKKNGMRFILILDPAISGNETQ-YLPFIRGQENNVFIKWPDTNDIVWGKVWPDLPNVIVDGSLDHETQVKLYRAYVAFPDFFRNSTAAWWKKEIEELYANPREPEKSLKFDGLWIDMNEPSNFVDGSVR-GCSNEMLNNPPYMPYLESRDKGLSSKTLCMESQQILPDSSPVEHYNVHNLYGWSQTRPTYEAVQEVTGQRGVIITRSTFPSSGRWGGHRLGNNTAAWDQLGKSIIGMMEFSLFGIPYTGADICGFFGDAEYEMCVRWMQLGAFYPFSRNHNNIGTRRQDPVAWNSTFEMLSRKVLETRYTLLPYLYTLMHKAHVEGSTVVRPLLHEFTDDRTTWDIDRQFMLGPAILISPVLETSTFEISAYFPRARWYDYSTGTSSTSTGQRKILKAPLDHINLHVRGGYILPWQEPAMNTHSSRQNFMGLIVALDDNGTAEGQVFWDDGQSIDTYENGNYFLANFIAAQNILQIQTIHNKYLSDSNPLKVGYIRIWGVN-TYVTQVS-------------------------------------------------------------------------------FTYDNRQFMETNFKSEPYNQILTIQLTDKTIN----------------LEKLTEVTWIDGGP-----VLPTPTKTSTIPMSSHPS----------------------------------------------PSTTNATSSETITSSASANTTTGTT---------------------------------------DTVPITTTSFPSTTSVTTN-------------------------------------------------------------------------------TTVPDTTSPFP-----------------TSTTNASTNATVPITTTPFPTSTIGVTTN----------ATVPNTTAP-----------------------------FPTNASTASTNATVPITTTCFATSTIGVTTNATVPDTTAPFPTNTTTASTNATIP---ITTTPFATSTISVTTSTTVPD------------------------------------TTAPFPTS--------------------------------------------------------------------TTSASTNATPVPITTTLFATSTIGVTTGTTVP-------------------------------------------------------DTTAPFP-------------------------------------------------------------------------------TSTTSTSTSATVPITTTPSPTNTADANTSNTVPN--------------------------TTMPSPTSSTTVSTIATVP----------------------------------------------------------------ISVTPSLTSTADATISTTVLIATTSSLTGTTDVSTSTTINNISTPVQTNTTNASTSTNVANITATSHTSTDDTVP--------------------------------------------------------------------------------------------------------------NNTVPVTAIPSLANTGVDT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TSNSFSIMTTSFSESTNAMNTTVIMATTSPTSTDVASTNNDASMTNFLLATMSAGNITSNSIS----------------------ITTTSFGNSVPF--------------------------------------------------------VTTPSPSTDATTTSNNTNPG--MTTYYQTSPTIPTHTLTSIPSSITSILSMFPTSNTFTTDKITNFTTPTNANTIIFNTLD--------------------------------------------------------------------------------------------------------------TKSTMVIDATVTTTSTKDNTMSPDTTVTSIDKFTTHITQFATPHSATTTTLALSHTSLAPTNLSNLGT----------------------------------MDITDADNSSSVTGNTTHISVSNLTTASVTITATGLDSQTPHMVINSVATYLPITATSATTDTTNITKYALNTTTPDSTVHTSATAPTYIANAINATQVP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A571BDS5-1", "uniprot_id": "A0A571BDS5_MOUSE", "id": "A0A571BDS5-1", "name": "Sucrase-isomaltase, intestinal", "aln": "MAR----KLSVLEVLLIIFNVVVLAVDILLLLLVLEN------------------PSG-SFTPECPDISESERIDCAPGQVVTEDACRWQRKCCWKPVADPKVPACFFPRNWGYEVTNVLTNESTGLTAQLKKLSSPSLFGNDIVDALLTAEYQTSNRFHFKITDFNEIRYEVSSENNNLMNGTTKKSSLSYDVEVIKNPFSIRVLRKSNKRVLLDTGIGPLQFDQQYLELSFRLPSSNVYGLGEHVHQQYLHNMSWNTWPIFTRDTTPTQGKINLYGAHTFFLCLEDTSGASFGVFLMNSNAMEVTLQPAPAITYRTTGGILDFYIFLGNTPEQVVQEYLEVVGRPFLPSYWSLGFQLSRRDYGGIDGLRNVVNRTRVAEIPYDVQYSDIDYMNGNKVFTIDEQAYPMLSEFVEDLHDNGQKYIIILHPGIAN---HDPDYETYRNGSKNRVWIMSSSG-FAVGKGYAGESVFPDFTNPDSIAWWTQQVTEFHKSLEFDGVWIEMDELATTAQGSNDNKCESNNLNSPPFTPSILNGSLLVNTLCMDTEFYSGLHYDVHSLYGYNMAKATNLALDAVFNSTTRNFVLSRSTFAGSGKFAGHWLGNNAATWDDLRWSIPSILEFNLFGIPLVGANICGYKNNVTEELCRRWMQLGAFYPLSRNHNGPEYTDQDPAAFGLNSLLLQSSRHYLNIRYTLLPYLYTLFYRAHTLGETVARPLVHEFYQDPATWAVHEQFLWGPGLLITPVLYEGKNQVKAYIPDAIWYDYETGLAIQPRKQFIDMPLPSDRIGLHLRGGYIFPTQEPSRTTNDSRKNPMGLIIALDYKREAKGQLYWDDGVSKGTVSERKYILYDFSVTSNSLQAKIINNGYVDPNDIKFTDIRILGMDKEPTDCNVLTNNNIIPI-SSYNYNASAKMLIISNLTELKLGQEFSIEWKLVVSDLEKFNCFPENPAVSEESCKQRGCLWEQATIPGVPTCFYDTIPQYAASNIQYQPTGITMDLTLLENSTSAQAAAAPRVVSDPLSGKISSLKLSVTYHTENMLQVKIYSTSKKRYEVPVPLTIPSPPLNTCENCLYDVSVKTNPFGLQIQRKSSGTVIWDSQLPGFTFSEMFLSISTRLPSQYIYGFGETDHSSFRKNMSWNTWGMFARDEPPSYKKNSYGVHPYYMALEDDSNAHGVLLLNSNAMDVTLQPTPALTYRTIGGILDFYMVLGPTPELVTQQYTQLIGRPAMTPYWALGFQLSRYGYKSDAEISDLYSAMVAAEIPYDVQHVDIDYMDRKLDFTLSPSFQNLSVLINQMKTKGMRFLLTLDPVISGNETH-YLTFIRGQEDNVFIKRPDSDDIVWGKVWAELPNVNVDGSLDHETQLKLYRAHVAFPDFLRNSTATWWKKEIKELYSNPQEPQKSLKFDGLRIDMNEPSNFVDGAVG-GCRNDTLNKPPYMPDLEARNVGLNSKTLCMESEQILPDGSRVPHYDVHSLYGWSQTRPTYEAVQEVTGERGIVITRSTFPSSGRWGGHWLGDNTAAWDQLGKSIIGMMEFSLFGIPYTGADICGFFGDAEYEMCIRWMQLGAFYPFSRNHNTAGTRRQDPVAWNSTFEEYSRKVLRVRYSLLPYLYTLMHEAHTKGSTVIRPLLQEFTEDNTTWDIDYQFMLGPAILISPVLERNTFEIHAYFPRACWYDHSTGSGYNSSGEWKTLPAPLDHINLHIRGGYILPWQEPGMNTYDSRQNLMGLTVALDNDGKAEGQLFWDDGQSIETYEKGNYFLATFRAEKNSLKIQIPHNKFLSDTNPLRIGYIRIWGLNNTYVVQVF-------------------------------------------------------------------------------CTYNNQQFSQDDFTSEPHNQKLTIRLTGKNMN----------------LEKLTEVTWVYGDP-----VAPTPNATSVLPTSPHPS----------------------------------------------ESST-----ETVTSPALITT------------------------------------------------------PETISTFT--------------------------------------------------------------------------------TTLPTTTTPFP-----------------TGPITN-TSDMMPATTTATDTSTDVNTTN----------TTYPDTTT--------------------------------TTSSHTNTSDVLPETTTTPETTTVDITTSTTFPNTTTPFPTSPPTTNTSDVMP---VTTTATGTSTVINTTSTTFPN------------------------------------TTTPFPTS--------------------------------------------------------------------SPTTN-ASDVIPVTTTTTETSTVVNTTNTTFP-------------------------------------------------------NTTTPFP-------------------------------------------------------------------------------TSPPTTNTSDVIPVTTTTTETSTVVNTTNTTFPN--------------------------TTTPFPTGPPTTNTSDVIP----------------------------------------------------------------VTTTATETSTVVNTTNTTFPNTTTPFPTSPLTTNASDVIPVTTTTPETTTVDITTSTTFPNTTTPFPTSPPTTNT--------------------------------------------------------------------------------------------------------------SDVMPVTTTATGTSTVINT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TSTTFPNTTTPFPTSPPTTNASDVIPVTTTTT------------------------ETSTVVN----------------------TTNTTFPN------------------------------------------------------------TTTPFPTSPPTTNTSDVIPV--TTTTTETS-TVVNTTNTTFPNTTTPFPTSPPTTN--ASDVILVTTTATETSTVVN-----------------------------------------------------------------------------------------------------------------------ATNTTFPNTTTPFPTSPPTTNTSDVIPVTTTATETSTVVNATNTTFPNTTTPFPTSPPT-----------------------------------------TNASDVIPVTTTTTEISIIDNTTSTT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZTX4-1", "uniprot_id": "D3ZTX4_RAT", "id": "D3ZTX4-1", "name": "Sucrase-isomaltase, intestinal", "aln": "MARRRFKKFSTLELVLIVLLLILFIVAVVLIVLLANSTEPNAVDAETTGTPDTTLTRTTLNFPECPVLSEAERINCIPDQSSNKDTCD-QRGCCWDPQGSISVP-CYFSRNHGYKMESDLANTTAGFTAALKNLASAPVFGNGIENILLTAEYQTSNRFHFKLTDQTKERYEVPHEHVKPFSGNA-ASSLNYNVEVFKEPFSIKVTRKSNNRVLFDSSIGPLLFSDQFLQLSTHLPSANVYGLGEHVHQQYRHDMNWKTWPMFARDTTPNEDGNNLYGVQTFFLCLEDNSGLSFGVFLMNSNAMEVTLQPTPAITYRITGGILDFYVFLGNTPEQVVQEYLELIGRPTLPSYWTLGFQLSRYDYGSLDKMKIVVERNRAAQLPYDVQHADIDYMDQRKDFTYDPVNFKGFPEFVKELHNNGQKLVIILDPAISNNSLSSNPYGPYDRGSAMKVWVNSSDGNALIGKVWPGTTVFPDYTSPNCAVWWKKEIELFHNEVEFDGIWIDMNEVSNFVDGSV-SGCSQNNLNYPPFTPKVLDGNLFSKTLCMDAVQHWGKQYDVHNLYGYSMAIATEEAVKTVFPDK-RSFILTRSTFAGSGKFAAHWLGDNTATWKDLQWSIPGMLEFNLFGIPMVGADICGFAMNTYEELCRRWMQLGAFYPFSRNHNGQGYKDQDPASFGEDSLLLNSSRHYLNIRYTLLPYLYTLFYRAHSRGDTVARPLLHEFYEDSNTWDIDRQFLWGPGLLITPVLDQGAEKVKAYVPDATWYDYETGEQLAWRKQSVEMELPEDKIGLHLRGGYIFPTQQPATTTEASRKNPLGLIIALDKNKEAKGELFWDDGQTKDTVAKNLYLFTEFSATQNRLDVTISSPNYKDPNNLEFQEIKIFGT-QEFRNVKVKQNGVLLQMSPQVNYNSNLKVATITNIH-LMLGEAYTVEWDIFTRDEEKIDCYPDEHGVSEANCIARGCIWEVSNTPGVPHCYFAN-ELYSVSNIQYNSHGATADIFLKASTYSNAFPSTP----------VNQLQLKVAYHKDQMLQFKIYDPNRSRYEVPVPLNIPSAPSSTPEGRLYDVFIKENPFGIQIRRKSTGTVIWDSQLLGFTFNDMFIRISTRLPSTYIYGFGETEHTTFKIDMNWQTWGMFSRDEPPGYKKNSYGVHPYYMGLEEDGNAHGVLLMNSNAMDVTFQPMPALTYRTVGGILDFYVFLGPTPEIVTEQYTELIGRPVMVPYWSLGFQLCRYGYENDTEIANLYDEMVAKRIPYDVQYSDIDYMERQLDFKLNPKFSGFPDLINRMKDNGMRVILILDPAISGNETEPYPAFTRGVENDVFISYPNNGGIVWGKVWPDYPNITVDPSLDWDSQVQQYRAYVAFPDFFRDSTALWWKNEIKELHSNSQDPAKSLKFDGLWIDMNEPSSFVNGAVPSGCTDTTLNRPPYMPHLEARDRGLSSKTLCMESEHILPDGSRVRHYDVHSLYGWSQTRPTYEAMQEVTGERGIVITRSTFPSSGRWGGHWLGDNTAAWDQLGKSIIGMMDFSLFGISYTGSDICGFFQDAEYEMCVRWMQLGAFYPFSRNHNTIGTKRQDPVSWNETFEDISRSVLETRYTLLPYLYTLMYKAHKEGSTVVRPLLHEFLADRETWNVDKQFLLGPAFLVSPVLELNARNVTAYFPKAQWYDYYTGADINSTGEWRTLPAPLEHINLHVRGGYILPWQQPALNTNLSRKKPLGLLIALNENKEARGELFWDDGQSKDTVAKNIYLFSEFSVTQNRLDVTISSPNYK-DPNNLEFQEIKIFGTQEIRNVKVKQNGVLLQMSPQVNYNSNLKVATITNIHLVLGEAYTVEWDIYSKDVERIDCYPDEHGVSEANCTARGCIWEVSNTPGVPHCYFANELYSVSNIQYDSHGATADISLKASPYSNAFPSTPVNQLQLKVTYHKDQMLQFKIYDPNRSRYEVPVPLNIPSAPSSTPEGRLYDVFIKENPFGIQIRRNSTGTVIWDSQLLGFTFNDMFIRISTRLPSTYIYGFGETEHTTFKIDMNWQTWGMFSRDEPPGYKKNSYGVHPYYMGLEEDGNAHGVLLMNSNAMDVTFQPMPALTYRTTGGILDFYVFLGPTPEIVTQQYTELIGRPVMVPYWSLGFQLCRYGYENDTEIANLYDEMVAKQIPYDVQYSDIDYMERQLDFKLSPKFSGFPDLINRMKDNGMRVILILDPAISGNETEPYPAFTRGVENDVFISYPNNGGIVWGKVWPDYPNITVDPSLDWDSQVQQYRAYVAFPDFFRNSTALWWKNEIKELHSNSQDPAKSLKFDGLWIDMNEPSSFVNGAVPSGCTDTTLNRPPYMPHLEARDRGLSSKTLCMESEHILPDGSRVRHYDVHSLYGWSQTRPTYEAVQEVTGERGIVITRSTFPSSGRWGGHWLGDNTAAWDQLGKSIIGMMDFSLFGISYTGSDICGFFQDAEYEMCVRWMQLGAFYPFSRNHNTIGTKRQDPVSWNKTFEDISRSVLETRYTLLPYLYTLMYKAHKEGSTVVRPLLHEFLADRETWNVDKQFLLGPAFLVSPVLEPNARNVTAYFPKAQWYDYYTGADINSTGEWRTLPAPLEHINLHVRGGYILPWQQPALNTNLSRKKPLGLLIALNENKEARGELFWDDGQSKDTVAKNIYLFSEFSVTQNRLDVTISSPNYKDPNNLEFQEIKIFGTQEILNVKVKQNGVLLQMSPQVNYNSNQKVATITNIHLVLGEAYTVEWDIYSKDMERIDCYPDEHGVSEANCTARGCIWEVSNIPGVPHCYFANELYSVSNVQYDSHGATADISLKASPYSNAFPSTPVNQLQLKVTYHKDQMLQFKIYDPNHSRYEVPVPLNIPRTPSSTVDGRLYDVLIKENPFGIQIRRKSTGTVIWDSQLLGFTFNDMFIRISTRLPSTYIYGFGETEHTTFKIDMNWHTWGMFSRDEPPGYKKNSYGVHPYYMGLEEDGNAHGILLLNSNAMDVTFQPMPALTYRTTGGILDFYVFLGPTPEIVTQQYTELIGRPVMVPYWSLGFQLCRYGYENDAEIANLYDEMVAKQIPYDVQYSDIDYMERQLDFKLNPKFSGFPDLINRMKDNGMRVILILDPAISGNETEPYPAFTRGVENDVFIRYPNNGDIVWGKVWPDYPNIVVNSSLDWDSQVEQYRAYVAFPDFFRNSTALWWKKEIEELYRNTQEPAKSLKFDGLWIDMNEPSSFVNGAVPSGCSDTTLNRPPYMPYLEARDRGLSSKTLCMESEHILPDGSRVRHYDVHSLYGWSQTRPTYEAVQEVTGERGIVITRSSFPSSGRWGGHWLGDNTAAWDQLGKSIIGMMDFSLFGISYTGSDICGFFQDAEYEMCVRWMQLGAFYPFSRNHNTIGTRRQDPVSWNKTFEDISRSVLETRYTLLPYLYTLMYKAHTEGSTVVRPLLHEFVSDRETWSIDKQFLLGPAFLVSPVLEPDARNIRSYFPRALWYDYYTGENINSTGEWRTLSAPLEHINLHVRGGYILPWQRPALNTHLSRKNPLGLIIALDENKEARGELFWDDGQSKDLTTNNILCKFSVTQNRLDVSTSKSTYTDPDNLTFQEIKIFGTQALYNVTVKHNGMVNQMSPQVSYDPNMKVALITGIQLLLNESYTVEWDGSIRDGEKMDCYPDQHGASEANCTARGCVWEVSNSPGVPFCYFVNELYSVSNVQYDSHGASANISLKASPYSNAFPSTPVNELQLKVTYHKDEMLQFKIYDPNHSRYEVPVPLNIPSSPSSTPDNRSYDVFIKENPFGIEIRRKGTGSVIWDSRLLGFTFNDMFIRISTRLPSTYIYGFGETEHTTFKIDMNWHTWGMFSRDEPPGYKKNSYGVHPYYMGLEEDGNAHGILLMNSNAMDVTLQPMPALTYRTTGGVLDFFVFLGPTPELVTQQYTELIGRPVMVPYWSLGFQLCRYGYENDTEIANLYDDMVAKKIPYDVQYSDIDYMERQLDFKLNPKFSGFPDLINRMKHDGMRVILILDPAISGNETEPYPAFTKGVENDVFIRYPNNGDIVWGKVWPDYPNITVDPSLDWDSQVEQYRAYVAFPDFFRNSTALWWKDEIKELHSNTQDPAKSLKFDGLWIDMNEPSSFVNGAVPSGCSDATLNRPPYMPHLEARDRGLSSKTLCMESEHILPDGSRVRHYDVHSLYGWSQTRPTYEAVQEVTGERGIVITRSTFPSSGRWGGHWLGDNTAAWDQLGKSIIGMMDFSLFGISYTGSDICGFFQDAEYEMCVRWMQLGAFYPFSRNHNTIGTRRQDPVSWNKTFEDISRSVLETRYTLLPYLYTLMYKAHTEGSTVVRPLLHEFVSDRETWNIDKQFLLGPAFLVSPVLEPNARTVAAYFPKARWYDYYTGVDINARGEWKTLQAPLEYINLHVRGGYILPWQEPAMNTQLSRKKSMGLKAALNDEGLAEGWLFWDDGKSINITNQYYLARFSVSQNTLQTHEMFNNYITGTVPLYLGYIEIWGLSSPSITSVRISGKNLNEEVLADYNTTTQILRVNVTDKNISLHAFQSLTWS", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** *:*.**::**:: :::. : ::*::*: :. . **** :.::***:* *.* .:* * * ***.* .. .** *:*. * **: . :* ::*:** **.*.*..:***.: *:*************:** .: ****. *: : ..* : *.*.* *** .:****:: *.**.***:*:.**** * :*:*:** :***:************* *:*.*:***:*:**:**.:. ****.:******** * ******************:****** *******:***************::*** :*.**:******* ***.:: :: **.*.* *::*****::*****: .* ** * : :.:**::**:**** :**:.*.*: . * .* .** :**: .*.* :*: :.* :****:*.* . **..:: **. :****:**:*:*::. :.* . *..**** *** * :*: *: .*****: : * :**:*.***:.** :*: *:.::* .. *.*:*:***********.****:*:***.**:**** :*********:***:***: *. ***************:.***** : *****:** :****:*********************:**: *:******:****:*. ** :..************** :* ::****:*** ******* : *** ::* ** *:**************:* **: **:*.:******* ::****:*:**** :*.:*::. *:: :**.*.* *:..* . .* *.::: * :* *:* :: : * *. .. **:. *: *::: * **: :::.*.: . * **::*:*:: .** .* ***:** :. **** *:: . * .*:*** . * *: * . * .:: :. *:*.* **. ***.***.....********. *. * . *. **** :: ****:**:**.:.******** ** *.:**: ******* ********:*::*: :*.*:*****::****.*************.**:*..******:********:** ******* *******:.******:**:***:*****.* ***:***:*.****:.*:**:.**. *** .******: *****:*:***.*...*..:. **::** :***.:* ***.******. * .* ** *::***. *:...*******.: **: ** *** ::*:: ***:******:*:*** ***:**:**::*.::* ******** *******.**:*:* ** : **.***** **:*: **.********::****.* * **:**.*************:*****:**::*************** **:****************:******.***:****** *******:****************. **:*****:**.*** **.**..**:*********::** :****:****:** *. **::* **:****:*:***** .: :: ****:* ***: **:. .*:*: : * ***:*****:*********:*.:** **:: :** :**::: *.*::******* :* :. *::: * . :* *.: :: *.* *.. *:*:* : .:* : *. : :: :.:. * *. . . .* : : .* *.* . * *. . *: ** :. * * .:. . : ** . . . * * ... .* . *: *. . . :. * .: :.:. ::. : :.* . .* . :* .:.*: :. .*: * :.**:* .. . :. ..* * * *. :.*: ** ... :.. .:.* . ... ... . ** . .. : .. .:. :: . : . . . :.. : . . : . : . * . :. * .:.: ** . : * * ..:* :.. * : * . :. . : * ::* . . * . . * : * .* : * :: * :* * : . . . . : .: :: :: . : .*:. * . . .: . * * .. . .. .. * . . .:. :.. .. ", "identical_positions": 1079, "similar_positions": 657, "identity": "23.82%" }, { "cls_id": "homologset.agr.RGD:1308369", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z898-1", "uniprot_id": "D3Z898_RAT", "id": "D3Z898-1", "name": "Deoxynucleoside triphosphate triphosphohydrolase SAMHD1", "aln": "-------------------------------MQRPDSEQPAKRSRCDGSPRTPPSTRPAAANESADP--ESSDLRTWGPEDVCSFLEKRGFREKKVLDIFRENKISGSFLPFLDENLLESLGVSSLEQRKKMIECIQKLNQSRIDLMKVFNDPIHGHIEFHPLLIRIIDTPQFQRLRYIKQLGGG-YYVFPGASHNRFEHSLGVGYLAGCLVRALAEK-QPELQISERDMLCVQIAGLCHDLGHGPFSHMFDGRFIPLARPDIKWRHEQGSVEMFEHLVNSNELKLVMKNYGLVPEEDITFIKEQIMGPPVSPVKD-CLWPYKGRPAKKSFLYEIVANKRNGIDVDKWDYFARDCHHLGIQN--NFDYKRFIKFARICEVD-----DETRAHKVKHICTREKEVGNLYDMFHTRNCLHRRAYQHKIGNLIDIMITEAFLKADPHVEITGTEGKKFRISTAIHDMEAFSKLTDNIFLEILYSTDPQLSEARNILRNIECRNLYKYLGETQPK-REKIKKAEYDKLAQEVANAKPEIAPDVELKAEDFIVDVINMDYGMEDKNPIDNVHFYCKSDSRQAVTITKDQVSQLLPQKFAEQLIRVYYKKKDKKSLDAAGKHFIQWCALRDFTKPQDGDIIAPLITPLK--WNKKTS------------------SCIEEVSKVKTCLKF-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60710-1", "uniprot_id": "SAMH1_MOUSE", "id": "Q60710-1", "name": "Deoxynucleoside triphosphate triphosphohydrolase SAMHD1", "aln": "MDSLLGCGVSAAAREPVPRYLTSQPRVSEVAMQSAPLEQPAKRPRCDGSPRTPPSTPPATANLSADDDFQNTDLRTWEPEDVCSFLENRGFREKKVLDIFRDNKIAGSFLPFLDEDRLEDLGVSSLEERKKMIECIQQLSQSRIDLMKVFNDPIHGHIEFHPLLIRIIDTPQFQRLRYIKQLGGG-YYVFPGASHNRFEHSLGVGYLAGCLVRALAEK-QPELQISERDILCVQIAGLCHDLGHGPFSHMFDGRFIPRARPEKKWKHEQGSIEMFEHLVNSNELKLVMKNYGLVPEEDITFIKEQIMGPPITPVKD-SLWPYKGRPATKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQN--NFDYKRFIKFARICEVEYKVKEDKTYIRKVKHICSREKEVGNLYDMFHTRNCLHRRAYQHKISNLIDIMITDAFLKADPYVEITGTAGKKFRISTAIDDMEAFTKLTDNIFLEVLHSTDPQLSEAQSILRNIECRNLYKYLGETQPK-REKIRKEEYERLPQEVAKAKPEKAPDVELKAEDFIVDVINVDYGMEDKNPIDRVHFYCKSNSKQAVRINKEQVSQLLPEKFAEQLIRVYCKKKDGKSLDAAGKHFVQWCALRDFTKPQDGDIIAPLITPLK--WNNKTS------------------SCLQEVSKVKTCLKF-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y3Z3-1", "uniprot_id": "SAMH1_HUMAN", "id": "Q9Y3Z3-1", "name": "Deoxynucleoside triphosphate triphosphohydrolase SAMHD1", "aln": "-------------------------------MQRADSEQPSKRPRCDDSPRTPSNTPSAEADWSPGLE-LHPDYKTWGPEQVCSFLRRGGFEEPVLLKNIRENEITGALLPCLDESRFENLGVSSLGERKKLLSYIQRLVQIHVDTMKVINDPIHGHIELHPLLVRIIDTPQFQRLRYIKQLGGG-YYVFPGASHNRFEHSLGVGYLAGCLVHALGEK-QPELQISERDVLCVQIAGLCHDLGHGPFSHMFDGRFIPLARPEVKWTHEQGSVMMFEHLINSNGIKPVMEQYGLIPEEDICFIKEQIVGPLESPVED-SLWPYKGRPENKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQN--NFDYKRFIKFARVCEVD-----------NELRICARDKEVGNLYDMFHTRNSLHRRAYQHKVGNIIDTMITDAFLKADDYIEITGAGGKKYRISTAIDDMEAYTKLTDNIFLEILYSTDPKLKDAREILKQIEYRNLFKYVGETQPTGQIKIKREDYESLPKEVASAKPKVLLDVKLKAEDFIVDVINMDYGMQEKNPIDHVSFYCKTAPNRAIRITKNQVSQLLPEKFAEQLIRVYCKKVDRKSLYAARQYFVQWCADRNFTKPQDGDVIAPLITPQKKEWNDSTSVQ--------------NPTRLREASKSRVQLFKDDPM---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q502K2-1", "uniprot_id": "SAMH1_DANRE", "id": "Q502K2-1", "name": "Deoxynucleoside triphosphate triphosphohydrolase SAMHD1", "aln": "------------------------------------MENRIKRPRVDGECVKSIN---------------NGEFDRWDVEDTVAYLRGEGLQE--WAQIFKDNGITGAGLLCLTEAHLEKMGVSPLGARLHILHCLQKLSQISTEPMKVFNDPIHGHIELHPLLLHFIDTPQFQRLRHIKQLGGT-YLVFPGASHNRFEHSIGVGYLAGCLVKALNER-QPELFITKQDILCVQIAGLCHDLGHGPFSHMFDGMFIPKARPADKWKHEIASVQMFDHLVEVNGLEAVMLHHGMRLPEDLIFIKEQIAGPLESAVLDQSQWPYKGRPVEKSFLYEVVANKRNGIDVDKWDYFARDCYHLGIQN--NFDYQRFLRFARVCEVK-----------GRKHICTRDKEVGNLYDMFHTRNCLHRRAYQHKVGNIIETMITEAFLKADPHIQIQGSSGRIFTISSAIEDMEAYSKLTDHIFEQILYSSGPELSEARAILQNIICRRLYKCVGQTTSETNVDVSQEKLLDWAKELARSKP-TGTEGNLIAEDFVVSVIHMDYGMKEKNPINNVHFYCKNDPTKAIKIHKKQVSKLLPERFAEQLIRVYCKKTDDKSLEAAKKYFVQWCMDRNFTKPQDGDIIAPELTPLKQDWHAREDEDEEEEEKHRQNQTLPHHTPQRTGRNVKVDLFQARGETKL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VVY4-1", "uniprot_id": "Q9VVY4_DROME", "id": "Q9VVY4-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------MLIEDEVHGVIELSSHIQEIVEHPLFQRLKHVHQLGLLPWAIDKKADHKRYDHCLGAYKSAQDHLRAIERNSHYEPKLPDWCRQAVEIAALLHDIGHGPMSHAWE------LVTHHEFDHEENAMACVDKIFKDALNQELVSLRDDGGGRGVQLIKALILGSSEN-----LPFPMLG----HTYIFDIVHNRRCGLDVDKWDYLRRDNKRLKILSSAEMDFDDVFLQARISPDG-------------QRIEYRYADYHRVYRLFEARSLLHVKAYQYPLTCAMDVIFVSVVQRIAPELLSIRSKD------------PKWLELTDEYVLNVIE---------------------------------------------------------------KDPISRYVKEPHRLVEVPSND-------CSGSDIIRVNRVIPGPWELIKSARELAFFGNKRKKRPITRCVSPTIVNKCFKLE------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :::* :** **: . : .::: * ****::::*** : : *.*:*::*.:*. * ::*: .. : * :.. .*:**.* **:****:** :: . :: ** :: .:::.: : :: . ..: :** * *. . :* * :::::::* *:* *:*******: ** :* * . ::*:. .: **:. :* * : .:* :*.:*. ** :***: : :: ::.... : : : . : :***. . ::: :* : :: : : : . : : : : . : *.:* . *: . .. ::: * : ", "identical_positions": 77, "similar_positions": 137, "identity": "11.14%" }, { "cls_id": "homologset.agr.RGD:1308370", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4A081-1", "uniprot_id": "D4A081_RAT", "id": "D4A081-1", "name": "Histone-lysine N-methyltransferase SETDB1", "aln": "--MVLGVFKSQLSTGKQNSGESMSSLPGCMSLAAAPAAADSAEIAELQQAVVEELGISMEELRQFIDEELEKMDCIQQRKKQLAELETWVLQKESEVAYVDRLFDDASREVTNCESLVKDFYSKLGLQYHDSSSDDEA--SQPTEIIEIPDEDDD----VLSIDSGDA----------GSRTPKDQKLREAMAALRKSAQDVQKFMDAVNKKSSS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QDLHKGTLGQVSGELSKDGDLIVSMRILGKKRTKTWHKGTLIAIQTVGLGK-----KYKVKFDNKGKSLLSGN--HIAYDYHPPADKLFVGSRVVAKYK---------DGNQVWLY-AGIVAETPNVKNKLRFLIFFDDGYASYVTQSELYPICRPLKKTWEDIEDSSCRDFIEEYITAY-PNRPMVLLKSGQLIKTEWEGTWWKSRVEEVDGSLVRILFLDDK-RCEWIYRGSTRLEPMFSMKTSSASAMEKKQGGQLRTRPNMGAVRSKGPVVQYTQDLTSTG-IQFKPMEPLQPIVPPAP--LPMLPLSPQAGDSESLESQLAQSRKQVAKKSTSFRPGSVSSGHSSPTSPTLSENVPPGKIGMNQTYRSPSASVTSTPAPAAP------SGPPAPPGPLAPPGPPAPPAFHGMLERAPAEPSYRAPMEKLFYLPHVCSYTCLSRIRPMRNEQYRGKNPLLVPLLYDFRRMTARRRVNRKMGFHVIYKTPCGLCLRTMQEIERYLFETG-CDFLYLEMFCLDPYVLVDRKFQP----FKPFYYILDITYGKEDVPLSCVNEIDTTPPPQVAYSKERIPGKGVFINTGPEFLVGCDCKDGCRDKSKCACHQLTVQATACTPGGQINPSSGYQHKRLEECLPTGVYECNKRCKCDPNMCTNRLVQHGLQVRLQLFKTQNKGWGIRCLDDIAKGSFVCIYAGKILTDDFADKEGLEMGDEYFANLDHIESVENFKEGYESDVPSS-SDSSGVDMKDQEDGNSGSEDPEESNDDSSDDNFCKDEDFSTSSVWRSYATRRQTRGQKESELSEVTSKDSRAPDRGPPHVPITPSGSVGGCNPPSSEETPKNKVASWLSCNSVSEGGFADSDSRSSFKTSEGGDGRAGGGRGEAERASTSGLSFKDEGDSKQSKKEDPEDRNKMSVVTEGSQNHGHNP-PMKSEGLRRPASKISMLQSQRVVTSTQSNPDDILTLSSSTESEGESGTSRKPTTGQTSATAVDSDDIQTISSGSDGDDFEDKKNLSGPTKRQVAVKSTRGFALKSTHGIAIKSTNMASVDKGESAPVR-----------KNTRQFYDGEESCYIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIRAGTELTWDYNYEVGSVEGKELLCCCGAIECRGRLL------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88974-1", "uniprot_id": "SETB1_MOUSE", "id": "O88974-1", "name": "Histone-lysine N-methyltransferase SETDB1", "aln": "----------------------MSSLPGCMSLAAAPAAADSAEIAELQQAVVEELGISMEELRQYIDEELEKMDCIQQRKKQLAELETWVLQKESEVAYVDRLFDDASREVTNCESLVKDFYSKLGLQYHDSSSEDEA--SRPTEIIEIPDEDDD----VLSIDSGDA----------GSRTPKDQKLREAMAALRKSAQDVQKFMDAVNKKSSS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QDLHKGTLGQVSGELSKDGDLIVSMRILGKKRTKTWHKGTLIAIQTVGLGK-----KYKVKFDNKGKSLLSGN--HIAYDYHPPADKLFVGSRVVAKYK---------DGNQVWLY-AGIVAETPNVKNKLRFLIFFDDGYASYVTQSELYPICRPLKKTWEDIEDSSCRDFIEEYITAY-PNRPMVLLKSGQLIKTEWEGTWWKSRVEEVDGSLVRILFLDDK-RCEWIYRGSTRLEPMFSMKTSSASAMEKKQGGQLRTRPNMGAVRSKGPVVQYTQDLTGTG-IQFKPMEPLQPIAPPAP--LPIPPLSPQAADTD-LESQLAQSRKQVAKKSTSFRPGSVGSGHSSPTSSTLSENVSAGKLGINQTYRSPLASVTSTPASAAPPVPPVPPGPPTPPGPPAPPGPLAPPAFHGMLERAPAEPSYRAPMEKLFYLPHVCSYTCLSRIRPMRNEQYRGKNPLLVPLLYDFRRMTARRRVNRKMGFHVIYKTPCGLCLRTMQEIERYLFETG-CDFLFLEMFCLDPYVLVDRKFQP----FKPFYYILDITYGKEDVPLSCVNEIDTTPPPQVAYSKERIPGKGVFINTGPEFLVGCDCKDGCRDKSKCACHQLTIQATACTPGGQVNPNSGYQYKRLEECLPTGVYECNKRCNCDPNMCTNRLVQHGLQVRLQLFKTQNKGWGIRCLDDIAKGSFVCIYAGKILTDDFADKEGLEMGDEYFANLDHIESVENFKEGYESDVPTS-SDSSGVDMKDQEDGNSGSEDPEESNDDSSDDNFCKDEDFSTSSVWRSYATRRQTRGQKENELSEMTSKDSRPPDLGPPHVPIPSSVSVGGCNPPSSEETPKNKVASWLSCNSVSEGGFADSDSRSSFKTSEGGDGRAGGGRGEAERASTSGLSFKDEGDNKQPKKEDPENRNKMPVVTEGSQNHGHNP-PMKSEGLRRPASKMSVLQSQRVVTSTQSNPDDILTLSSSTESEGESGTSRKPTAGHTSATAVDSDDIQTISSGSDGDDFEDKKNLSGPTKRQVAVKSTRGFALKSTHGIAIKSTNMASVDKGESAPVR-----------KNTRQFYDGEESCYIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIRAGTELTWDYNYEVGSVEGKELLCCCGAIECRGRLL------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15047-1", "uniprot_id": "SETB1_HUMAN", "id": "Q15047-1", "name": "Histone-lysine N-methyltransferase SETDB1", "aln": "----------------------MSSLPGCIGLDAATATVESEEIAELQQAVVEELGISMEELRHFIDEELEKMDCVQQRKKQLAELETWVIQKESEVAHVDQLFDDASRAVTNCESLVKDFYSKLGLQYRDSSSEDES--SRPTEIIEIPDEDDD----VLSIDSGDA----------GSRTPKDQKLREAMAALRKSAQDVQKFMDAVNKKSSS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QDLHKGTLSQMSGELSKDGDLIVSMRILGKKRTKTWHKGTLIAIQTVGPGK-----KYKVKFDNKGKSLLSGN--HIAYDYHPPADKLYVGSRVVAKYK---------DGNQVWLY-AGIVAETPNVKNKLRFLIFFDDGYASYVTQSELYPICRPLKKTWEDIEDISCRDFIEEYVTAY-PNRPMVLLKSGQLIKTEWEGTWWKSRVEEVDGSLVRILFLDDK-RCEWIYRGSTRLEPMFSMKTSSASALEKKQG-QLRTRPNMGAVRSKGPVVQYTQDLTGTG-TQFKPVEPPQPTAPPAPPFPPAPPLSPQAGDSD-LESQLAQSRKQVAKKSTSFRPGSVGSGHSSPTSPALSENVSGGKPGINQTYRSPLGSTASAPA------------------PSALPAPPAPPVFHGMLERAPAEPSYRAPMEKLFYLPHVCSYTCLSRVRPMRNEQYRGKNPLLVPLLYDFRRMTARRRVNRKMGFHVIYKTPCGLCLRTMQEIERYLFETG-CDFLFLEMFCLDPYVLVDRKFQP----YKPFYYILDITYGKEDVPLSCVNEIDTTPPPQVAYSKERIPGKGVFINTGPEFLVGCDCKDGCRDKSKCACHQLTIQATACTPGGQINPNSGYQYKRLEECLPTGVYECNKRCKCDPNMCTNRLVQHGLQVRLQLFKTQNKGWGIRCLDDIAKGSFVCIYAGKILTDDFADKEGLEMGDEYFANLDHIESVENFKEGYESDAPCS-SDSSGVDLKDQEDGNSGTEDPEESNDDSSDDNFCKDEDFSTSSVWRSYATRRQTRGQKENGLSETTSKDSHPPDLGPPHIPVPPSIPVGGCNPPSSEETPKNKVASWLSCNSVSEGGFADSDSHSSFKTNEGGEGRAGGSRMEAEKASTSGLGIKDEGDIKQAKKEDTDDRNKMSVVTESSRNYGYNPSPVKPEGLRRPPSKTSMHQSRRLMASAQSNPDDVLTLSSSTESEGESGTSRKPTAGQTSATAVDSDDIQTISSGSEGDDFEDKKNMTGPMKRQVAVKSTRGFALKSTHGIAIKSTNMASVDKGESAPVR-----------KNTRQFYDGEESCYIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIRAGTELTWDYNYEVGSVEGKELLCCCGAIECRGRLL------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08BR4-1", "uniprot_id": "STB1B_DANRE", "id": "Q08BR4-1", "name": "Histone-lysine N-methyltransferase SETDB1-B", "aln": "------------------------------------------MEMELEPELEEELGVSLDELRKWIEEQVDSSEAVQKRKADLEQLQEWVEQREKEVADIDALCSNASESVVQCEALVKEVYSNMGLVYRESSSDDEGGKANPSEVIEIDDDDDDDVIAVGCLVPPKK----------SLTQAKDPALKEASAALQRTSQQVQNLAQTVNRTAQSGVTTPVKTGGPPGQGPLAVPAVFM----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SSAPRNTPTQPNPNIKQD-SIKINMTLLGKKRTKTWHRGTLVAIKQVGNNL-----KYKVRFENKGKSLLSGN--HVAFEYHPTLERLFVGARVVARYK---------DGNQVWLY-AGVVAEMPNSKNRMRFLIFFDDGYASYVGLPELYPICRPLKKTWEDIEDASCRDFIEEYITSY-PNRPMVLLKPGQIIKTEWEGTWWKSRVEEVDGSLVKMLFLDDK-RSEWIYRGSTRLEPMFNLKMNTANSQEKKMAGQQRQRPNMGALRTKGPVVQYTSDNSAAASTGGGAATPGTPTRPVAP--QPAGPPQPSRTESPSFKSQMAK--KSTGQLALQPRQGMPSDLQPKPIINALQTNTSR----LFLLQSGPVHTLTPITP---------------------APQTVQTAISTYTNERVPQEPSYQAPNDRLFYLTHNCSPECLKRIRPTRPNLHRGRNPLLTPLLYEFRRMTGRRRLNRKMSFHVIYKSPCGLSLRNMTEIQRYLFQTQ-CDFIFLEMFCLDPYVLVDRRFQP----QRPFYFIRDITSGREDIPLSCVNEIDNTPPPSVAYSKERIPEDGVYINTSADFLVGCDCTDGCRDKSKCSCHQLTLQATGCTPGGQINPNAGYHYKRLDECLPTGIYECNKRCRCNMQMCTNRLVQHGLQVRLQLFKTQNKGWGIRCLDDIAKGSFVCIYAGKILTDDFADKEGLEMGDEYFANLDHIESVENFKEGYESEAHCSDSEGSGVDMSR-------VKLPASSRHGKSNK---MEE--------RNSSTTGKSQDDSSEESDDEKDDDSNEDD------------------SDSSDDT------------FVKDTYYTTSSVWRSYTTR-----RQAKGLKEESQDSKDGMSVSAGEDRKPPHMPEETGKSKVASWLTNQ-------------------SSTSANQSVKVEGGIKTEKKDVMTLS-------------------------DSDDVQTISSGSD-DNKEREKKTQAVVKRQVAVKSTRGIALKS-HSMMVKSG-GGGAGGGGSGPSHGHGGGGGDNGPKNTRLFFDGEESCYIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIRAGTELTWDYNYEVGSVEGKELLCCCGSTECRGRLLQIIKTEWEGTWW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q1L8U8-1", "uniprot_id": "STB1A_DANRE", "id": "Q1L8U8-1", "name": "Histone-lysine N-methyltransferase SETDB1-A", "aln": "--------------------------------------------MSREKDDENLLRMTKDDLQRWIQAEVERNPHLMQRREQLAQVEEWVKQKERDSTCTRLLYSNACESVLECESVMKGLYALLGLDYRDEDSEEEGGGGQPHDVIQIADDEAERRGNVICNGEDDDNDDLVVIDLGATKETLEPMLEKVTVAIQKSSKLVQDLVQMVSKTSMGATSPLSTSSSDINRPSSSSTPEIVRPESVTPKLEITNSITIVKTESLSSVPKISSLFNSSEQCKSIADHDSYFKPTIKTEPEWTPLTPWEDSESSPFEKLIKTESQSTDVTPSVMTPNKQPELLSFQSTTKIKPEPQSTQANTELSSPPSNSKLLENHNSLSIAAIKNESQLKASVSEVDLLESDSEQSDNAATKTRFKPSEVTASSKLKSSGDHNSASASLNRTDPKVRPVTPSGTPPPSKSPPAVDNTASVETNQTDSELPTETPVEESTLPSNPKEAVIMSDAESTDKTEKPQTRKKSSKPSVTTTSPESRLTSSKSPPVTKTSSTQKETARAQSPSDSIDESADMEDSPDEPSNSPTESPTKTPDKTTRNDAPAKPSKAKKSSKHSSSESSKTLKEIKLKVGAAVLGKKRHNHWSRGTVQEVETEDDGN-----TYKVEFKKGKTIVLSAN--HVAAYKPPSLKDLYIGCRVVASAK---------SENGKSLYNAGVMVELPERKNRMRFLVFFDDGLATYLALPDLYFVCKQTKKVWREIKDESSRKQVKDYLQVY-PNPIAVVLRLGQETKAVRNGQFEDCTVLQLDGSLVQICYKNDK-QKEWIYKGSDKLEHILTIKN------RHKQHSHKKHHSPEGKTQSSQPKTLHSSKSASTS----------TSSANVSP--VSSDSVSPARVTRQSDKTKTSISPQKIMSPAFQPKVVLQKISLPSSISPAARVSNSNTNSSLISAKR------------------------------------PAPDEEEDEYFSEDEVEVLEQEQNKSVYLHQRCCPACLEEVRPHQVDIHHGKNPLLIPLLFKFRRMTARRRIDGKLFFHIFYRSPCGRSLCDMQEVQDYLFETR-CDFLFLEMFCMDPFVLVNRARPPSTTTGQPHLYLPDISEGKEVMPVPCVNEVDNTLAPNVTYTKDRVPARGVFINTSSDFMVGCDCTDGCRDRSKCACHKLTIEATSLCTGGPVDVSAGYTHKRLPTSLPTGVYECNPLCRCDPRMCSNRLVQHGMQLRLELFMTQHKGWGIRCKDDVPKGTFVCVFTGKIVNEDKMNEDDTMSGNEYLANLDFIEGVEKLKEGYESEAYCS---------------------------------------------------------DTEVESSKKTITMKTGP--------------------------------------LLKNSLYKEDSS------------SGEEPMEVDTAKDKVKVHDKPLGERKLPNKPHETP-----------------------------------------------------------------------------------------------KDTQKKISELRKNDGQESSGPKRCFAIKSFQRRVKPLESTEAQKEKTKTPKN-------------TRGLFNDEDACYIIDARQEGNLGRYINHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIKAGTELTWDYNYEVGSVEGKVLLCCCGSLRCTGRLL------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q32KD2-1", "uniprot_id": "SETB1_DROME", "id": "Q32KD2-1", "name": "Histone-lysine N-methyltransferase eggless", "aln": "MSGQPTAVDCLESSGSTVEDVQETPASREKSYGLPVRKGENSLESPAEQAAKDVEIEELTHSEAIAATGSTRKQCPYGGKAPDEPGKLADESEDRKGENTKAIASSPVLVAVDSDSSVELIESPVKFSSANESEKDPP---KPDAVNEAAAKEAEEMTDSSISSPTSESFPEKDEKTNKENEQEPPGMEVDQDVEESISRPAEEYKIENTLKGHKRISLTEIEEHKIVDKKDDVLEVELEKGTAPKAAEDEKLNALLSDGDVFYDKECVNCNCTKLHKQYVLANMATLNFYQVLRKSSKQQFLCMGCHDTAMDLYEEYAGQLMAKQPLLLKDFHQDHADFVALDSSDEEEEEKQPEKSDFSKNKLQLIEDELDDAIKNVLNKVDFTAQLSWSKTILQAKADHLERQFALADVELEKVQTTADKMHCALYN--------------------------------------------------------------------------------------------------------------------------------------------------------SCPVAHKHLPTLDIEPSDYVHEVPPPGEIVRPPIQLGETYYAVKNKAIASWVSIKVIEFTESTAINGNTMKSYKIRYLNTPYQMIKTVTAKHIAYFEPPPVRLTIGTRVIAYFDGTTLSRGKDKGVVQSAFYPGIIAEPLKQANRYRYLIFYDDGYTQYVPHRDVRLVCQASEKVWEDVHAAS-RDFIQKYVEKYSVDRPMVQCTRGQSMTTESNGTWLYARVIDIDCSLVLMQFEGDKNHTEWIYRGSLRLGPVF---------RETQNNMNSSSAQQLRVPRRTEPFIRYTKEMESSS--------------------KVNQQMRAFARKSSASAQNNALAAASSAATPAGGRTNAGGVSTSNSASAVRHLNNST-----------------------------------------------IYVDDENRPKGHVVYFTAKRNLPPKMYKCHECSPNCLFKIVHR----LDSYSPLAKPLLSGWERLVMR----QKTKKSVVYKGPCGKSLRSLAEVHRYLRATENVLNVDNFDFTPDLKCLAEYSIDP------SIVKDTDISKGQEKMAIPLVNYYDNTLPPPCTYAKQRIPTEGVHLNLDEEFLLCCDCEDDCSDKSKCACWQLTVAGVRYCNPKKPIEEIGYQYKRLHEHVPTGIYECNSRCKCK-KNCLNRVVQFSLEMKLQVFKTSNRGWGLRCVNDIPKGAFICIYAGHLLTETMANEGGQDAGDEYFADLDYIEVAEQLKEGYESEVDHS----------------------------------------------------------------------------------------------------------------------------------------------DPDAEEDNGGPDAEDDDDFRP-------------------------------------------------------------------------------------------------------NYHYQRKIKRSSRSGSTQNSSTQSSELDSQERAVINFNPNADLDETVRENSV--------------RRLFGKDEAPYIMDAKTTGNLGRYFNHSCSPNLFVQNVFVDTHDLRFPWVAFFSAAHIRSGTELTWNYNYEVGVVPGKVLYCQCGAPNCRLRLL------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . . : : ..: . : ... . :.:: :: . : : : :....: .* : : .: : . :. . . :: .:. . .. . . .: : :* * .: . .**:.: : ::. : *. * :* **:* . . : .*::.* : *: *:*:*:*** : *: :: :*: :*.*.::. * *. ::.*: * : * ** .: :* : . * ::* *** : : .** : ****:** :* :: . : : : . * ::.. .:. . : : . . : ... . . . . .* : *. ** .: . .** *** :.*:. * * :.*: *** .* : *:. ** * : * * *.: * . **: *:* :.:. ** *.* .* :*:*:*:* **.:* . :*:: *** *.* *:***:* :**: .. . ** :*** :***:**** *.*. . * **:**..::::*::* *.::***:** :*:.**:*:*:::*:::.: :: . *:**:*:**.** .*::******:. * .. . : : . . . . ..: :.* . * ::. ::: **:**: ******:****************************:: :*::******:****** * ** * * **: .* *** ", "identical_positions": 214, "similar_positions": 265, "identity": "12.02%" }, { "cls_id": "homologset.agr.RGD:1308371", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "B2RZD2-1", "uniprot_id": "T126B_RAT", "id": "B2RZD2-1", "name": "Complex I assembly factor TMEM126B, mitochondrial", "aln": "-MASERPTGSESGDAGVVLEGNREASQDIKMALYKHGRLIPSLGDAKFGRPMIAEILEKKFESYRN--DQTLNIRGTLFFGVSSSLSGVMANLVFRYSFKVK-YEALRTYASLTTLPFVATAVTYKLFVTDALQSGNI-SQESCVLRS-SLIGVACGVSYPSALAFYKNGRLAVKYHTVPVP----PKGRVMLHWLLLCQTGMKAMAVPLLFQIIFGVFNG----LYHYAVCEKAYARIVPDD----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D1R1-1", "uniprot_id": "T126B_MOUSE", "id": "Q9D1R1-1", "name": "Complex I assembly factor TMEM126B, mitochondrial", "aln": "MAASQRPSWSESKVAGVVQEGNREAPQDIKMALYKHGQLIPSLGDAKFRSPIISEIIEKKFEHYRN--DKTLNIHGTLVFGTSSSLSGIMANLVFRNSFKVK-YEALKTYASLTTLPVLATIVSYKLFVTDALQSGDI-SKESCVLRS-ALIGMACGVSYPSALAFYKNGRLAVKYQTVPLP----PKGRVMLHWLLLCQTGMKAMAIPLFFQIVMGAFTG----LHHYNICEKPRARLVPDD----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IUX1-1", "uniprot_id": "T126B_HUMAN", "id": "Q8IUX1-1", "name": "Complex I assembly factor TMEM126B, mitochondrial", "aln": "MVVFGYEAGTKPRDSGVVPVGTEEAPKVFKMAASMHGQPSPSLEDAKLRRPMVIEIIEKNFDYLRK--EMTQNIYQMATFGTTAGFSGIFSNFLFRRCFKVK-HDALKTYASLATLPFLSTVVTDKLFVIDALYSDNI-SKENCVFRS-SLIGIVCGVFYPSSLAFTKNGRLATKYHTVPLP----PKGRVLIHWMTLCQTQMKLMAIPLVFQIMFGILNG----LYHYAVFEETLEKTIHEE----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8QM83-1", "uniprot_id": "A0A2R8QM83_DANRE", "id": "A0A2R8QM83-1", "name": "", "aln": "-----------------------MTDNSMTMRDASQG-----LTSSRMR---IIEMLNKKFEKLPES-DRKMLSRGPLYLAANAGIAGMVANSFYRRVLHVT-QGLFTSSLPMAVLPFVTTAALYTATVTTPLLSGDL-NCPTCALIRGALVGVVGGGIYPILLALPVNAGLAARYNSAPMP----EKGNIIRFWTNLSKPVVKKMSFVLVLQCVIGTFLS----SRHFEIYLKMLRMPDSDSEQLNG-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VLM7-1", "uniprot_id": "T126_DROME", "id": "Q9VLM7-1", "name": "Transmembrane protein 126", "aln": "------------------------------MALSRAKPDELPRDAVVITEDQALKYQWKIITSWDKIGEVWSLRYTPGILSALAAGTGAYINNHYRTKLRLGGHGRLSTYLPIVAVPAIFTMLAHKFFIQRPILLNPLGECPVCIQMRSAAFQTSLGIVYPTILAPFAAFLFATRCYTYRIPSITENPREVFLLWRKFTRPIVPALGTLIGLQALLTMFLTGQEDKQNFKLMLRMREIEHQVEEEHLPQRMDF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : : * : : : :.. :. :* * :* ::: : : .:..:* : * . : .: . : . * : . * ** ** :*.: : :* .:: * : :. : :. : :* :: : :: : . . ", "identical_positions": 17, "similar_positions": 56, "identity": "6.72%" }, { "cls_id": "homologset.agr.RGD:1308372", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BFY9-1", "uniprot_id": "TNPO1_MOUSE", "id": "Q8BFY9-1", "name": "Transportin-1", "aln": "MVWDRQTKMEYEWKPDEQGLQQILQLLKESQSPDTTIQRTVQQKLEQLNQYPDFNNYLIFVLTKLKSEDEP-----------TRSLSGLILKNNVKAHFQNFPN--GVTDFIKSECLNNIGDSSP-LIRATVGILITTIASKGELQN--WPDLLPKLCSLLDSEDYNTCEGAFGALQKICEDSAEILDSDVL--DRPLNIMIPKFLQFFKHS--SPKIRSHAVACVNQFIISRTQALMLHIDSFIENLFALA-GDEEAEVRKNVCRALVMLLEVRMDRLLPHMHNIVEYMLQRTQDQ-DENVALEACEFWLTLAEQP-ICKDVLVRHLPKLIPVLVNGMKYSDIDIILLKGDVEEDETIPDSEQDIRPRFHRSRTVAQQHEE------DGIEEEDDDDDEIDDDDTISDWNLRKCSAAALDVLANVYRDELLPHILPLLKELLFHHEWVVKESGILVLGAIAEGCMQGMIPYLPELIPHLIQCLSDKKALVRSITCWTLSRYAHWVVSQPPDTYLKPLMTELLKRILDSNKRVQEAACSAFATLEEEACTELVP--YLAYILDTLVFAFSKYQHKNLLILYDAIGTLADSVGHHLNKPEYIQMLMPPLIQKWNMLKDEDKDLFPLLECLSSVATALQSGFLPYCEPVYQRCVNLVQKTLAQAMLNNAQPEQYEAPDKDFMIVALDLLSGLAEGLGGNIEQLVARS-----NILTLMYQCMQDKMPEVRQSSFALLGDLTKACFQHVKP-CIADFMPILG----TNLNPEFISVCNNATWAIGEISIQMGIEMQPYIPMVLHQLVEIINRPNTPKTLLENTAITIGRLGYVCPQEVAP---MLQQFIRPWCTSLRNIRDNEEKDSAFRGICTMISVNPSGVIQDFIFFCDAVASWINPKDD--LRDMFCKILHGFKNQVGDENWRRFSDQFPLPLKERLAAFYGV--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92973-1", "uniprot_id": "TNPO1_HUMAN", "id": "Q92973-1", "name": "Transportin-1", "aln": "MVWDRQTKMEYEWKPDEQGLQQILQLLKESQSPDTTIQRTVQQKLEQLNQYPDFNNYLIFVLTKLKSEDEP-----------TRSLSGLILKNNVKAHFQNFPN--GVTDFIKSECLNNIGDSSP-LIRATVGILITTIASKGELQN--WPDLLPKLCSLLDSEDYNTCEGAFGALQKICEDSAEILDSDVL--DRPLNIMIPKFLQFFKHS--SPKIRSHAVACVNQFIISRTQALMLHIDSFIENLFALA-GDEEPEVRKNVCRALVMLLEVRMDRLLPHMHNIVEYMLQRTQDQ-DENVALEACEFWLTLAEQP-ICKDVLVRHLPKLIPVLVNGMKYSDIDIILLKGDVEEDETIPDSEQDIRPRFHRSRTVAQQHDE------DGIEEEDDDDDEIDDDDTISDWNLRKCSAAALDVLANVYRDELLPHILPLLKELLFHHEWVVKESGILVLGAIAEGCMQGMIPYLPELIPHLIQCLSDKKALVRSITCWTLSRYAHWVVSQPPDTYLKPLMTELLKRILDSNKRVQEAACSAFATLEEEACTELVP--YLAYILDTLVFAFSKYQHKNLLILYDAIGTLADSVGHHLNKPEYIQMLMPPLIQKWNMLKDEDKDLFPLLECLSSVATALQSGFLPYCEPVYQRCVNLVQKTLAQAMLNNAQPDQYEAPDKDFMIVALDLLSGLAEGLGGNIEQLVARS-----NILTLMYQCMQDKMPEVRQSSFALLGDLTKACFQHVKP-CIADFMPILG----TNLNPEFISVCNNATWAIGEISIQMGIEMQPYIPMVLHQLVEIINRPNTPKTLLENTAITIGRLGYVCPQEVAP---MLQQFIRPWCTSLRNIRDNEEKDSAFRGICTMISVNPSGVIQDFIFFCDAVASWINPKDD--LRDMFCKILHGFKNQVGDENWRRFSDQFPLPLKERLAAFYGV--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6AG33-1", "uniprot_id": "A0A8I6AG33_RAT", "id": "A0A8I6AG33-1", "name": "Transportin-1", "aln": "--------MEYEWKPDEQGLQQILQLLKESQSPDTTIQRTVQQKLEQLNQYPDFNNYLIFVLTKLKSEDEP-----------TRSLSGLILKNNVKAHFQNFPN--GVTDFIKSECLNNIGDSSP-LIRATVGILITTIASKGELQN--WPDLLPKLCSLLDSEDYNTCEGAFGALQKICEDSAEILDSDVL--DRPLNIMIPKFLQFFKHS--SPKIRSHAVACVNQFIISRTQALMLHIDSFIENLFALA-GDEEAEVRKNVCRALVMLLEVRMDRLLPHMHNIVEYMLQRTQDQ-DENVALEACEFWLTLAEQP-ICKDVLVRHLPKLIPVLVNGMKYSDIDIILLKGDVEEDEAIPDSEQDIRPRFHRSRTVAQQHEE------DGIEEDDDDDDEIDDDDTISDWNLRKCSAAALDVLANVYRDELLPHILPLLKELLFHHEWVVKESGILVLGAIAEGCMQGMIPYLPELIPHLIQCLSDKKALVRSITCWTLSRYAHWVVSQPPDTYLKPLMTELLKRILDSNKRVQEAACSAFATLEEEACTELVP--YLAYILDTLVFAFSKYQHKNLLILYDAIGTLADSVGHHLNKPEYIQMLMPPLIQKWNMLKDEDKDLFPLLECLSSVATALQSGFLPYCEPVYQRCVNLVQKTLAQAMLNNAQPEQYEAPDKDFMIVALDLLSGLAEGLGGNIEQLVARS-----NILTLMYQCMQDKMPEVRQSSFALLGDLTKACFQHVKP-CIADFMPILG----TNLNPEFISVCNNATWAIGEISIQMGIEMQPYIPMVLHQLVEIINRPNTPKTLLENTAITIGRLGYVCPQEVAP---MLQQFIRPWCTSLRNIRDNEEKDSAFRGICTMISVNPSGVIQDFIFFCDAVASWINPKDD--LRDMFCKILHGFKNQVGDENWRRFSDQFPLPLKERLAAFYGV--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8N7TD97-1", "uniprot_id": "A0A8N7TD97_DANRE", "id": "A0A8N7TD97-1", "name": "Transportin-1", "aln": "--------MECQWKPDEQGLQQILQLLKESQSPDTSTQRSVQQKLEQLNQYPDFNNYLIFVLTKLKTEDEP-----------TRSLSGLILKNNVKAHYQNFPN--GVSDFIKNECLQSIGDSSP-LIRATVGILITTIASKGELQN--WPELLPKLCLLLDSEDYNTCEGAFGALQKICEDSAEILDSDML--ERPLNVMIPKFLQFFKHS--SPKIRSHAIACVNQFIISRTQALMLHIDPFIENLFALA-GDEEPEVRKNVCRALVMLLEVRLDRLLPHMHNIIEYMLQRTQDQ-DENVALEACEFWLTLAEQP-VCKEVLCGHLPKLTPVLVNGMKYSEIDIILLKGDVEEDEAIPDNEQDIRPRFHRSRTVAQQHEGG-----DSIEEDDDDEDDLDDDETISDWNLRKCSAAALDVLANVFRDDLLLHILPLLKELLFHPEWLIKESGILVLGAIAEGCMQGMIPYLPELIPHLVLCLSDKKALVRSITCWTLSRYAHWVVSQPPDTYLKPLMTELLKRILDSNKRVQEAACSAFATLEEEACTELVP--YLAYILDTLVFAFSKYQHKNLLILYDAIGTLADSVGHHLNKPEYIQMLMPPLIQKWNQLKDEDKDLFPLLECLSSVATALQSGFLPYCEPVYQRCVNLVQKTLAQAVLHQNQPEYYEAPDKDFMIVALDLLSGLAEGLGGNIEQLVARS-----NILTLMYQCMQDKMPEVRQSSFALLGDLTKASFQHVKP-CIANFMPILG----TNLNPELISVCNNATWAIGEISIQMGSEMQPYVPLVLQQLVEIINRPNTPKTLLENTAITIGRLGYVCPQEVAP---MLQQFIRPWCTSLRNIRDNEEKDSAFRGICTMITVNPGGVVQDFIFFCDAVASWMNPKDD--LREMFYKILHGFKNQVGDENWRRFSDQFPPPLKERLAAFYGV--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VRV8-1", "uniprot_id": "Q9VRV8_DROME", "id": "Q9VRV8-1", "name": "Transportin-1", "aln": "----------MTWEPQGEGLQQIIAILKESQSPDTATQMAVQMKLEEFNRYPDFNNYLIYVLTKLKTEDEP-----------TRSLSGLILKNNIRMHGTTLQP--EIVEYIKHECLQAVGDASP-LIRATVGILITTIASNGGLHN--WPQLLPSLCEMLDNQDYNVCEGAFSALQKICEDSAEILDSAAL--NRPLNIMIPKFLEYFKHS--SPKIRSHAIACINQFIINRSQALMLNIDSFIENLFHLS-SDEDHEVRKNVCHGLVMLLEVRMDRLMPHMSQIIEYMLLRTQDT-DEGVALEASEFWLSLAEQS-ICKDVLAPYLAQLAPVLVRGMRYSEVDIILLKGNVEEDDMVPDREEDIRPRFHKSRAHTIRSTQEGGAGATGDDDDDEFEDGMDDDSSLSEWNLRKCSAAALDVLANVFREDCLPVVLPILKETLFHQEWVIKESGVLALGAIAEGCMQGMIQHLPELIPYLISCLSDKKALVRSITCWTLSRYANWVVNQPHDQYLKPLMEELLKRILDSNKRVQEAACSAFATLEEEACTELVP--YLEYILKTLVFAFSKYQHKNLLILYDAVGTLADSVGHHLNKPQYIDILMPPLIDKWNLLKDDDKDLFPLLECLSSIATALQSGFLPYCDPVYRRCISLIEQTINQEMLCK-QNQTYDHPDKERMIVALDLLSGLAEGLDRHIETLVANS-----NIMHLLYQCMQDVLPEVRQSSFALLGDLTKACFPHVHP-FMADFFPILG----QNLNPDFISVCNNATWAIGEICMKLGEETKQYIRLVLSDLFIIINRPNTPKTLLENTAITIGRLGYVCPVEVAP---YLPEFVRQWCTSLRHIRDNDEKDSAFRGMCHMITVNPAGVVADFIFFCDAIASWVNPPED--LHQMIQKILHGFKTQVGEENWRRFVEQFPPTLAERLTTMYNI--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VRV9-1", "uniprot_id": "Q9VRV9_DROME", "id": "Q9VRV9-1", "name": "", "aln": "----------MAWTPRDEGLQQLLPILKDSQSPGKATQLAVQ-----------------------ETENEA-----------TRSMSGLILKNNIRMHDITLQP--EHLEYIKHQCLQAVGDSSP-EIRGTVGILITTIASNIGLHN--WPQLLPSLCEMLDNQDYNVCEGAFSALQKICEDSAGILE------NMPLNTMIPKFLEYFKHS--SPKIRSHAIACINQFIINRSQALMLNIDSLIQNLLDVP-SDNDPAVRMNVCHALVGLVGVRIDLMMPHMSQIIELILLRSQDA-DENVALQATEFWLSLGKQR-NCRDILSPILSQLVPVLVSRTQYTETDIILLKGDVGEDDKEPDRQQDISPRFHMSRVHGIS---------------NELDENSDDDMWDSALNLRKCSACALDIISKIFGDVCLPLMLPILKEALFHQEWVIKESGVMALGAIAEGCMQGLIPHLPELIPYLITCLSDKKPLVRSITCWTFMRFPKWVLNQPHDKYLEPLIEELLKCILDSNKRVQEAACSAFVALEEEACTQLVP--YLENMLKTFVLAFSKYHQRNLLIMYDVVGLLAESVGHHLNKPQYIDILMPPLMDKWNLVKDDDKDIIYLLECLSSIATALQSSFLPYCDSVYRKGISIIEETINQDMMCK-QSQSTDYPDKERMVIALDLVSGLIEGLQSLIEPLVANS-----KLLQLLCQCMGDVMPEVRQSSFALLGDLSGACFSQVYP-YTAHFILILV----QNLNPSVVGVCNNAVWAIGQICVKLGEETKPYVRLLLSELMILMNRQDIPKNLSRNAAITLGRLGNACPDEVAP---YLPEFLRQWCLLLRYAYDHDEKYLSFMGMCHMIRENPGGVVPDFLFFCDAIASWDNPPQD--LRQMIRRIIEGFKNQTGAENWLIFLGKFPQPLACRLIELYDIEY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38217-1", "uniprot_id": "IMB2_YEAST", "id": "P38217-1", "name": "Importin subunit beta-2", "aln": "--------MASTWKPAEDYVLQLATLLQNCMSPNPEIRNNAMEAMENFQLQPEFLNYLCYILIEGESDDVLKQHYSLQDLQNNRATAGMLLKNSMLGGNNLIKSNSHDLGYVKSNIIHGLYNSNNNLVSNVTGIVITTLFSTYYRQHRDDPTGLQMLYQLLELTS-NGNEPSIKALSKIMEDSAQFFQLEWSGNTKPMEALLDSFFRFISNPNFSPVIRSESVKCINTVIPLQTQSFIVRLDKFLEIIFQLAQNDENDLVRAQICISFSFLLEFRPDKLVSHLDGIVQFMLHLITTVNEEKVAIEACEFLHAFATSPNIPEHILQPYVKDIVPILLSKMVYNEESIVLLEASNDDDAFLEDKDEDIKPIAPRIVKKKEAGNGED----ADDNEDDDDDDDDEDGDVDTQWNLRKCSAATLDVMTNILPHQVMDIAFPFLREHLGSDRWFIREATILALGAMAEGGMKYFNDGLPALIPFLVEQLNDKWAPVRKMTCWTLSRFSPWILQD-HTEFLIPVLEPIINTLMDKKKDVQEAAISSVAVFIENADSELVETLFYSQLLTSFDKCLKYYKKKNLIILYDAIGRFAEKCALDET---AMQIILPPLIEKWALLSDSDKELWPLLECLSCVASSLGERFMPMAPEVYNRAFRILCHCVELEAKSH-QDPTIVVPEKDFIITSLDLIDGLVQGLGAHSQDLLFPQGTKDLTILKIMLECLQDPVHEVRQSCFALLGDIVYFFNSELVIGNLEDFLKLIGTEIMHNDDSDGTPAVINAIWALGLISERIDLNTYIIDMSRIILDLFTTNTQIVDSSVMENLSVTIGKMGLTHPEVFSSGAFANDSNWNKWCLSVNALDDVEEKSSAYMGFLKIINLTSTEVTMSNDTIHKIVTGLSSNVEANVFAQEIYTFLMNHSAQISAINFTPDEISFLQQFTS----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * : : *: :*::. **. : . :::: .*: :*::***.: : ::* : :: : ::. : ..**:***: *. :: * * * :*: . * * :: **.** **** ::: *:: :: .*:.::.:. ** ***.:: *:* .* ::*::::.:* ::: :: :. .*:: ** ::* .: *: .* * ::.*: *:: :* :* **::* ** ::. . ..:* : .: *:*: *.: .*:**:.. :* * ::** * :: :: :*. : *******.:**::::: . : :*:*:* * .*.::*: ::.***:*** *: : ** ***.*: *.** . **.:****: *:. *::.: :* *:: ::: ::*.:* ***** *:...: *:* ::** : :* :: .:. *:::**:*:**.:* :*:. . . . :::::***::** :.*.**:: ******.:*::* . *:* . **.: . :: . : : * *:*: :: :***:.** :** : *: . .:: :: :*: * : *****.******: .: .*: :: * :.. . ** **:* *. ::. : : . * ..: .* ::*:*::* . * .:. . . ** :. * :** :: *: :* .. * . : . ::. . : : : : :: ... * . *: .* : ", "identical_positions": 204, "similar_positions": 312, "identity": "21.56%" }, { "cls_id": "homologset.agr.RGD:1308373", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5M7A7-1", "uniprot_id": "CNRP1_RAT", "id": "Q5M7A7-1", "name": "CB1 cannabinoid receptor-interacting protein 1", "aln": "MGDLPGIVRLSIALRIQPNDGPVFFKVDGQRFGQNRTIKLLTGSSYKVEVKIKPTTLQVENISIGGVLVPLELKCKEPDGERVVYTGIYDTEGVAPTKSGERQPIQITMPFTDIGTFETVWQVKFYNYHKRDHCQWGSPFSVIEYECKPNETRSLMWVNKESFL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5M8N0-1", "uniprot_id": "CNRP1_MOUSE", "id": "Q5M8N0-1", "name": "CB1 cannabinoid receptor-interacting protein 1", "aln": "MGDLPGLVRLSIALRIQPNDGPVFFKVDGQRFGQNRTIKLLTGSSYKVEVKIKPTTLQVENISIGGVLVPLELKGKEPDGERVVYTGIYDTEGVAPTKSGERQPIQITMPFTDIGTFETVWQVKFYNYHKRDHCQWGSPFSVIEYECKPNETRSLMWVNKESFL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96F85-1", "uniprot_id": "CNRP1_HUMAN", "id": "Q96F85-1", "name": "CB1 cannabinoid receptor-interacting protein 1", "aln": "MGDLPGLVRLSIALRIQPNDGPVFYKVDGQRFGQNRTIKLLTGSSYKVEVKIKPSTLQVENISIGGVLVPLELKSKEPDGDRVVYTGTYDTEGVTPTKSGERQPIQITMPFTDIGTFETVWQVKFYNYHKRDHCQWGSPFSVIEYECKPNETRSLMWVNKESFL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******:*****************:*****************************:******************* *****:****** ******:*********************************************************************", "identical_positions": 157, "similar_positions": 5, "identity": "95.73%" }, { "cls_id": "homologset.agr.RGD:1308374", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R104-1", "uniprot_id": "SIR3_MOUSE", "id": "Q8R104-1", "name": "NAD-dependent protein deacetylase sirtuin-3", "aln": "---------MALDPLGAVVLQSIMALSGR--------LALAA-----------------------------------------------LRLWGPGGGRRPISLCVGASGGFGGGGSSEK-KFSLQDVAELLRTRACSRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDIPYPEAIFELGFFFHNPKPFFMLAKELYPGHYRPNVTHYFLRLLHDKELLLRLYTQNIDGLERASGIPASKLVEAHGTFVTATCTVCRRSFPGEDIWADVMADRVP---RCPVCTGVVKPDIVFFGEQLPARF--------------LLHMADFALADLLLILGTSLEVEPFASLSEAVQKSVPRLLINRDLVGPFVLSPRRKDVVQLGDVVHGVERLVDLLGWTQELLDLMQRERGKLDGQDR------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5XWT5-1", "uniprot_id": "A0A8I5XWT5_RAT", "id": "A0A8I5XWT5-1", "name": "", "aln": "----MRSPDLAPQPISQSLTDGEAANTRHKPTLRHIGLTFRG-----------------------------------------------LAWEPITGGRRPISLSVGASGGFGCGGHSEK-KLSLQDVAELLRTRACSRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDIPYPEAIFELGFFFHNPKPFFTLAKELYPGHYRPNVAHYFLRLLHDKELLLRLYTQNIDGLERASGIPASKLVEAHGSFVSATCTVCRRSFPGEDIRADVMADRVP---RCPVCTGVVKPDIVFFGEQLPARF--------------LLHVADFALADLLLILGTSLEVEPFASLSESVQKSVPRLLINRDLVGSFALSPRRKDVVQLGDVVQGVERLVDLLGWTQELQDLIQRENGKLDGQDG------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NTG7-1", "uniprot_id": "SIR3_HUMAN", "id": "Q9NTG7-1", "name": "NAD-dependent protein deacetylase sirtuin-3, mitochondrial", "aln": "MAFWGWRAAAALRLWGRVVERVEAGGGVGPFQACGCRLVLGGRDDVSAGLRGSHGARGEPLDPARPLQRPPRPEVPRAFRRQPRAAAPSFFFSSIKGGRRSISFSVGASSVVGSGGSSDKGKLSLQDVAELIRARACQRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDLPYPEAIFELPFFFHNPKPFFTLAKELYPGNYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFASATCTVCQRPFPGEDIRADVMADRVP---RCPVCTGVVKPDIVFFGEPLPQRF--------------LLHVVDFPMADLLLILGTSLEVEPFASLTEAVRSSVPRLLINRDLVGPLAWHPRSRDVAQLGDVVHGVESLVELLGWTEEMRDLVQRETGKLDGPDK------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P53686-1", "uniprot_id": "HST2_YEAST", "id": "P53686-1", "name": "NAD-dependent protein deacetylase HST2", "aln": "-----------------------------------------------------------------------------------------------------MSVSTAST------------EMSVRKIAAHMKSNPNAKVIFMVGAGISTSCGIPDFRSPGTGLYHNLARLKLPYPEAVFDVDFFQSDPLPFYTLAKELYPGNFRPSKFHYLLKLFQDKDVLKRVYTQNIDTLERQAGVKDDLIIEAHGSFAHCHCIGCGKVYPPQVFKSKLAEHPIKDFVKCDVCGELVKPAIVFFGEDLPDSFSETWLNDSEWLREKITTSGKHPQQPLVIVVGTSLAVYPFASLPEEIPRKVKRVLCNLETVGDFKANKRPTDLIVHQYSDEFAEQLVEELGWQEDFEKILTAQGGMGDNSKEQLLEIVHDLENLSLDQSEHESADKKDKKLQRLNGHDSDEDGASNSSSSQKAAKE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*....:: ::*::.:* :::.. :*:.********..*********:*** ** : .:*****:*:: ** :* **: ********:::*. **:*:*::** :* *:****** *** :*: . ::****:*. . * * : :* : : :.: . : :* ** :*** ****** ** * : ... *::::**** * *****.* : .* *:* * : ** : * *: . .* **: *** ::: .:: : * *. . ", "identical_positions": 115, "similar_positions": 88, "identity": "24.47%" }, { "cls_id": "homologset.agr.RGD:1308376", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q4KLN5-1", "uniprot_id": "PLAT5_RAT", "id": "Q4KLN5-1", "name": "Phospholipase A and acyltransferase 5", "aln": "MIPGHRGPWSAPLCRRLVPAGHSGMGLSPAASGEYGIRLFRVPWPSRPKQISRTASTESSDTQ--------PTNDSASSQ----------ALVVQFLPKLPKQDRGLEQARSLRQGQKPEINLELIPSKKRTEMIPSSDSEIEGNLKNQAAESNQKPRPGDLIEIFRIGYEHWAIYVEDDCVVHLAPPSE-FEAGSITSIFSNRAVVKYSRLQDVLHGCSWKINNKLDGTYLPLPVDKIIQRTKNMINKIVQYSLIEGNCEHFVNDLRYGVPRSQQVEHVLVEGAKAAGAVLSAVVDSIRPKPITA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CPX5-1", "uniprot_id": "PLAT5_MOUSE", "id": "Q9CPX5-1", "name": "Phospholipase A and acyltransferase 5", "aln": "------------------------MGLSPAASGEFGIRLSRVPWP-RPTQISKTSSTESSDTQSATGQSTVPHSDSASSQ----------ALLVQFLPKQLKQDRRLEQARSFQQGEKPETSLELTPSKKRTELIPTSNSEIESTQKNQAVEGNPRPRPGDLIEIFRIGYEHWAIYVEDDCVVHLAPPSE-FEAGSITSIFSNRAVVKYSRLEDVLHGCSWKINNKLDGTYLPLPVDKIMQRTKNMINKIVQYSLIEGNCEHFVNDLRYGVPRSQQVEHALVEGAKAAGAVLSAVVDSIRPKPITA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96KN8-1", "uniprot_id": "PLAT5_HUMAN", "id": "Q96KN8-1", "name": "Phospholipase A and acyltransferase 5", "aln": "------------------------MGLSPGAEGEYALRLPRIPPP-LPKPASRTASTGPKDQPPALRRSAVPHSGLNSISPLELEESVGFAALVQLPAKQPPPG-TLEQGRSIQQGEKAVVSLETTPSQK-ADWSSIPKPENEGKLIKQAAEGKPRPRPGDLIEIFRIGYEHWAIYVEDDCVVHLAPPSEEFEVGSITSIFSNRAVVKYSRLEDVLHGCSWKVNNKLDGTYLPLPVDKIIQRTKKMVNKIVQYSLIEGNCEHFVNGLRYGVPRSQQVEHALMEGAKAAGAVISAVVDSIKPKPITA", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *****.*.**:.:** *:* * *. *:*:** ..* * .. * . * :**: .* . ***.**::**:*. .** **:* :: . ...* *.. :**.*.: :********************************** **.******************:*********:****************:****:*:******************.*************.*:*********:*******:******", "identical_positions": 181, "similar_positions": 49, "identity": "59.15%" }, { "cls_id": "homologset.agr.RGD:1308377", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "B2RYH9-1", "uniprot_id": "S71A2_RAT", "id": "B2RYH9-1", "name": "Solute carrier family 71 member 2", "aln": "MSTDGESPEEPGWKAVASPKASAMPEKRGSAQAASSSWLQGFGQPSVYHAAFVIFFEFFAWGLLTTPMLTVLHETFPQHTFLMNGLIQGVKGLLSFLSAPLIGALSDVWGRKPFLLGTVFFTCFPIPLMRISPWWYFGMISVSGVFSVTFSVIFAYVADFTQEHERSTAYGWVSATFAASLVSSPAIGTYLSSNYGDSLVVLVATVVALLDICFILVAVPESLPEKIRPASWGA-------------------------------------------------------------------------QISWKQADPFASLKKVGKDSTVLLICITVFLSYLPEAGQYSSFFLYLRQVIGFGSVKIVAFIAMVGILSILAQTVFLSKLMRSLGNKNTVLLGLGFQILQLAWYGFGAQAWMMWAAGTVAAMSSITFPAVSALISRNAESDQQGVAQGIITGIRGLCNGLGPALYGFIFYLFHVELNELGPKLDS---DNDPLQGAFIPGPPFLFGACIVLMSFLVALFIP-------EYRKTGGVQKHNNSISGSLSTPPERGSDEDIEPLLQDSNIWELS-SEEPGNQCTEL----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CIA9-1", "uniprot_id": "S71A2_MOUSE", "id": "Q8CIA9-1", "name": "Solute carrier family 71 member 2", "aln": "MSTDGESPEEPRWKAVASPKASTMPEKRGSAQAASGSWLQGFGHPSVYHAAFVIFLEFFAWGLLTTPMLTVLHETFPQHTFLMNGLIQGVKGLLSFLSAPLIGALSDVWGRKPFLLGTVFFTCFPIPLMRINPWWYFGMISVSGVFSVTFSVIFAYVADFTQEHERSTAYGWVSATFAASLVSSPAIGTYLSANYGDSLVVLVATLVALLDICFILIAVPESLSEKIRPASWGA-------------------------------------------------------------------------QISWKQADPFASLKKVGKDSTVLLICITVFLSYLPEAGQYSSFFLYLRQVIGFGSVKIVAFIAMVGILSIVAQTVFLSKLMRSLGNKNTVLLGLGFQMLQLAWYGFGSQAWMMWAAGTVAAMSSITFPAVSALISRNAESDQQGVAQGIVTGIRGLCNGLGPALYGFIFYMFHVELSELGPKLNS---DDDPLQGAFIPGPPFLFGACIVLMSFLVALFIP-------EYRKTSGVQKHNNSTSGSLSTPPERGSDEDIEPLLQDSSIWELS-FEEPGNQCTEL----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5SR56-1", "uniprot_id": "S71A2_HUMAN", "id": "Q5SR56-1", "name": "Solute carrier family 71 member 2", "aln": "MSVE--PPPELEEKAASEPEAGAMPEKRAGAQAAGSTWLQGFGRPSVYHAAIVIFLEFFAWGLLTTPMLTVLHETFSQHTFLMNGLIQGVKGLLSFLSAPLIGALSDVWGRKPFLLGTVFFTCFPIPLMRISPWWYFAMISVSGVFSVTFSVIFAYVADVTQEHERSTAYGWVSATFAASLVSSPAIGAYLSASYGDSLVVLVATVVALLDICFILVAVPESLPEKMRPVSWGA-------------------------------------------------------------------------QISWKQADPFASLKKVGKDSTVLLICITVFLSYLPEAGQYSSFFLYLRQVIGFGSVKIAAFIAMVGILSIVAQTAFLSILMRSLGNKNTVLLGLGFQMLQLAWYGFGSQAWMMWAAGTVAAMSSITFPAISALVSRNAESDQQGVAQGIITGIRGLCNGLGPALYGFIFYMFHVELTELGPKLNS---NNVPLQGAVIPGPPFLFGACIVLMSFLVALFIP-------EYSKASGVQKHSNSSSGSLTNTPERGSDEDIEPLLQDSSIWELSSFEEPGNQCTEL----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RM35-1", "uniprot_id": "A0A8M1RM35_DANRE", "id": "A0A8M1RM35-1", "name": "", "aln": "-----------------------MLIKYMRQRSVG--------RAKVAHAVVVIFMEFFAWGLLTTPMLTVLHDTFPQHTFLMNGLIQGVKGLLSFMSAPLVGALSDVWGRKSFLLLTVFFTCAPIPLMRISPWWFFALMSVSGLFSVTFSVIFAYVADITEEHERSTAYGLVSATFAASLVTSPAIGAFLSIHYGDSLVVLLATIIAVLDILFVLLVVPESLPDKMRLSSWGF-------------------------------------------------------------------------PISWEQADPFASLRKVGKDSTVLLICVTVLLSYLPEAGQYSSFFLYLGQVINFSSAAIAGFIAMVGILSIGAQTLLLSVLMKKIGNKSTVLLGLGFQLFQLAWYGFGSEPWMMWAAGAVAALSSITFPAISALVSRCTDRDQQGAVQGIITGIRGLCNGLGPFLFGFIFFLFNVELNDISTVQSNSAVTPDTKQKSVVPGPPFVFGACTVVLALLVAVFIPSQPAPLVKTCSSSSTCVVTEPMSSILAGGSLPASDEDIEPLLQDSSL--------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VPD8-1", "uniprot_id": "Q9VPD8_DROME", "id": "Q9VPD8-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "-----------------------MSKFGLKKLLVSLASTSGIGKPSVGHILVVVFLEYFAWGLLTMPMIATLKETFPDHTFLMNGLVMGVKGILSFLSSPLIGALSDIYGRKVLLLITVIFTSLPIPMMTMDNWWFFVISSISGVLGVSFSVAFAYVADVTTKEERSRSYELVSATFAASLVIAPAMGNLIMDRYGINTVVLVATLVSTTNVMFVLLAVPETLQQNVRST-----------------------------------------------------------------------------GLSWKQADPFLSLRRVGSDPNVLLLCVVMFTFLLPEAGEYSSVPAYLKLTMGFDFTELSTLVAFMAILGISIN-VTLGSIVKTLGAKNAIILGLLLELLQLILFAIGYEKWQMWLAGNVAALSSITFPAVSAYVSLYTDVETQGAVQGMITGMSGLCSGLGPALFGIVFYLSDMDLDKNRILIGS-------VSGDRTVTNPFMIGAISVFIGILLASYIP------------------DEKVSR--GRREEFSALKYIIEMEEATTI--------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VPE0-1", "uniprot_id": "Q9VPE0_DROME", "id": "Q9VPE0-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "----------------------MAQLKFLRPLVKVLVNRSGIGKASVWHAVIVTFMHYFSWGLLTVPFIEKLSGSFGNRVLLVDGLVYGVRGILGFVTTPVMGAISDFHGRKVVMLLAVATTYAPIPFMMLKSWWFFAILTVSSICGSTYSSSLAYVADTTTVENRSKGYGIVAASFGAGIAFSPSLGNYLMKSYGSASVILIAAITGLINIMFIIFAVPESLVLKEKNNMLDEESDN-----KMEDINPKERKEILNREEKLNNHVSANKSNHGTSQNLVTNKELGQQFNKEENLQNDLTEKEKIDNGSLNSSDLWEVLRKSRKDKNLLVIYLITFLSIWPFAGVDSTAPVYLKTNMGFEYEEVSMMLGLLSVLAITSN-LLLGYIINIVGAKWSIRLGLLLLLLQLFFFGFGTHHWMYWLSSILAALATIIPAANNAVASIYASPDNRGAVLGIISGIECLSEGVGPAFFGVLFFIFQDDSKN--KVNSP-------------ISMPFVISAIGVFVAIVLTGFIK----------------KETVEKAPLIYKIIDDASEDEVEPLAKTTFKYEKNNGYVKLEIDDNYDSDCKEHSFK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VPD9-1", "uniprot_id": "Q9VPD9_DROME", "id": "Q9VPD9-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "----------------------MAQLKFLRPLVKVLVNRSGIGKASVWHAVIVTFMHYFSWGLLTVPFIEKLSGSFGNRVLLVDGLVYGVRGILGFVTTPVMGAISDFHGRKVVMLLAVATTYAPIPFMMLKSWWFFAILTVSSICGSTYSSSLAYVADTTTVENRSKGYGFVAASFGAGIAFSPSLGNYLMKSYGSASVILIATITGMINILFIIFAVPESLVLKEKKVILNENNDNKVEDTKVDDISPKEKKENLNGEGKVN--VEVNKP---TSQNIVTNKELDQQFSKEENLQNDLTEKEKIDNGSLNSSDLWEVLRKSRKDKNLLVIYLITFLSIWPFAGVDSTAPVYLKTNMGFEYEEVSMMLGLLSVLAITSN-ILLGYIMNIVGAKWSIRLGLLLLFLQMLFFGFGTHHWMYWLSSILAALATIIPAANNAVASIYASPDNRGAVLGIISGIECLSEGVGPAFFGLLFFIFQDDSETDLKVNSP-------------ISMPFVISAISVFVAIVLSSFIK----------------KDTLGNE-------ETRVANENIP---------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :..* * .* *:.:*:***** *:: * :* ::.:*::**: **:*:*.*:::*::**:**. *** .:* :* * ***:* :. **:* : ::*.: . ::* :***** * .:** .* *:*:*.*.:. :*::* : ** *:*:*:: . :: *::..***:* : : * :.:* : *:: .* .:*:: : : * ** *: ** :.* : ::.::.:*.* : *. ::. :* * :: *** : ::*: :.:* . * * :. :**:::* .* .* * :. : :*.. *:::*: *..*:** ::*.:*:: . : . **::.* *.:.:::: :* . ", "identical_positions": 110, "similar_positions": 154, "identity": "18.3%" }, { "cls_id": "homologset.agr.RGD:1308378", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5FVR4-1", "uniprot_id": "ERI1_RAT", "id": "Q5FVR4-1", "name": "3'-5' exoribonuclease 1", "aln": "MEDERGREHGGDA---AQQKTPRPECEESRP-LSVEKKQRCRLDGKDTDGSKFITSNGGDFSDPVYKEIAMTNGCINRMSKEELRAKLSEFKLETRGVKDVLKKRLKNYYKKQKLMLKESNAVDSYYDYICIIDFEATCEEGNPAEFLHEIIEFPVVLLNTHSLEIEDTFQQYVRPEVNSQLSEFCIGLTGITQDQVDRADAFPQVLKKVIEWMKSKELGTKYKYCILTDGSWDMSKFLNIQCQLSRLKYPSFAKKWINIRKSYGNFYKVPRSQTKLTIMLEKLGMDYDGRPHSGLDDSKNIARIAVRMLQDGCELRINEKLHGGQLMSVSSSLPVEGAPAPQMPHSRK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TMF2-1", "uniprot_id": "ERI1_MOUSE", "id": "Q7TMF2-1", "name": "3'-5' exoribonuclease 1", "aln": "MEDERGRERGGDA---AQQKTPRPECEESRP-LSVEKKQRCRLDGKETDGSKFISSNGSDFSDPVYKEIAMTNGCINRMSKEELRAKLSEFKLETRGVKDVLKKRLKNYYKKQKLMLKESSAGDSYYDYICIIDFEATCEEGNPAEFLHEIIEFPVVLLNTHTLEIEDTFQQYVRPEVNAQLSEFCIGLTGITQDQVDRADAFPQVLKKVIEWMKSKELGTKYKYCILTDGSWDMSKFLSIQCRLSRLKHPAFAKKWINIRKSYGNFYKVPRSQTKLTIMLEKLGMDYDGRPHSGLDDSKNIARIAVRMLQDGCELRINEKILGGQLMSVSSSLPVEGAPAPQMPHSRK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IV48-1", "uniprot_id": "ERI1_HUMAN", "id": "Q8IV48-1", "name": "3'-5' exoribonuclease 1", "aln": "MEDPQSKEPAGEAVALALLESPRPEGGEEPPRPSPEETQQCKFDGQETKGSKFITSSASDFSDPVYKEIAITNGCINRMSKEELRAKLSEFKLETRGVKDVLKKRLKNYYKKQKLMLKESNFADSYYDYICIIDFEATCEEGNPPEFVHEIIEFPVVLLNTHTLEIEDTFQQYVRPEINTQLSDFCISLTGITQDQVDRADTFPQVLKKVIDWMKLKELGTKYKYSLLTDGSWDMSKFLNIQCQLSRLKYPPFAKKWINIRKSYGNFYKVPRSQTKLTIMLEKLGMDYDGRPHCGLDDSKNIARIAVRMLQDGCELRINEKMHAGQLMSVSSSLPIEGTPPPQMPHFRK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** :.:* .*:* * ::**** *. * * *:.*:*::**::*.*****:*...***********:*************************************************. *********************.**:**************:**************:*:***:***.*************:*********:*** *********.:************.***:*****:*.*****************************************.***************************: .***********:**:*.***** **", "identical_positions": 288, "similar_positions": 43, "identity": "82.52%" }, { "cls_id": "homologset.agr.RGD:1308379", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P55091-1", "uniprot_id": "CTRC_RAT", "id": "P55091-1", "name": "Chymotrypsin-C", "aln": "MLGITVLAAILACASCCGNPAFPPNLSTRVVGGEDAVPNSWPWQVSLQYLKDDTWRHTCGGSLITTSHVLTAAHCINKDFTYRVGLGKYNLTVEDEEGSVYAEVDTIYVHEKWNRLFLWNDIAIIKLAEP-------VELSNTIQVACIPEEGSLLPQDYPCYVTGWGRLWTNGPIAEVLQQGLQPIVSHATCSRLDWWFIKVRKTMVCAGGDGVIS-ACNGDSGGPLNCQAEDGSWQVHGIVSFGSSSGCNVHKKPVVFTRVSAYNDWINEKIQL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3SYP2-1", "uniprot_id": "CTRC_MOUSE", "id": "Q3SYP2-1", "name": "Chymotrypsin-C", "aln": "MLGITVLAAILACASSCGDPTFPPNLSARVVGGEDAVPNSWPWQVSLQYLRDDTWRHTCGGSLITTSHVLTAAHCINTNLTYRVGLGKYNLTVEDEEGSVYAEVDTIYVHEKWNRLLLWNDIAIIKLAEP-------VELSDTIQVACIPEQDSLLPGDYPCYVTGWGRLWTNGPIAEVLQQGLQPIVNHTTCSRLDWWFIKVRETMVCAGGDGVIS-ACNGDSGGPLNCPVEDGLWQVHGIVSFGSSRGCNTYKKPVVFTRVSAYIDWIKEKIQL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99895-1", "uniprot_id": "CTRC_HUMAN", "id": "Q99895-1", "name": "Chymotrypsin-C", "aln": "MLGITVLAALLACASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEH-------VELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDGVIS-ACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VPN7-1", "uniprot_id": "Q9VPN7_DROME", "id": "Q9VPN7-1", "name": "Peptidase S1 domain-containing protein", "aln": "MKQFAVIFALALASVSAISVPQPGFPEGRIINGYEAAKGEAPYIVSLQTTSN---SHFCAGSLLDEVTIVTAAHCLTYNQGQAVAGAHSRTDQENVQIRKFTNAQYV-IHENYGGGVGPNDIGLILLKEEDAFDLNAVARDGSNPVSAVSLPSKTFQGTSDGYLYGWGRDNS-GLLPLNLQKLDAIIVDYNECKAALPSNNSLAETNVCTHTPGKADGSCNGDSGGPLVSQSSSRGAELIGIVSWGYTP-CLSTTYPSVYTSVSSFLPWIDENRKAK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* ::*: *: .: .. . * . *::.* :* . *: :*** : * *.*:*: ::*****:. *. .: . *: : :. .: : :*:.:. . ***.:* * * * ..: *:.:. .. : *: **** : * :. **: :*.: *. : :* **: * . :********* . .. :: ****:* * . * *:* **:: **.*: : ", "identical_positions": 68, "similar_positions": 81, "identity": "24.55%" }, { "cls_id": "homologset.agr.RGD:1308380", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZS79-1", "uniprot_id": "D3ZS79_RAT", "id": "D3ZS79-1", "name": "tRNA (uracil-O(2)-)-methyltransferase", "aln": "MLFRVASSQCAESADMEELRRVPLDDPDSLLPGGFWAAVTVWLERPQVANKRLCGARIEARGRTLRPSAQA------------ECGPRQGQG-----------HGLE---------------------REPGQGS---------RADREGTAPAADLDLLWNRVSQSLVHSNPEILTFYG-PSLGSPPEAAQELDLVLRTVIPKASPHFPFTEPKKELVVQDVSSGSVTFLPLEEDNEENLEVKMSNVYQLRLHHSEGEWFISVLIFCPERWHSDGVVYPKPTWLAEELLSKLARWAVENRKSEFKSTLSLVSVLRYGRMYQELKEKYR----DMVKVWPEVTDPEKFVYEDVAIATYLLILWEEERAEKGITTKQSFVDLGCGNGLLVHILSNEGHPGRGIDVRRRKIWDMYGPQTQ---LEEGSITPSDKTLFPGVDWLIGNHSDELTPWIPVIAARSSYTCRFFVLPCCFFDFVG-RYRRRQSKKTQYREYLDFVLEVGLSCGFHVQEDCLRIPSTKRVCLIGKSRTYLPSAEVWMDEQRTRYLHSRQGLPQSLPGGGHAPSVPQIAAHDDDAGHQDSHRTFDAGAECMPEGLAAERGTGAPATGLWVPGFCPREKAERVRNCAALPRDFIDQVVLQVANLLLDGKRFNTGNSEAGSLKTWNGGGSLSLAEVAAELNSETLQQLKRECGGLQTLLRNSHQVFEVLNGRVHIRDWRRE-LQREKPPEGKRSLSAEVFKTRICWFFTHHPDGCVLPAACCPFAHGLEELRPSQTLKKQRQAP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D2Q2-1", "uniprot_id": "TRM44_MOUSE", "id": "Q9D2Q2-1", "name": "Probable tRNA (uracil-O(2)-)-methyltransferase", "aln": "---------------MEELGRVRLSDPDALLPAGFWAAVTVWLERPQVANKRLCGARMEARGRTLRSHAQA------------ECGPRQGQG-----------HGLE---------------------REPGQASPKGEPESGPRASREGTAPAADLNSLWDRVSQSLVHANPEMLAFLCGPSLGPQPEAAQELDLILRTVIPKASPHSPLTEPKKELVVQDVSSGSVTFLPLEEDNEGNLEVKTSNVYQLHLHHNEGEWFISVLIFCPERWHSDGVVYPKPAWLGEELLSKLARWAVENRKSEFKSTLSLVSILRYSRMYQELKEKYR----DMVKVWPEVTDPEKFVYEDVAIATYLLILWEEERAEKGVTTKQSFVDLGCGNGLLVHILSNEGHPGRGIDIRRRKIWDMYGPQTQ---LEEGSITPSDETLFPGVDWLIGNHSDELTPWIPVIAARSSYTCRFFVLPCCFFDFVG-RYQRQQSRKTQYREYLDFVLEVGLSCGFHVQEDCLRIPSTKRVCLIGKSRTYPPSAEVWMDEQRTRYLHSRQGHPQSRPGGAHAPSAPQTAAHD--AGLQDSCRTVNAGSECVLEGLAAERGAGAPAPGLWVPGFCPREKAERVRNCAALPRDFVDQVVLQVANLLLDRKKFNTGNSEARSLKPWNGGGSLSLAEVAAELNSETLQRLKRECGGLQTLLKNSHQVFEVLNGRVHIRDWRQE-LQRGKPPEAKQNLSAAVFKTRICWFFAHHPDGCVLPAAQCPFAHGPEELRLSQTLKKQRQAP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IYL2-1", "uniprot_id": "TRM44_HUMAN", "id": "Q8IYL2-1", "name": "Probable tRNA (uracil-O(2)-)-methyltransferase", "aln": "---------------MAEVGRTGISYPGALLPQGFWAAVEVWLERPQVANKRLCGARLEARWSAALPCAEARGPGTSAGSEQKERGPGPGQGSPGGGPGPRSLSGPEQGTACCELEEAQGQCQQEEAQREAASVPLRDSGHPGHAEGREGDFPAADLDSLWEDFSQSLARGNSELLAFLTSSGAGSQPEAQRELDVVLRTVIPKTSPHCPLTTPRREIVVQDVLNGTITFLPLEEDDEGNLKVKMSNVYQIQLSHSKEEWFISVLIFCPERWHSDGIVYPKPTWLGEELLAKLAKWSVENKKSDFKSTLSLISIMKYSKAYQELKEKYK----EMVKVWPEVTDPEKFVYEDVAIAAYLLILWEEERAERRLTARQSFVDLGCGNGLLVHILSSEGHPGRGIDVRRRKIWDMYGPQTQ---LEEDAITPNDKTLFPDVDWLIGNHSDELTPWIPVIAARSSYNCRFFVLPCCFFDFIG-RYSRRQSKKTQYREYLDFIKEVGFTCGFHVDEDCLRIPSTKRVCLVGKSRTYPSSREASVDEKRTQYIKSRRGCPVSPPGWELSPSPRWVAAGS--AGHCDGQQALDARVGCVTRAWAAEHGAGPQAEGPWLPGFHPREKAERVRNCAALPRDFIDQVVLQVANLLLGGKQLNTRSSRNGSLKTWNGGESLSLAEVANELDTETLRRLKRECGGLQTLLRNSHQVFQVVNGRVHIRDWREETLWKTKQPEAKQRLLSEACKTRLCWFFMHHPDGCALSTDCCPFAHGPAELRPPRTTPRKKIS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VHB9-1", "uniprot_id": "TRM44_DROME", "id": "Q9VHB9-1", "name": "Probable tRNA (uracil-O(2)-)-methyltransferase", "aln": "--------------------------MAAVEEAQFWQAIGILIKNYHALNKKIFEVVITQVTKQQN--------------------------------------------------------------------------------GRVCESSAEELAMSLKEDPSQRTCTG----------------------------------FTIGFKLLSKKLAENILGTGIVDFENC--------------LYECQFASDSIEGFSVGLLGGEFKLKSK----SNTNWLEFVLRPKLLSWSQSKQDEAKVKSLGLVNVEKYNDLYKELKQRHSQRLLEHWKTAQESTDPLKFIYEDLAIAAYLIVLWSQTQSEP-----TAFADLGCGNGLLVHVLNAEGYKGYGYDIRKRKLWSLYPPDTQRSLIEKAVEPNSFRLDFPGVDWLIGNHSDELSPWLPVLAGR--LNINYFLLPCCPFELSGAKFRRRNTKISAYQDFFQYVTQVSHECGYEILQDRLKIPSTKRLALLGIKRKASKAIEDLEYFVQEELRKYKTGDAK----------------------------------------------------------IKLREKEESVRNCTQVDKTIIDGLVFKIFKLILDSNED-----------KWSG--RLPMREIAQALTKEELSGIKSECGGIKTLLRNKHEVFEFCGGDLIG--------IRTPKPTATLPKSHLTIKKRSCFFKLHHPLGCPLDDAECSFIH------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q02648-1", "uniprot_id": "TRM44_YEAST", "id": "Q02648-1", "name": "tRNA (uracil-O(2)-)-methyltransferase", "aln": "-MTGDGSAHISKNNQNQHKDRFKFIVNDKSILGPQWLSLYQTDGKVTFAKSHFEQAMMNVIREPNINSTVILR----------------------------------------------------ADILKEINHAAEAGSEPKFDESVLKKFEIDNGNESGEEDVKKINIEDLNIRSCETSESLKLSPVHEFVRRIIPRNFYKDAIINQTCLILNSKDPNFQETSLIVYTPHINSEKDCPFYIPRTQSVGILLHQSVLSVHYIPFPEDKTAFTDESERVVRTAYRLLQTANKHSKGVMQG-YEKRVNHDQVVNKVNFQNTYIVLKKKYS---KFLVENWAESTDPKKHVFEDIAIAAFLIELWIK-VYGPDFRSKMQFRDLGCGNGALCYILLSESIKGLGIDARKRKSWSIYPPEVQSSLKEQVIIPSILLRPHPALKRQVP-HLEHNGRFFPVKVTHEVIAPATVVYSSEDLLKSP----QVNTAEFPPDTFIIGNHSDELTCWIPLLGHPYMVIPCCSHNFSGQRVRFNVRKRSPRSNEIKNQNNSKSTYSG----------------------------------------------------------LVDHVEYISSRVGWKVEKEMLRIPSTRNAAIIG------------------------VENATLKHFPTQAVYDMIWEDGGAEGWIQNTMSLLKRNPRNH-----------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :: . :.:: . : . : . .. . : . : : . . . : .. .. : * . . . ::. .: * **::: : * *** *.::**:***::*: ** : * ******* * ::* *. * * * *:** *.:* *:.* *: . .* :. : * :. ::** . : .: .. : : :: :: . * : . : . : * . . : : . : : : * : : :: : :: : .: : : * ** : ::*. .::: ", "identical_positions": 51, "similar_positions": 112, "identity": "6.51%" }, { "cls_id": "homologset.agr.RGD:1308381", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZG83-1", "uniprot_id": "M3K10_RAT", "id": "D3ZG83-1", "name": "Mitogen-activated protein kinase kinase kinase 10", "aln": "---MEEEEGAAAREWG------------------------ATPAGPVWTAVFDYEAVGDEELTLRRGDRVQVLSQDCAVSGDEGWWTGQLPSGRVGVFPSNYVAPAAPAAP-----TDLQLPQEIPFHELQLEEIIGVGGFGKVYRALWRGEEVAVKAARLDPERDPAVTAEQVRQEARLFGALQHPNIIALRGACLSPPNLCLVMEYARGGALSRVLAGRRVPPHVLVNWAVQVARGMNYLHNDAPVPIIHRDLKSINILILEAIENHNLADTVLKITDFGLAREWHKTTKMSAAGTYAWMAPEVIRLSLFSKSSDVWSFGVLLWELLTGEVPYREIDALAVAYGVAMNKLTLPIPSTCPEPFARLLEECWDPDPHGRPDFGSILKQLEVIEQSALFQMPLESFHSLQEDWKLEIQHMFDDLRTKEKELRSREEELLRAAQEQRFQEEQLRRREQELAEREMDIVERELHLLMSQLSQEKPRVRKR-------------------------------------------KGNFKRSRLLKLREGSSHISLPSG---------FEHKITVQASPTLDKRK---------------------GSDGAS-PPASPSIIP---------------RLRAIRLTPVDCGSS------GGSGTWSRSGPPKKEELVGGK--------------------KKGRTWGPSSTLQKERAGGEERLKALGEGSKQ-WSSSAPNLGKSPKHTPMAPGFASLN------------------EMEEFAEADEG-NNVPPSPYSTPSYLKVPLPAEASPCAQPPWEP-PAATPSRPGHGARRRCDLALLGCATLLSAVGLGADVAEARAGDGEEQRGWLDGLFFPRPGRFPRGLSPTGRP-------GGRREETAPGFGLAPSATLVSLSSVSDCNSTRSLLRSDSDEAAPTAPSPPPSLLP-------PSPSTNPLVDVELESFKKDPRQSLTPTHVTAAHAVSRGHRRTPSDGALRQREPPELTNHGP--RDPLDFPRLPDPQALFPTRRRPLEFPGRPTTLTFAP--------------------RPRPAASRPRLDPWKLVSFGRTLSISPPSRPDTPESPGPLSVQPTLLDMDMEGQS-------QDNTVPLCGAYGSH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q66L42-1", "uniprot_id": "M3K10_MOUSE", "id": "Q66L42-1", "name": "Mitogen-activated protein kinase kinase kinase 10", "aln": "---MEEEEGAAAREWG------------------------ATPAGPVWTAVFDYEAVGDEELTLRRGDRVQVLSQDCAVSGDEGWWTGQLPSGRVGVFPSNYVAPAAPAAP-----SDLQLPQEIPFHELQLEEIIGVGGFGKVYRAVWRGEEVAVKAARLDPERDPAVTAEQVRQEARLFGALQHPNIIALRGACLSPPNLCLVMEYARGGALSRVLAGRRVPPHVLVNWAVQVARGMNYLHNDAPVPIIHRDLKSINILILEAIENHNLADTVLKITDFGLAREWHKTTKMSAAGTYAWMAPEVIRLSLFSKSSDVWSFGVLLWELLTGEVPYREIDALAVAYGVAMNKLTLPIPSTCPEPFARLLEECWDPDPHGRPDFGSILKQLEVIEQSALFQMPLESFHSLQEDWKLEIQHMFDDLRTKEKELRSREEELLRAAQEQRFQEEQLRRREQELAEREMDIVERELHLLMSQLSQEKPRVRKR-------------------------------------------KGNFKRSRLLKLREGSSHISLPSG---------FEHKITVQASPTLDKRK---------------------GSDGAS-PPASPSIIP---------------RLRAIRLTPMDCGGS------SGSGTWSRSGPPKKEELVGGK--------------------KKGRTWGPSSTLQKERAGGEERLKALGEGSKQ-WSSSAPNLGKSPKHTPMAPGFASLN------------------EMEEFAEADEG-NNVPPSPYSTPSYLKVPLPAEPSPCVQAPWEP-PAVTPSRPGHGARRRCDLALLSCATLLSAVGLGADVAEARAGDGEEQRRWLDSLFFPRPGRFPRGLSPTGRP-------GGRREDTAPGLGLAPSATLVSLSSVSDCNSTRSLLRSDSDEAAPAAPSPPPSPLA-------PSPSTNPLVDVELESFKKDPRQSLTPTHVTAAHAVSRGHRRTPSDGALRQREPLELTNHGP--RDPLDFPRLPDPQALFPTRRRPLEFPGRPTTLTFAP--------------------RPRPAASRPRLDPWKLVSFGRTLSISPPSRPDTPESPGPPSVQPTLLDMDMEGQS-------QDNTVPLCGVYGSH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q02779-1", "uniprot_id": "M3K10_HUMAN", "id": "Q02779-1", "name": "Mitogen-activated protein kinase kinase kinase 10", "aln": "---MEEEEGAVAKEWG------------------------TTPAGPVWTAVFDYEAAGDEELTLRRGDRVQVLSQDCAVSGDEGWWTGQLPSGRVGVFPSNYVAPGAPAAP-----AGLQLPQEIPFHELQLEEIIGVGGFGKVYRALWRGEEVAVKAARLDPEKDPAVTAEQVCQEARLFGALQHPNIIALRGACLNPPHLCLVMEYARGGALSRVLAGRRVPPHVLVNWAVQVARGMNYLHNDAPVPIIHRDLKSINILILEAIENHNLADTVLKITDFGLAREWHKTTKMSAAGTYAWMAPEVIRLSLFSKSSDVWSFGVLLWELLTGEVPYREIDALAVAYGVAMNKLTLPIPSTCPEPFARLLEECWDPDPHGRPDFGSILKRLEVIEQSALFQMPLESFHSLQEDWKLEIQHMFDDLRTKEKELRSREEELLRAAQEQRFQEEQLRRREQELAEREMDIVERELHLLMCQLSQEKPRVRKR-------------------------------------------KGNFKRSRLLKLREGGSHISLPSG---------FEHKITVQASPTLDKRK---------------------GSDGAS-PPASPSIIP---------------RLRAIRLTPVDCGGSSSGSSSGGSGTWSRGGPPKKEELVGGK--------------------KKGRTWGPSSTLQKERVGGEERLKGLGEGSKQ-WSSSAPNLGKSPKHTPIAPGFASLN------------------EMEEFAEAEDGGSSVPPSPYSTPSYLSVPLPAEPSPGARAPWEPTPSAPPARWGHGARRRCDLALLGCATLLGAVGLGADVAEARAADGEEQRRWLDGLFFPRAGRFPRGLSPPARP-------HGRREDVGPGLGLAPSATLVSLSSVSDCNSTRSLLRSDSDEAAPAAPSPPPSPPAP---TPTPSPSTNPLVDLELESFKKDPRQSLTPTHVTAACAVSRGHRRTPSDGALGQRGPPEPAGHGPGPRDLLDFPRLPDPQALFPARRRPPEFPGRPTTLTFAP--------------------RPRPAASRPRLDPWKLVSFGRTLTISPPSRPDTPESPGPPSVQPTLLDMDMEGQN-------QDSTVPLCGAHGSH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q95UN8-1", "uniprot_id": "M3KSL_DROME", "id": "Q95UN8-1", "name": "Mitogen-activated protein kinase kinase kinase", "aln": "MLPISEEQQLQQQQQQQQLEQLHHPQIPEIPIPDLEQVETQVGDGSLWTALYDYDAQGEDELTLRRGEIVVVLSTDSEVSGDVGWWTGKIG-DKVGVFPKDFVTDEDPLQLNVSSAIGDIQPHEIEYNELDIKEVIGSGGFCKVHRGYYDGEEVAIKIAHQTGEDDMQRMRDNVLQEAKLFWALKHENIAALRGVCLN-TKLCLVMEYARGGSLNRILAG-KIPPDVLVNWAIQIARGMNYLHNEAPMSIIHRDLKSSNVLIYEAIEGNHLQQKTLKITDFGLAREMYNTQRMSAAGTYAWMPPEVISVSTYSKFSDVWSYGVLLWELITGETPYKGFDPLSVAYGVAVNTLTLPIPKTCPETWGALMKSCWQTDPHKRPGFKEILKQLESIACSKFTLTPQESFHYMQECWRKEIAGVLHDLREKEKELRNKEEQLLRVQNEQREKANLLKIREQNLRERERVLIERELVMLQPVPSKRKHKKGKKNKPLQISLPTGFRHTITAVRDKAEQPGSPSFSGLRIVALTDGHKGKTWGPSTMHQRERSLLPSQLSGGQPEWPAQTSTHSSFSKSAPNLDKKQQQQNQQQVASLTPPPGLGILGGSGGAGGTPATPLLYPGIPIILTRPNNNNIGNCKAITTTITTTTTTTTNNNNNNNNSISANNNNQLNNISTINSNNNNNQTNLTSQPNTIIVLQNGRNNSNSSTTSQSPAKIYHRARSQEYGLDHPLAYQPPPLYLVTDDSSETDTVASPTGCFHFLKSGNSSAASGAVHLHRFGGSLGNSPAVGRKKHSLDSSSHHPPANGSNSFALPNQLTLPSEDNNTYDHAFYRDVIKKMSMASSERVNSKSSGDLTMYNSSTPLTARDCDDAEEAFEGGRFQRNFSGSQFPRHCFFTRQEEEGEAEDEDAVAAEVDTADADADDECQVPASQMRQNSTTSRKSSVTFQSVSFEEPDFVATPRTTARSDLYTSSASISFATYRSASPSLSSSSTTASASPSIASTEAVNGYHMQENSILNTRRMQDVQPHPDVIKLRAQEQRQQTKNQKKQRPKHITKSKSVEAPVEGQHHEHDDHNDPQHQHHSAGSSKIRALFNLFTRSRKKYSKLAEHNMVGGPEFCAIDPYQTDLAMGGSSRSLKRKGKKPQTQSCEQLERC", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.**: :: . *.:***::**:* *::*******: * *** *. **** *****:: .:*****.::*: * . *:** ::**:::*:** *** **:*. : *****:* *: * * ::* ***:** **:* ** ****.**. .:***********:*.*:*** ::**.******:*:*********:**:.******** *:** ****.::* :..*********** ::* :**********.**** :* :** *****:*******:***.**: :*.*:******:*.******.****.:. *::.**:.*** **.* .***:** * * : * **** :** *: ** ::.*** ******.:**:***. :*** : : *: ***:* *** ::**** :* *:.* : *: **: . :: ** . * ** *. :::*.***:: **.**. .**:* : * . :** * : ....: * .. : ::: : ::**. . *** .:. . .* :. * .: : ..* * ...:. : .** . .:..*. : . * . :* * * . ... . . . *: .*. * : .:: ..*:: .:. * *. . *** *.:* . * .. :. .:*... .. .: .:*: . * :*.:* : :: : . * .::.. : . *:. . :* :*: ::: :.* . :.::.. : : : :* .* : . :* :: : **. :* : : : :*. .:: . : . * :. : .* :::* *: * *.. :. . * ", "identical_positions": 330, "similar_positions": 289, "identity": "28.67%" }, { "cls_id": "homologset.agr.RGD:1308383", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4ADD7-1", "uniprot_id": "D4ADD7_RAT", "id": "D4ADD7-1", "name": "Glutaredoxin-related protein 5, mitochondrial", "aln": "MRLPGKAHRYGVSDMIGGIEPVLSNHETHPRAYPMRTSSGPAGHQGLCKPSGGRRSGDQRAGMSASLSRAAAALLRWGRGAGGGVLPRAGVRAASS----GGQAEQLDALVKKDKVVVFLKGTPEQPQCGFSNAVVQILRLHGVR--DYAAYNVLEDPELRQGIKDYSNWPTIPQVYLNGEFVGGCDILLQMHQNGDLVEELKKLGIRSALIDEK-DQDSK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80Y14-1", "uniprot_id": "GLRX5_MOUSE", "id": "Q80Y14-1", "name": "Glutaredoxin-related protein 5, mitochondrial", "aln": "--------------------------------------------------------------MSASLSRAAAALLRWGRSAGGGGLPGAGVRAASS----GGQAEQLDALVKKDKVVVFLKGTPEQPQCGFSNAVVQILRLHGVR--DYAAYNVLDDPELRQGIKDYSNWPTIPQVYLNGEFVGGCDILLQMHQNGDLVEELKKLGIRSALVDEK-DQDSK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86SX6-1", "uniprot_id": "GLRX5_HUMAN", "id": "Q86SX6-1", "name": "Glutaredoxin-related protein 5, mitochondrial", "aln": "--------------------------------------------------------------MSGSLGRAAAALLRWGRGAGGGGLWGPGVRAAGSGAGGGGSAEQLDALVKKDKVVVFLKGTPEQPQCGFSNAVVQILRLHGVR--DYAAYNVLDDPELRQGIKDYSNWPTIPQVYLNGEFVGGCDILLQMHQNGDLVEELKKLGIHSALLDEKKDQDSK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PBM1-1", "uniprot_id": "GLRX5_DANRE", "id": "Q6PBM1-1", "name": "Glutaredoxin-related protein 5, mitochondrial", "aln": "----------------------------------------------------------MNSVFRSTARCLRSATWQYKTAHKNGELSVGRARLMCS----SAGQKNLEEMVKKDKVVVFMKGTPAQPMCGFSNAVVQILRMHGVD--NYASYNVLDDQDVRQGIKTFSNWPTIPQVFFNGEFVGGCDILLQMHQSGDLVEELQKLGIRSALLDQE--KESK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q02784-1", "uniprot_id": "GLRX5_YEAST", "id": "Q02784-1", "name": "Monothiol glutaredoxin-5, mitochondrial", "aln": "-----------------------------------------------------------------MFLPKFNPIRSFSPILRAKTLLRYQNRMYLS----TEIRKAIEDAIESAPVVLFMKGTPEFPKCGFSRATIGLLGNQGVDPAKFAAYNVLEDPELREGIKEFSEWPTIPQLYVNKEFIGGCDVITSMARSGELADLLEEAQALVPEEEEE-TKDR-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : * * * : :: ::. **:*:**** * ****.*.: :* :** .:*:****:* ::*:*** :*:******::.* **:****:: .* :.*:*.: *:: . ::: :: ", "identical_positions": 47, "similar_positions": 44, "identity": "21.27%" }, { "cls_id": "homologset.agr.RGD:1308384", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5MPA9-1", "uniprot_id": "DCLK2_RAT", "id": "Q5MPA9-1", "name": "Serine/threonine-protein kinase DCLK2", "aln": "----------------------------------------------------------------------MASTRSIELEHFEERDKRPRP---------GSRRGAPSSSGGSSISGPKGNGLIPSPAHSAHCS-------FYRTRTLQALSSEKKAKKARFYRNGDRYFKGLVFAISSDRFRSFDALLIELTRSLSDNVNLPQGVRTIYTVDGSRKVTSLDELLEGESYVCASN-EPFRKVDYTKNVNPNWSVNIKGGTTRTLAVAS-------------------------------AKSEVKESKDFIKPKLVTVIRSGVKPRKAVRILLNKKTAHSFEQVLTDITEAIKLDSGVVKRLCTLDGKQVTCLQDFFGDDDVFIACGPEKYRYAQDDFVLDHSECRVLKSSYSRASAAKYSGSRSPGLSRRSKSPASVKRAGHSSAYSTAKSPVNGTPSSQLSTPKSTKSSSSSPTSPGSFRGLKQISAQGRSSSNVNGGPELDRCMSPEGVNGNRCSESFTLLEKYRIGKVIGDGNFAVVKECMDRSTGKEFALKIIDKAKCCGKEHLIENEVSILRRVKHPNIIMLVEEMETTTELFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLASALRYLHGLSIVHRDIKPENLLVCEYPDG-TKSLKLGDFGLATVVEGPLYTVCGTPTYVAPEIIAETGYGLKVDVWAAGVITYILLCGFPPFRSENNLQEDLFDQILAGKLEFPAPYWDNITDSAKELISQMLQVNVEARCTAGEILSHPWVSDDASQENNMQAEVTGKLKQHFNNALPKQNSTTTGVSVIMNTALDKEGQVFCSKHCRDSSKSSREQTS--------------AREAPPPPESPRPPGPPATSGCDPAGTWRRHRD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PGN3-1", "uniprot_id": "DCLK2_MOUSE", "id": "Q6PGN3-1", "name": "Serine/threonine-protein kinase DCLK2", "aln": "----------------------------------------------------------------------MASTRSIELEHFEERDKRPRP---------GSRRGAPSSSGGSSISGPKGNGLIPSPAHSAHCS-------FYRTRTLQALSSEKKAKKARFYRNGDRYFKGLVFAISNDRFRSFDALLIELTRSLSDNVNLPQGVRTIYTIDGSRKVTSLDELLEGESYVCASN-EPFRKVDYTKNVNPNWSVNIKGGTTRTLAVAS-------------------------------AKSEVKESKDFIKPKLVTVIRSGVKPRKAVRILLNKKTAHSFEQVLTDITEAIKLDSGVVKRLCTLDGKQVTCLQDFFGDDDVFIACGPEKYRYAQDDFVLDHSECRVLKSSYSRASAAKYSGSRSPGFSRRSKSPASVN----------------GTPSSQLSTPKSTKSSSSSPTSPGSFRGLKQISAQGRSSSNVNGGPELDRCLSPEGVNGNRCSESFPLLEKYRIGKVIGDGNFAVVKECVDRYTGKEFALKIIDKAKCCGKEHLIENEVSILRRVKHPNIIMLVEEMETATDLFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLHSLSIVHRDIKPENLLVCEYPDG-TKSLKLGDFGLATVVEGPLYTVCGTPTYVAPEIIAETGYGLKVDVWAAGVITYILLCGFPPFRSENNLQEDLFDQILAGKLEFPAPYWDNITDSAKELISQMLQVNVEARCTAGEILSHPWVSDDASQENNMQAEVTGKLKQHFNNALPKQNSTTTGVSVIMNTALDKEGQIFCSKLCQDSSRPSREQTSPVPP---------SAQEAPPPLESPRPPGPPATSGCDLAGTWRRHRD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N568-1", "uniprot_id": "DCLK2_HUMAN", "id": "Q8N568-1", "name": "Serine/threonine-protein kinase DCLK2", "aln": "----------------------------------------------------------------------MASTRSIELEHFEERDKRPRP---------GSRRGAPSSSGGSSSSGPKGNGLIPSPAHSAHCS-------FYRTRTLQALSSEKKAKKARFYRNGDRYFKGLVFAISSDRFRSFDALLIELTRSLSDNVNLPQGVRTIYTIDGSRKVTSLDELLEGESYVCASN-EPFRKVDYTKNINPNWSVNIKGGTSRALAAASS------------------------------VKSEVKESKDFIKPKLVTVIRSGVKPRKAVRILLNKKTAHSFEQVLTDITEAIKLDSGVVKRLCTLDGKQVTCLQDFFGDDDVFIACGPEKFRYAQDDFVLDHSECRVLKSSYSRSSAVKYSGSKSPGPSRRSKSPASVN----------------GTPSSQLSTPKSTKSSSSSPTSPGSFRGLKQISAHGRSSSNVNGGPELDRCISPEGVNGNRCSESSTLLEKYKIGKVIGDGNFAVVKECIDRSTGKEFALKIIDKAKCCGKEHLIENEVSILRRVKHPNIIMLVEEMETATELFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLHGLSIVHRDIKPENLLVCEYPDG-TKSLKLGDFGLATVVEGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPFRSENNLQEDLFDQILAGKLEFPAPYWDNITDSAKELISQMLQVNVEARCTAGQILSHPWVSDDASQENNMQAEVTGKLKQHFNNALPKQNSTTTGVSVIMNTALDKEGQIFCSKHCQDSGRPGMEPISPVPPSVEEIPVPGEAVPAPTPPESPTPHPPPAAPGGERAGTWRRHRD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7PLI7-1", "uniprot_id": "DCLK_DROME", "id": "Q7PLI7-1", "name": "Serine/threonine-protein kinase CG17528", "aln": "MELEKVKINSLHCNDAVLSSLQASPSATSPQSVPSKANVVTEASIIEKTNQPHNVQEDNNYNRDCDSPESSSSEQDKELDDLRNLHSSSLTNSVVVGKSTGSLNGVYSITSVTSETKTLESVVTTNSASGSACLSNTPTADHIKKRIPSSRTPTRKALRIKFYRNGDRFYPGITIPVSNERYRSFERLFEDLTRLLEENVKIPGAVRTIYNLCG-KKITSLDELEDGQSYVCSCNNENFKKVEYNTGSQPLSNLPLSNSRSNSHRLAKCRPSSPLKNGLLAGSSPFPACGGGTGNGSPLIASRLSDRVTVVHPRIVTLIRSGTKPRRIMRLLLNKRNSPSFDHVLTAITQVVRLDTGYVRKVFTLSGIPVVRLSDFFGSDDVFFAYGTERIN-TAEDFKLEAEEQRAIN-------VIRKTMRTTGTTCKGPKPKMPIK-------------------SKKVYPPLVDSEPFKAETTPEDDRHAALLTSTGMEINELPSN----------------------IRNTYSLGRIIGDGNFAIVFKIKHRQTGHSYALKIIDKNKCKGKEHYIDAEVRVMKKLNHPHIISLILSVDQNTNMYLVLEYVSGGDLFDAITQVTRFSENQSRIMIRHLGAAMTYLHSMGIVHRDIKPENLLVKLDEHGNVLELKLADFGLACEVNDLLYAVCGTPTYVAPEILLEVGYGLKIDVWAAGIILYILLCGFPPFVAPDNQQEPLFDAIISGIYEFPDPYWSDIGDGVRDLIANMLQADPDVRFTSEDILDHSWTIGNKGNECTTYKR------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* :. **:.:.: .. . . ** .*. * :. :* : . . : ...* .: * . :.* .: :. :** : :*******:: *:.:.:*.:*:***: *: :*** *.:**::* .*****.: * :*:****** :*:****:.* * *:**:*... :* .: :... :.: *. *.:.: .::*::**:****.***: :*:****:.: **::*** **:.::**:* *::: **.* *. *.****.****:* *.*: . : :** *: .* *.:: . : : : .: .*. .:: *.:: .* ... .: *:* . * ::: * . .:: .. : :.* :*::*******:* : .* **:.:******* ** **** *: ** ::::::**:** *: .:: *:::**:* *.*********. *:::*.:. *: :*. *: ***.:.************* .* . .***.***** *:. **:************: *.*****:*:****:* ********** : :* ** *** *::* *** ***.:* *..::**::***.: :.* *: :**.*.*. .: .:* . . ", "identical_positions": 258, "similar_positions": 233, "identity": "28.67%" }, { "cls_id": "homologset.agr.RGD:1308385", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZCM8-1", "uniprot_id": "D3ZCM8_RAT", "id": "D3ZCM8-1", "name": "", "aln": "MWKRTDPQAKIKAGDRPQTCHSLALGSATESALPHPLELSDFQSFSVFEDISHHIKEGGAQLVKKVNAIFQLDITKDGKTILQWTIDLKNGSGDMYLGSAR-LPADTIFIIPDTVFTELVVGKMNPQKAFLAGKFKVRGKVLLSQKLERIFREWAKF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DAH1-1", "uniprot_id": "SCP2D_MOUSE", "id": "Q9DAH1-1", "name": "SCP2 sterol-binding domain-containing protein 1", "aln": "MWKRPDPQAKIKAGDRPQTCQSLALGSATESALPQALKLSDFQNFSVFEDISQHIKEVGAQLVKKVNAIFQLDITKDGKTILQWTIDLKNGAGDMYLGSAR-LPADTVFIIPDSVFTELVVGKINPQKAFLAGKFKVRGKVLLSQKLERIFREWAKI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UJQ7-1", "uniprot_id": "SCP2D_HUMAN", "id": "Q9UJQ7-1", "name": "SCP2 sterol-binding domain-containing protein 1", "aln": "MWKRSDHQPKIKAEDGPLVGQFEVLGSVPEPAMPHPLELSEFESFPVFQDIRLHIREVGAQLVKKVNAVFQLDITKNGKTILRWTIDLKNGSGDMYPGPAR-LPADTVFTIPESVFMELVLGKMNPQKAFLAGKFKVSGKVLLSWKLERVFKDWAKF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VY92-1", "uniprot_id": "Q9VY92_DROME", "id": "Q9VY92-1", "name": "SCP2 domain-containing protein", "aln": "---------------------------------------MSLQSDAVFQKIIDGLKE-NEAKAKAVNGVFLYKITKDGKVAKEWTLDCKN--AKAYEGPAQGIKVDTTLTVADEDMVDIALGKLNPQAAFMKGKLKIAGNIMLTQKLAPLLKTDAKL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .::. .**:.* ::* . .* **.:* .***:**. .**:* ** .. * *.*: : .** : :.: : ::.:**:*** **: **:*: *:::*: ** ::: **:", "identical_positions": 39, "similar_positions": 45, "identity": "24.84%" }, { "cls_id": "homologset.agr.RGD:1308386", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q99LY2-1", "uniprot_id": "GDPD3_MOUSE", "id": "Q99LY2-1", "name": "Lysophospholipase D GDPD3", "aln": "-MIPLLYFVLPTLGS---YVMLSIFFLRRPHLLHTPRAPVFPIRLAAHRGGSGERLENTMEAVENSMAQRADLLEFDCQLTRDGVVVVSHDKNLSRQSGLNKDVNTLDFEELPLYKEELEIYFSPGHFAHGSDRHMISLEDVFQKFPRTPMCLEVKERNEELIHKVANLTRRFDRNEITIWAAEKSSVMKRCRAANPEMPMAFTIWRSFWILLLYYLGLLPFVSIPEKF-FFCFLPTIINRTYFPFRCGWMNQLSATITKWIIMRKSLIRHLQ-DRGVQVLFWCLNEESDFEVAFSLGANGVMTDYPTALRHYLDKQEEETQPPQPEALSCLSLKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A1N8-1", "uniprot_id": "D4A1N8_RAT", "id": "D4A1N8-1", "name": "Lysophospholipase D GDPD3", "aln": "-MIPLVYFVLPTLGS---YVILSIFFLRRPHLLHTPWAPGFSIRLAAHRGGSGERLENTMEAIENSMAQRADLLEFDCQLTRDGVVVVSHDKNLSRQSGLNKDINTLDFAQLPLYKEELEIYFSPGHFAHGSDRHMISLEDVFQKFPRTPMCLEIKEKNEELIHKVANMARRFNRNEITIWTSEKNSIMKRCKAANPEMPTAFTIWRSFWILLLYYLGLLPFVSIPEKF-FFCFLPTIINRTYFPFSCGWMNKLSATVTKWAIMRKSLIQYLQ-DRGVQVLFWCLNEESDFEVAFSLGANGVMTDYPTALRHYLDKQE------QRDSASSV----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7L5L3-2", "uniprot_id": "GDPD3_HUMAN", "id": "Q7L5L3-2", "name": "Lysophospholipase D GDPD3", "aln": "-MSLLLYYALPALGS---YAMLSIFFLRRPHLLHTPRAPTFRIRLGAHRGGSGELLENTMEAMENSMAQRSDLLELDCQLTRDRVVVVSHDENLCRQSGLNRDVGSLDFEDLPLYKEKLEVYFSPGHFAHGSDRRMVRLEDLFQRFPRTPMSVEIKGKNEELIREIAGLVRRYDRNEITIWASEKSSVMKKCKAANPEMPLSFTISRGFWVLLSYYLGLLPFIPIPEKF-FFCFLPNIINRTYFPFSCSCLNQLLAVVSKWLIMRKSLIRHLE-ERGVQVVFWCLNEESDFEAAFSVGATGVITDYPTALRHYLDNHG-------PAARTS-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6Z9C9-1", "uniprot_id": "A0A8M6Z9C9_DANRE", "id": "A0A8M6Z9C9-1", "name": "", "aln": "-MDTVSWVLLLCLAVL-FYVVCSLFLLRYPLILHKRKRLEFYCRHISHRGGSGERIENTMEAFTHAVSAGTDMLEMDCHLTLDGYVVVSHDNNLLRQTGDDKTVSSLKFQDLPLYEEKLEVTFYVGHYSTGKDRRFVLLENVLKNFPNMPMTLEIKENNDLLIKKVSNLVHKYGREHITVWASEEHEVMAKCLKQNPSMPYMFTMRRVIMLLLLFYTGLLPFVPLGESV-LMFYLPRIINRTYIPEEAYMKNRFVVYLLQKLITWKSLFEHLI-KRGLQVQLFVCNEETDMAAAFAMGATGVMTDYPTVLSDYIRKHP-------PPPAVY-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q08959-1", "uniprot_id": "PGC1_YEAST", "id": "Q08959-1", "name": "Phosphatidylglycerol phospholipase C", "aln": "MVEIVGHRAFKARYPENTLLAFEKAYAAGADVIETDLQMTSDGMVVVNHDSDTGRMWDKNLVIGESTWEEVKRLRCKEDGSLAMMTLKEILTWAVCHPGAKLMLDIKFTNEKIIMIKTFVIMLEVKNDLKFWQERITWGLWLLDWYDFGIETGVLKDFKVIVISLSLDIASQFVKRSLTLNDP-HYKLFGISVHFVSSWTSQFRLRLLPVLMKNDIKVYLWTVNKPIDFKYLCELPIHGAITDDPIKARKLCDGHTVAKKPTAEKKFVAPSLASVDGLRFHAFIKVYNILCTLLYSKWVHIKLCGWSIAYVIFLFLRT----------IHFL----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : . . ::.. ::... : :. .. .: . *. . . : .: . :.* . :. : : : : : : : :.:: ::. : :* : :* .:. :: :. :*: . . .:: . .. . * : :: * : .. : ** * * . . : * : * *::. : : :: . : .:. . :: : ", "identical_positions": 14, "similar_positions": 97, "identity": "4.17%" }, { "cls_id": "homologset.agr.RGD:1308387", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8N7UQQ7-1", "uniprot_id": "A0A8N7UQQ7_DANRE", "id": "A0A8N7UQQ7-1", "name": "", "aln": "-----------------------------MEQFSDDELDHAAEEDSDKEDQDLDKMFG-----------------------------AWLGELDKLTKSLDDGRP-EKVQKAPLRQDSNMANMAYRFSVYNINEALNQGDAVDLDALMADLCSIEQELSTIGKPSSSSSRLGLTGDTKLRQKPPAGRSHSTKHTGGSSSSGGSTSSSTRASPASTVRLSSSSSSSRPPLASNFSLDDITAQLEKASQSMDEAARQGSTPSAAYSSSTVRRPASHHHHHRRTGSVGTVTEHEVRSFVHSSRASINSASASSMDSLDIDKPLSDQ---DGVQDGQ------------GQPS---------------TEHSYLDRETSLILKSIAGKPSHLLTKEEQAAKQKAEKIRVALEKIKEAQVKKLVVRVHLSDESSKTMMVDERQTVRQVLDSLLDKSHCGYSLDWSLVEIITELQMERIFEDHENLVENLLNWTRDSTNRLMFIERIEKYALFKNPQNYLLGR--KETCEMADRNKEALLEECFGGSTISVPEIEGVLWLKDDGKKSWKKRYFLLRASGIYYVPKGKAKASRDLVCFLQLDHVNVYLGQDYRSKYKAPTDYCMVLKHP---QIQKKSQYIKYLCCDDVRMLHQWVNGIRIAKYGKQLYVNYQEAMRRTEAAHDWSSLSSSSIKSCSSS--SSLPESQSNHSSQSDSGVSETTSSGHVRSQSVVSSIFSEAWKRGNQADE-----PKMRIDGPPAQPARASYP--------LQLPPLPQSLQSRSSYSGVSPASPSS--------------PPSPPPPPPPPPPLPN---PTHHSTPVVFTKYSTLARLQNISQAPNHYKQTPLLAAQQQPTPPVPPPQCLKPLMNNTTEVASSPPPAPPPPPPPEMPVPGSAMAVLKHAP--------ISPQYTPPPPPEEDP---------------------------------------------------------------------SYLHSNG-----------------------------------------------------------------------------------YLPPPPPPEQ---LKYPPPLSTNGLQQFLAQKFPNMTYDFSP-VQQDEEPPPPPP------------------VCFSPPPQQSGPPAP-------------PKTFTGGFPPQTAPKPGHGISPISPVPPSLSPTPSLMKKQQSLSSGHSPNQPPPTLPKQYSLSSKAPSVSAPISPTQSLVKQIVNQFP-------DTLDGSK------GPISPPVVKNKPKWQPGGQAQPQ--SPEFPPPPPESTLEFPPPPAPSPPPASQPSGKSGSP-------------IKKSPSTSSNSSTGSGGKKPPPTPQRNSSMKATSSVEYQESKK--VEDLVSMFGQTSQAPPSSFSTPSSTTGSPSKESSR---ALTKPGKINLA--NLPLALQG---------RQSHCRQSSADFPSPP--LDCEFPPPPPDSELL-PPPPLPSELH-IGAPKVAVVNPQPQHSSSSTSSWKQSSLKKMPPPTMHRRSSGPPEQLALSPPPQQMPLSSFNSQIPPTSPKANLSMQPNFLEDLNRTLKRKSMTRHGSLTSSRIS-AKLEPVATMDDMALPPPPPELLLGQQKKGG--YTSANISGYATLRRGPPPAPPKRDQNTKLTSEW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3AQ39-1", "uniprot_id": "A0A8M3AQ39_DANRE", "id": "A0A8M3AQ39-1", "name": "", "aln": "-----------------------------MEQVSDDELDHAAEEDSDKEDQDLDKMFG-----------------------------AWLGELDKLTQSLDDGRP-EKVQKAPLRQETNLANFSYRFSMYNINEAINQGETVDLDALMADLCSIEQELSTIGKPISKT----LDGKSKQR---PTGRSASAKHSGGGSS-GGSTSSSTRASPASTVRGGNSQSR---PLASNFSLDDITAQLEKASLSMDEAAKQTSESSSSSYSSAN---PPSNSHHRRTGSVGTVSDQEVRSIGHSSRSSVNSASASSMDSLDIRGQENET---QSQNQSQTSTEHVLLRRANGKTTRRHLDFTSQEGEVDQSTHSYLDRETSLILKNIAGKPSHLLTKEEQAAKAKAEKIRVALEKIKEAQVKKLVIRVHMSDESSKTMMVDERQTVRQLLDSLLDKSHCGYSPDWALVETIPELQMERIFEDHENLVENLLNWTRDSQNKLMFIERIEKYALFKNPQNYLLGR--KETSEMADRNKEALLEECFCGSSVSVPEIEGVLWLKEDGKKSWKKRYFLLRASGIYFVPKGKAKASRDLVCFLQLDHVNVYYGQDYRSKYKAPTDYCLALKHP---QIQKKSQYIKYLCCDDVRTLHQWVNGIRIAKYGKQLYVNYQEAMKRTEAAYDWSSLSSTSIKSGTSS--VSIPESQSNHSSQTDSGMSDGTSSSHARSQSVVSSIFSEAWKRGTQIEESTKARPESIRSTHSSHSSHSSHHVSQQQHLHAQQPHVHSILQSRGSVTQAPAQAPTQTLAQAPPQVAPAPPPPPPPPPPPPPPPISS---IPHHATPTMFAKYSTITRLQNASQATSHHKPQP---QIQQQVPPVPPP--SKPQSNNIPSGANIPPP-PPPPPPASMPPPGSAMAVLKLGPPAAAVIPQISPSPPSPPPPPPPPPIMPVQSQPQPPPPPIMPMQSQPLPPPPPITPMQSHNLPPPPPMQSHALPPPPPITPMQSHALPPPPPITPMQSHALPPPPPITPMQSHALPPPPPITPMQSHALPPPPPIMPMQSEPLPPPAQIMPMQSHPLPPPPPLVQMQSQPMPPPPPTVSFQSQPLPPPPPPLQANGLPPPPPLITNGLKQAFAHKFPSTPQDVLPPANQNNFPPPPPPPPPPPLAPTLPPYQHVTSTSNPPPPPPPPPPPPPAPIHLANQPAVLPKFFTGGFPPQKAPKPSCGILPVSPVAPALQPPPPPPPPPPPPPPAPLKNQPPPTLPKQHSLSKTLP-FSSQTSSVPSMVKQLASQFPVASPALTNQTDSLK------APQSPPAVKVKPKWQPVGQGQQQQRSPEFPPPPPDNALGFASPTPPPPPPPPLPPGPTPPPP------PPPPPLMSGSPIKKSPSGSSAGVKKPPPTPQRNSSVKYDASTEYQESR----KNLVSKFNPSSAS-----STTSTSSCSPSKELSAGPQAPPKPGKLNLA--NLPLALQN---------KFNQNRQSAADFPSPPPPENDFFPPPPIESDLP-PPPPLPGDLN-GVSPKVAVVNPQPQP------AWGKSSLKKTQPPASLRCNNTVRESPPLSPP-------SIHGGPIPHSPKG--TTQPNFLEDLNKTLKRK---------SSRVSGDKVDPVATMDDMVLPPPPPELLQDQQRLSGSGFMSGNISGYATLRRGPPPAPPKRDHSTKLTN--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8I6A272-1", "uniprot_id": "A0A8I6A272_RAT", "id": "A0A8I6A272-1", "name": "", "aln": "-----------------------------MEQLSDEEIDHGAEEDSDKEDQDLDKMFG-----------------------------AWLGELDRLTQSLDSDKPKEPVKRSPLRQETNMANFSYRFSIYNLNEALNQGETVDLDALMADLCSIEQELSSVGSGNSKR----QVTEPKVAQKLPASR-HTSKHG----TLRGVSSSSTRTTRPP---------------HANYSLDDITAQLEQASLSMDEAAQQSAVEDAK---------PPATNQHRRTASAGTVSDAEVRSVSNSSRSSITSA-ASSMDSLDIDKVTRPQELDLTAHQGKPITEHATSLSCPSKQAKHHSDFTEEQAQL--APHSYLDRETSLLLRNIAGKPSHLLTKEEQAAKLKAEKIRVALEKIKEAQVKKLVIRVHMSDDSSKTMMVDERQTVRQVLDNLMDKSHCGYSLDWSLVETISELQMERIFEDHENLVENLLNWTRDSQNKLIFMERIEKYALFKNPQNYLLGK--KETAEMADRNKEVLLEECFCGSSVTVPEIEGVLWLKDDGKKSWKKRYFLLRASGIYYVPKGKAKVSRDLVCFLQLDHVNVYYGQDYRNKYKAPTDCCLALKHP---QIQKKSQYIKYLCCDDARTLHQWVNGIRIAKYGKQLYTNYQEALKRTESAYDWTSLSSSSIKSGSSS--SSIPESQSNHSNQSDSGVSDTLPSGHIRSQSTVSSIFSEAWKRGTQLEES---------SKARMESMNRSYT--------SLMPPLSPQTKIITPYTASQPSPPLPP--------PPPPPPPPPPPPPPPPPPLPSQSAPSSGSAATMFVKYSTITRLQNAAQHSGTLFKSP----APSAMQPLPLASQSKAQIVVPPNGVIPPPPPPPPPP-----TPGSAMAQLKPVP--------CAPSLPQFSPQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PPPLKIHQVQHLPQAAPP--------------TPPAAPL------------------IPATVPPQAPPKPLVTIP----------PSASTKMVSPVVAQAVPP--TPAPPVPPTKKQPVFPVSHIPPTPPVQPTPHPPPTLPKQQSFGVKPP--PSPLSPVPSVVKQMASQFPPPPTPPPVDSQPLKPLPASVTPQSPPAVKAKPKWQPSSIPAPS---PDFPPPPPESSLVFPPPPPPAPVPPPPPPPPPPPPPPPVSPMASPTPDKGGSPGKKTSKMSSPGGKKPPPTPQRNSSIKSGSCAEHPEPKRPSVDSLVSKFAPPAES------------GSPSKETPPPPAAPPKPGKLHLSGVNLPGIHQQGILSAKPSVLSGRGKDAVVEFPSPP--SDSDFPPPPPEIELPLPPIEIPAVFSGNTSPKVAVVNPQPQL-------WSKTSVKKAPPPTRPKRNDSTRLTQADISE---QPAMTTVVPQVPTSPKSSLSVQPGFLADLNRTLQRKSITRHGSLSSSRMS--RAEPTATMDDMALPPPPPELLSDQQ-KAG--FGGSHISGYATLRRGPPPAPPKRDQNTKLSRDW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F2Z3U3-1", "uniprot_id": "F2Z3U3_MOUSE", "id": "F2Z3U3-1", "name": "", "aln": "-----------------------------MEQLSDEEIDHGAEEDSDKEDQDLDKMFG-----------------------------AWLGELDRLTQSLDSDKPKEPVKRSPLRQETNMANFSYRFSIYNLNEALNQGETVDLDALMADLCSIEQELSSIGSGNSKR----QVTEPKVPQKLPAGR-HTSKHG----TLRGPSSSSNRTTKPS---------------HANYSLDDITAQLEQASLSMDEAAQQSLVEDPK---------PLVTNQHRRTASAGTVSDAEARSISNSSRSSITSA-ASSMDSLDIDKVTRPQELDLTTHQGQPITE------------------------------------------------------EEQAAKLKAEKIRVALEKIKEAQVKKLVIRVHMSDDSSKTMMVDERQTVRQVLDNLMDKSHCGYSLDWSLVETISELQMERIFEDHENLVENLLNWTRDSQNKLIFMERIEKYALFKNPQNYLLGK--KETAEMADRNKEVLLEECFCGSSVTVPEIEGVLWLKDDGKKSWKKRYFLLRASGIYYVPKGKAKVSRDLVCFLQLDHVNVYYGQDYRNKYKAPTDCCLALKHP---QIQKKSQYIKYLCCDDARTLHQWVNGIRIAKYGKQLYTNYQEALKRTESAYDWTSLSSSSIKSGSSS--SSIPESQSNHSNQSDSGVSDTLPTGHIRSQSTVSSIFSEAWKRGTQLEES---------SKARMESMNRSYT--------SLMPPLSPQTKIITPYTASQPSPPLPP--------PPPPPPPPPPPPPPPPPPLPSQSAPSSGSAATMFVKYSTITRLQNAAQHSGTLFKSP----TPPAMQPLPLASQSKAQIVVPPNGVIPPPPPPPPPP-----TPGSAMAQLKPVP--------CAPSLPQFSPQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PPPLKIHQVQHLPQTAPP--------------TPPPAPP------------------ITATVPPQAPPKPLVTIP----------PSASTKTVSPVVAQAVPP--TPAPPVPPAKKQPVFPVSHIPPTPPVQPTPHPPPTLPKQQSFGVKPP--PSPLSPVPSVVKQIASQFPPPPTPPPVDSQPLKSLPASGTPQSPPAVKAKPKWQPSSIPVPS---PDFPPPPPESSLVFPPPPPPAPAPAPPPPPPPPPPPPPVPPTASPTPDKGGSPGKKTSKMSSPGGKKPPPTPQRNSSIKSGSCAEHPEPKRPSVDSLVSKFAPPAES------------GSPSKETPPPPAAPPKPGKLHLSGVNLPGIHQQGIVSAKASVLSGRGKDVVVEFPSPP--SDSDFPPPPPEIELPLPPIEIPAVFSGNTSPKVAVVNPQPQL-------WSKTSVKKAPPPTRPKRNDSTRLTQADISE---QPAMTTVVPQVPTSPKSSLSVQPGFLADLNRTLQRKSITRHGSLSSSRMS--RAEPTATMDDMALPPPPPELLSDQQ-KAG--FGGSHISGYATLRRGPPPAPPKRDQNTKLSRDW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q70E73-10", "uniprot_id": "RAPH1_HUMAN", "id": "Q70E73-10", "name": "Ras-associated and pleckstrin homology domains-containing protein 1", "aln": "-----------------------------MEQLSDEEIDHGAEEDSDKEDQDLDKMFG-----------------------------AWLGELDKLTQSLDSDKPMEPVKRSPLRQETNMANFSYRFSIYNLNEALNQGETVDLDALMADLCSIEQELSSIGSGNSKR----QITETKATQKLPVSR-HTLKHG----TLKGLSSSSNRIAKPS---------------HASYSLDDVTAQLEQASLSMDEAAQQSVLEDTK---------PLVTNQHRRTASAGTVSDAEVHSISNSSHSSITSA-ASSMDSLDIDKVTRPQELDLT-HQGQPITE------------------------------------------------------EEQAAKLKAEKIRVALEKIKEAQVKKLVIRVHMSDDSSKTMMVDERQTVRQVLDNLMDKSHCGYSLDWSLVETVSELQMERIFEDHENLVENLLNWTRDSQNKLIFMERIEKYALFKNPQNYLLGK--KETAEMADRNKEVLLEECFCGSSVTVPEIEGVLWLKDDGKKSWKKRYFLLRASGIYYVPKGKAKVSRDLVCFLQLDHVNVYYGQDYRNKYKAPTDYCLVLKHP---QIQKKSQYIKYLCCDDVRTLHQWVNGIRIAKYGKQLYMNYQEALKRTESAYDWTSLSSSSIKSGSSS--SSIPESQSNHSNQSDSGVSDTQPAGHVRSQSIVSSVFSEAWKRGTQLEES---------SKARMESMNRPYT--------SLVPPLSPQPKIVTPYTASQPSPPLPP--------PPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPP----TPPVMQ----SQSVKPQILVPPNGVVPPPPPPPPPP-----TPGSAMAQLKPAP--------CAPSLPQFSAP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PPPLKIHQVQHITQVAPP--------------TPPPPPP------------------IPAPLPPQAPPKPLVTIP----------APTSTKTVAPVVTQAAPP--TPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPP--PSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPS---PDFPPPPPESSLVFPPPPP-SPVPAPPPPPPP---------TASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAES------------GSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPP--SDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQ-------WSKMSVKKAPPPTRPKRNDSTRLTQAEISE---QPTMATVVPQVPTSPKSSLSVQPGFLADLNRTLQRKSITRHGSLSS-RMS--RAEPTATMDDMALPPPPPELLSDQQ-KAG--YGGSHISGYATLRRGPPPAPPKRDQNTKLSRDW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VWB7-1", "uniprot_id": "Q9VWB7_DROME", "id": "Q9VWB7-1", "name": "", "aln": "MDCGGIAAHQQQQLQQQQLHLLQQQLQQQHHQQQRQQQQHSLEEAATITNINLRGILVGGAASSAGVAGAAAGGATTTTTTTTAAGFVAGGDCPVIGAGAGAGVKLRRHSDRPLTPEAKQLSHTYRISMANLEDSQES----ELDQILGELSLLEAQISYTEASMLPA---MCAPSAGAQIAPPPGVTQLPGSAPTMVSMSASSSRSHSRTNSTIS-----------ADVSSCSSSGISENGHGLGLVLGGPGSAGMMVQPP---------PPGGMTMGITLGVVTPREPRTESPDNDSAFSDTVSLLSSESSASSNTSLQQQQQQQQQQHHQHQQHHQHQ-----------------------QQQQKPQLAGAEKLHHHGVHGQHGGQQSGANSITKADKIQLALHKLESAPIRRLFVKAFTSDGASKSLLVDERMGCGHVTRLLADKNHVQMQSNWALVEHLGDLQMERLFEDHELLVDNLMTWHSDAGNRVLFQQRPDKVTLFLRPELYLPGPQMAPGCQHDEQTRQMLLDEFFD--SHNQLQMDGPLYMKADPKKGWKRYHFVLRSSGLYYFPKEKTKNTRDLACLNLFHGHNVYTGLGWRKKWKSPTDYTFGFKAVGDSSLGKSCRSLKMLCAEDLPTLDRWLTAIRVCKYGKQLWDSHKSLLEDLCLSRDDAVSQSSFAASMRSESISSISSAVPSQCGSVSSAISSMSNSTSGRTSRASSSSSSGCLSDDNNAFDS-------EFTTGTIKRKPSMKPN-------LPLTTMTRQLKEVGEITICESAGGDAS---------------------------------SPERSGTLTRRHS--RRKSQESNGSGTLKRRP------IAVPVATVVKQTEPMGSASSTSSSSNSTPTPTPSICAKPPPGDSASLMCSST--------LSLDSLPPPPP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PPALDGSEDQDVYGSQLS----------------------------------------LASLPPPPPP------------------------------------------------EDVLAMNYAEPSSPSTPTPMSTPMIMPN-SNGSLPP--AVPAKPMKPAVKQAAGGLKAAP------------------PYKAPPDYVGPALLPG---------PPLPPPPPAQKKVS----------------------------------FADSPVLLRRKMCSPEPVLPQRSPSTTLSCHSSSSAG-----------------------------------SAYQTYAPGPMLPPRADVARLS---------------------SLSNGSSSEVTSPK----------RLQESASNPPRDFLKDLQRVMRKKWQVAQKCKAEP-------------ATTPHEVLGFRDFSNEDLLAAHN--------LNSGANSSHYYRETANVSHWVRKHYEYAHNALYENVHAQSAAAAG---VPGSGEATTPPLPPPP--------------------GNSVAAKKRPPPPPPKRSDKTHLTNRV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* . :: :*. ** : : :* :: . *: : . . . . . ** ::: . :**:*: *:::: :. :** ::.:*. :* ::* .. * . : . :* * : .. :. * ..:: : . . :. .. .. . * .. * : ...* :.* * . : ** .* . :. : . : **:**::**.*::.* :::*.::.. ** :**:::**** :: * **.* . :*:*** : :*****:***** **:**:.* *: *:::* :* :* :** .*: ** * .: ::.:: **:* * : . :::* *::* * **.**: :*:**:**:*:.** *:* :***.*: :. *** * .:*.*:*:*** : :* .: *..: :* **.:* *.:*:..**:.******: .::. :. : * : .*: * *. *:..: ..:... .*.:*. : *:. ** * . . ..: : . . : : : . . : : ::* * .: :: .. * :. . .. .*.*. **.: : : . : . .. **.* :. . . ** . . .. ..* : : * * . .. . *** .. : * ..* * * * :***** . ** . .. * :*. . * : : . *. : .:.. .*: . . :..** : . ** : : * *.: * . . : . :: . . :. : . . ***** .. .: :: ***.****...*:*: ", "identical_positions": 199, "similar_positions": 320, "identity": "11.58%" }, { "cls_id": "homologset.agr.RGD:1308388", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4A1W8-1", "uniprot_id": "MTP_RAT", "id": "D4A1W8-1", "name": "Microsomal triglyceride transfer protein large subunit", "aln": "----MILLAVLFLCFFSSYSASVKGHTTGLSLNNERLYKLTYSTEVFLDGGKGKLQDSVGYRISSDVDVVLLWRNPDGDDDQLIQVTITAVNVENAGQQRGEKSIFKGKSTPKIVGKDNLEALRRPMLLHLVRGKVKEFYSYENEPVGIENLKRGLASLFQMQLTSGTTNEVDISGDCKVTYQAQQDKVVKIKALDTCKIERSGFTTANQVLGVTSKATSVTTYKIED-SFVTAVVAEETRAFALNFLQTVAGKIVSKQKLELKTTEAGPRMVPGKQVAGVIKAIDSKYKAIPIVGQVLQS----VCKGCPSLAEHWQSIRKHLEPENLSNAEAVQSFLAFIQHLRTSRREEILQILKAEKKEVLPQLVDAVTSAQTPASLEAILDFLDFKSDSS---IILQERFLYACGFASHPDEELLQALLSKFKGSFASNDIRESVMIIIGALVRKLCQNEGCKLKAVVEAKKLILGGLEKPEKKEDTTMYLLALKNALLPEGIPLLLKYAEAGEGP-VSHLATTVLQRYDASFITDEVKKTLNRIYHQNRKVHEKTVRTTAAAVILKNNPSYMDVKNILLSIG--ELPKEMNKYMLTIVQDILHFEMPASKMIR-RVLKEMIVHNYDRFSKSGSSSAYTGYVERSPHAASTYSLDILYSGSGILRRSNLNIFQYIGKAELHGSQVVIEAQGLEGLIAATP-----------DEGEENLDSYAGMSAILFDVQLRPVTFFNGYSDLMSKMLS-ASGDPVSVVKGLILLIDHSQDIQLQSGLKANMDIQGGLAIDISGSMEFSLWYRESKTRVKNRVAVVITSDITVDSSFVKAGLESRAETEAGLEFISTVQFSQYPFLVCMQMDKAEAPLRQFETKYERLSTGRGYVSRRRK---ESLVPGCELPLHQENSEMCNVVFPPQPESGNSGGGWF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08601-1", "uniprot_id": "MTP_MOUSE", "id": "O08601-1", "name": "Microsomal triglyceride transfer protein large subunit", "aln": "----MILLAVLFLCFFSSYSASVKGHTTGLSLNNERLYKLTYSTEVFLDGGKGKPQDSVGYKISSDVDVVLLWRNPDGDDDQVIQVTITAVNVENAGQQRGEKSIFQGKSTPKIIGKDNLEALQRPMLLHLVRGKVKEFYSYENEPVGIENLKRGLASLFQMQLSSGTTNEVDISGDCKVTYQAQQDKVVKIKALDTCKIERSGFTTANQVLGVSSKATSVTTYKIED-SFVTAVLAEETRAFALNFQQTIAGKIVSKQKLELKTTEAGPRMIPGKQVAGVIKAVDSKYKAIPIVGQVLER----VCKGCPSLAEHWKSIRKNLEPENLSKAEAVQSFLAFIQHLRTSRREEILQILKAEKKEVLPQLVDAVTSAQTPDSLEAILDFLDFKSDSS---IILQERFLYACGFATHPDEELLRALLSKFKGSFASNDIRESVMIIIGALVRKLCQNEGCKLKAVVEAKKLILGGLEKPEKKEDTTMYLLALKNALLPEGIPLLLKYAEAGEGP-VSHLATTVLQRYDVSFITDEVKKTLNRIYHQNRKVHEKTVRTTAAAVILKN-PSYMDVKNILLSIG--ELPKEMNKYMLTVVQDILHFEMPASKMIR-RVLKEMAVHNYDRFSKSGSSSAYTGYVERSPRAASTYSLDILYSGSGILRRSNLNIFQYIGKAELHGSQVVIEAQGLEGLIAATP-----------DEGEENLDSYAGMSAILFDVQLRPVTFFNGYSDLMSKMLS-ASGDPVSVVKGLILLIDHSQDIQLQSGLKANMEIQGGLAIDISGSMEFSLWYRESKTRVKNRVAVVITSDVTVDASFVKAGVESRAETEAGLEFISTVQFSQYPFLVCMQMDKAEAPLRQFETKYERLSTGRGYVSRRRK---ESLVAGCELPLHQENSEMCNVVFPPQPESDNSGG-WF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P55157-1", "uniprot_id": "MTP_HUMAN", "id": "P55157-1", "name": "Microsomal triglyceride transfer protein large subunit", "aln": "----MILLAVLFLCFISSYSASVKGHTTGLSLNNDRLYKLTYSTEVLLDRGKGKLQDSVGYRISSNVDVALLWRNPDGDDDQLIQITMKDVNVENVNQQRGEKSIFKGKSPSKIMGKENLEALQRPTLLHLIHGKVKEFYSYQNEAVAIENIKRGLASLFQTQLSSGTTNEVDISGNCKVTYQAHQDKVIKIKALDSCKIARSGFTTPNQVLGVSSKATSVTTYKIED-SFVIAVLAEETHNFGLNFLQTIKGKIVSKQKLELKTTEAGPRLMSGKQAAAIIKAVDSKYTAIPIVGQVFQS----HCKGCPSLSELWRSTRKYLQPDNLSKAEAVRNFLAFIQHLRTAKKEEILQILKMENKEVLPQLVDAVTSAQTSDSLEAILDFLDFKSDSS---IILQERFLYACGFASHPNEELLRALISKFKGSIGSSDIRETVMIITGTLVRKLCQNEGCKLKAVVEAKKLILGGLEKAEKKEDTRMYLLALKNALLPEGIPSLLKYAEAGEGP-ISHLATTALQRYDLPFITDEVKKTLNRIYHQNRKVHEKTVRTAAAAIILNNNPSYMDVKNILLSIG--ELPQEMNKYMLAIVQDILRFEMPASKIVR-RVLKEMVAHNYDRFSRSGSSSAYTGYIERSPRSASTYSLDILYSGSGILRRSNLNIFQYIGKAGLHGSQVVIEAQGLEALIAATP-----------DEGEENLDSYAGMSAILFDVQLRPVTFFNGYSDLMSKMLS-ASGDPISVVKGLILLIDHSQELQLQSGLKANIEVQGGLAIDISGAMEFSLWYRESKTRVKNRVTVVITTDITVDSSFVKAGLETSTETEAGLEFISTVQFSQYPFLVCMQMDKDEAPFRQFEKKYERLSTGRGYVSQKRK---ESVLAGCEFPLHQENSEMCKVVFAPQPDS-TSSG-WF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IVV0-1", "uniprot_id": "MTP_DANRE", "id": "A0A0R4IVV0-1", "name": "Microsomal triglyceride transfer protein large subunit", "aln": "----MMPVAGLLLCVTAVLCTSALG--AGPRLDNGKLYRYSYSTEVGLNRPTGSPGGNVGFRISSDVDINLAWRNPEIQDEQLLQVKISNIQVESAGKHSRKNNIFHGSSAESILGKVRLEALQRPFLVLWKMGKIRSLYAQKAEPATVKNLKRGVASMLMMQLKSGKMSEADASGKCLVEYKVNKHQVIRTKHLETCKSQETGFTTHSPVLGISGKCAAETVITLEN-GIIKSADAKETHVLSINARHKAATKVLSRQSLTLKAIEAGPAEVAGKDVAGVVKALDDKFLSVGVIVEKTKP----KCKGCPNLMETWKAVRSQLEPNSLSKAEAPRSFLTLVHSLRKSSKSEILTVLQNCSKTALPQLVDAVTSAQTPSSLSAILEFLDFSKKDG---LILQERFLYACGFASHPTESMLQSLLEVSQGKIGSTEIKESVVIIMGALLRKLCLKGACDLPAVLKVKELLLAGPDSTQEESEVQMYLLALKNALLPEGIPVLAKYAESEVGA-YSTIAITALQRYDPALITAEVKKALNRIYHQNQRIYEKNVRAAAADVIMSSNPSYMEVKNLLLSIG--HLPHEMNKYMLSKIQDVLRFQMPAYKLVR-QVMKDMISHNYDRFSKTGSSSAYSGFMAETVDVTCTYNLDILYSGSGVLRRSNMNIYGQSNNALLHGLQVTIEAQGLESLIAATP-----------DEGEEELESFAGMSALLFDVQLRPVTFFKGYSDLMSKMFS-MSGDPINVVKGLILLTDHSQVIPLQSGLRASAEFQAGLSIDISGGMEFSLWYRESKTSVNNRGALVIIGNMTVDTDFVSAGVEVGFETEATLDFITTVQFSEYPFLVCMQMDKTTFPFRETVSKQEKLPTGQMFSRKRSR---DQVVPGSEFPLHQENSNMCKKVFEPAW----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VIH3-1", "uniprot_id": "MTP_DROME", "id": "Q9VIH3-1", "name": "Microsomal triacylglycerol transfer protein", "aln": "MENKNKKCLRTLLLLALFLGLLEDGKTALIAPNSQQIFKLQN-QVILQELGRDSSSAETSYTFETDLKINSVWS---GDEDQLLEVFISGSKVDASGKARSITRIP-----------------DRPFYISLVRGQPDKVIAHTSKDQSLLNLERGIASLLQLRLDASQEEELDVSGLCRVSYNVKSSTKVEKTKRDCSLWDLRVNYNPEEALGVTQQAQETVFYELSSEGTLLHAESQENHRLNLAAKPDVG--SFVKSSLILQHVSQGSEEVKQLQLGSLDKAIQSLLEWYRVFELESDVDGMISAIKEQTLEDQLKASLTELQSADVGKSSLALAYVKLIPLARITRQ-EQFEDLLTEHAEVLPQLVDLLGAVQTFDAHNATFGFLYKESETTSEQLDLLEKYLQSLAVATHPDRKIVEHLFGLLEQESIKKHLKLRESVIQTVATLTRQSGLDVEDPLLKEVRSYLLQGLTS----KEPTLYIRALQNLQDPATIEALLEHAQTGEAPNLSVAALQALKAFPLGSFNSSHRLQFESIFYQRKRRFDSSARTLALDIILSLRPTQEQLGNFLDYLASNDRQFEIKTYVLQKLRMLAEKCPRFRALFKSELVKRRHVNNYNVLGQKGLTTVLTRQLSQAP-AFNETLLSTQEVYQGILKRGSVEFLLHAGRSQASSFKLGIYTAGLGSLVGDGDSGDGNDAIPADDEFSEDEAVTAGMEISVQGAQLRPLVFFSGQTELMGHVWGGSASDSTPAYQATTLSQDNEHYIILTSGATLHWRVLGARSVDLNGKVGFSLWNRNAQTEIQQNTGSAVLGHLAVGFTYAKLVQDFSITHEPKLSLNADLDFYSG-IKLCMQLQRPEQLLKQTNVRSVFLQSVDRPYAKHVRSTLSHKTAGCTFALNQKNNEMCNLIFRDL-----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* . * : :. :::: : : .. ...: :.:::.: * :::*:::: :. :*: .: . * ** : *: .. : : : *::**:**:: :* :. .* * ** * * *:.:. :. . : . . . .**:: :. . :.. . : . ::*.: : : . :..* *: . *. : : ..: **::. :. . . .* : :: . *:. .:.::. :: :: * : : * : * .****** : :.** : .* : ** ... : * *::* : ..*:** ..::. *: : . ...:: :* . . . : :.:. :* * . .: :*: **:* * * * ::*:: .. * * .*: : :. . : :: *::*.:: .:...*: * :*:. *: :: *:* :. . *::.*:* :: : . :.: .::* :**: :.:.* ::. : : .: *. .*:*:*..::: ..: . :: * : ** .*:. ** .*: ***. : ..****:.**.* ::**.:: . :.*. . :. * *:.: : * ** . .. ::*:.* : **** *:::* :::. .: .::*. :.. : *. *.: : ::* . : :***::: ::: : * : :: : . .*. :.*:*:*.:**: :* ", "identical_positions": 134, "similar_positions": 331, "identity": "14.46%" }, { "cls_id": "homologset.agr.RGD:1308389", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D6H5-1", "uniprot_id": "ZDHC4_MOUSE", "id": "Q9D6H5-1", "name": "Palmitoyltransferase ZDHHC4", "aln": "MDFLVLFLFYLAFLLICVVLICIFTKSQR--LKAVVLGGAQVCSRVIPQCLQRAVQTLLHQLFHTRHPTFIVLHLLLQGLVYAEYTCEVFGYCRELEFSLPYLLLPYVLLSVNLVFFTLTCAANPGTITKANESFLLQVYKFDDVMFPKNSRCPTCDLRKPARSKHCRLCDRCVHRFDHHCVWVNNCIGAWNTRYFLIYLLTLTASAATIATVTAAFLLRLVTVSDLYQETYLDDVGHFQAVDTVFLIQHLFLAFPRIVFLLGFVIVLSMLLAGYLCFALYLAATNQTTNEWYKGDWAWCQRW-PLVAWSPSAEPRIHQNIHSHGFRSNLREIFLPATPSYKKKEK---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5FVR1-1", "uniprot_id": "ZDHC4_RAT", "id": "Q5FVR1-1", "name": "Palmitoyltransferase ZDHHC4", "aln": "MDFLVLFSFYLAFLLICVIMICIFTKSQR--LKAVVLGGAQVCARVTPQCFQRAVQTLLHQLFHTRHPAFLALHLLLQGLVYAEYTYEVFSYCRELEFSLPCLLLPYVLLSVNLVFFTLTCSTNPGTITKTNVLLLLQVYEFDEVMFPKNSRCSTCDLRKPARSKHCRVCDRCVHRFDHHCVWVNNCIGAWNTGYFLIYLLTLTASAATIAILSAAFLLRLVAVSNLYQETYLDDLGRFQAVDTGFLIQHLFLAFPRIIFLLGFVIVLSLLLAGYLCFALYLAATNQTTNEWYRGDWAWCQHW-PLVAWSPSAEPQIHQNIYSHGLWSNLQEVFIPATPSYKKKKR---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NPG8-1", "uniprot_id": "ZDHC4_HUMAN", "id": "Q9NPG8-1", "name": "Palmitoyltransferase ZDHHC4", "aln": "MDFLVLFLFYLASVLMGLVLICVCSKTHS--LKGLARGGAQIFSCIIPECLQRAVHGLLHYLFHTRNHTFIVLHLVLQGMVYTEYTWEVFGYCQELELSLHYLLLPYLLLGVNLFFFTLTCGTNPGIITKANELLFLHVYEFDEVMFPKNVRCSTCDLRKPARSKHCSVCNWCVHRFDHHCVWVNNCIGAWNIRYFLIYVLTLTASAATVAIVSTTFLVHLVVMSDLYQETYIDDLGHLHVMDTVFLIQYLFLTFPRIVFMLGFVVVLSFLLGGYLLFVLYLAATNQTTNEWYRGDWAWCQRC-PLVAWPPSAEPQVHRNIHSHGLRSNLQEIFLPAFPCHERKKQE--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QAM1-1", "uniprot_id": "ZDHC4_DANRE", "id": "F1QAM1-1", "name": "Palmitoyltransferase ZDHHC4", "aln": "MDFLTLFGIYVAVVLTCIALVCKYSGHQQTPLGQLVGAFTRIVSPCIPQWLQSICYRTMHRLFHQRNNFFLYLHLLLEVVVYGEFTYEVFGFCLDMGSSSLSLCVPYILLALKSCLFYLCCSRDPGTLTKSNLSAHLKIYQYDEKLFQQGMKCSTCQLIKPARSKHCRVCNRCVQRFDHHCVWVNNCIGAQNTRYFMLYLLSVCAMAGNIAVLTTDMLLQTVLRTGLLHAHYIDEQGIQQPAGPLFIIQHLFLTFPRIVFMLGFLVFVFFLLAGYCLFHFYLVLVNQTSNEWFKAKGHNCQHCHPYSGHNCRTSYNPFRGFYHRGILKNIGEIFWPLRPVQKKEN----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q04629-1", "uniprot_id": "SWF1_YEAST", "id": "Q04629-1", "name": "Palmitoyltransferase SWF1", "aln": "MSWNLLFVLLIGFVVL-ILLSPVFKSTWP-----FSTFYRNVFQPFLVDDQKYRWKLHLVPLFYTS----IYLYLVYTYHMRVESTIKNELFLLERILIVPIIILPPVALGILAMVSRAEDSKD-------HKSGSTEEYPYDYLLYYPAIKCSTCRIVKPARSKHCSICNRCVLVADHHCIWINNCIGKGN--YLQFYLFLISNIFSMCYAFLRLWYISLNSTSTLPRAVLTLTILCGCFTIICAIFTYLQLAIVKEGMTTNEQDKWYTIQEYMREGKLVRSLDDDCPSWFFKCTEQKDDAAEPLQDQHVTFYSTNAYDHKHYNLTHYITIKDASEIPNIYDKGTFLANLTDLI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.: ** : :. :: : : . . .: : : : **: : *:*: : * * : : : : :* : *.: . . : : . * :* :: :*.** : ******** :*: ** ****:*:***** * *: :*:: : . . : : * : :: :* *:: : : . : : :: .. ::: : * . .: : . * : ", "identical_positions": 45, "similar_positions": 78, "identity": "12.68%" }, { "cls_id": "homologset.agr.RGD:1308391", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZF35-1", "uniprot_id": "D3ZF35_RAT", "id": "D3ZF35-1", "name": "", "aln": "MKPIVPDSSGRAPPENE-PAVVKLEDSDNYDKREDTLWDPGPEAARLRFRCFRYEEAIGPQEALAQLRELCHQWLRPEVHSKEQILELLVLEQFLGALPSEIQARVQEQWPGSPEEAAALVDRLRWELDGPRKWVTVQVQGKEVLSEKMEPSSFQPRPQVKLQTPEAGSETTPGATQELPLDLQMKEETELMENPELLESEPLSAAQEAAATLLPKVAQGHGIALDQTSPHSDTEPDVPPWSEDPMPLWHEEVEGILSPGFTLQMDSITAEPDTVSPHLHVPWDLDMASLSGQMQSPTREGGFAHALVLPSDPGSEQDPACEDPCPSVGPALVATRWHAPRDRSQGHPSTGTGVMRGGRCDVCGKVFSQRSNLLRHQKIHTGERPFVCGECGRSFSRSSHLLRHQLTHTEERPFVCRDCGQGFVRSARLEEHRRVHTGEQPFRCAECGQSFRQRSNLLQHQRIHGDPPGPAPPVRSLAGVPEPPGPFPCSECCESFPRRAVLLEHQAVHTGDKSFGCVECGERFGRRSVLLQHRRVHSGERPFACAECGQSFRQRSNLTQHRRIHTGERPFACTECGKAFRQRPTLTQHLRVHTGEKPFACPECGQRFSQRLKLTRHQRTHTGEKPYRCSECGLGFTQVSRLTEHQRIHTGERPFACPECGQSFRQHANLIQHRRIHTGERPYACPECGKAFRQRPTLTQHLRTHRREKPFACQDCGRRFHQSTKLIQHQRIHSTE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P28698-1", "uniprot_id": "MZF1_HUMAN", "id": "P28698-1", "name": "Myeloid zinc finger 1", "aln": "MRPAVLGSPDRAPPEDEGPVMVKLEDSE--EEGEAALWDPGPEAARLRFRCFRYEEATGPQEALAQLRELCRQWLRPEVRSKEQMLELLVLEQFLGALPPEIQARVQGQRPGSPEEAAALVDGLRREPGGPRRWVTVQVQGQEVLSEKMEPSSFQPLPETEPPTPEPGPKTPPRTMQESPLGLQVKEESEVTEDSDFLESGPLAATQESVPTLLPEEAQRCGTVLDQIFPHSKTGPEGPSWREHPRALWHEEAGGIFSPGFALQLGSISAGPGSVSPHLHVPWDLGMAGLSGQIQSPSREGGFAHALLLPSDLRSEQDPTDEDPCRGVGPALITTRWRSPRGRSRGRPSTGGGVVRGGRCDVCGKVFSQRSNLLRHQKIHTGERPFVCSECGRSFSRSSHLLRHQLTHTEERPFVCGDCGQGFVRSARLEEHRRVHTGEQPFRCAECGQSFRQRSNLLQHQRIHGDPPGPGAKPPAPPGAPEPPGPFPCSECRESFARRAVLLEHQAVHTGDKSFGCVECGERFGRRSVLLQHRRVHSGERPFACAECGQSFRQRSNLTQHRRIHTGERPFACAECGKAFRQRPTLTQHLRVHTGEKPFACPECGQRFSQRLKLTRHQRTHTGEKPYHCGECGLGFTQVSRLTEHQRIHTGERPFACPECGQSFRQHANLTQHRRIHTGERPYACPECGKAFRQRPTLTQHLRTHRREKPFACQDCGRRFHQSTKLIQHQRVHSAE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:* * .*..*****:* *.:******: :: * :********************* *************:*******:****:**************.******* * ************ ** * .***:********:************** *:.: ***.*.:*.* : ** **.**:***:*: *:.::*** **:*:**:..****: ** * .*** ***.* *: *.* *.* .*****. **:****:**:.**:* *.:***********.**.****:***:*********:**** *****: **** .*****::***::**.**:*:**** **:*********************************.*************************** *****************************************************.. : .*.************ ***.****************************************************************************:*****************************************************:*.**************************************** ************************************************************:**:*", "identical_positions": 610, "similar_positions": 81, "identity": "82.88%" }, { "cls_id": "homologset.agr.RGD:1308392", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XIE6-1", "uniprot_id": "HIBCH_RAT", "id": "Q5XIE6-1", "name": "3-hydroxyisobutyryl-CoA hydrolase, mitochondrial", "aln": "-------MGQQFVWRLQSRFSSIR--RASVILQHLRMSKHTETA-EVLLERRGCAGVITLNRPKLLNALSLNMIRQIYPQLKKWERDPDTFLIIIKGAG-GKAFCAGGDIKALSEAKK-AGQTLSQDLFREEYILNNAIASCQKPYVALIDGITMGGGVGLSVHGQFRVATERSLFAMPETGIGLFPDVGGGYFLPRLQG------KLGYFLALTGFRLKGRDVHRAGIATHFVDSEKLHVLEEELLALKSPSAED-----VAGVLESYHAKSKMGQDKSIIFEEHMDKINSCFSAN------TVEQILENLRQ-----DGSPFAMEQIKVINKMSPTSLKITLRQLMEGSTKTLQEVLTMEYRLTQACMEGHD----FHEGVRAVLIDKDQTP------------------------------------------------------------KWKPADLKDVTDEDLNSYFKSL-GSRDLKF------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8QZS1-1", "uniprot_id": "HIBCH_MOUSE", "id": "Q8QZS1-1", "name": "3-hydroxyisobutyryl-CoA hydrolase, mitochondrial", "aln": "-------MGQPYAWRLLSRVSSFR--RASVILQHLRMSMHTEAA-EVLLERRGCGGVITLNRPKFLNALSLNMIRQIYPQLKTWEQDPDTFLIIIKGAG-GKAFCAGGDIKALSEAKK-ARQNLTQDLFREEYILNNAIASCQKPYVALIDGITMGGGVGLSVHGQFRVATERSLFAMPETGIGLFPDVGGGYFLPRLQG------KLGYFLALTGYRLKGRDVHRAGIATHFVDSEKLRVLEEELLALKSPSAED-----VAGVLESYHAKSKMDQDKSIIFEEHMDKINSCFSAN------TVEQIIENLRQ-----DGSPFAIEQMKVINKMSPTSLKITLRQLMEGSSKTLQEVLIMEYRITQACMEGHD----FHEGVRAVLIDKDQTP------------------------------------------------------------KWKPANLKDVTDEDLNSYFKSL-GSSDLKF------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6NVY1-1", "uniprot_id": "HIBCH_HUMAN", "id": "Q6NVY1-1", "name": "3-hydroxyisobutyryl-CoA hydrolase, mitochondrial", "aln": "-------MGQREMWRLMSRFNAFK--RTNTILHHLRMSKHTDAAEEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAG-GKAFCAGGDIRVISEAEK-AKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG------KLGYFLALTGFRLKGRDVYRAGIATHFVDSEKLAMLEEDLLALKSPSKEN-----IASVLENYHTESKIDRDKSFILEEHMDKINSCFSAN------TVEEIIENLQQ-----DGSSFALEQLKVINKMSPTSLKITLRQLMEGSSKTLQEVLTMEYRLSQACMRGHD----FHEGVRAVLIDKDQSP------------------------------------------------------------KWKPADLKEVTEEDLNNHFKSL-GSSDLKF------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q58EB4-1", "uniprot_id": "HIBCH_DANRE", "id": "Q58EB4-1", "name": "3-hydroxyisobutyryl-CoA hydrolase, mitochondrial", "aln": "-------MS-LIIFTSAQRLRSVC--RLQRIHGHMMSSK---AGSEVLFEKVGKAGVITLNRPKALNALTLNMIRHIYPQLKKWDKDSETDIVIIKGAG-EKAFCAGGDIRAIAEAGK-AGNLLSQVFFREEYILNNTIGTYQKPYVALINGITMGGGVGLSVHGQFRVATEKTLFAMPETGIGLFPDVGGGYFLPRLQG------KLGLFLALTGFRLKGRDVQRVGVATHFVQSEKIESLEKDLVDLKSPSISD-----VAQLLDSYQEQSHLDAEKPFVLQEQTEAIDRLFSAG------SVEEIVENLKK-----DGSAFALKQAETLAKMSPTSLKLTFRQIEEGARMSLQEVFMMEYRLSQACMNGHD----FYEGVRAVLIDKDQSP------------------------------------------------------------KWKPSTLAGVSEQFVDKCFSSL-DERDLKL------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q86BP1-1", "uniprot_id": "Q86BP1_DROME", "id": "Q86BP1-1", "name": "3-hydroxyisobutyryl-CoA hydrolase, mitochondrial", "aln": "MQGPIQRLVYTFGHRTCSQLPMIGGATISQTKPTTMALSVRQSSSSVLATESSNKGMIILNRPKALNAINLEMVRKIYKHLKKCEKS--KSLVIIKGTG-DKAFCAGGDVRALVEAGP-TDE--SKSFFREEYSTNALIGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQG------KLGLYLGLTGYRLRGADVYYSGIATHYCESSKIPDLETALLN--CPDADD-----VPELLQKYHSP----PEKPFSLQPVLEQINKNFSAD------SVEGILENLQN-----DGSEWAKKTLETLSKMSPTSMKVTFRQLELGSQLSLAQCLIMEYRLAVRHLERSD----FKEGVRALLIDKDQKP------------------------------------------------------------QWQPTKLADVTEEHVQWFFRKLPDTEELKL------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P28817-1", "uniprot_id": "HIBCH_YEAST", "id": "P28817-1", "name": "Small ribosomal subunit protein mS47", "aln": "--------MLRNTLKCAQLSSKYGFKTTTRTFMTTQPQLNVTDAPPVLFTVQDTARVITLNRPKKLNALNAEMSESMFKTLNEYAKSDTTNLVILKSSNRPRSFCAGGDVATVAIFNFNKEFAKSIKFFTDEYSLNFQIATYLKPIVTFMDGITMGGGVGLSIHTPFRIATENTKWAMPEMDIGFFPDVGSTFALPRIVTLANSNSQMALYLCLTGEVVTGADAYMLGLASHYVSSENLDALQKRLGEISPPFNNDPQSAYFFGMVNESIDEFVSPLPKDYVFKYSNEKLNVIEACFNLSKNGTIEDIMNNLRQYEGSAEGKAFAQEIKTKLLTKSPSSLQIALRLVQENSRDHIESAIKRDLYTAANMCMNQDSLVEFSEATKHKLIDKQRVPYPWTKKEQLFVSQLTSITSPKPSLPMSLLRNTSNVTWTQYPYHSKYQLPTEQEIAAYIEKRTNDDTGAKVTEREVLNHFANVIPSRRGKLGIQSLCKIVCERKCEEVNDGLRWK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . ** . :* ***** ***:. :* . :: *: :. . ::*:*.:. ::******: .: : :* :** * :.. * ::::.***********:* :*:*::. :**** **:*****. : ***: ::. :* *** : * *. *:*:*: .*.:: *: * * .: . :::. * :: : :: :. ::* *::**:: :*. :* : : . **:*:::::* : .: : . : : : * * *..: ****:: * : : *::. : * .: *: ", "identical_positions": 89, "similar_positions": 115, "identity": "17.52%" }, { "cls_id": "homologset.agr.RGD:1308393", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BG80-1", "uniprot_id": "FBX46_MOUSE", "id": "Q8BG80-1", "name": "F-box only protein 46", "aln": "MDRGSLLPFQLWCPRPFSKYSQNQPRPPSTALKPPVCPDTSSGTEPDHRPAHLESTPPAVAAEAPTSQPAPLLSTAASGDEGRVLLDTWYVIKPGNTKEKVAFFVAHQCGGSSRASSMKVKGHWGSDSSKAKRRRRCLEPTKAPPDQGGREGTPATEVTPTSSGDDVDLVSVAEMVALVEQRAALALQSYPRPSTPAPVVFVSADQGGPAKGLGSERRSGGGDCSRVAEAVAHFEAQRDSPPTKGLRKEERPGPGPGEVRIAFRISNVREPHSPDGNLPNGGGGRPGCAYPGSPGPGTRAKDKITCDLYQLISPSRDALPSNVEFLLARADEASEGETPAPTRPEDTPPAPPPPPARDCGASGFHVDVVVTGVVDACIFFGKDGTKNVKEETVCLTVSPEEPPPPGQLFFLQSRGPEGPPEPPPADIPSTVPGPDDSEGTTDTSLCRLYRHVSHDFLEIRFKIQRLLEPRQYMLLLPEHVLVKIFSFLPTRALAALKCTCHHFKGIIEAFGVRATDSRWSRDPLYRDDPCKQCRKRYEKGDVSLCRWHPKPYHHDLPYGRSYWMCCRRADRETPGCRLGLHDNNWVLPCNGVGGGRAGREEGR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4KLY2-1", "uniprot_id": "FBX46_RAT", "id": "Q4KLY2-1", "name": "F-box only protein 46", "aln": "MDRGSLLPFQLWCPRPFSKYSQNQPRPPSATLKPPVCPDTSSGTEPDHRPAHLESTPPALAAEAPTSQHAPLLSTAASGDEGRVLLDTWYVIKPGNTKEKVAFFVAHQCGGGSRASSMKVKGHWGSDSSKAKRRRRCLEPTKAPPDQGGQEGTPATEVAPTSSGDDVDLLSVAEMVALVEQRAALALQSYPRPSTPAPVVFVSAEQGGPAKGLGSERRSGGGDCSRVAEAVAHFEAQRDSPPTKGLRKEERPGPGPGEVRIAFRISNVREPQSPDGSLANGGGGRPACPYPGSPGPGTRAKDKITCDLYQLISPSRDALPSNVEFLLARADEASEGETPAPARPEDTPPAPPPPPARDCGASGFHVDVVVTGVVDACIFFGKDGTKNVKEETVCLTVSPEEPPPPGQLFFLQSRGPEGPPEPPPADTASKVPGPEDSEGTTDTSLCRLYRHVSHDFLEIRFKIQRLLEPRQYMLLLPEHVLVKIFSFLPTRALAALKCTCHHFKGIIEAFGVRATDSRWSRDPLYRDDPCKQCRKRYEKGDVSLCRWHPKPYHHDLPYGRSYWMCCRRADRETPGCRLGLHDNNWVLPCNGVGGGRAGREEGR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PJ61-1", "uniprot_id": "FBX46_HUMAN", "id": "Q6PJ61-1", "name": "F-box only protein 46", "aln": "MDRGSLLPFQLWCPRPFGTYSQNQPRPPSAALKPSACPEPGGGAEPDHGPAHSENTPPALATEVPASQPAPLLSAAAAGDEGRVLLDTWYVIKPGNTKEKVAFFVAHQCGGGSRASSMKVKGHWGSDSSKAKRRRRCLDPTKAPPDPGGREGPPAAEEGPASAGEDVDLLSVAEMVALVEQRAALALQSYPRPTTPAPVVFVSAEQGGPAKGVGSERRSGGGDCSRVAEAVAHFEAQRDSPPTKGLRKEERPGPGPGEVRIAFRISNGREPRAPDSGLPSGGGGRPGCAYPGSPGPGARAKDKITCDLYQLISPSRDALPSNVEFLLARADEASEGDSPAPARPEDTPPAPPPPPARDCGASGFHVDVVVTGVVDECIFFGKDGTKNVKEETVCLTVSPEEPPPPGQLFFLQNRGPDGPPEPPPADSPATAPGPDDAEGTADTSLCRLYRHVSHDFLEIRFKIQRLLEPRQYMLLLPEHVLVKIFSFLPTRALAALKCTCHHFKGIIEAFGVRATDSRWSRDPLYRDDPCKQCRKRYEKGDVSLCRWHPKPYHHDLPYGRSYWMCCRRADRETPGCRLGLHDNNWVLPCNGPGGGRAGREEGR", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****************..**********::***..**:...*:**** *** *.****:*:*.*:** *****:**:*********************************.**************************:******* **:**.**:* *:*:*:****:***********************:**********:*******:****************************************************** ***::**..*..******.*.********:**************************************::***:********************************* ************************************.***:********* .:..***:*:***:****************************************************************************************************************************************************** ***********", "identical_positions": 542, "similar_positions": 51, "identity": "89.88%" }, { "cls_id": "homologset.agr.RGD:1308395", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "B3DMA0-1", "uniprot_id": "P5I11_RAT", "id": "B3DMA0-1", "name": "Tumor protein p53-inducible protein 11", "aln": "MAAKQPPPLMKKHSQTDLVSRLKTRKILGVGGEDDDGEVHRSKISQVLGNEIKFAVREPLGLRVWQFLSAMLFSSVAIMALALPDQLYDAVFDGAEVTSKTPIRLYGGALLSISLIMWNALYTAEKVIIRWTLLTEACYFGVQSLVVTATLAETGLMSLGTLLLLASRLLFVIVSIYYYYQVGRKPKKV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q4QQM4-1", "uniprot_id": "P5I11_MOUSE", "id": "Q4QQM4-1", "name": "Tumor protein p53-inducible protein 11", "aln": "MAGKQPPPLMKKHSQTDLVSRLKTRKILGVGGEDDDGEVHRSKISQVLGNEIKFAVREPLGLRVWQFLSAMLFSSVAIMALALPDQLYDAVFDGAEVTSKTPIRLYGGALLSISLIMWNALYTAEKVIIRWTLLTEACYFGVQSLVVTATLAETGLMSLGTVLLLASRLLFVIVSIYYYYQVGRKPKKV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14683-1", "uniprot_id": "P5I11_HUMAN", "id": "O14683-1", "name": "Tumor protein p53-inducible protein 11", "aln": "MAAKQPPPLMKKHSQTDLVSRLKTRKILGVGGEDDDGEVHRSKISQVLGNEIKFTIREPLGLRVWQFVSAVLFSGIAIMALAFPDQLYDAVFDGAQVTSKTPIRLYGGALLSISLIMWNALYTAEKVIIRWTLLTEACYFGVQFLVVTATLAETGLMSLGILLLLVSRLLFVVISIYYYYQVGRRPKKA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PA32-1", "uniprot_id": "A0A8M9PA32_DANRE", "id": "A0A8M9PA32-1", "name": "Tumor protein p53-inducible protein 11", "aln": "MATKPHPPLMKKHSQTDLVSRLKTRKILGVGGEDDDGEVHRSKISQMLGNEIKFAVREPVGLRLWILFSAVVFTVMALMALAFPNQLYEVVFDQEQTVTSVSIRLYGGAILSLSLIMWNGLYTAEKVIIQWTLLSEACYFAIQFLVTSVTLVELGSLPNAAILLLLSRIFFLTVTLSYYYHLGRRPKKI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** * ****************************************:*******::***:***:* :.**::*: :*:****:*:***:.*** :..:...*******:**:******.*********:****:*****.:* **.:.**.* * :. . :*** **::*: ::: ***::**:*** ", "identical_positions": 126, "similar_positions": 47, "identity": "66.67%" }, { "cls_id": "homologset.agr.RGD:1308396", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZKI9-1", "uniprot_id": "D3ZKI9_RAT", "id": "D3ZKI9-1", "name": "", "aln": "MGLGPRSAHKARRQFSGAGRRGRAARGSGRPPPGRDGCPQLPAAARAEQAPEALP-HLSPEALGYFRRALSALKVAP-DAAEERELMARNILKEVEAQALALATNRTGSEMLQELLGFSPLKPLCRVWIALRPNLRFVACHRCGVHVLQSALLQLPRLLRSPAEADEEEEGED--GPSQTLEELVLGLAAEVCDDFLFFCGDTHGSFVVRTLLQVLGGTLLESERVKPRGSQSSETQRTSARECKPTD-------FEVPKTFLNRLQDLSACFLK----------DIAVFITDKISSFCLQVALQVLHHKLPQHCAHLCDAVIDYLSSRNSSAGGSP-----LLLFLRDQTSSRLLEQVLLVLEPERLQRLFKNHFQGQLYSLAEHPIANFPLQRLLDAVTSPELLSLVFEELSPALEAVLARGHPGVVVALVEACRRVGAHQAQVLQLLFEAFHCAEPPSRQVACVPLFASLLAYEVYYELMEEEGAVPAEHQVEMASARPLREVTVLGSLLLQHLLYFSNPGLVLRSLSALTGPQLLTLAQSPAGSHVFDAILTSPSVTHKQRRRVLKTLKGQYVALACSRHGSRVFDAIWSGAALG--ARKEIAAELGEQNQELIQDPFGHHVARNVALTTFLKRRQAWE----QQQNSVAKRRRALNSILGD---------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BMC4-1", "uniprot_id": "NOP9_MOUSE", "id": "Q8BMC4-1", "name": "Nucleolar protein 9", "aln": "MGLGPRSAHKARRQFSGAGRRGRAARGSGRPPPGRDGYPRLPAAARAEQAPEALP-HLSPEALGYFRRALSALKVAP-DAAEERELMARNILKEVEAQALALATNRTGSEMLQELLGFSPLKPLCRVWAALRPNLRFVACHRCGVHVLQSALLQLPRLLRRPAEAEEEEEEEEEGGPSQTLEELVLGLAAEVCDDFLFFCGDTHGSFVVRTLLQVLGGTLLESERGKPRGSQSSETQRTSARECKPTD-------FEVPKTFLNRLQDLSACFLK----------DIAVFITDKISSFCLQVALQVLHQKLPQHCAHLCDAVIDYLSSRNSSADGSP-----LLLFLRDQTSSRLLEQVLLVLEAERLQRLYKDHFQGQLCSLAEHPIANFPLQRLLDAITSPELLSLVFEELSPALEMVLAQGHPGVVVALVEACRRVGTHQAQVLQLLFEAFHCAEPPSRQAACVPLFAALLAYEVYYELMEEEGAVPAEHQVEMATARALREVTVLGSLLLQHLLYFSNPGLVLRSLSALTGPQLLTLAQSPAGSHVFDAILSSPSVTHKQRRRVLKTLKGQYVALACSRHGSRVLDAIWSGAALG--ARKEIAAELGEKNQELIQDPFGHHVARNVALTTFLKRREAWE----QQQSTVAKRRRALSSILED---------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86U38-1", "uniprot_id": "NOP9_HUMAN", "id": "Q86U38-1", "name": "Nucleolar protein 9", "aln": "MGQGPRSPHKVGRRFPAGGKRGRGAKGSGRPLPGRKRQPWPPPDGRSEPAPDSHP-HLSPEALGYFRRALSALKEAP-ETGEERDLMVHNIMKEVETQALALSTNRTGSEMLQELLGFSPLKPLCRVWAALRSNLRTVACHRCGVHVLQSALLQLPRLLGSAAEEEEEEEEDGKDGPTETLEELVLGLAAEVCDDFLVYCGDTHGSFVVRTLLQVLGGTILESERARPRGSQSSEAQKTPAQECKPAD-------FEVPETFLNRLQDLSSSFLK----------DIAVFITDKISSFCLQVALQVLHRKLPQFCAHLCNAVIGYLSTRGSSVDGSP-----LLLFLRDQTSSRLLEQVLLVLEPPRLQSLFEEHLQGQLQTLAAHPIANFPLQRLLDAVTTPELLSPVFEELSPVLEAVLAQGHPGVVIALVGACRRVGAYQAKVLQLLLEAFHCAEPSSRQVACVPLFATLMAYEVYYGLTEEEGAVPAEHQVAMAAARALGDVTVLGSLLLQHLLHFSTPGLVLRSLGALTGPQLLSLAQSPAGSHVLDAILTSPSVTRKLRRRVLQNLKGQYVALACSRHGSRVLDAIWSGAALR--ARKEIAAELGEQNQELIRDPFGHHVARNVALTTFLKRREAWE----QQQGAVAKRRRALNSILED---------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P47077-1", "uniprot_id": "NOP9_YEAST", "id": "P47077-1", "name": "Nucleolar protein 9", "aln": "--MGKTKTRGRRHQDKQRKDEFEPSSNSAKEHIQQEESTYNDEAEIKETQPQMFFGVLDREELEYFKQAESTLQLDAFEAPEEKFQFVTSIIEEAKGKELKLVTSQITSKLMERVILECDETQLKDIFQSFNGVFFGLSCHKYASHVLETLFVRSAALVERELLTPSFDNNEKE-GPYVTMENMFLFMLNELKPHLKTMMNHQYASHVLRLLILILSSKTLPN-STKANSTLRSKKSKIARKMIDIKDNDDFNKVYQTPESFKSELRDIITTLYKGFTNGAESRSDISQSTITKFREYSVDKVASPVIQLIIQVEGIFDRDRSFWRLVFNTADEKDPKEESFLEYLLSDPVGSHFLENVIGSARLKYVERLYRLYMKDRIVKLAKRDTTGAFVVRALLEHLKEKDVKQILDAVVPELSMLLNSNMDFGTAIINASNKQGGYLRDDVIAQLIQKYYPEKSDAKNILESCLLLS--------------ASTLGNTRDDWPTAEERRRSVFLEQLIDYDDKFLN---ITIDSMLALPEERLIQMCYHGVFSHVVEHVLQTTRVDIIKRKMLLNILSKESVNLACNVYGSHIMDKLWEFTAKLTLYKERIARALVLETEKVKNSIYGRQVWKNWKLELYVRKMWDWKKLIKEQEFEIFPNSKPLQPKPEKHSRERNNSKEGSAFKKQKHYR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ..: :: . . : .*.: :. . * *: *. * * **::* *:*: . :: **: :. .*::*.: : * * *.: *::::.:: . . * :: ::. : ::**: . ***:: ::: . *: . :: : ** *:*::.* : *: .: .. :.*.*:* *: :*... * . :...: *: .: . : . * ::.*::* ..*:*: : : * **: *: .:.:: . . : : : * . : : .:: .* * :* * ..*::**:*: . :: *:. :::.:: .** : :. : * * . : :. ::: : * *. :* . . : : :: * : .*: *:: :: :. ::: *: : .:. .: : .:*. ..* .*: . .:. :.: *: **. :*: :. . ***.: :* :. * *: :*: *. : * ***. :**:::* :*. :* ::.** * :.::: .. :*::* :* * :::: *: :*: : . :.*.. . ", "identical_positions": 104, "similar_positions": 251, "identity": "15.14%" }, { "cls_id": "homologset.agr.RGD:1308398", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q6P7C4-1", "uniprot_id": "LRC26_RAT", "id": "Q6P7C4-1", "name": "Leucine-rich repeat-containing protein 26", "aln": "MRGSFFSRLPPQLSLLLLLLLLLSWRRVWTQEHIGTDPSKSPVAPVCPEACSCSPGGKANCSALALPAVPAGLSWQVRSLLLDRNRVSTLPPGAFADAGALLYLVLRENRLRSVHARAFWGLGVLQRLDLSSNQLETLSPGTFTPLRALSFLSLAGNRLALLEPSILGPLPLLRVLSLQDNSLSALEAGLLNSLPALDVLRLHGNPWACSCALRPLCTWLRKHPRPTSETETLLCVSPKLQTLNLLTDFPDNAFKQCTQSLAARDLAVVYALGPASFLASLAICLALGSVLTACGARRRRRR-TTVRHLIRRQP----DPEGPASLEDVGSPTTTAIQA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91W20-1", "uniprot_id": "LRC26_MOUSE", "id": "Q91W20-1", "name": "Leucine-rich repeat-containing protein 26", "aln": "MRGSFFSRLPPQLS----LLLLLSLRRVWTQEDIGTAPSKSPVAPECPEACSCSLGGKANCSALALPAVPADLSWQVRSLLLDHNRVSALPPGAFANAGALLYLDLRENRLRSVHARAFWGLGVLQWLDLSSNQLETLPPGTFAPLRALSFLSLAGNRLALLEPSILGPLPLLRVLSLQDNSLSAIEAGLLNNLPALDVLRLHGNPWTCNCALRPLCTWLRKHPRPASETETLLCVSPRLQTLSLLTAFPDAAFKQCTQSLAARDLAVVYALGPVSFLASLAICLALGSVLTACGARRRRRRRTTVRHLLRRQL----DPEGPPSLEDAGSPVTAAIQA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q2I0M4-1", "uniprot_id": "LRC26_HUMAN", "id": "Q2I0M4-1", "name": "Leucine-rich repeat-containing protein 26", "aln": "MRGPSWSRPRPLLL----LLLLLSPWPVWAQVSATASPSGSLGAPDCPEVCTCVPGGLASCSALSLPAVPPGLSLRLRALLLDHNRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLEALAPGTFAPLRALRNLSLAGNRLARLEPAALGALPLLRSLSLQDNELAALAPGLLGRLPALDALHLRGNPWGCGCALRPLCAWLRRHPLPASEAETVLCVWPGRLTLSPLTAFSDAAFSHCAQPLALRDLAVVYTLGPASFLVSLASCLALGSGLTACRARRRRLRTAALRPPRPPDPNPDPDPHGCASPADPGSPAAAAQA-", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***. :** * * ****** **:* : ** * ** ***.*:* ** *.****:*****..** ::*:****:*** :*******.**** * **** *:***.*******.** ****:****:*.****:***** ********* ***: **.***** ******.*:*: .***. *****.*:*:**** *.*******:***:** *:**:**:*** * **. ** *.* **.:*:*.** *******:***.***.*** ****** **** ***** * :::* : **.* .* * ***.::* ", "identical_positions": 212, "similar_positions": 57, "identity": "62.54%" }, { "cls_id": "homologset.agr.RGD:1308399", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AG20-1", "uniprot_id": "A0A8I6AG20_RAT", "id": "A0A8I6AG20-1", "name": "", "aln": "MAAVRPGSLITYQLSSVPLQMLFHLSGLYYALYFLATLLMIVYKSQVFSYPSNCLVLDLVLLLLMGIFEVAQLYLGTQGNLTEAEVPLAASLAFTAVSGLLSVHFLLWQTLVLWMDSVLSTVLLVLHGLEAGLQVVVIADFIR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D3H0-1", "uniprot_id": "TMM80_MOUSE", "id": "Q9D3H0-1", "name": "Transmembrane protein 80", "aln": "--------------------MLFHLSGLYSALYFLATLLMIVYKSQVFSYPCNCLALDLVLLLLMGILKVAQLYLGTKGNLMEAEVPLAASLAFTAVGGLLSVHFLLWQTLVLWMDSVLSTVLLVLHGLEAGLQVVVIADFIR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96HE8-1", "uniprot_id": "TMM80_HUMAN", "id": "Q96HE8-1", "name": "Transmembrane protein 80", "aln": "MAAPRRGRGSSTVLSSVPLQMLFYLSGTYYALYFLATLLMITYKSQVFSYPHRYLVLDLALLFLMGILEAVRLYLGTRGNLTEAERPLAASLALTAGTALLSAHFLLWQALVLWADWALSATLLALHGLEAVLQVVAIAAFTR", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***:*** * ***********.********* . *.***.**:****::..:*****:*** *** *******:** .***.******:**** * .**:.**.****** ****.** * *", "identical_positions": 89, "similar_positions": 21, "identity": "62.24%" }, { "cls_id": "homologset.agr.RGD:1308400", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P69478-1", "uniprot_id": "CHSTB_RAT", "id": "P69478-1", "name": "Carbohydrate sulfotransferase 11", "aln": "MKPALLEVMRMNRICRMVLATCLGSFILVIFYFQSMLHPVMRRNPFGVDICCRKGSRSPLQELYNPIQLELSNTAILHQMRRDQVTDTCRANSAMSRKRRVLTPNDLKHLVVDEDHELIYCYVPKVACTNWKRLMMVLSGRGK-YSDPMEIPANEAHVSANLKTLNQYSIPEINHRLK-SYMKFLFVREPFERLVSAYRNKFTQKYNTS--FHKRYGTKIIRRQRKNATQEALRKGDDVKFEEFVAYLIDPHTQREEP--FNEHWQTVYSLCHPCHIHYDLVGKYETLEEDSNYVLRLAGVSGYLKFPTYAKSTRTTDEMTTEFFQNISAEHQTQLYEVYKLDFLMFNYSVPNYLKLD--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JME2-1", "uniprot_id": "CHSTB_MOUSE", "id": "Q9JME2-1", "name": "Carbohydrate sulfotransferase 11", "aln": "MKPALLEVMRMNRICRMVLATCFGSFILVIFYFQSMLHPVMRRNPFGVDICCRKGSRSPLQELYNPIQLELSNTAILHQMRRDQVTDTCRANSAMSRKRRVLTPNDLKHLVVDEDHELIYCYVPKVACTNWKRLMMVLSGRGK-YSDPMEIPANEAHVSANLKTLNQYSIPEINHRLK-SYMKFLFVREPFERLVSAYRNKFTQKYNTS--FHKRYGTKIIRRQRKNATQEALRKGDDVKFEEFVAYLIDPHTQREEP--FNEHWQTVYSLCHPCHIHYDLVGKYETLEEDSNYVLQLAGVSGYLKFPTYAKSTRTTDEMTTEFFQNISAEHQTQLYEVYKLDFLMFNYSVPNYLKLD--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NPF2-1", "uniprot_id": "CHSTB_HUMAN", "id": "Q9NPF2-1", "name": "Carbohydrate sulfotransferase 11", "aln": "MKPALLEVMRMNRICRMVLATCLGSFILVIFYFQSMLHPVMRRNPFGVDICCRKGSRSPLQELYNPIQLELSNTAVLHQMRRDQVTDTCRANSATSRKRRVLTPNDLKHLVVDEDHELIYCYVPKVACTNWKRLMMVLTGRGK-YSDPMEIPANEAHVSANLKTLNQYSIPEINHRLK-SYMKFLFVREPFERLVSAYRNKFTQKYNIS--FHKRYGTKIIKRQRKNATQEALRKGDDVKFEEFVAYLIDPHTQREEP--FNEHWQTVYSLCHPCHIHYDLVGKYETLEEDSNYVLQLAGVGSYLKFPTYAKSTRTTDEMTTEFFQNISSEHQTQLYEVYKLDFLMFNYSVPSYLKLE--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7T3S3-1", "uniprot_id": "CHSTB_DANRE", "id": "Q7T3S3-1", "name": "Carbohydrate sulfotransferase 11", "aln": "MKQTILDLMRMSRICRMVLATCLGSFILVIFYFQSMFQPVMRRNPFAAEGCCRKGSRNALQELYNPTQAEFSAAAVLHQARRDQVAETCRAHSASSRKRRVLTPSDLKHLVVDEDHELIYCYVPKVACTNWKRVMMVLSGRGK-YSNPMEIPSNEAHVPSNLKTLNQYSIPDINHRLK-NYLKFLFVREPFERLVSAYRNKFTLRYNTS--FHKRYGTKIVRRYRKNATTEALQSGADVKFQEFAEYLVDPGTQREAP--LNEHWQTVYSLCHPCHIHYDLVGKYETLEDDANYVLKLVGEGDSLRFPSFAKSTRTTDQMAAMFFGNISSQQQSQLYQLYKLDYLMFNYSIPSYLKLQ--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VJG5-1", "uniprot_id": "Q9VJG5_DROME", "id": "Q9VJG5-1", "name": "Carbohydrate sulfotransferase", "aln": "----------MDQLVWLSFCISIGFSLLGNFSTGLPFEDGNNNN-------------------VKITRRSLELTQTINIQRQEFMQRQCELLGDHTQTLEDLSELQMDHMIVDKEHKLLYCYVPKVACTNWKRVLMMLTNKWHNGTDPLQIPGSLAHSVGMFTKLYDLSEAEQQQVLSDEYTRFILVRHPLERLLSAYRNKLEGDSPSARYFQSRVGRQIVKELRPGASNNSLERGDDVSFGEFIQYLVTPELSRANQSDYNEHWEVIAKLCNPCVMKYNVVGKYDTLLDDSALALYLAG-ADNLTFPTGHKPSSTRANLR-NYFDPLPIGAIRKLYDIYEDDFRLFDYALDEVLGFEFG", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.:: : :. .:* :* * :. ..* : : .:. : :: *:: : *. . ::. . *: ::.*::**::*:*:**************::*:*:.: : ::*::**.. ** . :..* : * .: :: *. .* :*::**.*:***:******: : *:.* * :*::. * .*: ::*. * **.* ** **: * .* ****:.: .**:** ::*::****:** :*: .* *.* .. * **: *.: * :: :* :. :**::*: *: :*:*:: . * :: ", "identical_positions": 100, "similar_positions": 122, "identity": "27.78%" }, { "cls_id": "homologset.agr.RGD:1308401", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D925-1", "uniprot_id": "LYZL4_MOUSE", "id": "Q9D925-1", "name": "Lysozyme-like protein 4", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQLYLVLLLISYLLTPIGASILGRCTVAKMLYDGGLNYFEGYSLENWVCLAYFESKFNPSAVYEDPQDGSTGFGLFQIRDNEWCG---HGKNLCSVSCTALLNPNLKDTIQCAKKIVKGKH-----GMGAWPIWSKNCQLS--DVLDRWLDGCDL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4ABW7-1", "uniprot_id": "LYZL4_RAT", "id": "D4ABW7-1", "name": "Lysozyme-like protein 4", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQLYLVLLLISYLLTPIGASILGRCVVAKKLYDGGLNYFEGYSLENWVCLAYFESKFNPSAVYENSRDGSTGFGLFQIRDNEWCD---HGKNLCSVSCTALLNPNLKDTIECAKKIVKGKQ-----GMGAWPVWSRNCQLS--DILDRWLDGCEL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96KX0-1", "uniprot_id": "LYZL4_HUMAN", "id": "Q96KX0-1", "name": "Lysozyme-like protein 4", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKASVVLSLLGYLVVPSGAYILGRCTVAKKLHDGGLDYFEGYSLENWVCLAYFESKFNPMAIYENTREGYTGFGLFQMRGSDWCGD--HGRNRCHMSCSALLNPNLEKTIKCAKTIVKGKE-----GMGAWPTWSRYCQYS--DTLARWLDGCKL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VSA5-1", "uniprot_id": "Q9VSA5_DROME", "id": "Q9VSA5-1", "name": "lysozyme", "aln": "MLRWPVVCLLLPLLATAKIFDRCELANLLQHRFGLPAAQVATLVCIAQHSSDFNTAAFGGGVGLGGGSHGLFQISDVYWCSPPGQGKGCGLSCSRLRDDDIADDVLCVRKIYAEHQRISGDGFTAWQAYDAYCRQDANSYVAGCGGPGSSALSVAASYHKPQQVQVHSYPVQQYHQVAQIQPQGKIYSRCELAQELYYQHKLPMPQIPTWVCIAQHESSFNTAAVGRLNADGSADHGLFQISDLFWCTHEQRAGKGCHATCNQFLDSSIGDDVQCIRRIHQEHTQISGDGFNAWTVYKRNCLNQHYEQIAACFAKPPAHQPQHHPNAIAGGPVKSKVSYAYQYGQVQVHQTPIAPAVNQYYRPPQPSPVLSYQTNVAAYSGNPFLRPRPVNPPRQHPNAIGVPLKNQTPANPFYIHKQQTQYQPQYQTHFQTHYQRTGKVYNRCELAQELYFSHKFPMQDLATWVCIAEHESSFNTTAVGRLNADGSADHGLFQISDLYWCTHNDGGGKGCHIDCNRLLDSDITDDVKCVRTIHEEHTRISGDGFTAWTVYNGHCRQKTRADVANCFDGKDLPAEVAKPSKGNELVKKTSPTPKAKIYNRCELAKELYHR--HKFPMREIPTWVCIAEHESSFNTAAVGKLNADGSEDHGLFQISDIYWCTHDQTSGKACHIECDRLLDSDISDDVQCIRTIHEEHTRLSGDGFNAWTVYNGHCRNQNLAKLSDCFDGNEISEADKTSHYGERPQVMPHQSVPQKPQHKTATIQEYAGNPFLQNLQAAKPPQPTLNKNKLTNNVVAPKEQKTNKLYATNPFFNGQVQSKPPPTQGAPVYSTKKPNYDHNPFLKAPGSVTPSVKPSHASQEVKLHDSTSYAQNPFLSLLGKPIVPAQAPIKPQSKPPSPSKSTQLVSRPYVSSDSFRNEVIKFTATSAAVATTASFTKQSVTTTTRKPQTASTTKPVSTTAKTTSLPLWSWQTSTTAKPTISESGNRYTTSTTRSVITNKPNTHPTIAAVSRPTTRATTRSTNGPIRTTSQPGTYLNTPLSSRSPIRQSTIRSSTVFTTRSTTRPTIRSTTHAISRPTSSPTTRPTTRLTTRPTTRTTTRASVSPTTRPTVGLTTYQPTRTPTSITRRPIYTTQKQYTTTTRATTPYPTVSKPTTRPSTTTRPLTTTRYIPTTRQSVITQTTNRNSAIYLPRNNTISTNRSTTKSPYHYVSINKPTTRSTTSTRPSTTIRYSPTTRQPPTTRSTTRYSAITAFSTRQTSTTPRPYLFTSTTKKSVTTKDPFDHPFFQKFKAKFEKTTTTTNQKASTLAVNQNQTTISPYYAKYQENKVKTGAKTVLSYDFGQNRNTTSRPKSAFDVYLNWNKN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1ZBX6-1", "uniprot_id": "A1ZBX6_DROME", "id": "A1ZBX6-1", "name": "lysozyme", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MCLKARHPKTKR----------------------------DLMNMKTFCLWIVPVLILLQLGIEQVESKKYQRCELTRVLVEN--YNFDKTFISNWICLVEHESYLDTTKVTKKGNE-SKNYGLFQINSKDYCSEG-RKGGQCNMKCEDFSNDDISDDIACARMIQEREG------FKYWKGWDRFCRNP--QNLPNLRVACNLRSLSPVRSPRGFLTG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: : ** ::: * . * : .*:*:. .** ::. : : : ..****: . :* * :.* : : ::.. : * : * : . : * :. *: * . .: ", "identical_positions": 21, "similar_positions": 42, "identity": "1.54%" }, { "cls_id": "homologset.agr.RGD:1308402", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ER64-1", "uniprot_id": "OSBL5_MOUSE", "id": "Q9ER64-1", "name": "Oxysterol-binding protein-related protein 5", "aln": "------------------------------------------MKEEAFLRRRFSLCPPAS--------TPQKTDPRK---------------------------VPRNLLLGCENELGPITPGRDMESNGPSQPR------------------------------DEEPQTPGSATKVPLAEYRLCNGSD----KECTSPTTRVSKKDALKAQKENYRQEKKRATKQLFSALTDPSVVIMADSLKIRGTLKSWTKLWCVLKPGVLLIYKTPKVG--QWVGTVLLHCCELIERPSKKDGFCFKLFHPLDQSVWAVKGPKGESVGSITQPLPSSYLIFRAASESDGRCWLDALELALRCSSLLRLSTCKQGRDGEQGSSPDASPSSLYGLPTSATIP-DQDLFPLNGSALENDAFSDKSERENAEDSDAETQDHSRKTNESGSDLLDSPGGPWR-GTTYVEQVQEELGELDETSQVETVSEENKSLMWVLLRQLRPGMDLSRVVLPTFVLEPRSFLGKLSDYYYHGDLLSRAAAEDDPYCRMKLVLRWYLSGFYKKPKGIKKPYNPILGETFRCRWLHPQTNSHTFYIAEQVSHHPPVSAFYVSNRKDGFCMSGSITAKSKFYGNSLSALLDGKAKLTFLNRK------EEYTLTMPYAHCRGILYGTMTMELGGKVNIECEKNNLQAELDFKLKPFFGSSANINQISGKIMSGEEVLARLTGHWDRDVFIKEESSGGTELFWTPSEEVRRQRLKRHTVLLEEQSELESERLWQHVTRAIREGDQHKATQEKSVLEEAQRQRAREHQQSLTPWKPQLFLLDPLTQEWRYRYEDLSPWDPLKDIAQYEQDGILHTLQRETMSGQTTFLGSPDSRHKRPSSDRRLRKASDQPSGHSQVTESSGSTPESCPDLSDE----DFVPGGESPCPRCRREVHRLKMLQEAVLSIQEAQQELHRHLSTMLSSTVRAGQAPAPSLLQNP---------------RSWFLLCIFLTCQLFINYILK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZYG1-1", "uniprot_id": "A0A8I5ZYG1_RAT", "id": "A0A8I5ZYG1-1", "name": "Oxysterol-binding protein", "aln": "-------------MCREQRWALVCGQKRLELLAPQKPPSTHTMKEEAFLRRRFSLCPPAS--------TPQKTDPRK---------------------------LPRNLLLGCENELGPITPGRDMESNGPSQPR------------------------------DEEPLTPGSATKVPLAEYRLCNGSD----KECTSPTTRVSKKDTLKAQKENYRQEKKRATKQLFSALTDPSVVIMADSLKIRGTLKSWTKLWCVLKPGVLLIYKTPKVG--QWVGTVLLHCCELIERPSKKDGFCFKLFHPLDQSVWAVKGPKGETVGSITQPLPSSYLIFRAASESDGRCWLDALELALRCSSLLRLSTCKQGRDGEQGSSPDASPSSLYGLPTSATIP-DQDLFPLNGSALENDAFSDKSERENADDSDAETQDHSRKTNESGSDLLDSPGGPRR-GTTYVEQVQEELGELDETSQVETVSEENKSLMWVLLRQLRPGMDLSRVVLPTFVLEPRSFLSKLSDYYYHGDLLSRAAAEDDPYCRIKLVLRWYLSGFYKKPKGIKKPYNPILGETFRCCWLHPQTNSHTFYIAEQVSHHPPVSAFYVSNRKDGFCMSGSITAKSKFYGNSLSALLDGKAKLTFLNRK------EEYTLTMPYAHCRGLLYGTMTMELGGKVTIQCEKNNLQAELDFKLKPFFGSSTSINQISGKITSGEEVLARLTGHWDRDVFIKEEASGGTKLFWTPSEEVRRQRLKRHTVLLEEQSELESERLWQHVTRAIHEGDQHKATQEKSVLEEAQRQRAREHQQSLTPWKPQLFTLDPLTQEWRYQYEDYSPWDPLKDIAQYEQDGILHTLQRETMSGQTAFLGSPESRHKRPSSDRRLRKASDQPSGHSQVTESSGSTPESCPDLSDE----DFVPGNESPCPRCRREVHRLRMLQEAVLSIQEAQQELHRHLSAMLRSTVRAGQAPAPGLLQNP---------------RSWFLLCIFLTCQLFINYILK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H0X9-1", "uniprot_id": "OSBL5_HUMAN", "id": "Q9H0X9-1", "name": "Oxysterol-binding protein-related protein 5", "aln": "------------------------------------------MKEEAFLRRRFSLCPPSS--------TPQKVDPRK---------------------------LTRNLLLSGDNELYPLSPGKDMEPNGPSLPR------------------------------DEGPPTPSSATKVPPAEYRLCNGSD----KECVSPTARVTKKETLKAQKENYRQEKKRATRQLLSALTDPSVVIMADSLKIRGTLKSWTKLWCVLKPGVLLIYKTPKVG--QWVGTVLLHCCELIERPSKKDGFCFKLFHPLDQSVWAVKGPKGESVGSITQPLPSSYLIFRAASESDGRCWLDALELALRCSSLLRLGTCKPGRDGEPGTSPDASPSSLCGLPASATVHPDQDLFPLNGSSLENDAFSDKSERENPEESDTETQDHSRKT-ESGSDQSETPGAPVRRGTTYVEQVQEELGELGEASQVETVSEENKSLMWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRMKLVLRWYLSGFYKKPKGIKKPYNPILGETFRCCWFHPQTDSRTFYIAEQVSHHPPVSAFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRA------EDYTLTMPYAHCKGILYGTMTLELGGKVTIECAKNNFQAQLEFKLKPFFGGSTSINQISGKITSGEEVLASLSGHWDRDVFIKEEGSGSSALFWTPSGEVRRQRLRQHTVPLEEQTELESERLWQHVTRAISKGDQHRATQEKFALEEAQRQRARERQESLMPWKPQLFHLDPITQEWHYRYEDHSPWDPLKDIAQFEQDGILRTLQQEAVARQTTFLGSPGPRHERSGPDQRLRKASDQPSGHSQATESSGSTPESCPELSDEEQDGDFVPGGESPCPRCRKEARRLQALHEAILSIREAQQELHRHLSAMLSSTARAAQAPTPGLLQSP---------------RSWFLLCVFLACQLFINHILK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4JCZ0-1", "uniprot_id": "A0A0B4JCZ0_DROME", "id": "A0A0B4JCZ0-1", "name": "Oxysterol-binding protein", "aln": "MQQPATPSTPVNNAPSATPSAASGPAASAPAVASSTPIRINSAKQQGAAGGGDTLAHPATPHSHSMPGTPHQQPQSSSVPTGGHLLQLQAPLPSAGGGTGAGAVTPSGLSMGASNQSLGVSVGAASSVSGISITPPNSAGLRQSTVFDFKFKRRPSLKVLMTKLPSTDSLSNSPAPSSPGIANWASDNRDGNVADKSAADAAKLNRKESYKAQRKNYRREKKRVASELMNSLQDPAVIVLADWLKVRGTLKSWTKLWCVLKPGLLLIYKSQKTKSSHWVGTVMLTSCQVIERPSKKDGFCFKLFHPLEQSIWAPRGPDKETIGAVVQPLPTAYLIFRAPSQAAGKCWMDALELSLRCSALLLRSNSSTG------TAPTSSYIGEP-LPVSHETQWSEADYEKHFNDHDLDADS-QNEAPNAVMSGLESESESDPAEPAQDDVVD----QQCVETSYVPFTEEEFGEQGE--QVEELAEENKSLIWCIVKQVRPGMDLSKVVLPTFILEPRSFLDKLSDSYYHADLLSKAVQEDDAFTRMKLVVQWYLSSFYKKPKGLKKPYNPILGERFRCYWQHP-SGSRTFYIAEQVSHHPPVSAFYVTNREDGFSITCSILAKSKFYGNSTSAVLEGAATMTLLPRG------ECYTATTPYAHCKGILMGTLSMELGGKINIECENTGYRTELEFKLKPFLGGADATNVVVGKIKLGKETLATINGHWDKECRVKDSKTGEETVLFKVDAETRSKRLTRYMVPLDLQEANESQRLWQRVSEAIANEDQVAATEEKTVLEERQRADAKERLSSDSVHMPDLFELDSYG-QWLYKYADLRPWDSRNDVRQYECQ--FKVLTQTRHKSVPIVHGAEMIHPLRSSIETLSRTQRQSPAGQPLPPGGSAVPKAKNKSLVLAPRDTNSDSSQSPQGAVKRSSSSAIKQLALAVDQVNRVLEQHTRQLNEISQRLERMQYSPPPSSMSAHSLHMLGGGVSQSTVIKSLIYALIGLAFSLILRWLFK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q02201-1", "uniprot_id": "OSH6_YEAST", "id": "Q02201-1", "name": "Oxysterol-binding protein homolog 6", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGSKKLTVGSDSHRLSKSSFSSNKSSHS--------------------------------------------------------------------------ATKDQPIDTDDIDEDD----------------------------------------------ESGHNIILNIISQLRPGCDLTRITLPTFILEKKSMLERVTNQLQFPEFLLQAHSEKDPLKRFLYVMKWYLAGWHIAPKAVKKPLNPVLGEYFTAYWDLP-NKQQAYYISEQTSHHPPECAYFYMIPESSIRVDGVVIPKSRFLGNSSAAMMDGSTVLQFLDIKDGNGKPEKYVLTQPNVYVRGILFGKMRIELGDHMIIKSP--NFQADIEFKTKGYVFGTYDAIEGTVKDYDG-NAYYEISGKWNDVMYLKDLKQPRSSPKVFLDTHKESP-LRPKVRPLSEQGEYESRKLWKKVTDALAVRNHPVATEEKFQIEDHQRQLAKKRIEDGVEFHPKLFRRSKPGEDLDYCIYKNIPVDEDPEKQIRSILQIAPILPGQQFTDKFFIPAFEKIKSQKKMIENEKQNPAKQ-------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.. ::*: : *..: : . .*.: :. :. :.. *..:.:: :: *:*** **:::.****:** :*:* :::: . ::* :* *.*. *: *::***:.:: **.:*** **:*** * . * * . .:::**:**.***** .*:. :..: : : .**:* *** :*:::* : : :* * *. * * .: :*:* *.: :***.:: *:. . :::::** * :. .: * * :. :.*:*: :*: . . . * *. * **.:**::*: *: :: **:** :*: ** *::: .. *.** . : * . * * : . * . . : : : :. .. ", "identical_positions": 103, "similar_positions": 149, "identity": "10.16%" }, { "cls_id": "homologset.agr.RGD:1308403", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GHP9-1", "uniprot_id": "A0A8I6GHP9_RAT", "id": "A0A8I6GHP9-1", "name": "", "aln": "MLEGLVAWVLNTYLGKYVNNLNTDQLSVALLKGAVELENLPLKKDALKELELPFEVKAGLIGKVTLQIPFYRPHVDPWVISISGLHVIGAPEKIQDFNDEKEKLLERERKKVLLQALEERWKSERRQQKGESYWYSVT------ASVVTRIVENIELKIQDVHLRFEDGLTNPSHPFAFGICIKNVSMQNAANEPVQKLMRK-------KRLDVAEFSIYWDVNCTLLGDLPQA--ELQEAMARSMESRSHHYILEPVCASALLKRNCSKEPLRSRHSPRIECDIQLETIPLKLSQLQYRQIMAFLKELERKERQVKFRKWKPKVAVSKNCREWWYFALNANLYEIREQRKCCTWDFLLHRARDAVFYTDRYFNKLKGGVLSADDKEEMCRIEEEQSFEELKILRELVHDRFYKQEELAESLREP---QFD-SPGASP-GDPDGSGGSGMLQYLQSWFPGWGGWYG--QQSPEGKVAEGLTAESHEHWMPEDILGTEEFFDPTADASCMNTYTKRDHVFAKLNVQLQRGTVTLLHQERGAAHANESAFMQLEFSDVKLLAESLPRRNSSLLLVRLGGLFLRDLATEGTMFPLLVFPNPQKEVGRVSQSFGLQTASEDRSDQYSAADPDNPVFEMLYERNPVHSHFERRLHVSTRPLNIIYNPQAIKKVADFFYKGKVHTSGFGYQSELELRVAEAARRQYNKLKMQTKAEIRQTLDRLLVGDFIEESKRWTVRLDISAPQVIFPDDFTFKNPVLVVVDLGRMLLTNTQEDSRRKSGDDSASEENQFSDDEYKTPLATPPSTPPPET--NSSNGEKTPPFSGVEFSEEQLQAHLMSTQMYERYSLTFMDLQVMVGRVRDNWKRVQDIDVGPTHVVEKFNVHLQLERRLIYTSDPKYPGAVLSGNLPDLKIHINEDKISALKNCFALLTTPETKPSD------------TQFREKIFPQEGPRGSLQDSVMNLTQSIVMLEQHTREVLVESQLLLAEFKVNCMQLGVESSGRYISVLKVFGTNAHFVKRPYDAEVSLTVHGLLLVDTMQTYGADFDLLMASHKNLSFDIPTGSLRDSRAQSPVSG--PNVAFQTDVATLNDQ-SATTSVSLEKILTKEQESLIKLEYQFVSSECPSMNLDSTLQVISLQVNNLDIILNPETIVELIGFLQKSFPKEKDDVSPQPLMTDLERSIMEQGTVQSTYEQNTEVAVEIHRLNLLLLRTVG---MSDGERHGRKIATASIGGTKVNVSMGSSFDMNGSLGCLQLMDLTQENVKNQYVVSIGN-------SIGYENIVSDIG--YFESVFVRMEDASLTEALSFTFAEKSKQECFLNLKMASLHYNHSAKFLKELTLSMDELEENFRSMLKSAATKVTTVLATKTAEYSEMVSLFETP-----KKTRDPFVLEENEIYGFG----LPSPRSDTVKLILNINIESPVVSIPRRPGSPELLVGHLGQIFIQNFVAGDDESRSDRLQVEIKDIKLYSLNCTQLAGRDGAGPEVSRAFCPPSGSASVSSQEEAHFTRHDFFESLHRGQAFHILNNTTIQFKLEKIPIERETELTFSLSPDELGTSSIMKIEGKFVNPVQVVLAKHVYEQVLQTMDNLVYSEDLNKFAASAPPSPCPNS----PLPPLSSCGEPTAEKKENGLFSHSSFSSASQKSLSVK------ESKAFTQIQANFCISELQVQLSGDLTLGAQGLVSLKFQDFEVEFSKDHPQTLSIQIALRSLLMEDLLEKNPDSKYKSLMVSRGAPKPSSLAQKEYLSQSCPSVSCVEYPAMPRSLPSHMEEAPNVFQLYQR-PISTCRKKQKEVQDKSYPQTPPPSPSVDEPKVLVGKSKFDDSLVHINIFLVDKKHPEFSSSYGRINRSIDVDFNCLDVLITLQTWVVILDFFGIGSTADNHAMKVPP-------EGPLQNVKAEATASMQSELQEPVNSKLDLKVHSLSLVLSKATSELAKANVSKLVAHMEMIEGDLALQGSIGSLSLSDLTPHGDLYRERFTTSGEEALIFQ-TFKYGQPDPLLQREHDIRVSLQMASVQYVHTQRFQAEVVAFIQHFTQLQDVLGRQRAAVEGQTVRDQAQRCSRILLDIEAGAPVLLIPESSRSNNLIVANLGKLKVKNKFLFAGFPGTFSLQDKESVPSASPTDTMKHSMKKMPSTEDPKGPQVQGLFMMPPAGMGLGSLKSDFVPSASIKQRGQQAVPPISQSSSSP--EDHVCLLDCIVVDLQDMDIFAAERHPRE-GSKASESSSGDLIFPSYFVRQTGGSLLTEPCRLKLQVERNLDKEISHTVADISVHGSLSSVHCSLDLCKYKLIRGLLENNLGEPIEDFMRPYDLQ-----------DPRIHTVLSGEVYTCMCFLIDMVNVSLELKD-PKGKEGTGSLARFDFKKCKLLYESFSNQTKSINLVSHSMMAFDTRYSGQ-KPSHGMTNVFNCIFQPSKSSSATQGSIQIELHFRSTKDSSCFTVVLNNLRVFLIFDWLLLVHDFLHTPSDVKKQN-VTPARYRNASSES----AVVPKTVKSGVVTKRSSLPVSNERHLEVKVNVTGTEFVVVEDVSCFDTNAIILKGTTVLTYKPRFVDRPFSGSLFGIEVFSCRLGNEQDTALSIVDPVQIQVELVGNSSYQNSSGLMDAFNSEDFPPILEIQLQALDIRLSYNDVQLFLAIAKSIPEQASAAAPDSAALEADSVSSNLPGASRIGEDVREGSRHTLDPVLELQLARLQELGFSMDDCRKALLVCQGQLKKAASWLFKNAEPLKSLSLVSSS-RDNQGAMSAPRISGVEVKAESVCICFIDDCMDCDVPLAELTFSRLNFLQHIRTNPE------------GYAHFTLSGDYYNRALSGWEPFIEPWPCSVSWQQQAASRLHPPRLKLEAKAKRRLDINITSVLIDQYVSTKESWLADYCKEDKE-TESAKTEDWMGSSVDPPCFGQSLPLVYLRTRSTASLTNLEHQIYARAEVKTPKRRQPFVPFALRNHTGCTLWFATLTTTPTRAALSHSGSPGVVPEGNGAFLDDTHNVSEWREVLTGEEIPFEFEARGKLRHRHTHDLRIHQLQVRVNGWEQVSPVSVDKVGTFFRYAAPDKNSSSSTIGSPSSRTNIIHPQVYFSSLPPVRVVFAVTMEGSARKVITVRSALIVKNRLETPMELRLDSP-SAPDKPVVLPAIMPGDSFAVPLHLTSWRLQARPKGLGVFFCKAPIHWTNVVKTAEVSSSKRECHSMDTEK--SRFFRFCVAIKKENYPDYMPSNIFSDS-AKQIFRQPGHTIYLLPTVVICNLLPCELDFYVKGMPINGTLKPGKEAALPTADTSQNIELGVSLENFPLCKELLIPPGTQNYMVR-MRLYDISRRQLNLTIRIACRAEGSLKIFISAPYWLINKTGLPLIFRQDNAKTDAAGQFEEHELARSLSPLLFCYADKEQPNLCTMRIGRGIHPEGMPGWCQGFSLDGGSGVRALKVIQQGNRPGLIYNIGIDVKKGRGRYIDTCMVIFAPRYLLDNKSSHKLAFAQREFARGQGTANPSGYISTLPGSSVVFHWPRNDYDQLLCVRLMDVPNCIWSGGFEVNKNNSFHINMRDTLGKCFFLRVEITLRGATYRISFSDTDQLPPPFRIDNFSKVPIVFTQHGVAEPRLRTEVKPMMSLHYAWDEPTLPPFITLTVKGAGSSEINCNMNDFQNNRQLYYENFIYIAATYTFSGLQEGKGRPVASHKAITCAELVLDVSPKTQRVILKKKEPGKRSQLWRMTGTGMLAHEGSAVPHNPNKPSATRSIEGSAILDIAGLAAVTDNRYEPLMLRKPDRRRSTTQTWCFHEGKLTCGLHGLVVQAKGGLSGLFDGAEVVLG-PDSSVELLGSVPPEQQFANQKMRPGSGMLSVRVIPDGPTRALQITDFCQRKS---ERSSYEVEELPVTEQELQKLRNPDTHQELEVLVRLEGGIGVSLIN-KVPEELVFASLTGINIHYTQLATSHMLELSIQDVQVDNQLIGTTQPFMLYVTPLSNENEVIETGPAVQVNAVKFPSKSALTNIYKHLMVTAQKFTVQIEEKLLLKLLSFFGYDQAESEVEKYDENIHEKTAE-QGGTPTRYYFENLKISIPQIKLSVFTSNKLPLDLKALKSTLGFPLIRFEDAVINLDPFTRVHPYETKEFIINDILKHFQEELLSQAARILGSVDFLGNPMGLLNDVSEGVTGLIKYGNVGGLIRNVTHGVSNSAAKFAGTLSDGLGKTMDNRHQ--SEREYIRYHAATSGEHLVAGIHGLAHGIIGGLTSVITSTVEGVKTEGGVSGFISGLGKGLVGTVTKPVAGALDFASETAQAVRDTATLSGPRTQAQRVRKPRCCT-GPQGLLPRYSESQAEGQEQLFKLTDNIQDEFFIAVEN-----IDSYCVLISSKAVYFLKSGDYIDREAIFLEVKYDDLYHCLVSKDHGKVYVQVTKKAANSSSGVSIPGPSHQKPMVHVKSEVLAVKLSQEINYAKSLYYEQQLMLRLSEDQEQLELDS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B1ART1-1", "uniprot_id": "B1ART1_MOUSE", "id": "B1ART1-1", "name": "", "aln": "MLEGLVAWVLNTYLGKYVNNLNTDQLSVALLKGAVELENLPLKKDALKELELPFEVKAGLIGKVTLQIPFYRPHVDPWVISISGLHVIGGPEKIQDFNDEKEKLLERERKKALLQALEERWK------KGEPYWYSVT------ASVVTRIVENIELKIQDVHLRFEDGVTNPSRPFAFGICIKNVSMQNAANEPVQKLMRK-------KRLDVAEFSIYWDVNCTLLGDLPQA--ELQEAMARSMESRSHHYILEPVCASALLKRNCSKEPLRSRHSPRIECDIQLETIPLKLSQLQYRQIMAFLKELERKERQLKFRKWKPKVAVSKNCREWWYFALNANLYEIREQRKCWTWDFLLHRARDAVFYTDRYFNKLKGGVLSADDKEEMCRIEEEQSFEELKILRELVHDRFYKQEELAESLREP---QFD-SPGTSP-GDPDGSGGSGMLQYLQSWFPGWGGWYG--QQSPEGKVVEGLTAESHEHWTPEEILGTEEFFDPTADASCMNTYTKRDHVFAKLNVQLQRGTVTLLHKEQGTAHANESAFMQLEFSDVKLLAESLPRRNSSLLLVRLGGLFLRDLATEGTMFPLLVFPNPQKEVGRVSQSFGLQTASEDRSDQYSAADPDNPVFEMLYERNPVHSHFERRLHVSTRPLNIIYNPQAIKKVADFFYKGKVHTSGFGYQSELELRVAEAARRQYDKLKVQTKAEIRQTLDRLLVGDFIEESKRWTVRLDISAPQVIFPDDFTFKNPVLVVVDLGRMLLTNTQEDSRRKSGDGSASEENQFSDDEYKTPLATPPSTPPPET--SSSNGEKTPPFSGVEFSEEQLQAHLMSTQMYERYSLTFMDLQVMVGRVRDNWKRVQDIDVGPTHVVEKFNVHLQLERRLIYTSDPKYPGAVLSGNLPDLKIHINEDKISALKNCFALLTTPETKPSD------------TQIREKIFPQEGPRGSLQDSVMNLTQSIVMLEQHTREVLVESQLLLAEFKVNCMQLGVESSGRYISVLKVFGTNAHFVKRPYDAEVSLTVHGLLLVDTMQTYGADFDLLMASHKNLSFDIPTGSLRDSRAQSPVSG--PNVAFQTDVTTLNDQ-SATS-VSLEKILTKEQESLIKLEYQFVSSECPSMNLDSTLQVISLQVNNLDIILNPETIVELIGFLQKSFPKEKDDVSPQPLMTDLERSIVEQGTIQSTYEQNTEVAVEIHRLNLLLLRTVG---MADGERHGRKIATASIGGTKVNVSMGSSFDMNGSLGCLQLMDLTQENVKSQYVVSIGN-------SVGYENIVSDIG--YFESVFVRMEDAALTEALSFTFAEKSKQECFLNLKMASLHYNHSAKFLKELTLSMDELEENFRSMLKSAATKVTTVLATKTAEYSEMVSLFETP-----KKTREPFVLEENEIYGFG----LPSPRSDTVKLILNINIESPVVSIPRRPGSPELLVGHLGQIFIQNFVAGDDDSRSDRLQVEIKDIKLYSLNCTQLAGRDNAGPEVNRTFCPPSGLASVNSQEEAHFTRHDFFESLHRGQAFHILNNTTIQFKLEKIPIERESELTFSLSPDELGTSSIMKIEGKFVNPVQVVLAKHVYEQVLQTMDNLVYSEDLNKFAASAPTSPCPNS----PLPQLSSCGEPCVEKKENGLFSHSSFSSTSQKSLSVK------EAKAFTQIQANFCISELQVQLSGDLTLGAQGLVSLKFQDFEVEFSKDHPQTLSIQIALRSLLMEDLLEKNPDSKYKSLMVSRGAPKPSSLAQKEYLSQSCPSVSSVEYPDMPRSLPSHMEEAPNVFQLYQR-PISTCRKKPKEAQDKSYPQTPPPSPSVDEPNMLVGKSKFDDSLVHINIFLVDKKHPEFSSSYGRINRSIDVDFNCLDVLITLQTWVVILDFFGIGSTADNHAMKVPP-------EGLLQNVKAESSASMESEHQEPVNSKLDLKVHSLSLVLSKATSELAKANVSKLMAHMEMIEGDLALQGSIGSLSLSDLTPHGDFYRERFTTSGEEALIFQ-TFKYGQPDPLLQREHDIRVSLQMASVQYVHTQRFQAEVVAFIQHFTQLQDILGRQRAAIEGQTVRDQAQRCSRILLDIEAGAPVLLIPESSRSNNLIVANLGKLKVKNKFLFAGFPGTFSLQDKESVPSASPAGTPKHSMRKMTTTEDPKGPQVQGLFMMPPAGVGLGSLKSDFVPSASIKQRGQQAVPPVSQSSSSP--EDHVCLLDCIVVDLQDMDIFAAERHPRE-GSKASEHSSGDLIFPSYFVRQTGGSLLTEPCRLKLQVERNLDKEISHTVADISVHGSLSSVHCSLDLCKYKLIRGLLENNLGEPIEDFMRPYDLQ-----------DPRIHTVLSGEVYTCMCFLIDMVNVSLELKD-PKGKEGTGSLARFDFKKCKLLYESFSNQTKSINLVSHSMMAFDTRYSGQ-KPSHGMTNVFNCIFQPSKSSSATQGSIQIELHFRSTKDSSCFTVVLNNLRVFLIFDWLLLVHDFLHTPSDIKKQN-VTPARHRNASSES----AVVPKTVKSGVVTKRSSLPVSNERHLEVKVNVTGTEFVVVEDVSCFDTNAIILKGTTVLTYKPRFVDRPFSGSLFGIEVFSCRLGNEQDTALSIVDPVQIQVELVGNSSYQNSSGLMDAFNSEDFPPILEIQLQALDIRLSYNDVQLFLAIAKSIPEQASAAAPDSSALEVDSISCSLPGASRIGEDVREGSRHTLDPVLELQLARLQELGFSMDDCRKALLVCQGQLKKAASWLFKNAEPLKSLSLVSSSSRDNPGTMPAPRISGVEVKAESVCICFIDDCMDCDVPLAELTFSRLNFLQHIRTNPE------------GFAHFTLSGDYYNRALSGWEPFIEPWPCSVSWQQQASSRLHPPRLKLEAKAKRRLDINITSVLIDQYISTKESWLADYCKEDKE-TESAKTEDWMGSSVDPPCFGQ-------------------------TEVKTPKRRQPFVPFALRNHTGCTLWFATLTTTPTRAALSHSGSPGVVPEGNGAFLDDAHNVSEWREVLTGEEIPFEFEARGKLRHRHTHDLRIHQLQVRVNGWEQVSPVSVDKVGTFFRYAAPDKNSSSSTIGSPSSRTNIIHPQVYFSSLPPVRVVFAVTMEGSARKVITVRSALIVKNRLETPMELRLDSP-SAPDKPVVLPAIMPGDSFAVPLHLTSWRLQARPKGMGVFFCKVPIHWTNVVKTAEVSSSKRECHSMDTEK--SRFFRFCVAIKKENYPDYMPSNIFSDS-AKQIFRQPGHTIYLLPTVVICNLLPCELDFYVKGMPINGTLKPGKEAALPTADTSQNIELGVSLENFPLCKELLIPPGTQNYMVR-MRLYDVNRRQLNLTIRIACRAEGSLKIFISAPYWLINKTGLPLIFRQDNAKTDAAGQFEEHELARSLSPLLFCYADKEQPNLCTMRIGRGIHPEGMPGWCQGFSLDGGSGVRALKVIQQGNRPGLIYNIGIDVKKGRGRYIDTCMVIFAPRYLLDNKSSHKLAFAQREFARGQGTANPNGYISTLPGSSVVFHWPRNDYDQLLCVRLMDVPNCIWSGGFEVNKNNSFHINMRDTLGKCFFLRVEITLRGATYRISFSDTDQLPPPFRIDNFSKVPVVFTQHGVAEPRLRTEVKPMMSLDYAWDEPTLPPFITLTVKGAGSSEINCNMNDFQNNRQLYYENFIYIAATYTFSGLQEGKGRPVASHKAITCAELVLDVSPKTQRVILKKKEPGKRSQLWRMTGTGMLAHEGSAVPHNPNKPSATRSIEGSAILDIAGLAAVTDNRYEPLMLRKPDRRRSTTQTWSFHEGKLTCGLHGLVVQAKGGLSGLFDGAEVVLG-PDSSMELLGPVPPEQQFANQKMRPGSGMLSIRVIPDGPTRALQITDFCQRKS---ERSSYEVEELPVTEQELQKLRNPDTHQELEVLVRLEGGVGVSLIN-KVPEELVFASLTGINIHYTQLAASHMLELSIQDVQVDNQLIGTTQPFMLYVTPLSNENEVIETGPAVQVNAVKFPSKSALTNIYKHLMVTAQRFTVQIEEKLLLKLLSFFGYDQAESEVEKYDENIHEKTAE-QGGTPTRYYFENLKISIPQIKLSVFTSNKLPLDLKALKSTLGFPLIRFEDAVINLDPFTRVHPYETKEFIINDILKHFQEELLSQAARILGSVDFLGNPMGLLNDVSEGVTGLIKYGNVGGLIRNVTHGVSNSAAKFAGTLSDGLGKTMDNRHQ--SEREYIRYHAATSGEHLVAGIHGLAHGIIGGLTSVITSTVEGVKTEGGVSGFISGLGKGLVGTVTKPVAGALDFASETAQAVRDTATLSGPRTQAQRVRKPRCCT-GPQGLLPRYSESQAEGQEQLFKLTDNIQDEFFIAVEN-----IDSYCVLISSKAVYFLKSGDYVDREAIFLEVKYDDLYHCLVSKDHGKVYVQVTKKAANSSSGVSIPGPSHQKPMVHVKSEVLAVKLSQEINYAKSLYYEQQLMLRLSENQEQLELDS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5THJ4-1", "uniprot_id": "VP13D_HUMAN", "id": "Q5THJ4-1", "name": "Intermembrane lipid transfer protein VPS13D", "aln": "MLEGLVAWVLNTYLGKYVNNLNTDQLSVALLKGAVELENLPLKKDALKELELPFEVKAGFIGKVTLQIPFYRPHVDPWVISISSLHLIGAPEKIQDFNDEKEKLLERERKKALLQALEEKWKNDR-QQKGESYWYSVT------ASVVTRIVENIELKIQDVHLRFEDGVTNPSHPFAFGICIKNVSMQNAVNEPVQKLMRK-------KQLDVAEFSIYWDVDCTLLGDLPQM--ELQEAMARSMESRSHHYVLEPVFASALLKRNCSKKPLRSRHSPRIDCDIQLETIPLKLSQLQYRQIMEFLKELERKERQVKFRRWKPKVAISKNCREWWYFALNANLYEIREQRKRCTWDFMLHRARDAVSYTDKYFNKLKGGLLSTDDKEEMCRIEEEQSFEELKILRELVHDRFHKQEELAESLREP---QFD-SPGACP-GAPEPGGGSGMLQYLQSWFPGWGGWYG--QQTPEGNVVEGLSAEQQEQWIPEEILGTEEFFDPTADASCMNTYTKRDHVFAKLNLQLQRGTVTLLHKEQGTPQMNESAFMQLEFSDVKLLAESLPRRNSSLLSVRLGGLFLRDLATEGTMFPLLVFPNPQKEVGRVSQSFGLQTTSADRSDHYPAADPDGPVFEMLYERNPAHSHFERRLNVSTRPLNIIYNPQAIKKVADFFYKGKVHTSGFGYQSELELRVAEAARRQYNKLKMQTKAEIRQTLDRLLVGDFIEESKRWTVRLDISAPQVIFPDDFKFKNPVLVVVDLGRMLLTNTQDNSRRKSRDGSASEETQFSDDEYKTPLATPPNTPPPES--SSSNGEKTPPFSGVEFSEEQLQAHLMSTKMYERYSLSFMDLQIMVGRVKDNWKHVQDIDVGPTHVVEKFNVHLQLERRLIYTSDPKYPGAVLSGNLPDLKIHINEDKISALKNCFALLTTPEMKTSD------------TQIKEKIFPQEEQRGSLQDSVMNLTQSIVLLEQHTREVLVESQLLLAEFKVNCMQLGVESNGRYISVLKVFGTNAHFVKRPYDAEVSLTVHGLLLVDTMQTYGADFDLLMASHKNLSFDIPTGSLRDSRAQSPVSG--PNVAHLTDGATLNDR-SATS-VSLDKILTKEQESLIKLEYQFVSSECPSMNLDSTLQVISLQVNNLDIILNPETIVELIGFLQKSFPKEKDDLSPQPLMTDFERSFREQGTYQSTYEQNTEVAVEIHRLNLLLLRTVG---MANREKYGRKIATASIGGTKVNVSMGSTFDMNGSLGCLQLMDLTQDNVKNQYVVSIGN-------SVGYENIISDIG--YFESVFVRMEDAALTEALSFTFVERSKQECFLNLKMASLHYNHSAKFLKELTLSMDELEENFRGMLKSAATKVTTVLATKTAEYSEMVSLFETP-----RKTREPFILEENEIYGFD----LASSHLDTVKLILNINIESPVVSIPRKPGSPELLVGHLGQIFIQNFVAGDDESRSDRLQVEIKDIKLYSLNCTQLAGREAVGSEGSRMFCPPSGSGSANSQEEAHFTRHDFFESLHRGQAFHILNNTTIQFKLEKIPIERESELTFSLSPDDLGTSSIMKIEGKFVNPVQVVLAKHVYEQVLQTLDNLVYSEDLNKYPASATSSPCPDS----PLPPLSTCGESSVERKENGLFSHSSLSNTSQKSLSVK------EVKSFTQIQATFCISELQVQLSGDLTLGAQGLVSLKFQDFEVEFSKDHPQTLSIQIALHSLLMEDLLEKNPDSKYKNLMVSRGAPKPSSLAQKEYLSQSCPSVSNVEYPDMPRSLPSHMEEAPNVFQLYQR-PTSASRKKQKEVQDKDYPLTPPPSPTVDEPKILVGKSKFDDSLVHINIFLVDKKHPEFSSSYNRVNRSIDVDFNCLDVLITLQTWVVILDFFGIGSTADNHAMRLPP-------EGILHNVKLEPHASMESGLQDPVNTKLDLKVHSLSLVLNKTTSELAKANVSKLVAHLEMIEGDLALQGSIGSLSLSDLTCHGEFYRERFTTSGEEALIFQ-TFKYGRPDPLLRREHDIRVSLRMASVQYVHTQRFQAEVVAFIQHFTQLQDVLGRQRAAIEGQTVRDQAQRCSRVLLDIEAGAPVLLIPESSRSNNLIVANLGKLKVKNKFLFAGFPGTFSLQDKESVPSASPTGIPKHSLRKTTSTEEPRGTHSQGQFTMPLAGMSLGSLKSEFVPSTSTKQQGPQPTLSVGQESSSP--EDHVCLLDCVVVDLQDMDIFAAERHPRE-YSKAPEDSSGDLIFPSYFVRQTGGSLLTEPCRLKLQVERNLDKEISHTVPDISIHGNLSSVHCSLDLYKYKLIRGLLENNLGEPIEEFMRPYDLQ-----------DPRIHTVLSGEVYTCMCFLIDMVNVSLELKD-PKRKEGAGSLARFDFKKCKLLYESFSNQTKSINLVSHSMMAFDTRYAGQ-KTSPGMTNVFSCIFQPAKNSSTTQGSIQIELHFRSTKDSSCFTVVLNNLRVFLIFDWLLLVHDFLHTPSDIKKQNHVTPSRHRNSSSES----AIVPKTVKSGVVTKRSSLPVSNERHLEVKVNVTGTEFVVIEDVSCFDTNAIILKGTTVLTYKPRFVDRPFSGSLFGIEVFSCRLGNEHDTALSIVDPVQIQMELVGNSSYQNSSGLMDAFNSEDFPPVLEIQLQALDIRLSYNDVQLFLAIAKSIPEQANAAVPDSVALESDSVGTYLPGASRVGEEIREGTRHTLDPVLELQLARLQELGFSMDDCRKALLACQGQLKKAASWLFKNAEPLKSLSLASTS-RDSPGAVAAPLISGVEIKAESVCICFIDDCMDCDVPLAELTFSRLNFLQRVRTSPE------------GYAHFTLSGDYYNRALSGWEPFIEPWPCSVSWQQQAASRLHPPRLKLEAKAKPRLDINITSVLIDQYVSTKESWMADYCKDDKD-IESAKSEDWMGSSVDPPCFGQSLPLVYLRTRSTASLTNLEHQIYARAEVKTPKRRQPFVPFALRNHTGCTLWFATLTTTPTRAALSHSGSPGVVPEGNGTFLDDTHNVSEWREVLTGEEIPFEFEARGKLRHRHTHDLRIHQLQVRVNGWEQVSPVSVDKVGTFFRYAAPDKNSSSSTIGSPSSRTNIIHPQVYFSSLPPVRVVFAVTMEGSARKVITVRSALIVRNRLETPMELRLDSP-SAPDKPVVLPAIMPGDSFAVPLHLTSWRLQARPKGLGVFFCKAPIHWTNVVKTAEISSSKRECHSMDTEK--SRFFRFCVAIKKENYPDYMPSNIFSDS-AKQIFRQPGHTIYLLPTVVICNLLPCELDFYVKGMPINGTLKPGKEAALHTADTSQNIELGVSLENFPLCKELLIPPGTQNYMVR-MRLYDVNRRQLNLTIRIVCRAEGSLKIFISAPYWLINKTGLPLIFRQDNAKTDAAGQFEEHELARSLSPLLFCYADKEQPNLCTMRIGRGIHPEGMPGWCQGFSLDGGSGVRALKVIQQGNRPGLIYNIGIDVKKGRGRYIDTCMVIFAPRYLLDNKSSHKLAFAQREFARGQGTANPEGYISTLPGSSVVFHWPRNDYDQLLCVRLMDVPNCIWSGGFEVNKNNSFHINMRDTLGKCFFLRVEITLRGATYRISFSDTDQLPPPFRIDNFSKVPVVFTQHGVAEPRLRTEVKPMTSLDYAWDEPTLPPFITLTVKGAGSSEINCNMNDFQDNRQLYYENFIYIAATYTFSGLQEGTGRPVASNKAITCAELVLDVSPKTQRVILKKKEPGKRSQLWRMTGTGMLAHEGSSVPHNPNKPSAARSTEGSAILDIAGLAAVTDNRYEPLMLRKPDRRRSTTQTWSFREGKLTCGLHGLVVQAKGGLSGLFDGAEVVLG-PDTSMELLGPVPPEQQFINQKMRPGSGMLSIRVIPDGPTRALQITDFCHRKS---SRS-YEVDELPVTEQELQKLKNPDTEQELEVLVRLEGGIGLSLIN-KVPEELVFASLTGINVHYTQLATSHMLELSIQDVQVDNQLIGTTQPFMLYVTPLSNENEVIETGPAVQVNAVKFPSKSALTNIYKHLMITAQRFTVQIEEKLLLKLLSFFGYDQAESEVEKYDENLHEKTAE-QGGTPIRYYFENLKISIPQIKLSVFTSNKLPLDLKALKSTLGFPLIRFEDAVINLDPFTRVHPYETKEFIINDILKHFQEELLSQAARILGSVDFLGNPMGLLNDVSEGVTGLIKYGNVGGLIRNVTHGVSNSAAKFAGTLSDGLGKTMDNRHQ--SEREYIRYHAATSGEHLVAGIHGLAHGIIGGLTSVITSTVEGVKTEGGVSGFISGLGKGLVGTVTKPVAGALDFASETAQAVRDTATLSGPRTQAQRVRKPRCCT-GPQGLLPRYSESQAEGQEQLFKLTDNIQDEFFIAVEN-----IDSYCVLISSKAVYFLKSGDYVDREAIFLEVKYDDLYHCLVSKDHGKVYVQVTKKAVSTSSGVSIPGPSHQKPMVHVKSEVLAVKLSQEINYAKSLYYEQQLMLRLSENREQLELDS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TJB7-1", "uniprot_id": "A0AB32TJB7_DANRE", "id": "A0AB32TJB7-1", "name": "", "aln": "MLEGLVAWVLNTYLGKYVSNLNTDQLSIALLKGAVELENLPLRKDALRGFDLPFEVKAGVIGKITLQIPFYRPHSDPWVICMSQLNLIIGPALPQEYDEVQEREAEREQKKQLLKALEDKWKSEC-EQKGESYWYSVT------ASVVTRIVENIELKIQGVHLRFEDDFSNPEKPYAFGVCIKNVSAQNCSKEPAQKLIRQ-------KELEISEFSVYWDTECTMLGDLPSS--EIQERMSKCMQSREHQYIFEPVCASVLVRRNASKEPLRSRNTPRIEGQVQLEPLSLRLSQVQYQQIMAFLKELDRREKEMLFRKWRPKLTISGNCRQWWMFAINANLHEIRKQRRHGSWDFALHRARDAKLYTSLYVQRLKGVTLSPQEESEMERIEDEQTLEELQILRETVYVSFRKHEEIAESLREP---LINESPATSPSGSIPKSGSSGMIQYLQSWFPGWGGWYGGTERGPDGQPVSDELLPGTAQW--EILAETDDLFDPLEDSQTLNTFTRRDHLFARLDFKLEKAAVTLYHENKNKPLLSESGVIQLEFSGVKIEVESLPRSESSLLTVKLGGLFLRDLTTQGSIFPVLVSPKPDKVVVAINQPFGQTNSTEYSNPASDVESSAPPVFEMIYERNPIRSKFERRLEVNTSPLNIIYNPQAIKKVAEFFYKGRVHTSGFGYQSELELRVAEAARRQYNKLKMQTKAEIRQTIDQLLVGEFIENSKHWTMKLDICAPQVIFPDDFQSEDPMLVVVDLGRILLTNSQEDHKTNLKTSQTEGE---SDEEFQTPLATPPASPPPEQEVDVKGQEKPRDFSSVKSSE---GAQIISRNLYEKYSLSFNDLQIMVGHYKDNWKHLQESDVGPTHVVEKFNVLLQLEQRLRYTSDPQFPGAVLSGTLPDLKVHINLEKMTALRSCLARLGNSGADEGDNNGENLKSPDPLTLRHEKIFQREDSDWKLQGSDKNLTKSVMTLEQHTREVLVESKLLLVEFNINYMQLGIESGGRYISVLKVFGTNAHFVKRPYDAMVSLTVHGLYLVDTLQTYGSDFDLLVASHKHLSFDVPTGSLRESQPTSPVSP--DNKSPELPGLHRNSSDLAFDKASPRGSPLRDQEALIKLEYQFISSDCPSMNLDSSLQVTSMQVNNLDIILNPETMVELLKFLQQSFPKEES--SPTQQIAPLPNGEENEENYQSTYVQNKELTVEIHRLNLLLLRTVTTGTVLGGEKKGMKIATASINGTKVNVSMGSRLDVNGSLGCIQLVDLTQEGGRSQFVVSIG--------SAEDSTATDGVA--FFP-----IAGMTPSEALSFRFMEKSQGECSLQLQMASLHYNHSAKFLKELSLSANEVEDNFRFMLKTAATKVSTVLVTKTAEYSGMVSLFDNPSRRSRRQSQCNWTLDPFEEDDFCDPEKEPALDSFLVKLTLDVSIESPVVSIPRKPGHPELLVGHLGSIQIQNFVTGQDSER-EKLQVEVKDIRLYSVNTSNLFLKKGARLNSSTTSGPSPSHGGNISLNEPQFTRHDFFEYISRGKAFHILKDATIQLTVEKVPVDENSTFTFLSCDEPYQSTGILRVEGKFVNAVQVCLCKPVYEQVLQTLDNLSFTEDQRVTPSQPPTPPPPTPSSTKPHRFPDHQGGLFARDPPHGGVSYSTLSSSLSATLPLHNESPPLQPPSFTQVRATFRVSELQVQLSGDLSQGSQGLVSLRFQDLEGDFTKDHPHSISIQLALHSLLMEDLLEPNPESKYKHLMVSRGAPKPSTFSPKEYLSQSCPTASNVLYTEMPRSLPAQFEEAQNVFQFYQRHPSTPSASSRKSKKDAECPSTPPPSPSRQTPSPHP-RPDFDDSLVHINVLMVDRRHPEFKTRYGSIGRSVDVDFNCLDILITLQTWVMILDFFGIGSTANNHAVKVPTTTLQPMHEHSPENSTLNDLSDLYPEIEEGVNTKLDLKVHSLSLVLRKKTNELAKASVSKLFTHMEMIDGDLALQGSLGSLSLSDLTPHGDLYRERFTTRGGEALVYN-IYKYGETDFFLQREYDMKVSLQMASVQYVHTQRFQAEVVAFIQHFTQLQDVLGRQRAAVEGQAVRERPQRAARVLLDIEAGAPVLLIPESSRSKRLIVANLGQLRVRNCFLPAGARGTFSLRDKVEKLTMAHTFFPSLDRVKDVHFTSDAGKTSQ-------------KRPTSFSTSSGFMLGKPQPSLGCIPEGDVLGLEDHVCLLDCIALDLQEMDIFAAERLPCEPWDSAGKHLETDLVFPSYSVRRSGESLLKERCHLKLKVERNLDKELSHAVPDMSIHGSLSSVHCSLDLKRYQMIRGLLEHNLGEPVEEFLRPYNLQ-----------DPSSYTVLSGDVFTSLSLLVDMKDVSLELLDNHKSTGHNCSLARFDFMKSKLLFESFSNGSKSVNLVSHSLLAHDTRLTGSSAPTEGKHNVFDCILQPSRTG-TNRASLQLELHYRSTRDSSCFTVVLNNLRVFLIFDWLQLVQDFLHMP--VEKGTAPTHQRWPSGSSDQGCTGAVMPKTVKSGVVTKRSTVPVTQDKQLEVKINVTGTEFVVVEDSSCLDTNAIILKGTTVLTYKPRLLDRPFSGSLAGIEVFSCRLGSEQETALSIIDPVNVQMELCGSPTYQSSSGLLDAFNIEDFPPLLEIQFPALDIRLSYNDVQLFLAIAKSIPTAASANPSDT---AVDAESSASTASTDTPSKTKDSFRQKTEALLEGQLTRLQDLGFRKEDCRRALIHCRGQLDQAATWLWENAESMSGRSRTNSG----SSSHSAPPLSGVEVKAENVCICFIDDCLDCDVPLAEITFSRLYVLQRIGSMQE------------GKASFTLSGDYYNRELSGWEPFIEPWPCFLDWQRQAAGRLHPPRLKIGVRAKQRLDVNITSVLLEQYSTTKTSWLADYCKEDEQSPQPSAALSWMGSSVDPPSFGQSLPLAYLRTRSSTSLTCLEQQIHARADMKLSKRRQPFVPYALRNHTGCTMWFATLTTTPTRVALSHSSSADSISEVHGPGTDDTHNISQWREVLPGEEIPFEFEAREKLRHRHTHELKLHQLLVRVVGWEQVKPVSVDKVGVFFRYAAPDRNNPSSTVGSPISRTNIIHPHVYFSALPPVRVVFSITMEGSARKVITVQSALTVKNRLEVPMEVRLDSP-SAPDKPVVLPPILPGEALAIPLHLTSWRLQARPKGLGLFFCKVPIHWTSVERPGEVSSSKRECQSADFDEQLKRSFRFCVVIKKENYPEQQPAKTVAGGGTKQIYRQPGHTIFLLPTLVLANLLPCDLNYYIKGTSIKGTMKPGKEAVLHAADTSQNIEIGVLLENFPVCKELLIPPGTQNYVVR-MRLYDVNKRLLCLTIRIILRAQGALKILISAPYWLANKTGLPLIFRQDNGKTDAAGQFEEHELARSLSPLLFCYTDKEQPNMCTMRIGKGIHPDGVPGWCQGFSLDGGSGVRAVKVIQHGNRPGLIYNIGINVRKGKGRYRDTHIVTFAPRYLLDNRSSHKLAFSQREFARGKGTANPEGYISTLPGSSVVFHWPRNDYDQLLCVRLMDVPNCTWSGGFEVNKPKSFHINMRDTLGNCFFLRAEIALKGATHQISFSDTDQLPPPFRIDNISEVPIQFWQHGVADIRLHTEVKPGADLDYACDEPILEPYLTVTVKGAGSSEVTADMNFFREYNKLYYENFIYIAASFTFS--EDGGKRPVGKNRAVSCAELVLDVETKTQRVILKKKEPGKRSQLWRMTGSGMLCHEGSSPPQ--SKPSQPRPLSSSLVLDIAGLAAVTDNSYEPLMLRRPDSRRSTTQTWHFNSGMLTCGLPRLVVQVSGGVSGLYDGAEVVLG-PDS---GILEATPEQQFINQKMRPGSGVLSVQVLPDGPTRVLQISDFNQRRV---NRPSPSTEEDPNKEIAQTKFP----EEELEVVVNLEEGVGLSLVN-KLPEELVFATLSGIDVHFTRTAANQVLELTVKNIQVDNQLLGTTHPVLLCVTPGSSESTALDSGPALQVNAVKVPSRLMLTDLFKHLMVTARRYTVIIEEKLLMKLLIFFGYGQTEGEMEKLDENIYEKASE-DPGTPKRYYFENLKISLPQVKLSVFTSHKLPHDLKALKGTLGFPLIRFEDAIINMYPYTRVHPYETQEMVINDILKHFKEELISQAAQILGSVDFLGNPMGLLNDVTEGMNELIKYGNVGGLIRSVTHGVSNSAAKFAGTLSDGLGKTMDNRHQ--TERECIRYHGATSGEHLVAGIHGLAHGIIGGLTSVITSTVEGVKTEGGVSGFFSGLGKGLVGTVTKPVAGALDFASETAQTVRDMASVNN-RLSVQRVRKPRCCK-GPQGLLPRFSSLQADGQEQLFHLTDNIHSEYFIAVEP-----IDTYCVLISSKVVYFLKPGEFADREAIFLEVKYDDLYHCLVSKDHGKVYVQLTKKAESTSSGVAIPGPSHQKPMVHVKSESLAIKISQEINYAKSLYYEQQLMLPPSENEDSLLLDS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VU08-1", "uniprot_id": "VP13D_DROME", "id": "Q9VU08-1", "name": "Intermembrane lipid transfer protein Vps13D", "aln": "MLRDLITWVLNTYLGKYLENLNSAQLSVALLSGEVELENIPIRKDALRSFNLPVEVTAGSIRKIKLQIPVRQFRTSPWCISIEGLFCIICPKNLDNWDYEKEKLQDLEYKLAVLDTAEAGWRSEKGKQMESYYFSSYNNWLKYGTNMATNIIDNIELKISDVHFRFEDIVDTGKSKICTGIKIGSLTAQSCDCDWTNGSYKMNNNEMNYKLVELKELSVYWDLLHEDIKCQSYSNQEILEKMHSTCELRSHNFIIKPICATARWKRDKCQQVIRTKDKPRVSCELLVPEVVIDISKVQRLQMLDKLSEIRQVKEVRQYRLKRPTCTVESNPIAWWKYATICHGFDFKKNEE--KWLMLKENLRYMLLYKSIILNPNE--NLSAADKEFKAYIESDRKISDLTIMRRICFEKVFTKGFAFESQNEQGKN------------------------MLFHWFPNWMGWYANSPSTPNNEQDE------------SLKHLEDDILVALENSLQNSSDLKSDAVFGHFSIKLLKGLVILQTEDKLNDGRNKS--MEMQFNNFSAYLQLSPQLTSYTVGISLQEVYLIDKTSSDTMHNYLIKPQTG-------------NTATPNQLVKNAALQEDILFQLQYEN---CNHLRFQLNIKSKGLDLIYNEDAIQWLLDFLAD-------------------SNSFKYSPRNRVAKKTDFMKNWNEMFSGNEVN-RKIWMFEIEIFAPRIIFLENYKVSNSLMVLLDFGKLEMRKMEVKRVIPVIESAVTENTSDDDETYLTPCSTPPASEKSGS---ESPTLLENPKTESFLNKNVQLEYVLHNKIYDKYLINFTNLQVLVCKYEERWQACLKTSSN-FHLIDKFNINLTLEQRNIFTVDPEYPSFMLFGTCPTILIHGNEELINNCCNIMKPIIKASKEMEN--------------------------------IYRGGNTIYASERIKNLAEDDRSRVVIEFVMDQLVIEMQSTERSIAELQIIGARAGLTKEPHETNISMSVHGLLLVDAIQSFGPDFELLVASHRHVGMDSLSGSLKHSAIVSPTSPGSPNFFDRATSPHMITKAVQNIKMGDRSTEFCDDEDSTALISVDIKIVPPNESNSMQLHTTSITFNSLDIIANQDTIIEILNFAKRTLLAQNIFPSESPESPKEATEAPVDVVDQVDHKSHNEIFFDFFRLNILLLYTIK----RDKFNVGRKVGTVTLTEAKINASFQSDLSIIGSLGGIQVIDITSEAFCHPRILSVGRDQILRASDTNKQTVLSQLSNEIYSNNYNEETKSDESDAISFQSHWSDKTTCTFQMRMASASYTHCPRFLRDVNACITYFKRSLREFATSIGNKATDMAKEFVQQVRAVEQIGPVY------------------------------PQRNRQDNWLDIIISSPIIILPISNTSTNVLIANLGKISCSNAVKCDSDEFNESYTIEIKNTYVYSLNIDEGEYSFNVHPAKNKD-------------------------------AIPILHDTAITLQLYAG---------YSDDNDEDKQLNRFSIKGSMVEALKVSLNRKQYELLLESIR--------------------------------------YATNFSNEVLNESDELDQNGDIEPTAN----IDAESIISTTIQFSVPVFQINLQNEYHN---DLINLTFKNFNVKHISKG-FDKDVEVVLKSVLMEDLKS-DLTSPFRNMVTS--VDLEQKIKKNEMTSSSCP-----DLPSYCNSLKNRSSSVPSCFYNHMQVKVFGGDQKYTSSNKNELGKKKES-----------------------QTLVIYKSHTGRSAQNGKLEQTSSIQFNCLNLAICVERWYTIFDFFGLVSVDN-------------------VNEKYPEEMKLVEKHIDKVCSKLKVSIRSFNFTLIRNESLLSRVNVSNAVFMILQDPYSKIVEGCLGSVSVNDLTKYGNIYKQKFLTSGTEALNFVYKKKLVDLEALNTLDTDSTLRINMSAVHYIHTKRFSTELHVFVKDLLQLQTPVIRKLKKHG----SEQNMRPSKMKLVIQADSPVIVLPSSYNRNEVIIAYLGQFSLKNSFHFASDNNIISKMSATPSKDE---------------------------------------------------------------------------ILDVMRIDLVNINLFSGERSSMK---AKADQEKDRIIIADMNFLRLGQPFFNESCFLHLQLERNLSADAHRVCPDISVQGTFSKLSGIINIQQYKLIRSFLNNNIGEQTDDIYMNYHNNSCTSIERLSTINLMPKNEVSKIVSILISIRILLEDVSLLLALNTSQSAAIEPLACIHFLKSTLEIDLFSDGSQDIDLISSNILIVDERNESD----KSNENVFKNILEPSKKEVRIENSVQVEVHCRKKATFSKYTIMLNNMRVFALLSFLDQLKSYLQEDS--------------------------PAPVVNNAANQIAQKPQIDTSISTEYVVNITDSEIIFAEECSRLDSNAIILKSTTVICYKPNSNIVPLSLDINHLEIFSCTLDAEEESALSIIDPFTLIIELRSN-------------------CLNILIQKHLNIRLSYVDVKLFSRMARLLPTQTSRPKNVISKADSDLEKAAP----------------------------LVAMGFEISDCLYAMQINNWRINDAAIWLSQQKQNTYRN--------------PALEMKTAVVDASLISVFIIDDCMDADVPLLEVSLSKFLLNFTFQTQDPNPKETNIRHYSLGNIDTEVSVNYYNRRLSGWEPVAETWESNLNWKYTKGHLDNKKRFEIGISSKQMLKLNVTSTFIELFHMVLKNWTNDFND---------------------------------------------------NGAKNFRQRSPFIPFALQNLSGTPLLFKPIYAP--------------LGDLTRSDLQQVELIKNWYSVQPNETKTFDFSQKSKLRHVHSHQLNLHQIFVQIHGWTLIGPISVDKVGMFFRTTKLDS-----------------------QFLTKSRIVFDISLIGSAQKLIKVKSSLGVINKLDRNVFLKMTLKGTHSDGLSSISVIKPNDELSVPLKFIDASLYVAHN----------TSESDAYEDTGFSNEEILWKACGKDD----TRQLLAGYDTNKSILYTFVNISREIYHCKEQNLPGHKITLLPPLKINNMLCCDLMFKIHEHATG-RINSSESVNIYNVNICQPLNLSITLDNFQLSGQLKIPVSHRGVIEPKLKLIDIQKRELHVRVSIQSVPGKGMELYISAPVWIINKTGLPLIYKQEGTSHTAAGQFEEHETARQVAPLMFSFSDQEGSPALVLRLGKAYGSN--NMWCKSFSTHKDLADRDLRAENTKG----SYAIGISVRRGRGLYACTTFVTLSPRFHLHNRSGYKLEFMQLCDIVNYDRPDPRKIISAPVDCNFAFHWPNWDQEQIICVRIPEIECCCWSKGIPIKDVQSLYINVRNEWGEMFFLRLEIISKDATFILLFTDARTLPPPIRIDNCSEVVINFSQL-RSKPVWITPVRPQSSLSYVMDDPLGQQILLMEAPGGNMIEFPINNKNN-IKKTLTYTNFIYIAFQGTFERSNEEEN-----------THRQLVLGVRGKKVVIVEKNSGDRSQLWLMNSNGQLEHEGSTPPIQTNDANAVR-------LVLDLEKAPNPMEFTNLVVRTPNKQRVTTQTWRFENGRLMCHAN-MCVQSRFGESGLKPNYEAVVGRTENRASSSKQIPIGQHIVAQKLRPGSGQLELSTKMDGPISTIEICDIKIKQNSVFLTPDLLWMHASLNNRQITDKGKVSFVHEYLINVELVKGIGISIIARKPCEEIMFISLDHINCDIVQSALENSLDLNIAYIQIDNQLLDAVSPIALHTQTS---NDLEETQNAVVLKLKMLPSPNKNAIIFKYLTLDLKPSTASLEEKLILKVASFLGYGKINRQNLSVQYQFENTDDKPFLQDMKRYYFENLSIGATQVRLSAFTSSKLPVELHETKKALGLTLIKFEDALIELDRYSDKLHFETMDVYRKELKKHYINQVKWHAAAILGSVDFLGNPLGFANDLSEGVSGLIFEGSVKSLVKNVTHGISNSTAKLTETLSDSLGKVVLDDHDNETRQRILELQSNTSGGHLAAGLKGLGFGLLGGVTSIVRHTYDGATSDG-VPGFLSGLGKGLVGTVTKPIIGVLDLASETASAVRETS-RDSHRNAPERKRLPRCVTGAPGGLLPLYSNRQSKGQQYLYLINQKNFSEKIISYEPNLWSDKEARLRLLVSTEYVRIFSLSDANPTIMFECHVSEILSCHPVVTNAGTTPTTSSRASASHYIEISTNLPKITRPRIRCRSEECAEAASRCINYAKSVFDEREHAVL------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**..*::**********:.***: ***:***.* *****:*::****: ::**.**.** * *:.****. : : .** *.:. * * * :::: :*: : * * :*.: * *: . *: * . :.:.*.*::******..**:**** . . . . *: * .:: *.. : .: : * ::: *:*:*** : . *: * * : *.*:::::*: *:. :*: .:: :*::..**:. :: : : : :*::* *:: *.*: : :. :* :*. ::. * ** :* .: .:::::.. .* : .. * *.. .: : **. ::. **.::.:.:* *:*. . . .: ** .* * ***.* ***. *:.: . . :::: . :: .: : * :*.::..:* :. * * ::: .:* ::::*.... : *: * : : * ::* * ::..::. *: *:. .:: . . :*:: **. .::. :*.:.: *::*** :**: : :*: . . : : : :: .*::: :. :.:: *: :: * * ..::* **::** ::: .:.::*::*:*:: : : : . . . : .*: : ** :*** : . . : .: :: ::*::* :.* :**::* : .:.*: . . . *:::***: * **:* :* **::*. :* *. * : :* * : :. . : : .. . : . ::: *: .. . : . :: ** :: : : ::* * *: *:::*:.* :.*.*::: :*::**** ***::*::*.**:**:***:::.:* :***:.* **.* * . ::* * :. *. . . *:. *: .*.**** * :*::*:: * :::: :: * . : * : .:.*: .::.***:*** *: . . * *:.*.:: :*:*.*: * :.: **** :*::*:*.: ::*:* . .. . :. : ::*:** .: * ::::*** *.*..:**:::. . .: .:* : .: ..*.: : . : : .: . *:: *.**:: :* .::*:.:**.* .* * :... : :*:*: :**:* : . . *: **::::* : : : : . : ::*.:*:.::* * : ** :*::: . : .. * . . : :: . * :. :*::*..: .*:.* *:::: .. .. .:::.*:*:***** . : * :: ::.* . ..: :* *.*** . .** : ... . * : : .. .. :. . . . : ::: : *. .: . : :: .::****:: * :: * *:****: *. : * . .: : * :**.:.::*:.:.* : . *::..**: . : . ::*.:**:*:.*** :*::*:::* * * *** : * : : : * : :.*::*:*:**:**.:*: .*::.: *** : *: :: * ::: * *:*.:**:::*.* . :.:*:* **:: ::* * *. . :* . :** : :** ::::*:.** . : . . :::.. . : * .::.* * *:*::****. : :. .*:*::*.:*.: ::: :*::**.:*::*:** ::: *. : : . :* * :.: : : :*** * . . .** :.* *..* : **: ::.::*:* .:: * * .. . ***. *::*::. . *:*:*:* *.. * :*::***:*** ::.:* ::.:*: . .*:... .. : . * :*:*.:*::. *: * :*:******.***: ***. *:* .: :*:*** *. *.::****:**. : :** .. : : *:***** **:** :*: :* :. * * :** .** *: . ::..** ** :: : .* :. . :.*. :.: :****:*.**** *:::*:: . . : * :* :**** ******. *.* . :.*: . : *::: :* *.:*:**.::: : . .* *: . * ::*.**:*:**:* :* .: * .: :. : : . ::.. :.:* .* ..* .*:*. : **** *:*:*.:**: *:: ** : *:****** *** : * . *. *:** ::: ***:*:*.*:*:* * *:*: : ::: : .* :. * *.: :::**:: . * . : :.. . .*..: :: . :. :: . ..:: : : . ***.* ***.: : *:* *:* : :: . ::..:.. : .: .* :::.: *:** :. :* ** . :. : ::* *:.:* * : : * . .::: **** *: ********::*:. . ********* **.::**:*.::*:* . .:*:*:. .: **:.** . . . * ::. : . * ***.*::*:* * * :* ::**: *.*:*.:** * * . . .:* **: .....****. * :*::***: :: * ** *: ::. :*::**:*: *: **** ** :.**. : *:*: ****:**** *:* : * * :. * *:* .* *. *:* : : . *.. *. : : . * * ****** **. :: :. * : : ::*:: :*:.*.***** *...* * ****: * .... * * : * . : *::* *: :* ***** *..* * * : ** * *** . *.*:* .:. . *:: **:***** *.: . *** .::* *: :: . . . .: . .* : *.* *:*:*:: * **::* :* *: . .: * .: *:*.: :*:****:.:. *. * . . . :: *: :: .** : ::*:* : : *. :****::*: *:**.: : : . : :: :. : *******.*. .*::**.*** *** :*: * :**:.**:****:*:: :: :** :. ::: **: ::: :** ***********:*: **::**:. ** *.* .*::.****:***:**:: ****.***.: : *: :.:. :. :. *** **.**::**..*::**:**:: * :*..::* *.**:**************: *.**:*****.:**: : .. * :* * *** . .* **** :*. *:.**: *: :.:: .* :*: * :: *: *. : . . : :* : * * .: *.. . :: : . :: *. :* :: :** * *: ******:: *:: : ", "identical_positions": 1009, "similar_positions": 1404, "identity": "22.31%" }, { "cls_id": "homologset.agr.RGD:1308404", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8NC06-1", "uniprot_id": "ACBD4_HUMAN", "id": "Q8NC06-1", "name": "Acyl-CoA-binding domain-containing protein 4", "aln": "MGTEKESPEPDCQKQFQAAVSVIQNLPKNGSYRPSYEEMLRFYSYYKQATMG-PCLVPRPGFWDPIGRYKWDAWNSLGKMSREEAMSAYITEMKLVAQKVIDTVPLGEVAEDMFGYFEPLYQVIPDMPRPPETFLRRVTGWKEQVVNGDVGAVSEPPCLPKEPAPPSPESHSPRDLDSEVFCDSLEQLEPELS-----------------------SGQ--HLEESVIPG---TAPCPPQRKRGCGAARRGPRSWTCGCWGQFEHYRRACRRCRRGCRAWR----ACPGPLS----------SLTLSVRLE-------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DGF9-1", "uniprot_id": "ACBD4_RAT", "id": "Q6DGF9-1", "name": "Acyl-CoA-binding domain-containing protein 4", "aln": "MGTEKE--EPDCQKQFQAAVSVIQNLPKNGSYRPSYEEMLRFYSYYKQATAG-PCLVPRPGFWDPIGRYKWDAWNSLGKMSREEAMSAYITEMKLVAQKVIDTVPLGEVAEDMFGYFEPLYQVIPDMPRPPETFLRRVTGWQEPAVNRDVQAAPEPSHPPKEPAPPSPESRLPRDLDLEVFCDSVEQLEPELVRVPVLSPVPAESELPHLHTGTGDSAQRVWAEQKEAAGRELTTRSSPESPEGFGGSLMGPQELDRWLVGTVQAMQESMKDVHRRLQILE----SKPQPLEQQRSPRTRPWPLGLSTPTLLFFILWPFVVQWLFRQFRTQRR---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VQI6-1", "uniprot_id": "Q9VQI6_DROME", "id": "Q9VQI6-1", "name": "ACB domain-containing protein", "aln": "--------MAAIEERFQAAVNVIKGLPKNGPYQPSTSMMLKFYGLFKQATEGRPDVDKKPGFWDIVGKAKWQAWNDNRHLTKEEAMQRYVESL----QEIIETMSFTENVQNFVGSLDSLGNISLDELELVSPGMKELAESHPNSPFHSRTNSPQHGSSCNGEPEPEPQATSTAPLATSETIKENGHSSPPLTNGYGPKPTASYTQHDTHNFTSNSSVAIVDPSDDEYDDPYDLSHELTQAIGQNTDLLRQIQAAITRMNSDVGAVQQRVRSLEQSLNELRSGQKAAKGTVAQPRSLPAWWPFRNISPLWFAVLILWPFLVRRFARMLQSNPQRRH", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :::*****.**:.*****.*:** . **:**. :**** * * : :***** :*: **:***. ::::****. *: .: *::*:*:.: * .:::.* ::.* :: * . .. ::.:: : . .: : . *.*:: . * . .. : .* * * .:. . : .: : . . :. : .: . . : .: :* ", "identical_positions": 55, "similar_positions": 87, "identity": "16.37%" }, { "cls_id": "homologset.agr.RGD:1308406", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LVF6-1", "uniprot_id": "A0ABK0LVF6_RAT", "id": "A0ABK0LVF6-1", "name": "Condensin-2 complex subunit G2", "aln": "MEKREAFIQAVSKELVEEFLQFLQLDKDPSDPFSLSELLDELSRKQKEELWQRLKDLLTEALLESPVDGWLTAEVQGADDMEPEHSPKMKKSVEITYAIVTVILASVPIINEHENYGALLECAVILNGILYALPESEQKLQNSIQDLCVKWWERGLPAKEDMGKTAFVMLLRKSLET-KTGADMCRLWRIHQALYCFDYDLEESREIKDMLLQCFINVNCIKKEEGRRFLSYLFSWNIDFIKMIHDTIKNQLPGLQKSLMVHIAEIYFRAWKKASGKILETIENDCIQDFMFHGIHLPRRSPVHSKVREVLSYFHQQK-VRQGVEEMLYRLYKPILWRGLKARNSEVRSNAALLFVEAFPVRDPNFIATEMDSEIQKQFEELYSLLEDPYPWVRSTGILGVCKITSKYWEMMPPTILVDLLKKVTGELAFDISSADVRCSVFKCLPIILDNKLSHPLLEQLLPSLRYSLHDNAEKVRVAFVDLLLKVKAVRAAKFWKICPMEDILVRLEMDSRPVSRRLVSLIFNSFLPVNQPEEVWCERCVTLIQMNRAAARRFYQYAHEHTASTNIGLHLCLSRVSLPLPQSAWSRCSVFSLTKLIHVIRHCLNACIQRTLREGAETHKECE---KENASVLDKTLSVNDTASMAGLLEIIVILWKNIHRSLENNKEAKAYTINKFASVLPEYLKVFKDERCKIPLFMLMSFLPASAVPVFSCGVISALRNQEESVTGRSYCTLLDCLCSWGQVGHVLELIVDWLPTVPPQAKS-NLASKRKVQINDMCSVKPKLALLYMEYLLTHPKNRECLLSAPQKKLNQLLKALEGSKADLESLLQSPSGNPLN--KATALHAFGLYCRMSVHLQYKFCSEEKIHLSILSDTGSWLENKVLPLLEDQEEEYLKLQRDVYQQIIQTYLAVCKDAVMVGLGDPKFQVQLLQRSFGIMKTVKEFFYVSLLLGILKEIAGNSMIYRTDSDE-KVTVLFDLVQEVFQKMLECVACVFRKQPEESLQLFHSVQTPLHEFITTIQSWHQDTAVHHAVLSTLIAAPVVEISHQLQKVSDIEELTSPQCLADLPPFSRSLMGVIMKSSDVVRSFLDELKTCVTSGDIEGIVCLTAVLHIILVFNRGKHVSAKVQEVAASVNRKLKTFMEITLEE-DSLERFLYESSMRTLGEFLNS------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6DFV1-1", "uniprot_id": "CNDG2_MOUSE", "id": "Q6DFV1-1", "name": "Condensin-2 complex subunit G2", "aln": "MEKREAFIQAVSKELVEEFLQFLQLDKDSSNPFSLSELLDELSRKQKEELWQRLKDLLTETLLESPVDRWQTVEVEGADDMESEHSPKMRKSIKIICAIVTVILASVSIINEHENYGALLECAVILNGILYALPESEQKLQNSIQDLCVKWWERGLPAKEDMGKTAFIMLLRRSLET-KSGADVCRLWRIHQALYCFDYDWEESREIKDMLLECFINVNYIKKEEGRRFLSFLFSWNVDFIKMIHETIKNQLAGLQKSLMVHIAEIYFRAWKKASGKMLETIEYDCIQDFMFHGIHLLRRSPVHSKVREVLSYFHQQK-VRQGVEEMLYRLYKPILWRGLKARNSEVRSNAALLFVEAFPIRDPNFTATEMDNEIQKQFEELYNLIEDPYPRVRSTGILGVCKISSKYWEMMPPNILVDFLKKVTGELAFDISSADVRCSVFKCLPIILDNKLSHPLLEQLLPTLRYSLHDNSEKVRVAFVDLLLKIKAVRAAKFWKICPMEDILVRLEMDSRPVSRRLVSLIFNSFLPVNQPEEVWCERCVTLIQMNRAAARRFYQYAHEHTASTNI--------------------------AKLIHVIRHCLNACIQRTLREGSEAHKECE---KENASVLDKTLSVNDTASMAGLLEIIVILWKNIHRSLENNKEAKIYTINKFAAVLPEYLKVFKDERCKIPLFMLMSFLPASAVPVFSCGVISVLRNQE-SVTGRSYCTLLDCLCSWGQVGHVLELIVDWLPTVPPQAKS-NLASKRKVEINDTCSVKPELALLYMEYLLTHPKNRECLLSVPQKKLNQLLKALEGSKAELESFLQSPSGNPLNFNKATALHAFGLYCRMSVHLQYKFCSEEKIHLSILDDTGSWLENKVLPLLEDQEEEYLKLRKDVYQQIIQTYLAVCKDVVMVGLGDPKFQMQLLQRSFGIMKTVKGFFYVSLLLGILKEIAGNTIIHKTDSDE-KVTVLFDLVQEVFQKMLECIACIFRKQPEESLPLFHSVQTPLHEFITTIQSWHKDTAVHHAVLSTLIAAPVVEISHQLQKVSDIEELTSPQCLHDLPPFSRCLVGVIMKSSDVVRSFVDELKACVTSGDVEGIVCLTAVLHIILVINKGKHISAKVKEVATAVYRKLKTFMEITLEE-DSLERFLYESSMRTLGEFLNP------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86XI2-1", "uniprot_id": "CNDG2_HUMAN", "id": "Q86XI2-1", "name": "Condensin-2 complex subunit G2", "aln": "MEKRETFVQAVSKELVGEFLQFVQLDKEASDPFSLNELLDELSRKQKEELWQRLKNLLTDVLLESPVDGWQVVEAQGEDNMETEHGSKMRKSIEIIYAITSVILASVSVINESENYEALLECVIILNGILYALPESERKLQSSIQDLCVTWWEKGLPAKEDTGKTAFVMLLRRSLET-KTGADVCRLWRIHQALYCFDYDLEESGEIKDMLLECFININYIKKEEGRRFLSCLFNWNINFIKMIHGTIKNQLQGLQKSLMVYIAEIYFRAWKKASGKILEAIENDCIQDFMFHGIHLPRRSPVHSKVREVLSYFHHQKKVRQGVEEMLYRLYKPILWRGLKARNSEVRSNAALLFVEAFPIRDPNLHAIEMDSEIQKQFEELYSLLEDPYPMVRSTGILGVCKITSKYWEMMPPTILIDLLKKVTGELAFDTSSADVRCSVFKCLPMILDNKLSHPLLEQLLPALRYSLHDNSEKVRVAFVDMLLKIKAVRAAKFWKICPMEHILVRLETDSRPVSRRLVSLIFNSFLPVNQPEEVWCERCVTLVQMNHAAARRFYQYAHEHTACTNI--------------------------AKLIHVIRHCLNACIQRAVREPPEDEEEEDGREKENVTVLDKTLSVNDVACMAGLLEIIVILWKSIDRSMENNKEAKLYTINKFASVLPEYLKVFKDDRCKIPLFMLMSFMPASAVPPFSCGVISTLRSREEGAVDKSYCTLLDCLCSWGQVGHILELVDNWLPTEHAQAKS-NTASKGRVQIHDTRPVKPELALVYIEYLLTHPKNRECLLSAPRKKLNHLLKALETSKADLESLLQTPGGKPRGFSEAAAPRAFGLHCRLSIHLQHKFCSEGKVYLSMLEDTGFWLESKILSFIQDQEEDYLKLHRVIYQQIIQTYLTVCKDVVMVGLGDHQFQMQLLQRSLGIMQTVKGFFYVSLLLDILKEITGSSLIQKTDSDE-EVAMLLDTVQKVFQKMLECIARSFRKQPEEGLRLLYSVQRPLHEFITAVQSRHTDTPVHRGVLSTLIAGPVVEISHQLRKVSDVEELTPPEHLSDLPPFSRCLIGIIIKSSNVVRSFLDELKACVASNDIEGIVCLTAAVHIILVINAGKHKSSKVREVAATVHRKLKTFMEITLEE-DSIERFLYESSSRTLGELLNS------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FH61-1", "uniprot_id": "CNDG2_DANRE", "id": "E7FH61-1", "name": "Condensin-2 complex subunit G2", "aln": "MSKRKQFLDSVHHEHVQDFLNFIKLHKDGADPFDLAEILAELQKSQRQDLWDRQLKLLQHSLTVSPSERWITGAEEDAGDMEVEVSEEQIQTMAVIEGVTIVSTVSVDALQEKDNYTTLLKCAQMLNAIESALPLSQTPLQQAIHWLFECWWRRDLQGKEELGWTAFLVCLENTVTLDKPVSELRRLCSLREVLLSVDFGSEKGQQVIDPLLQCFFRASHIKQEEGKRFLAFLFSWNDNFIRMIHETIKNQLQFFPKTLSVHVAEIYFRAWRKASGPFLEEIESACIQDLMQHALLLHRNSPVHSKVRQILTYFHKQK-FREGVDEMLHRLYKPVLWKALKATNAEVRANATLLFTEAFPIHDPNMSSEMVDQAVQKQLDLLFALLDDPQPLVRSSAVLGVCSVLARCWEVIPSAVITDLLEKLILQLANDTSSPDVRCSVFMCMSIILDNSLSHPLMEKLLPALKSSLHDSSEKVRVAFVGMLLKIKAARAAKFWKVCSLEHLLARLEMDSAPVSKRIVNLLFNSFFPVNQPETVWCERCVTLIQTNPGAARKFYQHAYLYTAPANI--------------------------VKLMLVIRKCLNVCIQN---AGDEEFASSN---KENSTLLEDVLSVQDTSSMASLLEILVILWKSVQKSLMANQEAFKYTTAKFGSSLPQYLKIFQEERCKAPLILLASLLPASALPALRSKVMSHLRSLKAGAAVTTYSQTLECLCSWGQISHIVELIENWLTEAAPVKEQGDEESTGKVHFDVLEESKPDLGLDYLDYMLLRPKTRECLLTLPLDQMRPLHKALNKWKSLLFSSLS--GSEVSVAAIETALRAFIFHGRLCIHLQHKFP-EEREFLKSLEHSVSWVEKRVLPFLVNSSSD---QQLSLSTKIVESCVTVCKNVLRVSVGDSDFRDHLLQHVASVLQTEKGYMCIPHLLALLTEIAHGCLSQKAEGQEDQLSLTIRILTNIFQKVVEILAHRLRKDKEEGQELCCSSEEALHDFLLVTKFTSERSEFMTGVFSSLCAAVIIDISRPLQKISHVEELLMPETVNDLPPLSSTILKVTLGCPAVTRFFLSELSSSIESEAIDSITQWAAVTHILTIIKESDAFIVELKDIAGSVRRQIQNYYNSISENSDDIQRTIYESTVKMLNDVLISCQQTNN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.**: *:::* :* * :**:*::*.*: ::**.* *:* **.:.*:::**:* .** . * ** : * . :. .:** * . : ::: : .:. * .** ::* :** :**:*. :**.* *** *: **.:*: * **.:.* .**: * ***:: *..:: *. ::: ** :::.* ..*:. *:. :: * **:**:. . **:***:***: **.** :**:*** ****** : *:* *::********:**** :** ** ****:* *.: * *.********::*:***:** .*:**:***:*****:**:.*** *:***:**:***.****::***: : :*. :***:: *: *::** * ***:.:****.: :: **::*. :: *:*:*: :** * **.******* *:.:****.*****:*:***:*: ****.:********.:***:**.*******:*.:*.:*.*** ** ***:*:*.*:****:****** *********:* * .***:***:*: :** :** .**: ***:***.***. * . : *** ::*:..***:*.:.**.****:*****.:.:*: *:** ** **.: **:***:*:::*** **::* *::****:* : . *:* **. : ... :*. *:*******:.*::**: :**. . :. : *. :*.:. **.*.* *::*:* :**.*****: * .::. * ***: *: * * *. ..: :* :** :: *:.:***:** * : .*. *..: *:*.::*.:: :...: : : :*::: ::***:.: *.:** .*: :***: .:::* * :: :. ** :*.**: . : :::.:* :::: : : ::***::* :* :**: **. * * : .**:*: . : : . .*:*:* *. :::**: *:*:*.:*** *: : ****:* :: : : .. *.* *:.**.:.: * ::.*. :*. **: ::: .. :::::* :* *:::.: : *: *.::* :***: : *.:.* . ", "identical_positions": 475, "similar_positions": 403, "identity": "40.29%" }, { "cls_id": "homologset.agr.RGD:1308407", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "E7F6Y5-1", "uniprot_id": "E7F6Y5_DANRE", "id": "E7F6Y5-1", "name": "", "aln": "MSLFLNALAFICKVLTLPLFVGERVGLLSFY-KRLYPRLLSSFTIAYNELMNDKKRELFLNLERFQPSKGSLRILEVGCGSG-ANFEHYPTGSKITCTDPNPHFKTYLEKSMEKNEHLVYDSFIVASGENLQAVEDSSVDAVVCTLVLCTVKDTNKVLQEAKRVLRPGGAFFFLEHVVSDPSTWAYFFQHVLQPFWYYLQDGCEAIR-----------ATWKDIDNAGFSDVKLRHIQ-------------------APL-FFMIKPHIIGYAVK-------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9Q726-1", "uniprot_id": "A0A8M9Q726_DANRE", "id": "A0A8M9Q726-1", "name": "", "aln": "MSRFMDACALSFKVLILPLYIAEHVGLLSFF-KRVFPMIQYKATDWYNNKMNDKKRELFRNLERFQPPEGSLRILEVGCGSG-ANFEHYPTGSKITCTDPNPHFKKYLEKSIEKNEHLEYDNFIVASGENLQAVEDSSVDAVVCTLVLCSVKDTNKVLQESKRVLRPGGALFFLEHVVSDPSTWAYFFQHVLEPLWYFFGDGCEVTR-----------ATWKHIEAAGFSDVKLHHIQ-------------------APL-FFMLKPHIVGYAVK-------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "G3X9G9-1", "uniprot_id": "G3X9G9_MOUSE", "id": "G3X9G9-1", "name": "", "aln": "MTLAVQAMRLVVCIVAFPIFLLNILGMWSWVCKKCFPYFLKRFAMIYNWKMASLKQELFSNLQEFAGPSGKLTLLEVGCGTG-ANFKFYPPGCRVTCIDPNPNFEKFLFKSVAENRQLQFERFVVAVGEDMHQVTDGSVDVVVCTLVLCSVKNQEKILREVCRVLKPGGAFYFIDHVADERSTWNYFWQQVLARVWFLAFDGCNLTR-----------ESWKAIEQANFSKLNLQHIQ-------------------APLPLTLVRPHIYGYAVK-------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6A343-1", "uniprot_id": "A0A8I6A343_RAT", "id": "A0A8I6A343-1", "name": "", "aln": "MTLAILALRLVVCTLSFPLFLLNLIGVWSWVCKRCFPYFLKRFTVMYNEQMATRKRELFSNLQEFAGPSGKLSLLEVGCGTG-ANFKFYPPGCRVTCIDPNPNFEKFLFKSVAENRHLQFERFLVAVGEDMHQVADGSVDVVVCTLVLCSVKSQEKILREVCRVLRPGGAFYFMEHVADERSTWNYFWQQVLDPVWFLVFDGCNLTR-----------ESWKTLEQASFSKLKLQHIQ-------------------APLSWALVRPHIYGYAVK-------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H8H3-1", "uniprot_id": "TMT1A_HUMAN", "id": "Q9H8H3-1", "name": "Thiol S-methyltransferase TMT1A", "aln": "MELTIFILRLAIYILTFPLYLLNFLGLWSWICKKWFPYFLVRFTVIYNEQMASKKRELFSNLQEFAGPSGKLSLLEVGCGTG-ANFKFYPPGCRVTCIDPNPNFEKFLIKSIAENRHLQFERFVVAAGENMHQVADGSVDVVVCTLVLCSVKNQERILREVCRVLRPGGAFYFMEHVAAECSTWNYFWQQVLDPAWHLLFDGCNLTR-----------ESWKALERASFSKLKLQHIQ-------------------APLSWELVRPHIYGYAVK-------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P38892-1", "uniprot_id": "CRG1_YEAST", "id": "P38892-1", "name": "Probable S-adenosylmethionine-dependent methyltransferase CRG1", "aln": "------------------------MPKTSYLNKNFES-------AHYNNVRPSYPLSLVNEIMKFHKG-TRKSLVDIGCGTGKATFVVEPYFKEVIGIDPSSAMLSIAEKETNERRLDKKIRFINAPGEDLSSIRPESVDMVISAEAIHWCN-LERLFQQVSSILRSDGTFAFWFYIQPEFVDFPEALNVYYKYGWSKDYMGKYLNDNQREILLNYGGEKLRSLLSDRFGDIEVTIYSPSDPNASTVTAENSQFLWRAAITLNQFKEFVKSWSIYTSWARDNPSKPDIADIFINELKEICHCEDLNVPLKIEWSTFYYLCRKRE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *: *. . ** .*. :: .* ::::***:* *.* * .: **.. : . *. :.. *: * **:: : *** *:.: .: : :::::: :*:..*:: * :: : : : * * . : : *..::: . *.: .: .: .::: ", "identical_positions": 31, "similar_positions": 71, "identity": "9.57%" }, { "cls_id": "homologset.agr.RGD:1308408", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LGA2-1", "uniprot_id": "A0ABK0LGA2_RAT", "id": "A0ABK0LGA2-1", "name": "Hyaluronan and proteoglycan link protein 4", "aln": "MGLLSGSTSVTLGMEYQLSPVRLVNAVLLGKRLRWIIITVLSTPCAWGLPHPHPARCARVRAAPLMPHAPSSPCRQTPGLRGPRDQLARPLCACAVGKRTGRSAGATTRMACAPGALGHRALWAVAWGLLLLVP-VLAGAQRGRKKVVHVLEGESGSVVVQTAPGQVVSHRGGTIVLPCRYHYEAAAHGHDGVRLKWTKVVDPLAFADVFVALGPQHRAFGPYRGRAELQNDGPGDASLVLRNVTLQDYGRYECEVTNELEDDAGMVKLDLEGVVFPYHPRGGRYKMTFAEAQRACAEQDGILASAEQLHTAWRDGLDWCNAGWLRDGSVQYPVSQAREACG---GSGSPGAGGGTNGGVRNYGYRHNAEERYDAFCFTSNLPGRVFFLKPLRPVALAGAVRACAARGATVAKVGQLFAAWKLQLLDRCTAGWLADGSARYPIVNPRTRCGGPRPGVRSLGFPDASRRLFGVYCYRAPGAPDPAPGGWGWGWAGGGGWAGGSRDPAAWTPLRV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80WM4-1", "uniprot_id": "HPLN4_MOUSE", "id": "Q80WM4-1", "name": "Hyaluronan and proteoglycan link protein 4", "aln": "-------------------------------------------------------------------------------------------------------------MACAPGALGHRALWAVAWGLLLLVP-VLAGAQRGRKKVVHVLEGESGSVVVQTAPGQVVSHRGGTIVLPCRYHYEAAAHGHDGVRLKWTKVVDPLAFADVFVALGPQHRAFGPYRGRAELQNDGPGDASLVLRNVTLQDYGRYECEVTNELEDDVGMVKLDLEGVVFPYHPRGGRYKMTFVEAQRACAEQDGILASAEQLHAAWRDGLDWCNAGWLRDGSVQYPVSHAREPCG---GTGSTGAGGGTNGGVRNYGYRHNAEERYDAFCFTSNLPGRVFFLKPLRPVALAGAVRACAARGATVAKVGQLFAAWKLQLLDRCTAGWLADGSARYPIVNPRTRCGGPRPGVRSLGFPDASRRLFGVYCYRAPGAPDPAPGGWGWGWAGGGGWAGGSRDPAAWTPLRV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86UW8-1", "uniprot_id": "HPLN4_HUMAN", "id": "Q86UW8-1", "name": "Hyaluronan and proteoglycan link protein 4", "aln": "-------------------------------------------------------------------------------------------------------------MVCARAALGPGALWAAAWGVLLLT--APAGAQRGRKKVVHVLEGESGSVVVQTAPGQVVSHRGGTIVLPCRYHYEAAAHGHDGVRLKWTKVVDPLAFTDVFVALGPQHRAFGSYRGRAELQGDGPGDASLVLRNVTLQDYGRYECEVTNELEDDAGMVKLDLEGVVFPYHPRGGRYKLTFAEAQRACAEQDGILASAEQLHAAWRDGLDWCNAGWLRDGSVQYPVNRPREPCGGLGGTGSAGGGGDANGGLRNYGYRHNAEERYDAFCFTSNLPGRVFFLKPLRPVPFSGAARACAARGAAVAKVGQLFAAWKLQLLDRCTAGWLADGSARYPIVNPRARCGGRRPGVRSLGFPDATRRLFGVYCYRAPGAPDPAPGGWGWGWAGGGGWAGGARDPAAWTPLHV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BHT5-1", "uniprot_id": "A0A8M2BHT5_DANRE", "id": "A0A8M2BHT5-1", "name": "Hyaluronan and proteoglycan link protein 4", "aln": "------------------------------------------------------------------------MRRWTSAVKRDSQKRDSCTTARLSLSSNNFIPSQHQTRHCMMMILFLEILTCTLLLLCPFVTSYPADLEKGRRRVVHVMEDDTGAVIVQTAPGKVVTHRGGTITLPCRYHHEPEDIDPNRIRIKWTKVSDAFQFEDVFVALGRQQKAFGSYQERVSLEQAGPGDASVIIHNITLEDYGRYECEVTNDMEDDTGFVNLDLEGVVFPYYPPSGRYKLNYHQAEEVCREQDAILASHPQLHKAWLEGLDWCNAGWLEDGSVQYPISHPRDQCG----------RKDSPPGVRNYGYRHKDDERYDAFCFTSNLNGRVYFLKRFKKVNYLEAVKACQRDGAFIAKVGQLYAAWKIQLLDRCEAGWVEDGSIRYPIVNPRARCGGPDPGVRNLGFPDKKFRLYGVYCFRKNTDIQSTQT------------PTETTSKMANSTRSI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * * .. : :. *. ::**::****:*.::*:*:******:**:******.******:*. . : :*:***** *.: * ******* *::***.*: *..*: ******::::*:**:***********::***.*:*:**********:* .****:.: :*:..* ***.**** *** ** :**********.*******:.:.*: ** .: *:*******: :************ ***:*** :: * *.:** ** :******:****:****** ***: *** ********:**** ****.***** . **:****:* :.: . : . * :. :", "identical_positions": 213, "similar_positions": 90, "identity": "41.52%" }, { "cls_id": "homologset.agr.RGD:1308412", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5BJT1-1", "uniprot_id": "AN34A_RAT", "id": "Q5BJT1-1", "name": "Ankyrin repeat domain-containing protein 34A", "aln": "MLHTEGHALLRAVGQGKLRLARLLLEGGAYVNEGDAQGETALMAACRARYDDPQNKARMVRYLLEQGADPNIADRLGRTALMHACAGGGGAAVASLLLAHGADPSVRDHAGASALVHALDRGDRETLATLLDACKAKGTEVIIITTDTSPSGTKKTRQYLNSPPSPGVEDPAPAPPSPGVCTSPSEVQLQTAGGG-RGLLSPRAQEEEEKRDVFEFPLPKSPDDPSPSEPLPKPPRHPPKPLKRLNSEPWGLVAPPQPVPPAEGRPGLERLAAEFNGLTLTGRPRLSRRHSTEGPEDPPPWAEKVTGGGPLSRRNTAPEAQESGLPSGLRQKLSRMESVELDTPGHFCPDSPESSRLSLERRRYSASPLTLPPAGSVSSPRQSQESLPGAVSPLSGRRRSPGLLERRGSGTLLLDHISQTRPGFLPPLNVSPHPPIPDIRPQPGGRAPSLPAPPHSGAPGSPRTKRKLVRRHSMQTEQIRLLGGFQSLGGPGEPGR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q69YU3-1", "uniprot_id": "AN34A_HUMAN", "id": "Q69YU3-1", "name": "Ankyrin repeat domain-containing protein 34A", "aln": "MLHTEGHALLRAVGQGKLRLARLLLEGGAYVNEGDAQGETALMAACRARYDDPQNKARMVRYLLEQGADPNIADRLGRTALMHACAGGGGAAVASLLLAHGADPSVRDHAGASALVHALDRGDRETLATLLDACKAKGTEVIIITTDTSPSGTKKTRQYLNSPPSPGVEDPAPASPSPGFCTSPSEIQLQTAGGGGRGMLSPRAQEEEEKRDVFEFPLPKPPDDPSPSEPLPKPPRHPPKPLKRLNSEPWGLVAPPQPVPPTEGRPGIERLTAEFNGLTLTGRPRLSRRHSTEGPEDPPPWAEKVTSGGPLSRRNTAPEAQESGPPSGLRQKLSRMEPVELDTPGHLCPDSPESSRLSLERRRYSASPLTLPPAGSAPSPRQSQESLPGAVSPLSGRRRSPGLLERRGSGTLLLDHISQTRPGFLPPLNVSPHPPIPDIRPQPGGRAPSLPAPPYAGAPGSPRTKRKLVRRHSMQTEQIRLLGGFQSLGGPGEPGR", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******************************************************************************************************************************************************************************.****.******:******** **:*********************.****************************************:*****:***:**********************************.***************** ************.********:*****************************..****************************************************************************::****************************************", "identical_positions": 479, "similar_positions": 15, "identity": "96.57%" }, { "cls_id": "homologset.agr.RGD:1308413", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "B2RZC9-1", "uniprot_id": "KTAP2_RAT", "id": "B2RZC9-1", "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit KCP2", "aln": "MVVGTG-----TSLALSSLLSLLLFAGMQIYSRQLASTEWLTIQGGLLGSGLFVFSLTAFNNLENLVFGKGFQAKIFPEILLCLLLALFASGLIHRVCVTTCFIFSMVGLYYINKISSTLYQATAPALTPAKVTGKSKKRN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N6L1-1", "uniprot_id": "KTAP2_HUMAN", "id": "Q8N6L1-1", "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit KCP2", "aln": "MVVGTG-----TSLALSSLLSLLLFAGMQMYSRQLASTEWLTIQGGLLGSGLFVFSLTAFNNLENLVFGKGFQAKIFPEILLCLLLALFASGLIHRVCVTTCFIFSMVGLYYINKISSTLYQAAAPVLTPAKVTGKSKKRN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5RL79-1", "uniprot_id": "KTAP2_MOUSE", "id": "Q5RL79-1", "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit KCP2", "aln": "MVVGTG-----TSLALSSLLSLLLFAGMQIYSRQLASTEWLTIQGGLLGSGLFVFSLTAFNNLENLVFGKGFQAKIFPEILLCLLLALFASGLIHRVCVTTCFIFSMVGLYYINKISSTLYQATAPVLTPAKITGKGKKRN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8INQ7-1", "uniprot_id": "KTAP2_DROME", "id": "Q8INQ7-1", "name": "Protein KRTCAP2 homolog", "aln": "MSASVSSKSTVVSSIISGLLSIVLFGTLRFCSEWFNDSQLRVLLGGYLFSWVFILSLTCVSNAEMVVFGQDFQAKLLPEIIFCLSLTVAAAGLVHRVCATTSVLFSLVGLYFLNRISTKYYSVQVPSVDAPTTRKGGKKFK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* .... .* :*.***::**. ::: *. : .:: .: ** * * :*::***...* * :***:.****::***::** *:: *:**:****.**..:**:****::*:**:. *.. .* : ... .** :", "identical_positions": 54, "similar_positions": 56, "identity": "38.3%" }, { "cls_id": "homologset.agr.RGD:1308414", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZCR5-1", "uniprot_id": "D3ZCR5_RAT", "id": "D3ZCR5-1", "name": "", "aln": "-------------------------------------------------------------MAQLGEQTLPGPETTVQ------------------IRVAIQEAEDVEDLEEDDEGTSARAAGDTARYLSP--------GWGSAS-------------------------------------------------------------------------------------------------------EEEPSRGHS-ATTSGGENDREDLEPEWKPPDEELIRKLVDQIEFYFSDENLEKDAFLLKHVRRNKLGYVSVKLLTSFKKVKHLTRDWRTTAHALK-YSVTLELNEDHRKVRRTTPVPLFPNENLPSKMLLVYDLHLSPKLWSLATPPKNGRVQEKVMEYLLKLFGTFGVISSVRILKPGRELPPDIRRISSRYSQVGTQECAIVEFEEVDAAIKA-------HEFMATESQGKENMKAVLIGMRPPKKKPLKDKNHEDEP----------------------------------------------------------------------AAGTRLSRSLNKRVEELQYMGDESSANSSSDPESNPTSP---MAGRRHVASNKLSPSGHQNIFLSPNASPCSSPWSSPLAQRKGVSRKSPLAEEGRLNFSTSPEIFRKCMDYSSDSS----------------------ITPSGSPWVRRRRQAEMGTQEKSPGASPLLS-----------------------------------RKMQTADGLP-------------------------------------------------------------VGVLRLPRGPDDTRGFHGGHERGRACI----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BN59-1", "uniprot_id": "LARP6_MOUSE", "id": "Q8BN59-1", "name": "La-related protein 6", "aln": "-------------------------------------------------------------MAQLGEQTLPGPETTVQ------------------IRVAIQEAEDLEDLEEEDEGTSARAAGDPARYLSP--------GWGSAS-------------------------------------------------------------------------------------------------------EEEPSRGHSSATTSGGENDREDLEPEWRPPDEELIRKLVDQIEFYFSDENLEKDAFLLKHVRRNKLGYVSVKLLTSFKKVKHLTRDWRTTAHALK-YSVTLELNEDHRKVRRTTPVPLFPNENLPSKMLLVYDLHLSPKLWALATPQKNGRVQEKVMEHLLKLFGTFGVISSVRILKPGRELPPDIRRISSRYSQVGTQECAIVEFEEVDAAIKA-------HEFMVTESQSKENMKAVLIGMKPPKKKPLKDKNHDDEA----------------------------------------------------------------------TAGTHLSRSLNKRVEELQYMGDESSANSSSDPESNPTSP---MAGRRHAASNKLSPSGHQNIFLSPNASPCSSPWSSPLAQRKGVSRKSPLAEEGRLNFSTSPEIFRKCMDYSSDSS----------------------ITPSGSPWVRRRRQAEMGTQEKSPGASPLLS-----------------------------------RRMQTADGLP-------------------------------------------------------------VGVLRLPRGPDNTRGFHGGHERGRACV----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BRS8-1", "uniprot_id": "LARP6_HUMAN", "id": "Q9BRS8-1", "name": "La-related protein 6", "aln": "-------------------------------------------------------------MAQSGGEARPGPKTAVQ------------------IRVAIQEAEDVDELEDEEEGAETRGAGDPARYLSP--------GWGSAS-------------------------------------------------------------------------------------------------------EEEPSRGHSGTTASGGENEREDLEQEWKPPDEELIKKLVDQIEFYFSDENLEKDAFLLKHVRRNKLGYVSVKLLTSFKKVKHLTRDWRTTAHALK-YSVVLELNEDHRKVRRTTPVPLFPNENLPSKMLLVYDLYLSPKLWALATPQKNGRVQEKVMEHLLKLFGTFGVISSVRILKPGRELPPDIRRISSRYSQVGTQECAIVEFEEVEAAIKA-------HEFMITESQGKENMKAVLIGMKPPKKKPAKDKNHDEEP----------------------------------------------------------------------TASIHLNKSLNKRVEELQYMGDESSANSSSDPESNPTSP---MAGRRHAATNKLSPSGHQNLFLSPNASPCTSPWSSPLAQRKGVSRKSPLAEEGRLNCSTSPEIFRKCMDYSSDSS----------------------VTPSGSPWVRRRRQAEMGTQEKSPGTSPLLS-----------------------------------RKMQTADGLP-------------------------------------------------------------VGVLRLPRGPDNTRGFHG-HERSRACV----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1Z9R1-1", "uniprot_id": "A1Z9R1_DROME", "id": "A1Z9R1-1", "name": "", "aln": "MSSPRDKAEQVYEVKAPHAGAEGHTFLVSPVDPTPILAPILTAVPVMKAPDSPASMDKTKEMEELDDEQPSCSSQAVVPLSSSLPCKLLRMHARRSAQALLHQMESMDSQLGSSNGSTSEDTSPSAPPMSPTDHQLVDVGMGSSIGDSDESSEEGDELKPLAVDNHIIAEVDLTERQTTPPAVLSEANLEKFRKHQMDNIYLHPNFTLDASPPPAVAPANSPVLEAKRTHRSFLTMKKEKEVEPPQEKEQEVPVHQEQDTEPQGPNEIDTLDPSLIPS-EELAAEITDAVEFYFSNESILKDAFLLKHVRRNKEGFVSLKLVSSFKRVRQLTREWKVVGDAVRRKSRKIELNDVGTKVRRIEPLPSFD-ETMPSRTIVACDLPLD----------------KLTIEKVSDLFSPCGEIALIRILKPGMAIPVDVRQFMNKYPELQQKECALVEYLESSSARDARHLNGPFQVYEMVAPKKKTGKKAAVIQIAAPVARMVENYRYYNDANYERSRGGSFSGHETVPDLRFKLKRNNSDFQPSYYQQTGPSYHANPYQHYQPRGSIGNQNQEVGPNGFFGYGPRRYSNTSTISANTAAALGDVSPISSAVNSGGNPMVSGISSLQRRLSNCSEQNYTPEVNPSMSRRASNCSETGGVPQRRDSNCSESCPCSRRVSDFAQTTDTSYRKTSVCSNGSCPGNNQNQERRFSNGSMQFERTFSNASESSGFYRRPSNDFNIEREPIQTDQLVGGGGGGYQVWPRRYSNNFQQLSSKLAAYDNAQYIGGRRISTDSGYDRRCSFGSEGFEGSPRSRTGSFLSNYKHGGGDGYDGQPRSRTGSFLDGSPRSRSGSFAQRAAESLVRTPMGPDGSKGFGQRARKFGQTISPVN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : . : . .. :* :. ::: *.::. ..:*: :. :. .* :** * **: *:* . :. * . * *: : *: . *. *** ::.* :*****:*.: ************* *:**:**::***:*::***:*:....*:: * :***: **** *:* * *.:**: ::. ** *. : .:* : .**.. * *: :****** :* *:*:: .:*.:: :***:**: * .:* .* : : . .: * . **.:* : .* : :: .: ::. . : ..: . .: :** *. .*: :. .** . ** .: . : . * :* .** *:.. . * : .. *...* :.. .*: :** *..*. ..* *. . ** . ::. :.:. :. *:. *::.* .* .::* * ***.::** .: : ", "identical_positions": 135, "similar_positions": 182, "identity": "15.25%" }, { "cls_id": "homologset.agr.RGD:1308415", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q498M5-1", "uniprot_id": "SH3R2_RAT", "id": "Q498M5-1", "name": "E3 ubiquitin-protein ligase SH3RF2", "aln": "MDDLTLLDLLECPVCFEKLDVTAKVLPCQHTFCKPCLQRIFKAH-KELRCPECRTLVFCSIEALPANLLLVRLLDGVRSGHNSWRGGSFRRPRILTLQDNRKAKSSPRSLQASPFRLGPTVRIHMDGVPRAKALCNYRGKNPGDLKFNKGDVILLQRQLDENWYQGEINGVSGFFPASSVEVIKQLPQPPPLCRALYNFDLRDKDKSENQDCLTFLKDDVITVISRVDENWAEGKLGDKVGIFPILFVEPNLSARHLLEKSKGHQLSRTKHLSLMSSPSRGKATNTSTLRKSPGSRRKGSGQFAMT--TALNTLNRMVHSPEGHQMVEISTPVLISSTSPSMLTQHGDRADFPASSAGQVSTSHPAPASPGHSTAMVSVP--SSQQHLSTNMFVALHTYSAQGPEELDLKKGEGIRVLGKNQDGWLRGVSLVTGRTGIFPSDYVIPVFSSTARKTSSFPDSRHPTVCTTWALSTS---SVSSQGSFSEGDPRQSGPFRSVFVPTAVN-PPRSTSGPGTSGQGSLRKVRSSMRKNG------------SLQRPVQSGIPTFMVGSLRCSP----AMVIRPQKFQFYQPQGMTPSP--TPIMVEIGSKSISTGEPALTCINRGGKTRTHSAGNSIIMEGKETPIKSEPPPKP------PASAPPSILVKPENSKNGIEKQVKTVRFQNYSPPPTKHSASGPTSGKHEQPATLKGSQPEAVSSEGEMTILFAHRSG------CHSGQQTDLRRKSAFSKTTPPVSTASVSQTLFPSK--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BZT2-1", "uniprot_id": "SH3R2_MOUSE", "id": "Q8BZT2-1", "name": "E3 ubiquitin-protein ligase SH3RF2", "aln": "MDDLTLLDLLECPVCFEKLDVTAKVLPCQHTFCKPCLQRIFKAH-KELRCPECRTLVFCSIEALPANLLLVRLLDGVRSGQSSWKGGSFRRPRILTLQDNRKAKSSPRSLQASPFRLVPSVRIHMDGVPRAKALCNYRGKNPGDLKFNKGDVILLRRQLDENWYQGEINGVSGIFPASSVEVIKQLPQPPPLCRALYNFDLRDKDKSENQDCLTFLKDDVITVISRVDENWAEGKLGDKVGIFPILFVEPNVSARHLLE-NKGHQLSRTRHLSLMSSPSRGKATNTSSLRKSPGSRRKGSGQFSMT--TALNTLNRTVHSPEGHQMVEISTPMLISSNSPSVLTQHGDKADFPTSSTGQVSSSQPAPASPGHSTAMVSVP--SSQQHLSNNMFVALHTYSAHRPEELDLQKGEGIRVLGKYQDGWLKGLSLLTGRTGIFPSDYVIPVFSSTARKTSSFPDSRSPTVCTTWALSTS---SVSSQGSFAEGDPRQSGPFKSVFVPTAVVNPSRSTPGPGSSGQGSLRKVRSSMRKNG------------SLQRPVQSGIPTFMVGSLRCSP----TMVIRPQRFQFYPPQGMTPSP--TPIMVEMGSKSIYTGEPALTCINRGSKTRIHSAGNSIIMEGKETPIKSEPPPKP------PASAPPSILVKPENSKNGTEKQVKTVRFQNYSPPPTKHSASSPTSGKHDHPATLKGSQHEAVSSGGEMTILFAHRSG------CHSGQQTDLRRKSAFGKTMPLLSTASATQTLFPSK--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TEC5-1", "uniprot_id": "SH3R2_HUMAN", "id": "Q8TEC5-1", "name": "E3 ubiquitin-protein ligase SH3RF2", "aln": "MDDLTLLDLLECPVCFEKLDVTAKVLPCQHTFCKPCLQRVFKAH-KELRCPECRTPVFSNIEALPANLLLVRLLDGVRSGQSSGRGGSFRRPGTMTLQDGRKSRTNPRRLQASPFRLVPNVRIHMDGVPRAKALCNYRGQNPGDLRFNKGDIILLRRQLDENWYQGEINGISGNFPASSVEVIKQLPQPPPLCRALYNFDLRGKDKSENQDCLTFLKDDIITVISRVDENWAEGKLGDKVGIFPILFVEPNLTARHLLEKNKGRQSSRTKNLSLVSSSSRG---NTSTLRRGPGSRRKVPGQFSIT--TALNTLNRMVHSPSGRHMVEISTPVLISSSNPSVITQPMEKADVPSSCVGQVSTYHPAPVSPGHSTAVVSLP--GSQQHLSANMFVALHSYSAHGPDELDLQKGEGVRVLGKCQDGWLRGVSLVTGRVGIFPNNYVIPIF----RKTSSFPDSRSPGLYTTWTLSTS---SVSSQGSISEGDPRQSRPFKSVFVPTAIVNPVRSTAGPGTLGQGSLRKGRSSMRKNG------------SLQRPLQSGIPTLVVGSLRRSP----TMVLRPQQFQFYQPQGIPSSP--SAVVVEMGSKPALTGEPALTCISRGSEAWIHSAASSLIMEDKEIPIKSEPLPKP------PASAPPSILVKPENSRNGIEKQVKTVRFQNYSPPPTKHYTSHPTSGKPEQPATLKASQPEAASLGPEMTVLFAHRSG------CHSGQQTDLRRKSALGKATTLVSTASGTQTVFPSK--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QGN1-1", "uniprot_id": "A0A8M9QGN1_DANRE", "id": "A0A8M9QGN1-1", "name": "", "aln": "MEDLAVMELLECPLCMEPLDVSAKVLPCQHTFCKSCLQQQETSHPDQLCCPECRAAVPGSVEELPTNPLLHRLLESLH------EWGPVSTPRDRSVR---YMSSPAQEDHCSSYTQDLPKQEQNTQRVQAQALYDFQGNAPGELTMKSGDIIYLRWRVDDNWYYGEGKDSRGLVPVNVLQVLSEQPQPLALCRALYDFNANNLDPEGSKECLTFFKGDSITLLKQVNENWVEGKLGDKVGIFPLQLTEPNPAAYELLEKHKRRDSVEAQPRSSVRVNADACIHRRLTGPSQKSSRPSNVNLLNSLNCPPLSLSQQPPHISSSAQPSYSKTPQLATFNRPRLRSSRRNLPKRHRTMNGESPPAITMALINPQASPMPSESKMSATQQLSISVCAALYSYTPYRSEELELRKGEMVGVYGKFSEGWLRGLSLKTGKVGILPTNYVTPVL----RTSARFLEQSKPAIPNSSAVSTKRHASHKPQAVVLALDRVNTDSPSATMPVTSSAGPGRAAQLGGKQGWSSVRRSFHATHRGLPHHGSYNSNSILSLQPPPQDLGQIYTFGRSPVLPKKRNGLFSNPMKAQHWAYETTSPSAGAYQPIINPGQKETTTTRQSILVKPDAYKNNAEKPVKSVRFLAHDTPQTAPKTPSTSTAGLSSSSQPGFSTLDHWNPSAILGRDGHTLVLKDTKTPPARKSTGQDHAAMDSLALNMKPVLINNQSGSSRCRVIKGYNAKTDAELTLTEGEMVLVQRPRADGRVLVTQEISGKTGLFQSSVLELLDKIL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:**::::*****:*:* ***:************.***: .:* .:* *****: * .:* **:* ** ***:.:: . *.. * ::: : .: :.*.: : : :*:** :::*: **:* ::.**:* *: ::*:*** ** :. * .*.. ::*:.: *** .******:*: .. * . .::****:*.* **::.:*:***.************: :.*** :* .*** * :: .:: * : : . . : .** . . : ..*. :: * ... : .** * : . * : :. : .. : *: .. . . :::.: * . .: *:** .: .**::*:. .:**:*:*** : * ** .:***:*:** **:.**:*.:** *:: *.:: * :. * : .: ::**. * ..*. . * :: . :.: *: * *:: *. * .*:*: : ::. *** * *. .* * :. .* : *.: : ..*. ::: *.* * . :: . : ... .*: : :: * .: *.. .:* * :. *. :: :*: ::: ..**::: :. :. . . .:* : * . :: .:.: .*: . ::* * .:. . :. : . .* ", "identical_positions": 194, "similar_positions": 266, "identity": "24.81%" }, { "cls_id": "homologset.agr.RGD:1308416", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZWH2-1", "uniprot_id": "D3ZWH2_RAT", "id": "D3ZWH2-1", "name": "Junctophilin", "aln": "MSSGGRFNFDDGGSYCGGWEDGKAHGHGVCTGPKGQGEYTGSWSHGFEVLGVYTWPSGNTYQGTWAQGKRHGIGLESKGKWVYKGEWTHGFKGRYGVRECTGNGAKYEGTWSNGLQDGYGTETYSDGGTYQGQWVGGMRQGYGVRQSVPYGMAAVIRSPLRTSINSLRSEHTNGAALHPDASPAVAGSPAVSRGGFVLVAHSDSEILKSKKKGLFRRSLLSGLKLRKSESKSSLASQRSKQSSFRSEAGMSTVSSTASDIHSTISLGEAEAELAVIEDDIDATTTETYVGEWKNDKRSGFGVSQRSDGLKYEGEWVSNRRHGYGCMTFPDGTKEEGKYKQNVLVSGKRKNLIPLRASKIREKVDRAVEAAERAATIAKQKAEIAASRTSHSRAKAEAALTAAQKAQEEARIARITAKEFSPSFQHRENGLEYQRPKHQMSCDDIEVLSTGTPLQQESPELYRKGTTPSDLTPDDSPLQSFPASPTATPPPAPASRNKMAHFSRQVSVDEERSGDIQMLLEGRGGDYARNSWGEEKAGASRGVRSGALRSGQPTEDFRTRGSGHKQPGNPKPRERRTESPTTFSWTSHHRAGNPCSGGPKLLQPDEEQLSNYKLEMKPLLRMDACPQDTHPQRRRHSRGAGGDRRSEDRGFGLQRLRSKSQNKENLRPASSAEPTVQKLESLRLGDRPEPRLLRWDLTFSPPQKSLPVALESDEETGDELKSSTGSAPILVVMVILLNIGVAILFINFFI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ET77-1", "uniprot_id": "JPH3_MOUSE", "id": "Q9ET77-1", "name": "Junctophilin-3", "aln": "MSSGGRFNFDDGGSYCGGWEDGKAHGHGVCTGPKGQGEYTGSWSHGFEVLGVYTWPSGNTYQGTWAQGKRHGIGLESKGKWVYKGEWTHGFKGRYGVRECTGNGAKYEGTWSNGLQDGYGTETYSDGGTYQGQWVGGMRQGYGVRQSVPYGMAAVIRSPLRTSINSLRSEHTNGAALHPDASPAVAGSPAVSRGGFVLVAHSDSEILKSKKKGLFRRSLLSGLKLRKSESKSSLASQRSKQSSFRSEAGMSTVSSTASDIHSTISLGEAEAELAVIEDDIDATTTETYVGEWKNDKRSGFGVSQRSDGLKYEGEWVSNRRHGYGCMTFPDGTKEEGKYKQNVLVSGKRKNLIPLRASKIREKVDRAVEAAERAATIAKQKAEIAASRTSHSRAKAEAALTAAQKAQEEARIARITAKEFSPSFQHRENGLEYQRPKHQMSCDDIEVLSTGTPLQQESPELYRKGTTPSDLTPDDSPLQSFPASPTSTPPPAPASRTKMAHFSRQVSVDEERSGDIQMLLEGRGGDYARNSWGEEKAGASRGIRSGALRSGQPTEDFRTRGSGHKQPGNPKPRERRTESPTTFSWTSHHRAGNPCSGGPKLLEPDEEQLSNYKLEMKPLLRMDACPQDTHPQRRRHSRGAGGDR-----GFGLQRLRSKSQNKENLRPASSAEPTVQKLESLRLGDRPEPRLLRWDLTFSPPQKSLPVALESDEETGDELKSSTGSAPILVVMVILLNIGVAILFINFFI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WXH2-1", "uniprot_id": "JPH3_HUMAN", "id": "Q8WXH2-1", "name": "Junctophilin-3", "aln": "MSSGGRFNFDDGGSYCGGWEDGKAHGHGVCTGPKGQGEYTGSWSHGFEVLGVYTWPSGNTYQGTWAQGKRHGIGLESKGKWVYKGEWTHGFKGRYGVRECAGNGAKYEGTWSNGLQDGYGTETYSDGGTYQGQWVGGMRQGYGVRQSVPYGMAAVIRSPLRTSINSLRSEHTNGTALHPDASPAVAGSPAVSRGGFVLVAHSDSEILKSKKKGLFRRSLLSGLKLRKSESKSSLASQRSKQSSFRSEAGMSTVSSTASDIHSTISLGEAEAELAVIEDDIDATTTETYVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKYKQNILVGGKRKNLIPLRASKIREKVDRAVEAAERAATIAKQKAEIAASRTSHSRAKAEAALTAAQKAQEEARIARITAKEFSPSFQHRENGLEYQRPKRQTSCDDIEVLSTGTPLQQESPELYRKGTTPSDLTPDDSPLQSFPTSPAATPPPAPAARNKVAHFSRQVSVDEERGGDIQMLLEGRAGDCARSSWGEEQAGGSRGVRSGALRGGLLVDDFRTRGSGRKQPGNPKPRERRTESPPVFTWTSHHRASNHSPGGSRLLELQEEKLSNYRMEMKPLLRMETHPQKRRYSKGGACRGLGDDHRPEDRGFGVQRLRSKAQNKENFRPASSAEPAVQKLASLRLGG-AEPRLLRWDLTFSPPQKSLPVALESDEENGDELKSSTGSAPILVVMVILLNIGVAILFINFFI", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****************************************************************************************************:*************************************************************************:********************************************************************************************************************************************.*************************:**.*******************************************************************************************:* ******************************************:**::*******:*.*:*************.**********.** **.*****:**.***:******.* .:********:****************..*:*******.* ..**.:**: :**:****::********:: **. : .: .** *.*: ***:******:*****:********:**** *****. .***************************.**********************************", "identical_positions": 678, "similar_positions": 51, "identity": "90.52%" }, { "cls_id": "homologset.agr.RGD:1308417", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4ACD0-1", "uniprot_id": "D4ACD0_RAT", "id": "D4ACD0-1", "name": "Homeobox protein Hox-D13", "aln": "MSRSGTWDMDGLRADGGAAGAAPASSSSS----VAAPGQCRGFLSAPVFAGTHSGRAAAAAAAAAAAAAAASSFAYPGTSERTGSSSSSSSSAVIATRPEAPVAKECPAPAAAATAAAPPGAPALGYGYHFGNGYYSCRMSHGVGLQQNALKSSPHASLGGFPVEKYMDVSGLASSSVPTNEVPARAKEVSFYQGYTSPYQHVPGYIDM--VSTFGSGEPRHEAYISMEGYQSWTLANGWNSQVYCAKDQPQGSHFWKSSFPGDVALNQPDMCVYRRGRKKRVPYTKLQLKELENEYAINKFINKDKRRRISAATNLSERQVTIWFQNRRVKDKKIVSKLKDTVS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70217-1", "uniprot_id": "HXD13_MOUSE", "id": "P70217-1", "name": "Homeobox protein Hox-D13", "aln": "MSRSGTWDMDGLRADGGAAGAAPASSSSS----VAAPGQCRGFLSAPVFAGTHSGRAAAAAAAAAAAAAAASSFAYPGTSERTGSSSSSSSSAVIATRPEAPVAKECPAPAAAATAAAPPGAPALGYGYHFGNGYYSCRMSHGVGLQQNALKSSPHASLGGFPVEKYMDVSGLASSSVPTNEVPARAKEVSFYQGYTSPYQHVPGYIDM--VSTFGSGEPRHEAYISMEGYQSWTLANGWNSQVYCAKDQPQGSHFWKSSFPGDVALNQPDMCVYRRGRKKRVPYTKLQLKELENEYAINKFINKDKRRRISAATNLSERQVTIWFQNRRVKDKKIVSKLKDTVS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P35453-1", "uniprot_id": "HXD13_HUMAN", "id": "P35453-1", "name": "Homeobox protein Hox-D13", "aln": "MSRAGSWDMDGLRADGGGAGGAPASSSSSSVAAAAASGQCRGFLSAPVFAGTHSGRAAAAAAAAAAAAAAASGFAYPGTSERTGSSSSSSSSAVVAARPEAPPAKECPAPTPAAAAAAPPSAPALGYGYHFGNGYYSCRMSHGVGLQQNALKSSPHASLGGFPVEKYMDVSGLASSSVPANEVPARAKEVSFYQGYTSPYQHVPGYIDM--VSTFGSGEPRHEAYISMEGYQSWTLANGWNSQVYCTKDQPQGSHFWKSSFPGDVALNQPDMCVYRRGRKKRVPYTKLQLKELENEYAINKFINKDKRRRISAATNLSERQVTIWFQNRRVKDKKIVSKLKDTVS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q90472-1", "uniprot_id": "HXDDA_DANRE", "id": "Q90472-1", "name": "Homeobox protein Hox-D13a", "aln": "-------------MDGGGLDEEFINVYPS-------------------AFGTHSSRCTSGAPVLSAVDRPTS------------------------------VCNESISPYFSFPSNIGSGS------FTFG-----CHLENSYKVPQNAVFPPGVAKQNGQ----------FANKPVDHGEASSWLKEFAFYQGCARSYPRIPAFIDLPVVQRAMMGDLRHETCLTMEGHQHWDWSNNCSSQLYCFQDQTRSPHIWKPSLTEEAAAAS----FCQRGRKKRVPYTKFQLKELEREYNTTKFITKENRRRIASSTNLSERQVTIWFQNRRVKDKKRPDVCIKC--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***. . . .* ****.*.::.*.. :*. .:* .:*. :* : .: ..: : ** *::.:. : ***: .. *. .* :*...* .*..: **.:**** : .* ::*.:**: *. *: ***: ::***:* * :*. .**:** :**.:..*:**.*:. :.* . . :***********:******.** .***.*::****:::********************* . . ", "identical_positions": 105, "similar_positions": 89, "identity": "30.43%" }, { "cls_id": "homologset.agr.RGD:1308418", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q7TN29-1", "uniprot_id": "SMAP2_MOUSE", "id": "Q7TN29-1", "name": "Stromal membrane-associated protein 2", "aln": "-----MTGKSVKDVDRYQAVLANLLLEEDNKFCADCQSKG-PRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQWTQEQIQCMQEMGN-GKANRLYEAYLPETFRRPQIDP-----------AVEGFIRDKYEKKKYMD--------------RSLDINVLRKEK---------------------DDKWKRGNEPAPEKKMEPVVFEKVKMPQK-----KEDAQLPRKSSPKSAAPVMDLLGLDAPVACSIANSKTSNALEKDLDLLASVPSPSS-VSRKAVGSMPTAGSAGSVPENLN----LFPEPGSK----SEETGKKQLSKDSILSLYGSQTPQMPAQAMF-----MAPAQMAYPTAYPSFPG--VTPPNSIMGG---MVPPPVGMVAQPGASGMLTPMAMPAGYMGGMQASMMGVPNGMMTTQQAG-----YMASMAAMPQTVYGVQPAQQLQWNLTQMTQQMAG---MNFYG-ANGMMNYGQSMGGGNGQAAN--------QTLSPQMWK--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8J8XM71-1", "uniprot_id": "A0A8J8XM71_RAT", "id": "A0A8J8XM71-1", "name": "", "aln": "-----MTGKSVKDVDRYQAVLANLLLEEDNKFCADCQSKG-PRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQWTQEQIQCMQEMGN-GKANRLYEAYLPETFRRPQIDPFFDSSLISVCRAVEGFIRDKYEKKKYMD--------------RSLDINVLRKEK---------------------DDKWKRGSEPAPEKKMEPVVFEKVKMPQK-----KEDAQLPRKSSPKSAAPVMDLLGLDAPVACSIANSKTSNALEKDLDLLASVPSPSS-VSRKAVGSMPTAGSAGSVPENLN----LFPEPGSK----SEETGKKQLSKDSILSLYGSQTPQMPAQAMF-----MAPAQMAYPTAYPSFPG--VTPPNSIMGS---MMPPPVGMVAHPGASGMVTPMAMPAGYMGGMQASMAGVPSGMMTTQQAG-----YMASMAAMPQTVYGVQPAQQLQWNLTQMTQQMAG---MNFYG-ANGMMSYGQSMGGGNGQAAN--------QTLSPQMWK--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8WU79-1", "uniprot_id": "SMAP2_HUMAN", "id": "Q8WU79-1", "name": "Stromal membrane-associated protein 2", "aln": "-----MTGKSVKDVDRYQAVLANLLLEEDNKFCADCQSKG-PRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQWTQEQIQCMQEMGN-GKANRLYEAYLPETFRRPQIDP-----------AVEGFIRDKYEKKKYMD--------------RSLDINAFRKEK---------------------DDKWKRGSEPVPEKKLEPVVFEKVKMPQK-----KEDPQLPRKSSPKSTAPVMDLLGLDAPVACSIANSKTSNTLEKDLDLLASVPSPSSSGSRKVVGSMPTAGSAGSVPENLN----LFPEPGSK----SEEIGKKQLSKDSILSLYGSQTPQMPTQAMF-----MAPAQMAYPTAYPSFPG--VTPPNSIMGS---MMPPPVGMVAQPGASGMVAPMAMPAGYMGGMQASMMGVPNGMMTTQQAG-----YMAGMAAMPQTVYGVQPAQQLQWNLTQMTQQMAG---MNFYG-ANGMMNYGQSMSGGNGQAAN--------QTLSPQMWK--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1Z7K6-1", "uniprot_id": "A1Z7K6_DROME", "id": "A1Z7K6-1", "name": "Arf-GAP domain-containing protein", "aln": "MSSSNAGQRTKLIQEKCQTLLTQMLRDEDNKYCVDCDAKG-PRWASWNLGMFLCIRCAGIHRNLGVHISRVKSVNLDTWTPEQVISLQQMGN-SRARAVYEAQLPDGFRRPQTDT-----------ALENFIRAKYEHKKYLAREWVPPSPPKVDWAKEIDEELERQKRKKKSTQAQATLGLAGVAGGSGDKRLSGSSASALKNTPLPAPLPKPKPNQVGGCSPKTTQRVQLNSSGVSSAGESDLLGLSSPTKPIVATNASQDLQNESFTSFLSAESIAGQPDKPIGSNGDAANLMGSKPNSLAQEEQDFFNQGSLGAGGNEKDQSGKMSKDSILALYGSAPATHNPQMNFGGFTGMAPGGYMHQQQQQQIPHQFMTPPNSVSMYNSPVMAAPNAFSNAAISSATAMSMGGSHGFTGAQFPSTGGSPYAAAGQAAATNLMQTNQSILSGMPLFGAVPQQQQQHQQQLQQQHHPQLGGLSMNLMQPLPSGLNIGQPPQGAGGFAATGPTTSSVPSNLNQQFGNLNIGNVWQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40529-1", "uniprot_id": "AGE2_YEAST", "id": "P40529-1", "name": "ADP-ribosylation factor GTPase-activating protein effector protein 2", "aln": "----------MSTSVPVKKALSALLRDPGNSHCADCKAQLHPRWASWSLGVFICIKCAGIHRSLGTHISKVKSVDLDTWKEEHLVKLIQFKNNLRANSYYEATLADELKQRKITDTS---------SLQNFIKNKYEYKKWIG-------------------DLSSIEG------------------------LNDSTEPVLHKPSANHSLPASNARLD---------QSSNSLQKTQTQPPSHLLSTSR------SNTSLLNLQVSSLSKTTSNTSVTSSATSIGAANTKTGNRVG-------------------------EFGQRNDLKKSILSLYSKPSAQTQSQNSF-------------------------------------------------FTSTTPQPCNTPSPFVNTGITATNNNSMNSNSSSNIS--------------------LDDNELFKNVWS-------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *: :* : .*..*.**.:: ******.:*:*:**:******.**.***:****:** *. *:: : :: * :*. *** *.: ::: : :::.**: *** **:: : : . .. .. .: : : : . . .: .**. . :.. : ..: * * :. .. :.. * : . : *.***:**.. .. .* * :* . . : . .: . . :: :: . ", "identical_positions": 62, "similar_positions": 98, "identity": "11.7%" }, { "cls_id": "homologset.agr.RGD:1308419", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M9J5-1", "uniprot_id": "A0ABK0M9J5_RAT", "id": "A0ABK0M9J5-1", "name": "", "aln": "MESAPAAPDPAASEPGSSGSEAAAGSRETPLTQDAGRKSEAPGAGRRQSYASSSRGISVTKKTHTSQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQ-QQRDHQQQPGEAEPLTPTYNISANGLTELHDDLSTYMDGHTPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGKYASPDVFKSLGCEDF--ISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHR----EDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLYKELFTSEFEPAMQIDG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P51448-1", "uniprot_id": "RORA_MOUSE", "id": "P51448-1", "name": "Nuclear receptor ROR-alpha", "aln": "MESAPAAPDPAASEPGSSGSEAAAGSRETPLTQDTGRKSEAPGAGRRQSYASSSRGISVTKKTHTSQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQ-QQRDHQQQPGEAEPLTPTYNISANGLTELHDDLSTYMDGHTPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGKYASPDVFKSLGCEDF--ISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHR----EDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLYKELFTSEFEPAMQIDG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P35398-2", "uniprot_id": "RORA_HUMAN", "id": "P35398-2", "name": "Nuclear receptor ROR-alpha", "aln": "MESAPAAPDPAASEPGSSGADAAAGSRETPLNQESARKSEPPAPVRRQSYSSTSRGISVTKKTHTSQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQ-QQRDHQQQPGEAEPLTPTYNISANGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGKYASPDVFKSLGCEDF--ISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHR----EDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLYKELFTSEFEPAMQIDG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QLY4-1", "uniprot_id": "RORAA_DANRE", "id": "F1QLY4-1", "name": "Nuclear receptor ROR-alpha A", "aln": "-----------------------------------------------MMYFVIS--------AMKAQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNAAYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRLQQ-QQRDHQQQPGEAEPLTPTYGLSTNGLTELHDDLSGYMNGHTPDGTKPDSGVSSFYLDIQPSPDQSGLDINGIKPEPICDFTPGSGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHMETCQYLREELQQMTWQAFLQEEVENYQSKPREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFVRMCRAFDPQNNTVYFDGKYAGPDVFKSLGCDDL--ISSVFEFGKNLCSMHLSEDEIALFSAFVLMSADRSWLQEKVKVEKLQQKIQLALQHVLQKNHR----EDGILTKLICKVSTLRALCSRHTEKLTAFKAIYPDIVRAHFPPLYKELFGSDFEQSMPVDG", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P31396-1", "uniprot_id": "HR3_DROME", "id": "P31396-1", "name": "Probable nuclear hormone receptor HR3", "aln": "----------------------MYTQRMFDMWSSVTSKLEAHANNLGQSNVQSPAGQNNSSGSIKAQIEIIPCKVCGDKSSGVHYGVITCEGCKGFFRRSQSSVVNYQCPRNKQCVVDRVNRNRCQYCRLQKCLKLGMSRDAVKFGRMSKKQREKVEDEVRFHRAQMRAQSDAAPDSSVYDTQTPS---SSDQLH--HNNYNSYSGGYSNNEVGYG---SPYGYSASVTPQQT------MQYDISADYVDSTTYEPRSTIIDPEFISHADGDINDVLIKTLAEAHANTNTKL-EAVHDMFRKQPDVSRILYYKNLGQEELWLDCAEKLTQMIQNIIEFAKLIPGFMRLSQDDQILLLKTGSFELAIVRMSRLLDLSQNAVLYGDVMLPQEAFYTSDSEEMRLVSRIFQTAKSIAELKLTETELALYQSLVLLWPERNGVRGNTEIQRLFNLSMNAIRQELETNHAPLKGDVTVLDTLLNNIPNFRDISILHMESLSKFKLQHPNVV---FPALYKELFSIDSQQDLT---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : .:********:*******:******************.* . *.***:*:*::**..*****:******* :*****************:.: **: ** * * * :.. :. **: *:: * *:: . * .*:: : . *.: . . :*:*: :: : .*:. .: : * .:: : * . .. : * :.::::* :* * * :::: : ..: *:. :* :* ** *:*: ** ::**** * ***.*.*:***:***:**:*:.::**.* :* .:*:* :.. :.* : ..::: :* :*: .*.:..::*:* *:**:.::**: .:*. :: :.::::* : *::: *:.** : :* .*: ::..:* :. * *.* ** :*::* **.****** : : : ", "identical_positions": 165, "similar_positions": 163, "identity": "31.13%" }, { "cls_id": "homologset.agr.RGD:1308420", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZXW7-1", "uniprot_id": "A0A8I5ZXW7_RAT", "id": "A0A8I5ZXW7-1", "name": "", "aln": "-----------MPYSRISLRNSLDGGFLLSDDSSLCPVDLKLPSTPIGPLKTMLLVDREMANP-EVVVSSCSSHQDESPCTFYPSSSQSEQLLLEDQMRRKLKFFFMNPCEKFWARGRKPWKLAIQILKIAMVTIQLVLFGLSNQMVVAFKEENTIAFKHLFLKGYMDRM--------DDTYAVYTQNDVYDQIIFAVTRYLQLRNISVGNHAYENKGTKQSAMAVCQHFYRQGTICPGNDTFDIDPEVETDCFLIEPEEAFHMGTPGENKLNLTLDFHRLLTVELQFKLKAINLQTVR-HQELPDCYDFTLTITFDNKAHSGRIKISLDNDISIRECK-DWHVSGSIQKNTHYMMIFDAFVILTCLSSLVLCARSVIRGLQLQQEFVNFFLLHYKKEVSASDQMEFINGWYIMIIVSDILTIVGSILKMEIQAK--SLTSYDVCSILLGTSTMLVWLGVIRYLGFFAKYN----------LLILTLQAALPNVIRFCCCAAMIYLGYCFCGWIVLGPYHEKFRSLNKVSECLFSLINGDDMFSTFAKMQQKSYLVWLFSRVYLYSFISLFIYMILSLFIALITDTYETIKHYQQDGFPETELRKFIAECKDLPNSG---KYRLEDDPPGS------LFCCCKK----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R4F0-1", "uniprot_id": "MCLN3_MOUSE", "id": "Q8R4F0-1", "name": "Mucolipin-3", "aln": "-----------------------------------------------------------MANP-EVLVSSCRARQDESPCTFHPSSSPSEQLLLEDQMRRKLKFFFMNPCEKFWARGRKPWKLAIQILKIAMVTIQLVLFGLSNQMVVAFKEENTIAFKHLFLKGYMDRM--------DDTYAVYTQSEVYDQIIFAVTQYLQLQNISVGNHAYENKGTKQSAMAICQHFYRQGTICPGNDTFDIDPEVETECFLVEPDEASHLGTPGENKLNLSLDFHRLLTVELQFKLKAINLQTVR-HQELPDCYDFTLTITFDNKAHSGRIKISLDNDISIKECK-DWHVSGSIQKNTHYMMIFDAFVILTCLASLVLCARSVIRGLQLQQEFVNFFLLHYKKEVSASDQMEFINGWYIMIIISDILTIVGSVLKMEIQAK--SLTSYDVCSILLGTSTMLVWLGVIRYLGFFAKYN----------LLILTLQAALPNVMRFCCCAAMIYLGYCFCGWIVLGPYHEKFRSLNRVSECLFSLINGDDMFSTFAKMQQKSYLVWLFSRVYLYSFISLFIYMILSLFIALITDTYETIKHYQQDGFPETELRKFIAECKDLPNSG---KYRLEDDPPGS------LLCCCKK----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TDD5-1", "uniprot_id": "MCLN3_HUMAN", "id": "Q8TDD5-1", "name": "Mucolipin-3", "aln": "-----------------------------------------------------------MADP-EVVVSSCSSHEEENRCNFNQQTSPSEELLLEDQMRRKLKFFFMNPCEKFWARGRKPWKLAIQILKIAMVTIQLVLFGLSNQMVVAFKEENTIAFKHLFLKGYMDRM--------DDTYAVYTQSDVYDQLIFAVNQYLQLYNVSVGNHAYENKGTKQSAMAICQHFYKRGNIYPGNDTFDIDPEIETECFFVEPDEPFHIGTPAENKLNLTLDFHRLLTVELQFKLKAINLQTVR-HQELPDCYDFTLTITFDNKAHSGRIKISLDNDISIRECK-DWHVSGSIQKNTHYMMIFDAFVILTCLVSLILCIRSVIRGLQLQQEFVNFFLLHYKKEVSVSDQMEFVNGWYIMIIISDILTIIGSILKMEIQAK--SLTSYDVCSILLGTSTMLVWLGVIRYLGFFAKYN----------LLILTLQAALPNVIRFCCCAAMIYLGYCFCGWIVLGPYHDKFRSLNMVSECLFSLINGDDMFATFAKMQQKSYLVWLFSRIYLYSFISLFIYMILSLFIALITDTYETIKQYQQDGFPETELRTFISECKDLPNSG---KYRLEDDPPVS------LFCCCKK----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PLH2-1", "uniprot_id": "A0A8M9PLH2_DANRE", "id": "A0A8M9PLH2-1", "name": "", "aln": "-----------------------------------------------------------MDDSREDYLCINDPNGNWSECEAHVDP-------ALEAFRRKLKYFFMNPCDKYKARQRKPWKLFLQIVKIAVVTVQLVSFGLSNQMVVQFKEENLLTFRHLFLKNYSESN--------TNTYAIYTQLDVYTHITHIVQQFLMLPSITVGNHEYEQEGDVYTPLCICQQFYHNGSISPANETFDIDSRVDQECSLIYPQDPFT-----ESPLNFTLHFERLLSVTVNFTLKAINLETVE-YHELPDCYVFNIMIQFDNKAHSGRILVDLDNEVHIYECS-DWSMTGASARNMYMMVLFDAVVILILSTSLLLCIRSVKAGVLLQKEYSEFSLRRYRKCVSLSERLEFINGWYLLIIVSDVLTISGSVLKIVIQLK--AVASYDLCSILLGTGTMLVWIGVLRYMGYLKKYNSMLCVCCVVQILIITLRVALPNVIRFTCCAAMIYLGYCFCGWIVLGPYHTKFRTLNTVSESLFSLINGDDMFATFKNMQQKSFVVWLFSRLYLYTFVSLFIYMVLSLFITLITDTYDTIKHQQLDGEPVSDLQAFVLQCKDLPDSG---EFSVEKTNSISSTGGGKLMCCCSHRSSDSDEDTHFSECSS------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9P7U6-1", "uniprot_id": "A0A8M9P7U6_DANRE", "id": "A0A8M9P7U6-1", "name": "", "aln": "-----------------------------------------------------------MSDR--------ASHTHESATLLDPEC--------VESLRRKLKYFFMSPCQKYSTRGRIPWKMMLQILKIVIITVQLVSFGLSNEMMVTFKEENLIAFKHFFLKNYKDS---------NKHYALYTKHEVHDHILYTIRRYLQLQNLTIGNQALEMIDGLATPLSLCQQLYRHARVVPSNETFEIDPHVETECVSVYPLSPITTDS-LENSLNLTLDFQRLLAVNIYLKIKAINIQTVR-HQELPDCYDFSINIMFDNRAHSGQIKISLSSGVQINVCK-DWNISGSTDSHFALIVVFDCLIICFCLLSLILCTRSVHTGFLLQTEYRRFMSSQHSKSVSWSERLEFINGWYILIIISDALTIAGSILKICIQSK--ELTSYDVCSILLGTATMLVWIGVMRYLSFFQKYY----------ILILTLKAALPNVIRFSICAVMIYLSYCFCGWIVLGPHHENFRTFSRVAGCLFSMINGDEIYSTFTKLREYSTLVWLFSRLYVYSFIPVFTYMVLSVFIALITDTYETIRHYQKHGAPLSELQAFIADCRDPRNYD---KNTTNEDEESS------SFCCLCAPCVFCT----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VW35-1", "uniprot_id": "Q9VW35_DROME", "id": "Q9VW35-1", "name": "", "aln": "MQSYGPGAQTAPAVKRRTDSYEAAQQQQQSPESDEEYVNTRILRRQVQLQSTPVAPVVPMPISAGSGTAPPSVDGREEQPEFPGSSAAS---YQEERMRRKLQFFFMNPIEKWQAKRKFPYKFVVQIVKIFLVTMQLCLFAHSRYNHINYTGDNRFAFSHLFLRGWDSSREVESYPPAVGPFALYLKSEFFDTVQYAVNGYANVS-RSIGPYDYPTPNNTMPPLKLCLQNYREGTIFGFNESYIFDPHIDEVCERLPPNVTTIGVENYLRQRDVEVNFASLVSAQLTFKIKTVNFKANGGPLSAPDCFRFDISITFNNRDHDGQMLLSLDAEATRLKCHGATDFISDANFDSMLRSVLNIFVLLTCALSFALCTRALWRAYLLRCTTVNFFRSQFGKELSFDGRLEFVNFWYIMIIFNDVLLIIGSALKEQIEGRYLVVDQWDTCSLFLGIGNLLVWFGVLRYLGFFKTYN----------VVILTLKKAAPKILRFLIAALLIYAGFVFCGWLILGPYHMKFRSLATTSECLFALINGDDMFATFATLSSKATWLWWFCQIYLYSFISLYIYVVLSLFIAVIMDAYDTIKAYYKDGFPTTDLKAFVGTRTAEDISSGVFMTDLDDFDQTSFLDVVKSICCCGRCGRHQEPAQPNSGYTSLSSIMK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . . : :****::***.* :*: :: : *:*: :**:** ::*:** *. *. : :. :* ::* *:**:.: . :*:* : :.. : . : : : ::* . ..: :* : *:.. : *::: :*..:: * : * . :. :.* *::. : :.:*::*::: . ***: * : * *:*: *.*:: :.*. * . . . ::: .:: *: ** *:: . *: .* :. * :* . ::**:* **::**..* * * ** ** *: : : .:* **::** ..:***:**:**:.:: .* ::*:**: * *:::** .* :** .: ****::***:* :**:: .: .**::****::::** .: . : :* *.::*:*:*:.:: *::**:**::* *:*:**: .* * ::*: *: . :. * :** ", "identical_positions": 136, "similar_positions": 192, "identity": "20.42%" }, { "cls_id": "homologset.agr.RGD:1308421", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AY12-1", "uniprot_id": "NB5R2_RAT", "id": "Q6AY12-1", "name": "NADH-cytochrome b5 reductase 2", "aln": "--------------------------------------------------MSVKKKDLITLQDPEAK-----YPLPLIEKEQINHNTRRFRFGLPSPDHVLGLPVGNYVHLLAQINNELVIRAYTPVSSD-DDQGFVDLIIKIYFKNVHPKYPEGGKMTQYLENMKIGDTILFRGPTGRLFYNEPGTLLIKTDKTSEPEKKLVHHLGMIAGGTGITPMLQLIRHITKDT-SDGTRMSLLFANQTEEDILLRKELEEVATTHQNQFSLWYTLDR--------PPSG------WEYSSGFITADMIKEHLPPPGEA-TLILVCGPPPLIQEAAHPSLEQ-------LGYTKDMIFTY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3KNK3-1", "uniprot_id": "NB5R2_MOUSE", "id": "Q3KNK3-1", "name": "NADH-cytochrome b5 reductase 2", "aln": "--------------------------------------------------MSVKKKDLITLQDPEAK-----YPLPLIEKEQISHNTRRFRFGLPSPDHVLGLPVGNYVHLLAQINNELVIRAYTPVSSD-DDQGFVDLIIKIYFKNVHPKYPEGGKMTQYLENMKIGDTILFRGPTGRLFYNEPGTLLIKANKTSEPEKKLVHHLGMIAGGTGITPMLQLIRHITKDT-SDETRMSLLFANQTEEDILLRKELEEVATTHHKQFNLWYTLDR--------PPSD------WKYSSGFVSADMIKEHLPPPGED-TLILVCGPPPLIQAAAHPSLEQ-------LSYTKDMIFIY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6BCY4-1", "uniprot_id": "NB5R2_HUMAN", "id": "Q6BCY4-1", "name": "NADH-cytochrome b5 reductase 2", "aln": "--------------------------------------------------MNSRRREPITLQDPEAK-----YPLPLIEKEKISHNTRRFRFGLPSPDHVLGLPVGNYVQLLAKIDNELVVRAYTPVSSD-DDRGFVDLIIKIYFKNVHPQYPEGGKMTQYLENMKIGETIFFRGPRGRLFYHGPGNLGIRPDQTSEPKKTLADHLGMIAGGTGITPMLQLIRHITKDP-SDRTRMSLIFANQTEEDILVRKELEEIARTHPDQFNLWYTLDR--------PPIG------WKYSSGFVTADMIKEHLPPPAKS-TLILVCGPPPLIQTAAHPNLEK-------LGYTQDMIFTY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q0P487-1", "uniprot_id": "NB5R2_DANRE", "id": "Q0P487-1", "name": "NADH-cytochrome b5 reductase 2", "aln": "-----------MDILTAPVLIGVSIVVITVLY------LFLKPAGSNSTPPKPQNKIPKALQDPSVK-----YPLPLIEKEEINHDTKRFRFGLPSSSHVLGLPIGQHIYLSAKVNGSLVVRAYTPVSSD-QDQGYVDLVVKVYYKNTHPSYPDGGKMSQYLDNMKIGDTIDFRGPNGLLVYNGKGKFAIRPDKKSEAEVRKFKHVAMIAGGTGITPMLQLIRSITADS-FDETVCSLIFANQTEKDILLRNELDEVHRNHPSKLKLWYTLDR--------PSEG------WKYSEGFVNAAMMKDHLPPADSD-VLVVMCGPPAMIEKACLPNLLK-------LGYKKENIFAY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "X2JGK6-1", "uniprot_id": "X2JGK6_DROME", "id": "X2JGK6-1", "name": "NADH-cytochrome b5 reductase", "aln": "-----------MARIVESNFVPLAVGVVAVLAGALIVHYLLNKKSTKPRREPNRTARLRTLVDPNDK-----YLLPLIEKENLSHDTRRFRFGLPSKQHVLGLPVGQHIHLIATIDNELIIRPYTPISSD-EDVGYVDLVVKVYFKDSHPKFPAGGKMTQHLEQLELGDKISFRGPSGRLQYLGNGTFSIKKLRKDPPKHVTAKRVNMIAGGTGITPMLQLAREVLKRSDKDKTELALLFANQSEKDILLRAELDELAQKHPDQFKIWYTVDKANEAIKRMPRMGNARFVAWSYNTGHVNDDMMQQHLYPPGED-TLCLLCGPPPMVNYTCIPGLER-------LGHRAEQRFSY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38626-1", "uniprot_id": "NCB5R_YEAST", "id": "P38626-1", "name": "NADH-cytochrome b5 reductase 1", "aln": "-----------MAIDAQKLVVVIVIVVVPLLF------------------KFIIGPKTKPVLDPKRND---FQSFPLVEKTILTHNTSMYKFGLPHADDVLGLPIGQHIVIKANINGKDITRSYTPTSLDGDTKGNFELLVKS--------YPTG-NVSKMIGELKIGDSIQIKGPRGNYHY----------------ERNCRSHLGMIAGGTGIAPMYQIMKAIAMDP-HDTTKVSLVFGNVHEEDILLKKELEALVAMKPSQFKIVYYLDS--------PDRED-----WTGGVGYITKDVIKEHLPAATMDNVQILICGPPAMVASVRRSTVDLGFRRSKPLSKMEDQVFVF", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q12746-1", "uniprot_id": "PGA3_YEAST", "id": "Q12746-1", "name": "Plasma membrane-associated coenzyme Q6 reductase PGA3", "aln": "MSKEDIEGTNILDEPVHGIYIPAALFVVGVAITTYMSGELKILWSLPILFMIIFVRAYSAYKRRRSLYPDRWTSLELEDQTIISKNTALYRFKLKTRLESLDIPAGHHVAVRVPIDGKQEVRYYNPISSK-LESGYLDLVVKAY---------VDGKVSKYFAGLNSGDTVDFKGPIGTLNY----------------EPNSSKHLGIVAGGSGITPVLQILNEIITVP-EDLTKVSLLYANETENDILLKDELDEMAEKYP-HFQVHYVVHY--------PSDR------WTGDVGYITKDQMNRYLPEYSED-NRLLICGPDGMNNLALQYAKELGWKVNSTRSSGDDQVFVF", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q04516-1", "uniprot_id": "AIM33_YEAST", "id": "Q04516-1", "name": "Uncharacterized oxidoreductase AIM33", "aln": "MSIVETCISFVSTNPFYPFCTGLLLNCVVTPLYFWKTQNGRIVVVSLLQFVVLYATAFISIGTDKSLYRNKWVALPLSKKTRISRNTSLYCFKLKYPFERLHIPMGYHLAVRVTINGERLVRYYTPVNVP-NTEGHLELVVKTY---------KHGVVSKYFDKLKIRQYVEFKGPLGELEY----------------DQDTATELGIIAGGSGITPVLQVLQEIIPSP-EDLTHISLIYANETEDDILMKSQLDHMAKEYP-HFKVHYVIHK--------PNGK------WNGDVGYVTLEEMKRYLPKQAED-HRLLICGPPKMNEMVLNYAKELGWSNGFHKGNGTDKVFVF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : * .: :.::* : * * . * :* * :: : . ::.. * *.* . * .:*::* ::: : :: : : ::** * * . .: ::***:**:*: *: . : . * * :*::.* *.***:: :*: : ::.: * :. * * . *.:. :: :* ::*** : . . : * :", "identical_positions": 42, "similar_positions": 77, "identity": "11.83%" }, { "cls_id": "homologset.agr.RGD:1308422", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8WXI7-1", "uniprot_id": "MUC16_HUMAN", "id": "Q8WXI7-1", "name": "Mucin-16", "aln": "MLKPSGLPGSSSPTRSLMTGSRSTKATPEMDSGLTGATLSPKTSTGAIVVTEHTLPFTSPDKTLASPTSSVVGRTTQSLGVMSSALPESTSRGMTHSEQRTSPSLSPQVNGTPSRNYPATSMVSGLSSPRTRTSSTEGNFTKEASTYTLTVETTSGPVTEKYTVPTETSTTEGDSTETPWDTRYIPVKITSPMKTFADSTASKENAPVSMTPAETTVTDSHTPGRTNPSFGTLYSSFLDLSPKGTPNSRGETSLELILSTTGYPFSSPEPGSAGHSRISTSAPLSSSASVLDNKISETSIFSGQSLTSPLSPGVPEARASTMPNSAIPFSMTLSNAETSAERVRSTISSLGTPSISTKQTAETILTFHAFAETMDIPSTHIAKTLASEWLGSPGTLGGTSTSALTTTSPSTTLVSEETNTHHSTSGKETEGTLNTSMTPLETSAPGEESEMTATLVPTLGFTTLDSKIRSPSQVSSSHPTRELRTTGSTSGRQSSSTAAHGSSDILRATTSSTSKASSWTSESTAQQFSEPQHTQWVETSPSMKTERPPASTSVAAPITTSVPSVVSGFTTLKTSSTKGIWLEETSADTLIGESTAGPTTHQFAVPTGISMTGGSSTRGSQGTTHLLTRATASSETSADLTLATNGVPVSVSPAVSKTAAGSSPPGGTKPSYTMVSSVIPETSSLQSSAFREGTSLGLTPLNTRHPFSSPEPDSAGHTKISTSIPLLSSASVLEDKVSATSTFSHHKATSSITTGTPEISTKTKPSSAVLSSMTLSNAATSPERVRNATSPLTHPSPSGEETAGSVLTLSTSAETTDSPNIHPTGTLTSESSESPSTLSLPSVSGVKTTFSSSTPSTHLFTSGEETEETSNPSVSQPETSVSRVRTTLASTSVPTPVFPTMDTWPTRSAQFSSSHLVSELRATSSTSVTNSTGSALPKISHLTGTATMSQTNRDTFNDSAAPQSTTWPETSPRFKTGLPSATTTVSTSATSLSATVMVSKFTSPATSSMEATSIREPSTTILTTETTNGPGSMAVASTNIPIGKGYITEGRLDTSHLPIGTTASSETSMDFTMAKESVSMSVSPSQSMDAAGSSTPGRTSQFVDTFSDDVYHLTSREITIPRDGTSSALTPQMTATHPPSPDPGSARSTWLGILSSSPSSPTPKVTMSSTFSTQRVTTSMIMDTVETSRWNMPNLPSTTSLTPSNIPTSGAIGKSTLVPLDTPSPATSLEASEGGLPTLSTYPESTNTPSIHLGAHASSESPSTIKLTMASVVKPGSYTPLTFPSIETHIHVSTARMAYSSGSSPEMTAPGETNTGSTWDPTTYITTTDPKDTSSAQVSTPHSVRTLRTTENHPKTESATPAAYSGSPKISSSPNLTSPATKAWTITDTTEHSTQLHYTKLAEKSSGFETQSAPGPVSVVIPTSPTIGSSTLELTSDVPGEPLVLAPSEQTTITLPMATWLSTSLTEEMASTDLDISSPSSPMSTFAIFPPMSTPSHELSKSEADTSAIRNTDSTTLDQHLGIRSLGRTGDLTTVPITPLTTTWTSVIEHSTQAQDTLSATMSPTHVTQSLKDQTSIPASASPSHLTEVYPELGTQGRSSSEATTFWKPSTDTLSREIETGPTNIQSTPPMDNTTTGSSSSGVTLGIAHLPIGTSSPAETSTNMALERRSSTATVSMAGTMGLLVTSAPGRSISQSLGRVSSVLSESTTEGVTDSSKGSSPRLNTQGNTALSSSLEPSYAEGSQMSTSIPLTSSPTTPDVEFIGGSTFWTKEVTTVMTSDISKSSARTESSSATLMSTALGSTENTGKEKLRTASMDLPSPTPSMEVTPWISLTLSNAPNTTDSLDLSHGVHTSSAGTLATDRSLNTGVTRASRLENGSDTSSKSLSMGNSTHTSMTYTEKSEVSSSIHPRPETSAPGAETTLTSTPGNRAISLTLPFSSIPVEEVISTGITSGPDINSAPMTHSPITPPTIVWTSTGTIEQSTQPLHAVSSEKVSVQTQSTPYVNSVAVSASPTHENSVSSGSSTSSPYSSASLESLDSTISRRNAITSWLWDLTTSLPTTTWPSTSLSEALSSGHSGVSNPSSTTTEFPLFSAASTSAAKQRNPETETHGPQNTAASTLNTDASSVTGLSETPVGASISSEVPLPMAITSRSDVSGLTSESTANPSLGTASSAGTKLTRTISLPTSESLVSFRMNKDPWTVSIPLGSHPTTNTETSIPVNSAGPPGLSTVASDVIDTPSDGAESIPTVSFSPSPDTEVTTISHFPEKTTHSFRTISSLTHELTSRVTPIPGDWMSSAMSTKPTGASPSITLGERRTITSAAPTTSPIVLTASFTETSTVSLDNETTVKTSDILDARKTNELPSDSSSSSDLINTSIASSTMDVTKTASISPTSISGMTASSSPSLFSSDRPQVPTSTTETNTATSPSVSSNTYSLDGGSNVGGTPSTLPPFTITHPVETSSALLAWSRPVRTFSTMVSTDTASGENPTSSNSVVTSVPAPGTWTSVGSTTDLPAMGFLKTSPAGEAHSLLASTIEPATAFTPHLSAAVVTGSSATSEASLLTTSESKAIHSSPQTPTTPTSGANWETSATPESLLVVTETSDTTLTSKILVTDTILFSTVSTPPSKFPSTGTLSGASFPTLLPDTPAIPLTATEPTSSLATSFDSTPLVTIASDSLGTVPETTLTMSETSNGDALVLKTVSNPDRSIPGITIQGVTESPLHPSSTSPSKIVAPRNTTYEGSITVALSTLPAGTTGSLVFSQSSENSETTALVDSSAGLERASVMPLTTGSQGMASSGGIRSGSTHSTGTKTFSSLPLTMNPGEVTAMSEITTNRLTATQSTAPKGIPVKPTSAESGLLTPVSASSSPSKAFASLTTAPPTWGIPQSTLTFEFSEVPSLDTKSASLPTPGQSLNTIPDSDASTASSSLSKSPEKNPRARMMTSTKAISASSFQSTGFTETPEGSASPSMAGHEPRVPTSGTGDPRYASESMSYPDPSKASSAMTSTSLASKLTTLFSTGQAARSGSSSSPISLSTEKETSFLSPTASTSRKTSLFLGPSMARQPNILVHLQTSALTLSPTSTLNMSQEEPPELTSSQTIAEEEGTTAETQTLTFTPSETPTSLLPVSSPTEPTARRKSSPETWASSISVPAKTSLVETTDGTLVTTIKMSSQAAQGNSTWPAPAEETGSSPAGTSPGSPEMSTTLKIMSSKEPSISPEIRSTVRNSPWKTPETTVPMETTVEPVTLQSTALGSGSTSISHLPTGTTSPTKSPTENMLATERVSLSPSPPEAWTNLYSGTPGGTRQSLATMSSVSLESPTARSITGTGQQSSPELVSKTTGMEFSMWHGSTGGTTGDTHVSLSTSSNILEDPVTSPNSVSSLTDKSKHKTETWVSTTAIPSTVLNNKIMAAEQQTSRSVDEAYSSTSSWSDQTSGSDITLGASPDVTNTLYITSTAQTTSLVSLPSGDQGITSLTNPSGGKTSSASSVTSPSIGLETLRANVSAVKSDIAPTAGHLSQTSSPAEVSILDVTTAPTPGISTTITTMGTNSISTTTPNPEVGMSTMDSTPATERRTTSTEHPSTWSSTAASDSWTVTDMTSNLKVARSPGTISTMHTTSFLASSTELDSMSTPHGRITVIGTSLVTPSSDASAVKTETSTSERTLSPSDTTASTPISTFSRVQRMSISVPDILSTSWTPSSTEAEDVPVSMVSTDHASTKTDPNTPLSTFLFDSLSTLDWDTGRSLSSATATTSAPQGATTPQELTLETMISPATSQLPFSIGHITSAVTPAAMARSSGVTFSRPDPTSKKAEQTSTQLPTTTSAHPGQVPRSAATTLDVIPHTAKTPDATFQRQGQTALTTEARATSDSWNEKEKSTPSAPWITEMMNSVSEDTIKEVTSSSSVLRTLNTLDINLESGTTSSPSWKSSPYERIAPSESTTDKEAIHPSTNTVETTGWVTSSEHASHSTIPAHSASSKLTSPVVTTSTREQAIVSMSTTTWPESTRARTEPNSFLTIELRDVSPYMDTSSTTQTSIISSPGSTAITKGPRTEITSSKRISSSFLAQSMRSSDSPSEAITRLSNFPAMTESGGMILAMQTSPPGATSLSAPTLDTSATASWTGTPLATTQRFTYSEKTTLFSKGPEDTSQPSPPSVEETSSSSSLVPIHATTSPSNILLTSQGHSPSSTPPVTSVFLSETSGLGKTTDMSRISLEPGTSLPPNLSSTAGEALSTYEASRDTKAIHHSADTAVTNMEATSSEYSPIPGHTKPSKATSPLVTSHIMGDITSSTSVFGSSETTEIETVSSVNQGLQERSTSQVASSATETSTVITHVSSGDATTHVTKTQATFSSGTSISSPHQFITSTNTFTDVSTNPSTSLIMTESSGVTITTQTGPTGAATQGPYLLDTSTMPYLTETPLAVTPDFMQSEKTTLISKGPKDVSWTSPPSVAETSYPSSLTPFLVTTIPPATSTLQGQHTSSPVSATSVLTSGLVKTTDMLNTSMEPVTNSPQNLNNPSNEILATLAATTDIETIHPSINKAVTNMGTASSAHVLHSTLPVSSEPSTATSPMVPASSMGDALASISIPGSETTDIEGEPTSSLTAGRKENSTLQEMNSTTESNIILSNVSVGAITEATKMEVPSFDATFIPTPAQSTKFPDIFSVASSRLSNSPPMTISTHMTTTQTGSSGATSKIPLALDTSTLETSAGTPSVVTEGFAHSKITTAMNNDVKDVSQTNPPFQDEASSPSSQAPVLVTTLPSSVAFTPQWHSTSSPVSMSSVLTSSLVKTAGKVDTSLETVTSSPQSMSNTLDDISVTSAATTDIETTHPSINTVVTNVGTTGSAFESHSTVSAYPEPSKVTSPNVTTSTMEDTTISRSIPKSSKTTRTETETTSSLTPKLRETSISQEITSSTETSTVPYKELTGATTEVSRTDVTSSSSTSFPGPDQSTVSLDISTETNTRLSTSPIMTESAEITITTQTGPHGATSQDTFTMDPSNTTPQAGIHSAMTHGFSQLDVTTLMSRIPQDVSWTSPPSVDKTSSPSSFLSSPAMTTPSLISSTLPEDKLSSPMTSLLTSGLVKITDILRTRLEPVTSSLPNFSSTSDKILATSKDSKDTKEIFPSINTEETNVKANNSGHESHSPALADSETPKATTQMVITTTVGDPAPSTSMPVHGSSETTNIKREPTYFLTPRLRETSTSQESSFPTDTSFLLSKVPTGTITEVSSTGVNSSSKISTPDHDKSTVPPDTFTGEIPRVFTSSIKTKSAEMTITTQASPPESASHSTLPLDTSTTLSQGGTHSTVTQGFPYSEVTTLMGMGPGNVSWMTTPPVEETSSVSSLMSSPAMTSPSPVSSTSPQSIPSSPLPVTALPTSVLVTTTDVLGTTSPESVTSSPPNLSSITHERPATYKDTAHTEAAMHHSTNTAVTNVGTSGSGHKSQSSVLADSETSKATPLMSTTSTLGDTSVSTSTPNISQTNQIQTEPTASLSPRLRESSTSEKTSSTTETNTAFSYVPTGAITQASRTEISSSRTSISDLDRPTIAPDISTGMITRLFTSPIMTKSAEMTVTTQTTTPGATSQGILPWDTSTTLFQGGTHSTVSQGFPHSEITTLRSRTPGDVSWMTTPPVEETSSGFSLMSPSMTSPSPVSSTSPESIPSSPLPVTALLTSVLVTTTNVLGTTSPEPVTSSPPNLSSPTQERLTTYKDTAHTEAMHASMHTNTAVANVGTSISGHESQSSVPADSHTSKATSPMGITFAMGDTSVSTSTPAFFETRIQTESTSSLIPGLRDTRTSEEINTVTETSTVLSEVPTTTTTEVSRTEVITSSRTTISGPDHSKMSPYISTETITRLSTFPFVTGSTEMAITNQTGPIGTISQATLTLDTSSTASWEGTHSPVTQRFPHSEETTTMSRSTKGVSWQSPPSVEETSSPSSPVPLPAITSHSSLYSAVSGSSPTSALPVTSLLTSGRRKTIDMLDTHSELVTSSLPSASSFSGEILTSEASTNTETIHFSENTAETNMGTTNSMHKLHSSVSIHSQPSGHTPPKVTGSMMEDAIVSTSTPGSPETKNVDRDSTSPLTPELKEDSTALVMNSTTESNTVFSSVSLDAATEVSRAEVTYYDPTFMPASAQSTKSPDISPEASSSHSNSPPLTISTHKTIATQTGPSGVTSLGQLTLDTSTIATSAGTPSARTQDFVDSETTSVMNNDLNDVLKTSPFSAEEANSLSSQAPLLVTTSPSPVTSTLQEHSTSSLVSVTSVPTPTLAKITDMDTNLEPVTRSPQNLRNTLATSEATTDTHTMHPSINTAVANVGTTSSPNEFYFTVSPDSDPYKATSAVVITSTSGDSIVSTSMPRSSAMKKIESETTFSLIFRLRETSTSQKIGSSSDTSTVFDKAFTAATTEVSRTELTSSSRTSIQGTEKPTMSPDTSTRSVTMLSTFAGLTKSEERTIATQTGPHRATSQGTLTWDTSITTSQAGTHSAMTHGFSQLDLSTLTSRVPEYISGTSPPSVEKTSSSSSLLSLPAITSPSPVPTTLPESRPSSPVHLTSLPTSGLVKTTDMLASVASLPPNLGSTSHKIPTTSEDIKDTEKMYPSTNIAVTNVGTTTSEKESYSSVPAYSEPPKVTSPMVTSFNIRDTIVSTSMPGSSEITRIEMESTFSLAHGLKGTSTSQDPIVSTEKSAVLHKLTTGATETSRTEVASSRRTSIPGPDHSTESPDISTEVIPSLPISLGITESSNMTIITRTGPPLGSTSQGTFTLDTPTTSSRAGTHSMATQEFPHSEMTTVMNKDPEILSWTIPPSIEKTSFSSSLMPSPAMTSPPVSSTLPKTIHTTPSPMTSLLTPSLVMTTDTLGTSPEPTTSSPPNLSSTSHEILTTDEDTTAIEAMHPSTSTAATNVETTSSGHGSQSSVLADSEKTKATAPMDTTSTMGHTTVSTSMSVSSETTKIKRESTYSLTPGLRETSISQNASFSTDTSIVLSEVPTGTTAEVSRTEVTSSGRTSIPGPSQSTVLPEISTRTMTRLFASPTMTESAEMTIPTQTGPSGSTSQDTLTLDTSTTKSQAKTHSTLTQRFPHSEMTTLMSRGPGDMSWQSSPSLENPSSLPSLLSLPATTSPPPISSTLPVTISSSPLPVTSLLTSSPVTTTDMLHTSPELVTSSPPKLSHTSDERLTTGKDTTNTEAVHPSTNTAASNVEIPSSGHESPSSALADSETSKATSPMFITSTQEDTTVAISTPHFLETSRIQKESISSLSPKLRETGSSVETSSAIETSAVLSEVSIGATTEISRTEVTSSSRTSISGSAESTMLPEISTTRKIIKFPTSPILAESSEMTIKTQTSPPGSTSESTFTLDTSTTPSLVITHSTMTQRLPHSEITTLVSRGAGDVPRPSSLPVEETSPPSSQLSLSAMISPSPVSSTLPASSHSSSASVTSLLTPGQVKTTEVLDASAEPETSSPPSLSSTSVEILATSEVTTDTEKIHPFSNTAVTKVGTSSSGHESPSSVLPDSETTKATSAMGTISIMGDTSVSTLTPALSNTRKIQSEPASSLTTRLRETSTSEETSLATEANTVLSKVSTGATTEVSRTEAISFSRTSMSGPEQSTMSQDISIGTIPRISASSVLTESAKMTITTQTGPSESTLESTLNLNTATTPSWVETHSIVIQGFPHPEMTTSMGRGPGGVSWPSPPFVKETSPPSSPLSLPAVTSPHPVSTTFLAHIPPSPLPVTSLLTSGPATTTDILGTSTEPGTSSSSSLSTTSHERLTTYKDTAHTEAVHPSTNTGGTNVATTSSGYKSQSSVLADSSPMCTTSTMGDTSVLTSTPAFLETRRIQTELASSLTPGLRESSGSEGTSSGTKMSTVLSKVPTGATTEISKEDVTSIPGPAQSTISPDISTRTVSWFSTSPVMTESAEITMNTHTSPLGATTQGTSTLDTSSTTSLTMTHSTISQGFSHSQMSTLMRRGPEDVSWMSPPLLEKTRPSFSLMSSPATTSPSPVSSTLPESISSSPLPVTSLLTSGLAKTTDMLHKSSEPVTNSPANLSSTSVEILATSEVTTDTEKTHPSSNRTVTDVGTSSSGHESTSFVLADSQTSKVTSPMVITSTMEDTSVSTSTPGFFETSRIQTEPTSSLTLGLRKTSSSEGTSLATEMSTVLSGVPTGATAEVSRTEVTSSSRTSISGFAQLTVSPETSTETITRLPTSSIMTESAEMMIKTQTDPPGSTPESTHTVDISTTPNWVETHSTVTQRFSHSEMTTLVSRSPGDMLWPSQSSVEETSSASSLLSLPATTSPSPVSSTLVEDFPSASLPVTSLLNPGLVITTDRMGISREPGTSSTSNLSSTSHERLTTLEDTVDTEDMQPSTHTAVTNVRTSISGHESQSSVLSDSETPKATSPMGTTYTMGETSVSISTSDFFETSRIQIEPTSSLTSGLRETSSSERISSATEGSTVLSEVPSGATTEVSRTEVISSRGTSMSGPDQFTISPDISTEAITRLSTSPIMTESAESAITIETGSPGATSEGTLTLDTSTTTFWSGTHSTASPGFSHSEMTTLMSRTPGDVPWPSLPSVEEASSVSSSLSSPAMTSTSFFSTLPESISSSPHPVTALLTLGPVKTTDMLRTSSEPETSSPPNLSSTSAEILATSEVTKDREKIHPSSNTPVVNVGTVIYKHLSPSSVLADLVTTKPTSPMATTSTLGNTSVSTSTPAFPETMMTQPTSSLTSGLREISTSQETSSATERSASLSGMPTGATTKVSRTEALSLGRTSTPGPAQSTISPEISTETITRISTPLTTTGSAEMTITPKTGHSGASSQGTFTLDTSSRASWPGTHSAATHRSPHSGMTTPMSRGPEDVSWPSRPSVEKTSPPSSLVSLSAVTSPSPLYSTPSESSHSSPLRVTSLFTPVMMKTTDMLDTSLEPVTTSPPSMNITSDESLATSKATMETEAIQLSENTAVTQMGTISARQEFYSSYPGLPEPSKVTSPVVTSSTIKDIVSTTIPASSEITRIEMESTSTLTPTPRETSTSQEIHSATKPSTVPYKALTSATIEDSMTQVMSSSRGPSPDQSTMSQDISTEVITRLSTSPIKTESTEMTITTQTGSPGATSRGTLTLDTSTTFMSGTHSTASQGFSHSQMTALMSRTPGDVPWLSHPSVEEASSASFSLSSPVMTSSSPVSSTLPDSIHSSSLPVTSLLTSGLVKTTELLGTSSEPETSSPPNLSSTSAEILAITEVTTDTEKLEMTNVVTSGYTHESPSSVLADSVTTKATSSMGITYPTGDTNVLTSTPAFSDTSRIQTKSKLSLTPGLMETSISEETSSATEKSTVLSSVPTGATTEVSRTEAISSSRTSIPGPAQSTMSSDTSMETITRISTPLTRKESTDMAITPKTGPSGATSQGTFTLDSSSTASWPGTHSATTQRFPQSVVTTPMSRGPEDVSWPSPLSVEKNSPPSSLVSSSSVTSPSPLYSTPSGSSHSSPVPVTSLFTSIMMKATDMLDASLEPETTSAPNMNITSDESLAASKATTETEAIHVFENTAASHVETTSATEELYSSSPGFSEPTKVISPVVTSSSIRDNMVSTTMPGSSGITRIEIESMSSLTPGLRETRTSQDITSSTETSTVLYKMPSGATPEVSRTEVMPSSRTSIPGPAQSTMSLDISDEVVTRLSTSPIMTESAEITITTQTGYSLATSQVTLPLGTSMTFLSGTHSTMSQGLSHSEMTNLMSRGPESLSWTSPRFVETTRSSSSLTSLPLTTSLSPVSSTLLDSSPSSPLPVTSLILPGLVKTTEVLDTSSEPKTSSSPNLSSTSVEIPATSEIMTDTEKIHPSSNTAVAKVRTSSSVHESHSSVLADSETTITIPSMGITSAVDDTTVFTSNPAFSETRRIPTEPTFSLTPGFRETSTSEETTSITETSAVLYGVPTSATTEVSMTEIMSSNRIHIPDSDQSTMSPDIITEVITRLSSSSMMSESTQMTITTQKSSPGATAQSTLTLATTTAPLARTHSTVPPRFLHSEMTTLMSRSPENPSWKSSLFVEKTSSSSSLLSLPVTTSPSVSSTLPQSIPSSSFSVTSLLTPGMVKTTDTSTEPGTSLSPNLSGTSVEILAASEVTTDTEKIHPSSSMAVTNVGTTSSGHELYSSVSIHSEPSKATYPVGTPSSMAETSISTSMPANFETTGFEAEPFSHLTSGFRKTNMSLDTSSVTPTNTPSSPGSTHLLQSSKTDFTSSAKTSSPDWPPASQYTEIPVDIITPFNASPSITESTGITSFPESRFTMSVTESTHHLSTDLLPSAETISTGTVMPSLSEAMTSFATTGVPRAISGSGSPFSRTESGPGDATLSTIAESLPSSTPVPFSSSTFTTTDSSTIPALHEITSSSATPYRVDTSLGTESSTTEGRLVMVSTLDTSSQPGRTSSSPILDTRMTESVELGTVTSAYQVPSLSTRLTRTDGIMEHITKIPNEAAHRGTIRPVKGPQTSTSPASPKGLHTGGTKRMETTTTALKTTTTALKTTSRATLTTSVYTPTLGTLTPLNASMQMASTIPTEMMITTPYVFPDVPETTSSLATSLGAETSTALPRTTPSVFNRESETTASLVSRSGAERSPVIQTLDVSSSEPDTTASWVIHPAETIPTVSKTTPNFFHSELDTVSSTATSHGADVSSAIPTNISPSELDALTPLVTISGTDTSTTFPTLTKSPHETETRTTWLTHPAETSSTIPRTIPNFSHHESDATPSIATSPGAETSSAIPIMTVSPGAEDLVTSQVTSSGTDRNMTIPTLTLSPGEPKTIASLVTHPEAQTSSAIPTSTISPAVSRLVTSMVTSLAAKTSTTNRALTNSPGEPATTVSLVTHPAQTSPTVPWTTSIFFHSKSDTTPSMTTSHGAESSSAVPTPTVSTEVPGVVTPLVTSSRAVISTTIPILTLSPGEPETTPSMATSHGEEASSAIPTPTVSPGVPGVVTSLVTSSRAVTSTTIPILTFSLGEPETTPSMATSHGTEAGSAVPTVLPEVPGMVTSLVASSRAVTSTTLPTLTLSPGEPETTPSMATSHGAEASSTVPTVSPEVPGVVTSLVTSSSGVNSTSIPTLILSPGELETTPSMATSHGAEASSAVPTPTVSPGVSGVVTPLVTSSRAVTSTTIPILTLSSSEPETTPSMATSHGVEASSAVLTVSPEVPGMVTSLVTSSRAVTSTTIPTLTISSDEPETTTSLVTHSEAKMISAIPTLAVSPTVQGLVTSLVTSSGSE-TSAFSNLTVASSQPETIDSWVAHPGTEASSVVPTLTVSTGEPFTNISLVTHPAESSSTLPRTTSRFSHSELDTMPSTVTSPEAESSSAISTTISPGIPGVLTSLVTSSGRDISATFPTVPESPHESEATASWVTHP-AVTSTTVPRTTPNYSHSEPDTTPSIATSPGAEATSDFPTITVSPDVPDMVTSQVTSSGTDTSITIPTLTLSSGEPETTTSFITYSETHTSSAIPTLPVSPGASKMLTSLVISSGTDSTTTFPTLTETPYEPETTAIQLIHPAETNTMVPRTTPKFSHSKSDTTLPVAITSPGPEASSAVSTTTISPDMSDLVTSLVPSSGTDTSTTFPTLSETPYEPETTATWLTHPAETSTTVSGTIPNFSHRGSDTAPSMVTSPGVDTRSGVPTTTIPPSIPGVVTSQVTSSATDTSTAIPTLTPSPGEPETTASSATHPGTQTGFTVPIRTVPSSEPDTMASWVTHPPQTSTPVSRTTSSFSHSSPDATPVMATSPRTEASSAVLTTISPGAPEMVTSQITSSGAATSTTVPTLTHSPGMPETTALLSTHPRTETSKTFPASTVFPQVSETTASLTIRPGAETSTALPTQTTSSLFTLLVTGTSRVDLSPTASPGVSAKTAPLSTHPGTETSTMIPTSTLSLGLLETTGLLATSSSAETSTSTLTLTVSPAVSGLSSASITTDKPQTVTSWNTETSPSVTSVGPPEFSRTVTGTTMTLIPSEMPTPPKTSHGEGVSPTTILRTTMVEATNLATTGSSPTVAKTTTTFNTLAGSLFTPLTTPGMSTLASESVTSRTSYNHRSWISTTSSYNRRYWTPATSTPVTSTFSPGISTSSIPSSTAATVPFMVPFTLNFTITNLQYEEDMRHPGSRKFNATERELQGLLKPLFRNSSLEYLYSGCRLASLRPEKDSSATAVDAICTHRPDPEDLGLDRERLYWELSNLTNGIQELGPYTLDRNSLYVNGFTHRSSMPTTSTPGTSTVDVGTSGTPSSSPSPTTAGPLLMPFTLNFTITNLQYEEDMRRTGSRKFNTMESVLQGLLKPLFKNTSVGPLYSGCRLTLLRPEKDG--AATGVDAICTHRLDPKSPGLNREQLYWELSKLTNDIEELGPYTLDRNSLYVNGFTHQSSVSTTSTPGTSTVDLRTSGTPSSLSSPTIMAAGPLLVPFTLNFTITNLQYGEDMGHPGSRKFNTTERVLQGLLGPIFKNTSVGPLYSGCRLTSLRSEKDGAATGVDAICIHHLDPKSPGLNRERLYWELSQLTNGIKELGPYTLDRNSLYVNGFTHRTSVPTSSTPGTSTVDLGTSGTPFSLPSPATAGPLLVLFTLNFTITNLKYEEDMHRPGSRKFNTTERVLQTLLGPMFKNTSVGLLYSGCRLTLLRSEKDGAATGVDAICTHRLDPKSPGVDREQLYWELSQLTNGIKELGPYTLDRNSLYVNGFTHWIPVPTSSTPGTSTVDLGSGTPSSLPSPTTAGPLLVPFTLNFTITNLKYEEDMHCPGSRKFNTTERVLQSLLGPMFKNTSVGPLYSGCRLTLLRSEKDGAATGVDAICTHRLDPKSPGVDREQLYWELSQLTNGIKELGPYTLDRNSLYVNGFTHQTSAPNTSTPGTSTVDLGTSGTPSSLPSPTSAGPLLVPFTLNFTITNLQYEEDMHHPGSRKFNTTERVLQGLLGPMFKNTSVGLLYSGCRLTLLRPEKNGAATGMDAICSHRLDPKSPGLNREQLYWELSQLTHGIKELGPYTLDRNSLYVNGFTHRSSVAPTSTPGTSTVDLGTSGTPSSLPSPTTAVPLLVPFTLNFTITNLQYGEDMRHPGSRKFNTTERVLQGLLGPLFKNSSVGPLYSGCRLISLRSEKDGAATGVDAICTHHLNPQSPGLDREQLYWQLSQMTNGIKELGPYTLDRNSLYVNGFTHRSSGLTTSTPWTSTVDLGTSGTPSPVPSPTTTGPLLVPFTLNFTITNLQYEENMGHPGSRKFNITESVLQGLLKPLFKSTSVGPLYSGCRLTLLRPEKDGVATRVDAICTHRPDPKIPGLDRQQLYWELSQLTHSITELGPYTLDRDSLYVNGFTQRSSVPTTSTPGTFTVQPETSETPSSLPGPTATGPVLLPFTLNFTITNLQYEEDMRRPGSRKFNTTERVLQGLLMPLFKNTSVSSLYSGCRLTLLRPEKDGAATRVDAVCTHRPDPKSPGLDRERLYWKLSQLTHGITELGPYTLDRHSLYVNGFTHQSSMTTTRTPDTSTMHLATSRTPASLSGPMTASPLLVLFTINFTITNLRYEENMHHPGSRKFNTTERVLQGLLRPVFKNTSVGPLYSGCRLTLLRPKKDGAATKVDAICTYRPDPKSPGLDREQLYWELSQLTHSITELGPYTLDRDSLYVNGFTQRSSVPTTSIPGTPTVDLGTSGTPVSKPGPSAASPLLVLFTLNFTITNLRYEENMQHPGSRKFNTTERVLQGLLRSLFKSTSVGPLYSGCRLTLLRPEKDGTATGVDAICTHHPDPKSPRLDREQLYWELSQLTHNITELGPYALDNDSLFVN-------GFTHRSSVSTTSTPGTPTVYLGASKTPASIFGPSAASHLLILFTLNFTITNLRYEENMWPGSRKFNTTERVLQGLLRPLFKNTSVGPLYSGCRLTLLRPEKDGEATGVDAICTHRPDPTGPGLDREQLYLELSQLTHSITELGPYTLDRDSLYVNGFTHRSSVPTTSTGVVSEEP--------------------FTLNFTINNLRYMADMGQPGSLKFNITDNVMQHLLSPLFQRSSLGARYTGCRVIALRSVKNGAETRVDLLCTYLQPLSGPGLPIKQVFHELSQQTHGITRLGPYSLDKDSLYLNGYNEPGPDEPPTTPKPATTFLPP----LSEATTAMGYHLKTLTLNFTISNLQYSPDMGKGSATFNSTEGVLQHLLRPLFQKSSMGPFYLGCQLISLRPEKDGAATGVDTTCTYHPDPVGPGLDIQQLYWELSQLTHGVTQLGFYVLDRDSLFIN------------GYAPQNLSIRGEYQINFHIVNWNLSNPDPTSSEYITLLRDIQDKVTTLYKGSQLHDTFRFCLVTNLTMDSVLVTVKALFSSNLDPSLVEQVFLDKTLNASFHWLGSTYQLVDIHVTEMESSVYQP----TSSSSTQHFYLNFTITNLPYSQDKAQPGTTNYQRNKRNIEDALNQLFRNSSIKSYFSDCQVSTFRSVPNRHHTGVDSLCNFSPLARRVDRVAIYEEFLRMTRNGTQLQNFTLDRSSVLVDGYSPNRNEPLTGNSDLPFWAVILIGLAGLLGVITCLICGVLVTTRRRKKEGEYNVQQQCPGYYQSHLDLEDLQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0M105-1", "uniprot_id": "A0ABK0M105_RAT", "id": "A0ABK0M105-1", "name": "SEA domain-containing protein", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGQEDLPCSAHQCRYLLTLTASLLLTYGPEMEDGMQYHTEISNETAHEDTAGLDKGPLASISPGNHKDLTTEEAVKAETTATALKVTSIFNSNTKMSTANSRPSTHLKTSEKTTNINTAEMIITASDTSQNLLEIAPSFSTGLRENTSMISRRSSPPYSREPEITIPYITS---------------------------LKTKTIPNVYTLTAPSSESDTISWITHDLEITSAVAKTTTNASQVESDSMVSIATNPRGEHSSNISTAAVFPAIPD---------------------------------------------------LASIEQVSRLFDPTIAISSSISEMKNVDSHSSKEDTRTSKPILTNSPSEPYNTISLISYAGGKTGSPMSTITVSP----------------------------------------DVREIMRPLFPSSGNTNHTRNQPISQGQSKTTTSWITHPGTEVTSRVLTTTISPNIQEMVTSKSVNPTAKLQTTTSLIIDGEEHPSLATSTRAVPLGVIEEMPPPLINMSTEKNAR------------------------------------TSTLDFFLYQPETTTSWTTNPEKETILGIHTTNYSPS-------------------------------------------------VTDRMTSINLNYTPSEPESIKSLDIHVEGNPSTSMSIQTVLPSIREMMISQATNYGREKHISTSALPVSLGQRQTTASLVNHAENEATSEALPTTISTIQGMSSTTRMTSEPHTTASLVTHNGEQHS----------------------SDMSTLPASSGITKMKQPLETSTGKENQSVFTILAVSLGVPKTKSINTTSNILDMIISKAQNHTSSDGHTITSLVTHAGTQSSLS-----------------------------------------MSTEAPSSSITKLTASLFTDMGKEDVAITSLPISSGEMG-----------------RRAPSVTKPEKEVTSEDQSITISNSIQQIMTSPTVIPTEPHTIVLVDTHFG----DQPSSAMSTLPVTSDLTKIIPSLSTRPGTESHSVTSTMGISEGQLETTTLGDTHTGREGNSLTLSAVISTSAPDIMISTTKNETTSDTQTITSLITLVEEHHSLSVPTQG----------DSPGIMKETSSLFTDLGTESYTMTSTLPVFSGQP-NIRKTWVKHSETEVTAGILPTTILTSIPEIMASPTSLLSEPHTTVSLISHVGGEPSLAMSTLPVSGTLTENIPSEVN--------YPGIEGHSMTSALDGTRDHIDSTDQWVSHHSKEGTSMVLYTTISTSAPDMVVSINKNQISSDTHTVTSFITQAKGQPSLSG------------------------------------------STQDISPAIKEVPQSIFNDSDTESYAVTSTLPASSHEPETRTKWIPNTKMEDKLG------------------------------------------------VLSTTISSSTPEMMISPTPITSEIHSTVSLFTHVGEQDNIAMSSLTVSPSITKFTATQQTHTDTESHTETSALNVSTGQAESTTTWLTQSAKKETTQVLSTTSPTVSDVMTSATLYSTSPGTQTITSFISNDGEQSS----------------------------------------------------------------------------------LPTSTQGISPGITKG-----------------------------------------------IPSLFTNLNTESYSMTSTMPVYSGQPDTMT---------------------------------------------------------------------------------------------------------------------------------LWDTNSEKEVTAGDLATTISSSVLEMKTSKTTFLTESHTTIPSIS---------HVVEQHNPVMSTLPVSTGIKEIIPS------------------------QGTHSDTENHSLTSALNVSAGQAESTTTWLTQTAKRETSG---------------------------------------VLSRTMSPTVPDMMTSAPLNNTSPSTQTITSFISHDGEQPSLSMSTQDISAGMTEGTPSLFTALNTKSN---------------------------------------------------------------------------------------------------------------------------------------------AMTSNMPASSGQTESRTPWDTNSEMKATSGTLSNTISYNVPEMKILPTVLPSETYSAKVPLVTEVVGQHSSVMSTLP------------------------------------------FSPGRTESIPSLETTSGTENYSVTSTLDMSIDQAGSTTPWGTHTG------------------------------------RKNNLVGTSTIISTTALEMMTSISKNQASSETQTITSFINHAAGQPSLSGSTQGISSGIKEMTPSLFTDLDTDSNVMTSTMP---------------------------------------------------------------------------------------ASSGQAETRTPLGTTSEMKVTSGTLSTTISYTVPQMMASATFLPSE--------------------------PHTTVPLVTHVVGQPSSVMSTLPFSP----------------------------------------------------------------------GRTESIPSLEISSQIENYSVTSTLDMS--------------------------------------------------------------------------------------------------------------------------------------------IDQAGSTTPWATHTEKEGTSGTPSSIISTSAPDRMTSITKNQTSSETQTISSLISHDEGQHNFSVYSHNISPGIREVTQSLFTDLGKNSYAMNSTLPASSSQAEIRTPWDSNTEMKDTSGTLSTTISYTLPQVMTSVTVIPSEPQTATVSLVTHAVGQPSSVMSTLSFSPGRTESQS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SLVISSDIENYSVISTLDMSIDEGSTTPWGTHTGREGTSGTPSSIISTSVTEMMPSITKN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QTSSKTQTITSFISHDDGQPSISVSTKGISPGIEETTPSLFTDLGPDSNVMTSAMPASSGQAESR-----------------------------------------------------------------------------------------------------TPWDTTSEMKSTSGTLSTTISHTVPEMMTSATFPPS-----------------------------------------------------------------------------ETHITNPIVIDIVGQPSSVKSTLP---------------------------------------------------------SSPSRTESMPSMDTSSHTENYSVTSTFDKSIDQAGSTNPWNTHTD--------------------------------------------------------KGSTSGTLSSIISTSAPEMMSSITKDQTSSETQTITSFIS------------------------------------------------------------------------------------HDDGQPSISVSN--------------KGISPGIEETISSLFTDLGPDSNVMTSAMPASSGQAESRTPWDTTSEMKSTSGTLSTTISHTVPEKMTSATFPPSETHITNPIVIDIVGQP--------------------------------------SSVKSTLPFSPSRTESMPSMDTSSHTENYSVTSTFDKSIDQAGSTNPWNTHTGKGSTSGTLSSIISTSAPEMMSSIPKNQTSSATQSITTFISHDDE------------------------------------QPSLSMSTQGISPGTKQMTPSPFTDLGPGSYAMASTLPASSVLAETRTPWDTTSEMKGTSGTLSTTVS-----------------------YSVPEMTTSATFLPSEPHTTIPIVTHVVGQPSSVMSTLPLSPSRTESMPSMDTSSHTENYSMTSTLDMSIDQAGSTNPWNTHTDKESTSGTLPSIISTSAPEMMSSIPKNQTSSATQTITSFIS--HDDGQSSLSVSTKGISPGIKEMTPSSFTDLGPGSYAMASTLLAFSG--------------------------QAETRTPWDTTSEKKSTSGTLSTTISYTVPEMVTSATFLPSETHTTIPIVTHVVGQPSSVMSTLPLSPSRTESMPSMDTSS--------------------------------------------------------------------------------------------------HTENYSMTSTLDMSIDQAGSTNPWNTHTDKESTSGTLPS--------IISTSAPEMMSSIPKNQTSSATQTITSFISHDDGQSSLSVSTKGISPG------IKEMTPSSFTDLGPGSYAMASTLLASSGQVEARTPWDTTSEMKSTYGTLFTTVSYSVPEMTTSATFLPSEPHTTIPIVTHVVGQPSS------------------------------------------------VMSTLPLSPSRTESMPSMDTSSHTENYSMTSTLDMSIDQAGSTNPWNTHTDKESTSGTLPSIISTSAPEMMSSIPKNQTSSATQTITSFIS---------------------------HDDGQSSLSVSTKGISPGIKEMTPSSFTDLGPGSYAMASTLLAFSGQAETRTPWDTTSEKKS------------------------TSGTLSTTISYTVPEMVTSATFLPSETHTTIPIVTHLVGQPSS-------VMSTLPLSPSRTESMPSLDTSSHTENYSVTSTLDMSIDQAGSTTAWAIHTEKESTSGTPSTIISTSAPDRMTSTTKNQTSSETQTISSFISHDEGQPSLS----------------------------------MSTPSISPLMTEVTQSLFTDLGTDSYAMTSTLPTSSGQAHSSPPWDTNSEMKTTSATLSTTILSTLPEMMTSASLIPSEPHSTVPLFTHVEGQPSS-------VLSTLLISPGITEVMSSLVTSSATETNSVTYNMDISTEQPGFTTPWGTHS---GKESTSRTLSTIISTSAPDRMTSITQNHFSSDTQTTESLNTHGGGYHSLLLSSPNIISDITRVTPELFTTLSTESYTVTSILPASP--------DQGETTAQLLNQPVKESP--SVVLPTTISTSVSEVMTSPLSELHTIDSLVTHVGGQLSS------------------------------------------------------------------------------------------------------------MSNFTVSPGITEIISSQDTSYVTESHS----------------------------------------------VTSVLALSPSPLATTSPWETHPSREAISEILTINTSPSAIDSMTSKSKIHSSSE------TQSIISTVTHGEVQPSMSVSTQASSPSITEVTQLLSTDLGTGNYSIASTLPASLGQTETKAPSVTNLETEVTSG-------------------------------------------------------------------------------------------------------------------------ALSTIISTIVSEMMTSS----TVSPHTTASLVSHVGEQPSSTITTLPASPDR--TEIIPSLVTHPGTTSHIVSSPLDISPGQAESTAPWVTHSGNEGYSG-------------VLSTTILSSVPGMMTSKTQNHTSFDTQTITSFITHAEEQDSLSLSTQGVSPSITEVTPSLFTELDTEKSAFPSTLPVSVFPPGSKTTSVTHPQTEVTSGSSIIITAN-----------------VPDMMSSPTLIPSDPHTTVSLVTHVAEQPSSAMSILPVSPSTTETISPLVTHSGTESHSVTSTLAVSS-----------------------------SHSETTPQWITHTGHEGTSGTLPTTTSSSIPDIMTSTTLN-------------HTLSKSQTVKSLFTHVGGQPSLNMTTMAFSPSIPKLTTSPSTKFITESHPTTVALSSSLS----------------------------------------------------------------------KTTASLVTPQMESTLSFLTTTIPSTILEMITPPSLLTSELHTTISLATPLEGQLTSSTSTLAISSGVTEKIPLLVTSSTTEIYSVSSTLDTSPG-LESPDSMDTTPKIEATSNILSTDISPS-------------VPDLMSSPTHIPFEPHATLSLATYVGEQSSSNISTLTHFPGIKNIVTPLATTSLVEPHTTVPTLSVPADQRETTALSVTHSGKEVMSTVSSPSTLPGDPERTETWVILSAKTSTPHPTTNFPFSY-------SDTTSSASEVETSSVTTLLSGASEEATSLSVHIGTTTSTTTLTVNPSSILPGSTGFWPSSPSTEYTLTVSSLLPGFSDHPTTSKSSTATSQNIEMSPSLSTIRHSDFVSDVISPTVTLLPSES-------------------------------------STHALTDLETTNEATHSATTSSRPTEAEITTTLHGSSFALLTTSRTSTLSP------------------------ENVTSRPTTSIHPELVPFIFNLTITNLPYTTEMGHPNSLLFNRTEAALKLLLQSLFINTSIG-----------------------------------AGYSGCKLTLIRSEQNGTATGVDTICTYHSDP-------------------------------MSHPLDREKLYQEVTQLTNGITRLGPCTLDKDSLYINGYNHRYWIPTTSTTSPSLVHFTLNFTITNLHHSEGMGSQGSDIFNNTERILNHLLKPMFKISSIGSLYSRCRLISLRPEKDGTATGVDAVCTLHSDPLGFQLDREKLYWELSNNTQGGTKLGSFTLEKDS------------LYINGFTYKRISASTLNTPVTSSLFLMETSTAKPILSTGPGSSLVPFTINFTITNLKYEEGMNYPGSWKYNATERILQRLLRPLFNKTSIGLLYSDCKLALLRP-----------------GRDGTATATGVDAICTYHADPTAPGLDNERVFRELSN----------LTNDVTQLGPYTLDKNSLYINGYTQQILSSTATPTSPSLLHFTLNFTITNLHHTEGMGSQGSEIFNNTERILNRLLKPIFKNSSIGHLYSGCRLISLRPEKEETATGVDAVCTLHSDTLGLQLDREKLYWELNHNTQSVTKLGSFTLEKNSLYINGFTYVRTSDSTLNTPVTSSMFFTETSTAKPIFSTVSYSPLVPFTINFTITNLKYEEGMSHPGSWKFKATERILQRLLRPLLNKTSISLLYSDCKLALLRPGRDGTATATGVDAICTYHADPTAPGLDNERVFRELSNLTNDVTQLGPYTLDKNSLYINGYTQQILSSTSPP------------------------AGPVLEHFTINFTIINLKFEEDMRNPGSRKFNITQRTLQSLLRTLIKKSSIGALYSSCRLSLLRPENDGTGTGVDAVCTHYPDPTGHGLDRKMVYWEISRLTYGVNRLGPYTLDEKSLYVDGYTRQIVATTTQTSMMTIASMGMISN----SSNPTAGPVLVPFTINFTVTNLEYVEDMGHPGSRKFNATERVLQKLLRALFSKTSISSLYSGCRLTLLRLEHNGTATGVDAVCTYHSNVSNQGLDRERLYGELKRLN--IMELGPYTLDQNRLYVNGYKQKILATTHRPSVLATVSEG--TPNISSAPTAASPVLVPFTINFTITNLEFEKDMRYPGSRKFNITERILQSLLRLLFNKTSAGRLYSGCRLVLLRPEKNRAATGVDVICTYHLIPSGNKLVSEHIYGELSSLTQGVTQLGPYTLDQNSLYVNGYTNHILAT---TPRVSMLSNVSSNTANPISNPTASSSALQLCTLNFTITNLPYMNDMWVPGSAKFNKVEKILKLLLKPLFQNATGGPLDSGCRLTSLRPKEDGEATRVDMVCTYHPNSTGTALDSKQLYLELEQLTHNITQLGPYTLDQNSLYVNGYTHQTAVTSPSKS------------------------SLELFTFNFTITNLQYTKNMQPAGSKKFNIMEKILQGLLGPLFKNTSIGPLYAGCRLTWLSSRKDGKATGIDTVCTYYPDHMGHGLATEQLYLELSNLTHGVTQLGPYTLDQDSLYVNGYIYSASGIVLN---TTTSFPAFSLAPSSTNNSTDNGTVMVPITLNFTITNLHYTEEMGHPGSLKFNSTKWILHYWLGTLLNKTSIAPVYSGCRLSSLRSENHRATTGVDIICNFHSYSMSPRVNQDQLFWELSHGTHGITRLGPYTLDQDSLYINGYSFGAAALNTTTG----------------------ELSEELFTVNFTINNLRYSADMSQIGSPKFNITDTLMQHLLSSLFQRSSLGPLYTGCRVDTLKSVKNGAQTQVDVLCTYHQVFNSRGLPAKSIFYDLSWQTHGITKLGPYSLDKDSLFINGYNEPGPDVPPTTPEPATTILPSSTSSLQPESNTAMWHNLETFTINFTISNVPYSADMIS-GSAMFNSTENVLQHLLGPLFQNDSFN---SSCRLTSLRPEKNGTSTGVVTTCTYQHDPGQAGMDTQGLYSELSHLSHGFTQMGNYTLEAHSLYVNGYHVLGPDILTTTPEPSTTILPFTLTSMQPESTTAREHHLEIFTINFTISNLPYSADMDYS-SALFNSTESTLQHMLRPLFQNISFN---SSCKLASLRPRKNQNSTRVNIICSYQNDSAHPALHIQELYSELSHLTHGFTQLGNYTLDKDSLYVNEDSLYVNGYNETGTKEPTINPDTAPTLLTSSSTFVQTESTTVVGHHLKTVTVSLTISNLPYSAHMNNDSAVFNSTETVLKHLLEPLLRNMSFN---SSCRLDSLRPKKNGTATAVEAICTYFHDPANPGIDTQRLYTELSHFTYGITQLGNYTLDNESLQVNGYSETHPEESPTTPEPATTLQPSPSTSLHPEPTTEHHLKILTINFTISNLPYSSNMSN-GSAMFSSTESIVQQLLGHLFQNDSFNS---SCRLDSLRSKKNGTATGVDVICTYHRDPAHPEMDIQGLYLEMNNLTYGITQLGNYSLEKNSLYINGYNDHSTEDLYTAAESPTTILPSPSTFVQGEPTMAMGYLKTFTLNFTISNLPYSADMNTGSATFNSTERILQYLIRPLVQNE---SLYSDCRLASLRPKKNGTATGVNAICSYHLSPEHPELDTQELFTKLTQLTQGVTQLGSYMLDQHSLYVNGYPHQTAEITPSGYVPLNVTIQGKYQINFCIINWNLNNTDPTSSEYIMLERDIEDKVTTLYTGSQLKEVFLSCLVTNMTSGSTVVTIEALFSSYLDPNLVKQIFLNKTLNASSYWLGATYQLTDLHVIDMKTSILLPTEIPTTSSNAQHFNLNFTITNLPYSQDIAQPGTTKHQQSKRSIEYALNQLFRNSTIKSYFSDCQVLAFRSVSNNNHTGVDSLCNFSPLARRVDRVAIYEEFLRMTQNGTQLLNFTLDRKSVFVDGYSQNRDDDVMKNSGLPFWAIILICLAVLLVLITCLMCCFLVTICRKKKEGDYQVQRHRLAYYLSHLDLRKLQ", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . *** : : :::* : . . :: : .. : * * *. . *. . :* :* * . :. :* . . : * ...* ..* *:: : :::*.. . . :** .:. *: : *.:* ..::* * :*: : * : :* . .** ::* : . : .:* .:*: *.*::: : .. .. *. *: : ***:.: . *:.*: *:: :** *.: :.: :* .: :. : *.: * .:: * . :* . : ** *::.* . . *: : :: * *: .. *:* .. .:*.*. .:::. .:** **: ...::: .*. : : .*: . ::.: :.. *. . * :*. :. . ***: :: * :.*. :.** *::. ..: * : * * . .:: ....*:.::. . .: .. ::: .*:*: ***.: : . .* . . ** .:. . . :. .. : :* ::* : :* ..*: :*: : .::* *. .* * : :*:.: **: : :..::.: .:* ::. : ..:* * .:**:* : :.: : ::. .:*. .:*: :::. **.:* * : **:**.. ** *.:: ::. *. .*. **:.. .:* : ..:: .::. ...* ..: * .: ** :. ....:: : .**.** : . * * : ***: .* ** :. *.. ...: .. ** : ** .*... :** * :: **:. : . ...:*. ..** . : *::*.. : . * .* .: ** * . .* *: * :::** *.. . *.: . : . . . *:** .: :::* : : :*.*: .. . :.: .. .*. *. .* *.**: **:. .**. :.:: .. ::: : .::: .: : : :. ** .. *:*: : .. .*:* :* * **. *. :::. :*. . * : *.: ***. *..:*:. .* *.* .. .. : .*:* **. . : ::. * .:: :*:: **. * :.. .. *.::: : .: :...: :*:::: . :. : : ..: ..: *:. :..:** :** *. : . :.:. * ****. ** * .*:::. * **.:.:*:.: ::*: *.* .*::.: :: .:** :: : . :**:*. ** .*: : :**** . :: * ..: .:: . .:* : .: .***. : * * .:::**: . :* * : :** * : * :* .* : . * *:. .*.:::. :*: ::::. :.*.:*:. . :*.* *: . : :* .:.. * : *.: * . :: *:.: : : :* : ::. : *. . ::..: ***..::: .* : * . :* *:. : :* : .. .***::..: *.:*:.: :*.::* . ::.: .*. * : : * : :* * : *::. :* .:** .:* *.:.:.: . *: * .*. * :: : .: ** *:.* *:** . : : * :::* *. ** **** ** * : * : : : :. : **:. ..* ..* .. .* : .:. .. :.: ...* ..* . :*: .* : ::.::**:**.: * :.:..:: : * :*:.:: ** *. . . .. : **.:. .:.** : . *: .::* ::: *:: . *: .**::... *:**: *: ** **. :*:* :.:. : . * :.* . **:..* : ..:: *. .* ..*..:** :. : : : :..::**:.*:: * *. *.. ..: * :*:.: *: .. : * *.*.: * .:.:* *:** ::*:.:* : :::*.*:** . : :**.:: * ** : ..:..: .*..*.. ::* .** .: :*:** : *::.:* *: :*::*. :** :: .* : .:**::. : *:.*:*:*. ..::.*:.** ** . ..:...: * :*:.: *** :: . :. * .. .* :* : .* *. ::. : .*.* * . . :*:.. : . .* :** :. .:::* .:: :: *:.* . : . . :.:: **: ** *: .::** *: :::* * .* : ** * :. :.. .. * * : : :::* * *. ** :. : ::.:.* . :*.** *. :* :* *.: : :.*..:. . :* .*:.*..* * *. .::: .. * ** . . : * .. .:* *...:* *: :.::*. : * *.:.: *:. :**::: . . *..* : ::.. .*. :* .*.... :* : : :* . * . ::: *. .* *:.:: . * ** :::*: *: .*: . * . :**:* . *.: :**..: :** : .:*::*.: * . ..** * . *:.. ..:. *.* : ::* ** *. ..**: :**.. :. : . .* *.* : ..:*..: :.:* : :.:*:*: .. : :*.*::. * * : *::* .... * .:*.*.* * : . *::. . .** .*:.*..* * * *. .::: . . . * ** . . : * .:*:*...:* * *.::*. : * *...: *:. .:**::: *:. :: ..:*: : : * *.:*..: ..: : *: .** ::. :* *:*. :. *.* .* * :.. . ::*.* . . : * *:: *** . **:.*. * :. **. .:* * : . . * * .: .: *. *** **: . : ..**. .. ..* : * . *:. ....**: :.*..: :* . * .:*.: * :.:* :. : *. :* **::: : *.*.: *: :: . *:* * . .:*: . .*: ::**: *. :* *:* ***.:* *.: *: * : . :* . *:*. * *.. *::* : *:: * . .: *. :* * :.. . :. * :* *: * * .* :: .:::.**. **. ** * .** :*.:* .* : . : . . *. * .**. :* . *** *.::.*..*.:.:.::: . *. **.. *.::.. .* . ::** :* ::... :::.... .* :* * * *: ... .:* ** ::: * * : *. .: * : ::* :. . ** : *:.*:*. .* * : *** :*** :: . *.**:**.: :* :.*:::. ..* . :* .***::.*: * ..**:*..:.::**.** *..: : .:*:* * ..: :: . * :. : :::*.::* : : * ::.* ** **. .: :*. .*::* *:* . .. *.*:: . **.: *:*.. :.: ** *.:*:* .***** *.***:. .:**:.:. ::.:** .::: :.. :*: *. *:*:***. * * *.:*.. ..*.*:.:*.::*. . . : .:.:*. *: * * :.* :.* :.**.:* :.** *. : : .* *: **. .:*.. *:*:: ..:: *.*: ... *.. * ..**.** *:**. .: :*:..* ::*.**: :. ***** : :. . * *.. *:. ** *: :**:* :*:.. . . .. :.: * . **.:* **.*: : * *.**: * ::.:**.*.*:* * ::...*:*.:.* ** *:*.*.*. *.*.: :. .*:* . : * .*::*:. * *. **: * .**. :* .:: **: .* . *** . * *:* ** *. . :*. * : * : : **. *.:*. . :..* *** . * :..:.** * *.*:::. ** ::: *. * . * : :: : :*:: ** :* . . ::: *: .:.*.*: * * :: .**:* *:: :: .*. :. . *: . * ..*:: . * :. .*::. .. .* : : *. ..*:*.: *: . .:* * . : *:: *..::: .* : : . :.* *. :*.:* :. : : : ::...: :.* : .* . * . .:::.: : * *: * :..* * . :** .:. *.. : .*.... * :. : . : *:: .: .::* : : .*.* . **:.. :: * *:. *: . . * .:. ..* : : : . .. . . . ::**. .: *: * ..:: * : * . * .* * . * * . : .* : * : . :.*:::.* * :: **********:: *.* **. ** *** *: ****:*:***: :******* ******:.:**.***:** :.*. .* ****:*****.: *:.: :**.:**::****:****: : :* .. .:: . *. :.:.. .*.: . *:***:*******:***.* :.** **:: * :** **:**:::**:. ***.*:*:**** :** :*********:: **.:***:.*::: ***:****: :*******:****:**:*:* **:.. ***:* **:**** **:: *** :******* *:*.**.** .::*::*:*.***.***: **.*:**:.*****:* *: **.. **:*: :***:*:** *::.*******.:****:*:*:: ..*:.*. : ..:* .. .* .****:** **:***:***:* *** :*******:******.** .:*.:**:. *********** *::*:******:**:: : .. *:***:** **.:*. * ********:* *****:.: * ..* .. :**. * **. .:**:*.*:*****:*******::*:**: ******* ***:***** :*::**.* *******.***.**: ******.***::* *.. : *::* ***.**:*:.:*******:*******:*:: *. ** .* :. :*.*...:..**::.. * ********* * :** *** ***..*::*: ** *:*:*:: * * ****** ***:::* ** :* :*::: :.....*: :*** **.****.*.:*******:*******:**:::*:..*.. * **:********* ::*: .**:*** *::***********:*:****:**** * *.*** ***:*::**:: : . ** **** :**::*:*:.:*******::******: : :**:. . *:* . * :**.. ..* .*.::**:*********:* *:****** *** *: :*: * .*::.**:.*:******: **.*:. .:* ** **..:. . * ::::**:****: **.**.*******:****:**:: ::. .*:* **:****.**:*. ** : ** *** *: ::* ** .**:.:*:..**:***: *:. *:** *:**.:**:: :* ** : :::.** *****:****:**:.**::**:.. .. ... **:.:* *.:* :. . .. : * *******:*: *. :* ** **:**.*** ** *:*:* *.. *.**** ***:*:*::* * : ***: ** ..*:* : ** ***:*:*.:*::* ***: .******: .. *: * ..*. * : *.:. ..:* . * :**:****:** *. :*::. * **:** .** :**.**:. *.. *.*:*: ***.*: .:* *: **::: *. * *. ::** ***:***.:*:** *:**:***:** *:.. .: ..* .*.*... * :*.* .. ..:...* * .*:.:**:** *. :* .* **:** **: **.**::* *.. *.*** ***:*:* **.*:****: **:.**:* ::** ***::*:.**:** ****.:** ***::. . :.:* : :*:****.** * ::*.: ** *. *:.::*:**. ***..*:.: .**: :*** ***: * **::*** : : * : *: :: *:.: *:***:** ***:*:***:****: ..:: *:.:..**:**. :. .* :***:********* **.**..********* :**:*:***.*:. .:* .*:* ****:*:*:****:: *:** .* * ** *:*: :*:***:****** *:**:.**::* **.* *::*:*:***** *:****.*.******** * ***:*******.****::.* *****:* .*.:**::***** ***.**:*:**:****** :***:****.*:** :*::*: * *:**.:*** ************* ******::*:.**.** *********:********** :****.*.:******************************:***** ******.**:***** **:: : **.*****:*** ** ** :****:* .*** *:****:*:**:: .** *****..**", "identical_positions": 2270, "similar_positions": 2718, "identity": "15.59%" }, { "cls_id": "homologset.agr.RGD:1308423", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZY89-1", "uniprot_id": "D3ZY89_RAT", "id": "D3ZY89-1", "name": "Transcription initiation factor TFIID subunit 8", "aln": "MFTELFYKAGPQAPPFATSPPHNYKSRRALRSRTLRESKMADTAT---GPGGSGTRPGN-KQSTNPADNYHLARRRTLQVVVSSLLTEAGFESAEKASVETLTEMLQSYISEIGRSAKSYCEHTARTQPTLSDIVVTLVEMGFNVDTLPAYAKRSQRMVITAPPVTNQPVTPKALTAGQNRPHPPHIPSHFPEFPDPHTYIKTPTYREPVSDYQVLREKAASQRRDVERALTRFMAKTGETQSLFKDDVSTFPLIAARPFTIPYLTALLPS-------ELEIQQMEETDSSEQDEQTDTENIALHISTDESGAEKENTSVLQQNSSLSGSRNGEES-TIDNPYLRPVKKPKIRRKKLTRKRVLESLTISFHSPSCRSRERNQPAGAALSWTLPTLETRARYFPSWCSWFSPLQFACVIVPSLSEVVLFNCEQTIYVFSTELERQKKI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EQH4-1", "uniprot_id": "TAF8_MOUSE", "id": "Q9EQH4-1", "name": "Transcription initiation factor TFIID subunit 8", "aln": "---------------------------------------MADTAA---GPGGSGTRPGS-KQSTNPADNYHLARRRTLQVVVSSLLTEAGFESAEKASVETLTEMLQSYISEIGRSAKSYCEHTARTQPTLSDIVVTLVEMGFNVDTLPAYAKRSQRMVITAPPVTNQPVTPKALTAGQNRPHPPHIPSHFPEFPDPHTYIKTPTYREPVSDYQILREKAASQRRDVERALTRFMAKTGETQSLFKDDVSTFPLIAARPFTIPYLTALLPS-------ELEIQQMEETDSSEQEEQTDTENNALHISTDDSGAEKESASVLQQSSSLSGSRNGEES-VIDNPYLRPVKKPKIRRK--------KSLS--------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z7C8-1", "uniprot_id": "TAF8_HUMAN", "id": "Q7Z7C8-1", "name": "Transcription initiation factor TFIID subunit 8", "aln": "---------------------------------------MADAAAT-AGAGGSGTRSGS-KQSTNPADNYHLARRRTLQVVVSSLLTEAGFESAEKASVETLTEMLQSYISEIGRSAKSYCEHTARTQPTLSDIVVTLVEMGFNVDTLPAYAKRSQRMVITAPPVTNQPVTPKALTAGQNRPHPPHIPSHFPEFPDPHTYIKTPTYREPVSDYQVLREKAASQRRDVERALTRFMAKTGETQSLFKDDVSTFPLIAARPFTIPYLTALLPS-------ELEMQQMEETDSSEQDEQTDTENLALHISMEDSGAEKENTSVLQQNPSLSGSRNGEEN-IIDNPYLRPVKKPKIRRK--------KSLS--------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6P0T2-1", "uniprot_id": "TAF8_DANRE", "id": "Q6P0T2-1", "name": "Transcription initiation factor TFIID subunit 8", "aln": "---------------------------------------MADSVMMGSGSLNSGSRSGSSKTCTSPTENYQLARRRTLQVVVSALLTECGFDSAEKAVVETLTEMMQSYITEVGRCAKANCEHTARSTPTLSDVVITLVEMGFNVDTLPVYAKRSQRMVITAPPITNAPVVPKSLTAGQKRTHPAHIPSHFPDFPDPHTYIRTPTFREPVSDYQVVREKAASQRRDVERALTRFMAKTGETQSLFKDDISAFPLIAAKPSPIPYLSALLPS-------ELELQSLEETDSSEQDDQMDNDNNTSHIMQDDSGADKENE-VLPPGGVVPSGKANEEN-MIDNPYLRPVKKPKVRRK--------K-----------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VWY6-1", "uniprot_id": "TAF8_DROME", "id": "Q9VWY6-1", "name": "Transcription initiation factor TFIID subunit 8", "aln": "---------------------------------------MEKVEA----------------VTVSNVDPY----RRILNKVVSQLLLDKGAGQASNHSLETLTQMLQALIWEIGNSAHNYCELSGRTMPTVGDVSLALINMGISISNLDPYMRKETHVPIPLPPQQTQQRPLSLLQAGIKAPHPHYVPSYFPPMPDPHAYIRTPTHKQPVTEYEAIREKAACQKRDIEKALTKFLCKTTETNNLFPTEDNMFPLIACKPAFPPYAAALNPTDQVFDFEELEYHYLVANRTEDEPSKDDGEEGDSENEEMDGDKSKEEKPELDIKPNSNTNKAILENPNIDNPYLRAATLPKRSKNCPTPG-TMPSRSLATTAPTIRTPSTLEITKTNL-----------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . .. .: * ** *: *** ** : * .*.: :****:*:*: * *:*..*: ** :.*: **:.*: ::*::**:.:..* * ::. :: *. ** . . * ** : .** ::**:** :****:**:***.::**::*: :*****.*:**:*:***:*:.** **:.** : . *****.:* ** :** *: *** : : . :.:: .: * :: . :.. .**. * .: *. *******... ** :: ", "identical_positions": 104, "similar_positions": 96, "identity": "23.27%" }, { "cls_id": "homologset.agr.RGD:1308424", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A2AS89-1", "uniprot_id": "GDAH_MOUSE", "id": "A2AS89-1", "name": "Guanidino acid hydrolase, mitochondrial", "aln": "MLRLLRSSWARGLGSGVATWRPSAGLFRPGCPGIRQASGASDTPHHQSPSSESPVQPVGVGVCSMMRLPLQSSPEGLDAAFIGVPLDTGTSNRPGARFGPCRIREESLMLGAVNPSTGALPFQSLRVADLGNVNVNLYNLQDSCLLIREAYQNVLAAGCIPLTLGGDQTITYPILQAVAKEHGPVGLVHVGAHTNTTDKPREEKVYHRTPFRRSVDEGLLDSKRVVQIGIRGSSRTLDPYRYSRSQGFRVVLAEDCWMKSLVPLMAEVRQQMGGKPLYISFAIDALDPAYAPGTGTPEIAGLTPSQALEIIRGCQGLNVVGCDLVEVSPPYDLSGNTALLAANLLFEMLCALPKVTTV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q0D2L3-1", "uniprot_id": "GDAH_RAT", "id": "Q0D2L3-1", "name": "Guanidino acid hydrolase, mitochondrial", "aln": "MLQLLKSSWVRSAGSGVVTWRASAGLF---CPGTRQASDTSDTLHHPSPSSESQVQPVRV--CSMMHLPLQSSPEGLDAAFVGVPLDTGTSNRPGARFGPRRIREESLMLGTVNPSTGALPFQSLRVADLGNVNVNLYNLQDSCRLIREAYQNILATGCIPLTLGGDHTITYPILQAVAKEHGPVGLVHVGAHSNTSDKPLEDKVYHRTPFRRSVDEGLLDSKRVVQIGIRGSSRTLDPYRYSRSQGFRVVLAEDCWMKSLVPLMAEIRQQMGGVPLYISFAIDALDPAYAPGTGTPEIAGLTPSQALEIIRGCQGLNVVGCDLVEVSPPYDLSGNTALLAANLLFEMLCALPKVTTV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BSE5-1", "uniprot_id": "GDAH_HUMAN", "id": "Q9BSE5-1", "name": "Guanidino acid hydrolase, mitochondrial", "aln": "MLRLLASGCARGPGPGVG-ARPAAGLF---HPGRRQSRQASDAPRNQPPSPEFVARPVGV--CSMMRLPVQTSPEGLDAAFIGVPLDTGTSNRPGARFGPRRIREESVMLGTVNPSTGALPFQSLMVADLGDVNVNLYNLQDSCRRIQEAYEKIVAAGCIPLTLGGDHTITYPILQAMAKKHGPVGLLHVDAHTDTTDKALGEKLYHGAPFRRCVDEGLLDCKRVVQIGIRGSSTTLDPYRYNRSQGFRVVLAEDCWMKSLVPLMGEVRQQMGGKPIYISFDIDALDPAYAPGTGTPEIAGLTPSQALEIIRGCQGLNVMGCDLVEVSPPYDLSGNTALLAANLLFEMLCALPKVTTV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:** *. .*. *.** *.:**** ** **: :**: :: .**.* .:** * ****:**:*:*********:****************** ******:***:************* *****:************ *:***::::*:**********:*********:**:******:**.**::*:**. :*:** :****.*******.************ *******.**********************.*:****** *:**** *************************************:**************************************", "identical_positions": 280, "similar_positions": 48, "identity": "78.21%" }, { "cls_id": "homologset.agr.RGD:1308426", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "F1M9C9-1", "uniprot_id": "F1M9C9_RAT", "id": "F1M9C9-1", "name": "histidine--tRNA ligase", "aln": "-----------MPHLGPLRCRTWAALLGQLLRPPR---TVCNRAVGCHSQVAKAVLTSEQLKPHQQ-----------------------------KPNFIIKVPKGTRDLSPQQMVVREKILDKIISCFKRHGAKGLDTPAFELKEMLTEKYEDNFGLMYDLEDQGGELLSLRYDLTVPFARYLAMNKLKRMKRYQVGKVWRRESPAIVQGRYREFCQCDFDIAGEFDPMIPDAECLRIMCEILSGLQLGDFLIKVNDRRVVDGMFAVCGVPESKFRTICSSMDKLDKMSWEDVRLEMVAGKGLAPEVADRIGDYVQCHGGISLVEELFK-DPRLSQSQLALQGLGDLKLLFEYLRLFGIADKISLDLSLARGLDYYTGVIYEAVL-----------LESPAQAGK-------ETLNVGSVAAGGRYDRLVAQFDP----KGHSVPCVGLSIGVERIFYLVEQKMKISCEKVRTTETQVFVATPQ-----KNFLQERLKIIAQLWDAGIKAEMLYKNNPKLLTQLHYCEKEDIPLMVIIGEQEQNEGVVKLR----SVASREEVTVNRESLVAEIQKRLSES---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99KK9-1", "uniprot_id": "SYHM_MOUSE", "id": "Q99KK9-1", "name": "Histidine--tRNA ligase, mitochondrial", "aln": "-----------MPHLGPLRRRAWAALLGQLLRPPS---TVCTR--GCHSQVAKAVLTSEQLKSHQE-----------------------------KPNFVIKVPKGTRDLSPQQMVVREKILDKIISCFKRHGAKGLDTPAFELKEMLTEKYEDNFGLMYDLKDQGGELLSLRYDLTVPFARYLAMNKLKKMKRYQVGKVWRRESPAIAQGRYREFCQCDFDIAGEFDPMIPDAECLRIMCEILSGLQLGDFLIKVNDRRVVDGIFAVCGVPESKLRTICSSMDKLDKMSWEGVRHEMVAKKGLAPEVADRIGDFVQYHGGISLVEDLFK-DPRLSQSQLALQGLGDLKLLFEYLRLFGIADKISLDLSLARGLDYYTGVIYEAVL-----------LESPAQAGK-------ETLSVGSVAAGGRYDNLVAQFDP----KGHHVPCVGLSIGVERIFYLVEQKMKMSGEKVRTTETQVFVATPQ-----KNFLQERLKIIAELWDAGIKAEMLYKNNPKLLTQLHYCEKADIPLMVIIGEQERNEGVIKLR----SVASREEVTINRESLVAEIQKRLSES---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49590-1", "uniprot_id": "SYHM_HUMAN", "id": "P49590-1", "name": "Histidine--tRNA ligase, mitochondrial", "aln": "-----------MPLLGLLPRRAWASLLSQLLRPPC---ASCTGAVRCQSQVAEAVLTS-QLKAHQE-----------------------------KPNFIIKTPKGTRDLSPQHMVVREKILDLVISCFKRHGAKGMDTPAFELKETLTEKYGEDSGLMYDLKDQGGELLSLRYDLTVPFARYLAMNKVKKMKRYHVGKVWRRESPTIVQGRYREFCQCDFDIAGQFDPMIPDAECLKIMCEILSGLQLGDFLIKVNDRRIVDGMFAVCGVPESKFRAICSSIDKLDKMAWKDVRHEMVVKKGLAPEVADRIGDYVQCHGGVSLVEQMFQ-DPRLSQNKQALEGLGDLKLLFEYLTLFGIADKISFDLSLARGLDYYTGVIYEAVL-----------LQTPTQAGE-------EPLNVGSVAAGGRYDGLVGMFDP----KGHKVPCVGLSIGVERIFYIVEQRMKTKGEKVRTTETQVFVATPQ-----KNFLQERLKLIAELWDSGIKAEMLYKNNPKLLTQLHYCESTGIPLVVIIGEQELKEGVIKIR----SVASREEVAIKRENFVAEIQKRLSES---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8IQX8-1", "uniprot_id": "Q8IQX8_DROME", "id": "Q8IQX8-1", "name": "histidine--tRNA ligase", "aln": "MSDTREQILEQIKVQGDLVRQLKAAKESKEKTAPSGGGRVSSSGVPAQRQQQQQPQKQQQAQVQQQQHEQLHQIDEEVARLLALKATLGGDAAPTNQKFTLKTPKGTRDYGPQQMTLRQGVLDKIVQVFKRHGGEAIDTPVFELKEVLTGKYGEDSKLIYDLKDQGGEILSMRYDLTVPLARYLAMNKISSIKRYHIAKVYRRDNPAMTKGRYREFYQCDFDIAGTYDPMLPDAECVKIVSEILDTLDIGDYVIKLNHRQLLDGMFQACGVPADSFRTICSAVDKLDKSPWADVRKEMVDEKGLDEAAADRIGEYVRLSGGAELVEQLLA-NEKLKAVPNAVKGLEGMKQLLKYCSIFGLDKRVSFDLSLARGLDYYTGVIYEGVLKGES-----ATVASPAKTSQQNGEQANEPATVGSVAGGGRYDNLVGMFDP----RGKAVPCVGVSIGVERIFSVLEARAAASGLKLRTSDVEVYVASAH-----KGLHEQRLKVLNLLWDAGVKAEHSYKLNPKLLVQLQHCEEHQIPLVVVLGDAELAQGLVKLR----EVTTREETNVKLEDLAAEIRRRQQASA--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P07263-1", "uniprot_id": "SYH_YEAST", "id": "P07263-1", "name": "Histidine--tRNA ligase, mitochondrial", "aln": "------------MLSRSLNKVVTSIKSSSIIRMSS----ATAAATSAPTANAANALKASKAPKKGK------------------------------LQVSLKTPKGTKDWADSDMVIREAIFSTLSGLFKKHGGVTIDTPVFELREILAGKYGEDSKLIYNLEDQGGELCSLRYDLTVPFARYVAMNNIQSIKRYHIAKVYRRDQPAMTKGRMREFYQCDFDVAGTFESMVPDSECLSILVEGLTSLGIKDFKIKLNHRKILDGIFQIAGVKDEDVRKISSAVDKLDKSPWEAVKKEMTEEKGQSEETADKIGEYVKLNGSLKEIHAVLSADANITSNEKAKQGLDDIATLMKYTEAFDIDSFISFDLSLARGLDYYTGLIYEVVTSASAPPENASELKKKAKSAEDAS----EFVGVGSIAAGGRYDNLVNMFSEASGKKSTQIPCVGISFGVERIFSLIKQRINSS-TTIKPTATQVFVMAFGGGKDWTGYLPERMKVTKQLWDAGIEAEYVYKAKANPRKQFDAAEKAGCHIAVILGKEEYLEGKLRVKRLGQEFADDDGELVSAADIVPIVQEKLSQIHEDGLNEVTRLIKGL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : .. . . . : : : :. :*.****:* . ..*.:*: ::. : **:**. :***.***:* *: ** :: *:*:*:*****: *:*******:***:***::. :***::.**:**:.*::.:** *** *****:** ::.*:**:**: *: * * * : *: **:*.*:::**:* .** ...* *.*::***** .* *: **. ** .**:**::*: *. . :. :: : .:. * :** .: *::* *.: . :*:*************:*** * : . :::.: * ***:*.***** ** *. :. :****:*:****** ::: : . .::.: .:*:* : .. :*:*: ***:*::** ** :.: *:. .*. : *::*. * :* :::: ..: : :. .:.. ::.: . ", "identical_positions": 170, "similar_positions": 173, "identity": "28.48%" }, { "cls_id": "homologset.agr.RGD:1308428", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8J8XFB5-1", "uniprot_id": "A0A8J8XFB5_RAT", "id": "A0A8J8XFB5-1", "name": "", "aln": "MYCCSAQDSKMDYKRRFLLGGSKQKVQQHQQYPMPELGRALSAPLASTAPSAPLGSLTTAGSCHHAMPHSTPIADIQQGISKYLDALNVFCRASTFLTDLFSTVFRNSHYSKAAMQLKDVQEHVMEAASRLTSAIKPEIAKMLMELSAGAANFTDQKEFSLQDIEVLGRCFLTVVQVHFQFLTHALQKVQPVAHSCFAEVVVPEKKNSSS---LSGMGHTPELEEAVRSWRGAAEATSRLRERGCDGRLAGIEVQQLFCSQSAAIPEHQLKELNLKIDSALQAYKIALESLGHCEYAMKAGFHLNPKAIEASLQGCCSEAEAQQTGRRQTPPQPMQCELPTVPVQIGSHFLKGVSFNESAADNLKLKTHTMFQLIKEAGCYDGITPRDDLPVTEVLNQVCPSTWRGACKTAVQLLFGQAGLVVVDTAQIENKEAYAPQISLEGSRIVVQVPSTWCLKEDPATMSLLQRSLDPEKTLGLVDVLYTAVLDLNRWRTGREQALPCIQIQLQRDICDFGNQADLPSGNGSKSSG-LQKTFSKLTSRFTKKVSCTNSGS-THY------SKTIFTAGCSEEKAKMLGSNIDTRLQSILNIGNFPRTTDPSQSSQNSRNPMVNGFLLERRENFLHGDDGKDEKGMNLPTDQEMQEVIDFLSGFNMGQSHQGSPLVTRRNSTATAMVTEQKTGTMQPQQPSLPLAPPLRPPQAGAHTPLAAQQGLAPQQQSPKQQQPQVQFYQHLLQPIGSQQTPPQSRAPGKWGHGSSQHPSQPMAAGLSPLGQWPGISDLSSDLYSLGLVSSYMDNMMSEVLGQKPQGPRNNTWPNRDQSDGVFGMLGEILPFDPAVGSDPEFARYVAGVSQAMQQKRQAQHGRRPGNPRGNWPPMDDAHRTWPLPEFFTEGDSLHSGWSGAQGDSASSSDETSSANGDSLFSMFSGPDLVAAVKQRRKHSSGEQETSTLPSPPLLTTVEDVNQDNKTKTWPPKAPWQHPSPLPSTLPSPAAPLYAVASPGSQWNDTMQMLQSPVWAAASDCNTTSFTYVQTPPQPPPPPAHKAAPKGFKAFPGKAERRPAYLPQY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O15063-1", "uniprot_id": "GRRE1_HUMAN", "id": "O15063-1", "name": "Granule associated Rac and RHOG effector protein 1", "aln": "MYCCSAQDSKMDYKRRFLLGGSKQKVQQHQQYPMPELGRALSAPLASTATTAPLGSLTAAGSCHHAMPHTTPIADIQQGISKYLDALNVFCRASTFLTDLFSTVFRNSHYSKAATQLKDVQEHVMEAASRLTSAIKPEIAKMLMELSAGAANFTDQKEFSLQDIEVLGRCFLTVVQVHFQFLTHALQKVQPVAHSCFAEVIVPEKKNSGSGGGLSGMGHTPEVEEAVRSWRGAAEATSRLRERGCDGCLAGIEVQQLFCSQSAAIPEHQLKELNIKIDSALQAYKIALESLGHCEYAMKAGFHLNPKAIEASLQGCCSEAEAQQTGRRQTPPQPMQCELPTVPVQIGSHFLKGVSFNESAADNLKLKTHTMLQLMKEAGCYNGITSRDDFPVTEVLNQVCPSTWRGACKTAVQLLFGQAGLVVVDTAQIENKEAYAPQISLEGSRIVVQVPSTWCLKEDPATMSLLQRSLDPEKTLGLVDVLYTAVLDLNRWRAGREQALPCIQIQLQREICDFGNQADLPSGNGNKSSGGLQKTFSKLTSRFTKKASCTSSSSSTNYSIQNTPSKNIFIAGCSEEKAKMPG-NIDTRLQSILNIGNFPRTTDPSQSAQNSSNTVANGFLMERRENFLHGDDGKDEKGMNLPTDQEMQEVIDFLSGFNMGQSHQGSPLVTRHNSAATAMVTEQKAGAMQPQQPSLPVPPPPRAPQAGAHTPLTPQPGLAPQQQSPKQQQPQVQYYQHLLQPIGPQQPPPQPRAPGKWVHGSSQQPAQAVGAGLSPLGQWPGISDLSSDLYSLGLVSSYMDNVMSEVLGQKPQGPRNNTWPNRDQSDGVFGMLGEILPFDPAVGSDPEFARYVAGVSQAMQQKRQAQHGRRPGNPRGNWPPMDDAHRTWPFPEFFTEGDGLHGGWSGAQGDSASSSDETSSANGDSLFSMFSGPDLVAAVKQRRKHSSGEQDTSTLPSPPLLTTVEDVNQDNKTKTWPPKAPWQHPSPLPSTLPSPSAPLYAVTSPGSQWNDTMQMLQSPVWAATNDCSAAAFSYVQTPPQPPPPPAHKAAPKGFKAFPGKGERRPAYLPQY", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*************************************************.:*******:**********:******************************************** *************************************************************************************:*******.* *********:************************ **************************:************************************************************************************************:**:******:***.***:*******************************************************************************************************:***************:***************.**** ***************.***.*.* *:* **.** ********** * ************************:*** *.:.****:**************************************************:**:*********:*:*********:.** *.*********:.* *****************:*********.**.***.****** *****:*:*.:.*******************************:***************************************************************************************:********.**.************************************************:********************************************:******:********************:.**.:::*:***************************.**********", "identical_positions": 992, "similar_positions": 59, "identity": "92.62%" }, { "cls_id": "homologset.agr.RGD:1308429", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZU78-1", "uniprot_id": "A0A8I5ZU78_RAT", "id": "A0A8I5ZU78-1", "name": "leucine--tRNA ligase", "aln": "MASACQRLSFCVSPLKRQLVSGLPVILWER-IIPGCSRSIYSATGKWTKEYTLQTRKDVEKWWHQQIKVQASKISEEDKLKPKFYLLSMFPYPSGKLHMGHVRVYTLSDTIARFQKMRGMQVINPMGWDAFGLPAENAAIERNLHPESWTQSNIKHMRKQLDRLGLCFSWDREITTCLPDYYKWTQYLFIKLYEAGLAYQKEALVNWDPVDQTVLANEQVNEYGCSWRSGAKVEKKYLRQWFIKTTAYAKAMQDALAD--LPEWYG-IKEMQAHWIGDCVGCHLDFTLKVDGQDTGEKLTAYTATPEAIYGISHVAISPSHGLLHGCSSLKTALQKALVPGR---------DCLTPVMAVNMLTLQEVPVVIMAKPDLEG--SLDSKIGIPSTSSEDTRLAQA--LGLPYSEVIETSPDGTERLS----------------------GSAEFTGMTRQDAFVALTRKARGMRVGGHVTSNKLKDWLVSRQRYWGTPIPIVHCPACGPVPVPLQDLPVTLPSITSLTGRGGSPLASALEWVNCSCPRCKG-SAKRETDTMDTFVDSAWYYFRYTDPHNTHSPFSSALADFWMPVDLYIGGKEHAVMHLFYARFFSHFCHRQKMVKHR----EPFHKLLAQGLIKGQTFHLL-SGQCLKREDIDFTGP-----TPVCAKTKERLEVTWEKMSKSKHNGVDPEEIVAQYGIDTIRLYILFAAPPEKDILWDVKTDALPGVLRWQQRLWSLTTRFIEARTSGTAPQPQLLNNKEKAKARSLWEYKNAVITQVTTHFTEDFALNSVVSQLMGLSGALSQASQRLVLHSPEFEDALCALLVMAAPLAPHITSELWAGLALVPSKL---CDRYAWDAGVMLQAWPTVDSQF-----LQKPDMVQMAVLINNKACGKIPVP--QHVAQDQDKVHEFVLQSEL---------GIKLLQGRSIRKAFLSPRTALINFLVKE---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VDC0-1", "uniprot_id": "SYLM_MOUSE", "id": "Q8VDC0-1", "name": "Probable leucine--tRNA ligase, mitochondrial", "aln": "MASTCQRLSFYVSPLKRQLVSRPPVILWER-LIPGCSRSIYSATGKWTKEYTLQTRKDVEKWWHQQIKEQASRVSEEDKLKPKFYLLSMFPYPSGKLHMGHVRVYTLSDTIARFQKMRGMQVINPMGWDAFGLPAENAAIERNLHPESWTQSNIKHMRKQLDRLGLCFSWDREITTCLPDYYKWTQYLFIKLYEAGLAYQKEALVNWDPVDQTVLANEQVNEYGCSWRSGAKVEKKYLRQWFIKTTAYAKAMQDALAD--LPEWYG-IKGMQAHWIGDCVGCHLDFTLKVDGEDTGEKLTAYTATPEAIYGISHVAISPSHGLLHGCSSVKKALQKALVPGR---------DCLTPVMAVSMLTLQEVPIVIMANPDLEG--SLDSKIGIPSTSSEDTRLAQA--LGLPYSEVIEASPDGTERLS----------------------GSAEFTGMTRQDAFVALTRKARGMRVGGHVTSNKLKDWLISRQRYWGTPIPIVHCPACGPVPVPLQDLPVILPSIASLTGRGGSPLATALEWVNCSCPRCKG-SAKRETDTMDTFVDSAWYYFRYTDPHNTQSPFGSALADFWMPVDLYIGGKEHAVMHLFYARFLSHFCHDQKMVKHR----EPFHKLLAQGLIKGQTFRLP-SGQCLKKEDIDFTGP-----APVCAKTKEKLEVTWEKMSKSKHNGVDPEEIVAQYGIDTIRLYILFAAPPEKDILWDVKTDALPGVLRWQQRLWSLTTRFIEARTSGTVPQPQLLNSKEKTKAQNLWEYKNAVIAQVTTHFTEDFALNSVVSQLMGLSSALSQASQRVVLHSPEFEDALCALLVMAAPLAPHVTSELWAGLTLVPSKL---CDHYAWDSGVMLQAWPTVDSQF-----LQKPDMVQMAVLINNKACGKIPVP--QHVAQDQDKVHELVLQSEL---------GMKLLQGRSIKKAFLSPRTALINFLVQE---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15031-1", "uniprot_id": "SYLM_HUMAN", "id": "Q15031-1", "name": "Leucine--tRNA ligase, mitochondrial", "aln": "MASVWQRLGFYASLLKRQLNGGPDVIKWERRVIPGCTRSIYSATGKWTKEYTLQTRKDVEKWWHQRIKEQASKISEADKSKPKFYVLSMFPYPSGKLHMGHVRVYTISDTIARFQKMRGMQVINPMGWDAFGLPAENAAVERNLHPQSWTQSNIKHMRKQLDRLGLCFSWDREITTCLPDYYKWTQYLFIKLYEAGLAYQKEALVNWDPVDQTVLANEQVDEHGCSWRSGAKVEQKYLRQWFIKTTAYAKAMQDALAD--LPEWYG-IKGMQAHWIGDCVGCHLDFTLKVHGQATGEKLTAYTATPEAIYGTSHVAISPSHRLLHGHSSLKEALRMALVPGK---------DCLTPVMAVNMLTQQEVPVVILAKADLEG--SLDSKIGIPSTSSEDTILAQT--LGLAYSEVIETLPDGTERLS----------------------SSAEFTGMTRQDAFLALTQKARGKRVGGDVTSDKLKDWLISRQRYWGTPIPIVHCPVCGPTPVPLEDLPVTLPNIASFTGKGGPPLAMASEWVNCSCPRCKG-AAKRETDTMDTFVDSAWYYFRYTDPHNPHSPFNTAVADYWMPVDLYIGGKEHAVMHLFYARFFSHFCHDQKMVKHR----EPFHKLLAQGLIKGQTFRLP-SGQYLQREEVDLTGS-----VPVHAKTKEKLEVTWEKMSKSKHNGVDPEEVVEQYGIDTIRLYILFAAPPEKDILWDVKTDALPGVLRWQQRLWTLTTRFIEARASGKSPQPQLLSNKEKAEARKLWEYKNSVISQVTTHFTEDFSLNSAISQLMGLSNALSQASQSVILHSPEFEDALCALMVMAAPLAPHVTSEIWAGLALVPRKL---CAHYTWDASVLLQAWPAVDPEF-----LQQPEVVQMAVLINNKACGKIPVP--QQVARDQDKVHEFVLQSEL---------GVRLLQGRSIKKSFLSPRTALINFLVQD---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VZ82-1", "uniprot_id": "Q9VZ82_DROME", "id": "Q9VZ82-1", "name": "leucine--tRNA ligase", "aln": "MQALRRTRPWGAVYWN----------SWRRLLTQSCTR-------NDNPELTSDVKHRIEAHWREQLSGGQFNPKDS---QDKYYVLSMFPYPSGNLHMGHVRVYTIADSVARFQRMCGKNVFQPMGWDSFGLPAENAANQRGVEPASWTEQNIAQMKEQLKRLGCSFDWNHELSTCSPKYYKWTQHLFLMLHRHGLAYQNEALVNWDPVDKTVLADEQVDANGCSWRSGAKVEKKLLRQWFIRTSAYAKQLLDGLEDPTLRDWRD-IINLQRHWIGECDGYAFNLLTSASG-----LLRVWTTHPEHLKDP------------HAFLVLRSNHHLSKLKGA---------DSLS---AANPFAGTTMPVVFSDEVTFPP--KSDVYLAAPSFRGEDKDLWDS--YGLAFTS------NGKDEES----------------------LSPANWEMLRKEVLQAATR----LNVGGYRVSSKLKDWLISRQRYWGTPIPIVHCQKCGAVPVPEEQLPVSLP-----------PKDSPKEAFLCDCPKCGEKDARRETDTMDTFVDSSWYYLRYLDAQNSERIFDTALTKKFMPVDLYIGGKEHAVLHLYYARFINHFLHSCGLSPTS----EPFSRLLVQGMVMGRSFRVKGSGRYVPETEVEIVNAKK--NQAVLKETKEPVVMTWEKMSKSKLNGVEPSDMFNEYGTDTTRLIILADVAPTSHRNWSSAT--FPGILNWQKRLWLTLQDFQQAREDQTASDVVPTSEEFLAEDAKLFDARNFYVKGATFNYRHAQQLSVAISKMQGLTNSLRRTPKHVLRHGKQFERALAAQIIMLAPMAPHFASELWSKFVAIPGRLNPASQELQWSEDVLAQRWPDIDPAYNLDLSIKVNGFENCVIKVQRTHLDKVTHSDALDIAFNTESVTSYLIDKKIRTTNFVLYPGIEAILNIYVDKAKMKQKPPTTDDAEAQPQA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P11325-1", "uniprot_id": "SYLM_YEAST", "id": "P11325-1", "name": "Leucine--tRNA ligase, mitochondrial", "aln": "MLSRPSSRFLST---------------------------------KRGPGPAVKKLIAIGEKWKQKTTRG--LPKQDTLNSGSKYILCQFPYPSGALHIGHLRVYVISDSLNRFYKQKGYNVIHPMGWDAFGLPAENAAIERSINPAIWTRDNIAKMKQQMQSMLANFDWDREITTCDPEYYKFTQWIFLKLFENGLAYRKEAEINWDPVDMTVLANEQVDAQGRSWRSGAIVEKKQLKQWFLGITKFAPKLKKHLNQ--LKDWPSNVKQMQKNWIGESVGAELVFKVADPKFEN---LIVFTTRPETLFAVQYVALALDHPIVQKYCEEMPDLKEFIQKSDQLPNDTKEGFQLPNIKAVNPLTKEEVPIFAAPYVVSSYGSAPSAVMGCPGHDNRDFEFWQTNCPGEHIKTCIAPFFDDASKVTEQERQRIIDTVPFTSTDGVLTKECGEHSGVLTVVARKSIMGMLNSEGLSKSVVRYKIRDWLISRQRYWGTPIPIIHCDNCGPVPVPESDLPVKLPELEGLDTKG-NPLSTIDEFVNVACPSCGS-PAKRETDTMDTFIDSSWYYFRFLDPKNTSKPFDREIASKNMPVDIYIGGVEHAILHLLYSRFIAKFLGSINAWSDPAGIFEPFKKLVTQGMVQGKTYVDPDSGKFLKPDELTFVNDSPDGNTVIIKSNGKVPVVSYEKMSKSKYNGADPNECILRHGPDATRAHILFQSPIADALNWDESK--IVGIERWLQKVLHLTKNILSLEKDLAISKDYKTPTDLNDAEVKFHNDFQRFLKSITESFEVNLSLNTVISDYMKLTNILESALKKGEVRNEMIVQNLQKLVTVIYPAVPSISEEAAEMINSQMEWN--------------QYRWPEVERTT-------ESKFKKFQIVVN-GRVKFMYTADKNFLKLGRDAVIETLMNLPE---------GRMYLMNKKIKKFVMKFN--VISFLFHK---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : . : : . : *::: . .: . . *:*. ****** **:**:***.::*:: ** : * :*::*****:********* :*.:.* **..** :*::*:. : *.*::*::** *.***:** :*: *.. ****::** :****** ****:***: * ****** **:* *:***: : :* : . * : * :* . : :* :***:. * : : * .:*: ** : : : . *. *.. :: :*:. . :. *. ..* : :: * . :. .. : . : . : :. . *::***:************:** **..*** .:*** ** * * . ** * *:*********:**:***:*: *.:*. *. ::. ****:**** ***::** *:**: :* *** :*:.**:: *::: **: : :: :.. : .. : :::******* **.:*.: . .:* *: * ** . . *. . : *: .* ::: : . . . .. . .: : : : * : *. .:*. *:. * : : :. : * : : * .* .:.* : ** :: . : : :: : . : . : * . ::: * : . : * :. . . . ", "identical_positions": 219, "similar_positions": 232, "identity": "22.48%" }, { "cls_id": "homologset.agr.RGD:1308432", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z9C0-1", "uniprot_id": "D3Z9C0_RAT", "id": "D3Z9C0-1", "name": "GATOR2 complex protein MIOS", "aln": "-MSGTKPDILWAPHQVDRFVVCD---SELSLYHVESAVNSEL-------------------------------KAGSLRLSEDSAATLLSINSDTPYMKCVAWYLNYDPECLLAVGQANGRVVLTSLGQDHNSKFKDLIGKEFVPKHARQCNTLAWNPLDSNWLAAGLDKHRADFSVLIWDICSKYTPDIVPMEKVRLSAGEAETTLLVTKPLYELGQNDACLSLCWLPRD-QKLLLAGMHRNLAIFDLRN-TSQKMFVNTKAVQGVTVDPYFHDRVASFYEG-QVAIWDLR-----------KFEKPVLTLTEQPKPLTK--------VAWCPTRTGLLATLTRDSNIIRL---YDMQHTPTPIGDETEPTIIERSVQPCDN-------YIASFAWHPTSQN--RMIVVTPNRTMSDFTVFERISLAWSPITSLMWACGRHLYECAEEE-----------------------------------------------------------------------SDNTLEKDIATKMRLRALSRYGLDTEQ--VWRNHILAGNEDPQLKSLWYTLHLLMKQYTEEMDQKSPGNKGSLVYAGIKS---------------------IVKSSLGMVESSRHNWSG-LDKQTDIQNLN-EERILALQLCGWIKKGTDVDVGPFLNSLVQEGEWERAAAVALFNLDIRRAIQILNEGASSEKGDLNLNVVAMALSGYTDEKNS-LWREMCSTLRLQLNNPYLCVMFAFLTSEAGAYDGVLYENKVAVRDRVAFACKFLGDAQLNKYIEKLTNEMKEAGNLEGILLTGLTKDGVDLMESYVDRTGDVQTASYCMLQGSPLDVLKDERVQYWIENYRNLLDAWRFWHKRAEFDIHRSKLDPSSK-------PLAQVFVSCNFCGKSISYSCSSVP------------------HQGRGFSQYGVSGSPTKSKVTS------CPGCRKPLPRCALCLINMGT---PVSSCPGGSKSDEKVDLSKD-------KKLAQFNNWFTWCHNCRHGGHAGHMLSWFRDHAECPVSACTCKCMQLDTTGNLVPAETLQP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VE19-1", "uniprot_id": "MIOS_MOUSE", "id": "Q8VE19-1", "name": "GATOR2 complex protein MIOS", "aln": "-MSGTKPDILWAPHQVDRFVVCD---SELSLYHVESAVNSEL-------------------------------KAGSLRLSEDSAATLLSINSDTPYMKCVAWYLNYDPECLLAVGQANGRVVLTSLGQDHNSKFKDLIGKEFVPKHARQCNTLAWNPLDSNWLAAGLDKHRADFSVLIWDICSKYTPDIVPMEKVRLSAGEAETTLLVTKPLYELGQNDASLSLCWLPRD-QKLLLAGMHRNLAIFDLRN-TSQKMFVNTKAVQGVTVDPYFHDRVASFYEG-QVAIWDLR-----------KFEKPVLTLTEQPKPLTK--------VAWCPTRTGLLATLTRDSNIIRL---YDMQHTPTPIGDETEPTIIERSVQPCDN-------YIASFAWHPTSQN--RMIVVTPNRTMSDFTVFERISLAWSPITSLMWACGRHLYECAEEE-----------------------------------------------------------------------SDNSLEKDIATKMRLRALSRYGLDTEQ--VWRNHILAGNEDPQLKSLWYTLH-FMKQYTEDNDQKSPGNKGSLVYAGIKS---------------------IVKSSLGMVESSRHNWSG-LDKQTDIQNLN-EERILALQLCGWIKKGTDVDVGPFLNSLVQEGEWERAAAVALFNLDIRRAIQILNEGASSEKGDLNLNVVAMALSGYTDEKNS-LWREMCSTLRLQLNNPYLCVMFAFLTSEAGAYDGVLYENKVAVRDRVAFACKFLGDAQLNKYIEKLTNEMKEAGNLEGILLTGLTKDGVDLMESYVDRTGDVQTASYCMLQGSPLDVLKDERVQYWIENYRNLLDAWRFWHKRAEFDIHRSKLDPSSK-------PLAQVFVSCNFCGKSISYSCSSVP------------------HQGRGFSQYGVSGSPTKSKVTS------CPGCRKPLPRCALCLINMGT---PVSSCPGGSKSDEKVDLSKD-------KKLAQFNNWFTWCHNCRHGGHAGHMLSWFRDHAECPVSACTCKCMQLDTTGNLVPAETVQP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NXC5-1", "uniprot_id": "MIOS_HUMAN", "id": "Q9NXC5-1", "name": "GATOR2 complex protein MIOS", "aln": "-MSGTKPDILWAPHHVDRFVVCD---SELSLYHVESTVNSEL-------------------------------KAGSLRLSEDSAATLLSINSDTPYMKCVAWYLNYDPECLLAVGQANGRVVLTSLGQDHNSKFKDLIGKEFVPKHARQCNTLAWNPLDSNWLAAGLDKHRADFSVLIWDICSKYTPDIVPMEKVKLSAGETETTLLVTKPLYELGQNDACLSLCWLPRD-QKLLLAGMHRNLAIFDLRN-TSQKMFVNTKAVQGVTVDPYFHDRVASFYEG-QVAIWDLR-----------KFEKPVLTLTEQPKPLTK--------VAWCPTRTGLLATLTRDSNIIRL---YDMQHTPTPIGDETEPTIIERSVQPCDN-------YIASFAWHPTSQN--RMIVVTPNRTMSDFTVFERISLAWSPITSLMWACGRHLYECTEEE-----------------------------------------------------------------------NDNSLEKDIATKMRLRALSRYGLDTEQ--VWRNHILAGNEDPQLKSLWYTLH-FMKQYTEDMDQKSPGNKGSLVYAGIKS---------------------IVKSSLGMVESSRHNWSG-LDKQSDIQNLN-EERILALQLCGWIKKGTDVDVGPFLNSLVQEGEWERAAAVALFNLDIRRAIQILNEGASSEKGDLNLNVVAMALSGYTDEKNS-LWREMCSTLRLQLNNPYLCVMFAFLTSETGSYDGVLYENKVAVRDRVAFACKFLSDTQLNRYIEKLTNEMKEAGNLEGILLTGLTKDGVDLMESYVDRTGDVQTASYCMLQGSPLDVLKDERVQYWIENYRNLLDAWRFWHKRAEFDIHRSKLDPSSK-------PLAQVFVSCNFCGKSISYSCSAVP------------------HQGRGFSQYGVSGSPTKSKVTS------CPGCRKPLPRCALCLINMGT---PVSSCPGGTKSDEKVDLSKD-------KKLAQFNNWFTWCHNCRHGGHAGHMLSWFRDHAECPVSACTCKCMQLDTTGNLVPAETVQP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q802U2-1", "uniprot_id": "MIOS_DANRE", "id": "Q802U2-1", "name": "GATOR2 complex protein MIOS", "aln": "MSSGYKPDILWSPHHADRYVICD---TELSLYRIGPSGSSET-------------------------------KAGALQLSEETAATLLAINSDTPFMKCVAWYPKHEPECLLAVGHTNGRVVLTSLGQSHNSKSKDLAGKEFVPKHARQCNTLAWNPVDSNWLAAGLDKHRADFSVLIWDISSKFSPEAVPAEKVRLSG-DADSGLLVTKPLYELGQNDACLSLCWLPRDHQKLLLAGMHRNLAIFDLRN-TSQKTFVNTKAIQGVTVDPHFQDRVASYFEG-QVAIWDLR-----------KFEKPVFTLNEQPKPLTK--------VAWCPTRMGLLATLTRDSNIIRL---YDMQHTPMPFGDEVEPTIMERGVQPCSES------IISSFAWHPSAQN--RMVVVSPSRVMNDFTLFERISLAWSSTTSLMWACGRHLYECAEDSG----------------------------------------------------------------------QAAEAEKDIATKMRERAQSRYGHDTVQ--VWRNHVLAGGDDPQLRSLWYTLH-FMKQYTENVEQKQQSNKQSLIYSGIKN---------------------IVKSSSGTTET-RRCWSG-SDRQTDVPRFHSEERSLALQLCGWISQGPDTDVEPFLKSLEQEGEWERAAAVALFNLDIRRAIQILNKGASSEKGDLNLNVVAMALSGYTDEKNS-LWREMCSSLRLQLKKPYLCIMFAFLTSEPGAYDGVLYESRVAVRDRVAFACMFLNDAQLPRYIDKLTNEMKEAGNLEGILLTGLTKDGVDLMESYVDRTGDVQTASFCMLKGSPGEVLKDPRVQCWIENYRNLLDAWRFWHKRAEFDIHRSKLDPSSK-------PLAQVFVSCNFCGKSISYSCSAMP------------------HQGRGFSQYGVSGSPTKSKVTS------CPGCRKPLPRCALCLMNMGT---PVSSCPGTGKADEKADLTRD-------KKLAQFNNWFTWCHNCRHGGHAGHMLSWFRDHSECPVSACTCKCMQLDTTGNLVPSDSV--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VQ89-1", "uniprot_id": "MIO_DROME", "id": "Q9VQ89-1", "name": "GATOR2 complex protein Mio", "aln": "-MSGNTHGLSWFPHFPDKFVSWG---QEIHLYEVRRKDDHSQ-------------------------------KSRLPYISVN----YLANESRYQYARCVAASYHSD-QPIIAVGLADGKVGICNFRDTYDS------SWEYTPRQQRMCTCLAWNELDANILAIGHDRHRNDTCITIWDIERGVP----------------------KETANFFGVGESANSICWDRNH-RTVIAGMSQKMIKLFDLRQSNATCQSIQTKTVQGLSVSP-NGNYLCSYVDS-VITLWDPR-----------NIKSPLRQIQ-SSKNHLQ--------IAWCPTRTSLLSSLQRDSSYITL---YDIRSVDTDNSGEIYHVKRQISPFPARYQHSGKFSFVNCLSWHSRDFE--RALLLADALNILDFRLPATLHTAHSNRRKLPLLMQRPLYTPASPTST---------------------------------AATPTQQQPTSSCSTNSGSSLDFSTPGGSPFNVDLLKPELFELDLVDETRQRALEDYGIKPDN--KRFGELHLT---PYLRNVWSTLN---NVYSEDRLTGLKATLG--INLGHTS---------------------EALMASSRIESQVLQWPEGINNSNKLICYRSEQRDLALQLCGWA---FEQELDRFIDQLYANKEYSRAAMICVFHLKIFHACNILSSAADNMRDPSMYRITVIALSSFNADRCSSTWRNQRSSANMQIHDPHLRAVFSFLTMEKDNFDAVLKEEGVSLSDRMAFACKYLSETKLADYVAQQIQAAIDGGDLNGLLLTGESQDGIDILQSYMDTSFDVQTVALVAINYFRQELFEDKRIQYWIASYLDHLNSWGLWEKRAELDIKIESIRPSSR-------SSRTVFLSCNFCGKSVSNALLDEP------------------RPR--------STTTSTNRLSS------CPSCRKPLPRCSLCLMHMGT---MVNMSNG--ETPTTTPDVPG-------WQTKPFSKWFSWCQTCRHGGHTEHIMQWFKQNSECPVSSCNCRCFDMDGTKPNTLRDIS--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38164-1", "uniprot_id": "SEA4_YEAST", "id": "P38164-1", "name": "SEH-associated protein 4", "aln": "-MGLIKKVTHWSYDNLIDYLSVNPTRDEVTHYKVDPENESDESIIKLHTVKDFGSITCLDYSESEIGMIGVGEKNGYLRIFNISGQNSSSPASHAPVGLNANNETSMTNASGGKAAQAENIVGSVSNLKDTQGYPVSETNYDIRVRAKKQRCINSLGINTNGLIAMGLDRNKHDSSLQIWDMNYHDDS------------------HETINPMFSYCTNESIVSLKFLNDT---SVLAASTKFLKEIDVRS-PNPIYQHPTRLTYDIKLNPFNDWQFSTYGDDGTLAIWDRRKLSDQASLGDLNVASPLLTFEKLVGSGAASRKYMNSCFRWSCVRNNEFATLHRGDTIKRWRLGYYCDSNRDIAADDDNEMNIENLFVSSVHDTNTMYDRVATFDYIPRSNNGTSLICMRQSGTIYRMPISEVCSKAILNNRNSLLLSNFENTEIDEIRVNNEHEKSNLENVKTILKNLSFEDLDVSEDYFPSGHDEPNNEIEYSELSEEENEGSNDVLDSKRGFELFWKPEKLLEKDISVIMRTRASLGYGLDPMNTVEMIDSSKNLQNNAYIRNTWRWIAIAKASVDDGTMVSGDLDLGYEGVIGIWNGINGISNQDRYRQETILSDKQLNKEMEKIIKLRRKNRDRNSPIANAAGSPKYVQRRLCLIISGWDLS--RSDYEDKYNIIMKNGHYEKAAAWAVFFGDIPKAVEILGSAKKERLR--LIATAIAGYLAYKDLPGNNAWRQQCRKMSSELDDPYLRVIFAFIADN--DWWDILYEPAISLRERLGVALRFLNDTDLTTFLDRTSSTVIENGELEGLILTGITPNGIDLLQSYVNKTSDVQSAALISIFGSP-RYFRDQRVDEWIQTYRDMLKSWELFSMRARFDVLRSKLSRTKTGVLTADIKPRQIYIQCQNCKQNINTPRTSSPSSAVSTSAGNYKNGEAYRRNNADYKKFNTGSSEAQAADEKPRHKYCCPHCGSSFPRCAICLMPLGTSNLPFVINGTQSRDPMQTEDSQDGANRELVSRKLKLNEWFSFCLSCNHGMHAGHAEEWFDRHNVCPTPGCTCQCNK---------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . * . :: . *: *.: . . * : : * . .. ::. * . . :. . : : : : . . :* * *::: * .: ***: :. .:: *: : : . : : :*:*. *: .:.:.* ..:: :. :::** * :. .*: : . *. .* . :::* *... * ..: : .. : : : . : : : : : : * . . * *: * ** ** .. : . . ::. * : : * . : . . :* *.* :.** : . : : .:.:** .:* .* :* :**... .. . . .:. . **: . ::..*:* :*:*:: : : :* * ::: :*:..* :*.::.* :: : . : *:*:*::*** : :*:*:::**:: : ***:.: : :.* *:: ** .* : *.:* :: **.:*: ..: :. :::.*: * :.:. . * : . : : . ** * ..:***::**: :** . . . . : :.:**::* .*.** *: * .** : **...*.*:* . ", "identical_positions": 112, "similar_positions": 251, "identity": "10.34%" }, { "cls_id": "homologset.agr.RGD:1308433", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VJG8-1", "uniprot_id": "Q9VJG8_DROME", "id": "Q9VJG8-1", "name": "", "aln": "----------------MFCALSAFLTFVGVYALSSYLYEQLRTPYKLIKIRYFSGTRP----TLKERFGDWAAVTGASDGIGKEYAKELARQNINVVLIARTEEKLQAVAKEIADCGAGVQTKIVIADFTKGSQVYEHIEKETANIPISILVNNVG--IATPKSLLKYNQEETQNIIDTNVVAVSQLSRIFFQRMKAS--------KLKGAIVNVGSGTELQPLPNGAYYAASKAYTRSLTLALYHEAKPYGIHVQMLSPNFVVTKINSYSRQIMKGGLLIPSASAYAKSAVNQLRD------EVDETPGYLWHHVQNAVATAFT---WRVRTYVACKLFNKISDNI-----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8INZ8-1", "uniprot_id": "Q8INZ8_DROME", "id": "Q8INZ8-1", "name": "Hydroxysteroid dehydrogenase-like protein 1", "aln": "---------------------MGLIYIVGSLSIAAFLYENLKSLFSIIKSVVEPFFRPNLPKTLAEKFGNWAVVTGATDGIGKEYARELARQGLNLVLVSRKEEKLIAVTNEIG-SQYNVKIKWIVADFAKGREVYAHIEKELNGIEVGILVNNVGT-IHDPESLDKVSEDMLWDLLTVNVGSVTMLTRKILPQMIS---------RRKGAIVNLGSSSELQPHPNLTAYAATKKFVTHFTKGLEYEVAEHNIHVQLVMPAFVATNMNSYSDKVRQGGLLFPNAYSYARSAVFTLG-------KTSETNGFWVHGLQYALMKLFP---MEIRTYFVYQLFKRMRIEAMEHRLKNQKLS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8BTX9-1", "uniprot_id": "HSDL1_MOUSE", "id": "Q8BTX9-1", "name": "Inactive hydroxysteroid dehydrogenase-like protein 1", "aln": "MAAVDSFYLLYREIARSCNCYMEALALVGAWYTARKSITVICDFYSLVRLHFIPRLGSR--PDLIKQYGRWAVISGATDGIGKAYAEELASHGLNVILISQEEEKLQAAAKHIA-DTYRVETLVLVADFSRGREIYAPIREALRDRDIGILVNDVGAFYPYPQYFSQVPEDTLWDIVNVNIAAASLMVHIVLPGMVE---------RKKGAIVTVSSGSCCKPTPQLAAFSASKAYLDHFSRALQYEYASKGIFVQSLIPFYVTSSGAAPASFLHRCPWLAPSPRVYAQHAVSTLG-------ISKRTTGYWSHSIQFLFAQYMP---EWLWVWGANLLNRSLRKEALSCQA------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4V8B7-1", "uniprot_id": "HSDL1_RAT", "id": "Q4V8B7-1", "name": "Inactive hydroxysteroid dehydrogenase-like protein 1", "aln": "MAAVDSFYLLYREIARSCSCYVEALALVGAWYTARKSIPVICDFYSLVRLHFIPRLGSR--PDLIKQYGRWAVISGATDGIGKAYAEELASHGLNIILISQEEEKLQAVAKHIA-DTYRVETLVLVADFSRGREIYAPIREALRDRDIGILVNDVGAFYPYPQYFSQVPEDTIWDIVNVNIAAASLMVHIVLPGMVE---------RKKGAIVTVSSGSCCKPTPQLAAFSASKAYLDHFSRALQYEYASKGIFVQSLIPFYVTSSVTAPGSFLRRCPWLAPSPRVYAQHAVSTLG-------ISKRTTGYWSHSIQFLFAQYMP---EWLWVWGANLLNRSLRKEALSSQA------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3SXM5-1", "uniprot_id": "HSDL1_HUMAN", "id": "Q3SXM5-1", "name": "Inactive hydroxysteroid dehydrogenase-like protein 1", "aln": "MAAVDSFYLLYREIARSCNCYMEALALVGAWYTARKSITVICDFYSLIRLHFIPRLGSR--ADLIKQYGRWAVVSGATDGIGKAYAEELASRGLNIILISRNEEKLQVVAKDIA-DTYKVETDIIVADFSSGREIYLPIREALKDKDVGILVNNVGVFYPYPQYFTQLSEDKLWDIINVNIAAASLMVHVVLPGMVE---------RKKGAIVTISSGSCCKPTPQLAAFSASKAYLDHFSRALQYEYASKGIFVQSLIPFYVATSMTAPSNFLHRCSWLVPSPKVYAHHAVSTLG-------ISKRTTGYWSHSIQFLFAQYMP---EWLWVWGANILNRSLRKEALSCTA------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A5WWC6-1", "uniprot_id": "HSDL1_DANRE", "id": "A5WWC6-1", "name": "Inactive hydroxysteroid dehydrogenase-like protein 1", "aln": "MAAVDSFQLLYREIARSCSGYVETLALVGACYMASKTVIFMRDCYSLIRLYFVPRLVRH--RDLSQQYGQWAIICGASEAIAKAYAEELARHGICVILISKDLSSVSDTARLIS-NNYGVEAICIEADFNQGPSACKPIKDAISSKDIGFLVNSFDGTLEISQNFLELSESVLWGTINRNIAATTLVTRLALPAMME---------KGRGAVVNISSGHCFHPIPRKAAFSASTAFLDNFSRSLHYEYGDQGVFVQSLLPFRVAS--QRPEGSAPPASWLVPSPQVYASHALSTLG-------ISHRTTGYWPHSMQLGLVKMMP---EWVWMLGSRVFTMAT---------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P38286-1", "uniprot_id": "MKAR_YEAST", "id": "P38286-1", "name": "Very-long-chain 3-oxoacyl-CoA reductase", "aln": "----MTFMQQLQEAGERFRCINGLLWVVFGLGVLKCTTLSLRFLALIFDLFLLPAVNFD---KYGAKTGKYCAITGASDGIGKEFARQMAKRGFNLVLISRTQSKLEALQKELEDQHHVVVKILAIDIAEDKESNYESIKELCAQLPITVLVNNVGQSHSIPVPFLETEEKELRNIITINNTATLLITQIIAPKIVETVKAENKKSGTRGLILTMGSFGGLIPTPLLATYSGSKSFLQGWSNSLAGELSKDAIDVELIISYLVTSSMSKIR----RSSLMIPNPQQFVKSTLRSVGRRCGSQERYATMTPYWAHAVYQFVITETFGVYSKIVNSINYSFHKSIRIRALKKAARQVKKE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .* : :. . : * :. : **::.*.* :*.::* :.: ::*::: ..: . : * . *.. : .***... . : : :. . : * :. : : : :* ::.:.* * * : ::.:. : : .* * : *: : . *.: : *.. :. :: : : * : . : : ", "identical_positions": 25, "similar_positions": 85, "identity": "6.98%" }, { "cls_id": "homologset.agr.RGD:1308434", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "G3V8G2-1", "uniprot_id": "G3V8G2_RAT", "id": "G3V8G2-1", "name": "26S proteasome non-ATPase regulatory subunit 5", "aln": "MAAQAVSLLREVARLEAPLEELRALQSVVQAVPLHELREQAAELRLRPLFSLLNQNN---------REQTALCVSILERLLQAVEPIHLARNLRLDLQRGLTHPDDSVKTLTLSQIGRIVEDSEAVTEVLSNAELLRQVVCCIGGENLSVAKAAIKSLSRISLTQAGLEALFESNLLDDLKNVMKTNDVVRYRVYELIIDISSVSSESLNYCTTSGLVTQLLRELTGEDVLVRATCIEMVTSLAYTHHGRQYLAQEGVIDQISNIIVGADSDPFSGFYLPGFVKFFGNLAVMDSPQQICERYPVFLEKVFAMADSQDPTMIGVAVDTVGILGSSVEGKQVLQKTGT-RFERLLTRIGYQAKNASTELKIRCLDAVSSLLYLSPEQQTDDFLGMTESWFSSVSR-DSLELFRGISNQPFPELHCAALKVFTAIANQPWAQKLMFNSPGFVEFVMDRSVEHDKTSKDAKYELVKALANSKTVAEIFGNSNYLRLRTYLSEGPYYVKPVATTAVEGAD--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BJY1-1", "uniprot_id": "PSMD5_MOUSE", "id": "Q8BJY1-1", "name": "26S proteasome non-ATPase regulatory subunit 5", "aln": "MAAQAVSLLREVARLEAPLEELRALQSVVQAVPLHELREQAAELRLRPLFSLLNQNN---------REQTALCVSILERLLQAVEPIHLARNLRLDLQRGLTHPDDSVKTLTLSQIGRIVENSEAVTEILNNAELLKQIVYCIGGENLSVAKAAIKSLSRISLTQAGLEALFESNLLDDLKNVMKTNDVVRYRVYELIIDISSVSSESLNYCTTSGLVTQLLKELTGEDVLVRATCIEMVTSLAYTHHGRQYLAQEGVIDQISNIIVGADSDPFSGFYLPGFVKFFGNLAVMDSPQQICERYPVFLEKVFEMADSQDPTMIGVAVDTVGILGSSVEGKQVLQKTGT-RFERVLMRVGYQAKNASTELKIRCLDAVSSLLYLSPEQQTDDFLGMTESWFSSMSR-DSLELFRGISNQPFPELHCAALKVFTAIADQPWAQRLMFNSPGFVEFVMDRSVEHDKASKDAKYELVKALANSKTVAEIFGNSNYLRLRAYLSEGPYYVKPVATTAVEGAD--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16401-1", "uniprot_id": "PSMD5_HUMAN", "id": "Q16401-1", "name": "26S proteasome non-ATPase regulatory subunit 5", "aln": "MAAQALALLREVARLEAPLEELRALHSVLQAVPLNELRQQAAELRLGPLFSLLNENH---------REKTTLCVSILERLLQAMEPVHVARNLRVDLQRGLIHPDDSVKILTLSQIGRIVENSDAVTEILNNAELLKQIVYCIGGENLSVAKAAIKSLSRISLTQAGLEALFESNLLDDLKSVMKTNDIVRYRVYELIIEISSVSPESLNYCTTSGLVTQLLRELTGEDVLVRATCIEMVTSLAYTHHGRQYLAQEGVIDQISNIIVGADSDPFSSFYLPGFVKFFGNLAVMDSPQQICERYPIFVEKVFEMIESQDPTMIGVAVDTVGILGSNVEGKQVLQKTGT-RFERLLMRIGHQSKNAPVELKIRCLDAISSLLYLPPEQQTDDLLRMTESWFSSLSR-DPLELFRGISSQPFPELHCAALKVFTAIANQPWAQKLMFNSPGFVEYVVDRSVEHDKASKDAKYELVKALANSKTIAEIFGNPNYLRLRTYLSEGPYYVKPVSTTAVEGAE--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VYG1-1", "uniprot_id": "PSMD5_DROME", "id": "Q9VYG1-1", "name": "26S proteasome non-ATPase regulatory subunit 5", "aln": "MEMEDNWWVTKLKALESKPQRLDALTAMNSAIAKEAALPRQIIERLLTTDQLYDCANPAADSHVPKDQAVDVTLELLCHCLDQLAMDTADEQLSSLLRRGLTHSNPALRAQVLASLFKKLLRQLTVGQVLT---LPNNELIFLILDELKQPDTQSTSLAINILSIVLPQRISNADVQAKLVQLLKQNEIVRCRAYELAVVLAKKSATLLS--DVTFILDAALSELDNDDVLLQASVMELLVPLAEQNHGLSYMERRRVLDIISYRVQRVEEHPLDALLVPSIMKFFGKISVY-QPLKIIGGYPHMLACLFMQLQSEDESILPTAMDTLANLATTPQGKILLNMHFSGAMEKSFKKYGSHTKKLSAHIKKRLLNSLD-VIYDFKTPPATEIINIGKNWYECFAGGAHANIIMDLINTPFPDLQMAALSFLKTICKYNWGIVALKNTGGAVEFLLSRQKDLHRDIKYMKWQIMEILS----ASAEFSPTETIRFTAYVNEGPYHVQADLDVATEPQGNA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : : :: **: :.* ** :: .*:. . : ** . .* : : : . : :.:* : *: : .:* *:*** *.: ::: .*:.: : : . :* ::*. * .: : : ::*. ..: .**: *: . : : :::: .* .::* *::** *.*** : ::. *. *. .: :: * ** .:***::*: :*::..** :** .*: :. *:* ** : .:..*:..: :*.::****:::* .* :* ** :: :* :*:* ::: .*:**:. *.:. :** :*: : :*: : : * ::*: ...:* * *:::. ::* : ::: : :.*:...: ::: .: . ***:*: ***..:.:*.. *. : *: * **:::.*. : .: * *::::: *: : *. .: :*: :*:.****:*:. .*.* ", "identical_positions": 110, "similar_positions": 211, "identity": "21.28%" }, { "cls_id": "homologset.agr.RGD:1308435", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A1L1V4-1", "uniprot_id": "LOL2B_DANRE", "id": "A1L1V4-1", "name": "Lysyl oxidase homolog 2B", "aln": "-----MLALWSISFVLLCSWRLSYAQYEHLGFAIAYQEPEQDL---YTPPELPADTPRIQLRLAGEKRKHNEGRVEVFYEGEWGTVCDDDFTIHAAQVICRELGYFEAISWSPSSKYGKGEGRIWFDNVHCKGKEKSLAQCESNGIGVSDCKHSEDVGVVCSDKRIPGFKFVNTLTNNINSLNIQVEDVRIRPILASYRKRIPVTEGYVEVKDGGKWKQICDDEWTQMNSRVICGMFGFPGQKRYNTRVYKMFARRRKPSYWDYTINCTGKEAHLSSCTLG--HTLS---NSTCEEGTPVVVSCIPGRAFAPTPMTGYKKAFRQEQPLVRLRGGAVVGEGRVEVLKNGEWGTICDDNWNLLAATVVCRELGFGSAKEALSGGQLGQGMGPVHMNEVQCSGFEKSVTECSFNMEKDSEGCSHEEDAGVKCNVPAMGFQQRLRLSGGRNPFEGRVEVLVERNGSLVWGTVCGEGWTTMEAMVVCRQLGLGFASNAFQETWYWPGAVNADAVVMSGVRCAGTEMSLSHCLHHG--EYLSCPKGGGRFAAGVSCSETAPDLVLNPQVVEQTTYLEDRPMFMLQCAYEENCLASTSSATPANS------PRRLLRFSSQIHNNGQSDFRPKISRENWVWHDCHRHYHSMEVFTHYDLLSTNGTKVAEGHKASFCLEDSECDEGIEKRYECANFGEQGITVGCWDTYRHDIDCQWVDITDVKPGDYIFQIVINPNYEVAESDYTNNIVKCRCRYDGHRIWMYNCHIGGSFSAETEDTFP---GLINNQVTHR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1QQC3-1", "uniprot_id": "LOL2A_DANRE", "id": "F1QQC3-1", "name": "Lysyl oxidase homolog 2A", "aln": "------MAVSSA----LCIFSL-------LVLAQAQSELQQ---------------PKIELRLAGDKRKHYEGRLEVFYNNEWGTVCDDDFSIEAAHVACRQLGFLGAVAWSPSAKFGQGEGRIWLDNVHCTGRENSLAACPSNGFGVSDCRHSEDVGVICNQKRIPGHRFINIMNNNVETLEERVEEIRIRPISS-HLKRIPITEGYVEVKERGKWRQICDEEWTPLNSRVACGMYGFPGEKNYNNKVYRSLSMRKKKNYWGFSVNCTGNEAHVSSCRLG--KALEPKRNGTCGRGLPVVVSCVPGRAFAPSSSIGFRKAYRPEQPLVRLRGGANVGEGRVEVLKNGVWGTVCDDNWNLKAATVVCRELGFGSAKEALTGAKLGQGMGPVHMNEVECSGFEKSLTDCYFNN--DALGCSHEEDAAVRCNVPAMGFQKRIRLSGGRNPFEGRVEVLAEKNGSLVWGTVCSENWGIIEAMVVCRQLGLGFASHAFQETWYWAGDANADNVVMSGVRCSGTEMSLPQCLHHG--KHINCPKGGGRFAAGVSCSDTAPDLVLNAQLVEQTTYLEDRPMYALQCALEENCLSSTARKNDHSS------YRRLLRFSSQIHNVGQSDFRPKLGYHAWTWHECHRHYHSMEVFTHYDLLSLNGTKVAEGHKASFCLEDTHCDEGISKRYHCANFGEQGITVGCWDTYRHDIDCQWIDVTDVKPGDYIFQVVINPNYDVAESDYTNNVMKCKCRYDGYRIWTYSCHIGGSRSSD-MDEYS---GMSNQLNHLR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B5DF27-1", "uniprot_id": "LOXL2_RAT", "id": "B5DF27-1", "name": "Lysyl oxidase homolog 2", "aln": "MEIPFGSCLYSCLALLVLLPSLSLAQYESWPYQLQYPEYFQQPPPEHHQHQVPSDVVKIQVRLAGQKRKHNEGRVEVYYEGQWGTVCDDDFSIHAAHVVCREVGYVEAKSWTASSSYGPGEGPIWLDNIYCTGKESTLAACSSNGWGVTDCKHPEDVGVVCSEKRIPGFKFDNSLINQIESLNIQVEDIRIRPILSAFRHRKPVTEGYVEVKEGKAWKQICDKHWTAKNSHVVCGMFGFPAEKTYNPKAYKTFASRRKLRYWKFSMNCTGTEAHISSCKLGPPMFRDPVKNATCENGQPAVVSCVPSQIFSPDGPSRFRKAYKPEQPLVRLRGGAQVGEGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGFGTAKEAVTGSRLGQGIGPIHLNEVQCTGTEKSIIDCKLNT--ESQGCNHEEDAGVRCNIPIMGFQKKVRLNGGRNPYEGRVEVLTERNGSLVWGNVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGNIFANKVIMSGVKCSGTELSLAHCRHD---EEVVCPEGGVQYGAGVACSETAPDLVLNAEIVQQTAYLEDRPMALLQCAMEENCLSASAVHTDPTRG-----HRRLLRFSSQIHNNGQSDFRPKNGRHAWIWHDCHRHYHSMEVFTYYDLLSLNGTKVAEGHKASFCLEDTECEGDIQKSYECANFGEQGITMGCWDMYRHDIDCQWIDITDVPPGDYLFQVVINPNYEVPESDFSNNIMKCRSRYDGYRIWMYNCHVGGAFSEETEQKFEHFSGLLNNQLSVQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P58022-1", "uniprot_id": "LOXL2_MOUSE", "id": "P58022-1", "name": "Lysyl oxidase homolog 2", "aln": "MELHFGSCLSGCLALLVLLPSLSLAQYEGWPYQLQYPEYFQQPAPEHHQRQVPSDVVKIQVRLAGQKRKHNEGRVEVYYEGQWGTVCDDDFSIHAAHVVCRQVGYVEAKSWAASSSYGPGEGPIWLDNIYCTGKESTLASCSSNGWGVTDCKHTEDVGVVCSEKRIPGFKFDNSLINQIESLNIQVEDIRIRPILSAFRHRKPVTEGYVEVKEGKAWKQICNKHWTAKNSHVVCGMFGFPAEKTYNPKAYKTFASRRKLRYWKFSMNCTGTEAHISSCKLGPSVTRDPVKNATCENGQPAVVSCVPSQIFSPDGPSRFRKAYKPEQPLVRLRGGAQVGEGRVEVLKNGEWGTICDDKWDLVSASVVCRELGFGTAKEAITGSRLGQGIGPIHLNEVQCTGTEKSIIDCKFNT--ESQGCNHEEDAGVRCNIPIMGFQKKVRLNGGRNPYEGRVEVLTERNGSLVWGTVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGNIFANNVVMSGVKCSGTELSLAHCRHD---EEVACPEGGVRFGAGVACSETAPDLVLNAEIVQQTAYLEDRPMSLLQCAMEENCLSASAVHTDPTRG-----HRRLLRFSSQIHNNGQSDFRPKNGRHAWIWHDCHRHYHSMEVFTYYDLLSLNGTKVAEGHKASFCLEDTECEGDIQKSYECANFGEQGITMGCWDMYRHDIDCQWIDITDVPPGDYLFQVVINPNYEVPESDFSNNIMKCRSRYDGYRIWMYNCHVGGAFSEETEQKFEHFSGLLNNQLSVQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y4K0-1", "uniprot_id": "LOXL2_HUMAN", "id": "Q9Y4K0-1", "name": "Lysyl oxidase homolog 2", "aln": "MERPLCSHLCSCLAMLALLSPLSLAQYDSWP---HYPEYFQQPAPEYHQPQAPANVAKIQLRLAGQKRKHSEGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSLINQIENLNIQVEDIRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGFPGERTYNTKVYKMFASRRKQRYWPFSMDCTGTEAHISSCKLGPQVSLDPMKNVTCENGLPAVVSCVPGQVFSPDGPSRFRKAYKPEQPLVRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNA--ESQGCNHEEDAGVRCNTPAMGLQKKLRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNKVVMSGVKCSGTELSLAHCRHDG--EDVACPQGGVQYGAGVACSETAPDLVLNAEMVQQTTYLEDRPMFMLQCAMEENCLSASAAQTDPTTG-----YRRLLRFSSQIHNNGQSDFRPKNGRHAWIWHDCHRHYHSMEVFTHYDLLNLNGTKVAEGHKASFCLEDTECEGDIQKNYECANFGDQGITMGCWDMYRHDIDCQWVDITDVPPGDYLFQVVINPNFEVAESDYSNNIMKCRSRYDGHRIWMYNCHIGGSFSEETEKKFEHFSGLLNNQLSPQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W2C9-1", "uniprot_id": "Q9W2C9_DROME", "id": "Q9W2C9-1", "name": "", "aln": "MCAIEDRKVLKMGLTLVCLTLLAIHMADAVVQHRSLEDARQERQRLVHRYTKVLNKEEGAIRLVGGD-NEYEGNIEVLHNGKWGAVCDDEWDSTEADIVCRQLGFPGMRRYTRSGFFGPARRRFWMDNLFCEGHEQELVDCHFEGWGENDCEPGEAAGVVCYPP-------ENALIP-MATPIIRDEDLPKYPIHS-------------------------------------------------------------------------------------------------------------------------------RSRLYVRLRGGRSRIEGRVEVS------------------------------------------------------------------------------------------------LDGGR------------------WGSVCADGWSLLEANVVCRQLGLGYASEAFQTDFFGG--FNVSRPVLSGSECYGNETELADCLHHDASQGIISCHGNRQHVAAVICDYIAPDLVVDYLEIEQTAHLEDRPMLLMQCAMEENCVANEAYQIQRDDPHWRYRSRRLLKFTAAAINAGNADFRPFKEKSQWEWHMCHMHFHSMEVFATFDIFNLRGIKVAQGHKASFCLEDSNCLPGVAKKYNCANYGDQGISINCSDVYLYNLDCQWVDVTDLIPGTYVLKIAINPEFKVAEMNYDNNAAICDLIYTANFARVQNCQLGRP-----------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : * . :**.* . :. **.:** ::.:**:****:: *.: **::*: :: *. :* .. :*:**:.* *.* *. * :* * .**. * .**:* * : : . : *:: .* : .: ****** ****** *.*** ** **.:.* :** *********:**.*** :: . ::** .* *.* .*..* *. : : . .*. :. *.* *. *****:: ::**::****** :*** ****:: : ****:*:: * *::**** * ** ** *:******: :*::. .* ***:**********:.* .: * *.***:*:***::.* * * :::****:*:**: ** *::::.***::.*.* :: ** * * . .*::* . ", "identical_positions": 181, "similar_positions": 131, "identity": "23.03%" }, { "cls_id": "homologset.agr.RGD:1308437", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "B2RZ66-1", "uniprot_id": "B2RZ66_RAT", "id": "B2RZ66-1", "name": "Signal recognition particle 19 kDa protein", "aln": "---------------------------------------------------------------MACAAAR----SP----------------ADQDRFICIYPAYLNNKKTIAEGRRIPINKAVENPTATEIQDVCSAVGLNAFLEKNKMYSREWNR-----------------DVQYRGRVRVQLKQE--------DGSLCLVQFPSRKSVMLYVAEMIPKLKTRTQKSGGADPS-------LQQ----------GEGSKKGKGKKKK----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P09132-1", "uniprot_id": "SRP19_HUMAN", "id": "P09132-1", "name": "Signal recognition particle 19 kDa protein", "aln": "---------------------------------------------------------------MACAAAR----SP----------------ADQDRFICIYPAYLNNKKTIAEGRRIPISKAVENPTATEIQDVCSAVGLNVFLEKNKMYSREWNR-----------------DVQYRGRVRVQLKQE--------DGSLCLVQFPSRKSVMLYAAEMIPKLKTRTQKTGGADQS-------LQQ----------GEGSKKGKGKKKK----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9D7A6-1", "uniprot_id": "SRP19_MOUSE", "id": "Q9D7A6-1", "name": "Signal recognition particle 19 kDa protein", "aln": "---------------------------------------------------------------MACSAAR----PP----------------ADQDRFIFIYPAYLNNKKTIAEGRRIPISKAVENPTATEIQDVCSAVGLNAFLEKNKMYSREWNR-----------------DVQFRGRVRVQLKQE--------DGSLCLVQFPSRKSVMLYVAEMIPKLKTRTQKSGGADPI-------LQQ----------GEGSKKGKGKKKK----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49963-1", "uniprot_id": "SRP19_DROME", "id": "P49963-1", "name": "Signal recognition particle 19 kDa protein", "aln": "---------------------------------------------------------------MATAVPMKKNWSPSM------------KHNDMERWICIYPAYINRKKTRQEGRRLPKENCVDNPSYIEIRDVLSVSNLQFLME-NKKYCRENSS-----------------EMEFRGRVRVQLRNV--------DGTLYNNDFPTRESIMLHIASKIPQLKTRQNKSGDSYHQ-------QSQPQSNASGSGGGGGGKKGKGKRR-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P29478-1", "uniprot_id": "SEC65_YEAST", "id": "P29478-1", "name": "Signal recognition particle subunit SEC65", "aln": "MPRLEEIDDFNDIDDLDMELAELDPSLRTPIAPKITPKVVRSQDQENPAFLPGTNNNSNSNNNSSNEKEQLSFINPKTGKVERSEAISKKDLEEVKRFQVLYPCYFDINRSHKEGRRVPKELAVENPLAKTMADAVRELGILCIFEGEKCHPQDFGNPGRIRVLFKENGQLIGAATKFKGGKRQLMKAVGEYMKRHPTTIESLREIPYGPDFDNIEFKKIPRVKGFKMNEIVPLHSPFLMGHPMTKSVYETPKITAAEKSFKPPKNKYKVVRR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : .*: :**.*:: ::: ****:* . .*:** : *. .: ::* :* : :: . :::* * :: ::* .. . **::* : . : . . * :: ", "identical_positions": 23, "similar_positions": 45, "identity": "8.42%" }, { "cls_id": "homologset.agr.RGD:1308438", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P56399-1", "uniprot_id": "UBP5_MOUSE", "id": "P56399-1", "name": "Ubiquitin carboxyl-terminal hydrolase 5", "aln": "MAELSEEALLSVLPTIRVPKAGDRVHKDECAFSFDTPESE---------GGLYICMNTFLGFGKQYVERHFNKTGQRVYLHLRRTRRP-KEEDTSAGTGD---PPRKKPTRLAIGVEGGFDLTEDKFEFDEDVKIVILPDYLEIARDGLGGLPD-IVRDRVTSAVEALLSADSASRKQE----VQAWDGEVRQVSKHAFNLKQLDNPARIPPCGWKCSKCDMRENLWLNLTDGSILCGRRYFDGSGGNNHAVEHYRETG-YPLAVKLGTITPDG-ADVYSYDEDDMVLDPS---LAEHLSHFGIDMLKMQKTDKTMTELEIDMNQRIGEWELIQESGVPLKPLFGPG--YTGIRNLGNSCYLNSVVQVLFS--IPDFQRKYVDK-LEKIFQNAPTDPTQDFSTQVAKLGHGLLSGEYSKPALESGDG-EQVPEQKEVQDGIAPRMFKALIGKGHPEFSTNRQQDAQEFFLHLINMVERNCRSSE-----NPNEVFRFLVEEKIKCLATEKVKYTQRVDYIMQLPVPMDAALNKEELLEYEEKKRQAEEEKVPLP--ELVRAQVPFSSCLEAYGAPEQVDDFWSTALQAKSVAVKTTRFASFPDYLVIQIKKFTFGLDWVPKKLDVSIEMP------EELDISQLRGTG-LQPGEEELPDIAPP-LVTPD-EPKGSLGFYGNEDEDSFCSPHFSSPTSPMLDESVIIQLVEMGFPMDACRKAVYYTGNSGAEAAMNWVMSHMDDPDFANPLILPGSS-GPGSTSAAADPPPEDCVTTIVSMGFSRDQALKALRATNNSLERAVDWIFSHIDDLDAEAAMDISEG-RSAAES-ISESVPVGPKVRDGPGKYQLFAFISHMGTSTMCGHYVCHIKK----EGRWVIYNDQKVCASE--KPPKDLGYIYFYQRVVS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZVQ0-1", "uniprot_id": "D3ZVQ0_RAT", "id": "D3ZVQ0-1", "name": "Ubiquitin carboxyl-terminal hydrolase", "aln": "MAELSEEALLSVLPTIRVPKAGDRVHKDECAFSFDTPESE---------GGLYICMNTFLGFGKQYVERHFNKTGQRVYLHLRRTRRP-KEEDSSAGTGD---PPRKKPTRLAIGVEGGFDLTEDKFEYDEDVKIVILPDYLEIARDGLGGLPD-IVRDRVTSAVEALLSADSASRKQE----VQAWDGEVRQVSKHAFNLKQLDNPARIPPCGWRCSKCDMRENLWLNLTDGSILCGRRYFDGSGGNNHAVEHYRETG-YPLAVKLGTITPDG-ADVYSYDEDDMVLDPS---LAEHLSHFGIDMLKMQKTDKTMTELEIDMNQRIGEWELIQESGVPLKPLFGPG--YTGIRNLGNSCYLNSVVQVLFS--IPDFQRKYVDK-LEKIFQNAPTDPTQDFSTQVAKLGHGLLSGEYSKPALESGDG-EQVPEQKEVQDGIAPRMFKALIGKGHPEFSTNRQQDAQEFFLHLINMVERNCRSSE-----NPNEVFRFLVEEKIKCLATEKVKYTQRVDYIMQLPVPMDAALNKEELLEYEEKKRQAEEEKVALP--ELVRAQVPFSSCLEAYGAPEQVDDFWSTALQAKSVAVKTTRFASFPDYLVIQIKKFTFGLDWVPKKLDVSIEMP------EELDISQLRGTG-LQPGEEELPDIAPP-LVTPD-EPKGSLGFYGNEDEDSFCSPHFSSPTSPMLDESVVIQLVEMGFPMDACRKAVYYTGNSGAEAAMNWVMSHMDDPDFANPLILPGSS-GPGSTSAAADPPPEDCVATIVSMGFSRDQALKALRATNNSLERAVDWIFSHIDDLDAEAAMDISEG-RSAADS-ISESVPVGPKVRDGPGKYQLFAFISHMGTSTMCGHYVCHIKK----EGRWVIYNDQKVCASE--KPPKDLGYIYFYQRVVS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P45974-1", "uniprot_id": "UBP5_HUMAN", "id": "P45974-1", "name": "Ubiquitin carboxyl-terminal hydrolase 5", "aln": "MAELSEEALLSVLPTIRVPKAGDRVHKDECAFSFDTPESE---------GGLYICMNTFLGFGKQYVERHFNKTGQRVYLHLRRTRRP-KEEDPATGTGD---PPRKKPTRLAIGVEGGFDLSEEKFELDEDVKIVILPDYLEIARDGLGGLPD-IVRDRVTSAVEALLSADSASRKQE----VQAWDGEVRQVSKHAFSLKQLDNPARIPPCGWKCSKCDMRENLWLNLTDGSILCGRRYFDGSGGNNHAVEHYRETG-YPLAVKLGTITPDG-ADVYSYDEDDMVLDPS---LAEHLSHFGIDMLKMQKTDKTMTELEIDMNQRIGEWELIQESGVPLKPLFGPG--YTGIRNLGNSCYLNSVVQVLFS--IPDFQRKYVDK-LEKIFQNAPTDPTQDFSTQVAKLGHGLLSGEYSKPVPESGDG-ERVPEQKEVQDGIAPRMFKALIGKGHPEFSTNRQQDAQEFFLHLINMVERNCRSSE-----NPNEVFRFLVEEKIKCLATEKVKYTQRVDYIMQLPVPMDAALNKEELLEYEEKKRQAEEEKMALP--ELVRAQVPFSSCLEAYGAPEQVDDFWSTALQAKSVAVKTTRFASFPDYLVIQIKKFTFGLDWVPKKLDVSIEMP------EELDISQLRGTG-LQPGEEELPDIAPP-LVTPD-EPKGSLGFYGNEDEDSFCSPHFSSPTSPMLDESVIIQLVEMGFPMDACRKAVYYTGNSGAEAAMNWVMSHMDDPDFANPLILPGSS-GPGSTSAAADPPPEDCVTTIVSMGFSRDQALKALRATNNSLERAVDWIFSHIDDLDAEAAMDISEG-RSAADS-ISESVPVGPKVRDGPGKYQLFAFISHMGTSTMCGHYVCHIKK----EGRWVIYNDQKVCASE--KPPKDLGYIYFYQRVAS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1MT86-1", "uniprot_id": "Q1MT86_DANRE", "id": "Q1MT86-1", "name": "Ubiquitin carboxyl-terminal hydrolase", "aln": "MTEVS-EILMSVLSAIRVPRPGDRVHKDECAFSFSSPESE---------GGLYVCMNSFLGFGSKYVDRHHAKTGQRAYLHITRTRKTQKEDDPNSGSGD---PPKKKPTRLAIGIEGGFDVEQE--QYEEEVKVVLFPDRQEVTLDDLSSMPD-VVRERVSLSVAELQAADSVSHTLQ----VQQWDGEVRQESKHAAELKQLDNGLKIPPSGWKCEVCELQENLWMNLTDGKVLCGRRYFDGSGGNNHALLYYQQTG-YPLAVKLGTITPDG-ADVYSYDEDDMVLDSK---LPEHLSHFGIDMMTMEKTERTMTELEIAVNQRVGEWEVIQESGTTLRPLWGPG--LTGMKNLGNSCYLNSVMQVLFT--IPDFQTKYVSN-IDKIFDEAPSDPTQDFKTQVAKLGYGLLSGEYSKPAPDPADEPNTSAEPRGDQVGIAPRMFKALVGRGHPEFSTNRQQDAQEFLLHFINMVERNCRSGM-----NPSEAFRFLVEEKIVCQQSQKAKYTQRVDYIVQLPVPMDQATNMDELQEAERRREEAESSGAPPP--VAPRAQIPFAACLAALSEPETLTDFWSSAVQAKTTATKTTRFASFPDHLVIQIKKFTFGLDWVPKKLDVSIDVP------ETLDLNALRAMG-QQPGEELLPEVAPPPLMTPDVEVKGILGSHGNEEDDSLYSPLLS----PVLDDSTVSQLCEMGFPLEACRKAVYYTGNTGIDAAMNWVMGHMDDPDFAAPLVLPGSSSAPGTTPTES--LPEEHLATIVSMGFSRDQATRALRATNNVLERAVDWIFSHLDDLES---MDVSEGGRSEGGSEASREPPPGPRVRDGTGKYELFAFISHMGSSTMCGHYVCHIKK----DQQWVIFNDQKVCASE--KPPKDLGYLYFYRRVVE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VZU7-1", "uniprot_id": "Q9VZU7_DROME", "id": "Q9VZU7-1", "name": "Ubiquitin carboxyl-terminal hydrolase", "aln": "MEELR-KHLSKVNVPCASGAGSPPIYKDECVYSYDNPETP---------TGLYVCLHSFLGFGEAYVREYADKTGNRVFLHIQRVKTIKEGADMEAECAESEAGPERKITRLAIGVEGGYNESDMAKKYEIKDTYSIVVAP---HLDKKLPYPDPELPMRVTQSVEAILAADSAIAKLEKATLMGTWDGEVRQASKYADNLQQLDNGKRIPPSGWQCEKCDLTNNLWLNLTDGSIMCGRKFFDGSGGNDHAVEHYRVTG-FPLAVKLGTITADGKSDVFSYPEDEMVLDPH---LERHLSHFGINMAAMKKSEKSMVELELDINQRIGEWTALTESESELQPVAGPG--YTGMRNLGNSCYINSVMQVLFV--IPDFQQRFVGTGAERYFKEFPSDPANDFNIQMAKLGTGLQSGKYSSIAENTLDT--------DHSTGISPAMFKNIVGKNHPDFSTKQQQDANDFYLHLLTLLDRNSRNQT-----NPADALKFLLEDRVECLASHKVKYNTREEYSFRLPVPLDKATNLDEVREFQERKKAARETGQRLPDRDIVRHKVPLQACLERFFGPELIEQFYSTAIGSKTNARKITRLATMPDCLMIHVGKFTLGDDWVPKKLDVSVDMP------DELDLSNWRSAGGLQPGEEALPEPATE-------EVKFAF------------------------DEAVMSELLTMGFPPEACKRACYHTKNSGLEAASNWLMEHIADEDISEPFVVPNNS--IGDCAANQFVANPESLAMLMSMGFDERQAVAALKATDGNVERATDWIFSHADSIGVEDAAPAANS-SAAAAS----STPNKTNYRDGRGKYRLVAFISHMGTSAQVGHYVCHIRK----KGEWVIFNDSKVAKSQ--NPPKDLGYLYLYMREQ-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38237-1", "uniprot_id": "UBP14_YEAST", "id": "P38237-1", "name": "Ubiquitin carboxyl-terminal hydrolase 14", "aln": "---MAEAVLENVNVPAVVS-------KDECIYCFESPYNEPLALNASPKHSLNICLNCFQATCNRHVPLHIRVTEYACDTIHSNYLTIAKVEKPKQENVE----ENNNNKKIKLQVIETSEDDTHNTIWSLQR-----FNGENVPRTVLSKSTDSDISSTALEKIEKILKAKSQDFEDK----KNSWVLEISTCPHTEN--FQIPSKPENTVNLNQCSSCDLTQNLWLCLHCGNIGCGREQIG-IDGHSHALDHYRSNNNHPLAIKLGSLSSST-YDLYCYACDDETRFPDNVNLGSALQIYGINIQEKIADEKTLVQLQVEQNE-NWQFRMVDSSGKEFEKLSASKNYGCGLINLGNSCYLNSVIQSLVNGGVPNWSLDFLGS----KFPLDVVYPDNNLKCQWIKLLNAMKCEPELYPN------------------GIKPTTFKKCIGQNHQEFSSNRQQDAMEFLTFLLDLLDKKFFSSSSSGIPNPNDLVRFMMEDRLQCNICGKVKYSYEPTEAIQIPLEEN-----DEPQDMLERIKAYFEG---------------------------QTIEFKCANCKEKVTANKKPGFKSLPQTLILNPIRIRL-QNWIPVKTSNELSLPGLIDRDDMLDVSSYLSQGFDPQTENLLPDEDENRSSFTP-------------------------------NQCSISQLIEMGFTQNASVRALFNTGNQDAESAMNWLFQHMDDPDLNDPFVPPPNV-----PKKDKREVDEVSLTSMLSMGLNPNLCRKALILNNGDVNRSVEWVFNNMDDDGTFPEPEVPNE----------EQQQKKDLGYSTAKPYALTAVICHKGNSVHSGHYVVFIRKLVADKWKWVLYNDEKLVAADSIEDMKKNGYIYFYTRC--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * .* . **** :.:..* . .* :*:: * . . :* : * . : . : ..: .:: : : : . . .* : . : : *.* : * *: .: *: . . . :*. *:: :***: * *.: ***. :. .*:.**: :*: .. .***:***:::.. *::.* *: . . * *. :**:: ::::.:*:: *: :: : .* :. : .. *: *******:***:* *. :*::. ::.. * * :::. * ** .: . ** * ** :*:.* :**:::**** :* .:: ::::: . ** : .:*::*::: * *.**. . .::*: : :* : .: . . :* .: * * * . : ::*: *::: :: : :*:* * . .:.:* : **:. . * *: **: ::. : :* ***. :*. :* : * * . ::* **:: *: * *: *:: * . :: ::***:. . ** .:. ::*:.:*:*.: *. .: . . * * *.*.* *.*. **** .*:* . .**::**.*: :: : *. **:*:* * ", "identical_positions": 156, "similar_positions": 246, "identity": "17.11%" }, { "cls_id": "homologset.agr.RGD:1308439", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "O08664-1", "uniprot_id": "BCL7C_MOUSE", "id": "O08664-1", "name": "B-cell CLL/lymphoma 7 protein family member C", "aln": "MAGRTVRAETRSRAKDDIKKVMATIEKVRRWEKRWVTVGDTSLRIFKWVPVVDPQEEERRRAGGGAERSRGRERRGRGTSPRGGGPLILLDLN-DENSNQSFHSEGSLQKGAEPSPGGTPQPSRPGSPTGPPEVITEDTQPPQLGQERDPGGTPAGGTDEPPKLTKEEPVPELLEAEAPEAYPVFEPVPSVPEAAQGDTEDSEGAPPLKRICPNAPDP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZUL4-1", "uniprot_id": "D3ZUL4_RAT", "id": "D3ZUL4-1", "name": "", "aln": "MAGRTVRAETRSRAKDDIKKVMATIEKVRRWEKRWVTVGDTSLRIFKWVPVVDPQEEERRRAGGGAERSRGRERRGRGTSPRGGGPLILLDLNADENSNQSFHSEGSLQKGTEPSPGGTPQPSRPGSPTGPPEVITEDTQPPQLGQERDPGGTPAGGTDEPPKLTKEEPVPELLEAEAPEAYPVFEPVPPVPEAAQGDTEDSEGAPPLKRICPNAPDP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8WUZ0-1", "uniprot_id": "BCL7C_HUMAN", "id": "Q8WUZ0-1", "name": "B-cell CLL/lymphoma 7 protein family member C", "aln": "MAGRTVRAETRSRAKDDIKKVMATIEKVRRWEKRWVTVGDTSLRIFKWVPVVDPQEEERRRAGGGAERSRGRERRGRGASPRGGGPLILLDLN-DENSNQSFHSEGSLQKGTEPSPGGTPQPSRPVSPAGPPEGVPEEAQPPRLGQERDPGGITAGSTDEPPMLTKEEPVPELLEAEAPEAYPVFEPVPPVPEAAQGDTEDSEGAPPLKRICPNAPDP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O76857-1", "uniprot_id": "O76857_DROME", "id": "O76857-1", "name": "", "aln": "-MSRSVRAETRSRAKDDIKRVMQAVDKVRHWEKKWVTISDTTMKIYKWVPIASASEKKAKLESSPGSAAVRRPPPGSGVTPVGGS-----------------------KSDKENSQKGTPTPP---QITPSYQGLTAEDSNTCFSVVSDSQGA--------------------------------DFVSSMPFSEDSNSQGSDG--PVKRLKTSD---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .*:**************:** :::***:***:***:.**:::*:****:....*:: : .. .. : * * *.:* **. :.. * * *** *. . : . : :. : . . :. *. * : *..:* : :.:::.*:* *:**: .. ", "identical_positions": 55, "similar_positions": 62, "identity": "25.23%" }, { "cls_id": "homologset.agr.RGD:1308441", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6G9D3-1", "uniprot_id": "A0A8I6G9D3_RAT", "id": "A0A8I6G9D3-1", "name": "", "aln": "MLMYRGTHLNRSNSNIHHHFFCIVMSFPLTVSPASPSHYCQTQGLKHSRADTVYWENPERTFDLVLKVKCHASENEDP------------VVLWKFPEDFGDQEVLQSVPRFCFPFDVERVSQNQVGQHFTFVLTDMESKQRFGFCRLTSGGRVCLCILSYLPWFEVYYKLLNTLADYLAKELEDDLNETLKSLYSHPVPKANTPVHLSV--------------------HSCFITPDITGLPTIPESRNLTEYFVAVDVNNMLRLYASMLHERRIIITSSKLSTLTACLHGSAALLYPMYWQHIYIPVLPPHLLDYCCAPMPYLIGIHSSLIERVKNKSLEDVVMLNVDTNTLESPFNDVNSLPSDVVSALKNKLKKQSTATGDGVARAFLRAQAALFGSYRDALRYKPGEPITFCEESFVKHRSSVMKQFLETAVNLQLFKQFIDGRLAKLNAGRGFSDIFEEEITSGGFCGGSPRSYQQWVYTVKKGGALFNTAVTKATP---AVRTAYKFAKSHARLGLKEVKSRLRHK------DNEEDYGTCSGLVQY---------------------TPVYTLHHERGETREKQKLSQAHLKRPHKSLDGTLYDDDDD---IERASKISSEDGEETSAYFYESDDS-VDAQVKAPYSGEMD----LLGEILDTLSTHSSDQGK------------------------------------------------LAPAKSLDFFRSMDDIDYKPTN--KSNAPSENNLTLLCA-SGDQGE--WNLGQDDSALHGKHLPPSPRKRVCSSG-------------LTDSLFILKEENTEKPFSADSVSVPTVVEKSASTSDSGFQPATPEASQTH-----KGKPEVKQTLSQA---SDDLLVPSPGNRQSTFVPWEKA------GKE--------------ETKPSKDVGLLQEV--VSLCHMSCDFQQGLNISEESKSENQT---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3U1T9-1", "uniprot_id": "DEN1B_MOUSE", "id": "Q3U1T9-1", "name": "DENN domain-containing protein 1B", "aln": "-------------------------------------------------MDRRTRENPERTFDLVLKVKCHASENEDP------------EVLWKFPEDFGDQEVLQSVPKFCFPFDVERVSQNQVGQHFTFVLTDMESKQRFGFCRLTSGGRICLCILSYLPWFEVYYKLLNTLADYLAKELEEDLNETLKSLYNHPVPKANTPVNLSV--------------------HSCFITPDITGLPTIPESRNLTEYFVAVDVNNMLRLYASMLHERRIIITSSKLSTLTACLHGSAALLYPMYWQHIYIPVLPPHLLDYCCAPMPYLIGIHSSLIERVKNKSLEDVVVLNVDTNTLESPFNDLSSLPSDVVSALKNKLKKQSTATGDGVARAFLRAQAALFGSYRDALRYKPGEPITFCEESFVKHRSSVMKQFLETAVNLQLFKQFIDGRLAKLNAGRGFSDIFEEEITSGGFCGGSPRSYQQWVYTVKKGGALFNTAVTKATP---AVRTAYKFAKSHARLGLKEVKSRLKHK------DNEEEYGTCSGLVQY---------------------TPVYTLHNEKGENREKHKLSQTHLKRPHKSLDGTLYDDDDDDDDIERASKISSEDGEETRAYFYESDDS-VEAQVKAPYSGEMD----LLGEILDTLSTHSSDQGK------------------------------------------------LAPAKSLDFFRSMDDIDYKPTN--KSNAPSENNLALLCA-SGDQGE--WNLGQDDSALHGRQLPPSPRKRVSSGG-------------LTESLFILKEESREKPLCADSVSGPTVVGKPAPTSGLRSQPAAPEASQTE-----RGRAEVKQTPGQAPLQSEDLSVPGPGSRQSTFVPWEKA------GKE--------------DTKPSKDVGLLQEV--VSLCHMSCDFQQDLNISEESRSGNQT---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6P3S1-1", "uniprot_id": "DEN1B_HUMAN", "id": "Q6P3S1-1", "name": "DENN domain-containing protein 1B", "aln": "-------------------------------------------------MDCRTKANPDRTFDLVLKVKCHASENEDP------------VVLWKFPEDFGDQEILQSVPKFCFPFDVERVSQNQVGQHFTFVLTDIESKQRFGFCRLTSGGTICLCILSYLPWFEVYYKLLNTLADYLAKELENDLNETLRSLYNHPVPKANTPVNLSVNQEIFIACEQVLKDQPALVPHSYFIAPDVTGLPTIPESRNLTEYFVAVDVNNMLQLYASMLHERRIVIISSKLSTLTACIHGSAALLYPMYWQHIYIPVLPPHLLDYCCAPMPYLIGIHSSLIERVKNKSLEDVVMLNVDTNTLESPFSDLNNLPSDVVSALKNKLKKQSTATGDGVARAFLRAQAALFGSYRDALRYKPGEPITFCEESFVKHRSSVMKQFLETAINLQLFKQFIDGRLAKLNAGRGFSDVFEEEITSGGFCGGNPRSYQQWVHTVKKGGALFNTAMTKATP---AVRTAYKFAKNHAKLGLKEVKSKLKHK------ENEEDYGTCSSSVQY---------------------TPVYKLHNEKGGNSEKRKLAQARLKRPLKSLDGALYDDEDDDD-IERASKLSSEDGEEASAYLYESDDS-VETRVKTPYSGEMD----LLGEILDTLSTHSSDQGK------------------------------------------------LAAAKSLDFFRSMDDIDYKPTN--KSNAPSENNLAFLCGGSGDQAE--WNLGQDDSALHGKHLPPSPRKRVSSSG-------------LTDSLFILKEENSNKHLGADNVSDP--------TSGLDFQLTSPEVSQTD-----KGKTEKRETLSQI---SDDLLIPGLGRHSSTFVPWEKE------GKE--------------AKETSEDIGLLHEV--VSLCHMTSDFQQSLNISDKNTNGNQT---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58IIA5-1", "uniprot_id": "A0AC58IIA5_DANRE", "id": "A0AC58IIA5-1", "name": "", "aln": "-------------------------------------------------MDSRINENPARTFDLALQVACPSSENEDP------------TVLWKFPQDFGDQEVLQTVPKFCFPFDVERVSPTQVGQNFTFVLTDIESKQRFGFCRLTSGCKLCICLLSYLPWFEIYYKLLNTLADYLSKHQEDDLNDMLETLHNHPVPKPNTPVNLSVSNHLHFANGQVVQHPGSRQLHSYFVAPDINGLPTIPESRNLTEYFVAVDVNNMLHLYASMLHERRIIITSSKLSTLTACVHGSTAMLYPMHWQHIFIPVLPPHLLDYCCAPMPYLVGVHLSLLERVKSRSLEDVVILNVDTNTLESPTDDLHNLPSDVVSSLKSKLKKQSTATGAGVARAFLHAQAALFGSYRDALRYKPGEPITFCEKSFVAHRSSAMRGFLEMAVNLQLFKQFIEGRLAKLNAGRGFTDVYEEEITEGGFCKSNSKSYQQWIHTKMR---------ERAKP---VVKN-FQMAKDHAKRKIRDMKDKITQK------DTEEEE---SPYCEG---------------------SPTSTKSLS---PRRLQRIAYQNLKSSPHTLYPDSYNNDDN------ASRISSEDSGEVPSYNEDSDESDLELRSEVSQSGQMN----LLEEILDSLSTSHIEQGR------------------------------------------------LSAAKSLDFFRSFEDLDYNPKKSFKSPLCSSPTATGCEVGNGEPAG--WKTGQDDSAVHGKHLPPSPRRQTSSCS-------------LPVHPPPPTEDIPMRNSLPETPTIQILFPDMEKATNSADGLLSPEKKHPA-----ARSLSRQKVLSRKTQRPHQEHKTASG-QLSVHVPWEREKQLLGTGIEG-------------DSSETQEKGLLEEI--ESMCRISMAFDSNQEFIQNNSSRDKS---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z7Q5-1", "uniprot_id": "A1Z7Q5_DROME", "id": "A1Z7Q5-1", "name": "UDENN domain-containing protein", "aln": "-------------------------------------------------MGSRIKNDVKKLFEFWCEVTPTPGLERGTSSRSGGPAVPAGVIVESFPEGFRDQEVLTGIPSFAFPCDTTSTS----VQTYSFVHTTGDSKWRFGFCRQDPRTNTAMVLITYLPWHDTFLKLLPVLAELRRTD-PNGFRTFLSEAYNQGIPDCGGSLKVYYSAG---------------QSHFTFERPLQFQLPSMPENHNLNLYYNFVEPKEMIAVFAAMLAERRIIFTSRHLDRLSSCIQAANAFLYPMVWQHIFIPVLPWEFKDYLGAPMPYLIGVPEPVLETVTSDELGEVVILNCDTKIFESPFDDVHNLPTEIVSQLKKHLNHTHDHIGDRISKIFLNALVQLIGGYRDAVEYHE-NSKTFNSQKFIESRPAHLRPFLAKMMDLQIFAQFIDDRLTMLNSGLGFSDEFELETVRYAEKKKRGRNYAIMKNLKDKTNPAVKSAVKSVKEGSRGMKTAYKGFKTKLRENGNQFGGTHFHFGLGSPNHSDRPDGTSGGYVRGGKAIGAAHHSAPSSPVTSKRLDGIASVTGSSGSGGSGAREPREFLRRGPVPLAMSSSSSHIQPNGHAYGASAGAHYGHHLAASPAVSSASSLCSSSEMNLSQELQNHPLFKTPAVDRSLKPNAEHRRGAAPPARPPPPQSTPASYYNHPYAAHPHVESKPPRHTSTPTRPRQPLPTADSSSFDSPPDVQSPPIPPRRQGSSNAIVAATAAAVSAEISKLERNCWKDEPGNDSVRSSNASSSSATSSSSGASFVTAASTFSHLNVSDPPIPTPRAKREQQQPLEDSMNDLISLDDSNNTSFDLEDFDPLNQNARPLPPLSTAFAKKCSTLPAGVNSSVVASSVSNPLYPYFAPKHMATVAAVTGRTPPMHPPPQIQRNTIAAKPDDDFELLRKYGLDQFTLNANGTEKSQQLTTGKGMNNWTTFD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : *:: :* .. :... :: .**:.* ***:* :* *.** *. .* * ::** * :** ****** . .: :::****.: : *** .**: .. :.:. * :.: :*. . .::: * * * **::**.:**. *: *: ::*: ::*:** ****:: * :*. *::*::.: *:**** ****:***** .: ** ******:*: .::* *.. .* :**:** **: :*** .*: .**:::** **.:*:: * ::: **.* . *:*.****:.*: :. ** .:.*: *.: :: ** ::**:* ***:.**: **:* **:* :* * . . :.* : .. ::. :: * : : .:. . : ..:. . . . . : . *: .* ... : .: .:. . . : *. * : : * ::: : :* . :: : : :.*:* ..:. * . .* . : .. *: .:.:::. : ..*. .* . :. . : : :. * .:. : . . . . ..* . * . .: **.: .: : :.. :: . : : ", "identical_positions": 157, "similar_positions": 247, "identity": "16.05%" }, { "cls_id": "homologset.agr.RGD:1308443", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZDQ2-1", "uniprot_id": "D3ZDQ2_RAT", "id": "D3ZDQ2-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------SLGQWPIFSSPPAATARGAAAGAGADGTLAPLLELQTEAARRWARRPPVTAYISACFPRR--------ERRRTGFSVKDILDLPDTNDEEGSVAEGPEEEN-----EGPEPAKRAGPLGQS---------------------------------------------------------------------ALDAVQSLPLKSP------FYDSSDNPYTRWLASTEG-------------------------------------LQYS----------LHGLAASAPPQDSSSKSPE-----------------------------------------------------PSADESPDNDKETQ----------------------------------------GGGGDAG-------KKRKRRVLFSKAQTYELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQNHRYKMKRARAEKGMEVTP---------------LPSPRRVAVPVLVRDGKPCH-----------ALKAQDLAAATFQAGIPFSAYS-AQSLQHMQYNAQ----YSSASTPQYPTAHPLVQAQQWTW--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P42586-1", "uniprot_id": "NKX22_MOUSE", "id": "P42586-1", "name": "Homeobox protein Nkx-2.2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSLTN-------------TKTGFSVKDILDLPDTNDEDGSVAEGPEEES-----EGPEPAKRAGPLGQG---------------------------------------------------------------------ALDAVQSLPLKSP------FYDSSDNPYTRWLASTEG-------------------------------------LQYS----------LHGLAASAPPQDSSSKSPE-----------------------------------------------------PSADESPDNDKETQ----------------------------------------GGGGDAG-------KKRKRRVLFSKAQTYELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQNHRYKMKRARAEKGMEVTP---------------LPSPRRVAVPVLVRDGKPCH-----------ALKAQDLAAATFQAGIPFSAYS-AQSLQHMQYNAQ----YSSASTPQYPTAHPLVQAQQWTW--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95096-1", "uniprot_id": "NKX22_HUMAN", "id": "O95096-1", "name": "Homeobox protein Nkx-2.2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSLTN-------------TKTGFSVKDILDLPDTNDEEGSVAEGPEEEN-----EGPEPAKRAGPLGQG---------------------------------------------------------------------ALDAVQSLPLKNP------FYDSSDNPYTRWLASTEG-------------------------------------LQYS----------LHGLAAGAPPQDSSSKSPE-----------------------------------------------------PSADESPDNDKETP----------------------------------------GGGGDAG-------KKRKRRVLFSKAQTYELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQNHRYKMKRARAEKGMEVTP---------------LPSPRRVAVPVLVRDGKPCH-----------ALKAQDLAAATFQAGIPFSAYS-AQSLQHMQYNAQ----YSSASTPQYPTAHPLVQAQQWTW--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q90481-1", "uniprot_id": "NX22A_DANRE", "id": "Q90481-1", "name": "Homeobox protein Nkx-2.2a", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSLTN-------------TKTGFSVKDILDLPDTNDEEGSIT-GTEEDT-----EGSEATKTPGVLVQS---------------------------------------------------------------------PLENVQNLPLKNP------FYDNSDNPYTRWLATTDS-------------------------------------IQYS----------LHGLSANS--QDTSAKSPE-----------------------------------------------------PSADESPDNDKETS----------------------------------------SNGSDSG-------KKRKRRVLFSKAQTYELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQNHRYKMKRARAEKGMEVTH---------------LPSPRRVAVPVLVRDGKPCH-----------TLKAQDLAA-TFQAGIPFSAYS-AQSLQHMQYNAH----YSAATTPQFPTAHHLVQTQQWTW--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P22808-1", "uniprot_id": "VND_DROME", "id": "P22808-1", "name": "Homeobox protein vnd", "aln": "MTTSASLERTPSKRDRDRERDNSSGLGSAGSLPASPQSAITVSPSSPATPKRPLRTSTPSLERKREREDREDREDRKERQERHERDRDHERFAAVFSTASTTVPTNTSSSSGLAPEQLRIPTGAAAFSGFPGLHSMSSLMLPSSAAVAAAAAAPFLPWSPILLPPWNHALLPAAFYPAALRNALPGLFDAKVPSSQRSGFHISDILNLEGSELKNAAAAAAAAAHHGSDLSHHSASESTSGHRGQGSHTSPSALSPTPAGVSADEHHNGSGTGGGAGEADHHSTTEHHAPPSHPQQQHPHHQQHHHPHLLLPQQHHQQAVAPLPLAHHQSGEAQSHAHANAAAAHLLASHNAAAAAAVAAGQYLPNLPKNFPGSFGDEMSSYHHMAQTMLQHSGRSAWIKENELYGTQQPASPDSTSPVTSEVSYTYIGSNCQTSPALSGDYKSYSRSADSDALSVGDALHTLHGSSGNGSAGGAPTAHALHNNNNNTTNNNNHSLKAEGINGAGSGHDDSLNEDGIEEDIDDVDDADGSGGGDANGSDGLPNKKRKRRVLFTKAQTYELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQNHRYKTKRAQNEKGYEGHPGLLHGHATHPHHPSALPSPRRVAVPVLVRNGKPCLGDSSKLGADCVSVSSATATAMQNAAAHHLVALNGAAAYQHAAAAAAGLHAHAHAHAHAHGHGHPHAHAQRAAWWP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ::** :.***:* .:: ::.: : .. . . . . . .* *. : * *** : :: . :: **: :. :*:* *:* : :.:*. :.* *:*. :*:::* ..*.*:. *********:********************************************** ***: *** * **************:**** ::.: :* *. : * . * : ** * :: * : . .* .::*: :* ", "identical_positions": 117, "similar_positions": 76, "identity": "16.18%" }, { "cls_id": "homologset.agr.RGD:1308444", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q6UWM9-1", "uniprot_id": "UD2A3_HUMAN", "id": "Q6UWM9-1", "name": "UDP-glucuronosyltransferase 2A3", "aln": "-------MRSDKSALVFLLLQLFCVGCGFCGKVLVWPCDMSHWLNVKVILEELIVRGHEVTVLTHSKPSLIDYRKPSALKFEVVHMP-QDRTEENEI--FVDLALNVLPGLSTWQSVIKLNDFFVEIRGTLKMMCESFIYNQTLMKKLQETNYDVMLIDPVIPCGDLMAELLAVPFVLTLRISVGGNMERSCGKLPAPLSYVPVPMTGLTDRMTFLERVKNSMLSVLFHFWIQDYDYHFWEEFYSKALGRPTTLCETVGKAEIWLIRTYWDFEFPQPYQPNFEFVGGLHCKPAKALPKEMENFVQSSGEDGIVVFSLGSLFQNVTEEKANIIASALAQIPQKVLWRYKGKKPSTLGANTRLYDWIPQNDLLGHPKTKAFITHGGMNGIYEAIYHGVPMVGVPIFGDQLDNIAHMKAKGAAVEINFKTMTSEDLLRALRTVITDSSYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRSAAHDLTWFQHYSIDVIGFLLACVATAIFLFTKCFLFSCQKFNKTRKIEKRE-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0G2JW02-1", "uniprot_id": "A0A0G2JW02_RAT", "id": "A0A0G2JW02-1", "name": "glucuronosyltransferase", "aln": "MAGGRHTMVSVKWAVAIFLLQLCWSGCGICSKVLVWPCDMSHWLNLKTILEELAARGHEVTVLKYP-SIIIDQSKLTPLQFENIPVLYETEVAENHLNEIVNLAVNVIPNLSLWEAARTLQDFFLQLTGNFEDLCRSTLYNQTLMNKLRDAKYDVMVLDPVIPCGELVAEVLQIPFVNTLRFSMGYSMEKYCGQLPVPLSYVPVVMGELTDHMTFTERVKNMMLSLFFEFWLQQYDFAFWDQFYSKTLGRPTTFCKTVGKAEIWLIRTYWDIEFPRPYLPNFEFVGGLHCKPAKPLPKELEEFVQSSGEHGVVVFSLGSMIKNLTEEKANLIASALAQIPQKVLWRYSGKKPATLGPNTRILNWIPQNDLLGHPKTRAFITHGGTNGIYEAIYHGVPMVGIPMFGDQPYNIAHMEAKGAAVKVAINTMTSADLLSALRAVINEPSYKENAMRLSRVHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLSWFQYHSLDVIGFLLVCVVTLTFVITKCSLFMCRKCCLRERKKKGNRKKKN", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * * *:.::**** ***:*.**************:*.***** .********.:. . :** * :.*:** : : : .. **.: :*:**:**:*.** *::. .*:***::: *.:: :*.* :******:**::::****::*******:*:**:* :*** ***:*:* .**: **:**.******* * ***:*** ***** ***::*.**:*:**: **::****:******:*:***************:***:** ***************.****:*:*******.*:*******:::*:******:****************.****:***.***: :*************:******* ***************:*:**** *****:******:: ::**** *** ***:**.:.***********:***************************** *****:***::*:*******.**.* *::*** ** *:* .: :* : ", "identical_positions": 361, "similar_positions": 115, "identity": "66.61%" }, { "cls_id": "homologset.agr.RGD:1308445", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6ANG1-1", "uniprot_id": "A0A8I6ANG1_RAT", "id": "A0A8I6ANG1-1", "name": "", "aln": "MPFLHGFRRIIFEYQPLVDAILGALGIQDLERQEPLD--DYASSEESRILVLTELLEQKAHSPFYQEGVSNALLKMAELGLTRAAAVLLQSGANLNFEDPVTYYTALHIAVLRNQPDMVELLVRHGADINRRDRIHESSPLDLASEEPERLPCLQRLLDLGADVNAADKNG-----------------------------ADVKATTKDGDTVFTCIIFLLGETVCGDKEEAPMINRFCFQVTQLLLAHGADPSECPAH-------ESLTHICLKSFKLHFPLLRFLLESGAAYNCSLHGASCWSGFNLIFERLCSHP-GCAEDDSHVELLHKAETVLDLMVTSSQRLQ--LPEN-FNIHPVGGLAGKIQALHASLRQLESYPPPLKHLCRVSIRLCLRPWPVDTKVKALPLPDRLKWYLLSAHS-SPEDTC----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91ZU1-1", "uniprot_id": "ASB6_MOUSE", "id": "Q91ZU1-1", "name": "Ankyrin repeat and SOCS box protein 6", "aln": "MPFLHGFRRIIFEYQPLVDAILGALGIQDLERQEPLD--DSASSEESRILVLTELLEQKAHSPFYQEGVSNALLKMAELGLTRAAAVLLQSGANLNFEDPVTYYTALHIAVLRNQPDMVELLVRHGADINRRDRIHESSPLDLASEEPERLPCLQRLLDLGADVNAADKNGKTALLHALASSDGVQIHNTENIRLLLEGGADVKATTKDGDTVFTCIIFLLGETVCGDKEEAPMINRFCFQVTQLLLAHGADPSECPAH-------ESLTHICLKSFKLHFPLLCFLLESGAAYNCSLHGASCWSGFNLVFERLCSHP-GCAEDDSHIELLHKAETVLDLMVTSSQRLQ--LPEN-LNIHPVGSLAGKIQALHASLRQLESYPPPLKHLCRVSIRLCLRPWPVDTKVKALPLPDRLKWYLLSAHS-DTQDTC----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NWX5-1", "uniprot_id": "ASB6_HUMAN", "id": "Q9NWX5-1", "name": "Ankyrin repeat and SOCS box protein 6", "aln": "MPFLHGFRRIIFEYQPLVDAILGSLGIQDPERQESLDRPSYVASEESRILVLTELLERKAHSPFYQEGVSNALLKMAELGLTRAADVLLRHGANLNFEDPVTYYTALHIAVLRNQPDMVELLVHHGADVNRRDRIHESSPLDLASEEPERLPCLQRLLDLGADVNAADKHGKTALLHALASSDGVQIHNTENIRLLLEGGADVKATTKDGDTVFTCIIFLLGETVGGDKEEAQMINRFCFQVTRLLLAHGADPSECPAH-------ESLTHICLKSFKLHFPLLRFLLESGAAYNCSLHGASCWSGFHIIFERLCSHP-GCTEDESHADLLRKAETVLDLMVTNSQKLQ--LPEN-FDIHPVGSLAEKIQALHFSLRQLESYPPPLKHLCRVAIRLYLQPWPVDVKVKALPLPDRLKWYLLSEHSGSVEDDI----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BE57-1", "uniprot_id": "A0A8M2BE57_DANRE", "id": "A0A8M2BE57-1", "name": "", "aln": "MPFLHGFRRIVYEYQPLVDAVLCVLGT-DGENQRRQD------EEESVSVALAELLDREAQSPVFMQGISYSLFRVAEFGLVSAAQVLLRYGADLNFEDPVSYYNPLHIAVLRNKPDMVRMLISSGADIDKRDRIHESSPIDLASEEADKLPCLRVLLDFGADVNAKDKNGKTALLHALASSDGLTVKNMDNIQLLLERGADVNATTQDGETPMSSLAFLVKEALESSVEDAKEIGHFCTHVAHLLISHGAGPSCCLSATDGEVWEHSLTYTSLENFDLLFPLTVLLLQHSASFVCSHHSASYWTGPQLIFTRLAEALREAVDAAEVADVLAKAEVLLDLARICSPAIPPLFPRSQLPVLEQGSIHEPLLELYGKLEERESQPMPLRCLCRRLIRNCLLPWPFEEKVKALPLPDRLKDLLLPENSWKNRAGWDRFKPRGSSH", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**********::********:* ** * *.*. * .*** :.*:***:::*:**.: :*:* :*:::**:**. ** ***: **:*******:**..********:****.:*: ***:::*********:******.::****: ***:****** **:* ***:***:**:* ::.: **: *:: .. *:* *.:** :*::**::***.** * : .***: .*:.*.* *** :**: .*:: ** *.** *:* :::* **.. ..: . ::* ***.:*** * : :*.. : : *.: : *: .*.: ** * **: *** ** * ***.: ************ **. :* . . ", "identical_positions": 194, "similar_positions": 110, "identity": "43.89%" }, { "cls_id": "homologset.agr.RGD:1308446", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q2TGI8-1", "uniprot_id": "ZDH22_RAT", "id": "Q2TGI8-1", "name": "Palmitoyltransferase ZDHHC22", "aln": "----MLALRLLNVVAP----AYFLCISLVTFVLQLFLFLPSMREDPTATPLFSPAVLHGALFLFLSANALGNYILVVQNSPDDLGACQGTSSQRPQRPP-------------PSTHFCRVCARVTLRHDHHCFFTGNCIGSRNMRNFILFCLYTSLACLYSMVAGVAYISAVLS----------------ISFAHPLAFLTLLPTSISQF------FSGAVLGSDMFVILMLYLWFAVGLACAGFCCHQLLLILRGQTR-----------------YQVR-KGVAVRAR-PWRKNLQEVFGKRWLLGLLVP-------------------------------------MFNVG---TESSKQQDK-------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0PK84-1", "uniprot_id": "ZDH22_MOUSE", "id": "A0PK84-1", "name": "Palmitoyltransferase ZDHHC22", "aln": "----MLALRLLNVVAP----AYFLCISLVTFVLQLFLFLPSMREDPTATPLFSPAVLHGALFLFLSANALGNYVLVIQNSPDDLGTCQGTMSQRPQCPP-------------PSTHFCRVCSRVTLRHDHHCFFTGNCIGSRNMRNFILFCLYTSLACLYSMVAGVAYISAVLS----------------ISFAHPLAFLTLLPTSISQF------FSGAVLGSDMFVILMLYLWFAVGLACAGFCCHQLLLILRGQTR-----------------YQVR-KGMAVRAR-PWRKNLQEVFGKRWLLGLLVP-------------------------------------MFNVG---TESSKQQDK-------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N966-1", "uniprot_id": "ZDH22_HUMAN", "id": "Q8N966-1", "name": "Palmitoyltransferase ZDHHC22", "aln": "----MLALRLLNVVAP----AYFLCISLVTFVLQLFLFLPSMREDPAAARLFSPALLHGALFLFLSANALGNYVLVIQNSPDDLGACQGASARKTPCPS-------------PSTHFCRVCARVTLRHDHHCFFTGNCIGSRNMRNFVLFCLYTSLACLYSMVAGVAYISAVLS----------------ISFAHPLAFLTLLPTSISQF------FSGAVLGSEMFVILMLYLWFAIGLACAGFCCHQLLLILRGQTR-----------------HQVR-KGVAVRAR-PWRKNLQEVFGKRWLLGLLVP-------------------------------------MFNVG---SESSKQQDK-------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PSH3-1", "uniprot_id": "A0A8M1PSH3_DANRE", "id": "A0A8M1PSH3-1", "name": "Palmitoyltransferase", "aln": "MLFKMGKLKLLNTIAP----AYFYAATVVTFALHFLLFTPTIFQSSDVT-INPAMLAHISIFLFLMGNALGNYIMTIRN-PSESANETVIPVCSPDCPDRIDAHYLL-----NGRHFCKVCKKVILKRDHHCFFTGNCIGNRNMRYFIMFSIYTSSSCLYSLVIGVAYLTIEYS----------------ISFENPLTFLTLLPLSTGYF------FLGLISGLQFFLVIMLYIWLGIGLVSVGFCCQQLLLVARGQTW-----------------CELQ-KGQLSECRGTWRANLTDVFGSHWVLGLFVP-------------------------------------VPTVE---TVPGNWQVYHDHKHD-------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9I7L7-1", "uniprot_id": "Q9I7L7_DROME", "id": "Q9I7L7-1", "name": "Palmitoyltransferase", "aln": "-----MRFRSLKNIWPKEKLEQFLFLFILCGLPAIYYVLMEIILPELSDYWSPGYVFQLLLGLFLFSNVMSNYVMCILVDPSIDPKLMKNQLVRGQHSEDWHECDKCGILAPPRSRHCRKCGVCVLMRDHHCFFTGCCIGHENYRYFFYFLIYFFLSCMISLTSSSIFIYVLHGGRYQL-----------FMLTHPAPNSAYFNSLIIRI------IYFKLPDIYELVFTLVFVLLWIGVCVATYVAYDQWSRGYFCYD-----------------FELQNIPFDRKLRRNFKTFLGRRMKWTWISGFVPS-------------------------------------QLDHDGFDLDPDNERVADWCSETTIKDG--------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12006-1", "uniprot_id": "PFA4_YEAST", "id": "Q12006-1", "name": "Palmitoyltransferase PFA4", "aln": "--------MPVKLRWP------WLGIAIPTFLISFIGYGAHYFILSNFLSVPKQITFEFCLSMIWLSYYLAICTNPGRPLPNYKPPPDIWRNFCKKCQSYK----------PERSHHCKTCNQCVLMMDHHCPWTMNCVGFANYPHFLRFLFWIIVTTSVLFCIQAKRIYFIWQQRHLPGYFFKKSELIFLTISSPLNSFVLLTITILFLRCLFNQILNGRSQIESWDMDRLESLFNSGRLTQKLIDNTWRIYPESRSFQNKKDAEEHLTKKRPRFDELVNFPYDFDLYTNALLYLGPIHLWLWPYGVPTGDGNNFPKNGISKYEANSSLEDHILSLPWPPDGGKTNTVFNHGSSTIEMRNESGEQLIRTRLPQNGRHASREKWYNDWGESLDDFGVDVDME", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: * : : : . : :: . :. *. :.*: * * **** :* *:* * *. * :: : : : : : * . : : : . : : * :: * * *. : ", "identical_positions": 20, "similar_positions": 37, "identity": "4.98%" }, { "cls_id": "homologset.agr.RGD:1308448", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4A1H2-1", "uniprot_id": "D4A1H2_RAT", "id": "D4A1H2-1", "name": "", "aln": "------------------------------------------------------MASSQGKNELKFADWMATLPESIHSIPLTNLAIP-----GSHDSFSFYIDEA-------------------------------SPVGPEQPETVQNFVS--------------------------------------------------------------------------VFGTVAKKLMRKWLATQTMSFTGQLGAGIRYFDLRISTKPRDPDNELYFAHGLFSAKVNEGLEEINAFLTDHHKEVVF--LDFNHFYGMQKYHHEKLVQMLKDIYGNKMCPAIFA--QEVSLKYLWEKSYQVLVFYHSPVALEVPFLWPGQMMPAPWANTTDPEKLIQFLQAS--ITERRKKGSFFISQVVLTPKASTVVKGVASGLRETITERALPAMMQWIRTQKPG------ESGINIVTADFVELG--DFISTVIKLNYVFDEGEANT----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BLJ3-1", "uniprot_id": "PLCX3_MOUSE", "id": "Q8BLJ3-1", "name": "PI-PLC X domain-containing protein 3", "aln": "------------------------------------------------------MASSQGKNELKFADWMATLPESIHSIPLTNLAIP-----GSHDSFSFYIDEA-------------------------------SPVGPEQPETVQNFVS--------------------------------------------------------------------------VFGTVAKKLMRKWLATQTMSFTGQLGAGIRYFDLRISTKPRDPDNELYFAHGLFSAKVNEGLEEINAFLTDHHKEVVF--LDFNHFYGMQKYHHEKLVQMLKNIYGNKMCPAIFA--QEVSLKYLWEKDYQVLVFYHSPVALEVPFLWPGQMMPAPWANTTDPEKLIQFLQAS--ITERRKKGSFFISQVVLTPKASTVVKGVASGLRETITERALPAMMQWIRTQKPG------ESGINIVTADFVELG--DFISTVIKLNYVFNEGEANT----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63HM9-1", "uniprot_id": "PLCX3_HUMAN", "id": "Q63HM9-1", "name": "PI-PLC X domain-containing protein 3", "aln": "------------------------------------------------------MASSQGKNELKLADWMATLPESMHSIPLTNLAIP-----GSHDSFSFYIDEA-------------------------------SPVGPEQPETVQNFVS--------------------------------------------------------------------------VFGTVAKKLMRKWLATQTMNFTGQLGAGIRYFDLRISTKPRDPDNELYFAHGLFSAKVNEGLEEINAFLTDHHKEVVF--LDFNHFYGMQKYHHEKLVQMLKDIYGNKMCPAIFA--QEVSLKYLWEKDYQVLVFYHSPVALEVPFLWPGQMMPAPWANTTDPEKLIQFLQAS--ITERRKKGSFFISQVVLTPKASTVVKGVASGLRETITERALPAMMQWVRTQKPG------ESGINIVTADFVELG--DFISTVIKLNYVFDEGEANT----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q58EK3-1", "uniprot_id": "PLCX3_DANRE", "id": "Q58EK3-1", "name": "PI-PLC X domain-containing protein 3", "aln": "------------------------------------------------------MASSQGKSELRYADWMSSLPDTLHGIPLTNLAIP-----GSHDSFSFYIDEA-------------------------------SPVGPEQPETVQNFVS--------------------------------------------------------------------------VFGTVAKKLMRKWLATQTMNFTSQLEAGIRFFDLRISTKPRDPDNELYFAHGLFSATVREGLEQISTFLASHAREVVF--LDFNHFYGVQNLHHEKLVQMLRTVFGDRLCPVVFA--QEVSLKYLWEKEYQVLVFYHNPMALEVPFLWPGQMMPAPWANTTDPEKLILFLQAS--VKDRRRKGTFFVSQVVLTPKASTVMKGVTSGLRETITERALPSMMQWIRSQRPG------ESGVNIITADFVELG--EFISAVITLNYYLDDEEENAT---------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VIP3-1", "uniprot_id": "Q9VIP3_DROME", "id": "Q9VIP3-1", "name": "Phosphatidylinositol-specific phospholipase C X domain-containing protein", "aln": "---------------------------------------------------------------MSKDHWMRDLPSELRDLSIINLAIP-----GSHNSMTYGINSK-------------------------------SELSPDAEISIRRWHR--------------------------------------------------------------------------FFP----CFVRRWSKTQSSGTLDQLELGVRYFDLRIAQK----DDKFYYCHGLFAMEIFEPLLEIRQFVDTHPEEVVI--LDLQHFYAMTVAHHQKLHKDLIQFFAHRLYSTVDGSLKDCTLNRCLEMQRSVVIIYRRCPIPLPLRFWPSYAWPTPWPNKASVKKLQSFLEDS--LLSRQPQ-QGYVSQCLITPTGRYIAFRLFFTLKS-TAKRVDKKLQPWIQEQIPGPFEPKDEPRVNVFLADFVSLKGGQFCDWVVDLNTKLLEQLAGDKELESTEGVEEEEAQG", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VKC3-1", "uniprot_id": "Q9VKC3_DROME", "id": "Q9VKC3-1", "name": "", "aln": "MVGKVLRLALVLLLLASWTNEGRAQTESYENPKALKVWLTISARKRFLEVSWSNAPANKGDQLLVTREDALSFQSQLLRKHTPLAGFPSEEGSGSGDGSPSYVPNSGFTARPATKAASKEEEQEQYWVANGGATEVVAAIEPRQGLSTQWFTTGLPFDYALSRNATVQTACYGFWASYIDAQGNILAKTCLKVFPRWMNDLKSKIGEMRLRDLFIPGTHDSGSYRPNFDPLLRESLVTKYALTQDDDIRGQLMHGVRYLDIRVGYYRNSPDPFFIYHGITKQRPLQEVINQVRDFVYETNEIIIFGLKEFPVGFGKGLGVHRLLISYLRDQLKDLIAHPSLT--WGASLRDIWARRQNVFLAYDHEAMVEEFPDVLFGSVEQRWGNKQTWDQLETYLRNVNDFDVSRFSSRPVSDMAELTPETWDVILDKTGGLRKMADNVNWRISQLYRNELGTN---------ANIVSADFIRGT--TLVETAIEYNARKIYM--------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : . : .:* ** :. . : . : : * : : : . :: :: ** . .** *:*::*:*:. * : : : * : :: *: . ::: :: :. *. * . * . : :*. .*.: * * *. .:* :*. . : . . :** : *:. : : . .. *:. ***: : . .: * ", "identical_positions": 33, "similar_positions": 79, "identity": "6.41%" }, { "cls_id": "homologset.agr.RGD:1308449", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CHH9-1", "uniprot_id": "SEPT8_MOUSE", "id": "Q8CHH9-1", "name": "Septin-8", "aln": "---MAATDLERVSNAEPEPRSLSLGGHVGFDSLPDQLVSKS--------------------VTQGFSFNILCVGETGIGKSTLMNTLFNTTFET---------EEASHHEECVRLRPQTYDLQESNVHLKLTIVDAVGFGDQINKDDSYRPIVDYIDAQFENYLQEELKIRRSLFDYHDTRIHVCLYFITPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTISKSELHKFKIKIMGELVSNGVQIYQFPTDDEAVA----EINAVMNAHLPFAVVGSTEEVKVGNKLVR--ARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHSRHYELYRRCKLEEMGFQDSDGDSQPFSLQ----------------ETYEAKRKEFLSELQRKEEEMRQMFVNKVKETELELKEKERELHEKFEHLKRIHQEEKR----------------------KVEEKRRELEEETNAFNCRKAAMEALQSQALHATSQQPLRKDKDKKN------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B0BNF1-1", "uniprot_id": "SEPT8_RAT", "id": "B0BNF1-1", "name": "Septin-8", "aln": "---MAATDLERISNAEPEPRSLSLGGHVGFDSLPDQLVSKS--------------------VTQGFSFNILCVGETGIGKSTLMNTFFNTTFET---------EEASHHEECVRLRPQTYDLQESNVHLKLTIVDAVGFGDQINKDDSYRPIVDYIDTQFENYLQEELKIRRSLFDYHDTRIHVCLYFITPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTISKSELHKFKIKIMGELVSNGVQIYQFPTDDEAVA----EINAVMNAHLPFAVVGSTEEVKVGNKLVR--ARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHSRHYELYRRCKLEEMGFQDSDGDSQPFSLQ----------------ETYEAKRKEFLSELQRKEEEMRQMFVNKVKETELELKEKERELHEKFEHLKRIHQEEKR----------------------KVEEKRRELEEETNAFNCRKAAMEALQSQALHATSQQPLRKDKDKKK---VGGWSSIYSVTIP--------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q92599-1", "uniprot_id": "SEPT8_HUMAN", "id": "Q92599-1", "name": "Septin-8", "aln": "---MAATDLERFSNAEPEPRSLSLGGHVGFDSLPDQLVSKS--------------------VTQGFSFNILCVGETGIGKSTLMNTLFNTTFET---------EEASHHEACVRLRPQTYDLQESNVQLKLTIVDAVGFGDQINKDESYRPIVDYIDAQFENYLQEELKIRRSLFDYHDTRIHVCLYFITPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTISKSELHKFKIKIMGELVSNGVQIYQFPTDDEAVA----EINAVMNAHLPFAVVGSTEEVKVGNKLVR--ARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHSRHYELYRRCKLEEMGFQDSDGDSQPFSLQ----------------ETYEAKRKEFLSELQRKEEEMRQMFVNKVKETELELKEKERELHEKFEHLKRVHQEEKR----------------------KVEEKRRELEEETNAFNRRKAAVEALQSQALHATSQQPLRKDKDKKNRSDIGAHQPGMSLSSSKVMMTKASVEPLNCSSWWPAIQCCSCLVRDATWREGFL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q642H3-1", "uniprot_id": "SEP8A_DANRE", "id": "Q642H3-1", "name": "Septin-8-A", "aln": "---MAATDVDIFSNEE--KRNLSLGGHVGFDSLPDQLVSKS--------------------VTQGFCFNILCVGETGIGKSTLMNTLFNTMFEN---------EEASHYQNGVYLRPRTYDLQESNVHLKLTIVDTVGFGDQINKEESYKPIVDYIDTQFENYLQEELKVKRSLFNYHDTRIHICLYFISPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTISKSELHKFKIKIMSELVSNGVQIYQFPTDDEAVT----EINSSMNAHLPFAVVGSVEEVKVGNKTVR--ARQYPWGVVQVENESHCDFVKLREMLIRVNMEDLREQTHARHYELYRRCKLEEMGFKDTDPDSQPFSLQ----------------ETYEAKRKEFLGDLQKKEEEMRQMFVNKVKETEAELKEKERELHEKFEQLKRMHQEEKR----------------------KVEEKRRELEEEMNAFNRRKVAAETLSLSQP-------LKKDKDKKN------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A4FUM1-1", "uniprot_id": "SEP8B_DANRE", "id": "A4FUM1-1", "name": "Septin-8-B", "aln": "---MAATEVNTYPTEE--MRSLSLSGHVGFDSLPDQLVSKS--------------------VSQGFSFNILCVGETGIGKSTLMNTLFNTTFEN---------EEASHFHNGVHLRPRTYSLQESNVDLQLTIVDTVGFGDQVNKEESYKPIVDYIDAQFENFLEEELKIKRSLYNYHDSRIHICLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTVSKSELQKFKIKIMSELVSNGVQIYQFPTDDEAVA----EINSSMNAHLPFAVIGSSEEVKIGNKMVR--ARQYPWGVVQVENESHCDFVKLREMLIRVNMLDLREQTHARHYELYRRCKLEEMGFKDTDADSEPFSLQ----------------ETYVAKRREFIVELQMKEEQMRQMFVNKVKETEAELKEKERELHERFEMLKRTHQEEKR----------------------SLEEMRRDFEEEMNTFNRRKVAAETLQSLQGSTG----LKKDKEKKT------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P54359-1", "uniprot_id": "SEPT2_DROME", "id": "P54359-1", "name": "Septin-2", "aln": "----MSVEVDFVDKKEVHLRTLKQSGHVGFDSLPDQLVNKS--------------------VQNGFVFNVMCIGETGLGKSTLMDTLFNTSFES---------TPSPHTLPSVKLKAHTYELQESNVRLKLTICDTVGYGDQINKDDSFKAVVDYIDAQFENYLQEELKIKRSLVTCHDSRIHICLYFICPTGHGLKSLDLVCMKKLDSKVNIIPVIAKADTISKVELQRFKAKIIQELNANGVHIYQFPTDDETVA----ETNTSMNSHIPFAVVGSTEFIKVGNKLIR--ARQYPWGTVQVENETHCDFVKLREMLIRTNMEDMREKTHTRHYELYRQKRLEQMGFSDVDSDNKPISFQ----------------QTFEAKRSNHLAELQSKEEEVRQMFVQRVKEKEAELKESEKDLHAKFEKLKRDHAEEKR----------------------KLEESRKALEEDYLDFQRRKQQLATAHHTLT-------LGKSKKK--------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32458-1", "uniprot_id": "CDC11_YEAST", "id": "P32458-1", "name": "Cell division control protein 11", "aln": "-MSGIIDASSALRKRKHLKRGITFTVMIVGQSGSGRSTFIN----------------------------TLCGQQVVDTSTTILLP-----------------TDTSTEIDLQLREETVELEDDEGVKIQLNIIDTPGFGDSLDNSPSFEIISDYIRHQYDEILLEESRVRRNPR-FKDGRVHCCLYLINPTGHGLKEIDVEFIRQLGSLVNIIPVISKSDSLTRDELKLNKKLIMEDIDRWNLPIYNFPFDEDEISDEDYETNMYLRTLLPFAIIGSNEVYEMGGDVGTIRGRKYPWGILDVEDSSISDFVILRNALLISHLHDLKNYTHEILYERYRTEALSGESVAAESIRPNLTKLN---------------GSSSSSTTTRRNTNPFKQSNNINNDVLNPASDMHGQSTGENNETYMTREEQIRLEE--------------------------ERLKAFEERVQQELLLKRQELLQREKELREIEARLEKEAKIKQEE--------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q07657-1", "uniprot_id": "SHS1_YEAST", "id": "Q07657-1", "name": "Seventh homolog of septin 1", "aln": "MSTASTPPINLFRRKKEHKRGITYTMLLCGPAGTGKTAFANNLLETKIFPHKYQYGKSNASISSNPEVKVIAPTKVVSFNSKNGIPSYVSEFDPMRANLEPGITITSTSLELGGNKDQGKPEMNEDDTVFFNLIMTHGIGENLDDSLCSEEVMSYLEQQFDIVLAEETRIKRNPR-FEDTRVHVALYFIEPTGHGLREVDVELMKSISKYTNVLPIITRADSFTKEELTQFRKNIMFDVERYNVPIYKFEVDPEDDDLESMEENQALASLQPFAIITSDTRDSEGRYV-----REYPWGIISIDDDKISDLKVLKNVLFGSHLQEFKDTTQNLLYENYRSEKLSS-VANAEEIGPNSTKRQSNAPSLSNFASLISTGQFNSSQTLANNLRADTPRNQVSGNFKENEYEDNGEHDSAENEQEMSPVRQLGREIKQENENLIRSIKTESSPKFLNSPDLPERTKLRNISETVPYVLRHERILARQQKLEELEAQSAKELQKRIQELERKAHELKLREKLINQNKLNGSSSSINSLQQSTRSQIKKNDTYTDLASIASGRD-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : * :. : : ..: . . :. :. .:. . :. . :.. : :.: : * *:.::.. . . : .*: *:: * ** :::*. .* *:* .**:* ****.*:.:*: ::.:.. .*::*:*:::*:.:: ** : *: :: .: **:* * : * * : : ***:: * . * *:**** :.:::.. .*: *:: *: :: :::: *: ** ** *. . : . : . : ::: . : : . : :.: . . : . :. .. .: ", "identical_positions": 53, "similar_positions": 134, "identity": "9.48%" }, { "cls_id": "homologset.agr.RGD:1308450", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "J3QMK1-1", "uniprot_id": "J3QMK1_MOUSE", "id": "J3QMK1-1", "name": "", "aln": "MEYPGIEV-DAVTSGIQRRVKD-RIAKT-KLSVSLASKIKTKLFNNSSMFRISLKHNNRALARALSKEKENSRKITTEKMQLQKEVEKLNFENTFLRLKLNNLNEKLKEIESHVANNLLAAIETSSLSEFHQSSSFLSANKKQRRSNQCKSAHLPYERVLLTSENDDDDDDGADDKWNTKCSNRIISKTSPDTTSLVSRQPLSLHQCNLELFLPKEGNQKTCGSGHSEHTSS-VDVLPNESHCHSDQSPQ-SSPSEMKTGPSPNLRRGEKLTLKNITQRKKCVSS------TVDILYVSDLENQSISSPGSNWNNEINGHTNETSNNTQRNTECFLGLPSESSSEPYVKRMEQVQK-TDNFHFHNTVSEAADVELTATDVGKIVIVSK-SNKNQIKKKADCRKETFRKVKGASSDKKRESSKRECKDGSEVGAEKETDESRAKRGSGVLDGRGDSEEPNCISSTE-------QPSQVNTQKKITPQN---SSDQENIQNKKRRRTYMLDEQEEANPFSRHSVKFLQDGKFDLCQKTLHHNLSNPSRQTFVIHKSEKGNLFPNQEDKDTISESLEVTNEFHTADHSIR--ENVCDHEAQTTLGLRKSVN----AQQNLTK--KTKQKINRGTKIVSSMKQIYEDNDKD-MHFLEKGNFPFQTQADKVTTSGSLEATEEFDTPLFFTRVNGSLRDCETQNVMDLHKQITGIYPAQ-NESQMSKNPRQKVNRKTAVISGVNCFSSDKGVHCSEKDKS-FLLQKDKD-ILGTLKDLSESDMPALCNQDSAEP--YKSEMLLGLKKHDHDMQPACQGDSKVDKKLRKQANRKTEIISKITQIHDNDGGSAHDPLN-----------------------------------------------------------------KKLGQKVNIS-DIISQMNQLYETTIEDGNGFKSSVK-------------DCQGVISCDLGEINSNKKENYDPIQDPCTLVKKTKRKGSCNSGSSLAGDKNRCSLRLTDSSQVS-VTLDSGLRHHPNEADTSPGEWTNLPKKQKPIVVSS-PGDAFSVSAGKARSNPAKAVSEMTSKLKKRKTHLGCSPETHGPVEITPNTDLTKAVDSQQTEKENYLEKENYLENEKIAKRKPDFCMKVLKPLSQTCSSNIKNSSLDSMCKSSLPLSISSSKNLMLEESSSLESTCIFQVGDDAREKITAGTHNP-HRTQKSRPGSRTSLVLVDTSSVS-SNTANPENESEEQSSPPRRRKRQCAPLNLTEPSLKRQVWQRC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7TSY8-1", "uniprot_id": "SGO2A_MOUSE", "id": "Q7TSY8-1", "name": "Shugoshin 2A", "aln": "MEYPGIKV-DTVTSGIQRRVKG-RIAKT-NLNVSLASKIKAKILNNSSIFKISLKHNNRALARALSKEKENSRRITTEKMQLQKEVEKLNFENTFLRLKLNTLNKKLVEIESHVSNDLLTAIEISSLSEFHQGSFLLSATKKQRNSKQCKPAHLPYARVLLTSENDDD--DGADDKWQTKCNNRTISKTSPDSTSSVSRQPSSLHQCNLKAFPPKEDNQKTCGSGHLEHTSS-VDILPNES--HSDQSPK-SSLSEMKTAPSPSLRR-EKLSHGNVTMRKKCVSS------TPDILYVTDLDHQPTSSPGSNWNNEIHGHTNETSNNTQRNAECFLDLPSESSSEPDAKRMELVQKNTDSFHFQKTVYDAADMELTATDIGKIVAVSK-SKKNQNKKKADCRKETFRKVKGASSDKKRESSKRECKDGSEVGAEEEADAARAERGAGVLDGRGDSEEPNCISSTE-------QPSQVNTQKKRTLQN---SSDQENIQNTKRRQTYTTDEQEETNPFSRHSVKFLQDGKFDLCQKTLHHNLSKPSRQTFVIRKSEKDNLFPNQEDKDTISENLEVTNEFHIDDLSIEANENVCDHETQTMLDLKKSVS----AQQNQTKINKTKQKINRRTKIISVMSQVYEDNDKD-IHVLEKDNFPFHTQANKETTSGNLESSKEFESPLLFTRDNGSLRDCKTQNVLDLHKQIPDLYPDR-NESQISKIPRQKVNRKTEVISGVKCFSNDQGVHCSEKDKS-LLLQKDKD-FPGTLKDLSEFDTPAFCNKDSAKSCDYKSEMLLGLKKHDPNMQPACQDDSKAGKKLRQKVNRKTEIISKITQIHENDRGSTHDSLN-----------------------------------------------------------------KKLCQKVNIS-KIISQMNQIYETINEDGNGFKSSIK-------------DCEDIKSCDFGEINSNKKENYDPIQDPCTLVKKTKRKGSCKAGSSLAGAKNRCGLQLTDSSQVQSVPLDSGLRHHPNEADSGPGEQTNLPKMQKQSAGRS-LGDAFSVSLGKEGSRPAKAVSKMTPKSKKRKLPLGCSPETHGTVEITPNTDLAKAVDSQQTEKENYLEKE------KIAKRKPDFCTKVLKPLSETCSSNIKNSSLDSMCKSSLPLSISSRKTLMLEESSSLESTCIFQVGDAAHEKITTGTRNPHHRTQKSTPGSRTSLVLVDTSSVSDTNPANPENESEGQSSHPMRRKRQCVPLNLTEPSLRSKMRR--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZWI4-1", "uniprot_id": "D3ZWI4_RAT", "id": "D3ZWI4-1", "name": "", "aln": "MEYPGIED-DSVSSGIKRRVKD-RIAKT-KLNVSLASKIKTKILNNSSIFKISLKHNNRALARALSKEKENSRRITTEKVQLQKEVEKLNFENTFLRLKLNNLNKKLIEIESQVSNSLLTAIEMSSLSEFHQSSFLLSANKKKRVSKQCKPAHLPYARVLITSENDDDDDDGDDDKWKTKCNNRTVSKTSPDSTSSVSRQSLSLHQCNLEVFLPQEDNQKTCESGHSEYTSS-VDVLPNESHYHSDQSPK-SFLSKMKDAPSPSPIK-EKLSLGNVTKRKKCVSS------AADILHVADLDHQSISSPGSNWNNEINGCTNETSNNVQRNTECFPDLPSESSSGPNVKCMEQVQKNTDTFHLQKTVYEDADMELTATDIGKIVTISK-SNKSQNKKKADCRKETFRKVKGPSSDRKKERSKRKCKASSE-GAEGKTE-NRPERGSGVLDGRGDSEDPNCISNSE-------QPSQVNMQKEITFQK---SSDQENVQNQRRRQTYTTDEQEETNPFSRCSVKFLQDGKFDPYQNTLHCDLSKPSRQTFVIQTSEKDNLLPNQDNKENISENLEDANEFHIAHLSIKDNENVCDHETQTILDLKKNVN----AQQNQTKINKTKQKINRRTKIISITNQINEDNDKD-IHVLEKGNFPFQTQANKETTSGNLEASKEFETP-LYTRDSGSLHDCNTQNVLDLHKQITSIYPGQ-NKSQISKIPRQKLSRKTEVISEVNCFSNDRDVLCSEKDES-FLLQKDKE-IPGTLKDVSEFDKPAFYNKDSVKSCDFKAEPLLGLKRHDPNMPPACQADSKVDKKLRQKVKRKTEIISKINQIHKNDEGSAHDPLN-----------------------------------------------------------------KELRQKVSIS-KIISEMNQIYETINEDGNAFKSSLK-------------HCQDVMSCDFGKKTSNEEENHDLTPDLCSLVKKPRKKVSCKAGNSLTGDKNRCILQLTGSSQES-VTLDSGLKHGPNEADSGPGEQTNLPKKQKPSTVST-LGDAFSLSVVREGSHPAQTGSKVTSKSKKRKTPLRSS-DTRGAVERTPNTDGITAVYFQQTEKENYLENE------KIAKSKPDFRSKVLKPLSEICSSNIKNSSLGSMCESSVPLSTFSSKPLMLEESSSLDSTCIFPVGDGAHEKLKEGTPNP-RRTQKSRPGSRTSLVLVDNSSVS-SNTANPENESERHSSHQMRRKRQCTPLNLTEPSLRRQVLQYW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q562F6-1", "uniprot_id": "SGO2_HUMAN", "id": "Q562F6-1", "name": "Shugoshin 2", "aln": "MECPVMETGSLFTSGIKRHLKDKRISKTTKLNVSLASKIKTKILNNSSIFKISLKHNNRALAQALSREKENSRRITTEKMLLQKEVEKLNFENTFLRLKLNNLNKKLIDIEALMNNNLITAIEMSSLSEFHQSSFLLSASKKKRISKQCKLMRLPFARVPLTSNDDED-----EDKEKMQCDNNIKSKTLPDIPSSGSTTQPLSTQDNSEVLFLKENNQNVYGLDDSEHISSIVDVPPRESHSHSDQSSKTSLMSEMRNAQS-IGRRWEKPSPSNVTERKKRGSSWESNNLSADTPCATVLDKQHISSPELNCNNEINGHTNETNTEMQRNKQDLPGLSSESAREPNAECMNQIED-NDDFQLQKTVYD-ADMDLTASEVSKIVTVSTGIKKKSNKKTNEHGMKTFRKVKDSSSEKKRERSKRQFKNSSDVDIGEKIE-NRTER-SDVLDGKRGAEDPGFIFNNEQLAQMNEQLAQVNELKKMTLQTGFEQGDRENVLCNKK-EKRITNEQEETYSLSQSSGKFHQESKFDKGQNSLTCNKSKASRQTFVIHKLEKDNLLPNQKDKVTIYENLDVTNEFHTANLSTKDNGNLCDYGTHNILDLKKYVTDIQPSEQNESNINKLRKKVNRKTEIISGMNHMYEDNDKDVVHGLKKGNFFFKTQEDKEPISENIEVSKELQIPALSTRDNENQCDYRTQNVLGLQKQITNMYPVQQNESKVNKKLRQKVNRKTEIISEVNHLDNDKSIEYTVKSHSLFLTQKDKEIIPGNLEDPSEFETPALSTKDSGNLYDSEIQNVLGVK-HGHDMQPACQNDSKIGKKPRLNVCQKSEIIPETNQIYENDNKGVHDLEKDNFFSLTPKDKETISENLQVTNEFQTVDLLIKDNGNLCDYDTQNILELKKYVTDRKSAEQNESKINKLRNKVNWKTEIISEMNQIYEDNDKDAHVQESYTKDLDFKVNKSKQKLECQDIINKHYMEVNSNEKESCDQILDSYKVVKKRKKESSCKAKNILTKAKNKLASQLTESSQTS-ISLESDLKHITSEADSDPGNPVELCKTQKQSTTTLNKKDLPFVEEIKEGECQVKKVNKMTSKSKKRKTSIDPSPESHEVMERILDSVQGKSTVSEQADKENNLENE------KMVKNKPDFYTKAFRSLSEIHSPNIQDSSFDSVREGLVPLSVSSGKNVIIKENFALECSPAFQVSDDEHEKMNKMKFKVNRRTQKSGIGDRPLQDLSNTSFVS-NNTAESENKSEDLSSERTSRRRRCTPFYFKEPSLRDKMRR--", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** * :: . .:***:*::*. **:** :*.********:*::****:*:***********:***:******:*****: ********************.**:** :**: : *.*::*** ********.* :***.**:* *:*** :**: ** :**::*:* :** : :*.*. *** ** .* * * * : : :*.**:. .. *: ** **: *.** *****.: * *:*: . * : ** : *:* *** ** : * .: *::* *** * ****:* ****..: *** : : .*.***: * .: *: ::. .* *::::** : **::***:::.*** :*. :*.. **. : :******..**::*:* ***: * .*: . : : *.:* :.****: .:*:*. * ..* * :*** *: * *. ..*:**: :: .. :****: .:*: * ** *:.*** *::* : *:.*******:. **.**:***.:* .* *.*: :**** . * . *:**: ::. *.*:* *. ::** :: * ::*:** *:*:* .:: ****** :* *:*.** *:** :* . * .:* ::*:: * : ** . . * .****:.*:***..:** : *:*::.* ***:.*** :** *: :..*:.: : *..* :* ****: : *.*:* ** : **: .:** : : : :**:* *. :* **** *** .** * :. :*:***.: .**:.** ..** : ::* :**. . .***:***:** :*.: :* * .*:.: . . : .**::*. * * .:*** ::: **:: . *: **: :** *** . :.*:*.*:* ..***:.**: .:* * ** . * :. : . .: .::*.* **** : * ::: :* :: .:. :*::*** **:* *:.* **** *.::.**: *.**::**:.*: :. :*** * * ::::*. :*:.: * *.* :**:. . : :***** *.*. * :.* ** .*.*:.**:** ** *:*:*.*: :.****: :: : ", "identical_positions": 484, "similar_positions": 374, "identity": "37.61%" }, { "cls_id": "homologset.agr.RGD:1308451", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "O75362-1", "uniprot_id": "ZN217_HUMAN", "id": "O75362-1", "name": "Zinc finger protein 217", "aln": "MQSKVTGNMPTQSLLMYMDGPEVIGSSLGSPMEMEDALSMKGTAVVPFRATQEKNVIQIEGYMPLDCMFCSQTFTHSEDLNKHVLMQHRPTLCEPAVLRVEAEYLSPLDKSQVRTEPPKEKNCKE-NEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTHNGKSGARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVHTKKTAFGTSSAQTDSPQGGMPSSREDFLQLFNLRPKSHPETGKKPVR--CIPQLDPFTTFQAWQLATKGKVAICQ-EVKESGQEGSTDNDDSSSEKE------LG---------ETNKGSCAGLSQEKEKCKHSHGEAPSVDADPKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVHKKDRRAGAESPTMSVDGRQPGTCSPDLAAPLDENGAVDRGEGGSEDGSEDGLPEGIHLD---KNDDGGKIKHLTSSRECSYCGKFFRSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLRYHLERHHKEKQT-DVAAEVKNDGKNQDTEDALLTADSAQTKNLKRFFDGAKDVTGSPPAKQLKEMPSVFQNVLGSAVLSPAH-KDTQDFHKNAADDSADKVNKNPTPAYLDLLKKRSAVETQANNLICRTKADVTPPPDGSTTHNLEVSPKEKQTETAADCRYRPSVDCHEKPLNLSVGALHNCPAISLSKSLIPSITCPFCTFKTFYPEVLMMHQRLEHKYNPDVHKNCRNKSLLRSRRTGCPPALLGKDVPPLSSFCKPKPKSAFPAQSKSLPSAKGKQSPPGPGKAPLTSGIDSSTLAPSNLKSHRPQQNVGVQGAATRQQQSEMFPKTSVSPAPDKTKRPETKLKPLPVAPSQPTLGSSNINGSIDYPAKNDSPWAPPGRDYFCNRSASNTAAEFGEPLPKRLKSSVVALDVDQPGANYRRGYDLPKYHMVRGITSLLPQDCVYPSQALPPKPRFLSSSEVDSPNVLTVQKPYGGSGPLYTCVPAG-SPASSSTLEGKRPVSYQHLSNSMAQKRNYENFIGNAHYRPNDKKT-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LVZ2-1", "uniprot_id": "A0ABK0LVZ2_RAT", "id": "A0ABK0LVZ2-1", "name": "", "aln": "--------MPTQSLLVYMDGPEVLGSSLGTQMEVDDAVPMKGPAVVPFRAAQEKSLATAEGHMPLDCMFCSQVFSHAEDLNQHVLLQHRPTLCEPAVLRVEAEYLSPLDKGQVPTEPPKEKSSKEMEELSCDVCGQTFPVAFDVESHMKKHKDSFTYGCSMCGRRFKEPWFLKNHMRTHNGKSGTRSKLQQGTES-PVTINDVVQAHAPGNISTPYKICMVCGFLFPNKQSLIEHSKVHAKETVPSASSTAPDGHQEEPTSPREELLQFLNLRPRSTAESTVKPMT--SIPQLDPFTTYQAWQLATKGKVAVAQEEVKESGQEGSTDNDDSCSEKEELGEIWVGGKVEGSGKSKTNRSSCSGLSQDKDKSRHGNSEVPSGDADSKLPGSKEKPTHCSECSKAFRTYHQLVLHSRVHRKDRRADAPSPTMAGDARQPGTCSPELRTTLEESGAGDR-EGGSEDGSEDGLPEGLHLD---KNDDGGKAKPLTSSRECSYCGKFFRSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLRYHLERHHKDKQLGDAPAESKSEGRSQEPQDMLLTADSAQTKNLKRFLDGAKDVKGSPPAKLLKEMPSVFQSVLGSTVLSPAHNKDTQDFHKNAADG-AEKVRKSPAPAYLDMPRKK-TGDPRASSPACKLEG-VGPLAR-------EAGHGEK-MDREADYRHKPGADCQDRPLNLSLGALHACPAISLSKCLIPSIACPFCTFKTFYPEVLMMHQRLEHRYNPDTHKNCSSKSVLRNRRTGCPPALLGKDVPPLSGLHKPKAKPAFSSQAKALHPEKVRQGTSGPGKAPQTSGPDNSTLAPSNLKSHRSQPSAGGP-SATRQQQSELFPKGGVPAAMDKAKRPEPKLKAPPAPPAQSPLSSGNGNG------SAECPWGQQGRDYYCQRNAGSATSEYSEPHPKRLKSPVVSLDTEHPGPNGRRGFELPKYHVVRSITSLLPPEYVCSPPVLPPKARFLSPGEVESPSVLTVQKPYGASGPLYTCGPVG-HAGASPSLEGLTLCSLGWLQLNMRLLSHLSSGVKGVEQRWCPFLV-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E7EZ61-1", "uniprot_id": "E7EZ61_DANRE", "id": "E7EZ61-1", "name": "", "aln": "--------MPTHPLIPYVESPDGLGHDILS--HSSASMPGTGSSMTPHASLVEKPGILAESSLPLDCMFCEETFLHQEDLGPHLLSQHPTTFHGPAVLRVEAEFLTPGDRARSKTCPAVEK----NEELSCAVCGQAIKDATELETHMRKHKDSFTYCCSICGRRFKEPWFLKNHMRTHG---KTGSKSKNHELEIPATVNDVIQDQPPSPVVTSYKMCMVCGFFFHNKEALAEHSKVHNRDAEADENISTHDQPAEELPVSQHAFLQNLQLHPSVAREAEPKHPTGRWISQLDPFNTYQAWQLATRGKIAAGPNLAKELNADSNSDNEDSGSEKEELG---------------AIWASGDKPARRGLRSELKPSDTPSPSPEQKGLIRKDKPTNCEECGKIFRTYHQLVLHSRIHKKER-GGAESPTTPVDGRAQSVGS-------CSSSSLDRADEYSEDGSEEGVPVDAFNPDKLEDGQGKMKLKILAPRKCNYCGKTFRSNYYLNIHLRTHTGEKPYKCEYCDYAAAQKTSLRYHLDRRHKDKPFTEIPN----------------IPATPSARNIIKAIEPPKNVDNKQASKPPKQWLAPKP--LPASVKHELGTSQVIKSTSPSIQVKQEFVSSPVATPYTPLSEDNKKYPLPAN-------------------------------------LKMEEKEASEAPLNLSLKVSLSISATSVPRNLLLTNTCTSCSYETLYPEVLLMHKKLIHKQNLDIKKNGYRGPQKLKRYTGCPPALEGKDVAPLAHINRRHPRRTKSP---------LRQPPEKLQKPPQMSKVSPVKERWRDQHRGRELDATNLLPRKPEQESSRKFN------VPSVIDRELPKQKPVLDHEMNQRMGKNGMVWP-----------TDPARLCLSDRFRNLTQMEVGEPSSKRQKS---FEPLHTASGRLGEDFNRLVPSGRNAKTSLQTHSPLASIKVTPTASSNSMQPDWNVMNMLRTYTPNNLASLYHPIAPSSSHGVMSSPVSGSRSLIFPQYSTSMSQRRIQSSPLNNERCGGPSDKSS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***:.*: *::.*: :* .: : . . ::. .*.::.*. : ** *. :*******.:.* * ***. *:* ** .*: *********:*:* *:.: * *. ** :*:** ****:: * ::* **:.******* *.:******************. : ** :: . *.*:*:*:* :.. : :.**:******:* **::* ** *** :.: . . : * . .:. :** ::*:* *: * *.*****.*:*******:**:* .** . :..:**:** **** : .* :: :.. .:.** ..: * *:***:*.**.* ************:*:*:* ..* *** . *.* .. * ...: ** : ******:*:* . . ::.:* : :.*:*.**** ***********************:*:*************:*:**:* : . . :..::*: : :: .*:* .. .:* *: : * ::* .:. . . : : : * . :..* : ... *. :. : *****: . .* *:.: *: : :*. *:::*:*****:**::* *: * * :** . .* ******* ****.**: : : :.: : .. :* . *.* * . . : : * .. ..*:.*. * . . .* .* *. : :.... .* .:* . : * .** .** ** . .. . ..:: .. *** . . : . . *. . : : .:* . .* . :. :. * . *..:.* . .* .. : . . ", "identical_positions": 310, "similar_positions": 288, "identity": "28.86%" }, { "cls_id": "homologset.agr.RGD:1308452", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q3KR97-1", "uniprot_id": "BI2L1_RAT", "id": "Q3KR97-1", "name": "BAR/IMD domain-containing adapter protein 2-like 1", "aln": "MSRGPEEVNRLTENTYRNVVEQFNPGLRNLINLGKNYEKAVNAMILAGKAYYDGVAKIGEIATGSPVSTELGHVLIEISSTHKKLNETLDENFKKFHKEIIHELEKKTELDVKYMNATLKRYQAEHRNKLDSLEKSQAELKKIRRKSQGGRNALKYEHKEIEYVETVTSRQSEIQKFIADGCKEALLEEKRRFCFLVDKHCSFASHIHRYHLQSAELLNSKLPRWQETCCDATKVP-------EKIMNMIEEIKTPISTPVSGTPQPSPMTERSKMIGKDYDTLSKYSPKMPPAPSVKAYTSPLIDMFNNPATAGQSAEK--------------------TNNSTANTGDDPSLQRSVSVATGLNMMKKQ-KVKTIFPHTAGNNKTLLSFAQGDVLTLLIPEEKDGWLYGEHDTTKVRGWFPSSYT----------------------------------------------------------------------------------KLLEENMKEAMSVPTPSSAPVRSISTVDLTEK----SSVVIPPPDYLECLSMGATSDKRADAAKIPSTSTFKAPVPRPDATSTSPSDSNGTAKPPFLSGENPFATVKLRPTVTNDRSAPIIR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DBJ3-1", "uniprot_id": "BI2L1_MOUSE", "id": "Q9DBJ3-1", "name": "BAR/IMD domain-containing adapter protein 2-like 1", "aln": "MSRGPEEVNRLTENTYRNVMEQFNPGLRNLINLGKNYEKAVNAMILAGKAYYDGVAKIGEIATGSPVSTELGHVLIEISSTHKKLNETLDENFKKFHKDIIHELEKKTELDVKYMNATLKRYQAEHRNKLDSLEKSQAELKKIRRKSQGGRNALKYEHKEIEYVETVTSRQSEIQKFIADGCKEALLEEKRRFCFLVDKHCSFASHIHYYHMQSAELLNSKLPRWQETCCDATKVP-------EKIMNMIEEIKTPISTPVSGTPQPSPMIERSKMIGKDYDTLSKYSPKMPPAPSVKAYTSPLIDMFNNPATAAQSSEK--------------------TNNSTANTGEDPSLQRSVSVATGLNMMKKQ-KVKTIFPHTAGNNKTLLSFAQGDVLTLLIPEEKDGWLYGEHDTTKARGWFPSSYT----------------------------------------------------------------------------------KLLEE--NEAMSVPTPSPAPVRSISTVDLTEK----SSVVIPPPDYLECLSMGATSDKKAGAPKVPSASTFRAPVSRPDATSTSPSDANGTAKPPFLSGENPFATVKLRPTVTNDRSAPIIR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UHR4-1", "uniprot_id": "BI2L1_HUMAN", "id": "Q9UHR4-1", "name": "BAR/IMD domain-containing adapter protein 2-like 1", "aln": "MSRGPEEVNRLTESTYRNVMEQFNPGLRNLINLGKNYEKAVNAMILAGKAYYDGVAKIGEIATGSPVSTELGHVLIEISSTHKKLNESLDENFKKFHKEIIHELEKKIELDVKYMNATLKRYQTEHKNKLESLEKSQAELKKIRRKSQGSRNALKYEHKEIEYVETVTSRQSEIQKFIADGCKEALLEEKRRFCFLVDKHCGFANHIHYYHLQSAELLNSKLPRWQETCVDAIKVP-------EKIMNMIEEIKTPASTPVSGTPQASPMIERSNVVRKDYDTLSKCSPKMPPAPSGRAYTSPLIDMFNNPATAAPNSQR--------------------VNNSTG-TSEDPSLQRSVSVATGLNMMKKQ-KVKTIFPHTAGSNKTLLSFAQGDVITLLIPEEKDGWLYGEHDVSKARGWFPSSYT----------------------------------------------------------------------------------KLLEENETEAVTVPTPSPTPVRSISTVNLSEN----SSVVIPPPDYLECLSMGAAADRRADSART--TSTFKAPASKP--ETAAPNDANGTAKPPFLSGENPFATVKLRPTVTNDRSAPIIR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AYE5-1", "uniprot_id": "A0A8M3AYE5_DANRE", "id": "A0A8M3AYE5-1", "name": "BAR/IMD domain-containing adapter protein 2-like 1", "aln": "MSRDPDEVNKLTESTYKNVMEQFNPGLRNLINLGKSYEKAVSAMVLAGKQYFDAVSKIGENAAVSPVSRELGVVLMEISDVHRKVNVELEENFRRFHREVIAELERKTDMDVKYMTATFKRYQTEHKMKQDSLERSQSDLKKVRRKSQG-RNASKYESKENECLETLTHRQMDMQKFIADGCQEALLEEKRRFCFLVDKHCSFSHQVSAFHQKARELLSDNLIVWQEKCSDATNVP-------DSVLSMIEGLR----TPVSNTPQPSPSLQRHSRVRAN-------SEAMIPAPPAPPQTSPLANMFS------QQSSR--------------------PDSDSDYLNEDSGLSRSVSMATGLNHIDKRPKVRTIFPHKSGNNSTLLSFEEGDIITLLIPDERDGWLYGELNNTRQRGWFPSSYC----------------------------------------------------------------------------------RAYTEPAVNNSMVGLP---PMRSKSVANLMQQEPAEDRMVLPPADY------GDSPVRRNSTKSLTQTYTPSLENSGP--------QSNGLPKHPLLGGGNPFATVKLRPTVTNDRSAPII--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IQE6-1", "uniprot_id": "Q8IQE6_DROME", "id": "Q8IQE6-1", "name": "", "aln": "--MEAEEVTKLVDGVYRNILDRFNPGARQLIAAGKSYLKALHGAATASRLFNEALAKIAMNAQQSGTG-DIGSALMSVVNVNKEIQDQQMNILKAFYVDLLVPLETNLEKDTKVVQHEQKKFLQQHKVRMESYQKAVSTMKKQRK----KKATPENTEKELRSLQLLEDQKKKLDVFCDQSYKNAMTQERRRYGFVLERQCSIAKHWMVYHTTGKTVIDNNFENWQEIAASREIIPPAAYESGYSTSNGHNNNNISSSSSSGNNNTSGNMRRLERIKDGDDDHLQGHGAQLKKSRSIDAPYGDMRTLHERENLSGLGGTGPAHYAQNSLPRAKSDFNLALVGTGQSSANKHKIIEEQLATLGDDQRGDQRPLVKALYAYMP-SGENQLSFEEGDRIALVG-GKAKGWQFGENLRTQHFGWFPVAYTNAEVAEVTTSGGRRYENMLMSYERNGGGSGSGSGGGGLRSYQQQQDYEAQLELMESHEATYRRRRNHSAEDSSPTRMFGDTIKQQKKYRPGSGANPRPGPPPTLPAPVPNGPQSQS--SRMLNSSQSFCASNGGGVNAAVERRKQKLLNGVQSSKNHPSGKSGVAAKTSLHSSNDSGFANEPPPQPEVDYSDEEPATQRVAIRRRADTNSHTNTVPRDVASWTLNRNFRNSVDSQIDDKSLHRLSRQSGGVGKMRYDLIASDDEILQASSAGLKRTKSFWKFGGGRNGEDILAGMSLWQHRDLVAAPNLEEMRDRDDLERRLEEDRNGTLTKSHNSSSSQEKRERKDSLTSTELYGDEDENIYGVSPQQPPLQQQTQQHQQHQQHQQQQAQQHRSSYTPKSRMKIMKTIEIDIEEPTEAERMSTMRRGQSQDQQQQHRKLDKQVSGTGSQHKSLTLSRTKSNQQQQQQQQFPQSTDEGESDEHGTLKLSDVNNFFDGEGKNNSHGHGLVMKTVKRQDILKQYYTSEDEEDSDAELKSTSSDPYDCIVINDHLVRKDDKMRRHHQQQHQQMATNTLKKSSSKDQDSTLTRNSTASSGAPTATILPRTRLLKSSTSAGNNIGNSSATLERNSKGLAGNKSYGPWYDFWDQEQHGQKSASAKLK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:**.:*.:..*:*::::**** *:** **.* **: . *.: : :.::**. * * .. ::* .*:.: ..::::: : :: *: ::: ** : : *.* : *:: :*: : :* ::: : :** *: : : : ** . :: : :: .:: * :. ::*: :*:**: *:::::*.:: : :* . ::..:: *** . . :* . . : . :. ... .. . : . : : . . . : :.. . ... ... :...:: . : .:: *::::.: . .... *** :** ::*: : .** :** :: **** :* : : * * . .. : :. . :: .. .: * . . . . :. . : . * . *. . : ..* ", "identical_positions": 71, "similar_positions": 195, "identity": "6.53%" }, { "cls_id": "homologset.agr.RGD:1308453", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P62878-1", "uniprot_id": "RBX1_MOUSE", "id": "P62878-1", "name": "E3 ubiquitin-protein ligase RBX1", "aln": "MAAAMD-VDTPS--------GTNSG----AGKKRFEVK--KWNAVALWAWDIVVDNCAICRNHIMDLCIECQANQASATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62877-1", "uniprot_id": "RBX1_HUMAN", "id": "P62877-1", "name": "E3 ubiquitin-protein ligase RBX1", "aln": "MAAAMD-VDTPS--------GTNSG----AGKKRFEVK--KWNAVALWAWDIVVDNCAICRNHIMDLCIECQANQASATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0G2JUC8-1", "uniprot_id": "A0A0G2JUC8_RAT", "id": "A0A0G2JUC8-1", "name": "E3 ubiquitin-protein ligase RBX1", "aln": "MARELV-TEAAA--------EILTSLLCYPENALFPLFSLQWNAVALWAWDIVVDNCAICRNHIMDLCIECQANQASATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9W5E1-1", "uniprot_id": "RBX1A_DROME", "id": "Q9W5E1-1", "name": "RING-box protein 1A", "aln": "MEVDEDGYEVPS--------SSSKG-----DKKRFEVK--KWNAVALWAWDIVVDNCAICRNHIMDLCIECQANQASATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWDFQKYGH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08273-1", "uniprot_id": "RBX1_YEAST", "id": "Q08273-1", "name": "RING-box protein HRT1", "aln": "MSNEVDRMDVDEDESQNIAQSSNQSAPVETKKKRFEIK--KWTAVAFWSWDIAVDNCAICRNHIMEPCIECQPKAMTDTDNECVAAWGVCNHAFHLHCINKWIKTRDACPLDNQPWQLARCGR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :. . : * : :*.***:*:***.************: *****.: : *.:**..**********:***.:*:***:.*****: *:: : *:", "identical_positions": 54, "similar_positions": 29, "identity": "43.9%" }, { "cls_id": "homologset.agr.RGD:1308454", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q925S8-1", "uniprot_id": "YMEL1_RAT", "id": "Q925S8-1", "name": "ATP-dependent zinc metalloprotease YME1L1", "aln": "MFSLSSTVQPQVTVPLSHLINAFHSPKNISVSVNTSASPKQHRDTVAEHEAPSSEPVLNLRDLGLSELKIGQIDKLVENLLPGFYKDKRVSSCWHTSHISAQSFFENKYGHLDMFSTLRSSSLYRQHPKTLQSICSDLQNFPVFIQSRGFKTLKSRTRRLQSTSERLAEAQNIAPSFVKGFLLRDRGTDLESLDKLMKTKNIPEAHQDAFKTGFAEGFLKAQALTQKTNDSLRRTRLILFVLLLFGIYGLLKNPFLSVRFRTTTGLDSAVDPVQMKNVTFEHVKGVEEAKQELQEVVEFLKNPQKFTVLGGKLPKGILLVGPPGTGKTLLARAVAGEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIEFPMHPYSRQTIIQLLAEMDGFKPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPDVKGRTEILKWYLNKIKFDKSVDPEIIARGTVGFSGAELENLVNQAALKAAVDGKEMVTMKELEFSKDKILMGPERRSVEIDNKNKTITAYHESGHAIIAYYTKDAMPINKATIMPRGPTLGHVSLLPENDRWNEIRAQLLAQMDVSMGGRVAEELIFGTDHITTGASSDFDNATKIAKRMVTKFGMSEKLGVMTYSDTGKLSPETQSAIEQEIRILLRESYERAKHILKTHAKEHKNLAEALLTYETLDAKEIQIVLEGKKLEVR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B2RU33-1", "uniprot_id": "POTEC_HUMAN", "id": "B2RU33-1", "name": "POTE ankyrin domain family member C", "aln": "------MVTEVCSMPAASAVKKPFDLR------SKMGKWFHHRFPCCKGSGKSNMGTSGDHDDSFMKMLRSKMGKCCHHCFP---------CCRGSGTSNVGTSGDHDNSFMKTLRSKMGKWCCHCFPCCRGSGKSNVGAWGDYDDS---AFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKQKRTALHLASANGNSE---VVQLLLDRRCQLNVLDNKKRTALIKAVQCQE-----DECVLMLLEHGADQNIPDEYGNTTLHYAVHNEDKLMAKALLLYGADIESKN----------KCGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVNLLLEQNVDVS------SQDLSGQTAREYAVSSH-HHVICELLSDYK----EKQMLKISSENSNPEQDLKLTSE---EESQRLKVSENSQPEKMSQEPEINKDCDREVEEEIKKHGSNPVG--LPENLTNGASAGNGDDG-----------------LIPQRRSRKPENQQFPDTENEE----------------------------------YHSDEQNDTRKQLSEEQNTGIS----------QDEILTNKQKQIEVAEKKMN---SELSLSHKKEEDLLREN--------SMLQEEIAMLISGDWN-------------------------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ::* : :: .. : .. .. :** . .: .. *. . . :* .: :: .::.* .: :* .* :. .. : ::. ..:. : : .. : .* * *:: : : :* ::.* : :. ::* .* . *.::: *.**::. ** :* : :. : . :* : :. *. :** ** * : :: :.. : .: . . . :: ...:. * : :* :* : * **:* : :: : :*:: * : * *:: * **: * :.:.. . * * . *:.: .: ::.* :**:: . :: :: *.: * * * : . : .: . :: : : . *:.*: ** :*: .. ***.* *: . ** : *:*** : :*:: . * .* ..*. *: * ** : :..:. *.* *. ..::: * * : :::.:*.* :. * :::** :*: .:: ", "identical_positions": 90, "similar_positions": 210, "identity": "12.59%" }, { "cls_id": "homologset.agr.RGD:1308455", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A1Z5-1", "uniprot_id": "A0A8I6A1Z5_RAT", "id": "A0A8I6A1Z5-1", "name": "Thioredoxin-related transmembrane protein 1", "aln": "MHGNKSTSLFPSPPSARGQDPDMRTELLGGVGLARLAGSLCAWAERPPERKWSCGGAVGRERSETGQVADMAHLGRLLVPLAALVLLLWAVPGAHGRRSNVRVLTDENWTSLLEGEWMIEFYAPWCPACQNLQPEWESFAEWGEDLEVKVAKVDVTEQTGLSGRFIITALPSIYHCKDGEFRRYLGPRTKKDFINFISEKEWKNVEPVSSWFGPSSVLMTTMSALFQLSVYIRTSHSYFVHDLG-------IPAWGSYLVFAFATVLSGLLLGLCMIFVADCLCPSKRRRPQ--QQPTKKPSP--------------------EFSQPLKKVEEEQEADEEDVSEEETENREGESKDTPQSGLRQRCVGPSSATDKS----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VBT0-1", "uniprot_id": "TMX1_MOUSE", "id": "Q8VBT0-1", "name": "Thioredoxin-related transmembrane protein 1", "aln": "----------------------------------------------------------------------MAHLGRLMVPLAALVLLLWAVPGAHGRRNNVRVLTDENWTSLLEGEWMIEFYAPWCPACQNLQPEWESFAEWGEDLEVKVAKVDVTEQTGLSGRFIITALPSIYHCKDGEFRRYVGPRTKKDFINFVSDKEWKNIEPISSWFGPSSVLMTMMSALFQLSVYIRTSHSYFVHDLG-------IPAWGSYLVFAFATVLSGLLLGLCMIFVADCLCPSKRRKPQ--QQYAKKTSP--------------------EFSQPLKKVEEEQEADEEDVSEEEAEDREGASKATSQSSIRQRCVGLPSATDTS----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H3N1-1", "uniprot_id": "TMX1_HUMAN", "id": "Q9H3N1-1", "name": "Thioredoxin-related transmembrane protein 1", "aln": "----------------------------------------------------------------------MAPSGSLAVPLAVLVLLLWGAPWTHGRRSNVRVITDENWRELLEGDWMIEFYAPWCPACQNLQPEWESFAEWGEDLEVNIAKVDVTEQPGLSGRFIITALPTIYHCKDGEFRRYQGPRTKKDFINFISDKEWKSIEPVSSWFGPGSVLMSSMSALFQLSMWIRTCHNYFIEDLG-------LPVWGSYTVFALATLFSGLLLGLCMIFVADCLCPSKRRRPQPYPYPSKKLLS--------------------ESAQPLKKVEEEQEADEEDVSEEEAESKEGTNKDFPQNAIRQRSLGPSLATDKS----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4LHC9-1", "uniprot_id": "A0A0B4LHC9_DROME", "id": "A0A0B4LHC9-1", "name": "Thioredoxin-related transmembrane protein 1", "aln": "---------------------------------------------------------------MHSTSYFVAATCAALLLLAATAQSTAAAQSGLQPGGKLIELDEDNWHLMLQGEWMIEFFAPWCPACKNLAPTWERFARVAKDVQVQVAKIDVTTSPSLSGRFFVTALPTIYHVKDGEFRQYRGARDGDALLYFVKKQQWQSIEPLSAWKKPDTTHMSVLSYFFKLSHTLKHTQKLFKDFNGRLQEEYGLPTWGSYALFAIATIFVGAALGLLLVCLVDFVYPPKKSQRQSFSESQDNLTEGLEDLATEEIEDDGDAEENDDEQRDSDEEEQEDDDEEEEDSEEQVGDLATKEKEADSEPEKEEKPEPKQAGDAAPEKTEQVRKRKPRKGD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* : **. . .. .:: : ::** :*:*:*****:*******:** * ** **. .:*::*::**:*** ...*****::****:*** ******:* *.* . :: *:..::*:.:**:*:* *.:. *: :* :*:** :: :. * . * :*.**** :**:**:: * *** :: :.* : *.*: : * .: : : .: *:*:: :**: ***:. . .* .. ::. * * : ", "identical_positions": 95, "similar_positions": 93, "identity": "24.17%" }, { "cls_id": "homologset.agr.RGD:1308456", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4A934-1", "uniprot_id": "D4A934_RAT", "id": "D4A934-1", "name": "Kin of IRRE-like protein 2", "aln": "---MLASALLVVLCCFR----------------------------------------------------------GNAGSSPHFLQQPEDMVVLLGQEARLPCALGAYRGLVQWTKDGLALGGERDLPGWSRYWISGNSASGQHDLHIKPVELEDEASYECQAS-----QAGLRSRPAQLHVMVPPEAPQVLGGPSVSLVAGVPGNLTCRSRGDARPAPELLWFR--DGIRLDGTSFHQITLRDKATGTVENTLFLTPSSQDDGATLICRARSQALPTGRDTAVTLSLQYPPMVTLSAEP-----QTAQEGEKVTFLCQATAQPPVTGYRWAKGGSPVLGARGPRLEVV-ADATFLTEPVSCEVSNAVGSANRSTALEVLYGPILQAKPKPVSVDVGKDASFSCVWRGNPLPRISWTRLGGSQVLSSGPTLRLPSVALEDAGDYVCRAEPRRTGVGGGTAQARLTVNAPPVVTALHPAPAFLRGPARLQCVVFASPAPDSVVWSWDEGFLEAGSLGRFLVEAFPAPEVEGGQGPGLISVLHISGTQESDFTTGFNCSARNRLGEGRVQIHLGRR-DLLPTVRLVAGAASAATSLFMVITGVVLCCWRHG------------------SLSKQKNLVR-----------------------------IPGSSEGSSAHGPEEE-TGSSEDRGP---IVHTDHNDLVLEENEALETKDPTNGYYKVRGVSVSLSLGEAPGGGLFLPPPSPMGLPGTPTYYDFKPHLDLVPP--------------------CRLYRARAGYLTTPHPR--------------------AFTNYMKPTSFGPPDLSSGTPPFPYATLSPPSHQR--LQTHV--------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TSU7-1", "uniprot_id": "KIRR2_MOUSE", "id": "Q7TSU7-1", "name": "Kin of IRRE-like protein 2", "aln": "---MLASALLVFLCCFK----------------------------------------------------------GHAGSSPHFLQQPEDMVVLLGEEARLPCALGAYRGLVQWTKDGLALGGERDLPGWSRYWISGNSASGQHDLHIKPVELEDEASYECQAS-----QAGLRSRPAQLHVMVPPEAPQVLGGPSVSLVAGVPGNLTCRSRGDSRPAPELLWFR--DGIRLDGSSFHQTTLKDKATGTVENTLFLTPSSHDDGATLICRARSQALPTGRDTAVTLSLQYPPMVTLSAEP-----QTVQEGEKVTFLCQATAQPPVTGYRWAKGGSPVLGARGPRLEVV-ADATFLTEPVSCEVSNAVGSANRSTALEVLYGPILQAKPKSVSVDVGKDASFSCVWRGNPLPRITWTRMGGSQVLSSGPTLRLPSVALEDAGDYVCRAEPRRTGLGGGKAQARLTVNAPPVVTALQPAPAFLRGPARLQCVVFASPAPDSVVWSWDEGFLEAGSLGRFLVEAFPAPEVEGGQGPGLISVLHISGTQESDFTTGFNCSARNRLGEGRVQIHLGRR-DLLPTVRIVAGAASAATSLLMVITGVVLCCWRHG------------------SLSKQKNLVR-----------------------------IPGSSEGSSSRGPEEE-TGSSEDRGP---IVHTDHSDLVLEEKEALETKDPTNGYYRVRGVSVSLSLGEAPGGGLFLPPPSPIGLPGTPTYYDFKPHLDLVPP--------------------CRLYRARAGYLTTPHPR--------------------AFTSYMKPTSFGPPELSSGTPPFPYATLSPPSHQR--LQTHV--------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6UWL6-1", "uniprot_id": "KIRR2_HUMAN", "id": "Q6UWL6-1", "name": "Kin of IRRE-like protein 2", "aln": "MLRMRVPALLVLLFCFR----------------------------------------------------------GRAGPSPHFLQQPEDLVVLLGEEARLPCALGAYWGLVQWTKSGLALGGQRDLPGWSRYWISGNAANGQHDLHIRPVELEDEASYECQAT-----QAGLRSRPAQLHVLVPPEAPQVLGGPSVSLVAGVPANLTCRSRGDARPTPELLWFR--DGVLLDGATFHQTLLKEGTPGSVESTLTLTPFSHDDGATFVCRARSQALPTGRDTAITLSLQYPPEVTLSASP-----HTVQEGEKVIFLCQATAQPPVTGYRWAKGGSPVLGARGPRLEVV-ADASFLTEPVSCEVSNAVGSANRSTALDVLFGPILQAKPEPVSVDVGEDASFSCAWRGNPLPRVTWTRRGGAQVLGSGATLRLPSVGPEDAGDYVCRAEAGLSGLRGGAAEARLTVNAPPVVTALHSAPAFLRGPARLQCLVFASPAPDAVVWSWDEGFLEAGSQGRFLVETFPAPESRGGLGPGLISVLHISGTQESDFSRSFNCSARNRLGEGGAQASLGRR-DLLPTVRIVAGVAAATTTLLMVITGVALCCWRHSK--------------ASASFSEQKNLMR-----------------------------IPGSSDGSSSRGPEEEETGSREDRGP---IVHTDHSDLVLEEEGTLETKDPTNGYYKVRGVSVSLSLGEAPGGGLFLPPPSPLGPPGTPTFYDFNPHLGMVPP--------------------CRLYRARAGYLTTPHPR--------------------AFTSYIKPTSFGPPDLAPGTPPFPYAAFPTPSHPR--LQTHV--------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W4T9-1", "uniprot_id": "Q9W4T9_DROME", "id": "Q9W4T9-1", "name": "", "aln": "MKRMRSSRLLVLPLILVLILTLLLQPIAVHAKSKKNKSSQSSHHGDSSSSSSSSSSSSGSSSAAASSANDESKPKGGDNGGQHFAMEPQDQTAVVGSRVTLPCRVMEKVGALQWTKDDFGLGQHRNLSGFERYSMVGSDEEGDFSLDIYPLMLDDDAKYQCQVGPGPQGEQGIRSRFAKLTVLVPPEAPKITQGDYLVTTEDREIELECVSQG-GKPAAEITWIDGLGNVLTKGIEYVKEPLADSRRITARSILKLAPKKEHHNTTFTCQAQNTADRTYRSAKLLLEVKYAPKVIVSVVGGALAGGKIPEGAEVILSCQADANPHELSYRWFINDELMTGDFTTKMIIHNVSRQYHDAIVKCEVVNAVGKSEQSKKLDISFGPVFRQRPVSVEADLGATVSMRCDVAGNPEPEIEWISENSDQVVGVAAELKLK-VSSETAGRYFCKAVVN--GFPEIGAEATLYVKRAPIITSHKVQFGGVGGRVKIDCLAFSIPKAEHILWSFEGKIINMSS-----ADPDIYIFEEHHLPEGVRAALIIRDSKATHFG-KYNCTVMNSYGGDSLVITLLREPGNIPVLLVVMGSMFCVAIILMIVMIIIVYRKRRSRKKPMPADVIPEASRGGDKLNELKSELRSKAYDVEYSEAGGDGLAINLTQSPMPDVQMKGATLGVPLAGPVKFDERFSGDFGGDRYNRQCHIKNLKNQQETAYKGSPQANGYAHYFEYALDYSPPGGEGAAVVVGSGGVGKLKNGGMNSATLPHSAAATVNGGGAGNGGGASLPRNQRHEIQQSQQSNGFLGQPLLQNGIDSRFSAIYGNPYLRTNSSLLPPLPPPSTANPAATPAPPPYHAARHGHAHHANGGLKHFVGGAVITTSPVGNVNINGGGGGGSTPSGGGGVGVGVAAGGSVSGSSSNLTASSNTLAATPLAGGGVGNSGQCAQSPSGQFILSNNGKGHTQKGPLATHV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . ***. : * . . ** :*:* ..::*... *** : * :****..:.** .*:*.*:.** : *. .*:..*.* *: *:*:*.*:**. : *:*** *:* *:******:: * : . . :* * *:* .:*:.*: *: ..: .* : : * : :... * *:* .....:*: *:*:. * * *.: : *.::*.* * :*. . ** :* : *** *:* .*** ... : * .:: : .. : *.*** ****.:::*. *:: :**::: :* .*..*:* .*: * *** *.: * .. **:. .. *:* *. * ** *.*:* *. *:* * *: .*::*: : . : * .:::*:.*: * .: ::**:: ::: .* .:. . *: :.* * .:: :.* :**:. * * . * *. . :*.: :* * ..: ::*:: : : *:. .:.: *. :* : *:: * . ** : * * : . .:* ::: : : . :*** : ::. * . *..:.: . . . ** .. : : *:* * : :: : *.* . * :...**: * . * . *: .* ", "identical_positions": 176, "similar_positions": 248, "identity": "18.22%" }, { "cls_id": "homologset.agr.RGD:1308457", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JK30-1", "uniprot_id": "ORC3_MOUSE", "id": "Q9JK30-1", "name": "Origin recognition complex subunit 3", "aln": "MHTGPRTMATSSVSKGCFVFKPDFKKRKVFVPIEDYFNNEELDSEDSKLRFETYSLLWQRMKSETEQLQEELNENLFDNLVDFLQKSHPEFQKNSRDWGSQMKFREIPTAALILGVNVTDHDVILRSLTETLQNNVTPYVVSLQAKDCPDVKHFLQKFTSQLMDCCVDRHSKEV-TSGKALKKTNYSMDSLCSWYSAVTQKADHKVTIKKRTASGHWRSPPVVLILKSMESFTSKVLQDFITISS--QHLHEFPLILIFGIATSPVIIHRLLPHSVSSLLCVELFQSLSCE----QHLTVVLDKLLLTPQFPFKLSKKALQVLTNIFLY-HDFSIQSFIKGIKLSLLEHFYSQPLSVLCCDLSEAKKRVNVFSVSQCENIRRLPSFRRYVENQPLGKQVALLTNETFLKEKTQSLLEDLHVYHINYFLVLRCLHNFTSSLPKYPLGRQIRELYCTCLEKKIWDSEEYKSALQLLRMLAKDELVSILQRCIEVLDSSTEKQLGNTTQKIKDFLTQFQNLDADSKEEEDACGSQPKGLQKTDLYHLQKSLLEMKELRR-TKKPTKFEMLRENVMNFIDNLVRDYLLPPESQPLHEVVYFSAANTLREHLNAAPRIALHTALNNPYYYLKNEEL---EGCIPNTAPDICIAYKLHLECSLLINLVDWAEAFATVVTAAEKMDANSTVSEEMSEVIHARFIRAVSELELLGFIKPTKQKT-DHVARLTWGGC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4R180-1", "uniprot_id": "ORC3_RAT", "id": "Q4R180-1", "name": "Origin recognition complex subunit 3", "aln": "-------MATSSVSKGCFVFKPDFKKRKISVPIEDYFNNEELDSEDSKLRFETYRLLWQRIKSETEQLQEGLNENLFDNLVDFLQKSHSEFQKNSGNWGSQMRLREIPTAALILGVNVTDHDVIFRSLTETLHNNVTPYVVSLQAKDCPDVKHFLQKLTSELIDCCVDRNSKEE-KNDKALRRTSYSMDSLSSWYSTVAQKTGPKMTSKKRATCSQWQSPPVVLILKNMESFSTKVLQDFIIISS--QHLHEFPLILIFGIATSPVIIHRLLPHSVSSLLCIELFQSLSCK----EHLTVVLDKLLLTPQFPFKLSKKALQVLTNIFLY-HDFSIQNFIKGLKLSLLEHFYSQPLSVLCCDLSEAKKRINVFSVNQCEKIRRLPSFRRYVENQPLEKQVALLTNETFLKEETQSLLEDLHVYHINYFLVLRCLHNFTSSLPKYPLGRQIRELYCTCLEKKIWDSEEYESALQLLRMLAKDELMGILEQCVKVLNSSTEKQLSNTAQKIKGFLTQFQNLD-DSKEEEDACGSQPKGLQKTDLYHLQKSLLEMKELRRTTKKPTKFEMLRENVINFIDNLVRDYLLPPEGQPLHEVVYFSAANTLREHLNAAPRIALHTALNNPYYYLKNEALKSEEGCIPSVAPDICIAYKLHLECSRLINLVDWSEAFATVVTAAEKMDTNSTVSEEMSEIIHARFIRAVSELELLGFIKPTKQKT-DHVARLTWGGC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UBD5-1", "uniprot_id": "ORC3_HUMAN", "id": "Q9UBD5-1", "name": "Origin recognition complex subunit 3", "aln": "-------MATSSMSKGCFVFKPNSKKRKISLPIEDYFNKGKNEPEDSKLRFETYQLIWQQMKSENERLQEELNKNLFDNLIEFLQKSHSGFQKNSRDLGGQIKLREIPTAALVLGVNVTDHDLTFGSLTEALQNNVTPYVVSLQAKDCPDMKHFLQKLISQLMDCCVDIKSKEEESVHVTQRKTHYSMDSLSSWYMTVTQKTDPKMLSKKRTTSSQWQSPPVVVILKDMESFATKVLQDFIIISS--QHLHEFPLILIFGIATSPIIIHRLLPHAVSSLLCIELFQSLSCK----EHLTTVLDKLLLTTQFPFKINEKVLQVLTNIFLY-HDFSVQNFIKGLQLSLLEHFYSQPLSVLCCNLPEAKRRINFLSNNQCENIRRLPSFRRYVEKQASEKQVALLTNERYLKEETQLLLENLHVYHMNYFLVLRCLHKFTSSLPKYPLGRQIRELYCTCLEKNIWDSEEYASVLQLLRMLAKDELMTILEKCFKVFKSYCENHLGSTAKRIEEFLAQFQSLD-ETKEEEDASGSQPKGLQKTDLYHLQKSLLEMKELRR-SKKQTKFEVLRENVVNFIDCLVREYLLPPETQPLHEVVYFSAAHALREHLNAAPRIALHTALNNPYYYLKNEALKSEEGCIPNIAPDICIAYKLHLECSRLINLVDWSEAFATVVTAAEKMDANSATSEEMNEIIHARFIRAVSELELLGFIKPTKQKT-DHVARLTWGGC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P54790-1", "uniprot_id": "ORC3_YEAST", "id": "P54790-1", "name": "Origin recognition complex subunit 3", "aln": "-------MSDLNQSKKMNVSEFADAQRSHYTVYPSLPQSNKNDK-----HIPFVKLLSGKESEVNVEKRWELYHQLHSHFHDQVDHIIDNIEADLKAEISDLLYSETTQKRRCFNTIFLLGSDSTTKIELKDESSRYNVLIELTPKESPNVRMMLRRSMYKLYSAADAEEHPTIKYEDINDEDGDFTEQNNDVSYDLSLVENFKRLFG---------KDLAMVFNFKDVDSINFNTLDNFIILLKSAFKYDHVKISLIFNINTNLSNIEKNLRQSTIRLLKRNYHKLDVSSNKGFKYGNQIFQSFLDTVDGKLNLSDRFVEFILSKMANNTNHNLQLLTKMLDYSLMSYFFQNAFSVFIDPVN-----VDFLNDDYLKILSRCPTFMFFVEG---------LIKQHAPADEILSLLTNKNRGLEEFFVEFLVRENPINGHAKFVARFLEEELNITNFN---------------LIELYHNLLIGKLDSYLDRWSACKEYKDRLHFEPIDTIFQELFTLD------------------------------------------NRSGLLTQSIFPSYKSNIEDNLLS------WEQVLPSLDKENYDTLSGDLDKIMAPVLGQLFKLYR-------EANMTINIYDFYIAFRETLPKEEILNFIRKDPSNTKLLELAETPDA-------FDKVALILFMQAIFAFENMGLIKFQSTKSYDLVEKCVWRGI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: . ** * : :*. . :. : : :: *: : .. . . : * .:*..:: : ::: :: : .:: * . :.. . . .: ... ::.* .*:.*::: :*:: :* ... . . :: :. * : :: :. .:*. :*.::*: :.*::** : . : ... : ***.* *. *.: * ::. ** : .: .. :: . :::.:* * : :::..: ::.: . : :..:* : * :. **:.:*:.:.:**: : ::.:. . : : * *:* :** * :: :: ** : : ::*: : .: .. .*: .** * :: * * :: *: *: .. .: * : : *. :: :: .** .: :* :.:. . :.: **. * * * : : *.. : ..*.: : : *. :. *: **:: * . ::*:: : :.:: **. *: :.:: *::*: :* :*:** . *: * * : .* * ", "identical_positions": 88, "similar_positions": 242, "identity": "12.09%" }, { "cls_id": "homologset.agr.RGD:1308458", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "F1M7P1-1", "uniprot_id": "F1M7P1_RAT", "id": "F1M7P1-1", "name": "DDB1- and CUL4-associated factor 13", "aln": "MKVKMLSRNPDNYVRETKLDIQRVPRNYDPTLHPFEVPREYVRALNATKLERVFAKPFLASLD-GHRDGVNCLAKHPKSLATVLSGACDGEVKIWNLTKRKCIRTIQAHEGFVRGICTRF-----------CGTSFFTVGDDKTVKQWKMDGPGCGE-----------EEEPLYTVLGKTVYTGIDHHWKDPAFATCGQQVDIWDEQRTSPVCSMNWGFDSISSVKFNPIETYLLGSCASDRNIVLYDMRQATPLKKVILDMRTNTICWNPMEAFNFTAANEDYNLYTFDMRALDTPVMVHLDHVSAVLDVDYSPTGKEFVSASFDKSIRIFPVDKSRSREVYHTRRMQHVICVKWTSDSKYILCGSDEMNIRLWKANASEKLGVLTSRERAANDYNQKLKEKFQYHPHVKRIARHRHLPKSIYSQIQEQRVMKEARRRKEMNRRKHSKPGS-VPVVSERKKHVVAVVK-----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PAC3-1", "uniprot_id": "DCA13_MOUSE", "id": "Q6PAC3-1", "name": "DDB1- and CUL4-associated factor 13", "aln": "MKVKMLSRNPDNYVRETKLDIQRVPRNYDPTLHPFEVPREYVRALNATKLERVFAKPFLASLD-GHRDGVNCLAKHPKSLASVLSGACDGEVKIWNLTKRKCIRTIQAHEGFVRGMCTRF-----------CGTSFFTVGDDKTVKQWKMDGPGYGE-----------EEEPLYTVLGKTVYTGIDHHWKDPVFATCGQQVDIWDEQRTSPVCSMNWGFDSISSVKFNPVETFLLGSCASDRNIVLYDMRQATPLKKVILEMRTNTICWNPMEAFNFTAANEDYNLYTFDMRALDTPVMVHMDHVSAVLDVDYSPTGKEFVSASFDKSIRIFPVDKSRSREVYHTKRMQHVMCVKWTSDSKYIMCGSDEMNIRLWKANASEKLGVLTSREKAANDYNQKLKEKFQYHPHVKRIARHRHLPKSIYSQIQEQRVMKEARRRKEMNRRKHSKPGS-VPIVSERKKHVVAVVK-----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NV06-1", "uniprot_id": "DCA13_HUMAN", "id": "Q9NV06-1", "name": "DDB1- and CUL4-associated factor 13", "aln": "MKVKMLSRNPDNYVRETKLDLQRVPRNYDPALHPFEVPREYIRALNATKLERVFAKPFLASLD-GHRDGVNCLAKHPEKLATVLSGACDGEVRIWNLTQRNCIRTIQAHEGFVRGICTRF-----------CGTSFFTVGDDKTVKQWKMDGPGYGD-----------EEEPLHTILGKTVYTGIDHHWKEAVFATCGQQVDIWDEQRTNPICSMTWGFDSISSVKFNPIETFLLGSCASDRNIVLYDMRQATPLKKVILDMRTNTICWNPMEAFIFTAANEDYNLYTFDMRALDTPVMVHMDHVSAVLDVDYSPTGKEFVSASFDKSIRIFPVDKSRSREVYHTKRMQHVICVKWTSDSKYIMCGSDEMNIRLWKANASEKLGVLTSREKAAKDYNQKLKEKFQHYPHIKRIARHRHLPKSIYSQIQEQRIMKEARRRKEVNRIKHSKPGS-VPLVSEKKKHVVAVVK-----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q803X4-1", "uniprot_id": "DCA13_DANRE", "id": "Q803X4-1", "name": "DDB1- and CUL4-associated factor 13", "aln": "MKVKVLCRNPDDYVRETTRDIQRVPRNYDPTLHPFEVPREYTRALNATKLERVFAKPFVASLD-GHRDVISCITKHAKSLSTVISGACDGEVKVWNLPKRECTRTVQAHEGFVRGICSRF-----------CGTSFFTVGDDKTIKQWNMEAPGYGV-----------REEPINTILGKAVFTGIDHHQREGTFVTCGQTVDIWDEQRSSPVLSFSWGVDSFSSVRYNPVEPDLLASCASDRSIVLYDTRESAPLRKVIMQLRSNTLCWNPMEAYYFTCANEDYNLYTYDIRNLDVPVTVHMDHVSAVLDVDYSPTGREFVSASFDKTIRIFPKDKGHSREVYHTKRMQHVICVKWSADSKFIMSGSDEMNIRLWKANASEKLGVLSTREKTAANYNKKLIQKFQHHPQVRRIARHRHLPRDVLKQKRELKEMKEARRRKEQNVRKHSKPGS-VPLLTEKEKHVVKVVE-----------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VUN7-1", "uniprot_id": "Q9VUN7_DROME", "id": "Q9VUN7-1", "name": "DDB1- and CUL4-associated factor 13", "aln": "MKVKMISRNPDNYVRETKLQQHKMPRNYDPSLHPLEGPREYVRALNATKLDRVFAKPFVCNLS-GHRDGVSCFGKHPKQLSTLATGAYDGEVRIWDLANRISSRNFVAHDGFVRGIAYTQ-----------NGGRIFTVGDDKTIKVWKAEAPEVGE-----------DEVPVNTILSKFGLHGISHNRRDNKFATCGEVCAIWDERHNDPLKTLKWGVDTLHTISYNPVETSILACCASDRSIILYDQREAQPLRKVVLTMKSNKLAWNPMEAFNFTVANEDCNLYTFDTRKLQTPLKVHFDHVSAVTDVDYSPTGKEFVSASYDKTIRIYNAHHSHSRDIYHTKRMQHVVCVAWSLDNRYVFSGSDEMNVRMWKANASEKLGVIRPRERVNFNYQEALKQKYAAHPQIKRIARHRQVPRHVLNAQKKMRTVKEKEQVKEANVRKHTKKSKKVPYVSEKKKHVLKEEV-----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P33750-1", "uniprot_id": "DCA13_YEAST", "id": "P33750-1", "name": "Protein SOF1", "aln": "MKIKTIKRSADDYVPVKSTQESQMPRNLNPELHPFERAREYTKALNATKLERMFAKPFVGQLGYGHRDGVYAIAKNYGSLNKLATGSADGVIKYWNMSTREEFVSFKAHYGLVTGLCVTQPRFHDKKPDLKSQNFMLSCSDDKTVKLWSINVDDYSNKNSSDNDSVTNEEGLIRTFDGESAFQGIDSHRENSTFATGGAKIHLWDVNRLKPVSDLSWGADNITSLKFNQNETDILASTGSDNSIVLYDLRTNSPTQKIVQTMRTNAICWNPMEAFNFVTANEDHNAYYYDMRNLSRSLNVFKDHVSAVMDVDFSPTGDEIVTGSYDKSIRIYKTNHGHSREIYHTKRMQHVFQVKYSMDSKYIISGSDDGNVRLWRSKAWERSNVKTTREKNKLEYDEKLKERFRHMPEIKRISRHRHVPQVIKKAQEIKNIELSSIKRREANERRTR---KDMPYISERKKQIVGTVHKYEDSGRDRKRRKEDDKRDTQEK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:* : *..*:** .. : ::*** :* ***:* .*** :*******:*:*****: .*. **** : .: *: .* .: :*: ** :: *::. * .. ** *:* *:. ::: .****:* *. : . * : *. .: **. : .: *.* * :** .: .*: :.** *.: :: :* *. :*.. .**..*:*** * * :*:: :::* :.******: *. **** * * :* * *. .: *. ****** ***:**** *:*:.*:**:***: .:.:**::***:*****. * :: *.::::.***: *:*:*:::* *: .* .**: :*:: * ::: *.::**:***::*: : . . . . : :* * : . :* ::*::*::: ", "identical_positions": 155, "similar_positions": 153, "identity": "31.5%" }, { "cls_id": "homologset.agr.RGD:1308460", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZI66-1", "uniprot_id": "D3ZI66_RAT", "id": "D3ZI66-1", "name": "", "aln": "-------------MAARRRPAAGVGAR--DALAVLALA------LCAPGVGGGALEWYSATVSIEYVDPQSNLTVWSVTESG-------------RFGDSSLREERQGLVGVPRAP--ADAEGCAPDTRFVAP--GALGNAPWVALVARGGCTFKDKVLAAARRNASAVVVYNQERYGNATEPMSHAGTGSIVVIMISYPKGREISDLVQKGIPVKMRIEIGTRHMQEFISG--QSVVFVAIAFITMMIISLAWLIFYYIQRFLYTGS-QFGSQNHRKETKKVIGQLPLHTVKHGEKGIDVDAENCAVCIENFKVKDVIRILPCKHIFHRICIDPWLLDHRTCPMCKLDVIKALGYWGDPEDAQDLPIPEAAP-----------------GSVSVGNLSVTVQDEERSE-SNLPSSSSSEFGP-HRPCLKEDAEEDTALLGAGRSDPQHGGSIC----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3U2C5-1", "uniprot_id": "RN149_MOUSE", "id": "Q3U2C5-1", "name": "E3 ubiquitin-protein ligase RNF149", "aln": "-------------MAARRRPAAGVGAR--DALAVLALA------LCTPGVGGGALEWYSAMVSIEYVDPQSNLTVWSVSESG-------------RFGESSLREERQGLVGVPRAP--APAEGCAPDTRFVAP--GALGNAPWVALVARGGCTFKDKVLAAARRNASAVVVYNLESNGNATEPMSHAGTGNIVVIMISYPKGREIFDLVQKGIPVKMRIEIGTRHMQEFISG--QSVVFVAIAFITMMIISLAWLIFYYIQRFLYTGS-QFGSQNHRKETKKVIGQLPLHTVKHGEKGIDVDAENCAVCIENFKVKDVIRILPCKHIFHRICIDPWLLDHRTCPMCKLDVIKALGYWGDPEDTQELPTPEAAP-----------------GRVSVGNLSVTSQDEERSE-SNLPSSSSSESGP-HRPCLKEDAGEDTALLGAGRSEPQHGGSIC----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NC42-1", "uniprot_id": "RN149_HUMAN", "id": "Q8NC42-1", "name": "E3 ubiquitin-protein ligase RNF149", "aln": "-------------MAWRRREAS-VGARGVLALALLALA------LCVPGARGRALEWFSAVVNIEYVDPQTNLTVWSVSESG-------------RFGDSSPKEGAHGLVGVPWAPG-GDLEGCAPDTRFFVPEPGGRGAAPWVALVARGGCTFKDKVLVAARRNASAVVLYNEERYGNITLPMSHAGTGNIVVIMISYPKGREILELVQKGIPVTMTIGVGTRHVQEFISG--QSVVFVAIAFITMMIISLAWLIFYYIQRFLYTGS-QIGSQSHRKETKKVIGQLLLHTVKHGEKGIDVDAENCAVCIENFKVKDIIRILPCKHIFHRICIDPWLLDHRTCPMCKLDVIKALGYWGEPGDVQEMPAPESPP-----------------GRDPAANLSLALPDDDGSDDSSPPSASPAESEPQCDPSFKGDAGENTALLEAGRSDSRHGGPIS----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q06003-1", "uniprot_id": "GOLI_DROME", "id": "Q06003-1", "name": "E3 ubiquitin-protein ligase goliath", "aln": "MYIRKTLLLACLVLLFGGLPPLTFPATTTTLVAAMSIANQDLERYFRPGNGTHSFSGMEDRIAVDVYN--YAFLNWSYVEHGNMLCNMEFAQEQARYGEGKVLNVTGRLIHITATDNFSDDYACTPYIRGTLGAPIPDKGETWIALVRRGRCTFEEKVKHVYQQNAAGVIIYNDKQVMQLEKMQIKGKTRNIAAVITYQNIGQDLSLTLDKGYNVTISIIEGRRGVRTISSLNRTSVLFVSISFIVLMIISLVWLIFYYIQRFRYMQAKDQQSRNLCSVTKKAIMKIPTKTGKFSDE-KDLDSDCCAICIEAYKPTDTIRILPCKHEFHKNCIDPWLIEHRTCPMCKLDVLKFYGYVFLGSEESILEYQPDPPQGLALVEARDESADLNRSRDFVVDFPRVFVLDSGCVVGAREMLFPCRIPERSQSSLSLRQARDWVSLMSNKLEEQQGLRSMRNDEMQQVIK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . * :* :::* ** ::. . : :: : : ** * * *:*:.. : *: :. : . .*:* * .*:*** ** ***::** . ::**:.*::** : : :. * .*..:: *::: ::** *.: * * * :: : * **:**:*:**.:*****.********** * : : *:. . ***.* :: :* *..:: *:*:: **:*** :* .* ******** **: ******::***********:* ** : . : .* . . ::. . :. . . ... ..:. .: . * :.: : ::* ", "identical_positions": 113, "similar_positions": 117, "identity": "24.35%" }, { "cls_id": "homologset.agr.RGD:1308461", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LQB5-1", "uniprot_id": "A0ABK0LQB5_RAT", "id": "A0ABK0LQB5-1", "name": "MTOR-associated protein MEAK7", "aln": "MGNAKSLSGQKMGSRFLPEEQAEVDKLFDALS--SSDGG--VATGTFSLEALKSHVKEALPPAMVARLYNGMWRVKPTDRAHGSCRSVSREQFTVFLSHLLKGSCEEKGLMVMKMISVAEG-PTKTRDVQKFTEDLVASVVHVLTHR--HELRGWTWRKSTVPHDSMQAMVAQLLSEMKFQGKCGAAILCPVIQTLACWSASVVTTQTSQGGSAVACACLPCSAIAVGYPRVLQLCRSHCVIRLPPLVSVSEILDGQKFLGPQCLDQVCDQAMIEEWVFHVPLVGVFLSVVIHRGLCLLASS-------FDLSTLVPECHVDGGRPSESILDVLSVIYLSSHLAVEHRQCWRLLFSTQLHGQSFSQLCSLITSQGPSLIVLEDRDGYVFGGFASCSWEVKPQFQGDNKCFLFSIAPRMATYTPTGYNNHFMYLNYGQQTMPNGLGMGGQHHYFGLWVAADFGKGHSKAKPACTTYSSPQLSAQEDFQFEKMEVWGLGNLSEKDQ----GTNKKSILDSNPDARSLLEISGRTRHSEGLREVPKDED", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K0P3-1", "uniprot_id": "MEAK7_MOUSE", "id": "Q8K0P3-1", "name": "MTOR-associated protein MEAK7", "aln": "MGNAKSLSGQKMASRFLPEEQAEVDKLFDVLS--SSEGG--VATGTFSLEAMKSHVKEALPPAMVTRLYNGMQRVKPTDRTLGSCRSVSREQFTAFLSQLLRGSCEEKGLMVMNMISDAEG-PTKTRDVQKFTEDLVASVAHVLTHR--HELRGWTCRKSEVPPDSMQAMVAQLLSEMKFQ-------------------------------------------------------------------------DGYKFQGPQCLDQVCDQAMIEEWVFHVPHVGMFLSVVVHRGLCLLGSS-------FDPSTLVPECLADQGGRFESILDVLSVIYLSSHLAPEHRQRWRLLFSTQLHGQSFSQLCSHITSQGPSLLVLEDRDGYVFGGFASCSWEVKPQFQGDNRCFLFSIAPRMATHLHTGYNNHFMYLNYGQQTMPNGLGMGGQHHYFGLWVAADFGKGHSKAKPACTTYNSPQLSAQEDFLFDKMEVWGLGNLLEEYE----GKNKKSVLDSNPEARSLLEISGRARHSEGLREVPRDED", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6P9B6-1", "uniprot_id": "MEAK7_HUMAN", "id": "Q6P9B6-1", "name": "MTOR-associated protein MEAK7", "aln": "MGNSRSRVGRSFCSQFLPEEQAEIDQLFDALS--SDKNSPNVSSKSFSLKALQNHVGEALPPEMVTRLYDGMRRVDLTGKAKGPSENVSQEQFTASMSHLLKGNSEEKSLMIMKMISATEG-PVKAREVQKFTEDLVGSVVHVLSHR--QELRGWTGKEAPGPNPRVQVLAAQLLSDMKLQ-------------------------------------------------------------------------DGKRLLGPQWLDYDCDRAVIEDWVFRVPHVAIFLSVVICKGFLILCSS-------LDLTTLVPERQVDQGRGFESILDVLSVMYINAQLPREQRHRWCLLFSSELHGHSFSQLCGHITHRGPCVAVLEDHDKHVFGGFASCSWEVKPQFQGDNRCFLFSICPSMAVYTHTGYNDHYMYLNHGQQTIPNGLGMGGQHNYFGLWVDVDFGKGHSRAKPTCTTYNSPQLSAQENFQFDKMEVWAVGDPSEEQL----AKGNKSILDADPEAQALLEISGHSRHSEGLREVPDDE-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LWV7-1", "uniprot_id": "MEAK7_DANRE", "id": "Q1LWV7-1", "name": "MTOR-associated protein MEAK7", "aln": "MGNGDSVVAQKRLARFRPDERPAVEGTFDRLHGARSSASAGKTSKGLSLDMLQLTMGKMASESMIKRVFQGLHSIDP-GVPLHPGDGVSREQLLIFLADVLRGTAEERAPLVLAMAEGAKATVTTTEQIRGFMEDLVYAAVQTLAHK--GHLRAWHPERMGDGAQGVKLLAEQLTSELKPS-----------------------------------------------------------------------------------DQNSCDIACLEDWLFRIPMMAMFLELLIGEGLGVVLPS-------RPPPTLLPPCQFAPWTDLRCVLSLPLLMFLSPLLPEGHSAPWRMLFSTKMHGESFTRLLGSCKSRGPTVLLVKDTKGYIFGGFSSQSWEVKPQFQGDSRCFLFSVFPYMRVFTCTGYNDHYMYLNQGQQTMPNGLGMGGQHGYFGLWLDYDFGHGHSRARPRCTTYGSPQLSADEDFKLDTLEVWGVGKLPEEQEE---DEKKKSILDADLEVQAMMEMTGKTLHSQGLREPEEDED", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VM22-1", "uniprot_id": "Q9VM22_DROME", "id": "Q9VM22-1", "name": "MTOR-associated protein MEAK7", "aln": "MGNASGK--RETDNLYNSEELRMLESAYKNAS----GGALEKLTQDRLVETWSQTIERSLAESTAQYLFTPTK-------PGQQCVNLQLKKFGEPYYIMERGTIDQKMQMLLGSMERSGNDTFNSKQLEQYIYSVIKSYVHLESTAKNSGIKEWHDLGFNTTERSAATFAKGLMRNLGKE-----------------------------------------------------------------------------------LEHTMPNDALERWLHVTPQFLQIWREVFSQLYCRHGGSKRNIIKEMEIPILPALCDAPQNSHYRPIIELPHVLYINAQLPREHRHKWRFLFSSKINGESFSTMLGKVLDKGPTLFFIEDEDQYIFGGYASETWSVKPQFGGDDSSLLYTLSPAMRCFSATTYNNHYQYLNLNQQTMPNGLGMGGQFDFWGLWIDCSFGDGQS-VESCTTYRDYVQLSKRKQFKIRNMEVWAVGDLPVKEEDEEGDGHKRSVLDGNLEDRAMLEIAGKKMHSDGLREPNMDD-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***. . :. : .:* :: :. . : :. . : . . :: . .:. ::: : :*. ::: ::: . : .:.::. : .:: : .: : :: * :. * :: . : :* *:. * . : :. . * . * . . ::.: ::::.. *. : * :***::::*.**: : . :** : .::* . ::***::* :*.***** **. .:*::: * * . * **:*: *** .***:*********. ::***: .**.*:* ... * . *** ::* : .:***.:*. : ::*:**.: : ::::*::*: **:**** *: ", "identical_positions": 85, "similar_positions": 151, "identity": "15.57%" }, { "cls_id": "homologset.agr.RGD:1308462", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2KA67-1", "uniprot_id": "A0A0G2KA67_RAT", "id": "A0A0G2KA67-1", "name": "", "aln": "MGGRGLHYPQFFRNLWRSCWSSTPPTFFPSETRKRRKGRTPVLKGTGMVTTVSTLIKKMDFTEAYSDTCSTVGLAAREGNVKILRKLLKKGRSVDVADNRGWMPIHEAAYHNAVECLQMLIHTDSSENYIKTKTFEGFCALHLAVSQGHWKVTQILLEAGADPNTTTLEETTPLFLAVESGQIDVLKLLLQHGANVNGSHSMCGWNSLHQASFQGNAEAIKLLLKQGADRECQDDFGITPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAAQEGHTKCVELLLSNGADPDLYCNEDNWQLPIHAAAQMGHRKTLDLLIPLTNRACDSGPDKVSPVYSAVFGGREECLETLLQNGYSPDAQMCLVFGFSSPLCMALQKDCEFSGVVNILLKYGAQLNELHLAYCLKYEKFSMFCCFLKKGCLVVPWNHTSEFVSYAVKAQTKYKAWLPHLLLAGFDPLILLCSSSWVDSVSDDILIFTLEFSNWKRLPPAVEKMLSVRANSSFALQQHMASVPSLTHLCRLEIRSSLKAEHLHSDIFIHQLPLPRSLQSYLLYEEVLRMNGILEPATNHDGEIREAT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WV72-1", "uniprot_id": "ASB3_MOUSE", "id": "Q9WV72-1", "name": "Ankyrin repeat and SOCS box protein 3", "aln": "----------------------------------------------------------MDFTEAYSDTCSTVGLAAREGNVKILRKLLKKGRSVDVADNRGWMPIHEAAYHNAVECLQMLIHTDSSENYIKAKTFEGFCALHLAVSQGHWKITQILLEAGADPNETTLEETTPLFLAVESGRIDVLKLLLQHGANVNGSHSMSGWNSLHQASFQGNAETIRLLLKQGADRECQDDFGITPLFVAAQYGKLESMSILISSGANVNCQALDKATPLFIAAQEGHTKCVELLLSSGADPDLYCNEDNWQLPIHAAAQMGHTETLDLLIPRTNRACDTGPDKVSPVYSAVFGGREECLEMLLQNGYSPDAQMCLVFGFSSPLCMAFQKDCDFSGIVNILLKYGAQLNELHLAYCLKYEKFSMFCSFLKKGSLMVPWNHTSEFISYAVKAQTKYKAWLPHLLLAGFDPLILLCSSSWVDSASDDILIFTLEFSNWKRLPSAVEKMLSVRANSSWALQQHLASVPSLTHLCRLEIRASLKAEHLHSDIFIHQLPLPRSLQNYLLYEEVLRMNEILEPAANQDGETSKAT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y575-1", "uniprot_id": "ASB3_HUMAN", "id": "Q9Y575-1", "name": "Ankyrin repeat and SOCS box protein 3", "aln": "----------------------------------------------------------MDFTEAYADTCSTVGLAAREGNVKVLRKLLKKGRSVDVADNRGWMPIHEAAYHNSVECLQMLINADSSENYIKMKTFEGFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHGANVNGSHSMCGWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAAQEGHTKCVELLLSSGADPDLYCNEDSWQLPIHAAAQMGHTKILDLLIPLTNRACDTGLNKVSPVYSAVFGGHEDCLEILLRNGYSPDAQACLVFGFSSPVCMAFQKDCEFFGIVNILLKYGAQINELHLAYCLKYEKFSIFRYFLRKGCSLGPWNHIYEFVNHAIKAQAKYKEWLPHLLVAGFDPLILLCN-SWIDSVSIDTLIFTLEFTNWKTLAPAVERMLSARASNAWILQQHIATVPSLTHLCRLEIRSSLKSERLRSDSYISQLPLPRSLHNYLLYEDVLRMYEVPELAAIQDG------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *******:****************:*****************************:********::******** ************.******:.*********** **************.*:****:***************.*********** *** *:***::**::**********************:**************************************.***********.************* : ****** ******:* :************:*:*** **:******** *********:***:****:* *:**********:***************:* **:**. : **** **:.:*:***:*** ******:**********. **:**.* * *******:*** *..***:***.**..:: ****:*:*************:***:*:*:** :* ********:.*****:**** : * *: :** ", "identical_positions": 423, "similar_positions": 66, "identity": "72.56%" }, { "cls_id": "homologset.agr.RGD:1308463", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VHZ7-1", "uniprot_id": "IMP4_MOUSE", "id": "Q8VHZ7-1", "name": "U3 small nucleolar ribonucleoprotein protein IMP4", "aln": "MLRREARLRREYLYRKAREEAQRSVQEKKERVKRALEENQLIPTELRREALALQGSLEFDD---AGGEGVTSHVDDEYR-WAGVEDPKVMITTSRDPSSRLKMFAKELKLVFPGAQRMNRGRHEVGALVRACKANGVTDLLVVHEHRGTPVGLIVSHLPFGPTAYFTLCNVVMRHDIPDLGTMSEAKPHLITHGFSSRLGKRVSDILRYLFPV-PKDDSHRVITFANQDDYISFRHHVYKKTDHRNVELTEVGPRFELKLYMIRLGTLEQEATADVEWRWHPYTNTARKRVFLSAE----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5PQR5-1", "uniprot_id": "IMP4_RAT", "id": "Q5PQR5-1", "name": "U3 small nucleolar ribonucleoprotein protein IMP4", "aln": "MLRREARLRREYLYRKAREEAQRSVQEKKERVKRALEENQLIPTELRREALALQGSLEFDD---AGGEGVTSHVDDEYR-WAGVEDPKVMITTSRDPSSRLKMFAKELKLVFPGAQRMNRGRHEVGALVRACKANGVTDLLVVHEHRGTPVGLIVSHLPFGPTAYFTLCNVVMRHDIPDLGTMSEAKPHLITHGFSSRLGKRVSDILRYLFPV-PKDDSHRVITFANQDDYISFRHHVYKKTDHRNVELTEVGPRFELKLYMIRLGTLEQEATADVEWRWHPYTNTARKRVFLSAE----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96G21-1", "uniprot_id": "IMP4_HUMAN", "id": "Q96G21-1", "name": "U3 small nucleolar ribonucleoprotein protein IMP4", "aln": "MLRREARLRREYLYRKAREEAQRSAQERKERLRRALEENRLIPTELRREALALQGSLEFDD---AGGEGVTSHVDDEYR-WAGVEDPKVMITTSRDPSSRLKMFAKELKLVFPGAQRMNRGRHEVGALVRACKANGVTDLLVVHEHRGTPVGLIVSHLPFGPTAYFTLCNVVMRHDIPDLGTMSEAKPHLITHGFSSRLGKRVSDILRYLFPV-PKDDSHRVITFANQDDYISFRHHVYKKTDHRNVELTEVGPRFELKLYMIRLGTLEQEATADVEWRWHPYTNTARKRVFLSTE----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VBY2-1", "uniprot_id": "Q9VBY2_DROME", "id": "Q9VBY2-1", "name": "Brix domain-containing protein", "aln": "MLRKQARQRREYLYNKALTERLKSKQKIQETVVKSINENKAIGSKNVKKSLTAYKSLKYAD---EGVDDRT--VNDEYH-YAGCEDPKIMLTTSHNPSSRLKMFMKELRLIIPNAQQMNRGNYQLTTLMHACRANNVTDFLIVHEHRGIPDSLVVCHLPYGPTAFFNISDVVMRHDIPDIGHMSEQKPHLIFNNFKTPIGLRTVKILKHLFPV-PKENSQRVMSFLNHNDSIIFRHHQYKYVN-KELELTEVGPRFSLKLYQIKLGTLENIKAADTEWINRPYMNTSQKRLIFSNDPGIINKDTEA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53941-1", "uniprot_id": "IMP4_YEAST", "id": "P53941-1", "name": "U3 small nucleolar ribonucleoprotein protein IMP4", "aln": "MLRRQARERREYLYRKAQELQDSQLQQKRQIIKQALAQGKPLPKELAEDE-SLQKDFRYDQSLKESEEADDLQVDDEYAATSGIMDPRIIVTTSRDPSTRLSQFAKEIKLLFPNAVRLNRGNYVMPNLVDACKKSGTTDLVVLHEHRGVPTSLTISHFPHGPTAQFSLHNVVMRHDIINAGNQSEVNPHLIFDNFTTALGKRVVCILKHLFNAGPKKDSERVITFANRGDFISVRQHVYVRTR-EGVEIAEVGPRFEMRLFELRLGTLEN-KDADVEWQLRRFIRTANKKDYL-------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***::** ******.** . *: :: : ::: :.: : .: .. : .:.: : . : *:*** :* **::::***::**:**. * **::*::*.* ::***.: : *: **: ...**::::***** * .* :.*:*.**** *.: :******* : * ** :**** ..*.: :* *. **::** . **.:*.**::* *:.* * .*:* * . . :*::******.::*: ::*****: **.** : : .*:.*: : ", "identical_positions": 108, "similar_positions": 104, "identity": "35.29%" }, { "cls_id": "homologset.agr.RGD:1308464", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZEK9-1", "uniprot_id": "D3ZEK9_RAT", "id": "D3ZEK9-1", "name": "", "aln": "MAFALLRPVGAHVLYPDVRLLSEDEENRSESDASDQSFGCCEGLEAARRGPGPGSGRRASGG--AGPVVVVRQRQAANARERDRTQSVNTAFTALRTLIPTEPVDRKLSKIETLRLASSYIAHLANVLLLGDAADDGQPCFRAAGGGKSAVPAAD--GRQPRSICTFCLSNQRKGGSRRDLGGSCLKVRGVAPLRGPRR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60756-1", "uniprot_id": "TCF15_MOUSE", "id": "Q60756-1", "name": "Transcription factor 15", "aln": "MAFALLRPVGAHVLYPDVRLLSEDEENRSESDASDQSFGCCEGLEAARRGPGPGSGRRASNG--AGPVVVVRQRQAANARERDRTQSVNTAFTALRTLIPTEPVDRKLSKIETLRLASSYIAHLANVLLLGDAADDGQPCFRAAGGGKSAVPAAD--GRQPRSICTFCLSNQRKGGSRRDLGGSCLKVRGVAPLRGPRR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q12870-1", "uniprot_id": "TCF15_HUMAN", "id": "Q12870-1", "name": "Transcription factor 15", "aln": "MAFALLRPVGAHVLYPDVRLLSEDEENRSESDASDQSFGCCEGPEAARRGPGPGGGRRAGGGGGAGPVVVVRQRQAANARERDRTQSVNTAFTALRTLIPTEPVDRKLSKIETVRLASSYIAHLANVLLLGDSADDGQPCFRAAGSAKGAVPAAADGGRQPRSICTFCLSNQRKGGGRRDLGGSCLKVRGVAPLRGPRR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q59E67-1", "uniprot_id": "Q59E67_DROME", "id": "Q59E67-1", "name": "BHLH domain-containing protein", "aln": "MAVSSSSSSFSNYLMAVFAQDSNSSGSASGSGAAADSEDSQIGQEANPGGQENQGNHRRRPP-----------RQKINARERYRTFNVNSAYEALRNLIPTEPMNRKLSKIEIIRLASSYITHLSSTLETG---TECQPCLLHKYESEGIT--------RRISICTFCLKTK---------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.: . :: * . . *:.. . * *.*: :* .. * ** * ..:* ** ***** ** .**:*: ***.******::******* :*******:**:..* * : ***: .:. . : *******..: ", "identical_positions": 62, "similar_positions": 40, "identity": "31.16%" }, { "cls_id": "homologset.agr.RGD:1308466", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LND5-1", "uniprot_id": "A0ABK0LND5_RAT", "id": "A0ABK0LND5-1", "name": "Cystinosin", "aln": "MRGCFAEALGWGWNSLSNQVKLSVRLHFCGMSSLKSGNMMKNWLLILTLFLLKFIERSESTVGLSAPPTVKLVNGSSTNVSITLGHPLNSTLVITFEITFSSKNLTIVELPDEVIVPRGEKNASFQVTSQNIGQVTVYLHGNHSNQTCPR---IQFLVIHSRIVSVINQVIGWIYFMAWSVSFYPQVIQNWRRKSVVGLSFDFLALNLTGFVAYSVFNIGLLWVPYIQEEFLLKYPNGVNPVDINDAFFSLHAVALTLIVILQCCLYERGN--------------QRVSRPSIGFLVLAWLFILVTMIVAAVGVTTWLQFLFCFSYIKLIITLIKYFPQAYMNFYYKSTKGWSIGGVLLDFTGGSFSLLQMFLQSYNND--QWTLIFGDPTKFGLGVFTIFFDIVFFIQHFYLYRK--KPGLQAAPTGFDSHPSQN-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P57757-1", "uniprot_id": "CTNS_MOUSE", "id": "P57757-1", "name": "Cystinosin", "aln": "--------------------------------------MRRNWLLILTLFLLMFIEKYESTVSLTAPPTVKLENGSSTNVDITLGHPLNSTLVITFEVTFRSKNLTIVELPDEVIVPRGEKNASFQVTSQNIGQVTVFLHGNHSNQTCPR---IRFLVIHSRIVSIINQVIGWIYFMAWSVSFYPQVIQNWRRKSVIGLSFDFLALNLTGFVAYSVFNIGLLWVPYIQEEFLLKYPNGVNPVDSNDAFFSLHAVALTLIVILQCCLYERGN--------------QRVSWPSIGFLVLAWLFVLVTMIVAAVGITTWLQFLFCFSYIKLIITLIKYFPQAYMNFYYKSTKGWSIGGVLLDFTGGSFSLLQMFLQSYNND--QWTLIFGDPTKFGLGVFTIFFDVVFFIQHFYLYRK--KPGYDQLN-----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60931-1", "uniprot_id": "CTNS_HUMAN", "id": "O60931-1", "name": "Cystinosin", "aln": "--------------------------------------MIRNWLTIFILFPLKLVEKCESSVSLTVPPVVKLENGSSTNVSLTLRPPLNATLVITFEITFRSKNITILELPDEVVVPPGVTNSSFQVTSQNVGQLTVYLHGNHSNQTGPR---IRFLVIRSSAISIINQVIGWIYFVAWSISFYPQVIMNWRRKSVIGLSFDFVALNLTGFVAYSVFNIGLLWVPYIKEQFLLKYPNGVNPVNSNDVFFSLHAVVLTLIIIVQCCLYERGG--------------QRVSWPAIGFLVLAWLFAFVTMIVAAVGVTTWLQFLFCFSYIKLAVTLVKYFPQAYMNFYYKSTEGWSIGNVLLDFTGGSFSLLQMFLQSYNND--QWTLIFGDPTKFGLGVFSIVFDVVFFIQHFCLYRK--RPGYDQLN-----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VCR7-1", "uniprot_id": "CTNS_DROME", "id": "Q9VCR7-1", "name": "Cystinosin", "aln": "---------------------------------MDFSTHRLTTLLLLLLATVALGNAQSSQLTVDSHDITVLLNSNETFLVFANG-LLDSDVEVALGT--DSEDHLLLDPATFVYPAGSTRNQSVVITGLKAGNVKVVADSDDANKEIVKDVFVRVTVAKSRALIYTSIIFGWVYFVAWSVSFYPQIWSNYRRKSVEGLNFDFLALNIVGFTLYSMFNCGLYFIEDLQNEYEVRYPLGVNPVMLNDVVFSLHAMFATCITILQCFFYQRAQ--------------QRVSFIAYGILAIFAVVVVVSAGLAGGSVIHWLDFLYYCSYVKLTITIIKYVPQALMNYRRKSTSGWSIGNILLDFTGGTLSMLQMILNAHNYD--DWVSIFGDPTKFGLGLFSVLFDVFFMLQHYVFYRHSRESSSSDLTTVTDVQNRTNESPPPSEVTTEKY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P17261-1", "uniprot_id": "ERS1_YEAST", "id": "P17261-1", "name": "Cystine transporter", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------MVSLDDILGIVYVTSWSISMYPPIITNWRHKSASAISMDFVMLNTAG---YSYLVISIFLQLYCWKMTGDESDLGRPKLTQFDFWYCLHGCLMNVVLLTQVVAGARIWRFPGKGHRKMNPWYLRILLASLAIFSLLTVQFMYSNYWYDWHNSRTLAYCNNLFLLKISMSLIKYIPQVTHNSTRKSMDCFPIQGVFLDVTGGIASLLQLIWQLSNDQGFSLDTFVTNFGKVGLSMVTLIFNFIFIMQWFVYRSRGHDLASEYPL-----------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . ::* :*. :**:*:** : *:*:**. .:.:**: ** .* ** : .: : . * : * :.**. . : : * * *: : .:: : : . : * : :*: ::::**.**. * ** . :.* .::**.*** *:**:: : * : . :. : *.**.:.::.*:..*::* : : . . ", "identical_positions": 50, "similar_positions": 81, "identity": "11.14%" }, { "cls_id": "homologset.agr.RGD:1308467", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZM64-1", "uniprot_id": "A0A8I5ZM64_RAT", "id": "A0A8I5ZM64-1", "name": "RCC1 and BTB domain-containing protein 1", "aln": "MVDVGKWPIFTLLSPQETGSIRKACVFGISASEAIYVTDSDEVFVFGLNYSNCLGTGDNQSTLVPKKLEALCGKRIKSLSYGSGPHVLLSTEDGVVYAWGHNGYSQLGNGTTNQGIAPIQVCTNLLVKQVVEVACGSHHSMALAADGELFAWGYNNCGQVGSGSTANQPTPRKVTNCLHTKKVVNIACGQTSSMAVLDSGEVYGWGYNGNGQLGLGNNGNQLTPVRVAALHGVCVNQIVCGYAHTLALTDEGLLYAWGANTYGQLGTGSKNNLLSPTQIMVEKERVIEIAACHSTHTSAAKTQGGHVYMWGQCRGQSVILPHLTHFSCTDDVFACFGTPAVSWRLLSVEHEDFLTVAESLKKEFDSPETADLKFRIDGKYIHVHKAVLKIRCEHFRSMFQSYWNEDMKEVIEIDQFSYPVYRAFLQYLYTDTVDLPPEDAIGLLDLATSYCENRLKRLCQHIIKRGITVENAFSLFSAAVRYDAEDLEEFCFKFCINHLTEVTQTAAFWQMDGPLLKEFIAKASKCGAFKN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6NXM2-1", "uniprot_id": "RCBT1_MOUSE", "id": "Q6NXM2-1", "name": "RCC1 and BTB domain-containing protein 1", "aln": "MVDVGKWPIFTLLSPQEAGSIRKACVFGTSANEAIYVTDNDEVFVFGLNYSNCLGTGDNQSTLVPKKLEALCGKKIKSLSYGSGPHVLLTTEDGVVYAWGHNGYSQLGNGTTNQGIAPVQVCTNLLIKQVIEVACGSHHSMALAADGELFAWGYNNCGQVGSGSTANQPTPRKVTNCLHTKRVVNIACGQTSSMAVLDSGEVYGWGYNGNGQLGLGNNGNQLTPVRVAALHGMCVNQIVCGYAHTLALTDEGLLYAWGANTYGQLGTGSKNNLLSPTQIMVEKERVIEIAACHSTHTSAAKTQGGHVYMWGQCRGQSVILPHLTHFCCTDDVFACFGTPAVSWRLLSVEHEDFLTVAESLKKEFDSPEIADLKFRIDGKYIHVHKAVLKIRCEHFRSMFQSYWNEDMKEVIEIDQFSYPVYRAFLQYLYTDTVDLPPEDAIGLLDLATSYCENRLKRLCQHIIKRGITVENAFSLFSAAVRYDAEDLEEFCFKFCINHLTEVTQTAAFWQMDGPLLKEFIAKASKCGAFKN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NDN9-1", "uniprot_id": "RCBT1_HUMAN", "id": "Q8NDN9-1", "name": "RCC1 and BTB domain-containing protein 1", "aln": "MVDVGKWPIFTLLSPQEIASIRKACVFGTSASEALYVTDNDEVFVFGLNYSNCLGTGDNQSTLVPKKLEGLCGKKIKSLSYGSGPHVLLSTEDGVVYAWGHNGYSQLGNGTTNQGIAPVQVCTNLLIKQVVEVACGSHHSMALAADGEVFAWGYNNCGQVGSGSTANQPTPRKVTNCLHIKRVVGIACGQTSSMAVLDNGEVYGWGYNGNGQLGLGNNGNQLTPVRVAALHSVCVNQIVCGYAHTLALTDEGLLYAWGANTYGQLGTGNKNNLLSPAHIMVEKERVVEIAACHSAHTSAAKTQGGHVYMWGQCRGQSVILPHLTHFSCTDDVFACFATPAVSWRLLSVEHEDFLTVAESLKKEFDSPETADLKFRIDGKYIHVHKAVLKIRCEHFRSMFQSYWNEDMKEVIEIDQFSYPVYRAFLQYLYTDTVDLPPEDAIGLLDLATSYCENRLKKLCQHIIKRGITVENAFSLFSAAVRYDAEDLEEFCFKFCINHLTEVTQTAAFWQMDGPLLKEFIAKASKCGAFKN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B8A4R1-1", "uniprot_id": "B8A4R1_DANRE", "id": "B8A4R1-1", "name": "", "aln": "MVDVSKWPLFTLLSAQELSSIRQACIFGASANEAIYITHDDEVYVLGLNCSNCLGTGDSQSTIAPKKLDCLSGKKLISLSYGSGPHVLLVTEDGELYAWGHNGYSQLGNGTTNQGVSPILVSTNLQGKRVTEVSCGSHHSLALTHEGEVFAWGYNNCGQVGSGSTANQPTPRKVSNCLQNKVIVNIACGQTSSMAVTDNGEVYGWGYNGNGQLGLGNNGNQLTPCRLIALQGFCVLQIASGYAHSLALTDEGLLYAWGANTYGQLGTGNKSNQLSPVQVMTEKERIVEIAACHSTHTSAAKTQSGQVYMWGQCRGQAIVLPHLTHFASTDDVFACFATPSVMWRMLSMEHDDFLTVAQSLKKEFDNPETSDLKFSIDGKYIHVHKAVLKIRCEHFRSMFQSHWNEDMKEVIEIDQFSYPVYRSFLEFLYTDSVDLPPEDAIGLLDLATSYCENRLKKLCQHIIKRGITVENAFSLLSAAIRYDAEDLEEFCFKFCVNHLTEVTQTAAFWQIDGNMLKEFICRASHCGAFKN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****.***:*****.** .***:**:** **.**:*:*..***:*:*** ********.***:.****: *.**:: ************ **** :*******************::*: *.*** *:* **:******:**: :**:*************************:***: * :*.*********** *.************************* *: **:..** **..****:***********************.*.* ***.::*.****::*******:********.*:**********:::*******..********.**:* **:**:**:******:*******.** :**** **************************:********************:**::****:************************:******************:***:***************:**************:** :*****.:**:******", "identical_positions": 427, "similar_positions": 81, "identity": "80.41%" }, { "cls_id": "homologset.agr.RGD:1308468", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "B1WC44-1", "uniprot_id": "B1WC44_RAT", "id": "B1WC44-1", "name": "60S ribosomal export protein NMD3", "aln": "--MEYMTESVD--------RSPGHILCCECGVPISPNP-ANICVACLRSKVDISQGVPKQVSISFCKQCQRYFQPPASWVQCALESRELLALCLKKIKAPLSKVRLVDAGFVWTEPHSKRLKVKLTIQKEVMNGAILQQVFVVDYVVQSQMCGDCHRVEAKDFWKAVIQVRQKTLHKKTFYYLEQLILKYGMHQNTLRIKEIHDGLDFYYSSKQHAQKMVEFLQGTVPCRYKSSQRLISQDIHSNTYNYKSTFSVEIVPICKDNVVCLSPKLAQSLGNMNQICICIRVTSAIHLIDPNTLQVADIDGNTFWSHPFNSLCHPKQLEEFIVIECSIVR--DLKRNAGAGVISKKHTLGEVWIQKTSEMDT-DKQYFCRTHLGHLLNPGDLVLGFDLANCNLNDEHVNKMKSDRVPDVVLIKKSYDRTKRQRRRNWKLKELARDREDMDT--------------DDERQYQDFLEDLEEDETIRKNVNIYRDS--TVPV-ESDTD---DEGAPRISLAEMLEDLRISQ--DATGEEGASMMS----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99L48-1", "uniprot_id": "NMD3_MOUSE", "id": "Q99L48-1", "name": "60S ribosomal export protein NMD3", "aln": "--MEYMAESIE--------HSPGHILCCECGVPISPNP-ANICVACLRSKVDISQGVPKQVSISFCKQCQRYFQPPASWVQCALESRELLALCLKKIKAPLSKVRLVDAGFVWTEPHSKRLKVKLTIQKEVMNGAILQQVFVVDYVVQSQMCGDCHRVEAKDFWKAVIQVRQKTLHKKTFYYLEQLILKYGMHQNTLRIKEIHDGLDFYYSSKQHAQKMVEFLQGIVPCRYKASQRLISQDIHSNTYNYKSTFSVEIVPICKDNVVCLSPKLAQSLGNMSQICICIRVTSAIHLIDPNTLQVADIDGNTFWSHPFNSLCHPKQLEEFIVIECSTVR--DLKRSAGAGVISKKHTLGEVWIQKTSEMNT-DKQYFCRTHLGHLLNPGDLVLGFDLANCNLNDEYVNKMNSDRVPDVVLIKKSYDRTKRQRRRNWKLKELARDRENMDT--------------DDERQYQDFLEDLEEDEAIRKHVNIYRDA--TIPV-ESDTD---DEGAPRISLAEMLEDLHISQ--DATGEEGASMMS----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96D46-1", "uniprot_id": "NMD3_HUMAN", "id": "Q96D46-1", "name": "60S ribosomal export protein NMD3", "aln": "--MEYMAESTD--------RSPGHILCCECGVPISPNP-ANICVACLRSKVDISQGIPKQVSISFCKQCQRYFQPPGTWIQCALESRELLALCLKKIKAPLSKVRLVDAGFVWTEPHSKRLKVKLTIQKEVMNGAILQQVFVVDYVVQSQMCGDCHRVEAKDFWKAVIQVRQKTLHKKTFYYLEQLILKYGMHQNTLRIKEIHDGLDFYYSSKQHAQKMVEFLQCTVPCRYKASQRLISQDIHSNTYNYKSTFSVEIVPICKDNVVCLSPKLAQSLGNMNQICVCIRVTSAIHLIDPNTLQVADIDGSTFWSHPFNSLCHPKQLEEFIVMECSIVQ--DIKRAAGAGMISKKHTLGEVWVQKTSEMNT-DKQYFCRTHLGHLLNPGDLVLGFDLANCNLNDEHVNKMNSDRVPDVVLIKKSYDRTKRQRRRNWKLKELARERENMDT--------------DDERQYQDFLEDLEEDEAIRKNVNIYRDS--AIPV-ESDTD---DEGAPRISLAEMLEDLHISQ--DATGEEGASMLT----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5BLF0-1", "uniprot_id": "NMD3_DANRE", "id": "Q5BLF0-1", "name": "60S ribosomal export protein NMD3", "aln": "--MEYMQAPPS--------SSHGNILCCTCGVPIPPNP-ANMCVSCLRTQVDISEGIPKQVTIHFCRQCERYLQPPGSWVQCALESRELLALCLKKLKASMSKVRLIDAGFLWTEPHSKRIKIKLTIQKEVMNGAILQQVFTVEFVVQGQMCEDCHRVEAKDFWKAVVQVRQKTVHKKTFYYLEQLILKHKLHQNTVRIKEIHEGIDFYYATKQHAQKMVDFLQCTVPCRSKASQRLISHDVHSNTYNYKSTFSVEIVPVCKDNVVCLSPRLAQSLGNMGQVCVCVRVTSSIHLIDPNTLQIAEVDGSTFWRHPFNSLCSPRQLEEFIIMDIDIIR--DQRLGAGAGLKSNKHTLAEVWVQKTSEMDS-SHQYHCRTFMGHLLNIGDLVLGFDFANANINDEFLNKMNPQHVPDVVLIKKSYDRMKRARKRVWKLKEMDREKDAADT--------------DDERQYTEFLEDLEEDEMLRKNINIFRDAS-KIPVEESDTD---DDGAPRISLAEMLEDLSLS---DATGGEGADMMTD---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O46050-1", "uniprot_id": "O46050_DROME", "id": "O46050-1", "name": "60S ribosomal export protein NMD3", "aln": "MDHEYVGVSPLGAADGKGAGSNAVILCCECGVAIQPNP-ANMCVTCLRNHVDITENIPKQAVLHFCRNCERYLQPPNEWIQAALESRELLAICLKKLKG-LKEVKLVDAGFIWTEQHSKRIKVKLTVHGEIIGGTMLQQVFVVEFTVQNQMCNDCHRTEAKDFWRCLVQVRQRAENKKTFYYLEQLILKHKAHENTLGIKPEHGGLDFFYANDNHARRMVDFLLTMVPGKVTTSKRLISHDIHSNNYNYKYNWSVEIAPVSKDSAVCLSKKLRHQLGNLSPLVLVNRVSSSIHLIDPLTAQIAELTSQVYFRAPFEAVCNPKQLVEYVVMDIDVIMEKDRKTYPGQGQVSFKHALCDIWVVRASELGINDNPIHTRSHLGHLLKVGDSVMGYNTGEANINDLEFDKLSSDEIPDVILVRKHYDRQTRLSQRVWKIKHLA--AEATDE--------------RSKYDYHEFLDDLEENEDIRGQVNIYRDTN-KTIPIEVQAA---GGDVPQITLEEMLEDMTLECADDEMGEEGGADDTEPQL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38861-1", "uniprot_id": "NMD3_YEAST", "id": "P38861-1", "name": "60S ribosomal export protein NMD3", "aln": "--MEFTPIDPHQH------QNAATLLCCNCGTPIDGSTGLVMCYDCIKLTVDITQGIPREANISFCRNCERFLQPPGQWIRAELESRELLAICLRRLKG-LTKVRLVDASFIWTEPHSRRIRIKLTVQGEAMTNTIIQQTFEVEYIVIAMQCPDCARSYTTNTWRATVQIRQKVPHKRTFLFLEQLILKHNAHVDTISISEAKDGLDFFYAQKNHAVKMIDFLNAVVPIKHKKSEELISQDTHTGASTYKFSYSVEIVPICKDDLVVLPKKLAKSMGNISQFVLCSKISNTVQFMDPTTLQTADLSPSVYWRAPFNALADVTQLVEFIVLDVDSTG-----------ISRGNRVLADITVARTSDLGVNDQVYYVRSHLGGICHAGDSVMGYFIANSNYNSDLFDGLNIDYVPDVVLVKKLYQRKSK-KSRHWKLKRMAKEHKDIDASLDYNSRAQKQEMERAEKDYELFLQELEEDAELRQSVNLYKNREANVPPEEHEMDEDEDEDAPQINIDELLDELDEMT--LEDGVENTPVESQQ--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: . . :*** **..* .. :* *:: ***::.:*::. : **::*:*::*** *::. ********:**:::*. :.:*:*:**.*:*** **:*:::***:: * : .:::**.* *:: * * ** * :.: *:. :*:**:. :*:** :*******: * :*: *. : *:**:*: .:** :*::** ** : . *:.***:* *:. .** .:****.*:.**. * *. :* :.:**:. . : :::.:::::** * * *:: ..:: **:::. ** *::::: . ::.* :: : ::*::. .: . *:.:* : : ** *:*: .:.* *. .: :. : :***:*::* *:* .: * **:*.: . * : :* **::***: :* :*:::: * : . ..*:*.: *:*::: * *. : ", "identical_positions": 151, "similar_positions": 191, "identity": "27.81%" }, { "cls_id": "homologset.agr.RGD:1308469", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D8M4-1", "uniprot_id": "RL7L_MOUSE", "id": "Q9D8M4-1", "name": "Large ribosomal subunit protein uL30-like 1", "aln": "---------MAEEGERKKIPLVPENLLKKRKAYQALKATQAKQALLAKRE-RKGKQFRFRRLESFVHDSWRQQRDKVRVQRLEVKPR------------------------------------------------ALEVPDKHPLAFVIRMER--IEGVSLLVKSTIMKLGLKKLFSGVFVKVTPQSVRMLRTVEPYVTWGFPNLKSVRELILKRGQAKINNK------TVPLTDNTVIEEHLGRFGVICLEDLIHEIAFPGKHFQEVSSFLCPFLLSVARHATRNRVGFRKEMGSPGYRGDR--------------INQLIRQLN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A1K2-1", "uniprot_id": "D4A1K2_RAT", "id": "D4A1K2-1", "name": "", "aln": "MSSSWSTGKMAEEGERKKIPLVPENLLKKRKAYQALKATQAKQALLAKRE-RKGKEFRFRRLESFVHDSWRQQRDKVRVRRLEVKPR------------------------------------------------ALEVPDKHSLAFVIRMER--IQGVSLLVKSTIMKLGLKKLFSGVFVKVTPQSMRMLRTVEPYVTWGFPNLKSVRELILKRGQAKINNK------TVPLTDNTVIEEHLGQFGVICLEDLIHEIAFPGKHFQQISSFLCPFHLSVARHATKNRVGFLKEMGSPGYRGDR--------------INQLIRQLN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6DKI1-1", "uniprot_id": "RL7L_HUMAN", "id": "Q6DKI1-1", "name": "Ribosomal protein uL30-like", "aln": "MISSCTTRKMAEQ-EQRKIPLVPENLLKKRKAYQALKATQAKQALLAKKEQKKGKGLRFKRLESFLHDSWRQKRDKVRLRRLEVKPH------------------------------------------------ALELPDKHSLAFVVRIER--IDGVSLLVQRTIARLRLKKIFSGVFVKVTPQNLKMLRIVEPYVTWGFPNLKSVRELILKRGQAKVKNK------TIPLTDNTVIEEHLGKFGVICLEDLIHEIAFPGKHFQEISWFLCPFHLSVARHATKNRVGFLKEMGTPGYRGER--------------INQLIRQLN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P40693-1", "uniprot_id": "RLP7_YEAST", "id": "P40693-1", "name": "Ribosome biogenesis protein RLP7", "aln": "--MSSTQDSKAQTLNSNPEILLRKRRNADRTRIERQELAKKKREEQIKKKRSNK--NKFVRAESIVAKTLATSREKERIKRVSILEDKKAKNETQHIASGKDFILKITEKANGAEENSVDLEETEEEEDDGLIREKTTYDGKPALLFIVRVRGPLAVNIPNKAFKILSLLRLVETNTGVFVKLTKNVYPLLKVIAPYVVIGKPSLSSIRSLIQKRGRIIYKGENEAEPHEIVLNDNNIVEEQLGDHGIICVEDIIHEIATMGESFSVCNFFLQPFKLNREVSGFGSLNRLRKIKQREAESRTRQFSNAATAPVIEVDIDSLLAKLN", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VKC1-1", "uniprot_id": "Q9VKC1_DROME", "id": "Q9VKC1-1", "name": "", "aln": "---MSDKYAVPNKLPGKTVSVLKHRK---RRILQDESVVTQKRNDRIKKRTATKNHHKFRRAESFVMGYLKAERTSKRIKQTILRTN-------------------VTEQSAKAAD-----------------------DSNPKLLFVMRHAG--KKIFDKTTADIFRTLRMGSRHNAVFMENTKENQLLLRVIEPFVVYGNPSLSSIRELVFKKGFARIDGK------KTAIQSNTMVEQQLGDKGVICLEDIIHEICTVGPNFAAVNEFLCAFTLSSPSNGWQKKVSVSYKRGGEYGDRG-------------TAINELIARCL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: . :: .. * : . . *: *:. . :* * **:: .* . *::: : .: * *::* . . : * : . ..**:: * : :*: : *:*. * *.*.*:*.*: *:* ..: : .*.::*::** *:**:**:****. * * . ** .* *. . . . *:.*: : ", "identical_positions": 48, "similar_positions": 72, "identity": "14.72%" }, { "cls_id": "homologset.agr.RGD:1308470", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5PPI3-1", "uniprot_id": "GSKIP_RAT", "id": "Q5PPI3-1", "name": "GSK3B-interacting protein", "aln": "METDCNPVDLSSMSGFEEGSELNGFEGTDMKDMQLEAEAVVNDVLFAVNNMFVSKSLPCADDVAYINVETKERNRYCLELTEAGLRVVGYAFDQVEDHLQ----------------TPYHETVYSLLDTLSPAYREAFGNALLQRLEALKRDGQS------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BGR8-1", "uniprot_id": "GSKIP_MOUSE", "id": "Q8BGR8-1", "name": "GSK3B-interacting protein", "aln": "METDYNPVELSSMSGFEEGSELNGFEGADMKDMQLEAEAVVNDVLFAVNHMFVSKSMPCADDVAYINVETKERNRYCLELTEAGLRVVGYAFDQVEDHLQ----------------TPYHETVYSLLDTLSPAYREAFGNALLQRLEALKRDGQS------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P0R6-1", "uniprot_id": "GSKIP_HUMAN", "id": "Q9P0R6-1", "name": "GSK3B-interacting protein", "aln": "METDCNPMELSSMSGFEEGSELNGFEGTDMKDMRLEAEAVVNDVLFAVNNMFVSKSLRCADDVAYINVETKERNRYCLELTEAGLKVVGYAFDQVDDHLQ----------------TPYHETVYSLLDTLSPAYREAFGNALLQRLEALKRDGQS------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZWI4-1", "uniprot_id": "GSKIP_DANRE", "id": "Q7ZWI4-1", "name": "GSK3-beta interaction protein", "aln": "MEVDCKPEDLSKCSYDERCVELG-----EVKDMRLEAEAVVNDVLFAVSDMHVSHNLSSGLDVAYINVETREGNRYCLELTEAGLKVVGHTFDKVNDGLS----------------SQYHETVYSLLDSLSPGYREAFGNALLQRLERLKQNGQ-------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V8F3-1", "uniprot_id": "GSKIP_DROME", "id": "Q9V8F3-1", "name": "Protein GSKIP homolog", "aln": "---------MALVQSDEN----------DFHALR-EAQRMVDSCQDFADHLIVAEFLPHCRGVAYINIRTLEQVIYCVQLSRAGYRIVSYEFDDVADEVAN--------------CDTVYESAHQLLAGISPLYGEKYG--FGREPLGKRKEKQS------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VNV2-1", "uniprot_id": "Q9VNV2_DROME", "id": "Q9VNV2-1", "name": "GSKIP domain-containing protein", "aln": "-----MGEPKATADPGEE----------QAFNCEDEANAIINDVKAHVAEICISSKLASDATQIYLNIRTIESATCCVQVSSRGFKIVSSQYDTIDEDSRISALLRNGQEQGDDEEEEIFETPYALLDKISPRYVESFGNQLCQQLRALQQMRTEFNEEDEEEEEEAEEEEKK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . *. : . **: :::. . .: :: : *:*:.* * *:::: * ::*. :* : : .*: : ** :** * * :* : :. :: ", "identical_positions": 19, "similar_positions": 39, "identity": "10.98%" }, { "cls_id": "homologset.agr.RGD:1308471", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GKB1-1", "uniprot_id": "A0A8I6GKB1_RAT", "id": "A0A8I6GKB1-1", "name": "Molybdenum cofactor biosynthesis protein 1", "aln": "------------MAARPASRMLRQLLRSNVRSCS--------SGAPMTQPRPGEPSRPTREGLSMRLQFLQEHAAPFSAFLTDSFGRQHSYLRISLTEKCNLRCRYCMPEEGVSLTPKADLLTTEEILTLARLFVKEGVDKIRLTGGEPLIRPDVVDIVARLHQLEGLRTIGVTTNGINLARLLPSLQQAGLSAVNVSLDTLVPAKFEFIVRRKGFHKVMEGIHKAIELGYKPVKVNCVVMRGLNEDELLDFVALTEGLPLDVRFIEYMPFDGNKWNFKKMVSYKEMLDAIRQRWPGLEKLPEEDSSTAKAFKIPGFQGQISFITSMSEHFCGTCNRLRITADGNLKVCLFGNSEVSLRDHLR-AGASEEELLRIIGVAVGRKKRQHAGMFNIAQMKNRPMILIG-----VLLMLQD-------------------SPPASWSTLSWDPLHVR----------------------------NPGAKQCLSDQMATLWKRHSVPMALPLSQQCLGSGSPQRHYSSYPDPD---------THPKCLSTGS---------------------RAPDVPSGPGPTSDQLTHVDSAGRATMVDVGGKPETERVAVASAMVLLGPKAFKLVQQNQLKKGDALVVAQLAGVQAAKLTSQLIPLCHHVALSHVQVHLELDSTRHAVLIQVSCRARGPTGVEMEALTSAAMAALTVYDMCKAVSRDIVVTEVKLISKTGGQRGDFHRT-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5RKZ7-1", "uniprot_id": "MOCS1_MOUSE", "id": "Q5RKZ7-1", "name": "Molybdenum cofactor biosynthesis protein 1", "aln": "------------MAARPAFGIVRQLLRSNARGCS--------SGAPVTQPRPGEPSRPTREGLSLRLQFLQEHAAPFSAFLTDSFGRQHSYLRISLTEKCNLRCQYCMPEEGVPLTPKADLLTTEEILTLARLFVKEGVDKIRLTGGEPLIRPDVVDIVARLHGLEGLRTIGLTTNGINLARLLPRLQQAGLNAVNISLDTLVPAKFEFIVRRKGFHKVMEGIHKAIELGYKPVKVNCVVMRGLNEDELLDFVALTEGLPLDVRFIEYMPFDGNKWNFKKMVSYKEMLDTIRQRWPGLEKLPEEDSSTAKAFKIPGFQGQISFITSMSEHFCGTCNRLRITADGNLKVCLFGNSEVSLRDHLR-AGASEEELLRIIGAAVGRKKRQHAGMFNIAQMKNRPMILIG-----VLLMLQD-------------------SPPARWSNFSWDPLRVR----------------------------NPSARQCLSDQMASLWKRHCIPKALPLSQQCLGSGSPQRHYSSYPDPD---------THSKCLSTGS---------------------QAPDAPSGPGPTSNQLTHVDSAGRASMVDVGGKPETERVAVASAMVLLGPVAFKLVQQNQLKKGDALVVAQLAGVQAAKLTSQLIPLCHHVALSHVQVHLELDSTRHAVLIQASCRARGPTGVEMEALTSAAMAALTVYDMCKAVSRDIVVTEVKLISKTGGQRGDFHRA-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NZB8-1", "uniprot_id": "MOCS1_HUMAN", "id": "Q9NZB8-1", "name": "Molybdenum cofactor biosynthesis protein 1", "aln": "------------MAARPLSRMLRRLLRSSARSCS--------SGAPVTQPCPGESARAASEEVSRRRQFLREHAAPFSAFLTDSFGRQHSYLRISLTEKCNLRCQYCMPEEGVPLTPKANLLTTEEILTLARLFVKEGIDKIRLTGGEPLIRPDVVDIVAQLQRLEGLRTIGVTTNGINLARLLPQLQKAGLSAINISLDTLVPAKFEFIVRRKGFHKVMEGIHKAIELGYNPVKVNCVVMRGLNEDELLDFAALTEGLPLDVRFIEYMPFDGNKWNFKKMVSYKEMLDTVRQQWPELEKVPEEESSTAKAFKIPGFQGQISFITSMSEHFCGTCNRLRITADGNLKVCLFGNSEVSLRDHLR-AGASEQELLRIIGAAVGRKKRQHAGMFSISQMKNRPMILIE-----LFLMFPN-------------------SPPANPSIFSWDPLHVQ----------------------------GLRPRMSFSSQVATLWKGCRVPQTPPLAQQRLGSGSFQRHYTSRADSD---------ANSKCLSPGS---------------------WASAAPSGPQLTSEQLTHVDSEGRAAMVDVGRKPDTERVAVASAVVLLGPVAFKLVQQNQLKKGDALVVAQLAGVQAAKVTSQLIPLCHHVALSHIQVQLELDSTRHAVKIQASCRARGPTGVEMEALTSAAVAALTLYDMCKAVSRDIVLEEIKLISKTGGQRGDFHRA-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AJ79-1", "uniprot_id": "A0A8M3AJ79_DANRE", "id": "A0A8M3AJ79-1", "name": "Molybdenum cofactor biosynthesis protein 1", "aln": "MALNCNTFSRIIFGAHTAAEACVKFCRPVQQACGRYQMCRWYSGVTHEENRLEEVREPVVPGGHRR---VLKDVLPFSQFLTDSFGRRHNYLRISLTEKCNLRCQYCMPQDGVKLTPRSQLLTTHELLTVARLFVQEGVNKIRITGGEPLIRPDILHIIAELRKLEGLKTIAVTTNGMNLAKILPDLKKAGVDLLNISLDTLVPAKFEFITRRKGFHKVMEGIERAIEMGYNPVKVNCVVMRGLNEDELVDFVSLTERKPLDVRFIEYMPFNGNRWNFKMMVSYQEMLDCIKQKWPNLQPLPGEETDTAKAFQIPGFQGQMGFITSMSDHFCGSCNRLRITADGNLKVCLFGNAEVSLRDFLR-SGATEKELLHIIGAAVGRKKKQHAGMLNISKMKNRPMILIGRDCTWLLPMSPFRDNQRQTLPLIHRMDLAAISTTQSLGKCNHRPFHVIGYQDYKSTFVTDALYSFYSLTRFTNRKQNRKALEALCNDRISKSYRVTVSASKQNKSRMLLQHILQKHSRPPVPQSKIFALIPFLSTSRALLKDSALQFARHCHHKTPECGFHLKIRHKDLKSSLDGTSNQLTHTDAQGKASMVNVGAKAVTRRTATACGKVILGPKAFNLVCANQVAKGDALAVAQLAGIMGAKQTSNLIPLCHPLPLDHASVTIELLEEEHAAVIKATCQTTGRTGVEMEALTAVSIASLTLYDMCKSVSHDIIITDVKLLSKTGGQRGDYHL------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IQF1-1", "uniprot_id": "MOCS1_DROME", "id": "Q8IQF1-1", "name": "Molybdenum cofactor biosynthesis protein 1", "aln": "----------MRLLARHAIRLLGQENSAGEVASLS-------RGAIRLKATTGYLNLATASVQPLE---PEKQVLRKNSPLTDSFGRHHTYLRISLTERCNLRCDYCMPAEGVPLQPKNKLLTTEEILRLARIFVEQGVRKIRLTGGEPTVRRDIVEIVAQMKALPELEQIGITTNGLVLTRLLLPLQRAGLDNLNISLDTLKRDRFEKITRRKGWERVIAGIDLAVQLGYRP-KVNCVLMRDFNEDEICDFVEFTRNRPVDVRFIEYMPFSGNKWHTERLISYKDTLQIIRQRWPDFKALPNGPNDTSKAYAVPGFKGQVGFITSMTEHFCGTCNRLRLTADGNIKVCLFGNKEFSLRDAMRDESVSEEQLVDLIGAAVQRKKKQHA-------------------------------------------------------------------------------------------------------------------DAAPRLHHHLHPYSYHHAYHT----------------SRLQLQAR--------------------------------NYSQLTHVDGQGKAQMVDVGAKPSTTRLARAEATVQVGEKLTQLIADNQVAKGDVLTVAQIAGIMGAKRTAELIPLCHNISLSSVKVQATLLKTEQSVRLEATVRCSGQTGVEMEALTAVSVAALTVYDMCKAVSHDICITNVRLLSKSGGKR-DFQREEPQNGIVTEVE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *: : . .. *. : .. . :.. . *******:*.********:***** **** :** * *: .****.*:* :**:**::*: ***:***** :* *::.*:*.:: * *. *.:****: *:::* *::**:. :*:***** :** *.****:.:*: **. *:::**.* *****:**.:****: **. :*. *:**********.**:*: : ::**:: *: ::*:** :: :* ..*:**: :***:**:.*****::****:*****:*****:******* *.**** :* ..:*::*: :**.** ***:*** : : * :: . .: . .****.*. *:* **:** *. * * * * . * :* :*: **: ***.*.***:**: .** *::****** :.*. .* * . .::. ::.: : * *********:.::*:**:*****:**:** : :::*:**:**:* *:: ", "identical_positions": 245, "similar_positions": 165, "identity": "32.67%" }, { "cls_id": "homologset.agr.RGD:1308472", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A1B0GWY0-1", "uniprot_id": "A0A1B0GWY0_RAT", "id": "A0A1B0GWY0-1", "name": "", "aln": "MSLFKARDWWSTVLGE-KEEFDQGCLCLADVDNSRNGQVLHGDQKRASDNQDRSCWWFLSHHVSAANWTQHFLCKSNKIIVGSFMGYLRIFNPHPVKTGGGPQAEDLLLEVHLRDPVLQVEVGKFVS---GSEMLHLAVLHSRKLCVYSVSGTLGNVEHGNQYQIKLMYEHHLQRTACNMTYGPFGAVKGRDLICIQSMDGMLMVFEQESYAFGRFLPG-SLLPGPLAYSPRTDSFITVSSCRQVESYKYQVLAFATDADKKQEMEQQKLGSGKRLVVDWTLNIGEQALDICIIPLNQSASSVFVLGERNFFCLKDNGQIRFMKKLDCSPSCFLPYCS----VSEGTINTLVGNHNHMLHVYQDVTLKWATQLP---HVPVAVRVGCLHDLKGVIVTLSDDGHLQCSYLGTDPSLFQAPKVESRELNYDELDVELKELQKIIKDVK-SQGVWPLTEQEDD-----LKVSAAVSSALDSVSQATNVETGADSVPSITVKITLQNQVVLQKVKLSVYVQPPLQLTCDQFTFDFVAPDMTSIVTFSVYLKKTYTPSELEGNAVVSYSRAT-----GIPRVIQCKFRLPLNLICLPGQPSKTASHKLTIDTNKSPVS--LLGLFPDFANPSDDDQMNVMGFRLLGGSR----VTLLASRTSQRYRIQSERFEDLWLITNELILRLQDHFEKQGTKDFACSFSG---------------CVPLQEYFELIDHHFELRINGEKLEELLSERAVQFRAIQRRLLTRFRDKTPAPLQHLDTLLDGTYKQVIALADAVQENQDRLLQSFAGLKSATHLLILLIRLWQRLSADQTAILEAAFLPLQEDTQELGWEETVDAAVAHLLKT---CLSKSSKEQALNLSS-QLSVPKDTSRLKKHITLLCDRLAKGGRLCVSTDAAAPQAMVMPGGCTPIPESDLE---ERSLD-DATELFTN-----------------HKHLIAEPPVPE----------------VSALQGVLE------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q811G0-1", "uniprot_id": "PTHB1_MOUSE", "id": "Q811G0-1", "name": "Protein PTHB1", "aln": "MSLFKARDWWSTVLGE-KEEFDQGCLCLADVDNSGNG--------------------------------------HDKIIVGSFMGYLRIFSPHSVKAGGGPQAEDLLLEVHLRDPVLQVEVGKFVS---GTEMLHLAVLHSRKLCVYSVSGTLGNVEHGNQYQIKLMYEHHLQRTACNMTYGPFGGVKGRDLICIQSLDGMLMVFEQESYAFGRFLPG-FLLPGPLAYSPRTDSFITVSSCRQVESYKYQVLAFATDADKKQEMEQQKLGSGKRLVVDWTLNIGEQALDICIFPLNQSASSVFVLGERNFFCLKDNGQIRFMKKLGYNPSCFLPYCS----VSEGTINTLIGNHNHMLHIYQDVTLKWATQLP---HVPVAVRVGCFHDLKGVIVTLSDDGHLQCSYLGTDPSLFQAPKVESRELNYDELDVELKELQKIIKDVK-LQGVWPLTEQEDD-----LKVSASVSSTLDSVSQATNVEPGADSVPSITVKITLQNRVVLQKVKLSIYVQPPLQLTCDQFTFDFTVPDMTSSVAFSVYLKRNYTPSELEGNAVVSYSRPTDRNPDGIPRVVQCKFRLPLKLICLPGQPSKTASHKLTIDTNKSPVS--LLGLFPDFANPSDDDQVNVMGFRLLGGAR----VTLLASRTSQRYRIQSEQFEDLWLITNELILRLQEHFEKQGTKDFSCSFSG---------------CVPLQEYFELIDHHFELRINGKKLEELLSERAVQFRAIQRRLLTRFRDKTPAPLQHLDTLLDGTYKQVIALADAIEENQDRLLQSFSGLKSATHLLILLIRLWQRLSADQTAILEAAFLPLQEDTQELGWEETVDAAIAYLLKT---CLSKSSKEQALNLSS-QLNIPKDTSRLKKHITLLCDRLAKGGRLCVSTDAAAPQAMVVPGGCTPIPESDLE---ERSLD-DSTELFTN-----------------HKHLMTEPPMPE----------------VSARQGVLE------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3SYG4-1", "uniprot_id": "PTHB1_HUMAN", "id": "Q3SYG4-1", "name": "Protein PTHB1", "aln": "MSLFKARDWWSTILGD-KEEFDQGCLCLANVDNSGNG--------------------------------------QDKIIVGSFMGYLRIFSPHPAKTGDGAQAEDLLLEVDLRDPVLQVEVGKFVS---GTEMLHLAVLHSRKLCVYSVSGTLGNVEHGNQCQMKLMYEHNLQRTACNMTYGSFGGVKGRDLICIQSMDGMLMVFEQESYAFGRFLPG-FLLPGPLAYSSRTDSFLTVSSCQQVESYKYQVLAFATDADKRQETEQQKLGSGKRLVVDWTLNIGEQALDICIVSFNQSASSVFVLGERNFFCLKDNGQIRFMKKLDWSPSCFLPYCS----VSEGTINTLIGNHNNMLHIYQDVTLKWATQLP---HIPVAVRVGCLHDLKGVIVTLSDDGHLQCSYLGTDPSLFQAPNVQSRELNYDELDVEMKELQKIIKDVNKSQGVWPMTEREDD-----LNVSVVVSPNFDSVSQATDVEVGTDLVPSVTVKVTLQNRVILQKAKLSVYVQPPLELTCDQFTFEFMTPDLTRTVSFSVYLKRSYTPSELEGNAVVSYSRPTDRNPDGIPRVIQCKFRLPLKLICLPGQPSKTASHKITIDTNKSPVS--LLSLFPGFASQSDDDQVNVMGFHFLGGAR----ITVLASKTSQRYRIQSEQFEDLWLITNELILRLQEYFEKQGVKDFACSFSG---------------SIPLQEYFELIDHHFELRINGEKLEELLSERAVQFRAIQRRLLARFKDKTPAPLQHLDTLLDGTYKQVIALADAVEENQGNLFQSFTRLKSATHLVILLIALWQKLSADQVAILEAAFLPLQEDTQELGWEETVDAAISHLLKT---CLSKSSKEQALNLNS-QLNIPKDTSQLKKHITLLCDRLSKGGRLCLSTDAAAPQTMVMPGGCTTIPESDLE---ERSVEQDSTELFTN-----------------HRHLTAETPRPE----------------VSPLQGVSE------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AT49-1", "uniprot_id": "A0A8M3AT49_DANRE", "id": "A0A8M3AT49-1", "name": "", "aln": "MSLFKARDWWASVLGE-GEEFDQGCLCVGDVDNSGTG--------------------------------------YDKIIVGSFMGMLRIFSPHPAKPDELTEADTQLLEVQMPDPIIQVELGKFVS---CSESLHLAVLHPRKLSVYAVSGTAGNVEHGDQYQLRLVYEHNLQRTACNMTYGPFGGVTGHHFICIQSMDGMLMFFEQESYAFGRFLPG-FLLPGPLSYCIRTDSFITVSSTRQVECYRYETLAVATDADTKQDSNQQSKSSGKRLTADWTLVLGEEALDICVPNTSPAMSSIFVLGERNLFCLKDNGQIRFMKKLEFNPSCFLPYAS----VSEGSTNVLMCNHNNMLLVYQDVTLKWAAQLS---CVPVAVRVANFLELKGLVVTLSSDGHLQCSYMGTDPSFFTAPKVDAREVNYDEIDAEMKMLQRVIREATKTQDILPRAETEEE-----LRLTAVVSSSLDEVSCAIIPEMNGMPVPSVTVKVKIKSRAVVQNPKMTVCVQPPLAVTQDQFVLDSMGSGSELVVSFSAFLNGLYPPADMSGDIAVSYSSATELNPSGIPRVSQCKFSLPLRLVCYPSSAIKNAKYKITVDTNKPPVN--LNEVFPDFSEKSDNNDSSALGFQLITGSK----VIVLASKTSQRYRIQSESFEDIWLVAKELVQRFDQHFASLGVKDFRNSFTG---------------PIPLPEYFETVDHHFELRVNAQKYQDLLSERAVQFRAIQRRLLTRFKDKTPGPLQNLDTLMEGTYRQVLALADAAEDNRERLIQAFARLRSATHLLILLLSLWQGLNSEQTTILEATLLPLLQDTPQLGWEESVDAAVSHLLKT---CLSRSPKDQAISLSTGPLTIPKDTSRLKKHIMLLCDRLGKGGRLSLSSEANVPTAVMMPAACETIPEPIIEQDEEAPLQQDAAKYIKKKQSSKRVKSKSDSSKESSKEKKEKDPGKESTKETKKDSGKEKEAKVSTKESRRESTKEPKKESTKEPSKESSKDKELPREKEPSKEKTKVSRKSSVKAKEKKSEAGDG", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B7YZM8-1", "uniprot_id": "B7YZM8_DROME", "id": "B7YZM8-1", "name": "", "aln": "MSLFNVCSWWSAQCSDPGEEYDVASLLCARFGLETQE--------------------------------------KDYIIVGSQTGQLSIYYPHNR----GYDATDLLLETQMEAPIIGLYAGKFSGNVRNENANQLGVLLPNAIVIYNVVAIGGLAEHGAQLRLQVQAEHKFQRVSFGLCQGHFGQVKGREFFCVVHLDGTLTFFEQDGISYECRFPGHRALPAPVAYCERTDSFFRFSATWDLQCFSYQDLSHSLVTKSSYQP-------------TWSQGVGEGIVDMRVVQVRENCSYIMILGERNFISLDDNGKFNFMLKLDYAPKCFTSFVVGYYWEPGARLISAIISDSSKLHLYEEANIIWAAQWPNQSPAPVAIQRSNVQNLAGGIVTLGARGQLEVGYLGAEPFQFQVQPLNVEELSFAQAHKELQKLEDEIKEAVDVRDMDALNQQAADQVRLSFTIEQEANDDLDTLLLDVPADVAVKELPSAKGLLRCKIKAELAELQLVFQTPNGVRCSQDTLSFVNVSAGTSKEFKLDFYIAELLHIHSTKVEVVASFLSTR-----GIPRVIQQSANLPLSMFYRICQPQKAAGIKLTYSITSRHVSPKLATFFGEFLEEKSDTHALGLQLLCPGLEKQSEVITVVAAKNSNRFRIQSDYVETFAMILERIVERTLQLDSSAGLIKMDKKKPKRGVLNRCVERLMAAPFLPAQPILHRVDVHHETQQSIRKQTVQLEELWQQFKTLQRQLQE---QSESEPKEALTMQIESNYDQLILEGDKLVEIRRDERKQRCDLNCAVALAKWIIHALN-LEERVVNVVSSVLSVPIEDWTELSWEESMAPGIDMLHHFGPLTRSKSSSTHGLLDANAGNRDSFDYSRFRRHFATLFDRIVRLASSPVAVNPEKGKEEPSTEEKLPPTQQVDEIGNMQRMLGEKGLPLAP-----------------PKRRANMSSSLEA---------------VEDDEEYDEEDLREDVGYRKEYGATDQKNPNHKKRSEWVNEDFELPTTEELFSDLGIWW----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****:. .**:: .: **:* ..* . .. . : ***** * * *: ** :* ***..: *:: : *** . : :*.** .. : :* * . * .*** * :::: **::**.: .: * ** *.*:.::*: :** * .***:. :: :** **.*::*. *****: .*: :::.: *: *: : :.. : *: :** :*: : * :::*****::.*.***::.** ** *.** .: . . : ... * :*::..: **:* . ***:: . . :* * :***. *:*: .*:*::* * . :: .*:.: : . *:: *: *::. :.: . : : : : .. :* : : :** . : : :. : : :: . . : : * : : .. . :. :: . . : ..*: . ***** * . *** :. .. * * *:* . .. *. * .* * . ..: . : : : : ::*::.*:*:****: .* : :: :.:: * : . * .: . . :* :. :* *.* : . .* *.* **:::**:* :. . * : * ::..* *:: .* : : : *..*. * :: : *. . ::.:.: :* :*.***:: ..: * : *:*.. :.: . . * *::::*: * **: : . :: :. . . .: * : : : :. . * *. : * ", "identical_positions": 183, "similar_positions": 302, "identity": "17.31%" }, { "cls_id": "homologset.agr.RGD:1308473", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q3KR92-1", "uniprot_id": "TPST1_RAT", "id": "Q3KR92-1", "name": "Protein-tyrosine sulfotransferase 1", "aln": "-MVGKLKQNLLLACLVISSVTVFYLGQHAMECHHRIEERSQPARLENPKATVRTGLDIKANKTFTYHKNMPLIFIGGVPRSGTTLMRAMLDAHPDIRCGEETRVIPRILALKQMWSRSSKEKIRLDEAGVTDEVLDSAMQAFLLEVIVKHGEPAPYLCNKDPFALKSLTYLARLFPNAKFLLMVRDGRASVHSMISRKVTIAGFDLNSYRDCLTKWNRAIETMYNQCMEVGYKKCMLVHYEQLVLHPERWMRTLLKFLHIPWNHSVLHHEEMIGKAGGVSLSKVERSTDQVIKPVNVGALSKWVGKIPPDVLQDMAVIAPMLAKLGYDPYANPPNYGKPDPKILENTRRVHKGEFQLPDFLKEKPQTEQVE--------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70281-1", "uniprot_id": "TPST1_MOUSE", "id": "O70281-1", "name": "Protein-tyrosine sulfotransferase 1", "aln": "-MVGKLKQNLLLACLVISSVTVFYLGQHAMECHHRIEERSQPARLENPKATVRAGLDIKANKTFTYHKDMPLIFIGGVPRSGTTLMRAMLDAHPDIRCGEETRVIPRILALKQMWSRSSKEKIRLDEAGVTDEVLDSAMQAFLLEVIVKHGEPAPYLCNKDPFALKSLTYLARLFPNAKFLLMVRDGRASVHSMISRKVTIAGFDLNSYRDCLTKWNRAIETMYNQCMEVGYKKCMLVHYEQLVLHPERWMRTLLKFLHIPWNHSVLHHEEMIGKAGGVSLSKVERSTDQVIKPVNVGALSKWVGKIPPDVLQDMAVIAPMLAKLGYDPYANPPNYGKPDPKILENTRRVYKGEFQLPDFLKEKPQTEQVE--------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60507-1", "uniprot_id": "TPST1_HUMAN", "id": "O60507-1", "name": "Protein-tyrosine sulfotransferase 1", "aln": "-MVGKLKQNLLLACLVISSVTVFYLGQHAMECHHRIEERSQPVKLESTRTTVRTGLDLKANKTFAYHKDMPLIFIGGVPRSGTTLMRAMLDAHPDIRCGEETRVIPRILALKQMWSRSSKEKIRLDEAGVTDEVLDSAMQAFLLEIIVKHGEPAPYLCNKDPFALKSLTYLSRLFPNAKFLLMVRDGRASVHSMISRKVTIAGFDLNSYRDCLTKWNRAIETMYNQCMEVGYKKCMLVHYEQLVLHPERWMRTLLKFLQIPWNHSVLHHEEMIGKAGGVSLSKVERSTDQVIKPVNVGALSKWVGKIPPDVLQDMAVIAPMLAKLGYDPYANPPNYGKPDPKIIENTRRVYKGEFQLPDFLKEKPQTEQVE--------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9PTE6-1", "uniprot_id": "TPST1_DANRE", "id": "Q9PTE6-1", "name": "Protein-tyrosine sulfotransferase 1", "aln": "-MIGKLKQNLLVACLVISSVTVFYLCRHAMDCHHRIEERSQPL-LSSLHATLRTGQNLST--PFIYNKDMPLIFIGGVPRSGTTLMRAMLDAHPDVRCGEETRVIPRILAMKQMWSRSGREKMRLDEAGVTDEVLDSAMQAFLLEIIVKHGEPANYLCNKDPFALKSLTYLAKIFPHAKFILMVRDGRASVHSMISRKVTIAGFDLSSYRDCLTKWNRAIETMYTQCLEA-ADKCLPVHYEQLVLHPEKWMRTLLRFLNIPWNDAVLHHEELIGKAGGVSLSKVERSTDQVIKPVNVEALSKWVGKIPLDVQRDMAVIAPMLARLGYDPHANPPNYGRPDPLVLDNTRRLQK--------SPEKPNPS-----------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VYB7-1", "uniprot_id": "TPST_DROME", "id": "Q9VYB7-1", "name": "Protein-tyrosine sulfotransferase", "aln": "MRLPYRNKKVTLWVLFGIIVITMFLFKFTELRPTCLFKVDAANELSSQMVRVEKYLTDDNQRVYSYNREMPLIFIGGVPRSGTTLMRAMLDAHPDVRCGQETRVIPRILQLRSHWLKSEKESLRLQEAGITKEVMNSAIAQFCLEIIAKHGEPAPRLCNKDPLTLKMGSYVIELFPNAKFLFMVRDGRATVHSIISRKVTITGFDLSSYRQCMQKWNHAIEVMHEQCRDIGKDRCMMVYYEQLVLHPEEWMRKILKFLDVPWNDAVLHHEEFINKPNGVPLSKVERSSDQVIKPVNLEAMSKWVGQIPGDVVRDMADIAPMLSVLGYDPYANPPDYGKPDAWVQDNTSKLKANRMLWESKAKQVLQMSSSEDDNTNTIINNSNNKDNNNNQYTINKIIPEQHSRQRQHVQQQHLQQQQQQHLQQQQHQRQQQQQQREEESESEREAEPDREQQLLHQKPKDVITIKQLPLAGSNNNNINNNINNNNNNNNIMEDPMADT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :::: : *. * .::* :.: : : . . *.. . :. . : *:::**************************:***:********* ::. * :* :*.:**:***:*.**::**: * **:*.****** ******::** :*: .:**:***::*******:***:*******:****.***:*: ***:***.*: ** : .:*: *:*********.***.:*:**.:***.:******:*.*..**.*******:********: *:*****:** ** :*** *****: *****:****:**:**. : :** :: : : . ", "identical_positions": 192, "similar_positions": 97, "identity": "38.48%" }, { "cls_id": "homologset.agr.RGD:1308474", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P48972-1", "uniprot_id": "MYBB_MOUSE", "id": "P48972-1", "name": "Myb-related protein B", "aln": "----------------------------MSRRTRCEDLDELHYQDVDSDLLEQRDN------------------------------------------RCKVKWTHEEDEQLRALVRQFGQQDWKFLASHFPN--RTDQQCQYRWLRVLNPDLVKGPWTKEEDQKVIELVKKYGTKQWTLIAKHLKGRLGKQCRERWHNHLNPEVKK--SCWTEEEDRIICEAHKVLGNRWAEIAKMLPGRTDNAVKNHWNSTIKRKVDTGGFPAESRDCKP-VYLLLELEDKEQHQGVQPVDGQGSLVSSWPLVPSIVKEESSEEEIAIAATSAKELGHEPVPADLGEVRTPEPPESL-KREYQEFSSPETSLPYKWVVEAANLLIPAVGSSLSEALDLIESDPDAWCDLSKFDLPEEPSTEGSVVSSPVQPQTSQQQQ-EEALQSSQQAATPGPSVTEYRLDGHTISDLSRSSRGELIPISPSTEFGGSGIGTPPSVLKRQKKRRVALSPVTENSASLSFLDSCNSLTPKSTPVKTLPFSPSQFLNFWN--KQDTLELESPSLTSTPVCSQKVVVTTPLHRDKTPLHQKYPSSEVLPDQKYSMDNTPHTPTPFKNALEKYGPLKP---------------------------LPQTP-HLEEDLKEVLRSEAG-------------------MELIIEDDMRPEKQKRKPGLRRSPIKKVRKSLALDIMDEDG-----KLMSSTMPKPLSLPTSVTPSSCGFTSPGSK-EGNSLLNQGFLQAKPEKVVAAQ--KTRSHIPTPAPMTHAWKTVACGGTKDQLFMQEKARQLLSRLKSSHTSRTLILS-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LKK8-1", "uniprot_id": "A0ABK0LKK8_RAT", "id": "A0ABK0LKK8-1", "name": "Myb-related protein B", "aln": "-----MMVVPVFERLRQENCQPELWRPCFKKKKVGEELDELRYQDTDSDLLEQRDN------------------------------------------KCKVKWTHEEDELLRALVRQFGQQDWKFLASHFPN--RTDQQCQYRWLRVLNPDLVKGPWTKEEDQKVIELVKKYGTKQWTLIAKHLKGRLGKQCRERWHNHLNPEVKK--SCWTEEEDRIICEAHKVLGNRWAEIAKMLPGRTDNAVKNHWNSTIKRKVDTGGFPNESRDCKP-VYLLLELEDKDYQQNVQPVEGPGSLVSSWPLAPSTVKEEESSEEEAAVATTSKEHKQEPVPTDLGEVRTPEPLEFL-KREYQEESSPETSLPYKWVVEAANLLIPAVESSLSEALDLIESDPDAWCDLSKFDLPEEPSAEGSVNSSPVQLQTPQQQQQHQQALSFHQAATPGPSVTEYRLDGHTISDLSRSSRGELIPISPSTEFGGSGIGTPPSVLKRQKKRRVALSPVTENSASLSFLDSCNSLTPKSTPVKTLPFSPSQFLNFWN--KQDTLELESPSLTSTPVCSQKVVVTTPLHRDKTPLHQKYP-SFVTPDQKYSMDNTPHTPTPFKNALEKYGPLKP---------------------------LPQTP-HLEEDLKEVLRSEAG-------------------IELIIEDDMRPEKQKRKPGLRRSPIKKVRKSLALDIVDEDG-----KMMSSTSPKTLSLPTSVPSSSSGFILPGIK-EDNSLLNQGFLQAKPEKVVATQ--KPRSHIPAPAPMTRAWKTVACGGTKDQLFMQEKARQLLGRLKSSHTSRTLILS-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P10244-1", "uniprot_id": "MYBB_HUMAN", "id": "P10244-1", "name": "Myb-related protein B", "aln": "----------------------------MSRRTRCEDLDELHYQDTDSDVPEQRDS------------------------------------------KCKVKWTHEEDEQLRALVRQFGQQDWKFLASHFPN--RTDQQCQYRWLRVLNPDLVKGPWTKEEDQKVIELVKKYGTKQWTLIAKHLKGRLGKQCRERWHNHLNPEVKK--SCWTEEEDRIICEAHKVLGNRWAEIAKMLPGRTDNAVKNHWNSTIKRKVDTGGFLSESKDCKPPVYLLLELEDKDGLQSAQPTEGQGSLLTNWPSVPPTIKEEENSEEELAAATTSKEQ--EPIGTDLDAVRTPEPLEEFPKREDQEGSPPETSLPYKWVVEAANLLIPAVGSSLSEALDLIESDPDAWCDLSKFDLPEEPSAEDSINNSLVQLQASHQQQ----VLPPRQPSALVPSVTEYRLDGHTISDLSRSSRGELIPISPSTEVGGSGIGTPPSVLKRQRKRRVALSPVTENSTSLSFLDSCNSLTPKSTPVKTLPFSPSQFLNFWN--KQDTLELESPSLTSTPVCSQKVVVTTPLHRDKTPLHQKHA-AFVTPDQKYSMDNTPHTPTPFKNALEKYGPLKP---------------------------LPQTP-HLEEDLKEVLRSEAG-------------------IELIIEDDIRPEKQKRKPGLRRSPIKKVRKSLALDIVDEDV-----KLMMSTLPKSLSLPTTAPSNSSSLTLSGIK-EDNSLLNQGFLQAKPEKAAVAQ--KPRSHFTTPAPMSSAWKTVACGGTRDQLFMQEKARQLLGRLKPSHTSRTLILS-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TZ83-1", "uniprot_id": "A0AB32TZ83_DANRE", "id": "A0AB32TZ83-1", "name": "", "aln": "----------------------------MSWWARGEDEEEALCQDTDSDVADQRDCG-----------------------------------------KVKVKWTQEEDDKLRKLVLNVGSNDWKYIAGFLPN--RSEHQCQHRWFKVLDPDLVKGPWTKEEDEKVIELVKKYGNKQWAMVAKHLKGRLGKQCRERWHNHLNPDVKK--SSWTPDEDLIIYKAHRVLGNRWAEIAKLLPGRTDNAVKNHWNSTIKRKVETG-FYSG---VDTTLHVLQQTDPEELLSEEVEISCDG--------ASEELPVECSKREPEEKATAPPQK--------ASSPKTP-------KASTSPKSEGGDSNVSTWVMDSSGFLSPSAAPTLKEVMELMDGDLEGWCTMSDFDLPEES-------------QSSELLQ--------------------FRLEGSALQELSKGSKGELIPISP----GG---ATPPSILSRRSRRRIALSP-----------DPNDSMTPKSTPVKILPFSPSQFLNMWT--KQDTLDLENPSLTSTPVCSQKAVVTTPLHRDKTPLTQKENSLFITPNHKSDLDTMPRTPTPFKNAMEKYGPLRP---------------------------LPPTP-NLEEDLKEVLRSEAG-------------------IELIVEDEAPAEKKRKQ--VYRPPMKKVRKSLALDVIDCSESVAARKQQIKATVKPSQKPQTVQPEPP-VSSCAVK-EEN-VLDQGFILGPNESGPASKPVLATPKTISPLPMSAAWETVVCGRTKDQLFMTEKARRYLRSLKSHTPNRALILS-----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P04197-1", "uniprot_id": "MYB_DROME", "id": "P04197-1", "name": "Myb protein", "aln": "----------------MASASTENGEELMNYGSNSDSEESEYSENEDTQVCDKDSQQNSNADSGYPLDSPELQDSKTTGQKGQNKSGKTSIGAVHPNYGFGKRWSKSEDVLLKQLVETHG-ENWEIIGPHFKD--RLEQQVQQRWAKVLNPELIKGPWTRDEDDMVIKLVRNFGPKKWTLIARYLNGRIGKQCRERWHNHLNPNIKK--TAWTEKEDEIIYQAHLELGNQWAKIAKRLPGRTDNAIKNHWNSTMRRKYDVE---------RRSVNASGSDLKSSRTHLITLIKSGG--------ISKCMNNMQHNKESGGEAVNKSEN--------ADGASVTAVKGGDLAQESQDDHQKGSNLAHLSMQHLIKLTMPRQTPIILKRTRKHIPETHHQAGCSSSET--------------------------------------------FNQEEAAGNARSR----------------------PPS-------------------------------SPVISPIKSLPFSPSHFL-------------KSPCLTTFEDMDLRASTPVTKVYNRVGMEIKKEMETSSIETPHKSQLGPRTPTPFKKALAAIGKKRDGRRY-----------------------EPSSPSSLVEDLAEIIHEEHLSNSLTA-----------NNSKMMGAADQNSTLSTEYNAQSPPHMKRARKSLLSTWSSNHPYN--AGSAKRIQPFETETPSKFLTSPGDILKDTLCSEQDLPFDEGRKENRPFHNRRIN--KYRGGLTYDHVIDPKWARVACGKSRDQMFMEEQAYACLKNLSCISRSLNFEKQKCLVNSFDRFGSL----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P22035-1", "uniprot_id": "BAS1_YEAST", "id": "P22035-1", "name": "Myb-like DNA-binding protein BAS1", "aln": "MSNISTKDIRKSKPKRGSGFDLLEVTESLGYQTHRKNGRNSWSKDDDNMLRSLVNES---------------------------------------AKELGYENGLEDVKTIQQSNHLSKCIAWDVLATRFKHTVRTSKDVRKRWTGSLDPNLKKGKWTQEEDEQLLKAYEEHGP-HWLSISMDIPGRTEDQCAKRYIEVLGPGSKGRLREWTLEEDLNLISKVKAYGTKWRKISSEMEFRPSLTCRNRWRKIITMVVRGQASEVITKAIKENKNIDMTDGKLRQHPIADSDIRSDSTPNKEEQLQLSQQNNPSLIKQDILNVKENESSKLPRLKDNDGPILNDSKPQALPPLKEISAPPPIRMTQVGQTHTSGSIRSKVSLPIEGLSQMNKQSPGGISDSPQTSLPPAFNPASLDEHMMNSNSISDSPK---HAYSTVKTREPNSSSTQWKFTLKDGQGLSISN-GTIDSTKLVKELVDQAKKYSLKISIHQHIHNHYVTSTDHPVSSNTGLSNIGNINGNPLLMDSFPHMGRQLGNGLPGLNSNSDTFNPEYRTSLDNMDSDFLSRTPNYNAFSLEATSHNPADNANELGSQSNRETNSPSVFYPQANTLIPTNSTATNNEIIQGNVSANSMSPNFNGTNGKAPSSTASYTTSGSEMPPDVGPNRIAHFNYLPPTIRPHLGSSDATRGADLNKLLNPSPNSVRSNGSKTKKKEKRKSESSQHHSSSSVTTNKFNHIDQSEISRTTSRSDTPLRDEDGLDFWETLRSLATTNPNPPVEKSAENDGAKPQVVHQGIGSHTEDSSLGSHSGGYDFFNELLDKKADTLHNEAKKTSEHDMTSGGSTDNGSVLPLNPS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .. . :: *. : . . . .: :: *. :. : . * .:: : ** *:*:* ** **::**: ::: .:.* :* :: : ** .** :*: : *.* * ** .** : . *.:* :*:. : *.. : :*:*.. : . : . : . . . . : . . .. . :. . * . . . :. :*. :: : *: . .. . : . : ..:*: * . * :. . *: . . : . * :*. . . . . . . : . . : . : . *: * * . ", "identical_positions": 46, "similar_positions": 126, "identity": "5.38%" }, { "cls_id": "homologset.agr.RGD:1308476", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K2W1-1", "uniprot_id": "A0A0G2K2W1_RAT", "id": "A0A0G2K2W1-1", "name": "Fibrocystin", "aln": "VMPAWRISLLSVELLLLANAYSSFRIEPTEGSLAGGTWITLVFDGLETSILYPNNGSQLAIDLVNV--ATPALK-IPCDISPLFVDLPVVTCQTRSLPSEAPEGLYSLEIRSGDQLLGSPCARLLDNCTFKFSKEQTPVLYQVNPSSGVPGEVVHVYGWVITDRMEIFDPDVDYMESPLILEAGGDKWLTPCSLINRKTGICFPIQEEHGLGTVQCRVEGSYIGSQNVSFSVFNKGRSMVHKEAWLISAKQELFLYQTYPEIHSVFPKVGSLGGRTDITITGDFFDPSARVTIAGIPCDIRHVSPRKIECTTRAPGNGARLTAPQAGNRGLLFEVGNAVKDEELTEATPGYRWQIVPNASSPSGFWSKEGRPFRARLSGFFVAPETNNYTFWIQADSQAFLRFSSSEEPRMKVEVASIAVGTADWFDSWEQNGNEGSWQQKTNKLELQGGAKYYLEAEQHGIAPSRGMRIAVQIHNTWLNPDVVNTYLLEKHQIRAQAQRLPEIQVLNMSGKGNFFLTWGNVSSQPVPANATAQQIQTIIEELLVVKCNLVPLSARVLLWLGFEQGLDGSRSDGVLTSSTEPFCGRFSLGQLRHLILSPGAVSKGYQLDRYPYLCFAYRGHMNRTLDMTVSFLFGFQNVMKNITCDWSLMEPHPESWHFTCNNLWDTCVRHSEELQSSLANTPLLVHRIDIFPVVPEADLLYVDEIILADTNVTVSQADSGVARPGGNVVESVSVVGVPPVYSIASWMAGCGSELPLITACYVPTQGTGEGSELIEVTAKRLQRTSPPLGGHFSLHLSDTVIPDVPVHVSARQLHKLLQDNADESTSGYLNADDFIVTKDQNSCYEHVWTLSWTTQIGDLPNFIRVSDQNLTGLNPTITARVVYDGGVFLGPILGDTLATANQQTQVTVQVNDIPAHCSGSCSFQYQRASTPSVDCVWYSLGSDVNLLVHFTGNGFPRDAQFLQVTVINTSCEVIFSNETNVACELALLPVGVHRVFMLVRPSGLALNASGEGLFLRVEPRLDAVEPSTGAEIGGWWVTLRGSSLEGVSLVLFGTRSCVIDVIRSNSQQIQCKVPPRGKDGYTVNVTVINGDHSTVLARAFTYVSSLNPVIVSLSRNRSNIAGGEILFLGMTLMVNYTDLNVQIYIQNTSAQVLAKTAWGLEVLLPPLLPGIYVISAFINGISIRSQGVDLHIQYLTEVFSMEPCSGSLLGGTILRLSGAGLGRDPALIRVLVDNRPCDTVKLTEVNIWCETPRVLLPPRADVLTVPASVEIWAGNT--------SFVGKAFIFTYEAAATPVVTAMWGELMNNSVRFYVEGNNLSDSVILLGSLKCDLQVQLFGDNMNLSGCSLLLHSLEAGVYALQVRHKRMGFANMSAVPQKFELSPQIIDIFPTHGSIYGGTVLTVKGTAFRSRRRSVHVDLSGPFTCVILSLGDHTVLCQTKFVGDQFSETSLALNITVLVNGLTSKCEGNCTLFLEEAATPIVDALTISISGSLTTVLMRGQRLG-SAGEPTAFVDGQLLCHTTFFNTSYVACQMRDLAPGFHYLSAVRTSAGYACLNSVSRNFFVVPQVFDYFPKDFSIHGGSLLTIKGTTLRGWKTTFVYVGQQACLTVNISSEFIQCIVPAGNGSAALEIDVDGVLYHMGFVDYSSIFTPELLSVSRSHDILTFTVARISGAANVDILIGTSPCLDVAGNRTILRCMVPLLPAGEYAVTGYDHSRGWVSSTLILVLRATVTSVTENYGCLGGRLLHVLGAGFSPGNISAAVCGAPCQVLANATVSAFSCLVLPLDASLAFLCNLRHAEDSCGVSRPTYLQCDLTVSVGMERLPGSWPYVYLCEESSQGLFVPDHQ---IFLSFSGLFLSPKVERDEVLIYNSSCNITMETEAEMECGTPNQPITAKITEIQKSRGQNTQGNFSFQFCRRWSRPHSWFPHRVPQDGDNVTVETSHLLLLDANTSLLNSLHIKGGKLIFMEPGPIDLRAHSILITDGGELHIGSEDKPFQGKARIKLYGSVHSTSFFPYGVKFLAVRNGTLSLHGSVPEVTFTYLRAAACAGDTVLALEEAVAWHPGDEAVISSGATVEGAEATEEVVVVETVHDADLHLRNPLRYSYNFTENWVTGVNHILKATVALLSRNIIVQGNLTLERVKLLDSCQEAGAAEGNLKHCLYSKSEKMLGARNLGARVIIQSFPEEPSLVKLKGVQFRDLGQAFHKHLSSLTLVGAMRGSYLHSCSMWGSFSRGLSIHRTWGLKVENNIFYKIVGHALLVGSYMDRSFSTSEAVIGRKNGWWEEGSMIRNNVIINVSGAEGLSSSEMLAPAGIYTFSPTSAIEGNRVCAAGYGYVLHLVTSQTVQAPLLSFNWNTAHSCTRYGLLVYPEFQPPWNNDTGFTLFQNFMVWGSAGGAQIFRSNNLHLRNFQVYACRDFGIDILESDTNTLVTDSFLLGHFTHEGSLCMSVGIKTPKRWGLTISNTTFVNFDLN-CVAIRTCSGCSQGQGGFPVKTRQLKFVNSSNLVAFPFPHAAVLQDLDGSLSGKNGSHVLASMETLSDTCLTNASFSQIVSGSVCGEAVLFHRMSIGLAKSLDVPKNLTMTDIRNRTITINYVDDTLSNSYGWMALLLDQETYLLQFEGPWTDGSLQYSATFDNFAPGNYLLLMHRDLLPYPDILLRCGSRVGQSLPSHPLPSRDGACDWFFHRQLRQLTYLVSGEGQVHVFLQVKHGAPPTVSASTSVSESALKWSLPETWQDVEKGWGGYNHTIPGPGDDVLILPNKTVLVDTDLPVLRCLYVMGTLEFPVDRSNVLSVACLLIAGGELKVGTLENPLGKDQRLLILLRASEEIFCDRFDGIRVDPGTIGVYGKLRLHSAYPKKSWVHLGADIAPGNERIIVHNAVDWQPHDKIVLSSSSYEPHEAEVLTVKEVKDHHIRIYERLKHRHIGSAHTLEDSRQICLAAEVGLLTRNIRIQSDSSCRGRLLVGSFRKSSGEEFSGILQLLNVEIQNMGSPLYASIEFTGVSAGSWVISSTVHQSCTVGIHASSSRGMVLNDNIVFGTKGHGIDVEGQNYSLTNNLVILSMQSANSLPWVAGIKVNYAEDIILHGNVVAGSERLGFHVRGHGCSS-EVLWSDNVVHSSLHGIHLYKKREPNNCTGVSGFLAFKNFDYGAMVQTENSVDIQNITLVDNTVGLLAISYVSSAPLRSGSTLQITLRNSVIVATSSSFDCIQDRKAPQSANWTSTDRAPSNPRGGRIGILWPVSASEPNGWPQEPWHKVRGGHSVPGIMKLQDVTFSSFVKSCYSDDLDVCILTNEHSTGIMYPITAERTRMLKIKDKNKFYFLPLQSGKDLVGTICPASSDCEIPRKYLFTDLDGRTLGLSPPVSVFPRIEEGWTGSFFNTGIFREEQKCTFRAMIQGFFCKQTEHAVLILDNVDVTWTIPKFYPLVSITNGFVDTFSIVKDSGLCFPTSSPSTFYSILPTRQMTKVCFPERTPPFLHFFLLANRRASKLILAVFYNEIQSPYVFLDKSFIPPTPVESAFSLLDEPVGANYFDIMNNLLYVVLQGEEAVEIRSSVSIHLALTVTFSVLEKGWEKAVLESLRGFFQIDQNQIRLTLEMPGNKETLKAIANSEGKRKRSCPTVTCAVPSSRYVQRRPLMAEMASFTITPATTLETFSKVIVFEIGDLPNARDSEFIQSLPSNRLQKLAHQVITAQQTGVLENVLGMTVGALLVAQSEGVTGYRNASSLITGNQIYTRPSVVSILVQPSDGEVGIELPIQPRLIFLDEKNERVEALGLPSEPWIISVSLEGTSESMLKGCTQAETQDGYVTFSRLAVLTSGSNWHLVFTVTFPPGTNLTARSKTFAVLPVAGKERSTIILALSLCSVASWVALSCLICCWFKKSKTRKIKPEDISESQAKEQKKNTHISSKPRELQVKTAKEDAMMGEDMRMKVMEGRQNQFSQHSMDGVSKRKVSRRAVPEERTATPALKIPRTT-----CVPGALPQQLTLPEPGNWQEAQQQLLRYQLAGRDQLLLLCPDLRQERQQGQEPSQLNKGSGRCMGLSQEK-ATCVPTETFCLHTAPPETIQ---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9PZ36-1", "uniprot_id": "PKHD1_MOUSE", "id": "E9PZ36-1", "name": "Fibrocystin", "aln": "MMLAWLVSLLSMEVLLLAKPYSSFQFEPAEGSLAGGTWITVVFDGLDRSILYPNNGSQLQIDLVSV--AIPTLR-IPCDVSPAFVDLPVVTCQTRSLPSEADAGPYSLEMRSGEQVLGTPCPGSLDSCTFKFSKDQTPVLYQVYPASGVPGEVVSVYGRVITTWLETFDPDVDYIESPLILEAREDKWLTPCSLINRQTGSCFPIQEEHGLGNVQCRVEGDYIGSQNVSFSVFNKGRSMVHKEAWLISAKQELFLYQTYPEILSVFPKVGSLGGRTDIIITGDFFDPSARVTIAGIPCDIRYVSPRKIECTTRAPGNEARLTAPQAGNRGLRFEVGDATKDVELTEATPGYRWQIVPNASSPSGFWSKEGRPFRARLSGFFVAPQTNNYTFWIQADSQASLCFSSSEEPRTKVEVASVGVGTADWFDSWEQIGNEGSWHQKTTKLELQGGAKYYLEAEQHGIAPSRGMRIGVQIHNTWLNPDVVNTYLLEKHQIRARAQRLPEIQVLHVSGKGNFFLTWGNVSSQPVPANATAQQIQTTIEELLVVKCNLAPFSAHVLLRLGFEQGLEGSRSDGVRTSSTEPFCGRFSLGQLGHLILIPEAADKGYQLDRYPYLCLAYRGHMNKTLDMTVSFLFGFQTIMKNITCDWSLTDPHPESWQFTCINLWDTCLCHSEDIQSSLANTPLLAHRIDIRPVVPEAGLLYVDEIILADTNVTVSQADSGRACPGGNVVESVSVVGVPPVYSISSWLAGCGSELPLITACSVSTEGTGDGSELIEVTAQRLQRTSPPLGGHFFLYLSDTVIPDVPVRMSARQLHKLLQDSADESTSGYLNAGDFTVTEDLNSCYEHVWTLSWTTQTGDLPNFIRVSDQNLTGVNPTVTARVVYDGGVFLGPIFGDMLATANQQTQVAVQVNDIPAYCSGSCSFQYQQESTPSVDHVWYSLGSDVNLLVHFTGTGFPRDTQFLQVTVNKTSCEVLFSNETNVACELALLPVGVHQIFMLVIPSGLAVHASGEDLLLHVEPRLDAVEPSTAAEIGGRWVTLRGSSLEGVSLVLFGTQSCVIDAIRSNSQQIQCKVPPRGKDGYTVNVTVISGDHSTVLARAFTYVSSLNPVIVSLSRNRSSIAGGEILFLGMSLLVNYTDLDVQIHVQDTSAQVLSQTAWGLEVVLPPLVPGIHVISAFINGVSIRSQGVDLYIQYLTEVFSVEPCSGSLLGGTLLSLLGTGLGRDPALIRVLVDNHPCDIVNLTEVNIWCETPPAVLPPRADVLTVLASVEIWAGNTSFFHGP--SLVGKGFTFTYEAAATPVVTAMWGEFRNNSVRFYVEGSNISDSVILLGSLKCELEVQFFGDSMNLSGCFFPLHSLEAGVYTLQVRHKRMGFANMSVVPQKFELSPQIIAIFPTHGSKCGGTVLTVKGMAFSSRKRSVHVDISGPFACMILSLEDHTVLCQTRFVGDQFSEASLALNITVLVNGLTSKCKGNCTLFIEEAATPIVDALTISISGSLTMVLMRGRRLATTADEPIAFVDDQLPCHTTFFNTSHVACQIRDLAPGFHYLSAVHTSAGYACLNSVSRNFFIVPQVLDYFPKDFSIHGGSLLTIKGTALRGWKATVVYVGRQACLTVNFSSDFIQCIVPAGNGSAALEIDVNGVLYHIGLVDYSSIFTPELLSVSRSQDILTFTVARISGAANVDIFIGTSPCLGVAGNRTVLQCMVPLLPAGEYLVTGYDHSRGWASSTLILVLRATVTSVTKNYGCLGGRLLHVLGAGFSPGNISAAVCGAPCQVLANATVSAFSCLVLPLHVSLAFLCDLRHAEDSCKVRSSTYLRCDLTVSMGTERLPGSWPYVYLCEESSLCLFEPDHWTESVFPSFSGLFLSPKVERDEVLIYNSSCNITMETEAEMECEMPNQPITAKITEIQKSWGQNTQGNFSFQFCRRWSRPHSWFPQRVPHDGDSVTVETGHLLLLDANTSFLNSLHIKGGKLIFMDPGPIELRAHSILITDGGELHIGSEEKPFQGKARIKIYGSVHSTPFFPYGVKFLAVRNGTLSLHGSVPEVTVTYLQAAAHAGDKVLTLGEAVDWKPGDEAVITSGMTVAGAEAT-EVVVVETVHNADLHLRNPLRYSYDFRENWVAGENPILKPTVALLSRNIIIQGNFTLERVKLLNSCQEANTAKGNLKHCLYSKSEKMLGARDLGARVIIQSFPEEPSFVKLKGVQFRDLGQAFHKHLSSLALVGAMRGSYIQSCSVWNSFSRGLSMHRTWGLKVDSNVFYKIVGHALLLGSYLDGRFSTSETVTGRKNGWWEQGSTIRNNVIISVSAAEGLSGSEMLAPAGIYTFSPTNVMEGNRVCAAGYGYVFHLVTSQTLQAPLLSFNWNTAHSCTRYGLLVYPKFQPPWNNDTGFTLFQNFMVWGSAGGAQIFRSNNLHLKNFQVYACRDFGIDILESDANTLITDSFLLGHFTHKGSLCMSAGIKTPQRWELTISNTTFVNFDGN-CVAIRTCSGCFQGQGGYTVKTRQLKFVNSSNLVAFPFPHAAVLEDLDGSLSGKNGSHVLASMETLSDTCLTNASFSQIVPGSVCGEAVLFHRMSIALANSLDVPKNLTITDISNKTITVNYVEDTLSNYYGWMALLLDQETYSLQFESPWMNRSLQYSATFDSFAPGNYLLIMHRDLPPYPDILLRCGSQVGHSLPFHPLPSQDRACDWFFNRQLRQLTYLVSGEGQVKVFLQLKPGVPPSVSASTSVPESASRWSLPETWQDVEKGWGGYNHTIPGPGDDVLILPNKTVLVDTDLPVLRCLYVMGTLEFPVDRSNVLSVACLLIAGGELKVGTLENPLEKDQRLLIFLRASEEVVCDYFEGIHVDPGTIGVYGKLRLHSAYPKKSWVHLGADIAPGNERIIVHNAVDWQPHDTIVLSSSSYEAHEAEVLTVKEVKGHHIRIYERLKHRHIGSTHTMEDGQQVHLAAEVGLLTRNIRIQPDSSCRGRLLVGSFRKSSGEDFSGVLQLLNVEIQNMGLPLYSSIEFTGVSAGSWVISSTVHQSCSVGIHASSSHGVILTDNVVFGTNGHGIDVEGQNYSLTNNLVILTMQSANSSPWVAGIKVNYAEDIILHGNVVAGSERLGFHVGGHGCSS-EVLWSDNVVHSSLHGLHLYKKHESNNCTGVSGFMAFKNFDYGAMVQTENSVDIQNITLVDNTVGLLAITYVSSALLSSVSTVQITLRNSVIVATSSSFDCIHDRKAPQSANWTSTDRAPSNPRGGRIGILWPVSASEPNAWPQEPWHKVRSRHSVPGIMKLQDVTFSSFVKSCYSNDLDVCILPNEYSTGVMYPITAERTRMLGIKDKNKFYFPVLQSSKDLVGTICPT-LVCEYPRKYLFTDLDGRTLGLPPPVSVFPRTEEEWTGSFLNTGIFREEQKCTFRAMNQGFFCKQTEHAVLILDNVDATWTIPKSHPLVSVTNGFVDTFSIVKDSDLCPPTSSLSTFYSILPTRQMTKVCFPEQTPPFLRFLLLGNQRASKLILAVFYNEIQSPHVFLDKSFIPPTPLESAFSLLAEPSGANYFDIMNNLLYVVLQGEEPVEIHSSVSIHLALTVTFSVLEKGWERAMLESLSDFFQIDPNQIRLTLEMPGNKETLEAIANSERKRKRNCPSVTCGGPSIRYGQRRPLMAEMTSLKITPATTLETFSKVIVIEVGDLPNIRNSEPIQSLPSNRLQRLVNQVITAQQTGALENVLGMTVGALLVTQSKGVTGYRNASSLITGNLIYTRPSELSILVQPSDGEVGIELPVQPRLVFLDEKNERVESLGLPSEPWIISVSLEGASESVLKGCTLAETRDGYVTFSRLAVLISGSNWHLFFTVISPPGTNFTARSRTFVVLPVASKERSTIILALSLCSVASWVALSCLVCCWFKKSKTRKIKPEDISESQAKEQKKNTHNSSKPRGLQAKTAKENTLMGEDMRMKVMQGMQSQFPQHSMDGVSKRKVSRLAVTEERTTTPAPKIPRIT-----CVPGSLAQQLTLQEPGNWQEAQQQLLRYQLAGRNQLLLLRPDLRQERKQGQEPSQLDKGSD-CTGLSQEK-ATCIPTETFSLHTAPPETIQ---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P08F94-1", "uniprot_id": "PKHD1_HUMAN", "id": "P08F94-1", "name": "Fibrocystin", "aln": "-MTAWLISLMSIEVLLLAVRHLSLHIEPEEGSLAGGTWITVIFDGLELGVLYPNNGSQLEIHLVNVNMVVPALRSVPCDVFPVFLDLPVVTCRTRSVLSEAHEGLYFLEAYFGGQLVSSPNPGPRDSCTFKFSKAQTPIVHQVYPPSGVPGKLIHVYGWIITGRLETFDFDAEYIDSPVILEAQGDKWVTPCSLINRQMGSCYPIQEDHGLGTLQCHVEGDYIGSQNVSFSVFNKGKSMVHKKAWLISAKQDLFLYQTHSEILSVFPETGSLGGRTNITITGDFFDNSAQVTIAGIPCDIRHVSPRKIECTTRAPGKDVRLTTPQPGNRGLLFEVGDAVEGLELTEATPGYRWQIVPNASSPFGFWSQEGQPFRARLSGFFVAPETNNYTFWIQADSQASLHFSWSEEPRTKVKVASISVGTADWFDSWEQNRDEGTWQQKTPKLELLGGAMYYLEAEHHGIAPSRGMRIGVQIHNTWLNPDVVTTYLREKHQIRVRAQRLPEVQVLNVSGRGNFFLTWDNVSSQPIPANATAHLIQTTIEELLAVKCKLEPLWSNILLRLGFERGPEVSNSDGDLTSGTEPFCGRFSLRQPRHLVLTPPAAQKGYRLDQYTHLCLAYKGHMNKILKMIVSFTIGFQNMVKNTTCDWSLTRTSPESWQFDCTDLWETCVRCFGDLQPPPANSPVLVHQINLLPLAQETGLFYVDEIIIADTNVTVSQADSGTARPGGNLVESVSVVGSPPVYSVTSWLAGCGTELPLITARSVPTEGTEEGSGLVLVTTQRRQRTSPPLGGHFRIQLPNTVISDVPVQISAHHLHQLLQNNADDFTSRYLNASDFTVKEDLYTCYEHVWTLSWSTQIGDLPNFIRVSDENLTGVNPAAATRVVYDGGVFLGPIFGDMLATANQHTQVVVRVNDVPAHCPGSCSFQYLQGSTPCVHSVWYSIDGDINLMIYITGTGFSGDSQFLQVTVNKTSCKVIFSNQTNVVCQTDLLPVGMHRILMLVRPSGLAISATGEDLFLNVKPRLDMVEPSRAADIGGLWATIRGSSLEGVSLILFGSYSCAINVATSNSSRIQCKVPPRGKDGRIVNVTVIRGDYSAVLPRAFTYVSSLNPVIVTLSRNISNIAGGETLVIGVARLMNYTDLDVEVHVQDALAPVHTQSAWGLEVALPPLPAGLHRISVSINGVSIHSQGVDLHIQYLTEVFSIEPCCGSLLGGTILSISGIGFSRDPALVWVLVGNRSCDIVNLTEASIWCETLPAPQIPDAGAPTVPAAVEVWAGNRFFARGPSPSLVGKGFTFMYEAAATPVVTAMQGEITNSSLSLHVGGSNLSNSVILLGNLNCDVETQSFQGNVSLSGCSIPLHSLEAGIYPLQVRQKQMGFANMSVVLQQFAVMPRIMAIFPSQGSACGGTILTVRGLLLNSRRRSVRVDLSGPFTCVILSLGDHTILCQVSLEGDPLPGASFSLNVTVLVNGLTSECQGNCTLFIREEASPVMDALSTNTSGSLTTVLIRGQRLATTADEPMVFVDDQLPCNVTFFNASHVVCQTRDLAPGPHYLSVFYTRNGYACSGNVSRHFYIMPQVFHYFPKNFSLHGGSLLTIEGTGLRGQNTTSVYIDQQTCLTVNIGAELIRCIVPTGNGSVALEIEVDGLWYHIGVIGYNKAFTPELISISQSDDILTFAVAQISGAANIDIFIGMSPCVGVSGNHTVLQCVVPSLPAGEYHVRGYDCIRGWASSALVFTSRVIITAVTENFGCLGGRLVHVFGAGFSPGNVSAAVCGAPCRVLANATVSAFSCLVLPLDVSLAFLCGLKREEDSCEAARHTYVQCDLTVAMATEQLLESWPYLYICEESSQCLFVPDHWAESMFPSFSGLFISPKLERDEVLIYNSSCNITMETEAEMECETPNQPITVKITEIRKRWGQNTQGNFSLQFCRRWSRTHSWFPERLPQDGDNVTVENGQLLLLDTNTSILNLLHIKGGKLIFMAPGPIELRAHAILVSDGGELRIGSEDKPFQGRAQITLYGSSYSTPFFPYGVKFLAVRNGTLSLHGSLPEVIVTCLRATAHALDTVLALEDAVDWNPGDEVVIISGTGVKGAKPMEEIVTVETVQDTDLYLKSPLRYSHNFTENWVAGEHHILKATVALLSRSITIQGNLTNEREKLLVSCQEANAPEGNLQHCLYSMSEKMLGSRDMGARVIVQSFPEEPSQVQLKGVQFQVLGQAFHKHLSSLTLVGAMRESFIQGCTVRNSFSRGLSMCGTLGLKVDSNVFYNILGHALLVGTCTEMRYISWEAIHGRKDDWSGHGNIIRNNVIIQVSGAEGLSNPEMLTPSGIYICSPTNVIEGNRVCGAGYGYFFHLMTNQTSQAPLLSFTQNIAHSCTRYGLFVYPKFQPPWDNVTGTTLFQSFTVWESAGGAQIFRSSNLRLKNFKVYSCRDFGIDVLESDANTSVTDSLLLGHFAHKGSLCMSSGIKTPKRWELMVSNTTFVNFDLINCVAIRTCSDCSQGQGGFTVKTSQLKFTNSSNLVAFPFPHAAILEDLDGSLSGKNRSHILASMETLSASCLVNSSFGRVVHGSACGGGVLFHRMSIGLANTPEVSYDLTMTDSRNKTTTVNYVRDTLSNPRGWMALLLDQETYSLQSENLWINRSLQYSATFDNFAPGNYLLLVHTDLPPYPDILLRCGSRVGLSFPFLPSPGQNQGCDWFFNSQLRQLTYLVSGEGQVQVILRVKEGMPPTISASTSAPESALKWSLPETWQGVEEGWGGYNNTIPGPGDDVLILPNRTVLVDTDLPFFKGLYVMGTLDFPVDRSNVLSVACMVIAGGELKVGTLENPLEKEQKLLILLRASEGVFCDRMNGIHIDPGTIGVYGKVHLYSAYPKNSWTHLGADIASGNERIIVEDAVDWRPHDKIVLSSSSYEPHEAEVLTVKEVKGHHVRIYERLKHRHIGSVHVTEDGRHIRLAAEVGLLTRNIQIQPDVSCRGRLFVGSFRKSSREEFSGVLQLLNVEIQNFGSPLYSSVEFSNVSAGSWIISSTLHQSCGGGIHAAASHGVLLNDNIVFGTAGHGIDLEGQAYTVTNNLVVLMTQPAWSTIWVAGIKVNQVKDINLHGNVVAGSERLGFHIRGHKCSSCELLWSDNVAHSSLHGLHLYKESGLDNCTRISGFLAFKNFDYGAMLHVENSVEIENITLVDNTIGLLAVVYVFSAPQNSVKKVQIVLRNSVIVATSSSFDCIQDKVKPHSANLTSTDRAPSNPRGGRIGILWPVFTSEPNQWPQEPWHKVRNDHSISGIMKLQDVTFSSFVKSCYSDDLDVCILPNAENSGIMHPITAERTRMLKIKDKNKFYFPSLQPRKDLGKVVCPE-LDCASPRKYLFKDLDGRALGLPPPVSVFPKTEAEWTASFFNAGTFREEQKCTYQFLMQGFICKQTDQVVLILDSADAIWAIQKLYPVVSVTSGFVDVFSSVNANIPCSTSGSVSTFYSILPIRQITKVCFMDQTPQVLRFFLLGNKSTSKLLLAVFYHELQSPHVFLGESFIPPTLVQSASLLLNESIGANYFNIMDNLLYVVLQGEEPIEIRSGVSIHLALTVMVSVLEKGWEIVILERLTNFLQIGQNQIRFIHEMPGHEETLKAIADSRAKRKRNCPTVTCTSHYRRVGQRRPLMMEMNSHRASPPMTVETISKVIVIEIGDSPTVRSTGMISSLSSNKLQNLAHRVITAQQTGVLENVLNMTIGALLVTQSKGVIGYGNTSSFKTGNLIYIRPYALSILVQPSDGEVGNELPVQPQLVFLDEQNRRVESLGPPSEPWTISASLEGASDSVLKGCTQAETQDGYVSFYNLAVLISGSNWHFIFTVTSPPGVNFTARSKPFAVLPVTRKEKSTIILAASLSSVASWLALSCLVCCWLKRSKSRKTKPEEIPESQTNNQNIHIHISSKRRESQG-PKKEDTVVGEDMRMKVMLGKVNQCPHQLMNGVSRRKVSRHIVREEEAAVPAPGTTGITSHGHICAPGAPAQQVYLQETGNWKEGQEQLLRYQLAGQNQLLLLCPDFRQERQQLPGQSRLSKQSG-SLGLSQEKKASCGATEAFCLHSVHPETIQEQL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ** :**:*:*:**** : *:::** ***********::****: .:********* *.**.* . *:*: :***: * *:*******:***: *** * * ** * *::.:* . *.******* ***:::** *.*****::: *** :** :* ** *.:*::**:**** ***:********: * *:****:****.:**:***.***************:*****:********:******:.** ****:.*******:* ******* **:***********:**************: .***:**.***** ****:*.:. ******************** ****:**:*************:************** * ** ***** **:***:.************ :**:*:*** **** *** ******:***********.*************.*** ******.:******:***::**:*******.******:******: *** *****.***:* *: :.:** ****:* : *.*** **.********** * **:* * *..***:**:*.:**:**:****: *.* *** :***.::** ****** . ****:* * :**:**: ::*.. **:*:*.*:*:: *:. *:.*:******:************* * ****:******** *****::**:****:******* *.*:** :** *: **::* *********** : *.:***.****::**::**:***:.**: ** ****.** *.:* :**********:** ***********:****:**: ::*************:** ******:***.*:***:**:*.******* : ***.*. ****:..*:**::::**.**. *:******* :***:*:***:***.*: *****:*:::*** *****: *:**.*:*.*:**** **** .*:*** *.*:**********:***: **.*:. ***.:************ ****** **:*:**.**************:**** *.***** *.:*:: ::*****:*::::*:: * * :::****** **** .*:: **. ***:**:******:*********:***.*******:* : * *:.*****: ***.*:.** *:***..***** . * *.. ** *:**:**** *:***.* * ************ **: *.*: ::* *.*:*:******.*:*:::.* * ..:.**** : *******:*.****:*:*******.* *:* : *:*: ***::** ***:***:* : **:***:**:****:*:**** ***:***. : ** :. :*::**:*********:*:******:.* *:*::***: . ***** **:**:**. :*.** .***.** *:.****:*:*.** ****** ****.. * **** ..***:*:::***:.****:**:********:** *** ::* **:.:*:*****:.:::*:****:****.****:*:*: **:*.:.*.. *****:*:*:*.*****:**:******:**:** ***:.*:**:*:*:*:** ****** * *** ***.**:*::. *. :*:**:*:*******:**:********:*********:*****************..******.*:: **** . **::*****::. *:* ****:*:***** ** *** :* ******:***:************************ ******.*****:* *********:********.*****.*:*:***.****..:*****:***:** *********** ****:****:**::*****:****:*****:*:*.:*** :**.*********************:*** .* *:*:* * *.**:* :** *:****.** ** * **:. *:*.****:::**:*:.*****::* ****:* : ***.*******.* :***:* ** *** *****.:.:***:***** ******:*::*****:******** *:******: ************:****** *:::.*:: .*******: * ****:.*:**:*:*****:*: : : : *:: ***:.* .*. *******.**.*****..***:*:*** ***..:******.*****.:**:*.** *******. * *********:***:*****:* ** ****.* ** **********.**:*:**:**:*******:****:** :***:*****:*:****** *****:** * :********* ********.* *****:.*** ****.**************:*:********** **:******** :**.*:**.::* **.** .********.**:: :*. :**:** *:* *:*** ***** ************ ** *. * : *********.********::* ** ***********:** *:* * *.:: .*****: ***************:*:*::* * **::*****..*** :********.**:******:**************:*********.:: *******:*************::*************** *:*:***:***** :.** ::**::**********::*:*****:**.*******.*******.:****:***.*********.************.**:*************.*. **.::: ************:**.* ******:******** *:***:**********:* ***:*:**:.******:****:**** ****::*:*::*.**:**** *****:*** *::*****:* *.* * ******** .:** ***************: ** *** *:******.******:****: :*** :***:**********::.****:*:********:****: ** ** * ..:**.****************:*: *:*** ********************* :**** **********. **:.*******************:*******.* .:*:*:********** ********* **. *** .:** * ******.*****:***.*******: * **.**:*:* ********:: : ***:****::.*****..*. *:* * :*:**:*.****.** *: . * .:.* ******** **:***** ::** .*:*:**.*: :***:*****:*:***:***.:****** ::** ** *. *****:**:***********.:**:*.********* .******** .:** * .*:**. ****: ****::***:***:*. ****.**:*** * ****** ** * :*. *:**:*****:*:** *. *.: *.**.**:**.*.::********.*****.**:*****:**:** ** *:**: *** ** ** :************ ***:**:*:****:*.***:** ***** **.****:*:*:***** ***:****:* .**** ******:.*** ***.*:****:.*.****: **:****** **.*****:*****:***:*:**:** ***:*.***:::*: : * *** * * . **::::********* * .* .:: *:***:***** * **.::.** . * *.**: .**: * *.***:*.*:*********::***** **:****:* *:*.* *. . ****** *:* .**:*.**:. ***** ", "identical_positions": 2760, "similar_positions": 842, "identity": "67.68%" }, { "cls_id": "homologset.agr.RGD:1308477", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0JPP1-1", "uniprot_id": "NC2A_RAT", "id": "A0JPP1-1", "name": "Dr1-associated corepressor", "aln": "-------------------------------MPSKKKKYN----------ARFPPARIKKIMQTDEEIGKVAAAVPVIISRALELFLESLLKKACQVTQSRNAKTMTTSHLKQCIELEQQFDFLKDLVASVPDM--------------QGDGEDNHTDGDK--------GPRRGRKPGSSGRK-----NGGTGS----KSKDKKLSGTDSEQEDESEDTDTDGEEETPQAPPQAS---HPPAHFQSP--------PTPFMPFTS-------------------------------------------------------------------PLPLPPAPPG-----------------PSAPEA---------EDEEDYDS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D6N5-1", "uniprot_id": "NC2A_MOUSE", "id": "Q9D6N5-1", "name": "Dr1-associated corepressor", "aln": "-------------------------------MPSKKKKYN----------ARFPPARIKKIMQTDEEIGKVAAAVPVIISRALELFLESLLKKACQVTQSRNAKTMTTSHLKQCIELEQQFDFLKDLVASVPDM--------------QGDGEDNHVDGDK--------GPRRGRKPGSSGRK-----NGGTGS----KGKDKKLSGTDSEQEDESEDTDTDGEEETPQLPPQAS---HPPAHFQSP--------PTPFIPFTS-------------------------------------------------------------------PLPLPPAPPG-----------------PSAADA---------EDEEDYDS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14919-1", "uniprot_id": "NC2A_HUMAN", "id": "Q14919-1", "name": "Dr1-associated corepressor", "aln": "-------------------------------MPSKKKKYN----------ARFPPARIKKIMQTDEEIGKVAAAVPVIISRALELFLESLLKKACQVTQSRNAKTMTTSHLKQCIELEQQFDFLKDLVASVPDM--------------QGDGEDNHMDGDK--------GARRGRKPGSGGRK-----NGGMGT----KSKDKKLSGTDSEQEDESEDTDTDGEEETSQPPPQAS---HPSAHFQSP--------PTPFLPFAS-------------------------------------------------------------------TLPLPPAPPG-----------------PSAPDE---------EDEEDYDS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W2E3-1", "uniprot_id": "Q9W2E3_DROME", "id": "Q9W2E3-1", "name": "", "aln": "-------------------------------MPSKKKKYN----------ARFPAGRIKKIMQSDEEIGKVAQAVPVIISRTLELFVESLLTKTLRITNARNAKTLSPSHMRQCIVSEKRFDFLKELVRNIPDISVAEEAAYNEDDVLRSSPEEQYPDSDTPYDLSLPSTSMRSQANGTAAYMRSMSLNNGAGSGGGAAATKRQFQSQHSTQETPTTSTTLPAKLARSGSMPAYTPRGRPPNHLKKQSVQLDTAIPAPICNYELNKPIVKIDYSHVQMPTANLCTPDASDSGSGSGAGSGAFNFDIAAPVINIDLTNIVAGGAPGSGVPPASIGLPAATPGDNNNVNQMAGKSSAPIIPKATAASATPTETVFELDEDYDNI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40096-1", "uniprot_id": "NCB1_YEAST", "id": "P40096-1", "name": "Negative cofactor 2 complex subunit alpha", "aln": "MADQVPVTTQLPPIKPEHEVPLDAGGSPVGNMGTNSNNNNELGDVFDRIKTHFPPAKVKKIMQTDEDIGKVSQATPVIAGRSLEFFIALLVKKSGEMARGQGTKRITAEILKKTILNDEKFDFLREGLCVEEGQ---------------TQPEEESA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ::.:: * ::**..::*****:**:****: *.*** .*:**:*: *:.*: .::..:.:* ::.. ::: * :::****:: : . . *:: ", "identical_positions": 32, "similar_positions": 47, "identity": "8.38%" }, { "cls_id": "homologset.agr.RGD:1308478", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZH22-1", "uniprot_id": "SWET1_RAT", "id": "D3ZH22-1", "name": "Sugar transporter SWEET1", "aln": "MEAGGVADSFLSSACVLFTLGMFSTGLSDLRHMQRTRSVDNIQFLPFLTTDVNNLGWLSYGVLKGDGTLIIVNTVGAVLQTLYILAYLHYSPQKHAVLLQTATLLAVLLLGYGYFWLLVPDLETRLQQLGLFCSVFTISMYLSPLADLAKIIQTKSTQRLSFSLTIATLLSSTSWSIYGFRLKDPYITVPNLPGILTGFIRLVLFYKY--PPEQDTKYRLLQT----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CXK4-1", "uniprot_id": "SWET1_MOUSE", "id": "Q9CXK4-1", "name": "Sugar transporter SWEET1", "aln": "MEAGGVADSFLSSACVLFTLGMFSTGLSDLRHMQRTRSVDNIQFLPFLTTDVNNLSWLSYGVLKGDGTLIIVNSVGAVLQTLYILAYLHYSPQKHGVLLQTATLLAVLLLGYGYFWLLVPDLEARLQQLGLFCSVFTISMYLSPLADLAKIVQTKSTQRLSFSLTIATLFCSASWSIYGFRLRDPYITVPNLPGILTSLIRLGLFCKY--PPEQDRKYRLLQT----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BRV3-1", "uniprot_id": "SWET1_HUMAN", "id": "Q9BRV3-1", "name": "Sugar transporter SWEET1", "aln": "MEAGGFLDSLIYGACVVFTLGMFSAGLSDLRHMRMTRSVDNVQFLPFLTTEVNNLGWLSYGALKGDGILIVVNTVGAALQTLYILAYLHYCPRKRVVLLQTATLLGVLLLGYGYFWLLVPNPEARLQQLGLFCSVFTISMYLSPLADLAKVIQTKSTQCLSYPLTIATLLTSASWCLYGFRLRDPYIMVSNFPGIVTSFIRFWLFWKY--PQEQDRNYWLLQT----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5EB14-1", "uniprot_id": "SWET1_DANRE", "id": "Q5EB14-1", "name": "Sugar transporter SWEET1", "aln": "MDFL----QLLSCACIIFTVGMFTTGLTDLKKMKATQSADNVQFLPFLTTCLNNLGWLYYGLLKGDGTVIFVNIIGAFLQTVYIATYCHYTKEKRRVYTQTLLMVSVLCVAWVYFSLVISPGEAQLSQLGLTCSVFTISMYLSPLADLLDIMRTKSVERLSFSLTVATFFTSTSWTLYGLQLGDYYIMVPNTPGIFTSLIRFFLFWWFGAVIPQIPSYKLIQI----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7JVE7-1", "uniprot_id": "SWET1_DROME", "id": "Q7JVE7-1", "name": "Sugar transporter SWEET1", "aln": "-MSAVAYDSLLSTTAVISTVFQFLSGAMICRKYIQKKSTGDSSGVPFICGFLSCSFWLRYGVLTNEQSIVLVNIIGSTLFLVYTLIYYVFTVNKRACVKQFGFVLTVLVVVIVYTNRLEDQRDRMIHVTGIVCCIVTVCFFAAPLASLLHVIRAKNSESLPLPLIATSFVVSLQWLIYGILISDSFIQIPNFLGCILSLLQLGLFVLYPPRSYSGHGYKLVEQAVPF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:: :.:: *: * :* :: .:*..: . :**: :. ** ** *..: ::.** :*: * :* * : .*: * :: ** : * : : : *: *.:.*:.:: :***.* .::::*. : *. .* :::. * .* :**: : * :* :.* * . .:::: ** : . * *:: ", "identical_positions": 44, "similar_positions": 79, "identity": "19.38%" }, { "cls_id": "homologset.agr.RGD:1308479", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4ABT4-1", "uniprot_id": "D4ABT4_RAT", "id": "D4ABT4-1", "name": "NADPH-dependent diflavin oxidoreductase 1", "aln": "-MQVPQLLVLFGSQTGTAQDEAERLGREARRRRLGCRVQALDSYSVANLIREPLVIFVCATTGQGDPP--------DNMKNFWRFIFRKSLPSTSLCQMDFAVLGLGDSSYAKFNFVAKKLHRRLL-QLGGNALVPPCLGDDQHELGP--------DAAIDPWVGDLWEKIMTMYPVPLDIPEIPHGVPLPSKFIFQFLQEVPSIGAEELNLASSAPQTPPSELQPFLAPVVTNQRVTGPQHFQDVRLMEFD-ITESNISFAAGDVVLILPSNSEAHTKQFCQLL-----CLDPNQFFTLKPREPGVPYPPGLPQHCTVWHLVSQYLDIASVPRRSFFELLACLSPHALERE-----------KLLEFSSARGQEELWEYCNRPRRTILEVLCDFPHTAGAIPPDYLLDLIPRIRPRAFSIASSLLAHPRRLQILVAVVKYQTRLKEPRRGLCSSWLASLTPGQAGPVRVPLWVRPGSLVFPKTPGTPIIMVGPGTGVAPFRAAIQERVAHGQMGN-----VLFFGCRQRDQDFYWQTEWQELEQRGCLTLVTAFSREQAQK---VYVQHRLRELGPLVWELLDGQGAYFYLAGNAKYMPTDVSEALTAIFQEEGRLS-TTDAAAYLARLQQTLRFQTETWA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2AI05-1", "uniprot_id": "NDOR1_MOUSE", "id": "A2AI05-1", "name": "NADPH-dependent diflavin oxidoreductase 1", "aln": "-MQVPQLLVLFGSQTGTAQDEAERLGREARRRRLGCRVQALDSYSVANLIREPLVIFVCATTGQGDPP--------DNMKNFWRFIFRKSLPSSSLCQMDFAVLGLGDSSYAKFNFVAKKLHRRLL-QLGGSALLPPCLGDDQHELGP--------DAAIDPWVGDLWEKIMVMYPVPLDIPEIPHGVPLPSKFIFQFLQEVPSIGAEELNIASSAPQTPPSELQPFLAPVITNQRVTGPQHFQDVRLIEFD-ITDSNISFAAGDVVFILPSNSEAHTQQFCQVL-----CLDPNQFFTLKPREPGVPDPPGLPQPCTVWNLVSQYLDIASVPRRSFFELLACLSQHALERE-----------KLLELSSARGQEELWEYCSRPRRTILEVLCDFPHTAGAIPPDYLLDLIPRIRPRAFSIASSLLAHPRRLQILVAVVKYQTRLKEPRHGLCSSWLASLNPGQAGPVRVPLWVRPGSLVFPKTPDTPIIMVGAGTGVAPFRAAIQERVAHGQTGN-----FLFFGCRQRDQDFYWQTEWQKLEQKGWLTLVTAFSREQEQK---VYVQHRLRELGPLVWELLDGQGAYFYLAGNAKYLPTDVSEALMSIFQEEGRLS-TADASAYLARLQQTLRFQTETWA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UHB4-1", "uniprot_id": "NDOR1_HUMAN", "id": "Q9UHB4-1", "name": "NADPH-dependent diflavin oxidoreductase 1", "aln": "-MPSPQLLVLFGSQTGTAQDVSERLGREARRRRLGCRVQALDSYPVVNLINEPLVIFVCATTGQGDPP--------DNMKNFWRFIFRKNLPSTALCQMDFAVLGLGDSSYAKFNFVAKKLHRRLL-QLGGSALLPVCLGDDQHELGP--------DAAVDPWLRDLWDRVLGLYPPPPGLTEIPPGVPLPSKFTLLFLQEAPSTGSEGQRVAHPGSQEPPSESKPFLAPMISNQRVTGPSHFQDVRLIEFD-ILGSGISFAAGDVVLIQPSNSAAHVQRFCQVL-----GLDPDQLFMLQPREPDVSSPTRLPQPCSMRHLVSHYLDIASVPRRSFFELLACLSLHELERE-----------KLLEFSSAQGQEELFEYCNRPRRTILEVLCDFPHTAAAIPPDYLLDLIPVIRPRAFSIASSLLTHPSRLQILVAVVQFQTRLKEPRRGLCSSWLASLDPGQ-GPVRVPLWVRPGSLAFPETPDTPVIMVGPGTGVAPFRAAIQERVAQGQTGN-----FLFFGCRWRDQDFYWEAEWQELEKRDCLTLIPAFSREQEQK---VYVQHRLRELGSLVWELLDRQGAYFYLAGNAKSMPADVSEALMSIFQEEGGLC-SPDAAAYLARLQQTRRFQTETWA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PFP6-1", "uniprot_id": "NDOR1_DANRE", "id": "Q6PFP6-1", "name": "NADPH-dependent diflavin oxidoreductase 1", "aln": "-MSGHTVLVLYGSQTGTAQDTAERIGRQAQRRRLRVKVEALDTYNVVNLISESLVVFVCATTGQGDPP--------DNMKKFWRFLFRKSLPADSLSRLDCAVLGLGDSSYPKFNFVAKKLHKRLL-QLGANMLLPVGLADDQHDLGP--------DGVIDPWLLSFWQKTLSLYPPPAGLAPLREEDKLPPRYIFHFLSEVPNKLTEHLQTVDN--KSSPTPLRPFPAPLVFNQRVTHTAHFQDVRHIEFD-ITGSNIEFSAGDTVMMRPCNTSEDVEQLCQLL-----KLDPESYFTLTPTDSSTEVPARLPQPCSIRFLLEHFLDISAVPRRSFFELLATFATDELEQE-----------KLLEFSSAAGQDTLHSYCNRPRRTALEVLTDFPHTTAELSIGRLLDLFPEIQPRSFSIASSLLEHPNRIQILLAVVKYKTMLVKPRKGLCSSWLASLDPSK-GDVYVPLWVKKGSLKFPQDPESPVIMVGPGTGVAPFRSAIQERVAQGKMAN-----VLFFGCRSESKDFYCGSEWQEKVQAGQMILVTAFSRDQEDK---VYVQHRVKEQGKLLWDLIAKKNAFFYIAGNAKQMPTSVCDALKAVFQKEGGMS-ENQAQEMLDGMEKNGRFQSETWS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VSJ5-1", "uniprot_id": "Q9VSJ5_DROME", "id": "Q9VSJ5-1", "name": "NADPH-dependent diflavin oxidoreductase 1", "aln": "----MRLLVLYGSQTGTAQDVAEQIWRESHQLGFQGPVLPFDEYDMTKLIEERLVVFVVATTGDGVEP--------DNMKLAWRFLLKRSLPAQSLQGMQFACLGLGDSSYPKFNYAAKKLSKRLQ-NLGANSVCPVGLCDDQHDYGH--------LGVSLSWTKDLWTALKGISG--LDESKLSNSHQTTVKWSVKELPKDSQIAPMD-NLLWSQKQTAHS------FKILDNQRTTAVDHFQDVRFLRLQ-CQTEDLSWEPGDVLDVQPQNSDEAVQTFFDLIREHSLNFDESTIVEVSSAHQDMPLPIAYSNPLSLLQAAKFVWDLSAKPRQRFLEVLAQNCCDEMEKE-----------KLLEFSSAEGIDDLVAYVNRPRRNLLEVLEDFRHATSSLTLQQLFEMMPLIQPRSFSIASDVSALS--LDLLVAVVEYKTIMHTPRLGLCSNWLKTLKSGT----ELSGVVKRGTMVWPKDLSIPLIMVGPGTGIAPFRSIIQNRLYAQSKGATIGPLVVFFGCRNKAADFHFGNDFSTWTDAKQVEAHTAFSRDQDQK---VYVQHLIAKNGAHLARLIKDLNAYIYVAGNSNNMPKSVKEAFIEILDG---------DADYVELMIKQRRYQEETWA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12181-1", "uniprot_id": "NDOR1_YEAST", "id": "Q12181-1", "name": "NADPH-dependent diflavin oxidoreductase 1", "aln": "MSSSKKIVILYGSETGNAHDFATILSHRLHRWHFSHTFCSIGDYDPQDILKCRYLFIICSTTGQGELPRNVNALKGERPVTFWSFLKRKNLPSNLLNHIQTAMLGLGDSSYPKFNYGIRKLHQRIVTQLGANELFDRLEADDQAMAGSNKGTGLGIESVYFEYEKKVLSFLLSKYPNRKVNGQIIKREELDPEVYLEPASYLQLSDEHANEKFTSTKVIFEGDESLKVGRVNINKRITSEGHFQDVRQFKFSNVDKIQENYEPGDTVTIYPCNTDEDVSRFLANQS--HWLEIADKPLNFTSGVPNDLKDGGLVRPMTLRNLLKYHCDFMSIPRTSFFLKIWTFATDVTKMERGQEQLNDQREKLRQFATDQDMQDLYDYCNRPRRSILEVLEDF--ISVKLPWKYVLDYLPIIKPRYYSISSGPGDPN--IELTVAIVKYKTILRKIRRGICTNYIARLQEGE----QIRYKLQNNHIIKKEFLNKPMILVGPGVGLAPLLSVVKAEISKD--------IKLLFGCRYKDKDYIYKDMLEDWFRKGKIALHSSFSRDEENSPGVKYVQDYLWRLGEEITNLVVNKDAVFFLCGSSGKMPIQVRLTFIEMLKKWGNFSDEETAKKYLKEMEKSDRYIQETW-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :::*:**:**.*:* : : :. :: : . .:. * .:: :.:: :***:* * :. * *: ::.**: * :: * ********.***: :** :*: :**.. : *** * .. : .. : . . . : *:* * ****** :.:. .: .**.: : * *: .. : . . . . . . :: . *: : ** *: : . . : * ** :::: . : * * .****. **** ** : :. ::: :* *:** :**:*. ::: :*:*:::* : * *:*:.:: * . : :: . : : *:*:**.*.*:**: : :: .: ::**** . *: . : .:***:: :. ***. : . * : *: .* :::.*.: :* .* :: ::. : : : *: *** ", "identical_positions": 114, "similar_positions": 172, "identity": "17.76%" }, { "cls_id": "homologset.agr.RGD:1308481", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JT58-1", "uniprot_id": "A0A0G2JT58_RAT", "id": "A0A0G2JT58-1", "name": "", "aln": "MDSPRFPEETVLITGGGGYFGFRLGCALNQKGVRVILFDIIEPAQNLPEGITFVRGDIRCLSDVEAAFQDAD-IACVFHIASYGMSGREQLNKTRIEEVNVGGTENILQACLGRGVPSLVYTSTFNVIFGGQVIRNGDESLPYLPLHLHPDHYSRTKSIAEKKVLEANGLAFKQGDGVLRTCAIRPAGIYGAGEQRHLPRVVSYIERGLFRFVYGDPQSLVEFVHVDNLAKAHILASEALKADKGHIASGQPYFISDGRPVNNFEFFRPLVEGLGYTFPTTRLPLTLIYYFAFLIEMTHLIVGRLYNFQPFLTCTEVYKTGVTHYFSLEKAKSELGYAPQPFDLQEVVEWFKAHGHGRRPRGQDSEFILWDGILVLLLAFSVLTWIPPSTILSL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D665-1", "uniprot_id": "D42E1_MOUSE", "id": "Q9D665-1", "name": "Short-chain dehydrogenase/reductase family 42E member 1", "aln": "MDSPRFPEETVLITGGGGYFGFRLGCALNQKGARVILFDITQPAQNLPEGIKFVCGDIRCLADVETAFQDAEKVACVFHVASYGMSGREQLNKTQIEEVNVGGTENILRACLERGVPRLVYTSTFNVIFGGQVIRNGDESLPYLPLHLHPDHYSRTKSIAEKKVLEANGLAFKQGDGILRTCAIRPAGIYGAGEQRHLPRIVSYIERGLFRFVYGDPQSLVEFVHVDNLAKAHILASEALKADKGHVASGQPYFISDGRPVNNFEFFRPLVEGLGYTFPSTRLPLTLIYCLAFLVEMTHFIVGRLYNFQPFLTRTEVYKTGVTHYFSLEKAKKELGFEPQPFDLQEVVEWFKAHGHGRGAAGQDSEFMLWDGILILLLALSVLTWILPSTTLSI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WUS8-1", "uniprot_id": "D42E1_HUMAN", "id": "Q8WUS8-1", "name": "Short-chain dehydrogenase/reductase family 42E member 1", "aln": "MDPKRSQKESVLITGGSGYFGFRLGCALNQNGVHVILFDISSPAQTIPEGIKFIQGDIRHLSDVEKAFQDAD-VTCVFHIASYGMSGREQLNRNLIKEVNVRGTDNILQVCQRRRVPRLVYTSTFNVIFGGQVIRNGDESLPYLPLHLHPDHYSRTKSIAEQKVLEANATPLDRGDGVLRTCALRPAGIYGPGEQRHLPRIVSYIEKGLFKFVYGDPRSLVEFVHVDNLVQAHILASEALRADKGHIASGQPYFISDGRPVNNFEFFRPLVEGLGYTFPSTRLPLTLVYCFAFLTEMVHFILGRLYNFQPFLTRTEVYKTGVTHYFSLEKAKKELGYKAQPFDLQEAVEWFKAHGHGRSSGSRDSECFVWDGLLVFLLIIAVLMWLPSSVILSL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8DZE7-1", "uniprot_id": "D42E1_DANRE", "id": "A8DZE7-1", "name": "Short-chain dehydrogenase/reductase family 42E member 1", "aln": "MEVNR-KDNSFLITGGGGYFGFRLACALLKTSSKVVLFDVSPPIQDLPEGLIFMRADIRDYAQVEKAVRGSH---CVFHIASYGMSGREQLNRKLIEEVNVKGTENILRACVAHSVPRLIYTSTFNVVFGGQEIKNGDESLPYLPLHLHPDHYSRTKSIAEMQVLKANNLALSNSTGVLRTCALRPAGIYGPGEQRHLPRIVSYIENGIFRFVYGDPDSLVEFVHVDNLVSAHLLAADALTEKQQCRAAGQAYFISDGRPVNNFEFFRPLVEGLGYSFPTLRLPISMIYFFAFLTEMVHFVVGRIYNFQPLLTRTEVYKTGVTHYFSMRKAREELGYEPKLYDLEDVVQWFQARGHGKKRSRSSIRKLILDVFVVVAFVAVLLSCLPVVGQ---", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: * .::.*****.*******.*** :.. :*:***: * * :***: *: .*** ::** *.:.:. ****:************:. *:**** **:***:.* : ** *:*******:**** *:************************** :**:** .:... *:*****:*******.********:*****.*:*:****** ***********..**:**::** .: *:**.************************:**: ***::::* :*** **.*:::**:*****:** *************:.**:.***: .: :**::.*:**:*:***: . . :: * :::. : :* : ", "identical_positions": 233, "similar_positions": 97, "identity": "59.14%" }, { "cls_id": "homologset.agr.RGD:1308482", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q63965-1", "uniprot_id": "SFXN1_RAT", "id": "Q63965-1", "name": "Sideroflexin-1", "aln": "MSGEVPPNINIKEPRWDQSTFIGRASHFFTVTDPKNILLTNEQLENARKVVHDYRQG-IVPAGLTENELWRAKYAYDSAFHPDTGEKMTLIGRMSAQVPMNMTITGCMMTFYRTTPAVLFWQWINQSFNAVVNYTNRSGDAPLTVNELGTAYVSATTGAVATALGLNALT---KHVSP----LIGRFVPFAAVAAANCINIPLMRQRELKVGIPVTDENGTRLGESTNAAKQAITQVVISRILMAAPGMAIPPFIMNTLEKKAFLKRFPWMSAPIQVTLVGFCLVFATPLCCALFPQKSSMSVTSLEDDLQASIQKSHPELRRVYFNKGL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99JR1-1", "uniprot_id": "SFXN1_MOUSE", "id": "Q99JR1-1", "name": "Sideroflexin-1", "aln": "MSGEVPPNINIKEPRWDQSTFIGRASHFFTVTDPRNILLTNEQLENARKVVHDYRQG-IVPAGLTENELWRAKYAYDSAFHPDTGEKMTLIGRMSAQVPMNMTITGCMMTFYRTTPAVLFWQWINQSFNAVVNYTNRSGDAPLTVNELGTAYVSATTGAVATALGLNALT---KRVSP----LIGRFVPFAAVAAANCINIPLMRQRELKVGIPVTDENGTRLGESTNAAKQAITQVVISRILMAAPGMAIPPFIMNTLEKKAFLKRFPWMSAPIQVTLVGFCLVFATPLCCALFPQKSSMSVTSLEDELQASIQRTHPEIRRVYFNKGL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H9B4-1", "uniprot_id": "SFXN1_HUMAN", "id": "Q9H9B4-1", "name": "Sideroflexin-1", "aln": "MSGELPPNINIKEPRWDQSTFIGRANHFFTVTDPRNILLTNEQLESARKIVHDYRQG-IVPPGLTENELWRAKYIYDSAFHPDTGEKMILIGRMSAQVPMNMTITGCMMTFYRTTPAVLFWQWINQSFNAVVNYTNRSGDAPLTVNELGTAYVSATTGAVATALGLNALT---KHVSP----LIGRFVPFAAVAAANCINIPLMRQRELKVGIPVTDENGNRLGESANAAKQAITQVVVSRILMAAPGMAIPPFIMNTLEKKAFLKRFPWMSAPIQVGLVGFCLVFATPLCCALFPQKSSMSVTSLEAELQAKIQESHPELRRVYFNKGL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R5W5-1", "uniprot_id": "F1R5W5_DANRE", "id": "F1R5W5-1", "name": "Sidoreflexin", "aln": "MAATISTSINIKEPRWDQGTFVGRAKHFFTVTDPRNILLSNKQLEKAHQIIQDYKKG-VVAADLTEDELWRAKYVFDSAFHPDTGEKMLLIGRMSAQVPMNMTITGCMMTFYRTTPAVLFWQWINQSFNAIVNYTNRSGDAPITVNQLGTAYVSATTGAVATALGLNALA---KHVSP----LIGRFVPFAAVAAANCINIPLMRQRELKHGIPVTDENDNRLGESSKAAQQAITQVVVSRILMASPGMAIPPFLMNSLEKKAFLKRFPWMSAPIQVGLVGFCLVFATPLCCALFPQKSSMAVSRLEPELQEKIRASHPGVETVYFNKGL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VN13-1", "uniprot_id": "SFXN1_DROME", "id": "Q9VN13-1", "name": "Sideroflexin-1-3", "aln": "MS--PLPRVNIDEPKYDQNSYLGRAKHFFLLTNPLNVLASASKLEEARQIVIKYRAGKDVPECKTIDDVWRAKYLYDSAFHPETGEKQIVIGRMAAQMPMNTIITGGMMAFYKSTPAVVFWQWFNQTFNAIVNYTNRSGTSPISQQQLVTSYCLATSGALVTALSLNHAV---KNMNP----LLGRLVPLVAVGAANCINIPCMRMQELRNGVTLFDEHSNEMGISKKAAVVGISTVILSRIAMAIPGMTLTPVLMNVLEKRGFLAKYPRSNAPIQTLFCGFVLIFATPLGCAFFKQRADIKVDSLESEVRDSIRKKRPELETVWFNKGL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12029-1", "uniprot_id": "FSF1_YEAST", "id": "Q12029-1", "name": "Sideroflexin FSF1", "aln": "MASSVPGPIDLPESRYDLSTYWGRIRHCAEISDPTMLLTTEKDLAHAREIISAYRHG---ELKETTPEFWRAKKQLDSTVHPDTGKTVLLPFRMSSNVLSNLVVTVGMLTPGLGTAGTVFWQWANQSLNVAVNSANANKSHPMSTSQLLTNYAAAVTASCGVALGLNNLVPRLKNISPHSKLILGRLVPFAAVVSAGIVNVFLMRGNEIRKGISVFDSNGDEVGKSKKAAFMAVGETALSRVINATPTMVIPPLILVRLQRGVLKGKSLGVQTLANLGLISVTMFSALPFALGIFPQRQAIHLNKLEPELHGKKDKDGKPIEKVYFNRGI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: ::: *.::* .:: ** * :::* :* : ..* *:::: *: * * :.**** **:.**:**:. : **:::: * :* *:: *...:**** **::*. ** :* . *:: .:* * * *.:.: .**.** . *.:.* ::**:**:.** :*. :*: ** .*:: *:.: *.:. .:* * :** .: . :**: * * *.:.*.:: *:: : : .: : : .. :. * *: .:* *: : : ** ::: . :. *:**:*:", "identical_positions": 84, "similar_positions": 119, "identity": "25.45%" }, { "cls_id": "homologset.agr.RGD:1308485", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LC42-1", "uniprot_id": "A0ABK0LC42_RAT", "id": "A0ABK0LC42-1", "name": "", "aln": "MSMEQDTRALLPTQGTAWATASVPVARLQGPQGDSHQACSQEPHSPPSAEAPYCDLPRCPPALQDPLHTTTCVGQSVDNLGLGLDQEPQRIGSPTTALPAD-----PRNRHRDPEAIPYLEGPAYS------TDEHKDEDPNSNTSSSQDSNTPHDTSNSSSVDWDTVERPG-VVPNRNRLTMMIPRRPQEGLRTDSAQKV----TRSPARGDTAGQRKENSGSGGQSAGQHWVKLRSESGYFSLERQRSGQTQASSGTPPSGPR-TTTQASSAQRDVSQAASAQEAPQTSSLPRNTQRDTQRS----------------------------------------------TPRTSSPSRVSQRDTPRIMSTQ--------------------------------------RKNTPLSSPLRPTPETLKTSAPE--------------DGPHVTSP----------LCAQ--------DSSLNRTTQ--------------------------------------------------------------------------------------------------------------------------------------------------RDSSRTSCAQRNNPRTSSPNRTTQRDNPRTSCAQRNNPRTSSPNRTTQQDNPRTSCAQRNNPRTSSPSRTTQHDNPRTSCAQRDNPRTSSPNRTTQQDNPRMSCAQRNNPRTSSPNRTTQRDNLRTSCAQRNNPRTSSPNRTIHQDNPRTSCVSQNTPRTS----------------------------------------------STQVDKTTASCSRWEHLRSACTQRD----------NPRTLS-QGCTQKDNPGPSSPHRATQGSSSRNPSPHRTNKDIPWASFPLRPTQSDSSRTSSPSRTKQNQVPWASISLRPTQGDKPQTSAPSKLAHNDPPQQ-YSPS----LATSSSSSHNPGHPSASRTSSPLHPAPRGAPQTSLEPSQPPCAVCIGHRDAPRASSPPRYFQYDPFPFFPDPRSSESESPHHEPPYMPPAVCIGHRDAPRATSPPRHTQFDPFPFLPDTSDAEN--ESPQHDPPQFPPPVCIGYRDAPRASSPPRQFPEPS-FFQDLPRASTESLVPSTDSMHEPPHIPTPVCIGHRDAPSFSSPPRQAPEPSLFFQDPPGTSMESLAPSVDSLHGSPLLLPQVCIGHRDAPRASSPPRHPPSDVGILAPSPPPGSSG-SRGSAPPGETRHNLEREEYTMLADLPPPRRLAQRVPEPQAQGSNEGRTRSPGRAEVERLFGQERRKSEAPGAFQARDEGRSQRPSQGQSQ-LRRQSSPAPSRQVTKPSAKQAEPTRQSRTGPPHPKSPEKHSEGDRQLQRIAPPARTSARPPERKAQIERHLESGYTGLRQPLGGWQSREGLSGPQSPNRHPEKNWGSQEEGLSLGGWPELGGPSL------EGIWRGPPQEHRERWGQSEAWEEPPSNGIQGGPPRGQGSLQELPRPHQPPPSPENSWAGPAECFCARQPEAGTAMGWRAEGTSPHQYSAERPPDLDWRDLLGLLRAPEDGAWTRLPRLDWEGLLELLQARLPQKDPTRHSRDPAKAPGPEPGSSDTEDTLKTESQTQPEGWAKATLANGHRPGQQSESPAQLPSPACTSTQWPTTKVTSGPETSPPVALEQIDHLESHS------PPDLG--PEEPEASEPSRGEDSLADQKQADSADKRPAEGKAGSPLKGRLVTSWRMPGDRPALFNPYLLSLGVLRWQRPDLLNFKKGWMSILDEPGE-------------WKKHWFVLTDSSLKYYRDSTAEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTVRPTSAPDVTKLSECNKENTLHGYGTQKSSLKIGEQRTGSEVIGRGGPRKVDGSRQSLDYVELSPLTPSSPQRVRTLSRSTPERPSKQEDLERDLAQRSEERRKWFES-TDSRTPETPSGDGSRRGLGAPLTDDQQSR----LSEEIEKKWQELEKLPLRENKRVPLTALLNQGHSERRGPTSDSHEALEKEVQSLRAQLEAWRLRGEAPQNAPRLQEDSHIPPGYISQEACERSLAEMESSHQQVMEQLQRHHERELQRLQQEKEWLLAEETAATASAIEAMKKAYQEELSRELSKTRSLQQGPDSLRKQHQLDMEALKQELQVLSERYSQKCLEIGALTRQAEEREHTLRCCQQEGQELLRHNQELHSHLSEEIDRLRSFIASQGTGNSCGRSNERSSCELEVLLRVKENELQYLKKEVQCLRDELQVIQKDKRFT-GKYQDVYVELNHIKTRSEREIEQLKEHLRLAMAALQEKEAVRNSLAE--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99KW3-3", "uniprot_id": "TARA_MOUSE", "id": "Q99KW3-3", "name": "TRIO and F-actin-binding protein", "aln": "MSMEQDTRALLPTQGTAWATASAPVARLQGPQGDSHQACSQEPHSPSSAEAPYCDLPRCPPALQNPLRTTTCVGQSVHSLGLGLGQEPQRVWSPTTALPAEGPAAAPKNRHQDSEGIPYLEGLARSSCTDDNDNKDEDEDPNSNTSSSQDSNTPHDTSNSSSVDWDTTERPG-VVPSRNRLTEMIPRRPQEGLRADSARKA----TRSPARGDTAGQRKENSGSGGQSAGQHWAKLRSESGYFSLERQRSGQTQASSGTPPSGPR-GTTQASSAQRDVFQAAPAQEAPQTSSLPRNTQRDTQRS----------------------------------------------TPRTSSPSRVSQRDTPRVMSTQ--------------------------------------RKNTPLSSPLRATPETLKISAPE--------------DGTHVTPS----------PCVQ--------DSSLNRTSQ--------------------------------------------------------------------------------------------------------------------------------------------------RDSSRTPCIQWDNPRASSPNRTTQRDNPRTPCTQRDNPRASSPNRTTQRDNPRTPCTQRDNPRASSPNRTTQRDNPRTPCAQRDNPRAASPNRSTQRDSPRTPCAQRDNPRASSPNRTAQRDNPRTPCAQR--------------DNPRTSCTSQNTPRTP----------------------------------------------STQADKTTASCSKWEHLRSACTQRD----------NPRTFS-QGCTQKDNPGPPSPRRATQGSNSRNPSPHRTNKDIPWASFPLRPTQSDSPRTSSPSRTKQNQVPWASISLRPTQGDKPQTSAPTRLAHNDPPQQ-YSPS----LATTSSSSHNPGHSSASRTSSPLHAAPRGAPQTSLESSQPPCTVCIGHRDAPRASSPPRYFQYDPFPFFPDPRSSESESPHHEPPYMPPAVCIGHRDAPRATSPPRHTQFDPFPFLPDTSDADN--ESPQHDPPQFPPPVCIGYRDAPRASSPPRQFPEPS-FFQDLPRASTESLVPSTDSMHEPPHIPTPVCIGHRDAPSFSSPPRQAPEPSLFFQDPPGTSMESLAPSIDSLHGCPLLPPQVCIGHRDAPRASSPPRHPPSDIGLLAPSPPPGSSG-SRGSAPPGETRHNLEREEYTMLADLPPPRRLAQRGPEPQAQGSNEGRTRSPGRAEVERLFGQERRKSEAPGAFQTRDEGRSQRPSQAQSQ-LRRQSSPAPSRQVTKPSAKQAEPTRQSRTGPPHPKSPDKRPEGDRQLQRTSPPARTPARPPERKAQIERHLESGHTGPRQSLGGWQSQERLSGPQSPNRHPEKSWGSQKEGPSLGGWPELEGPSL------EGIWRGPPQEHREQWGHSEAWEEPPSNGIQGAPPRGQGRLQELSRPHQPTPSSENSWAGPAECSCALQPEASTAVGWRAEGTSPHQRSAERPPDLDWRDLLGLLRAPEDGAWTRLPRLDWEGLLELLQARLPQKDPARHWHDPAKASGPEQGSSGTEDTLKTEPQTQPEGRAKATLANGHRPGQQSESPAQLPSPACTSTQWPTTKVTSGPETSPLAALEQIDHLESHS------PPDLEFQPEEPEASEPSRGEDSRAVQKQADSADKRPAEGKAGSPLKGRLVTSWRMPGDRPALFNPYLLSLGVLRWQRPDLLNFKKGWMSILDEPGE-------------WKKHWFVLTDSSLKYYRDSTAEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTVRPTSAPDVTKLSDCNKENTLHGYGTQKSSLKIGEQRTGSEVIGRGGPRKADGPRPSLDYVELSPLAPSSPQRMRTLSRSTPERPTKQEDLERDLAQRSEERRKWFES-TDGRTPETPSGDGSRRGLGAPLTDDQQSR----LSEEIEKKWQELEKLPLRENKRVPLTALLNQAHNDRRGPTSDSHEALEKEVQSLRAQLEAWRLRGEAPQNAPRLQEDSHIPPGYISQEACERSLAEMESSHQQVMEQLQRHHERELQRLQQEKEWLLAEETAATASAIEAMKKAYQEELSRELSKTRSLQQGPESLRKQHQLDMEALKQELQVLSERYSQKCLEIGALTRQAEEREHTLRRCQQEGQELLRHNQELHSHLSEEIDRLRSFIASQGTGNSCGRSNERSSCELEVLLRVKENELQYLKKEVQCLRDELQVIQKDKRFT-GKYQDVYVELNHIKTRSEREIEQLKEHLRLAMAALQEKEAVRNSLAE--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H2D6-1", "uniprot_id": "TARA_HUMAN", "id": "Q9H2D6-1", "name": "TRIO and F-actin-binding protein", "aln": "--MEEVPGDALCEHFEANILTQNRCQNCFHP-EEAHGARYQELRSPSGAEVPYCDLPRCPPAPEDPLSASTSGCQSVVDPGLRPG--PKRGPSPSAGLPEEGPTAAPRSRSRELEAVPYLEGLTTS------LCGSCNEDPGSDPTSSPDSATPDDTSNSSSVDWDTVERQEEEAPSWDELAVMIPRRPREGPRADSSQRAPSLLTRSPVGGDAAGQKKEDTGGGGRSAGQHWARLRGESG-LSLERHRSTLTQASSMTPHSGPRSTTSQASPAQRDTAQAASTREIPRASSPHRITQRDTSRASSTQQEISRASSTQQETSRASSTQEDTPRASSTQEDTPRASSTQWNTPRASSPSRSTQLDNPRTSSTQQDNPQTSFPTCTPQRENPRTPCVQQDDPRASSPNRTTQRENSRTSCAQRDNPKASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRAARDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRTTQQDSPRTSCARRDDPRASSPNRTIQQENPRTSCALRDNPRASSPSRTIQQENPRTSCAQRDDPRASSPNRTTQQENPRTSCARRDNPRASSRNRTIQRDNPRTSCAQRDNPRASSPNRTIQQENLRTSCTRQDNPRTSSPNRATRDNPRTSCAQRDNLRASSPIRATQQDNPRTCIQQNIPRSSSTQQDNPKTSCTKRDNLRPTCTQRDRTQSFSFQRDNPGTSSSQCCTQKENLRPSSPHRSTQWNNPRNSSPHRTNKDIPWASFPLRPTQSDGPRTSSPSRSKQSEVPWASIALRPTQGDRPQTSSPSRPAQHDPPQSSFGPTQYNLPSRATSSSHNPGHQSTSRTSSPVYPAAYGAPLTSPEPSQPPCAVCIGHRDAPRASSPPRYLQHDPFPFFPEPRAPESEPPHHEPPYIPPAVCIGHRDAPRASSPPRHTQFDPFPFLPDTSDAEHQCQSPQHEPLQLPAPVCIGYRDAPRASSPPRQAPEPSLLFQDLPRASTESLVPSMDSLHECPHIPTPVCIGHRDAPSFSSPPRQAPEPSLFFQDPPGTSMESLAPSTDSLHGSPVLIPQVCIGHRDAPRASSPPRHPPSDLAFLAPSPSPGSSGGSRGSAPPGETRHNLEREEYTVLADLPPPRRLAQRQPGPQAQCSSGGRTHSPGRAEVERLFGQERRKSEAAGAFQAQDEGRSQQPSQGQSQLLRRQSSPAPSRQVTMLPAKQAELTRRSQAEPPHPWSPEKRPEGDRQLQGSPLPPRTSARTPERELRTQRPLESGQAGPRQPLGVWQSQEEPPGSQGPHRHLERSWSSQEGGLGPGGWWGCGEPSLGAAKAPEGAWGGTSREYKESWGQPEAWEEKPTHELP----------RELGK-RSPLTSPPENWGGPAESSQSWHSGTPTAVGWGAEGACPYPRGSERRPELDWRDLLGLLRAPGEGVWARVPSLDWEGLLELLQARLPRKDPAGHRDDLARALGPELGPPGTNDVPEQESHSQPEGWAEATPVNGHSPALQSQSPVQLPSPACTSTQWPKIKVTRGPATATLAGLEQTGPLGSRSTAKGPSLPELQFQPEEPEESEPSRGQDPLTDQKQADSADKRPAEGKAGSPLKGRLVTSWRMPGDRPTLFNPFLLSLGVLRWRRPDLLNFKKGWMSILDEPGEPPSPSLTTTSTSQWKKHWFVLTDSSLKYYRDSTAEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTVRPTSAPDVTKLSDSNKENALHSYSTQKGPLKAGEQRAGSEVISRGGPRKADGQRQALDYVELSPLTQASPQRARTPAR-TPDRLAKQEELERDLAQRSEERRKWFEA-TDSRTPEVPAGEGPRRGLGAPLTEDQQNR----LSEEIEKKWQELEKLPLRENKRVPLTALLNQSRGERRGPPSDGHEALEKEVQALRAQLEAWRLQGEAPQSALRSQEDGHIPPGYISQEACERSLAEMESSHQQVMEELQRHHERELQRLQQEKEWLLAEETAATASAIEAMKKAYQEELSRELSKTRSLQQGPDGLRKQHQSDVEALKRELQVLSEQYSQKCLEIGALMRQAEEREHTLRRCQQEGQELLRHNQELHGRLSEEIDQLRGFIASQGMGNGCGRSNERSSCELEVLLRVKENELQYLKKEVQCLRDELQMMQKDKRFTSGKYQDVYVELSHIKTRSEREIEQLKEHLRLAMAALQEKESMRNSLAE--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B0C4-1", "uniprot_id": "A0A8M3B0C4_DANRE", "id": "A0A8M3B0C4-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTRLEASLQRSESRSVIEMPSRRESANASRRGSISMSRRESVSQQHSETRRETEQSNGRG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IFKRANRFLSQDREQDDGSSSSPVRHYERGHALPANHSPE----RKAAIPFRNPDLGLPSYRRRYDNLSEQAISGLSPQRHMSYSNFRRGDSQSRASPRSGSPRSTNISPQRRGESRSSSYRR----------------------------------------------------------------------------------------------------------------GSSTHGHRMSSQQASGKCTPSRRRDSIATRTSSPSRSSGTNKYADS-YSPAHKRSPSQSSYGHSLDSEKLYKNLKSIVSSAESDGYDERNGWSKR--------------IQSDDGGYNERNHSGRSSRKSGSHRSGYNSRDFSPTGSN---CDTIKSRNTGRNS-----------------RNSGASTPHRN---------YDERDTVKNSTSKNKSRRN--EVYSDISDKQS----------------------------------------------------------------------------------------------------------------------------KSDSRQSLSPTHSPLSPTSPASTPSIAQSRRSRNQAP--------------------TPDLTKSQTLTPETDKPAIDRSRSNIRRGLEALILSENPRSSSQ------------------------------------------------------PAVPEMTIEDYVIIADIP---RSKLYPEEEEAIIVRRR--------------------PQSRSPRRDNQHSYEDGR------------------------------------------------------------------------------------------------YGYEHEVSEERGRGRERERGRDRREKE------------------------------------------RRRLDKEMGGSSKANSTTSGHSQKSNKNGDIRMTNGGHRGQEKPPPMQG---------------------------------------------------------------------------------------------------------------------------------WMYLLDEDEE-------------WRKFWFVITDSGLRYYRDSEAEERDEADGEVYLRHCLRVEEFDADKNYGLQLHMRDGLVTLSAMTSRIRRNWIDTLRRKISFRDSADSIQHLDNSDISDRENSSSQNAPSQTSP-------APREPCSDDGGLYEDEPDITCSPLTN---------------RREAGEGRDREHERRLEDRTKWFQEGVSDREGDDPWDKVELKKGGTPVVLTQLQVPKAKTGPDIEKKWEDFEQLPIGEKRSLVGSQNPQAAN-----------EALQREVLSLRQQIESLRQVRVGALCGP--------------EAPCALRLQQMEEEHRERLKEIHEQHERERRDMETEKQRLLQEEAKNTLQAMEALRKTHQEEIERLKGHGGEELTDPS--IKQQLHESLSLQRELDGLSQRYSQQCVELNRIQSGTDERDGQIRQKERDMEQLRMENQELQARLTEEISLMRSFITGQRSGVVPLGSYERSTSELEMLLKVKESEVEFLHKEISCLRKEVQTLTKENEALGERYKEVYVELSELRGRSERDINALKQHLKLTDAALEEGRLLGNSDNQ--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q27421-4", "uniprot_id": "OSP_DROME", "id": "Q27421-4", "name": "Protein outspread", "aln": "----MSTTTITTTVPAAPSKSAPPTPTTTGAAGATTNARTADCRKFTPNIFNKSKCSHCFRQREEHSAAALECNRRTSSNLAEPASRKVSKCGYLFVAPDWDFSNPLYRTKRWQRRWFVLYDDGELTYSVDDYPETIPQACVDMTKVLEVTSAVEVTGHPNSIAITAPERVTFVKGTSSEESQWWLNILAAFPKSKGRHKR----SATLPGGQVVGSLRPTSNGDLTLS----TKLGNRHSSYHKDTLTSSQSAGNLLSSLDLGPSSTKTAGSPLTTTQSALADDEEDDGVETGEDVDEDEEDE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TSVPRKSKTVSMGGQDENNRNAGNEITNRVSQPTTCLLIEDIRRDEKTIKDIANTITNLSQQQNKRWSTAVNNALNNQHHFGHHSQYQVTSRDETDFQMSSNSSSTKSQNPASERPKSLPLASNSTP--------------------------------------------------------------------------------------------------------------AIVSAIVKKIPTVMEQGDKTKPTARLQLHLKSPKHYQHERGDPDGGCNLDELCVNYMAKTDELRSVGKANSKSSSGQGKPPVKEESLNAKKGWLMKQDNRTCEWSKHWFTLSGAALFYYRDPLCEERGVLDGVLDVNSLTSVIPEPAASKQHAFQLTTWDKQRLVLASLSPSSRNSWLAVLRSAAGLPQLDTPPKQTDIEQDFIKAQLQQPSSSPVTPGTPAGPHFSSDEEYRT----------------------------------------------------------------------------------------------------------------------ASEGGRRDSLDWGSPLSPSPPVLRSCLRNRSLASLHKRSRSSPPSSRRSTVDSVASDELPLLVVPEEMQPTESRELKQQCETLRAEASLREARMSELLATLQRTEQQLTARLQEQQQQLNSELTQAK-------------QSASDLMHNLGMQLTESQCQIKQLEDRLAQGIEENEGLYKRLRELQAQDHSGGAALSNLQRHKIKRMDSLSDLTTISDIDPYCLQRDSLAEEYNELR------------------------------------------------------------------------------------------------SRFEKAVNEIRAMKRELKQSQNQYDALELAQAALQQKLERRQHEDGAQLQLMAARIQDLTLKYSSSERQVRALKQKLAKSERRRSLSLKGKEQLELKLSELQRETVERKEGTPPESSSSESSSQSP--------------------------------------------------------------------------------------------------------------LNAHLLQRLHSLEHVLLGSKE-----------RLEQSLTQLQQIRAGQRTRRSVSPMNDRKDGLRQLERALAETCVMVSEQMELTC-LQDSCHKCCDLRQRVEKLSALQQQTETDLQRSEQLLEQRETDLAQALEKCASQEQEQELLLQQ--RQELSEELGRQQERCRRLEKRLELLEREHG----------KQLECLREVYHTEHANAADEQSFRKRYQTEIEQLRTLCEKGLSAMETSHKRLTMDLEQK----HKMEIERLLAEKETALAEETQATLAALDAMRKAHQS---------EVQREVARFKQEFLRQVQRGEQMRGDGAKLKEEDLGELRMEILAFSEKYSIKCVENAALEEKLHMANSKLRHFQQMQQLELRNKQFRAHLASDDPSNDVHFVQGLTSDAREDADCEDSEP-APQILGATATRTTATTTTTATATTTSAAPSETESNPDSDRETADSSRAPPEKMEQSLFVIPSHMLNSSLVPAANASDQSQRSQLYRDLDGPEDGYEPCYRPFDIFAIYQNRLSYQGLKGSSTFGKSLRKSAAQTSPASSEITTTTTAPTTDPKKPSHKQMFKTAAVINIQQQVAQEEKAQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .. : . . .. : . . .:.. . : : . : . : . . . . . . : .. : .... * . : . .. : : . : :... : . .. :. :: . . . . . . . . . : . :. : : * . . . : : ::. . .. .: :. . . .* . . .. .:* * : *:.: * : ::. : :. * . . ..: . . : * : : : : . . : : . : . . . :* * :. : . : * * : *. ** *. . ...: : :*. . . : . :.: : : : : : . . . .:*: : . . : :: :. * :: . . . :. . :**: : * *.: : :::** :: :: . .: :::: :.: : : :: * :: : :. ...: : .: ... * : : : . . .:. . ::: : .:: :. . :.* . : . * : : : :: . . : *. . : . . *:. . : : ..: : **: : . . : ", "identical_positions": 34, "similar_positions": 272, "identity": "1.42%" }, { "cls_id": "homologset.agr.RGD:1308487", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "G3V6Y3-1", "uniprot_id": "G3V6Y3_RAT", "id": "G3V6Y3-1", "name": "Kinesin-like protein", "aln": "---------------------------------------------------MEERGSPDGDPARNLEQGPEGSETP------------------------------------------------------------------------------------------IQVVLRVRPMSTVELRRGEQSALHCSG--------TRTLQVSPPGGGPDVAFRFGAVLDGARTQEDVFRACGVKRLGELALRGFSCTVFTFGQTGSGKTYTLTGPPPQAEGVPVPP-SLAGIMQRTFTWLLDRMQHLDSP-VTLRASYLEIYNEQVQDLLSQGSP-RPLPVRWSKARG-FYVEQLRLVECGSLEALMELLQMGLSRRRSSSHTLNQASSRSHALLTLHISRPTSQQVPPVDLGEPPVGGKLCFVDLAGSEKVAATGSRGQLMLEANSINRSLLALGHCISLLLDPQRKQSHIPFRDSKLTKLLADSLGGRGVTLMVACVSPSAQCLPETLSTLRYASRAQRITTRPQGPKSPAVKPPQQVEAELLQLQEENRCLRLQLDQMYTKAPRVHGARVAWAQRNLYGMLQEFMLENEKLRKEMRQLRSSRDLAQAEQHVLAQQIHELERRLLLACSLPQQTS--ATVCPCRMTPAASCHVLPPL--CYCYHLCPLCRVSLTHWACPWRECHAPQQVLEPEAPGHISPSVRPPPWAPPTSPGSAKP-PQERNHSDWTQTRVLAEMLMGEEVVPSAPPLPAGPSNMPQVLRGGSGIPNQTPRLETLTHQINSSLNPSQRQPQPSEDTQSPGQGLSSY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D2Z8-1", "uniprot_id": "KIF12_MOUSE", "id": "Q9D2Z8-1", "name": "Kinesin-like protein KIF12", "aln": "---------------------------------------------------MEERGSPDGDPARNLEQGPEGSETP------------------------------------------------------------------------------------------IQVVLRVRPMSTVELRRGEQSALHCSG--------TRTLQVSP-----DVAFRFGAVLDGARTQEDVFRACGVKRLGELALRGFSCTVFTFGQTGSGKTYTLTGPPPQGEGVPVPP-SLAGIMQRTFTWLLDRVQHLDSP-VTLRASYLEIYNEQVWDLLSLGSP-RPLPVRWTKARG-FYVEQLRVVEFGSLEALMELLQMGLSRRRSSSHTLNQASSRSHALLTLHISRPTSQQVPPVDLGEPPVGGKLCFVDLAGSEKVAATGSQGQLMLEANSINRSLLALGHCISLLLDPQRKQNHIPFRDSKLTKLLADSLGGRGVTLMVACVSPSAQCLPETLSTLRYASRAQRITTRPQGPKSPGVKPPQQVENELLRLQEENRHLRFQLDQMHTTAPGAHGARMAWAQRNLYGMLQEFMLENERLRKEMRQLRSSRDLARAEQRVLAQQVHDLERRLLSACPLPQQGS--TPVCPCRMVPAASCHALPPL--CYCHHFCPLCRVPLAHWTCPRRECHMP-QVLEPEAPGHISQSVWPPPWAPPPSPGSAKP-PRERSQSDWTQTRVLAEMLMGEEVVPSAPPLSAGPSNMPYGLRGGSGIPNLTPRLETLTQQINSSLHLSQRQPQPSEDTQSPGQGLSSC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96FN5-1", "uniprot_id": "KIF12_HUMAN", "id": "Q96FN5-1", "name": "Kinesin-like protein KIF12", "aln": "---------------------------------------------------MEERGSPDGDLARSLEQGPEGPETP------------------------------------------------------------------------------------------IQVVLRVRPMSAAELRRGQQSVLHCSG--------TRTLQVSPPGGGPEVAFRFGAVLDAARTQEDVFRACGVRRLGELALRGFSCTVFTFGQTGSGKTYTLTGPPPQGEGVPVPP-SLAGIMQRTFAWLLDRVQHLGAP-VTLRASYLEIYNEQVRDLLSLGSP-RPLPVRWNKTRG-FYVEQLRVVEFGSLEALMELLQTGLSRRRNSAHTLNQASSRSHALLTLYISRQTAQQMPSVDPGEPPVGGKLCFVDLAGSEKVAATGSRGELMLEANSINRSLLALGHCISLLLDPQRKQSHIPFRDSKLTKLLADSLGGRGVTLMVACVSPSAQCLPETLSTLRYASRAQRVTTRPQAPKSPVAKQPQRLETEMLQLQEENRRLQFQLDQMDCKASGLSGARVAWAQRNLYGMLQEFMLENERLRKEKSQLQNSRDLAQNEQRILAQQVHALERRLLSACYHHQQGPGLTPPCPCLMAPAPPCHALPPLYSCPCCHICPLCRVPLAHWACLPGEHHLP-QVLDPEASGGRPPSARPPPWAPPCSPGSAKC-PRERSHSDWTQTRVLAEMLTEEEVVPSAPPLPVRPPKTSPGLRGGAGVPNLAQRLEALRDQIGSSLRRGRSQPPCSEGARSPGQVLPPH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A126GUN8-1", "uniprot_id": "A0A126GUN8_DROME", "id": "A0A126GUN8-1", "name": "Kinesin-like protein", "aln": "MSTVPCPRDILVLSKQSTPYPAFAHSVASTQVTMVRRASSVPHLNSSGGSSADSAGTSGSRRGRAPVAGSRGRKTPSTTSTGQSQRQSSGSSSSMPRSRSLTNGMRRLSPQKGTGSSGGTGGGGGSSRNTPYFLRSRENEIGSADTLEIVASKSTGSEECSTPEDNINVVVRVRPLNDKEKRDRHGSTLQFPGNGQVILEGNDVGQKRSHNRDSVRVFTYNVVFEPGATQEDILDYSGIKRIIEMGIEGFSCTAFCYGQTGSGKTHTLTGPPDLFVGKPNPKDPRHGLIFRSFLYLFQLIKNRKDVNYVLKASFMEIYNERVIDLLNPGSARKPLAVRWSKKSGGFFVENLFTVDCEELDDLLAVLEEGMRNRAVGSHAMNDHSSRSHTILTVHILSDQQTDGG----VFLSKHGKINFVDLAGSELTKKTMSEGKTLEEANNINKSLMVLGYCISSLSDSKKRTGHIPYRDSQLTKLLADSLAGNGVTLMIACVSPAHYNHAETLNTLRYASRAKRIRTKPVIKMDPREALILSLKRDIHALQMENDHLKAALNLHHQAAPNGG------PVENLLELQLDRVSSGGGVPVPKVDLQRLPELDGSELAELVKLYMVENESLRQEN----------------------------------NHLFTVRETILRDQEIVCRENERLLKKLEDVNKVCVRSPLIPARPAISPTTGKETPGTEIWTNPEPLQSPPGPDLPIEQRMSENANRRTDTAQKRIDQKRIAKNILIMANAFRKPDSDITKELNLNPEEAHAKQSTEFMPDMLT--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. *:... .* *..* :** *:**:****:. * * . *.*: .* . . * . .* :..*:: . ****:: .*::*: *:.:.*****.* :********:****** * * * . *:: *:* :*:: ::: .*:**::*****:* ***. **. :**.***.* * *:**:* *: .*: *: :*: *: .* .:*::*: *****::**::* : . **: ******** . * *.*: : ***.**:**:.**:*** * *.::: .***:***:*********.*.*****:*****: .***.********:*: *:* .* :: :: ** ** *: *: *. . .** : : : .. : :*: :* * *.: :. * *: .: .. * . * . : *: . *. * . :.*. . .. .:.: *: .:: :.: .* . . : * . .: : :. :* ..*. . :. .:.:. : *. ", "identical_positions": 191, "similar_positions": 184, "identity": "23.7%" }, { "cls_id": "homologset.agr.RGD:1308488", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q148W0-1", "uniprot_id": "AT8B1_MOUSE", "id": "Q148W0-1", "name": "Phospholipid-transporting ATPase IC", "aln": "------------------------------MSTER--DSETTFDEESQPNDEVVPYSDDETEDELEDQGSTVEPEQNRVNR-------EAEKKRETFRKDCTWQ--------------------------------------------VKANDRKFHEQ------------PHFMNTKFFCIKES----------------------KYASNAIKTYKYNGFTFLPMNLFEQFKRAANFYFLILLILQAIPQISTLAWYTTLVPLLLVLGITAIKDLVDDVARHKMDKEINNRTCEVIK------------------------------------------------------------------------------------------------------------DGRFKIIKWKDIQVGDVIRLKKNDFIPADILLLSSSEPNSLCYVETAELDGETNLKFKMALEITDQYLQIEDNLATFDGFIECEEPNNRLDKFTGTLFWK------NQSFPLDADKILLRGCVIRNTDVCHGLVIFAGADTKIMKNSGKTRFKRTKIDYLMNYMVYTIFIVLILVSAGLAIGHAYWEAQVGNY-----SWYLYDGENATPS---YRGFLNFWGYIIVLNTMVPISLYVSVEVIRLGQSHFINWDLQMYYAEKDTPAKARTTTLNEQLGQIHYIFSDKTGTLTQNIMTFKKCCINGTIYG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------DHRDASQHSHSK----------------------------------------------------------------IELVDFSWN-TFADGKLAFYDHYLIEQIQ----SGKEPEVRQFFFLLSICHTVMVDRIDG---QINYQAASPDEGALVNAARNFGFAFLARTQNTITVSELGSERTYNVLAILDFNSDRKRMSIIVRTPEG------SIRLYCKGADTVIYERLHR-----MNPTKQETQDALDIFASETLRTLCLCYKEIEEKEFTEWNNKFMAASVASSNRDEALDKVYEEIEKDLILLGATAIEDKLQDGVPETISKLAKADIKIWVLTGDKKETAENIGFACELLTEDTTICYGEDIN--SLLHTRMENQRNRGGVSAKFAPPVYEPFFPPGENR---ALIITGSWLNEILLEKKTKRS-------KILKLKFPRTEEERRMRSQ---SRRRLEEKK--------------------------------EQRQKNFVDLACECSAVICCRVTPKQKAMVVDLVKRYKKAITLAIGDGANDVNMIKTAHIGVGISGQEGMQAVMSSDYSFAQFRYLQRLLLVHGRWSYIRMCKFLRYFFYKNFAFTLVHFWYSFFNGYSAQTAYEDWFITLYNVLYSSLPVLLMGLLDQDVSDKLSLRFPGLYVVGQRDLLFNYKRFFVSLLHGVLTSMVLFFIPLGAYLQ--TVGQDGEAPSDYQSFAVTVASALVITVNFQIGLDTSYWTFVNAFSIFGSIALYFGIMFDFHSAGIHVLFPSAFQFTGTASNALRQPYIWLTIILTVAVCLLPVVAIRFLSMTIWPSESDKIQ-KHRKRLKAEEQ------WKRRQSVFRRGVSSRRSAYAFSHQRGYADLISSGRSIRKKRSPLDAIIADG------TAEYRRTVES---------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4AA47-1", "uniprot_id": "AT8B1_RAT", "id": "D4AA47-1", "name": "Phospholipid-transporting ATPase IC", "aln": "------------------------------MNTER--DSETTFDEDSQPNDEVVPYSDDETEDELEDQGPAVEPEQNRVNR-------EVEKKKETFRKDCTWQ--------------------------------------------VKANDRKFHEQ------------PHFMNTKFFCIKES----------------------KYASNAIKTYKYNALTFLPMNLFEQFKRAANFYFLILLILQAIPQISTLAWYTTLVPLLLVLGITAIKDLVDDVARHKMDKEINNRTCEVIK------------------------------------------------------------------------------------------------------------DGRFKIIKWKDIQVGDVIRLKKNDFIPADILLLSSSEPNSLCYVETAELDGETNLKFKMALEITDQYLQIEDNLATFDGFIECEEPNNRLDKFTGTLFWR------NQSFPLDADKILLRGCVIRNTDVCHGLVIFAGADTKIMKNSGKTRFKRTKIDYLMNYMVYTIIIVLILVSAGLAIGHAYWEAQIGNY-----SWYLYDGENATPS---YRGFLNFWGYIIVLNTMVPISLYVSVEVIRLGQSHFINWDLQMYYAEKDTPAKSRTTTLNEQLGQIHYIFSDKTGTLTQNIMTFKKCCINGTIYG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------DHRDASQHSHSK----------------------------------------------------------------IELVDFSWN-EFADGKLAFYDHYLIEQIQ----SGKEPEVRQFFFLLSICHTVMVDRIDG---QINYQAASPDEGALVNAARNFGFAFLARTQNTITVSELGTERTYSVLAILDFNSDRKRMSIIVRTPEG------SIRLYCKGADTVIYERLHR-----MNPMKQETQDALDIFASETLRTLCLCYKEIEEKEFAEWNKKFMAASVASSNRDEALDKVYEEIERDLILLGATAIEDKLQDGVPETISKLAKADIKIWVLTGDKKETAENIGFACELLTEDTTICYGEDIN--SLLHTRMENQRNRGGVSAKFAPPAYEPFFPPGENR---ALIITGSWLNEILLEKKTKRS-------KILKLKFPRTEEERRMRSQ---SRRRLEEKK--------------------------------EQRQKNFVDLACECSAVICCRVTPKQKAMVVDLVKRYKKAITLAIGDGANDVNMIKTAHIGVGISGQEGMQAVMSSDYSFAQFRYLQRLLLVHGRWSYIRMCKFLRYFFYKNFAFTLVHFWYSFFNGYSAQTAYEDWFITLYNVLYSSLPVLLMGLLDQDVSDKLSLRFPGLYVVGQRDLLFNYKKFFVSLLHGVLTSMVLFFIPFGAYLQ--TVGQDGEAPSDYQSFAVTMASALVITVNFQIGLDTSYWTFVNAFSIFGSIALYFGIMFDFHSAGIHVLFPSAFQFTGTASNALRQPYIWLTIILTVAVCLLPVVAIRFLSMTIWPSESDKIQ-KHRKRLKAEEQ------WKRRQSVFRRGASSRRSAYAFSHQRGYADLISSGRSIRKKRSPLDAIIADG------TAEYRRTVES---------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O43520-1", "uniprot_id": "AT8B1_HUMAN", "id": "O43520-1", "name": "Phospholipid-transporting ATPase IC", "aln": "------------------------------MSTER--DSETTFDEDSQPNDEVVPYSDDETEDELDDQGSAVEPEQNRVNR-------EAEENREPFRKECTWQ--------------------------------------------VKANDRKYHEQ------------PHFMNTKFLCIKES----------------------KYANNAIKTYKYNAFTFIPMNLFEQFKRAANLYFLALLILQAVPQISTLAWYTTLVPLLVVLGVTAIKDLVDDVARHKMDKEINNRTCEVIK------------------------------------------------------------------------------------------------------------DGRFKVAKWKEIQVGDVIRLKKNDFVPADILLLSSSEPNSLCYVETAELDGETNLKFKMSLEITDQYLQREDTLATFDGFIECEEPNNRLDKFTGTLFWR------NTSFPLDADKILLRGCVIRNTDFCHGLVIFAGADTKIMKNSGKTRFKRTKIDYLMNYMVYTIFVVLILLSAGLAIGHAYWEAQVGNS-----SWYLYDGEDDTPS---YRGFLIFWGYIIVLNTMVPISLYVSVEVIRLGQSHFINWDLQMYYAEKDTPAKARTTTLNEQLGQIHYIFSDKTGTLTQNIMTFKKCCINGQIYG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------DHRDASQHNHNK----------------------------------------------------------------IEQVDFSWN-TYADGKLAFYDHYLIEQIQ----SGKEPEVRQFFFLLAVCHTVMVDRTDG---QLNYQAASPDEGALVNAARNFGFAFLARTQNTITISELGTERTYNVLAILDFNSDRKRMSIIVRTPEG------NIKLYCKGADTVIYERLHR-----MNPTKQETQDALDIFANETLRTLCLCYKEIEEKEFTEWNKKFMAASVASTNRDEALDKVYEEIEKDLILLGATAIEDKLQDGVPETISKLAKADIKIWVLTGDKKETAENIGFACELLTEDTTICYGEDIN--SLLHARMENQRNRGGVYAKFAPPVQESFFPPGGNR---ALIITGSWLNEILLEKKTKRN-------KILKLKFPRTEEERRMRTQ---SKRRLEAKK--------------------------------EQRQKNFVDLACECSAVICCRVTPKQKAMVVDLVKRYKKAITLAIGDGANDVNMIKTAHIGVGISGQEGMQAVMSSDYSFAQFRYLQRLLLVHGRWSYIRMCKFLRYFFYKNFAFTLVHFWYSFFNGYSAQTAYEDWFITLYNVLYTSLPVLLMGLLDQDVSDKLSLRFPGLYIVGQRDLLFNYKRFFVSLLHGVLTSMILFFIPLGAYLQ--TVGQDGEAPSDYQSFAVTIASALVITVNFQIGLDTSYWTFVNAFSIFGSIALYFGIMFDFHSAGIHVLFPSAFQFTGTASNALRQPYIWLTIILAVAVCLLPVVAIRFLSMTIWPSESDKIQ-KHRKRLKAEEQ------WQRRQQVFRRGVSTRRSAYAFSHQRGYADLISSGRSIRKKRSPLDAIVADG------TAEYRRTGDS---------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FFK0-1", "uniprot_id": "E7FFK0_DANRE", "id": "E7FFK0-1", "name": "Phospholipid-transporting ATPase", "aln": "------------------------------MNSRSRADSQGSLDE---PDDEVMPYSDDETDAELED-----ELDQSVDQL-------PEPETRPAPAVEAGWS--------------------------------------------VRANDREYCKR------------PEFQKKVFLCIKKS----------------------RYSGNAIKTYKYNVLTFLPLNLYEQFKRAANLYFLCLLVLQIIPQISTLPWYTTLVPLVLVLGITAIKDLVDDLARHRMDKEINNRKCDVLL------------------------------------------------------------------------------------------------------------NGRFVETRWMNLQVGDVVRLHKNDFIPADIMLLSTSNPNSLCYVETAELDGETNLKFKMGLKVTDERLQEEQQLSQFNALVMCEEPNNRLDKFVGTMIWE------SQSYALDLDNMLLRGCKVRNTDICHGLVIFAGNDTKIMRNGGKTRFKRTRIDKLMNYMVYTIFVLLVLLCAGLAIGHTYWYESIGSK-----AWYLIDGLDYTSS---YRGFLSFWGYIIILNTMVPISLYVSVEVIRLGQSKFINWDLQMYYADKDTPAKSRTTTLNEQLGQIEYIFSDKTGTLTQNIMAFKKCTISGRTYG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------EPTTADGVSLDR----------------------------------------------------------------GKPVDFSWN-KYADRKFQFEDHFLISCIR----SKKDPQVLEFFKLLSLCHTVMVEEKEG---ELVYQAASPDEGALVTAARNFGFVFLSRTQDTITIQEMDKPQTYTMLALLDFNSDRKRMSIILKFPDG------RIRLYCKGADTVIYQRLSP-----QSKNKENTQEALDIFANETLRTLCLCYKDISQEEFDRWSRKHQTAAVSMVDRERELDEVYEEIEKDLLLIGATAIEDKLQDGVPETIAKLAKADIKIWVLTGDKKETAENIGYSCQLLTDDMKIHYGEDVN--VQLRNRQTQRRTDPQSRNKKQ---KESFFNEPGKN---ALIITGGWLNEILYEKKKKRRR-----LRLKKLRLRQNNQQSSSSTAPDSSQPVDDWEK--------------------------------EKRQEDFVDMACECSAVICCRVTPKQKANVVSLVKKYKKAVTLSIGDGANDVNMIKTADIGVGISGQEGMQAVMSSDYAFAQFCFLQRLLLVHGRWSYIRMCKFLRYFFYKNFAFTLVHFWFSFFNGFSAQTAYEDWFITLYNVCYSSLPVLLVGLLDQDVNDKLSLRFPKLYLPGQQGALFNYRNFFISLFHGIFTSLMIFFIPYGAFLQ--TMGQDGEAPSDYQSFAVVAASSLIITVNLQISLNTSYWTFVNFFAVLGSIALYFGIMFDIHSAGIHVIFPNTFTFTGAASNALRQPYLWLTIILTVGVCLLPVICIQFLYQTIYPSVGDKVQ-RNRKKYELEDEE---DERKKRKPTFQRGGRSRRSAYAFSHSRGYADLIASGRSIRQ-RPRVRPELRDS------IREVPHAENI---------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VGD4-1", "uniprot_id": "Q9VGD4_DROME", "id": "Q9VGD4-1", "name": "Phospholipid-transporting ATPase", "aln": "MIGGRRCSEAARRLRRRPDTLELSVLGGQPIETELQEDNERTPTKGAGNVDEPGIEAPEASCSAPSKRTRWFQFARSSKNRRKRLHCNEDEDVKQPERRNSDLEGSPRACLAQPEGMNIGSSTQTIATPLMIGDSFYSLAPGGGNPPPNKSDDQELYKQRDPSVTSESKSVPSLRRLSQIRRRRSSYYFSENERRIRANDKEFNAQFKYHNNYIKTSKYSLFTFLPFNLLEQFQRLANFYFLCLLVLQLIPAISSLTPVTTAIPLIGVLTLTAVKDAYDDIQRHISDSQVNNRKSKTLR------------------------------------------------------------------------------------------------------------NGKLVEAKWSEVQVGDVIRLDNNQFVAADTLLLSTSEPNGLCFIETAELDGETNLKAKQCLTETIELGDRHDSLWNFNGEIICERPNNLLNKFDGTLIWR------GQRFALDNEKILLRGCVLRNTQWCYGVVVFAGVDTKLMQNSGKTQFKSTGVDRLLNFIIIGIVLFLVSICALFAIGCAIWEGLIGQHFQLYLPWEHIIPKDYIPTGATVIGLLVFFSYAIVLNTVVPISLYVSVEVIRFVQSFLINWDEEMYYPTTNTYAKARTTTLNEELGQIQYIFSDKTGTLTQNIMTFNKCSINGRSYGDVIDLRTGELVEITEQQTIFQNSNTNNRPSPLSGAIVAPPAAPPPIILVHKAEVHAKKTSMVVTSSGEAQVLPDRPRSDIERSAPPMDASEKRPGLKHVRYSAPSRSQDADAGRLSPRLDGSGGLSPPVGNEERRISGGFKRSGAGCMQRQLSRTSSCDKVKILHDSQQTETHNMHHSSHNRKRLVKIRFKKAPSTATLGVVISQLEHHLDEEPQSTSTLSTTKHHHHRSKAFATNWSSSPHRVHALQSVDFSAN-PHHESDFRWYDRTLLDAVR----SDEE-HSHVFFRLLALCHTVMAETVDG---KLEYQAQSPDEAALVSAARNFGFVFRTRTPNSITIEVMGQTEEYELLNILDFNNVRKRMSVILRRGD-------SMVLYCKGADNVIYDRLHGG----QEDLKARTQDHLNKFAGEGLRTLALAERRLTEQYYNDWRSRQQEAALSMDSREQKLNAIYEEIESEMQLVGVTAIEDKLQDGVPKSIANLQNAGIKIWVLTGDKQETAINIGYSCQLLTDELADVFIVDGNSVEEVEKQLRQFKESIKIYNRFRPGGFDPFDRLNSDSNMDPLSVTMTQTSAFMQETNLPPTPPPPPAISVVTFRWDEKNKDNKGGPDSAECNNLFGDEKGSEDGGTASIVVDENTGFALVVNGHSLVHCLSPELENKFLDIASQCKAVICCRVTPLQKALVVELIKRAKNAVTLAIGDGANDVSMIKAAHIGVGISGQEGLQAVLSSDYSIAQFRYLERLLLVHGRWSYYRMCKFLRYFFYKNFAFTLCHCWYSLFCGFSAQTVFDPMFISVYNLFYTSLPVLALGVFEQDVSDKNSLEFPRLYTPGLKSELFNIREFIYSVLHGAFTSLVLFLIPYGVYKD--GVSANGFVVSDHMTLGAVVATILIVDNTAQISLYTSYWTVVNHVTIWGSLVWYFVLDYFYN-------YVIGGPYVGSLTQAMKDLTFWVTMLITVMALVAPVLAYKFYLLDVHPSLSDKIRQKSLKKIHSRASS-----DVRRTASSRRGRRSVRSGYAFAHQEGFGRLITSGKIMHKLPQDFAFPLGLG------TKKTQVLHNNLNSADGPNSKGNNVTGHHMVNNNTNMRHNQNQNHSSMADITADGRGNGGDDGRGSGGSDDMSPRAPCQDLDTINL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32660-1", "uniprot_id": "ATC5_YEAST", "id": "P32660-1", "name": "Phospholipid-transporting ATPase DNF1", "aln": "-MSGTFHGDGHAPMSPFEDTFQFE----DNSSNEDTHIAPTHFDDGATSNKYSRPQVSFNDETPKNKREDAEEFTFNDDTEYDNHSFQPTPKLNNGSGTFDDVELDNDSGEPHTNYDGMKRFRMG------------TKRNKKGNPIMGRSKTLKWARKNIPN-PFEDFTKDDIDPGAINRAQELRTVYYNMPLPKDMIDEEGNPIMQYPRNKIRTTKYTPLTFLPKNILFQFHNFANVYFLVLIILGAFQIFGVTNPGLSAVPLVVIVIITAIKDAIEDSRRTVLDLEVNNTKTHILEGVENENVSTDNISLWRRFKKANSRLLFKFIQYCKEHLTEEGKKKRMQRKRHELRVQKTVGTSGPRSSLDSIDSYRVSADYGRPSLDYDNLEQGAGEANIVDRSLPPRTDCKFAKNYWKGVKVGDIVRIHNNDEIPADIILLSTSDTDGACYVETKNLDGETNLKVRQSLKCTNTIR-TSKDIARTKFWIESEGPHSNLYTYQGNMKWRNLADGEIRNEPITINNVLLRGCTLRNTKWAMGVVMFTGGDTKIMLNSGITPTKKSRISRELNFSVVINFVLLFILCFVSGIANGVYYDKKGRS-------RFSYEFGTIAGSAATNGFVSFWVAVILYQSLVPISLYISVEIIKTAQAAFIYGDVLLYNAKLDYPCTPKSWNISDDLGQVEYIFSDKTGTLTQNVMEFKKCTINGVSYG-----------------------------------------------------------------------------------------------------------------------------------------------------RAYTEALAGLRKRQGIDVETEGRREKAEIAKDRD------------------------------------------------------------TMIDELRALSGNSQFYPEEVTFVSKEFVRDLKGASGEVQQRCCEHFMLALALCHSVLVEANPDNPKKLDLKAQSPDEAALVATARDVGFSFVGKTKKGLIIEMQGIQKEFEILNILEFNSSRKRMSCIVKIPGLNPGDEPRALLICKGADSIIYSRLSRQSGSNSEAILEKTALHLEQYATEGLRTLCIAQRELSWSEYEKWNEKYDIAAASLANREDELEVVADSIERELILLGGTAIEDRLQDGVPDCIELLAEAGIKLWVLTGDKVETAINIGFSCNLLNNEMELLVIKTTG-----DDVKEFGSEPSEIVDALLSKYLKEYFNLTGSE------------EEIFEAKKDHEFP-------KGNYAIVIDGDALKLALYG-------------------------------------------EDIRRKFLLLCKNCRAVLCCRVSPSQKAAVVKLVKDSLDVMTLAIGDGSNDVAMIQSADVGIGIAGEEGRQAVMCSDYAIGQFRYLARLVLVHGRWSYKRLAEMIPEFFYKNMIFALALFWYGIYNDFDGSYLYEYTYMMFYNLAFTSLPVIFLGILDQDVNDTISLVVPQLYRVGILRKEWNQRKFLWYMLDGLYQSIICFFFPYLVYHKNMIVTSNGLGLDHRYFVGVYVTTIAVISCNTYVLLHQYRWDWFSGLFIALSCLVVFAWTGIWSS------AIASREFFKAAARIYGAPSFWAVFFVAVLFCLLPRFTYDSFQKFFYPTDVEIVREMWQHGHFDHYPPGYDPTDPNRPKVTKAGQHGEKIIEGIALSDNLGGSNYSRDSVVTEEIPMTFMHGEDGSPSGYQKQETWMTSPKETQDLLQSPQFQQAQTFGRGPSTNVRSSLDRTREQMIATNQLDNRYSVERARTSLDLPGVTNAASLIGTQQNN-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ... . . .. : . . . . ::. : .: : :. :* * *:* **. :**:* *: **:. **.*** *::* . :. : :**: :: :**:** :* * * ::** . . : : :: * ::***::*:.:*: :.** :***:*:.:. *::** :******** : * * . : . : .* *:. * .: *.: *. .: :::***** :***. . *:*:*:* ***:* *.* * * : :. :*: : .:.*. :. .*. : * . . *:: *: *: :::******:***:*: *: :* * :* . : ...:: .:.::***:.*************:* *:** *.* ** .: : :* * . .. : .: :: :: . :: *: *::**:*:.: . :: :* ****.*** :**:.** * :* . : :. . . : :* :*:**. ***** *:: * *****.:**.** . .* *: :* * ****.:. : : . : * : *: : .*: *: : :.** :: *:* *****:******. * * :*.**:******* *** ***::*:**.:: . . : . . :: .: . . . ...*: :. :* **:****:* *** **.*:* ..:**:****:*** **::*.:*:**:*:** ***:.***::.** :* **:******** *:.::: *****: *:* *:.:: .:... :: :: .**: ::****: :*:::***.*. ** .* ** * :* :.*: ::.* *:: *::* .: . : :* .. ... :: :: . : * * .. . : * * : : :. :* .::::* : * . . *: : :: : . .* : * : .:: . . . * : . . : . ", "identical_positions": 311, "similar_positions": 364, "identity": "16.54%" }, { "cls_id": "homologset.agr.RGD:1308489", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L1E9-1", "uniprot_id": "A0ABK0L1E9_RAT", "id": "A0ABK0L1E9-1", "name": "", "aln": "MIEDKGPRVTDYFVVAGLTDTSTLLDQEINRIDTNK-SIGPKAPITDIAVIIKSAGETVPEGYTCVEATPSALQANLNYGSLKSPELFLCYRRGRDKPPLTDIGVLYEGKERLIPGCEVIQATPYGRCANVNNSSTTSQRIFITYRRAPPVRSQNSLAVTDICVIITSKGETPPHTFCKVDKNLNCGMWGSNVFLCYKKSVPASNAIAYKAGLIFRYPEEDYESFPLSES--VPLFCLPMGATIECWDPQTKYP-----LPVFSTFVLTGSS-AEKVYGAAIQFYEPYSRDLLTEKQLSQLGLLTPVERKVVS-KPINSNKCICLLSHWPFFEAFKKFLMFIYKVSVSGP-HPLPIEKHISHFMQNIPFPSPQRPRILVQLSVHDALILSQPVSTPLPLSGANFSSLLMNLGPENCATLLLLVLLESKILLHSLRPAVLTGVAEAVVAMIFPFQWQCPYIPLCPLSLAGVLSAPLPFIVGVDSRYFDLHDPPQDVVCIDLDTNTLYVADEKKNTNWKQLPKKPCKSLLGTLRKLYLQLCSVHRKPQESSAIEMTPIEADFSWQKKMTQLEMEIQETFLRFMASVLKGYRSYLRPITEAPSNKATAADSLFDRQGFLKSRDRAYTKFYTLLSKTQIFIRFIEECSFVSDKDTGLAFFDDCIEKLFP-DKGVEKTDKVDLDSAEDTKLIELDDSQKSEHTVFITPPEPPPDDGSDLSP-----QYSYTYFPRLDLKLFDSPQEPKLRFSRHPPGSGITNSPALMAKRTKQEIKTAHKLAKRCYTNPPQWAKYLFSHCYSLWFICLPAYVRVSHPK---VRALQQAHDVLVKMRKTDVDPLDEVCYRVVMQLCGLWVHPVLAVRVLFEMKTARIKPNAITYGYYNKVVLESPWP-SSTRSGIFLWTKVRNVVHGLAQFRQPLKKTGQKS--QVFSISAPQNAACGSDGDTVSHGSVDSSNDANNGEHTVFVKDLISLDSIDNHSSTGGQSDQGYGSKDELVKEDADIHASEEHMPQELTA-TELHIEEESDLSTIVPKHSQPTPEPQSPTEPPAWGSSIVK----VPSGLFDTNNRTSSTGSSSNALFSTQAP-------VEDAVFGEATNFKKSGDRGEKRQKHFPERSCSFSSESRAGMLLKKSSLDLNSSEMAIMMGADAKILTAALTCPKTSPLHVARTHSFENVNCHLADNRTRVSEGIWDSEHRSSPVLEMLEESQELLEPVVGDTVAETAVEMSFNNVQSNSNSNQSRDTKAGSQDTVNKRSSSYTTGKAIEREDVETGLDPLSLLATECV-EKTSDSED--KLFSPVISRNLADEIESYMNLKSPLGSKSSSMELHGEGNQEPG---SPALFTHPLERRSSLPS-----AQDSTEIEKSPPAVSRSKTLTGRFKPQTPYRTYKDRSTSLSALVRSSPNSSLGSVVN-SLSGLKLDNILSGPKIDVLKSSMKQAATVASKMWVAVASAYSYSDDEEEPNK-DYSFPAGLEDHHILGESLSPTTSISGLVP----SELTQSSTSLGSSSSSGDVGKSQCPTGEVPFSRNIKGQDFEKSDHGSSQNTSMSSIYQNCAMEVLMSSCSQCRACGALVYDEEIMAGWTADDSNLNTTCPFCKSNFLPLLNVEFKDLRGSASFFLKPSTSGDSLQSGSIPSANEPLEHKPVSSSAEP-DLISFMDYSKHSETITEEASYTVESSDEIKKTS-DVQSVKMSSVPNSLSKRNVSLTRSHSVGGPLQNIDVSQRPFHGISTVSLPNSLQEDVDHLG-KRPNPPPVSVPYLSPLVLRKELESLLENEGDQVIHTSSFINQHPIIFWNLVWYFRRLDLPSNLPGLILTSEHCNEGVQLPLSSLSQDSKLVYIQLLWDNINLHQEP-GEPLYVSWRN--LNSEKKLSLLSEEQQAASALVETIRQSIQQNDVLKPINLLSQQMK----PDTKRQRSLYREILFLSLVSLGRENIDIEAFDNEYGLAYRSLSS-EILEKLQKIDAPPSISVEWCRKCFGAPLI-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A6H8H2-1", "uniprot_id": "DEN4C_MOUSE", "id": "A6H8H2-1", "name": "DENN domain-containing protein 4C", "aln": "MIEDKGPRVTDYFVVAGLTDTSTLLDQEINRTDTN--SIGPKAPITDIAVIIKSAGETVPEGYTCVEATPSALQANLNYGSLKSPELFLCYRRGRDKPPLTDIGVLYEGKERLMPGCEVIQATPYGRCANVNNSSTTSQRIFITYRRAPPVRSQNSLAVTDICVIITSKGETPPHTFCKVDKNLNCGMWGSNVFLCYKKSVPASNAIAYKAGLIFRYPEEDYESFPLSPS--VPLFCLPMGATIECWDPQIKYP-----LPVFSTFVLTGSS-AEKVYGAAIQFYEPYSQERLTEKQLTQLGLLTLVEKRVVS-KPINSNKCICLLSHWPFFEAFKNFLMFIYKVSVSGP-HPLPIEKHISHFMQNIPFPSPQRPRILIQLSVHDAFILSQPVSTPLPLSGANFSSLLMNLGPENCATLLLLVLLESKILLHSLRPAVLTGVAEAVVAMIFPFQWQCPYIPLCPLSLAGVLSAPLPFIVGVDSRYFDLHDPPQDVVCIDLDTNTLYVADERKNINWKQLPKRPCKSLLGTLRRLYQQLCSVHRKPQESSAIEMTPIEADYSWQKKMTQLEMEIQETFLRFMASILKGYRSYLRPITEAPSNKATAADSLFDRQGFLKSRDRAYTKFYTLLSKTQIFIRFIEECSFVSDKDTGLAFFDDCIEKLFP-DKGVERTEKVDLDSAEDTRLIELDDSQRSEHTVFIMPPEPPPDDGNNLSP-----QYSYTYFPRLDLKLFDSPQKLKLCFNRHPPGSSITNSPALMAKRTKQEIKTAHKLAKRCYTNPPQWAKYLFSHCYSLWFICLPAYVRVSHPK---VRALQQAHDVLVKMRKTDVDPLDEVCYRVVMQLCGLWVNPVLAVRVLFEMKTARIKPNAITYGYYNKVVLESPWP-SSTRSGIFLWTKVRNVVHGLAQFRQPLKKTGQKS--QVFSIS-------------------------------------------------GGQSDQGYGSKDELVKEGADGHAPEEHTPPELTT-TELHIEEECDISAIVSKHLQPTPEPQSPTEPPAWGSSIVK----VPSGLFDTNNRTS-TGSTSTVLFSTQAP-------VEDAVFSEVTNFKKNGDRGEKKQKHFPERSCSFSSESRAGMLLKKSSLDLNSSEMAIMMGADAKILTAALTCPKTSPPHVTRTHSFENVNCHLADSRTRMSEGTRDSEHRSSPVLEMLEESQELLEPVVGDNVAETAAEMTCNSLQSNSHSDQSRDTQAGAQDPVNKRSSSYATRKAIEREDVETGLDPLSLLATECV-EKTSDSED--KLFSPVISRNLADEIESYMNLKSPLGSKSCSMELHGEGNQEPG---SPAVFAHPLERSSSLPSDRGPPARDSTETEKSSPAVSSSKTLTGRFKPQSPYRAYKDRSTSLSALVRSSPNSSLGSVVN-SLSGLKLDNILSGPKIDVLKSSMKQAATVASKMWVAVASAYSYSDDEEETNK-DYSFPAGLEDHHIVGETLSPNTSVSGLVP----SELTQSNTSLGSSSSSGDVGKLQCPAGEVPFSRNIKGQDFEKSDHGSSQNTSMSSIYQNCAMEVLMSSCSQCRACGALVYDEEIMAGWTADDSNLNTTCPFCKSNFLPLLNVEFKDLRGSASFFLKPSTSGDSLQSGSIPSASEPSEHKPTSSSAEP-DLISFMDFSKHSETITEEASYTVESSDEIKKTNGDVQSVKMSSVPNSLSKRNVSLTRSHSVGGPLQNIDFSQRPFHGVSTVSLPSSLQEDVDHLG-KRPSPPPVSVPYLSPLVLRKELESLLENEGDQVIHTSSFINQHPIIFWNLVWYFRRLDLPSNLPGLILTSEHCNGGVQLPLSSLSQDSKLVYIQLLWDNINLHQEP-GEPLYVSWRN--LNSEKKPSLLSEQQQAASALVETIRQSIQQNDVLKPINLLSQQMK----PGTKRQRSLYREILFLSLVSLGRENIDIEAFDNEYGLAYRSLPS-ESLERLQRIDAPPSISVEWCRKCFGAPLI-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5VZ89-1", "uniprot_id": "DEN4C_HUMAN", "id": "Q5VZ89-1", "name": "DENN domain-containing protein 4C", "aln": "MIEDKGPRVTDYFVVAGLTDTSTLLDQEINRLDTK--STGPKAPITDIAIIIKSAGETVPEGYTCVEATPSALQANLNYGSLKSPELFLCYKRGRDKPPLTDIGVLYEGKERLIPGCEVILATPYGRCANVNNSSTTSQRIFITYRRAPPVRPQNSLAVTDICVIVTSKGETPPHTFCKVDKNLNCGMWGSSVFLCYKKSVPASNAIAYKAGLIFRYPEEDYESFPLSESD-VPLFCLPMGATIECWDPETKYP-----LPVFSTFVLTGSS-AKKVYGAAIQFYEPYSRELLSEKQLMHLGLLTPVERKMVS-KSINTNKCICLLSHWPFFEAFRKFLMFIYKLSVSGP-HPLPIEKHISHFMQNIPFPSPQRPRILVQLSVHDALILSQPVSTPLPLSGANFSTLLMNLGPENCATLLLFVLLESKILLHSLRPAVLTGVAEAVVAMIFPFQWQCPYIPLCPLSLAAVLSAPLPFIVGVDSRYFDLHDPPQDVVCIDLDTNMLYVSDEKKNMNWKQLPKKPCKNLLSTLKKLYPQLSSVHQKTQEGSAIDMTPIEADFSWQKKMTQLEMEIQEAFLRFMASILKGYRTYLRPITEAPSNKATAADSLFDRQGFLKSRDRAYAKFYTLLSKTQIFIRFIEECSFVSDKDTGLAFFDDCIEKLFP-DKGTEKTDKVDFDSAEDTRLIELDDSQKSEHTVFIMPPEPPPDDGKDLSP-----KYSYKYFPRLDLKLFDRPQELKLCFSRHPTGNSITKSPPLMAKRTKQEIKTAHKLAKRCYTNPPQWAKCLFSHCYSLWFICLPAYVRVSHPK---VRALQQAYDVLIKMRKTDVDPLDEVCYRVVMQLCGLWGHPVLAVRVLFEMKTARIKPNAITYGYYNKVVLESPWP-SSTRSGIFLWTKVRNVVRGLAQFRQPLKKTVQRS--QVSSIS-------------------------------------------------GGQSDQGYGSKDELIKDDAEIHVPEEQAARELITKTKMQTEEVCDASAIVAKHSQPSPEPHSPTEPPAWGSSIVK----VPSGIFDVNSRKSSTGSISNVLFSTQDP-------VEDAVFGEATNLKKNGDRGEKRQKHFPERSCSFSSESRAGMLLKKSSLDSNSSEMAIMMGADAKILTAALTCPKTSLLHIARTHSFENVSCHLPDSRTCMSESTWNPEHRSSPVPEMLEESQELLEPVVDDVPKTTATVDTYESLLSDSNSNQSRDLKTVSKDLRNKRSSLYGIAKVVQREDVETGLDPLSLLATECTGGKTPDSED--KLFSPVIARNLADEIESYMNLKSPLGSKSSSMELHREENRESG---MTTAFIHALERRSSLPLDHGSPAQENPESEKSSPAVSRSKTFTGRFKQQTPSRTHKERSTSLSALVRSSPHGSLGSVVN-SLSGLKLDNILSGPKIDVLKSGMKQAATVASKMWVAVASAYSYSDDEEETNR-DYSFPAGLED-HILGENISPNTSISGLVP----SELTQSNTSLGSSSSSGDVGKLHYPTGEVPFPRGMKGQDFEKSDHGSSQNTSMSSIYQNCAMEVLMSSCSQCRACGALVYDEEIMAGWTADDSNLNTACPFCKSNFLPLLNIEFKDLRGSASFFLKPSTSGDSLQSGSIPLANESLEHKPVSSLAEP-DLINFMDFPKHNQIITEETGSAVEPSDEIKRASGDVQTMKISSVPNSLSKRNVSLTRSHSVGGPLQNIDFTQRPFHGISTVSLPNSLQEVVDPLG-KRPNPPPVSVPYLSPLVLRKELESLLENEGDQVIHTSSFINQHPIIFWNLVWYFRRLDLPSNLPGLILTSEHCNEGVQLPLSSLSQDSKLVYIQLLWDNINLHQEP-REPLYVSWRN--FNSEKKSSLLSEEQQETSTLVETIRQSIQHNNVLKPINLLSQQMK----PGMKRQRSLYREILFLSLVSLGRENIDIEAFDNEYGIAYNSLSS-EILERLQKIDAPPSASVEWCRKCFGAPLI-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BE44-1", "uniprot_id": "A0A8M2BE44_DANRE", "id": "A0A8M2BE44-1", "name": "", "aln": "MIEDKGHRVTDYFVVAGLTDKSTPLEQDISEAKSS----GPKAPITDLAVINKSSGETVPEGFTCIESTYSGQPANLNHGSLKSPELFLCYKRGRGKPPLIDIGVLYEGKERLIQGCEVIEATPFGRCANVNNSSATSQRIFITYRRAPPVQPQNSLAVTDICVIITNKGETPPHTFCKVDKNLNCGMWGSSVFLCYKKSVSSSNSIAYKAGLIFRYPEEDYESFPLSES--VPLFCLPMGAKIECWAPNTRYP-----LPVFSTFVLTNSN-GEKVYGAGIQFYEPYPVDGLSEKQKIQLGLVSAVDKKVLPNRTVNTNKCICLLSRWPFFEAFRKFLMFLYKLSANGV-SPLPIEKHISHFMHNVSFPSPQRPRILVQLSAHDTLILSQPVCTPLPLSGADYSTLLMNLGPENCATLLHFVLLESKILLHSLRPAVLTGVAEAVVAMIFPFQWQCPYIPLCPLSLAGVLNAPCPFIVGVDSRYFDLYDPPPDVVCVDLDTNTIYLSDEKRHSNWKNLPKKPSKSLISFLGSLHHQLATVRRTATEGLAVEMTPIEADFTWHKKKTELEMEIQEVFLRFMASILKGYRTYLKPITQAPSEKATAADSLYDLQGFLKSRDRAHQKFYSQLTKTQIFIRFVEECTFVSDKDTGLAFFDDCIRKLFPSDKGTDKGTKVEGESSEDTRLMELDESQKSEHTVFVMPPEPPLEDGPDPPP-----KYSYKNFPSLRLELFDRPLELRPALSTRAAGSSVSSSPALLAKRTKQEIKMAYKLAKRFYSNPPQWAKCLCSHCYSLWFICLPARMRTAQSK---PRAMQQAFNVLLKMRSSEVEVLDEVCYRVVMQLCGLWEMPVMAVRVLMEMKKAGVEPNAITYGYYNKAVLESPWP-SRNRSGLFMWTKMRNLVRGVVQFKRALRGTTLQIGSSLKSTDLSASTAVGADGDRLSHGSVDG----IVEEHILFSHSILVEDVIDSHYSTAAQSDQGYGSKDELPQEHTEEPVTSPPLSTNHTCSSKETNTKNGQDIASSVDSVVAVTEPPSPAEIAPCVASIVKPSTDIPVHFDSTAGRGETAGVCTGKLFMSRKKSEDVALSVEDATVIPDSQLPQSGQ--QQRVKAFMERSCSFSAESKAGMLQKKSSLELS----ADHMGADAKILAAVFSGSQTPPPFAS-----------IAPFKEFKVEATLSPALQE----EEQEEKQETKHESFTSAAEGVEKSIKRDNAAAESNSSERVGRTTG---------SAVSSSKAVERENVEMGADPLSLFASETEDTTSIQSQESTRTFPPLVSRNLADEIEMYMSLQSPLTARSPSMELQQGSNPESINCPDSPAVKQSLERRSSLPIG-PVKVASSTEHPKPSPAVTRSKTFAVKS-PKTPG-SAGQRSSSLTALVKSSQNSSLGSVIN-SISGIKMDSLLVGPKVDMLKSGMKQAANVASKMWDAVASAYSYSDDEEDNLKPQYSFPARLEEQLLSGEGDTENTLPRGLMPSLGSNGLAHSNTSLGSSSGSSDTGQAHLSTPLTPG-RSMRGADSERSEHSSSHHASTSSIYQNCALEVLMSSCSQCRSCEALVYDEEIMAGWTADDSNLNCTCPFCQVTFLPLLHVEFQDLRATPGFYLKTSTSGDSIHSSTTQPTTSSSSEVKVSSPSDPSDLMTFAESSEDSKSPVEMP--VAQTGTPKILVPEPVHSDPLGLMERQAEKRNT-LTRSNSMGGPLQNLDLIQRPNHGISTISLPNSLQEVSDTLGQKRPNPKPVSVPYLSPLVLRKELESLLENEGDQVIYTHKFLSQHPIIFWNLVWYFRRLDLPSILPGLILTSEHCNNGVKLPQTSLSQDSKQVYVQLLWDNVNLHQEP-TEPLYQLWRT--FLQ-RKGTLAPTDHQETRSLLNSIVRSIQMNDVYGPINMLIREIKKH--PEVKRQRSVYREIMFLSLVALGRENIDIEAFNREYRLAYSQLSA-EQLKVLSPIDRPPSNGVQWCLNSFGAPVI-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W3D3-1", "uniprot_id": "CRAG_DROME", "id": "Q9W3D3-1", "name": "DENN domain-containing protein Crag", "aln": "-MEEK--RIADYFVVAGMPENPQLLQENSFNDSGRLRAATTIEPITDIGVYFPLLGEEVPEGYEILSHTPTGLQANLNHGSVRTTDCYIYFRRGKDRPPLVDIGVLYDGHERIMSDAEIVAETPGGRVANVNNS---SAKTFLTYRRARADMPCNELVVTELCVIVQSKGERAPHAFCLIYKTLNKGYVGSDVYLCYKKSMYRPKHISYKPEILLRYPTFDHTDFPLNLCPSVPLFCLPMGASLEAWPHVNGTEKRKPISPVFSTFVLTVSDGTYKVYGSALTFYEDYDESKLSAEQKELLGWDEEFG----AQHSLHMIKAICLLSHHPFGDTFDKWLKYLHRMVLYDVNIPIPVERYITQLLDEVPFPAPS-IHLQLSSESNDRILLTQPEDSPLPRSGAGFHILLQNLGTDNCLHVLLLALTEQKILIHSLRPATLTAVAEAIVSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIGVDSRFFDLYEPPTDVTCIDLDTNNISLCESQRHLSPKLLPKRAARLLRQTLTELENAKPISYDSTN--------SLDRDIRKRKRELVLEQRIQEAFLLFMASILRGYRDFLVPISKAPSVGATDPSALFQLKAFLRSRDKSHQKFFELMMKTQMFIRFIEERSFVSDGDHGLSFFDECAEKVGN-----------YDETPAQLHLVDWDTGQNSERTKYIFPPDSVTPAGSQPGGGGGGLAYNYENFT-LQPELLQSTKKTALSKFLQLQLNASLSPGSPIARRTKHEIKLSQKMASRCQQHPEAWSKYLLATCYSLYFLILPSMVLDPRHAGKEPEILRAAYDVLVRASRLKIT-CDEFCYRIMMQLCGIHNLPVLAVRLHYLMKRSGVQANALTYGFYNRCVLESQWPQDSTTISQIRWNRIKNVVLGAAQFRKAGKQRAASKVNKSLSAS----------------------------------------------------QDQNLSTLETVDGQSRTSLASSSGDGGGHGLLDFAAFDRLRNKLGSIVRQTVTGGNNETMGDAVNNTGLLIPGELSAPNTP---------------------------------------------------------------------------------------TYGGDTEILAKALQQQQPRKQIMSIGGG--------DDDDEDEDEDEYTAGSPSTPQKQLEAGADDLEYAGGGDYEADEEDEDEVDEHVAAQRARQR-----------------VQSPTKISPRTPVTQNDPLGALNEEESAASATPTQET-----QQEQQHSQSQIDSSIYSDKPILFRGQRSATFDES----------TQIGKSMHRSETMPVASSG-VTNSLANIGSSLKFTFGRYSPARLSLKKDLKLPANIIENISSISPSLTGKKSNELIQGSLSSIKSAANSLTKKFDEIKGVISANSTPTKTNNGHHPHGLHHGHHHPHHHHHHHSQHGNAEQEEHDAAVHEEGKLRR---------VSSDLDPWGRLSESRKSSYNNLVPLGENSSTGALHMHAFPAVPDNLYSLTSENAADRDCDVLIQLTTCSQCHNCSVLVYDEEIMSGWTAEDSNLNTTCHACNKLTVPFLSVQIERQVEES----------------------------------------------------------------------------------------------------------------------EQSDPLQDGKEQIANGNSHKTSLTVPYLNPLVLRKELENILTQEGDIALIKPEFVDEHPIIYWNLLWLMERIESKTHLPELCLPVPSDKEHIDP-----LSKVKTVHIQCLWDNLSLHTEASGPPMYLLYRETQPTSPLIKALLTDQAQLNKNVIQQIISAIRCNDFATPLKRLANERHKLKSNGVERSHSFYRDILFLALTAIGRSNVDLATFHREYAAVFDKLTERECNMYYRNQDLPPSASTIFCRAYFRPLLLP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*:* *::*******:.:.. *::: . . . ****:.: ** ****: :. * :. ****:**:::.: :: ::**:.:*** ******:*:**:: ..*:: ** ** ****** * : *:***** . . *.*.**::***: .*** .**:** : *.** * **.*:******: .: *:**. :::*** *: .***. . **********.:*.* ********* *. ****:.: *** * . *: :* ** . . :.:: *.*****: ** ::* ::* ::::: . *:*:*::*::::.::.**:*. :: :. . :* ::*:** :*** ***.: ** ***.:** :* :.* *.***:******.**.****:*:::***:***********.** ** ** *:::*****:***::** **.*:***** : :.:.::: . * ***:..: * * * .. .:: * :*: ** .***.** ****:*:*** :* **::*** ** ..:*:: :.**:***::: **: : ***:****:** :**** * **:***:* .*: ::. : :*:: * .*.**:* :: **:. * : *.* *. * :*:: . : : .. .. . :*:***:*** : *:*.* :* *:* * : ****:*: **: : .: . :: *.:**:: .: **.***::*****: **:***: ** : ::.**:***:**: **** ** . . . : *.:::*:* * .**::. : . * . .**. .: : : : ... . : . : : : . :: * *.*::**: .: :. : * . . : :: . :. : ..: : . :. . ***. : * .: ::: :: .:*: : ..*: :. . . :.:.* .::* . .. .. .: .: . : :. : .:::: * . ..::: *:*.:* *.* :*. :. :. :.. . . :.... . : .:* . *: . . :. .. *.. . : . . :: .. :* .: ::* : : :::****: * .********:****:***** :* *: :*:* :::: . . ...**: : :. .. .::****.*********.:* :*** .: . .*:.:****:***:* :.*:: : ** * *. : :. .. * *::* ****:.** *. *:* :* . :* . : * ::: * :*: *:. *:: * .: : :*.:*.**:*:**:*.::**.*:*: :*..** .: .*. * * *** .. :* * . :: ", "identical_positions": 489, "similar_positions": 525, "identity": "24.27%" }, { "cls_id": "homologset.agr.RGD:1308490", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M3AI27-1", "uniprot_id": "A0A8M3AI27_DANRE", "id": "A0A8M3AI27-1", "name": "", "aln": "---------------------------MCQSANAM----------------WSRWSAMLVWILLLLCCSANVVNTILYQVTEEQPPNTLIGSLASDQGLPDTGHLYKLEVGAP------YLRVDGKTGDIYTTENSIDRES--LKDCRNLFEGDPCFLEFEVSITDLMKGTGPRLIEG---RIEILDENDNTPQFSSPVLTLSIPENTHVGALFAIPVATDRDSGSNGIADYALTTG-----------------------------------------------------------------------------------------------PEATNLFSLQVAQDSDEKLPQLIVLGNLDRELRDSY----------DLNIKVVDGGSPPRQSSALLRITITDANDNVPKFERSHYEGELPENSPVGHSVLQVKANDSD-MGPNGEVTYSLHQPSSPVMRLLSIDRNTGIIFVKGSVDREEISILKFYVQAKDNGPQ-------SKSSKALVTITVKDQNDNAPSIRIRGIGLVTHEDGVANISEDMPVGTAVALVEVSDRDEGENAVVTCVVAGDVPFQLRSASETGNDRKRKYFLQTTTLLDYERIKEYRIEIVAVDSGNPALSSTNSLKVQVTDMNDNAPVFSPTLYEVEFFEENQPGDKVLDVVATDADSGTNAELTYSITGGSVPEGLFEINPNTGEVRVMSQLDRE----QLDHYQFLVAAADKGVPSLRGTATVVVKVLDRNDNDPKFMLNGYSFSVQENMPPLSPVGMVTVNDHDEGENARVQLSVEPDNG---KFMIQNGTYTILSTISFDREKESTYSFRLKAVDGGDPPRSSYVGITINVLDENDNAPYVTKPANSSYKFLDPRTSPETHVESVEAEDIDIGLNSELDFNIVGGNPHGLFRIS-SEGEITLAKEFTPKHIGLHRLVVKVKDKGTPPRQTTALVHIYVNET---------------------------------------------------IGNVSHVEGLVGHSLYTPLEMDIAGDPDYSRDP-HSNILFA---VLGGFSVVILIIVVAMIIRHLVLKENKSGYQAGKKETKDLYAPKPGPKSNKN--KKAKKSKAPKPANPSEEDEGGTLQKGLKFNLMNENVNDSPRIHLPLNYPPGSPDLGRHYRSNSPLPSIQLQPQS---------PSASKKHQAVQDLPATNTFVGTG-DNNSTGS----------DQYSDYSYKANSSKYST-KQLPHRRVTFSTANQAQDLQDPSQHSYYDSGLEESETPSSKSSSGPRIGPLALPEDH-----------YERTTPDGSIGEMEHPENDLRPLPDVAMTGKCTR--------ECTEYGHSDSCWMPGQPSPNRSKSAKSGPKLSTFVPYQEREGQERLMADSS-----------SKPHGEERSGGGSNKVASIRFLPPYTSAYSTGGDSGKD-CPREEIPLNQTADYVPATTPSSQGS--KREIYL--------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1PVC3-1", "uniprot_id": "A0A8M1PVC3_DANRE", "id": "A0A8M1PVC3-1", "name": "", "aln": "----------------------------------M----------------DLPVVLFLLWGLLLDLLTG-AVGGILYRVHEEQPPSTLIGSLAADQGLPDTGHLYKLEVGAP------YLRVDGKTGDIFTTEIPIDRET--LKDCRN--KGKPCFLEFEVSVTDLIQNQSPRLIEG---RIEVQDINDNTPQFPSPVLTLSVPENTHMGALFSIPLATDKDTERNGVADYTLTAG-----------------------------------------------------------------------------------------------PEAVALFGLQVAEDRGEKLPQLIVLGSLDRELKDSY----------DLTIKAVDGGNPPRYSSALLRVVIADANDNAPKFEKSSYEAEVAENSPIGHSVLQVKANDSD-LGPNGEIEYTLHQAIDPVPKLLRIDRSSGIIYVKGPLDREEINNLKFYVVARDKGPS-------PKSSKTYVSIDVTDQNDNAPAVEIRGIGLVTHSDGVANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVPFQLRPASDSSVDNKRKYFLQTTTPLDYERVRDYRVEIVAVDSGNPALSSTNSLKVQVTDTNDNSPIFSPTLFEVEFAEENQPGEKVVEVVASDADSGTNAELVYSIIADSSTRGLFEIDPNSGEVRARSPFDRE----HKDRYEFRVTAADKGVPSHRGTATVVIKVLDRNDNDPKFMLSGYSFSVLENMPPLSPVGMVTVQDMDEGENAQVQLSVEPDVG---KFVIQNGTGTILSSISFDREKESSYTFRLKAVDGGDPPRSSYVGVTINVLDENDNAPVVTKPSNSSFIRLSPMAAPDSVVEVVEAEDIDSGSNAELVYSIAGGNPHDLFYISPSNGEITLTKELTRKHSGLHRLVIKVSDRGKPSRHAIALVHIYVNET---------------------------------------------------IANVSHVEALVGHSLYTPLDMDIAGDPDYGLAAQRSNIVYG---SLAGVAGVVTVIVVVVFIRHRLQRETKSGYQAGKKETKDLYAPKQGPKSGKG--RKGKKGKPPKSPKPLGEDEEVSLQKSLKFNLD--GVNDSPRIHLPLTYPPGSPDLGRHYRSNSPLPSIQLQAQS---------PSASQKHQAVQELPAANTFVGTGGDDNSTGS----------DQYSDYSYKTNQPKYST-KTLPHRRVTFSTANPMQDQQDSSQQSYYDSGLEESETPSSKSSSGPRIGPLALPEDH-----------YERTTPDGSIGEMEHPETDIRSLPDVAMTGNCSQ--------ECSELGHSDACWMPGQPSPVR--KTRNPPKLSTFVPYQERGSLGRLAN------------------GSVRLGGDENRPR----LPPSRSAYSSSEHAPSDHAPLEEVPLSVTSEFPPTSPPSNHAS--KREIYL--------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q08174-1", "uniprot_id": "PCDH1_HUMAN", "id": "Q08174-1", "name": "Protocadherin-1", "aln": "MDSGAGGRRCPEAALLILGPPRMEHLRHSPGPGGQ----------------RLLLPSMLLALLLLLAPSPGHATRVVYKVPEEQPPNTLIGSLAADYGFPDVGHLYKLEVGAP------YLRVDGKTGDIFTTETSIDREG--LRECQNQLPGDPCILEFEVSITDLVQNGSPRLLEG---QIEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQAG-----------------------------------------------------------------------------------------------PEAQELFGLQVAEDQEEKQPQLIVMGNLDRERWDSY----------DLTIKVQDGGSPPRASSALLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSD-QGANAEIEYTFHQAPEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTN-------PKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGEIQVKTSLDRE----QRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENAQVQLSVEQDNG---DFVIQNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPSNTSHKLLTPQTRLGETVSQVAAEDFDSGVNAELIYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALVHLYVNET---------------------------------------------------LANRTLLETLLGHSLDTPLDIDIAGDPEYERSKQRGNILFG---VVAGVVAVALLIALAVLVRYCRQREAKSGYQAGKKETKDLYAPKPSGKASKGNKSKGKKSKSPKPVKPVEDEDEAGLQKSLKFNLMSDAPGDSPRIHLPLNYPPGSPDLGRHYRSNSPLPSIQLQPQS---------PSASKKHQVVQDLPPANTFVGTG-DTTSTGS----------EQYSDYSYRTNPPKYPS-KQVGQP----FQLSTPQPLPHPYHGAIWTEVWE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I5XVV3-1", "uniprot_id": "A0A8I5XVV3_RAT", "id": "A0A8I5XVV3-1", "name": "", "aln": "-------MRRRKTVLLILEPARMGPLRPSPGPGGQ----------------RLLLPPLLLALLLLLAPSASHTTQVVYKVPEEQPPNTLIGSLAADYGLPDVGHLYKLEVGAP------YLRVDGKTGDIFTTETSIDREG--LRECQNQISGSPCILEFEVSITDLVQNGSPRLLEG---QIEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLATDRDAGPNGVASYELQAG-----------------------------------------------------------------------------------------------PEAQELFGLQVAEDQEEKQPQLIVMGNLDRERWDSY----------DLTIKVQDGGSPPRASSALLRVTVLDTNDNAPKFERPTYEAELSENSPIGHSVIQVKANDSD-QGANAEIDYTFHQAPEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGAN-------PKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLRVQVVDVNDNAPVFTQSITEVAFPENNKPGEVVAEVTASDADSGSNAELVYSLEPEPAAQGLFTISPENGEVRVKTSLDRE----QRDSYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENARVQLSVEQDNG---DFVIQNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPFITAPSNTSHRLLTPQTRLGETVSQVTAEDIDSGINAELTYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALVHLYVNET---------------------------------------------------LANRTLLETLLVHSLDTPLDIDIAGDPEYERSKQRGNILFG---VVAGVVAVALLIALAVLVRYCRQREAKSGYQAGKKETKDLYAPKPSGKAAKGSKSKGKKSKSPKPVKPVEDEDDTGLQKSLKFNLMSDAPGDSPRIHLPLNYPPGSPDLGRHYRSNSPLPSIQLQPQS---------PSASKKHQVVQDLPPANTFVGTG-DTTSTGS----------EQYSDYSYRTNPPKYPS-KQLPHRRVTFSATSQAQELQDPSQHSYYDSGLEESETPSSKSSSGPRLGPLALPEDH-----------YERTTPDGSIGEMEHPENDLRPLPDVAMTGTCTR--------ECSEFGHSDTCWMPGQSSPSR-RTKSSALKLSTFVPYQDRGGQEPAGA-----------------GSPSPPEDRNTKTAPVRLLPSYSAFSHSSHDSCKDSATLEEIPLTQTSDFPPTATPASAQTSAKREIYL--------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q24298-1", "uniprot_id": "CADE_DROME", "id": "Q24298-1", "name": "DE-cadherin", "aln": "MSTSVQRMSRSYHCINMSATPQAGHLNPAQQQTHQQHKRKCRDLGRRLIPARLLLGVIVAISLLSPALALHSPPDKNFSGDNRKPAFKNCAGYAPKVKEEQPENTYVLTVEAVDPDPDQVIRYSIVQSPFERPKFFINPSTGVIFTTHTFDRDEPIHEKFVFVTVQATDNGLPPLDDVCTFNVTIEDINDNAPAFNKARYDESMSENAQPDAVVMTISASDFDDGNNSLVEYEILRERDFQYFKIDKESGIIYLKRPIDKRPGQSYAIIVRAYNVVPDPPQDAQIEVRIRVVESSIKPPSFVNPIDTPIYLKENLKNFTHPIATLRAVSNMPDKPEVIFELNTGRTEQTNSKNTFVFNQIGNEVTISLGKTLDYEAITDYTLTMIVRNTHELGTEHQIKIQVEDVNDNIPYYT-EVKSGTILENEPPGTPVMQVRAFDMDGTSANNIVSFELADN----REYFTIDPNTGNITALTTFDREERDFYNVKVIASDNSPSSLFDNGEPNRGHQVFRISIGDKNDHKPHFQQD-------KYLAERLLEDANTNTEVIEVKAEDEDN-ASQILYSIESGNVGDAFKIGLKTG-------KITVNQKLDYETITEYELKVRAFDG---IYDDYTTVVIKIEDVNDNPPVFKQ-DYSVTILEETTYDDCILTVEAYDPDIKDRNADQHIVYSIHQNDGNRWTIDNSGCLRLVKTLDRDPPNGHKNWQVLIKANDEDGVGTTVSTVKEVTVTLKDINDNAPFLINEMPVYWQENRNPGHVVQLQANDYDDTPGAGNFTFGIDSEATPDIKTKFSMDGDYLHANVQFDREAQKEYFIPIRISDSGVPRQSAVSILHLVIGDVNDNA--MSEGSSRIFIYNYKGEAPETDIGRVFVDDLD-DWDLEDKYFEWKDLPHDQFRLNPSTGMITMLVHTAEGEYDLS-FVVTEDSMFVPRHSVDAYVTVVVRELPEEAVDKSGSIRFINVTKEEFISVPRDFQSPDALSLKDRLQLSLAKLFNTSVSNVDVFTVLQNENHTLDVRFSAHGSPYYAPEKLNGIVAQNQQRLENELDLQMLMVNIDECLIEKFKCEESCTNELHKSSVPYMIYSNTTSFVGVNAFVQAQCVCEAPLMRRCLNGGSPRYGENDVCDCIDGFTGPHCELVSVAFYGSGYAFYEPIAACNNTKISLEITPQIDQGLIMYLGPLNFNPLLAISDFLALELDNGYPVLTVDYGSGAIRIRHQHIKMVADRTYQLDIILQRTSIEMTVDNCRLSTCQTLGAPIGPNEFLNVNAPLQLGGTPVDLEQLGRQLNWTHVPNQKGFFGCIRNLTINEQTYNLGMPSVFRNIDSGCQQSVAVAFSFGIDRNFIIAIIVCLALLLIILLAVVVQKKQKNGWHEKDIDDIRETIINYEDEGGGERDTDYDLNVLRTQPFYEEKLYKDPHALQGNMRDPNDIPDIADFLGDKKENCDRDVGATTVDDVRHYAYEGDGNSDGSLSSLASCTDDGDLNFDYLSNFGPRFRKLADMYGEEPSDTDSNVDDDQGWRI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: ** : : :.:*. . .. *.. : : * * * * :* . . : .: *: . : :. ..* :* . .: .. * * : .: : * ***:* * .. ::.**:: .::. *:* * *.:..* : :. :* *:... : : :*:..:..* * * .:. .. :. ::: : *.*** * : .. : **.* * .*:**:* * * ..* : : : : . : :* .:* * . ..***: . .. * * *.... .: .: . : : * **: * .. . .: ** * * *:..*.*: . : .: :*:* :: . .:. : .. **** : :* ::: *.*. .. .:: ::: * ***.*:*. .* : *:. .: : : * *.* . : : * :.* :: . :**: : : : . : * : .*.. : .*. :::. *::. . ** . * : : * ... :.:: : . :. . : :.:.**** :. * : :: *.* * :*: : : : * **** :: :. . : * .:*:* . : * : . *:. * :. * **: . . .* :*:. .. * : * * : *.* :.* . * .. : :. *.* * .. : . :: : : * .. : *... : .: . :.: . . : :. : . .: * .* . .*.. *::: .* * : .:.:: . : * . ** . :* :*: : : : . . . : ", "identical_positions": 149, "similar_positions": 332, "identity": "9.71%" }, { "cls_id": "homologset.agr.RGD:1308492", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q4G2Y1-1", "uniprot_id": "RIP_RAT", "id": "Q4G2Y1-1", "name": "RPA-interacting protein", "aln": "MAESSGSPHRLLYKQVGSPPWKETFRQGCLERMRNSRHKLLNRYRQAAGSTLGTASDRLLVQEVMEEEWNSLQSVENCP---------EALLQLELPLNLAVLQDIEQELWNEEKSIISEYEKGLQFDESCLNSMLAEWEAN--PLICPVCIKYNLRIMNSVVTCPCGLHIPSHSTDLTEQKLRACLEGNVNEHSAHCPHIPEFSVTGGTEEKPSLLMSCLACDTWAVIL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CWY9-1", "uniprot_id": "RIP_MOUSE", "id": "Q9CWY9-1", "name": "RPA-interacting protein", "aln": "MAESSGSPHRLLYKQVGSPHWKETFRQGCLERMRNSRHRLLNKYRQAAGSTPGTASDRLLVQEVMEEEWASLQSVENCP---------EALLQLELPLDLAVLQDIEQELCNEEKSIISEYEEDLEFDESCLRRMLAEWEAN--SLICPVCIKYNLRIMNSVVTCPCGLHIPVHSTDLTEQKLRACLEENVNEHSVHCPHTPVFSVTGGTEEKPSLLMNCLTCDTWAVIL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86UA6-1", "uniprot_id": "RIP_HUMAN", "id": "Q86UA6-1", "name": "RPA-interacting protein", "aln": "MAESLRSPRRSLYKLVGSPPWKEAFRQRCLERMRNSRDRLLNRYRQAGSSGPGNSQNSFLVQEVMEEEWNALQSVENCP---------EDLAQLEELIDMAVLEEIQQELINQEQSIISEYEKSLQFDEKCLSIMLAEWEAN--PLICPVCTKYNLRITSGVVVCQCGLSIPSHSSELTEQKLRACLEGSINEHSAHCPHTPEFSVTGGTEEKSSLLMSCLACDTWAVIL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QKJ6-1", "uniprot_id": "F1QKJ6_DANRE", "id": "F1QKJ6-1", "name": "", "aln": "MDAVQR--HRSMYKGT-TPPWKETYRKRCVERLKNSRSRLLEKFRQMTDSS-GDGKRSLLVQEVMEEEWSALKASHSLPSLWNGNPIPDVYTQQQEFDELSALEEIQQELIAQELAILEEYNNSMRYEEQYLDSVLEGMDQGG-QIICPVCHANNLTVNSHFTMCSCGLYVNTIGRNVTSEVLQNLLERRVNEHMEDCLHNPSFSMAFNTDQSTNLMISCKVCDYLSVVL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VL31-1", "uniprot_id": "RIP_DROME", "id": "Q9VL31-1", "name": "RIP-like protein", "aln": "MNSTQSPVYRTSVEQK-RHAQEVAKRQRMGNQMPRLREMLREKYRKR-----IIETRNRCTDAQREIQLSELREILRLE-----------------LSELEKDVELEELILEE---LLSDVNEWYALGEKNLETLYAEPDEQQKEVLCPVCQIKNLRHHKGAFICECGIRFEHSAN---MEQLQILLQQQIASHELQCTQALRFFIEPASG---QLYDMCGSCDYFSSV-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * : : : *: ::: . * * :::*: .: * : *: :: :::: : : ::.: :: *. * : : ::**** ** . * **: . . : *: *: : .* .* : * : : .* * ** : : ", "identical_positions": 28, "similar_positions": 51, "identity": "12.17%" }, { "cls_id": "homologset.agr.RGD:1308493", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Y6A4-1", "uniprot_id": "CFA20_HUMAN", "id": "Q9Y6A4-1", "name": "Cilia- and flagella-associated protein 20", "aln": "MFKNTFQSGFLSILYSIGSKPLQIWDKKVRNGHIKRITDNDIQSLVLEIEGTNVSTTYITCPADPKKTLGIKLPFLVMIIKNLKKYFTFEVQVLDDKNVRRRFRASNYQSTTRVKPFICTMPMRLDDGWNQIQFNLLDFTRRAYGTNYIETLRVQIHANCRIRRVYFSDRLYSEDELPAEFKLYLPVQNKAKQ------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BTU1-1", "uniprot_id": "CFA20_MOUSE", "id": "Q8BTU1-1", "name": "Cilia- and flagella-associated protein 20", "aln": "MFKNTFQSGFLSILYSIGSKPLQIWDKKVRNGHIKRITDNDIQSLVLEIEGTNVSTTYITCPADPKKTLGIKLPFLVMIIKNLKKYFTFEVQVLDDKNVRRRFRASNYQSTTRVKPFICTMPMRLDDGWNQIQFNLSDFTRRAYGTNYIETLRVQIHANCRIRRVYFSDRLYSEDELPAEFKLYLPVQNKAKQ------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6PBJ2-1", "uniprot_id": "CFA20_DANRE", "id": "Q6PBJ2-1", "name": "Cilia- and flagella-associated protein 20", "aln": "MFKNTFQSGFLSILYSIGSKPLQIWDKKVRNGHIKRITDNDIQSLVLEVEGTNVSTTYITCPADPKKTLGIKLPFLVMIIKNLKKYFTFEVQVLDDKNVRRRFRASNYQSTTRVKPFICTMPMRLDDGWNQIQFNLSDFTRRAYGTNYIETLRVQIHANCRIRRVYFSDRLYSEDELPAEFKLYLPVQNKAK-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VKV8-1", "uniprot_id": "CFA20_DROME", "id": "Q9VKV8-1", "name": "Cilia- and flagella-associated protein 20", "aln": "MFKNTFQSGFLSILYSIGSKPLQLWDKKVRNGHIKRITDNDIQSLVLEIVGTNVSTTFITCPADPKKTLGIKLPFLVMIIKNMKKYFTFEVQVLDDKNVRRRFRASNYQSTTRVKPFICTMPMRLDEGWNQIQFNLSDFTRRAYGTNYVETLRVQIHANCRIRRVYFSDRLYSEDELPPEFKLFLPIQKPVQKSNAICS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q499T7-1", "uniprot_id": "CFA20_RAT", "id": "Q499T7-1", "name": "Cilia- and flagella-associated protein 20", "aln": "MFKNTFQSGFLSILYSIGSKPLQIWDKKVRNGHIKRITDNDIQSLVLEIEGTNVSTTYITCPADPKKTLGIKLPFLVMIIKNLKKYFTFEVQVLDDKNVRRRFRASNYQSTTRVKPFICTMPMRLDDGWNQIQFNLSDFTRRAYDP-------------CKLS--YPKGLLLRQTLLRG--------------------", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***********************:************************: *******:************************:*******************************************:********* *******.. *:: * .. * : * ", "identical_positions": 141, "similar_positions": 12, "identity": "70.85%" }, { "cls_id": "homologset.agr.RGD:1308494", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QYY8-1", "uniprot_id": "SPAST_MOUSE", "id": "Q9QYY8-1", "name": "Spastin", "aln": "--------------------------------------MSSPAGRRKKKGSGGAS---------PAPARPPPPAAVPAP-----------------------------AAGPAPAA---------------------------------------------GSPPKRNPSSFSSPLVVGFALLRLLACHLGLLFAWLCQRFSRALMAAKR----------SSGTAPAPASPSPPEPGPGGEA----------------------------------------------ESVRVFHKQAFEYISIALRIDEEEKAGQKEQ---------------------------------AVEWYKKGIEELEKGIAVIVT-GQGEQYERARR------LQAKMMTNLVMAKDRLQLLEKLQPVLQFSKSQTDVYNESTNLTCRNGHLQSESGAVPKR------------------KDPLTHASNSLPRSKTVLKSGSAGLSGHHRAP--------SCSGLSMVSGARPGPGPAATTHKGTPKPNRTNKPSTP--------TTAVRKKKDLKN--------------FRNVDSNLANLIMNEIVDNGTAVKFDDIAGQELAKQALQEIVILPSLRPELFTGLRAPARGLLLFGPPGNGKTMLAKAVAAESNATFFNISAASLTSKYVGEGEKLVRALFAVARELQPSIIFIDEVDSLLCERR-EGEHDASRRLKTEFLIEFDGVQSAGD------------------DRVLVMGATNRPQELDEAVLRRFIKRVYVSLPNEETRLLLLKNLLCKQGSPLTQKELAQLARMTDGYSGSDLTALAKDAALGPIRELKPEQVKNMSASEMRNIRLSDFTESLKKIKRSVSPQTLEAYIRWNKDFGDTTV-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B2RYN7-1", "uniprot_id": "SPAST_RAT", "id": "B2RYN7-1", "name": "Spastin", "aln": "--------------------------------------MSSPAGRRKKKGSGGAS---------PAPARPPPPAAVPAP-----------------------------AAGPAPAP---------------------------------------------GSPHKRNLYYFSYPLVVGFALLRLLACHLGLLFVWLCQRFSRALMAAKR----------SSGTAPAPASPSTPAPGPGGEA----------------------------------------------ESVRVFHKQAFEYISIALRIDEEEK-GQKEQ---------------------------------AVEWYKKGIEELEKGIAVIVT-GQGEQYERARR------LQAKMMTNLVMAKDRLQLLE--------------------------------SGAVPKK------------------KDPLTHASNSLPRSKTVMKSGSTGLSGHHRAP--------SCSGLSMVSGARPGSGPAATTHKGTSKPNRTNKPSTP--------TTAVRKKKDLKN--------------FRNVDSNLANLIMNEIVDNGTAVKFDDIAGQELAKQALQEIVILPSLRPELFTGLRAPARGLLLFGPPGNGKTMLAKAVAAESNATFFNISAASLTSKYVGEGEKLVRALFAVARELQPSIIFIDEVDSLLCERR-EGEHDASRRLKTEFLIEFDGVQSAGD------------------DRVLVMGATNRPQELDEAVLRRFIKRVYVSLPNEETRLLLLKNLLCKQGSPLTQKELAQLARMTDGYSGSDLTALAKDAALGPIRELKPEQVKNMSASEMRNIRLSDFTESLKKIKRSVSPQTLEAYIRWNKDFGDTTV-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UBP0-1", "uniprot_id": "SPAST_HUMAN", "id": "Q9UBP0-1", "name": "Spastin", "aln": "--------------------------------------MNSPGGRGKKKGSGGASN--------PVPPRPPPPCLAPAPP----------------------------AAGPAPPP---------------------------------------------ESPHKRNLYYFSYPLFVGFALLRLVAFHLGLLFVWLCQRFSRALMAAKR----------SSGAAPAPASASAPAPVPGGEA----------------------------------------------ERVRVFHKQAFEYISIALRIDEDEKAGQKEQ---------------------------------AVEWYKKGIEELEKGIAVIVT-GQGEQCERARR------LQAKMMTNLVMAKDRLQLLEKMQPVLPFSKSQTDVYNDSTNLACRNGHLQSESGAVPKR------------------KDPLTHTSNSLPRSKTVMKTGSAGLSGHHRAP--------SYSGLSMVSGVKQGSGPAPTTHKGTPKTNRTNKPSTP--------TTATRKKKDLKN--------------FRNVDSNLANLIMNEIVDNGTAVKFDDIAGQDLAKQALQEIVILPSLRPELFTGLRAPARGLLLFGPPGNGKTMLAKAVAAESNATFFNISAASLTSKYVGEGEKLVRALFAVARELQPSIIFIDEVDSLLCERR-EGEHDASRRLKTEFLIEFDGVQSAGD------------------DRVLVMGATNRPQELDEAVLRRFIKRVYVSLPNEETRLLLLKNLLCKQGSPLTQKELAQLARMTDGYSGSDLTALAKDAALGPIRELKPEQVKNMSASEMRNIRLSDFTESLKKIKRSVSPQTLEAYIRWNKDFGDTTV-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NW58-1", "uniprot_id": "SPAST_DANRE", "id": "Q6NW58-1", "name": "Spastin", "aln": "--------------------------------------MNSG---HKARLRGGR------------------------------------------------------ACGPVSDG---------------------------------------------SARGNRLLFYTRSLSRVPEWLLRVLL----LLLRWLFQPIRRAMAARAK----------ECGPDGSEETG---------------------------------------------------------ERIRNYHKQAFEFISVALQIDEDEK-GDKQK---------------------------------AVQWYRKGIAELEKGIQIQVT-GAGEKADRARK------LQDKMITNLSMAEDRLKLLGNLLSQSPAESSSDDSFYSFSN---GNLRPAPASGAVSKK------------------KDTLTITNQTSLRPKNPPKS-TPNASGLNCTP--------SAAQSSRTGPQNNQKGP---TVKGK---NNVKASTTA--------TASPQRKRDMKN--------------FKNVDSKLASLILNEIVDSGSVVRFDDIAGQDLAKQALQEIVILPALRPELFTGLRAPARGLLLFGPPGNGKTMLAKAVAMESNATFFNISAATLTSKYVGEGEKLVRALFAVARELQPSIIFIDEIDSLLCERR-EGEHDASRRLKTEFLIEFDGVQSGGD------------------ERVLVMGATNRPQELDEAVLRRFAKRIYVALPTEETRLKLLKNLLSKHRNPLSQKELSQLARLTDGYSGSDLTSLAKDAALGPIRELKPEQVRNMSAHEMRDIRISDFLESLKRIKRSVSPQTLDQYVRWNREYGDTTGV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8I0P1-1", "uniprot_id": "SPAST_DROME", "id": "Q8I0P1-1", "name": "Spastin", "aln": "--------------------------MVRTKNQSSSSSASSSSTKSPIKSSSGAGSSGGGLGGRQSTHRSSSASNVAAVV----------------------------AGGSSAAGGGSSSNRRSPGSSPDGDDDTTTTDDLTPTTCSPRSGHHHSYGGYSSSVHKQNLYVVSFPIIFLFNVLRSLIYQLFCIFRYLYGASTKVIYRPHRRDCNIEIVVQNSSKEQQQSLNHPSELNREGDGQ--------EQQLSNQPQRFRPIQPLEMAANRPGGGYSPGPGDPLLAKQKHHHRRAFEYISKALKIDEENE-GHKEL---------------------------------AIELYRKGIKELEDGIAVDCWSGRGDVWDRAQR------LHDKMQTNLSMARDRLHFLALREQDLQMQRLSLKEKQKEEAQ--SKPQKTREPMLAGMT------------------NEPMKLRVRSSGYGPKATTSAQPTASGRKLTIGSKRPVNLAVANKSQTLPRNLGSKTSVGAVQRQPAKTAATPPAVRRQFSSGRNTPPQRSRTPINNNGPSGSGASTPVVSVKGVEQKLVQLILDEIVEGGAKVEWTDIAGQDVAKQALQEMVILPSVRPELFTGLRAPAKGLLLFGPPGNGKTLLARAVATECSATFLNISAASLTSKYVGDGEKLVRALFAVARHMQPSIIFIDEVDSLLSERS-SSEHEASRRLKTEFLVEFDGLPGNPDG-----------------DRIVVLAATNRPQELDEAALRRFTKRVYVSLPDEQTRELLLNRLLQKQGSPLDTEALRRLAKITDGYSGSDLTALAKDAALEPIRELNVEQVKCLDISAMRAITEQDFHSSLKRIRRSVAPQSLNSYEKWSQDYGDITI-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40328-1", "uniprot_id": "TBP6_YEAST", "id": "P40328-1", "name": "Microtubule severing ATPase YTA6", "aln": "--MAHEKFSIPENFTLAQSLQLLYSVVKNQYKNLADLIINSKGNKDTVTYGKIHKNLDTLLVYVNEGLRKIEKTYT-------------------------LKKGLGNLVVDHPELRSIIED---------------------FQILGQDIRIARRKAETLMAEGNGSPSLSSSSSVLGLGTGNGLRFPKLWRMGSKRDKLKEADEKEAKINKQADNIRRARKLEEEKKLGAKLQYERDLELQ--------REKLIELKVKEKVEFEVAQKLE--------EERVKREEEERKHREQAEKKRISTLKHERKTNYKSRAS---------------------------LDNFSSSSKSSGKIDNSLIKRRSLDVVRTSGERVRTPVR---------KSMEAAEIGMAAQLAWSQYQNGANHSKVSNNGSHSNELQIRYKPTPPLKKRYDYKKPTVN----------------RPIIKSPTLNRQNSKSSRNIPTNSK-LKASKSNTNKVSRRNEQNLEPSSPVLVSATAVPAE---SKPMRSKSGTPDKESSASSSLDSRKE--------------DILKSVQGVDRNACEQILNEILVTDEKVYWEDIAGLRNAKNSLKEAVVYPFLRPDLFKGLREPVRGMLLFGPPGTGKTMIAKAVATESNSTFFSVSASSLLSKYLGESEKLVRALFYMAKKLSPSIIFIDEIDSMLTARS-DNENESSRRIKTELLIQWSSLSSATAQSEDRNN--------TLDSRVLVLGATNLPWAIDDAARRRFSRKLYIPLPDYETRLYHLKRLMAKQKNSLQDLDYELITEMTEGFSGSDLTSLAKEAAMEPIRDLG-DKLMFADFDKIRGIEIKDFQNALLTIKKSVSSESLQKYEEWSSKFGSNGS-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P39955-1", "uniprot_id": "SAPR1_YEAST", "id": "P39955-1", "name": "Microtubule severing ATPase SAP1", "aln": "MDSQRSHHILTRLTKIRRRPQQPLTDFTELYSRIANETIYYLNLEEKKRYKEALQGWKALTTDVLFKQTLIEHNYPNTQSYTKDEVSLQNGIRELYHKSVMHLKRVKKLVREEPAPRNDMPSSKTYTNHSSSFTRSTEPPPVFQMVPGRMMKTLRNRNACGYKTAYSNPSLSSYGNSTSIKRGEDAENIRVNFVPSKPLSNNASRQHKNPIEHNDPPLKKETELYSDKYISEPILIDLTNDEDDHDVGILKGHNVFDEEESDGFEFDVSDYYDNFSEVDVEEEEEEKEERRRIKTLEAIQQQMSDLSVTSSTSSNKSVSSSENVPGSCIQSLPTTAPALPSLPPPPLLNVDRASSTGALKPHSLETSTTMDSSKIRNPQISKLMKNNHVPYLKGTKSTPTLITKSTPTFITRSKSNTKPIIKSNASSPTSSLTVPNSVIQKPKTAAMAAKRVLNSKKVASNPALNTTKKSHPILKSKTAKVPNSSSKKTSSHPSRPVSNSKPYSHGASQNKKPSKNQTTSMSKTNRKIPAQKKIGSPKIEDVGTEDATEHATSLNEQREEPEIDKKVLREILEDEIIDSLQGVDRQAAKQIFAEIVVHGDEVHWDDIAGLESAKYSLKEAVVYPFLRPDLFRGLREPVRGMLLFGPPGTGKTMLARAVATESHSTFFSISASSLTSKYLGESEKLVRALFAIAKKLSPSIIFVDEIDSIMGSRNNENENESSRRIKNEFLVQWSSLSSAAAGSNKSNTNNSDTNGDEDDTRVLVLAATNLPWSIDEAARRRFVRRQYIPLPEDQTRHVQFKKLLSHQKHTLTESDFDELVKITEGYSGSDITSLAKDAAMGPLRDLG-DKLLETEREMIRPIGLVDFKNSLVYIKPSVSQDGLVKYEKWASQFGSSGS-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . : .* : * . . : . .* : . : . : : . . . * . . : . : . .:.*: : . *: **: . * : **** ** :*:* *: * :**:** *** *.:*:*******.***::*:*** *. :**:.:**::* ***:*:.******** :*:.:.*****:**:**:: * ..*:::***:*.*:*:::..: . *::*:.*** * :*:*. *** :: *:.** :** ::.*: :: .* :..:*:*:****:*:***:**: *:*:* ::: . :* * ** .:* *: **: : * * .* .:*. ", "identical_positions": 123, "similar_positions": 127, "identity": "13.68%" }, { "cls_id": "homologset.agr.RGD:1308496", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L8U6-1", "uniprot_id": "A0ABK0L8U6_RAT", "id": "A0ABK0L8U6-1", "name": "Molybdenum cofactor sulfurase", "aln": "MACGATERGPEPPAFQRHPEASAPRLAHGYGLRSMSELRDQEFGRLAG--TVYLDHAGATLFPQSQLTNFTKDLMENVYGNPHSQNITSKLTHDTVEQVRYRVLTHFHTTPEDYSVIFTAGSTAALRLVAETFPWVSRSPENSGSHFCYLTDNHTSVVGMRTVAATMNVTSTPVKPEDMWS-AEGKGAGACDPDCQLP--HLFCYPAQSNFSGTRYPLSWIDEVKSGQRS-PVRAP------------GKWFVLLDAASYVSTSPLDLSAHQADFIPISFYKIFGLPTGLGALLVNKRVAPLLRKG-YFGGGTAAVYLAGEDFYIPRSSVAERFEDGTISFLDVIALKHGFDVLERLTG------GMVNIQQHTFALLHFTHSALSSLRYPNGAPVVRIYGDSGFSSPDVQGPIINFNVLDDAGKIIGYSQVDKMASLYNIHLRTGCFCNLGACQRHLGLSEEMVKKHFQ-AGHVCGDDVDIIDGRPTGSVRISFGYMSTLEDAQAFLRFISTIYLRSPGGQPVPQAS--TSDTGVLSSKSDCQ-----------SPQEGPCADPAVSSGSYPDINTVDLDLSQSKASSIQPIPQEKVAGILNGDLGSHIVTNIYLYPIKSCAAFEVTK---WPVGSQGLLYDRSWMVVNHNGVCLSQKQEPRLCLIQPCIDLQQKVMVIKAEGMEPIQVPLEEDGERTQIC--QSRVCADRVNTYDCGENVSRWLSKFCGRP-CHLIKQSPHFQRNAKKTPKQGHPPGTAVALSLVNEAQYLLVNTSSVLELQQQLNASDERGKEESFS-VKDLISRFRANIITKGARAFEEEQWDEISIGSLHFQGQASLLPQAFALLSLLLTTLLLDLDSEVAFLEAAQQYNSTWHTACISRADHTGCRPCLLFPSMPQRPRASWLSQFPPGSGSNSPVVFL--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14CH1-1", "uniprot_id": "MOCOS_MOUSE", "id": "Q14CH1-1", "name": "Molybdenum cofactor sulfurase", "aln": "MACGAAERGPEPPAFQRHLEASTQRLAHGYGLRSMSELRDQEFGRLAG--TVYLDHAGATLFPQSQLTNFTKDLMENVYGNPHSQNITSKLTHDTVEQVRYRILTHFHTTPEDYIVIFTAGSTAALRLVAEAFPWVSRSPENSGSHFCYLTDNHTSVVGMRKVAAAMSVTSIPVKPEDMWS-AEGKDAGACDPDCQLP--HLFCYPAQSNFSGTRYPLSWVEEVKSGRRS-PVNAP------------GKWFVLLDAASYVSTSPLDLSAHQADFIPISFYKIFGLPTGLGALLVNKHVAPLLRKG-YFGGGTAAAYLAGEDFYVPRSSVAERFEDGTISFLDVIALKHGFDALEHLTG------GMVNIQQHTFALVQYTHSALSSLRYLNGAPVVRIYSDSEFSSPDVQGPIINFNVLDDGGKIIGYSQVDKMASLYNIHLRTGCFCNLGACQRHLGLSDEMVKKHFQ-AGHVCGDDVDIIDGRPTGSVRISFGYMSTLEDAQAFLRFISTIYLRSPSDQPVPQAS--ISDAGALTSKSDCH-----------SPQEGSCTDPSVCNGSYPDTNIMDLHPSLSKASSAQQTPQDKAAGILNGDPGSHIVTNIYLYPIKSCAAFEVTK---WPVGSQGLLYDRSWMVVNHNGICMSQKQEPRLCLIQPFIDLQQRIMVIKAEGMEPIQVPLEEDGEQTQIC--QSRVCADRVNTYDCGENVSRWLSKFLGRL-CHLIKQSPHFQRNARKTPKKGQPPGTTVALSLVNEAQYLLVNTSSILELQRQLNASDEHGKEESFS-MKDLISRFRANIITKGARAFEEEKWDEISIGSLHFQ-----------VLGPCHRCQMICIN-----QQTGQRNQDVFQTLSESRGRKVNFG-VYLMHSYLDLSSPCFLSVGSEVLPVLKDCGVS--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96EN8-1", "uniprot_id": "MOCOS_HUMAN", "id": "Q96EN8-1", "name": "Molybdenum cofactor sulfurase", "aln": "MAGAAAESGRELWTFAGSRDPSAPRLAYGYGPGSLRELRAREFSRLAG--TVYLDHAGATLFSQSQLESFTSDLMENTYGNPHSQNISSKLTHDTVEQVRYRILAHFHTTAEDYTVIFTAGSTAALKLVAEAFPWVSQGPESSGSRFCYLTDSHTSVVGMRNVTMAINVISTPVRPEDLWS-AEERSASASNPDCQLP--HLFCYPAQSNFSGVRYPLSWIEEVKSGRLH-PVSTP------------GKWFVLLDAASYVSTSPLDLSAHQADFVPISFYKIFGFPTGLGALLVHNRAAPLLRKT-YFGGGTASAYLAGEDFYIPRQSVAQRFEDGTISFLDVIALKHGFDTLERLTG------GMENIKQHTFTLAQYTYVALSSLQYPNGAPVVRIYSDSEFSSPEVQGPIINFNVLDDKGNIIGYSQVDKMASLYNIHLRTGCFCNTGACQRHLGISNEMVRKHFQ-AGHVCGDNMDLIDGQPTGSVRISFGYMSTLDDVQAFLRFIIDTRLHSSGDWPVPQAHADTGETGAPSADSQADVIPAVMGRRSLSPQEDALTGSRVWNNSS-TVNAVPVAPPVCDVARTQPTPSEKAAGVLEGALGPHVVTNLYLYPIKSCAAFEVTR---WPVGNQGLLYDRSWMVVNHNGVCLSQKQEPRLCLIQPFIDLRQRIMVIKAKGMEPIEVPLEENSERTQIR--QSRVCADRVSTYDCGEKISSWLSTFFGRP-CHLIKQSSNSQRNAKKKHGKDQLPGTMATLSLVNEAQYLLINTSSILELHRQLNTSDENGKEELFS-LKDLSLRFRANIIINGKRAFEEEKWDEISIGSLRFQ-----------VLGPCHRCQMICID-----QQTGQRNQHVFQKLSESRETKVNFG-MYLMHASLDLSSPCFLSVGSQVLPVLKENVEGHDLPASEKHQDVTS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2VD33-1", "uniprot_id": "MOCOS_DANRE", "id": "A2VD33-1", "name": "Molybdenum cofactor sulfurase", "aln": "MDTRSLQDFQDLCTFDVFKSFGHY---YGYG-VDQQALIDQEFKRIKG--VTYLDHAGTTLFPESLIKGFHDDISRNVYGNPHSHNSSSRLTHDTVESVRYKILAHFNTSPEDYSVIFTSGCTAALKLVADTFPWKPMSNKEPGSQFCYLTDNHTSVVGIRGATALQGVGTISVSPREVETRARNKTQTNGEEECSTP--HLFCYPAQSNFSGRKYSLSYVKGIQSQQLY-PACEHH-----------GQWFVLLDAACFVSCSPLDLSQYPADFVPISFYKMFGFPTGLGALLVRNEAAEVLRKT-YFGGGTAAAYLVEENYFIPKPNLASRFEDGTISFLDIISLHHGFETLQKLTG------SMTNIQLHTFGLARYTYTVLSCLCHSNGKHVAQIYCDNDFQSIAEQGAIINFSLLDCHGRTVGYSQVDKMASLFNIHIRTGCFCNTGACQHYLAISNQNVKSNLH-AGHICGDNIDLVDGRPTGSLRVSFGYMSSFEDCQNFLRFVVNCFVDKP--LILDQTKLAKLNSAAPIEPSSSY-----------SPSPDRMAVSEVTMS---------------------------KDGKKDGS--SCTLTNLFIFPVKSCASFEVTE---WPLGPQGLLYDRLWMVVNENGVCLSQKREPKLCLIQPVVCLAANTLKLQISGSEAITVPLDPSLEKSDLRTSQSKVCGDRVQTVDCGEEVSAWLSEFLGKP-CRLIRQRPEFLRDMKFGQGDCCP----TPLSLVNEAQFLLINRASVCFLQEAIANRYNSDNEETWRDTEQLVQRFRANLVISAQEPFAEDNWSHLTIGNTQFQ-----------VIGKCGRCQMIGVD-----QKTATRTQEPLRSLSECRSGKVTFG-VYLAHQSARNSTHPVLSIGSHVIPKISDSTDKF-------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VRA2-1", "uniprot_id": "MOCOS_DROME", "id": "Q9VRA2-1", "name": "Molybdenum cofactor sulfurase", "aln": "MTSYRPEFS-----------------------ASEQSQIDAEFSRLASNKSVYLDHAGTTLYAESQVTAAAEQLQRNVICNPH----TCRLTGDFVDQVRFKILEFFNTTAEDYHVIFTANATAALSLVAENFDFGSSG------EFHFCQENHTSVLGMR---ERVRENGIYMLRENEISGGKHKANGKVHEVSGKTGNSLLTFSAQCNFSGYKIPLEVIEQIQIDGLAKPGKELWSSLGEKKKNMHNDYYICLDAASFVATSPLDLQKYRPDYVCLSFYKIFGYPTGVGALLVSRRGAEVFQKRRFFGGGTINYAYPHAMDYQLRETFHQRYEDGTLPFLSIVGLLEGFRTLERLVPRTDEFSTMERISRHVFGLAKYLEDQLRQLHHPNGEPLVKLYNKVGYQDKSRQGGIVAFNVRTESGSFVGFGEIACVAALHGILLRTGCFCNIGACQYYLGLDEDALDAIYKRAGRICGDYFDLIDGQPTGAVRVSFGYMTTIQDVDKLLQMLRSSYLATK---PLQRIQFIEEQAEQLPPLLKER---------------VQLLRP--------------------------------------------KLLQMAIYPVKSCAAFKIELPGSWPLTDQGLKYDREWMIVDMNGMALTQKRCTELCLIRPVIKVDQ--LELQFGENSTISVPLSLDDQAADTAKCVSKVCRQPVEGLDCGDRVAQWLSENLGMEGLRLLRQSG--QRNSSKDQQ---------KLSLVNQAQFLLLNKSSVRSLQFEEP-------------LDETVDRFRANIIIDTGSAFEELTYKALSIGGIQFQ-----------VEGPCQRCDMICIN-----QRTGERSPETLTTISRLQKGRMRFG-IYITRIPQDTKELEPKEQHMTCGDVVLVE-----------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : . ** *: . .******:**:.:* : .:: .*. *** :.:** * *:.**:::* .*:*:.*** ****:..**** ***: * : . . .* : :.****:*:* : .: : .. : . . . *: :.**.**** : .*. :. :: * ..::: ****.:*: *****. : .*:: :****:** ***:***** .. * :::* :***** : : .. .*:****:.**.::.* .** .*::*. * .*. *.* * :: * * : ** :.::* . :.. ** *: *.: * :*:.:: :*:*..* :******* **** :*.:.:: : : **::*** .*::**:***::*:*****::::* : :*::: : . : : :: . . : :: ::*:****:*:: **: *** *** **:*: **:.::**: ..****:* : : : :: ..* ***. . : :: *:** : *. ***:.:: *** * :*::* *: *****:**:**:* :*: *: .: *****:: . .* * :. ::**. :** : . :: :: .:. : . . : : : . ", "identical_positions": 218, "similar_positions": 238, "identity": "23.22%" }, { "cls_id": "homologset.agr.RGD:1308497", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AFD4-1", "uniprot_id": "A0A8I6AFD4_RAT", "id": "A0A8I6AFD4-1", "name": "", "aln": "-MESHLNQDGVPRPSYVFSADPIARPSEINFDGVKLDLSHEFSLVAANPGANSLESKNYLQVCLRIRPFTQSEK-GHEAEGCVQVLDSQTVLLKDP-QSILGHLSEKSSGQMAQKFSFSRVFGPETSQKEFFQGCIMQPVKDLLKGHSRLIFTYGLTNSGKTYTFQGTEENIGILPRTLNVLFDSLQERLYTKMSFKPHRCREYLQLSSDQEKEESANKNTLLRQIKEVTIHNDSYDILCGRLTNSLTIPEFEETMNNCEQSSLNVDN-IKYSVWVSFFEIYNESIYDLFVPVSSKLQKRKMLRLSQDVKGYSFIKDLQWIQVSDSKEAYRLLKLGVKHQSVAFTKLNNASSRSHSIFTIRILQIEDSEIPRVTRVSELSLCDLAGSERSMKTQSEGERLREAGNINTSLLTLGKCISVLKNSD-KSKIQQHVPFRESKLTHYFQSFFTGKGKICMIINISQCCSAYDETLNVLKFSTVAQKVYVPDTLSSSQEKSFGSTKSLQDVSLGSNLDNKILNVKRKTVS-WENSLEDVVENEDLVEDLEENEETQNMETELTDEDSDKPLEEGGVCAGHGKNKKLLDLIENLKKRLINEKKEKLTLEFKIREEVTQEFTQYWSQREADFKETLLHEREILEENAERRLAIFKDLVGKPGESQDEPASRFCTMELETEESHNYVGVEDIFDSLEDDVTDIKKQAELAHLYITS-LVDPQEAIACLQLKYNQVKAELAETKEELIKAQEELKNKE--SDSLVQALKTSS------------------------------------------KVDTS--LISNKSTGNETTEMPKKSRTQTHSERKRLNEDGLQLGEPPAKKGLILISPPITEDQDKREEMQQSVSEGAEEDSRVLQEKNEELKRLLTIGENELRNAKEEKAELNKQVVSLQQQLCFFEEKNSSLRAEVEQIQASYDLAAAELHTQRAVNQEQKDRILQLSGKMETAARRIESNVSQIKQMQTKIDELRSLDSPSHISKIDLLNLQDLSSGAN---LLNTSQQLPGSD-LPSTWVKEFHTQELSRESSFHSSIEAIWEECKEIVKASSKKSHQIQGLEELIEKLQVEVKNCRDENSELRAKESEDKNRDQQLKEKESLIQQLREELQETTVSLRVQVQLVAEREQALSELSRDVTCYKAKVKDLEVMVETQKEECKRLAELEQSILEKESAILKLEASLKELEAKHQDHIRSTTHLNAEEVKFREEITQLANNLHDTKQLLQSKEEENEISRQETEKLKEELAANSVLTQNLQADLQRKEEDCAELKEKFTDAKKQIEQVQREVSVMRDEEKSLRTKINELEKKKNQYSQEIDMKQRTIQQLKEQLSNQ-KMEEVVQQYEKVCKDLSVKEKLIEAMRLTLVEQEQTQAEQDRMLEAKSQEADWLAGELDTWKDKFKDLETRSNQKVTTEAMEDSDVLSEKFRKLQDELQESEEKHKADRKKWLEEKAVLTTQAKEAETLRNREMKKYAEDRERCLKLQNEVETLTAQLAEKTGELQKWREERDQLVTAVETQMQALLSSSKHKDEEIQQLRKAVAKSTGTVSGRVLENQTMNLKPECNDSVDLGGVETELQSTSFEISRNTAE------------------------------------DGSVVLDSCEVSTENVQSTRFPKPELEIQFTPLQPNKVAVKHPGCATPVTIKIPKARKRKSGEVEEDLVKCENKKNSTPRSNVKFPVSEHRNSSFKKEQKVFLCPSSKKTYSLRSQASTVGANVASKKKEGTLQKFGDFLQHSPTILQSKAKKIIETMSSPKLSTVEVSKENVSQPKKAKRKLYRNEISSPINISG-QVILMEQKAKETDHQILKRRLRTRTAK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80WE4-1", "uniprot_id": "KI20B_MOUSE", "id": "Q80WE4-1", "name": "Kinesin-like protein KIF20B", "aln": "-MESHLNPDGVPRPSYVFSADPIARPLEINFDGVKLDLSHEFSLVASNPAANSLGSKNYLQVCLRIRPFTQSEK-EHEAEGCVQVLDSQSVLLKDP-QSILGHLSEKSSGQVAQKFSFSKVFGPETSQKEFFLGCIMQPVKDLLEGHSRLIFTYGLTNSGKTYTFQGTEENIGILPRTLNVLFDSLQERLYTKMSFKPHRCREYLKLSSDQEKEESANKNTLLRQIKEVTIHNDSYDVLCGHLTNSLTIPEFEESVNSCDQSSLNVDN-IKYSVWVSFFEIYNESIYDLFVPVSSKFQKRKMLRLSQDIKGYSFIKDLQWVQVSDSKEAYRLLKLGVKHQSVAFTKLNNASSRSHSIFTIRILQIEDSEIPRVTRVSELSLCDLAGSERSMKTQNEGERLREAGNINTSLLTLGKCINVLKNSE-KSKVQ-HVPFRESKLTHYFQSFFTGKGKICMIINISQSCSAYDETLNVLKFSTTAQRVYVPDTLSSSQEKSFASNKSLQDVSLDSNLDNKILNVKRKTVS-WENSLEDVLENEDLVEDLEENEETQNMETELTDEDSDKSLEECRVSTCHKKNKELLDLIEKLNKRLINENKEKLTLELKIREEVTQEFTQYWSQREADFKETLLHEREILEENAERRLAIFKDLVGK-CDSQDEPTNRICDIELETEEAHNYVGVEDIFHSLQDDVTDIKKQAELAHLYITS-LVDPQEAIACLQLKFNQVKAELAETKEELIKAQEELKNRE--SNSLVQALKTSS------------------------------------------KVDTS--LTSNKSTCNETSEMPKNSRAQTHSERKRLNEDGLQLGEPPAKKGLILVSPPITEEQNKMGEMQQSVSEVVE-GNRVLKEKNEELKRLLTIGENELRNEKEEKAELNKQVVSLQQQLRFFEEKNSSLRADVEQIQASYNSAVAELQTQKAVNQEQRDRILKLSQEMETAARSIESNVSQIKQMQTKIDELRSLDSPSHISKIDLLNLQDLSSGAKGDNCLNTSQQLPGGD-FSSTWVKEYHTQEISRENSFHASIEAIWEECKEIVKASSKKSHQIQGLEEQIEKLQVEVKGYREENSDLRAQESQGKNRDHQLKEKESLIQQLREELQEKSVSLRVQVQLVAEREQALSELSQDVTCYKAKIKDLEVIVETQKDECKRLVELEQSILEKESAILKLEANLKECEAKHQDHIR-TNDLSAKEVKFREEVTRLANNLHDTKQLLQSKEEENEISRQETEKLKEELAANSILTQNLKADLQKKEEDCAELKEKFIDAKKQIEQVQREVSVMRDEEKLLRIKINELEKKKNQYSQDLDMKQRTIQQLKEQLSNQ-KMEEAVQQYEKVCKDLSVKEKLVEDMRLTLVEQEQTQAEQDRVLEAKSEEADWLATELDKWKEKFKDLETRSNQRLNTGTMDDLDVLTRKFSKLQDELQESEEKYKADRKKWLEEKAVLTTQAKEAENVRNREMRKYADDRERCLKLQNEVETLTAQLAEKNSELQKWREERDQLVTAVETQMKALLSSCKHKDEEIQELRKAAAKSTG------TENQTMNPKPEYNDSVDLGGVETEPQSTSLEISRNTAE------------------------------------DGSVVLDSCEVSTENVQSTRFPKPELEIQFTPLQPNKMAVKHPGCPTPVTIKIPKARKRKSGEVEEDLVKCENKKNSTPRSNVKFPVSEHRNSPVKKEQKVSVGPSSKKTYSLRSQASTVSANIASKKREGTLQKFGDFLQHSPTILQSKAKKIIETMSSPKLSTVEVSKENVSQPKKAKRKLYRNEISSPINISG-QVILMEQKVKETDHQILKRRLRTRTAK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96Q89-1", "uniprot_id": "KI20B_HUMAN", "id": "Q96Q89-1", "name": "Kinesin-like protein KIF20B", "aln": "-MESNFNQEGVPRPSYVFSADPIARPSEINFDGIKLDLSHEFSLVAPNTEANSFESKDYLQVCLRIRPFTQSEK-ELESEGCVHILDSQTVVLKEP-QCILGRLSEKSSGQMAQKFSFSKVFGPATTQKEFFQGCIMQPVKDLLKGQSRLIFTYGLTNSGKTYTFQGTEENIGILPRTLNVLFDSLQERLYTKMNLKPHRSREYLRLSSEQEKEEIASKSALLRQIKEVTVHNDSDDTLYGSLTNSLNISEFEESIKDYEQANLNMANSIKFSVWVSFFEIYNEYIYDLFVPVSSKFQKRKMLRLSQDVKGYSFIKDLQWIQVSDSKEAYRLLKLGIKHQSVAFTKLNNASSRSHSIFTVKILQIEDSEMSRVIRVSELSLCDLAGSERTMKTQNEGERLRETGNINTSLLTLGKCINVLKNSE-KSKFQQHVPFRESKLTHYFQSFFNGKGKICMIVNISQCYLAYDETLNVLKFSAIAQKVCVPDTLNSSQEKLFGPVKSSQDVSLDSNSNSKILNVKRATIS-WENSLEDLMEDEDLVEELENAEETQNVETKLLDEDLDKTLEENKAFISHEEKRKLLDLIEDLKKKLINEKKEKLTLEFKIREEVTQEFTQYWAQREADFKETLLQEREILEENAERRLAIFKDLVGK-CDTREEAAKDICATKVETEETHNYVGFEDIIDSLQDNVADIKKQAEIAHLYIAS-LPDPQEATACLELKFNQIKAELAKTKGELIKTKEELKKRENESDSLIQELETSNKKIITQNQRIKELINIIDQKEDTINEFQNLKSHMENTFKCNDKADTSSLIINNKLICNETVEVPKDSKSKICSERKRVNENELQQDEPPAKKGSIHVSSAITEDQKKSEEVRPNIAEIED--IRVLQENNEGLRAFLLTIENELKNEKEEKAELNKQIVHFQQELSLSEKKNLTLSKEVQQIQSNYDIAIAELHVQKSKNQEQEEKIMKLSNEIETATRSITNNVSQIKLMHTKIDELRTLDSVSQISNIDLLNLRDLSNGSEEDNLPNTQLDLLGNDYLVSKQVKEYRIQEPNRENSFHSSIEAIWEECKEIVKASSKKSHQIEELEQQIEKLQAEVKGYKDENN--RLKEKEHKNQDDLLKEKETLIQQLKEELQEKNVTLDVQIQHVVEGKRALSELTQGVTCYKAKIKELETILETQKVECSHSAKLEQDILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVKELKLKEEITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINELEKKKNQCSQELDMKQRTIQQLKEQLNNQ-KVEEAIQQYERACKDLNVKEKIIEDMRMTLEEQEQTQVEQDQVLEAKLEEVERLATELEKWKEKCNDLETKNNQRSNKEHENNTDVLG-KLTNLQDELQESEQKYNADRKKWLEEKMMLITQAKEAENIRNKEMKKYAEDRERFFKQQNEMEILTAQLTEKDSDLQKWREERDQLVAALEIQLKALISSNVQKDNEIEQLKRIISETSK------IETQIMDIKPKRISSADPDKLQTEPLSTSFEISRNKIE------------------------------------DGSVVLDSCEVSTENDQSTRFPKPELEIQFTPLQPNKMAVKHPGCTTPVTVKIPKARKRKSNEMEEDLVKCENKKNATPRTNLKFPISDDRNSSVKKEQKVAIRPSSKKTYSLRSQASIIGVNLATKKKEGTLQKFGDFLQHSPSILQSKAKKIIETMSSSKLSNVEASKENVSQPKRAKRKLYTSEISSPIDISG-QVILMDQKMKESDHQIIKRRLRTKTAK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GXF8-1", "uniprot_id": "A0AC58GXF8_DANRE", "id": "A0AC58GXF8-1", "name": "", "aln": "MMESCLNHK-------------PDRVDSITVEDLRKDLFSEFSKLSRDSVS---LEKEHLQVYLRVRPFTSTERAEGESQDCISIEPPDTVILKAPKASLTARHSERFGPQLAQRFQFSQVYGPETTQKEIFDGTTKSLVKEVLDGGNSLIFTYGVTNAGKTFTFLGPESDGGILPRSLNVIFNSIEGRIYLQNNIKPHRCVDFTRLTKEQQDEEATNKRNLLRRFKDNDSQK---TLSSMSSSSCSSFDSSTSSDMNGDSVYLDEDSHVKFSVWVSFCEIYNESIHDLLDFVPNGSHRRNALRLAQDVKSNSFVKDLKWVQVNSADEALKVVKIGRKNQSFSSTKLNNISSRSHSIFSIRMLRIEDVGVPRVQTISELSLCDLAGSERCARTQNRGERLKEAGNINTSLLTLGKCINALRLNQTQSKFHQHIPFRESKLTHYLQGYFCGRGKACMIININQCASVYDETLNVLKFSAVAQKVVVLNPKPAPS---IALKRSARDVSMIINNADKKDWTRRSSIMGWEMSLEDVQEDENDEDMDEEEVESDDESIVDR-TVLETVE-NQELCELQVK-------IEELQEKLIKEESEKLTLEARIREEVTTEFMELFSNMEKDYSERLQREKEIVEERAERRLEILKNLVNR-----TIEE---MTTDENAAKEAKMELLDTMIEAMRSDLTKIKGDAESVQLCLAN-VPESPGKLSHLRTELEEIKAELLKSQQQLSLKSKEFEESCIQMQDLNDQLLQAT----------------------------------------------------RNYENQKVRCQELMSICQEKDDMVSKLQTALEQNDEAASKDRALINNIREEILHFKNSCKCKLNEEHD--EMTS-QKNQQLQQELKMKDDQLNQLKLEHASLEKAMRDISDRLSELTQTHEATVAMERAEVNKVTNENKALANELDELQQRAN---EMSSKVETIQTELGNQSKKANELSEELHTARALIR---------EHQEESCSHSQTIESLMIEAAHLRLELSTCQLSRDRKEAECERMVALSQEKNRQISDLEQELKQTRESVCQLEELCSR---LKSERDAQAQEYQSLLNR-YEAQN-------LVVTQIRSNSDLLEELTALKHQHKKIEKQDDCWKTVQDNLIQTVSKLNQQEEILSIVQ-------------------------------------------TIVTNEIS-KARDEANMKITEMEKDLSNKNTELETKAQELMKVREHVNDGHNQIERMRCDLQQVEQERSDVRDQLCEANTQKEHLEKQILILSEESKMFQQRLCEAEKMKDQPRPCLSCIEQTIDPLQIEQSNHVLEKEDIQLFQTPCQES----KLIEETPVTLN-TEFKRTDEEELLKPRLTEIEFITEDLATLQEKNQNPR----------------------------VGVSDHSQQED------------GRAQRPEEHTRQQLVKKQD-------------------------------------TILKLQKDSVVSPNSDTQEADKLKQTSN---------------------------MKTKNEGDSVSPTQEQVAEQ--------------------------------------------DSSVLSTKSLREERFPKPELEISFTPLKPHRMNVRKPGEEESVTIKLRRTARKRKSTEIENSVESENCKNRRLKVNNRANMQSVETPTVQ-------GKKMSQLK--QKDSPAS----LKGKKDGPLQKIGDFIQSSPTLFGSKAKKIMSMVNVKSPEP-LNASENN-KPKRSKRKLFKTQVSSPMDIPSYPIIGSSDDDKESDHLIIKRKLRTRTAKR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1RFH9-1", "uniprot_id": "A0A8M1RFH9_DANRE", "id": "A0A8M1RFH9-1", "name": "", "aln": "MMESGLKDD-------------PARPAILVVEDLRRNLSTEFDCSDLQDSS---DLKEHLKVYLRIRPFSAVEIENGESQDCVTIQRPDTVLLKPPQTSLSARLSDKSVPVTAQRFQFSQVYGPDTTQKDIFDGTVNGLVRNVLEGQNSLVFTYGVTNAGKTFTFLGPDTNPGILPRSLNMIFSSLEGRIFTQMCLKPQRCRDFIRLTKEQQNEEAASKRNLLKLFKESDAQR---NISGHCSKS-DIEDGSMLSDVNSAVLDVEMDMHTRFSIWVSFCEIYNENIHDLLEQHASNASRKTNLRLCQDVKGNSFIKDLKWVQVSSAEEALKVMKLGKRNQSISSTKLNLLSSRSHSIFSVRILKVEDVGIPRVESVSELALCDLAGSERCAKTQNKGERLKEAGNINTSLLSLGKCINALRNNQ---QARQHVPFRESKLTHYLQGYFTGRGSACMIVNINQCSSMYDETLNVLKFSAVAQKVVVLTTKNIP----VGVKRSAREVSFIINNADCR-EMRRSSLVRWDPSLEDVQEDSDTEDEYEDQSEIEDTILNSEDECTETVQINKKLYEGQQRL------IVNTQQQLTAVQAELLTLEARVRDEVTKEFSELISQMQEDYSERMSRERELVEERCERRLEILKNLVEK-----TAMEDDRMNSTVAKSEEEKRVSLDSLFDSMSGDLAGIRNDAQAAQSCLVTSDPRVSATLHDLEKKVTELSEQLSISQNQLLLKTKELET----QSRLSDELEEVR----------------------------------------------------KTLESHREREFNLSDMCRQKDEMIAKLQATLDQHVERKAEDRAQMDSVQKKVIQCCCTIKEPLSSRNE--TRKRRQEGEGLEGQPPLKKGPPEDLKMPEDEADDGREDS--ALLEVKGQLECCLAEAKQKDKQITDLEQECHRLQVCIQDQKS---NLDERVSQEHILKEDVCQTTLE-SKQMATAVDFSN---------LNVAVASRCSNTTGAFAAKSLMAKRDLELREK--NKHILTLEKEIALMRQKAEHTSDYENLKKLNSELQAEVKSLCKVKAELKEKITCLQKEKEGLEDKEVGLTN-------PNTLGFKSKERDNQTHLMLSGKEAEIALRENALTLKETQLSALQKSLKQTQERLEEEE-------------------------------------------MQAVQEARRKEVERRREILAVAEEAIAQKDAELQKRQEEISRLKEEIKTSECKMSSLTVDLRRREDDSSDLREKLCDSKKQIQQVQKEISSMREAEKSLRLKLSDLEKTKVQLQNEIANRDRTINQLKAERSSGSKSDENLLLYQKACKDLQERERVIEDMRLALTEQEETQTQLDLELDNRNARIDELTQELASLREMLPEERDRSDSRPIS---KDVLQARQQITQAHESLQLANEKQQAERKKWMEEKLILIGQAKEAEERRNQDMRRFADDRERHVRQQAEMESLAARLNAREEEMERWRKERDTLVSALEVQLKKLIMSNGEKDQQIKMLQSSNTAQTPEEVSEDSRTEALQAELAVKEAEIQKLKEQLSLSATNSSIRRNSTTQTMEVEFSDMKPLNSSTIKHKSRTRGSVISQNSSGSGPLVLDSSEISTETGRRSRFPRPELEISFSPLQPDRFALKRQGEESAVTVKISRPTRKRKSGEMDKRKGARSSAVKKKAFSEPNPQDAVEGENIRNTR----CRLTPHLTPHREESPNSQESNQRGKKDKTLQKIGDFLQSSPTFLGSKAKRIMGLMSGKSPDGGSTPSLKL-KSKRDKRKYDRPDISSPMDIPAHRIIGRNPEDKESGNLIKKR-LRTRMAK-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *** :: . * : .:.:: :* **. : : *::*:* **:***: * *::.*: : .::*:** * .: .: *:: **:*.**:*:** *:**::* * *:::*.* . *:****:**:***:** *.: : *****:**::*.*:: *:: : :**:*. :: :*:.:*:.** :.* **: :*: :. .. : . :: ::*:**** ***** *:**: .. ::. ***.**:*. **:***:*:**..:.** :::*:* ::**.: **** ********::::*::** :.** :***:********* :**..****:*:********:*****..*: .: : : *:**********:*.:* *:*. ***:**.*. ***********: **:* * . . .. :* ::**: * . :* :: *: ****: *:.: : *: * :: :. : : . * . :::* : * **** ::*:*** ** : :: : *:.* : :*:*::**..**** *:*:** : : : .: ::.:: .::: *: :*: .: :.. *. : ::. :* :: :* :*:: . * : * .. :. . : .: : *: :. :. : . : : . : ::.: *. .. .: * . . :. * . . *:: . ::. .:. . . :: : : . :: . : : : .: :: . .: :: * . : ::: * . *: : .* . : * : .. : * : : . . . : .::: : :. : . : : . : :. : *: * : :* :::*.: . . : **:: *:: ::::::: :::.* ::::::: : : .* :: :: : ** * * : ::**: *: : .. .* : :: *:: :::* ::* * .:.: : *. : . : :: :* . :: : . : ::.. : : :*:..* .::: : : : :: * . :: . ..:: : : : *.: . . **. :**:. : ***:*****.*:**:*.:. ::: * .**:*: :. :::.. :. ... . . . .: : :.::. *:: .***:***:* **::: ****:*: :. . . .. : :.*: *** ::***::*.. :* . . **:.: * ** ***: ** ", "identical_positions": 332, "similar_positions": 521, "identity": "17.69%" }, { "cls_id": "homologset.agr.RGD:1308498", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VE52-1", "uniprot_id": "OGRL1_MOUSE", "id": "Q8VE52-1", "name": "Opioid growth factor receptor-like protein 1", "aln": "MGNLLGGVSFREPTTVEDCDSTWQTDSEPEPEQPGPAGGGEGQQHDEPEQPKQPPERAGGRPRASPVPEDHAEAAGAEQGGESTEGNAKPKRSFYAARDLYKYRHQYPNFKDIRYQNDLSNLRFYKNKIPFKPDGVYIEEVLNKWKGDYEKLEHNHTYIQWLFPLREQGLNFYAKELTTYEIEEFKKTKEAIRRFLLAYKMMLEFFGIKLIDKTGNVARAGNWQERFQHLNESQHNYLRITRILKSLGELGYESFKSPLVKFILHEALVENTIPNIKQSALEYFVYTIRDRRERRKLLRFAQKHYTPSENFIWGPPKKELPERSKAQKTPTLPASGSNGQTSTHKKSKDSKISPGASHVNSKSVEEKKGASREPGEEADKPSPEPGSGDPKPRNTEKDSAADQSDSPPEKTVPDTAGKGECP-TSSEKDGEGEDQSKDSENPENAGCHAEVVAQQNATNPQTSSG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4KLH3-1", "uniprot_id": "OGRL1_RAT", "id": "Q4KLH3-1", "name": "Opioid growth factor receptor-like protein 1", "aln": "MGNLLGGVSFREPTTVEDCDSTWQTDSEPEPEQPGPAGGGEGQEQDEREQPEQPPERAGGRPRASPVPEDHAEAAGAEQGGDSTEGNAKPKRSFYAARDLYKYRHQYPNFKDIRYQNDLSNLRFYKNKIPFKPDGVYIEEVLNKWKGDYEKLEHNHTYIQWLFPLREQGLNFYAKELTTYEIEEFKKTKEAIRRFLLAYKMMLEFFGIKLIDKTGNVARAVNWQERFQHLNESQHNYLRITRILKSLGELGYESFKSPLVKFILHEALVENTIPNIKQSALEYFVYTIRDRRERRKLLRFAQKHYTPSENFIWGPPKKEQPERSKAQKTPTLPALGSNGQTSTHKKSKDSKNSSAASHLNNKTVEEKKVASREPGEETDKPSPEASSEDTKPRNSEDDNAADQSESPPKKTVNDSAGKGECPTTSSEKDGEGENQSKDSENPENTSCHAEVVSQQNVTNPQTSSG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5TC84-1", "uniprot_id": "OGRL1_HUMAN", "id": "Q5TC84-1", "name": "Opioid growth factor receptor-like protein 1", "aln": "MGNLLGGVSFREPTTVEDCDSTWQTDSEPEPEEPGPGGGSEGPGQ-ESEQPAQPPEQAGGRPGASPAPDEDAEAAGAEQGGDSTEATAKPKRSFYAARDLYKYRHQYPNFKDIRYQNDLSNLRFYKNKIPFKPDGVYIEEVLSKWKGDYEKLEHNHTYIQWLFPLREQGLNFYAKELTTYEIEEFKKTKEAIRRFLLAYKMMLEFFGIKLTDKTGNVARAVNWQERFQHLNESQHNYLRITRILKSLGELGYESFKSPLVKFILHEALVENTIPNIKQSALEYFVYTIRDRRERRKLLRFAQKHYTPSENFIWGPPRKEQSEGSKAQKMSSPLASSHNSQTSMHKKAKDSKNSSSAVHLNSKTAEDKKVAPKEPVEETDRPSPEPSNEAAKPRNTEKDSNAENMNSQPEKTVTTPTEKKESV--SPENNEEGGNDNQDNENPGNTNCHDVVLVQ-----------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "********************************:***.**.** : * *** ****:***** ***.*::.**********:***..*******************************************************.******************************************************************* ********* ***********************************************************************************************:** .* ***** .: * . *.*** ***:**** *..* *:*.*:.*:** *.:** **:*:****... .****:*.*. *:: :* *:*** .: * *. *.*:: ** ::.:*.*** *:.** *: * ", "identical_positions": 360, "similar_positions": 56, "identity": "77.42%" }, { "cls_id": "homologset.agr.RGD:1308499", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JUC1-1", "uniprot_id": "A0A0G2JUC1_RAT", "id": "A0A0G2JUC1-1", "name": "", "aln": "MAAVAVLRNDSLQAFLQDRTPSASPDLGKHSPLALLAATCSRIGQPGAAAAPDFLQVPYDPALGSPSRLFHPWTADMPAHSPGALPPPHPSLGLTPQKTHLQPSFGAAHELPLTPPADPSYPYEFSPVKMLPSSMAALPASCAPAYVPYAAQAALPPGYSNLLPPPPPPPPPPTCRQLSPAPAPDDLPWWSIPQSGAGPGSSGVPGTSLSSACAGPPHAPRFPASAAAAAAAAAALQRGLVLGPSDFAQYQSQIAALLQTKAPLAATARRCRRCRCPNCQAAGGAPEAEPGKKKQHVCHVPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKSFTRSDELQRHLRTHTGEKRFACPECGKRFMRSDHLAKHVKTHQNKKLKVAEAGVKRENPRDL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JHX2-1", "uniprot_id": "SP5_MOUSE", "id": "Q9JHX2-1", "name": "Transcription factor Sp5", "aln": "MAAVAVLRNDSLQAFLQDRTPSASPDLGKHSPLALLAATCSRIGQPGAAAAPDFLQVPYDPALGSPSRLFHPWTADMPAHSPGALPPPHPSLGLTPQKTHLQPSFGAAHELPLTPPADPSYPYEFSPVKMLPSSMAALPASCAPAYVPYAAQAALPPGYSNLLPPPPPPPPPPTCRQLSPAPAPDDLPWWSIPQSGAGPGSSGVPGTSLSSACAGPPHAPRFPASAAAAAAAAAALQRGLVLGPSDFAQYQSQIAALLQTKAPLAATARRCRRCRCPNCQAAGGAPEAEPGKKKQHVCHVPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKSFTRSDELQRHLRTHTGEKRFACPECGKRFMRSDHLAKHVKTHQNKKLKVAEAGVKRENPRDL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6BEB4-1", "uniprot_id": "SP5_HUMAN", "id": "Q6BEB4-1", "name": "Transcription factor Sp5", "aln": "MAAVAVLRNDSLQAFLQDRTPSASPDLGKHSPLALLAATCSRIGQPGAAAPPDFLQVPYDPALGSPSRLFHPWTADMPAHSPGALPPPHPSLGLTPQKTHLQPSFGAAHELPLTPPADPSYPYEFSPVKMLPSSMAALPASCAPAYVPYAAQAALPPGYSNLLPPPPPPPPPPTCRQLSPNPAPDDLPWWSIPQAGAGPGASGVPGSGLSGACAGAPHAPRFPASAAAAAAAAAALQRGLVLGPSDFAQYQSQIAALLQTKAPLAATARRCRRCRCPNCQAAGGAPEAEPGKKKQHVCHVPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKSFTRSDELQRHLRTHTGEKRFACPECGKRFMRSDHLAKHVKTHQNKKLKVAEAGVKREDARDL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**************************************************.********************************************************************************************************************************* *************:*****:*****:.**.****.*********************************************************************************************************************************************************************************:.***", "identical_positions": 388, "similar_positions": 9, "identity": "97.49%" }, { "cls_id": "homologset.agr.RGD:1308500", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q61818-1", "uniprot_id": "RAI1_MOUSE", "id": "Q61818-1", "name": "Retinoic acid-induced protein 1", "aln": "MQSFRERCGFHGKQQNYPQTSQETSRLENYRQPGQAGLSCDRQRLLAKDYYSPQPYTGYEGGTGTPSGTVATAAADKYHRGS------KSLQGRPAFPSY-VQDSSPYPGRYSGEEGLQTWGGPQPPPPQPQPLPGAVSKYEENLMKKTVVPPPNRQYPEQGPQLPFRTHSLHVP-PPQPQQPLAYPKLQRQKPQNDLASPLPFPQGSHFPQHSQSFPTSSTYAPTVQGGGQGAHSYKSCTAPSAQPHDRPMSANANLAPGQRVQNLHAYQPGRLGYEQQQQ----------ALQGRHHTQETLHYQNLAKYQHYGQQGQGYCPPDTAVRTPEQYYQTFSPSSSHSPARSVGRSPSYSSTPSPLMPNLENFPYSQQPLSTGAFPTGITDHSHFMPLLNPSPTDAASSVDPQAGNCKPLQKEKLPDNLLSDLSLQSLTALTSQVENISNTVQQLLLSKATMPQKKGVKNLVSRTPEQHKSQHCSPEGSGYSAEPAGTPLSEPPSSTPQSTHAEPQDTDYLSGSEDPLERSFLYCSQARGSPARVNSNSKAKPESVSTCSVTSPDDMSTKSDDSFQSLHSTLPLDSFSKFVAGERDCPRLLLSALAQEDLASEILGLQEAIVEKADKAWAEASSLPKDNGKPPFSLENHGACLDTVAKTSWSQPGEPETLPEPLQLDKGGSTKDFSPGLFEDPSVAFATTDPKKTSSPLSFGTKPLLGTATPDPTTAAFDCFPDTPTASSVDGANPFAWPEENLGDACPRWGLHPGELTKGLEQGAKASDGVGKADAHEASACMGFQEDHAIGKPAAALSGDFKQQEAEGVKEEVGGLLQCPEVAKANQWLEESRHCCSSTDFGDLPLLPPPGRKEDLEAEEEYSSLCELLGSPEQRPSLQDPLSPKAPLMCTKEEAEEALDTKAGWVSPCHLSGEPAVLLGPSVGAQSKVQSWFESSLSHMKPGEEGPEMERAPGSSGTSQGSLAPKPNKPAVPEGPIAKKEPVPRGKSLRSRRVHRGLPEAEDSPCRVPALPKDLLLPESCTGPPQGQAEGAGAPGRGLSEGLPRMCTRSLTALSEPQTPGPPGLTTTPTPPDKLGGKQRAAFKSGKRVGKPSPKAASSPSNPAALPVASDSSPMGSKTKEPDSPSMPGKDQRSMVLRSRTKPQQVFHAKRRRPSESRIPDCRATKKLPANNHLPTAYKVSSGPQKEGRMNQRVKVPKPGTGNKLSDRPLHTLKRKSAFMAPVPAKKRSLILRSNN-------GSGGDGREERAESSPGLLRRMASPQRARP-RGSGEPPP-PPPLEPPAACMGLSTQSSLPSAVRTKVLPPRKGRGLKLEAIVQKITSPGLKKLACRVAGAPPGTPRSPALPER-----RPGGSPAGAEEGLGGMG--QMLPAASGADPLCRNPAS-RSLKGKLLNSKKLSSAADCPKAEAFMSPETLPSLGTARAPKKRSRKGRTGTLGPSKGPLEKRPCPGQPLLLAPHDRASSTQGGGEDNSSGGGKKPKTEELGPASQPPEGRPCQPQTRAQKQPGQASYSSYSKRKRLSRGRGKTAHASPCKGRATRRRQQQVLPLDPAEPEIRLKYISSCKRLRADSRTPAFSPFVRVEKRDAYTTICTVVNSPGDEPKPHWKPSSSAASSSTSSSS-LEPAGASLTTFPGGSVLQQRPSLPLSSTMHLGPVVSKALSTSCLVCCLCQNPANFKDLGDLCGPYYPEHCLPKKKPKLKEKARLEGTLEEASLPLERTLKGLECSASTTAAAPTTATITTPTALGRLSRPDGPADPAKQGPLRTSARGLSRRLQSCYCCDGQGDGGEEVAQADKSRKHECSKEAPTEPGGDTQEHWVHEACAVWTSGVYLVAGKLFGLQEAMKVAVDMPCTSCHEPGATISCSYKGCIHTYHYPCANDTGCTFIEENFTLKCPKHKRLPL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K4G0-1", "uniprot_id": "A0A0G2K4G0_RAT", "id": "A0A0G2K4G0-1", "name": "", "aln": "MQSFRERCGFHGKQQNYPQTSQETSRLENYRQPGQAGLSCDRQRLLAKDYYNPQPYTGYEGGTGTPAGTVATAAADKYHRGN------KSLQGRPAFPSY-VQDSSPYPGRYSGEEGLQTWGSPQPPPPQPQPLPGAVSKYEENLMKKTVVPP-NRQYPEQGPQLPFRTHGLHVP-PPQPQQPLAYPKLQRQKPQNDLASPLPFPQGSHFPQHSQSFPTSSTYAPTVQGGGQGAHSYKSCTAPSAQPHDRPMSANASLAPGQRVQNLHAYQPGRLGYEQQQQ----------ALQGRHHTQETLHYQNLAKYQHYGQQGQGYCPADTAVRTPEQYYQTFSPSSSHSPARSVGRSPSYSSTPSPLMPNLENFPYSQQPLSTGAFPTGITDHSHFMPLLNPSPTDAASSVDPQVSNCKPLQKEKLPDNLLSDLSLQSLTALTSQVENISNTVQQLLLSKATIPQKKGVKNLVSRTPEQHKSQHCSPEGSGYSAEPAGTPLSEPPSSTPQSTHAEPQDTDYLSGSEDPLERSFLYCSQARGSPARVNSNSKAKPESVSTCSVTSPDDMSTKSDDSFQSLHSTLPLDSFSKFVAGERDCPRLLLSALAQEDLASEILGLQEAIVEKADKAWAEASSLPKDNGKPPFSLENHSTCLDTVAKTSWSQPGEPEALPEPLQLDKGGSTKDFSPGLFEDPSVAFATTDPKKTTSPLSFGTKPLLGTATPDPTTAAFDCFPDTTTASSVDGANPFAWPEENLGDACPRWGLHPGELTKGLEQGAKASDSVGKADAHETSACLGFQEEHAIGKPAAALSGDFKQQEADGVKEEVGGLLQCPEVGKADQWLEDSRHCCSSADFGDLPLLPPPGRKEDLEAEEEYSSLCELLGSPEQRPSLQDPLSPKAPLICTKEEAEEVLDTKAGWASPCHLSGEPAVLLGPSVGAESKVQSWFESSLSHMKPGE-GPELERAPGSASTSQGSLAPKPNTPAVPEGPIAKKEPVPRGKSLRSRRVHRGLPEAEDSPCRAPALPKDLLLPESCTGPPQGQAEGAGAPGRGLSEGLPRMCTRSLTALSEPQTPGPPGLTTTPTPPDKLGGKQRAAFKSGKRVGKPSPKAASSPSNPAALPVASDSSPMGSKTKEPDSPGMPGKDQRSMVLRSRTKPQQVFHAKRRRPSESRIPDCRPTKKPPANNHLPTAFKVSSGPQKEGRMSQRGKVPKPGTGSKLSDRPLHTLKRKSAFMAPVPAKKRSLILRSNN-------GSGVDGREERAESSPGLLRRMASPQRARP-RGSGEPPP-PPPLEPPAACLGLATQSSLPSAVRTKVLPPRKGRGLKLEAIVQKITSPGLKKLACRVAGAPPGTPRSPALPEK-----RSGGSPAGAEEGVGGMGAGQMLPAASGADPLCRNPASSRSLKGKLLNSKKLSSAADCPKAEAFMSPETLPSLGTARAPKKRSRKGRTGALGPSKGPLEKRPCPGQALILAPHDRASSTQGGGEDNSSGGGKKPKTEELGLASQPPEGRPCQPQTRAQKQPGQASYSSYSKRKRLSRGRGKATHASPCKGRATRRRQQQVLPLDPAEPEIRLKYISSCKRLRADSRTPAFSPFVRVEKRDAYTTICTVVNSPGDEPKPHWKPSSVASSSTSSS----EPAGASLTTFPGGSVLQLRPSLPLSSTMHLGPVVSKALSTSCLVCCLCQNPANFKDLGDLCGPYYPEHCLPKKKPKLKEKVRLEGTLEEASLPLERTLKGLECAASTTAATPTTTTITTTTTLGRLSRPDGPADPAKQGSLRTSARGLSRRLQSCYCCDGQGDGGEEVAPADKSRKHECSKEAPAEPGGDTQEHWVHEACAVWTSGVYLVAGKLFGLQEAMKVAVDMPCTSCHESGATISCSYEGCTHTYHYPCANDTGCTFIEENFTLKCPKHKRLPL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7Z5J4-1", "uniprot_id": "RAI1_HUMAN", "id": "Q7Z5J4-1", "name": "Retinoic acid-induced protein 1", "aln": "MQSFRERCGFHGKQQNYQQTSQETSRLENYRQPSQAGLSCDRQRLLAKDYYNPQPYPSYEGGAGTPSGTAAAVAADKYHRGSKALPTQQGLQGRPAFPGYGVQDSSPYPGRYAGEESLQAWGAPQPPPPQPQPLPAGVAKYDENLMKKTAVPP-SRQYAEQGAQVPFRTHSLHVQQPPPPQQPLAYPKLQRQKLQNDIASPLPFPQGTHFPQHSQSFPTSSTYSSSVQGGGQGAHSYKSCTAPTAQPHDRPLTASSSLAPGQRVQNLHAYQSGRLSYDQQQQQQQQQQQQQQALQSRHHAQETLHYQNLAKYQHYGQQGQGYCQPDAAVRTPEQYYQTFSPSSSHSPARSVGRSPSYSSTPSPLMPNLENFPYSQQPLSTGAFPAGITDHSHFMPLLNPSPTDATSSVDTQAGNCKPLQKDKLPENLLSDLSLQSLTALTSQVENISNTVQQLLLSKAAVPQKKGVKNLVSRTPEQHKSQHCSPEGSGYSAEPAGTPLSEPPSSTPQSTHAEPQEADYLSGSEDPLERSFLYCNQARGSPARVNSNSKAKPESVSTCSVTSPDDMSTKSDDSFQSLHGSLPLDSFSKFVAGERDCPRLLLSALAQEDLASEILGLQEAIGEKADKAWAEAPSLVKDSSKPPFSLENHSACLDSVAKSAWPRPGEPEALPDSLQLDKGGNAKDFSPGLFEDPSVAFATPDPKKTTGPLSFGTKPTLGVPAPDPTTAAFDCFPDTTAASSADSANPFAWPEENLGDACPRWGLHPGELTKGLEQGGKASDGISKGDTHEASACLGFQEEDPPGEKVASLPGDFKQEEVGGVKEEAGGLLQCPEVAKADRWLEDSRHCCSTADFGDLPLLPPTSRKEDLEAEEEYSSLCELLGSPEQRPGMQDPLSPKAPLICTKEEVEEVLDSKAGWGSPCHLSGESVILLGPTVGTESKVQSWFESSLSHMKPGEEGPDGERAPGDSTTSDASLAQKPNKPAVPEAPIAKKEPVPRGKSLRSRRVHRGLPEAEDSPCRAPVLPKDLLLPESCTGPPQGQMEGAGAPGRGASEGLPRMCTRSLTALSEPRTPGPPGLTTTPAPPDKLGGKQRAAFKSGKRVGKPSPKAASSPSNPAALPVASDSSPMGSKTKETDSPSTPGKDQRSMILRSRTKTQEIFHSKRRRPSEGRLPNCRATKKLLDNSHLPATFKVSSSPQKEGRVSQRARVPKPGAGSKLSDRPLHALKRKSAFMAPVPTKKRNLVLRSRSSSSSNASGNGGDGKEERPEGSPTLFKRMSSPKKAKPTKGNGEPATKLPPPETPDACLKLASRAAFQGAMKTKVLPPRKGRGLKLEAIVQKITSPSLKKFACKAPGASPGNPLSPSLSDKDRGLKGAGGSPVGVEEGLVNVGTGQKLPTS-GADPLCRNPTN-RSLKGKLMNSKKLS-STDCFKTEAFTSPEALQPGGTALAPKKRSRKGRAGAHGLSKGPLEKRPYLGPALLLTPRDRASGTQGASEDNSGGGGKKPKMEELGLASQPPEGRPCQPQTRAQKQPGHTNYSSYSKRKRLTRGRAKNTTSSPCKGRAKRRRQQQVLPLDPAEPEIRLKYISSCKRLRSDSRTPAFSPFVRVEKRDAFTTICTVVNSPGDAPKPHRKPSSSASSSSSSSSFSLDAAGASLATLPGGSILQPRPSLPLSSTMHLGPVVSKALSTSCLVCCLCQNPANFKDLGDLCGPYYPEHCLPKKKPKLKEKVRPEGTCEEASLPLERTLKGPECAAAATAGKP--------------PRPDGPADPAKQGPLRTSARGLSRRLQSCYCCDGREDGGEEAAPADKGRKHECSKEAPAEPGGEAQEHWVHEACAVWTGGVYLVAGKLFGLQEAMKVAVDMMCSSCQEAGATIGCCHKGCLHTYHYPCASDAGCIFIEENFSLKCPKHKRLP-", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***************** ***************.*****************.****..****:***:**.*:.********. :.********.* ***********:***.**:**.************..*:**:*******.*** .***.***.*:*****.*** ** ************** ***:*********:***************:.:*****************:*******::*.:.**************.***.*:**** ***.***:*********************** .*:*********************************************************:*******************:****.*..*******:***:*********************************::******************************************************::*****************.*******************************************.:**************************************** **********.** **..*********.:***:***::*.:*****:**:.*******.:*****************.*****:.******** **..:**************.:***.*.********************************.****.:.*.*:**:***:****:.. *: .*:*.*****:*. *****.*********.**::***:******::**********..*************************.:**********:*****.**.**:**** ********..:****:**::****************** **: *****.: **:.*** ***.*****.********************************.*.****************** ********* ******************:***********:***************************************************.***. ********:******.*::**:*******.*:*:**.*** *.***:::****.******:.** :*****:*.********:************:***.*:***.. *.* **:***.*.** *::**:**::*:* :*.***.. ** *.* **: *:::::: .*::************************.***:**:..**.**.* **:*.:: .****.*.***: .:* * **:: *********:. *******:****** ::** *:*** ***:* . *** **********:*: * ********* * .*:*:*:****.***..****.******* **** *********************::.**********:***.* : :*******.*****************************:******************:************ **** **** *:**::** :.*****:*:****:** **************************************************************.* *** ************* **:*::**. * .************.********************: *****.* ***.**********:****::*************.********************** *:**:*.****.*.::** ********.*:** ******:********** ", "identical_positions": 1543, "similar_positions": 264, "identity": "80.16%" }, { "cls_id": "homologset.agr.RGD:1308501", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BXN7-1", "uniprot_id": "PPM1K_MOUSE", "id": "Q8BXN7-1", "name": "Protein phosphatase Mn(2+)-dependent 1K", "aln": "MLSAAFITLLRSGGNQVKKRVLLSSILLQDHRQATPA-CYFSTSEARCS--RFDPDGSGQPATWDNFG-IWDNRIDEPILLPPSIKYGKPIPKISLENVGCASLIGK--RKENEDRFGFAQLTEEVLYFAVYDGHGGPAAADFCHTHMEKCVMD-------------------LLPREKDLETVLTLAFLEIDKAFASYAHLSADAS-LLTSGTTATVALLRDG-------------VELVVASVGDSRALLCRK-GKPMKLTTDHTPERKDEKERIKKFGGFVAWNSLGQPHVNGRLAMTRSIGDLDLKASGVIAEPETTRIKL---------------YHADDSFLVLTTDGINFMVNSQEICDFVNQCHD----PKEAAHSVTEQAIQYG------TEDNSTAVVVPFGAWGKYKNSEITFSFSRSFASSGRWA-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6K136-1", "uniprot_id": "PPM1K_RAT", "id": "A6K136-1", "name": "Protein phosphatase Mn(2+)-dependent 1K", "aln": "MLSTAFITLVRSGRNQVKKRVLLSSILLQDHRQMTPA-CYCSISEPRCS--RFDPDGSGQPATWDNFG-IWDNRIDEPILLPPSIKYGKPIPKISLENVGCASLIGK--RKENEDRFGFAQLTEEVLYFAVYDGHGGPAAADFCHTHMEKCVTD-------------------LLPREKDLETVLTLAFLEIDKAFSSYAHLSADAS-LLTSGTTATVALLRDG-------------VELVVASVGDSRALLCRK-GKPMKLTTDHTPERKDEKERIKKCGGFVAWNSLGQPHVNGRLAMTRSIGDLDLKASGVIAEPETTRIKL---------------YHADDSFLVLTTDGINFMVNSQEICDFVNQCHD----PKEAAHAVTEQAIQYG------TEDNSTAVVVPFGAWGKYKNSEITFSFSRSFASSGRWA-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N3J5-1", "uniprot_id": "PPM1K_HUMAN", "id": "Q8N3J5-1", "name": "Protein phosphatase Mn(2+)-dependent 1K", "aln": "MSTAALITLVRSGGNQVRRRVLLSSRLLQDDRRVTPT-CHSSTSEPRCS--RFDPDGSGSPATWDNFG-IWDNRIDEPILLPPSIKYGKPIPKISLENVGCASQIGK--RKENEDRFDFAQLTDEVLYFAVYDGHGGPAAADFCHTHMEKCIMD-------------------LLPKEKNLETLLTLAFLEIDKAFSSHARLSADAT-LLTSGTTATVALLRDG-------------IELVVASVGDSRAILCRK-GKPMKLTIDHTPERKDEKERIKKCGGFVAWNSLGQPHVNGRLAMTRSIGDLDLKTSGVIAEPETKRIKL---------------HHADDSFLVLTTDGINFMVNSQEICDFVNQCHD----PNEAAHAVTEQAIQYG------TEDNSTAVVVPFGAWGKYKNSEINFSFSRSFASSGRWA-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P874-1", "uniprot_id": "A0A8M1P874_DANRE", "id": "A0A8M1P874-1", "name": "protein-serine/threonine phosphatase", "aln": "MSVALLVRYATLSGSRVCSRAAFN--LTNAHQEDPRR-ALHTPSSPRFSNSRFDPDSSGRPTTWDSFG-IWDNRIDEPILLPSSIRYGKLIPKVNLSRVGSASQIGQ--RKENEDRYQMSQMTDNIMYFAVFDGHGGAEAADFCHKNMEKHIKD-------------------IAAEETNLEFVLTKAFLEVDKALARHLHFSADAS-VLSAGTTATVALLRDG-------------IELVVGSVGDSRAMMCRK-GKAVKLTVDHTPERKDEKERIRRSGGFITWNSLGQPHVNGRLAMTRSIGDFDLKATGVIAEPETKRISL---------------HHVHDSFLALTTDGINFIMNSQEICDVINQCHD----PKEAAQRISEQALQYG------SEDNSTIIVVPFGAWGKHKSSEVSFSFSRSFVSSGRFA-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ACD6B5Q7-1", "uniprot_id": "A0ACD6B5Q7_DANRE", "id": "A0ACD6B5Q7-1", "name": "protein-serine/threonine phosphatase", "aln": "-MSVSAVCFSR---------------LLRCARCVHPA-RCVRVPGVRWHTTRLDMDGSGRPATWDSFG-IWDNRIEEPILLPPSIRYGTPIPHISLSRVGCATLIGR--RRENEDRFQVSELTQNVLYFALFDGHGGAHAADYCHKHMEQNIRD-------------------CLEMETDLQTVLSKAFLEVDAALEEKLQIYGNAS-LMMVGTTATVALLRDG-------------IELVVGSVGDSRALLCRK-GKSRKLTDDHTPERKDEKHRIRQSGGFVTWNSVGQANVNGRLAMTRSIGDFDLKKSGVIAEPEITRTLL---------------QHAHDSFLVLTTDGVNFIMSNQEICDIINLCHD----PTEAANVIAEQALQYG------SEDNSTVIVVPFGAWGKHQNTDYTHDMSRNFASIGRWS-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P25646-1", "uniprot_id": "PDP2_YEAST", "id": "P25646-1", "name": "[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial", "aln": "MRLGNAYAYCKPSQNVGLKLDLLRGLPGYVGHATSRINRLENQDNYSIKMMRSWPNAYGSALNCSVFDGHGEKGAQLSQLLADKLCSSLDFPEPSWDKQDLKKLVQEYARRFPEGNYWKHKLSTFEKFYNKFIKNCNSKQELLLMKEGDSAILGQNGGRMIFDKMGNIIDKIALLTELDRLRLFYGFARFDLDQCCGLGTAAGSTASSIFLYPYDDPNAPIDEGKDDDSWIISHSGLLKLIVTQVGDSKIILCDQDGIAHALTTTHHINSSRERHRLSIDPSRLDPDAFGETRFLNNFANTRSFGDVAGKPYGISSEPDIFSFLVGNTLHLPRSERSKLPFNGDECFLALVTDGITNKLADQEVVDLITSTVNSWGLKKATPQFVAEETIKFIQAIATKHSDNATCVVVRLSNWGNWPNVDRTGPQRETKLMNAQSNETKLN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * :. * . . . *. :: : . **. .: . :*. . .. . . : . *: *..: ::: :: : : .. .. :. : . *. . * :::* . . *: :: . * : :* ::*:* .****: ::* : * . ** * : . *:.*: . : ::.*:... ..:* ***:**. * *: :**: : : .:.**.*.***:. : .**: *.:. : . :.: ::*::::: .**:* :** :. **: . : . .. .: ", "identical_positions": 55, "similar_positions": 127, "identity": "12.44%" }, { "cls_id": "homologset.agr.RGD:1308502", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5M934-1", "uniprot_id": "TRUB1_RAT", "id": "Q5M934-1", "name": "Pseudouridylate synthase TRUB1", "aln": "MAAEEAEVVSP--LIVDTAP--DTSGTAAASLA-----AAVSAAAAAARTGSQAQVSKAALAAKLMSLSGVFAVHKPKGPTSAELLNRLKEKLLAEAGLPSPEWNKRQKQTLKVGHGGTLDSAAQGVLVVGIGRGTKMLTSMLSG-SKRYIATGELGKATDTLDSTGKVTEEKPYDKITQEDIEGILQKFTGNIMQVPPLYSALKKDGQRLSTLMKRGE-TVEARPARPVTVHSISLL--------------------------------------------------------------------------KYQPPFFTLDVECGGGFYIRSLVSDIGKELSSCATVLELTRTKQGPFTLAQHALPE--------------------DRWTINDIAQSLKRCTSLLPEELTFKKSKSEPSSDQALSCGYITLRETKREDDTVKTL---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C0D0-1", "uniprot_id": "TRUB1_MOUSE", "id": "Q8C0D0-1", "name": "Pseudouridylate synthase TRUB1", "aln": "MAAAEAEVVSP--LIVDTAP--DTSGTAEASVA-----ASV---AEAARTESQAPASKAALAAKLMSLSGVFAVHKPKGPTSAELLNRLKEKLLAEAGMPSPEWNKRQKQTLKVGHGGTLDSAAQGVLVVGIGRGTKMLTSMLSG-SKRYITIGELGKATDTLDSTGKVTEEKPYDKITREDIEGILQKFTGNIMQVPPLYSALKKDGQRLSTLMKKGK-VVEARPARPVTVHSISLL--------------------------------------------------------------------------KFQPPFFTLDVECGGGFYIRSLVSDIGKELSSCASVLELTRTKQGPFTLAQHALPE--------------------DRWTIDDIEQSLERCTSLLPEELTFKKLKSDNSSDQVISCGYITLRDTKREDDAVKTL---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WWH5-1", "uniprot_id": "TRUB1_HUMAN", "id": "Q8WWH5-1", "name": "Pseudouridylate synthase TRUB1", "aln": "MAASEAAVVSSPSLKTDTSPVLETAGTVAAMAATPSARAAAAVVAAAARTGSEARVSKAALATKLLSLSGVFAVHKPKGPTSAELLNRLKEKLLAEAGMPSPEWTKRKKQTLKIGHGGTLDSAARGVLVVGIGSGTKMLTSMLSG-SKRYTAIGELGKATDTLDSTGRVTEEKPYDKITQEDIEGILQKFTGNIMQVPPLYSALKKDGQRLSTLMKRGE-VVEAKPARPVTVYSISLQ--------------------------------------------------------------------------KFQPPFFTLDVECGGGFYIRSLVSDIGKELSSCANVLELTRTKQGPFTLEEHALPE--------------------DKWTIDDIAQSLEHCSSLFPAELALKKSKPE-SNEQVLSCEYITLNEPKREDDVIKTC---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P48567-1", "uniprot_id": "PUS4_YEAST", "id": "P48567-1", "name": "tRNA pseudouridine synthase 4", "aln": "----------------------------------------------MNGIFAIEKPSGITSNQFMLKLQHALTKSQVFSKEIQRATAERKQQYEKQTGKKASKRKLRKVSKVKMGHGGTLDPLASGVLVIGIGAGTKKLANYLSGTVKVYESEALFGVSTTSGDVEGEILSQNSVKHLNFDDLKTVEEKFVGQLKQTPPIYAALKMDGKPLHEYAREGKPLPRAIEPRQVTIYDLKVFSDSLKRDHDYPLLRPTTEEAVDTVKNLNANMLNDVLYFSKEYTEKHGLDSEVAKVEEPFPLSEQEEQEIQKEGDSYRAPKLHFKANVSSGTYIRSLVSDIGKSMRSSCYMVKLIRLQQQDWSLEKNNVFQLTDFTERDEKVWSKVLEKVLDEGATVDVIEELKKAEKEIPADVKECIVSSDQPGDEATAETIETANAEEHSNTLKRKIEQV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : ::.*. .:: : . . . *:: ::* :.: . *: ..:*:*******. * ****:*** *** *:. *** * * : . :* :* : * *.: .::. .::. :*:: : :**.*:: *.**:*:*** **: * :.*: .* .* **::.:.: .::.* : :..: ..* ***********.: *.. :::* * :* ::* :: : : *. : *: :.*::. . :* :: ..: ..::. : * . ::.: :. ", "identical_positions": 76, "similar_positions": 121, "identity": "16.93%" }, { "cls_id": "homologset.agr.RGD:1308503", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q62176-1", "uniprot_id": "RBM38_MOUSE", "id": "Q62176-1", "name": "RNA-binding protein 38", "aln": "MLLQPA-CSPSV-FPRPSAAPSAMHGSQKDTTFTKIFVGGLPYHTTDASLRKYFEGFGDIEEAVVITDRQTGKSRGYGFVTMADRAAADRACKDPNPIIDGRKANVNLAYLGAKPRSLQTGFAVGVQQLHPTLIQRTYGLTPHYIYPPAIVQPSVVIPATPVPSLSSPYLEYTPASPAYAQYPPATYDQYPYAASPAAATSFVGYGYPAAVPQALSAAAPAGTTFVQYQAPQLQPDRMQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZGE9-1", "uniprot_id": "D3ZGE9_RAT", "id": "D3ZGE9-1", "name": "RNA-binding protein 38", "aln": "MLLQPA-CAPSV-FPRPSAAPSAMHGSQKDTTFTKIFVGGLPYHTTDASLRKYFEGFGDIEEAVVITDRQTGKSRGYGFVTMADRAAADRACKDPNPIIDGRKANVNLAYLGAKPRSLQTGFAVGVQQLHPTLIQRTYGLTPHYIYPPAIVQPSVVIPATPVPSLSSPYLEYTPASPAYAQYPPATYDQYPYAASPATATSFVGYGYPAAIPPALSATAPAGTTFVQYQAPQLQPDRMQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H0Z9-1", "uniprot_id": "RBM38_HUMAN", "id": "Q9H0Z9-1", "name": "RNA-binding protein 38", "aln": "MLLQPAPCAPSAGFPRPLAAPGAMHGSQKDTTFTKIFVGGLPYHTTDASLRKYFEGFGDIEEAVVITDRQTGKSRGYGFVTMADRAAAERACKDPNPIIDGRKANVNLAYLGAKPRSLQTGFAIGVQQLHPTLIQRTYGLTPHYIYPPAIVQPSVVIPAAPVPSLSSPYIEYTPASPAYAQYPPATYDQYPYAASPATAASFVGYSYPAAVPQALSAAAPAGTTFVQYQAPQLQPDRMQ", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****** *:**. **** ***.******************************************************************:**********************************:***********************************:*********:***************************:*:*****.****:* ****:*********************", "identical_positions": 223, "similar_positions": 12, "identity": "93.31%" }, { "cls_id": "homologset.agr.RGD:1308506", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5Y6U5-1", "uniprot_id": "A0A8I5Y6U5_RAT", "id": "A0A8I5Y6U5-1", "name": "Signal recognition particle 14 kDa protein", "aln": "---MVLLESEQFLTELTRLFQKC-RSSGSVFITLK------------KYDGRTKP---IPRKS---SVEGLEPAENKCLLRAT----DGKRKISTVVSSKEVNKFQMECEACSSLWNTSQELLKECRHRGTRVASIGVAVGFLMPATLSPMESLLLPSLYLFLLRPCSGFQAYSNLLRANMDGLKKRDKKNKSKKSKPAQ--------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P16254-1", "uniprot_id": "SRP14_MOUSE", "id": "P16254-1", "name": "Signal recognition particle 14 kDa protein", "aln": "---MVLLESEQFLTELTRLFQKC-RSSGSVFITLK------------KYDGRTKP---IPRKS---SVEGLEPAENKCLLRAT----DGKRKISTVVSSKEVNKFQM----------------------------------------------------------------AYSNLLRANMDGLKKRDKKNKSKKSKPAQ--------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P37108-1", "uniprot_id": "SRP14_HUMAN", "id": "P37108-1", "name": "Signal recognition particle 14 kDa protein", "aln": "---MVLLESEQFLTELTRLFQKC-RTSGSVYITLK------------KYDGRTKP---IPKKG---TVEGFEPADNKCLLRAT----DGKKKISTVVSSKEVNKFQM----------------------------------------------------------------AYSNLLRANMDGLKKRDKKNKTKKTKAAAAAAAAAPAAAATAPTTAATTAATAAQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VDL0-1", "uniprot_id": "Q9VDL0_DROME", "id": "Q9VDL0-1", "name": "Signal recognition particle 14 kDa protein", "aln": "---MVLLDNSNFILRLEKIANAA-KKDSSFTLTFK------------RYDGNDKP---VPREG---RPPLPKPETYMCLMRAQ----SKSQKISTVVRQEDVPAMMS----------------------------------------------------------------MYSQFMKSKMDGLKRVKKVKSKAKATKG---------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38985-1", "uniprot_id": "SRP14_YEAST", "id": "P38985-1", "name": "Signal recognition particle subunit SRP14", "aln": "MANTGCLSPGAFLSKVPEFFQTANEKHITVRLTAKRLIEHDPVEGNLEFDSTNHPDYDVSKKASEISVSSRSDREYPLLIRMSYGSHDKKTKCSTVVKASELDQFWQ----------------------------------------------------------------EYSSVFKGGMQNLIKKKKKKSKNGTISKTGKKNKVAKKN----------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. *: .: .: : . .. :. :* * .:*. :* :.::. . *:* . . * **** .:: : **..::. *:.* : .* :.. : ", "identical_positions": 18, "similar_positions": 43, "identity": "7.96%" }, { "cls_id": "homologset.agr.RGD:1308507", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K7N9-1", "uniprot_id": "A0A0G2K7N9_RAT", "id": "A0A0G2K7N9-1", "name": "Rho GTPase-activating protein 5", "aln": "MMAKNKEPRPPSYTVSVVGLSGTEKDKGNCGVGKSCLCNRFVRSKADEYYPEHTSVLSTIDFGGRVVNNDHFLYWGDITQNGEDGVECKIHVIEQTEFIDDQTFLPHRSTNLQPYIKRAAASKLQSAEKLMYICTDQLGLEQDFEQKQMPEGKLNVDGFLLCIDVSQGCNRKFDDQLKFVNNLFVQLSKSKKPVIIAATKCDECVDHYLREVQAFASNK---KNLLVVETSARFNVNIETCFTALVQMLDKTRGKPKIIPYLDAYKTQRQLVVTATDKFEK-LVQTVRDYHATWKTVSNKLKNHPDYEEYINLEGTRKARNTFSKHIEQLKQEHIRKRREEYISTLPRAFNTLLPDLEEIEHLN---WLEALKLMEKRADFQLCFVVLEKTPWDETDHIDKINDRR-IPFDLLSTLEAEKVYQNHVQHLISEKRRIEMKEKFKKTLEKIQFISPGQPWEEVMCFVMEDEAFKYITEADSKEVYGRHQREIVEKAKEEFQEMLFEHSELFYDLDLNATPSSDKMSEIHTVLSEEPRYKALQKLAPDRESLLLKHIGFVYHPTKETCLSGQYCTDIKVENLLANSLLHSDHNRSR---LYHDSTNIDKVNLFILGKDGLAQELANEIRTQS-TDDEYALDGKIYELDLRPVDAKSPYILSQLWTAAFKPHGCFCVFNSIESLSFIGEFIGKIRTEASQIRKDKYMANLPFTLILANQRDSISKNLPILRHQGQQLANKLQCPFVDVPAGTYPRKFNESQIKQALRGVLESVKHNLDVVSPVPINKDVSEADLRIVMCAMCGDPFSVDIILSPFLDSHSCSAAQAGQNNSLMLDKIIGEKRRRIQITILSYHSSIGVRKDELVHGYILVYSAKRKASMGMLRAFLSEVQDTIPVQLVAVTDS--QADFFENEAIKELMTEGEHIATEITAKFTALYSLSQYHRQTEVFTLFFSDVLEKKNMIENSYLSD----NTRESTHQSEDVFLPSPRDCFP-YNNYPDSDDDTEAPPPYSPIGDDVQLLPTPSDRSRYRLDLEGNEYPVHSTPNCHDHERN--------------------------------------------------HKVPPPIKPKP-VVPKTNVKKLDPNLLKTIEAGIGKNPRKQTSRVPLAHPEDMDS-------------SDNYAEPLDTIFKQ------KGYPDEIYVVPDDSQNRIIKIRNSFVN-NTQGDEENGFSDRTSKGHGERRPSKYKYKSKTLFSKAKSYYRRTHSDASDDEAFPTSKTKRKGR------------HRGSEEDPLLSPVETWKGG-------------IDNPAITSDQEVDDKKIKKK-PHKVKEDKK-KKKTKTFN---PPTRRNWESNYFGMPLQDLVTAEK-PIPLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQDHNINLASMEVTVNAVAGALKAFFADLPDPLIPYSLHPELLEAAK-------------IPDKTERLHALKEIVKKFHPVNYDVFRYVITHLNRVSQQNKINLMTADNLSICFWPTLMRPDFENR-EFLSTTKIHQSVVETFIQQCQFFFYNGEIVETANTVAAPPTSNPGQLVESMVPLQLPPPLQPQLIQPQLQTDPLGII", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97393-1", "uniprot_id": "RHG05_MOUSE", "id": "P97393-1", "name": "Rho GTPase-activating protein 5", "aln": "MMAKNKEPRPPSYTVSVVGLSGTEKDKGNCGVGKSCLCNRFVRSKADEYYPEHTSVLSTIDFGGRVVNNDHFLYWGDITQNGEDGVECKIHVIEQTEFIDDQTFLPHRSTNLQPYIKRAAASKLQSAEKLMYICTDQLGLEQDFEQKQMPEGKLNVDGFLLCIDVSQGCNRKFDDQLKFVNNLFVQLSKSKKPVIIAATKCDECVDHYLREVQAFASNK---KNLLVVETSARFNVNIETCFTALVQMLDKTRGKPKIIPYLDAYKTQRQLVVTATDKFEK-LVQTVRDYHATWKTVSNKLKNHPDYEEYINLEGTRKARNTFSKHIEQLKQEHIRKRREEYISTLPRAFNTLLPDLEEIEHLN---WLEALKLMEKRADFQLCFVVLEKTPWDETDHIDKINDRR-IPFDLLSTLEAEKVYQNHVQHLISEKRRIEMKEKFKKTLEKIQFISPGQPWEEVMCFVMEDEAFKYITEADSKEVYGRHQREIVEKAKEEFQEMLFEHSELFYDLDLNATPSSDKMSEIHTVLSEEPRYKALQKLAPDRESLLLKHIGFVYHPTKETCLSGQYCTDIKVENLLATSLLEMDHNRVR---LYHDSTNIDKVNLFILGKDGLAQELANEIRTQS-TDDEYALDGKIYELDLRPVDAKSPYILSQLWTAAFKPHGCFCVFNSIESLSFIGEFIGKIRTEASQIRKDKYMTNLPFTLILANQRDSISKNLPILRHQGQQLANKLQCPFVDVPTGTYPRKFNESQIKQALRGVLESVKHNLDVVSPVPINKDVSEADLRIVMCAMCGDPFSVDLILSPFLDSHSCSAAQAGQNNSLMLDKIIGEKRRRIQITILSYHSSIGVRKDELVHGYILVYSAKRKASMGMLRAFLSEVQDTIPVQLVAVTDS--QADFFENEAIKELMTEGEHIATEITAKFTALYSLSQYHRQTEVFTLFFSDVLEKKNMIENSYLSD----NTRESTHQSEDVFLPSPRDCFP-YNNYPDSDDDTEAPPPYSPIGDDVQLLPTPSDRSRYRLDLEGNEYPVHSTPNCHDHERN--------------------------------------------------HKVPPPIKPKP-VVPKTNVKKLDPNLLKTIEAGIGKNPRKQTSRVPLAHPEDMDS-------------SDNYVEPLDTIFKQ------KGYSDEIYVVPDDSQNRIIKIRNSFVN-NTQGDEENGFSDRTSKGHGERRPSKYKYKSKTLFSKAKSYYRRTHSDASDDEAFTTSKTKRKGR------------HRGSEEDPLLSPVETWKGG-------------IDNPAITSDQEVDDKKIKKK-THKVKEDKKQKKKTKTFN---PPTRRNWESNYFGMPLQDLVTAEK-PIPLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQDHNINLASMEVTVNAVAGALKAFFADLPDPLIPYSLHPELLEAAK-------------IPDKTERFHALKEIVKKFHPVNYDVFRYVITHLNRVSQQNKINLMTADNLSICFWPTLMRPDFENR-EFLSTTKIHQSVVETFIQQCQFFFYNGEIVETANTVAPPPTSNPGQLVESMVPLQLPPPLQPQLIQPQLQTDPLGII", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13017-1", "uniprot_id": "RHG05_HUMAN", "id": "Q13017-1", "name": "Rho GTPase-activating protein 5", "aln": "MMAKNKEPRPPSYTISIVGLSGTEKDKGNCGVGKSCLCNRFVRSKADEYYPEHTSVLSTIDFGGRVVNNDHFLYWGDIIQNSEDGVECKIHVIEQTEFIDDQTFLPHRSTNLQPYIKRAAASKLQSAEKLMYICTDQLGLEQDFEQKQMPEGKLNVDGFLLCIDVSQGCNRKFDDQLKFVNNLFVQLSKSKKPVIIAATKCDECVDHYLREVQAFASNK---KNLLVVETSARFNVNIETCFTALVQMLDKTRSKPKIIPYLDAYKTQRQLVVTATDKFEK-LVQTVRDYHATWKTVSNKLKNHPDYEEYINLEGTRKARNTFSKHIEQLKQEHIRKRREEYINTLPRAFNTLLPNLEEIEHLN---WSEALKLMEKRADFQLCFVVLEKTPWDETDHIDKINDRR-IPFDLLSTLEAEKVYQNHVQHLISEKRRVEMKEKFKKTLEKIQFISPGQPWEEVMCFVMEDEAYKYITEADSKEVYGRHQREIVEKAKEEFQEMLFEHSELFYDLDLNATPSSDKMSEIHTVLSEEPRYKALQKLAPDRESLLLKHIGFVYHPTKETCLSGQNCTDIKVEQLLASSLLQLDHGRLR---LYHDSTNIDKVNLFILGKDGLAQELANEIRTQS-TDDEYALDGKIYELDLRPVDAKSPYFLSQLWTAAFKPHGCFCVFNSIESLSFIGEFIGKIRTEASQIRKDKYMANLPFTLILANQRDSISKNLPILRHQGQQLANKLQCPFVDVPAGTYPRKFNETQIKQALRGVLESVKHNLDVVSPIPANKDLSEADLRIVMCAMCGDPFSVDLILSPFLDSHSCSAAQAGQNNSLMLDKIIGEKRRRIQITILSYHSSIGVRKDELVHGYILVYSAKRKASMGMLRAFLSEVQDTIPVQLVAVTDS--QADFFENEAIKELMTEGEHIATEITAKFTALYSLSQYHRQTEVFTLFFSDVLEKKNMIENSYLSD----NTRESTHQSEDVFLPSPRDCFP-YNNYPDSDDDTEAPPPYSPIGDDVQLLPTPSDRSRYRLDLEGNEYPIHSTPNCHDHERN--------------------------------------------------HKVPPPIKPKP-VVPKTNVKKLDPNLLKTIEAGIGKNPRKQTSRVPLAHPEDMDP-------------SDNYAEPIDTIFKQ------KGYSDEIYVVPDDSQNR-IKIRNSFVN-NTQGDEENGFSDRTSKSHGERRPSKYKYKSKTLFSKAKSYYRRTHSDASDDEAFTTSKTKRKGR------------HRGSEEDPLLSPVETWKGG-------------IDNPAITSDQELDDKKMKKK-THKVKEDKKQKKKTKNFN---PPTRRNWESNYFGMPLQDLVTAEK-PIPLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQDHNINLVSMEVTVNAVAGALKAFFADLPDPLIPYSLHPELLEAAK-------------IPDKTERLHALKEIVKKFHPVNYDVFRYVITHLNRVSQQHKINLMTADNLSICFWPTLMRPDFENR-EFLSTTKIHQSVVETFIQQCQFFFYNGEIVETTNIVAPPPPSNPGQLVEPMVPLQLPPPLQPQLIQPQLQTDPLGII", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R372-1", "uniprot_id": "F1R372_DANRE", "id": "F1R372-1", "name": "", "aln": "-MAKNKETR-PTYAVSVVGLSGTEKEKGNCGVGKSCLCNRYVRPSADCYYLEHTSVLSTIDFGGRVVNNDHFLYWGEVLHRGDDGVECRIQVIEQTEFIDDQTFLPHRSTNLQPYTKRAANTKLQSAEKLMYICTDQLGLEQDFDQKQMPDGKLNIDGFVLCIDISKGCNRKFDDQMKFVHSLYSQISKAKKPIIIAATKCDECVEQYLREVQTFVTGK---KNLMLVETSARASVNVELCFNALTQQIDKTRGKPKIISYLEAYKSQRQLVASVSDKFEKLIVQTVRDYHTSWKIVSNKLKSHPDYEEYINLEGTKKARNTFSKHIEQLRQEHIKRRREDYLTSLPKIFNKLLNNLEEIETMS---WTEAQSLMRSRHEFQYCFIELEHTPWYETDHLDKTDDRR-VPFDILQTMQGERIYQNHVQHLISEKRRLEMKEKFKKTLERVHFISPGQPWEEVMCFVMEDEAYKYITESDRRDVYSRHQQEIVERAKEEFQEMLFEHAELFYDLDLNATPSYDKMSEIHAVLNEEPRYRALQKLATDRESLLLKHIGFVYHPTKETCLSGTACIDLKVEQVLANRLVQLDHGRSN---IYYNSANIEKVNLCLVGREGLAQELANEIRAQS-TDDEYTLDGKIYELDLLPVDVNSGMLLNHSWISTFKPHGFFCVFSSIESLNYIGDRVSRIRAEIAQSRRDRYSQPVPFILILANQRDSVCKNMPILRHQGQQLANKLQCTFVDIPTGTFPRKFNESQIKQALRAVLEGLKHNFDMMSPMPSIKDLSETDLRIVMCAMCGDPFSVDLILSPFLDSHSCSAGQPGQCNTLILDKIIGNGRRRIQVTVLSYHSSIGIRKDELVHGYILVYSAKRKSSMAMLRAFLAEVQDVIPVQLVAITDS--QADFFENEAIKELMTEGEHIATEIAAKFTALYSLSQYHRQTEVFTPFFNEVLEKKSNIESSFMFD----NSRDGTGTTEDVFPQSPHSHSPAYQYYPDSEDDGEGPPPYSPIGDDVQLLPNPSER-KYRIDLEGNEYPIHSTP-VGEHERN--------------------------------------------------HKVPPPVKPKPNVLPKPNVKKLDPNLLRTIEAGMRTS--RWTRGPMMGHSDDLEA-------------SDNYAEPADTLQHKS-----KGYSDDIYAVPEDAHSRSGKTRNSFGGLVVHVDEENGFDS-MSKSQGGRRPSKYKHRSKILFSKTKAYHRRVHSDVSDDESGPATQKKKKGRG-----------NRGSEEDPLLSPVDPWKGG-------------IDNPAITSDPEQDERKTKKKKAPKTKEPKKPTRSTKTTKPLYPPTRRNWESNYFGVPLQNLVTPDR-PIPLFVEKCVDYIERTGFTTEGLYRVCGNKTDQDNIQKQFDQDHSIDLIVMDVAVNAVAGALKAFFADLPDPLIPYSLHPELVEAAK-------------IVDHYERLQVLKEIVRKFPPVNYEVFKYVITHLNRVSQHSKTTLMTADNLSICFWPTLMRPDFENK-DTLSTTKLNQSVIESFIQQCQYFFYGGDMTEPSSAEGTPPPHGHG--LESLLALQLPPPLQPQQIQHPLPPEPLI--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VX32-1", "uniprot_id": "RG190_DROME", "id": "Q9VX32-1", "name": "Rho GTPase-activating protein 190", "aln": "---------MRQFNISVIGLSGTEKDRGQVGVGKSCLCNRFMRPMADDYFIDHISVLSQSDFSGRIVNNDHFLYWGDVRKTTEEGVEYQFNIIEQTEFMDDSTFQAFKVGKMDPYSKRCTATKVFSAEKLMYICKNQLGIEKEYEQKVMPDGRLSIDGFVVVFDVSPVPNRSVEKQVEFVQNVIATILKNKKPLVLVTTKNDDAYELYVREAEKISQRKDYKSTVQLIETSAHESINIDLAFLLLAQMIDKVKNRVKIISYQESAKSRKELLDTRSEAVTRLIRNQITDYHVLWSQGSKMLSQYREWNEFLNIFGHEAGQKLFRRHMKKLRDDHLNKKLHQYLDKFALALEYLLPDIGALNISDDDAWECARNYLQNHIEFEQYFFECPQASWTELVDMDEAEDEARIPFDVLETSEAETVFRNYLNSVQQDKKKIGWKQQFKMLLEESGFVTPGKQLSEVRVLFMGRECFEALSEHDCQQIYDIHQDDIIEKSKQNFVELLLEHAQYFLQFKNVDNITQEDVRQITDVIQEDSRYKMLDRLDQERRLMLVQHLRFIHCPIRDHCPFFYNCVDSLIEEVLSDKSASNHKTPSGGGWKSSGSGSDRTLNLLIVGSEHLASDLLNDIRICTGSKGEYIYENQTYYLNYRIANGD----MEAFKAIDVYSSGLICVYSNQQSFETLKDNLERT--LLCNLELEDKFENLPIVLVYQPQ-DLKENEVEYLRNEGMRLSEMLHCDFIDHTQNHQKYVYDILNIVILSLKLTEMKSYEPYPSN---------HTDLRILCCIFCGDQYDIENIVQPLVEESTLVKAN---EHSIIVDVFIGDAKRRVEFILSSYHGTSQYR-DELIHGYIYFYSTKRRSSLANLSILAAQNAN-IPLQIIAVTESGGVNAFFNSDICQFLITEGNAVADRFKGSFMTFS--ADQYVKFAFYNPFLKTAWDNKYEVENLHVEESITLDSGEGTLENSVNQMPRPPPRHESYMLSNTLGTDGSGSENYEMAPTRSLNSLNEERDISLDEIYDDNEKPKHLHQKWLEDKSDGRRNMNKNLIWNNFSGSTHAYTTGRRHIDSNLNKIRPKGPSQTLKVGEAPSRNCPAMSSSTFTLPTQQPGKLNMKNFQLVSDAVAKMNFTGSGSGSGSGSGSGSTGLGLGLGSGSGCMGDSFLEPVDKDGKRYDHAQLDGEDEDSEELAEYEQIYENEDCTESDSCASSTERRVRQQNAYYKASKKPVAAKKQKKKKVAIPVQTPRVPPFGSYVSPPEIPLHYQRMAVGGSGPEKPEPCVPEFMKSDKSPEYSMVPELAGAGIFGAENLPEYNMNQAKCLKDFEKLEKRRIKEETARQRKLQEKEKEQEKKLKRKLKQNAKGLVESAEAQFGKLMITSEQGEIPIFLNKCVEFIEKEGLDSEGIYRVPGSRAHVDMLFQRFEEDTNTEIDALDIPVNAVATALKDFFSKRLPPLFSKDIIKELEEIAGSRGVGNSKLNVEVKTDRSCRLIALKSLLQKLPPINFAILKYIFQHFVHVSDNSKLNSMDSKNLAICWWPTLIPIDFTDMGHFEQLRPYLEDIVQTMIDQFPYLFCGKDAFVMV--------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :*::*******::*: **********::*. ** *: :* **** **.**:**********:: : ::*** ::::******:**.** ..: :::** **.: :*: *********.:***:*::::** **:*:*.:***:: :*:* **..:.*::**:.: : * ***:::.:** *:. : *:**.: : * ..: ::****: .:*:: .* *.* :**.:.: ***.* :: *::::*: : :: . : : : : ***. *. *: *..: :::*::*: * . .:: * :*:::*:::*:.:: .:*: .:. :: ** :: :: . * * . :..: :*: *. ::.* * .:*: :*. :***:*.* :.* :::*::: : .:*::: *::** **. *::**: .** :.* *.:: ::* * :::*. ** :*:*::*::* *:*:**:: * ::. . : :.: :* *:.*:.**: *::* :*. :*::*: *:: * :: * * * :*::*: .: .* . .:** ::* : **.:* *:** : :..** :.: * *: .: . :. . . * :**:.. :*:. : : : : .: . : :*: *: * * ::: **::* :*:: *:* *:* . . :: :* : * .:: . .:****: * :*** :.:: *:.*:::. : .: :::::* :**: :**::. : ***.: * ***:**** .**:**::*:. * : :: : **:*::*:*:* **:.: : *:***: :* .: ..* :: :: : : .:. *:. . ::* :*. .: : :: :.* .. * * * ... *. . . :.** * * :.: : : *.:.... .:*. : **: : :: :. .: . : . . . .. .*.: ** *. :: .* :: :.: : : .. . :.. .. *. .:* : :.* :. .. * .* * : * *::.* * * *. : .:.. : :.:: *:: . : * :* ... *. : . :. .. . : ::*.:: **:*::***::** *: :**:*** *.::. * : ::*::* . :: :::.***** *** **:. **:. .: ** * * *: *: .**.:::*: *:*: :::*:: *: :**:: * . * :.**:**:****: ** : . . :.:::::*:* ::* . : ", "identical_positions": 367, "similar_positions": 562, "identity": "22.42%" }, { "cls_id": "homologset.agr.RGD:1308508", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9DCA5-1", "uniprot_id": "BRX1_MOUSE", "id": "Q9DCA5-1", "name": "Ribosome biogenesis protein BRX1 homolog", "aln": "MAATKRKRRGGLEVQAKKPKRSSKDAGQPAKQADVAKEAEEENRDRIPGPVCKGKWKNKERILIFSSRGINFRTRHLMQDLRMLMPHSKADTKMDRKDKLFVINEVCEMKNCNKCIYFEAKKKQDLYMWLSNSP--HGPSAKFLVQNIHTLAELKMTGNCLKGSRPLLSFDPAFDDLPHYALLKEFLIQIFSTPRYHPKSQPFVDHVFTFTILDNRIWFRNFQIIE------------EDAALVEIGPRFVLNLIKIFQGSFGGPTLYENPHYQSPNMHRRVIRSITAAKYRERQQVKDVQKLRK-------KEPKTILPHDP---TADVFVIPAEEKPVEIQWVKPEPKVDLKARKRRIYKRHRKLQQKMSRGSAK----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4QQT6-1", "uniprot_id": "BRX1_RAT", "id": "Q4QQT6-1", "name": "Ribosome biogenesis protein BRX1 homolog", "aln": "MAATKRKRRGDLEVQAKKPKKNRKDAGQPAKQADVAKEAEEE-KDRIPGPVCKGKWKNKERILIFSSRGINFRTRHLMQDLRMLMPHSKADTKMDRKDKLFVINEVCEMKNCNKCIYFEAKKKQDLYMWLSNSP--HGPSAKFLVQNIHTLAELKMTGNCLKGSRPLLSFDPAFDDLPHYALLKEFLIQIFSTPRYHPKSQPFVDHVFTFTILDNRIWFRNFQIIE------------EDAALVEIGPRFVLNLIKIFQGSFGGPTLYENPHYQSPNMHRRVVRSITAAKYREKQQVKDVQKSRK-------KEPKTILPHDP---TADVFVTPAEEKPIEVQWVKPEPKVDLKARKRRIYKRHRKLQQKMSRGGAK----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8TDN6-1", "uniprot_id": "BRX1_HUMAN", "id": "Q8TDN6-1", "name": "Ribosome biogenesis protein BRX1 homolog", "aln": "MAATKRKRRGGFAVQAKKPKRNEIDAEPPAKRHATAEEVEEEERDRIPGPVCKGKWKNKERILIFSSRGINFRTRHLMQDLRMLMPHSKADTKMDRKDKLFVINEVCEMKNCNKCIYFEAKKKQDLYMWLSNSP--HGPSAKFLVQNIHTLAELKMTGNCLKGSRPLLSFDPAFDELPHYALLKELLIQIFSTPRYHPKSQPFVDHVFTFTILDNRIWFRNFQIIE------------EDAALVEIGPRFVLNLIKIFQGSFGGPTLYENPHYQSPNMHRRVIRSITAAKYREKQQVKDVQKLRK-------KEPKTLLPHDP---TADVFVTPAEEKPIEIQWVKPEPKVDLKARKKRIYKRQRKMKQRMDSGKTK----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VZE6-1", "uniprot_id": "BRX1_DROME", "id": "Q9VZE6-1", "name": "Ribosome biogenesis protein BRX1 homolog", "aln": "MGRKFQNKKKKAAPQLEIVPLDENPPLPPQRSSD----------DVVPKKARKEKWVNKQRVLVFSARGISHRDRHLMKDIKTLMPHHRPESKMERSKTLSVVNEMCEMKHCNKAMLFEGRRKRDLYMWISNTSGSTGPSAKFLIENIHTMAELKMTGNCLRGSRPLLSFDSKFDELPHLKLLKELFVQTYSVPNHHPKSQPFVDHVFTFTYLDKRIWFRNFQILS------------EDGGLSEVGPRYVMNPVKIFDGSFTGKTIWENPDYVSPSKQRQVLKKAAKDKYVNRVEQKVKHEATRPIRAYDGMDNDELFEDDDPVETAKILAAIAKKKKEEAAKQTPKSALTKKIKEKQLQAVKDVIERKKARTIKRVKKV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08235-1", "uniprot_id": "BRX1_YEAST", "id": "Q08235-1", "name": "Ribosome biogenesis protein BRX1", "aln": "MSSIYKALAG-----------KSKDNKSEKKQGN------------------VKQFMNKQRTLLISSRGVNYRHRHLIQDLSGLLPHSRKEPKLDTKKDLQQLNEIAELYNCNNVLFFEARKHQDLYLWLSKPP--NGPTIKFYIQNLHTMDELNFTGNCLKGSRPVLSFDQRFESSPHYQLIKELLVHNFGVPPNARKSKPFIDHVMSFSIVDDKIWVRTYEISHSTKNKEEYEDGEEDISLVEIGPRFVMTVILILEGSFGGPKIYENKQYVSPNVVRAQIKQQAAEEAKSRAEAAVERKIKR---------RENVLAADP-------------------------------LSNDALFK-------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. : . : :: **:* *::*:**:..* ***::*: *:** : :.*:: .. * :**:.*: :**: : **.::::***:*:*:.. **: ** ::*:**: **::*****:****:**** *:. ** *:**:::: :..* **:**:***::*: :*.:**.*.::* ** .* *:***:*:. : *::*** * .::** .* **. * ::. : : .: : :: : . :: * : : ", "identical_positions": 92, "similar_positions": 101, "identity": "24.15%" }, { "cls_id": "homologset.agr.RGD:1308509", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q69ZS7-1", "uniprot_id": "HBS1L_MOUSE", "id": "Q69ZS7-1", "name": "HBS1-like protein", "aln": "MARHRNVRGYNYDEDFE-DDDLYGQSVEDDYCISPSTAAQFIYSRR------------------DNP----EEEYGYEDLRESSNSLLNHQLSEIDQARLYSCLDHMREVLGDAVPDDILTEAILKHKFDVQKALSVVLEQDGVQPWKEKSERAVCAGQPSKGKSVISRSSQSESEIVPKVAKMTVSGKKQTMGFEVPGLTSEENGLSVRAPHKGPPGDDVSVASPNIPETGTPKSALPPPSLQTSEELGSTPTPVRKSGKLRQQIDVKAELEK-RQGGKQLLNLVVIGHVDAGKSTLMGHMLYLLGNVNKRTMHKYEQESKKAGKASFAYAWVLDETGEERERGVTMDVGMTKFETTTKVITLMDAPGHKDFIPNMITGAAQADVAVLVVDASRGEFEAGFETGGQTREHGLLVRSLGVTQLAVAVNKMDQVNWQQERFQEITGKLGHFLKQAGFKESDVAFIPTSGLSGENLTARSQSSDLTTWYKGMCLLEQID--SFKPPQRS----IDKPFRLCVSDVFKDQGSG---FCVTGKIEAGYIQTGDRLLAMPPNETCTAKGITLHDEP--------VDWAAAGDHVNLTLVGMDIIKINVGCIFCGPKEP-IKACTRFRARILVFNIEVPITKGFPVLLHYQTVSEPAVIKRLISVLNKSTGEVTKKKPKLLTKGQNALVELQTQRP---VALELYKDFKELGRFMLRYGGSTVAAGVVTEIKE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AXM7-1", "uniprot_id": "HBS1L_RAT", "id": "Q6AXM7-1", "name": "HBS1-like protein", "aln": "MARHRNVRGYNYDEDFE-DDDLYGQSVEDDYCISPSTAAQFIYSRR------------------DNP----EEEYGYEDLKESSNSLLNHQLSEIDQARLYSCLDHMREVLGDAVPDDILTEAILKHKFDVQKALSVVLEQDGVQTLKEKSERAVCAGQPSK---VISRSSQSESEIVPKVAKMTVSGKKQTMGFEVPGLPSEENGHNVRAPYKGPPGDDVSIASPNVPETGTPKSTAHPPSLQTSEELGCTPTPLRKSGKLRQQIDVKAGLEK-RQGGKQLLNLVVIGHVDAGKSTLMGHMLYLLGNVNKRTMHKYEQESKKAGKASFAYAWVLDETGEERERGVTMDVGMTKFETTTKVVTLMDAPGHKDFIPNMITGAAQADVAVLVVDASRGEFEAGFETGGQTREHGLLVRSLGVTQLAVAVNKMDQVNWQQERFQEITGKLGHFLKQAGFKESDVAFIPTSGLSGENLTSRSQSSDLTKWYKGLCLLEQID--SFKPPQRS----IDKPFRLCVSDVFKDQGSG---FCVTGKIEAGYVQTGDRLLAMPPNETCTAKGITLHDEP--------VDWAAAGDHVSLTLVGMDIIKINVGCIFCGPKEP-IKACTRFRARILIFNIEVPITKGFPVLLHYQTVSEPAVIKRLISVLNKSTGEVTKKKPKLLTKGQNALVELQTQRP---VALELYKDFKELGRFMLRYGGSTVAAGVVTEIKE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y450-1", "uniprot_id": "HBS1L_HUMAN", "id": "Q9Y450-1", "name": "HBS1-like protein", "aln": "MARHRNVRGYNYDEDFE-DDDLYGQSVEDDYCISPSTAAQFIYSRR------------------DKPSVEPVEEYDYEDLKESSNSVSNHQLSGFDQARLYSCLDHMREVLGDAVPDEILIEAVLKNKFDVQKALSGVLEQDRVQSLKDKNEATVSTGKIAKGKPVDSQTSRSESEIVPKVAKMTVSGKKQTMGFEVPGVSSEENGHSFHTPQKGPPIEDA-IASSDVLETAS-KSANPPHTIQASEEQSSTPAPVKKSGKLRQQIDVKAELEK-RQGGKQLLNLVVIGHVDAGKSTLMGHMLYLLGNINKRTMHKYEQESKKAGKASFAYAWVLDETGEERERGVTMDVGMTKFETTTKVITLMDAPGHKDFIPNMITGAAQADVAVLVVDASRGEFEAGFETGGQTREHGLLVRSLGVTQLAVAVNKMDQVNWQQERFQEITGKLGHFLKQAGFKESDVGFIPTSGLSGENLITRSQSSELTKWYKGLCLLEQID--SFKPPQRS----IDKPFRLCVSDVFKDQGSG---FCITGKIEAGYIQTGDRLLAMPPNETCTVKGITLHDEP--------VDWAAAGDHVSLTLVGMDIIKINVGCIFCGPKVP-IKACTRFRARILIFNIEIPITKGFPVLLHYQTVSEPAVIKRLISVLNKSTGEVTKKKPKFLTKGQNALVELQTQRP---IALELYKDFKELGRFMLRYGGSTIAAGVVTEIKE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W074-1", "uniprot_id": "HBS1_DROME", "id": "Q9W074-1", "name": "Protein HBS1", "aln": "MSRHRIVRTMDYNDEYDGYDDIYGHSVEDEHCISPTDAQQWLYDRARGQQSISAFISKNKDIQEEEADEDEDEDAAFAKARRDSESFQMPQLDEIEQAKLSSCVDEVRSVVGDAVSERRIVETSMKFDYDMQKILDEILNEETNKSAKP----------------AVNKMKAPAAPVLPKTVSKTVP--------------TPPPKISLKEPRRG-----FEIPSPKVPSSPVVSGRNTPVDISAGDDISRSSATVFKVSKEQAVRNARQLYEKERADQKSHIHMIVIGHVDAGKSTLMGHLLYDTGNVSQRVMHKHEQESKKLGKQSFMYAWVLDETGEERARGITMDVGQSRIETKTKIVTLLDAPGHKDFIPNMISGATQADVALLVVDATRGEFESGFELGGQTREHAILVRSLGVNQLGVVINKLDTVGWSQDRFTEIVTKLKSFLKLAGFKDSDVSFTPCSGLTGENLTKKAQEPALTNWYSGRHLLDVIE--NFKIPERA----IDRPLRMSVSDIYKGTGSG---FCISGRVETGVLCLNDKVLVGASREQAQVKSLTMNEFP--------QTCVFAGDQVSVTLPALDINNVTVGCIISDPQTP-IPVTTRFQARIIVFNVKVPITMGFPVLLHHQSLIEPAVVCKLTASIHKSTGEVVKKKPRCLGNNSCALVELETSRP---ICIERYADFKELGRVMLRVAGVTIAAGMVTKIR-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32769-1", "uniprot_id": "HBS1_YEAST", "id": "P32769-1", "name": "Elongation factor 1 alpha-like protein", "aln": "------MAYSDYSDGADDMPDFHDEGEFDDYLN--------------------------------------DDEYDLMNEVFPTLKAQLQDYQGWDNLSLK--------------------LALFDNNFDLESTLAELKKTLKKKKTPKK----------------PIAAANGSANVTQKLANISIS-----------------------------------QQRPNDRLPDWLDEEESEGERNGEEANDEKTVQRYYKTTVPTKPKKPHDISAFVKSALPHLSFVVLGHVDAGKSTLMGRLLYDLNIVNQSQLRKLQRESETMGKSSFKFAWIMDQTNEERERGVTVSICTSHFSTHRANFTIVDAPGHRDFVPNAIMGISQADMAILCVDCSTNAFESGFDLDGQTKEHMLLASSLGIHNLIIAMNKMDNVDWSQQRFEEIKSKLLPYLVDIGFFEDNINWVPISGFSGEGVYKIEYTDEVRQWYNGPNLMSTLENAAFKISKENEGINKDDPFLFSVLEIIPSKKTSNDLALVSGKLESGSIQPGESLTIYPSEQSCIVDKIQVGSQQGQSTNHEETDVAIKGDFVTLKLRKAYPEDIQNGDLAASVDYSSIHSAQCFVLELTTFDMNRPLLPGTPFILFIGVKEQPARIKRLISFIDKGN-TASKKKIRHLGSKQRAFVEIELIEVKRWIPLLTAHENDRLGRVVLRKDGRTIAAGKISEITQ", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :*.: : *::... *:: :: . : . : . :: * : :. .:*::. * : : : : : * .. ::. .. . . . : . ... . . . . : ::*:************::** . :.: ::* ::**:. ** ** :**::*:*.*** **:*:.: :::.* .*::*****:**:** * * :***:*:* **.: . **:**: .***:** :*. ***: :* :.:**:* *.*.*:** ** ** :* ** :.:: : * **::**.: : **.* *:. :: ** .:. * *: :.* :: . :. ::*::*:* : .: : ...: . .. : : . . ** *.:.* .: * : .. . . * * .: *::: *: * *.:*. :** : :* : :.*.. . *** : * . . *:**:: . : : : ..***.:** * *:*** :::* ", "identical_positions": 139, "similar_positions": 201, "identity": "19.12%" }, { "cls_id": "homologset.agr.RGD:1308510", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K046-1", "uniprot_id": "A0A0G2K046_RAT", "id": "A0A0G2K046-1", "name": "Myopalladin", "aln": "MQDDSIEASTSISQLLRESYLAETRHRGDNERSRAEPSSNPFHFSSP-GAAEGGG-PEDLPDLSAFLSQEELDESVNLARLAINHDPLERVDESQTRKRLSSDQ-----KPSFEPAFLQDSSRGLASSKDSPPETKRPQYSSETQSKKVFLNKAADFIEELSSLFKAHSSKRIRPRACKNHKSKTESPNKVVQENSPTFSDLTERRERTSVPIPIPADSRDNELNHAIEQREAKRREAELAAVEAAAGDSTPGSSPSSLYYEEPLGQPPRFTQKLRSREVPEGSRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGD------------------------------------------------------------------------------------------------PNKEEMNRIQKP----------------------------NEVSSPPTTSATIPPTV------------------QAQ-----PRVSTIQQCQSP--------------------------------------------------TNYLQGLNGKPIIAAPVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLAVRGNEDISD------------------------------------NETLHS------------------------------------------------------------------------------------------------DNSTTNPAATEQ---------------QPSP--------------------PNPQPPPEEQPPKP-------KLEGVLVNHNEPRSSSRIGLRVHFNLPEDDKDTE-------------------------------------------------ASSGCGMANTSQTRPDSFPERFNGQE---------ARISEPSSPVKEPPPVLAKPKLDSTQLQQLHNQVLLEQLQLHNTS---PSSPKESPFNTSILNS-APPTVTISSK----------------------------------------------------QVKSPAPQTFNLARPKHFFPASSTSTATVSP-------------------------SSSPVFTLSNTPQTIQRTVSKESLLMTHPSTQGR------SPGGLSIQNEPAP-----------------------------PSPAEP-----------------------------------------------------AVP-TVSYSITSGNQFQPHCVSPTPVSPT-GRIQNPVAFLSSVLPSLPSIPPTNAMGLPKSAPSVPPQGLMKKTTKTPQAVSDDYIRETKNSVILDLGKKVNFSD-----------------------------VRSHQQEYKISSFEQRLMNEIEFRLERTPVDESDDEIQHDEIPTGKCIAPIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRRDGDGTCSLHIESTHGDDDGNYTIMAANPQGRISCSGHLMVQGFPIRNRLSPAGQSHRGRSRMQERDKEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTYTCVATNKTGQNSFSLELTVVAKEVKKAPVILEKLQNSGVPEGHPVRLEGRVIGMPPPVFYWKKDNETIPFTRERISMHQDTTGYVCLLIQPAKKSDAGWYTLSAKNEAGIVSCTARLDIYAQWHQQIPTPISIR-PSGSRYGSLTSKGLDIFSAFSSMESTMMYSCTSRSVVESDEL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5DTJ9-1", "uniprot_id": "MYPN_MOUSE", "id": "Q5DTJ9-1", "name": "Myopalladin", "aln": "MQEDSIEASTSISQLLRESYLAETRHRGDNERSRAEPSSNPFHFSGP-GAAEGGG-PEDLPDLSAFLSQEELDESVNLARLAINHDPLERVDEAQARKRLSSDQTKHASKPSFEPAFHQDSSRGPASPKDSPPETKRPQYSSETQSKKVFLNKAADFIEELSSLFKAHSSKRIRPRACKNHKSKTESQNKVLQENSPTFSDLTERRERASVPIPIPADSRDNELNHAIEQREAKRREAELAAGEAAAGDSTPGSSPSSLYYEEPLGQPPRFTQKLRSREVPEGSRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGD------------------------------------------------------------------------------------------------PNKEEMNRIQKP----------------------------NEVSSPPTTSAAIPPAA------------------EAQPLAAQPRVSTVQQCQSP--------------------------------------------------TNYLQGLNGKPIIAAPVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEPEEICTLVIAEVFSEDSGCFTCTASNKYGTVSSIAQLDVRGNEDISD------------------------------------NGALHS------------------------------------------------------------------------------------------------ANSTTNPAVAEH---------------QPSP--------------------LNPQPLSEEQPPKP-------KLEGVLVNHNEPRSSSRIGLRVHFNLPEDDKDME-------------------------------------------------ASSGSGAANTSQTRPNSFPERFNGQE---------ARIPEPSSPIKEPPPVLAKPKLDSTQLQQLHNQVLLEQQQLQNTS---PSSPKES-LHMSALNS-APPAVTISSK----------------------------------------------------QVKGPAPQMFNLARPKHFFPASSTSTATVSP-------------------------SSSPVFTLSNTPQTIQRTVSKESLLMAHPSTQGR------SPGGLSIQNEPAP-----------------------------PSPAEP-----------------------------------------------------AAPPTAAYSIPSGNQFQPHCVSPTPVSPT-GRIQNPVAFLSSVLPSLPSIPPTNAMGLPKSAPSVPSQGLMKKTTKAPQAVSDDYIRETKNSVILDLGKKVNFGD-----------------------------VRSHQQEYKISSFEQRLMNEIEFRLERTPVDESDDEIEHDEIPTGKCIAPIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCSLHIESTHGDDDGNYTIMAANPQGRISCSGHLMVQGLPIRSRLSPA-LSHRGRSRMQERDKEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTYTCVATNKTGQNSFSLELTVVAKEVKKAPVILEKLQNSGVPEGHPVRLEGRVIGMPPPVFYWKKDNETIPFTRERISMHQDTTGYVCLLIQPAKKSDAGWYTLSAKNEAGIVSCTARLDIYAQWHQQIPTPISIR-PSGSRYGSLTSKGLDIFSAFSSVESTMLYSCTSRSVVESDEL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86TC9-1", "uniprot_id": "MYPN_HUMAN", "id": "Q86TC9-1", "name": "Myopalladin", "aln": "MQDDSIEASTSISQLLRESYLAETRHRGNNERSRAEPSSNPCHFGSPSGAAEGGGGQDDLPDLSAFLSQEELDESVNLARLAINYDPLEKADETQARKRLSPDQMKHSPNLSFEPNFCQDNPRSPTSSKESPQEAKRPQYCSETQSKKVFLNKAADFIEELSSLFKSHSSKRIRPRACKNHKSKLESQNKVMQENSSSFSDLSERRERSSVPIPIPADTRDNEVNHALEQQEAKRREAEQAASEAAGGDTTPGSSPSSLYYEEPLGQPPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGD------------------------------------------------------------------------------------------------PNKEEMNRIQKP----------------------------NEVSSPPTTSAVIPPAVP-----------------QAQHLVAQPRVATIQQCQSP--------------------------------------------------TNYLQGLDGKPIIAAPVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDLSN------------------------------------NGSLHS------------------------------------------------------------------------------------------------ANSTTNLAAIEP---------------QPSP--------------------PHSEPPSVEQPPKP-------KLEGVLVNHNEPRSSSRIGLRVHFNLPEDDKGSE-------------------------------------------------ASSEAGVVTTRQTRPDSFQERFNGQA---------TKTPEPSSPVKEPPPVLAKPKLDSTQLQQLHNQVLLEQHQLQNPP---PSSPKEFPFSMTVLNSNAPPAVTTSSK----------------------------------------------------QVKAPSSQTFSLARPKYFFPSTNTTAATVAP-------------------------SSSPVFTLSSTPQTIQRTVSKESLLVSHPSVQTK------SPGGLSIQNEPLP-----------------------------PGPTEP-----------------------------------------------------TPP-PFTFSIPSGNQFQPRCVSPIPVSPT-SRIQNPVAFLSSVLPSLPAIPPTNAMGLPRSAPSMPSQGLAKKNTKSPQPVNDDNIRETKNAVIRDLGKKITFSD-----------------------------VRPNQQEYKISSFEQRLMNEIEFRLERTPVDESDDEIQHDEIPTGKCIAPIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQERDKEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKEVKKAPVILEKLQNCGVPEGHPVRLECRVIGMPPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCTARLDIYAQWHHQIPPPMSVR-PSGSRYGSLTSKGLDIFSAFSSMESTMVYSCSSRSVVESDEL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A9B6-1", "uniprot_id": "A0AB13A9B6_DANRE", "id": "A0AB13A9B6-1", "name": "Myopalladin", "aln": "MQENSMDQPTSLSQLLRESYLAESRAHHRHGESTDPPRRLVYGTLKEKNQESCAKLDTPIPDLSAFLNQEELDKSVDLACKAISDDPQER-DQKSAKPQIESTP----------KKVQENTHR--TNVADFKRAQRTAPYGMETQSKKEFLNKAADFIEELSSLFKANSSKRIRPRSCKAHRSRYQNKP---QPDGASFSVNAEDRERP--------------VIQPMEETMEDTREPEPTAAGTVCESTDMVQSES---LEEPECEPPQFIQKLKSREVAEGSKVQLDCIIRGKPAPEVRWFCEGKELENSPDIQIITDGERHSLIIAEAFEEDTGRYSCFASNFYGTDSTSAEIYIEGASSSDSDGEQHYPAQLHKRSQPKPAVVSVESSSSLEDTTSTVTITCAEAPAPEAVPLTKLTPDQPLQPEETEPQSFEIFSSATPVEHPIVPFPEPVIEPALPVLEPVKEPTISVLEPTIEPTISVLEPTISVLESVIEPAISVLEPTISLAEPTISVLEPTIEPTVSVLEPTISLLGPVIEPAILAVEPTISVLESTISVREPVIEPTIPVLEPPTPILEVEPSPPPSSQSIPDLLLTSQQSISESLNGSSSYVQSFDVRPMMAAPVFTKNLQDVLALESQLVVLECRVKGVPSPKVDWYREGMLIDDSPDFRILQKKPRSMAESEEICTLVIAEVFPEDSGTFTCTASNKYGTVSSTANLSVKGHNNNTTNAKKTSMLTVESSLPKVPTTDLISTTLTRKPDLPLVNNKLHSSMICLDPLNSGFKQSYPLDGGTFRSDSLNTSTLRHDLSTSLPSLNPISIGKYSSDTLRSRLPQTDPLGFSAFSPNSDLTHKPLSSSTPHFDSGGSGFNSSTDVTQSPPNGLASSITLSTDTCLEPSPNASKSILSPCITSPPLLNSNNHQERPPVKPLPDPPTSCLKTRPEGVLGNHNESRSSSRVGLRVTFKLPEDEEEEEKGLSSKGPPPVLAKPKLDPSQLQILHNQVLLEQRQDNVSPSLESQHLDETSCEALPITPTQLSVNPFPSAFRPTPNVMDSGPFPQLIPASIPPPPAGPAPILKATPASQFSISLPNSMPLPQLTPSTTLNILPSSPQQNMVPTTFMNTDAPITVPSTSIPQSIVMHKAVPISPILAPMPNVIPTTPITQSAGAPNIPQSNVGPSTHFPQLIMVPSTQPNLSHLANVSPITPSTHTSQINSNPNLQMSAPKMQALTTPDVALVNNTKLNSTSVTYPSMTPHSPSVVYPSLSNITSPPMGRNRPTPSPMSPPPLTDTQLPLPGIIPISTQSFSYTRPKEFIAAQALSPIRGPSPTESPVPMLHELAAQIFPKTTRDLTSPINQLPPFPRKFPTRVLEGPSSPPYVSSPPLNPPGLVNSVFSFRTQSPPQASSPTSSSSSPSPIQNPVAFLSSVLPSLPTSPPTNAMGLPMRAPPGP-QSALKRSQRGSRLISDDEIRDSKELLLQDIEKKLQFRDEPLRFGQQKPMCFVGEMRHPLGPNIPTATVINYDEEYKVSSFEQRLMSEIEFRLERTPVEESDDEVQHDEIPTGKCIAPIFDKKLKHFRAVEGIPVTFTCKVVGIPIPKVYWFKDGKQILKKNEHYRKIREGDGTCSLHIETVTNDDDGNYTVMAANPQGRISCSGHLIVQTGPVRNR--PVVHSQRVRARVQEVEGEPTQERFFRPHFLQAPGDMLAHEGRLCRLDCKVSGLPHPEIMWLLNGKPIYPDVTHRMLVRENGIHSLVIDPLTQADDGTYTCIASNKAGQSSFCLQLKVVEKEMKAAPRFVEKLQNTGIAEGAAVRLECRVAGMPQPVIYWKKDNDTIPHSRDRVSMHQDTTGYVCLLIQPTRKEDAGWYTVSAKNEAGIISCTARLDIYAQWHQHVHPPMKKSSLTGSRYAALTGQGLDIKSAFPMSESGPHVLFRER---ESDEL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**::*:: .**:***********:* : : .* * . . . :*******.*****:**:** **. ** *: *: .:: ::.. . ::. * :. : : . * ****** *****************::********:** *:*: :. * :..:** :* ***. : :.:*: . **.* :* :. .: .* * *** :**:* ***:****.**::******: * *.*:***:************:*: *: *** ******************:**************.*****:*: * ** : :* :* . .* :.: *: :. * ::.::. * :.*:*.:: :*::******* **:: * *.****:******.*****:***** **:*****************.************.**** ************** *:* *:*::: : * *** **:*: : :*** : : . : *.* : **** ****.*****:**** *:****:: * :*. . .. * :.* . *. . . .* *. : *.. * .* *.: * * .. ****:: . : :*: ** :*. :* * .. .: **. . : *:: *: . * .*:.* * **:: . . .. * : : * : : ** *: : * * *.*:*. * :. .* *:. ** . *.: . ****************: ********* **. * *. *:. : .: :.** **::*: :: *: **: * * * ::***:********.***********:*****::****************:*****..** *******:****:************ *:*** : *:**********:. .*******:***************:** *:*.* .. *:* *:*:** : ** ****************:***************** **: *****:*: **.:*:*****.*:***:****** * ***.*:*:**:**.**.*:*.** **:* ** ::***** *:.** .**** ** *** **:******:*** :*:*:*********.******::*.******:********:*************::: .*:. :****.:**.:**** ***. ** .* *****", "identical_positions": 692, "similar_positions": 296, "identity": "35.62%" }, { "cls_id": "homologset.agr.RGD:1308511", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4AAT1-1", "uniprot_id": "D4AAT1_RAT", "id": "D4AAT1-1", "name": "", "aln": "MLRDPTATRWPPLLLLLLQLPPPPLVCGAPARPGTRTQASELVVPTRLPSSASELAFHLSAFGQSFVLRLAPDASFLAPEFKIERLGGS-------SAAAGGEP-----------GLRGCFFSGTVNGERESLAAMSLCGGLSGSFLLAGEEFTIQPQG----AGDSLDQPHRLQRWGPGQRREDPGLAAAEVFPLPQGLEWEVEMGDGQGQRRRDNEEDRERDKEGLRKETEDSREVTPPFGSKTRSKRFVSEARFVEILLVADASMAAFYGTDLQNHILTVMSMAARIYKHPSIRNSINLVVVKVLIVEEEGWGPEVSDNGGLTLRNFCSWQRRFNKPSDRHPEHYDTAILFTRQNFCRKGEQCDTLGMADVGTICDPNKSCSVIKDEGLQAAYTLAHELGHVLSMPHDDSKPCVRLFGPMGKYHMMAPFFIHVNKTLPWSPCSAVYLTELLDDGHGDCLLDAPTSVLPLPTGLPGHSTLYELDQQCKQIFGPDFRHCPNTSVEDICVQLWCRHRDSDEPICHTKNGSLLWADGTPCGPGHLCLDGSCVL--REEVENPKAVVDGDWGPWGPWGQCSRTCGGGIQFSNRECDNPAPQNGGRFCLGERVKYQSCKTEECPPN-GKSFREQQCEKYNAYNHTDLDGNFLQWVPKYSGVSPRDRCKLFCRARGRSEFKVFETKVIDGTLCGPDTLAICVRGQCVKAGCDHVVNSPKKLDKCGVCGGKGTACRKVSGSFTPFSYGYNDIVTIPAGATNIDVKQRSHPGVQNDGSYLALKTANGQYLLNGNLAISAIEQDILMKGTILKYSGSMATLERLQSFQALPEPLTVQLLTVSGEVFPPKVKYTFFVPNDTDFNVQSSKERASTNIIQSLPYAEWVLGDWSECPSTCGGGWQRRTVECRDPSGQASDTCDEALKPEDAKPCGSQPCLL-------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P57110-1", "uniprot_id": "ATS8_MOUSE", "id": "P57110-1", "name": "A disintegrin and metalloproteinase with thrombospondin motifs 8", "aln": "MLRDPTTTGWPPLLLLLLQLPPPPLVCGAPAGPGTGAQASELVVPTRLPGSASELAFHLSAFGQGFVLRLAPDASFLAPEFKIERLGGS-------SAAAGGEP-----------GLRGCFFSGTVNGERESLAAMSCVAGWSGSFLLAGEEFTIQPQG----AGDSLDQPHRLQRWGPGQRREDPGLAAAEVFPLPQGLEWEVEMGNGQGQERSDNEEDRKQDKEGLLKETEDSRKVPPPFGSKTRSKRFVSEARFVETLLVADASMAAFYGTDLQNHILTVMSMAARIYKHPSIRNSVNLVVVKVLIVEKERWGPEVSDNGGLTLRNFCSWQRRFNKPSDRHPEHYDTAILFTRQNFCGKGEQCDTLGMADVGTICDPDKSCSVIKDEGLQAAYTLAHELGHVLSMPHDDSKPCVRLFGPMGKYHMMAPFFIHVNKTLPWSPCSAVYLTELLDDGHGDCLLDAPTSVLPLPTGLPGHSTLYELDQQCKQIFGPDFRHCPNTSVEDICVQLCARHRDSDEPICHTKNGSLLWADGTPCGPGHLCLDGSCVL--KEDVENPKAVVDGDWGPWRPWGQCSRTCGGGIQFSNRECDNPMPQNGGRFCLGERVKYQSCNTEECPPN-GKSFREQQCEKYNAYNHTDLDGNFLQWVPKYSGVSPRDRCKLFCRARGRSEFKVFEAKVIDGTLCGPDTLSICVRGQCVKAGCDHVVNSPKKLDKCGVCGGKGTACRKISGSFTPFSYGYNDIVTIPAGATNIDVKQRSHPGVRNDGSYLALKTANGQYLLNGNLAISAIEQDILVKGTILKYSGSMATLERLQSFQALPEPLTVQLLTVSGEVFPPKVRYTFFVPNDMDFSVQNSKERATTNIIQSLPSAEWVLGDWSECPSTCRGSWQRRTVECRDPSGQASDTCDEALKPEDAKPCGSQPCPL-------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UP79-1", "uniprot_id": "ATS8_HUMAN", "id": "Q9UP79-1", "name": "A disintegrin and metalloproteinase with thrombospondin motifs 8", "aln": "MLPAPAAPRWPPLLLLLLLLLP--LARGAPARPAAGGQASELVVPTRLPGSAGELALHLSAFGKGFVLRLAPDDSFLAPEFKIERLGGS-------GRATGGER-----------GLRGCFFSGTVNGEPESLAAVSLCRGLSGSFLLDGEEFTIQPQG----AGGSLAQPHRLQRWGPAGAR-----------PLPRGPEWEVETGEGQRQERGDHQEDSE--EESQEEEAEGASEPPPPLGATSRTKRFVSEARFVETLLVADASMAAFYGADLQNHILTLMSVAARIYKHPSIKNSINLMVVKVLIVEDEKWGPEVSDNGGLTLRNFCNWQRRFNQPSDRHPEHYDTAILLTRQNFCGQEGLCDTLGVADIGTICDPNKSCSVIEDEGLQAAHTLAHELGHVLSMPHDDSKPCTRLFGPMGKHHVMAPLFVHLNQTLPWSPCSAMYLTELLDGGHGDCLLDAPAAALPLPTGLPGRMALYQLDQQCRQIFGPDFRHCPNTSAQDVCAQLWC-HTDGAEPLCHTKNGSLPWADGTPCGPGHLCSEGSCLP--EEEVERPKPVADGGWAPWGPWGECSRTCGGGVQFSHRECKDPEPQNGGRYCLGRRAKYQSCHTEECPPD-GKSFREQQCEKYNAYNYTDMDGNLLQWVPKYAGVSPRDRCKLFCRARGRSEFKVFEAKVIDGTLCGPETLAICVRGQCVKAGCDHVVDSPRKLDKCGVCGGKGNSCRKVSGSLTPTNYGYNDIVTIPAGATNIDVKQRSHPGVQNDGNYLALKTADGQYLLNGNLAISAIEQDILVKGTILKYSGSIATLERLQSFRPLPEPLTVQLLTVPGEVFPPKVKYTFFVPNDVDFSMQSSKERATTNIIQPLLHAQWVLGDWSECSSTCGAGWQRRTVECRDPSGQASATCNKALKPEDAKPCESQLCPL-------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QEM5-1", "uniprot_id": "A0A8M9QEM5_DANRE", "id": "A0A8M9QEM5-1", "name": "", "aln": "------MVSTIVYVFFLVNLMSQFALCELNEEEET-VLVNRTFRKGLFWRSEERQHFKLSAFGHLFLLDLSPDSKFVSPVLNVQRIKAKNLRSVLDASRSGGALRDATLYPDSGADLRDCFYTGTVNSEKESVVAVSLCHGIHGTFITQGVEYFIHPKASVQTTGKHFPQVHVIKRRAVSNSR-------------TASLVFDQMKVDSLVKESKLNS-----------SEDEDS--------NMRRAKRFVSAARYIETLVVADASMTRFYGDEIKHYLLTVMAMAAQVFVHPSLKNAVSLVVVKMVVVEDEEVGPELSSNGGVALRNFCMWQQLFNPGSQRHPEHYDTAILFTREDICGYKD-CDTLGVADVGTMCDPKRSCSVIEDNGLQAAFTVSHELGHVLSMPHDDSKNCEKWFGHLYG-HTMAPFFVHLNKTLPWSPCSALYITEFFDNGHGDCLLDPPEMTIPLAAELPGHT--FGLDQQCQQAFGNKYTHCSNAPADQTCVQLWC--REEGKIQCTTRNGSLHWADGTPCGEDRRCREGLCLSSAMEEAGEQKVPVNGGWGEWGPWGPCSRTCGGGVEFSHRECTSPVPQNGGLYCVGQRVKYQSCNTQTCPEDHGKSFREEQCEKYNSDRYMDIKGNIKQWIPKYSGVSPRDRCKLVCRAKGSNEFKVFEAKVVDGTTCGPDTTSICVQGQCIKAGCDQVIGSNEKLDKCSVCGGDGTTCRKISGSLNKATIGYIDIVTIPAGATNIDIKQRSHRGIPHDGNYLAVKAQDGTYILNGNFSVSMAEQDVPVPGAMLRYSGSSTTLERLLSFHRLQEPITIQLLSTAGDISPPRIKYTFFLPRDVPFSKPGTESRISTHVISPFGGFDWVLGEWSECSKSCGAGWSRRSVECRDGEGSLSYLCDADLRPADIRPCGDLPCPMWQMGPWSACSRTCGPGERHRTVVCLDYAGKVLEPQKCNPDKRPEVAVGDCFYQDC", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :::*: * . : ... . : * . ::*****: *:* *:** .*::* ::::*: .. . :** .**.**::****.* **:.*:* * *:*: * *: *:*:. :* : * * ::* . . * . . :: :. :. :. .* *.: *:***** **::* *:******: *** ::::::**:*::**::: ***::*::.*:***:::**.* ***:*.***::***** **: ** *:***********:**:::* *****:**:**:***.:*****:*:*****.*::*************** * : ** : * ***:*:*:*:*********:*:**::*.********.* .:**.: ***: : *****:* ** .: **.*:..:: *.** . : : * *:**** ******** .: * :* *: *:. . * .:*.*. * *** ********::**:*** .* ***** :*:*.*.*****:*: ** : ******:******: .: *:.**: **:***:**********.***:* .******:**:*** ***:* :***:***:*****:*:.* .*****.****.*.:***:***:. . ** *************:***** *: :**.***:*: :* *:****:::* ***: : *::*:**** :***** **: * **:*:***:..*:: **:::****:*.* *. .::.* :*::*..: :****:****..:* ..*.**:***** .*. * *: *:* * :** . * : ", "identical_positions": 430, "similar_positions": 250, "identity": "43.65%" }, { "cls_id": "homologset.agr.RGD:1308512", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LUC8-1", "uniprot_id": "A0ABK0LUC8_RAT", "id": "A0ABK0LUC8-1", "name": "", "aln": "MKRRRWRESGGGGGGAKLRARLSVKPNVRPGVGTRGSAAPNPQRGPEAPRPPEPATGSAPKPAEPTDVPAVDSGGAEPQEQAPGSSNNEKTGDGSNVEESSTLPSAASQRRKRVSGTSSLGQPPVSAPSQSRPLSTVNHDAPQPNPTPAKEKQPCSDRYRIYKARKLREMLKEELRKEKKQWKNKFATNESQRPPDRSKMTMRDFIYYLPDSNPMTSSVEQEKKCEKSLAPTPTRE-QENQSTQDANDNEDVEEEVDDGPLLVPRVKVAEDGSIILDEESLTVEVLRTKGPCVVEENDPIFERGSTTTYSSFRKNYYSKPWSNKETDMFFLAISMVGTDFSMIGQLFPHRARIEIKNKFKREEKTNGWRIDKAFQEKRPFDFDFFAHLLQKVLAEEEKRKQKSTKCQNVKEKAP-KPRKNAKAKTVNREEVNDDPDESVNSDTADPERPQKDARTVREEQLPSSSAQHLHLAVLEQEQEQEQSQDKRRRNQGKANKREATTVLESVLDHSSPPAAEIHKSTCPSEE---NENECNKEQTPSFTQNTEDIAGLASCEETLMRMDPSPSTCNHQDIMPLASESSEPCAADLPVSEPGGAVSGDVNNAESGCAGAGSADLKTKSPETEQTDSVKPKSRSRLQRPKPNLSRPVGKKSVVSQDRQDGSNKDSPSETAATKNHMEKERVTESENFVTENTERESPSAGTVSDLSEKSSAQEDSQTKVLRPTRLMRSRMQRPKPNVVKAAERKQILTSQEKVGSHVEKIEDDSCVV--VPPQMGNESHKNLQCEGAASEPEQKDPVESLQSEQPRALSECPSIQEDNKGNKLKQAPIVRTRFQKPKPNTGR-RRRRRRSSKEGIPVDMPVSGDLTATREEIPRPDTSPREEVPSVP----------------LAP----LTATASTMELESGVKDSSRNDTASNVKMPEMADVTMEIDTGLETTG-RDTCPGEMEAEMIDIPMETEASLKASLNETPPMEKMPELIDNTGEICTNLGETARKEIFLQENGSKEVSPVSEPETGLQETG----------------------------------------------------------------------------------------------------------KKLAVKESTSDMMDGTEEREADSEETERQE-ISAPVKEAEEAKARGEVDSPLEEIGGETSQQA-----IAAGAPVEQSASEEDLGDS--------------------------AGVEEVEVESTVG-GKELKLKDAGEGHVSLMVVVSGEKTAIEETIGHLKEKERESSVPWERRSGEIDVGEEMVADLEKTEKVDVSPRDSEPEEQ-TSGQPEAEVIPSRS-DGSTGPPQDRENIS-NKISVIPTLLEEKETTDKEVSSHG---ESSSQNS-GHHVADQGTQLLDVQEQFSDTNLSKPLPQEQKPLQVKPAPFLRSRFKKPKPNLSRAALKRATLEAEHCVPGKKPEAYKMETVVLQQDRDQAASFSSPHNVPSLMASRENEKSGHEEEEEAVVLPCTQIEKDPSPPNSCEPKEDSQLTQNQEDSLVSPIGTPTVNMVPQETKPNVVQTTLPVRGRLQRPRPNVQKARQRQTVEKGKAEGITKNEGPELQKDEAKTCLTVANSSGVESEVAVEVSSRVSEFKVNESQGHVVPVENLSINKTSVLREQIRHENKPYVPSPALLIRRRFQKAKPNLGGARHKDEQPGVEKGPTSENTALTTEDHLLQKGDCDTQLSVQAREKTEMPLEVSMRKDCVHSEESGSDRNDAQLK-AGPSGGAREEIAQEPTFSSSLEEQSLSKQISR--PQLLKESSYSKTVPPRRTTVPSASECEIDHSGKRAHRKMKASVTKARGSKRIRGKTAKKEPRASKSVLVTLRASQKDDEDDAEDFESDYEEETCHLAPEELNKAPVFVPVGLRSPEPVSAQIEETMEELEITMDGADLGCLTVVDHQLSHVDIAARDEQPEKAVYPSSFEVVIGEQPQEEPGPGDGSTEAAITLLTMGDIVLQSEIIPGQGDVGVCVFPDDHSKDKNHVPFIPDNVNQKTVHDYQEVCSPVISMSHVSFEDNKIVLEEQSIRE-AAVLGEAMEEPLSTRDTACTMSTPLRMESMLVTPKAGSERILEISEPDGHQEVASLCMTKGTEVEIQRETEENDSTAVELDDKSLEPVPAAETKEQEQLLCVHGVEGARVSQEAILPARTEEHEDDLQGLQTLGAA-VASSEIGQHTLESGQSLGDSVAEEALRESPEGSVVPMLHVPESVPSNIPEAQHENIS-PQDDTVNLFANVQQDGEDEQAFILTLVEIPTNTTEGFTDASMHLMPSSLLPAPILVRSGNAVERVDLSGSLQASSVVQDVTCSSPSRSGDSEKPPAIVELTSRKRFCCSPDESIHVPPAKKSSIAPGIDYQNCTSGVCSEELN-VFEKTEESCMGQGIFPTSESTHATSKPQKEHSEQTSQNTGSSGSLGEIKDACVENTMTELPQSE-VVSDKEEKTDPASNSKQRDSVTSSSKPPLTRPGRRPLGFLSLICPKNSLESDEVTQTHSKKRLKPHIPVSRRNLKKPNPLHASQKKNQESSDPLPPPSVTETVSDNTGSSESSAAEVSSDQPLVEEEKCKNGPKGASEEEVTTVSEFVFSDIFIEVDETE---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q571C7-1", "uniprot_id": "BDP1_MOUSE", "id": "Q571C7-1", "name": "Transcription factor TFIIIB component B'' homolog", "aln": "MFRR---------------ARLSVKPNVRPGVGTRGSAAPNPQRGPEAPRPPEPATESAPKPAEPTDVPAVDSGGAEPQEQAPGSSD-EKTGDKNNAAESSTLSSASSQRRKRVSSTSSLVQPSGSAPSQSRPLSTVDHDAPQPNPTPAKEKQPCSDRYRIYKARKLREMLKEELRKEKKQWKNKFSTNESQRPPDRSKMTMRDFIYYLPDNNPMTSSVEQEKKPEKSLAPTPTRDRQENQSTQDANDNEDVEEEVDDGPLLVPRVKVAEDGSIILDEESLTVEVLRTKGPCVVEENDPIFERGSTTTYSSFRKNYYSKPWSNKETDMFFLAISMVGTDFSMIGQLFPHRARIEIKNKFKREEKTNGWRIDKAFQEKRPFDFDFFAHLLQKVLAEEEKRKQKSTKCQSLKEKAS-KPRKNLKAKTVTSEEVNDDPDESVNSNISDPERSQNDAETVNEEESPSSSGQHLEQAMLEQDQNQEK---KRRRNQGEANKQEATNLLERVLVHSSPPAAEIHKNTCPSEE---NESECNKEQIPSLTQNIDDIAGLAPSEETEMRMDPIPSTCNQQDIMPLARESSESCAVALPVWEPGNTASADMAHAESSCSEGRGADLKTAAPETEQTENVKPKSRSRLQRPKPNLARAVGKKSAVSQDRQDERNKNSPSETAAEKNHMEKETMNESETSVAKNTDGESPGAKTVSDLSEKSCVQQDSQAKVLRPTRLMRSRMQRPKPNVVKAAERKEILTSQEKFGAHVEKSEDESCVV--IPPQTENESHKNLQCEDTVSEPGRKDPFENIQPDQPQVLSDCPSIHEGNKENKRKQVPVLRTRFQKPKPNTGR-RRRR-ISSKEGIPEETPISGEIPATWEEIPSLDTSLREEVLSVP----------------LAP----LTATASTKDSESDVKDSGRNDTASNAEMSEMTDVTMEMETGLETIG-RDTCPGEMGAEMIDIPMETEAGLKASLNETSCMEKVPELIDTTGEICTNLGETGRKEVFLQENGPKEVGPVSEPETGLQETG----------------------------------------------------------------------------------------------------------KDLAMKESTPDTTDSTEEREAYSEETERQEKISALIKDAEEAKARGEMETPLEEIGGGTSQRG-----KAAGAPVEQSASEEEPQGS--------------------------ACREEVAVESSTAEGKELNLRETGEDDVSSMVVVLGEKTDIEETNGDPKETERESSVSWERGSGEIQVGEEMVEDLGKPEKIDVAPREREPEEH-SSGQPEADVILSSS-DGSTGSPQDKVNIS-SKISVMPTLVEEKETTDKDISSHLGHVESCSQNL-GRHETDQGMPLPDALERFSDTNLSKPLPQEQQPLQVKPAPFLRSRFKKPKPNLSRAALKRATIEAEHCVPGKKSEACKVEAAMLQQDSDQAA-LSPQHNVPSLMASRENDKSGHEEEEEAAILPCTQTEKDASPPNSSEPKEGSQLTPNQENGLLVPIGTPMMNTVTQETRQNVVQTTLPVRGRLQRPRPNVQKARQRQIVEKGEARDIAKNEGPELQKDETRTCLTVANSSHIESGVAVDMSSRVSECQVSESQGHADPVENLSVNKASVVHEQMRHENKPYVPSPALLIRRRFQKAKPNLGGARRKDEQPGVEKGRTDESTALTAEDHLLQKEDCDTQLSLQAREKADMPLEVSVRKECIHSEESGSDRNDAQPN-AGPSEGSRDETAKEQPTSLGLEEQSLSKQIRSSCPQLWKESSYPKTVSSRRTPLSSASECEIEHSWKRTQRKTKPNLTKGRGSKRIRGKTAKKEPRASKSVLVTLRASQKEDEDDAEDFDSDYEEETYHLAPEELSKAPVFVPVGLRSPEPVSAQIEETMEELEITMDVADM---TVVEHQLSHMDTTAQAVQAEKAVYPPSFEMDVGEQTQEEPGPSDGSTEAAITLLTMGDIVLQSEIIPGQGDVGVCVFPDVHSEDKSHAPFSPDNVNQKVVHDYPEVCSPVISTSHASFEENRIVSKEQSNRD-AAVEEEAVEETLPTRNTTSTMSTHLRMESMVVTPELNSEKTLEISESHGHQEVASFCITKETEVEIQRETEGDDSKAVELEDKSHAPVTAAETKEEEQSQCVGDVEGASVSQEAILPARIEDHEETLQEVQESGTA-VASSEIGQQTLDSGQSFGESAAKEALKETPKGSDVPVLHGPESVPSHIPEAQQENTG-PQAVTVNPFADGQQDGEDEQAFILTLVEIPTHATEGFTDAAMQLMPSSLLPAPILVRSGNAAERGDLSGSLQTSLVVQDAPSLSPSRSGSSEKPPANLDLTSRKRFCCSPDESIHVPPAKKSSLVPGIDYQECTSEVCSEELN-VFEKTAESCMGQGIFPTSESTHATSKPQKEHSEPT--DTGSSGSLDEIKDACVEN-MAQLPQSE-IVSDKEEKTEPASNSEQRDIVTSSSKPPLTRPGRRPLGFLSLLCPKNSLESDEVTQTHSKKRLKPQIPVSRRNLRKPNLHNTSQKKNQDSSAPPPSPSVTAPLSGTAGSPESSAAQVSSDQPLLKEE-CKNGPKGAPEEEVTPVSEFVFSDIFIEVDETL---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6H8Y1-1", "uniprot_id": "BDP1_HUMAN", "id": "A6H8Y1-1", "name": "Transcription factor TFIIIB component B'' homolog", "aln": "MFRR---------------ARLSVKPNVRPGVGARGSTASNPQRGRESPRPPDPATDSASKPAEPTDVPTVDFGGAEPQEKAPRSST-EKTGGDNDVEESSRSSSTVSQRRKRISSTSSLVKSSVSVPSESHPLSTINQEAPQPTATSTKEKQPCSDRYRIYKAQKLREMLKEELRKEKKQWKNKYAINESQRPPDRSKMTMRDFIYYLPDNNPMTSSLEQEKKTEKPSTPVQTRE-QEGKSTPNAEDNE-MEEETDDGPLLVPRVKVAEDGSIILDEESLTVEVLRTKGPCVVEENDPIFERGSTTTYSSFRKNYYSKPWSNKETDMFFLAISMVGTDFSMIGQLFPHRARIEIKNKFKREEKTNGWRIDKAFQEKRPFDFDFFAHLLQKVLAEEEKRKQKSVKNHSLKEKKSTKPRKNVKVKKVACEGVNNDPDESMSSRISDTERSQKDAQTVEEESLTLSR-EDAEQVALEVDLNQKK---RRRKKQDGANELGVNNLLENATVQAGPSKGEKHKNKCQAIRPELKEGECSKEQMLSCTQNIDGIVGFASTEKVEKRTDPILSLSNQQDATSVATESSESSTSDLPSFEVGIRALCEVNNAEGSCIEERNVDLKNNSLEIDQTENVKPMLRGRFQRPKPNLSR-AGKKSVLSQGKTESESKNSHSKTSVEKNHVEKDKMNTLDILRMETTERENPEAETVSVLGEKNCLQEGSQLKALRP-VQVRGRLQKPKPNAGKAAERKEILISQEEIGANVEKNENESCADRDTPQHMEDQSRKDFEEEDVILQPEKNDSFQNVQPDEPKVLNECLSVQENNKANKLNQVPILRTRFQKPKPNIGRGTGRREISSKEEVLEKILVSGEMAAALRETVRLDTSPKEMVPAEINTKEMQSDLKETGRRAISPREKILDVIDDTIEMETGLKAMGR-EICLREKTPEVIDATEEIDKDLEEAGRREISPQKNGPEEVKPLGEVETDLKATGNESSPREKTPEVTDATEEIDKNLEETGRRKISPRENGPEEVKPVDEMETDLNATGRESSPREKTPEVIDATEEIDLEETEREVSPQENGLEEVKPLGEMETDLKATGRDSFPRGKTPEVIDAIEEIEIDLEETEREISPQENGLEEVKPLGEMQTDLKATGREISPREKTPEVIDATEEIDKDLEETGRRE-ISPEENGPEEVKPVDEMETDLKTTGREGSSREKTREVIDAAEVIETDLEETEREISPQENGPEEVKPVGKMETDLKEIREEISQREKVLAEFSAIREKEIDLKETGKRDIPIMEKVSGKMAVVEEMEADLKETGKEN--FRERGSEEICVTEEKVAELKQTGKTDISPRENELEETSTSRQTDTHLMQSGSNDFSAVPSLDIQNISSEVLSMMHTPVEEKRNSEKEVSSHFSHFKISSQTHESDKTEVQGIQSPDVPEQFSDINLSKSLPQEQKPLEIKPAPFVRSRFKRPKPNLARAALKRETTESEKYIYEKKSETKKMETIVMQENNEQTDTLPSQHDEASLMISREKDTLGHRNEE-AVILPCTQTERNLSPSNSCEPKEESQSAPVQKNDSVVSVGTNNVNTFQQEMKESVIQTARQVRGRLQRPRPNIRKTGQRQIVDKGEAKGIIKEGRTILPKDETEKKVLTVSNSQIETEIEVP-SSAVPEHRMYENQSQVVLVENLHVNKT---NETIRHENKPYVPSSAQMTRRKFQKAKPNLGRAHSKKEEPVLEKVTTDQSKEGKPEDHLLQKGASNTQLLLKEKAELLTSLEVSARKDCVGSKESALAKIDAELEEVGPSRRVGEETVGDNSPSSVVEEQYLNKLTSC--PQPLNETSYSKIALDGKTTISSTSEYERNRGERRSHKKFKPNVTRGRGSKRVRGKTSKKEPRASKAMLVTLRASQEED-DDADDFESDYEEESYHLAPEEVNKAPVFVPVGLRSPEPVSAQIEETMEELEITVNVPDVGCIAVVEHELPNTDVTTEEMKQEENLSVP-FEMTTSEHIQDEPGTNDGSTEAAITLLTMGDLVLQSEISSEQGDVGVCIIPHVHSKDKSHIPSSLDNVNHKIVHECQELSSPVITTSPASFEENKIVLEEQSSREEISLMEKVKENATPTRNTISKVTSNLRIRSRLAKPKPNLEKTLGTNRLDDYQEVSSLCVTKGAEMETQRETEKNASKATELENKNLGPVTTAENKDQSKLACVHGIKGTSISSEVNLTERNENQEESSQEVHMLSVAPVASSETGPCTLGLDRGLGENSVEEPQIKDSKGDSVLTLPVPEYTPTSIPEVQQENIINPQDLTVNLVANVPQDGEDEQAFILTLVEIPANAVEEFTDATAQFMPNPLLPAPILVKSVNTEERGDMSICLPATSVGQDAMGLSISGRDNSKKPPDNLDLVSRKRFQCRLDKNDHIPPAKKRSLTLRDDCQEYTTEVHSKELTNVFEETGESHKGQDIFLTSGSTLTTPEPQRQQVEAAFQSRGSRS-----PDACMDKNVPQLPQDEMIVSDKEERTDAAPKSQQMDSRTSSSKASLSRPGRRPLGFLSLICSKNSLESDEPMQVHSKKRLKPLIPGLRKKLKRSNPFNESQEKNRESSDLLPSPSVITTQSENIS---SSATQVSCDQPLLKEG-YKSAQKRAPQGEATTVSEYFFNDIFIEVDETE---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6YV30-1", "uniprot_id": "A0A8M6YV30_DANRE", "id": "A0A8M6YV30-1", "name": "", "aln": "MMRR---------------SRISVRPNVKP-----TGRAPTASREASAENAQAFQSPADSAPSEGSEVTAEKLN-TDPSIAAPEQTN----------EDASQSSSPSDQLEDTRRGEDASSKSSNALDSVSTSVTSGPQRRKRFTALPNLAKPRASQVSAKTPKSPIKSPVKPVTPIE----------------PEKS-----------TTNADIPAPVHNPRVPARRRPSGGSRP-AKSQLIPPESLQKDGESQKNGGLLEVVVPLTVQEGGVGTISPPDTVSDVNENRPTPPTVEEMVVQQESDS----------GAPPDQSQTDLLKEKLKKLKSTSKIIKSLTAVNDPADMIRLAQARKLR---------------------ELLKKEMVKDKEDKRK--LKMGLKERKAPKDHTKMTMRDLIYYLPVSNPMKSFT------EEEQKASETVLDDSPTPIS----------------------------SNTPDPPAVEEPVVEDADPEEDEERTEEAQEED---------KEPLLVPRVKVAEDGSLIIDEESLT-------------VQVLRANGPNPAEDRDPIFERG---------------------STTTYSSFRKGTYTKPWSNGETEMFFLAISMVGTDFSMIG-------QLFPHRGRLEIKNKFKKEEKNNAWRIDKAFKEKRRLDLDFFKKLMEQILNDEEE-------------KKNKSKEHFKLAKAKRKVRVAKRKGMDSSEDSDSDVVAG-----EKENEDLSNDGESDVTPKRRRGRAAKNTDRDIKRIYEEVDNPEDCENVTSDTQSPDDRLKDSESSKNINK--------------------------------------------------------------------------------------------------------------------------------------SPSIKPALLKGRPQKLIPNISRRWGERRP------KNNIQENRTSAKDEDPLKVP-------------------------------------------------------------------------------------------------------------------------------------SASKEEKDKKQ--ASVIIDLIDLDEEPDLS----------------------------------------------------------------------------AVQEQIFNKPTRSGRIPKLSQHVIQAAAEEEEDE-------------EEPSDPPTSSKVCVPSPGCRAKIKPGPRLKQGMQRRGKSR---------------------------LVTLLASGAEEDDDEER----------------------EEAEGCILSQEDFPSN--SEEENQAFVPMSLRPQDHFDSEVVETMEELDISANVPDILSASHNALCPES--------ACEQAVFPAGPVSYEHQLDLLVDVIEFLDPEHMEVCKEINNEAAQTLLTIGNSAQMIQTSEMPCLSGHDIDVHEEIANEEVFTETAIMSDPSISCYSEMR--------------------------------------------SDVELSNSETQIPEPPTSIEEPIKSQNSMSHPGPVQQVSQDLAS-----------TFVPS---STRGRFAKPKPNIG---------------------------------------LKSRRAPQQQISSELPADSVENSKSLTSAEQDEKQ-----KASMQEIADELSDSSNIHP----------------EVQQPGTVSDRREDAPERLTGGDSGSAVSLKRKDEDEIT--------EEKIKEHEEAKSDPVLINSESE---------------SQSTLDEAPKPVRRN--------RGPKPK------------------------------PNLTQASRKKHTQTQLNTPSLTTGITFTKSPEEGAVITTEPDVSQRATQQEVTLRLESTQAVKDISPVVSEDNSRPN-----------TLVRLDEEQNITAPDEAFEDSSVKHSRCESKDASEES---------MFILSLTEIPPALQQGACLRTEPLPPTIEPGLHSHGQSVNESKEVSHLLLTDALVLVSEEEEKEGEEEDKSRRGQLKRKTPASTSQESTKSESQAEDCVVEVSESPVAEETDEHLEK----------------------------------KRKPPERTRRAKLQVKPIP-------------------------VMRKNTRGVKEDTAALTLKETPSLPISTAETKPEQTDPTVISTS----------------------------------------------------------ASSDNIPSSEES----------------------VQEESSQGTVG--------------------------------------------------QVDITVKETDELASGSDSQTATQITPVATSGPLTRPGRKPKGFLSFISTKSTQG-----APTRHRGSKPGVNTARPDRKQ----VASASANLGVKRALPTPASTTEQR--------------------------------SEEEPTSVSKYFFSDIFTEVDELEDMD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VJZ3-1", "uniprot_id": "Q9VJZ3_DROME", "id": "Q9VJZ3-1", "name": "", "aln": "---------------------MSMRR---------QRIKAPANLSLIKRKPRREELPTAKKEDEEEEAVVVEAEAESPPVAS---------------TPAAELELEADAIAFKMPASSAGQLEEVFHSDLEDNVIQMDLQKTTNGFPMSPSKAQARQRVRPTPVFGQRR------------------------------------------NSFVGSPMASDYEGDYQSPATPTRR---ERYLSGSSSGTPLQQQVHSPMPPSPYKYLP--------PASPGMGRIRTESTCSTYSEGGSKQRKGDD------------------------------RSQSQIGQRLNARRDFETR------------------------------------------------------FNKGVPDKSTFKMMDMIFYNPENNP-----------MVPKQSVTTIKDES---------------------------------------------GGDDSKPAVSQLLEPKGESTS-----------AMLVPQLKLDANGEMIIDEKTLE-------------IETTAEVEARKVLANSSLILMD--------------------ETTGDNGFYKRHKRTPYWTSDETVRFYRSLQIIGTDFSLMC-------QMFPTRSRRDLKLKYKKEERTNGQLINKALLYPKAFNIQELKDQLEEEDR-------------------------------------------------------------EREENDRKWREIARALPGNPKKRSRVQQQSKASRALNDGDVVYENEHVTSTKLGKHAWAKR----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RKELETDENDG----------------------------------------------------------------------------------------------------------------------------------------------SAPAKRKPKAK-------------------------------------------------------------------------------------------------------RRSPKVSVPAATESLSDVAAIK--------------------------QEKTIKTEQTSSHLPTG---------------------------------------------------------------------------------------------------GELQAELNGLLMDDPVEYDVDVNKPRD--------KTIINMDDGTLSYVS------------DVEPAPETPNRKAETYLINFIE--DQDHELITPDDPIPPSTTEPDIEQILAELAEGSLALVSSLDPEHEDRVLNEIYMLDKKTG-----------------------------------------------------------ELCETPLKIPEHIVQCIMNVMQPED---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P46678-1", "uniprot_id": "TFC5_YEAST", "id": "P46678-1", "name": "Transcription factor TFIIIB component B''", "aln": "------------------MSSIVNKSGTRFAPKVRQRRAATGGTPTPKPRTPQLFIPESKEIEEDNSDNDKGVDENETAIVE-----------------KPSLVGERSLEGFTLTGTNGHDNEIGDEGPIDASTQNPKADVIEDNVTLKPAPLQTHRDQKVPRSSRLASLSK---------------------------------------DNESRPSFKPSFLDSSSNSNGTARRLSTISNKLPKKIRLGSITENDMNLKTFKRHRVLGKPSSAKKPAGAHRISIVSKISPPTAMTDSLDRNEFSS-----------------ETSTSREADENENYVISKVKDIPKKVRDGESAKYFIDEE--------------------------------------------NFTMAELCKPNFPIGQISENFEKSKMAKKAKLEKRRHLRELRMRARQEFKPLHSLTKE------------------------------------EQEEEEEKRKEERDKLLNADIPESD---------RKAHTAIQLKLNPDGTMAIDEETMVVDR---------HKNASIENEYKEKVDENPFANLY------------------------NYGSYGRGSYTDPWTVEEMIKFYKALSMWGTDFNLIS-------QLYPYRSRKQVKAKFVNEEKKRPILIELALRSKLPPNFDEYCCEIKKNIG------------------------------------------------------------------TVADFNEKLIELQNEHKHHMKEIEEAKNTAKEEDQTAQRLNDANLNKKGS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGIMTN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DLKVYRKTEVVLGTIDDLKRKKLKERN-----------------------NDDNEDNEGSEEEPEIDQ-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . .. * . .. . . . .. . . ... . :* . : . : : . .. . : . : . . . . : : : *: . . : . . : . . : . . * : :: . :: : . : .: :. . . : : . : . : . . ", "identical_positions": 4, "similar_positions": 74, "identity": "0.15%" }, { "cls_id": "homologset.agr.RGD:1308513", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U2M6-1", "uniprot_id": "DCAF8_RAT", "id": "Q5U2M6-1", "name": "DDB1- and CUL4-associated factor 8", "aln": "--------------------------------------------------------MSSKRP-STDGRRDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTSTE---SRGTDTESSGEEKDSDS------------------------------MEDTGHYSINDENRVHGHSD-EEEEEE------QPRHRVQRKRASRDQDSSDDERALEDWVSSETT------------------------------ALPRPRWQALPALRERE------------LGSSARFVYEACGARVFVQRFRLQHGLEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFESGHKSNVFQAKFLPNSGDSTLAMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCTFLSAGEDAVVFTIDLRQDRPASKLVVTKEKEK----KVGLYTIYVNPANTHQFAVGGRDQFVRIYDQRKIDENENNGVLKKFCPHHLVNSESKANITCLVYSHDGTELLASYNDEDIYLFNSSHSDGAQYIKRYKGHRNNATVKGVNFYGPKSEFVVSGSDCGHIFLWEKSSCQIIQFMEGDKGGVVNCLEPHPHLPVLATSGLDHDVKIWAP-TAEASTELTGLKDVIKKNKRE-----RDEDSLHHTDLFDSHMLWFLMHHLRQR---------RHHRRWREPGVGATDADSDESPSSSDTSDEEEGPDRVQCMPS------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N7N5-1", "uniprot_id": "DCAF8_MOUSE", "id": "Q8N7N5-1", "name": "DDB1- and CUL4-associated factor 8", "aln": "--------------------------------------------------------MSNKRPNTTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTSTE---SRGTDTESSGEEKDSDS------------------------------MEDTGHYSINDESRGHGHSD-EEDEE-------QPRHRGQRKRASRDQDSSDDERALEDWVSSETT------------------------------ALPRPRWQALPALRERE------------LGSSARFVYEACGARVFVQRFRLQHGLEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFESGHKSNVFQAKFLPNSGDSTLAMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCTFLSAGEDAVVFTIDLRQDRPASKLVVTKEKEK----KVGLYTIYVNPANTHQFAVGGRDQYVRIYDQRKIDENENNGVLKKFCPHHLVNSESKANITCLVYSHDGTELLASYNDEDIYLFNSSHSDGAQYIKRYKGHRNNATVKGVNFYGPKSEFVVSGSDCGHIFLWEKSSCQIIQFMEGDKGGVVNCLEPHPHLPVLATSGLDHDVKIWAP-TAEASTELTGLKEVIKKNKRE-----RDEDSLHHTDLFDSHMLWFLMHHLRQR---------RHHRRWREPGVGATDADSDESPSSSDTSDEEEGPDRVQCMPS------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5TAQ9-1", "uniprot_id": "DCAF8_HUMAN", "id": "Q5TAQ9-1", "name": "DDB1- and CUL4-associated factor 8", "aln": "--------------------------------------------------------MSSKGS-STDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTSTE---SRGTDTESSGEDKDSDS------------------------------MEDTGHYSINDENRVHDRSE-EEEEEEEEEEEEQPRRRVQRKRANRDQDSSDDERALEDWVSSETS------------------------------ALPRPRWQALPALRERE------------LGSSARFVYEACGARVFVQRFRLQHGLEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFESGHKSNVFQAKFLPNSGDSTLAMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCTFLSAGEDAVVFTIDLRQDRPASKLVVTKEKEK----KVGLYTIYVNPANTHQFAVGGRDQFVRIYDQRKIDENENNGVLKKFCPHHLVNSESKANITCLVYSHDGTELLASYNDEDIYLFNSSHSDGAQYVKRYKGHRNNATVKGVNFYGPKSEFVVSGSDCGHIFLWEKSSCQIIQFMEGDKGGVVNCLEPHPHLPVLATSGLDHDVKIWAP-TAEASTELTGLKDVIKKNKRE-----RDEDSLHQTDLFDSHMLWFLMHHLRQR---------RHHRRWREPGVGATDADSDESPSSSDTSDEEEGPDRVQCMPS------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W091-1", "uniprot_id": "Q9W091_DROME", "id": "Q9W091-1", "name": "DDB1- and CUL4-associated factor 8", "aln": "MDVEDSVASGAASACKRQKRNTDSQNDGEPEDAAQIGEENTVAESQPLINFDTIVTHNNNGESDMEGKENQLQDESEQSEEHLANKVGPEELPEIEQAGSSNLAHQLSPEAASTVLASDEPDASTGVIEPSDSEDYPPTSPTPIEASEAVSSPRFNPRNIPPTRSYRRISIELVGSYSDTSDSEEHELEEGTEHAEEYSDDAPEPHIAESADDSSSNDDMGPYSLSSEDETTTEVENLQDEVEFNEDINPADREKVDYAVNQVMCKCKPKYTWNYDQELLQREHNIINRIDWRGGHTSASSFGQGYYGSRQVVEQMTLLSSLNVHHGCVNSLNFNRAGDLICSGSDDLTIVVWDWAKEKQLHRFRSGHNMNIFQTKFIDSAGCLDIVSSSRDGQVRRSVIPPSGGVIKPIRLYTHSESVHKIIVVPHSRHELMSAGEDAAVKHFDLRASNAATTMMRCVYNDENERGRVRLFSIAHHPY-APEFCVSGSDDILRVYDKRNLAK-----AIHQMAPRNLLEAQ-ITQITCAVYNHSGSEILASYSDAGIYLFDSRNYNRGDYLHCYKGHINSRTIKGVNFFGPRSEYIVSGSDCGNIFFWDKNTEAIINYMKGDHVGVVNCLEPHPWMPVLATSGLEHDVKIWTPQGPERKLPEDLLKQTLQRNFRCNIVESIDLDINNFQYFIRGFLQGSGASHLRQRHTSSLGHQMRDNSSSRSNGSNASNPTSHRRNSNSSDDTNDEGADADAALDTLHCRTQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 202, "similar_positions": 214, "identity": "26.75%" }, { "cls_id": "homologset.agr.RGD:1308514", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZGX9-1", "uniprot_id": "D3ZGX9_RAT", "id": "D3ZGX9-1", "name": "", "aln": "---MLVTGFILWASLLTGAWPAAPIQDQ--------LPATPRVRLSFKELKATGTAHFFNFLLNTTDYRILFKDEDHDRMYVGSKDYVLSLDLHDINR---EPLIIHWAASPQRIEECILSGKDGNGECGNFVRLIQPWNR-THLYVCGTGAYNPMCTYVNRGRRSQAPPWTQMQVVRGRGSRATDGADRPTPTAPRQDYIFYLEPEKLESGKGKCPYDPKLDTASALIN-------EELYAGVYIDFMGTDAAIFRTLGKQTAMR--------TDQYNSRWLNDPSFIHAELIPDSAERNDDKLYFFFRERSAEAPQN-PAVYARIGRICLNDDGGHCCLVNKWSTFLKARLVCSVPGEDGIETHFDELQDVFVQQTQDVRNPVIYAVFTSSGSVFRGSAVCVYSMADIRMVFNGPFAHKEGPNYQWMPFSG-KMPYPRPGTCPGGTFTPSMKSTKDYPDEVINFMRTHPLMYQAVYPLQRRPLVVRTGAPYRLTTVAVDQVDAADGRYEVLFLGTDRGTVQKVIVLPKDDQEVEELMLEEVEVFKEPAPVKTMTISSKRQQLYVASAVGVTHLSLHRCQAYGAACADCCLARDPYCAWDGQACSRYTASSK----RRSRRQDVRHGNPIRQCRGFNSNANKNAIESVQYGVAGSAAFLECQPRSPQATVKWLFQRDPSDRRREIRAEDRFLR-TEQGLLLRALQLGDRGLYSCTATENNFKHVVTRVQLHVLGRDAVHAALFPP--LAVSVPPPPGTGPPTPPYQELAQLLAQPEVGLIHQYCQGYWRHVPPNPREAPGALRPPELQDQKKPRNRRHHPPDT--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88632-1", "uniprot_id": "SEM3F_MOUSE", "id": "O88632-1", "name": "Semaphorin-3F", "aln": "---MLVTAFILWASLLTGAWPATPIQDQ--------LPATPRVRLSFKELKATGTAHFFNFLLNTTDYRILLKDEDHDRMYVGSKDYVLSLDLHDINR---EPLIIHWAASPQRIEECILSGKDGNGECGNFVRLIQPWNR-THLYVCGTGAYNPMCTYVNRGRRAQALPWTQMQVVRGRGSRATDGADRPTPTAPRQDYIFYLEPEKLESGKGKCPYDPKLDTASALIN-------EELYAGVYIDFMGTDAAIFRTLGKQTAMR--------TDQYNSRWLNDPSFIHAELIPDSAERNDDKLYFFFRERSAEAPQN-PAVYARIGRICLNDDGGHCCLVNKWSTFLKARLVCSVPGEDGIETHFDELQDVFVQQTQDVRNPVIYAVFTSSGSVFRGSAVCVYSMADIRMVFNGPFAHKEGPNYQWMPFSG-KMPYPRPGTCPGGTFTPSMKSTKDYPDEVINFMRTHPLMYQAVYPLQRRPLVVRTGAPYRLTTVAVDQVDAADGRYEVLFLGTDRGTVQKVIVLPKDDQEVEELMLEEVEVFKEPAPVKTMTISSKRQQLYVASAVGVTHLSLHRCQAYGAACADCCLARDPYCAWDGQACSRYTASSK----RRSRRQDVRHGNPIRQCRGFNSNANKNAVESVQYGVAGSAAFLECQPRSPQATVKWLFQRDPSDRRREIRAEDRFLR-TEQGLLLRALQLGDRGLYSCTATENNFKHIVTRVQLHVLGRDAVHAALFPP--LAVSVPPPPGTGPPTPPYQELAQLLAQPEVGLIHQYCQGYWRHVPPRPREAPGALRPPELQDQKKPRNRRHHPPDT--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13275-1", "uniprot_id": "SEM3F_HUMAN", "id": "Q13275-1", "name": "Semaphorin-3F", "aln": "---MLVAGLLLWASLLTGAWPSFPTQDH--------LPATPRVRLSFKELKATGTAHFFNFLLNTTDYRILLKDEDHDRMYVGSKDYVLSLDLHDINR---EPLIIHWAASPQRIEECVLSGKDVNGECGNFVRLIQPWNR-THLYVCGTGAYNPMCTYVNRGRRAQATPWTQTQAVRGRGSRATDGALRPMPTAPRQDYIFYLEPERLESGKGKCPYDPKLDTASALIN-------EELYAGVYIDFMGTDAAIFRTLGKQTAMR--------TDQYNSRWLNDPSFIHAELIPDSAERNDDKLYFFFRERSAEAPQS-PAVYARIGRICLNDDGGHCCLVNKWSTFLKARLVCSVPGEDGIETHFDELQDVFVQQTQDVRNPVIYAVFTSSGSVFRGSAVCVYSMADIRMVFNGPFAHKEGPNYQWMPFSG-KMPYPRPGTCPGGTFTPSMKSTKDYPDEVINFMRSHPLMYQAVYPLQRRPLVVRTGAPYRLTTIAVDQVDAADGRYEVLFLGTDRGTVQKVIVLPKDDQELEELMLEEVEVFKDPAPVKTMTISSKRQQLYVASAVGVTHLSLHRCQAYGAACADCCLARDPYCAWDGQACSRYTASSK----RRSRRQDVRHGNPIRQCRGFNSNANKNAVESVQYGVAGSAAFLECQPRSPQATVKWLFQRDPGDRRREIRAEDRFLR-TEQGLLLRALQLSDRGLYSCTATENNFKHVVTRVQLHVLGRDAVHAALFPP--LSMSAPPPPGAGPPTPPYQELAQLLAQPEVGLIHQYCQGYWRHVPPSPREAPGAPRSPEPQDQKKPRNRRHHPPDT--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32U4S8-1", "uniprot_id": "A0AB32U4S8_DANRE", "id": "A0AB32U4S8-1", "name": "", "aln": "---MLLDSLWPVQVLLVLSVLTLVLGNE--------PQNAPRVFLSFKDLRSTGTAHYFSFLLNTSDYRILRMDEDHDRMYVGSKDYILSLDLHDINR---EPLIIHWPVSPQRKTECVLSGKDTNGECGNFIRLIEPWNR-THLYICGTGAYNPVCTYVNRGRKPMTAMHLQMPQTRGRASRAAEPETVFDETG-LQEYVFHLEPGKEDSGKGKCPYDPKLNSVSALIN-------GELYAGVYIDFMGTDSAIFRTLGKNAVMR--------TDQYNSRWLNDPSFVHVHLIPDSGEKNDDKLYFFFREKSSEMGQS-PKSQSRIGRICLNDDGGHCCLVNKWSTFLKARLICSVPGADGIETHFDELRDVYIQPTQDTKNPVIYGVFSVSGSVFKGSAVCVYSMADIRMVFNGPFAHKEGPNYQWVAYTG-KIPYPRPGTCPGGTFTPNMKSTKDYPDEVINFMRNHPTMYNSVYPVHKRPLVVRTNVDYEFTTITVDQVTAADGNYEVLFLGTDKGTVQKVIVLPSDDLQTEELVLEEVEVFKVPTSITTMKISSKRQQLYVASAVGVTHMALHRCDVYGEACADCCLARDPYCAWDGKSCSRYSASQKRLPFRRSRRQDVKYGNPIRQCRGYNSNINKNTLETVQYGVEGSSTFLECQARSPHAAIKWHLHRDNSDRRREVRSDGRVLK-TDQGLLLRSLQSSDSGIYICTATEKNFKHTLVKLQLLVLTNQAVNNILVDTGRPVVSPLQSSAWTPSAGQYKDLLTILSQPEMGLINQYCQDYWQYGDPLTG-VIKAKDLKELKEQKKPRNRRHHGDEEET", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24323-1", "uniprot_id": "SEM2A_DROME", "id": "Q24323-1", "name": "Semaphorin-2A", "aln": "MSLLQLSPLLALLLLLCSSVSETAADYENTWNFYYERPCCTGNDQGNNNYGKHGADHVREFNCGKLYYRTFHMNEDRDTLYVGAMDRVFRVNLQNISSSNCNRDVINLEPTRDDVVSCVSKGKSQIFDCKNHVRVIQSMDQGDRLYVCGTNAHNPKDYVIYAN----------------------------LTHLPRSEYVIGVG-----LGIAKCPYDPLDNSTAIYVENGNPGGLPGLYSGTNAEFTKADTVIFRTDLYNTSAKRLEYKFKRTLKYDSKWLDKPNFVGSFDIG-------EYVYFFFRETAVEYINCGKAVYSRIARVCKKDVGGKNLLAHNWATYLKARLNCSISG--EFPFYFNEIQSVYQLPSDKSR---FFATFTTSTNGLIGSAVCSFHINEIQAAFNGKFKEQSSSNSAWLPVLNSRVPEPRPGTCVN--------DTSNLPDTVLNFIRSHPLMDKAVNHEHNNPVYYKRDLVFTKLVVDKIRIDILNQEYIVYYVGTNLGRIYKIVQYYRNG-ESLSKLLDIFEVAPN-EAIQVMEISQTRKSLYIGTDHRIKQIDLAMCNRRYDNCFRC--VRDPYCGWDKEANT-----------CRPYELDLLQDVANETSDICDSSVLKKKIVVTYGQSVHLGCFVKIPEVLKNEQVTWYHHSKDKGRYEIRYSPTKYIETTERGLVVVSVNEADGGRYDCHLGG----------SLLCSYNITVDAHRCTP---------PNKSNDYQKIYSDWCHEFEK------------YKTAMKSWEKKQAQCSTRQNFSSNQHPNEIFRKPNV---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : ** : . . . :: *: * .* .. ** : :**:* :***: * :: ::*::*. : :*: : : .*: .**. :* *.:*:*:. :: :**:***.*:** : . .:*:: : * .****** ::.: :: **:*. :* :*:.**** :: : * :*:*:**:.*.*: * : :****** : * : :**.*:* :* **: *.::*:*:***** **:.* : :*:*::.*: ::. : ::..*: * . : ***** : : :*: .*** * .:...* *:. . ::* ****** . .*.: ** *:**:*.** * ::* :..*: : . : .: :: : .* * ::**: * : *:: :. : . :*: .** .: .* **..*:.**:.: :.:: * *: * * .*****.** :: : *. . *: . . . . :*. *: : . . *:: : :.* : . .* . : : :. *::**:: ::: .* * * * .* . :*. . . *.: : : * . . : ..:::*.: :: ", "identical_positions": 163, "similar_positions": 236, "identity": "19.73%" }, { "cls_id": "homologset.agr.RGD:1308515", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4A4S5-1", "uniprot_id": "D4A4S5_RAT", "id": "D4A4S5-1", "name": "", "aln": "--MAWKQTP-LLLLVYMITTCSA-----RDRTDLLNVCMDAKHHKTKPGPEDKLHDQCSPWKRNACCSVNTSQELHKDNSRLYNFNWDHCGEMTPACKRHFIQDACLYECSPNLGPWIQQAGQSWRKERFLDVPLCKEDCQEWWEACRTSFTCKRDWHKGWDWTSGINKCPDTAPCRTFQYYFPTPASLCEGLWSHSYKVSNYSRGSGQCIQMWFDSTQGNPNEEVVKFYASFMTS--GTVYHAAILLVPSLAPVLSLWLPD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q05685-1", "uniprot_id": "FOLR2_MOUSE", "id": "Q05685-1", "name": "Folate receptor beta", "aln": "--MAWKQTP-LLLLVYMVTTGSG-----RDRTDLLNVCMDAKHHKTKPGPEDKLHDQCSPWKKNACCSVNTSQELHKADSRLY-FNWDHCGKMEPACKSHFIQDSCLYECSPNLGPWIQQVDQSWRKERFLDVPLCKEDCHQWWEACRTSFTCKRDWHKGWDWSSGINKCPNTAPCHTFEYYFPTPASLCEGLWSHSYKVSNYSRGSGRCIQMWFDSTQGNPNEDVVKFYASFMTS--GTVPHAAVLLVPSLAPVLSLWLPG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P14207-1", "uniprot_id": "FOLR2_HUMAN", "id": "P14207-1", "name": "Folate receptor beta", "aln": "--MVWKWMPLLLLLVCVATMCSA-----QDRTDLLNVCMDAKHHKTKPGPEDKLHDQCSPWKKNACCTASTSQELHKDTSRLYNFNWDHCGKMEPACKRHFIQDTCLYECSPNLGPWIQQVNQSWRKERFLDVPLCKEDCQRWWEDCHTSHTCKSNWHRGWDWTSGVNKCPAGALCRTFESYFPTPAALCEGLWSHSYKVSNYSRGSGRCIQMWFDSAQGNPNEEVARFYAAAMHVNAGEMLHGTGGLLLSLALMLQLWLLG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P41439-1", "uniprot_id": "FOLR3_HUMAN", "id": "P41439-1", "name": "Folate receptor gamma", "aln": "MDMAWQMMQ-LLLLALVTAAGSAQPRSARARTDLLNVCMNAKHHKTQPSPEDELYGQCSPWKKNACCTASTSQELHKDTSRLYNFNWDHCGKMEPTCKRHFIQDSCLYECSPNLGPWIRQVNQSWRKERILNVPLCKEDCERWWEDCRTSYTCKSNWHKGWNWTSGINECPAGALCSTFESYFPTPAALCEGLWSHSFKVSNYSRGSGRCIQMWFDSAQGNPNEEVAKFYAAAMNA-------G----APSRGIIDS-----", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.*: ****. : : *. : *********:******:*.***:*:.******:****:..******* **** *******:* *:** *****:*************:*..*******:*:********..*** *:**.*** :**:**:*:**:*:** * * **: ******:*********:**********:********:******:*.:***: * . * . : . ", "identical_positions": 162, "similar_positions": 48, "identity": "61.83%" }, { "cls_id": "homologset.agr.RGD:1308516", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q3UA06-1", "uniprot_id": "PCH2_MOUSE", "id": "Q3UA06-1", "name": "Pachytene checkpoint protein 2 homolog", "aln": "------------------------------------MDEAVGDLKQALPCVAESPAVHVEVLQRS-------------------------GSTAKKEDIKSSVYRLLNRHNIVFG--DYVWTEFDDPFLSRNVQSVSIVDTELKAKDPQPIDLSACTIALHIFQLNEEGPSSE----------------------------------------------------------------NLDEETENIIAASHWVLPAAEFHGLWDSLVYDVEVKSHLLDYVMTTVLFS--DKNVDSN------LITWNRVVLLHGPPGTGKTSLCKALAQKLTIR--------LSSRYRYGQLIEINSHSLFSKWFSESGKLVTKMFQKIQDLIDDKE---ALVFVLIDEVESLTAARNACRAGAEPSDAIRVVNAVLTQIDQIKRHSNVVILTTSNITEKIDVAFVDRADIKQYIGPPSAAAIFKIYLSCLEELMKCQIIYPRQQLLTLRELEMIGFIENNVSKLSLLLSEISRKSEGLSGRVLRKLPFLAHALYIQAPSVTIEGFLQALSLAVDKQFEEKKKLSAYV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5XHZ9-1", "uniprot_id": "PCH2_RAT", "id": "Q5XHZ9-1", "name": "Pachytene checkpoint protein 2 homolog", "aln": "------------------------------------MDDAVGDLKQALPCVAESPAVHVEVLQRS-------------------------GSTAKKEDIKQSVYRLLKRHNIVFG--DYVWTEFDEPFLTRNVQSVSIVDTELKAKDPQPIDLSACTIALHIFQLNEEGPSSE----------------------------------------------------------------NLDEETENIIAASHWVLPAAEFHGLWDSLVYDVEVKSHLLDYVMTTLLFS--DKNVDSN------LITWNRVVLLHGPPGTGKTSLCKALAQKLTIR--------LSSRYRYGQLIEINSHSLFSKWFSESGKLVTKMFQKIQDLIDDKE---ALVFVLIDEVESLTAARNACRAGAEPSDAIRVVNAVLTQIDQIKRHSNVVILTTSNITEKIDVAFVDRADIKQYIGPPSAAAIFKIYLSCLEELMKCQIIYPRQQLLTLRELEMIGFIENNVSKLSLLLSEISRKSEGLSGRVLRKLPFLAHALYIQAPSVTIEGFLQALSLAVDKQFEEKKKLSAHV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q15645-1", "uniprot_id": "PCH2_HUMAN", "id": "Q15645-1", "name": "Pachytene checkpoint protein 2 homolog", "aln": "------------------------------------MDEAVGDLKQALPCVAESPTVHVEVHQRG-------------------------SSTAKKEDINLSVRKLLNRHNIVFG--DYTWTEFDEPFLTRNVQSVSIIDTELKVKDSQPIDLSACTVALHIFQLNEDGPSSE----------------------------------------------------------------NLEEETENIIAANHWVLPAAEFHGLWDSLVYDVEVKSHLLDYVMTTLLFS--DKNVNSN------LITWNRVVLLHGPPGTGKTSLCKALAQKLTIR--------LSSRYRYGQLIEINSHSLFSKWFSESGKLVTKMFQKIQDLIDDKD---ALVFVLIDEVESLTAARNACRAGTEPSDAIRVVNAVLTQIDQIKRHSNVVILTTSNITEKIDVAFVDRADIKQYIGPPSAAAIFKIYLSCLEELMKCQIIYPRQQLLTLRELEMIGFIENNVSKLSLLLNDISRKSEGLSGRVLRKLPFLAHALYVQAPTVTIEGFLQALSLAVDKQFEERKKLAAYI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PH52-1", "uniprot_id": "PCH2_DANRE", "id": "Q6PH52-1", "name": "Pachytene checkpoint protein 2 homolog", "aln": "------------------------------------MDISDHHMTDVG---IIRPDVHIEVHVKS-------------------------QSTAKRSDVRTHVLSLLDRHSTVLR--SFKWMDFDNEFLTKNVESVTIAD----VTGPKLVDLKVHNLCIHIFTLNDDSPSTL----------------------------------------------------------------NLEEEEE-LSAANLWLLPAVEFHGVWESLIYEEGIKTQLLDYVSTTIFFS--DKNVDSN------LIAWNRVVLLHGPPGTGKTSLCKGLAQKLSIR--------LSDRYAHSQFVEINSHSLFSKWFSESGKLVTKMFQKIQELIDDKD---ALVFVLIDEVESLTAARSAAQAGTEPSDAIRVVNSVLTQLDQIKRHPNVVILTTSNVTEKIDLAFVDRADIKQYIGPPSAKAIFNIYLSSLEELMKRQIIYPRQQLVSLEELETMNFMESDVTRLSLCLMNISQRSVGLSGRALRKIPFLAHALYGKTSTMTLKGFLTAMEHAVNKQRQEQASLVNCV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P38126-1", "uniprot_id": "PCH2_YEAST", "id": "P38126-1", "name": "Pachytene checkpoint protein 2", "aln": "MSYIVDLQVRGSSLRVIKCMFREDEQISSLHSGSDSKQNSNKKLGEFLNLLKAVVKRKLESFPKDRLKTSIITGQELMREGQGSIEIKDPPTEAQQHLIRSLAKVLLHQFSSINGKVNTVNEGQDNLFLSLFVKKISIEQQSTSHVSIKLNFHEKINLGQHIDSILDSEETNESDTYHMGSVDEFIIYPFCCLEEQDELKNGSILSTEFDKIDLELDEDDGFEGETLNNCINSVGNFDIPLSKQTLNLVNISYLPGTTFEGQWESLYFGNNIKERLYSYATISLKIARFKQTGDSNQEDITTLITNNKLLLVHGPPGTGKTTLCKALCQKLSVRREFSDGSDTIDTNYKGIIIELSCARIFSKWFGESSKNISIVFKDIEELLKVNEGRGIFICLLIDEVEAIASSRTNLSSRNESTDGIRVVNTLLTQLDRLKKYHNFLALATSNLLDSLDDAFVDRADGVFYVGNPTAEGILHILKVCIEEMITSGIILFHARSTGVKFFNKYQDILR--------KIAIKCSTVDISGRTIRKLPLMCLSEYFRTFPVDDDEFVLALAMSARKLSAARK------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : .: : ::* :. : *:: :. . **.:.. : . *: **: *:.::* : . : . .: ** : :. :. :: . : : .. **.. *.* *:** : :* :* .*. :: :: .:. :** **: *:::*:*********:***.*.***::* . . ::*:.. :*****.**.* :: :*:.*::*:. :: :: :******:::::*. : *.:*.*****::***:*::*:: *.: *:***: :.:* ******* *:* *:* .*::* .:**::. ** : : :. :: : *. : .:***.:**:*::. : * :: .: . *: *: :. * : ", "identical_positions": 109, "similar_positions": 158, "identity": "18.86%" }, { "cls_id": "homologset.agr.RGD:1308517", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5HZK1-1", "uniprot_id": "CEP44_MOUSE", "id": "Q5HZK1-1", "name": "Centrosomal protein of 44 kDa", "aln": "MATGDLKRSLRKLEQVLRSLNYPNEVDYVGLIKGDTAASLPIISYSLTSYSPYVAELLMESSIELIAKNDVRFTDTVYKLLRDQFDYKPILTKKQFIQSGFAEWKIEIVCDILNCVMKKHKELIGLDKNSSCQRKKNVSEKPEPCSNSEKRPAEAVGIDITGRFMTSGKKKAVVIRHLYTDEKVGVPEGTVT-LADISQGCSESAEQSSDIRIPEAQDPEVKAELQDICDHPEITALQIALAECQEKLKQLTWIEKRLERLEAATHGKVMVDEKAWNNLLSRVTLLETEMLLSKKS-ESVERNVASQDCESISDVDFVPYDKNYSVGGAAGNYRSSGCSAVSSETAPGSSIVNYCVLREFSEETTIQKMERMKKMFEETAELLKCSSR--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3B7T8-1", "uniprot_id": "CEP44_RAT", "id": "Q3B7T8-1", "name": "Centrosomal protein of 44 kDa", "aln": "MATGDLKRSLRKLEQVLRSLNYPNEVDYVGLMKGDTAASLPIISYSLTSYSPHVAELLMESNIELIAKNDVRFTDTVYKLLRDQFDYKPILTKKQFIQSGFAEWKIEIVCDILNCVMKKHKKLIGLDKNSSCQRKKSISEKPEPCSSREKCPAEAVGIDVTGRFMTSGKKKAVVIRHLYTEENVGVPEGTVT-STEVSEGCDELEEQSSDIRIPEAQAPEVKAELQDMCDNPELTALQIALAECQEKLKKLTWIEKRLECLEATTKGKVMVDEKAWNNILSRVTLLETEMLLSKKN-ESVEPNTTSEDSESVSGVDVVPYDKKYSVEGPASTCHSSGYSTVSSATVPRSSTINYCGLNNFSEETTMQKMERMKKMFEETAELLKCSSR--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9C0F1-1", "uniprot_id": "CEP44_HUMAN", "id": "Q9C0F1-1", "name": "Centrosomal protein of 44 kDa", "aln": "MATGDLKRSLRNLEQVLRLLNYPEEVDCVGLIKGDPAASLPIISYSFTSYSPYVTELIMESNVELIAKNDLRFIDAVYKLLRDQFNYKPILTKKQFIQCGFAEWKIQIVCDILNCVMKKHKELSSLQKIPSQQRKKISSGKSEPPLGNEKISAEAVGVDISGRFMTSGKKKAVVIRHLYNEDNVDISEDTLSPITDVNEAVDVSDLNATEIKMPEVKVPEIKAEQQDVNVNPEITALQTMLAECQENLKKLTSIEKRLDCLEQKMKGKVMVDENTWTNLLSRVTLLETEMLLSKKNDEFIEFNEVSEDYASCSDMDLLNPHRKSEVERPASIPLSSGYSTASSDSTPRASTVNYCGLNEISEETTIQKMERMKKMFEETAELLKCPNHYL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***********:****** ****:*** ***:***.**********:*****:*:**:***.:*******:** *:*********:************.*******:**************:* .*:* .* **** * *.** . ** .*****:*::******************.:::*.:.*.*:: :::.:. . ::::*::**.: **:*** **: :**:**** ******:**:** *****: ** :*******::*.*:****************. * :* * .*:* * *.:*.: .:: .* .*. *** *:.** :.* :* :*** *.::*****:*******************..: ", "identical_positions": 248, "similar_positions": 89, "identity": "63.59%" }, { "cls_id": "homologset.agr.RGD:1308518", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XI55-1", "uniprot_id": "NGLY1_RAT", "id": "Q5XI55-1", "name": "Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase", "aln": "----MASATLGSSSSSASPAVAELCQNTPETFLEASKLLLTYADNILRNPSDEKYRSIRIGNTAFSTRLLPVRGAVECLFEMGFEEG--ETHLIFPKKASVEQLQKIRDLIAVERRSRLDGS--SQKVEFSQHPAA-VRLPAEQPEDPTGLMQHSGNQPGQPLSLPSAPLVVGDSTIFKVLQSNIQHVQLYENPVLQEKALACIPVNELKRKSQEKLFRARKLDKGTKVSDE-----DFLLLELLHWFKEEFFHWVNNVVCSRCGR---ETRSRDEALPPNDDELKWGAKNVEDHYCDACQLSNRFPRYNNPEKLLETRCGRCGEWANCFTLCCRALGFEARYVWDYTDHVWTEVYSPSQQRWLHCDACEDVCDKPLLYEIGWGKKLSYIIAFSKDEVVDVTWRYSCKHEEVMSRRTKVKEELLRETINGLNKQRQLLLSESRRKELLQRIIVELVEFISPKTPRPGELGGRVSGSLAWRVARGETCLE-----RKEILFIPSENEKISKQFHLRYDIVRDRYIRVSDNN------ANISGWENGVWKMESIFRKVEKDWNMVYLARKEGSSFAYISWKFECGSAGLKVDNVSIRTSSQSFETGSVRWKLRSEMAQVNLLGDRNLRSYDDFCGATEVTLEAELSRGDGDVAWQHTQLFRQSLNDHAENGLEIIITFSDL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JI78-1", "uniprot_id": "NGLY1_MOUSE", "id": "Q9JI78-1", "name": "Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase", "aln": "----MASATLGSSSSSASPAVAELCQNTPETFLEASKLLLTYADNILRNPSDEKYRSIRIGNTAFSTRLLPVRGAVECLFEMGFEEG--ETHLIFPKKASVEQLQKIRDLIAIERSSRLDGS--SKKVQFSQHPAA-AKLPLEQSEDPAGLIRHSGNQTGQLPSLPSAPMVVGDSTILKVLQSNIQHVQLYENPVLQEKALTCIPVSELKRKAQEKLFRARKLDKGTNVSDE-----DFLLLELLHWFKEEFFRWVNNIVCSKCGG---ETRSRDEALLPNDDELKWGAKNVENHYCDACQLSNRFPRYNNPEKLLETRCGRCGEWANCFTLCCRALGFEARYVWDYTDHVWTEVYSPSQQRWLHCDACEDVCDKPLLYEIGWGKKLSYIIAFSKDEVVDVTWRYSCKHDEVMSRRTKVKEELLRETINGLNKQRQLSLSESRRKELLQRIIVELVEFISPKTPRPGELGGRVSGSLAWRVARGETGLE-----RKEILFIPSENEKISKQFHLRYDIVRDRYIRVSDNN------INISGWENGVWKMESIFRKVEKDWNMVYLARKEGSSFAYISWKFECGSAGLKVDTVSIRTSSQSFESGSVRWKLRSETAQVNLLGDKNLRSYNDFSGATEVTLEAELSRGDGDVAWQHTQLFRQSLNDSGENGLEIIITFNDL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96IV0-1", "uniprot_id": "NGLY1_HUMAN", "id": "Q96IV0-1", "name": "Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase", "aln": "----MAAAALGSSSGSASPAVAELCQNTPETFLEASKLLLTYADNILRNPNDEKYRSIRIGNTAFSTRLLPVRGAVECLFEMGFEEG--ETHLIFPKKASVEQLQKIRDLIAIERSSRLDGSNKSHKVKSSQQPAASTQLPTTPSSNPSGLNQHTRNRQGQSSDPPSASTVAADSAILEVLQSNIQHVLVYENPALQEKALACIPVQELKRKSQEKLSRARKLDKGINISDE-----DFLLLELLHWFKEEFFHWVNNVLCSKCGG---QTRSRDRSLLPSDDELKWGAKEVEDHYCDACQFSNRFPRYNNPEKLLETRCGRCGEWANCFTLCCRAVGFEARYVWDYTDHVWTEVYSPSQQRWLHCDACEDVCDKPLLYEIGWGKKLSYVIAFSKDEVVDVTWRYSCKHEEVIARRTKVKEALLRDTINGLNKQRQLFLSENRRKELLQRIIVELVEFISPKTPKPGELGGRISGSVAWRVARGEMGLQ-----RKETLFIPCENEKISKQLHLCYNIVKDRYVRVSNNN------QTISGWENGVWKMESIFRKVETDWHMVYLARKEGSSFAYISWKFECGSVGLKVDSISIRTSSQTFQTGTVEWKLRSDTAQVELTGDNSLHSYADFSGATEVILEAELSRGDGDVAWQHTQLFRQSLNDHEENCLEIIIKFSDL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q503I8-1", "uniprot_id": "NGLY1_DANRE", "id": "Q503I8-1", "name": "Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase", "aln": "--------------MPGSQGVLALCENTTEVFLDVSKLLITYADNILRNPNEEKYRSIRIGNPTFSTKLLPVKGAVECLFEMGFEEA--ETHLVFPRSASVEKLRQVRETIAAERDQRLGAS----NTASSPQNASVPPVPAPPPSLSSTASAGPAAAAVPTPAPASIPFTSSSATFQRTVQSNFQHVLVYEDPELQQKALECIPHELLRSRAKERLKQANDADAACSLGEE-----DMLVLDLLQWFKSDFFSWVDNLPCIQCGG---KTQPSG-SLSPSSDDLHWDAGRVENHFCHTCQLSTRFPRYNNPEKLLETRKGRCGEWANCFTLLCRALGLEARYIWDSTDHVWTEVYSQSQRRWIHCDPCENACDKPLLYEVGWGKKLSYILAFSKDQVADVTWRYSCKHPEVLSRRTQVQETWLLHMLNKLNAERQQFLGAERKQQLLQRLLVELVEFISPKSPQPGELGGRMSGSLAWRAARGETGASNAKEDTQENVFTPSESEKESKRFHICYNVTKDCYYRVSNGQ------ETIQGWQKGAWRTENMFRKEEHDWQMVYLARTEGASFGRMSWKFNCAPAGMKMKSASVRVFSQTFHSGTVRWSLSTNETTTEFPGDGELHSFSNVSGGTELIVEAELTGGDGSTSWQHAQLFRQSLKDTEKVLFEVMVEMEKS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KRR5-1", "uniprot_id": "NGLY1_DROME", "id": "Q7KRR5-1", "name": "Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase", "aln": "MVDINLECVHQIEPKTRSAGQQQQERGLKEAYLEAVRILLVLLENILAQPENSMFRTIRQENKAIKEKLLSLPGCERLLEAIGFVRAPSSNAYTLPTEVSLQQVKKYRDALSERRTAWLNGT---------------VSKSPPQQSTTSTTPLFIKPSVEYRHRIAFPRVLRTNNNFLQSLELYSDAVMQYEDNLLLATGRTLIPVEELTEMASEKLIDIQDQIASGERQEKEPCVRDLLLVELVNWFNTQFFQWVNNIPCRVCGS---EESRLRRTEREGD---------IRVEVTVCCGQESKFYRYNDISQLLVSRKGRCGEYANCFTFLCRALDYDARIVHSHFDHVWTEVYSEAQMRWLHVDPSENVIDSPLMYQHGWKRHIDYILAYSRDDIQDVTWRYTNDHQKILHLRKLCGEKEMVQTLDAIRAKRRQNCTADRKLFLSQRNMYEVIGLTLERKPTENELKGRSSGSLSWRQSRGEHTFT------NIFVFNLSATELQKRQLNVRYSCATDTYERYAKEGEHITILDSYKTWQKAQFSSKNIFRKVERDWKMAYLARLEDTDCGEIAWTFDFSKTNLKVKSYNLVFETKTFGDGKISVTVDATDGSASVEN------------ATGFKIVAKLTGGKGDVAWQHTQLFRQSLN-SRDYPFDLQVQLH--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q02890-1", "uniprot_id": "PNG1_YEAST", "id": "Q02890-1", "name": "Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase", "aln": "--------------------MGEVYEKNNIDFDSIAKMLLIKYKDFILS--------------------------------------------KFKKAAPVENIR-------------------------------------------------------------FQNLVHTNQFAQGVLGQSQHLCTVYDNPSWHSIVLETLDLDLIYKNVDKEFAKDGHAEGENIYTDY-------LVKELLRYFKQDFFKWCNKPDCNHCGQNTSENMTPLGSQGPNGEESKFNCGTVEIYKCNRCGNITRFPRYNDPIKLLETRKGRCGEWCNLFTLILKSFGLDVRYVWNREDHVWCEYFSNFLNRWVHVDSCEQSFDQPYIYSINWNKKMSYCIAFGKDGVVDVSKRYILQN---ELPRDQIKEEDLKFLCQFITKRLRYSLNDDEIYQLACRDEQEQIELIRGKTQETKSESVSAASKSSNR-----------------------------------------------------------------------------------------GRESGSADWKAQRGEDGK--------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . ::*: .::: . : ..::::: . : . *:: : . : .:.: . : *: :*:.:*: :** * :: * ** : : .. :. * .:* ***: :** :* *****:.* **: ::.. :.* : . **** * :* **:* *..*: *.* :*. .* :::.* :*:.:* : **: ** .: * * : : : . : .. * * * : : :. . :.. : * . . . *. : . . ", "identical_positions": 57, "similar_positions": 108, "identity": "8.39%" }, { "cls_id": "homologset.agr.RGD:1308519", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CWP8-1", "uniprot_id": "DPOD4_MOUSE", "id": "Q9CWP8-1", "name": "DNA polymerase delta subunit 4", "aln": "MGRKRFITDSYPVVKKREGPPGHSKGELAPELGEDTQSLSQEETELELLRQFDLAWQYGPCTGITRLQRWSRAEQMGLKPPLEVYQVLKAHPEDPHFQCSLWHLYPL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6P6U6-1", "uniprot_id": "Q6P6U6_RAT", "id": "Q6P6U6-1", "name": "", "aln": "MGRKRFITDSYPVVKKREGPPGHNKGELAPELGEDTQSLSQEETELELLRQFDLAWQYGPCTGITRLQRWHRAEQMGLKPPVEVYQVLKTHPEDSRFQCSLWHLYPL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9HCU8-1", "uniprot_id": "DPOD4_HUMAN", "id": "Q9HCU8-1", "name": "DNA polymerase delta subunit 4", "aln": "MGRKRLITDSYPVVKRREGPAGHSKGELAPELGEEPQPRDEEEAELELLRQFDLAWQYGPCTGITRLQRWCRAKQMGLEPPPEVWQVLKTHPGDPRFQCSLWHLYPL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****:*********:****.**.**********:.*. .:**:************************** **:****:** **:****:** *.:***********", "identical_positions": 87, "similar_positions": 16, "identity": "81.31%" }, { "cls_id": "homologset.agr.RGD:1308520", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4AEA3-1", "uniprot_id": "D4AEA3_RAT", "id": "D4AEA3-1", "name": "", "aln": "MWVSWDHLRMLSWLLVFHTLVLPALGVSSLEKPQTNQVSKGLQQL---LGNISQFFEKDILGRDDAFIMVSRKGWG-AEATGCSSKLGRPVDVLVIHHVPGLECHNQTVCSQKLRELQAYHIRN-HWCDVAYNFLVGDDGKVYEGVGWNVQGSHDQGYNNISLGVAFFGTQEGHSPSPVALLAMEALISHAVKKGHLSSKYIQPLLVKSEDCLVPPQKGKQKKAACPHIVPRSAWGARESHCFKMTLPAKYAIILHTAGRTCSQPDECRLLIQDLQSFFMDRLNACDIGYNFLVGQDGGVYEGVGWNNQGSKTDGYNDIALSIAFMGIFTAACPHIVPRSAWGARESHCFKMTL--PAKYAIILHTAGRTCSQPDECRLLIQDLQSFFMDRLNACDIGYNFLVGQDGGVYEGVGWNNQGSKTDGYNDIALS-IAFMGIFTGSSPNAAALQAAQDLIQCAVVKGYLTPNYLLMGHSDVSNTLSPGQALYNIIKTWPHFKH-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q0VB07-1", "uniprot_id": "PGRP4_MOUSE", "id": "Q0VB07-1", "name": "Peptidoglycan recognition protein 4", "aln": "---------MLSWLLVFSILVLLAQGVSSWENPQTDQVSEGLQQL---FGNISQLFEKGILGRDDVFTMVSREEWG-AEAIGCSSKLSRPVDVLVIHHIPGLECHNKTVCSQKLRELQAYHIHN-SWCDVAYNFLVGDDGRVYEGVGWNVQGSHDQGYKNISLGVAFFGTQEGHSPSPVALSAMKGLISYAVKKGHLSSKYIQPLLAKSEDCLVPPQKGKQKK------------------------------------------------------------------------------------------------------------ACPHIVPRSVWGARDSHCSRMTL--PAKYAIILHTAGRTCSQPDECRLLVRDLQSFFMNRLNACDIGYNFLVGQDGGVYEGVGWNNQGSKTDSYNDISLS-ITFMGTFTGSPPNAAALEAAQDLIRCAVVKGYLTPNYLLMGHSDVSNTLSPGQALYNIIKTWPHFKH-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96LB8-1", "uniprot_id": "PGRP4_HUMAN", "id": "Q96LB8-1", "name": "Peptidoglycan recognition protein 4", "aln": "---------MLPWLLVFSALGIQAWGDSSWNKTQAKQVSEGLQYL---FENISQLTEKGLP--TDVSTTVSRKAWG-AEAVGCSIQLTTPVNVLVIHHVPGLECHDQTVCSQRLRELQAHHVHNNSGCDVAYNFLVGDDGRVYEGVGWNIQGVHTQGYNNISLGFAFFGTKKGHSPSPAALSAMENLITYAVQKGHLSSSYVQPLLGKGENCLAPRQKTSLKK------------------------------------------------------------------------------------------------------------ACPGVVPRSVWGARETHCPRMTL--PAKYGIIIHTAGRTCNISDECRLLVRDIQSFYIDRLKSCDIGYNFLVGQDGAIYEGVGWNVQGSSTPGYDDIALG-ITFMGTFTGIPPNAAALEAAQDLIQCAMVKGYLTPNYLLVGHSDVARTLSPGQALYNIISTWPHFKH-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VYX7-1", "uniprot_id": "PGPSA_DROME", "id": "Q9VYX7-1", "name": "Peptidoglycan-recognition protein SA", "aln": "--------------------------------------------------------------------------------------------------------------------MQPVRFGS------PWIMAIG----------------------LVLLLLAFVSAGKSRQRSPAN--------------------------------------------------------------------------------------------------------------------------------------------------------CPTIKLKRQWGGKPSLGLHYQVR-PIRYVVIHHTVTGECSGLLKCAEILQNMQAYHQNELDFNDISYNFLIGNDGIVYEGTGWGLRGAHTYGYNAIGTG-IAFIGNFVDKLPSDAALQAAKDLLACGVQQGELSEDYALIAGSQVISTQSPGLTLYNEIQEWPHWLSNP---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8SXQ7-1", "uniprot_id": "PGPLF_DROME", "id": "Q8SXQ7-1", "name": "Peptidoglycan-recognition protein LF", "aln": "----------MPKTVVVTHPGKPINNEKRFRFELLYFCVILLMVVGLAAGYFMWMMSFSTHSPNKGLHILDRSEWLGEPPSGKYPHLKLPVSNIIIHHTATEGCEQEDVCIYRMKTIQAFHMKSFGWVDIGYNFLVGGDGQIYVGRGWHIQGQHVNGYGAISVSIAFIGTFVNMEPPARQIEAAKRLMDEGVRLHRLQPDYHIYAHRQLSPTESPGQKLFELMQN------------------------------------------------------------------------------------------WPRFTQDPTSLRLLSNETVKIVTRPYWLAQPPIVPLTPLKLPIESVRFVATNTPSCFTQAECTFRVRLLQNWHIESNGYKDINYNFVAAGDENIYEARGWDHSCEPPK--DADELV-VAFIG------PSSSNKKIALELIKQGIKLGHISKNYSLIDDLEKS--------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9GN97-1", "uniprot_id": "PGPLD_DROME", "id": "Q9GN97-1", "name": "Peptidoglycan-recognition protein LD", "aln": "-----------------------------------------------------------MDSSHIAVRVARRSPSPAAVSQSSYGSLGSSQDIHIRVDKEGVASESTPLLAAAQRSIKTSSSLTASVSASSTTPSNCRRNPTLHEDCFNWRSVGLLVMCASALALAAYLLWRQTQTPDFG-------------------------------------------------------------------------------------------------------------------------------------------------------YRLSIVGHGIWSDMELQGRGTLFD-PIGVGTVIFTHTGSNECHDDCPDVLHKLERSHVG-----ELPYNFLVAGDCQVFEAQGWHYRSQYPRDLNGIDSLVMAFVGNFSGRPPIDCQLMAAQALILESLKRRILQPIYQLFVLGSYT------DALQRELRHWPHYASHQTSK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::. . : .* . . : : * . * . * .* :: :: . :: ***: . * ::*. ** . : ::*:* * . * *: .: : * *. . ", "identical_positions": 19, "similar_positions": 37, "identity": "3.77%" }, { "cls_id": "homologset.agr.RGD:1308521", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P97334-1", "uniprot_id": "NKX23_MOUSE", "id": "P97334-1", "name": "Homeobox protein Nkx-2.3", "aln": "------------------MMLPSP--------VTSTPFSVKDILNLEQQ-RHFHGAHLQAELEQHFHSAPCMLATAEGTQFSDAGEEDE---------------EEEGEKLSYLNSLAAAEGHGDSG------------LCPQSYVHTVLRDACSGPKEQEEE----VVSERSQKSCQLKKSLEAAGDCKTSEDGERPKPRSRRKPRVLFSQAQVFELERRFKQQRYLSAPEREHLASSLKLTSTQVKIWFQNRRYKCKRQRQDKSLELGTHAPPPPPRRVAVPVLVRDGKPCVTPSAQTYGSPYGVGAGAYSYNSFPAYGYGNSAAAAAAAAAAAAAAAAYSGSYGCAYPTGGGGGGGGTASAATTAMQPACSATGGGSFVNVSNLGGFGSGGGAQPLHQGAAAGSACTQGTLQGIRAW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZZC9-1", "uniprot_id": "D3ZZC9_RAT", "id": "D3ZZC9-1", "name": "", "aln": "------------------MMIPSP--------VTSTPFSVKDILNLEQQ-RHFHGAHLQAELEQHLHSAPCMLAAAEGTQFSDAGEEDE---------------EEEGEKLSYLNSLAAAEGHGVSG------------LCPQSYVHTVLRDSCSGPKEQEEE----VVSERSQKSCQLKKSLEAAGDCKASEDGERPKPRSRRKPRVLFSQAQVFELERRFKQQRYLSAPEREHLASSLKLTSTQVKIWFQNRRYKCKRQRQDKSLELGTHAPPPPPRRVAVPVLVRDGKPCVTPSAQAYGSPYGVGAGAYSYNSFPAYGYGNSAAAAAAAAAAAAAAAAYSGSYGCAYPTGGGGGGGGAASAATTAMQPACSATGGGSFVNVGNLGGFGSGGGAQPLHQGAAAGAACAQGTLQGIRAW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8TAU0-1", "uniprot_id": "NKX23_HUMAN", "id": "Q8TAU0-1", "name": "Homeobox protein Nkx-2.3", "aln": "------------------MMLPSP--------VTSTPFSVKDILNLEQQHQHFHGAHLQADLEHHFHSAPCMLAAAEGTQFSDGGEEDE---------------EDEGEKLSYLNSLAAADGHGDSG------------LCPQGYVHTVLRDSCSEPKEHEEEP--EVVRDRSQKSCQLKKSLETAGDCKAAEESERPKPRSRRKPRVLFSQAQVFELERRFKQQRYLSAPEREHLASSLKLTSTQVKIWFQNRRYKCKRQRQDKSLELGAHAPPPPPRRVAVPVLVRDGKPCVTPSAQAYGAPYSVGASAYSYNSFPAYGYGNSAAAAAAAAAAAAAAAAYSSSYGCAYPAGGGGGGGGTS-AATTAMQPACSAAGGGPFVNVSNLGGFGSGGSAQPLHQGTAAGAACAQGTLQGIRAW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P22711-1", "uniprot_id": "TIN_DROME", "id": "P22711-1", "name": "Muscle-specific homeobox protein tinman", "aln": "MLQHHQQQAQSGGYYDHYTQSPSPGSLTNADALNTTPFSVKDILNMVNQTEAYEGSYGHIDGAATASALFAAGEYQNPHQYLNHQQHQQSELPIPQQQLHHQHLDDGATTSSSLSPLLPPPPHQLYGGYQDYGMPAHMFQHHHGHPHQSFQHSASAYNMSASQFYAGASATAYQTPATYNYNYAGSGEVYGGATPSAVGIKSEYIPTPYVTPSPTLDLNSSAEVDSLQAPTQKLCVNPLSQRLMETASNSSSLRSIYGSDEGAKKKDNSQVTSSRSELRKNSISGNSNPGSNSGSTKPRMKRKPRVLFSQAQVLELECRFRLKKYLTGAEREIIAQKLNLSAT-QVKIWFQNRRYKSKRGDIDCEGIAKHLKLKSE---PLDSPTSLPPPIPNHVMWPPTMQQSQQQQQHHAQQQQMQHM", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *** :.:**********: :* . :.*:: : : : . : *: : :.:: :: . . * *..* .. * * :.: * ::.:.* : .: . *... : . :*: . . :*. * .: : .::*: : : :..:: : . : .. . * . : .*. : . :. . *: ::. . *. . :...: * : : * : : : :.* * : : . : . * . * : .: .: . .* .. * : :. * :: ", "identical_positions": 41, "similar_positions": 120, "identity": "9.76%" }, { "cls_id": "homologset.agr.RGD:1308523", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZHH5-1", "uniprot_id": "D3ZHH5_RAT", "id": "D3ZHH5-1", "name": "", "aln": "MDSKTCESKKEDLLS-SGVISKGGSSSPFFVTSTHGAIIENTSSAGTLTQIPFFPKYEVELDSPRKSTSYPGKEHIERVLEEYSQQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEELRNQLQNTVHELEAAKSLKEDMLKDSSTQIEQLRKLMLSHEGVLQDIRSVLVDFEEASGKKICEHDSMSTMHFRSLGSAISKILRELDTEISFLKGRIFPVEDQLETLKSESQNKIELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSVQSQLEIIQEQARNQNSMYMRQLSDLESTVSQLRSELRETKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKNECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMNLESSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEALRLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRKLELQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIRQERDQLLNEVKTSRTELNNLSEDYEVLKRNFRNKSEEMESTTNRLKMQLKSAQSELEQTRNTLKTMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKVQFLEEAVTSANKEKHFLKEEKSKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRLKLQHTLDVKELQGPGYTSNSSMKPRLLQPASVARSHSNVPSSQSTASFLSHHSLKTNTLKEDPTRDLKQLLQELRSVINEEPAMPLSKTEEE--TPSLGALEDRVRDCITDSSLRSELCHRSNNSLRESTEGSKSSETLSREPVALHPGDLEDPSSCFTFTSTASPSVKISASRSFNSSPKKSPVHSLLTSSAEESVGSTPQYRSAKPVHSSNSAKDSQSPSLETTGKTCRKLQNRLESLQTLVEDLQLKNQAMSSMIRNQEKRIQKVKDQEKMLLK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CDI6-1", "uniprot_id": "CD158_MOUSE", "id": "Q8CDI6-1", "name": "Coiled-coil domain-containing protein 158", "aln": "MESKACESKNEDLLP-SGITSKGGSSSPFFVTSTHGTIIENTSSTGTLTQMPFFPKYEVELDSPRKSTPYPGKEHIERVLEEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEESRNQLQNTVRELEAAKCLKEDMLKDSSTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKICEHDSMSTMHFRSLGSAISKILRELDTEISFLKGRIFPVEDQLETLKSESQNKIELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSVQSQLEIIQEQARNQNSMYMRQLSDLESTVSQLRSELRESKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMNLESSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRKLELQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIRHERDQLLNEVKTSRTELNHLSEDYEVLKRNFRNKSEEMESTTNRLKMQLKSAQSELEQTRNTLKTMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKVQFLEEAVTSANKERHFLKEEKSKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDK----FAECQDIIQRQEQESVRLKLQHTLDVKELQGPGYTSNSSVKPRLLQPASVTRSHSNIPSSQSTTSFLSHHSIKTNTPKEDPTRDLKQLLQELRTVINEEPAMALSKTEEDGRTPSLGALEDRVRDCITESSLRAELCHRSNNSLRESTEGSKSSETLSREPVPLHPGDLEDPSSCFTFTSTASPSGKMSASRSFSSSPKKSPVHSLLTSSAEESVNSTPQYRSTKPIHSPTSAKDSQSPSLETTGKTCQKLQNRLESLQTLVEDLQLKNQAMSSMIRNQEKRIQKVKDQEKMLLK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5M9N0-1", "uniprot_id": "CD158_HUMAN", "id": "Q5M9N0-1", "name": "Coiled-coil domain-containing protein 158", "aln": "MESKAWESNNEDLLSSSGVTSNGGSSSSFFVSSIRGTIIENTSSAGTLTQVPFFPKYEVELDSPRKIIPSPGKEHFERVLEEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHELEAAKCLKEDMLKDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKICEHDSMSTLHFRSLGSAISKILRELDTEISYLKGRIFPVEDQLEALKSESQNKIELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQMEIIQEQARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKTEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDNRNMEVQRLEALLKALKSECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTISDLTTSLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEALKLQMTEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRMELKELKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRSELNNLSEEYEVLKRNFRNKSEEMEMTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKSKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVTNMEVALDKASLQFAECQDIIQRQEQESVRLKLQHTLDIKELQGPGYTSNSSLKPRLLQPASVTRSHSNVPSSQSTASFLSHHSTKANTLKEDPTRDLKQLLQELRSVINEEPAVSLSKTEEDG-RTSLGALEDRVRDCITESSLRSDMCHRSNNSLRDSTEGSKSSETLSREPVTLHAGDREDPSGCFTFTSAASPSVKNSASRSFNSSPKKSPVHSLLTSSVEGSIGSTSQYRSAKPIHSSDSVKDSQSPPIETTGKTCRKLQNRLESLQTLVEDLQLKNQAMSSMIRNQEKRIQKVKDQEKMLLK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:**: **::****. **: *:*****.***:* :*:*******:*****:*************** . *****:********:********************************************************: ********:******.*********.********:*********:***:********************:*********************:*************:***********************************************:***:**********************************:******* ******************************************************************************:**************:*.*************************************************.*******:****:**************************************************:***:********************************************::**:*:******************************************::*************:***:***:**************** ***:********************:********************************:******:*.****:******************************************:******** *************************:*************:**********:*****:******:******* *:** ****************:*******:.******: .**************:****:::*********:****************.**.** ****.******:**** * ******.***************.* *:.**.****:**:**. *.******.:*******:**********************************************", "identical_positions": 1005, "similar_positions": 85, "identity": "90.22%" }, { "cls_id": "homologset.agr.RGD:1308524", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZUD0-1", "uniprot_id": "D3ZUD0_RAT", "id": "D3ZUD0-1", "name": "Protein ECT2", "aln": "MADDSVLPSPTEITSLADTSVFDSKVTETSKENLCMVSTSNVDEEMPQVEARVVVVQEAGKQEELLKALKTVKIMEVPVIKIKESCPGKSDEKLIKSIINMEIKVPCVKMDSMEEFGSLDSPEFENIFVVTDFQTSVFNDLYKADCRIVGPPVILNCAQMGEPLPFSCRPLYCTSMLNLVLCFTGFRKKEELVKLVTLVHHMGGVIRKECNSKVTHLVANCTQGEKFRVAVSLGTPIMRPGWIYEAWERRNEQCFCAADDDFRNEFKVPPFQDCILSFLGFSDEEKHSMEEMTEMQGGTYLPVGDERCTHLIVDEN------------------------------------------------------------------------------TVKELPFEPSKKLFVVKQEWFWG-----------------------------------------------------------------------------------------------------------------SIQMDARAGETMYLYEKANTPELKKSVSLLSLSTPNSNRKRRR------------------------------------LKESLAQLSRETDLSPFPPRKR------------------------------------------------------------------------------------------PSAEHSLSIGSLLDISNTPDSSIHYGETPKSCAKSSRS-----------------------------------------------------------------------------------------------------------------------------------------STPVPPKQSARWQVAKELYQTESNYVNILATIIQLFQVPLEEEGQRGGPILAPEEIKTIFGSIPDIFDVHMKIKDDLEDLIANWDESRSIGDIFLKYSKDLVKTYPPFVNFFEMSKEMIIKCEKQKPRFHAFLKINQAKPECGRQSLVELLIRPVQRLPSVALLLNDLKKHTADENPDKSTLEKAIGSLKEVMTHINEDKRKTEAQKQIFDVVYEVDGCPANLLSSHRSLIQRVETVSLGEHPCDRGEQVTLFLFNDCLEIARKRHKVIGTFRSPHDRTRPPASLKHIHLMPLSQIKKVLDIRETEDCHNAFALLVRPPTEQANVLLSFQMTSEELPKESWLKMLCRHVANTICKADAENLMYVTDPESFEVNTKDMDS-TLSRASRAIKKTSKKVTRAFSFSKTP---KRALRMALSSSH-SSEGRSPPSSGKLAVSRLSSTSSLAGIP----------SPSLVSLPSFFERRSHTLSRSTTHLI---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q07139-1", "uniprot_id": "ECT2_MOUSE", "id": "Q07139-1", "name": "Protein ECT2", "aln": "MADDSVLPSPSEITSLADSSVFDSKVAEMSKENLCLASTSNVDEEMPQVEARVIMVQDAGKQEELLKALKTIKIMEVPVIKIKESCPGKSEEKLIKSIINMEMKVPCVKMDSMEEFESLDSPEFENIFVVTDFQNSVFNDLYKADCRIVGPPVILNCAQRGEPLPFSCRPLYCTSMLNLVLCFTGFRKKEELVKLVTLVHHMGGVIRKECNSKVTHLVANCTQGEKFRVAVSLGTPIMKPEWIYKAWERRNEQCFCAAVDDFRNEFKVPPFQDCILSFLGFSDEEKHSMEEMTEMQGGSYLPVGDERCTHLIVEEN------------------------------------------------------------------------------TVKDLPFEPSKKLFVVKQEWFWG-----------------------------------------------------------------------------------------------------------------SIQMDARAGETMYLYEKANTPELKKSVSLLSLSTPNSNRKRRR------------------------------------LKETLAQLSRETDLSPFPPRKR------------------------------------------------------------------------------------------PSAEHSLSIGSLLDISNTPESSIHYGETPKSCAKSSRS-----------------------------------------------------------------------------------------------------------------------------------------STPVPPKQSARWQVAKELYQTESNYVNILATIIQLFQVPLEEEGQRGGPILAPEEIKTIFGSIPDIFDVHMKIKDDLEDLIANWDESRSIGDIFLKYAKDLVKTYPPFVNFFEMSKEMIIKCEKQKPRFHAFLKINQAKPECGRQSLVELLIRPVQRLPSVALLLNDLKKHTADENPDKSTLEKAIGSLKEVMTHINEDKRKTEAQKQIFDVVYEVDGCPANLLSSHRSLVQRVETVSLGEHPCDRGEQVTLFLFNDCLEIARKRHKVIGTFRSPHDRTRPPASLKHIHLMPLSQIKKVLDIRETEDCHNAFALLVRPPTEQANVLLSFQMTSEELPKESWLKMLCRHVANTICKADAENLMYVADPESFEVNTKDMDS-TLSRASRAIKKTSKKVTRAFSFSKTP---KRALRMALSSSH-SSEGRSPPSSGKLAVSRLSSTSSLAGIP----------SPSLVSLPSFFERRSHTLSRSTTHLI---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H8V3-1", "uniprot_id": "ECT2_HUMAN", "id": "Q9H8V3-1", "name": "Protein ECT2", "aln": "MAENSVLTSTTGRTSLADSSIFDSKVTEISKENLLIGSTSYVEEEMPQIETRVILVQEAGKQEELIKALKTIKIMEVPVIKIKESCPGKSDEKLIKSVINMDIKVGFVKMESVEEFEGLDSPEFENVFVVTDFQDSVFNDLYKADCRVIGPPVVLNCSQKGEPLPFSCRPLYCTSMMNLVLCFTGFRKKEELVRLVTLVHHMGGVIRKDFNSKVTHLVANCTQGEKFRVAVSLGTPIMKPEWIYKAWERRNEQDFYAAVDDFRNEFKVPPFQDCILSFLGFSDEEKTNMEEMTEMQGGKYLPLGDERCTHLVVEEN------------------------------------------------------------------------------IVKDLPFEPSKKLYVVKQEWFWG-----------------------------------------------------------------------------------------------------------------SIQMDARAGETMYLYEKANTPELKKSVSMLSLNTPNSNRKRRR------------------------------------LKETLAQLSRETDVSPFPPRKR------------------------------------------------------------------------------------------PSAEHSLSIGSLLDISNTPESSINYGDTPKSCTKSSKS-----------------------------------------------------------------------------------------------------------------------------------------STPVPSKQSARWQVAKELYQTESNYVNILATIIQLFQVPLEEEGQRGGPILAPEEIKTIFGSIPDIFDVHTKIKDDLEDLIVNWDESKSIGDIFLKYSKDLVKTYPPFVNFFEMSKETIIKCEKQKPRFHAFLKINQAKPECGRQSLVELLIRPVQRLPSVALLLNDLKKHTADENPDKSTLEKAIGSLKEVMTHINEDKRKTEAQKQIFDVVYEVDGCPANLLSSHRSLVQRVETISLGEHPCDRGEQVTLFLFNDCLEIARKRHKVIGTFRSPHGQTRPPASLKHIHLMPLSQIKKVLDIRETEDCHNAFALLVRPPTEQANVLLSFQMTSDELPKENWLKMLCRHVANTICKADAENLIYTADPESFEVNTKDMDS-TLSRASRAIKKTSKKVTRAFSFSKTP---KRALRRALMTSHGSVEGRSPSSNDKHVMSRLSSTSSLAGIP----------SPSLVSLPSFFERRSHTLSRSTTHLI---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8IQ97-1", "uniprot_id": "Q8IQ97_DROME", "id": "Q8IQ97-1", "name": "", "aln": "------------------------------MEMETIEEQSKCEMSITTLPTRICLVGGVGQDADTLQAAESFGLPIVTSDTGLDILG--------------------------------ESSDWRTFYVLDDFEGASFEAIHKQKECILGPPALKYAAEMKQTLGQNSRPIYNYAMRGVVTCFTGIRKKDELTKLVNLIHSMGGCIKKDLNTKTTHLICNHSGGEKYQYAKTFRLTVVRPAWVFAAWADRNSLEFDATQENFTKTHRLKAFEGQKICFFGFPVEEHQHMVDVLLENGGVCAELDDPECSHVVMPNTGAVFTSTSTSTDTNPSTLINPPESQVPGSSSASQAGEEEQRKAEHLEQAEIKKMEYSHAETDNGMSLDIDQEQKENQGIEDEDDIHFDERLFVEAADIINHGEDQLPESDEEDLEEEQKPKVEEVLKEQEVEEDVQASTPKTSKIRTSLKAATPLSSPEMDGIALDFESTTQNISPILKAIDECDLETDDLPPSENDLKRKRESFDNVSLMSVDSFALPASTKKPKLIRTGSISRTLRRSVSFVAEPLMKTLRPRRSSVADASSFVGSEAADNSICSLASSINLTLNDSIRKPVKEKLRSFCGRITRSSSRRHDRGVDGTPECTTLLDSGFKTPKAPKLRSTATPKTAKRLFGPVSGVVSALTLTNPSTPTPNPNPNTNCTATLDVNDTSIHTFAFCAAAVTPAMPPSSSSSSSSPILSTSIAVHSSVQVIKSPEESTTRRNSPAPIEEPMAMVVDEHTTLTKPEPKNNHTHILKSDWFWYTIQNGYANEMDYLFGDYLDSITNTPNTDRRDSLPISFNKRKRKRFSQRIQLEGTPLGSGKRRSSVSDAGLLSVSNSLFDCTTSPDKLESDKLLHAEPEASDATPAKKSMRFNHFMDFYTTESNYVGILDTILNLFKNKLEELAETNDPLLNKSEIKTIFGNFLPIHEVHQSMLEHLRKLHANWREDCLIGDIIIQHRDELIKAYPPYVNFFEQMKEQLQYCDREYPRFHAFLKINQTKPECGRQGLQDLMIRPVQRLPSISLLLNDILKHTTSGNADHGRLEEALKAIKQVTLHINEDKRRTESRMAIFDIFNDIEGCPAHLVSSNRSFILKCEVNELSDSLSGRGDSLVLYLFSDSIELCKRRSKGFNTAKSPS----TAKTHKHLKLISLNTIRLVIDISDSP---RAFGLLLR---GDKEKLYTFTISDEETDKSVYVKKLCNQIAAHTCRTDADKLLICRTSQELEVDISDVNVSTLSKAFKLAAKTRLKVGRAFSFNKTPNKLKRAVSTMMTSPFGSTNSLTPAS--QLAQMRLASCTNINEVDDEDCASMRSSSPSTQSEMLVVPPLSVQPTRKNKAVVGRI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 289, "similar_positions": 320, "identity": "20.87%" }, { "cls_id": "homologset.agr.RGD:1308525", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZIL6-1", "uniprot_id": "D3ZIL6_RAT", "id": "D3ZIL6-1", "name": "", "aln": "MLRALPRAL----RLRRPWMSPGARGCAAHASTRTP-EIQVQALTGPNQGITEILMNRPHARNALGNVFVSELLEALAQLREDQQVRVLLFRSAVKGVFCAGADLKERERMSAAEVGTFVQRLRGLMSEIAAFPAPTIAAMDGFALGGGLELALACDLRIAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLNGVQAHELGLVNHAVAQNEEGDAAYHRALALAQEILPQAPIAVRLGKVAIDRGMEVDIASGMAIEHMCYAQNIPTQDRLEGMAAFREKRPPKFVGK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TLP5-1", "uniprot_id": "ECHD2_MOUSE", "id": "Q3TLP5-1", "name": "Enoyl-CoA hydratase domain-containing protein 2, mitochondrial", "aln": "MLRVLPRAL----RLPCSWRFSGARDCASHATTRTP-EIQVQALTGPNQGITEILMNRPNARNALGNVFVSELLEALAQLREDQQVRVLLFRSAVKGVFCAGADLKEREQMSDVEVGTFVQRLRGLMSEIAAFPVPTIAAMDGFALGGGLELALACDLRIAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLNGAQARELGLVNHAVAQNEEGNAAYHRALALAQEILPQAPIAVRLGKVAIDRGMEVDIASGMAIEQMCYAQNIPTQDRLEGMAAFREKRAPKFVGK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86YB7-1", "uniprot_id": "ECHD2_HUMAN", "id": "Q86YB7-1", "name": "Enoyl-CoA hydratase domain-containing protein 2, mitochondrial", "aln": "MLRVL--------CLLRPWRPLRARGCASDGAAGGS-EIQVRALAGPDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSEAEVGVFVQRLRGLMNDIAAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLGLVNHAVAQNEEGDAAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMAAFREKRTPKFVGK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PM54-1", "uniprot_id": "A0A8M1PM54_DANRE", "id": "A0A8M1PM54-1", "name": "", "aln": "MAAARGVFAGPIKRLLPRGSFTQTRSWCSNGSVSDKKEVRLNRLEGEDNGIVEVLMCRERARNSLGHVFVGQMRDLVSSLQHDSAVRVLVFRSLIPGVFCAGADLKERAQMSNAEAELFVHGLRSLMNDIAALPMPTIAAVDGFALGGGLELALACDLRTAAHCAQMGLIETTRGLLPGAGGSQRLPRTVGFAVAKELIFTGRRVGGEQAVNLGLVNRSVPQNQTGDAAHREALSLAREILPQAPIAVRMAKVAMNRGAEVDISSGMAIEGMCYARLIPTRDRQEGMAAFIEKRPPRYTGE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z934-1", "uniprot_id": "A1Z934_DROME", "id": "A1Z934-1", "name": "Methylglutaconyl-CoA hydratase, mitochondrial", "aln": "MSMLIKRASGLARQLARP--LVASRNLASAAPYGDGTEVLVERLDGARQGISVIGLNRPAAKNSFSRGMVETFNDVLEDIKKDNGSRVVVLRSLSPGIFCAGADLKERKGMTPEEATEFVKELRGLLIAIEQLPMPVIAAVDGAALGGGLEMALACDIRTAASDTKMGLVETRLAIIPGAGGTQRLPRILSPALAKELIFTARVFNGAEAKDLGLVNHVVKQNETQDAAYQQALKLAEEILPNGPVGVRMAKLAIDKGMQVDLATGYSIEEICYSQVIPTKDRLEGLAAFAEKRKPVYKGE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * :*. .: .. *: :. * * :** : : * *:*::.. :* : : : .::.* **:::** *:********** *: *. **: **.*: * :* *.***:** *******:*****:* ** : ***:** .::*****:***** :. *:*******.* ..* :* *****: * **: :**::.* **.****:.*:.**:.*:*:::* :**:::* :** :**:: ***:** **:*** *** * : *:", "identical_positions": 129, "similar_positions": 81, "identity": "42.86%" }, { "cls_id": "homologset.agr.RGD:1308526", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QWK4-1", "uniprot_id": "CD5L_MOUSE", "id": "Q9QWK4-1", "name": "CD5 antigen-like", "aln": "MAPLFNLMLAILSIFVGSCFSESPTKVQLVGGAHRCEGRVEVEHNGQWGTVCDDGWDRRDVAVVCRELNCGAVIQTPRGASYQPPAS-EQRVLIQGVDCNGTEDTLAQCELNYDVFDCSHEEDAGAQCENPDSDLLFIPEDVRLVDGPGHCQGRVEVLHQSQWSTVCKAGWNLQVSKVVCRQLGCGRALLTYGSCNKNTQGKGPIWMGKMSCSGQEANLRSCLLSRLENN-CTHGEDTWMECEDPFELKLVGGDTPCSG------RLEVLHKGSWGSVCDDNWGEKEDQVVCKQLGCGKSLHPSPKT------RKIYGPGAGRIWLDDVNCSGKEQSLEFCRH----RLWGYHDCTHKEDVEVICTDFDV--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43866-1", "uniprot_id": "CD5L_HUMAN", "id": "O43866-1", "name": "CD5 antigen-like", "aln": "MALLFSLILAICTRPG---FLASPSGVRLVGGLHRCEGRVEVEQKGQWGTVCDDGWDIKDVAVLCRELGCGAASGTPSGILYEPPAEKEQKVLIQSVSCTGTEDTLAQCEQE-EVYDCSHDEDAGASCENPESSFSPVPEGVRLADGPGHCKGRVEVKHQNQWYTVCQTGWSLRAAKVVCRQLGCGRAVLTQKRCNKHAYGRKPIWLSQMSCSGREATLQDCPSGPWGKNTCNHDEDTWVECEDPFDLRLVGGDNLCSG------RLEVLHKGVWGSVCDDNWGEKEDQVVCKQLGCGKSLSPSFRD------RKCYGPGVGRIWLDNVRCSGEEQSLEQCQH----RFWGFHDCTHQEDVAVICSG-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1M8T7-1", "uniprot_id": "F1M8T7_RAT", "id": "F1M8T7-1", "name": "", "aln": "MLPWFLLLICGAAQFSVNKIVFSIQLDEMLS--LPCEPAGNPVSDVSLKTKPPGEWVMEGNKLVLICSVANTTENITYLWYRGALGLNLEKKTLPSITAEFEISEVKQSDVD--QYYCAADNGHGPVLSELVNINVRVPVSRPVLTFVDTGT-QAVLGDLVELHCKALRGSPPIFYQFYHENIILGNSSDHSGGGASFNFSLTAEHSGNFSCEASNGQGVQR-SEVVALNLTGLSLVPTVNGIGNLSSGLTGWLIGCLGPIATVLIFCYWLKRKIGRQSDDPLRSPP-QTVLQESNYHNSPDPGHPEPVYENVNAVSGDEVYSLVYHTQQELGPTAAQHVSTHGASESFQLSSGIYSKPRINIVYVDYEDTM", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * *::. : : * .::. ** : . . * . * .. :: ..:. . . . :: : .: . . : *.: : : *: ::. *. .: . :* . : . :. : . : . * :. .:: *.: . . . .::**.. :. . * . . :: . :. *.* * * : * * .** . *.* :: . :* *. . * . : . . * : . . * : . : : :: . ", "identical_positions": 32, "similar_positions": 104, "identity": "8.6%" }, { "cls_id": "homologset.agr.RGD:1308527", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GBB7-1", "uniprot_id": "A0A8I6GBB7_RAT", "id": "A0A8I6GBB7-1", "name": "", "aln": "MEGRGARAARGSAAAADTAAAADTAAAAATAAAALTPPTMDSFDLALLQEWDLESLWGEDILSQRNDSLVLEFQASASRCRSVYEPDRNALRRKERERRSQE----TQQDSGGFNSGYSLFSEPYKTNKGDELSNRIQ---NTLGNYDEMKDFLTDRSNQS--HLVGVPKPGVPQTPVNKIDDHFVAESRAQPQPSSVCSTASSTPAAVPVQQSKRGTMGWQKAGHPPSDGQQRAAQQGSLRTLLGDGVGRQQTRAKQVCNVETGLQTQERPPAMAAKHSGGGHCVQNFP----PSLASKPSLGQQK-------PTAYVR-PMDGQDQAPDESPKLKSSTETAVHCTAYRGVPAGKPESARAKGKLAKFSIPKQGEENRSGETNSCVEEIIREMTWLPPLSAIQAPAKVEPSKFPFP-----------------------------------------------------------------NKDSQLVSSGHSNPKKADAEPESPDNGTSNTSTLEDDLKLSSDDEEGEQQAAQRTVLRALADSSVVQQTNCRGSAPSSKG--------------SSSSSGGSSSSSDSESTSGSDSETESSSSESESEGSKPPHCS-----SPEAEPASSNKWQLDKWLNKVNPHKPPILIQN----------------------------------------------------------------------------------------------------------------ESHGPERNQYYTP-VKDEGQDCGKLPEICQASLRDKELKTACKEEQRPRTANKVPGSKSVKQKSPP--AAVAVTAAAPPPAVPSAPTESAPAPTRR----------------SAGKKPTRRTERTSAGDSANCHRPEEPVAPDALGASVVGPLEPPKTRPCGNSRTGHRKELRSSVTCEKRRTRGLSRIVPKSKEFIETESSSSSSSSDSDLESEQEEYILSKAP-----STTGSEQRLKEATSNNSSSSNSSSSSSS-SSSSSSSTSRASVGSINARTTSDIAKELEEQFYTLVPFGRNEL---------------------------------------------------------------------------------------------------------------------LSPLKDSDEVRSLWVKIDLTLLSR-----------IPEHLSQEPGVLSAPAAKDTDSTPASHALDTPAEKTLP-KSKRKRKCDNEDDYREIKKAQGKKEGASRLAASTNNTFSGSHCNVSINSLAIPINKNEKMLRSPSSPLSDACKHKYSSEDVTS------------SSRPHGNGLLTSVSSNKEPKAESQLQSHAGDLTKISHNSSENGILHSKSRPQTEPWSPGSNG----------------------------HRDCKRQKLIFDDMPRSADYFMREAKRMKHKADAMVEKFGKALNYAEAALSFIECGNAMEQGPMESKSPYTMYSETVELIRYAMRLKTHSGPNATP-----EDKQLAALCYRCLALLYWRMFRLKRDHAVKYSKALIDYFKNSSKAAQAPSPWGSSGKSTGSPSPMSPNPSPASSVGSQGSLSSSSGLSPSTIVSIPQRIHQMAANHVSITNSILHSYDYWEMADNLAKE--NREFFNDLDLLMGPVTLHSSMEHLVQYSQQGLHWLRSSTHLS-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P51827-1", "uniprot_id": "AFF3_MOUSE", "id": "P51827-1", "name": "AF4/FMR2 family member 3", "aln": "---------------------------------------MDSFDLALLQEWDLESLWGEDILSQRNDSLVLEVQASASRCRSVYEPDRNALRRKERERRSQE----TQQDSGSFNSGYSLFSEPYKTNKGDELSNRIQ---NTLGNYDEMKDFLTDRSNQS--HLVGVPKPGVPQTPVNKIDEHFGAESRAQPQPSTVCSTASSTPAAVPVQQGKRGAMGWQKAGHPPSDGQQRAAQQGSLRTLLGDGVGRQQTRAKQVCNMETGLQTQERPPAMAAKHGGSGHCVQNFP----PSLASKPSLVQQK-------PTAYVR-PMDGQDQAPDESPKLKSSTETAVHCTAYRGVPANKPESARAKAKLAKFSIPKQAEESRSGENNSCVEEIIREMTWLPPLSAIQAPAKVEPSKFPFP-----------------------------------------------------------------NKDSQLVSSGHSNPKKADAEPGSPDNGASNTSTLEDDLKLSSDDEEGEQQAAQRTALRALADSSVVQQTNCRGSAPSSKGGG------------SSSSSGGSSSSSDSESTSGSDSETESSSSSSESEGSKPPHCS-----SPEAEPASSNKWQLDKWLNKVNPHKPPILIQN----------------------------------------------------------------------------------------------------------------ESHGPERNQYYTPPVKDEGQDCGKLPEICQASLRDKELKTTCKEEQRPRTANKAPGSKSVKQKSPP--AAVAVTAAALPPAVPSAPTESAPAPTRR----------------SAGKKPTRRTERTSAGDGANCHRPEEPVAPDTLGASVVGPLEPPKTRPCGNNRTGHRKELRSSVTCEKRRTRGLSRIVPKSKEFIETESSSSSSSSDSDLESEQEEYVLSKAP-----TTTGSEQRLKEAASSNNNSN------------SNSSTSRASVGSINARTTSDIAKELEEQFYTLVPFGRNEL---------------------------------------------------------------------------------------------------------------------LSPLKDSDEVRSLWVKIDLTLLSR-----------IPEHLSQEPGVLSAPSAKDTDSAPASHALDAPAEKTLP-KSKRKRKCDNEDDYREIKKVQGRKESASRLAASTNNTLSGNHCNVNVNSLAIPINKNEKMLRSPTSPLSDTCKHKYASEDLTS------------SSRPHGNGLLTSASSNKEPKAESQLQTIAGDLTKASHNSSENGTLHSKSRPQTEPWSPGSNG----------------------------HRDCKRQKLIFDDMPRSADYFMREAKRMKHKADAMVEKFGKALNYAEAALSFIECGNAMEQGPMESKSPYTMYSETVELIRYAMRLKTHSGPNATP-----EDKQLAALCYRCLALLYWRMFRLKRDHAVKYSKALIDYFKNSSKAAQAPSPWGSSGKSTGSPSPMSPNPSPASSVGSQGSLSSSSGLSPSTIVSIPQRIHQMAANHVSITNSILHSYDYWEMADNLAKE--NREFFNDLDLLMGPVTLHSSMEHLVQYSQQGLHWLRSSVHLS-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P51826-1", "uniprot_id": "AFF3_HUMAN", "id": "P51826-1", "name": "AF4/FMR2 family member 3", "aln": "---------------------------------------MDSFDLALLQEWDLESLC-------------------------VYEPDRNALRRKERERRNQE----TQQDDGTFNSSYSLFSEPYKTNKGDELSNRIQ---NTLGNYDEMKDFLTDRSNQS--HLVGVPKPGVPQTPVNKIDEHFVADSRAQNQPSSICSTTTSTPAAVPVQQSKRGTMGWQKAGHPPSDGQQRATQQGSLRTLLGDGVGRQQPRAKQVCNVEVGLQTQERPPAMAAKHSSSGHCVQNFP----PSLASKPSLVQQK-------PTAYVR-PMDGQDQAPDESPKLKSSSETSVHCTSYRGVPASKPEPARAKAKLSKFSIPKQGEESRSGETNSCVEEIIREMTWLPPLSAIQAPGKVEPTKFPFP-----------------------------------------------------------------NKDSQLVSSGHNNPKKGDAEPESPDNGTSNTSMLEDDLKLSSDEEENEQQAAQRTALRALSDSAVVQQPNCRTSVPSSKGSS------------SSSSSGSSSSSSDSESSSGSDSETESSSS--ESEGSKPPHFS-----SPEAEPASSNKWQLDKWLNKVNPHKPPILIQN----------------------------------------------------------------------------------------------------------------ESHGSESNQYYNP-VKEDVQDCGKVPDVCQPSLREKEIKSTCKEEQRPRTANKAPGSKGVKQKSPPAAVAVAVSAAAPPPAVPCAPAENAPAPARR----------------SAGKKPTRRTERTSAGDGANCHRPEEPAAADALGTSVVVPPEPTKTRPCGNNRASHRKELRSSVTCEKRRTRGLSRIVPKSKEFIETESSSSSSSSDSDLESEQEEYPLSKAQTVAASASSGNDQRLKEAAANG------------------GSGPRAPVGSINARTTSDIAKELEEQFYTLVPFGRNEL---------------------------------------------------------------------------------------------------------------------LSPLKDSDEIRSLWVKIDLTLLSR-----------IPEHLPQEPGVLSAPATKDSESAPPSHTSDTPAEKALP-KSKRKRKCDNEDDYREIKKSQGEKDSSSRLATSTSNTLSANHCNMNINSVAIPINKNEKMLRSPISPLSDASKHKYTSEDLTS------------SSRPNGNSLFTSASSSKKPKADSQLQPHGGDLTKAAHNNSENIPLH-KSRPQTKPWSPGSNG----------------------------HRDCKRQKLVFDDMPRSADYFMQEAKRMKHKADAMVEKFGKALNYAEAALSFIECGNAMEQGPMESKSPYTMYSETVELIRYAMRLKTHSGPNATP-----EDKQLAALCYRCLALLYWRMFRLKRDHAVKYSKALIDYFKNSSKAAQAPSPWGASGKSTGTPSPMSPNPSPASSVGSQGSLSNASALSPSTIVSIPQRIHQMAANHVSITNSILHSYDYWEMADNLAKE--NREFFNDLDLLMGPVTLHSSMEHLVQYSQQGLHWLRNSAHLS-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AW05-1", "uniprot_id": "A0A8M3AW05_DANRE", "id": "A0A8M3AW05-1", "name": "", "aln": "---------------------------------------MPTFHGSKGKLASVCFMLQHASQDMTQSWPYQPPPGEGGTQHFLYSHSKEGKQPSGRQRHARDGVSMRMPSRPLVAPHKSMLADDLKLSSDEDDKDEGS---EQTTSWADNDRLSTQHQQQQQQHHTHTHAGRVRHSSSGSSGTDRSSDWESSSQRSRSPSPGAHTRCGTPTQQRTLNCSTETESPPSTHWQLDRWLEKVPKKHQSTDYNPGGGHRQSAKSDCDRGPSPGRYWSRESESRRDYSPCGSQVPS---PKFDYSPRNSPHP-------SPGYSPCPSPGNSLVQSPVPSVCPSPGDSLQGSRSPSPLPTHPPRSPSPSLLSKAVPSQGIYSQVQTSQQESPRHISRPTVASNSGHHPKVRPWVPPDHNANQ-----------------------------------------------------------------RKELRAKDSRSKDSQSKDSRPGPQHQPFNSKHGSTERSHKDFTHKPEAKNSESTRKQRFNSPSKTVSKHPLQQRPSISPKPQ------------ARTLSTVDHSSEFNHKSNEPTAVPVHNSTSKSGHSSHFSILK-----SSECGPLSKFKDSLQREANSRSSHSSKNKSFP----------------------------------------------------------------------------------------------------------------DTNRSSSKQTSQSSSSPKPRPKLEDSSVPRTGHSQKEPKPRERDRE-VDSRGRAQGVNLVPTGKEQRHRRLAEEQVIRRRWVRSSEEEEGEEDKRT----------------EEGERERKRRRRREPEAEWRAVQPKQRPHTSQHHTQRECNGPNLEEQRRKKRRWSNGDVSSRPYVTDSSPSPPLSPPTPTPVVKPTHPLSSSSSSSFSSSSSSSESDSESSPPRNIAKVPADSTSNKKTVSKSRHEKQ-------------NSGSSSHPERSCLSTPETEKHSRGRHKLYTLVPFGRTEK---------------------------------------------------------------------------------------------------------------------SPTIPHRG-LKKLVVRIDLCLLGR-----------VPSADELTERQSSSSSVSSGKAKEKSSMKHLNHSDQPPGDGRSKRKAENGDLQRENKRNHSCTDKQPSSVHHETEETCVDNQQNGCQDDYFYSKRPVSPLSPP-SNILELSKHSVKAQHAEK------------YYTPPEKDNDSTAQKTQIQKTQPKVEVECIGVSGHLQPLSGS-----RVPPPNLPLH-------------------------------------YRGTVPISDVSHHAEYYMHEAKRLKHRADAMVDKLGKAVNYVDAALSFMECGKAMEEGPLESKSPYTMYAETVELIRYAMRLKSHAGPGASQ-----EDKQLAVLCFRCLALLYWQMFRLKKDHALKYSKVLLDYFKSSPKGPHNPPTRNDSGKGT----------IPPASICSVSIMGSHTGKSPSTVISIPHRIHQMAANHLNITNSVLYSYEYWEVADTLAKE--NKEFFNYLNTLTGPLTLHSSMAHIVQYTRQGLQWIRISANLS-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VQI9-1", "uniprot_id": "AFFL_DROME", "id": "Q9VQI9-1", "name": "AF4/FMR2 family member lilli", "aln": "---------------------------MAQQQQQQMQQQQQHHTSSINNNNSSSIVLLQQQQPQQQQQQLDQLQQYNNNLYSQNYNMEEYERRKRREREKIE----RQQGIQIDDRETSLFGEPRRLTEGDAEITAALGEFFEAREYINNQTVGISRSAPGAGNPRLQPNLAPQAKSLGHSPSSASSAAGPTAASATTSLPGQQQHYQQQQRPPTYVKQADNKPPYNGRGGYPGQPMKNDIPSSSGMAPPRGPPRTSSSNSNSSSVTNNASSGGVPASTPLGPPLSTQMPNGREKSFLGPPAPALHNGTGGRFVPPAASKRPGVGQQPPPPEKDVNKIISDIANIFTVQPLTLIAATPHAPTRENYNLLAPNRQKYAMDIPSSPPSAEPSSLMTPLFAPITSPIAPLVTTPPQASQMPLGGATSGTILAGEALAPLHQLPPTMPKAASGVTSPGPVKPLKTEKNHSLEKQDSCLENDLELSESEDEQRKKEGRSGGNSSNSSESDSSESGSESSSKNDLQHHPNHQQHHHQLQQQQQQQQATMQQQQVLQQQHRSQPLTSNGAQNKKFRHEIIARGSNTITGLLSSSGFGSGGNVGPAGVNSNAVVGTGSGSGGTLSSGGSSSNKTPSPTESNKWNLSRFFHKPANQTNSESVSPGNVSMKVPGILPGGAQIIPESIDVTTAIVKNEKNDMAMEEGEEEDDDEEQQLRYGGGLSVTPVAVKKEAIDAVSEMALGAIPKTQIKRESAETLLSARLSDSGTSASGSSSSSSSSSDSAMGGEVVPMPGPGETLQLPGVPAAITTVMRVQPTQSQKAPPSNSVTLTPILPLPTSPKQRQKKPRKKKAITSAPILDSSDDDEPPPKHPGLDHTAVSVQTQPATDTVKKGRGRPRKQQQSGGSGNLSSASAGSSSQTKGPTLTAAKKPLAKTPLAMSRARKREHSSQSSSNGNTPTKKVATPQLVAAPLKPTSNTAGSSSSDEDSSSSAESSSKSSSSSSSSDDTETQNTNCRIVKLNKTGAVQKKALLGSGSSSPSSSGSEAEDQTTRSQVGSGQALAQQLPPYKQLPISQHSQHLSSSDCSSSSGGCTAVCSSSSGEEDEGRREKERERKPKSDKNKINTLTRIFNPKEGGAKKQGQVVIVDLQEEQQQGKLDAAAQPSAPQAPPAAPAAIMAKPRMTPTQQQQLGAGLASPARTTTPHLTSLICKIDLSKLSRERIMRLKKLTPAQQNGHLTPKDQATNAVHVPNGYAGDTNPAAKVKHEHPVKPEPELDAGYEAKFKPGNVKQEFQLKQERDRDRERERERERERERDREREQPPGRRRKRSSSSSSSPYKEKKRKKEKADQLQMGKELLPVPVLLPSNNHERMPNHDRLSYDKLQLLHEDAAAVIGDVSAPNGSPTKKLLAMSPLPPPPTVTVAPATCNEAVQTTPPSATATSAIAPPVPATRLIYRSYFDRDVEHPSDDPRKNNQFLQEAINRKHAADLERDSFNQVTLYLEAVVYFLLTADAMERCSSE-QATNTMYKDTLSLIKFISTKFRPYQQQSTTNIQHETHNKVAILSLRCQSLISLKLYKLRRKDCRAIINSLTDFFRVGRGDIANGNTPSS--------------ISPSNSVGSQG-----SGSNTPPGRIVPPDIHNMLCKQNEFLSYLNSAHELWDQADRLVRTGNHIDFIRELDHENGPLTLHSTMHEVFRYVQAGLKTLRDAVSHPTHQSQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : . : .: : . *:*. : . *::.: : ...: .: : . . .:. : .. . : . : . : . :. : * . . . . . . :.* .: * : ... * *:. . : : . : : : . . . . . . * : . :: : .. .. :. :: : ... : : .: : . : . * : : * : : : ** . . : .: . .* . . . * .. * .*.: :. :. .: .. : . : . . :. :. . : . : : :. : : : .: .. . .. .. . * : . . . : :: . ::.**** .. .*. *. *.. . . . : . . .. . : : : . *. :*:.: . .. : .* :*** *.* . :: :. .. . .. * . . : .. : : : : . : . : .: .. * : ::. ::. . : . . .:: : . * * .* .: : :::** . ** ** :.:.:. * :*.: *: ..***. . * ::. *** :*:.**:: :: .:::* *. ** :*: ::::*::... : * *:*: . . . *. *: * . :. .... :* **:* .:: .: . : ::: *: ** *.: : :*:. *: **:****:* .:.:* : **: :* :. . ", "identical_positions": 90, "similar_positions": 335, "identity": "5.22%" }, { "cls_id": "homologset.agr.RGD:1308528", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "O35568-1", "uniprot_id": "FBLN3_RAT", "id": "O35568-1", "name": "EGF-containing fibulin-like extracellular matrix protein 1", "aln": "-------------------------------------------------------------MLQTVFLTMLTLALVKSQVTEETITYTQCTDGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLCLPKTAQIIVNNEQPQQETPAAEASSGAATGTIAARSMATSGVIPGGGFIASATAVAGPEVQTGRNNFVIRRNPADPQRIPSNPSHRIQCAAGYEQSEHNVCQDIDECTSGTHNCRLDQVCINLRGSFTCHCLPGYQKRGEQCVDIDECSVPPYCHQGCVNTPGSFYCQCNPGFQLAANNYTCVDINECDASNQCAQQCYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYQVVRSRTCQDINECETTN-ECREDEMCWNYHGGFRCYPQNPCQDPYVLTSENRCVCPVSNTMCRDVPQSIVYKYMNIRSDRSVPSDIFQIQATTIYANTINTFRIKSGNENGEFYLRQTSPVSAMLVLVKSLTGPREHIVGLEMLTVSSIGTFRTSSVLRLTIIVGPFSF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BPB5-1", "uniprot_id": "FBLN3_MOUSE", "id": "Q8BPB5-1", "name": "EGF-containing fibulin-like extracellular matrix protein 1", "aln": "-------------------------------------------------------------MLQTLFLTMLTLALVKSQYTEETITYTQCTDGYEWDPIRQQCKDIDECDIVPDACKGGMKCVNHYGGYLCLPKTAQIIVNNEHPQQETPAAEASSGATTGTVAARSMATSGVVPGGGFMASATAVAGPEVQTGRNNFVIRRNPADPQRIPSNPSHRIQCAAGYEQSEHNVCQDIDECTSGTHNCRTDQVCINLRGSFTCQCLPGYQKRGEQCVDIDECTVPPYCHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQQCYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYEVVRSRTCQDINECETTN-ECREDEMCWNYHGGFRCYPRNPCQDHYVLTSENRCVCPVSNTMCRELPQSIVYKYMSIRSDRSVPSDIFQIQATMIYANTINTFRIKSGNENGEFYLRQTSPVSAMLVLVKSLSGPREYIVDLEMLTVSSIGTFRTSSVLRLTIIVGPFSF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q12805-1", "uniprot_id": "FBLN3_HUMAN", "id": "Q12805-1", "name": "EGF-containing fibulin-like extracellular matrix protein 1", "aln": "-------------------------------------------------------------MLKALFLTMLTLALVKSQDTEETITYTQCTDGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLCLPKTAQIIVNNEQPQQETQPAEGTSGATTGVVAASSMATSGVLPGGGFVASAAAVAGPEMQTGRNNFVIRRNPADPQRIPSNPSHRIQCAAGYEQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQCVDIDECTIPPYCHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQQCYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYQVVRSRTCQDINECETTN-ECREDEMCWNYHGGFRCYPRNPCQDPYILTPENRCVCPVSNAMCRELPQSIVYKYMSIRSDRSVPSDIFQIQATTIYANTINTFRIKSGNENGEFYLRQTSPVSAMLVLVKSLSGPREHIVDLEMLTVSSIGTFRTSSVLRLTIIVGPFSF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32T0U7-1", "uniprot_id": "A0AB32T0U7_DANRE", "id": "A0AB32T0U7-1", "name": "", "aln": "MICSCINSLCNPRAFLQQRETTCSHSRTHTHTHTHTQLHQISSSSTHTAADLQHSSSLTPAEMWTVSLMMAALACVLSQEAEESVSYTRCTEGYEYDPFKEVCTDIDECVLVSDACKAGMKCINHYGGYLCLPQNAQIFINKENE-----------------------------------ASQSSDSVPQTHTETN-----------HRSAANGGS--QCSAGFTRDQHNYCHDVDECSQGLHTCGSDQICYNSRGSYSCQCQPGYQRHGEQCVDRNECLLSHYCMHRCVNTAGSYYCECNDGYQLASNNHSCVDVNECEVSQPCQHQCFNLLGSFICQCEQGYELGPDAVSCVDIDECSFSSYMCQYACVNSEGGYSCTCPDGYQIHRTRMCQDINECETAAHECREDEMCWNYYGGHRCYPRNPCLEPYVRTSENRCSC-QSAAACRGLPQSIVYKYMNMHSERSVPADIFQIQATNIFSSAHYTFRIKDGNDGGQFFLRRFSSAGAMLVLTQSLEGPQELIVDLEMITQHSLMNYRSSSLLRLTIIVGPFPF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: * * :** * ** :**:::**:**:***:**.:: *.***** :*.****.****:**********:.***::*:*: ** :: : *: :* * :* .:* . **:**: :.:** *:*:***: * *.* **:* * ***::*:* ****::****** :** :. ** : ****.**:**:*. *:***:**::***:***:.*: * :**:*:********:*****..* :.* ***** ***:*** ***. * :** **:**:: *:* *********: ***********:**.****:*** : *: *.**** * * : ** :*********.::*:****:******** *::.: *****.**:.*:*:**: *...*****.:** **:* **.***:* *: .:*:**:**********.*", "identical_positions": 261, "similar_positions": 118, "identity": "47.03%" }, { "cls_id": "homologset.agr.RGD:1308529", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R3H9-1", "uniprot_id": "CNS1_MOUSE", "id": "Q8R3H9-1", "name": "Hsp70/Hsp90 co-chaperone CNS1 homolog", "aln": "---MESSEPEPTE---------DASMDAFLEKFQSQPYRGGFREDQWEEEFDKIPLFMKKAPS-EIDPEEFPDLACLQSMIFD-DDRYPEEQAKTYKDEGNDYFKEKDYKKAVLSYSEGLKKKCADPDLNAVLYTNRAAAQYYLGNVRSSLNDVLAAKKLKPGHLKAIIRGALCHLELKHFAEAVNWCDEG-LQIDAKEKKLLEIRAKADKLKRMEERDLRKAKLKEKKEQHQNEALLQAIKARNIRLVS-------ESAGEDED---SASNGPAEILLDGLSSENPYGARLSIDDQGRLSWPVLFLYPEYAQSDFISAFHEDTRFIDHLMAMFS---EAPSWDSEHKYHPENLEVYFEDEDRAELYQVSPDSTLLQVLQHPRCCVKALTPAFLVCVGSSPFCRNYLQGKKVHR-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LB98-1", "uniprot_id": "A0ABK0LB98_RAT", "id": "A0ABK0LB98-1", "name": "", "aln": "-----MTVPWTRS---------WTSSRASLTAAASARTSGRRWAAGASGEFDKIPLFMKKAPS-EIDPKEFPDLACLQSIIFD-DERSPEEQAKTYKDEGNDYFKEKDYKKAVVSYSEGLKKKCADPDLNAILYTNRAAAQYYLGNFRSALNDVLAAKKLKPDHLKAIIRGALCHLELKHFAEAVNWCDEG-LQIDAKEKKLLEMRAKADKLKRMEERDLRKAKLKEKKEQNQNEALLQAIKARNIRLVS-------ESVGEDED---SASNGLAEMLLHGLSSENPCGARLSIDGQGRLSWPVLFLYPEYAQSDFISAFHEDTRFIDHLMAMFS---EAPSWDSEHKYHPDDLEVYFEDEDRAELYQVSPESTLLQVLQHPRCSVKALTPAFLVCVGSSPFCKNFLQGKRVHR-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O95801-1", "uniprot_id": "CNS1_HUMAN", "id": "O95801-1", "name": "Hsp70/Hsp90 co-chaperone CNS1 homolog", "aln": "---MEQPGQDPTS---------DDVMDSFLEKFQSQPYRGGFHEDQWEKEFEKVPLFMSRAPS-EIDPRENPDLACLQSIIFD-EERSPEEQAKTYKDEGNDYFKEKDYKKAVISYTEGLKKKCADPDLNAVLYTNRAAAQYYLGNFRSALNDVTAARKLKPCHLKAIIRGALCHLELKHFAEAVNWCDEG-LQIDAKEKKLLEMRAKADKLKRIEQRDVRKANLKEKKERNQNEALLQAIKARNIRLS--------EAACEDED---SASEGLGELFLDGLSTENPHGARLSLDGQGRLSWPVLFLYPEYAQSDFISAFHEDSRFIDHLMVMFG---ETPSWDLEQKYCPDNLEVYFEDEDRAELYRVPAKSTLLQVLQHQRYFVKALTPAFLVCVGSSPFCKNFLRGRKVYQIR-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1MZY2-1", "uniprot_id": "A0A8M1MZY2_DANRE", "id": "A0A8M1MZY2-1", "name": "", "aln": "---MAAPTQGEDS---------DDGMDEFMEKFKTQKYHNAFNESNWEEEFEKVPMFMKTAPE-NIDPEKHPDLACIQHIIHD-DDRTPEEKARSLKDEGNEYFKEKKYKKAVVSYTEGLKTSCVNPELNAVLYTNRAAAHFHLGNMRSALNDATAAKKLKPDHNKAIIRGAQCLLELRNYAGALQWCDEG-LKLFPTDKKLQELRATADKQKREADRDARKAKVKAKKQQNEKEALLAAIKERGIKLLKTEKPPHRASDSEDEDRDEDTSRALADLQLDGISSQEATGARVYMDEQGVLHWPVMFLYPEHSQTDFISAFSENASFIDHLAVMFGE--ELPPWDIDQKYQPQNLQMFFEDPEKGNLYQVDLQESLLRVLQHQRCSVKAGTPSFIVLVSESPFSRQFLSGKKVQRLKLLK--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z6M6-1", "uniprot_id": "CNS1_DROME", "id": "A1Z6M6-1", "name": "Hsp70/Hsp90 co-chaperone CNS1 homolog", "aln": "MKQMAAQKAWTDEERLELAAQLDAELDAFIDGLEKKRYEEGWPEDRWQEEMDKHPFFMKRAPQ-PGD-DVHPMFEGLQKLKYDPEENTRDELALNYKEDGNFYMKHKKFRMAIYSFTEGIKTKTDNPDVLAVLYNNRSAAHFFIKNYRSSLSDAQRALFYKPDYTKARWRSAQCAYELERFDLCTQMCEEL-LEVDVDNEVAIALLHKNKMKKLEIERNQRKEAAEAKRRLTRFHRLRDAIEQRAIKFDD-------QKVGKKD-------VLSEELLYPKFLPLEDHPVHLDEDG-STLIWPAAFSYPEFLYSDFYQQLPETTTMRDCLATLLT---EKLPYDKAHNYRLGNVHVYYENRKVGCVHKVDEEKQLAEIIAEKGFFVSGGALLFYVVHKDSRVEQEFINERRRPMVYS----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P33313-1", "uniprot_id": "CNS1_YEAST", "id": "P33313-1", "name": "Hsp70/Hsp90 co-chaperone CNS1", "aln": "MSSVNANGGYTKPQK-------YVPGPGDPELPPQLSEFKDKTSDEILKEMNRMPFFMTKLDETDGAGGENVELEALKALAYE---GEPHEIAENFKKQGNELYKAKRFKDARELYSKGLAVECEDKSINESLYANRAACELELKNYRRCIEDCSKALTINPKNVKCYYRTSKAFFQLNKLEEAKSAATFANQRIDPENKSILNMLSVIDRKEQELKAKEEKQQREAQERENKKIMLESAMTLRNITNIK--------------------THSPVELLNEGKIRLEDP-----MDFESQLIYPALIMYPTQDEFDFVGEVSELTTVQELVDLVLEGPQERFKKEGKENFTPKKVLVFMETKAGG-LIKAGKKLTFHDILKKESPDVPLFDNALKIYIVPKVESEGWISKWDKQKALERRSV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *::: *:**. . : :: : .: .* * . *.:** * * :: * :::*: . : .: ** **:*.. : * * .:.* * :* *. * : . :*.. . . . .: :: : . : . . .* : :.. . * *: * * :: : * . * :*. : ** ** . * : . : : :: * : .:: .: :: * . : :. . : :: . * : : . . :: ", "identical_positions": 42, "similar_positions": 96, "identity": "9.98%" }, { "cls_id": "homologset.agr.RGD:1308530", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q2M4I6-1", "uniprot_id": "Q2M4I6_MOUSE", "id": "Q2M4I6-1", "name": "SCAN domain-containing protein 1", "aln": "MAAPQPSQDPQ-SPAA-PPEQQEGAGDCAAPS-------------------------------PDSGSSPAPELPGAPAALNTAPYADAALR----PGASRPGPETFRQRFRQFRYQDAAGPREAFRQLRELSRQWLRPDIRTKEQIVEMLVQEQLQAILPEAARARRLRRRADVRITG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A6K0-1", "uniprot_id": "D4A6K0_RAT", "id": "D4A6K0-1", "name": "SCAN domain-containing protein 1", "aln": "MAAPQPSQAAQ-SPAA-PPEQEEGAGDCAARE-------------------------------PDSMSSPAPELPGAPAALNTAPQADAAPR----PGASRPGPETFRQRFRQFRYQDAAGPREAFRQLRELSRQWLRPDIRTKEQIVEMLVQEQLQAILPEAARARRLRRRPDVRITG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P57086-1", "uniprot_id": "SCND1_HUMAN", "id": "P57086-1", "name": "SCAN domain-containing protein 1", "aln": "MAATEPILAATGSPAAVPPEKLEGAGSSSAPERNCVGSSLPEASPPAPEPSSPNAAVPEAIPTPRAAASAALELPLGPAPVSVAPQAEAEARSTPGPAGSRLGPETFRQRFRQFRYQDAAGPREAFRQLRELSRQWLRPDIRTKEQIVEMLVQEQLLAILPEAARARRIRRRTDVRITG", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***.:* . **** ***: ****..:* . * : :*.* *** .**.:..** *:* * *..** ****************************************************** ***********:***.******", "identical_positions": 106, "similar_positions": 21, "identity": "59.22%" }, { "cls_id": "homologset.agr.RGD:1308531", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U2U2-1", "uniprot_id": "CRKL_RAT", "id": "Q5U2U2-1", "name": "Crk-like protein", "aln": "MSSARFDSSDRSAWYMGPVSRQEAQTRLQGQR-HGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPNRR---FKIGDQEFDHLPALLEFYKIHYLDTTTLIEPAPRYPNPPMGSVSAPNLSTAEENLEYVRTLYDFPGNDAEDLPFKKGELLVIIEKPEEQWWSARNKDGRVGMIPVPYVEKLVRSSPHGKHGNRNSNSYGIPEPAHAYAQPQTTTPLPTVASTPGAAINPLPSTQNGPVFAKAIQKRVPCAYDKTALALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVKIFDPQNPDDNE----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P47941-1", "uniprot_id": "CRKL_MOUSE", "id": "P47941-1", "name": "Crk-like protein", "aln": "MSSARFDSSDRSAWYMGPVTRQEAQTRLQGQR-HGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPNRR---FKIGDQEFDHLPALLEFYKIHYLDTTTLIEPAPRYPSPPVGSVSAPNLPTAEENLEYVRTLYDFPGNDAEDLPFKKGELLVIIEKPEEQWWSARNKDGRVGMIPVPYVEKLVRSSPHGKHGNRNSNSYGIPEPAHAYAQPQTTTPLPTVASTPGAAINPLPSTQNGPVFAKAIQKRVPCAYDKTALALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVKIFDPQNPDDNE----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P46109-1", "uniprot_id": "CRKL_HUMAN", "id": "P46109-1", "name": "Crk-like protein", "aln": "MSSARFDSSDRSAWYMGPVSRQEAQTRLQGQR-HGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPNRR---FKIGDQEFDHLPALLEFYKIHYLDTTTLIEPAPRYPSPPMGSVSAPNLPTAEDNLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKLVRSSPHGKHGNRNSNSYGIPEPAHAYAQPQTTTPLPAVSGSPGAAITPLPSTQNGPVFAKAIQKRVPCAYDKTALALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVKIFDPQNPDENE----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9XYM0-1", "uniprot_id": "CRK_DROME", "id": "Q9XYM0-1", "name": "Adapter molecule Crk", "aln": "--MDTFDVSDRNSWYFGPMSRQDATEVLMNERERGVFLVRDSNSIAGDYVLCVREDTKVSNYIINKVQQQDQIVYRIGDQSFDNLPKLLTFYTLHYLDTTPLKRPACRR-------------------VEKVIGKFDFVGSDQDDLPFQRGEVLTIVRKDEDQWWTARNSSGKIGQIPVPYIQQYD---DYMDEDAIDKNEPSISGSSNVFESTLKRTDLN----------------RKLPAYARVKQSRVPNAYDKTALKLEIGDIIKVTKTNINGQWEGELNGKNGHFPFTHVEFVDDCDLSKNSTEIC", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** ***.:**:**::**:* * .:* :*:******.: .*****.* *:::**:****.: :: ::****.**:** ** **.:******.* .** * :* * :** *.* :****::**:*.*:.* *:***:***..*::* *****::: : ... :.*. .*. .::.: .. . * * :: *.:*:. *.*** ******* **:***:***: *********:**::* ******::.* : ..*. ", "identical_positions": 130, "similar_positions": 86, "identity": "41.8%" }, { "cls_id": "homologset.agr.RGD:1308533", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JZR6-1", "uniprot_id": "A0A0G2JZR6_RAT", "id": "A0A0G2JZR6-1", "name": "", "aln": "MWDNRMDRMTEDALRLNLLKRSLDPADERDDVLAKRLKMEGHEAMERLKMLALLKRKDLANLEVPHELPTKQDGSG---------VKSYEEKLNGNLRPHGDN-RTAGRPGKENIN------------DEPVDMSARRSEPDRGRLTPSPDIIVLSDNEASSPR-----SSSRMEERLKAANLEMFKGKGIEERQQLIKQLRDELRLEEARLVLLKKLRQSQ--LQKENVVQKTPVVQN----------------AASIVQPSPAHVGQQGLSKLPSRPGAQGIEPQNLRTLQGHSVIRSAANTTLPHMLMSQRVIAPNPAQLQGQRGPPKPGIVRTTTPNMNPAISYQPQSSSSVPCQR------------TTSSAIYMNLASHIQPGTVNR---VS-------SPLPSPS-----------AMSDAANSQAAAKLALRKQLEKTLLEIPPPKPPAPLLHFLPSAANSEFIYMVGLEEVVQSVIDSQGKNCASLLRVEPFVCAQCRTDFTPHWKQEKNG----KILCEQCMTSNQKKALKAEHTNRLKNAFVKALQQEQEIEQRLQQQAALSPTT---------------------------------------------------------------------------------------------------------------------APAVSSVSKQETIMRHHTLRQAPQPQSSLQRG-----------IPTSARSMLSNFAQAPQLSVPGGLLGM--------------------------------PGVNIAYLNTG-----------------------------IGGHK------------------------------------------------------------------------APSLADRQREYLLDMIPPRSISQSISGQK-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VHR5-1", "uniprot_id": "P66B_MOUSE", "id": "Q8VHR5-1", "name": "Transcriptional repressor p66-beta", "aln": "-----MDRMTEDALRLNLLKRSLDPADERDDVLAKRLKMEGHEAMERLKMLALLKRKDLANLEVPHELPTKQDGSG---------VKGYEEKLNGNLRPHGDNNRTAGRPGKENIN------------DEPVDMSARRSEPDRGRLTPSPDIIVLSDNEASSPR-----SSSRMEERLKAANLEMFKGKGMEERQQLIKQLRDELRLEEARLVLLKKLRQSQ--LQKENVVQKTPVVQN----------------AASIVQPSPAHVGQQGLSKLPSRPGAQGIEPQNMRTLQGHSVIRSATNTTLPHMLMSQRVIAPNPAQLQGQRGPPKPGIVRTTTPNMNPAISYQPQSSSSVPCQR------------TTSSAIYMNLASHIQPGTVNR---VS-------SPLPSPS-----------AMSDAANSQAAAKLALRKQLEKTLLEIPPPKPPAPLLHFLPSAANSEFIYMVGLEEVVQSVIDSQGKNCASLLRVEPFVCAQCRTDFTPHWKQEKNG----KILCEQCMTSNQKKALKAEHTNRLKNAFVKALQQEQEIEQRLQQQAALSPTT---------------------------------------------------------------------------------------------------------------------APAVSSVSKQETIMRHHTLRQAPQPQSSLQRG-----------IPTSARSMLSNFAQAPQLSVPGGLLGM--------------------------------PGVNIAYLNTG-----------------------------IGGHK------------------------------------------------------------------------APSLADRQREYLLDMIPPRSISQSISGQK-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WXI9-1", "uniprot_id": "P66B_HUMAN", "id": "Q8WXI9-1", "name": "Transcriptional repressor p66-beta", "aln": "-----MDRMTEDALRLNLLKRSLDPADERDDVLAKRLKMEGHEAMERLKMLALLKRKDLANLEVPHELPTKQDGSG---------VKGYEEKLNGNLRPHGDN-RTAGRPGKENIN------------DEPVDMSARRSEPERGRLTPSPDIIVLSDNEASSPR-----SSSRMEERLKAANLEMFKGKGIEERQQLIKQLRDELRLEEARLVLLKKLRQSQ--LQKENVVQKTPVVQN----------------AASIVQPSPAHVGQQGLSKLPSRPGAQGVEPQNLRTLQGHSVIRSATNTTLPHMLMSQRVIAPNPAQLQGQRGPPKPGLVRTTTPNMNPAINYQPQSSSSVPCQR------------TTSSAIYMNLASHIQPGTVNR---VS-------SPLPSPS-----------AMTDAANSQAAAKLALRKQLEKTLLEIPPPKPPAPLLHFLPSAANSEFIYMVGLEEVVQSVIDSQGKSCASLLRVEPFVCAQCRTDFTPHWKQEKNG----KILCEQCMTSNQKKALKAEHTNRLKNAFVKALQQEQEIEQRLQQQAALSPTT---------------------------------------------------------------------------------------------------------------------APAVSSVSKQETIMRHHTLRQAPQPQSSLQRG-----------IPTSARSMLSNFAQAPQLSVPGGLLGM--------------------------------PGVNIAYLNTG-----------------------------IGGHK------------------------------------------------------------------------GPSLADRQREYLLDMIPPRSISQSISGQK-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N9R4-1", "uniprot_id": "A0A8M1N9R4_DANRE", "id": "A0A8M1N9R4-1", "name": "", "aln": "-----MERMSEEALRLNLLKRGLEAPDEREE--AKRLKMDGHEAMERLKMLALLKRKDLAALEGAAVAAAMAEGKGPCGSQGLMGAVAYEEKMNGSLRVGGHG--GPSKNGKENIV------------DEPVDMSARRSEMVRERRTPSPDVIILSDNEASSPR-----STPHPEEKQHQANLEMFKGKTGEERQQMIKALREELRLEEAKLVLLKKLRQSQ--MQKENVVQKVPVVQN----------------APSSVQPSPMHS-SQGLGKLPVRPGMHSSEPQNLRTAQGHTVIRSAANASLPPMMMSQRVIAPNPAQLQGQRLPSKPGMGRSSTGGLGNAVSYQQAASQQVGVSQRS----------GSSSAIYMNLAHMQAAGAAGVGVGVSGVGAVSPSTLSSASSV--------ASLNDQASSQAAAKLALRKQLEKTLLEIPPPKPPAPLLHFLPSAANSEFIYMVGLEEVVQSVIDSQGKMRGSLPHVEPFFCAQCRTDFTPHWKQEKSG----RILCEQCMTSNQKKALKAEHTNRLKNAFVKALQQEQEIEQRLQQQAALSPSS---------------------------------------------------------------------------------------------------------------------GQTVPSVSKGETMIRHHALRQTPQPQAALQRG-----------LSSSARGVLSNFAQASQLSVASGLLGMTSKRCGSSSSSG-GGTSSSRPQHDSRRQIYNIPGLNIAYLNPGA----------------------------IGGHK------------------------------------------------------------------------ASSLADRQREYLLDMIPPRSISQSITGQK-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9PF79-1", "uniprot_id": "M9PF79_DROME", "id": "M9PF79-1", "name": "", "aln": "-----MAKMEVDDVVDLSLGSGRDPALTITPAPPPAALSNRDLRALTANNAGLTITPSASPATNNGTTSNSSNTNSNSSSTTTTTNNNNNSSSNTNSSSANNNNNNNSINASDGVTGATSGSIGGGQDENKVQRRVLRPRTEPKSYAEAPDIVLLPARTNGRQQNGNIDSETDDEEMPPYVPIKELSHAELKEREKSLRKLRQDLRNEETKLMLLKKLKQSQQVMKENLVVTPTSVSPNNPLSAIPAALTSKGSLSVTPTSAVPLPAHSKGSRSSLSGSGGPAVSISATNSRTGSSSSAAAAASAIAAAAMSGQHRSGSNSILPPPRSSLPAGATLAAGTTITPATSSSHRSSNLPPRTNLPNLTITPSVTITPTSAPPSSLKPRNVPGTISNSVSITPALPLSQSHQNQHNDQKNDRSTPREDAQTPAQRQAAAKMALRKQLEKTLLQIPPPKPPPPEMHFIPNPSNTDFVYLLGLETVVDYLTVN----KKANAVAAPFRCAQCKIDFTPVWKWEKQTNKDPKVICEQCVTSNVKKALKAEHTNRLKQAFVKALQQEQEIEQRLASQSSPSPVDNHGSSGGGNSLSVSAVSSNSSSSHMQREREQLQASHASAAAALVNLPPSVTVIPTKCQTPTPATPRPTPPPPQSQATPPPSSGGSRSSRAAATAAAAAIAAQQAGILSPGPSPAHHHEPTTSSRSSRNDRLDHHHQSQQQQQRDQRERDQQQRDQQSQQQAQNYDKYSAATLAAAAHLSALGGMGGLNINSLASLGNLGNLGNLSQLGNLAALGGLGNFGGASTGSANPAAGLSGSSPAATAAAMQAFQQQLFRALGQGLGGNPQHMMQFAPLLYSYQMAMAQAAQVAGEMTMALTGKFITGYQECDSVTFNNNNKKSSSSSGSAKNSSSSNSMAEVQRAAELQRQYLLEMIPPQQQSGASGSRQNNWKA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :* : : * . :.. . : . : .* . : . : .. :.. * . ... . ..:.: :: *: . *.. : :**:::*. . . : * . ** . :: :. :**:: :: **::** **::*:*****:*** :::: ** ..* * : : ... * .:* . .* . . . .: * : :*: :::. ** : : . : * * . .* :: : * . . :*. . .:** .* .*: . :: * . . *. *****:***********:*******.* :**:*..:*::*:*::*** **: : . : . ** ****: **** ** **. :::****:*** *************:**************** .*:: ** :..* *. : : ** * * : :*. . : :.:* *.:**. .*: *: * . . *.. :**: *: **:***:****:. * : .:: ", "identical_positions": 168, "similar_positions": 178, "identity": "17.76%" }, { "cls_id": "homologset.agr.RGD:1308534", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZWD2-1", "uniprot_id": "D3ZWD2_RAT", "id": "D3ZWD2-1", "name": "", "aln": "MAHEGHFQHSGMVWALRLILAWVFLVTCGGSHPLQARSWGHPGLAANVSTGQLQLAGHPQSSVPPSYPRIQVPSSQTPATPEPCCTA----DIDRPEASNPESLLASCGAPSPECEFFLGHLQRALRGR------FHPLLFGVRRMQPLCMELCQIWFTTCQADFICGPTWLQSSGKRGCEPSCRTYGQTFANATDLCHSALGHALRVAAP----------GSSHCFNIS-------------------ISS-----PGAR---------RRPRAWISNVAGSGSGSGSGDSPE------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8QZY4-1", "uniprot_id": "RTBDN_MOUSE", "id": "Q8QZY4-1", "name": "Retbindin", "aln": "MAHEGHSQHSGLVWALRPILAWIFLVACGWSHPLQTRSWGHPGLAAKVRTGQLQPAGHPQSSVLPSYPRIQVPGSQTPPVPVPCCTA----EIDRP-----ESLLESCGAPSPECEFFLGQLQGALRDR------FHPQLFGARPVQPLCPELCQIWFTTCQADFICGPTWLQSSGERGCEPSCRTYGQTFANATDLCHSVLGHVLRVAAP----------GSSHCLNVS-------------------ISS-----PGAR---------RRPRAWISNVVGSGSGSGSGDSPEPMFGFQYVSLP-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BSG5-1", "uniprot_id": "RTBDN_HUMAN", "id": "Q9BSG5-1", "name": "Retbindin", "aln": "MDCRVHMRPIGLTWVLQLTLAWILLEACGGSRPLQARSQQHHGLAADLGKGKLHLAG-------------------------PCCPS----EMDTTETSGPGNHPERCGVPSPECESFLEHLQRALRSR------FRLRLLGVRQAQPLCEELCQAWFANCEDDITCGPTWLPLSEKRGCEPSCLTYGQTFADGTDLCRSALGHALPVAAP----------GARHCFNIS-------------------ISAVPRPRPGRRGREAPSRRSRSPRTSILDAAGSGSGSGSGSGP-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IY94-1", "uniprot_id": "A0A0R4IY94_DANRE", "id": "A0A0R4IY94-1", "name": "", "aln": "MKMGVSRVLLGLAHLTSLFAAVVMSHEGACLR--DGRHKATPSPERHLQECSLYTEN-------------------------SCCSETDIQDLSVSVSTVENTHWDKCGVLSPLCESFLKRVVCFYRCSPDAARWPHPHQGSSLKAVPLCHSFCRDWFEACKMDMTCARDWTTDPRGQNCTGACVPYQQMYQHGRDLCESLWGDAFMTVEDDPGEEDGVEGSSCGCLTLSPSDREVIAALRVQEGDPEELDTTKSGLPQYRAPCPPAQPQTRSATAPPQARRSSVSNGLRKRSVLATDMEGSGSGF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *:. * :: . : : * . .: .* . .**. ::. . . **. ** ** ** :: * : . *** .:*: ** *: *: *. * . :.* :* .* * : .. ***.* *..: .. .: *:.:* :.: * * . : :. *. ..* . . ", "identical_positions": 41, "similar_positions": 61, "identity": "13.4%" }, { "cls_id": "homologset.agr.RGD:1308535", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "B5DFG8-1", "uniprot_id": "B5DFG8_RAT", "id": "B5DFG8-1", "name": "", "aln": "MAASAPPPPDKLEGGSG-------PAPPP----APPSTGRKQGKAGLQMKSPEKKRRKSNTQGPAYSHLTEFAP-------PPTPMV---DHLVASNPFEDDFGAPKMGGAGPPFLGSPVPFGG-----------------FRVQGGMAGQVPP-------------GYGTGGGGGPQPLRRQPPPFP-----------------------------------PNPMGPAFN---------------------------------------------------------------------------MPPQGPGYPPPGNMNFPSQ------------------PFNQSLGQNFSPPGGQMIPGPVGGFGP---------MISPTMGQ---------------------------------------PPRGELGPPPLPQRFTQPGAPFGPS-LQRPGQ----------GLPSLPPNTSPFP------------GPDPGFP-----------GPGGEDGGKPLN-------------------------------------------PPAPTAFPQEPHS--------------GSPAAAVNG----------------------------------------------------NQPSFPPSSSGRGGGTPDANSLAPPGK---AGGGSGPQPPPG------------------------------------------------LVYPCGACRSEVNDDQDAILCEASCQKWFHRECTGMTESAYGLLTTEASAVWACDLCLKTKEIQSVYIREGMGQLVAANDG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BRQ0-1", "uniprot_id": "PYGO2_HUMAN", "id": "Q9BRQ0-1", "name": "Pygopus homolog 2", "aln": "MAASAPPPPDKLEGGGG-------PAPPP----APPSTGRKQGKAGLQMKSPEKKRRKSNTQGPAYSHLTEFAP-------PPTPMV---DHLVASNPFEDDFGAPKVGVAAPPFLGSPVPFGG-----------------FRVQGGMAGQVPP-------------GYSTGGGGGPQPLRRQPPPFP-----------------------------------PNPMGPAFN---------------------------------------------------------------------------MPPQGPGYPPPGNMNFPSQ------------------PFNQPLGQNFSPPSGQMMPGPVGGFGP---------MISPTMGQ---------------------------------------PPRAELGPPSLSQRFAQPGAPFGPSPLQRPGQ----------GLPSLPPNTSPFP------------GPDPGFP-----------GPGGEDGGKPLN-------------------------------------------PPASTAFPQEPHS--------------GSPAAAVNG----------------------------------------------------NQPSFPPNSSGRGGGTPDANSLAPPGK---AGGGSGPQPPPG------------------------------------------------LVYPCGACRSEVNDDQDAILCEASCQKWFHRECTGMTESAYGLLTTEASAVWACDLCLKTKEIQSVYIREGMGQLVAANDG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V9W8-1", "uniprot_id": "PYGO_DROME", "id": "Q9V9W8-1", "name": "Protein pygopus", "aln": "MTHNLGMAPYRLPGPAGGLCPPDFKPPPPTDIISAPSNPKKRRKTSSAANSAAAVAAAAAAAAAANSMQQQQAPPTPQDLLPPPPMGGFGDTIIASNPFDDSPQVSAMSSSAAAAMAAMNQMGGGPGGGHFGGGGPGGHPHWEDRMGMGGGPPPPPHMHPHMHPHHPGGPMGHPHGPHPHMGGPPPMRGMSPMHPHQMGPGPGVGLPPHMNHGRPGGPGGPGGPVPMGSPMGGIAGMGGMSPMGGMGGPSISPHHMGMGGLSPMGGGPNGPNPRAMQGSPMGGPGQNSPMNSLPMGSPMGNPIGSPLGPPSGPGPGNPGNTGGPQQQQQQPPQPPMNNGQMGPPPLHSPLGNGPTGHGSHMPGGPIPGPGPGPGGLVGPGGISPAHGNNPGGSGNNMLGGNPGGGNSNNNGSNTSNASNNNQNPHLSPAAGRLGVPTSMQSNGPSVSSVASSSVPSPATPTLTPTSTATSMSTSVPTSSPAPPAMSPHHSLNSAGPSPGMPNSGPSPLQSPAGPNGPNNNNSNNNNGPMMGQMIPNAVPMQHQQHMGGGPPGHGPGPMPGMGMNQMLPPQQPSHLGPPHPNMMNHPHHPHHHPGGPPPHMMGGPGMHGGPAGMPPHMGGGPNPHMMGGPHGNAGPHMGHGHMGGVPGPGPGPGGMNGPPHPHMSPHHGHPHHHHNPMGGPGPNMFGGGGGGPMGPGGPMGNMGPMGGGPMGGPMGVGPKPMTMGGGKMYPPGQPMVFNPQNPNAPPIYPCGMCHKEVNDNDEAVFCESGCNFFFHRTCVGLTEAAFQMLNKEVFAEWCCDKCVSSKHIPMVKFKC-----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: . .* :* * .* .*** :.**. :*: *:. :*. : : ..* * : ** **.** * ::*****:*. .. :. :... :.: :** :. : **.* ** * * **:* ***: * ***..:. **.*** *** . *.* *::..**:. : ..:* **: * ** ***: *: *. ..** *. * . :....* : *. .:.: *.:** * **.**:* **.* :..:. * ** .:. **. *.*. :.* * *..* *. :* . *.:. ** .***.** * * :**** *:.****:::*::**:.*: :*** *.*:**:*: :*..*. * *.** *:.:*.* * :: ", "identical_positions": 143, "similar_positions": 134, "identity": "17.31%" }, { "cls_id": "homologset.agr.RGD:1308536", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M8U6-1", "uniprot_id": "A0ABK0M8U6_RAT", "id": "A0ABK0M8U6-1", "name": "Cochlin", "aln": "MPSSWSPALCLGAWLLLLLLPRLARAEGAGELVPIPITCFTRGLDIRKEKADVLCPGGCSLEEFSVFGNIVYASVSSICGAAVHRGVIGTSGGPVRVYSLPGRENYSSVAANGIQSQTLSRWSASFAVTKGKSSTQEATGRAVSTANPPSG------KRLKKTPEKKTGNKDCKADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGVGTEGPHVGLVQASEHPKIEFYLKNFTSAKDVLFAIKEVGFRGGNSNTGKALKHTAQKFFTADTGVRKGIPKVVVVFIDGWPSDDIEEAGIVAREFGVNVFIVSVAKPIPEELGMVQDVAFVDKAVCRNNGFFSYHMPNWFGTTKYVKPLVQKLCTHEQMMCSKTCYNSVNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIGAKIAAVQFTYDQRTEFSFTDYNTKENVLAVLANIRYMSGGTATGDAISFTVRNVFGPIRDSPNKNFLVIVTDGQSYDDVRGPAAAAHDAGITIFSVGVAWAPLDDLKDMASKPKESHAFFTREFTGLEPIVSDVIRGICRDFLESQQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62507-1", "uniprot_id": "COCH_MOUSE", "id": "Q62507-1", "name": "Cochlin", "aln": "MPSSRIPALCLGAWLLLLLLPRFARAEGA---VPIPVTCFTRGLDIRKEKADVLCPGGCSLEEFSVFGNIVYASVSSICGAAVHRGVIGTSGGPVRVYSLPGRENYSSVDANGIQSQMLSRWSASFAVTKGKSSTQEATGRAVSTAHPPSG------KRLKKTPEKKTGNKDCKADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPHVGLVQASEHPKIEFYLKNFTSAKDVLFAIKEVGFRGGNSNTGKALKHTAQKFFTADTGVRKGIPKVVVVFIDGWPSDDIEEAGIVAREFGVNVFIVSVAKPIPEELGMVQDVAFVDKAVCRNNGFFSYHMPNWFGTTKYVKPLVQKLCTHEQMMCSKTCYNSVNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIGAKIAAVQFTYDQRTEFSFTDYNTKENVLAVLANIRYMSGGTATGDAIAFTVRNVFGPIRDSPNKNFLVIVTDGQSYDDVRGPAAAAHDAGITIFSVGVAWAPLDDLRDMASKPKESHAFFTREFTGLEPIVSDVIRGICRDFLESQQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43405-1", "uniprot_id": "COCH_HUMAN", "id": "O43405-1", "name": "Cochlin", "aln": "MSAAWIPALGLGVCLLLLPGP--AGSEGA---APIAITCFTRGLDIRKEKADVLCPGGCPLEEFSVYGNIVYASVSSICGAAVHRGVISNSGGPVRVYSLPGRENYSSVDANGIQSQMLSRWSASFTVTKGKSSTQEATGQAVSTAHPPTG------KRLKKTPEKKTGNKDCKADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPHVGLVQASEHPKIEFYLKNFTSAKDVLFAIKEVGFRGGNSNTGKALKHTAQKFFTVDAGVRKGIPKVVVVFIDGWPSDDIEEAGIVAREFGVNVFIVSVAKPIPEELGMVQDVTFVDKAVCRNNGFFSYHMPNWFGTTKYVKPLVQKLCTHEQMMCSKTCYNSVNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIGAKIAAVQFTYDQRTEFSFTDYSTKENVLAVIRNIRYMSGGTATGDAISFTVRNVFGPIRESPNKNFLVIVTDGQSYDDVQGPAAAAHDAGITIFSVGVAWAPLDDLKDMASKPKESHAFFTREFTGLEPIVSDVIRGICRDFLESQQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8AW56-1", "uniprot_id": "Q8AW56_DANRE", "id": "Q8AW56-1", "name": "Cochlin", "aln": "-MSLWFAVLHVLGILSLSWCT--SGSELN---VATPISCGTRAVDLSDTHLLVLCPANCSLWSLSVFGSGVYASISSICGAAIHRGIIGLSGGPVEVHGLQGRTNYLSSYAHGVQSQSLSQWSASFTVARTISLPLEVSSQTSSSAIVASGAAKKPVKKIVKKPPPATAHKDCPVDMALLLDSSYNIGQRRFNLQKNFVSKLATMLKVGTQGPHVGVVQTSETPRTEFYLTNYTTAKDVTFAIKEIPYIGGNTNTGKAILHTVRNFFSPDFGVRRGYPRVIVVFVDGWPSDNVEEAAILARESGINIFFVSVAKPSPEEASLVSDQDFMRKAVCKDNEFFTFTMPSWFSTNKFVKPLAQKLCSIDQMLCSKTCYNSVDLGFLIDGSSSVGDGNFRLVLDLLVSIARSFDISDIGSRIGAIQFTYDQRMEFNFNDHVLKDNALRALQKIPYMSGGTATGDAINFAVRSLFKP-RSSSNRKFLIIITDGQSYDDVRVPAMAAQREGITVYAVGVAWAPMEDLKAMASEPKESHVFFTREFTGLGQFQQPIVRGICRDFTEFN-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ..* : * * . : :* .. .::* **.:*: . : ****..*.* .:**:*. ****:*******:***:*. *****.*:.* ** ** * *:*:*** **:*****:*:: * . *.:.:: *:* .:* *:: *.* *.:*** .*:*:*:*.*:**************.*:* ** :**:*****:**:** *: ****.*:*:**** *****: : ***:*****: **.::**: * ***:* *:*:***:******::***.*:*** *:*:*:****** *** .:*.* *: ****::* **:: **.**.*.*:****.****: :**:*********::.***********.****:*::: .**::*:*****::*.*:******* **.*.*: *:*.* .: :* ************ *:**.:* * *.*.*::**:*:*********: ** **: ***:::*******::**: ***:*****.********* : . ::******* * : ", "identical_positions": 315, "similar_positions": 150, "identity": "56.15%" }, { "cls_id": "homologset.agr.RGD:1308538", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A8W0-1", "uniprot_id": "A0A8I6A8W0_RAT", "id": "A0A8I6A8W0-1", "name": "Rab11 family-interacting protein 2", "aln": "MMLSEQAQKWFPTHVQVTVLQAKDLKPKGKSGTNDTYTIIQLGKEKYSTSVAEKTLEPV-WKEEASFELPGLLMQGNPEKYILFLIVMHRSLVGLDKFLGQVAINLNDIFEDKQRRKTEWFRLESKQGKRIKNRGEIKVNIQFMRNNMTASMFDLSMKDKTRSPFAKLKDKMKG-------RKSDGVFSDTSSAIVPSTHMPDANPEFSSGEMQMKSKPKKPFLLGPQRLSSAHSMSDLTG----------------------------SHLSSEK--------LKSSTVGPTHLLSHQINSFGVVPESGSLKSPHRRTLSFDTSKLNQPGSIVDEGE---HCFGRQSDPFTNVTASLPQKFATLPRKKNP----------------------------FEESSEPWDSSTNLFSKPIEVRKESKREKR---EKVSLFERVTGKRDSRRSDKLNNGGSDSPCDLKSP-------------------------------------------SAFNENRQDYFEYESTN------------PFTAKFRASTIMPSSSFHMNPTSSDDLRKIPDSNPFDATAGYRSLTYEEVLQELVKHKELLRRKD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------THIRELEDYIDNLLVRVMEETPSILRVPYEPSRKAGMDGKPYTRVFLQEVRSWQNPSRSQEQARNSEAHSPDSGMLIIHEDNLTTS--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "G3XA57-1", "uniprot_id": "RFIP2_MOUSE", "id": "G3XA57-1", "name": "Rab11 family-interacting protein 2", "aln": "MMLSEQAQKWFPTHVQVTVLQAKDLKPKGKSGTNDTYTIIQLGKEKYSTSVAEKTLEPV-WKEEASFELPGLLMQGSPEKYILFLIVMHRSLVGLDKFLGQVAINLNDIFEDKQRRKTEWFRLESKQGKRIKNRGEIKVNIQFMRNNMTASMFDLSMKDKTRSPFAKLKDKMKG-------RKSDGVFSDTSSAIVPSTHMPDANPEFSSGEMQMKSKPKKPFLLGPQRLSSAHSMSDLTG----------------------------SHLSSEK--------LKSSTVGPTHLLSRQIDSFGVVPESGSLKSPHRRTLSFDTSKLNQPGSIVDEGE---HSFGRQSDPFTNVTASLPQKFATLPRKKNP----------------------------FEESSEPWDSSMNLFSKPIEVRKESKREKR---EKVSLFERVTGKRDSRRPDKLNNGGSDSPCDLKSP-------------------------------------------SAFSENRQDYFEYESTN------------PFTAKFRASTIMPSSSFHVNPTSSEDLRKIPDNNPFDATAGYRSLTYEEVLQELVKHKELLRRKD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------THIRELEDYIDNLLVRVMEETPSILRVPYEPSRKAGK---------------------------------------------FTNS--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7L804-1", "uniprot_id": "RFIP2_HUMAN", "id": "Q7L804-1", "name": "Rab11 family-interacting protein 2", "aln": "MMLSEQAQKWFPTHVQVTVLQAKDLKPKGKSGTNDTYTIIQLGKEKYSTSVAEKTLEPV-WKEEASFELPGLLIQGSPEKYILFLIVMHRSLVGLDKFLGQVAINLNDIFEDKQRRKTEWFRLESKQGKRIKNRGEIKVNIQFMRNNMTASMFDLSMKDKTRSPFAKLKDKMKG-------RKNDGTFSDTSSAIIPSTHMPDANSEFSSGEIQMKSKPKKPFLLGPQRLSSAHSMSDLSG----------------------------SHMSSEK--------LKAGTIGQTHLLGHQLDSFGTVPESGSLKSPHRRTLSFDTSKMNQPDSIVDEGE---LCFGRQNDPFTNVTASLPQKFATLPRKKNP----------------------------FEESSETWDSSMNLFSKPIEIRKENKREKR---EKVSLFERVTGKKDSRRSDKLNNGGSDSPCDLKSP-------------------------------------------NAFSENRQDYFDYESTN------------PFTAKFRASNIMPSSSFHMSPTSNEDLRKIPDSNPFDATAGYRSLTYEEVLQELVKHKELLRRKD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------THIRELEDYIDNLLVRVMEETPSILRVPYEPSRKAGK---------------------------------------------FSNS--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VWS3-1", "uniprot_id": "Q9VWS3_DROME", "id": "Q9VWS3-1", "name": "", "aln": "--------MWSPTHCSVTVQRARGLLTKGKNGTNNCFVTIALGKEKYQTSVKDKAETSVNWNEECELKIP-----DQGNRAELTLTCLHRNNLGIDEFLGQATLPLNEMDVYD-RPRAKWFKLESKPGKEKKNKERGELEVRIAFVVKSGSLTDLSKKDKHKSSIGQLASSVGGSLLSIGNGEKRRGIKKLAGSLSSKLHIRSKKKNQEAGADDSSSFGGSFASLGTPNSSNGRGQNGGSGRRRGGQRAGEADPGVISEDEDEFVFDNLSHKSSGSSLNIQRIGLQPPPVGTPNFTPRHPSPLLNNGVSGVGSGSAKGKQAVLPATLDEDASIDAEMEQLELDFSVRAHARANANASASGNASTLPPPSKPPRIPLSQVDEQPAAGSLEREKPKEKPAEVESDKDEWASKLYGGGKYLEIGSSNSLKRRSWEDRVPLPASVEEPPPLHSSSSSSSSSSDSDDDDEKPPQAAPPPVPVPASLPVPSAAASTASADPVVATSSSLFSPDVEHRNFDTFNASFAKYEQRNSTAIFADEPELEDLTVELEKPAPTPTARPKPQPRATADLRAEEEKAKEEAARQLRAEEDARLEAELRLNEERLREEEEAMQRELEEEKERQKQLQMDEQQRREAKRWEEDQRLLSFAKRSTSLEEPVPEKQELKHERELVAKQEPEKTLDTAEPEPEHNFLTPEQSPKEFQTNGSGSGSGERWEKRLGKFKYGNKRDKYNNDNDSNSPSPKSTERIIIGHEKSGSHADRRSEISAQLAKKYEGKSREELMLIANGMENEALLQRQRVKELEDYLDNLLLRVMETHPKILQNPYSRTTSAKRYG---------------------------------------TWSFWSSSRTRATPTH", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *** .*** :*:.* .***.***: :. * ******.*** :*: .* *:**..:::* .. :: * * :**. :*:*:****.:: **:: . * :::**:**** **. **: . :::::: :.*: *** *** :*.:.:* ..: * :. :.. :.:: .. *: . : : .:* : .* . **. . *..:. .. :* ** ** . *:. .:* .:: :: ..: ** ... : . :. .:.::: ** * * *. : .. :*..** . : :*** .:* .*...: * *. .* :*: .... ::* ::*.* * : ... ....*** * :.* *. . .: .**. * :*.::. . *:: : .* :. *** :. :*: *: .: ** ::* **.:: :::*****:****:**** *.**: **. : .* :.* ", "identical_positions": 142, "similar_positions": 195, "identity": "16.05%" }, { "cls_id": "homologset.agr.RGD:1308539", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "O60282-1", "uniprot_id": "KIF5C_HUMAN", "id": "O60282-1", "name": "Kinesin heavy chain isoform 5C", "aln": "MADPAECSIKVMCRFRPLNEAEILRGDKFIPKFKGDETVVIGQGKPYVFDRVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKTHVPYRDSKMTRILQDSLGGNCRTTIVICCSPSVFNEAETKSTLMFGQRAKTIKNTVSVNLELTAEEWKKKYEKEKEKNKTLKNVIQHLEMELNRWRNGEAVPEDEQISAKDQKNLEPCDNTPIIDNIAPVVAGISTEEKEKYDEEISSLYRQLDDKDDEINQQSQLAEKLKQQMLDQDELLASTRRDYEKIQEELTRLQIENEAAKDEVKEVLQALEELAVNYDQKSQEVEDKTRANEQLTDELAQKTTTLTTTQRELSQLQELSNHQKKRATEILNLLLKDLGEIGGIIGTNDVKTLADVNGVIEEEFTMARLYISKMKSEVKSLVNRSKQLESAQMDSNRKMNASERELAACQLLISQHEAKIKSLTDYMQNMEQKRRQLEESQDSLSEELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEMKKALEQQMESHREAHQKQLSRLRDEIEEKQKIIDEIRDLNQKLQLEQEKLSSDYNKLKIEDQEREMKLEKLLLLNDKREQAREDLKGLEETVSRELQTLHNLRKLFVQDLTTRVKKSVELDNDDGGGSAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALESALKEAKENAMRDRKRYQQEVDRIKEAVRAKNMARRAHSAQIAKPIRPGHYPASSPTAVHAIRGGGGSSSNSTHYQK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P56536-1", "uniprot_id": "KIF5C_RAT", "id": "P56536-1", "name": "Kinesin heavy chain isoform 5C", "aln": "MADPAECSIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVIGQGKPYVFDRVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKTHVPYRDSKMTRILQDSLGGNCRTTIVICCSPSVFNEAETKSTLMFGQRAKTIKNTVSVNLELTAEEWKKKYEKEKEKNKALKSVIQHLEVELNRWRNGEAVPEDEQISAKDQKNLEPCDNTPIIDNITPVVDGISAE-KEKYDEEITSLYRQLDDKDDEINQQSQLAEKLKQQMLDQDELLASTRRDYEKIQEELTRLQIENEAAKDEVKEVLQALEELAVNYDQKSQEVEDKTRANEQLTDELAQKTTTLTTTQRELSQLQELSNHQKKRATEILNLLLKDLGEIGGIIGTNDVKTLADVNGVIEEEFTMARLYISKMKSEVKSLVNRSKQLESAQTDSNRKMNASERELAACQLLISQHEAKIKSLTDYMQNMEQKRRQLEESQDSLSEELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEVKKALEQQMESHREAHQKQLSRLRDEIEEKQRIIDEIRDLNQKLQLEQERLSSDYNKLKIEDQEREVKLEKLLLLNDKREQAREDLKGLEETVSRELQTLHNLRKLFVQDLTTRVKKSVELDSDDGGGSAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALESALKEAKENAMRDRKRYQQEVDRIKEAVRAKNMARRAHSAQIAKPIRPGHYPASSPTAVHAVRGGGGSS-NSTHYQK", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***********************************:******************************************************************************************************************************************************************************************************************************************************************************************************************************:**.******:*************************************:*** ***:* ********:********************************************************************************************************************************************************************************************** *************************************************************************************:******************************:*****************:****************:*******************************************************.************************************************************************************************************************:******* *******", "identical_positions": 940, "similar_positions": 13, "identity": "98.22%" }, { "cls_id": "homologset.agr.RGD:1308540", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AXX4-1", "uniprot_id": "SAS10_RAT", "id": "Q6AXX4-1", "name": "Something about silencing protein 10", "aln": "MVKRSRRRGAAQWATVRAKAGRTATDENEDDLGSPPSPGDSSYYQDQVDEFHEARSRAVLAKGWNEVESGEEDD--DEEEEVLPLNIDDENDEDGESS--EEEEDGE------------DDDGGSSVQSEAEASVDPSLSWGQRKRLYYDTDYGSKSRGRQSQQEVEEEEREEEEEAQVIQRRLTQALQEDDFGVAWVEAFAKPVPQVDEA--ETRVVKDLAKVSVKEKLKMLRKESPELLELIEDLKVKLTEVKDELEP-LIQLVEKGVIPPGKGSQYLKTKYNLYLNYCANISFYLILKAR----------------------------------------------------------------------------------------------RVPAHGHPVIERLVTYRNLIN----KLSVVDQKLSSEIRHLLTAKEGA----------GKKDLNPKAKLTKTKPKSAKQTDVN----ADLTEEPEFDE--------AALEFYKEMEDRPELKRKKEENSAEEQALEE-------------------QNAKRAITYQIAKNRGLTPRRKKIDRNPRVKHREKFRRAKIRRRGQVREVRREEQR--YSGELSGIRAGVKKSIKLK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JI13-1", "uniprot_id": "SAS10_MOUSE", "id": "Q9JI13-1", "name": "Something about silencing protein 10", "aln": "MVKKSRRRGAAQWAAVRAQAGLTATDENEDDLGLPPSPGDSSYYQDQVDEFHEARSRAVLAKGWNEVESGEEDG--DEEEEVLPLDIDDGDDEDGESS--EEEEVGE------------DDDGGSSVQSEAEASVDPSLSWGQRKKLYYDTDYGSKSRGRQSQQEVEEEEREEEEEAQIIQRRLAQALQEDDFGVAWVEAFAKPVPQVDEA--ETRVVKDLAKVSVKEKLKMLKKESPELLELIEDLQAKLTEVKDELEP-LLQLVEKGVIPTGRGSEYLKTKYNLYLNYCANISFYLILKAR----------------------------------------------------------------------------------------------RVPAHGHPVIERLVTYRNLIN----KLSVVDQKLSSEIRHLLTAKDGA----------VKKEMTPKAKLTKTKPKSVKQAAA-----VALTDEPDFDG--------AALKYYKEMEDRQELKRKKEENSAEEQALEE-------------------QNAKRAITYQIAKNRGLTPRRKKIDRNPRVKHREKFRKAKIRRRGQVREVRREEQR--YSGELSGIRAGVKKSIKLK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NQZ2-1", "uniprot_id": "SAS10_HUMAN", "id": "Q9NQZ2-1", "name": "Something about silencing protein 10", "aln": "MVGRSRRRGAAKWAAVRAKAGPTLTDENGDDLGLPPSPGDTSYYQDQVDDFHEARSRAALAKGWNEVQSGDEEDGEEEEEEVLALDMDDEDDEDGGNAGEEEEEENA------------DDDGGSSVQSEAEASVDPSLSWGQRKKLYYDTDYGSKSRGRQSQQEAEEEEREEEEEAQIIQRRLAQALQEDDFGVAWVEAFAKPVPQVDEA--ETRVVKDLAKVSVKEKLKMLRKESPELLELIEDLKVKLTEVKDELEP-LLELVEQGIIPPGKGSQYLRTKYNLYLNYCSNISFYLILKAR----------------------------------------------------------------------------------------------RVPAHGHPVIERLVTYRNLIN----KLSVVDQKLSSEIRHLLTLKDDA----------VKKELIPKAKSTKPKPKSVSKTSAAACAVTDLSDDSDFDEK-------AKLKYYKEIEDRQKLKRKKEENSTEEQALED-------------------QNAKRAITYQIAKNRGLTPRRKKIDRNPRVKHREKFRRAKIRRRGQVREVRKEEQR--YSGELSGIRAGVKKSIKLK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9I7W5-1", "uniprot_id": "SAS10_DROME", "id": "Q9I7W5-1", "name": "Something about silencing protein 10", "aln": "------------------------MDSDGDDYVMSGS--DQEYDDEEREILEDLRKQRKKPH--------------DPVQEVLGFSDDDDDDDDDDEE-EQQDVAEL------------MRDSDIEGAEDDDRDLPNTMDWGSKRSTYYNTDFVDQDYSSYNAQEEEQ-ARAEEEEAKKIQLRLAKRMSEADFQLDNVEAAPAGSSDDNELSHITKVTSDLAGLSERERRQLMHSESPEFIILTQDFQQHLDEVKNLLKP-VLNYVRKHDVPMVPALQYAGLCHTVLTTYCSNVAFYLLLKAR----------------------------------------------------------------------------------------------RIDVKAHPVIRRLVQLKDLIE----ELKPRYEEYIRPQLEALLERIED----------GDAFTVLDVAQRKAKLQILNKYNDG----QQASVSSDDDD---------------NDDDDDAESKEKDLQEEAGEEEEE-------------------EDARRGITYQMAKNKGLTPHRKKELRNPRVKHRGKYRKALIRRKGAVRTVRKELQR--YGGELSGIKAGVTKSVKFRT", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12136-1", "uniprot_id": "SAS10_YEAST", "id": "Q12136-1", "name": "Something about silencing protein 10", "aln": "--------------MVRKGSNRTKTSEVGDEINPYGLNEVDDFASKREKVLLGQSTFGDSNKDDDHSLLED-----EDEEEVLAMDEDDESIDEREDEEEEEEEELDGAAAYKKIFGRNLETDQLPEEDEENGMLDNENAWGSTKGEYYGADDLDDDEAAKEIEKEALRQQKKHLEELNMNDYLDEEE-EEEWVKSAKEFDMGEFKNSTKQADTKTSITDILNMDDEARDNYLRTMFPEFAPLSKEFTELAPKFDELKKSEENEFNKLKLIALGSYLGTISCYYSILLHELHNNEDFTSMKGHPVMEKILTTKEIWRQASELPSSFDVNEGDGSESEETANIEAFNEKKLNELQNSEDSDAEDGGKQKQEIDEEERESDEEEEEEDVDIDDFEEYVAQSRLHSKPKTSSMPEADDFIESEIADVDAQDKKARRRTLRFYTSKIDQQENKKTDRFKGDDDIPYKERLFERQQRLLDEARKRGMHDNNGADLDDKDYGSEDEAVSRSINTQGENDYYQQVQRGKQDKKISRKEAHKNAVIAAREGKLAELAENVSGDGKRAINYQILKNKGLTPKRNKDNRNSRVKKRKKYQKAQKKLKS-VRAVYSGGQSGVYEGEKTGIKKGLTRSVKFKN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. *: .: ... . : . : : :*** :. ** . :: . ::: . .: : : **. : **.:* ... . . :: : :. * :: * : * :: * : : . .*: :. . : : ::. **: * ::: :..: :. : . :. :.: * : :*.: : :.:* : ::*: .:. :: . : . . : : : .: : : * : : .: *: :. : .. :.:*.*.**: **:****:*:* **.***:* *:::* : :. ** * * * ** :**: *:.:*:*:: ", "identical_positions": 57, "similar_positions": 140, "identity": "9.03%" }, { "cls_id": "homologset.agr.RGD:1308541", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L4N7-1", "uniprot_id": "A0ABK0L4N7_RAT", "id": "A0ABK0L4N7-1", "name": "", "aln": "MACCHKVMLLVDTAG--------DAARHSSARRAALRLLTYLSCRFGLARVHWTFKFFDSQGARNR--PSRVSDFRELGSRSWEDFEEELEARLGDRPPGAHLPG-----PTPRATHTHGALMETLLDYQWDRPEITSPTKPILRSSGRRLLDADSEAKEAETALGGFGNAVFLLAPCPHSQRELLQFVSGCEAQAQRVPLTPKQLMEKVLPKRVQEVMIARNITLYWVDTTERSKLWASPDHTGYWTVCELLHHGGGTILPAETWNLGFTKARETVLPCGGELSPGPHLSPWISALPIDATVNCLLYNS-EYEASFPRVEGTLFLPVKG-KEIQETWAICLEPLAMHQRHFQKPVRIFLKGSVTQWSLPMSSALGTDNWMLQSPEEHKSTQRLLFQELVSRLTAEEFHLVASVDPGDGWPPITGIISPFSANAMILTVLRAKEAEFQRHFLQTAVTEGSQDVTSLFSDAVDSVLNQVHNSFEDPAS----SVSRVPEWVQQELS-RTSPWSPALVEKWFPFSNVCGATSDLMESFLLLHAASPDNN---ESSRTESELTRCLSELYQRRSHEESTVVNQERSRKKRGIPRTPVRQKMNTMSRSLKMLNVARLNVKAQKLHPDGSPDMAVEKGLPKTVIGRTADKLEDRGRVLRSSKLKEFKTEEELLAYIHDNYQKTVATGEITLHSCAQNTVSTIKIFLKSKDVKELEMTCMNHMNSNLLKTSKTLRQNLGGKTDKEDKVRECQLQVFLRLEMCQQCPSVLDRTEEVEHVVEEVTDLLRVVCLTKDSAYLSEFLEEILG-LYIDSIPGTIGQLYHSLGLKIPQKLAGVLPTDFFSDDSMTQES----MSPPPSSSTHRSVSAITESEQLEELRTRSAKKRRKNALIRHKSIAEISQALRQIEVPKVSKRATRSASNPRTWSTEESAHPASVQLPLPRKDTVQEVTKVRRNLFNQGMLSPSKRGLKKGLPRSRSVSTLECLQHKQDKLKKTKSSTFQGY-KLLTKSVAETPVHKQISRRLLHRQIKGRSSDPGPDIHVVEESPEKEDEMILRRSPRIKQLSFSRTNSGSFYSVSQPKSRSVQRIHSSQQ--KSDQRENFPVQSIRSPKTLLFGALSETPSSSKKGSPGIKRSSRSMLDSEISTAYETPKK-NNQKSPSFSKTTPRSFPRTAQTLLYTPER----LQNSSTEITSAEGTISEVAIKTPSSHGYNSPSASKVTPQKRASPAKEETSP-LTELPSIPRESDVQPPQCSS-----NSVSSSSEGPCCPASPPPLAGQARGQCLTPVRYSFRTPPR-TALAVTSTYQEHQELPLRRASQAREPPQRLEEKALKIPKKP---TDTSTSPLSPKEHFTSPGCNVSPHQP-SISSLSASPSGELSWKENQTSPSVTTSVSCPVPSTPPRTPQRMICP-IPPSPPSKLRRPCRKKSCLPQDFPECQPGPCAVPVLGTTTSPGTVRGSREEQ-------SQPSEGHSYLGTSFGSDWHVSSPMLIASDTECLPLIDEAQLHRLENQEVKSGVLPGEEGEEPE-TTTAEPPSVSDLGILVPAPSSVSNSPELLSYTLCRVADGRQSHDAAQQESPPASEATD----SPQTYDVELEMQASGLPKLRIKKID---PGVLLEPEALGR-ETLLGEEGTFPALSMPKASKSSGRSEHTYLSPPCLLPSHSTPGKSGG--QTFICQSCTPSRCPPSTPSPFQADVGVSWTPSPKQSGKTTPEIIKDWPRRKRAVDCSAGPSAGRGEASMDLPGSLSLLEPEPEGKEQSLEQDLCKVLILEDFELEGVCQLPDQSPPKHSVSMAEETS-WEQFGLG-RKRLLSAKEESEYNGKRLCDSPSEDPQASEHKECSPCWSAPPVPSVGDDEVFVSGSTPPSGYMVRSCLSASGLQALTQSPLLFQGRTPSSHSKDTRDEDVDVFPSTAEESPFSQTLSRKRPF-RTYTRKKLIS------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BQ33-1", "uniprot_id": "TICRR_MOUSE", "id": "Q8BQ33-1", "name": "Treslin", "aln": "MACCHKVMLLVDTAG--------VSAPHSPARRAALRLLTYLSCRFGLARVHWTFKFFDSQGARSR--PSRVSDFRELGSRSWEDFEEELEARLGDRPPGAHLPG-----PTPRATHTHGALMETLLDYQWDRPEITSPTKPILRSSGRRLLDADGEAREAQAALGGFGNAVFLLAPCPHSQRELLQFVSGCEAQAQRVPLTPKQVMEKVLPKRVQEVMIARNITLYWVDTTERSKLWASPDHVGYWTVCELLHHGGGTILPAETWSLGFTKARETVLPCGGELSHKPHPSPWISALPIDATVNCLLYNS-EYEASFPRIEGTLFLPVQG-KEIEETWAISLEPLAMHQRHFQKPVRIVLRGSVAQWSLPVSSALGTDSWMLQSPEEHRSTQRLLFQELVSRLTAEEFHLVASVDPGEGWPPITGIISPFSANAMILTVFRAKEAEFQSHFLQTAATEGSQDTASLFSDVVDSVLNQSHNLFEDPAS----SAPCVPEWVQQELS-HTSSWSPALVEKWFPFSNASGATSDLMESFWLLHAASPDND---ESSKTESELTRCLSELYQR-SHEESTVVNQERSRKKRGIPRTPVRQKMNTMSRSLKMLNVARLNVKAQKLHPDGSPDTAVEKGLQKAVIGRTADKLEDRGRILRSSKLKEFKTEEELLAYIHDNYQKAVATEEITLYSCAQNMVSTIKMFLKSKDIKELEVACLSHVNSNLLKTSKTLRQNLAGKMDTEDKVGECQLQVFLRLEMCEQCPSVLDRPDEVERIVEEVTDLLRLVCLTKDSAYLSEFLEEILR-LYIGSIPGTIGQLYHSLGLKIPQKLAGVLPTGFFSDDSMSQES----MSPPPSSSTHRSVSAITESEQLEELRTRSAKKRRKNALIRHKSIAEISQTLRQIEVPKVSKRATR----------NENSHSASIQLPVPRKDTIQEVTKVRRNLFNQEMLSPSKRGLKKGLPRSHSVSALECLHHKQDKFKKTKSSTFQGYCKLLTKSVAETPVHKQISRRLLHRQIKGRSSDPGPDIHVVEESPEKEDEMTLRRSPRIKQLSFSRTNSGSFYSVSQPKSRSVQRIHSSQQ--ESEQRENFPVQSIQSPKTLLFGALSEIPSSSKKGSAQIKRSLRSMLDSEISTSYETPKK-SNQKSPSFSKTTPRRFPRTAQTLLYTPER----LQNSPTEMTSAEGTISEATIKTPSSHGYNSPFASKVTSQKTVSPAKEETSPPLTKLPSTPRESDVQPPQCSSDCTWPHSVNSSPEGPYYPASPPPMAGQARSQCLTPIRYSFRTPPR-TALAGTSKQQEHQELPLPRASQTQEPPQGLEKKALKIPKKP---AHTSTSPLSPEEHYS--GCDVSPHQP-RNSLSASPPPGELNWKEHQTSPSVTSSVSCPVPSTPPRTPQRMTCP-IPPSPPSKLRRSCRKKSCPPQDFPECHPGPSAAPVLSSATSPGAVTGSREEQ-------SQFSEGQSYLGTGFRSDCHVSSPVLTASDTKCLPLIDEAQLHGLKNQEVKSGILPGEEGEEPESTIADELPSVSDPGILVPAPSSVSSSSELLPYPLCCTADGKQRQDAAQQGSPRASEATS----SPQTYEVELEMQASGLPKLRIKKID---PGVLLEAEALGK-EAPLGEEGALPALCMPKASKSSGRTEHPYLSPPCLRPSHSTPGKNGG--QTFICQSCTPSRCPPSTPSPFQADAGVSWTPSPKQSGKTTPEIIKDWPRRKRAVDCSAGPSAGRGEASMDLPGSLSLLEPEPEGKERSLEQDLSKVLISEEFELEGVCQLPDQSPPKDSASVTEETS-WGQFGLG-RKRFLSAKEESEYKVKRVCDSLSEDPQASKQKECSPRWSALPLHSVGDDEVFVSGSTPPSGCMVRSCLSASGLQALTQSPLLFQGRTPSSHSTDTRDEEVDVFPSTAEESPFSHTLSRKRPF-RTYTRKKLIS------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z2Z1-1", "uniprot_id": "TICRR_HUMAN", "id": "Q7Z2Z1-1", "name": "Treslin", "aln": "MACCHKVMLLLDTAG--------GAARHSRVRRAALRLLTYLSCRFGLARVHWAFKFFDSQGARSR--PSRVSDFRELGSRSWEDFEEELEARLEDR---AHLPG-----PAPRATHTHGALMETLLDYQWDRPEITSPTKPILRSSGRRLLDVESEAKEAEAALGGLVNAVFLLAPCPHSQRELLQFVSGCEAQAQRLPPTPKQVMEKLLPKRVREVMVARKITFYWVDTTEWSKLWESPDHLGYWTVCELLHHGGGTVLPSESFSWDFAQAGEMLLRSGIKLSSEPHLSPWISMLPTDATLNRLLYNSPEYEASFPRMEGMLFLPVEAGKEIQETWTVTLEPLAMHQRHFQKPVRIFLKGSVAQWSLPTSSTLGTDSWMLGSPEESTATQRLLFQQLVSRLTAEELHLVADVDPGEGRPPITGVISPLSASAMILTVCRTKEAEFQRHVLQTAVADSPRDTASLFSDVVDSILNQTHDSLADTAS----AASPVPEWAQQELG-HTTPWSPAVVEKWFPFCNISGASSDLMESFGLLQAASANKE---ESSKTEGELIHCLAELYQRKSREESTIAHQEDSKKKRGVPRTPVRQKMNTMCRSLKMLNVARLNVKAQKLHPDGSPDVAGEKGIQKIPSGRTVDKLEDRGRTLRSSKPKDFKTEEELLSYIRENYQKTVATGEIMLYACARNMISTVKMFLKSKGTKELEVNCLNQVKSSLLKTSKSLRQNLGKKLDKEDKVRECQLQVFLRLEMCLQCPSINESTDDMEQVVEEVTDLLRMVCLTEDSAYLAEFLEEILR-LYIDSIPKTLGNLYNSLGFVIPQKLAGVLPTDFFSDDSMTQENKSPLLSVPFLSSARRSVSGSPESDELQELRTRSAKKRRKNALIRHKSIAEVSQNLRQIEIPKVSKRATK----------KENSHPAPQQPSQPVKDTVQEVTKVRRNLFNQELLSPSKRSLKRGLPRSHSVSAVDGLEDKLDNFKKNK-----GYHKLLTKSVAETPVHKQISKRLLHRQIKGRSSDPGPDIGVVEESPEKGDEISLRRSPRIKQLSFSRTHSASFYSVSQPKSRSVQRVHSFQQD-KSDQRENSPVQSIRSPKSLLFGAMSEMISPSEKGSARMKKRSRNTLDSEVPAAYQTPKK-SHQKSLSFSKTTPRRISHTPQTPLYTPER----LQKSPAKMTPTKQAAFKESLKDSSSPGHDSPLDSKITPQKRHTQAGEGTSL-ETKTPRTPKRQGTQPPGFLPNCTWPHSVNSSPESPSCPAPPTSSTAQPRRECLTPIRDPLRTPPRAAAFMGTPQNQTHQQPHVLRAARAEEPAQKLKDKAIKTPKRPGNSTVTSSPPVTPKKLFTSPLCDVSKKSPFRKSKIECPSPGELDQKEPQMSPSVAASLSCPVPSTPPELSQRATLDTVPPPPPSKVGKRCRKTSDPRRSIVECQPDASATPGVGTADSPAAPTDSRDDQKGLSLSPQSPPERRGYPGPGLRSDWHASSPLLITSDTEHVTLLSEAEHHGIG--DLKSNVLSVEEGEGLR-TADAEKSSLSHPGIPPSPPSCGPGSPLMPSRDVHCTTDGRQCQASAQLDNLPASAWHSTDSASPQTYEVELEMQASGLPKLRIKKID---PSSSLEAEPLSKEESSLGEESFLPALSMPRASRSLSKPEPTYVSPPCPRLSHSTPGKSRG--QTYICQACTPTHGPSSTPSPFQTDG-VPWTPSPKHSGKTTPDIIKDWPRRKRAVGCGAGSSSGRGEVGADLPGSLSLLESE--GKDHGLELSIHRTPILEDFELEGVCQLPDQSPPRNSMPKAEEASSWGQFGLSSRKRVLLAKEEADRGAKRICD-LREDSEVSKSKEGSPSWSAWQLPSTGDEEVFVSGSTPPPSCAVRSCLSASALQALTQSPLLFQGKTPSSQSKDPRDEDVDVLPSTVEDSPFSRAFSRRRPISRTYTRKKLMGTWLEDL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DRL4-1", "uniprot_id": "TICRR_DANRE", "id": "Q6DRL4-1", "name": "Treslin", "aln": "-MASQNVVFAIDVDYRPEGTQNTTNAYQDHLKQWILRVLLSLGHRYGLEKVRWGYKFFNSRTVKSATLITRGSDFKELQEKVFSDFEEELHVKFTTEGKSPRSQEKSHKLKPSPACCVQNALKEILLDFQWDRPDLTSPTKVTLRPR-RSSRSGRNIPLQDCDMLSVDKNVLFVVSECPRSKAELEDYLSMRREDSR----HHKDINEQMLPKGLIDMLMQRNVVLHWADSGVFKADHVAKDYTGIETLMERLGLVGGQVVPMLSPCLPLMDQHPKMN---------SLLALGVDAFPIDSTNSYLHLSKRMQQQLFPPLGASFSWIADG---TKRSCNVTLEPVSYRQRSLRAPVDVLLKGVLQSLDILSLSHSAIETWILQCPDAELGQEAFQHLKQLS---TGGHAMLAEVSEGD--VVCSAVLSVLSSCTAQITVLQPLLAQEGQLLPADLVSLDTTDISGDLPDVVSSVLSVMYDIMEEDDCSDHEKMPLVPDWANQELKQQSSSRSNGMVEGWFPLSDQSGISCHLMESMRLLHAAPEEKEKGEEYSDTQQEITSSLSEFYQSSTAGSSGSLRS----KKRGTQCTPVRQKMKTMSRSLQMLNFARLNVKAQKTQGD-SGSAGSGKGTEKGGKKSSGDRTKPG--------LLHFSSEEELLSHLGLTYQKAVENRTMSVPSQVQDLLSVVKSFLKSN----TEASLLNLVQKHVLKSCQSIRQHYGNSSDDESKIRECQLQAVLRLELCKQTE--QEDEEVVEQRVEDVADMLRNISRSKDAVYLSRFMQEEVLPLYMNSIPKVLADVYHSLGTQLPEALVAVLPSDFFSDESLAKDS----VSVSLSSFSATQSNISSVGDHLEELRNRSAKKRRQSMITRHKSMTEAPQALRQIEMPRKSTRLAKP-------KLCVPIEKTAVEQPPLPKQPVQEVTKVRRNLFNQVTVSPSK---KSKMPRSQSVSAVEGIKKRKRSDVDND-----DRHTLLTKKVSETPLHKQVSSRLLHRQRTGRKSGE-SDVCIIEESPIKP-AADLRRSPRIKSLTRR--HSSVFYSSSQPRSRNLDRVVSSSQLSHSEGKGKFSVSSVRSPVRLLFGATQSPGRLRHTTVSSLEDQASKGLPLRCSSFENQNKTPQKLRSDALASAVGCRTPQSPRTPNRTVGDNGMALRGSPFQSPAAKSIVVETPMKSPLKGILKTPIKKSLLDCVSPNGAWLRSPGCKTPKKCVTWSPSPRKP-------VPENQVNVPDSPVFAKRHSPRLVTPGKNSSPEEKIVFKTPDKVPQRKSKTSPEIILRRLEIPVNIDPETCKSITRSGKIRTLSLPYKTSKGSDEFLPQSESGSFPFCNSPLKPNIQKTIQSPIP---------THRMCTRSGNTPVKESCSPSSNSQGITGTSPSPRKSLSSAVAKSSPSP----SFGPSRSGVGNQNNSSISNVEKHTDDDK---IIVQNKANDEKAEEASSSDSQQFDCSEFSITTDDESIDISEAAVVKTQLVGGIKMNIAFSRKPSKSDVFEFEGKQTTSTGTPLTRSYGFRQTPDRRQREAEARLGYSSGKPKISTPRTRRTPACGKQSSPQPLTYEVEMEMQASGLPKLKLRRTDSFNAGDLPSSATKGMTSHLVHRNKTNLKAPQIDSPLVQSSRHPGCISPSLCSRATPAKGTPGKGVQTYICQSITPTHHPTSS----QSPLASPLTPSPQSRGWPTPENLNSWPRKKRARIETCG---NKEQVIKGVP-------------------LLEKTGVIEDPELEGIFRIQGVEELKESLSTPISQR---------KLGLRSSQVMDHQGSPEGMDWTETMAQMCDAKDST------------KTEQFAWMGRKVDTPKVKKQVSASGIFALTQSPLLYKKSAVIKEATQFSGS-----KSELEISPLCQPRRRRTPS-RTYSRKKLLD------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..::*:: :*. * :. :: **:* *. *:** :*:* :***:*: .:. :* ***:** .: :.******..:: . .: .. * .:.** * ***:*****::***** **. * . . . : *. *.:*::: **:*: ** :::* . ::: *:: *::*** : :::: *::.::*.*: . : *: * *: * * ** ::* : : . : . : :. :* *:* . * .. : ** : . : ... :.: : ***:: :** :: ** :.*:* : . .: * . :.*:* .*: . : : . : :* : ::*.*. *: :.::* :*: : :** :. *: . .: .. * :. :.*.*.*:*. :: : : . . **:*.:*** :::. * .:** ***:.: .* :..****: **:**. ::: * * *: *: .*:*:** : .* .. **** *******:**.***:***.********* : * * . . ** * : *: : .*.:*****::: .***:* . : : : .:: :*.:* ****: * :. ::. :**:.:::**: . . * *.*: *****..****:* * : : :*: **:*:*:** :. ::*:.**:.*::* : **:.*** .:.::*:*** :*: *..***:.****:*::::. :* . * : . . . .:.*:***.*******:. : ****::* .* *****:*: *.* :: . :. : . *:.:************* :**** * :***:***::: :..: . ... . .****.*:***:***:* ****** .**.*. .*: ::**** * ********.*: :*. *** ***:**.::*: * .* .*: : : .*.*::** ***** .. .. . :: . * . .: : *. .: :* :::.:. .::.:* * *: *. : ..:: : .:* . . .:* ..: . * :. * . . : * .. . .:.* . .. . :. . : ::** : . .. : . . *. : : .. . : ..: . *:. * .* . .. . : * . ** .: . .: .*.* ..: *.* . *. ... ..: . . : ::: .. : :. ... *: . .* . ::* : : : . * : :* .: .: . : * . . . . : . :. . .* **:**:**********:::: * .. .. . . . : .: :. . . :**. : .: *. **:***: **:: *.*: *: . ****: * .**: ::.***:*** .* .: :. .:* : :. : *: ****: :: . . :.* . . . : . :: . . * .: .. *: : . * *. . *:. :***.: ********:: : ..:.: .. * * **:.:. *: * ***:****:. ", "identical_positions": 458, "similar_positions": 617, "identity": "23.24%" }, { "cls_id": "homologset.agr.RGD:1308542", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JZ79-1", "uniprot_id": "SIR1_RAT", "id": "A0A0G2JZ79-1", "name": "NAD-dependent protein deacetylase sirtuin-1", "aln": "-MADEAALALQAGGSPSAA-AAMEAASQPADEPLRKRPRRDGPGLGRSPGEPSAAAAAAAAAAGCEAASAAAPAALWREAAGAAAASA-EREAPATAAAGDGDNGPGLR---REPRAADDFDDDEGEEEDE-AAAAAAAAIGYRDNLLLADEIITNGFHSCESDDDDRASHASSSDWTPRPRIGPYTFVQQHLMIGTDPRTILKDLLPETIP--------PPELDDMTLWQIVINILSEPPKRKKRKDINTIEDAVKLLQECKKIIVLTGAGVSVSCGIPDFRSRDGIYARLAVDFPDLPDPQAMFDIEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQR--IIQCHGSFATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEP------------------------------LAIMKPEIVFFGENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLGDCDVIINELCHRLGG---EYAKLCCNPVKLSEITEKPPRTQK----------------ELVHLSELPPTPLHISEDS----------------------SSPERTVPQDSSVIATLVDQTIKNKVDDLEVSEPKSCVEEKSQEVQTYRNVESIN--------VENPDFKAVGSSTGDKNERTSVAETVRKCWPNRLAKEQISKRLD-GNQYLFVPPNRYIFHGAEVYSD----SEDDALSSSSCGSNSDSG-------------------TCQSPSLEEPLEDESEIEEFYNGLEDDADRPECAGGS--GADGGDQEAVNEAIAMKQELTDVNCTPDKSEHY--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q923E4-1", "uniprot_id": "SIR1_MOUSE", "id": "Q923E4-1", "name": "NAD-dependent protein deacetylase sirtuin-1", "aln": "-MADEVALALQAAGSPSAA-AAMEAASQPADEPLRKRPRRDGPGLGRSPGEP--SAAVAPAAAGCEAASAAAPAALWREAAG-AAASA-EREAPATAVAGDGDNGSGLR---REPRAADDFDDDEGEEEDEAAAAAAAAAIGYRDNLLLTDGLLTNGFHSCESDDDDRTSHASSSDWTPRPRIGPYTFVQQHLMIGTDPRTILKDLLPETIP--------PPELDDMTLWQIVINILSEPPKRKKRKDINTIEDAVKLLQECKKIIVLTGAGVSVSCGIPDFRSRDGIYARLAVDFPDLPDPQAMFDIEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQR--ILQCHGSFATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEP------------------------------LAIMKPEIVFFGENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLGDCDVIINELCHRLGG---EYAKLCCNPVKLSEITEKPPRPQK----------------ELVHLSELPPTPLHISEDS----------------------SSPERTVPQDSSVIATLVDQATNNNVNDLEVSES-SCVEEKPQEVQTSRNVENIN--------VENPDFKAVGSSTADKNERTSVAETVRKCWPNRLAKEQISKRLE-GNQYLFVPPNRYIFHGAEVYSD----SEDDVLSSSSCGSNSDSG-------------------TCQSPSLEEPLEDESEIEEFYNGLEDDTERPECAGGSGFGADGGDQEVVNEAIATRQELTDVNYPSDKS-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96EB6-1", "uniprot_id": "SIR1_HUMAN", "id": "Q96EB6-1", "name": "NAD-dependent protein deacetylase sirtuin-1", "aln": "-MADEAALALQPGGSPSAAGADREAASSPAGEPLRKRPRRDGPGLERSPGEPGGAAPEREVPAAARGCPGAAAAALWREAEAEAAAAGGEQEAQATAAAGEGDNGPGLQGPSREPPLADNLYDEDDDDEGEEEEEAAAAAIGYRDNLLFGDEIITNGFHSCESDEEDRASHASSSDWTPRPRIGPYTFVQQHLMIGTDPRTILKDLLPETIP--------PPELDDMTLWQIVINILSEPPKRKKRKDINTIEDAVKLLQECKKIIVLTGAGVSVSCGIPDFRSRDGIYARLAVDFPDLPDPQAMFDIEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQR--IIQCHGSFATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEP------------------------------LAIMKPEIVFFGENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLGDCDVIINELCHRLGG---EYAKLCCNPVKLSEITEKPPRTQK----------------ELAYLSELPPTPLHVSEDS----------------------SSPERTSPPDSSVIVTLLDQAAKSN-DDLDVSESKGCMEEKPQEVQTSRNVESIAE------QMENPDLKNVGSSTGEKNERTSVAGTVRKCWPNRVAKEQISRRLD-GNQYLFLPPNRYIFHGAEVYSD----SEDDVLSSSSCGSNSDSG-------------------TCQSPSLEEPMEDESEIEEFYNGLEDEPDVPERAGGAGFGTDGDDQEAINEAISVKQEVTDMNYPSNKS-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VK34-1", "uniprot_id": "SIRT1_DROME", "id": "Q9VK34-1", "name": "NAD-dependent histone deacetylase sirtuin-1", "aln": "MMENYEEIRLGHIRSKDLG-------NQVPDTTQFYPPTKFDFG----------AEILASTSTEAEAEAEATATTTEPATSELAGKANGEIKTKTLAAREEQEIGANLEHKTKNPTKSMGEDEDDEEEEEEDDEEEEE-----------DDEEGITGTSNEDEDSSSNCSSSVEPDWKLR-------WLQREFYTGRVPRQVIASIMPHFATG------LAGDTDDSVLWDYLAHLLNEPKRRNKLASVNTFDDVISLVKKSQKIIVLTGAGVSVSCGIPDFRSTNGIYARLAHDFPDLPDPQAMFDINYFKRDPRPFYKFAREIYPGEFQPSPCHRFIKMLETKGKLLRNYTQNIDTLERVAGIQR--VIECHGSFSTASCTKCRFKCNADALRADIFAQRIPVCPQCQPNKEQSVDAS-----------VAVTEEELRQLVENGIMKPDIVFFGEGLPDEYHTVMATDKDVCDLLIVIGSSLKVRPVAHIPSSIPATVPQILINREQLHHLKFDVELLGDSDVIINQICHRLSDNDDCWRQLCCDESVLTESKELMPPEHSNHHLHHHLLHHRHCSSESERQSQLDTDTQSIKSNSSADYILGSAGTCSDSGFESSTFSCGKRSTAAEAAAIERIKTDILVELNETTALSCDRLGLEGPQTTVESYRHLSIDSSKDSGIEQCDNEATPSYVRPSNLVQETKTVAPSLTPIPQQRGKRQTAAERLQPGTFYSHTNNYSYVFPGAQVFWDNDYSDDDDEEEERSHNRHSDLFGNVGHNYKDDDEDACDLNAVPLSPLLPPSLEAHIVTDIVNGSNEPLPNSSPGQKRTACIIEQQPTPAIETEIPPLKKRRPSEENKQQTQIERSEESPPPGQLAAV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P06700-1", "uniprot_id": "SIR2_YEAST", "id": "P06700-1", "name": "NAD-dependent histone deacetylase SIR2", "aln": "----MTIPHMKYAVSKTSENKVSNTVSPTQDKDAIRKQPDDIINNDEPSHKKIKVAQPDSLRETNTTDPLGHTKAALGEVASMELKPTNDMDPLAVSAASVVSMSNDVLKPETPKGPIIISKNPSNGIFYGPSFTKRESLNARMFLKYYGAHKFLDTYLPEDLNSLYIYYLIKLLGFEVKDQALIGTINSIVHINSQERVQDLGSAISVTN----VEDPLAKKQTVRLIKDLQRAINKVLCTRLRLSNFFTIDHFIQKLHTARKILVLTGAGVSTSLGIPDFRSSEGFYSKIKHLG--LDDPQDVFNYNIFMHDPSVFYNIANMVLPPEKIYSPLHSFIKMLQMKGKLLRNYTQNIDNLESYAGISTDKLVQCHGSFATATCVTCHWNLPGERIFNKIRNLELPLCPYCYKKRREYFPEGYNNKVGVAASQGSMSERPPYILNSYGVLKPDITFFGEALPNKFHKSIREDILECDLLICIGTSLKVAPVSEIVNMVPSHVPQVLINRDPVKHAEFDLSLLGYCDDIAAMVAQ-----------KCGWTIPHKKWNDLKNKNFK--------------------CQEKDKGVYVVTSDE------------------------HPKTL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P53685-1", "uniprot_id": "HST1_YEAST", "id": "P53685-1", "name": "NAD-dependent protein deacetylase HST1", "aln": "----MNILLMQRIVS--------FILVVSQGR---------YFHVGELTMTMLKRPQEE---ESDNN-------------ATKKLKTR-------------------------LTYPCILGKDKVTGKFIFPAITKDDVMNARLFLKDNDLKTFLEYFLPVEVNSIYIYFMIKLLGFDVKDKELFMALNSNITSNKERSSAELSSIHAKAEDEDELTDPLEKKHAVKLIKDLQKAINKVLSTRLRLPNFNTIDHFTATLRNAKKILVLTGAGVSTSLGIPDFRSSEGFYSKIRHLG--LEDPQDVFNLDIFLQDPSVFYNIAHMVLPPENMYSPLHSFIKMLQDKGKLLRNYTQNIDNLESYAGIDPDKLVQCHGSFATASCVTCHWQIPGEKIFENIRNLELPLCPYCYQKRKQYFPMSNGNNT----VQTNINFNSP-ILKSYGVLKPDMTFFGEALPSRFHKTIRKDILECDLLICIGTSLKVAPVSEIVNMVPSHVPQILINRDMVTHAEFDLNLLGFCDDVASLVAK-----------KCHWDIPHKKWQDLKKIDYN--------------------CTEIDKGTYKIKKQP------------------------RKKQQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * . . : : :. .: : . : . . . : : : . * : .. *::. :: .:**:********.* ******* :*:*::: * *** :*: : * :** *:::*. : * : * * ** : : :************.** ***. :::*****:**:* *::: : : .* :* ** * .. .::**::.**** **..:* : * **** **:**** **: * . :* ***:****: : * .**:.*** .* : :.: * .: : . : :..: : ", "identical_positions": 108, "similar_positions": 100, "identity": "12.31%" }, { "cls_id": "homologset.agr.RGD:1308543", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q00577-1", "uniprot_id": "PURA_HUMAN", "id": "Q00577-1", "name": "Transcriptional activator protein Pur-alpha", "aln": "MADRDSGSEQGGAALGSGGSLGHPGSGSGSGGGGGGGGGGGGSGGGGGGAPGGLQHETQELASKRVDIQNKRFYLDVKQNAKGRFLKIAEVGAGGNKSRLTLSMSVAVEFRDYLGDFIEHYAQLGPSQPPDLAQAQDEPRRALKSEFLVRENRKYYMDLKENQRGRFLRIRQTVNRGPGLGSTQGQTIALPAQGLIEFRDALAKLIDDYGVEEE---PAELPEGTSLTVDNKRFFFDVGSNKYGVFMRVSEVKPTYRNSITVPYKVWAKFGHTFCKYSEEMKKIQEKQREKRAACEQLHQQQQQQQEETAAATLLLQGEEEGEED", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P42669-1", "uniprot_id": "PURA_MOUSE", "id": "P42669-1", "name": "Transcriptional activator protein Pur-alpha", "aln": "MADRDSGSEQGGAALGSGGSLGHPGSGSGSGGGGGGGGGGGGSGGGGG-APGGLQHETQELASKRVDIQNKRFYLDVKQNAKGRFLKIAEVGAGGNKSRLTLSMSVAVEFRDYLGDFIEHYAQLGPSQPPDLAQAQDEPRRALKSEFLVRENRKYYMDLKENQRGRFLRIRQTVNRGPGLGSTQGQTIALPAQGLIEFRDALAKLIDDYGVEEE---PAELPEGTSLTVDNKRFFFDVGSNKYGVFMRVSEVKPTYRNSITVPYKVWAKFGHTFCKYSEEMKKIQEKQREKRAACEQLHQQQQQQQEETTAATLLLQGEEEGEED", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P86252-1", "uniprot_id": "PURA_RAT", "id": "P86252-1", "name": "Transcriptional activator protein Pur-alpha", "aln": "------------------------------------------------------------------------------------FLKIAEVGAGGNK--LTLSMSVAVEFRDYLGDFIEHYAQLGPSQPPDLAQAQDEPR--------------YYMDLKENQRG------------PGLGSTQGQTIALPAQGLIEFR-----LIDDYGVEEE---PAELPEGTSLTVDNKRFFFDVGSNK------VSEVKPTYR------------FGHTFCK-------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9V4D9-1", "uniprot_id": "Q9V4D9_DROME", "id": "Q9V4D9-1", "name": "", "aln": "MSDLGSGDD--GISGSKYNVANMEGSSSRNDFDSSAKGGSG---------------VEQELATKMLQIQSKRFYLDVKQNRRGRFIKVAEIGADGRRSQIYLALSTAAEFRDHLSSFSDYYASLGPPNTDNLPEDG-----KLKSEMMIKDYRRYYLDLKENARGRFLRVSQTITR----GGPRSQ-IALPAQGMIEFRDALTDLLEEFGANDGGRFKGDLPEERHMKVDNKNFYFDIGQNNRGVYMRISEVKNNFRTSITIPEKCWIRFRDIFNDYCEKMKKSSD-------------SITAEINLPTSSNSLK----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:*:**:**.*.: : *::*.*.****:*..* ::**.***.:. :*.: **:***** ** *..:.* *******:**** *::::*.:: .:*** :.****.*:**:*.*: :**** .:* * . * . ", "identical_positions": 65, "similar_positions": 50, "identity": "20.0%" }, { "cls_id": "homologset.agr.RGD:1308544", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9DAR0-1", "uniprot_id": "CFA90_MOUSE", "id": "Q9DAR0-1", "name": "Cilia- and flagella-associated protein 90", "aln": "--MEELAKKERRAMDPGGLKKEGKVEEEAGKEEGREEEGGEEEEVTSETLR------------------------GKPRPLPISALPAFSYIP-------PRHQGPKERSYFSREGQTGIVSLYDCVFKRRLDYNQKLHRDDREHAKNLGLHINEEEQERTVPVLMSSVYGKRINQPIEPLNRDYGHVSHVKTDFYRKNEIPSIKGPGFGHINPA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A4QMS7-1", "uniprot_id": "CFA90_HUMAN", "id": "A4QMS7-1", "name": "Cilia- and flagella-associated protein 90", "aln": "--MED-----------------------------------DEEETTASTLR------------------------GKPRPPPVSAQSAFSYIP-------PRRLDPKEHSYYYRPARTGIISLYDCIFKRRLDYDQKLHRDDREHAKSLGLHVNEEEQERPVGVLTSSVYGKRINQPIEPLNRDFGRANHVQADFYRKNDIPSLKEPGFGHIAPS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M0R5R5-1", "uniprot_id": "M0R5R5_RAT", "id": "M0R5R5-1", "name": "", "aln": "KELEGRVKERHKVDAENKAQLLGNDRAQTPGGTQKPDGGTRQEGAASDGPRWREGEGGKGGRGGRRRRGRRGGGGGNYRRNPAGQTPTFAHLSDISFQLHPSTASGPQGAQLLQSRGPGIVSLYDCVFKRRLDYNQKLHRDDREHAKNLGLHINEEEQERTVPVLMSSVYGKRINQPIEPLNRDYGRVNHVRTDFYRKNDIPSIKTPGFGHITPA", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* :* .::. * *: * * . .:*:::. * . : : : .**:*****:*******:************.****:*******.* ** ******************:*:..**::******:***:* ****** *:", "identical_positions": 86, "similar_positions": 34, "identity": "40.0%" }, { "cls_id": "homologset.agr.RGD:1308547", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XTN8-1", "uniprot_id": "CRGNA_DANRE", "id": "Q5XTN8-1", "name": "Gamma-crystallin N-A", "aln": "MSQYSGKIVFFEGKCFTGRRLEVFGDCDNFQDRGFMNRVNSIRVESGAWVCFDHPDFKGQQYMLEKGEYPDFQRWNGHNDHMGSCKPIKMHGEQYRMELFEGQNFTGQCVELCDDCPFLQSTGFSKNCLNSIKVYGDGAWAMYEEPNYRGRMYIVERGNYCAFTEWQSENPNIQSIRRVVNYF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6DGY7-1", "uniprot_id": "CRGNB_DANRE", "id": "Q6DGY7-1", "name": "Gamma-crystallin N-B", "aln": "MSQYSGKICFYEGRCFTGRCLEVYGDCDNFQDRGFMNRVNSIRVESGAWICYDHPDFKGQQYILERGEYPEFQRWNSHNDHMGSCRPIRMHGEQYRMELFEGCNYTGQCMELCDDCPFLQSRGFNTNCVNSVRVFGDGAWVMYEEPNFRGRMYIVERGNYCGHNEWQAQNPHIQSIRRIVNYF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D3ZEG1-1", "uniprot_id": "CRGN_RAT", "id": "D3ZEG1-1", "name": "Gamma-crystallin N", "aln": "MAQRSGKITLYEGKHFTGRKLEVFGDCDNFQDRGFMNRVNSIRVESGAWVCFDHPDFRGQQFILEHGDYPEFFRWNGHNDHMGSCRPVGMHGEHFRIDIFEGCNFTGQCLEFVEDCPFLQSRGWAKSCVNAIKVYGDGAWVLYEEPNYRGRMYVVERGDFRSFSDWEAHSARVQSLRRVLNFF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VHL5-1", "uniprot_id": "CRGN_MOUSE", "id": "Q8VHL5-1", "name": "Gamma-crystallin N", "aln": "MAQRSGKITLYEGKHFTGRKLEVFGDCDNFQDQGFMNRVNSIRVESGAWVCFDHPDFRGQQFILEHGDYPEFFRWNGHNDHMGSCRPVGMHGEHFRIDIFEGCNFTGQCLEFVEDCPFLQSRGWAKSCVNAIKVYGDGAWVLYEEPNYRGRMYVLERGDYRCFSDWGAHSARVQSLRRVLNFF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WXF5-1", "uniprot_id": "CRGN_HUMAN", "id": "Q8WXF5-1", "name": "Gamma-crystallin N", "aln": "MAQRSGKITLYEGKHFTGQKLEVFGDCDNFQDRGFMNRVNSIHVESGAWVCFNHPDFRGQQFILEHGDYPDFFRWNSHSDHMGSCRPVGMHGEHFRLEIFEGCNFTGQCLEFLEDSPFLQSRGWVKNCVNTIKVYGDGAAWSPRSFGAEDFQLSSSLQSDQGPEEATTKPATTQPPFLTANL-", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:* **** ::**: ***: ***:********:*********:******:*::****:***::**:*:**:* ***.*.******:*: ****::*:::*** *:****:*: :*.***** *: ..*:*:::*:**** .. . .. . . : :. . *. * ", "identical_positions": 92, "similar_positions": 51, "identity": "50.27%" }, { "cls_id": "homologset.agr.RGD:1308548", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6ABZ7-1", "uniprot_id": "A0A8I6ABZ7_RAT", "id": "A0A8I6ABZ7-1", "name": "ATP-dependent RNA helicase A", "aln": "MGDIKNFLYAWCGKRKMTPAYEIRAVGNKNRQKFMCEVRVEGFNYAGMGNSTNKKDAQSNAARDFVNYLVRINEVKSEEVPAVGIVPPPPILSDTSDSTASTGEGLPPPMGGPLPPHLALKAAENNSGVESSS----GYGSPG---PTWDRGANLKDYYSRKEEQEVQATLESEEVDLNAGLHGNWTLENAKARLNQYFQKEKIQGEYKYTQVGPDHNRSFIAEMTIYIKQLGRRIFAREHGSNKKLAAQSCALSLVRQLYHLGVIEAYSGLTKKKEGERVEPYKVFLSPDLELQLQNVVQELDLEIVPPP------VDPSMPVILNIGKLAHFEPS-QRQNAVGVVPWSPPQSNWNPWTSSNIDEGPLAYASTEQISMDLKNELAYQMEQDHNLQSVLQERELLPVKKFEAEILEAISQNSVVIIRGATGCGKTTQVPQYILDDFIQNDRAAECNIVVTQPRRISAVAVAERVAYERGEEPGKSCGYSVRFESILPRPHASIMFCTVGVLLRKLEAGIRGISHVIVDEIHERDINTDFLLVVLRDVVLAYPEVRIVLMSATIDTTMFCEYFFNCPIIEVYGRTFPVQEYFLEDCIQMTQFIPPPKDK-KKKDKED------DGGEDDDANCNLICGDEYGPETKLSMSQLNEKETPFELIEALLKYIETLNVPGAVLVFLPGWNLIYTMQKHLENNSHFG-SHRYQILPLHSQIPREEQRKVFDPVPDGVTKVILSTNIAETSITINDVVYVIDSCKQKVKLFTAHNNMTNYATVWASKTNLEQRKGRAGRVRPGFCFHLCSRARFDRLETHMTPEMFRTPLHEIALSIKLLRLGGIGQFLAKAIEPPPLDAVIEAEHTLRELDALDANDELTPLGRILAKLPIEPRFGKMMIMGCIFYVGDAVCTIS-AATCFPEPFISEG--KRLGYIHRNFAGNRFSDHVALLSVFQAWDDARMSGEEAEIRFCEQKRLNMATLRMTWEAKVQLKEILINSGFPEDCLLTQVFTN--TGPDNNLDVVISLLAFGVYPNVCYHKEKRKILTTEGRNALIHKSSVNCPFSSQDMKYPSPFFVFGEKIRTRAISAKGMTLVTPLQLLLFASKKVQSDGQ-IVFIDDWIRLQISHEAAACITALRAAMEALVVEVSKQPNIISQLDPVNEHMLNTIRQISRPSAAGINLMIGS-------VRYGDGPRPPKMARYDNGSGYRRGYGGGGYG---GGGYGGGYGSGGFGGGFGSGGGGGFGGGFNSGGGGGFGSGGGGFGSGGGGFGGGGGGFSGGGGGGGFGGGRGGGGGGGFGGSGGFGSGGGGYGVGGGGYGGGGGSGGYGGGSGGYGGGGGGYGGGEGYNMSPNSYRGNYGGG-GGGYRGGSQGGYRNNFGGD-YRGSSGDYRGS--GGGYRGSGGFQRRGYGGGYFGQGRGGGGGGGGGY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70133-1", "uniprot_id": "DHX9_MOUSE", "id": "O70133-1", "name": "ATP-dependent RNA helicase A", "aln": "MGDIKNFLYAWCGKRKMTPAYEIRAVGNKNRQKFMCEVRVEGFNYAGMGNSTNKKDAQSNAARDFVNYLVRINEVKSEEVPAVGIVPPPPILSDTSDSTASAAEGLPAPMGGPLPPHLALKAEENNSGVESS-----GYGSPG---PTWDRGANLKDYYSRKEEQEVQATLESEEVDLNAGLHGNWTLENAKARLNQYFQKEKIQGEYKYTQVGPDHNRSFIAEMTIYIKQLGRRIFAREHGSNKKLAAQSCALSLVRQLYHLGVIEAYSGLTKKKEGERVEPYKVFLSPDLELQLQNVVQELDLEIVPPP------VDPSMPVILNIGKLAHFEPS-QRQNAVGVVPWSPPQSNWNPWTSSNIDEGPLAYASTEQISMDLKNELTYQMEQDHNLQSVLQERELLPVKKFEAEILEAISSNSVVIIRGATGCGKTTQVPQYILDDFIQNDRAAECNIVVTQPRRISAVAVAERVAYERGEEPGKSCGYSVRFESILPRPHASIMFCTVGVLLRKLEAGIRGISHVIVDEIHERDINTDFLLVVLRDVVLAYPEVRIVLMSATIDTTMFCEYFFNCPIIEVYGRTFPVQEYFLEDCIQMTQFIPPPKDK-KKKDKED------DGGEDDDANCNLICGDEYGPETKLSMSQLNEKETPFELIEALLKYIETLNVPGAVLVFLPGWNLIYTMQKHLENNSHFG-SHRYQILPLHSQIPREEQRKVFDPVPDGVTKVILSTNIAETSITINDVVYVIDSCKQKVKLFTAHNNMTNYATVWASKTNLEQRKGRAGRVRPGFCFHLCSRARFDRLETHMTPEMFRTPLHEIALSIKLLRLGGIGQFLAKAIEPPPLDAIIEAEHTLRELDALDANDELTPLGRILAKLPIEPRFGKMMIMGCIFYVGDAVCTIS-AATCFPEPFISEG--KRLGYIHRNFAGNRFSDHVALLSVFQAWDDARMSGEEAEIRFCEQKRLNMATLRMTWEAKVQLKEILINSGFPEDCLLTQVFTN--TGPDNNLDVVISLLAFGVYPNVCYHKEKRKILTTEGRNALIHKSSVNCPFSSQDMKYPSPFFVFGEKIRTRAISAKGMTLVTPLQLLLFASKKVQSDGQ-IVFIDDWIRLQISHEAAACIT-IRAAMEALVVEVSKQPNIISQLDPVNEHMLNTIRQISRPSAAGINLMIGS-------VRYGDGPRPPKMARYDNGSGYRRGYGGGGYG---GGGYGGGYGSGGFGGGFGSGG--GFGGGFNSGGGG-FGSGGGGFGSGGGGFGGGGGGFSGGGGGG-FGGGRGGGGGG-FGGSGGFGNGGGGYGVGGGGYGGGGG-GGYGGGSGGYGGGG--YGGGEGYSISPNSYRGNYGGG-GGGYRGGSQGGYRNNFGGD-YRGSSGDYRGS--GGGYRGSGGFQRRGYGGGYFGQGRGGGGGGG--Y", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q08211-1", "uniprot_id": "DHX9_HUMAN", "id": "Q08211-1", "name": "ATP-dependent RNA helicase A", "aln": "MGDVKNFLYAWCGKRKMTPSYEIRAVGNKNRQKFMCEVQVEGYNYTGMGNSTNKKDAQSNAARDFVNYLVRINEIKSEEVPAFGVASPPP-LTDTPDTTANAEGDLPTTMGGPLPPHLALKAE-NNSEVGAS-----GYGVPG---PTWDRGANLKDYYSRKEEQEVQATLESEEVDLNAGLHGNWTLENAKARLNQYFQKEKIQGEYKYTQVGPDHNRSFIAEMTIYIKQLGRRIFAREHGSNKKLAAQSCALSLVRQLYHLGVVEAYSGLTKKKEGETVEPYKVNLSQDLEHQLQNIIQELNLEILPPP------EDPSVPVALNIGKLAQFEPS-QRQNQVGVVPWSPPQSNWNPWTSSNIDEGPLAFATPEQISMDLKNELMYQLEQDHDLQAILQERELLPVKKFESEILEAISQNSVVIIRGATGCGKTTQVPQFILDDFIQNDRAAECNIVVTQPRRISAVSVAERVAFERGEEPGKSCGYSVRFESILPRPHASIMFCTVGVLLRKLEAGIRGISHVIVDEIHERDINTDFLLVVLRDVVQAYPEVRIVLMSATIDTSMFCEYFFNCPIIEVYGRTYPVQEYFLEDCIQMTHFVPPPKDK-KKKDKDD------DGGEDDDANCNLICGDEYGPETRLSMSQLNEKETPFELIEALLKYIETLNVPGAVLVFLPGWNLIYTMQKHLEMNPHFG-SHRYQILPLHSQIPREEQRKVFDPVPVGVTKVILSTNIAETSITINDVVYVIDSCKQKVKLFTAHNNMTNYATVWASKTNLEQRKGRAGRVRPGFCFHLCSRARFERLETHMTPEMFRTPLHEIALSIKLLRLGGIGQFLAKAIEPPPLDAVIEAEHTLRELDALDANDELTPLGRILAKLPIEPRFGKMMIMGCIFYVGDAICTIA-AATCFPEPFINEG--KRLGYIHRNFAGNRFSDHVALLSVFQAWDDARMGGEEAEIRFCEHKRLNMATLRMTWEAKVQLKEILINSGFPEDCLLTQVFTN--TGPDNNLDVVISLLAFGVYPNVCYHKEKRKILTTEGRNALIHKSSVNCPFSSQDMKYPSPFFVFGEKIRTRAISAKGMTLVTPLQLLLFASKKVQSDGQ-IVLVDDWIKLQISHEAAACITGLRAAMEALVVEVTKQPAIISQLDPVNERMLNMIRQISRPSAAGINLMIGS-------TRYGDGPRPPKMARYDNGSGYRR--GGSSYS---GGGYGGGYSSGGYGS---------------------------------GGYGG-----------------------------------------------------------------------------SANSFRAGYGAGVGGGYRGVSRGGFRGNSGGD-YRGPSGGYRGS--GGFQRGGG---RGAYGTGYFGQGRGGGGY-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P3F9-1", "uniprot_id": "A0A8M1P3F9_DANRE", "id": "A0A8M1P3F9-1", "name": "RNA helicase", "aln": "MADIKNFLYAWCGKKKLTPNYDIRAAGNKNRQKFMCEVRVESYSYIGMGNSTNKKDAQSNAARDFVNYLVRTKEISPGEVPALGVSVPDG-PSEGGNDDGGGFGNLPS--NCPLPPHLAVKKELESCEGSAPVPGVTGLGYSGRNNAPWERGANLQEYYSKKEEQDAKATYESEEVDLNAGLHGNWTLDNAKARLNQFFQKEKNQTDYKYSQVGPDHNRSFIAEMTIFVRQLGRRVTAREHGSTKKLAAQSCALSLVRQLYHLGVIEAYTGQTKKKEGESVDVYPVNVNDDVQHQLYSVVQELGIHIPPPP------QDPNSPVSLVQGKLAHFEPS-QRQSMAGVVPWSPPQVNWNPWTSSNIDEGPLAFCTPEQISNDLLNELNYQLEQDQNLQTILTERSQLPVKNFQEQIMSTIYNNPVVIIRGATGCGKTTQVPQYILDEFIKGGRASDCNIVVTQPRRISAVSVAERVSFERGEDVGKSCGYSVRFESFLPRPHASILFCTVGVLLRKLESGIRGISHVIVDEIHERDINTDFLLVVLRDVVQAYPDVRVILMSATIDTTMFKEYFFNCPVIEVHGRAHPVQEYFLEDCIQMTQFVPPPMDR-KRKDKDD------EGG-DEDVNCNVICGSEYSPETKRAMSQLNEKETSFELIEALLKYIETLEVPGAVLVFLPGWNLIYSMQKHLEMNPHFG-GHQYRILPLHSQIPREEQRRVFEPVPDGVTKVILSTNIAETSITINDVVFVLDSCKQKVKLFTSHNNMTNYATVWASKTNLEQRKGRAGRVRPGFCFHLCSRARFEKLETHMTPEIFRTPLHEVALSIKLLRLGGIGNFLSKAIEPPPLDAVIEAEHTLRELDALDSNDELTPLGRILAKLPIEPRLGKMMIMGCIFNVGDAVCTIS-AATCFPEPFISEG--KRLGFVHRNFAGSRFSDHVALLSVFQAWDEVRVGGEDAEIRFCEHKRLNMPTLRMTWEAKVQLKEILVNVGFPEECLLNQVFNN--VGPDNNLDLVISLLTFGSYPNVCYHKEKRKILTTEGRNALIHKSSVNCPFSNHDLKYPSPFFVFGEKIRTRAISAKSMTLVSPLQLILFGSKKITSNGE-VVELDDWIKLQIPHDVAAGVAGLRAGLEALVVEVTKDPEYIRNLDPLNERLLNVIRLVSRPSSAGINLMASN-------PRFGDGPRPPKMARTDFGG------GGDFRG---GGGYRGG---GGYRGG-------------------------------GGGYRGG----------------------------------------------------------------------------------GGYQGG-GGGYRGGGGGGYRGYGGGGGYRG-SGGYRGSSGGGGYGGGGRGFRGGGGGGGGGWGGNRGGY-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P24785-1", "uniprot_id": "MLE_DROME", "id": "P24785-1", "name": "Dosage compensation regulator mle", "aln": "-MDIKSFLYQFCAKSQIEPKFDIRQTGPKNRQRFLCEVRVEPNTYIGVGNSTNKKDAEKNACRDFVNYLVRVGKLNTNDVPADAGA------SGGGPRTGLEGAGMAGGSGQQKRVFDGQSGPQDLGEAYRP--------------LNHDGGDGGNRYSVIDRIQEQRDMNEAEAFDVNAAIHGNWTIENAKERLNIYKQTNNIRDDYKYTPVGPEHARSFLAELSIYVPALNRTVTARESGSNKKSASKSCALSLVRQLFHLNVIEPFSGTLKKKKDEQLKPYPVKLSPNLINKIDEVIKGLDLPVVNPRNIKIELDGPPIPLIVNLSRIDSSQQDGEKRQESSVIPWAPPQANWNTWHACNIDEGELATTSIDDLSMDYERSLRDRRQNDNEYRQFLEFREKLPIAAMRSEILTAINDNPVVIIRGNTGCGKTTQIAQYILDDYICSGQGGYANIYVTQPRRISAISVAERVARERCEQLGDTVGYSVRFESVFPRPYGAILFCTVGVLLRKLEAGLRGVSHIIVDEIHERDVNSDFLLVILRDMVDTYPDLHVILMSATIDTTKFSKYFGICPVLEVPGRAFPVQQFFLEDIIQMTDFVPSAESRRKRKEVEDEEQLLSEDKDEAEINYNKVCEDKYSQKTRNAMAMLSESDVSFELLEALLMHIKSKNIPGAILVFLPGWNLIFALMKFLQNTNIFGDTSQYQILPCHSQIPRDEQRKVFEPVPEGVTKIILSTNIAETSITIDDIVFVIDICKARMKLFTSHNNLTSYATVWASKTNLEQRKGRAGRVRPGFCFTLCSRARFQALEDNLTPEMFRTPLHEMALTIKLLRLGSIHHFLSKALEPPPVDAVIEAEVLLREMRCLDANDELTPLGRLLARLPIEPRLGKMMVLGAVFGCADLMAIMASYSSTFSEVFSLDIGQRRLANHQKALSGTKCSDHVAMIVASQMWRREKQRGEHMEARFCDWKGLQMSTMNVIWDAKQQLLDLLQQAGFPEECMISHEVDERIDGDDPVLDVSLALLCLGLYPNICVHKEKRKVLTTESKAALLHKTSVNC--SNLAVTFPYPFFVFGEKIRTRAVSCKQLSMVSPLQVILFGSRKIDLAANNIVRVDNWLNFDIEPELAAKIGALKPALEDLITVACDNPSDILRLEEPYAQLVKVVKDLCVKSAGDFGLQRESGILPHQSRQFSDGGGPPKRGRFETGRFTNSSFGRRGNGRTFGGGYGNN--GGGYGNN-------------------------------GGGYGNIGG--------------------------------------------------------------------------GYGNNAGGYGNN--GGY-GNNGGGYRNN-GGG-YGNNGGGYGNK--RGGFGDSFESNRGSGGGFRNGDQGGRWGNF----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:*.*** :*.* :: * ::** .* ****:*:***:** .* *:*********:.**.********* ::.. :*** . : . .:. . . . . : . : * . : * .. *: : *:* .*:**.:*****::*** *** : *.:: : :***: ***:* ***:**::*:: *.* : *** **.** *::**********:**.*:*.::* ***:.* :. * * :. :: :: .::: *.: : * .* *: : .:: : . :::. .*:**:*** ***.* :.***** ** : :::* * ..* : ::*:: : .* *. **: :. :*: :* .*.****** ********:.*:***::* ..:.. .** *********::*****: ** *: *.: ********.:***:.:*:************:*:**:**:*********:*:*****:***:* :**:::::********: * :** **::** **:.***::**** ****.*:*.. .: *:*: :* :. : : * * :* .:*. :*: :*: *.*.:..***:**** :*:: ::***:**********::: *.*: . ** :*:*** ******:***:**:*** ****:*************:*:*:*:* ** ::****:***:*.*************************** *******: ** ::***:*******:**:*******.* :**:**:****:**:**** ***: .**:*********:**:******:****::*.:* .* :. :: :: *.* * : :**. :: ::*.: *****:: . * * : **. * ***: * *:*.*:.: *:** ** ::* : ****:*::.: . : * * **: ::** :* ***:* ******:****.: **:**:**** *. :.:* *************:*.* :::*:***::**.*:*: .: :* :*:*:.::* : ** : ::..:* *:. . .:* * .*: :::: :: :. *:..:.* . ::.** *** .* : * * . **** .. **: . **: . ..* . *** * . **:*. **. * . .*.* .. * .. * . * * . * ", "identical_positions": 580, "similar_positions": 379, "identity": "40.45%" }, { "cls_id": "homologset.agr.RGD:1308550", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZLT1-1", "uniprot_id": "D3ZLT1_RAT", "id": "D3ZLT1-1", "name": "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7", "aln": "MGAHLTRRYLWDASVEPDPEKMPSFPPNYGLPERKERVMVATQQEMMDAQLTLQQRDYCAHYLIRLLKCKRDSFPNFVACKHEQHDWDYCEHQDYVKRMKEFERERRLLRRKKRRELREQRVAQGQGEGEVGPEMAL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CR61-1", "uniprot_id": "NDUB7_MOUSE", "id": "Q9CR61-1", "name": "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7", "aln": "MGAHLTRRYLWDASVEPDPEKIPSFPPDLGFPERKERVMVATQQEMMDAQLTLQQRDYCAHYLIRLLKCKRDSFPNFLACKHEQHDWDYCEHLDYVKRMKEFERERRLLQRKKRRALKEARVAQGQGEGEVGPEVAL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P17568-1", "uniprot_id": "NDUB7_HUMAN", "id": "P17568-1", "name": "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7", "aln": "MGAHLVRRYLGDASVEPDPLQMPTFPPDYGFPERKEREMVATQQEMMDAQLRLQLRDYCAHHLIRLLKCKRDSFPNFLACKQERHDWDYCEHRDYVMRMKEFERERRLLQRKKRREKKAAELAKGQGPGEVDPKVAL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VXZ0-1", "uniprot_id": "Q9VXZ0_DROME", "id": "Q9VXZ0-1", "name": "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7", "aln": "MGNALT--HYMKPDVMPGPDVVPTFDPLLGFKSRKERVMIATQEEMESAKLPLEFRDYCAHLAIAYQACRSDTFPFVYKCAHQKHEYLTCEYEDYVLRMKEFERERRLLERQKRLN-KAA-----------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** *. : ...* *.* :*:* * *: .**** *:***:** .*:* *: ****** * *: *:** . * :::*:: **: *** ************.*:** : ", "identical_positions": 56, "similar_positions": 27, "identity": "40.88%" }, { "cls_id": "homologset.agr.RGD:1308551", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JST1-1", "uniprot_id": "A0A0G2JST1_RAT", "id": "A0A0G2JST1-1", "name": "Adhesion G-protein coupled receptor G6", "aln": "MMFDTRGRRCCHWRQKSSTLLFLFALCV-ACFPLPVWGCGNCRLVLSNPSGTFTSPCYPNDYPNTQSCSWTLRAPTGYIIQITFNDFDIEEAPNCIYDSLSLDNGESQTKFCGATAKGLSFNSSVNEMHVSFSSDFSIQKKGFNASYIRVAVSLRNQKVILPQTLDAYQVSVAKSISIPELKAFTLCFEASKVGNEDDDWTAFSYSDKSLTQLLSLEKANNGYFLSISGARCLLNNALPVKEKEDIFTGNFEQLCLVWNNSWGSVGINFKKNYETIPCDLTIGTVVPGDGTLLLGSDRDEIASLK-----GSVYNFRLWNFTMDPKSLSNLSCSMSGNVIDWHNDFWSISTQALKAENNLSCGSYLIPLPAAELTNCSDLGTLCQATVSPPTPPSPIVTTNIPVTNRIRKQKNDGIMYRISVVIHNDLNHPEVRVQSKVAEWLNATFQNWNYTVYVVNISFHQDLGEDRMKVKRDVMDDDKRLVLWALLVYNATNNVSLNGEMIEQKLSANNASLEDGIRLCKVDVKQLGMCNTLGDPEGFKWTAISPSV-YKQPCPNKPGFFMMRTCLCNETS---TFWGPIDASNCS---------RQSNEVANEILDLTGDGQNLTSANINSIVEQVKRIVNKEENIDRTLGSTLMNIFSNILSSSDSNLLESSTEALKTIDELAFKIDLNSTPHVNIETQNLALGVSSLMPGTNAPSNFSIGLPSNNDSYFQMDFENGQADPLASVILPPNLLENLSPEDSILVRRAQFTFFNKTGLFQDVGSQRKILVSYVMACSIGNITIQNLKDPVQIKIKHTRTQEVHQPICAFWDLNQNKSFGGWNTSGCVAHSDSDAGETICLCNHFTHFGVLMDLPRSASQIDGRNTKVLTFITYIGCGISAIFSAATLLTYVAFEKLRRDYPSKILMNLSSALLFLNLIFLLDGWITSFGVAGLCTAVAALLHFFLLATFTWMGLEAIHMYIALVKVFNTYIHRYILKFCIIGWGLPALVVSIILVSRKQNEVYGKESYGKDQD----DEFCWIQDPVVFYVSCAGYFGIMFFLNVAMFIVVMVQICGRNGKRSNRTLREEVLRNLRSVVSLTFLLGMTWGFAFFAWGPLNIPFMYLFSIFNSLQGLFIFIFHCAMKENVQKQWRRHLCCGRFRLADNSDWSKTATN-IIKKSSDNLGKSLSSSSIGSNSTYLTSKSKSSSTTYFKRNSHSDSTSMDKSLSKLTHAGGEQTSIIPVHQVIDKVKGYCNAHSDNFYKNIILSDAFSHSTKF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6F3F9-1", "uniprot_id": "AGRG6_MOUSE", "id": "Q6F3F9-1", "name": "Adhesion G protein-coupled receptor G6", "aln": "MMFDTLGKRCCPWRLKPSALLFLFVLCV-TCVPLSVCGCGSCRLVLSNPSGTFTSPCYPNDYPNTQSCSWTLRAPAGYIIQITFNDFDIEEAPNCIYDSLSLDNGESQTKFCGATAKGLSFNSSVNEMHVSFSSDFSIQKKGFNASYIRVAVSLRNQKVILPQTLDAYQVSVAKSISIPELKAFTLCFEASKVGNEGGDWTAFSYSDESLTQLLSLEKASNGYFLSISGSRCLLNNALPVKDKEDIFTENLEQLCLVWNNSWGSIGINFKKNYETVPCDSTISAVVPGDGTLLLGSDRDEVASLR-----GSIYNFRLWNFTMDLKALSNLSCSVSGNVIDWHNDFWSISTQALKAEGNLSCGSYLIQLPAAELTNCSELGTLCQ----------------------------DGIMYRISVVIHNDFNHPEVKVQTKVAEWLNSTFQNWNYTVYVVNISFHQKVGEDRMKVKRDIMDDDKRLVLWALLVYNATNNVSLNEEKIKQKLMTNNASLEDGLRLCEVDVNQLGMCSALEDPDGFSWPATLPSV-YKQPCPNKPGFFMTRACLSNGTS---TFWGPVDTSNCS---------RQSNEVANEILNQTGDGQNLTSANINSIVEKVKRIVNKEENIDITLGSTLMNIFSNILSSSDSDLLESSTEALKTIDELAFKIDLNSTPHVNIETQNLALGVSSLIPGTNAPSNFSIGLPSNNESYFQMDFGNGQTDPLASVILPPNLLENLSPEDSVLVRRAQFTFFNKTGLFQDVGSQRKVLVSYVMACSIGNITIQNLKDPVQIKIKHTRTQEVHHPICAFWDMNKNKSFGGWNTSGCVAHSDLDAGETICLCSHFTHFGVLMDLPRSASQIDGRNTKVLTFITYIGCGISAIFSAATLLTYVAFEKLRRDYPSKILMNLSSALLFLNLIFLLDGWVTSFGVAGLCTAVAALLHFFLLATFTWMGLEAIHMYIALVKVFNTYIHRYILKFCIIGWGLPALVVSIILVSRRQNEVYGKESYGKDQD----DEFCWIQDPVVFYVSCAGYFGVMFFLNVAMFIVVMVQICGRNGKRSNRTLREEVLRNLRSVVSLTFLLGMTWGFAFFAWGPLNIPFMYLFSIFNSLQGLFIFIFHCAMKENVQKQWRRHLCCGRFRLADNSDWSKTATN-IIKKSSDNLGKSLSSSSIGSNSTYLTSKSKSSSTTYFKRNSHSDNFS-------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86SQ4-1", "uniprot_id": "AGRG6_HUMAN", "id": "Q86SQ4-1", "name": "Adhesion G protein-coupled receptor G6", "aln": "MMFRSDRMWSCHWKWKPSPLLFLFALYI-MCVPHSVWGCANCRVVLSNPSGTFTSPCYPNDYPNSQACMWTLRAPTGYIIQITFNDFDIEEAPNCIYDSLSLDNGESQTKFCGATAKGLSFNSSANEMHVSFSSDFSIQKKGFNASYIRVAVSLRNQKVILPQTSDAYQVSVAKSISIPELSAFTLCFEATKVGHEDSDWTAFSYSNASFTQLLSFGKAKSGYFLSISDSKCLLNNALPVKEKEDIFAESFEQLCLVWNNSLGSIGVNFKRNYETVPCDSTISKVIPGNGKLLLGSNQNEIVSLK-----GDIYNFRLWNFTMNAKILSNLSCNVKGNVVDWQNDFWNIPNLALKAESNLSCGSYLIPLPAAELASCADLGTLCQATVNSPSTTPPTVTTNMPVTNRIDKQRNDGIIYRISVVIQNILRHPEVKVQSKVAEWLNSTFQNWNYTVYVVNISFHLSAGEDKIKVKR-SLEDEPRLVLWALLVYNATNNTNLEGKIIQQKLLKNNESLDEGLRLHTVNVRQLGHCLAMEEPKGYYWPSIQPSE-YVLPCPDKPGFSASRICFYNATNPLVTYWGPVDISNCL---------KEANEVANQILNLTADGQNLTSANITNIVEQVKRIVNKEENIDITLGSTLMNIFSNILSSSDSDLLESSSEALKTIDELAFKIDLNSTSHVNITTRNLALSVSSLLPGTNAISNFSIGLPSNNESYFQMDFESGQVDPLASVILPPNLLENLSPEDSVLVRRAQFTFFNKTGLFQDVGPQRKTLVSYVMACSIGNITIQNLKDPVQIKIKHTRTQEVHHPICAFWDLNKNKSFGGWNTSGCVAHRDSDASETVCLCNHFTHFGVLMDLPRSASQLDARNTKVLTFISYIGCGISAIFSAATLLTYVAFEKLRRDYPSKILMNLSTALLFLNLLFLLDGWITSFNVDGLCIAVAVLLHFFLLATFTWMGLEAIHMYIALVKVFNTYIRRYILKFCIIGWGLPALVVSVVLASRNNNEVYGKESYGKEKG----DEFCWIQDPVIFYVTCAGYFGVMFFLNIAMFIVVMVQICGRNGKRSNRTLREEVLRNLRSVVSLTFLLGMTWGFAFFAWGPLNIPFMYLFSIFNSLQGLFIFIFHCAMKENVQKQWRQHLCCGRFRLADNSDWSKTATN-IIKKSSDNLGKSLSSSSIGSNSTYLTSKSKSSSTTYFKRNSHTDNVSYEHSFNKS------------------------GSLRQCFHGQVLVKTGPC-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "C6KFA3-1", "uniprot_id": "AGRG6_DANRE", "id": "C6KFA3-1", "name": "Adhesion G protein-coupled receptor G6", "aln": "-MISFISGRWWRWKFQNTLAVFLLLICLSTSVAQSCQSSTSCNVVLTDSQGSFTSPCYPNDYPPSQSCNWTIQAPAGFIVQITFLDFELEEAQGCIYDRVVVKTGTSDAKFCGLTANGLTLNSTGNVMEVFFNSDFSVQKKGFHISYKQVAVTLRNQKVTMPKSSKTILR-VSNSISIPVLTAFTVCFEIARTAQKAT-ETIFTLSDAAGTSILAFEKTSNGMELFIGASYCSVDNLLTSSD----ITATMKPLCLTWTKSSGLIGVYFGGHYFSSICSASQIYTLQSGGLLQIAGKGSSSVSVDDQNLDGFIYNFRLWDHAMLSSELSALTCDTVGNVVDWDHSYWTIPGSSTQTDSTLSCSTAITTLSPGTAGCASGLGCPATLTVTITS----IATTNIIPTN---ATTHEDIFYRSTLVVT-DEQTPDRDATAIISQWLNQTFQNWMYRVYVDGISLQLITVLSRITTTR--------QTYLALLVYKNTTDVNLAEVEIESMLR-SAPAIGNGLTLDSVTVNLMENCQADEFPVHYRWPESRPTVTQYVPCFPYKDRNASRTCMINRDN-YTSFWALPDRGNCTNITSITVSQENAMDVAVQLADISNNG--LSKEELTQVVTKVMELVN-IAKINATLASTVVTIISNVMVSSEDAQKDASETALKAVDELVQKIEFDG-PSLTISSKNLVVGVSALDTTNFNGSTLSAFIATN-TTDPQIDFDSEAHNALAVVTLPPTLLQNLSLSQIEKVSRINFMFFGRTGLFQDHQNNGLTLNSYVVASSVGNFTIKNLQDPVRIEIAHLEYQKDPNPQCVFWDFNLQNYSGGCNSDGCKVGSDSNSNRTVCLCNHLTHFGILMDVSRAAELIDEKNNRVLTFITYIGCGISAIFSAATLLTYIAFEKLRRDYPSKILMNLSTSLLFLNMVFLLDGWLASYEIKELCVTVAVFLHFFLLTSFTWMGLESIHMYIALVKVFNTYIRRYILKFCIVGWGVPAAIVGIVLAVSKDS--YGKNYYGKGKDGQGTSEFCWILNPVVFYVTCVAYFSIIFLMNVAMFIVVMIQICGRNGKRSNRTLREDILRNLRSVVSLTFLLGMTWGFAFFAWGPVSLAFMYLFTIFNSLQGLFIFVFHCALKENVQKQWRRYLCCGKLRLADNSDWSKTATNNTKKVSSDNLGKSLSSSSFGSTTANWTSKAKATLNP-FARHSNADSTLQ------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: *: : : :**: : : ... . .. .*.:**::..*:*********** :*:* **::**:*:*:**** **::*** .**** : :..* *::**** **:**::**: * *.* *.****:*****: ** :***:****** :*:: .: *::***** *.***:*** ::..:: * *: *: : *.:*:: *:..* * *. : * ::* *. .: :: .:: ***.*.:* * :*: * :* : *. : .: ..* * :... .. .*: * :******:.:* . ** *:*. ***:**.:.:*.*. : :::..***.: : *... .: ** . :.*:** ::*: . *: . : :::*** ***** * *** .**:: .::...* . *****: *.:..* *:. * . :: :*: * * *. : * : * : *. *: ** . * *: * . ::*. * .** .:: :** :: : : :* *:. ::..:* :* .:** :*: **.**::.*:**:: **:. ::* ***::***. **:::. . :.* ::**.:.**:* . . *.:* :.:* : *:** . :.** * ***.**:*** .: * * :* **.:****** : * ***:*.*:**:**:**:***:*:* * . *: :* *.***:* :: ** *:.** . * ::..*:***.*:****:***:.*:*. :* :*.:*****:******************:******************::*****::******::*: : ** :**.:******::*******:***************:********:***:** :*.::*. .:. ***: *** :. .***** :**:***:*..**.::*::*:*******:****************::***************************:.:.*****:***********:****:*********::****::************** * *************:**.:: ***:*:: .. * *:*::*. ", "identical_positions": 536, "similar_positions": 354, "identity": "42.14%" }, { "cls_id": "homologset.agr.RGD:1308552", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4ABB2-1", "uniprot_id": "D4ABB2_RAT", "id": "D4ABB2-1", "name": "", "aln": "-----MNTSCWKSITQRPALPTAGPQQSAMTREGQ-FREELGYDRMPTLERGRQD--------AGRQDTGSYTPDTKPKDLQLTKR--LPPCFSYKTWVFSVLMGSCLLVTSGFSLYLGNVFPSEMDYLRCAAGSCIPSAIVSFAVGRRNVSAIPNFQILFVSTFAVTTTCLIWFGCKLILNPSAININFNLILLLLLELLMAATVIISARSSEEPCKKKKVGLPQLPPHAPEGSISDGTNILDEVTFPARVLKSYSVVEVIAGVSAVLGGVIALNVEEAVSGPHLSVTFFWILVACFPSAIASHVTAECPSKCLVEVLITISSLTSPLLFTASGYLSFSVMRIVEIFKDYPPDIK-SYDVLLLLLLLLLLLQGGLNTGTAIQCVSFKVSARLQAASWDSQSCPQERPAGEVVRSPLKEFDKEKAWRAVVVQMAQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VHK5-1", "uniprot_id": "MLC1_MOUSE", "id": "Q8VHK5-1", "name": "Membrane protein MLC1", "aln": "-----------------------------MTREGQ-FREELGYDRMPTLERGRQD--------AGRQDPGSYTPDSKPKDLQLSKR--LPPCFSYKTWVFSVLMGSCLLVTSGFSLYLGNVFPSEMDYLRCAAGSCIPSAIVSFAVGRRNVSAIPNFQILFVSTFAVTTTCLIWFGCKLILNPSAININFNLILLLLLELLMAATVIISARSSEEPCKKK------------KGSISDGSNILDEVTFPARVLKSYSVVEVIAGVSAVLGGVIALNVEEAVSGPHLSVTFFWILVACFPSAIASHVTAECPSKCLVEVLIAISSLTSPLLFTASGYLSFSVMRVVEIFKDYPPAIK-SYDVLLLLLLLLLLLQGGLNTGTAIQCVSFKVSARLQAASWDPQSCPQERPAGEVVRGPLKEFDKEKAWRAVVVQMAQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15049-1", "uniprot_id": "MLC1_HUMAN", "id": "Q15049-1", "name": "Membrane protein MLC1", "aln": "-----------------------------MTQEP--FREELAYDRMPTLERGR-------------QDPASYAPDAKPSDLQLSKR--LPPCFSHKTWVFSVLMGSCLLVTSGFSLYLGNVFPAEMDYLRCAAGSCIPSAIVSFTVSRRNANVIPNFQILFVSTFAVTTTCLIWFGCKLVLNPSAININFNLILLLLLELLMAATVIIAARSSEEDCKKK------------KGSMSDSANILDEVPFPARVLKSYSVVEVIAGISAVLGGIIALNVDDSVSGPHLSVTFFWILVACFPSAIASHVAAECPSKCLVEVLIAISSLTSPLLFTASGYLSFSIMRIVEMFKDYPPAIKPSYDVLLLLLLLVLLLQAGLNTGTAIQCVRFKVSARLQGASWDTQNGPQERLAGEVARSPLKEFDKEKAWRAVVVQMAQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32T7H1-1", "uniprot_id": "A0AB32T7H1_DANRE", "id": "A0AB32T7H1-1", "name": "", "aln": "MHYLGTASSLLRCVPVAVYVIHWCLMDLRMQREEASAQEVFSYAQMSTLERNSGVGTLSRHLERERLERDGYTVDVRASDLQLDQPGPLHPCFSYRVWLYSVVVGSSLLIASAFSLYMGNVFPAAMDYLRCTAGSSIPAAVVSFAIAKNRQVAVSDFQLVYVSSFAVTTTCLVWFGCKLAISPSAININFNLLLLIVLEVLTASTVILSARSVDNCCSHS-------------KPVSEGPMIVTQTSFPTRLFKAFAVIELIVGIAAVFGGIIALNLGALLPEPYLSVTFFWILAACFPSAIASHVVAENPSKSLVEMLIAINSVTSPLLFSASAFLSSSVISFIEIFLHEVALAKQSYDILLLVLMLLLLVPAVLTLATIIQCASYKSQVRMGANEWDTLR--KKHCEQLASNGTLRDFDKEKAWKAVVVQMAQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :* :* :.* :*.****. : .*: * :..**** : * ****::.*::**::**.**::*.****:*****: ******:***.**:*:***::.:.. .:.:**:::**:********:****** :.**********:**::**:* *:***::*** :: *.:. .:*:.. *: :..**:*::*:::*:*:*.*::**:**:****: :. *:*********.***********.** ***.***:**:*.*:******:**.:** *:: .:*:* . . * ***:***:*:*:**: . *. .* ***. :* ..*: . .**. ::: . ...*::*******:********", "identical_positions": 193, "similar_positions": 129, "identity": "44.37%" }, { "cls_id": "homologset.agr.RGD:1308553", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4AD66-1", "uniprot_id": "D4AD66_RAT", "id": "D4AD66-1", "name": "", "aln": "MPMSSRGRDLHPGHHHFGPCSPLTQFWPGP-EPQSVKGLYYRRARKVSTL-DASPEANLKEILVNVGGQRYLLPWSTLDAFPLSRLSRLRLCRSYEEITQLCDDYDENSQEFFFDRNPSAFGVIVSFLAAGKLVLLREMCALSFREELSYWGIEEANLERCCLRKLLKKLEEAAELRREE-AAQRQQQRQACHSEVQASRWARSMNQLREMVEDPQSGLPGKVFACLSVLFVATTAVSLCVSTMPDFRAEEDKGECARKCYYIFVVETICVAWFSLEFCLRFVQAPNKCQFFRGPLNVIDILAISPYYVSLAVSDE--SPEAGERPSGSS--YLEKVGLVLRVLRALRILYVMRLARHSLGLQTLGLTVRRCAREFGLLLLFLGVAVTLFSPLVYVAENESGR-----VLEFTSIPASYWWAIISMTTVGYGDMVPRSVPGQMVALSSILSGILIMAFPATSIFHTFSHSYLELKREQEQVQ--ARLRRLQNN----------------NSASERELLSDVDDLAPEDLTSPGRYM---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80XM3-1", "uniprot_id": "KCNG4_MOUSE", "id": "Q80XM3-1", "name": "Voltage-gated potassium channel regulatory subunit KCNG4", "aln": "MPMSSRDRDLHPGHHHFGSCSPLSQLWPGP-EPKSVKGLYYSRARKVGNQ-DASPEANLKEILVNVGGQRYLLPWSTLDAFPLSRLSRLRLCRSHEEITQLCDDYDEDSQEFFFDRNPSAFGVIVSFLAAGKLVLLREMCALSFREELSYWGIEETNLERCCLRKLLKKLEEAAELRREE-AAQRQQQRQACHSEVQASRWARSMNQLREMVEDPQSGLPGKVFACLSVLFVATTAVSLCVSTMPDFRAEEGKGECTRKCYYIFVVESICVAWFSLEFCLRFVQAPNKCQFFRGPLNVIDILAISPYYVSLAVSDE--SPEAGERPSSSS--YLEKVGLVLRVLRALRILYVMRLARHSLGLQTLGLTVRRCAREFGLLMLFLAVAVTLFSPLVYVAENESGR-----VLEFTSIPASYWWAIISMTTVGYGDMVPRSVPGQMVALSSILSGILIMAFPATSIFHTFSHSYLELKREQEQVQ--ARLRRLQNT----------------NSASERELLSDVDDLVPEGLTSPGRYM---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TDN1-1", "uniprot_id": "KCNG4_HUMAN", "id": "Q8TDN1-1", "name": "Voltage-gated potassium channel regulatory subunit KCNG4", "aln": "MPMPSRDGGLHPRHHHYGSHSPWSQLLSSPMETPSIKGLYYRRVRKVGAL-DASPVDLKKEILINVGGRRYLLPWSTLDRFPLSRLSKLRLCRSYEEIVQLCDDYDEDSQEFFFDRSPSAFGVIVSFLAAGKLVLLQEMCALSFQEELAYWGIEEAHLERCCLRKLLRKLEELEELAKLHREDVLRQQRETRRPASHSSRWGLCMNRLREMVENPQSGLPGKVFACLSILFVATTAVSLCVSTMPDLRAEEDQGECSRKCYYIFIVETICVAWFSLEFCLRFVQAQDKCQFFQGPLNIIDILAISPYYVSLAVSEE--PPEDGERPSGSS--YLEKVGLVLRVLRALRILYVMRLARHSLGLQTLGLTVRRCTREFGLLLLFLAVAITLFSPLVYVAEKESGR-----VLEFTSIPASYWWAIISMTTVGYGDMVPRSVPGQMVALSSILSGILIMAFPATSIFHTFSHSYLELKKEQEQLQ--ARLRHLQNTGPASECELLDP-----HVASEHELMNDVNDLILEGPALPIMHM---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B1J1-1", "uniprot_id": "A0A8M3B1J1_DANRE", "id": "A0A8M3B1J1-1", "name": "", "aln": "MPIISNANHDFSNLSVSTDDSSLDLFFTEIPETETIKGVYFQRAQRLCGISTLKDVDHSKLALINVGGDRYTFPWSTLDEFPLSRLGQLRHCSSPDDIAQLCDDYDEARREFFFDRSSVAFRVILNFLAAGKLRLLRQVCAVSLSDELTYWGIDPVHMERCCRRKLLSRVEDVAEKKKKE-DERKQKRHALQRPLAQDKGFIRLMNRLQEIVENPHSGWAGKLFACFSVVMIAVTVISLCISTLPDH---ENRGECTEKCRNIFIVETVCVAWFSMEFLLRFLQAESKMQFLRNPLNVIDVIAILPYYISLVVDSEDTSDEAELNGAGTSRGYLDKLGLILRVMRALRILYVMRLARHSLGLQTLGLTMQRSMREFGLLLLFLCVAVALFSPLVHLAEKEFSKGKATGPNSFSSIPASYWWAIISMTTVGYGDMVPYSIPGQVVAFSSILSGILIMAFPATSIFHVFSRSYHELKREQEMIYKEERVAILDATAKEDAQRLLKRDSFSWAIANRNSLRKDNGTAAIQPTLTAAACCKDI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: *. .. *. : . *. ::**:*: *.::: . * *:**** ** :****** ******.:** * * ::*.******** :******.. ** **:.******* **:::**:*: :**:****: .::**** **** ::*: * : . :::: :. : . : **:*:*:**:*:** .**:***:*::::*.*.:***:**:** *.:***:.** **:**::******:** ***:** .* **::.***:**::** ***:**.*..* . * . :.:* **:*:**:***:************************::*. ******:*** **::******::**:* .: .*:*********************** *:***:**:*******************.**:** ***:*** : *: *: . *....* .* . : . ", "identical_positions": 263, "similar_positions": 131, "identity": "48.79%" }, { "cls_id": "homologset.agr.RGD:1308555", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U2Y9-1", "uniprot_id": "LCA5_RAT", "id": "Q5U2Y9-1", "name": "Lebercilin", "aln": "------------------------------------------MGERDQSSDTDQERKGGKHPYSS-------HYSSDFGSSPQSSGPSSPVN--TPPCASNREKNPKRHLSDHHVRHQTVRKVSPKAIPNKKGVRVGFRSQSLNREPLRKDPDIVTKRVLSARLLKITELQNEVSELQVKLAQLLKENKALKSLQYRQEKALSKFEDAENEISQLIHRHNGEITALKERLRKSQEKERMAEKRVKDTEGELFRTKFSLQKLKKISEARHLPERDDLAKKLVSAELKLDNTERKIKELSKNLELSTNSFQRQLLAERKRAFEAHDENKILQKELQRLHHKLKEKEKELDIKNIYANRLPKSSPKKEKEIAR-KHASCQSDFTDLCTKAVQTAEDFEPEEFPFTAQTVLCYENRWDGSEYLPSYLEYQERNEHGSE-SLSSTLEQEGKYSDDQDSCTAKQETGKSECEWERE-------ELDK-VKGKSSLLGRTEKLVLEAGSVQTESYQAQTIDKFQ-DEAERLKTEMLLAKLNEINKELQDP--------QSLSRPLLPLLPNFESKLYSPDR---SLRPYTFSESLDRSFNGQHLSDMSFLTPRDEG------QSPGLIRSPAPSD--EFSFGSYVPSFGKTPGKSNPPSQKNSLLDFQSNMSEGLSKDSLDFISRK-EKKATLMEQLFGTSASASATNTSASTTTNTTTNTNTNTNTNTNTNCNVPSKSIDSHFPAASRGDLDPLHFLSGDRSSRVREPDGEDEDLFLSEGRSFNPNRHRLKHTSTKPTVTAVDSIDEDIEEVTLR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80ST9-1", "uniprot_id": "LCA5_MOUSE", "id": "Q80ST9-1", "name": "Lebercilin", "aln": "------------------------------------------MGERARSPDIEQGKKGGKHPYS--------HYSSDLGSSPQSSGPSSPVN--TTPCASTREKNPKRHLSDNQVHHPTVRKVSPKAVPSKKGIRVGFRSQSLNREPLRKDPDIVTKRVLSARLLKINELQNEVSELQVKLAQLLKENKALKSLQYRQEKALNKFEDAENEISQLIHRHNNEITALKERLRKSQEKERATEKRVKETEGELFRTKFSLQKLKKISEARHLPERDDLAKKLVSAELKLDDTERKIKELSKNLELSTNSFQRQLLAERKRAFEAYDENKVLQKELQRLHHKLKEKEKELDIKNIYANRLPKSSPKKEKEIER-KHVSCQSDFTDQCTKGVQTAEDFELEDFPFTAQTVLCYENRWDEPEYLSSYLEYQDLNKHGSE-MLSSVLGQEGKYDEDEDPCSAKQEARKPESEWARE-------ELDK-VKGKSALLGRAEKLALEAGRFPTENYQAQSVDKFE-DEAERLKTEMLLAKLNEINKELQDP--------QNLGRAPLPLLPNFESKLHSPDR---STRPYSFPESLDRSFNGQHLQDLSFLTPRGEGGSPGPIRSPGQIRSPAPLD--EFSFGSYVPSFGKTLGKSNPPSQKSSLLDFQSNSSESPSKDSLDLMSRK-EKKATLMEQLFGPSAS----------------------------NTSVSSKSTDPHFPAASRGDMDPLHFLSGDRNSRVREPGDEEEDLFLREGRSFNPNRHRLKHASNKPTVTAVDSVDEDIEEVTLR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86VQ0-1", "uniprot_id": "LCA5_HUMAN", "id": "Q86VQ0-1", "name": "Lebercilin", "aln": "------------------------------------------MGERAGSPGTDQERKAGKHHYS---------YLSDFET-PQSSGRSSLVS--SSP-ASVRRKNPKRQTSDGQVHHQAPRKPSPKGLPNRKGVRVGFRSQSLNREPLRKDTDLVTKRILSARLLKINELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLIFRHNNEITALKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKEISEARHLPERDDLAKKLVSAELKLDDTERRIKELSKNLELSTNSFQRQLLAERKRAYEAHDENKVLQKEVQRLYHKLKEKERELDIKNIYSNRLPKSSPNKEKELALRKNAACQSDFADLCTKGVQTMEDFKPEEYPLTPETIMCYENKWEEPGHLTLDLQSQKQDRHGEAGILNPIMEREEKFVTDEELHVVKQEVEKLEDEWERE-------ELDKKQKEKASLLEREEKPEWETGRYQLGMYPIQNMDKLQGEEEERLKREMLLAKLNEIDRELQDS--------RNLKYPVLPLLPDFESKLHSPER---SPKTYRFSESSERLFNGHHLQDISFSTPKGEG------QNSGNVRSPASPN--EFAFGSYVPSFAKTSERSNPFSQKSSFLDFQRNSMEKLSKDGVDLITRK-EKKANLMEQLFGASGS-----------------------------STISSKSSDPNSVASSKGDIDPLNFLPGNKGSRDQE-HDEDEGFFLSEGRSFNPNRHRLKHADDKPAVKAADSVEDEIEEVALR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9QG33-1", "uniprot_id": "LCA5_DANRE", "id": "E9QG33-1", "name": "Lebercilin", "aln": "MDLHEDNQESEHSRLSHHNERKILESLRSGKQENNGKDMGNSAGDHAQSRTRETAGDPGRNGFSDGERSSGSFYSDDYENASHSDRSLSPSASPSPPRRGRSRRVSSSPLHKTGVHKGASRRILSHSHHPQQ-RAGAIRSQSLSKDAPSKEVDQVTKRMLSARLLKINELKNALSELRLHADELQRENRLLRQLQLRQEKALHRYNDTDSEISQLLARHNNETHVLRERLRRSQENQRTAERSLRERDAQLQRCRSQMQKLQQLADDQNLGEREELSRKLIGTQSRLQDSEHRVKELEKNMELSSGSFQRQLANERRKTHDAQQEVKALQEEVERLCTKLKEKERELDARNIYANRMHKASSRKEAENGS-----KRKGFNITSTKAVQTEDRTSSLDFPSPPPALTNNLPPDDQTDDYLSLKDQQSREHRTRESKEWKIQEFWREREKERHMESAREQEKEKETLHERERQTELLKDVERQRLDQDLSSNEKNFKGNRVGLNREEEDRRIGMSVSQKEEEIQKQRELEEEQQKVRNREIQDYNQERVEEERQRKEQLLAKMREIDIQTQGQDSDFFSDDTGSVRSPPRLSEQRNHNGFFKLTEPDENINTFSSGRRGGSLRAQAPNEDLDLAFGSYAPSFGKSTPRAGLGTRN------AQNHSPRELDEGLDLGGLVKERKSNLMQQLFGATAT---------------------------------------PPPSDPSSKMEILSPPLTTQFSGRRRDTDTPNELNIS---SLPNNRSTLQVSESRPAVRAITSFDDDIEELTL-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VVD0-1", "uniprot_id": "Q9VVD0_DROME", "id": "Q9VVD0-1", "name": "Lebercilin domain-containing protein", "aln": "-----------------------------------------------------------------------------MVSPRKLASSYGPRVSQSEPNNLMAASAKSCESLFSASSRESASLIYQRSKPPPPQQRGGVKG---SGSMSSQNHSEIHQRVMSARNLRAKTFQNQLADAQAEIANLAHENRMLRTLHNRQSSALNKYEAHNAELPKLLSSHAEELRMWQTKYRKLQAANKALELKLKQKEEIILTLSDQNKHYSQLNKDKNLDERQKLQEKLKSLEQRLEEKDNDMKLMARKVQLESKNIRQQLLNEQRKGKEVMLKLEKAKLEIS--------GYRKLEEYTLGTDKVNPLSSGRRTKLSG---VTDEPDKIDKLEKSMEMLDKAIEKNNQSEFTALTDVME----SESFYDFEKDSAEDKSGPNTPPSQIERQVGGRGGKLILPPATNHAKMGQKANRST---------------LSQVLSAQGKISVSSGKSAKSRIAVAVPKMESVQVSKRREPETVSRLASAETKPKQKP---------------LEYEYEDDYEPAGEDG---DDDAYGMMSKMCEGEEPQDNSEENANE-------------SSLLKYSAYMDNKSSEGDPLEESMEEYDGTDG-------------QQSQGSDDEDISVRAPRLKENMSSLRKQISNDFK-------------------------------------------ERESFLKTFCRQASNSNMRDDSASKKRNSIATG-----AAASSHMTGSRKNALLAALKTIDDNKSQD---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . : * . : : :. ..:. . . :: . : :*::*** *: . ::* ::: : . :* :**: *: *: **..** ::: : *:.:*: * * : : *: * :: * ::: : : . :: .:: . ::* **:.* .** . : :*::.:. :* : ::::*.: .:::** *::: :. : : : *:. ::*: .: :::: *. :. : . . *.:: : : :: . . . :. . . :. : * . . : : : * . : *. * : : : . : . . . . : :. . . :: * : . .. *: : . : .:.:.. :.: . :.: :. . . :. : : : : : .. : * :.::: .: ", "identical_positions": 46, "similar_positions": 196, "identity": "5.69%" }, { "cls_id": "homologset.agr.RGD:1308556", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5PQL3-1", "uniprot_id": "SPP2B_RAT", "id": "Q5PQL3-1", "name": "Signal peptide peptidase-like 2B", "aln": "------MAAARLAASLLLLAAQVACEFGVLRVVPQSGGTRGRDYCILYNPQWAHLPHDLNKVSLLKLRDLSTTQLCSHLDVPVEDFTNQIALVARGNCTFYEKVRLAQGSGAHGLLIVSKERLVPPRGNKTQYEEISIPVALLSHRDLQDIFRRFGHEVMVALYAPSEPVMDYNMVIIFIMAVGTVALGGYWAGSHDVKK-YMKHKRDDVPEKQEDEAVDVTPVMICVFVVMCCFMLVLLYYFYDRLVYVIIGIFCLASSTGLYSCLAPCVRKLPFCTCRVPDNNLPYFHKRPQARMLLLALFCVTVSVVWGVFRNEDQWAWVLQDTLGIAFCLYMLRTIRLPTFKACTLLLLVLFVYDIFFVFITPYLTKSGNSIMVEVATGPSNSSTHEKLPMVLKVPRLNTSPLSLCDRPFSLLGFGDILVPGLLVAYCHRFDIQVQSSRIYFVACTIAYGLGLLVTFVALVLMRHGQPALLYLVPCTLLTSCTVALWRREMGAFWTGSGFA-DAPQTPWAAP--QGPVPPKDVDASLSEQPRGEELAQSPLATEEAGATDPAKDPDS--PVAGPLSPSNG---DQVQPIPVVTPGTSA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TD49-1", "uniprot_id": "SPP2B_MOUSE", "id": "Q3TD49-1", "name": "Signal peptide peptidase-like 2B", "aln": "------MAAARLAAALLLLAAQVACEFGVLRVVSQTSRTRSRDYCILYNPQWAHLPHDLSKVSLLKLRDLSTTQLCSYLDVPAEDFTNQIALVARGNCTFYEKVRLAQGSGAHGLLIVSKEKLVPPGGNKTQYEEISIPVALLSHRDLQDIFRRFGREVMVALYAPSEPVMDYNMVIIFVMAVGTVAIGGYWAGSHDVKK-YMKHKRDDGPEKQEDEAVDVTPVMICVFVVMCCFMLVLLYYFYDRLVYVIIGIFCLASSTGLYSCLAPFVRKLPFCTCRVPDNNLPYFHKRPQARMLLLALFCVTVSVVWGIFRNEDQWAWVLQDTLGIAFCLYMLKTIRLPTFKACTLLLLVLFIYDIFFVFITPFLTKSGNSIMVEVATGPSNSSTHEKLPMVLKVPRLNTSPLSLCDRPFSLLGFGDILVPGLLVAYCHRFDIQVQSSRIYFVACTIAYGLGLLVTFVALVLMQRGQPALLYLVPCTLLTSCTVALWRRELGAFWTGSGFAKDAPQTPWAAT--QGPVPPKAVGSSLSEQPPSEELAKSPLSTEEAGAADPAKDPDN--PVASPLSPSNG---DEAQPIPVVKPETSA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TCT7-1", "uniprot_id": "SPP2B_HUMAN", "id": "Q8TCT7-1", "name": "Signal peptide peptidase-like 2B", "aln": "MAAAVAAALARLLAAFLLLAAQVACEYGMVHVVSQAGGPEGKDYCILYNPQWAHLPHDLSKASFLQLRNWTASLLCSAADLPARGFSNQIPLVARGNCTFYEKVRLAQGSGARGLLIVSRERLVPPGGNKTQYDEIGIPVALLSYKDMLDIFTRFGRTVRAALYAPKEPVLDYNMVIIFIMAVGTVAIGGYWAGSRDVKKRYMKHKRDDGPEKQEDEAVDVTPVMTCVFVVMCCSMLVLLYYFYDLLVYVVIGIFCLASATGLYSCLAPCVRRLPFGKCRIPNNSLPYFHKRPQARMLLLALFCVAVSVVWGVFRNEDQWAWVLQDALGIAFCLYMLKTIRLPTFKACTLLLLVLFLYDIFFVFITPFLTKSGSSIMVEVATGPSDSATREKLPMVLKVPRLNSSPLALCDRPFSLLGFGDILVPGLLVAYCHRFDIQVQSSRVYFVACTIAYGVGLLVTFVALALMQRGQPALLYLVPCTLVTSCAVALWRRELGVFWTGSGFAKVLPPSPWAPAPADGPQPPKDSATPLSPQPPSEEPATSPWPAEQSPKSRTSEEMGAGAPMREPGSPAESEGRDQAQPSPVTQPGASA", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *** *::**********:*:::**.*:. ...:*****************.*.*:*:**: ::: *** *:*...*:***.*********************:******:*:**** ******:**.*******::*: *** ***: * .*****.***:********:*******:*******:**** ******** *************** ******** ********** ****:********:********* **:*** .**:*:*.********************:******:*************:**********:******************:**********:*****.***********:*:*:*************:***:***********************************:**********:*********.**::*************:***:*******:*.******** * :***.. :** *** :.** ** .** * ** .:*:: : .::: . *: * **::. *:.** **. * :**", "identical_positions": 440, "similar_positions": 95, "identity": "74.32%" }, { "cls_id": "homologset.agr.RGD:1308557", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q0KL01-1", "uniprot_id": "UBX2B_MOUSE", "id": "Q0KL01-1", "name": "UBX domain-containing protein 2B", "aln": "--------------------------MAEGGRAEPEEQERGSSRPRPPSARDLQLALAELYEDEMKCKSSKPD----------------------------RSTPATCRSPRTPPHRLYSGDH-----------------------------KYDGLHIVQPP-TGKIVNELFKEAREHGAVPLNEATRSSREDKT--KSFTGGGYRLGNSFYKRSEYIYG-----ENQLQDVQVLLKLWRNGFSLDDGELRPYSDPTNAQFLESVKRGETPLELQRLVHGAQVNLDMEDHQDQEYIKPRLRFKAFSGEGQKLGSLTPEIVSTPSSPEEEDKSILNAAVLIDDSMP-TTKIQIRLADGSRLVQRFNSTHRILDVRDFIVRSRPEFATTDFILVTSFPSKELTDETVTLQEADILNTVILQQLK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0C627-1", "uniprot_id": "UBX2B_RAT", "id": "P0C627-1", "name": "UBX domain-containing protein 2B", "aln": "--------------------------MAEGGGAEPEEQERRSSRPRPPSARDLQLALAELYEDEMKCKSSKPD----------------------------RSTATAFKSPRTPPLRLYSGDQ-----------------------------EYGGLHIAQPP-TGKIVNELFKEAREHGAVPLNEATRSSSDDKA--KSFTGGGYRLGSSFYKRSEYIYG-----ENQLQDVQILLRLWSNGFSLDDGELRPYSDPTNAQFLESVKRGEIPLELQRLVHGSQVSLDMEDHQDQEYIKPRLRFKAFSGEGQKLGSLTPEIVSTPSSPEEEDKSILNAAVLIDDSVP-TTKIQIRLADGSRLIQRFNSTHRILDVRDFIVQSRPEFATTDFILVTSFPSKELTDESVTLQDADILNTVILQQLK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14CS0-1", "uniprot_id": "UBX2B_HUMAN", "id": "Q14CS0-1", "name": "UBX domain-containing protein 2B", "aln": "--------------------------MAEGGGPEPGEQERRSSGPRPPSARDLQLALAELYEDEVKCKSSKSN----------------------------RPKATVFKSPRTPPQRFYSSEH-----------------------------EYSGLNIVRPS-TGKIVNELFKEAREHGAVPLNEATRASGDDKS--KSFTGGGYRLGSSFCKRSEYIYG-----ENQLQDVQILLKLWSNGFSLDDGELRPYNEPTNAQFLESVKRGEIPLELQRLVHGGQVNLDMEDHQDQEYIKPRLRFKAFSGEGQKLGSLTPEIVSTPSSPEEEDKSILNAVVLIDDSVP-TTKIQIRLADGSRLIQRFNSTHRILDVRNFIVQSRPEFAALDFILVTSFPNKELTDESLTLLEADILNTVLLQQLK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P34223-1", "uniprot_id": "UBX1_YEAST", "id": "P34223-1", "name": "UBX domain-containing protein 1", "aln": "MAEIPDETIQQFMALTNVSHNIAVQYLSEFGDLNEALNSYYASQTDDQKDRREEAHWNRQQEKALKQEAFSTNSSNKAINTEHVGGLCPKPGSSQGSNEYLKRKGSTSPEPTKGSSRSGSGNNSRFMSFSDMVRGQADDDDEDQPRNTFAGGETSGLEVTDPSDPNSLLKDLLEKARRGGQMGAENGFRDDEDHEMGANRFTGRGFRLGSTIDAADEVVEDNTSQSQRRPEKVTREITFWKEGFQVADGPLYRYDDPANSFYLSELNQGRAPLKLLDVQFGQEVEVNVYKKLDESYKAPTRKLGGFSGQGQRLGSPIPGESSPAEVPKNETPAAQEQPMPDNEPKQGDTSIQIRYANGKREVLHCNSTDTVKFLYEHVTSNANTDPSRNFTLNYAFPIKPISNDETTLKDADLLNSVVVQRWA", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::* * : :. :* . . * : . *. :* :: ..: : . :. .* . . * *.:: : .**.:. *. ...::::*:::**. * : ::. * . :.: : *** *:***.:: .* : . :.: :.* : :* :**.: ** * *.:*:*: :*..:::*. **:* : .* :*.::: .: *:.* * :: .***:**:*** * *... *::* : : : ::. *.**** *:*.* : : ***. : : :.:. . .: :* * :** * :::: ** :**:**:*::*: ", "identical_positions": 81, "similar_positions": 136, "identity": "19.15%" }, { "cls_id": "homologset.agr.RGD:1308558", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K1D2-1", "uniprot_id": "A0A0G2K1D2_RAT", "id": "A0A0G2K1D2-1", "name": "Rap1 GTPase-GDP dissociation stimulator 1", "aln": "--MDNLSDALKKLKITAADKTEGSLEGCLDCLLQALAQNNAETSEKIQGSGILQLFANLLTPQASCTAKVANIIAEVAKNEFMRIPCVDAGLISPLVQLLNSK-----DQEVLLQTGRALGNICYDSHEGRSAVDQAGGAQIVIDHLRSLCGRADPAN--------EKLLTVFCGMLMNYSNENDSLQAQLINMGVIPTLVKLLGIHCHNAALTEMCLVAFGNLAELESS--KEQFASTNIAEELVKLFKKQIEHDKREMIFEVLAPLAENDAIKLQLVEAGLVECLLEIVQQ-KVDSTKEDDLAELKTASDLMVLLLLGDESMQKLFEGGKGSVFQRVLSWIPSNSQQLQLAGALAIANFARNDGNCIHMVDNGIVEKLMDLLDR-HVEDGNVTVQHAALSALRNLAIPVVNKAKMLSAGVTETVLKFLKSEMPPVQFK-LLGTLRMLIDAQAEAAEQLGKNAKLVERLVEWCEAKDHAG-VMGESNRLLSALIRHSKSKDVIKTIVQ------------------------------SGGIKHLVTMATSEHVIMQNEALVALALIAALELGPAEKDLASAQLVQILHRLLADERSAPEIKYNSMVLICALMGSEALHKEVQDLAFLD-VVSKLRSHENKS------------------VAQQASLTEQRLTVQS------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q912-1", "uniprot_id": "GDS1_MOUSE", "id": "E9Q912-1", "name": "Rap1 GTPase-GDP dissociation stimulator 1", "aln": "--MDNLSDTLKKLKITAADRTEGSLEGCLDCLLQALAQNNAETSEKIQGSGILQLFANLLTPQASCTAKVADIIAEVAKNEFMRIPCVDAGLISPLVQLLNSK-----DQEVLLQTGRALGNICYDSHEGRSAVDQAGGAQIVIDHLRSLCGRTDPAS--------EKLMTVFCGMLMNYSNENDSLQAQLISMGVIPTLVKLLGIHCHNAALTEMCLVAFGNLAELESS--KEQFASTNIAEELVKLFKKQIEHDKREMIFEVLAPLAENDAIKLQLVEAGLVECLLEIVQQ-KVDSNKEDDVAELKTASDLMVLLLLGDESMQKLFEGGKGSVFQRVLSWIPSNNHQLQLAGALAIANFARNDGNCIHMVDNGIVEKLMDLLDR-HVEDGNVTVQHAALSALRNLAIPVVNKAKMLSAGVTETVLKFLKSEMPPVQFK-LLGTLRMLIDAQAEAAEQLGKNAKLVERLVEWCEAKDHAG-VMGESNRLLSALIRHSKSKDVIKTIVQ------------------------------SGGIKHLVTMATSEHVIMQNEALVALALIAALELGPAEKDLASAQLVQILHRLLADERSAPEIKYNSMVLICALMGSESLYKEVQDLAFLD-VVSKLRSHENKS------------------VAQQASLTEQRLTVES------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P52306-1", "uniprot_id": "GDS1_HUMAN", "id": "P52306-1", "name": "Rap1 GTPase-GDP dissociation stimulator 1", "aln": "--MDNLSDTLKKLKITAVDKTEDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFASLLTPQSSCKAKVANIIAEVAKNEFMRIPCVDAGLISPLVQLLNSK-----DQEVLLQTGRALGNICYDSHEGRSAVDQAGGAQIVIDHLRSLCSITDPAN--------EKLLTVFCGMLMNYSNENDSLQAQLINMGVIPTLVKLLGIHCQNAALTEMCLVAFGNLAELESS--KEQFASTNIAEELVKLFKKQIEHDKREMIFEVLAPLAENDAIKLQLVEAGLVECLLEIVQQ-KVDSDKEDDITELKTGSDLMVLLLLGDESMQKLFEGGKGSVFQRVLSWIPSNNHQLQLAGALAIANFARNDANCIHMVDNGIVEKLMDLLDR-HVEDGNVTVQHAALSALRNLAIPVINKAKMLSAGVTEAVLKFLKSEMPPVQFK-LLGTLRMLIDAQAEAAEQLGKNVKLVERLVEWCEAKDHAG-VMGESNRLLSALIRHSKSKDVIKTIVQ------------------------------SGGIKHLVTMATSEHVIMQNEALVALALIAALELGTAEKDLESAKLVQILHRLLADERSAPEIKYNSMVLICALMGSECLHKEVQDLAFLD-VVSKLRSHENKS------------------VAQQASLTEQRLTVES------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1Z6S7-1", "uniprot_id": "GDS1_DROME", "id": "A1Z6S7-1", "name": "GTPase-GDP dissociation stimulator vimar", "aln": "MATAEIDDLIEKLKTTSVSPAN-----TTNLLCEISATKDPKLFDKHELAECFLGLT--KCDDTNVRKEAAKCIAEITKSEVQRKKFTKRNIIAAFLECLRQVPTSDGSMELPIQICRALGNICYLNDEARDLILELEGDAVLLRLLDITTIEDVANA--------AQFIKVRGGLLSNYLLGGEGLAKRAMELGVMKKLQGIIDIGASNVEQHEDLLLNTLPLLSILTENVSDLNFDSSLNIQLSRILAASTNPDLAEMCLELLHYQAESDEVKLILAKDGLCETIYNLLEKYKTLASTSEARALMKLACELIVLILTGDDSMHYLYTTP---LLKNMVDWLDSTDIDLLTTGVLALGNFARTDSHCIYFVEQQTMNKLLEVLAKNNGVKDDVRLQHALLSALRNLVIPKPNKNAVIQAGLVQTILPMLEIHQPPVVFK-LLGTLRMTVDGQEKLALELLKNKTLIEQLVHWSKSSDYAG-VTGESLRLMAWLIKHAYLSKIAYALPRKGDAPAEQIADKIPLTQDYDRSSLSEFLANEGTVEAMVSMLTAQHLVMQNEALIALCILSVVYLSQPSEAAQAQLLQDELVKCEVGKKLAELISKSSDTMTKEIVEN--LQNCVNLLKSSEQLVAHLEQHNINE------------------LLKSIPILTEYCTL--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39011-1", "uniprot_id": "GDS1_YEAST", "id": "P39011-1", "name": "GTPase-GDP dissociation stimulator BEM4", "aln": "---MDYEEILFGLQP----------------ILNASSIKDVPMNDVYLGSYLAVMDQLAVSLREPSNRDIVGKTGLLLNLVRVLEQALDICFHDTSISINDKIA----FYEISSEVIRCIANAIIDNDDNREILLDSGGKKLLNYYIGGVLQLDEISSDKSEDSLVDKLQMRSVVLLRNFCIGNLKYTENLAPFIRGPLFVLLKTTQYSYLSSPEKVVLGSDLLNDILKVNYSNVQISDLFFLSQYIKKISSNVQNKELQAMEDGAVEAYSNTETQKFAGQGNQEYIEKEEED----DEEDVNCELLLNLSTCLETIVAKDETINFTNEEQLVLSMQKNLILSLVCLESKTFNNKLIVMRRLISCAGNISANLTNSNKREQSLCIETIKSSASSYALAAALMILCNSVASKSDAVALLKLISLSELIQVGSLLQDPLQYQGFLDLLRKLLNLENTMWLDIKDLFTLFQIMRRCHEQTKYYNNLRSLLTNLLNKTLTVLPSSKIHNSISSD-----------------------PTIISFIAEHGTLTSCIAMDKLLVSKKALPKEAITSLWDSIFKFQNLGQAEQLSISDLFHITKTVGIYLKDSSVTADVNPIENILFKDYIQKLTLILETILSFKENKDKGSESCFNNGKFIAGIILNIVKNTKCLTPEEQNLEALAKSFF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .: : *: : : : :: : : . . . : : . : . :. . *: : *.:.* ..: *. : : * :: : :: :* *: . . : : : * :: * .: . .: . : . . : :* * .: . :. * * : : :. . : . : :: *:::: ::. : . . * : . . . * :: .: . . . * * * * . . : ::. . :: . . *: :: :*. ** :: : :: . .*.: : . : ..: . : . .*: : ..: :: . :.: : :::::.::** .: : : . : . :. .* . : . : . :: * : :..:: : : : : : .: ", "identical_positions": 31, "similar_positions": 180, "identity": "4.54%" }, { "cls_id": "homologset.agr.RGD:1308559", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZP60-1", "uniprot_id": "D3ZP60_RAT", "id": "D3ZP60-1", "name": "", "aln": "MPGLLNCFTGAALPLTASDVTSYVSGYALGLTASLTYGNLEAQPFQGLFVYPTDECTTVVGFEAVIADRVVTIQLRDKAKLDRSYLD---VQSATVTGNLPEEEIPITP-----GKVTLDEDLERILFVVNLGTIAPMENVTIFISTSSELPTLPSGAVRVLLPAICAPTVHPFCAHRFGSSRQQPRGKDPHCFGTQSKDSYKRLCLATLLDTKVTNPMEYEFKFQLEIRGPCLLAGVESPTHEIRADAAPSAHSAKSIIITLAKKHTFDRPVEILLHPSEPHMPHVLVEKGDMTLGEFYQHLKRKADFVRGTKKDNIAERKTEVIRKRLHKDIPHHSVIMLNFCPDLESVQPNPRRTHGEFIFLIDRSSSMSKTNIQCIKEAMLVALKSLMPACLFNVIGFGSTFKTVFASSQIYNEENLALACECIQRMRADMGGTNIFSPLKWVLRQPLRQGHPRLLFLITDGSVNNTGKVLELVRNHASSIRCYSFGIGPTVCYRLVKGLASVSKGSAEFLMEGERLQPKMVKSLKKAMAPVLSDVTVEWVFPETTEALISPVSTSSLFPGERLVGYGIVCDASLYISNSRSDKRRKYGMLHAQESSSSVFYHSQDEGLRPGSGNCAKN----FNQGQTKDAHPCNGDSLSHHGLDGSRRRRAYSTNQISSHKACSRATTASDPTGTTRRYPLRKAKVQDLAHQSSSESQQWQIDLQPLLTRGHDPSQGPRLHGPGARRPSLLPQGCQPMRFSGPEPQAWSPVRELGLGSGRKSVLNSRSSEDLATEPPPFPSTLEPETSSDLEPTAELEEQA-PYRTATPSPVLGKVLVKGVCDNQHMQWEVSFELEPPALRREDTQNDDMWGETFHHLAARAIIREFEHLAQREDEIELGSNRRYQVNAVHTSKACNVISKYTAFVPVDINKRQYLPTVVKYHNSGAL--LSFRNLTRQWKGFSTGLRRSQSMLREHSSAAGDSKFQTLALHESLTSTFNKTPSPGHEKYATAEGPPQNLSTSSLSSTKASEAIFGSRLILNKSRLLTRATKNFLSKSLPKAPEVNPGSQSSDYVPLVSLQLASGAFLLNEVFCRTIQIPMEKLKWTSPFNCLRMSLVTRRHDLKTQSPGDCTSLSSPPPPSDDISLKSGAKDSSDQESSELLEHTGKLWATVVALAWLEHSSASYIIEWELVAAKASSWVELQEVPEGRTLSTIKATARQLFVLLRHWDENLEFNMLCYNPNYM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A9Z1V5-1", "uniprot_id": "VW5B1_MOUSE", "id": "A9Z1V5-1", "name": "von Willebrand factor A domain-containing protein 5B1", "aln": "MPGLLNCLTGAALPLMESDVTSYVSGYALGLTASLTYGNLEAQPFQGLFVYPIDEYSTVVGFEAVIADRVVTIQLRDKAKLDRSHLD---IQPATVTGNFPEEESPIAP-----GKVTLDEDLERVLFVVNLGTIAPMENVTVFISTSSELPTLPSGAVRVLLPAICAPTVPPSCTHRFGSSSPQPQGKDPHCFGTQTKDSYNRLCLATLLDTKVTNPMEYEFKFQLEIRGPCLLAGVESPTHEIRADAAPSAHSAKSIIITLAKKHTFDRPVEILLHPSEPHMPHVLVEKGDMTLGEYDQHLKGKADFIRGTKKDNSAERKTEVIRKRLHKDIPHHSVIMLNFCPDLQSVQPNPRKAHGEFIFLIDRSNSMSKTNIQCIKEAMLVALKSLMPACFFNIIGFGSTFKAVFASSRIYNEENLTMACDCIQRMQADMGGTNMLSPLKWVLRQPLRRGHPRLLFLITDGSVNNTGKVLELVRNHASSTRCYSFGIGPTVCYRLVKGLASVSKGSAEFLMEGERLQPKMVKSLKKAMAPVLSDVTVEWVFPETTEALISPVSTSSLFPGERLMGYGIVCDASLYISNSRSDKRRKYGMLHTQESSSSVFYPSQDEGLSPGSGNCAKN----VNQGQTKDAHPCNGDSPTHHGLDVSRRRRAYSTNQISSHKTCPRATTASDPTGTARRYPLRKAKVQDLASESDWESQKWQTDLQTLLNEGHNLSQGPKLHGPGARRPSLLPQGCQLMRFFDQKPQAWGPVRELDCGASRTSAPNSQSSEDLAIEPAHCPSTFERETSLDLEPMAESEEQANPCRTATPSPVVGKALVKGLCANQRMQWEVSFELEPPALKRGDTQNADMWSETFHHLAARAIIREFEHLAEREDEIELGSNRRYQVNAVHTSKACSVISKYTAFVPVDINKRQYLPTVVKYPNSGAM--LSFRNLTRQWGGSSAGLGRPQSMLREHSSAAGDSKFQTLALQDSPTSTFNKTPSPGHEKQTTAEGPPQNLSASAPSSMKATETLFGSKLNLNKSRLLTRATKGFLSKSLPKASEATPGSQSSDYIPLVSLQLASGAFLLNEAFCTTIQIPMEKLKWTSPFSCLRMSLVTRRQDLKTQSPQDCTSLSSSPPSCDGISLKS--EESSDQESNAMLEHMGKLWATVVALAWLEHSSANYIIEWELVAAKASSWVEKQKVPEGRTLSTLKNTARQLFVLLRHWDEKLEFNMLCYNPNYV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5TIE3-1", "uniprot_id": "VW5B1_HUMAN", "id": "Q5TIE3-1", "name": "von Willebrand factor A domain-containing protein 5B1", "aln": "MPGLLNWITGAALPLTASDVTSCVSGYALGLTASLTYGNLEAQPFQGLFVYPLDECTTVIGFEAVIADRVVTVQIKDKAKLESGHFDASHVRSPTVTGNILQDGVSIAPHSCTPGKVTLDEDLERILFVANLGTIAPMENVTIFISTSSELPTLPSGAVRVLLPAVCAPTVPQFCTKSTGTSNQQAQGKDRHCFGAWAPGSWNKLCLATLLNTEVSNPMEYEFNFQLEIRGPCLLAGVESPTHEIRADAAPSARSAKSIIITLANKHTFDRPVEILIHPSEPHMPHVLIEKGDMTLGEFDQHLKGRTDFIKGMKKKSRAERKTEIIRKRLHKDIPHHSVIMLNFCPDLQSVQPCLRKAHGEFIFLIDRSSSMSGISMHRVKDAMLVALKSLMPACLFNIIGFGSTFKSLFPSSQTYSEDSLAMACDDIQRMKADMGGTNILSPLKWVIRQPVHRGHPRLLFVITDGAVNNTGKVLELVRNHAFSTRCYSFGIGPNVCHRLVKGLASVSEGSAELLMEGERLQPKMVKSLKKAMAPVLSDVTVEWIFPETTEVLVSPVSASSLFPGERLVGYGIVCDASLHISNPRSDKRRRYSMLHSQESGSSVFYHSQDDGPGLEGGDCAKNSGAPFILGQAKNARLASGDSTTKHDLNLSQRRRAYSTNQITNHKPLPRATMASDPMPAAKRYPLRKARLQDLTNQTSLDVQRWQIDLQPLLNSGQDLNQGPKLRGPGARRPSLLPQGCQPFLPWGQETQAWSPVRER--------TSDSRSPGDL--EPSHHPSAFETETSSDWDPPAESQERASPSRPATPAPVLGKALVKGLHDSQRLQWEVSFELGTPGPERGGAQDADLWSETFHHLAARAIIRDFEQLAEREGEIEQGSNRRYQVSALHTSKACNIISKYTAFVPVDVSKSRYLPTVVEYPNSAALRMLGSRALAQQWRGTSSGFGRPQTMLGEDS-APGNGKFQALNMEASPTALFSEARSPGREKHGASEGPQRSLATNTLSSMKASENLFGSWLNLNKSRLLTRAAKGFLSKPLIKAVESTSGNQSFDYIPLVSLQLASGAFLLNEAFCEATHIPMEKLKWTSPFTCHRVSLTTRPSESKTPSPQLCTSSPPRHPSCDSFSLEPLAKGKLGLEPRAVVEHTGKLWATVVGLAWLEHSSASYFTEWELVAAKANSWLEQQEVPEGRTQGTLKAAARQLFVLLRHWDENLEFNMLCYNPNYV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****** :******* ***** ***************************** ** :**:************:*::*****: .::* ::..*****: :: .*:* ***********:***.************:**********************:***** *:: *:* *.:*** ****: : .*:::*******:*:*:*******:*****************************:**********:***********:***********:*********: **** ::**::* **.. ******:***********************:**** *::***********.*** .:: :*:*************:**:********::*.**: *.*:.*::**: ****:*******::******:***:::*******:****:*************** * *********.**:**********:****:******************************:******.*:****:*********:**********:***.******:*.***:***.***** ***:* .*:**** . **:*:*: ..*** ::*.*: *:**********:.**. .*** **** :::*******::***: ::. : *:** ***.**. *:: .***:*:*************** : . :.***.**** . :*:*. ** **. **::* *** * :* ** :*:* * *.***:**:**.****: .*::******** .*. .* .:*: *:*.*************:**:**:**.*** ********.*:******.:***********:.* :******:* **.*: *. * *::** * *:*: *.*:** *.* *.*:.***:* :. * *: *.:: ***:** ::*** :.*::.: ** **:* :*** * **********:*.****.* ** * ..*.** **:****************.** : :************.* *:**.** : ** ** *** .. *..*.:**:. : . . *. ::** ********.*********.*: *********.**:* *:****** .*:* :*************:************:", "identical_positions": 836, "similar_positions": 244, "identity": "67.91%" }, { "cls_id": "homologset.agr.RGD:1308560", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6APQ3-1", "uniprot_id": "A0A8I6APQ3_RAT", "id": "A0A8I6APQ3-1", "name": "", "aln": "MGGVRQKQPAASGCSPLALSSAPEPLRLRKVRGGELACAIGAGPEEADRGRAPEGRLRTALTRVPLSHYPAVSAHLLESSSCRRPGETPPLVELSNYRILAHCWVSWTADLLSQEKMGKGCKVVVCGLLSVGKTAILEQLLYGNHTIGMEDCETLEDVYMASVETDRG-VKEQLHLYDTRGLQ-EGVELPKHYFSFADGFVLVYSVNNLESFQRVELLKKEIDKFKDKKEVAIVVLGNKLDLSEQRQVD--ADAAQQWARSEKVKLWEVTVTDRRTLIEPFTLLASKLSQPQSKSSFPLPGRKNKGNSNSEN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CEC5-1", "uniprot_id": "KBRS1_MOUSE", "id": "Q8CEC5-1", "name": "NF-kappa-B inhibitor-interacting Ras-like protein 1", "aln": "--------------------------------------------------------------------------------------------------------------------MGKGCKVVICGLLSVGKTAILEQLLYGNHTIGMEDCETLEDVYMASVETDRG-VKEQLHLYDTRGLQ-KGVELPKHYFSFADGFVLVYSVNNLESFQRVELLKKEIDKFKDKKEVAIVVLGNKLDLSEQRQVD--ADVAQQWARSEKVKLWEVTVTDRRTLIEPFTLLASKLSQPQSKSSFPLPGRKNKGNSNPEN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NYS0-1", "uniprot_id": "KBRS1_HUMAN", "id": "Q9NYS0-1", "name": "NF-kappa-B inhibitor-interacting Ras-like protein 1", "aln": "--------------------------------------------------------------------------------------------------------------------MGKGCKVVVCGLLSVGKTAILEQLLYGNHTIGMEDCETMEDVYMASVETDRG-VKEQLHLYDTRGLQ-EGVELPKHYFSFADGFVLVYSVNNLESFQRVELLKKEIDKFKDKKEVAIVVLGNKIDLSEQRQVD--AEVAQQWAKSEKVRLWEVTVTDRKTLIEPFTLLASKLSQPQSKSSFPLPGRKNKGNSNSEN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DGQ1-1", "uniprot_id": "KBRS1_DANRE", "id": "Q6DGQ1-1", "name": "NF-kappa-B inhibitor-interacting Ras-like protein 1", "aln": "--------------------------------------------------------------------------------------------------------------------MGKGCKVVVCGMASVGKTAILEQLLYGSHTVGAETSDTQEDIYVASVETDRG-VREQLRLYDTRGLR-EGLDLPKHFFSVADGFVLVYSVDCLESFKKVEVLKKEIDRSRDKKEVMVMVLGNKCELRERRQVD--QDTAQQWARGEKVKLWEVTVTDRSTLIEPFTSLTSRLTQPQSKSAFPLPGRKSKGTPSNDI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V4L4-1", "uniprot_id": "KBRAS_DROME", "id": "Q9V4L4-1", "name": "NF-kappa-B inhibitor-interacting Ras-like protein", "aln": "---------------------------------------------------------------------------------------------------------------MLNAKIGKVGKVLVCGMKGVGKTALIEQLVYGHVNPETELHPTIEDIYVASVDTGRGGARETLRIYDTAGLQGEQQQLPRHYLQFPDAFVLVYDPMDPRSLDMLADIKADIEKHKEKKEIPVVVLANVRARAAPNPVEKVMDRANIWCQRERIKHYTVNAMERPSLYEPFTTLCARLHPMQTKSTFPQLRQVMQNRQKSEA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :** **::**: .*****::***:** . * * **:*:***:*.** .:* *::*** **: : :**:*::...*.*****. .*:. : :* :*:: ::***: ::**.* . *: : *: *.: *::: : *.. :* :* **** * ::* *:**:** : :. . : ", "identical_positions": 70, "similar_positions": 65, "identity": "22.44%" }, { "cls_id": "homologset.agr.RGD:1308561", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9HCK0-1", "uniprot_id": "ZBT26_HUMAN", "id": "Q9HCK0-1", "name": "Zinc finger and BTB domain-containing protein 26", "aln": "MSERSDLLHFKFENYGDSMLQKMNKLREENKFCDVTVLIDDIEVQGHKIVFAAGSPFLRDQFLLNDSREVKISILQSSEVGRQLLLSCYSGVLEFPEMELVNYLTAASFLQMSHIVERCTQALWKFIKPKQPMDSKEGCEPQSASPQSKEQQGDARGSPKQDSPCIHPSEDSMDMEDSDIQIVKVESIGDVSEVRSKKDQNQFISSEPTALHSSEPQHSLINSTVENRVSEIEQNHLHNYALSYTGSDNIIMASKDVFGPNIRGVDKGLQWHHQCPKCTRVFRHLENYANHLKMHKLFMCLLCGKTFTQKGNLHRHMRVHAGIKPFQCKICGKTFSQKCSLQDHLNLHSGDKPHKCNYCDMVFAHKPVLRKHLKQLHGKNSFDNANERNVQDLTVDFDSFACTTVTDSKGCQPQPDATQVLDAGKLAQAVLNLRNDSTCVN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0L735-1", "uniprot_id": "A0ABK0L735_RAT", "id": "A0ABK0L735-1", "name": "", "aln": "MSERSDLLHFKFENYGDSMLQKMNKLREENKFCDVTVLIDDVEVQGHKIVFAAGSPFLRDQFLLNDSREVKISILQSSEVGRQLLLSCYSGVLEFPEMELVNYLTAASFLQMSHIVERCTQALWKFIKPKQPMDSKEGSEPQSASPQSKEQQGDARGSPKQDLPCIHPSEDSMDMEDSDIQIVKVESIGDVSEDRSKKDQNQYISSEPTALHSSEPQHSLINSTVENRVNELDQSHLHNYALSYTGNDDIIMTSKDVFGPNIRGVDKGLQWHHQCPKCTRVFRHLENYANHLKMHKLFMCLLCGKTFTQKGNLHRHMRVHAGIKPFQCKICGKTFSQKCSLQDHLNLHSGDKPHKCNYCDMVFAHKPVLRKHLKQLHGKNSFDNANERSVQDLTVDFDSFACTTVTDSN-CQPQPDATQVLDAGKLTQAVLSLRSDSTCVN", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****************************************:************************************************************************************************.*********************** ****************************** ********:**************************.*::*.***********.*:***:***************************************************************************************************************************************.*******************: ****************:****.**.******", "identical_positions": 423, "similar_positions": 15, "identity": "95.92%" }, { "cls_id": "homologset.agr.RGD:1308562", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5BK58-1", "uniprot_id": "Q5BK58_RAT", "id": "Q5BK58-1", "name": "", "aln": "-----MNFTEANYGMEDY---TGSD-YSMFPETEPCSLQEVRDFTKVFVPIAYSLICVFGLLGNIMVVITFAFYKKARSMTDVYLLNMAITDILFVLTLPFWAVTHATDTWIFGNTMCKLMKGTYAVNFNCGMLLLACISMDRYIAIVQATKSFRVRSRTLTHSKVICLTVWFVSIIISSPTFFFNKQYKLQGRDVCEPQYKLVSEPITWKLLGMGLELLFGFFIPLLFMVFCYLFIIKTLVQAQNSKRHRAIRVVIAVVLVFLACQIPHNMVLLVTAANTGKMGRSCSAEKALAYARNVAEVLAFLHCCLNPVLYAFIGQKFRSYFMKIMKDVWCMRRKSKVPTFFCARVYSESYISRQTSETVENDNASSFTM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54689-1", "uniprot_id": "CCR6_MOUSE", "id": "O54689-1", "name": "C-C chemokine receptor type 6", "aln": "-----MNSTESYFGTDDY---DNTEYYSIPPDHGPCSLEEVRNFTKVFVPIAYSLICVFGLLGNIMVVMTFAFYKKARSMTDVYLLNMAITDILFVLTLPFWAVTHATNTWVFSDALCKLMKGTYAVNFNCGMLLLACISMDRYIAIVQATKSFRVRSRTLTHSKVICVAVWFISIIISSPTFIFNKKYELQDRDVCEPRYRSVSEPITWKLLGMGLELFFGFFTPLLFMVFCYLFIIKTLVQAQNSKRHRAIRVVIAVVLVFLACQIPHNMVLLVTAVNTGKVGRSCSTEKVLAYTRNVAEVLAFLHCCLNPVLYAFIGQKFRNYFMKIMKDVWCMRRKNKMPGFLCARVYSESYISRQTSETVENDNASSFTM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P51684-1", "uniprot_id": "CCR6_HUMAN", "id": "P51684-1", "name": "C-C chemokine receptor type 6", "aln": "MSGESMNFSDVFDSSEDYFVSVNTSYYSVDSEMLLCSLQEVRQFSRLFVPIAYSLICVFGLLGNILVVITFAFYKKARSMTDVYLLNMAIADILFVLTLPFWAVSHATGAWVFSNATCKLLKGIYAINFNCGMLLLTCISMDRYIAIVQATKSFRLRSRTLPRSKIICLVVWGLSVIISSSTFVFNQKYNTQGSDVCEPKYQTVSEPIRWKLLMLGLELLFGFFIPLMFMIFCYTFIVKTLVQAQNSKRHKAIRVIIAVVLVFLACQIPHNMVLLVTAANLGKMNRSCQSEKLIGYTKTVTEVLAFLHCCLNPVLYAFIGQKFRNYFLKILKDLWCVRRKYKSSGFSCAGRYSEN-ISRQTSETADNDNASSFTM", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** :: . :** .:. **: .: ***:***:*:::******************:**:*********************:*************:***.:*:*.:: ***:** **:*********:******************:*****.:**:**:.** :*:****.**.**::*: *. *****:*: ***** **** :****:**** **:**:*** **:************:****:**********************.* **:.***.:** :.*::.*:***********************.**:**:**:**:*** * . * ** ***. ********.:*********", "identical_positions": 266, "similar_positions": 71, "identity": "70.93%" }, { "cls_id": "homologset.agr.RGD:1308564", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5SPH3-1", "uniprot_id": "Q5SPH3_MOUSE", "id": "Q5SPH3-1", "name": "Amine oxidase", "aln": "MLPAPGRLLAMFPGWLALIFLSVLSLDTQAFNRKLVKCFEDPQYEELLQLARNGLGQTAERKQVVVIGAGMAGLTAAKILQDAGHQVTVLEASGRVGGRIETHRVPGAHWYIELGAMRIPINHRLSHELIKKFGLMLKEFCPCNNQTWVLVNGVRQRSGAVQADPGLLGYSVRADEVGKTAEQLFDASLRKIVEELKNSSCQEVLEKYDSFSTKEYLIKVGNLSRGAVQMIGDMLNTDSGYYEAFTETLRGIISFFQDPRFDEIVGGFDQLPQALHNSLLPGTVWFYSPAEEVEMSGDCVHVTYRTPDPLLPRARLTADFVVVATTAKAARLLRFQPPLSLNKQDALRSVHYNSATKVILACTQRFWERDGIFSGKSSTDRPSRFIYYPNHIFPNGAGVILASYTLDDDSVFFTALDHTQVVDIVLDDLAALHSRAKEELRALCPYSAIKNWSQDPYSMGGFAFFTPYQYVDYAQELSQPEGLVFFAGEHTDLPHGWIDTAIKSGLRVAKNIQESVDLALTRNPRNTKEYFSKSEL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1LUP3-1", "uniprot_id": "F1LUP3_RAT", "id": "F1LUP3-1", "name": "Amine oxidase", "aln": "MLSVPGRPLAMFPGWLALIFLSVLSLNTQAFNSKLVKCFEDPQYEELLQLARNGLGQTAERKQVVVIGAGMAGLTAAKILQDAGHQVTVLEASGRVGGRIETHRVPGAHWYIELGAMRIPINHRFSHELIKRFGLMLKEFCPCNNQTWVLVNGVRQRSGAVQADPGLLGYSVKADEMGKTAEQLFDASLRKIVEELKNSSCQEVLEKYDSFSTKEYLIKVGNLSRGAVQMIGDMLNTDSGYYEAFTETLRGIISFFQEPRFDEIVGGFDQLPQALHNSLLPGTVWFYSPAEEVERSGDYVHVTYKTPDPLQPRARLTADFVVVATTAKAARLLRFQPPLSLSKQDALRSVHYNSATKVILACKQRFWERDGIFSGKSTTDRPSRFIYYPNHIFPNGAGVILASYTLDDDSVFLTALDHSRVVDIVLDDLAAIHNRPKEELRDLCPYSAIKNWSQDPYSMGGFAFFTPYQYVDYAQELSQPEGPVFFAGEHTDLPHGWIDTAIKSGLRVARNIQESVNLALTRNPRNIKGHFSKSEL", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**..*** ******************:***** *******************************************************************************************:******:****************************************:***:********************************************************************************:************************************ *** *****:***** ******************************.********************.**************:**********************************:*****::***********:*.*.***** **************************************** **************************:******:********* * :******", "identical_positions": 506, "similar_positions": 21, "identity": "94.4%" }, { "cls_id": "homologset.agr.RGD:1308565", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "O15514-1", "uniprot_id": "RPB4_HUMAN", "id": "O15514-1", "name": "DNA-directed RNA polymerase II subunit RPB4", "aln": "-------MAAGGSDPRAGDVEEDASQLIFPKEFETAET------------------------------------LLNSEVHMLLEHRKQQNESAEDEQE-------------------------------------LSEVFMKTLNYTARFSRFKNRETIASVRSLLLQKKLHKFELACLANLCPETAEESKALIPSLEGRFEDEELQQILDDIQTKRSFQY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9D7M8-1", "uniprot_id": "RPB4_MOUSE", "id": "Q9D7M8-1", "name": "DNA-directed RNA polymerase II subunit RPB4", "aln": "-------MAAGGSDPRAGDVEEDASQLIFPKEFETAET------------------------------------LLNSEVHMLLEHRKQQNESAEDEQE-------------------------------------LSEVFMKTLNYTARFSRFKNRETIASVRSLLLQKKLHKFELACLANLCPETAEESKALIPSLEGRFEDEELQQILDDIQTKRSFQY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A259-1", "uniprot_id": "D4A259_RAT", "id": "D4A259-1", "name": "DNA-directed RNA polymerase II subunit RPB4", "aln": "-------MAAGGSDPRAGDVEEDASQLIFPKEFETAET------------------------------------LLNSEVHMLLEHRKQQNESAEDEQE-------------------------------------LSEVFMKTLNYTARFSRFKNRETIASVRSLLLQKKLHKFELACLANLCPETAEESKALIPSLEGRFEDEELQQILDDIQTKRSFQY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M1N062-1", "uniprot_id": "A0A8M1N062_DANRE", "id": "A0A8M1N062-1", "name": "DNA-directed RNA polymerase II subunit RPB4", "aln": "---MNLVMAAAGAT-QVGDVEEDASQLMFPKEFENAET------------------------------------LLNSEVHMLLEHRKQQNESAEDEQE-------------------------------------LSEVFMKTLNYTARFSRFKNRETIASVRSLLLQKKLHKFELASLANLCPEAAEEAKALIPSLEGRFEDEELQQILDDIQTKRSFQY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VEA5-1", "uniprot_id": "RPB4_DROME", "id": "Q9VEA5-1", "name": "DNA-directed RNA polymerase II subunit Rpb4", "aln": "-------MSFMN---PVDMVDEDAADLQFPKEFENAET------------------------------------LLISEVHMLLDHRKRQNESADEEQE-------------------------------------FSEVFMKTYAYTDSFRKFKNKETIMSARSLLMQKKLHKFELAALGNLCPEAPEEAKALIPSLEGRFEDEELRQILDDIGTKRSLQY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P20433-1", "uniprot_id": "RPB4_YEAST", "id": "P20433-1", "name": "DNA-directed RNA polymerase II subunit RPB4", "aln": "MNVSTSTFQTRRRRLKKVEEEENAATLQLGQEFQLKQINHQGEEEELIALNLSEARLVIKEALVERRRAFKRSQKKHKKKHLKHENANDETTAVEDEDDDLDEDDVNADDDDFMHSETREKELESIDVLLEQTTGGNNKDLKNTMQYLTNFSRFRDQETVGAVIQLLKSTGLHPFEVAQLGSLACDTADEAKTLIPSLNNKISDDELERILKELSNLETLY-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :*:*: * : :**: : .: *: :: : :. :.::*:: .: : :* * * :*:::**: :. .** .. ** **:* *..*. ::.:*:*:*****:.::.*:**.:**.:: . .:: ", "identical_positions": 34, "similar_positions": 61, "identity": "15.32%" }, { "cls_id": "homologset.agr.RGD:1308567", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D7H2-1", "uniprot_id": "WDR5B_MOUSE", "id": "Q9D7H2-1", "name": "WD repeat-containing protein 5B", "aln": "-------------------------------MATEHLPAERAQSLLS--APRREEEPQKPNYALRLTLAGHSAAISSVKFSPNGEWLASSAADALIIIWGAYDGNCKKTLYGHSLEISDVAWSSDSSRLVSASDDKTLKVWDMRSGKCLKTLKGHSDFVFCCDFNPPSNLIVSGSFDESVKIWEVKTGKCLKTLSAHSDPISAVNFNCN-GSLIVSGSYDGLCRIWDAASGQCLRTLADEGNP-------PVSFVKFSPNGKYILTATLDNTLKLWDYSRGRCLKTYTGHKNEK-----YCLFASFSVTGR--KWVVSGSEDNMVYIWNLQTKEIVQRLQG----HTDVVISAACHPTKNIIASAALENDKTIKVWSSDC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4V8C4-1", "uniprot_id": "WDR5B_RAT", "id": "Q4V8C4-1", "name": "WD repeat-containing protein 5B", "aln": "-------------------------------MATEHLPAERAQSPLS--APQRVEEPQKPNYALRLTLAGHSAAISSVKFSPNGEWLASSAADALIIIWGAYDGKCKKTLYGHSLEISDVAWSSDSSRLVSASDDKTLKLWDVRSGKCLKTLKGHSDFVFCCDFNPPSNLIVSGSFDESVKIWEVKTGKCLKTLSAHSDPISAVHFHCN-GSLIVSGSYDGLCRIWDAASGQCLRTLADEGNP-------PVSFVKFSPNGKYILTATLDSTLKLWDYSRGRCLKTYTGHKNEK-----YCIFASFSVTGR--KWVVSGSEDNMVYIWNLQTKEIVQRLQG----HTDVVISAACHPTENIIASAALENDKTIKIWSSDY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q86VZ2-1", "uniprot_id": "WDR5B_HUMAN", "id": "Q86VZ2-1", "name": "WD repeat-containing protein 5B", "aln": "-------------------------------MATKESRDAKAQLALSSSANQSKEVPENPNYALKCTLVGHTEAVSSVKFSPNGEWLASSSADRLIIIWGAYDGKYEKTLYGHNLEISDVAWSSDSSRLVSASDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPPSNLIISGSFDETVKIWEVKTGKCLKTLSAHSDPVSAVHFNCS-GSLIVSGSYDGLCRIWDAASGQCLKTLVDDDNP-------PVSFVKFSPNGKYILTATLDNTLKLWDYSRGRCLKTYTGHKNEK-----YCIFANFSVTGG--KWIVSGSEDNLVYIWNLQTKEIVQKLQG----HTDVVISAACHPTENLIASAALENDKTIKLWMSNH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V3J8-1", "uniprot_id": "WDS_DROME", "id": "Q9V3J8-1", "name": "Protein will die slowly", "aln": "MVPIGAVHGGHPGVVHPPQQPLPTAPSGPNSLQPNSVGQPGATTSSNSSASNKSSLSVKPNYTLKFTLAGHTKAVSAVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSRLLVSGSDDKTLKVWELSTGKSLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVRTGKCLKTLPAHSDPVSAVHFNRD-GSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNP-------PVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEK-----YCIFANFSVTGG--KWIVSGSEDNMVYIWNLQSKEVVQKLQG----HTDTVLCTACHPTENIIASAALENDKTIKLWKSDT", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38123-1", "uniprot_id": "SWD3_YEAST", "id": "P38123-1", "name": "COMPASS component SWD3", "aln": "--------------------------------------------------MFQFVTPVGTQNGLKATCA---------KISPDGQFLAITQGLNILIYDINRRTVSQTLVTSHARPFSELCWSPDGQCIATASDDFSVEIIHLSYG-LLHTFIGHTAPVISLTFNRKGNLLFTSSMDESIKIWDTLNGSLMKTISAHSEAVVSVDVPMNDSSILSSGSYDGLIRIFDAETGHCLKTLTYDKDWKRENGVVPISQVKFSENARYLLVKSLDGVVKIWDCIGGCVVRTFQVQPLEKGVLHHSCGMDFLNPEDGSTPLVISGYENGDIYCWNSDTKSLLQLLDGSLYHHSSPVMSIHCFG--NIMCSLALNGDCCLWRWV---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .: *: * . *:**:*::** : . :: :. : .* :*::.**.*. :.:.*** :::: .: * *:*: **: *:. ** .**:.:.*:**:::**:. .*. :**:.***:.: :*.. . .*:: *.***** **:*: :*:**:** : : *:* **** *.:*:*. :**..:*:** * ::*: : ** * : :. . ::** *:. :* ** ::*.::* *:* *:. *:. *. *::.* **:.* : * ", "identical_positions": 91, "similar_positions": 112, "identity": "23.95%" }, { "cls_id": "homologset.agr.RGD:1308568", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZQG2-1", "uniprot_id": "A0A8I5ZQG2_RAT", "id": "A0A8I5ZQG2-1", "name": "Testican-2", "aln": "-MRAPGSGRLALPLLLLAVVALAEGDAKGLK------------------EGETPGNFMEDEQWLSSIS-----------------------------------------------QYSGKIKHWNRFRDRKLDDYIKSWEDNQQGDEALDTTKDPCQKVKCSRHKVCVAQGYQRAMCIS--------------------RKKLEHRIKQPSL------KLHGGKDSICKPCHMAQLASVCGSDGHTYSSVCKLEQQACLSNKHLAVRCEGPCPCPTEQ-----------------------------------------------------------------------------------------------------------------------------------------STASTTDSKSETCTGQDLADLGDRLRDWFQLLRENSKQNGSASSSSSPAG-LDKSLGASCKDSIGWMFSKLDTSGDLFLDQTELAAINLDKYEVCIRPFFNSCDTYKDGRVSTAEWCFCFWREKPPCLAELERTQIQEAAKKKPGIFIPSCDEDGYYRKMQCDQSSGDCWCVDQLGLELTGTRMHGNPDCDDIVGFSGDFGSGVGWEDEEEKETEEAGEEAEEEEGEAGEADDGGYIW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ER58-1", "uniprot_id": "TICN2_MOUSE", "id": "Q9ER58-1", "name": "Testican-2", "aln": "-MRAPGSGRLALPLLLLAVVALAEGDAKGLK------------------EGETPGNFMEDEQWLSSIS-----------------------------------------------QYSGKIKHWNRFRDEVEDDYIKSWEDNQQGDEALDTTKDPCQKVKCSRHKVCVAQGYQRAMCIS--------------------RKKLEHRIKQPSL------KLHGGKDSVCKPCHMAQLASVCGSDGHTYSSVCKLEQQACLSSKQLAVRCEGPCPCPTEQ-----------------------------------------------------------------------------------------------------------------------------------------STASTTDSKSETCTGQDLADLGDRLRDWFQLLRENSKQNGSANSATNPAG-LDKSLGASCKDSIGWMFSKLDTSGDLFLDQTELAAINLDKYEVCIRPFFNSCDTYKDGRVSTAEWCFCFWREKPPCLAELERTQIQEAAKKKPGVFIPSCDEDGYYRKMQCDQSRGDCWCVDQLGLELTGTRMHGTPDCDDIVGFSGDFGSGVGWEDEEEKETEEAGEEAEEEEGEAGEADDGGYIW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92563-1", "uniprot_id": "TICN2_HUMAN", "id": "Q92563-1", "name": "Testican-2", "aln": "-MRAPGCGRLVLPLLLLAAAALAEGDAKGLK------------------EGETPGNFMEDEQWLSSIS-----------------------------------------------QYSGKIKHWNRFRDEVEDDYIKSWEDNQQGDEALDTTKDPCQKVKCSRHKVCIAQGYQRAMCIS--------------------RKKLEHRIKQPTV------KLHGNKDSICKPCHMAQLASVCGSDGHTYSSVCKLEQQACLSSKQLAVRCEGPCPCPTEQ-----------------------------------------------------------------------------------------------------------------------------------------AATSTADGKPETCTGQDLADLGDRLRDWFQLLHENSKQNGSASSVAGPASGLDKSLGASCKDSIGWMFSKLDTSADLFLDQTELAAINLDKYEVCIRPFFNSCDTYKDGRVSTAEWCFCFWREKPPCLAELERIQIQEAAKKKPGIFIPSCDEDGYYRKMQCDQSSGDCWCVDQLGLELTGTRTHGSPDCDDIVGFSGDFGSGVGWEDEEEKETEEAGEEAEEEEGEAGEADDGGYIW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8Q8S3-1", "uniprot_id": "A0A2R8Q8S3_DANRE", "id": "A0A2R8Q8S3-1", "name": "Testican-2", "aln": "MVWMNNPGCVLVPLLMLVRVAMQV-DVKSGK------------------EAEKTGNFMEDEQWLSTIS-----------------------------------------------QYSRKIKHWNRFRD---DDYIRSWDENQGSNENVDTTKDPCQKVKCSRHKVCVAQGYQRAVCVN--------------------RKKLEHRLKQQVI------RQQ--QESNCKPCPVSSSGPVCGSDGHNYASQCKLEQQACLAGKELKVRCPGLCPCTATT-----------------------------------------------------------------------------------------------------------------------------------------APATDVDGKHESCTGQDLADLGDRLRDWFQLLQGNGKQNSTGSPAASSASIVDRTLVATCKDSIGWMFSKLDTNSDLYLDQAELAAINLDKYEVCIRPFFNSCDSYRDGKVSTAEWCLCFWREKPPCLAELERIQLQEGAKKKSDTYIPSCDEDGFYRRLQCDKSRGECWCVDQHGGELMGSRIHGNPDCDEVVTYSGDFGSGLGWEDEEEKEAEENGEEAEEEEGEVGEVDDGGYIW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VCR3-1", "uniprot_id": "COW_DROME", "id": "Q9VCR3-1", "name": "Proteoglycan Cow", "aln": "MKHSPLIASACLALVLMSSSLIGSTEARNKKKYVGETGGDFEFIDEINKNTQSNKNLGEHKRWIHDPSSDLCRPLNCKKREICLLEDEFSAVCVSKKELHKNRDEIITKAKYLEEEAKRRVNQQDNQDSQDAEDINNDDEDNSSDGGSSNSSPTGTNNAQASVQGNEETDDEDKSLSLGDDDESKEDDVFYENSIAAGDKQQQQQQLSQPAAGPSVIQQDDDEELDNCKPCPVAKPTFLCGADNRTYSSLCRLDYHNCIHSTSIRIACKGFCPCKEIVDGKRLQRISGYNNKYNKKISLDQQQQQQQQQQQQQQQQQAYKDSNNNNIMMNSGNIMGGNNNDFNTIMNDKEDNNRHNNHINAQYTFTPEEIKYDNKHYKYLKYTAYKKDSKYQEDKHKMRNYNEVVEKQQQKFNKNSNLNAYPSKSAECKPQQLTAIGNRLLDWFSVIMADSKKRRQHSQKS------KAHFPPACKTEAKWMFGHLDLNNDGQLSLQEMYDLEHDQNERCIKPFIDTCDLDTDSSINTREWCRCFEKTDRPCAAVRRRIAGDFAG-----AYAPDCDIQGFYKPTQCHNSVGVCWCVDKHGVEFANTRTRGKPNCESVVNNAASLTS------------DDEDEGADDEDSAEGSADQMLVF-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :.*::: : :.:. * : :. *: *.::*: * : . :::: :. . :* .. ::*. .. ::: ::.:.* : ::. ::::.:. ::: ::::.* : . : . **** ::. :**:*.:.*:* *:*: : *: .. : : * * *** : . .* *. *:*: :*:** ***.:: :.*:. . : . : .:** . ***.:** . * *. *: :: *: * **:**:::** *. :.* *** ** : . ** * .* : .. : *.** :*:*: **.:* * *****: * *: .:* :*.*:*:.:* :..: * :: .* *::*:. *..*: : ", "identical_positions": 94, "similar_positions": 159, "identity": "14.4%" }, { "cls_id": "homologset.agr.RGD:1308569", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q3MIF2-1", "uniprot_id": "LMBL2_RAT", "id": "Q3MIF2-1", "name": "Lethal(3)malignant brain tumor-like protein 2", "aln": "-----------------------------------------------------------------------------------------------------MEKPRGTEETPSSEPMEEE----------------------------------------EDDDLELFG----------GYDSFRSYN---------------SSAGSE-----------------------------------SSSYLEESSEAENE--------------DREAGELPTSPLHLFSS-ANNRALDGS-------------------------GSEPAVCEMCGIVGTREAFFSKTKRFCSVSCSR------------------SYSSNSKKASILARLQGKPPTKKAKVLHKAAWSAKIGAFLHAQGTGQLADGTP--------------------------------TGQDALVLG------------------------------------------------------------------FDWGKFLKDHSYKAAPVGCFKHVPLYDQWEDVMKGMKVEVLNS--------DAVLPSRVYWIATVIQAAGYRVLLRYEGFENDASHDFWCNLGTVDVHPIGWCAINSKILVPPRTIHAKFTDWKSYLMKRLVGSRTLPADFHIKMVESMKYPFRQGMRLEVVDKTQVSRTRMAVVDTVIGGRLRLLYED------GDSDDDFWCHMWSPLIHPVGWSRRVGHGIKMSERRCD--MSHHPTFRKIYCDAVPYLFKKVRAVYTEGG------WFEEGMKLEAIDPLNLGNICVATICKVLLDGYLMICVDGGP-STDGSDWFCYHASSHAIFPATFCQKNDIELTPPKGYETQPFDWESYLEKTKSKAAPARLFNMDCPNHGFKVGMKLEAVDLMEPRLICVATVKRVVHRLLSIHFDGWDNEYDQWVDCESPDIYPVGWCELTGYQLQPPVSAEPNTPQKGKDATKKKKKQFGKK-------------------------RKRIP--SAKTRPLRQSSKKPLLEDNLEALG----------------------VSEPVPDDIIAVCVKEEHQDLPSPDRSPSPL-LPLPTESIKQERDS------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P59178-1", "uniprot_id": "LMBL2_MOUSE", "id": "P59178-1", "name": "Lethal(3)malignant brain tumor-like protein 2", "aln": "-----------------------------------------------------------------------------------------------------MEKPRGTEEAPSSEPMEEE----------------------------------------EEDDLDLFG----------GYDSFRSYN---------------SSAGSE-----------------------------------SSSYLEESSEAENE--------------DREAGELPTSPLHLFSS-ANNRSLDGS-------------------------GSEPAVCEMCGIVGTREAFFSKTKRFCSVSCSR------------------SYSSNSKKASILARLQGKPPTKKAKVLHKAAWSAKIGAFLHAQGTGQLADGTP--------------------------------TGQDALVLG------------------------------------------------------------------FDWGKFLKDHSYKAAPVSCFKHVPLYDQWEDVMKGMKVEVLNS--------DAVLPSRVYWIATVIQAAGYRVLLRYEGFENDASHDFWCNLGTVDVHPIGWCAINSKILVPPRTIHAKFTDWKSYLMKRLVGSRTLPADFHIKMVESMKYPFRQGMRLEVVDKTQVSRTRMAVVDTVIGGRLRLLYED------GDSDDDFWCHMWSPLIHPVGWSRRVGHGIKMSDRRCD--MSHHPTFRKIYCDAVPYLFKKVRAVYTEGG------WFEEGMKLEAIDPLNLGSICVATICKVLLDGYLMICVDGGP-STDGSDWFCYHASSHAIFPATFCQKNDIELTPPKGYETQPFAWETYLEKTKSKAAPARLFNMDCPNHGFKVGMKLEAVDLMEPRLICVATVKRVVHRLLSIHFDGWDNEYDQWVDCESPDIYPVGWCELTGYQLQPPVSAEPNTPQKGKDTTKKKKKQFGKK-------------------------RKRIP--SAKTRPLRQGSKKPLLEDNLEALG----------------------VSEPVPDDIIAVCVKEEHQDISSLDRSPSPQ-LPLPIESIKQERNN------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q969R5-1", "uniprot_id": "LMBL2_HUMAN", "id": "Q969R5-1", "name": "Lethal(3)malignant brain tumor-like protein 2", "aln": "-----------------------------------------------------------------------------------------------------MEKPRSIEETPSSEPMEEE----------------------------------------EDDDLELFG----------GYDSFRSYN---------------SSVGSE-----------------------------------SSSYLEESSEAENE--------------DREAGELPTSPLHLLSP-GTPRSLDGS-------------------------GSEPAVCEMCGIVGTREAFFSKTKRFCSVSCSR------------------SYSSNSKKASILARLQGKPPTKKAKVLHKAAWSAKIGAFLHSQGTGQLADGTP--------------------------------TGQDALVLG------------------------------------------------------------------FDWGKFLKDHSYKAAPVSCFKHVPLYDQWEDVMKGMKVEVLNS--------DAVLPSRVYWIASVIQTAGYRVLLRYEGFENDASHDFWCNLGTVDVHPIGWCAINSKILVPPRTIHAKFTDWKGYLMKRLVGSRTLPVDFHIKMVESMKYPFRQGMRLEVVDKSQVSRTRMAVVDTVIGGRLRLLYED------GDSDDDFWCHMWSPLIHPVGWSRRVGHGIKMSERRSD--MAHHPTFRKIYCDAVPYLFKKVRAVYTEGG------WFEEGMKLEAIDPLNLGNICVATVCKVLLDGYLMICVDGGP-STDGLDWFCYHASSHAIFPATFCQKNDIELTPPKGYEAQTFNWENYLEKTKSKAAPSRLFNMDCPNHGFKVGMKLEAVDLMEPRLICVATVKRVVHRLLSIHFDGWDSEYDQWVDCESPDIYPVGWCELTGYQLQPPVAAEPATPLKAKEATKKKKKQFGKK-------------------------RKRIP--PTKTRPLRQGSKKPLLEDDPQGARK--------------------ISSEPVPGEIIAVRVKEEHLDVASPDKASSPE-LPVSVENIKQETDD------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B6H7-1", "uniprot_id": "A0ACD6B6H7_DANRE", "id": "A0ACD6B6H7-1", "name": "Lethal(3)malignant brain tumor-like protein 2", "aln": "---------------------------------------------------------------------------------MPYKCVAYGCGKISGQNVSMFRFPKDPEEFSKWQRQVQKTRRYWLA-------------------------NTYSHLCNEHFTKDCFEPKTYVTAKASGFKRLKLKDGAVPTVFIRRRCRKCGGKGVS-----------------------------------CSFCIKKKQEALTQPQQFAPDEQEMTFMDVTENDGENYNQHNFSDDGDNGPVKPSSW----------------------VDDGIVACEMCGTVGSIDTFFSRTKRFCSASCSR------------------SYSSNSKKSSILARLQGRPSKKSS---HKLCPKTQT-EVLRPKVIEQHQESRP--------------------------------FVQDATLAG------------------------------------------------------------------FDWGSYLEKSGLLAAPVSCFRHVPLCAQWEDVYVGLKVEVLNT--------HTALPSKVYWIATVVQLAGYKALLRYEGFEDDDRHDLWCNLGTADVHPIGWCAVNNKPLVPPQEVHQ--QDWKSYLMERLVGAHTIPVDFHVKMADSLRCPFRQGVRVEVVDRSQVSRTRLAVVDTVIGGRLRLLYEDAGLGPSGEVLSDFWCHMQSPLVHHVGWSETVDHSIKETDTNVN--MGSHPAFRRVHQNSVPDQFKKLRTVYMGAT------FFKEGMKIEAIDPLNLGNICVASVRKVLLDGYIMVGIDGVE-IGDGSDWFCYHASSHAILPVGYCENNDIPLTVPPGYDQATFTWPVYLEETGAVAAPQRLFNTDDVGHGFTSGMKLEAVDLMEPRLVCVATVRRCVGRLLLLHFDGWEPEFDQWVDCQSPEIYPVGWCEITGYQLQPPIGPEPPQGQEHSHASKKAKPFKGKR-------------------------KRRFLRKNAKINLKTQTNENTEMIQSQEAANTSDKPS-------------TLQIKTEPEEEVIAVRVKVEELETPILSSAQSKESHQGALTTFKREKDDDEDEEEDEDDDV------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VK33-1", "uniprot_id": "SMBT_DROME", "id": "Q9VK33-1", "name": "Polycomb protein Sfmbt", "aln": "MNPSELRMMWMSSQYNSERITLEDAATLLGHPTVGLSVMEDLSAHQPTLDMNPMMSLMGGDFTGQAAATAAALGVQPGTLIATNSNNLYGFAHMGGLQQQLLQQSAAAAVFQNYAEAMDNDVENGMVGMAMEAVVDDDDQVYGQRDNNFDDNGSELEPKQEIINIDDFVMMNEDNNSYDGTDFMTSSDKDISQSSSSCMAQMPGSLGVPGVEHDLLVPLPDGLLHHKLLGTTLVPAMGTLNGNAFGNIMVSTENTSSKQMQRTYSTAKGANSTATTATCSASTSSALRSQRKTRKIEPVNRPGLVLKTPIAYRGNIDPSVIPIQKDGMAVCKRCGAIGVKHTFYTKSRRFCSMACARGELYSLVLNTKMEGDQATTSSPDPGAGSESADLPGDQQQSQSDIELDLHAAHIKNANYRFRITDQSKITQLNSFGEPMSMGGDAAANNVQMAADETIAALNGGAVGDATAPGSTEEGASTPNSYLSAAPTPKALRLFKDIYPQDDLPQIPKYERLPVPCPQMEKIISIRRRMYDPTHSYDWLPRLSKENFNAAPVTCFPHAPGCEVWDNLGVGMKVEVENTDCDSIEVIQPGQTPTSFWVATILEIKGYKALMSYEGFDTDS-HDFWVNLCNAEVHSVGWCATRGKPLIPPRTIEHKYKDWKDFLVGRLSGARTLPSNFYNKINDSLQSRFRLGLNLECVDKDRISQVRLATVTKIVGKRLFLRYFD--------SDDGFWCHEDSPIIHPVGWATTVGHNLAAPQDYLERMLAGREAMIEVHEDDATIELFKMNFTFDEYYSDGKTNSFVEGMKLEAVDPLNLSSICPATVMAVLKFGYMMIRIDSYQPDASGSDWFCYHEKSPCIFPAGFCSVNNISVTPPNGYDSRTFTWEGYLRDTGAVAAGQHLFHRIIPDHGFEVGMSLECADLMDPRLVCVATVARVVGRLLKVHFDGWTDEYDQWLDCESADIYPVGWCVLVNHKLEGPPRVAHQQAPKPAPKPKIQRKRKPKKGAAGGKTPTDNNTQSVKSRTIALKTTPHLPKLSIKLELKPEHHNAAFYENNQPEEEGDEEDPDADGDGDGSTSHISEQSTTQSSSDLIAGSGSGSGSASLVTLATGSNKTNSSATNNKYIPRLADIDSSEPHLELVPDTWNVYDVSQFLRVNDCTAHCDTFSRNKIDGKRLLQLTKDDIMPLLGMKVGPALKISDLIAQLKCKVNPGRARSHKTNKSPFL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . . :: * : * * . : : .. * . : ...:: .: : :. . ..*: ** :* .:*:::::**** :*:* : *.:. .* * * * ..: . : : * ** * :** *.. . **** ** *.* *::: *:**** *: .. .. :*:*:::: **:.*: ****: * **:* ** ..:**.:**** ..* *:**: :. ***.:*: ** *::*:* :*: *: :*:: ** *:.:* **: ::*:.*:*.* .::* ** * * * ..**** **::* ***: *.*.: .: : :. : :: .:: : .. : *:. .: * ****:**:*****..** *:: ** **:*: :*. .* ****** .* .*:*. :*. *:* :* * **: .* * **..* : ** :**: .*** **.**..***:***:***** * * *** :***** *:***:**:*.:******* :..::*: * : .* : *: :: * . : : . :. . ::** . . : * . . ", "identical_positions": 205, "similar_positions": 201, "identity": "16.68%" }, { "cls_id": "homologset.agr.RGD:1308570", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8NBU5-1", "uniprot_id": "ATAD1_HUMAN", "id": "Q8NBU5-1", "name": "Outer mitochondrial transmembrane helix translocase", "aln": "----MVHAEAFSRPLSRNEVVGLIFRLTIFGAVTYFTIKWMVDAIDP------TRKQKVEAQKQAEKLMKQIGV---------KNVKLSEYEMSIAAHLVDPLNMHVTWSDIAGLDDVITDLKDTVILPIKKKHLFENSRLLQPPKGVLLYGPPGCGKTLIAKATAKEAGCRFINLQPSTLTDKWYGESQKLAAAVFSLAIKLQPSIIFIDEIDSFLRNRSSSDHEATAMMKAQFMSLWDGLDTDHSCQVIVMGATNRPQDLDSAIMRRMPTRFHINQPALKQREAILKLILKNENVDR-HVDLLEVAQETDGFSGSDLKEMCRDAALLCVREYVNSTSEESHDEDEIR------------------PVQQQDLHRAIEKMKKSKDAAFQNVLT-HVCLD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9D5T0-1", "uniprot_id": "ATAD1_MOUSE", "id": "Q9D5T0-1", "name": "Outer mitochondrial transmembrane helix translocase", "aln": "----MVHAEAFSRPLSRNEVVGLIFRLTIFGAVTYFTIKWMVDAIDP------TRKQKVEAQKQAEKLMKQIGV---------KNVKLSEYEMSIAAHLVDPLNMHVTWSDIAGLDDVITDLKDTVILPIKKKHLFENSRLLQPPKGVLLYGPPGCGKTLIAKATAKEAGCRFINLQPSTLTDKWYGESQKLAAAVFSLAIKLQPSIIFIDEIDSFLRNRSSSDHEATAMMKAQFMSLWDGLDTDHSCQVIVMGATNRPQDLDSAIMRRMPTRFHINQPALKQREAILKLILKNENVDR-HVDLLEVAQETDGFSGSDLKEMCRDAALLCVREYVNSTSEESHDEDEIR------------------PVQQQDLHRAIEKMKKSKDAAFQNVLT-HVCLD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q505J9-1", "uniprot_id": "ATAD1_RAT", "id": "Q505J9-1", "name": "Outer mitochondrial transmembrane helix translocase", "aln": "----MVHAEAFSRPLSRNEVVGLIFRLTIFGAVTYFTIKWMVDAIDP------TRKQKVEAQKQAEKLMKQIGV---------KNVKLSEYEMSIAAHLVDPLNMHVTWSDIAGLDDVITDLKDTVILPIKKKHLFENSRLLQPPKGVLLYGPPGCGKTLIAKATAKEAGCRFINLQPSTLTDKWYGESQKLAAAVFSLAIKLQPSIIFIDEIDSFLRNRSSSDHEATAMMKAQFMSLWDGLDTDHSCQVIVMGATNRPQDLDSAIMRRMPTRFHINQPALKQREAILKLILKNENVDR-HVDLLEVAQETDGFSGSDLKEMCRDAALLCVREYVNSTSEESHDEDEIR------------------PVQQQDLHRAIEKMKKSKDAAFQSVLT-HVCLD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q503W7-1", "uniprot_id": "ATD1B_DANRE", "id": "Q503W7-1", "name": "Outer mitochondrial transmembrane helix translocase", "aln": "MVLKEIPTENITRPLGRNEVIGLLFRLTIFGAVTYFTIKWMVDAIDP------TRKQKVEAQKQAEKLMRQIGV---------QNVKLSEYEMSIAAHLVDPLTMQITWHDIAGLDEVITELKDTVILPIQKRHLFEGSRLLQPPKGVLLYGPPGCGKTLIAKATAKEAGFRFINLQPSTLTDKWYGESQKLAAAVFSLAIKLQPSIIFIDEIDSFLRNRSSSDHEATAMMKAQFMSLWDGLDTDYNCQVIIMGATNRPQDLDSAILRRMPTRFHINQPNVRQRKDILKLILENENVES-AVELSEIAKQTDGFSGSDLREMCRDAALLCVRDFVH---QESPEEDFIR------------------PIRQEDLQRAIEKMKKSKSAGVHEAFM-QVPLD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VL02-1", "uniprot_id": "Q9VL02_DROME", "id": "Q9VL02-1", "name": "", "aln": "----MDNFGLGGSDLSKGQIFQVLVRLSVASLITYYSVKWMMNQMDP------TSKNKKKAKVLAEEQLKRLAE---QEGFKLRGQEFSDYELMIASHLVVPADITVSWADIAGLDSVIQELRESVVLPIQHKDLFKHSKLWQAPKGVLLHGPPGCGKTLIAKATAKEAGMRFINLDVAILTDKWYGESQKLTSAVFSLASRIEPCIIFIDEIDSFLRSRNMNDHEATAMMKTQFMMLWDGLSTNANSTVIVMGATNRPQDLDKAIVRRMPAQFHIGLPSETQRKDILKLILQSEEVSQ-DVDLNRLSKLTNGFSGSDLREMCRNASVYRMRQLITSRDPSATALDRN-----------------NVRITMDDLLGSHLKIKESKMHTSSLFLENRIELD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V3Q1-1", "uniprot_id": "Q9V3Q1_DROME", "id": "Q9V3Q1-1", "name": "AAA+ ATPase domain-containing protein", "aln": "----MD-----SQEGTQCQILAIVIRVCVFSALTYYTAKWMINALDP------NNKIRGKAKYVAEEQLRKLNSSAIGAAKKFRARDFNEHEMMIASHLVTPEDIDISWSDIAGLDGTIQELRETVVLPVRHRKLFSRSKLWRAPKGVLLHGPPGCGKTLIAKAIAKDAGMRFINLDVGVLTDKWYGESQKLATAVFTLAKKLQPCIIFIDEIESFLRMRGSNDHEATAMIKTQFMLQWDGLMSNTNICVLVLGATNRPQDLDKAILRRMPAQFHIGVPRDCQRREILQLILQTEQLSP-SVNLKELARLTIGFSGSDLRELCRHASMYRMRQFMREKLNTGEEIGKDKIEWDFEVKDQALQEWEHLEIQMEDLLKSLSVMKASKHQAQGTFLEKDLELD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P28737-1", "uniprot_id": "MSP1_YEAST", "id": "P28737-1", "name": "Outer mitochondrial transmembrane helix translocase", "aln": "----------MSRKFDLKTITDLSVLVGTG-ISLYYLVSRLLNDVESGPLSGKSRESKAKQSLQWEKLVKRSPA--------LAEVTLDAYERTILSSIVTPDEINITFQDIGGLDPLISDLHESVIYPLMMPEVYSNSPLLQAPSGVLLYGPPGCGKTMLAKALAKESGANFISIRMSSIMDKWYGESNKIVDAMFSLANKLQPCIIFIDEIDSFLRERSSTDHEVTATLKAEFMTLWDGLLNNG--RVMIIGATNRINDIDDAFLRRLPKRFLVSLPGSDQRYKILSVLLKDTKLDEDEFDLQLIADNTKGFSGSDLKELCREAALDAAKEYIKQKRQLIDSGTIDVN---------------DTSSLKIRPLKTKDFTKKLRMDATSTLSS--QPLD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . : *: . ::: ::. . : : : . *: ::: :. :* * : :* * : ::: **.*** * :*:::*: *: .::. * * :.*.****:********::*** **::* .**.: . : *******:*:. *:*:** :::*.*******:**** *. .***.** :*::** **** .: *:::***** :*:*.*::**:* :* :. * ** **.::*: ::. .:* :: * *******:*:**.*:: :: : : * : **", "identical_positions": 110, "similar_positions": 105, "identity": "27.5%" }, { "cls_id": "homologset.agr.RGD:1308574", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZTV3-1", "uniprot_id": "FLRT2_RAT", "id": "D3ZTV3-1", "name": "Leucine-rich repeat transmembrane protein FLRT2", "aln": "MGLQTAKWPSHGTFVLKFWLIMSLGLYSHVSKLLACPSVCRCDRNFVYCNERSLTSVPLGIPEGVTVLYLHNNQINNAGFPAELHNVQSVHTVYLYGNQLDEFPMNLPKNVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREAISLKLLFLSKNHLSSVPVGLPVDLQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIADGTFSHLTKLKEFSIVRNSLSHPPPDLPGTHLIRLYLQDNQINHIPLTAFANLRKLERLDISNNQLRMLTQGVFDHLSNLKQLTARNNPWFCDCSIKWVTEWLKYIPSSLNVRGFMCQGPEQVRGMAVRELNMNLLSCPTTTPGLPVFTPAPSTVSPTTQSPTVSVPSPSRGSVPPAPAPSKLPTIPDWDGRERATPPISER---IQLSIHFVNDTSIQVSWLSLFTVMAYKLTWVKMGHSLVGGIVQERIVSGEKQHLSLVNLEPRSTYRICLVPLDAFN-YRTVEDTICSEATTHASYLNNGSNTASSHEQTTSHTMGSPFLLAGLIGGAVIFVLVVLLSVFCWHMHKKGRYTSQKWKYNRGRRKDDYCEAGTKKDNSILEMTETSFQIVSLNNDQLLKGDFRLQPIYTPNGGINYTDCHIPNN-MRYCNSSVPDLEHCHT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BLU0-1", "uniprot_id": "FLRT2_MOUSE", "id": "Q8BLU0-1", "name": "Leucine-rich repeat transmembrane protein FLRT2", "aln": "MGLQTTKWPGRGAFILKFWLIISLGLYLQVSKLLACPSVCRCDRNFVYCNERSLTSVPLGIPEGVTVLYLHNNQINNAGFPAELHNVQSVHTVYLYGNQLDEFPMNLPKNVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREAISLKLLFLSKNHLSSVPVGLPVDLQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKEFSIVRNSLSHPPPDLPGTHLIRLYLQDNQINHIPLTAFANLRKLERLDISNNQLRMLTQGVFDHLSNLKQLTARNNPWFCDCSIKWVTEWLKYIPSSLNVRGFMCQGPEQVRGMAVRELNMNLLSCPTTTPGLPVFTPAPSTVSPTTQSPTLSVPSPSRGSVPPAPTPSKLPTIPDWDGRERVTPPISER---IQLSIHFVNDTSIQVSWLSLFTVMAYKLTWVKMGHSLVGGIVQERIVSGEKQHLSLVNLEPRSTYRICLVPLDAFN-YRTVEDTICSEATTHASYLNNGSNTASSHEQTTSHSMGSPFLLAGLIGGAVIFVLVVLLSVFCWHMHKKGRYTSQKWKYNRGRRKDDYCEAGTKKDNSILEMTETSFQIVSLNNDQLLKGDFRLQPIYTPNGGINYTDCHIPNN-MRYCNSSVPDLEHCHT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43155-1", "uniprot_id": "FLRT2_HUMAN", "id": "O43155-1", "name": "Leucine-rich repeat transmembrane protein FLRT2", "aln": "MGLQTTKWPSHGAFFLKSWLIISLGLYSQVSKLLACPSVCRCDRNFVYCNERSLTSVPLGIPEGVTVLYLHNNQINNAGFPAELHNVQSVHTVYLYGNQLDEFPMNLPKNVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREAISLKLLFLSKNHLSSVPVGLPVDLQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKEFSIVRNSLSHPPPDLPGTHLIRLYLQDNQINHIPLTAFSNLRKLERLDISNNQLRMLTQGVFDNLSNLKQLTARNNPWFCDCSIKWVTEWLKYIPSSLNVRGFMCQGPEQVRGMAVRELNMNLLSCPTTTPGLPLFTPAPSTASPTTQPPTLSIPNPSRSYTPPTPTTSKLPTIPDWDGRERVTPPISER---IQLSIHFVNDTSIQVSWLSLFTVMAYKLTWVKMGHSLVGGIVQERIVSGEKQHLSLVNLEPRSTYRICLVPLDAFN-YRAVEDTICSEATTHASYLNNGSNTASSHEQTTSHSMGSPFLLAGLIGGAVIFVLVVLLSVFCWHMHKKGRYTSQKWKYNRGRRKDDYCEAGTKKDNSILEMTETSFQIVSLNNDQLLKGDFRLQPIYTPNGGINYTDCHIPNN-MRYCNSSVPDLEHCHT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "X1WEV4-1", "uniprot_id": "X1WEV4_DANRE", "id": "X1WEV4-1", "name": "", "aln": "MEVQIRMWNKDLPALISPWIPILLGLHMHFSWATTCPEECRCDRTFVYCNERSLTSVPLGLGEGYKTLYLHNNQINNAGFPLEMHNVASVETVYLYGNQLDEFPVNLPKNVRVLHLQENNIQTVSRAALAQLLRLEELYLDDNSISTVGVEEGAFREAISLKTIFLTKNHLSSIPIGLPEELRELRLDENRIALITEDAFENVTGLELLLLDGNLLTDEGITPGSLQTLANLKTLSMARNSLTVPPPNLPTEFLIKLNLQDNQMNEIPLTAFRGLHRLERLDISNNQLQSLTQGVFDGLHSLRQLTVRNNLWLCDCDIKWVILWLKSLPATLNVRGFMCQKPERVRGMVIRELTLELIQCPNSTGTVPQPT-LLSSSTAESATQTAFTPARTQPTPSPPPLTLLLPTT-GEDIEQRTNDPIGPRQESMRISFVVLNSSCIQVSWVSTFAVTAYKVTWVKLSPNLITGPMQESLVEGKLDGITLRNLEPKSTYRICVDPLDAFNNYHPGDDTICSEVTTKSASFHSGDN-ATGPEQATQQDPSSPFLLAGLIGGAVLVVLVVLLSIFCWHMHKKGRSDSSKWKYSRGRRKDDYCEAGTKKDNSILEMTETSFQIVSLNNEQLLKGDFHIQPIYTPNGGVGFRDSQRRNNSTAYCKNSVPESDTCHK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :* * . .:. *: : ***: :.* :**. *****.***************: ** ..************** *:*** **.*************:******************:*********:****:************:********** :**:******:*:*** :*:***:******:*:: **:*:*.** *::******::**: *::. *::** :*:.****: ***:** .**:* *****:*.****** .*::***********: ******* * .*:***.*** *:***.**** *** :*::********* **:****.:***.::*:.**.:* :* * *: :. : . * * :: .*.* . *** . * .:*.. **. * :::*: .:*.:.*****:* *:* ***:****:. .*: * :** :*.*: : ::* ****:******: ****** *:. :******.**::: ::.*.* *:. **:*.: .*************:.*******:********** *.****.**********************************:*******::*********:.: *.: ** **:.***: : **.", "identical_positions": 411, "similar_positions": 154, "identity": "61.8%" }, { "cls_id": "homologset.agr.RGD:1308576", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZSB2-1", "uniprot_id": "A0A8I5ZSB2_RAT", "id": "A0A8I5ZSB2-1", "name": "", "aln": "MNYPGRGAPRSPERNGRGGG--AWELGSDAAGVFGGGGCCFEHQPGDG-----VPLSLLRAEP-LHLAPGADDL-SHLALDPCLSDENYDFSSAESGSSLRYYSEGESAGGGSSSSPPPP----LVAPNSGGGGAAGGGPGDRKRSRPGGCAARHRYEVVTELGPEEVRWFYKEDKKTWKPFIG-YDSLRIELAFRSLLQTTGSRARSADRDGDRVCGPT----SSFREDDEDRACGFCPRAVGPEPEMEELVTIEPVCVRGGLYEVDVTQGECYPVYWNQADKIPVMRGQWFIDGTWQPLEEEESNLIEQEHLSCFRGQQMQENFDIEMSKSIDGKDVVYHIPPFSLPSLFKWRGYKESTDATGLKRKRSQAVHSFKLSRNHVDWHSMDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEATLEDKPSQTSHIVFVVHGIGQKMDQGRIIKNTAMMREAARKIEEKHFANHATHVEFLPVEWRSKLTLDGDTVDSITPDKVRGLRDMLNSSAMDIMYYTSPLYRDELVKGLQQELNRLYSLFCSRNPDFEEKGGKVSIVSHSLGCVITYDIMMGWNPVRLYEQLLQKEEELPDERWMSYEERHLLDELYITKRRLREIEDRLHGLKAPSGSQTPALKFKVENFFCMGSPLAVFLALRGIRPGNTGSQDHILPREICNRLLNIFHPTDPVAYRLEPLILKHYSNISPVQIHWYNTSNPLPYEHMKPNFLNPAKEPTSASESENIAAIPSPVTSPVLSRRHYGESITN--IGKASILGAASIG------KGLGGMLFSRFGRSSTPQPSEPSKDSAEEEKKPVSSPSTTTVATQTLPHSSSGF-LDSAYFRLQESFFYLPQLLFPENVMQSKDD----------------SLVELEHRIDFELREGLVESRYWSAVTSHTAYWSSLDVALFLLTFMY-KHEHDSEAKTSLDSI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80YA3-1", "uniprot_id": "DDHD1_MOUSE", "id": "Q80YA3-1", "name": "Phospholipase DDHD1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEATLEDKPSQTSHIVFVVHGIGQKMDQGRIIKNTAMMREAARKMEEKHFSNHATHVEFLPVEWRSKLTLDGDTVDSITPDKVRGLRDMLNSSAMDIMYYTSPLYRDELVKGLQQELNRLYSLFCSRNPDFEEKGGKVSIVSHSLGCVITYDIMMGWNPGGLYEQLLQKEEELPDERWMSYEERHLLDELYITKRRLREIEDRLHGLKAPSISQTPALKFKVENFFCMGSPLAVFLALRGIRPGNSGSQDHILPREICNRLLNIFHPTDPVAYRLEPLILKHYSNISPVQIHWYNTSNPLPYEHMKPNFLNPAKEPTSVSDSENIAAIPSPVTSPVLSRRHYGESITN--IGKASILGAASIG------KGLGGMLFSRFGRSSASQPSEPSKDSLEDDKKPSASPSTTTVATQTLPHSGSGF-LDSAYFRLQESFFYLPQLLFPENVMQSKDD----------------SLVELEHRIDFELREGLVESRYWSAVTSHTAYWSSLDVALFLLTFMY-KHEHDTEAKPSLGSL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NEL9-1", "uniprot_id": "DDHD1_HUMAN", "id": "Q8NEL9-1", "name": "Phospholipase DDHD1", "aln": "MNYPGRGSPRSPEHNGRGGGGGAWELGSDARPAFGGGVCCFEHLPGGDPDDGDVPLALLRGEPGLHLAPGTDDHNHHLALDPCLSDENYDFSSAESGSSLRYYSEGESGGGGSSLSLHPPQQPPLVPTNSGGGGATGGSPGERKRTRLGGPAARHRYEVVTELGPEEVRWFYKEDKKTWKPFIG-YDSLRIELAFRTLLQTTGARPQGGDRDGDHVCSPTGPASSSGEDDDEDRACGFCQSTTGHEPEMVELVNIEPVCVRGGLYEVDVTQGECYPVYWNQADKIPVMRGQWFIDGTWQPLEEEESNLIEQEHLNCFRGQQMQENFDIEVSKSIDGKD----------------------------------AVHSFKLSRNHVDWHSVDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEATLEDKPSQTTHIVFVVHGIGQKMDQGRIIKNTAMMREAARKIEERHFSNHATHVEFLPVEWRSKLTLDGDTVDSITPDKVRGLRDMLNSSAMDIMYYTSPLYRDELVKGLQQELNRLYSLFCSRNPDFEEKGGKVSIVSHSLGCVITYDIMTGWNPVRLYEQLLQKEEELPDERWMSYEERHLLDELYITKRRLKEIEERLHGLKASSMTQTPALKFKVENFFCMGSPLAVFLALRGIRPGNTGSQDHILPREICNRLLNIFHPTDPVAYRLEPLILKHYSNISPVQIHWYNTSNPLPYEHMKPSFLNPAKEPTSVSENEGISTIPSPVTSPVLSRRHYGESITN--IGKASILGAASIG------KGLGGMLFSRFGRSSTTQSSETSKDSMEDEKKPVASPSATTVGTQTLPHSSSGF-LDSAYFRLQESFFNLPQLLFPENVMQNKDN----------------ALVELDHRIDFELREGLVESRYWSAVTSHTAYWSSLDVALFLLTFMY-KHEHDDDAKPNLDPI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q12204-1", "uniprot_id": "YOR22_YEAST", "id": "Q12204-1", "name": "Probable phospholipase YOR022C, mitochondrial", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------MLRFTHRGLPSSTRFRNIFVRLNHIYVPWFYAIDVPNSKPYLPTYQTLHSPKKFKPFSVDDSNRLEKASKRQERR---------------------------------------PVLVNEDYLFKVDLSHMELSPTYWEGP-TYQVRRGVWFDS-SNQPLSSDLTSEIEGLYKQLKFDDSNDD--------------------------------------------------PTTTPPAESQDIFRLKGKYPVDKENEGEQKNGSSNKD--ENESTFKFILFANKQTAFLLSDLDGGKLQLAFLRSNLAQSLPINATMITRSYKYSSSATTKQTSTSFKAAKTPQTEVADGSNSSKS----RSIETKLEKKVSNLFNLSDFLQLFNGNASKDQDDAQSLEKQMETDYN-----NADNSQGANASSKIEDGKNSGASDRQIR--SNRRDVDNLILCVHGIGQTLGKKYEYVNFAHTVNLLRSNMKKIYNNSEKLQSLNTAPDYKSNCNVQ-VLPITWRHSISFQTDAKEENIENPDLPTLSQVTVNGVLPLRKLLADGLLDILLYVEPYYQDMILQQVTSQLNKTYRIFKEFNPEFDGKVHLVGHSLGSMILFDILSKQKKYELEFQVDNLFFIGSPIGLLKLIQRTKIGDRPEFPNDLERKLTVQRPQCKDIYNVYHVCDPISYRMEPLVSKEMAHYEQTYLPHCSEAYGLTSKVLEFGENIWKDLPGTDENNLQSKKTSPEKKEVKLSENLTRMLTGLNYTGRLDYAMSPSLLEVDFISAIKSHVSYFEEPDIAAFILKEILSKHENASEIYVKRKTG", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. * .. . .: . ::* .: *: *. . *.* . . ::.*: .:.*.: . : . : .:: . :: : :*::. * *: : . ** .. : : :::* * : :: .. :: .:.*::::: *. *.* .: .. * :... .. : : . ::*: . : : .** :: . : : : .:::* :. . *:: . : : :*: .: : :: : . . . ..: *.: * :* : : : : :*.:: *: ... ::.::*.* . .: . : * * .. *. : . : . ** .:: :.** :.* * : :.. *. . :* * . : ***....: * * :.: *.:: :*: ..* . : :: *:*: : .*:* : **:.**.:*:.. *:* *:*. : ***: : . . ", "identical_positions": 69, "similar_positions": 210, "identity": "7.18%" }, { "cls_id": "homologset.agr.RGD:1308577", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q80UP5-1", "uniprot_id": "AN13A_MOUSE", "id": "Q80UP5-1", "name": "Ankyrin repeat domain-containing protein 13A", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSARDTSSRFPLHLLVWNNDYEQLEKELRDQNAEALDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENGQGWTVLHEAVSTGDPEMVYTVLQHRDYHNTSMALEGVPELLHKILEAPDFYVQMKWEFTSWVPLVSRICPNDVCRIWKSGAKLRVDITLLGFENMSWIRGRRSFIFKGGDNWAELMEVNHDDRVVTTEHFDLSQEMERLTLDLMKPKSREVERRLTSPVINTSLDTKNVAFERTKSGFWGWRTDKAEVVNGYEAKVYSVNNVSVITRIRTEHLTEEEKKRYKEDRNPLESLLGTVEHQFGAQG-DLATECATVNNPTAITPDEYFDEDFDLKDRDIGRPKELTIRTQKFKATLWMCEEFPLSLVEQVIPIIDLMARTSAHFARLRDFIKLDFPPGFPVKIEIPLFHVLNARITFGNVNGCSTADE--SQGVEGTPAEAVS-EATNFEVDQSVFEIPESYHIQDNGRNVHLQDEDYEIMQFAIQQSLLESSRSQDLSGPASNGGVSHTHSYEAQYERAIQESLLTNMEGRCPGGLSESSRFDSDLQLAMELSAKELAERELRLQEEEAELQQVLQLSLTEK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZL63-1", "uniprot_id": "A0A8I5ZL63_RAT", "id": "A0A8I5ZL63-1", "name": "", "aln": "MVSDQSRKAAAEGGSSPMVWSRPARAPPGGRADGRGPIVERTTGEGRAGDESRRARTVGFVRGDLGLPKGPAVPQNGGGRVSRRGGLVGRHGAGLGPFRKSGPPPRSVMERLAYFPVRGGSAGSSRFASCQRGRERAGRGVGAAERVPEPVPSPARDPGPPAPPAPDSEALVVRCARHLAARRSPPLALRPVGRAPETPSGGSRLVAGGRSGLGGDLLAMSSARDTSSRFPLHLLVWNNDYRQLEKELRDQNAEALDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENGQGWTVLHEAVSTGDPEMVYTVLQHRDYHNTSMALEGVPELLHKILEAPDFYVQMKWEFTSWVPLVSRICPNDVCRIWKSGAKLRVDITLLGFENMSWIRGRRSLIFKGGDNWAELMEVNHDDRVVTTEHFDLSQEMERLTLDLMKPKSREVERRLTSPVINTSLDTKNVAFERTKSGFWGWRTDKAEVVNGYEAKVYSVNNVSVITKIRTEHLTEEEKKRYKEDRNPLESLLGTVEHQFGAQGQDLTTECATVNNPTAITPDEYFDEDFDLKDRDIGRPKELTIRTQKFKATLWMCEEFPLSLVEQVIPIIDLMARTSAHFARLRDFIKLDFPPGFPVKIEIPLFHVLNARITFGNVNGCSTAEE--RQSVEGTQAECAASDATNFEVDQSVFEIPESYHVQDNGRNVHLQDEDYEIMQFAIQQSLLESSRSQDLSGPASNGGVSHAHSYEAQYERAIQESLLTNMEGRCPGGLSDSSRFDSDLRLAMELSAKELAEQELRLQEEEAELQQVLQLSLTEK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8IZ07-1", "uniprot_id": "AN13A_HUMAN", "id": "Q8IZ07-1", "name": "Ankyrin repeat domain-containing protein 13A", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSACDAGDHYPLHLLVWKNDYRQLEKELQGQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPEMVYTVLQHRDYHNTSMALEGVPELLQKILEAPDFYVQMKWEFTSWVPLVSRICPNDVCRIWKSGAKLRVDITLLGFENMSWIRGRRSFIFKGEDNWAELMEVNHDDKVVTTERFDLSQEMERLTLDLMKPKSREVERRLTSPVINTSLDTKNIAFERTKSGFWGWRTDKAEVVNGYEAKVYTVNNVNVITKIRTEHLTEEEKKRYKADRNPLESLLGTVEHQFGAQG-DLTTECATANNPTAITPDEYFNEEFDLKDRDIGRPKELTIRTQKFKAMLWMCEEFPLSLVEQVIPIIDLMARTSAHFARLRDFIKLEFPPGFPVKIEIPLFHVLNARITFGNVNGCSTAEESVSQNVEGTQADSAS-HITNFEVDQSVFEIPESYYVQDNGRNVHLQDEDYEIMQFAIQQSLLESSRSQELSGPASNGGISQTNTYDAQYERAIQESLLTSTEGLCPSALSETSRFDNDLQLAMELSAKELEEWELRLQEEEAELQQVLQLSLTDK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **** *:..::*******:***.******:.**.**:********************************** *****************************************:*************************************************************:**** *************:*****:***************************************:****************************:****.***:*************** ******************** **:*****.************:*:*********************** **************************************:********************************:* *.**** *:..: . ****************::********************************:*********:*::::*:*************. ** **..**::****.**:********** * ********************:*", "identical_positions": 528, "similar_positions": 48, "identity": "65.1%" }, { "cls_id": "homologset.agr.RGD:1308578", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WVS2-1", "uniprot_id": "OSGEP_RAT", "id": "Q9WVS2-1", "name": "tRNA N6-adenosine threonylcarbamoyltransferase", "aln": "MP--------------AVLGFEGSANKIGVGVVR----------------DGTVLANPRRTYVTAPGTGFLPGDTARHHRAVILDLLQEALTEAGLTPK--DIDCIAYTKGPGMGAPLASVAVVARTVAQLWNKPLLGVNHCIGHIEMGRLITGAVNPTVLYVSGGNTQVISYSEHRYRIFGETIDIAVGNCLDRFARVLKISNDPSPGYNIEQMAKRG---KKLVELPYTVKGMDVSFSGILSFIEDAAQ--------------RMLATGECTPEDLCFSLQETVFAMLVEITERAMAHCGSKEALIVGGVGCNVRLQEMMATMCQERG-AQLFATDERFCIDNGAMIAQAGWEMFQAG-HRTPLQDSGITQRYRTDEVEVTWRD-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BWU5-1", "uniprot_id": "OSGEP_MOUSE", "id": "Q8BWU5-1", "name": "tRNA N6-adenosine threonylcarbamoyltransferase", "aln": "MP--------------AVLGFEGSANKIGVGVVR----------------DGTVLANPRRTYVTAPGTGFLPGDTARHHRAVILDLLQEALAEAGLTSK--DIDCIAFTKGPGMGAPLASVAVVARTVAQLWNKPLLGVNHCIGHIEMGRLITGAVNPTVLYVSGGNTQVISYSEHRYRIFGETIDIAVGNCLDRFARVLKISNDPSPGYNIEQMAKRG---KKLVELPYTVKGMDVSFSGILSFIEDAAQ--------------RMLATGECTPEDLCFSLQETVFAMLVEITERAMAHCGSKEALIVGGVGCNLRLQEMMGTMCQERG-AQLFATDERFCVDNGAMIAQAGWEMFQAG-HRTPLKDSAITQRYRTDEVEVTWRD-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NPF4-1", "uniprot_id": "OSGEP_HUMAN", "id": "Q9NPF4-1", "name": "tRNA N6-adenosine threonylcarbamoyltransferase", "aln": "MP--------------AVLGFEGSANKIGVGVVR----------------DGKVLANPRRTYVTPPGTGFLPGDTARHHRAVILDLLQEALTESGLTSQ--DIDCIAYTKGPGMGAPLVSVAVVARTVAQLWNKPLVGVNHCIGHIEMGRLITGATSPTVLYVSGGNTQVIAYSEHRYRIFGETIDIAVGNCLDRFARVLKISNDPSPGYNIEQMAKRG---KKLVELPYTVKGMDVSFSGILSFIEDVAH--------------RMLATGECTPEDLCFSLQETVFAMLVEITERAMAHCGSQEALIVGGVGCNVRLQEMMATMCQERG-ARLFATDERFCIDNGAMIAQAGWEMFRAG-HRTPLSDSGVTQRYRTDEVEVTWRD-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5RHZ6-1", "uniprot_id": "OSGEP_DANRE", "id": "Q5RHZ6-1", "name": "tRNA N6-adenosine threonylcarbamoyltransferase", "aln": "MT--------------IVIGFEGSANKIGIGIIK----------------DGEVLSNPRRTYITPPGQGFLPGETAKHHRSVILTVLQEALDEAGLKAA--DIDCVAYTKGPGMGAPLVTVAIVARTVAQLWGKPLLGVNHCIGHIEMGRLITNAQNPTVLYVSGGNTQVIAYSERRYRIFGETIDIAVGNCLDRFARVIKISNDPSPGYNIEQMAKKG---NKYIELPYTVKGMDVSFSGILSYIEDAAH--------------KMLSTDQCTPEDLCFSLQETVFAMLVEITERAMAHCGSQEVLIVGGVGCNLRLQEMMGVMCKERG-ARIFATDESFCIDNGAMIAQAGWEMFRSG-HVTELPDSWITQRYRTDEVEVTWRD-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VV41-1", "uniprot_id": "OSGEP_DROME", "id": "Q9VV41-1", "name": "Probable tRNA N6-adenosine threonylcarbamoyltransferase", "aln": "MV--------------CALGIEGSANKIGIGIIR----------------DGKVLANVRRTYITPPGEGFLPKETAKHHREAILGLVESSLKEAQLKSS--DLDVICYTKGPGMAPPLLVGAIVARTLSLLWNIPLLGVNHCIGHIEMGRLITGAQNPTVLYVSGGNTQVIAYSNKRYRIFGETIDIAVGNCLDRFARIIKLSNDPSPGYNIEQLAKSS---NRYIKLPYVVKGMDVSFSGILSYIEDLAEPGKRQNKRK---KPQEEEVNNYSQADLCYSLQETIFAMLVEITERAMAHCGSNEVLIVGGVGCNERLQEMMRIMCEERG-GKLFATDERYCIDNGLMIAHAGAEMFRSG-TRMPFEESYVTQRFRTDEVLVSWRDD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36132-1", "uniprot_id": "KAE1_YEAST", "id": "P36132-1", "name": "tRNA N6-adenosine threonylcarbamoyltransferase", "aln": "MVNLNTIPPKNGRDYYIALGLEGSANKLGVGIVKHPLLPKHANSDLSYDCEAEMLSNIRDTYVTPPGEGFLPRDTARHHRNWCIRLIKQALAEADIKSPTLDIDVICFTKGPGMGAPLHSVVIAARTCSLLWDVPLVGVNHCIGHIEMGREITKAQNPVVLYVSGGNTQVIAYSEKRYRIFGETLDIAIGNCLDRFARTLKIPNEPSPGYNIEQLAKKAPHKENLVELPYTVKGMDLSMSGILASIDLLAKDLFKGNKKNKILFDKTTGEQKVTVEDLCYSLQENLFAMLVEITERAMAHVNSNQVLIVGGVGCNVRLQEMMAQMCKDRANGQVHATDNRFCIDNGVMIAQAGLLEYRMGGIVKDFSETVVTQKFRTDEVYAAWRD-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* .:*:******:*:*::: :. :*:* * **:*.** **** :**:*** : :::.:* *: :.. *:* :.:******..** .:.*** : **. **:************* ** * .*.************:**::********:***:********* :*:.*:*********:** . :. ::***.*****:*:****: *: *. : : : ***:****.:************** .*::.********* ****** **::*. .::.***: :*:*** ***:** :: * : :: :**::***** .:*** ", "identical_positions": 188, "similar_positions": 92, "identity": "48.58%" }, { "cls_id": "homologset.agr.RGD:1308579", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AYR6-1", "uniprot_id": "HDHD2_RAT", "id": "Q6AYR6-1", "name": "Haloacid dehalogenase-like hydrolase domain-containing protein 2", "aln": "MAARRVLKAVLVDLSGTLHIEDAAVPGAQEALKRLRAASVMVRFVTNTTKESKRDLLERLRKLEFDISEEEIFTSLTAARNLIEQRQVRPMLLVDDRALPDFTGVQTH-DPNAVVIGLAPEHFHYQLLNEAFRLLLDG--APLIAIHKARYYKRKDGLALGPGPFVTALEYATDTKAVVVGKPEKTFFLEALRDTDCAPEEAVMIGDDCRDDVDGAQNIGMLGILVKTGKYKAADEEKINPPPYLTCESFPHAVDHILQHLL---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UGR5-1", "uniprot_id": "HDHD2_MOUSE", "id": "Q3UGR5-1", "name": "Haloacid dehalogenase-like hydrolase domain-containing protein 2", "aln": "MAARRALKAVLVDLNGTLHIEDAAVPGAQEALKRLRATSVMVRFVTNTTKESKKDLLERLKKLEFEISEDEIFTSLTAARNLIEQKQVRPMLLVDDRALPEFTGVQTQ-DPNAVVIGLAPEHFHYQLLNQAFRLLLDG--APLIAIHKARYYKRKDGLALGPGPFVTALEYATDTKAMVVGKPEKTFFLEALRDADCAPEEAVMIGDDCRDDVDGAQNIGMLGILVKTGKYKAADEEKINPPPYLTCESFPHAVDHILQHLL---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H0R4-1", "uniprot_id": "HDHD2_HUMAN", "id": "Q9H0R4-1", "name": "Haloacid dehalogenase-like hydrolase domain-containing protein 2", "aln": "MAACRALKAVLVDLSGTLHIEDAAVPGAQEALKRLRGASVIIRFVTNTTKESKQDLLERLRKLEFDISEDEIFTSLTAARSLLERKQVRPMLLVDDRALPDFKGIQTS-DPNAVVMGLAPEHFHYQILNQAFRLLLDG--APLIAIHKARYYKRKDGLALGPGPFVTALEYATDTKATVVGKPEKTFFLEALRGTGCEPEEAVMIGDDCRDDVGGAQDVGMLGILVKTGKYRASDEEKINPPPYLTCESFPHAVDHILQHLL---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5BJJ5-1", "uniprot_id": "HDHD2_DANRE", "id": "Q5BJJ5-1", "name": "Haloacid dehalogenase-like hydrolase domain-containing protein 2", "aln": "MMARRTLKAVLIDLSGTLHIEDTAVPGAQEALARLRQAPVAVKFVTNTTKECKRTLFERLRGLNFDLQQQEIFTSLTAARNLVEQKAVRPLLMVEDSALEDFTGLETS-DPNAVVIGLAPDHFNYQTLNKAFQLILDG--APLIAIHKARYYKKKDGLALGPGPFVTGLEYATDTKATVVGKPEKGFFLEALRDLNCSPEEAVMIGDDARDDVGGAQNAGMLGILVKTGKYRPADEGKINPPPHLTCASFPEAVNYILDHLLGSK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VLM9-1", "uniprot_id": "Q9VLM9_DROME", "id": "Q9VLM9-1", "name": "Haloacid dehalogenase-like hydrolase domain-containing protein 2", "aln": "----MSIKGALIDLSGTLHVEDEPTPNAVEALKRLRDSGVLVKFVTNTTKDSKATLHERLCRIGFQLDASEIYSSLSAAVSYVENERLNPYYILSEDARQDFPPEDTRRYKDSVVIGLAPKAFNYEQLNEAFNVLLENKNHKLIAVHQGKYYKRAEGLALGPGCFVKGLEFATGRTAKVIGKPNPYFFEGALAGR--DPASCVMIGDDANDDIVGAMSMGMQGILVKTGKYLP--DVKPSPPPTALLENFAEAVDWIIQKNQS--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*..*:**.****:** ..*.* *** *** : * ::*******:.* * *** : *::. .**::**:** . :*.. :.* ::.: * :* :* ::**:****. *:*: **:**.::*:. ***:*:.:***: :******* **..**:**. .* *:***: ** ** . * ..******..**: ** . ** ********* . : * .*** .*..**: *::: ", "identical_positions": 115, "similar_positions": 76, "identity": "43.4%" }, { "cls_id": "homologset.agr.RGD:1308584", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R3W5-1", "uniprot_id": "SEN15_MOUSE", "id": "Q8R3W5-1", "name": "tRNA-splicing endonuclease subunit Sen15", "aln": "MEERSDSEPTPGCSGPGPAPVR---DGGGAHTWAPEDAWMGTHPKYLEMMELDIGDATQVYIAFLVYLDLMESKSWHEVNCVGIPELQLICLLGTEIEGEGLQTVVPTPISASLSHNRIREILKASRKLQGDPELPMSFTLAIVESDSTIVYYKLTDGFMLPDPQNISLRR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K1V3-1", "uniprot_id": "A0A0G2K1V3_RAT", "id": "A0A0G2K1V3-1", "name": "tRNA-splicing endonuclease subunit SEN15", "aln": "MEERSDSEPTPGCSGPGPGPVR---DGGAAHKWAPEDAWMGTHPKYLEMMELDIGDATQVYIAFLVYLDLMESKSWHEVNCVGIPELQLICLLGTEIEGEGVQTVVPTPISASLSHNRIREILKASRKLQGDPELPMSFTLAIVESDSTIVYYKLTDGFMLPDPQNISLRR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8WW01-1", "uniprot_id": "SEN15_HUMAN", "id": "Q8WW01-1", "name": "tRNA-splicing endonuclease subunit Sen15", "aln": "MEERGDSEPTPGCSGLGPGGVRGFGDGGGAPSWAPEDAWMGTHPKYLEMMELDIGDATQVYVAFLVYLDLMESKSWHEVNCVGLPELQLICLVGTEIEGEGLQTVVPTPITASLSHNRIREILKASRKLQGDPDLPMSFTLAIVESDSTIVYYKLTDGFMLPDPQNISLRR", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****.********** **. ** ***.* .*****************************:*********************:********:********:********:**********************:*************************************", "identical_positions": 155, "similar_positions": 10, "identity": "90.64%" }, { "cls_id": "homologset.agr.RGD:1308585", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4AAR5-1", "uniprot_id": "D4AAR5_RAT", "id": "D4AAR5-1", "name": "", "aln": "MLLPPALYSRLAGEPG--AAEPLPVERN-----------PAAG----EAPFRYAPRPVRFPRDHEFFED-----------MLTQVSETPEKSMVPEFTCQVAGCCQVFAAIEDYQHHYHMMHGNTCSFCNRAFPSGHLLDVHILEWHDSLFQILAQRQD--MYQCLVESCPEKFKTSQDRKDHMVRLHLYPADFRFDKPK----------TNRGPAMPAAADTAARALRDDSDAMEVCLEPAAPPPC-----RRTYSHRIPSTVCFGQGAARGFKSTKKKNKHH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P0X2-1", "uniprot_id": "ZN511_MOUSE", "id": "Q6P0X2-1", "name": "Zinc finger protein 511", "aln": "MLLPPALYSRLAGEPG--AAEPLPVERN-----------PAAG----EAPFRFAPRAVRFPRDHEFFEDGDVQRHLYLQDMLTQVSETPEKSMVPEFTCQVAGCCQVFAAIEDYQHHYHMMHGNTCSFCNRAFPSGHLLDVHILEWHDSLFQILAQRQD--MYQCLVESCPEKFKTSQDRKDHMVRLHLYPADFRFDKPK----------TNRGPAMPAAADAATRAPTDDSDAMEICSEPAAPPPC-----RRTYSHRSV-----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NB15-2", "uniprot_id": "ZN511_HUMAN", "id": "Q8NB15-2", "name": "Zinc finger protein 511", "aln": "MQLPPALCARLAAGPG--AAEPLPVERD-----------PAAG----AAPFRFVARPVRFPREHQFFEDGDVQRHLYLQDVIMQVADVPEKPRVPAFACQVAGCCQVFDALDDYEHHYHTLHGNVCSFCKRAFPSGHLLDAHILEWHDSLFQILSERQD--MYQCLVEGCTEKFKTSRDRKDHMVRMHLYPADFRFDKPK----------KSRSPASAEAPGDSG--ERSEGEAMEICSEPVAASPAPAG-ERRIYRHRIPSTICFGQGAARGFKSNKKKTKQC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZZ00-1", "uniprot_id": "ZN511_DANRE", "id": "Q7ZZ00-1", "name": "Zinc finger protein 511", "aln": "-MLQPEIIEFLASTTPQILAKNIPVTENRESKRHDIQQKAEAGEEKAVSPFEFRPQRLRFAVEDEYFEDGDINRHMYLQNIVTSFVDDKQPPTISEFRCHIAGCKQLFDTLEGYEHHYNALHRNVCSNCKRSFPSNRLLEIHILEWHDSLFQIMAEKQC--MYECLVEGCGLKFKTSKERKDHLIRTHSYPADFRFDKSKKIGRTTEKKTQQKKDAHMEVSATVLQQESSESMDFSLTPEPVETEPMQAANLKPRYSYKVPSSICFGQGSVRGFRGRRKK----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V574-1", "uniprot_id": "L2K1_DROME", "id": "Q9V574-1", "name": "Protein lethal(2)k10201", "aln": "MDSEAAGVALLSREQIIRILSEVP------------AG-------------FIKPTDPPAPSLAPFKKLG----------VLVDIDDILGE--------QDAAAARIRDNIDKEQSYS-------CVECRKMLPTAHLLDLHITEQHDCYFAASVERGDKPMFSCFLEECTIKFHTARQRKDHCIITHKLPANYRFDHSK-----------NRGKQKHQGKSKPNSMEVDEVIEETKSLPYVKAFSFGHQTQRSFYTGKDQ-RSGKTLDDVQAMKEAINDILD-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *: . :* . . : : :: .. : : *.. :: :: : : * *.: :*: :**: ** * **. * :: *:.*::* * **:*:::**** : * **::***:.* .: .: . . . : * : ", "identical_positions": 33, "similar_positions": 53, "identity": "11.62%" }, { "cls_id": "homologset.agr.RGD:1308586", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VI94-1", "uniprot_id": "OASL1_MOUSE", "id": "Q8VI94-1", "name": "2'-5'-oligoadenylate synthase-like protein 1", "aln": "MAVAQELYGFPASKLDSFVAQWLQPTREWKEEVLETVQTVEQFLRQENFREDRGPARDVRVLKVLKVGCFGNGTVLRSTTDVELVVFLSCFHSFQEEAKHHQAVLRLIQKRMYYCQELMDLGLSNLSVTNRVPSSLIFTIQTRETWETITVTVVPAYRALGPSCP----SSEVYANLIKANGYPGNFSPSFSELQRNFVKHRPTKLKSLLRLVKHWYQQYVRDKCPRANLPPLYALELLTVYAWEAGTREDANFRLDEGLATVMELLQDHELLCIYWTKHYTLQHPVIEACVRRQLRGQRPIILDPADPTNNVAEGYRWDIVAQRANQCLKQDCCYDNRDSPVPSWRVKRAPDIQVTVQEWGHSDLTFWVNPYEPIKKLKEKIQLSQGYLGLQRLSFQEPGGERQLIRSHCTLAYYGIFCDTHICLLDTISPEIQVFVKNPDGRSHAYAIHPLDYVLNLKQQIEDRQGLRCQEQRLEFQGHILEDWFDFKSYGIQDSVTVILSKTTEGAAPFVPS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3V645-1", "uniprot_id": "OASL1_RAT", "id": "G3V645-1", "name": "2'-5'-oligoadenylate synthase-like protein 1", "aln": "MAVAQELYSFPASKLDSFVAQWLQPTREWKEEVLETVQTVEQFLRQENFRGERGPAQDVRVLKVLKVGCFGNGTVLRSTTDVELVVFLSCFHSFQEEAKHHQAVLRLIQKRMSYCRDLLDLGLSNLSVIEEVPSSLIFTIQTRETWEPITVTIVPAFRALGPSCPN---SAEVYVNLIKANGYPGNFSPSFSELQRSFVKHRPTKLKSLLRLVKHWYQQYVRDKCPRANLPPLYALELLTVYAWEAGTQEDSNFRLDEGLATVMELLQDHELLCIYWTKYYTLQHPVIERFVRRQLKGERPIILDPADPTHNVAQGYRWDIVAQRASQCLKQDCCYDDRDAPVPSWTVKRAPDIQVTVQQWGHPDLILWVNPYEPIKKLKEKIRLSRGYSGLQRLSFQEPGGQRQLIRSQCSLAYYGIFCDTQICLLDTISPEIQVFVKNPDGGSHAYAIHPLDFVLSLKQQIEDRQGLQSQEQQLEFQGRVLEDWFDFKSYGIQDSITIILSRKREGKAPSAPS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q15646-1", "uniprot_id": "OASL_HUMAN", "id": "Q15646-1", "name": "2'-5'-oligoadenylate synthase-like protein", "aln": "MALMQELYSTPASRLDSFVAQWLQPHREWKEEVLDAVRTVEEFLRQEHFQGKRGLDQDVRVLKVVKVGSFGNGTVLRSTREVELVAFLSCFHSFQEAAKHHKDVLRLIWKTMWQSQDLLDLGLEDLRMEQRVPDALVFTIQTRGTAEPITVTIVPAYRALGPSLPNSQPPPEVYVSLIKACGGPGNFCPSFSELQRNFVKHRPTKLKSLLRLVKHWYQQYVKARSPRANLPPLYALELLTIYAWEMGTEEDENFMLDEGFTTVMDLLLEYEVICIYWTKYYTLHNAIIEDCVRKQLKKERPIILDPADPTLNVAEGYRWDIVAQRASQCLKQDCCYDNRENPISSWNVKRARDIHLTVEQRGYPDFNLIVNPYEPIRKVKEKIRRTRGYSGLQRLSFQVPGSERQLLSSRCSLAKYGIFSHTHIYLLETIPSEIQVFVKNPDGGSYAYAINPNSFILGLKQQIEDQQGLPKKQQQLEFQGQVLQDWLGLGIYGIQDSDTLILSKKK-GEALFPAS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: ****. ***:*********** ********::*:***:*****:*: .** :*******:***.********** :****.********** ****: ***** * * .::*:****.:* : :.**.:*:****** * *.****:***:****** * ..***..**** * ****.********.************************: :.***************:**** **.** ** ****::***:** ::*::******:***::.:** **:**: :*********** ***:***********.**********:*: *:.** **** **::**:: *:.*: : *******:*:****: ::** ******** **.:***: *:*:** ****..*:* **:**..*********** *:****:* .::*.*******:*** ::*:*****::*:**:.: ****** *:***:. * * .*", "identical_positions": 350, "similar_positions": 107, "identity": "67.96%" }, { "cls_id": "homologset.agr.RGD:1308588", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4A9V5-1", "uniprot_id": "D4A9V5_RAT", "id": "D4A9V5-1", "name": "Lysyl oxidase homolog 4", "aln": "MMWPPPPTFSVFLLLLLSQVPSSRPQSPGTKKLRLVGPANRPEEGRLEVLHQGQWGTVCDDDFALQEATVACRQLGFESALTWAHSAKFGQGEGPIWLDNVRCLGTEDTLDQCGSNGWGVSDCRHSEDVGVVCHPRRQQGYHSEKVSNALGPQGRRLEEVRLKPILASAKRHSPVTEGAVEVRYEGHWRQVCDQGWTMNNSRVVCGMLGFPSQAPVNSHYYRKVWNLKMKDPKSRLNGLTKKNSFWIHRVDCLGTEPHLAKCQVQVAPGRGKLRPACPGGMHAVVNCVAGPHFQRQKPKPKRKESGAEQELKVRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGAQLGQGLGPIHLSEVRCRGYEQTIGDCLALEGSQNGCQHANDAAVRCNIPDMGFQNKVRLAGGRNSEEGVVEVQVEVNGVPRWGTVCSDHWGLTEAMVTCRQLGLGFANFAIKDTWYWQGTPEAKEVVMSGVRCSGTEMALQQCQRHGP---VHCSHGSGRFSAGVACMNSAPDLVMNAQLVQETAYLEDRPLSMLYCAHEENCLSKSADHMD-----WPYGHRRLLRFSSQIYNLGRADFRPKAGRHSWIWHQCHRHYHSIEVFTHYDLLTLNGSKVAEGHKASFCLEDTNCPSGVQRRYACANFGEQGVAVGCWDTYRHDIDCQWVDITDVSPGDYIFQVVVNPTNDVAESDFSNNMIRCRCKYDGQRVWLHNCHTGDPYRPNAELSLEQEQRLRNNLI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q924C6-1", "uniprot_id": "LOXL4_MOUSE", "id": "Q924C6-1", "name": "Lysyl oxidase homolog 4", "aln": "MMWPQPPTFSLFLLLLLSQAPSSRPQSSGTKKLRLVGPTDRPEEGRLEVLHQGQWGTVCDDDFALQEATVACRQLGFESALTWAHSAKYGQGEGPIWLDNVRCLGTEKTLDQCGSNGWGVSDCRHSEDVGVVCHPRRQHGYHSEKVSNALGPQGRRLEEVRLKPILASAKRHSPVTEGAVEVRYDGHWRQVCDQGWTMNNSRVVCGMLGFPSQTSVNSHYYRKVWNLKMKDPKSRLNSLTKKNSFWIHRVDCLGTEPHLAKCQVQVAPGRGKLRPACPGGMHAVVSCVAGPHFRRQKPKPTRKES-HAEELKVRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGAQLGQGLGPIHLSEVRCRGYERTLGDCLALEGSQNGCQHANDAAVRCNIPDMGFQNKVRLAGGRNSEEGVVEVQVEVNGVPRWGTVCSDHWGLTEAMVTCRQLGLGFANFALKDTWYWQGTPEAKEVVMSGVRCSGTEMALQQCQRHGP---VHCSHGPGRFSAGVACMNSAPDLVMNAQLVQETAYLEDRPLSMLYCAHEENCLSKSADHMD-----WPYGYRRLLRFSSQIYNLGRADFRPKAGRHSWIWHQCHRHYHSIEVFTHYDLLTLNGSKVAEGHKASFCLEDTNCPSGVQRRYACANFGEQGVAVGCWDTYRHDIDCQWVDITDVGPGDYIFQVVVNPTNDVAESDFSNNMIRCRCKYDGQRVWLHNCHTGDSYRANAELSLEQEQRLRNNLI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96JB6-1", "uniprot_id": "LOXL4_HUMAN", "id": "Q96JB6-1", "name": "Lysyl oxidase homolog 4", "aln": "MAWSPPATLFLFLLLLG-QPPPSRPQSLGTTKLRLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWAHSAKYGQGEGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVICHPRRHRGYLSETVSNALGPQGRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGHWRQVCDQGWTMNNSRVVCGMLGFPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGTEPHMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRPPKTKPQRKGS-WAEEPRVRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGLGPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCNVPNMGFQNQVRLAGGRIPEEGLLEVQVEVNGVPRWGSVCSENWGLTEAMVACRQLGLGFAIHAYKETWFWSGTPRAQEVVMSGVRCSGTELALQQCQRHGP---VHCSHGGGRFLAGVSCMDSAPDLVMNAQLVQETAYLEDRPLSQLYCAHEENCLSKSADHMD-----WPYGYRRLLRFSTQIYNLGRTDFRPKTGRDSWVWHQCHRHYHSIEVFTHYDLLTLNGSKVAEGHKASFCLEDTNCPTGLQRRYACANFGEQGVTVGCWDTYRHDIDCQWVDITDVGPGNYIFQVIVNPHYEVAESDFSNNMLQCRCKYDGHRVWLHNCHTGNSYPANAELSLEQEQRLRNNLI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W2C9-1", "uniprot_id": "Q9W2C9_DROME", "id": "Q9W2C9-1", "name": "", "aln": "----------------------------------MCAIEDR------KVLKMGLT-LVCLTLLAIHMADAVVQHRSLEDA-------------------------------------------------------RQERQRLVHRYTKVLNK-----EEGAIRLVGGDNE-----YEGNIEVLHNGKWGAVCDDEWDSTEADIVCRQLGFPGMR---------------RYTRSGFFGPARRR-FWMDNLFCEGHEQELVDCHFEGWGEND-----CEPGEAAGVVCYPPENALIPMATPIIRDE---DLPKYPIHS------------------------------------------RSRLY----------------------------------------------------------VRLRGGRSRIEGRVEVSLDGG---RWGSVCADGWSLLEANVVCRQLGLGYASEAFQTDFFGG--FNVSRPVLSGSECYGNETELADCLHHDASQGIISCHGNRQHVAAVICDYIAPDLVVDYLEIEQTAHLEDRPMLLMQCAMEENCVANEAYQIQRDDPHWRYRSRRLLKFTAAAINAGNADFRPFKEKSQWEWHMCHMHFHSMEVFATFDIFNLRGIKVAQGHKASFCLEDSNCLPGVAKKYNCANYGDQGISINCSDVYLYNLDCQWVDVTDLIPGTYVLKIAINPEFKVAEMNYDNNAAICDLIYTANFARVQNCQLGRP--------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . .: :**: * ** :*:: * .. :: .:* * *:.: . ::.*. ** :: : .. : ** :** ::*:* ***: * .:: :** ****. : .:* : . :.:. **:..: * * * .:..*:.: .. * * * * * . : ..* : . : : ::* *. *: *** *** ** :**.:: . ***:**:: *.* ** *.*******:* * : :: .... *:** .* *.* * :* :*.. : ..** :. *.* * *****:: :::**:*****: : ** ****:::.* ::: * * ****:*:: * *.:**** : .* ** ** *:**:***: :*::.*.* ***:**********:** .*: ::* ***:*:**:::.* *.* :::******:**: ** *:::: :** .*** ::.** * * .: . ::**: * . ", "identical_positions": 183, "similar_positions": 168, "identity": "23.89%" }, { "cls_id": "homologset.agr.RGD:1308589", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q61098-1", "uniprot_id": "IL18R_MOUSE", "id": "Q61098-1", "name": "Interleukin-18 receptor 1", "aln": "MHHEELILTLCILIVKSASKSCIHRSQIHVVEGEPFYLKPCGISAPVHRNETATMRWFKGSASHEYRELNNRSSPRVTFHDHTLEFWPVEMEDEGTYISQVGNDRRNWTLNVTKRNKHSCFSDKLVTSRDVEVNKSLHITCKNPNYEELIQDTWLYKNCK----EISKTPRILKDAEFGDEGYYSCVFSVHHNGTRYNITKTVNITVIEGRSKVTPAILGPKCEKVGVELGKDVELNCSASLNKDDLFYWSIRKEDSSDPNVQEDRKETTTWISEGKLHASKILRFQKITENYLNVLYNCTVANEEAIDTKSFVLVRK-EIPDIPGHVFTGGVTVLVLASVAAVCIVILCVIYKVDLVLFYRRIAERDETLTDGKTYDAFVSYLKECHPENKEEYTFAVETLPRVLEKQFGYKLCIFERDVVPGGAVVEEIHSLIEKSRRLIIVLSQSYLTNGARRELESGLHEALVERKIKIILIEFTPASNITFLPPSLKLLKSYRVLKWRADSP-SMNSRFWKNLVYLMPAKAVKPWREESEARSVLSAP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6A1C2-1", "uniprot_id": "A0A8I6A1C2_RAT", "id": "A0A8I6A1C2-1", "name": "Interleukin-18 receptor 1", "aln": "MHHEELILILCVLVVKSAPKSCIRRSQIHVVEGEPFYLKPCDMSAPMHNNETATMRWFKGNASHGYRELNMRSSPRIAFHGHALEFWPVELEDKGTYFSQVGNDRQNWTLNVTKRNKHSCFSEKLVTNRDVEVKKSLWITCENPSYGELINHTLLYKNCK----EISKTPMILKDAEFGDEGYYSCVFSVHHNGQQYNITKTVNITVIEGNSKITPAIFGSKSAKVGVELGEDVELNCSAVLNRNDLFYWSIRKEDSLDPNVHEDRNE-TTWTFEGKLHASKILRIQKVTEKYLNVLYNCTVANEEATDTKSFILVRK-ETPDIQGHVFMRGITMVVLTSVAAVCVVILCIIYKVDLVLFYRRVAERDETLTDGKTYDAFVSYLRECHPENGEEYTFAVETLPRVLEKQFGYKLCIFERDVVPGGAVVDEIHSLIEKSRRLIIVLSKSYMTNGSRLELESGLHQALVERKIKIILIEFTPASNITFLPPSLKLLKSYRVLRWKADKPLSSKSRFWKNLLYLMPAKAVKPWREESEARPVLSAP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13478-1", "uniprot_id": "IL18R_HUMAN", "id": "Q13478-1", "name": "Interleukin-18 receptor 1", "aln": "MNCRELPLTLWVLISVSTAESCTSRPHITVVEGEPFYLKHCSCSL-AHEIETTTKSWYKSSGSQEHVELNPRSSSRIALHDCVLEFWPVELNDTGSYFFQMKNYTQKWKLNVIRRNKHSCFTERQVTSKIVEVKKFFQITCENSYYQTLVNSTSLYKNCKKLLLENNKNPTIKKNAEFEDQGYYSCVHFLHHNGKLFNITKTFNITIVEDRSNIVPVLLGPKLNHVAVELGKNVRLNCSALLNEEDVIYWMFGEENGSDPNIHE-EKEMRIMTPEGKWHASKVLRIENIGESNLNVLYNCTVASTGGTDTKSFILVRKADMADIPGHVFTRGMIIAVLILVAVVCLVTVCVIYRVDLVLFYRHLTRRDETLTDGKTYDAFVSYLKECRPENGEEHTFAVEILPRVLEKHFGYKLCIFERDVVPGGAVVDEIHSLIEKSRRLIIVLSKSYMSNEVRYELESGLHEALVERKIKIILIEFTPVTDFTFLPQSLKLLKSHRVLKWKADKSLSYNSRFWKNLLYLMPAKTVKPGRDEPEVLPVLSES", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: .** * * :*: *:.:** *.:* ********** *. * *. **:* *:*...*: : *** ***.*:::*. .*******::* *:*: *: * ::*.*** :*******::: **.: ***:* : ***:*. * *:: * ****** * .*.* * *:*** *:******. :**** :*****.***::*..*::.*.::*.* :*.****::*.***** **.:*::** : :*:. ***::* .:* *** ****:**:::: *. **********. . *****:**** : .** **** *: : ** **.**:* :*:**:********:::.******************:**:*** **:***** *******:*******************:*****************:**::* * *******:****************.:::**** *******:***:*:**.. * :*******:******:*** *:*.*. .*** .", "identical_positions": 328, "similar_positions": 128, "identity": "60.41%" }, { "cls_id": "homologset.agr.RGD:1308590", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "F7F8B8-1", "uniprot_id": "F7F8B8_RAT", "id": "F7F8B8-1", "name": "Max-like protein X", "aln": "MTEPG---ASPEDPWVKASL------------------------------------------------------------FFPGLFVESTHKGSVVSRANSIGSTSASSVPNTDDEDS-DYQQES---YKESYKDRRRRAHTQAEQKRRDAIKRGYDDLQTIVPTCQQQ-DFSIGSQKLSKAIVLQKTIDYIQFLHKEKKKQEEEVSTLRKDVTALKIMKVNYEQIVKAHQDNPHEGEDQVSDQVKFNVFQGIMDSLFQSFNASISVASFQELSACVFSWIEEHCEPQTLREIVIGVLHQLKNQLY-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08609-1", "uniprot_id": "MLX_MOUSE", "id": "O08609-1", "name": "Max-like protein X", "aln": "MTEPG---ASPEDPWVKASFADAHAGEGRAGRARARRGSGRRGAPQLSPESPLLSGARGCREDSSHPACAKVEYAYSDNSLDPGLFVESTHKGSVVSRANSIGSTSASSVPNTDDEDS-DYQQEA---YKESYKDRRRRAHTQAEQKRRDAIKRGYDDLQTIVPTCQQQ-DFSIGSQKLSKAIVLQKTIDYIQFLHKEKKKQEEEVSTLRKDVTALKIMKVNYEQIVKAHQDNPHEGEDQVSDQVKFNVFQGIMDSLFQSFNASISVASFQELSACVFSWIEEHCEPQTLREIVIGVLHQLKNQLY-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UH92-1", "uniprot_id": "MLX_HUMAN", "id": "Q9UH92-1", "name": "Max-like protein X", "aln": "MTEPG---ASPEDPWVKASPVGAHAGEGRAGRARARRGAGRRGASLLSPKSPTLSVPRGCREDSSHPACAKVEYAYSDNSLDPGLFVESTRKGSVVSRANSIGSTSASSVPNTDDEDS-DYHQEA---YKESYKDRRRRAHTQAEQKRRDAIKRGYDDLQTIVPTCQQQ-DFSIGSQKLSKAIVLQKTIDYIQFLHKEKKKQEEEVSTLRKDVTALKIMKVNYEQIVKAHQDNPHEGEDQVSDQVKFNVFQGIMDSLFQSFNASISVASFQELSACVFSWIEEHCKPQTLREIVIGVLHQLKNQLY-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N6M0-1", "uniprot_id": "A0A8M1N6M0_DANRE", "id": "A0A8M1N6M0-1", "name": "Max-like protein X", "aln": "MTENS---ASPEDPWLKQTDG-----------------------------------------------------TFSDNGFDHSFFAESARKGSLVSRANSIGSTSASSVPNTDDEDS-DNRHETP--YKESYKDRRRHAHTQAEQKRRDAIKKGYDDLQSIVPTCQQQSDFSMATQKMSKATVLQKTIDYIQFLHKEKKKQEEDVSTLRKEVMALKIMKTNYEHIVKAHQNNPQQGSEQVSDQVKFSVFQSIMDSLFQSFSASVSVSSFQELSACVFSWIEEHCKPQTLREFVVTVLQQVNGQLY-----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VB47-1", "uniprot_id": "Q9VB47_DROME", "id": "Q9VB47-1", "name": "", "aln": "MSDNNNALATKEDVFGMEHDQ-----------------------------------------------------------------DHTSKHYSRCSSAGSTHTPNSSAHNSDDDDDSGDARHSAAANSTLSYKERRREAHTQAEQKRRDAIKKGYDSLQELVPRCQPN---DSSGYKLSKALILQKSIEYIGYLNQQKLKQEDEGSALQKEVTALRIIKNGYENMLQHQQANPGPEEARLTDEAKFQVFQAIMEEMFETFQH-IPMENFKQLTTGIIPWLEEHCKPHILRNILSRTLQQMAQEAMEKQELQAMEQESSEGFS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:: . *: ** : .:::: * * *.* :..:*: . **:** * ::.: . ***:***.**************:***.** :** ** : . . *:*** :***:*:** :*:::* ***:: *:*:*:* **:*:* .**:::: :* ** . :::*:.**.***.**:.:*::*. :.: .*::*:: ::.*:****:*: **::: .*:*: : ", "identical_positions": 93, "similar_positions": 87, "identity": "28.79%" }, { "cls_id": "homologset.agr.RGD:1308591", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9H6P5-1", "uniprot_id": "TASP1_HUMAN", "id": "Q9H6P5-1", "name": "Threonine aspartase 1", "aln": "MTMEKGMSSG---------EGLPSRSSQVSAGKIT------AKELETKQSYKEKRGGFVLVHAG------AGYHSESKAKEYKHVCKRACQKAIEKLQAGALATDAVTAALVELEDSPFTNAGMGSNLNLLGEIECDASIMDGKSLNFGAVGALSGIKNPVSVANRLLCEGQKGKLSAGRIPPCFLVGEGAYRWAVDHGIPSCPPNIMTTRFSLAAFKRNKRKLELAERVDTDFMQLKKRRQSSEKEND---SGTLDTVGAVVVDHEGNVAAAVSSGGLALKHPGRVGQAALYGCGCWAENTGAHNPYSTAVSTSGCGEHLVRTILARECSH-ALQAEDAHQALLETMQNKFISSPFLASEDGVLGGVIVLRSCRCSAEPDSSQNKQTLLVEFLWSHTTESMCVGYMSAQDGKAKTHISRLPPGAVAGQSVAIEGGVCRLESPVN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8R1G1-1", "uniprot_id": "TASP1_MOUSE", "id": "Q8R1G1-1", "name": "Threonine aspartase 1", "aln": "MIMEKGMNSG---------EGLPSRSSQASAAKVT------VKELETQQPCKEKRGGFVLVHAG------AGYHSESKAKEYKHVCKRACQKAIEKLQAGALATDAVAAALVELEDSPFTNAGIGSNLNLLGEIECDASIMDGKSLNFGAVGALSGIKNPVSVAHRLLCEGQKGKLSAGRIPPCFLVGEGAYRWAVDHGIPSCPPSTMTTRFSLAAFKRNKRKLELAERVETDFIQLKRRRQSSAKEND---SGTLDTVGAVVVDHEGNVAAAVSSGGLALKHPGRVGQAALYGCGCWAENTGAQNPYSTAVSTSGCGEHLVRTILARECSH-ALQAEDAHQALLETMQNKFISSPFLACEDGVLGGVIVLRSCRCSSESDSSQDKQTLLVEFLWSHTTESMCVGYMSAQDGKAKTHISRLPPGAVAGQSVAIEGGVCRLESPVN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0M8H7-1", "uniprot_id": "A0ABK0M8H7_RAT", "id": "A0ABK0M8H7-1", "name": "Threonine aspartase 1", "aln": "MVPQARVASSPHRTGRRVWRRLPSRAQGSTDSRVLNRGHAWARQFPWLWSSRSASRAVQSQATGNSRPPGAGYHSESKAKEYKHVCKRACQKAIEKLQAGALATDAVMAALVELEDSPFTNAGVGSNLNLLGEIECDASIMDGKSLSFGAVGALSGIKNPVSVAHRLLCEGQKGKLSAGRIPPCFLVGEGAYRWAVDHGIPSCPPSTMTTRFSLAAFKRNKRKLELAERVETDFIQLKRRRQSSAKEND---SGALDTVGAVVVDHEGNVAAAVSSGGLALKHPGRVGQAALYGCGCWAENTGAHNPYSTAVSTSGCGEHLVRTILARECSH-ALQAEDAHQALLETMQNKFISSPFLASEDGVLGGVIVLRSCRCPSESDPSQDKQTLLVEFLWSHSTESMCVGYMSAQDGKAKTHISRLPPGAVAGQSVAIEGGVCRLESPVN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VUX9-1", "uniprot_id": "Q9VUX9_DROME", "id": "Q9VUX9-1", "name": "", "aln": "------------------------------------------------------MAGFVAVHTG------AGNCID--ETKYQRVIKEACLRATEILRNGGSAVDACEAAIVRLENCGYTNAGYGSNLCMDGSVQCDAAIMDGSTLNFGACTNVSRVKNPIQLARR-ICDAQSSPQLLERIPPMILAGTGAEHYADEVGCSMVEPGVLISSKAKFQFNHYKSKYDLVVNSRLGKATSEESVQVPEPGNEVELAAALDTVGAVCVDGAGNTAAGCSSGGILLKVPGRVGQAATYGAGCWATDT---DELAIATCTTGNGEYLMKTLLAREICHGAFSSDCAVTSLHKTFKQKFLDSPLLPRQQDLYAGALTLLYYPGQSSG-----------EVMWSHTTQSFCVGYMATNQRVPKFVHSPLPTYSVPGRSCVVNGHNFHLRI---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. :* ** : .:*::* *.** :* * *: *. *.** **:*.**:. :**** **** : *.::***:****.:*.*** :* :***:.:*.* :*:.*.. **** :*.* ** ::* : * . *. : : : *:: * * :*. . . :. * . *: :.:******* ** **.**. ****: ** ******** **.**** :* : : *..*:* **:*::*:**** .* *:.:: * :* :*:::**:.**:*. ::.: .*.:.* :. *.:***:*:*:*****:::: .* * **. :*.*:* .::* :*. ", "identical_positions": 142, "similar_positions": 117, "identity": "31.91%" }, { "cls_id": "homologset.agr.RGD:1308593", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5VUJ9-1", "uniprot_id": "DRC8_HUMAN", "id": "Q5VUJ9-1", "name": "Dynein regulatory complex protein 8", "aln": "MLGPGQVRLRPRVWRDKAGGRVADGASGLPPARGSWRETGTGRALGASSPPRPAQGSSSPGIQSGPSSRPGSPRGAEQAGTPRPRLSLGISQATGSAARWRTRRTGKGLGYNSDEIRPRTLLIEHLMEGGRRDHHTMTVLWGTQEIIVAEFHKKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIAEVEEEEPTGYIRFEKFLPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKYMTEE------------------------------------------DGVSLRRPG------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P370-1", "uniprot_id": "A0A8M1P370_DANRE", "id": "A0A8M1P370-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------MADK---YN-------------------------------AENIIIETQKRIGNAFDVFDHESNKTVDVREIGTIIRSLGCFPSEAELHDIISELEEEEPTGFVRYEKFLPTMTKILLERKFRPITEDLLIQAFEVLDQQKKGHLEPAELAKYLTQEG---------------EPFTQEEMDEMLSAAVDPDKNVIFYKDFVSMMTYDDTR---------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8I5ZXW0-1", "uniprot_id": "A0A8I5ZXW0_RAT", "id": "A0A8I5ZXW0-1", "name": "", "aln": "------------------------------------------------------MAASESQKLLVPSFTDSSEVFCSCLQTHQKRTSDPITDGCELPCSCWELNSGPL----------------------------------EEQSVLLTTEPSLQPEISNFISQPAECCNYREIGTIIRSLGCSPTEGELHDFIAEVEEEEPTGYIRFEKFIPVMTTVLLEKRYRPIAEDVLLRAFEVLDPTKRGFLTKDELVKYMTEEGVLFPWRLPLELELHGEPFSQEEMEEMLSAAIDPESNTINYRDYITMMVIDEN----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQ46-1", "uniprot_id": "DRC8_MOUSE", "id": "Q9CQ46-1", "name": "Dynein regulatory complex protein 8", "aln": "------------------------------------------------------MAEERD--------AEGTEALIAEL--HKK-----IKDAFEV-----------------------------------------------------------------FDHESNNTVDVREIGTIIRSLGCCPTEGELHDFIAEIEEEEPTGYIRFEKFIPVMTRALVERRYRPAAEDILLRAFEVLDPAKRGFLTKDELVKYMTEE---------------GEPFSQEEMEEMLSAAIDPESNTINYRDYITMMVVDEN----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A1ZBR3-1", "uniprot_id": "A1ZBR3_DROME", "id": "A1ZBR3-1", "name": "EF-hand domain-containing protein", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------MDMDLNNDLEKRISDAFCVFDHHGDKFIDVREVGTVLRLLGCVPTEEEVNEVISATESEETSGEVHLTKFLPHVSQLLMERKMEPAPPEKILQAFKILDPENKGYLTKESFGKLMMEEG---------------EPFTQEEMDEMWPVAIDPISGHIPYEFYLNQL----MVYL-------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W2L0-1", "uniprot_id": "Q9W2L0_DROME", "id": "Q9W2L0-1", "name": "EF-hand domain-containing protein", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------MEVGVTLNNELEEKISEAFCIFDTHGDKYIDSRNVGNVLRFLGCAPTEKEVEDVIKATDSVDYPGEAHLVKFMEHVSKLLMDRQMEPASSEKLLEAFETLDPENKKYLTKEYFGKLMAEEG---------------EPFSAEELDAMWPVAIDPITGHIPYTFYINQLRHKPDIYEIAEVIKEELAQAEKEKGKKPQQPLF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . : : *::*.::* *** *:* *:.:.* :. : .* : **: :: *:::: .* . : ::.**: ** :: .* : * : :* :. ", "identical_positions": 23, "similar_positions": 40, "identity": "6.74%" }, { "cls_id": "homologset.agr.RGD:1308595", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K0Q8-1", "uniprot_id": "A0A0G2K0Q8_RAT", "id": "A0A0G2K0Q8-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKLAVLPWILMLLSTIPGPG--LTAGTPGS---CSLRCGVQDEICSCHPTCS------------------------------GLGTCCKDFLNYCLEISPSSGSMMGGKDFVVQHLKWTDSITS-VICRFKESIQTLGYVDDLKQVHCISPLLYESGHIPFTISMDNGLSFPHAGTWLAAHPYKVSESEKSQLVNETHWQYYGTSDTGGNLSLTWNTSALPTRTVTIELWGYEETGTPYTGNWTAKWSYLYPLATNIPNTGFFTFTP-----KPAPPQYQRWRVGALRIIGSKNYAGEQDVLALWTNDHALAWHLGDDFRADS-VAWAREQCLTWEALEDQLPNFLTELPDCPCTLAQARADSGRFFTDYGCDIEHGSVCTYHPGAVHCVRSVQASPMYGSGQQCCYTASGTQLLTSDSTSGSTPDRGHDWGAPPYRSPPRVPGMSHWLYDVISFYYCCLWAPECPR-----YMKRRPSSDCRSYRPPRLASAFGDPHFVTFDGTSFSFSGNGEYVLLETLETAAAVKDLRVQGRAQPGRMPNGTQARGTGLTAVAVQEDKSDVIEVRVADGSQ----VLEVLLNQKLLSFTEQNWMDLKGMFLSVAS------QDKVSIMLSSGAGLEVGVQGPFLSVSILLPEKFLSHTRGLLGTLNDNPEDDFTLRNGHVLPPNATAQQ--LFQFGANWAISN------ASSLFTYDSRPLVNQFLNGPKHDPNFKPLFPDETTLSPSQAEDLARLCESDHFCVLDVISTGDPSVGNATR-IAHQLHQHRLKSLQPVVSCGWLPPPVNGHKEGLKYLEGSTVRFGCNSGYSLAGPESSTCRADGTWSSPTP---ECQPGRNYTVLLSIIFGGLAIVALISIVFMLLHRRRKSNRNLWSSQP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DBX3-1", "uniprot_id": "SUSD2_MOUSE", "id": "Q9DBX3-1", "name": "Sushi domain-containing protein 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKLALLPWILMLLSTIPGPG--FTAGAQGS---CSLRCGAQDGLCSCHPTCS------------------------------GLGTCCEDFLDYCLEILPSSGSMMGGKDFVVQHLKWTDPTDG-VICRFKESIQTLGYVDDFYQVHCISPLLYESGYIPFTISMDNGRSFPHAGTWLAAHPYKVSESEKSQLVNETHWQYYGTSDTRGNLNLTWDTSALPTPAVTIELWGYEETGKPYSGNWTSKWSYLYPLATNIPNTGFFTFTP-----KPASPQYQRWKVGALRISSSRNYPGEKDVRALWTNDHALAWHLGDDFRADS-VAWARAQCLAWEALEDQLPNFLTELPDCPCTLAQARADSGRFFTDYGCDIEHGSVCTYHPGAVHCVRSVQASPRYGSGQQCCYTAAGTQLLTSDSTSGSTPDRGHDWGAPPYRTPPRVPGMSHWLYDVISFYYCCLWAPECPR-----YMKRRPSSDCRNYRPPRLASAFGDPHFVTFDGTSFSFSGNGEYVLLET-----TLSDLRVQGRAQPGRMPNGTQARGTGLTAVAVQEDNSDVIEVRLAGGSR----VLEVLLNQKVLSFTEQNWMDLKGMFLSVAA------QDKVSIMLSSGAGLEVGVQGPFLSVSILLPEKFLTHTRGLLGTLNNNPRDDFTLRNGQVLPLNASAQQ--VFQFGADWAVSN------TSSLFTYDSWLLVYQFVYGPKHNPNFKPLFPDETTLSPSQTEDVARLCEGDRFCILDVMSTGSSSVGNATR-IAHQLHQHRLKSLQPVVSCGWLPPPANGHKEGLRYLEGSVVRFSCNNGYSLVGPESSTCQADGKWSMPTP---ECQPGRSYTVLLSIIFGGLAIVALISIIYMMLHRRRKSNMTMWSSQP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UGT4-1", "uniprot_id": "SUSD2_HUMAN", "id": "Q9UGT4-1", "name": "Sushi domain-containing protein 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKPALLPWALLLLATALGPGPGPTADAQES---CSMRCGALDGPCSCHPTCS------------------------------GLGTCCLDFRDFCLEILPYSGSMMGGKDFVVRHFKMSSPTDASVICRFKDSIQTLGHVDSSGQVHCVSPLLYESGRIPFTVSLDNGHSFPRAGTWLAVHPNKVSMMEKSELVNETRWQYYGTANTSGNLSLTWHVKSLPTQTITIELWGYEETGMPYSQEWTAKWSYLYPLATHIPNSGSFTFTP-----KPAPPSYQRWRVGALRIIDSKNYAGQKDVQALWTNDHALAWHLSDDFREDP-VAWARTQCQAWEELEDQLPNFLEELPDCPCTLTQARADSGRFFTDYGCDMEQGSVCTYHPGAVHCVRSVQASLRYGSGQQCCYTADGTQLLTADSSGGSTPDRGHDWGAPPFRTPPRVPSMSHWLYDVLSFYYCCLWAPDCPR-----YMQRRPSNDCRNYRPPRLASAFGDPHFVTFDGTNFTFNGRGEYVLLEA-----ALTDLRVQARAQPGTMSNGTETRGTGLTAVAVQEGNSDVVEVRLANRTG----GLEVLLNQEVLSFTEQSWMDLKGMFLSVAA------GDRVSIMLASGAGLEVSVQGPFLSVSVLLPEKFLTHTHGLLGTLNNDPTDDFTLHSGRVLPPGTSPQE--LFLFGANWTVHN------ASSLLTYDSWFLVHNFLYQPKHDPTFEPLFPSETTLNPSLAQEAAKLCGDDHFCNFDVAATGSLSTGTATR-VAHQLHQRRMQSLQPVVSCGWLAPPPNGQKEGNRYLAGSTIYFHCDNGYSLAGAETSTCQADGTWSSPTP---KCQPGRSYAVLLGIIFGGLAVVAAVALVYVLLRRR-KGNTHVWGAQP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q0KHY3-3", "uniprot_id": "MESH_DROME", "id": "Q0KHY3-3", "name": "Protein mesh", "aln": "MRFKLFVVCALACGFMAFVLANENISTEEFEDQIINAVPEPVKVTKPKAQAEFVEVPKATPAPKKAEADNPKTKPLALQKPTLIPVVHVSSRGTDDILTVAGLKPEKMFGALIMPNDYLGELYDVDNSGYNWDPNNNVAPPTTYSTAAGGYTITAARLAELRSNFMYWYFDKDMYGGRGDYQFDIHASMTQLHKNLNFQLPFYGFRFNYTRLSLNGYLEFSDPPEYLTYPLVFPIKDWPAKRDPSFMGIFFSKCRVGRIYPSDIDQRTPGVYFRVERDLMGRTDRFGVEVRERTMWDIRQGVVGADTFIPKHVVIATWKNVSFAGGIDNSLYTTNTFQMVLATDEVYTYIIFNYAVLNWLSHTEAGGDTTKGEGGVPAYVGFNAGNGTQAYEYNPYSQNMVIRDLANRGWANGFPGRHIFRVDEQILIGSCNKDIDAALLPLTFAPESGNMLGG---QVVNITGPCFDPAIRVTCHFDTESVLGTYVDRNRVICVQPYLKAEGYIRFQISVG-TQRFKWRGKYFVETPAAATEKIFFTTDDVHKKNPAEIRITWNQYNLTSNANAN----VMISLWGYRET------KIEPQLEYIDVIEASYSNSGSYVITPSNYINRNNINRDMQFGFLQINLTQPDQYSGLAISPVLWSRPIPLAWYMAPQWERQHGKRWARALCDNWIRADRFLRNFAADLPLCPCTLDQAVLDKGRFRPDRECDKDSNPSCLRHRGAIHCVVSGTP-VAQGAEQQCCYDRYGFLMLTYDQMWGSRPRRVHNLGKMPWNEASKVPSLSMWFHDMRPFYSCCYWQEEQAVGCETYRFERRPSQDCVAYQAPGIAGVFGDPHFVTFDGTAYTFNGLGEFVLARSVD---ESNKFEVQGRFEQLPVNYYGEVKATQLTAVAMRGNTTTTIEVRLRPLHARWRYRLDVLADGRRVYFDRESLKFQHFDGVTVYTPTYLLNQSQVVVQFDAGIGVEVVENEGYMTGRVFLPWKFINKTAGLFGNWSFNKLDDFMLPNGQVAQLNLNDLRSIHTNFGIKWMLTDREVPGVGAALFKREFGRMSGYYANATFQPNYVLDPADFLPANRSYDLERAEELCGECMQCQYDYAMTLNRDLAHFTKNYYDTIVNMQAENAVRVVSCGVLQTPRFGRKLSFDFMPGAKVSFECNEGFILIGDQRRECLSNGLWNIPEYGYTECLREVYYTRRVAFIAIGIIFLVICPLMLCIVCGVYRYRQKQLKEDPQWQMPMLPRSRASSARNLRTLNYDDDSDTDASTLKKSRSYDKVYRTNEPLPGKPQIDFPAKKWDLDENDEDVTSSEGEKPKQLGRRSLHSASGTELDQHGSPVDGDHPDEDDDFDEADVHTGTTHPVGYHQPLSPEEADQLHRQQYSPTFSGLDSRTSGASSINYTPQAATQNRFGGVPVLPSNTQYYSRPPSSVNTVPLRTAPTPLTQDTGLPSPPLATSPTPSVQKSTEV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :: : :: : .* * . .:..* . :* .. * . * * : * **.*:** * ::. . . : . :: ..** . :* *:.* * .* * * :*:. * *.::. * .: : : : * .: .** ...: : *.****.** : .: .*: : : .*:* :.:** : :: . :.: . :*.* .**:. .***::. ::. : *** * * : * ** :** ***** ** *.*** .* ** : .. * * **:*** * . *: ***** * :** *. ** * * *: * *:. ..:**.:* *::*: .** ** * : . ::****.** *:.* :*..************ ::*.* **:** .: ..:.**.* : : :.:.* *****:: ..: .:***: *:** : . : * .:. : ::* : .:* : : :* *:** : ::: ::** **:.:* **:*. . : *** * .*:* . . . ** .* : : ::*:. : : : . : . .: . : .** * * * . . . *: . : : : :. ***** * .* *:* . :: *: : * *:.*: * * : * ::* *. * :* *: :.:* *: .:. .:: :: : . :* ", "identical_positions": 205, "similar_positions": 245, "identity": "13.93%" }, { "cls_id": "homologset.agr.RGD:1308596", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GJ20-1", "uniprot_id": "A0A8I6GJ20_RAT", "id": "A0A8I6GJ20-1", "name": "Kinesin-like protein KIF23", "aln": "MRRAGAHLGLQRRRRALFRLSPGPRGRSLHGLVPASPAPVGARRPARASGQHGDCGHEVGAKMPRKPV----IKKGSQTNLKDPVGVYCRVRPLSFPDQECCVEVVNSTTVQLHTPEGYRLNR---NGDYKETQYSFKRVFGTHTTQKELFDVVASPLVDDLIHGKNGLLFTYGVTGSGKTYTMTGSPGSGGLLPRCLNMIFNSIGSFQAKRFVFKSNDRNSMEIQCEVDALLERQKRE--AMP-IPKTPSSKRQADPEFADMINVQEFCKAEEVDEDSVYGVFVSYIEIYNNYLYDLLEEVQFDPIKPKL---------------PQSKMLREDKNHNMYVAGCTEVEVKSTEEAFEVFWRGQKKRRIANTHLNRESSRSHSVFSIKLVQAPLDADGDNVLQEKEQITISQLSLVDLAGSERTNRTKAEGNRLREAGNINQSLMTLRTCMEVLRENQMYGTN----KMVPYRDSKLTHLFKNYFDGEGKVRMIVCVNPKAEDYEESLQVMRFAEVTQEVEVARP-VDKAICGLTPGRRYRN-----------LPRAGPVGDE-PLT-EEILQSFPPLPPCKLLDVNDEETLPRLMDALEKRHRLRQLMTEELNKQCVAFKALFKEFDNSLSNKENYIQE---KLNEKEKVISGQKSEIERLEKKNKTLEYKIEILEKTTTIYEEDKRNLQQELESQHQKLQREFSDKRRLEARLQGMVTETTMKWQKECERRVAATQLEMQNKLWVKDEKLKQLKAIVTEPKPE--KPERPSRDRDREKIIQRSVSPSPVPLSSN-NIAQISNGQQLMSQPQLHRRSNSCS---SISVASCISEWEQKLSPFSTPVNVTSLARHRQQEPGQSKACMVSDRRRGMCWTEGREMVPTFSSEIGVQEDHCRR--------NTPIPVRHRRSRSAG-SRWVDHKPASNVQTETVMQPHVPHAITVSVA---NEKALAKCEKYMLTHQELASDGEIQTKVIKGDVYKTRGGGQSVQFTDIETLKQESPTGSRKRRSSTLAPAQPDGTESEWTDVETRCSVAVEMRAGSQLGPGYQHHAQPKRKKP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q5G3-1", "uniprot_id": "KIF23_MOUSE", "id": "E9Q5G3-1", "name": "Kinesin-like protein KIF23", "aln": "-------------------------------------------------------MKSAKAKTVRKPV----IKKGSQTNLKDPVGVYCRVRPLSFPDQECCVEVINSTTLQLHTPEGYRLNR---NGDYKETQYSFKRVFGTHTTQKELFDVVANPLVDDLIHGKNGLLFTYGVTGSGKTYTMTGSPGSGGLLPRCLNMIFNSIGSFQAKRYVFKSNDRNSMEIQCEVDALLERQKRE--ALP-IPKTPSSKRQADPEFADMINVQEFCKAEEVDEDSVYGVFVSYIEIYNNYIYDLLEEVQFDPIKPKL---------------PQSKTLREDKNHNMYVAGCTEVEVKSTEEAFEVFWRGQKKRRIANTHLNRESSRSHSVFSIKLVQAPLDADGDNVLQEKEQITISQLSLVDLAGSERTNRTKAEGNRLREAGNINQSLMTLRTCMEVLRENQTYGTN----KMVPYRDSKLTHLFKNYFDGEGKVRMIVCVNPKAEDYEESLQVMRFAEVTQEVEVARP-VDKVICGLTPGRRYRN-----------LPRGGPVGDE-PLVPEVILQSFPPLPPCKLLDINDEETLPKLADTLEKRHHLRQLMTEDLNKKCLAFKALLKEFDNSLSNKENYVQE---KLNEREKVISGQKLEIERLEKKNKTLEYKIEILEKTTTIYEEDKRNLQQELESQNQKLQRQFSDKRRLEARLQGMVTETSMKWQKECERRVAATQLEMQNKLWVKDEKLKQLKAIVTEPKPE--KPERPSRERDREKIIPRSVSPSPLPLSSN-NIAQISNGQQLMSQPQLHRRSNSCS---SISVASCISEWEQKLSPFSTPVNVTSLARHRQQEPGQSKTCIVSDRRRGMCWTEGREMVPTFSSEIGVEEDHCRR--------NTPIPVRHRRSRSAG-SRWVDHKPASNVQTETVMQPHVPHAITVSVA---NEKALAKCEKYMLTHQELASDGEIQTKVIKGDVYKTRGGGQSVQFTDIETLKQELPTGSRKRRSSTLAPAQPDGTESEWTDVETRCSVAVEMRAGSQLGPGYQHHAQPKRKKP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q02241-1", "uniprot_id": "KIF23_HUMAN", "id": "Q02241-1", "name": "Kinesin-like protein KIF23", "aln": "-------------------------------------------------------MKSARAKTPRKPT----VKKGSQTNLKDPVGVYCRVRPLGFPDQECCIEVINNTTVQLHTPEGYRLNR---NGDYKETQYSFKQVFGTHTTQKELFDVVANPLVNDLIHGKNGLLFTYGVTGSGKTHTMTGSPGEGGLLPRCLDMIFNSIGSFQAKRYVFKSNDRNSMDIQCEVDALLERQKRE--AMP-NPKTSSSKRQVDPEFADMITVQEFCKAEEVDEDSVYGVFVSYIEIYNNYIYDLLEEVPFDPIKPKP---------------PQSKLLREDKNHNMYVAGCTEVEVKSTEEAFEVFWRGQKKRRIANTHLNRESSRSHSVFNIKLVQAPLDADGDNVLQEKEQITISQLSLVDLAGSERTNRTRAEGNRLREAGNINQSLMTLRTCMDVLRENQMYGTN----KMVPYRDSKLTHLFKNYFDGEGKVRMIVCVNPKAEDYEENLQVMRFAEVTQEVEVARP-VDKAICGLTPGRRYRN-----------QPR-GPVGNE-PLVTDVVLQSFPPLPSCEILDINDEQTLPRLIEALEKRHNLRQMMIDEFNKQSNAFKALLQEFDNAVLSKENHMQG---KLNEKEKMISGQKLEIERLEKKNKTLEYKIEILEKTTTIYEEDKRNLQQELETQNQKLQRQFSDKRRLEARLQGMVTETTMKWEKECERRVAAKQLEMQNKLWVKDEKLKQLKAIVTEPKTE--KPERPSRERDREKVTQRSVSPSPVPLSSN-YIAQISNGQQLMSQPQLHRRSNSCS---SISVASCISEWEQKIPTYNTPLKVTSIARRRQQEPGQSKTCIVSDRRRGMYWTEGREVVPTFRNEIEIEEDHCGRLLFQPDQNAPPIRLRHRRSRSAG-DRWVDHKPASNMQTETVMQPHVPHAITVSVA---NEKALAKCEKYMLTHQELASDGEIETKLIKGDIYKTRGGGQSVQFTDIETLKQESPNGSRKRRSSTVAPAQPDGAESEWTDVETRCSVAVEMRAGSQLGPGYQHHAQPKRKKP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PLX5-1", "uniprot_id": "A0A8M9PLX5_DANRE", "id": "A0A8M9PLX5-1", "name": "Kinesin-like protein", "aln": "------------------------------------------------------MIRQAKGKTPRRPP----PKKPS-NNQKDPVGVYCRVRPLGAEDEECCIEVISNTTIQLHAPDGLKANR---NGEFKETQYSFKKVFGIKTTQRELFEDVAKPLAQDLIHGKNGLLFTYGVTGSGKTHTMTGSPGQGGLLPRSLDMIFNSIGPYQAKRYVFKPDDKNGMEVQNQVDALLDRQKRD--SQTSVPKTPNTRR-VDPEFADMISPEEACKAEGVDEDSSYSVFVSYIEIYNNYIYDLLEETPFDPIKPKWNGAGTPVRNITEFIPPQSKILREDQNHNMYVAGCTEVEVKSTEEAFEVFWRGQKKRRIANTQLNRESSRSHSVFIVKLAQAPLDADGDNVLQDKNQVNVSQLCLVDLAGSERTSRTRAEGNRLREAGNINQSLMTLRTCIEVLRENQMCGTN----KMVPYRDSKVTHLFKNYFDGEGKVRMVVCVNPKADDYEETLLVMRFAEMTQEVEVARP-VDRPICGFAAGRRQRNQAFKEELTRRLEERGGPVDGDCPTVLNQLLQAFPPLPPCEISGPNDDVTLPRLIEALEKRHKIRQMMIEEYNKTATMLKSVLQEQDGNILSKENVIQEQRGKLGEKDKMLQNQKNEIDRLEKKSKMLEYKIDILQKTTNIYEEDKRSLQNELESREQRLQREMSEKRRIEARMQGMVSDTKLKWEKECERRVNAKQLEMQNKLWVKDEKLKQLKAIVTEGKTENRQPQRPSREKDK-VPPKRSASPSPAPSSYNGSQSSLSSLEPIYNFSQTVRPDTHFPRAGSVSVASCISEWEQGVP-QSRRQGSQSPPDCRNRTQGLPDS---LSRRRGRCWAR---EVPVQPADVDLEETVHWT--------GPPVRPLHRRSHSAGGERWVDHKPTTNVDLDTVMQPNIPNAIKVNAP---NEKALSKCDKYVLTHQEVASDGEIQTKLIKGEVFKTRGGGQSVQFTDIETLKQETPVAASRKRRSSESGPDSEPMEGNWTDVETRCSVAVEMRAGSNLGPGYQHHGYTKRRKP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VZF5-1", "uniprot_id": "Q9VZF5_DROME", "id": "Q9VZF5-1", "name": "Kinesin-like protein", "aln": "------------------------------------------------MKAVPRTPMRVVPKTPRVHQTVEKQRRDTSDKARDPVNVFCRVRPLQSDADLTSLRVKNSTTIALNPQDQLLQHHKPHNGAQREVQYIFKHVFQPDATQQDVYAAVAQPLVENLLKGRNSLLFTYGVTGSGKTYTMTGNLRHRGIMPRCLDVLFRTISDYQAKKFVFKPDKLNGFEILSEEDALLERQHEMNQRFAGSGRFAFRHKDSDPEIASQAS-VEPIPLLGLDEDNMYSVFVTYIEIYNNSVYDLLEDSGIQKT-------------------LQSKIIREDANRHMFVHGVTEVEVKTVEDALEVFQMGQKRKRMGHTVLNAESSRSHSVFNIRLVQAPTDSQGENVVQDRQNITVSQLSLVDLAGSERSSRTKNTGVRLREAGNINNSLMTLRTCLEYLRENQLAASNGLAPKKVPYRDSKITHMFKNYFDGEGQVSMIVCINPRIEDYDENMQVMKFAEMTQEVQIARATPMKQDLGLTPGRRKANKLFKIAVNN-LNELGIPEAKDLEVDVGLVYSLGPDFPAYEMDSPEAQIKIRELMHYLEQRIEKRKKLRANLDIKCDSFRQMLMNLD-----RDNLQLR--TELASLKAVYKQERDRSAALEKKVRIHESSIDVLNNTLSKQERQIEELTFKLNEKENMLTQKEHEKEKQKKKFSSKLAVESDKNKREFELKLREQRVKLQERMRIKDEKLRLVSNILQ------------------------SEDLPSLPRSQS--------SENILN--------------------------EKDRGAYTARTEESSVPATR--------TDIYATPRHG----------------------------------AAAANNRHRRSRSAG-DKWLEHRAANPVPLGTIMQPYLKNRKSVTKLTDLKELTAHGTTKYCLVSQDADTDGDVETKLYKGNVIPTCGGGAQVVFNDVECLKQKSPVHSPTRKRPS------NGNISALGGGAVPSTVTSAQDVASRCNLGIEGHSSKKSKI-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * * :: : : :***.*:****** : .:.* ..**: *:. : :: ** :*.** **:** .:**:::: **.**.::*::*:*.*************:****. *::**.*:::*.:*. :***::***.:. *.::: : ****:**:. . : . :: ***:*. . * :***. *.***:******* :*****: :: *** :*** *::*:* * ******:.*:*:*** ***::*:.:* ** ********* ::*.*** *::*:**:*:::::.:***.*********:.**: * *********:********:: ***** .:* * *******:**:*********:* *:**:**: :**:*.: **:***:****::**. : *::.*** * * : : . * :*. :: . : : .: .* . **:* . *: : : : . :: :: : * ::* :* . . : . :: . **** : * .*::*::* . *.: ..* :*: :.: * :: :*.: : ::.. :: . * ::* * :: ::::*::: :*****: :. *: * . .. * * . : : . *: . * . * : *:* .. ****:*** .:*::*:.:. : *:*** : : .*. :* : ** *. *: :**:::**: **:: * *** .* *.*:* ***: * : :: .: : . . . .:*: ..*. . * : *. * : ", "identical_positions": 306, "similar_positions": 277, "identity": "28.57%" }, { "cls_id": "homologset.agr.RGD:1308598", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P21913-1", "uniprot_id": "SDHB_RAT", "id": "P21913-1", "name": "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial", "aln": "-----------------------------------------------------------------------------------------------------------------------------MAAVVGVSLKRGFSATALGRVGLQFQACREAQTAAA---------------------AAPRIKTFAIYRWDPDKAGDKPRMQTYKVDLNKCGPMVLDALIKIKNEIDSTLTFRRSCREGICGSCAMNINGGNTLACTRRIDTDLGKVSKIYPLPHMYVIKDLVPDLSNFYAQYKSIEPYLKKKDES--QEGKQQYLQSIEDREKLDGLYECILCACCSTSCPSYWWNGDKYLGPAVLMQAYRWMIDSRDEFTEERLAKLQDPFSLYRCHTIMNCTQTCPKGLNPGKAIAEIKKMMATYKEKRALA-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQA3-1", "uniprot_id": "SDHB_MOUSE", "id": "Q9CQA3-1", "name": "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial", "aln": "-----------------------------------------------------------------------------------------------------------------------------MAATVGVSLKRGFPAAVLGRVGLQFQACRGAQTAAA---------------------AAPRIKKFAIYRWDPDKTGDKPRMQTYEVDLNKCGPMVLDALIKIKNEVDSTLTFRRSCREGICGSCAMNINGGNTLACTRRIDTDLSKVSKIYPLPHMYVIKDLVPDLSNFYAQYKSIEPYLKKKDES--QEGKQQYLQSIEDREKLDGLYECILCACCSTSCPSYWWNGDKYLGPAVLMQAYRWMIDSRDDFTEERLAKLQDPFSVYRCHTIMNCTQTCPKGLNPGKAIAEIKKMMATYKEKRALA-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P21912-1", "uniprot_id": "SDHB_HUMAN", "id": "P21912-1", "name": "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial", "aln": "-----------------------------------------------------------------------------------------------------------------------------MAAVVALSLRRRLPATTLG--GACLQASRGAQTAAA---------------------TAPRIKKFAIYRWDPDKAGDKPHMQTYEVDLNKCGPMVLDALIKIKNEVDSTLTFRRSCREGICGSCAMNINGGNTLACTRRIDTNLNKVSKIYPLPHMYVIKDLVPDLSNFYAQYKSIEPYLKKKDES--QEGKQQYLQSIEEREKLDGLYECILCACCSTSCPSYWWNGDKYLGPAVLMQAYRWMIDSRDDFTEERLAKLQDPFSLYRCHTIMNCTRTCPKGLNPGKAIAEIKKMMATYKEKKASV-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A5PL98-1", "uniprot_id": "SDHB_DANRE", "id": "A5PL98-1", "name": "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial", "aln": "------------------------------------------------------------------------------------------------------------------------------MAAVCFSLSRCCSAVHRP----AVTAVRFAQTAAAPA-------------------AQPRIKKFQIYRWDPDTVGDKPRMQTYEIDLNTCGPMVLDALIKIKNEMDSTLTFRRSCREGICGSCAMNINGGNTLACLNKIDTNTSKVTKIYPLPHMYVVKDLVPDMSNFYAQYKSIEPYLKKKDES--QQGKQQYLQSVEDRQKLDGLYECILCACCSTSCPSYWWNADKYLGPAVLMQAYRWMIDSRDDFTEDRLSKLQDPFSLYRCHTIMNCTRTCPKGLNPGKAIAEIKKMMVTYKQKDAVAA----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P21801-1", "uniprot_id": "SDHB_YEAST", "id": "P21801-1", "name": "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial", "aln": "------------------------------------------------------------------------------------------------------------------------------MLNVLLRRKAFCLVTKKG--------MATATTAAAT--------------------HTPRLKTFKVYRWNPDEPSAKPHLQSYQVDLNDCGPMVLDALLKIKDEQDSTLTFRRSCREGICGSCAMNIGGRNTLACICKIDQNESKQLKIYPLPHMFIVKDLVPDLTNFYQQYKSIQPYLQRSSFP--KDG-TEVLQSIEDRKKLDGLYECILCACCSTSCPSYWWNQEQYLGPAVLMQAYRWLIDSRDQATKTRKAMLNNSMSLYRCHTIMNCTRTCPKGLNPGLAIAEIKKSLAFA------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P21914-1", "uniprot_id": "SDHB_DROME", "id": "P21914-1", "name": "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial", "aln": "----------------------------------------------------------------------------------------------------------------------------MLATEARQILSRVGSLVARNQMRAISNGTAQLEQQAQPKE-----------------AQEPQIKKFEIYRWNPDNAGEKPYMQTYEVDLRECGPMVLDALIKIKNEMDPTLTFRRSCREGICGSCAMNIGGTNTLACISKIDINTSKSLKVYPLPHMYVVRDLVPDMNNFYEQYRNIQPWLQRKNEAGEKKGKAQYLQSVEDRSKLDGLYECILCACCSTSCPSYWWNAEKYLGPAVLMQAYRWIIDSRDENSAERLNKLKDPFSVYRCHTIMNCTRTCPKGLNPGRAIAEIKKLLSGLASKPAPKLETAALHK---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VWN3-1", "uniprot_id": "Q9VWN3_DROME", "id": "Q9VWN3-1", "name": "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial", "aln": "MNLLRRQPRLLNKRSTWLFRNYVLANRDVSEPVSRPAAPMSTLSIPGPALAAATPVSAVSLVPRCTHSSLQGGGQGAGGRGLRGSATGGSAAGGIATKRQYSGGAAPAGAAKPGGAAPAGAAKPGGAAPAGAAKPGGAAAAAAGSAKPGGASTGKPASGNAPATPPPPPPPPPAKSAPPVKAKKPRLKTFEIYRWKP---GDQPQTQTYEVDLEQCGAMVLDALIKIKNEMDPTLTFRRSCREGICGSCAMNINGTNTLACVSSIDQNESKCCRIYPLPHLYVVRDLVPDMSQFYDQYRSIQPWLQRKDLKR-EAGTAQYLQSVDDRLVLDGLYECILCACCQTSCPSYWWNSNKYLGPAVLMQAYRWVIDSRDEATEQRLDFLKDPWKLYRCHSIMNCTNTCPKHLNPARAIIQLKQLLVGLKKKGKPQLKTDALFAGKA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . *::*.* :***.* . :* *:*::**. **.******:***:* *.********************.* ***** ** : .* ::*****:::::*****:.:** **:.*:*:*::.. : * : ***:::* *************.********* ::*************:*****: : * *::. .:****:*****.**** ***. ** ::*: : ", "identical_positions": 137, "similar_positions": 61, "identity": "31.07%" }, { "cls_id": "homologset.agr.RGD:1308599", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q505F5-1", "uniprot_id": "LRC47_MOUSE", "id": "Q505F5-1", "name": "Leucine-rich repeat-containing protein 47", "aln": "--------------------MAAAAMAVSEAWPELELAERERRRELLLTGPGLEERVKAAGGRLPPRLFTLPLLHYLEVSGCGSLRAPGPGLAQGLPQLHSLVLRRNALGPGLSPELGPLPALRVLDLSGNALETLPPGEGLGPAEPPGLPQLQSLNLSGNRLRELPADLARCAPRLQSLNLTGNRLDAFPPELFRPGALPLLSELAAADNCLRELSPDIAHLASLKTLDLSNNQLTEIPAELADCPKLKEINFRGNRLRDKRLEKMVGGCQTKSILEYLRAGGRGG-RSKGRQEASEKED-RKKRRERKQHRESGEGEE-EVADSARLMLKVLHVSENPTPLTVRVSPEVKDVRPYIVGAIVRGMDLQPGNALRRFLNSQTKLHDDLCEKRTAATIATHDLQAVRGPLLYAARPPEDLKIVPLGRKEAKAKELVRQLQLEAEEQRKQKKRQSVSGLHRYLHLLDGKENYPCLVDAEGDVISFPPITNSEKTKIKKTTCNLFLEVTSATSLQLCKDIMDSLILRMAELSKSTSENKEEDMLSGTEADAGCG-LSDPNLTLSSGKDGQCPLVVEQVRVVDLEGSLKVVYPSKTDLITLPPHVTVVR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1LT49-1", "uniprot_id": "F1LT49_RAT", "id": "F1LT49-1", "name": "Leucine-rich repeat-containing protein 47", "aln": "IIISGTRRKGAALRKRRTVGVMAAAMAVSEAWPELELAERERRRELLLTGPGLEERVKAAGGRLPPRLFTLPLLHYLEVSGCGSLRAPGPGLAQGLPQLHSLVLRRNALGPGLSPELGPLPALRVLDLSGNALETLPPGEGLGPAEPPGLPQLQSLNLSGNRLRELPADLARCAPRLQSLNLTGNCLDSFPAELFRPGALPLLSELAAADNCLRELSPDIAHLASLKTLDLSNNQLTEIPAELADCPKLKEINFRGNRLRDKRLEKMVGGCQTKSILEYLRAGGRGG-RSKGRQEGSEKED-RKKKRDRKQRRESGEGEE-EVADSARLMLKVLHVSENPTPLTVRVSPEVRDVRPYIVGAVVRGMDLQPGNALRRFLNSQTKLHDDLCEKRTAATIATHDLQAVRGPLLYAARPPEDLKIVPLGRKEAKAKELVRQLQLEAEEQRKQKKRQSVSGLHRYLHLLDGKENYPCLVDAEGDVISFPPITNSEKTKIKRTTCSVFLEVTSATSLQLCKDIMDSLVLKMAELNKSTSENKEEDMLSGTETDASHG-LSDPNLNPRAGKDGQCPLVVEQVRVVDLEGSLKVVYPSKADLVTLPPYVTVVR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N1G4-1", "uniprot_id": "LRC47_HUMAN", "id": "Q8N1G4-1", "name": "Leucine-rich repeat-containing protein 47", "aln": "----------------------MAAAAVSESWPELELAERERRRELLLTGPGLEERVRAAGGQLPPRLFTLPLLHYLEVSGCGSLRAPGPGLAQGLPQLHSLVLRRNALGPGLSPELGPLPALRVLDLSGNALEALPPGQGLGPAEPPGLPQLQSLNLSGNRLRELPADLARCAPRLQSLNLTGNCLDSFPAELFRPGALPLLSELAAADNCLRELSPDIAHLASLKTLDLSNNQLSEIPAELADCPKLKEINFRGNKLRDKRLEKMVSGCQTRSILEYLRVGGRGGGKGKGRAEGSEKEESRRKRRERKQRREGGDGEEQDVGDAGRLLLRVLHVSENPVPLTVRVSPEVRDVRPYIVGAVVRGMDLQPGNALKRFLTSQTKLHEDLCEKRTAATLATHELRAVKGPLLYCARPPQDLKIVPLGRKEAKAKELVRQLQLEAEEQRKQKKRQSVSGLHRYLHLLDGNENYPCLVDADGDVISFPPITNSEKTKVKKTTSDLFLEVTSATSLQICKDVMDALILKMAEMKKYTLENKEEGSLSDTEADAVSGQLPDPTTNPSAGKDGPSLLVVEQVRVVDLEGSLKVVYPSKADLATAPPHVTVVR", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** ****:**************************:****:***********************************************************************:****:********************************************* **:**.********************************************:********************:**********.****:*******.***** :.*** *.****: *:*:*:***:**.*:*** :*.*:.**:*:********.**********:*********:************:***.******:**********:***:*:**:*****.****:*************************************************:*********:****************:*:**..:***********:***:**:*:*:***:.* * *****. **.**:** * *.**. . :**** . **********************:** * **:*****", "identical_positions": 499, "similar_positions": 64, "identity": "82.48%" }, { "cls_id": "homologset.agr.RGD:1308600", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5FVL3-1", "uniprot_id": "DIK1B_RAT", "id": "Q5FVL3-1", "name": "Divergent protein kinase domain 1B", "aln": "MRRLRRLVHLVLLCPFSKGLQGRLPGLRVKYVLLVWLGIFVGSWMVYVHYSSYSELCRGHVCQVVICDQYQKGIISGSVCQDLCELQKVEWRTCLSSAPGQQVYSGLWQDKEVTIKCGIEEALNSKAWPDAVPRRELVLFDKPTRGTSIKEFREMTLSFLKANLGDLPSLPALVDQILLMADFNKDSRVSLAEAKSVWALLQRNEFLLLLSLQEKEHASRLLGYCGDLYLTESIPHGSWHGAVLLPALRPLLPSVLHRALQQWFGPAWPWRAKIAIGLLEFVEELFHGSYGTFYMCETTLANVGYTATYDFKMADLQQVAPEATVRRFLQGRHCEQSSDCIYGRDCRAPCDKLMRQCKGDLIQPNLAKVCELLRDYLLPGAPADLYEELGKQLRTCTTLSGLASQVEAHHSLVLSHLKTLLWREISNTNYS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99ML4-1", "uniprot_id": "DIK1B_MOUSE", "id": "Q99ML4-1", "name": "Divergent protein kinase domain 1B", "aln": "MRRLRRLVHLVLLCPFSKGLQGRLPGLRVKYVLLVWLGIFVGSWMVYVHYSSYSELCRGHVCQVVICDQYRKGIISGSVCQDLCELQKVEWRTCLSSAPGQQVYSGLWQDKEVTIKCGIEEALNSKAWPDAAPRRELVLFDKPTRGTSIKEFREMTLSFLKANLGDLPSLPALVDQILLMADFNKDSRVSLAEAKSVWALLQRNEFLLLLSLQEKEHASRLLGYCGDLYLTEGIPHGSWHGAVLLPALRPLLPSVLHRALQQWFGPAWPWRAKIAIGLLEFVEELFHGSYGTFYMCETTLANVGYTATYDFKMADLQQVAPEATVRRFLQGRHCEQSSDCIYGRDCRAPCDRLMRQCKGDLIQPNLAKVCELLRDYLLPGAPAGLYEELGKQLRTCTTLSGLASQIEAHHSLVLSHLKTLLWREISNTNYS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5VUD6-1", "uniprot_id": "DIK1B_HUMAN", "id": "Q5VUD6-1", "name": "Divergent protein kinase domain 1B", "aln": "MRRLRRLAHLVLFCPFSKRLQGRLPGLRVRCIFLAWLGVFAGSWLVYVHYSSYSERCRGHVCQVVICDQYRKGIISGSVCQDLCELHMVEWRTCLSVAPGQQVYSGLWRDKDVTIKCGIEETLDSKARSDAAPRRELVLFDKPTRGTSIKEFREMTLSFLKANLGDLPSLPALVGQVLLMADFNKDNRVSLAEAKSVWALLQRNEFLLLLSLQEKEHASRLLGYCGDLYLTEGVPHGAWHAAALPPLLRPLLPPALQGALQQWLGPAWPWRAKIAIGLLEFVEELFHGSYGTFYMCETTLANVGYTATYDFKMADLQQVAPEATVRRFLQGRRCEHSTDCTYGRDCRAPCDRLMRQCKGDLIQPNLAKVCALLRGYLLPGAPADLREELGTQLRTCTTLSGLASQVEAHHSLVLSHLKTLLWKKISNTKYS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*******.****:***** **********: ::*.***:*.***:********** **************:***************: ******** ***********:**:*********:*:*** .**.******************************************.*:*********.*********************************************.:***:**.*.* * ******..*: *****:********************************************************************:**:*:** **********:****************** ***.********.* ****.**************:****************::****:**", "identical_positions": 379, "similar_positions": 40, "identity": "87.94%" }, { "cls_id": "homologset.agr.RGD:1308601", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q96B23-1", "uniprot_id": "ARK2N_HUMAN", "id": "Q96B23-1", "name": "Protein ARK2N", "aln": "-------MKMEEAVGKVEELIESEAPPKASEQETAKEEDGSVELESQVQKDGVADSTVISSMPCLLMELRRDSSESQLASTESDKPTTGRVYESDS-SNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVEGDPSGVSGATVGRKSRRSRSESETS--TMAAKKNRQSSDKQNGRVAKVKGHRSQKHKERIRLLRQKREAAARKKYNLLQDSSTSDSDLTCDSSTSSSDDDEEVSGSSKTITAEIPDGPPVVAHYDMSDTNSDPEVVNVDNLLAAAVVQEHSNSVGGQDTGATWRTSGLLEELNAEAGHLDPGFLASDKTSAGNAPLNEEINIASSDSEVEIVGVQEHARCVHPRGGVIQSVSSWKHGSGTQYVSTRQTQSWTAVTPQQTWASPAEVVDLTLDEDSRRKYLL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6GF24-1", "uniprot_id": "A0A8I6GF24_RAT", "id": "A0A8I6GF24-1", "name": "", "aln": "-------MKMEEAVGKVEELTESAAPPKASEQETVKEEDGSVELESQVPKDGGAGSTVLSSMPCLLMELRRDSSESQLASTESDKPTTGRVYESDS-SNHCMLSPSSSGHLADSDTLSSVEENEPSQAETTVEGDTSGVPGATVGRKSRRSRSESETS--TMAAKKNRQSSDKQNGRVTKVKGHRSQKHKERIRLLRQKREAAARKKYSLLQDSSTSDSDLTCDSSTSSSDDEEEVSGSSKTITAEIPDGPPVVAHYDMSDTSSDPEVINVDNLLAAAVVQEHSNSVGGQDTGATWRTSELL-----EAGHLDPGFLASDKTSVGSAPLNEEINIASSDSEVEIVGVQEHARCAHPRGGVIQSVSSWKHGSGTQYVGSRPTQSWTAVTPQQTWASPAEVVDLTLDEDGRRKYLL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BH50-1", "uniprot_id": "ARK2N_MOUSE", "id": "Q8BH50-1", "name": "Protein ARK2N", "aln": "-------MKMEEAVGKVEELIESAAPPKASEQETAKEEDGSVELESQVQKDGVADSTVLSSMPCLLMELRRDSSESQLASTESDKPTTGRVYESDS-SNHCMLSPSSSGHLADSDTLSSVEENEPSQAETTVEGDTSGVSGATVGRKSRRSRSESETS--TMAAKKNRQSSDKQNGRVTKVKGHRSQKHKERIRLLRQKREAAARKKYNLLQDSSTSDSDLTCDSSTSSSDDDDEVSGSSKTITAEIP-GRGCFLN--------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M2B7W2-1", "uniprot_id": "A0A8M2B7W2_DANRE", "id": "A0A8M2B7W2-1", "name": "", "aln": "MTDAQKANELPECPSEGGATAEEQDMPLRQETTPTSSPAGEDPISSQSPDKQAPG---LLSMPCLLKELHRDSAPGQPQETAPPPSSTQSGPQEDSDSSVCLRSPSSSGHLGDSDTLSSAEEVAAP--------------TQTAGRKSRRSHSESDTSTVAMAAKKNRCQEKQVNGRVR-VRGPRSQRQKQRMRQLRQKREAAARRKPDVLQDSSTSDSDITAHSSSSSP-LTASSDNEGETINSHAPAGHRRADTSGASARGRGQLDLGVASGSLGGVLEEALTRFAAMQR------------------------------------QTEERFRVWMDRLTRLHSDDDLSSSENPEG--RSQVSSFLPSSESQ---ETLAAYQMARLNAMTVPPPPQTAGLNGNAEPPEPNV-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: *. .: *. * .* .... *. :.** .. .. : ****** **:***: .* .* . .:* :.** *. *: ********.*******.** .. *.*******:***:** :******* ...: **** *:* ***::*:*:* **********:* .:**********:*..**:**. . ....:**.:. * * ", "identical_positions": 104, "similar_positions": 64, "identity": "25.12%" }, { "cls_id": "homologset.agr.RGD:1308602", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "F1M753-1", "uniprot_id": "F1M753_RAT", "id": "F1M753-1", "name": "Low-density lipoprotein receptor-related protein 11", "aln": "---------------------------------------------------------------------------------------MAARGG-PGPGSRHRALRGLLLLCLWLPGGRPGEP-AAPP---------SGVDRLLQDFRRQLQRARPREELEPELLGG--------------------PQEDCPGAGGTAVYRAVSDTIIRTQDSIAAGASFLRAPGTVRGWRQCVAACCSEPSCSVAVVQLPRGPSVPSPVPAPRCYLFNCTARGRSVCKFAPLRGYRTYT----LSRAGDAAGIS-----PGPGE----------DEPPVSRAGKDVVLRLPTDGVVLDGRESTDDHAIVLYEWTLQQG------DPSSVDMKVPQPGTLKLSHLKEG----AYVFQLT-VTDSVGQRSSDNVSVTVLPRLRSTGGCSSACSRYHFFCDNGCCIDIALACDGVRQCPDGSDEDFCQNLALDRK---------LVTHTVATS--------------------------AQPGATGLNE-----------------------GEG-DPWLEKSQKATTHNQPATVSHPEKRIQPTQKAPESQINPVQPDSNSSGKN--QEE-KYDLKSKSD------QARGEHPAPEAGAVLPLALGLAITALLLLMVTCRLRLVKQKLKKARPIT--SEESDYLINGMYL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CB67-1", "uniprot_id": "LRP11_MOUSE", "id": "Q8CB67-1", "name": "Low-density lipoprotein receptor-related protein 11", "aln": "---------------------------------------------------------------------------------------MATRGGGPGPGFRHRALRGLLLLCLWLPGSRPGEP-AAPS---------SGVDRLLQDFRRQLQRARPREELEPELLGG--------------------PREDCPGAGGTAVYRAVPDTIIRTQDSIAAGASFLRAPGSVRGWRQCVTACCSEPSCSVAVVQLPRGPSVPAPMPAPRCYLFNCTARGRSVCKFAPLRGYRTYT----LSRAEDAAGIP-----PRPDE----------DKPPVSKAGKDVVLHLPTDGVVLDGRESSDDHAIVLYEWTLQQG------DPSSVDMKVPQPGTLRLSRLKEG----AYIFQLT-VTDSVGQRSSDNVSVTVLPRPYSTGGCSSACSRYHFFCDSGCCIDIALACDGVRQCPDGSDEDFCQNLALDRK---------LVTHTVATS--------------------------AQPGAMGLNE-----------------------GEG-DPKLEKSQRATTHNQPATVSHPETRIHSTQKAPESQINPVQPDSNSSGKN--QEEGNYDLKSKSG------QAGGEHPAPEAGAVLPLALGLAITVLLLLMVTCRLRLVKQKLKKARPIT--SEESDYLINGMYL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86VZ4-1", "uniprot_id": "LRP11_HUMAN", "id": "Q86VZ4-1", "name": "Low-density lipoprotein receptor-related protein 11", "aln": "----------------------------------------------------------------------------------MASVAQESAGSQRRLPPRHGALRGLLLLCLWLPSGRAALPPAAPLSELHA--QLSGVEQLLEEFRRQLQQERPQEELELELRAGGG------------------PQEDCPGPG-SGGYSAMPDAIIRTKDSLAAGASFLRAPAAVRGWRQCVAACCSEPRCSVAVVELPRRPAPPAAVLG--CYLFNCTARGRNVCKFALHSGYSSYS----LSRAPDGAALATARASPRQEK----------DAPPLSKAGQDVVLHLPTDGVVLDGRESTDDHAIVQYEWALLQG------DPS-VDMKVPQSGTLKLSHLQEG----TYTFQLT-VTDTAGQRSSDNVSVTVLRAAYSTGGCLHTCSRYHFFCDDGCCIDITLACDGVQQCPDGSDEDFCQNLGLDRK---------MVTHTAASP--------------------------ALPRTTGPSE-----------------------DAGGDSLVEKSQKATAPNKPPALSNTEKRNHSAFWGPESQIIPVMPDSSSSGKN--RKEESYIFESKGD------GGGGEHPAPETGAVLPLALGLAITALLLLMVACRLRLVKQKLKKARPIT--SEESDYLINGMYL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B7G6-1", "uniprot_id": "A0A8M2B7G6_DANRE", "id": "A0A8M2B7G6-1", "name": "Low-density lipoprotein receptor-related protein 11", "aln": "----------------------------------------------------------------------------------------------MFPRAHHVLLCAALLWVSSSAGARSSPTSELKSR-------ISGVEELLEEFRKQLQQDEPSS-----------------------------REQEGDGDRCVAGFRAAESRIIRASASIEQGAAFLSAPPRVFSWRDCARACCSLPHCTVAIIQEDLK----QPDDSLRCYLFNCTYRGKSVCSFSYQPGFSTYSRLNDSSGAPGTAATDRPAGRPAPALGEEEAMMQDLDEPPRSDAGQDLVVQLPTDWAVLDGRDSTDDHHITRYEWALVRG------DPS-VKMKVTHPGLLKLSGLREG----VYTFEIT-VIDTAGQKSSDNVSVSVLAPAPNAQVCTGHCSRYQFMCDDGCCIDIGYACDGKQHCPDRSDEDFCQNFDSGRKSSSSKHGADLQTEAAAQTPTEMQHTDISKPEAHQHYGFSNQDPCAAPPVVGPCKGVFPRWYYDSETGICQHFQYGGCKGNHNNFLQKSDCVNECIQKPTVAKHQTTATPLFS-FKSYTTPVASVHQEKRPNPLLDSQNSLAERKTQ------RLLEGHPPPESGAILPLAFGLLISALLLLMVGCRLFLVRRRLKKALPLT--TEESDYLINGMYL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9Y110-1", "uniprot_id": "Q9Y110_DROME", "id": "Q9Y110-1", "name": "MANSC domain-containing protein", "aln": "MIANLALPFLLMIAEAAATAEQVKYLEYLQSSPAEHRLSKRMDLEVCIGHFDVHKNTIIRTGESQAIGGKYLQGIELDTIEECERLCCETDACDVYIFERKAGGYCYLFECGPPEDFRCKFTRHANYTSAVLNPQPKPVGELVTTPRPQLPHIPSNNVSQQEWELSNLKLKPEARDKPTVSTAAVVAPTSGTGTGTGVGLGVGQSPVYQSQSVPAAHCGRFQFTCHSGECIAVYNACDGIPQCEDGSDEGPECNIVLSTATKPATTSSNLEPVKPMVSQYVPVQNVQQTQQVVAQQMQQQQPQQQQQQPQQQPQHVIVLGPPPPPPPPPPMVNNREDAAAWANRKMIAEGQQQLPQQQLQQQQQQQSSQPKTEIINTDAQSHIFSHKGGLQLQQPANGQGPPPSPLQVPGQMAGAGQVQVQGQSPTLQLPGYEANQAVYGMSRTGIYMPQQPAQLQAPAGQQQQQVQASVVWPQQAPLIPQQQSPVQQSQSLMPQQSGHVY------------------------AAAAPAIQSPPAAQQAMLPVLNAAPVAGKNQGPAADGDYDDYDEETYTEAPKKKQHKHKKVKTKTAKDPIELALEQNKLQPEGSLPALPVPASPVHEQYKMIHDNLAMEFRDHDGHSERPGGAVLSLTLGLLVTAALAILIGCRMRTVTRRARRLGGKTPYSQEADFLVNGMYL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: *: . * . . * .*: * ** : . . . * . . : ::. .. : . ** . * * . : . * *..: . . . ** .:: . .. : :*::. :: : : :.. . ..: * *:*. :* :::. .** . :. * :: .: . ** : . . * : :: : :: : .: * * . . : ::: : : :. : . . . : *. **:*.*::** ::. * ::: **: * :: :: * ::*:*:*:*****", "identical_positions": 49, "similar_positions": 118, "identity": "7.01%" }, { "cls_id": "homologset.agr.RGD:1308605", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JLJ4-1", "uniprot_id": "ELOV2_MOUSE", "id": "Q9JLJ4-1", "name": "Very long chain fatty acid elongase 2", "aln": "----------------------------------------MEQLKAFDNEVNAFLDNMFGPRDSR-VRGWFLLDSYLPTFILTITYLLSIWLGNKYMKNR--PALSLRGILTLYNLAITLLSAYMLVELILSSWEGGYN-LQCQNLDSAGEGDVRVAKVLWWYYFSKLVEFLDTIFFVLRKKTNQITFLHVYHHASMFNIWWCVLNWIPCGQSFFGPTLNSFIHILMYSYYGLSVFPSMHKYLWWKKYLTQAQLVQFVLTITHTLSAVVKP----------------CGFPFGCLIFQSSYMMTLVILFLNFYIQTYRKKPVKKELQE----KEVKNGFPKAHLIVANGMTDKKAQ---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A612-1", "uniprot_id": "ELOV2_RAT", "id": "D4A612-1", "name": "Very long chain fatty acid elongase 2", "aln": "---------------------------------------------------------MFGPRDSR-VRGWFLLDSYLPTFTLTIVYLLSIWLGNKYMKNR--PALSLRGILTLYNLGITLLSAYMLVELVLSSWEGGYN-LQCQNLDSAGEGDIRVAKVLWWYYFSKLVEFLDTIFFVLRKKTSQITFLHVYHHASMFNIWWCVLNWIPCGQSFFGPTLNSFIHILMYSYYGLSVFPSMHRYLWWKKYLTQAQLVQFVLTITHTLSAVVKP----------------CGFPFGCLIFQSSYMMTLVILFLNFYIQTYRKKPMKKEMPEGAAGKEVKNGFPKAHSIAANGVTDKKVQ---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NXB9-1", "uniprot_id": "ELOV2_HUMAN", "id": "Q9NXB9-1", "name": "Very long chain fatty acid elongase 2", "aln": "----------------------------------------MEHLKAFDDEINAFLDNMFGPRDSR-VRGWFMLDSYLPTFFLTVMYLLSIWLGNKYMKNR--PALSLRGILTLYNLGITLLSAYMLAELILSTWEGGYN-LQCQDLTSAGEADIRVAKVLWWYYFSKSVEFLDTIFFVLRKKTSQITFLHVYHHASMFNIWWCVLNWIPCGQSFFGPTLNSFIHILMYSYYGLSVFPSMHKYLWWKKYLTQAQLVQFVLTITHTMSAVVKP----------------CGFPFGCLIFQSSYMLTLVILFLNFYVQTYRKKPMKKDMQEPPAGKEVKNGFSKAYFTAANGVMNKKAQ---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P25358-1", "uniprot_id": "ELO2_YEAST", "id": "P25358-1", "name": "Fatty acid elongase 2", "aln": "MNSLVTQYAAPLFERYPQLHD--------YLPTLERPFFNISLWEHFDDVVTRVTNGRFVPSEFQFIAGELPLSTLPPVLYAITAYYVIIFGGRFLLSKS--KPFKLNGLFQLHNLVLTSLSLTLLLLMVEQLVPIIVQHGLYFAICNIGAWTQPLVTLYYMNYIVKFIEFIDTFFLVLKHKK--LTFLHTYHHGATALLCYTQLMGTTS-ISWVPISLNLGVHVVMYWYY---FLAARGIRVWWKEWVTRFQIIQFVLDIGFIYFAVYQKAVHLYFP--ILPHCGDCVGSTTATFAGCAIISSYLVLFISFYINVYKRKGTKTSRVVKRAHGGVAAKVNEYVNVDLKNVPTPSPSPKPQHRRKR", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P39540-1", "uniprot_id": "ELO1_YEAST", "id": "P39540-1", "name": "Fatty acid elongase 1", "aln": "---MVSDWKNFCLEKASRFR-----------PTIDRPFFNIYLWDYFNRAVGWATAGRFQPKDFEFTVGKQPLSEPRPVLLFIAMYYVVIFGGRSLVKSC--KPLKLRFISQVHNLMLTSVSFLWLILMVEQMLPIVYRHGLYFAVCNVESWTQPMETLYYLNYMTKFVEFADTVLMVLKHRK--LTFLHTYHHGATALLCYNQLVGYTA-VTWVPVTLNLAVHVLMYWYY---FLSASGIRVWWKAWVTRLQIVQFMLDLIVVYYVLYQKIVAAYFKNACTPQCEDCLGSMTAIAAGAAILTSYLFLFISFYIEVYKRGSASGKKKINKNN---------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P40319-1", "uniprot_id": "ELO3_YEAST", "id": "P40319-1", "name": "Fatty acid elongase 3", "aln": "MNTTTSTVIAAVADQFQSLNSSSSCFLKVHVPSIENPFG-IELWPIFSKVFEYFSG--YPAEQFEFIHNKTFLANGYHAVSIIIVYYIIIFGGQAILRALNASPLKFKLLFEIHNLFLTSISLVLWLLMLEQLVPMVYHNGLFWSICSKEAFAPKLVTLYYLNYLTKFVELIDTVFLVLRRKK--LLFLHTYHHGATALLCYTQLIGRTS-VEWVVILLNLGVHVIMYWYY---FLSSCGIRVWWKQWVTRFQIIQFLIDLVFVYFATYTFYAHKYLDG-ILPNKGTCYGTQAAAAYGYLILTSYLLLFISFYIQSYKKGGKKTVKKESEVSGSVASGSSTGVKTSNTKVSSRKA----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : . . * .. * : *: *. : .:.:. : ::** :* :* :: . . : . : .: : *: * :*: **.::**:::. : ***.***.: : : * .. :. ** :*::** ** .:.: :*** ::*: *::**:: : . * . . : : :.**:.**:: *:: . ", "identical_positions": 42, "similar_positions": 81, "identity": "11.51%" }, { "cls_id": "homologset.agr.RGD:1308606", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VQ97-1", "uniprot_id": "Q9VQ97_DROME", "id": "Q9VQ97-1", "name": "trypsin", "aln": "--MLLHWLVLVASVTLISAGS-------SPERIVGGHPVLISEVPWQAALMYSE---KYICGAVIYSDKIIITAAHCVERPFDTLYSVRVG-SVWKNLGGQHARVAVIRKHEDYVSSTILFNDIAVIRLVDTLIFNAEVRPIQLADSAPAAGTEASVSGWGEIGIL-WLQPTSLLKTSVKILDPNVCKRSY-----QYITKTMICAAAL--LKDSCHGDSGGPLVSGGQLVGIVSYGIG-CANPFFPGVYANVAELKPWILNAIEQL----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VQ98-1", "uniprot_id": "Q9VQ98_DROME", "id": "Q9VQ98-1", "name": "trypsin", "aln": "--MFVQWIFLAFSVTVVSSNW-------IPERIVGGDLITILSVPWQASILRLG---RFHCGAAIYSEDIVITAAHCLTDRETEFLSVRVG-SSFTFFGGQVVRVSSVLLHEEYDQS--WSNDIAVMRLQSKLRLGSAVSVIPLADTPPASGSPATVSGWGAIGFK-KNYPMSILSASVDIVDQDQCRRSYG----RKITKDMICAAAP--GKDACSGDSGGPLVSGNKLVGIVSFGKE-CAHPEYPGVYANVAELKPWILGAIERITKSE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P52905-1", "uniprot_id": "TRYI_DROME", "id": "P52905-1", "name": "Trypsin iota", "aln": "--MAVYGIVATVLVLLLLGDASD---VEATGRIIGGSDQLIRNAPWQVSIQISA---RHECGGVIYSKEIIITAGHCLHERSVTLMKVRVG-AQNHNYGGTLVPVAAYKVHEQFDSR-FLHYDIAVLRLSTPLTFGLSTRAINLASTSPSGGTTVTVTGWGHTDNG-ALS-DSLQKAQLQIIDRGECASQKFGYGADFVGEETICAAST--DADACTGDSGGPLVASSQLVGIVSWGYR-CADDNYPGVYADVAILRPWIVKAANAI----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "C0HKA3-1", "uniprot_id": "TRYGT_DROME", "id": "C0HKA3-1", "name": "Trypsin gamma", "aln": "--MLKFVILLSAVACALGGTVPEGLLPQLDGRIVGGSATTISSFPWQISLQRSG---SHSCGGSIYSSNVIVTAAHCLQSVSASVLQIRAG-SSYWSSGGVTFSVSSFKNHEGYNAN-TMVNDIAIIKINGALTFSSTIKAIGLASSNPANGAAASVSGWGTLSYGSSSIPSQLQYVNVNIVSQSQCASSTYGYG-SQIRSTMICAAAS--GKDACQGDSGGPLVSGGVLVGVVSWGYG-CAYSNYPGVYADVAALRSWVISNA-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "C0HKA4-1", "uniprot_id": "Y0031_DROME", "id": "C0HKA4-1", "name": "Trypsin delta/gamma-like protein CG30031", "aln": "--MLKFVILLSAVACALGGTVPEGLLPQLDGRIVGGSATTISSFPWQISLQRSG---SHSCGGSIYSSNVIVTAAHCLQSVSASVLQIRAG-SSYWSSGGVTFSVSSFKNHEGYNAN-TMVNDIAIIKINGALTFSSTIKAIGLASSNPANGAAASVSGWGTLSYGSSSIPSQLQYVNVNIVSQSQCASSTYGYG-SQIRSTMICAAAS--GKDACQGDSGGPLVSGGVLVGVVSWGYG-CAYSNYPGVYADVAALRSWVISNA-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "C0HKA2-1", "uniprot_id": "TRYDT_DROME", "id": "C0HKA2-1", "name": "Trypsin delta", "aln": "--MLKFVILLSAVACALGGTVPEGLLPQLDGRIVGGSATTISSFPWQISLQRSG---SHSCGGSIYSSNVIVTAAHCLQSVSASVLQIRAG-SSYWSSGGVTFSVSSFKNHEGYNAN-TMVNDIAIIKINGALTFSSTIKAIGLASSNPANGAAASVSGWGTLSYGSSSIPSQLQYVNVNIVSQSQCASSTYGYG-SQIRSTMICAAAS--GKDACQGDSGGPLVSGGVLVGVVSWGYG-CAYSNYPGVYADVAALRSWVISNA-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1Z8J8-1", "uniprot_id": "A1Z8J8_DROME", "id": "A1Z8J8-1", "name": "trypsin", "aln": "--MLKFVILLSAVACALGGTVPEGLLPQLDGRIVGGSATTISSFPWQISLQRSG---SHSCGGSIYSSNVIVTAAHCLQSVSASVLQIRAG-SSYWSSGGVTFSVSSFKNHEGYNAN-TMVNDIAIIKINGALTFSSTIKAIGLASSNPANGAAASVSGWGTLSYGSSSIPSQLQYVNVNIVSQSQCASSTYGYG-SQIRSTMICAAAS--GKDACQGDSGGPLVSGGVLVGVVSWGYG-CAYSNYPGVYADVAALRSWVINNA-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P04814-1", "uniprot_id": "TRYA_DROME", "id": "P04814-1", "name": "Trypsin alpha", "aln": "--MLKIVILLSAVVCALGGTVPEGLLPQLDGRIVGGSATTISSFPWQISLQRSG---SHSCGGSIYSANIIVTAAHCLQSVSASVLQVRAG-STYWSSGGVVAKVSSFKNHEGYNAN-TMVNDIAVIRLSSSLSFSSSIKAISLATYNPANGASAAVSGWGTQSSGSSSIPSQLQYVNVNIVSQSQCASSTYGYG-SQIRNTMICAAAS--GKDACQGDSGGPLVSGGVLVGVVSWGYG-CAYSNYPGVYADVAVLRSWVVSTANSI----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P35004-1", "uniprot_id": "TRYB_DROME", "id": "P35004-1", "name": "Trypsin beta", "aln": "--MLKFLILLSAVACALGGTIPEGLLPQLDGRIVGGTATTISSFPWQISLQRSG---SHSCGGSIYSARVIVTAAHCLQSVSASSLQIRAG-SSYWSSGGVVAKVSSFKNHEGYNAN-TMVNDIAVLHLSSSLSFSSTIKAIGLASSNPANGAAASVSGWGTESSGSSSIPSQLRYVNVNIVSQSRCSSSSYGYG-NQIKSSMICAFAS--GKDSCQGDSGGPLVSGGVLVGVVSWGYG-CAAANYPGVYADVAALRSWVINNA-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P35005-1", "uniprot_id": "TRYE_DROME", "id": "P35005-1", "name": "Trypsin epsilon", "aln": "--MLKFAVLLSVLACALAGTIPDGLLPQLDGRIVGGYETSIDAHPYQVSLQRYG---SHFCGGSIYSHDIVITAAHCLQSIEAKDLKIRVG-STYWRSGGSVHSVRSFRNHEGYNSR-TMVNDIAIIRIESDLSFRSSIREIRIADSNPREGATAVVSGWGTTESGGSTIPDHLLAVDLEIIDVSRCRSDEFGYG-KKIKDTMLCAYAP--HKDACQGDSGGPLVSGDRLVGVVSWGYG-CGDVRYPGVYADVAHFHEWIERTAEEV----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1ZA64-1", "uniprot_id": "A1ZA64_DROME", "id": "A1ZA64-1", "name": "trypsin", "aln": "MSLRLGLFLLAALGVVILTDSAS-----ISTHIVGGDQADIADFPYQVSVRLETYMLLHICGGSIYAPRVVITAAHCIKGRYASYIRIVAGQNSIADLEEQGVKVSKLIPHAGYNKK-TYVNDIGLIITREPLEYSALVQPIAVALEAPPSGAQAVVSGWGKRAEDDEALPAMLRAVELQIIEKSTCGAQYLTKD-YTVTDEMLCAGYLEGGKDTCNGDSGGPLAVDGVLVGVVSWGVG-CGREGFPGVYTSVNSHIDWIEEQAEAYL---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A1R3UCJ8-1", "uniprot_id": "A0A1R3UCJ8_RAT", "id": "A0A1R3UCJ8-1", "name": "", "aln": "--MLLLLTILQALAVAIVQSQGD-------DKILGGYTCVQNSQPWQVALQAGPGR-RFLCGGVLLSDQWVITAAHCARPLLHVALGKHNL--RRWEATQQVLRVVRQVPHPQYRPQ-AHDNDLMLLKLQRKVRLGRAVRTIPVARSCASPGTPCRVSGWGTTASPIVRYPTALQCVNVNIMPEQVCHRAYPG----TITSGMVCAGVPEGGKDSCQGDSGGPLVCQGQLQGLVSWGMERCAMPGYPGVYTNLCNYHSWIQRTMQSN----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CGR5-1", "uniprot_id": "KLK14_MOUSE", "id": "Q8CGR5-1", "name": "Kallikrein-14", "aln": "--MFLLLIILQALAVAIAQSQGD-------HKIIGGYRCVRNSQPWQVALQAGPGH-RFLCGGVLLSDQWVITAAHCARPILHVALGKHNI--RRWEATQQVVRVARQVPHPQYQPQ-AHDNDLMLLKLQKKVRLGRAVKTISVASSCASPGTPCRVSGWGTIASPIARYPTALQCVNVNIMSEQACHRAYPG----IITSGMVCAGVPEGGKDSCQGDSGGPLVCGGQLQGLVSWGMERCAMPGYPGVYANLCNYHSWIQRTMQSN----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P0G3-1", "uniprot_id": "KLK14_HUMAN", "id": "Q9P0G3-1", "name": "Kallikrein-14", "aln": "--MFLLLTALQVLAIAMTQSQEDE------NKIIGGHTCTRSSQPWQAALLAGPRR-RFLCGGALLSGQWVITAAHCGRPILQVALGKHNL--RRWEATQQVLRVVRQVTHPNYNSR-THDNDLMLLQLQQPARIGRAVRPIEVTQACASPGTSCRVSGWGTISSPIARYPASLQCVNINISPDEVCQKAYPR----TITPGMVCAGVPQGGKDSCQGDSGGPLVCRGQLQGLVSWGMERCALPGYPGVYTNLCKYRSWIEETMRDK----", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :*:** *:* :: . **. : : ::**.** * * : *: :: * :: . *: *:*** : ..:.* * : :** *:* *******. . * *:**:* *. :****:.: *: ", "identical_positions": 44, "similar_positions": 41, "identity": "16.24%" }, { "cls_id": "homologset.agr.RGD:1308607", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZN56-1", "uniprot_id": "D3ZN56_RAT", "id": "D3ZN56-1", "name": "", "aln": "MADPKMASQLQEDVTCPICLEILQDPVTIDCGHNFCLKC-INQIGKTS----------------------------ENILCPLCKCS-------VSKNTFRPNKLLASLAEK-IQTMDPADIQQEKEEARCQKHKKKLYYFCEQDGALLCVVCRDSKDHKFHDVTLIDEAVQNYKVQIESQAQDLGRKDKEIIEEKKRGEGAIWTFRAQVELEKLKVIEEFKHLRQRLDEEESFLLSRMDWLEKQGAKQLGQYVTVTEKQLNSLRTLTKSLKIRLQSSSIELLKDIKDTLSRNKEFQFLSPIPVPVDLEKKRSEAKARLESVLKSLTEFKDNLKAKGKKDKSEFVSSLNKEERESWSLLQKNNSMSPTPVPMTLDKDSADPDLTISHDGKKVTLYYIAGKASNKQAKPRPFYPFHCVRGSPGLSSGRRVWEAEIWEPSGGACIIGVATELAQGSQSQNIRMQNCIWALRISPTG-CQPFTNCKTQEHLQVCLKKVGVYVNHDCGEVIFYDAITSKHIYTFQTS-FNGRVFPLFGLQVTCSHITLTP----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R0K2-1", "uniprot_id": "TRI31_MOUSE", "id": "Q8R0K2-1", "name": "E3 ubiquitin-protein ligase TRIM31", "aln": "MAGQPLACQLQEEVTCPICMEILQDPVTIDCGHNFCLQC-ISQVGKTS----------------------------EKIQCPLCKLS-------VNKNTFRPNKLLASLAEK-IQSMDPADIQAEKEDSRCQRHKEKLHYFCEQDGAFLCVVCRDSKDHKSHNVTLIDEAAQNYKVQIESQAQDLGQKDKKIIEEKKQGEGAIWAFRAQVDLEKLKIHEEFKLLRQRLDEEESFLLSRLDWLEQQGAKQLRQYVTVTEKQLNSLRKLTKSLKIRLQSSSMELLKDIKDALSRGKEFQFLNPNPVPEDLEKKCSEAKARHESIIKTLTELKDDMNAEGKRDKSAFMNSLNKEEKESWSLLQKNNSVLPTSVPVTLDKSSADPDLTFSQDLKKVTLYIVAGKASNRQAKPRPFYPFHCVRGSPGLSSGRQVWEAEIRGPSGGACIVGVVTELARGAQSQTVSAQSYIWALRISPSG-CQPFTNCKAQEYLQVCLKKVGVYVNHDCGEVVFYDAITSKHIYTFQTS-FDGKVFPLFGLQVACSHITLSP----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BZY9-1", "uniprot_id": "TRI31_HUMAN", "id": "Q9BZY9-1", "name": "E3 ubiquitin-protein ligase TRIM31", "aln": "MASGQFVNKLQEEVICPICLDILQKPVTIDCGHNFCLKC-ITQIGETSC---------------------------GFFKCPLCKTS-------VRKNAIRFNSLLRNLVEK-IQALQASEVQSKRKEATCPRHQEMFHYFCEDDGKFLCFVCRESKDHKSHNVSLIEEAAQNYQGQIQEQIQVLQQKEKETVQVKAQGVHRVDVFTDQVEHEKQRILTEFELLHQVLEEEKNFLLSRIYWLGHEGTEAGKHYVASTEPQLNDLKKLVDSLKTKQNMPPRQLLEDIKVVLCRSEEFQFLNPTPVPLELEKKLSEAKSRHDSITGSLKKFKDQLQADRKKDENRFFKSMNKNDMKSWGLLQKNN--------HKMNKTSE-----------------------------------------PGSSS------------AGGRTTSGPPNHHS-SAPSHS--------LFRASSAG-KVTFPVCLLASYDEISGQ------GASSQDTKTFDVALSEELHAALSE-WLTAIRAWF-CEVPSS----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NTY9-1", "uniprot_id": "A0A8M1NTY9_DANRE", "id": "A0A8M1NTY9-1", "name": "", "aln": "----MSSSGGPLSVELSVCLDVFTDPVSTPCGHNLSKNSQICQYTKETLNQRPDLKINTTLREISDHYKLKSPDEGAVVVCDLCEDRTAVKSCLVCQSSYCETHLQPHLKVTGLKKHKLMHPVSNLEDYICQTHQRPLELFCRDDHMSVCLHCAVT-DHKTHNTVLLEDENQKMKAQLMETQRDLQKRIQDRFKEIQDIEQSAEARR-RVYTDLLKLMEDQQRAAEEQDSER-MSALEQEISELESRNTELEQLSHTEDHLHLIQIHSSLSSFRNTRSRSEISRKTRETLKR-------ALIKLKESIDEKLEQTVS---ADLKWMQQYAVDVTLDPHTAHPELILSDDGKQVSCGDIWQKLP--------NKLERFNR----------------------------------YLSVLGREGFSSGRFYFEVLVKG--KTDWTLGVARESVDRKGDIRVSPETGSWTVALINGNELSARADPPVLLSLRVSPQRVGVFVDYEEGLVCFYDVESSSHIYSYTDQCFSEKLHPCFSPGFNFEGKNSTPLIITHLSYNH", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* .:*:::: .**: ****:. :. * * : : . * **: * :.: . * * . :: . . : :: * *:. : **.:* :*. * : *** *:. *::: *: : *: . : * :: :. .: . :* : :: : : : :.*. : . :. : . :: ** :*: :: . . : . :: .. : .* * : .:::* .:: : : : : :: . : . :. * : :: .. .: ** .::: . * ** * . . . . . . .:. : . . . :*. *..::: . : : . * . . ", "identical_positions": 49, "similar_positions": 143, "identity": "8.81%" }, { "cls_id": "homologset.agr.RGD:1308609", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4AE75-1", "uniprot_id": "D4AE75_RAT", "id": "D4AE75-1", "name": "", "aln": "MSNAKERKHAKKMRSQPSNVTLSSGFVTERDGKRHFGG-KPSQSQKQELHSGTSRQWQIKMSPHLLPESDANEQTSSKTMFKKKGGWKAGPEGTSQEIPKYITASTFAQARAAEISAMLKAVTQKS--SNSLVFQTLPRHMRRRAMSHNVKRLPRRLQEMAKKEAEKAAHQKKEHSKNKCHKARRCHINRTLEFNRRQQKNIWLETHIWHAKRFHMVKRWGYCLGERPTAKSHRACYRAMTDL-----CLLQDLSYYCCLELKGKEEEILKALSQMCSIDTGLTFAAVHCLSGKRQGSLMLYRANKYPRDMLGPVTFIWKSRETPGDASEE-RQLWIWLHPTLKLAVLEEIKTTCQCSEPVKPSVCVPAPLLTPAQEDIQAGLADDKIGKKRKRRDDGENARRAKKTIGDGTGDPCQPRSWLSPTTGIVVSDLTMEMNRFRLVGPLSHCILTSALRAAPVHRGEEDAEETPHGWWTDTCRSPHGLSLHQRQEAVFQLLGGISSPAEIPAGTILGLTVRDPRVNLPPQRCRALPDPERYHVSEFICEEGMCTSSWSCAHWKPLSDHTDDPDNEQVKQLLLEGVPVECAHSFIWNQDICQSVTENKIVDQDLNRMRS-ELLVPGSQLVLGARESKIPILLIQQPG-KVTGEDRLGWGSGWDILLPKGWGMAFWIPFIYRG-ARVGGLKEAAVHSQYKRSPNVPGDFPDCRAG-VLFAEDQAKDLLEKYQRRPPAKRPNYVKLGTLAPFCCP-WEQLTRDWESRIQTQEAAVIDSVPGAQETDPRRLGVPCV--PKETCQLSNEASIAENQPRKPEVT---GCQAQAGTEVALEQNASEDHAAATGSQLCVVRSRKLLKQLSSWCGPSSE----VRRAPCRGQQELTRKACLSILADFPRALVWVSLSLLKKGSPEPHTMICVPSKEDLFQLSQDQCYHGPCESRHSDPFKSLILKEKEKKKKEKRQDGEQGASKGQAAGAPTAGQEARIQGLWSGPLP-----GLTSHCSRPLLGFVTHGDFSMAVGCGEALGFVSVTGLLEMLSSQSAAMRG------LVLLRPPTSLQYRFARVTIEV-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99575-1", "uniprot_id": "POP1_HUMAN", "id": "Q99575-1", "name": "Ribonucleases P/MRP protein subunit POP1", "aln": "MSNAKERKHAKKMRNQPTNVTLSSGFVADRGVKHHSGGEKPFQAQKQEPHPGTSRQRQTRVNPHSLPDPEVNEQSSSKGMFRKKGGWKAGPEGTSQEIPKYITASTFAQARAAEISAMLKAVTQKS--SNSLVFQTLPRHMRRRAMSHNVKRLPRRLQEIAQKEAEKAVHQKKEHSKNKCHKARRCHMNRTLEFNRRQKKNIWLETHIWHAKRFHMVKKWGYCLGERPTVKSHRACYRAMTNR-----CLLQDLSYYCCLELKGKEEEILKALSGMCNIDTGLTFAAVHCLSGKRQGSLVLYRVNKYPREMLGPVTFIWKSQRTPGDPSES-RQLWIWLHPTLKQDILEEIKAACQCVEPIKSAVCIADPLPTPSQEKSQTELPDEKIGKKRKRKDDGENAKPIKKIIGDGTRDPCLPYSWISPTTGIIISDLTMEMNRFRLIGPLSHSILTEAIKAASVHTVGEDTEETPHRWWIETCKKPDSVSLHCRQEAIFELLGGITSPAEIPAGTILGLTVGDPRINLPQKKSKALPNPEKCQD------------------------------NEKVRQLLLEGVPVECTHSFIWNQDICKSVTENKISDQDLNRMRS-ELLVPGSQLILGPHESKIPILLIQQPG-KVTGEDRLGWGSGWDVLLPKGWGMAFWIPFIYRG-VRVGGLKESAVHSQYKRSPNVPGDFPDCPAG-MLFAEEQAKNLLEKYKRRPPAKRPNYVKLGTLAPFCCP-WEQLTQDWESRVQAYEEPSVASSPNGKESDLRRSEVPCAPMPKKTHQPSDEVGTSIEHPREAEEVMDAGCQESAGPERITDQEASENHVAATGSHLCVLRSRKLLKQLSAWCGPSSEDSRGGRRAPGRGQQGLTREACLSILGHFPRALVWVSLSLLSKGSPEPHTMICVPAKEDFLQLHEDWHYCGPQESKHSDPFRSKILKQKEKKKREKRQKPGRASSDGPAGEEPVAGQEALTLGLWSGPLP-----RVTLHCSRTLLGFVTQGDFSMAVGCGEALGFVSLTGLLDMLSSQPAAQRG------LVLLRPPASLQYRFARIAIEV-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7KVW2-1", "uniprot_id": "Q7KVW2_DROME", "id": "Q7KVW2-1", "name": "", "aln": "-------------------------------------------------------------------------------MSTQKVEYDAALGGR-VTLPSHVTTYHYAAEALQEIRNLVADCQETTQRSSKLIFQTLPKHMRRRAMSHHPKRLPRKYRQAHKSQMGKSGNQP-VNGKRPSRKYRRRPKNLMREYVRRQRRHVWLETHIWHAKRFHMVDRWGHRLPYASCDKTYRACYRASAEH-----CLLQDISFYGCVELRGPLDMLREGFARLTSPQCGLGITARTFLSGRREGSVELFEDGRYPYGALQRASFMWRPRREEEDEKQTNHTLWLWLHPSGAQAVLNQLISVFQLKSTRQQKLPLNEAVTEEKMDVDKIEPVELSKETSPGKKNSKKKPEQRPLRFWTKTKAFDPQPSYFNSDGTLHLVLLQREFNRFRLTGPRAQKVLFASLR-------------------------PHREEELQDKANYCQAALQLSSPAELLSNLVMAHLVVDPRLQRPKKRTKAVGKMEQPPLS---------------------------------AGDLLMNQPKSLPESPLWSKKARERLAKGIMSAHKYDQLREQHAVVPGAPCAFEQQMQALPVILIQRPGSQDPRYKRLGYGCGWDVIAPAGYGMTLWLTLTMWG-ARPGGLRELDS---VAREAGAEIHLPDTLAG-VQRAAASADELRARYFRMPPNKRTNYRKLAVVSPFTAP-WRHLVRDWRASFSSASE---------------------------------------------------------------------------GSSFYVLRHRQQLEEIVESIRHRSP---LPQTLPDDAIIQIQLQLLSRGHVKDNALICLPTAADHKKRWRQLKHNDQAPVHVEPTQPDLNEQLRKELRQSHKLKLKRLRSRRVREKRRLQETATKRVHIRPANTAHLVRGQLQEMCRLWLPTDPAELRDSVRRQCSRQVFGYVSTAGFSFTEALVCAVGYVTPAGLQQLIEELPASKGNRKQPPLMCLVRDADSRDYRWASFQVNLNVASPTF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P41812-1", "uniprot_id": "POP1_YEAST", "id": "P41812-1", "name": "Ribonucleases P/MRP protein subunit POP1", "aln": "---------------------------------------------MSGSLSRGNGGKKVLNKNQLLKRNRIRNARSIRAEAVAASSTKTGTPSDLSESGSKLNVDQFISSRQFEVKQLQLAMHNSKAASSTRIFQALPRKLRRRTASHNVRRIPKRMRNRALREMRKSDQQDVLKGSSASSRKAHGLNAKQLYKARMSIKLLRLASKSTSMKLSMPPEVTSSNCHVRQKIKTLKRMIKESSTANPNIKLLNNRMGSYDCTGVN-ELAPIPKGRVKYTKRQKHFAWLPTHIWNAKRSHMMKRWG---YQMVWAPTQKCFKLTHRLGGDTCSSDGALCMDSSYIGTIIVKDKSNDSEGDFLKSIIGKLTAERANLRKYREGQVLFQGLIYSFNEENGEDSTKPLGPCDVFWVQKDTAIIR---LHPSIYTQVFNILLQHKEKLTVQDCRYSLASVTLKG---------------AKALESLASCLRSTEYSKSFEQFKMVSMITDHNALPQRCTFAFEAIDPRHLAAPKKLNDSQRKTVNSDD---------------------------------ILSLHENYPQDEINAVFNELCDPESRTQSYNNQNTLKEISARRYKLLTATPNSIN-KTTVPFKESDDPSIPLVIIRRLKT-RDWIVVLPWFWLLPLWHLLNRIPRMYHIGLRQFQQIQYENKQLYFPDDYPFTQLGYIENSFYKKEASKTKWDRKPMGKRINFEKIKDIHNTKLPAYSGEIGDFFSSDWRFLQILR------------------------------------------------------------------------NGIDYLQRNDKTLELMDSKKTGQFN----AQGVRDINCVNDVLEFCKDYEAKTKAMSLSIEENIPVALCKNRKCQFRTPDSISVNSSSFSLTFFPRCIIAVSCTLLERGHPKDNARIYQVPEKDLEHWLQLAKGVYRPNGRKDHDLKIPLPEVH-------------DLIGFITSGTYHLNCGNGMGIGFIDHHAAIRQPTR-------------YVLIRNVGTNTYRLGEWSKISV------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:. . . :.. : *: : :.. *.. :**:**:::***: **: :*:*:: :: : *: :* :.. . : : * . : : * :: * . . *: : : : * : :. * * :. : :. . : : . ..:*. : : * . : .:. * . * : : :: : . . :. :. : . : . : : : :. : ::: . : ::. : :. . *** . :: . * . * . .: : . : ::. : ..: . : : :*. : *. ** .* :: * : :.:* : **:: :. . * * : : . . :: * * ** *: *: : * : *: : .. : * : *: : : : . : : .* . . . . : . . : . *: : ::*::: . : : . .:*:: . *:* : ** . ", "identical_positions": 60, "similar_positions": 196, "identity": "5.53%" }, { "cls_id": "homologset.agr.RGD:1308611", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q499Q0-1", "uniprot_id": "Q499Q0_RAT", "id": "Q499Q0-1", "name": "Thiamine transporter 1", "aln": "MDVPARVSRRAAAAAARMLLRTARVPRECWFLPTALLCAYGFFANLRPSEPFLTPYLLGPDKNLTERQVFNEIYPVWTYSYLLLLFPVFLATDYLRYKPVILLQGLSLIVTWFMLLYAQGLLAVQFLEFFYGIATATEIAYYSYIYTVVDLGMYQKVTSYCRSATLVGFTVGSVLGQILVSVVGWSLFSLNVLSLTCVSVAFAVAWFLPMPQKSLFFHHIPSSCHGVNGLKVQNGGITTDTPASNHLPGWEDIESKIPLNLDEPPVEEPEEPKPDRLRVFKVLWNDFLMCYSSRPLLCWSVWWALSTCGYFQVVNYAQGLWEKVMPSQNAVIYNGGVEAVSTLLGASAVFAVGYIKLS--WSTWGEVTLFLCSLLIAAAVYIMDTVENIWVCYASYVVFRIIYMVLITIATFQIAANLSMERYALVFGVNTFIALALQTLLTLIVVDARG-LGLCIITQFLIYASYFAAISVVFLANGIVSIVKKCRKQEDPNSSPQATTS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EQN9-1", "uniprot_id": "S19A2_MOUSE", "id": "Q9EQN9-1", "name": "Thiamine transporter 1", "aln": "MDVPARVSRRAAAAAARMLLRTARVPRECWFLPTALLCAYGFFANLRPSEPFLTPYLLGPDKNLTERQVYNEIYPVWTYSYLLLLFPVFLATDYLRYKPVILLQGLSLIVTWFMLLYAQGLLAIQFLEFFYGIATATEIAYYSYIYTVVDLGMYQKVTSYCRSATLVGFTVGSVLGQILVSVVGWSLFSLNVISLTCVSVAFAVAWFLPMPQKSLFFHHIPSSCHGVNGLKVQNGGIVTDTPAANHLPGWEDIESKIPLNLDEPPVEEPEEPKPDRLRVFRVLWNDFLMCYSSRPLLCWSVWWALSTCGYFQVVNYAQGLWEKVMPSQNADIYNGGVEAVSTLLGASAVFAVGYIKLS--WSTWGEMTLFLCSLLIAAAVYVMDTVQSIWVCYASYVVFRIIYMVLITIATFQIAANLSMERYALVFGVNTFIALALQTLLTLIVVDARG-LGLCITTQFLIYASYFAAISVVFLANGIVSIIKKCRKQEDPSSSPQASTS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60779-1", "uniprot_id": "S19A2_HUMAN", "id": "O60779-1", "name": "Thiamine transporter 1", "aln": "MDVPGPVSRRAAAAAATVLLRTARVRRECWFLPTALLCAYGFFASLRPSEPFLTPYLLGPDKNLTEREVFNEIYPVWTYSYLVLLFPVFLATDYLRYKPVVLLQGLSLIVTWFMLLYAQGLLAIQFLEFFYGIATATEIAYYSYIYSVVDLGMYQKVTSYCRSATLVGFTVGSVLGQILVSVAGWSLFSLNVISLTCVSVAFAVAWFLPMPQKSLFFHHIPSTCQRVNGIKVQNGGIVTDTPASNHLPGWEDIESKIPLNMEEPPVEEPE-PKPDRLLVLKVLWNDFLMCYSSRPLLCWSVWWALSTCGYFQVVNYTQGLWEKVMPSRYAAIYNGGVEAVSTLLGAVAVFAVGYIKIS--WSTWGEMTLSLFSLLIAAAVYIMDTVGNIWVCYASYVVFRIIYMLLITIATFQIAANLSMERYALVFGVNTFIALALQTLLTLIVVDASG-LGLEITTQFLIYASYFALIAVVFLASGAVSVMKKCRKLEDPQSSSQVTTS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VGV6-1", "uniprot_id": "Q9VGV6_DROME", "id": "Q9VGV6-1", "name": "Thiamine transporter 1", "aln": "--------------------------MESWLKISCLLCIFGFLRELRPSEPYHAEILMGEWYHVTQDEVNRSVYPVGTYSYLALLIFVFLITDLLRYKPVIIANATTGICIWGTLIWTTTLSGLQAVEVFYGFYQAGEVAYYSYIYAKVDKQYYPRVTSHTRAAMFVGKLVAGILAQMVIGMRWMNYKQLFYITVTSQVAALLWAFFLPKVEKSLYFHNRS---EAIEGGTKSDGGNLEKGSEQ---------------------PSNEEASQEKKIPALQLLWSHFRSAYTNPLVIQWSLWYAISLAGFLQITTYMQVVWKSFENEP-TIAWNGAVDVALTLLSAVFALLAGYFHAGRLNTRSSLLSMALLSVLEGGCVLLSCWTDDIYLSYLGYVLYGGLFAFTITVASSELASSLEEDSFALVFGFNTFVGLLLQCILTFVVVSEKANLNLNVFQQFSVYAFYFIVIGIVYSIAVILQYIWSISKKPKAIQEAN----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VGV5-1", "uniprot_id": "Q9VGV5_DROME", "id": "Q9VGV5-1", "name": "Thiamine transporter 1", "aln": "--------------------------MKEWLKISCLLCVFGCIREIRPSEPYVTEYLLGPWRNITEQQLTHDVYPVGTYSYLVQLVFVFLITDFLRYKPLIITIGAAGVIIWSMLIWTTSLLSLQILEFFFGTYMAAEVAYYTYIYAKVDKKYYARVTSHTRAAMFAGKLVSGITSQLMLNLELMNYKELNYITLGTQIIAMLWAFGLPRVDRSLYFHREQ---LSITEPQTQLPG-VGNLAEM---------------------DQQQENTQ-KQPGALSLLWLHFRNAYTNPRVVQWSLWYAIGLAGYLQVTYYVQVLWKVIEPEP-VIAWNGAVDAVLTALAALSALAAGYLHTGRLRPRASLLILGILSAVEGGCVLICCWTQDIYWSYAGFVLFGALYGFTITVASAEVARNLEEESFGLVFGVNTFVALIFQSLLTIIFVTDTG-FELDPVGQYTAYAFYFIGVGVLYLISVLIEYLMCRNNDVEKLENSLD---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VK64-1", "uniprot_id": "Q9VK64_DROME", "id": "Q9VK64-1", "name": "Thiamine transporter 1", "aln": "--------------------------MKSWLKISLLLCTFGFFREFRPSEPYVTEYLASDYGNLTTDQIYQDVYPFGTYSVLAQLVIVFLITDLVRYKPVIVLSALAGITLFSMLIWTETVGMLQVAQVFFGTFTAAEVAYYTYMYAKVNKEQYQVVTGHTRAAILSGKFLGGLFAQILVSTDSMDYRQLHYLSLATQLISLAVSLFLPSVPRSLYFYAGS---EKIT---------IADGEET---------------------SPKFSFAN-----ACRLLWYHLVSSYSNPVVLQWSIWWALATCGQVQVISYIQFLWKEVAPNK-LSVYNGGVEAVATLLGAIGAILAGLLNSNKRRG-SYMMGISICAAALGALLIYAAKTQLIWVAYVNYVLFCTVFFFIITVAGAVVAENLVEDSFGLIFGINTLVGLILQTILTVAVVERVG-FALEPRDQYVVYGSYFVVLGGISIIGSICVKLFCRTNK-SSVENVVSLT-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *: : *** :* : .:*****: : * . ::* :: ..:**. *** * *. *** ** :****::: . : : : *::: : :* :.*:* * *:***:*:*: *: * **.: *:* : * :..: .*:::. . .* ::: :: : ** :**:*: : . : . .: . :** .: .*:. :: **:*:*:. .* .*: * * :*: . . :**.*:.. * *.* .: .* :: . : : : : .. : . *: .* .:*:: :: . **:* :* .* : :.*:**.**::.* :* :**. .* . : * *: *. ** :. : : : . .. ", "identical_positions": 95, "similar_positions": 146, "identity": "18.96%" }, { "cls_id": "homologset.agr.RGD:1308612", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "G3V751-1", "uniprot_id": "G3V751_RAT", "id": "G3V751-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------MGEAEVGGTGAPGDKGPGEAAPSPAEETVVWSPEVEVCLFHAMLGHKPVGVNRHFHMICIRDKFSQN----IGRQVPSKVIWDHLSTMYDMQALHESEILPFPNPERNFVLPDEIIQEVREGKVVIEEEMKEEMKEDVDPHSGADD---------------------------------------------VFSSSGSLGKALEKSSKDKEKN---SSDLGCKEGADKRKRSRVTD--------------KVLTANSNPSSPSAAKRRRT--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DAT2-1", "uniprot_id": "MRGBP_MOUSE", "id": "Q9DAT2-1", "name": "MRG/MORF4L-binding protein", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------MGEAEVGGTGAPGDKGPGEAAPSPAEETVVWSPEVEVCLFHAMLGHKPVGVNRHFHMICIRDKFSQN----IGRQVPSKVIWDHLSTMYDMQALHESEILPFPNPERNFVLPDEIIQEVREGKVVIEEEMKEEMKEDVDPHSGADD---------------------------------------------VFSSSGSLGKALEKSSKDKEKN---SSDLGCKEGADKRKRSRVTD--------------KVLTANSNPSSPSAAKRRRT--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NV56-1", "uniprot_id": "MRGBP_HUMAN", "id": "Q9NV56-1", "name": "MRG/MORF4L-binding protein", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------MGEAEVGGGGAAGDKGPGEAATSPAEETVVWSPEVEVCLFHAMLGHKPVGVNRHFHMICIRDKFSQN----IGRQVPSKVIWDHLSTMYDMQALHESEILPFPNPERNFVLPEEIIQEVREGKVMIEEEMKEEMKEDVDPHNGADD---------------------------------------------VFSSSGSLGKASEKSSKDKEKN---SSDLGCKEGADKRKRSRVTD--------------KVLTANSNPSSPSAAKRRRT--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7K003-1", "uniprot_id": "MRGBP_DROME", "id": "Q7K003-1", "name": "MRG/MORF4L-binding protein", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------MMAKDKGLAVAG-----TAAPLPAALDHEWSAEEELQLFHAMEGLRPVGINKHFYMSCIVQRLSKS----LNREMPSELIWRHLGTMYKLKELDDLESLPFPNEEREFSLPEQDYGTLQTKKTVEVHANEEAAEAQSAPPTAETN---------------------------------------------GKAPPATKTPVPTNSTKDGDKKPVAKPQEQLPKRPAKRTRGSMSN--------------ESISPSTTPPPVQSNKRRRI--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53911-1", "uniprot_id": "EAF7_YEAST", "id": "P53911-1", "name": "Chromatin modification-related protein EAF7", "aln": "MVVHWTIVDEIRLLRWASEFKPAGIHKHFHMFCIVERMNSPDKYPVTLLQKETMKLGKVFTAKDIWDKLSQSYNLEKIDEMENTYSLEATTESSRNGNGNGDDAEIHEETLLELNNRIRVRKQDFTLPWEEYGELILENARKSPNSNEEYPRVEDMNEKDSTIPKESPSTDLKNDNNKQEKNATIKVKELPEYHTEENDSPIDVQKEPIKEVQSDEKELQREHMSEEEQKMKSTNKTAAPVRKSQRLKRSKEVKFEDEEKEEIEEDNTKDEEQKEKKEEIQEPKITHNEEVDKEKNENEEGDDEREKSTSYENTNGSESEGVDEGVDEELGYESEREAEGKGKQIESEGGNLKKKTENKKGDDQQDDTKKDSKDKNEPLAKRTRHSSSTGNTSNETSPKRKRRKAGSRKNSPPATRVSSRLRNKK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . *: :*: . *:.:::. :. . . .: : ..: . : *. : : * : *:: :: : * . : : : . : : .. :.. * ::. . . : **.* : : : ...*.. .* * ", "identical_positions": 14, "similar_positions": 61, "identity": "3.29%" }, { "cls_id": "homologset.agr.RGD:1308613", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8C1R0-1", "uniprot_id": "TSSK5_MOUSE", "id": "Q8C1R0-1", "name": "Testis-specific serine/threonine-protein kinase 5", "aln": "MRSSSWRKSDQRVFIEQVRECMNNGYLLSSKKIGSGAFSKVYLAYATRERMKHNPRLSSDLRGKRHTMVAIKIVSMAEAPAEYSRKFLPREILSLNATYKHMNIVQLYETYQNSQRSYLVLELAARGDLLEHINAVSDLRCCPGLEEEEARRLFWQLVSAVAHCHNVGIVHRDLKCENILLDDQGFIKLTDFGFANWVGLKNSLLSTFCGSVAYTAPEILMSKKYNGEQADLWSLGIILHAMVSGKLPFKEHQPHRMLNLIRRGPIFRPGLSPECRDLIRGLLQLHPCERLDLQQVAAHCWMLPAEHMLSSALGAPREQDHSWSTVAPDNTEPDRDTRHARSKGSSSSSGRTSPRRPSLAQLCNTWKPAPEQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZJ84-1", "uniprot_id": "D3ZJ84_RAT", "id": "D3ZJ84-1", "name": "non-specific serine/threonine protein kinase", "aln": "MRSNSRRKEDQRVFIEQVRECMNNGYLLSSKKIGSGAFSKVYLAYATRERMKHNPRLSSDLRGKHHSMVAIKIVSMAEAPAEYSRKFLPREILSLNATYKHMNIVQLYETYQNSQRSYLVLELAARGDLLEYINAVSDLRCCPGLEEEEARRLFWQLVSAVAHCHSVGIVHRDLKCENILLDDQGFLKLTDFGFANWVGIKNSLLSTFCGSVAYTAPEILMSKKYNGEQADLWSLGIILHAMVSGKLPFKEHQPHRMLHLIRRGPIFRPRLSPECRDLIRGLLQLHPGDRLDLQQVAAHCWMLPAEHMLSSVLGATREQKHSWSAIGPDNAEPDRDTRYSRSKGSSPSSGRTSPRRASLAQLCSTWKPAPEE", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***.* **.*******************************************************:*:****************************************************************:*********************************.********************:************:**********************************************************:********** ***************** :**********************.***.***.****::.***:*******::******.*********.******.*******:", "identical_positions": 346, "similar_positions": 23, "identity": "93.01%" }, { "cls_id": "homologset.agr.RGD:1308614", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q64057-1", "uniprot_id": "AL7A1_RAT", "id": "Q64057-1", "name": "Alpha-aminoadipic semialdehyde dehydrogenase", "aln": "MLR-LARPLCVQTVKASKLSRLWSRPAALMSTLLIHHPQYAWLQDLGLREDNEGVFNGSWGGRGEVITTYCPANNEPIARVRQASMKDYEETIGKAKKAWNIWADIPAPKRGEIVRKIGDALREKIQLLGRLVSLEMGKILVEGIGEVQEYVDVCDYAAGLSRMIGGPTLPSERPGHALMEQWNPLGLVGIITAFNFPVAVFGWNNAIALITGNVCLWKGAPTTSLVSIAVTKIIAKVLEDNLLPGAICSLTCGGADMGTAMARDERVNLLSFTGSTQVGKQVALMVQERFGKSLLELGGNNAIIAFEDADLSLVLPSALFAAVGTAGQRCTTVRRLFLHESIHDEVVDRLKNAYSQIRVGNPWDPNILYGPLHTKQAVSMFVQAVEEAKKEGGTVVYGGKVMDHPGNYVEPTIVTGLVHDAPIVHKETFAPILYVFKFKNEEEVFEWNNEVKQGLSSSIFTKDLGRIFRWLGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQYMRRSTCTINYSTALPLAQGIKFQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DBF1-1", "uniprot_id": "AL7A1_MOUSE", "id": "Q9DBF1-1", "name": "Alpha-aminoadipic semialdehyde dehydrogenase", "aln": "MWR-VPRRLCVQSVKTSKLSGPWSRPAAHMSTLLIHHPQYAWLQDLGLREDNEGVYNGSWGGRGEVITTYCPANNEPIARVRQASLKDYEETIGKAKKAWNIWADIPAPKRGEIVRKIGDAFREKIQLLGRLVSLEMGKILVEGIGEVQEYVDVCDYAAGLSRMIGGPTLPSERPGHALIEMWNPLGLVGIITAFNFPVAVFGWNNAIALITGNVCLWKGAPTTSLVSVAVTKIIAQVLEDNLLPGAICSLVCGGADIGTTMARDERVNLLSFTGSTQVGKEVALMVQERFGKSLLELGGNNAIIAFEDADLSLVVPSVLFAAVGTAGQRCTTVRRLFLHESIHNEVVDRLRSAYSQIRVGNPWDPNILYGPLHTKQAVSMFVRAVEEAKKQGGTVVYGGKVMDHPGNYVEPTIVTGLAHDAPIVHQETFAPILYVFKFQDEEEVFEWNNEVKQGLSSSIFTKDLGRIFRWLGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQYMRRSTCTINYSTSLPLAQGIKFQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49419-1", "uniprot_id": "AL7A1_HUMAN", "id": "P49419-1", "name": "Alpha-aminoadipic semialdehyde dehydrogenase", "aln": "MWR-LPRALCVHAAKTSKLSGPWSRPAAFMSTLLINQPQYAWLKELGLREENEGVYNGSWGGRGEVITTYCPANNEPIARVRQASVADYEETVKKAREAWKIWADIPAPKRGEIVRQIGDALREKIQVLGSLVSLEMGKILVEGVGEVQEYVDICDYAVGLSRMIGGPILPSERSGHALIEQWNPVGLVGIITAFNFPVAVYGWNNAIAMICGNVCLWKGAPTTSLISVAVTKIIAKVLEDNKLPGAICSLTCGGADIGTAMAKDERVNLLSFTGSTQVGKQVGLMVQERFGRSLLELGGNNAIIAFEDADLSLVVPSALFAAVGTAGQRCTTARRLFIHESIHDEVVNRLKKAYAQIRVGNPWDPNVLYGPLHTKQAVSMFLGAVEEAKKEGGTVVYGGKVMDRPGNYVEPTIVTGLGHDASIAHTETFAPILYVFKFKNEEEVFAWNNEVKQGLSSSIFTKDLGRIFRWLGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQYMRRSTCTINYSKDLPLAQGIKFQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PLI9-1", "uniprot_id": "AL7A1_DANRE", "id": "A0A8M1PLI9-1", "name": "Alpha-aminoadipic semialdehyde dehydrogenase", "aln": "MQRVLTLRLARLFTQRHKLLPSVRTAAPNMSTLLINQPEYNWLKELGLKEDNDGVYNGSWGGQGEVVTSYCPANNEPIARVRQATIAEYEETIQKALDAWKVWADVPAPKRGEIVRQIGEALRRKIKALGSLVSLEMGKIYVEGVGEVQEYVDVCDYAVGLSRMIGGPILPSERPGHVLIEQWNPVGLVGIITAFNFPVAVYGWNNAIALICGNACLWKGAPTTPLTSVAVTKIVAEVLEQNHLPGAICSMTCGGADIGMAMAKDERVGLLSFTGSTHVGKQVAMMVQERFGRQLLELGGNNAIIVFEDADLSLVVPSAVFASVGTAGQRCTTTRRLMLHESIHDEVVERIAKAYKQIRIGDPWDPNTLYGPLHTKQAVQQYLAAIEQAKQQGGTLVCGGKIMDRPGNYVEPTIITGLPHNASIVHTETFVPILYVLKFKTEEEAFSWNNEVKQGLSSSIFTKDMGRVFRWLGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDSWKQYMRRSTCTINYSKDLPLAQGIKFE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * :. *. .: ** .*. ******::*:* **::***:*:*:**:******:***:*:***************:: :****: ** .**::***:**********:**:*:*.**: ** ********* ***:********:****.********* *****.**.*:* ***:***************:*******:* **.*********.* *:*****:*:***:* *******:.*****:* :**:****.********:***:*.:*******:.***********.*********:**.:**:**********.***::*****:***:*: .** ***:*:***** ***********. :: *:*:**::***:* ***:**:*********:*** *:*.*.* ***.*****:**: ***.* *****************:**:********************************************:***************. *********:", "identical_positions": 404, "similar_positions": 96, "identity": "74.81%" }, { "cls_id": "homologset.agr.RGD:1308615", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AXR5-1", "uniprot_id": "S35A3_RAT", "id": "Q6AXR5-1", "name": "UDP-N-acetylglucosamine transporter", "aln": "-MSANLKYLSLGILVFQTTSLVLTMRYSRTLKEEGPRYLSSTAVVVAEFLKIMACIFLVYKDSKCSVRTLNRVLHDEILNKPMETLKLAIPSGIYTLQNNLLYVALSNLDAATYQVTYQLKILTTALFSVSMLGKKLGMYQWLSLVILMAGVAFVQWPSDSQELNSKD-LSTGSQFVGLMAVLIACFSSGFAGVYFEKILKETKQSVWIRNIQLGFFGSIFGLMGVYVYDGELVSKNGFFQGYNQLTWIVVVLQALGGLVIAAVIKYADNILKGFATSLSIILSTIISYFWLQDFVPTSVFFLGAILVIAATFLYGYDPKPAGNPTKA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R1T4-1", "uniprot_id": "S35A3_MOUSE", "id": "Q8R1T4-1", "name": "UDP-N-acetylglucosamine transporter", "aln": "-MSANLKYLSLGILVFQTTSLVLTMRYSRTLKEEGPRYLSSTAVVVAEFLKIMACIFLVYKDSKCSVRALNRVLHDEILNKPMETLKLAIPSGIYTLQNNLLYVALSNLDAATYQVTYQLKILTTALFSVSMLGKKLGVYQWLSLVILMAGVAFVQWPSDSQELNSKD-LSTGSQFVGLMAVLTACFSSGFAGVYFEKILKETKQSVWIRNIQLGFFGSIFGLMGVYVYDGELVSKNGFFQGYNQLTWIVVALQALGGLVIAAVIKYADNILKGFATSLSIILSTIISYFWLQDFVPTSVFFLGAILVIAATFLYGYDPKPAGNPTKA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y2D2-1", "uniprot_id": "S35A3_HUMAN", "id": "Q9Y2D2-1", "name": "UDP-N-acetylglucosamine transporter", "aln": "-MFANLKYVSLGILVFQTTSLVLTMRYSRTLKEEGPRYLSSTAVVVAELLKIMACILLVYKDSKCSLRALNRVLHDEILNKPMETLKLAIPSGIYTLQNNLLYVALSNLDAATYQVTYQLKILTTALFSVSMLSKKLGVYQWLSLVILMTGVAFVQWPSDSQ-LDSKE-LSAGSQFVGLMAVLTACFSSGFAGVYFEKILKETKQSVWIRNIQLGFFGSIFGLMGVYIYDGELVSKNGFFQGYNRLTWIVVVLQALGGLVIAAVIKYADNILKGFATSLSIILSTLISYFWLQDFVPTSVFFLGAILVITATFLYGYDPKPAGNPTKA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0V2R5-1", "uniprot_id": "B0V2R5_DANRE", "id": "B0V2R5-1", "name": "", "aln": "MASAKLKYLSLGVLVFQTTSLVLTMRYSRTLQGDGPRYLASSAVVVAEFLKILTCVGLVFKENSYSGRALSSIMRQEIIHKPVETLKLAIPSGIYTLQNNLLYVALSNLDAATYQVTYQLKILTTALFSVSMLGRRLGVYQWLSLLILMAGVAFVQWPTDSPADPQKEHLTAGSQFVGLVAVLVACCSSGFAGVYFEKILKETKQSVWVRNIQLGLFGLVFGVFGMLAYDGDRVREHGMFQGYNTLTWIVVALQALGGLVIAAVIKYADNILKGFATSLSIILSTLISYFLLEDFEPTSVFFLGAILVIMATFLYGYENKPPSNPSRA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:***:***:******************: :*****:*:******:***::*: **:*:.. * *:*. ::::**::**:**************************************************.::**:******:***:********:** .*: *::*******:*** ** *********************:******:** :**::*: ***: * ::*:***** ******.*********************************:**** *:** ************* *******: **..**::*", "identical_positions": 249, "similar_positions": 54, "identity": "75.91%" }, { "cls_id": "homologset.agr.RGD:1308616", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZUQ8-1", "uniprot_id": "D3ZUQ8_RAT", "id": "D3ZUQ8-1", "name": "", "aln": "MASERPEPEVEEAGQVFLLMKKDYRISRNVRLAWFLNHLHQTVQAIPQESLLQSEQELEVLSVLPPGWQPDEPVVPRPFLLVPSTRVTFLAWQYRFVIELDLSPSTGIVDDSTGEILFDEVFHALSRCLGGLLRPFRVPGSCIDFQPEIYVTIQAYSSIIGLQSHQVLVQGCLLDPSRREAFLQQVYEQLCLFEEKVATMLQQQHEPQSQAEDQSPESGESLGRKVGVSMVTADLGLVSMIRQGILALQLLPSNSSAGIIVITDGVTSVPDVAVCETLLNQLRSGTVACSFVQVGGVYSYDCSFGHVPNVELMKFIAMATFGSYLSTCPEPEPGNLGLTVYHRAFLLYSFLRSGEALNPEYYCGSQHRLFNEHLVSASSNPALALRRKKHTEKEVPADLVSTVSVRLREGYSVREVTLAKAGSQLEVKLVLLWKHNMRIEYVAVAPWPLEPEGPRGTRVEVTMEGGYDILHDVSCALRQPIRSLYRTHVIRRFWNTLQSINQTDQMLAHLQAFSSVPEHFTLPDSTKSGVPLFYIPPGSGTPVLSLQHSGSDSSHAQFAAYWKPVLSMDANSWQRWLHMHRLVLILEHDTPLPKHLHTPGSNGRYSTIQCRISHSSLTSLLRDWSSFVLVEGYSYVKLLSSAPDQPPSSFYMVRIISKAPCMVLRLGFPIGTPAQARHKIVSGLQEEILRLRFPHRVQSKEPTPKVKRKGLGGVGG-SSPSKSPPTLGPQQALSDRPCLVVLHKPLDKLLIRYEKLPLDYRAPFLLTLEPPGPLPLVSGRSASSSLASLSRYLYHRRWLWSVPSGLAPTLPLSAIAQLLSVLTEVRLSEGFHFACSGEGIINMVLELPVQNDPLGQAAAEEKHTCVVQYILFPPHSTSTKDSFSTDDDNDVEVEALEGDSELNLVTEVWVEPQYGRVGPGPESWKHLQDLTYSEIPQALHPRDAACIGSLLTFEYLIQLCQSKEWGPLPPEPQVSDGLDQRGDTCVHEIPFRFDLLGLLPQCQQLQMFFLLLSREPEGVPLTEGPCPTNDMVLCLLHSCLGQELSDREIPLTTADQTAFLNEVLRRSSLDPGPEGALVGGHAIPKDQAGNRTQATGDSTLPTQSVGIPGIPRSSISAQPPQWHCYARLLSPQHVFLTFLPATFSDVQHLTAYGLVGSSQEETKPKLGDWSGAPSLKDLGAAGTRAPKSQVPILSVTLASDSTQNPGEPSPPSCRDFPANSGRQAPQTEGADGPRTRCPVYIYSCSLEALREQMVGLQPPQAPRDLIFRTQDLDHPSSSSAWMEPRYKEAATHCALLQEHAQRCFVRGLFRSLQQAQSVTCQDLLTAVDACEELLQEVDITSFLLALCGHTWGLPHAPPSPGPLSPGPFSSSIEEGPEPRERAILVSESSIETEDLSEPEFQSTRVPGNSDPGPEISLTDVCQLRGEAHDALHSLIQEKFLEISRLHFRTVPSNPHYFFYCPPSSRREDEGPRDTVDRKVSDLEFSEAELVGEEGDTSACCVVTESDPELEVEYRESREPDLGPAGLDSASLSDADTVNPDEDSFSILGGDSPTGPDSLMHDLPPLFLHLTCSVRLRGQHSSVPVCSLPTCLGQVLSSLEGPPVGGRVPLRDLSITLDVFVLTLPLEVELPPASDPQHHRSTSESSASFPRSPGQPSSLRSDDGLGPPLPPPEEERHPGLSSLATPHRLAIESTMSEIRWLLEDEMVGALRRGGIPQSPALHRAAAHIHSSSGRSTCLRQAPPLSFVFGPERSLTQFKEEFRRLHLPGHVLLEDPDSGFFFVAVGQQPGGLHGEPPSSAWAWHNHEDRAEDAEGEVLTASPQVPGSLEDSECTPLISLPSLSQGGSQPGPSRGLSLMSSQGSVDSDHLGYDGGSSGSDSEGPGETLGEKALFTLRTPPGPAPPQPSLSVLPGPSLPDFWLIVRILQDRVEVYAHARSLNREDGGPGTECRHLQQLLVRCVGEICREVNQRLLLQDLHDSHVCNSLLVAESEEDLWRSEMPFHSRQRVVLPSDDYAADESCAPRGYLAATMQFVPGHFSCDVVWGTVIRVHSRLKMGPSMGVSRAIQALRSVLNAFSVVNRKNMFVYQERATKAVYYLRLLETSCSDRPWEGDTLTPSLALSRSQEPIYSEDSAAPRSPLDMASSRSSDAVRPVGQVDRHIQLLVHGVGQAGPEITDELVRVLRRRLDEATLDIITVMLVRNCKLTPADVEFIQPPGSLPSEVLHLVLPPSCRPWLPALAWYLRQNLLTFLHSPKYTDSNSRNHFQHPLPAQGGLPDLDIYLYNKPGGQGTGGKGVACITLAFVEEGGAPISLASWPPSSPGPPGPLQEEEFEQLTQVIRCPNTPDNSQAQDGSPQLRLDVWEKGNISIVQLEEKLRAAARQALADAIMELRLLPASLCTEDIPPGSLKSGPLETKSPACRASTFPSTPVSGEPVTPPSKAGRRSFWDMLSKTEAGDLGSPKTTDDIVLDRPEDTRGRRRHKTENVRTPGGSERAPGSDSGAQRQRRRTTQLEEGEVGTLHPVFAHVIQRWMGFMVQIGCASVSRSSTHMVSRFLLPSILSEFTTLVISMAGDTSVRVFEQHLGSEPGLFSPCFPGQLGPAPRPAAERHLLLLGRNFAQWRRPTQQAAKAVQRFEAGGDGSPGRGAPRQRLLLLEVTDKKLQLLTYNWAPDLGAALGRALIRLAQWQNARAHLISCLLSQKLGLFHHCGQLDFPVRDGKEPNPFLLPTMEVETLIRNASPPLSREQGRLSGSSRGGGSLSLDTFPFDEALRDITAARPSSTGGPAPRPPDPVTYHGQQFLEIKMTERKELERQMKMENLFVTWQQRSAPASMPISAGELETLKQSSRLVHYCATALLFDPAAWLHGPPETSAPSEGQRRLRPESGSGGRELPTSCESSDVPPPGAREEPWLKELSLAFLQQYVQYLQSIGFVLVPLRPPSPARSTSRLRAMAVLGTEGRGSFSCPKAKTEGSPKSTSTPVTTYHLQRALPGGIILMELTFQGCYFCVKQFALECSRIPMGQAVNSQLSLLFTEECDKVRDLMHVHSFSYDFHLRLVHQHVLGAHLVLRHGYHLTTFLQHFLAHHPDGPHFGRNHIYQGTLELPTPLIAAHQLYNYVADHASSYHMKPLRMARPGGLEHNEYALVSAWHSSGSYLDSEGLRHQDDFDVSLLVCHSAAPFEEQGEAERHVLRLQFFVVLTSQRELFPRLTADMRRFRKPSRLSLEPEAPGSLVGSPGEASGIMLAPGPAPLFPPLAAEVGMARARLAQLVRLAGGHCRRDTLWKRLFLLEPPGPDRLRLGGRLALAELEELLEAVHAKSIADIDPQLDCFLSMTVSWYQSLIKVLLSRFPQSCRHFQSPDLGTQYLVVLNQKFTDCFVLVFLDSHLGKTSLTVVFREPFPVQPQESESPPAQLVSTYHHLESVINTACFTLWTRLL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2A9C3-1", "uniprot_id": "SZT2_MOUSE", "id": "A2A9C3-1", "name": "KICSTOR complex protein SZT2", "aln": "MASERPEPEVEEAGQVFLLMKKDYRISRNVRLAWFLNHLHQTVQATPQELLLQSEQELEVLSVLPPGWQPDEPVVPRPFLLVPSTRVTFLAWQYRFVIELDLSPSTGIVDDSTGEILFDEVFHALSRCLGGLLRPFRVPGSCINFQPEIYVTIQAYSSIIGLQSHQVLVQGCLLDPSQREAFLQQVYEQLCLFEDKVATMLQQQYEPQGQAEDQSPESGESLGRKVGVSMVTADLGLVSMIRQGILALQLLPSNSSAGIIVITDGVTSVPDVAVCETLLNQLRSGTVACSFVQVGGVYSYDCSFGHVPNVELMKFIAMATFGSYLSTCPETEPGNLGLTVYHRAFLLYSFLRSGEALNPEYYCGSQHRLFNEHLVSASSNPALALRRKKHTEKEVPADLVSTVSVRLREGYSVREVTLAKGGSQLEVKLVLLWKHNMRIEYVAVAPWPLEPEGPRGTRVEVTMEGGYDILHDVSCALRQPIRSLYRTHVIRRFWNTLQSINQTDQMLAHLQSFSSVPEHFTLPDSTKSGVPLFYIPPGSSTPVLSLQHSGSDSSHAQFAAYWKPVLSMDANSWQRWLHMHRLVLILEHDTPLPKHLHTPGSNGRYSTIQCRISHSSLTSLLRDWSSFVLVEGYSYVKLLSSAPDQPPSSFYMVRIISKTPCMVLRLGFPIGTPAQARHKIVSGLKEEILRLRFPHRVQSKEPTPKVKRKGLGGVGG-SSPSKSPPTLGPQQALSDRPCLVVLHKPLDKLLIRYEKLPLDYRAPFLLTLEPPGPLPLVSGRSASSSLASLSRYLYHRRWLWSVPSGLAPTLPLSATAQLLSVLTEVRLSEGFHFACSGEGIINMVLELPVQNEPLGQAAAEEKHTCVVQYILFPPHSTSTKDSFSTDDDNDVEVEALEGDSELNLVTEVWVEPQYGRVGPGPENWKHLQDLTYSEIPQALHPRDAACIGSLLTFEYLIQLCQSKEWGPLPPEPRLSDGLDQRGDTCVHEIPFHFDLLGLLPQCQQLQMFFLLLSREPEGVPLAEGPCPTNDMVLCLLHSCLGQELSDREIPLTPADQAAFLNEVLRRSLRDPGPEGPPVGGHAVAKDRAGNSTQASGDSTLPSQSVVIPGVLRSSISAQPPQWHCYARLLGPQHVFLTFLPATFSDVQHLTAYGLESSFQEETKPKLGDWSGAPSLKDPGATGTKATESQVPTLSVTLASDSAQDSGEPSTPSCQDLAANSGRQAPQTEGADGPRTRCPVYIYSCSLEALREQMVGLQPPQAPRDLIFRAQDLDHPSSSSAWMEPRCKEAATHCALLQEHAQRCFVRGLFRSLQQAQSVTCQDLLTAVDACEELLQEIDITSFLLALCGHTWGLPHAPPSPGPLSPGPFSSSIEEGPEPRERAILVSESSIETEDLSEPEFQSSRVSGNLDPGPEISLTDVCQLRGEAHDALHSLIQEKFLEISRLHFRTVPSNPHYFFYCPPSSRREDEGPRDTVDRKISDLEFSEAELVGEEGDTSACCVVTESDPELEVEYRESREPDLGPAGLDSASLSDADTVNPDEDSFSILGGDSPTGPDSLMHDLPPLFLHLTCSVRLRGQHSSVPVCSLPTCLGQVLSSLEGPPIGGRVPLRDLSITLDVFVLTLPLEVELPPASDPQHHRSTSESSASFPRSPGQPSSLRSDDGLGPPLPPPEEERHPGLSSLAMPHRLAIESTMNEIRWLLEDEMVGALRRGGIPQSPALHRAAAHIHSSSGRPTCLRQAPPLSFVFGPERSLTQFKEEFRRLHLPGHVLLEDPDSGFFFVAAGQQPGVLHGEPPSAAWAWHNHEDRAEDAEGEVLTASPQVPGSLEDSEGTPLISLPSLSQGGSQPGPSRGLSLMSSQGSVDSDHLGYDGGSSGSDSEGPGETLGEKALFTLRTPPGPAPPQPSLPVLPGPSLPDFWLIVRILQDRVEVYAHARSLSREDGGPGAECRHLQQFLVRRVGEICREVNQRLLLQDLHDSHVCNSLLVAESEEDLWRSETPFHSRQRAVLPSDDFAADESCAPRGYLAATMQFVPGHFSCDVVWGTVIRVHSRLKMGPSMGVSRAIQALRSVLNAFSVVNRKNMFVYQERATKAVYYLRLLETSCSDRPWEGDTLPPSLALSRSQEPISSEDSVAPRSPLDMASSRSSDAVRPVGQVDRHIQLLVHGVGQAGPEITDELVRVLRRRLDEATLDIITVMLVRNCKLTPADVEFIQPPGSLPSEVLHLVLPPSCRPCLPALAWYLRQNLLTFLHSPKYTDSNSRNHFQHPLPAQGGLPDLDIYLYNKPGGQGTGGKGVACITLAFVEEGGTPISLASWPPSSPGPPDPLREEEFEQLTQVIRCPNTLDSCSAQDGSPRLRLDVWEKGNISIVQLEEKLRAAARQALADAIMELRLLPASLCTEDIPPGSLKSGPLDTKSPACRANTFPCTPVSGEPVTPPSKAGRRSFWDMLSKTEAGDLGSPKTTDDIVLDRPEDTRGRRRHKTENVRTPGGSERAPGPDSGAQRQRRRTTQLEEGEVGTLHPVFARVIQRWMGFMVQIGCASVSRSSTHMVSRFLLPSILSEFTTLVISMAGDTSVRVFEQHLGSEPDVFSPCSPGQLGPAPRPAAQRHLLLLGRNFAQWRRPTQQAAKAVQRFESGGDGSPGRSAPRQRLLLLEVTDKKLQLLTYNWAPDLGAALGRALIRLVQWQNARAHLISCLLSQKLGLFHHCGQLDFPMRDGKEPNPFLLPTMEVETLIRNASPPLSREQGRLSGSSRGGGPLSLDTFPFDEALRDITAARPSSTGGPAPRPPDPVTYHGQQFLEIKMTERKELERQMKMENLFVTWQQRSAPASMPISAGELETLKQSSRLVHYCATALLFDPAAWLHGPPETCAPSEGQRRPCPESGSGSREVPTSCESLDVPPPGAREEPWLKELSLAFLQQYVQYLQSIGFVLVPLRPPSPARSTSRLRAMAILGTEGRGSFSCPKAKAEGSPKSTSTPVTTYHLQRALPGGIILMELTFQGCYFCVKQFALECSRIPMGQAVNSQLSLLFTEECDKVRDLMHVHSFSYDFHLRLVHQHVLGAHLALRHGYHLTTFLQHFLAHHPDGPHFGRNHIYQGTLELPTPLIAAHQLYNYVADHASSYHMKPLRMARPGGPEHNEYALVSAWHSSGSYLDSEGLRHQDDFDVSLLVCHSAAPFEEQGEAERHVLRLQFFVVLTSQRELFPRLTADMRRFRKPSRLPLEPETPGSLVGSPREASGMMLAPGPAPLFPPLAAEVGMARARLAQLVRLAGGHCRRDTLWKRLFLLEPPGPDRLRLGGRLALAELEELLEAVHAKSIADIDPQLDCFLSMTVSWYQSLIKVLLSRFPQSCRHFQSPDLGTQYLVVLNQKFTDCFVLVFLDSHLGKTSLTVVFREPFPVQPQDSESPPAQLVSTYHHLESVINTACFTLWTRLL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5T011-1", "uniprot_id": "SZT2_HUMAN", "id": "Q5T011-1", "name": "KICSTOR complex protein SZT2", "aln": "MASERPEPEVEEAGQVFLLMKKDYRISRNVRLAWFLSHLHQTVQATPQEMLLQSEQELEVLSVLPPGWQPDEPVVPRPFLLVPSTRVTFLAWQYRFVIELDLSPSTGIVDDSTGEILFDEVFHALSRCLGGLLRPFRVPGSCIDFQPEIYVTIQAYSSIIGLQSHQVLVQGCLLDPSQREVFLQQIYEQLCLFEDKVATMLQQQYDPQSQAEDQSPDSGDLLGRKVGVSMVTADLGLVSMIRQGILALQLLPSNSSAGIIVITDGVTSVPDVAVCETLLNQLRSGTVACSFVQVGGVYSYDCSFGHVPNVELMKFIAMATFGSYLSTCPEPEPGNLGLTVYHRAFLLYSFLRSGEALNPEYYCGSQHRLFNEHLVSASSNPALALRRKKHTEKEVPADLVSTVSVRLREGYSVREVTLAKGGSQLEVKLVLLWKHNMRIEYVAMAPWPLEPEGPRVTRVEVTMEGGYDILHDVSCALRQPIRSLYRTHVIRRFWNTLQSINQTDQMLAHLQSFSSVPEHFTLPDSTKSGVPLFYIPPGSTTPVLSLQPSGSDSSHAQFAAYWKPVLSMDANSWQRWLHMHRLVLILEHDTPIPKHLHTPGSNGRYSTIQCRISHSSLTSLLRDWSSFVLVEGYSYVKLLSSAPDQPPNSFYMVRIISKAPCMVLRLGFPIGTPAPARHKIVSGLREEILRLRFPHRVQSKEPTPKVKRKGLGGAGGGSSPSKSPPVLGPQQALSDRPCLVVLHKPLDKLLIRYEKLPLDYRAPFLLTLEPPGPLPLVSGRSASSSLASLSRYLYHQRWLWSVPSGLAPALPLSAIAQLLSILTEVRLSEGFHFACSGEGIINMVLELPIQNEPPGQAAAEEKHTCVVQYILFPPHSTSTKDSFSTDDDNDVEVEALEGDSELNLVTEVWVEPQYGRVGPGPGIWKHLQDLTYSEIPQALHPRDAACIGSMLSFEYLIQLCQSKEWGPLPPEPRVSDGLDQGGDTCVHEIPFHFDLMGLLPQCQQLQMFFLLLAREPEGVPFAEGSCPANDMVLCLLHSCLGQELSDREIPLTPVDQAAFLSEVLRRTCHVPGAEGPLLGVHGIPKEQAVGSTQATGDSAFTSLSVGLPETLKPLISAQPPQWRCYARLVNPQHVFLTFLPATFSDVQRLAACGLEGPPQEETKPKFGDWSGAPSLKDLGGTGIKATKSHVPVLSVTLASDNAQNQGELSPPFRRDLQAYAGRQASQTESADGPRTRCPVYIYSCSLEALREQMVGMQPPQAPRDLIFRTQFLDHPSPSSAWMEPRYKEAANHCALLQEHAQRCYVRGLFRSLQQAQSVTSQDLLTAVDACEELLQEIDITPFLLALCGHTWGLPHAPPSPGPLSPGPFSSSMEEGAEPRERAILASESSIETEDLSEPEFQSTRVPGIPDPGPEISLTDVCQLRGEAHGALHSVIQEKFLEISRLHFRTVPSNPHYFFYCPPSSRREDEGPRDTVDRKISDLEFSEAELMGEEGDTSACCVVTESDPELEVEYRESRESDLGPAGLDSASLSDVDTVNPDEDSFSILGGDSPTGPESFLHDLPPLFLHLTCSVRLRGQHSSVPVCSLPTCLGQVLSSLEGPPVGGRVPLRDLSVTLDVFMLTLPLEVELPTASDPQHHRSTSESSASFPRSPGQPSSLRSDDGLGPPLPPPEEERHPGLSNLATPHRLAIETTMNEIRWLLEDEMVGALRRGGIPQSPALHRAAAHIHSSPGRSTCLRQTLPLSFVFGPERSLTQFKEEFRRLHLPGHVLLEDPDSGFFFVAAGQQPGGSHGEPSSAAWAWHSHEDRAEGIEGETLTASPQAPGSPEDSEGVPLISLPRVPQGGSQPGPSRGLSLMSSQGSVDSDHLGYDGGSSGSDSEGPNDTLGEKAPFTLRTPPGPAPPQPSLSGLPGPCLPDFWLIVRVLQDRVEVYAHARSLIREDGGPGTECRHLQQLLVRRVGEICREVNQRLLLQDLHDSHVCNSLLVAESEEDLWRSETPFHSRQRAPLPSDDYAADESCAPRGYLAATMQFVPGHFSCDVVWGTVIRVHSRLKMGPSMGVSRAIQALRSVLNAFSVVNRKNMFVYQERATKAVYYLRLLETSCSDRPWKGDALPPSLALSRSQEPIYSEEASGPRSPLDMVSSRSSDAARPVGQVDRHIQLLVHGVGQAGPEITDELVRVLCRRLDEATLDVITVMLVRNCKLTPADVEFIQPPGSLPSEVLHLALPTSCRPWLPALAWYLRQNLLIFLHSPKYTDSNSRNHFQHPLPPQGGLPDLDIYLYNKPGGQGTGGKGVACITLAFVDEGGAPLSLALWPPSSPGPPDPLREEEFEQLTQVIRCPVVVDSSSAQNGAPRLRLDVWEKGNISIVQLEEKLRGAARQALADAIIELQLLPASLCTEDTPTGSLRNGSLETKSSAGRASTFPPAPVPGEPVTPPSKAGRRSFWDMLSKTECGDLGSPKTTDDIVLDRPEDTRGRRRHKTESVRTPGGAERAPGSDSGAQRQKRRTTQLEEGEVGTLHPVFARVAQRWMEFMVQIGCASVSRSSAHMVSRFLLPSILSEFTALVTSMAGDTSVRIFEQHLGSEPEIFGPCSPGQLGPSPRPAAERHLLLLGRNFLQWRRPTQQAAKAMQRFEPGGDGSSGRNAPRQRLLLLEVVDKKLQLLTYNWAPDLGAALGRALVRLVQWQNARAHLIFCLLSQKLGLFHHYGQLDFPVRDEKEPNPFLLPTMEVETLIRSASPPLSREQGRLSGSSRGGGPLPLDTFPFDEALRDITAARPSSVLGPVPRPPDPVTYHGQQFLEIKMAERRELERQMKMENLFVTWQQRSTPATMPISAGELETLKQSSRLVHYCATAMLFDPAAWLHGPPETSGPPDGQRRHRPESGSGSREAPTSCESLDVSPPGAREEPWLKELSLAFLQQYVQYLQSIGFVLVPLRPPSPARSTSRPRAMAILGTEGRGSFSCPKTKTDGSPKSTSSPVTTYHLQRALPGGIILMELAFQGCYFCVKQFALECSRIPMGQAVNSQLSMLFTEECDKVRDLMHVHSFSYDFHLRLVHQHVLGAHLVLRHGYHLTTFLRHFLAHHPDGPHFGRNHIYQGTLELPTPLIAAHQLYNYVADHASSYHMKPLRMARPGGPEHNEYALVSAWHSSGSYLDSEGLRHQDDFDVSLLVCHCAAPFEEQGEAERHVLRLQFFVVLTSQRELFPRLTADMRRFRKPPRLPPEPEAPGSSAGSPGEASGLILAPGPAPLFPPLAAEVGMARARLAQLVRLAGGHCRRDTLWKRLFLLEPPGPDRLRLGGRLALAELEELLEAVHAKSIGDIDPQLDCFLSMTVSWYQSLIKVLLSRFPQSCRHFQSPDLGTQYLVVLNQKFTDCFVLVFLDSHLGKTSLTVVFREPFPVQPQDSESPPAQLVSTYHHLESVINTACFTLWTRLL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "************************************.******** *** *********************************************************************************************:*********************************:**.****:********:*********::**.*******:**: *************************************************************************************************************.*****************************************************************************************.**********************:*********** *******************************************************:*************************** ******* *******************************************:*******************************************************.**********:*************** *********:****************************.** ********.*********************************************************************:************:***** *****:***************************:**:* ******************************************************************* **************************:*:********************::****** **********:***:****************:*******::**.**:************************..**:***.*****: **.**. :* *.:.*::* . ***:***::.: ** :* :. ********:*****:.*****************:*:* ** .. *******:*********** *.:* :*.:*:** ********.:*: ** *.* :*: * :****.***.**************************:************:* *****.******** ****.************:***************.****************:***.******************************:***.********.*****************:**.* *******************.****:********************************************:**********:****************************.**************.*********************:*::*******************************************:**********:*****:**********.*************************************************.** *******:**.***********************************.**.*****: *****************************************.***** ****.*:*****.******. ***.******.*** **** .****** :.****************************************.:****** ****************. ****.*********:************** *******:*******:*** *************************************** *******. *****:***********************************************************************************************:**:*.************ **:: .*******.*******.******************************** *********:********************************.**.**** ************* *********************.*********************************:***:*:*** *********.**:************** . *...**:*:*:*********************.**********:**:********** *.***:.*.*:***.* **.*** :**.***********************.*****************************.******:*****.*******:*******************:* **** **************:****************:** *********:********* :*.** ******:*****:********** ************:****.*****.**.***********.***********************:**.********** ************ ******:** ******************.********************.*.********************. **.*******************:**:*******************:**:************************:**************..*.:**** ******.** ****** **.********************************************** ****:*************:*::*******:********************:*****************************:************************************.***********:********************************************************* *************************************.*******************************************.**. ***:*** .*** ****::*****************************************************************************.***********************************************************************************:*******************************", "identical_positions": 3122, "similar_positions": 224, "identity": "90.97%" }, { "cls_id": "homologset.agr.RGD:1308617", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4A516-1", "uniprot_id": "D4A516_RAT", "id": "D4A516-1", "name": "Zinc finger protein 287", "aln": "MLASRKKVANSSRSQVLLMWKPDKIQNGPCNAEKQILTSRLLRDAETCRQNFRNFPYPDVAGPRKALSQLRELCLKWLRPEVHSKEQILELLVLEQFLSILPGEVRTWVNSQYPENSEEVVALVEDLAQIL-EEEAPQNSALPQEIPEEDPKH----ALETGWLNDLVTKESVTFNDVAVDITQEDWELMRPVEKELYKTVTLQNYWNMVSLGLTVYRPTVIPILEEPWMVIKEIVEGPSPEWETKAQACSPLKDFPKLKQDGTQTIKLEESCD--CEDGLERQPAYAFRKIHIDEDDFSLKSELSQE-DPTEECLSKYDLYRDNFEKHTNLIIQFDTQSDSKTLLYNESKPTFTNVSSGGVVHGKILPGDKPYSCNVCGKKFRKYPSLLAHRNNHAKDKSYECEECGKEFKHLSSLIAHQRMHTGEKPYECHQCGKAFSQRAHLTIHQRIHTGEKPYKCNDCGKDFSQRAHLTIHQRTHTGEKPYKCLECSKTFSHSSSLINHQRVHTGEKPYICNECGKTFSQSTHLLQHQKIHTGKKPYKCNECWKVFSQSTYLIRHQRIHSGEKCYKCTECGKAFAHSSTLIQHQTTHTGEKSYICNVCGKAFSQSANLTQHHRTHTGEKPYKCSVCGKAFSQSVHLTQHQRIHNGEKPFKCNTCGKAYRQGANLTQHQRVHTGEKPYKCHHCGKAFIYSSSLNQHRRTHTGERPYKCTHCNKDFSQRTCLIQHQRIHTGERPYGCRICGKSFTQSTNLIQHQRVHMGARHRNGQI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EQB9-1", "uniprot_id": "ZN287_MOUSE", "id": "Q9EQB9-1", "name": "Zinc finger protein 287", "aln": "-------MANSSLSQVLLMWKPGKIQKGPCSAEQQTLTSRLLRDTETCRRNFRNFPYPDVAGPRKALCQLRELCLKWLRPEVHSKEQILELLVLEQFLSILPGEVRTWVNSQYPESSEEVVALVEDLTQILEEEEAPQSSALPQDTPEDDPNHDPNPASQAGWLSDVVTKDLVTFNDVAVDITQEDWELMPPVQKELYKTVTLQNYWNMVSLGLTVYRPTVIPVLEEPWMVIKEIVEGPNPEWEPKAQAQCPAKHLPELKQDGTQTVKLEDSYDDDNDDSVESPPVCAFGMIHIDEEGFSVKSELSQE-DPTEEYLSKCDIYRVTFEKHTNLGVQFDTQSDDKTALYNESKPPFSNASSGGAVRGKILPGDKPYSCNVCGKQFRKYPSLLAHRENHAKEKAYECEECGKEFKHLSSLIAHQRMHTGEKPYECHQCGKAFSQRAHLTIHQRIHTGEKPYKCEDCGKDFSQRAHLTIHQRTHTGEKPYKCLECSKTFSHSSSLINHQRVHTGEKPYICNECGKTFSQSTHLLQHQKIHTGKKPYKCNECWKVFSQSTYLIRHQRIHSGEKCYKCTACGKAFAHSSTLIQHQTTHTGEKSYICNVCGKAFSQSANLTQHHRTHTGEKPYKCSVCGKAFSQSVHLTQHQRIHNGEKPFKCNTCGKAYRQGANLTQHQRVHTGEKPYKCHHCGKAFIYSSSLNQHRRTHTGERPYKCSHCNKDFSQRTCLIQHQRIHTGEKPYGCRICGKAFTQSTNLIQHQRVHTGARHRN---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HBT7-1", "uniprot_id": "ZN287_HUMAN", "id": "Q9HBT7-1", "name": "Zinc finger protein 287", "aln": "MLASSKRMNSSSRSQILLRWKSDKAQSGPYNVEKEILTSRFLRDTETCRQNFRNFPYPDLAGPRKALSQLRELCLKWLRPEIHSKEQILELLVLEQFLTILPGEVRTWVKSQYPESSEEAVTLVEDLTQIL-EEEAPQNSTLSQDTPEEDPRG--KHAFQTGWLNDLVTKESMTFKDVAVDITQEDWELMRPVQKELYKTVTLQNYWNMVSLGLTVYRPTVIPILEEPWMVIKEILEGPSPEWETKAQACTPVEDMSKLTKEETHTIKLEDSYD--YDDRLERRGKGGFWKIHTDERGFSLKSVLSQEYDPTEECLSKYDIYRNNFEKHSNLIVQFDTQLDNKTSVYNEGRATFNHVSYG-IVHRKILPGEKPYKCNVCGKKFRKYPSLLKHQSTHAKEKSYECEECGKEFRHISSLIAHQRMHTGEKPYECHQCGKAFSQRAHLTIHQRIHTGEKPYKCDDCGKDFSQRAHLTIHQRTHTGEKPYKCLECGKTFSHSSSLINHQRVHTGEKPYICNECGKTFSQSTHLLQHQKIHTGKKPYKCNECWKVFSQSTYLIRHQRIHSGEKCYKCNECGKAFAHSSTLIQHQTTHTGEKSYICNICGKAFSQSANLTQHHRTHTGEKPYKCSVCGKAFSQSVHLTQHQRIHNGEKPFKCNICGKAYRQGANLTQHQRIHTGEKPYKCNECGKAFIYSSSLNQHQRTHTGERPYKCNECDKDFSQRTCLIQHQRIHTGEKPYACRICGKTFTQSTNLIQHQRVHTGAKHRN---", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .** **:** **..* *.** ..*:: ****:***:****:*********:*******.*************:****************:**********:*****.***.*:*****:*** ******.*:*.*: **:**. * ::***.*:***: :**:************** **:*****************************:***********:***.****.**** * :.:.:*.:: *:*:***:* * :* :* .* ** ** .**:** **** ***** *** *:** .****:** :***** *.** :***.:..*.:.* * *: *****:***.******:******** *:..***:*:**********:*:**********************************************:******************************.********************************************************************************. ***************************:******************************************************* ****************:*********:.**************:***********..*:*******************:**.******:************** **:*** ", "identical_positions": 615, "similar_positions": 95, "identity": "79.87%" }, { "cls_id": "homologset.agr.RGD:1308618", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P0CAX8-1", "uniprot_id": "TGAP1_MOUSE", "id": "P0CAX8-1", "name": "T-cell activation GTPase-activating protein 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAATTAAVVAEEDTELR----DLLVQTLE------------------------NSGV---LNRIKAELRAAVF-------------------------------------------------------------------------------------------LALEEQEKV--EVKILVEFLIDNCFEIFGENIRTRSRITSDDSLEHTDSS--------DVSTLQNDSAYDSNDPDVEP---TSGAASPNRQLEGPTPTMAGLDTRGHRDTCESSSESSVSMVVRLKNSIVQQDRRFSEPNMSPSRECLVGPTSKQKLTRSEDSFTLSQDASCSEGDEAEDPFTEEVFPAVDSKPKRPVDLKIKNWTQGLASPQGHITKAFSRSSPGESLGSSPVPSPSCPKRNFFTRHQSFTTKTDKTKPQ--REIRKHSMLFSFASHKKVLPRTSSIGSEKSKDFSRDQLQKDLRKESQLSGRIVQENESEIQSQTSLGFSLSGTWALSVDNTFQLVDMRKPGSPPSYEEAIYYQTSGLTAYGGQTVG-----SMRSRMFKPSTAVPPVPSHHGGDLSEGTPG-----GHRLSSVTEHWTHSQTVHVS------IETQGRSELHQLRTVSESMQKAKLDCLGPQHSHLVFEADQLCCARESYI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B2RWW0-1", "uniprot_id": "TAGAP_MOUSE", "id": "B2RWW0-1", "name": "T-cell activation Rho GTPase-activating protein", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKLISSLDGSKTLNANNMETLIECQSEGDIKVPPLLTSCES--EDSICQLTEIKKRKKVLSWPSLMRKLSPSSDFSGSLEPELKVSLFDQPLSIICGENDTLPRPIQDILTILCLKGPSTEGIFRKAASEKARKELKEGLNCGVSVNLKQLPVHLLAVVFKDFLRGIPLKLLSCDLFEDWMGALEKPTEEDRIEALKQVAGGLPRPNLLLLRHLLYVLHLISKNAEVNKMDSSNLAICIGPNMLTLKNDQSLSFQAQKDLNNKVKILVEFLIDNCFEIFGENIRTRSRITSDDSLEHTDSS--------DVSTLQNDSAYDSNDPDVEP---TSGAASPNRQLEGPTPTMAGLDTRGQRDTCESSSESSVSMVVRLKSSIVQQDRRFSEPNMSPSRECLVGPTSKQKLARSEDSFTLSQDASCSEGDEAEDPFTEEVFPAVDSKPKRPVDLKIKNWTQGLASPQGHITKAFSRSSPGESLGSSPVPSPSCPKRNFFTRHQSFTTKTDKTKPQ--REIRKHSMSFSFASHKKVLPRTSSIGSEKSKDFSRDQLQKDLRKESQLSGRIVQENESEIQSQTSLGFSLSGTWALSVDNTFQLVDMRKPGSPPSYEEAIYYQTSGLTAYGGQTVG-----SMRSRMFKPSTAVPPVPSHHGGDLSEGTPG-----GHRLSSVTEHWTHSQTVHVS------IETQGRSELHQLRTVSESMQKAKLDCLGPQHSHLVFEADQLCCARESYI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZXG5-1", "uniprot_id": "D3ZXG5_RAT", "id": "D3ZXG5-1", "name": "T-cell activation Rho GTPase-activating protein", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVYAKTLNANNMDTLIECQSEGDIKVLPLLTSCES--EDSICQLIEVKKRKKVLSWPSLMRKLSPSPDFSGSLEPELKVSLFDQPLSIICKENDTLPRPIQDILTILCLKGPSTEGIFRKAASEKARKELKEELNCGGSVNLNQLPVHLLAVVFKDFLRGIPLKLLSCDLFEDWMGALEKPSEEDRIEALKQVADRLPRPNLLLLRTLVYVLHLISKNAEVNKMDSSNLAICIGPNMLTLKNDQSLSFQAQRDLNNKVKILVEFLIDNCLEIFGENIPTHPRITSDDSLEHTDSS--------DVSTLQNDSAYDSNDPDVEP---ANGVASPCRQLEGPSTTVAGMDTRGPRNTCESSSESSVSMVARLKSSIGQQDRRFSEPNMPPSRECFVGPITKQKLTRSEDSFVLPQEASCSEGNEAEDPFTEEVFPAVEGKPMRPVDLKIKNLTQGLASPQGPANKAFSSFSAGESLDSSPVPSPSCPKRNFFTRHQSFTTKTDKTKPQ--REIRKHSMSFSFASHKKVLPRTSSIGSEKSKDFSRDQLQKDLRKESQLAGRIIRENESEIQSQTNLGSSLSGTWALSVDNTFQFIDVRKPGSPPSYEEAIYYHTSGLTAYSGQTVG-----SMRARMLKQSMAVPPVPSHHEGELSEGIPG-----GHRSSSVTEHWTQSQTVHVS------VETRGRSELHRLRTVSESVQRAKLDYLGQQRSHLVFEVDQLRCAKESYI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N103-1", "uniprot_id": "TAGAP_HUMAN", "id": "Q8N103-1", "name": "T-cell activation Rho GTPase-activating protein", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKLRSSHNASKTLNANNMETLIECQSEGDIKEHPLLASCES--EDSICQLIEVKKRKKVLSWPFLMRRLSPASDFSGALETDLKASLFDQPLSIICGDSDTLPRPIQDILTILCLKGPSTEGIFRRAANEKARKELKEELNSGDAVDLERLPVHLLAVVFKDFLRSIPRKLLSSDLFEEWMGALEMQDEEDRIEALKQVADKLPRPNLLLLKHLVYVLHLISKNSEVNRMDSSNLAICIGPNMLTLENDQSLSFEAQKDLNNKVKTLVEFLIDNCFEIFGENIPVHSSITSDDSLEHTDSS--------DVSTLQNDSAYDSNDPDVESNS-SSGISSPSRQPQVPMATAAGLDSAGPQDAREVSPEPIVSTVARLKSSLAQPDRRYSEPSMPSSQECLESRVTNQTLTKSEGDFPVPRVGSRLESEEAEDPFPEEVFPAVQGKTKRPVDLKIKNLAPGSVLPRALVLKAFSSSSLDASSDSSPVASPSSPKRNFFSRHQSFTTKTEKGKPS--REIKKHSMSFTFAPHKKVLTKNLSAGSGKSQDFTRDHVPRGVRKESQLAGRIVQENGCETHNQTARGFCLR-PHALSVDDVFQGADWERPGSPPSYEEAMQGPAARLVASESQTVGSMTVGSMRARMLEAHCLLPPLPPAHHVEDSRHRGSKEPLPGHGLSPLPERWKQSRTVHASGDSLGHVSGPGRPELLPLRTVSESVQRNKRDCLVRRCSQPVFEADQFQYAKESYI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A7S8-1", "uniprot_id": "A0AB13A7S8_DANRE", "id": "A0AB13A7S8-1", "name": "", "aln": "MRRRGSYDGTTAPIQPHLRGLAQRRRSAPNLMLGKALGMSWSPIREEAQCQVAVEQCPFVLGLTNEDSELILDECAQLTEGLKTRERHLFLISDALVIAKLKSNASYRLKHRVDLKDLWVCGFENDEEEENEDTDVDLRTSIVLAWSSSLCLVAFRLPELRDHWLQTLHRKTVEARLLAGSTSPPPSVLMKVLSGNTTNKTLSGDGMDSDLLVDSNG---KNSALSKELHNQEAHAQQPIGENGGKKSFKIPFKLKRSSTSPSVTAHPESSTKNLLFGRNL----QDDTALPKPIAEILLLLFRKGPVTEGVFRVSCNSKNLHTLRNQLNSGAEVDMDALPVTLLVGLLKIFLRELPGGLLMSEHYESWIGALEKERTEEVQSELRGMAEKLPKANSLLLQHLLCLFHHISQRSETNKMDAKNLAVCIAPTLLHR-----DSQPLDVDVVEKVTKLIQFLTENCCEIFGHDILTLFGDLEDRKATDKSDSASLMSPDISFEVHQHDSAYDSTDPDADCDCVEAESYEEGMMAHGSLGLSKKGRSDIQSCSSDAIFDTFTKTFSRRSSEPSILSTLPITGLRELARSHDDFSTEKEHFDNQPLKKQNSDDSFLLPNRSENRRSLKKLAGSFNMDLPIIVSSPTSKIGSCPSFCSSDSSSSNHSEQSKTPSP-LPSPAN--PRKTQSTRHASFMIKSRHNHAQGDQEVTRRSLSMRAKSLGNFTFNRSSLKKGDS-------QKEVVFPCETLQEDSQNETENPDE-------LVRRRRPLSAIEVFQQVDSRMPCSPPSYEQALQTGVHQAPP------------QYREMTVQHARELGKKSRPISMNDNLLDIYK----VNESTECLETFTESIQLDKP-----------QLVTFRQRAMSESVSQLKHEKVSRRCSQPVFEEFSY--AKESYV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1Q8C7-1", "uniprot_id": "F1Q8C7_DANRE", "id": "F1Q8C7-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKVLSGLGVPKSLTQNSMDPISMPATTVPLNTGLSLCQQTNGNLASISHTGNMNINRRRWRSIFRRVQKKNKDLYHAN-SEHTKNTLFGRALSEICQKDGSPPEPIMDILILLQRKGLHTEGVFRRAGNTKAVKEIKAQLNDGIEVDLKEHPVIWLADLIKDFLRHLPGGLLMSEKYKDWMDAMEKEDEDQKCAEIKMLINTLPVPNIQLLKHLIVLLFLISEKADTNKMVSTNLATCVSPNLLQT-----DSN---IEKMEEVTKLTAFLIDNCSRIFGDDALTLYEDSDEDELSDNQD---------SFSSHHHDSAYDSNDPDADT-------------YKGSCSDMDSIKSGVEEKAQEPEEPWTTQLLIRRRSEPTFN-------FTQTVQQHLSSSQTEVDFHEKQLKKQISDDCIVFRAGN-----------SFGKRCGLARSSASRTTSRGCSYCSSSSLESCFSSASESSIHNSPSPLP--SSKKNIQRKHSFPTPNRSETPR------KRSQSMKSAHLRSRTVFGRSGSTKRA-------IERTLRESETLPEVLTPQPE---------------PRRLSSDEVFQQVDSRIPSSPPSYEQAVQNNSPAALS------------CCRSLTVQDARCLSKQTCSGSRSS--------------SEETLDFSSGLADIHNR-----------DNAEACCDGMSGSSSCLR----QRSSSESMYEEH----IRESYV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .. : . * : : * * :. . . :: : . :*. * ** :** .***.: . .: . .... ... ::******.***.: . . : : : .. . * .. :. : : .. . . . :. . . . .: . * . . :. *: ** . . ::* : . * . : . : . * : ** :.** * . * ******:*: . * .: : . . : . :. :* * . : *. ::* :***:", "identical_positions": 50, "similar_positions": 104, "identity": "5.35%" }, { "cls_id": "homologset.agr.RGD:1308619", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4A6L5-1", "uniprot_id": "D4A6L5_RAT", "id": "D4A6L5-1", "name": "", "aln": "MLKERLEMAEDPQQQMGAPVVKLEKELPWGRGGEDSSPEAFRLRFRQFRYQEAAGPQEALRELQELCRRWLRPELHTKEQILELLVLEQFLTILPRELYTWIREHSPDSGKALVAMVEELMGSTEAKAVGEKRVSRPFSVPCHAQGEQLVTALGGGSWQSGIHLGPVEVKPEWGIPQGEGVQSLGPSTAEQLSQGPGDGTQAFQEQALPILHVGSGLPTVSARDQEIAAGFLAATSQGLGPFKDMTLGFPEEEWRHVAPAQIDCFGEYVDSQDCGAPPGAGSKEKEAKPQQEDLKRAFVGLTSDGFGEAAIQVPVPGGTCEQEPGGSGTSVPGLPAPQPG-VPLPEALSAHSSFWKPFQCPECGKGFSRSSNLVRHQRTHEEEKAFGCVECGKGFTLREYLTKHQRTHLGKRPYVCGECWKTFSQRHHLEVHQRSHTGEKPYKCADCWKGFSRRQHLLVHRRTHTGEKPYTCECGKSFSRNANLAVHRRAHTGEKPYGCQVCGKRFSKGERLVRHQRIHTGEKPYHCPACGRSFNQRSILNRHQKTQHRQEPPVQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6NSZ9-1", "uniprot_id": "ZSC25_HUMAN", "id": "Q6NSZ9-1", "name": "Zinc finger and SCAN domain-containing protein 25", "aln": "MLKEHPEMAEAPQQQLGIPVVKLEKELPWGRGREDPSPETFRLRFRQFRYQEAAGPQEALRELQELCRRWLRPELHTKEQILELLVLEQFLTILPREFYAWIREHGPESGKALAAMVEDLT----------ERALEAKAVPCHRQGEQEETALCRGAWEPGIQLGPVEVKPEWGMPPGEGVQGPDPGTEEQLSQDPGDETRAFQEQALPVLQAGPGLPAVNPRDQEMAAGFFTAGSQGLGPFKDMALAFPEEEWRHVTPAQIDCFGEYVEPQDCRVSPGGGSKEKEAKPPQEDLKGALVALTSERFGEASLQGPGLGRVCEQEPGGPAGSAPGLPPPQHGAIPLPDEVKTHSSFWKPFQCPECGKGFSRSSNLVRHQRTHEE-KSYGCVECGKGFTLREYLMKHQRTHLGKRPYVCSECWKTFSQRHHLEVHQRSHTGEKPYKCGDCWKSFSRRQHLQVHRRTHTGEKPYTCECGKSFSRNANLAVHRRAHTGEKPYGCQVCGKRFSKGERLVRHQRIHTGEKPYHCPACGRSFNQRSILNRHQKTQHRQEPLVQ", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****: **** ****:* ************** **.***:*********************************************************:*:*****.*:*****.****:* :*. .. :**** **** *** *:*:.**:***********:* *****. .*.* *****.*** *:********:*:.*.***:*..****:****::* **********:*.*********:***********:.*** ..**.********* ***** *:*.***: ****::* * * .*******.. *.****.** * :***: :.:******************************** *::*************** **************.***************************.****.******* ********************************************************************************************** **", "identical_positions": 449, "similar_positions": 63, "identity": "80.9%" }, { "cls_id": "homologset.agr.RGD:1308620", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D611-1", "uniprot_id": "OCSTP_MOUSE", "id": "Q9D611-1", "name": "Osteoclast stimulatory transmembrane protein", "aln": "MRTIRAATEHLFGLGWKFWRLGICKAVVPLQAAWKAFSQPVPASCNELLTQLLLCVSLASLIAGLAHHWLVSLQLYPLGPPALVTSLCGLFVFLSLGLVPPIRCLFVLSVPTLGSKQGRRLLLSYSAANLAVAVVPNVLGNVRAAGQVLSCVTEGSLESLLNTTYQLRQAARELGPASRAGSRSLTFEVEGKGSAFRLHMHTITQEILEDFSGLEFLAR-AALGTQRVVTGLFLLGLLGESAWYLHRYLTDLRFDNIYATRQLVRQLAQAGATHLLTSPPPWLLQTAQPKLSREELLSCLLRLGLLALLLVATAVTVASDYGAFLLAQAAVAWAQKLPTVPITLTVKYDASYKVLDFILFVLNQPPVESVFASMQRSFQWELRFTPHDCHLPQAQPPRVTAALAAGALQLLAGATLVLQAYAWRLRHTIAASFFPDQEARRLSHLQARLQRRHNQSDHLNK---QPGTMAT-RESRKP---------GQGTRTLESQG----------------PQAHDSLGPPYDLE--------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZHW3-1", "uniprot_id": "D3ZHW3_RAT", "id": "D3ZHW3-1", "name": "", "aln": "MRNSREAVQHLFGLGWKFWRLGICRAVVPLQAAWNAFSQPVPASRNELLTQLLLCVSLASLIAGLVHHWLVSLQLYPLGPPTLVTALCGLFVFLSLGLVPPIRCLFALSVPTLGSEQGRRLLLSYSAANLAAAVMPNVLANVRAVGRVLGCVTEGSLESLLNTTYQLRQAARELVPAGQAVSRSLTFEVEGNGSAFRLHTHTVTQQILEDFSGLEFLAR-AALGTQRVVTGLFLLGLLGESAWYLHRYLTDLRFDNIYATRQLVRQLTQAGATHLLAAPPPWLLQTAQSKLSQEELLSCLLRLGLLALLLIATAVTVASDYGAFLLARAAVTWAQNLPSVPITLTVKYDASYKVLDFILFVLNQPPVESVFASVQRSFQWELRFTSHNCHLPQAQPPRVTAALAAGALQLLAGATLVLQTYAWRLRHAIAASFFPAQEARRLSHLQARLRRRHDQSDHPDR---HANTVGT-RRPRKP---------GQGTSALESQG----------------SQAHDPLSASV-----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BR26-1", "uniprot_id": "OCSTP_HUMAN", "id": "Q9BR26-1", "name": "Osteoclast stimulatory transmembrane protein", "aln": "MPGHPGAAEQLVKTGWRSWHLGFWKALAPLQAAWDAFSQPVPASCGQLLTQLLLCASLAAAAAGLVYHWLASLLLYPPGPSAMVATVCGLLVFLSLGLVPPVRCLFALSVPTLGMEQGRRLLLSYSTATLAIAVVPNVLANVGAAGQVLRCVTEGSLESLLNTTHQLHAASRALGPTGQAGSRGLTFEAQDNGSAFYLHMLRVTQQVLEDFSGLESLARAAALGTQRVVTGLFMLGLLVESAWYLHCYLTDLRFDNIYATQQLTQRLAQAQATHLLAPPPTWLLQAAQLRLSQEELLSCLLRLGLLALLLVATAVAVATDHVAFLLAQATVDWAQKLPTVPITLTVKYDVAYTVLGFIPFLFNQLAPESPFLSVHSSYQWELRLTSARCPLLPARRPRAAAPLAAGALQLLAGSTVLLEAYARRLRHAIAASFFTAQEARRVRHLHARLQRRHDRHQGQQLPLGDPSCVPTPRPACKPPAWIDYRLDALRTESSEGEGKELWSCRDLSCNLGPVPPPCVTLGKSLHLSEPRFLHLHNDSIFTIDVTYFPRRDVVRMEGNTGHDRPG", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *.::*. **: *:**: :*:.******.********* .:********.***: ***.:***.** *** **.::*:::***:**********:****.******* :**********:*.** **:****.** *.*:** **************:**: *:* * *:.:* **.****.:.:**** ** :**::******** *** *************:**** ******* *************:**.::*:** *****:.**.****:** :**:*****************:****:**:*: *****:*:* ***:**:**********.:*.**.** *::** . ** * *:: *:*****:*. * * *: **.:*.***********:*::*::** ****:******. *****: **:***:***:: : : ... : * * . ** . * : *.:* . . .*. . ", "identical_positions": 318, "similar_positions": 112, "identity": "56.18%" }, { "cls_id": "homologset.agr.RGD:1308621", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JVZ7-1", "uniprot_id": "A0A0G2JVZ7_RAT", "id": "A0A0G2JVZ7-1", "name": "", "aln": "----MREPRKGFRARLARVLTGLGGRRERKGKISKEARLQDRPWGGQSCPDLAQSQGSTNDVSLKVQTQSHSEWDLRVRSHGGLWTQRRLHTSGRRSEPLGRLQRPAVG----------------SACDLAGYDSMEHECPAGTGSTEAIGGPSHPSRPESASPSLKQGSPGAPCQHPQHGAPEVLLKPELPGNLEDAPLLPRPDSFLTAAGAKGKPDTSGSAQSEPEPLHTRLCVRRTRYHITVTLQGCG-------------------------------------PAPGEEGKEPARPAPHPCGPEESRGWQEPPQKLRPITGYPINPPGEPPPRVPQHQGSKAQQERRVGWEPGFPHSREPVHRVAGASRVLLEPNMEGTTGSSARAEARVVSATLTWRQRPPAQEESRHRFHKVSLVSGARTEAPQEDVFEHSFRRE-EVNGFVKKEEEIVNCQGPREESGPMNFQSHGPIFSKKYIPPPKEKRPTMRLQEAADWGDGG----PQAPRTEPPGMGSMARTELLVPLPGPREPSPHPNVGVTSG--GSRNREEWRVTRTVR-TTTTTVVGGHVDRQVSSSVSVGPSVSGEALPRGRN-----------------------VTRTIRAVVVSPRAEGSPSRSQALEVLSNLVPAERIPPASRIPRLTMFTSR-------------------------------------GSGLGGTVGNTLGPPPETSPAELKTESSAPAPVGVPEVAHPPQNIDIPAAQLIQDQGGVSDARTVESSRLQRTSSPVLFPN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QTSQSQDRAPSSPKPQPCASS--PAHSPEQPVAPARLKAQASPHVLP-SVKEKFAGLP---------------------------VAPVPPMTG-IEVTKPEAPPNPSSPRRKAVPSSQSPCAPASPKDKFVQGPENRPSSALTQEEVFPGPRVPAHSHSP-----------------------------------------------------------------------------------------------------------------------------------------KEVLQARGAPIPSSSMPTTAVQDAEGGPSIKKEVGQDPQNSP------------------------------------------------------PRSLPCKETVEGPTAPGPLTPKQDVLVQESPGNSLSSPTPEECFQSPAVPLAPPSSEAKKPLSLEGSQAPEPMKAEASTESQLIPDSTEGTVPSEPS--------------REEDEAALTADLEIFLDTLRSMEPPEILRTHRLPRAPRSSYLAMYATLPAIEEDQ-LGPCVLGPSPQEGPSLEEEEE-------ELENPYLSDDEKLQ--RRQEKAAPGPSLDPHPSRPAKVTCSPMEMMKKLVAGQ-------GPEPQPSNRPTSRLGGSLLFG----------------------------------------------------------------NLVPANKDASALEPLGTKLSALPPHGAPGVRKVPGQLPLLCSGGP-PPEKPAPIQP-----------------------PEGWSPALKTQGKLNTRPGKVILFSEPGCQGRGREVWEDVADASAWAS--VASIRVIRGCWILYEQPEFRGQKLLLPEGDVELRALASTWSLQ---------------------------------GIGSLKRAVRDYCTPRISLFSEEGLKGKPVTLMGDLKDSQGLERPLQVASATVTAGLWLLYPKPFFEDTPCILEPGEYPTLEAWGTSGLSVGSLKPMRLGCPSVEKPGEPKAVVYEAPDFQGQSWEVSGDIYNLQQPED-SQSPQLTSVGSLRILGGCWVGYEKEGFRGHQYLLEEGEYADWSHWGGYDELLTSLRVIRTDFGDPAVVLFEDMDFQG-----HRVEVSSALPDVELAQHGPNTQAIHVLSGVWVAYEQVGFSGEQYILEKGVYRNCDDWGSGNCALGSLQPVVQVGESDLHFVSKIQLFSGPNFLGDHISFEDDQASLPASFHPQSCRVHGGSWVLFEDKNFEADQHIVSEGEYPTLTAMGCLASTVLGSLRKIPLHFSEPSLSLFGLECFEGKEIELTGEVRSLQAEGFNNHVLSVRVQGGVWVVCEHSDFRGRQWLVGSCEITNWLTYSGTQRVGSLYPIKQRRAYFRLWNAALGGFLSVPDHVEDMKAGRVVVSEPRAGGSCIWYYEEGLLKNQVAPTMSLQVIGPPSPGSKVVLWAESRLPRQTWSISELGHICSQMFEGQILDVKGGRGYDRDHVVLWEPTKDRPSQIWTVHVL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A2I3BQG2-1", "uniprot_id": "A0A2I3BQG2_MOUSE", "id": "A0A2I3BQG2-1", "name": "", "aln": "----MREQRRGFRARLAQVLTGLGGRRKRKGKISKEARLQDRPWGSQSCPDLAQGQGSTNDVSLKVQTQSHSEWDLRVRSHGGLWSQKRLHSSGRQTDPLGRLQRPAVG----------------SACDLAGYGSMEHECPALAGSAEAIGGPSHPSGPEPASPSLKQGWSGTPCQHSQHSA------PELPGNLEDAPLWPHPESFLTAARAKGKPDTPGPAEPEPEPVHTRLCVRRTRYHITVTLQGCG-------------------------------------RAPGEEGREPARPAPHPCGPEESRGWQEPPQELRPITGYPINPPGEPPLKAPQHQGSKVRQKLLVGWEPGIPHSREPVHRVT--------RKMEETAGSPARAEARVVSATLTWRQRPPVQEESRHRFHKVSLVSGARMEAPQ-DVFEHSFRRE-EVNGFVKKEEETVNCQGSGEEPGSTNFQSHGPIFSKKYIPPPKEKRPTVRVQEAADWGDGG----PQAPRTELPGMGSMARTELLVPLPGPREPSPHPHVGVASG--GSRNREEWRVTRTVRTTTTTTVVGGHVDRRVSSSVSVGPSMSGETLPRGRN-----------------------VTRTVRAVVVSPRAEGSPSRSQALEVLSNLMPAERIPPASRIPRLTMLTSR-------------------------------------GSGPGGTVGTTLGQPLEISTTELKNSISALAPVGVPAVDSPAQNIDIPVAHPIRDQGGVSDARTEESSRLQGASS-VLLLN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QTSQSQVPASSSPKPQTCAAS--LTQSPEQPVVPAHLEAQSTPHVLP-AVKEKFTGLS---------------------------TVPVPPTAK-GEVTVPEPPPSPSSPRRKAAPSSQSPCAPASPKSKFVPDPENVPSSALTQKEVYPCPSVPAHSHIP-----------------------------------------------------------------------------------------------------------------------------------------KEVLQAHGAPKTSSSRPTTVVQNAEGGPSIKKEVGQYPQNSPS-----------------------------------------------------PCSVPCKETVESPTFPAPLPPKQDEVVRDSPGNFLSSPTPKGSFQSP--PFAPSSSEAKESLSLEGSPASKPMGAEVSTGSQTIPDSTEGKVPSEPS--------------EEEDEAALTADLEIFLDTLRSMEPPEILRTHRLPRAPRSSYLAMYATLPAIEEDQ-LGPCVPGPGPQERPVLEEEEEEVEEEEEELENPYLSDDEKLR--RRQEKAGPRPSLGLHPPTPAKVTCSPMEMMKKLIAGQ-------GPEPQPSNRPTSRLGGSLLFG----------------------------------------------------------------NLVPANKDAPALEPLGTKLSALPPHGAPGVKKVPGQLPLLCSGRP-PPEKPAPIEP-----------------------PEGWSPAPKTQGKLNTRPGKVILFSEPGCRGRGREVWGDIADASAWDP--VASIRVIRGCWILYEQPEFRGQKLSLPEGDVELRALACAWSLQ---------------------------------GFGSLRRAVQDYCTPRISLFSEEGLKGKPVTLTGDLKDSQGLERPLQVASATVTAGLWLLYPKPFFEDTPYILEPGEYPTLEAWGTSGPSVGSLKPMRLGCPSVEKPGEPKAVVYEAPGFQGQSWEVSRDIYNLQQPED-SQSPQLTSVGSLRILGGCWVGYEKEGFRGHQYLLEEGEYADWSNWGGYDELLTSLRVIRTDFGDPAVVLFEDMDFQG-----HRVEVSSALPDVELAQHGPSTQAIHVLSGVWVAYERVGFSGEQFILEKGVYRNCDDWGSGNCALGSLQPVVQVGESDLHFVTKIQLFSGPNFLGDHISFEDDQASLPASFHPQSCRVHGGSWVLFEDKNFEADQHIVSEGEFPTLTAMGCLASTVLGSLRKVPLHFSEPSLSLFGLECFEGKEIELTGEVRSLQAEGFNNHVLSVRVKGGVWVVCEHSDFRGRQWLVGSCEITNWLTYSGTQRVGSLYPIKQRRAYFRLWNAALGGFLSVPDHVEDMKAGRVVVSEPQAGGSCIWYYEDGLLKNQMAPTMSLQVIGPPSPGSKVVLWAESRLPRQTWSINELGHICSQMFEGQILDVKGGRGYDRDHVVLWEPTKDRLSQIWTVHVL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N1P7-1", "uniprot_id": "CRBG2_HUMAN", "id": "Q8N1P7-1", "name": "Beta/gamma crystallin domain-containing protein 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEEAGGPMARAKARVVSATLTWRQRPPTQEEIKHGFHKVSLVSGAQMEAPQKEMFEFSRREEVEVNGFATQEEETVNCQGPRDTAGSKNFQSHGPIFSKKYIPPPKEKRPEGRLKEAVDQSDGS----RQAPRTEPPCVGAMARTELLVPLPGPREPSPHPGVGLTSG--SSRSLEEYRVTRTVR---TTTVVGGHVDRRMSSSVTVRPVSSGEALPRGRQ-----------------------VSRMVPPVVVGS-PPGSPSRSQAVKVLSNLVPAGHSPPASHLPRPTAGGPR-------------------------------------STGLGSTVGAALRQLPETGTAELK-DSSALASTGIPASAHLPKNQDAPAACPDRDQGRAPDARACELWQVLGAPSSTELPL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QTSQGQASVPSSPRLETHVPSPGLTHPAKQPVVPTHPGARLTPLVLPPKKKDGPVDPP---------------------------AATVLPMVRSEHVTVPGQPPAPSTTRRKDVPSPGGLSAPSSPRNKFVQNSENVPVLPFTQREVVKGPGAPAASSPTRKEVVQGSSASAASSPTWKEVVKGPGAPAASSPTQKEVVQGSSAPAALFPTWKEVVKGPGAPDASFPTWKEVVKGPGAPAASSPTQKEVVQGSGAPAALSTTPKEVVKGPGAPAASSPTQKEVVKGPCAPAASSPTQKEVVQGSGAPAALSPKSTEVVQGPKGSSSIQKEAVQGIAGSL------------------------------------------------------APPLTKEETVQGPIAPATSLPKQDKGVQDSEGSPISSLTQKEVVQDPDALPAPSSSVDRVSPSPGGTPAPVPTGAEASTESQLVSDPTEGKTCTETS--------------REEDEVALAADLEIFLDTLRSMEPPEILRTHRLPRAPRSSYLSMYATLPAIEEDQ-LGPWVLGPGPQEVPSLEEKEEE---EEEEPENPYLSDDEKLQ--RRQEKAGPSPSRDLHPARPTQVSCSPLEMMKKHVAGTKGPHSELGLELQGGSRPTSRLGGSLLFG----------------------------------------------------------------SLVPTAKEASTPEPLGTKLSALLPHGAPGLRKVPGQLPLLCSERSSPTEKLACSLP-----------------------LEGWSPALKTQGKLNTRPGKVIFFSESGCQGSGREVWGDIVDASGWAP--VASIRVVRGCWVLYEEPEFRGQKLVLPEGDMELRTPGTKWSPQ---------------------------------GIGSLRRVVWDYSTPEISLFSEEGLKGEQVKLTEALKNSQGLEKPLQVASATVSAGLWLLYPKPLFEDTPYILEPGEYPTSEAWGTSDPSVGSLKPMRLGCPSVEKPGEPRAVVYEAPGFQGRSWEVSRDIYNLQQPED-SQSPHLASVGSLRVLGGCWVGYEKEGFRGHQYLLEEGEYPDWSHWGGYDELLTSLRVIRTDFGDPAVVLFEAMDFEG-----HGVEVSKALPDVELVQHGPSTQAIHVLSGVWVAYQEVGFSGEQYVLEKGVYRNCEDWGAGNSTLASLQPVLQVGEHDLHFVSKIQLFSRPDFLGDHFSFEDDQAALPASFRPQSCRVHGGSWILFDETNFEGDQHILSEGEFPTLTAMGCLASTVLGSLQKVSLHFSEPSIFLYGLECFEGKEIELSREVRSLQAEGFNNHVLSVRIKGGIWVLCEHSDFRGRQWLVGSCEITNWLTYSGTQRVGSLYPIKQRRVYFRLWNAALGGFLAVPDHVEDMKAGRVVVADPQAGGSCIWYYEDGLLKNQMAPTMSLQVIGPPSPGSKVVLWAESRLPRQTWSISESGHICSQMFEGQILDVKGGRGYDRDHVVLWEPDEDRASQIWTIHVL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AL91-1", "uniprot_id": "A0A8M3AL91_DANRE", "id": "A0A8M3AL91-1", "name": "", "aln": "MEKKSSSSRRTLKSLFSRSEVNLSEHEPKTDSNGGSFRLFKWKKKKKSESSEDNPNTDRAESADGDIQDGEEQNKHKTALFGRSKKGKRSYSETDLHKPKGFIGSLTWGRKKKQNRDRVQDLTSNSDISGVKDHISEQEEFDNHKETEQIQACVEAVRSAPEPPCASDQSQSQHVLSDQSTLSEEDAGFMPTAQESKAIPYIDSSDSDAYQTPPDSPNISSDAQAQPDTQYGKLSAQNSITSETSEYYICPGTDMKTAACTDTSTARISHDNVVSQKRSHLEHGEYSNAASLTQESYISRPESTDSSIHESSSLFIPKSPVFSIPESSFSSDPQNPTASIPQVSSSSDPQLSTSSIPESSFSSGPQISTSSIPQSTSTSVPQISTSSIPQSASTSVSQISTSSVPDSSSVSVPQIFISSVPQSSSSSDPQISTSLIPEFSSSSDPQIFTSSILQSTSTSVPQISTSSIPQSSSSSVPQISTSSIHQSSPTSVPQMSTSSIPQGSSSSVPQISTSSIPQSSSSSVPQISTSSIPQSSPTSVPQISTSSIPQGSSSSVPQISISSIPQSSTNSVPHSSTPLVHESSSSYIPQSSTSTMHDSFNSDSTMTQSFSTNTNSAFNLPEDSFSHPADTISYEDSHTTSANVRNKSFIDSNVINSDPSSPTTDICESDHVSSKPYVIVSSTLCSSRIKGNRIKTDRKPSSSNTNVSESDVTVHSTADSGSREETPPESSCVTISKESHATDNYSSLAYATDSEKHNPAQPVLPENESNIPLSPSARAYTIIKSTKVVTFDLSGPSDHISFDHSHRSLSNNEPDSDVETLTEILDHEGQDNNQTDTDSSAKASSGFPNHTIPSMSLTSYPPLHLDVSDQMFSSQSLKAKTEKQQKTSRACEDQEKCLQDASITEDTKLQKVSEECGMLKKKEDDVLIETEKQQKTFRACEDQEEYPQHASTQSLDPVDRINQNKSNAEITEATTLHKALEKVAMVEEKRDELYTKMEKQQKTFRAYEDQEGYLQDASTQRFTEKSIGESETNAERMTTTDDATSVTEDTKLQKVSEEFAMVKKKEDDVLMETEKQQKTFRAYKDHEEHLKDISAHRFIEKSVDQDKSNAEIKVSTKLHKALEKFAMVEKQRDDLHEETEKQQKTSRTYEDREACLQDASTQRFIEKSVDQNESNAEITEATKPHKALEKVAMVEKKTDELHMGTEQLKTSRAYEDREEYAQDASTQRLESIDQINQNKSNAERTTTRNDAISILDNELNQIIEATKLHKASEDSPMLKKMSNESHMDQISSAVETEACRGAGVLTGQAEPQIPSLSTPKPAIPVHQEHVPEECTPAPPFSELLKVSLTDSSMQSQSHLENLPLPLGLHQYNTEITILEDTAGCKHHSSTDKNTHGGYIDTLSRTLGSESQDCSIEELSGAYSTKQTFTHSNDSKQEEVKADGDTISLWNQISESTSDTERKEETDDLADQTASDCLTPGERIVHATVPSTVIEHNQVLNTVMNSGVSVLNTKLNPPSSPRDGRDDGVVFRKVSLVKNELPEPSRASPELQRRFQALQDKTERSDYTHSYEKAVYTSHFHSPETEVTHYSGGRGREELSLPGERLQIIPTHSQLDPEPALFIVEADDSEVFQAMRVELHHSPTSTEPPLLNSEMDNLVDTLKSMDRPLRQRVQRAPSN------APFSSLPPIEEDAPVSPSITPLSPPFSPVHEPKSMLNGSSGLDFGFNWSSTKDMRSPLTMMKEQQFGDAQNRGLSLPLRASALSSIVMRRSSLNDLSPEDGSAKPLINGASSSSRLENSFFFQPSENGASSRSIFRAASLPDIGSGADRISSAAKSTDSLVGSRFERFSYLTSPSNSLSGIAEASRISVAPFAQSQSAESQSFSHKSTSELYRSLPSETLLKSPPSLSIQRSSSLDGGFLINDNLQVNQKPEPEPERNLLLKYRAFPDAYLTKEKEHGKLNPRPGKMIIYDKPGFTGERIEVRGDVVDATPWEFTDTISVRVIRGGWVFYEKPDFKGEKIALDEGEMELTDPFRPAEEEEEADLQNGGESHGEIVNDGEEQQENKPHRTRKFSIGSIRRAVRDYSVPEISLFPEENAEGKKVTFRDTSEDARIFGFPIKANSIIINAGLWLVFAEPFFQGVPRVLEVGGFPSPSAWGVTHPYVGSLHPLKIGEPRVENLYEPRLVLYEKPYFTGKSREIYSSMRDFLSRADKQQTLFMFSAGSLKVTGGCWVGYEKEGFRGNQYLLEEGEYHDWRVWGGVNSELRSVRVIQSDLSEPQLVLFAMPEQESEQDEERTFDVTEAVADVELFGFGINTRSIQVLSGAWVAYSHVDFSGNQYVLEKGFYNNCGDWGSGDNRICSLQPILTAPSDGPILRNEVLLYSEPDFLGSCRVCHHNQDALPESLMVRSCRVVGGSWVLYGEEKFSGSMYVLSEGDYPNLSSMGLPADSRVRSVRAVPVSFCVPSVSLFGLECFEGREVTIDTQISSMQEEGFNTQFLSVRVNTGCWVLCEHSNYRGRQFLLEPIEITNWLKFSSMSCIGSLYPVRQKQRPFRIRNKQTGHCVSVQGGVEDMKTGRVLVSEQVEGMSDIWLYQDGLIKNKLARSMSLQVMGNVESGAKVVLWTETRVPVQTWSAQMSGAIASLTFPGMVLDIKGGKTYDKEHLVIREENEEQPSQQWELEFV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : .. .:: : ** * . . . : * . *.: :. : . . : : *... : .. . . ... .* ..: . . . :.. . .: . :*. * . :. * .: : .:: .. .*:. * :. :* .* . :: *.:* . . .** : * * .:: . : .:: .: *.. : : **:: : .*:: : . .: . * * . . :. . * . .:: : . . .::. . : : . : :.. . : :*.: * : :. . : ::.* . *. : . * : . ... .:. . ::.*.. . . *: .*: * ..* .* . . :* ::. * . . : ....: . .. . * .. .: :* : . . : : .: . : : . . : . . .* ** .:.: . :: * . : * :::: ::***:**: * *.:* * : :::**.**** :.* : .* * * :. : : * .: :: : . . * :.:. . :*:: . . . .:*** .*::* .:.* :. .: . :: *: : : ..: . * *. . . : :.: . * :****.****:*::.:.* * ** *:.**: * . *:**:** *::**:*:*:*:*: * **::** . : .:**::*.* **..*.****.**. :*: *.: :::: : *::. * :.*****::.:*:*:..* :** * :*: .***.: ****:*:::* * **: **: *:** * * *:* *: .: :: . * .*: : *.***:: **************:********* ** *** :. * *:***::*:.:* :*** : :. : .:*:.*:.**** .* .*::*:****.****..*.***:*::****.*.** ***:*: : ****:: . . . : .:: *:* *:***. ..:* :** *: :**** ****:*: : :*... :::***::*.*::** *.: : *:: :.: *. **: *:*******:*: : :: *:* ****.:.****:: * **:****::****:*: . ******.:*. . :*****::*:: **: * * ::* . *****:***:*:: * * ** *::**:**::* :*****:* ..*:*****:*:*:* **** . * *.* * * :**:***: **::*:*: * ::: ** * :..:", "identical_positions": 382, "similar_positions": 510, "identity": "14.23%" }, { "cls_id": "homologset.agr.RGD:1308622", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZXY2-1", "uniprot_id": "D3ZXY2_RAT", "id": "D3ZXY2-1", "name": "PDZ domain-containing protein 8", "aln": "-----MGLLLMILASAVLGSFLTLLTQFLLLYRRQPEPRADEAARAGDGFRYLKPVPGLPLREYLYGGG--------------AEEPAAGSSEA------GASTTPTPDSPAPPTL---------ETCYFLNATILFLFRELRDTALARRWVTKKIKVEFEELLQTKTAGRLLEGLSLRDVFLGDTVPYIKTIRLVRPVVASGTGEPDEPDGDALPATCPEELAFEAEVEYNGGFHLAIDVDLVFGKSAYLFVKLSRVVGRLRFVLTRVPFTHWFFSFVEDPLIDFEVRSQFEGRPMP-QLTSIIVNQLKKIIKRKHTLPSYKIRFKPFFPYQALQGFEEDEDL-IHIQQWALTEGRLKVTLLECSRLLIFGSYEREANVHCTLELSSGVWEEK-QRSSIKTVELIKGNLQSVGLTLRLVQSTDGYAGHVIIETVAPNSPAAIADLQRGDRLIAIGGVKITSTLQVLKLIKQAGDRVLVYYQRPVGQ---SNQGAMLQDSLGQLEEN-FLSSSCQPGYEEEAAGLPVD--SETRDLDSEFEDLAGDVR-----VQTELKEETQP-LSHSPKRTPTTLSIKPLGAISPVLNRKLISGIHPPPQKLPSKEGNKPSTLKTSEATEAAQ-VSKP-QVPTFKPPVPPRPQGRVPLPPTDTSAQAD---PETTEKPEKVLLPPPPADKPAEKQVKSVDHGEDVAAGKQ---------PPAKQEVVKDAPSESSAPTKDPSDDHQMWESSEVLYRNKVGKWSRARASCVFDIEACHRYLNIALWCRDPFKLGGLICLGHASLKLEEVALGCLATSNMEYLSKFRLEPPAPKAMVTRTALRNLSMQKGFNDKFCFGDITIHFKYLKEGEPDHQIVPSVEKERELH----------VVEE-----------VSTLPKEDHFVGQMSLSENKHSFQDTQFQNPTWCDYCKKKVWTKAASQCMFCAYVCHKKCQEKCLAETPLCGATERRVDRTLKSLRLEGQDPLLGLPPRVEMEANKSVN-KTTGLTRHIINTSSRLLNLRQVSKTRLAEP----GTDLVEPSPKHTPNTSDNEGSDTEVCGPNSPSKR-GNSAGIKLTRKEGGLDDSVFIAVKEIGRDLYRGLPTEERIQKLEFMLDKLQNEIDQELEHNNSLVREEKETNDTRKKSVLSASLAKSGERLQALTLLMIHYKAGIEDIETLENLSLDQHSKKMNKYTEDTEEDL------DSEISQLIDSQPFSNISDDLFGPSESV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B9EJ80-1", "uniprot_id": "PDZD8_MOUSE", "id": "B9EJ80-1", "name": "PDZ domain-containing protein 8", "aln": "-----MGLLLLILASAVLGSFLTLLAQFLLLYRRQPEPRADEAARAGDGFRYLKPVPGLPLREYLYGGG--------------AEELAACSSEA------GASSTPTPDSPAPPTL---------ETCYFLNATILFLFRELRDTALARRWVTKKIKVEFEELLQTKTAGRLLEGLSLRDVFLGDTVPFIKTIRLVRPVVASGTGEPDDPDGDALPATCPEELAFEAEVEYNGGFHLAIDVDLVFGKSAYLFVKLSRVVGRLRFVLTRVPFTHWFFSFVEDPLIDFEVRSQFEGRPMP-QLTSIIVNQLKKIIKRKHTLPSYKIRFKPFFPYQALQGFEEDEEL-IHIQQWALTEGRLKVTLLECSRLFIFGSYDRETNVHCTLELSSGVWEEK-QRSSIKTVELIKGNLQSVGLTLRLVQSTDGYAGHVIIETVAPNSPAAMADLQRGDRLIAIGGVKITSTLQVLKLIKQAGDRVLVYYQRPAGQ---SSQ-----DSLGQLEES-FLSSSCQAAYEEDAAGLSAD--TENRDLDSEFEDLASDVR-----VQTELKEETQP-LSHSPKRTPTTLSIKPLGAISPVLNRKLISGIHPPPQKLPSKEGNKPSTLKTSETTEAAQ-VSKP-QGPTFKPPVPPRPQGRVPLPPTDTSAQAD---PEAPEKPDKVLLPPPPADKPAEKQVKSVDQGEDVAAGKQ---------SSAKQEGVKDLPSESSAPTKDSSDDPQMWESSEVLYRNKVGKWSRTRASCVFDIEACHRYLNIALWCRDPFKLGGLICLGHVSLKLEEVALGCLATSNMEYLTKFRLEPPTPKAMVTRTALRNLSMQKGFNDKFCFGDITIHFKYLKEGEPDHHIVPNVEKEKELH----------LVEE-----------VSTLPKEEHFVGQMSLSENKHSFQDTQFQNPTWCDYCKKKVWTKAASQCMFCAYVCHKKCQEKCLAETPLCGATERRIDRTLKNLRLEGQDPLLGLPPRVEIEANKSVN-KTTGLTRHIINTSSRLLNLRQVSKTRLSEP----GTDLVEPSPKHTPNTSDNEGSDTEVCGSNSPSKR-GNSAGIKLMRKEGGLDDSVFIAVKEIGRDLYRGLPTEERIQKLEFMLDKLQNEIDQELEHNNSLVREEKETNDTRKKSVLSAALAKSGERLQALTLLMIHYRAGIEDIETLENLSLDQHSKKMNKYADDTEEDL------DSEISQLIDSQPFSNISDDLFGPSESV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NEN9-1", "uniprot_id": "PDZD8_HUMAN", "id": "Q8NEN9-1", "name": "PDZ domain-containing protein 8", "aln": "-----MGLLLMILASAVLGSFLTLLAQFFLLYRRQPEPPADEAARAGEGFRYIKPVPGLLLREYLYGGGR-------------DEEPSGAAPEG------GATPTAAPETPAPPTR---------ETCYFLNATILFLFRELRDTALTRRWVTKKIKVEFEELLQTKTAGRLLEGLSLRDVFLGETVPFIKTIRLVRPVVPSATGEPDGPEGEALPAACPEELAFEAEVEYNGGFHLAIDVDLVFGKSAYLFVKLSRVVGRLRLVFTRVPFTHWFFSFVEDPLIDFEVRSQFEGRPMP-QLTSIIVNQLKKIIKRKHTLPNYKIRFKPFFPYQTLQGFEEDEEH-IHIQQWALTEGRLKVTLLECSRLLIFGSYDREANVHCTLELSSSVWEEK-QRSSIKTVELIKGNLQSVGLTLRLVQSTDGYAGHVIIETVAPNSPAAIADLQRGDRLIAIGGVKITSTLQVLKLIKQAGDRVLVYYERPVGQ---SNQGAVLQDNFGQLEEN-FLSSSCQSGYEEEAAGLTVD--TESRELDSEFEDLASDVR-----AQNEFKDEAQS-LSHSPKRVPTTLSIKPLGAISPVLNRKLAVGSHPLPPKIQSKDGNKPPPLKTSEITDPAQ-VSKPTQGSAFKPPVPPRPQAKVPLPSADAPNQAE---PDVLVEKPEKVVPPPLVDKSAEKQAKNVDAIDDAAAPKQ---------FLAKQEVAKDVTSETSCPTKDSSDDRQTWESSEILYRNKLGKWTRTRASCLFDIEACHRYLNIALWCRDPFKLGGLICLGHVSLKLEDVALGCLATSNTEYLSKLRLEAPSPKAIVTRTALRNLSMQKGFNDKFCYGDITIHFKYLKEGESDHHVVTNVEKEKEPH----------LVEE-----------VSVLPKEEQFVGQMGLTENKHSFQDTQFQNPTWCDYCKKKVWTKAASQCMFCAYVCHKKCQEKCLAETSVCGATDRRIDRTLKNLRLEGQETLLGLPPRVDAEASKSVN-KTTGLTRHIINTSSRLLNLRQVSKTRLSEP----GTDLVEPSPKHTPNTSDNEGSDTEVCGPNSPSKR-GNSTGIKLVRKEGGLDDSVFIAVKEIGRDLYRGLPTEERIQKLEFMLDKLQNEIDQELEHNNSLVREEKETTDTRKKSLLSAALAKSGERLQALTLLMIHYRAGIEDIETLESLSLDQHSKKISKYTDDTEEDL------DNEISQLIDSQPFSSISDDLFGPSESV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B5N0-1", "uniprot_id": "A0ACD6B5N0_DANRE", "id": "A0ACD6B5N0-1", "name": "", "aln": "-------MIYLILLSAFSGAVVTLLLQLLLLYRRSPEP----VART---VQYVKVVPDPALKDYFSSQQADSAPQQPDSPSPVSKQPEAASPKQQETPVPGSSPKQQPSSPPPPSLSDPQHSSKAETCDFLNAIILFLFRELRDTPVVRHWITKKIKVEFEELLQTKTAGRLLEGLSLRDVSLGNSVPVFKTARLMKPVAVNED-------------NMPEELNFEVDLEYNGGFHLAIDVDLVFGKSAYLFVKMTRVAGRLKLQFTRMPFTHWSFSFLEDPLIDFEVKSQFEGRPLP-QLTSIIVNQLKRVIKRKHTLPNYKIRYKPFFPFQVQPPLMSSCDLDISIRDTLLVEGRLRVTLVECSRLFILGSYERETYVHCTFELSSDEWREK-TRSSIKETEVIKGPSGSVGMTFRHVPASDGDTVHVSIETVTPNSPAALADLQRGDRLIAIGGVKVTSSVQVPKLLKQAGERVIVLYERPVRHHVPTGGLGMLQETLGPMEEPSYLPQ--PGGYEEDPAPITTMDISENKDNDSEFEELNVESKTAAAPVTIDTKEDFLLSVNQSPKKTVANL-AKPLGSISPILNRRLN---LQSPLKTQPKESPKPPTLKNAEPSEQPQRPTVPPPPPPARPPVPPRPHIKVTSASSEAQSLVEGNEPTVEKSPEKTQPNTGNGEKPVEKIPVKPPEPKPVSKHPEPTEDILNIPATNKQDSAKDKISESSSNTRDSVDEQGLWESSETMYRNRTARWN--KASVIFEVESNHKFLNVALWCKNPFKLGSLLCLGHVSLRLEHLALECISTSSAEYQSTFRLCAPEPRASVSRTALRSLSTHKGFNEKLCYGDVTLNFTYLADGESDLSSG-LMERERKGS----------LQEEDLKDREKEREQVLMVTRDEPIYSGMQIGEMRHNFQDTQFQNPTYCEYCKKKVWTKAASQCMICSYVCHKKCQEKCLLEHPYCVAASDRRG--------------------ADPEAKSTINRATTGLTRHIINTSSRLLNLRQVPKARLAEQVADMGSGVVEPSPKHTPNTSDNESSDTETYTGASPSKQPAGSSGSKLVRKEGGLDDSVFIAVKEIGRDLYRGLPTDERSQKLELMLDKLQQEIDQELEHNNSLSTEERDTIDSRRKTLITAALAKSGERLQALTLLMIHYRAGIEDLESVESTSPSEQHGFPKAKSEGLEEALMGTEVYDSDMCSPVDVQMLDEITEEQICVEALP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VYR9-1", "uniprot_id": "PDZD8_DROME", "id": "Q9VYR9-1", "name": "PDZ domain-containing protein 8", "aln": "MEIPISNILLLCLIFLLIGGVVMILLQYLIFIKFSNLPDESEEQKQAN-AKYTLPLNIKQTARNLKRLS---------------NSGLGGGAGN------GCENHQESLRRASALVS-------------LNFVMQFLFHEFKNSNRVRKWFYRKLSIELDELISKTTTGKLLDKLTIKELELGDQFPDVKSLSVHNVELDKDE-------------QRIENLDLLLDINYVGNFTTSIDADMVLGKKGSITLRVKQLSGMARLQFTRKPYTHWSISFLGDPELILDIESKYQGRQMQSNITNLISNQIRKAVRRKHTLPNYKLRYKPFFHWTAEEDASDCDIQ---------PNGLLTVKLAELSRLMG---YPGASETYCTITLAPVPFIEASQRDSRNVLISLDVFIHKAKNQQIGIVFKQSGSQVVRIESVLPNTPACKSNLLAGDVLVAIEGRPVTTIQQIAKVVKTLQATVFSLRIERIIP-----------------------------------GIIRNDAILEDFEKYEDIGDLPSSYP--------------------------------------------------------------CQPKLETDEAATADP--------------TPKHLVVKPSLSGTPTNSPKK---SNLIAKAIKKTMSRESGDKDRDKDKDK-DKDKDKDKDKD-------------KDKDKDKDKDKG---KEEVEEPVNYFYQHSTIDCPFSPLIHMEDVCSFQLDNSSRFLNVCVFGKS---AGESVLLGYNNVQIGQILVECSETSLNQCLKQISLNPASLQAVKT----HPLSNQSGFNPNLCFGDILFGFSWMGNPNLTVGDVPIKSTSKSQSPARNPLAGDRVASEDQSQFLKLTSSMADSSTSGESSSGTTAAPRAHDFVRTHFHRATQCDFCGKKIWLKDAMQCQECSMCCHKKCIVKCQMAT-VCGPVDCTGSIPATSSTPSMASRPEFTITQADNPQIVDSSTGATPFDETSAASGGDQGQIQSPTASGLDVHR-SSLTGMLAQGIKRQASNLDIPGIVSSLTGSGQQVNS--KSLPPSPQHTPSRKSSIVEEATPALQQNPFESVTQHLEALPLDCPELSFEQVIVITEPIIRHTRNEDLMNLAKSTSKLLYAALP-PDERVAKINELLTKLKVALDAETEGYTLMNDAEKATESSPWKSDRSDE------RVQALSIIMLYLCTGLQHAQGVVLQ--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : * . *..: :* * ::: : . * : :* : : :. . .. *. . ... ** : ***:*:::: .*:*. :*:.:*::**:...*:*:**: *::::: **: .* .*: : . . *:* : :::* *.* :**.*:*:**.. : :::.:: * :: :** *:*** :**: ** : :::.*:::** : ::*.:* **::: ::******.**:*:**** : . . :* * *.* * ***: * : .:**: *:. : * *.* : :. .. : .:. : * **:* **:**. ::* ** *:** * :*: *: *::* *: . . : * : .:: :* . . *:. * : .* : : . . : : . . . : :* :* . . : :: ** .:.. :: :: : .. . . *::: ::**:.:: :. * : **: .::: .: : * ** : . : * .. :* : : ** :.*** ::*:**: : *.:: : : . .:. : .* : . . . *.* *:*:..* *::* **:* * * ** *: ***** ** * ... . .: . :* : . :.. :::. . : * :.:: . *: ... * . :. . : * . :. . .. * *. : :: :..:. . . *: .::: * . *: . . ..:: *:*. ..**: :. *: : :..:: . . . . .. .. : . : : . ", "identical_positions": 173, "similar_positions": 336, "identity": "13.86%" }, { "cls_id": "homologset.agr.RGD:1308623", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZPP0-1", "uniprot_id": "D3ZPP0_RAT", "id": "D3ZPP0-1", "name": "Zinc finger protein 668", "aln": "MEVEAAEAKSPGPCYKRSGRRYKCLFCTKTFPNAPRAARHAATHTTTDCTEEVNEVQPKVDAEPKAEEASGDKVSGSVAKPRPYACPLCPKAYKTAPELRSHGRSHTGEKPFPCPECG-------RRFMQPVCLRVHLASHAGELPFRCTHCPKAYGTLSKLKIHQRGHTGERPYACTDCGKSFADPSVFRKHRRTHAGLRPYSCERCGKAYAELKDLRNHERSHTGE--RPFLCSECGKSFS-RSSSLTCHQRIHAAQKPYRCPACGKGFTQLSSYQSHERTHSGEKPFLCPRCGRMFSDPSSFRRHQRAHEGVKP-----YRCEKCGKDFRQPADLAMHRRVHTG--------DRPFKCLQCDKTFVASWDLKRHALVHSGQ-------RPFRCEECGRAFAERASLTKHSRMHSGERPFHCNACGKSFVVLSSLRKHERTHRSNETTGAAPQQELVLGLALPVGVVGEGSAAPVAGAGIGDAPAGLLGLPPESGSVVATQWQVVGMTVEHVECQDAGVGEAPSTLGDAGEVGGEETDEKPPQFVCRECKETFSTLTLLRRHERSHPELRPFPCTQCGKSFSDRAGLRKHSRTHSSVRPYSCSQCPKAFLSASDLRKHERTHPVPIGTPIPLEPLVALLGMPEEGSA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K2R5-1", "uniprot_id": "ZN668_MOUSE", "id": "Q8K2R5-1", "name": "Zinc finger protein 668", "aln": "MEVEATEARSPGPCYKRSGRRYKCLFCTKTFPNAPRAARHAATHTPTDCTEEVREAQPKVDTEPKAEEASGDKVSASVAKPRPYACPLCPKAYKTAPELRSHGRSHTGEKPFPCPECG-------RRFMQPVCLRVHLASHAGELPFRCTHCPKAYGTLSKLKIHQRGHTGERPYACPDCGKSFADPSVFRKHRRTHAGLRPYSCERCGKAYAELKDLRNHERSHTGE--RPFLCSECGKSFS-RSSSLTCHQRIHAAQKPYRCPACGKGFTQLSSYQSHERTHSGEKPFLCPRCGRMFSDPSSFRRHQRAHEGVKP-----YRCEKCGKDFRQPADLAMHRRVHTG--------DRPFKCLQCDKTFVASWDLKRHALVHSGQ-------RPFRCEECGRAFAERASLTKHSRMHSGERPFHCNACGKSFVVLSSLRKHERTHRSNETTGAAPQQELVLGLALPVGVVGEGSAAPVAGAGVGDAPAGLLGLPPESGGVVATQWQVVGMTVEHVECQDAGVGEAPSTLGDAGEVGGEETDEKPPQFVCRECKETFSTLTLLRRHERSHPELRPFPCTQCGKSFSDRAGLRKHSRTHSSVRPYSCSQCPKAFLSASDLRKHERTHPVPIGTPIPLEPLVALLGMPEEGSA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96K58-1", "uniprot_id": "ZN668_HUMAN", "id": "Q96K58-1", "name": "Zinc finger protein 668", "aln": "MEVEAAEARSPAPGYKRSGRRYKCLSCTKTFPNAPRAARHAATHGPADCSEEVAEVKPKPETEAKAEEASGEKVSGSAAKPRPYACPLCPKAYKTAPELRSHGRSHTGEKPFPCPECG-------RRFMQPVCLRVHLASHAGELPFRCAHCPKAYGALSKLKIHQRGHTGERPYACADCGKSFADPSVFRKHRRTHAGLRPYSCERCGKAYAELKDLRNHERSHTGE--RPFLCSECGKSFS-RSSSLTCHQRIHAAQKPYRCPACGKGFTQLSSYQSHERTHSGEKPFLCPRCGRMFSDPSSFRRHQRAHEGVKP-----YHCEKCGKDFRQPADLAMHRRVHTG--------DRPFKCLQCDKTFVASWDLKRHALVHSGQ-------RPFRCEECGRAFAERASLTKHSRVHSGERPFHCNACGKSFVVSSSLRKHERTHRSSEAAGVPPAQELVVGLALPVGVAGESSAAPAAGAGLGDPPAGLLGLPPESGGVMATQWQVVGMTVEHVECQDAGVREAPGPLEGAGEAGGEEADEKPPQFVCRECKETFSTMTLLRRHERSHPELRPFPCTQCGKSFSDRAGLRKHSRTHSSVRPYTCPHCPKAFLSASDLRKHERTHPVPMGTPTPLEPLVALLGMPEEGPA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VQY7-1", "uniprot_id": "Q9VQY7_DROME", "id": "Q9VQY7-1", "name": "", "aln": "MENVCQCCKVRPGLSVKRGGSLPKTLCLQCLHMDTFGTKHKGPRPETQINDKVHLEMSINGEDGLPEHPLYPEVQLVVKEEDALIKKKVIEENHIHNEEIIGASNIVDVEVHENHRANNDVILIQDSFAEEVILEDHPANND-VIIIQDSVAEEELPVIKEEAIEGEDLQGEYFIITECLEEPAIGSCRVCLEQSDNLTNIFDDAHQYGIPIATILSQYTGMPVEKGDSFSEYICVTCLDVVKNAFDDLESKENTIQMYRQPKEEIIDIDSIPVK-NKPVDYEVTGKPPHRCPQCPKIFLLAAKLQAHIRTHNETRTTEPPRLKCPMCPSIYMKRGCLEAHMWIHRASDERESELEPPYRCPHCPKLFLYSSFLEIHIQTHEDVSQRLSRKSSHKCAQCADVFSDVSSLKDHVKIHAGERTFKCPLCLMSFQEESNLKSHDCAHTRFKCHKCSKFFESQNYLDFHFKKS-HTTKGPFKCIKCQQTFQKRNGLKEHISSQVCVQFLRSKSPGQIFPCPKCPKKFSIEDNYQMHHATHKKVKTVIERHNCTQCKKSYQNKKLLTKHILSHNR-----CVHCSMSFTSKYLLEQHT----------CSQSYQLNGSRGRKNPNLNYNECEESNESDLEP-------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** . .: : * * : : . .::* ..: :: .::* . : .*.. :*. . : . : : * . . .. : . ... * : * *. * *.: : :: : . : .:.: *. .. ** :. ... . .: : ...: * . * : . . ..*: ::* * . .. ..* .::. : : . . :. :. : :*: *. **:* ::* .:.:: * *:*: .:. :* * . : : . * * :* . : *::* :* * *: * *: * .*.. ..:* :*. .*:: :**..* ::*:***.*:* * ** *.*:.*: :* : . * * : . . : .* :. ** . .. :..*: . : . * .. : .. ::.. :. * :**:::.. .** :* ** . *.:*. **:.: *.:*: *.:. : * . . : . : .. *** ", "identical_positions": 91, "similar_positions": 208, "identity": "14.02%" }, { "cls_id": "homologset.agr.RGD:1308624", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BZL1-2", "uniprot_id": "NEUR4_MOUSE", "id": "Q8BZL1-2", "name": "Sialidase-4", "aln": "---------------------------MGPTRVPRRTVLFQRERTGLTYRVPALLCVPPRPTLLAFAEQRLSPDDSHAHRLVLRRGTLTRGSVRWGTLSVLETAVLEEHRSMNPCPVLDEHSGTIFLFFIAVLGHTPEAVQIATGKNAARLCCVTSCDAGLTWGSVRDLTEEAIGAALQDWATFAVGPGHGVQLRSGRLLVPAYTYHVDRRECFGKICWTSPHSLAFYSDDHGISWHCGGLVPNLRSGECQLAAVDG----DFLYCNARSPLGNRVQALSADEGTSFLPGELVPTLAETARGCQGSIVGFLAPPSIEPQDDRWTGSPRNTPHSPCFNLRVQESSGEGARGLLERWMPRLPLCYPQSRS--PENHGLEPGSDGDKTSWTPECPMSSDSMLQSPTWLLYSHPAGRRARLHMGIYLSRSPLDPHSWTEPWVIYEGPSGYSDLAFLGPMPGASLVFACLFESGTRTSYEDISFCLFSLADVLENVPTGLEMLSLRDKAQGHCWPS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LTJ9-1", "uniprot_id": "A0ABK0LTJ9_RAT", "id": "A0ABK0LTJ9-1", "name": "Sialidase-4", "aln": "MGSVCGCVNLWSSSPTGSLVPCFYQKGMGPAHVPKRTVLFQRERTGLTYRVPALLCVPPRPTLLAFAEQRLSPDDSHAHRLVLRRGTLTRGSVRWGVLSVLETAVLEEHRSMNPCPVLDEHSGTIFLFFIAVRGHTPEAVQIATGKNAARLCCVTSCDAGLTWGSVRDLTEEAIGAALQDWATFAVGPGHGVQLRSGRLLVPAYTYHVDRRECFGRICWTSPHSLAFYSDDHGISWHCGGLVPNLRSGECQLAAVDG----DFLYCNARSPLGNRVQALSADEGTSFLPGELVPTLAETARGCQGSIVGFPAPPSIGPQDDRWLASPGNTPHSPCFDLRVRESLAEGARGFVEGWASRLLLCYPQSRG--PENHGLEPGPDGEKTSWSPELPMSSASVRQSSTWLLYSHPAGRRARLHMGIYLSRSPLDPHSWTEPWIIYEGPSGYSDLAFLGPVPGASLAFACLFESGTRASYEDISFCLFSLADVLENVPTGLEISSLRNKPQGHCWPS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8WWR8-1", "uniprot_id": "NEUR4_HUMAN", "id": "Q8WWR8-1", "name": "Sialidase-4", "aln": "---------------------------MGVPRTPSRTVLFERERTGLTYRVPSLLPVPPGPTLLAFVEQRLSPDDSHAHRLVLRRGTLAGGSVRWGALHVLGTAALAEHRSMNPCPVHDAGTGTVFLFFIAVLGHTPEAVQIATGRNAARLCCVASRDAGLSWGSARDLTEEAIGGAVQDWATFAVGPGHGVQLPSGRLLVPAYTYRVDRRECFGKICRTSPHSFAFYSDDHGRTWRCGGLVPNLRSGECQLAAVDGGQAGSFLYCNARSPLGSRVQALSTDEGTSFLPAERVASLPETAWGCQGSIVGFPAPAPNRPRDDSWSVGPGSPLQPPLLGPGVHEPPEEAAVDPRGGQVPGGPFSRLQPRGDGPRQPGPRPGVSGDVGSWTLALPMPFAAPPQSPTWLLYSHPVGRRARLHMGIRLSQSPLDPRSWTEPWVIYEGPSGYSDLASIGPAPEGGLVFACLYESGARTSYDEISFCTFSLREVLENVPASPKPPNLGDKPRGCCWPS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** .:.* *****:***********:** *** ******.*********************: ******.* ** **.* ********** * :**:******* ************:********:* ****:***.*********.*:**************** ***********:********:** *****:******** :*:******************** .***********.******:********.* *.:*.*** ********* **.. *:** * .* .. :.* :. *:*. *.* . . :. *.*. *.: * .** .*: **: **. : **.********.********** **:*****:******:************ :** * ..*.****:***:*:**::**** *** :******:. : .* :*.:* ****", "identical_positions": 334, "similar_positions": 78, "identity": "65.36%" }, { "cls_id": "homologset.agr.RGD:1308625", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R4I4-1", "uniprot_id": "TF2AY_MOUSE", "id": "Q8R4I4-1", "name": "TFIIA-alpha and beta-like factor", "aln": "-------------------------------------------------MAFINLVPKLYQSVIEDVIEGVRDLFAEEGIEEQVLKDLKKLWETKVLQSKATEDFFRNSTQVPLLTLQLPHALPPALQP-EASLLIPAGRTLPSFTPEDLNTANCGANFAFAGYPIHVPAGMAFQTASGHLYKVNVPVMVTQTSGRTEILQHPFQQVLQQLGQPLVIQTTVPTLHPCSLQAATEKSLRMEAVLQPPPILHPPPVDRTHVENAASDRRLLPGNE--------LRPQESSPYLSLPGVGFPPQAALTESSLEPVLGVSASLTQNLHSDPFSQGPPGPLHHHLLESQLQSLKDSIYGCDSTKQLRKAEEPSSLRVSEKNCTSERDLNIRVTDDDINEIIQIDGTGDNSSTEEMGSIRDADENEFPGIIDAGDLNVL-EEVDSVSNEDSTANSSDNEDHQINAPEEDPLNSGDDVSEQDVPDLFDTENVIVCQYDKIHRSKNRWKFYLKDGVMCFGGRDYVFAKAIGEAEW-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7F7R8-1", "uniprot_id": "F7F7R8_RAT", "id": "F7F7R8-1", "name": "", "aln": "MLAFSFSILGESSAPSGLAVAQQRAPAVQKRAWRLSATQAQTVGRRAASMAFVNLVPKLYRSVIEDVIEGVRDLFAEEGIEEQVLKDLKKLWETKVLQSKATEDFFRNSVQAPLFTLQLPHGLPPALQS-TASLLIPAGRTLQSFTPEDLN-ASCAANFAFPGYPIHVPAGMALQTASGHLYKVNVPVVVTQTSGRAEILQHPFQQVLQQLGQPSIIQTTVPTLHPCSLQAETEKSHRMETALQQPTVLHSTPVDRKHTENATSERRVLPGNE--------LRPQESTQYISLPGVGFPPQVALTESSLEPVLGASANLTQNLHGGPFTQGPPGTLRHHVLDTQLHSLRDRIYGCDSVKQLRKIEEPSSLRVSEKSCTSERDLNIQVTDDDINEIIQIDGTGDNSSAEEGGSIRDADENEFPGIIEAGDLKVLEEEVDSVSNEDSTANSSDNEDHQIDALEEDPLNSGDDVSEQDAPDLFDTDNVIVCQYDKIHRSKNRWKFYLKDGVMCFGGRDYVFAKAIGEAEW-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UNN4-1", "uniprot_id": "TF2AY_HUMAN", "id": "Q9UNN4-1", "name": "TFIIA-alpha and beta-like factor", "aln": "-------------------------------------------------MACLNPVPKLYRSVIEDVIEGVRNLFAEEGIEEQVLKDLKQLWETKVLQSKATEDFFRNSIQSPLFTLQLPHSLHQTLQSSTASLVIPAGRTLPSFTTAELGTSNSSANFTFPGYPIHVPAGVTLQTVSGHLYKVNVPIMVTETSGRAGILQHPIQQVFQQLGQPSVIQTSVPQLNPWSLQATTEKSQRIETVLQQPAILPSGPVDRKHLENATSDILVSPGNEHKIVPEALLCHQESSHYISLPGVVFSPQVSQTNSNVESVLSGSASMAQNLHDESLSTSPHGALHQHVTDIQLHILKNRMYGCDSVKQPRNIEEPSNIPVSEKDSNSQVDLSIRVTDDDIGEIIQVDGSGDTSSNEEIGSTRDADENEFLGNIDGGDLKVPEEEADSISNEDSATNSSDNEDPQVNIVEEDPLNSGDDVSEQDVPDLFDTDNVIVCQYDKIHRSKNKWKFYLKDGVMCFGGRDYVFAKAIGDAEW-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P52654-1", "uniprot_id": "TF2AA_DROME", "id": "P52654-1", "name": "Transcription initiation factor IIA subunit 1", "aln": "------------------------------------------------MALCQTSVLKVYHAVIEDVITNVRDAFLDEGVDEQVLQEMKQVWRNKLLASKAVELSPDSGDGS-------------------------HPPPIVANNPKSHKAANAKAKKAAAATAVTSHQHIGGNSSMSSLVGLKSSAGMAAGSG----IRNGLVPIKQEVNS-----QNPPPLHPTSAASMMQKQQQAASSGQG-SIPIVATLDPNRIMPVN---------------------------ITLP---SPAGSASSESRVLTIQVPASALQENQLTQILTAHLISSIMSLPTTLASSVLQQHVN---------------------------AALSSANHQKTLAAAKQLDGALDSSDEDESEESDDNIDN---------------------DDDDDLDKDDDEDAEHEDAAEEEPLNSEDDVTDEDSAEMFDTDNVIVCQYDKITRSRNKWKFYLKDGIMNMRGKDYVFQKSNGDAEW-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32773-1", "uniprot_id": "TOA1_YEAST", "id": "P32773-1", "name": "Transcription initiation factor IIA large subunit", "aln": "--------------------------------------------------MSNAEASRVYEIIVESVVNEVREDFENAGIDEQTLQDLKNIWQKKLTETKVTTFSWDN-----------------------------------QFNEGNINGVQNDLNFNLATPGVNSSE------------------------------------------------------FNIKEENTGNEGLILPNINSNNNIPHSG------------------------------------------------ETNINTNTVEATNNSGATLNTNTSGNTNADVTSQPKIEVKPEIELTINNANIT--------------------------TVENIDDESEKKDDEEKEEDVEKTRKEKEQIEQVKLQAKK----------------------EKRSALLDTDEVGSELDDSDDDYLISEGEEDGPD-------ENLMLCLYDKVTRTKARWKCSLKDGVVTINRNDYTFQKAQVEAEWV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ::*. ::*.*: **: * : *::**.*:::*::*..*: :*.. . . . . : . : . :: . : . . : . .: : * : . . : :. : * .. :: . .: :. . . *: . : ::: * * .: * :*:::* ***: *:: :** ****:: : .**.* *: :*** ", "identical_positions": 39, "similar_positions": 84, "identity": "7.39%" }, { "cls_id": "homologset.agr.RGD:1308626", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZRS3-1", "uniprot_id": "A0A8I5ZRS3_RAT", "id": "A0A8I5ZRS3-1", "name": "", "aln": "---MMAEQVKCASPVAGSGAGPGPVVNAELEVKKLQELVRKLEKQNEQLRSRAASAAAAPHLLLLQPPPPSAPPPAGACSPLTTHRAPASTTSPGP-GALGPAFPGTYCLPSPAPSLLCSL-QPADAPFVYSKPAAGFFA-GGGSPEPWTAGTPPGEAATPPLPPPTLLDEVEPLDLESLAAWSEDDDYTWLYIGSSKTFTLSEKSLSPLQWCRHVLDNPTPEMEAARRSLRFRLEQASRWRSLFSSPASLAFPYSPVARLSPYS------------------------------------------------------NGISTPSSSKTSNKAILTPERTGYTSRGSPLSPQSSIDSELSTSELEDDSISMGYKLQDLTDVQIMARLQEESLRQDCASTSGSVSRNSSTISLSSGKKGTCSDQEYDRYSLEDEEEFDHLPPPQPRLPRCSPFQRGIPHSQTFSSIRDCRRSPSS-QYFPSNNFQQPQYYSPQAQTPDQQPNRTNG-----DKLRRSMPNLARMPSTTAVS--SNLSSPVTVRSSQSFDSSLHGAG-----SGVSRVPSCIPSPGQIQHRVHSVGHFPVPIRQPLKATAYVSPTVQGSSSS------------MPLSNGTQLYSNTGIPTPNKAAASGIMGRSALPRPSLAINGSNLPRSKIAQPVRSFLQPPKPLSSLSTLRDGNWRDGCY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q68FF7-1", "uniprot_id": "SLAI1_MOUSE", "id": "Q68FF7-1", "name": "SLAIN motif-containing protein 1", "aln": "---MMAEQVKCASPVAASGAGPGPVVNAELEVKKLQELVRKLEKQNEQLRSRAASAAAAPHLLLLQPPPPSAPPPAGACSPLATHRAPASTTSPGP-GALGPAFPGTYCLPSPAPSLLCSL-QPADAPFVYSKPAAGFFG-GGGSPEPGTAGTPPGEAATPPLPPPTLLDEVEPLDLESLAAWSEEDDYTWLYVGSSKTFTSPEKSPSPLQWCRHVLDNPTPEMEAARRSLRFRLEQG--------------------------------------------------------------------------------------------------------YTSRGSPLSPQSSIDSELSTSELEDDSISMGYKLQDLTDVQIMARLQEESLRQDYASTSASVSRNSSSVSLSSGKKGTCSDQEYDRYSLEDEEEFDHLPPPQPRLPRCSPFQRGIPHSQTFSSIRDCRRSPST-QYFPSNNFQQPQYYPPQAQTADQQPNRTNG-----DKLRRSMPNLARMPSTAAAS--SNLSSPVTVRSSQSFDSSLHGAG-----SGVSRVPSCIPSPGQIQHRVHSVGHFPVPIRQPLKATAYVSPTVQGSSSSGSSGSSGGSGSGMPLSNGTQLYSTTGIPTPNKAAASGILGRSALPRPSLAINGSNLPRSKIAQPVRSFLQPPKPLSSLSTLRDGNWRDGCY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8ND83-1", "uniprot_id": "SLAI1_HUMAN", "id": "Q8ND83-1", "name": "SLAIN motif-containing protein 1", "aln": "---MMAEQVKCASAGVSSGAGSGPVVNAELEVKKLQELVRKLEKQNEQLRSRAASAAAAPHLLLLPPPPPAAPPPAG-LQPLGPRSPPAATATAAASGGLGPAFPGTFCLPSPAPSLLCSLAQPPEAPFVYFKPAAGFFGAGGGGPEPGGAGTPPGAAAAPPSPPPTLLDEVELLDLESVAAWRDEDDYTWLYIGSSKTFTSSEKSLTPLQWCRHVLDNPTPEMEAARRSLCFRLEQG--------------------------------------------------------------------------------------------------------YTSRGSPLSPQSSIDSELSTSELEDDSISMGYKLQDLTDVQIMARLQEESLRQDYASTSASVSRHSSSVSLSSGKKGTCSDQEYDQYSLEDEEEFDHLPPPQPRLPRCSPFQRGIPHSQTFSSIRECRRSPSS-QYFPSNNYQQQQYYSPQAQTPDQQPNRTNG-----DKLRRSMPNLARMPSTTAIS--SNISSPVTVRNSQSFDSSLHGAG-----NGISRIQSCIPSPGQLQHRVHSVGHFPVSIRQPLKATAYVSPTVQGSSN-------------MPLSNGLQLYSNTGIPTPNKAAASGIMGRSALPRPSLAINGSNLPRSKIAQPVRSFLQPPKPLSSLSTLRDGNWRDGCY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GEE3-1", "uniprot_id": "A0AC58GEE3_DANRE", "id": "A0AC58GEE3-1", "name": "", "aln": "MLFSSMDGLLFKPQMMADVNGNSKMMNAELEVKKLQELVRKLERQNEQLRTRANAANNCTSSVRLLAAPASA--------------CPAGPAGPDT----GSFHTGNYCIS-PSYSPSFGL---SDEHYPYFHPQS-------------------VTGADEEDEDATVMDEVEKLDLHALLSIDGESEYSWLYV-SPKAKLFSHALLSPLQWCRHVLDNPKPEVELAKRSLCYKLDQAKRWRGVLSSCVSSSVLYSPLDGVSSLSSCSKPFTKPALTEQTEGLHMDYIYGFMCIRSAHFASGHRFYIADPPSPNQQKPLTGRNCLSLTERSPTFLYHTATQSNSHRQRPLSPQSSIDSELSASELEEDSVSMSYKLQDMTDVEVMARLQEESLRQEYASTTATATRRSASFSIHTAARRSMR----SEAELEEEEEYDQLSVPQPRLFRTASMQRSTSHTQNLSSMKDCRRSPSTPQYLNSLSFQQLHVANNSSPTAEAQSYRANTGQTTQDKLRRSMPNLLRAPSIPSVINVPNVSAPTGHIATTSSLSLLRNSQSFDSHNALAKIQSAIPSPGQLQQRVQSVGNFSMAARPPLKATAYVSPTIQSSNT-------------MASSASLSCISSSSIPLPSKPSTP-SSSRSALPRPASFVGTNGASRSKIGQPVRSLLTPPKSVSALSALRDGSWRDGCY", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . .. * . ::*****************:******:** :* .. : * ..*.:* **..: . . *. ..*.:*:. *: * .* .: : * :* : .* .*::**** ***.:: : :.:*:***: *.*: .. :************.**:* *:*** ::*:*. : * *************:****:**:**.*****:***::***********: ***:.:.:*.*::.*: :. : : .. .**:***:*:*. ***** * :.:**. .*:*.:**:::******: **: * .:** : .: *.: *. *:* ********** * ** .: .*:*:*. : * * *:.: ..:::: *.******:*:**:***:*.:. * ***********:*.*.. *. * . . *.:.** *.*.::. .*******: :. .. .****.*****:* ***.:*:**:****.******", "identical_positions": 244, "similar_positions": 167, "identity": "34.76%" }, { "cls_id": "homologset.agr.RGD:1308627", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q62203-1", "uniprot_id": "SF3A2_MOUSE", "id": "Q62203-1", "name": "Splicing factor 3A subunit 2", "aln": "MDFQHRPGGKTGSGGVASSSESNRDRRERLRQLALETIDIN------------KDPYFMKNHLGSYECKLCLTLHNNEGSYLAHTQGKKHQTNLARRAAKEAKEAP-AQPAPEQVKVEVKKFVKIGR--------PGYKVTKQRDTEMGQQSLLFQIDYP-EIAEG---------IMPRHRFMSAYEQRIEPPDRRWQYLLMAAEPYETIAFKVPSREIDKAEGKF----------FFLQFHFKMEKPPAPPSLPAGPPGVKRPPPPLMNGLPPRPPLPDALPPPPPGGLPLPPMPPTGPAPSGPPGPPQMPPPAPGVHPPAPVVHPPTSGVHPPAPGVHPPAPVVHPPTSGVHPPAPGVHPPTPGVHPPAPGVHPPAPGVHPPAPGVHPPTPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPPAPAVHPQAPGVHPPAPGIHPQAPGVHPQPPPGVHPAAPGVHPQPPGVHPSNPGVHP-APMPPMLRPPLPSDGPGNMPPPPPGN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AXT8-1", "uniprot_id": "SF3A2_RAT", "id": "Q6AXT8-1", "name": "Splicing factor 3A subunit 2", "aln": "MDFQHRPGGKTGSGGVASSSESNRDRRERLRQLALETIDIN------------KDPYFMKNHLGSYECKLCLTLHNNEGSYLAHTQGKKHQTNLARRAAKEAKEAP-AQPAPEKVKVEVKKFVKIGR--------PGYKVTKQRDTEMGQQSLLFQIDYP-EIAEG---------VMPRHRFMSAYEQRIEPPDRRWQYLLMAAEPYETIAFKVPSREIDKAEGKFWTHWNRETKQFFLQFHFKMEKPPAPPSLPAGPPGVKRPPPPLMNGLPPRPPLPDALPPPPPGGLPLPPMPPTGPAPSGPPGPPQMPPPAPGVHPPAPVVHPPTSGVHPPAPGVHPPAPVVHPPTSGVHPPAP-------GVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPPAPAVHPQAPGVHPPAPGIHPQAPGVHPQPPPGVHPAAPGVHPQPP-------GVHP-TPMPPMLRPPLPSDGPGNMPPPPPGN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q15428-1", "uniprot_id": "SF3A2_HUMAN", "id": "Q15428-1", "name": "Splicing factor 3A subunit 2", "aln": "MDFQHRPGGKTGSGGVASSSESNRDRRERLRQLALETIDIN------------KDPYFMKNHLGSYECKLCLTLHNNEGSYLAHTQGKKHQTNLARRAAKEAKEAP-AQPAPEKVKVEVKKFVKIGR--------PGYKVTKQRDSEMGQQSLLFQIDYP-EIAEG---------IMPRHRFMSAYEQRIEPPDRRWQYLLMAAEPYETIAFKVPSREIDKAEGKFWTHWNRETKQFFLQFHFKMEKPPAPPSLPAGPPGVKRPPPPLMNGLPPRPPLPESLPPPPPGGLPLPPMPPTGPAPSGPPGPPQLPPPAPGVHPPAPVVHPPASGVHPPAPGVHPPAP---------------------GVHPPAPGVHPPTSGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPAAPAVHPQAPGVHPPAPGMHPQAPGVHPQPP-GVHPSAPGVHPQPPGVHPSNPGVHPPTPMPPMLRPPLPSEGPGNIPPPPPTN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VU15-1", "uniprot_id": "Q9VU15_DROME", "id": "Q9VU15-1", "name": "Splicing factor 3A subunit 2", "aln": "MDFQNRAGGKTGSGGVASWSETNRDRKERLRQLALETIDLN------------KDPYFMKNHLGSYECKLCLTLHNNEGSYLAHTQGKKHQDNLARRAAKEAKEAPSSLLAPEKPRVEPKKFVKIGR--------PGYRVTKQRELSNGQQSLLFQVDYP-EITES---------IVPRHRFMSAYEQKIEPPDRKWQYLLFAAEPYETIGFKVPSREVEKSEGKFWTHWNRDTKQFFLQFAFKFEPKILPP-----------PPPNLHRALGP------------PGGFPMP-------------------------GPPRPAMHPMFNGVHPPPPMLSNN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q07350-1", "uniprot_id": "PRP11_YEAST", "id": "Q07350-1", "name": "Pre-mRNA-splicing factor PRP11", "aln": "MNYLEGVGSKKGGGGIASESQFNLQRRKEVESLLSKGENVPYTFQDEKDDQVRSNPYIYKNHSGKLVCKLCNTMHMSWSSVERHLGGKKHGLNVLRRGISIEKSSLGREGQTTHDFRQQQKIIEAKQSLKNNGTIPVCKIATVKNPKNGSVGLAIQVNYSSEVKENSVDSDDKAKVPPLIRIVSGLELSDTK-QKGKKFLVIAYEPFENIAIELPPNEILFSENNDMDNNNDGVDELNKKCTFWDAIS------------------------------------------------------------------------KLYYVQFFFKQAEQEQADV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:: . *.*.*.**:** *: * :*::.:..* : :: .:**: *** *. **** *:* . .* * **** *: **. . *.: . : : :*::: : * :::. :: . *. .* :*::*. *: *. : * *::*. * :: ::*::* **:*.*.:::*..*: :*.: : : * :: . .. . : ", "identical_positions": 56, "similar_positions": 84, "identity": "10.83%" }, { "cls_id": "homologset.agr.RGD:1308628", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BZ20-1", "uniprot_id": "PAR12_MOUSE", "id": "Q8BZ20-1", "name": "Protein mono-ADP-ribosyltransferase PARP12", "aln": "MAQAAVAVAEVTQLLCAAGGALELAELRRRLRTS-LGTDALERLLRDCGRFVVASRAVVAVGAGREAAAAASERLVLAVSSLRLCRAHQGPKPGCTGLCAQLHLCKFLIYGNCKFLKTGKNCRNGHNLKTDHNLSVLRTHGVDHLTYTELCQLLLQNDPSLLPDICLHYNKGDGPFGSCSFQKQCIKLHICQYFLQGECKFGTSCKRSHEFTNSESLEQLERLGLSSDLVSRLLSTYRNAYDIKNKGSALSKVSPSPAGPQGSSERKDSSGPVSPGTPSQE---------ESEQICLYHIRKSCSFQEKCHRVHFHLPYRWQFLDGGKWKDLDNMELIEEAYSNPSKDRIVYTESAAGFHFDNLDFNSMKFGNTLARRLSTASSVTKPPHFILTTDWIWYWMDEFGSWQEYGRQGSGHPVTTISSSDVERAYLAFCAPGADAQAATLKFQAGKHNYELHFKAFLQKNLVYGTIRKVCRRPKYVSPQDVQMKQSCNTKLHGPKSIPDYWDPAALPDLGFKKITLSSSSEEYQKVWNIFNRTLPFYFVQKIERIQNMGLWEVYQWQKCQMQKQNGGKEVDERQLFHGTSANFVDAICQQNFDWRVCGLHGTSYGKGSYFARDAAYSHHYSKSDTHSHMMFLARVLVGDFVRGSTSFVRPPAKEGQSNAFYDSCVNSMSDPTIFVVFEKHQVYPEYLIQYSTSS---KPPASPSIFVALG-------------NLFTSRQ-----------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A3V3-1", "uniprot_id": "D4A3V3_RAT", "id": "D4A3V3-1", "name": "Protein mono-ADP-ribosyltransferase PARP12", "aln": "MAQAAVAVAEVTQLLCAAGGALELAELRRRLRTS-LGADALERLLRDRGRFVVASREGTGPAT---AAAAASERVVVAVSSLRLCRAHQGPKQGCTGLCAQLHLCKFLIYGNCKFLRTGKNCRNGHNLKTDHNLSVLRTHGIDHLTYTELCQLLLQNDPSLLPDICLHYNKGDGHFGSCSFQKQCIKLHICQYFLQGECKFGTSCKRSHEFTNSENLEKLEKLGLSSDLVSRLLSTYRNAYDIKNKGSALSKVSSSPAGPQGTSERKDSS--VSPGTLSQE---------ESEQICLYHIRKSCSFQDKCHRVHFHLPYRWQFLDGGEWKDLDNMELIENAYCNPSKDRIVYTESAAGFHFDNLDFNSMKLGHTLARRLSTASSVTKPPHFILTTEWAWYWMDEFGSWQEYGRQGTGHPVTTISSSDVEKAYLSFCVPGADAQAAILKFQAGKHNYELDFKAFLQKNLVYGTVRKVCRRPKYVSPQDVQMKQSCNTKLHGTKSIPDYWDPAALPDLGFKRITLSSSSEEYQKVWNLFNRTLPFYFVQKIERIQNLGLWEVYQWQKGQMQKQNGGKEVDERQLFHGTSTNFVDAICQQNFDWRVCGLHGTSYGKGSYFARDAAYSHHYSKSDTHSHTMFLARVLVGDFVRGSTSFVRPPAKEGQSNAFYDSCVNSMSDPTIFVVFEKHQVYPEYLIQYSTSS---KPPAGPSIFVALG-------------NLFTSRQ-----------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H0J9-1", "uniprot_id": "PAR12_HUMAN", "id": "Q9H0J9-1", "name": "Protein mono-ADP-ribosyltransferase PARP12", "aln": "MAQAG-VVGEVTQVLCAAGGALELPELRRRLRMG-LSADALERLLRQRGRFVVAVRAG--------GAAAAPERVVLAASPLRLCRAHQGSKPGCVGLCAQLHLCRFMVYGACKFLRAGKNCRNSHSLTTEHNLSVLRTHGVDHLSYNELCQLLFQNDPWLLPEICQHYNKGDGPHGSCAFQKQCIKLHICQYFLQGECKFGTSCKRSHDFSNSENLEKLEKLGMSSDLVSRLPTIYRNAHDIKNKSSAPSRVPP-LFVPQGTSERKDSSGSVSPNTLSQE---------EGDQICLYHIRKSCSFQDKCHRVHFHLPYRWQFLDRGKWEDLDNMELIEEAYCNPKIERILCSESASTFHSHCLNFNAMTYGATQARRLSTASSVTKPPHFILTTDWIWYWSDEFGSWQEYGRQGTVHPVTTVSSSDVEKAYLAYCTPGSDGQAATLKFQAGKHNYELDFKAFVQKNLVYGTTKKVCRRPKYVSPQDVTTMQTCNTKFPGPKSIPDYWDSSALPDPGFQKITLSSSSEEYQKVWNLFNRTLPFYFVQKIERVQNLALWEVYQWQKGQMQKQNGGKAVDERQLFHGTSAIFVDAICQQNFDWRVCGVHGTSYGKGSYFARDAAYSHHYSKSDTQTHTMFLARVLVGEFVRGNASFVRPPAKEGWSNAFYDSCVNSVSDPSIFVIFEKHQVYPEYVIQYTTSS---KPSVTPSILLALG-------------SLFSSRQ-----------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P914-1", "uniprot_id": "A0A8M1P914_DANRE", "id": "A0A8M1P914-1", "name": "", "aln": "MTEAA-----IIKNICANNGSIAYADLLSALGMYDEAQDVLDVLISRSENCTVG--------------FFSGQKRVIVRTKVRLCRIQNCP------ACDNLHLCKGFLFGFCRFDRGRRGCRFSHDLDSAHNLMVLMANGLNTLDLKELRVLLLQSDNTLLPAVCHSYNNGVGEYGRCPDAEACKRLHICERYLQGHC----DCTRAHDFYEPHPLKTLQDRGVPTELMALMKDLYSNIEALRRTNRNKPNTAPNNRRGPNVNNRRSSSVEFTAANRETEAPATQHTYTEKSEICMYFIKGHCKHGGTCRREHSILPYKWEVKEGSVWKALPDNEAIEKDYCDPTN-----IYSSGRFP---VCFDTMTQGCVAVRRLSTVSSVLQP-SFILTTEWLWFWEDEFGNWIQYASADGGHKISSITSAELEQKYQA-------DQSAVLEFSAGSQTYTLSFQDMIQTNKQYKTKKVIRRRPKFVSAADVKTIKSTKRAPISFKTLPEHWDKALTPETGCKRVQLTKTTAEFIKIQELFNRTMRGFTIQNIERIQNKALWEVFQWQKDCMKKNSRGRDVSEKQLFHGTDSKFVDTICLNNFDWRICGVNGTAYGKGSYFARDAKYSHSYTN-NSGTRSMFVCRILVGDYTKGDSSYLRPPSKDGGDTVFYDSCVNDVCDPSIFVVFEKHQIYPEYLIQYRDSSEWASPAVRPAVTTTRAVPASIRTTPSYNSSHFTSSNTSSSVKSSHVASSNTSSWVNSSPFNSSPNTASSYNSTSFAYSNSASTTNSSPFNSSPNTSSYVHLSRSASVYSPPPRKPAKAENSCVIS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*::*. : : :** .*:: .:* * . *.*: *: . .*. : :: *:. : :**** :: . * :****: :::* *:* : :.** .*.* : *** ** ::*:: * .** **:*.* *** :* **:* * .* *. : * :****: :***.* .*.*:*:* :.. *: *: *:.::*:: : * * ::... ..... . .:*:.** .:. . . * * .:**:*.*: *.. .*:* * ***:*:. : . *: * : * **: *.:*. *:. * : *::*. * . .*****.*** :* *****:* *:* ****.* :*. . * :::::*:::*: * : *:* *:*.**.:.* * *: ::*.* * * : : ****:**. ** :: : . *::*::** : *: * ::: *:.:: *: *: ::****: : :*:***:** .****:**** *:*:. *: *.*:******.: ***:** :*****:**::**:*********** *** *:: :: :: **:.*:***::.:*.:*::***:*:* ...*******.:.**:***:*****:****:*** ** .*.. *:: : . . *:* : ", "identical_positions": 257, "similar_positions": 233, "identity": "31.11%" }, { "cls_id": "homologset.agr.RGD:1308629", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JG52-1", "uniprot_id": "A0A0G2JG52_MOUSE", "id": "A0A0G2JG52-1", "name": "", "aln": "MPLSPPSQGDPREASPSKAPKKHPTFHIWRSKKKQSPSS-SCGVFIPHP-PGAFGETRAFLVPDGS--QGEPQELTLHGGELQLSDTPSEVPGPSSTESAMLKKSRAQPPEDTRRKPVLEKLGTLFTAGRRRNTRNGLESPTNSNSK-------SASAKVPKTGSEKTKAQDNQLKATDAGEA------GPRQEAEGQPVESCVQATPCDAEQSP--CSSINVGVVQQCHSNDSAQLEPLQAEGETFPDATTAAKELLHSSPGNRSRQESAETPARSPGEEALPGAGLQPETARGVS---GSPPEEHLVGGVGEAPDGAPGVGAEAGSLGA--------PGDAVPPGEPPAQDAETSR-------TAGSVDRAHPTKVLTLDIYLSKTEVAQVDEPASIAPGTDD-CEDSDDMEKRSSGRRSGRRRKSQKSTDSPGADAVAPESAAKDEAVFDDEVAPDAAAENCLAERKVKSVQAVPDGGAAPVACPEPKASSCPRGQPRGEPDRSK----PLSPTKRKGRSRVPEAVPSSPGSGSRAPAKESPPKRAP--------AAADSGEEAGRVVPRELTVKSSSLLPEIKPEHKRGPLPHHF-DSRGDGGRSR-------GTGASDADGLKPRNQFGVGRSTVTTKVTLPARPKHVELNLKTPKNPDSLGNEHNSFSQPVHKGNTANKISLFENKRANSSPRHPDVRNTRNNPPSSKTFVGRAKLNLAKKAKEMEQPEKKAVSTSHQNGLVVKEPSAEGKGTAVPVPREEIRPATRGGEGESTKDQVLRPEPEQSDKLDVQTDTAYPSHPGPTALVPVKDSELSGEGQPEAADSKGP--VLNNTSDVAQDIAAICDAREAP----PKPQDAFSDSQPASAAESARESSLPPSAPISVDAPQDGCVQVPICSVPCTALEVSENHNGCVSPVS-PHTEKTPISKPGVGEASPPSTPEHSPETMGKDCPSKVLVQVRSFVLPVENPQDVSSQVISESSEVREAQLPSCHSNEPEVVSVTTCVPQHEDAPDTSPKDIHHREGHVAQSRPHITQSGPEKAPPIQS---SSGMPQTAEFILTHSPSSRSHAEGPQRPGQDATS-PLTPTRLLNISAGSDNSVLDSSSDMEKFTEIIKKMDSAVCVPQKKKKARVPNSPAPHFAMPPIHEDSLEKVFDPNVFTIGLGKKKESLAEVSPALHLLQNHDPISKLRAKRASTEQSIVFKSLHTNSNGKSEPQTTSEASDKENRDINSGGVKRSRLENSTLFSSMLSSLPQDKVFSPSVTSVNTMSTSFSTSQNSSVSQSSVVQPRKEGGLPCGSDKEQPHLAPHNSLKVFNFNSSNTSRLGS---SHMEKYPQKEGSKEDVNSQGNLQLPENNLSDLPKLKN-----SDGVEGILKSNLPNVGSVDADFLGLFKASRYDPGHSFSGMSLSDSMTLRGSMHSKLNPRPGKVVIFSEPDVSEECIEVFGDIQDCSSWRLSPVIVVKVVRGCWILYEKANFEGHSLALEEGELELSSIWGTEEMLD--EEAESDKPVVIGSIRHVVQDYRISQIDLFTEPEGLGLLNSYFDDTEEMQGFPVMQKTCSIKVHWGTWLIYEEPGFQGVPFILEPGEYPDLSFWDTEEAYIGSMRPLKMGGRKVEFPTDPKVVIYEKPSFEGRCMELETEMSSFIMEGGETEETTG---NNNLPFTSVGSMKVLRGVWVAYEKCGFTGHQYLLEEGEYRDWNAWGGYNGELQSLRPILSDFSNAHMIMYSEKNFGSKGSSIDVLGIVANLKETGYGVKTQSINVLSGVWVAYENPDFTGEQYVLDKGFYTSFEDWGGKNCKISSVQPICLDSFTGPRRRNQIHLFSEPQFQGQSQSFEETIDQIDDSFQTKSCRVLGGSWVAYDGENFSGNQYVLEEGHYPCLSAMGCLPGATLKSLRFIDFEFSEPTIILFERENFKGKKIELNAETVNLRSLGFNTQIRSVRVVGGIWVTYEYGNYRGRQFLLSPAEVPNWYEFSACRQIGSLRPFAQKRIYFRLRNKATGLFMSTNGNLEDLKLLRVQVMEDVGADDQIWIYQEGCIKCRIAEDCCLTIVGSLVTSGSKLGLALDQNVDSQFWCMKSDGRIYSKMKPNLVLDVKGGAQYDQNHIILNTVSTEKLTQVWEAMVL--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZD79-1", "uniprot_id": "D3ZD79_RAT", "id": "D3ZD79-1", "name": "", "aln": "MPLSPPSQGDSREASPSKPPKKHPTFHLWRSKKKQSPSS-SCGVFIPHP-PGALGEIRAFIVHDGN--PGEPQELTLHGGEPQLSDTPSEVPGPSSTESAMLKKSRAQPPEDTRRKPVLGKLGTLFTAGRRRNTRNGLESPTNSNSK-------SASAKVPETESEKSKAQGNQLKPTDAGEAGEAGEAGSRQEAEGQSAESSVQATPCDAGPSP--CSSIKVGVVQQCLCNDSAQLEPLQAEGETFPDATTAAKELLHSSPGNRSGQESAETPARSPGEDALPGAGLQREAARGVS---GSPPEEHLVGGVGEAPDGAPGVGSEAGSLGD--------PGDAVPPGEPPAQGAETSG-------TAGPADRAHPTKVLKLDIYLSKTEVAQVAEPASIAPGTDDCCEDSDDMEKRSSGRRSGRRRKSQKSTDSPGADAVAPESAAKDDAVFDDEVAPDAAAENCTAERKVKSVQAVPDGGSASVASPEPKPSACPRGQPRAEPDRAK----PQSPTKRKGRSRVPEAVPSSPGSGSRAPAKESPPKRAP--------AAADGGEEAGRVVPRELTVKSSSLLPEIKPEHKRGPLPHHFGDSRADAGRSRES---SRGTGASDADGLKPRNQFGVGRSTVTTKVTLPARPKHVELNLKTPKNPDGLGNEHNPFSQPVHKGNTANKISLFENKRASSSPRHPDVRNTRNNPPSNKTFVGRAKLNLAKKAKEMEQPEKKAMSTSLQNGQVTKGPSAEGKNTDVPIAGEEILPATP------AKDQVLCPEPDQSDKLDVQTGTACPPQPAPPALVPEKDPELPREGHPEAADSQSPVLVLNNTNDPAQNITALHDARESP----PKPQGTFSDSQPAS--ESSRESPLPPSAPMPVDAPQDGCVQVPMCNVPYTALEVSENHDGCAVPVS-PHAEKTPVTKPGGREASPPSTPEHCPETMGKECPSKVLVQVRSFVLPVENPQDVSSHVIAESSEVREVQLPSCHSNEPEVVSVTACGPQHEDTPDTSPKDTHHAEERVSQSRPHIAQPEPEKDLPIEAQSESTGTPLTVGFSPSHSPSSRSHPEGLQRPGPSMTS-PLTPAGLLNVSASSDDSVLDSSSDMEKFTEIIKKMDSAVCVPQKKKKSRVPNSPTPHFAMPPIHEDSLEKVFDPNVFTIGLGKKKENQPEVSPALQLLQNHDPISKLRAKRASTEQSIVFKSLHANGNGKGEPQTTSEANDKENRDINSGGVKRSRLEKSTLFSSMLSSLPQDKVFSPSVTSVHTMSTSFSTSRNSSVSQSSVVQPRKEGDLPCGSDKEQSQLAPHDSLKVFNFNSSSTSHLGLRSPGHMEKCPPKEESKEGVSSRGSLPLPENSLSDLTKLKN-----SDAVESVLKSNLPNVGSVDTDFLGLFKASRYDPGLSFSAMSLSDSMTLRGSMHNKLNPRPGKVVIFSEPDVSEECIEVFGDIQDCSSWSLSPVVLVKVVRGCWILYEKANFEGHSLALEEGELELSNLWGTEDILD--EEAESDKPVVIGSIRHVVQDYRISQIDLFTEPDGLGLLNSYFDDTEEMQGFGVMQKTCSIKVHWGTWLIYEEPGFQGIPYILEQGEYPDLSFWDTEEAYIGSMRPLKMGGRKVEFPTDPKVVIYEKPSFQGRCMELETEMCGLVTEGGETEETTGKETNGNVPFTSVGSMKVLRGVWVAYEKCGFTGHQYLLEEGEYRDWNAWGGYSAELQSLRPILSDFSNAHMIMYSEKNFGSKGSSIDVLGIVANLKETGYGVKTQSINVLSGVWVAYENPDFTGEQYVLDKGFYTSFEDWGGKNCKISSVQPICLDSFTGPRRRNQICLFSEPQFQGQSQSFEETAGQIGDSFQTKSCRVLGGSWVAYDGENFSGNQYVLEEGHYPCLSAMGCLPGATLKSLRFIDFEFSEPTIILFERENFKGKKIELNAETVNLRSLGFNPQIRSVRVVGGIWVTYEYGNYRGRQFLLSPAEVPNWYEFSACRQIGSLRPFAQKRIYFRLRNKATGLFMSTNGNLEDLKLLRVQVMEDVGADDQIWIYQDGCIKCRIAEDCCLTIVGSLVTSGSKLGLALDQNVDSQFWCMKSDGRIYSKLKPNLVLDVKGGAQYDQNHIILNTVNTEKLTQVWEAMVL--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y4K1-3", "uniprot_id": "CRBG1_HUMAN", "id": "Q9Y4K1-3", "name": "Beta/gamma crystallin domain-containing protein 1", "aln": "MPLSPPAQGDPGEPSPCRPPKKHTTFHLWRSKKKQQPAPPDCGVFVPHPLPAPAGEARALDVVDGKYVVRDSQEFPLHCGESQFFHTTSEALGSLLLESGIFKKSRAQPPEDNRRKPVLGKLGTLFTAGRRRNSRNGLESPTRSNAKPLSPKDVVASPKLPERESERSRSQSSQLKQTDTSEEGSP--RENPREAEGELPESGGPAAPPDAELSPRWSSSAAAVAVQQCHENDSPQLEPLEAEGEPFPDATTTAKQ-LHSSPGNSSRQENAETPARSPGEDASPGAGHEQEAFLGVRGAPGSPTQERPAGGLGEAPNGAPSVCAEEGSLGPRNARSQPPKGASDLPGEPPAEGAAHTASSAQADCTARPKGHAHPAKVLTLDIYLSKTEGAQVDEPVVITPRAED-CGDWDDMEKRSSGRRSGRRRGSQKSTDSPGADAELPESAARDDAVFDDEVAPNAASDNASAEKKVKSPRAALDGGVASAASPESKPSPGTKGQLRGESDRSKQPPPASSPTKRKGRSRALEAVPAPPASGPRAPAKESPPKRVPDPSPVTKGTAAESGEEAARAIPRELPVKSSSLLPEIKPEHKRGPLPNHF-NGRAEGGRSRELGRAAGAPGASDADGLKPRNHFGVGRSTVTTKVTLPAKPKHVELNLKTPKNLDSLGNEHNPFSQPVHKGNTATKISLFENKRTNSSPRHTDIRGQRNTPASSKTFVGRAKLNLAKKAKEMEQPEKKVMPNSPQNGVLVKETAIETK---VTVSEEEILPATRGMNGDSSENQALGPQPNQDDKADVQTDAGCLSEPVASALIPVKDHKLLEKEDSEAADSKSL--VLENVTDTAQDIPTTVDTKDLPPTAMPKPQHTFSDSQSPA--ESSPGPSLSLSAPAPGDVPKDTCVQSPISSFPCTDLKVSENHKGCVLPVSRQNNEKMPLLELG-GETTPPLSTERSPEAVGSECPSRVLVQVRSFVLPVESTQDVSSQVIPESSEVREVQLPTCHSNEPEVVSVASCAPPQEEVLGN--EHSHCTAELAAKSGPQVIPPASEKTLPIQAQSQGSRTPLMAESSPTNSPSSGNHLATPQRPDQTVTNGQDSPASLLNISAGSDDSVFDSSSDMEKFTEIIKQMDSAVCMPMKRKKARMPNSPAPHFAMPPIHEDHLEKVFDPKVFTFGLGKKKESQPEMSPALHLMQNLDTKSKLRPKRASAEQSVLFKSLHTNTNGNSEPLVMPEINDKENRDVTNGGIKRSRLEKSALFSSLLSSLPQDKIFSPSVTSVNTMTTAFSTSQNGSLSQSSVSQPTTEGAPPCGLNKEQSNLLPDNSLKVFNFNSSSTSHSSLKSPSHMEKYPQKEKTKEDLDSRSNLHLPETKFSELSKLKNDDMEKANHIESVIKSNLPNCANSDTDFMGLFKSSRYDPSISFSGMSLSDTMTLRGSVQNKLNPRPGKVVIYSEPDVSEKCIEVFSDIQDCSSWSLSPVILIKVVRGCWILYEQPNFEGHSIPLEEGELELSGLWGIEDILERHEEAESDKPVVIGSIRHVVQDYRVSHIDLFTEPEGLGILSSYFDDTEEMQGFGVMQKTCSMKVHWGTWLIYEEPGFQGVPFILEPGEYPDLSFWDTEEAYIGSMRPLKMGGRKVEFPTDPKVVVYEKPFFEGKCVELETGMCSFVMEGGETEEATG---DDHLPFTSVGSMKVLRGIWVAYEKPGFTGHQYLLEEGEYRDWKAWGGYNGELQSLRPILGDFSNAHMIMYSEKNFGSKGSSIDVLGIVANLKETGYGVKTQSINVLSGVWVAYENPDFTGEQYILDKGFYTSFEDWGGKNCKISSVQPICLDSFTGPRRRNQIHLFSEPQFQGHSQSFEETTSQIDDSFSTKSCRVSGGSWVVYDGENFTGNQYVLEEGHYPCLSAMGCPPGATFKSLRFIDVEFSEPTIILFEREDFKGKKIELNAETVNLRSLGFNTQIRSVQVIGGIWVTYEYGSYRGRQFLLSPAEVPNWYEFSGCRQIGSLRPFVQKRIYFRLRNKATGLFMSTNGNLEDLKLLRIQVMEDVGADDQIWIYQEGCIKCRIAEDCCLTIVGSLVTSGSKLGLALDQNADSQFWSLKSDGRIYSKLKPNLVLDIKGGTQYDQNHIILNTVSKEKFTQVWEAMVLYT", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******:***. *.**.:.****.***:*******.*:. .****:*** *.. ** **: * **. :.**:.** ** *: .*.**. *. **.::**********.****** *************:********.**:* **.*:*: **::::*..*** **:.* :****: ** *:* ** ** .** . .**** ***.*****:****.******:**: ******* * **.**********:* **** : *: ** ***.:*: .**:****:***.* :* **** * : ******:.* : ** . .:***:***.********* *** **. *:* ::* * * **************** ************ *****:*:*********:**::*. **:**** :*. *** *..*.**.*.*. .:** *.*.**:* . **********. ****:.*.**.***********.* :**:.****.*.:****.********************:** :.*.:.**** ..************:****************:************* *.******.***********.*********:.*****.*:*. **.*.*.************************.:..* *** :.* .: * * *.:. *** *** :::*.* *:*:*.** ****.:. ..* ..**:* ** :* : ..*****:. **:*..* **:*.: *::: * **** :*****..: **: ..*. *** . *.*:* *** *:...* * *:*****.**. *** : ** *: : * *::** :.*:.**::*.:***:*************..*****:**.*******.***:***********::* * :*:. .. :. * .::* *:: . .** **:: .: * . ::**** .* ***. *. :*: ***:**.**:**:**************:******:* *:**:*:****:*********** *******:***:*******. .*:****:*:** *. ****.****:***::*****:* **:.** . .* .******:..**:******:*:****:********:********:**:*:****:*.*:***** ** .** *** :***.:* *.:**********.**: . .**** * ** :**.:.*:..* ***..:*:*.**** :: :*.::****** .. *:**:****:*****. ***.*****:******::.***********:*******:*****.******** ****:::***********:.******:.*********.:** *::*: **********************:*:*******:***:*.************ *******:*****************:*:*** **************************************:**** *:*:*:**** *..:: *******:** :.::*************:****** *****************:*****..*********.***************************************************************:*************************************** *********:******* .**.***.****** *****.******:******************* ****:*******.*************:*********************.*****:*:**********.********************.**********.******************************:****************:*********************************.*****.:*********:*******:***:************..**:********* ", "identical_positions": 1471, "similar_positions": 391, "identity": "68.45%" }, { "cls_id": "homologset.agr.RGD:1308631", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4A930-1", "uniprot_id": "D4A930_RAT", "id": "D4A930-1", "name": "", "aln": "MVLPTCPMAEFALPRHSAVMERLRRRIELCRRHHSTCEARYEAVSPERLELERQHTFALHQRCIQAKAKRAGKHRQPPAAATAPAAAPAPAPAPAAARLDSADGPEHGRPVAHLHDPVKRSLDSAASPQNGDQPNGYGDLFPGHKKTRREAPLGVSVSANGLPPASPLGQPDKPPVGDALQTGGKHSLGLDPINKKCLADSSIHLNGGSNSSEPFPLSLSKELKQEPVDDLPCMIAGAGSSVAQSNLMPDLNLNEQEWKELIEELNRSVPDEDMKDLFTEDFEEKKDPEPPGSATQTPLAQDINIKTEFSPAAFEQEQLGSPQVRAGSAGQTFLAPSSAPVGTDSPSLGNSQTLFHTTGQPGVDSSSPNLMPASAQAQNAPRALTSVVLPSQGPGGASELSSAHQLQQIAAKQKREQMLQNPQQTAPAPGPGQLSTWQQAGPSHSPLDAPYPMEKPASPSGYKQDFTNSKLLMMPSVNKSSPRPGGPYLQPSHSNLLSHQSPSNLNPNPVNNQGSMLDYGNTKPLSHYKADCGQGGPGSGQNKPALMAYLPQQLPHLSNEQNSLFLMKPKPGNMPFRSLVPPGQEQNPSSVPVPAPAASVGTQP-SVSVASTHSSS-YLSSQQQAAVMKQHQLLLDQQKQREQQ--QLQQQQFLQR-QHLLAEQEKQQFQRHLTRPPPQYQDPTQSTFQQQVGQFTGPSAAVPGMNNLGPSNSSCPRVFPQPGTLMSMGPGHAPVSSLPPSSGQQDRGVAQFTGSQSLPHNSLYGMASGLAQIVAQPPPQATSTHAHIPRQTNVGQNASTSAAYGQNSLGSASLSQQHSKGTLPPGLAKPQVPRVSAAMGSQNPSWQHQGMPNLSSQTPGNSSVSPFTAASSFHR-QQAHLKMSAQQFSQAMPTRPMAPLSSAAAAGPMLPSVSTQQRNSAPAPAPPQAASQQGLPGLSPSGPELGAFGQSPTSQMNSRPGLHCAQAYPVRTMGQELPFAYSGQPGSSGLSSVAGHTDLIDSLLKNRTSEEWINELDDLLGSQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6T264-1", "uniprot_id": "MAML1_MOUSE", "id": "Q6T264-1", "name": "Mastermind-like protein 1", "aln": "MVLPTCPMAEFALPRHSAVMERLRRRIELCRRHHSTCEARYEAVSPERLELERQHTFALHQRCIQAKAKRAGKHRQPPAAATAPVAAPAPASAPAAARLDAADGPEHGRPVAHLHDTVKRSLDSAASPQNGDQPNGYGDLFPGHKKTRREAPLGVSVSANGLPPASPLGQPDKPSGGDTLQTAGKHSLGLDPINKKCLADSGIHLNGGSNSSEPFPLSLSKELKQEPVDDLPCMIAGAGGSVAQSNLMPDLNLNEQEWKELIEELNRSVPDEDMKDLFTEDFEEKKDPEPPGSATQTPLAQDINIKTEFSPAAFEQEQLGSPQVRAGSAGQTFLGASSAPVGTDSPSLGSSQTLFHTTSQPGVDNSSPNLMPASAQAQSAQRALTSVVLPSQGPGGASELSSAHQLQQIAAKQKREQMLQNPQQAAPAPGPGQLATWQQAGPSHSPLDVPYPMEKPASPSGYKQDFTNSKLLMMPGVNKSSPRPGGPYLQPSHSNLLSHQSPSNLNQNPVNNQGSVLDYGNTKPLSHYKADCGQGGPGSGQNKPALMAYLPQQLPHLSNEQNSLFLMKPKSGNMPFRSLVPPGQEQNPSSVPVAAPAASVGTQP-TVSVASTHNSSPYLSSQQQAAVMKQHQLLLDQQKQREQQQQQLQQQQFLQR-QHLLAEQEKQQFQRHLTRPPPQYQDPTQSTFPQQVGQFTGPSAAVPGMNNLGPSNSSCPRVFPQPGTLMSMGPGHAPVSSLPSSSGQQDRGVAQFTGSQSLPQNSLYGMASGLAQIVAQPPPQATSTHAHIPRQTNVGQNASTSAAYGQNSLGSASLSQQHSKGTLPPGLTKPQVPRVSAAMGSQNASWQHQGMPNLSSQTSGNSSVNPFTAAPSFHI-QQAHLKLAGQQFSQAMPSRPMAPLSSAGAAGPMLPPVSAQQRNSAPASAPPQAAPQQGLPGLSPSGPELGAFGQSPTSQMSGRPGLHCAQAYPVRTMGQELPFAYSGQPGSSGLSSVAGHTDLIDSLLKNRTSEEWINELDDLLGSQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92585-1", "uniprot_id": "MAML1_HUMAN", "id": "Q92585-1", "name": "Mastermind-like protein 1", "aln": "MVLPTCPMAEFALPRHSAVMERLRRRIELCRRHHSTCEARYEAVSPERLELERQHTFALHQRCIQAKAKRAGKHRQPPAAT-------APAPAAPAPRLDAADGPEHGRPATHLHDTVKRNLDSATSPQNGDQQNGYGDLFPGHKKTRREAPLGVAISSNGLPPASPLGQSDKPSGADALQSSGKHSLGLDSLNKKRLADSSLHLNGGSNPSESFPLSLNKELKQEPVEDLPCMITGTVGSISQSNLMPDLNLNEQEWKELIEELNRSVPDEDMKDLFNEDFEEKKDPESSGSATQTPLAQDINIKTEFSPAAFEQEQLGSPQVRAGSAGQTFLGPSSAPVSTDSPSLGGSQTLFHTSGQPRADNPSPNLMPASAQAQNAQRALAGVVLPSQGPGGASELSSAHQLQQIAAKQKREQMLQNPQQATPAPAPGQMSTWQQTGPSHSSLDVPYPMEKPASPSSYKQDFTNSKLLMMPSVNKSSPRPGGPYLQPSHVNLLSHQPPSNLNQNSANNQGSVLDYGNTKPLSHYKADCGQGSPGSGQSKPALMAYLPQQLSHISHEQNSLFLMKPKPGNMPFRSLVPPGQEQNPSSVPVQAQATSVGTQPPAVSVASSHNSSPYLSSQQQAAVMKQHQLLLDQQKQREQQQKHLQQQQFLQRQQHLLAEQEKQQFQRHLTRPPPQYQDPTQGSFPQQVGQFTGSSAAVPGMNTLGPSNSSCPRVFPQAGNLMPMGPGHASVSSLPTNSGQQDRGVAQFPGSQNMPQSSLYGMASGITQIVAQPPPQATNGHAHIPRQTNVGQNTSVSAAYGQNSLGSSGLSQQHNKGTLNPGLTKPPVPRVSPAMGGQNSSWQHQGMPNLSGQTPGNSNVSPFTAASSFHMQQQAHLKMSSPQFSQAVPNRPMAPMSSAAAVGSLLPPVSAQQRTSAPAPAPPPTAPQQGLPGLSPAGPELGAFSQSPASQMGGRAGLHCTQAYPVRTAGQELPFAYSGQPGGSGLSSVAGHTDLIDSLLKNRTSEEWMSDLDDLLGSQ", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "********************************************************************************: ***.*..*.***:*********.:****.***.****:******* *********************::*:***********.***. .*:**:.********.:*** ****.:*******.**.*****.********:******:*: .*::***********************************.**********..*******************************************..*****.*******.*******:.** .*..************.* ***:.**************************************::***.***::****:*****.**.***********.**************.***************** ******.***** *..*****:*******************.*****.************.*:*:***********.********************** * *:****** :*****:*.** *************************** :********* ****************************.:* ********.********.**************.*.**.******.*****..***********.***.:*:.********::***********. *************:*.***********:.*****.**** ***:** *****.***.**.***********.**.***.*.*****.*** ******::. *****:*.*****:***.*.*.:**.**:***.****.*** :*.*********:*******.***:***..*.****:******* *************.*************************:.:********", "identical_positions": 860, "similar_positions": 132, "identity": "84.07%" }, { "cls_id": "homologset.agr.RGD:1308632", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K3P2-1", "uniprot_id": "A0A0G2K3P2_RAT", "id": "A0A0G2K3P2-1", "name": "", "aln": "MNTKDFVVIPWGKPGSSVKLKYKGVQELQMEKIQLELENQQMEKKLREFQSTWDKGKEGVMASGYHWKSGNVSKLRNPSGRMSQSKASATKLSAGKVKLKLLKEEIQAPAKQQVSYKMAHSTGSENPKTKRKVCGQCENKAALLVCLECGEDYCSGCFARMHQKGALKFHRTTLLQPKCQIISNVLDAAHQFIKEVNP--PNEGKNPTEASSKSQQKPK-ALLLQKSSEVETTATEGGKDGNPRYKTMWEMPFDEEASAQSFREALTQWRAGHQEDNKEEDVHAKKPVFIFVESVEECEVQTNLKIWAEPINIEFTEDSLSYMEKLWLKKYRRTPLEQLHTMLPNTFPHPREAIAEALCTQKENDSDSDVEEIKVKYPPLFMPAEKLKVERPPPSLTIVELDSTHGAEFEDPGVAVPYRVELADSESQLSSTFPDYQT-CLPGENDIHHHLIFNKGKADLLSMCLRTNSGHHKDELK----------------------------------------------------------------------EEISSQDINTSLECSKQNERSNFEDSKTTKPP-LLRKVALRRKPVNERYQGPKKFFPADKNERLNALPSSSIKGSHSCSEITSTVSEDKLWVPVSSLSGCAGNTDVLKDQQSDENPLPHVQQQKTGQKSQRPSTANIPVSNSDQKDTSCLLSSYSRSKSADPQFPSRAASEISEIEYIDVTEQNELFGGNTVDQQALDTLEKELNILRNPADPSEESHSIPSEQFQAFNDNFLTLSRMSKDLLEMPCESEPSGTES-STPGRNSEMQPLLSLGDCSTDEEEEDFLDKQNVITLPWAKRA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q0P5X5-1", "uniprot_id": "ZBBX_MOUSE", "id": "Q0P5X5-1", "name": "Zinc finger B-box domain-containing protein 1", "aln": "---------------------------------------------------------------------------------------------------------------------MAHSTGSENPKTKRKVCGQCENKAALLVCLECGEDYCSGCFAKMHQKGALKFHRTTLLQPKSQILSNILIAAHQFIKEENP--PNEGNHPAEASSKSQQKPK-ALLQ-NSSEVGATASEGGEGENPRCKVMWEMPFDEEASAQSFREALTQWRAGHQEENKEEEVHAKKPVFIFLDSVEECEVQTNLKMWTEPINIEFTEDSLSYMETLWLKKYRRTPQEQLRTMLPNTFTHPHQATAEAQCTQNENESDSDVEEIKIKSPPLFMPVEKLNIERPPPSLTIVELDDTHGAEFEDPGIAVPYRVELADSESQLSSTFTDYQT-CFPCENEIHHHLIFNKGKADLLSLCLRTNSRYHKDDIKDFG------NTVESCTYSDEFKKIGETTSFEKNETEKNIDPQNNKDSVDSCMSLGSKGSLPTIDSSTSFIEENSSQDTNTSLKCSNQNERSNLGNSKTAKEP-LFQKVTIRKKLIKERYQGPKKFYSVDKNERLDVFPSSSIKGSHSCSEITSTVSEDKMWIPLSSLSGYAGSADALCDQQSDENPLPNMQQQKSGQKSQRPSTANIPISNPDQKDTSCLLFSYTRSKSAAAQMPSRAASEISEIEYIDVTDQSELFGGNTADRQALDTLEKELNILRKPADPSEDPHSLPSEELQAFNDNFLTLSQMSKDLLEMSRESDPHGAES-SSSGRNPEIQPLLSLGDYSTDEEEDEFLDKQHVIKLPWEKRA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A8MT70-1", "uniprot_id": "ZBBX_HUMAN", "id": "A8MT70-1", "name": "Zinc finger B-box domain-containing protein 1", "aln": "MNRKDFVVLPWGKPGNSVKLKYRNAQELRMEKVQLEFENQEMEKKLQEFRSTRNKEKEDRESSEYYWKSGKVGKLVNQSYMMSQNKGNVVKFSAGKVKLKLLKEQIQEPVKPTVNYKMANSSECEKPKINGKVCGQCENKAALLVCLECGEDYCSGCFAKVHQKGALKLHRTTLLQAKSQILFNVLDVAHQFIKDVNPDEPKEENNSTKETSKIQHKPKSVLLQRSSSEVEITTMKRAQRTKPRKSLLCEGSFDEEASAQSFQEVLSQWRTGNHDDNKKQNLHAA-----VKDSLEECEVQTNLKIWREPLNIELKEDILSYMEKLWLKKHRRTPQEQLFKMLPDTFPHPHETTGDAQCSQNENDEDSDGEETKVQHTALLLPVETLNIERPEPSLKIVELDDTYEEEFEEAENIVPYKVKLADADSQRSCAFHDCQKNSFPYENGIHQHHVFDKGKRDFLNLCLRNSSTYYKDNSKAETSNTDFDNIVDPDVYSSDIEKIEESTSFERNLKEKNIGLESNQKSDDSCVSLESKDTLLGRDLEKAPIEEKLSQDIKESLELSNLYKRPSFEESKTTKSSLLLQEIACRSKPITKQYQGLERFFIFDTNERLNLLPSHRLECNNSSTRIT-----------------------------------------LAGQKSQRPSTANFPLSNSVKESSSCLSSSHPRSRSAAAQSSSRAASEISEIEYIDITDQNELSLDDTTDQHTLDNLEKELQVLRSLADTSEKLYSLTSEEFPDFSSQSLNISQISTDFLKTSHVRGPCGVEELSCSGRDTKIQSLLSLSESSTDEEEEDFLNKQHVITLPWSKST", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **:*: .*:** : ****************************::*******:*******.*.**: *:* .******: ** *:* ::.:: :** *:*** .** .**** *: : .: :** . : * .**********:*.*:***:*::::**::::** . :*:**********:* **:***:.** *****.*****:**** *** .***:**.**::: .:* *:*:**:.*** ** *:: ..*::*.*.*::*** ***.*****.*: ***:. ***:*:***::** *.:* * *. .:* ** **:* :*:*** *:*.:***..* ::**: * ** *** : **: *: :*..: :***:* . *::::: * * :.::*** ::*: *.****: :** :: .:*.:.** :***********:*:**. ::.:*** *:.**:** .* .**************:*:*.** .:*.*:::**.*****::**. **.**. :*:.**:: *..: *.:*::*.*:*: . * *.*. * .**:.::*.****.: ******::**:**:**.*** * :", "identical_positions": 326, "similar_positions": 192, "identity": "38.53%" }, { "cls_id": "homologset.agr.RGD:1308633", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JT75-1", "uniprot_id": "A0A0G2JT75_RAT", "id": "A0A0G2JT75-1", "name": "", "aln": "-----MNHLPEDMENTLTGSQSSHASLRDIHSINPGQLMARIES--YEGREKKG-ISDVRRTFCLFVTFDLLFVTLLWIIELNVNG-GIENTLKKEVAHYDYYSSYFDIFLLAVFRFKVLILGYAVCRLRHWWAIALTTAVTSAFLLAKVILSKLFS--QGAFGYVLPIISFILAWIETWFLDFKVLPQEAEEENRLLLVQDASERAALIPAGLSDGQ--------FYSPPESEAGSEEEAEEKQDSEKPLLEL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DCI3-1", "uniprot_id": "STR3N_MOUSE", "id": "Q9DCI3-1", "name": "STARD3 N-terminal-like protein", "aln": "-----MNHLPEHMENTLTGSQSSHASLRDIHSINPAQLMARIES--YEGREKKG-ISDVRRTFCLFVTFDLLFVTLLWIIELNVNG-GIENTLKKEVIHYDYYSSYFDIFLLAVFRFKVLILGYAVCRLRHWWAIALTTAVTSAFLLAKVILSKLFS--QGAFGYVLPIISFILAWIETWFLDFKVLPQEAEEENRLLLVQDASERAALIPAGLSDGQ--------FYSPPESEAGSEEEAEEKQESEKPLLEL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95772-1", "uniprot_id": "STR3N_HUMAN", "id": "O95772-1", "name": "STARD3 N-terminal-like protein", "aln": "-----MNHLPEDMENALTGSQSSHASLRNIHSINPTQLMARIES--YEGREKKG-ISDVRRTFCLFVTFDLLFVTLLWIIELNVNG-GIENTLEKEVMQYDYYSSYFDIFLLAVFRFKVLILAYAVCRLRHWWAIALTTAVTSAFLLAKVILSKLFS--QGAFGYVLPIISFILAWIETWFLDFKVLPQEAEEENRLLIVQDASERAALIPGGLSDGQ--------FYSPPESEAGSEE-AEEKQDSEKPLLEL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W145-1", "uniprot_id": "STRT1_DROME", "id": "Q9W145-1", "name": "Steroidogenic acute regulatory protein-like", "aln": "MSNMDPSDVRSTAQLILANARQGNSAYNMQYDMSRAHSINLITEDFLAGYMQDGRMSVVRRFFCLFVTFDLVFVSLLWLICIVINGDNIFTAFHKQIVEYTIYKSLFDVVAVAICRFLVLIFFYAILYINHWSIIALSTSGSCLFLISKVFVFDWLDSKQQVFEVILIITSFILAWGEAWFLDCRVIPQERHAQHYFRTMTSNDRTPMEQPAILIEQERPPQSVTDFYSLMDTARHSDEEDELDDEYTQMGLDCLRKAYEIIESSDWKVEKVNQKGDTIHSTQRDKIGKIYKLTARIKYPAKALMEDLFYRIEDCPKWNPALLESKIVRKINSYTDITYQVSVGGGGGMVKSRDFVNLRSCRLFYNGQICDDDETAQLSSDDGNSSLNRSCEGSVSTISDGDSNTPLLPSSVSSCKATFPTSSKGAAMPFDTLGNSLGAKSLGPIVNFDEEPPPLDQDEFEDAKDKVDGEANNMTKPNVPSVGKTKDRVWVTSAVSVQYAAVPPSPKYTRGQNIVSGFAFREIVGKSDSCIVEWVLCLDLKGYIPRYVLDAALTSSMTDYISNLRKHVNELRQKGRGRAPRTH", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..: . : *:.::..::: . :.:. : : * . * :.* :* *** *********:**:***:* : :** .* .::.*:: .* *.* **:. :*: ** ***: **: :.** ***:*: :. **::**:: . :. * .* :* * ****** *:**** :*:*** . :: : : . .. . *. * : : *** :: *:* * .:: : *: ", "identical_positions": 78, "similar_positions": 83, "identity": "13.38%" }, { "cls_id": "homologset.agr.RGD:1308634", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZFK9-1", "uniprot_id": "D3ZFK9_RAT", "id": "D3ZFK9-1", "name": "Protein amnionless", "aln": "MGALGR-VLLWLQLCALTRAAYKLWVPNTSFDTASNWNQNRTPCAGDAVQFPADKMVSVLVRDSHAISDMLLPLNGEFVLASGAAFSAAGGDSDPACNPGAPLLFRNPDRFSWLDPHLWSSGT------QESGIFFVDAERVPCTYDDVLFPRNGSFRVALGPGPNPVHVRSVSAVGQTFTRDEDLAAFLASREGRLRFHGSGALRVGSQACTDATGCVCGNAETLPWICASLLQPLGGRCPEATCQDPVRPQGQCCDLCGAIVSLTHDPTFDLER--YRARLLDLFLKQPQYQGLQVAVSKV----------LRDAHTEIQVVLLETRP---ATGAAGQLGHALLQDAVAQGSVLGIVSATLRQSGKPTAANSALDQNGSGAG-------LAGGVAAVVLLALVGTVLL--LLHRSGRLRWRRH------------GDAEPTSAGLPLG------------------------FRNPIFDVM-VFKQQQASVEFADSTQKVDILDID-TNFGCFVN-----PLFAGEAEAEA-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99JB7-1", "uniprot_id": "AMNLS_MOUSE", "id": "Q99JB7-1", "name": "Protein amnionless", "aln": "MGALGR-VLLWLQLCAMTRAAYKLWVPNTSFDTASNWNQNRTPCAGDAVQFPADKMVSVLVRDSHAISDMLLPLDGELVLASGAALSAAGGDSDPACNPGAPLLFRNPDRFSWLDPHLWSSGT------QAPGLFSVDAERVPCSYDDVLFPRDGSFRVALGPGPNPVHVRSVSAVGQTFSRDEDLTAFLASREGRLRFHGSGALRVGSQACTDASGCVCGNAEMLPWICASLLQPLGGRCPQAACQDPLLPQGQCCDLCGAIVSLTHDPTFDLER--YRARLLDLFLKQPQYQGLQVAVSKV----------LRDAHTEIQVVLVETEH---ATGAAGQLGHALLQDAVAQGSVLGIVSATLRQSGKPMTADSELNQSSSGAG-------LAGGVAALVLLALLGTVLL--LLHRSGRLRWRRH------------EDAEPVSAGLPLG------------------------FRNPIFDAI-VFKQQ-PSVELPDSAQKVDILDID-TKFGCFVN-----PLFAGEAEAEA-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BXJ7-1", "uniprot_id": "AMNLS_HUMAN", "id": "Q9BXJ7-1", "name": "Protein amnionless", "aln": "MGVLGR-VLLWLQLCALTQAVSKLWVPNTDFDVAANWSQNRTPCAGGAVEFPADKMVSVLVQEGHAVSDMLLPLDGELVLASGAGFGVSDVGSHLDCGAGEPAVFRDSDRFSWHDPHLWRSGD------EAPGLFFVDAERVPCRHDDVFFPPSASFRVGLGPGASPVRVRSISALGRTFTRDEDLAVFLASRAGRLRFHGPGALSVGPEDCADPSGCVCGNAEAQPWICAALLQPLGGRCPQAACHSALRPQGQCCDLCGAVVLLTHGPAFDLER--YRARILDTFLGLPQYHGLQVAVSKVPRSS-----RLREADTEIQVVLVENGP---ETGGAGRLARALLADVAENGEALGVLEATMRESGAHVWG-------SSAAG-------LAGGVAAAVLLALLVLLVAPPLLRRAGRLRWRRH------------EAAAP--AGAPLG------------------------FRNPVFDVT-ASEEL----PLPRRLSLVPKAAADSTSHSYFVN-----PLFAG-AEAEA-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QAN8-1", "uniprot_id": "A0A8M9QAN8_DANRE", "id": "A0A8M9QAN8-1", "name": "Protein amnionless", "aln": "MMALGHNVLLFFCISPFANALYKQWIPDTNFENATNWDKGSVPCGNDQVEFLANRKVSVYVETAHTITGMSLPVDGELILASGAGFTVREGG-DPGCGSGVTAQFKDSESLKWFDPSLWVAATTIDDLHRGTFQFSVHEESVPCQNDDVVFRDATSFRVEISS-DHDVPVKSVSVLGKKFTSSSEFSQYLSSSSGKLQFHGTATISISSSGCGEISGCICDNSRNREKICAN------VRCDTLECKKPLHALGHCCNVCGALVYVQFSSSFNFES--YRQRLQHLFLNTDKYRSVQMAMSKVSREQRLLGVIPFGATQEIQVLLLDQKTGLESGNLAETLARDIMKDVHNHGSNVGISSAEFQASSGASSSDVAGNSAGVVAGAVLGCLVILGLLAGFILLYRRGVVKLPRMPSIPSLSKWRNG------------SDIGELGGPMDHG------------------------FDNPMFDKP-TMMPEQPELYGSETMNSVVLTKSG----VHFVN-----PVYDETDFNG------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VPN2-1", "uniprot_id": "AMNLS_DROME", "id": "Q9VPN2-1", "name": "Protein amnionless", "aln": "-MGLHWQWLIWALVGLHVALATKWYGGGMDFNDPTAWLDDHLPCAQDLVVFPEYYPALLPLPEDISIDGLVFPREGAILLAEESTITFGSDKQPSCESDENKAYLKPPKSSKWFDPGTWTDKS------KEFSTFTPELERIPCDDEQVIIKGHGPLAFDLEN-VQYLRLGQLILAGSSISKT-YLEQLISRDLGQFLFYNAEYVQVEYY-RGELCGCHKDFERLLEPVCHN----VQEQCETPHCLSPVRPLGSCCLICGAILSTPTTHCTEGSRKELVAQISNLISQESLKDQIGLHVEFVG---------SQKFGNCLQAVVTDRHK---YSERSLEFLQQNEHNWNKTGTTLKVSGRPYNPN-VSFSSIVLILFCMALVG------LVSVVILAHFMPENPYLNRIPQWIHDPRLWRWRHLGLRLRRNLLFNRFDNGGAEGGSSEGGASGVDRLGIMAYDPESGEVRERAFDNPMFEQGGALEEAAKESQEQDEILSVPKMETGDLDARSVVDEQELTEINLETCEADTDEETI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *:: : . * : . .*: .: * .. **. . * * . : : :: .: :* :* ::**. : : . :: .. .* ** * . * . * :** ::*.: .: . : : : .: * .:: : :: *:: *:.. : : : ** . . :* :* * ..: . * ** :***:: : . :: . : : : :. * :*.:: : : : : : * : : . . . .* : : . .: . :**. . * * **:*: . * . .*: : ", "identical_positions": 49, "similar_positions": 115, "identity": "9.11%" }, { "cls_id": "homologset.agr.RGD:1308635", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZWJ1-1", "uniprot_id": "D3ZWJ1_RAT", "id": "D3ZWJ1-1", "name": "", "aln": "MQPNKMTSELSLLVGCASGVTPGGDRMQRAGGGWKLKRAASGRCAHFQNGGYSFSCTGRCKKRWPRIVVVTVPWNGMLRTALSRMPTLLRSVRTRDSGPRQLWDLGARLKTAKRL-RGWAWG----WRSSSSAPGSEHAAALG-------RVKADHYQLVYTCKVCGTRSSKHISKLAYHQGVVIVTCPGCQNHHIIADNLSWFSDLKGK----------RNIEEILAARGEEVRRVCGDGALELILEVAEPP---ATPEGGED--PTHPGKMDQS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D113-1", "uniprot_id": "DNLZ_MOUSE", "id": "Q9D113-1", "name": "DNL-type zinc finger protein", "aln": "----------------------------------------------------------------------------MLRTALSRMPTLLRSVRTRDSGPRRLWDLGARLKTAERL-RGWAWGWASGWRSSSSAPGSGRAAALG-------RVEADHYQLVYTCKVCGTRSSKRISKLAYHQGVVIVTCPGCQNHHIIADNLSWFSDLKGK----------RNIEEILAARGEEVRRVSGDGALELILEAAVPP---DTPEGDED--PPNPGKMGQS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5SXM8-1", "uniprot_id": "DNLZ_HUMAN", "id": "Q5SXM8-1", "name": "DNL-type zinc finger protein", "aln": "----------------------------------------------------------------------------MLRTALRGAPRLLSRVQPRAPCLRRLWGRGARPEVAGRR-RAWAWG----WRRSSSEQGPGPAAALG-------RVEAAHYQLVYTCKVCGTRSSKRISKLAYHQGVVIVTCPGCQNHHIIADNLGWFSDLNGK----------RNIEEILTARGEQVHRVAGEGALELVLEAAGAPTSTAAPEAGEDEGPPSPGKTEPS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1L1P7-1", "uniprot_id": "DNLZ_DANRE", "id": "A1L1P7-1", "name": "DNL-type zinc finger protein", "aln": "---------------------------------------------------------------MNSRLCYLLFRPRLLRSRGAGVLSVPETQRVTLARVRHEESNSAFTNSTLRSDVGHDTG------LGLSFCRSFSTEAIG-------QLQSTHYHLVYTCKVCSTRSMKKISKLAYHKGVVIVTCPGCKNHHVIADNLKWFSDLEGK----------RNIEEILAAKGESVRRVEGSEALEIVNEESRNN-----PDEQKP--AHLSDGSDKT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VXR1-1", "uniprot_id": "Q9VXR1_DROME", "id": "Q9VXR1-1", "name": "DNL-type domain-containing protein", "aln": "----------------------------------------------------------MSALKKFYKISAGVRRGALLTSSRRTQIDALNSPQLQLQVHHFATKTQTAVFSSSNNYTCICRSIHCSKPVDDADKTVATNSIPL-------AKLEAKMQLIYTCKVCQTRNMKTISKLAYQRGVVIVTCEGCSNHHLIADNLNWFTDLDGK----------RNIEEILAEKGEKVVRLT-DGNCEFLPKHD--------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VXQ7-1", "uniprot_id": "Q9VXQ7_DROME", "id": "Q9VXQ7-1", "name": "DNL-type domain-containing protein", "aln": "-------------------------------------------------------MNALRNIFTSRTLNYLRQNGQNAILNATQQQQAVDAVPLTNDAEQHLKSSRPAPLSIPRSILDACHFTAKQFDLGGSTSGNQANGSLSPTTLKRFRRMQRRMELVYRCKLCNTRNTKTISEEAYYSGVVILQCDGCAVDHLIKDNLGLFTGSDGDSSISSGISTSKNIDQVLADRHARVRVIKVNERGELI------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P42844-1", "uniprot_id": "ZIM17_YEAST", "id": "P42844-1", "name": "Mitochondrial protein import protein ZIM17", "aln": "-------------------------------------------------------------------MIPRTRTLLQSKIPITRYFARCWAPRVRYNVCRTLPAAALHTNIIAHN----------------EVKKDDKKVHLG-----SFKVDKPKMMIAFTCKKCNTRSSHTMSKQAYEKGTVLISCPHCKVRHLIADHLKIFHDHHVT------------VEQLMKANGEQVSQDVGDLEFEDIPDSLKDVLGKYAKNNSEN-ASQLPHPSQK-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : : : ** * **. : :*: ** *.*:: * * *:* *:* * . . ::::: . * . * : ", "identical_positions": 19, "similar_positions": 24, "identity": "6.88%" }, { "cls_id": "homologset.agr.RGD:1308636", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z8N2-1", "uniprot_id": "RN187_RAT", "id": "D3Z8N2-1", "name": "E3 ubiquitin-protein ligase RNF187", "aln": "MALPAGPAEAICALCQRAPREPVRADCGHRFCRACVVRFWAEEDGPFPCPECADDCWQRAVEPSRPPLSRRLLALEEAAAAPARDGPASEAALQLLCRADGDPLCSACRMAAGPEPPEWEPRWRKALRGKENKGSVEIMRKDLNDARDLHGQAESAAAVWKGHVMDRRKKALTDYKKLRAFFVEEEEHFLQEAEKDEGASDDDELADPADRFRSLLQAVSELEKKHRNLGLSMLLQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BFX1-1", "uniprot_id": "RN187_MOUSE", "id": "Q8BFX1-1", "name": "E3 ubiquitin-protein ligase RNF187", "aln": "MALPAGPADAICALCQRAPREPVRADCGHRFCRACVVRFWAEEDGPFPCPECADDCWQRAVEPSRPPLSRRLLALEEAAAAPARDGPASEAALQLLCRADGDPLCSACRMAAGPEPPEWEPRWRKALRGKENKGSVEIMRKDLNDARDLHGQAESAAAVWKGHVMDRRKKALTDYKKLRAFFVEEEEHFLQEAEKDEGASEDDELADPADRFRSLLQAVSELEKKHRNLGLSMLLQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5TA31-1", "uniprot_id": "RN187_HUMAN", "id": "Q5TA31-1", "name": "E3 ubiquitin-protein ligase RNF187", "aln": "MALPAGPAEAACALCQRAPREPVRADCGHRFCRACVVRFWAEEDGPFPCPECADDCWQRAVEPGRPPLSRRLLALEEAAAAPARDGPASEAALQLLCRADAGPLCAACRMAAGPEPPEWEPRWRKALRGKENKGSVEIMRKDLNDARDLHGQAESAAAVWKGHVMDRRKKALTDYKKLRAFFVEEEEHFLQEAEKEEGLPED-ELADPTERFRSLLQAVSELEKKHRNLGLSMLLQ", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "********:* ****************************************************.************************************..***:*****************************************************************************************:** .:* *****::**************************", "identical_positions": 223, "similar_positions": 10, "identity": "94.49%" }, { "cls_id": "homologset.agr.RGD:1308637", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8C3X2-1", "uniprot_id": "CC90B_MOUSE", "id": "Q8C3X2-1", "name": "Coiled-coil domain-containing protein 90B, mitochondrial", "aln": "MRSRWIWRFLRPDGGGIRWTSTPHGRLSPALRRGFLTTTTKSDYDRRPVDITPLEQRKLTFDTHALVQDLETHGFDKTQAQTIVSVLSTLSNVSLDTIYKEMVTKAQQEITVQQLMAHLDSIRKDMVILEKSEFANLRAENEKMKIELDQVKQQLTNETSRIRADNKLDINLERSRVTDMFTDQEKQLIEATNEFAKKDTQTKSIISETSNKIDTEIASLKTLMESSKLETIRYLAASVFTCLAIALGFYRFWKEN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4V897-1", "uniprot_id": "CC90B_RAT", "id": "Q4V897-1", "name": "Coiled-coil domain-containing protein 90B, mitochondrial", "aln": "MRNRWIWRFLRPECSGIRWISSPHGRLSPALRRGFLTTTTKSDYDRRPVEITPLEQRKLTFDTHALVQDLETHGFDKGQAQTIVSVLSTLSNVSLDTVYKEMVTKAQQEITIQQLMAHLDSIRKDMVILEKSEFANLRAENEKMKIELDQVKQQLINETSRIRADNRLDINLERSRVTDMFTDQEKQLMEATNEFTKKDMQTKSIISETSNKIDTEIASLKTLMESSKLETIRYLAASVFTCLAIALGFYRFWKEN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9GZT6-1", "uniprot_id": "CC90B_HUMAN", "id": "Q9GZT6-1", "name": "Coiled-coil domain-containing protein 90B, mitochondrial", "aln": "MNSRQAWRLFLSQGRGDRWVSRPRGHFSPALRREFFTTTTKEGYDRRPVDITPLEQRKLTFDTHALVQDLETHGFDKTQAETIVSALTALSNVSLDTIYKEMVTQAQQEITVQQLMAHLDAIRKDMVILEKSEFANLRAENEKMKIELDQVKQQLMHETSRIRADNKLDINLERSRVTDMFTDQEKQLMETTTEFTKKDTQTKSIISETSNKIDAEIASLKTLMESNKLETIRYLAASVFTCLAIALGFYRFWK--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P43557-1", "uniprot_id": "FMP32_YEAST", "id": "P43557-1", "name": "Protein FMP32, mitochondrial", "aln": "---------------------MLKRIVGLPARRCFHRTSFLLGSDFETVHIPNTN--------HFKDLLIENGKFQEDQATTIVEIMTDAIRGGVNHVSQDLAKREKLTQLSYQQRVDFAKLRDQLLSADRSEFHNIQNEYESVKNDLEKLRNKLREEITKTNAGFKLDLSLEKGRIREESSHHDLQIKEID------------------TKIEQEVTNMKMQIDSVKTQVMQWLIGVCTGTFALVLAYMRLLT--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .. . ** * *: . * ..*.*. : * :*. *:: ** ***. :: . .:: : :::..: : * ..: :*.::: ::*** *:: * *.:* :*::::::* .* :: .*. :**:.**:.*: : :.:: *: * .**: *::.:* ::* * :.:::* . :*:.*.: *: . ", "identical_positions": 45, "similar_positions": 89, "identity": "17.58%" }, { "cls_id": "homologset.agr.RGD:1308638", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AXW4-1", "uniprot_id": "PHF7_RAT", "id": "Q6AXW4-1", "name": "E3 ubiquitin-protein ligase PHF7", "aln": "MRTIKEKKEHPRLRKTARTKKVTHRKLSSGPVCLLCFQEPGDPEKLGEFLQKDNLCVHYFCLILSSKLPQKGQPNRGLHGFMPEDIKKEAARASRKVCFVCKRKGAAIRCQKDQCVQNFHLPCGQERGCLSQFFGEYKSYCGKHRPTQNIHQRSFG-ESCVLCCEDLSRAS-----VENIRSPCCSQAIYHRKCIQKYAHTSAKHFFKCPQCNNREEFPQEMLRMGIHIPDRDAAWELEPGAFSELYQRYQHCDAPICLYEQGRDSFEDEGRWRLILCATCGSHGTHRDCSS------LRPNSKKWECNECLPASTEDS----------------------------------------------------------------------------------------------------------VSENLGDTPCCSSTFCPHEPFLRATSLEENPGSSWTNWL---QPSLLEKPESSSGSSCQSWRSKGIKVTKDCKKSK---------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DAG9-1", "uniprot_id": "PHF7_MOUSE", "id": "Q9DAG9-1", "name": "E3 ubiquitin-protein ligase PHF7", "aln": "MKTLKEKNKHPRLRKTIRTKKVTQRKLSSSPVCLLCLQEPGDPEKLGEFLQKDNLCVHYFCLILSSRLPQKGQPNRGLHGFMPEDIKREAVRASKKICFVCKKKGAAIRCQNDQCVQNFHLPCGQERGCLSQFFGEYKSYCRKHRPTQNIHQGSLGEESCVLCCENLSRTS-----VENIQSPCCSQAIYHRKCIQKYAHTSAKHFFKCPQCNNREEFPQEMLRMGIHIPDRDAAWELEPGAFSELYQRYRHCDAPICLYEQGRDSFEDEGRWRLILCATCGSHGTHRDCSS------LRPNSKKWECNECLPASTTS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BWX1-1", "uniprot_id": "PHF7_HUMAN", "id": "Q9BWX1-1", "name": "E3 ubiquitin-protein ligase PHF7", "aln": "MKTVKEKKECQRLRKSAKTRRVTQRKPSSGPVCWLCLREPGDPEKLGEFLQKDNISVHYFCLILSSKLPQRGQSNRGFHGFLPEDIKKEAARASRKICFVCKKKGAAINCQKDQCLRNFHLPCGQERGCLSQFFGEYKSFCDKHRPTQNIQHGHVGEESCILCCEDLSQQS-----VENIQSPCCSQAIYHRKCIQKYAHTSAKHFFKCPQCNNRKEFPQEMLRMGIHIPDRDAAWELEPGAFSDLYQRYQHCDAPICLYEQGRDSFEDEGRWCLILCATCGSHGTHRDCSS------LRSNSKKWECEECSPAAATDY----------------------------------------------------------------------------------------------------------IPENSGDIPCCSSTFHPEEHFCRDNTLEENPGLSWTDWP---EPSLLEKPESSRGRRSYSWRSKGVRITNSCKKSK---------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W5W9-1", "uniprot_id": "Q9W5W9_DROME", "id": "Q9W5W9-1", "name": "", "aln": "----------------------------MVQICVLCLSGERDELIFGTVHVEGNMMVHRNCLYLSSNLIQRGEKKLSIMNFLKEDIEAEVNRCRLLKCCYCRRLGANIWCCKSGCRRTFHTKCGVDNLAQNQFCDTYNSFCHQHVLVPRNRPVFKNDEECLLCAEDVVAKGERFSVVTCLYAPCCRNGWFHRRCLQRYANSSG-YFFKCPLCNNTDVFRRVAY-MGIAVLDQDASWETEPDAFAGQYRRDVNCTAALCVAVSGR----ADTSAMLLYCTSCGANPSHYLCTL------KTLQN--YVCKVCSAVSPEAVPVAESDSDDAGSMDDSAEA--------------------PRPGHLNGDQIQEKLSPSHWDDFGSSDDDAVFQRAFDTKVQSRVVTLSDDQPSTSAGARALADRGTRTFESQGTQTTFLSSVVTSFRSATATATSSTSTSTSTSAS---TLDNQENTEPSTSNGRRPWRPRYVSPPRHVSDSDDDSDEYDSDEY------ESKRRQLTPTAAAPSNGRRLLGSISPEPSTPAPRVLRRRTLANRPSSLANMDISCVANRTRHRLSNHMASRKD---------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VKW2-1", "uniprot_id": "PIE_DROME", "id": "Q9VKW2-1", "name": "Pineapple eye protein", "aln": "------------------------MEDNKELQCLICKYSDTDDLVFGEWMIVRNLQVHYFCLLLSTHLPQRGGDSSGILGFLLRDIREEAAAAEKRKCWYCNKIGASLQCDR--CRSLFHLKCGLENRAVFEFCGQYKSYCYKCRPMDDYKRQLQSNPPRNATCPICFSSIYKVELHCVVYGDCCRLGFAHKKCMRQYALTSG-YYLRCIWCRS-ERFRDSIRLQSVFVPDRDATWEKQRNAYRELHERNLKCDQPNCLCPSGR--TYNRLSWVILCCSSCAATSAHLKCLVGALRLPKKRERTDFKCSMCLDVERRIAEGPARTTEETNADGDNQVDGSFYVQKLGPDAATRSLTQTPVFSEEDESERSSNITVIFSQPKSNATSERLSLSPPQEEMIVEIPDSPEASPKTSIDENHSPQPIARRDTSDSPQPIAASEIPDSPQPTAASEIPDLPQTTAINVNPELTQQTALNTIPHSPQPEASFSTQLVSQTFDCPQPQEQAVAKAPNSPSLPKEDPNTLLVLKSGFQCPGEPFFYLVIYEFEHGTCMGECIGTCVLRFKEDDPRIQDTSQAALERVNITPDDVWCRSEDRGIFEHIEKFHEWYRSEGFS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :* * :* *: ** ** **:.* *:* . .: .*: .**. *. . * *.: ** : * . * ** ** :. . :* . *:*:* : : . . : . ** . *::*:::** :*. ::::* *.. . * .: : *:**:** : .*: :.* :* . *: .** :: *::*.: :* * : : *. * . ", "identical_positions": 59, "similar_positions": 72, "identity": "9.64%" }, { "cls_id": "homologset.agr.RGD:1308639", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QYZ8-1", "uniprot_id": "DKK2_MOUSE", "id": "Q9QYZ8-1", "name": "Dickkopf-related protein 2", "aln": "MAALMRVKDSSRCLLLLAAVLMVESSQLGSSRAKLNSIKSSLGGETPAQSANRSAGMNQGLAFGGSKKGKSLGQAYPCSSDKECEVGRYCHSPHQGSSACMLCRRKKKRCHRDGMCCPGTRCNNGICIPVTESILTPHIPALDGTRHRDRNHGHYSNHDLGWQNLGRPHSKMPHIKGHEGDPCLRSSDCIDGFCCARHFWTKICKPVLHQGEVCTKQRKKGSHGLEIFQRCDCAKGLSCKVWKDATYSSKARLHVCQKI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZN48-1", "uniprot_id": "D3ZN48_RAT", "id": "D3ZN48-1", "name": "", "aln": "MAALMRVKDSSRCLLLLAAVLMVESSQLSSSRAKLNSIKSSLGGETPAQAANRSAGMNQGLAFGGSKKGKSLGQAYPCSSDKECEVGRYCHSPHQGSSACMVCRRKKKRCHRDGMCCPGTRCNNGICIPVTESILTPHIPALDGTRHRDRNHGHYSNHDLGWQNLGRPHSKMPHIKGHEGDPCLRSSDCIDGFCCARHFWTKICKPVLHQGEVCTKQRKKGSHGLEIFQRCDCAKGLSCKVWKDATYSSKARLHVCQKI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UBU2-1", "uniprot_id": "DKK2_HUMAN", "id": "Q9UBU2-1", "name": "Dickkopf-related protein 2", "aln": "MAALMRSKDSSCCLLLLAAVLMVESSQIGSSRAKLNSIKSSLGGETPGQAANRSAGMYQGLAFGGSKKGKNLGQAYPCSSDKECEVGRYCHSPHQGSSACMVCRRKKKRCHRDGMCCPSTRCNNGICIPVTESILTPHIPALDGTRHRDRNHGHYSNHDLGWQNLGRPHTKMSHIKGHEGDPCLRSSDCIEGFCCARHFWTKICKPVLHQGEVCTKQRKKGSHGLEIFQRCDCAKGLSCKVWKDATYSSKARLHVCQKI", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****** **** ***************:.******************.*:******* ************.******************************:****************.**************************************************:**.*****************:********************************************************************", "identical_positions": 246, "similar_positions": 10, "identity": "94.98%" }, { "cls_id": "homologset.agr.RGD:1308642", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "M0R9L0-1", "uniprot_id": "M0R9L0_RAT", "id": "M0R9L0-1", "name": "", "aln": "MPGEATETVPATEQELPQPQAETAVLPMSSALNVTAAPGQPGS--PSPSSLGPQQSPLVTAAHQSSPLP--SSLPSTPFEVPFAQP---ETAVPSGAAPPAPTFLPHLIGPPISPAALALASPVIGPAQKGARSSSAPLSLVALAPHSIQKSSVCPPHPLTLPPSAAGAESGALTSLTASIPLLESKASTSQVPSQGTPNLKGTTTPCPPDVVSAFPSHLENPLASVQPGLTSCPQT-----LSITSP-VKGVPISSALT--QSLLSLNLRGPVSSPP---------------QSTVTPSIPPAASASLGSPLPLLHHSSLDSPVQPPGQSGLTVN-----TTISVDHPFVAASYPPERSAVSPLPSRHELAADSG-----AAPSIDKGSSAVTKETCSSSGSANEAG-TSLSPAAPLTPKSSNAALQPSVTQVPPPQKPGLKETPASCIRAMHPALDNPSTMSVAP------ATHVSPPASSGLIKSEDPASPVSSLSVPAAHKPFPAPSMSTTLGIPVSP-LPATEGLQNLPIS--VN--------------AGAPVSPAQAGLPIRKDTTVQTLAPVALKESPSSQSASS---LEVLSED--TKKTTGGPAPVVRPAIATGAPTTLDYPPAGYVNPNPVSQPLKSSAPAMAPFLSESCDSKGLVPRTAKDTFPSVNSPLVPLPSEGCPVAPS------MALSHQNASVSVTT-------AKSVPFP--APPSAGVSFSSAKKVDVVSQMESSDSSQEGHPNASVSSQTKRPASKKGSFPSDVSPGN------VSSPHCSLETSFLPEAGLSFQGPKG----------------------------ASIVPTETSVSSKKTPAEILPSPQKTPTATASRLTSAVQSPKLDPTVSDVIP-------ATVVPRDTSASLSLKSVPAVTSLSSQKAPAAPSPNEALVAPTEIPTSLKNALATTAPKETLATSTLKVASTAPVVTSPSPQKTPKSVSPKGAPAVTS-----KKAKEIAASKEVSTSQFPKEAPLLPHAAPTSPPKSPATDPLNGALTSPSPKVAPATLVESPTSPKKAPKTAAPKETPVTPSLEGVTAVPLEINPCPKKAPKTSTPKESSVTLSSKRTPKSAVSKEIPSNEVTAVPLEISLPLKETSKSAIPVEKSTSSSKSSPKTVAPKETLPEEVTAVPLEVSLPPKEMPQNASP------------------RETPPEGVTAVPLEIPPTPKKAPKTSVPKQIPVTPSPKDAFTTLAESPPSPKKAPTTAAPKEVPAAPSVGITAVS-EISPSPKKTSKTAVPKEDSATSYPKRSPKTATPKENSTSSPKRSPKIEAPKETLATSPEGVTAMPLEIPPSPAAPASKRVPVTPSPKGASNTLAESSASPKKAPKTAAPKETS-TPSPQKIPKMSGPKETPATPPSKKSPKTVAPKETSAPSEGVTALPLKVPPSPRKAPKTAVPKETPAPSP-EGVTTALVQIPPSPRK-VKRTSSKETPTNPSPEGVTAAPLEIPLTSKKNPKMASPKEMLVTPPSKKVSQTGDPKETPPEGVTAVPLEILPSPKKTPKTVVP--KQVPVTPSPKDAPTTLAESPPSPKKAPTTAAPPSERVTTAPPEKPATPQKASATVASKVLVPAETLEVAVSPKET----------HPSSHKKTPKTVDLKEGPAALPPSPTKSPKISSSKKAQNTSAPIEFPASSSIKAVTTSLAQTVP-CVQKAPSTIAPQENSAAPVAIPVSNKSPAAPTTANASVALAAASLSPTPQVKISPSKKTPATSALQTVPKEATTIPSGKKAPAIETSNETSTTLSLKGAPKETSETSTSKGVLTSTVNSSSPKKVPSS---KRASTLPATTLPSIKEASVLSPVPTSSTKDSHTYPVSTACSTATTTPQASEKLPAKKEPAALTEVPAAPAPESALAITVPIQKVPRTKRNSAS-PPKCPDPSAKKDTKGLLSAVALAPQTVPVEKNSSKPIEVLPLCPAKGSDSVHSPKGPME---SQEATPQAAFTSDKVLPKAVSKSVAPKPTLAASLTLAPSPVPPLPPKQPFLQSAPESVLESPSKLPVPADEDELPPLIPPEAVSGGVPFQPILVNMPTPKPAGIPAPAPSAKQPVLKNNKGSGTESDSDESVPELEEQDSTQTATQQAQLAAAAEIDEEPVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPASDTYIVFGEAKIEDLSQQAQLAAAEKFKVQGEA----------------VSNIQENTQTPTVQEESEEEEVDETGVEVKDIELVMSQANVSRAKAVRALKNNSNDIVNAIMELTM-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70670-1", "uniprot_id": "NACAM_MOUSE", "id": "P70670-1", "name": "Nascent polypeptide-associated complex subunit alpha, muscle-specific form", "aln": "MPGEATETVPATEQELPQPQAETAVLPMSSALKVAAV-GQPGP--TPPSSLGPQQSPIVT-AHQPSPLP--SSVSSTPFEVPFAQPITAETALPSGTAPPTPTFLPHLIGPPISPAALALASPMIGLAQKGARSSSAPLSLVALAPHSVQKSSVCPPHPLTSPPSAAGAELGALT---ASIPPLEPKTSTSQVPSQGTLNLKG-TAPCPPDVVRAFPSHLENPLASVQPGLMSCPQT-----LSNTSP-VKGVPISSALT--QSRLSLNLKGPVSPPA---------------RNTAAPSIPLAPSTSLGCHLPLLHHSSVDSPIQPPGQSGLAVS-----NPTSVGHSGIAASCPPERCVVPALPSR-LLAVDSG-----AAPSDDKGSSAVTNELCSPPGSSNVAG-TSLSPKASLVPKGSNVALQPLVTQVPASQKTGLKEIPVSCIGATHHALDNPSAISVAP------ATHVPPPTSSGLVSSKDPASPVTSLVVPAAHKQFPAPPASATLGVPVSP-LPATEGLKNLPISALVN--------------VGAPVSPAQAGLPTRKDTTLQPLAPIALKESPSSQSASS---LEVLSEDTVTKKTTGGPAPVVRPAIAGVATTTSLRADS---PPAVIRADSCVSPNTVSQPLKRSVTDPAMAPRTAKNTAPSTTSPLVPLASEGCPVASS------MALSPQNASVSETALALSPEIPKSVPFP--DPPLAEISFSNARKVDAVSHMESSGSSRQGHPDASVTAKGTVVCLADSSLDTSVSASKGSALSGASSPLYPLEVSFLPEAGLAVQGPKGSLNKLSPTPPSSKGAPVPSTGAPPSPKGAPIVPTESSISSKQVPAEILPSPQKTPEVTASRLISAVQSPKVDPIMSDVTPTSPKKTSATAVPKDTSATLSLKSVPAVTSLSPPKAPVAPS-NEATIVPTEIPTSLKNALAAATPKETLATS-------IPKVTSPSPQKTPKSVSLKGAPAMTS-----KKATEIAASKDVSPSQFPKEVPLLPHVPPTSPPKSPVSDTLSGALTSPPPKGPPATLAETPTYPKKSPKPAASKKTPATPSPEGVTAVPLEIPPCSKKAPKTAAPKESSATSSSKRAPKTAVSKEIPSKGVTAVPLEISLPLKETSKSATPGEKSASSPKRSPKTAGPKETPPGGVTAVPPEISLPPKETPQNATPNESLAASSQKRSPKTSVPKETPPGGVTAMPLEIPSAPQKAPKTAVPKQIPT---PEDAVTILAGSPLSPKKASKTAAPKEAPATPSVGVIAVSGEISPSPKKTSKTAAPKENSATLPPKRSPKTAAP-----------------KETPATSSEGVTAVPSEISPSPPTPASKGVPVTLTPKGAPNALAESPASPKKVPKTAAPEETSTTPSPQKIPKVAGPKEASATPPSKKTPKTAVPKETSAPSEGVTAVPLEIPPSPRKAPKTAAPKETPAPSP-EGATTAPVQIPPSPRKGSKKAGSKETPTTPSPEGVTAAPLEIPISSKKTSKMASPKETLVTPSSKKLSQTVGPKETSLEGATAVPLEIPPSHKKAPKTVDP--KQVPLTPSPKDAPTTLAESPSSPKKAPKTAAPPSERVTTVPPEKPATPQKASATTASKVPVPAETQEVAVSSRETPVTPAVPPVKNPSSHKKTSKTIELKEAPATLPPSPTKSPKIPSSKKAPRTSAPKEFPASPSIKPVTTSLAQTAPPSLQKAPSTTIPKENLAAPAVLPVSSKSPAAPAAASASLS--------------------PATAAPQTAPKEATTIPSCKKAAATETPIETSTAPSLEGAPKETSETSVSK-----VLMSSPPKKASSS---KRASTLPATTLPSLKEASVLSPTATSSGKDSHISPVSDACSTGTTTPQASEKLPSKKGPTAFTEMLAAPAPESALAITAPIQKSPGANSNSAS-SPKCPDPSSKKDTKGLPSAVALAPQTVPVEKDTSKAIETLLVSPAKGSDCLHSPKGPVG---SQVATPLAAFTSDKVPPEAVSASVAPKPAPAASLTLAPSPVAPLPPKQPLLESAPGSVLESPSKLPVPAEEDELPPLIPPEAVSGGEPFQPILVNMPAPKPAGTPAPAPSAKQPVLKNNKGSGTESDSDESVPELEEQDSTQTATQQAQLAAAAEIDEEPVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPASDTYIVFGEAKIEDLSQQAQLAAAEKFKVQGEA----------------VSNIQENTQTPTVQEESEEEEVDETGVEVKDIELVMSQANVSRAKAVRALKNNSNDIVNAIMELTM-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8JIU7-1", "uniprot_id": "NACA_DANRE", "id": "Q8JIU7-1", "name": "Nascent polypeptide-associated complex subunit alpha", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPGEATETVPVTEQEMQQPQAET--GSGTESDSDESVPDLEEGDSAQTQTQQAQLAAAAEIDEEPVSKAKQSRSEKKARKAMSKLGLRQVAGVTRVTIRKSKNILFVITKPDVYKSPASDTYIVFGEAKIEDLSQQAQLAAAEKFKVQGEA----------------VSNIQENTQTPTVQEESEEEEVDETGVEVKDIELVMSQANVSRAKAVRALKNNNNDIVNAIMELTM-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E9PAV3-1", "uniprot_id": "NACAM_HUMAN", "id": "E9PAV3-1", "name": "Nascent polypeptide-associated complex subunit alpha, muscle-specific form", "aln": "MPGEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSA-ANQASPFPSPSTIASTPLEVPFPQS-SSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKG--TPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGS-VQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPNATY---------HYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKE-PSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSAS------VIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGT-------LTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALA-------PVASSPKECPTEDSGASATASSKG---------------------------------TLTYLADSPSPLGVSVSPQ--TKRPPTKKGSAGPDTPIGNLSSPVSP-----VEASFLPENSLSFQGSKDSPATT-----HSPTPPSPKGAPTPSAVTPLSPK--GVTLPPKETPTPS---------VVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPAT---------PSPKWAPTPPAATPPSPKGG---------PATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTP------PAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATP---SLKGAPTPPAATP--------------------PSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAA--------TPPSPKGGLATPPPK--GAPTTPAATPPSPKG------------------GLATPSPKGAPTTPAATPPSP-----KGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAAT----PPSPKGGPATPPPKGAPTPPAATPPSLKG-GLATPPHKGAPNP-AVVTPPSPKGGPATSPPKGAPTPPAATPPSPKG---------SPGTPPPKGAPTPPAVTPPSPKGTPTLPAT-----TPSSKGGPTTPSSKEGPT------PPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTR---------EGAATPSKGDLTPPAVTPVSLKKAPATSA---------------PKGGPATPSSKGDPTLPAVTPPSPKEPP---APKQVATSSSPKKAPATPAPMGAPT-LPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIP--------------------PAMTVPS--PKKTPAIPTPKEAPATPSSKEASSPPAVT-PSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAP-LLPVQKDSSK--------TAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPELEEQDSTQATTQQAQLAAAAEIDEEPVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPASDTYIVFGEAKIEDLSQQAQLAAAEKFKVQGEA----------------VSNIQENTQTPTVQEESEEEEVDETGVEVKDIELVMSQANVSRAKAVRALKNNSNDIVNAIMELTM-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q94518-1", "uniprot_id": "NACA_DROME", "id": "Q94518-1", "name": "Nascent polypeptide-associated complex subunit alpha", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPELTEIKSEAAPSTSAEAK-PEDVRVEDDGSDSDSDGGMPGLEE--AVAATTQLGGGATGLPID--LVSKAKQSRGEKKARKIMLKLGLKQIQGVNRVTIRKSKNILFVINNPDVYKNPHSDTYIVFGEAKIEDLSQQAQVAAAEKFKAPEAAG--------------AADSVGATTSVAPIAEE-DEEDVDDTGVDEKDIELVITQANTTRAKAIKALKNNNNDIVNAIMELTML", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38879-1", "uniprot_id": "NACA_YEAST", "id": "P38879-1", "name": "Nascent polypeptide-associated complex subunit alpha", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSAIPENANVTVLNKNEKKARELIGKLGLKQIPGIIRVTFRKKDNQIYAIEKPEVFRS-AGGNYVVFGEAKVDNFTQKLAAAQQQAQASGIMPSNEDVATKSPEDIQADMQAAAEGSVNAAAEEDDEEGEVDAGDLNKDDIELVVQQTNVSKNQAIKALKAHNGDLVNAIMSLSK-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. : .:.*****: : ****:*: *: ***:**..* ::.* :*:*::. ...*:******:::::*: * : . . : .. *: :* :** .:: .*****: *:*.:: :*::*** :..*:*****.*: ", "identical_positions": 51, "similar_positions": 59, "identity": "2.17%" }, { "cls_id": "homologset.agr.RGD:1308643", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q6V9R5-1", "uniprot_id": "ZN562_HUMAN", "id": "Q6V9R5-1", "name": "Zinc finger protein 562", "aln": "MSAFDMSHGFFPREPICPFEEKTKIGTMVEDHRSNSYQDSVTFDDVAVEFTPEEWALLDTTQKYLYRDVMLENYMNLASVDFFFCLTS-------------------EWEIQPRTKRSSLQQGFLKN----QIFTG---IQMQTRSYSGWKLCEN--CGEVFSEQFCLKTHMRAQNGGNTFEGNCYGKDSISVHKEASIGQELSKFNPCGKVFTLTP-------------------------------------------------------GLAVHLEILNGRQPYKCKECGKGFKYFASLDNHMGIHIGEKLCEFQECERAITTSSHLKQCVAVHTGKKSEKTKNCGKSFTNFSQLSAHAKTHKGEKSFECKECGRSFRNSSSFNVHIQIHTGIK----------------------------PHKCTECGKAFTRSTHLTQHVRTHTGIKPYECKECGQAFTQYTGLAIHIRNHTGEKPYQCKECGKAFNRSSTLTQHRRIHTGEKPYECVECGKTFITSSHRSKHLKTHSGER-------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1MAL0-1", "uniprot_id": "F1MAL0_RAT", "id": "F1MAL0-1", "name": "", "aln": "MAAIDLSHGLLPREPIYVYEANIEVEGTVTDNQANCYQDSVTFDDVAVEFTPDEWTLLDLTQKNLYREVMLENYENLTSVGCQFFIPSLTPWLKQEELGVAESALPQQLELQPTIDDSELENYFRMQSSSATEMVGDSSLQEQSGNHSEGDLRDSKPCGNVLGEQLCLNTEVSTQSQGYSSECNWYGKDILSLLKETSTGQNVSELNQCGKLFSLTPNIMYPSTSTNEKPFECTDCETAFFNQSYFQPDMRPHNGGEPYDWSKFGNGFIHPTSLAMHLPILNARNPYKFEECGKDFQYFACLNNPMGMCTGEKFCDCKECWKAFTVSSHLTQYVSIHTEEKSKVCKICGKSFANYSRLSAHVKTHNEEKPFVCKECGKAFKNMSYLNDHVRIHTGIKSYKCMECGKAFLRWSGLTEHIRVHTGEKPYECKECGKTFSRSTQLTEHIRTHTGIKPYECKECGKAFTQYSGLATHVRIHSGEKPFACKECGKAFTRTSGLIHHVRTHTGEKPFECVHCGKTFITSSHRTKHLKIHSGEKPFVCNICGKAFIYSTSLNIHMRTHTGEKPYICKQCGKAFAVYSRLRKHSRVHTEEKPYQCEGVGVAT", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:*:*:***::***** :* : :: * *:::*.****************:**:*** *** ***:****** **:**. * :.* : *:** . *.*:: * : :.* :* *: .:* .* :. **:*:.**:**:*.: :*. * : * * **** :*: **:* **::*::* ***:*:*** .**:** ***.*:*** :****.*:***.*:* **: ***:*: :** :*:*.****.* *::** :**: * *****:*:*:****.***: **.* *****::*:* * :* *::****** *::*.****:*:***:**:*:***************:*****:*** *:* *:****: ********.*:* * :* * ******:***.***********:**** ****: ", "identical_positions": 255, "similar_positions": 108, "identity": "42.22%" }, { "cls_id": "homologset.agr.RGD:1308644", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BJS7-1", "uniprot_id": "MAP10_MOUSE", "id": "Q8BJS7-1", "name": "Microtubule-associated protein 10", "aln": "MATTAAGRLFSLELLVDWVRLETGLSPCAAS-----------------------PAVAFRLLDFPPLLVFPP---AAPGPEPQRGAISFGRGKACLLRLHPAALR----RPRLRAALLQLPVG-PTSAPGLVGACDILLVPSLG-------------QRGVFALRGPEAERVGELALFYRLTELGRFSPGVPQLRGPLSPACILDSEALEVSEPRTEETSKPCTKGISARCLQCVSNARLLEGSEPCAKDTNSWSAGDSDASVVQKSWEEAVLHSKASSGDMASAPCSPAPSGKTVSSVSQDVTELDFETNTFCPPPLYYTHLTQEKTPSARVEITIEPQRNEPEDLDDIFPETKLVSPPLRP--VKHTRAAVQESPPVLPNLPQTQGPGEANEAPCPPQIEQSPVNAIRQLPLLNALLIELSLLCNQPVASPTQVHPHLAWLYRGEDK-GPDPSTKSTSPSESKSNKLSVRENEKLVNPQSKKN-----PKGKHP-KIGGSPPPKVTKGRLLYGLTNTLRLRLQQTNPNMLVVHEKREQYRRSQIQAVGPKLRIPSWKGKVSSSAAESQMSPQLPADTPTDSNGKLPSLAVQSQLPPQLPGDESLDSIGSFEEGSDTSMQIRAGFDESSTTKEVKQSHAMKQEMVDQSENRTIVTALRAPVSPAGSVTPERSLRSNSFGGNWKNKVPSPGLSLQEPTVDKTVDEGKDGRQVKAIS----AADTSENRPTSRKSSCESISELLYRDGFTSPCYSEDFCTTENNSRSLPAPDSSTGVEHVQKGSRASKSSEARLSTRKNSSDSSSVLTPPFSAGSPVCSHKRSRALKIHD-SLEEASSLSTSDFSS-QWTNEKENQADPG---SSKVMRKGRDSSTKLKVRAGHKSSEKSQSPRTSQVSSYEPSNLSELELKAIDDSDLAD--FQEEEDGLGSLRISRQCKDICELVINKLPGYTV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZAP3-1", "uniprot_id": "MAP10_RAT", "id": "D3ZAP3-1", "name": "Microtubule-associated protein 10", "aln": "MAATAAERLFSLELLVDWVRLDS---PCFAS-----------------------PAVAFRLLDFPPLLILPP---AAPDPEPQRGAITFGRGKACLLRLRPAALR----RPRLRAALLQLPAV-PTPAPLLLGACDILLVPSVG-------------QRGIFTLRGPEAERVGELALFYRLTDLGRFPPGAPQLRSPLSPACITGSEALEVSEPRTKETSKPCTKDTSARCLQCVSNGRFLEAPEPCAKDTDNWSAGDSDASAVQKSWEEAILHSKASSGDMASAPCSPAPSGRTVSPVSLEVTELDFETNTFCPPPLYYTHLTQEKAPSARVEITIEPQRNEPEDLEDAFPETKPVGPTIRP--VKHTRAAIQESPPVLLNLPQMQGPGEANEAPCPPQTEQSTVGAIRQLPLLNALLMELSLLCNQPVANPSQVHPHLAWLYRGEHK-GPDPSTKSTSRSESKSNKLSAQENEKLVSPQSTKN-----PKGKHS-KISGSPPPKVTKGRLLYGLTNTLRLRLQQTNPGMLVVHEKREQYRRSQIRAVGPKFRIPSWKGKVSSLAAESQMPPQLPGDTLTDSNGKVSSWAVQSQLPPQLPRDRSLDSYGSFAEGSDTSMLISSGFDESSRTREAKQSHAMKKETVGQSENK-TVTSLRAPVSPAVSVIPERSPRSNILRGKWKKQVQSPGLSRQDPAVDKAVGEGIDGKQVKAAS----AADTNENRPPSRKSSCESTSELQCWDGSTSPCYSEDFCTTENNSRSLPAPDSSTGAEYAQKGSWASKSSEARLSTRKNSSESSSVFTPPFSAGSPVCSQKRSRVLKTHD-SLEEASSLSTSDFSS-QWTNEKENQADPG---SSKIRRR-QDRSTKLKVGTGHKSSEKSHSARTSQVSSYEPSNLSELELKAIDDIDSASTGFQEEEDGLGSLRISRQCRDICELVINKLPGYTV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9P2G4-1", "uniprot_id": "MAP10_HUMAN", "id": "Q9P2G4-1", "name": "Microtubule-associated protein 10", "aln": "MAASLSERLFSLELLVDWVRLEARLLPSPAAAVEQEEEEEEKEQGEASSPRGLCPAVAFRLLDFPTLLVYPPDGPGAPAAEPWPGVIRFGRGKSCLFRLQPATLHCRLLRTPLATLLLQLPPGRPTPTPQLLGACDISLATAAHRVVGPAASGCSHRHRGRFPLHNRVGERTGDIALAYRLTDLG--SRLLSQLERPLTFTRTGG--GAEVS-PQTQQERQ--------QLQQPASQPSPKEADKPLG-ELEIPEAQKDLKEMVKSKAECDNVGSVENGKTNSVVTCSGAGNGRNVSSLNEEVTELDMETNIFCPPPLYYTNLTQEKPPPAQAKITIEPQMNAPEEMDDASPEKKRVNPPAHRSCLKHPSSAAHEHPPMLVNPPHIQNIGATNQT---CQTEQNRINTIRQLPLLNALLVELSLLYDQPVTSPAHIHPHLAWLYRTEDKKSPESSAKSTCRSEAKKDKRSVGGCEKSVSLQYKKNQIENYKEDKYSEKSSGALHKRVPKGRLLYGLTNTLRLRLKLTNPDMLVVHEKRELYRKRQSQMLGTKFRIPSSKVKLLSSAEQSQK--------------------------PQLPEDKYLDSDASFTENSDTSRQISGVFDEPSTSKETKLKYATEKKTVDCSKNRINNVSLEEVVSPANSIIPERLTPTNILGGNVEMKIQSPCVFQQDAVVDRIVDKEIDIRQVKTTDNDILMADISDKR-TGKNSCYENISELKYSDDLSSPCYSEDFCTSEDTSRSFKAHDSSSRTENPKHSQYTSKSSDTGVSKKKNSSDRSSILSPPFSAGSPVHSYRKFHISKTQDKSLEEASSISASDLSSTHWTEQKENQIDQNSMHNSEITKRAQDIS--VKTRSSWKSLEKSQSPQTSQVSSYLPSNVSELN--VLDSSTSDH--FEEGNDDVGSLNISKQCKDICELVINKLPGYTM", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:: : **************:: *. *: ***********.**: ** .** .** *.* *****:**:**:**:*: *. * : ***** **.:* *:***** *..: :** *.*:. .**.*::** ****:** . .**. **: : . . *** *:*:: : : * .*: *. :* . : : .* .. . *:.. * : * .. : ..** * .*:.**.:. :*****:*** *********:*****.*.*:.:****** * **:::* **.* *.*. : :**. :* :* **:* * *: *. * :*:: * **. :.:***********:***** :***:.*:::********* *.* .*:.*:***. **:*.:* *. ** *. * .** :.*:. * .*: :*.****************: ***.********* **: * : :*.*:**** * *: * * :** **** *. *** .** *.**** * . ***.* ::*.* .:* ::: *. *:*: .:*. **** *: *** :* : *: : :: ** : *:..**: *.: * :***: . ** .::* ..::*. *. *** *. :**********:*:.***: * ***: .* ::.. :****:: :*.:****: **:::********* * :: : * :* *******:*:**:** :**::**** * . .*:: :: :* * :*. :. ** ***:*.:******* ***:***: .:*. *:* :*.:***.**:**:**************:", "identical_positions": 419, "similar_positions": 241, "identity": "43.87%" }, { "cls_id": "homologset.agr.RGD:1308645", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z0I6-1", "uniprot_id": "SLFN2_MOUSE", "id": "Q9Z0I6-1", "name": "Schlafen family member 2", "aln": "MGTRLEATEQSNHRTQRNDIQLENAKAAGKMGISVDLEAKYAKLGLNLGAITFGEKDRKKMKNSHLRKQENANISLAVCALLNSGGGAIKVKIENENYSLTRDGLGLDLEASLCKCLPFVQWHLDFTESEGYIYIYVKSWSQEIFGLPIGTLRTNLYVRSMSSSVQVSAAAALEFLQDLEETGGRPCVRPELPASIAFPEVEGEWHLEDLAAALFNRTEFQYEETFPFTRSRYVEVTLLSAKRLRKRIKELLPQTVSAFANTDGGFLFIGLDGKTQQIIGFEAEKSDLVLLESEIEKHIRQLPVTHFCEEKEKIKYTCKFIEVHKSGAVCAYVCALRVERFCCAVFAAEPESWHVEGGCVKRFTTEEWVKLQMNAPSG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A2D6-1", "uniprot_id": "D4A2D6_RAT", "id": "D4A2D6-1", "name": "", "aln": "------------------------------MGISVDLEAEYAKLGLNLGAITLGEKDRRKMKNSHLRKKENENISLAVCALLNSGGGAIKVKIENENYSLTRDGLGLDLETSLCKCLPFVQWYLDFTESKGYIYIYVRAWSQEIFGLPIGTLSTNLYVRVVSSSVQVSADAALQFLQDLEEAGGRPRVRPELPARKACPGVEGECHQEDLAAAFFNKTEFQYEETFFFTRSRYVEVTSLSVKRLRKRIREILPRTVSAFANTDGGYLFIGLDGKKQQIIGFEAEKSDLVHLESEIEKCIRQLPVTHFCEEREKIKYTCKFMEVHKPGAACSYVCALRVERFCCAVFAAEPESWHVEDSCVKRFAAEDWVRLQMGSREAWKR----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6IEE8-1", "uniprot_id": "SN12L_HUMAN", "id": "Q6IEE8-1", "name": "Schlafen family member 12-like", "aln": "------------MDLARKEFLRGNGLAAGKMNISIDLDTNYAELVLNVGRVTLGENNRKKMKDCQLRKQQNENVSRAVCALLNSGGGVIKAEVENKGYSYKKDGIGLDLENSFSNMLPFVPNFLDFMQNGNYFHIFVKSWSLETSGPQIATLSSSLYKRDVTSAKVMNASAALEFLKDMEKTGGRAYLRPEFPAKRACVDVQEESNMEALAADFFNRTELGYKEKLTFTESTHVEIKNFSTEKLLQRITEILPQYVSAFANTDGGYLFVGLN-EDKEVIGFKAEKSYLTKLEEVTKNSIGKLPVHHFCVEKGTINYLCKFLGVYDKGRLCGYVYALRVERFCCAVFAKKPDSWHVKDNRVKQLTEKEWIQFMVDSEPVCEELPSPASTSSPVSQSYPLREYINFKIQPLRYHLPGLSEKITCAPKTFCRNLFSQHEGLKQLICEEMGSVNKGSLIFSRSWSLDLGLQENHKVLCDALLISQDKPPVLYTFHMVQDEEFKDYSTQTAQTLKQKLAKIGGYTKKVCVMTKIFYLSPEGKTSCQYDLNSQVIYPESYYWTTAQTMKDLEKALSNILPKENQIFLFVCLFRFCLFVCWFVCFFLR", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.**:**:::**:* **:* :*:**::*:***:.:***::* *:* ***********.**.::**:.** .:**:***** *:.: **** .*** :. .*::*:*::** * * *.** :.** * ::*: :.* ***:**:*:*::***. :***:** * *: * : * *** :**:**: *:*.: **.* :**:. :*.::* :** *:**: **********:**:**: : :::***:**** *. **. :: * :*** *** *: .*:* ***: *:. * *.** ************* :*:****:.. **::: ::*::: :.: ", "identical_positions": 174, "similar_positions": 110, "identity": "28.95%" }, { "cls_id": "homologset.agr.RGD:1308647", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4AC89-1", "uniprot_id": "D4AC89_RAT", "id": "D4AC89-1", "name": "Ankyrin repeat- and BTB/POZ domain-containing protein 3", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MARRGKKPVVRTLEDLTLDSGYGGAADSVRSSN----------------------------------------------------------------------------------------------------------LSLCCSDSHPASPYGGSCWPPLADSMHSRHNSFDTVN-------------------------------------------------------------TALVEDSEGLDCAGQHCSRLLPDLDEVPWTLQELELLLLRSRDPRAGPAAPGSLPKDALAKLSMLVSRALVRIAKEAQRLSLRFAKCTKYEVQSAMEIVLSWGLAARCTAAALAALSLYNMSSAGGDRLGRGKSARCGLTFSVGRVYRWMVDSRVALRIHEHAAIYLTACMESLFRDIYTRVLASGLPRSCSGPGPGSSSSSGPGPGSGPG-APTADKERETPGGGAASGGPCSAASSASGGSSCCAPPATAATAVPPATATAAAPTAANHHHHHHHHTLHEAPKFTVETLEHTVNNDSEIWGLLQPYQHLICGKNASGVLSLPESLNLHRDPQRPSKPGELPMFSQSELRTIEQSLLATRVGSIAELSDLVSRAMHHLQPLNVKHHGNGTPLHH-KQGALYWEPEALYTLCYFMHCPQMEWENPNVEPS---KVNLQVERPFLVLPPLMEWIRVAVAHAGHRRSFSMDSDDVRQAARLLLPGVDCEPRQLKADDCFCASR---------------------------------KLDAVAIEAKFKQDLGFRMLNCGRTDLVKQAVSLLGPDG-INTMSEQGMTPLMYACVRGDEAMVQMLLDAGADLNVEVVSS-PHKYPSVHPETRHWTALTFAVLHGHIPVVQLLLDAGAKVEGSVEHGEENYSETPLQLAAAVGNFELVSLLLERGADPLIGTMYRNGISTT---PQGDMNSFSQAAAHGHRNVFRKLLAQPEKE-KSDILSLEEILAEGTDLAETAPPPLCAS-----------------RNSKAKLRALREAMYHSAEHGYVDVTIDIRSIGVPWTLHTWLESLRIAFQQHRRPLIQCLLKEFKTIQEEEYTEELVTQGLPLMFEILKASKNEVISQQLCVIFTHCYGPYPIPKLTEIKRKQ---TSRLDPHFLNNKEMSDVTFLVEGRPFYAHKVLLFTASPRFKALLSSKPTNDS--TCVEIGYVKYPIFQLVMQYLYYGGPESLLIKNNEIMELLSAAKFFQLEALQRHCEIICAKSVNTDNCVDIYSHAKFLGVTELSAYCEGYFLKNMMVLIENEAFKQLLYDKNGEGTGQ----DVLQDLQRTLAIRIQSIHLSSSKGSVV------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6GQW0-1", "uniprot_id": "ABTB3_MOUSE", "id": "Q6GQW0-1", "name": "Ankyrin repeat- and BTB/POZ domain-containing protein 3", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MARRGKKPVVRTLEDLTLDSGYGGAADSVRSSN----------------------------------------------------------------------------------------------------------LSLCCSDSHPASPYGGSCWPPLADSMHSRHNSFDTVN-------------------------------------------------------------TALVEDSEGLDCAGQHCSRLLPDLDEVPWTLQELELLLLRSRDPRAGPAVPGSLPKDALAKLSMLVSRALVRIAKEAQRLSLRFAKCTKYEIQSAMEIVLSWGLAAHCTAAALAALSLYNMSSAGGDRLGRGKSARCGLTFSVGRVYRWMVDSRVALRIHEHAAIYLTACMESLFRDIYSRVLASGLPRSCSGPGPGSSSGSGPGPGSGPG-APAADKERETPGGGAASGGPCSAASSASGGSSCCAPPATAATAVPPTTATAAV--AAN--HHHHHHTLHEAPKFTVETLEHTVNNDSEIWGLLQPYQHLICGKNASGVLSLPESLNLHRDPQRPSKPGELPMFSQSELRTIEQSLLATRVGSIAELSDLVSRAMHHLQPLNAKHHGNGTPMHH-KQGALYWEPEALYTLCYFMHCPQMEWENPNVEPS---KVNLQVERPFLVLPPLMEWIRVAVAHAGHRRSFSMDSDDVRQAARLLLPGVDCEPRQLKADDCFCASR---------------------------------KLDAVAIEAKFKQDLGFRMLNCGRTDLVKQAVSLLGPDG-INTMSEQGMTPLMYACVRGDEAMVQMLLDAGADLNVEVVST-PHKYPSVHPETRHWTALTFAVLHGHIPVVQLLLDAGAKVEGSVEHGEENYSETPLQLAAAVGNFELVSLLLERGADPLIGTMYRNGISTT---PQGDMNSFSQAAAHGHRNVFRKLLAQPEKE-KSDILSLEEILAEGTDLAETAPPPLCAS-----------------RNSKAKLRALREAMYHSAEHGYVDVTIDIRSIGVPWTLHTWLESLRIAFQQHRRPLIQCLLKEFKTIQEEEYTEELVTQGLPLMFEILKASKNEVISQQLCVIFTHCYGPYPIPKLTEIKRKQ---TSRLDPHFLNNKEMSDVTFLVEGRPFYAHKVLLFTASPRFKALLSSKPTNDN--TCIEIGYVKYPIFQLVMQYLYYGGPESLLIKNNEIMELLSAAKFFQLEALQRHCEIICAKSINTDNCVDIYSHAKFLGVTELSAYCEGYFLKNMMVLIENEAFKQLLYDKNGEGAGQ----DVLQDLQRTLAIRIQSIHLSSSKGSVV------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6QL63-1", "uniprot_id": "ABTB3_HUMAN", "id": "A6QL63-1", "name": "Ankyrin repeat- and BTB/POZ domain-containing protein 3", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MARRGKKPVVRTLEDLTLDSGYGGAADSVRSSN----------------------------------------------------------------------------------------------------------LSLCCSDSHPASPYGGSCWPPLADSMHSRHNSFDTVN-------------------------------------------------------------TALVEDSEGLDCAGQHCSRLLPDLDEVPWTLQELEALLLRSRDPRAGPAVPGGLPKDALAKLSTLVSRALVRIAKEAQRLSLRFAKCTKYEIQSAMEIVLSWGLAAHCTAAALAALSLYNMSSAGGDRLGRGKSARCGLTFSVGRVYRWMVDSRVALRIHEHAAIYLTACMESLFRDIYSRVVASGVPRSCSGPGSG--SGSGPGPSSGPGAAPAADKEREAPGGGAASGGACSAASSASGGSSCCAPPAAAAAAVPPAAA-------AN-HHHHHHHALHEAPKFTVETLEHTVNNDSEIWGLLQPYQHLICGKNASGVLCLPDSLNLHRDPQRSNKPGELPMFSQSELRTIEQSLLATRVGSIAELSDLVSRAMHHLQPLNAKHHGNGTPLHH-KQGALYWEPEALYTLCYFMHCPQMEWENPNVEPS---KVNLQVERPFLVLPPLMEWIRVAVAHAGHRRSFSMDSDDVRQAARLLLPGVDCEPRQLRADDCFCASR---------------------------------KLDAVAIEAKFKQDLGFRMLNCGRTDLVKQAVSLLGPDG-INTMSEQGMTPLMYACVRGDEAMVQMLLDAGADLNVEVVST-PHKYPSVHPETRHWTALTFAVLHGHIPVVQLLLDAGAKVEGSVEHGEENYSETPLQLAAAVGNFELVSLLLERGADPLIGTMYRNGISTT---PQGDMNSFSQAAAHGHRNVFRKLLAQPEKE-KSDILSLEEILAEGTDLAETAPPPLCAS-----------------RNSKAKLRALREAMYHSAEHGYVDVTIDIRSIGVPWTLHTWLESLRIAFQQHRRPLIQCLLKEFKTIQEEEYTEELVTQGLPLMFEILKASKNEVISQQLCVIFTHCYGPYPIPKLTEIKRKQ---TSRLDPHFLNNKEMSDVTFLVEGRPFYAHKVLLFTASPRFKALLSSKPTNDG--TCIEIGYVKYSIFQLVMQYLYYGGPESLLIKNNEIMELLSAAKFFQLEALQRHCEIICAKSINTDNCVDIYNHAKFLGVTELSAYCEGYFLKNMMVLIENEAFKQLLYDKNGEGTGQ----DVLQDLQRTLAIRIQSIHLSSSKGSVV------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LVW0-1", "uniprot_id": "ABT3A_DANRE", "id": "Q1LVW0-1", "name": "Ankyrin repeat- and BTB/POZ domain-containing protein 3-A", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAGKGK-TAARTLEDLTLDSGYGGAADSFRSSS----------------------------------------------------------------------------------------------------------VSLCCSDTHLSYAHGGNCWH-LTESMHSRHNSLDTVN-------------------------------------------------------------TVLAEDTEILECSG-QCAKLPELEEDVPWSLGEVEGALRKDEELCVG-----NASREILAKLSALVSRALVRIAREAQRMSLRYARCTKHEIQSAIKMVLSWTISVNCITAALSALSLYNMSTG--DKFSRGKSTRCGLIFSVGKFFRWMVDSRVALRIHEHAAIYLSACMESLFREVFTRVQRSALVEKENG-----------------------------------------------------------------------------------------VPKFSVESLEQAINNDSELWGLLQPYQHLICGKNASGVLSLPDSLNLHRDQQRAGKTGEGHAYSQAELRTIEQSLLATRVGSIAELSDLVSRAMHHLQPLHIKNPSNGTPVHQNRTGSVHWEPEALYTLCYFMHCPQMEWENPNVEPS---KITLHTERPFLVLPPLMEWIRVAVAHTEHRRSFSVDSDDVRQAARLLLPGVDCEPRQLKADDCFCATR---------------------------------KLDAASTEAKFLQDLGFRMLNCGRTDLVKQAVNLLGPDG-INSMSEQGMTPLMYSCVRGDEAMVQMLLDAGADINSEVPSS-LHKHPSVYPDTRQGTPLTFAVLHGHVPVVQLLLDARANVEGAIQESTENYTETPLQLASAAGNFELVSLLLERGADPLIGTTYRNGISSG---PLGEMNSYSLAAAHGHRNVFRKLLSQVEKD-KGDVLSLEEMLAEGSEAVERRAPQNEGTL----------------RTGKAKLRALREAMYHSAEHGHVDITIDIRSLGVPWTLHTWLESLRTCFVQQRRPLIQGLLKDFSCIKEDEYTEELITHGLPLMFQILRASKNEVISQQLSVIFTQCYGPFPIPKLTEIKKKQ---TSRLDPHFLNNKEMSDVTFLVEGKPFYAHKVLLFTASPRFKSLLSNRPAAEN--TCIEISHVKYNIFQLVMQYLYCGGTESLHIRNTEIMELLSAAKFFQLDALQRHCEIICSKNITNDSCVDIYKHARFLGALELAGFIEGFFLKNMVLLIELENFKQLLYEVPADSPGPGPSYDVLHDLEQTLALRIRSIHLSTSKGSIV------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P0C7A6-1", "uniprot_id": "ABT3B_DANRE", "id": "P0C7A6-1", "name": "Ankyrin repeat- and BTB/POZ domain-containing protein 3-B", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAKRGK-SVVRTLEDLTLDSGYGGAADSFRSSS----------------------------------------------------------------------------------------------------------LSLCCSEAHISYAHGGHCWN-LTDSMRSRHNSLDTVN-------------------------------------------------------------TVLAEDGETLECSG-HCAKLPELED-VPWSLGEVENALNKEEELRFG-----TVSADLLARLSALVCRALVRIAREAQRLSLRYGKCTKYEVQSAIKMILSWTISVNCIAASLSALSMYNMSTE--DKFSRGKSERCGLVFSVGKFFRWMVDSRVAVRVHEHAAIYLTGCMESLFREVFTRVLNSSVVEKDNG-----------------------------------------------------------------------------------------IPKFTLESFEQALSNDSELYGLLLPYQHLTCGKNANGILSLPDSLSLHRNQQCSSKAGD--AYSQSEQRTIEQSLLATRVGSIAELSDLVSRAMHYLQPLSIKNHSNGTPLPQ-KSSLVHWEPEALYTLCYFMHCPQMEWENPNVEPS---KVTLQNERPFLVLPPLMEWIRVALAHAEHRRSFSVDSDDVRQAARLLLPGVDCEPRQLKTDDCFCVSR---------------------------------KLDAASTEAKFLQDLGFRMLNCGRTDLVNQAINLLGPGG-INSMSEQGMTPLMYACVRGDEAMVQMLLDAGADINSEVPNT-VQKFPSVFPETRQATPLTFAVLHQHIPVVQLLLDAGANVEGSLQDGMENYTETPLQLASAAGNFELVSLLLERGADPMIGTMYRNGISTA---PHGDMNSYSLAAAHGHRNVFCKLLSQSEKG-KADVLSLQEILAEGSDLEERNSLKMEAT-----------------RTGKAKLKALREAMYHSSEHGYVDITLDIRSLGVPWTLHTWLESLRTCFLQHRRPLIQGLLKEFSSIEEEEYTEELITHGLPLMFQILRASKNEVISQQLAVIFTQCYGPYPIPKLTEIKRKQ---TSRLDPHFLNNKEMSDVTFLVEGKPFYAHKVLLFTASNRFKLLLANRPAAEN--TCIEISHVKYNVFQLVMQYLYCGGTDALHIRNTEVMDLLSASKFFQLEALQRHCEIICAKNINTETCVEIYNHAKFLEAPELSAYIEGYFLKNMAVLIELEPFKQLLYNTPVENCCP----DVLHDLEKTLATRIRSIHLSSSKGSIV------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9PFY3-1", "uniprot_id": "M9PFY3_DROME", "id": "M9PFY3-1", "name": "BTB domain-containing protein", "aln": "MYCTKDCTCSLCRELRGYKPSDKKSAPSAPTLLSRMLNDNFILRRRGISLKNFQPQSLRNSEMLAQQMPVPRPPQTPSPTPIEELPDWATEDSSRAKKPNHKVVIYFGDSIHRGGQQSPLPSPKELHSQLLQEMSQKLKTSVAEEGLTGVEKVKKVQQMAGQPETSPPANDELPPYIESVQNGVINIRIEGNYRRASALVETVAKPTLAVVAPTKSECDCDAALGDNDDGNADDDSDDPGQDEAETDSCDWSYVQEWRRAAKRPTGNLPPNFVQHQAPSQVTGLPPVPPPQMQSPHQVQSQLPPSQTPLSSQKGLAVAMATPAPRVFKELAQQPNKGMPHKMVASSSSCSGGQANSSCKMPSPGTASKALIPQRAVAGPARLTVQSTPVKSQPPQLSGSLSQSQVSPNRPILGIPTTAANPTPPRIHQHDQFRALQRVQECHSSSDENRSSGHASMSDTGGHSSSPAGGMTLGPLPEDRLAAGVTNRSTRSRRHRGIMPGGKAPWSGTGLEDIKLAMLTLRSQTSSSTYSSLSAGSESSEPARRLGRYSSLETVVTSTSADEFVWVDSHNRLVELQHPPWSQQCILKVLRNGRCQQQA----EHLAVEAVSRLGYLLQRALVRIAREIQRFSAGVGLCSKQEVVGALRVVLSSSLADSCTKACLRSAAMFAVPGE--SALKQSKSARAGLQLSVGRFYRWMTDARLGKFIHEYAAVYLCAGIENLLEEIALQCNG-----------------------------------------------------------------------------------------------------TTAAALDQSIASSGDVWGLLQPFAHLNAGRIASGALALPRWANSLDQVIASS--------------GDFRGHLATCVGSIRELKEKALRTQQEFQLAAALSGSALAALFYFMRCSQLEHTELLAASGCHAGQAQSAAPGGGTSSAGHHVQELCYERAYVVLPPLAEWLRVAAAHAEHRNAMMIDKDDVMQAARLLLPGVDCPIRPVAHDEELPTKKTHFNTAPTVSSTGTGTGSSSCSSPVVSGIGIGIGEDTSELGRRATIGVAFKLLLTGRAELLAQAAQLLPPTTRYDTQNSAGLTALMIASIRNDEVALHALLDAGCDPNVEVPPAGSAGYPAIQPDTQHWTALSFAASRANYVALRILLERGGKVEGGARSSEEKCTLTPLQLAAGTGNLEIVALLLAHGANAFLSTQQKDSLCFAGSAQKGCFCAISVAAAHGHRSCLRKLLTHPVSPGTRDVLSLEEMLAEGDVGGVRGSGGPTGAGGPNSASASGNNEDILPLLNKTQIKRLQEAMYHSAENNHLDITIELRKLGVPWTLHCWMHALSAAHDLRLDAVIDQLLQDFLQVCPDDYSAQFVSECLPLLFNIFRN-KNEGTTLLLADIFATCFGWETLPPVKEQPPMQPVQGSRIDPKFVNNPELSDVTFRVEGKIFYGHKIVLVTASPRFQSMLSSKLSEGSSTPTVQINDIRYHIFQLVMQFLYCGGCSSLDVAHGDVLELMAAASFFQLEGLLRYTEARCSEMVDVDNVVAMYIHAKVYNANRLLEFCQCFLLQNMVALLTYDDSVKRLLFAKKIPNHD-----VLAGLLQTLQNRLKARKPNSGGGLVNSYRSPPVTPVKK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* .. *.:::*: :.. * . . . **. *:. : * : . ** *.:. : : :.. .:. . . : .. . : **: : * . . . . : :::*. *: *******:* **:* . *:* *: .*:.::** :: * *.* : ::: :. . : :.** *.** :***:.:***.*:*:. :**:**:** . :*.*:.:: : : :::::: ...:::*** *: ** .*: *.* *.** . : .. :. *** **** **.: . *: : :* . :.: ..* * : . .* . ....: * **.::***** **:*** **: **.:: :*.*** ************ * : *: : ..: *: : .:.*::* **::*: ** .** * :: .. *:*.** :.:*.**. :: *****.* * ** : .*:: *:*:: *.*:**. : : .:::**: .:***. . . *: : ******:..**:*:*:*** :**:.::.* ::.:. * : : * *******. : ***:: . . *:***:*:**** . .: .*:::: *:******:*:.::*:*:::*.:******* *:.:* .. : .:*: **::* : ::*: ::::. ***:*:*:: *** : *. **: *:* .:* :.* * **:**:*:** *:***** ***: **.**::*.*** **: :*:.: : . . ::*. ::* :******:** ** .:* : : ::::*::*:.****:.* *: * *:: : :. * :* **:. . .* : : ::*:** *: : : * ** .* :** *::: : .:. * : ", "identical_positions": 304, "similar_positions": 350, "identity": "18.14%" }, { "cls_id": "homologset.agr.RGD:1308649", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "B5DF91-1", "uniprot_id": "ELAV1_RAT", "id": "B5DF91-1", "name": "ELAV-like protein 1", "aln": "MSNGYEDHMAEDCRDDIGRTNLIVNYLPQNMTQEELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAISTLNGLRLQSKTIKVSYARPSSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAANPNQNKNMALLSQLYHSPARRFGGPVHHQAQRFRFSPMGVDHMSGISGVNVPGNASSGWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASLNGYRLGDKILQVSFKTNKSHK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70372-1", "uniprot_id": "ELAV1_MOUSE", "id": "P70372-1", "name": "ELAV-like protein 1", "aln": "MSNGYEDHMAEDCRDDIGRTNLIVNYLPQNMTQEELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAISTLNGLRLQSKTIKVSYARPSSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAANPNQNKNMALLSQLYHSPARRFGGPVHHQAQRFRFSPMGVDHMSGISGVNVPGNASSGWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASLNGYRLGDKILQVSFKTNKSHK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15717-1", "uniprot_id": "ELAV1_HUMAN", "id": "Q15717-1", "name": "ELAV-like protein 1", "aln": "MSNGYEDHMAEDCRGDIGRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAINTLNGLRLQSKTIKVSYARPSSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAANPNQNKNVALLSQLYHSPARRFGGPVHHQAQRFRFSPMGVDHMSGLSGVNVPGNASSGWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASLNGYRLGDKILQVSFKTNKSHK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**************.******************:********************************************.*****************************************************************************************************************:*************************************:***********************************************************************************************", "identical_positions": 321, "similar_positions": 5, "identity": "98.47%" }, { "cls_id": "homologset.agr.RGD:1308650", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZTD8-1", "uniprot_id": "SEM5A_RAT", "id": "D3ZTD8-1", "name": "Semaphorin-5A", "aln": "-------MKGACILAWLFSSLGVWRLARPETQDP--------AKCQRAEHPVVSYKEIGPWLREFRAENAVDFSRLTFDPGQKELVVGARNYLFRLQLEDLSLIQAVQWECDEATKKACYSKGKSKEECQNYIRVLLVGGD-RLFTCGTNAFTPVCTIRSLSNLTEIHDQISGMARCPYSPQHNSTALLTASGELYAATAMDFPGRDPAIYRS--LGTLPPLRTAQYNSKWLNEPNFVSSYDIGNFTYFFFRENAVEHD-CGKTVFSRAARVCKNDIGG-RFLLEDTWTTFMKARLNCSRPGEVPFYYNELQSTFFLPELDLIYGIFTTNVNSIAASAVCVFNLSAISQAFNGPFKYQENSRSAWLPY-PNPNPNFQCGTMDQGLYVNLTERNLQDAQKFILMHEVVQPVTTVPSFMEDNSRFSHVAVDVVQGRDTLVHIIYLATDYGTIKKVRAPLSQSSGSCLLEEIELFPERKSEPIRSLKILHSQSVLFVGLQEHVVKIPLKRCHFHQTRGACIGAQDPYCGWDAVMKKCTS-LEESLSMTQWDQS-VPTCPTRNLTVDGSFGPWSPWTPCTHTDGTAVGSCLCRSRSCDSPAPQCGGWQCEGPRMEITNCSRNGGWTPWTSWSPCSTTCGIGFQVRQRSCSNPTPRHGGRVCVGQNREERYCNEHLLCPPHVF------WTGWGPWERCTAQCGGGIQARRRTCEN------GPDCAGCNVEYQPCNTNACPELKKTTPWTPWTPVNISDNGG--HYEQRFRYTCKARLPDPNLLEVGRQRIEMRYCSSDGTSGCSTDGLSGDFLRAGRYSAHTVNGAWSAWTSWSQCSRDCSRGIRNRKRVCNNPEPKYGGMPCLGPSLEFQECNILPCPVDGVWSCWSSWSKCSATCGGGHYMRTRSCTNPAPAYGGDICLGLHTEEALCNTQTCP--ENWSEWSEWSVCDASGTQVRTRQCILLFPVGSQCSGNTTESRPCVFDSNFIPEVSVARSSSVEEKRCGEFN---MFHMMAVGLSSSILGCLLTLLVYTYCQRYQQQSHDATVIHP--VSPAALNSSITNHINKLDKYDSVEAIKAFNKNNLILEERNKYFN--PHLTGKTYSNAYFTDLNNYDEY------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62217-1", "uniprot_id": "SEM5A_MOUSE", "id": "Q62217-1", "name": "Semaphorin-5A", "aln": "-------MKGACILAWLFSSLGVWRLARPETQDP--------AKCQRAEHPVVSYKEIGPWLREFRAENAVDFSRLTFDPGQKELVVGARNYLFRLELEDLSLIQAVEWECDEATKKACYSKGKSKEECQNYIRVLLVGGD-RLFTCGTNAFTPVCTIRSLSNLTEIHDQISGMARCPYSPQHNSTALLTASGELYAATAMDFPGRDPAIYRS--LGTLPPLRTAQYNSKWLNEPNFVSSYDIGNFTYFFFRENAVEHD-CGKTVFSRPARVCKNDIGG-RFLLEDTWTTFMKARLNCSRPGEVPFYYNELQGTFFLPELDLIYGIFTTNVNSIASSAVCVFNLSAISQAFNGPFKYQENSRSAWLPY-PNPNPNFQCGTMDQGLYVNLTERNLQDAQKFILMHEVVQPVTTVPSFMEDNSRFSHLAVDVVQGRETLVHIIYLGTDYGTIKKVRAPLSQSSGSCLLEEIELFPERRSEPIRSLQILHSQSVLFVGLQEHVAKIPLKRCHFHQTRSACIGAQDPYCGWDAVMKKCTS-LEESLSMTQWDQS-IPTCPTRNLTVDGSFGPWSPWTPCTHTDGTAVGSCLCRSRSCDRPAPQCGGWQCEGPRMEITNCSRNGGWTPWTSWSPCSTTCGIGFQVRQRSCSNPTPRHGGRVCVGQNREERYCNEHLLCPPHVF------WTGWGPWERCTAQCGGGIQARRRTCEN------GPDCAGSNVEYHPCNTNACPELKKTTPWTPWTPVNISDNGG--HYEQRFRYTCKARLPDPNLLEVGRQRIEMRYCSSDGTSGCSTDGLSGDFLRAGRYSAHTVNGAWSAWTSWSQCSRDCSRGIRNRKRVCNNPEPKFGGMPCLGPSLEFQECNILPCPVDGVWSCWSSWSKCSATCGGGHYMRTRSCSNPAPAYGGDICLGLHTEEALCNTQTCP--ESWSEWSDWSVCDASGTQVRARQCILLFPVGSQCSGNTTESRPCVFDSNFIPEVSVARSSSVEEKRCGEFNMFHMFHMMAVGLSSSILGCLLTLLVYTYCQRYQQQSHDATVIHP--VSPAALNSSITNHINKLDKYDSVEAIKAFNKNNLILEERNKYFN--PHLTGKTYSNAYFTDLNNYDEY------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13591-1", "uniprot_id": "SEM5A_HUMAN", "id": "Q13591-1", "name": "Semaphorin-5A", "aln": "-------MKGTCVIAWLFSSLGLWRLAHPEAQGT--------TQCQRTEHPVISYKEIGPWLREFRAKNAVDFSQLTFDPGQKELVVGARNYLFRLQLEDLSLIQAVEWECDEATKKACYSKGKSKEECQNYIRVLLVGGD-RLFTCGTNAFTPVCTNRSLSNLTEIHDQISGMARCPYSPQHNSTALLTAGGELYAATAMDFPGRDPAIYRS--LGILPPLRTAQYNSKWLNEPNFVSSYDIGNFTYFFFRENAVEHD-CGKTVFSRAARVCKNDIGG-RFLLEDTWTTFMKARLNCSRPGEVPFYYNELQSTFFLPELDLIYGIFTTNVNSIAASAVCVFNLSAIAQAFSGPFKYQENSRSAWLPY-PNPNPHFQCGTVDQGLYVNLTERNLQDAQKFILMHEVVQPVTTVPSFMEDNSRFSHVAVDVVQGREALVHIIYLATDYGTIKKVRVPLNQTSSSCLLEEIELFPERRREPIRSLQILHSQSVLFVGLREHVVKIPLKRCQFYRTRSTCIGAQDPYCGWDVVMKKCTS-LEESLSMTQWEQS-ISACPTRNLTVDGHFGVWSPWTPCTHTDGSAVGSCLCRTRSCDSPAPQCGGWQCEGPGMEIANCSRNGGWTPWTSWSPCSTTCGIGFQVRQRSCSNPTPRHGGRVCVGQNREERYCNEHLLCPPHMF------WTGWGPWERCTAQCGGGIQARRRICEN------GPDCAGCNVEYQSCNTNPCPELKKTTPWTPWTPVNISDNGG--HYEQRFRYTCKARLADPNLLEVGRQRIEMRYCSSDGTSGCSTDGLSGDFLRAGRYSAHTVNGAWSAWTSWSQCSRDCSRGIRNRKRVCNNPEPKYGGMPCLGPSLEYQECNILPCPVDGVWSCWSPWTKCSATCGGGHYMRTRSCSNPAPAYGGDICLGLHTEEALCNTQPCP--ESWSEWSDWSECEASGVQVRARQCILLFPMGSQCSGNTTESRPCVFDSNFIPEVSVARSSSVEEKRCGEFN---MFHMIAVGLSSSILGCLLTLLVYTYCQRYQQQSHDATVIHP--VSPAPLNTSITNHINKLDKYDSVEAIKAFNKNNLILEERNKYFN--PHLTGKTYSNAYFTDLNNYDEY------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R9L1-1", "uniprot_id": "F1R9L1_DANRE", "id": "F1R9L1-1", "name": "", "aln": "-------MAEGRPLARGLVLLHSLLLLMPRGVPCRGAIRALESPCHRAEHPLISHTDIEPWIHRFRAEGTVDYSQLTFDPGQNELIVGARNHLFRLHLEDLSLIQEAEWHCDEFTKGACFSRGKSEEECQNYIRVLLVNGD-RLFTCGTNAFTPICTNRTLTNLTEVHDQISGMARCPYNPLHNSTALITSSGELYAATAMDFSGRDPAIYRS--LGGLPPLRTAQYNSKWLNEPNFVSSYDIGNFTYFFFRENAVEHD-CGRTVFSRAARVCKNDIGG-RFLLEDTWTTFMKARLNCSRPGEIPFNYNELQGTFFLPELELLYGIFTTNVNSIAASAVCAFNLSAITQVFSGPFKYQENSRSAWLPY-PNPNPDFQCGTIDFGSYVNLTERNLQDAQKFILMHEVVQPVVPVPYFMEDNVRFSHVAVDVVQGKDMLYHIIYLATDYGTIKKVLSPLNQTTGSCLLDEIELFPLKKRQPIRSLLILHSHSELFVGVREQVIKIPLMRCNFHKSREACVGARDPYCGWDLVLKKCTT-LEESVSMSQWEQS-ITRCPVRNVTVDGHYGAWSGWKTCSHSDGGSVGSCQCRTRACDSPSPQCGGQPCQGISVEVANCSRNGAWTPWTAWAPCSTSCGIGFQVRQRSCSNPTPRHGGRVCVGQNREERYCNEHLPCPPHVY------WSAWSPWERCTVPCGGGIQSRRRTCEN------GNECPGCSTEFQSCNTLPCPDLKKTTPWTPWTPVNISDNGG--HYEQRFRYTCKARVPEPGLLEVGRQRIEMRYCSSDGSTGCSTD---GDLLRSGRITGLTVNGGWSVWGPWSQCSRDCSSGVRNRKRTCSNPKPKYGGITCLGPAQEFQECNTTPCPVDGSWSCWSPWSKCSVTCGGGHYMRTRSCNNPPPAYGGDICLGLHTEEALCNIQPCP--ESWSDWSEWSPCDSSGSQVRLRHCDVLFPTGNQCSGNSSETRACLPISNFIPETSVARSS-QEERWCGDFN---VFHMIAVGLSSSILGCLVTLLVYTYCQRYQQQSHDATVIHP--ISAAPLNTSISNHINKLDKYDSVEAIKAFNKNNLILEERNKYFN--PQLAGKTYTNAYFTDVNTYDDF------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VTT0-1", "uniprot_id": "SEM5C_DROME", "id": "Q9VTT0-1", "name": "Semaphorin 5c", "aln": "MNMLILKLPKMFSQLWLLLILSLLTLEGPQPSTGSGYTTKSSVDLLENDSRYISYQDLMSTAKRFYDPETTWYSEMLFDVARNQVIVGARDTLYRMSFD-LEPLERASWGATPSEIAMCQAKGQSERWCRNYVRVLHSYGENQLYACGTNAFQPSCSWRQMENLTVTG-VDSGVVKCPFHPQANSTSLLQSNGQLFVGTATDFSGSDVAILRTGVESNKRFLRTKQYNNNWLSGAQFVGSFEAGHFVYFLLRESAAEHMSCGKVIYSRVARVCKNDVGGGGQLLRDNWTSFLKARLNCSLPGEYPYYFDEIQGMTYAESESILYATFRTSGSSIFGSAVCAYNLSSINAAFDGPFKQQEHSDAAWKTVNTNQRSQFQCGTSSIGHWL--------ESSRYQLMDEAVQPIGAEPLYHSKLEQFGRLALDIINTKTEQVHVLFVASSGNHIKKLSVKYDGDGVQTCLVELWQADDTGTSSLLNMAYLKVSDSLYLGTDLALTRIPAQHCSRHVSQSSCLNSMDPYCGWNELVERCMPQPQDSSVLQHWHQAPQITCPVLNAPIDGGWSTWSPWAVCQQHEQPDS-NCQCRQRSCNNPQPQHGGATCEGISTQVTNCTQHGGWTEWSAWSPCSQTCGIAVKIRRRTCGNPRPAFGGRTCVGSEQSEMYCRHLPPCPVAKPQSVDGGWGPWGEWSECSAQCGGGFRMRRRECNDPAPLNGGMECPGCRLDYEECNMQSCQEVRKLSAWTPWLTVTGSGNSSEPHMERRFRFVCRATSPDPSSVRIGLPKEESRNCHADGSCQRQVD----------------HDSADSDAADWSPCSVSCGGGVQQRHRGRGS-QSRVCNIHACPAEEQLSSNSLDNELEHGEWGCWSEWSACSVTCGLGLRRRTRRCLAG----HDRLCQGRALEEQKCEMVPCEDFLGWSAWSEWSSCSSDGIRLRHRRCLVEQPGSMECRGAEFEKTACVPNECEETQTASTATLPIVIFVG-------LLFTVACCLATYRFTKKRFMLSAEEALNKTTTTTASFDTYPNQYSSLPTKDYYDQRPKRQSSFRMPAKTSNLGNGNGTLNRNNMHQNNTPKVLAKTYIDCESGTIKRQSALNNCRSNIDDEKF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * * *. . : :*: :: . :.* :. :*.: ** .:::::****: *:*: :: *. :: ..* . * ::*:*:. *:**:*** *: :*::****** * *: * : *** **:.:**: * ***:*: :.*:*:..** **.* * ** *: . *** ***.:**. .:**.*:: *:*.**::**.*.** **:.::** *******:** **.*.**:*:******* *** *: ::*:*. : . .::*. * *. .** .****.:***:* .*.**** **:* :** . .* ...***** . * :: ::.:: **.*.***: . * : .. :*.::*:*::: : *::::.:. . ***: . . * *: ..: .: *: . *::* : :** :* : :: :*:.: ******: ::::* . ::* : :*.*: **. * .:** :. ** * * : : .* ** *:*: * ** ** *:* :::**:::*.** *::*:*** :***..::*:*:*.** * .***.***.::.* **.. ** * *. *..*:. ****:: *** *:: * :*.*. ::. ** .* :::* :.**** .*. *.*.. * *:***:.*:* .:*. :.:* : * * * :**: ..* :.. * ** ** .*. *:::*:* .. :.: .: . . : .. . .* *.*** *: **.*** * *** * . :* * ** *: .* .** **:** *.:.* ::* *:* : * . :* * *. .*: . .:.: : : ::. :* *:: : :* . . : : :* *. . : :: :: ..: . :.:.* *:..* : * *:: .*** :. :: . ", "identical_positions": 326, "similar_positions": 347, "identity": "28.8%" }, { "cls_id": "homologset.agr.RGD:1308651", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Y383-1", "uniprot_id": "LC7L2_HUMAN", "id": "Q9Y383-1", "name": "Putative RNA-binding protein Luc7-like 2", "aln": "-------MSAQAQMRAMLDQLMG-----TSRDGDTTRQRIKFSDDRVCKSHLLNCCPHDVLSGTRMDLGECLKVHDLALRADYEIASKEQDFF--FELDAMDHLQSFIADCDRRTEVAKKRLAETQEEISAEVAAKAERVHELNEEIGKLLAKVEQLGAEGNVEESQKVMDEVEKARAKKREAEEVYRNSMP-ASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIEIREKLEELKRVVAE-KQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRHRSRSMSRER---------KRRTRSK----SREKRHRHRSRSSSRSRSRSHQRS-RHSSRDRSRERSKR-RSSKERFRDQDLAS------CDRDRSSRDRSPRDRDRKDKKRSYESANGRSEDRRSSEEREAGEI-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7TNC4-1", "uniprot_id": "LC7L2_MOUSE", "id": "Q7TNC4-1", "name": "Putative RNA-binding protein Luc7-like 2", "aln": "-------MSAQAQMRAMLDQLMG-----TSRDGDTTRQRIKFSDDRVCKSHLLNCCPHDVLSGTRMDLGECLKVHDLALRADYEIASKEQDFF--FELDAMDHLQSFIADCDRRTEVSKKRLAETQEEISAEVAAKAERVHELNEEIGKLLAKVEQLGAEGNVEESQKVMDEVEKARAKKREAEEVYRNSMP-ASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIEIREKLEELKRVVAE-KQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRHRSRSMSRER---------KRRTRSK----SREKRHRHRSRSSSRSRSRSHQRS-RHSSRDRSRERSKR-RSSKERFRDQDLAS------RDRDRSSRDRSPRDRDRKDKKRSYESANGRSEDRRSSEEREAGEI-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8J8XLZ3-1", "uniprot_id": "A0A8J8XLZ3_RAT", "id": "A0A8J8XLZ3-1", "name": "RNA-binding protein Luc7-like", "aln": "-------MPAYFNLQGSFRKAP------HSPSRDTTRQRIKFSDDRVCKSHLLNCCPHDVLSGTRMDLGECLKVHDLALRADYEIASKEQDFF--FELDAMDHLQSFIADCDRRTEVSKKRLAETQEEISAEVAAKAERVHELNEEIGKLLAKVEQLGAEGNVEESQKVMDEVEKARAKKREAEEVYRNSMP-ASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIEIREKLEELKRVVAE-KQEKRNQERLKRREEREREEREKLR----------RSRSREHRRHRSRSMSRER---------KRRTRSK----SREKRHRHRSRSSSRSRSRSHQRS-RHSSRDRSRERSKR-RSSKERFRDQDLAS------RDRDRSSRDRSPRDRDRKDKKRSYESANGRSEDRRSSEEREAGEI-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VVI1-1", "uniprot_id": "LUC7L_DROME", "id": "Q9VVI1-1", "name": "Putative RNA-binding protein Alsin2", "aln": "MSAPSNKMSATDQMRAMLDQLMG-----TTRNGD--ERQLKFSDPRVCKSFLLDCCPHDILASTRMDLGECPKVHDLAFRADYESAAKTRDYY--YDIEAMEHLQAFIADCDRRTDSAKQRLKETQEELTAEVAEKANAVHGLAEEIGKKLAKAEALGEAGEVEDSMELMKEIEELRAKKIKAEHEYRTSMP-ASTYQQQKLRVCEVCSAYLGIHDNDIRLADHFGGKLHLGFLTIREKLIELEKTAAPRKAELKRTGKMTDREDEGRGRNRYFVGGRELDRRSRVHRSRSRERQRNRDGDRERPNNGRGPEEKGSERPKEAADGPERAERAPDRGGRRDDRDNHGRDHRERERDGRRDRDRHGRNDRGRFGDRGGGGGGGGHHRDDRRRSRSRERSPRERRNFNHFRDGGGGGNGQRKRSYSRERNYRR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q07508-1", "uniprot_id": "LUC7_YEAST", "id": "Q07508-1", "name": "Protein LUC7", "aln": "---MSTMSTPAAEQRKLVEQLMGRDFSFRHNRYSHQKRDLGLHDPKICKSYLVGECPYDLFQGTKQSLGKCPQMHLTKHKIQYEREVKQGKTFPEFEREYLAILSRFVNECNGQISVALQNLKHTAEER-MKIQQVTEELDVLDVRIGLMGQEIDSLIRADEVSMGMLQSVKLQELISKRKEVAKRVRNITENVGQSAQQKLQVCEVCGAYLSRLDTDRRLADHFLGKIHLGYVKMREDYDRLMKNNRTTNASKTATTLPGRRFV---------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. : : . : . .: : : * ::***.*:. **:*:: .*: .**:* ::* : :** * . : :: : : *. *: :*: : . : :.* .* ** :: :: :. * .** : : * .:*. . :::: :*: :. . *. .. ****:*****.***. *.* ****** **:***:: :**. .* : : . * ", "identical_positions": 59, "similar_positions": 81, "identity": "13.72%" }, { "cls_id": "homologset.agr.RGD:1308653", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4AE59-1", "uniprot_id": "STK11_RAT", "id": "D4AE59-1", "name": "Serine/threonine-protein kinase STK11", "aln": "MDVADPQPLGLFPEGELMSVGMDTFIHRIDSTEVIYQPRRKRAKLIGKYLMGDLLGEGSYGKVKEVLDSETLCRRAVKILKKKKLRRIPNGEANVKKEIQLLRRLRHRNVIQLVDVLYNEEKQKMYMVMEYCVCGMQEMLDSVPEKRFPVCQAHGYFRQLIDGLEYLHSQGIVHKDIKPGNLLLTTNGTLKISDLGVAEALHPFAVDDTCRTSQGSPAFQPPEIANGLDTFSGFKVDIWSAGVTLYNITTGLYPFEGDNIYKLFENIGRGDFTIPCDCAPPLSDLLRGMLEYEPAKRFSIRQIRQHSWFRKKHPLAEALVPIPPSPDTKDRWRSMTVVPYLEDLHGRAEEEEDEDLFDIEDGIIYTQDFTVPGQVLEEEVGQNGQSHSLPKAVCVNGTEP-QLSSKVKPEGRPGAANPARKVCS-SNKIRRLSACKQQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WTK7-1", "uniprot_id": "STK11_MOUSE", "id": "Q9WTK7-1", "name": "Serine/threonine-protein kinase STK11", "aln": "MDVADPEPLGLFSEGELMSVGMDTFIHRIDSTEVIYQPRRKRAKLIGKYLMGDLLGEGSYGKVKEVLDSETLCRRAVKILKKKKLRRIPNGEANVKKEIQLLRRLRHRNVIQLVDVLYNEEKQKMYMVMEYCVCGMQEMLDSVPEKRFPVCQAHGYFRQLIDGLEYLHSQGIVHKDIKPGNLLLTTNGTLKISDLGVAEALHPFAVDDTCRTSQGSPAFQPPEIANGLDTFSGFKVDIWSAGVTLYNITTGLYPFEGDNIYKLFENIGRGDFTIPCDCGPPLSDLLRGMLEYEPAKRFSIRQIRQHSWFRKKHPLAEALVPIPPSPDTKDRWRSMTVVPYLEDLHGRAEEEEEEDLFDIEDGIIYTQDFTVPGQVLEEEVGQNGQSHSLPKAVCVNGTEP-QLSSKVKPEGRPGTANPARKVCS-SNKIRRLSACKQQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15831-1", "uniprot_id": "STK11_HUMAN", "id": "Q15831-1", "name": "Serine/threonine-protein kinase STK11", "aln": "MEVVDPQQLGMFTEGELMSVGMDTFIHRIDSTEVIYQPRRKRAKLIGKYLMGDLLGEGSYGKVKEVLDSETLCRRAVKILKKKKLRRIPNGEANVKKEIQLLRRLRHKNVIQLVDVLYNEEKQKMYMVMEYCVCGMQEMLDSVPEKRFPVCQAHGYFCQLIDGLEYLHSQGIVHKDIKPGNLLLTTGGTLKISDLGVAEALHPFAADDTCRTSQGSPAFQPPEIANGLDTFSGFKVDIWSAGVTLYNITTGLYPFEGDNIYKLFENIGKGSYAIPGDCGPPLSDLLKGMLEYEPAKRFSIRQIRQHSWFRKKHPPAEAPVPIPPSPDTKDRWRSMTVVPYLEDLHG---ADEDEDLFDIEDDIIYTQDFTVPGQVPEEEASHNGQRRGLPKAVCMNGTEAAQLSTKSRAEGR--APNPARKACSASSKIRRLSACKQQ", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:*.**: **:*.**********************************************************************************************:************************************************* ****************************.******************.**************************************************************:*.::** **.*******:*************************** *** *************************** :*:********.************* ***..:*** :.******:****. ***:* :.*** :.*****.** *.***********", "identical_positions": 391, "similar_positions": 31, "identity": "89.27%" }, { "cls_id": "homologset.agr.RGD:1308654", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZSP7-1", "uniprot_id": "TTC3_RAT", "id": "D3ZSP7-1", "name": "E3 ubiquitin-protein ligase TTC3", "aln": "MPGHRGAPHLPPWVCGLCSMDDFAEGGLSLADDILLEDYPYEDDCICTPDFTTDDYVRVTQLYYEGVGMQYKDYAQSEKNLEYDICNIWCSKPLSILQDYCDAIKLYIFWPLLFQHQHSSIISRLHPCVEAIRSR--AAEISLKKLQHLELMEDIVDLAKK---VANDSFLIEGLLKIGYKIENKILAMEDALNWIKYTGDVTI---LPKLGSVDSGWPMLSIFFTEYKYHITRVVTENCNLLEEFRRHSCMQCVKQGELMKMRGNEEFAKEKFEIAVIYYTRAIEYRPENHLLYGNRALCFLRMGQFRNALSDGKRAIVLKNTWPKGHYRYCDALSMLGEYDWALQANIKAQKLCKNDPEGIKDLIQQHIKLQKQIEDLQGRTSNR-NPIKAFYESRAYIPRNSSAPAFRTSLNFVETERGFRKTKYRMANGGGHQNQKVADEALKGDDCDCHPEFLPPPSQPPRHKGKQKSRNNESEKPSSNSQVTLQVDLKSILEKQFSKSSRAAHQDFANIMKMLRSLIQDGYTALLEQRCRSAAQAFTELLNGLDPQKIKQLNLAMINYVLVVYGLAVSLLGIGRPEELSEAENQFKRIIEHYPNEGLDCLAYCGIGKVYLKKNRFLEALNHFEKAKTLICR--LPGILTWPTSNVIIEESKPEKVKVMLEKFVEECKFPPVPDAVCCYQKCRGFSKIQIYLTDPDFKGFIRISCCQYCKVEFHMNCWKKLKTTTFNDKIDKDFLQGICLTPDCEGIISKIIIFSSGGQVKCEFEHKVVKEKAPSRPVLKQKCSSLEKLRLKEDKKLKRKIQKQEAKKLAQERMEEDLRESNPPKPEEPEETVESAQSCQFLDDRILQCIKQNADKIKSVVLNTSTLLKELLSWKVLSTEDYTTCFSSKNFVHEAVDYVIGHLIQEKNRVKTRIFLHVLSELKELDPKLAPWIQRLNSFGLDATGPFFTRYGASLKELDFN--IVTFLWSEKYGHKLGSIEGKQ------LDYFCEPASVMEARCLIWLLEEHRDKFPALHSALDEFFDIMDSRCTVLRKQDSDEMPFGCIKVKNKGKKKKPKDSKPMLVGSGTASVTP---SSETVTP-EDHNRRNSDSAGPFAVPDHLRQDVEEFEALYDQHSSEYVVRNKKLWDINPKQKCSTLYDYFSQLLEEHGPLDMSDRMFSEEYEFFPEETRQILEKAGGLKSFLLGCPRFVVIDNCIALKKVASRLKKKRKKKNIKTKVEEISKTGEYLRVKLPLNPTAREFQPDVKSEAAA--------EDVTSIPGPADSSAPAAEDLKPQLDSDSSSGSASEDSRLEVVSPDLPTPLCEDAS------PSPTPAPEDAKPTYWTQSHLVTGFCTYLPFQGFGIAQSRPAYINMVPSLSQFTSIYTPLANISSEYPMPRSMPVVPSFVASERADGNAAAYFESHRLNTENASDDHTASETQILEGPLGMCVKSQSSTADARTALSEPEGNSRHSGSSDSLWEASLENVSGITDVPPAPSVAIQVSRSLIHQEVNTEPYAPFERQQGDLSQKEKECHLLREQLQVACEECEQMELRSSQETRDLEEKLQRHAEENKVSLPELQWALGKLDREIKKWHQEKKEIQERLKALKKKIKKVINTSDMSAQKNDGLDKECESQPDQSLGISSALTDEKAKVEESVRKGKELYEESQQRAVAAEVSVLENWKEREVCKLQGVATQAEACLKSLKLMNSDSAAYPDVECDILSWETFLSTVTEEIENTKCQFEEQIKAIKSGSRLSDLSSVQVSELLFPACSMIHPQLLSESSRHEDHGLVACVDSMTG---AVLNDPYVGPDSGCSEEVP-ELSLGSPTHHPEGAQQLEVKKASQVSPSEQNPEADEK---PSGQATRSSQSQKNPFNSIIEHLSVIFPCYASSELSGFIKKVRNKSKN-SFSGLSIEEIVERVTEHIVEEQK---KKKPNPGKDKKTSEAHPAASVSKSSPSPPLAAAGPSAKTKGQKKDDVP---APDGNSCQICHEIFKSKNMRVLKCGHKFHKGCFKQWLKGQSTCPTCGSSDLLSEE--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88196-1", "uniprot_id": "TTC3_MOUSE", "id": "O88196-1", "name": "E3 ubiquitin-protein ligase TTC3", "aln": "-------------------MDDFAEGGLSLADDILLEDYPYEDDCICTPDFTTDDYVRVTQLYYEGVGMQYKDYAQSEKNLEYDICNIWCSKPLSILQDYCDAIKLYIFWPLLFQHQHSSIISRLHPCVEAIRSR--AAEISLKKLQHLELMEDIVDLAKK---VANDSFLIEGLLKIGYKIENKILAMEDALNWIKYTGDVTI---LPKLGSVDNCWPMLSIFFTEYKYHITRVVTENCNLLEEFRRHSCMQCVKQGELMKMRGNEEFSKEKFEIAVIYYTRAIEYRPENHLLYGNRALCFLRMGQFRNALSDGKRAIVLKNTWPKGHYRYCDALCMLGEYDWALQANIKAQKLCKNDPEGIKDLIQQHVKLQKQIEDLQGRTSNK-NPIKAFYESRAYIPRNSSAPAFRTSLNFVETERGFRKTKYKMANGG-DQNQKVADEALKGDDCDCHPEFLPPPSQPPRHKGKQKSRNNESEKPSFNSEVSLQVDLKSILEKQFSKSSRAAHQDFANIMKMLRSLIQDGYTALLEQRCRSAAQAFTELLNGLDPQKIKQLNLAMINYVLVVYGLAVSLLGIGRPEELSEAENQFKRIIEHYPNEGLDCLAYCGIGKVYLKKNRFLEALNHFEKAKTLISR--LPGILTWPTSNVIIEESKPEKVKVMLEKFVEECKFPPVPDAVCCYQKCRGYSKIQIYLTDPDFKGFIRISCCQYCKVEFHMNCWKKLKTTTFNDKIDKDFLQGICLTPDCEGIISKIIIYSSGGQVKCEFEHKVIKEKVPSRPVLKQKCSSLEKLRLKEDKKLKRKIQKQEAKKLAQERMEEDLRESNPPKNEEPEETSDSAQRCQFLDDRILQCIKQNADKIKSVVLNTSTLLKELLSWKVLSTEDYTTCFSSKNFVHEAVDYVIGHLIQEKNRVKTRIFLHVLSELKELDPKLAPWIQRLNSFGLDAIGPFFTRYGASLKELDFH--VVTVLWDEKYGHKLGSIEGKQ------LDYFFEPASAMEARCLIWLLEEHRDKFPALHSALDEFFDIMDSRCTVLRKQDSDEMPFGCIKVKNKGKKKKPKDSKPMLVGSGAASVAP---SSEAVTP-EDHSRRNSDSAGPFAVPDHLRQDVEEFEALYDQHSSEYVVRNKKLWDINPKQKCSTLYDYFSQLLEEHGPLDMSDRMFSEEYEFFPEETRQILEKAGGLKSFLLGCPRFVVIDNCIALKKVASRLKKKRKKKNMKAKVEDISKTGEYLRVKLPLNPTAREFQPDVKSEALS--------EDVKSIPGPADSSTLAAEDLKAQLDSDSSSGSASEDSRLEVASPDSPTPLCEDAS------PSPTPAPEEAKPTYWAQSHLVTGFCTYLPFQGFGITQ-RPAYINMVPSLSQFTSIYTPLANISSEYPMQRSMPVVPSFVASNRADENAAAYFESPNLNTEHDSGDHMASETQILEDTLGVCVRSQGSAADADPALSEPEGNSEHSGSSDSLWEASLENVSGTTDAPAAPSVAIQVSRSMVHQEVNTEPYEPFETQQGDLSQKEKECHLLREQLKVACENCEQIELRSSQEIKDLEEKLQRHTEENKISKTELDWFLQDLDREIKKWQQEKKEIQERLKALKKKIKKVINTSEMSAQKNDGFDKECEPHPDQSLGFSSALTDEKTKAEESVRKGKELYEESHQRAVAAEVSVLENWKEREVCKLQGVASQSEAYLKSLKLMSSDSATYPDVEYDILSWESFLSTVREEIESKKSQFEEHIKAIKNGSRLSDLSSVQLSEVSFPGCSTIHPQFLSESSGHEDPGLVACVDSMTG---AVLNDPYMDSASGCPEEVP-ELSLGSPTHQPEVTQQLELKGASQVSPSEQSPEADEK---LSGQATRSSQSPKKPSNSIIEHLSVIFPCYTSTELAGFIKKVRNKTKN-SFSGLTIEEIVEKVTEHIVDEQK---KKKPNPGKDKKTSEAHSAASVAKSSQSPPLAAAGPSARTKGQKKDDVP---APDGNSCEICHEIFKSKNMRVLKCGHKFHKGCFKQWLKGQSTCPTCGSSDLLSEE--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P53804-1", "uniprot_id": "TTC3_HUMAN", "id": "P53804-1", "name": "E3 ubiquitin-protein ligase TTC3", "aln": "-------------------MDNFAEGDFTVADYALLEDCPHVDDCVFAAEFMSNDYVRVTQLYCDGVGVQYKDYIQSERNLEFDICSIWCSKPISVLQDYCDAIKINIFWPLLFQHQNSSVISRLHPCVDANNSR--ASEINLKKLQHLELMEDIVDLAKK---VANDSFLIGGLLRIGCKIENKILAMEEALNWIKYAGDVTI---LTKLGSIDNCWPMLSIFFTEYKYHITKIVMEDCNLLEELKTQSCMDCIEEGELMKMKGNEEFSKERFDIAIIYYTRAIEYRPENYLLYGNRALCFLRTGQFRNALGDGKRATILKNTWPKGHYRYCDALSMLGEYDWALQANIKAQKLCKNDPEGIKDLIQQHVKLQKQIEDLQGRTANK-DPIKAFYENRAYTPRSLSAPIFTTSLNFVEKERDFRKINHEMANGG-NQNLKVADEALKVDDCDCHPEFSPPSSQPPKHKGKQKSRNNESEKFSSSSPLTLPADLKNILEKQFSKSSRAAHQDFANIMKMLRSLIQDGYMALLEQRCRSAAQAFTELLNGLDPQKIKQLNLAMINYVLVVYGLAISLLGIGQPEELSEAENQFKRIIEHYPSEGLDCLAYCGIGKVYLKKNRFLEALNHFEKARTLIYR--LPGVLTWPTSNVIIEESQPQKIKMLLEKFVEECKFPPVPDAICCYQKCHGYSKIQIYITDPDFKGFIRISCCQYCKIEFHMNCWKKLKTTTFNDKIDKDFLQGICLTPDCEGVISKIIIFSSGGEVKCEFEHKVIKEKVPPRPILKQKCSSLEKLRLKEDKKLKRKIQKKEAKKLAQERMEEDLRESNPPKNEEQKETVDNVQRCQFLDDRILQCIKQYADKIKSGIQNTAMLLKELLSWKVLSTEDYTTCFSSRNFLNEAVDYVIRHLIQENNRVKTRIFLHVLSELKEVEPKLAAWIQKLNSFGLDATGTFFSRYGASLKLLDFS--IMTFLWNEKYGHKLDSIEGKQ------LDYFSEPASLKEARCLIWLLEEHRDKFPALHSALDEFFDIMDSRCTVLRKQDSGEAPFSSTKVKNKSKKKKPKDSKPMLVGSGTTSVTS---NNEIITSSEDHSNRNSDSAGPFAVPDHLRQDVEEFEALYDQHSNEYVVRNKKLWDMNPKQKCSTLYDYFSQFLEEHGPLDMSNKMFSAEYEFFPEETRQILEKAGGLKPFLLGCPRFVVIDNCIALKKVASRLKKKRKKKNIKTKVEEISKAGEYVRVKLQLNPAAREFKPDVKSKPVSDSSSAPAFENVKPKPVSANSPKPACEDVKAKPVSDNSSRQVSEDGQPKGVSSNSPKPGSEDANYKRVSCNSPKPVLEDVKPTYWAQSHLVTGYCTYLPFQRFDITQTPPAYINVLPGLPQYTSIYTPLASLSPEYQLPRSVPVVPSFVANDRADKNAAAYFEGHHLNAENVAGHQIASETQILEGSLGISVKSHCSTGDAHTVLSESNRNDEHCGNSNNKCEVIPESTSAVTNIPHVQMVAIQVSWNIIHQEVNTEPYNPFEERQGEISRIEKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEENKISKTELDWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGKEKEHELHLDQSLEISNTLTNEKMKIEEYIKKGKEDYEESHQRAVAAEVSVLENWKESEVYKLQIMESQAEAFLKKLGLISRDPAAYPDMESDIRSWELFLSNVTKEIEKAKSQFEEQIKAIKNGSRLSELSKVQISELSFPACNTVHPELLPESSGDDGQGLVTSASDVTGNHAALHRDPSVFSAGDSPGEAPSALLPGPPPGQPEATQLTGPKRAGQAALSERSPVADRKQPVPPGRAARSSQSPKKPFNSIIEHLSVVFPCYNSTELAGFIKKVRSKNKN-SLSGLSIDEIVQRVTEHILDEQK---KKKPNPGKDKRTYEPSSATPVTRSSQGSPSVVVAPSPKTKGQKAEDVPVRIALGASSCEICHEVFKSKNVRVLKCGHKYHKGCFKQWLKGQSACPACQGRDLLTEESPSGRGWPSQNQELPSCSSR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3BCR2-1", "uniprot_id": "A0A8M3BCR2_DANRE", "id": "A0A8M3BCR2-1", "name": "RING-type E3 ubiquitin transferase", "aln": "---------------------------MSDSDDSDLEEG---------PNVQRHKTKIVYHAQFPYIHMEPPDIVYER----------WCKMKLKRKQDLGHLMHVSVFWWHILLRQQENHPTTAWAVKMGFLDSNVSNDLSLKRLEKMEILESILATMERGLSLRDVENKARAVVSLSQRFFQEEDCLTEAIRWLLDSGDPDLGQKLMDLGSVEVRYLTLSFVFMEYARYIQVVSCSKKKALMEMKFEPDSWSLSKSDEMKNKGNEHFQKKKYDVALKWYSKAIKYHPNNHILYGNRALCLLRSGKYLKALGDGKRAIVLQPDWAKGHYRFCDALFYLGEHQRALLANQQAQDACRADVEGQKDLLQQHERFQSELQEARDMKTKKPDPKKVSSKARSHTAGASSAAHLKTSAPPETPPEPQTKKSEKQKQQADTSGPSGARAHTDGG-----ADRLRDVSSESSPRKAKKASSSTAEKPAVRSKLPAAADRASAPAEVVS---------AAAVRERFCAAVLEAHVALSDQRCHNAQQSFSVALAILESSSTTELGLTELDKSVLLYGYATALLETGQPEELAEAEKLFAKLESTER--KFQSLVHYGMGRVYLKENRFAKARECFSNALLMIQRHITPGKLTWPTTKAIVEETQPAWLQEHLESLVEVCRFPPKADAVCRHQQCVSHS-VQIYFSDPDFKGFIQLVCCQSCRIEFHMSCWRKLKTLSFADKNDKDFLKDSCFTPDCAGQICHILIFGSTGLIKCEFKSSIPKARAAGRSRLRQQCTSIKKLMSKNDRKLRRKQQRLAARSSHQEKREVMREEAAKEQPADRASPRD-----CIYMDRVLQQIHDNKALFKEEPVSISCFWEHLRPWLDLFESKGQESVLNSRRGVGVLSELVDLLLESRNRVWARVFIQTLGSTLHIKPRLQHWAQQLDDTGLKAAQSFINRYRSHLEDLELKPLLSFPPLQESLVEKLGSVTELFDRDDFTVMEYLRQAPAKEMRLFIWTLESSRERYQSCHTILDQYFED-DAVCLVIKKTDDDEHMSSVFKSKNRHRKKKHKELKSVIVLSGMRAGHSRDEDDEDELFSEEDSLMFLNDMDPFSVPDHLRYQLAEFEENYSGSAQRSYYER--MLDNHPDPTKETLYDYFAQVLEEHGPLCATDPLLVGELQNFPLEAQQQIADAGGLQAFLLQSLRFTMTERLIGLMKHAVCLSESSN------------------THSQILNPSASEFWP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSGEPPSSTGEPALLLPDPYTDEEDQLSAAEMTESDTEETRAEKHT----AVRAQDFQDRTDVSVNTEPCAPFENNSGELMGLQKRRLYLLEELQRIRADGEAEQQRRQEELTELQEDTHNISQRMQIASTELSMFQQKLEEEVKKDQQEKKENQETLRSLKMEIKELVELQESLSRDISVRNRQYEAELELFLDVSNQCAAERLSLEDEIKRFRDACVKAERRSASAQLCVLQSRREHALRRLRMTVSEGKMVVKHLSDVALS-SPSAALLSAIEDWKRHVSEAEGRIHATEEECEAQMQAVQQGSRLCSLPDISTPSVPSAPALPALQTPVSSAAPEE-----------------------------------------------------------------------------SSSRRSAAPQHLSVYERIVERLHIMFPHYDRLVLNKFLQEVRSSCSGGVLSSLTYNEVINRVAQLILDHQENICQQMNITAGDAADLSCPPSDCTLRAAGTPPLTHVWKNVPEKHRNSALVLN----MEDPCIICHEDMSAEDLCVLECRHSFHRECIKSWLKEQSTCPTCREHALLPEDFPLLPGRQRRTHTAS-----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: :* **: .:. .. * : : :: * .. **. :. ** . ::: :** :: :*:.. : . . . : ::.**:*:::*::*.*: :: : : . .:: :. :: :: .: :*:.*: :** : * .***:: : **:.* ** :* : .. : * *:: .. .:.:.: ** :***.* *:::::*: :*::**:*:*:*::********:** *:: :**.***** :*: *.*****:**** ***:: ** ** :**. *: * ** ***:*** ::*.:::: :. .::: :* *. : *:: . **. : ** . * . . : . .. . * . . .: *. . : :*: .. :** : * :. .* . : .* * : : : : : :.: ** :***:.* *:*: * *:... .:*.*: :: :::** * :** *:****:***: * :: . ::.*.: *:*:****:*** :* : *.:* :* * ** *****::.*:**::* :: **.:** *:*** .**:* :*:* ..* :***::********:: *** *::****.**:**** :* ** *****:. *:**** * *.:*:*:.* * :****: .: * :.. *. *:*:*:*::** *:*:**:** *: *:. **: * .*: : : .. : : **:** *:: :*. . : : :.* .* * .. .. . . .:. :: *::..*** :*:*::.*.. .:.*:* * *:*:. **.* .*:.** : *: *:: : .*. .**.*: : : . *. * * :** **. *::: : *: **::*: *: * *::* *..* . * **: :*** *: *.::* ** : . ..* *:.. :. .**:****** :: *** *. :.. .. : * :*. . .******:*.******* :: :: * : ** *::* : .****:.*** . **.: :. *.* * * *.:. : . ***:* ** * :. .. *:.:. *.:. :... .: . * *.. . .. * * . . .***** *** ..*:: :*. * ::*: : * : : :* :*:*. :. :. ::: .**. .*:.*:** :***** ** *::** :**:: : .: ::. . ::: * . : * .*. : *: . *: ::: :: ::.:*:.:*::.**:. :* : :*: ::.: :* * : . :. . : * .*: .:* . .*. : : * :::*::.****..*..:. ..: . . :..:: .: .. :: . . : *:*:* ::** * * *:::**.. .. :*.*: :*::::*:: *::.*: :: .. * . .: . ::: .* . . . * :: * ..* **** :.:::: **:* *.:*: *:*.*** **:**:* **.*: ", "identical_positions": 473, "similar_positions": 616, "identity": "22.84%" }, { "cls_id": "homologset.agr.RGD:1308655", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Y4Y9-1", "uniprot_id": "LSM5_HUMAN", "id": "Q9Y4Y9-1", "name": "U6 snRNA-associated Sm-like protein LSm5", "aln": "MAAN-ATTNPSQLLPLELVDKCIGSRIHIVMKSDKEIVGTLLGFDDFVNMVLEDVTEF-EITPEGRR----ITKLDQILLNGNNITMLVPGGEGPEV---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62322-1", "uniprot_id": "LSM5_MOUSE", "id": "P62322-1", "name": "U6 snRNA-associated Sm-like protein LSm5", "aln": "MAAN-ATTNPSQLLPLELVDKCIGSRIHIVMKSDKEIVGTLLGFDDFVNMVLEDVTEF-EITPEGRR----ITKLDQILLNGNNITMLVPGGEGPEV---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZBJ0-1", "uniprot_id": "D3ZBJ0_RAT", "id": "D3ZBJ0-1", "name": "U6 snRNA-associated Sm-like protein LSm5", "aln": "MAAN-ATTNPSQLLPLELVDKCIGSRIHIVMKSDKEIVGTLLGFDDFVSILFISVCLFSEITPEGRR----ITKLDQILLNGNNITMLVPGGEGPEV---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VRT7-1", "uniprot_id": "Q9VRT7_DROME", "id": "Q9VRT7-1", "name": "U6 snRNA-associated Sm-like protein LSm5", "aln": "MTAVPPPSNISTLMPLELVDKCIGSRIHIIMKNDKEMVGTLLGFDDFVNMLLDDVTEY-ENTPDGRR----ITKLDQILLNGNNITMLVPGGELAE----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40089-1", "uniprot_id": "LSM5_YEAST", "id": "P40089-1", "name": "LSM complex subunit LSM5", "aln": "-------MSLPEILPLEVIDKTINQKVLIVLQSNREFEGTLVGFDDFVNVILEDAVEWLIDPEDESRNEKVMQHHGRMLLSGNNIAILVPGGKKTPTEAL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . ::***::** *..:: *:::.::*: ***:******.::: .. : . : * : : .::**.****::*****: . ", "identical_positions": 29, "similar_positions": 37, "identity": "29.0%" }, { "cls_id": "homologset.agr.RGD:1308657", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q96FV9-1", "uniprot_id": "THOC1_HUMAN", "id": "Q96FV9-1", "name": "THO complex subunit 1", "aln": "--------MSPTPPLFSLPEARTRFTKSTREALNNKNIKPLLSTFSQVPG-SENEKKCTLDQAFRGILEEEIINHSS-CENVLAIISLAIGGVTEGICTASTPFVLLGDVLDCLPLDQCDTIFTFVEKNVATWKSNTFYSAGKNYLLRMCNDLLRRLSKSQNTVFCGRIQLFLARLFPLSEKSGLNLQSQFNLENVTVFNTNEQESTLGQKHTEDREEGMDVEEGEMGDEEAPTTCSIPIDYNLYRKFWSLQDYFRNPVQCYEKISWKTFLKYSEEVLAVFKSYKLDDTQASRKKMEE-----------------LKTG-GEHVYFAKFLTSEKLMDLQLSDSNFRRHILLQYLILFQYLKGQVKFKSSNYVLTDEQSLWIEDTTKSVYQLLSENPPDGERFSKMVEHILNTEENWNSWKNEGCPSFVKERT-----SDTKPTRIIRKRTAPEDFLGKGP-TKKILMGNEELTRLWNLCPDNMEACKSETREHMPTLEEFFEEAIEQADPENMVENEYKAVNNSNYGWRALRLLARRSPHFFQPTNQQFKSLPEYLENMVIKLAKELPP-----------------------------PSEEIKTGEDED----EEDNDALLKENESPDVRRDKPVTGEQIEVFANKLGEQWKILAPYLEMKDSEIRQIECDSEDMKMRAKQLLVAWQDQEGVHATPENLINALNKSGLSDLAESLTNDNETNS----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8R3N6-1", "uniprot_id": "THOC1_MOUSE", "id": "Q8R3N6-1", "name": "THO complex subunit 1", "aln": "--------MSPTPALFSLPEARTRFTKSTREALNNKNIKPLLTAFSQLPG-SENEKKCTLDQAFRGVLEEEIINHSA-CENVLAIISLAIGGVTESVCTASTPFVLLGDVLDCLPLDQCDTIFTFVEKNVATWKSNTFYSAGKNYLLRMCNDLLRRLSKSQNTVFCGRIQLFLARLFPLSEKSGLNLQSQFNLENVTVFNTNEQESTLGQKHTEDREEGMDVEEGEMGDDEAPTTCSIPIDYNLYRKFWSLQDYFRNPVQCYEKISWKTFLKYSEEVLAVFKSYKLDDTQASRKKMEE-----------------LKTG-GEHVYFAKFLTSEKLMDLQLSDSNFRRHILLQYLILFQYLKGQVKFKSSNYVLTDEQSLWIEDTTKSVYQLLSENPPDGERFSKMVEHILNTEENWNSWKNEGCPSFVKERA-----SDTKPTRVVRKRAAPEDFLGKGP-NKKILIGNEELTRLWNLCPDNMEACKSETREYMPTLEEFFEEAIEQADPENMVESEYKAVNNSNYGWRALRLLARRSPHFFQPTNQQFKSLPEYLENMVIKLAKELPP-----------------------------PSEEIKTGEDED----EEDNDALLKENESPDVRRDKPITGEQIESFANKLGEQWKILAPYLEIKDSDIRQIECDSEDMKMRAKQLLVAWQDQEGVHATTDNLISALNKSGLSDLAESLTNDTETNS----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P59924-1", "uniprot_id": "THOC1_RAT", "id": "P59924-1", "name": "THO complex subunit 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------MEYYSAIKN------NDIMKFLSKWMG----------VEEIIPKAGKEPDVLQQTMDTENVVYLHNG-----------------------------------LLLSYN---------------------------------------------------------------------------------DFMKFIG---------------KWMELEYIILS--------------------------------------------------------------------EFCEERA-----SYTKLKRGVWKRSAPEDFLDKRP-NKKILIGNEELTRLWNLCPDNMEACKLETREYMPILEEFFEEAIEQADAENMVESEYKAINNSNYGWSTLRFLAWRSPHFFQPTNQQFKNMTEYLENMVIKLAKELPP-----------------------------HSEEIKTGEDED----EEDNDALLKENESPDVRQDKPITGERIESLTNKLDEQWKILAPYLEIKDSDIRQIECYSEDMKKRAKQLLVAWKDQEGVHETTDNLIGALNKSGLSDLAESLTNDTETNSYLLSLLFY--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7SYB2-1", "uniprot_id": "THOC1_DANRE", "id": "Q7SYB2-1", "name": "THO complex subunit 1", "aln": "---------MSPPSHFDFIEARDKFTVATKNAVDTRNCKPLTTAFSHLPG-NETEKKATLDQALRGVLEEQIVNQKVNVDDFLSLIYISIDGVTEGICSATTPFLLLGDVLDCLPLDQCDKIFSFVEENVSTWKSNTFYSAGKNYLLRMCNDLLRRLSKSQNTVFCGRIQLFLARLFPLSEKSGLNLQSQFNLDNITVFNKNEQDSTLGQQHTEVKEEGMDVEEGEMGDEDAPAPSSIPIDYNLYRKFWTLQDYFRNPVQCYDKFSWMTFIKYSDEALAVFKSFKLDDMQASKKKLEE-----------------MRTSSGDHVYFAKFLTSEKLMDLQLSDSNFRRHILLQYLILFQYLKGQVKFKSSSCVLNDDQSLWIEDTTKLVYQLLKEIPPDGDKFGSMVEHILNTEENWNSWKNEGCPSFVKERP-----AETKPIRPSRKRQAPEDFLGKGP-DRKILMGNDELTRLWNLNPDNMEACKSENREFMPSLEDFFEEAIEQADPANMVEDEYKVVRNSNYGWRALRLLSRRSPHFFQPTNQQFKSLADYLENMVIKLAKELPKD---------------------------IPSEEIKTGEEDD----DENGDNLLKDSNDSPSIQSKAVTNSQMDEIAAKLGSQWKTLADHLEMSDKEIRVIESDSEDVDLQAKMLLVAWQDREGSQATMESLVTALNAAGFNNIADNLS---ET------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VNI8-1", "uniprot_id": "Q9VNI8_DROME", "id": "Q9VNI8-1", "name": "", "aln": "MSTAVEVANTAPEKLANYFALQSAFEKALELAITDGKVELLVKEYNRFPANTEHDKRLPMDHAFRVLLMKRLDEDVS---RIGELVRLSVEATRAEIVSNTIPVVLLIDTFDVVTLDKCQKIFQFVEDMVEVWKEEIFFSSCKNNILRMCNDLLRRLSRTQNTVFCGRIQLFLSKFFPFSERSGLNIVSEFNLDNFTEYGLDSKDHD---------------ESDNKELEDTAEDIPLKIDYDLYCKFWSLQDFFRNPNQCYNKPQWKMFQMHADNILQSFSSFKLEDVRQSSNENASGTDQAMDVDEEAVDTTAVSSVIKANHFFAKFLTNPKLLALQLSDANFRRAVLVQFLILFQYLQVSVKFKSDTQTLTADQADFIKETESRVYKLLEETPPYGKRFSRTVYHMLAREEMWNNWKNEGCKEFKKPEEPTLSEEDSKPTPNKRPRRPLGDALRDASRSGKFYLGNDNLTRLWNYSPDNLQACKSEQRNFLPLLETYLETPHEKVDP--------------AFEWRALRLLARQTPHFFTSLSQPSSKISDYLEQVRKRLIRDKEPKPAALLSNNSSENNFGLSVNNVHTEGEQDATVALQDGEPEQDLEVEDNEPVVEEVDEVPAHEKPLMVTKEHIEEVAPLIGEPWMKVGKKIGFTNDELLFFQMEHPTANVACVKMLTNWISDDD-DATLENWAYMLEGLEMNKAAEAVKAIIEREKSGSTAAFCLR", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::*: ** **::: **: . : .::* : :. : . :: :*.. . : :.*: * **: : : ::::** .* : . :* * . * * . . *: :**::****** ***::*** * *:.:* ** ::* . *:.*. : * :**:*: ::**** . .* ..:.:***:: :* :: : :: ** :: ::: : : .: . : :* .::: .: :.. * :. : :.:.:: :: . . :*. * . :. . * :. *: :.. *: :. * ", "identical_positions": 66, "similar_positions": 126, "identity": "8.99%" }, { "cls_id": "homologset.agr.RGD:1308658", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P39105-1", "uniprot_id": "PLB1_YEAST", "id": "P39105-1", "name": "Lysophospholipase 1", "aln": "-----------------------------------------------------MKLQSLLVSAAVLTSLTENVNAWSPN-NSYVPANVTCD-DDINLVREASGLSDNETEWLKKRDAYTKEALHSFLNRATSN---FSDTS-LLSTLFGS---------------------------NSSNMPKIAVACSGGGYRAMLSGAGMLAAMDNRTDGANEHGLGGLLQGATYLAG-----LSGGNWLTSTLAWNNWTSVQAIVDNTTESN------------------------------SIWDISHSILTPDGINIFKTGSRWDDISDDVQDKKDAGFNISLADVWG--RALAYNFWPSLHR-GGVGYTWSTLR-EADVFKNGEMPFPITVADGRYPGTTVINLNATLFEFNPFEMGSWDPTLNAFTDVKYLGTNVTNGKPVNKGQCIAGFDNTG---------------FITATSSTLFN-----QFLLRLNSTDLPSFIANLATDFLEDLSDNSDDIAIYAPNPFKEANFLQKNATSSIIES-------EYLFLVDGGEDNQNIPLVPLLQKERELDVIFALDNSADTDDYWPDGASLVNTYQRQFGSQGLNLSFPYVPDVNTFVNLGLNKKPTFFGCDARNLTDLEYIPPLIVYIPNSRHSFNGNQSTFK---MSYSDSERLGMIKNGFEAATMGNFTDDSDFLGCVGCAIIRRKQQNLN--ATLPSECSQCFTNYCWNGTID------SRS---VSG------------------------------VGNDDYSSSASLSASAAAASASAS--------ASASASASASGSSTHKKNAGNALVNYSNLNTNTFIGVLSVISAVFGLI---------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q03674-1", "uniprot_id": "PLB2_YEAST", "id": "Q03674-1", "name": "Lysophospholipase 2", "aln": "-----------------------------------------------------MQLRNILQASSLISGLSLAADSSSTTGDGYAPSIIPCPSDDTSLVRNASGLSTAETDWLKKRDAYTKEALHSFLSRATSN---FSDTS-LLSTLFSS---------------------------NSSNVPKIGIACSGGGYRAMLGGAGMIAAMDNRTDGANEHGLGGLLQSSTYLSG-----LSGGNWLTGTLAWNNWTSVQEIVDHMSESD------------------------------SIWNITKSIVNPGGSNLTYTIERWESIVQEVQAKSDAGFNISLSDLWA--RALSYNFFPSLPD-AGSALTWSSLR-DVDVFKNGEMPLPITVADGRYPGTTVINLNATLFEFTPFEMGSWDPSLNAFTDVKYLGTNVTNGKPVNKDQCVSGYDNAG---------------FVIATSASLFN-----EFSLEASTSTYYKMINSFANKYVNNLSQDDDDIAIYAANPFKDTEFVDRNYTSSIVDA-------DDLFLVDGGEDGQNLPLVPLIKKERDLDVVFALDISDNTDESWPSGVCMTNTYERQYSKQGKGMAFPYVPDVNTFLNLGLTNKPTFFGCDAKNLTDLEYIPPLVVYIPNTKHSFNGNQSTLK---MNYNVTERLGMIRNGFEAATMGNFTDDSNFLGCIGCAIIRRKQESLN--ATLPPECTKCFADYCWNGTLS------TSANPELSGNSTYQSGAIASAISEATDGIPITALLGSSTSGNTTSNSTTSTSSNVTSNSNSSSNTTLNSNSSSSSISSSTARSSSSTANKANAAA-ISYANTNTLMSLLGAITALFGLI---------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q08108-1", "uniprot_id": "PLB3_YEAST", "id": "Q08108-1", "name": "Lysophospholipase 3", "aln": "-------------------------------------------------MIRPLCSKIIISYIFAISQFLLAANAWSPT-DSYVPGTVSCP-DDINLVREATSISQNESAWLEKRNKVTSVALKDFLTRATAN---FSDSSEVLSKLFNDG--------------------------NSENLPKIAVAVSGGGYRSMLTGAGVLAAMDNRTEGAYEHGLGGLLQSTTYLSG-----ASGGNWLVGTLALNNWTSVQDILNNMQNDD------------------------------SIWDLSDSIVTPGGINIFKTAKRWDHISNAVESKQNADYNTSLADIWG--RALAYNFFPSLNR-GGIGLTWSSIR-DFPVFQNAEMPFPISVADGRYPGTKVINLNATVFEFNPFEMGSWDPSLNSFANVKYLGTNVSNGVPLERGKCTAGFDNAG---------------FIMGTSSTLFN-----QFLLRINSTHLPSFITRLARHFLKDLSQDFNDIAVYSPNPFKDTKFLDSDYTTSIVDS-------DSLFLVDGGEDDENVPVLPLIQKERDVDIIFAVDNSADMRLAWPDGSSLVHTYERQFVKQGQGMSFPYVPDTNTFVNLGLNKKPTFFGCDANNLTDLQYIPPLVVYLPNAEYSFNSNQSAFK---LSYSESQRRSMIQNGFEIATRNNFTDDPEFMGCVGCAIIRRKQQALN--ITLPPECETCFKNYCWNGTLD------TTPLPDVEKDVHHSFINVN--------------------SFNSSIGQEESLYAGSSASQSSSS-----SSSSSSSSEIPSATATLEKKAATNSGSHLSGISVKFSAMIMLTLLMFTGAV---------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "A0ACD6B737-1", "uniprot_id": "A0ACD6B737_DANRE", "id": "A0ACD6B737-1", "name": "Phospholipase A2", "aln": "-------------------------------------------------MLKKEAKPYWNLSVKVLRAKIHQSYDYLNESDCYVILNLPTASARTKRTKTIP--SNNNPEWNETFTFRVFSNIKNVLEIMVYDEDPFMRDDQCGTILFDVNNLTPGKKETKCFIINEKTKNELWVEFEMTKSSVTPRPCTSNGVLVAGPFCELNVEIDKLLKNSEAMQNMVLKLKGAYKEDIVISNLDESSSIMTTLRYFINRDLETELNLTSEAAVRPENTVVVDGTVPALVDAELTSVPLKPLPAKQKLTVSLPLGEN-KVDLQLKTDDRSDEEMDVRLDFDIPEKEKRFLAKRRKVVSQALQKALN-LSSAPDPSKVP-LVAVVCSGGGSRALTSTYGSLKGLQNIQILDTVSYITGVSGATWALAS-IYEEPNWSKGDIDKTMESVKKELSKTIFSLFSSEQLQRYKEKIDEREKQGHIVSLID-----MWGLALEYLFRGKKHMGTLSELQRTVSEGQNPLPIFTSVNIKNGRAECIEDAEWCEFTPYEVGFPKYGAFIPAQNFGSEYYLGHMIKKLPETALSILVGMWSSIFSVNLTNIWSIATGAAPSWTP-QVEGGKSNTETS-KPTALTTHLINPVTDFAKMLCGFMTSRPIVSQMYNFLRGFNLHRNYQENTGFIAWKEKHPDAFPNTMTPSDPVLSLVDAGFALNAGFPPVVRSHRNVD--VILSINYSWELDQFKVVKQAQEYCTDRKIPFPKIDFKKLESEPLREVYVFEDKNNPDAPIVLHFPLVNVSFKQFKAPGVKREGEKELKEGAVDVDFNSNTSPYATHKLTYTPEDFQRLINLTSYNIQNNKDVILNALNKALNRNRDKRTGEESKKEEKGKTCSAPTPQPGSQKTQKTQK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9Q6G1-1", "uniprot_id": "A0A8M9Q6G1_DANRE", "id": "A0A8M9Q6G1-1", "name": "Phospholipase A2", "aln": "MFFSSFLESSVPTGLSCRNFRHMHDIMNKTTYVSCTVLRLHCRPAEEKTMLKIELMPYWNLSVTVLRGTFSQSYDVLSKNDCYVTLKLPTASACCHRTKTVK--NSNEPKWNETFHFRVHSGIKNILEFHMFDADKLTKDDHLSTILFDISNLTPGQKQTKCFMSDDERRGALWVEFEMTVSSEKPIPYFSNGVLMAGPFCALDVKLQKHLKTN-AENKMMLRLRGAYKEDCMILSSDENSSCLQNTCFYINRDLETEFSLLPPKAGAEMDEKYAN------TADILSSVPMKPLSAKQQMKLSMPIAQG-EVHLELNTEDCLDEEMDVRLEFDIPVEEKNFLLKRRKVVSQALQKALN-LGSAPDPSKVP-LVAVVCSGGGTRAMTATFGGLRALQTLQLLDAVSYITGVSGSTWTMAS-LYSDANWSNSDLNVAMESVKKEISKSVFSVFSPEQLQHYKEKMEEREKQGHLVSLID-----MWGLAIEYLIHGKKKLGTLSDQQMALCNGQNPLPIYTALNMKNGKTGCIIETEWCEFTPYEVGFTKYGAFIPAQNYGSEYYLGHMVKKLPEAGIYSLLGIWSSVFSLSLTQLWTVVTGVIPSWAS-KVGEEVNHTDTDNKPSTSNTLHVNPMTELAKKLSNFLTSRPIISQVFNFLRGFQLHRNYTENCDFTAWKDTHPDAFPNSLTPADATLGLVDSAFVLKSGFPPVLRSNRLAD--VILSLNYAWDSDHFKILKETQEYCREHKTLFPKIDFKKLETEPIREVYVFEDEENPEVPIVLHFPLINVSFKQFKAPGKRREGKVEMKEGDFDVDFTRMFCPFSTLNLTYEPENFQKLSSLTAYNILNNKDVILNALKKALKRNKEK--------------------NPITTNVSKF--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P0C871-1", "uniprot_id": "PA24B_MOUSE", "id": "P0C871-1", "name": "Cytosolic phospholipase A2 beta", "aln": "--------------------------------------------------MQAKVPETCLLTVRVLRASGLPSKDLVTSSDCYVTLNLPTASSHTLQTRTVK--NSRNPVWNQNFHFRIHRQLKNVMELKVFDHDLVTRDDPVLSVLFDVGTLQIGTQR-QSFSLGTQEKGCLEVEFRLQTLTDCEEQLISNGIVVARELSCLHVELKRTGDPKRSERKVQLVVAGACEG------PQDASAGTGSFHFHYPACWEQELNVHLQDDPHEQ-----------------LKVPLRTLPSSQLVRLVFPTSQEPLMRLELKKEEGP-KELAVRLGCGPCPEEQAFLSKRKQVVAAALKKALQ-LDQDLHEDEIP-VIAVMATGGGIRAMTSLYGQLAGLQELGLLDCISYITGASGSTWALAN-LYEDPEWSQKDLAGPTEVLKTQVTKSKLGALAPSQLWRYRQELAERARLGHPTCFTN-----LWALINEALLHDKPHEHKLSDQREALSRGQNPLPIYCALNSKEQGLSTFDFGEWCEFSPYEVGFPKYGAFISSELFGSEFFMGRLVKQLPESRICFLEGIWSNLFAASLQDSLYWSSEPSQFWDR-WAQDQAN-LDKEQVPHLKIAEPPTMAGRIAELFTDLLTKRPLAHATHNFTRGLHFHKDYFQNSHFSAWKASKLDRLPNQLTPTEPHLCLLDVGYLINTSCPPLLQPTRDVD--LILSLDYNLYG-AFQQLQLLSRFCQEQGIPFPSISPSPEEQRQPQECHLFCDPAQPEAPAVLHFPLVNDSFQDYSAPGVPRTSE-EKAAG--EVNLSSSDSPYHYTKVTYSQEDVDKLLRLTHYNICNNQDRLREAMHQAVQRRRKR--------------------KQFRPE------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A1I6-1", "uniprot_id": "D4A1I6_RAT", "id": "D4A1I6-1", "name": "Phospholipase A2", "aln": "-----------------------------------------MALQTCPVYMQAKVPETHLLTVRVLQASGLPSKDLVTSSDCYVTLNLPTASSGTLQTRTVK--NSRNPVWNQNFHFRIHRQLKNVMELKVFDQDLMTKDDPVLSVLFDVGTLQVGTQR-QSFSLSAQEDGRLEVEFRLQTLTDCEEQLISNGILVAQELSCLHVELKRTGDPKRSERKVQLVVAAACEG------PQEAPVGTGSFRFHYPACWEQELSVHLQDDPHEQ-----------------LKVPLRTLPSSQLVRLVFPTSQEPLMRLELKKEDGP-KELAVRLGCGPCPEEQAFLSKRKQVVAAALKKALQ-LDQDLQEDEIP-VIAVMATGGGIRAMTSLYGQLAGLKELGLLDCISYITGASGSTWALAN-LYEDPEWSQKDLAGPTEMLKTQVTKSKLGALAPSQLWRYRQELAERARLGYPTCFTN-----LWALINEALLHDKPHEHKLSDQREALSRGQNPLPIYCALNSKEKGLSTFEFGEWCEFSPYEVGFPKYGAFIPSELFGSEFFMGRLVKQLPESRICFLEGIWSNLFAASLQDSFYWSSEPSQFWDR-WAQDQAN-LDKEQVSHLKIAEPPTAAGKIAELFTDLLTKRPLAQATHNFMRGLHFHKDYFHHPHFSTWKASKLDKFPNQLTPAEPHLCLLDVGYFINTSCPPLLQPTRDVD--LILSLDYNLSG-AFQQLQLVSRFCQEQGIPFPSISPSPEEQRQPQECHMFCDPAQPEAPAVLHFPLVNDSFRDHSAPGVPRTSE-EKTAG--EVNLSSSNSPYDYTKVTYSQEDVDKLLRLTHYNICNNQDRLREAMHQAVQRRRNR--------------------RQFRRE------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0C869-1", "uniprot_id": "PA24B_HUMAN", "id": "P0C869-1", "name": "Cytosolic phospholipase A2 beta", "aln": "-------------------------------------------------MAVAEVSRTCLLTVRVLQAHRLPSKDLVTPSDCYVTLWLPTACSHRLQTRTVK--NSSSPVWNQSFHFRIHRQLKNVMELKVFDQDLVTGDDPVLSVLFDAGTLRAGEFRRESFSLSPQGEGRLEVEFRLQSLADRGEWLVSNGVLVARELSCLHVQLEETGDQKSSEHRVQLVVPGSCEG------PQEASVGTGTFRFHCPACWEQELSIRLQDAPEEQ-----------------LKAPLSALPSGQVVRLVFPTSQEPLMRVELKKEAGL-RELAVRLGFGPCAEEQAFLSRRKQVVAAALRQALQ-LDGDLQEDEIP-VVAIMATGGGIRAMTSLYGQLAGLKELGLLDCVSYITGASGSTWALAN-LYEDPEWSQKDLAGPTELLKTQVTKNKLGVLAPSQLQRYRQELAERARLGYPSCFTN-----LWALINEALLHDEPHDHKLSDQREALSHGQNPLPIYCALNTKGQSLTTFEFGEWCEFSPYEVGFPKYGAFIPSELFGSEFFMGQLMKRLPESRICFLEGIWSNLYAANLQDSLYWASEPSQFWDR-WVRNQAN-LDKEQVPLLKIEEPPSTAGRIAEFFTDLLTWRPLAQATHNFLRGLHFHKDYFQHPHFSTWKATTLDGLPNQLTPSEPHLCLLDVGYLINTSCLPLLQPTRDVD--LILSLDYNLHG-AFQQLQLLGRFCQEQGIPFPPISPSPEEQLQPRECHTFSDPTCPGAPAVLHFPLVSDSFREYSAPGVRRTPE-EAAAG--EVNLSSSDSPYHYTKVTYSQEDVDKLLHLTHYNVCNNQEQLLEALRQAVQRRRQR--------------------RPH---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P53541-1", "uniprot_id": "SPO1_YEAST", "id": "P53541-1", "name": "Putative meiotic phospholipase SPO1", "aln": "--------------------------------------------------MQKLLFVFSVLLTVVLATAPFQVQCPSSPLIREAKHELCPEETLYLKKKKIKTKNKLIQFLKSLTEAKFSSKFYKRVLKDPPKIGIAISGGGYRSMLVGTGFISQMN------DYGLFEYSDYIAGLSGGSWILMDLVVQNFEVKSLLQEWDLEEDLLLGIPEFDISEEEIVTNAKKEYNDNDLKMKKRQGGSLITSSSNFYEQIEEIMNSIEEIPEDYMITKRNLN-----------PLARLKKIFFPNNTFTGTDAKIETFKKVLDFYKSLHLKIKPKKMEGFQISFTDYWG--KAIVQRLKKNFDDDPNHSFSFSKLVNSSKKFKECSVPIPIFVANCKNG-----LLSNVIFEFTPFEFGSWENILRLFVKLPYLGSKIVSG---KAEKCINNFDDLG---------------FITATSSSIFNNVLIFIWNLASQSSREAMKALNMVMGIFGLGKEEIFSISKDSSRLETDYAVYQPNPFYLYPEKDNVLTNKNHLYLVDGGEDGENIPLRTLVIPERELDVIFVLDSSSDIDN-YPNGSKLKRIFEKLDEEN-VHYQFPN--------NVKTFTHPIVIGCNATKRTGHDSFLPIIIYHANANHGNASNTSTFK---ITYNQSEVSSMLPTGRGVFSN---DYDLYYKNCLGCILTKRTMDRLPRKKKFSPFCLQCFKDYCYS------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : : . . : . : . . : *.. . : : : . . : .. . . : : . . : : . . . : . .: : : :. . .:* : . : .: : . . : : : * . :. . . . :: . ..: : :: : : . . * . *: * . : . . : . : . * : . : :. : ", "identical_positions": 7, "similar_positions": 91, "identity": "0.78%" }, { "cls_id": "homologset.agr.RGD:1308659", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "B5DFK6-1", "uniprot_id": "B5DFK6_RAT", "id": "B5DFK6-1", "name": "AP-3 complex subunit delta-1", "aln": "--------MALKMVKG-SIDRMFDKNLQDLVRGIRNH---KEDEAKYISQCIDEIKQELKQDNIAVKANAVCKLTYLQMLGYDISWAAFNIIEVMSASKFTFKRVGYLAASQCFHEGTDVIMLTTNQIRKDLSSPSQ---YDTGVALTGLSCFVTPDLARDLANDIMTLMSHTKPYIRKKAVLIMYKVFLKYPESLRPAFPRLKEKLEDPDPGVQSAAVNVICELARRNPKNYLSLAPLFFKLMTSSTNNWVLIKIIKLFGALTPLEPRLGKKLIEPLTNLIHSTSAMSLLYECVNTVIAVLISLSSGMPNHSASIQLCVQKLRILIEDSDQNLKYLGLLAMSKILKTHPKSVQSHKDLILQCLDDKDESIRLRALDLLYGMVSKKNLMEIVKKLMTHVDKAEG---------------------TTYRDELLTKIIDICSQSNYQHITNFEWYISILVELTRLEG----TRHGHLIAAQMLDVAIRVKAIRKFAVSQMSSLLDSAHLVASSTQRNGICEVLYAAAWICGEFSEHLQGPQQTLEAMLRPKVTTLPGHIQAVYVQNVVKLYASILQQKEQAADTEGAQEVTQLLVERLPQFVQSADLEVQERASCILQLVKHVQKLQAK------------------GVPVAEEVSALFAG-ELNPVAPKAQKKVPVPEGLDLDAWINEPP-----SDSESEDEKPKAIFHEEEP------RHTRRRQPEEDEEELARRREARKQEQANNPFYIKSSPSPQ--KRYQDAPGVEHIPVVQIDLSVP----LKVPGMPMSDQYVKLEEQRRHRQRLEKDKKRKKKE----KGKRRHSSLPTESDEDIAPAQRVDIITEEMPENALPSDEDDKD----PNDPYRALDIDLD--------KPLADSEKLPVQKHRNAETVKSPEKEG-----VPGVEKKSKKPKKKEKKPKERERE--KKDKKGE-------------------------------------DLDFWLSTTPPPAAAPVPAPSTEGLAASIVTPPKGECEVLKGEEPQDEEDHMDHDQERKSSRHKKKKHRKEKE--ERPRDKKKAKRKQVVQLEN-GAPAEEEEEE-EEPIPPMSSYCLLAENPYIKVT-------YDVQASLQKDSQVTVSIILENQSSSFLKNMELNVLDSLNTKMARPEGSSVHDGVPVPFQLPPGVSNEAQFVFTIQSIVMAQKLKGTLSFIAKDDEGATHEKLDFRLHFSCSSYLITTPCYSDAFAKLLESGDLSMNSIKVDGISISFQNLLAKICFYHHFSVVERVDSCASMYSRSIQGHHVCLLVKKGESSVSVDGKCSDATLLSSLLEEMKTTLSQC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54774-1", "uniprot_id": "AP3D1_MOUSE", "id": "O54774-1", "name": "AP-3 complex subunit delta-1", "aln": "--------MALKMVKG-SIDRMFDKNLQDLVRGIRNH---KEDEAKYISQCIDEIKQELKQDNIAVKANAVCKLTYLQMLGYDISWAAFNIIEVMSASKFTFKRVGYLAASQCFHEGTDVIMLTTNQIRKDLSSPSQ---YDTGVALTGLSCFVTPDLARDLANDIMTLMSHTKPYIRKKAVLIMYKVFLKYPESLRPAFPRLKEKLEDPDPGVQSAAVNVICELARRNPKNYLSLAPLFFKLMTSSTNNWVLIKIIKLFGALTPLEPRLGKKLIEPLTNLIHSTSAMSLLYECVNTVIAVLISLSSGMPNHSASIQLCVQKLRILIEDSDQNLKYLGLLAMSKILKTHPKSVQSHKDLILQCLDDKDESIRLRALDLLYGMVSKKNLMEIVKKLMTHVDKAEG---------------------TTYRDELLTKIIDICSQSNYQHITNFEWYISILVELTRLEG----TRHGHLIAAQMLDVAIRVKAIRKFAVSQMSSLLDSAHLVASSTQRNGICEVLYAAAWICGEFSEHLQGPQQTLEAMLRPKVTTLPGHIQAVYVQNVVKLYASILQQKEQAADTEAAQEVTQLLVERLPQFVQSADLEVQERASCILQLVKHVQKLQAK------------------GVPVAEEVSALFAG-ELNPVAPKAQKKVPVPEGLDLDAWINEPP-----SDSESEDEKPKAIFHEEEP------RHTRRRQPEEDEEELARRREARKQEQANNPFYIKSSPSPQ--KRYQDAPGVEHIPVVQIDLSVP----LKVPGMPMSDQYVKLEEQRRHRQRLEKDKKRKKKE----KGKRRHSSLPTESDEDIAPAQRVDIITEEMPENALPSDEDDKD----PNDPYRALDIDLD--------KPLADSEKLPVQKHRNAEAVKSPEKEG-----VLGVEKKSKKPKKKEKKTKERERE--KKDKKGE-------------------------------------DLDFWLSTTPPPAAAPIPAPSTEELAASTITSPKDECEVLKGEE----EDHVDHDQERKSSRHKKKKHRKEKEKEERPRDKKKAKKKQVAPLEN-GAAAEEE----EEPIPPMSSYCLLAESPYIKVT-------YDIQASLQKDSQVTVSIILENQSSSFLKNMELNVLDSLNTKMTRPEGSSVHDGVPVPFQLPPGVSNEAQFVFTIQSIVMAQKLKGTLSFIAKDDEGATHEKLDFRLHFSCSSYLITTPCYSDAFAKLLESGDLSMNSIKVDGISMSFQNLLAKICFYHHFSVVERVDSCASMYSRSIQGHHVCLLVKKGESSVSVDGKCSDATLLSSLLEEMKTTLAQC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14617-1", "uniprot_id": "AP3D1_HUMAN", "id": "O14617-1", "name": "AP-3 complex subunit delta-1", "aln": "--------MALKMVKG-SIDRMFDKNLQDLVRGIRNH---KEDEAKYISQCIDEIKQELKQDNIAVKANAVCKLTYLQMLGYDISWAAFNIIEVMSASKFTFKRIGYLAASQSFHEGTDVIMLTTNQIRKDLSSPSQ---YDTGVALTGLSCFVTPDLARDLANDIMTLMSHTKPYIRKKAVLIMYKVFLKYPESLRPAFPRLKEKLEDPDPGVQSAAVNVICELARRNPKNYLSLAPLFFKLMTSSTNNWVLIKIIKLFGALTPLEPRLGKKLIEPLTNLIHSTSAMSLLYECVNTVIAVLISLSSGMPNHSASIQLCVQKLRILIEDSDQNLKYLGLLAMSKILKTHPKSVQSHKDLILQCLDDKDESIRLRALDLLYGMVSKKNLMEIVKKLMTHVDKAEG---------------------TTYRDELLTKIIDICSQSNYQYITNFEWYISILVELTRLEG----TRHGHLIAAQMLDVAIRVKAIRKFAVSQMSALLDSAHLLASSTQRNGICEVLYAAAWICGEFSEHLQEPHHTLEAMLRPRVTTLPGHIQAVYVQNVVKLYASILQQKEQAGEAEGAQAVTQLMVDRLPQFVQSADLEVQERASCILQLVKHIQKLQAK------------------DVPVAEEVSALFAG-ELNPVAPKAQKKVPVPEGLDLDAWINEPL-----SDSESEDERPRAVFHEEEQ------RRPKHRPSEADEEELARRREARKQEQANNPFYIKSSPSPQ--KRYQDTPGVEHIPVVQIDLSVP----LKVPGLPMSDQYVKLEEERRHRQKLEKDKRRKKRKEKEKKGKRRHSSLPTESDEDIAPAQQVDIVTEEMPENALPSDEDDKD----PNDPYRALDIDLD--------KPLADSEKLPIQKHRNTETSKSPEKD------VPMVEKKSKKPKKKEKKHKEKERD--KEKKK--------------------------------------------------------------------------------------------EKEKKKSPKPKKKKHRKEKE--ERTKGKKKSKKQPPGSEEAAGEPVQNGAPE-EEQLPPESSYSLLAENSYVKMT-------CDIRGSLQEDSQVTVAIVLENRSSSILKGMELSVLDSLNARMARPQGSSVHDGVPVPFQLPPGVSNEAQYVFTIQSIVMAQKLKGTLSFIAKNDEGATHEKLDFRLHFSCSSYLITTPCYSDAFAKLLESGDLSMSSIKVDGIRMSFQNLLAKICFHHHFSVVERVDSCASMYSRSIQGHHVCLLVKKGENSVSVDGKCSDSTLLSNLLEEMKATLAKC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AM99-1", "uniprot_id": "A0A8M3AM99_DANRE", "id": "A0A8M3AM99-1", "name": "AP-3 complex subunit delta-1", "aln": "--------MALKIVKG-SIDRMFDKNLQDLVRGIRNH---KEDEAKYISTCIDEIKQELKQDNIAVKANAVCKLTYLQMLGYDVSWAAFNIVEVMSSSKFTYKRIGYLAASQCFHEGTDVIMLTTNQIRKDLSSPNQ---YDTGVALTGLSCFVTPDLARDLANDIMTLMSHTKPYIRKKAVLIMYKVFLKYPESLRPAFPRLKEKLEDPDPGVQSAAVNVICELARRNPKNYLSLAPLFFKLMTSSTNNWVLIKIIKLFGALTPLEPRLGKKLIEPLTNLIHSTSAMSLLYECVNTVIAVLISLSSGMPNHSASIQLCVQKLRILIEDSDQNLKYLGLLAMSKILKTHPKSVQSHKDLILQCLDDKDESIRLRALDLLYGMVSKKNLMEIVKKLMLHVDKAEG---------------------TTYRDELLTKIIDICSQSNYQYITNFEWYISILVELTRLEG----TRHGHLIASQMLDVAIRVKAIRAFAVAQMATLLDNAHLLTGNTQRNGICEVLYAAAWICGEFAEHLEDPMLTLEAMLRPKVATLPGHIQAVYVQNAAKLFATVLQKHEGETDSQAAQETSQLLIDRLPLFVQSANLEVQERASCILQLVKYIQKLQQK------------------NVEVAEEVTALFAG-ELNPVAPKAQKKVPIPEGLDLDAWINEPP-----SESESEDEKPKAVFAKEEP------KHSRSRHTEVDEKELARRREARKQEQANNPFYIKASPSSQ--KVY-DAPGVEHIPVVQIDLSVP----LKVPGMPMSDQYVKLEEERRQKEKADKKKKEKKKK-REKRGKGRKGDSGPESEEDITPAHHVDIVTEEMPENALPSDDDDKD----PNDPHKALDIDLDNLLSGAGSRPLADSEKLPVRTHR-PEVLKSPAEDRDDNTIPQETKKKSSKDKKEKKKDKEKDRKRSKEDKKKKKKHKDVEEELPESLPEEVVQSEETKEVAVPPTSADASDLDFWLSSAPVPPVAQVVTVSSSAAAATVDSSSAAAAESEPEE------LKDTEPDDTKSSKHKKKKQKKEKEEKEKKKKKRHHHHHHHHSDAGAEDSVQNGTVEDEEPLPPMSNYSLLAENSYIKMMKEDADQVCDIQGNHQDESKVVVSVIFENKSDSFLKSMEFNVLDSLNSKLQRPDGAGPHDGLTVPFQLPPGVSNEARFVFSVQSIVMPQKLKGTLTFIVKTDESSTHEKLDFKLHFTCTSYLITTPCYSDAYAKLLESGDLKGSSLRLEGVNMPFHHLLARICFHHHFSVVERIDSCASMYSRSIQGHHVCLLVKSSDQTVSIDAKCDEPSLLGNVLDEIKQTFSKC", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P54362-1", "uniprot_id": "AP3D_DROME", "id": "P54362-1", "name": "AP-3 complex subunit delta", "aln": "--------MALKKVKGNFFERMFDKNLTDLVRGIRNN---KDNEAKYISTCIEEIKQELRQDNISVKCNAVAKLTYIQMLGYDISWAGFNIIEVMSSSRFTCKRIGYLAASQCFHPDSELLMLTTNMIRKDLNSQNQ---YDAGVALSGLSCFISPDLSRDLANDIMTLMSSTKPYLRMKAVLMMYKVFLRYPEALRPAFPKLKEKLEDPDPGVQSAAVNVICELARKNPKNYLPLAPIFFKLMTTSTNNWMLIKIIKLFGALTPLEPRLGKKLIEPLTNLIHSTSAMSLLYECINTVIAVLISISSGMPNHSASIQLCVQKLRILIEDSDQNLKYLGLLAMSKILKTHPKSVQAHKDLILACLDDKDESIRLRALDLLYGMVSKKNLMEIVKRLLGHMERAEG---------------------SAYRDELLYKVIEICAQSSYLYVTNFEWYLTVLVELIQLEAG---SRHGRLIAEQLLDVAIRVPVVRQFAVNEMTNLLD---TFTVSAQSNSMYEVLYAAAWIVGEFAGELEDAEKTLNILLRPRL--LPGHIQGVYVQNVIKLFARLATTCLELQDLPGLVTLCDHVLDKLQHFNGSSDIEVQERANSACMLIEMLRNQLSTSTDAMAMDTTTEGGIPPLAIEIVQEMTLLFTG-ELIPVAPKAQRKVPLPDGLDLDEWINAPPPEDAASSSSSEHDKDELFVSATQAGTGADGGEKRRQSLELTPEQLERQRMARLIEQSNNPHYLKSTPTASGASNADQYDNIDDIPITELPLDMEGVAALRVGITKRSDKYLQEQQAAQGSKDGKKKHKKGKKS---KKAKNKVAYNSSSESEGEPKPLHIVNTTLDMPEGVSMSDSEDKDGKYDPNDPHRALDIELD----------ITEFEAPAVRSASKKSAADKENLKT-----PADLAGGGNAAKKDRKKDKDKDKE-----------------------------------------------------------------------------------------------------------RKVKREHR------ESKRERKEAAVQPVIDLIDADTPTPSP--------------SHISAT---------------------SNNNNTSTVLPDAPKHHKKKKNKEKTTDEAPDALATATGSSIID-----------VGGEE--ASEVASKVHKKKHK--------KEKSQRKEKK--------------KASESASVSAIVSIGDYEQP----LGISTPSKEIL--------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08951-1", "uniprot_id": "AP3D_YEAST", "id": "Q08951-1", "name": "AP-3 complex subunit delta", "aln": "MTSLYAPGAEDIRQRLRPFGFFFEKSLKDLIKGIRSHNETPEKLDQFFKQVLSECREEVNSPDLNSKTNAVLKLTYLEMYGFDMAWCNFHILEVMSSNKLQQKRVGYLAASQSFYKDSDILMLATNLLKKDLKYDGNNDVVKVGIALSGLSTIITPSLARDIADDLFTMLNSTRPYIRKKAITALFKVFLQYPEALRDNFDKFVSKLDDDDISVVSAAVSVICELSKKNPQPFIQLSPLLYEILVTIDNNWIIIRLLKLFTNLSQVEPKLRAKLLPKILELMESTVATSVIYESVNCIVKGNMLEED----DFETAMACLERLHTFCDSQDPNLRYISCILFYKIGKINTDFISRFDQLIIRLLSDVDVSIRSKAIELVEGIVDEDNLKAIVQTLMKQFVDEDVVILQTGSIVYEKSKRIPIIIPENYKIKMVNVIISICSADNYSSVNDFEWYNAVIMDLAMLCQDISDKSLGSKIGEQFRNLMIKVPSMREVTIANIIKLIS------NDNINKQLPTVLRECIWCLGEFSTLVENGN-DLIKIMTENISYYSHSVQEVLILALVKVFSNWCNN-FQEDKRFEIKMVLKELIEFFENLSYSSTFEVQERSVEVLEFLRLSLEALEEDTEG-------------LPMLLSEVLPSFFNAYELAPIARGTQLKLAVDENLDLETPFLTKEA----ADELLDEQKSDAISDLMSD-----ISMDEQVELKFVDDSDTSYEEKEKLDDFENPFEIEREKERMSNPYYLGEEDEERT--------------------KNSKDLLDLNEEESSDKKPETIRLNRTDN-----SLNSLSLSTTEISRKKKKGKKKNRVQVLSDEPVIEAAPKRKDAFQKPHDNHSTQNPLKK--------------DKINLRMHSQLENFDFSNFGQ------SSNAGRGSQEEGNLRKEDELELS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RLEANLIVKDEKDNLSDTEEVIVIKKKKKGKKSKSKN----------------------------------------------------------------KLKTKAKNSPEPNEFLRDQSTDI------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :*:*.* **::***.: :. :::. :.* ::*:.. :: * *** ****::* *:*::*. *:*:****:.:: **:*******.*: .::::**:** ::***. .: ..*:**:*** :::*.*:**:*:*::*::. *:**:* **: ::****:***:** * :: .**:* * .* ****.*****:::**: :: *:*::::::.: ***::*:::*** *: :**:* **: : :*:.** * *::**.:* :: : .. . : *:::*: : :..* **:*:. : : ** * :.. :. ..:**: *.* * *** :*::*: *:*.:.** **: *: :. : *: ::: :*.**: ..* :.:**** :::::* * . * *. *: :: *:* :* .:: :: *:. . : : ** . * ***: :: * :: .: . :* * : *::: . . ::: : : *: :*****: ::. : : : : :. :* . ** *:* :* *:.: :.***: : :.. :.:: . . . : .. . . :: :**. :: . : *.. :. :: : .. : . . . . . .. .. : * . : . ** *:* : : : . : :: . . .. : . :* .: : . . :: . . . : . .. .. * :: . . ", "identical_positions": 193, "similar_positions": 313, "identity": "14.29%" }, { "cls_id": "homologset.agr.RGD:1308660", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AWV3-1", "uniprot_id": "A0A8I6AWV3_RAT", "id": "A0A8I6AWV3-1", "name": "Glycine cleavage system P protein", "aln": "MQLCARAWGLRLGPGAGGGHRLARGTGLSWAPRSRDSSSGGGGGGG-DRGAAGASRLLERLLPRHDDFARRHIGPGDKDRREMLQALGLASIDELIEKTVPASIRLKRPLKLEDP---VCENEILETLHAIASKNQ-IWRSYIGMGYYNCSVPQTILRNLLENSGWVTQYTPYQPEVSQGRLESLLNYQTMVSDITGLDMANASLLDEATAAAEAMQLCHRHNKRK--RFFIDPRCHPQTIAVVQTRAKYRGVIVELKLPHEMD-----FSGKDVSGVLFQYPDTEG---KVEDFTELVERAHQTGSLTCCATDLLALCILRPPGEFGVDIALGNSQRFGVPLGYGGPHAAFFAVRESLVRMMPGRMVGVTRDATGKEVYRLALQTREQHIRRDKATSNICTAQALLANMAAMFAIYHGSHGLQHIAKRVHNATLILSEGLKR--AGHQLQHDLFFDTLKVQCG--CSLKEVLGRAAQRQ-INFRLFDDGTLGISLDETVTEKDLDDLLWIFGCESSTELVAEGMGEEWRGLLGSSFKRTSPFLTHQVFNSYHSETNLVRYMKKLENKDISLVHSMIPL------------VAPITWREFANIHPFVPLDQAQGYQQLFQELEKDLCELTGYDRVSFQPNSGAQGEYAGLATIRAYLDQKGERHRTVCLIPKSAHGTNPASAYMAGMKIQPVEVDRYGNIDVAHLKAMVDKHKENLAAIMITYPSTNGVFEENISDVCALIHQHGGQVYLDGANMNAQVGICRPGDFGSDVSHLNLHKTFCIPHGGGGPGMGPIGVKKHLVPFLPSHPIVCLKPNED-TWPVGTVSAAPWGSSSILPISWAYIKMMGGKGLKEATEIAILNANYMAKRLERYYRVLFRGARG---YVAHEFILDTRPFKKSANIEAVDVAKRLQDYGFHAPTMSWPVAGTLMIEPTESEDKAELDRFCDAMISIRQEIADIEEGRIDPRVNPLKMSPHSLT-CVTSSRWD-RPYSREVAAFPLPFVKPENKFWPTIARIDDIYGDQHLVCTCPPMEVYESPFSEQKRASS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91W43-1", "uniprot_id": "GCSP_MOUSE", "id": "Q91W43-1", "name": "Glycine dehydrogenase (decarboxylating), mitochondrial", "aln": "MQLCARAWGLRLGRGAGGGHRLARGTGLSWAQRSRDSSGGGGGGGGGDRGAAGASRLLERLLPRHDDFSRRHIGPGDKDRREMLQALGLASIDELIEKTVPASIRLKRPLKMEDP---ICENEILETLHAIASKNQ-IWRSYIGMGYYNCSVPQTILRNLLENSGWVTQYTPYQPEVSQGRLESLLNYQTMVSDITGLDMANASLLDEATAAAEAMQLCHRHNKRK--KFFVDPRCHPQTIAVVQTRAKYRGVLVELKLPHEMD-----FSGKDVCGVLFQYPDTEG---KVEDFTELVDRAHQTGSLTCCATDLLALCILRPPGEFGVDIALGNSQRFGVPLGYGGPHAAFFAVKENLVRMMPGRMVGVTRDATGKEVYRLALQTREQHIRRDKATSNICTAQALLANMAAMFAIYHGSQGLKHIAKRVHNATLILSEGLKR--AGHQLQHDLFFDTLKVQCG--CSVKEVLGRAAQRQ-INFRLFDDGTLGISLDETVTEKDLDDLLWIFGCESSAELVAEGMGEERRGLLGSSFKRTSPFLTHQVFNSYHSETNLVRYMKKLENKDISLVHSMIPLGSCTMKLNSSSELAPITWREFANIHPFVPLDQAQGYQQLFQGLEKDLCEITGYDRVSFQPNSGAQGEYAGLATIRAYLDQKGERHRTVCLIPKSAHGTNPASAHMAGMKIQPVEVDRYGNIDVAHLKAMVDQHKENLAAIMITYPSTNGVFEENIGDVCALIHQHGGQVYLDGANMNAQVGICRPGDFGSDVSHLNLHKTFCIPHGGGGPGMGPIGVKKHLSPFLPSHPVISIKPTEG-TWPVGTVSAAPWGSSSILPISWAYIKMMGGKGLKEATEIAILNANYMAKRLEKHYRVLFRGARG---YVAHEFILDTRPFKKSANVEAVDVAKRLQDYGFHAPTMSWPVAGTLMIEPTESEDKAELDRFCDAMISIRQEIADIEEGRIDPRVNPLKMSPHSLT-CVTSSCWD-RPYSREVAAFPLPFVKPENKFWPTIARIDDIYGDQHLVCTCPPMEVYESPFSEQKRASS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23378-1", "uniprot_id": "GCSP_HUMAN", "id": "P23378-1", "name": "Glycine dehydrogenase (decarboxylating), mitochondrial", "aln": "MQSCARAWGLRLGRGVGGGRRLAGGSGPCWAPRSRDSSSGGG-----DSAAAGASRLLERLLPRHDDFARRHIGPGDKDQREMLQTLGLASIDELIEKTVPANIRLKRPLKMEDP---VCENEILATLHAISSKNQ-IWRSYIGMGYYNCSVPQTILRNLLENSGWITQYTPYQPEVSQGRLESLLNYQTMVCDITGLDMANASLLDEGTAAAEALQLCYRHNKRR--KFLVDPRCHPQTIAVVQTRAKYTGVLTELKLPCEMD-----FSGKDVSGVLFQYPDTEG---KVEDFTELVERAHQSGSLACCATDLLALCILRPPGEFGVDIALGSSQRFGVPLGYGGPHAAFFAVRESLVRMMPGRMVGVTRDATGKEVYRLALQTREQHIRRDKATSNICTAQALLANMAAMFAIYHGSHGLEHIARRVHNATLILSEGLKR--AGHQLQHDLFFDTLKIQCG--CSVKEVLGRAAQRQ-INFRLFEDGTLGISLDETVNEKDLDDLLWIFGCESSAELVAESMGEECRGIPGSVFKRTSPFLTHQVFNSYHSETNIVRYMKKLENKDISLVHSMIPLGSCTMKLNSSSELAPITWKEFANIHPFVPLDQAQGYQQLFRELEKDLCELTGYDQVCFQPNSGAQGEYAGLATIRAYLNQKGEGHRTVCLIPKSAHGTNPASAHMAGMKIQPVEVDKYGNIDAVHLKAMVDKHKENLAAIMITYPSTNGVFEENISDVCDLIHQHGGQVYLDGANMNAQVGICRPGDFGSDVSHLNLHKTFCIPHGGGGPGMGPIGVKKHLAPFLPNHPVISLKRNED-ACPVGTVSAAPWGSSSILPISWAYIKMMGGKGLKQATETAILNANYMAKRLETHYRILFRGARG---YVGHEFILDTRPFKKSANIEAVDVAKRLQDYGFHAPTMSWPVAGTLMVEPTESEDKAELDRFCDAMISIRQEIADIEEGRIDPRVNPLKMSPHSLT-CVTSSHWD-RPYSREVAAFPLPFVKPENKFWPTIARIDDIYGDQHLVCTCPPMEVYESPFSEQKRASS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VH09-1", "uniprot_id": "Q9VH09_DROME", "id": "Q9VH09-1", "name": "Glycine cleavage system P protein", "aln": "------------------MQRFLGRSSQSLLLRCG-------------HRYLATTPVEEVIFPTKSDFPSRHIGPRKTDVVAMLDTLGFKSLAELTEKAVPQSIQLKRELDLDKP---LNEHELIRRIRDISLKNQ-LWRSYIGMGYHNCHVPHTIIRNMFENPGWTTQYTPYQPEIAQGRLESLLNYQTLVTDLTGLDVANASLLDEGTAAAEAMCLATRHNKRK--KLYLSNRVHPQTLSVVKTRTEALELEIVVGPIEQAD-----LPSRELAGILLQYPDTYG---DVKDFEDIAALAKKNGTLVVVATDLLSLTLLRPPAEFGADIAVGTSQRLGVPLGYGGPHAGFFACKQSLVRLMPGRMIGVTRDMDGNDAYRLALQTREQHIRRDKATSNICTAQALLANMSAMYAIYHGPEGLKAMANRIHHFTLTLQTGVLG--AGHEVINKNFFDTLHIRLGGGQSLEDLKERAEHKR-INLRYLEDDTVGVALDETVSVADVDDLLWVFKAEASVEHILARKDVLKNSIENSKFLRTSPYLQHPIFQSYHSESRMVRYMKKLENKDISLVHSMIPLGSCTMKLNSTTEMMPCSFRHFTDIHPFAPVEQAQGFHQMFKELEHDLCEITGYDRISFQPNSGAQGEYAGLRAIRSYHEHRNEGHRNICLIPISAHGTNPASAQMAGMKVEPIRILSNGSIDMAHLRAKAEEHAHELSCLMITYPSTMGVFEETVADICTLIHKHGGQVYLDGANMNAQVGLCRPGDYGSDVSHLNLHKTFCIPHGGGGPGMGPIGVKAHLAPYLPGHPVVSPLSSE--EHSFGVVSAAPFGSSAILPISWSYIKLMGSRGLKRATQVAILNANYMSKRLEQHYKTLYKAPNSQ--LVAHEFILDIRDLKKSANIEAVDVAKRLMDYGFHAPTMSWPVAGTLMIEPTESEDKEELDRFCDAMISIREEIAEIEAGRMDKAVNPLKMSPHTQA-QVISDKWD-RPYTREQAAFPAIFVKPDAKIWPTVGRIDDAYGDKHLVCTCPPILPDL-----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P49095-1", "uniprot_id": "GCSP_YEAST", "id": "P49095-1", "name": "Glycine dehydrogenase (decarboxylating), mitochondrial", "aln": "-MLRTRVTALLCRATVRSSTNYVSLARTRSFHSQSILLKTAATDITSTQYSRIFNPDLKNIDRPLDTFARRHLGPSPSDVKKMLKTMGYSDLNAFIEELVPPNILKRRPLKLEAPSKGFCEQEMLQHLEKIANKNHYKVKNFIGKGYYGTILPPVIQRNLLESPEWYTSYTPYQPEISQGRLEALLNFQTVVSDLTGLPVANASLLDEGTAAGEAMLLSFNISRKKKLKYVIDKKLHQQTKSVLHTRAKPFNIEIIEVDCSDIKKAVDVLKNPDVSGCLVQYPATDGSILPPDSMKQLSDALHSHKSLLSVASDLMALTLLKPPAHYGADIVLGSSQRFGVPMGYGGPHAAFFAVIDKLNRKIPGRIVGISKDRLGKTALRLALQTREQHIKRDKATSNICTAQALLANVASSYCVYHGPKGLQNISRRIFSLTSILANAIENDSCPHELINKTWFDTLTIKLGNGISSEQLLDKALKEFNINLFAVDTTTISLALDETTTKADVENLLKVFDIENSSQFLSEDYS---NSFP-REFQRTDEILRNEVFHMHHSETAMLRYLHRLQSRDLSLANSMIPLGSCTMKLNSTVEMMPITWPQFSNIHPFQPSNQVQGYKELITSLEKDLCSITGFDGISLQPNSGAQGEYTGLRVIRSYLESKGENHRNVCLIPVSAHGTNPASAAMAGLKVVPVNCLQDGSLDLVDLKNKAEQHSKELAAVMITYPSTYGLFEPGIQHAIDIVHSFGGQVYLDGANMNAQVGLTSPGDLGADVCHLNLHKTFSIPHGGGGPAGAPICVKSHLIPHLPKHDVVDMITGIGGSKSIDSVSSAPYGNALVLPISYAYIKMMGNEGLPFSSVIAMLNSNYMMTRLKDHYKILFVNEMSTLKHCAHEFIVDLREYKAKG-VEAIDVAKRLQDYGFHAPTLAFPVPGTLMIEPTESENLEELDRFCDAMISIKEEINALVAG--QPKGQILKNAPHSLEDLITSSNWDTRGYTREEAAYPLPFLR-YNKFWPTVARLDDTYGDMNLICTCPSVEEIANETE-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . : : . *. **:** .* **.::* .: : *: ** .* :* *.:: * . *:*:: :. *: **: :.:** **:. :* .* **::*.. * *.*******::*****:***:**:* *:*** :********.***.**: *. . .::: : :. : * ** :*::**:: : : . : . ::.* *.*** * * ..: :: :. :* *:**::* :*:**..:*.**.:*.***:***:*******.*** :.* * :***::*:::* *: . ***********:*****************::: :.:***..**: ::.*:. * * .: . *:: :. :**** :: * * ::: :* :. **: .: *:.::****.. *:::** :* * * : : . ..: * **. * : :*: :***: ::**:::*:.:*:**.:***** : * :: .*::**** * :*.**::::: **:***.:**:* :.:**********:** .**:* : :.* **.:**** ********** ***:*: *:. *.:* ..*: .::* .:*:.:******* *:** : . ::*..****************: *** *:**.********.********. .** ** ** *.** * :: ... **:**:*.: :****::***:**..** :: *:**:*** .**: :*: *: . .****:* * * .. :**:****** ********:::**.****:******: ************::** : * : : ** :**: : *. ** * *:** **:* *:: *:***:.*:** *** :*:****.: ", "identical_positions": 418, "similar_positions": 292, "identity": "39.81%" }, { "cls_id": "homologset.agr.RGD:1308662", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M2BHU6-1", "uniprot_id": "A0A8M2BHU6_DANRE", "id": "A0A8M2BHU6-1", "name": "", "aln": "--------------MLKRVSSNKSYSPYATSQ--------RVKKSSSKKKL------------------DILPNKPNVWL-----KQLSALQEQPRKDAVDSVTSSSQTSSSLSPPIVEVSSSCPGTPLTQHSKALGCPSPMGTLKRPTSLSRNPSAAGFPIQS---WVFSKGAGKSVIAQSPSPETADTTVAIEVEDIPSLLRSVERFAKAVEKLKDVVLEDKQEN--RRPLAHECLGEVLRVLRQVISMYPLLNTVETLTAAGKLISQVKGYHYESCIEPEKKDFEKAIETIAVAFSSNVSELLMGEVDSSTLLSVVPTEKSRSMENLS----GHGSSHTWGDSSELAMSAEEVDIILQRSEGGVDSALTYAKTISKYLKDLIGYVERKLALELEFSKGLQRIYQSCKQTITQP-HMPFFTIYSQALEQDLEQSNGMHQAAATLQNQTFIMPLMVRKQEHEKKRKEIKEQWLKAKRKLMECDVNLRRAKQVYMTRCEEYDKARTAANRAEEE-------GGSATTKTLDKKKRLEEEARNKAEEAEATYRTCIADAITQHQELEHMKVTVLRGIQEVIKQTDQTIRSATISYYQIMHMQTVALPVHYQTLCESSKQYDPGQQYGTHVKDLQMSEEPETHYEFEAYSAS-SVQQSVRPRTDS-ANAEAQSSAEVPQTAGETG---DTSSSQKDDQKRARGHMTHKSWGSTVSDTDSVGGGSGLESPTTSTGDISKMTRTSSTGTMSSNEDIDEKDA--NVTSFETPNINGIEPEI--VVPTGPFRNIGLSKAAQTHKLRKLRSPSKCRECDSYVYFQGAECEECFLACHKRCLETIAIQCGHKKLQGRLQLFGQDFLQVSSNSPDGIPFIIKKCIAEIERRALRMKGIYRVNGVKTRVEKLCQAFEN----GKELVELSQSSPHDISNVLKLYLRQLPEPIMPFRLYNSLMGLAKESLAVVGPEGADSGKGPDLMDLGPETDPELLVLVDRLKNLLKELPKPNTATLRYLARHLRRIAELEDDNKMSPSNLGIVFGPSLMRPRPSGATVSLSSLVDYPYQARIVETLIVFYPSIFQSESSRPASSSTRTQ-------------SLQQQSSIDEERCSNDEQGLPDEPAAVELDKLEDHAESCTGTPDSLEHSLDLDSDPEAEQPVDETSIQSRPAVLLVTLQS--------SSADPPALPESEPPELEDQSHSLAALNINQSNNTTKTLTS----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1QL19-1", "uniprot_id": "A0A8M1QL19_DANRE", "id": "A0A8M1QL19-1", "name": "", "aln": "-----------------------MFSRKKKEQ--------ATKTPTASKKS------------------NSAQNPS-----------LSILQEHSQNDTMD--------GSSMLTPPDSVALSCPGTP-CAHSRLSGCSSPVGTVRRPPGLSRHASAAGFPFQTSGTWGFHKGYVRAPLNYGQAAEGLETSV-IEVEDIPSLLRDVARFAEAVEKLKDMVLGEVKEEPRSRPAVHECLGEVLRVLRQVISTYPLLNTVETLTAAGTLISKVKGFSYEGTTDAQKKDFEKAIETIAVAFSSNVSELLMGEIDSTTLLSLPPTEKSRSMEDLYRLSSGQGPEGGGKYDQQDCISPQEVDILLQRSEGGVDSALSYSKSIAKYMKDIISYVDKRIALENEFSKGLQRLYQSCKQNIIQD-HMPLLSIFSLALEQDSEQSCGLQQTTNNIYTHSFLQPMTQRRQEHEKKRRDIKEQWQRAKRKLADAESNLRKARQLYMSRCEEYERARTVANKVEEEQSGT---GSGSTTKALDRKRRLEEEARNKAEEAEATYRTCIADATTQQQELEDMKVNVLKQIQELIRQTDQILRACTISYYQTMHVQTAALPVHFQTLCESCKLFDPGQQYAAYVKNLQLRTERPLQYQFEPYSAS-SHQQLLRTRNNSLSNDQRQNSCEAPTTPEEAGFGEGTVVKQRRGQVRDH-HQAHKSWPSTLSDTDSVGPGSGLGSPTNSTGDISKPSRPVSAATLSSNEDLEERDG--AMTQFEQS-INGIEPEI--VAPTGPFRNVGLSKAAKTHRLRKLRTPSKCRECDSYVYFQGAECEECFLACHKKCLESLAIQCGHKKLQGRLQLFGRDFSQVLHGKEDAVPFIIKKCITEIERRALKMKGIYRVNGVKTRVEKLCQAFEN----GKELVELSQASPHDISNVLKLYLRQLPEPIMPFRMYNELMGLAKESLNSDASESTDGVKSPELVDRGPETEAEVLTLVDKLREVLKRLPNANIATLKYIIQHLRRVSELEQENKMSASNLGIVFGPTLMRPKPTGATVSLSSLVDYPHQARIVEALIVFQQSIFICTTKSPAQRQDSET-------------GAHEEPIRAHQECGETAHGDSVGSSGSQERSLDSDSDVEDPAAGFRPHRPPLVSQ-ESETSTEEDQLSPR-----ASLDL--------SGLVPETIPEQSVPEPAENTSGRSQQ------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ABK0L8V3-1", "uniprot_id": "A0ABK0L8V3_RAT", "id": "A0ABK0L8V3-1", "name": "", "aln": "MRSGFWNVPDCVEDPGTFLVQPEAHPRASQSSNRHNLSNPLPSQPTMSGRRGPLKELLGWVCGWTRAWRTRLGTTGCGLSGLCPGEPPSVSEELPRKD--------CTETPSLEPPAMSLSTVAKGTG---------------TLKRPTSLSRHASAAGFPLSGTATRTLGRGYRSPLSAASPAELPTEGPFPDGVEDISTLLADVARFAEGLEKLKEFVLRDDLLEA-RRPLAHECLGEALRVMRQVISKYPLLNTVETLTAAGTLIAKVKAFHYECNNESDKREFEKALETIAVSFSCTVSEFLLGEVDSSTLLAVPPGDPSQLVENLYG-SGSEGPPHSVEDCEEGCLPPEEVDMLLQRCEGGVDAALQYAKDMARYMKDLIGYLEKRTTLEMEFAKGLQKVVHNCRQNVTHAPHMPLLSIYSLALEQDLEFGHGMVQAVGTLQTQTFMQPLTLRRLEHERRRKEIKESWHRAQRKLQEAEANLRKAKQGYKQRCEDHDKARLQVAKAEEEQQGTGPGAGTAASKALDKRRRLEEEAKNKAEEAMATYRTCVADAKTQKQELEDTKVTALRQIQEVIRQSDQTIKSATISYYQLMHMQTAPLPVNFQMLCESSKLYDPGQQYASHVRQLQRGEEPDVRYDFEPYVSTNAWSPIMRTRKGSFNPGDASGPEAAGSPPEEGGTSEGAPNKDHRG---GRGHQVHKSWPISISDTE-----VSLDVS---SGDLKKFDRTSSSGTMSSNEELVDQEAGLVASAFDSADLNGMDPELPVAMPSGPFRHVGLSKAARTHRLRKLRTPAKCRECNSYVYFQGAECEECCLACHKKCLETLAIQCGHKKLQGRLQLFGQDFSQAAHSTPDGVPFIIKKCVCEIERRALHTKGIYRVNGVKTRVEKLCQAFEN----GKELVELSQASPHDISNVLKLYLRQLPEPLISFRFYHELVGLAKDSLKAEAEAKAASRGR----QDGSESEAATLAMVGRLRELMRDLPAENRATLLYLLRHLRRIVEMEQDNKMTPGNLGIVFGPTLLRPRPTDATVSLSSLVDYPHQARVIETLIVHYGLVFEEEPEEAAGSQEGAS-------AQCAQLETAEGIVFPQQEEADDGNRESQVASNDSDSELEEASDLLSSSDASALHRLSFLEQ--TEAGLEEGPQSHSGSE--EQLES--------EDAAPGHQLCSFNTNQSNNTTQASLPTMRLRDGQITGGSGRKRQPQFV--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TBD2-1", "uniprot_id": "HMHA1_MOUSE", "id": "Q3TBD2-1", "name": "Rho GTPase-activating protein 45", "aln": "-----------------------MFSRKKRE---------LMKTPSISKK-------------------NRAGSP----------NPQSSSGELPRKD--------WTEAPGLEPPATSLSTVAKGTG---------------TLKRPTSLSRHASAAGFPLSGTATWTLVRGYRSPLSAASPAELPTEGAFPDGVEDISTLLADVARFAEGLEKLKECVLQDDLLEA-RRPLAHECLGEALRVMRQVISRYPLLNTVETLTAAGTLIAKVKAFHYECNNESDKREFEKALETIAVSFSCTVSEFLLGEVDSSTLLAVPPGDPSQSMENLYG-AGTEGPPHNVEECEEGCLPPEEVDMLLQRCEGGVDAALQYAKDMARYMKDLISYLEKRTTLEMEFAKGLQKVVHNCRQSVTHEPHMPLLSIYSLALEQDLEFGHGMVQAAGTLQTQTFMQPLTLRRLEHERRRKEIKESWHRAQRKLQEAEANLRKAKQGYKQRCEDHDKARLQVAKAEEEQQGTGPGAGTAASKALDKRRRLEEEAKNKAEEAMATYRTCVADAKTQKQELEDTKVTALRQIQEVIRQSDQTIKSATISYYQLMHMQTAPLPVNFQMLCESSKLYDPGQQYASHVRQLQRGEEPDVRYDFEPYVSNNSWSPIMRTRKGSFNPGDASGPEAAGSPPEEGGTSEAAPNKDHRG---GRGHQVHKSWPISISDTE-----VGLDTS---SGDLKKFDRTSSSGTMSSSEELGDQEAGLVASAFDSADLNGMDPELPVAMPSGPFRHVGLSKAARTHRLRKLRTPAKCRECNSYVYFQGAECEECCLACHKKCLETLAIQCGHKKLQGRLQLFGQDFSQAALSTPDGVPFIVKKCVCEIERRALHTKGIYRVNGVKTRVEKLCQAFEN----GKELVELSQASPHDISNVLKLYLRQLPEPLISFRFYHELVGLAKDSLKAEAEAKAASRGR----QGGSESEAATLAMVGRLRELMQDLPAENRATLLYLLKHLRRIVEMEQDNKMTPGNLGIVFGPTLLRPRPTDATVSLSSLVDYPHQARVIETLIVHYGLVFEEEPEEAPGSQEGAS-------TQCGQLESAEGIVFPLQEEAEDGSRESHAASNDSDSELEDASDPLSSSDASALHRLSFLEQ--TEAGLEEGPQSHSGSE--EQLEG--------EDGAPGPWLCHFNTNQSNNTSRAPLPTMRLRGGQITGGTSQERQPQFV--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92619-1", "uniprot_id": "HMHA1_HUMAN", "id": "Q92619-1", "name": "Rho GTPase-activating protein 45", "aln": "-----------------------MFSRKKRE---------LMKTPSISKK-------------------NRAGSP-----------SPQPSGELPRKDGADA----VFPGPSLEPPAG--SSGVKATG---------------TLKRPTSLSRHASAAGFPLSGAASWTLGRSHRSPLTAASPGELPTEGAGPDVVEDISHLLADVARFAEGLEKLKECVLRDDLLEA-RRPRAHECLGEALRVMHQIISKYPLLNTVETLTAAGTLIAKVKAFHYESNNDLEKQEFEKALETIAVAFSSTVSEFLMGEVDSSTLLAVPPGDSSQSMESLYG-PGSEGTPPSLEDCDAGCLPAEEVDVLLQRCEGGVDAALLYAKNMAKYMKDLISYLEKRTTLEMEFAKGLQKIAHNCRQSVMQEPHMPLLSIYSLALEQDLEFGHSMVQAVGTLQTQTFMQPLTLRRLEHEKRRKEIKEAWHRAQRKLQEAESNLRKAKQGYVQRCEDHDKARFLVAKAEEEQAGSAPGAGSTATKTLDKRRRLEEEAKNKAEEAMATYRTCVADAKTQKQELEDTKVTALRQIQEVIRQSDQTIKSATISYYQMMHMQTAPLPVHFQMLCESSKLYDPGQQYASHVRQLQRDQEPDVHYDFEPHVSANAWSPVMRARKSSFNVSDVARPEAAGSPPEEGGCTEGTPAKDHRA---GRGHQVHKSWPLSISDSD-----SGLDPGP-GAGDFKKFERTSSSGTMSSTEELVDPDGGAGASAFEQADLNGMTPELPVAVPSGPFRHEGLSKAARTHRLRKLRTPAKCRECNSYVYFQGAECEECCLACHKKCLETLAIQCGHKKLQGRLQLFGQDFSHAARSAPDGVPFIVKKCVCEIERRALRTKGIYRVNGVKTRVEKLCQAFEN----GKELVELSQASPHDISNVLKLYLRQLPEPLISFRLYHELVGLAKDSLKAEAEAKAASRGR----QDGSESEAVAVALAGRLRELLRDLPPENRASLQYLLRHLRRIVEVEQDNKMTPGNLGIVFGPTLLRPRPTEATVSLSSLVDYPHQARVIETLIVHYGLVFEEEPEETPGGQDESSNQRAEVVVQVPYLEAGEAVVYPLQEAAADGCRESRVVSNDSDSDLEEASELLSSSEASALGHLSFLEQQQSEASLEVASGSHSGSE--EQLEATAREDGDGDEDGPAQQLSGFNTNQSNNVLQAPLPPMRLRGGRMTLGSCRERQPEFV--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q12128-1", "uniprot_id": "BAG7_YEAST", "id": "Q12128-1", "name": "Rho-GTPase-activating protein BAG7", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFNMNLLSTPSSEEGSPQNRSSSMSSVEGKKDRDTFTNLQNEFDGKVFGVSLEESLKVAQEEV---------------IIQKSTNEIGSIPVVIAKSGKYLKENALDTTGIFRIAGSNKRVRELQAVFSKPPDYGRKFEGWCDFNVHDIATLLKRYLNSLSEPLVPLALYDIFRNPILE---------------------NPKINEHKEQIIKDYEDIYMLLPQQNRHLILYLAALLNLFARNEKKNLMSASNLAAIVQPSLLSHPKDEMCP-----KEYEASRTVIEFLILHASDIIPNTEKANKDTMPHAG-------------TVAKFNNITVPEMAIDSDEEDFVHPSIDDHMLPR-SRALSDSNNFTIHHHHHHHHALFPSPIDFDNNGLSVPRSFKGRTLSAESLSPRLSKLLGNVGNSSNTGIKDPTERVPRGEHKTKHKQRQSWLRRLTSPSRTQP", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . .:.: :: .: : :: :::. :*. : .. :..*: : : : . ..:*.:: *. ::..** .**:*: * :.**.:* .*.: *::: .: . ***:.:** **..*.**::.: :*. : . : ..: : : .:: ** * : *: *. . . *..* *:..**. :. *:*: :* . ::* **:. :: . : . . . . * : : . : . : . ", "identical_positions": 43, "similar_positions": 117, "identity": "3.46%" }, { "cls_id": "homologset.agr.RGD:1308665", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AV56-1", "uniprot_id": "A0A8I6AV56_RAT", "id": "A0A8I6AV56-1", "name": "GATOR complex protein NPRL3", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGDNTSPISVILVSSGS--------------------------------------------RGNKLLFRYP---------------------------------------------FQRSQEHPASQTNKPRSR----YAVNNTGEHVDDQD--GDSSK------PCPPTDEQLVAGFSDAILATILATKSEMCGQKFELKIDNVRFVGHPTLLQ---------------------------------------------------------HALGQVSKTDPS----------------PKREAPTMILFNVVFALR---ANADPSVINCLHTLSRRIATVLQHEERRCQYLTREAKLILALQD-------EVSAMADANEGPQSPFHHILPKCKLARDLKEAYDSLCTSGVVRLHINSWLEVSFCLPHKIHYAAS---------------SLIPPEAIERSLKAIRP------------------------------------------------------YHALLLLSDEKSLLSELPIDCSPALVRVIKTTSAVKNLQQ------------------------LAQDADLALLQVFQLAAHLVYWGKAVIIYPLCENNVYVLSPNASVC----------------------------------LYSPLAEQFSRQFPSHDLPSVLAKFSLPVSLSEFRSPLAPPAQETQLIQMVVWMLQRRLLIQLHTYVCLMASP-----------------SEEE--PRPREDDVP-FTARVGGRSLSTPNALSFG---------SPTSSDDMTLTSPSMDNS--------SAELLPSGDSPLNKRMTENLLASLSEHERAAILNVPAAQNPEDLRMFARL--LHYFRGRHHLEEIMYNENTRRS--QLLMLFDKFRSVLVVTTHEDPVIAVFQALLT----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VIJ8-1", "uniprot_id": "NPRL3_MOUSE", "id": "Q8VIJ8-1", "name": "GATOR1 complex protein NPRL3", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGDNTSPISVILVSSGS--------------------------------------------RGNKLLFRYP---------------------------------------------FQRSQEHPASQTNKPRSR----YAVNNTGEHADDQD--GDSR-------------------FSDVILATILATKSEMCGQKFELKIDNVRFVGHPTLLQ---------------------------------------------------------HALGQVSKTDPS----------------PKREAPTMILFNVVFALR---ANADPSVINCLHNLSRRIATVLQHEERRCQYLTREAKLILALQD-------EVSAMADANEGPQSPFQHILPKCKLARDLKEAYDSLCTSGVVRLHINSWLEVSFCLPHKIHYAAS---------------SLIPPEAIERSLKAIRP------------------------------------------------------YHALLLLSDEKSLLSELPIDCSPALVRVIKTTSAVKNLQQ------------------------LAQDADLALLQVFQLAAHLVYWGKAVIIYPLCENNVYVMSPNASVC----------------------------------LYSPLAEQFSRQFPSHDLPSVLAKFSLPVSLSEFRSPLAPPAQETQLIQMVVWMLQRRLLIQLHTYVCLMASP-----------------SEEE--PRLREDDVP-FTARVGGRSLSTPNALSFG---------SPTSSDDMTLTSPSMDNS--------SAELLPSGDSPLNKRMTENLLASLSEHERAAILNVPAAQNPEDLRMFARL--LHYFRGRHHLEEIMYNENTRRS--QLLMLFDKFRSVLVVTTHEDPVIAVFQALLT----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q12980-1", "uniprot_id": "NPRL3_HUMAN", "id": "Q12980-1", "name": "GATOR1 complex protein NPRL3", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRDNTSPISVILVSSGS--------------------------------------------RGNKLLFRYP---------------------------------------------FQRSQEHPASQTSKPRSR----YAASNTGDHADEQD--GDSR-------------------FSDVILATILATKSEMCGQKFELKIDNVRFVGHPTLLQ---------------------------------------------------------HALGQISKTDPS----------------PKREAPTMILFNVVFALR---ANADPSVINCLHNLSRRIATVLQHEERRCQYLTREAKLILALQD-------EVSAMADGNEGPQSPFHHILPKCKLARDLKEAYDSLCTSGVVRLHINSWLEVSFCLPHKIHYAAS---------------SLIPPEAIERSLKAIRP------------------------------------------------------YHALLLLSDEKSLLGELPIDCSPALVRVIKTTSAVKNLQQ------------------------LAQDADLALLQVFQLAAHLVYWGKAIIIYPLCENNVYMLSPNASVC----------------------------------LYSPLAEQFSHQFPSHDLPSVLAKFSLPVSLSEFRNPLAPAVQETQLIQMVVWMLQRRLLIQLHTYVCLMASP-----------------SEEE--PRPREDDVP-FTARVGGRSLSTPNALSFG---------SPTSSDDMTLTSPSMDNS--------SAELLPSGDSPLNQRMTENLLASLSEHERAAILSVPAAQNPEDLRMFARL--LHYFRGRHHLEEIMYNENTRRS--QLLMLFDKFRSVLVVTTHEDPVIAVFQALLP----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VUB4-1", "uniprot_id": "NPRL3_DROME", "id": "Q9VUB4-1", "name": "GATOR complex protein NPRL3", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------METNVNPLAVILVYFDS--------------------------------------------KGDRLLYRYP---------------------------------------------YQTLGQTEVANDEQRKSRKRNPYAVANTDDLLQTPTHLGAAK------------SQGQLQGFADEVLSALFAVKPQLCNQKFELKLNDVRFVSHPTLIP---------------------------------------------------------QKE---QRSGPM----------------AKQ----QMLINIVFALH---AQASYSIVKCYHELSKRLGLALKFEEQRSGYLTEQTAQMARTHD-------EQQQQP-----LERTLELIAERCSLAQALRSIFHDLCTTGLLSTSLNHNLTLCFCLPAKAHQLHKK-------------GSMVDPETIDRCLRALKP------------------------------------------------------YHGMLLLVDFAELLDCVPPTGARMLWQLVDVYDPLISLQS------------------------MSSNADLSIEHVYKLVSHLVYWAKATIIYPLCETNVYVIAPDAPLH----------------------------------TKSHLVEKFSARFAGMSLFEVISDFSLPTSIGHLTTPLQQPARQGILAQMVIWMLQHHLLMQLHTYVQFMPSEDEFGDSASCSNHLRDAISDEEGDQEPDADELHGSMLSMSSHPLPVPAVLVGGHRREASEDHSSLASDNIAVQPSSSHKSNFSITASMSTDNCDSLDSMEDEQKLKELLQVFSDADRAAIRRIPASANVDDLSLLVKLYQMGYFKSEHHLEEIMYFENLRRS--QLLQLLDKFRDVLIIYETEDPAIASMYNTK-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38742-1", "uniprot_id": "NPR3_YEAST", "id": "P38742-1", "name": "Nitrogen permease regulator 3", "aln": "MDECLPNSCLLGVHLVISTHSGPQIVYHYPPSNTAFLTNNPTKHQHLYGNHANLNKNTSTNKEEKLFNSGSTKTASQIALNESAKSYNTAITPSMTNTNTNNVTLPPTRSHANTVGSQSSIPAATNGVGYRKTDIEDTSRTFQYQETESETSSSGLSDSELSTDYLDISSDSFSISSSLSSSSLSSSPSSSSSSSPPQDGLSRTNSSFQSTDSMSPTSPQMIMENDSISVAESYLDSGTNNKSRAASKRSQNFFHKLSTKKSTDSKTHSPVRKLKSKPSQSTKKGNKLLKNTSNETDGNAFTGSCSISSKKSLSSTGEHNQELRNSSLNDTPGQSPHHYHHRYHHYHKNAATSQRNSHTQYDVEEEDMEVSAMLQDGKISMNEIFFEEENFQDINKILEFDNDFVAEFCSPEREMCNTRFEFTVDNFCFLGLPIHVDSQGRWRKSKHKNKTRSKRSSSTTTNISRKKSIASKISSLSENTLKKVNSGEADTVYDSNIGHEASTDTPNLRINTDVSGNEFEREKEDLGKNMNMFHVCFVMNPHLIEYNKRIDDMYQFVVTRLSLLLRYVQSKTSYISSECHIILKEKERVLKHSKTYQSIRGAGNKGKYLYQRILAKSSLARALTECVDKIQRNEIACLEINDDKVISLQIPIQNEFEKMPNFKLQPVLRGSYLTSILNMKFLEKSSLRIESQNRQNDQAQFSDTNNNIYRFGNNINSTGHCGAANVDDGDDNESNYYCDDNDDLLNYALLLLDEPNNIISSLETFSYQDDIGTIILKHLVRNIQPNIPLRSYRYLITDLLDNPSSLDDLTTETNSLESSILRSCALHLMYWRHARIVIPLSSKYTYIVSPLAPIQGYTIDDYKSTSQNDGNVKKMDDRENNKSGSDRVPLIYQNSMLFRSKFPSLPSLPIFLSLLSTDKPQAYSNIIPSREHKPVYLNALAWLIQYGYVTQLLTFINIRVDK--------HIKMAVDEDLEKEGFRKTNTARRPSMDYKKTDKKLDDEDGQSRDAN------ASEACSGKNEGMQSNDNNKDVDEKDNENDSRVDDRDDNEIAIADEEEILHFEYDDPEMQHDYTIILEPERATAIEKRWLYRCIYGQPSDIQILFNKLLKYFNGKVPMELVIIKEEISRHDLKKLLNALDKYLIEIHHW", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : .:: : .: :*::** . . :: . : : . * . : . . * * : .:: : : : ::*. :**:.:::. *:. * : :.. : :::: *.:. : . : . : : *:. *:. : : *:: : : :: . : . * :..**: * . ..: . : :* :.: :* : . *:: : :::. :.. :.:*** : .::. : : : .:* :. .* : . . **:** :* *: **... .*:::* *.: * :*.. :: .: . . . : :: : : *::* : ** *:: : . ::* . .: * . * .*.. .. .:. . . . *. :: : :. : . : : : : : .. :*:: : : :: : ::. : :. * ", "identical_positions": 53, "similar_positions": 200, "identity": "4.57%" }, { "cls_id": "homologset.agr.RGD:1308666", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CQW3-1", "uniprot_id": "PROZ_MOUSE", "id": "Q9CQW3-1", "name": "Vitamin K-dependent protein Z", "aln": "MAGCILLLRGFIL----TLILHQVELSVFLPAPKANNVLRRWRRGSSYFLEEIFQGNLEKECYEEVCNYEEAREVFENDVITDEFWRQYGGGSPCVSQPCLNNGTCEDHIRSYSCTCSPGYEGKTCAMAKNECHLERTDGCQHFCHPGQSSYMCSCAKGYKLGKDQKSCGPSDKCACGALTSEHIRMTKSS-----------QSQPSFPWQVRLTNSEGEDFCAGVLLQEDFVLTTAKCSLLHSNISVKANVDQR--------IRIKSTHVHMRYDEESGENDVSLLQLEEPLQCPSSGLPVCVPERDFAEHVLIP-GTEGLLSGWMLN--GTHLATTPMLLSVTQADGEECGQTLNVTVTTR--TSCEKGSVVMGPWVEGSVVTREHKGTWFLTGILGSPPPPGQSQMLLLTAVPRYSMWFKQIMK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3V8K8-1", "uniprot_id": "G3V8K8_RAT", "id": "G3V8K8-1", "name": "Vitamin K-dependent protein Z", "aln": "MADCISLHRGFILSFVLTLALHQVELSVFLPASEANNILLRWRRASSYLLEEFLQGNLERECYEEICNLEEAREVFENDASTDEFWSQYSGGFPCISQPCLNNGTCKDHIRSFSCTCAPGYEGKTCAMAKNECHLERTDGCQHFCHPGQSSYMCSCAKGYKLGEDHRSCSPSDKCACGALTSQHIRTQMTDD--------ICRSWPSFPWQVRLTNSEGEDFCAGVLLQENFVLTTAKCSLLHSNLSVKADDDQQ--------IRIKSAHVHMRYDKETGENDVSLLELEKPLQCPIPALPVCVPERDFAEHVLIP-GTKGVLSGWMLN--GIDLDRTLTMLSVTQTDGEECGQILNVTVTTR--TSCEKGSEVMGPWVEGSVVTRQHKGTWFLTGILSSPPPPGQSHMLLLTSVPRYSMWFNQIMK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P22891-1", "uniprot_id": "PROZ_HUMAN", "id": "P22891-1", "name": "Vitamin K-dependent protein Z", "aln": "MAGCVPLLQGLVL----VLALHRVEPSVFLPASKANDVLVRWKRAGSYLLEELFEGNLEKECYEEICVYEEAREVFENEVVTDEFWRRYKGGSPCISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQHFCLPGQESYTCSCAQGYRLGEDHKQCVPHDQCACGVLTSEKRAPDLQD----------------LPWQVKLTNSEGKDFCGGVIIRENFVLTTAKCSLLHRNITVKTYFNRTSQDP--LMIKITHVHVHMRYDADAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIP-RTRGLLSGWARN--GTDLGNSLTTRPVTLVEGEECGQVLNVTVTTR--TYCERSSVAAMHWMDGSVVTREHRGSWFLTGVLGSQPVGGQAHMVLVTKVSRYSLWFKQIMN-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1Q5S2-1", "uniprot_id": "F1Q5S2_DANRE", "id": "F1Q5S2-1", "name": "", "aln": "MACLGIYLSLAVLFGFVTAGLHKRSAPVFLEKWDALNVISRQKRSNTGDEETKLPANLERECLEEVCDYEEAREVFQDNYRTDIFWSVYIDGDQCADQPCKNGAMCSDSVGGYDCICKSGFTGTHCETDQTVCLIDKSKGCSQFCKPGYHSYECSCAYGWKLQQKEK-CVPAVTFPCGKVGSVSQWERRQSENIKSEYEGFPCGPEECPWQAMLLRGSS-GFCSGVILKENLVLTTAQCARKHPDFQVAVGKRMTMFESSGQTLAVRQVHLHPLHSTGTAENDLALLELRDRIIFKKSVAAACLPERDFADRVLTAGQYMGVVTGWKDTPTEDGIEGHLLLNHLSYQTLQDCSRQHSAQVSSNKLMCSLPRAKADCVFGQGSPVLTLHREVFFLTGMVSRPAGADCRSGYILQKVSRALPWLNSIMSP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** :* . **: . .*** .* ::: * :*..: * : .***:** **:* *******::: ** ** * .* * .*** :.. *.* : .: * * .*: *. * :. * :::.**.:** ** ** **** *::* :..: * * .** : * . ***. * .... .**.**:::*::*****:*: * :: * . : : .*:* :. :.***::**:*. : . ..* **:***:::* . *:::** . : :: ::*.: .. *::. . : . : :** * *: :****::. . . :: *.* *::.**. ", "identical_positions": 114, "similar_positions": 122, "identity": "26.64%" }, { "cls_id": "homologset.agr.RGD:1308667", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZQ25-1", "uniprot_id": "D3ZQ25_RAT", "id": "D3ZQ25-1", "name": "Fibulin-1", "aln": "MERPAPSRLVPLPLLLLGSLSLLAARANADISMEACCTEGNQMANQHRDCS-LSYTSESKECRMVQEQCCHNQLEELHCATGINLASEPDGCASLHNYNSSLETIFIKRCCHCCMLG-RAAQARGQTCEPNLMISYQCGLVFRACCVKGQENSDFVRGDGTDLQDPAKIPE-EEEQEDPYLNDRCRGGGPCKQQCRDTGDEVICSCFVGYQLQSDGVSCEDINECITGSHNCRLGESCINTVGSFRCQRDSSCGTGYELTEDNNCKDIDECETGIHNCPPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPVGQTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECSPPAEPCGKGHHCLNSPGSFRCECKAGYYFDGISRTCVDINECQRYPGRLCGHKCENTPGSYHCSCSAGFRLSVDGRSCEDVNECLNSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGSFRCLSFECPENYRRSADT-FRQEKTDTVRCIKSCRPTDEACMRDPVHTVSHTVISLPTFREFTRPEEIIFLRAVTPLYP--ANQADIIFDITEGNLRDSFDIIKRYEDGMTVGVVRQVRPIVGPFYAVLKLEMNYVLGGVVSHRNVVNVHIFVSEYWF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q08879-1", "uniprot_id": "FBLN1_MOUSE", "id": "Q08879-1", "name": "Fibulin-1", "aln": "MERPVPSRLVPLPLLLLSSLSLLAARANADISMEACCTDGNQMANQHRDCS-LPYTSESKECRMVQEQCCHNQLEELHCATGINLASEPEGCASLHSYNSSLETIFIKRCCHCCMLG-KASLARDQTCEPIVMISYQCGLVFRACCVKARENSDFVQGNGADLQDPAKIPD-EEDQEDPYLNDRCRGGGPCKQQCRDTGDEVICSCFVGYQLQSDGVSCEDINECITGSHNCRLGESCINTVGSFRCQRDSSCGTGYELTEDNNCKDIDECETGIHNCPPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPVGQTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECSPPAEPCGKGHHCLNSPGSFRCECKAGFYFDGISRTCVDINECQRYPGRLCGHKCENTPGSFHCSCSAGFRLSVDGRSCEDVNECLNSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGSFRCLSFECPENYRRSADT-FRQEKTDTVRCIKSCRPNDEACVRDPVHTVSHTVISLPTFREFTRPEEIIFLRAVTPLYP--ANQADIIFDITEGNLRDSFDIIKRYEDGMTVGVVRQVRPIVGPFYAVLKLEMNYVLGGVVSHRNVVNVHIFVSEYWF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23142-1", "uniprot_id": "FBLN1_HUMAN", "id": "P23142-1", "name": "Fibulin-1", "aln": "MERAAPSRRVPLPLLLLGGLALLAAGVDADVLLEACCADGHRMATHQKDCS-LPYATESKECRMVQEQCCHSQLEELHCATGISLANEQDRCATPHGDNASLEATFVKRCCHCCLLG-RAAQAQGQSCEYSLMVGYQCGQVFQACCVKSQETGDLDVGG---LQETDKIIEVEEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAAT-LQQEKTDTVRCIKSCRPNDVTCVFDPVHTISHTVISLPTFREFTRPEEIIFLRAITPPHP--ASQANIIFDITEGNLRDSFDIIKRYMDGMTVGVVRQVRPIVGPFHAVLKLEMNYVVGGVVSHRNVVNVHIFVSEYWF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O42182-1", "uniprot_id": "FBLN1_DANRE", "id": "O42182-1", "name": "Fibulin-1", "aln": "------MDLYMIVLLSLCGL-LRAQETTDTISLDNCCEDGKKRGLESQDCSSLPLISESTTCRVVQEQCCSAVLEDSICTSGINMAKDQSSCDALLSGSSTCETKTTKMCCECCLLGSSRCRIRVSPVSSVCRWSISRGPGVRSCCVDKQ---------------PAHGVQ-PSKGDAQNTEDQCRAAG-CAQRCLNG----TCSCLDGFKLKTDGKHCEDINECLLGPHHCVTGERCINTLGSYRCQREISCGTGYELTDNNKCKDIDECDLGTHNCAAEMECQNTAGSFRCRPRMQCAAGFIQDALGSCIDINECVSVTALS-RGQMCFNTVGSFICQRHSVTCGRGYHLNAEGTRCVDIDECAGPDNSC-DGHGCINLVGSYRCECRTGFIFNSISRSCEDIDECRNYPGRLCAHKCENILGSYKCSCTAGFKLADDGRNCDDVNECESSPCSQGCANVYGSYQSYCRRGYQLSDADGITCEDIDECALPTGGHICSYRCHNTPGSFHCTCPASGYTLAANGRSCQDIDECLTGTHSCSESESCFNIQGGFRCLSFDCPANYRRSGDTRPRVDRADIIRCVKSCQHNDISCVLNPILSHSHTAISLPTFREFNKPEEIVFLRSPTPTHLPHMDSPEIVYDILEGNIQNSFDIIKRLDHGMIVGVVKQVRPLVGPVRTVLKLAMNYVTNGVVSHRNIINVRIYVSEFWF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ** * .* * * . : :: ** :*:: . . :*** *. :**. **:****** **: *::**.:*.: . * : . .:: *: * **.**:** . : .. . . . * .::***. : . : : .. : :*:**..* * *:* : ***: *::* :** ***:***: *.* * ** ****:**:****: *********::*.*******: * *** .:: **** *******::** :********.*******:*::* . *: *:** **: **:: .******** *******:***: * :.* .** *:* **:****::*: *:.*** * *::**:.******.***** **: ***:.**:*: ***.*:*:*** .***** *********.**********.**:********************* * ****:*:**:*** **.***.*******:** *.** .*:******.****:*:** *****. * : :::* :**:***: .* :*: :*: : ***.*********.:****:***: ** : ...:*::** ***:::******* .** ****:****:***. :**** **** .*******::**:*:***:**", "identical_positions": 376, "similar_positions": 168, "identity": "52.88%" }, { "cls_id": "homologset.agr.RGD:1308668", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q96FE5-1", "uniprot_id": "LIGO1_HUMAN", "id": "Q96FE5-1", "name": "Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1", "aln": "---MQVSKRMLAGGVRSMPSPLLACWQPILLLVLGSVLSGSATGCPPRCECSAQDRAVLCHRKRFVAVPEGIPTETRLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEISHWPYLDTMTPNCLYGLNLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPISTIEGSMLHELLRLQEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGNLETLILDSNPLACDCRLLWVFRRRWRLNFNRQQPTCATPEFVQGKEFKDFPDVLLPNYFTCRRARIRDRKAQQVFVDEGHTVQFVCRADGDPPPAILWLSPRKHLVSAKSNGRLTVFPDGTLEVRYAQVQDNGTYLCIAANAGGNDSMPAHLHVRSYSPDWPHQPNKTFAFISNQPGEGEANSTRATVPFPFDIKTLIIATTMGFISFLGVVLFCLVLLFLWSRGKGNTKHNIEIEYVPRKSDAGISSADAPRKFNMKMI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I5ZPI2-1", "uniprot_id": "A0A8I5ZPI2_RAT", "id": "A0A8I5ZPI2-1", "name": "", "aln": "---------MLAGGMRSMPSPLLACWQPILLLVLGSVLSGSATGCPPRCECSAQDRAVLCHRKRFVAVPEGIPTETRLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEISHWPYLDTMTPNCLYGLNLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPIGTIEGSMLHELLRLQEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLEESAFHSVGNLETLILDSNPLACDCRLLWVFRRRWRLNFNRQQPTCATPEFVQGKEFKDFPDVLLPNYFTCRRAHIRDRKAQQVFVDEGHTVQFVCRADGDPPPAILWLSPRKHLVSAKSNGRLTVFPDGTLEVRYAQVQDNGTYLCIAANAGGNDSMPAHLHVRSYSPDWPHQPNKTFAFISNQPGEGEANSTRATVPFPFDIKTLIIATTMGFISFLGVVLFCLVLLFLWSRGKGNTKHNIEIEYVPRKSDAGISSADAPRKFNMKMI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D1T0-1", "uniprot_id": "LIGO1_MOUSE", "id": "Q9D1T0-1", "name": "Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1", "aln": "---------MLAGGMRSMPSPLLACWQPILLLVLGSVLSGSATGCPPRCECSAQDRAVLCHRKRFVAVPEGIPTETRLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEISHWPYLDTMTPNCLYGLNLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPIGTIEGSMLHELLRLQEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLEESAFHSVGNLETLILDSNPLACDCRLLWVFRRRWRLNFNRQQPTCATPEFVQGKEFKDFPDVLLPNYFTCRRAHIRDRKAQQVFVDEGHTVQFVCRADGDPPPAILWLSPRKHLVSAKSNGRLTVFPDGTLEVRYAQVQDNGTYLCIAANAGGNDSMPAHLHVRSYSPDWPHQPNKTFAFISNQPGEGEANSTRATVPFPFDIKTLIIATTMGFISFLGVVLFCLVLLFLWSRGKGNTKHNIEIEYVPRKSDAGISSADAPRKFNMKMI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q66HV9-1", "uniprot_id": "LIG1B_DANRE", "id": "Q66HV9-1", "name": "Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1-B", "aln": "MTFLQVTIKMVAR-EASGHSYLVACWQPILILMLGTVLSGSATGCPSRCECSAQERSVVCHRRKLITLPEGIPIDTRLLDLSKNRLKAINPEEFLNYPQLEDLQLNENIISVIEPGAFSNLLGLRTLGLRNNNLKLIQLGVFTGLSNLTRLDISENKIVILLDYMFQELYNLKELEVGDNDLVFISHRAFHGLSSLEQLTMERCNLTSVPTEAFSHLHNLLTLKLRHLNVNVIRDFSFRRLYRLKILEIANWPLLESLTAKSLHGLNITTLSITNCNLTAVPYVAIQHLVYLRFFNLSFNPIEVVEGNKMHNLLRLQAFHLVGGRLVSIEPYSFKGLNYLRVLNVSSNSLSTLEESAFHSVGNLETLALHDNPLACDCRLLWVFRRRWRLNFNRQQPSCETPEFLQGKEFKDFPDVLPPNYFTCQKSKIRDHKAIHRFVDEGTTVQFPCQADGDPTPMIMWQSPKKQFITTKSIGRLSVSLDGTLEVRYAQIQDNGTYTCFAVNAGGNDTRLAHLHVHSYSPNWPHQPNKTFAFILNQPSDNSANGTGAMDPFPFDMKTLIIATTMGFISFLGVVLFCLVLLFLWSRGKGNAKPNIEIEYVPRKVDGENSPNEGSHKISMKMI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:* * * *:*******:*:**:**********.*******:*:*:***::::::***** :******.***:*::* :** .:*:**:*:*****:*.:*****.**:.*******.*.**** ***********:*****************:*****.*********:****** **.******:*:*****:****:****.*:.*:*****:*.***:**:******:***::** *:::*.:.*:***:*:****:********:*::*******:***:*** .:**. :*:***** ::****:*. :***:*:***********.*.*:*****.********** *..**************************:* ****:************ ******::::***:** : ***** **** *:*****.* *:* **:*:::::** ***:* **********:****** *:*.******: *****:****:************ ***.:..**.* * *****:**********************************:* ********** *. *. :..:*:.****", "identical_positions": 447, "similar_positions": 126, "identity": "71.75%" }, { "cls_id": "homologset.agr.RGD:1308669", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q498D1-1", "uniprot_id": "FOXP1_RAT", "id": "Q498D1-1", "name": "Forkhead box protein P1", "aln": "MMQESGSEAKSNGSTIQNGSSGGNHLLECGTLRDTRSNGEAPAVDLGAADLAHVQQQQQQALQVARQLLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQVSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQVLLQQQQALMLQQQQLQEFYKKQQEQLQLQLLQQQHAGKQPKEQQQQQVATQQLAFQQQLLQMQQLQQQHLLSLQRQGLLTIQPGQPALPLQPLAQGMIPTELQQLWKEVTSAHTAEETTGSN--HSSLDLTSTCVSSSAPSKTSLIMNPHASTNGQLSVHTPKRESLSHEEH-PHSHPLYGHGVCKWPGCEAVCDDFPAFLKHLNSEHALDDRSTAQCRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKAAPQPLNLVSS-----VTLSKSASEASP-QSLPHTPTTPTAPLTPVTQGPSVITTTSMHTVGPIRR--RYSDKYNVPISSADIAQNQEFYKNAEVRPPFTYASLIRQAILESPEKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEFQKRRPQKISGNPSLIKNMQSGHAYCTPLNAALQASMAENSIPLYTTASMGNPTLGSLASAIREELNGAMEHTNSNESDSSPGRSPMQAVHPIHVKEEPLDPEEAEGPLSLVTTANHSPDFDHDRDYEDEPVNEDME", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P58462-1", "uniprot_id": "FOXP1_MOUSE", "id": "P58462-1", "name": "Forkhead box protein P1", "aln": "MMQESGSETKSNGSAIQNGSSGGNHLLECGALRDTRSNGEAPAVDLGAADLAHVQQQQQQALQVARQLLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ--VSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQVLLQQQQALMLQQQ-LQEFYKKQQEQLQLQLLQQQHAGKQPKEQQ---VATQQLAFQQQLLQMQQLQQQHLLSLQRQGLLTIQPGQPALPLQPLAQGMIPTELQQLWKEVTSAHTAEETTSSN--HSSLDLTSTCVSSSAPSKSSLIMNPHASTNGQLSVHTPKRESLSHEEH-PHSHPLYGHGVCKWPGCEAVCDDFPAFLKHLNSEHALDDRSTAQCRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKAAPQPLNLVSS-----VTLSKSASEASP-QSLPHTPTTPTAPLTPVTQGPSVITTTSMHTVGPIRR--RYSDKYNVPISSADIAQNQEFYKNAEVRPPFTYASLIRQAILESPEKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEFQKRRPQKISGNPSLIKNMQSSHAYCTPLNAALQASMAENSIPLYTTASMGNPTLGSLASAIREELNGAMEHTNSNESDSSPGRSPMQAVHPIHVKEEPLDPEEAEGPLSLVTTANHSPDFDHDRDYEDEPVNEDME", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H334-1", "uniprot_id": "FOXP1_HUMAN", "id": "Q9H334-1", "name": "Forkhead box protein P1", "aln": "MMQESGTETKSNGSAIQNGSGGSNHLLECGGLREGRSNGETPAVDIGAADLAHAQQQQQQALQVARQLLLQQQQQQQ--------------------------------VSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQVLLQQQQALMLQQQQLQEFYKKQQEQLQLQLLQQQHAGKQPKEQQQ--VATQQLAFQQQLLQMQQLQQQHLLSLQRQGLLTIQPGQPALPLQPLAQGMIPTELQQLWKEVTSAHTAEETTGNN--HSSLDLTTTCVSSSAPSKTSLIMNPHASTNGQLSVHTPKRESLSHEEH-PHSHPLYGHGVCKWPGCEAVCEDFQSFLKHLNSEHALDDRSTAQCRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKAAPQPLNLVSS-----VTLSKSASEASP-QSLPHTPTTPTAPLTPVTQGPSVITTTSMHTVGPIRR--RYSDKYNVPISSADIAQNQEFYKNAEVRPPFTYASLIRQAILESPEKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEFQKRRPQKISGNPSLIKNMQSSHAYCTPLNAALQASMAENSIPLYTTASMGNPTLGNLASAIREELNGAMEHTNSNESDSSPGRSPMQAVHPVHVKEEPLDPEEAEGPLSLVTTANHSPDFDHDRDYEDEPVNEDME", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q2LE08-1", "uniprot_id": "FXP1B_DANRE", "id": "Q2LE08-1", "name": "Forkhead box protein P1-B", "aln": "MMQESGTEA-ANGTAHQNGAPPS-----VEGHREVRSKSTTPSSDITASDIINFQQH--QALQVARQILLQQQQQSS----------------------------------VHKSPKNNDKQPATQVPVSVAMMTPQVITPQQMQQILQHQVLSPQQLQLLLQQQQALMLQQQ-LQEFYKKQQEQLHLQLIQQQHGSKQ-QSKE---VSAQQLAFQQQLLQVQQLQQQHLLSLQRQGLLSIQPNQ-TLPLHTLTQGMIPAELQQLWKEVTNSHVKEENSVTNNGHRGLDLSS---PSPVPLKN---HNQHGSTNGQYISHSLKREGSTLDDHSPHSHPLYGHGVCKWPGCEAVFEDFQSFLKHLNNEHALDDRSTAQCRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKPTPQPLNLVSN-----VALSKTAPAASPPLSLPQTPTTPTAPLTPLSQTHSVITPTSLHSVGPIRR--RYSDKYNMPIS-PDIVQNKEFYMNAEVRPPFTYASLIRQAILESPEKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDELEFQKRRPQKISGSPALVKNIHTTLGYGPALSAAFQASMAEN-IPLYTTASIGSPTLNSLASVIREEMNGAMDHGNSNGSDSSPGRSPLPAMHHISVKEEPMDPEEHEGPLSLVTTANHSPDFDHHRDYEDDHGTEDML", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4K6N2-1", "uniprot_id": "A0A0B4K6N2_DROME", "id": "A0A0B4K6N2-1", "name": "", "aln": "-----------------------------------------------------------------MHRIHDDEYS--------------------------------------EDAKESDFKSSIQKEISVKSR-HQISIPDICSDAVKNNCFPPTGFLNNSITFASHVVKCS------------------------------------SPASSIDESSTAAQQHESNPHMHIQGQHMMAPVPDLGFYNVP----EFISEQEKLMFSDAERFLRSKDNEVCN-------------------------NDFSYMHDEFAMR-------------KYYHPLFAHGICRWPGCEMDLEDITSFVKHLNTEHGLDDRSTAQARVQMQVVSQLESHLQKERDRLQAMMHHLYLSKQLLSPTKIDRKDVPGREGKFCRSPLTVNSIGRPIRQTNSPSPLNLPMVNSTNLCSIKKRNHDKNTFSINGGLPYMLERAGLDVQQEIHRNREFYKNADVRPPFTYASLIRQAIIDSPDKQLTLNEIYNWFQNTFCYFRRNAATWKNAIRTNLSLHKCFVRYEDDFGSFWMVDDNEFVKRR-HLSRGRPRKYEPSSSPNSCQSGNGVPTDKNPCDNCTQHCTSLPPG--------------ADNPLDSNNPNDLG-RIGCLPYCGSDGLSKASKDYSNMDSG----MIESNSHLTIDEYSTNMYESSANEHNR", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : ::: . :..*..* :.: * :** *: *: .: :::: :.* : : ::: . : ::::. ** :.: : :* * ::: *. : :*. : : ::.:. ::. * * .. :.: : : ***:.**:*:***** :*: :*:****.**.********.*******.*** :* *:::****** **::.. ..: : *.. . :. . .::*:. . *:. :: *: . . :.. .*. * : :* :*:*** **:***************::**:************ . *.************:* ********** *: *:.* **: ** *** : * * : : . . ... : . .:* *: . * :..:: *.* . * * . . : .: . : :: : .* . :: : :. .*. ", "identical_positions": 150, "similar_positions": 169, "identity": "20.78%" }, { "cls_id": "homologset.agr.RGD:1308670", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q3B7U9-1", "uniprot_id": "FKBP8_RAT", "id": "Q3B7U9-1", "name": "Peptidyl-prolyl cis-trans isomerase FKBP8", "aln": "MASWAEPSEPAAQLLCGAPLLEGFEVLDGVDDAE----------EEDDLSGLPPLEDMGQPTVEEAEQPGALAREFLAATEPEPAPAPAPEEWLDILGNGLLRKKTLVPGPTGSSRPLKGQVVTVHLQMSLENGTRVQEEPELAFTLGDCDVIQALDLSVPLMHVGETAMVTADSKYCYGPQGSRSPYIPPHAALCLEVTLKTAEDGPDLEMLSGQERVALANRKRECGNAHYQRADFVLAANSYDLAIKAITSNAKVDMTCEEEEELLQLKVKCLNNLAASQLKLDHYRAALRSCSQVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAELSKLVKKRAAQRSTETALYRKMLGNPSRLPAKCPGKGAWSIPWKWLFGATAVALGGVALSVVIAARN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35465-1", "uniprot_id": "FKBP8_MOUSE", "id": "O35465-1", "name": "Peptidyl-prolyl cis-trans isomerase FKBP8", "aln": "MASWAEPSEPAALRLPGAPLLEGFEVLDGVDDAE----------EEDDLSGLPPLEDMGQPTVEEAEQPGALAREFLAATEPEPAPAPAPEEWLDILGNGLLRMKTLVPGPKGSSRPLKGQVVTVHLQMSLENGTRVQEEPELAFTLGDCDVIQALDLSVPLMDVGETAMVTADSKYCYGPQG-RSPYIPPHAALCLEVTLKTAEDGPDLEMLSGQERVALANRKRECGNAHYQRADFVLAANSYDLAIKAITSNTKVDMTCEEEEELLQLKVKCLNNLAASQLKLDHYRAALRSCSQVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAELSKLVKKRAAQRSTETALYRKMLGNPSRLPAKCPGKGAWSIPWKWLFGATAVALGGVALSVVIAARN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14318-1", "uniprot_id": "FKBP8_HUMAN", "id": "Q14318-1", "name": "Peptidyl-prolyl cis-trans isomerase FKBP8", "aln": "MASCAEPSEPSAPLPAGVPPLEDFEVLDGVEDAEGEEEEEEEEEEEDDLSELPPLEDMGQPPAEEAEQPGALAREFLAAMEPEPAPAPAPEEWLDILGNGLLRKKTLVPGPPGSSRPVKGQVVTVHLQTSLENGTRVQEEPELVFTLGDCDVIQALDLSVPLMDVGETAMVTADSKYCYGPQG-RSPYIPPHAALCLEVTLKTAVDGPDLEMLTGQERVALANRKRECGNAHYQRADFVLAANSYDLAIKAITSSAKVDMTFEEEAQLLQLKVKCLNNLAASQLKLDHYRAALRSCSLVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAELSKLVKKHAAQRSTETALYRKMLGNPSRLPAKCPGKGAWSIPWKWLFGATAVALGGVALSVVIAARN", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** ******:* *.* **.*******:*** ****** **********..**************** *********************** ******* *****:********** **************.*******************.******************* ******************** ********:****************************************.:***** *** :****************************** *******************************************************:***********************************************************", "identical_positions": 373, "similar_positions": 14, "identity": "90.31%" }, { "cls_id": "homologset.agr.RGD:1308671", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q498R1-1", "uniprot_id": "MTRR_RAT", "id": "Q498R1-1", "name": "Methionine synthase reductase", "aln": "MRRFLLLYATQRGQAKAIAEEISEQALSHGFSADLHCVSESEKYDLKTETGPLVMVVSTTGTGDPPDTARKFVKEIHNKTLPTDFFAHLWYGLLGLGDSEYTYFCNGGKVIDKRLQELGAQHFYDTGHADDCVGLELVVEPWIDGLWPALTKHFKSLGGQEDMSDSDTLAQASDAP-LSMAMKPELLHIQSQVELLSLEDVGKRDSELQEQNETNKNQP-SRIEDFDSSLVNSVPPLSQSSLSIPAVSPEYLEVYLQESLGQDENQASVPPSVDPIFQVPISKAVELTTNDAIKTTLLLELDISKVEFSHQPGDSFNVICPNSGSEVEDLLQRLQLADKQAHRVILKIKMDTKKKGASLPQHVPEGSSLQFIFTWCLEIRAVPKKAFLRALSDYTSDATEKRRLQELCSKQGAADYNRFIRDASVCLLDLLLTFPSCQPPLNLLLEHLPKLQPRPYSCASSSLLHPD-KLHFVFNIVELPSNTTAASLRKGVCTGWLATLVAPFLQPNTEVLTADHSDALAPEILISPRATNSFHLPD-DLSAPIIMVGPGTGVAPFVGFLQHREKLQEQHPDGNFGAMWLFFGCRHKDRDYLFREELRHFLKTGVLTHLKVSFSRDAAPEEEEEAPAKYVQDNLQHHSQQVARTLLQENGYIYVCGDAKNMAKDVHDALVEIISKEAGVDKLEAMKTLATLKQEKRYLQDIWS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C1A3-1", "uniprot_id": "MTRR_MOUSE", "id": "Q8C1A3-1", "name": "Methionine synthase reductase", "aln": "MRRFLLLYATQRGQAKAIAEEISEQAVSHGFSADLHCISESEKYDLKTETGPLVMVVSTTGTGDPPDTARKFVKEIHNKTLPTDYFAHLRYGLLGLGDSEYTYFCNGGKVIDKRLQELGAQRFYDTGHADDCVGLELVVEPWIDGLWAALTKHFKSLGGQENMS--DTLSRASDAP-LSTAMKPELLHIQSQVELLRLEDVGERDSELREQNETNRGQQ-GRIEDFDSSLVHSVPPLSQSSLSIPAVPPEYLEVHLQESLGQEENQASVP-SGDPSFQVPISKAIRLTTNDAVKSTLLLELDISKIEFSHQPGDSFNVTCPNSDREVEELLQRLQLADKRAHRVILKIKTDTKKKGAALPAHVPEGRSLQFILTWCLEIRAVPKKAFLRALAEHTSSATEKRRLQELCSKQGAADYNRFIRDASVCLLDLLLTFPSCQPPLSLLLEHLPKLQPRPYSCASSSLRHPD-KLHFVFNIVEFPPSTTAASPRKGVCTGWLATLVAPFLQPNTDVSNADSGDTLAPEIRISPRATNAFHLPE-DPSAPIIMVGPGTGVAPFVGFLQHREKLQEQHPDGKFGAMWLFFGCRHKDRDYLFREELRHFLKTGVLTHLKVSFSRDAAPDGEE-APAKYVQDNLQRHSQQVARTLLQENGYIYVCGDAKNMAKDVNDTLIGIISNEAGVDKLEAMKTLATLKQEKRYLQDIWS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UBK8-2", "uniprot_id": "MTRR_HUMAN", "id": "Q9UBK8-2", "name": "Methionine synthase reductase", "aln": "MRRFLLLYATQQGQAKAIAEEICEQAVVHGFSADLHCISESDKYDLKTETAPLVVVVSTTGTGDPPDTARKFVKEIQNQTLPVDFFAHLRYGLLGLGDSEYTYFCNGGKIIDKRLQELGARHFYDTGHADDCVGLELVVEPWIAGLWPALRKHFRSSRGQEEIS--GALPVASPASSRTDLVKSELLHIESQVELLRFDDSGRKDSEVLKQNAVNSNQSNVVIEDFESSLTRSVPPLSQASLNIPGLPPEYLQVHLQESLGQEESQVSVT-SADPVFQVPISKAVQLTTNDAIKTTLLVELDISNTDFSYQPGDAFSVICPNSDSEVQSLLQRLQLEDKREHCVLLKIKADTKKKGATLPQHIPAGCSLQFIFTWCLEIRAIPKKAFLRALVDYTSDSAEKRRLQELCSKQGAADYSRFVRDACACLLDLLLAFPSCQPPLSLLLEHLPKLQPRPYSCASSSLFHPG-KLHFVFNIVEFLSTATTEVLRKGVCTGWLALLVASVLQPNIHASHEDSGKALAPKISISPRTTNSFHLPD-DPSIPIIMVGPGTGIAPFIGFLQHREKLQEQHPDGNFGAMWLFFGCRHKDRDYLFRKELRHFLKHGILTHLKVSFSRDAPVGEEE-APAKYVQDNIQLHGQQVARILLQENGHIYVCGDAKNMAKDVHDALVQIISKEVGVEKLEAMKTLATLKEEKRYLQDIWS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VEV2-1", "uniprot_id": "Q9VEV2_DROME", "id": "Q9VEV2-1", "name": "Methionine synthase reductase", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDLGAYKLSEYIPAKPLVGNLELCFTDEEQRPTETCGQLKCCDILKFPFARPDFQPSSVEIKESK----------------------VLVSADKATETKRVVELTLES-TFDYQPGDTIGILPANKLEQVESLLHRLELLDQADTTCHLKLVFNCANKNAKLPAHIPATTTPREILTHCLSLNFVPQKQLLSALAGFTSDDKERCFLSCLSSKQATEYYQSLILEQGLLFIDILEVCVNCRPPLAFLAEHLPRLLPRPYSIANSPLEASNRELRVIYSLLSLKPGVTTS---------------------MLEAAAQQSSPEHSKKVVIYPRMSNLFRYTERDVGRNQILIAVGTGLAPFLGFLAHKEELIKQQPQQPSGQSWLYIGAKTP-EAVLKREKLMEWQESSLLERLRMCYSRGESP--------SYVQHMLEEDCEDLVEFLMKSETVLYICADGAKISQSIAGVLSRCLQKAMHLTEEEASQLLKKLRKQDKYREDVWL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: . : ** : . :: : . . . *.:* *:: :: . .: : ::::.* ::. ::** :.. *.:****::.: .*. :*:.**:**:* *: **: : :*.* ** *:* : : *:* **.:. :*:* :* ** .**. *: *. *.***.: *. :: : ::*:* . .*:*** :* ****:* ***** *.*.* .. :*:.::.::.: . .*: .. : . : :: * ** :* *: .: * . *::. ***:***:*** *:*:* :*:*: * **::*.: . * *::* .: : .:* :*::.:**. . .***. :: . :::.. *::.: :*:*.*. ::::.: ..* :.: : : ** : * .*:::.:* :*:* ", "identical_positions": 116, "similar_positions": 180, "identity": "16.48%" }, { "cls_id": "homologset.agr.RGD:1308673", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q61183-1", "uniprot_id": "PAPOA_MOUSE", "id": "Q61183-1", "name": "Poly(A) polymerase alpha", "aln": "--MPFPVTTQGSQQTQ------PPQRHYGITSPISLAAPKETDCLLTQKLIETLKPFGVFEEEEELQRRILILGKLNNLVKEWIREISESKNLPQSVIENVGGKIFTFGSYRLGVHTKGADIDALCVAPRHVDRSDFFTSFYDKLKLQEEVKDLRAVEEAFVPVIKLCFDGIEIDILFARLALQTIPEDLDLRDDSLLKNLDIRCIRSLNGCRVTDEILHLVPNIDNFRLTLRAIKLWAKRHNIYSNILGFLGGVSWAMLVARTCQLYPNAIASTLVHKFFLVFSKWEWPNPVLLKQPEECNLNLPVWDPRVNPSDRYHLMPIITPAYPQQNSTYNVSVSTRMVMVEEFKQGLAITDEILLSKAEWSKLFEAPNFFQKYKHYIVLLASAP-TEKQRLEWVGLVESKIRILVGSLEKNEFITLAHVNPQSFPAPK--------ESPDREE----------------FRTMWVIGLVFKKTENSENLSVDLTYDIQSFTDTVYRQAINSKMFELDMKIAAMHVKRKQLHQLLPSHVLQK-RKKHSTE----------------------------------------GVKLTALNDSSLDLSMDSDNSMSVPSPTSAMKTSPLNSSGSSQGRNSPAPAVTAASVTSIQASEVSVPQANSSESPGG--PSSESIPQTATQPAISPPPKPTVSRVVSSTRLVNPSPRPSG------NTATKVPNPIVGVKRTSSPNKEESPKKTKTEEDETSEDANCLALSGHDKTETKEQVDLETSAVQSETVP------------ASASLLASQKTSSTDLSDIPALPANPIPVIKNSIKLRLNR--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6G751-1", "uniprot_id": "A0A8I6G751_RAT", "id": "A0A8I6G751-1", "name": "Poly(A) polymerase", "aln": "--MPFPVTTQGSQQTQ------PPQRHYGITSPISLAAPKETDCLLTQKLIETLKPFGVFEEEEELQRRILILGKLNNLVKEWIREISESKNLPQSVIENVGGKIFTFGSYRLGVHTKGADIDALCVAPRHVDRSDFFTSFYDKLKLQEEVKDLRAVEEAFVPVIKLCFDGIEIDILFARLALQTIPEDLDLRDDSLLKNLDIRCIRSLNGCRVTDEILHLVPNIDNFRLTLRAIKLWAKRHNIYSNILGFLGGVSWAMLVARTCQLYPNAIASTLVHKFFLVFSKWEWPNPVLLKQPEECNLNLPVWDPRVNPSDRYHLMPIITPAYPQQNSTYNVSVSTRMVMVEEFKQGLAITDEILLSKAEWSKLFEAPNFFQKYKHYIVLLASAP-TEKQRLEWVGLVESKIRILVGSLEKNEFITLAHVNPQSFPAPK--------ESPDREE----------------FRTMWVIGLVFKKTENSENLSVDLTYDIQSFTDTVYRQAINSKMFELDMKIAAMHVKRKQLHQLLPSHVLQK-RKKHSTE----------------------------------------GVKLAALNDSSLDLSMDSDNSMSVPSPTSAMKTSPLNSSGSSQGRNSPAPAVTAASVTSIQASEVSVPQANSSESPGG--PSSESIPQTATQPAISPPPKPTVSRVVSSTRLVNPSPRPSG------NAATKVPNPIVGVKRTSSPHKEESPKKTKTEEDETSEDANCLALSGHDKTETKEQVGMETSAAPSEAAP------------ASASLVASQKTSSTDLSDIPALPANPIPVIKNSIKLRLNR--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P51003-1", "uniprot_id": "PAPOA_HUMAN", "id": "P51003-1", "name": "Poly(A) polymerase alpha", "aln": "--MPFPVTTQGSQQTQ------PPQKHYGITSPISLAAPKETDCVLTQKLIETLKPFGVFEEEEELQRRILILGKLNNLVKEWIREISESKNLPQSVIENVGGKIFTFGSYRLGVHTKGADIDALCVAPRHVDRSDFFTSFYDKLKLQEEVKDLRAVEEAFVPVIKLCFDGIEIDILFARLALQTIPEDLDLRDDSLLKNLDIRCIRSLNGCRVTDEILHLVPNIDNFRLTLRAIKLWAKRHNIYSNILGFLGGVSWAMLVARTCQLYPNAIASTLVHKFFLVFSKWEWPNPVLLKQPEECNLNLPVWDPRVNPSDRYHLMPIITPAYPQQNSTYNVSVSTRMVMVEEFKQGLAITDEILLSKAEWSKLFEAPNFFQKYKHYIVLLASAP-TEKQRLEWVGLVESKIRILVGSLEKNEFITLAHVNPQSFPAPK--------ENPDKEE----------------FRTMWVIGLVFKKTENSENLSVDLTYDIQSFTDTVYRQAINSKMFEVDMKIAAMHVKRKQLHQLLPNHVLQK-KKKHSTE----------------------------------------GVKLTALNDSSLDLSMDSDNSMSVPSPTSATKTSPLNSSGSSQGRNSPAPAVTAASVTNIQATEVSVPQVNSSESSGG--TSSESIPQTATQPAISPPPKPTVSRVVSSTRLVNPPPRSSGNAATSGNAATKIPTPIVGVKRTSSPHKEESPKKTKTEEDETSEDANCLALSGHDKTEAKEQLDTETSTTQSETIQ------------TAASLLASQKTSSTDLSDIPALPANPIPVIKNSIKLRLNR--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B770-1", "uniprot_id": "A0A8M2B770_DANRE", "id": "A0A8M2B770-1", "name": "Poly(A) polymerase", "aln": "--MPFPITSQ-VQTAQ------PTPKHYGITSPISLAPPKEADLVLTRKLTETLRPFGVFEEELELQRRILVLGKLNTLVKFWIREVSEAKNIPASVIDSVGGKIFTFGSYRLGVHTKGADIDALCVAPRHVERTDFFSSFYEKLKEQEEVKDLRAVEEAFVPVIKLAFDGIEIDILFARLALQTIPENLDLRDDGLLKNLDIRCIRSLNGCRVTDEILHLVPNIENFRLTLRAIKLWAKRHNIYSNILGFLGGVSWAMLVARTCQLYPNAVAATLVHKFFLVFSKWEWPNPVLLKQPEDCNLNLPVWDPRVTPSDRYHLMPIITPAYPQQNSTYNVSASTRAIMVEEFKRGLAITDEILQNKADWSKLFEAPNFFQKYKHYIVLLASAQ-TEKQHLEWVGLVESKIRILVGNLEKNEFITLAHVNPQSFPGPK--------EGNDKEE----------------FSTMWVIGIVFKKMEGSENLNVDLTFDIQSFTDTVYRQAITSKMFEQDMKITAMHVKRKQLHQLLPEVAIHRSKRKHSSD----------------------------------------GVR--AMNDSNLDLSLDSDNSMSVPSPTGPS-AAKIARAPSPQGSTG-----TATNTSELQGKTEATGENTHLASVDG--TSS----SNASGKEAAPP--QSTSPIQSEKKPSEQNPLPSP-------CLSAEP----AVKRPASALENEMTKKAKVEDLSAPEAKSSGETDGHVAPAQIVEVIPSDGELKTETELMVED--------TAEKVPLAQKTSNADLSDVPVLPNNPIPVVKNSIKLRLSR--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KG96-1", "uniprot_id": "A0A0B4KG96_DROME", "id": "A0A0B4KG96-1", "name": "polynucleotide adenylyltransferase", "aln": "MWNSEPTHRQHHQHNGNSTSGGPPAKQLGMTSAISLAEPRPEDLQRTDELRGSLEPYNVFESQDELNHRMEILAKLNTLVKQWVKEISVSKNMPESAAEKLGGKIYTFGSYRLGVHHKGADIDALCVAPRNIERTDYFQSFFEVLKKQPEVTECRSVEEAFVPVIKMNFDGIEIDLLFARLSLKEIPDDFDLRDDNLLRNLDHRSVRSLNGCRVTDEILALVPNIENFRLALRTIKLWAKKHGIYSNSLGYFGGVTWAMLVARTCQLYPNAAAATLVHKFFLVFSRWKWPNPVLLKHPDNVNLRFQVWDPRVNASDRYHLMPIITPAYPQQNSTFNVSESTKKVILTEFNRGMNITDEIMLGRIPWERLFEAPSFFYRYRHFIVLLVNSQ-TADDHLEWCGLVESKVRLLIGNLERNPHIALAHVNPKCFEFKKGQSANNSQNNSGNEDDLKQSQGNQSAVTSAPFCSMWFIGLEFER---SENLNVDLTESIQNFTEHVMMHGVNIKMLKEGMTIDARHVKRKQLSLYLDSDFLKRERKSMESHNNFNNTLLANRKRLSTELAQSQDPLPPGQQPSSGNRGRDSGAKIQRLSDSLTEENSNASSDMGAGTPTTPTTAQLSAPSFKSSGKNGSEIDVVEQEPTQPHNNGNASSNTTTTEVACSXQPPTLHPHPPHQQPPPAPPQPPAHHHHHQKFRKNNNAAAAAASN----SIFNQRSILHAASSLSAALSITGHKRKQQTATSTTMISSSNIAHSNYTQHSTHNNNGGGGGSHYNKTYYIDDDDEDNNQPLLTPNNQTQQQQKAVRITATSASPATSVPVAASAAPPAPTISL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P29468-1", "uniprot_id": "PAP_YEAST", "id": "P29468-1", "name": "Poly(A) polymerase", "aln": "------------MSSQ---------KVFGITGPVSTVGATAAENKLNDSLIQELKKEGSFETEQETANRVQVLKILQELAQRFVYEVSKKKNMSDGMARDAGGKIFTYGSYRLGVHGPGSDIDTLVVVPKHVTREDFFTVFDSLLRERKELDEIAPVPDAFVPIIKIKFSGISIDLICARLDQPQVPLSLTLSDKNLLRNLDEKDLRALNGTRVTDEILELVPKPNVFRIALRAIKLWAQRRAVYANIFGFPGGVAWAMLVARICQLYPNACSAVILNRFFIILSEWNWPQPVILKPIEDGPLQVRVWNPKIYAQDRSHRMPVITPAYPSMCATHNITESTKKVILQEFVRGVQITNDIFSNKKSWANLFEKNDFFFRYKFYLEITAYTRGSDEQHLKWSGLVESKVRLLVMKLEVLAGIKIAHPFTKPFESSY---------CCPTED--------------------------------------DYEMIQDKYGSHKTETALNALKLVTDENKEEESIK---------------------------------------------------------------DAPKAYLSTMYIGLDFNIEN---------------------------------KKEKVDIHIPCTEFVNLCR-----------------------------SFNEDYGDHKVFNLALRFVK-----------------GYDLPDEVFDENEKRPSKKSKRKNLDARHETVKRSKSDAASGDNING--------------------------------TTAAVDVN-------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *:*..:* . . : . .* *. . ** : * .*: :* *: *.: :: *:* **:. . . ****:*:******** *:***:* *.*::: * *:* * . *: : *: : .* :****:**: *.**.**:: *** :* .: * *..**:*** : :*:*** ******* ***: : **::**:*****::: :*:* :*: ***:******* ******* ::.::::**:::*.*:**:**:** :: *.. **:*:: ..** * **:******. :*.*:: **: ::: ** :*: **::*: .: * .*** .** :*:.:: : . : : .::*:* ******:*:*: .** * :** .: * *: * :.: . .:. : . . :* .. :. . : .. . . : : : . : : . . . : : . : . :. ", "identical_positions": 169, "similar_positions": 170, "identity": "20.24%" }, { "cls_id": "homologset.agr.RGD:1308676", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P22071-1", "uniprot_id": "3BHS1_RAT", "id": "P22071-1", "name": "3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1", "aln": "---MPGWSCLVTGAGGFVGQRIIRMLVQEKELQEVRALDKVFRPETKEEFSKLQTKAKVTMLEGDILDAQYLRRACQGISVVIHTAAVIDVSHVLPRQTILDVNLKGTQNILEACVEASVPAFIYCST-----VDVAGPNSYKKIILNGHEE------------EHHESTWSDAYPYSKRMAEKAVLAANGSILKNG-GTLHTCALRPMYIYGERSPFLSVMILAALKNKGILN--VTGKFSIANPVYVGNVAWAHILAARGLRDPKKSQNVQGQFYYISDDTPHQSYDDLNCTLSKEWGLRLDSSWSLPLPLLYWLAFLLETVSFLLRPFYNYRPPFN-CHLVTLSNSKFTFSYKKAQRDLGYVPLVSWEEAKQKTSEWIGTLVEQHRETLDTKSQ-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P24815-1", "uniprot_id": "3BHS1_MOUSE", "id": "P24815-1", "name": "3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1", "aln": "---MAGWSCLVTGAGGFVGQRIIKMLVQEKELQEVRALDKVFRPETKEEFSKLQTKTKVTVLEGDILDAQCLRRACQGISVVIHTAAVIDVTGVIPRQTILDVNLKGTQNLLEACVQASVPAFIFCSS-----VDVAGPNSYKKIVLNGHEE------------QNHESTWSDPYPYSKKMAEKAVLAANGSMLKNG-GTLNTCALRPMYIYGERSPFIFNAIIRALKNKGILC--VTGKFSIANPVYVENVAWAHILAARGLRDPKKSTSIQGQFYYISDDTPHQSYDDLNYTLSKEWGLRPNASWSLPLPLLYWLAFLLETVSFLLRPVYRYRPLFN-RHLITLSNSTFTFSYKKAQRDLGYEPLVNWEEAKQKTSEWIGTIVEQHREILDTKCQ-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P14060-1", "uniprot_id": "3BHS1_HUMAN", "id": "P14060-1", "name": "3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1", "aln": "---MTGWSCLVTGAGGFLGQRIIRLLVKEKELKEIRVLDKAFGPELREEFSKLQNKTKLTVLEGDILDEPFLKRACQDVSVIIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACVQASVPVFIYTSS-----IEVAGPNSYKEIIQNGHEE------------EPLENTWPAPYPHSKKLAEKAVLAANGWNLKNG-GTLYTCALRPMYIYGEGSRFLSASINEALNNNGILS--SVGKFSTVNPVYVGNVAWAHILALRALQDPKKAPSIRGQFYYISDDTPHQSYDNLNYTLSKEFGLRLDSRWSFPLSLMYWIGFLLEIVSFLLRPIYTYRPPFN-RHIVTLSNSVFTFSYKKAQRDLAYKPLYSWEEAKQKTVEWVGSLVDRHKETLKSKTQ-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VVE3-1", "uniprot_id": "Q9VVE3_DROME", "id": "Q9VVE3-1", "name": "3-beta hydroxysteroid dehydrogenase/isomerase domain-containing protein", "aln": "MGNKSGEVLLVTGGSGFLGQHLIKQLLERKEELGIKEIRSLDIVPYKNNIGHEETSLLRTYVADIGGDLKALSPIFNGVDGVFHCAASVKIEYPPNYEELERVNVNGTLAVVDLCIQNNVKRLVYTSCTSVCFVPFKGRSTFSAVINSTESKTDTPTLDSSTLWEQDNQFLIPGYASSKLRAENIVLNSNGAPLHNQKEYLATSAMRAPLTYGECDSHFITEIFDFLSTRGWVFPRIAGVGGKQQLVYAGNVAWGHICAYKALKVSDKAVNGLPVFVTDDTGINDVSRFVQKMAVLGERFKVKTSWWYVPHFLFFFLAFLLEVVVRVAYPYTKYRLRYSLRAIASYTSSMLMYNRLRASIHMDYMPLFDPDASAERSAKWYATWWDQRQQAQKLKKSS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* ****..**:**::*: *::.** :: : . ::::.: :.. * : . * * :.:. ::* *. :.: : : **::** ::: *:: .* ::: * : . * .::. :: . ..: : :. *. ** **: ** :** *:* * *.*:*. *** . .: * *...* : .* . : **. ****.** * :.*: ..*: . * . . . * : :: * : * .* *::::.**** * : * ** :. : : :.* : :. :*. .: * ** . : : ::: :* .: ::::: . * . ", "identical_positions": 80, "similar_positions": 132, "identity": "20.1%" }, { "cls_id": "homologset.agr.RGD:1308677", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZUX1-1", "uniprot_id": "D3ZUX1_RAT", "id": "D3ZUX1-1", "name": "Hydroxylysine kinase", "aln": "-------------------------------------------------MSSGDDQQSQAFTKPTFTEAQASALVESIFGFKVSKIQPLPSYDDQNFHVHISRSQE----TTDDPVEYVLKISNTKSSQTPDLIEMQNHIIMFLRAAGFPTASVCRTKGDNTISLMSIDSGSEIKSYLVRMLTYLPGRPIAEVATSHQQLYEIGRLAARLDKALEDFHHPKLNLLHRENFIWNLKNVPLLENYMGALSQSRNREIVEQVIQLFKEEVMTKLSHFRECINHGDLNDHNILVDLSKSASGDAVYQVSGILDFGDMSYGYYVFEVAITIMYMMIESTSPIQVGGHVLAGFESVIPLTAVERDALFLLVCARFSQSLVMATYSCQLYPENKEYLMITAKTGWKHLQQMFDMGKKAVEEIWFETAKSYEAGISM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5U5V2-1", "uniprot_id": "HYKK_MOUSE", "id": "Q5U5V2-1", "name": "Hydroxylysine kinase", "aln": "-------------------------------------------------MSSGAGWQSQASAKPVFTEAQASALVESVFGFKVSKIQPLPSYEDQNFRVHIARGKE----TTDDPVEYVLKISNTESSQTPELIEMQNHVIMFLRAAGFPTASVCRTKGDNTISLISIDSGSGVKSYLVRMLTYLPGRPIAEVAISHQQLYEIGRLAAQLDKALEEFHHPKLSLFHRENFIWNLKNVPLLEKYMGALSQSRNREIVEQVIRMFKEEVMTKLSHFRECINHGDLNDHNILVDLSKSASGEGVHQVSGILDFGDMSYGYYVFEVAIVIMYMMIESTNPIQVGGHILAGFESVIPLTAVERQALFLLVCSRFSQSLVMAAYSCQLYPENKEYLMITAKTGWKHLQQLFDMGQKAVEEIWFETAKSYESEISM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A2RU49-1", "uniprot_id": "HYKK_HUMAN", "id": "A2RU49-1", "name": "Hydroxylysine kinase", "aln": "-------------------------------------------------MSSGNYQQSEALSKPTFSEEQASALVESVFGLKVSKVRPLPSYDDQNFHVYVSKTK-------DGPTEYVLKISNTKASKNPDLIEVQNHIIMFLKAAGFPTASVCHTKGDNTASLVSVDSGSEIKSYLVRLLTYLPGRPIAELPVSPQLLYEIGKLAAKLDKTLQRFHHPKLSSLHRENFIWNLKNVPLLEKYLYALGQNRNREIVEHVIHLFKEEVMTKLSHFRECINHGDLNDHNILIESSKSASGNAEYQVSGILDFGDMSYGYYVFEVAITIMYMMIESKSPIQVGGHVLAGFESITPLTAVEKGALFLLVCSRFCQSLVMAAYSCQLYPENKDYLMVTAKTGWKHLQQMFDMGQKAVEEIWFETAKSYESGISM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8WFT6-1", "uniprot_id": "HYKK_DANRE", "id": "A8WFT6-1", "name": "Hydroxylysine kinase", "aln": "-------------------------------------------------MSTKE-------SKPNLSHSQVTDVVKRLYGLTASVVRPLPSYDDQNFYVAPSEGG-----------EFVLKVMNSADSENVAVIELQTQSMNFLHQRGLPAQTALPTLTGQLMSLEEFDCGFGTQIYLVRLLTYLPGTTIAKITCSPQILYDVGKMAATLDTVLLQMEHPNTRVLQRERFIWKLTSIPLLNQYVHVMDGDPVQKIVKGVIEKYQVQVMPKLPLFRECINHGDFNDHNLLVK----PDGPSKYKISGILDFADMSCGYFIFELAITIMYMMIESPTPLDVGGPVVAGWESVFPLNEAERDSLYWLVMCRFCQSLVLARYTVIQQPENEEYLMITSRKGLRHLSRLWELGKDEVERRWFQSAQQFRQI---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VJ68-1", "uniprot_id": "Q9VJ68_DROME", "id": "Q9VJ68-1", "name": "Hydroxylysine kinase", "aln": "MEQWNNVELTNMSKKSYTLNHAYDAAEKLNKENTAKSSNGNGTSADESTAADGDLLKPGSDVRPKVEPEDVESLLRRLYGITISEVKEIVAYDDRNFFVKEDSNVKNPLIVTHCPHGYVLKILNSLDSKKEDFVDAQNQMLLYLGKHSVKCPRPVANATGKYYSVERLNG----NSNVVRLLEFIPGEIFHQVPVTKHLLYRSGEYLARLDRALKNFTH---QAYESHKTLWMLQSVPELRQFLYVVKDQEQRLICDEVIDAFEAKVLSQLPSMEHQIIHGDFNEQNIVVEQ---VPNQTEYTIKGVIDFGDTSKSPLIFEIGIALTYMILQAN-DLANGGIFLSGYTSLNPIENSELALLKYCVTARFVQSLVMGLYTHTLHPTN-EYLLVTQEKGWKLLQKLWRESFDDIDELWASTGHQYLTQSNK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :* . :. ::. ::*:. * :: : :*:*:** * :***: *: *:. .:: *.: : :* .. . .: *: .: : :**:* ::** : ::. : : ** *. * ** .* : * . .. :* * .:* *.::: .: . : * . ** :: :*:.:*. :.. * ***:*::*:::. . : :.*::**.* * . :**:.*.: **:::: : ** .::*: *: *: * * * .** ****:. *: * * :**::* ..* : *.::: . . ::. * .:.:.: ", "identical_positions": 77, "similar_positions": 133, "identity": "17.95%" }, { "cls_id": "homologset.agr.RGD:1308678", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A096UWG8-1", "uniprot_id": "A0A096UWG8_RAT", "id": "A0A096UWG8-1", "name": "Poly(A)-specific ribonuclease PNLDC1", "aln": "MDVGADEFEQSLPFLQELVAGADFVGLDIEFTGLRSNLSRPQQISLFDLPSEWYLKTRQSVQQFTICQIGLSMFSSVEGESNKYVAHSCNFFLFPTTFGILDSEFSFQASSVQFLNQYGFDYNKFLKNGIPYMNEEQEKKIKHSILRGNWRVRSSLDKDQIKVVIDKVTQWLDLAEEGDQMTLPGISGFQAFEVQLVLRQALPNIWTVLKEEGVIVKKVSQPHRWYLEHASCDQVTCWKEQILLSARGFSVFFQMLVKAQKQPLVGHNMMTDLLHLHEKFFRPLPESYDQFKQNIHSLFPVLIDTKNVTKDIWKELRFPRVSNLSEVYEVLSSNLNPTKNSGPVIIHARQCKKYAETKCPHEAAYDAFLCGSVLLKVAHLLLQRVHG-GAVHEPAFPQYLDVLAPYVNQVNLIRAGVPKINFSGPDYPSIRPPVLILTVKRWPGVSEHQVYREFQNLCKFDVRRFTRSQFLLLTNKFKDARSVLKEYRSHPTLQVSLYRYWRHSPNITCLLQVCSIVTTWSMIAFLLGRPSP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B2RXZ1-1", "uniprot_id": "PNDC1_MOUSE", "id": "B2RXZ1-1", "name": "Poly(A)-specific ribonuclease PNLDC1", "aln": "MDVGADEFEQSLPLLQELVAGADFVGLDIEFTGLRSNLSRPQQISLFDLPSEWYLKTRQSVQQFTICQIGLSMFSSIEGESNKYVAHSCNFFLFPTTFGILDSEFSFQASSVQFLNQYGFDYNKFLKNGIPYMNEEQEKKIKHSILRGNWRVRSSLDKDQIKVVIDKVTQWLDLAEEGDQMTLPGIAGFQAFEVQLVLRQALPNIWTVLKEEWVIVKKVSQPQRWYLEHASCDQVSCWKEQILLSARGFSVFFQMLVKAQK-PLVGHNMMMDLLHLHEKFFRPLPESYDQFKQNIHSLFPVLIDTKNVTKDIWKELRFPRVSNLLEVYEVLSSNLNPTKDSGPVIIHARQCKKYAETKCPHEAAYDAFLCGSVLLKVAHLLLQRVHGNGAVHEPAFPQYLDVLAPYVNQVNLIRAGVPKINFSGPDYPSIRPPVLILTVKRWPGVSEQQVYREFQNLCKFDVRRFTRSQFLLLTNKFKDARSVLKEYRNHPTLQVSLYRSWRHSPNITCLLQVCSIVTTWAMIAFLLGRPMP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NA58-1", "uniprot_id": "PNDC1_HUMAN", "id": "Q8NA58-1", "name": "Poly(A)-specific ribonuclease PNLDC1", "aln": "-----------MFCTRGLLFFAFLAGLDIEFTGLRSNLSGPQQISLFDLPSEWYLKTRQSVQQFTVCQIGLSVFSAIEGEANKYIAHSCNFYLFPTTFGILDSEFSFQASSVQFLNQYGFNYNKFLKNGIPYMNEEQEKKIRHDILTGNWRVRSSPDKDQIKVVIDEVTRWLELAKEGDWMTLPGITGFQAFEVQLVLRQALPNIWTVLKDEGVVVKKVSKQHRWYLQNTSCDRESCWKENILLSARGFSVFFQMLVKAQK-PLVGHNMMMDLLHLHEKFFRPLPESYDQFKQNIHSLFPVLIDTKSVTKDIWKEMNFPRVSNLSEVYEVLNSDLNPTKNSGPEIVHASRCEKYVETKCPHEAAYDAFLCGSVLLKVAHLLLQKIYHIDPVPESSFPQYLDVLAPYVNQVNLIRAGVPKINFSGPDYPSIRPPILILSVKRWPGVSEQQVYHKFQNLCKFDVRRLTRSQFLLLTNKFKDARNILKEYRDHPTLCISLYRYWRHSPNVNCLLQVCGIVTAWALLAFILGRSGT", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : *: * :.************** *************************:******:**::***:***:******:****************************:********************:*.** ******** **********:**:**:**:*** ******:***********************:* *:*****: :****:::***: :****:******************** ******** ***********************************.********:.******* ******.*:*****:*** *:** :*:**.****************************::: ..* *.:**************************************:***:*********:***::***********:****************.:*****.**** :**** ******:.******.***:*:::**:***. .", "identical_positions": 429, "similar_positions": 67, "identity": "80.64%" }, { "cls_id": "homologset.agr.RGD:1308679", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XIS1-1", "uniprot_id": "SSH3_RAT", "id": "Q5XIS1-1", "name": "Protein phosphatase Slingshot homolog 3", "aln": "MALVTVSRSPPASGHSTPVGPT-DRVIRRRGRLQRRQSFAVLRGAVLGLQDGGEGNDAAEADPEPMEKPSGEEQPAEDQTDNGQGSQSPWKQVQKR-HLHLMVELLRPQDDIRLAAQLEAARPPRLRYLLVVST--GEGLSEEETILLGVDFPDSSS-----------------------------------------------------------------HSCTLGLVLPLWSDTQVYLDGDGGFSVTSGGQSRIFKPVSIQTMWATLQVLHQACEVALGSGLVPGGSALAWATHYQEKLNSDQGCLNEWMAMSDLESFRPP--NAEPGQASEQEQMEQAILAELWQVLDASDLDSVTSKEIRQALELRLGCPLQQYRDFIDNQMLLLMAQQDRASRIFPHLYLGSEWNAANLEELQRNRVSHILNMAREIDNFFPERFTYHNVRVWDEESAQLLPHWKETHRFIEDARAQGTRVLVHCKMGVSRSAATVLAYAMKQYGWGLEQALIHVQELRPIVRPNPGFLRQLQTYQGILTASRQSHVWEQKVGVVSPEEPLAPEVSTPLPPLPPEPGG-SGEGMVMGQKGSQETPKEELGLRPRINLRGVMRSISLLEPSSEPESTTEAGDLPEVFSSDE---------------------------------------------EPLHPFSQLSRAKGGQRVCKGPWPALKSRQSVVALHSAALVASRARAFQGQGQGQGQEQRETGTSSTPRLRKVIRQASVDDSREEGKA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K330-1", "uniprot_id": "SSH3_MOUSE", "id": "Q8K330-1", "name": "Protein phosphatase Slingshot homolog 3", "aln": "MALVTVSRSPPASGHSTPVGPTQDRVVRRRGRLQRRQSFAVLRGAVLGLQDGGDSNVASEADSEPMEEPSGEEQPTEDQTDKGQGLQSPWKQVQKR-HLHLMVELLRPQDDIRLAAQLEAARPPRLRYLLVVST--GEELS-EEAILLGVDFPDSSS-----------------------------------------------------------------HSCTLGLVLPLWSDTQVYLDGDGGFSVTSGGQSRIFKPVSIQTMWATLQVLHQACEVALGSGLVPGGSALAWATYYQEKLNSDQGCLNEWMAMSDLESFRPP--NAEPGQASEQEKMEQAILAELWQVLDTSDLDSVTSKEIRQALELRLGCPLQQYRDFIDNQMLLLMAQQDRASRIFPHLYLGSEWNAANLEELQKNRVSHILNMAREIDNFFPERFTYYNVRVWDEESAQLLPHWKETHRFIEDARAQGTRVLVHCKMGVSRSAATVLAYAMKQYGWDLEQALIHVQELRPIVRPNHGFLRQLRTYQGILTASRQSHVWEQKVGVVSPEEPLAPEVSTPLPPLPPEPGG-SGEVMVMGLEGSQETPKEELGLRPRINLRGVMRSISLLEPS-ESESTPEAGGLPEVFSSDE---------------------------------------------EPLHPFSQLSRAKGGQRVRKGPWPALKSRQSVVALHSAALVASRTRAFQEQGQGQ--EQSEPGMSSTPRLRKVMRQASVDDSREEDKA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TE77-1", "uniprot_id": "SSH3_HUMAN", "id": "Q8TE77-1", "name": "Protein phosphatase Slingshot homolog 3", "aln": "MALVTVSRSPPGSGASTPVGPW-DQAVQRRSRLQRRQSFAVLRGAVLGLQDGGDNDDAAEASSEPTEKAPSEEELHGDQTDFGQGSQSPQKQEEQRQHLHLMVQLLRPQDDIRLAAQLEAPRPPRLRYLLVVSTREGEGLSQDETVLLGVDFPDSSS-----------------------------------------------------------------PSCTLGLVLPLWSDTQVYLDGDGGFSVTSGGQSRIFKPISIQTMWATLQVLHQACEAALGSGLVPGGSALTWASHYQERLNSEQSCLNEWTAMADLESLRPP--SAEPGGSSEQEQMEQAIRAELWKVLDVSDLESVTSKEIRQALELRLGLPLQQYRDFIDNQMLLLVAQRDRASRIFPHLYLGSEWNAANLEELQRNRVTHILNMAREIDNFYPERFTYHNVRLWDEESAQLLPHWKETHRFIEAARAQGTHVLVHCKMGVSRSAATVLAYAMKQYECSLEQALRHVQELRPIARPNPGFLRQLQIYQGILTASRQSHVWEQKVGGVSPEEHPAPEVSTPFPPLPPEPEG-GGEEKVVGMEESQAAPKEEPGPRPRINLRGVMRSISLLEPSLELESTSETSDMPEVFSSHES-----------------------------------------SHEEPLQPFPQLARTKGGQQVDRGPQPALKSRQSVVTLQGSAVVANRTQAFQEQEQGQGQGQGEPCISSTPRFRKVVRQASVHDSGEEGEA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PUK7-1", "uniprot_id": "A0A8M9PUK7_DANRE", "id": "A0A8M9PUK7-1", "name": "Protein phosphatase Slingshot homolog 1", "aln": "MALLTLHRAP--SICTTP-----DEPIPRRGRLQKRESFALVKGAVLLVEE--------------EEREGLQEETVSPRLGPRHGGQAS--DTQRR-HLHAMISLLRPEDTVKLAVRLESARPVRVRYLLIIGT----LDNKEESLLLGMDFPSLNS-----------------------------------------------------------------DECTIGLVLPIWSDTQVYLDGDGGFSVTSAEVTRIFKPVSIQTMWSVLQALHGCCERAMRGAVIPS-SGLEWAQFYKQNVESDQLCLNEWGAMTGLESVRKD--TGG-RSSSNRESVEREIKAQLRDIMRTEDLENITSKQVRTSLESRIGIDMKDYKEYIDNEMMVTMAQMDKPSRILDYLYLGSEWNAANFEELQKNNVGYILNVTMEIDNFFPECFTYMNIRVYDVEATDLLSHWNNTYMFINEARKSGQAVLVHCKMGVSRSASTVIAFLMKQQGWTLDQALNHVRERRPIVQPNEGFLKQLNTYSGILNASKQRHSALWRR--KSKADARQPSVHN-----EQATGD-ENEEKEEEEEESQ-SPDEE-SSEEDTDVFEQMCEN-VLDTG-EAESATSN-QFLSIQESDK---------------------------------------------------VSSSPSRSGRMDLFSLMQSIQLDDEDRGMDKEMSVCQRLSPGQRRRSQGRRGLTYQRAHVDASPEPSSRQTQHTNNDEAGL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6NN85-1", "uniprot_id": "SSH_DROME", "id": "Q6NN85-1", "name": "Protein phosphatase Slingshot", "aln": "MALVTVQRSPSVAGSCSNSDGESEDDEGNSKGNDRSECFFAGKGTALVLALK-------------DIPPLTQSERRLSTDSTRSSNSTQSNNSDIQLHLQSMFYLLQREDTLKMAVKLESQRSNRTRYLVIASRSCCRSGTSDRRRHRIMRHHSVKVGGSAGTKSSTSPAVPTQRQLSVEQTATEASSKCDKTADKENATAAGDNKNTSGMEESCLLGIDCNERTTIGLVVPILADTTIHLDGDGGFSVKVYEKTHIFKPVSVQAMWSALQTLHKVSKKARENNFYASGPSHDWLSSYERRIESDQSCLNEWNAMDALESRRPPSPDAIRNKPPEKEETESVIKMKLKAIMMSVDLDEVTSKYIRGRLEEILDMDLGEYKSFIDAEMLVILGQMDAPTKIFEHVYLGSEWNASNLEELQKNGVRHILNVTREIDNFFPGTFEYFNVRVYDDEKTNLLKYWDDTFRYITRAKAEGSKVLVHCKMGVSRSASVVIAYAMKAYQWEFQQALEHVKKRRSCIKPNKNFLNQLETYSGMLDAMKNKEKLQRSKSETNLKSTKDARLLPGSEPTPLIQALNQAKSKSTGEAGVTPDGEEEDGSRMHRRSIAQKSQRRMVRRSSSTSPKTQTAVVTKQQSQSMENLTPERSVAEEPKNMRFPGSNGENYSVTQNQVLHIQKHTPLSVRTRIHDLEAHRADQLPQQPVWTSLTKLITQTSHLGKSVSGSSSGNIDSRRDSSCSDVFSSQVDSVFAKDEGEKRQRRKTHSWTESLGPSGGIVLDPTPQQQKQQSNAILRPRGTRQRELPSRHASWGSGDNRCCLPQRTSSGSYYDSNRNTTAIFEGVIQDLKRSSNCNVIEGVAVAVEPIVGVGEGTVKRTKQKLEESTSLKKRCQEESQELLLEAVDAGQRRCPSLYRSASSAHSPRQRQPLRCNSEELMHTSDIENKNTTPGDHEATVVLRVQGQTLADDQRISGNVQILKQNFEAKAGVVGTGGGGGGGTAAGSGSSSTIATSVSAVAGACSANPGKKTTSHQSLPSSPVAQHANHVSAASNSNSSASNSSDSS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:*: *:* : : : . :: :.* :*:.* : :.: . . .: : : : **: *. **: :* :::*.:**: *. * ***:: . . :. : . . . *:***:*: :** ::*********. ::****:*:*:**:.**.** .: * . . .. .. * *:..::*:* ***** ** *** * . ..::*. * * :* :: **:.:*** :* ** :. : :*:.:** :*:: :.* * .::*: ::********:*:****:* * :***:: *****:* * * *:*::* * ::** :*.:*. :* *: .* *************:.*:*: ** ::*** **:: *. :** .**.**. *.*:* * :: . . . . : : .** . . . :: . . .. .. . . .. : : : . . . . : . *: . . . ", "identical_positions": 159, "similar_positions": 177, "identity": "15.03%" }, { "cls_id": "homologset.agr.RGD:1308681", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P62913-1", "uniprot_id": "RL11_HUMAN", "id": "P62913-1", "name": "Large ribosomal subunit protein uL5", "aln": "MAQ-----DQGEKENPMRELRIRKLCLNICVGESGDRLTRAAKVLEQLTGQTPVFSKARYTVRSFGIRRNEKIAVHCTVRGAKAEEILEKGLKVREYELRKNNFSDTGNFGFGIQEHIDLGIKYDPSIGIYGLDFYVVLGRPGFSIADKKRRTGCIGAKHRISKEEAMRWFQQKYDGIILPGK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62914-1", "uniprot_id": "RL11_RAT", "id": "P62914-1", "name": "Large ribosomal subunit protein uL5", "aln": "MAQ-----DQGEKENPMRELRIRKLCLNICVGESGDRLTRAAKVLEQLTGQTPVFSKARYTVRSFGIRRNEKIAVHCTVRGAKAEEILEKGLKVREYELRKNNFSDTGNFGFGIQEHIDLGIKYDPSIGIYGLDFYVVLGRPGFSIADKKRRTGCIGAKHRISKEEAMRWFQQKYDGIILPGK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CXW4-1", "uniprot_id": "RL11_MOUSE", "id": "Q9CXW4-1", "name": "Large ribosomal subunit protein uL5", "aln": "MAQ-----DQGEKENPMRELRIRKLCLNICVGESGDRLTRAAKVLEQLTGQTPVFSKARYTVRSFGIRRNEKIAVHCTVRGAKAEEILEKGLKVREYELRKNNFSDTGNFGFGIQEHIDLGIKYDPSIGIYGLDFYVVLGRPGFSIADKKRRTGCIGAKHRISKEEAMRWFQQKYDGIILPGK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P46222-1", "uniprot_id": "RL11_DROME", "id": "P46222-1", "name": "Large ribosomal subunit protein uL5", "aln": "MAAVTKKIKRDPAKNPMRDLHIRKLCLNICVGESGDRLTRAAKVLEQLTGQQPVFSKARYTVRSFGIRRNEKIAVHCTVRGAKAEEILERGLKVREYELRRENFSSTGNFGFGIQEHIDLGIKYDPSIGIYGLDFYVVLGRPGYNVNHRKRKSGTVGFQHRLTKEDAMKWFQQKYDGIILNTKK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0C0W9-1", "uniprot_id": "RL11A_YEAST", "id": "P0C0W9-1", "name": "Large ribosomal subunit protein uL5A", "aln": "MSA--------KAQNPMRDLKIEKLVLNISVGESGDRLTRASKVLEQLSGQTPVQSKARYTVRTFGIRRNEKIAVHVTVRGPKAEEILERGLKVKEYQLRDRNFSATGNFGFGIDEHIDLGIKYDPSIGIFGMDFYVVMNRPGARVTRRKRCKGTVGNSHKTTKEDTVSWFKQKYDADVLDK--", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q3E757-1", "uniprot_id": "RL11B_YEAST", "id": "Q3E757-1", "name": "Large ribosomal subunit protein uL5B", "aln": "MST--------KAQNPMRDLKIEKLVLNISVGESGDRLTRASKVLEQLSGQTPVQSKARYTVRTFGIRRNEKIAVHVTVRGPKAEEILERGLKVKEYQLRDRNFSATGNFGFGIDEHIDLGIKYDPSIGIFGMDFYVVMNRPGARVTRRKRCKGTVGNSHKTTKEDTVSWFKQKYDADVLDK--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: :****:*:*.** ***.***********:******:** ** ********:************ ****.*******:****:**:** .*** ********:***************:*:*****:.*** : :** .* :* .*: :**::: **:****. :* ", "identical_positions": 121, "similar_positions": 32, "identity": "65.76%" }, { "cls_id": "homologset.agr.RGD:1308682", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A096MKC4-1", "uniprot_id": "A0A096MKC4_RAT", "id": "A0A096MKC4-1", "name": "Transmembrane channel-like protein", "aln": "----------------------------------MLQIQVEGK-----------------------------------------------------------------------------------EDDTDASSSEEEEE-----DKLPRRESLRPKRKRTRDVINEDDPEPEPEDEE-----------TRKAREKERRRRLRR---------------GAEEEEE-----------IDEEELERLKALLDENRQMIATVKCKPWKMEKKIEVLKEAKKFVSENEGALGK------GKGKKWFAFKMMMAKKWAKFLRDFENFKAACVPWENKIKAIESQFGSSVASYFLFLRWMYGVNMVLFILTFSLIMLPEYLWGLPYGSLPRKTVPRAEEASAANFGVLYDFNGLAQYSVLFYGYYDNKRTIGWLNFRLPLSYFLVGIMCIGYSFLVVLKAMTKN-IGDDGGGDDNTFNFSWKVFCSWDYLIGNPETADNKFNSITMNFKEAIIEERAAQVEENIHLIRFLRFLANFFVFLTLGASGYLIFWAVKRSQEFAQQDPDTLGWWEKNEMNMVMSLLGMFCPTLFDLFAELEDYHPLIALKWLLGRIFALLLGNLYVFILALMDEINNKIEEEKLVKAN------------------------------------------------------------------------------------------------------------------------------------------------------ITLWEANMIKAYNESLS---GNTTGPPFFVHP----------------------------------------------------------------------------------------ADVPRGP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CWETMVGQEFVRLTVSDVLTTYVTILIGDFLRACFVRFCNYCWCWDLEYGYPSYTEFDISGNVLALIFNQGMIWMGSFFAPSLPGINILRLHTSMYFQCWAVMCCNVPEARVFKASRSNNFYLGMLLLILFLSTMPVLYMIVSLPPSFDCGPFSGKNRMFEVIGETLEHDFPSWMAKILRQLSNPGLVIAVILVMVLTIYYLNATAKGQKAANLDLKKKMKQQALENKMRNKKMAAARA-----AAAAGGQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R4P5-1", "uniprot_id": "TMC1_MOUSE", "id": "Q8R4P5-1", "name": "Transmembrane channel-like protein 1", "aln": "----------------------------------MLQIQVEEK-----------------------------------------------------------------------------------EEDTEESSSEEEE------DKLPRRESLRPKRKRTRDVINEDDPEPEPEDEE-----------TRKAREKERRRRLRR---------------GAEEEEE-----------IDEEELERLKALLDENRQMIATVKCKPWKMEKKIEVLKEAKKFVSENEGALGK------GKGKKWFAFKMMMAKKWAKFLRDFENFKAACVPWENKIKAIESQFGSSVASYFLFLRWMYGVNMVLFVLTFSLIMLPEYLWGLPYGSLPRKTVPRAEEASAANFGVLYDFNGLAQYSVLFYGYYDNKRTIGWLNFRLPLSYFLVGIMCIGYSFLVVLKAMTKN-IGDDGGGDDNTFNFSWKVFCSWDYLIGNPETADNKFNSITMNFKEAIIEERAAQVEENIHLIRFLRFLANFFVFLTLGASGYLIFWAVKRSQEFAQQDPDTLGWWEKNEMNMVMSLLGMFCPTLFDLFAELEDYHPLIALKWLLGRIFALLLGNLYVFILALMDEINNKIEEEKLVKAN------------------------------------------------------------------------------------------------------------------------------------------------------ITLWEANMIKAYNESLSGLSGNTTGAPFFVHP----------------------------------------------------------------------------------------ADVPRGP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CWETMVGQEFVRLTVSDVLTTYVTILIGDFLRACFVRFCNYCWCWDLEYGYPSYTEFDISGNVLALIFNQGMIWMGSFFAPSLPGINILRLHTSMYFQCWAVMCCNVPEARVFKASRSNNFYLGMLLLILFLSTMPVLYMIVSLPPSFDCGPFSGKNRMFEVIGETLEHDFPSWMAKILRQLSNPGLVIAVILVMVLTIYYLNATAKGQKAANLDLKKKMKQQALENKMRNKKMAAARA-----AAAAGGQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TDI8-1", "uniprot_id": "TMC1_HUMAN", "id": "Q8TDI8-1", "name": "Transmembrane channel-like protein 1", "aln": "------------------------------MSPKKVQIKVEEK-----------------------------------------------------------------------------------EDETEESSSEEEEEVE---DKLPRRESLRPKRKRTRDVINEDDPEPEPEDEE-----------TRKAREKERRRRLKR---------------GAEEEE------------IDEEELERLKAELDEKRQIIATVKCKPWKMEKKIEVLKEAKKFVSENEGALGK------GKGKRWFAFKMMMAKKWAKFLRDFENFKAACVPWENKIKAIESQFGSSVASYFLFLRWMYGVNMVLFILTFSLIMLPEYLWGLPYGSLPRKTVPRAEEASAANFGVLYDFNGLAQYSVLFYGYYDNKRTIGWMNFRLPLSYFLVGIMCIGYSFLVVLKAMTKN-IGDDGGGDDNTFNFSWKVFTSWDYLIGNPETADNKFNSITMNFKEAITEEKAAQVEENVHLIRFLRFLANFFVFLTLGGSGYLIFWAVKRSQEFAQQDPDTLGWWEKNEMNMVMSLLGMFCPTLFDLFAELEDYHPLIALKWLLGRIFALLLGNLYVFILALMDEINNKIEEEKLVKAN------------------------------------------------------------------------------------------------------------------------------------------------------ITLWEANMIKAYNASFS---ENSTGPPFFVHP----------------------------------------------------------------------------------------ADVPRGP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CWETMVGQEFVRLTVSDVLTTYVTILIGDFLRACFVRFCNYCWCWDLEYGYPSYTEFDISGNVLALIFNQGMIWMGSFFAPSLPGINILRLHTSMYFQCWAVMCCNVPEARVFKASRSNNFYLGMLLLILFLSTMPVLYMIVSLPPSFDCGPFSGKNRMFEVIGETLEHDFPSWMAKILRQLSNPGLVIAVILVMVLAIYYLNATAKGQKAANLDLKKKMKMQALENKMRNKKMAAARA-----AAAAGRQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QFU0-1", "uniprot_id": "TMC1_DANRE", "id": "F1QFU0-1", "name": "Transmembrane channel-like protein 1", "aln": "-----------------------MPRHKLIASESDVSIEVDEGKDKESCVYYVEVEENCERGKIKQASRDGKRRRERNGETRRKASEKRTNEGESKKAEKKHEKGHRTARKAGEKHGKRQRRKNAGEEDAEDKSSKEKKNMKNEKNKTLKLEEEKEKDVRKKKRKHVKNEEDETNHEK-----------TKQHLKEEKRRKKRKKPETTSESESKSESESASESESKNSPAVGVLGSLTPEELENLKEAVEERKKLITQLKGKPWPMRRKLVVLRESQEFVEKYEGALGK------GKGRKLYAYKVMMMKKWMKFQRDFENFKTACIPWEMKIKEIESHFGSSVASYFIFLRWMYGINMILFGLTFGLVMVPEALMGKPYGSLPRKTVPREEEASAMNFAVLWDFGGYAKYSVLFYGYYNSQRAIGWLKFRMPLSYFLVGVGTVAYSYMVVIRTMARN-ANEEGGGDDTSFNFSWKTFTSWDYLIGNPETADNKFASITTSFKEAIVEEQESRKDDNIHLTRFLRVLANFLVLCCLAGSGYLIYFVVRRSQKFALEGLENYGWWERNEVNMVMSLLGMFCPMLFDVISTLENYHPRIALQWQLGRIFALFLGNLYTFIIALMDAIQLKRAEEEIVKKN------------------------------------------------------------------------------------------------------------------------------------------------------MTIWQAN---LYNGTVP---DNSTAPPLTVHP----------------------------------------------------------------------------------------ADVPRGP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CWETMVGQEFVRLIISDTMTTYITLLIGDFMRAVLVRFLNNCWCWDLEYGFPSYSEFDVSGNVLGLIFNQGMIWMGAFYAPCLPALNLLRLHVSMYLQCWAVMCCNVPQERVFKASGSNNFYMAMLLVILFLSTLPAIYTIVSIPPSFDCGPFSGKPRMFDVIQETLETDFPAWFSKVFSYASNPGLVLPFLLLLVLAIYYLQSTSKTYKRVNMELKKKLQAQNEENKKKNKLAALKAASDLEQARKAGEQRRNSISDLGVNEENPESHVSSSHT--------------------------SRPPASRGHTSSGHLPGHPQQPQKNSKKR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0U1QT59-1", "uniprot_id": "TMC_DROME", "id": "A0A0U1QT59-1", "name": "Transmembrane channel-like protein", "aln": "MQNDEEPAAAAGTSGLSNGESLRSPPAPAPRRPKPGILRLDIGKPRRSSGGSVDFRCVGSSSSNGNTSNVATGANSENNSGVTSPHQLSVTWAPPCDLDRGGWQMQSSADAKREFYKGQRGRRAASQEDHRSYELNDFPLQNQSSDAESCHQEPHFAHQRSPGIGFDEDGGGGDIDDEESYTISVSAIMQRRASVRGYRGKRGSRSSRRASSPMDHVLDSVERRRSSVYTTSSEEGTNQESTQEQIFENIRLHKEVIQSVKLQPWPIRKKLKLVRQAKTYVARHEGALQERFAMSRSTRDLWARFKILMAARWRHWKRETASFLTVLIPWELRIKEIESHFGSGVASYFTFLRWLMWVNIMIAIPLVAFVIGPEYFATKHGETDPRKRMSDPEARVAGNLFTFWEFEGYLKYSPMFYGYYSSTSGISTSGYKLPLAYFLTAVLVYIYSFVATLRKMAENSRNSKLSSKDDECVFSWKLFTGWDFMIGHAETAHNRIASVVVGFKEALLEEAEKKKDNRNWRVILQRILVNILVMGLLGLSGATVVLLVNHSEDLAKHDN----WLSRNAVNVTMTLLSFFLPMIFEALGLFENWHPRQQLRLQLARIMILNMLNLYSLMFSFIYKINSKEKPLQMLKLENETNTMELKNLLSSIEALRAMTPTTSLYGESTSDGLFDDSTSTATWGEDGGGLFSTTAAAALISTTVQRLKCYNMTVKCSKLRRNIISGKHLATTLMVLNLTTPAMVPPTLPTTLPTTFPTTLPTTLPTTLPTALPTTLPTTLPTTLPSTLATTTATTSSIWSTTEETSPTTTTTSPWTTLPPSTTTTEATTTTERATTTTEATSTTTLKITTAEINSTLSDTTKPLGKSIDTEIPNSTTNSATLSTIPATLNTTNLPLNSTTKLTTTTSTEKPQGEDNFIYTTGEDEGSYDYGSDSTSDAPDNNSYSDITDYSSEPSEIEDFDEQESTDQADDPLAKVLEQLDENETKGRRKRALAESPFFTSKYSRRHRNESAVSAGQPRETTESVNATPSRWPFNWASFRQTTPRTTTTRRVPSGILTKEEWERLRRLRGRITTTTSTSTTSTTTRRPRWRYRTTTTELTSTTEEESSTTESSTDSSSPGSTTNAFDSSSSTTEEDEYTTTEGSENRPYYVGYVDISEMGSTIYYDGDSEFLEECVITICPKGDDFFGSTTESPDSTTQSSDSKQLTTVKLTPLERKQKRLKEVQLAIKQIQTNLTTMCWETSLGQELSKVIVFDGLMSIVAPLCIDFLRALFVRYVNQNWCWDMEKTFPQYGDFKIAENILTLINNQGQVWMGIFFSPGLVLINLVKLMIMMYFRSWIVLTCNVPHEVVFKASKSNNFYLSLLLTMLFLCVLPVGYAIVWLRPSWHCGPFSEYNRIAEFITNTTRNALPKQLHEPLDYLTSSSTVIPLLLLLILIIYYLVSLTGALREANQDLRTQLQKEREEERKKIFKVPEVKQAEPTATTLTNRWRKVLEASSPVTPTQPPDFDTEEYKNQARKELISRIMKKALRKGSATSDEDSFVRRDDDDTDTEHQDSLPHDEEAKDKRFGLSRLQQIRRTRKPSLVDIVQIAKQERARAGSIVAGTSSSGTGNFPIKETHPKSRFKVEKHERKDRGSMKDKKDTRHRQSPQQQQQPPPYESPKDNEHDPDTNSRIVSASLLRRHKEQAEGEEPPTTPDAPQTPNSPVEPVEQALEESTPETPTLAKSKFHIVDEKKPPPHEVEDKPLPTPKESGSGGGSLGKFKFRKHKFKSNNVAAVKPEPEVFKFDERSVERSSDVPATHAAEYLNNEPSGTEEQDRSLPSPTPSQGQGHHQRQLSVLSRQGRKKIGNLLALVREAVNLKKDDVEQAGSDESPGPTTPTYLAYTPPPPPSVLSSVSSSTALEMPPTPEPESPTPSAPLHFGSSTSSRAPSKPPKPPMVPASATAPTATMDDLEELDTAGPITFPRRSDSHRRRTMRQDSQSSIWSDNIPTITISTTGSDECIVDAAAPQNGLPDPRSASPEPTVNIIRIDIENEHEK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.:: ::: . :: : :. : *. .: .:: :: . * : .... . . *.: : .:::* :* :** :.:*: :::::: :* . **** : .. :*::* :* :: *: .* :. :*** :** ***:***.***** ****: :*::: ..::: ** : : *** :. * * *: .:::* * :** :*****.. *. :::**:***..: **::..:: *:.* ... ...* **** * .**::**:.***.*:: *:. .****: ** : ::. : *.*.*::*: *. ** : *.:*:.:* .. * .:* :*:.*:**.:* * :*: :. :*::** *: *.**: * : *** :::::: *: * :::* : :: *. :. : .:* .* . * :: *:* **** :***: :: : * : : :: * **:** :**: * ****:* :*.* :*.:: *:* ** *** :*** *::* * :*:::* **::.* *: ****. ***** *****:.:** :***..:*. * ** : **:.***** *: :.* :* . :* : : : :... *:..:*:::* **** : : : .* :*:.::: : *:: : . : :. ", "identical_positions": 213, "similar_positions": 268, "identity": "10.44%" }, { "cls_id": "homologset.agr.RGD:1308683", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0U1RRY7-1", "uniprot_id": "A0A0U1RRY7_RAT", "id": "A0A0U1RRY7-1", "name": "Max-binding protein MNT", "aln": "----MSIETLLEAARFLEWQAQQ--------------------QQRAREEQERLRLEREREREQEQKRASNLARLAHALPVE-------------------------------------------------------------------------------------EPRVEAPPLPLSPPAPPPAPPPPLATPAPLTVIPIPVVTNSPQSLP----PPP-------PLPPAAQPLPLAPRQPALVSTPGLSIKEPVPLPTRPQVPTPAPLLPDSK---------------------------------TTVAPTGSPKPLQPLPTPILTIAPHPGVQPQLAPQQPPPPTLGTLKLAPAEEAKSSEQKKRPG--------------------------------------------------------------------------------GIGTREVHNKLEKNRRAHLKECFETLKRNIPNVDD--KKTSNLSVLRTALRYIQSLKRKEKEYEHEMERLAREKIATQQRLAELKHELSQWMDVLEIDRVLRQTGQPEDDQASTSTASEGEDNVDEEMEGDRAGLGPPKLNHRPQPELLKAALPTPSTAPAPLPAHPHPHPHPVALSPAHLPVQQQ-PPQQKTPLPAPPP--PPATPTQTLVPAPAHLVATAGGGSTVIAHT-ATTHASVIQTVNHVLQGPGGKHIAHIAPSAPSPAVQLAPATPPIGHITVHPATLNHVAHLGSQLPLYPQPVAVSQPVAVSHIAHTLSHQQVNGTAGLGPPATVMAKP-AVGAQVV-HHPQLVGQTVLNPVTMVTMPSFPVSTLKLA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08789-1", "uniprot_id": "MNT_MOUSE", "id": "O08789-1", "name": "Max-binding protein MNT", "aln": "----MSIETLLEAARFLEWQAQQ--------------------QQRAREEQERLRLEREREREQEQKRASNLARLAHALPVE-------------------------------------------------------------------------------------EPRIEAPPLPLSPPAPPPAPPPPLATPAPLTVIPIPVVTNSPQSLP----PPP-------PLPPAAQPLPLAPRQPALVSTPGLSIKEPVTLPTRPQVPTPAPLLPDAK---------------------------------TTVAPTGSPKPLQPLPAPILTIAPHPGVQPQLAPQQPPPPTLGTLKLAPAEEAKSSEQKKRPG--------------------------------------------------------------------------------GIGTREVHNKLEKNRRAHLKECFETLKRNIPNVDD--KKTSNLSVLRTALRYIQSLKRKEKEYEHEMERLAREKIATQQRLAELKHELSQWMDVLEIDRVLRQTGQPEDDQASTSTASEGEDNVDEEMEGDRAGLGPPKLNHRPQPELLKSALPTPSTAPAPLPTHPHPHPHPVALSPAHLPVQQQQPPQQKTPLPAPPP--PPATPTQTLVPAPAHLVATAGGGSTVIAHT-ATTHASVIQTVNHVLQGPGGKHIAHIAPSAPSPAVQLAPATPPIGHITVHPATLNHVAHLGSQLPLYPQPVAVSQPVAVSHIAHTLSHQQVNGTAGLGPPATVMAKP-AVGAQVV-HHPQLVGQTVLNPVTMVTMPSFPVSTLKLA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99583-1", "uniprot_id": "MNT_HUMAN", "id": "Q99583-1", "name": "Max-binding protein MNT", "aln": "----MSIETLLEAARFLEWQAQQ--------------------QQRAREEQERLRLEQER--EQEQKKANSLARLAHTLPVE-------------------------------------------------------------------------------------EPRMEAPPLPLSPPAPPPAPPPPLATPAPLTVIPIPVVTNSPQPLP----PPP-------PLPAAAQPLPLAPRQPALVGAPGLSIKEPAPLPSRPQVPTPAPLLPDSK---------------------------------ATIPPNGSPKPLQPLPTPVLTIAPHPGVQPQLAPQQPPPPTLGTLKLAPAEEVKSSEQKKRPG--------------------------------------------------------------------------------GIGTREVHNKLEKNRRAHLKECFETLKRNIPNVDD--KKTSNLSVLRTALRYIQSLKRKEKEYEHEMERLAREKIATQQRLAELKHELSQWMDVLEIDRVLRQTGQPEDDQASTSTASEGEDNIDEDMEEDRAGLGPPKLSHRPQPELLKSTLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQ-QPQQKTPLPAPPP--PPAAPAQTLVPAPAHLVATAGGGSTVIAHT-ATTHASVIQTVNHVLQGPGGKHIAHIAPSAPSPAVQLAPATPPIGHITVHPATLNHVAHLGSQLPLYPQ------PVAVSHIAHTLSHQQVNGTAGLGPPATVMAKP-AVGAQVV-HHPQLVGQTVLNPVTMVTMPSFPVSTLKLA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AIM1-1", "uniprot_id": "A0A8M3AIM1_DANRE", "id": "A0A8M3AIM1-1", "name": "Max-binding protein MNT", "aln": "----MSIETLLEAAKFLELQALQ--------------------QQKAREENE--LQERRRREQEAEKRRAELNSYTQPIRLN-------------------------------------------------------------------------------------PVPYREESGPERQHIPACQPPPPLP-PMPITVIPIPLVPSTPPALP----PPPT-----TSLSPSAAPRLTPPRK----DASPLPNQHPRPLAP-TQVKTEPTSLPQSN---------------------------------GTKP----AQQIQSYPGSIVTSSQH-ALLPQPAPPSLQTSPVG--RGSPPEDHRGFDGKKRPG--------------------------------------------------------------------------------GAGTREVHNKLEKNRRAHLKECFETLKKNIPNVDE--KKTSNLSVLRSALRYIQTLKRKEKDYEHEMERLAREKIALQQRLAELKNELSQRLDVMEIDRLLRQTVQPDDDQASTSTASEGEDNFDEDIDDDSLSSMPTALPKVP--AALQPELKKSHPLSSLLTQHIHIPHKQSKLPMPSAQLSPIAAATPITTLSSTPNGLASAPAPQTLPPAHTHIVTAASLQPSVIAHAGSASHASVIQTVNHVIQ-PASKHMAHIAPSSSSP-VQLAPGPQSISHIT--------VAHLPG---IYPQPVTVTQPAVMSHIAHTLSHAQINGTAAPSAQAAIMAKQTPVGAQVVAHHPQLVGQTVLNPVTMVTMPSFPVSTLKLA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9NGP0-1", "uniprot_id": "M9NGP0_DROME", "id": "M9NGP0-1", "name": "Max-binding protein MNT", "aln": "MSGIGGIGVLLEAAQFLEQHEKLPQAGGGGGSALGVGVALPQQQQQTVHCKSNSIINNNNSSQHNRNSSSSSNGIIATPPFTNGNGNGTVGVGNASAIFNVSVNANGNGLSNGHSSPRSQLAAAATAHDYEYSAAGVANGHSEGRPHVSEDDNSSINNNNNNNNTHPPQQQQHSAAGRTTTTRITTTPAILTKLMGNSVTPASNTTSLPTSTPSVTTSPPASTDFMLLAAAATSATSATPATATSAAATAASNPAKRKLSSIAEIPSKFLVVSDAKGVYSAHTHPNGFAADSLGVDNNETMIKKLMQNLQSQRQQQSLQQLRSLRPAEISLTPPPAATRKVDISNSRTRSYSLSNVSAARDQQDHPQHQQHANHMQIQQHYGYMRSNIGGVIYGLHKDSADSAASSACGAGAGAAAVGMSIASSAPAAGSQLSAHHHTGHGGRRRTTSSNSNGAGTREVHNKLEKERRAQLKECYDLLKKVLPMGDEDRKKTSNLTILDTAHKYVNSLSHEVCEQEAKIEKLAKQKIELQKRLKQLSLRRESPPTDQQIIPQADKVCLATTATTAPPTAASGHNGTTILFDAGNACATGQQL-----TTVINKTNGGATAAASSKHNGNHTGGATTTLTPAMGIMTIKNGNGSNGNMLAISP------TGGHNHQLHQHHNGSPAGSPSGIGAT----------TGATITRGSPTPSTPSPSPSSSSSGVSLS------------------TSFMGGSSSSSSSSSSSSSSSSSSSSSSPTQQQQIITPTATARSVGLKFHG-GAGAAVPAGGGSVNGFHQADKDRNYTFLRLSAGTTAQ-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* .*****:*** : **:: . :. :... :. .: . . . . . .*. *. :* * . ... * . * .** ..:: . .* :. . *.. .:: : :.::: : : ::. . :: : . : . . . . . :...: :. ::: . * ***********:***:****:: **: :* *: ******::* :* :*:::*.:: : * ::*:**::** *:** :*. . .. :* :. . ::..**:.*.:. :: . * :: . . .: * *. . : : : . . * :.. .: *. : * : : . . :**:.*. *.*: .:.: . .. . * : . .: *: .:. . . : : .** * .: * : *: :...* ", "identical_positions": 87, "similar_positions": 183, "identity": "10.47%" }, { "cls_id": "homologset.agr.RGD:1308684", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZSR7-1", "uniprot_id": "D3ZSR7_RAT", "id": "D3ZSR7-1", "name": "Coiled-coil domain-containing protein 102A", "aln": "MSHGPSPRLAESPQLSKSSLLTILGSPSPERMGPADSLPPTPPSGTPSPGPPPTLPLT-APALLADGDWESREELRLRELEEARARALQMEKTMRWWSDCTANWREKWSKVRAERNRAREEVRQLRQRLDTLTKELAGARRERQEAQGECEARGRELARLR-------GARGAADKTQEGPEAER--------------------------------EHEPVRDIGAERSPGSQ-ELDLVESLLKSRPEELEGCWDAC---SVAAGGSRVSSGRQDRNRLPWEDTAGTEED--TSKLTALRLRLDESQKVLLKEREDKLALSKNIEKLEGELSQWKIKYEELSKTKQEMLKQLSILKETHQDELGRMSEDLEDELGARSSMDRKMAELRGEMERLQAENAAEWGRRERLETEKLGLERENKKLRAQVGDLEEALARRRRQNASALDCDLRASQAALFEKNKELADLKHVHSKLKKQFQEKVAELAHANRRVEQHETEVKKLRLRVEELKKELAQAEDELDEAHNQARKLQRSLDEQTEQSENLQVQLEHLQSRLR-----RQQQNAPLFGKIR--------------------------STRFGTEEAGDGASDL---DEDED--LQIQVA------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TMW1-1", "uniprot_id": "C102A_MOUSE", "id": "Q3TMW1-1", "name": "Coiled-coil domain-containing protein 102A", "aln": "MSHGPSPRLAESPQLSKSSLLTILGSPSPERMGPADSLPPTPPSGTPSPGPPPSLPLT-APALLADGDWESREELRLRELEEARARALQMEKTMRWWSDCTANWREKWSKVRAERNRAREEVRQLRQRLDTLTKELAGARRERQEAQGECEARGRELARLR-------GVHSAADKTHDGPEPER--------------------------------EQEPVRDIGAERPPGSQ-ELDLVESLLKSRPEEPEGCWDAC---SVAAGGPRVSSGRQDRNRLPWEDTASTEED--ASKLTALRLRLDESQKVLLKEREDKLALSKNIEKLEGELSQWKIKYEELSKTKQEMLKQLSILKETHQDELGRMSEDLEDELGARSSMDRKMAELRGEMERLQAENAAEWGRRERLETEKLGLERENKKLRAQVGDLEEALARRRRQNASALDCDLRASQAALFEKNKELADLKHVHGKLKKQFQEKVAELAHANRRVEQHETEVKKLRLRVEELKKELAQAEDELDEAHNQARKLQRSLDEQTEQSENLQVQLEHLQSRLR-----RQQQNAPLFGKIR--------------------------STRFGTEEAGDGASDL---DEDED--LQIQVA------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96A19-1", "uniprot_id": "C102A_HUMAN", "id": "Q96A19-1", "name": "Coiled-coil domain-containing protein 102A", "aln": "MSHGPSPRLAESPQLSKGSLLTILGSPSPERMGPADSLPPTPPSGTPSPGPPPALPLPPAPALLADGDWESREELRLRELEEARARAAQMEKTMRRWSDCTANWREKWSKVRAERNRAREEVRQLRQRLDALTKELAGARRERQEAQGECEARGRELARLR-------GARGVADQTRDGPEPEA--------------------------------EREPVRDVGSERPPGSQ-ELELVESLLKSMPEESEDCWEAR---SLGAGGPRGSSGRQERSRLPWEDTAATEEE--ASKLTALRLRLDESQKVLLKEREDKLALSRNIEKLEGELSQWKIKYEELSKTKQEMLKQLSILKEAHQDELGRMSEDLEDELGARSSMDRKMAELRGEMERLQAENAAEWGRRERLETEKLGLERENKKLRAQVGDLEEALARRRRQTASALDCDLRASQAALFEKNKELADLKHVHGKLKKQFQEKVAELAHANRRVEQHEAEVKKLRLRVEELKKELAQAEDELDEAHNQARKLQRSLDEQTEQSENLQVQLEHLQSRLR-----RQQQNAPLFGKIR--------------------------SARFGTEEAEDGTSDL---DEDED--LQIQVA------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NZW0-1", "uniprot_id": "C102A_DANRE", "id": "Q6NZW0-1", "name": "Coiled-coil domain-containing protein 102A", "aln": "MNHTPSPHMTEAAKSGAG-LLCGLG-LGPDRVRSPDSLTHTPSPSGGTPSSSPPLLLSPGLGCDGIGDWESREELRLRELEEARARAAQMEKTMRWWSDCTANWREKWSKVRAERNRARDEVRQLRQRLDALTKELTGARRERQELAAENEQLRLEAQRVR-------AEQSSPENASTAPESISSTASTHSNQPREAEIKQDNQDEEGVRDGPGSPEQEPVRDIGTDKLYKQK-EMELLEALLRAKSEAP-DSWDGR---SASS--LRSALSRQDRNRLLWEDLAALEED--TSKLNALQLRLDESQKVLLKEREDKHALIKNIEKLEAELSQWKLKYEELNKSKQEALKQLNLLKEVHQDELGRMSEDLEDELGARTNMDKKLAELRTEMERLQVENAAEWGRRERLETEKLALERENKKLRTQMEDLEEQLARKRRQAASALDTDLKTIQSELFERNKELADLRHVHSKVKKQYQEKMAELTHANRRVEQHEAEVKKLRLRVEELKKELGQAEDELDEAHNQTRKLQRSLDEQVEQSENLQVQLEHLQSRLR-----RQQ-NPGLFGKMRTSA-----------------------SSRFGPEDADGPPSDP---DEDEEEELQLQIP------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VMC7-1", "uniprot_id": "Q9VMC7_DROME", "id": "Q9VMC7-1", "name": "Coiled-coil domain-containing protein 102A", "aln": "MSQTASTTQSVTAAPAGG--------SRRNEVGGVGVIGTTMS------------------ARYGETEWEARESQRQRELHEARARAAQMEKTMKWWSDCTANWREKWSKVRNERNKAREESKQLSLKLDGVMKEAHSLKREKNDLELQITQLKKEMEKVHTLMMKHAGQFHRADTSEDAEANGR--------------------------------DANCSPDISSDGLKNINSEDGLVTKLPNDVKDLDIEEFAMKGAMPKHLTELDEAAAAEEKRLIQQLSKDDFDEDYLLQKISMLQLRLDEAQKTLQAERDEKLELHKSIEKLTLEIQDVRGRQEEMRSAKQEAVRELLTLQEQHRAEMRIVNNSLQEEIAARENLERRLTELRTELEHLQAENASEWGKRERLESEKLAMERDNKKLRAELRDYQERSDRKCRP-MQANDVELRALQQELSERNKEISEVKMSHAKLKKLLAETNTELGHAVRRAEQYEAEVKRLRQRVEELKRELAGAEDELDSAVNQVRRLQRSNDELVGQTEGLQVQIQHLQNRRAPSPQLRGMGGVQLRNKIAVELPNDCLPNINDLRQIFDDSQAGLRSSHNGSDAAMHHAASVKRSSHTERTLLQQQQSSAAASAAAAAAAAAAFFDAKPTHLEENIFESKSRNLEFERAKQKFDNPHGQHHHHHQRQRSGNGRYGSAGSSASRANLALPLKGTTNGGSSSVSSKDELNRQLYEKEQSAGAGYARNSINLDGLKVSDDETP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.: .*. : :. . . :.: . : * . . . :**:**. * ***.****** ******: **************** ***:**:* :** :** : ** . :**::: : * ::: . .: : . : : *:.:: : * *: * . : : . : . ::: : . :*: .*:. *:*****:**.* **::* * :.**** *:.: : : **: .:*** :::* *:* *: *: :.:.*::*:.** .::::::*** *:*:**.***:***:*****:***.:**:*****::: * :* *: * .* * :*:: * * *:***::::: *.*:** *. :** ** **.**:*:***:** ******:**. ******.* **.*:**** ** . *:*.****::***.* * . * .*: *:: *.: * .:. .. * ** * . ", "identical_positions": 196, "similar_positions": 157, "identity": "25.69%" }, { "cls_id": "homologset.agr.RGD:1308685", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z0M9-1", "uniprot_id": "D3Z0M9_MOUSE", "id": "D3Z0M9-1", "name": "Probable ATP-dependent RNA helicase DDX23", "aln": "MAGELADKKDRDASP-KEERKRSRTPERDRDRDRDRKSSPSKDRKRHRSRDRRRGGSRSRSRSRSKSVERERRHKERERDKERDRSKKERERDKDGHRRDKDRKRSSLSPGRGKDFKSRKDRDSKKGDEDEHGDKRPKIQPLSLEELLAKKKAEEEAEAKPKFLSKAEREAEALKRRQQEVEERQKMLEEERKKR----KQFQDLGRKMLE---------DPQERERRER---RERMERETNGNEDEEGRQKIREEKDKSKELHAIKERYLGGIKKRRRTRHLNDRKFVFEWDASEDTSIDYNPLYKERHQVQLLGRGFIAGIDLKQQKREQSRFYGDLMEKRRTLEEKEQEEARLRKLRKKEAKQRWDDRHWSQKKLDEMTDRDWRIFREDYSITTKGGKIPNPIRSWKDSSLPP--HILEVIDKCGYKEPTPIQRQAIP---IGLQNRDIIGVAETGSGKTAAFLIPLLVWITTLPKIDRIEESDQGPYAIILAPTRELAQQIEEETIKFGKPLG------IRTVAVIGGISREDQGFRLRMGCEIVIATPGRLIDVLENRYLVLSRCTYVVLDEADRMIDMGFEPDVQKILEHMPVSNQKPDTDEAEDPEKMLANFESGKHKYRQTVMFTATMPPAVERLARSYLRRPAVVYIGSAGKPHERVEQKVFLMSESEKRKKLLAILEQGFDPPIIIFVNQKKGCDVLAKSLEKMG-YNACTLHGGKGQEQREFALSNLKAGAKDILVATDVAGRGIDIQDVSMVVNYDMAKNIEDYIHRIGRTGRAGKSGVAITFLTK-EDSAVFYELKQAILESPVSSCPPELANHPDAQHKPGTILTKKRREETIFA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3V9M1-1", "uniprot_id": "G3V9M1_RAT", "id": "G3V9M1-1", "name": "Probable ATP-dependent RNA helicase DDX23", "aln": "MAGELADKKDRDASP-KEERKRSRTPERDRDRDRDRKSSPSKDRKRHRSRDRRRGGSRSRSRSRSKSTERERRHKERERDKERDRSKKERERDKDGHRRDKDRKRSSLSPGRGKDFKSRKDRDSKKGDEDEHGDKRPKIQPLSLEELLAKKKAEEEAEAKPKFLSKAEREAEALKRRQQEVEERQKMLEEERKKR----KQFQDLGRKMLE---------DPQERERRER---RERMERETNGNEDEEGRQKIREEKDKSKELHAIKERYLGGIKKRRRTRHLNDRKFVFEWDASEDTSIDYNPLYKERHQVQLLGRGFIAGIDLKQQKREQSRFYGDLMEKRRTLEEKEQEEARLRKLRKKEAKQRWDDRHWSQKKLDEMTDRDWRIFREDYSITTKGGKIPNPIRSWKDSSLPP--HILEVIDKCGYKEPTPIQRQAIP---IGLQNRDIIGVAETGSGKTAAFLIPLLVWITTLPKIDRIEESDQGPYAIILAPTRELAQQIEEETIKFGKPLG------IRTVAVIGGISREDQGFRLRMGCEIVIATPGRLIDVLENRYLVLSRCTYVVLDEADRMIDMGFEPDVQKILEHMPVSNQKPDTDEAEDPEKMLANFESGKHKYRQTVMFTATMPPAVERLARSYLRRPAVVYIGSAGKPHERVEQKVFLMSESEKRKKLLAILEQGFDPPIIIFVNQKKGCDVLAKSLEKMG-YNACTLHGGKGQEQREFALSNLKAGAKDILVATDVAGRGIDIQDVSMVVNYDMAKNIEDYIHRIGRTGRAGKSGVAITFLTK-EDSAVFYELKQAILESPVSSCPPELANHPDAQHKPGTILTKKRREETIFA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BUQ8-1", "uniprot_id": "DDX23_HUMAN", "id": "Q9BUQ8-1", "name": "Probable ATP-dependent RNA helicase DDX23", "aln": "MAGELADKKDRDASPSKEERKRSRTPDRERDRDRDRKSSPSKDRKRHRSRDRRRGGSRSRSRSRSKSAERERRHKERERDKERDRNKKDRDRDKDGHRRDKDRKRSSLSPGRGKDFKSRKDRDSKKDEEDEHGDKKPKAQPLSLEELLAKKKAEEEAEAKPKFLSKAEREAEALKRRQQEVEERQRMLEEERKKR----KQFQDLGRKMLE---------DPQERERRER---RERMERETNGNEDEEGRQKIREEKDKSKELHAIKERYLGGIKKRRRTRHLNDRKFVFEWDASEDTSIDYNPLYKERHQVQLLGRGFIAGIDLKQQKREQSRFYGDLMEKRRTLEEKEQEEARLRKLRKKEAKQRWDDRHWSQKKLDEMTDRDWRIFREDYSITTKGGKIPNPIRSWKDSSLPP--HILEVIDKCGYKEPTPIQRQAIP---IGLQNRDIIGVAETGSGKTAAFLIPLLVWITTLPKIDRIEESDQGPYAIILAPTRELAQQIEEETIKFGKPLG------IRTVAVIGGISREDQGFRLRMGCEIVIATPGRLIDVLENRYLVLSRCTYVVLDEADRMIDMGFEPDVQKILEHMPVSNQKPDTDEAEDPEKMLANFESGKHKYRQTVMFTATMPPAVERLARSYLRRPAVVYIGSAGKPHERVEQKVFLMSESEKRKKLLAILEQGFDPPIIIFVNQKKGCDVLAKSLEKMG-YNACTLHGGKGQEQREFALSNLKAGAKDILVATDVAGRGIDIQDVSMVVNYDMAKNIEDYIHRIGRTGRAGKSGVAITFLTK-EDSAVFYELKQAILESPVSSCPPELANHPDAQHKPGTILTKKRREETIFA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VJ74-1", "uniprot_id": "Q9VJ74_DROME", "id": "Q9VJ74-1", "name": "Probable ATP-dependent RNA helicase DDX23", "aln": "---MVNDKKRRSRSR---ERHREDRPAVGNPRDRERERDRVRERDRQFDREKER--RQRRSRSREDRNRRRSPERQRPRDNVRERSR-ERGGGAGGGGGGGAEKKAKMDTGDAPPKPLIVDDEEQQDGK----EAKVKKEPLSLEELLDKKKREEEARSKPVFLTKEQRALEAIKRRQEEVERQRAAHDAAREQMAAASKVSISMGTAMASGAPPPAIVAPPPKPDRRERGGGRDRGDRIDRGERGDDKRAEDLTHKDKEKELEAIRERYLGIIKKKRRVRRLNDRKFVFDWDAGEDTSIDYNNLYKERHHVQFFGRGNVAGIDIKEQKRTQSKFYGDLLEKRRTEAEKEQEKVRLKKMKRKEDKQKWDDRHWSEKENDEMTERDWRIFREDYNVTIKGGRIPNPIRSWNESGFPK--EIIDIIDKVGYKEPTPIQRQAIP---IGLQNRDIIGVAETGSGKTLAFLIPLLSWIQSLPKIERLEDVDQGPYAIIMAPTRELAQQIEEETTKFGQPLG------IRTVVVVGGLSREEQGFRLRLGCEIVIATPGRLIDVLENRYLVLNQCTYIVLDEADRMIDMGFEPDVQKILEYMPVTNLKPDTEEAEDETKLMENFYT-KKKYRQTVMFTATMPPAVERLARTYLRRPATVYIGSVGKPTERTEQIVYMMGENDKRKKLMEILSRKIDPPVIIFVNQKKGADVLAKGLEKLG-YNSCTLHGGKGQEQREYALAALKSGAKDILVATDVAGRGIDIKDVSLVINYDMAKTIEDYTHRIGRTGRAGKTGCAISFVTK-DDSALFYDLKQCVSASPVSTCPPELMNHPEAQHKPGTVVTKKRREEKIFA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P23394-1", "uniprot_id": "PRP28_YEAST", "id": "P23394-1", "name": "Pre-mRNA-splicing ATP-dependent RNA helicase PRP28", "aln": "--------------------------------------------------------------------------MARPID------------------------VSQLIAGINKKK--------------------------GLDENTSGKIS------KPRFLNKQERS------KQERLKENEESLTP-----------------------------------------------------TQSDSAKVEIKKVNSRDDSFFNETN------DKKRNPSKQNGSKFHFSWNESEDTLSGYDPIVSTR-AIDLLWKG---------------------------------------KTPKNAAESSYMGKHWTEKSLHEMNERDWRILKEDYAIVTKGGTVENPLRNWEELNIIPRDLLRVIIQELRFPSPTPIQRITIPNVCNMKQYRDFLGVASTGSGKTLAFVIPILIKMSRSPPRPPSLKIIDGPKALILAPTRELVQQIQKETQKVTKIWSKESNYDCKVISIVGGHSLEEISFSLSEGCDILVATPGRLIDSLENHLLVMKQVETLVLDEADKMIDLGFEDQVTNILTKVDIN-----ADSAVN---------------RQTLMFTATMTPVIEKIAAGYMQKPVYATIGVETGSEPLIQQVVEYADNDEDKFKKLKPIVAKYDPPIIIFINYKQTADWLAEKFQKETNMKVTILHGSKSQEQREHSLQLFRTNKVQIMIATNVAARGLDIPNVSLVVNFQISKKMDDYIHRIGRTGRAANEGTAVSFVSAAEDESLIRELYKYVRKH-----DPLNSNIFSEAVKNKYNVGKQLSNEIIY-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * :.: .* .*:* * ** **.* :* :*:.::... ..:. : : :.:...: : .*:*. : *. ** *.*: .*** .*: : . * :::: :* * :: :. : .:**::*. .**.:*****::*** :. *** : **:*.*:: .: : :*:: : .****** :** * **::***.****** **:**:* : * . :** *:*:******.***::** *. : . :.: ::** * *: .* * **:*::******** ***: **:.: :******:***:*** :* :** : :. ::.* : ***:******.*.:*::* *:::*. . ** . :* * .:.:.: * : : ***:***:* *: .* **: ::* : ***.*.*****.:* :::. :*::**:**.**:** :**:*:*::::*.::** *********.: * *::*:: :*.::: :* : : * * . * : *: :* *: ", "identical_positions": 205, "similar_positions": 192, "identity": "24.15%" }, { "cls_id": "homologset.agr.RGD:1308686", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P81183-1", "uniprot_id": "IKZF2_MOUSE", "id": "P81183-1", "name": "Zinc finger protein Helios", "aln": "---------------METDAIDGYITCDNELSPEGEHANMAIDLTSSTPNGQHASPSHMTSTNSVKLEMQSDEECDRQPLSREDEIRGHDEGSSLEEPLIESSEVADNRKVQDLQGEGGIRLPNGKLKCDVCGMVCIGPNVLMVHKRSHTGERPFHCNQCGASFTQKGNLLRHIKLHSGEKPFKCPFCSYACRRRDALTGHLRTHSVGKPHKCNYCGRSYKQRSSLEEHKERCHNYLQNVSMEAAGQVMSHHVPPMEDCKEQEPIMDNNISLVPFERPAVIEKLTANMGKRKSSTPQKFVGEKLMRFSYPDIHFDMNLTYEKEAELMQSHMMDQAINNAITYLGAEALHPLMQHAPSTIAEVAPVISSAYSQVYHPNRIERPISRETSDSHENNMDGPISLIRPKSRPQEREASPSNSCLDSTDSESSHDDRQSYQGNPALNPKRKQSPAYMKEDVKALDATKAPKGSLKDIYKVFNGEGEQIRAFKCEHCRVLFLDHVMYTIHMGCHGYRDPLECNICGYRSQDRYEFSSHIVRGEHTFH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LIN9-1", "uniprot_id": "A0ABK0LIN9_RAT", "id": "A0ABK0LIN9-1", "name": "", "aln": "MFFNQRTISFHCTLTMETDGIDGYITCDNELSPEGEQATMAIDLTSSTPNGQHASPGHMTSTNSVKLEMQSDEECDRQPLSREDEIRGHDEGSSLEDPLIESGEVADNRKVQDLQGEGGIRLPNGKLKCDVCGMVCIGPNVLMVHKRSHTGERPFHCNQCGASFTQKGNLLRHIKLHSGEKPFKCPFCSYACRRRDALTGHLRTHSVGKPHKCNYCGRSYKQRSSLEEHKERCHNYLQNVSMEAAGQVMSHHVPPMEDCKEQEPIMDNNISLVPFERPAVIEKLTANMGKRKSSTPQKFVGEKLMRFSYPDIHFDMNLTYEKEAELMQSHMMDQAINNAITYLGAEALHPLMQHAPSTIAEVAPVISSAYSQVYHPNRIERPISRETADSHENNMDGPISLIRPKSRPQEREASPSNSCLDSTDSESSHDDRQSYQGNPALNPKRKQSPPYMKEDVKALDATKAPKGSLKDIYKVFNGEGEQIRAFKCEHCRVLFLDHVMYTIHMGCHGYRDPLECNICGYRSQDRYEFSSHIVRGEHTFH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UKS7-1", "uniprot_id": "IKZF2_HUMAN", "id": "Q9UKS7-1", "name": "Zinc finger protein Helios", "aln": "---------------METEAIDGYITCDNELSPEREHSNMAIDLTSSTPNGQHASPSHMTSTNSVKLEMQSDEECDRKPLSREDEIRGHDEGSSLEEPLIESSEVADNRKVQELQGEGGIRLPNGKLKCDVCGMVCIGPNVLMVHKRSHTGERPFHCNQCGASFTQKGNLLRHIKLHSGEKPFKCPFCSYACRRRDALTGHLRTHSVGKPHKCNYCGRSYKQRSSLEEHKERCHNYLQNVSMEAAGQVMSHHVPPMEDCKEQEPIMDNNISLVPFERPAVIEKLTGNMGKRKSSTPQKFVGEKLMRFSYPDIHFDMNLTYEKEAELMQSHMMDQAINNAITYLGAEALHPLMQHPPSTIAEVAPVISSAYSQVYHPNRIERPISRETADSHENNMDGPISLIRPKSRPQEREASPSNSCLDSTDSESSHDDHQSYQGHPALNPKRKQSPAYMKEDVKALDTTKAPKGSLKDIYKVFNGEGEQIRAFKCEHCRVLFLDHVMYTIHMGCHGYRDPLECNICGYRSQDRYEFSSHIVRGEHTFH", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***:.************** *::.*****************.********************:******************:*****.*********:****************************************************************************************************************************************************************************.********************************************************************.********************************:*******************************************:*****:***********.**********:********************************************************************************", "identical_positions": 508, "similar_positions": 17, "identity": "93.9%" }, { "cls_id": "homologset.agr.RGD:1308687", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "B0K032-1", "uniprot_id": "B0K032_RAT", "id": "B0K032-1", "name": "Protein tyrosine phosphatase type IVA 3", "aln": "---MARMN--RPAPVEVSYRHMRFLITHNPSNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLLKAKFYNDPGSCVAVHCVAGLGRAPVLVALALIESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D658-1", "uniprot_id": "TP4A3_MOUSE", "id": "Q9D658-1", "name": "Protein tyrosine phosphatase type IVA 3", "aln": "---MARMN--RPAPVEVSYRHMRFLITHNPSNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLLKAKFYNDPGSCVAVHCVAGLGRAPVLVALALIESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75365-1", "uniprot_id": "TP4A3_HUMAN", "id": "O75365-1", "name": "Protein tyrosine phosphatase type IVA 3", "aln": "---MARMN--RPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O61722-1", "uniprot_id": "PRL1_DROME", "id": "O61722-1", "name": "PRL-1 phosphatase", "aln": "MSITMRQKDLRPAPALIEYKGMKFLITDRPSDITINHYIMELKKNNVNTVVRVCEPSYNTDELETQGITVKDLAFEDGTFPPQQVVDEWFEVLKDKYQQNPEACVAVHCVAGLGRAPVLVALALIELGLKYEAAVEMIRDKRRGAINAKQLSFLEKYKPKARLKHKN--GHKNSCSVQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : ****. :.*: *:****..*:: *:. :* :*** ...******* :*:. **.:**** * .*:**: ** :**::*:.::* *: : * :*********************** *:*** *:::**:*******:***::****:** **:.*: **. *.* ", "identical_positions": 96, "similar_positions": 49, "identity": "53.93%" }, { "cls_id": "homologset.agr.RGD:1308688", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P98197-1", "uniprot_id": "AT11A_MOUSE", "id": "P98197-1", "name": "Phospholipid-transporting ATPase IH", "aln": "-------------------------------------------------------------------------------MDCSLLRTLVRRYCAGEENWVDSR------------------TIYVGHKEPPPGAEAYIPQRYPD--NRIVSSKYTFWNFIPKNLFEQFRRIANFYFLIIFLVQLIIDTPTS-PVTSGLPLFFVITVTAIKQGYEDWLRHKADNAMNQCPVHFIQHG--------------------------------------------------------------KLVRKQSRKLRVGDIVMVKEDETFPCDLIFLSSNRADGTCHVTTASLDGESSHKTHYAVQDT-KGFHTEADVDSLHATIECEQPQPDLYKFVGRINVYNDLN-----DPVVRPLGSENLLLRGATLKNTEKIFGVAIYTGMETKMALNYQSKSQKRSAVEKSMNTFLIVYLCILVSKALINTVLKYVWQSEPFRDEPWYNEKTESERQRNLFLRAFTDFLAFMVLFNYIIPVSMYVTVEMQKFLGSYFITWDEDMFDEEMGEGPLVNTSDLNEELGQVEYIFTDKTGTLTENNMAFKECCIEGHVYVP---------------HVICNGQVLPDSSGIDMIDSSPGVCGREREELFFRAICLCHTVQVKDDH----------------------CGDDVDGPQKSPD--AKSCV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YISSSPDEVALVEGVQRLGFTYLRLKDNYMEILNRE-----------NDIERFELLEVLTFDSVRRRMSVIVKS--TTGEIYLFCKGADSSIFPRVIEG---------------------------------------------------------------------------------------------------------------------------------------------------------------------KVDQVRSRVERNAVEGLRTLCVAYKRLEPEQYEDACRLLQSAKVALQDREKKLAEAYEQIEKDLVLLGATAVEDRLQEKAADTIEALQKAGIKVWVLTGDKMETASATCYACKLFRRSTQLLELTTKKLEEQSLHDVLFDLSKTVLRCSGSMTRDSFSGLSTDMHDYGLIIDGAALSLIMKPREDGSSS-GNYRELFLEICRNCSAVLCCRMAPLQKAQIVKLIKFSKEHPITLAIGDGANDVSMILEAHVGIGVIGKEGRQAARNSDYAIPKFKHLKKMLLVHGHFYYIRISELVQYFFYKNVCFIFPQFLYQFFCGFSQQTLYDTAYLTLYNISFTSLPILLYSLMEQHVGIDVLKRDPTLYRDIAKNALLRWRVFIYWTFLGVFDALVFFFGAYFIFENTTVTINGQ--------MFGNWTFGTLVFTVMVLTVTLK-LALDTHYWTWINHFVIWGSLLFYIAFSLLWGGVIWPFLSYQRMYYVFISMLSSGPAWLGIILLVTVGLLPDVLKKVLCRQLWPTATERTQNIQ---------------HQDSISEFTPLASLPSWGAQGSR---------LLAAQCSSPSGRVVCSRWESE-ECPVLPLHPGLPHKARYGCCRSSLEMPT----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A7K5-1", "uniprot_id": "D4A7K5_RAT", "id": "D4A7K5-1", "name": "Phospholipid-transporting ATPase", "aln": "-------------------------------------------------------------------------------MDCSLLRTLVRRYCAGEENWVDSR------------------TIYVGHKEPPPGAEAYIPQRYPD--NRIVSSKYTFWNFIPKNLFEQFRRIANFYFLIIFLVQLIIDTPTS-PVTSGLPLFFVITVTAIKQGYEDWLRHKADSAMNQCPVHFIQHG--------------------------------------------------------------KLVRKQSRKLRVGDIVMVKEDETFPCDLIFLSSNRADGTCHVTTASLDGESSHKTHYAVQDT-KGFHTEADVDSLHATIECEQPQPDLYKFVGRINVYNDLN-----DPVVRPLGSENLLLRGATLKNTEKIFGVAIYTGMETKMALNYQSKSQKRSAVEKSMNTFLIVYLCILVSKALINTVLKYVWQSEPFRDEPWYNQKTESERQRNLFLRAFTDFLAFMVLFNYIIPVSMYVTVEMQKFLGSYFITWDEDMFDEEMGEGPLVNTSDLNEELGQVEYIFTDKTGTLTENNMAFKECCIEGHVYVP---------------HVICNGQVLPDSSGIDMIDSSPGVSGREREELFFRAICLCHTVQVKDDH----------------------CGDDVDGPQKSPD--AKSCV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YISSSPDEVALVEGMQRLGFTYLRLKDNYMEILNRE-----------NDIERFELLEVLTFDSVRRRMSVIVKS--TTGEIYLFCKGADSSIFPRVIEG---------------------------------------------------------------------------------------------------------------------------------------------------------------------KVDQVRSRVERNAVEGLRTLCVAYKRLEPEQYEDACRLLQDAKVALQDREKKLAEAYEQIEKDLILLGATAVEDRLQEKAADTIEALQKAGIKVWVLTGDKMETASATCYACKLFRRSTQLLELTTKKLEEQSLHDVLFELSKTVLRCSGSLTRDSFSGLSTDMHDYGLIIDGAALSLIMKPREDGSSS-GNYRELFLEICRNCSAVLCCRMAPLQKAQIVKLIKFSKEHPITLAIGDGANDVSMILEAHVGIGVIGKEGRQAARNSDYAIPKFKHLKKMLLVHGHFYYIRISELVQYFFYKNVCFIFPQFLYQFFCGFSQQTLYDTAYLTLYNISFTSLPILLYSLMEQHVGIDVLKRDPSLYRDIAKNALLRWRLFIYWTFLGVFDALVFFFGAYFMFENTTVTINGQ--------MFGNWTFGTLVFTVMVFTVTLK-LALDTHYWTWINHFVIWGSLLFYIVFSLLWGGIIWPFLSYQRMYYVFIYMLSSGPAWLGIILLVTVGLLPDVLKKVLCRQLWPTATERTQTVQ---------------LRDSISEFTPLASLQSRGAQGTR---------LLAAQCSSPSGRVVCSRWESE-EYPVLPTHPGLLHKARYGCCRSSLETPT----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P98196-1", "uniprot_id": "AT11A_HUMAN", "id": "P98196-1", "name": "Phospholipid-transporting ATPase IH", "aln": "-------------------------------------------------------------------------------MDCSLVRTLVHRYCAGEENWVDSR------------------TIYVGHREPPPGAEAYIPQRYPD--NRIVSSKYTFWNFIPKNLFEQFRRVANFYFLIIFLVQLIIDTPTS-PVTSGLPLFFVITVTAIKQGYEDWLRHKADNAMNQCPVHFIQHG--------------------------------------------------------------KLVRKQSRKLRVGDIVMVKEDETFPCDLIFLSSNRGDGTCHVTTASLDGESSHKTHYAVQDT-KGFHTEEDIGGLHATIECEQPQPDLYKFVGRINVYSDLN-----DPVVRPLGSENLLLRGATLKNTEKIFGVAIYTGMETKMALNYQSKSQKRSAVEKSMNAFLIVYLCILISKALINTVLKYMWQSEPFRDEPWYNQKTESERQRNLFLKAFTDFLAFMVLFNYIIPVSMYVTVEMQKFLGSYFITWDEDMFDEETGEGPLVNTSDLNEELGQVEYIFTDKTGTLTENNMEFKECCIEGHVYVP---------------HVICNGQVLPESSGIDMIDSSPSVNGREREELFFRALCLCHTVQVKDD-------------------------DSVDGPRKSPDG-GKSCV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YISSSPDEVALVEGVQRLGFTYLRLKDNYMEILNRE-----------NHIERFELLEILSFDSVRRRMSVIVKS--ATGEIYLFCKGADSSIFPRVIEG---------------------------------------------------------------------------------------------------------------------------------------------------------------------KVDQIRARVERNAVEGLRTLCVAYKRLIQEEYEGICKLLQAAKVALQDREKKLAEAYEQIEKDLTLLGATAVEDRLQEKAADTIEALQKAGIKVWVLTGDKMETAAATCYACKLFRRNTQLLELTTKRIEEQSLHDVLFELSKTVLRHSGSLTRDNLSGLSADMQDYGLIIDGAALSLIMKPREDGSS--GNYRELFLEICRSCSAVLCCRMAPLQKAQIVKLIKFSKEHPITLAIGDGANDVSMILEAHVGIGVIGKEGRQAARNSDYAIPKFKHLKKMLLVHGHFYYIRISELVQYFFYKNVCFIFPQFLYQFFCGFSQQTLYDTAYLTLYNISFTSLPILLYSLMEQHVGIDVLKRDPTLYRDVAKNALLRWRVFIYWTLLGLFDALVFFFGAYFVFENTTVTSNGQ--------IFGNWTFGTLVFTVMVFTVTLK-LALDTHYWTWINHFVIWGSLLFYVVFSLLWGGVIWPFLNYQRMYYVFIQMLSSGPAWLAIVLLVTISLLPDVLKKVLCRQLWPTATERVQTKS---------------QCLSV-------------EQSTI---------FMLSQTSS------------------------------------SLSF------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q0D3-1", "uniprot_id": "A0A8M9Q0D3_DANRE", "id": "A0A8M9Q0D3-1", "name": "Phospholipid-transporting ATPase", "aln": "-------------------------------------------------------------------------------MDFSTIRNLITRYCTGEENWVDSR------------------TVYIGHKEPPPGTEAYIPQRFPD--NRIVSSKYTFWNFIPKNLFEQFRRIANFYFLIIFLVQLIIDTPTS-PMTSGLPLFFVITVTAIKQGYEDWIRHKADNSVNQCPVHIVQHG--------------------------------------------------------------KVVRKQSQKLRVGDIVQVKENETFPCDLILLSTSREDGTCFVTTASLDGESSHKTYYAVQDT-KAFSTAEEVDTLHATIECEQPQPDLYKFVGRINIYLDRD-----EPIARPLGSENLLLRGATLKNTEYIHAVAIYTGMETKMALNYQSKSQKRSAVEKSMNAYLIVYLCILISKALINTVLKYVWQADPNRDEPWYNQRTESERQRHVLIRAFTDFLAFMVLFNYIIPVSMYVTVEMQKFLGSYFILWDDDMFDEEVGERPLVNTSDLNEELGQVEYVFTDKTGTLTENNMELRECCVDGHVYVP---------------HAICNGQILPGAAGMDMIDSSPGVEGKEREELFFRALCLCHTVQVKEE-------------------------ETVDGIKRGIHQGKATSF---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YISSSPDEVALVEGMKRLGFTYLRLKDSHMEILNRE-----------DEMERFELLDVLNFDSVRRRMSVIVRS--NSGEYYLFCKGADSSVFPRVVSG---------------------------------------------------------------------------------------------------------------------------------------------------------------------KVEQVRARVEHNAVEGLRTLCVAYKRLSQEEYEETCRLLTSAKLALQERDKKLAEAYDVIEKDFILLGATAVEDRLQDKAADTIESLHKAGIKVWVLTGDKMETAAATCYASKLFHRNTQILELTTKRTEEQSLHDVLFDLSRTVLRQHGSMTRDTFSGLSGDYQDYGLIIDGATLSAVLKPTQDATSNSGNYKEIFLEICRNCSAVLCCRMAPLQKAQIVKLIKASKEHPITLAIGDGANDVSMILEAHVGIGIMGKEGRQAARNSDYAITKFKHLKKMLLVHGHYYYIRIAELVQYFFYKNVCFIFPQFLYQFFCGFSQQPLYDTAYLTLYNISFTSLPILLYSLMEQHINMDILKRDPSLYRDIAKNSLLTWPTFIYWTFLGVFDAVVFFFGAFFLFDNTTFTSNGQLMATNTQMMFGNWTFGTLVFTVLVFTVTLK-LALDTHYWTWINHFVIWGSLLFYVIFSLLWGGIIWPFLNYQRMYYVFMQMLSSGPAWLSIILLIIVSLLPDVLKKVLCRALWPTTTERIQNADKL-------------YKGHLSEFSPLTSLHAPPARKHERRGNERQNHAHRRSDSSPTKKLMCTYWGGKPDYCTFSSFLRIGENPRFSGAAYAYSAPGPETSV-----------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VXG7-1", "uniprot_id": "Q9VXG7_DROME", "id": "Q9VXG7-1", "name": "Phospholipid-transporting ATPase", "aln": "------------------------------------------------------------------------------------------MGADKKK--------------------------SADPLRIQIGG---IESRQQKPLNRVTTTKYTWFTFLPLNFYEQFRRAVYFYFLIITIVSFFVNETIS-PLVSLLPLLFVMIITALKEGLEDYSRSKSDKLVNTARVTVIRNG--------------------------------------------------------------KEEIINSQFIVPGDLVVVRNDGDVPCDLVLLQSSSADRKCFVNTANLDGETNLKTICVPTNY-LLAGDHELQG--KDCIVCEPSSADLYTFNGRLELRSGNDGAGSSAGDALPLTIDNLLLRGVRVKSTERVVGCAIYTGMHTKLQLNSRYTGNKSASSEKYINRFMVALIVGMIVVVVVLYLIERHKEAKIVPTMPYQGPPTNFNS----AWQIFEDFLSFLLLFNYMVPISAYMNIEVYRIFGMHFMHNDLHLYDEETDQPCRVNASNLNEELGQVNILFSDKTGTLTKNLMKFVNCYVPGTNYQL---------------QNTH----LVSEGTDEKFELEKLDAD---AAVLFEALAVCHTVEVLQ-------------------EVGDKTLESSESVSEQSHLMSRN------------------------------------------------IVDR-------------------------------------------------------------------------------------------------------------------------------------------YQASSPDEKALLEGCASLGLVYEGQENDVLSICRYP----------SAEKVQFKRLHVLEFSSERQRMSVIVRD--QSDTIWLYSKGAESAIFPRCKAS--------------------------------------------------------------------------------------------------------------------------------------------------------------------PLVEQTDAQITKYAQNGLRTMAVGRRMLTDDELFHFEELYRKANTQLSNRNELIASCYETVENELDLLGATALEDALQEHVGETLEALQAAGLKIWVLTGDKVETAYNIGLACRHIPRGSKQHFIINTTEPAE------------LLARLD------MIGDD---EPEVLIVDGTTITALLEHTP----------RQFADLALRCRAVLCCRLSPLQKSEIVTLIKR-RKKYITAAIGDGANDVSMIQEAHIGIGITGREGKQAARCADFSIARFEMLRRLFLVHGHYNSQRLAFLVLFYCYKNIIITGCMALYQVYDLYSATNVYNSIYLWLFDIVYISFSFTVLAICDKDYSEETLLSHPELYKPLAHNRQASMGVFSLWILNGFVQCFIIFFFTYAMLNDANVLFNGG-------QTASFQTFGTMLITIIVIVGNLK-LLLVAHYMTYRNFAMILASIAAFMLTTYLY-----NLYTSGELYDVYNQFLSSLPIWLFTIICSVACLLPDFVIKVVN------------DMY----------------------------------RKVP----------LKSKPVV----------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VXG6-1", "uniprot_id": "Q9VXG6_DROME", "id": "Q9VXG6-1", "name": "Phospholipid-transporting ATPase", "aln": "-------------------------------------------------------------------------MNFFGHDHLSGFRRIDRLGAHRQTPWADQESFHLKDAFLWNWHKGSRVSTINDWLQIQIGGPQDIKKKRPKGQNRIKSTKYTLITFLPQNLLEQFRRIANFYFLVMTIISLLIDSPVS-PMTSLLPLVFVIAVTAAKQGYEDILRYRTDNVVNSSPVTVIRDG--------------------------------------------------------------KEAIIKSQDVIPGELIVVERDCDVPCDLVLLRSTDPHGKCFITTANLDGESNLKTLMVPRDL-PTVDLPEMHK--LGIIECESPTTDLYSFNGKIELKGGE-------GRVLPLSTENVLLRGSRVKNTECVIGCAVYTGMISKLQLNSRLTRNKNASSETYINRFLIVILVALIAIVTLLYFLKRYNELFVIPKLTYLGDATDSYS----VKQFLQDYLSFLILFNYLIPISLYVTIELQRVIGSWFMEWDLELYENETDQPCVVNTSNLNEELGQINILFSDKTGTLTKNEMNFQQCSINGNKFLF---------------KKTR----LEDEETKALLDINKFSAN---QRVFFQALSICHTVQVASGSLEQADAGTAKREPVTAIKSGPPEMYSISDITEESHNASQQSELNVGHTIDNSVSAHPNGVNSTIISSDVNPLLVSDDGYGVERRKRPVVIKRSPNFARSNRMNNGAASDLNINQTDPNTVTNGVEPTTNFRPISLQFRRSTSEKDLQQSWEAPSGQAPGHRRAHSYGAPNAYLTNPVTASTPPAGVLFRSPSTTSRESYAAPTFTRQPTILVRAESQRRKNEIRDFIFTLDYQASSPDEKALVEACANLGMVYTGDDDETLRVRIVPPHMDYKRPFAKPREETFQRLHVLEFTSDRKRMSVIVRD--TDGKKWIYTKGAESYVFPLCANSSA------------------------------------------------------------------------------------------------------------------------------------------------------------------ELVTKTDAHISDFARLGLRTLAIARRLISEEEYQDFLVELAQANSSLENRKQLSEECYAKIESNLDLLGATAVEDALQDDVADTLVSLQAAGIKIWVLTGDKVETALNIALSCGHIPPDAKKYFIMECKNREE------------MLLHLNALDREIIFGIG---QECALLIDGKSLGVALAEAS----------SEFRDVAVKCTAVLCCRLSPLQKSEVVSLIKSSNENYNTASIGDGANDVSMIQEAHVGIGIMGREGRQAARCADFAFAKFCMLKRLLLVHGHYHSVRLSLLVLYFFYKNIVFMGIMFLFQFHTLFSSSSVYDSLFLTLYNVIYTSLPILFIAISEKPYTEEKLMRTPQLYKKNTDNKQLHWPYFLMWVLFAIYHSVIIFYFAFCFFYYNNVLLNYG-------QTVAFSCFGTLLMWTVVVVVNLK-LWLESMYLSFWYIFTIIISILGFVVTTVIYN--VINLDYDTDIYWAYNNLLASLPVWLWIIVTCVACLVPDYTIRMLQRALNIKSFSIFPGKQ----------------------------------RKLK----------MREKFESTYL-------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12674-1", "uniprot_id": "ATC8_YEAST", "id": "Q12674-1", "name": "Probable phospholipid-transporting ATPase DNF3", "aln": "MGIADGQRRRSSSLRTQMFNKHLYDKYRGRTDDEIELEDINESKTFSGSDNNDKDDRDETSGNYAAEEDYEMEEYGSPDVSYSIITKILDTILDRRRTFHSKDGRHIPIILDHN------AIEYKQAATKRDGHLIDERFNKPYCDNRITSSRYTFYSFLPRQLYAQFSKLANTYFFIVAVLQMIPGWSTTGTYTTIIPLCVFMGISMTREAWDDFRRHRLDKEENNKPVGVLVKDGNNDAQEVYTLPSSVVSSTAYLTKSAAAENNPPLNDDRNSSQGHFLDTHFNNFELLKNKYNVHIHQKKWEKLRVGDFVLLTQDDWVPADLLLLTCDGENSECFVETMALDGETNLKSKQPHPELNKLTKAASGLANINAQVTVEDPNIDLYNFEGNLELKNHRN----DTIMKYPLGPDNVIYRGSILRNTQNVVGMVIFSGEETKIRMNALKNPRTKAPKLQRKINMIIVFMVFVVATISLFSYLGHVLHKKKYIDQNKAWYLFQADAG------VAPTIMSFIIMYNTVIPLSLYVTMEIIKVVQSKMMEWDIDMYHAETNTPCESRTATILEELGQVSYIFSDKTGTLTDNKMIFRKFSLCGSSWLHNVDLGNSEDNFEDNRDNTNSLRLPPKAHNGSSIDVVSIGDQNVLDRLGFSDAPIEKGHRPSLDNFPKSRNSIEYKGNSSAIYTGRPSMRSLFGKDNSHLSKQASVISPSETFSENIKSSFDLIQFIQRYPTALFSQKAKFFFLSLALCHSCLPKKTHN--------------------------------------------------------------------------------------------------------------------------------ESIGEDSIEYQSSSPDELALVTAARDLGYIVLNRNAQILTIKTFPDGFDG-----EAKLENYEILNYIDFNSQRKRMSVLVRMPNQPNQVLLICKGADNVIMERLHDRELAAKKMADICTSTKERKDAEAELVLQQRKSLERMVDEEAMARTSLRNSLSSVPRASLSLQAVRKSLSMKNSRTRDPEKQIDSIDQFLETVKKSDQEIGSVVNKSRKSLHKQQIEKYGPRISIDGTHFPNNNVPIDTRKEGLQHDYDTEILEHIGSDELILNEEYVIERTLQAIDEFSTEGLRTLVYAYKWIDIGQYENWNKRYHQAKTSLTDRKIKVDEAGAEIEDGLNLLGVTAIEDKLQDGVSEAIEKIRRAGIKMWMLTGDKRETAINIGYSCMLIKDYSTVVILTTTD-----------------ENIISKMNAVSQEVDSGNIAHCVVVIDGATMAMFEGNPT--------YMSVFVELCTKTDSVICCRASPSQKALMVSNIRNTDPNLVTLAIGDGANDIAMIQSADIGVGIAGKEGLQASRVSDYSIGQFRFLLKLLFVHGRYNYIRTSKFMLCTFYKEITFYFTQLIYQRYTMFSGSSLYEPWSLSMFNTLFTSLPVLCIGMFEKDLKPMTLLTVPELYSYGRLSQGFNWLIFMEWVILATTNSLIITFLNVVMWGMSSLS------------DNTMYPLGLINFTAIVALINVKSQFVEMHNRNWLAFTSVVLSCGGWLVWCCALPILNNTDQIYDVAYGFYNHFGKDITFWCTSLVLALLPITLDIVYKTFKVMIWPSDSDIFAELEQKSDIRKKLELGAYSEMRQGWTWDKDPSTFTRYTDKVLSRPRTNSRASAKTHNSSIYSMSNGNVDHSSKKNFFGNSSKKSSERYEVLPSGKLIKRPSLKTQSSKDSIGGNITTKLTKKLKLPSRNVEDEDVNQIIQARLKDLE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * . **: :::** .*:* :: ** : . **::: ::.:: . . : . .: :** ..: :: ::. :* * : *. * * .: .. : : . : *::: : .: .*.**::* . *.: * ****:. *: : : * . ***.* *.::: ** :*:: ** ::.*: : . .:::* :*: :* . .. :. ::. : :: : : . : ::*::::* ::*:* *:.:*: :.. :: * .::. * . .:: : *****:. :*:*******.* * : : : * : . :: : * : : . . . * :***** **: . ** . . : : :: *. : * * *:****:*: . : ***:. :: : : : : ****: . : : : *: * :*. .. :*. : ***.**:** **: ..::: :: **:*:*:***** *** :. : : : . . :::** :: * ::. :*:*** :* **: :*. *: : * :*******::** .*.:*:*: *:** **:* :*::: :* * ::::***:: * : :: **:: : ::* . :* :*:. * ::: : *:.. .: :: * * ** . * * : . ...:: : . .. :* : : :* .:* : .: : * :: * : : . . * :: : * : . ", "identical_positions": 179, "similar_positions": 297, "identity": "9.72%" }, { "cls_id": "homologset.agr.RGD:1308689", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BTJ4-1", "uniprot_id": "ENPP4_MOUSE", "id": "Q8BTJ4-1", "name": "Bis(5'-adenosyl)-triphosphatase enpp4", "aln": "---------------------------------------------------------------------------------------------------------------------------MFNMKILVIPLFWG--------------LVTGYK--GNSSDSSAPRLLLVSFDGFRADYLKSYDLPHLQNFIKEG-------VLVEHVKNVFITKTFPNHYSIVTGLYEESHGIVANSMYDSVTKKHFSESNDKDPFWWN-GAEPIWVTNQLQENR----SSAAAMWPGTDVP-----------------IHNITASYFMNYSSSVSFKERLGNVTTWLSS--SNPPVTFAALYWEEPDVSGHKYGPEDKE-----NMRRVLKEVDDLIGDIVLKLKVLGLWDSLNVIITSDHGMAQCSKNR---------LIDLDSCIDRSNYSVIDLTPVAAILP-KINVTEVYDKLKR---------CNPHMNVYLKEAIPNRFYYQHSSR--------IQPIILVAEEGWTITLNKSSFK----------------LGDHGYD-NSLPSMHPFLAAHGPAFRKGYRQSTINTVDIYPMMCHILGLKPHPNNGTLSHTKCLLVDQWCINLPEAIGIVVSALLVLTMLTGLMIFMRSR-ASTSRPFSRLQLQEDDDD-PLID------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A2W1-1", "uniprot_id": "D4A2W1_RAT", "id": "D4A2W1-1", "name": "Bis(5'-adenosyl)-triphosphatase ENPP4", "aln": "---------------------------------------------------------------------------------------------------------------------------VFNMKLLVILSFWG--------------LVAGYR--GNSSYSSAPQLLLVSFDGFRADYLNNYDLPHLQNFIKEG-------VLVEHVKNVFITKTFPNHYSIVTGLYEESHGIVANSMYDDVTKKHFSESNDKDPFWWN-GAVPIWVTNQLQENR----SSAAAMWPGTDVS-----------------IHNVTPSYFMNYSSSVPFEERLNNVATWLSS--SNPPVTFATLYWEEPDVSGHKYGPEDKF-----NMRRVLKEVDGLIGDLVQKLKALGLWESLNVIITSDHGMAQCSENR---------RIYLDTCINHSDYSVIDLTPVAAILP-KINVTEVYNKLKH---------CNPHMTVYLKEAIPNRFYYQHSDR--------IQPILLVADEGWTIALNTSSSK----------------LGDHGYD-NSLPSMHPFLAAHGPAFRKGYRQSTINTVDIYPMMCYILGLKPHPNNGTFSHSKCLLVDQWCINLPEAIGIVVSALLALTVLTGLIIFMQNR-ASASRPFSRLQLHEDDDDDPLIE------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y6X5-1", "uniprot_id": "ENPP4_HUMAN", "id": "Q9Y6X5-1", "name": "Bis(5'-adenosyl)-triphosphatase ENPP4", "aln": "------------------------------------------------------------------------------------------------------------------------------MKLLVILLFSG--------------LITGFR--SDSSSSLPPKLLLVSFDGFRADYLKNYEFPHLQNFIKEG-------VLVEHVKNVFITKTFPNHYSIVTGLYEESHGIVANSMYDAVTKKHFSDSNDKDPFWWN-EAVPIWVTNQLQENR----SSAAAMWPGTDVP-----------------IHDTISSYFMNYNSSVSFEERLNNITMWLNN--SNPPVTFATLYWEEPDASGHKYGPEDKE-----NMSRVLKKIDDLIGDLVQRLKMLGLWENLNVIITSDHGMTQCSQDR---------LINLDSCIDHSYYTLIDLSPVAAILP-KINRTEVYNKLKN---------CSPHMNVYLKEDIPNRFYYQHNDR--------IQPIILVADEGWTIVLNESSQK----------------LGDHGYD-NSLPSMHPFLAAHGPAFHKGYKHSTINIVDIYPMMCHILGLKPHPNNGTFGHTKCLLVDQWCINLPEAIAIVIGSLLVLTMLTCLIIIMQNR-LSVPRPFSRLQLQEDDDD-PLIG------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q566N0-1", "uniprot_id": "ENPP4_DANRE", "id": "Q566N0-1", "name": "Bis(5'-adenosyl)-triphosphatase enpp4", "aln": "--------------------------------------------------------------------------------------------------------------------------MQISAYLCALIACCG--------------LTLSAPTANNKSSSEAPPLLLVSFDGFRADYLNKYSFPNLEKFFSDG-------VLVHELTNVFTTKTFPNHYSLVTGLYAESHGMLASIMYDPVAKKHFSIKNDSDPFWWD-EATPIWVS-VEESGY----HAASAMWPGSDVN-----------------IQNHTLKYTFKYDSRVSFKERLGNITQWMTT--DKS-LKFASLYWEEPDFSGHTYGPDNTT-----EMARVLKEVDGHVGYLMEELDRMELWGKINVIITSDHGMAQCSEER---------IIRLDDCVSPSSYTLVDLTPVAAIIP-LEDKTTVYNNLSS---------CHVHLKAYMKNDVPDRLHYKNNER--------IQPIILVADEGWTIVKNGRLPR----------------LGDHGYD-NTLPSMHPFLAAHGPAFRKGYKMSSFNSVDLYPLMCHLIGIPPKANNGSFAHVRCTLVNEQCGELALAVGLVMGVLIILTTFTCLFKLMKNRNVSSPRPFARLELDDDGDDEPLLE------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P25353-1", "uniprot_id": "NPP1_YEAST", "id": "P25353-1", "name": "Ectonucleotide pyrophosphatase/phosphodiesterase 1", "aln": "MELQNDLESLDNELNDFSEDPFRDDFITDEDAVRSGWRSAWTRMKYWFYKNRLKWTNNPIVIGDAKDSRDGSNFRRGIPLYELDANGQPIDTELVDENELSFGTGFHSKVPFKIIFRTLFGSLVFAIFLILMINIAKPHHSTRVLSHFGSPEFDPYVKYFNGTHEFFPLTIVISLDGFHPSLISKRNTPFLHDLYELKYDGGMNITSTPFMVPSFPTETFPNHWTLVTGQYPIHHGIVSNVFWDPDLNEEFHPGVLDPRIWNNNDTEPIWQTVQSAFDGDIPFKAATHMWPGSDVNYTKYNEEKLQPEHKNPIARERTPFYFDEFNAKEPLSQKLSKIIEYVDMSTLNERPQLILGYVPNVDAFGHKHGYPSESEYYYEDFTETLGEVDTFLKQLVESLQERNLTSFTNLVIVSDHGMSDIVVPS--NVIIWEDLLDEKLRKDYVSHAYLEGPMMAISLKDSGNINEVYHNLKTSIDED-------KYTVYVNGNFPKEWNFNDGKN------HHMASIWIVPEPGYAVMKKEQLKKVAKGDHKDKNEDNVFTIGSHGYD-NNAIDMRSVFIGMGPYFPQGYIEP-FQNTEIYNLLCDICGVAEKDRNS--NDGTGMLMNQLREPQSSEEVEIEDDFDYLVSKFGEFSTYNIIWGGYPEETEQDNVDNDNDDNDDGNTDEIAAMPSSSLTIKLEMTTSIPSATETLLGETSPSSRSSSSSSIQASATASTVGDWLQDIINDAKDLIDDIIDSIDDLVDSDT", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P39997-1", "uniprot_id": "NPP2_YEAST", "id": "P39997-1", "name": "Ectonucleotide pyrophosphatase/phosphodiesterase 2", "aln": "-----------------------------------------------------------------------------MLLFE-----QPVDLEKNNEDDTNIK-------PFAISRHFLLKLLLCGIILIELLLYSK---CPKPIDNGPRTIANRSNTYFNGTHDFKTLTILISIDGFHPRLIDAKYTPFLYNLHNLRSPYDMNITTAPYMIPSFPTQTFPNHWSMVTGKYPIEHGIVSNIFWDNFTSSEFRPNNLDARIWSN-TADPIWQLLQTESQG--EYKVATHMWPGSEVVYEDHGD----------VPRERMPFYFGKFNQWEKLQDKLAQIFRYIDMPQLKDRPELVISYIPNVDSYGHSFGYDLRD----KRLQKLIGEVDGFFLDLIEGLQKRNLLKISNVMIVSDHGMSNVNANDGEHVVVWERVFPADAMSAFISHLYNEGPMMMVCLKNPRDKQWICDLIEAQLEKAYGDEISRKFHVILKEDFDPSWKYFQYDNRKHRYDDRVGDIWILADEYYAIVK--EMGDVPIG-----------IMGTHGYNFNNCSDMASIFIGMGPMFNNEVVPP-FENIEVYNMLIKASALLGEEKTK--KEKS--LLQ---------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : : . . :::*:***:. :. * * .: . . . : * *:*****:::*** * **:::. ::* ...* . :* : : *** *: ****::* :: * ::. :.::* :: :: : : * : * **..* : . : ::* . :: *. * *::*.*****:: : . : : . : : : : . :. : . :: . : . .. : * ::.: ::: :* ***: *. .* ..: . ** * : . :: ::* :: .: . .. . *:: ", "identical_positions": 60, "similar_positions": 125, "identity": "7.88%" }, { "cls_id": "homologset.agr.RGD:1308690", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZZK6-1", "uniprot_id": "D3ZZK6_RAT", "id": "D3ZZK6-1", "name": "", "aln": "MRRPRRLKSDWKLS----TEPREPGARPALLQAMMILRFIALALVTGHVGGETRIIKGYECRPHSQPWQVALFQK-------TRLLCGATLIAPKWLLTAAHCRKP----------HYVILLGEHN-LEKTDGCEQRRMATESFPHPGFNNSLPNKD-HRNDIMLVKMSSPAFITRAVRPLTLSSLCVTAGTSCLISGWGTTSSPQLRLPHSLRCANVSIIGHKECERAYPGNITDTMLCASVRKEGKDSCQGDSGGPLVCNGSLQGIISWGQDPCAVTRKPGVYTKVCKYFDWIHEVMRNN-------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QYN3-1", "uniprot_id": "KLK11_MOUSE", "id": "Q9QYN3-1", "name": "Kallikrein-11", "aln": "MRR---LKSDWKLS----TETREPGARPALLQARMILRLIALALVTGHVGGETRIIKGYECRPHSQPWQVALFQK-------TRLLCGATLIAPKWLLTAAHCRKP----------HYVILLGEHN-LEKTDGCEQRRMATESFPHPDFNNSLPNKD-HRNDIMLVKMSSPVFFTRAVQPLTLSPHCVAAGTSCLISGWGTTSSPQLRLPHSLRCANVSIIEHKECEKAYPGNITDTMLCASVRKEGKDSCQGDSGGPLVCNGSLQGIISWGQDPCAVTRKPGVYTKVCKYFNWIHEVMRNN-------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UBX7-2", "uniprot_id": "KLK11_HUMAN", "id": "Q9UBX7-2", "name": "Kallikrein-11", "aln": "MQR-LRWLRDWKSSGRGLTAAKEPGARSSPLQAMRILQLILLALATGLVGGETRIIKGFECKPHSQPWQAALFEK-------TRLLCGATLIAPRWLLTAAHCLKP----------RYIVHLGQHN-LQKEEGCEQTRTATESFPHPGFNNSLPNKD-HRNDIMLVKMASPVSITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPGNITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKYVDWIQETMKNN-------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W586-1", "uniprot_id": "Q9W586_DROME", "id": "Q9W586-1", "name": "trypsin", "aln": "-------MTQFGLHG---------------CSYILFWFLLACAAADLQENQQSRIINGSVAKADETRHLVSIRLLRHDNNFGSGHICGGALIAPRKVLTAAHCLYNNQRKRFRRASEFVVVLGTLNRFEHRNGTIVSQVSSMAYMHTFSPDSMRDDVGILFLRTGLPMSPGGGVHLTVAPIQLAGQITPPGKLCQVAGWGRTE--QSSLSNILLTANVSTIRHQTCRMIYRSGLLPGMMCAGRLQGGTDSCQGDSGGPLVHEGRLVGVVSWGYG-CAEPGLPGVYVDVEYYRQWIEGRSGAPHSRLATGLFLLLLLPLLMRCSGSWL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: . : :: * . . ::***:* .:... .:: : :**.:****: :****** .::: ** * ::: :* : :: :: *. :*: :. : *:. . :* *: *: ...*. * ::*** *. * *.: * **:: * *: *. * ..: *:**. : *.************ : * *::*** . ** . ****..* * :**. ", "identical_positions": 73, "similar_positions": 79, "identity": "22.32%" }, { "cls_id": "homologset.agr.RGD:1308691", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XIG6-1", "uniprot_id": "GALK2_RAT", "id": "Q5XIG6-1", "name": "N-acetylgalactosamine kinase", "aln": "----------MAAEDPATRRVQVAEHPRLLKLKEMFNSKFGSTPKFYVRAPGRVNIIGEHIDYCGYSVLPMAVEQDMLIAVGPV--KTQTLQLANTDPLYP----DFSTTANNICIDKTQPLWHNYFLCGFKGIQ--------EHFGLTQLPGMNCLVDGNIPPSSGLSSSSALVCCAGLVTLTVLG---MRLSKVELAEICAKSERYIGTEGGGMDQSISFLAEEGTAKLIEFSP-LRATDVKLPSG----AVFVIANSCVEMN--KAATSHFNVRVMECRLAAKVLAKHKGLQWDK-------------------VLRLEEVQSELG-------ISLEEMLLVTEDALHAEP--YSREEICKCLGISLEELRTQILSPNTQGELTFKLYQRAKHVYSEAARVLQFKQVCEAAP----DNAVQLLGELMNQSHRSCRDMYECSCPELDQLVDICRKFGAKGSRLTGAGWGGCTVSLVP---ADTLSSFLASVHEAYYQGNMSRLAREKHS--LFATKPGGGALVFLEA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q68FH4-1", "uniprot_id": "GALK2_MOUSE", "id": "Q68FH4-1", "name": "N-acetylgalactosamine kinase", "aln": "----------MAAEDPATRRVQVAEHPRLLKLKEMFNSKFGSTPKFYVRAPGRVNIIGEHIDYCGYSVIPMAVEQDMLIAVEPV--KTHTLQLANTDPLYP----DFSTTANNICIDKTKPLWHNYFLCGFKGIQ--------EHFGLSKLPGMNCLVDGNIPPSSGLSSSSALVCCAGLVTLTVLG---LRLSKVELAEICAKSERYIGTEGGGMDQSISFLAEEGTAKLIEFSP-LRATNVKLPSG----AVFVIANSCMEMN--KAATSHFNVRVMECRLAAKVLAKHKGLQWDN-------------------VLRLEEVQSKLG-------ISLEEMLLVTEDALHPEP--YSREEICRCLGISLERLRTQILTPNTQDELTFKLYQRAKHVYSEAARVLQFKQVCEDAP----DNAVQLLGELMNQSHRSCRDMYECSCPELDQLVDICRKFGAKGSRLTGAGWGGCTVSLVP---ADMLSSFLASVHEAYYQGNTSRLAQEKHS--LFATKPGGGALVFREV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q01415-1", "uniprot_id": "GALK2_HUMAN", "id": "Q01415-1", "name": "N-acetylgalactosamine kinase", "aln": "----------MATESPATRRVQVAEHPRLLKLKEMFNSKFGSIPKFYVRAPGRVNIIGEHIDYCGYSVLPMAVEQDVLIAVEPV--KTYALQLANTNPLYP----DFSTSANNIQIDKTKPLWHNYFLCGLKGIQ--------EHFGLSNLTGMNCLVDGNIPPSSGLSSSSALVCCAGLVTLTVLG---RNLSKVELAEICAKSERYIGTEGGGMDQSISFLAEEGTAKLIEFSP-LRATDVKLPSG----AVFVIANSCVEMN--KAATSHFNIRVMECRLAAKLLAKYKSLQWDK-------------------VLRLEEVQAKLG-------ISLEEMLLVTEDALHPEP--YNPEEICRCLGISLEELRTQILSPNTQDVLIFKLYQRAKHVYSEAARVLQFKKICEEAP----ENMVQLLGELMNQSHMSCRDMYECSCPELDQLVDICRKFGAQGSRLTGAGWGGCTVSMVP---ADKLPSFLANVHKAYYQRSDGSLAPEKQS--LFATKPGGGALVLLEA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P13045-1", "uniprot_id": "GAL3_YEAST", "id": "P13045-1", "name": "Protein GAL3", "aln": "MNTN------VPIFSSPVRDLPRSFEQKHLAVVDAFFQTYHVKPDFIARSPGRVNLIGEHIDYCDFSVLPLAIDVDMLCAVKILDEKNPSITLTNADPKFAQRKFDLPLDGSYMAIDPSVSEWSNYFKCGLHVAHSYLKKIAPERFNNTPLVGAQIFCQSDIPTGGGLSS--AFTCAAALATIRANMGKNFDISKKDLTRITAVAEHYVGVNNGGMDQATSVYGEEDHALYVEFRPKLKATPFKFPQLKNHEISFVIANTLVKSNKFETAPTNYNLRVIEVTVAANALATRYSVALPSHKDNSNSERGNLRDFMDAYYARYENQAQPWNGDIGTGIERLLKMLQLVEESFSRKKSGFTVHEASTALNCSREEFTRDYLTTFPVRFQVLKLYQRAKHVYSESLRVLKALKMMTSATFHTDEDFFTDFGRLMNESQASCDKLYECSCIETNQICSIALANGSFGSRLTGAGWGGCTIHLVPSGANGNVEQVRKALIEKFYNVRYPDLTDEELKDAIIVSKPALGTCLYEQ-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P04385-1", "uniprot_id": "GAL1_YEAST", "id": "P04385-1", "name": "Galactokinase", "aln": "MTKSHSEEVIVPEFNSSAKELPRPLAEKCPSIIKKFISAYDAKPDFVARSPGRVNLIGEHIDYCDFSVLPLAIDFDMLCAVKVLNEKNPSITLINADPKFAQRKFDLPLDGSYVTIDPSVSDWSNYFKCGLHVAHSFLKKLAPERFASAPLAGLQVFCEGDVPTGSGLSSSAAFICAVALAVVKANMGPGYHMSKQNLMRITVVAEHYVGVNNGGMDQAASVCGEEDHALYVEFKPQLKATPFKFPQLKNHEISFVIANTLVVSNKFETAPTNYNLRVVEVTTAANVLAATYGVVLLSGKEGSSTNKGNLRDFMNVYYARYHNISTPWNGDIESGIERLTKMLVLVEESLANKKQGFSVDDVAQSLNCSREEFTRDYLTTSPVRFQVLKLYQRAKHVYSESLRVLKAVKLMTTASFTADEDFFKQFGALMNESQASCDKLYECSCPEIDKICSIALSNGSYGSRLTGAGWGGCTVHLVPGGPNGNIEKVKEALANEFYKVKYPKITDAELENAIIVSKPALGSCLYEL-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. ....: : . : : . * . : *.* .*:*****:********.:**:*:*:: *:* ** : *. :: * *::* :. *:. .. : ** : . * *** **:: : *:* : * * : : :.::*...**** *: *...*..: . :** :* .* . :*:*:*.:.*****: *. .**. * :** * *:** .*:*. *****: : * ::*.:::*:**:* **: ** .: . * .: . * :** :.*::: : :. .: . .*. * *.: : *:. . :************: ***: :: *. :: . :* ***:*: ** .:***** * ::: .*. *: *************: :** . : .. : : :*: :: : . ::.:**. *: : ", "identical_positions": 148, "similar_positions": 159, "identity": "27.98%" }, { "cls_id": "homologset.agr.RGD:1308692", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JTY4-1", "uniprot_id": "NFAC3_RAT", "id": "A0A0G2JTY4-1", "name": "Nuclear factor of activated T-cells, cytoplasmic 3", "aln": "MTTANCGAHDELDFKLVFGEDGAPTPVSQVSRPADLEPDDCASIYIFNVDPPPSTLNSSLGLPHHGLLQSHSSVLSPSFQLQGFKNYEGTDDISESKYSSLSGPKPFECPSIQITSISPNCHQETDAHEDDLHVNDPEREYLERPSRDHLYLPLEPSYRE-SSLSPSPASSVSSRSWFSDASSCESLSHIYDDVDSELNEAAARFTLGSPLTSPGGSPG--------------------GCP------GEESWH--QQYGPG---HSLSPRQSPCHSPRSSITDENWLSPRPASG---PSSRPTSPCGKRRHSSAEVCYAGSLSPHHSPVPSPGHSPRGSVTEDTWLTAPVHTGSGLSPAPFPFQYCVETDIPLKTRKT-----SDDQAAILPGKLEVCSDDQGSLSPSRETSVDDGLGSQYPLKKDSSGDQFLSVPSPFTWSKPKPGHTPIFRTSSLPPLDWPLPTHFGQCELKIEVQPKTHHRAHYETEGSRGAVKASTGGHPVVKLLGYSEKPINLQMFIGTADDRYLRPHAFYQVHRITGKTVATASQEIIIASTKVLEIPLLPENNMSASIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHIPQPSGKVLSLQIASIPVECSQRSAQELPHIEKYSINSCSVNGGHEMIVTGSNFLPESKIIFLEKGQDGRPHWEAEGKIIREKCQGGHIVLEVPPYHNPAVTSAVQVHFYLCNGKRKKSQSQRFTYTPVLMKQEQREDTDLSSVPSLPVPHSAQTQRPSSDTGHPHDSALSAPRSLICPVQPAYASMITSTHLPQLQCRDEGAGKEQHIIPSSVMHQPFQVTPTSPMGSSYQSIQTN-MYNGPTCLPMNPASSQEFDPVLFQQDAALSNLVNLGCQPLSPIPFHSSNSDATGHLLAHSPHSVQTPPHLQSMGYHCSSAGQRSLSSPVAAQVTGQPSSHLQPITYCPSHPGSATAASPAASHALSSSPISGPPSPQLQSMPYQSPSSGTASSPSPVTRMHSGQHSTQAQSTGQGGLSVPSSLVCHSLCDPASFPPGGAAVSIKPEPEDQEPNFATIGLQDITLDDVNEIIGRDMSQITVSQGPEVIRDAPLPGPESPDVMSSNSAQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97305-1", "uniprot_id": "NFAC3_MOUSE", "id": "P97305-1", "name": "Nuclear factor of activated T-cells, cytoplasmic 3", "aln": "MTTANCGAHDELDFKLVFGEDGAPAPPPPGSRPADLEPDDCASIYIFNVDPPPSTLTTPLCLPHHG-LPSHSSVLSPSFQLQSHKNYEGTCEIPESKYSPLGGPKPFECPSIQFTSISPNCQQELDAHEDDLQINDPEREFLERPSRDHLYLPLEPSYRE-SSLSPSPASSISSRSWFSDASSCESLSHIYDDVDSELNEAAARFTLGSPLTSPGGSPG--------------------GCP------GEESWH--QQYGSG---HSLSPRQSPCHSPRSSITDENWLSPRPASG---PSSRPTSPCGKRRHSSAEVCYAGSLSPHHSPVPSPGHSPRGSVTEDTWLTAPVHTGSGLSPAPFPFQYCVETDIPLKTRKT-----SEDQAAILPGKLEICSDDQGNLSPSRETSVDDGLGSQYPLKKDSSGDQFLSVPSPFTWSKPKPGHTPIFRTSSLPPLDWPLPTHFGQCELKIEVQPKTHHRAHYETEGSRGAVKASTGGHPVVKLLGYSEKPINLQMFIGTADDRYLRPHAFYQVHRITGKTVATASQEIIIASTKVLEIPLLPENNMSASIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHIPQPSGKVLSLQIASIPVECSQRSAQELPHIEKYSINSCSVNGGHEMIVTGSNFLPESKIIFLEKGQDGGPHWEVEGKIIREKCQGAHIVLEVPPYHNPAVTSAVQVHFYLCNGKRKKSQSQRFTYTPVLMKQEQREDTDLPSVPSLPVPHSAQAQRPSSETGHPHDRAMSAPGGLLCQVQPAYTSMVASTHLPQLQCRDEGAGKEQHIATSSVMHQPFQVTPTSPIGSSYQSIQTS-MYNGPTCLPVNPASSQEFDPVLFQQDAALSSLVNLGCQPLSPIPFHSSNSDATGHLLAHSPHSVQTPPHLQSMGYHCSNAGQTALSSPVADQITGQPSSHLQPITYCPSHPGSATAASPAASHPLASSPISGPSSPQLQPMPYQSPSSGTASSPSPTTRMHSGQHSTQAQSTGQGGLSVPSSLVCHSLCDPASFPPGGATVSIKPEPEDQEPNFATIGLQDITLDDVNEIIGRDMSQISVSQATEVMRDTPLPGPASPDLMTSHSAH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q12968-1", "uniprot_id": "NFAC3_HUMAN", "id": "Q12968-1", "name": "Nuclear factor of activated T-cells, cytoplasmic 3", "aln": "MTTANCGAHDELDFKLVFGEDGAPAPPPPGSRPADLEPDDCASIYIFNVDPPPSTLTTPLCLPHHG-LPSHSSVLSPSFQLQSHKNYEGTCEIPESKYSPLGGPKPFECPSIQITSISPNCHQELDAHEDDLQINDPEREFLERPSRDHLYLPLEPSYRE-SSLSPSPASSISSRSWFSDASSCESLSHIYDDVDSELNEAAARFTLGSPLTSPGGSPG--------------------GCP------GEETWH--QQYGLG---HSLSPRQSPCHSPRSSVTDENWLSPRPASG---PSSRPTSPCGKRRHSSAEVCYAGSLSPHHSPVPSPGHSPRGSVTEDTWLNASVHGGSGLGPAVFPFQYCVETDIPLKTRKT-----SEDQAAILPGKLELCSDDQGSLSPARETSIDDGLGSQYPLKKDSCGDQFLSVPSPFTWSKPKPGHTPIFRTSSLPPLDWPLPAHFGQCELKIEVQPKTHHRAHYETEGSRGAVKASTGGHPVVKLLGYNEKPINLQMFIGTADDRYLRPHAFYQVHRITGKTVATASQEIIIASTKVLEIPLLPENNMSASIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHIPQPSGKVLSLQIASIPVECSQRSAQELPHIEKYSINSCSVNGGHEMVVTGSNFLPESKIIFLEKGQDGRPQWEVEGKIIREKCQGAHIVLEVPPYHNPAVTAAVQVHFYLCNGKRKKSQSQRFTYTPVLMKQEHREEIDLSSVPSLPVPHPAQTQRPSSDSGCSHDSVLSGQRSLICSIPQTYASMVTSSHLPQLQCRDESVSKEQHMIPSPIVHQPFQVTPTPPVGSSYQPMQTNVVYNGPTCLPINAASSQEFDSVLFQQDATLSGLVNLGCQPLSSIPFHSSNSGSTGHLLAHTPHSVHTLPHLQSMGYHCSNTGQRSLSSPVADQITGQPSSQLQPITYGPSHSGSATTASPAASHPLASSPLSGPPSPQLQPMPYQSPSSGTASSPSPATRMHSGQHSTQAQSTGQGGLSAPSSLICHSLCDPASFPPDGATVSIKPEPEDREPNFATIGLQDITLDDVNEIIGRDMSQISVSQGAGVSRQAPLPSPESLDLGRSDGL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58IZ64-1", "uniprot_id": "A0AC58IZ64_DANRE", "id": "A0AC58IZ64-1", "name": "", "aln": "MSSNYS---EELDFRLIFGESSFSHTESRSDDDANCYP-LYPSEPHFPTEQQDNCTNQPYGTPNPG---SVQPMESPS--------------------------RVFDCPSIQITSIPANCLQDPGTQQLDQSTGACAEVGAGSLSRDQLFLPLDASYRDTSSLCPSPCSSLSSRSWLSDASSCESFSHIYDDVEAELNEAAAQVRLASPLVSPLPSPLPSPLNSPQASPQVSPLVSPFGSPGCMAAYGDDPWYRYQQYHQQSLQYPFAQSLSPYQSPRTSITEETWLSPRPHSSSSRPSSRPTSPCGKRRHSSAEVIPG-LASPHLSPNATPSHSPRGSVTEESWMGGATFAPYHTLP--------VDVDVPSKTRRTYQANHNQDQASLFSGQEDSGLQDQGLANSGIAVSLPS-------LKKEDIVEHFLAVPTPFSWVKPKQAST-LYRSTSLPPLDCPLPSQYGQCELKMEIQPRAHHRAHYETEGSRGAIKSECGRHPVVKLIGYNEKPVSLQMFIGTADERYIRPHPFYQVHRITGKTVATPSQDTVISNTKVLEIPLLPENNMCASIDCAGILKLRNSDIELRKGETDIGRKNTRVRAVFRVNIPQHNGKLLSLQVASSPIECSQRLAQELPQVESFSPACGSASGGEEMRITGQNLNSESTVVFLEKGSDGKTQWEVNVRPLPEKSQNTSIVVKIPPYYKKTTASSTQVQFYVTNGKRKRSGSQFFTFLSAQVKQEFS----------------TQPAAPSGQTELLEQWLLSEET--LCASTHLSFSPQDASYLSRSHPADRSFN------SRTDLHSMFPSSLIEFNSSLYQKPHQDPSYKAQPSLPVAFPEQT-------------ATQLDKGYQCIRSQNLDNLILDASG---LHTMAAVSIPQSSSSQGLPTVSKVPSTSPSTSKNAEPASASLVESSEQYCVSENGDRLNIKEEPEEEKE---------LDFQSVGLQDITLDDGKTIDLITVKTLTLNTLDLTCTHR----HHTCTVHQESVDIRKFKTQFIYVEIQFLNKER-----SKSVNSAQCSGVTGRHEQKLCYFCCSPG----RYQWCSGLENP---------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:: . :****:*:***.. . . . . *: * .* * .: . . . *: * * ..: *** : *:*****:***..** *: .::: * . . ***:*:***:.***: ***.***.**:*****:********:*******::*******:. *.***.** ** *.* *::.*: *** :.:: ** :***:*:*:*.****** *. ******************* . *** ** .:*.*********::*: .... * *:.*:* ***:* .:***:::.*: : :*** ... .*: . ***:. ::**:**:**:* *** . * ::*::****** ***:::******:*:**::**************:*:. * ******:**.***:.*********:**:***.**************.**: :*:.**************.********************************* ****:*** .**:****:** *:***** *****::*.:* . *..**.** :**.*: .**.::*****.** .:**.: : : **.*. **:::***:: :.:::.**:**: *****:* ** **: .. :*** :*. **.:: .: :* :* * :::*.: : *.. . . . :*. * : .* ** : . *:. ..**: ... : :: * * : . :.. .::* *: :* .* * . : .*. ....* .. * *. *. . ... ::*.: *. : . ..: . * :: : .* : :. : :. * .* . *.*: ::: : .::. ..*. :.:. : * . * .. . ", "identical_positions": 407, "similar_positions": 287, "identity": "36.44%" }, { "cls_id": "homologset.agr.RGD:1308693", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A600-1", "uniprot_id": "A0A8I6A600_RAT", "id": "A0A8I6A600-1", "name": "DnaJ homolog subfamily C member 4", "aln": "MDFWGPPFPSCPPAVVMPSLLLRLPLRLCRLWPCSPPTRLLTAATGQRPVPTNYYELLGVHPGASAEEIKRAFFTKSKELHPDRDP--GNPALHSRFVELSEAYRVLSREESRRNYDHQLHSASPSKSSGSTAEPKYKQQTHSSPWETPNAEYWAQFHSVRPQEPESRKQQHKHNQRVLGYCLLLMVAGMGLHYVAFRKLEQVHRSFMDEKDRIITAIYNDTRARARANRARIQQKHQ---QRQPP-TEPSLPPESSRIMPQDTSQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D844-1", "uniprot_id": "DNJC4_MOUSE", "id": "Q9D844-1", "name": "DnaJ homolog subfamily C member 4", "aln": "----------------MPSLLLQLPLRLCRLWPHSLSIRLLTAATGQRSVPTNYYELLGVHPGASAEEIKRAFFTKSKELHPDRDP--GNPALHSRFVELNEAYRVLSREESRRNYDHQLHSASPPKSSGSTAEPKYTQQTHSS-WEPPNAQYWAQFHSVRPQGPESRKQQRKHNQRVLGYCLLLMVAGMGLHYVAFRKLEQVHRSFMDEKDRIITAIYNDTRARARANRARIQQERQ---QRQQPRAEPSLPPESSRIMPQDTSP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NNZ3-1", "uniprot_id": "DNJC4_HUMAN", "id": "Q9NNZ3-1", "name": "DnaJ homolog subfamily C member 4", "aln": "----------------MPPLL---PLRLCRLWPRNPPSRLLGAAAGQRSRPSTYYELLGVHPGASTEEVKRAFFSKSKELHPDRDP--GNPSLHSRFVELSEAYRVLSREQSRRSYDDQLRSGSPPKSPRTTVHDKSAHQTHSS-WTPPNAQYWSQFHSVRPQGPQLRQQQHKQNKQVLGYCLLLMLAGMGLHYIAFRKVKQMHLNFMDEKDRIITAFYNEARARARANRGILQQERQRLGQRQPPPSEPTQGPE---IVPRGAGP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P92029-1", "uniprot_id": "DNJ60_DROME", "id": "P92029-1", "name": "DnaJ-like protein 60", "aln": "---------------------------MLRLCLPTRAGYVRNFSNDKPRKPETHYEVLNIRNDCSTREVRNAFVQLSKLYHPDVKSNAACPERTARFVQISEAYKTLIKPERRRDYDDSLLWQ-PSRSDRSPVG-ETVNPGQAWDVRPNYDPNPGPYYGIRG-------LKRVSNWQVAVVLMALGFVGALFGFTSVRSSFKLSRQIQDEISAEANSHHAAVVADAQKYGNEEQVRRMVDRMSRSPFNQSSAK-------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ** . . : : .: * .:**:*.:: ..*:.*::.**. ** *** .. . * :***::.***:.* : : **.**..* *.:* :.. : : :: . . ::.:* :: * :* : * ..* : : :.*. :: .: ** . .: : . * *: * .: : * :.: ", "identical_positions": 42, "similar_positions": 77, "identity": "15.79%" }, { "cls_id": "homologset.agr.RGD:1308694", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4AE70-1", "uniprot_id": "D4AE70_RAT", "id": "D4AE70-1", "name": "", "aln": "MADELSRVGKETCSEQVRRSHVSGPCSQFQRRFIQRVSLLRKLPTRFVLHPERKQKVAALPGNDQEAMKCLPEGDLDHCLLSKMDLRQQQISQTVEEVQKIVHLLTTEISHHDSRFEAVPASDTYNDSIK------------------------VLAPSLFHVTVPLRGLAGYKGVRTPRWRYYSLQGTKLSCPLRDPEGLQQWLETETFMKTLWQWHKVDVNIEGDIVPAKVLQIFQMLVENAVRTCHLSGKVTVLEKR-TTVWVAVETSTGQVELELAPTVEIPTTWPEKAQWPRCLKRWPSPERVECIKSFGFNLVAQSTYHWQLSFSQAERVLCEQLDEDGGCRRRCFQVLRQLKEDVWCPGRRPVITTHHLQTVLFWTCEKYPHLKDWQVFHQAFLRLVRKLHRCVSQHFLKHYFVPKSNLFQSANPSELDAVAQKVAFFLKNPQLELP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CI17-1", "uniprot_id": "MB213_MOUSE", "id": "Q8CI17-1", "name": "Protein mab-21-like 3", "aln": "MADEFFHAGKENCSEQARRSQVSGPRSQFQRSFIQRVTLLGKLPTRFVLHRERKQKVAAILGVDQEAMKSLPEGDLDHCLLSKVDLRRQQISQTMEEVQKIIHLLTTEISRQDSRFEAVPVSDTHNESIK------------------------VLAPSLFHVTVPLKGLAGYKGVQRQRWRYYNVQGAKLTCPLRDPEGLQQWLETEMFMKTLWQWHKADVNIEGDIVPAKVLQVFRTLVENAVRTCHLSGKVTVLEKR-TTVWVAMETSTGQVELELAPTVEIPTTWPEKAQWPRCLKRWPSPERVECIKSFGFNLVAQSAYHWQLSFSQAEQVLFEQLDEDGGCRRQCFQVLRQLKEDVWCPGRRPVITTHHLQTVLFWTCEKYPHLKDWQVFHQALLRLVRKLHRCVSQHFLKHYFVPKSNLLQSANPSELDAVAQKVAFFLKNPQVELP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N8X9-1", "uniprot_id": "MB213_HUMAN", "id": "Q8N8X9-1", "name": "Protein mab-21-like 3", "aln": "-------------------------------------------------------------------MKYLTVGDLEDCLLNKVDLRRQQISQAVEEVQKVVHHLTTNISNQDIRFQAVPYSDTYNENIK------------------------VLAPSQFLVTVPIKGLAGYREAREQHWRYYTLQGTRLPCPLRDPEGLQQWLEVEQFMKSLWQWHETDVNIDGDIVPAKVLLVFRKLVENAVRTCHLSGKVSLLGNR-SAVWVAVETSAYQVELELVPAVEIPTTWSKKARWPRCLQRWPSQERVECIKSFGFNLLACSNYHWQLSFLRAEQVLLEQLDEDGGCRRKCFQVMRHLKEDIWCPGNRPVITSHHLQTVLFWTCEKYPHFKDWQVFSKAFLRLVRKLHKCVSQHFLKHYFVRNSNLFQCTNPTELDTVAQKLATFLKNPQIGPP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8E4S7-1", "uniprot_id": "MB213_DANRE", "id": "A8E4S7-1", "name": "Protein mab-21-like 3", "aln": "-------------------------------------------------------------------MTNCTDEDLDNYLLNQVDLRHRQVSKCVEDVQKIIKDLTTEVSSKDARFQSIANAGVHNASLKDQPALMSKWSALLRGRCAYNPAIQVLSPTLYLISVPLQGLMGYKERRTRQWRYYTLTGSRLLSPVREPEKLHQWLELESFVNPSQEWHDARMTIEGDIVPAKVVNVFKDLLETSIKTRGLTNKVSVLESVGTAVRVAVETSEAQIEVKLVPTVELMNYWPKRARWPRLFRRWPSTERARCIKSFGFNLMASSNYHWLLSFSRAEQVLLSNIDEDGGCRRKCYRVVRQLKEDGWCPGSKPVITAFHLQTLLFWTCEKYPCTRDWKDFRGCVLRLVQKLHKCVSQHYLRHYFIRSHNLLKYSNTNELDEVAKKINHFLENPGTYIH", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. . **:. **.::***::*:*: :*:***::: ***::* :* **:::. :..:* .:* **:*: : ::**::** **: : :****.: *::* .*:*:** *:**** * *::. :**.. :.*:********: :*: *:*.:::* *:.**::* . ::* **:*** *:*::*.*:**: . *.::*:*** ::**** **..*********:* * *** *** :**:** .::********:*::*:*:**** **** :****:.****:********* :**: * ..****:***:*****:*:***: . **:: :*..*** **:*: **:** ", "identical_positions": 180, "similar_positions": 120, "identity": "39.65%" }, { "cls_id": "homologset.agr.RGD:1308695", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZHR0-1", "uniprot_id": "D3ZHR0_RAT", "id": "D3ZHR0-1", "name": "Transcriptional protein SWT1", "aln": "---MLLCTTSAHKLETVYDHKFPKMSIKESCGKEEKSQKK-QTTSSPTFDEDKKEGE-------------ISAGSTSSEHCVKPVSTKKRKLKPDDTDIVYYNTNRKHSMKRLNVEVGLPKKRPKFSSSTQ------VASYLNSNQITLHSSSSDGAK-------DTKLKDCKLTNIGSKLDYEIKSRSL----------------IKITKDMKSKAEDQTKE--KNWPSLLIQK-KMKELKKEKNN--KDSSE---------ELEKCTKNQPPQNYNFSNIIKEPLESGRKKIS---FKIPKKSSSALQKLAEENIFSVDSSKSKSKQEGKEHLQSHRVS------LSLERHKTENLFSESTHKHTVCER------RREYHLEHQETNGSDSKENCAQSFETPCSSVSSETIQDTDEEMQIVEELHAARVGKSVDLPAGPPSGELMSMEIDLVEDDVHSSADILSNTASDKKLLIVIDTNILMNHLKFVRILKTTEIPGFDTLVLIIPWVVMQELDRMK-AGKLLKHVQHKAVPAIHFINDSLKSQDRKLWGQSLQLASQKLYGLSDEN-------NDDRVLKCCLQYQELFPCSLVILCTDDRNLRSKGLISGVKSLSKEELDTEILNLTLNTDLCHQPYISKQ-QLKAEVPPTEETSKEESTNSGLSILLER-----IICDLEKCLGTALSSILETEMKIAFGNLWMEVLYLKPPWTLIN-LLQCFKKHWLAVFGLVMENNLLVTIESLYDNLSKANKAVDFTTVKFLLQDSKSLLHAFSTRSNYDGILPQTFAQVNKLLQVLAEVKTKLKPNSSESTMSKKQEDT-LMKLHNQEVTVFLDSHPPQFTRHQEIWSVLENVWTSIYQNSTDVFQTLDSSSTLTTSKIAS----FEEAFIYLQKLMVAVKDILEGIQRILAPNSNCQDVETLYNFLIKYEVN-KNVRFTAQELYDCVSQTEYREKLTIGCRQLIEMEYTMQQCSASVYMEAASRGWCEGMLNSRT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DBQ9-1", "uniprot_id": "SWT1_MOUSE", "id": "Q9DBQ9-1", "name": "Transcriptional protein SWT1", "aln": "---MLLCTTSAHKLETVYDHKFLKMSIKESCAKEEKSQKK-QTISSPTFNEDKKKGE-------------ISAGSTSSEHGVQPVSTKKRKLKADDTDNVYYNANRKNS-KRLNVEVFIPKKRLKFSSSTQ------AVSYLNNNQMTSHSCSSNGTK-------DTKVKDCKLTNIGSKLNYEIKNHSR----------------IKITKDMKSKPVDQTKE--KNWPSLLIQK-KMKELKKEKNN--KDSSE---------ELEKCKKNHLPQNYNFSNMIKESFESGRKKIS---FKIPKKSSTTLQKLVEEKIFTIDSSKSKSKQEEKQHLQSHQMS------LNLARHKTENSFSDSTHKQSVCER------IRKDHCEHQGTSSSDSKENHAQSFETPCSSVSSEDTQDADEEMQIVEELHAARVGRSVDLPVVPPSGELMSMEIDLVDEDAHPSA---AHTASDTKLLIVMDTNVLMNHLKFVKILKTTEIPGFDTLVLIIPWVVIQELDRMK-AGKLLKHVQHKAVPAIHFINNSLKSQDRKLWGQSLQLASQKLYGLSDEN-------NDDRVLKCCLQYQQLFPCSLVILCTDDRNLRTKGLISGVKSLSKEDLDTEILNLTLNTDLCHQPCISKQ-QLNAEVPPAKETPKEGAANSGLSILLER-----IICDLEKCLGTALSSILETEMKIAFGNLWMEVLYLKPPWTLIN-LLQCFKKHWLAVFGLVMENNLLVTVESLYENLCKANKAVDFTTVKFLLQDSKSLLHAFSTRSNYDGVLPQTFAQVNKLLQVLAEVKTKLKPSSSESTRSKEQEDTSLVKLHNQDVNVFLDSNLPQATRHQEIWSVLESVWMSIYQNSTDVFQTLDSSSTLTTSKIAS----FEEAFVYLQKLMVAVKDILEGIQRILAPNSNYQDVETLYNFLIKYEVN-KNVKFTARELYDCVSQTEYRERLTIGCRQLIEMECTMQQCSASVYMEARSRGWCEDMLNNRP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5T5J6-1", "uniprot_id": "SWT1_HUMAN", "id": "Q5T5J6-1", "name": "Transcriptional protein SWT1", "aln": "------------------------MSSKESCGKKETSQRKDTTTSSPNFGEKDKKER-------------KTPASSTSSSSIRSVSSEKRKLKSDHTDVLYYNIKRRQGLKRLSVEIDTLRRRPKIGSSSQRPIKLKEASYSNDNQIILQSPSSNGTKKDIHKCVDFKPKDIKLTNAGSKLDHGIKSLSS----------------PKIASDVKPKAEGQASE--NKWSHLLVQREKMKELKKGRNSKFRDNSEK-------CVLEKWKRNQFSQDYNSNKIIKEPLGSRRQKIS---FKIPIKSRDTLQKLVEENVFNIDSNNSKTKQEEREYLESSQVS------LNVTRQKTEHLLSDFTYKRTVHEW------KRKHHYDHQESNDSHSRENLTQSFEAPCCSVSSESIQDADQEMQIVEELHAARVGKSVDLP-----GELMSMEIDL-EDDVHSSS---ANNTSDRKLLIVIDTNILMNHLKFVRILKTTEVPGFDKLVLIIPWVVMQELDRMK-EGKLLKRAQHKAIPAVHFINDSLKNQDRKLWGQSIQLASQKHYGLSDEN-------NDDRVLKCCLQHQELFPCSFVILCTDDRNLRNKGLISGVKSLSKEELSAELLHLSLNTDVCHQPCIPKQ-QLKAETTPLKESYKEESTNSGLSILLES-----IVSDLEKSLGTGLSSILETEMKIAFGNLWMEILYLKPPWTLLH-LLQCFKKHWLAVFGLVMEKNLLLTIESLYKNLRKANKAVDFTTVKFLLQDSRSLLHAFSTRSNYDGILPQTFAQVNNLLQTFAEVKTKLKPNSSENTVTKKQEGTSLKNSHNQEITVFSSSHLPQPSRHQEIWSILESVWITIYQNSTDVFQRLGSNSALTTSNIAS----FEEAFICLQKLMAAVRDILEGIQRILAPNSNYQDVETLYNFLIKYEVN-KNVKFTAQEIYDCVSQTEYREKLTIGCRQLVEMEYTMQQCNASVYMEAKNRGWCEDMLNYRI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9P2Z5-1", "uniprot_id": "A0A8M9P2Z5_DANRE", "id": "A0A8M9P2Z5-1", "name": "Transcriptional protein SWT1", "aln": "MASKKSKKKKNKKEEKLSSRLYEDEKEERDTKRCISSKSKHKHHHCVSFDKDEAKGRRATVSLPEKTFEAILNQTDAGESKSKKKRSKINKNKGTEKSKPVLNLPNKHEKKCVNAKDKHKNASPQISKNKAKNQPSSEEASKKREKLVSRKPPSEDLRWTLAKDDCLKLQQRRMKPVKRRLSQELHAQPKRRNIKNGTDVAQTNCQFKSPTEMRKKLVGKRSKKINQPAGAILQNSPGKTMKNNSKAAMSAVKHVRSKLKLLEDISPKKKDRAKQRKTLGVLLGEKSPSFCGSIANTKFKIP-KLPSAVKAQTNTNLFNVNSSDSRTQITTQPSLPGSSPAKPQNFLLRQQMQKPEEVSSQTSYELSSLCSSHHSYVSRQVQLVYTDDKGEVTMTDGASHNDQHISSQKAPKTYDFDHEVHLVEELNLARSERRLEVNVEQNCGELTCMDIDPPEEGANTIL-------KKQALLIVLDTNVLLSHLEFVKKIRSRGFGGLGFPTLLIPWVVLQELDYLK-SGKLSSKVEDKARPAVHYIYSCLKNQEPRLIGQSMQLASQADCGPGVVN-------NDDRVLQCCLQYQALYPEGALVLCTNDKNLCSKALLSGVKAYSKADLVIEAEGTTSKIFEPDQQYICARPAVMSPAGPVEKAEKQGSQDNSNSIVVDEQDLIEYVSLLESSLQAALSEVLTEEMKAAYGDLWIEIVYVKPPWSLEG-LLKCFKKHWIAVFGLIINRSLLSCVEMLSDCLCSD-RSVEHTSILSAVSLAKELLSALSGRSQYSGHVAHALSTLHTLQQRLQSPKALLESGEADNE-------------DSLMAEIEDDVALPPSTSHQEVWALFESIWNNVCQISSSLFSALHYTPGTTEPSLRSTSPPPQEALSCLQRLSTALKQLLEALQRLLSADSSVQDAQSLLSFIQTSEIAAMEPRFTAKSLFDCVSQQEYREKLCVGGAQLSELCVNLDQCAAAARSWP--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KUW4-1", "uniprot_id": "Q7KUW4_DROME", "id": "Q7KUW4-1", "name": "", "aln": "-------------------------------------------------------------------------MSLGGESKHTPKSSNLRPLDDDQLVRIISTPRPSNGVSQHPAQDRLKRLQGQLKRVQD-----NEKEQGTTKRITHSSSASRRSS-------ASTSTPQRLLKFPPKVAMNAWEKPK------------------ALVDAN----------------------------------------------------RLKAGRTQTAYQRLMLLRASLQQK---------QLYEERNNNIVAKINEEVIEKQPEACN--ITNPSAFDGSTAS----------DMEVEPMEWQESIEEEAAQN----------DQDEAKKGDDTLLMLPAESIEEEAPQKGQDEAKEEDDTILMLQAADAEELPPRLEDY-----------------------------------MYFVLDTNVLIHNHKFVERLTDVVLPGTVGSMLYLPYIVIKELDKLK-SKYQSDCLQR--VIAMRAIRFLNTKFDESFQIQAQSALEEADHLIKIDC-------PDDSILNCCLQLQAQVPH--MILLTNDANLRLKANASNIQVSCRSDLMSTYVDEFAGFGD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12104-1", "uniprot_id": "SWT1_YEAST", "id": "Q12104-1", "name": "Transcriptional protein SWT1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTDEKRAFPK-------------------------------------------------------------------------------GNNHIRSETFNGSVSHKISES------------IKDIASLRPHGKYTVQDIDNIIASTSSHENRGQSGDSNG---------------CINHDEEGDIP--------------MCDLNDESDVEMISEYLSSQREMEAQSVANYMPKINDDLPLLNPPTLKT--------------------------------------------AFVVDTNFIISHLNTLEKLRS--LSSTYHHLIIVPTTVIQELDGLKKSPDIARDNDDTTNQEHDRTIGTLARWGNDWIYKNLANLDSGLIGQKLKQSLNPGSLKDDSILDCCLYFKEILNC-FVILLSNDKNLCTKALTEDILTVSFRKNMDAKIIAMRAYEENQLRFANLRDSTVNNFDQNVTSYAHIPGIETPPLQFDK-----VSQNVFEQVKETIFFAIDHTLRKEYGEDIGFIDYNPDKLTTIENASNYIYLFWVSVFSELFTCSKIKKNEWKSLPTVLKSKPTNLNDLRTFEQFWETVLHFLFSKFTNE--------EKQSLEKQIHEWKTSINAIST--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . .. : . : : : : : . . . : . . . . . :. : ::: :*:***.:: : : :. : . . : :* *::*** :* : : .. ** :*.*** : ::* ::* ** *. ..: . . ", "identical_positions": 21, "similar_positions": 60, "identity": "2.09%" }, { "cls_id": "homologset.agr.RGD:1308696", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D211-1", "uniprot_id": "C2AIL_MOUSE", "id": "Q9D211-1", "name": "CDKN2AIP N-terminal-like protein", "aln": "MVGGEASAAVEKLVSGVRQAADFAEQFRSYSESEKQWKARMEFILRHLPDYRDPPDGGGRLDQLLSLSMVWANHLFLGCSYNKDLLDKVMEMADGIEVEDLPQFTTRSELMRKHQS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5RK03-1", "uniprot_id": "C2AIL_RAT", "id": "Q5RK03-1", "name": "CDKN2AIP N-terminal-like protein", "aln": "MVGGEATSAVEKLVSGVRQAADFAEQFRSYSESEKQWKARMEFILRHLPDYRDPPDGGGRLDQLLSLSMVWANHLFLGCSYNKDLLDKVMEMADGIEVEDLPQFTSRSELMKKHQS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96HQ2-1", "uniprot_id": "C2AIL_HUMAN", "id": "Q96HQ2-1", "name": "CDKN2AIP N-terminal-like protein", "aln": "MVGGEAAAAVEELVSGVRQAADFAEQFRSYSESEKQWKARMEFILRHLPDYRDPPDGSGRLDQLLSLSMVWANHLFLGCSYNKDLLDKVMEMADGIEVEDLPQFTTRSELMKKHQS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******::***:*********************************************.***********************************************:*****:****", "identical_positions": 110, "similar_positions": 6, "identity": "94.83%" }, { "cls_id": "homologset.agr.RGD:1308697", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q66H15-1", "uniprot_id": "RMD3_RAT", "id": "Q66H15-1", "name": "Regulator of microtubule dynamics protein 3", "aln": "MSRLGALGGSRAGLGLLLGTAAGLGFLCVLYSQRWKRTQRHGRSQSLPNSLDYAQTSERGRQVTQLRAIPGEAGDAAMLSSLPQEGQEKVLDRLDFVLTSLMALRREVEELQRSLQGLAGEIVGEVRSHMEENQRVARRRRFPFARERSDSTGSSSVYFTASSGATLTDAESEGGYTTA--NAESDY-ERDSDKESE-DAEDE---------VSCETVKMGRKDSLDLDMEVASSPASAALEDDDSSGLEDVQLLLQQADELHQGSEQNKQEGFQLLLNNKLAYGSRQDFLWRLARAYSDMTELTEEESEKKSYALNGKEEAEAALKKGDESAASHLWYAVLCGQLAEHEGISKRIQSGFSFKEHVDKAIELQPEDPRGHFLLGRWCYQVSHLSWLEKKTATALFESPLSATVQDALQSFLKAEELQPGFSKAGRVYISKCYRELGKNSEARKWLNLAQELPNITNEDSAFQKDLEELEVILGK-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UJU9-1", "uniprot_id": "RMD3_MOUSE", "id": "Q3UJU9-1", "name": "Regulator of microtubule dynamics protein 3", "aln": "MSRLGALGGSRAGLGLLLGTAAGLGFLCVLYSQRWKRTQRHGRSHSLPNSLDYAQASERGRQVTQFRAIPGEAGDAAILPSLSQEGQEKVLDRLDFVLTSLMALRREVEELQRSLQGLAGEIVGEVRSHIEENQRVARRRRFPFARERSDSTGSSSVYFTASSGAALTDAESEGGYTTA--NAESDY-ERDSDKESG-DAEDE---------VSCETVRMGRKDSLDLDVEAASSPAAAALEEDDSSGREDVQLVLLQADELHQGSKQDKREGFQLLLNNKLAYGSRQDFLWRLARAYSDMSDLTEEESGKKSYALNGKEEAEAALKKGDESAACHLWYAVLCGQLAEHEGISKRIQSGFSFKEHVDKAIELQPEDPRGHFLLGRWCYQVSHLNWLEKKTATALFESPLSATVQDALQSFLKAEELQPGFSKAGRVYISKCYRELGKNSEARKWMKLAQELPDVTNEDSAFQKDLEELEVILG------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96TC7-1", "uniprot_id": "RMD3_HUMAN", "id": "Q96TC7-1", "name": "Regulator of microtubule dynamics protein 3", "aln": "MSRLGALGGARAGLGLLLGTAAGLGFLCLLYSQRWKRTQRHGRSQSLPNSLDYTQTSDPGRHVMLLRAVPGGAGDASVLPSLPREGQEKVLDRLDFVLTSLVALRREVEELRSSLRGLAGEIVGEVRCHMEENQRVARRRRFPFVRERSDSTGSSSVYFTASSGATFTDAESEGGYTTA--NAESDN-ERDSDKESE-DGEDE---------VSCETVKMGRKDSLDLEEEAASG-ASSALEAGGSSGLEDVLPLLQQADELHRGDEQGKREGFQLLLNNKLVYGSRQDFLWRLARAYSDMCELTEEVSEKKSYALDGKEEAEAALEKGDESADCHLWYAVLCGQLAEHESIQRRIQSGFSFKEHVDKAIALQPENPMAHFLLGRWCYQVSHLSWLEKKTATALLESPLSATVEDALQSFLKAEELQPGFSKAGRVYISKCYRELGKNSEARWWMKLALELPDVTKEDLAIQKDLEELEVILRD-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5TYQ9-1", "uniprot_id": "Q5TYQ9_DANRE", "id": "Q5TYQ9-1", "name": "Regulator of microtubule dynamics protein 3", "aln": "MSWLGRN----ATIGLGVGVTISTGLIALLIIK--EAFRRRNRRLLLHN----------TRSALHNDAVDSSALTAAVQG-LSPDQQQELRKTLDEVMKSVSSLRNEIAELREGLKDITTTIAEDVKKTVEESQR-SRRRRSHMPRERTESMSSSSIYFTASAGIASAYDDSEVGYSTAYSNAESDYTDRETDRETDKDGEDEDRDSEEDEEQSCATVLTLRQEDSQAEEEEDED-SALMVESLTDIPIPELVLLLAQCDLLHAGDAEKKTEGFQLLMENRPLYADNAEFMWRLARAYSDMCETTENREEKKNYAEQGNYEAEAALTRNGLSADCHKWFAILARQSSQYDSIHGKLKSGHILKEHLDRALALCDDDPICFYLLGRWCLEVSSLSWLEKKAAATFYETSPTSSLNEALENFLKAEELNPGFSKTVRLYIAKCHKELGNLSEARNWVQLALNTPAGANEDSDVAALQTELKALIDSPTDQSTSSISN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** ** * :** :*.: . *::.:* : : :*:.* * * * . *: . * *:: *. : *::: . ** *:.*: :**.*: **: .*:.:: *. :*: :**.** :**** : ***::* .***:*****:* : : :** **:** ***** :*::*:*: *.*** ** ** *::. : : * .. :: :* . :: :* *.* ** *. : * ******::*: *... :*:********** : **: . **.** :*: ****** :.. ** .* *:*:*. * ::::.* :::**. :***:*:*: * ::* .:****** :** *.*****:*::: *:. ::::::**:.*******:*****: *:**:**::***: **** *::** : * ::** . **:.:: ", "identical_positions": 184, "similar_positions": 147, "identity": "37.17%" }, { "cls_id": "homologset.agr.RGD:1308698", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BGM7-1", "uniprot_id": "AAKG3_MOUSE", "id": "Q8BGM7-1", "name": "5'-AMP-activated protein kinase subunit gamma-3", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEP---------------------------------ELEHTLPG----------------TLTWSHSGGPESQEMDFLEQGENS---------------WPSPAVATSSERTCAIRGVKASRWTRQEAVEEAEPPGLGEGAQSRPAAESTRQEATFPK------------------------------------------------------------------------------ATPLAQAVPLAEAETS---PTGWDLLLP------------------------------------DCAASAGG---------------------------------------------------------------------------------------------------------------SSTGDLELTIEFPAPEAWDCELE-----------GLGKD------------RPRPGPSPQAPLLGLSWDDELQKPGAQVYMHFMQEHTCYDAMATSSKLVIFDTTLEIKKAFFAMVANGVRAAPLWDSKKQSFVGMLTITDFILVLHRYYRSPLVQIYEIEEHKIETWREIYLQGCFKPL--VSISPNDSLFEAVYALIKNRIHRLPVLDP----VSGTVLYILTHKRLLKFLHIFGALLPRPSFLCRTIQDLGIGTFRDLAVVLETAPVLTALDIFVDRRVSALPVVNESGQVVGLYSRFDVIHLAAQQTYNHLDMSVGEALRQRTLCLEGVLSCQPHESLGEVIDRIAREQVHRLVLVDETQHLLGVVSLSDILQALVLSPAG-------------------------IDALSA---------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A7E4-1", "uniprot_id": "D4A7E4_RAT", "id": "D4A7E4-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEP---------------------------------ELEHTLPGVPGSQGAAEKDSKRVATLTWSHSGGPESQEMDFLEPEENS---------------WPSPTVATSSERTCAIRGVKASRWTRQEAVEEAEPPGLGEGAQSGPAAESTRQKATFPK------------------------------------------------------------------------------ATPLAQAVPLADAETS---TTGWDLFLP------------------------------------DCAASAVG---------------------------------------------------------------------------------------------------------------SSTGDLELTIEFPGPEVWDCELK-----------GLEQD------------RPRPCPSPQAPLLSLSWDDELQKPGAQIYMHFMQEHTCYDAMATSSKLVIFDTTLEIKKAFFAMVANGVRAAPLWDSKKQSFVGMLTITDFILVLHRYYRSPLVQIYEIEEHKIETWREIYLQGCFKPL--VSISPNDSLFEAVYALIKNRIHRLPVLDP----VSGTVLYILTHKRLLKFLHIFGALLPRPSFLCRTIQDLGIGTFRDLAVVLETAPILTALDIFVDRRVSALPVVNESGQVVGLYSRFDVIHLAAQQTYNHLDMSVGEALRQRTLCLEGVLSCQPHESLGEVIDRIAREQVHRLVLVDETQHLLGVVSLSDILQALVLSPAG-------------------------IDALSA---------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UGI9-1", "uniprot_id": "AAKG3_HUMAN", "id": "Q9UGI9-1", "name": "5'-AMP-activated protein kinase subunit gamma-3", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEP---------------------------------GLEHALRR----------------TPSWSSLGGSEHQEMSFLEQENSSS--------------WPSPAVTSSSERIRGKRRAKALRWTRQKSVEEGEPPGQGEGPRSRPAAESTGLEATFPK------------------------------------------------------------------------------TTPLAQADP-AGVGTP---PTGWDCLPS------------------------------------DCTASAAG---------------------------------------------------------------------------------------------------------------SSTDDVELATEFPATEAWECELE-----------GLLEE------------RPALCLSPQAPFPKLGWDDELRKPGAQIYMRFMQEHTCYDAMATSSKLVIFDTMLEIKKAFFALVANGVRAAPLWDSKKQSFVGMLTITDFILVLHRYYRSPLVQIYEIEQHKIETWREIYLQGCFKPL--VSISPNDSLFEAVYTLIKNRIHRLPVLDP----VSGNVLHILTHKRLLKFLHIFGSLLPRPSFLYRTIQDLGIGTFRDLAVVLETAPILTALDIFVDRRVSALPVVNECGQVVGLYSRFDVIHLAAQQTYNHLDMSVGEALRQRTLCLEGVLSCQPHESLGEVIDRIAREQVHRLVLVDETQHLLGVVSLSDILQALVLSPAG-------------------------IDALGA---------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VDD2-1", "uniprot_id": "Q9VDD2_DROME", "id": "Q9VDD2-1", "name": "", "aln": "MATNCDFIEQPVKQQPLANAPVMGVQEDKAQEPKELPDEPAKQPDGQPYQHFAGEDSFECAFESTMDDLEQGVLDGYESDSEASANDQITDSASSGSLGQLAQQQQREERLRGLPGPLHGQHIDSEMLKCMPRSNSFDFHSSSGSSSDDEDDPDDDDDDQVHHSLGLSLSGKFVKVDLYSGHQRPGYLLPPYIERRRLSQCKEEDDEDEGDRTQLGGGSSSTGESTKSEKASKAPPRPPTPQDEASKEKFKDLERLRQQFMHKIDRINTRNIEESEAPPPPPPPPPPIPATILPKALKALLHTQEPVAPPSRPSPVGPPSPAPTSSVIVAKETPVPVTPEPVSPLPLPTEPPLIIKGKFKVTLAQETPELRVEAQKLSKLNASSNAHTISFPSSFGGYSSVQGLFSQRYGSNRFPTAAPHMSKQFFEPSLVEIRTPAQSNVALNTTGLANSNHQSLTCDTNSLANKPRTPSERELDEIWIRRQDGGLSGTAAPGAPGAPLPLLQQQQQQQRPVSLGGASTMPRLLRSESSASTTSPSRQLTNSGSVSVSVSDDEQDGSLGGAGRMPGSRPSSAPAEPNAKAAKKAYKKMEKEQRRQEKEQSRREKEARKLERETARRNEREAAKLEKINRHSEKISRSTERMAMAGVGSRSGSLERRRSGEDSPVLNQSTVHGIASPNRRPTIFDVFRPRAKSDAKRQKEKHLLDPSSADSSATSSTYSVSGGTGPATSSAAGGAGGAAAAAGQGAAGGAGGLMNSMKVAMQNFSHRQHPAVTITSADGTQSTAKSKYKDGSAHPHQGSDAQYYHTVTAVRPNSSQRSPMTKVMDLFRHRSSSVVSEADKRKARAAAHQQQLAVQSAHMRRASADLEKRRASVGAAGRGLRGDGTLDPHHAAILFRDSRGLPVADPFLEKVNLSDLEEDDSQIFVKFFRFHKCYDLIPTSAKLVVFDTQLLVKKAFYALVYNGVRAAPLWDSEKQQFVGMLTITDFIKILQMYYKSPNASMEQLEEHKLDTWRSVLHN-QVMPL--VSIGPDASLYDAIKILIHSRIHRLPVIDP----ATGNVLYILTHKRILRFLFLYINELPKPAYMQKSLRELKIGTYNNIETADETTSIITALKKFVERRVSALPLVDSDGRLVDIYAKFDVINLAAEKTYNDLDVSLRKANEHRNEWFEGVQKCNLDESLYTIMERIVRAEVHRLVVVDENRKVIGIISLSDILLYLVLRPSGEGVGGSESSLRASDPVLLRKVAEVEIPATAAAATTTTPPRSPSAGSGNRSLIEDIPEEETAPARSDDADSDNNKSASEDKANNNQHDQTTTAATANGDSNNSPVEVSFADEAQEEEAADQVERSNCDDDDQPALAEIERKNASMDDDEDDGMSSAVSAASALGQSLTPAAQEMALVSE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P12904-1", "uniprot_id": "AAKG_YEAST", "id": "P12904-1", "name": "5'-AMP-activated protein kinase subunit gamma", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKPTQDSQEKVSIEQQLAVES---IRKFLNSKTSYDVLPVSYRLIVLDTSLLVKKSLNVLLQNSIVSAPLWDSKTSRFAGLLTTTDFINVIQYYFSNP-DKFELVDKLQLDGLKDIERALGVDQLDTASIHPSRPLFEACLKMLESRSGRIPLIDQDEETHREIVVSVLTQYRILKFVALN---CRETHFLKIPIGDLNIITQDNMKSCQMTTPVIDVIQMLTQGRVSSVPIIDENGYLINVYEAYDVLGLIKGGIYNDLSLSVGEALMRRSDDFEGVYTCTKNDKLSTIMDNIRKARVHRFFVVDDVGRLVGVLTLSDILKYILLGSN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . .:* . :*:. :..** :..* :*:::** * :**:: .:: *.: :******:.. *.*:** **** ::: *: .* .: ::: ::: :.: . * .** *. .*::* ::..* *:*::* *: :**: *:*:*: : .. :: .: :* * * :: *:.:: .:. :.: ***::*:::. * ::.:* :**: * **.*.:*: :* :*. :*** .* .:.* :::.* : .***:.:**: :::*:::***** ::* . ", "identical_positions": 81, "similar_positions": 130, "identity": "5.76%" }, { "cls_id": "homologset.agr.RGD:1308699", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "G3X992-1", "uniprot_id": "MS3L2_MOUSE", "id": "G3X992-1", "name": "MSL complex subunit 3B", "aln": "----------------------------------MATLGCAPKDDGEGKDEGGSDRGDGDSKPKGKKEVEPHTRREADERAMRIPIPEVLQQRLADDCYYINR------RRRLVRLPCQTNVGAILECYVRHFSASVLALGDRRPQPQRAAP-----------ERSVGLCREMADGLRITFDHALPLVLLY---PQEQAQYEMVTSSTFFFPTEER----ASDAGRSQEAPWP-----GPSPPQPSESQAVAG-PAAPKRRRAEAEATRAPRRST---------------------RHSTHCHWQAEDRASPQAKR-------SVPKLFPHLQK-TPVHSAAPSPIALTPGKEGSA-------------------------MFAGFEG-TTEEINEILS-----WKLVPDN-----------YPPGHQPPPPSYIYGAQHLLRLFVKLPEILGKMSFSEKNLKALLKHLDLFLRFLAEYQADFFLESAYVSACEAHYSSKNPRTLC-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AYG1-1", "uniprot_id": "MS3L2_RAT", "id": "Q6AYG1-1", "name": "MSL complex subunit 3B", "aln": "----------------------------------MATLGCAPKDDGEGKDEGGSDRGDGDPKPKGKKEVEAHTRREADERAVRIPIPEVLQQRLADDCYYINR------RRRLVRLPCQTNVGAILECYVRHFSASALASGDRRPQPQRAAP-----------ERSVGLCREMADGLRITFDHALPLVLLY---PQEQAQYEMVTSSTFFFPTEER----ASDAGRSQEAPWP-----GPSPPQPSESQAMAG-PTAPKRRRVETDAARAPRRST---------------------RHSTHCHWQAEDRASPQAKR-------SVPKLFPHLQK-TPVHSTALSPIALTPGKEGSA-------------------------MFAGFEG-TTEEINEILS-----WKLVPDN-----------YPPGHQPPPPSYIYGAQHLLRLFVKLPEILGKMSFSEKNLKALLKHLDLFLRFLAEYQADFFLESAYVSACEAHYSSKNPRTIC-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0C860-1", "uniprot_id": "MS3L2_HUMAN", "id": "P0C860-1", "name": "MSL complex subunit 3B", "aln": "----------------------------------------------------------------------------MEERTVTLEIPEVLKRQLEDDCYYINR------RKRLVQLPCHTNIITILESYVKHFAISAAFSANERPRHHHAMPHASMNVPYIPAEKNIDLCKEMVDGLRITFDYTLPLVLLY---PYEQAQYKKVTASKVFLAIKES----ATNTNRSQEKLSPSLRLLNPSRPQSTESQSTSGEPATPKRRKAEPQAVQSLRRSS---------------------PHTANCDRLSKSSTSPQPKRWQQDMSTSVPKLFLHLEKKTPVHSRSSSP-TLTPSQEGSP-------------------------VFAGFEGRRTNEINEVLS-----WKLVPDN-----------YPPGDQPPPPSYIYGAQHLLRLFVKLPEILGKMSFTEKNLKALLKHFDLFVRFLAEYHDDFFPESAYVAASEVHYSTRNPQAVNKC-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P50536-1", "uniprot_id": "MSL3_DROME", "id": "P50536-1", "name": "Protein male-specific lethal-3", "aln": "MTELRDETPLFHKGEIVLCYEPDKSKARVLYTSKVLNVFERRNEHGLRFYEYKIHFQGWRPSYDRCVRATVLLKDTEENRQLQRELAEAAKLQIRGDYSYKGTPDKPSAKKKRGGKAAHVEEPIVVPMDTGHLEAEHEMAPTPRAAGNRTRDNSGGKRKEKPPSGDGRLKGNRGRQTETFYNNAINDVSVYNHVPQEDRIMMRVSERLRELIEYDRNMIKVLGKQHALPARVPIVTIMENFVKQQAVELAISIKQDSSRARNTQSRNARMEREYDRVMSTVCMLKEVVDGLRIYFEFHVDDHLLYTEEKEYVHNYLTDDNMRNCSLILNKSYEYINPSGDTELIGLDGTPVVEGSGDTNGQIGVINIGGPEYEKQLQKCLLYIVTASGKNTAQAYERTSPYTAAYKLPVEMRGFLNETFKWRLLSAESPPEKSMVFGAPHLVRLMIKMPMFLNASPISNKKLEDLLPHLDAFINYLEN-HREWFDRENFVNSTALPQEDLQRELLDSLDGIAA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::* : :.*. : :: .* * . ::: ..:.: :: . *: . *. ::: . . * : . :: :: * :* * *: *: : : . . :: * * : . : : :.: *..:. .: *. * . ::. : . * : .* . ** *** :. .* * : * * :** : ....** * ::** **:**::*:* :*. .:::*:*: ** *:* *:.:* : : ::* .. :* : . : . : ", "identical_positions": 52, "similar_positions": 108, "identity": "10.14%" }, { "cls_id": "homologset.agr.RGD:1308701", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZNS8-1", "uniprot_id": "D3ZNS8_RAT", "id": "D3ZNS8-1", "name": "Aladin", "aln": "-MCSLGLFPPPPPRGQ-VTLYEHNNELVTGNSYESPPPDFRGQWINLPVLHLTKDPLKAPGRLDHGTRAAFIHHREQVWKRCINVWHDVGLFGVLNEIANSEE-EVFEWVKTASSWALALCGRASSLHGSLFPHLSLRSEDLIAEFAQVTNWSSCCLRVFAWHPHTNKFAVALLDDSIRVYNANS--TIVPSLKHRLQRNVAALAWKPLSAS-VLAVACQSCILIWTLDPTSLSTRPSSGCA-----QVLSHPGHTPVTSLAWAPNGGWLLSASPVDAVILVWDVSTETCVPLPWFRG--GGVTNLLWSPDGSKVLATTPSAVFRVWEA--RMWTCEGWPTLSG-RCQTGCWSPDGKRLLFTVLGEALIYSLSFPEPCGTEKGHVGGAKSATIVADLSETTIQTPDGEERLGGEAHAMVWDPSGERLAVLMKGNPRVQDGNPVILLFRTRNSPVFELLPCGVIQGEPGAQAQLVSFHPAFNKG--ALLSVCWSTGRITHIPLYFVNAQFPRFSPVLGRAQEPPAGGGGSVHEVPLFTETSPTSAPWDPLPGLPSAQPHSPHSHL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P58742-1", "uniprot_id": "AAAS_MOUSE", "id": "P58742-1", "name": "Aladin", "aln": "-MCSLGLFPPPPPRGQ-VTLYEHNNELVTGNSYESPPPDFRGQWINLPVLHLTKDPLKAPGRLDHGTRTAFIHHREQVWKRCINVWHDVGLFGVLNEIANSEE-EVFEWVKTACSWALALCGRASSLHGSLFPHLSLRSEDLIAEFAQVTNWSSCCLRVFAWHPHTNKFAVALLDDSIRVYNANS--TIVPSLKHRLQRNVAALAWKPLSAS-VLAVACQSCILIWTLDPTSLSTRPSSGCA-----QVLSHPGHTPVTSLAWAPNGGWLLSASPVDAVILVWDVSTETCVPLPWFRG--GGVTNLLWSPDGSKVLATTPSAVFRVWEA--QMWTCEAWPTLSG-RCQTGCWSPDGNRLLFTVLGEALIYSLSFPERCGTGKGHVGGAKSATIVADLSETTIQTPDGEERLGGEAHSMVWDPSGERLAVLMKGNPQVQDGNPVILLFRTRNSPVFELLPCGIIQGEPGAQAQLITFHPSFNKG--ALLSVCWSTGRITHIPLYFVNAQFPRFSPVLGRAQEPPAGGGGSIHEVPLFTETSPTSAPWDPLPGQSSAQPHSPHSHL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NRG9-1", "uniprot_id": "AAAS_HUMAN", "id": "Q9NRG9-1", "name": "Aladin", "aln": "-MCSLGLFPPPPPRGQ-VTLYEHNNELVTGSSYESPPPDFRGQWINLPVLQLTKDPLKTPGRLDHGTRTAFIHHREQVWKRCINIWRDVGLFGVLNEIANSEE-EVFEWVKTASGWALALCRWASSLHGSLFPHLSLRSEDLIAEFAQVTNWSSCCLRVFAWHPHTNKFAVALLDDSVRVYNASS--TIVPSLKHRLQRNVASLAWKPLSAS-VLAVACQSCILIWTLDPTSLSTRPSSGCA-----QVLSHPGHTPVTSLAWAPSGGRLLSASPVDAAIRVWDVSTETCVPLPWFRG--GGVTNLLWSPDGSKILATTPSAVFRVWEA--QMWTCERWPTLSG-RCQTGCWSPDGSRLLFTVLGEPLIYSLSFPERCGEGKGCVGGAKSATIVADLSETTIQTPDGEERLGGEAHSMVWDPSGERLAVLMKGKPRVQDGKPVILLFRTRNSPVFELLPCGIIQGEPGAQPQLITFHPSFNKG--ALLSVGWSTGRIAHIPLYFVNAQFPRFSPVLGRAQEPPAGGGGSIHDLPLFTETSPTSAPWDPLPGPPPVLPHSPHSHL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32U053-1", "uniprot_id": "A0AB32U053_DANRE", "id": "A0AB32U053-1", "name": "", "aln": "MMCSLAVFPPPLAAGHTHTLMEQHNELQASDPQ-----------VDLPSPQFTRDTLKGHSRAESSSKSAFLDQRDTLWRRSAGAWRDAGLYGLLDQITNSAD-EVPRCVSVGSSCLLALLRWSSSFHGSLFPHLTLSSDEMVAEFSQMLDWSDSAVRSFSWHPHTDKFAVALLDDSIKIYKPHS--STAPTLKHRCQRSVCALQWKPLCGS-ALAVACQSCLLIWHVDPASLSTRPSSGCA-----QVLSHPGHSPITSIAWSPTGSLLVSASPVDTAMMVWDVAAESCVPLRRVGG--GGVTFLSWSPDGSRLLAATPSALFRVWET--RMWTCERWPCLKG-SCQSACWSPDGACLLLSIQGERLIYALSFSDLTG-------GPKAATVVADLSETSFPGPEGDLTVGGEVCSLSWDPRGERLAVLLKGDAQSTDHPSVIAVFKTRCSPAFELLPCGFVMGEAGAEPRFMQFHPHFQHG--ALLTVCWSDGRITHVPFYFS-------SAGLSDSQRPAALSTADRSISRLYTEDLH-----------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W351-1", "uniprot_id": "AAAS_DROME", "id": "Q9W351-1", "name": "Aladin", "aln": "-MAALSNLKQCPPFSTLPDLALRHNHIPELERY--------------PQINLNSELLANPAGQRYYGGQSFVSVNEGVLKRIARSFFNGGFWKTLEEARSPETREQAPLIAQAGDLIAQFLGLATGLR--ILPHTQQLSAERIAQFVETRDWLNSDVRYLAWNQHFFCLAVAGVDDVVRIYTKSSSATTATVLKSPSQTQITCMAWRPLCAS-EIVIGCRQGLCFWEVDSTLHLGR-TNAPS-----EIFKYPNNLPITSMQWNKDGTQLATASIGDRSIIIWQPDTGMMQPLKRLGP--PGS-LLKWSPDNDWLFAATVDRVFRVWNCH-QQWTTERWVCGPGGYVQTACWSPCGRFLLFVSSAEPILYRLQFVQQSLLSSS--ADEKEILPIADLNACSIDAN--RTLVGGPAQQLAWDPHGNYLVVTFKATNCIAVFRTFIQKFDLQISAAYYLS-----GETAAEHPSFICFQPLYEDNDRSVLTIAWSSGRIQYYAFD-------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VL33-1", "uniprot_id": "Q9VL33_DROME", "id": "Q9VL33-1", "name": "Aladin", "aln": "-------------------------------------------------MQRSNEEFRETNAPICNNQQ----------QRCVDFVRNN------ANIGNRTEEVLNLLWELANEYWQWFLQKLGQLKRLCFRPECRIDPEILERISQTRGWKTSVIRFIECHPSSSLMAFLTNDDVVLICDKNY--DCPTKIQSVRQKDTTCVAFRPWSQTCEFAVGCAAGICLWSDSRRLNANRNIRRMMGTHHLQVLQDKGHNYVTSMQWNEDGTILVTAAFGSSHIMLWEPDCQQKIRLIPNPKSLGSFSLLRFSPDFHVLFCASCDAGASLCQLNRSKWKLKQILGQQR--IQSAVWTTCGSTLLYACYGSTRVYSCTSDGEDSVFLR-PQSIWRVQLIMDLQLVTTCAG--QRLCCGEPQCLAMDPLGIYMASIFKEQSFVLLCILHTSRWGNVKLLPVEFIYC---DMDGDQYPAYISFGVLKAEIR--FLIIAWNTGHFQRYDITAQCFRDAQLYHNIN-----------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : : :* : : . . : :: : . : : .: : .* . :* : : :*. ** : : . :: * . .: ::* . : :.:.* : :* . * :::. .: :**: * * * :*: . : :*: * . * :*** ::.:: . : : *. : *:. *:. * ** .. :* . : **. : * : ** * :. :* : : . : * . .* : *. *:: : ", "identical_positions": 41, "similar_positions": 97, "identity": "7.27%" }, { "cls_id": "homologset.agr.RGD:1308702", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K2Z2-1", "uniprot_id": "PRP39_MOUSE", "id": "Q8K2Z2-1", "name": "Pre-mRNA-processing factor 39", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQNSHMEEYRNS--DNGSTG-----------------------------NSSEVAVVEHPDFSTEIMNVTEME---------------------------QSPDASPSAHASTEEN-----------------------------------EMANAVNLPVT---EAEGD--------FPPEFEKFWKTVEMNPQDFTGWVYLLQYVEQENHLMAARKAFDKFFVHYPYCYGYWKKYADLEKRHDNIKQSDEVYRRGLQAIP-LSVDLWIHYINFLKETLEPGDQETNTTIRGTFEHAVLAAGTDFRSDKLWEMYINWENEQGN-LREVTAVYDRILGIPTQLYSHHFQRFKEHVQNNLPRDLLTGEQFIQLRRELAS---------VNGHSGDD-------------------------------------GPPGDDLPSGIEDIS-PAKLITEIEN--------------------------MRHRIIEIHQEMFNYNEHEVSKRWTFEEGIKRP--YFHVKPLEKAQPKKNWKEYLEFEIENGTHERVVVLFERCVISCALYEEFWIKYAKYMENHS-----IEGVRHVFSRACTVHLPKKPMAHMLWAAFEEQQGNINEARIILRTFEECVLGLAMVRLRRVSLERRHGNMEEAEHLLQDAIKNAKSNNESSFYAIKLARHLFKIQKNLPKSRKVLLEAIEKDKENTKLYLNLLEMEYSCDLKQNEENILNCFDKAIH-GSLPI-------KMRITFSQRKVEFLEDFGSDVNKLLNAYDEHQTLLKEQDTLKRKAENGS--EEPEEKKAHTEDLSS--AQIIDGDLQANQAAYNYSAWYQYN---------------------YQNPWN----------------YGQYYPPPPT-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A5S9-1", "uniprot_id": "D4A5S9_RAT", "id": "D4A5S9-1", "name": "Pre-mRNA-processing factor 39", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQNSHMDEYRNS--DNGSTG-----------------------------NSSEV-VIEHPDFSTEIMNVTEME---------------------------QSPDASPSVRVSTEEN-----------------------------------EMANAVDLPVT---ETEGN--------FPPEFEKFWKTVETNPQDFTGWVYLLQYVEQENHLMAARKAFDKFFIHYPYCYGYWKKYADLEKRHDNIKQSDEVYRRGLQAIP-LSVDLWIHYINFLKETLDPGDPETNSTIRGTFEHAVLAAGTDFRSDKLWEMYINWENEQGN-LREVTAVYDRILGIPTQLYSHHFQRFKEHVQNNLPRDLLTGEQFIQLRRELAS---------VNGHNGDD-------------------------------------GPPGDDLPSGIEDITDPAKLITEIEN--------------------------MRHRIIEIHQEMFNYNEHEVSKRWTFEEGIKRP--YFHVKPLEKAQLK-NWKEYLEFEIENGTHERVVVLFERCVISCALYEEFWIKYAKYMENHS-----IEGVRHVFSRACTVHLPKKPMAHMLWAAFEEQQGNINEARIILRTFEECVLGLAMVRLRRVSLERRHGNMEEAEHLLQDAIRNAKSNNESSFYAIKLARHLFKIQKNLPKSRKVLLEAIEKDKENTKLYLNLLEMEYSCDLKQNEENILNCFDKAIH-GSLPI-------KMRITFSQRKVEFLEDFGSDVNKLLNAYDEHQTLLKEQDTLKRKAENGS--EEPEEKKAHTEDVSS--AQIIDGDLQANQAAYNYSAWYQYN---------------------YQNPWN----------------YGQYYPPPPT-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q86UA1-1", "uniprot_id": "PRP39_HUMAN", "id": "Q86UA1-1", "name": "Pre-mRNA-processing factor 39", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQNSHMDEYRNS--SNGSTG-----------------------------NSSEVVVEHPTDFSTEIMNVTEME---------------------------QSPDDSPNVNASTEET-----------------------------------EMASAVDLPVTLT-ETEAN--------FPPEYEKFWKTVENNPQDFTGWVYLLQYVEQENHLMAARKAFDRFFIHYPYCYGYWKKYADLEKRHDNIKPSDEVYRRGLQAIP-LSVDLWIHYINFLKETLDPGDPETNNTIRGTFEHAVLAAGTDFRSDRLWEMYINWENEQGN-LREVTAIYDRILGIPTQLYSHHFQRFKEHVQNNLPRDLLTGEQFIQLRRELAS---------VNGHSGDD-------------------------------------GPPGDDLPSGIEDITDPAKLITEIEN--------------------------MRHRIIEIHQEMFNYNEHEVSKRWTFEEGIKRP--YFHVKPLEKAQLK-NWKEYLEFEIENGTHERVVVLFERCVISCALYEEFWIKYAKYMENHS-----IEGVRHVFSRACTIHLPKKPMVHMLWAAFEEQQGNINEARNILKTFEECVLGLAMVRLRRVSLERRHGNLEEAEHLLQDAIKNAKSNNESSFYAVKLARHLFKIQKNLPKSRKVLLEAIERDKENTKLYLNLLEMEYSGDLKQNEENILNCFDKAVH-GSLPI-------KMRITFSQRKVEFLEDFGSDVNKLLNAYDEHQTLLKEQDSLKRKAENGS--EEPEEKKAHTEDTTSSSTQMIDGDLQANQAVYNYSAWYQYN---------------------YQNPWN----------------YGQYYPPPPT-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1JPZ7-1", "uniprot_id": "PRP39_DANRE", "id": "Q1JPZ7-1", "name": "Pre-mRNA-processing factor 39", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEDSGESMTGMLDSKSPESGDSPAMEGTTGTDDVT----------------------GLSTSDLTTEQPPESQEQTQPVSDMEFSVEHL-----------------KTAVQNIDQSASPAEPAAENSEQPPESNGQQEDQSEQPDDVKEAGQGDSESPSNMELEDAPKEPAEP--AAEADPAAPQEPELPTEYERLSKVVEDNPEDFNGWVYLLQYVEQENHLLGSRKAFDAFFLHYPYCYGYWKKYADIERKHGYIQMADEVYRRGLQAIP-LSVDLWLHYITFLRENQDTSDGEAESRIRASYEHAVLACGTDFRSDRLWEAYIAWETEQGK-LANVTAIYDRLLCIPTQLYSQHFQKFKDHVQSNNPKHFLSEEEFVSLRVELAN---------ANKPSGDEDAET---------------------------------EAPGEELPPGTEDLPDPAKRVTEIEN--------------------------MRHKVIETRQEMFNHNEHEVSKRWAFEEGIKRP--YFHVKALEKTQLN-NWREYLDFELENGTPERVVVLFERCLIACALYEEFWIKYAKYLESYS-----TEAVRHIYKKACTVHLPKKPNVHLLWAAFEEQQGSIDEARSILKAVEVSVPGLAMVRLRRVSLERRHGNMEEAEALLQDAITNGRNSSESSFYSVKLARQLVKVQKSIGRAKKVLLEAVEKDETNPKLYLNLLELEYSGDVQQNEAEIIACFDRALS-SSMAL-------ESRITFSQRKVDFLEDFGSDINTLMAAYEQHQRLLAEQESFKRKAENGS--EEPDAKRQRTDDQSVASGQMMD--MQANHAGYNYNNWYQYNSW------------------GSQNSWGQY---------GQYGQYNQYYPPPPT-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KRW8-1", "uniprot_id": "PRP39_DROME", "id": "Q7KRW8-1", "name": "Pre-mRNA-processing factor 39", "aln": "MASEGENVVMESPGRRTRSGRKAASPAASLPTRSTRRTSKRNVQLSDHEEEAEEQVVMVQEEEEPFRGTNTAEAPALEPQFEETQHQIEDDVEMLPAEAAGVDEKSSSFPFGTVAELHSETSDDIKETRGQAGVDTLLASLAGDNANSLPSVGGNDESDNVKKADFEYNVDSLQPQMEKMNSSEDSSSQHAIAEDLADADTSNATIVNTEIVSEDELPLPSKPEINDAEEVSDEELPAPQRAELPEDAEVISEDELPASNNNNTATEPKAPLKRKAENESVKSTEDKDASSHESSTKDKSSEQYNPGSPTSESNDAQPSEKKLKVEESEPKEKKKEKERDKDKEKDKDKDNNKDKEKERKKLPDLDKYWRAVKEDSTDFTGWTYLLQYVDNESDAEAAREAYDTFLSHYPYCYGYWRKYADYEKRKGIKANCYKVFERGLEAIP-LSVDLWIHYLMHVKSN----HGDDETFVRSQYERAVKACGLEFRSDKLWDAYIRWENESKR-YHRVVQIYDRLLAIPTQGYNGHFDNFQDLINQHDVTITLANEEVIRLRKDFHERQQSKSSKSSSKHRRDSSSSSKDKDSKEREREKDKDKDKDKDKEKRETVGGGVGKSPKDTSETQVDESDSTTDLTTESESSHAASKPAMQIDFSDLSTLNDEEVVSIRDRAISARRKVHKLTVSAVTARWSFEEGIKRP--YFHVKPLERAQLK-NWKDYLDFEIEKGDRERVLVLFERCLIACALYDEFWLKMLRYLESLEDQSGVVDLVRDVYRRACRIHHPDKPSLHLMWAAFEECQMNFDDAAEILQRIDQRCPNLLQLSYRRINVERRRGALDKCRELYKHYIESTKNKGIAGSLAIKYARFLNKICHDLDAGLAALQQALERDPANTRVALQMIDLCLQ-RPKVDEQEVVEIMDKFMARADIEP-------DQKVLFAQRKVEFLEDFGSTARGLQDAQRALQQALTKAKEAQKKSDGSPSRKNSSSSKEGPVPTGSAAAAYNNGGSAAAVAGYNYGAANPYYGQQNTAAAYPSQTPQQASYDSYYNQWGYGSGGASANSGGSGYNYGQWSGYGNYY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03776-1", "uniprot_id": "PRP42_YEAST", "id": "Q03776-1", "name": "U1 small nuclear ribonucleoprotein component PRP42", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDKYTALIHDENFSTLTLNVSRYP--------------------------------------------------------------------------------------------------------KSLAYWEKLLNYIVKAS-------APICKSTEPQLLKLIRCTYSSMLNEFPYLENYYIDFALLEYKLGNVSMSHKIFQRGLQAFNQRSLLLWTSYLKFCNNVIS-----HQKQLFKKYETAEEYVGLHFFSGEFWDLYLEQISSRCTSSKKYWNVLRKILEIPLHSFSKFYALWLQRIDD-----IMDLKQLSQLTS------------------------------------------------------------KDELLKKLKIDINYSGRKGPYLQD--------------------------AKKKLKKITKEMYMVVQYQVLEIYSIFESKIYINYYTSPETLVSSDEIETWIKYLDYTITLQTDSLTHLNFQRALLPLAHYDLVWIKYSKWLINSKND---LLGAKNVLLMGLKFSLKKTEIIKLLYSVICKLN----------------------------EYVLLRNLLEKIESSYSDNVENVDD------FEIFWDYLQFKTFCQNSLYSSRYSDSQSNGLLNKELFDKVWKRLSCKEKKSGQEILLNNLVQFYSKDTVEF-------VEKNIF-QKIIEFGWEYYLQNGMFWNCYCRLIYFDTSRSYLDKRQYIVR-KIWPQIDKKFAQSVLPSLTEFCESYFPEEMDTLEEMFTEEP-------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P39682-1", "uniprot_id": "PRP39_YEAST", "id": "P39682-1", "name": "Pre-mRNA-processing factor 39", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPDETNFTIEDIEPR------------------------------PDALRGLDTQFLQDNTALVQAYR------------------------------------------------------------------------------------------------------------GLDWSDISSLTQMVDVIEQTVVKYGNPNDSIKLALETILWQILRKYPLLFGFWKRFATIEYQLFGLKKSIAVLATSVKWFP-TSLELWCDYLNVLCVN----NPNETDFIRNNFEIAKDLIGKQFLSHPFWDKFIEFEVGQKN-WHNVQRIYEYIIEVPLHQYARFFTSYKKFLNEKNLKTTRNIDIVLRKTQTTVN-----------------------------------------------------------------EIWQFESKIKQPFFN--------------------------LGQVLNDDLENWSRYLKFVTDPSKSLDKEFVMS--VFDRCLIPCLYHENTWMMYIKWLTKKNISDEVVVDIYQKANTFLPLDFKTLRYDFLRFLKRKYRSNNTLFNNIFNETVSRYLKIWPNDILLMTEYLCMLKRHSFKNSLDQSPKEILEKQTSFTKILETSITNYINNQIDAKVHLQTLINDKNLSIVVVELIKTTWLVLKNNMQTRKYFNLYQKNILIKN-SVPFWLTYYKFEKSNVNFTKLNKFIRELGVEIYLPTTVMNDILTDYKTFYLTHSNIVTYESSIIDSNTFDPILYPELKMSNPKYDPVLNTTANVDWHKKTEWKEAGHIGITTERPQISNSIIECNSGTLIQKPISLPNFRN----------------LEKINQVKIN------------DLYTEEFLKEGK-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : : : . . :: .:* .:: :* * : . : .:: : *: ** *: : :* * * .* * :*: :: . : :: :* : : .: : . ::. . . . . . .: . :: : : .* *:.: . . : : : . : :: ..: :: : : . : . . : * . . . . . .: : .. : : . . . . .. .. : ", "identical_positions": 17, "similar_positions": 103, "identity": "1.57%" }, { "cls_id": "homologset.agr.RGD:1308703", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZYK4-1", "uniprot_id": "A0A8I5ZYK4_RAT", "id": "A0A8I5ZYK4-1", "name": "Intraflagellar transport protein 27 homolog", "aln": "MTKGVRVCAHARTCVRTFLSLAAQRSPGRSRWSTSLENEISHGERSLLTSLLPAQRREQAAAQPGDPAVGKTALVQMFRSDGTHFQKNYTLTTGVDLVVKTVPVLDTNDSVELFIFDSAGKELFSEMLDKLWENPNVLCLVYDVTNEQSFISCTKWLEKVRSQTPGISLPGVLVGTKTDLAGRQTVDSAQAQAWALSQGLEFFETSVKEMDNYEAPFHCLAKQFYQLYREKVDIFHTLV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D0P8-1", "uniprot_id": "IFT27_MOUSE", "id": "Q9D0P8-1", "name": "Intraflagellar transport protein 27 homolog", "aln": "-----------------MVKLAAK------------------------------------CILAGDPAVGKTALVQMFRSDGTHFQKNYTLTTGVDLVVKTVPVLDTNDSVELFIFDSAGKELFSEMLDKLWENPNVLCLVYDVTNEQSFISCTKWLEKVRSQTSGISLPGVLVGTKTDLAGRQTVDSAQAQVWALSQGLEFFETSVKEMDNYEAPFHCLAKQFYQLYREKVDIFHTLV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BW83-1", "uniprot_id": "IFT27_HUMAN", "id": "Q9BW83-1", "name": "Intraflagellar transport protein 27 homolog", "aln": "-----------------MVKLAAK------------------------------------CILAGDPAVGKTALAQIFRSDGAHFQKSYTLTTGMDLVVKTVPVPDTGDSVELFIFDSAGKELFSEMLDKLWESPNVLCLVYDVTNEESFNNCSKWLEKARSQAPGISLPGVLVGNKTDLAGRRAVDSAEARAWALGQGLECFETSVKEMENFEAPFHCLAKQFHQLYREKVEVFRALA", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::.***: . .**********.*:*****:****.******:********* **.*************************.*************:** .*:*****.***:.**********.*******::****:*:.***.**** ********:*:***********:*******::*::*.", "identical_positions": 147, "similar_positions": 34, "identity": "61.51%" }, { "cls_id": "homologset.agr.RGD:1308704", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AHL9-1", "uniprot_id": "A0A8I6AHL9_RAT", "id": "A0A8I6AHL9-1", "name": "Collagen alpha-3(VI) chain", "aln": "MRKHRHLPLVAVFSLLLSGITMTHAQ-QQSDVKNGAAADILFLVDSSWSAGKDRFLLVQEFLSDVVESLSVGDNDFHFALVRLNGNPHTEFLLNAYHSKQEVLSHILNMSYIGESNQTGKGLEYIIHSHLTEASGSRAADGVPQVIVVLTDGQSEEDGFALPSAELKSADVNVFAVGVEDADERTLREIASEPLSMHVFNLENVTSLHDMVGNLVSCIHSSVNPERAGDKESLKDITAQDSADIIFLIDGSQNTGKANFDVIRDFLVNVLERLSVGNQQVRVGVVQYSDEPRTMFSLDSYPSKAAVLDAVKRLSFAGGELANIGQALDFVVENHFTRTGGSRVEEGVPQVLVLISAGPSSDEIRDAVVALKQGSVFSFGLGAQAASRVELQHIATDDNLVFTVPEFRSFGDLQEQLLPYLVGVAQRHFVLQPPAIVTQVMEVNKRDIVFLVDGSSSLGQANFNAIRDFISRVIQRLEIGQDLVQVSVAQYADTVKPEFYLNTYSTKKDAITTVRKMKALEGSALYTGSALDFVRNNLFTSSAGHRAAEGVPKLLVLITGGKSLDDVSQAAQELQKGSIMALVIGSRAADEDELKEIAFDSSLVFIPAEFRPAPLQSMLPSLMAPLRTLTGTTEVHVNKRDIIFLLDGSDNVGKNNFPYVRDFVTNLVNSLDVGSDNIRVGLVQFSDTPVTEFSLDTYQTKSELLAHLRRLQLKGGTGLNAGSALSYVHANHFTEAGGSRIREHVPQLLLLLMAGPSEDVYLQAANALVRSGVLTFCVGTNQADKAELERIAFNPSLVYLMDDFSALPALPQQLIQPLTTYVSGGVQEVPLSQPEVKRDILFLFDGSVNVMGQFPAVRDFLYRIIEELDVKPDGTRVAIAQFSDDVRVESRFNEHQTKAEILNLVKKMKLKTGKGLNLGLALDHALRTIFVRSAGSRIEDNVQQFLVLLVAGRSTDAVAGPASSLKQRGVIPFIFQAKNANPSELEQIVPSPAFILAAESLPKIGDLQSEIVGLLKAKQ--TSDTVSGEKDVVFLIDGSEGVRSGFPLLKEFVQRVVESLDVGPNQVRVALVQYSDRTRPEFYLNSHMDQQGVISAIRRLTLLGGPTPNTGAALDFVLRNILTSSTGSRIEEGVPQLLIVLTAERSGDDVRGPSVVLKQGGAVPIGIGIGNADISEMQTISFIPDFAVAIPTFRELGTIQQVISERVIQLNREQLSSLTPVLMPSPSAGPGNKKDVVFLIDGSQNAGAEFQHIRTLIERLVEYLDIGFDTTRVAVIQFSEDTKMEFPLNAHFSKDEVQNAVRRLRPKGGRQVYIGNALEYVLKNIFQRPLGSRIEEGVPQFLVLISSGKSADEVDDSAVELKQFGVAPLTVARHTDQEELVKISLSPEYVFSVSTFRELPRLEQRLLTPITTLTSQQIQQILASTRYPPSVAESDAADIVFLIDSSDAMKPDGIAHIRDFVSRIVRRLNIGPNKVRIGVVQFSNDVFPEFYLKTHKSQNSVLEAIRRLRFKGGSPLNTGRALEFVARNLFVKSAGSRIEDGVPQHLVLFLGGKSQDDVSRHAQVISSSGIMSLGIGDRNIDRTDLQTITNDPRLVFTVREFRELPNIEERVMLSFGPSGPTPQPPEVEFPS-SRPEKKKADIVFLLDGSINFRRDSFQEVLRFASEIVDTVYEDGDSIRVGLVQYNSDPTDEFFLRDFSTKRQIIDAINKVIYKGGRHANTRVGIEHLLKNHFVSEAGSRLDERVPQIAFVITGGKSVEDAQDVSLALTQKGVKVFAVGVRNIDSEEVGKIASNSATAFRVGSVQELSELSETVLETLHDAMHETLCPGVTDVSKACNLEVILGFDGSRDQNVFVSQKGLESKVDTILNRISQIQRISCSSNQLPTVRVSVVANTPSGPVEAFDFAEYQPDLFEKFRTMRSQHPYVLTADTLKLYQNKFRQSSPDTVKVVIHFTDGADGDMADLYRASEELRQAGVQALILVGLERVANLERLMQVEFGRGFMYDRPLRLNLLDLDYELAEQLDNIAEKACCGVPCKCSGERGDRGPIGSIGPKGISGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFPGEKGELGEIGLDGLDGEEGDKGLPGSSGEKGSPGRRGDKGPKGDKGERGDVGIRGDPGDSGRDSQQRGPKGETGDIGPMGLPGRDGIPGSPGDPGKDGGFGRRGPAGAKGNRGGPGQPGFEGEQGTRGSQGPPGPIGPPGLIGEQGIPGPRGGGGTAGAPGERGRTGPLGRKGEPGEPGPKGGTGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGTPGEPGADGPPGPKGIRGRRGNSGPPGVVGQKGDPGYPGPSGHRGNRGDSVDQCALIQSIRDKCPCCYGPLECPVFPTELAFALDTSEGVTQDTFSRMREVLLSIVGDLTIAESNCPRGARVAVVTYNNEVTTEIRFADSKKKSALLDSIQNLQVALTSKQPSLETAMSFVARNTFKRVRNGFLMRKVAIFFSNQPTKPSLQLREAVLKLSDAGITPLFLTSQEDRELINALQINNTAVGHALVLPARRDLRDFLKNVLTCHVCLDICNIDPSCGFGNWRPSFRDRRAAGSDVDIDLAFILDSSEATTLFQFNEMKKYISYMVRQLDLSPDPKASQHFARVAVVQQATYESVDNTSVPPVKVEFSLTDYGAKEKLLDFLSRRMTQLQGTMDLGNAIEYTIENIFESAPNPRDLKIVVLMLTGEIPREQLEEAQRAILQAKCKGYFFVVLGIGRKVNVKEVYSFASEPNDVFFKFMDKSTELNEEPLMRFGRLLPSFVGSGNAFYLPPDLRKQCDWFQGDQPVKNGVKFGHRQINTPHTVNSSLTSKVVTTMKPVTTTKPTSIVNLPPAKPAPVRPAPAQPVLAKPDPAKPVSAKSVPPQPVHAQPDPAQPVHVQSASAQTASAKPAPAKPAPPQTAAAKPAPPQTAAAKPAPPQTAAAKPAPPQTAAAKPVPVKPAPAQPVHVQSASAQTASAKPVPAKPAPPQTAAAKPVPVKPAVPAQPAPAQPVHAQPAPAQPVLTKPAAMKPASANKPVAAKPVATN--TATVRPASAVKPAAASKPAATRPLPAAVRPVATKPEAPR-PQAKPAATKPATTKPMARVSREVQVSEVTENSARLHWERPEPSSSYFYDLTVTSAHDQSLVLRQNLTVTDRVIGGLLAGQLYHVVVVSYLQSQVRAIYQGSFNTKKTQPPVLQAAHRASSSTINLMVNTEPLFLTKTDICKLPKDAGTCEDFKLLWHYDLESKSCKRFWYGGCGGNENRFHSQEECEKMCSPELSV---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A087WS16-1", "uniprot_id": "A0A087WS16_MOUSE", "id": "A0A087WS16-1", "name": "", "aln": "MRKHRHLPLVAVFSLLLSGIATTHAQ-QHG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VMEVNKRDIVFLVDGSSSLGPSNFNAIRDFVTRVIQRLEIGQDLVQVSVAQYADTVKPEFYLNSYTNKRDAITAVRKMRALNGSALYTGSSLDFVRNNLFTSSAGHRAAEGVPKLLVLITGGKSLDEVSQPAQELKRGSIMALAVGSKAADEDELKEIAFDSSLVFIPAEFRPAPLQNMLPSLMAPLRTLTGTTE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ESKRDILFLFDGSVNVLGQFPAVRDFLYRIIEELDVKPDGTRVAIAQFSDDVRLESRFSEHQTKAEILNLVKKMKLKTGKALNLGYALDYALRNIFVRSAGSRIEDNVQQFLVLLVAGRSSDAVAGPASSLKQRGVVPFIFQAKNANPSELEQIVLSPAFILAAESLPKIGDLQSQIVSLLKAEQ--GSGPVSGEKDVVFLIDGSEGVRSGFPLLKDFVQRVVESLDVGPDRVRVALVQYSDRTRPEFYLNSHMDQQGVISAIRRLTLLGGPTPNTGAALEFVLRNILTSSTGSRIAEGVPQLLIVLTAEPSGDDVRGPSVVLKQGGAVPIGIGIGNADISEMQTISFIPDFAVAIPTFRELGTIQQVISERVIQLNREELSSLKPILTPSTGAGVGSKKDVVFLIDGSRNAGPEFQYIRTLIERIVEYLDIGFDTTRVAVIQFSEDSKMEFPLNAHFSKDEVQNAVRRLRPKGGSQVYIGNALEYVLKNIFQRPLGSRIEEGVPQFLVLISSGKSDDEVDDSAVELKQFGVAPLTIARHTDQEELVKISLSPEYVYSVSTFRELPRLEQKLLTPITTLTSQQIHQILASTRYPPSVVESDAADIVFLIDSSDAVKPDGIAHIRDFVSRIVRRLNIGPSKVRIGVVQFSNDVFPEFYLKTHKSQSSVLEAIRRLRFKGGSPLNTGRALEFVARNLFVKSAGSRIEDGVPQHLVLFLGGKSQDDVARHAQVISSSGIVSLGIGDRNIDRTDLQTITNDPRLVFTVREFRELPNIEERVMLSFGPSGATPQPPGVDLPSPSRPEKKKADIVFLLDGSINFRRDSFQEVLRFASEIVDTVYEDGDSIRVGLVQYNSDPTDEFFLRDFSTKRQIIDAINKVVYKGGRHANTRVGIEHLLRNHFVPEAGSRLDERVPQIAFVITGGKSVEDAQDVSLALTQKGVKVFAVGVRNIDSEEVGKIASNSATAFRVGSVQELSELSETVLETLHDAMHETLCPGVTDVSKACNLEVILGFDGSRDQNVFVSQKGLESKVDIILNRISQIQRISCSGNQLPTVRVSVMANTPSGPVEAFDFAEYQPELFEKFRNMRSQRPYVLTADTLKLYQNKFRQSSPDTVKVVIHFTDGADGDMADLYRASEELRQAGAQALILVGLERVANLERLMHLEFGRGFMYDRPLRLNLLDLDYELAEQLDNIAEKACCGVPCKCSGERGDRGPIGSIGPKGISGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFPGEKGELGEIGLDGLDGEEGDKGLPGSSGEKGSPGRRGDKGPKGDKGERGDVGIRGDPGDSGRDSQQRGPKGETGDIGPMGLPGRDGIPGSPGDPGKDGGSGRRGPAGAKGNRGGPGQPGFEGEQGTRGSQGPPGPIGPPGLIGEQGIPGPRGGGGTAGAPGERGRTGPLGRKGEPGEPGPKGSIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGTPGEPGADGPPGPKGIRGRRGNSGPPGATGQKGDPGYPGPSGHKGNRGDSVDQCALIQSIRDKCPCCYGPLECPVFPTELAFALDTSEGVTQDTFSRMREVLLGIVGDLTIAESNCPRGARVAVVTYNNEVTTEIRFADSKKKSALLDSIQNLQVALTSKQQSLETAMSFVARNTFKRVRSGFLMRKVAVFFSNKPTRASPQLREAVLKLSDAGITPLFLTSQEDRQLINALQINNTAVGHALVLPARRDLTDFLKNVLTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDIDLAFILDSSEATTLFQFNEMKKYIGYVIRQLDLSPDPKASQHFARVAVVQQSTYESVDNASVPPVKVEFSLTDYGAKEKLLDFLSRRMTQLQGTMGLGNAIEYTIENIFESAPNPRDLKIMVLMLTGDMQRQQLEEAQRAILQAKCKGYFFVVLGIGRKVNIKEVYSFASEPNDVFFKFVDKSTELNEEPLMRFGRLLPSFVSSENAFYLPPDLRKQCDWFQGDQPVKNGVKFGHKQINPPHTANSSLTSKVVTTMKPVTTTKPTAIVNLPPAKPAPARPAPAQPVLAKPDPAKPAQARPAPAKPASAKLVPPQPVHVQPAPAQTASVRPAPAKPAPPQPAAAKPVP-----AKPAVP----AQPAPPQPAAAKPVPAKPA-------------------VPAQPAPPQPAAAKPVPAKPAVPAQPAAAQ-----PMPAQPVLTKSAAVKPASANKPVAAKPVATNTATATARPALAAKPAAA-KPAATRPLAAAIRPVATKPEAPR-QQAKPAATKPATTKPLARVSREVQVSEVTENSARLHWERPEPSSSFFYDLTVTSAHDQSLVLRQNLTVTDRVIGGLLAGQLYHVVVVSYLQSQVRAIYQGSFNTKKTQPPPLQAAHRASSSTINLMVNTEPLFLTKTDICKLSRDAGTCVDFKLLWHYDLESKSCKRFWYGGCGGNENRFHSQEECEKMCSPDLLV---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P12111-1", "uniprot_id": "CO6A3_HUMAN", "id": "P12111-1", "name": "Collagen alpha-3(VI) chain", "aln": "MRKHRHLPLVAVFCLFLSGFPTTHAQQQQADVKNGAAADIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGENDFHFALVQFNGNPHTEFLLNTYRTKQEVLSHISNMSYIGGTNQTGKGLEYIMQSHLTKAAGSRAGDGVPQVIVVLTDGHSK-DGLALPSAELKSADVNVFAIGVEDADEGALKEIASEPLNMHMFNLENFTSLHDIVGNLVSCVHSSVSPERAGDTETLKDITAQDSADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYSTKAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPSSDEIRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNLVFTVPEFRSFGDLQEKLLPYIVGVAQRHIVLKPPTIVTQVIEVNKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSSLVFIPAEFRAAPLQGMLPGLLAPLRTLSGTPEVHSNKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQIAFNPSLVYLMDDFSSLPALPQQLIQPLTTYVSGGVEEVPLAQPESKRDILFLFDGSANLVGQFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLHPQIVNLLKSVHNGAPAPVSGEKDVVFLLDGSEGVRSGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQQVISERVTQLTREELSRLQPVLQPLPSPGVGGKRDVVFLIDGSQSAGPEFQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTIARNADQEELVKISLSPEYVFSVSTFRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPPAVESDAADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKTYRSQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQDDVSRFAQVIRSSGIVSLGVGDRNIDRTELQTITNDPRLVFTVREFRELPNIEERIMNSFGPSAATPAPPGVDTPPPSRPEKKKADIVFLLDGSINFRRDSFQEVLRFVSEIVDTVYEDGDSIQVGLVQYNSDPTDEFFLKDFSTKRQIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPEAGSRLDQRVPQIAFVITGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGKIASNSATAFRVGNVQELSELSEQVLETLHDAMHETLCPGVTDAAKACNLDVILGFDGSRDQNVFVAQKGFESKVDAILNRISQMHRVSCSGGRSPTVRVSVVANTPSGPVEAFDFDEYQPEMLEKFRNMRSQHPYVLTEDTLKVYLNKFRQSSPDSVKVVIHFTDGADGDLADLHRASENLRQEGVRALILVGLERVVNLERLMHLEFGRGFMYDRPLRLNLLDLDYELAEQLDNIAEKACCGVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDSIDQCALIQSIKDKCPCCYGPLECPVFPTELAFALDTSEGVNQDTFGRMRDVVLSIVNDLTIAESNCPRGARVAVVTYNNEVTTEIRFADSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTFKRVRNGFLMRKVAVFFSNTPTRASPQLREAVLKLSDAGITPLFLTRQEDRQLINALQINNTAVGHALVLPAGRDLTDFLENVLTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNASMPPVKVEFSLTDYGSKEKLVDFLSRGMTQLQGTRALGSAIEYTIENVFESAPNPRDLKIVVLMLTGEVPEQQLEEAQRVILQAKCKGYFFVVLGIGRKVNIKEVYTFASEPNDVFFKLVDKSTELNEEPLMRFGRLLPSFVSSENAFYLSPDIRKQCDWFQGDQPTKNLVKFGHKQVNVPNNVTSSPTSNPVTTTKPVTTTKPVTTT------------------------TKPVTTTTKPVTIINQ-----------------PSVKPAAAKPAPAKPVAAKPVA--------------------TKMATVRPP----------------------------------------------------------------------VAVKPATAAKPVAAKPAAVR-----------------------PPAAAAAKPVATKPEVPRPQAAKPAATKPATTKPMVKMSREVQVFEITENSAKLHWERAEPPGPYFYDLTVTSAHDQSLVLKQNLTVTDRVIGGLLAGQTYHVAVVCYLRSQVRATYHGSFSTKKSQPPPPQPARSASSSTINLMVSTEPLALTETDICKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVCAPVLAKPGVISVMGT", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*************.*:***:. **** *:. *:***************:** :********:::***********:**:********:****:*::..*::.**:****:.*:********:**************:*****:**************::**.****::.****:.:*.:.**: **:****************.****.***.*:******:**.* * ***********.*::****.******:**:**:***:***:*:**:****::****.***:*.*******:**:****.**** ***:* * ***:********.* ***********:* * ****.*** **:*********:*:****** *****************:.:**.***: : . .**********:**************:************ ::****:***************:*::*.*:.*:*:***************:*******.**:**** ************: ******.****:*:***************:*******************:***:******** **.**:** * *:* * ...* *.*:*********:.**.***::******:*:***:*************:*.*:** **** *********:******* *: :******* :***:*********************** *****.***********:*:**::***************:********* ***:**********:**:::********...**************:.::***:******************.***:*****************::** .**:******::********:****************************.*********:*.**** ****:***:********:**************************:* *****..** ** *: *. *******************************.**************:****************:***************:*********:**:*** ****.*******:***************************:*******************************.********* *******************.:*****:***************:***:***** *******::*:***..: *******:************* ****:::****.****:***** ****:* *********:**************:***:****:*** *.:**********.******::********************************************:***************.**************************************************:***********:*************.*********:*:**************:.*:***:*********:****:*****:**.**:.**:** *****.*****:****************:***.** ***********.****.**:**************************. ***************************************.***** :*..**************** .***********:* :******:*********:*****************************.****.***:*:*.**.**********************************:**.***.*:********** ******************.********:**** **:.* ******************** ****:******************** *** ***:*********************.******************:******:*:*************.*::****:*****************::. *****:*:*************:****:***** ******* **.********:************:******:: .:*******.*********************:****:***********::**********************.* *****.**:************.** *****:*:* *:...** **: *** ********.: . :**. : . * .*.:**.*****.:..****.. .: *:.:* .*:***:* *******.*.. * .** :*******.** *************:.::****** *:*****:*****.**...:****************:***************** ***.**.**:***** *:***.***:*** *.*: **********.**** **:******.:* *** ** * *:** ::*** ************:* **:****:*:* * ", "identical_positions": 2093, "similar_positions": 359, "identity": "62.82%" }, { "cls_id": "homologset.agr.RGD:1308705", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZJG8-1", "uniprot_id": "D3ZJG8_RAT", "id": "D3ZJG8-1", "name": "", "aln": "MGDMKTPDFDDLLAAFDIPDPTSLDAKEAIQTPSEENESPLKSSGMCMDENVSLSHSGSVPDVPAVSVIVKNTSRQESFEAEKDHITP---SLLHNGFRGSD--LPPDSHHCGKFDSTFINGD----SARSFTSKLEPSKSEPLPT-FNQFSPISSPEPEDPVKDNGFGIKSKHSDS-YFPPPP--GTVGGPVLEALAKFPVPELHMFDHFCKKEPKPEPLPLESQQEHEQGGQKVVEPHKDLDSSRFFGEALEFNSHPSNSIGEPKKLVPELSACSSVPPRQRLKPAHSKLSSCVAALVALQAKRVANVTKEDQPGHIKDSSGPTKEGSKGSPKMPKSPKSPRSPLEATRKNIKPSDSPRSICSDSSSKGSPSVAASSPPAIPKVRIKTIKTSSGEIKRTVTRVLPDP--DDPS----ESPAGGTSAEVPSEVPGDEGSAMPVEEHFSEAGIDSGSPQGDRKGGENMINKTSDSLSPCRTSGPRVPKGSALNSQASKKQQSTALQASTPAPASLLPKAVHLANLNLVPHSVAASVTAKSSAQRRSQPQVTQ----MTVPLVHQVKKAAP--------LIVEVFNKVLHSSNPVPLYAPNLSPPADSRIHVPASGYCCLECGDAFALEKSLSQHYSRRSVHIEVLCTLCSKTLLFFNKCSLLRHARDHKSKGLVMQCSQLLVKPISADQMFVAAPVNSTAPATPAASSSPKPSPTLDNASPVIPALPLYPDPVRLIRYGTKCPECHKQMRDYMVLATHFQRTTEETEGLTCQVCQMLLPNQCSFCAHQRIHAHKSPYCCPECGVLCRSAYFQTHVKENCLHYARKVGYRCIHCGVIHLTLALLKSHIQERHCQVFHKCAFCPMAFKTASSTMDHSTTQHPTQPHKPSQLIYKCSCEMIFNKKRHIQQHFYQNVSKTQAAVFKCPECPLLFLQKPELMQHVKNTHG-VPRNVEELSSLQSSTDTSSNRPGSRAPTEPPATNVATRGSSLTAGRWGRPDAHRRAEARPRMRNTGWTCQECQEWVPDRESYVSHMKKSHGRTLRRYPCRQCEQSFHNPSSLRKHIRNNHDTVKKVYTCGYCSEDSPSFPRPSLLESHISLMHGIRNPDLSQTSKVK-HAGGHSPQVNHLKRPVSRMADAPGTSNGATASSTKRHKPLFQCARCTFSTDSELEFQSHIPQHQVDSSTAQCPLCGLCYTSARSLSRHLFIVHKVRGQEEGGEE---IVQVKVEATDPEACSGEEVAVKTGENGLEECVSEPLVADIEPRRSLGLAVDEDSAQDPQNQPQASQDQNSHALSPQV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BHZ4-1", "uniprot_id": "ZN592_MOUSE", "id": "Q8BHZ4-1", "name": "Zinc finger protein 592", "aln": "MGDMKTPDFDDLLAAFDIPDPTSLDAKEAIQAPSEENESPLKSSGMCIDENVSLSHSGSAPDVPAVSVIVKNTSRQESFEAEKDHIAP---SLLHNGFRGSD--LPPDSHHCGKFDSTFINGD----SARSFTSKLEPSKSEPLPT-FNQFSPISSPEPEDPVKDNGFGIKSKHSDS-YFPPPP--GTVGGPVLEALSKFPVPELHMFDHFCKKEPKPEPLPLESQQEHEQGGQKVVEPHKDLDSSRFFGEALEFNSHPSNSIGEPKKLAPELSACSSVPPRQRLKPAHSKLSSCVAALVALQAKRVANVTKEDQPGHTKDSSGPTKEGSKGSPKMPKSPKSPRSPLEATRKSIKPSDSPRSICSDSSSKGSPSVAASSPPAIPKVRIKTIKTSSGEIKRTVTRILPDP--DDPSKSPAESPAGSTITEAPSEAPGDEGTAMPVEEHFSEAGIHSGSPQGDRKGDENMI-KTSDSSSPCRISGSRVPKGSALNSQASKKQQSTAPQASTPA-ASLLPKAVHLANLNLVPHSVAASVTAKSSAQRRSQPQVTQ----MTVPLVHQVKKAAP--------LIVEVFNKVLHSSNPVPLYAPNLSPPADSRIHVPASGYCCLECGDAFALEKSLSQHYSRRSVHIEVLCTLCSKTLLFFNKCSLLRHARDHKSKGLVMQCSQLLVKPISADQMFVAAPVNSTAPATPAASSSPKPSPTLDNASSVIPALPLYPDPVRLIRYGTKCPECHKQMRDYMVLATHFQRTTEETEGLTCQVCQMLLPNQCSFCAHQRIHAHKSPYCCPECGVLCRSAYFQTHVKENCLHYARKVGYRCIHCGVIHLTLALLKSHIQERHCQVFHKCAFCPMAFKTASSTMDHSTTQHPTQPHKPSQLIYKCSCEMVFNKKRHIQQHFYQNVSKTQAGVFKCPECPLLFLQKPELMQHVKNTHG-VPRNVEELSSLQSSTDTSSNRPGSRAPAEPPATNVAARGSSLTAGRWGRPEAHRRAEARPRMRSTGWTCQECQEWVPDRESYVSHMKKSHGRTLKRYPCRQCEQSFHNPSSLRKHIRNNHDTVKKVYTCGYCTEDSPSFPRPSLLESHISLMHGIRNPDLSQTSKVR-HPGGPSPQVNHLKRPVSRMADAPGTSNGATVSSTKRHKSLFQCAKCTFATDSELEFQSHIPQHQVDSSTAQCLLCGLCYTSTSSLNRHLFIVHKVRDQEEGGED---IVEVKVEAPDSEACSGEEVAMETKENGLEECASEPLVTDLGGQQ--GLALDEDSAQDPQNQPQASQDQNSHALSPQV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92610-1", "uniprot_id": "ZN592_HUMAN", "id": "Q92610-1", "name": "Zinc finger protein 592", "aln": "MGDMKTPDFDDLLAAFDIPDPTSLDAKEAIQTPSEENESPLKPPGICMDESVSLSHSGSAPDVPAVSVIVKNTSRQESFEAEKDHITP---SLLHNGFRGSD--LPPDPHNCGKFDSTFMNGD----SARSFPGKLEPPKSEPLPT-FNQFSPISSPEPEDPIKDNGFGIKPKHSDS-YFPPPLGCGAVGGPVLEALAKFPVPELHMFDHFCKKEPKPEPLPLGSQQEHEQSGQNTVEPHKDPDATRFFGEALEFNSHPSNSIGESKGLARELGTCSSVPPRQRLKPAHSKLSSCVAALVALQAKRVASVTKEDQPGHTKDLSGPTKESSKGSPKMPKSPKSPRSPLEATRKSIKPSDSPRSICSDSSSKGSPSVAASSPPAIPKVRIKTIKTSSGEIKRTVTRILPDP--DDPSKSPVGSPLGSAIAEAPSEMPGDE---VPVEEHFPEAGTNSGSPQGARKGDESMT-KASDSSSPSCSSGPRVPKGAAPGSQTGKKQQSTALQASTLAPANLLPKAVHLANLNLVPHSVAASVTAKSSVQRRSQPQLTQ----MSVPLVHQVKKAAP--------LIVEVFNKVLHSSNPVPLYAPNLSPPADSRIHVPASGYCCLECGDAFALEKSLSQHYGRRSVHIEVLCTLCSKTLLFFNKCSLLRHARDHKSKGLVMQCSQLLVKPISADQMFVSAPVNSTAPAAPAPSSSPKHGLTSGSASPPPPALPLYPDPVRLIRYSIKCLECHKQMRDYMVLAAHFQRTTEETEGLTCQVCQMLLPNQCSFCAHQRIHAHKSPYCCPECGVLCRSAYFQTHVKENCLHYARKVGYRCIHCGVVHLTLALLKSHIQERHCQVFHKCAFCPMAFKTASSTADHSATQHPTQPHRPSQLIYKCSCEMVFNKKRHIQQHFYQNVSKTQVGVFKCPECPLLFVQKPELMQHVKSTHG-VPRNVDELSSLQSSADTSSSRPGSRVPTEPPATSVAARSSSLPSGRWGRPEAHRRVEARPRLRNTGWTCQECQEWVPDRESYVSHMKKSHGRTLKRYPCRQCEQSFHTPNSLRKHIRNNHDTVKKFYTCGYCTEDSPSFPRPSLLESHISLMHGIRNPDLSQTSKVK-PPGGHSPQVNHLKRPVSGVGDAPGTSNGATVSSTKRHKSLFQCAKCSFATDSGLEFQSHIPQHQVDSSTAQCLLCGLCYTSASSLSRHLFIVHKVRDQEEEEEEEAAAAEMAVEVAEPEEGSGEEVPMETRENGLEECAGEPLSADPEARRLLGPAPEDDGGHNDHSQPQASQDQDSHTLSPQV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B5T2-1", "uniprot_id": "A0A8M2B5T2_DANRE", "id": "A0A8M2B5T2-1", "name": "", "aln": "MGDMKTPDFDDLLAAFDIPDATSLDAKEAIHGNQDEGDGHLKHSEMCMDTTVSIPHPVPTADAPAVSVIVKNTSRQNSYENLVEKESPHLGHLLQNGFKSSVGSLETHPSSYPRLDSSSVNGENFNHSLEKTPVLYKPEKGPTLSESVSQFSPISSPESED-IQSNGIDDCPKSAETSYFPSDSLFTSPTVTVLDYLEKADVPDSGCNYSHCGSKGVDDLESDSSSFKDDLVGKNADSATKS-DCS----QDCRTNTYPT------------LETNS--PSRPCAKAHTSRLSSCIDALAALNPKKDSGGHIN-----SKDIPVTPKETVKISQKIPISPRSPKSPLEVVKRFTKQPDSPMSICSDSSGKASPAVATGSPPAIPRVRIKTIKTSSGEIKRTVTSILPDSETEDLMSPFGSSPSQSSVEEAFSKTLPPN----HSTDIISEVIFEDGSQEASKMASSGSTKSVRSSKSPQIQNIGHALKTTEGGTQQRK---ATSAQIGSSANTNYLPKALHLANLNLVPHSVAASVTARSSTNRQEPSQLSSSMVCSSVPLVHQVKKVSPNTRAVVPNTAAGTLNRLLNYSNPVPTYVPNLSPPPGTNIKLPTQGYCCLECGDSFGLEKSLAYHYSRRSVHIEVACTHCSKTLVFFNRCALLAHARDHKNKGMVMQCTQLFMKPIAVDQMLVPTKT-SLQSAIQIPCGN-----TTTEPSKGQVVLPLYPD--NVIRNGSKCLECNKQISDYTALARHYQKSSED-EGLICKVCSMLLPNKCSYRAHQRIHTHKSPYCCPECGALSRSVDIQKHVKENCLHYTRKIGYSCLHCEMLFMSLSHLKSHIEEKHCEVFYKCTTCPVAFKSYDGCLMHVKNKHGGSEPN-HQVIYKCSCETVFKRRQLLYQHFHN-----RICVFKCPECTSLFPEKLPLVQHFKTIHGGVFRGEAEKS----SKTTETSLPKNLQPSLTKAGNEACVKEMENS-------TARKSSAEAGIKNTGWTCGVCLLWVPDRETYVSHMKTSHGKSLKRQPCRLCERSFNSPMSLKRHIRNDHNGKKKVYTCWYCTSERMSFTEHSLLKNHISLMHGVKNPDFSQMAKLESQEVGKIRSERPKKRRAEHPDGVKGNGETSHNTPSKRHKPLYRCAKCGFTSEAQAQFQEHIPQHKSDSNTPQCQHCGLCFTSQLALSRHLFIVHKVKEPEE-HED----FKDGKEREISTDLSDKTVPLLRNKTGLSTAEDQLGLHNVPTDTDYNTQTSENSGLEDKKA----------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "********************.*********: .:*.:. ** . :*:* .**:.*. ...*.*************:*:* :: :* **:***:.* * ... ::**: :**: * .. . :* *. .*. ..*********.** ::.**:. .* ::: ***. : .**: * * **: .* .: : . *. :.: *::. .. *. *.: : . *::*: * : * *.* *. *:****: **.**:.*: :. : ** . ..** * * *:* **:**:****..:: * .*** *******.*.**:**:.******:****************** :***. :* ** .: *. *: : : :.*. ..** :. : .... .. .* ** . :. * : .:* * :*: * .: * :. ****:******************:**.:*:. .*::. :*********.:* . .:*::*: ***** *.******..:.*::*:.*********:*.*****: **.******** ** *****:***:*:** ******.**:****:**::***:.***:*.: . * .* .... * ..* .****** .:** . ** **:**: ** .** *:*:::*: *** *:**.*****:**: ******:***********.*.**. :*.*********:**:** *:** ::.::*: *****:*:**:**:**: **:***: .. * .:* . . *:******* :*:::: : ***:: : *******. ** :* *:**.*. ** * *. * * * *.:. * . *: . * . * . : : *: .*.. ::.***** * ******:******.***::*:* *** **:**:.* **::****:*: **.*** **:.: **.. ***:.*******::***:** :*:. * . . ** .. .. *..: : :.:****.*::**:* *:::: :**.*****: **.*.** ****:** :*.*********: ** *: : * . *.: *.: :.**. . .: : . .::.. : :. ", "identical_positions": 548, "similar_positions": 354, "identity": "42.22%" }, { "cls_id": "homologset.agr.RGD:1308706", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A288-1", "uniprot_id": "A0A8I6A288_RAT", "id": "A0A8I6A288-1", "name": "", "aln": "MKGRAQHHGSAHLCVGWWSLVGATPPSERSTALEGVAMGLPWKGRRLLLQPARSPAHAHARLHGRVAAGVRTRCVEQRSQGAASTAAQEGSMSATRAKKVKMATKSCPECDQQIPVACKSCPCGYIFISRKLLNAKHSEKSPPSTENKHEAKRRRTERVRREKINSTVNKDLENRKRSRSNSHSDHIRRGRGRPKSSSAKKHEEEREKQEKEIDIYANLSDEKAFVFSVALAEINRKIINQRLIL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CR55-1", "uniprot_id": "CP087_MOUSE", "id": "Q9CR55-1", "name": "UPF0547 protein C16orf87 homolog", "aln": "-------------------------------------------------------------------------------------------MSATRAKKVKMATKSCPECDQQIPVACKSCPCGYIFISRKLLNAKHSEKSPPSTENKHEAKRRRTERVRREKINSTVNKDLENRKRSRSNSHSDHIRRGRGRPKSSSAKKHEEEREKQEKEIDIYANLSDEKAFVFSVALAEINRKIINQRLIL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6PH81-1", "uniprot_id": "CP087_HUMAN", "id": "Q6PH81-1", "name": "UPF0547 protein C16orf87", "aln": "-------------------------------------------------------------------------------------------MSATRAKKVKMATKSCPECDQQVPVACKSCPCGYIFISRKLLNAKHSEKSPPSTENKHEAKRRRTERVRREKINSTVNKDLENRKRSRSNSHSDHIRRGRGRPKSASAKKHEEEREKQEKEIDIYANLSDEKAFVFSVALAEINRKIINQRLIL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DGQ4-1", "uniprot_id": "CP087_DANRE", "id": "Q6DGQ4-1", "name": "UPF0547 protein C16orf87 homolog", "aln": "-------------------------------------------------------------------------------------------MSTNKVKKVKMATKSCPECDQQIPVACKSCPCGYVFISRKLLNAKLNERS--GVMDKLEDKRRRTERIRKEKINLTSTSDMENRRRSRTNSHSDPIRRGRGRPKTVGLKKQEEEKEKQEREVDIYANLSDEKAFVFSVALAEINRKILGQRLIL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **:.:.****************:***********:********** .*:* .. :* * *******:*:**** * ..*:***:***:***** *********: . **:***:****:*:*************************:.*****", "identical_positions": 117, "similar_positions": 26, "identity": "47.76%" }, { "cls_id": "homologset.agr.RGD:1308707", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZUK2-1", "uniprot_id": "A0A8I5ZUK2_RAT", "id": "A0A8I5ZUK2-1", "name": "", "aln": "--MMTSVGTNRARGNWEQPQ--------------------------------NQNQTQHKQRPQATAEQIRLAQMISDHN-DADFEEKVKQLIDITGKNQDECVIALHDCNGDVNRAINVLLEGNPD--THSWEMVGKKKGVSGQKDGGQTES------NEEGKENRDR--DRDYSRRRGGPPRRGRGASRGRECMHGALSKPAVVRGQENGLDGTKSGGPSGRGTDRGRRGRGRGR-GSSGRRGGRFSAQGMG---------------TFNPADYAEPANTDDNYGSSSGNTWNNTGHFEPDDGTRLDFIGVEGSNYPRKFETAPGMIHPGAWRTATEEWGTEDWNEDLSETKIFTASNVSSVPLPAENVTITAGQRIDLAVLLGKTP-SSMENDSSNLDPSQAPSLAQPLVFSNSKQN-AISQPASGNTFSHHSMVSMLGKGFGDVGEAK---GGSTTGSQFLEQFKTAQALAQLAAQHSQSGSTTT--SSWDMGSTTQSPSLVQYDLKSANDSTVHSPFTKRQAFTPSST---MMEVFLQEKPPAVATSTAAPPPP----------SSPLPSKSTSAP--QMSPGSSDNQSSSPQPAQQ-KLKQQKKKTSLTSKIPALAVEMPGS---ADISGLNLQFGALQFGSEPVLSDYESTPTTSASS--SQAPS-------------------SLYTSTASESSSTVSSNQSQESGYQSGPIQSTTYTSQNNAQGPLYEQRSTQTRRYPSSISSS--------------------------PQKDLTQAKNGFSSVQATQLQTTQSVEGATGSAVKSE-------SPSTSSIPSLNETVP-AASLLTTASQHSSSLSGLSHSEEIPNT---TTTQHSSALSTQQNTLSSSTSSGRTSTSTLLHTSVESEANLHSSSSTFSTTS---------------------STVSAPPPVVSVSSSLNSG---------------------------------------SSLG---LSLGSNSTVT--------ASTRSSVATT---------------SGKAPPNLPPGVPP----------------LLPNPYIMAPGLLHA----YPPQVYGYDDLQMLQTRFPLDYYSIPFPTPTTPLTGRDGSLASNPYSG-DLTKFGRGDASSPAP---ATTLAQPQQNQTQTHHTTQQTFLNPALPPG-YSYTSLPYYTGVPGLPSTFQYGPAVFPVAPTSSKQHGVNVSVNASATPFQQPSGYGSHGYNT----------------------------------------------------GVSVTSSNTGVPDISGSVY------SKTQQSFEKQGFHSGTPAASFNLPSALGSGGP-------INPATAAAYPPAPFMHILTPHQQP----------HSQILHHHLQQDGQTGSGQRSQTSSIPQKPQTNKSAYNSYSWGAN---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80X50-1", "uniprot_id": "UBP2L_MOUSE", "id": "Q80X50-1", "name": "Ubiquitin-associated protein 2-like", "aln": "--MMTSVGTNRARGNWEQPQ--------------------------------NQNQTQHKQRPQATAEQIRLAQMISDHN-DADFEEKVKQLIDITGKNQDECVIALHDCNGDVNRAINVLLEGNPD--THSWEMVGKKKGVSGQKDGGQTES------NEEGKENRDR--DRDYSRRRGGPPRRGRGASRGRE-----------FRGQENGLDGTKSGGPSGRGTDRGRRGRGRGR-GSSGRRGGRFSAQGMG---------------TFNPADYAEPANTDDNYGNSSGNTWNNTGHFEPDDGTRLDFIGVEGSNYPRKFETAP-----GAWRTATEEWGTEDWNEDLSETKIFTASNVSSVPLPAENVTITAGQRIDLAVLLGKTP-SSMENDSSNLDPSQAPSLAQPLVFSNSKQN-AISQPASGSTFSHHSMVSMLGKGFGDVGEAK---GGSTTGSQFLEQFKTAQALAQLAAQHSQSGSTTT--SSWDMGSTTQSPSLVQYDLKSANDSTVHSPFTKRQAFTPSST---MMEVFLQEKPPAVATSTAAPPPP----------SSPLPSKSTSAP--QMSPGSSDNQSSSPQPAQQ-KLKQQKKKTSLTSKIPALAVEMPGS---ADISGLNLQFGALQFGSEPVLSDYESTPTTSASS--SQAPS-------------------SLYTSTASESSSTVSSNQSQESGYQSGPIQSTTYTSQNNAQGPLYEQRSTQTRRYPSSISSS--------------------------PQKDLTQAKNGFSSVQATQLQTTQSVEGATGSAVKSE-------SPSTSSIPSLNETVP-AASLLTTANQHSSSLSGLSHTEEIPNT---TTTQHSSALSTQQNTLSSSTSSGRTSTSTLLHTSVESEANLHSSSSTFSTTS---------------------STVSAPPPVVSVSSSLNSG---------------------------------------SSLG---LSLGSNSTVT--------ASTRSSVATT---------------SGKAPPNLPPGVPP----------------LLPNPYIMAPGLLHA----YPPQVYGYDDLQMLQTRFPLDYYSIPFPTPTTPLTGRDGSLASNPYSG-DLTKFGRGDASSPAP---ATTLAQPQQNQTQTHHTTQQTFLNPALPPG-YSYTSLPYYTGVPGLPSTFQYGPAVFPVAPTSSKQHGVNVSVNASATPFQQPSGYGSHGYNT----------------------------------------------------GVSVTSSNTGVPDISGSVY------SKTQQSFEKQGFHSGTPAASFNLPSALGSGGP-------INPATAAAYPPAPFMHILTPHQQP----------HSQILHHHLQQDGQTGSGQRSQTSSIPQKPQTNKSAYNSYSWGAN---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14157-2", "uniprot_id": "UBP2L_HUMAN", "id": "Q14157-2", "name": "Ubiquitin-associated protein 2-like", "aln": "--MMTSVGTNRARGNWEQPQ--------------------------------NQNQTQHKQRPQATAEQIRLAQMISDHN-DADFEEKVKQLIDITGKNQDECVIALHDCNGDVNRAINVLLEGNPD--THSWEMVGKKKGVSGQKDGGQTES------NEEGKENRDR--DRDYSRRRGGPPRRGRGASRGRE-----------FRGQENGLDGTKSGGPSGRGTERGRRGRGRGR-GGSGRRGGRFSAQGMG---------------TFNPADYAEPANTDDNYGNSSGNTWNNTGHFEPDDGT-------------------------SAWRTATEEWGTEDWNEDLSETKIFTASNVSSVPLPAENVTITAGQRIDLAVLLGKTP-STMENDSSNLDPSQAPSLAQPLVFSNSKQT-AISQPASGNTFSHHSMVSMLGKGFGDVGEAK---GGSTTGSQFLEQFKTAQALAQLAAQHSQSGSTTT--SSWDMGSTTQSPSLVQYDLKNPSDSAVHSPFTKRQAFTPSST---MMEVFLQEKSPAVATSTAAPPPP----------SSPLPSKSTSAP--QMSPGSSDNQSSSPQPAQQ-KLKQQKKKASLTSKIPALAVEMPGS---ADISGLNLQFGALQFGSEPVLSDYESTPTTSASS--SQAPS-------------------SLYTSTASESSSTISSNQSQESGYQSGPIQSTTYTSQNNAQGPLYEQRSTQTRRYPSSISSS--------------------------PQKDLTQAKNGFSSVQATQLQTTQSVEGATGSAVKSD-------SPSTSSIPPLNETVS-AASLLTTTNQHSSSLGGLSHSEEIPNT---TTTQHSSTLSTQQNTLSSSTSSGRTSTSTLLHTSVESEANLHSSSSTFSTTS---------------------STVSAPPPVVSVSSSLNSG---------------------------------------SSLG---LSLGSNSTVT--------ASTRSSVATT---------------SGKAPPNLPPGVPP----------------LLPNPYIMAPGLLHA----YPPQVYGYDDLQMLQTRFPLDYYSIPFPTPTTPLTGRDGSLASNPYSG-DLTKFGRGDASSPAP---ATTLAQPQQNQTQTHHTTQQTFLNPALPPG-YSYTSLPYYTGVPGLPSTFQYGPAVFPVAPTSSKQHGVNVSVNASATPFQQPSGYGSHGYNT----------------------------------------------------GVSVTSSNTGVPDISGSVY------SKTQQSFEKQGFHSGTPAASFNLPSALGSGGP-------INPATAAAYPPAPFMHILTPHQQP----------HSQILHHHLQQDGQTGSGQRSQTSSIPQKPQTNKSAYNSYSWGAN---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B5X1-1", "uniprot_id": "A0A8M2B5X1_DANRE", "id": "A0A8M2B5X1-1", "name": "", "aln": "--MMTSVGGSRARGNWEQTQGQ------------------------------TQSQSQHKQRPQATAEQIRLAQMISDHN-DADFEEKVKQLVDITGKDQDESMIALHDCNGDVNRAINVLLEGSPD--TDSWEMVGKKK-VSGQKESAQTDG------GDEGKENRERGGERDVARRRGGAPRRGRGASRGRE-----------FRGQENGLDGAKAGGVAGRGTERGRRGRGRGRAGGAGRRGGRFSAQGMGQIDKGPRYDFSGDESTFNPADYTEPAQTEESY--TSGSTWSNTGNLEPEDGNRLEFTGGEGTNYPLKFDSAP-----GAWRTATEEWGTEDWNEDLSETKIFTASSVASMPIPQENVTITAGQRIDLAVLLGKTPPSSSEAEPASLEGPQPQSLSQSLVFSNSKQTSSLSQSSSSAPYSQHNMVSMLGKGFGDVGDPKTTTGGSTTGSQFLEQFKTAQALAQLAAQHSQSGPPNAGPSTWDTSPSALG----QYDMKPQTEP-VHSPFTKRQPYQPASTTTSMMDAFLQDKTTGPSSTSALPPQSTQASSLAQAITTPVSKPMGAAPGQQNSSSPADPQASSPLPLQQHKLKQQKKRASITTKIPALAVEMPGS---ADISGLNLQFGALQFGSEPVLPEYDASAAVATTTPGNQGQN-------------------SLYTSASNEQATALS----------------------NPSQMELYESRANQTRRYPPSVSSS--------------------------PQKDM-QTKNGFS-----SIQTSQSLEAAAGSAVPVKPVSESVVPPSVSNMVSLADPSSGPTSLLTTSNQTP--LSALSHEDVSPSS---LATQHNNSLSTQQNSLAP--SSVRTSNTSLLHP-VDGDSSLHSSSFSVSAVAP--------------------SSVPPPSSITSVAPVSHSGPVVPPSS-------------------------VSLVSTQSSMGPVSLAMGLNNAVVSMVPPSAAASSSSSAASASAAPSSASLSRSTAASGKAPPNLPPGVPP----------------LLPNPYIMAPGLLHP----YPPQVYGYDDLQMLQTRIPLDYYSIPFATPTTALTGREGGLTSNPYSAGDLSKFGRNDASSPAP---ATTLAQPQQTQTQTHHTTQQPFLNPALPPG-YSYTSLPYYTGVPGLPNTFQYGPAMFPVAPTSSKQHGVNVGVNASATAFQQASGYGSHGYSTGYEDLGQASAGSGDFCKGGYSTAVAAAAAAAAAAAAASAQNKPASSVTGPGVGVSVTSSNTGVPDISGSVY------TKT-QSFEKQGFHTGTPSASFSLPSALGSAGP-------INPPAAAGYAPAPYMHILTPHQQP----------HSQMLHHHLQQDGQSGSGQRSQNASIQQKSQINKSGYNSYNWGGN---------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q86S05-1", "uniprot_id": "LIG_DROME", "id": "Q86S05-1", "name": "Protein lingerer", "aln": "MSTQTRSGGGGGGGHARNQKKSNASNSGGGGTGHHDGVSHAAAAGKKGGQDASKTDKPEKAQPKATTEQLRIAQITNSTTEDPQINEKVLLLLTMTQRSEEEVCCALNECDYDLEAAANFLIEELPQGAFAKYEKKRKNKAANNTADGAAGDGDWADGNGNADRREKSRNRSSNRGGTRGSSDSRGWRGRETRENERNQRESREPWSGQNAGQD--RGDDRANDNYRGQRNGGGRSGPGGGGRGGGFVSRSGRG---------------GGRMGGRTGGPRGDRGSGGPGGAYGSGRGGNANEDHHEVELWDNTIAQNAEKQQ--------QAHDDAWGDWNNEEYEGSLKDSKVFTTSNLATQSAAN-VVSGTGASVTAVPAAAGTEISAPPGLEHQLVQQGSHLEESSSSGPAAVTPPATLSGSATTPLLQYSAAVSNPPPQLQSQGTQS----GAGTGASAAAGGGAGSTPSSFVSASPDTFSSAAS-AAATLVHQAQKQQQLQQQTTPIKPSATLSVEQSQYFNSLASQGVSPGSVPVQSAPAGYAQNPVAAYSQTS--------TSVGVSQYPNTYANVFASGTAAGAGTAEQSQQQPQIRRARVKLPPPSKIPASAVEMPGDNALNNIGYLDVQFGALDFGTDDGFEPLPEKVGSGFSIDGQQQQQQPDDYQSKSQQQQQVTLAAGLQSSQISDALNAAGYTSRSTSQQQQGVSSAVNATIDQLTKSDPYGQTGGSGNAYQNAYQSSGASKTASGFPTTAPGGYSSSTYANVQSSVANSYQQQGYGSYQPSSYQQQAGSGAQSGTGAVSGGGGTATQNIPVGGSSSQNSTSGNASSAYLTSGYSTPQSAYQSSQSVYGNTGLSNSSGFSGSASNASSQYANFSASAKLKDATTASSAAHYDSVSTSSGVSSNSGSTGNGGVVSGQTGANQAAVSNNNSVSGSSSVSNVTAGVASGNVAGVGGGVSQSGVSSGVGVPGGSASSVGVNVNNNSSSASSVGAATVAQTATGTTAAVLASLTNKNTSSSNSSGSGGSAATTTG---NASGQGAGASTGGVGSSSGAGGAGSGGGSGSGLVPTNIQMVSQYIQTGLPYYQQPVYSYEELQMMQQRVPHVQGYYDLNYPPASLGAGRDNLGSVTYSAMNDGRFARTDNNSSPVGNVSSTMSQQAGSSAPMLNVPYAYFYGGNVMPGSFQYGTPAIYPQIPAANTASGQ---QFPKPSYSAGYGSTSYDTLSQTTQDYSKGGYSSSVNQQS------------------------------------------------KTQTVSNQSQAGTGSDLTSSMYGKGHVALNKVNSYEKQSFHSGTPPP-FNMPNTQTAGGTSAQPYGMYLPMPAAGHHNMIHQPIHQVHSELPLQVVVGGGTESHVLIHGNVNGPQVTYHRIWQTEPVQCQNQLVAAHCNNFEPNIDCCVHDNNNDLSFFAD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * . . *: .: : .:.:. .* :*:**:**:*:**: .. . *.:::*** *: :* :.::* **::*: *:: * *.*:* *: .:* *:* ... :.. :. .: .:.::.* . : . **.. ** . . ** **: * * :... :. . *.* **. *..** ** .* .* * . .. : .. : . ..* .. * :* * * :*..*::: .*.::*:**:*.::: . . *: *... :.. *. :. : :: . . :.. : . ::* .:: . ** : . * . *: **:. :..: :.:.: .:: .. : :: : * : . . . . * .: :* .. :*. ... : ... . :: . : :...: .:: . ** :::: : : . .:**** ******. :*. *::*****:**:: : . . : .* . .* :* .: .: . : :: * . . . . * : .** .. ::*:. . * . . :*:.. .... . .. .:* *:. . . * . .: :: ...: *. .. : :* : . :: . .. :: **. : .: : .:*. ...: .*:. ** **:* :: ..:.. .: ** :: **:.. . ** . *:*. *.. ::. * **.*::***:* *.* : *.:.* . ..* * .**. : :*.* * .*.. ::*::* ..: :.. * . : ** :.* : . *. :*. .: ** .. *: ... .. :.:* . .**.* . ** *. .*::.*:* :. :*:***.**:***.. *.:*.: :.*. * .**.: . * *.: .*::* * :. * : *. .: : * : *.:. . : ", "identical_positions": 199, "similar_positions": 419, "identity": "13.55%" }, { "cls_id": "homologset.agr.RGD:1308708", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GDP5-1", "uniprot_id": "A0A8I6GDP5_RAT", "id": "A0A8I6GDP5-1", "name": "", "aln": "----MTSAAPAKKPYRKAPPEHRELRLETPVS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RLEQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QEPLTDAERMQLLQQENEELRRRLASATRRTEALERELEIGQDCLELELGQSREELDKFKDKFRRLQNSYTASQRTNQELEDKLHALASLSHSWIFAIKKAEMDRKTLDWEIVELTN-KLLDARNTINKLEELNERYR-------------------------------LDCNLAVQLLKCNKSHFRNHKFADLPCELQDM------VRKHLRSGQ----EVASPSRSPSSSLAPGAVVPTSVIARVLEKPESLLLNSDQSGS--AGRPLAEDVFVHVDMSG------------GDPASPPAPGSPSPQ-LNGECCSVSIAGDSPEEELPLPAFDKLSPYPTPSPPHPLYPGRKVIEFS-EDKIR-------IPRNSPLPNCTYATRQAISLSLVEDGGERAHCS-PVPSSPASAGG-------------SPYHQPSP------------------ARSAPSAPASSASSEEDLLASWQRAFVDRTPPP--AAVVQRTAFGRDALPELQLHFPPG---------------HSTAPLPSPRHERG-----------LVLPSEPDSAFPREEEEEMLNLPVSPEEE------------------RQSLLPDKEDTGEGPSPSHVDGRAWPLS-------------------SSSRPQRSPKRMGVHHLHRKDSLTQAQEQGTLLS-----------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DCD5-1", "uniprot_id": "TJAP1_MOUSE", "id": "Q9DCD5-1", "name": "Tight junction-associated protein 1", "aln": "----MSSAAPAKKPYRKAPPEHRELRLEIPVS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RLEQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EESLTDAERMKLLQQENEELRKRLASATRRTEALERELEIGQDCLELELGQSREELDKFKDKFRRLQNSYTASQRTNQELEDKLHALASLSHSWIFAIKKAEMDRKTLDWEIVELTN-KLLDARNTINKLEELNERYR-------------------------------LDCNLAVQLLKCNKSHFRNHKLADLPCELQDM------VRKHLRSGQ----EVASPSPSPSSSLSPGAVVPTSVIARVLEKPESLLLNSAQSGS--AGRPLAEDVFVHVDMSG------------GDPASPPAPGSP-----NGECCSVSTAGGSPEEELPLPAFDKLSPYPTPSPPHPLYPGRKVIEFS-EDKIR-------IPRNSPLPNCTYATRQAISLSLVEDGSERAHRS-SVPSSPASAQG-------------SPHHQPSP------------------APSALSAPASSASSEEDLLASWQRAFVDRTPPP--AAVVQRTAFGRDSLPELQLHFSPG---------------HSTAPPPSPHRERG-----------LVLPAEPDSGFPQDEEEEMLNLPVSPEEE------------------RQSLLPDKEGTEEASGPSHVDGRAWPLP-------------------SPSRPQRSPKRMGVHHLHRKDSLTQAQEQGTVLS-----------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5JTD0-1", "uniprot_id": "TJAP1_HUMAN", "id": "Q5JTD0-1", "name": "Tight junction-associated protein 1", "aln": "----MTSAAPAKKPYRKAPPEHRELRLEIPGS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RLEQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EEPLTDAERMKLLQEENEELRRRLASATRRTEALERELEIGQDCLELELGQSREELDKFKDKFRRLQNSYTASQRTNQELEDKLHTLASLSHSWIFAIKKAEMDRKTLDWEIVELTN-KLLDAKNTINKLEELNERYR-------------------------------LDCNLAVQLLKCNKSHFRNHKFADLPCELQDM------VRKHLHSGQ----EAASPGPAP--SLAPGAVVPTSVIARVLEKPESLLLNSAQSGS--AGRPLAEDVFVHVDMSEGVP---------GDPASPPAPGSPTPQ-PNGECHSLGTARGSPEEELPLPAFEKLNPYPTPSPPHPLYPGRRVIEFS-EDKVR-------IPRNSPLPNCTYATRQAISLSLVEEGSERARPS-PVPSTPASAQA-------------SPHHQPSP------------------APLTLSAPASSASSEEDLLVSWQRAFVDRTPPP--AAVAQRTAFGRDALPELQRHFAHSPAD-----------RDEVVQAPSARPEESE----------LLLPTEPDSGFPREEEE--LNLPISPEEE------------------RQSLLPINRGTEEGPGTSHTEGRAWPLP-------------------SSSRPQRSPKRMGVHHLHRKDSLTQAQEQGNLLN-----------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QNZ6-1", "uniprot_id": "A0A8M9QNZ6_DANRE", "id": "A0A8M9QNZ6-1", "name": "", "aln": "----MTSAAPARKPYRKAPPQHRETRHTVPVFREDVSGSALPSANPATSAQPDPCQVIFPRNHAPVLQRTRFTGPHPQSPERSSWSQASDSELEVSSLSSLELSVLPPPRIFSHSSLVMRLPPKHLRQQKMNRFISHSDDLLVFSADDDLASSSSSQQCIRGSSPSHSSRSAERSLVFKEKAEILVPREEKRPPLPASQMHVHPPKGILKQSHQLGVCLSDSLRKSKSAEMLDKAQSRGRSRKPKSMSLDREKGVRVSPMGHGTSTSSISPSSMLPDWKMQRLEEKVKFSQFVDEITYRVLSPANLKMLRGNLPRSTQTKQHNPQQYEFKDHHEKKQERCRPWDEWATQHSRTSRQSKEGRPKTWHIPGDSPERVPEKQHVDPHREGARPKAEGPIYSRVGGSDDSEWDDRTPLGDQLQVPHIENRTLQKDSVDKSGLPKGEIPTIRVESEKTSLSQVTAFTILSQIKESLSDADRIKILQQQNEDLRRRLSQTTHKMEAMETEFETSRHYMQAELGRTRDDLEKMRDKFRRLQNSYTASQRANQDLEEKLHALAAISQTWVYALRKVERDKKTMDQEIVELTN-KLVDAKNTIDKLEELNERYR-------------------------------QDCNLAVQLLKCNKSHFRNHKFADLPYELQDM------VNKHMKSSLPNKTQGAQAQDPDTLSLTPADVVPTSVIARVLEKPEPLVLNSAQSSSS-AGRPVAEDVFVHVDMTGPQDDDGGRENGGPVPARPPAVADTDQQHVNGMCRSQGSLDGPTGDDGAAPSFEKLNPYPTPSPPNPLYPGRKVIEFSSDDKVK-------IPKNSPLPNCTYATRQAISLSLVQNEEEAAERQRTVPNSPAISDGGWRSGTSSSSGGGIASHQRTPPQMDATDTLSSHSSPFSSPPQPPSAFASSGSSEEDLLASWQRMFVEKMAPSSDGSLVNRTSFSSETVKDLQRSHNGKSGVGALRGAYSDGEEGSSAQSWTASRESSLDTDTSSMADLRAKKTQYGGDFSHEEGEHLLMALDPLDNDGASGDTMVTIESSPASAKRQEFAEDVGSAGSSAEERDVLPQDFPVIGSRVL-SSLEDYADKPPRTGSSRPLKSPKRMGVHHLHRKDSLTRAQEHGNLLD-----------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VZP0-1", "uniprot_id": "Q9VZP0_DROME", "id": "Q9VZP0-1", "name": "Tight junction-associated protein 1", "aln": "MSTVVEQAATAGNPKAAEISTAKSAISTATAAPAIAATPLATSAPAAAEIEQLQQALIEKQTQLYALESACLRETERQVELEDSVIAWQDKYDRLYESHKRVQKVN----------------------------------------------------------------------------------------QSLEDKMLKLVDRNAGERAQLTSDVATLSVRLAQANFNIAKLQREIERYKADISLAIQLLQCKPDSFVSQKVSSLPIDIQSKVSAYMRLETNSHSDSECSNSGVGVATTASYKVLPASDSPPPSACPFPPTAMVYSMRGIGRYAANGNTTTNPQQQSNQPTNNN---------------------------------------------------------------------------------------------TSNNKDTLNNNNVNNNSNNNCNNQTNTSISNNNHATNPDMISPTIMAKFLEDELKANEVKHCDTCQCSKQDLQVLADVSRSYSVSTQTPHQLQLQGSGLNEPLTQLCLRCHSNLNSPSRTNSPYLMKMVKSSDSVISETKSSVSDLNDMDKLFIPAKKDDLMVNPILGHHRLCERTAISGQNTEYGNGKLTTSTMMYPTTHLGAYAAEKYLLETSNLGQLRNGYQRRFLDGGGTALQLLNKYEAGAVGVVHGDLEDESSKPLLAGVSQPSLLEAEQAPPQQSVVPAKLEDVCEPQPSKPVAPVAPP----GSTAPAVPSGTQLKSTNSGSVQSLWSNKTSSCEGAKMFETFNRNLIKTIKAENPKYRGPRLCAMRIQQNGQSNILLDNLESIETYTPVIYKRREKLLDEELNDGKDIITSK--ESNAQSVVEAWQGPAAPHENVALQPVLEPQVENAELEQVEIKPGDQAANPGVNSPKHSANSSSISDAIDYQESVLLRRQQLSRVAEWVQHNTQQLEQRNLQQAPPTSDSNSG---------TERQSSYSTLDRMDSISIEKLSMDSGYKTTPQQLTNGYPEKSTEDSLSPKTDITSN------------SLPENPSATIVPPKKTEMCTTYYRRTTRSGLPVAYTTIAGAPDDSSPPGESTSSGSEALICPEQPTCDILNYKYYPNDTDKTRSVQAELHTTTQNVDIAQMEYNVKQFLLKQNEWSMNGGASGAGPGAVLQGSGAARMLQRRILGPGVGERVRMATPGGAVATKSTGQSSNVLTPHRTETNL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .**.* :* . :. . *** .: : : :.::*. . : ..* : :* *:: .. ::::*: : * * . * :.:: : : . ..*: :. :.. . ... ::*: :: : :::.::..*::::: : : :*:.. : .:*: : . * .:: .::: .. : . . .: . : * . : .:. :*:: *: . : * : . . : : .* . . . .* * .. : : . * .. :* * * :: : ::: : : .. . * *: : . ::: : . ..: : . . : . . ::..** .* : : :: : . . .::.: : * . : : . :.... * * .: : . . *: . *.. .*:: . *: * . ::: .: ", "identical_positions": 45, "similar_positions": 204, "identity": "3.61%" }, { "cls_id": "homologset.agr.RGD:1308709", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4ABR9-1", "uniprot_id": "D4ABR9_RAT", "id": "D4ABR9-1", "name": "", "aln": "MVQLSLQVDDKGLWKGVHRPRKKSLTPAIFPCATSSHSSYCHTAPSPHLLQPLCLLRASLLSLRFYLLLPLLSSDLCSELQPFFLRSLVLPAHFHSAPAFPDASGMCTGKCARCLGLSLIPLSLICIVANALLLVPDGKTTWTDGN-LSLQVWLMGGFIGGGLMVLCPGIAAVRAGGKGCCGAGCCGNRCRMLRSVFSSAFGILGAIYCLSVAGAGLRVGPKCLINNKWDYHFQETQGGYLHNDTLWNLCEAPPHVVPWNVTLFSILVVASSLETVLCGIQLVNATLGVLCGDCRKKEGSAH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O14894-1", "uniprot_id": "T4S5_HUMAN", "id": "O14894-1", "name": "Transmembrane 4 L6 family member 5", "aln": "---------------------------------------------------------------------------------------------------------MCTGKCARCVGLSLITLCLVCIVANALLLVPNGETSWTNTNHLSLQVWLMGGFIGGGLMVLCPGIAAVRAGGKGCCGAGCCGNRCRMLRSVFSSAFGVLGAIYCLSVSGAGLRNGPRCLMNGEWGYHFEDTAGAYLLNRTLWDRCEAPPRVVPWNVTLFSLLVAASCLEIVLCGIQLVNATIGVFCGDCRKKQDTPH", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *********:*****.*.*:***********:*:*:**: * *******************************************************:*********:***** **:**:*.:*.***::* *.** * ***: *****:**********:**.**.** ***********:**:*******:.:.*", "identical_positions": 160, "similar_positions": 29, "identity": "52.98%" }, { "cls_id": "homologset.agr.RGD:1308710", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4AEK3-1", "uniprot_id": "D4AEK3_RAT", "id": "D4AEK3-1", "name": "Cysteine-rich motor neuron 1 protein", "aln": "MYLVAGGRGLAGCGHLSVSLLGLLLLLARSGTRALVCLPCDESKCEEPRSCPGSIVQGVCGCCYMCARQRNESCGGAYGLHGACDRGLRCVIRPPLNGDSITEYEVGVCEDEDWDDDQLLGFEPCNENLISGCNIINGRCECSTIRTCNNPFEFPRKDMCLSALKRIEEEKPDCTKARCEVQFSPRCPEDSILIEGYAPPGECCPLPSRCVCDPAGCLRKVCQPGYLNILVSKASGKPGECCDLYECKPVFSVDCSTVECPPVQQAVCPLDSYETQVRLTADGCCTLPARCECLSGLCAFPVCEVGSTPRIVSRGDGTPGKCCDVFECVNETKPACVFNSVEYYDGDMFRMDNCRFCRCQGGVSICFTAQCGELNCERYYVPEGECCPVCEDPIYPFNNPAGCYANGQIRAHGDRWREDDCTFCQCINGEPHCVATACGQSCMHPVKVPGECCPVCEEPTYITIDPPACGELSNCTLKEKDCVYGFKLDHNGCRTCQCKNREERCLALKRACTLDCPFGFLTDVHNCELCQCRPRPKKCRPTICDKFCPLGFLRNKHGCDICRCKKCPELPCSKVCPLGFQEDSHGCLICKCR-EVPTSAGPPVLSGTCLSMDGHHHKNEESWHDGCRECYCHNGKEMCALITCPVPACGNPTIRPGQCCPSCADDFVVQKPELSTPSICHAPGGEYFVEGETWNIDSCTQCTCHSGRVLCETEVCPPLLCQNPSRTQDSCCPQCTEDPLQPSTSHNESVPSYCRNDEGDIFLAAESWKPDVCTSCVCMDSSISCYSESCPSVACERPVLRKGQCCPYCLEDTIPKKVVCHFSGKTYADEERWDIDSCTHCYCLQGQTLCSTVSCPPLPCAEPIKVEGSCCPMCPEMYVPEPTNVPIEKKNHRGEIDLEVPMWPTPSENDIIHLPR-DMGHLQVDYRDNNRLHPSEDSSLDSIVPVVVPIIICLSIIIAFLLINQKKQWIPLLCWYRTPTKPSSLNNQLVSVDCKKGTRVQVDGSQRMLRIAEPDARFSGFYSMQKQNHLQADNFYQTV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JLL0-1", "uniprot_id": "CRIM1_MOUSE", "id": "Q9JLL0-1", "name": "Cysteine-rich motor neuron 1 protein", "aln": "MYLVAGGRGLAGCGHLSVSLLGLLLLLARSGTRALVCLPCDESKCEEPRSCPGSIVQGVCGCCYMCARQRNESCGGAYGLHGACDRGLRCVIRPPLNGDSITEYEVGVCEDEDWDDDQLIGFEPCNENLISGCNIINGKCECGTIRTCNNPFEFPRKDMCLSALKRIEEEKPDCSKARCEVRFSPRCPEDSILIEGYAPPGECCPLPSRCVCDPAGCLRKVCQPGYLNILVSKASGKPGECCDLYECKPVFSVDCSTVECPPVQQAVCPLDSYETQVRLTADGCCTLPARCECLSGLCGFPVCEVGSTPRIVSRGDGTPGKCCDVFECVNETKPACVFNSVEYYDGDMFRMDNCRFCRCQGGVSICFTAQCGELNCERYYVPEGECCPVCEDPIYPLNNPAGCYANGQIRAHGDRWREDDCTFCQCINGEPHCVATACGQSCMHPVKVPGECCPVCEEPTYITIDPPACGELSNCSLKEKDCVYGFKLDHNGCRTCQCKIREELCLGLKRACTLDCPFGFLTDVHNCELCQCRPRPKKCRPTMCDKFCPLGFLKNKHGCDICRCKKCPELPCSKICPLGFQQDSHGCLICKCR-EVPPSAGPPVLSGTCLSMDGHHHKNEESWHDGCRECYCHNGKEMCALITCPVPACGNPTIRSGQCCPSCTDDFVVQKPELSTPSICHAPGGEYFVEGETWNIDSCTQCTCHSGRVLCETEVCPPLLCQNPSRTQDSCCPQCTDDPPQPSTSHNESVPSYCRNDEGDIFLAAESWKPDACTSCVCVDSAISCYSESCPSVACERPVLRKGQCCPYCLEDTIPKKVVCHFSGKTYADEERWDIDSCTHCYCLQGQTLCSTVSCPPLPCAEPIKVEGSCCPMCPEMYVPEPTNVPIEKKNHRGEIDLEVPMWPTPSENDIIHLPR-DMGHLQVDYRDNNRLHPGEDSSLDSIVSVVVPIIICLSIIIAFLLINQKKQWVPLLCWYRTPTKPSSLNNQLVSVDCKKGTRVQVDGPQRMLRIAEPDARFSGFYSMQKQNHLQADNFYQTV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NZV1-1", "uniprot_id": "CRIM1_HUMAN", "id": "Q9NZV1-1", "name": "Cysteine-rich motor neuron 1 protein", "aln": "MYLVAGDRGLAGCGHLLVSLLGLLLLLARSGTRALVCLPCDESKCEEPRNCPGSIVQGVCGCCYTCASQRNESCGGTFGIYGTCDRGLRCVIRPPLNGDSLTEYEAGVCEDENWTDDQLLGFKPCNENLIAGCNIINGKCECNTIRTCSNPFEFPSQDMCLSALKRIEEEKPDCSKARCEVQFSPRCPEDSVLIEGYAPPGECCPLPSRCVCNPAGCLRKVCQPGNLNILVSKASGKPGECCDLYECKPVFGVDCRTVECPPVQQTACPPDSYETQVRLTADGCCTLPTRCECLSGLCGFPVCEVGSTPRIVSRGDGTPGKCCDVFECVNDTKPACVFNNVEYYDGDMFRMDNCRFCRCQGGVAICFTAQCGEINCERYYVPEGECCPVCEDPVYPFNNPAGCYANGLILAHGDRWREDDCTFCQCVNGERHCVATVCGQTCTNPVKVPGECCPVCEEPTIITVDPPACGELSNCTLTGKDCINGFKRDHNGCRTCQCINTEELCSERKQGCTLNCPFGFLTDAQNCEICECRPRPKKCRPIICDKYCPLGLLKNKHGCDICRCKKCPELSCSKICPLGFQQDSHGCLICKCR-EASASAGPPILSGTCLTVDGHHHKNEESWHDGCRECYCLNGREMCALITCPVPACGNPTIHPGQCCPSCADDFVVQKPELSTPSICHAPGGEYFVEGETWNIDSCTQCTCHSGRVLCETEVCPPLLCQNPSRTQDSCCPQCTDQPFRPSLSRNNSVPNYCKNDEGDIFLAAESWKPDVCTSCICIDSVISCFSESCPSVSCERPVLRKGQCCPYCIEDTIPKKVVCHFSGKAYADEERWDLDSCTHCYCLQGQTLCSTVSCPPLPCVEPINVEGSCCPMCPEMYVPEPTNIPIEKTNHRGEVDLEVPLWPTPSENDIVHLPR-DMGHLQVDYRDN-RLHPSEDSSLDSIASVVVPIIICLSIIIAFLFINQKKQWIPLLCWYRTPTKPSSLNNQLVSVDCKKGTRVQVDSSQRMLRIAEPDARFSGFYSMQKQNHLQADNFYQTV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7T3Q2-1", "uniprot_id": "CRIM1_DANRE", "id": "Q7T3Q2-1", "name": "Cysteine-rich motor neuron 1 protein", "aln": "---MASSRMYLLVKCMLI--LQLMVLIAKN-SRALICLPCDKSKCEEPKPCTGSVVLGICGCCSVCAKQKNESCGGVYGLYGTCDRGLRCVIRPPLNGGSITQYEVGNCEDENWDDDQLLGFEPCNENLVTGCNIIDGKCECDSVRTCNNPFEFASQEACQTALQKIEEERPDCSKARCEVQFSPRCPEDSILIEGYAPPGECCPLPSRCVCSPAGCLRKVCQPGHLNILVSKSSGKPGECCDLYECKPVFSVDCSTVECPPVKPVQCPADSYETQVRLTADGCCTLPTRCECLPGLCTFPQCSAGMSPQVMSRGDGTPGRCCDVFECVNETKPACTLNGVEYHDGDMFRMDACRFCRCQGGVSVCFTAQCGVLHCERYYVPDGECCPVCEDPIYPVLSLAGCYVNGQILAHGDHWREDDCTFCQCVSGDARCVAAACGHSCLNPVTVPGECCPVCEEPTYITMAPPACGSLDNCTLLEQSCAFGFRLDPSGCRTCACKSREELCGGLMASCTLKCPFGFQTDIHGCDVCQCRPRHKKCKAVACAKDCPFGYIKNKHGCDTCRCKKCPELPCDKACPMGFQHDELGCLICQCRDQSSSSVTPAVKLGSCLSMDGRRHENGQSWHDGCRDCYCHAGREMCALISCPVPPCDNPTIRPGHCCPTCPEESSSHKPELSEASVCLAPGGEYFVEGETWNIDSCTQCTCHSGRVLCETEVCPPLLCHSPIRTQDSCCPHCPDDPVTPQTPSNDSMPSYCRNEDGDIFLAAESWKPNVCSSCVCLDGAISCFSESCPPVNCARPVLRKGQCCPYCLDATP--RAVCHFNGKTYMDEERWDIDSCTHCYCLQGQTLCSTVSCPALPCHQPLTVEGSCCPMCPESYA--PTNVPIEKTDQRGDKSRHQPAWPTHSENDVMPQFRGEFGSLQMPYLDGKTPLPSEDAGLH-WAWVALPVLMMMLTLAALLLVNQRKQWIPVPC-YRTPNKSTCLNNQLVYVDCQKGTKVQVDSSQRMLRIADPDSRYSGYYSMQKHNNLQADNFYQTA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*..* : : * *::*:*:. :***:*****:******: *.**:* *:**** ** *:******.:*::*:***************.*:*:**.* ****:* ****:**:******::*****:*:***.::***.*****. :: * :**::****:***:******:*********:********************.************ *******:*****************.*** *******: . ** ******************:*****.*** ** *..* :*:::********:*********:*****.:*.***:******** **********::******* ::*******:**********:**. . ****.** * ****:***********:.*: :***:.**::* :**.************* **: *****.*.**:* :.* **: * .***** * ** * .***.***** ** :.*::*:**** ***:. * * **:* ::****** *********.*.* **:***.*. *****:** : ..*. *.: *:**::**::*:* :*******:*** *:******:****.*.****:.*:***:*.:: :***** .*:* ****************************************:.* ********:*.::* *. . *:*:*.**:*::************:.*:**:*:*. ***:*****.* * *************:: * :.****.**:* ******:*********************.*** :*:.*********** *. ***:****.::**: . . * *** ****:: * ::* **: * *. *.**:.*. . *.:*::: : : *:*::**:***:*: * ****.*.:.****** ***:***:****..*******:**:*:**:*****:*:*********.", "identical_positions": 692, "similar_positions": 221, "identity": "66.6%" }, { "cls_id": "homologset.agr.RGD:1308711", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4AA20-1", "uniprot_id": "D4AA20_RAT", "id": "D4AA20-1", "name": "Zinc finger protein 697", "aln": "MSFVQPHRKPQREGSGQPARVPARGPIAAASGRRAGARLGQCAQESPGASQGPCFPPCSLSCWMEQEDNLGVCADQSSEDRGMGSDFENSEDQEGDPEERGVGSNPQDTEER-GHLEQELDSNPQDDDLRGDPPERDIVSTVCSEGLLSEEEGAILREEEDDQPGVADMALFPGLSESDSITRSPQGEEEEEEE-EEEESAGENRLIEKEEPLPTPVLPWRRHLSLGGRHRGDKPAYRRFHRLHHPMAVDLGELDSLMASIMDAPTICPDCGESFSPGAAFLQHQRIHRLAEAAAMASLEPFGLAGECGGVVGMMG----VGMGVSGGFGAGPTLARPPREKPFRCGECGKGFSRNTYLTNHLRLHTGERPNLCADCGKSFSWRADLLKHRRLHTGEKPYPCPECGEAFSLSSHLLSHRRAHAAAGGAGSAAAAAAALRPFACGECGKGFVRRSHLANHQRIHTGEKPHGCGECGKRFSWRSDLVKHQRVHTGEKPYMCSECGETFSVSSHLFTHKR-THSGERPYVCRECGKGFGRNSHLVNHLRVHTGEKPFSCGQCEKRFSDFSTLTQHQRTHTGEKPYTCLECGKSFIQSSHLIRHRRIHTGNKPHKCTGCGKGFRYKTHLAQHQKLHLC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q569E7-1", "uniprot_id": "ZN697_MOUSE", "id": "Q569E7-1", "name": "Zinc finger protein 697", "aln": "---------------------------------------------------------------MEQEDNQGVCEYQTSEDRGMDSDLENSEDREGDPEERGMGSNPWDTEDR-GHLEQEVDSNPQDDDLRGDSRERDRASTVCSEGRLSEEERAILREEEDDQPGVADMALFPGLSESDSISRSPRGEEDEEEEDEEEESAGENRLIEEEDPLPTPVLPWRRHLSLGGRHRGDKPAHRRFHRLHHPMAMDLGELDSLMASIMDAPTICPDCGESFSPGAAFLQHQRIHRLAEAAAVASLEPFGLAGECGGVVGMMGMGMGVGMGVAGGFGAGPTLARPPREKPFRCGECGKGFSRNTYLTNHLRLHTGERPNLCADCGKSFSWRADLLKHRRLHTGEKPYPCPECGEAFSLSSHLLSHRRAHAAAGGGAGSAGSAAALRPFACGECGKGFVRRSHLANHQRIHTGEKPHGCGECGKRFSWRSDLVKHQRVHTGEKPYMCSECGETFSVSSHLFTHKR-THSGERPYVCRECGKGFGRNSHLVNHLRVHTGEKPFGCGQCEKRFSDFSTLTQHQRTHTGEKPYTCLECGKSFIQSSHLIRHRRIHTGNKPHKCAGCGKGFRYKTHLAQHQKLHLC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5TEC3-1", "uniprot_id": "ZN697_HUMAN", "id": "Q5TEC3-1", "name": "Zinc finger protein 697", "aln": "---------------------------------------------------------------MKQEDNQGVCAHQDSEDKGMGSDFEDSEDREGDPEEREMGSNPHDTNKREGHPEPEMGSNPQD------SRHREAVPDICTEGQLSEEEGVSVRGEEDDQSGVADMAMFPGLSESDSISRSLREDDD--------ESAGENRLEEEEEQPAPPVLPWRRHLSLGSRHRGDKPAHRRFHRLHHPMAVDLGELDSLVASIMDAPTICPDCGESFSPGAAFLQHQRIHRLAEAAAAASLEPFGLAGECDAMVGMMG------VGVAGGFGAGPPLARPPREKPFRCGECGKGFSRNTYLTNHLRLHTGERPNLCADCGKSFSWRADLLKHRRLHTGEKPYPCPECGEAFSLSSHLLSHRRAHAAASGAG-----AAALRPFACGECGKGFVRRSHLANHQRIHTGEKPHGCGECGKRFSWRSDLVKHQRVHTGEKPYMCSECGETFSVSSHLFTHKR-THSGERPYVCRECGKGFGRNSHLVNHLRVHTGEKPFRCGQCEKRFSDFSTLTQHQRTHTGEKPYTCIECGKSFIQSSHLIRHRRIHTGNKPHKCAGCGKGFRYKTHLAQHQKLHLC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B621-1", "uniprot_id": "A0ACD6B621_DANRE", "id": "A0ACD6B621-1", "name": "", "aln": "---------------------------------------------------------------------------------------------MSDPEPCRIKQE-----------------------------EAEELIDLIEENEESKEIKPHVKAET-----------LPQLQTFDTY------------------------FIKEEE-------------SQECKNG----------------------------------CVCTQCGKRFRLSSALEKHMRIH--------------------------------------------------TGEKPFTCTQCGKSFGRLSHLNKHMRIHTGERPFTCTQCGKSFTRSYYLNLHMMIHTGE-----------------------------------------RPHNCDQCGKTFMRSSQLKMHLRVHTKEKPYSCSECGKSFTQQSNLRKHQKIHTGLKEHMCLECQQTFVTAGQLKQHQR-IHTGEKPYTCSHCKKRFNQSGSLKTHQMIHTGEKPYKCSHCNKRFSQSGSMKAHERIHTGEKPYTCDQCLKSFTHLFQRNKHMKIHKGEKQHT-----------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3AUK5-1", "uniprot_id": "A0A8M3AUK5_DANRE", "id": "A0A8M3AUK5-1", "name": "", "aln": "---------------------------------------------------------------------------------------------MSDPKPCKIKQE-----------------------------ETDDRQNMNDPEPCG---------------------------------------------------------IKQEE------------------------------------------------------------------TDDREHMN--------------------------------------------------------DPETCGIKQEETEDTENMSDPE---------------------------------------------------------------------------------------LKEEETEEQTDLNESEE--------SEYDERKDLKKRRRKK-------CLTCSQTFVTAGQLKRHQV-IHAGETKYTCSHCGKAFTQVQNLKRHERIHTGEKPYKCSHCDKSFTQLPNLKCHERIHTGEKPYRCQQCLKRFTQLSQLQKHTNMHR-KAGHVI----------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VHR4-1", "uniprot_id": "Q9VHR4_DROME", "id": "Q9VHR4-1", "name": "", "aln": "---------------------------------------------------------------MSPPSGEFRCRVCLKQDELLVDIYEIVEEMQVDLCTLLETCG-------------------------GIKVDRRDVQPMYLCQECTNELLIAAKFRKICVESEKLRDMAPEIN------------------------------IDTAEP------------------------------------------------------LASEEIIIIDPSDYIEQLSAVED--------------------------------------------PENEPIGVSRWNCQHCGAGFQLSEVLRRHIQEVHASITIIDCRERRRIFTKLGCYQVHNCSYAKTPK--------------------------------------RGHKCLECGKCLQSASSLASHIRLHTDEWPFTCDQCAKAFRTNGALEVHQRRHKQVLQHKCLHCGRGFVESSNLRRHIVNRHTEERPHLCNVYQRSFSRVYMLELHLRTNTGERPYACQHRDKRFAQLGVLKIHERIHTGERLHRCQVCEKPFTRAGQLRKHALRHETGQ--------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . : . : : . * : . : :: * . : . * ::: : * * . * :.:* * *: * : * : * : * * :***:*: * : :* *:: :. *:* ****: : * * * * : : :* * ", "identical_positions": 34, "similar_positions": 41, "identity": "5.36%" }, { "cls_id": "homologset.agr.RGD:1308712", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZII9-1", "uniprot_id": "D3ZII9_RAT", "id": "D3ZII9-1", "name": "Guanylyl cyclase-activating protein 1", "aln": "MGNVVEGKSVEELSSTECHQWYKKFMTECPSGQLTLYEFRQFFGLKNLSPSASQYVEQMFETFDFNKDGYIDFMEYVAALSLVLKGKVEQKLRWYFKLYDVDGNGCIDRDELLTIIRAIRTINPWSDSSMSAEEFTDTVFAKIDINGDGELSLEEFMEGVQKDQMLLDTLTRSLDLTRIVRRLQNGEQEEAGAGDLAAEAAG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P43081-1", "uniprot_id": "GUC1A_MOUSE", "id": "P43081-1", "name": "Guanylyl cyclase-activating protein 1", "aln": "MGNIMEGKSVEELSSTECHQWYKKFMTECPSGQLTLYEFRQFFGLKNLSPSASQYVEQMFETFDFNKDGYIDFMEYVAALSLVLKGKVEQKLRWYFKLYDVDGNGCIDRDELLTIIRAIRTINPWSDSSMSAEEFTDTVFAKIDINGDGELSLEEFMEGVQKDQMLLDTLTRSLDLTGIVRRLQNGEHEEAGTGDLAAEAAG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P43080-1", "uniprot_id": "GUC1A_HUMAN", "id": "P43080-1", "name": "Guanylyl cyclase-activating protein 1", "aln": "MGNVMEGKSVEELSSTECHQWYKKFMTECPSGQLTLYEFRQFFGLKNLSPSASQYVEQMFETFDFNKDGYIDFMEYVAALSLVLKGKVEQKLRWYFKLYDVDGNGCIDRDELLTIIQAIRAINPCSDTTMTAEEFTDTVFSKIDVNGDGELSLEEFIEGVQKDQMLLDTLTRSLDLTRIVRRLQNGEQDEEGA-DEAAEAAG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RRU8-1", "uniprot_id": "A0A8M1RRU8_DANRE", "id": "A0A8M1RRU8-1", "name": "Guanylyl cyclase-activating protein 1", "aln": "MGNAP-GTSVEELSACESHQWYRKFMTECPSGQLTFYEFKKFFGLKNLSEKSNEYVMTMFQTFDMNDDGCIDFMEYVAALSLILKGGVQQKLRWYFKLYDVDGSGCIDREELLLIVKAIRAIN-GVEQEVSAEEFTNMVFEKIDLNADGVLTMDEFMEGIQADEYLSTMLTQSLDLTHIVKKIYSEIHCEQEPH--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8N7UZP3-1", "uniprot_id": "A0A8N7UZP3_DANRE", "id": "A0A8N7UZP3-1", "name": "", "aln": "MGNST-GSTVDDLQAVEMHLWYKKFMTECPSGQLTLHEFKQFFGLRGLDPEANAYIEQMFRTFDMNKDGYIDFMEYVAALSLVMRGKMEHKLRWYFRLYDVDGNGCIDRYELLNIIKAIRAINGSETQESSAEEFTNRVFERIDINGDGELSLDEFVAGARSDEEFMEVMMKSLDLTHIVAMIHNRRHSV------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** *.:*::*.: * * **:************::**::****:.*. .:. *: **.***:*.** ************:::* :::******:******.***** *** *::***:** :*****: ** :**:*.** *:::**: * : *: : : :***** ** : . : ", "identical_positions": 101, "similar_positions": 49, "identity": "50.0%" }, { "cls_id": "homologset.agr.RGD:1308713", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "B1WCA1-1", "uniprot_id": "B1WCA1_RAT", "id": "B1WCA1-1", "name": "Fizzy-related protein homolog", "aln": "--------MDQDYERRLLRQIIIQNENTVPCVSEMRRTLTPANSPVSSP-SKHGDRFIPSRAGANWS--VNFHRINE-NEKSPSQNRKAKDATSDNGKDGLAYSALLKNELLG-----------AGIEKVQDPQTEDR----------------RLQPSTPEHKGLFTYS-----LSSKRSSPDDGNDVSP---------------------------------YSLSPVSNKSQKLLRSPRKPTRKISKIPFKVLDAPELQDDFYLNLVDWSSLNVLSVGLGTCVYLWSACTSQVTRLCDLSVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSVLEGHTARVGALAWNADQLSSGSRDRMILQRDIRTPALQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKPCPALQLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRSTK---ESVSVLNLFTRIR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R1K5-1", "uniprot_id": "FZR1_MOUSE", "id": "Q9R1K5-1", "name": "Fizzy-related protein homolog", "aln": "--------MDQDYERRLLRQIIIQNENTVPCVSEMRRTLTPANSPVSSP-SKHGDRFIPSRAGANWS--VNFHRINE-NEKSPSQNRKAKDATSDNGKDGLAYSALLKNELLG-----------AGIEKVQDPQTEDR----------------RLQPSTPEHKGLFTYS-----LSSKRSSPDDGNDVSP---------------------------------YSLSPVSNKSQKLLRSPRKPTRKISKIPFKVLDAPELQDDFYLNLVDWSSLNVLSVGLGTCVYLWSACTSQVTRLCDLSVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNADQLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNK------LLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRSTK---ESVSVLNLFTRIR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UM11-1", "uniprot_id": "FZR1_HUMAN", "id": "Q9UM11-1", "name": "Fizzy-related protein homolog", "aln": "--------MDQDYERRLLRQIVIQNENTMPRVTEMRRTLTPASSPVSSP-SKHGDRFIPSRAGANWS--VNFHRINE-NEKSPSQNRKAKDATSDNGKDGLAYSALLKNELLG-----------AGIEKVQDPQTEDR----------------RLQPSTPEKKGLFTYS-----LSTKRSSPDDGNDVSP---------------------------------YSLSPVSNKSQKLLRSPRKPTRKISKIPFKVLDAPELQDDFYLNLVDWSSLNVLSVGLGTCVYLWSACTSQVTRLCDLSVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAEQLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNK------LLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRSTKVKWESVSVLNLFTRIR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RLN6-1", "uniprot_id": "A0A8M1RLN6_DANRE", "id": "A0A8M1RLN6-1", "name": "Fizzy-related protein homolog", "aln": "--------MDQDYERRLLRQINHQN---VPEGHPTKQSNYAACSPVS---VKSGDRFIPTRAGSNWS--INFHYANE-NCWSPNQNQRAKDASTDTGKDAVAYAALLRNELLG-----------AGIETVPDPHTDDR----------------RHTILTQDTHSLFRYT-----IHTKRVPFD--NEISP---------------------------------YSLSPLSNKSHKLLRSPRKPARKISKIPFKVLDAPELQDDFYLNLVDWSAGNLLSVGLGACVYLWSACTSQVTRLCDLSVDGDSVTSVCWNERGSLVAVGTHKGFVQIWDAAGGRKLTSLEGHSARVGALAWNGEQLSSGSRDRVILQRDVRTPPP-VERRLQGHRQEVCGLKWSPDHQHLASGGNDNK------LLVWNSSSLLPVQQYSDHLAAVKAIAWSPHQHGLLASGGGTADRCLRFWNTLTGQALQSTDTGSQVCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAVSPDGEAIVTGAGDETLRFWNVFSKTRCTK---ESKSVLNLFTRIR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W4H9-1", "uniprot_id": "Q9W4H9_DROME", "id": "Q9W4H9-1", "name": "Fizzy-related protein homolog", "aln": "-------MFSPEYEKRILKHY-------SPVARNLFNNFESSTTPTS------LDRFIPCRAYNNWQ--TNFASINKSNDNSPQTSKKQRDCG-ETARDSLAYSCLLKNELLG-----------SAIDDVKTAGEERN----------------ENAYTPAAKRSLFKYQ-----SPTKQ----DYNGECP---------------------------------YSLSPVSAKSQKLLRSPRKATRKISRIPFKVLDAPELQDDFYLNLVDWSSQNVLAVGLGSCVYLWSACTSQVTRLCDLSPDANTVTSVSWNERGNTVAVGTHHGYVTVWDVAANKQINKLNGHSARVGALAWNSDILSSGSRDRWIIQRDTRTPQLQSERRLAGHRQEVCGLKWSPDNQYLASGGNDNR------LYVWNQHSVNPVQSYTEHMAAVKAIAWSPHHHGLLASGGGTADRCIRFWNTLTGQPMQCVDTGSQVCNLAWSKHSSELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLALSPDGEAIVTGAGDETLRFWNVFSKARSQK---ENKSVLNLFANIR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53197-1", "uniprot_id": "CDH1_YEAST", "id": "P53197-1", "name": "APC/C activator protein CDH1", "aln": "MSTNLNPFMNNTPSSSPLKGSESKRVSKRPISSSSSASLLSSPSRRSRPSTVYGDRYIPSRTDIDFNSIVSISSMASVPALNPSSTEDQVEYQKERQAH-ETYNTLLKNELFGEMLSKDTVGSESSIDRIKNTRPSTRGNVHAENTTRHGYELERVSTPPPEAAGLEEFSPHSTPVTPRRLFTSQQDEITRPSSNSVRGASLLTYQQRKGRRLSAASLLQSQFFDSMSPVRPDSKQLLLSPGKQFRQIAKVPYRVLDAPSLADDFYYSLIDWSSTDVLAVALGKSIFLTDNNTGDVVHLCDT---ENEYTSLSWIGAGSHLAVGQANGLVEIYDVMKRKCIRTLSGHIDRVACLSWNNHVLTSGSRDHRILHRDVRMPDPFFET-IESHTQEVCGLKWNVADNKLASGGNDNV------VHVYEGTSKSPILTFDEHKAAVKAMAWSPHKRGVLATGGGTADRRLKIWNVNTSIKMSDIDSGSQICNMVWSKNTNELVTSHGYSKYNLTLWDCNSMDPIAILKGHSFRVLHLTLSNDGTTVVSGAGDETLRYWKLFDKPKAKVQ--PNSLIFDAFNQIR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . *: * . .: : * **:** *: ::. .: . .*. .. : : . :* **:***:* :.*: : . . . . . .* : .:: : *:**: .*::** ** * *:*:::*::*****.* **** .*:***: ::*:*.** .::* . *.:*.:*** : **: * *. :*** :* * ::*. : : *.** **..*:** . *:*****: *::** * * * : .* ********. .: ******** : *:: * *: : :* *****:*****::*:**:******* :::**. *. :. *:***:**:.***::.***::****: :: :*. *: :* *.***:***:*::* ** ::*:********:*::*.*.:. . ::: * .**", "identical_positions": 173, "similar_positions": 146, "identity": "29.88%" }, { "cls_id": "homologset.agr.RGD:1308714", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "F1LY63-1", "uniprot_id": "F1LY63_RAT", "id": "F1LY63-1", "name": "RING-type E3 ubiquitin transferase", "aln": "MSESGEMSEFGYIMELLAKGKVTIKNIEKELICPACKELFTHPLILPCQHSVCHKCVKELLLS-LDDSFN-DVASDSSNQSSPRLRLTSPSMDKIDK---INRPGWKRNSLTPRPTMFPCPGCEHDVDLGERGVSGLFRNFTLETIVERYRQAARAATAIMCDLCKPPPQESTKSCMDCSASYCNECFKIYHPWGTVKAQHEYVGPTTNFRPKILMCPEHETERINMYCELCRRPVCHLCKLGGNHSNHRVTTMSSAYKTLKEKLSKDIDFLIGKESQVKSQISELNLLMKETECNGERAKEEALAHFEKLFEILEDRKSSVLKAIDASKKLRLDKFHTQMEEYQGLLENNGLVGYAQEVLKETDQSCFVQTAKQLHLRIQKATESLKSFRPAAQASFEDYVVNISKQTEVLGELSFFSSGIDIPEINEEQSKVYNNALIDWHHPEKDK-ADSYVLEYRKINRDE-------EMISWNEIEVHGTSKVVSNLESNSPYAFRVRAYRGSICSPCSRELVLHTPPAPVFSFLFDEKCGYNTEHLLLNLKRDRVESRAGFNVLLAAERIQVGHYTSLDYIIGDVGITKGKHFWACRVEPYSYLVKVGVASSDKLQEWLRSPRDAASPRYEQDSGHDSGSEDAYFDSSQPFTLVTIGMKKFFIPKSPTSSNEPENRVLPMPTSIGIFLDCDKGKVSFYDMDHMKCLYERQVDCSHTMYPAFALMGSGG----IQLEETITAKYLEYEEDV-------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80WG7-1", "uniprot_id": "TRI36_MOUSE", "id": "Q80WG7-1", "name": "E3 ubiquitin-protein ligase Trim36", "aln": "MSESEEISEFGYIMELLAKGKVTIKNIEKELICPACKELFTHPLILPCQHSVCHKCVKELLLS-LDDSFN-DVASDSSNQSSPRLRLTSPSMDKIDK---INRPGWKRNSLTPRPTTFPCPGCEHDVDLGERGVSGLFRNFTLETIVERYRQAARAATAIMCDLCKPPPQESTKSCMDCSASYCNECFKIYHPWGTVKAQHEYVGPTTNFRPKVLMCPEHETERINMYCELCRRPVCHLCKLGGNHSNHRVTTMSSAYKTLKEKLSKDIDFLIGKESQVKSQISELNLLMKETECNGERAKEEALAHFEKLFEILEDRKSSVLKAIDASKKLRLDKFHTQMEEYQGLLENNGLVGYAQEVLKETDQSCFVQTAKQLHLRIQKATESLKSFRPAAQASFEDYVVNISKQTEVLGELSFFSSGIDIPEINEEQSKVYNNALIDWHHPEKDK-ADSYVLEYRKINRDE-------EMISWNEIEVHGTSKVVSNLESNSPYAFRVRAYRGSICSPCSRELILHTPPAPVFSFLFDEKCGYNTEHLLLNLKRDRVESRAGFNVLLAAERIQVGHYTSLDYIIGDVGVTKGKHFWACRVEPYSYLVKVGVASSDKLQEWLRSPRDAASPRYEQDSGHDSGSEDACFDSSQPFTLVTIGMKKFFIPKSPTSSNEPENRVLPMPTSIGIFLDCDKGKVSFYDMDHMKCLYERQVDCSHTMYPAFALMGSGG----IQLEEAITAKYLEYEEDV-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NQ86-1", "uniprot_id": "TRI36_HUMAN", "id": "Q9NQ86-1", "name": "E3 ubiquitin-protein ligase TRIM36", "aln": "MSESGEMSEFGYIMELIAKGKVTIKNIERELICPACKELFTHPLILPCQHSICHKCVKELLLT-LDDSFN-DVGSDNSNQSSPRLRLPSPSMDKIDR---INRPGWKRNSLTPRTTVFPCPGCEHDVDLGERGINGLFRNFTLETIVERYRQAARAATAIMCDLCKPPPQESTKSCMDCSASYCNECFKIHHPWGTIKAQHEYVGPTTNFRPKILMCPEHETERINMYCELCRRPVCHLCKLGGNHANHRVTTMSSAYKTLKEKLSKDIDYLIGKESQVKSQISELNLLMKETECNGERAKEEAITHFEKLFEVLEERKSSVLKAIDSSKKLRLDKFQTQMEEYQGLLENNGLVGYAQEVLKETDQSCFVQTAKQLHLRIQKATESLKSFRPAAQTSFEDYVVNTSKQTELLGELSFFSSGIDVPEINEEQSKVYNNALINWHHPEKDK-ADSYVLEYRKINRDD-------EMS-WNEIEVCGTSKIIQDLENSSTYAFRVRAYKGSICSPCSRELILHTPPAPVFSFLFDEKCGYNNEHLLLNLKRDRVESRAGFNLLLAAERIQVGYYTSLDYIIGDTGITKGKHFWAFRVEPYSYLVKVGVASSDKLQEWLRSPRDAVSPRYEQDSGHDSGSEDACFDSSQPFTLVTIGMQKFFIPKSPTSSNEPENRVLPMPTSIGIFLDCDKGKVDFYDMDQMKCLYERQVDCSHTLYPAFALMGSGG----IQLEEPITAKYLEYQEDM-------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A9A8-1", "uniprot_id": "A0AB13A9A8_DANRE", "id": "A0AB13A9A8-1", "name": "", "aln": "MSDS-EMSEFASLVERLDRGEVPMKSIERELICPICKELFTHPLILPCQHSICHRCVKELLFPNHEDSFSTDAGSESSNPGSPRSRVPSPGLDKLVRSGSICSPGWRRSSVTPRVTSFPCPGCQHDIDLGERGISMLFRNFTLESIVERYRQAARAAVAIMCGVCKPPPQEATKSCMDCKASFCNECFKLHHPWGTPRAQHEYVGPTTNFRPKVLMCPEHEMEKVNMYCEVCRRPVCHLCKLGGSHANHRVTSMSSAYKILKEKLSKSIHYLISKEEQVRTQITALELLMRSTEENGQLAERRANEHFERLQVALQERRAEMLWAVQQCRSRRVERLRAQVEEYQGMLENSGLVGYAQEVLKETDQSCFVQTAKLLHVRIQKATDSLKTFQPAASSSFEEFQLDTSREEILLKELSFGG-VPDAPVLDLSRCRVYNEALLHWRLPEDSVPTDRHLLEFRKLQQDEEEEKEEVERCWRTSESVYGSSTVVCDLDRDARYAFRVKSCRNGVCSAYSPEVTLHTPPAPVFSFLFSDSCGFSAERLQLSRRRASVESVAGMSVLLAAERVQTGSYTCLDYIIGDTGISQGRHYWAFRVDPASYLVKVGVASDCKLADWFHGPRDSSSPRFDQDSGHDSGSEDVCVDVCQPFLLLTVGMGRLFVPKPP----APESRVLPLPARIGVCLDYEAGRVSFYDGDSLRCPCVRPVECSGEHVSSIRPDGGAEPYTWRSQSQPSGSHTCEEESDCVCVCVCACACACVSVRASQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:* *:***. ::* : :*:*.:*.**:***** ****************:**:******:. :***. *..*:.** .*** *:.**.:**: : * ***:*.*:*** * ******:**:******:. ********:************.****.:*******:*******.**:******::***** :***************:******* *::*****:*************.*:*****:****** *******.*.:**.**.**::**: *:***:.** **: *:..* ***:* *::*::.:* *:: .:. *::::::*:*****:***.*********************** **:******:***:*:***.:***:: :: *:: :* **** . * * :: .:.:***:**:.*: **.. :* ::**:**:::*: * .. .* *:*.:: :*: .: *****:: :..:**. * *: *************.:.**:. *:* *. :* *** **:.:******:*.* **.*******.*:::*:*:** **:* **********. ** :*::.***: ***::***********. .* .*** *:*:** ::*:**.* **.****:*: **: ** : *:*.*** * ::* * *:** .:: *.. . .:. :: * :.* ", "identical_positions": 422, "similar_positions": 203, "identity": "55.16%" }, { "cls_id": "homologset.agr.RGD:1308715", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LAL4-1", "uniprot_id": "A0ABK0LAL4_RAT", "id": "A0ABK0LAL4-1", "name": "Importin-5", "aln": "MCSVLPGLSLYIQVYFPCVIQFYSSEPAAERRADSDSREGRSQLHSSVSMVTSLSCEVRTVGLVPSYDRSKHRAENSLDYCGSGEKPCQGPCVSTATFLDRDLCVTSRERKFLSKEHRSESVVPCLQIPENQVEKLGATENTVRAMAAAAAEQQQFYLLLGNLLSPDNVVRKQAEETYENIPGRSK----ITFLLQAIRNTTAAEEARQMAAVLLRRLLSSAFDEVYPALPSDVQTAIKSELLMIIQMETQSSMRKKICDIAAELARNLIDEDGNN---QWPEGLKFLFDSVSSQNMGLREAALHIFWNFPGIFGNQQQHYLDVIKRMLVQCMQDQEHPSIRTLSARATAAFILAN--EHNVALFKHFADLLPGFLQAVNDSCYQNDD-SVLKSLVEIADTVPKYLRPHLEATLQLSLKLCGDTNLNNMQRQLALEVIVTLSETAAAMLRKHTN----IIAQTIPQMLAMMVDLEEDEDWANADELEDDDFDSNAVAGESALDRMACGLGGKLVLPMIKEHIMQMLQNADWKYRHAGLMALSAIGEGCHQQMEGILNEIVNFVLLFLQDPHPRVRYAACNAVGQMATDFAPGFQKKFHEKVIAALLQTMEDQGNQRVQAHAAAALINFTEDCPKSLLIPYLDNLVKHLHSIMVLKLQELIQKGTKLVLEQVVTSIASVADTAEEKFVPYYDLFMPSLKHIVENAVQKELRLLRGKTIECISLIGLAVGKEKFMQDASDVMQLLLKTQTDFNDMEDDDPQISYMISAWARMCKILGKEFQQYLPVVMGPLMKTASIKPEVALLDTQDMENMSDDDGWEFVNLGDQQSFGIKTAGLEEKSTACQMLVCYAKELKEGFVEYTEQVVKLMVP-LLKFYFHDGVRVAAAESMPLLLECARVRG---PEYLTQMWHFMCDALIKAIGTEPDSDVLSEIMHSFAKCIEVMGDGCLNNEHFEELGGILKAKLEEHFKNQELRQVKRQDEDYDEQVEESLQDEDDNDVYILTKVSDILHSIFSSYKEKVLPWFEQLLPLIVNLICPHRPWPDRQWGLCIFDDIIEHCSPASFKYAEYFLRPMLQYVCDNSPEVRQAAAYGLGVMAQYGGDNYRPFCTEALPLLVRVIQSADSKTKENVNATENCISAVGKIMKFKPDCVN-VEEVLPHWLSWLPLHEDKEEAVQTFSYLCDLIESNHPIVLGPN--NTNLPKIFSIIAEGEMHEAIKHEDPCAKRLANVVRQVQTSGGLWTECIAQLSPEQQAAIQ----ELLNSA--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O00410-1", "uniprot_id": "IPO5_HUMAN", "id": "O00410-1", "name": "Importin-5", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------MAAAAAEQQQFYLLLGNLLSPDNVVRKQAEETYENIPGQSK----ITFLLQAIRNTTAAEEARQMAAVLLRRLLSSAFDEVYPALPSDVQTAIKSELLMIIQMETQSSMRKKVCDIAAELARNLIDEDGNN---QWPEGLKFLFDSVSSQNVGLREAALHIFWNFPGIFGNQQQHYLDVIKRMLVQCMQDQEHPSIRTLSARATAAFILAN--EHNVALFKHFADLLPGFLQAVNDSCYQNDD-SVLKSLVEIADTVPKYLRPHLEATLQLSLKLCGDTSLNNMQRQLALEVIVTLSETAAAMLRKHTN----IVAQTIPQMLAMMVDLEEDEDWANADELEDDDFDSNAVAGESALDRMACGLGGKLVLPMIKEHIMQMLQNPDWKYRHAGLMALSAIGEGCHQQMEGILNEIVNFVLLFLQDPHPRVRYAACNAVGQMATDFAPGFQKKFHEKVIAALLQTMEDQGNQRVQAHAAAALINFTEDCPKSLLIPYLDNLVKHLHSIMVLKLQELIQKGTKLVLEQVVTSIASVADTAEEKFVPYYDLFMPSLKHIVENAVQKELRLLRGKTIECISLIGLAVGKEKFMQDASDVMQLLLKTQTDFNDMEDDDPQISYMISAWARMCKILGKEFQQYLPVVMGPLMKTASIKPEVALLDTQDMENMSDDDGWEFVNLGDQQSFGIKTAGLEEKSTACQMLVCYAKELKEGFVEYTEQVVKLMVP-LLKFYFHDGVRVAAAESMPLLLECARVRG---PEYLTQMWHFMCDALIKAIGTEPDSDVLSEIMHSFAKCIEVMGDGCLNNEHFEELGGILKAKLEEHFKNQELRQVKRQDEDYDEQVEESLQDEDDNDVYILTKVSDILHSIFSSYKEKVLPWFEQLLPLIVNLICPHRPWPDRQWGLCIFDDVIEHCSPASFKYAEYFLRPMLQYVCDNSPEVRQAAAYGLGVMAQYGGDNYRPFCTEALPLLVRVIQSADSKTKENVNATENCISAVGKIMKFKPDCVN-VEEVLPHWLSWLPLHEDKEEAVQTFNYLCDLIESNHPIVLGPN--NTNLPKIFSIIAEGEMHEAIKHEDPCAKRLANVVRQVQTSGGLWTECIAQLSPEQQAAIQ----ELLNSA--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BKC5-1", "uniprot_id": "IPO5_MOUSE", "id": "Q8BKC5-1", "name": "Importin-5", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------MAAAAAEQQQFYLLLGNLLSPDNVVRKQAEETYENIPGRSK----ITFLLQAIRNTTAAEEARQMAAVLLRRLLSSAFDEVYPALPSDVQTAIKSELLMIIQMETQSSMRKKICDIAAELARNLIDEDGNN---QWPEGLKFLFDSVSSQNMGLREAALHIFWNFPGIFGNQQQHYLDVIKRMLVQCMQDQEHPSIRTLSARATAAFILAN--EHNVALFKHFADLLPGFLQAVNDSCYQNDD-SVLKSLVEIADTVPKYLRPHLEATLQLSLKLCGDTNLNNMQRQLALEVIVTLSETAAAMLRKHTS----LIAQTIPQMLAMMVDLEEDEDWANADELEDDDFDSNAVAGESALDRMACGLGGKLVLPMIKEHIMQMLQNPDWKYRHAGLMALSAIGEGCHQQMEGILNEIVNFVLLFLQDPHPRVRYAACNAVGQMATDFAPGFQKKFHEKVIAALLQTMEDQGNQRVQAHAAAALINFTEDCPKSLLIPYLDNLVKHLHSIMVLKLQELIQKGTKLVLEQVVTSIASVADTAEEKFVPYYDLFMPSLKHIVENAVQKELRLLRGKTIECISLIGLAVGKEKFMQDASDVMQLLLKTQTDFNDMEDDDPQISYMISAWARMCKILGKEFQQYLPVVMGPLMKTASIKPEVALLDTQDMENMSDDDGWEFVNLGDQQSFGIKTAGLEEKSTACQMLVCYAKELKEGFVEYTEQVVKLMVP-LLKFYFHDGVRVAAAESMPLLLECARVRG---PEYLTQMWHFMCDALIKAIGTEPDSDVLSEIMHSFAKCIEVMGDGCLNNEHFEELGGILKAKLEEHFKNQELRQVKRQDEDYDEQVEESLQDEDDNDVYILTKVSDILHSIFSSYKEKVLPWFEQLLPLIVNLICPQRPWPDRQWGLCIFDDIVEHCSPASFKYAEYFISPMLQYVCDNSPEVRQAAAYGLGVMAQFGGDNYRPFCTDALPLLVRVIQAPEAKTKENVNATENCISAVGKIMKFKPDCVN-VEEVLPHWLSWLPLHEDKEEAVQTFSYLCDLIESNHPIVLGPN--NTNLPKIFSIIAEGEMHEAIKHEDPCAKRLANVVRQVQTSGGLWTECIAQLSPEQQAAIQ----ELLNSA--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VN44-1", "uniprot_id": "Q9VN44_DROME", "id": "Q9VN44-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------MAADQAHFQQLLASLLSTDNDVRQQAEEAYNNLSRELK----VTHLLGNIQNGQQSEEARQMAAVLLRRLFTTEFFDFYKGLPAESQNQLLQQILLAVQQEVTPQLRRKICEVVAEVARNLIDEDCNN---QWPDILQFLFQCANSPTPQLQESALRIFSSVPSIFGNQEAQYIDLIKQMLAKSMDAGSDPEVRVQAVRAVGAFILYHDKENETAIHKHFADMLPRMIHITGETIEAQDDQSLLKLLIEMTENCPKFLRPQLEFIFEVCMKVFSSQDFEDSWRHLVLEVMVSLAENAPSMIRKRADK---YIVALIPLILHMMTDLDDDENWSTADVVDDDDHSDNNVIAESSLDRLACGLGGKIVLPLVMNALPVMLGHADWKHRFAALMAISAIGEGCHKQMEAILDEVMSGVLNFLSDPHPRVRYAACNAIGQMSTDFAQTFEKKFHSQVIPGLLSLLDDVENPRVQAHAGAALVNFSEDCPKNILTRYLDGIMAKLETILNSKFKELVEKGNKLVLEQVVTTIASVADTCESEFVAYYDRLMPCLKFIIQNANSDDLRMLRGKTIECVSLIGLAVGREKFIGDAGEVMDMLLVNHTEGGELADDDPQTSYLITAWARMCKILGKQFEQYLPLVMGPVMRTATMKPEVAMLDNDEVEDIDGDVDWSFINLGEQQNFAIRTAGMDDKASACEMLVCYARELKEGFAEYAEDVVRQMLP-MLKFYFHDGVRTAAAESLPYLLDCAKIKG---PQYLEGMWMFICPELLKVIVTEPEPDVQSELLNSLAKCIETLGPNCLNEDAMKQVLEIINKYVLEHFERADKRLAARNEEDYDDGVEEELAEQDDTDVYILSKIVDITHALFQTNKAQFLPAFEQVAPHFVKLLEPSRPVADRQWGLCVFDDLIEFCGPACAPYQQIFTPALVQYVCDKAPEVRQAAAYGCGVLGQFAGEQFAHTCAQIIPLLVQVINDPKAREIENISPTENAISAFAKILKYNNSALSNVDELIGVWFSWLPVSEDSEEAAHIYGYLCDLIEGNHPVILGAN--NGNLPRIVSIIAESFCTKVVEAQSATGTRMLTIVKQVESNPEVMAACASTLSPEQQQALQDAYRELANVAPA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32337-1", "uniprot_id": "IMB3_YEAST", "id": "P32337-1", "name": "Importin subunit beta-3", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------MSALPEEVNRTLLQIVQAFASPDNQIRSVAEKALSEEWITENNIEYLLTFLAEQAAFSQDTTVAALSAVLFRKLALKAPPSSKLMIMSKNITHIRKEVLAQIRSSLLKGFLSERADSIRHKLSDAIAECVQDDLPAWPELLQALIESLKSGNPNFRESSFRILTTVPYLITAVD---INSILPIFQSGFTDASDN-VKIAAVTAFVGYFKQLPKSEWSKLGILLPSLLNSLPRFLDDGKDDALA-SVFESLIELVELAPKLFKDMFDQIIQFTDMVIKNKDLEPPARTTALELLTVFSENAPQMCKSNQNYGQTLVMVTLIMMTEVSIDDDDAAEWIESDDTDDEEE-VTYDHARQALDRVALKLGGEYLAAPLFQYLQQMITSTEWRERFAAMMALSSAAEGCADVLIGEIPKILDMVIPLINDPHPRVQYGCCNVLGQISTDFSPFIQRTAHDRILPALISKLTSECTSRVQTHAAAALVNFSEFASKDILEPYLDSLLTNLLVLLQS--------NKLYVQEQALTTIAFIAEAAKNKFIKYYDTLMPLLLNVLK-VNNKDNSVLKGKCMECATLIGFAVGKEKFHEHSQELISILVALQN--SDIDEDDALRSYLEQSWSRICRILGDDFVPLLPIVIPPLLITAKATQDVGLIEEEEAANFQQYPDWDVVQVQG-KHIAIHTSVLDDKVSAMELLQSYATLLRGQFAVYVKEVMEEIALPSLDFYLHDGVRAAGATLIPILLSCLLAATGTQNEELVLLWHKASSKLIGGLMSEPMPEITQVYHNSLVNGIKVMGDNCLSEDQLAAFTKGVSANLTDTYERMQDRHG--DGDEYNENIDE---EEDFTDEDLLDEINKSIAAVLKTTNGHYLKNLENIWPMINTFLLDNEPIL-VIFALVVIGDLIQYGGEQTASMKNAFIPKVTECLISPDARIRQAASYIIGVCAQYAPSTYADVCIPTLDTLVQIVDFPGSKLEENRSSTENASAAIAKILYAYNSNIPNVDTYTANWFKTLPTITDKEAASFNYQFLSQLIENNSPIVCAQSNISAVVDSVIQALNERSLTEREGQTVISSVKKLLGFLPSSDAMAIFNRYPADIMEKVHKWFA------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :: : *.** :*. **:: .: : : :* . ::***:*:* . . : :. . : .::* :: . : : .: . : * * :: **: *: *::. .* . ::*::::*: ..* :: : :: * :: . : .. :: :. * .:: .. : :..:* : : .: *::: *:*:.: ** :: :: ::. : . .:: * .**::. ::*.*. * :.. . : : : : * :: :* :* :*:: . ...:***:* ***: : . : : : *: .:*: *.*.:**:*: .*** . : . : :::. *: ::.******:*..**.:**::***: :::. *.:::..*:. : . . ***:**.***:**:* ..*.:* ***.:: :* :: .. * **.:*:** :*::.:.:*: *** :** * ::: . ..: :*:** :** :***:***:*** .: :::.:*: :. .:: :**. **: :*:*:*:***.:* **:*: *:: **. . :*.::: :: ::. .*..::: : :.*:*: :::* :* ::* .** *: *. *.::*:. : *.**:*****.*.* :* **.* : * :* . *: : :** .:: . :*:.: *:.:* .**.:: : . :. : : ::. : * : ::*:: ::* ::* .* :* :: . :::.: : : * :*:: * : .:: .* :.* ::.*:::. . : * : : : . ..:****:* ** .*:. . : * : **:::: . :: ** ..***. :*..**: . : *: *:. ** *.* * : :*.:***.* *:: . . . : :.. : * : . : . . : : : : : : ", "identical_positions": 221, "similar_positions": 427, "identity": "17.42%" }, { "cls_id": "homologset.agr.RGD:1308717", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "G3V918-1", "uniprot_id": "G3V918_RAT", "id": "G3V918-1", "name": "Trifunctional purine biosynthetic protein adenosine-3", "aln": "MAARVLVIGSGGREHTLAWKLAQSPHVKQVLVAPGNAGTASAGKISN----AAVSINDHTALARFCKDEKIELVVVGPEAPLAAGIVGDLTSAGVRCFGPTAQAALLESSKKFAKEFMDRHGVPTAQWRAFTSPEDACSFIMSADFPALVVKASGLAAGKGVIVAKSKAEACEAVQEIMQEKSFG-AAGETVVVEELLEGEEVSCLCFTDGKTVAPMPPAQDHKRLLDGDRGPNTGGMGAYCPAPQVPKDLLVKIKNTILQRTVDGMQQEGVPYTGILYAGIMLTKDG------PKVLEFNCRFGDPECQVILPLLK--SDLYEVIQSTFDGLLSESPPVWLENHSAVTVVMASGGYPGAYTKGVEITGFPEAQALGLQVFHAGTALKDAK--VVTSGGRVLTVTAVRENLMSALDEARKGLAALKFEG--AVYRKDIGFRAVAFLQRPR-GLTYKDSGVDIAAGNMLVKKIQPLAKATSRPGCSVDLGGFAGLFDLKAAGFK---DPLLASGTDGVGTKLKIAQLCNKHDSIGQDLVAMCVNDILAQGAEPLFFLDYFSCGKLDLSTTEAVVAGIAAACRQAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMER----------------------------------------------------------------------HQKLPQLER----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IAEGDAVIGVASSGLHSNGFSLVRKIVERSSLQYSSPAPGGCGDQTLGDLLLTPTRIYSHSLLPIIRSG--RVKAFAHITGGGLLENIPRVLPRKLGVDLDAYTWRVPKVFSWLQQEGQLSEEEMARTFNCGVGAALVVSKDQTEQILHDIRQHQEDAWVIGSVVECPE-DSPRVRVKNLIETMQTKGSVVTNGFLRSNFPSQQKKARVAVLISGTGSNLQALIDSTRDPKS--SSHIVLVISNKAAVAGLDRAERAGIPTRVINHKLYKSRVEFDNAVDHVLEEFSVDIVCLAGFMRILSGPFVRKWDGKMLNIHPSLLPSFKGSNAHEQVLEAGVTITGCTVHFVAEDVDAGQIILQEAVPVQRDDTVATLSERVKAAEHKIFPAALQLVASGAVQLGEDGKIHWAREQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q64737-1", "uniprot_id": "PUR2_MOUSE", "id": "Q64737-1", "name": "Trifunctional purine biosynthetic protein adenosine-3", "aln": "MAARVLVIGSGGREHTLAWKLAQSPQVKQVLVAPGNAGTACAGKISN----AAVSVNDHSALAQFCKDEKIELVVVGPEAPLAAGIVGDLTSAGVRCFGPTAQAAQLESSKKFAKEFMDRHEIPTAQWRAFTNPEDACSFITSANFPALVVKASGLAAGKGVIVAKSQAEACRAVQEIMQEKSFG-AAGETVVVEEFLEGEEVSCLCFTDGKTVAEMPPAQDHKRLLDGDEGPNTGGMGAYCPAPQVSKDLLVKIKNTILQRAVDGMQQEGAPYTGILYAGIMLTKDG------PKVLEFNCRFGDPECQVILPLLK--SDLYEVMQSTLDGLLSASLPVWLENHSAVTVVMASKGYPGAYTKGVEITGFPEAQALGLQVFHAGTALKDGK--VVTSGGRVLTVTAVQENLMSALAEARKGLAALKFEG--AIYRKDIGFRAVAFLQRPR-GLTYKDSGVDIAAGNMLVKKIQPLAKATSRPGCSVDLGGFAGLFDLKAAGFK---DPLLASGTDGVGTKLKIAQLCNKHDSIGQDLVAMCVNDILAQGAEPLFFLDYFSCGKLDLSTTEAVIAGIAAACQQAGCALLGGETAEMPNMYPPGEYDLAGFAVGAMER----------------------------------------------------------------------HQKLPQLER----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ITEGDAVIGVASSGLHSNGFSLVRKIVERSSLQYSSPAPGGCGDQTLGDLLLTPTRIYSHSLLPIIRSG--RVKAFAHITGGGLLENIPRVLPQKFGVDLDASTWRVPKVFSWLQQEGELSEEEMARTFNCGIGAALVVSKDQAEQVLHDVRRRQEEAWVIGSVVACPE-DSPRVRVKNLIETIQTNGSLVANGFLKSNFPVQQKKARVAVLISGTGSNLQALIDSTRDPKS--SSHIVLVISNKAAVAGLDRAERAGIPTRVINHKLYKNRVEFDNAVDHVLEEFSVDIVCLAGFMRILSGPFVRKWDGKMLNIHPSLLPSFKGSNAHEQVLEAGVTITGCTVHFVAEDVDAGQIILQEAVPVRRGDTVATLSERVKVAEHKIFPAALQLVASGAVQLREDGKIHWAKEQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P22102-1", "uniprot_id": "PUR2_HUMAN", "id": "P22102-1", "name": "Trifunctional purine biosynthetic protein adenosine-3", "aln": "MAARVLIIGSGGREHTLAWKLAQSHHVKQVLVAPGNAGTACSEKISN----TAISISDHTALAQFCKEKKIEFVVVGPEAPLAAGIVGNLRSAGVQCFGPTAEAAQLESSKRFAKEFMDRHGIPTAQWKAFTKPEEACSFILSADFPALVVKASGLAAGKGVIVAKSKEEACKAVQEIMQEKAFG-AAGETIVIEELLDGEEVSCLCFTDGKTVAPMPPAQDHKRLLEGDGGPNTGGMGAYCPAPQVSNDLLLKIKDTVLQRTVDGMQQEGTPYTGILYAGIMLTKNG------PKVLEFNCRFGDPECQVILPLLK--SDLYEVIQSTLDGLLCTSLPVWLENHTALTVVMASKGYPGDYTKGVEITGFPEAQALGLEVFHAGTALKNGK--VVTHGGRVLAVTAIRENLISALEEAKKGLAAIKFEG--AIYRKDVGFRAIAFLQQPR-SLTYKESGVDIAAGNMLVKKIQPLAKATSRSGCKVDLGGFAGLFDLKAAGFK---DPLLASGTDGVGTKLKIAQLCNKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSCGKLDLSVTEAVVAGIAKACGKAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMER----------------------------------------------------------------------DQKLPHLER----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ITEGDVVVGIASSGLHSNGFSLVRKIVAKSSLQYSSPAPDGCGDQTLGDLLLTPTRIYSHSLLPVLRSG--HVKAFAHITGGGLLENIPRVLPEKLGVDLDAQTWRIPRVFSWLQQEGHLSEEEMARTFNCGVGAVLVVSKEQTEQILRDIQQHKEEAWVIGSVVARAE-GSPRVKVKNLIESMQINGSVLKNGSLTNHFSFEKKKARVAVLISGTGSNLQALIDSTREPNS--SAQIDIVISNKAAVAGLDKAERAGIPTRVINHKLYKNRVEFDSAIDLVLEEFSIDIVCLAGFMRILSGPFVQKWNGKMLNIHPSLLPSFKGSNAHEQALETGVTVTGCTVHFVAEDVDAGQIILQEAVPVKRGDTVATLSERVKLAEHKIFPAALQLVASGTVQLGENGKICWVKEE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P00967-1", "uniprot_id": "PUR2_DROME", "id": "P00967-1", "name": "Trifunctional purine biosynthetic protein adenosine-3", "aln": "MSHRVLVIGSGGREHAICWKLSQSPKVAQIYALPGSHGIQLVEKCRNL-DAKTLDPKDFEAIAKWSKENQIALVVVGPEDPLALGLGDVLQSAGIPCFGPGKQGAQIEADKKWAKDFMLRHGIPTARYESFTDTEKAKAFIRSAPYPALVVKAAGLAAGKGVVVAANAKEACQAVDEILGDLKYG-QAGATLVVEELLEGEEVSVLAFTDGKSVRAMLPAQDHKRLGNGDTGPNTGGMGAYCPCPLISQPALELVQKAVLERAVQGLIKERINYQGVLYAGLMLTRDG------PRVLEFNCRFGDPETQVILPLLE--SDLFDVMEACCSGKLDKIPLQWRNGVSAVGVILASAGYPETSTKGCIISGLPAANTPTQLVFHSGLAVNAQKE-ALTNGGRVLIAIALDGSLKEAAAKATKLAGSISFSGSGAQYRTDIAQKAFKIASASTPGLSYKDSGVDIDAGDALVQRIKPLSRGTQRPGVIGGLGGFGGLFRLKELTYK---EPVIAEATQGVGAKIHLALTHELYENVGYDLFALAANDVLEVGAEPVAFLDYIACGKLQVPLAAQLVKGMADGCRDARCALVGGETAEMPSLYAPGQHDMAGYCVGIVEQSRILPRFDLYQPGDLLIGLPSSGLHCAGFNEILTQLAASKVNLRERSPVDGGDDGLTLAHVLATPTQLYVQQLLPHLQKGDEIKSVAHVTHGLLNDILRLLPDGFETTLDFGAVPVPKIFGWLAGKLKLSAQTILERHNCGIGMVLILPQSSQLWRTSLPGAKVLGVLQRRSKVSGSPVQVRNFVEQLEKVASPFGGLGDRELPEELKKLPSNSDLSAPREECFENAAGRRLTRIPTHYKDPILILGTDGVGTKLKIAQQTNRNTSVGIDLVAMCVNDILCNGAEPISFSSYYACGHWQEQLAKEVHSGVQEGARQANSSFIDSHSAALPLLYEPQVYDLAGFALGIAEHTGILPLLDEIQPGDVLIGLPSSGVHSNGFSLVHAVLKRVGLGLHDKAP--FSDKTLGEELLVPTKIYVKALSTLLSRGKHGIKALAHITGGGLSENIPRVLRKDLAVRLDANKFQLPPVFAWLAAAGNISSTELQRTYNCGLGMVLVVAPTEVEDVLKELR-YPQRAAVVGEVVARKDPKKSQVVVQNFEASLARTQKMLS-----------QRRKRVAVLISGTGSNLQALIDATRDSAQGIHADVVLVISNKTGVLGLQRATQAGIPSLVISHKDFASREVYDAELTRNLKAARVDLICLAGFMRVLSAPFVREWRGRLVNIHPSLLPKYPGLHVQKQALEAGEKESGCTVHFVDEGVDTGAIIVQAAVPILPDDDEDSLTQRIHKAEHWAFPRALAMLVNGTALISPEVSSQ-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P07244-1", "uniprot_id": "PUR2_YEAST", "id": "P07244-1", "name": "Bifunctional purine biosynthetic protein ADE5,7", "aln": "-MLNILVLGNGAREHVLVTKLAQSPTVGKIYVAPGNGGTATMDPSRVINWDITPDVANFARLQSMAVEHKINLVVPGPELPLVNGITSVFHSVGIPVFGPSVKAAQLEASKAFSKRFMSKHNIPTASYDVFTNPEEAISFLQAHTDKAFVIKADGIAAGKGVIIPSSIDESVQAIKDIMVTKQFGEEAGKQVVIEQFLEGDEISLLTIVDGYSHFNLPVAQDHKRIFDGDKGLNTGGMGAYAPAPVATPSLLKTIDSQIVKPTIDGMRRDGMPFVGVLFTGMILVKDSKTNQLVPEVLEYNVRFGDPETQAVLSLLDDQTDLAQVFLAAAEHRLDSVNIGIDDTRSAVTVVVAAGGYPESYAKGDKITLDTDKLPPHTQIFQAGTKYDSATDSLLTNGGRVLSVTSTAQDLRTAVDTVYEAVKCVHFQN--SYYRKDIAYRAFQNSESSKVAITYADSGVSVDNGNNLVQTIKEMVRSTRRPGADSDIGGFGGLFDLAQAGFRQNEDTLLVGATDGVGTKLIIAQETGIHNTVGIDLVAMNVNDLVVQGAEPLFFLDYFATGALDIQVASDFVSGVANGCIQSGCALVGGETSEMPGMYPPGHYDTNGTAVGAVLR----------------------------------------------------------------------QDILPKINE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAGDVLLGLASSGVHSNGFSLVRKIIQHVALPWDAPCP-WDESKTLGEGILEPTKIYVKQLLPSIRQR--LLLGLAHITGGGLVENIPRAIPDHLQARVDMSTWEVPRVFKWFGQAGNVPHDDILRTFNMGVGMVLIVKRENVKAVCDSLTEEGEIIWELGSLQERPK-DAPGCVIEN-------------------------------------GTKLY----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:*::*.*.***.: **:** * :: . **. * : . :. : . :.:* :** *** **. *: . : *.*: *** :.* :*:.* ::* ** :* :*** : **..*.* :*: : *:*:** *:******::. . *: .*:.:*: :* ** :*:*::*:*:*:* * :.** : : ******: :** * ********.*.* . * :.. ::: :::*: :: : *:*::*::*.::. *.***:* ****** *.:*.**. :** :*: : . * : :*: *::*: *** :** *: . . :*::* . . :* ***** . : .* * . : .: *.. : **.*:. :*. . . .::* :***.: *: **: *: : :.* *.* .:***.*** * :: :.::. .*:***:*: :* ::.:* **.*: .**:: ****: ****:: * *:: : .: *:* .* .: ***:****:***.:*.**.:* * .** : : .: **:::. : **.::*:.***:********: :: : .* .* .:***: :* **:** : * . : : .:******** *****.: .: . :* .:.:* ** *: *.:. :: **:* *:* .*:* :.: : .: : :*.: . . ::* *::* ", "identical_positions": 254, "similar_positions": 266, "identity": "18.33%" }, { "cls_id": "homologset.agr.RGD:1308718", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q568Z7-1", "uniprot_id": "CIB2_RAT", "id": "Q568Z7-1", "name": "Calcium and integrin-binding family member 2", "aln": "MGNKQTIFTEEQLDNYQDCTFFNKKDILKLHARFYELAPNLVP--MDYRKSPIVHVPMSLIIQMPELRENPFKERIVEAFSEDGEGNLTFNDFVDMFSVLCESAPRELKANYAFKIYDFNTDNFICKEDLELTLARLTKSELDEDEVVLVCDKVIEEADLDGDGKLGFADFEDMIAKAPDFLSTFHIRI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z309-1", "uniprot_id": "CIB2_MOUSE", "id": "Q9Z309-1", "name": "Calcium and integrin-binding family member 2", "aln": "MGNKQTIFTEEQLDNYQDCTFFNKKDILKLHARFYELAPNLVP--MDYRKSPIVHVPMSLIIQMPELRENPFKERIVEAFSEDGEGNLTFNDFVDMFSVLCESAPRELKANYAFKIYDFNTDNFICKEDLEMTLARLTKSELEEDEVVLVCDKVIEEADLDGDGKLGFADFEDMIAKAPDFLSTFHIRI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75838-1", "uniprot_id": "CIB2_HUMAN", "id": "O75838-1", "name": "Calcium and integrin-binding family member 2", "aln": "MGNKQTIFTEEQLDNYQDCTFFNKKDILKLHSRFYELAPNLVP--MDYRKSPIVHVPMSLIIQMPELRENPFKERIVAAFSEDGEGNLTFNDFVDMFSVLCESAPRELKANYAFKIYDFNTDNFICKEDLELTLARLTKSELDEEEVVLVCDKVIEEADLDGDGKLGFADFEDMIAKAPDFLSTFHIRI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PC72-1", "uniprot_id": "CIB2_DANRE", "id": "Q6PC72-1", "name": "Calcium and integrin-binding family member 2", "aln": "MGNKQTIFTDEQLDAYQDCTFFTRKEILRLHGRYHELAPHLVP--MDYTNDPDVKVPLALIVNMPELKENPFRNRIVESFSEDGQGNLSFNDFVDMFSVLSEMAPRELKAIYAFKIYDFNVDNYICKEDLEKTLNKLTKEELTPEEVNLVCEKAIEEADLDGDNKLSFADFENMISRAPDFLSTFHIRI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W2Q5-1", "uniprot_id": "CIB2_DROME", "id": "Q9W2Q5-1", "name": "Calcium and integrin-binding family member 2", "aln": "MGNKVVTFTEQELDDYQDCTFFTRKEILRVHKRFRELRPDLVPRQMTEGQASSVKVPCECIEKMPELRENPFRRRICEAFSRDGQGNLSFEDFLDALSVFSEQAPRDIKVFYAFKIYDFDQDGFIGHADLMSCLTTMTKNELSPEEHQQIADKVIEEADVDGDGKLSILEFEHVILRAPDFLSTFHIRI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**** . **:::** *******.:*:**::* *: ** *.*** * : . *:** * :****:****:.** :**.**:***:*:**:* :**:.* ***::*. ********: *.:* : ** * :**.** :* :.:*.*****:***.**.: :**.:* :************", "identical_positions": 103, "similar_positions": 49, "identity": "54.5%" }, { "cls_id": "homologset.agr.RGD:1308719", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A4W2-1", "uniprot_id": "A0A8I6A4W2_RAT", "id": "A0A8I6A4W2-1", "name": "", "aln": "MELHESTYFVVLIPSVVITVIFLFFWLFMKETLYDDVLAKQKREQKLISTKADKKKAEKKKNKKKEIQNGTLHESDSEHVPQDFKLSDASPVEDEQFVPAPLSVAETSSSVRERKKKEKKQKPSLEEHIIKESDASKIPGKKVEPVLVTEQPAPPP--EAAALKKKAGQKKSKNGSDELDKKVEMVMAPSQKQDGSLFHQETKQEGGPGKKKGLSKKQKTENVAVLVDEPLTHATASVPSVDNADSSLMTDKRGVTDMIKPDQVEGIQKSGTKKLKIDTDKENAEVKFKNFLLSLKTMMFSEDEALCVVDLLKEKSGVIKEALKKSNKGELSGLLHQLQEKERLLTATKEDAAATKERCKQLTQEMMTEKERSSVVMARMKERIGTLEKEHNIFQNKMHVSYQETQQMQMKFEQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQDCGRLVSELNEKTGKLQQEGVQKKNAEQAAAQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRASQEESMQIQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQLKQTEDSLASEQDHLASKEQELKDVQNVNFLLKAEVQKLQALAKEQAAAAHEVEKMQKSVHVKDDKIRLLEEQLQREVASRVEELKILNDQNKALQLEVQKLQAVVSEQPNKDVVEQMKKCIQEKDEKLRTVEELLETGLIQVATREEELNAIRTENSSLTKEVQELKAKQMDQVPFVSLIEDLKKVIHEKDGQIKSVEELLEVELLKVANKEKTVQALKQEIEILKEEIGNAQLEKAHQLSVTSQVQELQNLLRGKEEQVDSMKAALED----LTGREKCTQ-----------------------VCSTPRFEELENVLKEKDNEIKRIEAILKDTKSDLSKKAELLKEVQDENKLFKSQVEQLNHQNHQQAS-FPSQEELQTVISEKEKEITDLCNELESLKNAVEHQRKKNNDLREKNWEAMEALASTEKILQDRVNKTSKERQQQVEAVELESKDLLKRLFPAVSVPSHSNYSEWLRSFEKKAKACMAGPSDTEAVKVLEHRLKEANEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEESKWKVKAEESRRTIQQMQSSFTASEQELERLRHENKAMENLRREREHLEIELEKAEVERSTYVMEVRELKDLLTELQKKLDDSYSEAVRQNEELNLLKTQLNETHSKLQNEQTERKKVADDLHKAQQSLNFIHSKISLKAAGDTVVIENNDISPEMGSPEKETMSVSLTQTVAHLQQLLQEVNQQLTKEK-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61595-1", "uniprot_id": "KTN1_MOUSE", "id": "Q61595-1", "name": "Kinectin", "aln": "MELYESTYFIVLIPSVVITVIFLFFWLFMKETLYDEVLAKQKREQKLISTKTDKKKAEKKKNKKKEIQNGTLRESDSEHVPRDFKLSDASPAEDEQFVPAPLNVAETSSSVRERQKKEKKQKPSLEEQVIKESDASKIPGKKVEPVLVTKQPAPPPPLEAAALKKKAGQKKSKNGSEEQDKKVEMLMAPSKEQDVLLSHQDTKQEGGLGKKKGLSKKQKSENVAVLVDEPLIHATTYMP-LDNANSNLMMDKREIIDMIKPDHVEGIQKSGTKKLKIETDKENAEVKFKDFLLSLKTMMFSEDEALCVVDLLKEKSGVIKEALKKSNKGELSGLLHQLQEKERLLSAMKEDAAASKERCKRLTQEMMTEKERSSVVIARMKDRIGTLEKEHNIFQNKMHASYQETQQMQMKFQQVQEQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQDCGRLVSELNEKTGKLQQEGVQKKNAEQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRASKEESLQIQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQLKQTEDSLANEQDHLASKEEELKDVQNMNFLLKAEVQKWQALANEQAATAHEVEKMQKSIHVKEDEIRLLEEQLQHEVASKMEELKILSEQNKALQSEVRKLQTAVSQQPNKDVVEQMEKCIQEKDEKLRTVEELLETGLIQVATREEELSAIRTENSTLTREVQELKAKQSDQVSFVSLIEDLKRVIHEKDGQIKSVEELLEVELLKVANKEKTVQALKQEIEVLKEEIGNAQLEKAHQLSVTSQVQELQNLLRGKEEQVNSMKAALEDRDRGLTGRGTCAQ-----------------------VCSTPQFEELESVLKEKDNEIKRIEVKLKDTESDVSKMSELLKEVQEENKFLK---CQLSHQKHQQAS-FPSQEELQTVISEKEKEITDLCNELESLKNAVEHQRKKNNDLREKNWEAMEALASTEKMLQDRVNKTSKERRQHVEAIELESKDLLKRLFPTVSVPSNLNYSEWLRGFEKKAKACVAGTSDAEAVKVLEHRLKEASEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEESKWKIKADESQRMIKQMQSSFTASERELERLRQENKDMENLRREREHLEMELEKAEMERSTYVMEVRELKDLLTELQKKLDDSYSEAVRQNEELNLLKTQLNETHSKLQNEQTERKKVADDLHKAQQSLNSIHSKISLKAAGDTVVIENSDISPEMESPEKETMSVSLNQTVTQLQQLLQEVNQQLTKET-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86UP2-1", "uniprot_id": "KTN1_HUMAN", "id": "Q86UP2-1", "name": "Kinectin", "aln": "MEFYESAYFIVLIPSIVITVIFLFFWLFMKETLYDEVLAKQKREQKLIPTKTDKKKAEKKKNKKKEIQNGNLHESDSESVPRDFKLSDALAVEDDQVAPVPLNVVETSSSVRERKKKEKKQKPVLEEQVIKESDASKIPGKKVEPVPVTKQPTPPS--EAAASKKKPGQKKSKNGSDDQDKKVETLMVPSKRQEALPLHQETKQESGSGKKKASSKKQKTEN--VFVDEPLIHATTYIPLMDNADSSPVVDKREVIDLLKPDQVEGIQKSGTKKLKTETDKENAEVKFKDFLLSLKTMMFSEDEALCVVDLLKEKSGVIQDALKKSSKGELTTLIHQLQEKDKLLAAVKEDAAATKDRCKQLTQEMMTEKERSNVVITRMKDRIGTLEKEHNVFQNKIHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELLKVISEREKEISGLWNELDSLKDAVEHQRKKNNDLREKNWEAMEALASTEKMLQDKVNKTSKERQQQVEAVELEAKEVLKKLFPKVSVPSNLSYGEWLHGFEKKAKECMAGTSGSEEVKVLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRSENKDIENLRREREHLEMELEKAEMERSTYVTEVRELKDLLTELQKKLDDSYSEAVRQNEELNLLKAQLNETLTKLRTEQNERQKVAGDLHKAQQSLELIQSKI-VKAAGDTTVIENSDVSPETESSEKETMSVSLNQTVTQLQQLLQAVNQQLTKEKEHYQVLE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**::**:**:*****:*******************:************.**:******************.*:***** **:******* ..**:*..*.**.*.*********:******** ***::***************** **:**:**. **** ***.*********:: ***** :*.**:.*: **:****.* ****. *****:** *:***** ***: :* :***:*. : *** : *::***:************* :***********:*****************************::*****.****: *:******::**:* ******:*:***:************.**::***:**********:****:*.************:**:****************************************** .***.**.********* **********:****************************************************************************..:***:*:**********************************************:********.*:*:*:***:****:**:********** ****:****:***:****:*::**:*:*********:*::.::**:***.:*****: **:***: **:**********:**********:***************:****.*******:**:***:***** ***.*.**:*:**:*******:*********.************* *****: *******.*****:***:**:********:*****:::***.**: *:. . * ..*:.:***** *****:**:**:*. **: :**:*. ::**::**:***::* **.:*::**** **.:*** .****:****:.* ***:***:****************************:***:********:*:***:***:*::**:*** *****: .*.***:.****** *:**.*.:* ******:****.***********************************.***:*.:**:: *:*******:**:****** *** :***********:******:****** **********************************:***** :**:.**.**:***.*********: *:*** :******.****.*:*** *.*********.***::****** ********. ", "identical_positions": 1046, "similar_positions": 218, "identity": "76.8%" }, { "cls_id": "homologset.agr.RGD:1308720", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "F7ENR3-1", "uniprot_id": "F7ENR3_RAT", "id": "F7ENR3-1", "name": "", "aln": "---------------------------------------------------------------MAPGPP---ALLLLLLG----------------------------LLLLPLLPGLPPRATGCPAACRCYS----ATVECGALRLRVVPPGIPPGTQTLFLQDNSIAHLEQG--ALAPLAALRHLYLHNNTLRALESGAFRAQPRLLELALTGNRLRGLRGGAFVGLVQLRVLYLAGNQLAKLLDFTFLHLPRLQELHLQENSIELLEDQALAGLSS-LALLDLSRNQLGTISKEALQPLSSLQVLRLTENPWRCDCALHWLGSWIKEGGRRLLSSRDKKITCAE-PPRLALQSLLEVSGGSLICIPPSVNAEPPELTANLGEDLQVACQASGYPQPLVVWRKMLQ------PR--------DGK----------------------------------------------------------YECEATNAGGKARVLFHLLVN----------------------------------------------------------------------------------------------------------ASRQQSQQLPAP-----------------------------QAPATRPVGQEPQH---------------------------------------EGGSMAFRALGLATQTAITAAIALLALTALLLAAMICRRRRRRKKMP----VPSGE----------GTLFVNDYSDG-------PCTFAQLEELRDDHGHEMFVIDRSKPLFTEIPPEEP-------------------------PEHNPPEG-----------------------------------LRSGTRLPTRVAYEIHC--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BHA1-1", "uniprot_id": "LRC24_MOUSE", "id": "Q8BHA1-1", "name": "Leucine-rich repeat-containing protein 24", "aln": "---------------------------------------------------------------MALRAP---TLLLLLLG----------------------------LLLLPLLPGLPPRATGCPAACRCYS----ATVECGALRLRVVPPGIPPGTQTLFLQDNSIAHLEQG--SLAPLAALRHLYLHNNTLRALESGAFRAQPRLLELALTGNRLRGLRGGAFVGLVQLRVLYLAGNQLAKLLDFTFLHLPRLQELHLQENSIELLEDQALAGLSS-LALLDLSRNQLGTISKEALQPLSSLQVLRLTENPWRCDCALHWLGSWIKEGGRRLLSSRDKKITCAE-PPRLALQSLLEVSGGSLICIPPSVNVEPPEFTANLGEDLQVACQASGYPQPLVVWRKVPQ------PR--------DGKPQAQAQLEGGAPGLGGHGT-------------------RDTGSGMLFLTNITLAHAGKYECEAANAGGKARVPFHLLVN----------------------------------------------------------------------------------------------------------ASRQQSQQLPDP-----------------------------QAPATRPVGHEPQH---------------------------------------EAGSMAFRALGLATQTAITAAIALLALTALLLAAMICRRRRRRKKVP----APSGE----------GTLFVNDYSDG-------PCTFAQLEELRDDHGHEMFVIDRSKPLFPEVLPEEA-------------------------PEHNPPDG-----------------------------------LKSGLRLPTRVAYEIHC--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q50LG9-1", "uniprot_id": "LRC24_HUMAN", "id": "Q50LG9-1", "name": "Leucine-rich repeat-containing protein 24", "aln": "---------------------------------------------------------------MALRAP---ALLPLLL------------------------------LLLPLR------AAGCPAACRCYS----ATVECGALRLRVVPLGIPPGTQTLFLQDNNIARLEPG--ALAPLAALRRLYLHNNSLRALEAGAFRAQPRLLELALTSNRLRGLRSGAFVGLAQLRVLYLAGNQLARLLDFTFLHLPRLQELHLQENSIELLEDQALAGLSS-LALLDLSRNQLGTISREALQPLASLQVLRLTENPWRCDCALHWLGAWIKEGGQRLLTSRDRKIMCAE-PPRLALQSLLDVSHSSLICIPPSVHVQPLELTANLGEDLRVACQASGYPQPLVTWRKVPQ------PR--------EGRPRAQAQLEGGLLGLGGHSA-------------------SDTGSGMLFLSNITLAHAGKYECEASNAGGAARVPFRLLVN----------------------------------------------------------------------------------------------------------ASRQQPQQPAQP-----------------------------PPPAARPAGSEPRP---------------------------------------EAGSMAFRALGVATQTAIAAAIALLALTALLLVAMICRRRRRRKKAR----GPPGE----------GALFVNDYLDG-------PCTFAQLEELRDERGHEMFVINRSKPLFAEGPAEAP-------------------------ADCGPEQG-----------------------------------AGPGLRVPPPVAYEIHC--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B0J4-1", "uniprot_id": "A0A8M3B0J4_DANRE", "id": "A0A8M3B0J4-1", "name": "", "aln": "MLTLHLLPFLHRRIQFSDPLKRDSHALRIRLAHTCMRSLTTSPVLFFSLFFPSFGRLFRWLTAIHLCLS---SFLFPLFCPSSESLFYHSFFPVFCSVFSEMNPGQMSAVLVLMLAQLSSTSLACPSGCRCYS----LTVECGSIGIKEIPQGITQGTQTIFLQDNAIGQIRQR--DLSDLGQLHYLYLQNNSISTLEPGAFRSLGLLLELALNGNRIHLITADVFRGLDHLRILYLAGNQINRLEDYTFRGLQRLQELHLQENVLEVLGDQALVGLSS-LALLDLSRNNLRTLSPASLKPLVSLQVLRVTDNPWRCDCALHWLRGWINEEGQRLLSSAERRMLCAE-PPRLSHLSLVEVPPNSLVCIPPVVQLEPSHLTVRLGESLRVSCQASGYPQPQVTWRKASHGKAQLSPRGLVQEVGMDGDTRNGGRLVTARPGGKGGPSSHGPIRGGADDGADRENFDPDTGSGMLFLSNVTVAHAGRYECEAWNPGGVARVTFHLSVN----------------------------------------------------------------------------------------------------------MSSSSSRSEIWPRL----------------------HSSSYYHPSSVDVSQEPLY---------------------------------------ELESMDFNALGTATQTAIAVGISLLALTALLLLCMIYSRHRQRQKEEGGYGASKEE----------SILYVNDYSDG-------PTTFAQLEEYRDERGHEMYVLNRAKPVLAPQPMCIQQGSAT-LKASECQGVLTPGRAGGIGPRRAPAEGGEAPPLDPE-----------------------GLFMNQSLLFDTQIAYEIHC--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V430-1", "uniprot_id": "Q9V430_DROME", "id": "Q9V430-1", "name": "", "aln": "MAAGRAAATLEAPGPPSGQDIASDNSAQRRTLATKVRRKGPRPQR-------------RLHPPLRPRLP---LHLHLLLW------------------------------LLCCCSQLGQLRAECPAVCECKWKSGKESVLCLNANLTHIPQPLDAGTQLLDLSGNEIQLIPDDSFATAQLLNLQKVYLARCHLRLIERHAFRKLINLVELDLSQNLLSAIPSLALYHVSELRELRLSGNPILRVPDDAFGHVPQLVKLELSDCRLSHIAVRAFAGLESSLEWLKLDGNRLSEVRSGTITSLASLHGLELARNTWNCSCSLRPLRAWMLQQN----IPSGIPPTCES-PPRLSGRAWDKLDVDDFACVPQIVATDTTAHGVE-GRNITMSCYVEGVPQPAVKWLLKNRLIANLSAGG-------DGDSDSEPRTAAATQGRKTYVVN------------------MLRNASNLTILTADMQDAGIYTCAAENKAGKVEASVTLAVSRRPPEAPWGVRIILLGAVAALLLVGGSSFAAICLCSLQRRRKLRLWNSVPPVRRSESYEKIEMTARTRPDLGGGASCGGGSATGAGLFHDAEEQGYLRAAHTPLNDNDAGQAAAIVNPSAGSAQRRNGDYLHVSTHCDDEEEDQQLHHHPQQQPASQHHPHPNQQQHQQRKGSQGHVVSASGANNSAPLEETDLHIPRLIDIGGTDSASSSISSQVDAAARLAGYAGHTWKTTPIATTKINSPHSKPVTSAAPSSLNTQ-------ATPYAHYGNHP-------ADEMATSVFCSEGQESDLFDSNYPDLLDIAKYAVAQAQQEG-RGQGYAQATTTPNGGLCTLPRKLKTSGKYFRNSSDSQSPLLADNSSKYGSSTLGDGSFLNEAMGLGRRYSAESSYANYSSTATYTGGGQRANSFLNLVQSGAHQGKLLPSHLGQKPSLPSSPVQHQRSLSSAATPLLDFSALASRAAGAANTSVAAYDYHAAQLERFLEEYRNLQDQLCKMKETCDTIRKKETPLR-VAIGQSAAQLADPVMYSAASHSPKPPATSNLKTKTLLPGQPPDPPPYWLHRNAMLKRLNGDGSAGTNGSGGSPASPQPRQDIFKS---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VK54-1", "uniprot_id": "Q9VK54_DROME", "id": "Q9VK54-1", "name": "", "aln": "--MHIREAVFLVLTLLPGMILGTRYNQLHLYANGGASSSGPGGYRPAPSSQNEVYSIADSQPMTEDGYMPPSQHFPP---------------------------------THSDLDPPAQQQSTCQTVCACKWKGGKQTVECIDRHLIQIPEHIDPNTQVLDMSGNKLQTLSNEQFIRANLLNLQKLYLRNCKIGEIERETFKGLTNLVELDLSHNLLVTVPSLALGHIPSLRELTLASNHIHKIESQAFGNTPSLHKLDLSHCDIQTISAQAFGGLQG-LTLLRLNGNKLSELLPKTIETLSRLHGIELHDNPWLCDCRLRDTKLWLMKRN----IPYPVAPVCSGGPERIIDRSFADLHVDEFACRPEMLPIS-HYVEAAMGENASITCRARAVPAANINWYWNGRLLAN------------NSAFTAYQRIHMLEQVEGGFEKR-----------------------SKLVLTNAQETDSSEFYCVAENRAGMAEANFTLHVSMRAAG----------------------------------------------------------------------------------------------------MASLGSGQIVGLSAALVALIVFALGVIMCLLLRVKRQPYVDSKTPNHMEVITSVNHQN----------------------------------SITNKTQPATGNGSIGGVVIANGAVANIIDGGVVQGGTLERKSSGRGGVPHGVHDQRSANPVQKPPRLTDLPYSTQGYDNNGSVLSTASCFISPSGSTGNGGNNPDLINDTKRFGSDEFADLKIPPISGVGVGGSGEYSRANGCDSLYPSGLWEHGAPVGTTSADDLFMKR-------------------YTDKTPIIDSTQLYDLHER--------TAATDYFSKTFPRSHLQQGMMTGGGGGTSTASTVTTNLSGGSSSGYPNDYGLPLVPGAEHQHNHQLQMHPLQQLQQQLTSTLNHQKQEGSSTGSSPHFSSRTLPRLHEGSGGGGSSRSSPTPAVSGGHANQAANPSTSSSSCSILPNGQPINAKTIRVWQKGGVPVLPPVTALKRALISSSRNSPDEGYQEGCGTDV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VK22-1", "uniprot_id": "Q9VK22_DROME", "id": "Q9VK22-1", "name": "", "aln": "------------------------------------------------------MAIKLSFDPCSISLKHLSLFLFKIYC------------------------------LALIFRSASADWLLDCGNCHCKWNSGKKTADCRNLSLSGVPEYLSPEVQVLDLSHNHIFYLEENAFLTTHLQNLQKLLIRNGTLKYLNQRSFTQLQILIELDLSNNLLVDLLPNVFDCLSKVRAIFLNGNLLQALRHGVFRNLKYLHKIELKRNRLVSIDAKAFVGVPL-LSQIYLDNNELTKLRVESFQDLTKLTALSLVENPWNCTCDLQMFRDFVIGMN------LYTPPTSCHYPLQLRGRLWIEDQPEAFACKPKIVYPTLSTSINTSKENVTLICRVHGSPNTVIAWDYTNQVYESRSKP-------VKSLQKQRIYIELLREDESKIRKFG-----------------HDVFVSRLTIVNARKSDEGVYTCLAENPGGKDSVHISVVVQKDMER-----------------------------------------------------------------------------------------------------ISLIDSNFFAIVCLIAMG----------------FLSMSILFSLVTCLIFKRFKQFHPG------------------------------QHTYLQPTSLPVQSPGSEEATAISALSSGVIRESKIVLDPLSAINEPSNKNYTLFKTSNSN----------GSEYMHTRNYK-------DVRLNSNTYTENLDNQAESISSRNRELYSNIAGDRE-------------------------KEELKQKDE----------------------------------LDKDSRQSSLQSTGCSR--------------------------KKGQIDELQPDLLPSTQPTALKNINETFGPSAKKAEVNPRSKYNTNVQKYLKEKYGSVRIKNISTKEPITGVDISI--------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * * :. * : :* : .* : :. * : : : * *: : : . : :: :* *:** *. * : : .: : :* : * .* : : .* * ::.*. : : :*: *: * : *. *.* : :: * * : : *.* * * *: :: . . * :: . : * * : .. : * . . * . : * : .. : * * * .* . . : *. . . : . . : : : . . . . ", "identical_positions": 44, "similar_positions": 90, "identity": "3.94%" }, { "cls_id": "homologset.agr.RGD:1308721", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JHH2-1", "uniprot_id": "TSN32_MOUSE", "id": "Q9JHH2-1", "name": "Tetraspanin-32", "aln": "MGHWNRIKIAKCQILITNFLVLLLGLSMATMVVVIHFGDHFTVIGHASLERNPYETLRYWAFYVGISLAGLLSLGAALSTIATVREAHGLMAAGFLCFALSFCILVQVAFWRFYNPTQVEDAVLDTYDFVYDQAMKSPSSNWWQELAVIQDTFLCCGKKSPFGLLVSTGAIMCQGREAMREDCLQSIRNVLWTHYSIASILTCTSLALTVYAMMLCAFLWFAIHSYHGLDRKGRYSLTPPRSHGFQTQEPSLFRWT-----------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LD47-1", "uniprot_id": "A0ABK0LD47_RAT", "id": "A0ABK0LD47-1", "name": "Tetraspanin", "aln": "MGHWNRIKIAKCQILITNFFVLLLGLSLATMTVVTHFGDHFTVIGHASLQRNPYETLRYWAFYVGISLAGLLSLGAALSTIATVREAHGLMAAGFLCFALSFCILVQVAFWRFHNPTQVEDAVLDTYDLVYDQAMKSPSSSWWQELAVIQDTFLCCGKKSPFGLLASTGPIMCQGQKAMREDCLQSIRNFLWTHYRIASTLTCTSLALTVYAMMLCAFLWFAIHSYCGLDRRGRYSLTP-RSHGCQPQEPSLF--------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96QS1-1", "uniprot_id": "TSN32_HUMAN", "id": "Q96QS1-1", "name": "Tetraspanin-32", "aln": "MGPWSRVRVAKCQMLVTCFFILLLGLSVATMVTLTYFGAHFAVIRRASLEKNPYQAVHQWAFSAGLSLVGLLTLGAVLSAAATVREAQGLMAGGFLCFSLAFCAQVQVVFWRLHSPTQVEDAMLDTYDLVYEQAMKGTSHVRRQELAAIQDVFLCCGKKSPFSRLGSTEADLCQGEEAAREDCLQGIRSFLRTHQQVASSLTSIGLALTVSALLFSSFLWFAIRCGCSLDRKGKYTLTP-RACGRQPQEPSLLRCSQGGPTHCLHSEAVAIGPRGCSGSLRWLQESDAAPLPLSCHLAAHRALQGRSRGGLSGCPERGLSD", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** *.*:::****:*:* *::******:***..: :** **:** :***::***:::: *** .*:**.***:***.**: ******:****.*****:*:** ***.***::.*******:*****:**:****..* ****.***.**********. * ** . :***.:* ******.**..* ** :** **. .***** *:::.:******:. .***:*:*:*** *: * *.*****: ", "identical_positions": 156, "similar_positions": 67, "identity": "48.6%" }, { "cls_id": "homologset.agr.RGD:1308722", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CAV0-1", "uniprot_id": "YBEY_MOUSE", "id": "Q8CAV0-1", "name": "Endoribonuclease YbeY", "aln": "MSLVIKNLQRVVPIRRVPLRRKMDLVRSILGVKKFDLGIICVDNKTIQNINRIYRNKNVPTDVLSFSFHENLKAGEFPQPHSPDDYNLGDIFLGVEYILQHCRESEDYCDVLTVTATHGLCHLLGFTHSSKAEWQKMYNQEKLVLEELSRYTGARLQPLSRGLY---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A815-1", "uniprot_id": "D4A815_RAT", "id": "D4A815-1", "name": "Endoribonuclease YbeY", "aln": "MSLVIKNLQRVVPIRRMPLRRKMDLVRSILGVKKFDLGIICVDNKNIQNINRIYRNKNVPTDVLSFPFHENLKAGEFPQPRSPDDYNLGDVFLGVEYIFQYCKGNEDYYDVLTVTATHGLCHLLGFTHSSEAEWQKMYNQEKLVLEELSRHTGARLQPLSRGLY---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P58557-1", "uniprot_id": "YBEY_HUMAN", "id": "P58557-1", "name": "Endoribonuclease YbeY", "aln": "MSLVIRNLQRVIPIRRAPLRSKIEIVRRILGVQKFDLGIICVDNKNIQHINRIYRDRNVPTDVLSFPFHEHLKAGEFPQPDFPDDYNLGDIFLGVEYIFHQCKENEDYNDVLTVTATHGLCHLLGFTHGTEAEWQQMFQKEKAVLDELGRRTGTRLQPLTRGLFGGS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****:*****:**** *** *:::** ****:************.**:******::*********.***:********* ********:*******:: *: .*** *******************.::****:*:::** **:**.* **:*****:***: ", "identical_positions": 125, "similar_positions": 29, "identity": "74.85%" }, { "cls_id": "homologset.agr.RGD:1308723", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "B1WC05-1", "uniprot_id": "B1WC05_RAT", "id": "B1WC05-1", "name": "Box C/D snoRNA protein 1", "aln": "MEFAAEKEGTPGGGPQRVAEGARPRPAAGGEGAGDLGGSPEADDGEERNGLTGIKTTED--------AEEIKMDLAVVKQEVVDWSDLDGDISDSHWVKQEVEGGPEVKAE-KDVLEVKQEADSSLVVKEEEVDEPEVKEEKVKVKEEVTDWEEAKEE--DLNVKQ-ELFVGQNVKEEQVMDRVPVKEEDCFKREVTEDTKVKEEPQMNPRVGCKRKLAMSRCETCGTEEAKYRCPRCMRYSCSLPCVKRHKAELMCSG-VRDKTAYVSLQRFTEMN---------LLSDYRFLEDVARTADRVSRDIFLTRPKRK-----KYLLFLKN---------------RARKQGVYLRLLPSGFSKRRENSTVFDHRNQQFCWHVKLQFPQSQAEYVEKRVPDDKTINEILKPYIDPEKSDPVIRQRLKAYTQS---------QTGVQILMRVENMQQNLIRYYELDPSKSLVNNLRNKVIIEYPTLHVVLKGCSNDMQLLHQVKSESAQKLGNGD---------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UFB2-1", "uniprot_id": "BCD1_MOUSE", "id": "Q3UFB2-1", "name": "Box C/D snoRNA protein 1", "aln": "MESAAEKEGTPGGGSQRVAEGARPRPAAGGEGARDLDGSPEAGDGEERNGLAGTKTTED--------AEEIKMDLAVVKQEVVDWSDLDSGVADSQWVKQEVEGGPEVKDE-KGVLEVKQEADSSLVVKEEEVDEPEVKEEKVKVKEEVTDWEEVKEE--DLTIKQ-ELFVGQNVKEEQVMDAAPIKEEGSLKSEAMEDAKVKEEPQMNPRVGSKRKLALSRCETCGTEEAKYRCPRCMRFSCSLPCVKKHKADLTCSG-VRDKTAYVSLQQFTEMN---------LLSDYRFLEDVARTADKVSRDTFLKRPKRK-----KYLFFMKN---------------RARKQGIYLRLLPNGFSKRKENSTVFDHRKQQFCWHVKLQFPQSQAEYIEKRVPDDKTINEILKPYIDPEESDPVIRQRLKAYAQS---------QTGVQILMRVENMQQNMIRYHELDPYKSLSDNLKDKVIIEYPTLHVVLRGSSNDKQLL-QVKSESAQKLGNGN---------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NWK9-1", "uniprot_id": "BCD1_HUMAN", "id": "Q9NWK9-1", "name": "Box C/D snoRNA protein 1", "aln": "MEFAAENEGKSGGGLHSVAEGVRLSPEPGREGVRDLAGAEEFGGGEEGTGLTGIKEIGDGEEGSGQRPEEIPMDLTVVKQEIIDWPGTEGRLAG-QWVEQEVEDRPEVKDENAGVLEVKQETDSSLVVKEAKVGEPEVKEE--KVKEEVMDWSEVKEEKDNLEIKQEEKFVGQCIKEELMHGECVKEEKDFLKKEIVDDTKVKEEPPINHPVGCKRKLAMSRCETCGTEEAKYRCPRCMRYSCSLPCVKKHKAELTCNG-VRDKTAYISIQQFTEMN---------LLSDYRFLEDVARTADHISRDAFLKRPISN-----KYMYFMKN---------------RARRQGINLKLLPNGFTKRKENSTFFDKKKQQFCWHVKLQFPQSQAEYIEKRVPDDKTINEILKPYIDPEKSDPVIRQRLKAYIRS---------QTGVQILMKIEYMQQNLVRYYELDPYKSLLDNLRNKVIIEYPTLHVVLKGSNNDMKVLHQVKSESTKNVGNEN---------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TIB7-1", "uniprot_id": "A0AB32TIB7_DANRE", "id": "A0AB32TIB7-1", "name": "Box C/D snoRNA protein 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKMNLPDVDNNTADEERRAVKRKMAMSRCDVCDCEEAKYRCPSCKKHTCSLVCVKRHKSVSGCSG-VRDQTAFVSLSDFREIH---------MLSDYRFLEDSARLRQQSSRDTVMTSGRQHP----KQGQWMIR---------------KAKAVKVTLKLLPKVFSKHRENTTVFIHRERRFHWHLNIHFPQSEAVYSERR-PDNTPLEQILHGYIHPSEADPVRRQKLKLYVSS---------QQNIRVFLKAELEQLNSLRYHELELNKTLQENLMYKTIIEYPELFVVLDQHSQQYHTPEPDAPDEGTASASSSPSETPAKKKPRVSEDEDLEDGELRSEDDEENQHHTQNKLAEDAERTAGPPEEEHKPSGESERAHDDDDDDDEGQTDRPRPS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P38772-1", "uniprot_id": "BCD1_YEAST", "id": "P38772-1", "name": "Box C/D snoRNA protein 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAVLCGVCGIKEFKYKCPRCLVQTCSLECSKKHKTRDNCSGQTHDPKEYISSEALKQADDDKHERNAYVQRDYNYLTQLKRMVHVQKMDARMKNKRVLGPVGGHNSNFKKRRYDIDEDDRDSTECQRIIRRGVNCLMLPKGMQRSSQNRSKWDKTMDLFVWSVEWILCPMQEKGEKKELFKHVSHRIKETDFLVQGMGKNVFQKCCEFYRLAGTSSCIEGEDGSETKEERTQILQKSGLKFYTKTFPYNTTHIMDSKKLVELAIHEKCIGELLKNTTVIEFPTIFVAMTEADLPEGYEVLHQEPRPLEHTSTLNKFIDNAREEEDAE-------EDSQPTEEPVQKETQDASDSDSDSDDDYNPGLSMDFLTA--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .*. :* **:** * :*** * *:**: *.* .:* . ::* . : : . : **.:* : * . . * :. : : . : : :**. : : :* : : : * * :: : : ::. .. . . :: .. * :: : * : : . : : * . :::: . . : * ::* . : :: .. ", "identical_positions": 34, "similar_positions": 77, "identity": "5.73%" }, { "cls_id": "homologset.agr.RGD:1308725", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4A392-1", "uniprot_id": "D4A392_RAT", "id": "D4A392-1", "name": "", "aln": "--------------------------------------------------------------------MNTLSEANGTFAIHLFKILCQDNPS---------------------------------------KNVCYSPVSISSALAMVLLGAKGDTAVQISQALNLNK---HPDEDIHKDFQLLLHNLNK--------------------PKS-HYCLRIAN-------RLFAENTCKLVPTYKESCLRFYNSEIEQLSFAKAAEESRKHINTWVSKQTEGKIPELLSSDSVGSETKLIMVNALYFQGSWLHCFDKEFTMEMPFKINKK--ETK-PVQMMWQEETFDVAY-VKEIQAQILVMPYRGME-MSFMVLLP----DEGVDIRKVESS--LTFEKLTAWTKPEFIYSTEVYVYLPKFQLQEQYDMTALFQHLGMIDVFSEIK--ADLSGMCPEK--------------------------DLCVSKFVHECVVEVNEEGTEAAAASAADFTVVEYTP---TFCADRPFLFFIRHNQTNSILFCGRFSSP----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F6V5V4-1", "uniprot_id": "F6V5V4_MOUSE", "id": "F6V5V4-1", "name": "", "aln": "--------------------------------------------------------------------MNTLSQANGTFAIHLLKVLCQDNPS---------------------------------------KNVCYSPMSISSALAMVLLGAKGDTAVQICQALHLN-----PDEDVHQGFQLLLHNLNK--------------------QNNQKYCLTMAN-------RLFVENTCELLPTFKESCLKFYHSEMEQLSFAEAAEESRQHINMWVSKQTNGKIPDLLSKDSVNSQTRLILANALYFHGTWCKRFEKNRTKEMPFKINKK--ETR-PVQMMWREDTLFHAY-VKEIQAQVLVMPYEGID-LNFVVLLP----DEGVDISKVENN--LTFEKLTAWTKPEFMNRTEFHVYYPKFQLQEDYDMNSLLQHLGILNVFDGSK--ADLSGMSTKE--------------------------NLCLSEFVHKCVVEVNEEGTEAAAASAVEFIFLCSGPDPETFCADHPFLFFIMHSTTNSILFCGRFSSP----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P50453-1", "uniprot_id": "SPB9_HUMAN", "id": "P50453-1", "name": "Serpin B9", "aln": "--------------------------------------------------------------------METLSNASGTFAIRLLKILCQDNPS---------------------------------------HNVFCSPVSISSALAMVLLGAKGNTATQMAQALSLN-----TEEDIHRAFQSLLTEVNK--------------------AGT-QYLLRTAN-------RLFGEKTCQFLSTFKESCLQFYHAELKELSFIRAAEESRKHINTWVSKKTEGKIEELLPGSSIDAETRLVLVNAIYFKGKWNEPFDETYTREMPFKINQE--EQR-PVQMMYQEATFKLAH-VGEVRAQLLELPYARKE-LSLLVLLP----DDGVELSTVEKS--LTFEKLTAWTKPDCMKSTEVEVLLPKFKLQEDYDMESVLRHLGIVDAFQQGK--ADLSAMSAER--------------------------DLCLSKFVHKSFVEVNEEGTEAAAASSCFVVAECCMESGPRFCADHPFLFFIRHNRANSILFCGRFSSP----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R9A9-1", "uniprot_id": "F1R9A9_DANRE", "id": "F1R9A9-1", "name": "Leukocyte elastase inhibitor", "aln": "--------------------------------------------------------------------MESLSAANTQFSLNLFKKISGGNAS---------------------------------------GNVFYSPVSISSALAMVSLGAKGNTADQMFKVLGFNSQAHQPVEQIHSNFKKFMSELNK--------------------PEA-PYVLSLAN-------RLYGEQTYQLIEKFLNDTKRYYDAGLEKVDFINKSEDARVNINTWVEKNTQEKIKDLLPSGAIDAMTRLVLVNAIYFKGNWEEKFPKEATRDGVFRLNKN--QTK-PVKMMHQKAEFPSGY-IEEMKSHVLELPYAGKN-LSMLIILPDEIEDETTGLQKLERA--LTYEKLMEWTKPEVMHQREVQVSLPKFKTEQTYDMKSLLVSMGMEDVFDPQK--VNLTGMSSSN--------------------------DLVLSKAIHKAFVEVNEEGTEAAAATAAIEKLMCYIP-PLSFNADHPFLFFIRHNPTKSILFYGRLCSP----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VWB4-1", "uniprot_id": "Q9VWB4_DROME", "id": "Q9VWB4-1", "name": "", "aln": "--------------------------------------------------------------------MKLGFLGLFGMVL----------------------------------------------------------------MIMFYEGAEGYTVNELRDVLGIYVD--YPTLRRWYEDVRAYHYLNS--------------------ENTKLFSLRYAYYDDVGDLELVKGYNSVVLEGVGEGNVVLREGRPRGVDFDQG---ASIIINDDIDKASHAKIFSSYSRRSFNSTVTVLGITVSYFKAKWKYPFDKSQTKVEQFYNDGG--SPAGKVEMMVQTGKYAYVNNVKGLQADVLELPFGEHE-LVMIVLLPKSSQGVNLVLYQLKN---LGLHRLLEKLEAS-KNETDVEVKLPKFDTRSVLSLEDTVYDAGLTDLRNDFADLDKLLIAIGHR--------------------------GACLTLYHQFARIVVDEEGLPNAVP------QKSSGKNNIKFHVNRPFAYLVLQKKHKLLIHSGVFREGEIQ-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VPH9-1", "uniprot_id": "Q9VPH9_DROME", "id": "Q9VPH9-1", "name": "", "aln": "--------------------------------------------------------------------MKLGFLGLFGMVLSLRAHICANTVDTKSLLQKMTD----------ARLQFALNLLQMESTHLNLENFAMTPFSTWSLMIMFYEGAEGTTLKQIRDVLAIYVD--YPTLRRWYEDVRAYHYLNS--------------------ENTKLFSLRYAYYDDVGDLELVKGYNSVVLEGVGEGNVVLREGRPRGVDFDQG---ASIIINDDIDKASHAKIFSSYSRRSFNSTVTVLGITVSYFKAKWKYPFDKSQTKVEQFYNAGG--SPAGKVEMMVQTGKYAYVNNVKGLQADVLELPFGEHE-LVMIVILPKPSQRVSLVLKQLKN---LGLHRLLEELEAS-KNESDVEVKLPKFDTRSVLSLEDTVYEAGLTDLRNEFADLGRMLIPTGDR--------------------------GAYLSLYHQFARIVVDEEGLPNAVP------QKSSGTNNIKFHINRPFAYLVLQRTHKLLIHSGVFREGEIQ-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q0E8C8-1", "uniprot_id": "SP77B_DROME", "id": "Q0E8C8-1", "name": "Serine protease inhibitor 77Ba", "aln": "MGKIADCLMLWIPLLLGAIFLCSADPQNNQAPLQLSVGNPLTAFTAPTAFQSGVSHIQSMRSNFDTDVLVSISQGVQDFALDLLQRISVEVEKAN-------------------------------------KDFMISPFSVWSLLVLLYEGSEGETRNQLKKSLRINVE----DEKLRGAYKVWSSFLNI--------------------TTSTIEVATLQA--------IYTGKGYPIKNNYR-DAIQNYNVQPMEVDFYSP--DSVIQINEDTNRTTRGLIPYTILPQDVYG-AKMFLLSSLYFKGQWKFPFNKTLTREEPFFSESG--EVIGKIPMMVQEANFAYVSNVEGLDGYVLELPYGTQDRLAMIVVLPKRGFKLNDVANNLKALGLRPILQRLAAFRNRASEDNEVEVMMPKFVTATDFTLKGVLIQMGIRDLFDENT--ANLDRMSS----------------------------GLFAKLVVHSTKIIVDEQGTTAGAVTEAALANKATPP---KFLLNRPFQYMIVEKATGLLLFAGQVRNPKAA-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VLU4-1", "uniprot_id": "SP28D_DROME", "id": "Q9VLU4-1", "name": "Serine protease inhibitor 28Dc", "aln": "------MWRLLLALLLVSSVCCESELFRDDLRTPETMAYINGLMQRRHQMQQEAQQHIQAIPPAVPLQSPGLVNGLGNQNDPALNRISGTSVKPSNLPAAYSNGYVDLATSDRIANSVLNFANILGQHLANGKTQIYSPLSIVHSLALLLLGAKGRSYEELSTVFDIP-----DTSRLHEQFGLMLQDLQQPTREAISAGRPLTDWRASSAMRSNRRAQRPGAHEVHLANGLFTQTGYTLNPDYRRVIVEVYASDLQIQDFEGSPATARYNINAYVAQHTKNHIENIIAS-DIPQTTRMILANALYFKAFWETDFIESATRPDNFYPNGEGTEPVMRVQMMATGGAYPYHE-DHELGCKIIGLPYRGNL-STMYIIQP--FKSSVRELMALQKR----LTADKIESMISRMYRRAALVAFPKMHLTESVNLKTVMQRMGLGGIFSAVQNDLSLIATNEATRTNALGGNSLQNLEAQRRAGTGGARSDLVVDDIVHKVDFTVNEQGTEAAASS---VTYLKKSGPDVLFRGDTPFMVLVRHDPTKLVLFYGLINEPPAAA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : :. *::* : :: : : :: : . .* : ** : :. * . . :. . **:. * * : * * . : ** : :: :*: : :: * :: * **: : . *: . . : . : . *:*:* .. * : ** :: . ::. * . . ", "identical_positions": 27, "similar_positions": 63, "identity": "4.83%" }, { "cls_id": "homologset.agr.RGD:1308728", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6ATT3-1", "uniprot_id": "A0A8I6ATT3_RAT", "id": "A0A8I6ATT3-1", "name": "Metal transporter", "aln": "MAAAAAAAAALGVRLRDCCSRGAVLLLFFSLSPRPPAAAAWLLGLRPEDTAGGRVSLEGGTLRAAEGTSFLLRVYFQPGPAVPAAPVPAPSLAPGENGTGDWAPRLVFIEEPPGAGSAAPSAVPTRPPGPQRCREQSDWASDVEVLGPLRPGGVAGSALVQVRVRELRKGEAERGGAGGGGKLFSLCAWDGRAWHHHGAAGGFLLRVRPRLYGPGGDLLPPAWLRALGALLLLALSALFSGLRLSLLSLDPVELRVLRNSGSAAEQEQARRVQAVRGRG-THLLCTLLLGQAGANAALAGWLYASLPPGVGDPGEDSGEAGVHFPWLPALVCTGAVFLGAEICPYSVCSRHGLAIASHSVCLTRLLMAAAFPVCYPLGRLLDWALRQEISTFYTRE--KLLETLRAADPYSDLVKEELNIIQGALELRTKVVEEVLTPLGDCFMLRSDAVLDFATVSEILRSGYTRIPVYEGDQRHNIVDILFVKDLAFVDPDDCTPLLTVTRFYNRPLHCVFNDTRLDTVLEEFKKGKS-HLAIVQRVNNEGEGDPFYEVMGIVTLEDIIEEIIKSEILDETDLYTDNRKKQRVPHRERRRHDFSLFKLSDSEIRVKISPQLLLATHRFMATEVEPFKSLYLSEKILLRLLKHPNVIQELKFDERNKKAPEHYLYQRSRPVDYFVLLLQGKVEVEVG--KEGLRFENGAFTYYGVPAIMTSACSDNDVRKVGSLAGSSVFLNRSPSRCSGLNRSESPNRERSDFGGSNTQLCS--NNLYTPDYSVHILSDVQFVKITRQQYQNALTACHMDSSPQSPDMEAFTDGDSTKAPTTRGTPQTPKDDPVLTLLSNRTSLPCSRSDGLRSPGEVVYLRMEEMAFPQEEMPNFEEHKAQQVSLSPVTVPTAAASETECCNIHLDPEASPCSSDSEETMGKKLLRTLSGRKRKKSADGERASEENSNLTPLIT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q0GA42-1", "uniprot_id": "CNNM1_MOUSE", "id": "Q0GA42-1", "name": "Metal transporter CNNM1", "aln": "MAAAAAAAAALGVRLRDCCSRGAVLLLFFSLSPRPPAAAAWLLGLRPEDTAGGRVSLEGGTLRAAEGTSFLLRVYFQPGPPVPAAPVPAPSLAPGENGTGDWAPRLVFIEEPPGAGGAAPSAVPTRPPGPQRCREQSDWASDVEVLGPLRPGGVAGSALVQVRVRELRKGEAERGGAGGGGKLFSLCAWDGRAWHHHGAAGGFLLRVRPRLYGPGGDLLPPAWLRALGALLLLALSALFSGLRLSLLSLDPVELRVLRNSGSAAEQEQARRVQAVRGRG-THLLCTLLLGQAGANAALAGWLYASLPPGVGDPGEDSGEAGVHFPWLPALVCTGAVFLGAEICPYSVCSRHGLAIASHSVCLTRLLMAAAFPVCYPLGRLLDWALRQEISTFYTRE--KLLETLRAADPYSDLVKEELNIIQGALELRTKVVEEVLTPLGDCFMLRSDAVLDFATVSEILRSGYTRIPVYEGDQRHNIVDILFVKDLAFVDPDDCTPLLTVTRFYNRPLHCVFNDTRLDTVLEEFKKGKS-HLAIVQRVNNEGEGDPFYEVMGIVTLEDIIEEIIKSEILDETDLYTDNRKKQRVPHRERRRHDFSLFKLSDSEIRVKISPQLLLATHRFMATEVEPFKSLYLSEKILLRLLKHPNVIQELKFDERNKKAPEHYLYQRNRPVDYFVLLLQGKVEVEVG--KEGLRFENGAFTYYGVPAIMTSACSDNDVRKVGSLAGSSVFLNRSPSRCSGLNRSESPNRERSDFGGSNTQLYSSSNNLYTPDYSVHILSDVQFVKITRQQYQNALTACHMDSSPQSPDMEAFTDGDSTKAPTTRGTPQTPKDDPVLTLLSNRTSLPCSRSDGLRSPGEVVYLRMEEMAFPQEEMPNFEEHRSQQVSLSPVAVPTTAASDPECCNIHLDPEASPCSSDSEENMGKKLLRTLSGRKRKKSADGERASEENSNLTPLIT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NRU3-1", "uniprot_id": "CNNM1_HUMAN", "id": "Q9NRU3-1", "name": "Metal transporter CNNM1", "aln": "MAAAAAAAAAVGVRLRDCCSRGAVLLLFFSLSPRPPAAAAWLLGLRPEDTAGGRVSLEGGTLRAAEGTSFLLRVYFQPGPPATAAPVPSPTLNSGENGTGDWAPRLVFIEEPPGGGGVAPSAVPTRPPGPQRCREQSDWASDVEVLGPLRPGGVAGSALVQVRVRELRKGEAERGGAGGGGKLFSLCAWDGRAWHHHGAAGGFLLRVRPRLYGPGGDLLPPAWLRALGALLLLALSALFSGLRLSLLSLDPVELRVLRNSGSAAEQEQARRVQAVRGRG-THLLCTLLLGQAGANAALAGWLYTSLPPGFGGTGEDYSEEGIHFPWLPALVCTGAVFLGAEICPYSVCSRHGLAIASHSVCLTRLLMAAAFPVCYPLGRLLDWALRQEISTFYTRE--KLLETLRAADPYSDLVKEELNIIQGALELRTKVVEEVLTPLGDCFMLRSDAVLDFATVSEILRSGYTRIPVYEGDQRHNIVDILFVKDLAFVDPDDCTPLLTVTRFYNRPLHCVFNDTRLDTVLEEFKKGKS-HLAIVQRVNNEGEGDPFYEVMGIVTLEDIIEEIIKSEILDETDLYTDNRKKQRVPQRERKRHDFSLFKLSDTEMRVKISPQLLLATHRFMATEVEPFKSLYLSEKILLRLLKHPNVIQELKFDEKNKKAPEHYLYQRNRPVDYFVLLLQGKVEVEVG--KEGLRFENGAFTYYGVPAIMTTACSDNDVRKVGSLAGSSVFLNRSPSRCSGLNRSESPNRERSDFGGSNTQLYSSSNNLYMPDYSVHILSDVQFVKITRQQYQNALTACHMDSSPQSPDMEAFTDGDSTKAPTTRGTPQTPKDDPAITLLNNRNSLPCSRSDGLRSPSEVVYLRMEELAFTQEEMTDFEEHSTQQLTLSPAAVPTRAASDSECCNINLDTETSPCSSDFEENVGKKLLRTLSGQKRKRSPEGERTSEDNSNLTPLIT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B7P9G0-1", "uniprot_id": "UEX_DROME", "id": "A0A0B7P9G0-1", "name": "Unextended protein", "aln": "--------------MNTYFISFITIIIFANGINGTSVDTSNKLLLQKANDFNLSQNLSSSRTRRTIANSFRIVGIRLEDETVETKNGIPTVLVDKEQQFRVFGSGLEENTAITFTNEKNDYGGPCLKPATDLFTPIEVSSNGFSALYSVKFPSFINEFFICAKTAEKTTNHSKAATT--------------TPLEHQGNSD----FLKIKTFEP----LIPVWLAIIIIVTCLGFSALFSGLNLGLMSMDRTELKILRNTGTEKEKKYASKIAPVRDQG-NYLLCSILLGNVLVNSTFT-ILLDGLTSG----------------LFAVIFSTLAIVLFGEITPQAVCSRHGLAIGAKTILVTKTVMAITAPLSYPVSRILDKLLGEEIGNVYNRE--RLKELVRVTNDVNDLDKNEVNIISGALELRKKTVADVMTHINDAFMLSLDALLDFETVSEIMNSGYSRIPVYDGD-RKNIVTLLYIKDLAFVDTDDNTPLKTLCEFYQNPVHFVFEDYTLDIMFNQFKEGTIGHIAFVHRVNNEGDGDPFYETVGLVTLEDVIEELIQAEIVDETDVFVDNRTKTRR--NRYKKADFSAFAERREVQTVRISPQLTLATFQYLSTAVDAFKKDVISELILRRLLN-QDVFHNIKTKGKSKDDPSLYIFTQGKAVDFFVLILEGRVEVTIG--KEALMFESGPFTYFGTQALVPNVVIDS------------------PTQMGSLQSLNMDSKIR---------------QSFVPDYSVRAISDVIYITIKRVLYLTAKKATLLEKSRKSGTFSSETFDDEVERLLHS---ITENEKPSCFAQNQSTRRLSNRS---INSSPTNMNRSPDFVYNSVDEAIQDDTKLKNIKHADNVTTSISLVAAELEDLHSGEQDTTAAS-------MPLLPKLDDKFESKQSKP---------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12296-1", "uniprot_id": "MAM3_YEAST", "id": "Q12296-1", "name": "Protein MAM3", "aln": "------------------------------------------------------MSFLPLRSRSRSGAPHWVYIILYHIFTIPKIYSLP------------------------------------LLSGSHVLNSRDVADSGHSVGDEASVTTYY-----------------------------------------------------------------------IISIILVLLGGVFAGLTLGLMGQDEVYLKVISTSGSNSEKKLAKRVLDLISRGKHWVLVTLLLSNVITNETLPIVLDRCLGGG----------------WQAVVSSTILIVIFGEIIPQSVCVKYGLQVGAFFCPFVLVLMYLMYPVAYPIATLLDYMLGEDHGTMYKKSGLKTLVTLHRTMGVERLTKDEVTIISAVLDLKAKRVEEIMTPIENVFTMSADTILDDKTVEKIFNSGFSRIPIFLPNEPNNFIGMLLVRVLISYDPDDCLPIS---HFPLATLPETSPNTSCLNILNYFQEGKA-HMCVVSKEPGSSHG-----AIGVLTLEDVIEELIGEEIVDESDVFVDMHQHIMR-------------QQPGPLSKRHITSYLHHLYTSSHKEHKAADQADESSPLLSPSNSNHPSEHPQQDLNNKSWKQKSNDGYDRSNAVLSPTPQVTEHGTIIPSNLASNPLNVNKSFVTIKKPANVPKIITTHTPHS-----------SKEPSPAPHSNDKSLSAEEQ----------------QLLSDHAELSRQAVLHTQRSGQPTQVTTSTKTTRNSPDSISIPNSGANHGNENQNVTISTSYQNTKN-----GIVESVITVKGVPKTIIGPAKDWDESKSEYGNENINQENSNRSDDRESSSSNASLFSSIKNKFKNENANNNDRSNFT-------DSLSRTSNYDANGSSSTIKR-------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: * . .. : . . .... . .. .. : : : :..:*:** *.*:. * . *::: .:*: *:: * :: : .:* :* ::**.:. .* ::. * * * ..: .* :.: .** * :** ::** :.: .. :* *:.**:. :** * :: ...*.:. : :: : . * *:*:.**...*:*: * * :::* : : * : *::** **.:*:.**::***:: : :*:: :* :: * *.** *: .* .: . : ::: *::*. *:..* : ....* .:*::****:***:* **:**:*::.* : : :*:. * . : * : : . : . . :. . . : :...* . : : : . . . .*. * :.. *: : . . : .*:: . * . . : .: .* .* : .. : : . . :. . . . : . : :. .: : .. : : : : . : . : * . . . .. ", "identical_positions": 97, "similar_positions": 235, "identity": "10.14%" }, { "cls_id": "homologset.agr.RGD:1308729", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "B8JJZ9-1", "uniprot_id": "B8JJZ9_MOUSE", "id": "B8JJZ9-1", "name": "", "aln": "MDCLTFEDVAVNFTLEEWDLLDPSQKQLYTDVMQETFKNLIAIGQIEEVQRSKDVDEDSRRNLRRGLVELLYKPSEGRQCDGIFSEFPDTVMNKKTSHGVKRCESNLCEDILIGLPPLNMHIPLQPGHKRYEYEVYEDSLYKFRECGKTFMYPECYLKHGNTHTIEKPYKCHQCGKAFSSSSKVRRHERTHTGEKPYICNHCGKAFPSRGSLRRHDRIHSGEKPFVCKYCGKAFTGQSSLPRHERIHSGEKPYVCKYCGKCFISSSTCRVHERTHTGEKLYVCNLCNKAVTTRTSLRNHERIHSGEKPYVCEQCGKGFISSGTFRIHERIHTGEKPYRCKECGKAFTIQSSLQRHERIHTREKPYDCKECGKAFSGYSSLRRHERIHSGERPYACKQCGKAFPALGDCQRHEQIHTGEKPYICKQCGKAFTRCGSLRIHEKTHARENS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LTF2-1", "uniprot_id": "A0ABK0LTF2_RAT", "id": "A0ABK0LTF2-1", "name": "", "aln": "MDCLTFEDVAVNFTLEEWDLLDPSQKQLYTDVMQETFKNLIAIGQIEEGRRSKDDDEESRRSLRSGLVELLCKPRESRQCEEIFSEFPDTVVNKKTPHGVKLCESHLCEDILIGLPPLNMHIPVQRGHRPYEYETYEDSLYKFRECGKAFLYSECYLKHENAHIIEKPYKCQQCGKAFSSSSKVRRHERTHTGEKPYMCNHCGKAFPSRGSLRRHDRIHSGEKPFVCKYCGKAFTGQSSLPRHERIHSGEKPYVCKYCGKCFISSSTCRVHERTHTGEKLYVCNLCNKAVTTRTSLRNHERIHSGEKPYVCEQCGKGFISSGTFRIHERIHTGEKPYRCKECGKAFTIQSSLQRHERIHTREKPYDCKECGKAFSGYSSLRRHERIHSGERPYACKQCGKAFPALGDCQRHEQIHTGEKPYICKQCGKAFTRCGSLRIHEKTHARQNS", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "************************************************ :**** **:***.** ****** ** *.***: *********:****.**** ***:*****************:* **: ****.*************:*:*.****** *:* *******:*************************:*******************************************************************************************************************************************************************************************************************************************************:**", "identical_positions": 419, "similar_positions": 18, "identity": "93.53%" }, { "cls_id": "homologset.agr.RGD:1308730", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P57748-1", "uniprot_id": "MMP20_MOUSE", "id": "P57748-1", "name": "Matrix metalloproteinase-20", "aln": "MKVLPASGLAV-LVTALKFATADPNLLAATPRTFRSNYHLAQAYLDKYYTKKGGPQAGEMVARESNPMIRRIKELQIFFGLKVTGKLDQNTMNVIKKPRCGVPDVANYRLFPGEPKWKKNILTYRISKYTPSMSPTEVDKAIQMALHAWSTAVPLNFVRINSGEADIMISFETGDHGDSYPFDGPRGTLAHAFAPGEGLGGDTHFDNAEKWTMGTNGFNLFTVAAHEFGHALGLGHSTDPSALMYPTYKYQNPYRFHLPKDDVKGIQALYGPRKIFPGKPTMPHIPPHKPSIPDLCDSSSSFDAVTMLGKELLFFKDRIFWRRQVHLPTGIRPSTITSSFPQLMSNVDAAYEVAERGIAFFFKGPHYWVTRGFHMQGPPRTIYDFGFPRHVQRIDAAVYLKEPQKTLFFVGEEYYSYDERKKKMEKDYPKNTEEEFSGVSGHIDAAVELNGYIYFFSGRKTFKYDTEKEDVVSVVKSSSWIGC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZXD9-1", "uniprot_id": "D3ZXD9_RAT", "id": "D3ZXD9-1", "name": "", "aln": "MKVLPASGLAV-LVTALKFATAAPALLAATPRTFRSNYHLAQAYLDKYYTKKGGPQAGEMVARESNPTVRKIKELQTFFGLRVTGKLDQNTMDVIKRPRCGVPDVANYRLFPGEPKWKKNILTYRVSKYTPSMSPTEVDKAVHMALHAWSTAVPLIFVRINSGEADIMISFETGDHGDSYPFDGPRGTLAHAFAPGEGLGGDTHFDNAEKWTMGTNGFNLFTVAAHEFGHALGLGHSTDPSALMYPTYKYQNPYRFHLPKDDVKGIQALYGPRKTFPGKPTMPHIPPHKPSIPDLCDSSSSFDAVTMLGKELLFFKDRIFWRRRVHLPAGIRPSTITSSFPQLMSNVDAAYEVAERGIAFFFKGPHYWVTRGFQMQGPPRTIYDFGFPRHVQRIDAAVYLKEPQKTLFFVGEEYYSYDERKKKMEKDYPKSTEEEFSGVSGHIDAAVELNGYIYFFSGPKTFKYDTEKEDVVSVVKSSSWVGC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O60882-1", "uniprot_id": "MMP20_HUMAN", "id": "O60882-1", "name": "Matrix metalloproteinase-20", "aln": "MKVLPASGLAVFLIMALKFSTAAPSLVAASPRTWRNNYRLAQAYLDKYYTNKEGHQIGEMVARGSNSMIRKIKELQAFFGLQVTGKLDQTTMNVIKKPRCGVPDVANYRLFPGEPKWKKNTLTYRISKYTPSMSSVEVDKAVEMALQAWSSAVPLSFVRINSGEADIMISFENGDHGDSYPFDGPRGTLAHAFAPGEGLGGDTHFDNAEKWTMGTNGFNLFTVAAHEFGHALGLAHSTDPSALMYPTYKYKNPYGFHLPKDDVKGIQALYGPRKVFLGKPTLPHAPHHKPSIPDLCDSSSSFDAVTMLGKELLLFKDRIFWRRQVHLRTGIRPSTITSSFPQLMSNVDAAYEVAERGTAYFFKGPHYWITRGFQMQGPPRTIYDFGFPRHVQQIDAAVYLREPQKTLFFVGDEYYSYDERKRKMEKDYPKNTEEEFSGVNGQIDAAVELNGYIYFFSGPKTYKYDTEKEDVVSVVKSSSWIGC", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*********** *: ****:** * *:**:***:*.**:***********:* * * ****** **. :*:***** ****:*******.**:***:*********************** ****:********..*****:.***:***:**** ****************.*************************************************************.***************:*** ******************* * ****:** * **************************:*********:*** :**************************** *:********:****:******************:*******:**********:*********:********.********.*:**************** **:******************:**", "identical_positions": 422, "similar_positions": 41, "identity": "87.37%" }, { "cls_id": "homologset.agr.RGD:1308731", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZGJ3-1", "uniprot_id": "D3ZGJ3_RAT", "id": "D3ZGJ3-1", "name": "", "aln": "MTMEKSGNIQLEIPDFSNSVLSHLNQLRMQGRLCDIVVNVQGQAFRAHKVVLAASSPYFRDHMSLNEMSTVSISVIKNPTVFEQLLSFCYTGRICLQLADIISYLTAASFLQMQHIIDKCTQILEGIHFKINVAEVEAELSQTRTKHPERPPESHRVTPNLTRSLSPRHNASKGNWRGQVSAVLDIRELSPPEESTSPQIIEQSSDVEGREPILRINRAGQWYVETGIADQGPQSGDEVRVLGAVHIKTENLEEWLGPENQPSGEDGSSAEEVAAMVIDTTGHGSVGQESYTLGSSGAKVARPTSSEVDRFSPSGSVVSMTERHRARSESPGRMDEPKQLSSQVEESAMMGVSAYVEYLREQEVSERWFRYNPRLTCIYCAKSFNQKGSLDRHMRLHMGITPFVCRMCGKKYTRKDQLEYHIRKHTGNKPFHCHVCGKSFPFQAILNQHFRKNHPGCIPLEGPHSISPETTVTSR-QAEEGSPSHEETVAPGESAQGSVSTTGPD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5TC79-1", "uniprot_id": "ZBT37_HUMAN", "id": "Q5TC79-1", "name": "Zinc finger and BTB domain-containing protein 37", "aln": "--MEKGGNIQLEIPDFSNSVLSHLNQLRMQGRLCDIVVNVQGQAFRAHKVVLAASSPYFRDHMSLNEMSTVSISVIKNPTVFEQLLSFCYTGRICLQLADIISYLTAASFLQMQHIIDKCTQILEGIHFKINVAEVEAELSQTRTKHQERPPESHRVTPNLNRSLSPRHNTPKGNRRGQVSAVLDIRELSPPEESTSPQIIEPSSDVESREPILRINRAGQWYVETGVADRGGRSDDEVRVLGAVHIKTENLEEWLGPENQPSGEDGSSAEEVTAMVIDTTGHGSVGQENYTLGSSGAKVARPTSSEVDRFSPSGSVVPLTERHRARSESPGRMDEPKQPSSQVEESAMMGVSGYVEYLREQEVSERWFRYNPRLTCIYCAKSFNQKGSLDRHMRLHMGITPFVCRMCGKKYTRKDQLEYHIRKHTGNKPFHCHVCGKSFPFQAILNQHFRKNHPGCIPLEGPHSISPETTVTSRGQAEEESPSQEETVAPGEAVQGSVSTTGPD", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***.********************************************************************************************************************************************* *************.********:.*** ************************** *****.******************:**:* :*.*************************************:***************.****************************.:******************* *************.************************************************************************************************************************* **** ***:********:.**********", "identical_positions": 479, "similar_positions": 17, "identity": "94.85%" }, { "cls_id": "homologset.agr.RGD:1308732", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BHG3-1", "uniprot_id": "CC50B_MOUSE", "id": "Q8BHG3-1", "name": "Cell cycle control protein 50B", "aln": "--------------------MTWSATAR--------------------GAHQPDNTAFTQQRLPAWQPLLSAGIALPLFFCAGLAFIGLGLGLFYSSNGIKELEYDYTGNPGTGDCSVCAAK--------------------------GQGRAPPPGCACSWSFTLPELFPGPVYLYYELSNFYQNNRRYGVSRDDAQLSGLASALRHPANECAP---YQFRSD-GLPIAPCGAIANSLFNDSFSLWHQRQPSDPFVEVPLDRTAIAWWTDYHVKFRNPPLVNGSLALAFRGTAPPPNWHRPVYELSPD-PNNTGFINQDFVVWMRTAALPTFRKLYARIRQG--NYSAGLPRGTYRVNITYNYPVRAFGGHKLIILSNISWMGGKNPFLGIAYLVVGSLCIVMGFVMLVVYIRYQDQDDDDNDDE-----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3Z9E9-1", "uniprot_id": "D3Z9E9_RAT", "id": "D3Z9E9-1", "name": "Cell cycle control protein", "aln": "--------------------MTWSASAR--------------------GAQQPDNTAFTQQRLPAWQPLLSAGITLPLFFCAGLAFIGLGLGLFYSSNGIQELEYDYTGNPGTGNCSVCAAK--------------------------GQDRAPPPSCQCSWSFTLPELFPGPVYLYYELSNFYQNNRRYGVSRDDAQLSGLASALRHPANECAP---YQFSSD-GLPIAPCGAIANSLFNDSFSLWHQRQPADPFVEVPLDRTAIAWWTDYHVKFRNPPLVNGSLALAFKGTAPPPNWHRPVYELSPD-PNNTGFINQDFVVWMRTAALPTFRKLYARIRQG--NYSAGLPRGTYRVNITYNYPVRAFGGHKLIILSNISWMGGKNPFLGIAYLVVGSLCILMGFVMLVVYIRYQDQDDDDNDDE-----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3MIR4-1", "uniprot_id": "CC50B_HUMAN", "id": "Q3MIR4-1", "name": "Cell cycle control protein 50B", "aln": "--------------------MTWSATAR--------------------GAHQPDNTAFTQQRLPAWQPLLSASIALPLFFCAGLAFIGLGLGLYYSSNGIKELEYDYTGDPGTGNCSVCAAA--------------------------GQGRALPPPCSCAWYFSLPELFQGPVYLYYELTNFYQNNRRYGVSRDDAQLSGLPSALRHPVNECAP---YQRSAA-GLPIAPCGAIANSLFNDSFSLWHQRQPGGPYVEVPLDRSGIAWWTDYHVKFRNPPLVNGSLALAFQGTAPPPNWRRPVYELSPD-PNNTGFINQDFVVWMRTAALPTFRKLYARIRQG--NYSAGLPRGAYRVNITYNYPVRAFGGHKLLIFSSISWMGGKNPFLGIAYLVVGSLCILTGFVMLVVYIRYQDQDDDDEE-------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VXG0-1", "uniprot_id": "Q9VXG0_DROME", "id": "Q9VXG0-1", "name": "", "aln": "--------------MSTQQAENEESAAA--------------------KSKRPSDSAFKQQRLPAWQPVLTARTVLPTFFVIGVLFIPIGVVLLHLSNTANELIIDYTKCRRSGGNTTCAEY--------------------------LEAN-PGVTCPCEVPFVLPSDFNGVVYMYYGLTNYYQNHRRYVKSRDDEQLLGHLS--QTPSTDCAP---FAYDPDSGKPIAPCGAIANSLFNDTLTLLQGGS------EIKLLKTGIAWPSDKRVKFRNP---EGNLNVSLEGFSKPIFWQKGLADLDPENPDNNGFQNEDLIVWMRTAALPSFRKLYRRLNQTNTNYANGLKSGNYTLNIKYNYPVVSFDGTKRMILSTTSVLGGKNPFLGIAYIVVGAICITLGLALLFIHMRCSRSNMEMINVNPHTQYS-----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53740-1", "uniprot_id": "YN8S_YEAST", "id": "P53740-1", "name": "Phospholipid-transporting ATPase accessory subunit CRF1", "aln": "--------MGLILRWKEKKQLSSKQNAQ--------------------KSRKPANTSFRQQRLKAWQPILSPQSVLPLLILMACVFAPIGIGLVVSTISVQRLVVNYTECDALAPAKHFETIPSEYVDYHFSKKVAV--QPQWMVLTDPE----LGNQTCRIQFEVPNHIKKSTYVYYRLTNFNQNYREYVQSLDLDQLKGK----ALIGNDLDPNCDPLRTVEN-KTIFPCGLIANSMFNDTFGTTLTGVN-DTAD-YLLTTKGIAWDTDSHR--------YGKTEYNASDIVPPPNWAKLFPNGYTDDNIPDLQNWEQFKIWMRTAALPNFYKLAMKNETN------GLGKGIYIADIELNYPVRSFYGTKSFVLTTNSIIGAGNEALGIVYLIVAGIATLFAILFLIKVIFKPRPMHDHSYLNFENSDTP-FDESSVVSIPLREIL", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P25656-1", "uniprot_id": "CDC50_YEAST", "id": "P25656-1", "name": "Phospholipid-transporting ATPase accessory subunit CDC50", "aln": "----------MVSLFKRGKAPPLTKEGP--------------------TSKKPPNTAFRQQRLKAWQPILSPQSVLPLLIFVACIFTPIGIGLIVSATKVQDLTIDYSHCDTKASTTAFEDIPKKYIKYHFKSKVEN--KPQWR-LTENE----NGEQSCELQFEIPNDIKKSIFIYYKITNFYQNHRRYVQSFDTKQILGE----PIKKDDLDTSCSPIRSRED-KIIYPCGLIANSMFNDTFSQVLSGID-DTED-YNLTNKHISWSIDRHR--------FKTTKYNASDIVPPPNWMKKYPDGYTDENLPDIHTWEEFQVWMRTAAFPKFYKLTLKNESA------SLPKGKYQMNIELNYPISLFGGTKSFVLTTNGAIGGRNMSLGVLYLIVAGLCALFGIIFLVKLIFQPRAMGDHTYLNFDDEENEDYEDVHAENTTLREIL", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P42838-1", "uniprot_id": "LEM3_YEAST", "id": "P42838-1", "name": "Phospholipid-transporting ATPase accessory subunit LEM3", "aln": "MVNFDLGQVGEVFRRKDKGAIVSGDNPEEEEDVDASEFEEDEVKPVRTKNRRPKEDAFTQQRLAAINPVLTPRTVLPLYLLIAVVFVIVGGCILAQNSKVDEVTIYYQDCMTNATS-SWSDIPSEHWQFVFHKYKTYNTAPQWRFVDDESDDFTKQRGTCQIRFTTPSDMKNNVYLNYVLEKFAANHRRYVLSFSEDQIRGEDASYETVHDATGINCKPLSKNADGKIYYPCGLIANSMFNDTFPLQLTNVG-DTSNNYSLTNKGINWESDKKR--------YKKTKYNYTQIAPPPYWEKMYPDGYNETNIPDIQDWEEFQNWMRPGAFDKITKLIRINKND------TLPAGEYQLDIGLHWPVLEFNGKKGIYLTHGSHLGGRNPFLGIVYLIGGCICAAMALILLTFWLFGGRKIADASSLSWNMK-------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::* : :* **** * :*:*:. .** : . * :* : . : * . . * * *. : :: * : :: * *.* * . *: * *** ****:***:: * . * * * : . * * : : : ::: ***..*: .: ** . * * * :* ::*: * * * : :: . :*. * **: *:: . :. .: :* : : ", "identical_positions": 60, "similar_positions": 66, "identity": "13.36%" }, { "cls_id": "homologset.agr.RGD:1308733", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EPJ3-1", "uniprot_id": "RT26_RAT", "id": "Q9EPJ3-1", "name": "Small ribosomal subunit protein mS26", "aln": "MLRA----LNR--LAARPGGQPP-TLLLLPVRGRKTRHDPPAKSKVGRVKMPPAVDPAELFVLTERYRQYRETVRALRREFTLEVRGKLHEARAGVLAERKAQEAIREHQELMAWNREENRRLQELRIARLQLEAQAQELRQAEVQAQRAQEEQAWVQLKEQEVLKLQEEAKNFITRENLEARIEEALDSPKSYNWAVTKEGQVVRN--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80ZS3-1", "uniprot_id": "RT26_MOUSE", "id": "Q80ZS3-1", "name": "Small ribosomal subunit protein mS26", "aln": "MLRA----LNR--LAARPETRPP-TPLLLPVRGRKTRHDPPAKSKVGRVQTPPAVDPAEFFVLTERYRQYRETVRALRLEFTLEVRRKLHEARAGVLAERKAQQAITEHRELMAWNRDENRRMQELRIARLQLEAQAQEVQKAEAQAQRAQEEQAWVQLKEQEVLKLQEEAKNFITRENLEARIEEALDSPKSYNWAVTKEGQVVRN--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BYN8-1", "uniprot_id": "RT26_HUMAN", "id": "Q9BYN8-1", "name": "Small ribosomal subunit protein mS26", "aln": "MLRA----LSR--LGAGTPCRPR-APLVLPARGRKTRHDPLAKSKIERVNMPPAVDPAEFFVLMERYQHYRQTVRALRMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLHELRIARLRQEEREQEQRQALEQARKAEEVQAWAQRKEREVLQLQEEVKNFITRENLEARVEAALDSRKNYNWAITREGLVVRPQRRDS---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DH29-1", "uniprot_id": "Q6DH29_DANRE", "id": "Q6DH29-1", "name": "Small ribosomal subunit protein mS26", "aln": "MLRA----LSRCPLPAVRLLAPRSAVLVESVRGRKSRTDPQAKSKIGRIKTPPPVDPVEMITMKERYTEYNLILKALRLEFRENMLRKRYEEEVGSVAEERAKRDAEEHKSLMAWNDAENHRLQVIREQRVQKEAEAAEEKRKEAAMLHQQELENYIKEKERQILQLQEEAKNFITLDNLDQRIEEALDNPINYNFAIDKQGRVVKRTAFQ----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VVN2-1", "uniprot_id": "RT26_DROME", "id": "Q9VVN2-1", "name": "Small ribosomal subunit protein mS26", "aln": "MLRAGCQLLTQSTLPTGKTVGNSFALEFVRWR-RKPRWLPVAKSKMFRVPERKKQSEEERTELMRLHNQYKTQLRSVRQFLREEVVRHEETSTADHIVLT-PEQEEAEFQKCLDANAAWNAAIAKERDQRLAKKREEKVAYIQERLEAQQLREEERKEQANQRVLLEIERSKNYITRENLDAAIETALANPVDHNFAIDMAGNLYHGRSTSQLPDATPEPNQQVLSN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**** *.: * : : . * **.* * ****: *: . * : . : .*. ::::* : :: : .. :. . . *.:. : * * : * *: : . : . : : ::.:* *. **:** :**: :* ** . .:*:*: * : : ", "identical_positions": 38, "similar_positions": 56, "identity": "16.74%" }, { "cls_id": "homologset.agr.RGD:1308734", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U2V4-1", "uniprot_id": "LYLAP_RAT", "id": "Q5U2V4-1", "name": "Lysosomal leucine aminopeptidase", "aln": "--MCHRSHGRSLRPPSPLLLLLPLLLQSPWAAGAAEKHNSAGVHYATAYWLPDT------KAVEIKMVLDKKGDAYGFYNDSIQTTGWGVLEIKAGYGSQILSNEIIMFLAGYLEGYLTALHMYDHFTNLYPQLIKN----PSIVKKVQDFMEKQELWTRKNIKDQKDDPFWRHTGYVVSQLDGMYLGAQK---RASEEEMKPMTMFQIQFLNAVGDLLDLIPSLS---------PTKSSSLKKFKIWEMGHCSALIKVLPGFEN-----IYFAHSSWYTYAAMLRIYKHWDFN------IKDKYTASNRLSFSSYPGFLESLDDFYILSS---GLILLQTTNSVYNKTLLKLVVPESLLAWQR-VRVANMMAQGGKEWSQLFSMYNSGTYNNQYMVLDLKKVTLKKSID-------------------------------RGALYVVEQIPTYVEYSDQTN---ILRKGYWASYNIPFHKTVYNWSGYPLLVHK---LGLDYSYDLAPRAKIFRRDQGTVTDMASMKHIMRYNNYKVDPYSK--------------------GDPCSTICCREDLNEASPSPGGCYDT----------KVADIFLASQYKAYAISGPTVQN---GLPPFNWNRFN----DTLHQGMPDVFDFDFVTMKPILT----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VCI0-1", "uniprot_id": "LYLAP_MOUSE", "id": "Q8VCI0-1", "name": "Lysosomal leucine aminopeptidase", "aln": "--MCHRSPGRSLRPPSPLLLLLPLLLQPPWAAGAASQSDPTGVHCATAYWSPES------KKVEIKTVLDKNGDAYGYYNDSIKTTGWGILEIRAGYGSQVLSNEIIMFLAGYLEGYLTALHMYDHFTNLYPQLFKN----PSIVKKVQDFMEKQEMWTRQNIKAQKDDPFWRHTGYVVTQLDGLYLGAQK---RASEEKIKPMTMFQIQFLNAVGDLLDLIPSLS---------PTKSSSMMKFKIWEMGHCSALIKVLPGFEN-----IYFAHSSWYTYAAMLRIYKHWDFN------IKDKYTLSKRLSFSSYPGFLESLDDFYILSS---GLILLQTTNSVYNKTLLKQVVPKTLLAWQR-VRVANMMAEGGKEWAQIFSKHNSGTYNNQYMVLDLKKVTINRSLD-------------------------------KGTLYIVEQIPTYVEYSDQTN---VLRKGYWASYNIPFHKTIYNWSGYPLLVHK---LGLDYSYDLAPRAKIFRRDQGNVTDMASMKYIMRYNNYKEDPYSK--------------------GDPCSTICCREDLNGASPSPGGCYDT----------KVADIFLASQYKAYAISGPTVQD---GLPPFNWNRFN----DTLHRGMPEVFDFNFVTMKPILS----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6P4A8-1", "uniprot_id": "LYLAP_HUMAN", "id": "Q6P4A8-1", "name": "Lysosomal leucine aminopeptidase", "aln": "--MTRGGPGGRPGLPQPPPLLLLLLLLP-LLLVTAEPPKPAGVYYATAYWMPAE------KTVQVKNVMDKNGDAYGFYNNSVKTTGWGILEIRAGYGSQTLSNEIIMFVAGFLEGYLTAPHMNDHYTNLYPQLITK----PSIMDKVQDFMEKQDKWTRKNIKEYKTDSFWRHTGYVMAQIDGLYVGAKK---RAILEGTKPMTLFQIQFLNSVGDLLDLIPSLS---------PTKNGSLKVFKRWDMGHCSALIKVLPGFEN-----ILFAHSSWYTYAAMLRIYKHWDFN------VIDKDTSSSRLSFSSYPGFLESLDDFYILSS---GLILLQTTNSVFNKTLLKQVIPETLLSWQR-VRVANMMADSGKRWADIFSKYNSGTYNNQYMVLDLKKVKLNHSLD-------------------------------KGTLYIVEQIPTYVEYSEQTD---VLRKGYWPSYNVPFHEKIYNWSGYPLLVQK---LGLDYSYDLAPRAKIFRRDQGKVTDTASMKYIMRYNNYKKDPYSR--------------------GDPCNTICCREDLNSPNPSPGGCYDT----------KVADIYLASQYTSYAISGPTVQG---GLPVFRWDRFN----KTLHQGMPEVYNFDFITMKPILKLDIK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VRK8-1", "uniprot_id": "PLBL_DROME", "id": "Q9VRK8-1", "name": "Putative phospholipase B-like lamina ancestor", "aln": "MLKVVGASWQKTRIGTYILIGAGLLVIGAFFIGYMERPEYDGTYCATALWTKQVGFQIENWKQQNDLVNIPTGVGRICYKDSVYENGWAQIEVET---QRTYPDWVQAYAAGMLEGSLTWRNIYNQWSNTISSSCERDESTQKFCGWLRDLLTTNYHRLKRQTEKAENDHYWHQLHLFITQLEGLETGYKRGASRARSDLEEEIPFSDFLLMNAAADIQDLKIYYENYELQNSTEHTEEPGTDQPKNFFLPSATMLTKIVQEEESPQVLQLLFGHSTAGSYSSMLRIQKRYKFHYHFSSKLRSNTVPGVDITFTGYPGILGSTDDFYTIKGRHLHAIVGGVGIKNENLQLWKTVDPKKMVPLVARVMAANRISQNRQTWASAMSRHP-FTGAKQWITVDLNKMKVQDNLYNVLEGDDKHDDAPVVLNEKDRTAIQQRHDQLRDMVWIAEQLPGMMTKKDVTQGFLVPGNTSWLANGVPYFKNVLELSGVNYSEDQQLTVADEEELTSLASVDKYLRTHGFRGDLLGSQESIAYGNIDLKLFSYNARLGISDFHAFAGPVFLRFQHTQPRTLEDEGQDGGVPPAASMGDERLSVSIEDADSLAEMELITERRSVRNDMRAIAMRKIGSGPFKWSEMSPVEEGGGHEGHPDEWNFDKVSPKWAW-----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : **: . . *.: *** * : . * .* . *::*: .**. :*:.: .: .: : : ** *** ** :: ::::* .. . .: ::*:: .: ::: : : * :*:: .::*::*: * :: ** : : :.: :: ::*:..*: ** . *:. . * : : .: * *:: *. : *.**: :*::**** *::.*: : .: . . ::*:.***:* * **** :.. *: . . * * * * *:.::. * .** :::. : *:. :* : * :*::.:**:*:.:: .: :. :::.**:* : .: *: : : * : .:*:.:.: : ** .: :. : . . .. : * :* * . : : *.* . . :* .. *. : *.... * .:*:: * :: : . :: * *.*..:. *.* *: ::*: :: * ", "identical_positions": 102, "similar_positions": 206, "identity": "15.29%" }, { "cls_id": "homologset.agr.RGD:1308737", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JM05-1", "uniprot_id": "PIAS4_MOUSE", "id": "Q9JM05-1", "name": "E3 SUMO-protein ligase PIAS4", "aln": "-------------------------------------MAAELVEAKNMVMSFRVSDLQMLLGFVGRSKSGLKHELVTRALQLVQFDCSPELFKKIKELYETRYAKKSAEPG----------PQAPRPLDP--LALHS-------MPRTPLSGPTVDYPVLYGKYLNGLGRLPTKTLKPEVRLVKLPFFN--------MLDELLKPTELVPQSAEKLQESPCIFALTPRQVEMIRNSRELQPG---VKAVQVVLRICYSDTSCPQEDQYPPNIAVKVNHSYCSVPGYYPSNKPGVEPKRPCRPINLTHLMYLS-SATNRITVTWG-NYGKSYSVALYLVRQLTSSDLLQRLKTIGVKHPELCKALVKEKLRLDPDSEIATTGVRVSLICPLVKMRLSVPCRAETCAHLQCFDAVFYLQMNEKKPTWMCPVCDKPAAYDQLIIDGLLSKILSEC---EGADEIEFLAEGSWR---------------------------------------------------------------------------PIRAEKEP-------------SCSPQGPILVLGTSDANGLAPASSTPGIGSGLSGP---------------GSAGSGAGAAGSLENGKTGADVVDLTLDSSSS----------------------SEDEDEDEDDDEDEDE--GPRPKR-RCPFQKGLVPAC----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B5DFF9-1", "uniprot_id": "B5DFF9_RAT", "id": "B5DFF9-1", "name": "E3 SUMO-protein ligase PIAS4", "aln": "-------------------------------------MAAELVEAKNMVMSFRVSDLQMLLGFVGRSKSGLKHELVTRALQLVQFDCSPELFKKIKELYETRYAKKSAEPG----------PQAPRPLDP--LALHS-------MPRTPLSGPTVDYPVLYGKYLNGLGRLPTKALKPEVRLVKLPFFN--------MLDELLKPTELVPQSAEKLQESPCIFALTPRQVEMIRNSRELQPG---VKAVQVVLRICYSDTSCPQEDQYPPNIAVKVNHSYCSVPGYYPSNKPGVEPKRPCRPINLTHLMYLS-SATNRITVTWG-NYGKSYSVALYLVRQLTSSDLLQRLKTIGVKHPELCKALVKEKLRLDPDSEIATTGVRVSLICPLVKMRLSVPCRAETCAHLQCFDAVFYLQMNEKKPTWMCPVCDKPAAYDQLIIDGLLSKILSEC---EDADEIEFLAEGSWR---------------------------------------------------------------------------PIRAEKEP-------------SCSPQGPILVLGTSDANGLAPASSTPGMGSGLSGP---------------GGAGGGAGAAGGLENGKTGADVVDLTLDSSSS----------------------SEDEDEDEDDDEDDDE--GPRPKR-RCPFQKGLVPAC----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N2W9-1", "uniprot_id": "PIAS4_HUMAN", "id": "Q8N2W9-1", "name": "E3 SUMO-protein ligase PIAS4", "aln": "-------------------------------------MAAELVEAKNMVMSFRVSDLQMLLGFVGRSKSGLKHELVTRALQLVQFDCSPELFKKIKELYETRYAKKNSEPA----------PQPHRPLDP--LTMHSTYDRAGAVPRTPLAGPNIDYPVLYGKYLNGLGRLPAKTLKPEVRLVKLPFFN--------MLDELLKPTELVPQNNEKLQESPCIFALTPRQVELIRNSRELQPG---VKAVQVVLRICYSDTSCPQEDQYPPNIAVKVNHSYCSVPGYYPSNKPGVEPKRPCRPINLTHLMYLS-SATNRITVTWG-NYGKSYSVALYLVRQLTSSELLQRLKTIGVKHPELCKALVKEKLRLDPDSEIATTGVRVSLICPLVKMRLSVPCRAETCAHLQCFDAVFYLQMNEKKPTWMCPVCDKPAPYDQLIIDGLLSKILSEC---EDADEIEYLVDGSWC---------------------------------------------------------------------------PIRAEKER-------------SCSPQGAILVLGPSDANGLLPAPSVN--GSGALG------------------STGGGGPVGSMENGKPGADVVDLTLDSSSS----------------------SEDEEEEEEEEEDEDEE-GPRPKR-RCPFQKGLVPAC----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R4C4-1", "uniprot_id": "PIS4A_DANRE", "id": "F1R4C4-1", "name": "E3 SUMO-protein ligase PIAS4-A", "aln": "-------------------------------------MAAELVEAMNMVKSFRVSDLQTLLASMGRSKSGLKQDLVGRALRLVQTEYSPELLKNVRQLYETRFPKASAWLA----------ARRPETVAVNYPALNS-------SPRGTGQG---------TDYLNGIP-KPAPPPAAEVKLVPLPFYH--------NLETLLPPTELVAQNSEKLQESQCVFDLTPNQVDQIRNSSELRPG---MKSVQVVLRICYTDSIGVQEDQYPPNIAVKVNQSYCHVPGYYPSNKPGVEPRRPCRPVNITPWLHLS-TVTNRVTITWG-NFGKRYSVAVYLVRVFTSGELFNQLKHCSVENPDRCRERIQDKLRFDPESEIATTGLRVSLICPLVKMRLGVPCRVLTCAHLQCFDAVFFLQMNEKKPTWTCPVCDKPAPFELLTIDGLLSEILKETP--EDVEEIEYLTDGSWR---------------------------------------------------------------------------PIRDDKEKERE-------RENSRTPDYPVVDICVPEANGHSPAHSGTN-QTGKSG------------------SGGASAGTGSTSGGSGGGTVVDLTLDDSSE----------------------EEGGGGAEDSEETDDSQDSPAPKRGRYDYDKDLVTAY----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z7P5-1", "uniprot_id": "A1Z7P5_DROME", "id": "A1Z7P5-1", "name": "", "aln": "MRKTRSQTARTQAENAATSSSPGHQSTSSAPIAVNPFDSTKYKECEQMVQMLRVVELQKILSFLNISFAGRKTDLQSRILSFLRTN-LELLAPKVQEVYAQSVQEQNATLQYIDPTRMYSHIQLPPTVQPNPVGLVG-------SGQGVQVPGGQMNVVGGAPFLHTHSINSQLPIHPDVRLKKLAFYD--------VLGTLIKPSTLVPRNTQRVQEVPFYFTLTPQQATEIASNRDIRNSSKVEHAIQVQLRFCLVETSCDQEDCFPPNVNVKVNNKLCQLPNVIPTNRPNVEPKRPPRPVNVTSNVKLSPTVTNTITVQWCPDYTRSYCLAVYLVKKLTSTQLLQRMKTKGVKPADYTRGLIKEKLTEDADCEIATTMLKVSLNCPLGKMKMLLPCRASTCSHLQCFDASLYLQMNERKPTWNCPVCDKPAIYDNLVIDGYFQEVLGSSLLKSDDTEIQLHQDGSWSTPGLRSETQILDTP---------------------------------------SKPAQKVEVISDDIELISDDAKPVKRDLSPAQD-------EQPTSTSNSETVDLTLSDSDDDMPLAKRRPPAKQAVAS---------------STSNGSGGGQRAYTPAQQPQQSESPEQQASRQ----------------------SPEKQTVSEQQLQQQQHEQPATAAVHASLLESLAAAVADQKHFQLLDLAAVAAAAAATASSGQSQNAGP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12216-1", "uniprot_id": "SIZ2_YEAST", "id": "Q12216-1", "name": "E3 SUMO-protein ligase SIZ2", "aln": "------MASVMSNNNNNNNNNNASYMFTNPLSNTGGGLINEIKDAINEMEQLKVLELKQICKSLDLSITGKKAVLQDRIKQFLRKSCDIGHIDPWRPKAIKILIAKVRINS-----SLPKYSTLWETLKTG------------------------AFKHPVASGQLPVTALQSTALPPYSQQQALAYS---------FTSPFYKPIVQIPDANKKLKQSAGRGCTKMKFKVSKSNHDLLKS----NKSYKLYLFSGFSIPFIYETVGHEAIDFPYPCELVFNGTKLEDNVKGLKKQNGTGNPANLTPYLKVP-TEMNHLDLHYL-NIDKEYSISCFIVEVFSPEALLGKILKRPKIIKQATTAYIKRTLNEQDDDDIITTSTVLSLQCPISCTRMKYPAKTDQCKHIQCFDALWFLHSQSQVPTWQCPICQHPIKFDQLKISEFVDNIIQNCN--EDVEQVEISVDGSWKPIHN--------------------------------------------------SSAVITDTVNQNHSVKNENQGTVKQEQDYDSRNAFDTNLRNGSNHNEPEIISLDSSDDEAFIPASKS-FPTHVNPR----------NDQLRADIFPSESEGSSDYNPNHTSTPKGSPTMDQDNY----------------------QDAFQMRSFLNQGATTNINDTPTNNSS--INSFVTATNGDSRIFYNRGPSTPLLPAVLQNLTNQTEAQ--------RNPYGPNYNTTAQDRNLLG---------------------------------------------------IEGDLPPIPPVDPNSEAETELPTRTTSAAHLPPYIHVSTSG--------HGDDGKIRKRRHSNVSIYIPKNPYATLMKRRPQANHAIMNKTLAQTNDFN---TSAQDNSEVVDLTSD", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q04195-1", "uniprot_id": "SIZ1_YEAST", "id": "Q04195-1", "name": "E3 SUMO-protein ligase SIZ1", "aln": "----------MINLEDYWEDETP-----GPDREPTNELRNEVEETITLMELLKVSELKDICRSVSFPVSGRKAVLQDLIRNFLQNALVVGKSDPYRVQAVKFLIERIRKNE-----PLPVYKDLWNALRKGTPLSAITVRSMEGPPTVQQQSPSVIRQSPTQRRKTSTTSSTSRAPPPTNPDASSSSSSFAVPTIHFKESPFYKIQRLIPELVMNVEVTGGRGMCSAKFKLSKADYNLLSNP---NSKHRLYLFSGMINPLGSR--GNEPIQFPFPNELRCNNVQIKDNIRGFKSKPGTAKPADLTPHLKPY-TQQNNVELIYA-FTTKEYKLFGYIVEMITPEQLLEKVLQHPKIIKQATLLYLKKTLREDEEMGLTTTSTIMSLQCPISYTRMKYPSKSINCKHLQCFDALWFLHSQLQIPTWQCPVCQIDIALENLAISEFVDDILQNCQ--KNVEQVELTSDGKWTAILEDDDDSDSDSNDGSRSPEKGTSVSDHHCSSSHPSEPIIINLDSDDDEPNGNNPHVTNNHDDSNRHSNDNNNNSIKNNDSHNKNNNNNNNNNNNNNDNNNSIENNDSNSNNKHDHGSRSNTPSHNHTKNLMNDNDDDDDDRLMAEITSNHLKSTNTDILTEKGSSAPSRTLDPKSYNIVASETTTPVTNRVIPEYLGNSSSYIGKQLPNILGKTPLNVTAVDNSSHLISPDVSVSSPTPRNTASNASSSALSTPPLIRMSSLDPRGSTVPDKTIRPPINSNSYTASISDSFVQPQESSVFPPREQNMDMSFPSTVNSRFNDPRLNTTRFPDSTLRGATILSNNGLDQRNNSLPTTEAITRNDVGRQNSTPVLPTLPQNVPIRTNSNKSGLPLINNENSVPNPPNTATIPLQKSRLIVNPFIPRRPYSNVLPQKRQLSNTSSTSPIMGTWKTQDYGKKYNSG", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : ::* :*: : :. . :* * * ::: : .: . . . : :. .:: . . . : :: * . . . . . : . . .* ::* : : * : : : : * : ::*. ::. *: :: : :: .* : : : ** :** **: :: *.: * *:***** :*: : : *** **:*: : * *. ...:: . .. ::: :*.* .:: : . . : . : . . : . . . : . . ... ", "identical_positions": 38, "similar_positions": 116, "identity": "4.07%" }, { "cls_id": "homologset.agr.RGD:1308738", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P81128-1", "uniprot_id": "RHG35_RAT", "id": "P81128-1", "name": "Rho GTPase-activating protein 35", "aln": "MMMARKQDVRIPTYNISVVGLSGTEKEKGQCGIGKSCLCNRFVRPSADEFHLDHTSVLSTSDFGGRVVNNDHFLYWGEVSRSLEDCVECKMHIVEQTEFIDDQTFQPHRSTALQPYIKRAAATKLASAEKLMYFCTDQLGLEQDFEQKQMPDGKLLVDGFLLGIDVSRGMNRNFDDQLKFVSNLYNQLAKTKKPIVIVLTKCDEGVERYIRDAHTFALSK---KNLQVVETSARSNVNVDLAFSTLVQLIDKSRGKTKIIPYFEALKQQSQQIATAKDKYEWLVSRIVKSHNENWLSVSRKMQASPEYQDYVYLEGTQKAKKLFLQHIHRLKHEHIERRRKLYLAALPLAFEALIPNLDEVDHLS---CIKAKKLLETKPEFLKWFVVLEETPWDETSHIDNMENER-IPFDLMDTVPAEQLYETHLEKLRNERKRAEMRRAFKENLETSPFITPGKPWEEARSFIMNEDFYQWLEESVYMDIYGKHQKQIIDRAKEEFQELLLEYSELFYELELDAKPSKEKMGVIQDVLGEEQRFKALQKLQAERDALILKHIHFVYHPTKETCPSCPACVDAKIEHLISSRFIR--PSDRNQKNSLSDPNIDR-INLVILGKDGLARELANEIRALCTNDDKYVIDGKMYELSLRPIEGNVRLPVNSFQTPTFQPHGCLCLYNSKESLSYVVESIEKSRESTLGRRDNHLVHLPLTLILVNKRG-----DTSGETLHSLIQQGQQIASKLQCVFLDPASAGIGYGRNINEKQISQVLKGLLDSKRNLNLVSST-------ASIKDLAD------VDLRIVMCLMCGDPFSADDILSPVLQSQTCK-SSHCGSSNSVLLELPIGVHKKRIELSVLSYHSSFSIRKSRLVHGYIVFYSAKRKASLAMLRAFLCEVQDIIPIQLVALTDG--AIDVLDNDLSREQLTEGEEIAQEIDGRFTSIPCSQP-----QHKLELFHPFFKDVVEKKNIIEATHMYDNVAEAC-------STTEEVFNSPRAGSPLCNSNLQDS------------------EEDVEPPSYHLFREDATLPSLSKDHSKFSMELEGNDGLSFIMSNFESKLNNKVPPPVKPKPPVHFEITK-DLSYLDQGHREG--QRKSMSSSPWMPQDG---FDPSDYAEPMDAVVKPR-NEEEN----------------------------IYSVPHDSTQGKIITIRNINK--------AQSNGSGNGSDSEMDTSSLERGRK--------------VSAV-SKPVLYRTRCTRLGRFASYRTSFSVGSDDELGPIRKKEEDQASQGY-------------------------------KGDNAVIPYETDEDPRRRNILRSL-RRNTKKPKPKPRPSITKATWESNYFGVPLTTVVTP--------EKPIPIFIERCIEYIEATGLSTEGIYRVSGNKSEMESLQRQFDQDHNLDLAEKDFTVNTVAGAMKSFFSELPDPLVPYSMQIDLVEAHKIN-------------DREQKLHALKEVLKKFPKENHEVFKYVISHLNRVSHNNKVNLMTSENLSICFWPTLMRPDFSSMDALTATR-SYQTIIELFIQQCPFFFYNRPISEPPGAAPGSPSA-----------MAPTVPFLTSTPATS--QPSPPQSPPPTPQSPMQPLLS-----SQLQAEHTL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91YM2-1", "uniprot_id": "RHG35_MOUSE", "id": "Q91YM2-1", "name": "Rho GTPase-activating protein 35", "aln": "MMMARKQDVRIPTYNISVVGLSGTEKEKGQCGIGKSCLCNRFVRPSADEFHLDHTSVLSTSDFGGRVVNNDHFLYWGEVSRSLEDCVECKMHIVEQTEFIDDQTFQPHRSTALQPYIKRAAATKLASAEKLMYFCTDQLGLEQDFEQKQMPDGKLLVDGFLLGIDVSRGMNRNFDDQLKFVSNLYNQLAKTKKPIVVVLTKCDEGVERYIRDAHTFALSK---KNLQVVETSARSNVNVDLAFSTLVQLIDKSRGKTKIIPYFEALKQQSQQIATAKDKYEWLVSRIVKNHNENWPSVSRKMQASPEYQDYVYLEGTQKAKKLFLQHIHRLKHEHIERRRKLYLAALPLAFEALIPNLDEVDHLS---CIKAKKLLETKPEFLKWFVVLEETPWDATSHIDNMENER-IPFDLMDTVPAEQLYETHLEKLRNERKRAEMRRAFKENLETSPFITPGKPWEEARSFIMNEDFYQWLEESVYMDIYGKHQKQIIDRAKEEFQELLLEYSELFYELELDAKPSKEKMGVIQDVLGEEQRFKALQKLQAERDALILKHIHFVYHPTKETCPSCPACVDAKIEHLISSRFIR--PSDRNQKNSLSDLNIDR-INLVILGKDGLARELANEIRALCTNDDKYVIDGKMYELSLRPIEGNVRLPVNSFQTPTFQPHGCLCLYNSKESLSYVVESIEKSRESTLGRRDNHLVHLPLTLILVNKRG-----DTSGETLHSLIQQGQQIASKLQCVFLDPASAGIGYGRNINEKQISQVLKGLLDSKRNLNLVSST-------ASIKDLAD------VDLRIVMCLMCGDPFSADDVLSPVLQSQTCK-SSHCGSSNSVLLELPIGLHKKRIELSVLSYHSSFSIRKSRLVHGYIVFYSAKRKASLAMLRAFLCEVQDIIPIQLVALTDG--AIDVLDNDLSREQLTEGEEIAQEIDGRFTSIPCSQP-----QHKLELFHPFFKDVVEKKNIIEATHMYDNVAEAC-------STTEEVFNSPRAGSPLCNSNLQDS------------------EEDVEPPSYHLFREDATLPSLSKDHSKFSMELEGNDGLSFIMSNFESKLNNKVPPPVKPKPPVHFDITK-DLSYLDQGHREG--QRKSMSSSPWMPQDG---FDPSDYAEPMDAVVKPR-NEEEN----------------------------IYSVPHDSTQGKIITIRNINK--------AQSNGSGNGSDSEMDTSSLERGRK--------------VSAV-SKPVLYRTRCTRLGRFASYRTSFSVGSDDELGPIRKKEEDQASQGY-------------------------------KGDNAVIPYETDEDPRRRNILRSL-RRNTKKPKPKPRPSITKATWESNYFGVPLTTVVTP--------EKPIPIFIERCIEYIEATGLSTEGIYRVSGNKSEMESLQRQFDQDHNLDLAEKDFTVNTVAGAMKSFFSELPDPLVPYSMQIDLVEAHKIN-------------DREQKLHALKEVLKKFPKENHEVFKYVISHLNKVSHNNKVNLMTSENLSICFWPTLMRPDFSSMDALTATR-SYQTIIELFIQQCPFFFYNRPISEPPGAAPGSPSA-----------MAPTVPFLTSTPATS--QPSPPQSPPPTPQSPMQPLLS-----SQLQAEHTL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NRY4-1", "uniprot_id": "RHG35_HUMAN", "id": "Q9NRY4-1", "name": "Rho GTPase-activating protein 35", "aln": "MMMARKQDVRIPTYNISVVGLSGTEKEKGQCGIGKSCLCNRFVRPSADEFHLDHTSVLSTSDFGGRVVNNDHFLYWGEVSRSLEDCVECKMHIVEQTEFIDDQTFQPHRSTALQPYIKRAAATKLASAEKLMYFCTDQLGLEQDFEQKQMPDGKLLVDGFLLGIDVSRGMNRNFDDQLKFVSNLYNQLAKTKKPIVVVLTKCDEGVERYIRDAHTFALSK---KNLQVVETSARSNVNVDLAFSTLVQLIDKSRGKTKIIPYFEALKQQSQQIATAKDKYEWLVSRIVKNHNENWLSVSRKMQASPEYQDYVYLEGTQKAKKLFLQHIHRLKHEHIERRRKLYLAALPLAFEALIPNLDEIDHLS---CIKAKKLLETKPEFLKWFVVLEETPWDATSHIDNMENER-IPFDLMDTVPAEQLYEAHLEKLRNERKRVEMRRAFKENLETSPFITPGKPWEEARSFIMNEDFYQWLEESVYMDIYGKHQKQIIDKAKEEFQELLLEYSELFYELELDAKPSKEKMGVIQDVLGEEQRFKALQKLQAERDALILKHIHFVYHPTKETCPSCPACVDAKIEHLISSRFIR--PSDRNQKNSLSDPNIDR-INLVILGKDGLARELANEIRALCTNDDKYVIDGKMYELSLRPIEGNVRLPVNSFQTPTFQPHGCLCLYNSKESLSYVVESIEKSRESTLGRRDNHLVHLPLTLILVNKRG-----DTSGETLHSLIQQGQQIASKLQCVFLDPASAGIGYGRNINEKQISQVLKGLLDSKRNLNLVSST-------ASIKDLAD------VDLRIVMCLMCGDPFSADDILFPVLQSQTCK-SSHCGSNNSVLLELPIGLHKKRIELSVLSYHSSFSIRKSRLVHGYIVFYSAKRKASLAMLRAFLCEVQDIIPIQLVALTDG--AVDVLDNDLSREQLTEGEEIAQEIDGRFTSIPCSQP-----QHKLEIFHPFFKDVVEKKNIIEATHMYDNAAEAC-------STTEEVFNSPRAGSPLCNSNLQDS------------------EEDIEP-SYSLFREDTSLPSLSKDHSKLSMELEGNDGLSFIMSNFESKLNNKVPPPVKPKPPVHFEITKGDLSYLDQGHRDG--QRKSVSSSPWLPQDG---FDPSDYAEPMDAVVKPR-NEEEN----------------------------IYSVPHDSTQGKIITIRNINK--------AQSNGSGNGSDSEMDTSSLERGRK--------------VSIV-SKPVLYRTRCTRLGRFASYRTSFSVGSDDELGPIRKKEEDQASQGY-------------------------------KGDNAVIPYETDEDPRRRNILRSL-RRNTKKPKPKPRPSITKATWESNYFGVPLTTVVTP--------EKPIPIFIERCIEYIEATGLSTEGIYRVSGNKSEMESLQRQFDQDHNLDLAEKDFTVNTVAGAMKSFFSELPDPLVPYNMQIDLVEAHKIN-------------DREQKLHALKEVLKKFPKENHEVFKYVISHLNKVSHNNKVNLMTSENLSICFWPTLMRPDFSTMDALTATR-TYQTIIELFIQQCPFFFYNRPITEPPGARPSSPSA-----------VASTVPFLTSTPVTS--QPSPPQSPPPTPQSPMQPLLP-----SQLQAEHTL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A5PF53-1", "uniprot_id": "A5PF53_DANRE", "id": "A5PF53-1", "name": "Rho GTPase-activating protein 35", "aln": "MMMAKKQESRLPIYNLVVVGLSGTEKEKGQCGVGKSCLCNRFVRPSADDFHLDHTSVLSTSDFGGRVVNNDHFLFWGEVGRVLEDGADCRMHVVEQTEFIDDQTFQPHRSTALLPYIKRAASTKLASAEKLMYFCTDQLGLEQDFEQKQMPEGKLQVDGFLLCVDVSRGMNRNFDDQMKFVTNLYNHLSKTKKPIVLVLTKCDEGVERYIKDSHTFAITK---KNLQVVETSARSNINVDLAFLTLIQLIDKGKGKPKIIPYFEALKHQSQLIASAKDRYEWLVNHIVKNHNETWPNVSRRMQTSPEYKEYVFLEGTGKAKKLFQQHIHRLKQEHTERRRKAYLSALPLALSSLVSELDEIEHLS---WSGVQKVLESKKDFDHWFVVLDDAPWEDTPHLDNMEDDR-IPFDVLDTTAAEILFDAHLEHLRNECKRAQMRHEFKGKLASSPFVTPGKPWEEARSFIMNEDFYQWLEEPEYLDIYNRHQKAIIDRAKEDFQELLLEYSELFYELEVDAKPSKEKMGAIQEVLGEEQRFKALQKLQAERDALVLKHIHFVYHPTKETCPNCPHCVDSKIEQILASCFPAQYPSFG--KSHITDAKVDR-INLVILGKDGLARELANEIRALCTNDDHYVLEGRMYELVLRPIEGNVRLPVNSFHTSTFTPHGCLCLYNSKESLSYVVESIEKLRESTLGRRDNHMAQLPLSLLLVSKRGVGGLSDIGGETAQALISQGQQVAIKLQCNYLEPSSPGTGYGRNVNEKQINQVLKALLETRRTSTFRSCSPPAPPLPPCIRDFQQ-DQSPEADLRIVMCLMCGDSYDIDQLLAPFLLPQHCKPTSPQTSGTSVLLEQTIGGHKLTIELSLLSYHSSFATRKSRLVHGYIAVYSASRKASFETLCAFLCEVQDIIPVQMIAVGET--QIELQDSESARELLVQGEELAHELEGRFGSIVCGHGGVVGGLHKLDLLEQFFTEVLEKKTIVEASHMYESMAEAS-------STNENVY-SPHCGSPSPVTMLLDS------------------EEDMEASPPY----HDGTLTSHGGFKLPDLDSGDTFSVISDLSTFENKLNNKVPPQVRPKPSVTFDLRKPS----FNPYVDGVSHRRSLTSNVTWPLGGD--YDPSDYAEPMDAVSKPRPSYEDS----------------------------IYSVPHDSTQGKIITIRNSNR--------IHSNGGGNGSDSEGDGSSLERRRK--------------FSAARVKPRLYRDRSKRLGKFSSFRTSFSIGSDDEIGTLSRSKEDDVSP----------------------------------LKTDIT-NEEGEDPKKRNILKSL-RRPGKKARPKPRHS-ISKPLESNYFGVPLVNVVSF--------ERPIPVFIDKCIRYIEATGLTTEGIYRVSGNKAEIEGMQRQFEQDHNLDFVEKDFTVNTVAGAMKSFFSELPDPLVPYSSQEELVEAFKIN-------------DREQRLHTMKDVLRRFPRENFDVFKYVMSHLNKVGQWNRVNLMTSENLSICFWPTLMRPDFTSMDALTATR-TYQTIIETFIHQCAFFFYNQPPAESPTGLFGQPGP--MVPCGLPPSPTAAPSYCPSTPHFTPLLQSPPHSPPQSP-------------HSAPAEPQTL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E7F8G5-1", "uniprot_id": "E7F8G5_DANRE", "id": "E7F8G5-1", "name": "Rho GTPase-activating protein 35", "aln": "MMMAKKQDARAPTYNLVVVGLSGTEKEKGQCGVGKSCLCNRFVRPSADDFHLDHTSVLSTSDFGGRVVNNDHFLFWGEAVRMLEEGAECRMHVVEQTEFIDDQTFQPHRSTALQPYIKRAASTKLASAEKLMYFCTDQLGLEQDFEQKQMPEGKLLVDGFLLCVDVSRGMNRNFDDQMKFVTNLYNQLAKTKKPVVLVLTKCDEGVERYIKDSHTFALAK---KNLQVVESSARSNVNVDLAFITLVQLIDKSRGKPKIIPYFEALKQQSQQIATAKDRYEWLVSRIVKNHNETWPNTNRRMQTSPEYKDYVFLEGTSKAKKLFQQHVHRLKQEHIERRRKIYLSTLPQALNSLVPDLDEIDHLS---WSGVQKVLETKREFSHWFVVLDDTPWETTPHIDNMEDER-IPQDLLETPVAEGIYESHLEQLHNERKRAEMRWEFKEKLTCSPFVTPGKRWEEARSFIMNEEFYQWLEEQEYIDIYNKYQKIITDQAKEDFQELLLEYSELFYELEVDAKPSKEKMGAIQEVLGDEQRFKALQKLQAERDALVLKHIHFVYHPTKETCPSSPHCVDGKIEQHLALRYPTRYSFDGSSKSQFGEGKVDR-INLVILGKDGLARELANEIRALCTNDERYVLDGRTYELTLRPIEGNVRLPVNSFHTPTFAPHGCLCLYNSKESLSYVVDSIEKLRESTIGRRETNLVQLPLSLLLVTKRGVGSISDIGGETAQTLIQQGQQVAGRFQCSYLEPASPGVGYGRNINDKHLNQILRGLLEMRRPSVSLGSS--SPPLLPSLAGFRDSQQSTEGDLRIVMCLMCGDTYDVDQLLSPFLLPQHCRPLSNLSSGTSVLLDLSIGGQRLSIDLAILSYHSSFSLRKSRLVHGYIAVYSAKRKASMETLCAFLCEVQDIIPVQLLAVAET--QSELADSEAVRDQLAQGEELAHEIDARFSSVICGPGGVVGGLHRIDHFQPFFKEVVEKKTIVEATHMYDNVAEN--------VTNENVS-SPRCSSPS--ITLLDS------------------EDDIEPSPPYPTSRNDDTLT-RGGFKLPDLE-GDSYSLISEITNLENKINNKVPPQVRPKPNVTFDIPKTQNSSLYTDLALHGSNRRSLPS-VTWPEAG---YDPSDYAEPMDAVAKPRPTEEEN----------------------------IYSVPHDSTQGKIITIRNANK--------SHSNGAGNGSDSEADSSSLERRRK--------------LSALGVKPRLYRDRSKRLGKFSSFRTSF-IGSDDELGGTPKAKEDELGA----------------------------------QKGDTSLNEEGEDPKKRNILRSLGRRTTKKTRPKARQTSLSKPPESNYFGVPLANVVTP--------ERPIPLFIEKCIHYIETTGLSTEGIYRVSGNKAEMESMQRQFDQDPNIDLVEKDMSVNTVAGALKSFFSELPDPLVPYSMQVELVEAFKIN-------------DREHRLHTMKDVLRRFPRENYDVFKYVITHLNKVSLNSRLNLMTSENLSICFWPTLMRPDFTTMDALTATR-TYQTIIETFIHQCAFFFYNQPFADTPSGLPGQPASPTATLSSGSAYSTSYASIQPVAPPFSPAQQSPPHSPPPTPQSPIQSLLPPLHPHHTPTEQHML", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VX32-1", "uniprot_id": "RG190_DROME", "id": "Q9VX32-1", "name": "Rho GTPase-activating protein 190", "aln": "----------MRQFNISVIGLSGTEKDRGQVGVGKSCLCNRFMRPMADDYFIDHISVLSQSDFSGRIVNNDHFLYWGDVRKTTEEGVEYQFNIIEQTEFMDDSTFQAFKVGKMDPYSKRCTATKVFSAEKLMYICKNQLGIEKEYEQKVMPDGRLSIDGFVVVFDVSPVPNRSVEKQVEFVQNVIATILKNKKPLVLVTTKNDDAYELYVREAEKISQRKDYKSTVQLIETSAHESINIDLAFLLLAQMIDKVKNRVKIISYQESAKSRKELLDTRSEAVTRLIRNQITDYHVLWSQGSKMLSQYREWNEFLNIFGHEAGQKLFRRHMKKLRDDHLNKKLHQYLDKFALALEYLLPDIGALNISDDDAWECARNYLQNHIEFEQYFFECPQASWTELVDMDEAEDEARIPFDVLETSEAETVFRNYLNSVQQDKKKIGWKQQFKMLLEESGFVTPGKQLSEVRVLFMGRECFEALSEHDCQQIYDIHQDDIIEKSKQNFVELLLEHAQYFLQFKNVDNITQEDVRQITDVIQEDSRYKMLDRLDQERRLMLVQHLRFIHCPIRDHCPFFYNCVDSLIEEVLSDKSASNHKTPSGGGWKSSGSGSDRTLNLLIVGSEHLASDLLNDIRICTGSKGEYIYENQTYYLNYRIANG----DMEAFKAIDVYSSGLICVYSNQQSFETLKDNLERTLLCNLELEDKFEN---LPIVLVYQPQ-----DLKENEVEYLRNEGMRLSEMLHCDFIDHTQNHQKYVYDILN---IVILSLKLTEMKSYEPYPSN--------------------HTDLRILCCIFCGDQYDIENIVQPLVEESTLVKANEHS----IIVDVFIGDAKRRVEFILSSYHGTSQYR-DELIHGYIYFYSTKRRSSLANLS-ILAAQNANIPLQIIAVTESGGVNAFFNSDICQFLITEGNAVADRFKGSFMTFSADQY------VKFAFYNPFLKTAWDNKYEVENLHVEESITLDSGEGTLENSVNQMPRPPPRHESYMLSNTLGTDGSGSENYEMAPTRSLNSLNEERDISLDEIYDDNEKPKHLHQKWLEDKSDGRRNMNKNLIWNNFSGSTHAYTTGRRHIDSNLNKIRPKGPSQTLKVGEAPSRNCPAMSSSTFTLPTQQPGKLNMKNFQLVSDAVAKMNFTGSGSGSGSGSGSGSTGLGLGLGSGSGCMGDSFLEPVDKDGKRYDHAQLDGEDEDSEELAEYEQIYENEDCTESDSCASSTERRVRQQNAYYKASKKPVAAKKQKKKKVAIPVQTPRVPPFGSYVSPPEIPLHYQRMAVGGSGPEKPEPCVPEFMKSDKSPEYSMVPELAGAGIFGAENLPEYNMNQAKCLKDFEKLEKRRIKEETARQRKLQEKEKEQEKKLKRKLKQNAKGLVESAEAQFGKLMITSEQGEIPIFLNKCVEFIEKEGLDSEGIYRVPGSRAHVDMLFQRFEEDTNTEIDALDIPVNAVATALKDFFSKRLPPLFSKDIIKELEEIAGSRGVGNSKLNVEVKTDRSCRLIALKSLLQKLPPINFAILKYIFQHFVHVSDNSKLNSMDSKNLAICWWPTLIPIDFTDMGHFEQLRPYLEDIVQTMIDQFPYLFCGKDAFVMV------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*: *:*******::** *:*********:** **::.:** **** ***.**:*******:**:. : *: .: :::::*****:**.***..: : ** **.::**: *******:*.:***:*:::*** **:*:* :***:: .*** **..:.*::** *: : *.***:*:* ** *:. * *::::..:: * ..:*::*:**:..:*:**** * *:*** :.: ***.* *: * :.: : : .: *: . :..:: * . .: :. *::::: : * .:*** :*:::*:.:* ::: : ** :. *:. *:.::. :: . .:: *:.: :* ::*. ::.* .:*: *:: ** *:::* ** :: :*: :::: *: : ** * * *:**** .*.* ::*..: :: *.* :**. :*. * :::*::* *****::: * ::: : ::*.: * :*: ::.*:* *::*: ** ::::*::*:: * :: ** ***. **. :: ** :**:*:*.: ** :* *:** .. .*: :.: * * * :* :::*:: . . * :*:*..::*:. : :.:*: ..: .:. *.::** : * : . * .:* ::: ::* ::: :. * :: : :* * : .. ****: *::*** :. :::: *.: . . :::: ** : ::: : ***.: * ..*:**** .**:.*::*: * :*. : **:*::*: : . :.: : :.:*: :*..:.. * :. .. :: . *:. . ::* :* *: :. : ..: .*: * * . ::: : . . : . . ..:... : .. : .. : * .* * : .:: *** * . . . . : .* :*..: . : . :. : : ::*: ** ** : . * : *: *.*: :. : . : :. : *. .:*.* .. *: : : * : . . :.* *: . : **:*:::*:.:** ** :******.*.::.:: : ::*::* * :: *:.**:** *:*.***: **.. . :* * . **. :* ::*.:*:::* *. ::**:: *: :*. .::* * *:**:**:****: **: *. : * : *:: :*.* .::* .: ", "identical_positions": 358, "similar_positions": 514, "identity": "21.18%" }, { "cls_id": "homologset.agr.RGD:1308739", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4A9U0-1", "uniprot_id": "D4A9U0_RAT", "id": "D4A9U0-1", "name": "", "aln": "MELQSRSEALAVELARHQNGDLKKQLHERQPRIAALSDKQALGSSTAVPVTGPQVSSLQRLAGQGAAVLPQVRPKTLIPDSLPVTPGRDRPPKQPPTFQKATVVSIKNPSPALPTANNTVNHVPTPSSQTQALTEPTAITSPLSSAGVAYAIISTSPSNAATITPSTTVPVASDGIKVQPLLISADKK------------------------------------------VIIIQPQVKTQPESSAEPEPPTEEPSQGAQDTK---EDQPPSKENPEKIAFMVALGLVTTEHLEEIQSKRQERKRRSTANPAYSGFLETERKRLASSYLHNPLFLTARANEDPCWKGEITHDEFCAACKRGASLQPCGTCSGAYHLSCLDPPLKTAPKGVWVCPKCQRKALKKDEGVPWTGMLAIVHSYVTHKTVKEEEKQKLLQRGSELQSEHQQLEERDRQLASAVKKCLELKTSLLARQRGTQSSLDRIRALLRLIQGEQMLQVAVATTSPTPLLAGAWTKPSTTTTMRTSLQHPQNHN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C966-1", "uniprot_id": "PF21B_MOUSE", "id": "Q8C966-1", "name": "PHD finger protein 21B", "aln": "MELQSRSEALAVELARHQNGDLKKQLHERQPRIAALSDKQALGSTTAVPVTGPQVSSLQRLAGQGAAVLPQVRPKTLIPDSLPVTPGRDRPPKQPPTFQKATVVSIKNPSPALPTANNTVNHVPTPSSQTQALTEPTAITSPLSSAGVAYAIISTSPSNAATITPSTTVPVASDGIKVQPLLISADKK------------------------------------------VIIIQPQVKTQPESSAEPEPPTEEPSQGAQATK---EDQPPSKENPEKIAFMVALGLVTTEHLEEIQSKRQERKRRSTANPAYSGFLETERKRLASSYLHNPLFLTARANEDPCWKGEITHDEFCAACKRGASLQPCGTCSGAYHLSCLDPPLKTPPKGLWVCPKCQRKALKKDEGVPWTGMLAIVHSYVTHKTVKEEEKQKLLQRGSELQSEHQQLEERDRQLASAVKKCLELKTSLLARQRGTQSSLDRIRALLRLIQGEQMLQVAMATTSPTPLLAGPWTKPSTTTTMRTTLQHPQNHN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96EK2-1", "uniprot_id": "PF21B_HUMAN", "id": "Q96EK2-1", "name": "PHD finger protein 21B", "aln": "MELQSRPEALAVELARHQNGDLKKQLHERQPRIAALSDKQALGTITAVPVTGPQVSSLQRLAGQGAAVLPQVRPKTLIPDSLPVAPGRDRPPKQPPTFQKATVVSVKNPSPALPTANNTVSHVPAPGSQPQALAEPAALASPLSSAGVAYAIISTSPSNAAAMAPSTAVSVVSDSIKVQPLLISADNKPPPRLLSSPHPATHHCPLHPSSLPLTPPSPSLSPSPLHGIFQVIIIQPQVQTQPESTAESRPPTEEPSQGAQATKKKKEDRPPTQENPEKIAFMVALGLVTTEHLEEIQSKRQERKRRSTANPAYSGLLETERKRLASNYLNNPLFLTARANEDPCWKNEITHDEHCAACKRGANLQPCGTCPGAYHLSCLEPPLKTAPKGVWVCPRCQQKALKKDEGVPWTGMLAIVHSYVTHKTVKEEEKQKLLQRGSELQNEHQQLEERDRRLASAVQKCLELKTSLLARQRGTQSSLDRLRALLRLIQGEQLLQVTMTTTSPAPLLAGPWTKPSVAATHPT-VQHPQGHN", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******.************************************: ***************************************:********************:**************.***:*.**.***:**:*::*********************:::***:*.*.**.***********:* ********:*****:**..*********** ** **:**::******************************************:**********.**:****************.******.********.*******.********:*****.***:****:**:*******************************************.**********:*****:**********************:***********:***:::****:*****.*****.::* * :****.**", "identical_positions": 428, "similar_positions": 54, "identity": "80.45%" }, { "cls_id": "homologset.agr.RGD:1308740", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q7JWW5-1", "uniprot_id": "CTU1_DROME", "id": "Q7JWW5-1", "name": "Cytoplasmic tRNA 2-thiolation protein 1", "aln": "-----------------MHIICKSQCGNRAALKRPKTGDALCKECFFAAFEAEIHHTISSSNLFRRGEKVAVAASGGKDSTVLAHVLKLLNERHNYGLELVLLSIDEGITGYRDDSLETVKQNRDDYQMPLKILSYEELYG-WTMDRIVAQIG----RSNNCTFCGVFRRQALDRGAKLLGVDSIATGHNADDIAETVLMNVLRGDTARLRRCTSIRTGG-GEDTIPRVKPLKYSYEKEIVMYAHYKKLVYFSTECVFAPNAYRGHARAFLKDLEKVRPSVIMDIIYSGEQLRFKDT--------VKKPERGTCTRCGFVSSQQPCKACVLLEGLNRGLPKLGIGKKSKGERMIAKQNQELALRERANLVKNDF-------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q803X1-1", "uniprot_id": "CTU1_DANRE", "id": "Q803X1-1", "name": "Cytoplasmic tRNA 2-thiolation protein 1", "aln": "-----------------MPVQCSNCEQKRAVLKRPKTGHSLCKDCFFWAFEEEIHQTITSAGLFNRGETVAIGASGGKDSTVLAHVMKLLNERYDYGLKLLLLSVDEGITGYRDDSLETVKRNQQQYELPLKIVSYEELYG-WTMDAIVKQVG----LKNNCTFCGVFRRQALDRGAMMLNVDKICTGHNADDVAETVLMNVLRGDIARLRRCTAISTSSEGDGAIPRCKPLKYAYEKEIVLYAYFKKLDYFSTECIYSPNAYRGHARAFLKDLESVRPSAIIDVIHSGETLSVKEG--------VKMPVQGTCSRCGYISSQALCKSCVLLEGLNRGLPKLGIGKHHRLHGKILAQEP-LTEQEERKLKAVDF-------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P53088-1", "uniprot_id": "CTU1_YEAST", "id": "P53088-1", "name": "Cytoplasmic tRNA 2-thiolation protein 1", "aln": "MSFTAPSDPVNKPTKVKVSQLCELCHSRKALIRRPKNLSKLCKQCFCLVFETEIHNTIVANNLFQRGEKVAVGASGGKDSTVLAHMLKLLNDRYDYGIEIVLLSIDEGIIGYRDDSLATVKRNQQQYGLPLEIFSFKDLYD-WTMDEIVSVAG----IRNSCTYCGVFRRQSLDRGAAKLGISHVVTGHNADDMAETVLMNILRGDVARLEKSTAIITQS-SGSPIKRSKPFKYSYQKEIVLYAHYMKLDYFSTECTYAPEAFRGTAREYMKNLEAVRPSCIIDIIQSGENLALKAKKSNAGKRVVKFVDGNRCARCGYLSSNNICKACMLLEGLEKSRAQVAIENDTSADG---------AALKLRALEKLSF-------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "B1WBV0-1", "uniprot_id": "CTU1_RAT", "id": "B1WBV0-1", "name": "Cytoplasmic tRNA 2-thiolation protein 1", "aln": "----------------MPAPTCFSCHKARAALRRPRSGQALCGPCFCAAFEAEVLRTVLAGHLLPQGAVVAVGASGGKDSTVLAHVLRELAPR--LGITLHLVAVDEGIGGYRDAALEAVRSQAARWELPLTIVAYEDLFGGWTMDAVARSTAGSGRSRSCCTFCGVLRRRALEEGARLVGATHIVTGHNADDMAETVLMNFLRGDAGRLARGGVLGSTG-EGCALPRCRPLQFASQKEVVLYAHFRHLRYFSEECVYAPEAFRGHARDLLKLLEAARPSAVLDLVHSAERLALAPA--------AKPPPPGTCSRCGALASNKLCQACALLDGLNRGLPRLAIGKGRRVLQVEPPPLGNPSRVTSDPVALPEPCTCKQSKDESNPCGNGGD--------------------------------------RAGATCVSKSDLSPVAE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99J10-1", "uniprot_id": "CTU1_MOUSE", "id": "Q99J10-1", "name": "Cytoplasmic tRNA 2-thiolation protein 1", "aln": "----------------MPAPTCFSCHKTRAALRRPRSGQALCGSCFCAAFEAEVLHTVLAGHLLPPGAVVAVGASGGKDSTVLAHVLRELAPR--LGITLHLVAVDEGIGGYRDAALEAVRSQAARWELPLTIVAYEDLFGGWTMDAVARSTAGSGRSRSCCTFCGVLRRRALEEGARLVGATHIVTGHNADDMAETVLMNFLRGDAGRLARGGVLGSTG-EGCALPRCRPLQFASQKEVVLYAHFRHLRYFSEECVYAPEAFRGHARDLLKLLEAARPSAVLDLVHSAERLALAPA--------AKPPPPGTCSRCGALASHKLCQACALLDGLNRGLPRLAIGKGRRVLQVEPPQPGNPSLVTSDPVAPAGPCTCKQPKDKANPCGNGGDRAGATCVSQCDLSPGNGEDRAGATCVSQRDLSLGNGGDRAGATCVSQCDLSPVAE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z7A3-1", "uniprot_id": "CTU1_HUMAN", "id": "Q7Z7A3-1", "name": "Cytoplasmic tRNA 2-thiolation protein 1", "aln": "----------------MPAPPCASCHAARAALRRPLSGQALCGACFCAAFEAEVLHTVLAGRLLPPGAVVAVGASGGKDSTVLAHVLRALAPR--LGISLQLVAVDEGIGGYRDAALAAVRRQAARWELPLTVVAYEDLFGGWTMDAVARSTAGSGRSRSCCTFCGVLRRRALEEGARRVGATHIVTGHNADDMAETVLMNFLRGDAGRLARGGGLGSPG-EGGALPRCRPLQFASQKEVVLYAHFRRLDYFSEECVYAPEAFRGHARDLLKRLEAARPSAVLDLVHSAERLALAPA--------ARPPRPGACSRCGALASRALCQACALLDGLNRGRPRLAIGKGRRGLDEEATP-GTPGDPARPPASKAVPTF-----------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :* ::** . ** ** .** *: .*: : *: * **:.************::: * * *: : *:::**** **** :* :*: : : :** :.::::*:. **** :. . . **:***:**::*:.** :. : *******:*******.**** .** : : : . .: * :*:::: :**:*:**:: :* *** ** ::*:*:** ** :* ** .*** ::*:: *.* * . .: . *:*** ::*. *::* **:**::. .::.* : ", "identical_positions": 120, "similar_positions": 97, "identity": "26.85%" }, { "cls_id": "homologset.agr.RGD:1308742", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A2AS37-1", "uniprot_id": "A2AS37_MOUSE", "id": "A2AS37-1", "name": "", "aln": "MVLIPSQAMGFWGTLLFLIFLEQSWGQEQTYIISTPIVFRVGAPENVTVQAHGHTEAFDTTVSVKSYPDENVRYSFSTVNLSPENKFQNTAILTIQAKQLSEGQNSFSNSYLEVVSKHFAKLEIVPIIYDNDSLFVQTDKSVYTPQQPVKVRVYSVNDDLEPATRETVLTFIDPEGSQVDTIEGNNLTGIASFPDFEIPSNPKHGRWTVKAKYREDASKTGTTYFEVKEYDKTYRISIMPTIDLQPEVEKQEAHGMCLHQPTECLRQKINEQASTYKHPMIKKCCYDGARYNIHETCVQRAARVKIGPICVKAFTLCCNMAHQILENSTFKHIHLSSHSNHQAEHGDPQWRSQGKD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LN57-1", "uniprot_id": "A0ABK0LN57_RAT", "id": "A0ABK0LN57-1", "name": "", "aln": "MVLVPFQALGFWGTLLFLIFLEPSWEQEQTYIISTPIVFRVGAPENVTVQAYGYTEAFDTTISVKSYPNKNVNYSSGTVELSPENKFQNSAILTIQAQELSEEQNWFSNVYSEVVSKHFSKLEIMPIVYDNSSLFVHTDKPVYTPEQPVKVAVYSVDDDLEPVTRTTVLTF-DPEGSEVGIIGGRNGTGIASFPDFKIPSNPKLGRWTIKANYREDASTTGTTHFEVQGHEKAFKMAVMPTTDLQQKMEKQEAHVTC-HQTSDCLVQKINEQASKYKHPVIKKCCYDGARYNEHETCVQRAAHVTIGPNCVKAFSLCCEIAHQM----TFKHIHMSSLPNQWTERR-PQWRS-GRD", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:* **:************* ** *************************:*:*******:******::**.** .**:*********:*******::*** ** *** * *******:****:**:***.****:***.****:***** ****:*****.** ***** *****:*. * *.* *********:****** ****:**:******.****:***: ::*::::::*** *** ::****** * **.::** ********.****:************ *********:*.*** *****:***::***: ******:** .*: :*: ***** *:*", "identical_positions": 265, "similar_positions": 58, "identity": "74.44%" }, { "cls_id": "homologset.agr.RGD:1308743", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZTI7-1", "uniprot_id": "D3ZTI7_RAT", "id": "D3ZTI7-1", "name": "Serine/threonine-protein kinase/endoribonuclease IRE2", "aln": "---MARPVQSFQLWSALGFLLQLA-IFLGKLGPQVQSVRP-------------------------------------------------------------------------------ESLLFVSTLDGSLHALNKQTGDLKWTVKDDP------IIQGPMYVTEMAFLSDPA-DGSLYILGTQKQQGLMKLPFTIPELVHASPCRSS-------------DGVFYTGRKQDAWFVVDPESGETQMTL----------------TTEG-----FSTPQLYIGRTQYTVSMHDPRTP---TLRWNTTYRRYSAPPVD-GSPGKY-MSHLTSCGMGLLLTVDPGSGTVLWTQDLGVPVTGIYTWHQDGLRQLPHLTLAR--DTLHFLVLRWGHIRLPASSSQDTVTQFS-SLDTELLMTLYVGKEEAGFYVSKALVHAGVALVPRGLTLAPMDGPTTDEVTVQVSG-EREGSPSTAVRYPSGS-VALPSQWLLIGYHEPPPVLHTTMLRVQRTPGKGSAD---TRDSDDLHAPALSFEFLNLKREEPWDPELHPEEKA-DTYPGLGSQDLLAASFTAILLGAWVLYLMRQQQ--------QSPSAPAGPSDLP-QDTQVQLSRDTLQNQRRFQSPPEPVQPAHDP-------------EAEQPTVVGKIS---------FNPKDVLGRGAGGTFVFRGQFEGRAVAVKRLLRECFSLVQREVQLLQESDRHPNVLRYFCTEQGPQFHYIALELCQASLQEYVE-----SPDLDRW-GLGPTMVLQQMMSGLAHLHSLHIVHRDLKPGNILMAGPD--------SQGQGRVVISDFGLCKKLPAGRCSFSLHSGIP-GTEGWMAPELLQ-----------------------------LPPDSPTSAVDIFSAGCVFYYVLSGGSHPFGESLYRQANILSGDHCLAQLQEETHDK----VVALDLVKAMLSLLPQDRPSAGWVLAHPLFWSRAKELQFFQDVSDWLEKEPEQGP--LVTALEAGSYKVVR-ENWYKHISAPLQEDLKRFRSYKGTSVRDLLRAMRNKKHHYRELPTEVRQTLGQLPAGFAQYFTQRFPRLLLHTHRAMRTCASESLFLPYYPA-------------------------ALEARGSCQVPQRAETPRGPKGRPRS--------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z2E3-1", "uniprot_id": "ERN2_MOUSE", "id": "Q9Z2E3-1", "name": "Serine/threonine-protein kinase/endoribonuclease IRE2", "aln": "---MARPVQRFQLWSPLGFLLQLV-TLLGKLGPQVQSVRP-------------------------------------------------------------------------------ESLLFVSTLDGSLHALNKQTGDLKWTVKDDP------IIQGPMYVTEMAFLSDPA-DGSLYVLGTQKQQGLMKLPFTIPELVHASPCRSS-------------DGVFYTGRKQDAWFVVDPESGETQMTL----------------TTEG-----LSTPQLFIGRTQYTVSMHDLRTP---ALRWNTTYRRYSAPLLN-GSPGKY-MSHLTSCGMGLLLTVDPGSGIVLWTQDLGVPVTGIYTWHQDGLHQLPHLTLAR--DTLHFLVLRWGHIRLPASSYQDTATQFS-SLDTQLLMTLYVGKEEAGFYVSKALVHAGVALVPRGLTLAPMDGPTTDEVTLQVSG-EREGSPSTAVRYPSGS-VALPSQWLLIGYHEPPPVLHTTMLRVHPIPGKVSAE---TRASEDLHAPPVFFELLNLRRE---DPELHPEEKASDSYPGLGSQDLLAATFTAILLGAWVLYLMRQQQ--------QSPSAPAGPPDLS-QDAQGQLSRDILQDQRRFQSPSEPAQPPHDP-------------EAGQPTVVGKIS---------FNPKDVLGRGAGGTFVFRGQFEGRAVAVKRLLRECFGLVRREVQLLQESDRHPNVLRYFCTEHGPQFHYIALELCQASLQEYVE-----SPDLDRW-GLEPTTVLQQMMSGLAHLHSLHIVHRDLKPANILMAGPD--------SQGQGRVVISDFGLCKKLPVGRCSFSLHSGIP-GTEGWMAPELLQ-----------------------------LPPDSPTSAVDIFSAGCVFYYVLSGGSHPFGESLYRQANILSGDPCLAQLQEETHDK----VVALDLVRAMLSLLPQDRPSAGWVLAHPLFWSRAKELQFFQDVSDWLEKEPDQGP--LVSALEAGSYKVVR-EDWHKHISAPLQADLKRFRSYKGTSVRDLLRAMRNKKHHYRELPAEVRQTLGQLPAGFIQYFTQRFPRLLLHTHRAMRTCASESLFLPYYPP-------------------------ALEAR-------RPDATKS---------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q76MJ5-1", "uniprot_id": "ERN2_HUMAN", "id": "Q76MJ5-1", "name": "Serine/threonine-protein kinase/endoribonuclease IRE2", "aln": "---MASAVRGSRPWPRLGLQLQFAALLLGTLSPQVHTLRP-------------------------------------------------------------------------------ENLLLVSTLDGSLHALSKQTGDLKWTLRDDP------VIEGPMYVTEMAFLSDPA-DGSLYILGTQKQQGLMKLPFTIPELVHASPCRSS-------------DGVFYTGRKQDAWFVVDPESGETQMTL----------------TTEG-----PSTPRLYIGRTQYTVTMHDPRAP---ALRWNTTYRRYSAPPMD-GSPGKY-MSHLASCGMGLLLTVDPGSGTVLWTQDLGVPVMGVYTWHQDGLRQLPHLTLAR--DTLHFLALRWGHIRLPASGPRDTATLFS-TLDTQLLMTLYVGKDETGFYVSKALVHTGVALVPRGLTLAPADGPTTDEVTLQVSG-EREGSPSTAVRYPSGS-VALPSQWLLIGHHELPPVLHTTMLRVHPTLGSGTAE---TRPPENTQAPAFFLELLSLSREKLWDSELHPEEKTPDSYLGLGPQDLLAASLTAVLLGGWILFVMRQQQPQVVEKQQETPLAPADFAHIS-QDAQSLHSGASRRSQKRLQSPSKQAQPLDDP-------------EAEQLTVVGKIS---------FNPKDVLGRGAGGTFVFRGQFEGRAVAVKRLLRECFGLVRREVQLLQESDRHPNVLRYFCTERGPQFHYIALELCRASLQEYVE-----NPDLDRG-GLEPEVVLQQLMSGLAHLHSLHIVHRDLKPGNILITGPD--------SQGLGRVVLSDFGLCKKLPAGRCSFSLHSGIP-GTEGWMAPELLQL----------------------------LPPDSPTSAVDIFSAGCVFYYVLSGGSHPFGDSLYRQANILTGAPCLAHLEEEVHDK----VVARDLVGAMLSPLPQPRPSAPQVLAHPFFWSRAKQLQFFQDVSDWLEKESEQEP--LVRALEAGGCAVVR-DNWHEHISMPLQTDLRKFRSYKGTSVRDLLRAVRNKKHHYRELPVEVRQALGQVPDGFVQYFTNRFPRLLLHTHRAMRSCASESLFLPYYPP-------------------------DSEAR-------RPCPGATGR-------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1QQI8-1", "uniprot_id": "A0A8M1QQI8_DANRE", "id": "A0A8M1QQI8-1", "name": "Serine/threonine-protein kinase/endoribonuclease IRE1", "aln": "---MMRMMKN---WTQMLLLLVCFAGIVSQCEGGSSVSLP-------------------------------------------------------------------------------ESLLFVSTLDGSLHAVSKQTGDIKWTLKEDP------IIQVPEYFQEPGFLPDPN-DGSLYVLGGKRKEGLMKLPFTIQELVQSSPCRSS-------------DGVLYTGKKQDTWFVVDPQTGEKQTSL----------------STSSSDSICPSAPLLYIGRTEYMITMYDTKTQ---ELRWNATYNDYSAPLYD-DKKYEYKMSHFASSGDGLVVTVDRDSGEVLWMQKFDSPVAGFYLWSQDSLRRAPHLTVAT--ETLRYLTFTAENTQSHTMKWTYQFTKESHSTKTQLVPTLYVGKTESHLYASASLVHQGVAIVPKGLTLARIEGPMTAGVTMGNGRPECEITPSTDVKYPPGSSSSLQNQWLLIGHHEIPPLAHTTMLRDFPENLQRSGD---VIPPRGSGSSYRSPSHPLPPVRKQSSSPVLPDSLSSEPMTVLVVTLLLGAWITFLLTHKWPVKKSQRSEEPVDSTPLSGLTNYSASTELN-TPPSTSSYSNSSRSEKTSSVASNQTQPFSSKDSAPVTAASQSQNEQADVVEVGKIS---------FSPAEVLGHGTEGTFVFRGHFDGRRVAVKRILPECVEFAEREVQLLRESDEHPNVIRYFCTERDRQFTYIAIELCAATLQQYVE-----DPSCPHS-ELNPVSLLEQTMCGLSHLHSLNIVHRDLKPRNILLSLPG--------ALGRVRALISDFGLCKKLPDGRHSFSLRSGIP-GTEGWIAPELLIN----------------------------APKGNPTSAVDIFSAGCVFYYVTSKGQHPFGDTLRRQANILSGVYNLDHFMEDIHED----VIGRDLIERMISAEPESRPSAASILKHPFFWSPEKQLQFFQDVSDRIEKEPTESP--IVARLENSGRSVVR-TNWRMHISAPLQADLRKFRTYKGNSVRDLLRAMRNKKHHYHELPPEVQSALGEVPDGFVAYFTSRFPRLLLHTHTALSICAPERPFHPYYHH-----------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A8JR46-1", "uniprot_id": "A8JR46_DROME", "id": "A8JR46-1", "name": "non-specific serine/threonine protein kinase", "aln": "---MRFCVVVCCVLFLLASGLIASATAKSQQGDSAEVVSSGEDEKTDCTDLA----------------------------------------------------------------RDEEALMVFSTLGGGLTAIDPVTSEIRWTIADDPPI----VAEHQENVQVPHFLPDPR-DGSIYQLG--QMGSLKKLPYTIPQLVANAPCRSS-------------DGILYSGKKSDTWYMVDPKTGRREKVMGFG--------DATVDGKEGEQIGWATSRAIYLGRTQYTVMMYDSLAKNKDAKPWNITFYDYNAVSAPPELAKEYEYIHLTTTTNGQIVTLDRKHGKFLWQRDLSSPVVAAFLLGPDGLLSVPFTTVSD--EAYQAILEESKTGNVNT---------------VKLFQSLYVGEHQKGLYALPSLVDKNTPRISTAPPIKLLDGPTGDQNSNQETDPRTIYINDVLQEHAGIMLGHYNMPNEGNGNLQLSPTTASSKVVQSLATIHNYNDGYGLLANNEKNAADIGVQTDPELVEIGIDQRTNGNTINRTKTIILQNSNKVQAFINEWFMEHPSGKVHQILIVIVLGMIALFWYTCSTMRELQKQSENGSKTFAIAQNGSNGSTGSNGSNANAED----------LVDLGNGQVRVGKIS---------FSTNEVLGKGCEGTFVFKGTFEERFVAVKRLLPECFTFADREVALLRESDAHENVVRYFCTEQDRQFRYIAVELCAATLQDYTEG----DRSLELQNHIDVWQVLSQAASGLSHLHSLDIVHRDIKPQNVLISLPD--------AKGKVRVMISDFGLCKKLNFGKTSFSRRSGVT-GTDGWIAPEMMR-------------------------------SQRTTTAVDIFSLGCVYYYVLSGGHHAFGDNLKRQANILSHEYNLAKLRPEDDSEDSRIILAEQLISDMIHKDPQSRPPARCIGNHPLFWDEPKMLSFLQDVSDRVEKLQFHAE--PLKSLEKNGRIVVL-DDWNVHLDPMITDDLRKYRGYMGASVRDLLRALRNKKHHYHELTPAAQKMLGCIPHEFTNYWVDRFPQLISHAYHAFSICSNEPIFKPYYSAGYLFTRPWYFDADDALFPMLMLDPKPLPKIGSPKKTPSPASSQAQQLKQRKGLYNFRKPNDELPIPGVGLQRNLELDGQSLEPDGKRDVFANFKFRRYSKPGNNRNYNGGHKEAQDKEKYVIWTLPPSTQD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32361-1", "uniprot_id": "IRE1_YEAST", "id": "P32361-1", "name": "Serine/threonine-protein kinase/endoribonuclease IRE1", "aln": "MRLLRRNMLVLTLLVCVFSSIISCSIPLSSRTSRRQIVEDEVASTKKLNFNYGVDKNINSPIPAPRTTEGLPNMKLSSYPTPNLLNTADNRRANKKGRRAANSISVPYLENRSLNELSLSDILIAADVEGGLHAVDRRNGHIIWSIEPENFQPLIEIQEPSRLETYETLIIEPFGDGNIYYFN--AHQGLQKLPLSIRQLVSTSPLHLKTNIVVNDSGKIVEDEKVYTGSMRTIMYTINMLNGEIISAFGPGSKNGYFGSQSVDCSPEEKIKLQECENMIVIGKTIFELGIHSYDGAS-YNVTYSTWQQNVLDVPLALQNTFSKDGMCIAPFRDKSLLASDLDFRIARWVSPTFPGIIVGLFDVFNDLRTNENILVPHPFNPGDHESISSNKVYLDQTSNLSWFALSSQNFPSLVESAPISRYASSDRWRVSSIFEDETLFKNAIMGVHQIYNNEYDHLYENYEKTNSLDTTHKYPPLMIDSSVDTTDLHQNNEMNSLKEYMSPEDLEAYRKKIHEQISRELDEKNQNSLLLKFGSLVYRIIETGVFLLLFLIFCAILQRFKILPPLYVLLSKIGFMPEKEIPIVESKSLNCPSSSENVTKPFDMKSGKQVVFEGAVNDGSLKSEKDNDDADEDDEKSLDLTTEKKK--RKRGSRGGKKGRKSRIANIPNFEQSLKNLVVSEKILGYGSSGTVVFQGSFQGRPVAVKRMLIDFCDIALMEIKLLTESDDHPNVIRYYCSETTDRFLYIALELCNLNLQDLVESKNVSDENLKLQKEYNPISLLRQIASGVAHLHSLKIIHRDLKPQNILVSTSSRFTADQQTGAENLRILISDFGLCKKLDSGQSSFRTNLNNPSGTSGWRAPELLEESNNLQCQVETEHSSSRHTVVSSDSFYDPFTKRRLTRSIDIFSMGCVFYYILSKGKHPFGDKYSRESNIIRGIFSLDEMKCLHDRS--LIAEATDLISQMIDHDPLKRPTAMKVLRHPLFWPKSKKLEFLLKVSDRLEIENRDPPSALLMKFDAGSDFVIPSGDWTVKFDKTFMDNLERYRKYHSSKLMDLLRALRNKYHHFMDLPEDIAELMGPVPDGFYDYFTKRFPNLLIGVYMIVKENLSDDQILREFLYS----------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : : . . ::. : : *.* *:. ...: *:: : : : :: :* **.:* :. .* *** :* :** :* : . * .*:* : :: .*. : . : :*:* : : ::. :. . ::. ::: * * : :.* :. :. : : . : ::.. . : . . . . : . * : : : : .: :. . : :.:*. . . .:** * **.**:* *: * *****:* : :. *: ** *** * **:**:*:* :* ***:*** .**: .* . . :* * .*::*****.*:***:** *:*:: .. . * ::********* *: ** . . . **.** ***:: * ::**** ***:**: * * *.**:. *::**: * .: . . . :*: *: * **.* : **:** * *.*: .*** :* . : :: .. *: :* ::. : :*.::* * . .: *****:*** **: :*. . :* :* * *:..***.*: .: . : : : ", "identical_positions": 162, "similar_positions": 205, "identity": "12.94%" }, { "cls_id": "homologset.agr.RGD:1308744", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4AC19-1", "uniprot_id": "D4AC19_RAT", "id": "D4AC19-1", "name": "", "aln": "-----MTSLPCPLPGLGPSNVVFPDLAPASS---------VVAAYQLG-LSPGTAASPDLSFS---QTYGHLLSYSYP-----GPATPGDSYLSSQQQSAAPSRPFHQPTEHPQELEAESEKLALSLEPSQP---SLTRKLRKPRTIYSSLQLQHLNQRFQHTQYLALPERAQLAAQLGLTQTQVKIWFQNKRSKYKKLLKQS---------------------------SGELEED-FSGRPPSLSPHSLTLPSIWDLPKAGTLP---TSGYDNS-FGTWYQH-HSPDVLALPQRM-----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70436-1", "uniprot_id": "DLX4_MOUSE", "id": "P70436-1", "name": "Homeobox protein DLX-4", "aln": "-----MTSLPCPLPDRGASNVVFPDLAPALS---------VVAAYPLG-LSPGTAASPDLSYS---QSYGHPRSYSHP-----GPATPGDSYLPRQQQLVAPSQPFHRPAEHPQELEAESEKLALSLVPSQQQ--SLTRKLRKPRTIYSSLQLQHLNQRFQHTQYLALPERAQLAAQLGLTQTQVKIWFQNKRSKYKKLLKQS---------------------------SGEPEED-FSGRPPSLSPHSPALPFIWGLPKADTLP---SSGYDNSHFGAWYQH-RSPDVLALPQMM-----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92988-1", "uniprot_id": "DLX4_HUMAN", "id": "Q92988-1", "name": "Homeobox protein DLX-4", "aln": "-----MTSLPCPLPGRDASKAVFPDLAPVPS---------VAAAYPLG-LSPTTAASPNLSYS---RPYGHLLSYPYT-----EPANPGDSYLSCQQP-AALSQPLCGPAEHPQELEADSEKPRLSPEPSERRPQAPAKKLRKPRTIYSSLQLQHLNQRFQHTQYLALPERAQLAAQLGLTQTQVKIWFQNKRSKYKKLLKQN---------------------------SGGQEGD-FPGRTFSVSPCSPPLPSLWDLPKAGTLP---TSGYGNS-FGAWYQH-HSSDVLASPQMM-----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q98878-1", "uniprot_id": "DLX4B_DANRE", "id": "Q98878-1", "name": "Homeobox protein Dlx4b", "aln": "--MMSMSFMSDTLNSSDPSKSAFLEFGHGLASNQQHLSGFAHNIYPVHGLHSGGHLQHDAPYPSSAPHYSRPLGYAYPG--PVSAAAPG-AYMPYQPNNHSGALAHTRAENTNHEKPAVIENGEIRLN-------GKGKKIRKPRTIYSSVQLQALHQRFQQTQYLALPERADLAAKLGLTQTQVKIWFQNKRSKYKKIMKHG---------------------------SSGPEGELLHTSSSS--PCSPGLSQLWEVSMANKVPPMHPSSYMNN-YGHWYPP-HHQDPVPRPQMM-----------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q98879-1", "uniprot_id": "DLX4A_DANRE", "id": "Q98879-1", "name": "Homeobox protein Dlx4a", "aln": "---MTMTSLSESLEASDPSKSAFLEFSHGYQSHQQHSPGVSHAHYPVHGLHQGAHSQYDAAFSPGAASYSRPLAYHYS----TAHHHPG-AYLPYQ---HNSAVGYSRVEDADSEKQSSIESGEIRLN-------GKGKKIRKPRTIYSSLQLQALNQRFQQTQYLALPERADLAAKLGLTQTQVKIWFQNKRSKYKKIMKHG---------------------------SSGPEGEHLQAASASGAPCSPGMPPLWDVSMPSKGAPIHSGGYMNS-FGHWYSG-HHQDPMARTQMM-----------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P20009-1", "uniprot_id": "DLL_DROME", "id": "P20009-1", "name": "Homeotic protein distal-less", "aln": "MDAPDAPHTPKYMDGGNTAASVTPGINIPGK----------SAFVELQQHAAAGYGGIRSTYQHFGPQGGQDSGFPSPRSALGYPFPPMHQNSYSGYHLGSYAPPCASPPKDDFSISDKCEDSGLRVN-------GKGKKMRKPRTIYSSLQLQQLNRRFQRTQYLALPERAELAASLGLTQTQVKIWFQNRRSKYKKMMKAAQGPGTNSGMPLGGGGPNPGQHSPNQMHSGGNNGGGSNSGSPSHYLPPGHSPTPSSTPVSELSPEFPPTGLSPPTQAPWDQKPHWIDHKPPPQMTPQPPHPAATLHPQTHHHNPPPQMGGYVPQYWYQPETNPSLVTVWPAV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : ..: . : : .: .: .: . * : . . *. : . :*:*********:*** *::***:**********:***.**************:******::* *. : . * . . . . . . . . * : * . .* ", "identical_positions": 58, "similar_positions": 47, "identity": "16.86%" }, { "cls_id": "homologset.agr.RGD:1308745", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BU25-1", "uniprot_id": "PAMR1_MOUSE", "id": "Q8BU25-1", "name": "Inactive serine protease PAMR1", "aln": "----------------------------------------------------------------------------------------------MELDRWAQLGLVFLQLLLISSLPREYTVINEACPGAEWNIMCRECCEYDQIECLCPGKKEVVGYTIPCCRNEDNECDSCLIHPGCTIFENCKSCRNGSWGGTLDDFYVKGFYCAECRAGWYGGDCMRCGQVLRASKGQILLESYPLNAHCEWTIHARPGFIIQLRFGMLSLEFDYMCQYDYVEVRDGDNSDSPIIKRFCGNERPAPIRSTGSSLHVLFHSDGSKNFDGFHAVFEEITACSSSPCFHDGTCLLDTTGSFKCACLAGYTGQRCENLLEERNCSDLGGPVNGYKKITEGPGLLNERHVKIGTVVSFFCNGSYVLSGNEKRTCQQNGEWSGKQPVCMKACREPKISDLVRRRVLSMQVQSRETPLHQLYSTAFSKQKLQDASTKKPALPFGDLPPGYQHLHTQVQYECISPFYRRLGSSRRTCLRTGKWSGRAPSCIPICGKIESTPSPKTQGTRWPWQAAIYRRTSGVHDGGLHKGAWFLVCSGALVNERTVVVAAHCVTELGKATIIKTADLKVVLGKFYRDDDRDEKSIQNLRVSAIILHPNYDPILLDTDIAVLKLLDKARISTRVQPICLATTRDLSTSFQESHITVAGWNILADVRSPGFKNDTLHYGMVRVVDPMLCEEQHEDHGIPVSVTDNMFCASKDPSTPSDICTAETGGIAALSFPGRASPEPRWHLVGLVSWSYDKTCSNGLSTAFTKVLPFKDWIERNMK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0L414-1", "uniprot_id": "A0ABK0L414_RAT", "id": "A0ABK0L414-1", "name": "Inactive serine protease PAMR1", "aln": "MNIVPSLILAVPEPFLLPFPARYCPPHISTFTITKGWSRKSSEREQALVFRCFPVSRGASARASQGLRGELWADVVALAEGATPVTPGSAAVGTMELDRWAQLGLAFLQLLLISSLPREYTVINEACPGAEWNIMCRECCEYDQIECICPGKKEVVGYTIPCCRNEDNECDSCLIHPGCTIFENCKSCRNGSWGGTLDDFYVKGFYCAECRAGWYGGDCMRCGQVLRASKGQILLESYPLNAHCEWTIHARPGFIIQLRFSMLSLEFDYMCQYDYVEVRDGDNSDSPLIKRLCGNERPAPIRSTGSSLHVLFHSDGSKNFDGFHAAFEEITACSSSPCFHDGTCILDTTGSFKCACLAGYTGPRCENLLEERNCSDLGGPVNGYKKITGGPGLLNERHVKIGTVVSFFCNGSYVLSGNEKRTCQQNGEWSGKQPVCMKACREPKISDLVRRRVLSMQVQSRETPLHQLYSTAFSKQKLQDASTKKPALPFGDLPPGYQHLHTQVQYECISPFYHRLGSSRRTCLRTGKWSGRAPSCIPICGKIESVASPKTQGTRWPWQAAIYRRTSGVHDGGLHKGAWFLVCSGALVNERTVVVAAHCVTELGKVTIIKTADLKVVLGKFYRDDDRDEKTIQNLRISAIILHPNYDPILLDTDIAVLKLLDKARISTRVQPICLATTRDLSASFEESHITVAGWNILADVRSPGFKNDTLHYGMVKVVDSMLCEEQHEDHGIPVSVTDNMFCANKDPSTPSNICTAETGGIAALSFPGRASSEPRWHLVGLVSWSYDKTCSNSLSTAFTKVLPFKDWIERNMK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6UXH9-1", "uniprot_id": "PAMR1_HUMAN", "id": "Q6UXH9-1", "name": "Inactive serine protease PAMR1", "aln": "----------------------------------------------------------------------------------------------MELGCWTQLGLTFLQLLLISSLPREYTVINEACPGAEWNIMCRECCEYDQIECVCPGKREVVGYTIPCCRNEENECDSCLIHPGCTIFENCKSCRNGSWGGTLDDFYVKGFYCAECRAGWYGGDCMRCGQVLRAPKGQILLESYPLNAHCEWTIHAKPGFVIQLRFVMLSLEFDYMCQYDYVEVRDGDNRDGQIIKRVCGNERPAPIQSIGSSLHVLFHSDGSKNFDGFHAIYEEITACSSSPCFHDGTCVLDKAGSYKCACLAGYTGQRCENLLEERNCSDPGGPVNGYQKITGGPGLINGRHAKIGTVVSFFCNNSYVLSGNEKRTCQQNGEWSGKQPICIKACREPKISDLVRRRVLPMQVQSRETPLHQLYSAAFSKQKLQSAPTKKPALPFGDLPMGYQHLHTQLQYECISPFYRRLGSSRRTCLRTGKWSGRAPSCIPICGKIENITAPKTQGLRWPWQAAIYRRTSGVHDGSLHKGAWFLVCSGALVNERTVVVAAHCVTDLGKVTMIKTADLKVVLGKFYRDDDRDEKTIQSLQISAIILHPNYDPILLDADIAILKLLDKARISTRVQPICLAASRDLSTSFQESHITVAGWNVLADVRSPGFKNDTLRSGVVSVVDSLLCEEQHEDHGIPVSVTDNMFCASWEPTAPSDICTAETGGIAAVSFPGRASPEPRWHLMGLVSWSYDKTCSHRLSTAFTKVLPFKDWIERNMK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***. *:****.*****************************************:****:*************:*************************************************************.*********************:***:***** ********************** *. :***.*********:* ********************* :*****************:**.:**:********** ************* *******:*** ****:* **.***********.***********************:*:*****************.***************:********.*.************ ********:*********:******************************. .:***** ******************.****************************:***.*:**********************:**.*::***************:***:*******************::****:**:**********:**************: *:* ***.:**********************. :*::**:***********:*******.******:************: ********************", "identical_positions": 642, "similar_positions": 61, "identity": "78.87%" }, { "cls_id": "homologset.agr.RGD:1308746", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LF64-1", "uniprot_id": "A0ABK0LF64_RAT", "id": "A0ABK0LF64-1", "name": "", "aln": "MDTTESAESAHSPARSPSRSRCPPP---AQPGYLSAWIHPRAFSTLALCLPTTEPEDRLAPAQPRAPSTSALAPYPSPLPLPVPSALAKFELSRVARLTFFVRGLRLLSCRSEGFWRPWVRTPGEKE---ELAEPRAAEVLPSGPGMIEASRKLLQYQHPVRLFWPKSKCYDYLYQEAETLLKNFPIQATISFYEDSDSEDDVEGLACENQSN---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q2WG76-1", "uniprot_id": "RIPP2_MOUSE", "id": "Q2WG76-1", "name": "Protein ripply2", "aln": "MDTTESAESAHNPARPPSRSRCPPS---AQPG-------------------------------------------------------------------------------SEGFWRPWVRTPGEKE---KRTGPRAAEALPSGPGMAEASGKLLQYQHPVRLFWPKSKCYDYLYQEAETLLKNFPIQATISFYEDSDSEDEIEGLACENQSN---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5TAB7-1", "uniprot_id": "RIPP2_HUMAN", "id": "Q5TAB7-1", "name": "Protein ripply2", "aln": "MENAGGAEGTESGAAACAATDGPTRRAGADSG-------------------------------------------------------------------------------YAGFWRPWVDAGGKKE---EETPNHAAEAMPDGPGMTAASGKLYQFRHPVRLFWPKSKCYDYLYQEAEALLKNFPIQATISFYEDSDSEDEIEDLTCEN------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q2WG80-1", "uniprot_id": "RIPP1_DANRE", "id": "Q2WG80-1", "name": "Protein ripply1", "aln": "MNSVCFATPHTKHMDSKMQLTSSPA----------------------------------------------------------------------------------------SLWRPWLVTRKDAQTECRRTKLACPYSRPEVPGNTTTDGKMQSFQHPVRLYWPRSKSFDYLFSDGEALLRNFPVQATINFYDESDSEDEEESCDEDDESDVEDCLKHNSHFTAFN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:.. * . . .. .:****: : . : . : .. *. ** :. *: .::*****:**:**.:***:.:.*:**:***:****.**::*****: *. :: ", "identical_positions": 40, "similar_positions": 42, "identity": "17.54%" }, { "cls_id": "homologset.agr.RGD:1308747", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BFY7-1", "uniprot_id": "PIMRE_MOUSE", "id": "Q8BFY7-1", "name": "Protein PIMREG", "aln": "--------------MASQWQGMRTSVRRRSLLKEEQLEKKEVTRSAGGHPET--GPLGSLCRQFQRRLPLRAVSLNLGNGPSWKRLESPEPEQQGLQAAARSAKSALGAMSQRIQESCQSGTKWLMETQVKVRR-KRGAQKDRGSPPPSLSQKNTRLCRAN-----RDARVGGHLRLSGQMGPHAHRRQRLRRESALRSPCSSTEPLCSPSESDSDLEPVGAGIQHLQKLSQRLDRAIKAEES----GDMTVSLIRE-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7EXP2-1", "uniprot_id": "F7EXP2_RAT", "id": "F7EXP2-1", "name": "", "aln": "MEEDLSGRGNWTKHMASQWQGMRTSVRRRSLLKEEQLEK-EVTRSAGGHLET--GPLGSLCRQFQRRLPLRAVSLNLGNGPSWKRLETPEPEQQGLQAAARSAKSALGAMSQRIQESCQSGTKWLMETQVRVRR-KRGAQKDRGSPPPSLSPKNTRLCRAN-----RDARGGGLPRLSGQMGPHAHRRQRLRREAALRSPCSSTDPLCSPRQSDSDLEPVGAGIQHLQKLSQKLDKAIKAEES----GDMTVSLISE-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BSJ6-1", "uniprot_id": "PIMRE_HUMAN", "id": "Q9BSJ6-1", "name": "Protein PIMREG", "aln": "--------------MASRWQNMGTSVRRRSLQHQEQLEDSKELQPVVSHQETSVGALGSLCRQFQRRLPLRAVNLNLRAGPSWKRLETPEPGQQGLQAAARSAKSALGAVSQRIQESCQSGTKWLVETQVKARRRKRGAQKGSGSPTHSLSQKSTRLSGAAPAHSAADPWEKEHHRLSVRMGSHAHPLRRSRREAAFRSPYSSTEPLCSPSESDSDLEPVGAGIQHLQKLSQELDEAIMAEERKQALSDRQGFILKDVYASP", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***:**.* ******** ::****. : :.. .* ** *.*****************.*** ********:*** *****************:***************:****:.** ******. ***. *** *.***. * *. *** :**.*** :* ***:*:*** ***:***** :********************.**.** *** .* :: : ", "identical_positions": 161, "similar_positions": 35, "identity": "61.45%" }, { "cls_id": "homologset.agr.RGD:1308748", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AD71-1", "uniprot_id": "A0A8I6AD71_RAT", "id": "A0A8I6AD71-1", "name": "", "aln": "----------------------------------------------------MAEPPNP-----ARGPVAVLSEKEAFGKLQPSSRESPGSMS-AKKVRTEEKKGPRRVNGEGDSGGNGGQLQPPAAPSPQSYGSPAAWSFAARPAASSQATPRGCYAFSASPSV-SSASASSSQPVPRKLLVASSLLHAQPHRVLLPPVTPPAAA--------------------------KPRRPKEKREKEKRR-HGLG------GADRDENGEAKPLPRDKIKDKIKEKDKEKERERKKHKVMSEIK-------------------------KENGDVKIFLKKDPGSILSTPYGGSQPSVTPSSALQGGKEKPKTNIEDLQIKKVKKKKKKKHKENEKRKRPKMYSKSIQTICSGLLS-AEDQEAKGILNDNVKDCIGKHLDTKNCDSKVPDNSDFPFVSLKEPRVQNDLKR--------------------------------------------------------------LDTLEFKQLIHVEHQPNGGASVIHAYCSELSCLSPVEMRRFAEEFVGLAFSENESSAAFYVMGVVHGAATYLPDFLDYFSYNFPNSPVKMEILGKK-DIETTTMSNFHAQVKRTYSHGTYRAGPMRQISLVGAVDEEVGDYFPEFLDMLEESPFLKCTLPWGTLSSLKLESRKDSDDGPIMWVRPGEQMIPVADMP-KSPFKRKRT-TNEIKNLQYLPRTSEPREMLFEDRTRAHADHIGQGFERQTTAAVGVLKAVHCGQRPDQPRVTKDVICFHAEDFLEVVQRMQLDLHEPPLSQCVQWVDDAKLNQLRREGIRYARIQLYDNDIYFIPRNVVHQFKTVSAVCSLAWHVRLKLYHAED-TCHST--VTHEQGIPSGPTSSVLGTHTE------NQSSSDPVLSDRLHSKYESPQVKQEPVVSLNIKEEPVTVTVSAKTRTPNNTEGKSS-----------KAKSDHVQFSDFHIDMDSKFENTNKDLKEDLCPGSVQ-EVDTRQHSCIPSNQDRSDENNVC-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3Z0K6-1", "uniprot_id": "D3Z0K6_MOUSE", "id": "D3Z0K6-1", "name": "", "aln": "----------------------------------------------------MAEPPNP-----ARGAVALLSEKEASGKVQPSSREPPGSMS-AKKVRTEEKKAPRRVNGEGGSGGNGGQLQP------QSFGSPAAWSFAARPAASSSSTSRSCYSFSASPSV-SSASASSSQPLPRKLLVTPSLLHAQPHRVLLPPVAPPAAA--------------------------KPRRPKEKREKEKRRQHGLG------AAARDENGEAKPLPRDKIKDKIKEKDKE--REKKKHKVMSEIK-------------------------KENGDVKILLK-------------------------SGKEKPKTNIEDLQIKKVKKKKKKKHKENEKRKRPKMYSKSIQTICSGLLS-AEDQEAKSILSDNVKDCIGKNLDTKNCDSKIPDNSDFPFVSLKEPRDKNNLRR--------------------------------------------------------------LDTLAFRQLIHIEHQPNGGAAVIHAYSNELSCLSPMEMQRFAEEFVGLVFSENESSAAFYVMGIVHGAATYLPDFLDYFSYNFPNSPVKMEILGKK-DIETTTMSNFHAQVKRTYSHGTYRAGPMRQISLVGAVDEEVGDYFPEFLDMLEASPFLKCTLPWGTLSSLKLESRKDSDDGPIMWVRPGEQMIPVADMP-KSPFKRKRT-TNEIKNLQYLPRTSEPREMLFEDRTRAHADHIGQGFERQTTAAVGVLKAVHCGQRPDQPRVTKDVICFHAEDFLEVVQRMQLDLHEPPLSQCVQWVDDAKLNQLRREGIRYARIQLYDNDIYFIPRNVVHQFKTVSAVCSLAWHVRLKFYHAEEDTCHSTSESTHEKGIASGPTSSVLGAHTE------NQASSDSVLSDKLPSKYESQQIKHEPGAALRIKEEPGMAPIPEKIRTPNNTEGKNS-----------KARLDRAQFSDFHIDMDSAFENTNKDLKEDSCPGSVSNTVDTQQHSSVRSSQDRSEDDSLC-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6PCB5-1", "uniprot_id": "RSBNL_HUMAN", "id": "Q6PCB5-1", "name": "Lysine-specific demethylase RSBN1L", "aln": "----------------------------------------------------MAEPPSPVHCVAAAAPTATVSEKEPFGKLQLSSRDPPGSLS-AKKVRTEEKKAPRRVNGEGGSGGNSRQLQPPAAPSPQSYGSPASWSFAPLSAAPSPSSSRSSFSFSAGTAVPSSASASLSQPVPRKLLVPPTLLHAQPHHLLLPAAAAAASAN------------------------AKSRRPKEKREKERRR-HGLGGAREAGGASREENGEVKPLPRDKIKDKIKERDKEKEREKKKHKVMNEIK-------------------------KENGEVKILLK-------------------------SGKEKPKTNIEDLQIKKVKKKKKKKHKENEKRKRPKMYSKSIQTICSGLLTDVEDQAAKGILNDNIKDYVGKNLDTKNYDSKIPENSEFPFVSLKEPRVQNNLKR--------------------------------------------------------------LDTLEFKQLIHIEHQPNGGASVIHAYSNELSHLSPMEMERFAEEFVGLVFSENENSAAFYVMGIVHGAATYLPDFLDYFSFNFPNSPVKMEILGKK-DIETTTMSNFHAQVKRTYSHGTYRAGPMRQISLVGAVDEEVGDYFPEFLDMLEESPFLKCTLPWGTLSSLKLQSRKDSDDGPIMWVRPGEQMIPVADMP-KSPFKRKRT-TNEIKNLQYLPRTSEPREMLFEDRTRAHADHIGQGFERQTTAAVGVLKAVHCGEWPDQPRITKDVICFHAEDFLEVVQRMQLDLHEPPLSQCVQWVDDAKLNQLRREGIRYARIQLYDNDIYFIPRNVVHQFKTVSAVCSLAWHIRLKLYHSEEDTSQNT--ATHETGTSSDSTSSVLGPHTDNMICAVSKASLDSVFSDKLHSKYELQQIKHEPIASVRIKEEPVNVNIPEKTTALNNMDGKNV-----------KAKLDHVQFAEFKIDMDSKFENSNKDLKEELCPGNLS-LVDTRQHSSAHSNQDKKDDDILC-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B7YZX6-1", "uniprot_id": "B7YZX6_DROME", "id": "B7YZX6-1", "name": "Round spermatid basic protein 1-like protein", "aln": "MENTRGGENNVELANGGKESTGNVRKPEKKPLEGAVGASKQRETPEKGVNKASAVENNNANARGNASPTTTSAQREATTTITPVEPTAAATTTNGNTLPTQQQQQLQSGDGNANNPTTNARIMLAAAEEEQAVASSVATTAGAPTAATTTATTTALADTTKTSTSTDEKTGKVKRNSQNTNPMSTNVICTPTHSPTPPTEERNHKRKKRDRERDEDKNRRSNNHNSSSKDRDKDRDRDKERDKERDRERERDRNRESSSKSSKEAEHKSSSSRSKEKYHRSDRDREREKERDREKIPSSSSSSSSHSNRRRSSDSSRSSQNSSFKSKDPGADPVLPQAVVAALEKQIKVEEVIKKEPVETKQEVDTEPTPVLSNLIKTEAEIKTESTEKPNKPLVNGEAIAKTRDEVSRQLNFGDKVSNSKLMPSPAPKSSSGSNSTASNHSSSQSSSSRKSYLSSSSSSSSSNHHKSSSSSSSRHSSSTSRECSKCYKRSKIRRTSVGVQCLQHAPATGPWQTVQSLPPRPNRKPPAGLENLKYGCYFQVEQYPNGGASIVHLYQHEIDALSPDEMEELVDEFFEVCFAEDEQGYAHHVMGIVHDAARYLPDLLEHMAENYSTLTVKAGVLGRNSDIETCTMSQYNEQVVRNYCQGTFRYGPLHQISLVGKVHEEVGGYFPDLLGRIEMNPFLRKTMPWACNSILQTDPRQ-SNDGPILWIRAGEQLVPTAELNSKTPLKRQRTRINELRNLQYLPRLSEARETMIEDRTKAHADHVGHGHERITTAAVGILKAVHCGQTYSQNRITKDVVAFAAQDFNTMVEMLQLDLHEPPISQCVQWIEDAKLNQLRREGVRYARIQLCDNDIYFLPRNIIHQFRTVTAVTSVAWHLRLRQYYPGQEVINEKNNPVLAETPHYKEKQTILPNPISHDECG-KKTPSKRAHDGRTKKKLIDLDGKERRSSESSIDEHPAAGSSSPSQNQENNSNSSSQSGASGVSTPKKKSSKEDSKIDMRKMVLEHKYKLTKAAVTETPEKEKLKKDKDKEKSRGKDRDKEKERGKEKEKEKEKKNDTPKKHATPAKSSLSEPSPAKIPKLNNDTAPATALPLKSTPSSAPPTCTLPVAAPPILSGLPPPLVPQTPFIDRLNQKEPEIKIEVKIVSDSKSDISTSNPVVSTTAPPPPPPPDPVEDVGNELIVESTPQLIVDHEEEVSEVCSEEIVEMDIPIPKEPVPAAAFTSLPNTPSPLISAHSTLATAPIPKSFLHPPVPIVAAPAPPPPSQIVKVVLPGSLTPLTRMSVVLPPLPPLPPSRTSAPPPPPPPPSTKSSAITMPISAPVSTLKPTYKTINLPSHKIIIAGSAAGSRVSMAKGTSKRPDLLGSIIASMDKPAGSGPNSNSSSSTSSATTNSSLSSYAGSNNSF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . ...: :::*. .: . ...: : .:.: *:::: : :*:... .. :: *: .*..: : .. .**.: ::. . : .: .. :.. .: .. :...:: : .* *. * * .::*:**: * : . . .* . .. .*.* * : .::*:* :*:.:.*: .. . *: * :: : . :*.. :.:* .:.: *.:...* *: . : :*: : :. * : . :* : . *. *.: :.* .*. ...* .::* ... ..: :: *:.* : :::*: *****:::* * *:. *** **..:.:**. : *:*:*.. *.:***:**.** ****:*:::: *:.. .** :**:: **** ***::: ** *.*.:**:* **::****** *.****.***::*. :* .***: *:**. * *: :.*: *:****:*:*.***::*.*:: *:*:**:** **::******* **.** ::****:*****:*:*.** ******:*******: .* *:****:.* *:** :*: :********:******::***********:******* ******:***::***:**:** *:***:**: *:. : . :.. . ..::* . .::. . . ..: .* : *.. *.*.* . . ** :... *: : :: :: :: :: :: :.* .:. *..: .:::. . ", "identical_positions": 254, "similar_positions": 318, "identity": "18.04%" }, { "cls_id": "homologset.agr.RGD:1308749", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "O35652-1", "uniprot_id": "LHX8_MOUSE", "id": "O35652-1", "name": "LIM/homeobox protein Lhx8", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------MYWKSDQMFVCKLEGKEVPELAVPREKCPGLMSEECGRPAALAAGRTRKGAGEEGLVNPEGAGDEDSCSSSAPLSPSSSPQSMASGSVCPPGKCVCSSCGLEIVDKYLLKVN-DLCWHVRCLSCSVCRTSLGRHTSCYIKDKDIFCKLDYF--------RRYGTRCSRCGRHIHSTDWVRRAKGNVYHLACFACFSCKRQLSTGEEFALVEEKVLCRVHFDCMLDNLKREVE--------------------------------NGNGISVEGALLTEQDVNHPKPAKRARTSFTADQLQVMQAQFAQDNNP---------------DAQTLQKLAERTGLSRRVIQVWFQNCRARHK----KHVSPN-HSSSAPVTAVPS---------------------------------------------SRLSPPMLEEMAYSAYVPQ--DGTMLTALHSYMDAH-------QQLLD-SSPCYPIQ------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3V6V6-1", "uniprot_id": "G3V6V6_RAT", "id": "G3V6V6-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------MYWKSDQMFVCKLEGKDVPELAVPREKCPGLMSEECGRPAALAAGRTRKGAGEEGLVNPEGAGDEDSCSSSAPLSPSSSPQSMASGSVCPPGKCVCSSCGLEIVDKYLLKVN-DLCWHVRCLSCSVCRTSLGRHTSCYIKDKDIFCKLDYF--------RRYGTRCSRCGRHIHSTDWVRRAKGNVYHLACFACFSCKRQLSTGEEFALVEEKVLCRVHFDCMLDNLKREVE--------------------------------NGNGISVEGALLTEQDVNHPKPAKRARTSFTADQLQVMQAQFAQDNNP---------------DAQTLQKLAERTGLSRRVIQVWFQNCRARHK----KHVSPN-HSSSAPVTAVPS---------------------------------------------SRLSPPMLEEMAYSAYVPQ--DGTMLTALHSYMDAH-------QQLLD-SSPCYPIQ------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q68G74-1", "uniprot_id": "LHX8_HUMAN", "id": "Q68G74-1", "name": "LIM/homeobox protein Lhx8", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQILS---------------------RCQGLMSEECGRTTALAAGRTRKGAGEEGLVSPEGAGDEDSCSSSAPLSPSSSPRSMASGSGCPPGKCVCNSCGLEIVDKYLLKVN-DLCWHVRCLSCSVCRTSLGRHTSCYIKDKDIFCKLDYF--------RRYGTRCSRCGRHIHSTDWVRRAKGNVYHLACFACFSCKRQLSTGEEFALVEEKVLCRVHYDCMLDNLKREVE--------------------------------NGNGISVEGALLTEQDVNHPKPAKRARTSFTADQLQVMQAQFAQDNNP---------------DAQTLQKLAERTGLSRRVIQVWFQNCRARHK----KHVSPN-HSSSTPVTAVPP---------------------------------------------SRLSPPMLEEMAYSAYVPQ--DGTMLTALHSYMDAHSPTTLGLQPLLPHSMTQLPISHT----------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8IRC7-1", "uniprot_id": "AWH_DROME", "id": "Q8IRC7-1", "name": "LIM/homeobox protein Awh", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKTELRS-------------CAACGEPISDRFFLEVG-GCSWHAHCLRCCMCMCPLDRQQSCFIRERQVYCKADYS--------KNFGAKCSKCCRGISASDWVRRARELVFHLACFACDQCGRQLSTGEQFALMDDRVLCKAHY-------LETVE--------------------------------GGTTSSDEG---CDGDGYHKSKTKRVRTTFTEEQLQVLQANFQIDSNP---------------DGQDLERIASVTGLSKRVTQVWFQNSRARQK----KHIHAGKNKIREPEGSSFA---------------------------------------------RHINLQLTYSFQNNAQNPMHLNGSKAGLYPTHESSMD------ELSQDSSVHCMPSEV-----------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36166-1", "uniprot_id": "PXL1_YEAST", "id": "P36166-1", "name": "Paxillin-like protein 1", "aln": "MYNSIYGSPFPKINPKVRYKTALERAGFDTKPRNPFSSQRNASTGSLQASVKSPPITRQRNVSAAPSVPVTMKSAYTASSKSAYSSVKGESDIYPPPVLENSERRSVTPPKNSNFTSSRPSDISRSISRPSERASQEDPFRFERDLDRQAEQYAASRHTCKSPANKEFQAADNFPFNFEQEDAGNTEREQDLSPIERSFMMLTQNDTASVVNSMNQTDNRGVLDQKLGKEQQKEESSIEYESEGQQEDENDIESLNFEPDPKLQMNLENEPLQDDFPEAKQEEKNTEPKIPEINVTRESNTPSLTMNALDSKIYPDDNFSGLESSKEQKSPGVSSSSTKVEDLSLDGLNEKRLSITSSENVETPYTATNLQVEQLIAQLDDVSLSRNAKLDMNGNCLNAVDRKASRFKKSSAYLSGYPSMDIPVTQQTSIVQNSNTNLSRQTILVDKGDVDEDAPSESTTNGGTPIFYKFKQSNVEYSNNEGMGSQETFRTKLPTIEALQLQHKRNITDLREEIDNSKSNDSHVLPNGGTTRYSSDADYKETEPIEFKYPPGEGPCRACGLEVTGKRMFSKKENELSGQWHRECFKCIECGIKFNKHVPCYILGDEPYCQKHYHEENHSICKVCSNFIEGECLENDKVERFHVDCLNCFLCKTAITNDYYIFNGEIPLCGNHDMEALLKEGIDNATSSNDKNNTLSKRRTRLINFN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . .. . : * : . : : . : : .:: . :: : *. .* : * :.. : : . :*.. : :* ::: *.: . *: ... * : . * . :: . . * :. *::. ..* :. *:: . *.* ..: : ::.:. : :: . * . :: : . : : .. .. : . . ", "identical_positions": 17, "similar_positions": 91, "identity": "2.41%" }, { "cls_id": "homologset.agr.RGD:1308750", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q562C7-1", "uniprot_id": "PUM3_RAT", "id": "Q562C7-1", "name": "Pumilio homolog 3", "aln": "MEVKGKKKITGKSPQTSQGKNKFHKNSESSSAKAFP-RKAAKEGGPKVTSKNFEKGATKPGKKRVKQFKNKPQG-------GKGPKDKFQKANKFNKKRKFQPDGKSDESAAKKPKWDDFKKKKKELKQNRQLSDKTNYDVVVRAKHIWESLRRKD--CDKEKRVKLMSDLQKLIQGKIKTIAFAHDSTRVIQCLIQYGSEEQRKWAFEELQGDLVELSKAKYSRNIVKKFLMYGSKPQIAEIIRSFKGHVRKMLRHSEASAIVEYAYNDKAILEQRNMLTEELYGNTFQLYKSAD-HPTLEKVLEVQPGKLELILDEMKQILTPMAQKEAVIKHSLVHKVFLDFFTYAPPKLR--SELIEAIREAVVYLAHTHDGARVAMHCLWHGTPKDRKVIVKTMKTYVEKIANGQYSHLVLLAAFDCIDDTKLVKQIIISEVISSLPSIVNDKYGRKVLLYLLSPRA----PAHLVPEIIQLLQKGDGNAHSKKDTAIRRRELLESISP------------------------ALLSYLQGHTREVVLDKSVCVLVS-------DILGSATGDAQPAMDAIAGLAAEELYPG--------------------------GKDGELHIAEHPAGHLVLKWLIEQDKK----------------------------IKENGKEG--CFAKTLVECVG-MKNLKSWASINRGAIVLSSLLQSCDQDVVNKVKAGLKTLIPTLEKTKSTSKGIQTLLEKLTA--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BKS9-1", "uniprot_id": "PUM3_MOUSE", "id": "Q8BKS9-1", "name": "Pumilio homolog 3", "aln": "MEVKGKKKFTGKSPQTSQGKNKFHKNSESSSSKTFP-RKAVKEGGPKVTSKNFEKGATKPGKKGVKQFKNKPQG-------GKGPKDKFQKANKFSKKRKFQPDGESDESGAKKPKWDDFKKKKKELKQSRQLSDKTNYDIVVRAKHIWESLRRKD--CDKEKRVKLMSDLQKLIQGKIKTIAFAHDSTRVIQCFIQYGNEEQRKQAFQELQGDLVELSKAKYSRNIVKKFLMYGSKPQVAEIIRSFKGHVRKMLRHSEASAIVEYAYNDKAILEQRNMLTEELYGNTFQLYKSAD-HPTLDKVLELQPAKLELIMDEMKQILTPMAQKEAVIKHSLVHKVFLDFFTYAPPKPR--SELIEAIREAVVYLAHTHDGARVAMHCLWHGTPKDRKVIVKTMKTYVEKVANGQYSHLVLLAAFDCIDDTKLVKQIIISEIISSLPSIVNDKYGRKVLLYLMSPRD----PAHTVPELIELLQKGDGNAHSKKDTAIRRRELLESISP------------------------ALLSYLQGHTQEVVLDKSACVLVS-------DMLGSATGDVQPAMDAIASLAAAELHPG--------------------------GKDGELHVAEHPAGHLVLKWLLEQDKK----------------------------MKESGKEG--CFAKTLVERVG-MKNLKSWASINRGAIILSSLLQSCDQEVVNKVKGGLKPLIPTLEKNKSSSRGIQTLLEKLTA--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15397-1", "uniprot_id": "PUM3_HUMAN", "id": "Q15397-1", "name": "Pumilio homolog 3", "aln": "MEVKGKKQFTGKSTKTAQEKNRFHKNSDSGSSKTFPTRKVAKEGGPKVTSRNFEKSITKLGKKGVKQFKNKQQG-------DKSPKNKFQPANKFNKKRKFQPDGRSDESAAKKPKWDDFKKKKKELKQSRQLSDKTNYDIVVRAKQMWEILRRKD--CDKEKRVKLMSDLQKLIQGKIKTIAFAHDSTRVIQCYIQYGNEEQRKQAFEELRDDLVELSKAKYSRNIVKKFLMYGSKPQIAEIIRSFKGHVRKMLRHAEASAIVEYAYNDKAILEQRNMLTEELYGNTFQLYKSAD-HRTLDKVLEVQPEKLELIMDEMKQILTPMAQKEAVIKHSLVHKVFLDFFTYAPPKLR--SEMIEAIREAVVYLAHTHDGARVAMHCLWHGTPKDRKVIVKTMKTYVEKVANGQYSHLVLLAAFDCIDDTKLVKQIIISEIISSLPSIVNDKYGRKVLLYLLSPRD----PAHTVREIIEVLQKGDGNAHSKKDTEVRRRELLESISP------------------------ALLSYLQEHAQEVVLDKSACVLVS-------DILGSATGDVQPTMNAIASLAATGLHPG--------------------------GKDGELHIAEHPAGHLVLKWLIEQDKK----------------------------MKENGREG--CFAKTLVEHVG-MKNLKSWASVNRGAIILSSLLQSCDLEVANKVKAALKSLIPTLEKTKSTSKGIEILLEKLST--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O61345-1", "uniprot_id": "PENG_DROME", "id": "O61345-1", "name": "Protein penguin", "aln": "-MVSSEPKGPANVANTASPLKAHESSGKRANGQKFKPGGAGGARKFDKFGGGAGKSFVKPGAGGAKKFDKSGPGGFKKFDKSGATGDKRLGGNKFRGKPQTQPQAPAE---GEKQDWNKFKKEKKDLKLKR-KSAKDTYEISKEANQIHEKLRCRR--TENKDKLVEQIYKVLNVGDTISKVVKAHDTARVIQSMLKYASPALRAEISEKLLPFTVEMCQSKYAQFCVQRMLKYGAPATKAKLVDSLYGHIVRLAGHSIGSGLLDSMY-QSATPNQRIYMRQEFYGDLYRKAKDSN-VKTLSDTYKEATNMKASILGSVKANLDHVAN-KQLVDSALVHAVMLEYLRACDEDEEKLEETVTAFAALVPHMLSTKEGSEAAVICFYKSTPKNRRAIIKNIKEHLLKIANHEHGHVFLISLLNALDDTKATKKAIYDHLHGDLKALMSSPYGRRVIQWLVAPGD----TTCFHPEFIRTVEEG--LAFGKKEKELRRKEILEQIEAPIAQSIAEDAAFWLSNSHIGLVTGDILNHIQGESYEKAASALAQVVVQPEWRISADAAGPQPQDKKKPHNDVEAIIAQATKQRRKLLYVESSSDDEDEDEDEDEESDDEGDEKEQKEAAADDAEPKVKKAKKEPKKPKAKEEEPAAPLVSGIEEAGMHIVLKKILKNDGKREGTPFSQQLLQNLS-SDVLKAWLGVNRACFVLLKLVEECPALLDDCKKAIAAERSLSQILADRKTPGAKLLAAKLDIGK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04373-1", "uniprot_id": "PUF6_YEAST", "id": "Q04373-1", "name": "Pumilio homology domain family member 6", "aln": "-----MAPLTKKTNGKRSAKEVSHSEKKLAKKPRISIDSSDEESELSKKEDAVSSSSDDDDLDDLSTSDSEAEE--------EADELDISDDSEEHENENEEKEGKDKSEGGENGNHTEQRKLLKERKMQR-----KSGTQVQQIKSVWERLRVKTPPLPKQIREKLSNEIWELSKDCISDLVLKHDASRIVQTLVKYSSKDRREQIVDALKGKFYVLATSAYGKYLLVKLLHYGSRSSRQTIINELHGSLRKLMRHREGAYVVEDLFVLYATHEQRQQMIKEFWGSEYAVFRETHKDLTIEKVCESSIEKRNIIARNLIGTITASVE-KGSTGFQILHAAMREYVKIANEKEIS--EMIELLHEQFAELVHTPEGSDVACTLVARANAKERKLILKALKNHAEKLIKNEYGNIVFITILNCVDDTVLVFKTFSPTVKEHLQEFIIDKFGRRPWLYILLGLDGKYFSPIVKNELLRYIELS--KATSKKDPLQRRHELLSKFAP------------------------MFLSTISKDYSSILTENLGCQFIAEVLIN--DELYAQLNEKDQEKYQQVLNNILTTFKG--------------------------DITEEEHPIHRAFSTRLLKALIQGGKWNNKEKK-------------------VIPLKNVQGLG-VPFAEKLYDEIIDSSNLLEWINNADSSFTIVALYETLKDQKEGKPFLKDLRGVQSKITTDESNKGSQLLAKLLK---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . . : ... . .. : . .. . . . ... . . .: : : : :. . .:: . . :* *: * .* . . : : * ** : :: : . *. :. **::*::* ::*.. * : * :. : *.: : ::* **: . :: .: * : :: * .: ::: : * :** : :*::*. : :.:. *:... : * .: : .: : ::* .: ::. . . * : : . : * :*: .* . :...*:*: *:* :* : *: : ::.::.::: ::.:*** . : : : * :: . :**: ::: .. *::. :: . * .**: **:*:*..: . :*. :. . . . .: * . : . . * : . :* : * :*: *:: * : : . * * . ..: : * : . : . .. * : * * ", "identical_positions": 67, "similar_positions": 210, "identity": "8.89%" }, { "cls_id": "homologset.agr.RGD:1308751", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZJV2-1", "uniprot_id": "D3ZJV2_RAT", "id": "D3ZJV2-1", "name": "", "aln": "------------------------------MTPIFLLATLCLGMISAAPTHDPSFDTVWEEWKTKHGKTYN-TNEEGQKRAVWENNMKMINLHNEDYLKGKHGFSLEMNAFGDLTNTEFRELMTGFQG--QKTKMMK-------VFPEPFLGDVPKTVDWRKHGYVTPVKNQGPCGSCWAFSAVGSLEGQVFRKTGKLVPLSEQNLVDCSWSHGNKGCDGGLPDFAFQYVKDNGGLDTSVSYPYEALNGT-CRYNPKYSAAKVVGFMSIPP-SENALMKAVATVGPISVGIDIKHKSFQFYKGGMYYEPDCSSTNLNHAVLVVGYG---EESDGRKYWLVKNSWGRDWGMDGYIKMAKDWNNNCGIASDASYPIV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q623-1", "uniprot_id": "E9Q623_MOUSE", "id": "E9Q623-1", "name": "", "aln": "------------------------------MTPVFLLATLCLGVVSAAPAHDPSLDAVWEEWKTKHRKTYN-MNEEAQKRAVWENNMKMIGLHNEDYLKGKHGFNLEMNAFGDLTNTEFRELMTGFQS--MGHKEMT-------IFQEPLLGDVPKSVDWRDHGYVTPVKDQGHCGSCWAFSAVGSLEGQIFRKTGKLVPLSEQNLMDCSWSYGNVGCNGGLMELAFQYVKENRGLDTRESYAYEAWDGP-CRYDPKYSAVNITGFVKVPL-SEDALMNAVASVGPVSVGIDTHHHSFRFYRGGTYYEPDCSSTNLDHAVLVVGYG---EESDGRKYWLVKNSWGEDWGMDGYIKMAKDRDNNCGIATYAIYPTV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P07711-1", "uniprot_id": "CATL1_HUMAN", "id": "P07711-1", "name": "Procathepsin L", "aln": "------------------------------MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYG-MNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQN--RKPRKGK-------VFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEES-CKYNPKYSVANDTGFVDIPK-QEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NEU9-1", "uniprot_id": "A0A8M1NEU9_DANRE", "id": "A0A8M1NEU9-1", "name": "", "aln": "-------------------------------MMFALLVTLCISAVFAASSIDIQLDDHWNSWKSQHGKSYH-EDVEVGRRMIWEENLKKIEQHNFEYSYGNHTFKMGMNQFGDMTNEEFRQAMNGYKHDPNRTSQGP-------LFMEPSFFAAPQQVDWRQRGYVTPVKDQKQCGSCWSFSSTGALEGQLFRKTGKLISMSEQNLVDCSRPQGNQGCNGGLMDQAFQYVKENKGLDSEQSYPYLARDDLPCRYDPRFNVAKITGFVDIPRGNELALMNAVAAVGPVSVAIDASHQSLQFYQSGIYYERACSSSRLDHAVLVVGYGYQGADVAGNRYWIVKNSWSDKWGDKGYIYMAKDKNNHCGVATTASYPLM", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q95029-1", "uniprot_id": "CATL1_DROME", "id": "Q95029-1", "name": "Cathepsin L1", "aln": "MNHLGVFETRFRPRTRHKSQRAQLIPEQITMRTAVLLPLLALLAVAQAVSFADVVMEEWHTFKLEHRKNYQDETEERFRLKIFNENKHKIAKHNQRFAEGKVSFKLAVNKYADLLHHEFRQLMNGFNYTLHKQLRAADESFKGVTFISPAHVTLPKSVDWRTKGAVTAVKDQGHCGSCWAFSSTGALEGQHFRKSGVLVSLSEQNLVDCSTKYGNNGCNGGLMDNAFRYIKDNGGIDTEKSYPYEAIDDS-CHFNKGTVGATDRGFTDIPQGDEKKMAEAVATVGPVSVAIDASHESFQFYSEGVYNEPQCDAQNLDHGVLVVGFG---TDESGEDYWLVKNSWGTTWGDKGFIKMLRNKENQCGIASASSYPLV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* :.: : : . * :* * : * * : ::::* : * ** : *: *.: :* :.*: ***: *.*:: * .* *: **** :* **.**:* *****:**:.*:**** ***:* *:.:*****:*** ** **:*** : **:*:::* *:*: **.* * : *::: .. ** .:* .* : :***:***:**.** *.*: ** * * * *.: ::*.*****:* : .. **:*****. ** *:: * :: *:**:*: : ** :", "identical_positions": 121, "similar_positions": 86, "identity": "32.27%" }, { "cls_id": "homologset.agr.RGD:1308753", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GLX4-1", "uniprot_id": "A0A8I6GLX4_RAT", "id": "A0A8I6GLX4-1", "name": "Disks large homolog 5", "aln": "MEPQRRELLAQCQQSLAQAMTEVEAVLGLLEAAGALSPGERRQLDEEAGG--AKAELLLQLLLAKEQD---HFQDLRAALEKTQPHLLPILYLNGVVGPPQSTEGAGSTYSVLSIMPSDSESSSSLSSVGTTGKAPSPPPLLTEQQANDKVENLSIQLRLMTRERNELRKRLAFATHGATFDK---------RPYHRLNPDYERLKIQCVRAMSDLQSLQNQHTNALKRCEEVAKETDFYHTLHSRLLSDQTQLKDDVDMLRRENGKLRRERNLLQQSWEDMKRLREEDQKEIGDLRAQQQQVLKHNGSSEILNKLYDTAMDKLEVVKKDYDALRKR--YSEKVAMHNSDLSRLEQLGEENQRLQKQTEMLTQQRDTAIQLQHQCALSLRRFETIHHELSKATAQNKDLQWEMELLQSELTELRSKQVKTAKESEKYKEERDAVYSEYKLIMSERDQVISELDKLQTEVELAESKLKSSTSE-KKAASEEVEALR-----------------------------------------------------------------------------QIKDTVTMDAGRANKEVEVLRKQCKALCQELKEALQEADVAKCRRDWAFRERDKIVAERDSIRTLCDNLRRERDRAVSELAEALRSLDDTRKQKNDVSRELKELKEQMECQLEKEARFRQLMAHSSHDSAIDTDSMEWETEVVEFVRET--EDIDLKALGFDMAEGVNEPCFPGDCGIFVTKVDKGSIADG---------RLRVNDWLLRINDVDLINKDKKQAIKALLNGEG-AINMVVRRRKSLGGKVVTPLHINLSGQKDSGISLENGVYAAAVVPGSPAAKEGSLAVGDRIVAINGIALDNKSLNECESLLRSCQDSLTLSLLKVFPQSSSWSGQNIFENIKDSDRMLSCRAHGPEVQAHNKRNLLQHNNSTQTDIFYTDRLEDRKELDHSGGSSSYLYKPFSGASSPASPQACPSTSERSLNSFRSDTSAERGYGLVDVQSQRPLLSFETEVGPCGTVGAPLDKIDPEGSNSGG--TWPKAVLGSTSGPEKLSVYKKPKQRKSIFDPNTFKRPQTPPKVDYLLPGLGLTHSPQPSKRADTPKGSLTPPKPPRRSDSIKFQHRLETSSESEATLVGSSPSTSPPSAPPPSMDPSEPMHASPPRKARVRIASSYHSEGDGDTSYLPVKKPCDEDLTSQKVDELGQKRRRPKSAPSFR--PKISPVVIPAQCLEEQDCAPVSGELSPEAQDWSPYTLGHASRPGNPLLYPNRPSVGTVPRSMTPSTTVSSILRNPIYTVRSHRVVPCGSPPVPRDAGSHSLSSSVQHQGRLSLDLSHRACSDYS----EMRASQGSNSLPSSARLGSSSNLQFKAERIKIPLTPRYPRSVMGSDRGSLSHSECS-----TPPRSPLNVDALSFCS-QPQTSASTLPRIAVNSSSHGERRKDR--------------------------PFVEEPRHVKVQKGSEPLGISIVSGEKGG-IYVSKVTMGSIAHQAGLEYGDQLLEFNGINLRSATEQQARLIIGQQCDTITILAQYNP-HIHQLNSHSRSSSHLDPAAAPHSTLQGSSAATPEHPSVIDPLMEQDEGPGT----------------------------------PPAKQSTPSSRIVG------DASKKTPEPR-----------IVFIKKSQLDLGVQLCGGNLHGVFVAEVEDDSPAKGPDGLVPGDLILEYGNLDMRSRTLEDVYVEMMKPKDSIRLKVQYRHEEFTRVKGLSGDSFYIRALYDRLAEV-EPELSFKKDDILYVDDTLPQGMFGSWMAWQLDENAQKIQRGQIPSKYVMDQEFSRRLSMSEVKDDN-TAKMLSAAARRSFFRRKHKHKRSGSKDSKDLLSLDTFSNDSIP----LFEDSVSLAYQRVQKVDCTSLRPVLILGPLLDVVKEMLVNEAPGKFCRCPLEVMKASQQAIERGVKDCLFVDYKRRSGHFDVTTVASIKEITEKNR-HCLLDIAPHAIERLHHMHIYPIVIFIRYKSAKHIKEQRDPVYLRDKVTQRHSKEQFETAQKIDQEYSRYFTGVVQGGALSSICTQILAMVSQEQSKVLWIPACPP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q9R9-1", "uniprot_id": "DLG5_MOUSE", "id": "E9Q9R9-1", "name": "Disks large homolog 5", "aln": "MEPQRRELLAQCQQSLAQAMTEVEAVLGLLEAAGALSPGERRQLDEEAGG--AKAELLLQLLLAKEQD---HFQDLRAALEKTQPHLLPILYLNGVVGPPQSTEGAGSTYSVLSIMPSDSESSSSLSSVGTTGKAPSPPPLLTEQQANDTVENLSIQLRLMTRERNELRKRLAFATHGATFDK---------RPYHRLNPDYERLKIQCVRAMSDLQSLQNQHTNALKRCEEVAKETDFYHTLHSRLLSDQTQLKDDVDMLRRENGKLRRERNLLQQSWEDMKRLREEDQKEIGDLRAQQQQVLKHNGSSEILNKLYDTAMDKLEVVKKDYDALRKR--YSEKVAMHNSDLSRLEQLGEENQRLQKQTEMLTQQRDTAIQLQHQCALSLRRFETIHHELSKATAQNKDLQWEMELLQSELTELRSKQVKTAKESEKYKEERDAVYSEYKLIMSERDQVISELDKLQTEVELAESKLKSSTSE-KKAASEEMEALR-----------------------------------------------------------------------------QIKDTVTMDAGRANKEVEILRKQCKALCQELKEALQEADVAKCRRDWAFQERDKIVAERDSIRTLCDNLRRERDRAVSELAEALRSLDDTRKQKNDVSRELKELKEQMECQLEKEARFRQLMAHSSHDSAIDTDSMEWETEVVEFERET--EDIDLKALGFDMAEGVNEPCFPGDCGIFVTKVDKGSIADG---------RLRVNDWLLRINDVDLINKDKKQAIKALLNGEG-AINMVVRRRKSLGGKVVTPLHINLSGQKDSGISLENGVYAAAVVPGSPAAKEGSLAVGDRIVAINGIALDNKSLNECESLLRSCQDSLTLSLLKVFPQSSSWSGQNIFENIKDSDRMLSCRAHGPEVQAHNKRNLLQHNNSTQTDIFYTDRLEDRKELGHSGGSSSFLHKPFSGSSSPVSPQACPSTSERSLNSFRSDTSAERGYGLVDMRSQRPLLSFETEVGPCGAVEVPLDKIDPEGSNSGG--TWPKAVLGSTSGPEKLSVYKKPKQRKSIFDPNTFKRPQTPPKIDYLLPGPGLTHSPQPSKR----VGSLTPPKPPRRSDSIKFQHRLETSSESEATLVGSSPSTSPPSAPPPSMDPSEPTHASPPRKARVRIASSYHSEGDGDTSYLPAKKPCDEDLTSQKVDELGQKRRRPKSAPSFR--PKISPVVIPAQCLEEQECVPAIGELSPEGQEWSPYSPGHASRHGNPLLYPNRPSVGTVPRSMTPGTTVGSILRNPIYTVRSHRVLPCGSPPVPRDAGSQSLSPSVQHQGRLSLDLSHRACSDYS----EMRASQGSNSLPSSARLGSSSNLQFKAERIKIPLTPRYPRSVMGSDRGSLSHSECS-----TPPRSPLNIDTLSSCS-QPQTTASTLPRIAVNPSSHGERRKDR--------------------------PFVEEPRHVKVQKGSEPLGISIVSGEKGG-VYVSKVTLGSIAHQAGLEYGDQLLEFNGINLRSATEQQARLIIGQQCDTITILAQYNP-HIHQLNSHSRSSSHLDPAATPHSTLQGSSAGTPEHPSVIDPLMEQDEGPGT----------------------------------PPAKQSASSTRSVG------DTTKKTPDPR-----------IVFIKKSQLDLGVHLCGGNLHGVFVAEVEDDSPAKGPDGLVPGDLILEYGSLDMRSRTVEDVYVEMLKPKDSLRLKVQYRHEEFTRVKGLPGDSFYIRALYDRLAEV-EPELSFKKDDILYVDDTLPQGVFGSWMAWQLDENAQKIQRGQIPSKYVMDQEFSRRLSMSEVKDDN-TAKTLSAAARRSFFRRKHKHKRSGSKDGKDLLALDTFSNDSIP----LFEDSVSLAYQRVQKVDCTSLRPVLLLGPLLDVVKEMLVNEAPGKFCRCPLEVMKASQQAIERGVKDCLFVDYKRRSGHFDVTTVASIKEITEKNR-HCLLDIAPHAIERLHHMHIYPIVIFIRYKSAKHIKEQRDPVYLRDKVTQRHSKEQFETAQKIDQEYSRYFTGVVQGGALSSICTQILAMVSQEQSKVLWIPACPP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TDM6-1", "uniprot_id": "DLG5_HUMAN", "id": "Q8TDM6-1", "name": "Disks large homolog 5", "aln": "MEPQRRELLAQCQQSLAQAMTEVEAVLGLLEAAGALSPGERRQLDEEAGG--AKAELLLKLLLAKERD---HFQDLRAALEKTQPHLLPILYLNGVVGPPQPAEGAGSTYSVLSTMPSDSESSSSLSSVGTTGKAPSPPPLLTDQQVNEKVENLSIQLRLMTRERNELRKRLAFATHGTAFDK---------RPYHRLNPDYERLKIQCVRAMSDLQSLQNQHTNALKRCEEVAKETDFYHTLHSRLLSDQTRLKDDVDMLRRENGQLLRERNLLQQSWEDMKRLHEEDQKEIGDLRAQQQQVLKHNGSSEILNKLYDTAMDKLEVVKKDYDALRKR--YSEKVAIHNADLSRLEQLGEENQRLLKQTEMLTQQRDTAIQLQHQCALSLRRFEAIHHELNKATAQNKDLQWEMELLQSELTELRTTQVKTAKESEKYREERDAVYSEYKLIMSERDQVISELDKLQTEVELAESKLKSSTSE-KKAANEEMEALR-----------------------------------------------------------------------------QIKDTVTMDAGRANKEVEILRKQCKALCQELKEALQEADVAKCRRDWAFQERDKIVAERDSIRTLCDNLRRERDRAVSELAEALRSLDDTRKQKNDVSRELKELKEQMESQLEKEARFRQLMAHSSHDSAIDTDSMEWETEVVEFERET--EDIDLKALGFDMAEGVNEPCFPGDCGIFVTKVDKGSIADG---------RLRVNDWLLRINDVDLINKDKKQAIKALLNGEG-AINMVVRRRKSLGGKVVTPLHINLSGQKDSGISLENGVYAAAVLPGSPAAKEGSLAVGDRIVAINGIALDNKSLNECESLLRSCQDSLTLSLLKVFPQSSSWSGQNIFENIKDSDKMLSFRAHGPEVQAHNKRNLIQHNNSTQTDIFYTDRLEDRKEPGPPGGSSSFLHKPFPGGPLQVCPQACPSASERSLSSFRSDASGDRGFGLVDVRGRRPLLPFETEVGPCGVGEASLDKADSEGSNSGG--TWPKAMLSSTAVPEKLSVYKKPKQRKSIFDPNTFKRPQTPPKIDYLLPGPGPAHSPQPSKR----AGPLTPPKPPRRSDSIKFQHRLETSSESEATLVGSSPSTSPPSALPPDVDPGEPMHASPPRKARVRIASSYYPEGDGDSSHLPAKKSCDEDLTSQKVDELGQKRRRPKSAPSFR--PKLAPVVIPAQFLEEQKCVPASGELSPELQEWAPYSPGHSSRHSNPPLYPSRPSVGTVPRSLTPSTTVSSILRNPIYTVRSHRVGPCSSPPAARDAGPQGLHPSVQHQGRLSLDLSHRTCSDYS----EMRATHGSNSLPSSARLGSSSNLQFKAERIKIPSTPRYPRSVVGSERGSVSHSECS-----TPPQSPLNIDTLSSCS-QSQTSASTLPRIAVNPASLGERRKDR--------------------------PYVEEPRHVKVQKGSEPLGISIVSGEKGG-IYVSKVTVGSIAHQAGLEYGDQLLEFNGINLRSATEQQARLIIGQQCDTITILAQYNP-HVHQLSSHSRSSSHLDPAGT-HSTLQGSGTTTPEHPSVIDPLMEQDEGPST----------------------------------PPAKQSS--SRIAG------DANKKTLEPR-----------VVFIKKSQLELGVHLCGGNLHGVFVAEVEDDSPAKGPDGLVPGDLILEYGSLDVRNKTVEEVYVEMLKPRDGVRLKVQYRPEEFTKAKGLPGDSFYIRALYDRLADV-EQELSFKKDDILYVDDTLPQGTFGSWMAWQLDENAQKIQRGQIPSKYVMDQEFSRRLSMSEVKDDNSATKTLSAAARRSFFRRKHKHKRSGSKDGKDLLALDAFSSDSIP----LFEDSVSLAYQRVQKVDCTALRPVLILGPLLDVVKEMLVNEAPGKFCRCPLEVMKASQQAIERGVKDCLFVDYKRRSGHFDVTTVASIKEITEKNR-HCLLDIAPHAIERLHHMHIYPIVIFIHYKSAKHIKEQRDPIYLRDKVTQRHSKEQFEAAQKLEQEYSRYFTGVIQGGALSSICTQILAMVNQEQNKVLWIPACPL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32T3B5-1", "uniprot_id": "A0AB32T3B5_DANRE", "id": "A0AB32T3B5-1", "name": "", "aln": "MEPKHKELLHQCHQNLLESITDADRLIELLSKSGSLSEQEAFELDQNCSSSAEKVEQLLKMLMNKQSD---HFLELCVALEKTYPHLYSALFSN---GGGPADHHSGSTYSVLSTMPSDSESSSSLSSVGTK-ASSPPPALSDTRPASDSLDTILFQLKQVTRERDELRKRLALASPGTTFDD--------CRPNSKPGHDYERLKTQCTKAMADLQSLQNQHTKTLKRCEEAVKEADYYHIQHSRLLSEQTQLKEEMEVLKRENTKLTREHNHLKQSCEELRRLHSEDQREVADMRLQQQQVIRENGSSEVLNKLYDTAMDKLEGVKKEYDVLSKR--YSEKVSSHNTDLSRLEQVEEENRRLQKQIDALLKQRDTAIQYQQQWSTSMRRFDSVQQELNKASAQNKELQREMERLQSEVTRYKNFQLKAVKDGEKYKEERDSVFNEYRLIMSERDQVIKEVDKLQTELEAAEARLKNTSSE-RMVASEELEALRQELNSSLVDRDRAICERNELLEKYCHEVKDKAEAQKELSQACKDIETVREERDVARKERTEAIIQRDQLLREYYQARQKQDSATLDMERANKEIDILRKQCEAMSQELKEAVQEAEVAKCRRDWAFQERDKIVAERESIRTLCDNLRRERDRAVSDLADALRNLDDMRKQRNDAARELKELKEKMESQLDKEARFCQLMAHSSHDSAIDTDSLEWETEVVEFEKDR--DDMDLKAMGFDIAEGVNDPYLPGDCGIFVSRVDKGSIADG---------RLRVNDWLLKINDVDLTNKDRKQVIKAVLNGGG-LINMVVRRRKSLGGRLVTSVHINLIGHKDAGIALEGGVFVAGIAPGSPAAREGSLTIGDRLIAINGIALDNKSLSECEALLRGGRDSLALSLMKFFPQSTSG--QNIFESLREAE-KSNGRIHLTDVHSRNSRNLKHNS-STQTDIYSCDTAGERRKTRSDAEESLFSERKVFP-ISTLHPNTLRPASELGPVRYSASAFQEVCY---------------TRSESVGPECVTLETTLEKKHSGGTWPKMVVGVAMTTDSPAQLSIYRSPKQRKSIFDADTFKRPDTPSKADYHGP-----QPLKA-------DSAPTPPTPPTRSDSFKFKHKHQGSSTSESTISAMSISEPK-----------------------QEDRNGNLYFSEGKVLSS--RKSCEEDIGRMWAEEPEVKRPRPKSAPALR--RRMTPQNIPLQSFQSYSNDGDSVEQR-EMLRSSPNRPHRHSVGFVPTSYNGTLPPNSAHRGLAPCSAVTAVMKNPVYMVRSHRVHTNNCPTVVSQINQQHTHPSPQHQGQLSLDLSQKRSTDYSESSRSSRASHGTNSLPSSARLGSSNNLQYRTERIKIPSTPRYPRSILGSDRGSLSHSECSSPSLITPPLSPLNLETSSFASSQSQGSISTLPRISVSPVPTEERRKDRSLYRNRSFLRIPLAARPKFCSLRSLRPYLEEPRNVMVHKGAEPLGISIVSGENGG-IFVSKVTGGSIAHQAGLEYGDQLLEYNGINLRNATEQQARLIIGQQCDTITIMAQYNP-HMYQLGNHSRSSSRLEP-VSTQSTPQGSGTATPDNHSTIDTLSEQDEGTLT----------------------------------PSSKQTTPTTSPNSFIRMPSESSKKVPEAR-----------LVTVRKTQVELGIQLCGGNLRGIFVERLEDDSPARGADAVVPGDMILEYGSVNMKNKTVEEAYLEMLKPAETVTLRVQHRLDEFNQVKGTPGDGFYIRALYDRVAET-ELDLSFKKDDILYVDDTLPNGNFGTWMAWQLDENAQKIQRGQIPSKFMMDQEFYRRHSMTELKDETGSSKTLSAAARRSFFRRKHKHKRSSSKDGKDVVALDAISTDSIP----FLDDCVSLAYQRVQKIDCTSPRPVLILGPLVDPVKDMLVKDSPGKFSRCVLEVMKASQQAIERGVKDFLFIDYKRRSGHFDVTTVASINEITDKDC-HCLLDIAPHAIERLHSVHIYPIVIFIRYKNAKQIKEQKDPIYLRDKVSQKHSKEQFEIAQKIEQDYSKFFTGIVQGGTFPYICTQIVTIVDQEQSKVLWTPLGSP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9QF19-1", "uniprot_id": "A0A8M9QF19_DANRE", "id": "A0A8M9QF19-1", "name": "", "aln": "MEAKHRELLEQWQQKFPESGTDVERLLELLAERGCLSAAERAEIRRSGGGGREKIRRLIHTLLEDQNQNQQRFQELCWALEKAQP-------------GDNQQHNTGSSCSVLSAMPSDSESSSSLSSV-----ASSPPAHLEKQVLSEKLEPLLSQLRQVTRERDDLRIRLALSLPGSTFDENTAAAADARRPSVKPGHDYEHMKLQCMKAMTDLQSLQNQHNKTLKRCEEAARDADYYHTLHARVVGEQTQLRDETEAVKQKYTQLLQQHTHMQQTCDELRHTHDSDQRELQDLRMQQQQVMRENGSSDLLNKLYDSALNKLEALKKEYEALRKR--YNEQTALHNADVSRLEQLEEEKRRLQ-------KQRDAALHFQQQYSGSMHRFESVQQELNKLSVHNEDLQRETERLQMENTRCKTLQLKAVKDAEKLKEERDSVLSEYRLIMSERDQVIKELEKLQSGLEAAEHKLKNTSSE-RRVAGEEMEALRQELNSALLDRDRAIREKNELLEKYCHEVQDKAETQKELSQACKDIEMVREERDVARKERTEAIIQRDQLLREYYQARQKQDSAALDMERVSKELEVLRKQCEAVQEELQEALQEAEVAKCRRDWAFQERDKIVAERESIRTLCDNLRRERDRAVSDLADALRNLDDLRKQKNDAVRELKELKECMDEQLEKEARFRQLMAHNSHDSAIDTDSLEWETETVEFQRST--DNMDLSALGFDISEGVSDPYLPGDYGIFVSKVDKGSIAEG---------RLRVNDWLLKINDVDLANKDRQQVIKAVFSGGGGVINMLVRRRKSLGGKTVTSVHLNLAGQKDCGVGLESGVFVSSVSPGSPAAKDASVCPGDRILNINGISLDNKPLSECENLLRSCRDSVSISLLKFFPQSVSV--QSISEIQRDGE-RNSN----TDPPPRPSR--------KPSSISTSSSISIRKET--------YSPEHVYR-PEPYHQICLHPK---RPLTFHPASPADNTQ---------------QRQRPTGGTWPKIIPVAMNTSDS------IPVAMATADSIPPLSIFKTPKKRKSIFDADVFKRPETLEYVKHTHT-----HSPQGSW-----TDTPAPPDPPKRSDSFKFKHKTQGSSASDSTVTAGSPPATP-----------------------VQESSS----ADADACVL--QDGCVNNT-----DPIELQRGRPKSAPAPR--RNLTPLKMPYT--QSFSHDEQSPEPV-DLVRFSPFRSNRHSSAFTAG------HSLTAPRALSPYPAVTAVMRNPVYTAWSHCVKTTNSASVPSHT---YTQVSPQHQGRWSVDLNHKRSAELFDNSRGS-GAHNTHSLPSSARQGLS---QYREQRIKIPSTPRYARSVHGSDRGSLSHSDCSSPSLVTPPLSPM--DSASYTSGQSQASGSTHSRLSVSPVPID-RRRDRCVLRNRSFLKLSRSQRSWFASLRTLRPFIEEPRYVTIPKGAEPLGISIVGGDNGG-IFVSKVTEGSIAQKHHLEFGDQLLEFNGVNLRNATEQLARLIIGQQCDTITILAQYNT-HMQQLGNHSRSSSRMESSLSSHSTP-----GTPDTHSNIDTLSEQDEGTMT----------------------------------PPSKQATPTSSP----------HRERAEPR-----------QVLLRKTPVDLGMRICGGNLTGVFVEDLEDG----GAHGLQPGDLILECNSVSMKSKTAEEVYLELLKPAENIVLRVQNRPQHFRRAKDTPGDGFYIRALFDHVGDS-EQELSFKKDDILYVDDTLPRGNFGYWLAWQLDENAQKLMRGHVPSKCMMDQDSQRRYSVTDGKDESGSGKTLSAAARRSFFRRKLKHKRSTSKDGRDAPAADAISTDSMP----YLEDCVSPAYQRVLKVESTNRRPVLILGPLVEPIKDMLLREAPGKYCRCLPEGMKAQQQAIERGVKDCLFIDYKRRSGHFDVTTVASIKEITEKDC-HCLLDIAPHAIERLHAVSIYPIVIFIRYRNAKQIKEQKDPVYLRDKVSQKHSKEQFESAQRIEQDYSKYFTGVVQAGALSNTCTQIMAIVDQEQNKVLWIPDGST", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VKG8-1", "uniprot_id": "Q9VKG8_DROME", "id": "Q9VKG8-1", "name": "", "aln": "-----MAKMASGDLSLTSTSSQEEESSEYVGYDNTLRPPSNSSGSTTAAN------------MSNNNG---PSKGVSSGVG-----------------VSGISGGNGANYDILQAQYKSALLELNTLRHQHANTKRRCDELATELTLYQEHYVADRNKFTDMVEESARFKRLLLETQNQQSQQ-------AQNGNSQVPPVGSGNPYYFGKTQGCDGSCSEKLAELKKERNMVAVEREKYKKSYIELEKDRNYYRERGDENQKLKVLLSQESKNVLSLTEELNQLLSEKDNVLQEHQKMSDDLVLANKEIERLKKDEQLARAEIKVLQLANADLKKRDLLKSRDSSWSKEFPSGKELEN-SKELEKLRKSLEKALSEVERSSQDAEEAKRVRDWAISQREKIVQERDSVKTLCDKMRHERDKAISDSLMAIRDSEKIKKQKDEAQKKIDLLKEQME--QQERQNLDSNASGSRRSFRPSSYEGEDLLEVELSGYEHT---------------------------------------------------------------------------SDLGIILDDSNKRKLVCGVTSSSPACGKLKINDVICKVNNLDCQSLSKRMVLDEIRACAPRSLLLVSRTRHS-KRHAYSVQLKTRDRDCPHGLQLDMGVFIAKIEQNSLAFYEPELDVGDRVLSINNKSMDSVQSIEEVMQLMNDPRSDGLNLFALKYVQDQLPPGMTTSSAQTDSIDSMQHVSSAGGGGGSGPSSATKHPSRFAEFFFRKLKFSKPGTPEDNFEQEHDDAIAALDSVLSENSSEKSKENLFNRKKRTKKEKEASKSMGTWPRTNISHENPTGTMRGNEKKRALMSLFTAGPINVDKDDELMGEVGVPEKQPAALIQDQLPPPLPPQMSKPLAHIRGSNGGAIKTHPNRNSNPVSSGVSALFPPGPPNGMPNTSYPTHPRHSLYGVTAEEINQKPIQRAPLMGANARVKMPSQERYGTRPHSNHRLSLN----------ITPSGDFYQPKTSGQQAQQQVMNASSTSAG-FGVGSGSMVGGTGPAAGEFPVRKQQVYDVFHPPPLPKNSSGSNMFMPLHPTRGSHPPPVGQ----------PPDVVSLKSQNSIESILSAKSPAISEYGMYAKRHVP-----------------------QAVRHVPKYPSDSESIGSGVHGGYGGFLQSNHMPGNRHTQLFPTFGPGGRGNRRSSPLTLPSPPPQQQLQQLPAATAPHDSVGIPTDLDYHPHHH----------TQTNAMPHPHPHPHAPYLDYGHGLGIGPYMGVGGGVSGVGGAIYEGGTFPRKKDNQRLRIPSNPSVASKSSSMVKNSSGSIDHHYVTSTGPVSGGSMSASSSDRAPMSLMSSSIHNSYGANIAGGNGTGSS--------------IGVGGGGGGGSGRGSPMPQVHVEVLSHGGGGSGK-----------------RNSNVPADFLCPGDLRRVTIDKRDKSLGITIQCNNNGGGIFVSTVADKSTAMRAGLQVGDQLLEVCGINMRAATQEIAANVLRQCGDSFTMLVQYNPEKFPSIEYEGAHNLEPESPINHSGSPTPRNSPRPPARNSLFPLPMQPQAPSTRPGSRAPLSHQSIKDQSFTDSLENQSDISSSQDMPSSAATTTTTTASATSTVYDEEPKPSLPPPPASVPAETLRYVTLHMDKSKNLGIKLFGGNKVGIYVHDVAVGSPS-DHAGIRKGDQILEYNGVDLSGVTAEQAANEISKLTDTVTMLVQNKLHTLKQIKDEPGDSFYIRVGFDRTGELNEDDLRFVKDEVLYVDNTVFNGTFGLWRAWKLDAMGHRKECGIIPSQMKVEEELR---SGEVVDCDTGTARRGSTSARRSFFRRK-KNQRSSSRDSTEIASFSNTQLSFFPDLGLLNDDGGALSYQRVELLDSPIRRPVLIIGPLSECLMVRLTIDFSNLFKLCEVTAMDCSQEAMEEGLKENIFVDYRRRGNKFECTTVEAISNACKNDRRHCILDVSISAVERLQRLQIYPIVLLLRFKSAKQIRDIRD--FGTDKISAKAAKEMYERAMKLETDYKQYISAVIPGVSIKHMCTQIKDAVDKEQDKLLWVPVSSG", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . .: .: :: : : . * . . .. : .: : .: *:. .:*. ..: . . : : *.. ** : . :. . : . :: * .:: : *. : .. : : *: : .: ::. :: : :: * :: . : . :::.: ...:. : : : .:::: * . : *:* : * ::: :: * ** ..: : . :.. ::: : .:.* : . . : .:: : : : : .* ....:: : :: * . . .: : ::.** ::::* . .: *: .: : .* ::*:: . :. :: :: * . *:.. . . . * : . : .. . ::::.: :.: .*: *:* * * .. *:. .* . .: *. * : : * : :::: : * . : : .:.* ..:*:* : :: :. : : *. : ::. *:. . * : :*.... . * *. ::::: ... .. ..: : .. . .:: .. .. . . : : . .*:.. .: . ....: .. : :.. .:: . .* : ... : : . :* . . .. : .: : . . ..: . :. . . . . .. :: .:*.. : : .: :. ** ... .:: . .* : : : .:.. : : *. .*. * . :* :* :. : .. : .. * . . : . .: . . . :.: : : . .:. .: . : :.*:. . . :* :. . :. *:: .. . : .* . . . *. .:: *. . .: : * * : * :.***:* .::** ::**.*: * * : *: ****** *:*:* **:: * :: * *::*::.***. :. .: .. . . :. .: * . : .* * :.. * *.: :: : : . . .. :**::: *** *::* : . . .: ** *** ..:.: . * *:. *: * : : : ** : . : : *. .**.****. :*: .: * :* * **::****:*: .* ** * **:** .:: * :**: :::: * . :. : : *::********* *::** *:*. : : . . . :* :* : :**** ::.. ****::*** : : * : .. : * *...*:*:*.*:*: :*:**:**..:*: *** :*.: .:: **:**:: *:***: : *****::::::.**:*:: :* : **:: : :** :* * ::: :*.::::.:: . :: **** *.:**.*:** * . ", "identical_positions": 235, "similar_positions": 619, "identity": "11.03%" }, { "cls_id": "homologset.agr.RGD:1308754", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZM61-1", "uniprot_id": "D3ZM61_RAT", "id": "D3ZM61-1", "name": "Zinc finger protein 653", "aln": "MAERAPEP----------GAEAAAEEGAAGRKARGRPRLTESDRARRRLESRKKYDVRRVYLGEAHGPWVDLRRRSGWSDAKLAAYLISLERGQRSGRHGKPWEQVPKKPKRKKRRRRNVNCLKNVVIWYEDHKHRCPYEPHLAELDPTFGLYTTAVWQCEAGHRYFQDLHSPLKPLSDSEPDSDKVGNGLAAGSSDSSSSSSSSDSEEPPETQPAKAPAAAAAVTPSSPTGSSGLITQEGVHIPFDVHHVESLAEQGTPLCQNPAGSGPEALETVVCVPVPMQVGTGPGTLFENMPQEALGEVVASCPVSGMVPGSQVIIIAGPGYDALTAEGIHLNVAAGSGTPSSSLGEEVSCAMMEGVAAYTQTEPEGTQHSTMDTTSIASIETKKDTAPCHPVEKEDLYMLK-EEKEDSVAPELAELAATVPENTEAEAEVDGEELDSSEMSAIIYEIPKEPEKRRRSKRSRVMDADGLLEMFHCPYEGCSQVYVALSSFQNHVNLVHRKGKTKVCPHPGCGKKFYLSNHLRRHMIIHSGVREFTCETCGKSFKRKNHLEVHRRTHTGETPLQCEICGYQCRQRASLNWHMKKHTAEVQYNFTCDRCGKRFEKLDSVKFHTLKSHPDHKPA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6YND2-1", "uniprot_id": "ZN653_MOUSE", "id": "Q6YND2-1", "name": "Zinc finger protein 653", "aln": "MAERAPEPGAEAEAGA--GGEAAAEEGAAGRKARGRPRLTESDRARRRLESRKKYDVRRVYLGEAHGPWVDLRRRSGWSDAKLAAYLISLERGQRSGRHGKPWEQVPKKPKRKKRRRRNVNCLKNVVIWYEDHKHRCPYEPHLAELDPTFGLYTTAVWQCEAGHRYFQDLHSPLKPLSDSEPDSDKVGSGLVAGSSDSSSSGSSSDSEEPPETQPAKASAAAAALTPASPTGSSGLITQEGVHIPFDVHHVESLAEQGTPLCQNPAGSGPEALETVVCVPVPMQVGTGPGTLFENMPQEALGEVVASCPVSGMVPGSQVIIIAGPGYDALTAEGIRLNVAAGGGTPSSSLGEEVPCAMMEGVAAYTQTEPEGTQHSTMDTTSIASIETKK--------EKEDLYMLK-EEKEDSVAPELAELAATVPENAEAEAEVDGEELDSSEMSAIIYEIPKEPEKRRRSKRSRVMDADGLLEMFHCPYEGCSQVYVALSSFQNHVNLVHRKGKTKVCPHPGCGKKFYLSNHLRRHMIIHSGVREFTCETCGKSFKRKNHLEVHRRTHTGETPLQCEICGYQCRQRASLNWHMKKHTAEVQYNFTCDRCGKRFEKLDSVKFHTLKSHPDHKPT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96CK0-1", "uniprot_id": "ZN653_HUMAN", "id": "Q96CK0-1", "name": "Zinc finger protein 653", "aln": "MAERALEPEAEAEAEAGAGGEAAAEEGAAGRKARGRPRLTESDRARRRLESRKKYDVRRVYLGEAHGPWVDLRRRSGWSDAKLAAYLISLERGQRSGRHGKPWEQVPKKPKRKKRRRRNVNCLKNVVIWYEDHKHRCPYEPHLAELDPTFGLYTTAVWQCEAGHRYFQDLHSPLKPLSDSDPDSDKVGNGLVAGSSDSSSSGSASDSEESPEGQPVKAAAAAAAATPTSPVGSSGLITQEGVHIPFDVHHVESLAEQGTPLCSNPAGNGPEALETVVCVPVPVQVGAGPSALFENVPQEALGEVVASCPMPGMVPGSQVIIIAGPGYDALTAEGIHLNMAAGSGVPGSGLGEEVPCAMMEGVAAYTQTEPEGSQPSTMDATAVAGIETKK--------EKEDLCLLKKEEKEEPVAP---ELATTVPESAEPEAEADGEELDGSDMSAIIYEIPKEPEKRRRSKRSRVMDADGLLEMFHCPYEGCSQVYVALSSFQNHVNLVHRKGKTKVCPHPGCGKKFYLSNHLRRHMIIHSGVREFTCETCGKSFKRKNHLEVHRRTHTGETPLQCEICGYQCRQRASLNWHMKKHTAEVQYNFTCDRCGKRFEKLDSVKFHTLKSHPDHKPT", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***** ** *.****************************************************************************************************************************************************************:*******.**.*********.*:*****.** **.**.***** **:**.*******************************.****.**************:***:**.:****:*************:.************************:**:***.*.*.*.*****.*****************:* ****:*::*.***** ***** :** ****:.*** ***:****.:*.***.******.*:************************************************************************************************************************************************************************************:", "identical_positions": 556, "similar_positions": 43, "identity": "88.82%" }, { "cls_id": "homologset.agr.RGD:1308755", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GMR5-1", "uniprot_id": "A0A8I6GMR5_RAT", "id": "A0A8I6GMR5-1", "name": "RNA-binding protein 25", "aln": "MDRQRKEGLCQLLWTGAVRMSFPPHLNRPPMGIPALPPGIPPPQFPGFPPPVPPGTPMIPVPMSIMAPAPTVLVPTVSMVG-KHLGARKDHPGLKLKENDENCGPTTTVFVGNISEKASDMLIRQLLAKCGLVLSWKRVQGASGKLQAFGFCEYKEPESTLRALRLLHDLQIGEKKLLVKVDAKTKAQLDEWKAKKKAN-GNARPETVTNDDEEALD------EETKRRDQMIKGAIEVLIREYSSELNAPSQESDSHPRKKKKEKKEDIFRRFPVAPLIPYPLITKEDINAIEMEEDK-RDLISREISKFRDTHKKLEEEKGKKEKERQEIEKE---------------------RRERERERERERERREREREREREREREKEKERERERERDRDRDRTKERDRDR--ERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERE--RERERERERERERE----KDKKRDREED--EEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQP----QIKQEPESEEEEEEKQEKEEK-----REEPVEEEEEPEQKPCLKPTLR------------PISSAPSVSSASGNATPNTPGDESPCGIIIPHENSPDQQQPEEHRPKIGLSLK---------LGASNSPGQP--------NSVKRKKLPVDSVFNKFEDEDSDDVPRKRKLVPLDYGE----------------------------------------------------------------------DDKNAAKGTVN-----------------------------------------------TEEKRKHIKSLIEKIPTAKPELFAYPLDWSIVDSILMERRIRPWINKKIIEYIGEEEATLVDFVCSKVMAHSSPQSILDDVAMVLDEEAEVFIVKMWRLLIYETEAKKIGLVK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B2RY56-1", "uniprot_id": "RBM25_MOUSE", "id": "B2RY56-1", "name": "RNA-binding protein 25", "aln": "-------------------MSFPPHLNRPPMGIPALPPGIPPPQFPGFPPPVPPGTPMIPVPMSIMAPAPTVLVPTVSMVG-KHLGARKDHPGLKLKENDENCGPTTTVFVGNISEKASDMLIRQLLAKCGLVLSWKRVQGASGKLQAFGFCEYKEPESTLRALRLLHDLQIGEKKLLVKVDAKTKAQLDEWKAKKKAN-GNARPETVTNDDEEALD------EETKRRDQMIKGAIEVLIREYSSELNAPSQESDSHPRKKKKEKKEDIFRRFPVAPLIPYPLITKEDINAIEMEEDK-RDLISREISKFRDTHKKLEEEKGKKEKERQEIEKE---------------------RRERERERERERERREREREREREREREKEKERERERERDRDRDRTKERDRDR--ERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERE--RERERERERERERERE--KDKKRDREED--EEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQP----QIKQEPESEEEEEEKQEKEEK-----REEPVEEEEEPEQKPCLKPTLR------------PISSAPSVSSASGNATPNTPGDESPCGIIIPHENSPDQQQPEEHRPKIGLSLK---------LGASNSPGQP--------NSVKRKKLPVDSVFNKFEDEDSDDVPRKRKLVPLDYGE----------------------------------------------------------------------DDKNATKGTVN-----------------------------------------------TEEKRKHIKSLIEKIPTAKPELFAYPLDWSIVDSILMERRIRPWINKKIIEYIGEEEATLVDFVCSKVMAHSSPQSILDDVAMVLDEEAEVFIVKMWRLLIYETEAKKIGLVK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49756-1", "uniprot_id": "RBM25_HUMAN", "id": "P49756-1", "name": "RNA-binding protein 25", "aln": "-------------------MSFPPHLNRPPMGIPALPPGIPPPQFPGFPPPVPPGTPMIPVPMSIMAPAPTVLVPTVSMVG-KHLGARKDHPGLKAKENDENCGPTTTVFVGNISEKASDMLIRQLLAKCGLVLSWKRVQGASGKLQAFGFCEYKEPESTLRALRLLHDLQIGEKKLLVKVDAKTKAQLDEWKAKKKASNGNARPETVTNDDEEALD------EETKRRDQMIKGAIEVLIREYSSELNAPSQESDSHPRKKKKEKKEDIFRRFPVAPLIPYPLITKEDINAIEMEEDK-RDLISREISKFRDTHKKLEEEKGKKEKERQEIEKE---------------------RRERERERERERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERE--REREREREREREREREREKDKKRDREED--EEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQP----QIKQEPESEEEEEEKQEKEEK-----REEPMEEEEEPEQKPCLKPTLR------------PISSAPSVSSASGNATPNTPGDESPCGIIIPHENSPDQQQPEEHRPKIGLSLK---------LGASNSPGQP--------NSVKRKKLPVDSVFNKFEDEDSDDVPRKRKLVPLDYGE----------------------------------------------------------------------DDKNATKGTVN-----------------------------------------------TEEKRKHIKSLIEKIPTAKPELFAYPLDWSIVDSILMERRIRPWINKKIIEYIGEEEATLVDFVCSKVMAHSSPQSILDDVAMVLDEEAEVFIVKMWRLLIYETEAKKIGLVK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V3Y5-1", "uniprot_id": "Q9V3Y5_DROME", "id": "Q9V3Y5-1", "name": "", "aln": "-------------------MSYPPRAPMPPFMNTAIPP---------------------PHIMQNMAKPPRSFRNSATISSQPTVYQRPPEPQPQFR------GPIITVFVGNISERVPEALLKRILNACGVVINWKRVS-------TFGFCEFDGPIAAMRAVRLLSEMEIDGKKLVAKVDAKNKVLIEDYKEQECKNGDRSNPVDEKTEDEFAIAQMHEFLEEHKHEFEGFDSSSRADLYGSANRNKKTRREEDIKMKVLSENTLEEEKRNLISSEIGKFRMRAEEDEHRKELEKEKEKEKLAASKEKERKKQREMERMSSTSKSGSSSTAAASSSSATATSSTPAADGADMSDKTDKESVAVVIKETVKESKESASSTGRKESSSAAIEITQKERRSDSKETRRRRSKSRSKDRERERERELRELRDKERERERDRERERERERNEMRERERNEMREREREREREREREEKLLKPVRDTWREKEMEDELRDRKKAEKKAREKEIAYQTRLTDWEVREKRKAKENEKYRLKELLRQEERETDAKRLKEFVEDYDDERDDSLYYRGRELQQRLAERVREADADSKDREKEAEELAELKSKFFSGEYENPSLEFEKARLEIEKLYEPRILINVNQEPPAAATSSVHQRKQAASAPGEDDEGQKQRQKSQQLDSYDPDMAGTNDDDSISNDDRASMADTASNASGVYAKNNNNDQSLSNSLSRHNSESRDSLAQIHTPTQSAILNDQESGHDAILPSATPPMTMPLISLTLGNNLKKKKIEATGVFVNDDDNDENINPKKRKLVPLDYDDNISNTTPSNHAASSGSGAANNSSSSNNNNSSSADRQSSAVSAATAAAAAVSQKIAQAFGGGSSGSGSGSGSGSNASGGKNNGGGSSSSSNNKHNSNSKHGKNEAAASAGSSADAAAANIKKDENGAKVYDEKRRHIKSIIDRIPTQKEELFNYKLDRNEIDSGLMERKIRPWINKKIIEYIGEPEPTLVDFICSKVLAGSPPQSILDDVQMVLDEEAEVFVVKMWRLLIYELDAKKSGLAGK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **:**: **: .*:** * *. ** .* : :.:: . : * .* : : ** *********:..: *::::* **:*:.****. :*****:. * :::**:*** :::*. ***:.*****.*. ::::* :: . ..:.* ..:** *: ** *:. : :..: .. : :.. : . :*.* : : .::. *: *.: : : : : ::** : *:*::* :: :: . .* *..::::*. ....:. .. : ::* :* :..:* . *::... * :.. *. :** * * .*.:**:***. : .: *.:.**:.***********:. *****: ************** * : .*. *:: :*:* *:* **** *** **.:**:**::*::* ** :* *:.* .:*******:*****:***. **** **:** :* :* :**.:**::* *** *::.:::: : :*. *::: . * *: :* :::*** : .. :*.*: :* ::.::.:* . .* : * * :.*.*** : *. .*:* .. : *:... :. .: * *. . *: * ::..* *.:*:**: . .** : :*:*.: *:*********.: ...**: *. * :***:****:*::*** * *** * ** . :** ****:*************** *.*****:****:* *.******** **********:********** :*** **. ", "identical_positions": 321, "similar_positions": 277, "identity": "30.54%" }, { "cls_id": "homologset.agr.RGD:1308756", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "B1WBU4-1", "uniprot_id": "ZBT8A_RAT", "id": "B1WBU4-1", "name": "Zinc finger and BTB domain-containing protein 8A", "aln": "MEISSHQSHLLEQLNEQRRQDVFCDCSILVEGKVFKAHRNVLFASSGYFKMLLSQNSKETSQPTTATFQTFSPDTFTVILDFVYSGKLSLTGQNVIEVMSAASFLQMTDVISVCKTFIKSSLDISEKEKDRYFSLSDKDTGSNGVERPSVYSSSWQEDGGSPRSHLSPDQGPAIVSGKPWNKYSYHPASQRSPQPPLAKHEQRKDPIKKTKHLRLPQPSEVVHFKSGKGDARTSDSGHHVSQSEEQVQVDAEVDPVSAGYPYSQGPEVASRSFPDNLPRLRFKCPYCTHVVKRKADLKRHLRCHTGERPYPCQACGKRFSRLDHLSSHFRTIHQACKLICRKCKRHVTDLTGQVVQEGTRRYRLCNECLTEVGMDSLPADLETEQHRVSPADGDKDCRWHLSEEENRSYVEIVEDGSADLVIQQVDDSEEEEEKEIKPNIR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CWH1-1", "uniprot_id": "ZBT8A_MOUSE", "id": "Q9CWH1-1", "name": "Zinc finger and BTB domain-containing protein 8A", "aln": "MEISSHQSYLLQQLNEQRRQDVFCDCSILVEGKVFKAHRNVLFASSGYFKMLLSQNSRETSQPTTATFQTFSPDTFTVILDFVYSGKLSLTGQNVIEVMSAASFLQMTDVISVCKTFIKSSLDISEKEKDRYFSLSDKDTGSNGVERPPFYSSSWQEEGGSPHSHVSPD------PGKPWNKYGYPPASQRSPQRPLAKHEQRKEPSKKAKHVRLPQPSEVVHFKPGKGEAQT-DSGNHVSQSEEQVPVDAEVDPAPAGFQYSQGPDGIARSFPDDLTRLRFKCPFCTHVVKRKADLKRHLRCHTGERPYPCQACGKRFSRLDHLSSHFRTIHQACKLICRKCKRHVTDLTGQVVQEGTRRYRLCNECLADVGMESLPADLEAEQHRTAPADGDKDCRWHLSEEENRSYVEIVEDGSADLVIQQVDDSEEEEEKEIKPNIR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96BR9-1", "uniprot_id": "ZBT8A_HUMAN", "id": "Q96BR9-1", "name": "Zinc finger and BTB domain-containing protein 8A", "aln": "MEISSHQSHLLQQLNEQRRQDVFCDCSILVEGKVFKAHRNVLFASSGYFKMLLSQNSKETSQPTTATFQAFSPDTFTVILDFVYSGKLSLTGQNVIEVMSAASFLQMTDVISVCKTFIKSSLDISEKEKDRYFSLSDKDANSNGVERSSFYSGGWQEGSSSPRSHLSPEQGTGIISGKSWNKYNYHPASQKNTQQPLAKHEPRKESIKKTKHLRLSQPSEVTHYKSSKREVRTSDSSSHVSQSEEQAQIDAEMDSTPVGYQYGQGSDVTSKSFPDDLPRMRFKCPYCTHVVKRKADLKRHLRCHTGERPYPCQACGKRFSRLDHLSSHFRTIHQACKLICRKCKRHVTDLTGQVVQEGTRRYRLCNECLAEFGIDSLPIDLEAEQHLMSPSDGDKDSRWHLSEDENRSYVEIVEDGSADLVIQQVDDSEEEEEKEIKPNIR", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "********:**:*********************************************:***********:*********************************************************************:.******...**..*** ..**:**:**: .**.****.* ****:..* ****** **:. **:**:**.*****.*:*..* :.:* **. ********. :***:*....*: *.**.: ::****:*.*:*****:***********************************************************************************::.*::*** ***:*** :*:*****.******:*************************************", "identical_positions": 358, "similar_positions": 62, "identity": "81.18%" }, { "cls_id": "homologset.agr.RGD:1308757", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "G3V6C2-1", "uniprot_id": "G3V6C2_RAT", "id": "G3V6C2-1", "name": "Homogentisate 1,2-dioxygenase", "aln": "MAELKYISGFGNECASEDPRCPGSLPKGQNNPQICPYNLYAEQLSGSAFTCPRNTNKRSWLYRILPSVSHKPFASID-QGHINHNWDEVGPDPNQLRWKPFEIPKACQKKVDFVSGLHTLCGAGDIRSNNGLAVHIFLCNSSMENRCFYNSDGDFLIVPQKGKLLIYTEFGKMFLQPNEICVIQRGMRFSVDVFEETRGYILEVYGVHFELPDLGPIGANGLANPRDFLIPVAWYEDRQVPGGFTVINKYQGKLFASKQDVSPFNVVAWHGNYTPYKYNLENFMVINAVAFDHADPSIFTVLTAKSLRPGVAIADFVIFPPRWGVADKTFRPPYYHRNCMSEFMGLIKGHYEAKQGGFLPGGGSLHSAMTPHGPDADCFEKASKAKLEPERIADGTMAFMFESSLSLAVTKWGLKTCGCLDEDYYKCWEPLQAHFTPTSRSPTEPK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O09173-1", "uniprot_id": "HGD_MOUSE", "id": "O09173-1", "name": "Homogentisate 1,2-dioxygenase", "aln": "MAELKYISGFGNECASEDPRCPGSLPKGQNNPQVCPYNLYAEQLSGSAFTCPRNTNKRSWLYRILPSVSHKPFESID-QGHVTHNWDEVGPDPNQLRWKPFEIPKASEKKVDFVSGLYTLCGAGDIKSNNGLAVHIFLCNSSMENRCFYNSDGDFLIVPQKGKLLIYTEFGKMSLQPNEICVIQRGMRFSVDVFEETRGYILEVYGVHFELPDLGPIGANGLANPRDFLIPVAWYEDRRVPGGYTVINKFQGKLFACKQDVSPFNVVAWHGNYTPYKYNLENFMVINAVAFDHADPSIFTVLTAKSLRPGVAIADFVIFPPRWGVADKTFRPPYYHRNCMSEFMGLIKGHYEAKQGGFLPGGGSLHSAMTPHGPDADCFEKASKAKLEPERIADGTMAFMFESSLSLAVTKWGLKTCSCLDENYYKCWEPLRSHFTPNSRSPTEPK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q93099-1", "uniprot_id": "HGD_HUMAN", "id": "Q93099-1", "name": "Homogentisate 1,2-dioxygenase", "aln": "MAELKYISGFGNECSSEDPRCPGSLPEGQNNPQVCPYNLYAEQLSGSAFTCPRSTNKRSWLYRILPSVSHKPFESID-EGQVTHNWDEVDPDPNQLRWKPFEIPKASQKKVDFVSGLHTLCGAGDIKSNNGLAIHIFLCNTSMENRCFYNSDGDFLIVPQKGNLLIYTEFGKMLVQPNEICVIQRGMRFSIDVFEETRGYILEVYGVHFELPDLGPIGANGLANPRDFLIPIAWYEDRQVPGGYTVINKYQGKLFAAKQDVSPFNVVAWHGNYTPYKYNLKNFMVINSVAFDHADPSIFTVLTAKSVRPGVAIADFVIFPPRWGVADKTFRPPYYHRNCMSEFMGLIRGHYEAKQGGFLPGGGSLHSTMTPHGPDADCFEKASKVKLAPERIADGTMAFMFESSLSLAVTKWGLKASRCLDENYHKCWEPLKSHFTPNSRNPAEPN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VKJ0-1", "uniprot_id": "HGD_DROME", "id": "Q9VKJ0-1", "name": "Homogentisate 1,2-dioxygenase", "aln": "MSEYKYLSGFGSHFSSEDERYPNSLPVGQNSPQVCPYKLYAEQLSGSAFTAPRTENMRTWLYRKLPSAAHLPFQPFKGAEYFSQNWDEQPPNPNQLRWKPFDLPPKDGKNVNFVEGLHTVCGAGDPRSRHGLAIHIYSCNGSMDNSAFYNSDGDFLIVPQQGVLDITTEFGRMSVAPNEICVIPQGIRFAVNVDSPSRGYILEVYDDHFVLPDLGPIGANGLANPRDFETPVAWFDDRDVKD-FQVISKFQGRLFVAKQNHTVFDVVAWHGNYVPFKYDLSKFMVINSVSFDHCDPSIFTVLTCPSLRAGTAIADFVIFPPRWSVQEHTFRPPYYHRNCMSEFMGLILGKYEAKEDGFAAGGATLHSMMTPHGPDVKCFEGASNAKLVPERVAEGTQAFMFESSLSLAVTKWGEETCQKLDAAYYECWQALKNNFQITKN------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:* **:****.. :*** * *.*** ***.**:***:************.**. * *:**** ***.:* ** .:. ..:**** *:*********::* *:*:**.**:*:***** :*.:***:**: ** **:* .*************:* * * ****:* : ******* :*:**:::* . :********. ** ****************** *:**::** * . : **.*:**:**..**: : *:********.*:**:*.:*****:*:***.*********. *:*.*.************.* ::******************* *:****:.** .**.:*** *******..*** **:.** ***:*:** **************** ::. ** *::**:.*: :* ... ", "identical_positions": 284, "similar_positions": 98, "identity": "63.68%" }, { "cls_id": "homologset.agr.RGD:1308758", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P0C673-1", "uniprot_id": "IGS11_MOUSE", "id": "P0C673-1", "name": "Immunoglobulin superfamily member 11", "aln": "MTRRRSAPASWLLVSLLGVATSLEVSESPGSVQVARGQTAVLPCAFSTSAALLNLNVIWMVIPLSNANQPEQVILYQGGQMFDGALRFHGRVGFTGTMPATNVSIFINNTQLSDTGTYQCLVNNLPDRGGRNIGVTGLTVLVPPSAPQCQIQGSQDLGSDVILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVASNAIGTSTCLLDLQVISPQPRSVGVIAGAVGTGAVLIVICLALISGAFFYWRSKNKEEEEEEIPNEIREDDLPPKCSSAKAFHTEISSSENNTLTSSNTYNSRYWNNNPKPHRNTESFNHFSDLRQSFS---GNAVIPSIYANGNHLVLGPHKTLVVTANRGSSPQVLPRNNGSVSRKPWPQHTHSYTVSQMTLERIGAVPVMVPAQSRAGSLV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5U2P2-1", "uniprot_id": "IGS11_RAT", "id": "Q5U2P2-1", "name": "Immunoglobulin superfamily member 11", "aln": "MTRRRSALASWLLLSLLGVAASLEVSESPGSVQVARGQTAVLPCAFSTSAALLNLNVIWMVIPLSNANQPEQVILYQGGQMFDGALRFHGRVGFTGTMPATNVSIFINNTQLSDTGTYQCLVNNLPDRGGRNIGVTGLTVLVPPSAPNCQIQGSQDIGSDVILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVASNAIGTSTCLLDLQVISPQPRSVGVIAGAVGTGAVLIVICLALTSGAFFYWRSKNKEEEEEEIPNEIREDDLPPKCSSAKAFHTEISSSENNTLTSSNTYNSRYWNNNPKPHKNTESFNHFSDLRQSFS---GNAVIPSIYANGNHLVLGPHKTLVVTANRGSSPQVMPRNNGSVSRKPWSQHTHSYTVSQMTLERIGAVPVMVPAQSRAGSLV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5DX21-1", "uniprot_id": "IGS11_HUMAN", "id": "Q5DX21-1", "name": "Immunoglobulin superfamily member 11", "aln": "MTSQRSPLAPLLLLSLHGVAASLEVSESPGSIQVARGQPAVLPCTFTTSAALINLNVIWMVTPLSNANQPEQVILYQGGQMFDGAPRFHGRVGFTGTMPATNVSIFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDVILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVASNAIGTSTCLLDLQVISPQPRNIGLIAGAIGTGAVIIIFCIALILGAFFYWRSKNKEEEEEEIPNEIREDDLPPKCSSAKAFHTEISSSDNNTLTSSNAYNSRYWSNNPKVHRNTESVSHFSDLGQSFSFHSGNANIPSIYANGTHLVPGQHKTLVVTANRGSSPQVMSRSNGSVSRKPRPPHTHSYTISHATLERIGAVPVMVPAQSRAGSLV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** :**. *. **:** ***:**********:******.*****:*:*****:******** *********************** ***************************************** *******************:********:*********************************************************************************.:*:****:*****:*::*:** ********************************************:********:******.**** *:****..***** **** *** ********.*** * ****************:.*.******** . ******:*: **********************", "identical_positions": 378, "similar_positions": 33, "identity": "87.7%" }, { "cls_id": "homologset.agr.RGD:1308759", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z8G8-1", "uniprot_id": "D3Z8G8_RAT", "id": "D3Z8G8-1", "name": "MAU2 chromatid cohesion factor homolog", "aln": "MAAQAAAAAQAAAAAQAAAAQAAQAEAAESWYLALLGFAEHFRTSSPPKIRLCVHCLQAVFPFKPPQRIEARTHLQLGSVLYHHTKNSEQARSHLEKAWLISQQIPQFEDVKFEAASLLSELYCQEN-SVDAAKPLLRKAIQISQQTPYWHCRLLFQLAQLHTLEKDLVSACDLLGVGAEYARVVGSEYTRALFLLSKGMLLLMERKLQEVHPLLTLCGQIVENWQGNPIQKESLRVFFLVLQVTHYLDAGQVKSVKPCLKQLQQCIQTIST---LHDDEILPSNPADLFHWLPKEHMCVLVYLVTVMHSMQAGYLEKAQKYTDKALMQLEKLKMLDCSPILSSFQVILLEHIIMCRLVTGHKATALQEISQVCQLCQQSPR--LFSNHAAQLHTLLGLYCVSVNCMDNAEAQFTTALRLTNHQELWAFIVTNLASVYIREGNRHQEVLYSLLERINPDHSFPVSSHCLRAAAFYVRGLFSFFQGRYNEAKRFLRETLKMSNAEDLNRLTACSLVLLGHIFYVLGNHRESNNMVVPAMQLASKIPDMSVQLWSSALLRDLNKACGNAMDAHEAAQMHQNFSQQLLQDHIEACSLPEHNLITWTDGPPPVQFQAQNG-----PNTSLASLL--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D2X5-1", "uniprot_id": "SCC4_MOUSE", "id": "Q9D2X5-1", "name": "MAU2 chromatid cohesion factor homolog", "aln": "MAAQAAAAAQAAAAAQAAAAQAAQAEAAESWYLALLGFAEHFRTSSPPKIRLCVHCLQAVFPFKPPQRIEARTHLQLGSVLYHHTKNSEQARSHLEKAWLISQQIPQFEDVKFEAASLLSELYCQEN-SVDAAKPLLRKAIQISQQTPYWHCRLLFQLAQLHTLEKDLVSACDLLGVGAEYARVVGSEYTRALFLLSKGMLLLMERKLQEVHPLLTLCGQIVENWQGNPIQKESLRVFFLVLQVTHYLDAGQVKSVKPCLKQLQQCIQTIST---LHDDEILPSNPADLFHWLPKEHMCVLVYLVTVMHSMQAGYLEKAQKYTDKALMQLEKLKMLDCSPILSSFQVILLEHIIMCRLVTGHKATALQEISQVCQLCQQSPR--LFSNHAAQLHTLLGLYCVSVNCMDNAEAQFTTALRLTNHQELWAFIVTNLASVYIREGNRHQEVLYSLLERINPDHSFPVSSHCLRAAAFYVRGLFSFFQGRYNEAKRFLRETLKMSNAEDLNRLTACSLVLLGHIFYVLGNHRESNNMVVPAMQLASKIPDMSVQLWSSALLRDLNKACGNAMDAHEAAQMHQNFSQQLLQDHIEACSLPEHNLITWTDGPPPVQFQAQNG-----PNTSLASLL--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y6X3-1", "uniprot_id": "SCC4_HUMAN", "id": "Q9Y6X3-1", "name": "MAU2 chromatid cohesion factor homolog", "aln": "------MAAQAAAAAQAAAAQAAQAEAADSWYLALLGFAEHFRTSSPPKIRLCVHCLQAVFPFKPPQRIEARTHLQLGSVLYHHTKNSEQARSHLEKAWLISQQIPQFEDVKFEAASLLSELYCQEN-SVDAAKPLLRKAIQISQQTPYWHCRLLFQLAQLHTLEKDLVSACDLLGVGAEYARVVGSEYTRALFLLSKGMLLLMERKLQEVHPLLTLCGQIVENWQGNPIQKESLRVFFLVLQVTHYLDAGQVKSVKPCLKQLQQCIQTIST---LHDDEILPSNPADLFHWLPKEHMCVLVYLVTVMHSMQAGYLEKAQKYTDKALMQLEKLKMLDCSPILSSFQVILLEHIIMCRLVTGHKATALQEISQVCQLCQQSPR--LFSNHAAQLHTLLGLYCVSVNCMDNAEAQFTTALRLTNHQELWAFIVTNLASVYIREGNRHQEVLYSLLERINPDHSFPVSSHCLRAAAFYVRGLFSFFQGRYNEAKRFLRETLKMSNAEDLNRLTACSLVLLGHIFYVLGNHRESNNMVVPAMQLASKIPDMSVQLWSSALLRDLNKACGNAMDAHEAAQMHQNFSQQLLQDHIEACSLPEHNLITWTDGPPPVQFQAQNG-----PNTSLASLL--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VFC0-1", "uniprot_id": "SCC4_DROME", "id": "Q9VFC0-1", "name": "MAU2 chromatid cohesion factor homolog", "aln": "---------------MSASTSTSTAASQDACYISLLGLAEYFRTSQPPNIKKCIQCLQALFTFMPPSKVEARTHLQMGQILMAYTKNIDLARQHLEKAWSISEPLPNFD-VKFDTASLLAQLHLQTDRNSHQAKAMLRRAVELSQNNVYWHCKLLLQLAQIHASDREYSLASELLAVGAESADEASATYLKVLFLLSRAMILMIERKTNDVLALLNSAGQIIDNNIPNPHQKEYLKVFFLVLQVCYYLALGQVKTVKPSLKQLQMSIQTIMAPNWPSDEAIFGANQLEMFVWLPKEQLYVLVYLVTVSHSMMAGYMDKAQKYTEKALTQIEKLKQQEDKPILSVFKVILLEHIVMCRMVMGNRELAIREIAAARDVCMAAPQRSLLRRHSAQLHCLIGLYSMSTNLFEHAERQFVVCVSETSERDLKLFANLNLAIIYLR--TKRDTDLKQILDAVSTENTHTYSSQALMGGFYYVQGLHAFHKNSFHEAKRFLRETLKMANAEDLNRLTSCSLVLLSHVFLSIGNSKESMNMVTPAMQLASKIPDIHVQLWGSAILKDLHRMSKDVQHEKDAYANHVKYSENLIADQRKCVQSAHHELVNWFQGDPPVTSGPPAAPVLLMPESSVTASVPVIASTSTAMQPAGQYGQFY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*::.:: * : :: *::***:**:****.**:*: *::****:*.* **.::*******:*.:* :*** : **.****** **: :*:*: ***::****::*: * : . . **.:**:*:::**:. ****:**:****:*: ::: *.:**.**** * ..: * :.*****:.*:*::*** ::* .**. .***::* ** *** *:******** :** ****:***.***** .**** : *: *: :* ::* *****:: ******** *** ***::******:*** *:**** : .**** *:*******:***:* *:: *::**: . ::* :*: *: .*:**** *:***.:*.* :::** **...: *..::* * *** :*:* .::: * .:*: :..:::.. **:.* .. :**:**.:*.:. ::************:*********:******.*:* :** :** ***.***********: ****.**:*:**:: . :. . ::* * ::*::*: *: :. . ..*:*:.* :* *** . . *::*::: : ", "identical_positions": 296, "similar_positions": 198, "identity": "45.54%" }, { "cls_id": "homologset.agr.RGD:1308760", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "F2Z3R5-1", "uniprot_id": "F2Z3R5_RAT", "id": "F2Z3R5-1", "name": "Protocadherin beta-1", "aln": "MAAARRKPLQNRQVGSLLLLWCVSVGGAATIRYSVAEEMESGSFVANVAKDLGLEVGKLAERGARLVAEGNRLHFRLHRKTGDLFVKEKLDREALCGKADPCVLHFEIILAEPLQSFRVEVRVFDINDNAPVFLNKEPLLKIPESTPLGSRFPLQSAQDLDVGLNGLQNYTLSANTYFHLHTRFRSHGPKYAELVLDNPLDREAQPEVNLTITAVDGGSPPKSGTANIRVVVLDVNDHVPQFSRLVYRAQVPENSDNGSLVVVVTATDLDEGTNKQITYSLAENPEAVLRTFLVDPQTGEVRLRGPLDFETIETYDIDIQATDGGGLSAHSKVLVEVVDVNDNPPEVTISSVSSPLAEDSPLQTVVALFTIRDRDVRVGGKITCFLKEDLPFVVKHTFRNSYSLVTDRILDREDVSNYNITLVAMDTGPPSLSTETVIEVVISDINDNSPVFQEDSYVLTVRENNSPAVFIGKVHAEDLDLGENAQVTYSLLPPKSGDLSVFAYISINSDNGKLYALRTMDYEAIQDFQFVVKATDGGFLSLSSQVTVRVVVLDDNDNRPMILYPLQNGTLPCNDLVPRSAEAGYLVTKVVAVDGDSGQNSWLSYHLLKATDLGLFSVQRQNGEIRTLRQISERDPMMQKLVILVQDHGQPALSTTASLNILLVDGFSEPYLQFQDPSKHSRKVNPTTKYLVISLAVLSFLFLFSVTVIIIIHLYQKIKHREKFTVQEHFYDDCNFPNNLVQGRGNGSLSQPCPYDMCSATGTGNSEFRFLKRFMPNFPFPHATGEVKTENDASLPPDSNRNRSRGSEGHARAGDDYM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y5F3-1", "uniprot_id": "PCDB1_HUMAN", "id": "Q9Y5F3-1", "name": "Protocadherin beta-1", "aln": "MAGTRRKSLQNRQVGSLLIFLCISVGDATTIRYSVAEEMESGSFVANVAKDLGLEVGKLAARGARLVSEGNKMHFRLHRKTGDLFVKEKLDRESLCGKADPCVLHFEVVLVEPLQSFRAEVRVFDINDNAPVFLNKEPLLKIPESTPLGSRFPLQSAQDLDVGLNGLQNYTLSANGYFHLHTRFCSHGPKYAELVLNKPLDREEQPEVNLTITAVDGGSPPKSGTAHIHVVVLDVNDHVPQFSRLVYRAQVSENSPNGSLVATVTAVDLDEGTNKAITYSLAQNPEAILKTFQIDPQNGEVRLRGPLDFEAIETYDIDIQATDGGGLSAHSKVLVEVVDVNDNPPEVMVSSVSSPLPEDSPPQTVVALFTIRDRDIRVGGKVTCFLREDLPFVIKPTFGNSYSLVTDRSLDREEVSGYNITIVAMDTGPPSLSAETMIEVLISDVNDNPPIFREDSYILTVRENNSPAVFIGKVHAEDLDLGENAQITYSLLPPKNGDLSVFAYISINSGNGKLYALRTMDYEAIQDFQFVVKATDGGFLSLSSQVTVRVVVLDDNDNRPMILYPLQNGTLPCNDLVPRSAEAGYLVTKVVAVDGDSGQNSWLSYHLLKATDLGLFSVQRQNGEIHTLRQISERDPMMQKLIILVQDHGQPALSTTVSLNILLVDGFSEPYLQFQDPTKHSRKVNPSTKYLVISLVILSFLFLLSVIVIFIIHVYQKIKYREKFTIQEHFYDDCNFSNNLVQGQGNGSLSRPCPYEMCSATGTGNSEFRFLKRFMPNFPFPHATGEIKMEAGSSLPPNSDRNKSQRLEGHDQVSDDYM", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.:***.**********:: *:***.*:******************************* ******:***::********************:*************::*.*******.******************************************************** ******** ***********::***** **********************:*:**********************.*** *****..***.******** ******:****:*:** :***.************:************************************ :*******.**** *************:*****:****:******:* ** ********* ****:**.****:***********:**:***:***:***.*:*:****:****************************:********.*************.*******************************************************************************************************************:***************:**************.********************:********:********.:******:** **:***:*****:*****:**********.******:******:****:******************************:* * .:****:*:**:*: *** :..****", "identical_positions": 723, "similar_positions": 76, "identity": "88.39%" }, { "cls_id": "homologset.agr.RGD:1308761", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q12824-1", "uniprot_id": "SNF5_HUMAN", "id": "Q12824-1", "name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------MMMMALSKTFGQKPVKFQLEDDGEFYMIG---SEVGNYLRMFRGSLYKRYPSLWRRLATVEERKKIVASSHGKKTKPNTKDHGYTTLATSVTLLKASEVEEILDG----NDEKYKAVSISTEPPTYLREQK---------------------AKRNSQWVPTLPNSSHHLDAVPCSTTINRNRMGRD---------------------------------------KKRTFPLCFDDHDPAVIHEN----------------------------------------ASQPEVLVPIRLDMEIDGQK--LRDAFTWNMNEKLMTPEMFSEILCDDLDLNPLT---FVPAIASAIRQQIESYPTDS-ILEDQS-----DQRVIIKLNIHVGNISLVDQFEWDMSEKENSPEKFALKLCSELGLGGEFVTTIAYSIRGQLSWHQKTYAFSEN-----------------PLPTVEIAIRNTGDADQWCPLLETLTDAEMEKKIRDQDRNTRRMRRLANTAPAW-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8J8YH81-1", "uniprot_id": "A0A8J8YH81_RAT", "id": "A0A8J8YH81-1", "name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------MMMMALSKTFGQKPVKFQLEDDGEFYMIG---SEVGNYLRMFRGSLYKRYPSLWRRLATVEERKKIVASSHGKKTKPNTKDHGYTTLATSVTLLKASEVEEILDG----NDEKYKAVSISTEPPTYLREQK---------------------AKRNSQWVPTLPNSSHHLDAVPCSTTINRNRMGRD---------------------------------------KKRTFPLCFDDHDPAVIHEN----------------------------------------ASQPEVLVPIRLDMEIDGQK--LRDAFTWNMNEKLMTPEMFSEILCDDLDLNPLT---FVPAIASAIRQQIESYPTDS-ILEDQS-----DQRVIIKLNIHVGNISLVDQFEWDMSEKENSPEKFALKLCSELGLGGEFVTTIAYSIRGQLSWHQKTYAFSEN-----------------PLPTVEIAIRNTGDADQWCPLLETLTDAEMEKKIRDQDRNTRRMRRLANTAPAW-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z0H3-1", "uniprot_id": "SNF5_MOUSE", "id": "Q9Z0H3-1", "name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------MMMMALSKTFGQKPVKFQLEDDGEFYMIG---SEVGNYLRMFRGSLYKRYPSLWRRLATVEERKKIVASSHGKKTKPNTKDHGYTTLATSVTLLKASEVEEILDG----NDEKYKAVSISTEPPTYLREQK---------------------AKRNSQWVPTLPNSSHHLDAVPCSTTINRNRMGRD---------------------------------------KKRTFPLCFDDHDPAVIHEN----------------------------------------ASQPEVLVPIRLDMEIDGQK--LRDAFTWNMNEKLMTPEMFSEILCDDLDLNPLT---FVPAIASAIRQQIESYPTDS-ILEDQS-----DQRVIIKLNIHVGNISLVDQFEWDMSEKENSPEKFALKLCSELGLGGEFVTTIAYSIRGQLSWHQKTYAFSEN-----------------PLPTVEIAIRNTGDADQWCPLLETLTDAEMEKKIRDQDRNTRRMRRLANTAPAW-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5U379-1", "uniprot_id": "SNF5_DANRE", "id": "Q5U379-1", "name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1-A", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------MALSKTYGQKPIKFQLEEDGDFYMIG---SEVGNYLRMFRGSLYKRYPSLSRRLATVEERKKIVASSH---------DHGYTTLATSVTLLKASEVEEIFDG----HDEKYKAVSISTEPPAYLREQK---------------------AKRNSQWVPTLPNSSHHLDAVPCSTTINRNRMGRD---------------------------------------KKRTFPLCFDDHDPAVIHEN----------------------------------------ASQQEVLVPIRLDMEIDGQK--LRDAFTWNMNEKLMTPEMFAEILCDDLDLSPLT---FVPAIASAIRQQIESYPTDS-ILDEQM-----DQRVIIKLNIHVGNISLVDQFEWDMSEKENSPEKFALKLCSELGLGGEFVTTIAYSIRGQLSWHQRTYAFSEN-----------------PLPTVEIAIRNTGDADQWCPLLETLTDAEMEKKIRDQDRNTRRMRRLANTAPAW-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24090-1", "uniprot_id": "Q24090_DROME", "id": "Q24090-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------MAL-QTYGDKPVAFQLEEGGEYYYVG---SEVGNYMRHFRGILYKKYPGMTRIVLSNEERKRLAESGLS-----------SHILASSVSLLRAVEVDDIMAG----NDEKYRAVSVNTSDTPVPRESK---------------------SKKQPQYVPTMPNSS-HLDAVPQATPINRNRVHTK---------------------------------------KVRTFPMCFDDTDPTASLEN----------------------------------------AAQKECLVPIRLDMELEGQK--LRDTFTWNKNESMITPEQFAEVLCDDLDLNPLP---FVPAIAQAIRQQIEAFPNDPPILEETC-----DQRVIVKLNIHVGNTSLVDQVEWDMSEKNNNPEEFAIKLCAELGLGGEFVTAIAYSIRGQLSWHCRTYAFSEA-----------------PLSTIDVPFRNPSDADAWAPFLETLTDAEMEKKIRDQDRNTRRMRRLANTTTGW-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P18480-1", "uniprot_id": "SNF5_YEAST", "id": "P18480-1", "name": "SWI/SNF chromatin-remodeling complex subunit SNF5", "aln": "MNNQPQGTNSVPNSIGNIFSNIGTPSFNMAQIPQQLYQSLTPQQLQMIQQRHQQLLRSRLQQQQQQQQQTSPPPQTHQSPPPPPQQSQPIANQSATSTPPPPPAPHNLHPQIGQVPLAPAPINLPPQIAQLPLATQQQVLNKLRQQAIAKNNPQVVNAITVAQQQVQRQIEQQKGQQTAQTQLEQQRQLLVQQQQQQQLRNQIQRQQQQQFRHHVQIQQQQQKQQQQQQQHQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQGQIPQSQQVPQVRSMSGQPPTNVQPTIGQLPQLPKLNLPKYQTIQYDPPETKLPYPTYWSDKKADTDTLLYEQIIQRDKINKYSLIRETNGYDPFSIYGFSNKEYISRLWHTLKYYQDLKNTRMKSITSTSQKIPSASIWGNGYSGYGNGITNTTTRVIPQVEVGNRKHYLEDKLKVYKQAMNETSEQLVPIRLEFDQDRDRFFLRDTLLWNKNDKLIKIEDFVDDMLRDYRFEDATREQHIDTICQSIQEQIQEFQGNPYIELNQDRLGGDDLRIRIKLDIVVGQNQLIDQFEWDISNSDNCPEEFAESMCQELELPGEFVTAIAHSIREQVHMYHKSLALLGYNFDGSAIEDDDIRSRMLPTITLDDVYRPAAESKIFTPNLLQISAAELERLDKDKDRDTRRKRRQGRSNRRGMLALSGTSASNTSMNGVHNTVAAGNASSLPPGEILLPDIADIPRTFRTPVPSTLMPGGVDVGPSVESYELRNTTTYKSRPDRPKPVSPPCYIIDHIPGHSLLLSIKLPGKVNTKEEFAAAPNDTSSGTNAMLPSPESLKTKLNSNIRAGVTIPSIPNPIANHTVTNSPNPTLQPVIPGGAASKSVPTPSLPIAPPVAPHDSEATLLTNSNNGSSNNNTQNT", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q06168-1", "uniprot_id": "SFH1_YEAST", "id": "Q06168-1", "name": "Chromatin structure-remodeling complex subunit SFH1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------MSHQNQLIPQAYISN--FHNRLTNEDDGIPIFTMAQQTRQHKRAK--VVNYAEYDNDLFDEFNMNGSNFNNADTHYKDNAVSHENTPALTNGVTMDGSEYNVLENMNGADSIISNNKYDAG---SNMVVESLSGLNSNNNASNGPSN-----------------KAQAQDIGNAVLPDLQDQHHNPFNILRYPKIRDTFINGK---------------------------------------VVSPYRLNTDQETKANANSG-------------------------------------------EAIMIPITLDIEHMGHT--IKDQFLWNYNDDSISPEEFASIYCKDLDMTSAT---LQTQIANIIKEQLKDLENIAATEIMSD------LHVIINLTCNLQDRFFEDNFQWNLNDKSLTPERFATSIVQDLGLTREFIPLISQSLHETILKIKKDWVDGHLIQDHVPN-----DAAFGYLSGIRLDIDELG--SNWCPRVEILTKEEIQKREIEKERNLRRLKRETDRLSRRGRRRLDDLETTMRM---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . . :: : : : . . : . ::. . . :. * .:. . . . . :. . : *. : . :. : . ::** *::: . ::* : ** *:. :. * * . * : . *.. *::*:: . :: ::* : : : *:.:*::.:.. **.** .: :* * **:. *: *:: : : . : . . : * : :: *::: :::*: ** :* ", "identical_positions": 34, "similar_positions": 104, "identity": "3.76%" }, { "cls_id": "homologset.agr.RGD:1308762", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q3UNH4-1", "uniprot_id": "GRIN1_MOUSE", "id": "Q3UNH4-1", "name": "G protein-regulated inducer of neurite outgrowth 1", "aln": "-----------------------------------------MRDCCSSP-KAIPAPPRHALDQSLGMDPRHTSSSGAAEGASCSERPAGSLACPS-----PNCSPLPETPRAHGALTSDNSGTTLFGKPEPMSSAEATPTASEIRNPVFSGKMDGNSLKQADSTSTRKEEAGSLRNEESMLKGKAEPMIYGKGEPGTVGRVDCTASGAENSGSLGKVDMPCSSKVDIVSPGGDNAGSLRKVETISSGKMD---PKTENVMHSRRERPGS----------------TGEGDLVSLRENDMKPPDNTDSASTKKTDPEFSGKLTPGSSGKTELVSSVTVAPVTSENVNPVCSGGAGPAAVGNSETLSSVKKDPQLLGKKEAVSSGEGGSVSVRMAETVSARQPEGMFPAKTDSTSSNSTGP--SGRADPVSLRNSELVSPVKPERLSSGQAERVSLVKTETLSSGKEDPRSSRRVDHTTVTGNMQTSQKGNPESSGKTD-LGSSSSGDTRSLGTWGSLSAAKAE-VTEGKGDPQPWKKA--------SLPASEKTDPLASSKAGSASQGKAETVSPGEVDAMTLGKTVPTSSGKTALVSPGKVDLMTSERAEGIPELQAS----EKGNPVNSTRVDTGATGSTEPKSGVKVITQIPG---ATSPGKVETPSLQKEQPQLSEKTDP--SRKVDPPTT--VEPVSLGKADSAS--PSPRKAESQTSAKTVPQAPDKAT--SSLRQSDGTPYSSAQPQRDTR-SIG-SLPEREPSASTS-----QKDLAAAAAQKSPSAEAAAPPPGPRTRDNFTKAPSWDAGAPPP-REDAGTQAGAQACVSVAVSPMSPQDGAGGPAFSFQAAPRAPSPAPRPPSRRDAGLQVSLGAAETRSVATGPMTPQAAAPPAVPPVFPEVRVRPGSVLAAALAPQEATEPVRDVSWDEKGMTWEVYGASMEVEVLGMAIQKHLERQIEEHGRQGAPAPAPPPAVRAGPGRAGSVRTAPAEGAAKRPPGLFRALLQSVRRPRCCSRAGPTAE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AJM0-1", "uniprot_id": "A0A8I6AJM0_RAT", "id": "A0A8I6AJM0-1", "name": "", "aln": "-----------------------------------------MRDRCSSP-KAIPAPPRHILDQSLGMDSRHSSSSGAGEGASCAEKPVGSLAC----------SPLPETVRAHGALTSEASETTLFGKPEPMSSVEA-PSAAEVRNPSSSEKMDSNSLKQEDSTSSRKEGAGSLRKEESMLVGKTEPLICGKGASETGVRVECSAPKKEESGSLGTVDTACSSKVDIVPPGGENAGSLRKVETIASGKMD---PRKENLMYSRREYPES----------------TGEGDLVSPRGNDMKPPD--------KADPGFSGELPPGSSGKTKHVSSVAVAPVTSENVNPASSGITDPVASGDTETLSSGKGDPRFLGKKEPVSTGESGPVSVRMAEPVSAGQPEGMVPAKKDPTSANSTGP--SGRVDSVSLRNSELVSPVKPEHLSSGQAERVSLVKTETLFSGKEDPRSSGRVE-TTVTGNIKTFQKGNPESSGKTDPVSSFSSGDAGSLGTLGSLSAAKTETVTEGKGDPQSLEKA--------SPTASEKADPLALCKESSASQGKAETVPSGEVGSTTLGKTASTSSGKTALVSPGKVDLTASERAEGVPELRAP----EKGNPGNSTRVDT-----TEPKSGVKVVTQLPG---ATSPGKVEAPSLQKEQPQPSEKTDP--SGKVDPTAS--VEPVSLGKADSASTSPSPRKAESQTSAKTVPQAPDKAT--SAFRQSDGTPYSSAQPRRDTR-SIG-ALPEPEPSASTS-----QKDLAAVAAQKSPSAEGAAPPPGPRTRDNFTKAPSWDAGAPPP-REDAGTQAGAQACVSVAVSPMSPQDGAVGPAFSFQAATRAPSPAPRPPSRRDAGLQVSLGAAETRSVATGPMTPQAAAPPAAPPVFPEVRVRPGSVLAAAMAPQEAAEPVRDVSWDEKGMTWEVYGASMEVEVLGMAIQKHLERQIEEHGRQG--APAPPPAVRAGPGRAGSVRTAPAEGAAKRPPGLFRALLQSVRRPRCCSRAGPTAE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7Z2K8-1", "uniprot_id": "GRIN1_HUMAN", "id": "Q7Z2K8-1", "name": "G protein-regulated inducer of neurite outgrowth 1", "aln": "MDTAEDPAWLQLLQKDSSPPGPRPTAFFCPQDGSLGAGSSAMRDYCPSQQKASPAPPRHTPDQSPGMESRHRSPSGAGEGASCSDGPRGSLACPSPTCFSPQESPSKETLEAHGASISGTPEATTSGKPEPVSSVKTEPKSSDDRNPMFLEKMDFKSSKQADSTSIGKEDPGSSRKADPMFTGKAEPEILGKGDPVAPGRMDPMTVRKEDLGSLGKVDPLCSSKTYTVSPRKEDPGSLRKVDPVSSDKVDPVFPRKEEPRYSGKEHPVSSEKVAPTSAEKVDLVLSGKRDPGPSGKADPMPLESMDSASTGKTEPGLLGKLIPGSSGKNGPVSSGTGAPGSLGRLDPTCLGMADPASVGNVETVPATKEDSRFLGKMDPASSGEGRPVSGHTDTTASA---------KTDLTSLKNVDPMSSGKVDPVSLGKMDPMCSGKPELLSPGQAERVSVGKAGTVSPGKEDPVSSRREDPISAGSRKTSSEKVNPESSGKTNPVSSGP-GDPRSLGTAGPPSAVKAEPATGGKGDPLSSEKAGLVASGKAAPTASGKAEPLAVGKEDPVSKGKADAGPSGQGDSVSIGKVVSTP-GKTVPVPSGKVDPVSLGKAEAIPEGKVGSLPLEKGSPVTTTKADPRASGKAQPQSGGKAETKLPGQEGAAAPGEAGAVCLKKETPQASEKVDPGSCRKAEPLASGKGEPVSLGKADSAP----SRKTESPSLGKVVPLSLEKTKPSSSSRQLDRKALGSARSPEGARGSEGRVEPKAEPVSSTEASSLGQKDLEAAGAERSPCPEAAAPPPGPRTRDNFTKAPSWEASAPPPPREDAGTQAGAQACVSVAVSPMSPQDGAGGSAFSFQAAPRAPS----PPSRRDAGLQVSLGAAETRSVATGPMTPQAAAP----PAFPEVRVRPGSALAAAVAPPEPAEPVRDVSWDEKGMTWEVYGAAMEVEVLGMAIQKHLERQIEEHGRQG--APAPPPAARAGPGRSGSVRTAPPDGAAKRPPGLFRALLQSVRRPRCCSRAGPTAE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *** *.* ** ****** *** **:.** *.***.*****:: * ***** ** ** .**** * . :* *****:**.:: *.::: *** *** :* ** **** ** .** *: :.*: **:** * *** . : *:: : *: ****.** ****. *.* ::.******:.::*.*:* *:.*: :* :* * * :*: * . * * : *::* : *:* ******. *** : ** : .::*.. * :.*.: *: **:.: * *.::*** :..*:**. .** : ..** *.* ** :...* **:.*.*** : : :.. *** **.*******: *: *: .***** ** * : :. .. : :* ********: :.* . **. **** *. **.*:* .* ***** . :** : .** *::*** * ...*:***:: ..*: .: ::**...*. ***. *..**** : :**.:** :. ***.* .:*:.*. ::*:** *. *::** *::**:. : .*:** ** ***.** . *.:* :: ***********. .**:** : .*.** : :*:. *: ** * .. .**:. ..:* * * *: ** :**. **** *..*::**..*.*******************:*.**** *************************** *.*******.**** ********************************* *.**********.****:** *.:********************:************************* *******.******:*******.:*******************************", "identical_positions": 515, "similar_positions": 218, "identity": "49.85%" }, { "cls_id": "homologset.agr.RGD:1308763", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZUD6-1", "uniprot_id": "A0A8I5ZUD6_RAT", "id": "A0A8I5ZUD6-1", "name": "", "aln": "MWPRDAEPEPDPESTHGPRSGRTVPGLRALLPARAFLCSLKGRLLLAESGLSFITFVCYVVSSASAFLTVPLLEFLLAIYFLFADAMQLNDKWQGLCWPMMDFLRCVTAALIYFVISITAVAKYSEGAYKAAGVFGFFATIVFAIDFYLIFNEVAKFLKQGDSGNETTAHRTEGECS-SDCLSAKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99LJ5-1", "uniprot_id": "CKLF3_MOUSE", "id": "Q99LJ5-1", "name": "CKLF-like MARVEL transmembrane domain-containing protein 3", "aln": "MWPPDAEPEPDPESAHGPRSGRTVPGLRALLPARAFLCSLKGRLLLAESGLSFITFICYVVSSASAFLTVPLLEFLLAVYFLFADAMQLNDKWQGLCWPMMDFLRCVTAALIYFVISITAVAKYSDGAYKAAGVFGFFATIVFAIDFYLIFNEVAKFLKQGDSGNETTAHRTEEENSNSDSDSD--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96MX0-1", "uniprot_id": "CKLF3_HUMAN", "id": "Q96MX0-1", "name": "CKLF-like MARVEL transmembrane domain-containing protein 3", "aln": "MWPPDPDPDPDPEPAGGSRPGPAVPGLRALLPARAFLCSLKGRLLLAESGLSFITFICYVASSASAFLTAPLLEFLLALYFLFADAMQLNDKWQGLCWPMMDFLRCVTAALIYFAISITAIAKYSDGASKAAGVFGFFATIVFATDFYLIFNDVAKFLKQGDSADETTAHKTEEENSDSDSD----", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** *.:*:****.: *.*.* :*********************************:***.********.********:***********************************.*****:****:** *************** *******:**********.:*****:** * * **. ", "identical_positions": 153, "similar_positions": 20, "identity": "82.26%" }, { "cls_id": "homologset.agr.RGD:1308764", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5M819-1", "uniprot_id": "SERB_RAT", "id": "Q5M819-1", "name": "Phosphoserine phosphatase", "aln": "------------------------------------MVSHSELRKLFCS-----------------------------------------ADAVCFDVDSTVIREEGIDELAKFCGVEAAVSEMTRRAMGGALPFKDALTERLALIQPSRDQVQRLLAEHPPHLTPGIRELVSRLQERNVQVFLISGGFRSIVEHVAAKLNIPTTNVFANRLKFYFNGEYAGFDETQPTAESGGKGKVIGFL-KEKFHFKKIIMIGDGATDMEACPPADAFIGFGGN--VIRQQVKDNAKWYITDFVELLGELEE------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99LS3-1", "uniprot_id": "SERB_MOUSE", "id": "Q99LS3-1", "name": "Phosphoserine phosphatase", "aln": "------------------------------------MVSHSELRKLFCS-----------------------------------------ADAVCFDVDSTVIREEGIDELAKFCGVEAAVSEMTRRAMGGALPFKDALTQRLALIQPSRDQVQRLLAEHPPHLTPGIRELVSRLQERNVQVFLISGGFRSIVEHVAAKLNIPTTNVFANRLKFYFNGEYAGFDEMQPTAESGGKGKVIRFL-KEKFHFKKIIMIGDGATDMEACPPADAFIGFGGN--VIRQQVKDNAKWYITDFVELLGELEE------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P78330-1", "uniprot_id": "SERB_HUMAN", "id": "P78330-1", "name": "Phosphoserine phosphatase", "aln": "------------------------------------MVSHSELRKLFYS-----------------------------------------ADAVCFDVDSTVIREEGIDELAKICGVEDAVSEMTRRAMGGAVPFKAALTERLALIQPSREQVQRLIAEQPPHLTPGIRELVSRLQERNVQVFLISGGFRSIVEHVASKLNIPATNVFANRLKFYFNGEYAGFDETQPTAESGGKGKVIKLL-KEKFHFKKIIMIGDGATDMEACPPADAFIGFGGN--VIRQQVKDNAKWYITDFVELLGELEE------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VSY6-1", "uniprot_id": "SERB_DROME", "id": "Q9VSY6-1", "name": "Phosphoserine phosphatase", "aln": "----------------------MSGSVLSLARPAAATNGHNLLTKQLNCNGNGTTGGAAKTTVASAITPPKQPQ--------LAAKVIQQSQIVCFDVDSTVICEEGIDELAEYCGKGSEVARVTKEAMGGAMTFQDALKIRLNIIRPTQQQVRDFIQERPSTLSKNVKRFVSHLKAEGKQVYLISGGFDCLIAPVANELGIPLKNVYANKMLFDYLGEYDSFDINQPTSRSGGKAEAIALIRKENSDDSLITMIGDGATDLEAVPPANYFIGFGGN--VVRPEVYRRAQYYVTDFEQLMGQ---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P42941-1", "uniprot_id": "SERB_YEAST", "id": "P42941-1", "name": "Phosphoserine phosphatase", "aln": "MSKFVITCIAHGENLPKETIDQIAKEITESSAKDVSINGTKKLSARATDIFIEVAGSIVQKDLKNKLTNVIDSHNDVDVIVSVDNEYRQAKKLFVFDMDSTLIYQEVIELIAAYAGVEEQVHEITERAMNNELDFKESLRERVKLLQGLQVDTLYDEIKQKLEVTKGVPELCKFLHKKNCKLAVLSGGFIQFAGFIKDQLGLDFC--KANLLEVDTDGKLTGKTLGPIVDGQCKSETLLQLCNDYNVPVEASCMVGDGGNDLPAMATAGFGIAWNAKPKVQKAAPCKLNTKSMTDILYILGYTDDEIYNRQ", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . * . . **:***:* :* *: :* .* * .:*..**.. : *: :* *: ::: : :. :: :: .: .: . *: .. :: ::**** : : :*.: ** : . *: . . . . : : . : . *:***..*: * ..*. *.:..: * : :**: ::* ", "identical_positions": 39, "similar_positions": 76, "identity": "12.54%" }, { "cls_id": "homologset.agr.RGD:1308766", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZQE9-1", "uniprot_id": "A0A8I5ZQE9_RAT", "id": "A0A8I5ZQE9-1", "name": "Interferon regulatory factor 9", "aln": "MATGKARCTRKLRNWIVEQVESGQFPGVCWDDAAKTMFRIPWKHAGKQDFREDQDAAIFKAWALFKEKHKDGDIGNPAVWKTRLRCALNKSSEFEEVPERGRMDVAEPYKVYRILPAGTLPTQPRNQKSPFKRSISSVSPERGECKENG----IVSHS---DSGSNVCGGGSNGGGSSDSCGSTSSS--ELEEGAGTTEATVQEDPVFMENPLPPNSDYSLLLTFIYGGRVVHEIQVHSLDCRLVAEPSDPE--------SSMVQQVVFPRPDP-----------LEPTQSLLNQLERGILVASNSRGLFVQRLCPIPISWNAPEAPPGPGPHLLPSNKCVELFSTTYFCRDLAQYFQGQGPLPKYQATLHFWDRSPSSSHTQENLITVRMEQAFARNLLEKIPEEEKAALFLVQHTEHQPATLAL--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61179-1", "uniprot_id": "IRF9_MOUSE", "id": "Q61179-1", "name": "Interferon regulatory factor 9", "aln": "MASGKVRCTRKLRSWIVEQVESGHFPGVCWDDAAKTMFRIPWKHAGKQDFREDQDAAIFKAWALFKEKHKDGDIGHPAVWKTRLRCALNKSSEFEEVPERGRMDVAEPYKVYRILPAGTLPNQPRNQKSPCKRSISCVSPEREENMENGRTNGVVNHS---DSGSNIGGGG-NGSNRSDSN-SNCNS--ELEEGAGTTEATIREDPVFLEHQLPLNSDYSLLLTFIYGGRVVGKTQVHSLDCRLVAERSDSE--------SSM-EQVEFPKPDP-----------LEPTQHLLNQLDRGVLVASNSRGLFVQRLCPIPISWNAPEAPPGPGPHLLPSNKCVELFKTTYFCRDLAQYFQGQGPPPKFQATLHFWEESPGSSHSQENLITVQMEQAFARHLLEKIPEEEKAALFLLQHTEQSPSALGH--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q00978-1", "uniprot_id": "IRF9_HUMAN", "id": "Q00978-1", "name": "Interferon regulatory factor 9", "aln": "MASGRARCTRKLRNWVVEQVESGQFPGVCWDDTAKTMFRIPWKHAGKQDFREDQDAAFFKAWAIFKGKYKEGDTGGPAVWKTRLRCALNKSSEFKEVPERGRMDVAEPYKVYQLLPPGIVSGQPGTQKVPSKRQHSSVSSERKE-EEDAMQNCTLSPSVLQDSLNNEEEGASGGAVHSDIGSSSSSSSPEPQEVTDTTEAPFQGDQRSLEFLLPPEPDYSLLLTFIYNGRVVGEAQVQSLDCRLVAEPSGSE--------SSM-EQVLFPKPGP-----------LEPTQRLLSQLERGILVASNPRGLFVQRLCPIPISWNAPQAPPGPGPHLLPSNECVELFRTAYFCRDLVRYFQGLGPPPKFQVTLNFWEESHGSSHTPQNLITVKMEQAFARYLLEQTPEQQAAILSLV--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B248-1", "uniprot_id": "A0A8M2B248_DANRE", "id": "A0A8M2B248-1", "name": "", "aln": "MASGRIRSTRRLRSWIVEQVNSGKYLGLVWDNPEKTMFRIPWKHAGKQDFRSEEDAAIFKAWAAFKGKLMENGNSDPASWKTRLRCALNKSPEFSEVTERSQLDISEPYKVYRLVPP----EEQGVVKVKKENGQKSVRNSKRKHSESENEQETEGKKIKEEIVAPQAINMSAQEIFINTGSAITIET-GMEKSDNNTEDIQLNFTIEAVPLVEKRALHTFHITVHYIGQEVLRQEVMRNDVRISYLPRSPVPPSLPSLSGSNFHRIFLPEPPSDISTDSSLAPRLNALKSLLPFMEWGVALTSLSGGIYAKRFCQGRVFWRGPHSSTTGPCKMERSGTPTQLFNREIFQQELECFRNG-GKQPQSEIILCFGEELLEGDNISDKHIIIKISLPWAEAQIEEVKAFRESIAILKSLASQSPTGEVTLNFVEVSE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:*: *.**:**.*:****:**:: *: **:. *****************.::***:***** ** * :.. . ** ************.**.**.**.::*::******:::*. : * :. ..* .: : *. . . : . : : . :: ..** : .. ::: :*. * *: * . :* * *: .. .* .:: :*.* . *:. : ** :: *: ::* . *::.:*:* : *..*.:.. :: *. .:** * ::* : :* * *: : * * :. ..: :: * :::. .:*. :*: . : * ", "identical_positions": 113, "similar_positions": 123, "identity": "26.04%" }, { "cls_id": "homologset.agr.RGD:1308767", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VHK9-1", "uniprot_id": "DHX36_MOUSE", "id": "Q8VHK9-1", "name": "ATP-dependent DNA/RNA helicase DHX36", "aln": "-------------------MSYDYHQSWSRDGGPR---GSG---QGSSGGGGGGSRGS-----------------------------GGGGGG----RGGRGRHPAHLKGREIGLWYAKKQTQ---------------------------------------------------------------------------KNKEAERQERAVVHMDERREEQIVQLLN---------------------------------------SVQAKTDKDSEAQIS-WFAPEDHGYGTEVSSEKKINSEKKLDNQEKKL----------------------------------------------------LNQEKKTFRITDKSYIDRDS-----EYLLQENEPNLSLDQHLL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EDLQRKKTDPRYIEMQRFRKKLPSYGMQKELVNLINNHQVTVISGETGCGKTTQVTQFILDNYIE-RGKGSACRIVCTQPRRISAISVAERVATERAESCGNGNSTGYQIRLQSRLPRKQGSILYCTTGIILQWLQSDSRLSSVSHIVLDEIHERNLQSDVLMTVIKDLLHFRSDLKVILMSATLNAEKFSEYFGNCPMIHIPGFTFPVVEYLLEDIIEKIRYVPDQKEHRSQFKRGFMQGHVNRQEKEEKEAIYKERWPAYIKELRTRYSASTVDVLQMMDDD-KVDLNLIAALIRYIVLEEEDGAILVFLPGWDNISTLHDLLMSQVMFKSD--KFLIIPLHSLMPTVNQT-------QVFKKTPPGVRKIVIATNIAETSITIDDVVYVIDGGKIKETHFDTQNNISTMSAEWVSKANAKQRKGRAGRVQPGHCYHLYNG-LRASLLDDYQLPEILRTPLEELCLQIKILRLGGIAYFLSRLMDPPSNEAVVLSIKHLMELSALDKQEE-LTPLGVHLARLPVEP-HIGKMILFGALFCCLDPVLTIAASLSFKDPFVIPLGKEKIADARRKELAKETRSDHLTVVNAFEGWEEAKRRGFRYEKDYCWEYFLSSNTLQMLHNMKGQFAEHLLGAGFVSSRSPKDPKANINSDNE--KIIKAVICAGLYPKVAKIRLNLGKKRKM-------------VKVHTKSD------------------------------------GLVSIHPKSVNVEQTDFH------------------YNWLIYHLKMRTSSIYLYDCTEVSPYCLLFFGGDISIQK--DKDQEIIAVDEWIVFQSPERIAHLVKGLRKELDSLLQEKIESPHPVDWDDTKSRDCAVLSAILDLIKTQEKATP---RNLPPRSQ--DGYYS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A2Z8-1", "uniprot_id": "DHX36_RAT", "id": "D4A2Z8-1", "name": "ATP-dependent DNA/RNA helicase DHX36", "aln": "-------------------MSYDYHQSWSRDGGPR---GSG---QGS-GGGGGGSRGS-----------------------------GGGGGG----RGGRGRHPAHLKGREIGLWYAKKQTQ---------------------------------------------------------------------------KNKEAERQERAVVHMDERREEQIVQLLN---------------------------------------SVQAKNDKDSEAQIS-WFAPEDHGYGTEVSSEKKINSEKKLDNQEKKL----------------------------------------------------LNQEKKTYRITDKSYIDRDS-----EYLLQQNEPNLGLDQQLL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EDLQKKKTDPRYIEMQRFRKKLPSYGMQKELVNLINNHQVTVISGETGCGKTTQVTQFILDNYIE-RGIGSACRIVCTQPRRISAISVAERVAAERAESCGNGNSTGYQIRLQSRLPRKQGSILYCTTGIILQWLQSDSRLSSVSHIVLDEIHERNLQSDVLMTVIKDLLHFRSDLKVILMSATLNAEKFSEYFGNCPMIHIPGFTFPVVEYLLEDIIEKIRYFPEQKEHRSQFKRGFMQGHVNRQEKEEKEAIYKERWPAYIKELQTRYSASTIDVLEMMDDD-KVDLNLIAALIRYIVLEEEDGAILVFLPGWDNISTLHDLLMSQVMFKSD--RFLIIPLHSLMPTVNQT-------QVFKKTPPGVRKIVIATNIAETSITIDDVVYVIDGGKIKETHFDTQNNISTMSAEWVSKANAKQRKGRAGRVQPGHCYHLYNG-LRASLLDDYQLPEILRTPLEELCLQIKILRLGGIAYFLSRLMDPPSDEAVVLSIKHLMELSALDKQEE-LTPLGVHLARLPVEP-HIGKMILFGALFCCLDPVLTIAASLSFKDPFVIPLGKEKIADARRKELAKETRSDHLTVVNAFEGWEEAKRRGFRYEKDYCWEYFLSSNTLQMLHNMKGQFAEHLLGAGFVSSRSPKDPKANINSDNE--KIIKAVICAGLYPKVAKIRLNLGKKRKM-------------VKVHTKSD------------------------------------GLVSIHPKSVNVEQTDFH------------------YNWLIYHLKMRTSSIYLYDCTEVSPYCLLFFGGDISIQK--DKDQEIIAVDEWIVFQSPERIAHLVKGLRKELDILLQEKIECPHPVDWNDTKSRDCAVLSAILDLIKTQEKAIP---RNLPPRSQ--DGYYS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H2U1-1", "uniprot_id": "DHX36_HUMAN", "id": "Q9H2U1-1", "name": "ATP-dependent DNA/RNA helicase DHX36", "aln": "-------------------MSYDYHQNWGRDGGPR---SSGGGYGGGPAGGHGGNRGS-----------------------------GGGGGGGGGGRGGRGRHPGHLKGREIGMWYAKKQGQ---------------------------------------------------------------------------KNKEAERQERAVVHMDERREEQIVQLLN---------------------------------------SVQAKNDKESEAQIS-WFAPEDHGYGTEVSTKNTPCSENKLDIQEKKL----------------------------------------------------INQEKKMFRIRNRSYIDRDS-----EYLLQENEPDGTLDQKLL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EDLQKKKNDLRYIEMQHFREKLPSYGMQKELVNLIDNHQVTVISGETGCGKTTQVTQFILDNYIE-RGKGSACRIVCTQPRRISAISVAERVAAERAESCGSGNSTGYQIRLQSRLPRKQGSILYCTTGIILQWLQSDPYLSSVSHIVLDEIHERNLQSDVLMTVVKDLLNFRSDLKVILMSATLNAEKFSEYFGNCPMIHIPGFTFPVVEYLLEDVIEKIRYVPEQKEHRSQFKRGFMQGHVNRQEKEEKEAIYKERWPDYVRELRRRYSASTVDVIEMMEDD-KVDLNLIVALIRYIVLEEEDGAILVFLPGWDNISTLHDLLMSQVMFKSD--KFLIIPLHSLMPTVNQT-------QVFKRTPPGVRKIVIATNIAETSITIDDVVYVIDGGKIKETHFDTQNNISTMSAEWVSKANAKQRKGRAGRVQPGHCYHLYNG-LRASLLDDYQLPEILRTPLEELCLQIKILRLGGIAYFLSRLMDPPSNEAVLLSIRHLMELNALDKQEE-LTPLGVHLARLPVEP-HIGKMILFGALFCCLDPVLTIAASLSFKDPFVIPLGKEKIADARRKELAKDTRSDHLTVVNAFEGWEEARRRGFRYEKDYCWEYFLSSNTLQMLHNMKGQFAEHLLGAGFVSSRNPKDPESNINSDNE--KIIKAVICAGLYPKVAKIRLNLGKKRKM-------------VKVYTKTD------------------------------------GLVAVHPKSVNVEQTDFH------------------YNWLIYHLKMRTSSIYLYDCTEVSPYCLLFFGGDISIQK--DNDQETIAVDEWIVFQSPARIAHLVKELRKELDILLQEKIESPHPVDWNDTKSRDCAVLSAIIDLIKTQEKATP---RNFPPRFQ--DGYYS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NHJ3-1", "uniprot_id": "A0A8M1NHJ3_DANRE", "id": "A0A8M1NHJ3-1", "name": "ATP-dependent DNA/RNA helicase DHX36", "aln": "-------------------MSLGYGNRHGRRGGGRKFGDVGSRWDAGASGVGDCTKSSE-----------------------WDSVFEHGLGG--CRRGGRGKHPSHLKGREIGLWYAKWGGI---------------------------------------------------------------------------KKSEAERRSRAVVHMDESREKHITQLLN---------------------------------------TVQRDLGRDVHPSTSQSWRNKDEARGHSYFDGDDPVETQNIMPLPKVE----------------------------------------------------PKDEKQEDAIKSRASLKEELNETNLEYLLQDVVQIPFLDEELK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KDQQKKEDNAAYIEMLKFRKKLPSYGMREELVRLISANRVLVISGETGCGKTTQVTQFILDDFIQ-RGQGSLCRVVCTQPRRISAISVAERVAVERAEPVGEGKSCGYQIRLQSRLPRKQGSLLYCTTGVILQWLHSDPYLSSITHLVLDEIHERSVQSDILITIVKDLLTARDDLKVVLMSATLNAEKFSKYFNNCPMIHIPGYTFPVTEYLLEDVVELLGFQPRYKQRKPHYRKRNNHGSSARPEKGKIEAKYHESWPCYARTLRDRFSDTTIEVLGMMDDDDNIDLELTAALIRHIAVNENEGAILVFLPGWDNISTLNDLLMSDQMFKSGRYRFIIIPLHSLMPTVSQTQVISLFPQVFKKPPPGVRKIVIATNIAETSITIDDVVYVIDGGKIKETHFDTQNNIRTMTAEWVSIANAKQRKGRAGRVSPGKCYHLYNG-LRASLLDNYQLPEIQRTPLEELCLQIKVLKLGPIATFLQKTMDPPSDRAIELAITHLVDLNALDRDEK-LTPLGFHLARMPVEP-HIGKMILFGALLGCLDPVLTIAASLSFKDPFFIPLGKEKIADQRRKMFSQNSRSDHLSIVNAFLGWEDAKRRGSRFEREYCWDNFLSANTLQMLQNMKGQFAEHLLRAGFVNSKDPKDPSSNINSENK--KLVKAVIVAGLYPKVAKISPSHNKKRPMP------------VKVYTKAD------------------------------------GKVCIHPKSVNAEETQFQ------------------YKWLVYHLKMKTTSIFLYDCTEVSPFSLLFFGGNISIQR--DQDQDTIAVDEWIVFQSPGRIAHLVKDLKKELDVLLEEKIKSPHPVDWKDQQSKDCAVISAIIDLITTQETPAGDPSKDSQPVYQRSDCLFE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q06698-1", "uniprot_id": "YL419_YEAST", "id": "Q06698-1", "name": "Putative ATP-dependent RNA helicase YLR419W", "aln": "MAKKTKNNSKSSTPVNDVPTTAGKKKAKGKKGQEPEPEDDKRAKQQSNRAKVTSTASWTGKLPHTILHETCQKRKWNKVEYDMKKIGDKGFIAIAVLSFTDPKTKETLTARMNDPTYDKASGKGLVIPQETPIEARHMASTIALYRIAYNTNLHMMLPPNHRKTWYALDDFRKDNLKTDEKRINKLFDLDPFKTMVEDRKLKAQREKEQVAQNNQAQKEQVARTILSSHGGISSSGKDRQERKVASHKNSHNPSLVRFPKKVWENSIFVDLDESSRQLIETSLKEKIDWQAKKISHKNETIAENREDLKAKLLTLQFRPKHVEEAMLYKDPLSFLLFNLPEDDLPPFFHKKKGDTKNKVEITNLPLSTRMIVERLTEIGVSSDEALLALQQNDMNENEAAGFLTREILPTLNSNTNEPVSETESIECWNQELESLESIYEGCVMDAKEDSHYTLNLIEKLKIKLKVYRTKNYPASLPGIVVSTFDKNYKLPDYIKKQILTRLLHYLQEGNLIGDMLVYHIYEWLKENISKIIDNPGPLIPDSDSKGAINKRNISNGKRSINNSSSRKFTKTTISEDTLSVLREEYTKRIKSSEYKSMQLVREQLPAWKKQKVIIDIINKNEVVLITGETGSGKSTQVVQFILDFLQKEKGDFGKTKIVCTQPRRISAIGLAERVSDERCVTCG--EEVGYVIRGVN-KTKASTRIKFMTTGVLVRLLQNARTMLENTIVVIDEVHERSIDTDLIVTLMKNLLHRVRGMKIVLMSATVNVDLFKKFFPGLATCHIEGRTFPITDYFLEDILSDLDFKIKRE-------KALSYDDDSVDERNNDDQYLKPRADSKFFTSGQINYDLLCQVVEYVHKR--------------LKAANDNGSIIVFLPGVGEINKCCNLLAN----KSNEADFMVLPLHSALTPEDQK-------RVFKK-YHGKRKVVVSTNIAETSITIDDCVATIDTGRAKSMFYNPKDNTTKLIESFISKAEVKQRRGRAGRVREGLSYKLFSKNLYENDMISMPIPEIKRIPLESLYLSVKAMGIKDVKAFLSTALDAPPLPALQKAERILTTIGLVDESDKSLTQLGQFISLMPVMDSKHGKLLIYGILFGCTDISVLLVSILGIGVLPFIG-GFENREKIKKLLCKYESRGDLFAVLEIVR--DYFKIKDSSIKRKYLRDNLLSYNKINEIKSSTAQYYSILKDVGFLPMDYKVGSISDLNRNERNFDILRAILTGAFYPHIARVQLPDVKYLSTSSGAVEKDPEAKMIKYWIRSEEYQDKLEEYKTKISQETQKVDLEDLPLPATRAFIHPSSVLFSTNSVNLEDAKLLSEVDGPISRQSKIPTVVKYPFVLFTTSQVTNKLYLRDLTPTTTLSLLLFGGAISYDIGGTIHSPGIVVDNWLPIRTWCKNGVLIKELRTQLDEAIRKKLESPDYAKKSQIDNSGADKTLKIVEKIIASEQ---------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : .: * . . . . . * . : *..* . * * :: :*:*... *.: :: :::::.: : :: . ... . . : . . . . :. * . . : . . . : : ::: * ..: :: :: . * .* .*::**:: :: :: :*. :.* :*:****.**:***.***** : :* . ::***********.:****: **. . * :. ** ** . .: . : : ***:::: *:. : . : :*:**:***.:::*:::*::*:** .:*::*****:*.: *.::* . . ** * ***:.:*:***::. : : : : . *: : : : :*: :.. : :::*:*:***** .:*.. :** . **. *:::**** :.. .*. :***: * **:*::************ * .** *: *. .::.::* .: .::* *:.***:****** * .*:*:. * . : . :*** * ***.* *.:* : : : **. :*.*. *: : * :. :*..:: ** ** .:: :** : **::::* *: * * : :.: *.: .* * *: . :: ::*.* ::::: . : : :. ::.* : :** *.:: ::. ..*: . * .**: .. :::* ::. .:::*:: ..:**::*:: * :* ::: . * . .:*** *::.: * :::: . *..::* * * .:. .**:*** ** : .. *.**:*: ::: : . *:* *:.:** :.:*::.*. .. .: .. .. *:: * :.* ", "identical_positions": 231, "similar_positions": 362, "identity": "15.45%" }, { "cls_id": "homologset.agr.RGD:1308768", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z0K7-1", "uniprot_id": "SLUR1_MOUSE", "id": "Q9Z0K7-1", "name": "Secreted Ly-6/uPAR-related protein 1", "aln": "MTLRWAMWLLLLAAWSMGYGEAFRCYTCEQPTAINSCKNIAQCKMEDTACKTVLETVEAAFPFNHSPMVTRSCSSSCLATDPDGIGVAHPVFCCFRDLCNSGFPGFVAGL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A7L8-1", "uniprot_id": "D4A7L8_RAT", "id": "D4A7L8-1", "name": "", "aln": "MTLRWAVWLLLLAAWSMGYGEAFRCYTCEQPTAINSCKNIVHCKLEDTACKTVLETVEAEFPFNHSPMVTRSCSSSCLATDPDGIGVAHPVFCCFRDLCNSGFPGLVTGL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P55000-1", "uniprot_id": "SLUR1_HUMAN", "id": "P55000-1", "name": "Secreted Ly-6/uPAR-related protein 1", "aln": "MASRWAVQLLLVAAWSMGCGEALKCYTCKEPMTSASCRTITRCKPEDTACMTTLVTVEAEYPFNQSPVVTRSCSSSCVATDPDSIGAAHLIFCCFRDLCNSEL-------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: ***: ***:****** ***::****::* : **:.*.:** ***** *.* **** :***:**:*********:*****.**.** :********** : ", "identical_positions": 70, "similar_positions": 21, "identity": "63.64%" }, { "cls_id": "homologset.agr.RGD:1308769", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M0X7-1", "uniprot_id": "A0ABK0M0X7_RAT", "id": "A0ABK0M0X7-1", "name": "DNA repair protein complementing XP-A cells homolog", "aln": "----------------MPVSPRSQAIPVVPCAWHIYGAELSVLQPLNKPAPSPTPAPSRTAPDPVFYMRRACFPAQSRLTP-----------AEPRTLELTRLGVTSIKAA-----------PKVIDTKGGFILEE----------EEEEKHKIGD-------------------VVHEPGPVMEFDYTICEECG-KEFMDSYLMNHFDLPTCDSCRDAD-DKHKLITKTEAKQEYLLKDCDLEKREPALRFIVKKNPRHSQWGDMKLYLKLQVVKRALEVWGSQEALEDAKEVRQENREKMKQKKFDKKVKELRRAVRSSVWK-----RET-TAHQHEYG-PEEH-LEEDMY---RKTCTLCGHELTYEKM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q64267-1", "uniprot_id": "XPA_MOUSE", "id": "Q64267-1", "name": "DNA repair protein complementing XP-A cells homolog", "aln": "----------------MATAEEKQTSP----------------EPVAADEPAQLPAAVRASVE--RKRQRALMLRQARLA------------ARPYPAAAATGGVASVKAA-----------PKMIDTKGGFILEE----------EEE-KHEIGN-------------------IVHEPGPVMEFDYTICEECG-KEFMDSYLMNHFDLPTCDSCRDAD-DKHKLITKTEAKQEYLLKDCDLEKREPALRFLVKKNPRHSQWGDMKLYLKLQVVKRALEVWGSQEALEDAKEVRQENREKMKQKKFDKKVKELRRAIRSSVWK-----RET-TTHQHKYG-PEEN-LEDDMY---RKTCTLCGHELTYEKM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23025-1", "uniprot_id": "XPA_HUMAN", "id": "P23025-1", "name": "DNA repair protein complementing XP-A cells", "aln": "----------------MAAADG--ALP----------------EAAALEQPAELPASVRASIE--RKRQRALMLRQARLAAR----------PYSATAAAATGGMANVKAA-----------PKIIDTGGGFILEE----------EEEEEQKIGK-------------------VVHQPGPVMEFDYVICEECG-KEFMDSYLMNHFDLPTCDNCRDAD-DKHKLITKTEAKQEYLLKDCDLEKREPPLKFIVKKNPHHSQWGDMKLYLKLQIVKRSLEVWGSQEALEEAKEVRQENREKMKQKKFDKKVKELRRAVRSSVWK-----RET-IVHQHEYG-PEEN-LEDDMY---RKTCTMCGHELTYEKM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P28518-1", "uniprot_id": "XPA_DROME", "id": "P28518-1", "name": "DNA repair protein complementing XP-A cells homolog", "aln": "---------------MSAEVSTNESAP-------------------PAEKKSKLTNAQKARIE--RNQAKAQKLREAKLVSHPFKELASNKEGGTHPEAALSQGSSVIKVQG----------TKYIDSGGGFLLEQPVMPTG---VGPAGLNKSGEEAP----------------PILDDAIAIPVQYEECLECG-DMFADSYLFNNFGHSVCDKCRDKD-ERYALITRTEAKAEYLLKDCDFDKREPKLRYISRKNPHNVRWGEMKLYLHLQIHQRALEVWGSEEELVRQHEAREDKREEGKARKYNKKMKQLRMEVRSSIYT-----KKTHEVHEHEFG-PDTYDEEEDTY---THTCITCPYSETYEKM", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P28519-1", "uniprot_id": "RAD14_YEAST", "id": "P28519-1", "name": "DNA repair protein RAD14", "aln": "MTPEQKAKLEANRKLAIERLRKRGILSSDQLNRIESRNEPLKTRPLAVTSGSNRDDNAAAAVHVPNHNGQPSALANTNTNTTSLYGSGVVDGSKRDASVLDKRPTDRIRPSIRKQDYIEYDFATMQNLNGGYINPKDKLPNSDFTDDQEFESEFGSKKQKTLQDWKKEQLERKMLYENAPPPEHISKAPKCIECHINIEMDPVLHDVFKLQVCKQCSKEHPEKYALLTKTECKEDYFLTDPELND-EDLFHRLEKPNPHSGTFARMQLFVRCEVEAFAFKKWGGEEGLDEEWQRREEGKAHRREKKYEKKIKEMRLKTRAQEYTNRLREKKHGKAHIHHFSDPVDGGIDEDGYQIQRRRCTDCGLETEEIDI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : . :. ::. . :: .. : **:: : : *. . * ** . *. * : * .*..* . . ::: *:*:**.* :*:*.* :::. * :: : : **: :. *:*::: :: ::: **.:* * : *:: : . : :*::**:*::* *:. :. :: .* *.:. * ::* * : * * . .:", "identical_positions": 42, "similar_positions": 88, "identity": "11.29%" }, { "cls_id": "homologset.agr.RGD:1308770", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q4QR80-1", "uniprot_id": "RT25_RAT", "id": "Q4QR80-1", "name": "Small ribosomal subunit protein mS25", "aln": "MP-MKGRFPIRRTLQYLGSGDVVFKESVKVMTVNYNTHGELGEGARKFVFFNIPQIQYKNPWVQIMLFKNMTPSPFLRFYLESGEQVLVDVETKSNTEIVEHIKKILGKKEETLREEELEKQQRFHPGNFGPRKYCLRECMCEVEGQVPCPGLVPLPKEMTGKYKAALKANT--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D125-1", "uniprot_id": "RT25_MOUSE", "id": "Q9D125-1", "name": "Small ribosomal subunit protein mS25", "aln": "MP-MKGRFPIRRTLQYLGRGDVVFKESVKIMTVNYNTYGELGEGARKFVFFNIPQIQYKNPWVQIMMFKNMTPSPFLRFYLDSGEQVLVDVETKSNKEIMEHIKKILGKKEETLREEELEKQQRFHPGNFGPRKYCLRECMCEVEGQVPCPGLVPLPKEMTGKYKAALKAST--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P82663-1", "uniprot_id": "RT25_HUMAN", "id": "P82663-1", "name": "Small ribosomal subunit protein mS25", "aln": "MP-MKGRFPIRRTLQYLSQGNVVFKDSVKVMTVNYNTHGELGEGARKFVFFNIPQIQYKNPWVQIMMFKNMTPSPFLRFYLDSGEQVLVDVETKSNKEIMEHIRKILGKNEETLREEEEEKKQLSHPANFGPRKYCLRECICEVEGQVPCPSLVPLPKEMRGKYKAALKADAQD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VY28-1", "uniprot_id": "RT25_DROME", "id": "Q9VY28-1", "name": "Small ribosomal subunit protein mS25", "aln": "MPFMKGREPIRRTLKYLNAGKLVLKDKVRIFSVNYNTYGAHHAGARDFVFWNIPQIQFKNPEVQVLTLKNMTPSPFVRCYFDDGRDMLIDLDSRNRNDIIDHLVKVVGKTREQLDAEERLKESKDNPANFGYG--CGRHCICEIPGQVPCPGTVPLPDHMRGKILFAPK-----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** **** ******:**. *.:*:*:.*::::*****:* ***.***:******:*** **:: :********:* *::.*.::*:*::::...:*::*: *::**..* * ** *:. :*.*** * *.*:**: ******. ****..* ** * * ", "identical_positions": 88, "similar_positions": 51, "identity": "50.57%" }, { "cls_id": "homologset.agr.RGD:1308772", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K3W1-1", "uniprot_id": "A0A0G2K3W1_RAT", "id": "A0A0G2K3W1-1", "name": "von Willebrand factor A domain-containing protein 8", "aln": "MQSRLLLLGVPGGLGDVASRRVRLLLRQVLRGRPGGGQQRLEVRLMHAG-VTDSGETVNIGDVSYKLKTPKNPELVPQNYIAAS-----------------------PSQSVVQHLRWIMQKDLLGQDVFLIGPPGPLRRSVAMQYLELTKQEVEYIALSRDTTETDLKQRREIRAGTAFYIDQCAVRAATEGRTLVLEGLEKAERNVLPVLNNLLENREMQLEDGRFLMSAERYDKLLRDHTKEELDAWKIVRVSENFRVIALGLPVPRYSGNPLDPPLRSRFQARDIYFLPFQDQLKLLYSVGANVSAEKISQLLSFATTLCSQESSTLGLPDFPLDSLPEAVQILDSFPMMPIEHAIRWMYPYTVLLGHEGKMAVEGVLKRFELQGSGHSLLPKEIVRVERMTDSHISHAHVTIRVSGKEVTIKVPAGTRAVNQPCAPDRFIQTVSHKQLLAEMMQSHMVKDICLIGGKGCGKTVMAKNFAALLGYSIEPIMLYQDMTARDLLQQRYTLPNGDTAWRSSPLVSAAREGKLVLLDGIHRVNAGTLAVLQRLIHDRELSLYDGSRLLREDRYLCLKERLQLTDEQLQNRSIFPIHPSFRIIALAEPPVVGSTTQQWLGPEFLTMFFFHHMKPLVKSEELQVIKEMVPNVPQEALEKLLSVTHKLRETQDPTAQSLAASLSTRQLLRISRRLSQYPSE---NLHDAITKACLSRFLPSLAQSALEKNLADAAIEINADSSLEPELENYKCEVVAGSLKIGTVSAPVHNAHEK--MKVPDVLFYDNVQHMVVMEDMLKDFVLGEHLLLVGNQGVGKNKIVDRFLHLLNRPREYIQLHRDTTVQSLTLQPSVKDGLIVYEDSPLVKAVKLGHILVVDEADKAPTNVTCILKTLVENGEMILADGRRIVADAASVDGRENAIVVHPDFRMVVLANRPGFPFLGNDFFGTLGDIFSCHAIDNPKPHSELEMLKQYGPNVPVPVLEKLVAAFGELRNLADQGIINYPYSTREVVNIVKHLEKFPTEGLSSVVRNVFDFDSYNNDMREILMNTLHKYGIPIGAKPTNVQLAKEFPLPEKTFMGYWIIGQTGNGMQKVLCPAETHRIDIKGPVLVNIEKYPIEKHESRFLNFTEECTSWRFPVDEVNLISDIAVSHENGEHTLYVATCNPISLYFMNMTGENGFFVDFFDIFPRMASGSWRPFVTVAPLGSPLRGQVVLHEEQSNVVLLLDTTGRAIHRLVLPTE---ESTSKKSSWWNKEEGE-TYRMCKEFSHKNWVVFYRQTGNSLTVLDVLEGLTHTISLPINLRTVFLVAEDKWLLVENKTNQKCLLTKPAHIGAEDTGACQLYMLKEELPSTGFGVTQETEFYVPHKVSSDQLSSENLTSAVGQKIASPNRILSDEKSHATIVVGFPDLMSPCEVYSWKRSSSLGKPSVTNITMYTGKRTSVTPRHNNCVTLTHTNQVVRILPAGEVPLKDIYPKDVTPPQTAGYIEVTDLQAKKLRYIPVPSAESLSPYTAWLSAISDTDALLAEWDKSSVVTVDMGGCVRLWETGLERLQQSLMEWRNMIGQDSDKHMQITIERDSNEDVSEPKHGKEDPDNMPHVGGNTWAGGTGGRDTAGLGGKGGPYRLDAGHPVYQVSEVEKDAVPEDIKRAAREMAQRAFQQRLKEIQMSEYDAATYERFSRAVQRQVHALRVILDNLQAKGKERQWLRHQATGELDDAKIIDGLAGEKAIYKRRGDLEPQLGSPQQKPKRLRLVVDVSGSMYRFNGVDRRLERSMEAVCMVMEAFENYEEKFKYDIAGHSGDGYNIKLVPVNKIPKNNKQRLEILKTMHAHSQFCMSGDHTLEGTEHAIKDI-TTEEADEYFVIILSDANLSRYGINPARFAQILTS-NPQVNAFAIFIGSLGDQAARLQRTLPAGRSFIAMDTKKIPQILQQIFTSTMLSSI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CC88-1", "uniprot_id": "VWA8_MOUSE", "id": "Q8CC88-1", "name": "von Willebrand factor A domain-containing protein 8", "aln": "MQSRLLLLGAPGGLGDVASRRVRLLLRQVLRGRPGGDQQRLEVRLLHSG-ATDSGETVSIGDVSYKLKTPKNPELVPQNYISDS-----------------------PAQSIVQHLRWLMQKDLLGQDVFLIGPPGPLRRSVAMQYLELTKREVEYIALSRDTTETDLKQRREIRAGTAFYIDQCAVRAATEGRTLVLEGLEKAERNVLPVLNNLLENREMQLEDGRFLMSAERYDKLLQDHTKEELDAWKIVRVSENFRVIALGLPVPRYSGNPLDPPLRSRFQARDIYFLPFQDQLKLLYSVGANVSAEKISQLLSFATTLCSQESSTLGLPDFPLDSLPEAVQILDSFPMMSIEHALQWVYPYTLLLGHEGKMAVEGVLKRFELQGSGHSLLPKEIVRVERMTDSHGSYAHVTIRVAGKEVTIKVPAGTRAVNQPCAPDHFIQTVSHKQLLAEMVQSHMVKDICLIGGKGCGKTVIAKNFAALLGYSIEPIMLYQDMTARDLLQQRYTLPNGDTAWRSSPLVSAAREGKLVLLDGIHRVNAGTLAVLQRLIHDRELSLYDGSRLLREDRYLSLKEKLQLTDEQLQNRSIFPIHPSFRIIALAEPPIVGSTTQQWLGPEFLTMFFFHHMKPLVKSEEIQVIKETVPNVPQEALEKLLSVTHKLRETQDPTAQSLAASLSTRQLLRISRRLSKYPSE---NLHDAITKACLSRFLPSLAQSALEKNLADAAIETNTEDSLEPELENYKCEVVAGSLKIGAVSVPVHNAHEK--MKVPDVLFYDNVQHMVVMEDMLKDFVLGEHLLLVGNQGVGKNKIVDRFLHLLNRPREYIQLHRDTTVQSLTLQPTVKGGLIVYEDSPLVKAVKLGHILVVDEADKAPTNVTCILKTLVENGEMILADGRRIVADAANVDGRENLVAIHPDFRMLALANRPGFPFLGNDFFGTLGDIFSCHAIDNPKPHSELSMLKQYGPDVPEPVLQKLVAAFGELRNLADQGIINYPYSTREVVNIVKHLQKFPTEGLSSVVRNVFDFDSYNNDMREILMNTLHKYGIPIGAKPTNVQLAKEFPLPEKTFMGYWIVGQTGNGMQKVLCPAETNHVDIKGPVLVNMEKYPIEKHEARFLSFTEECTSWKFPLDEVNLICDIAVSHENGEQTLYVAACNPVSLYFMNMTGKNGFFVDFFDIFPRMASGSWRPFVTVAPLGSPLRGQVVLHEEQSNAVLLLDTTGSAIRRLVLPTE---EFTSKKSSWWSKEEGE-TYRMCKEFSHKNWVVFYKQTGNSLTVLDVLEGLAHTISLPINLRTVFLVAEDKWLLVENETNQKYLLTKPAHIGSEDTGACQLYMLKEELPSTGFGVTQETEFCIPDKVSSDQLSSENLTSAVGQKIASPNRILSDENSHATIVVGFPDLMSPSEVYSWKRSSSLRQPSVTSMTMYTGKRTNATPRHNNCVTLTHTNQVVRILPPGEVPLKDLYPKDVTPPQTAGYIEVTDLQAKKLRYIPVPSAESLSPYTAWISAISDTDALLAEWDKSSVVTVDMGGRVRLWETGLERLQQSLMEWRNMIGQDSDKHVQITIERDSNEDVSDPKHGKEDPDNMPHVGGNTWAGGTGGRDTAGLGGKGGPYRLDAGHPVYQVSEVEKDAVPEDVKRAAREMAQKAFQQRLKEIQMSEYDAATYERFSSAVQRQVHALRIILDNLQAKGKERQWLRHQATGELDDAKIIDGLAGEKSIYKRRGDLEPQLGSPQQKPKRLRLVVDVSGSMYRFNGVDRRLERSMEAVCMVMEAFENYEEKFKYDIAGHSGDGYNIKLVPVNQIPKNNKQRLEILKTMHEHSQFCMSGDHTLEGTEHAIKDI-TTEEADEYFVIILSDANLSRYGINPARFAQILTS-DPQVNAFAIFIGSLGDQAARLQRTLPAGRSFIAMDTKKIPQILQQIFTSTMLSSI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A3KMH1-1", "uniprot_id": "VWA8_HUMAN", "id": "A3KMH1-1", "name": "von Willebrand factor A domain-containing protein 8", "aln": "MQSRLLLLGAPGGHGGPASRRMRLLLRQVVQRRPGGDRQRPEVRLLHAGSGADTGDTVNIGDVSYKLKIPKNPELVPQNYISDS-----------------------LAQSVVQHLRWIMQKDLLGQDVFLIGPPGPLRRSIAMQYLELTKREVEYIALSRDTTETDLKQRREIRAGTAFYIDQCAVRAATEGRTLILEGLEKAERNVLPVLNNLLENREMQLEDGRFLMSAERYDKLLRDHTKKELDSWKIVRVSENFRVIALGLPVPRYSGNPLDPPLRSRFQARDIYYLPFKDQLKLLYSIGANVSAEKVSQLLSFATTLCSQESSTLGLPDFPLDSLAAAVQILDSFPMMPIKHAIQWLYPYSILLGHEGKMAVEGVLKRFELQDSGSSLLPKEIVKVEKMMENHVSQASVTIRIADKEVTIKVPAGTRLLSQPCASDRFIQTLSHKQLQAEMMQSHMVKDICLIGGKGCGKTVIAKNFADTLGYNIEPIMLYQDMTARDLLQQRYTLPNGDTAWRSSPLVNAALEGKLVLLDGIHRVNAGTLAVLQRLIHDRELSLYDGSRLLREDRYMRLKEELQLSDEQLQKRSIFPIHPSFRIIALAEPPVIGSTAHQWLGPEFLTMFFFHYMKPLVKSEEIQVIKEKVPNVPQEALDKLLSFTHKLRETQDPTAQSLAASLSTRQLLRISRRLSQYPNE---NLHSAVTKACLSRFLPSLARSALEKNLADATIEINTDDNLEPELKDYKCEVTSGTLRIGAVSAPIYNAHEK--MKVPDVLFYDNIQHVIVMEDMLKDFLLGEHLLLVGNQGVGKNKIVDRFLHLLNRPREYIQLHRDTTVQTLTLQPSVKDGLIVYEDSPLVKAVKLGHILVVDEADKAPTNVTCILKTLVENGEMILADGRRIVANSANVNGRENVVVIHPDFRMIVLANRPGFPFLGNDFFGTLGDIFSCHAVDNPKPHSELEMLRQYGPNVPEPILQKLVAAFGELRSLADQGIINYPYSTREVVNIVKHLQKFPTEGLSSVVRNVFDFDSYNNDMREILINTLHKYGIPIGAKPTSVQLAKELTLPEQTFMGYWTIGQARSGMQKLLCPVETHHIDIKGPALINIQEYPIERHEERSLNFTEECASWRIPLDEINIICDIATSHENEQNTLYVVTCNPASLYFMNMTGKSGFFVDFFDIFPRTANGVWHPFVTVAPLGSPLKGQVVLHEQQSNVILLLDTTGRALHRLILPSE---KFTSKKPFWWNKEEAE-TYKMCKEFSHKNWLVFYKEKGNSLTVLDVLEGRTHTISLPINLKTVFLVAEDKWLLVESKTNQKYLLTKPAHIESEGSGVCQLYVLKEEPPSTGFGVTQETEFSIPHKISSDQLSSEHLSSAVEQKIASPNRILSDEKNYATIVVGFPDLMSPSEVYSWKRPSSLHKRSGTDTSFYRGKKKRGTPKQSNCVTLLDTNQVVRILPPGEVPLKDIYPKDVTPPQTSGYIEVTDLQSKKLRYIPIPRSESLSPYTTWLSTISDTDALLAEWDKSGVVTVDMGGHIRLWETGLERLQRSLMEWRNMIGQD-DRNMQITINRDSGEDVSSPKHGKEDPDNMPHVGGNTWAGGTGGRDTAGLGGKGGPYRLDAGHTVYQVSQAEKDAVPEEVKRAAREMGQRAFQQRLKEIQMSEYDAATYERFSGAVRRQVHSLRIILDNLQAKGKERQWLRHQATGELDDAKIIDGLTGEKAIYKRRGELEPQLGSPQQKPKRLRLVVDVSGSMYRFNRMDGRLERTMEAVCMVMEAFENYEEKFQYDIVGHSGDGYNIGLVPMNKIPKDNKQRLEILKTMHAHSQFCMSGDHTLEGTEHAIKEI-VKEEADEYFVIVLSDANLSRYGIHPAKFAQILTR-DPQVNAFAIFIGSLGDQATRLQRTLPAGRSFVAMDTKDIPQILQQIFTSTMLSSV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0R0T1-1", "uniprot_id": "VWA8_DANRE", "id": "B0R0T1-1", "name": "von Willebrand factor A domain-containing protein 8", "aln": "MHSRILFKGTA---AAVAARRIRHILGPLMS-KEGWNCSAHEVKLLNTS----SGDTVKIGEISYVLKTPKNPELVPVNHMMEA-----------------------LPQMVTQHLRWIMQKDLLGQDVFLIGPPGPLRRSIAMQYLELTKREVEYVALSRDTTETDLKQRREIRSGTAFYIDQCAVRAATEGRILVLEGLEKAERNVLPVLNNLLENREMQLEDGRFLMSAHRYDKLLEEHTKEELDAWKIVRVSEDFRVIALGLPVPRYKGNPLDPPLRSRFQARDIYYLPFKDQLEHLYRIGANVSAERVSQLLSFATTLCSQESASLSLPDFPVDNLPSALTVLNLFPMLSVQQLVQRLYPYEAMLGKEGRTAVEGVLNRFELTDGSTKPSPTAVVNIEPVNGGQAEQAAVTLNITNQKITFQVPSGTRPIRPPNSSPTFINTPTHERLLAEMMQSHLVKDICLIGAKGCGKSVIAREFAEMLGYSIEPVMLYQDMTARDLLQQRYTLPNGDTAWRASPLVTAAQEGKLVLLDGIHRVNLGTLAVLSRLLHDRELDLYDGTRLLRFDRYQALKEELQLTDQQLQDRSIFPIHPSFRIIALAEPPVIGSTTQQWLNPEILTMFLFHTIKPLAKAEETAVLQGMIPNVPGEAVEQLQHLTHSLRKSNDPTALSLASSLSTRQLLRICRRLSQYPQE---SVAHAVHKACLSRFLPSLARSSLEKSLANCSIEDHPDPASE-QKQLYTCTVKDGLLTIGNVSAPVYSPDEK--MKVPDVLFYENVQHMMVMQDMLKDFLLGEHLLLVGNQGVGKNKIVDRFLHLMNRPREYLQLHRDTTVQTLTLQPSVRDGIIIYEDSPLVKAVKMGHILVIDEADKAPTNVTCILKALVESGEMILADGRRIVSDALEAAGRPNAIPMHPDFRMIVLANRPGFPFLGNDFFGALGDIFSCHAVDNPKPQAEFAMLKQYGPDVPDAVLQKLVAAFGELRAMADQGTITYPYSTREVVNIVKHLQKFPDEGLANVVRNVFDFDSYNKDMREVLISALHKHGIPIGAKPTSVHLAKELPLPDCKMTGYWTISQGGNTRRKLLCPTETHRIDIKGPVFLRVQSYPSKRHESRSLSFTEEQAHWQIPMNEVNIVCDVTTAKDS----IYVATCNPVSLYAMKEKGDSVQCIELYDIFPRTISGVWQPFVSVAALGNPLQDQVVLHEEQGNTVLHLDLVTGAVRRLILSQDKQDEAPRKTSNWWNSKESQPGYKMCKEFAHKNWLLFYKENGNQLDVVDVLEGQVHTIHLPINLKAVFLVAEDRWLLVESKTDRKFLLTKPMHMGAEETGVCQLHAISEDAVSSGFGNNSGMEAVSPQEVSSDQLSNENLSAALGQKIVSPNRILCDTNTYANVIVGFPDLMSPNELYSFRRSLPITESRRPDMFFGSSKRTG-PAKRVNCVCLLDANQVVRALPPTQVPLAEVYPKDVTPPMSAAYLEVTDLNSKRLKYIPVPRSNSMSPYTVWISKVSDTDVVMAPLGSGGVVTVDMGGYVRLWETGLDHLQRSLLEWRNMIGSEDGRPVQITIERDSGLDVSSPKHGKIDAKNAPHVGGNQWAGGTGGRDTAGLGGKGGPYRLDAGHKVYQISQAEKDAVPDEVKRAARDMAEQAFKQRLKEIEMSEYDASTYDRFSGAVRRQVQSLRIILDSLQAKGKERQWLRNQALGELDDAKIIDGLTGEKSIYKRRGELEPELGSPQQKPKRLRVLADVSGSMYRFNGVDGRLERSMEAVCMVMEALESYEHKFKYDITGHSGDGFDIELVRCDKVPKNNKERLKVLKTMHAHSQFCMSGDYTLEGTEHAIREL-AHEEADEHFVIVLSDANLERYGISPDRFARVLTS-NPQVNAFAIFIGSLGDQADRLQKTLPAGRSFVAMDTKEIPQILQQIFTSTMLSSA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9PHH0-1", "uniprot_id": "M9PHH0_DROME", "id": "M9PHH0-1", "name": "von Willebrand factor A domain-containing protein 8", "aln": "--MLANLRACSGHLLHHSLRNARIPRRSWASTTAGKDQPEE--------------DSLTIGDVSVRLRKPKDPQLVPQQYADTSRIKETTDLKRRNELKYASDGTLQLSQSALHHLRWMLQKDALRQDMFLLGQPGPLRRQLAMQFLELTQREVEYVALSRDTTESDLKQRREINDRAAIFHDQGAVRAALNGRVLVLDGVEHAERNVLPILNNLLENREMHLESGKFLMSPERYDKLLEKHSREQLDEWGLLRVSEQFRVVALGLPTHKYKGTPLDPPLRSRFQSRNVTTYSYGELYEELQQEAPSVPGEQLKQLLTFALTLQQADP-VLQLPDFPIHNLALGVKMLAANPSLSLHDVISRIYPYQTMLKPDQKKRVEELLKKLDIQLVPSP----SIKKIEAQ-----SQENSLIHIKLDELQLNLPEGQ----IPTASTYFVDLPHQRQALASLLQAYAVGDVCLVGEKGVGKLTLTQELLRLLQQTSEPMMLYEDMTSRDIVQQRITSPQGDTVWRDSPLVRAAKSGSVAVLNGLHRLHKSTASVLQRLIHDRELQLCDGTTLLGANRYQALLQQG-FSKEELGKLGFLPIHESFRVVALAEPPRLGGGQPSWLTPELLSLFLYQELRPLRQSEEAELLAQLCGGDLPAGMDQLLKLAQLLRSSQDPLLQGLAGTLSTRQLLKLARRLAAYPESELSDVHEMLQNTFLARFMPALSRGALEQAIQQVGIKP---REIKLKSKKNQIAVEDNSLRIGSTRWPLGNPTQAQLSKVPHTLFYEMPQHVQLLERLLQDYLIGEHLLLVGNQGVGKNKLVDRLLELMQRPREYIQLHRDTTVHSLTLQATLKDGQVSYEDSALVQAVRTGHVLVVDEADKAPVNVTCILRTLVESGEMVLADGRRIVP-PGEGGRVPNSIETHPDFRLIVLANRPGFPFLGNDFFAALGDVFSCHAISNPDPESEIFLLQQYGPKVPIKTLRTLVNAFGELRTLADEGMLNYPYSTREVVSIVKHLERYPEENMSEVVGNVLDFDRYQPEALQQVTQVLAKHGIESYAEEEIQAIRKQ-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RILQASVNRHSGLGVSGPKFGKLDPKNEPHVGGNTWAGGSGGRDTAGLGGKGGPFRLDKGHKVHQLSDEEKADVPEEIKRAAREMNRKAFEDKLKEIKMSAHDHKLYAQFSEPNRKQVQQLKAVLEAMQTKSKERQWQKYQTHGDLDDTRLVEGITGEKNIYRRRAEANPWADHVQEKPNRLKLVVDVSGSMYRFNGYDGRLDRQLEAVVMVMEAFEGFEKKIVYDIIGHSGEGWEIPFVTAGSPPKNDKERFEAIRMMHAHSQFCWSGDSTVKAAREACSTLGAEQDYDNAIVVVLSDANLQRYGIAPKDLAMALKRGEPKVKGYAIFIGSLAEEADEINAEMPAGQSFVCMDLTKLPHILQQIFTSSLL---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . : *. * * . :::.**::* *: **:*:*** :: : .* :****::*** * **:**:* ******.:***:****::****:********:********. :*:: ** ***** :** *:*:*:*:*******:**********:**.*:****..******..*::::** * ::****:***:*****. :*.*.***********:*:: .: : : * ...*..*::.***:** ** . :. * *****:..*. .: :* * :.:.. : :*** :* : : ** :*::::: : .:* . :.: .:: :::* * * :. *:: :.: *.::*:: * *:**:* ** ** .::::: * . **:***:***:**::*** * *:***.** **** ** .*.:.:*:*:**:: .* :**.**:*****.* **: ** :** * :. ::.::* . .::*** ***::****** :*. .** **:*::*::: ::** ::** :: . .:::* .:: **.::** .**.:*******::.***: **.. .: : :: *:**:*:*::.:**: : : *: : : : * . * ** . *: .. : ***..***: **: ::: :*:*:::****************:***:*.*::*****:********::****.:::.* : ****.**:**: **:**:*******.******::***.***:********. . . * : *****::.***************.:***:*****:.**.*.:*: :*:****.** *..** ****** :**:* :.*********.*****:::* *.::.** **:*** *: : : : ..* *:** *: : *: : :* :::*.*. .** **.** *..* ****** ****:**************:*** ** *:*:*: ** **:::*****:* .:**:::****:** :* * :** . ::**: *: :*: :*:*.***** : *: *:***:::::*::*** **:**.: :* . *:**:**:::.********** * **:* :*** *****:*.:*.*: *** ****:*::* :* .. **::*:*:: :: ** ***** *** *::.:..* : . :: *: :*::******.**** * :* *. :*:*:.:*******.::* .:: :***:**:.** ..:*:********::* ", "identical_positions": 640, "similar_positions": 429, "identity": "32.99%" }, { "cls_id": "homologset.agr.RGD:1308773", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A5LHX3-1", "uniprot_id": "PSB11_HUMAN", "id": "A5LHX3-1", "name": "Proteasome subunit beta type-11", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------MALQDVCKWQSPDTQGPSPHLPRAGGWAVPRGCDPQTFLQIHGPRLAHGTTTLAFRFRHGVIAAADTRSSCGSYVACPASCKVIPVHQHLLGTTSGTSADCATWYRVLQRELRLRELREGQLPSVASAAKLLSAMMSQYRGLDLCVATALCGWDRSGPELFYVYSDGTRLQGDIFSVGSGSPYAYGVLDRGYRYDMSTQEAYALARCAVAHATHRDAYSGGSVDLFHVRESGWEHVSRSDACVLYVELQKLL--EPEPEEDASHAHPEPATAHRAAEDRELSVGPGEVTPGDSRMPAGTETV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LAS0-1", "uniprot_id": "A0ABK0LAS0_RAT", "id": "A0ABK0LAS0-1", "name": "Proteasome subunit beta type-11", "aln": "MLVPLLSHDLEAFACLTSHTTKLRRTQLSPSACIQSSMGSCWSPASTHLWGKYRMTDRRLYWGLLQVSQQWKVRLTGGVLERWEALQACPVSPWQFSEVGGDPSPANSQACSETEKKRSISSHGSLAGSGYSPASPQRPSSSPAGPGLKCCPAPSNFHSASGMALQDVCKWQAPDTHGLSLRLPQAGGWAVPRGCDPQTFLQIYGPRLAHGTTTLAFRFRHGVIAAADTRSSCGSYVACPASRKVIPVHRHLLGTTSGTSADCATWYRVLRRELRLRELREGQLPSVAGTAKLLSAMMSRYRGLDLCVATALCGWDHSGPALFYVYSDGTCLQGDVFSVGSGSPYAYGVLDRSYHYDMTVQEAYTLARCAVAHATHRDAYSGGSVDLFHVRESGWEYISRSDACVLYRELQEAQGFEQELEAKASEVLPEPATPQDARES-ELSVELEEVTPEDCKIIVKTETM", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **********:***:* * :**:******************:************************************** ******:********************:*****************.:*********:****************:*** ********* ****:****************.*:***:.****:*******************************::********* ***: * * * .**.. *****.: * *. **** **** *.:: . ***:", "identical_positions": 248, "similar_positions": 31, "identity": "53.45%" }, { "cls_id": "homologset.agr.RGD:1308774", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VWG0-1", "uniprot_id": "SHAWN_DROME", "id": "Q9VWG0-1", "name": "Solute carrier family 25 protein Shawn", "aln": "-----MATREACGQFAAASAAMAAAS---------------------------------------------------SQNPSKATMTDPRFRIRPLQQVASACTGAMVTACFMTPLDVIKTRLQAQ-------QQALLSNKCFLYCNGLMDHICPCG-PDTPNPAAAKP-----------APR-FSGTIDAFIKISRTEGIGSLWSGLSPTLISALPSTIIYFVAYEQFKARFTDI---HYKYTR-------------RPDTIAH----------DIPHPIPFLVPLLAGVSGRILAVTCVSPVELIRTKMQSQ---------RMTHAEMFGTIRQVVQSQG-VLGLWRGLPPTILRDVPFSGIYWTCYEYLKSSFG----VVEPT------FSFSFAAGAISGSVAATITTPFDVVKTHEQIEFGEKFIFSDN------------------PPKQVATK--SVAMRLASIYRMGGVPAIFSGLGPRLFKVAPACAIMISSFEYGKSFFYHYNIDQHNRSNQATKGPGS--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VI05-1", "uniprot_id": "Q9VI05_DROME", "id": "Q9VI05-1", "name": "Solute carrier family 25 member 40", "aln": "-----MSKEDSGASSAEANPAESEISMGRGPRPRSFTGGGGGGGTGGSGGSGGTSGGNNLKPERSAREDDAINRLTDSKSSHRKLLSDPRFQIRPLQQVISACTGAMITACFMTPLDVIKTRMQSQ-------QSP--AHKCFFYSNGLMDHLFASG-PNGSELASLRQ-----------RPQ-FSSSWDALMKISRHEGLAALWSGLGPTLVSALPSTIIYFVAYEQFKARYLQIYESHYNKSQ-------------EPRHLEIR---------DTKKSLPSVVPMMSGVTARICAVTVVSPIELVRTKMQAQ---------RQTYAQMLQFVRSVVALQG-VWGLWRGLRPTILRDVPFSGIYWPIYESLKQNLGH---GSQPS------FSLSFLAGVMAGTVAAIVTTPFDVVKTHEQIEFGERVIFTDS------------------PARDFGKK--STFSRLTGIYRTHGVRGLFAGCGPRLLKVAPACAIMISTFEYSKSFFFHYNVRHHNEALLLDNPKDTTVEDDDIE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IQW4-1", "uniprot_id": "Q8IQW4_DROME", "id": "Q8IQW4-1", "name": "", "aln": "MPPQLMSQMENGGEEEGCRLECKEMDP--------------------------------------------------LRLTTLILSADPRYRIKPMQQVVSALVGGLITTFVVTPLEVVKTRVQTQHAI---RQRPTVSKLCYVYHNGLMTHVCRSSDICVPKPGRDPQ-----------NLRPLRGAMDAFVKIVCTSGFSGLWAGLSPTLVSALPSTIIYFLTYEYIKNSLSHIYLVSQKFEESGMKDQVPGADGGDPLDQATRGINVSATAPVSTASLPYYVPMASGICSRTIVVTAITPIEMVRIKMQSE---------YMTYAELWRVLRSLIRQHG-ILGLWRGWPPTVMRDAPFSGTYWAVYEAIKRAFS----VTEPT------FLFSFLTGAISGAVATFVTMPFDLITTHTQIELGQDVLYEEIGAGTGAGTGTGAGARPKTPQSAVANSRPSVLSRMRQIYRLQGVRGLYVGVMPRMLRVVPACAIMISTFEYSKSFFFHYNLDLQEAAYRRSQ------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8BGP6-1", "uniprot_id": "S2540_MOUSE", "id": "Q8BGP6-1", "name": "Mitochondrial glutathione transporter SLC25A40", "aln": "-----MEPETEG--------------------------------------------------------------------------PPPTIPVTPLQQMIASCTGAVLTSLMVTPLDVVKIRLQAQ-------NNPFPKGKCFLYSNGLMDHMCVCE---EESKKAWYK-----------KPGNFRGTLDAFLKILRNEGIKSLWSGLPPTLVMAIPATVIYFTCYEQLSAFLKTKLG-----------------------------------------ENETRIPIVAGVVARFGAVTVISPLELIRTKVQSK---------KFSYKELYQFVSMRVSEDG-WISLWKGWAPTILRDVPFSAMYWYNYENLKRWLCEKSGLYEPT------FMINFTSGALSGSFAAVATLPFDVVKTQKQTQLWTNEYCKFP-----------------------APLDMSTWTIMKNIVADKGFSGLFTGLIPRLVKIVPACAIMISSYELGKSFFQKQNVESR--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q498U3-1", "uniprot_id": "S2540_RAT", "id": "Q498U3-1", "name": "Mitochondrial glutathione transporter SLC25A40", "aln": "-----MEPETEG--------------------------------------------------------------------------PPPTIQVTPLQQMMASCAGAVVTSLMVTPLDVVKIRLQAQ-------NNPFPKGKCFLYSNGLMDHICICE---EESKKAWYK-----------KPGNFHGTLDAFLKIVRNEGIKSLWSGLPPTLVMAVPATVIYFTCYEQLSTFLKTKLG-----------------------------------------ENETRIPIVAGIVARFGAVTMISPLELIRTKMQSK---------TFSYKELYQIVSMKVSEDG-WISLWKGWAPTILRDVPFSAMYWYNYENLRRWLCEKSDLYEST------FMINFTAGALSGSFAAVATLPFDVVKTQKQTQLWTHEYCKFP-----------------------EPLDMSTWSIMKNIVADRGFSGLFTGLIPRLVKIVPACAIMISSYELGKGFFQQQNVESR--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8TBP6-1", "uniprot_id": "S2540_HUMAN", "id": "Q8TBP6-1", "name": "Mitochondrial glutathione transporter SLC25A40", "aln": "-----MDPETRG--------------------------------------------------------------------------QE-IIKVTPLQQMLASCTGAILTSVIVTPLDVVKIRLQAQ-------NNPLPKGKCFVYSNGLMDHLCVCE---EGGNKLWYK-----------KPGNFQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALLRSKLG-----------------------------------------ENETCIPIVAGIVARFGAVTVISPLELIRTKMQSK---------KFSYVELHRFVSKKVSEDG-WISLWRGWAPTVLRDVPFSAMYWYNYEILKKWLCEKSGLYEPT------FMINFTSGALSGSFAAVATLPFDVVKTQKQTQLWTYESHKIS-----------------------MPLHMSTWIIMKNIVAKNGFSGLFSGLIPRLIKIAPACAIMISTYEFGKAFFQKQNVRRQQY------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DHC3-1", "uniprot_id": "S2540_DANRE", "id": "Q6DHC3-1", "name": "Mitochondrial glutathione transporter SLC25A40", "aln": "-----MSCQESS--------------------------------------------------------------------------PGPPGDITPFQQMMASCSGAIITSLLVTPLDVVKIRLQAQ-------KNPFPKGKCFVYCNGLMDHICVCE---NGNTKVWYK-----------APGHFSGTLDAFLKIIRMEGIRSLWSGLPPTLIMAVPATVIYFTCYDQLFALLKLKMG-----------------------------------------DRSDLAPLFAGAIARVGSATVISPLELIRTKMQSE---------KQSYREMSAVIRSALKNEG-LRSLWRGWGPTLLRDVPFSAMYWFNYEKGKWWLCKRYSCSEPT------VAITFTAGALSGSIASIITLPFDVVKTKRQVEMGELQTMKLS-----------------------TQVSSSTCSVMKRIVAENGVSGLFAGFMPRLIKVAPACAIMISTYEFGKAFFRKYNHQKEGQATASQHIISHTEKH----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P53320-1", "uniprot_id": "MTM1_YEAST", "id": "P53320-1", "name": "Mitochondrial carrier protein MTM1", "aln": "-----MSDRNTS------------------------------------------------------------------------------NSLTLKERMLSAGAGSVLTSLILTPMDVVRIRLQQQQMIPDCSCDGAAEVPNAVSSGSKMKTFTNVGGQNLNNAKIFWESACFQELHCKNSSLKFNGTLEAFTKIASVEGITSLWRGISLTLLMAIPANMVYFSGYEYIRDVSPIAST------------------------------------------YPTLNPLFCGAIARVFAATSIAPLELVKTKLQSIPRSSKSTKTWMMVKDLLNETRQEMKMVGPSRALFKGLEITLWRDVPFSAIYWSSYELCKERLWLDSTRFASKDANWVHFINSFASGCISGMIAAICTHPFDVGKTRWQISMMNNSDPKGG------------------------NRSRNMFKFLETIWRTEGLAALYTGLAARVIKIRPSCAIMISSYEISKKVFGNKLHQ----------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : ::: :: *.::*: .:**::*:: *:* * . .. * . : .: :*: ** .*: .** *: **: *:*:.::** *: : *: .* .* .* ::*:*::: *:*: :: : * .*::* *: **.***. ** ** : : .. . .* :* ::* .*: * ***: .*: * .: . : * *. .:: * .*:.:: *:******::* .* .* : ", "identical_positions": 69, "similar_positions": 92, "identity": "12.85%" }, { "cls_id": "homologset.agr.RGD:1308775", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZFB8-1", "uniprot_id": "D3ZFB8_RAT", "id": "D3ZFB8-1", "name": "", "aln": "MVFRFASFSD--SSPPEPSTQPKRPSVKWDLGS------DYEDVSNETTASGSDFRRQRTASQPDIGLHVQPQIYFLRPRSPIPKLLFSLINTSDANVKKMLPKSHLSRVIIRDNLNAQRIYEMEMKASDKTKRKMSYLYDHLKKKFMTDQLRKMMRWRRDSMSTQQYLDR---KRVC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CR34-1", "uniprot_id": "CE052_MOUSE", "id": "Q9CR34-1", "name": "Uncharacterized protein C5orf52 homolog", "aln": "MVLGLASFPESLSSQSETATQPRRPSVKWDLGS------DYRKGTEETTASGSNFRRERLDSQPDLGLHVQPQIYFLRPRSPLPKLLFSLMNTNDANVKKLLPKSHLSRVIIRDNLNAQRICEMEMKASDKTKRKMSYLYDHLKKKFMMDQLRKMIRWRRDSQSTQDYLDK---ERV-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NGY3-1", "uniprot_id": "CE052_HUMAN", "id": "A6NGY3-1", "name": "Uncharacterized protein C5orf52", "aln": "------------------MTQPTRPSVTCDQGSSTIGGTAAQATTSSSATSGSNYQRDRLGRRPEIGVGGQPQICFPRPRSAQQPVLFSLMNSSEAAMKKTLPKSHLSRVIIHDNRITQRIYEMEVSALEKTKKKISHYYEHLKKKFMTEQLRKLGRWREESVNSNRYLTFGIPPPV-", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *** ****. * ** . :..:::***:::*:* :*::*: **** * ****. :****:*:.:* :** ***********:** :*** ***:.* :***:*:*: *:******* :****: ***.:* .:: ** * ", "identical_positions": 78, "similar_positions": 39, "identity": "43.82%" }, { "cls_id": "homologset.agr.RGD:1308776", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8WWF8-1", "uniprot_id": "CAPSL_HUMAN", "id": "Q8WWF8-1", "name": "Calcyphosin-like protein", "aln": "-MAGTAR---------------HDREMAIQAKKKLT--TATDPIERLRLQCLARGSAGIKGLGRVFRIMDDDNNRTLDFKEFMKGLNDYAVVMEKEEVEELFRRFDKDGNGTIDFNEFLLTLRPPMSRARKEVIMQAFRKLDKTGDGVITIEDLREVYNAKHHPKYQNGEWSEEQVFRKFLDNFD-SPYDKDGLVTPEEFMNYYAGVSASIDTDVYFIIMMRTAWKL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6P8Y1-1", "uniprot_id": "CAPSL_MOUSE", "id": "Q6P8Y1-1", "name": "Calcyphosin-like protein", "aln": "-MAGTAR---------------HDREMAIQSKKKLS--TATDPIERLRLQCLARGSAGIKGLGRVFRIMDDNNNRTLDFKEFLKGLNDYAVVMEKEEAEELFQRFDRDGSGTIDFNEFLLTLRPPMSRARKEVIMKAFRKLDKTGDGVITIEDLREVYNAKHHPKYQNGEWTEEQVFRKFLDNFD-SPYDKDGLVTPEEFMNYYAGVSASIDTDVYFIIMMTTAWKL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GHT1-1", "uniprot_id": "A0A8I6GHT1_RAT", "id": "A0A8I6GHT1-1", "name": "", "aln": "-MAGTAR---------------HDREMAIQSKKKLS--TTTDPIERLRLQCLARGSAGIKGLGRVFRIMDDNNNRTLDFKEFLKGLNDYAVVMEKEEAEELFRRFDRDGNGTIDFNEFLVMLRPPMSRARKEVIMKAFRKLDKTGDGVITIEDLREVYNAKHHPKYQNGEWTEEQVFRKFLDNFD-SPYDKDGLVSEEDFVNYYAGVSASIDTDAYFVLMMMNSWRL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M1N594-1", "uniprot_id": "A0A8M1N594_DANRE", "id": "A0A8M1N594-1", "name": "", "aln": "-MAGTSR---------------HNREMMINAKKQLA--ECSDPIERLRLQCLSRGCAGIKGLGRTFRIMDDDNNRTLDLKEFIKGLNDYGVLMEKEEAINLFQQFDRDGSGQIDFDEFLITLRPPMSNARKEVVLQAFKKLDKTGDGVITVEDLKGVYDVRKHPKYLNGEWTEDQIFRKFLDSFD-SPDDKDGKVTKEEFMNYYSGVSASIDTDIYFILMMRNAWRLN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q86PF4-1", "uniprot_id": "Q86PF4_DROME", "id": "Q86PF4-1", "name": "EF-hand domain-containing protein", "aln": "MFLREIRTKGWSLKNPNCDLYTLEANMASQALRELTDGEDKDPITKLRLLCLSRGATGILGLGRAFRAMDDDGSKALNEEEFITGIRDTGLDVSEEEIKQMFATFDEDGSGSINMTEFLLKLRPPMPQSRLNIIDQAFNKMDRDEDGVITIQDLKNVYSVKEHPKYQSGEKSEDEILTDFLHNFEGGRGNLDGKITREEFVNYYATISASIDNDMFFDLMMRRAYVM-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VG26-1", "uniprot_id": "Q9VG26_DROME", "id": "Q9VG26-1", "name": "EF-hand domain-containing protein", "aln": "-MHREN-------------AYSKEAELKNLAKRELANGLDKDPIYKLRLQCFSRGATGILGLSRSFRVMDDDGSKSLSPEEFKKGVTDIGLDLTDSEIDEMFSRFDTDGSGNINMTEFLVKLRPPMNNSRISIIEKAFDKMDANGDGQITVTDLKNVYSVRDHPKYLSGEMTENQIFTQFLKNFEVGAPNPDGIVTREEFINYYATISASIDNDAYFDLMMRQAYKL-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :: : ::*: .*** :*** *::**.:** **.* ** ***:..::*. :** .*: * .: : ..* ::* ** **.* *:: ***: ***** .:* .:: :** *:* ** **: **: **..:.**** .** :*:::: .**..*: . : ** :: *:*:***: :*****.* :* :** :: : ", "identical_positions": 80, "similar_positions": 72, "identity": "35.09%" }, { "cls_id": "homologset.agr.RGD:1308777", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "F1LW91-1", "uniprot_id": "F1LW91_RAT", "id": "F1LW91-1", "name": "", "aln": "MTLHATRASTLLSWVNSLHVADPVETVLQLQDCSIFIKIINSIHDTKEGQQILQQPLPERLDFVCSFLQKNRKHPSSTQCLVSVQKVMEGSEMELAKMVMLFLYHSTMSSRNPRDWEQFEYGVQAELAVILKFMLDHEDSPNLTEDLENFLEK--VPSTYPSTLSEELSPPSHQAKRKIRFLEIQRIASSSSENNFLSGSPSSPVGDILQTPQFQMRRLKKQLADERNNRDELELELSESLKLLTEKDAQIAMMQQRIDHLALLNEKQAASPQEPSELEELRGKNESLTVRLHETLKQCQNLKTEKNQMDRKISQLSEENGDLSFKVREFANHLQQLQGAFNDLIEEHSKASQEWAEKQAHLESELSTALQDKKCLEEKSEILQEKISQLEDRAAQLQGSPAPEKGEVLGDALQLDTLKQEAAKLATDNTELQARVETLECERGKQEAQLLAERGHFEEEKRQLASLVADLQSSVSNLSQAKEELQQASQAQGAQLTAQLASLT----ALNATLQQQDQELTSLKEQAKKEQAQMLQTLQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEAARQDHAQQLATIVEAREASVRERDAARQQLETLEKEKDAKLESLQQQLQASNEARDTAQTSVTQAQREKAELSQKIGELHACIEAAHQEQRQAQAHVTELEAQLKAEQQKATEREKVVQEKVQLQEQLQALEETLKIVRGSLEEEKCRAADALKEQQRHATEMEAETRHLMEQREQEQKELEQEKAERKGLEARLQQLEEAHQAETEALRHELAGATAAQHGAESEREQLLREVESWQKRVEARQQEEARYGAMFQEQLMALKGEHGKIGQEEQKE-----AGEIHGEGQTGQQQSQLAQLHACLAKALQQVQEKEARAQKLLDDLSALREKMAATNKEVACLKALVLKAGEQQAAASHELK-EPPRAGNQESDWE-EEQARPLGSTQAALKAVQREAEQMGGELERLRAALMQSQGQQQEVRGQQEREVARLTQERGQAQADLAQEKAAKAELEMRLQNTLNEQRVEFAALQEALTHAMTEKEGKDQELAKLREQEAAQISELKALQQTLEELK----KKEKEHPTGGARGEDASGDGPGSQLHTPGKTEAPGPEVEALRAEISKLERQWQQQQQQVEGLTHSLESERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASSSARAAERSSALREEVQSLREEVEKQRVVSENLRQELASQAERAEESGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRFREEIEQSKQAAGGLQAELMRAQRELGELGSLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYESAKVKVLEERQRFQEERQKLTAQVEQLEVFHREQTKQVEELNKKLTESEQASRVQQQKLKAFQAQGGESQQEVQCLQTQLSELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELREQLQDLEQLQKDNKELRSETERLGRELQQAGLKTKEAEQACRHLTAQVRSLEAQVAHADQQLRDLGKFQVATDALKSREPQVKPQLDLSIDSLDLSLEEGTPCSVASKLPRTQPDGTSVPGEPASPISQRLPPKVESLESLYFTPIPARGQAPLETSLDSLGDAFPDSGRKTRSARRRTTQIINITMTKKLELEEPDSANSSFYSTQSAPASQANLRATSSTQSLARLGSPDDSNSALLSLPGYRPTTRSSARRSQTRTSSGAPHGRNSFYMGTCQDEPEQVDDWNRIAELQQRNRVCPPHLKTCYPLESRPALSLATITDEEMKTGDPRETLRRASMQPAQIAEGAGITTRQQRKRVSSETHQGPGTPESKKATSCFPRPMTPRDRHEGRKQNSTADAQKKAAPVLKQSDRRQSMAFSILNTPKKLGNSLLRRGTSKKTPAKVSPNPRSGTRRSPRIATTTAGAATAATT---PRAKGKAKH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q7G0-1", "uniprot_id": "NUMA1_MOUSE", "id": "E9Q7G0-1", "name": "Nuclear mitotic apparatus protein 1", "aln": "MTLHATRAATLLSWVNSLHVADPVETVLQLQDCSIFIKIINTIHDTKEGQQILQQPLPERLDFVCSFLQKNRKHPSSTQCLVSVQKVIEGSEMELAKMIMLFLYQSTMSSRNLRDWEQFEYGVQAELAVILKFMLDHEESLNLTEDLESFLEK--VPYTHASTLSEELSPPSHQTKRKIRFLEIQRIASSSSENNFLSGSPSSPMGDILQTPQFQMRRLKKQLADERSNRDDLELELSESLKLLTEKDAQIAMMQQRIDHLALLNEKQAASSQEPSELEELRGKNESLTVRLHETLKQCQNLKTEKSQMDRKISQLSEENGDLSFKVREFANHLQQLQGAFNDLIEEHSKASQEWAEKQARLENELSTALQDKKCLEEKNEILQGKLSQLEDQATRLQESPAPEKGEVLGDALQLDTLKQEAAKLATDNTQLQTRVETLECERGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQGAQLTAQLTSMT----GLNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQLAIVAEAREASLRERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEAHQAETEALRHELAEATASQHRAESECERLIREVESRQKRFEARQQEEARYGAMFQEQLMALKGE--KTGQEVQEE-----AVEIHSEGQPGQQQSQLAQLHASLAKAIQQVQEKEVRAQKLVDDLSALQEKMAATNKEVACLKTLVLKAGEQQETASLELLKEPPRAANRASDQLGEQQGRPFSSTHAAVKAMEREAEQMGGELERLRAALIKSQGQQQEERGQQEREVARLTQERGQAQADLAQEKAAKAELEMRLQNTLNEQRVEFAALQEALAHALTEKEGTDQELAKLRGQEAAQRTELKELQQTLEQLKIQLVKKEKEHPAGGASGEDASG--PGTQSETAGKTDAPGPELQALRAEISKLEQQCQQQQQQVEGLTHSLKSERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASNSARAAERSSALREEVQSLREEVEKQRVVSENSRQELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRFREELEQSKQAAGGLQAELMRAQRELGELGSLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYEGAKVKVLEERQRFQEERQKLTA--------------QVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQLQDLEELQKENKELRSEAERLGRELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLGKFQVATDALKSREPQVKPQLDLSIDSLDLSLEEGTPCSVASKLPRTQPDGTSVPGEPASPISQRLPPKVESLESLYFTPTPARGQAPLETSLDSLGDAFPDSGRKTRSARRRTTQIINITMTKKLELEEPDSANSSFYSTQSAPASQANLRATSSTQSLARLGSPDDGNSALLSLPGYRPTTRSSARRSQARMSSGAPQGRNSFYMGTCQDEPEQLDDWNRIAELQQRNRVCPPHLKTCYPLESRPTLSLATITDEEMKTGDPRETLRRASMQPAQIAEGVGITTRQQRKRVSSETHQGPGTPESKKATSCFPRPMTPRDRHEGRKQSSTADTQKKAAPVLKQADRRQSMAFSILNTPKKLGNSLLRRGASKKTPAKVSPNPRSGTRRSPRIATTTTGTATVATT---PRAKGKVKH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14980-1", "uniprot_id": "NUMA1_HUMAN", "id": "Q14980-1", "name": "Nuclear mitotic apparatus protein 1", "aln": "MTLHATRGAALLSWVNSLHVADPVEAVLQLQDCSIFIKIIDRIHGTEEGQQILKQPVSERLDFVCSFLQKNRKHPSSPECLVSAQKVLEGSELELAKMTMLLLYHSTMSSKSPRDWEQFEYKIQAELAVILKFVLDHEDGLNLNEDLENFLQKAPVPSTCSSTFPEELSPPSHQAKREIRFLELQKVASSSSGNNFLSGSPASPMGDILQTPQFQMRRLKKQLADERSNRDELELELAENRKLLTEKDAQIAMMQQRIDRLALLNEKQAASPLEPKELEELRDKNESLTMRLHETLKQCQDLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEEHSKATQEWLEKQAQLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQLGEAHQAETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKEECEKARQELQEAKEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPARAGDRQPEWLEEQQGRQFCSTQAALQAMEREAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQERGRAQADLALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEAAQIKELEELRQTVKQLKEQLAKKEKEHASG-----------SGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQQEQADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESEKSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAERAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRHREELEQSKQAAGGLRAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQLRSLEQLQKENKELRAEAERLGHELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLGKFQVATDALKSREPQAKPQLDLSIDSLDLSCEEGTPLSITSKLPRTQPDGTSVPGEPASPISQRLPPKVESLESLYFTPIPARSQAPLESSLDSLGDVFLDSGRKTRSARRRTTQIINITMTKKLDVEEPDSANSSFYSTRSAPASQASLRATSSTQSLARLGSPDYGNSALLSLPGYRPTTRSSARRSQAGVSSGAPPGRNSFYMGTCQDEPEQLDDWNRIAELQQRNRVCPPHLKTCYPLESRPSLSLGTITDEEMKTGDPQETLRRASMQPIQIAEGTGITTRQQRKRVSLEPHQGPGTPESKKATSCFPRPMTPRDRHEGRKQSTTEAQKKAAPASTKQADRRQSMAFSILNTPKKLGNSLLRRGASKKALSKASPNTRSGTRRSPRIATTTASAATAAAIGATPRAKGKAKH", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*******.::***************:**************: **.*:******:**:.*******************.:****.***:****:***** **:**:*****:. ******** :**********:****:. **.****.**:* ** * .**:.*********:**:*****:*::***** ********:**:**********************.***:*****:*. ******************:***********. **.******.******:**********:*****.******.************:****.******.*:*:* ******:*** ****:**.***:***********.**** *:****:: ::** .*. ********.***:*******.**::**:**:*** ** ***:***:*****.:**:**:**:**::*****:**********:*****:**:****::*:* ****:**:****:.**:***::***: **:*:****:****:********** *****:*.*::***:********* .* ****:****:* :***::**** **** ******.:*:***.*********:******:*: **:**:*:::***::.**:*:*** **::****:**:*:*.*** ******:**:*:**:.:******* ******:*** :*::**:* *:**:::*:****:*:* *******:*** ********.**:*** * *:** **** *:*::** : ::* * *****:**********:** * * ** *: . * *.* * .:**.:**:*** **:*:*******.***** ****:*:******.**** *::** ****** :** ** **.**.:: .: *:*.* : **:**::*::*******.*********::******* ****************:****** ****:*********:*********:*****:**:*****.******** **** .**: *:**:::** ******.:* .*:* .:.*:*:..**:::*****:****:* *:**:*.:.* :**::***.***:*.*************:****.*:* ******* *:*:*.*******:*********:******.*******************************:*****************.****.*********************.*****.*** ****:******** *******************:***********************************.***:**********:***:********* .****:.****:**************************************************************:****:***:::*****:***********.********************* *****.***:: :***:********.*** ******.* **:**.***********************************:*:***:.**:***:*****:*:****:**************:*****************************************.************** ***** *::*************************************** ***.*****:*******.* *************************::*************:*******.***************** .**********************: ***** ****************:******************************:***.************:********** *****.************ *.*******************************.:* :* *.. **:*************************:***: :*.***.**************:.:**.*: ******.**", "identical_positions": 1654, "similar_positions": 323, "identity": "77.8%" }, { "cls_id": "homologset.agr.RGD:1308778", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9H1J1-1", "uniprot_id": "REN3A_HUMAN", "id": "Q9H1J1-1", "name": "Regulator of nonsense transcripts 3A", "aln": "MRSEKEGAGGLRAAVAARGPSGREKLSALEVQFHRDSQQQEAETPPTSSSGCGGGAGKPREEKRTALSKVVIRRLPPGLTKEQLEEQLRPLPAHDYFEFFAADLSLYPHLYSRAYINFRNP--DDILLFRDRFDGYIFLDSKGLEYPAVVEFAPFQKIAKKKLRKKDAKTGSIEDDPEYKKFLETYCVEEEKTSANP--ETLLGEMEAKTRELIARRTTPLLEYIKNRKLEKQRIREEKREERRRRELEKKRLREEEKRRR-REEERCKKKETDKQKKIAEKEVRIKLLK--KPEKGEEPTTEKPKERGEEIDTGGGKQESCAPGAVVKARPMEGSLEEPQETSHSGSDKEHRDVE-----------RSQEQESEAQRYHVDDGRRHRAHHEPERLSRRSEDEQRWGKGPGQDRGKKGSQDSGAPG-EAMERLGRAQRCDDSPAPRKERLANKDRPALQLYDPGARFRARECGGNR-------------RICKAEGSGTGPEKREEAE-------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F7F115-1", "uniprot_id": "F7F115_RAT", "id": "F7F115-1", "name": "", "aln": "MRSE-EGAGGLGAVLSARGPSWREKLSGAETHFRRESTRNESAAPPAPALSESG-VGKPREEKRTALSKVVLRRLPPGLTKEQLEEQLRPLPAHDYFEVVAADLSLYPHLYSRAYINFRNP--DDILLFRDRFDGYIFIGNKGLEYPAVVEFAPFQKIAKKKVKKKDAKTGSIEDDPEYKQFLESYSLEEEKTSASP--ETLLGEIEAKTRELLARRTTPLLEYIKNRKLEKQRLREEKREERRRRELEKKRLREEEKRKR-REEDRCKRKDAEKQK-RAEKDVRIKLLK--KLETGEEATTEKHKERGEAVGAGEEKQE---------ARLVESQPETPGERLQDGSDKEPRDK------------RFREKEPETPRCH-DSCRKHSTHSEFARFSRRSEEEPKWRKGFTQDGGERG-QDGGVP---AAEQSSKEHKEYD--------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B0S733-1", "uniprot_id": "REN3A_DANRE", "id": "B0S733-1", "name": "Regulator of nonsense transcripts 3A", "aln": "MRSEKEQRTGS-----------RERGS-VEIQFR-DCQDNAAVNP------------KHKEEKKEIFSKVVIRRLPPSLSKDQLQEHLSPLPSFDYFEFFPADQSLYPHLFSRAYINFKNP--EDIIIFRDRFDGYVFIDNKGQEYPAVVEFAPFQKVSKKKLKKKDAKAGTIEEDPEYRRFLENYSCDEEKSMANP--ETLLGEIEAKTRELIAKRTTPLLEYIKNKKLEKQRIREEKREERRRRELEKKRQREEEKRKR-REEERQKRKEAEKQKKLSEKEIKIKLLK--KCDRDDDVDSDRLKDKGDSGETEKNRWE--------KPGGHTKSKDSKDNRSQMENDKEQREG------------HGRRQRDKDHRGRDEERKRQRHHYEFDKFMRRKE-ETKWGKGYCQDRAKKDQHHGYSYCPETGDKLGKEDREDMGS--RKERIRNKDRPAMQLYQPGARNRKRMGSGNKTFDFPPISPEHAGEHCYKTVIGTGSEKSADE--------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W1H3-1", "uniprot_id": "Q9W1H3_DROME", "id": "Q9W1H3-1", "name": "", "aln": "----------------------------MAETFAEEKPKEKSKASRR----------KDKKDKTNQIVKIVMRHLPPTMTEAQFLDQVGPLPENDSYYYCKADWSLGQEATCRAYIDMSSKDIGEVVQFRDRFDGYVFVDHKGVEYMAIVEYAPFQCFLKNKARNDDSKVNTIESEPHYQEFIKRLAQEREEASRMG--DVKI-DFNFERRTEEKVKSTPLLQYLANKKEKRREEARRRNEEKRKQREEQKLLRLAAQSDASKLKEAEGGGGGGDTKKPAKKDVKDPQSSGSQANDAKASRSKRRTERDQRRREEHEQRKLVKRDKKKDDGQGKQDKQDKQDKGKPSSGKQNKNSKSMDIVILKKANKPESNESLDVPSTSNAAEASKEKPATENTETPEAAVKVFTPAARGGRKEKRTGADKQPAGSAHETAEEAIKAAQFRASEERRIRNKDRPSIAIYQPKARIRASDELPQGAGGKDGSDGEASVVEEKTSKRNKRPNRRNKPKPKEVKECELETRRFSKSSESSTSVK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P48412-1", "uniprot_id": "UPF3_YEAST", "id": "P48412-1", "name": "Nonsense-mediated mRNA decay protein 3", "aln": "-------------------------MSNVAGELKNSEGKKK---------------GRGNRYHNKNRGKSKNETVDPKKNENKVNNATNATHNN-------SKGRRNNKKRNREYYNYKRK---ARLGKSTENEGFKLVIRLLPPNLTADEFFAILRDNNNDDGDKQDIQGKLKYS-DWCFFEGHYSSKVFKNSTYSRCNFLFDNLSDLEKCANFIKTCKFIDNKDNITIPDMKLSPYVKKFTQTSKKDAALVGTIEEDEIFKTFMNSMKQLNENDEYSFQDFSVLKSLE--KEFSKSIELENKIAERTERVLTELVGTG-------------DKVKNKNKKKKNKNAKKKFKEE---------------EASAKIPKKKRNRGKKKRENREKSTISKTKNSNVVIIEEAGKEVLKQRKKKMLLQEKLKISNSSQPQSS-------SAQTQPSFQPKENLFVPRVKILHRDDTKK----------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : : .. : * . : * .: :. : . :. . * * : : . :*: :: : *: .: ::. ..: ..:: . .: * . . : : : ::. : :: ::: * . . .: : . : : : . : :. . : . .: :: : : . : *: :: : . : . :: . . ", "identical_positions": 9, "similar_positions": 91, "identity": "1.69%" }, { "cls_id": "homologset.agr.RGD:1308779", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R1T1-1", "uniprot_id": "CHMP7_MOUSE", "id": "Q8R1T1-1", "name": "Charged multivesicular body protein 7", "aln": "MWSPEREAQAPTGGDPAGLLPPEWEEDEERMSFLFSAFKRSREVNSTDWDSKMGFWAPLVLSHSRRQG---VVRLRLRDLQEAFQRKGSVPLGLATVLQDLLRRGELQRESDFMAS---VDSS------WIS-WGVGVFLLKPLKWTLSNMLGDH-----KVPAEEVLVAVELLKEKAEEVYRLYQNSPLSSHPVVALSELSALCANSCPDERTFYLVLLQLQKEKRVTVLEQNGEKIVKFARGPHAKVSPVNDVDVGVYQLMQSEQLLSRKVESLSQESERCKEEARR-ACRAGKKQLALRSLKAKQRTEKRIEALHAKLDTVQGILDRIYASQTDQMVFNAYQAGVGALK-LSMKDVTVEKAESLVDQIQELCDTQDEVSQTLAGGVTNGLDFDSEELEKELDILLQDTTTE-------PLSLLETPQETT-------LYTNSVPKP--RILDAELEAELEKLSLSEG-GLIPSSKSPKRQLEPTL------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A7H9-1", "uniprot_id": "D4A7H9_RAT", "id": "D4A7H9-1", "name": "Charged multivesicular body protein 7", "aln": "MWSPEREAQAPTGGDPAGLLPPEWEEDEERMSFLFSAFKRSREVNSTDWDSKMGFWAPLVLSHSRRQG---VVRLRLRDLQEAFQRKGSVPLGLATVLQDLLRRGELQRESDFMAS---VDSS------WIS-WGVGVFLLKPLKWTLSNMLGDN-----KVPAEEVLVAVELLKEKAEEVYRLYQNSPLSSHPVVALSELSALCANSCPDERTFYLVLLQLQKEKRVTVLEQNGEKIVKFARGPHAKVSPVNDVDVGVYQLMQSEQLLSQKVESLSQESERCKEEARR-ACRAGKKQLALRSLKAKQRTEKRIEALHAKLDTVQGILDRIYASQTDQMVFNAYQAGVGALK-LSMKDVTVEKAESLVDQIQELCDTQDEVSQTLAGGVTNGLDFDSEELEKELDILLQDTTKE-------PLDLLENPHET--------LYTNSVPKP--RILDAELEAELEKLSLSEG-GLVPSSKSPKRQLEPTL------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8WUX9-1", "uniprot_id": "CHMP7_HUMAN", "id": "Q8WUX9-1", "name": "Charged multivesicular body protein 7", "aln": "MWSPEREAEAPAGGDPAGLLPPEWEEDEERMSFLFSAFKRSREVNSTDWDSKMGFWAPLVLSHSRRQG---VVRLRLRDLQEAFQRKGSVPLGLATVLQDLLRRGELQRESDFMAS---VDSS------WIS-WGVGVFLLKPLKWTLSNMLGDN-----KVPAEEVLVAVELLKEKAEEVYRLYQNSPLSSHPVVALSELSTLCANSCPDERTFYLVLLQLQKEKRVTVLEQNGEKIVKFARGPRAKVSPVNDVDVGVYQLMQSEQLLSRKVESLSQEAERCKEEARR-ACRAGKKQLALRSLKAKQRTEKRIEALHAKLDTVQGILDRIYASQTDQMVFNAYQAGVGALK-LSMKDVTVEKAESLVDQIQELCDTQDEVSQTLAGGVTNGLDFDSEELEKELDILLQDTTKE-------PLDLPDNPRNR--------HFTNSVPNP--RISDAELEAELEKLSLSEG-GLVPSSKSPKRQLEPTLKPL---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PBQ2-1", "uniprot_id": "CHMP7_DANRE", "id": "Q6PBQ2-1", "name": "Charged multivesicular body protein 7", "aln": "-MSVSVEKRS-------AWFPPDWDDDE-RMSFLFSAFKENRDVDCTDWDGKIDFWSPLIIEHCRRCG---SVCVNLQDLNENFRRKGSVPLGLSTVIQSMIRSGKVQKESDFAAN---VDSG------WLS-WGVGLLLVRPLKWTLSALLGSG-----RVPLEESFVVIELVKEKAAELLAAYRGSALSARSLLSFQELRSLSSHICPDESTLCMALLQLQREKHVTVSLHEGEKLVKFSQAGQGRVSPVSEVDLGIYQLQCSEKLLEERVEALGHEAEKCKQQAKS-LLKEGKKSQALRCLRGSKRVEKKADRLFAQLETVKGILDRIANSQTDRLVMQAYQAGVAALR-ISLKGVTVERAENLVDQIQELCDTQDEVNQTLASGAPDAGE-DSEDLEEELKSLMEKSVPENDLFPAVPTHPITPPRKTDLPDAAFVQFLPSVPNPGMNITDEELDRELRRLTVSDK-GLPRESVSPQRRLEPAQ------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P47048-1", "uniprot_id": "YJE9_YEAST", "id": "P47048-1", "name": "Uncharacterized protein YJL049W", "aln": "---------------------MKVDLPESRLPSLYRDFRPLKDLNPDGYEANISTWRDFFLQQYISNSNRIIFTIGTRTLQELTHEVYGVPKSIDIAIDVLVNEGNLIPMELFNLGGMYTDNSRKGFWKWVRSWKESTNMYKSRKDETNFYLREDKFIIKANLEKEYQRFHELLKRSVFMEASSITDLVFTRNEFVTTESLQSFFSTYDEETKNVFLHFIENYKHIIVSKDNVIKVIAAEVEDITSRFSKGITENDLRIASVKVGIININKQITRLRKEINESNIKLRGPEFNELPKRIRIEYKQARLLSEKHLSRLLKFQNNLAQVRTQIDTSATNAVLIQTLSESNEVIKSINGYIGSTEKVEDLLDEIKEGHDRTEEVNDLLAHYNKGQDEEAEEEIERELEQLELDEKNN------------NKEENKN----------QDLHEP-KESSSEDLLKRLNNLKINTNEGPVQDNENHDNEIRKIMMEEQPR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : * *:. *: *: :::: .::.::. * :.:.: . . : : *:* :. .** .: .:: ::. *:: . * . .*.. *: * . : :. * . * . :* **:*... . :: . .:: ..* :: : : .. : ::: :. *: .:. . :.: *: : .: . :..:: * :* :..: : : . * :. :. **: . * :.: : :* * *: ::::: . . .:: :. :.*:.*.*:*:*:* * :**.: ** . : .*::*.**. * . : .: .: :* . . :* .*..*.:. * .. . ...:. ", "identical_positions": 53, "similar_positions": 170, "identity": "10.73%" }, { "cls_id": "homologset.agr.RGD:1308781", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A096MJN4-1", "uniprot_id": "SEPT4_RAT", "id": "A0A096MJN4-1", "name": "Septin-4", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MIKHFLEDNSDDAELSKFVKDFPGSEPCHPTESKTRVARPQILEPRPQSPDLCDDDVEFRATLWS------QPSDSQQYFCPPAPLSPSSRPRSPWGKLDPYDSSED-DKEYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVNSLFLTDLYRDRKLLGAEERIMQT---------------------VEITKHAVDIEEKGVRLRLTIVDTPGFGDAVNN-TECWRPVAEYIDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPLDVEFMKALHQRVNIVPILAKADTLTPSEVDRKKCKIREEIEHFGIKIYQFPDCDSDEDEDFKLQDQALKESIPFAVIGSNTVVE-ARGRRVRGRLYPWGIVEVENPGHCDFVKLRTMLVRTHMQDLKDVTRETHYENYRAQCIQSMTR----LVVKERNR--NKLTRESGTDFPIPAVPPGTDPETEKLIREKDEELRRMQEMLHKIQRQMKETH---------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P28661-1", "uniprot_id": "SEPT4_MOUSE", "id": "P28661-1", "name": "Septin-4", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDHSLGWQGNSVPEDGT------------------------------------------------EAGIKHFLEDSSDDAELSKFVKDFPGSEPYHSAESKTRVARPQILEPRPQSPDLCDDDVEFRGSLWP------QPSDSQQYFSAPAPLSPSSRPRSPWGKLDPYDSSED-DKEYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVNSLFLTDLYRDRKLLGAEERIMQT---------------------VEITKHAVDIEEKGVRLRLTIVDTPGFGDAVNN-TECWKPVAEYIDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVDRKKCKIREEIEHFGIKIYQFPDCDSDEDEDFKLQDQALKESIPFAVIGSNTVVE-ARGRRVRGRLYPWGIVEVENPGHCDFVKLRTMLVRTHMQDLKDVTRETHYENYRAQCIQSMTR----LVVKERNR--NKLTRESGTDFPIPAVPPGTDPETEKLIREKDEELRRMQEMLHKIQRQMKETH---------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43236-7", "uniprot_id": "SEPT4_HUMAN", "id": "O43236-7", "name": "Septin-4", "aln": "MVKTNKPGAKVAVSAQRGSEVTTNTSPQQGHGYVLASSHRSAAVSLNPSHRRSEAAHPTTPHSASDYPRSVSLQSGPGHYAVPTPRGPETGPRTESSRHSSPHLKSQKTQTLASHASSRQWKVSPPREEAARRGSESKSGREVGHHASSIPDAKSTHQLSFQDQKNNLQSQILEDDPPSKVQNPQGVRVPRRILSYPKDEAVQTEPIQRITTTSEIRSPRSPSLLEHGSSCVSADYQTAQRRVPVEESETGPYGPIPSKPKALYRNMNLDSLLKLSVLKDSDGVHRVSARVDPESLHKYSAYPETKPSAKVLVSSQVESNVRTPIRGNSEVGRRVTISPGVQSVEPTHHVTVPSVSEGSHKSSMFVTPEPIYKQQTQKPPEITYMSQGPTPRYPELSQKPSIHAELELTPRPLPPRSLPRYGPDSSWWPLLNPEVETPQSQLTTPDFEPKCSPSLDLLLSGFKIDSSPFCEDLKFQREKASLSPPSPPKEFPSWAPLSEVPQTPKHTCKQPIQRFTAFFLDVSEEMYNRVIWWLKDEEIKRFLEDTTDDGELSKFVKDFSGNASCHPPEAKTWASRPQVPEPRPQAPDLYDDDLEFRPPSRP------QSSDNQQYFCAPAPLSPSARPRSPWGKLDPYDSSED-DKEYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVNSLFLTDLYRDRKLLGAEERIMQT---------------------VEITKHAVDIEEKGVRLRLTIVDTPGFGDAVNN-TECWKPVAEYIDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVDHKKRKIREEIEHFGIKIYQFPDCDSDEDEDFKLQDQALKESIPFAVIGSNTVVE-ARGRRVRGRLYPWGIVEVENPGHCDFVKLRTMLVRTHMQDLKDVTRETHYENYRAQCIQSMTR----LVVKERNR--NKLTRESGTDFPIPAVPPGTDPETEKLIREKDEELRRMQEMLHKIQKQMKENY---------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N7Z7-1", "uniprot_id": "A0A8M1N7Z7_DANRE", "id": "A0A8M1N7Z7-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPCTGS--------------------------------------------------ALSSLAIEDCEDAELAYTMRDLPPRAAHTFPENQTMDRQPDG-STAPHTPGTPTTTRPINRSFLGSEQELFRRGQLSSVSSLDSPLSPS-RPKSPWARFDPYDSAEDQDKEYVGFATLPNQVHRKSVKKGFAFTLMVAGESGLGKSTLVNSLFLTDLYKDRKMPNAEERIAQT---------------------VEITKHTVAIEEKGVKLRLTIVDTPGFGDAVNN-TESWRAIVDYIDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPIDVEFMKILHEKVNIVPVLAKTDSLTPEEVRKMKMKIREEIERFDIMIYQFPECESDEEDEFKLQQQELKDSVPFAVIGSNVQVE-SQGRRFRGRQYPWGLVEVENPEHSDFLKLRNMLVRTHMQDLKDVTRETHYENYRAQCIQNMTR----MVVRERKRSLNSRLRESPSDLPVPLVP--VDTETERLIWEKDEELRRMQEVLERIQEQMRQGHEDLPIN---------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q0KHR7-1", "uniprot_id": "Q0KHR7_DROME", "id": "Q0KHR7-1", "name": "Septin", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKHQPPPPPLPLSQPPTMG--------ATAAGGVASVISTMNGSSSS---------GIEAVKCRP-PIYPK--PKTP---------SFDKDRDYIGFATLPEQVHRKSVKRGFEFTLMVVGESGLGKSTLINSLFLGDLYKNRQMPNVEERIEKT---------------------TKVEKKTMDIEERGVRLRLTVVDTPGFGDAINC-EDSWRVCTQYIDEQFRQYFTDESGLNRRNIQDNRVHCCLYFVPPWGHSLRQMDLDLIRRLHRKVNIVLVIGKADCLNKQEVRKLKERILQDLEDNHIQLYQFPECDSDEDDDFKQQDRELKASIPFAVVGSNTILE-VAGKKVRGRQYPWGVVNVEDPEHSDFIKLRTFLISTHMQDLKDTTQDVHYENFRAQCISQISQ----HALRERGK--LKRDSISSTNGFDAAIS-----ETDRLLLQKDEEIRRMQDMLTQMQEKLKQTHLMEMKKNDSVIDV--------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32457-1", "uniprot_id": "CDC3_YEAST", "id": "P32457-1", "name": "Cell division control protein 3", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSLKEEQVSIKQDPEQEERQHDQFNDVQIKQESQDHDGVDSQYTNGTQNDDSERFEAAESDVKVEP---------GLGMGITSSQSEKGQVLPDQP-----EIKFIRRQINGYVGFANLPKQWHRRSIKNGFSFNLLCVGPDGIGKTTLMKTLFNNDDIEANLVKDYEEELANDQEEEEGQGEGHENQSQEQRHKVKIKSYESVIEENGVKLNLNVIDTEGFGDFLNNDQKSWDPIIKEIDSRFDQYLDAENKINRHSINDKRIHACLYFIEPTGHYLKPLDLKFMQSVYEKCNLIPVIAKSDILTDEEILSFKKTIMNQLIQSNIELFKPPIYSNDDAENSHLSER-LFSSLPYAVIGSNDIVENYSGNQVRGRSYPWGVIEVDNDNHSDFNLLKNLLIKQFMEELKERTSKILYENYRSSKLAKLGIKQDNSVFKEFDPISKQQEEKTLHEAKLAKLEIEMKTVFQQKVSEKEKKLQKSETELFARHKEMKEKLTKQLKALEDKKKQLELSINSASPNVNHSPVPTKKKGFLR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . . . . * * . *:***.**:* **:*:*.** *.*: .* .*:**:**:::** * . . : . **.: : .:: . ***.**:*.*.::** **** :* ..* . **.:* **: *. :**:.*:*:*:*.****: * ** *: :*:.::: ::.: *:: ::.*:* *. *: * * ::: * ::: * ..*: :: : .:: * *:*:**:*** :* *.:.*** ****:::*:: *.** *:.:*: .*::**: * . ***:*:. : .: ..:* . : : . : :: : :*:::::: : * :.:::: ", "identical_positions": 108, "similar_positions": 142, "identity": "10.08%" }, { "cls_id": "homologset.agr.RGD:1308783", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZWR9-1", "uniprot_id": "A0A8I5ZWR9_RAT", "id": "A0A8I5ZWR9-1", "name": "", "aln": "MCDGTLLPPLVLS-LLLLVWGLDPGTVVGDAAADVEVVLPRRLRPDDVHLQLLPGAAGLRQWRRPRASPGDPRAGPGERALLLHLPAFGRDLYLQLRRDLRFLSPGFEVEEAGVSGRSGHPAELCFYSGQVLGHPGSLVSLSACGAAGGLVGLIQLEQELVFIQPLNNSGGPFSRREHLIRRKWSSTSGLATKVEGPRQHCKVVTEEK-PRKGKLSWDWRERRNAIRLTNEHTVETLVVADADMVQYHGAEAAQRFILTVMNMVYNMFQHQSLGIKINIQVTKLVLLRQRPAKLSIGHHGERSLESFCHWQNEEYGGARYLGNNQVPGGKDDTPPVDAAVFVTRTDFCVHKDEPCDTVGIAYLGGVCSAKRKCVLAEDNGLNLAFTIAHELGHNLGMNHDDDHSSCAGRSHIMSGEWVKGRNPSDLSWSSCSRDDLENFLKSKVSTCLLITDPRSQHALRLPHKLPGMHYSANEQCQILFGTNATFCKNMEHLMCAGLWCLVEGDTSCKTKLDPPLDGTECGADKWCRAGECVSKTPIPEHVDGDWSPWSAWSMCSRTCGTGARFRQRKCDNPPPGPGGTHCQGASVEHAACENLPCPKGVPSFRDQQCQAHDRLSSKKRGLLTAMVVDDKPCELYCSPLGKESPLLVADRVLDGTPCGPYETDLCVYGRCQKIGCDGIIGSAAKEDRCGVCSGDGKTCRVVKGDFSHSRGTALKDSSKRSINSDWKIELPGEFQIAGTIVRYVRRGLWEKFSAKGPTTVPLHLMVLLFHDQNYGIHYEYTIPVNQSTENQSEPAKPQDALFLWTHSGWEGCSVQCGGGERRTIVSCTRIVNKTTTLVNDSDCPQASRPEPQVRRCNSHPCQSRWVAGQWSPCSATCEKGIQHREVTCVYQLQNGTHVTTRPIYCSEPRPTPVQSCEGQDCLSIWEASEWSECSANCGKGIRKRTVTCTNSQGKCDAATRPKAEEACEDYSGCYEWKTGDWSKCSSTCGKGLQSRVVQCMHKVTGRHGSECPTLSKPAAYRQCHQEVCNEKINVNTITSPRLAALTYKCTRDQWTVYCRVIREKSLCQDMRWYQRCCQTCRDFYANKMRQPPSPPSL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3YX90-1", "uniprot_id": "ATS17_MOUSE", "id": "D3YX90-1", "name": "A disintegrin and metalloproteinase with thrombospondin motifs 17", "aln": "MCDGTLLPPLVLS-LLLLVWGLDPGTAVGDAAADVEVVLPRRLRPEDVHLQLLPGAAGLRRWRRPRASPGGHRAGQGERALLLHLPAFGRDLYLQLHRDLRFLSPGFEVEEAGVSGRSGHPAELCFYSGRVLGHPGSLVSLSACGAAGGLVGLIQLEQEQVFIQPLNSSGGPFIGREHLIRRKWASTPSPATEVEGPRQRCKVVTEKK-PRKDHLSRDWRERRNAIRLTNEHTVETLVVADADMVQYHGAEAAQRFILTVMNMVYNMFQHRSLGIKINIQVTKLVLLRQRPAKLSIGHHGERSLESFCHWQNEEYGGARYLGNNQVPGGKDDTPPVDAAVFVTRTDFCVHKDEPCDTVGIAYLGGVCSAKRKCVLAEDNGLNLAFTIAHELGHNLGMNHDDDHSSCAGRSHIMSGEWVKGRNPSDLSWSSCSRDDLENFLKSKVSTCLLITDPRSQHALRLPHKLPGMHYSANEQCQILFGTNATFCKNMEHLMCAGLWCLVEGDTSCKTKLDPPLDGTECGADKWCRAGECVSKTPIPEHVDGDWSLWSAWSMCSRTCGTGARFRQRKCDNPPPGPGGTHCQGASVEHAACEKLPCPKGVPSFRDQQCQAHDRLSSKKRGLLTAVVVDDKPCELYCSPLGKESPLLVADRVLDGTPCGPYEADLCVYGRCQKIGCDGIIGSAAKEDRCGVCSGDGKTCRVVKGDFSHSRGTALKDSSKRSINSDWKIELPGEFQIAGTTVRYVRRGLWEKFSAKGPTTVPLHLMVLLFHDQNYGIHYEYTIPVNQSSENQSEPAKPQDALFLWTHSGWEGCSVQCGGGERRTIVSCTRIVNKTTTLVNDSDCPQASRPEPQVRRCNSHPCQSRWVTGQWSPCSATCEKGVQHREVTCVYQLQNGTHVTTRPIYCSEPRPTPVQSCEGQDCLSIWEASEWSECSANCGKGIQKRTVTCTNSQGKCDASTRPKAEEECEDYSGCYEWKTGDWSKCSSTCGKGLQSRVVQCMHKLTGRHGSECPTLSKPAAYRQCHQEVCNEKINVNTITSPRLAALTYKCTRDQWTVYCRVIREKNLCQDMRWYQRCCQTCRDFYADKMRQPPSPPSS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TE56-1", "uniprot_id": "ATS17_HUMAN", "id": "Q8TE56-1", "name": "A disintegrin and metalloproteinase with thrombospondin motifs 17", "aln": "MCDGALLPPLVLPVLLLLVWGLDPGTAVGDAAADVEVVLPWRVRPDDVHLPPLPAAPGPRRRRRPRTPPAAPRARPGERALLLHLPAFGRDLYLQLRRDLRFLSRGFEVEEAGAARRRGRPAELCFYSGRVLGHPGSLVSLSACGAAGGLVGLIQLGQEQVLIQPLNNSQGPFSGREHLIRRKWSLTPSPSAEAQRPEQLCKVLTEKKKPTWGRPSRDWRERRNAIRLTSEHTVETLVVADADMVQYHGAEAAQRFILTVMNMVYNMFQHQSLGIKINIQVTKLVLLRQRPAKLSIGHHGERSLESFCHWQNEEYGGARYLGNNQVPGGKDDPPLVDAAVFVTRTDFCVHKDEPCDTVGIAYLGGVCSAKRKCVLAEDNGLNLAFTIAHELGHNLGMNHDDDHSSCAGRSHIMSGEWVKGRNPSDLSWSSCSRDDLENFLKSKVSTCLLVTDPRSQHTVRLPHKLPGMHYSANEQCQILFGMNATFCRNMEHLMCAGLWCLVEGDTSCKTKLDPPLDGTECGADKWCRAGECVSKTPIPEHVDGDWSPWGAWSMCSRTCGTGARFRQRKCDNPPPGPGGTHCPGASVEHAVCENLPCPKGLPSFRDQQCQAHDRLSPKKKGLLTAVVVDDKPCELYCSPLGKESPLLVADRVLDGTPCGPYETDLCVHGKCQKIGCDGIIGSAAKEDRCGVCSGDGKTCHLVKGDFSHARGTALKDSGKGSINSDWKIELPGEFQIAGTTVRYVRRGLWEKISAKGPTKLPLHLMVLLFHDQDYGIHYEYTVPVNRTAENQSEPEKPQDSLFIWTHSGWEGCSVQCGGGERRTIVSCTRIVNKTTTLVNDSDCPQASRPEPQVRRCNLHPCQSRWVAGPWSPCSATCEKGFQHREVTCVYQLQNGTHVATRPLYCPGPRPAAVQSCEGQDCLSIWEASEWSQCSASCGKGVWKRTVACTNSQGKCDASTRPRAEEACEDYSGCYEWKTGDWSTCSSTCGKGLQSRVVQCMHKVTGRHGSECPALSKPAPYRQCYQEVCNDRINANTITSPRLAALTYKCTRDQWTVYCRVIREKNLCQDMRWYQRCCQTCRDFYANKMRQPP-PNS-", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****:*******. ************.************* *:**:**** **.*.* *: ****:.*. ** ********************:******* ********.: * *:*********:************************** ** *:*****.* *** *********: *.. :::.: *.* ***:**:* * .: * ************.****************************************:*************************************************************.* ******************************************************************************************************************:*******::********************** *****:*********************************************************** *.******************************** *******.**:******:***************.**:*****:************************************:****:*:*****************************::*******:********.* ******************* ***********:******.:************:********:***:::****** ****:**:****************************************************** ********:* ***********.*****************:***:**. ***:.*******************:***.****: ****:**********:***:*** ****************.*******************:*********:*****.****:*****::**.******************************.********************:****** * * ", "identical_positions": 970, "similar_positions": 85, "identity": "88.42%" }, { "cls_id": "homologset.agr.RGD:1308784", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5YBL7-1", "uniprot_id": "A0A8I5YBL7_RAT", "id": "A0A8I5YBL7-1", "name": "Poly [ADP-ribose] polymerase", "aln": "MAASRRSQHHHHHHQQQLQPAPGASAPPPPPPPPLSPGLAPGPTPASPTAGGLAPFASPRHGLALPEGDGSRDPPDRPRSPDPVDG--------AVCTVAATAAAPAAS--AAVGVAPSPAGGG---GNNSASSTSSPTSSSSSSPSSPGSSIAESPEAAGVGSTATLGPGAAGLGPGVPAVSGALRELLEACRNGDVSRVKRLVDAANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLADPSAKAVLT----EINLLPFYRSGNEEKLMALLTPLNVNCHASDGRK-------STPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRERLTYEFKGHSLLQAAREADLAKVKKTLALEIINFKQPQSHETALHCAVASLHPKRKQVAELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDSLGQTALHRAALAGHLQTCRLLLSYGSDPSIISLQGFTAAQMGNEAVQQILSESTPIRTSDVDYRLLEASKAGDLETVKQLCS--PQNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDLVKEGDTDIQDLLRGDAALLDAAKKGCLARVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLERGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLATADDIRALLIDAMPPEALPTCFKPQATVVSASLISPASTPSCLSAASSIDN--LTGPLAELAVG----------------GASNAGDGAAGAERKEGE---------VAGLDMNISQFLKSLGLEHLRDIFETEQITLDVLADMGHEELKEIGINAYGHRHKLIKGVERLLGGQQGTNPYLTFHCVNQGTILLDLAPEDKEYQSVEEEMQSTIREHRDGGNAGGIFNRYNVIRIQKVVNKKLRERFCHRQKEVSEENHNHHNERMLFHGSPFINAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPTHKDRSCYVCHRQMLFCRVTLGKSFLQFSTMKMAHAPPGHHSVIGRPSVNGLAYAEYVIYRGEQAYPEYLITYQIMKPEAPSQTATAAEQKT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PFX9-1", "uniprot_id": "TNKS1_MOUSE", "id": "Q6PFX9-1", "name": "Poly [ADP-ribose] polymerase tankyrase-1", "aln": "MAASRRSQHHHHHHQQQLQPAPGASAPPPPPPPPLSPGLAPGPTPASPTAGGLAPFASPRHGLALPEGDGSRDPPDRPRSPDPVDG--------AVCTVAAPAAVPAAS--AAVGVAPTPAGGGGGGGNNSASSASSPTSSSSSSPSSPGSSLAESPEAAGVGSTATLGAGAAGLGPGVPAVSGALRELLEACRNGDVSRVKRLVDAANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLADPSAKAVLTGEYKKDELLEAARSGNEEKLMALLTPLNVNCHASDGRK-------STPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRERLTYEFKGHSLLQAAREADLAKVKKTLALEIINFKQPQSHETALHCAVASLHPKRKQVAELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDSLGQTALHRAALAGHLQTCRLLLSYGSDPSIISLQGFTAAQMGNEAVQQILSESTPMRTSDVDYRLLEASKAGDLETVKQLCS--PQNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDLVKEGDTDIQDLLRGDAALLDAAKKGCLARVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLATADDIRALLIDAMPPEALPTCFKPQATVVSASLISPASTPSCLSAASSIDN--LTGPLTDLAVG----------------GASNAGDGAAGAERKEGE---------VAGLDMNISQFLKSLGLEHLRDIFETEQITLDVLADMGHEELKEIGINAYGHRHKLIKGVERLLGGQQGTNPYLTFHCVNQGTILLDLAPEDKEYQSVEEEMQSTIREHRDGGNAGGIFNRYNVIRIQKVVNKKLRERFCHRQKEVSEENHNHHNERMLFHGSPFINAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPTHKDRSCYICHRQMLFCRVTLGKSFLQFSTMKMAHAPPGHHSVIGRPSVNGLAYAEYVIYRGEQAYPEYLITYQIMKPEAPSQTATAAEQKT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95271-1", "uniprot_id": "TNKS1_HUMAN", "id": "O95271-1", "name": "Poly [ADP-ribose] polymerase tankyrase-1", "aln": "MAASRRSQHHHHHHQQQLQPAPGASAPPPPPPPPLSPGLAPGTTPASPTASGLAPFASPRHGLALPEGDGSRDPPDRPRSPDPVDGTSCCSTTSTICTVAAAPVVPAVSTSSAAGVAPNPAGSG---SNNSPSSSSSPTSSSSSSPSSPGSSLAESPEAAGVSSTAPLGPGAAGPGTGVPAVSGALRELLEACRNGDVSRVKRLVDAANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLADPSAKAVLTGEYKKDELLEAARSGNEEKLMALLTPLNVNCHASDGRK-------STPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRERLTYEFKGHSLLQAAREADLAKVKKTLALEIINFKQPQSHETALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAALAGHLQTCRLLLSYGSDPSIISLQGFTAAQMGNEAVQQILSESTPIRTSDVDYRLLEASKAGDLETVKQLCS--SQNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDLVKEGDTDIQDLLRGDAALLDAAKKGCLARVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLATADDIRALLIDAMPPEALPTCFKPQATVVSASLISPASTPSCLSAASSIDN--LTGPLAELAVG----------------GASNAGDGAAGTERKEGE---------VAGLDMNISQFLKSLGLEHLRDIFETEQITLDVLADMGHEELKEIGINAYGHRHKLIKGVERLLGGQQGTNPYLTFHCVNQGTILLDLAPEDKEYQSVEEEMQSTIREHRDGGNAGGIFNRYNVIRIQKVVNKKLRERFCHRQKEVSEENHNHHNERMLFHGSPFINAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPTHKDRSCYICHRQMLFCRVTLGKSFLQFSTMKMAHAPPGHHSVIGRPSVNGLAYAEYVIYRGEQAYPEYLITYQIMKPEAPSQTATAAEQKT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BJ18-1", "uniprot_id": "A0A8M2BJ18_DANRE", "id": "A0A8M2BJ18-1", "name": "Poly [ADP-ribose] polymerase", "aln": "MAVSRRS---SQHQQSSLQPSPRNAVIASPPPESPSAIIPDSASLLSPSATGAAECGAS---------------------------------------TMESAAASSAS-------------------ASSPDRPAPVTAAAAGGPSVLGSSSCSSISSSATAGSQSPGSGAASPGEAVCGAGGAFRELFEACRNGDVSRVKRLVDSVNVNAKDMAGRKSTPLHFAAGFGRKDVVEHLLQTGANVHSRDDGGLIPLHNACSFGHAEVVSLLLCSGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLADPSAKTVLTGEYKKDELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTSQKMLSTPLHLAAGYNRVRIVQLLLQYGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLLNCHGKSAVDVAPTPELKERLTYEFKGHSLLQAAREADMAKVKKT-AQEIISFKHPHSHDSALHCAVASPHPKRKQVTELLLRKGANIHEKNKDFMTPFHVAAERGHNDVLEVLQKHGAKVNAADTLGQTALHRAALAGHIQTCRLLLSYGADPSIVSLQGFTASQMGNEAVQQILNENVPPRNSDVDYRLLEAAKAGDLDTVKQLCS--PQNVNCRDLEGRHSTPLHFAAGYNRVAVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPSKKNRDGNMALDMVKDGDTDIQDLLRGDAALLDAAKKGCLARVQKLCSPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKFNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGANPTMKNQEGQTALDLATADDIRALLMDAMPPDALPSCFKPQATVLSAALISPASTPSCLSAASSIDN--LAGPLCDGASG----------------GAAGPADGASSTDRKEGDGALIQGNKLTAVLDMNISQFLKSLGLEHLRDIFEREQITLDVLADMGHEELKEIGINAYGHRHKLIKGIERLLGGQQGANPYLTFHCTNQGTVLIDLAVDDKEFQSVEEEMQSTIREHRDGGNAGGVFSRYNVIKIQKVVNKKLRERYTHRQKEIADENHNHHNERMLFHGSPFINAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPTHKDRSCYLCHRQMLFCRVTLGKSFLQFSAMKMAHAPPGHHSVIGRPSVNGLAYAEYVIYRGEQAYPEYLITYQIMKPDSTPQSSTGAEQKS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32TJT0-1", "uniprot_id": "A0AB32TJT0_DANRE", "id": "A0AB32TJT0-1", "name": "Poly [ADP-ribose] polymerase", "aln": "MATSRRT---AQQQQQQQQN------LSSPQRPDSSPLSPP----ESPTDTGGLAAGG----------------------------------------EAESIGDPELS-------------------AEIPAALLSTSSSSSSS-----SSTSSSTTGGGSSAGSTPDSGSASPGGSGCGTSGAFRELFEACRNGDVSRVKRLVDSVNVNAKDMAGRKSTPLHFAAGFGRKDVVEHLLQTGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLADPSAKAVLTGEYKKDELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTSQKMLSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELKERLTYEFKGHSLLQAAREADMTKVKKTLALEIINFKHPQTHETALHCAVVSPHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDILEVLQKHGAKMNAVDTLGQTALHRAALAGHLQTCRLLLSYGADPAIVSLQGFTAAQMGNEAVQQILNENIPVRNSDVDYRLLEAAKAGDLDTVKQLCS--PQNVNCRDLEGRHSTPLHFAAGYNRVAVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDMVKEGDTDIQDLLRGDAALLDAAKKGCLARVQKLCSLENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLATADDIRALLIDAMPPEALPSCFKPQATVVSASVISPGSTPSCLSAASSIDN--LAGPLTELAVS----------------GASGPADGATGTERKEGE---------ITILDMNISQFLKSLGLEHLRDIFEREQITLDVLADMGHEELKEIGINAYGHRHKLIKGIERLLGGQQGANPYLTFHCSGQGTVLIDLAPDDKEFQSVEEELQSTIREHRDGGNAGGVFSRYNILKIQKVVNKKLRERYTHRQKEIADENHNHHNERMLFHGSPFINAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPTHKDRSCYICHRQMLFCRVTLGKSFLQFSAMKMAHAPPGHHSVIGRPSVNGLAYAEYVIYRGEQAYPEYLITYQIIKPDSTPPSPAGAEQKS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VBP3-1", "uniprot_id": "TNKS_DROME", "id": "Q9VBP3-1", "name": "Poly [ADP-ribose] polymerase tankyrase", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------MANSSRSRAILSVNLDAVMANDPLRELFEACKTGEIAKVKKLITPQTVNARDTAGRKSTPLHFAAGYGRREVVEFLLNSGASIQACDEGGLHPLHNCCSFGHAEVVRLLLKAGASPNTTDNWNYTPLHEAASKGKVDVCLALLQHGANHTIRNSEQKTPLELADEATRPVLTGEYRKDELLEAARSGAEDRLLALLTPLNVNCHASDGRR-------STPLHLAAGYNRIGIVEILLANGADVHAKDKGGLVPLHNACSYGHFDVTKLLIQAGANVNANDLWAFTPLHEAASKSRVEVCSLLLSRGADPTLLNCHSKSAIDAAPTRELRERIAFEYKGHCLLDACRKCDVSRAKKLVCAEIVNFVHPYTGDTPLHLAVVSPDGKRKQLMELLTRKGSLLNEKNKAFLTPLHLAAELLHYDAMEVLLKQGAKVNALDSLGQTPLHRCARD--EQAVRLLLSYAADTNIVSLEGLTAAQLASDSVLKLLKN-----PPDSETHLLEAAKAGDLDTVRRIVLNNPISVNCRDLDGRHSTPLHFAAGFNRVPVVQFLLEHGAEVYAADKGGLVPLHNACSYGHYEVTELLVKHGANVNVSDLWKFTPLHEAAAKGKYDICKLLLKHGADPMKKNRDGATPADLVKESDHDVAELLRGPSALLDAAKKGNLARVQRLVTPESINCRDAQGRNSTPLHLAAGYNNFECAEYLLENGADVNAQDKGGLIPLHNASSYGHLDIAALLIKHKTVVNATDKWGFTPLHEAAQKGRTQLCSLLLAHGADAYMKNQEGQTPIELATADDVKCLLQDAMATSLSQQALSASTQSLTSSSPAPDATAAAAPGTSSSSSSAILSPTTETVLLPTGASMILSVPVPLPLSSSTRISPAQGAEANGAEGSSSDDLLPDADTITNVSGFLSSQQLHHLIELFEREQITLDILAEMGHDDLKQVGVSAYGFRHKILKGIAQLRSTTGIGN------NVNLCTLLVDLLPDDKEFVAVEEEMQATIREHRDNGQAGGYFTRYNIIRVQKVQNRKLWERYAHRRQEIAEENFLQSNERMLFHGSPFINAIVQRGFDERHAYIGGMFGAGIYFAEHSSKSNQYVYGIGGGIGCPSHKDKSCYVCPRQLLLCRVALGKSFLQYSAMKMAHAPPGHHSVVGRPSAGGLHFAEYVVYRGEQSYPEYLITYQIVKPD---DSSSGTEDTR", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . . . ....:***:***:.*::::**:*: . .***:* *****:*******:**::***.**: **.::: *:*** ****.********* *** **.**: ************ ***:***:.******: .***:: *:.*:*** :::.*** : :** *** *::*:****************: ************: **::** ***********************::**:**:: ** *** *** **********.**********:******:***.***:* *** **:**:::*:***.**:*.*:.*:::.** . **:.* :* : ::.** **.* . ****: *** ***: ::**** *:**:*:*** * * :*** *:***:** *:****.***.* *: ******.:*. *:**:*:**:*:..::* ::*.: .* : :****:*****:**::: . .******:************:***.**::**.***:*:* *******************:****:***.***:*****************:************ ****** . *:**:.* *: :**** :********* *****:* : *.*****:****************:* ******.******************:****:********.:* *******.****************:*******:. ********.::******::.** ***... .:...: :::: :* :*.:. ..:** .. : .* : . .:: . * .:: : .: : *:* **.* *.** ::** ******:**:***::**::*:.***.***::**: :* . * . *:*:** :***: :****:*:*******.*:*** *.***::::*** *:** **: **::*:::**. : ***************:::*********************:************** ***:***:***:* **:*:***:*******:*:*************:****..** :****:*****:**********:**: :.:.:*:. ", "identical_positions": 720, "similar_positions": 282, "identity": "52.71%" }, { "cls_id": "homologset.agr.RGD:1308785", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "O08603-1", "uniprot_id": "RAE1B_MOUSE", "id": "O08603-1", "name": "Retinoic acid early-inducible protein 1-beta", "aln": "----------------------------------MAKAAVTKRHHFMIQKLLILLSYGYTNGLDDAHSLRCNLTIKDPTPADPLWYEAKCFVGEILILHLSNIN-KTMTSGDPGETANATEVKKCLTQPLKNLCQKLRNKVSNTKVDTHKTNGYPHLQVTMIYPQSQGR-----TPSATWEFNISDSYFFTFYTENMSWRSANDESGVIMNKWKDDGEFVKQLKFL-IHECSQKMDEFLKQSKEKPRSTSRSPSITQLTSTSPLPPPSHSTSKKGFISVGLIFIS----------------------LLFAFAFAM---------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9JI58-1", "uniprot_id": "RAE1D_MOUSE", "id": "Q9JI58-1", "name": "Retinoic acid early-inducible protein 1-delta", "aln": "----------------------------------MAKAAVTKRHHFMIQKLLILLSYGYTNGLDDAHSLRCNLTIKAPTPAD----EVKCFVGEILILHLSNIN-KTMTSGDPGETANATEVGECLTQPLKDLCQKLRDKVSNTKVDTHKTNGYPHLQVTMIYPQSQGQ-----TPSATWEFNISDSYFFTFYTEIMSWRSANDESGVIMNKWKDDGEFVKQLKFL-IHGCSQKMDEFLKQSKEKPRSTSRSPSITQLTSTSPLPPTSHSTSKKGFISVGLIFIS----------------------LLFAFAFAM---------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O08602-1", "uniprot_id": "RAE1A_MOUSE", "id": "O08602-1", "name": "Retinoic acid early-inducible protein 1-alpha", "aln": "----------------------------------MAKAAVTKRHHFMIQKLLILLSYGYTNGLDDAHSLRCNLTIKDPTPADPLWYEAKCLVDEILILHLSNIN-KTMTSGDPGETANATEVGECLTQPLKDLCQKLRNKVSNTKVDTHKTNGYPHLQVTMIYLQSQGQ-----IPSATWEFNISDSYFFTFYTENMSWRSANDESGVIMNKWKDDGEFVKRLKFL-IPECRQEVDEFLKQPKEKPRSTSRSPSITQLTSTSPLPPPSHSTSKKGFISVGLIFIS----------------------LLFAFAFAM---------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O08604-1", "uniprot_id": "RAE1C_MOUSE", "id": "O08604-1", "name": "Retinoic acid early-inducible protein 1-gamma", "aln": "----------------------------------MAKAAVTKRHHFMIQKLLILLSYGYTNGLDDAHSLRCNLTIKAPTPADPLWYEAKCLVDEILILHLSNIN-KTMTSGDPGETANATEVGECLTQPVNDLCQKLRDKVSNTKVDTHKTNGYPHLQVTMIYPQSQGQ-----TPSATWEFNISDSYFFTFYTENMSWRSANDESGVIMNKWNDDGDLVQRLKYF-IPECRQKIDEFLKQSKEKPRSTSRSPSITQLTSTSPLPPPSHSTSKKGFISVGLIFIS----------------------LLFAFAFAM---------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9CZQ6-1", "uniprot_id": "RAE1E_MOUSE", "id": "Q9CZQ6-1", "name": "Retinoic acid early-inducible protein 1-epsilon", "aln": "----------------------------------MAKAAVTKRHHFMIQKLLILLSYGYTNGLDDAHSLRCNLTIKDPTSADLPWCDVKCSVDEITILHLNNIN-KTMTSGDPGKMANAT--GKCLTQPLNDLCQELRDKVSNTKVDTHKTNGYPHLQVTMIYPQSQGQ-----TPSATWEFNISDSYFFTFYTENMSWRSANDESGVIMNKWKDDGDLVQQLKYF-IPQCRQKIDEFLKQSKEKPRSTSRSPSITQLTSTSPLPPPSHSTSKKGFISVGLIFIS----------------------LLFAFAFAM---------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZTU3-1", "uniprot_id": "A0A8I5ZTU3_RAT", "id": "A0A8I5ZTU3-1", "name": "", "aln": "--------------------------------MTMAKRGTTKCNLSLSLGLLLLLNFLGTAMLEDVHSLSCNLIIRSPTKAEPLWYEGQCSMDGIDFLSFNNVN-KTMPLGNQEKMANATEVWTCVTQWIDLLGQDLRDKVSEIKGDTTKTSGHPTLWVTMLSNHSHRH-----IIGASCVFNISENYSFILDLKTMKWKLINPVPEDIMKEWKDDATLMKHLNLS-IAECSQKFNEFLNQHEERTRSRTRAPDIAQPPPTRQFPYKEVLIPVVLIIFIIFICICV--------KRMCCTQGGRELQLLKDYYINLHKPQRNEGLEETKG---------EVPNQSTKMLSQEEDPKTLGGPRRASESVELELQMFSSTGS-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5VY80-1", "uniprot_id": "ULBP6_HUMAN", "id": "Q5VY80-1", "name": "UL16-binding protein 6", "aln": "-----------------------------------MAAAAIPALLLCLPLL-FLLFGWSRARRDDPHSLCYDITVIPKFRPGPRWCAVQGQVDEKTFLHYDCGNKTVTPVSPLGKKLNVTMAWKAQNPVLREVVDILTEQLLDIQLENYTPKEPLTLQARMSCEQKAEG-----HSSGSWQFSIDGQTFLLFDSEKRMWTTVHPGARKMKEKWENDKDVAMSFHYISMGDCIGWLEDFLMGMDSTLEPSAGAPLAMSSGTTQLRATATTLILCCLLIIL------------------------------PCFILPGI--------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9BZM5-1", "uniprot_id": "ULBP2_HUMAN", "id": "Q9BZM5-1", "name": "UL16-binding protein 2", "aln": "-----------------------------------MAAAAATKILLCLPLL-LLLSGWSRAGRADPHSLCYDITVIPKFRPGPRWCAVQGQVDEKTFLHYDCGNKTVTPVSPLGKKLNVTTAWKAQNPVLREVVDILTEQLRDIQLENYTPKEPLTLQARMSCEQKAEG-----HSSGSWQFSFDGQIFLLFDSEKRMWTTVHPGARKMKEKWENDKVVAMSFHYFSMGDCIGWLEDFLMGMDSTLEPSAGAPLAMSSGTTQLRATATTLILCCLLIIL------------------------------PCFILPGI--------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6H3X3-1", "uniprot_id": "ULBP5_HUMAN", "id": "Q6H3X3-1", "name": "UL-16 binding protein 5", "aln": "-----------------------------------MAAAASPAFLLRLPLL-LLLSSWCRTGLADPHSLCYDITVIPKFRPGPRWCAVQGQVDEKTFLHYDCGSKTVTPVSPLGKKLNVTTAWKAQNPVLREVVDILTEQLLDIQLENYIPKEPLTLQARMSCEQKAEG-----HGSGSWQLSFDGQIFLLFDSENRMWTTVHPGARKMKEKWENDKDMTMSFHYISMGDCTGWLEDFLMGMDSTLEPSAGAPPTMSSGTAQPRATATTLILCCLLIMCLLICSRHSLTQSHGHHPQSLQPPPHPPLLHPTWLLRRVLWSDSYQIAKRPL---------SGGHVTRVTLPIIGDDSHSLPCPLALYTINNGAARYSEPLQVSIS-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9BZM6-1", "uniprot_id": "ULBP1_HUMAN", "id": "Q9BZM6-1", "name": "UL16-binding protein 1", "aln": "-----------------------------------MAAAASPAFLLCLPLL-HLLSGWSRAGWVDTHCLCYDFIITPKSRPEPQWCEVQGLVDERPFLHYDCVNHKAKAFASLGKKVNVTKTWEEQTETLRDVVDFLKGQLLDIQVENLIPIEPLTLQARMSCEHEAHG-----HGRGSWQFLFNGQKFLLFDSNNRKWTALHPGAKKMTEKWEKNRDVTMFFQKISLGDCKMWLEEFLMYWEQMLDPTK--PPSLAPGTTQPKAMATTLSPWSLLIIF------------------------------LCFILAGR--------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9BZM4-1", "uniprot_id": "ULBP3_HUMAN", "id": "Q9BZM4-1", "name": "UL16-binding protein 3", "aln": "-----------------------------------MAAAASPAILPRLAILPYLLFDWSGTGRADAHSLWYNFTIIHLPRHGQQWCEVQSQVDQKNFLSYDCGSDKVLSMGHLEEQLYATDAWGKQLEMLREVGQRLRLELADTELEDFTPSGPLTLQVRMSCECEADG-----YIRGSWQFSFDGRKFLLFDSNNRKWTVVHAGARRMKEKWEKDSGLTTFFKMVSMRDCKSWLRDFLMHRKKRLEPTA--PPTMAPGLAQPKAIATTLSPWSFLIIL-------------------------------CFILPGI--------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8TD07-1", "uniprot_id": "RAE1E_HUMAN", "id": "Q8TD07-1", "name": "Retinoic acid early transcript 1E", "aln": "--------------------------------MRRISLTSSPVRLLLFLLLLLIALEIMVGG----HSLCFNFTIKSLSRPGQPWCEAQVFLNKNLFLQYNSDNNMVKPLGLLGKKVYATSTWGELTQTLGEVGRDLRMLLCDIKPQIKTS-DPSTLQVEMFCQREAER-----CTGASWQFATNGEKSLLFDAMNMTWTVINHEASKIKETWKKDRGLEKYFRKLSKGDCDHWLREFLGHWEAMPEPTVSPVNASDIHWSSSSLPDRWIILGAFILLVLMG------------------------IVLICVWWQNGEWQAGLWPLRTS--------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N5I1-1", "uniprot_id": "A0A8M1N5I1_DANRE", "id": "A0A8M1N5I1-1", "name": "", "aln": "------------------------MALATYIVG--QTPFPEFSVVVMLDDLQLAYYDSIGWKTIYRSGSDSKYYDEEQSDAGIVFRDMFYDMKDRAFYLKDHQN-HTDGVHVHQRLVGCELLNNEKTGPLHYWDAFGGQNMEEFIFDTEKHTIQVKMPWVITWDQLKRLHENFMYDNVYHPICIKTLRRYLNMEKKNVMRKVKPRVRLMQKKLSDSQGLQISCLATGFYPRHINLTLFRDAELVDDDQITGGEILPNGDGTYQMRKSLIVSEEELQKGHKYNCTANYLNLDNKMDIVFDVAESDPGSFSVSVVMGVLVFVGLS--------------------VLSITALIMRRKRRDTGSVSGTSQNQYVYAQTSVQDAT----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3AVG2-1", "uniprot_id": "A0A8M3AVG2_DANRE", "id": "A0A8M3AVG2-1", "name": "", "aln": "MKTMLFLLYLLSCLTFTDAGFHSLLVLATYVDG--QTPFPELSVVVMLDDVQIIYYDSDTWRVFHRSPSDSKYYDEDQSDADAVFHDTYDEMKYRVLHLKNQLN-HTDGITVLQRIVGCELFN-DKPGIYHLWDAHDGKTIEKFTFNIYNHEFQLKNQWFRTWDQVMIQQKRIVHENIYYPVCIKVLRRYLNVEKNSVMRKVKPRVRLMKKKLPDSQGLQISCLATGFYPRHINLTLFRDAEPVDDDQIIGGEILPNGDGMYQMRKSLIVSKEELDEGHEYTCTMKHLNLDNKLDIVFDVSGTVPGCFSVSVVISVLVFMCVS--------------------VFIITKLIMRRKRQDTG--RGSEKCDYSPTISSSQDEI----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58J1X9-1", "uniprot_id": "A0AC58J1X9_DANRE", "id": "A0AC58J1X9-1", "name": "", "aln": "MMYLVLAVCILSASVFSQSGSHSLWVFATFLTGDISVQFPEFSAVVMLDDIVIGHYNADDRSFVPSTVQESVNIT-EQITISTVCKGIHEGMKTKAYYLIDYLN-HTRGLHVQQRLVGCELLQ-NEPGQMMTLEAFNGESGFERRYDIQ-GDQQTHWKWPVIKSRAQLEYDAWLYAHFYRPLCINQLRKYLKKEKKRVMARVKPRVRVIQRTCSKTGKIQMTCLATGFYPRHINLTLLQDGQPVNEERVMGGELLPNADGTYQMRKSVELSAEEQRERRTYTCTVNHLSLDNKLDISIEPG-LDPVIIFPSVLLLLCVFGVLAGFLMWRKKYKQPEQVHKHFHCFTDKLIFIRYKHCSLRFLIVFLPLQVTYTPTSATDQTTEQSQL----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58IU49-1", "uniprot_id": "A0AC58IU49_DANRE", "id": "A0AC58IU49-1", "name": "", "aln": "-MDKILLLFLFLLPTSAPKGSHSLCLLATYIKG--PSPFPELSGVMMLDDIPLLYYNGDTKTFFMRGNTTAEDNVFDANAFLSIIGHIQSSFVDRWGLASRDLN-KTDRIFTLQQLVLCELSEDGEHGKMISRDAVEGTTTDELQHVDHKFTYKHTLNVSAYLIDFYLELTKSLHKTLFQPTCFKTLSGYLIQRRNQINRKVKPKVRLFKKELS--SGFIVSCLATGFYPRHINLTLLRDGQPVSDHDVTGGDLLPNGDGTYQMRKSLEIRAEE-RQKHKYSCSVKHLSLDNKLHVDLDFDHGEPFKLLIPTVLVVLTICSTFIKERGRK-------------VCDEVDSYVRPGATWNGEWLQESCGAMTRVFMHVAKGAFLDKLYDVSF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . . . . . : : . . . : ", "identical_positions": 0, "similar_positions": 13, "identity": "0.0%" }, { "cls_id": "homologset.agr.RGD:1308787", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZZ44-1", "uniprot_id": "D3ZZ44_RAT", "id": "D3ZZ44-1", "name": "", "aln": "MAGH-----GWG----APWVLVAAATLLHACGLAQGDCWLIEGDKGFVWLAICSQNQPPYEAIPQQINNTIVDLRLNENRIRSVQYASLSRFGNLTYLNLTKNEIGYIEDGAFSGQFNLQVLQLGYNRLRNLTEGMLRGLSKLEYLYLQANLIEVVMASAFWECPNIVNIDLSMNRIQQLGSGTFAGLTKLSVCEIYSNPFYCSCELLGFLRWLAAFTNATQTHDRVQCESPPVYAGYFLLGQG-RHGHQRSILSKLQSVCTEGSYTAEVLGPPRPVPGRSQPGHSPPPPPP-EPSDMPCADDECFSGDGTTPLVVLTTLVPQTEARPSMKVKQLTQNSATIMVQLPSPFNRMYTLEQYNNSKSFTVSKLTQPQEEIRLTNLYTLTNYTYCVVSTSSGTHHNHTCLTICLPKPPSPPGPVPSPSTATHYIMTILGCLFGMVLVLGAVYYCLRKRRRQEEKHKKAV-AAAAGSLKKTIIELKYGPEIEAPGLAPLTQGPLLGPEAVTRIPYLPAATSDVEQYKLVESGETPKATKGNYIEVRTGEPPERRGCELSRPAPETQSSVAEISTIAKEVDRVNQIINNCIDALKSESTSFQGAKSGAVSAAEPQLVLLSEPLASKHSFLSPVYKDAFGHGGLQRHHSVEAATGPPRASTSSSGSARSPRTFRAETAGAHKAPATETKYIEKSSPVPETILTVTPAATVLRAEADKSRQYGEHRHSYPGSHPAEPPAPP--PPPPTHEGLGGRKASILEPLTRPRPRDLVYSQLSPQYHNLSYSSSPEYTCRASPSIWERLRLSRRRHKDDAEFMAAGHALRKKVQFAKDEDLHDILDYWKGVSAQHKS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C8T7-1", "uniprot_id": "ELFN1_MOUSE", "id": "Q8C8T7-1", "name": "Protein ELFN1", "aln": "MAGH-----GWG----TAWVLVAAATLLHAGGLAQGDCWLIEGDKGFVWLAICSQNQPPYEAIPQQINNTIVDLRLNENRIRSVQYASLSRFGNLTYLNLTKNEIGYIEDGAFSGQFNLQVLQLGYNRLRNLTEGMLRGLSKLEYLYLQANLIEVVMASAFWECPNIVNIDLSMNRIQQLGSGTFAGLTKLSVCEIYSNPFYCSCELLGFLRWLAAFTNATQTHDRVQCESPPVYAGYFLLGQG-RHGHQRSILSKLQSVCTEGSYTAEVLGPPRPVPGRSQPGHSPPPPPP-EPSDMPCADDECFSGDGTTPLVILTTLVPQTEARPSMKVKQLTQNSATIMVQLPSPFNRMYTLEQYNNSKSFTVSKLTQPQEEIRLTNLYTLTNYTYCVVSTSSGTHHNHTCLTICLPKPPSPPGPVPSPSTATHYIMTILGCLFGMVLVLGAVYYCLRKRRRQEEKHKKAV-AAAAGSLKKTIIELKYGPEIEAPGLAPLTQGPLLGPEAVTRIPYLPAATSDVEQYKLVESSETPKATKGNYIEVRTGEPQERRGCELSRPG-EPQSSVAEISTIAKEVDRVNQIINNCIDALKSESTSFQGAKSGAVSAAEPQLVLLSEPLASKHSFLSPVYKDAFGHGGLQRHHSVEAAPGPPRASTSSSGSARSPRTFRAEATGTHKAPATETKYIEKSSPVPETILTVTPAATVLRAEADKSRQYGEHRHSYPGSHPAEPPAPP--PPPPTHEGLGGRKASILEPLTRPRPRDLVYSQLSPQYHNLSYSSSPEYTCRASPSIWERLRLSRRRHKDDAEFMAAGHALRKKVQFAKDEDLHDILDYWKGVSAQHKS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0C7U0-1", "uniprot_id": "ELFN1_HUMAN", "id": "P0C7U0-1", "name": "Protein ELFN1", "aln": "MAGR-----GWG----ALWVCVAAATLLHAGGLARADCWLIEGDKGFVWLAICSQNQPPYEAIPQQINSTIVDLRLNENRIRSVQYASLSRFGNLTYLNLTKNEIGYIEDGAFSGQFNLQVLQLGYNRLRNLTEGMLRGLGKLEYLYLQANLIEVVMASSFWECPNIVNIDLSMNRIQQLNSGTFAGLAKLSVCELYSNPFYCSCELLGFLRWLAAFTNATQTYDRMQCESPPVYSGYYLLGQG-RRGHR-SILSKLQSVCTEDSYAAEVVGPPRPASGRSQPGRSPPPPPPPEPSDMPCADDECFSGDGTTPLVALPTLATQAEARPLIKVKQLTQNSATITVQLPSPFHRMYTLEHFNNSKASTVSRLTKAQEEIRLTNLFTLTNYTYCVVSTSAGLRHNHTCLTICLPRLPSPPGPVPSPSTATHYIMTILGCLFGMVLVLGAVYYCLRRRRRQEEKHKKAASAAAAGSLKKTIIELKYGPELEAPGLAPLSQGPLLGPEAVTRIPYLPAAG-EVEQYKLVESADTPKASKGSYMEVRTGDPPERRDCELGRPGPDSQSSVAEISTIAKEVDKVNQIINNCIDALKSESTSFQGVKSGPVSVAEPPLVLLSEPLAAKHGFLAPGYKDAFGHS-LQRHHSVEAA-GPPRASTSSSGSVRSPRAFRAEAVGVHKAAAAEAKYIEKGSPAADAILTVTPAAAVLRAEAEKGRQYGEHRHSYPGSHPAEPPAPPGPPPPPPHEGLG-RKASILEPLTRPRPRDLAYSQLSPQYHSLSYSSSPEYTCRASQSIWERFRLSRRRHKEEEEFMAAGHALRKKVQFAKDEDLHDILDYWKGVSAQHKS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BBN8-1", "uniprot_id": "A0A8M2BBN8_DANRE", "id": "A0A8M2BBN8-1", "name": "", "aln": "MASRRASEACYGGMVKSAFFWSVAIICLTYMGGVKGDCWLIEGEKGFVWLAICSQNQPPYEAIPQHINSTIVDLRLNENKIKSIHYSALSRFTNLTYLNLTKNEINYIEDGAFSAQFNLQVLQLGFNKLRNLTEGILRGLGKLQYLYLQANLIETVTPNAFWECPNIENIDLSMNRLQVLDGSTFTSLTKLTTCELYTNPFNCSCELLGFVKWLSVFPN--RTSERMVCDSPAGVSGYSLLSQNPTNPTYRNALHMLSTVCTEDYVTPYISVPP----------DTTTFPPD----STPCGLEDCPSGTEPEEISISPTFL-DLDVKPIMKLKQVSHTNAVITVQIPYPYKKMYILVLYNNSFFTDIQNLKRQKEDIELKNLKPHTDYTYCVASIRNSLRFNHTCLTLSTG-PKNGKERVASNATATHYIMTILGCLFSMVIVLGIVYYCLRKKRQQDEKHKKAG------SLKKNIIELKYGGELEGGTISRMSQKQMMAGESMTRMPYLPSGS-EMEQYKLQDISDTPKMAKGNYMEVRTGEHPDRRDCEMSMAG-NSQGSVAEISTIAKEVDKVNQIINNCIDALKSESTSFQGVKSGAVSTAEPQLVLISEQPQSKSGFLSPVYKDSYHHS-LQRHHASDAS--PKRPSTATGGSIRSPRPYRSE--GSYKS---ESKYIEKTSPTGETILTITPAAAILRAEAEKIRQYSEHRHSYPDAHQIEELEGP-----------ESRKTSILEPLTRPRARDLAYSQLSPQYHNLSYSSSPEYYCKPSHSIWERFKLHRKRHKDE-EYMAAGHALRKKVQFAKDEDLHDILDYWKGVSAQQKS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.: :* : :. .* * * .:.*******:*********************:**.**********:*:*::*::**** ************.********.**********:*:*******:****.**:**********.* ..:******* ********:* *...**:.*:**:.**:*:*** ********::**:.*.* :* :*: *:**. :** **.*. . . * *.:****. :. : ** :.. ** . **. ::* ** . : .*: : :.:* :*:**:::..*.* **:* *:::** * :*** :..*.: :*:*.*.** . *:*****.* . :.******:. . *.* :**************.**:*** ******::*:*:****** ****.******* *:*. :: ::* ::. *::**:****:. ::***** : .:*** :**.*:*****: :**.**:. .. :.*.*************:*********************.***.**.*** ***:** :* .**:* ***:: *. *****: :*: * *.**::.** ****.:*:* * :*: *:***** **. ::***:****::*****:* ***.*******.:* * * **:**********.***.*********.********* *:.* *****::* *:***:: *:********************************:**", "identical_positions": 475, "similar_positions": 196, "identity": "56.35%" }, { "cls_id": "homologset.agr.RGD:1308788", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LRG3-1", "uniprot_id": "A0ABK0LRG3_RAT", "id": "A0ABK0LRG3-1", "name": "Protein ripply3", "aln": "MRPEAAA-AREAQGRISHCPGDDPGRPPLPRGPESSIPAPWRPWMSPP-RDADLTRTERP--PWEDQQTLGSKGAFGFQHPVRLYLPISKRQEYLQSSGEKVLASFPVQATIHFYNDDSESSSEEEQEEEAQPNHLQCLEAEV------------RDSALEE--RAECGK-----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q924S9-1", "uniprot_id": "DSCR6_MOUSE", "id": "Q924S9-1", "name": "Protein ripply3", "aln": "MRPEAAG-VREARGRLCHCPGDDPGRLPLPRGPESSIPAPWRPWMSPPPGDAELTRTERPCESWGDQHTSGSKGAFGFQHPVRLYLPVSKRQEYLQSSGEKVLASFPVQATIHFYNDDSESGSEEEQEEEAQPNHLQCLEAEV------------RDSAQEE--RAE--------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P57055-1", "uniprot_id": "DSCR6_HUMAN", "id": "P57055-1", "name": "Protein ripply3", "aln": "MEPEAAAGARKARGRGCHCPGDAPWRPPPPRGPES--PAPWRPWIQTP-GDAELTRTGRPLEPRADQHTFGSKGAFGFQHPVRVYLPMSKRQEYLRSSGEQVLASFPVQATIDFYDDESTESASEAEEPEEGPPPLHLLPQEVGGRQENGPGGKGRDQGINQGQRSSGGGDHWGEGPLPQGVSSRGGKCSSSK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q2WG78-1", "uniprot_id": "DSCR6_DANRE", "id": "Q2WG78-1", "name": "Protein ripply3", "aln": "MLPVCVDADQALR-----CS------------------VLWRPWSLSP-TEARGHKTLAG----GVRSARPSGGVF--HHPVRLFLPRSRMQEYLSRLGSSVLASFPVQATLHFYNDE--DSSSEEEEDEEHANTRCRLWRP---------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * .. : : *. . **** .* :* :* : : * *.* :****::** *: **** *..**********:.**:*: ..:.* :* * . * ", "identical_positions": 42, "similar_positions": 28, "identity": "21.76%" }, { "cls_id": "homologset.agr.RGD:1308789", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ET80-1", "uniprot_id": "JPH1_MOUSE", "id": "Q9ET80-1", "name": "Junctophilin-1", "aln": "MTGGRFDFDDGGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSHGFEVVGVYTWPSGNTYQGYWAQGKRHGLGVETKGKWMYRGEWSHGFKGRYGVRQSLCTPARYEGTWSNGLQDGYGVETYGDGGTYQGQWAGGMRHGYGVRQSVPYGMATVIRSPLRTSLASLRSEQSNGSVLHEAAAAAADSPAGTRGGFVLNFHADTELG-KKKGGLFRRGSLLGSMKLRKSESKSSISSKRSSVRSDAAMSRISSSDANSTISFGDVDCDFCPVEDHVDATTTETYMGEWKNDKRNGFGISERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKNNILVRGIRKQLIPIRNTKTREKVDRAIEGAQRAAAMARTKVEIANSRTAHARAKADAADQAALAARQECDIARAVARELSPDFYQPGPDYIKQRCQEGGDIKENPEEKVLEKPPSPKESPHFYRKGTTPPRSPESSPKQSHSPQPSSPEPSKKQNPSPGARLSQDKQSLAEEQVTAFVNKPSMSKAPAKELGASV--SKYSGRHHVPNPSNGELHSQYHGYYVKLNTPQHPPEDREDDRGVSQSSSALVPRPSPNKWGPPKSVTKPVAKESKTEPKAKKSELAIPKNPASNDTCPSLEKEANSGPNSIMIVLVMLLNIGLAILFVHFLT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZQ55-1", "uniprot_id": "D3ZQ55_RAT", "id": "D3ZQ55-1", "name": "Junctophilin", "aln": "MTGGRFDFDDGGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSHGFEVVGGYTWPSGNTYQGYWAQGKRHGLGVETKGKWMYRGEWSHGFKGRYGVRQSLCTPARYEGTWSNGLQDGYGVETYGDGGTYQGQWAGGMRHGYGVRQSVPYGMATVIRSPLRTSLASLRSEQSNGSVLHEAAAAAADNPAGTRGGFVLNFHADTELG-KKKSGLFRRGSLLGSMKLRKSESKSSISSKRSSVRSDAAMSRISSSDANSTISFGDVDCDFCPVEDHVDATTTETYMGEWKNDKRNGFGISERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKNNILVRGIRKQLIPIRNTKTREKVDRAIEGAQRAAAMARTKVEIANSRTAHARAKADAADQAAVAARQECDIARAVARELSPDFYQPGPDYIKQRFQEGVDIKENPEEKVPEKPPSPKESPHFYRKGTTPPRSPEASPKQSHSPQPSSPKSMKKQNPSSGARLSHDKRNTAEEQVVAIVNKPLMSKAPSKELGATV--SKYSGRHYVPNPSNGELHSQYHGYYVKLNTPQHPPEDREDDSGVGQSSSALVPRPSPNKWSPPKSVTKPVAKESKTEPKAKKSELAIPKNTASNDTCPPLEKEANSGPNSIMIVLVMLLNIGLAILFVHFLT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9HDC5-1", "uniprot_id": "JPH1_HUMAN", "id": "Q9HDC5-1", "name": "Junctophilin-1", "aln": "MTGGRFDFDDGGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSHGFEVVGGYTWPSGNTYQGYWAQGKRHGLGVETKGKWMYRGEWSHGFKGRYGVRQSLCTPARYEGTWSNGLQDGYGVETYGDGGTYQGQWAGGMRHGYGVRQSVPYGMATVIRSPLRTSLASLRSEQSNGSVLHD-AAAAADSPAGTRGGFVLNFHADAELAGKKKGGLFRRGSLLGSMKLRKSESKSSISSKRSSVRSDAAMSRISSSDANSTISFGDVDCDFCPVEDHVDATTTETYMGEWKNDKRNGFGVSERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKNNILVRGIRKQLIPIRHTKTREKVDRAIEGAQRAAAMARTKVEIANSRTAHARAKADAADQAALAARQECDIARAVARELSPDFYQPGPDYVKQRFQEGVDAKENPEEKVPEKPPTPKESPHFYRKGTTPPRSPEASPKHSHSP-ASSPKPLKKQNPSSGARLNQDKRSVADEQVTAIVNKPLMSKAPTKEAGAVVPQSKYSGRHHIPNPSNGELHSQYHGYYVKLNAPQHPPVDVEDGDGSSQSSSALVHKPSANKWSPSKSVTKPVAKESKAEPKAKKSELAIPKNPASNDSCPALEKEANSGPNSIMIVLVMLLNIGLAILFVHFLT", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "************************************************** ******************************************************************************************************************************: ******.***************:**. ***.*************************************************************************************:*****************************************************:**********************************************:***************************:*** *** * ******** ****:*******************:***:**** .***:. ******.****.:**:. *:***.*:**** *****:** ** * *******::********************:***** * **. * .******* :**.***.*.************:**************.****:**.*********************************", "identical_positions": 606, "similar_positions": 37, "identity": "91.4%" }, { "cls_id": "homologset.agr.RGD:1308790", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "O35744-1", "uniprot_id": "CHIL3_MOUSE", "id": "O35744-1", "name": "Chitinase-like protein 3", "aln": "-------------------MAKLILVTGLAILLNVQLG--------------------------------SSYQLMCYYTSWAKDRPIEGSFKPGNIDPCLCTHLIYAFAGMQNN-----EITYTHEQD----------------------------LRDYEALNGLKDKNTE--LKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNFDGLNLDWQYPGS--RGSPPK-DKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYKIPELSQSLDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIG----KSADLNVDSIISYWKDHGAASEKLIVGFPAYGHTFILSDPSKTGIG-----APTISTGPPGKYTDESGLLAYYEVCTFLN---EGATEVWDAPQEVPYAYQGN-------EWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMDDFSGSFCHQR-------------------------------------------HFPLTSTLKGDLNIHSASCKGPY--------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q91Z98-1", "uniprot_id": "CHIL4_MOUSE", "id": "Q91Z98-1", "name": "Chitinase-like protein 4", "aln": "-------------------MAKLILVTGLAILLNVQLG--------------------------------SSYQLMCYYTSWAKDRPTEGSFKPGNIDPCLCTHLIYAFAGMKNN-----EITYLSEQD----------------------------LRDYEALNGLKDRNTE--LKTLLAIGGWKFGPAPFSSMVSTPQNRQTFIKSVIRFLRQYNFDGLNLDWQYPGS--RGSPPK-DKHLFSVLVQEMRKAFEEESTLNHIPRLLLTSTGAGFIDVIKSGYKIPELSQSLDYIQVMTYDLHDPKNGYTGENSPLYKSPYDIG----KSADLNVDSIITYWKDHGAASEKLIVGFPAYGHTFILSDPSKNGIG-----DPTVSAGPPGKYTNEQGLLAYFEICTFLN---EGATEIFDATQEVPYAYLGN-------EWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMDDFSGSFCHQG-------------------------------------------RFPLTTTLKRDLNVHSASCKASYRGEL----------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1M559-1", "uniprot_id": "F1M559_RAT", "id": "F1M559-1", "name": "", "aln": "-------------------MAKLILATGLAILLYAHLG--------------------------------SSYQLMCYYTSWAKDRPTVGSFKIGNIDPCLCTHLIYAFAGMRNN-----EIINTSEQD----------------------------LIDYEAINYLKDRNTE--LKTLLAIGGWKFGSAPFSAMVSTPQNRQTFIKSVIKFLRQYKFDGLNLDWQYPGS--RGSPPK-DKHLFSVLVQEMRKAFEKESTEQEIPRLLLTATVAGVIDTIQSGYKIPELSQSLDYFQVMTYNLHDFQNGYTRENSPLYQSPSDTG----IYAYLNVDAIISYWKDNGAAREKLIVGFPAYGHNFILSDPSNTGIN-----APIVSTGPPGKFTGEAGLWAYYEICTFLN---DGATDLWDGPQEVPYAVQGN-------VWVGYDNVKSFKIKAQWLKDNKLGGAMVWPLDMDDFTGSFCQQG-------------------------------------------RFPLTSTLKHYLGVQSTNCMA-YKEEL----------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BZP6-1", "uniprot_id": "CHIA_HUMAN", "id": "Q9BZP6-1", "name": "Acidic mammalian chitinase", "aln": "-------------------MTKLILLTGLVLILNLQLG--------------------------------SAYQLTCYFTNWAQYRPGLGRFMPDNIDPCLCTHLIYAFAGRQNN-----EITTIEWND----------------------------VTLYQAFNGLKNKNSQ--LKTLLAIGGWNFGTAPFTAMVSTPENRQTFITSVIKFLRQYEFDGLDFDWEYPGS--RGSPPQ-DKHLFTVLVQEMREAFEQEAKQINKPRLMVTAAVAAGISNIQSGYEIPQLSQYLDYIHVMTYDLHGSWEGYTGENSPLYKYPTDTG----SNAYLNVDYVMNYWKDNGAPAEKLIVGFPTYGHNFILSNPSNTGIG-----APTSGAGPAGPYAKESGIWAYYEICTFLK---NGATQGWDAPQEVPYAYQGN-------VWVGYDNIKSFDIKAQWLKHNKFGGAMVWAIDLDDFTGTFCNQG-------------------------------------------KFPLISTLKKALGLQSASCTAPAQPIEPITAAPSGSGNGSGSSSSGGSSGGSGFCAVRANG-----------------------------------------LYPVANNRNAFWHCVNGVTYQQNCQAGLVFDTSCDCCNWA---------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VFR3-1", "uniprot_id": "Q9VFR3_DROME", "id": "Q9VFR3-1", "name": "chitinase", "aln": "-------------------MVRYIPLLLLGVLCSWPAATVAS---------------------------DQASRIVCYFSNWAVYRTGIGRYGLEDVPADLCTHIIYSFIGVNDKSWDVLVIDPELDVD----------------------------QGGFSKFTQLKKSNPN--VKLEIAVGGWAEGGSKYSQMVAVRDRRQSFIRSVVRFMKQYNFDGFDLDWEYPGATDRGGNYG-DKDKFLYFVEELRRAFDREGRGWEITMAVPVAKFR-----LNEGYHVPELCEALDAIHAMTYDLRGNWAGFADVHSPLYKRKHDQY----AYEKLNVNDGLALWEEMGCPANKLVVGVPFYGRTFTLSNSNKNYNMG-TYINKEAGGGAPGPYTNASGFLAYYEICTEVMDKSKGWTVEWDDAGMVPYTYKDT-------QWVGYENEASIQIKMDFIKQRGYAGAMTWAIDMDDFHGMCGRKNGLTQILYDNMKNYRVPEPTRQTTPRPEWAKPPATPPNPDEGAVVAPTTSTTKRPKPKPKPTSSPLSPTSAPGPVPTVGSSTPKPTTKKPKKPKKTTTTTTTTPAPEKSTEEPEEVVYPVDPVEPTDPEQPMGPQFDPNEIDCTNRDFVPHPNCRKYFRCVHGKPVEFECKEGTAFHTVLNVCDWIENSDRYYCSRMKNKEKGNEAH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W2M6-1", "uniprot_id": "Q9W2M6_DROME", "id": "Q9W2M6-1", "name": "chitinase", "aln": "-----------------MKLVSIWALAALCLCLGQVAS--------------------------------SEKLLNCYWGTWANYRPGDGKFTPSDIDPSLCTHISYTFFGISDAG-EFKSLDTWLDMDD--------------------------GLGFISQTIALKQRNPN--LKILAVVGGWNEGSTKYSAMAADPAKRATFVSTSLAFIQQYSFDGLDLDWEYPGQ--RGGSEA-DRENFVTLLREIKETYDQYG--LELGIAVGASEKS-----ASISYDIPAISQHLTFINVMTYDFHMALDGYLGLNAPLPEVAESID----------------YWLSHGAPAEKLILGIGFYGHSYQMSDSSQNWPG-----AACIGPGTAGVYTRENGFLGYHEICLNN------WQTVFDQENGAPYAFQGD-------QWIGYDNPESIQLKMQLVESRNLGGAMMWSIETDDFRGLCG-ES--------------------------------------------YPLLKTMNRALGREVSGGSGGGGGGGGEGSVTPAPTAAPTSSPTPAPTPGGGSGGNECAQDG---------------------------------------FFVLESDCNKFYQCVGGVRYDFQCGAGLCFNTITLNCDWP---------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W2M5-1", "uniprot_id": "Q9W2M5_DROME", "id": "Q9W2M5-1", "name": "", "aln": "-------------------MGKLLALLAV-LCLSQVIG--------------------------------AERIVNCYWGTWANYRSGNGKFDVSNIDAGLCTHLSYSFFGINDNG-EIQSLDTWLDYD----------------------------LGFINQAISLKNQNSN--LKVLAVVGGWNEGSTKYSSMSGDWYKRQNFINSALNLLRNHGFDGLDLDWEYPNQ--RGGNWN-DRANFVTLLREIKEAFAPYG--YELGIAVGAGESL-----ASASYEIANIAQQVDFINVMTYDFAMASDGQTGFNAPQWAVENAIN----------------FWLSQGAPANKLVLGVGTYGRSFQLSDSSQNWPG-----APCRGEGSAGSYTGSTGYLGYNEICQNN------WHTVFDYDNAAPYAYSGD-------QWVSFDNVLSVQYKMDFALSKGLAGAMIWSLETDDYRGQCG-ET--------------------------------------------YPLLKTINRKLRW-----------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W2M7-1", "uniprot_id": "Q9W2M7_DROME", "id": "Q9W2M7-1", "name": "chitinase", "aln": "-------------MWSVSGLVKLLLGVILMAASSSAQGN-------------------------------SSKNVVCYQGTWSVYRPGLGKFGMEDIDPFLCTHLIYAFLGIEETG-QLRVIDAYLDLEE------------------------NSGRGNIKSFNALKLKNPV--LKTLVAVGGWNEGSKRFSLVARDPSKREKFVDDVVRFLQRHGFDGLDLDWEYPGQ--RHSLDNEDRSNYITFLKELKEGLEPFG--FILSAAVGSAQFS-----AEISYDIPAMVPYLDLINVMAYDLHGPWDQVVGINAPLYAAEKDASDSSGRQQQLNVDAVVKYWLKAGAPAEKLILGVPFYGRSFTLATAEGNQPG-----APHIGKGIAGNYSREPGVLGYNELCEMME--REEWTQKWEATQQVPYAYRQR-------QWVGYEDPRSLALKAQYVMDNHLGGIMIWSLESDDFRGTCGQQP--------------------------------------------YPLLHEINRVLFG--------------------GNTPSGLTTESNRESPSEGFSCPADAPAG---------------------------------------YIRDPDNCSKFYYCSGGKTHNFDCPSGLNFDLDTKSCNYSGSVKC----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W092-1", "uniprot_id": "CHIT2_DROME", "id": "Q9W092-1", "name": "Probable chitinase 2", "aln": "-----MTLRSRLSGEAPQLWLLLLLASTASSLWASVAARTGP---------------------------LHDKVVVCYVSTWAVYRPEQGAYAIENFDPNLCTHVVYAFAGLDITQAAIKSLDPWQDLKE------------------------EYGKGGYEKMTGLKRSHPH--LKVSLAIGGWNEGSANYSTLVANNLLRGRFVKQVSSFIRKYNFDGLDLDWEYPTQ--RKGKPA-DRENFVLLTKELREEFDEHG--LLLTSAIGASKKV-----IDEAYDVRQISRYLDYLHIMCYDYHGSWDRRVGYNAPLTAPADDPLS---------VKFSIDYLLKLGAPPEKLVMGLPFYGRTFKTLASG--FLN-----DVSEGVGFKGPYTREDGFLGYNEICQTLSNQTSGWTREWDPQTSQVLAKSERNVFTQEINVVTYDSSRSIANKVLFAMSKRLAGVMVWSVDTDDFLGNCKLDED------------------------------------------TYEDFQKVTAAPKRSSQNYPLLRTINEATMLAVDELAVPEPQPDDSENEIPHGSIAD--------------------------------------------------------RKNAGASMVSLGLGVTAVFMLLHRLAQ-----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06350-1", "uniprot_id": "CHI2_YEAST", "id": "Q06350-1", "name": "Sporulation-specific chitinase 2", "aln": "MVGHSAQHRSKSSLVSHLLILLIFITIIIEMCLYNKIFKNQRSDDIRDNFNNGGHRVPSNVQNHGTHIRDEAFISGVYYSNWSPYKPR--FHFPHDINLKQVSHIYYAFFKINSRTGGIENTDSWSDLEMNLYKSLAIKNSELIKESSNNSVQNILPLGCIGELFYLKNTCSDKKFKVIMSIGGWSD-SENFKIIIKDDKLLQNFVDSSVETMFRLGFDGIDLDWEFPGN--NESEPR-GYLKLVRMLRLKLNSLESQIFGKRTEDHFQLSIAAPAFKDKLFYLPITEIDQYVDYWNMMTYDYYGSWSETTGYHSNLFSETELNG----------NFAMHYMIDRFGVNSRKLVLGMAAYGRSFHIKDNKFEPFNQNTVLINKIFKGVGKPTKEIDKADGKEGIWPYKNLPKIGTIEQYDPKYVSAYCFDEKNS-----IFISYDNTKSVKTKAEYVTHNNLGGGFWWESCGEAYANESR------------------------------------------------SLINAFNEGLHFNVSSKPSIFQDVRVKKYYLNKYGDGGFLSPYLKHLDSRKQ-------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .*: :. . :. :*: *:* . ** . .* :*** :. : *: : . ***:::**::* . . . : . . . . : : : : * *: :: * .**::*. **:.: * . : :: : ::. *. * . .* . * : : . . ", "identical_positions": 31, "similar_positions": 63, "identity": "4.5%" }, { "cls_id": "homologset.agr.RGD:1308791", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q920F6-1", "uniprot_id": "SMC1B_MOUSE", "id": "Q920F6-1", "name": "Structural maintenance of chromosomes protein 1B", "aln": "-----------------------MGHLELLLVENFKSWRGRQVIGP-FKRFTCIIGPNGSGKSNVMDALSFVMGEKTTNLRVKNIQELIHG-----------AHTGKPVSSSASVTIIYIEDSGEEKTFTRIIRG--GCSEYHFGDKPVSRSVYVAQLENIGIIVKAQNCLVFQGTVESISMKKPKERTQFFEEISTSGEFIGEYEAKKKKLQKAEEDAQFHFNVKKNVAAERKHAKIEKEEAEHYQNLLEELKINKIQLMLFQLYYNEEKINVLNTELEQMDGNLSVVKDTLSHHENIFKAKKKDYGMLTRQLQQTAKELKSVEAILNQKRPQYIKAKENTSHHLKKLDLSKKLITDNEKQCSKQEDGIRALVAELADLDRAWKSFEKQMEEKILQKGRDIELENSQLDRYKLLKEQVRRKVGIMTQQLEKLQWEQKAEKERLAFEKRRHGDTQGN--LKQIKEQIEEHKKRIEKLEEYTKTCMDCLEDKKQQEEALKKEIENTKSRMSEVNEELSLIRNELQNAGIDNHEGKRQQKRAEVLEHLKRLYPDSVFGRLLDLCHPIHKKYQLAVTKLFGRYMVAIVVASEKIAKDCIRFLKAERAEPETFLALDYLDIKPINERLREIKG---CKMMIDVIKT--QFPQLKKVIQFVCGNGLVCETVEEARHIAFGGP-ERRKAVALDGTLFLKSGVISGGSSDLKHKALCWDEKELHNLRDKRSQLVQELKELMKTLR-KETDLKQIQTLVQGTNTRLKYSQNELEMIKKKHLATFYREQSQLQSELLNIDSQCTMLSEGINKQQQKIEEFQDKIDEVEDDIFQDFCEEIGVENIREFENKHVKQQQENDQKRLEFEKQKTRLNIQLEYSRNQLKKKLNNIDTLKTTIQKGKEDIDNLKKTEEECLKIVEELMVKQEQIKEVLATQSSNIEKIHIQIEEERKKVLAVDREVGKLQKEVVIIQGSLEQKLLEKHNLLLDCKVQDIDISLVLGSLEDIIEMEL-TETESTQATADIYEKEASIQIDYSPLREDLKALQSDKEVEAHLTLLLQQVASQENTLLKTTAPNLRAQENLKTVRDKFQESADVFEASRKEARICRQEFEQVKRRRYDAFSQCFEHISVSIDQIYKKLCRN-------NSAQAFLSPENPEEPYLDGISYNCVAPGKRFMPMDNLSGGEKCVAALALLFAVHSFRPAPFFVLDEVDAALDNTNIGKVSSYIKEQSQEQFQMIIISLKEEFYSKADALIGVYPEHNECMFSHVLTLDLSKYPDTEDQEGSRSHRKPRVPRVSMSPKSPQSR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZE73-1", "uniprot_id": "D3ZE73_RAT", "id": "D3ZE73-1", "name": "Structural maintenance of chromosomes protein", "aln": "-----------------------MGHLELLLVENFKSWRGRQVIGP-FKRFTCIIGPNGSGKSNVMDALSFVMGEKTTNLRVKNIQELIHG-----------AHIGKPVSSSASVTIIYVEDSGEEKTFTRIIRGRGGCSEFHFGDKPVSRSVYVAQLENIGIIVKAQNCLVFQGTVESISMKKPKERTQFFEEISTSGEFIGEYEAKKKKLQKAEEDAQFHFNRKKNVAAERKHAKIEKEEAEHYQSLLEELKTNKIQLMLFQLYYNEEKINVLNTELEHMDRNLSVVKDTLSHHENIIKAKKKDYGMLTRQLQQTAKELKSVEAVLNQKRPQYIKAKENTSHHLKKLDLSKKLITDNEKQCAKQEDGIRALVAELVDLDRAWRSFEKQMEEKILHKGRDIELENSQLDRYKELKEQVRRRVGIMTQQLEKLQWEQKAEKERLAFERRRHGDTQGN--LKQIKEQIEEHKKRIEKLEEYTKTCMDCLEDKKQQEEALIKEIDNTKSRMSEVNEELSLIRNELQNAGIDNHEGKRQRKRAEVLEHLKRLYPDSVFGRLLDLCHPIHKKYQLAVTKLFGRYMVAIVVASEKVAKDCIRFLKEERAEPETFLALDYLDIKPINERLREIKG---CKMMIDVIKT--QFPQLKKVIQFVCGNGLVCETVEEARHIAFGGP-ERRKAVALDGTLFLKSGVISGGSSDLKHKALCWDEKELHSLRDKRNQLVQELKELMKTLR-KETDLKQIQALVQGTNTRLKYSQNELEMIKKKHLATFYREQSQLQSELLNIDSQCTMLSEGINKQQQKIEEFQDKIDKVEDDIFQDFCEEIGVENIREFENKHVKQQQENDQKRLEFEKQKTRLNIQLEYSRNQLKKKLNKIDTLKTTIQKGREDIDNLKKTEEECLKIVEELMVKQEQVKEVLATQSSNIEKIHIQIEEERKKFLAVDREVGKLQKEVVIIQGSLEQKQLEKHNLLLDCKVQDIDISLMLGSLEDIIEVEL-TETESTQATADIYEKEASIQIDYSPLREDWKALQSDKEVEAHLTLLLQQVASQENTLLKTAAPNLRAQENLKAVRDKFQESADAFEASRKEARICRQEFEQVKRRRYDAFSQCFEHISVSIDQIYKKLCRN-------NSAQAFLSPENPEEPYLDGISYNCVAPGKRFMPMDNLSGGEKCVAALALLFAVHSFRPAPFFVLDEVDAALDNTNIGKVSGYIKEQSQEQFQMIIISLKEEFYSRADALIGVYPEHDECMFSHVLTLDLSKYPDTEDQEGSRSHRKPRA-RVSQSPQSPQSR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NDV3-3", "uniprot_id": "SMC1B_HUMAN", "id": "Q8NDV3-3", "name": "Structural maintenance of chromosomes protein 1B", "aln": "-----------------------MAHLELLLVENFKSWRGRQVIGP-FRRFTCIIGPNGSGKSNVMDALSFVMGEKIANLRVKNIQELIHG-----------AHIGKPISSSASVKIIYVEESGEEKTFARIIRG--GCSEFRFNDNLVSRSVYIAELEKIGIIVKAQNCLVFQGTVESISVKKPKERTQFFEEISTSGELIGEYEEKKRKLQKAEEDAQFNFNKKKNIAAERRQAKLEKEEAERYQSLLEELKMNKIQLQLFQLYHNEKKIHLLNTKLEHVNRDLSVKRESLSHHENIVKARKKEHGMLTRQLQQTEKELKSVETLLNQKRPQYIKAKENTSHHLKKLDVAKKSIKDSEKQCSKQEDDIKALETELADLDAAWRSFEKQIEEEILHKKRDIELEASQLDRYKELKEQVRKKVATMTQQLEKLQWEQKTDEERLAFEKRRHGEVQGN--LKQIKEQIEDHKKRIEKLEEYTKTCMDCLKEKKQQEETLVDEIEKTKSRMSEVNEELNLIRSELQNAGIDTHEGKRQQKRAEVLEHLKRLYPDSVFGRLFDLCHPIHKKYQLAVTKVFGRFITAIVVASEKVAKDCIRFLKEERAEPETFLALDYLDIKPINERLRELKG---CKMVIDVIKT--QFPQLKKVIQFVCGNGLVCETMEEARHIALSGP-ERQKTVALDGTLFLKSGVISGGSSDLKYKARCWDEKELKNLRDRRSQKIQELKGLMKTLR-KETDLKQIQTLIQGTQTRLKYSQNELEMIKKKHLVAFYQEQSQLQSELLNIESQCIMLSEGIKERQRRIKEFQEKIDKVEDDIFQHFCEEIGVENIREFENKHVKRQQEIDQKRLEFEKQKTRLNVQLEYSRSHLKKKLNKINTLKETIQKGSEDIDHLKKAEENCLQTVNELMAKQQQLKDIRVTQNSSAEKVQTQIEEERKKFLAVDREVGKLQKEVVSIQTSLEQKRLEKHNLLLDCKVQDIEIILLSGSLDDIIEVEMGTEAESTQATIDIYEKEEAFEIDYSSLKEDLKALQSDQEIEAHLRLLLQQVASQEDILLKTAAPNLRALENLKTVRDKFQESTDAFEASRKEARLCRQEFEQVKKRRYDLFTQCFEHVSISIDQIYKKLCRN-------NSAQAFLSPENPEEPYLEGISYNCVAPGKRFMPMDNLSGGEKCVAALALLFAVHSFRPAPFFVLDEVDAALDNTNIGKVSSYIKEQTQDQFQMIVISLKEEFYSRADALIGIYPEYDDCMFSRVLTLDLSQYPDTEGQESSKRHGESR--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32THU2-1", "uniprot_id": "A0AB32THU2_DANRE", "id": "A0AB32THU2-1", "name": "Structural maintenance of chromosomes protein", "aln": "-----------------------MGFLKQLDVENFKSWRGKQTIGP-FKRFNCIIGTNGSGKSNVMDALGFVMGERAANLRVKHTRDLIHG-----------AHIGNPVSTFASVTMIYCGDNDEEMTFSRRISG--ESSEYLVNGKHVTLAKYTGELQKIGIVVKAKNCLVYQGAVESIAMMNAKERTKMFERISGSGDLNIEYDTKLAVLQKAKEDTQFHFNRKKAATAEKKQVFKDKTEAQRYQSLVDDLRECKLQLTLFQLFHNEKSIDAQSASLGDMQAAAAQQKISLDAWEQTVKTQKKEHGRLNRELQQLEKEIRSQEQILNQQRPQYIKAKVNTSHHEQKVQEAHRSLQKYQNLQAKKVQELEELKRELTELERAWKTSERQMEEEEARRGAGVQLQESQLERYKELKELARRNGAILNQSAEKLHWEVKADREKLQFDLRRKSEIQGN--IKHSQTHLEDISRRAEKLEEYVNTTTQTLEEQRQQEEQLSEELAKGLLRMEEVNVELAQVLTKLQNARLDSQENRRQQKRDEVLESLRRLYPDTVYGRLVELCQPIHKKYQLAVTKVFGKNMNAIVVTSAYVAHDCIRYLKEERAEPETFLPIDYIDVPILNERLREVQG---AKMVVDVVQCSQNAPQLKRVIQYVCGNSLVCETLKDARRIAFDGP-ERLQTVALDGTLFRKSGVISGGSSDLSKKARRWEEKDMNKLKEEKDKLSSEMRALMKLKR-KEVDLKQIRAQSQGNQTRLKYANTELDSIRKKSIPAAQIEISKLRSELSNLEAQIEIQTGSMELKDSEMKAVKDKIHQMEDLVFADFCAEIGVANIREYEQDYLRLQQELEKKRLQFESQQTRLSTQLEYEQAQLGKLVKLMKKIEETIEKEKNIIISLKEGEDNILIAVEQTQSNLLKLNNQHSEKTHLVNNAKTELDKALTGLQERNKVLMKLQKQTISTDAALEHLRLTKHNLLLTCKIDGLPLTLISGALDDISEIQLDSESQS-VSTLDIFEREAQMVFDFSALDNSLKMLTEESEVEAMLEKLKEGVSSLESMIMMSRAPNLKALDKIREVKDSYREVLDAFDISTITTKKRNQEFEQVKAKRFHLFSQCFEHVSVVIDQIYKKLCRN-------ASAQAILSAENPNEPYLDGINYNCVAPGKRFMAMDNLSGGEKAIAALALVFAIHSFRPAPFFVLDEVDAALDNTNIGKVTGFFRMMSRESCQIIVISLKEEFYSRADALLGVYSMFDECMFSRLLTLDLTPYPLNDENATDREKDK----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VCD8-1", "uniprot_id": "Q9VCD8_DROME", "id": "Q9VCD8-1", "name": "Structural maintenance of chromosomes protein", "aln": "MTEEDDDVAQRVATAPVRKPDDETAFLEYIEMENFKSYRGHIVVGP-LKQFNAVIGPNGSGKSNFMDAISFVMGEKTSSLRVKRLNDLIHG-----------SSIGKPVSRSCYVTAKFVLNEERHMDFQRAVIG--GSSEYRINGESVSSSTYLNKLEKIGINVKAKNFLVFQGAVENIAMKTPKERTALFEEISGSGLLKDDYNRLKQEMIVAEEETQFTYQKKKGIAAERKEAKHEKMEADRYTRLQNEYNEKQVEYQLFRLFHVERDIRKFTSDLEVRQQEVKAVEQRKEAADEILREKKKDAGKITRDLAKIDQEIREFETQMNKRRPLYIKAKEKVTHCKKKLISLQKTLETAREADNAHQSDIRKLEKQLADVEALKKRFEDEIENESQRRGKSVNMEEGLVQEYDRLKQEAEATATQYRSELDSVNREQKSEQDTLDGETNRRASVEES--FKKLTLQREEAVKRRDKLMDHIKSSQAALEEQNRIKDELRRDVGTSKEKIAEKQRELEDVRDQLGDAKSDKHEDARRKKKQEVVELFKKQVPG-VYDRMINMCQPTHKRYNVAVTKVLGKFMEAIIVDTEKTARHCIQILKEQMLEVETFLPLDYLQVKPLKERLRNISDPRNVRLVFDVLKF--EPQEIERAVLFATGNALVCETPEDAMKVAYEIDRSRFDALALDGTFYQKSGLISGGSHDLARKAKRWDEKHMAQLKMQKERLQEELKELVKKSR-KQSELATVESQIKGLENRLKYSMVDLESS-KKSISQYDNQLQQVQSQLDEFGPKILEIERRMQNREEHIQEIKENMNNVEDKVYASFCRRLGVKNIRQYEERELVMQQERARKRAEFEQQIDSINSQLDFEKQ--KDTKKNVERWERSVQDEEDALEGLKLAEARYLKEIDEDKEKMEKFKQDKQAKKQAVDDMEEDISKARKDVANLAKEIHNVGSHLSAVESKIEAKKNERQNILLQAKTDCIVVPLLRGSLDDAVRQSDPDVPSTSAAMENIIE------VDYSSLPREYTKLKDDSAFKKTHEMLQKDLQSKLDVLERIQTPNMKALQKLDAVTEKVQSTNEEFENARKKAKRAKAAFERVKNERSSRFVACCQHISDAIDGIYKKLARN-------EAAQAYIGPDNPEEPYLDGINYNCVAPGKRFQPMNNLSGGEKTIAALALLFSTHSFHPAPFFVLDEIDAALDNTNIGKVASYIRDHTTN-LQTIVISLKEEFYGHADALVGITPGEGDCLVSNVYIMDLTTFEDT---------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32908-1", "uniprot_id": "SMC1_YEAST", "id": "P32908-1", "name": "Structural maintenance of chromosomes protein 1", "aln": "-----------------------MGRLVGLELSNFKSYRGVTKVGFGESNFTSIIGPNGSGKSNMMDAISFVLGVRSNHLRSNILKDLIYRGVLNDENSDDYDNEGAASSNPQSAYVKAFYQKGNKLVELMRIISRNGDTSYKIDGKTVSYKDYSIFLENENILIKAKNFLVFQGDVEQIAAQSPVELSRMFEEVSGSIQYKKEYEELKEKIEKLSKSATESIKNRRRIHGELKTYKEGINKNEEYRKQLDKKNELQKFQALWQLYHLEQQKEELTDKLSALNSEISSLKGKINNEMKSLQRSKSSFVKESAVISKQKSKLDYIFKDKEKLVSDLRLIKVPQQAAGKRISHIEKRIESLQKDLQRQKTYVERFETQLKVVTRSKEAFEEEIKQS-ARNYDKFKLNENDLKTYNCLHEKYLTEGGSILEEKIAVLNNDKREIQEELERFNKRADISKRRITEELSITGEKLDTQLNDLRVSLNEKNALHTERLHELKKLQSDIESANNQEYDLNFKLRETLVKIDDLSANQRETMKERKLRENIAMLKRFFPG-VKGLVHDLCHPKKEKYGLAVSTILGKNFDSVIVENLTVAQECIAFLKKQRAGTASFIPLDTIETELPTLSLPDSQD---YILSINAIDY---EPEYEKAMQYVCGDSIICNTLNIAKDLKWKKG-IRGKLVTIEGALIHKAGLMTGGIS--GDANNRWDKEEYQSLMSLKDKLLIQIDELSNGQRSNSIRAREVENSVSLLNSDIANLRTQVTQQKRSLDENRLEIKYHNDLIEKEIQPKITELKKKLDDLENTKDNLVKEKEALQNNIFKEFTSKIGFT-IKEYENHSGELMRQQSKELQQLQKQILTVENKLQFETDRLSTTQRRYEKAQKDLENAQVEMKSLEEQEYAIEMKIGSIESKLEEHKNHLDELQKKFVTKQSELNSSEDILEDMNSNLQVLKRERDGIKEDIEKFDLERVTALKNCKISNINIPISSETTIDDLPISSTDNEAITISNS--------IDINYKGLPKKYKENNTDS-----ARKELEQKIHEVEEILNELQPNARALERYDEAEGRFEVINNETEQLKAEEKKILNQFLKIKKKRKELFEKTFDYVSDHLDAIYRELTKNPNSNVELAGGNASLTIEDEDEPFNAGIKYHATPPLKRFKDMEYLSGGEKTVAALALLFAINSYQPSPFFVLDEVDAALDITNVQRIAAYIRRHRNPDLQFIVISLKNTMFEKSDALVGVYRQQ-QENSSKIITLDLSNYAE----------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * : :.****:** :* .*..:**.*******.***:.**:* : ** : .:**: * . * . :. .. : . :.: ...: *: * *:: .* :**:* **:** **.*: .. * : :**.:* * :*: : .:.: : :: .* : : :.* :. . : *::*:: *.. . .* : . . : .: *.. . : : .:: :: . * ::: .: : .: : :. : :* : . * ::::. :. .::: . :. *. *:: .. : : * : : .::.. . :. *. : :.* : :: : . * :: . : : : :* :: : : :* :.:* * : ::: *. * . : ::*:* :::* :**:.::*: : :::* . *:.** ** : :*:.:* :: . * : .. : .:.:. : ::.: :. *:.::*:* : * : * . ::::*:: *:*:::** *:::. .* :.: :: * : * :. :. . :. : :: :. : :: .: :. : . . .: . ::: :: * .:*. *:::*: :: :: :::.* :. :*::. . . : ::. : *: * : . : : :: . ::.. . : : . . :* : . * .* . : : : : * . : .::. * .. . :. : . : ** :* :. . . : : : * ::* .* * :::* :* **::* :* ..:* : :: :**: **.*:...* *** *: ****** :*****:*: :*::*:*******:***** **: :::.::: * *:****: :: ::***:*: : *.: :**: : ", "identical_positions": 179, "similar_positions": 403, "identity": "13.75%" }, { "cls_id": "homologset.agr.RGD:1308792", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LJ11-1", "uniprot_id": "A0ABK0LJ11_RAT", "id": "A0ABK0LJ11-1", "name": "", "aln": "MRYIVEIKMESVQEILDHLYRKVLLGATLEDDLHGYIVYLNPDLSEQAVCTASSVARSDVRDVLDGMAGQHG-----VSILPEAQECSRRQLQTGRAWEVTLLQLTLIDMVLSRVLSAETESRAKAGYRELTEVLLQSIELDSKLIRVLQNSDKLLSYLAAKCLASLLYFQLREK-----KMLSNSWVTFCQKHLSDSSEGGEAVHCLCVLAAVMKEIFKDAHSQRAESLKQLLTPFDNTFEAFYNS-----LFSQHFGNFKNPSNIISSLMCFLELLELLVASRIHLKLHLRSQRMLFLKP-HALDILAWPIPAFIKRKLVILIKKCLLCKVGEDFCRESVPTLMSPDHLLDSDMLALADALLHAIHLG---------------LWKALTVPGKPSCFGGDEVQPGCRLRAGPDHVTLRAASLITVKSLEIKFQNCTSATEMKADLQKF-LPEFLAFLKPQLQPSLQLHNPCEWLSRVFIEQDDDMLEAAKASLSIYLHLTREWDTSTSLTP--------------EKEAWIHSTHGHGYNPHCIFLFFLKNIAFDSTVLLDFLISSETCFLEY----FVKYLKLLQKDWGHFLSTCQFFAAMESQCGVSVHDPFPLPAHGTSTSYTAPHAP----VGENACPWIPWAADASSEPQSQ---PKETHPVPTNGPPSRTPQSLVDYDSSEPSDEEATDEPLANSKQTS------------LCQEMPGEIQDLPRTCKGKE-RSREPQARPLLSAEPNSPFSDDGGVAP--------------------------------------------------FLRTVRCLEELQRAIYRLQEKNLFPYNPAALLKLLKGVEAKCDNV----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3U1D0-1", "uniprot_id": "LINES_MOUSE", "id": "Q3U1D0-1", "name": "Protein Lines homolog 1", "aln": "MRYILDIKMEIVQEILDQLYRKVLLGTTLEDDVHGYIFYLNPDLSEQDGCPAFPVAQSNASGVLDGMAGQHGPSSHEVATLPGAQECPKRQLQMDRTREMKLLQLTVIDTMLSQVLSDETETHAKEGYRELTEVLLQSVELDSKLMRMLQNSDKLLSHMAAKCLASLLYFQLREKVRSQHKMLSNSWVTFCQKHLSESSESGEAVRCLWILTAVIKEILKDTHSQRAESLKQLLTPFDITFEVFYNS-----LFSQHFGDFQSPSNLASSLMCFLELLELLVASRIHLKLHFRSQRMLFLKP-HALDILAWPIPAFIKRKLVILVKKCLLCKVGEDLCREPAPSLMSPDHLLDSDMLTLADTLLHAVHVG---------------LWKALAVSGKPSCFGGDEVQPGCRLRTGPDHVTLRAASLITVKSLEIKSQNCTSAAEMKVALQTF-MSELLAFLKPHLQPSLQPHNPCEWLSRVFIEQDDDMLEAAKASLSIYLQLTREWDASASLTQ--------------EKEAWIRSTHGHGCNPHCVFLFFLKNVAFDSTVLLDFLISSETCFLEY----FVKYLKLLQKDWAHFLSICKFFAAVESQCGMLVHDPVPSPARGRSTSLTVPHAPAS-PVGENTCPWLPWASDASSESQSQVMMPKETLPVPANGPPSRTPQSLVDYDSSEASEEETTSEHLANSKQTS------------LCQERSEEIQGLPRTWEEQ----KEHSLEPLLSAESSSPFSAKGRVAADGTVW-----------------------------------------QVGLFLRTVKCLEELQGAIYRLQEKNLFPYNPAALLKLLKGVEAKCVNV----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NG48-1", "uniprot_id": "LINES_HUMAN", "id": "Q8NG48-1", "name": "Protein Lines homolog 1", "aln": "--------MKVFCEVLEELYKKVLLGATLENDSHDYIFYLNPAVSDQDCSTATSLEWANTC----GIQGRHQPISVGVAPIAVAPVCLKTNSQMSGSREVMLLQLTVIKVMTTRILSVKTEFHAKEQYRDVIKILLESAKVDSKLICMFQNSDKLLSHMAAQCLALLLYFQLREK-----ITLSNSWIAFCQKNLSEYSESNKAIYCLWTLTAIIKEIFKDSCSQKTEILKQFLTHFDTIFEVFYNS-----LFSQHFENCRDTSKIVNILMCFLDLLELLIASRIHLKLHFTCQRILFLKPSCMLEVITWPIQAFVKRKVIIFLKKCLLCKVGEDLCRGSVPALMPPDHHVAVDMLALANAVLQAVNSG---------------LLKTLSVYEKHSFFGGDEVQPECELITSPDHVILRAASLVIMKSLEIKFQNYSSASEVKVDLQRF-MSELLTFLKPHLQPSLQLHNPCKWLSRVFIEQDDDMLEAAKASLGIYLTLTRGCEATESLTQ--------------GKEMWDHHTHENGYNPHCIFLFFLKNIGFDSTVLLDFLISSETCFLEY----FVRYLKLLQKDWDNFFTICNNFDATESKYDISICGCVPSLVQDQSSNQTIPHRLTAPHSHRDVCARHSWASDAPSEPLKAVMSKGAHTMCASSLSSPRASQSLVDYDSSDDSDVESTEQCLANSKQTS------------LHQQATKEIQDAAGTSRDKKEFSLEPPSRPLVLKEFDTAFSFDCEVAPNDVVS-----------------------------------------EVGIFYRIVKCFQELQDAICRLQKKNLFPYNPTALLKLLKYIEVISNKTMNTL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V4Z9-1", "uniprot_id": "LINES_DROME", "id": "Q9V4Z9-1", "name": "Protein lines", "aln": "-MDTSSAAGSGAGTGDVCPCSTVATSTTSASNEQPQTKRQKIEQQIKVGSKALPPQPPHPPDILDLDANSNSHLCSSLSSSSSHSLSTPSTANNSPTTTPCSSRAASYAQLLHNILPQNGDTDLHSQPESAHDEVDRAAKLPNLLTLDTTNGNGSHASSRSNCLQATTATSIDDM-----LEFEQSLTRQCLCGVSERTLR-KPFQSHYSQDTNGQKRIAYLREWPTNKLLQFLSNLQLLFDIYLKQNAKGFICTRIMDVCDALIRNDHKLIDEIIVLAGYENSYVQFLAGRVLAAFLVIAKQELNDEWLQKIVDQLFNFEQLDQAAVQKIHFSLDIIKRIVEWKDMEIHPLDDDWMASANSTSAASSVVPLSTEASVSYMHFPVQEQPLATNYFALQFREDTEGERETGQEAPDNRDRHRRHFGEDMNVAYEPHPAPQSTTMPSGCHVVTLTDSESFDTTHLKCITIQKLEHKWPTLVKNMSELMAPTHQDAAEHCVLNFLQLWENIISVKANLSIDETRPYYAQLDKFELLLSHSLSCTVYKQMLCLFNEALCYGSTLALQDMLPEETCKLAHQIVCHVRGFRILESLPRRQPDNMVSLIGYNGKPMVYANGTITLAHAAQSGDSEEDGAPLDLIEMDKTLLQKMVLLVLKSIAVTVKEIRSDSSDSSIDSTDYDAFQDMMLIERSIRDVLSKLETFIKQTLEFHPECHFSKILIHLFDDQDDHLIEAMVCTLDVTSGISFRNNAFPELVAMLNPVYTFLEFLKMTSNSSDLLLDLLVSNETCFLLYLLRLLKYIRMNWTMFVHSCHTFGMGSAMLDEAMGVLIRLRLQISRLVSRQLYPYDISPVLRLLESCESLYEGNELS-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .* .:* .: : : . : . * . .. . : :: . . : . : : : : .:*. : : : .. . : .: :: . * *.: : ::** .: : :.:* * :*: : :.. . : :: : . :: * *:*: :: *: : :. : :: : . *: : :* * ::: :*.: : * : . : :.. *: : . * : * :: *:: * :.*:. * * .**: : : .: : : ..:: : : . :.: :* ..:*: : :* : * .: .*: * : : : *:. * : :: :* : : :.**: *: ::..*** * : .*: :::*:. . : . :.: : . .. * . .. * . . . . . : *.:: : * . . . : :: : : :: *: * . * : .. :: : : . : : .*: * ** .::*:**: :.:*:**: * ", "identical_positions": 66, "similar_positions": 221, "identity": "7.62%" }, { "cls_id": "homologset.agr.RGD:1308793", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q64060-1", "uniprot_id": "DDX4_RAT", "id": "Q64060-1", "name": "Probable ATP-dependent RNA helicase DDX4", "aln": "---------MGDEDWEA----------EILKPHVSSYVPVFEKDKYSSGANGDT-FNRTSASSSEMEDGPSGRDHFMRSGFSSGRNLGNRDIGESSKRETTSTTGGFGRGKGFGNRGFLNNKFE-EGDSSGFWKESTNDCEDTQT--RSRGFSKRGGYP------DGNDSE---ASGPFRRGGR---------------DSEYDQDQGSQRG-------GGLFGSRKPAASDSGSGDTFQ-------------SRSGNA--RGAYKG------LNEEVVTGSGKNSWKSEAE------------GGESSDIQGPKVTYIPPPPPEDEDSIFAH-YQTGINFDKYDTILVEVSGHDAPPAILTFEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIVLAGRDLMACAQTGSGKTAAFLLPILAHMMRDGITASRFKELQEPECIIVAPTRELINQIYLEARKFSFGTCVRAVVIYGGTQFGHSIRQIVQGCNILCATPGRLMDIIGKEKIGLKQVKYLVLDEADRMLDMGFGPEMKKLISCPGMPSKEQRQTLLFSATFPEEIQRLAGEFLKSNYLFVAVGQVGGACRDVQQSILQVGPVFKKRKLVEILRNIGDERPMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQALGDFRCGKCPVLVATSVAARGLDIENVQHVINFNLPSTIDEYVHRIGRTGRCGNTGRAISFFDTESDNHLAQPLVKVLSDAQQDVPAWLEEIAFSSYAPPSFSNSTRG-AVFASFDTRKNFQGKNTLNTAGISSA-QAPNPVDDESWD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61496-1", "uniprot_id": "DDX4_MOUSE", "id": "Q61496-1", "name": "ATP-dependent RNA helicase DDX4", "aln": "---------MGDEDWEA----------EILKPHVSSYVPVFEKDKYSSGANGDT-FNRTSASS---------------------------DIGESSKKENTSTTGGFGRGKGFGNRGFLNNKFE-EGDSSGFWKESNNDCEDNQT--RSRGFSKRGGCQ------DGNDSE---ASGPFRRGGRGSFRGCRGGFGLGRPNSESDQDQGTQRG-------GGLFGSRKPAASDSGNGDTYQ-------------SRSGSG--RGGYKG------LNEEVVTGSGKNSWKSETE------------GGESSDSQGPKVTYIPPPPPEDEDSIFAH-YQTGINFDKYDTILVEVSGHDAPPAILTFEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIVLAGRDLMACAQTGSGKTAAFLLPILAHMMRDGITASRFKELQEPECIIVAPTRELINQIYLEARKFSFGTCVRAVVIYGGTQFGHSVRQIVQGCNILCATPGRLMDIIGKEKIGLKQVKYLVLDEADRMLDMGFGPEMKKLISCPGMPSKEQRQTLLFSATFPEEIQRLAGDFLKSSYLFVAVGQVGGACRDVQQTILQVGQYSKREKLVEILRNIGDERTMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQALGDFRCGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAISFFDTDSDNHLAQPLVKVLSDAQQDVPAWLEEIAFSTYVPPSFSSSTRGGAVFASVDTRKNYQGKHTLNTAGISSS-QAPNPVDDESWD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NQI0-1", "uniprot_id": "DDX4_HUMAN", "id": "Q9NQI0-1", "name": "Probable ATP-dependent RNA helicase DDX4", "aln": "---------MGDEDWEA----------EIN-PHMSSYVPIFEKDRYS-GENGDN-FNRTPASSSEMDDGPSRRDHFMKSGFASGRNFGNRDAGECNKRDNTSTMGGFGVGKSFGNRGFSNSRFE-DGDSSGFWRESSNDCEDNPT--RNRGFSKRGGYR------DGNNSE---ASGPYRRGGRGSFRGCRGGFGLGSPNNDLDPDECMQRT-------GGLFGSRRPVLSGTGNGDTSQ-------------SRSGSGSERGGYKG------LNEEVITGSGKNSWKSEAE------------GGESSDTQGPKVTYIPPPPPEDEDSIFAH-YQTGINFDKYDTILVEVSGHDAPPAILTFEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILAHMMHDGITASRFKELQEPECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGTQLGHSIRQIVQGCNILCATPGRLMDIIGKEKIGLKQIKYLVLDEADRMLDMGFGPEMKKLISCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVGGACRDVQQTVLQVGQFSKREKLVEILRNIGDERTMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAISFFDLESDNHLAQPLVKVLTDAQQDVPAWLEEIAFSTYIP-GFSGSTRG-NVFASVDTRK---GKSTLNTAGFSSS-QAPNPVDDESWD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GIH0-1", "uniprot_id": "A0AC58GIH0_DANRE", "id": "A0AC58GIH0-1", "name": "RNA helicase", "aln": "MRFQIKRDQTTDSNGSANHSLDSFKKKNLFKTRIGRYIDFPAHEQNDDVIAGHLSFSREALHACPPATGSSEKKSHLKLPNMDDWEEDQSPVVSCSSGFGLGSNGSDGGFKSFYTGGAGNDKSNSEGTEGSSWKMTGDSFRGRGG--RGGSRGGRGGFSGFKSEIDENGSDGGWNGGESRGKGRGGFRGGFRS-GSRDENDENGNDDGWKGGESRGRGRGGFGGGFRGGFRDGGNEDTGRRGFGRENNENGNDEGEGRGRGRGGFRGGFRDGGGDESGKRGFGRGGFRGRNEEVFSKVTTADKLDQEGSENAGPKVVYVPPPPPEEESSIFSH-YATGINFDKYDDILVDVSGSNPPKAIMTFEEAGLCDSLSKNVSKSGYVKPTPVQKHGIPIISAGRDLMACAQTGSGKTAAFLLPILQRFMTDGVAASKFSEIQEPEAIIVAPTRELINQIYLEARKFAYGTCVRPVVVYGGINTGYTIREVLKGCNVLCATPGRLHDLIGRGKIGLSKVRYLVLDEADRMLDMGFEPEMRKLVASPGMPSKEERQTLMFSATYPEDIQRMAADFLKVDYIFLAVGVVGGACSDVEQTIVQVDQYSKRDQLLELLRATGNERTMVFVETKRSADFIATFLCQEKISTTSIHGDREQREREKALSDFRLGQCPVLVATSVAARGLDIEQVQHVVNFDMPSSIDEYVHRIGRTGRCGNTGRAVSFFNPESDTPLARSLVKVLSGAQQVVPKWLEEVAFSAHGTTGFNP--RG-KVFASTDSRKGGSFKSDEPPPSQTSAPSAAAAADDEEWE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P09052-1", "uniprot_id": "VASA1_DROME", "id": "P09052-1", "name": "ATP-dependent RNA helicase vasa", "aln": "---------MSDDWDDE----------PIVDTRGARGGDWSDDEDTAKSFSGEAEGDGVGGSG---------------------------GEGGGYQGGNRDVFGRIGGGRGGGAGGYRGGNRD-GGGFHGGRREGERDFRGGEGGFRGGQGGSRGGQG------GSRGGQ-----GGFR-GGEGGFRG-----------RLYENEDGDERR-------GRLDREERGGER-RGRLDREE---------------------RGGERG--------ERGDGGFARRRRNEDDIN---------NNNNIVEDVERKREFYIPPEPSNDAIEIFSSGIASGIHFSKYNNIPVKVTGSDVPQPIQHFTSADLRDIIIDNVNKSGYKIPTPIQKCSIPVISSGRDLMACAQTGSGKTAAFLLPILSKLLED----PHELELGRPQVVIVSPTRELAIQIFNEARKFAFESYLKIGIVYGGTSFRHQNECITRGCHVVIATPGRLLDFVDRTFITFEDTRFVVLDEADRMLDMGFSEDMRRIMTHVTMRP--EHQTLMFSATFPEEIQRMAGEFLKN-YVFVAIGIVGGACSDVKQTIYEVNKYAKRSKLIEILSEQADG-TIVFVETKRGADFLASFLSEKEFPTTSIHGDRLQSQREQALRDFKNGSMKVLIATSVASRGLDIKNIKHVINYDMPSKIDDYVHRIGRTGRVGNNGRATSFFDPEKDRAIAADLVKILEGSGQTVPDFLRTCGAG--GDGGYSN-----QNFGGVDVRG----------RGNYVG-DATNVEEEEQWD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. . : .: . .: *. . . . . * * :. * ... : * . : . .. *. . *** . ...: * * *. :: : * : : * * . **. :* * * .: . . .: : *:** *.:: .**: :**:*.**: * *.*:* : * .* * .*.* : : .*: *:** **:** .**:: :*********************** ::: * .: *: .*: :**:***** **: *****:: : :: ::*** . : . : :**::: ****** *::.: * :.. :::************* :*::::: * . ::***:****:**:***:*.:*** *:*:*:* ***** **:*:: :*. *: :*:*:* .: .:******: ***:*:**.::::.******** * :**:** **: *. **:*****:*****::::**:*:::**.**:********** **.*** ***: :.* :* ***:* .: * ** :*. . . .:. *.. * * . . .*. ::*.*:", "identical_positions": 233, "similar_positions": 190, "identity": "29.02%" }, { "cls_id": "homologset.agr.RGD:1308795", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "E9PT49-1", "uniprot_id": "E9PT49_RAT", "id": "E9PT49-1", "name": "", "aln": "MAEEQQQPPPQQLDAHQQLPLSAPNP-GVALPALVPGLPGTEASALQHKIKNSICKTVQSKVDCILQEVEKFTDLEKLYLYLQLPSGLSSAEKSDQNAMSSSRAQQMHAFSWIRNTLEEHPETSLPKQEVYDEYKSYCDNLGYHPLSAADFGKIMKNVFPNMKARRLGTRGKSKYCYSGLRKKAFVHMPTLPNLDFHKTGDGLEGVEPSGQLQNIDEEVISSACRLVCEWAQKVLSQPFDTVLELAHFLVKSHYIGTKSMAALTVMAAAPAGLKGISQPSAFIPTAESNSFQPQVKTLSSPIDAKQQLQRKIQKKQQEQKLQSPLPGESSAKKTEGTTANGVANLPNGNPAILSPQPIGIVVAAVPSPIPVQRTRQLVTSPSPMNSSDGKVLPLNVQVVTQHMQSVKQTPKTPQNVPASPGGDRSARHRYPQILPKPANTSALTIRSPTTVLFTSSPIKTAVVPASHMSSLNVVKMTTISLTPSNSNAPLKHSASVSNATGTTEDSRSIPQIKNGSVVSLQSPGSRASSTGGTSAVEVKMEPEGSSDEHPLQCQENAEGTKAPLATSSALWGQKSNTDGTVSKPSNEGVTEVKTTKVCDQRAKCKSRCNETLPGISAGNNQSTVTLSVATQNLPFTSTSSPSNGDSVNKDPKLCTKSPRKRLSATLQESQVPPVKKPIVEQLSAVTTEGQKPGTVKKDQKVPHSGKTESSTAGAQPPNKVSLSVSSHIVEDQPLN-PTLVASESALEQQTTPSSSPDVKVKLEGSVFLLDRESNSDGSFNRNEWQQVTKDSDFISASCEQQQDISVMTIPEHPDIHDLEKSVWELEGMPQDTYSQQLHSQIPESSLNEIQAQSSDQLPLQSELKEFESSVSQTNESYFPFDDELTQDSIVEELVLMEQQMSMNNSHSYGNCLGMTLQSQSVTPGAPMSSHGSSSHFYHPIHSNGTPIHTPTPTPTPTPTPTPTPTPTSEMIAGSQSLSRESPCSRLAQTTPVDSALGSSRHTPIGTPHSNCSSSVPPSPVECRNPFAFTPISSSMAYHDASIVSSSPVKPMQRPMATHPDKTKLEWMNNGYGGVGNSSVSGHGILPSYQELVEDRFRKPHAFAVPGQSYQSQSRHHDTHFGRLTPVSPVQHQGATVN-TNKQEGFAVPAPLDNKGTNSSASSNFRCRSVSPAVHRQRNLSGSTLYPVSNIPRSNVTPFGSPVTPEVHVFTNVHTDACANNIAQRSQSVPLTVMMQTAFPNALQKQTNSKKITNVLLSKLDSDNDDAVRGLGMNNVPSNYTARMNLTQILETSPVFPSANSQNMIDSSTSVYEFQTPSYLTKS-NSTDQISFSPGDNQAQSEIGEQQLDFNSTVKDLLSGDNLQTSQQLGGQVASDLTNTASDFPSDIRLSSDLSGSINDLNTLDPNLLFDPGRQQGQDDEATLEELKNDPLFQQICSESMNSMTSSGFEWIESKDHPTVEMLG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F8VPJ6-1", "uniprot_id": "RFX7_MOUSE", "id": "F8VPJ6-1", "name": "DNA-binding protein RFX7", "aln": "MAEEQQQPPPQQLDAPQQLPLSAPNP-GVALPALVPGLPGTEANALQHKIKNSICKTVQSKVDCILQEVEKFTDLEKLYLYLQLPSGLSSAEKSDQNAMSSSRAQQMHAFSWIRNTLEEHPETSLPKQEVYDEYKSYCDNLGYHPLSAADFGKIMKNVFPNMKARRLGTRGKSKYCYSGLRKKAFVHMPTLPNLDFHKTGDGLEGVEPSGQLQNIDEEVISSACRLVCEWAQKVLSQPFDTVLELAHFLVKSHYIGTKSMAALTVMAAAPAGLKGIPQPSAFIPTAESNSFQPQVKTLPSPIDAKQQLQRKIQKKQQEQKLQSPLPGESSAKKPEGTTANGVANLPNGNPAILSPQPIGIVVAAVPSPIPVQRTRQLVTSPSPMNSPDGKVLPLNVQVVTQHMQSVKQTPKTPQNVPASPGGDRSARHRYPQILPKPANTSALTIRSPTTVLFTSSPIKTAVVPASHMSSLNVVKMTTISLTPSNSNAPLKHSASVSSATGTTEESRIVPQIKNGSVVSLQSPGSRASSTGGTSAVEVKMEPEGSSDEHPLQCQENSEETKAPLTTSSALWGQKSNTDGTVPKPSNEGVTEVKTTKVCDQRTKCKNRCNEILSGISAGNNQSTVTLSVATQNLPFTSTSSPSNGDSVNKDPKICTKSPRKRLSATLQESQVPPVKKPIVEQLSAVTIEGQKPGTVKKDQKVPHSGKTESSTAGAQIPNKVSISVSSQIIEDQPVN-PALVTSEPVLEQQTTPSSSPDVKVKLEGSVFLLDRESKSDGSFNRNEWQQVTKDSDFIAASCEHQQDISVMTIAEHPDIHDLEKSVWELEGMPQDTYSQQLHSQIPESSLNEIQAQSSDQLPLQSELKEFESSVSQTNESYFPFDDELTQDSIVEELVLMEQQMSMNNSHSYGNCLGMSLQNQSVTPGAPMSSHASSTHFYHPIHSNGTPIHTPTPTPTPTPTPTPTPTPTSEMIAGSQSLSRESPCSRLAQTTPVDSALGSSRHTPIGTPHSNCSSSVPPSPVECRNPFAFTPISSSMAYHDASIVSSSPVKPMQRPMATHPDKTKLEWMNNGYGGVGNSSVSGHGILPSYQELVEDRFRKPHAFAVPGQSYQSQSRHHDTHFGRLTPVSPVQHQGATVN-TNKQEGFAVPAPLDNKGTNSSAGSNFRCRSVSPAVHRQRNLSGSTLYPVSNIPRSNVTPFGSPVTPEVHVFTNVHTDACANNIAQRSQSVPLTVMMQTAFPNALQKQTNSKKITNVLLSKLDSDNDDSVRGLGINNVPSNYTARMNLTQILETSPVFPSANSQNMIDSSTSVYEFQTPSYLTKS-NSTDQISFSPGDNQAQSEIGEQQLDFNSTVKDLLSGDNLQTSQQLVGQVASDLTNTASDFSSDIRLSSDLSGSINDLNTLDPNLLFDPGRQQGQDDEATLEELKNDPLFQQICSESMNSMTSSGFEWIESKDHPTVEMLG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q2KHR2-3", "uniprot_id": "RFX7_HUMAN", "id": "Q2KHR2-3", "name": "DNA-binding protein RFX7", "aln": "MAEEQQQPPPQQPDAHQQLPPSAPNS-GVALPALVPGLPGTEASALQHKIKNSICKTVQSKVDCILQEVEKFTDLEKLYLYLQLPSGLSNGEKSDQNAMSSSRAQQMHAFSWIRNTLEEHPETSLPKQEVYDEYKSYCDNLGYHPLSAADFGKIMKNVFPNMKARRLGTRGKSKYCYSGLRKKAFVHMPTLPNLDFHKTGDGLEGAEPSGQLQNIDEEVISSACRLVCEWAQKVLSQPFDTVLELARFLVKSHYIGTKSMAALTVMAAAPAGMKGITQPSAFIPTAESNSFQPQVKTLPSPIDAKQQLQRKIQKKQQEQKLQSPLPGESAAKKSESATSNGVTNLPNGNPSILSPQPIGIVVAAVPSPIPVQRTRQLVTSPSPMSSSDGKVLPLNVQVVTQHMQSVKQAPKTPQNVPASPGGDRSARHRYPQILPKPANTSALTIRSPTTVLFTSSPIKTAVVPASHMSSLNVVKMTTISLTPSNSNTPLKHSASVSSATGTTEESRSVPQIKNGSVVSLQSPGSRSSSAGGTSAVEVKVEPETSSDEHPVQCQENSDEAKAPQTP-SALLGQKSNTDGALQKPSNEGVIEIKATKVCDQRTKCKSRCNEMLPGTSTGNNQSTITLSVASQNLTFTSSSSPPNGDSINKDPKLCTKSPRKRLSSTLQETQVPPVKKPIVEQLSAATIEGQKQGSVKKDQKVPHSGKTEGSTAGAQIPSKVSVNVSSHIGANQPLNSSALVISDSALEQQTTPSSSPDIKVKLEGSVFLLDSDSKSVGSFNPNGWQQITKDSEFISASCEQQQDISVMTIPEHSDINDLEKSVWELEGMPQDTYSQQLHSQIQESSLNQIQAHSSDQLPLQSELKEFEPSVSQTNESYFPFDDELTQDSIVEELVLMEQQMSMNNSHSYGNCLGMTLQSQSVTPGAPMSSHTSSTHFYHPIHSNGTPIHTPTPTPTPTPTPTPTPTPTSEMIAGSQSLSRESPCSRLAQTTPVDSALGSSRHTPIGTPHSNCSSSVPPSPVECRNPFAFTPISSSMAYHDASIVSSSPVKPMQRPMATHPDKTKLEWMNNGYSGVGNSSVSGHGILPSYQELVEDRFRKPHAFAVPGQSYQSQSRHHDTHFGRLTPVSPVQHQGATVNNTNKQEGFAVPAPLDNKGTNSSASSNFRCRSVSPAVHRQRNLSGSTLYPVSNIPRSNVTPFGSPVTPEVHVFTNVHTDACANNIAQRSQSVPLTVMMQTAFPNALQKQANSKKITNVLLSKLDSDNDDAVRGLGMNNLPSNYTARMNLTQILEPSTVFPSANPQNMIDSSTSVYEFQTPSYLTKS-NSTGQINFSPGDNQAQSEIGEQQLDFNSTVKDLLSGDSLQTNQQLVGQGASDLTNTASDFSSDIRLSSELSGSINDLNTLDPNLLFDPGRQQGQDDEATLEELKNDPLFQQICSESMNSMTSSGFEWIESKDHPTVEMLG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4KGM5-1", "uniprot_id": "A0A0B4KGM5_DROME", "id": "A0A0B4KGM5-1", "name": "RFX-type winged-helix domain-containing protein", "aln": "MSEKHGQLGAQWTKSAAPAATTAPVSNSIPIPQPIP-----VALPLQKPNANPYGNCSLQPADIVYSATRFQGPAIHAKGSPLTITPVGPVGGAPASAQISPTSHTHVPVPVATPSGFVPPPFSNATSASGGVSTSVLTPNPFATASANAAGLAFANAFSFSTAQQLG-LGKIMHAMG----GATAGVPSAPVPVTTTPATAAPSTPTIAGPRHPNEGVPAASGVINSTIAENVMN----------------------ALSNSNSAGSVPSEEK-MRRVLQVIETSLDDNAKLQISQILERVSGLKPIEKLFLYLR--------LPGECADTDPLRQPQN-----PLGTRSEIN-HTINWVRSHLEHDAQVSIPKQDVYNDYIAYCERLSIKPLSTADFGKVMKQVFPGVR-----PRRLGTRGNSRYCYAAMR--------KTTKLTPPQLPQLCKTEQIVAGDSNSDPSQLTSASSLGGLPSTGGD-----SECWDVVRSWAEKLLNTKLESVADLSSRIKSNNATVSTKKYTPREPKEKRVLADIGPLKKRRKKKRKGSTSSESSCNQLVTGQDAGSSQEASDEQILKIKQEIIDSPIHPQQP---------PIGYLQQVTPMNLATD--------QRSSSAVRNLTPKILEMG---SPAVVLTQQEVSPTGIVIKDEVEDYTSNIFCKKVLKAQQTKGFWANSPSSGTTSGVGLLVPPTITTTSATPPPPN------------SETSPVPGPGLSMGPP-SQMMSTSSVSPSSTVDTTPKVASRNQMMILRAKRLMAAENAALAAAEDSGLPENLGLPRERVISICNMDKHELDDYFLPGEDEENSEEPDNELLQYFQMGDAEEKQLNSLDAAEQNKNPQEPPTMGSAPEAMPAPGRGAAVVAAAAAMLAPVPAPSMLPAQAGVGSASASLALMSKKHQQQNQHQNLQLQRSKQLPLISNNKRKISLSNASSNGSNKNCIFLPISPNTNGSVTTPTATGSSNPSQNCFASPGLTRMKQRPNLLSKQQSLDCDNRDPMIGAHRKGRGYVYSYPTSTSASAPPSPSILPQWMCRNWSLGGGNISSFADSSHSADPLVNQNSMDLETSLALTGENELDTSEMQRSQSVPLS-----------------QLQRRGSQQSPSLNFYSENSNSQQSAPLKETG-LLYEEVEVDSLLSANFTRKFNSITQQTATTCSSSAGSSSGYSSGGS--AGIVSRSVPSTPLPHQQQNSLTSLNGGGGAASSGGGVMGIGNGGNCGVGNGFFTISDSFNWEGSTSNNSQLGYAHSYSARNSLDISKSMPTTPIATQRFRYSPAEVHRDFLINGN--TIDSLPSSAFAGGVVPTDPTLALSTDTLIDDSAPSSADVVEAMIGVTGILDDFXNLHEEKAQGEIEISEQQEPDAVEENE-----VQSAAKEDANVVACLLQHVDQL---------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:*:: * .* .: . :** . .:.:* :* * .**: *. : . .* : . .. : : :. : .* *. :: ... : * * ... . .* : . ** * : *.*. .*::** ** :. . * . :*: * ... . .. . . :: :* * ::: : . *::*:. ::: . .:.*: * : : .* *: .:. : *:. : . :.. : ::: : : ****.: ... . * * *. : :. :.*. * : : *. .:* * . . .: **.. . : *:.* : * * .:*: *. : * : ... * . : *. *: .. ::.. :::. **... :. ... : :. .:::. : :* : ...:: : . : . * . :* *:: :.: . :. : *. ..: *: :.*:* : ::* : . : . * *.. .:.:*:: . ... * **: . : .* : :*.*. * :::. * : :* :*. . .:: .* : : *. .::: * * .:*:* ..*.:.: * :: . .. .:.: . :: :: *. : :.:: .*...: : * : .::*.. : .. :: . ...::* :: : * . :: :: .: :: . * : . .: .: *: *. . . *:: . : : * .. * : . . ::.:.* . :. * *. :. .:.:: :. * ..* .** :* : :: * : . * . :*. * : : . .* .. : . : .. * * :.*: : .. : :: :: : : .:: . ..: ..* . *:.:*::.*.. ** ... .. : :* ** :: : * ... .: :.. :.:.... . * . : ::. :.*.: : :.:.:*.: . :.....* *:* .. . .. :.::: :: . .. . . .* :: .:: .. :..: :* :: :**.: : : *. : ::* .. ::*. : *. * . : : ::*.. .. :. ::* ::*: .*. : . . . *:: ::** : * .::. .:.:. :: ::. ", "identical_positions": 157, "similar_positions": 548, "identity": "10.73%" }, { "cls_id": "homologset.agr.RGD:1308796", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q6NT55-1", "uniprot_id": "CP4FN_HUMAN", "id": "Q6NT55-1", "name": "Ultra-long-chain fatty acid omega-hydroxylase", "aln": "MLPITDRLLHLLGLEKTAFRIYAVSTLLLFLLFFLFRLLLRFLRLCRSFYITCRRLRCFPQPPRRNWLLGHLGMYLPNEAGLQDEKKVLDNMHHVLLVWMGPVLPLLVLVHPDYIKPLLGASAAIAPKDDLFYGFLKPWLGDGLLLSKGDKWSRHRRLLTPAFHFDILKPYMKIFNQSADIMHAKWR-HLAEGSAVSLDMFEHISLMTLDSLQKCVFSYNSNCQEKMSDYISAIIELSALSVRRQYRLHHYLDFIYYRSADGRRFRQACDMVHHFTTEVIQERRRALRQQGAEAWLKAKQGKTLDFIDVLLLARDEDGKELSDEDIRAEADTFMFEGHDTTSSGISWMLFNLAKYPEYQEKCREEIQEVMKGRELEELEWDDLTQLPFTTMCIKESLRQYPPVTLVSRQCTEDIKLPDGRIIPKGIICLVSIYGTHHNPTVWPDSKVYNPYRFDPDNPQQRSPLAYVPFSAGPRNCIGQSFAMAELRVVVALTLLRFRLSVDRTRKVRRKPELILRTENGLWLKVEPLPPRA------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A1W2Q6E6-1", "uniprot_id": "A0A1W2Q6E6_RAT", "id": "A0A1W2Q6E6-1", "name": "Cytochrome P450 4F22", "aln": "MLPITDYLLYLLGLEKTAFRVYVLSALLLFLLFLLFRLLLQAFKLFSDFRITCRRLSCFPEPPGRHWLLGHMSMYLPNEKGLQNEKKVLDTMHHIILAWVGPFLPLLVLVHPDYIKPVLGASAAIAPKDEFFYSFLKPWLGDGLLISKGNKWSRHRRLLTPAFHFDILKPYMKIFNQSVNIMHAKWRRHLAEGSVTSFDMFEHVSLMTLDSLQKCVFSYSSDCQEKLSDYISSIIELSALVVRRQYRLHHYLDFIYYLTADGRRFRQACDTVHNFTTEVIQQRRRALRELGAEAWLKAKQGKTLDFIDVLLLAKDEEGKELSDEDIRAEADTFMFEGHDTTSSGLSWALFNLAKYPEYQDKCREEIQEVMKGRELEELDWDDLTQLPFTTMCIKESLRQFPPVTLISRRCTEDIKLPDGRIIPKGIICLVSIYGTHYNPLVWPDSKVYNPYRFDPDIPQQRSPLAFVPFSAGPRNCIGQSFAMAEMRVVVALTLLRFRLSVDRTRKVRRKPELILRTENGLWLNVEPLPSRAGVPRGPTEPEVQAPPAQA", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****** **:**********:*.:*:*******:******: ::* .* ****** ***:** *:*****:.****** ***:******.***::*.*:**.**************:***********::**.***********:***:****************************.:******* ******..*:*****:***************.*:****:*****:******* **************** :*********** **:*******:******: ***********************:**:***************************:** ***********:******************:********************:*****:**:***************************:** **************** ********:*******************:*************************************:*****.** ", "identical_positions": 462, "similar_positions": 54, "identity": "84.0%" }, { "cls_id": "homologset.agr.RGD:1308800", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P32577-1", "uniprot_id": "CSK_RAT", "id": "P32577-1", "name": "Tyrosine-protein kinase CSK", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSAIQASWPSGTECIA---------------------------------------KYNFHGTAEQDLP--------FCKGDVLTIVAVTKDPNWYKAKNKVGREG-----------IIPANYVQKREGVKAG-------------------------------TKLSLMPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCEGKVEHYRIMYHASKLSIDEEVYFENLMQLVEHYTTDADGLCTRLIKPKVMEG---TVAAQDEFYRSGWALNMKELKLLQTIGKGEFGDVMLGDYRGNKVAVKCIKNDATAQAFLAEASVMTQLRHSNLVQLLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLEGNNFVHRDLAARNVLVSEDNVAKVSDFGLTKEASSTQDTGKLPVKWTAPEALREKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVEKGYKMDAPDGCPPAVYDVMKNCWHLDAATRPTFLQLREQLEHIRTHELHL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P41241-1", "uniprot_id": "CSK_MOUSE", "id": "P41241-1", "name": "Tyrosine-protein kinase CSK", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSAIQAAWPSGTECIA---------------------------------------KYNFHGTAEQDLP--------FCKGDVLTIVAVTKDPNWYKAKNKVGREG-----------IIPANYVQKREGVKAG-------------------------------TKLSLMPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCEGKVEHYRIMYHASKLSIDEEVYFENLMQLVEHYTTDADGLCTRLIKPKVMEG---TVAAQDEFYRSGWALNMKELKLLQTIGKGEFGDVMLGDYRGNKVAVKCIKNDATAQAFLAEASVMTQLRHSNLVQLLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLEGNNFVHRDLAARNVLVSEDNVAKVSDFGLTKEASSTQDTGKLPVKWTAPEALREKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVEKGYKMDAPDGCPPAVYEVMKNCWHLDAATRPTFLQLREQLEHIKTHELHL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P41240-1", "uniprot_id": "CSK_HUMAN", "id": "P41240-1", "name": "Tyrosine-protein kinase CSK", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSAIQAAWPSGTECIA---------------------------------------KYNFHGTAEQDLP--------FCKGDVLTIVAVTKDPNWYKAKNKVGREG-----------IIPANYVQKREGVKAG-------------------------------TKLSLMPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCDGKVEHYRIMYHASKLSIDEEVYFENLMQLVEHYTSDADGLCTRLIKPKVMEG---TVAAQDEFYRSGWALNMKELKLLQTIGKGEFGDVMLGDYRGNKVAVKCIKNDATAQAFLAEASVMTQLRHSNLVQLLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLEGNNFVHRDLAARNVLVSEDNVAKVSDFGLTKEASSTQDTGKLPVKWTAPEALREKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVEKGYKMDAPDGCPPAVYEVMKNCWHLDAAMRPSFLQLREQLEHIKTHELHL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8INJ8-1", "uniprot_id": "Q8INJ8_DROME", "id": "Q8INJ8-1", "name": "Tyrosine-protein kinase", "aln": "MVTTIKITCDGVFIQSNSYLMPTPSPSGADATVSSSLERVLKPASASASPSNSNNESDNSQTSSGSQTASSASKRSNRSVGRSHRGSIAQDTRRRYYFGSKDIYWCKQSREAAAAATLSGSGLTRSASSVTHKEASTHATHTGGQVISRARRKPILLCSSLSAAYAPPRRREFYFCDKYAPGPARSTPTTTTTSATSAKHESSPPIDARLLNFLRCAHRKFQASKAKTELQQTKDRFLGNSRERTSKNGQQTSRSLPPIASSEEWFDEEAQARKTSHEKSQKPKPKPEENHKEKEAISRKASGEGDLITVEIKQGLLRKQTATTTTGQAMNSHATATQNGQTTVVGHHRGFSQPSVTVAAAAATGSTAGDPWFLQTTGHQMPPTAPLRHNKRPAPQPNAVLGAGSSGTAPGSAVGAVLLHQQQLSQSQPHIVPPSIPPHHHHHRENNVHPIQAGAAAALHLSSHALNSHNLISSASNHSPKSPSQTQQQQQTTNQQQQQQQQQASHSILSTFAPAPTVAAVQPAGSQSVAGTAAAVAAVAQQQQQQHLQLLANCPPGGAGLMSSSLNAAQMGMHG-AERALPPKSLALSGSQHGSNMLLHTAPQPPQASQPAAVVGVSGSGSAGMSTSLHSFDINGVTAGSGVNASSAWSSGSTTAMNHASLSPTALAPQQGRSRCEVKLNAMPWFHGSITRDEAEHLLQPREDGLFLVRESTNFPGDYTLCVCFQSKVEHYRVKYLENKLTIDDEEYFENLGQLVAHYEADADGLCTQLIKCLPKLGKQEFCINSKDFVDKGWVIPEAELQLRESIGKGEFGDVMLGILRNEKVAVKMLKDEGAVQKFLAEASVMTTLEHDNLVKFIGLVFTSK-HLYLVTEYMSKGSLVDYLRSRGRQHITKKDQIIFAYDTASGMEYLEAKKVVHRDLAARNVLISEDCVAKVSDFGLAREECYNLDVGKLPIKWTAPEALKNGRFSNKSDMWSFGILLWEIYSFGRVPYPRIPLADVVKHVEVGYKMEAPEGCPPEIYEMMRQAWDLNPAKRPTFAELKVKLQLLNNATA--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:: * *:*::.:* : .:** **: ** :*. : : :..: *: :. ** .* : * * .**:*. .**. ******.***::**:** * * **********:********. :.******: * .**:**:* ***** *** ** :*******:*** * ..:* .**.: **:* ::************ *.:***** :*::.:.* ********* *.*.***:::*::. .* **:*****:*************. : . : *: *....*****.::.***********:*** *********::* . . *.****:********:: :**.***:*********************** *** :** ****:**:**** :*::*::.*.*:.* **:* :*: :*: :.. ", "identical_positions": 247, "similar_positions": 117, "identity": "23.39%" }, { "cls_id": "homologset.agr.RGD:1308801", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8C0Q4-1", "uniprot_id": "NEK11_MOUSE", "id": "Q8C0Q4-1", "name": "Serine/threonine-protein kinase Nek11", "aln": "MLKFQETAKCVGRRPTVIPMYPTALIARRYVLQQKLGSGSFGTVYLVSDKKAKPGEELKVLKEISVGELNPNETVQANVEAQLLSRLHHPAIVRFHASFMEQETFCIITEYCEGRDLDYRIQEYKEAGKVFAENQIVEWFIQLLLGVDYMHERRILHRDLKSKNIFLKNNLLKIGDFGVSRLLMGSCELATTLTGTPHYMSPEALKHQGYDAKSDIWSLACILYEMCCLDHAFAGSSFLSVVLNIVEGKTPSLPDRYPRELNTIMERMLNKSPSLRPSAADILKAPYMEEQLQLLMCKYPEMTLEDK-NSVCQKEAAHTINAVQKKLHLQTLQALSDTQKTTPRERMWLRKLQAADERARRLKKIAEEN-YKENDKRMQALRSRNVGSVHAHVLHEL------------------------------------DERTLESLPEPQSLPCLDLDELEPSLEDTIVDLGHYEIPEDPLVAEQYYSDVFDSCSEDSEEQEEEMIFSEAGGDTKEEESPSVYRTNQQDSDTAALVGCLEHVLGYTSLDTKTITNAVTDMSPGPMVFNSAVARTKMKRMKESAVQKLGMETFEEVYDYLKRARHQNAREAEIWEHLETVVPRASDCFEVDQLLYFEELLLTMEGKEPSLQNLPCEAAQKKPVKGTHFCDNP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A3H8-1", "uniprot_id": "D4A3H8_RAT", "id": "D4A3H8-1", "name": "Serine/threonine-protein kinase Nek11", "aln": "MLKFQETAKCG---PTAIPVYPPTVIARRYVLQQKLGSGSFGTVYLVSDKKAKHGEELKVLKEISVGELNPNESVQASMEAQLLSTLNHPAIVRFHESFMEQGTFCIITEYCEGRDLDYKIQEYKEAGKIFPDNQIVEWFIQLLLGVDYMHERRILHRDLKSKNIFLKNNLPKIGDFGVSRLLMGSCELATTLTGTPYYMSPEALKHQGCDAKSDIWSLACILYEMCCMDHAFSGSNFLSVVLNIVEGNTPSLPDRYPRELNIIMSRMLNKSPSLRPSAAEILKAPYVEERLQQLMYKHPEATLEDKRNSACQKEAAHAVNAMQREIYLQTLRALCVVQKITPTERVWPRKLQAADERARRLKKITEGRRYKENNKRAKELRSQNFGSVSAHVLQEL------------------------------------DELTLESLSQPQSLPCLNLDELEPSLEGTIVDLGHYEIPEDPLVAEQYYADVFDSCSEDSGEQEEEMAFSEAGGDMREEGSPPTYRTNQQDSDTDALVGCLEHVLGYTSLDTKTNTSAVADVSPGPTVFNSAMARTKVKRMKESAVQKLGTETFEEVYDYLKRARHQNAREAEIWEHLETVVPLASDCFEVDQLLYFEELLLTMEGKESSLQSPHCEACRKKPVKSIHFCDNS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NG66-1", "uniprot_id": "NEK11_HUMAN", "id": "Q8NG66-1", "name": "Serine/threonine-protein kinase Nek11", "aln": "MLKFQEAAKCVSG-STAISTYPKTLIARRYVLQQKLGSGSFGTVYLVSDKKAKRGEELKVLKEISVGELNPNETVQANLEAQLLSKLDHPAIVKFHASFVEQDNFCIITEYCEGRDLDDKIQEYKQAGKIFPENQIIEWFIQLLLGVDYMHERRILHRDLKSKNVFLKNNLLKIGDFGVSRLLMGSCDLATTLTGTPHYMSPEALKHQGYDTKSDIWSLACILYEMCCMNHAFAGSNFLSIVLKIVEGDTPSLPERYPKELNAIMESMLNKNPSLRPSAIEILKIPYLDEQLQNLMCRYSEMTLEDK-NLDCQKEAAHIINAMQKRIHLQTLRALSEVQKMTPRERMRLRKLQAADEKARKLKKIVEEK-YEENSKRMQELRSRNFQQLSVDVLHEKTHLKGMEEKEEQPEGRLSCSPQDEDEERWQGREEESDEPTLENLPESQPIPSMDLHELESIVEDATSDLGYHEIPEDPLVAEEYYADAFDSYCEESDEEEEEIALERPEKEIRNEGSQPAYRTNQQDSDIEALARCLENVLGCTSLDTKTITTMAEDMSPGPPIFNSVMARTKMKRMRESAMQKLGTEVFEEVYNYLKRARHQNASEAEIRECLEKVVPQASDCFEVDQLLYFEEQLLITMGKEPTLQNHL------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******:*** .*.*. ** ::**************************** *******************:***.:****** *.*****:** **:** .************** :*****:***:*.:***:***************************:****** ***************:*********:*********** *:****************::***:**.***:**:****.*****:***:*** **. ****.******* :*** **::*:** ** ::.* ***** * ******* :**:*:.::****:**. .** ** **: ********:**:****.* . *:**.** : ***:*. .: ..**:* ** ***.*.:.*.:*.::*.***. :*.: ***::**********:**:*.*** .*:* *:***: :... : ::* * ..********* **. ***:*** ******* *. . *:**** :***.:****:***:***:**** *.*****:********** **** * **.*** *************** ** ***.:**. ", "identical_positions": 431, "similar_positions": 114, "identity": "64.71%" }, { "cls_id": "homologset.agr.RGD:1308802", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K479-1", "uniprot_id": "C1QT5_MOUSE", "id": "Q8K479-1", "name": "Complement C1q tumor necrosis factor-related protein 5", "aln": "MRPLLALLLLGLVSGSPPLDDNKIPSLCPGQPGLPGTPGHHGSQGLPGRDGRDGRDGAPGAPGEKGEGGRPGLPGPRGEPGPRGEAGPMGAIGPAGECSVPPRSAFSAKRSESRVPPPADTPLPFDRVLLNEQGHYDPTTGKFTCQVPGVYYFAVHATVYRASLQFDLVKNGQSIASFFQYFGGWPKPASLSGGAMVRLEPEDQVWVQVGVGDYIGIYASIKTDSTFSGFLVYSDWHSSPVFA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5FVH0-1", "uniprot_id": "C1QT5_RAT", "id": "Q5FVH0-1", "name": "Complement C1q tumor necrosis factor-related protein 5", "aln": "MRPLLALLLLGLASGSPPLDDNKIPSLCPGQPGLPGTPGHHGSQGLPGRDGRDGRDGAPGAPGEKGEGGRPGLPGPRGEPGPRGEAGPVGAIGPAGECSVPPRSAFSAKRSESRVPPPADTPLPFDRVLLNEQGHYDATTGKFTCQVPGVYYFAVHATVYRASLQFDLVKNGQSIASFFQFFGGWPKPASLSGGAMVRLEPEDQVWVQVGVGDYIGIYASIKTDSTFSGFLVYSDWHSSPVFA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BXJ0-1", "uniprot_id": "C1QT5_HUMAN", "id": "Q9BXJ0-1", "name": "Complement C1q tumor necrosis factor-related protein 5", "aln": "MRPLLVLLLLGLAAGSPPLDDNKIPSLCPGHPGLPGTPGHHGSQGLPGRDGRDGRDGAPGAPGEKGEGGRPGLPGPRGDPGPRGEAGPAGPTGPAGECSVPPRSAFSAKRSESRVPPPSDAPLPFDRVLVNEQGHYDAVTGKFTCQVPGVYYFAVHATVYRASLQFDLVKNGESIASFFQFFGGWPKPASLSGGAMVRLEPEDQVWVQVGVGDYIGIYASIKTDSTFSGFLVYSDWHSSPVFA", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****.******.:****************:***********************************************:********* *. **************************:*:********:*******..*********************************:*******:**************************************************************", "identical_positions": 228, "similar_positions": 13, "identity": "93.83%" }, { "cls_id": "homologset.agr.RGD:1308804", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q80UU9-1", "uniprot_id": "PGRC2_MOUSE", "id": "Q80UU9-1", "name": "Membrane-associated progesterone receptor component 2", "aln": "MAAGDGDVKLSTLGSGGESGGDG---SPGGAGATAARSSWVAA---LLATGGEMLLNVALVALVLLGAYRLWVRWGRRGLCSGPGAGEESPAATLPRMKKRDFSLEQLRQYDGAR-TPRILLAVNGKVFDVTKGSKFYGPAGPYGIFAGRDASRGLATFCLDKDALRDE---YDDLSDLNAVQMESVREWEMQFKEKYDYVGRLLKPGEEPSEYTDEED-------------------TKDHSKQD--------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5XIU9-1", "uniprot_id": "PGRC2_RAT", "id": "Q5XIU9-1", "name": "Membrane-associated progesterone receptor component 2", "aln": "MAAGDGDVKLSTLGSGGERGGDG---SPGGAGATAARSSWVAA---LLATGGEMLLNVALVALVLLGAYRLWVRWGRRGLCSGPGAGEESPAATLPRMKKRDFSLEQLRQYDGAR-TPRILLAVNGKVFDVTKGSKFYGPAGPYGIFAGRDASRGLATFCLDKDALRDE---YDDLSDLNAVQMESVREWEMQFKEKYDYVGRLLKPGEEPSEYTDEED-------------------TKDHSKQD--------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O15173-1", "uniprot_id": "PGRC2_HUMAN", "id": "O15173-1", "name": "Membrane-associated progesterone receptor component 2", "aln": "MAAGDGDVKLGTLGSGSESSNDGGSESPGDAGAAAEGGGWAAAALALLTGGGEMLLNVALVALVLLGAYRLWVRWGRRGLGAGAGAGEESPATSLPRMKKRDFSLEQLRQYDGSR-NPRILLAVNGKVFDVTKGSKFYGPAGPYGIFAGRDASRGLATFCLDKDALRDE---YDDLSDLNAVQMESVREWEMQFKEKYDYVGRLLKPGEEPSEYTDEED-------------------TKDHNKQD--------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VXM4-1", "uniprot_id": "Q9VXM4_DROME", "id": "Q9VXM4-1", "name": "", "aln": "MDS--------KVGADPSSAYDK----EIGNNLNNDDSSFLGN---IIREILYSPMNLALLAIICFLVYKIVR---DRTEVPSVGVAKPS-EPELPKIR-RDFTVKELRQYDGTQPDGRVLVAVNGSVYDVSKGRRFYGPGGPYATFAGRDASRNLATFSVVS-IDKDE---YDDLSDLSAVEMDSVREWEMQFKEKYELVGKLLRKGEEPTNYDDDEDEENVNNDEQERKNLPKSKTETDDTKQEKESHILQSNVTNKNNAQDQATPSTDC", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12091-1", "uniprot_id": "DAP1_YEAST", "id": "Q12091-1", "name": "Damage response protein 1", "aln": "---------------------------------------------------------MSFIKNLLFGGVKTSE--DPTGLTGNGASNTNDSNKGSEPVVAGNFFPRTLSKFNGHD-DEKIFIAIRGKVYDCTRGRQFYGPSGPYTNFAGHDASRGLALNSFDLDVIKDWDQPIDPLDDLTKEQIDALDEWQEHFENKYPCIGTLIP---EPGVNV---------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :::: : : : . . . : :* . * :::* ::::*:.*.*:* ::* :****.*** ***:****.** .. :* * *.**. ::::: **: :*::** :* *: ** ", "identical_positions": 38, "similar_positions": 46, "identity": "13.97%" }, { "cls_id": "homologset.agr.RGD:1308805", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5M836-1", "uniprot_id": "LYSM3_RAT", "id": "Q5M836-1", "name": "LysM and putative peptidoglycan-binding domain-containing protein 3", "aln": "MAGRNQNRTASLA-GIQ--ASGHVHTFGNCTDNDMLEEDAEVYELRSRGKEKVRRSTSRDRLDDIVILTKDIQEGDTLNAVALQYCCTVADIKRVNNLISDQDFFALRSIKIPVKRFSSLTETLH--PLKGRQVLHPPPVPYFQEQ-DTVPANDSPSSSESAGSFLKEVDRDIEQIVKCTDTKKENLNEVVSALTAQQVRFEPDNKSVHRKDPYYGADWGMGWWTAVVIMLIVGIITPVFYLLYYEILAKVDVSHHSTVDSSHLHPGLTPPSHHREMGNAIGPTKGIPVGQQDDHRLYRQDPQARD------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99LE3-1", "uniprot_id": "LYSM3_MOUSE", "id": "Q99LE3-1", "name": "LysM and putative peptidoglycan-binding domain-containing protein 3", "aln": "MAGRNQNRTVSLP-GIQ--ASGHVLAFGNCTDNDMLEEDAEVYELRSRGKEKVRRSASRDRLDDIVILTKDIQEGDTLNAVALQYCCTVADIKRVNNLISDQDFFALRSIKIPVKRFSSLTETLH--PLKGRHILHPPPVPYFQEQ-DIVPADGSLSSSESAGSFLKEVDRDIEQIVKCTDTKKENLNEVVSALTAQQVRFEPDNKSIHRKDPYYGADWGIGWWTAVVIMLIVGIITPVFYLLYYEILAKVDVSHHSTVGSSHLHPGLTPPTQHREMENEIGPTKGIPVGQQDDHKLYRQDPQAHDAQHKT-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z3D4-1", "uniprot_id": "LYSM3_HUMAN", "id": "Q7Z3D4-1", "name": "LysM and putative peptidoglycan-binding domain-containing protein 3", "aln": "MAGRHQNRSFPLP-GVQ--SSGQVHAFGNCSDSDILEEDAEVYELRSRGKEKVRRSTSRDRLDDIIVLTKDIQEGDTLNAIALQYCCTVADIKRVNNLISDQDFFALRSIKIPVKKFSSLTETLC--PPKGRQTSRHSSVQYSSEQQEILPANDSLAYSDSAGSFLKEVDRDIEQIVKCTDNKRENLNEVVSALTAQQMRFEPDNKNTQRKDPYYGADWGIGWWTAVVIMLIVGIITPVFYLLYYEILAKVDVSHHSTVDSSHLHSKITPPSQQREMENGIVPTKGIHFSQQDDHKLYSQDSQSPAAQQET-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6IQA2-1", "uniprot_id": "LYSM3_DANRE", "id": "Q6IQA2-1", "name": "LysM and putative peptidoglycan-binding domain-containing protein 3", "aln": "MTGRNQHNGFQFATAVQPATGAYMSAFGNNSETEYSEEDGEAFELRSRGRERHHRSTSRDRKDDIVYLIREIKEGDTLISISLQYFCTVADIKRANNLLTEQDFFALRSLRIPVRKFSSFTETHNTAPHKSSSPSGTCRITETPVSGASLDSTSSSSSADSVECFLQEKDKDIQQLVKSSAPSRNSLSEVVSSLEQPLLG-DAERRPAIKKDPYYGADWGMRWWTAVAIMLVVGIVTPVFYLLYYEVLMKADVSHHTTIDS--IRPGPTQP----AIAEPLVLPQANAAPHQDSHLLPVIEQQHHVKHQEET", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:**:*:. :. .:* :.. : :*** ::.: ***.*.:******:*: :**:**** ***: * ::*:***** :::*** ********.***:::********::***::***:*** * *. : . : : .* : ::*. .**:* *:**:*:**.: .::.*.****:* : :.:.: :**********: *****.***:***:**********:* *.*****:*:.* ::. * * : : : .:. :**.* * : * ", "identical_positions": 132, "similar_positions": 91, "identity": "42.31%" }, { "cls_id": "homologset.agr.RGD:1308806", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A5K9-1", "uniprot_id": "A0A8I6A5K9_RAT", "id": "A0A8I6A5K9-1", "name": "", "aln": "MSSDDSSLMASIIYYCQEKYFHHVLQAANVGLERYSCDPVLQFFRAYGVLGEDRIHDAISELESLQSHPDTSLCAVIALLYAHKCCDTIDAEAIQELDSSLKEIRRTASGMALYYASLFLWFMGHHDKAREYVDHMLKVSSGSKEGYVLKGWVDLTSNKPHVVKKSIKYLEQGTQDTKDVLGLMGKAKYFMTQQNFSGALEVVNQVTLAYSNFLPALVLKMKLFLARQDWEQTIETGQRILEKDENNIDAWQILAVHELVKEG--------NTDRAADRVRNLIKALETGEPQNPNLHLKKILAVSRLCGRHQVVHRLVSGFLERTFMATPSCALVATELGYLFILQQQVKEASLWYKEAMKLEENRLAALAGSIWCQILQGQLEEAAHQLEFLKEVQLSLGKSEVLVFLQALVAAKKQKLEQEATALLKEAVELHFSNMQGLALSPEYFEKLDPLFLVCIAKEYLHFCPKQPRSPGQLVSPLLKQVAMILSPVVKVAPAMMEPLFVTAQVKFLSGELENAQSTLQRCLELDPTFVDAHLLMSQIYLAQGNFAMCSHCLELGVSHNFQVRDHPLYHFIKARALNKTGDYAEAIKTLKMIIKVPTSKAEEGRKSRGPSVRPSERASILLELVEALRLNGELHEATKIMQDAINEFSGTPEEMRITVANVDLALSKGNADLALNMLRGITPKQPCYTEAKEKMASIYLHTRKDVRLYIGCYMELCEHLPGPHSSLLLGDAFMNIQEPEKALEVYDEAYRKNPHDASLVSRIGQAYVKTHQYAKAINYYEAAQKISGQD-FLCCELAELLLKLKKYHKAEKVLKQALERDSGVKDIPSLMDEVKCLLLLAKVYKSHKKEDVMETLNQALDLQSRILKRVPLEQPEMIPSQNQVAASICVQIGEHHLADKDYDSAMKSYKDALAYSPTDSKVVLELAQLYLLQGQLDLCEQHCAPLLEMEQTHERAAVVLADLMFRKQNYETAINLYRQVLEKAPDNFLVLNKLIDLLRRSGKLEEAPAFFELAKKVSSRVPLEPGFNYCQGIYCWHIGQPNEALRFLNKARKDSTWGQLATCYMVQICLNPDNEIVGGEAFESLVGDSNSASRKESQQHGVRTAEKLLREFYPHSESGQTQLRLLQSLCLLATREKANIEVALGAFIEMAQAEKDNIPALLAMAQAYVLLKQVPKARTQLKRLAKVPWMLDEAEDLEKSWLLLADIYCQGGKFDLALELLRRCLQYNKSCCRAYEYMGFIMEKEQSYKDAATNYELAWKYSHQANPAIGFKLAFNYLKDKKFVDAIEVCHSVLTEYPNYPKIREEILEKAQGSLRP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C0S4-1", "uniprot_id": "TT21A_MOUSE", "id": "Q8C0S4-1", "name": "Tetratricopeptide repeat protein 21A", "aln": "MSSDDSSLMASIIYYSQEKYFHHVLQAANVGLERYSSDPALQFFRAYGILGEDHIHDAISELEGIQSHPDTSLCAVIALLSAHKSCDTIDIEAVQELESSLKEIRRSASSTALYYASLFLWFMGHHDKAREYVDHMLKVSSGSKEGYVLKGWVDLTSSKPHVVKKSIKYLEQGTQDTKDVLGLMGKATYFMTQQNFSGALEVANQVTLACSNFLPALVLKMKLFLARQDWDQTIETGQRILEKDENNIDAWQILAVHELVKEG--------NTDRAADRVRNLIKALETGEPHNPNLHLKKILVISRLCGRHQVVHRLVSGFLERIFMATPSCALVATELGYLFILHQQVKEACLWYKEAMKLEENRLAALAGSIWCQILQGQLEEAAHQLEFLKEVQQSLGKSELLVFLQALVAAKKQRLEQEATALLKEAVEVHFSSMQGLALSPEYFEKLDPLFLVCIAKEYLHFCPKQPRSPGQLVSPLLKQVAMILSPVVKVAPAMMEPLYVTAQVKFLSGELENAQSTLQRCLELDPTFVDAHLLMSQIYLAQGNFAMCSHCLELGVSHNFQVRDHPLYHFIKARALNKTGDYAEAIKTLKMIIKVPTSKAEEGRKSQSPSVRPSERASILLELVEALRLNGELHEATKIMQDAINEFSGTPEEMRITVANVDLALSKGNVDLALNMLRGITPKQPCYTEAKEKMASIYLHTRKDVRLYIGCYVELCEHLPGPHSSLLLGDAFMNIQEPEKALEVYDEAYRKNPHDASLVSRIGQAYVKTHQYAKAINYYEAAQKISGQD-FLCCELAELLLKLKKYHKAEKVLKQALERDSGVKDIPSMINEVKCLLLLAKVYKSHKKEEVMETLNLALDLQSRILKRVPLEQSEMIPFQNQLAASICIQIGEHHLAEKDYDSALKSYKDALAYSPTDSKVVLELAHLYLLLGQLDLCEQRCAPLLEMEQTHERAAVMLADLMFRRQNYETAINLYHQVLEKAPDNFLVLNKLVDLLRRSGKLEEAPAFFELAKKVSSRVPLEPGFNYCQGIYFWHIGQPNEALRFLNKARKDSTWGQLATCYMVQICLNPDNEIVGGEAFESLVGDSNSASRKESQQHGVRTAEKLLREFYPHSESGQTQLRLLQNLCLLATREKANVEVALGAFIEMAQAEKDSIPALLAMAQAYILLKQVPKARTQLKRLAKVPWTVDEAEDLEKSWLLLADIYCQGGKFDLALELLRRCLQYNKSCCRAYEYMGFIMEKEQSYKDAATNYELAWKYSHQANPAIGFKLAFNYLKDKKFVDAIEVCHSVLTEHPKYPKIREEILEKAQGSLRP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NDW8-1", "uniprot_id": "TT21A_HUMAN", "id": "Q8NDW8-1", "name": "Tetratricopeptide repeat protein 21A", "aln": "MSSNDSSLMAGIIYYSQEKYFHHVQQAAAVGLEKFSNDPVLKFFKAYGVLKEEHIQDAISDLESIRHHPDVSLCSTMALIYAHKRCEIIDREAIQELEYSLKEIRKTVSGTALYYAGLFLWLIGRHDKAKEYIDRMLKISRGFREAYVLRGWVDLTSDKPHTAKKAIEYLEQGIQDTKDVLGLMGKAMYFMMQQNYSEALEVVNQITVTSGSFLPALVLKMQLFLARQDWEQTVEMGHRILEKDESNIDACQILTVHELAREGNMTTVSSLKTQKATNHVRNLIKALETREPENPSLHLKKIIVVSRLCGSHQVILGLVCSFIERTFMATPSYVHVATELGYLFILKNQVKEALLWYSEAMKLDKDGMAGLTGIILCHILEGHLEEAEYRLEFLKEVQKSLGKSEVLIFLQALLMSRKHKGEEETTALLKEAVELHFSSMQGIPLGSEYFEKLDPYFLVCIAKEYLLFCPKQPRLPGQIVSPLLKQVAVILNPVVKAAPALIDPLYLMAQVRYYS-ELENAQSILQRCLELDPASVDAHLLMCQIYLAQGNFGMCFHCLELGVSHNFQVRDHPLYHLIKARALNKAGDYPEAIKTLKMVIKLPALKKEEGRKFLRPSVQPSQRASILLELVEALRLNGELHEATKVMQDTINEFGGTPEENRITIANVDLVLSKGNVDVALNMLRNILPKQSCYMEAREKMANIYLQTLRDRRLYIRCYRELCEHLPGPHTSLLLGDALMSILEPEKALEVYDEAYRQNPHDASLASRIGHAYVKAHQYTEAIEYYEAAQKINGQD-FLCCDLGKLLLKLKKVNKAEKVLKQALEHD-IVQDIPSMMNDVKCLLLLAKVYKSHKKEAVIETLNKALDLQSRILKRVPLEQPEMIPSQKQLAASICIQFAEHYLAEKEYDKAVQSYKDVFSYLPTDNKVMLELAQLYLLQGHLDLCEQHCAILLQTEQNHETASVLMADLMFRKQKHEAAINLYHQVLEKAPDNFLVLHKLIDLLRRSGKLEDIPAFFELAKKVSSRVPLEPGFNYCRGIYCWHIGQPNEALKFLNKARKDSTWGQSAIYHMVQICLNPDNEVVGGEAFENQGAESNYMEKKELEQQGVSTAEKLLREFYPHSDSSQTQLRLLQGLCRLATREKANMEAALGSFIQIAQAEKDSVPALLALAQAYVFLKQIPKARMQLKRLAKTPWVLSEAEDLEKSWLLLADIYCQGSKFDLALELLRRCVQYNKSCYKAYEYMGFIMEKEQSYKDAVTNYKLAWKYSHHANPAIGFKLAFNYLKDKKFVEAIEICNDVLREHPDYPKIREEILEKARRSLRP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9P6A7-1", "uniprot_id": "A0A8M9P6A7_DANRE", "id": "A0A8M9P6A7-1", "name": "", "aln": "MSEEDKTCLPLIIYYMRERYYRHAINTAARSLKVYNNDPVLRFFKAFATLMEGHSQEALQELILLKDHPHLSLCSTVALIYAHKHCETVDEDAVNELNSELKRSGSTAGERALYYAALIYWILQMNLKAKTCIKKMLKISETSPEGLIMKGWIVLTSDLEENRPQAIRYFNSGVRDSGNLFGLMGKIEFFMLKQNESSALDIIHQILLIYPDFTPALLMKMKIFMALQDYEQTEDIAHRVLERDAQDLKALQMLTVIAVVKDG--------DTELVKQRQQALVSALELREPCNPSLHVEITAVISRL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IRDQFQFNLIKAQALLRSGDVKSAIQCLNLIMKMPGVQGP-SEGPQSSIISSSERLCVFLQLSEALRVNGDQHEAAKVLEDAVVFFRGMPEETQLTLAHVDLALTRDDVDAAVLILQNILPTESSYIQAREKMAHIYLERRNDKKLFIACYKEITEQLPGAHTSILLADAFMKIHQPEEAARIYQEVETIAP-KCTLTKKIGHALVKAHEYDKAVCYYETALRRDSLDCVLSLELSELLLKLKRFNRAQQVLEQALDHQ-PTCALAAMMNDVKALRVLVKVLRARD-ESALDVIQKMHDLQLRVIIRVSSEHQAELEEQKKLLSSICCDWAQEFHLRHELEKAKRHYTDALNHRPDDQQVLLHLAALYYEQQKLDYCEELCVKILQLQQEHTAAAMLFADTLYWKNQKEEAVKIYTSIMKRNPDNFHAMAKFLQILRRMGKLEDAVSVFNACEKFNPLTLREAGYQYCKGLYLWHSHQTSSSLTHLNKARGDADWGKPALEMMIHICLNPDKIIFGGEILDKGLRENISESENEMRMN---TAHNLLRMFHPRCRSEQDKAALLLNECRIYSRKHTQVETAVLELADTLANNVMLEECLLLMAEGFVQLKQIPRARNFLKRLTRMNWSDTNADYMEKGCLLLADMYIKMGKYTEGRTLLHRCTQHNKSCSKAYEYEGFMLENEQRYRDAALQYELAWRHSRQ--PAVGYRLALNYLKSQNYTLAVDVCRQVLQQHPDYPQINTEILTRARLSLRL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.:*.: :. **** :*:*::*. ::* .*: :. **.*:**:*:. * * : ::*:.:* :: **. ***:.:**: *** *: :* :*::**: .**. :.. *****.*: *:: : **: :.:***:* *. :::**: ***. . ::*.*::.* :*: :::***** :** :** * **:: :*: : .* ***::**::*:* **::** : .:*:**:* .::.* *:*:* :.::* .*: . :: : *:.*** ** **.**:: .:*** :**: :::***:** ::** .**: *::::*:* : .. . : .*:* .::*:* ****:**: ***:*:::*:: * * *** ::*:*:***.*::.:.* *: :*:.* *.:..* :*:**** ***. .* :*:* ** *: *:***.*:*:**.**:*.* :**:* .:*:*. * ..:*..:**:* **:*:* :*: ***:* : .. * .*. :*.:******: ::*::**:***::: . :.:::::**.* :*.** :::. * .::.:: *** *:: **. *: : *::: :*** : .:.. :: :.* : *.*.: : * *.:*:*.** ** :** **: *. :*: :* * *::::** :: ::: * *:::* .:::: **** .: *::::*** ****: :.*: .:*... . *.*::**:*:* ** *...:* .***** *: **: * *::******: :.*** ::. :. ..:* . : **.:*** *:*:. * * : ** . * : :*:::::*.*: : : : .** :*:.:: ***:*:** ****:: * :*: :**. *****:* : .*: . **:** *:**** :**** **::*:** *:**. :*:***::*:: **:*::**:****.:::. *:::*..** ::*.**:*. *** :*: *** ", "identical_positions": 392, "similar_positions": 405, "identity": "29.63%" }, { "cls_id": "homologset.agr.RGD:1308807", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZHA0-1", "uniprot_id": "FLNC_RAT", "id": "D3ZHA0-1", "name": "Filamin-C", "aln": "MMNNSNYSDASG--------LGLLDEADEMPSTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQKRMYRKFHPRPNFRQMKLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWEDEDDE--DARKQTPKQRLLGWIQNKVPQLPITNFNRDWQDGKALGALVDNCAPGLCPDWEAWDPNQPVQNAREAMQQADDWLGVPQVIAPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPVRSKQLNPKKAIAYGPGIEPQGNTVLQPAHFTVQTVDAGVGEVLVYIEDPEGHTEEAKVVPNNDKDRTYAVSYVPKVAGLHKVTVLFAGQNIERSPFEVNVGMALGDANKVSARGPGLEPVGNVANKPTYFDIYTAGAGTGDVAVVIVDPQGRRDTVEVALEDKGDNTFRCTYRPVMEGPHTVHVAFAGAPITRSPFPVHVAEA-----------------------------------------CNPNACRASGRGLQPKGVRVKEVADFKVFTKGAGSGELKVTVKGPKGTEEPVKVREAGDGVFECEYYPVIPGKYVVTITWGGYAIPRSPFEVQVSPEAGAQKVRAWGPGLETGQVGKSADFVVEAIGTEVGTLGFSIEGPSQAKIECDDRGDGSCDVRYWPTEPGEYAVHVICDDEDIRDSPFIAHIQPAPPDCFPDKVKAFGPGLEPTGCIVDRPAEFTIDARAAGKGDLKLYAQDADGCPIDIKVIPNGDGTFRCSYVPTKPIKHTVIISWGGVNVPKSPFRVNVGEGSHPERVKVYGPGVEKTGLKANEPTYFTVDCSEAGQGDVSIGIKCAPGVVGPAEADIDFDIIKNDNDTFTVKYTPPGAGHYTIMVLFANQEIPASPFHIKVDPSHDASKVKAEGPGLSRTGVEVGKPTHFTVLTKGAGKAKLDVHFAGAAKGEAVRDFEIIDNHDYSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVVNVAPPLDLSKVKVQGLNSKVAVGEEQAFLVNTRGAGGQGQLDVRMTSPSRRPIPCKLEPGSGAEAQAVRYMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGLVGTPAPFSIDTKGAGTGGLGLTVEGPCEAKIECQDNGDGSCAVSYLPTEPGEYTINILFAEAHIPGSPFKATIQPVFDPSKVRASGPGLERGKAGEAATFTVDCSEAGEAELTIEILSDA-GVKAEVLIHNNADGTYHITYSPAFPGTYTITIKYGGHPIPKFPTRVHVQPAVDTSGIKVSGPGVEPHGVLREVTTEFTVDARSLTATGGNHVTARVLNPSGAKTDTYVTD-NGDGTYRVQYTAYEEGVHLVEVLYDEVAVPKSPFRVGVTEGCDPTRVRAFGPGLEGGLVNKANRFTVETRGAGTGGLGLAIEGPSEAKMSCKDNKDGSCTVEYVPFTPGDYDVNITFGGQPIPGSPFRVPVKDVVDPGKVKCSGPGLGTG-VRARVPQTFTVDCSQAGRAPLQVAVLGPTGVAEP-VEVRDNGDGTHTVHYTPATDG-PYTVAVKYADQEVPRSPFKIKVLPAHDASKVRASGPGLNASGIPASLPVEFTIDARDAGEGLLTVQILDPEGKPKKANIRDNGDGTYTVSYLPDMSGRYTITIKYGGDEIPYSPFRIHALPTGDASKCLVTVSIGGHGLGACLGPRIQIG-EETVITVDAKAAGKGKVTCTVSTPDG-AELDVDVVENHDGTFDIYYTAPEPGKYVITIRFGGEHIPNSPFHVLACDPLPHVEEPAEVLQLHQPYAPLRPGTCPTHWATEEPVVPVEPLESMLRPFNLVIPFTVQKGELTGEVRMPSGKTARPNITDNKDGTITVRYAPTEKGLHQMGIKYDGNHIPGSPLQFYVDAINSGHVSAYGPGLSHGMVNKPATFTIVTKDAGEGGLSLAVEGPSKAEITCKDNKDGTCTVSYLPTAPGDYSIIVRFDDKHIPGSPFTAKITGDDSMRTSQLNVGTSTDVSLK--ITEGDLSQLTASIRAPSGNEEPCLLKRLPNRHIGISFTPKEVGEHVVSVRKSGKHVTNSPFKILVGPSEIGDASKVRVWGKGLSEGQTFQVAEFIVDTRNAGYGGLGLSIEGPSKVDINCEDMEDGTCKVTYCPTEPGTYIINIKFADKHVPGSPFTVKVTGEG--RMKESITRRRQAPSIATIGSTCDLNLKIPGNWFQMVSAQERLTRTFTRSSHTYTRTERTEISKTRGGETKREVRVEESTQVGGDPFPAVFGDFLGRERLGSFGS-ITRQQEGEASSQDMTAQVTSPSGKTEAAEIVEGEDSAYSVRFVPQEMGPHTVAVKYRGQHVPGSPFQFTVGPLGEGGAHKVRAGGTGLERGVAGVPAEFSIWTREAGAGGLSIAVEGPSKAEIAFEDRKDGSCGVSYVVQEPGDYEVSIKFNDEHIPDSPFVVPVASLSDDARRLTVTSLQETGLKVNQPASFAVQLNGARGVIDARVHTPSGAVEECYVSELDSDKHTIRFIPHENGVHSIDVKFNGAHIPGSPFKIRVGEQSQAGDPGLVSAYGPGLEGGTTGVSSEFIVNTQNAGSGALSVTIDGPSKVQLDCRECPEGHVVTYTPMAPGNYLIAIKYGGPQHIVGSPFKAKVTGPRLSGGHSLHETSTVLVETVTKSSSSRGASYSSIPKFSSDASKVVTRGPGLSQAFVGQKNSFTVDCSKAGTNMMMVGVHGPKTPCEEVYVKHMGNRVYNVTYTVKEKGDYILIVKWGDESVPGSPFKVNVP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VHX6-1", "uniprot_id": "FLNC_MOUSE", "id": "Q8VHX6-1", "name": "Filamin-C", "aln": "MMNNSNYSDASG--------LGLVDEADEMPSTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQKRMYRKFHPRPNFRQMKLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWEDEDDE--DARKQTPKQRLLGWIQNKVPQLPITNFNRDWQDGKALGALVDNCAPGLCPDWEAWDPNQPVQNAREAMQQADDWLGVPQVIAPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPVRSKQLNPKKAIAYGPGIEPQGNTVLQPAHFTVQTVDAGVGEVLVYIEDPEGHTEEAKVVPNNDKDRTYAVSYVPKVAGLHKVTVLFAGQNIERSPFEVNVGMALGDANKVSARGPGLEPVGNVANKPTYFDIYTAGAGTGDVAVVIVDPQGRRDTVEVALEDKGDNTFRCTYRPVMEGPHTVHVAFAGAPITRSPFPVHVAEA-----------------------------------------CNPNACRASGRGLQPKGVRVKEVADFKVFTKGAGSGELKVTVKGPKGTEEPVKVREAGDGVFECEYYPVVPGKYVVTITWGGYAIPRSPFEVQVSPEAGAQKVRAWGPGLETGQVGKSADFVVEAIGTEVGTLGFSIEGPSQAKIECDDKGDGSCDVRYWPTEPGEYAVHVICDDEDIRDSPFIAHIQPAPPDCFPDKVKAFGPGLEPTGCIVDRPAEFTIDARAAGKGDLKLYAQDADGCPIDIKVIPNGDGTFRCSYVPTKPIKHTIIVSWGGVNVPKSPFRVNVGEGSHPERVKVYGPGVEKTGLKANEPTYFTVDCSEAGQGDVSIGIKCAPGVVGPVEADIDFDIIKNDNDTFTVKYTPPGAGHYTIMVLFANQEIPASPFHIKVDPSHDASKVKAEGPGLSRTGVEVGKPTHFTVLTKGAGKAKLDVHFAGAAKGEAVRDFEIIDNHDYSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVVNVAPPLDLSKVKVQGLNSKVAVGQEQAFSVNTRGAGGQGQLDVRMTSPSRRPIPCKLEPGGGAEAQAVRYMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGLVGTPAPFSIDTKGAGTGGLGLTVEGPCEAKIECQDNGDGSCAVSYLPTEPGEYTINILFAEAHIPGSPFKATIQPVFDPSKVRASGPGLERGKAGEAATFTVDCSEAGEAELTIEILSDA-GVKAEVLIQNNADGTYHITYSPAFPGTYTITIKYGGHPIPKFPTRVHVQPAVDTSGIKVSGPGVEPHGVLREVTTEFTVDARSLTATGGNHVTARVLNPSGAKTDTYVTD-NGDGTYRVQYTAYEEGVHLVEVLYDEVAVPKSPFRVGVTEGCDPTRVRAFGPGLEGGLVNKANRFTVETRGAGTGGLGLAIEGPSEAKMSCKDNKDGSCTVEYIPFTPGDYDVNITFGGQPIPGSPFRVPVKDVVDPGKVKCSGPGLGTG-VRARVPQTFTVDCSQAGRAPLQVAVLGPTGVAEP-VEVRDNGDGTHTVHYTPATDG-PYTVAVKYADQEVPRSPFKIKVLPSHDASKVRASGPGLNASGIPASLPVEFTIDARDAGQGLLTVQILDPEGKPKKANIRDNGDGTYTVSYLPDMSGRYTITIKYGGDEIPYSPFRIHALPTGDASKCLVTVSIGGHGLGACLGPRIQIG-EETVITVDAKAAGKGKVTCTVSTPDG-AELDVDVVENHDGTFDIYYTAPEPGKYVITIRFGGEHIPNSPFHVLACDPLPHVEEPAEMLQMRQPYAPLRPGTCPTHWATEEPVVPVEPLESMLRPFNLVIPFTVQKGELTGEVRMPSGKTARPNITDNKDGTITVRYAPTEKGLHQMGIKYDGNHIPGSPLQFYVDAINSRHVSAYGPGLSHGMVNKPATFTIVTKDAGEGGLSLAVEGPSKAEITCKDNKDGTCTVSYLPTAPGDYSIIVRFDDKHIPGSPFTAKITGDDSMRTSQLNVGTSTDVSLK--ITEGDLSQLTASIRAPSGNEEPCLLKRLPNRHIGISFTPKEVGEHVVSVRKSGKHVTNSPFKILVGPSEIGDASKVRVWGKGLSEGQTFQVAEFIVDTRNAGYGGLGLSIEGPSKVDINCEDMEDGTCKVTYCPTEPGTYIINIKFADKHVPGSPFTVKVTGEG--RMKESITRRRQAPSIATIGSTCDLNLKIPGNWFQMVSAQERLTRTFTRSSHTYTRTERTEISKTRGGETKREVRVEESTQVGGDPFPAVFGDFLGRERLGSFGS-ITRQQEGEASSQDMTAQVTSPSGKTEAAEIVEGEDSAYSVRFVPQEMGPHTVTVKYRGQHVPGSPFQFTVGPLGEGGAHKVRAGGTGLERGVAGVPAEFSIWTREAGAGGLSIAVEGPSKAEIAFEDRKDGSCGVSYVVQEPGDYEVSIKFNDEHIPDSPFVVPVASLSDDARRLTVTSLQETGLKVNQPASFAVQLNGARGVIDARVHTPSGAVEECYVSELDSDKHTIRFIPHENGVHSIDVKFNGAHIPGSPFKIRVGEQSQAGDPGLVSAYGPGLEGGTTGVSSEFIVNTQNAGSGALSVTIDGPSKVQLDCRECPEGHVVTYTPMAPGNYLIAIKYGGPQHIVGSPFKAKVTGPRLSGGHSLHETSTVLVETVTKSSSSRGASYSSIPKFSSDASKVVTRGPGLSQAFVGQKNSFTVDCSKAGTNMMMVGVHGPKTPCEEVYVKHMGNRVYNVTYTVKEKGDYILIVKWGDESVPGSPFKVNVP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14315-1", "uniprot_id": "FLNC_HUMAN", "id": "Q14315-1", "name": "Filamin-C", "aln": "MMNNSGYSDAG---------LGLGDETDEMPSTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQKRMYRKFHPRPNFRQMKLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWEDEDDE--DARKQTPKQRLLGWIQNKVPQLPITNFNRDWQDGKALGALVDNCAPGLCPDWEAWDPNQPVENAREAMQQADDWLGVPQVIAPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPVRSKQLNPKKAIAYGPGIEPQGNTVLQPAHFTVQTVDAGVGEVLVYIEDPEGHTEEAKVVPNNDKDRTYAVSYVPKVAGLHKVTVLFAGQNIERSPFEVNVGMALGDANKVSARGPGLEPVGNVANKPTYFDIYTAGAGTGDVAVVIVDPQGRRDTVEVALEDKGDSTFRCTYRPAMEGPHTVHVAFAGAPITRSPFPVHVSEA-----------------------------------------CNPNACRASGRGLQPKGVRVKEVADFKVFTKGAGSGELKVTVKGPKGTEEPVKVREAGDGVFECEYYPVVPGKYVVTITWGGYAIPRSPFEVQVSPEAGVQKVRAWGPGLETGQVGKSADFVVEAIGTEVGTLGFSIEGPSQAKIECDDKGDGSCDVRYWPTEPGEYAVHVICDDEDIRDSPFIAHILPAPPDCFPDKVKAFGPGLEPTGCIVDKPAEFTIDARAAGKGDLKLYAQDADGCPIDIKVIPNGDGTFRCSYVPTKPIKHTIIISWGGVNVPKSPFRVNVGEGSHPERVKVYGPGVEKTGLKANEPTYFTVDCSEAGQGDVSIGIKCAPGVVGPAEADIDFDIIKNDNDTFTVKYTPPGAGRYTIMVLFANQEIPASPFHIKVDPSHDASKVKAEGPGLNRTGVEVGKPTHFTVLTKGAGKAKLDVQFAGTAKGEVVRDFEIIDNHDYSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVVNVAPPLDLSKIKVQGLNSKVAVGQEQAFSVNTRGAGGQGQLDVRMTSPSRRPIPCKLEPGGGAEAQAVRYMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGLVGTPAPFSIDTKGAGTGGLGLTVEGPCEAKIECQDNGDGSCAVSYLPTEPGEYTINILFAEAHIPGSPFKATIRPVFDPSKVRASGPGLERGKVGEAATFTVDCSEAGEAELTIEILSDA-GVKAEVLIHNNADGTYHITYSPAFPGTYTITIKYGGHPVPKFPTRVHVQPAVDTSGVKVSGPGVEPHGVLREVTTEFTVDARSLTATGGNHVTARVLNPSGAKTDTYVTD-NGDGTYRVQYTAYEEGVHLVEVLYDEVAVPKSPFRVGVTEGCDPTRVRAFGPGLEGGLVNKANRFTVETRGAGTGGLGLAIEGPSEAKMSCKDNKDGSCTVEYIPFTPGDYDVNITFGGRPIPGSPFRVPVKDVVDPGKVKCSGPGLGAG-VRARVPQTFTVDCSQAGRAPLQVAVLGPTGVAEP-VEVRDNGDGTHTVHYTPATDG-PYTVAVKYADQEVPRSPFKIKVLPAHDASKVRASGPGLNASGIPASLPVEFTIDARDAGEGLLTVQILDPEGKPKKANIRDNGDGTYTVSYLPDMSGRYTITIKYGGDEIPYSPFRIHALPTGDASKCLVTVSIGGHGLGACLGPRIQIG-QETVITVDAKAAGEGKVTCTVSTPDG-AELDVDVVENHDGTFDIYYTAPEPGKYVITIRFGGEHIPNSPFHVLACDPLPHEEEPSEVPQLRQPYAPPRPGARPTHWATEEPVVPVEPMESMLRPFNLVIPFAVQKGELTGEVRMPSGKTARPNITDNKDGTITVRYAPTEKGLHQMGIKYDGNHIPGSPLQFYVDAINSRHVSAYGPGLSHGMVNKPATFTIVTKDAGEGGLSLAVEGPSKAEITCKDNKDGTCTVSYLPTAPGDYSIIVRFDDKHIPGSPFTAKITGDDSMRTSQLNVGTSTDVSLK--ITESDLSQLTASIRAPSGNEEPCLLKRLPNRHIGISFTPKEVGEHVVSVRKSGKHVTNSPFKILVGPSEIGDASKVRVWGKGLSEGHTFQVAEFIVDTRNAGYGGLGLSIEGPSKVDINCEDMEDGTCKVTYCPTEPGTYIINIKFADKHVPGSPFTVKVTGEG--RMKESITRRRQAPSIATIGSTCDLNLKIPGNWFQMVSAQERLTRTFTRSSHTYTRTERTEISKTRGGETKREVRVEESTQVGGDPFPAVFGDFLGRERLGSFGS-ITRQQEGEASSQDMTAQVTSPSGKVEAAEIVEGEDSAYSVRFVPQEMGPHTVAVKYRGQHVPGSPFQFTVGPLGEGGAHKVRAGGTGLERGVAGVPAEFSIWTREAGAGGLSIAVEGPSKAEIAFEDRKDGSCGVSYVVQEPGDYEVSIKFNDEHIPDSPFVVPVASLSDDARRLTVTSLQETGLKVNQPASFAVQLNGARGVIDARVHTPSGAVEECYVSELDSDKHTIRFIPHENGVHSIDVKFNGAHIPGSPFKIRVGEQSQAGDPGLVSAYGPGLEGGTTGVSSEFIVNTLNAGSGALSVTIDGPSKVQLDCRECPEGHVVTYTPMAPGNYLIAIKYGGPQHIVGSPFKAKVTGPRLSGGHSLHETSTVLVETVTKSSSSRGSSYSSIPKFSSDASKVVTRGPGLSQAFVGQKNSFTVDCSKAGTNMMMVGVHGPKTPCEEVYVKHMGNRVYNVTYTVKEKGDYILIVKWGDESVPGSPFKVKVP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PHR9-1", "uniprot_id": "A0A8M9PHR9_DANRE", "id": "A0A8M9PHR9-1", "name": "", "aln": "MMSNNTYYDQQLPPQYYQGTDNGEDGDEEMPATEKDLAEDAPWKKIQQNTFTRWCNEHLKCLNRKILDLQKDLTDGLKLIGLLEVLSQKKMYRKYHARPNFRQMKLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWEDEDDE--DARKLTPKQRLLGWIQNKVPQLHINNFHRDWRDGKALGALVDNCAPGLCPDWETWDPSQPVENAREAMQQADDWLGVPQVIAPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRPKTLHPKRAKAYGPGIEPRGNVVLKPAEFVVETVEAGLGEVLVYIEDPEGHTEEARVIPNNDRNRSYSVVYVPKVEGLHKVKVLFAGQDIDRSPFLVNVSKALGDPNKVQARGPGLEPVGNVANKPTYFDIYTAGAGAGDVGVIIVDSQGRRDTVEIILENKGDSVFRCTYGPILEGPHTIYVTFAGQQIPRSPFTVHISEAPPHGRQIGSPVHIIPQSLRTPPSEKAKKVPPPTPPKPRRPTSNPNACRAIGRGLQPKGVRVKEVADFKVYTKGAGSGELRVHVKGPTGGDEPVKVEDLGDGVYECDYYPIFCGKYIITVTWGGHAIPRSPFEVIISEDAGPQKVRAWGPGLETGMVGKSADFVVEAIGTEVGTLGFSIEGPSQAKIECDDKGDGSCDVLYWPTEPGDYAVHVICDDEDIKDSPFMAHILPAASDVFPEKVKCYGPGLEPTGCIVNKPAEFTIDARGAGRGQLQIYAQDSEGFPINIQITDNGDSTYFCVYIPIKPIKHTIIITWGEVNVPNSPFRVTIGEGSHPENVKVHGPGVEKTGLKANEPTYFTVDCSEAGQGDVSIGIKCAPGVVGPAEADIDFDIIKNDNDTFTVKYTPPGAGRYTIMVLFADQEIPISPFRIKVDPSHDANKVKAEGPGLNKTGVEVGKPTHFTIYTKGAGKATPEVHFTASGRGDAVSDFEIIDNHDYSFTVRYTALQQGNMTISVCHGGDPIPKSPFTISVAPPLDLNKVKVHGLNNKVDVGKDEEFTVNTRGAGGQGKVDVKITSPSRRPIPCKVESGASNEVHTVKYIPPEEGPYKVDISYDGNPVPGSPFTVEGVMPPDPSKVRAYGPGLKGGIVGKPAPFAIDTKGAGTGGLGLTVEGPCEAKIECQDNGDGSCSVSYLPTEPGEYSINILFADAHIPGSPFKAMVQSVFDPSKVTASGPGLERGKVNEAGSFTVDCSKAGEAELTIEIISDS-GAQAEVHVQNNSDGTYSITYIPPFHGMYTITIKYGGHAVPKFPARVQVDPALDTSGIKVYGPGVEPRGVLREVTTHFIVDTRVHNKMGGNHIKVRIVNPSGANTDAYVTD-KADGTYRVEYTAYEDGVHLIEVLYDDVPVPKSPFRVAVAEGCDPSRVRAYGPGLEEGLVNKPNRFTVETRGAGTGGLGLAIEGPSEAKMSCKDNKDGSCSVEYIPFTPGEYDVNITFGGLPIPGSPFRVPVRELVDPSKVKCTGPGLGSG-VRAHVPQTFTVDCSKAGLAPLEVLLYGPTGMTEP-VNITDNGDGTHTVVYTPAKDG-PYTVCVKYADQEVPRSPFKIKVLPAHDASKVRASGPGLNASGVPASLPVEFTIDARDAGEGLLTVQILDPEGKPKKANIRDNRDGTYTVSYVPDMTGRYTITIKYGGDEIPYSPYRIHALPSGDASKCLVTVSIGGHGLGSGLGPTIQIG-EETVITVDAKAAGKGKVTCKVSTPDG-AELDVDVVENADGTFDIYYTAPEPGKYVITIRFGGEHIPNSPFHVVASDTIPIIEEPCDKLQLQQPYAPYQG--YSPHWATEEPVTAVDIIEPVLRPFNLVIPFTVQKGEITGEVHMPSGKTASPHITDNKDGTVTVKYAPTEKGLHEMDIKYDGNHIPGSPLQFYVDAINSGHVNAYGPGLSHGMVNKSATFTIVTKDAGEGGLSLAVEGPSKAEISCKDNKDGTCTVSYLPTAPGDYNIIVKFDDKHIAGSPFTAKITGDDSMRTSQLNVGTATDVSLK--ITETDLSSLSATIRAPSGNEEPCLLKRLPNRHIGISFTPKEVGEHVVSVKKNGKHVTNSPFKIMVGQSEIGDASKVKVSGKGLIEGHTFEVAEFIVDTRSAGYGGLGLSIEGPSKVDINCSDVDDGTCKVTYCPTEPGTYIINIKFADQHVPGSPFTVKVLGEG--RMKESITRKRQAPSIATVGSTCDLNLKIPGNWFQMVSAQERLTRTFTRSSHTYTRTERTEISKTRAGETKREVRVEESTQVGGDPFRDVFGGFMGRESLGPFNSPQGRQSEGESGTQEMTAQVTSPSGNTEDAEIIEGEDSTYSVRFVPHEMGPHTVNVKYRGQHVPGSPFQFTVGPLGEGGAHKVRAGGTGLDRGVAGVPAEFSIWTREAGAGGLSIAVEGPSKAEISFEDRKDGSCGVAYIVQEPGDYEVSIKFNDEHIPDSPFIVPIASLSDDARLLTVTSLQEMGLKVNQEASFAVQLNGARGAIDAKVHTPSGAVEECYITELDNDKHAIRFIPRENGVHSIDVRFNGSHIPGSPFKIRVGEPGQAGDPGMVTAFGPGLEGGTTGVPSDFIVNTCNAGSGALSVTIDGPSKVKMDCQECPEGYKVTYTPMAPGSYLISIKYGGPQHIVGSPFKAKVSGARLSGGHSLHETSSVLVETVTKSSSVAG-SFSTLPKFSSDASKVVSRGAGLSKAFIGQKNTFTVDCSKAGTNMLMVGVHGPKTPCEEVYVKHMGNRMYNVTYTVKEKGDYILIVKWGEEMVPGSPFHVTVP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VEN1-1", "uniprot_id": "FLNA_DROME", "id": "Q9VEN1-1", "name": "Filamin-A", "aln": "------------------------------MEAERDLAEDAQWKKIQQNTFTRWANEHLKTIDRSINNLETDLSDGLRLIALIEVLSQKRMP-KYNKRPTFRSQKLENVSVALKFLQDEGIKIVNIDSSDIVDCKLKLILGLIWTLILHYSISMPMWDGEDDKQLNGSGHTPKQRLLNWIHAKIPDLPINNFTNDWTTGKAVGALVDACAPGLCPDWELWDPKDAVQNASEAMGLADDWLNVRQLIKPEELVNPNVDEQSMMTYLSQYPNSKLKTGAPLRPK-TNPNRVRAYGPGIEPIGPVVGAPANFTVETFSAGKGSVDVDIQGPNGEIEKADVRFNNDKNLTYTVSYIPKSEGSHKVAVKFSGRDIPKSPFPVKVEGHAGDASKVKVTGPGIQPNGVTIKKPTFFDILAKDAGRGVPEVIIIDPANHKTSVAAKVRQLENDTWRCEYVTALQGLHSVNVFYAGTPIPNSPFPVKVAPL-----------------------------------------SDARKVRASGRGLQATGVRVGDDADFKIYTEGAGEGEPEVRVIGPGGMNQNVMQSKVDGNTYECHYYPTKEGRYVIMVTFAGQEVAKSPFEVKVGPKK-ESSIVAYGPGLSSGVIGYPAAFVVETNG-ETGALGFTVAGPSQAEIECHDNGDGSALVKYHPTAVGEYAVHILCDNEDIPKSPFIAQILPR-TDFHPELVKASGPGLEKNGVTINQPTSFTVDPSKAGNAPLDVVVQDVFGTKLPVELKNNPDGTKKVTYTPTSGVPHTVEVNYGGVSTPNSPHRVYVG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VPVDAAKVQAFGPWLQPGVR--------------------------------------------------------------------------------------------PNAATHFNVDAREAGDAELKVKIIHEETKIEVPCRIIDNEDNTYSVEVIPPSKGAYTTTMTYGGQRVP-LGEKVVVEQTVDVSKIKVDG--LEPSVIMNAATDFMVDMSKVGSNIDSGKLSCAIFDPMGHVLPSKIVQGPTDDIFRIMYTPFEAGRHTIELMYDNIPVPGSPFVVNVKSGCDPARCKAYGPGLEKGLTNQKNKFTVETKGAGNGGLSLAIEGPSEAKMTCTDNRDGSCDVDYLATDPGEYDITIRFADKHIPGSPFRVLVEETVDPSKVKVYGPGIEHGQVRESVPTFFNVDVGEAGPGRIAVKLTNSEGIPVDNLRVEDKGNCIYAVHYVPPKAGSVLTCQVKFSEVEVPCSPFVMTVFPKSEPTKVKVKGVNEKKK-TPASLPAEFEIDTKQAGQADINVAIKNPKGKAMQPRLEEVSTGTYVVSFVPDECGTYQCSIKYGDKEIEGSPFKLEAFPTGEAKKCKLVEQA----------PKIQTSGSQSHLKVDAREAGDGAVTCKITNKAGSEIVDIDVIE-KDGFFDILYALNDPGDYDINVKFGGKDIPNGSFSIKAVESIEQYSHSEYIEEHTTKVVQQTTQSELVNGKSEITYRSVAFEK---------LPLPTTGGNVTAEVRMPSGKVDKPVIQDNRDGTVSVKYDPREEGSHELVVKYNGEPVQGSPFKFHVDSITSGYVTAYGPGLTHGVTGEPANFTISTKGASAGGLTMAVEGPSKADINYHDNKDGTVSVQYLPTAPGEYQVSVRFGDKHIKGSPYFAKITGEGRKRN-QISVGSCSEVTMPGDITDDDLRALNASIQAPSGLEEPCFLKRMPTGNIGISFTPREIGEHLVSVKRLGKHINNSPFKVTVCEREVGDAKKVKVSGTGLKEGQTHADNIFSVDTRNAGFGGLSVSIEGPSKAEIQCTDKDDGTLNISYKPTEPGYYIVNLKFADHHVEGSPFTVKVAGEGSNRKREKIQRERDAVPITEIGSQCKLTFKMPG-----------------------------------------------------------------------------------ITSFDLAACVTSPSNVTEDAEIQEVEDGLYAVHFVPKELGVHTVSVRYSEMHIPGSPFQFTVGPLRDSGSHLVKAGGSGLERGVVGEAAEFNVWTREAGGGSLAISVEGPSKADIEFKDRKDGSCDVSYKVTEPGEYRVGLKFNDRHIPDSPFKVYVSPDAGDAHKLEVQQFPQGNIQADAPYQFMVRKNGAKGELDAKIVAPSGTDDDCFIQVIDGEMYSVRFYPRENGIHAIHVKFNGVHIPDSPFRIKVG--KDVADPAAVHASGNGLDEVKTGHKADFIINTCNAGVGTLAVSIDGPSKVAMDCTEVEEGYKVRYTPLLPGEHYITVKYNN-MHIVGSPFKVNATGDKLAD-EGAQETSTVIVETVQKVAKGGKNTGVHLPTFKSDASKVVSKGMGLKKAYIGKQNQFSISATDAGNNILYVGMYGPKGPCEEFHVKHAGHNNYNVQYLVRDRGQYVLLIKWGEEHIPGSPFQIDV-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*:****** ************.***** :.: : :*: **:***:**.*:******:* *:: **.**. *********:**: * **:*.***. *** :**********************:.***: :. *******.**: *:*:* *.** .** ***:***** ********** ***.:.*:** *** *****.* *:* ***:*:*****:*:******:*::***.***:*.* :*::. ******** * .* **.*.*:*..** *.* * *:.*:*. *:* * ***:: :*:* *:** * *** * *:*::* :*** *:* **..**.. ***::* * . :***:*** : .** * *:*:*. .:: :* :.: :..:** * . ::* *:: * :** *..***.*::: .:.. ** *****..**** : ****::*:***.** .* * ** * :: * . ....:**.*** *:*:: :*:.* :.:***** :. . ..: *:****.:* :* .* ****: * *.*:***:: *****:***.*.****. * * ** *:****::**:*** .***:*:* * .* .*: **. ***** .* :::*:.**:*. **.. *.: .** * : ::: * *.* * * . : **: :.:* *..*:**.** :* :* *.:** *:** *: *: . * *.**. :**:***.::*: : :. : :* *.** : *. * ** *:.***: :* : :* *: ::*.* :** * :** ::. .* : :: . ...::. :.:* * : :.: *. :*: **.:* * * :*::**::.** *** * * .****:* :*:***** **.*: *:*****:***.***.***********:*.**:**** *:*:. **:**:.* *.. ******** *.: ***.*** ***: * ** ** *.** .:** . : * : .. *:. :.: *:*: ::* *.*.. * * **::: *** *** :.*:* :.:**:..* . : . *****.** **:::**:. :.* * :*:**. :..:.: ***.**::** * * :****..** **:::.*:*:*:*.** :. . * ** . .:: :.***: **.* ***.::. * :*:**:* ** *** *: :**.* *.::***:.***..* : * :.: ... : . : :* . .* : :*:.. *::*.**:*****. * * **:***::*:* * *:* *:: :**:*: : ***::*:**:*.* :*.******:**:..:.*.*** **.*. ***::********:*. :****** :*.*******:*.: *:*.**** ***: *****:. *. *:.**:.::*:: **: ** *.*:*:**** ****:***:*. :*******:*:***:***:: ***:.*****: * *:***.**:* *.** **:*. * ****.**:***.:*******.:*:* * :*** :::* ***** **:*:****:** ******** *** * :*.* *.*:* .*: :** *.*.:*:** : :::* *****. .* *** * **. *:*:***:*:* *** *:* *:************ :.*:* *:***:**:***.* .***.:******.*.*:*:*******:* *:*******.*:* * ***:*.*.:****.******* * ::. :.**: * * .: : .::.: .* *: ***:* :**:: :***: ::*:: :*.: :::** *:***:*:*.*:*** ***.***:*:** :..**. * * * **: .** ::**:** *** *:*:*:******* :** * **: * ***: **.: *::**.. ********.:.:* :*:. .. :***:*:**** * :. : :*.*.*******::* **.:*::*::* *::..:.**.*:: **::*** ****.:*** *:. *** * *:::*:*:*::***:* :*****:: * ", "identical_positions": 1076, "similar_positions": 661, "identity": "38.58%" }, { "cls_id": "homologset.agr.RGD:1308808", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q80TL7-1", "uniprot_id": "MON2_MOUSE", "id": "Q80TL7-1", "name": "Protein MON2 homolog", "aln": "----MSCTNSPEAVKKLLENMQSDLRALSLECKKKFPPVKEAAESGIIKVKTIAARNTEILAALKENSSEVVQPFLMGCGTKEPKITQLCLAAIQRLMSHEVVSETAAGNIINMLWQLMENSLE-ELKLLQTVLVLLTTNTVVHDEALSKAIVLCFR--LHFT-KDNITNNTAAATVRQVVTVVFERMVAEDDRHRD-IEPPVPIQGNSNRRSVSTLRPCAKDAYMLFQDLCQLVNADAPYWLVGMTEMTRTFGLELLESVLNDFPQVFLQHQEFSFLLKERVCPLVIKLFSPNIKFRQGSSTS--SSPAPVEKPYFPICMRLLRVVSVLIKQFYSLLVTECEIFLSLLVKFLDSDK--PQWLRAVAVESIHRLCVQPQLLRSFCQSYDMKQHSTKVFRDIVNALGSFIQSLFLVPPTGN-PATANQAGNNNAGGPASAPANSGVVGVGGGVTLLPAFEYRGAWIPILTVTVQGSAKATYLEMLDKVEPPTIPEGYAMSVAFHCLLDLVRGITTMIEGELGEVEAEGPSVTEGASS--QSSERRDEQAASDPMDQETVSRAVWEEMVSACWCGLLAALSLLLDAS-TDEAATENILKAELTMAALCGRLGLVTSRDAFITAICKGSLPPHYALTVLNATTAATLSNKSYSIQGQ---SVMMISPSS----ESHQQVVAVGQPLAVQ------PQGTVMLTSKNIQCMRTLLNLAHCHGAVLG-TSWQLVLATLQHLVWILGLKPSSGGALKPG-RAVEGPSTVLTTAVMTDLPVISNILSRLFESSQYLDDVSLHHLINALCSLSLEAMDMAYGNNKEPSLFAVAKLLETGLVN---------------------MHRIEILWRPLTGHLLEKVCQHPNSR--MREWGAEALTSLIRAGLTFS-----HEPPLPQNQRLQLLLLNPLKEMSN-----------------INHPDIRLKQLECVLQILQSQGDSLGPGWPLVLGVMG------------AIRNDQGES------------LIRTAFQCLQLVVTDFLPTMPCSCLQIVVDVAGSFGLHNQELNISLTSIGLLWNISDYFFQRGETIEKELNKEEAAQQKQAEEKGVSLNRP----FHPAPPFDCLWLCLYAKLGELCVDPRPAVRKSAGQTLFSTIGAHGTLLQHSTWHTVIWKVLFHLLDRVRESSTTADKEKIESGGGNILIHHSRDTAEKQWAETWVLTLAGVARIFNTRRYLLQPLGDFSRAWDVLLDHIQSAALSKNNEVSLAALKSFQEILQIVSPVRDSEKPEPP-AVSVPVPVLLGNLSGPGLSRPFVRTDSIGEKLGRCGS-ETPVVT--DELEDLKLWWAAWNTWHRTGSESTEPPSS-VDELT-------------FIPSQPFLTALVQIFPALYQHIKAG--FSMADLQKLGVILHSAVSVPISSDASPFILP--SYTEAVLTSLQEAVLTALDVLQKAICVGPENMQIMYPAIFDQLLAFVEFSCKPPQYGQLETKHIANAKYNQIQLFAPAEWVALNYVPFAERSLEVVVDLYQKTACHKAVVNEKVLQNI-IKTLRVPLSLKYSCPSESTWKLAVASLLKVLSIGLPVARQHASSGKFDSMWPELASTLEDFLFTKSIP-PDNLSIQEFQRNESIDVEVVQLISAEILPYANLIPKAFVGQMMTMLNKGSIHSQPCSFTEAEIDIRLREEFSKMCFETLLQFSFSNKVTTPQ------------------EGYISRMALSVLLKRSQDVLHRYIEDERLSGKCPLPRQQVTEIIFVLKAVSTLIDSLKKTQPENVDGNTWSQVIALYPTLVECITCSSSDVGSALKEALAPFKDFMQPPASR----------VQNGES", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZCG3-1", "uniprot_id": "D3ZCG3_RAT", "id": "D3ZCG3-1", "name": "Protein MON2 homolog", "aln": "----MSCTNSPEAVKKLLENMQSDLRALSLECKKKFPPVKEAAESGIIKVKTIAARNTEILAALKENSSEVVQPFLMGCGTKEPKVTQLCLAAIQRLMSHEVVSEAAAGNIINMLWQLMENSLE-ELKLLQTVLVLLTTNTVVHDEALSKAIVLCFR--LHFT-KDNITNNTAAATVRQVVTVVFERMVAEDDRHRD-IDPPVLIQGNSNRRSVSTLRPCAKDAYMLFQDLCQLVNADAPYWLVGMTEMTRTFGLELLESVLNDFPQVFLQHQEFSFLLKERVCPLVIKLFSPNIKFRQGSGTS--SSPAPVEKPYFPICMRLLRVVSVLIKQFYSLLVTECEIFLSLLVKFLDADK--PQWLRAVAVESIHRLCVQPRLLRSFCQSYDMKQHSTKVFRDIVNALGSFIQSLFLVPPTGN-PAAANQAGNNNAGGPASAPANSGVVGIGAGVTLLPAFEYRGAWIPILTITVQGSAKATYLEMLDKVEPPTIPEGYAMSVAFHCLLDLVRGITTMIEGELGEVETECPTVTEGASS--QSSERRDEQSESDHMDQETVSRAVWEEMVSACWCGLLAALSLLLDAS-TDEAATENILKAELTMAALCGRLGLVTSRDAFITAICKGSLPPHYALTVLNATTAATLSNKSYSIQGQ---SVMMISPSS----ESHQQVVAVGQPLAVQ------PQGTVMLTSKNIQCMRTLLNLAHCHGAVLG-TSWQLVLATLQHLVWILGLKPSSGGALKPG-RAVEGPSTVLTTAVMTDLPVISNILSRLFESSQYLDDVSLHHLINALCSLSLEAMDMAYGNNKEPSLFAVAKLLETGLVN---------------------MHRIEILWRPLTGHLLEKVCQHPNSR--MREWGAEALTSLIKAGLTFN-----HEPPLSQNQRLQLLLLNPLKEMSN-----------------INHPDIRLKQLECVLQILQSQGDSLGPGWPLVLGVMG------------AIRNDQGES------------LIRTAFQCLQLVVTDFLPTMPCSCLQIVVDVAGSFGLHNQELNISLTSIGLLWNISDYFFQRGETIEKELNKEEAAQQKQAEEKGVSLNRP----FHPAPPFDCLWLCLYAKLGELCVDPRPAVRKSAGQTLFSTIGAHGTLLQHATWHTVIWKVLFHLLDRVRESSTTADKEKIESGGGNILIHHSRDTAEKQWAETWVLTLAGVARIFNTRRYLLQPLGDFSRAWDVLLDHIQSAALSKNNEVSLAALKSFQEILQIVSPARDSEKPETP-VGTVPVPVLIGNISGQGLSRPFVRTDSIGEKLGRCSS-EPPVVT--DEAEDLKLWWAAWNTWHRTGSESTEPPST-FDELT-------------FIPSQPFLTALIQIFPALYQHIKAG--FSMADLQKLGVILHSAVSVPISSDASPFILP--SYTEAVLTSLQEAVLTALDVLQKAICVGPENMQIMYPAIFEQLLAFVEFSCKPPQYGQLETKHIANAKHNQIQLFAPAEWVALNYVPFAERSLEVVVDLYQKTACHKAVVNEKVLQSI-IKTLRVPLSLKYSCPSESTWKLAVASLLKVLSIGLPVARQHASSGKFDSMWPELASTLEDFLFTKSIP-PDNLSIQEFQRNESIDVEVVQLISAEILPYANLIPKAFVAQMMTMLNRGSIHSQPSSFTEAEIDIRLREEFSKMCFETLLQFSFSNKVTTPQ------------------EGYISRMALSVLLKRSQDVLHRYIEDERLSGKCPLPRQQVTEIIFVLKAVSTLIDSLKKTQPENVDGNTWAQVIALYPTLVECITCSSSDVCSALKEALVPFKDFMQPPASK----------VQNGES", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7Z3U7-1", "uniprot_id": "MON2_HUMAN", "id": "Q7Z3U7-1", "name": "Protein MON2 homolog", "aln": "----MSGTSSPEAVKKLLENMQSDLRALSLECKKKFPPVKEAAESGIIKVKTIAARNTEILAALKENSSEVVQPFLMGCGTKEPKITQLCLAAIQRLMSHEVVSETAAGNIINMLWQLMENSLE-ELKLLQTVLVLLTTNTVVHDEALSKAIVLCFR--LHFT-KDNITNNTAAATVRQVVTVVFERMVAEDERHRDIIEQPVLVQGNSNRRSVSTLKPCAKDAYMLFQDLCQLVNADAPYWLVGMTEMTRTFGLELLESVLNDFPQVFLQHQEFSFLLKERVCPLVIKLFSPNIKFRQGSSTS--SSPAPVEKPYFPICMRLLRVVSVLIKQFYSLLVTECEIFLSLLVKFLDADK--PQWLRAVAVESIHRFCVQPQLLRSFCQSYDMKQHSTKVFRDIVNALGSFIQSLFLVPPTGN-PATSNQAGNNNLGGSVSAPANSGMVGIGGGVTLLPAFEYRGTWIPILTITVQGSAKATYLEMLDKVEPPTIPEGYAMSVAFHCLLDLVRGITSMIEGELGELETECQTTTEEGSSPTQSTEQQDLQSTSDQMDKEIVSRAVWEEMVNACWCGLLAALSLLLDAS-TDEAATENILKAELTMAALCGRLGLVTSRDAFITAICKGSLPPHYALTVLNTTTAATLSNKSYSVQGQ---SVMMISPSS----ESHQQVVAVGQPLAVQ------PQGTVMLTSKNIQCMRTLLNLAHCHGAVLG-TSWQLVLATLQHLVWILGLKPSSGGALKPG-RAVEGPSTVLTTAVMTDLPVISNILSRLFESSQYLDDVSLHHLINALCSLSLEAMDMAYGNNKEPSLFAVAKLLETGLVN---------------------MHRIEILWRPLTGHLLE-VCQHPNSR--MREWGAEALTSLIKAGLTFN-----HDPPLSQNQRLQLLLLNPLKEMSN-----------------INHPDIRLKQLECVLQILQSQGDSLGPGWPLVLGVMG------------AIRNDQGES------------LIRTAFQCLQLVVTDFLPTMPCTCLQIVVDVAGSFGLHNQELNISLTSIGLLWNISDYFFQRGETIEKELNKEEAAQQKQAEEKGVVLNRP----FHPAPPFDCLWLCLYAKLGELCVDPRPAVRKSAGQTLFSTIGAHGTLLQHSTWHTVIWKVLFHLLDRVRESSTTADKEKIESGGGNILIHHSRDTAEKQWAETWVLTLAGVARIFNTRRYLLQPLGDFSRAWDVLLDHIQSAALSKNNEVSLAALKSFQEILQIVSPVRDSDKPETPPVVNVPVPVLIGPISG--MSRPFVRTDSIGEKLGRYSSSEPPIVT--DELEDLNLWWAAWNTWYRIGSESTKPPIT-FDKLT-------------FIPSQPFLTALIQIFPALYQHIKTG--FNMDDLQKLGVILHSAISVPISSDASPFILP--SYTEAVLTSLQEAVLTALDVLQKAICVGPENMQIMYPAIFDQLLAFVEFSCKPPQYGQLETKHIANAKYNQIQLFAPAEWVALNYVPFAERSLEVVVDLYQKTACHKAVVNEKVLQNI-IKTLRVPLSLKYSCPSESTWKLAVSSLLRVLSIGLPVARQHASSGKFDSMWPELANTFEDFLFTKSIP-PDNLSIQEFQRNENIDVEVVQLISNEILPYANFIPKEFVGQIMTMLNKGSIHSQSSSFTEAEIDIRLREEFSKMCFETLLQFSFSNKVTTPQ------------------EGYISRMALSVLLKRSQDVLHRYIEDERLSGKCPLPRQQVTEIIFVLKAVSTLIDSLKKTQPENVDGNTWAQVIALYPTLVECITCSSSEVCSALKEALVPFKDFMQPPASR----------VQNGES", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9P6K6-1", "uniprot_id": "A0A8M9P6K6_DANRE", "id": "A0A8M9P6K6-1", "name": "Protein MON2 homolog", "aln": "-MSLKMSTSSPEAVKKLLENMQADLRSLSMECKKKFPPVKEAAESGIVKIKTIAARNTDILAALKENSSEVVQPFLMGCGTKEPKITQLCLAAIQRLMSHEVVSEAAAGNIINMLWQLMENGLE-ELKLLQTVLVLLTTNTIVHDEVLSKAIVLCFR--LHFT-KDNITNNTAAATVRQVVTVVFERMVAEDERFKGLNEEPPAVQGNCNRRSVSTLRPSAKDAYMLFQDLCQLVNADAPYWLVGMTEMTRTFGLELLESVLNDFPQVFLQHQEFSFLLKERVCPLVIKLFSPNIKFRQGSSSSS-ASPAPVEKPYFPICMRLLRVVSVLIKHFYSLLVTECEIFLSLLVKFLDGEK--PQWLRAVAVESVHRLCVQPHLLRSFCQSYDMKPHSTKVFRDIVNALGSFIQSLFILPSAGNTSSTSTPAGGSVSSSQASGPGGPGLTGAGGALTTQAAFEYRGTWIPLMNVSVQGSAKATYLEMLDKVEPPSIPEGYAMSVAFSALLDLVRGITNMIDRELLRQE--------------QQEAMREEEEPVSPPAQEPLAAEVWQEMVNACWCGLLAALSLLLDAS-TDETATENILKAELSMASLCGRLGLVTPRDAFITAVCKASLPPHYALTILSSS-ASSLTNKVYSIQGQ---SVQMVSPSS----ESHQQVVAVGQPLSAQ------PQGTVVLTAKNIQCMRTLLNLAHCHGAHLG-TSWQLVLATLQHLVWILGLKPAPGGVLKPG-RAVEGPSTVLTTAVMTDLPVISNILSRLFESSQYLDDVSLHHLINALCSLSMEAMEMAYGTNKEPSLFAVAKLLETGLVN---------------------MDRIEILWRPLTAHLLE-VCQHPNAR--MREWGAEAITSLIKAGLSYK-----HDPPLSQNQRLQLLLLNPLKELSN-----------------VLHADIRQKQLECVLQILQNQGDSLGPGWPLVLGVIG------------AIRNDQGES------------LIRTAFQCLQLVVTDFLPTMPCMCLQIVVDVAGSFGLQNQELNISLTSIGLLWNISDYFFQRGEAITEELDKEEAVLLKQAQDKGEPLNRP----FHPAPPFDCLWLCLYAKLGELCVDPRPAVRKSAGQTMFSTIAAHGTLLQPPTWNIVVWKVLFHLLDCVRKSSTTADKEKIESGGGNILIHHSRDTAEKQWAETWVLTLAGVARIFNTRRYLLQQLGDFFKAWEVLLDHIQSAALSKNNEVSLAALKSFQEILQLVTPIKDTDKPDALSAIDVPS-VLMESLQGSGPGRPLVRSDSLAERLAQRYAAQPSLPPPGEELDDSALWWSAWNTWYRVGTECTRPPSGGTDKLV-------------FVPSQPFLTALIQIFPALYQHIAGG--FSMEDLKKLGVILHGAVSVPISSDSSPFILP--SYTEAVLTSLQEAVLTALDVLQKAICVSSENLQVMYPAIFEQLLLFVEFSCKPPQYGKMETKHVANAKYNQIQLFAPAEWVALNYVPFAERSLEVVVDLYHKTACHKAVINEKVLQNI-IKTVRIPLGLKYACPAESTWKLAVSSLLKVLSIGLPVARQQASSGKFDTMWPELANAFEDFLFTKSTP-PDNLSIQEFQRNEAVDVEVVQLISSEILPFANFIPKEFVGRIMSMLNKGSIHSQSSSFTEAEMDMRMREDFSKVCFETLLQFSFSNKVSTPQ------------------EGFISRMALSVLLQRAQDVLRRYVEDERLSGRCPLPRQQVTEIIFVLKAISTLMDSLKKTQPENVDGNVWAQVIALYPTLVECITCTSPEVSSALKDALGPFKDFMQPPVSK----------VQNGES", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VLT1-1", "uniprot_id": "MON2_DROME", "id": "Q9VLT1-1", "name": "Protein MON2 homolog", "aln": "MSFVGGGGCGGQDVHKFVEALQADFKTLSLETKKKYPQIKEACEEAISKLCTAGSSQ---QNSVYYTVNQILYPLVQGCETKDLKIIKFCLGMMQRLITQQVVDQKGALYITNALWTLMENNIE-EVKVLQTVTLLLTTNTVVHGDTLAKALVLCFR--LHYA-KNPTIVNTAGATIRQLVSLVFERVYLEKDSVSSLQQQQSSGSPAEGEGGNQDVQTFASDAFLLFQDLVQLVNADQPYWLLGMTEMTRTFGLELLEAVLTNFSAVFHESNDFRLLLKERVCALVIKLFSPNVKHRQLPAPSNGNAPVPAEKPYFPISMRLLRLVAILIQKYHTILVTECEIFLSLIIKFLDPDK--PAWQRALALEVIHKLVTRSSLIAFFCKSYDLKNHATNIVHDMIAAMGSYIRYSLIN--------ASAMLNGQQNGVANSLTAMSGSNQCG--------FMFRGAYLPLVATYAPGVSKAVYLEMLDKIDASNIPDSYGISVGHAILLDMTRSIGGVIQRTP-----------------------ELHPSHNTAVITEEEHKPLCLQLVNSSWSALLSAFIPLVETS-IDEATTENILKAMQNYAALCGMLEQLQPRDAFIMAMCRASFPPHYAMSIFANTTQSDGDLRCHTRSGSQDLSSQFINSCSGDAGDFRPQIVAVGTPLPSASLPHSVMQAPVMLTNKNLQCMRAILFLAHNNGGILG-TSWHIVLQTLQHLVWILGLKPSTGGSLQAMPKPAVEANVGIQTAVMADLPVLSQMLSQLFESSQYLDDVALHHLIDALCKLSHEAMELAYAN-REPSLFAVAKLLETGLVN---------------------MPRIKVLWRPLTNHLLE-VCQHRHIR--MREWGVEAITYLVKSALQFK-----HKTPLKENMELQTMLLSPLSELST-----------------VLHADVRQRQLDCVLQILNTAGEILSFGWPAIIEIIG------------AVNEHHGEP------------LIRTAFQCLQLVITDFLTVMPWRCLPLCISTAAKFGSQTQELNISLTAIGLMWNISDFFNQ----------NQDKLMSTQLQDVSILPDFPG---TVKMPQFDKLWMCLYAKLGELCVDLRPAVRKSAGQTLFSTISAHGSLLNPPTWQALVWQVLFPLLDNVRALSSSASNEKVDASG-NILIHHSRNTAQKQWAETQVLTLSGVCRVFNTKRELLQMLGDFERAWSLILEFIQNAALSKNGEVSLAALKSLQEIMYHNTAER--------------------------TERALKDPQTAQE-------------------QDEEIWTIAWNIWLSIGMESTKMSTSTSAKLQQQNSNGAETQEDFYIPSQAFLTALIQIFPAIFQHIQVK--FTAADFDKFCTVLTNAVCIPVQTDAVPYIMS--TVSDTLLTPLHDGILDCMELIQKEATKPDSHISQLIPAIFRQLLIFSKFACAPPTFQQSVEHKYAKSSG-HYANNASVEVVSMNYIPFGEKSISICVKLYQTTATEDSVVQEQILHDI-VKALRTPLAMKYKCLSSSTWKLAISSLISVLHTGLKVAR--AKPQHFASLWDDLADTLDKFLFPASVCTIEDRGLEEIVLDETIDCQVIELLRDEVLPHSHEMPHQFIMQIVVLLNKGSIHSASDTNICYESDWKLREIFAKTCFETLLQFSLLEDHANTNNNRLNANVLTAGAAGAGGKDFAGRLAVTALLHRFQEVLKRFNDDERQSGKCPLPRFRLSEISFVLKAIATLVVSMKKAPASKVNKPAWDQLIGLYPYLVDCTTTTSPEVSRSLREALLQYTDLLQAPRSCSAATSNDNVIQSNGQE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P48563-1", "uniprot_id": "MON2_YEAST", "id": "P48563-1", "name": "Protein MON2", "aln": "------MAMNTGGFDSMQRQLEAELRSLSSESKRRNSTIRHASDKSIEILKRVHSFE------ELERHPDFALPFVLACQSRNAKMTTLAMQCLQGLSTVPSIPRSRLSEILDAFIEATHLAMEIQLKVLQVVPIFFKTYGKFIYGPLCKKLLLCCSNLLHVPNKAPVVVGTASATLQQLIDEIFDRLSIESVVDDKQYEVLISNSESIKVNVYRYDANKLFDNICSLNEISSNGAVSDEEMLLDIGDIPIDYGLEILESILKNSQKNLLECQDLQYLLRVKAIPLLLRCISSSRHFSTAVRSCR--------------CLKLL-----IRKEYLSILELELEVILSLLIHGISVESNLSGWQRVLSLELFKDLSQDPEIVNTLYMDYDNYPDKKHVFKYLLKECIVLLNS----------PEYITFLAPSKVVEKMDSP---------------------------LITTENSTVKTKFMHLLDKSNAPSINITYIISLILTICNHLCEGLNKSALESS----------------------PLEKKIEDKEREEGTGNDSTVVKVYSGLFSGLFELNKLFLYSTSLETSIFHLVVRAFQKLAHSAGVLSLKDKLRACMKLFSILITNNVTSSNQYSFNDTSKSAKNQHTRNIS---TSSVTTSPVESTKNPSRSIADSAQNKEMKR-----RLHPRNISSRQVSLLRALISLSISLGPIFDSESWRYTFLTWQWITYYIYGPSADFKESFYSEDIPPPPILTKSDVTSIESSLTKFFESTSSYSCSTFHLVLTRLILDSKNTLTLEQTNLNLNNDIGYHPLDAKDEIIPCIYNKAFFVNKIGELATYNCKKFLFGKNGKELWSLISTYMIKLISNREMDNDSLRLYTVRVFTDIIKKATNEVGNSDEQDNKVKQFGTLENLVIDSLMATINSIKQLDIGKQEIYNGTINVESDILFQLLLTLKEILNEFGELLMNSWTNIFNIINSPFEWTVEDTDFSVNEDIDDSSLFEGIVQKHKNMIQVSYDVFKLISDDFLQSLPMSVIKFVIDTLVNFVSQKRNLNISFSSISQFWLVGDYLRVRFNPETLNLSDEKRRSLSEKINNQKLIEIITSSSSHDWELYNGLWIYLLKNLINCTNDDRVEVKNGAVQTFFRIIDSHSVCFPP--WDLIFLEVIEPLLTKEWSTEELENET-----------------------DFINVTLQGLIKLYPEHFKDFKNNTTCAKEWSMLLDFLKRLLSSTSNNTKNAVILNYQTLLKEIITIED---------------------------------------------------------VPSDILKKCCEIFTDYNITYSDLSTNASSKTEY-----------------DCIYELITGFPPLYQLISKYDAMTDEFVEKVLLLFNSAIKYPLLPEFVQDKTKPSSMQKAILSGLDIFMTNDSKDTEILILLQLSTISILAFDTREKITKKLGPKLPKASLNRLPTFEAISYMSCSNLRNRIAKIDQFGISTLKAKHILRILKNLAEIIKRKSLITGSESDEIPIWVLASNCFCDLSNKIFKSLQEDAENPLKDNFCDLFINVIVVTLQRINPELDNLTEIDDLNEYSKYREILLENRIIDLFNERQLDTFIYAVWDCSFLYEFDELENALMQDCGTFSELSQKLSSFDFSCIFGSTTNPRFQTKYKCSLECLQDLVNFMLNTNEK--------------------LRKLTAPYLSARIALALRRYISDEYLIGRAPIPKLRKTELATLLNGLCVILRGVLDQNSTLGNKQIGVENLQTLSPLILRTIPVSHKMDGLQDKVLELSLGFTKLD-------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ...: . :::::::** * *:: . ::.*.:..* : : : :. *:: .* ::: *: :.: :* * : : . * : : . :* ::*:**.* :::.* . *.* ::** ** . * .**.**::*:: :*:*: *. : . * :::: . .. *:.: ::. :***:**::*.: : : ::: **: :. .*::: :*.. :. .. .::** : :.: ::* * *::***::: :. :. . * *.:::* .: : . :: : .** . .::.: :: :. . . . : . *: ::.:*** :...* * :*: .: ..: :: .. :..*: :: :: : : . :::* . * .* * * : .. : . . : . :: . . : . .. : .:. . . :: :::. :*::: *: * :. **: .: * * :.: : .: . .. : .: . : * *.. :. * : :::: .*: * :: . : . . : . : * . : ** :: :::: :.:: . :* : ...:* ::: . :. : : *: :::..* . ..*: : * : :**: *: * .*. :: ::. ::.:. .:. :*:.::: ::*: *** :* : : :.. .* :.::****:::*. :* :.*:: .:. .: : : :: **: * :* : * * *::.* **:* * :*. : *. :. :*: ** . .: : :** *: ::: : :: : *.::*:.:: *...:.. *.: . * :: . . : . : : . : . : : *: **.::* * :. ..*. :: .*: *: .: : .::*: *. : . : . :. : :: . : . . .: :. .: : : :. ..::: . ..* : .: . .: : . : .* : .. :: . :*:. : :. : : :: :. :* : : ..* . : : :: : : .. * . * * ** . . : ::: . * * .*:*: .** *:.*:*: : :*: :*:.:..:: .: . . : : : . *: * .: ..* .: : ", "identical_positions": 170, "similar_positions": 553, "identity": "9.08%" }, { "cls_id": "homologset.agr.RGD:1308809", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "O70552-1", "uniprot_id": "BTG4_MOUSE", "id": "O70552-1", "name": "Protein BTG4", "aln": "--------------------------------MRDEIATAVFFVTRLVKKHEKLSTQQIETFALKLMTILFEKYRGHWHPDCPSKGQAFRCIRINNNENKDPVLERACAESNVNFFHLGLPKEMTIWVDPYEVCCRYGEKKHPFTIASFKGRWENWELAQHVSCAVNRATGDCSSGTSSDEESCSREAQIIPKVNNPKSVYQVENFKQSLQPWFCLPRRKHLADGRGFLPGAACHPVPKSSKWCRPASRRVDRYHWVNAQLFSGQTAPGEPGEEALSSLKQK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4VFT8-1", "uniprot_id": "Q4VFT8_RAT", "id": "Q4VFT8-1", "name": "", "aln": "MGVVTVVRARLTAVRISLTHLEHCPYPDCFGIMRDEIATAVFFVTRLAKKHEKLSTQQIETFALKLMTVLFEKYRGHWHPDCPSKGQAFRCIRINNNENKDPVLERACSESNVNFFHLGLPKEMTIWVDPFEVCCRYGEKKHPFTIASFKGRWENWELAQSVSCAVNKATGDCSPSASSDEESCGREAQAIPKVNNPKSIYQVENFKPSFQPWLCLPRRKHLADGHGCLLGAAYHPMPKNSKWCRHAGHRVDRYHWVNTQLISGQTAPGELGEEALSSRKQK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NY30-1", "uniprot_id": "BTG4_HUMAN", "id": "Q9NY30-1", "name": "Protein BTG4", "aln": "--------------------------------MRDEIATTVFFVTRLVKKHDKLSKQQIEDFAEKLMTILFETYRSHWHSDCPSKGQAFRCIRINNNQNKDPILERACVESNVDFSHLGLPKEMTIWVDPFEVCCRYGEKNHPFTVASFKGRWEEWELYQQISYAVSRASSDVSSGTSCDEESCSKEPRVIPKVSNPKSIYQVENLKQPFQSWLQIPRKKNVVDGRVGLLGNTYHGSQKHPKCYRPAMHRLDRIL---------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *******:*******.***:***.**** ** ****:***.**.***.*****************:****:***** ****:* **************:*********:****:********:*** * :* **.:*:.* *..:*.*****.:*.: ****.****:*****:* .:*.*: :**:*::.**: * * : * * .* * * :*:** ", "identical_positions": 152, "similar_positions": 45, "identity": "53.9%" }, { "cls_id": "homologset.agr.RGD:1308810", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "O88700-1", "uniprot_id": "BLM_MOUSE", "id": "O88700-1", "name": "RecQ-like DNA helicase BLM", "aln": "-----------MAAVPLNNLQEQLQRHSARKLNNQPSLSKPKSLGFTFKKKT-SEGDVSVTSVSVVKTPALSDKDVNVSEA--FSFTESPLHKPKQQAKIEGFFKHFPGRQQSKG-TCSEPSLPATVQTAQDTLCTTPKTPTAKKLP--VAVFKKLEFSSSADSLS---DWADMDDFDMSAS-DAFASLAKNP-ATRVSTAQKMKKTKRNFFKPPPRKANAVKTDLTPPSPECLQVDLTKESEEEEEEEEEAEGADCLSRDVICIDNDSASEELTEKDTQESQSLKAHLGAERGDSEKKSHEDEAVFHSVQNTEYFEHNDNDYDIDFVPPSPEEIISTASSSLKCSSMLKDLDDSDKEKGILSTSEELLSKPEEMTTHKSDAGTSKDCDAQQIR-IQQQLIHVMEHICKLVDTVPTDELEALN--CGTELLQQRNIRRKLLAEAGFNGN----DVRLLGSLWR----HRPDSLDNTVQGDSCPVGHPNKELNSPYLLSHSPSTEE--------CLPT---TTPGKTGFSATPKNLFERPLLNSHLQKSFVS-SNWAETPRMEN----------RNESTDFPGSVLTSTTVKAQSKQAASGWNVERHGQASYD---------------------------IDNFNIDDFDDDDDDDDWENIMHNFPASKSSTATYPPIKEGGPVKSLSERISSAKAKFLPVVSTAQNTNLSESIQNCSDK-LAQNLSSKNPKHEHFQSLNFPHTKEMMKIFHKKFGLHNFRTNQLEAINAALLGEDCFILMPTGGGKSLCYQLPACVSPG----VTIVISPLRSLIVDQVQKLTSFDIPATYLTGDKTDSEAANIYLQLSKKDPIIKLLYVTPEKVCASNRLISTLENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPSVPVMALTATANPRVQKDILTQLKILRPQVFSMSFNRHNLKYYVLPKKPKKVAFDCLEWIRKHHPYDSGIIYCLSRRECDTMADTLQREGLAALAYHAGLSDSARDEVQHKWINQDNCQVICATIAFGMGIDKPDVRFVIHASLPKSMEGYYQESGRAGRDGEISHCVLFYTYHDVTRLKRLIMMEKDGNYHTKETHVNNLYSMVHYCENITECRRIQLLAYFGEKGFNPDFCKKYPDVSCDNCCKTK--DYKTKDVTDDVKNIIRFVQEHSSSPGTR---NIGPAGRFTLNMLVDIFLGSKSAKVKSG------IFGKGTTYSRHNAERLFKKLILDKILDEDLYINANDQPIAYVMLGTKAHSVLSGHLKVDFMETENSSSIKKQK--------ALVAK-VSQREEVVKKCLGELTEVCKLLGKVFGVHYFN-IFNTATLKKLAESLSSDPEVLLQIDGVTEDKLEKYGAEVIPVLQKYSEWTVPAEDGSPGA-----RGAPEDTEEE-EEEAP---------VSSHYFANQTRNERKRKKMSATHKPKRRRTSYGG-FRAKGGSTTCRKTTSKSKFYG--VTGSRSASCASQATS--SASRKLGIMAPPKP--VNRTFLRPSYAFS---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZQW1-1", "uniprot_id": "D3ZQW1_RAT", "id": "D3ZQW1-1", "name": "RecQ-like DNA helicase BLM", "aln": "--MFGSPVGWIMAAVPLNNLQEQLQRHSARKLKNQFSISKPKPSGFTFKKKT-PEG-----DVSVVRTPVLSDKDVNMSEA--LSYTEPPLHKPKQQSNIDGFFKNSPGGQQSKE-TCSELSLPEVVQIPQDASCTTPKTPAVKKPH--VAIFKKLEFSSSADSLS---DWADIDDFDVPAS-DAFVSLTRNP-TTRVSTAKKLSSSKRNFFKPPPR-ASAVKADLTPSSPECLQVDLTKEQEEE---------ADCLSRDVICIDTDPASEELLEKDVQEGLSLDARLGTERVDSAKKSHEDKAAFQSPQNALYFEHNDNDYDIDFVPPSPEEIISTASSSLKCSSMLKDLDDSDKEKDILSTSKDLS-KPEEMTTPKSDLGTNEDCDAQQTS-LQQQLIRVMEHICKLVDTVPIDELKALT--CGDKLLQQRDIRRKLLAEAGFNRN----DVNLLGSLWR----HRPDSLDNTVQCDSCPVGHPGKELNSPYLPSHSLSTEE--------CLPT---TASGKTGFSATPKSLSERPPLNSHLQKSFVS-SNWAETPRTES----------RTESTYFPGSVLTSTTVKDESKHVASGRDIEREVQASYD---------------------------IDNFNIDDFDDDDDDD-WENIMHNFSVSKSSTAAYPPIKEGGPVKSLSERISSAKAKFLPVASTAQNKNLSESIQNCSDK-FAQNLSSKNPKHEHFQSLNFPHTKEMMKIFRKKFGLHNFRTNQLEAINAALLGEDCFILMPTGGGKSLCYQLPACVSPG----VTIVISPLRSLIVDQVQKLTSFDIPATYLTGDKTDSEAANIYLQLSKKDPIIKLLYVTPEKVCASNRLISTLENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQRFPSVPVMALTATANPRVQKDILTQLKILRPQVFSMSFNRHNLKYYVLPKKPKKVALDCLEWIRKHHPYDSGIIYCLSRKECDTMADTLQREGLAALAYHAGLSDSARDEVQHKWINQDNCQVICATIAFGMGIDKPDVRFVVHASLPKSVEGYYQESGRAGRDGEISHCVLFYTYHDVTRLKRLIMMEKDGNYHTRETHVNNLYSMVHYCENITECRRIQLLAYFGEKGFNPDFCKKHPDVSCDNCCKTK--DYKTKDVTDDVKNIVRFVQEHSSSPGTR---NIGPAGRFTLNMLVDIFLGSKSAKVQSG------IFGKGSAYSRHNAERLFKKLILDKILDEDLYINANDQPIAYVMLGTKAHSVLSGHLKVDFMETENSSSVKKQK--------AAVAH-VSQRDEAVMKCLGELADVCKLLGKVFGVHYFN-IFNTATLKKLAESLSSDPEVLLQIDGVTEDKLEKYGAEIIPVLQKYAEWTLPAEGGSPGS-----RGSRRSTPEETEEEEA---------VSSHYFANQTRNERKRKKVSASQKPKRRRTSYGGGFRAKGGSTTCRKPSSKSKFSG--VTGSRSASCASQATS--AASRKLGIMAPPKP--VNRPFLRPAYAFS---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P54132-1", "uniprot_id": "BLM_HUMAN", "id": "P54132-1", "name": "RecQ-like DNA helicase BLM", "aln": "-----------MAAVPQNNLQEQLERHSARTLNNKLSLSKPKFSGFTFKKKTSSDNNVSVTNVSVAKTPVLRNKDVNVTED--FSFSEP-LPNTTNQQRVKDFFKNAPAGQETQR-GGSKSLLPDFLQTPKEVVCTTQNTPTVKKSR--DTALKKLEFSSSPDSLSTINDWDDMDDFDTSETSKSFVTPPQSH-FVRVSTAQKSKKGKRNFFKAQLYTTNTVKTDLPPPSSESEQIDLTEEQKDD---------SEWLSSDVICIDDGPIAEVHINEDAQESDSLKTHLEDERDNSEKKKNLEEAELHSTEKVPCIEFDDDDYDTDFVPPSPEEIISASSSSSKCLSTLKDLDTSDRKEDVLSTSKDLLSKPEKMSMQELNPETSTDCDARQIS-LQQQLIHVMEHICKLIDTIPDDKLKLLD--CGNELLQQRNIRRKLLTEVDFNKS----DASLLGSLWR----YRPDSLDGPMEGDSCPTGNSMKELNFSHLPSNSVSPGD--------CLLT---TTLGKTGFSATRKNLFERPLFNTHLQKSFVS-SNWAETPRLGK----------KNESSYFPGNVLTSTAVKDQNKHTASINDLERETQPSYD---------------------------IDNFDIDDFDDD---DDWEDIMHNLAASKSSTAAYQPIKEGRPIKSVSERLSSAKTDCLPVSSTAQNINFSESIQNYTDK-SAQNLASRNLKHERFQSLSFPHTKEMMKIFHKKFGLHNFRTNQLEAINAALLGEDCFILMPTGGGKSLCYQLPACVSPG----VTVVISPLRSLIVDQVQKLTSLDIPATYLTGDKTDSEATNIYLQLSKKDPIIKLLYVTPEKICASNRLISTLENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPSVPVMALTATANPRVQKDILTQLKILRPQVFSMSFNRHNLKYYVLPKKPKKVAFDCLEWIRKHHPYDSGIIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVICATIAFGMGIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKRLIMMEKDGNHHTRETHFNNLYSMVHYCENITECRRIQLLAYFGENGFNPDFCKKHPDVSCDNCCKTK--DYKTRDVTDDVKSIVRFVQEHSSSQGMRNIKHVGPSGRFTMNMLVDIFLGSKSAKIQSG------IFGKGSAYSRHNAERLFKKLILDKILDEDLYINANDQAIAYVMLGNKAQTVLNGNLKVDFMETENSSSVKKQK--------ALVAK-VSQREEMVKKCLGELTEVCKSLGKVFGVHYFN-IFNTVTLKKLAESLSSDPEVLLQIDGVTEDKLEKYGAEVISVLQKYSEWTSPAEDSSPGISLSSSRGPGRSAAEELDEEIP---------VSSHYFASKTRNERKRKKMPASQRSKRRKTASSG-SKAKGGSATCRKISSKTKSSS--IIGSSSASHTSQATS--GANSKLGIMAPPKP--INRPFLKPSYAFS---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6YUA3-1", "uniprot_id": "A0A8M6YUA3_DANRE", "id": "A0A8M6YUA3-1", "name": "RecQ-like DNA helicase BLM", "aln": "MTNERASCKYAMSSLPQNNLKEHLERHNN-AAQNKLSLLKPKPGGFCFKKKSSSGISKVEVPQKVTGSSVLANRSVNIPSN--FEVTKNPVTFSQKPERVAPKVNFFTAPSKPKTNTVNPLANPFALNKTPLVQSTIKALPKSAALPKDSTNDQTVELKHDISQLS-FNEWDDLDDFETPVKSRVASPVAGTS-TKKPSVSDQNTSSSCSSKCEETKVNEESQATETITAPKDVLSAANGVSTET---------AEREPEDSPIKKSKRPKKSVQHTALLSDTEDEEIIHCVSPDTNQKNFKSVAVAEKDKWGEPNVIDSDDCEENNHYEGFEDFIPPSPIPEEIS-----LSVSDKEK--SSSEPVTPANKKESSRSASGLPAPLDQSAKGLKGADDALFSVMESICCLVDTIPEHELIALT--CGTELLLQRAHRKRILAKGGSSRTSHSDSVSTPGFLNRPTFGVTPSNLTSLTPVTSGKREGVKTGFSFRKSIASVMSVGDESVFEDSDCIINGVETPGGTWNPNSSTKISAGRDTFNGSIQTLSKPESKTDKCYSRLS----------FNESSNQTDLFYSPKRVDSGSRNADSSVEINIAGSSSLRTGAEPVDD-----------------FLLDDFDIDDFDENDIPDYYEEPPSVLESRNNSGVKTPSVQEGGSSKSFER------KTFTPPAPKSIKTPNPEPLY-------------RNPAHDRFRGFNFPHSPEMMKIFHKKFGLHQFRFNQLEAINASLLGEDTFVLMPTGGGKSLCYQLPACVSAG----VTVVISPLRSLIVDQVQKLTTLDICATSLSGDKKDSEAARIYMQLSRKDPAIKLLYATPEKVCASGRMISALQNLYERGLLARLVIDEAHCVSQWGHDFRPDYKRLHELRRMFPNVPIMALTATATPRVQKDILNQLAMTRPQVFTMSFNRNNLKYSVLPKKPKKVDEECIQWIKKYYPRDSGIVYCLSRNDCDTLADSLQRAGIAALAYHAGLSDSDREYVQNKWINQDGCQVMCATIAFGMGIDKPDVRYVIHASLPKSVEGYYQESGRAGRDGEISHCVLFYSYSDVIRIKRLIAMDKDGNQQSKATHINNLHSMVHFCENVAECRRIQLLAYFGEHTFNTSFCKEHPEVICDNCARPN--KYKSRNVTDDVKKIARFVQDNCEKVGNRYG-KSAQQNRLTLNMLVEIFLGSKSARIQTG------MFGVGAAYSKHNAERLFKKLVLDNVLMEDLYITNSGQAVAYISAGPKAMSVLNGCMQVEFHETESASSIRKHR--------ASVCEKVSKREEMVKKCLGELNDLCKKLGKVFGIHYYN-IFSTATLKKIAETLSADPEVLLQIDGVTEDKLEKYGAEFIELLQKYSEWQLPAEAQAESSGWIDTTRGHQNDEDDNDDDDEG-----GGDVTSTYFRSNSGRGAKRKQGSYSRKPKRRKGSSGQNSSAKGGYSSNWSSSRGGGRGGGYRGGSRGAGRGSRSAPSGSAAKRPGFMSLPTPQAAARPFLKPSFSHL---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VGI8-1", "uniprot_id": "BLM_DROME", "id": "Q9VGI8-1", "name": "RecQ-like DNA helicase Blm", "aln": "------MSKKPVAQRKQLTLSSFIGLDGNSQSQPKSRAASVRSKPPAVYNPIFLDASSSDDETTEISSQSNNGTIATKKSS--RDPRTAKLKKHTYLDLSVSPLAKLSAKKYARDSPKKPTSLDLSVSPLAELLAKKSDRDSPKKPVQNENSYTYRGLSESPVENKSIGDTLRKPPQKERKTSIVWLSDSPEK-KVTQNERKILDSPLQRFSFEDFPNKENGNRHHLLTLPDSPPPPQPVKKPEK---------TMWQNETKTIQDKDSPANPLVSNNLASISTLLDSSRAPNTYKGSSRNLFEDSPEKSGSGE-QGYKLGSAKENEIPTKPATASLERNSVTSSPSPAAPLKPRYSVAFDNSLADYLKDLAQNDNFSIDPNKQNTETLKSTLGFFRNTYVELMEKYCSLIDQIPAMHFNEIAGFQPNTFLKLKVMRQKFKARTQLVQNSLDKKESQLKAEQEALEKEEIEMQAEQAQQTVLSSSSPEKSRPIMPLPKVQEIKDEK--IPNRNQLIHDLCGEPDNFSPPSSPRDTQLIPKRQQLINDLCGEPDDFSPPSKQNDPHLLRKCEELVHDLCEEPDDYLAQSMMLDGDLEEEQLNGPTQGTTTSGMDDDEDDLEGLLAEIEDEHQKMQGRRSEFNGYSYKELEAVKVKEKHKETPINISLDDDGFPEYDEAMFEQMHSQAAANKSRVSSAGPSTSKSVVPTKQTSALHSQKLSGNFHANVHNDGITGEFDGQKFEHSTRLMHGLSYSFGLKSFRPNQLQVINATLLGNDCFVLMPTGGGKSLCYQLPAILTEG----VTIVISPLKSLIFDQINKLASLDICAKSLSGEQKMADVMAIYRDLESQPPMVKLLYVTPEKISSSARFQDTLDTLNSNNYISRFVIDEAHCVSQWGHDFRPDYKKLGVLKKRFPNVPTIALTATATPRVRLDILAQLNLKNCKWFLSSFNRSNLRYRVLPKKGVSTLDDISRYIRSKPQHFSGIIYCLSRKECDETSKKMCKDGVRAVSYHAGLTDTDRESRQKDWLTG-KMRVICATVAFGMGIDKPDVRFVLHYSLPKSIEGYYQEAGRAGRDGDVADCILYYNYSDMLRIKKMLDSDKALQYNVKKIHVDNLYRIVGYCENLTDCRRAQQLDYFGEH-FTSEQCLENRETACDNCINKR--AYKAVDALEHARKAARAVKDLCSG-----------RSRFTLLHIADVLKGSKIKKIIDFNHHKTPHHGVLKDWDKNDVHRLLRKMVIDGFLREDLIFTN-DFPQAYLYLGNNISKLMEGTPNFEFAVTKNAKEAKAAVGSVSDGATSSTADGQSGMREIHERCYTDLLDLCRTIASQRNVTMAS-IMNIQALKSMAETLPITEKDMCSIPHVTKANFDKYGAKLLEITSNYASEKLLMQAVLDEEEEQAAAKQRPSTSGWNNESVDW-----DMAVASQGNANTSG-ASGFNSFRAGKRKKIYKSGASKRYKTSTTSPAARKTTSARGRGG--RAGAKRAESSASSAS--------GWKSKKTGNSFGFDLMPLPGSK----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P35187-1", "uniprot_id": "SGS1_YEAST", "id": "P35187-1", "name": "ATP-dependent helicase SGS1", "aln": "-----------MVTKPSHNLRREHKWLKETATLQEDKDFVFQAIQKHIANKRPKTNSPPTTPSKDECGPGTTNFITSIPASGPTNTATKQHEVMQTLSNDTEWLSYTATSNQYADVPMVDIPASTSVVSNPRTPNGSKTHNFNTFRPHMASSLVENDSSRNLGSRNNNKSVIDNSSIGKQLENDIKLEVIRLQGSLIMALKEQSKLLLQKCSIIESTSLSEDAKRLQLSRDIRPQLSNMSIRIDS--------LEKEIIKAKKDGMSKDQSKGRSQVSSQDDNIISSILPSPLEYNTSSRNSNLTSTTATTVTKALAITGAKQNITNNTGKNSNNDSNNDDLIQVLDDEDDIDCDPPVILKEGAP-HSPAFPHLHMTSEEQDELTRRRNMRSREPVNYRIPDRDDPFDYVMGKSLRDDYPDVE--REEDELTMEAEDDAHSSYMTTRDEEKEENELLNQSDFDFVVNDDLDPTQDTDYHDNMDVSANIQESSQEGDTRSTITLSQN-------KNVQVILSSPTAQSVPSNGQNQIGVEHIDLLEDDLEKDAILDDSMSFSFG-------------RQHMPMSHSDLELIDSEKENEDFEEDNNNNGIEYLS-----------------------------DSDLERFDEER--ENRTQVADIQELDNDLKIITERKLTGDNEHPPPSWSPKIKREKSSVSQKDEEDDFDDDFS-------LSDIVSKSNLSSKTNGPTYPWSDEVLYRLHEVFKLPGFRPNQLEAVNATLQGKDVFVLMPTGGGKSLCYQLPAVVKSGKTHGTTIVISPLISLMQDQVEHLLNKNIKASMFSSRGTAEQRRQTFNLFING--LLDLVYISPEMISASEQCKRAISRLYADGKLARIVVDEAHCVSNWGHDFRPDYKELKFFKREYPDIPMIALTATASEQVRMDIIHNLELKEPVFLKQSFNRTNLYYEVN-KKTKNTIFEICDAVKSRFKNQTGIIYCHSKKSCEQTSAQMQRNGIKCAYYHAGMEPDERLSVQKAWQAD-EIQVICATVAFGMGIDKPDVRFVYHFTVPRTLEGYYQETGRAGRDGNYSYCITYFSFRDIRTMQTMIQKDKNLDRENKEKHLNKLQQVMAYCDNVTDCRRKLVLSYFNED-FDSKLCHKN----CDNCRNSANVINEERDVTEPAKKIVKLVESIQNE-------------RVTIIYCQDVFKGSRSSKIVQANHDTLEEHGIGKSMQKSEIERIFFHLITIRVLQEYSIMNNSGFASSYVKVGPNAKKLLTGKMEIKMQFTISAPNSRPSTSSSFQANEDNIPVIAQKSTTIGGNVAANPPRFISAKEHLRSYTYGGSTMGSSHPITLKNTSDLRSTQELNNLRMTYERLRELSLNLGNRMVPPVGNFMPDSILKKMAAILPMNDSAFATLGTVEDKYRRRFKYFKATIADLSKKRSSEDHEKYDTILNDEFVNRAAASSNGIAQSTGTKSKFFGANLNEAKENEQIINQIRQSQLPKNTTSSKSGTRSISKSSKKSANGRRGFRNYRGHYRGRK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .* : : . : . . .. . . . . : . . . . . . . . : : . . .. . . . :. . . : ::. . : * . : . . : . :. : : : . : . . . . . :: : : .. . . . : .. . . .: : .:: : * * ** ***:.:**:* *:* *:**************** :. * .*:***** **: **:::* . :* *. ::. . : : : :.*:* :** :.:* : ::. * ::*:*:*******:****** ***.: ::: :*.:* :******. :*: **: :* : . : **** ** * * ** .. : ::. :**:** *:..*: : : : *: . ****: * *: * :*:***:************:* * ::*:::******:*******: : *: ::.: *: :: :: :* : . : *.::* :: :*:*:::*** * **.*. * .. * : **** . : :. : .:. : *:. . *.*: ::: **: :: .* .: : .*:: ::: .* * :. . . :*: * : .:: * :..: * .: . : . . : . . . :. .: :: . :* .: : . :. . ::. ::. : . . : . . :. . . . . . :. : . : ", "identical_positions": 171, "similar_positions": 292, "identity": "11.04%" }, { "cls_id": "homologset.agr.RGD:1308811", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AAR8-1", "uniprot_id": "A0A8I6AAR8_RAT", "id": "A0A8I6AAR8-1", "name": "Mitochondrial S-adenosylmethionine carrier protein", "aln": "---------------------MDAPGFTASLVAGGVAGAAVDLILFPLDTIKTRLQSPQGFNQAGGFRGIYAGVPSAAIGSFPNAAAFFLTYEYVKS--------LLHTDSTSHFRPMKHMLAASTGEVVACLIRVPSEVVKQRAQVSASSKT---LQIFSTILSEEGIQ-GLYRGYKSTVLREIPFSLVQFPLWESLKALWSWRRGR-VVESWQSAVCGAFAGGFAAAVTTPLDVAKTRIMLAKAGSSTAVGNVLSAMHGVWRSQGLAGLFAGVFPRMAAISMGGFIFLGAYDQTRSLLLEVGRKSP----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5U680-1", "uniprot_id": "SAMC_MOUSE", "id": "Q5U680-1", "name": "Mitochondrial S-adenosylmethionine carrier protein", "aln": "---------------------MDAPGFTASLVAGGVAGVSVDLILFPLDTIKTRLQSPQGFNKAGGFRGIYAGVPSAAVGSFPNAAAFFLTYEYVKS--------LLHTDSTSHFKPVKHMLAASTGEVVACLIRVPSEVVKQRAQVSASSKT---LQIFLTILSEEGIQ-GLYRGYKSTVLREIPFSLVQFPLWESLKALWAWRRGH-VVDSWQSAVCGAFAGGFAAAVTTPLDVAKTRIMLAKAGSSTAVGNVLSAMHGVWRSQGLAGLFAGVLPRMAAISMGGFIFLGAYDQARSLLLEVGRKSP----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q70HW3-1", "uniprot_id": "SAMC_HUMAN", "id": "Q70HW3-1", "name": "Mitochondrial S-adenosylmethionine carrier protein", "aln": "---------------------MDRPGFVAALVAGGVAGVSVDLILFPLDTIKTRLQSPQGFSKAGGFHGIYAGVPSAAIGSFPNAAAFFITYEYVKW--------FLHADSSSYLTPMKHMLAASAGEVVACLIRVPSEVVKQRAQVSASTRT---FQIFSNILYEEGIQ-GLYRGYKSTVLREIPFSLVQFPLWESLKALWSWRQDH-VVDSWQSAVCGAFAGGFAAAVTTPLDVAKTRITLAKAGSSTADGNVLSVLHGVWRSQGLAGLFAGVFPRMAAISLGGFIFLGAYDRTHSLLLEVGRKSP----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q4V9P0-1", "uniprot_id": "SAMC_DANRE", "id": "Q4V9P0-1", "name": "Mitochondrial S-adenosylmethionine carrier protein", "aln": "---------------------MDRREFTASLVAGGCAGMCVDLTLFPLDTIKTRLQSQQGFYKAGGFRGIYAGVPSAAIGSFPNAAAFFVTYESTKS--------VFSGYTTTNLAPITHMLAASLGEIVACLIRVPTEVVKQRTQANPSIST---YRVLLNSLQEEGFR-GLYRGYGSTVLREIPFSLVQFPLWEYLKAVWWRRQGG-RLDSWQAAVCGALAGGVAAFVTTPLDVAKTWIMLAKAGTSTASGNIPMVLCEVWRSRGIPGLFAGSIPRVMFISMGGFIFLGAYEKVRRTLL-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VBN7-2", "uniprot_id": "SAMC_DROME", "id": "Q9VBN7-2", "name": "S-adenosylmethionine mitochondrial carrier protein homolog", "aln": "MAAELGLESAAGSVAIKMQEPVNKLKFFHALVAGGVAGMVVDIALFPIDTVKTRLQSELGFWRAGGFRGIYKGLAPAAAGSAPTAALFFCTYECGKQ--------FLSSVTQTKDSPYVHMAAASAAEVLACLIRVPVEIAKQRSQTLQGNKQSG-LQILLRAYRTEGLKRGLYRGFGSTIMREIPFSLIQFPLWEYFKLQWTPLTGF-DSTPFSVALCGAVAGGISAGLTTPLDVVKTRIMLAERESLNRRRSARRILHGIYLERGFSGLFAGFVPRVLWITLGGAFFFGFYDLTTRILGATSTDH-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38921-1", "uniprot_id": "PET8_YEAST", "id": "P38921-1", "name": "Mitochondrial S-adenosylmethionine carrier protein", "aln": "---------------------MN--TFFLSLLSGAAAGTSTDLVFFPIDTIKTRLQAKGGFFANGGYKGIYRGLGSAVVASAPGASLFFISYDYMKVKSRPYISKLYSQGSEQLIDTTTHMLSSSIGEICACLVRVPAEVVKQRTQVHSTNSSWQTLQSILRNDNKEGLRKNLYRGWSTTIMREIPFTCIQFPLYEYLKKTWAKANGQSQVEPWKGAICGSIAGGIAAATTTPLDFLKTRLMLNKTTASLG-----SVIIRIYREEGPAVFFSGVGPRTMWISAGGAIFLGMYETVHSLLSKSFPTAGEMRA", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: * :*::*. ** .*: :**:**:*****: ** **::*** *: .*. .* * *: ** :*: * . : . ** ::* .*: ***:*** *:.***:*. : : **:: .****: :*::*****: :****:* :* * . .:. *:**:.***.:* *****. ** : * : : : :: ..* . :*:* ** *: ** :*:* *: . * ", "identical_positions": 92, "similar_positions": 72, "identity": "29.49%" }, { "cls_id": "homologset.agr.RGD:1308812", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZRZ8-1", "uniprot_id": "A0A8I5ZRZ8_RAT", "id": "A0A8I5ZRZ8-1", "name": "", "aln": "MAGKDSGNLKTVRLWRDAALRARKLRSNLRQLTLS----CPGAGGDSLESPDAPQLVLPANIGDIEVLNLGNNGLEDVPEGLGSALGSLRVLVLRRNRFARLPPAVAELGHHLTELDVSHNRLTILGAEVVSALRELRKLNLSHNQLPALPAQLGALAHLEELDVSFNRLAHLPDSFSCLNHLRTLDVDHNQLTAFPQQLLQLAALEELDVSSNRLRGLPEDISALRALKILWLSGAELGTLPSGFCELASLESLMLDNNGLQALPDEFSRLQRLKMLNLSSNLFEEFPAALLPLAGLEELYLSRNQLTSVPSLIAGLGRLLTLWLDNNRIRYLPDSIVELTGLEELVLQGNQIAVLPDNFGQLSRVGLWKIKDNPLIQPPYEVCMKGIPYIAAYQKELAHSQPAVQPRLKLLLMGHKAAGKTLLRHCLTEDKVEGGQGGGDKEKSYLPFPPLGSKGIEVTSWTADASRGLRFIVYDLAGDESYEVIQPFFLSPGALYVLVVNLATYEPRCFPTTVGSFLHRVGARVPHAVVCIVGTHADLCGERELEEKCLDIHRQIALQEKHDAEGLSHLAKVVDEALARDFELRSASPHAAYYGVSDKNLRRRKAHFQYLLNHRLQILSPVLPVSCRDPL-QLQRLRDKLLSVAEHREIFPNLHRVLPRSWQVLEELHFQPPQAQRLWLSWWDSARLGLQAGLTEDRLQSALSYLHESGKLLYFEDSPALKEHVFHNLTRLIDILNVFFQRDASLLLHKLLLGTNGEGEGEGESFPTIAVPTPGQDPLRATQLHHYVEGFLLHGLLPAHIIRLLLKPHVQAQQDLQLLLELLEKMGLCYCLNKPKGKPLNGSAAWYKFPCYVQNEVPHAEAWING-TNLAGQSFVAEQLQIEYSFPFTFPPGLFARYSVQINSHVVHRSDGKFQIFAYRGKVPVVVSYRPAKGVLQPDTLSIASHASLPNIWTAWQAITPLVEELNVLLQEWPGLHYTVHILCSKCLKRGSPNPHAFPGELLSQPRPEGVAEIICPKNGSERVNVALVYPPTPTVISPCSKKNVGEKHRNQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3V1N1-1", "uniprot_id": "MFHA1_MOUSE", "id": "Q3V1N1-1", "name": "Malignant fibrous histiocytoma-amplified sequence 1 homolog", "aln": "MAGQDSGNLKTVRLWRDAALRARKLRSNLRQLTLS----CPGAGGDPLESPDAPQLVLPANIGDIEVLNLGNNGLEDVPEGLGSALGSLRVLVLRRNRFARLPPAVAELGHHLTELDVSHNRLTILGAEVVSALRELRKLNLSHNQLPALPAQLGALAHLEELDVSFNRLAHLPDSFSCLNHLRTLDVDHNQLTAFPQQLLQLAALEELDVSSNRLRGLPEDISALRALKILWLSGAELGTLPRGFCELASLESLMLDNNGLQALPDEFSRLQRLKMLNLSSNLFEEFPAALLPLAGLEELYLSRNQLTSVPSLIAGLGRLLTLWLDNNRIRYLPDSIVELTGLEELVLQGNQIAVLPDNFGQLSRVGLWKIKDNPLIQPPYEVCMKGIPYIAAYQKELAHSQPAVQPRLKLLLMGHKAAGKTLLRHCLTEDKVEGGQGGGDKEKSYLPFPPLGSKGIEVTSWTADASRGLRFIVYDLAGDESYEVIQPFFLSPGALYVLVVNLATYEPRCFPTTVGSFLHRVGARVPHAVVCIVGTHADLCGERELEEKCLDIHRQIALQEKNDAEGLSHLAKVVDEALARDFELRSASPHAAYYGVSDKNLRRRKAHFQYLLNHRLQILSPVLPVSCRDPL-QLQRLRDKLLSVAEHREIFPNLHRVLPRSWQVLEELHFQPPQAQRLWLSWWDSARLGLQAGLTEDRLQSALSYLHESGKLLYFEDSPALKEHVFHNLTRLIDILNVFFQRDASLLLHKLLLGTNGEGEGEGESFPTIAVPSPGQDPLRATQLHHYVEGFLLHGLLPAHIIRLLLKPHVQAQQDLQLLLELLEKMGLCYCLNKPKGKPLNGSAAWYKFPCYVQNEVPHAEAWING-TNLAGQSFVAEQLQIEYSFPFTFPPGLFARYSVQINSHVVHRSDGKFQIFAYRGKVPVVVSYRPAKGVLQPDTLSIASHASLPNIWTAWQAITPLVEELNVLLQEWPGLHYTVHILCSKCLKRGSPNPHAFPGELLSQPRPEGVAEIICPKNGSERVNVALVYPPTPTVISPCSKKNVGEKHRNQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y4C4-1", "uniprot_id": "MFHA1_HUMAN", "id": "Q9Y4C4-1", "name": "Malignant fibrous histiocytoma-amplified sequence 1", "aln": "MAGMDSGNLKTARLWRDAALRARKLRSNLRQLTLTAAGACPGAGADALESPASPQLVLPANLGDIEALNLGNNGLEEVPEGLGSALGSLRVLVLRRNRFARLPPAVAELGHHLTELDVSHNRLTALGAEVVSALRELRKLNLSHNQLPALPAQLGALAHLEELDVSFNRLAHLPDSLSCLSRLRTLDVDHNQLTAFPRQLLQLVALEELDVSSNRLRGLPEDISALRALKILWLSGAELGTLPAGFCELASLESLMLDNNGLQALPAQFSCLQRLKMLNLSSNLFEEFPAALLPLAGLEELYLSRNQLTSVPSLISGLGRLLTLWLDNNRIRYLPDSIVELTGLEELVLQGNQIAVLPDHFGQLSRVGLWKIKDNPLIQPPYEVCMKGIPYIAAYQKELAHSQPAVQPRLKLLLMGHKAAGKTLLRHCLTEERVEGCPGGGDKEKCYPPSPPPVSKGIEVTSWTADASRGLRFIVYDLAGDESYEVIQPFFLSPGALYVLVVNLATYEPRHFPTTVGSFLHRVGARVPHAVVCIVGTHADLCGERELEEKCLDIHRQIALQEKHDAEGLSRLAKVVDEALARDFELRSASPHAAYYGVSDKNLRRRKAHFQYLLNHRLQILSPVLPVSCRDPR-HLRRLRDKLLSVAEHREIFPNLHRVLPRSWQVLEELHFQPPQAQRLWLSWWDSARLGLQAGLTEDRLQSALSYLHESGKLLYFEDSPALKEHVFHNLTRLIDILNVFFQRDPSLLLHKLLLGTSGEGKAEGESSPPMARSTPSQELLRATQLHQYVEGFLLHGLLPAHVIRLLLKPHVQAQQDLQLLLELLEKMGLCYCLNKPKGKPLNGSTAWYKFPCYVQNEVPHAEAWING-TNLAGQSFVAEQLQIEYSFPFTFPLGLFARYSVQINSHVVHRSDGKFQIFAYRGKVPVVVSYRPARGVLQPDTLSIASHASLPNIWTAWQAITPLVEELNVLLQEWPGLHYTVHILCSKCLKRGSPNPHAFPGELLSQPRPEGVAEIICPKNGSERVNVALVYPPTPTVISPCSKKNVGEKHRNQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B6D2-1", "uniprot_id": "A0ACD6B6D2_DANRE", "id": "A0ACD6B6D2-1", "name": "", "aln": "MAEET--NLKTARLWRDAALRSRKLRSNLRQLTLS--------------TKNSQKITLPEDIKEIEVLNLGNNSLQELPEGLGSTLTKLRILILRRNKFATVPSAVFQLS-QLVELDISHNCLNHF-SEDIDLLKGLKKLCFSHNKIQYLPSQIGTLQSLEELDISFNELHDFPRSFSQLRKLRTLDVDHNKLQRFPSEILALSDLEELDCSGNKLEGLPGNIMMLQSIKILWLSSTHLLSLPETFCELQNLESLMLDNNFLTRLPQSFGKLQKLKMLNLSSNSFEDFPQVIIKLTKLEELYLSRNKLTFLPEEVGQLCNLANLWLDNNSITFLPDSIVELGKLEELVLQGNQIAILPDNFGKLAKVNIWKVKDNPLIQPPYEVCMKGIPYIAAYQKELAHSQPAIKPRLKLVLMGQGNAGKTTLRQCIVSKQSD-------------TKMAIGCRGIDVTNWVADAERSLTFIVYDLSGKQNYDLIKPFFLSPGALYVLVVNLKLYTSKSFYSHVGSFLHLLSAKVPHAVVCIVGTHSDLCEEVEVEEKCLDIHRQISFQEKMDIDCLHVLALQVDEALEQGYDVRTSTPHVLFYGVTDKNLRRKKSQLQYMLNNRLQILSPVICVSCVAAQRNIQHLKEKLMSVADHREIFPNLHRVLPKSWQMLEELHFKP---QDLWLSWWDSARLGLQAGLTEDRLQSALSYLHESGKLLYFEDSTTLKEYVFHNLPRFIAILNVFFQRDLPAMLEKLQA----EGD-DGDN----AVS---------TQMHSHVEGFLSHGLLPSNVIRLLLKPLVQTQQDLHLIMELLEKMGVCYCVNKPRCKPLNGATVWYKFPSQDINEEPKPEASGSGGLSIPGQFFSVEQLQIEYRFPFFTPLGLFARFSVQINSHVVQRSDGKHHIFAYRGKVPVTVSYRSSRSRFQPEILSISSHASLPNIWTAWQAIIPLVEELNVLLQEWPGLHYSVHVLCSKCLKRGSPYPHSFPGELLSQPRPEGLTEIICPKNGSERVNVALVYPPTPTVISPSHK----------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** ****.*********:************: : : ::.** :: :**.******.*:::******:* .**:*:****:** :*.** :*. :*.***:*** *. : :* :. *: *:** :***:: **:*:*:* *****:***.* .:* *:* * :*********:* ** ::* * ***** *.*:*.*** :* *:::******.:.* :** **** .********* * ** .*. **:********* **:** .:: *: *********:** :*. :. * .* .****** * :******** ************:***:**:*::*.:**:*********************************::*****:***: **** **:*:...: : . . .:**:**.*.***.*.* ******:*.:.*::*:**************** * .: * : ****** :.*:************:*** * *:***********::*** * : * ** ***** :.:::*:::**. :***:******:*:::**:**:********: *** . ::::*::**:***:*************:***:******:* * *****************************************.:***:*****.*:* ********* . :*.** **. :*:. * . **:* :***** *****:::******* **:****:*::*******:***:***: *****::.*****. ** *:.** .* .:.** * .******* *** * *****:*********:*****.:**********.****.::. :**: ***:*************** ******************:**:*********** **:*************::***************************. * ", "identical_positions": 665, "similar_positions": 208, "identity": "63.09%" }, { "cls_id": "homologset.agr.RGD:1308813", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U2X6-1", "uniprot_id": "CCD47_RAT", "id": "Q5U2X6-1", "name": "PAT complex subunit CCDC47", "aln": "-MKAFCAFCVVLLVFGSVSEAK---FDDFE--DEEDIVEYDD-NDFAEFEDVVEDSVT----ESPQR----VINTEDDEDEATVELE-GQDEGQEGDFEDADTQEGDTESEPYDDEEFEGYED---KPDTSSNKNKDPITIVDVPAHLQNSWESYYLEILMVTGLLAYIMNYIIGKNKNSRLAQAWFNSHRELLESNFTLVGDDGTNKEATSTGKLNQENEHIYNLWCSGRVCCEGMLIQLRFLKRQDLLNVLARMMRPVSDQVQIKVTMNDEDMDTYVFAVGTRKALLRLQKEMQDLSEFCSDKPKSGAKYGLPDSLAILSEMGEVTEGMMDT-KMVHFLTHYADKIESVHFSDQFSGPKIMQEEGQPLKLPDTKRTLLFTFNVPGSGNTYPKDMEALLPLMNMVIYSIDKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQRRLEEAALRREQKKLEKKQMKMKQIKVKAM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D024-1", "uniprot_id": "CCD47_MOUSE", "id": "Q9D024-1", "name": "PAT complex subunit CCDC47", "aln": "-MKAFYAFCVVLLVFGSVSEAK---FDDFE--DEEDIVEYDD-NDFAEFEDVMEDSVT----ESPQR----VISTEDDEDEATVELE-GQDESQEGDFEDADTQEGDTESEPYDDEEFEGYED---KPDTSSNKNKDPITIVDVPAHLQNSWESYYLEILMVTGLLAYIMNYIIGKNKNSRLAQAWFNSHRELLESNFTLVGDDGTNKEATSTGKLNQENEHIYNLWCSGRVCCEGMLIQLRFLKRQDLLNVLARMMRPVSDQVQIKVTMNDEDMDTYVFAVGTRKALLRLQKEMQDLSEFCSDKPKSGAKYGLPDSLAILSEMGEVTEGMMDT-KMVHFLTHYADKIESVHFSDQFSGPKIMQEEGQPLKLPDTKRTLLFTFNVPGSGNTYPKDMESLLPLMNMVIYSIDKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQRRLEEAALRREQKKLEKKQMKMKQIKVKAM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96A33-1", "uniprot_id": "CCD47_HUMAN", "id": "Q96A33-1", "name": "PAT complex subunit CCDC47", "aln": "-MKAFHTFCVVLLVFGSVSEAK---FDDFE--DEEDIVEYDD-NDFAEFEDVMEDSVT----ESPQR----VIITEDDEDETTVELE-GQDENQEGDFEDADTQEGDTESEPYDDEEFEGYED---KPDTSSSKNKDPITIVDVPAHLQNSWESYYLEILMVTGLLAYIMNYIIGKNKNSRLAQAWFNTHRELLESNFTLVGDDGTNKEATSTGKLNQENEHIYNLWCSGRVCCEGMLIQLRFLKRQDLLNVLARMMRPVSDQVQIKVTMNDEDMDTYVFAVGTRKALVRLQKEMQDLSEFCSDKPKSGAKYGLPDSLAILSEMGEVTDGMMDT-KMVHFLTHYADKIESVHFSDQFSGPKIMQEEGQPLKLPDTKRTLLFTFNVPGSGNTYPKDMEALLPLMNMVIYSIDKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQRRLEEAALRREQKKLEKKQMKMKQIKVKAM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q66I12-1", "uniprot_id": "CCD47_DANRE", "id": "Q66I12-1", "name": "PAT complex subunit CCDC47", "aln": "MRHLVFLLLPALLLLLALPDTRGRYNDDFD--DGEDIAEFDD-NDFAEFEDVSEDPAVDVEKEPPPRPAPSSTPVEDDEDEATVENEDGQDE-----FEDTDAQDQDMYN-KYDTDEFEGYE-------KSNPSFKDTLIYREVPAHLQNSWESYYMEILMVTGLLAYIMNYIIGKNKNSRLAQAWFNSHRELLESNFALVGDDGTSKEATSTGKLNQENEHIYNLWCSGRVCCEGMLIQLKFLKRQDLLNVLARMMRPTCDQVQVRVTLNDEDMDTFVFAVGSRKAMARMQKEMQDLSEFCGDKPKSGAKYGIPDSLTILSEMGEVTDGVMDN-KMVHYLTSHADKIESIHFSDQFSGPKVMQEEGQPLKLPETKKTLLFTFNVPGMGNTSPKDMDSLLPLMNMVIYSIDKVKKLRLNREGKQKADRNRARVEENFLKQTHAQRQEAAQTRREEKKRAEKERIMNEEDPERQRRLEEAAQRREQKKMEKKQMKMKQIKVKAM", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VQR9-1", "uniprot_id": "Q9VQR9_DROME", "id": "Q9VQR9-1", "name": "PAT complex subunit CCDC47", "aln": "-MRPVFAFLLLALICFASTKSE----SDFEEDDSDDFAEFDDGNFYAEPAAKNADSFS-----GGAG----SSHGESRDDPPAKEPR-KQAQNQESDEEDGLVEDDDEFEHFQDEEEFEGYDGGDSKDPPIDQKVEPKLNIPNIPLHFRTHWDSYWMEMLMVAGLLAYFANFFAGKAKNARLAQLWFSTHRALLDENFALVGDDGKAENENPG--LIKESESLYTLWCSGRTCCEGMLVELKMIKRQDLVSLVAGLMRPQLDQAHIKIELTRGVMDAFVFAVGTKKTITKLFKEYTDLSKFCSLVGKPEDRYNVPTGFGVLSEIPEATSAILES-RIITALNKYQSYIDYLHISDQFSGP-IQQEEGGTLKQPETKAVLLAGFNLP-----KHAEMETIKPLLLLIFYLMERLKTYRMSKEGKAKSDKNRQRVEEEFLKSTHAARAEAAAQRREDKRKQEKERILADEDPEKQRRWEAKEQKRQAKRNAP---KMKRLAVKSL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53723-1", "uniprot_id": "YN8B_YEAST", "id": "P53723-1", "name": "UPF0674 endoplasmic reticulum membrane protein YNR021W", "aln": "MSSSIFGPLTGFLERVNSLNAP---YQALSYDEQKAMTIWQRVKFYNWTFELCALGVL--------------------------------------FLVYAFYKFGNSVNLKRGNQIFQSLHS----------FLANDLKFSRVGFNIND------SKIFTVEHQNTWFSSFATGR---SAIKSINLNLHLVARSNPFSMC------------------LEYLLGFFFASLKSKQ-LEEFMEIVIRPNGILVTSESAHPNKNAHEILTKFR------FVTSIVNKEFMNQARTEN-----YFLSIAHTSENDKLPNNFVYMSDVNQLSGFMFHYSKPYEVLSQAGNLLKYISFTDLPVNPPRDDKEWESSIEPKAIIRCAVPQNENELKLLNQIISLVVEIYDGFTQDLVQQSPNLFITNDILKRTTNLRQQELNKIKKFMKETELELAKEKKLELEKAKRRQLKASGQQEKVDQKMKEKRERRLKNKQRTRFQ---------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * .: . :. : . :. :: : : : : . . : *:. . : : ::. ::: * ::: .: *: : : . :. * .. *:: * : :: :. . : : :.:: * : : : : :* : .: : :* :: .:: : : .* : :. . :* .: :*:: : : ::. : *. . :. : ::* .* ::* . *.: * : : ::: . :..: :: . * : ::: * : . * * :: : .: ::.:: . : *: : .*. *. : ", "identical_positions": 26, "similar_positions": 141, "identity": "5.17%" }, { "cls_id": "homologset.agr.RGD:1308815", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q3T1L5-1", "uniprot_id": "ALG6_RAT", "id": "Q3T1L5-1", "name": "Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase", "aln": "-------------MESWTWMTV-------------------VVLLGLTVRWTVSLNSYSGAGKPPMFGDYEAQRHWQEITLNLPVKQWYFNSSDNNLQYWGLDYPPLTAYHSLLCAYVAKFINPDWVALHTSRGYES--QAHKLFMRTTVLAADLLIYIPAVLLYCYSLKEIS---PKRKIASALCILLYPGLILIDYGHFQYNSVSLGFALWGVLGVSCDWDLLGSLAFCLALNYKQMELYHSLPFFCFLLGKCFKKGLRGKGSALFIRIACTVVASFLLCWLP--FLTE-REHALQVVRRLFPVDRGLFEDKVANIWCSLNVFLKIKDILPRHIQIAISFCFTFLSLLPACIKLTVQPSAKGFRFTLVSCALSFFLFSFQVHEKSILLVSLPVCLVLT----EIPFMSTWFLLVSTFSMLPLLLKDQLLLPSVVTVMAFLIACSTFFPMFENTSEEQLQLKSFAVSVRRHLPGFTFLPR--IIQCLFLSSVITMILLTILSVTLDPPQKLPDLFSVLICFVSCVNFVFFLVYFNIVIMWDSKNGRNRKKID", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TAE8-1", "uniprot_id": "ALG6_MOUSE", "id": "Q3TAE8-1", "name": "Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase", "aln": "-------------MESWPWMAV-------------------VVLLGLTVRWTVSLSSYSGAGKPPMFGDYEAQRHWQEITLNLPVKQWYFNSSDNNLLYWGLDYPPLTAYHSLLCAYVAKFINPDWVALHTSRGYES--QAHKLFMRATVLAADLLIYVPAVLLYCYSLKEIS---PKRKIASALCILLYPGLILIDYGHFQYNSVSLGFALWGVLGVSWDWDLLGSLAFCLALNYKQMELYHSLPFFCFLLGKCFKKGLKGKGLALFIRIACTVLASFLLCWLP--FLTE-REHALQVVRRLFPVDRGLFEDKVANIWCSVNVFLKIKDTLPRHIQIAISFCFTLLSLLPACIKLTVRPSCKGFRFTLVSCALSFFLFSFQVHEKSILLVSLPVCLVLT----EIPFMSTWFLLVSTFSMLPLLLKDELLLPSVVTVMAFVIACGTFFPMLENTSEEQLQLKSFAVSVRRHLPGFTFLPR--IMQCLFLSSVITMVLLTILSVTLDPPQKLPDLFPVLICFVSCVNFVFFLVYFNIVIMWDSKNGRNRKKIE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y672-1", "uniprot_id": "ALG6_HUMAN", "id": "Q9Y672-1", "name": "Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase", "aln": "-------------MEKWYLMTV-------------------VVLIGLTVRWTVSLNSYSGAGKPPMFGDYEAQRHWQEITFNLPVKQWYFNSSDNNLQYWGLDYPPLTAYHSLLCAYVAKFINPDWIALHTSRGYES--QAHKLFMRTTVLIADLLIYIPAVVLYCCCLKEIS---TKKKIANALCILLYPGLILIDYGHFQYNSVSLGFALWGVLGISCDCDLLGSLAFCLAINYKQMELYHALPFFCFLLGKCFKKGLKGKGFVLLVKLACIVVASFVLCWLP--FFTE-REQTLQVLRRLFPVDRGLFEDKVANIWCSFNVFLKIKDILPRHIQLIMSFCSTFLSLLPACIKLILQPSSKGFKFTLVSCALSFFLFSFQVHEKSILLVSLPVCLVLS----EIPFMSTWFLLVSTFSMLPLLLKDELLMPSVVTTMAFFIACVTSFSIFEKTSEEELQLKSFSISVRKYLPCFTFLSR--IIQYLFLISVITMVLLTLMTVTLDPPQKLPDLFSVLVCFVSCLNFLFFLVYFNIIIMWDSKSGRNQKKIS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58JR12-1", "uniprot_id": "A0AC58JR12_DANRE", "id": "A0AC58JR12-1", "name": "Alpha-1,3-glucosyltransferase", "aln": "-MNSDDTSVSGGCCENYLLLPVKKQDE-----------DAILCRINIIRRSLYPFIYERCAGKPPMFGDYEAQRHWQELTYNLPVHEWYFNTTNNDLNYWGLDYPPLTAYHSLACAYIAKLFNPEWVELHASRGYES--HSHKLFMRATVLFADALIYIPAVLLYCFYFCDGS---PKQKVATAFCILMYPGLMLIDYGHFQYNGVSLGLALWGVLGLGLGWDLFGSVAFVLALNYKQMELYHALPFFCYLLGKCVKHGLNGQGFFHLVKISLTVLVTFALCWMP--FLSD-PKQPLQVLHRLFPVGRGLFEDKVANTWCSLNVLIKIKTLLSRETQLFLSFALTVLFVLPSSLKLLSKPTLWQFKLALVNSSLAFFLFSFQVHEKSILLAALPVCLVIN----EMPLIAVWFLLTSTFSMLPLLLKDGLLLPYVVTSLAFLFLSLYLLSALERSTDEELRLAPYRKLTQHFLPKLN-LSR--IVKWKFWLSLVAMAALSITSVWLEPPAKLPDLFPVLVSIFSFLHFLGFVIYFNLVQLMEPQRRKNQKKTN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VKX7-1", "uniprot_id": "ALG6_DROME", "id": "Q9VKX7-1", "name": "Probable dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase", "aln": "-------------MRSEILASA---------------------FLGLAVRSIISLYSYSGFDSPPMHGDYEAQRHWQEITVNLAVGEWYTNSSNNDLQYWGLDYPPLTAYHSYLVGRIGASIDPRFVELHKSRGFES--KEHKRFMRATVVSADVLIYLPAMLLLAYSLDKAFR--SDDKLFLFTLVAAYPGQTLIDNGHFQYNNISLGFAAVAIAAILRRRFYAAAFFFTLALNYKQMELYHSLPFFAFLLGECVSQKSFASFIAEISRIAAVVLGTFAILWVP--WLGS-LQAVLQVLHRLFPVARGVFEDKVANVWCAVNVVWKLKKHISNDQMALVCIACTLIASLPTNVLLFRRRTNVGFLLALFNTSLAFFLFSFQVHEKTILLTALPALFLLK----CWPDEMILFLEVTVFSMLPLLARDELLVPAVVATVAFHLIFKCFDSKSKLSNEYPLKYIAN-------------------------ISQILMISVVVASLTVPAPTKYPDLWPLIISVTSCGHFFLFFLWGNVQQFSSKLS--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12001-1", "uniprot_id": "ALG6_YEAST", "id": "Q12001-1", "name": "Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase", "aln": "MAIGKRLLVNKPAEESFYASPMYDFLYPFRPVGNQWLPEYIIFVCAVILRCTIGLGPYSGKGSPPLYGDFEAQRHWMEITQHLPLSKWYWY----DLQYWGLDYPPLTAFHSYLLGLIGSFFNPSWFALEKSRGFESPDNGLKTYMRSTVIISDILFYFPAVIYFTKWLGRYRNQSPIGQSIAASAILFQPSLMLIDHGHFQYNSVMLGLTAYAINNLLDEYYAMAAVCFVLSICFKQMALYYAPIFFAYLLSRSLLFPKFN--IARLTVIAFATLATFAIIFAPLYFLGGGLKNIHQCIHRIFPFARGIFEDKVANFWCVTNVFVKYKERFTIQQLQLYSLIATVIGFLPAMIMTLLHPKKHLLPYVLIACSMSFFLFSFQVHEKTILIPLLPITLLYSSTDWNVLSLVSWINNVALFTLWPLLKKDGLHLQYAVSFLLSNWLIGNFSFITPRFLPKSLTPGPSISSINSDYRRRSLLPYNVVWKSFIIGTYIAMGFYHFLDQFVAPPSKYPDLWVLLNCAVGFICFSIFWLWSYYKIFTSGSKSMKDL---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. . : * : ..**:.**:****** *:* :*.: :** :* ***********:** . :. ::* :. *. ***:** : * :**:**: :* *:*.**:: : . : : *. *** ******.: **:: .: : .:. * *:: :*** **:: **.:**.... : :: .: :* : : * :: : * ::*:**. **:******* ** **. * * :. . .: *.: **: : : . : .*. :::***********:**: ** :: . : .: *:: *** :* * : .*: : * . : : * . : .* * ***: :: . . * * :: : . ", "identical_positions": 126, "similar_positions": 125, "identity": "22.78%" }, { "cls_id": "homologset.agr.RGD:1308816", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8N9A8-1", "uniprot_id": "NEPR1_HUMAN", "id": "Q8N9A8-1", "name": "Nuclear envelope phosphatase-regulatory subunit 1", "aln": "MNSLEQAEDLKAFERRLTEYIHCLQPATGRWRMLLIVV----SVCTATGAWNWLIDPETQKVSFFTSLWNHPFFTISCITLIGLFFAGIHKRVVAPSIIAARCRTVLAEYNMSCDDTGKLILKPRPHVQ---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3UJ81-1", "uniprot_id": "NEPR1_MOUSE", "id": "Q3UJ81-1", "name": "Nuclear envelope phosphatase-regulatory subunit 1", "aln": "MNSLEQAEDLKAFERRLTEYIHCLQPATGRWRMLLIVV----SVCTATGAWNWLIDPETQKVSFFTSLWNHPFFTISCITLIGLFFAGIHKRVVAPSIIAARCRTVLAEYNMSCDDTGKLILKPRPHVQ---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GM63-1", "uniprot_id": "A0A8I6GM63_RAT", "id": "A0A8I6GM63-1", "name": "Nuclear envelope phosphatase-regulatory subunit 1", "aln": "MNSLEQAEDLKAFERRLTEYIHCLQPATGRWRMLLIVV----SVCTATGAWNWLIDPETQKVSFLTSLWNHPFFTISCITLIGLFFAGIHKRVVAPSIIAARCRTVLAEYNMSCDDTGKLILKPRPHVQ---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q561X0-1", "uniprot_id": "NEPR1_DANRE", "id": "Q561X0-1", "name": "Nuclear envelope phosphatase-regulatory subunit 1", "aln": "MNSLEQAEDLKAFERRLTEYVSCLQPATGRWRMILIVV----SVCTATGAWNWLIDPDTQKVSFFSSLWNHPFFTISCVTLIGLFFAGIHKRVVAPSIIAARCRTVLAEYNMSCDDTGKLILKPRPHIQ---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8T0B1-1", "uniprot_id": "NEPR1_DROME", "id": "Q8T0B1-1", "name": "Nuclear envelope phosphatase-regulatory subunit 1 homolog", "aln": "MEP-SACEDLKAFERRLTEVVSSYRPSTFRWRKLLAVVLSAMSMCTAISAWYWLRDPRTTVVPLTESLWIHPVFTVATLTLVVLFILGIQKLVIAPQIITSRTRMVLGDFNMSCDDTGKLILKPRQSNNNST", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q5LJU1-1", "uniprot_id": "Q5LJU1_DROME", "id": "Q5LJU1-1", "name": "Transmembrane protein 188", "aln": "-MEDTDQEDLLAFERRLAEVVNTEKRSSLRWRFVLGAI----FACSAISACHWVRDAKESESVVFQILSSQSAFAFSLATICLLIFYGFNHATKQDPSILRDTQEMLSPFRLNIDNQGRLILLPRQTE----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *** ******:* : : :: *** :* .: *:* .* *: *. . * :. *:.: *: *:: *::: . * : :*. :.:. *: *:*** ** ", "identical_positions": 33, "similar_positions": 34, "identity": "25.0%" }, { "cls_id": "homologset.agr.RGD:1308817", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q4V8D6-1", "uniprot_id": "BRF2_RAT", "id": "Q4V8D6-1", "name": "Transcription factor IIIB 50 kDa subunit", "aln": "MPNGSRCPDCGSSELVEDSHYSQSQLVCSDCGCVVTEGVLTTTFSDEGNLREVTYSRSTGENEQVSRSQQRDLRRVRDLCRILKLPLTFEETAVSYYQKAYQLSGIRAARLQKKEVVVGCCVLITCRQHNWPLTMGAICTLLYADLDVFSSTYMQIVKLLGLDVPSLCLADLVKSYCSSFKLFQASPSMPAKYVEDKDKMLSRTLLLVELANETWLVTGRHPLPIITAATFLAWQSLRPSDRLTCSLARFCKLANVDLPYPAAS------RLQELLAVLLQMASQLAWLQVLRLDKRSVVKHIGDLLQHRHMLVRMAFQDGTAEVETKQQQPQ----GRGQQEEVGDSTFDLPKRKRP---------ASPALLLPPCMLKPPKRTHTMPPDSVVTGDEDISDSEIEQYLRTPQEVRDFERAQAASRAAMSVPNPP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UAW9-1", "uniprot_id": "BRF2_MOUSE", "id": "Q3UAW9-1", "name": "Transcription factor IIIB 50 kDa subunit", "aln": "MPNGSRCPDCGSSELVEDSHYSQSQLVCSDCGCVVTEGVLTTTFSDEGNFREVTYSRSTGENEQVSRCQQRDLRRVRDLCRILKLPLTFEDTAISYYQKAYQLSGIRAARLQKKEVLVGCCVLITCRQHNWPLTMGTICTLLYADLDLFSGTYMQMVKLLGLDVPSLCLADLVKSYCSSFKLFQASPSVPAKYVEDKDKMLSRTLLLVELADETWLVTGRHPLPIITAATFLAWQSLRPSDRLTCSLAQFCKLANVDLPYPAAS------RLQELLAVLLQMAGQLAWLQVLKLNKRSVVKHIGDLLQHRHMLVRTAFRDGTAEVETQQQQQQQQGQGQGQQDEVGDGPFDLPKRKRR---------ASPTPLLPPCMLKPPKRTHTLPPESAVTGDEDISDSEIEQYLRTPQEVRDFERAQAASQAAMRVPNPP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HAW0-1", "uniprot_id": "BRF2_HUMAN", "id": "Q9HAW0-1", "name": "Transcription factor IIIB 50 kDa subunit", "aln": "MPGRGRCPDCGSTELVEDSHYSQSQLVCSDCGCVVTEGVLTTTFSDEGNLREVTYSRSTGENEQVSRSQQRGLRRVRDLCRVLQLPPTFEDTAVAYYQQAYRHSGIRAARLQKKEVLVGCCVLITCRQHNWPLTMGAICTLLYADLDVFSSTYMQIVKLLGLDVPSLCLAELVKTYCSSFKLFQASPSVPAKYVEDKEKMLSRTMQLVELANETWLVTGRHPLPVITAATFLAWQSLQPADRLSCSLARFCKLANVDLPYPASS------RLQELLAVLLRMAEQLAWLRVLRLDKRSVVKHIGDLLQHRQSLVRSAFRDGTAEVETREKEPPGWGQGQGE-GEVGNNSLGLPQGKRP---------ASPALLLPPCMLKSPKRICPVPPVSTVTGDENISDSEIEQYLRTPQEVRDFQRAQAARQAATSVPNPP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8KBY2-1", "uniprot_id": "BRF2_DANRE", "id": "A8KBY2-1", "name": "Transcription factor IIIB 50 kDa subunit", "aln": "--MSKNCPECGSSRVVEDDLYSQKQWVCEDCGSVVSEGLLTTTLSEESHSRAVPFFTSTAAFKKPCRNLVSGFSRLRALCRIFRLSSSMEDASANLFERAYNHPNFLHISLSKKQILAGCCMFHICRQNSWPVFMGTIGYLLDADNYQMGTIYQELTKSLNLQTTQVCITRMLESFCYDFKLAPD--EVEEVFSVAQQRLVDQTSALLELAADTWILTGRRPFPLFLAAVYVAWQSLNPLARMKYSLMKFCKIAKAPEQLWCKSKDTINKRLNELLEVLCKLGRELPWVRPTDIQMNTVTTLVEDILKHRKALLILAVKHYEKQLEETQTSQYSESELSDSKSSVQTQCKSPPDEEDEGCELPPDHWGKRHLFLPPCVRTQKRQKINEAP-LEVTGDEDISDSEIESYIRSEEEIKLFAKARKKICKY-------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .**:***:.:***. ***.* **.***.**:**:****:*:*.: * *.: **. :: .* .: *:* ***:::*. ::*::: :::**. ..: *.**:::.***:: ***:.**: **:* ** ** :. * ::.* *.*:...:*:: :::::* .*** .: : :::::.:* *:*** :**::***:*:*:: **.::*****.* *:. ** :***:*:. . * **:*** ** ::. :*.*:: :: .:*.. : *:*:**: *: *.:. ::* : . .. .* . *. : .. :****: . :: .* *****:*******.*:*: :*:: * :*: ", "identical_positions": 137, "similar_positions": 148, "identity": "31.49%" }, { "cls_id": "homologset.agr.RGD:1308818", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0JLY1-1", "uniprot_id": "CF210_MOUSE", "id": "A0JLY1-1", "name": "Cilia- and flagella- associated protein 210", "aln": "------MQVRFGRRSGQAKESQGMDCFEKEEIPYPPLLPSKVDLQQITIIPHAEWERIRDSLNRLTREAAVLRAERAAKKKMHVKSQELVKHWTNTYAGMKEQKLKAKQKRDEEIEAERKVLDLEEEIYKEGERKKAIESARQCQFHQTERVKRFHSGLLLSRVMKERDVQIQYKKNAVKSDKKWEEQVKLNDEKAFKEDQEKEEKRRRERVALAEDHLKQIEEHKEEEEARKKSEEKDAEEMKRQNLLYEIEMKKNLSKKQEEIDTNRKLLLDNMHNKNIIRAVEQQQQEEEDEKIRKFIKAKKRLIQMRMDKDAETHRLMEERRERINNFLSKLIKEKLDTEDLIIARDISEADAELEKREKEKHEKNQADLKAIAEYRASVMKNKEEEERQRKIEAKEQLQAVLKADKIFQELEKEKSLKVTREKLEIQDAHIQQIAINKYNAKQMKEEELDYWRLTDALTVEKEKEFEKYAREVINFESESTKKYAYPMVKAVQEGVGGGRGPPFVGRGGIRPSYQATDATGVQLPCFKSQGSKYNDFQKSKRRLGFTW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0L0L6-1", "uniprot_id": "A0ABK0L0L6_RAT", "id": "A0ABK0L0L6-1", "name": "", "aln": "------MQVRYGRRSGKAKERAGMESYEKEEIPYPPLLPSTVDLQQVTIIPHAEWERIRDSLNKLTREAAVLRAERTAKKNMHMKSQELVKHWTNTYAGMKEQKLRAKQKRDEELEAERQILDLEEEIYKQGERKKAIENAKQYQFYQTERVKRFHSGLLLSRVMKERDVQIQYKKNAVKSDEKWEEQVKLNDAKALKEDQEKLEKQRRERVALAKDHLKQIKEHEEEEETRKKSEEKDAEEIKRQNLLYEIEMKKKLSRKQEEIDASRKRFFDNMRDKNIIRAVEQQQQEEEEEKTRKFIKAKKRLIQMRKDKEAETHRLMEERRERINNFLSKLIKEKLDTEDLIMSRDIADIDTELDKREKEKHEKMQADLKAIAEHRASVMKNKEEEEKQRKIESKEELQAVLKADKMFQELEKEKKLKANKEKLEVQDAHIHQIALNKFNSKQLKEEDLNYWRLTEALAVEKEKEFEKYAREVINFESESTKKYTYPMVKAVQEGVGGGRGPPFVGRGGIRPSYQANDVTGVQLPFYNSQGSKY-DFQKSKRRLGFTW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q0VFZ6-1", "uniprot_id": "CF210_HUMAN", "id": "Q0VFZ6-1", "name": "Cilia- and flagella- associated protein 210", "aln": "MDTSSEMLVRFGRRCGRAKESTEIRNSEEDQVLYLPLLPSKVDLQQVTIIPHDEWKRIQDSLDRLTREAACLRAERKAKKEMHLRSQEVVKHWTNTYAGMKEQKLEAKKKRDEEIEAERQILDLEEEIYKQGKRKKAIENAKQYQFYQTERVKNFHSGLLLSRVMKERDAQIEFRKSKIKSDKKWEEQLKLNIEKAFKEEQEKAEKRHRERVALAKDHLKQIKEHEEEEERRKKYEEKDAEEIKRQNALYEIEMRKKLEKKREEMHESRRRFLEHMQDKHIIKAVEQQQQEEEDEKMRKFIKAKKRLIQMGKEKEAETHRLMEKRRERIHNFLSELLKEKLDNEDMIIARDIAEAEAEWEKREREKDEKNKAELKTIAEYRAIVMKNKEEEERQRKIEAKEQLLAVMKADQIFWEHEKEKKCKADKEHQEVQDAHIQQMAKNKFNAKQAKQAELDYCRLTEALVAEKEKEFQDYAREVIELESETTNKYIYPLVKAVQEGPGGGRGPVFVDRGGLRPSYQANDVTGVQLPFYNSQGPKY-NFQKSKRRLGFTW", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 383, "similar_positions": 120, "identity": "69.26%" }, { "cls_id": "homologset.agr.RGD:1308820", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K0F4-1", "uniprot_id": "A0A0G2K0F4_RAT", "id": "A0A0G2K0F4-1", "name": "", "aln": "MELKVWVDGVQRIVCGVTEVTTCQEVVIALAQAIGRTGRYTLIEKWRDTERHLAPHENPIVSLNKWGQYASDVQLILRRTGPSLSERP---------------------------TSDSVARIPERTLYRQS--------------------------------------------------LPPLAKLRPQVDKSIRRREPKRKS-------LTFTGG-----AKGLTDIFGKGKE------------------------------------------------------------------------------------------------TEFRQKVLSNCR------------------ATAEELTRLIRLQTGKLQAIEKQLESSEAEIRFWEQKYS------CSLEEEIVRLEQRIKRNDVEIEEEEFWENELQIEQENEKQLQDQLEEMRQKVADCEGRLKDYLAQIHTMESGLQAEKLHREVQEAQVNEEEVKGKIEKVKGEVDLQGQQSLRLENGIRAVARSLGQATKRLQDKEQELEQLTKELRQVNLQQFIQQTGTKVTVLPAEPTEIEASQADIETEAPFPSGSLKRPGSSRQLPSNLRILQNPVSSGFNPEGIYV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CJ96-1", "uniprot_id": "RASF8_MOUSE", "id": "Q8CJ96-1", "name": "Ras association domain-containing protein 8", "aln": "MELKVWVDGVQRIVCGVTEVTTCQEVVIALAQAIGRTGRYTLIEKWRDTERHLAPHENPIVSLNKWGQYASDVQLILRRTGPSLSERP---------------------------TSDSVARIPERTLYRQS--------------------------------------------------LPPLAKLRPQADKSIRRREPKRKS-------LTFTGG-----AKGLTDIFGKGKE------------------------------------------------------------------------------------------------TEFRQKVLSNCR------------------ATAEELKRLIRLQTGKLQAIEKQLESSEAEIRFWEQKYS------CSLEEEIVRLEQRIKRNDVEIEEEEFWENELQIEQENEKQLQDQLEEIRQKVTDCEGRLKDYLAQIHTMESGLQAEKLHREVQEAQVNEEEVKGKIEKVKGEMDLQGQQSLRLENGIRAVERSLGQATKRLQDKEQELEQLTKELRQVNLQQFIQQTGTKVTVLPAEPTEIEASQADIETEAPFQSGSLKRPGSSRQLPSNLRILQNPVSSGFNPEGIYV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NHQ8-1", "uniprot_id": "RASF8_HUMAN", "id": "Q8NHQ8-1", "name": "Ras association domain-containing protein 8", "aln": "MELKVWVDGVQRIVCGVTEVTTCQEVVIALAQAIGRTGRYTLIEKWRDTERHLAPHENPIISLNKWGQYASDVQLILRRTGPSLSERP---------------------------TSDSVARIPERTLYRQS--------------------------------------------------LPPLAKLRPQIDKSIKRREPKRKS-------LTFTGG-----AKGLMDIFGKGKE------------------------------------------------------------------------------------------------TEFKQKVLNNCK------------------TTADELKKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYN------SNLEEEIVRLEQKIKRNDVEIEEEEFWENELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKLQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLTKELRQVNLQQFIQQTGTKVTVLPAEPIEIEASHADIEREAPFQSGSLKRPGSSRQLPSNLRILQNPISSGFNPEGIYV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VBP2-1", "uniprot_id": "Q9VBP2_DROME", "id": "Q9VBP2-1", "name": "", "aln": "MELKVWVEGIQRIVCGVTVNTTCQDVVFALAHATGKVGRFTLIERWRNNERHLAPNENPMKLLLKWGEYANDVQFILQRSENKTQQQQQQQQQQQQNNNNNNNYAVMTTTKKPLGPNNNNNNKPAPTLLKQKSNVELSYRTKELKKSFGGHDAKQFDNIGIVKGIPQQQQLQSQQTAMGAPASPPQEQLTPQDNNNVAPLVPKHEKSLSNPLDMTSTGSNPPAPTNGYNDFYNNNSSSNQHIYSQLSKSSNELRRSSPNEMYYNNNNNIVNNNNNSPELYKQTPTISANGALVPPPYRDPPPPRNSPMCQGQRLASSNADTMSNASSSTNPFLSDYDQHSSHNTNSINNNSQAMEEGEPMFQTTQYNDLLQLIKFQREKITAQQMELQKFDTEIVYLESKERDHAHELDAISREISKADQIFRQGSEQLQTLQYVEEENELVKQQEKTLKSEIALLRSKLANCETELLQCKNKMRLLMDDIELEQQHQQQTNRQTVERDFLMEMERIQSEIDQALHNTDTSNKTADSLKKELLMIEHAIADKKRQVEQLVNEMKEVNLQSLTVTTTEEIKHLLEGP---------------------NKQGSSRRIIGSPRQLETAVPTSKNPHGVWV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*******:*:******** ****:**:***:* *:.**:****:**:.******:***: * ***:**.***:**:*: . .:: ..:. . * ** :*. ** :* ** ::.: **::. :* **. ::* *::.:... ::: *: * . : ::* :**::* *: : : :*:. : ** : *.* :..** : :* :::.. ::: :: *:* :: :::** *:.:: :*.*:::** .* : ::: : ..:: *: ::: : *. *.:. :: :::.*:* ::: :: :: :.* : : **::::***.:*:::****.: * ::. * * :: ****:: .. * *:..:.:. **.*::*", "identical_positions": 126, "similar_positions": 165, "identity": "20.06%" }, { "cls_id": "homologset.agr.RGD:1308821", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9V7S5-1", "uniprot_id": "PICO_DROME", "id": "Q9V7S5-1", "name": "Putative inorganic phosphate cotransporter", "aln": "-----MPFRRSSLNHRHRDGHVLVWNQRNLHESLEQQPQRCFATRYFVTFMLFLGMANAYVMRTNMSVAIVAMVNHTAIKSGEAEEYD------DECGDRDIPIDDSQDGEFAWSSALQGYILSSFFYGYVITQIPFGILAKKYGSLRFLGYGMLINSVFAFLVPVAARGGGVWGLCAVRFIQGLGEGPIVPCTHAMLAKWIPPNERSRMGAAVYAGAQFGTIISMPLSGLLAEYGFDGGWPSIFYVFGIVGTVWSIAFLIFVHEDPSSHPTIDEREKKYINDSLWGTD------VVKS-PPIPFKAIIKSLPFYAILFAHMGHNYGYETLMTELPTYMKQVLRFSLKSNGLLSSLPYLAMWLFSMFISVVADWMISS-KRFSHTATRKLINSIGQYGPGVALIAASYTGC---DRALTLAILTIGVGLNGGIYSGFKINHLDLTPRFAGFLMSITNCSANLAGLLAPIAAGHLISDPSKPMMGQWQIVFFIAAFVYIICGTFYNIFGSGERQYWDNPEDDEQKPALQTTVTTSPARLSNGSTAPAAISSS-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W4G7-1", "uniprot_id": "Q9W4G7_DROME", "id": "Q9W4G7-1", "name": "Putative inorganic phosphate cotransporter", "aln": "MTDTAGVYDSKGVSNRNRSDQEVRMER---YASDGQIP-RCRKTRFFVVLMLFSGMANAYVMRTNMSVAIVAMVNHTAISHTKSSTQS------KER-----------DGDFEWSYKLQGYILSSFFYGYVITQIPFGLMIKYYGARHFLGWGMMINSLAAFFIPISARSGGVVGLCVVRFIQGLGEGPIVPCSHSLLAQWVPPNERSLAGAAVYAGAQFGTIVSMPLSGLLAHYGFDGGWPSIFYIFGLFSTIWCIIFICLVQESPAVSTRISEAERRHIMEAIWQAQ------PEER-SRIPFLGIAKSPPFYAILVAHAGHNYGYETLMTMLPTYMYRVLNVNIRTNGIISSLPYLAMWILAIVFGILADCLIR--RNFSITVVRKLMNSLGQYGPAVALISVGFVHH---SLWLTSVIFILGMGLNGAIYCGFKINHLDLSPRFAGLLISVTNCVANLVGLMAPMVAGHVID--PKPSVENWRIVFYIAAGVFIFTASFYNVFASGKQQW--------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "D4A3I8-1", "uniprot_id": "D4A3I8_RAT", "id": "D4A3I8-1", "name": "", "aln": "---------------------------MDEKPTTRKGSGFCS-LRYALALVMHFSNFTMITQRVSLSIAIIAMVNSTQHQDPANASAEGPVMNLLSNRSRGIKDFSTRAAVYQWSTETQGIIFSSISYGIILTLIPSGYLAGIFGAKQILGAGLLISSLLTLFTPLAADFG-VILVIVIRTVQGMAQGMSWTGQFTIWAKWAPPLERSKLTSIAGSGAAFGSFIILCVGGLISQA---LGWPFIFYIFGSIGCVCCVLWFTMIYDDPMHHPCISVKEKEYITSSVAQQS------SSPR-RSIPIKAMVRCLPLWAIFMGFFSHFWLCTIIITYLPTYISTVLHVNIRDSGVLSSLPFIAASSCTILGGQMADFLLSR-NLLSLITVRKLFSSLGLLLPSLCAVALPFVTS---SYIATIVLLILIPGTSNLCDSGFIINTLDVAPRYASFLMGISRGFGLTAGIISSTTTGFLIS---QVG----------------------HVIEHLQVAGF-------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5SZA1-1", "uniprot_id": "NPT3_MOUSE", "id": "Q5SZA1-1", "name": "Sodium-dependent phosphate transport protein 3", "aln": "---------------------------MDEKPTTRKGSGFCS-LRYALALIMHFSNFTMITQRVSLSIAIIAMVNSTQHQDPANASTEGPVMDLLSNQSRGIKDFSTRAAVYQWSTETQGIIFSSISYGIILTLIPSGYLAGIFGAKQILGAGLLISSLLTLFTPLAADFG-VILVIVIRTVQGMAQGMAWTGQFTIWAKWAPPLERSKLTSIAGSGAAFGSFIILCVGGLISQA---LGWPFIFYIFGSIGCVCCVLWFTVIYDDPMHHPCISVREKEHITSSVAQQS------SSPR-RSVPIKAMVRCLPLWAIFMGFFSHFWLCTIIITYLPTYISTVLHVNIRDSGVLSSLPFIAASSCTILGGQMADFLLSR-NLLSLITVRKLFSSLGLLLPSLCAVALPFVTS---SYIATIVLLILIPGTSNLCDSGFIINTLDVAPRYASFLMGISRGFGLTAGIISSTTTGFLIS---QDSESGWRNVFFLSAAVNMFGLIFYLIFGQAEIQSWAKERTLTRL----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00624-1", "uniprot_id": "NPT3_HUMAN", "id": "O00624-1", "name": "Sodium-dependent phosphate transport protein 3", "aln": "---------------------------MDGKPATRKGPDFCS-LRYGLALIMHFSNFTMITQRVSLSIAIIAMVNTTQQQGLSNASTEGPVADAFNNSSISIKEFDTKASVYQWSPETQGIIFSSINYGIILTLIPSGYLAGIFGAKKMLGAGLLISSLLTLFTPLAADFG-VILVIMVRTVQGMAQGMAWTGQFTIWAKWAPPLERSKLTTIAGSGSAFGSFIILCVGGLISQA---LSWPFIFYIFGSTGCVCCLLWFTVIYDDPMHHPCISVREKEHILSSLAQQP------SSPG-RAVPIKAMVTCLPLWAIFLGFFSHFWLCTIILTYLPTYISTLLHVNIRDSGVLSSLPFIAAASCTILGGQLADFLLSR-NLLRLITVRKLFSSLGLLLPSICAVALPFVAS---SYVITIILLILIPGTSNLCDSGFIINTLDIAPRYASFLMGISRGFGLIAGIISSTATGFLIS---QVG----------------------PVY---------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N9Z0-1", "uniprot_id": "A0A8M1N9Z0_DANRE", "id": "A0A8M1N9Z0-1", "name": "Sialin", "aln": "-------MMELSASDSESEDHAQPLLRRKDTEDIQKAPACGS-SRYGLAFLSCYGFFVAYALRVNLSVAMVDMLKNSSK---ANTSSS-----ICPPHNIPVPKHNHTAMVYDWNSETQGWILGSFFYGYIITQIPGGYLARKYGAKWLLGLGILCTVIFTLLTPLAADLG-AGYLIAVRVLEGIGEGVTYPAMHAMWASWAPPLERSRLLTISYTGAQLGTVVALPLSGQICFY---LDWTYVFYIFGAVGLLWFFLWICFVSNSPSSHKRITEAEKTYIMSSLKNEL------SPTQ-DYIPWTSIFKSMPLWAIVVAHFSYNWTFYTLLTLLPTYMNDVLGFSIQQNGMLSALPYLGCWLLALLGGQLADLLRER-FLFRTVIVRKAFTVVGMAGPAVFLVAAGYTGC---NYILAVAFLTISSSLGGISASGFNINHLDIAPSYAGILLGITNSFATIPGMVGPVIARSLTK---SNTIPEWQIVFYISAAINIFGAVFFTIFGKGTVQPWAVQTIHIQ-----------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VR44-1", "uniprot_id": "Q9VR44_DROME", "id": "Q9VR44-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "-------------------------MSNTEKGGLQRVRNFLS-CRQVLNLLTMLGFMLNYALRVNLTIAIVDMVRPNVTSAVNATLVGN---STAANSTASPDGVDVYEERFPWDSYQTNFVLGCFFWGYILTELPGGRLAELIGGRRVFGHSMLWASLLTLITPLAAHIN-YVVLIVVRVVLGFMLGASWPAIHPVAAVWIPPMERSKFMSNMMAS-SLGAAITMPICGYLISV---AGWASVFYLTGAVGLLWSLAWFTFVYETPATHPRISAEERREIEEAIGTTT------SKKRPSHVPWGQLLCSPAVWAIIICHGLAVFGFFTVVNQLPTFMSKILHFDIKQNGLFSSLPYLGKYVMAVASSYLADYLRKK-GTLSTTATRKLFTTFALVIPGLLMIVQVFLGY---DATWSVTIFSLALFAHGAVTAGYLGNGLDIAPNFGGTIFGLANTLSSFGGFLSTSMVGALTYK--DQSFHSWQIVFWILAATYISAAVVFAILGSGELQPWNNPPERVRISDVTQEEGVPLKNEK-------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VKC9-1", "uniprot_id": "DMGLU_DROME", "id": "Q9VKC9-1", "name": "Dietary and metabolic glutamate transporter", "aln": "-------------------------MTQQPQWGISLSRYFVIPQRVILAIMGFLAILNAYTMRVCLSQAITVLVVKKNSTDDDSEAICE---------PDDIDEGTSVGGDFEWSEELQGLILSSFYIGYIVTHIPGGLLAEKFGGKWTLGLGILSTAVFTMLTPLAINKGDSDWLIVTRVLMGLGEGTTFPALSVLLAAWVPANERGKLGALVLGGGQVGTIMGNLLSGVFIDA---YGWEFVFYFFGGLGVVWFAIFMFLCYSDPTSHPFIKPSEREYLVKEIGTIS------RNEDLPPTPWKAILTNLPMFALVAAQIGHDWGFYIMVTDLPKYMADVLQFSIKANGLYSSLPYVMMWIVSVGSGFVADWMIRR-GVLSTTNTRKVMTGLAAFGPAIFMVGASYAGC---DRVLVVVLFTICMGLMGAYYAGMKLSPLDMSPNYAGTLMAITNGIGAITGVITPYLVGVMTP---NASLLEWRLVFWVAFGVLCFTAVIYCIWASGEVQPFNNAPIQPRSVDFEAQERKVGGEKTSGLEQSS------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W1Y9-1", "uniprot_id": "Q9W1Y9_DROME", "id": "Q9W1Y9-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "--------------------------MTIKSFNLVVKGPMWG-VRHLQVLFLFLCATLIVAQRFNMSVAIVAFTNANSSN--------------------------PNYPEYRLTEPQKSYTISSPFWGSCCTQMMSGYLSSRFGAKVLLLTIMLLTALLSIATPFALAWGGWQLLFWVRFVQGLAMGGMWPCLYTHLAKWCPKKEANRMGGIMTTGLDCGTIMGFALSGVLSASP--LGWPSTFYVPGYLGIVWCLTFLRYGANSPSESKFISLAERKHIQFALEQNQ-----VIRGATPPVPWLQILTSRPFIVLAFCKMSQACSFYTLMQQIPRYIHGIFHYSIAANALLSALPFVVMLMSSYGFIFLAEYLTRR-RDISLPILRKTINSFATWTPAVALVILSYVSD--QNVVGSMFCLIAATAAISGQAIGSSLNHVDLSPNFAGLLFGMSNTLMSAAGVISPIVIGLTVTK--ESDRSQWRTVFLGISVILFLGNLMYLIFGQMTVQSWNDSPSKETETEASPKPQASAPSVAEETISVERFNYL-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V9S4-1", "uniprot_id": "Q9V9S4_DROME", "id": "Q9V9S4-1", "name": "Putative inorganic phosphate cotransporter", "aln": "---------------------------MNDMEEIPKTVPRLG-LRHLQAGLLFYGLAANTVLQLNVSVAVVAMTNETTSNN-------------------------SDPPHYNWSEEKKSYILSSYYWGCALAQFPAGYLCKRFGSKAVLFWGTLGSSLLSALTTYGVYAGGWKAYCAIRLLQGLCQ-VTWPCIHQHLANWCPTAERTRLGAFAYTGFDCGNVLAMYGAGMIASSS--LGWPGISYSAAGLGLIWCGLWLLLGANKASDARFIGEAEKAYIVGDIQRSE-----RKGPKKMEIPWKGIFTSVPVYALLCARCADSWGLTTMQTELPTYLSGVLKLDMKSNAVFSALPFLLMWVMCYVYLIIADVLLRK-KWMSLTTLRKTYTSIALWAPASIMLSLVIVGE--GQKTLVLVLVTLSVGVSSAATIGSELNTIDLSPNHAGILAGLMSSFTNLMALLTPLVVGVLVTD--PSQRSQWQIVFSLAAGVLFTGNVIFLIWGTAVTQPWNESKESRRELEPEEKPFHRAKLEIGTDNTDGNVVGLKLNCTSP", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1ZBD9-1", "uniprot_id": "A1ZBD9_DROME", "id": "A1ZBD9-1", "name": "Putative inorganic phosphate cotransporter", "aln": "-----------------MVLGCLPCCNHNGYQQIGNTGPRFG-VRHLQCILVFFGLAVAYSLRVNLSVAIVAMTDRNASN--------------------------PDFPEFDWNESTKSYLLSSFFWGYVVTQIPGGYLSAIYGAKYMLFYGVLICSCLALLTPFCAVNGGWTVVVVLRAVQGLCQGVIFPSTHTFLSKWAPAEERGRLVGYTYSGSQFGTVVMLSVSGYIASSS--LGWPSTFYIPGCVGIVWSFVWLYLCSSTPAQHPTITPNERRFIESSGQARRPSDAGREEQPRPPTPWWRIFTSVPFLVLVLAHCANNWGFWTLLTEIPTFMKNVLGMDIKNNGPLSALPYFAMILLTCVFIWLSDTLKQRGTVIPLGFSRKFFNTLGMWLPMLALIGLGYITEGEANVRLAIGLLTAAVATNSATYLGFHVNHIDLSPNYAGTLMGITNCAANFMSILAPLIVGLIVWD--ETNPAQWRIVFFFTAFVYFIGNLLFMLFGRTRVQPWNSRPTTR-----TPSPGGGGERDEGTEDRGPLIGA--------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . : :: *: : . : . :.. * : : * : *. : : : . . * : *: . : * * * . * : * : .* * . . : :: . . * *: : * : .. .: : :* :: :: .: .. *:**:. ::: : : ** . .. * : . . . * . :*::* ... : .: ..: . : ", "identical_positions": 27, "similar_positions": 83, "identity": "4.84%" }, { "cls_id": "homologset.agr.RGD:1308822", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q0KL00-1", "uniprot_id": "PIEZ1_RAT", "id": "Q0KL00-1", "name": "Piezo-type mechanosensitive ion channel component 1", "aln": "MEPHVLGAGLYWLLLPCTLLAASLLRFNALSLVYLLFLLLLPWLPGPSRHSIPGHTGRLLRALLCLSLLFLVAHVAFQICLHTMPRLNQLLGQNCNLWANVSQHIGVTRLDLKDIFNTTRLVAPDLGVLVASSLCLGLCGRLTRKARQS---------QRTQELEEDD---------IDAAPAAGLQGAP--------------TLATKRRLWLAPRFRITAHWLLVTSGRMLVIVLLALAGIAHPSAFSSVYLMVFLAICTWWSCHFPLSSLGFNTLCVMVSCFGAGHLVCLYCYQTPFVQSVLLPGSLWARLFGLKNFVDI-PNCSSPNVLVLNTKHAWPIYVSPGILLLLYYTATSLLKLRKGRFSELRKE-------IPREDEEHELELDQLEPEPQA-RGTTQGATPTTTGPDIDNCTVHVLTSQSPVRQRPVRPRLAELKEMSPLHGLGHLILDQSYVCALIAMMVWSIMYHSWLTFVLLLWACLIWTVRSRHQLAMLCSPCILLYGLTLCCLRYVWAMEL--PELPTTLG--PVSLHQLGLEHTR----YPCLDLGAMLLYLLTFWLLLRQFVKEKLLKKRKAPSTLLEVTVSDTEPT-----------QTQTLLRSLGELVTGIYVKYWIYVCAGMFIVVSFAGR-LVVYKIVYMFLFLLCLTLFQVYYTLWRKLLRVFWWLVVAYTMLVLIAVYTFQFQDFPTYWRNLTGFTDEQLGDLGLEQFSVSELFSSILIPGFFLLACILQLHYFHRPFMQLTDLEHVPPPGTRRLRWAHRQDTVSEAPLLQHQ------------EEEEVFRDDGQSMDGPHQTTQVPEGTASKWGLVADRLLDLASSFSAVLTRIQVFVRCLLELHVFKLVALYTVWVALKEVSVMNLLLVVLWAFALP-YPRFRPMASCLSTVWTCIIIVCKMLYQLKIVNPHEYSSNCTEPFPNNTNLQPLEISQSLLYRGPVDPANWFGVRKGYPNLG----YIQNHLQILLLLVFEAVVYRRQEHYRRQHQ-QAPLPAQALCADGTRQRLDQDLLSCLKYFINFFFYKFGLEICFLMAVNVIGQRMNFMVILHGCWLVAILTRRRREAIARLWPNYCLFLTLFLLYQYLLCLGMPPALCIDYPWRWSQAIPMNSALIKWLYLPDFFRAPNSTNLISDFLLLLCASQQWQVFSAEQ--TEEWQRMAGVNTDHLEPLR-GEPNPIPN-----FIHCRSYLDMLKVAVFRYLFWLVLVVVFVTGATRISIFGLGYLLACFYLLLFGTTLLQKDTRAQLVLWDCLILYNVTVIISKNMLSLLSCVFVEQMQSNFCWVIQLFSLVCTVKGYYDPKEMKTRDRDCLLP-------VEEAGIIWDSICFFFLLLQRRVFLSHYFLHVSADLKATALQASRGFALYNAANIKNINFHRQTEERSLAQLKRQMKRIRAKQEKYRQSQASRGQLQ-STDPQ----EPGPDSPGGSSPPRTQWWRPWQDHATVIHSGDYFLFESDSEEEEEALP-----EDPRPAAQSAFQMAYQAWVTNAQTVLRQRR---EQARRDRAEQLAS-------------GGDLSPEVELVDVPENEMAGHSH---VMQRVLSTMQFLWVLGQATVDGLTRWLRTFTKDHRTMSDVLCAERYLLTQELLRGGEVHRGVLDQLYVSEDEIALSGPVENRDGPSTASSGLGAEEPLSSMTDDTGSPLSTGYNTRSGSEEIITDTGGLQAGTSLHGSQE-----------------LLANARTRMRTASELLLDRRLRIPELEEAEQFEAQQGRTLRLLRAMYQCVAAHSELLCYFIIILNHMVTASAASLVLPVLVFLWAMLTIPRPSKRFWMTAIVFTEVMVVTKYLFQFGFFPWNSYIVLRRYENKPYFPPRILGLEKTDSYIKYDLVQLMALFFHRSQLLCYGLWDHEEDGVPKDHCRSSEKDQEAEEESEAKLESQPETGTGHPEEPVLTGTPKDHIQGKGSVRSKDEIQDPPEDLKPQHRRHISIRFRRRK-ETQGPKGAAVVEAEHE-----EGEEGREAAGRKRLRRPREGLKIREKMKAAGRRLQSFCLSLAQSFYQPLRRFFHDILHTKYRAATDVYALMFLADIVDIVVIIFGFWAFGKHSAATD--IASSLSDDQVPQAFLFMLLVQFGTMVIDRALYLRKTVLGNLAFQVVLVVAIHLWMFFILPAVTERMFRQNAVAQLWYFVKCIYFALSAYQIRCGYPTRILGNFLTKKYNHLNLFLFQGFRLVPFLVELRAVMDWVWTDTTLSLSNWMCVEDIYANIFIIKCSRETEKKYPQPKGQKKKKIVKYGMGGLIILFLIAIIWFPLLFMSLIRSVVGVVNQPIDVTVTLKLGGYEPLFTMSAQQPSIVPFTPEDYEELSQQFDPYPLAMQFISQYSPEDIVTAQIEGSSGALWRISPPSRAQMKHELYNGTADITLRFTWNFQRDLAKGGSVEYTNEKHTLELAPNSTARRQLAQLLEGRP-------------------DQSVVIPHLFPKYIRAPNGPEANPVKQLQPDEEEDYLGVRIQLRREQVGTGTSGEQAGTKASDFLEWWVIELQDCQAECNLLPMVIFSDKVSPPSLGFLAGYGIVGLYVSIVLVVGKFVRGFFSDISHSIMFEELPCVDRILKLCQDIFLVRETRELELEEELYAKLIFLYRSPETMIKWTREKE------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E2JF22-1", "uniprot_id": "PIEZ1_MOUSE", "id": "E2JF22-1", "name": "Piezo-type mechanosensitive ion channel component 1", "aln": "MEPHVLGAGLYWLLLPCTLLAASLLRFNALSLVYLLFLLLLPWLPGPSRHSIPGHTGRLLRALLCLSLLFLVAHLAFQICLHTVPHLDQFLGQNGSLWVKVSQHIGVTRLDLKDIFNTTRLVAPDLGVLLASSLCLGLCGRLTRKAGQS---------RRTQELQDDDDDDDDDDEDIDAAPAVGLKGAP--------------ALATKRRLWLASRFRVTAHWLLMTSGRTLVIVLLALAGIAHPSAFSSIYLVVFLAICTWWSCHFPLSPLGFNTLCVMVSCFGAGHLICLYCYQTPFIQDMLPPGNIWARLFGLKNFVDL-PNYSSPNALVLNTKHAWPIYVSPGILLLLYYTATSLLKLHKSCPSELRKE-------TPREDEEHELELDHLEPEPQA-RDATQGEMPMTTEPDLDNCTVHVLTSQSPVRQRPVRPRLAELKEMSPLHGLGHLIMDQSYVCALIAMMVWSIMYHSWLTFVLLLWACLIWTVRSRHQLAMLCSPCILLYGLTLCCLRYVWAMEL--PELPTTLG--PVSLHQLGLEHTR----YPCLDLGAMLLYLLTFWLLLRQFVKEKLLKKQKVPAALLEVTVADTEPT-----------QTQTLLRSLGELVTGIYVKYWIYVCAGMFIVVSFAGR-LVVYKIVYMFLFLLCLTLFQVYYTLWRKLLRVFWWLVVAYTMLVLIAVYTFQFQDFPTYWRNLTGFTDEQLGDLGLEQFSVSELFSSILIPGFFLLACILQLHYFHRPFMQLTDLEHVPPPGTRHPRWAHRQDAVSEAPLLEHQ------------EEEEVFREDGQSMDGPHQATQVPEGTASKWGLVADRLLDLAASFSAVLTRIQVFVRRLLELHVFKLVALYTVWVALKEVSVMNLLLVVLWAFALP-YPRFRPMASCLSTVWTCIIIVCKMLYQLKIVNPHEYSSNCTEPFPNNTNLQPLEINQSLLYRGPVDPANWFGVRKGYPNLG----YIQNHLQILLLLVFEAVVYRRQEHYRRQHQ-QAPLPAQAVCADGTRQRLDQDLLSCLKYFINFFFYKFGLEICFLMAVNVIGQRMNFMVILHGCWLVAILTRRRREAIARLWPNYCLFLTLFLLYQYLLCLGMPPALCIDYPWRWSKAIPMNSALIKWLYLPDFFRAPNSTNLISDFLLLLCASQQWQVFSAER--TEEWQRMAGINTDHLEPLR-GEPNPIPN-----FIHCRSYLDMLKVAVFRYLFWLVLVVVFVAGATRISIFGLGYLLACFYLLLFGTTLLQKDTRAQLVLWDCLILYNVTVIISKNMLSLLSCVFVEQMQSNFCWVIQLFSLVCTVKGYYDPKEMMTRDRDCLLP-------VEEAGIIWDSICFFFLLLQRRIFLSHYFLHVSADLKATALQASRGFALYNAANLKSINFHRQIEEKSLAQLKRQMKRIRAKQEKYRQSQASRGQLQ-SKDPQDPSQEPGPDSPGGSSPPRRQWWRPWLDHATVIHSGDYFLFESDSEEEEEALP-----EDPRPAAQSAFQMAYQAWVTNAQTVLRQRR---ERARQERAEQLAS-------------GGDLNPDVEPVDVPEDEMAGRSH---MMQRVLSTMQFLWVLGQATVDGLTRWLRAFTKHHRTMSDVLCAERYLLTQELLRVGEVRRGVLDQLYVGEDEATLSGPVETRDGPSTASSGLGAEEPLSSMTDDTSSPLSTGYNTRSGSEEIVTDAGDLQAGTSLHGSQE-----------------LLANARTRMRTASELLLDRRLHIPELEEAERFEAQQGRTLRLLRAGYQCVAAHSELLCYFIIILNHMVTASAASLVLPVLVFLWAMLTIPRPSKRFWMTAIVFTEVMVVTKYLFQFGFFPWNSYVVLRRYENKPYFPPRILGLEKTDSYIKYDLVQLMALFFHRSQLLCYGLWDHEEDRYPKDHCRSSVKDREAKEEPEAKLESQSETGTGHPKEPVLAGTPRDHIQGKGSIRSKDVIQDPPEDLKPRHTRHISIRFRRRK-ETPGPKGTAVMETEHE-----EGE-GKETTERKRPRHTQEKSKFRERMKAAGRRLQSFCVSLAQSFYQPLQRFFHDILHTKYRAATDVYALMFLADIVDIIIIIFGFWAFGKHSAATD--IASSLSDDQVPQAFLFMLLVQFGTMVIDRALYLRKTVLGKLAFQVVLVVAIHIWMFFILPAVTERMFSQNAVAQLWYFVKCIYFALSAYQIRCGYPTRILGNFLTKKYNHLNLFLFQGFRLVPFLVELRAVMDWVWTDTTLSLSNWMCVEDIYANIFIIKCSRETEKKYPQPKGQKKKKIVKYGMGGLIILFLIAIIWFPLLFMSLIRSVVGVVNQPIDVTVTLKLGGYEPLFTMSAQQPSIVPFTPQAYEELSQQFDPYPLAMQFISQYSPEDIVTAQIEGSSGALWRISPPSRAQMKQELYNGTADITLRFTWNFQRDLAKGGTVEYTNEKHTLELAPNSTARRQLAQLLEGRP-------------------DQSVVIPHLFPKYIRAPNGPEANPVKQLQPDEEEDYLGVRIQLRREQVGTGASGEQAGTKASDFLEWWVIELQDCKADCNLLPMVIFSDKVSPPSLGFLAGYGIVGLYVSIVLVVGKFVRGFFSEISHSIMFEELPCVDRILKLCQDIFLVRETRELELEEELYAKLIFLYRSPETMIKWTRERE------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92508-1", "uniprot_id": "PIEZ1_HUMAN", "id": "Q92508-1", "name": "Piezo-type mechanosensitive ion channel component 1", "aln": "MEPHVLGAVLYWLLLPCALLAACLLRFSGLSLVYLLFLLLLPWFPGPTRCGLQGHTGRLLRALLGLSLLFLVAHLALQICLHIVPRLDQLLGPSCSRWETLSRHIGVTRLDLKDIPNAIRLVAPDLGILVVSSVCLGICGRLARNTRQS---------PHPRELDDDE-------RDVDASPTAGLQEAA--------------TLAPTRRSRLAARFRVTAHWLLVAAGRVLAVTLLALAGIAHPSALSSVYLLLFLALCTWWACHFPISTRGFSRLCVAVGCFGAGHLICLYCYQMPLAQALLPPAGIWARVLGLKDFVGP-TNCSSPHALVLNTGLDWPVYASPGVLLLLCYATASLRKLRAYRPSGQRKE-------AAKGYEARELELAELDQWPQE-RESDQHVVPTAPDTEADNCIVHELTGQSSVLRRPVRPKRAEPREASPLHSLGHLIMDQSYVCALIAMMVWSITYHSWLTFVLLLWACLIWTVRSRHQLAMLCSPCILLYGMTLCCLRYVWAMDLR-PELPTTLG--PVSLRQLGLEHTR----YPCLDLGAMLLYTLTFWLLLRQFVKEKLLKWAESPAALTEVTVADTEPT-----------RTQTLLQSLGELVKGVYAKYWIYVCAGMFIVVSFAGR-LVVYKIVYMFLFLLCLTLFQVYYSLWRKLLKAFWWLVVAYTMLVLIAVYTFQFQDFPAYWRNLTGFTDEQLGDLGLEQFSVSELFSSILVPGFFLLACILQLHYFHRPFMQLTDMEHVSLPGTRLPRWAHRQDAVSGTPLLREEQQEHQQQQQEEEEEEEDSRDEGLGVATPHQATQVPEG-AAKWGLVAERLLELAAGFSDVLSRVQVFLRRLLELHVFKLVALYTVWVALKEVSVMNLLLVVLWAFALP-YPRFRPMASCLSTVWTCVIIVCKMLYQLKVVNPQEYSSNCTEPFPNSTNLLPTEISQSLLYRGPVDPANWFGVRKGFPNLG----YIQNHLQVLLLLVFEAIVYRRQEHYRRQHQ-LAPLPAQAVFASGTRQQLDQDLLGCLKYFINFFFYKFGLEICFLMAVNVIGQRMNFLVTLHGCWLVAILTRRHRQAIARLWPNYCLFLALFLLYQYLLCLGMPPALCIDYPWRWSRAVPMNSALIKWLYLPDFFRAPNSTNLISDFLLLLCASQQWQVFSAER--TEEWQRMAGVNTDRLEPLR-GEPNPVPN-----FIHCRSYLDMLKVAVFRYLFWLVLVVVFVTGATRISIFGLGYLLACFYLLLFGTALLQRDTRARLVLWDCLILYNVTVIISKNMLSLLACVFVEQMQTGFCWVIQLFSLVCTVKGYYDPKEMMDRDQDCLLP-------VEEAGIIWDSVCFFFLLLQRRVFLSHYYLHVRADLQATALLASRGFALYNAANLKSIDFHRRIEEKSLAQLKRQMERIRAKQEKHRQGRVDRSRPQDTLGPKDPGLEPGPDSPGGSSPPRRQWWRPWLDHATVIHSGDYFLFESDSEEEEEAVP-----EDPRPSAQSAFQLAYQAWVTNAQAVLRRRQQEQEQARQEQAGQLPT-------------GGGPSQEVEPAEGPEEAAAGRSH---VVQRVLSTAQFLWMLGQALVDELTRWLQEFTRHHGTMSDVLRAERYLLTQELLQGGEVHRGVLDQLYTSQAEATLPGPTEAPNAPSTVSSGLGAEEPLSSMTDDMGSPLSTGYHTRSGSEEAVTDPGEREAGASLYQG--------------------------LMRTASELLLDRRLRIPELEEAELFAEGQGRALRLLRAVYQCVAAHSELLCYFIIILNHMVTASAGSLVLPVLVFLWAMLSIPRPSKRFWMTAIVFTEIAVVVKYLFQFGFFPWNSHVVLRRYENKPYFPPRILGLEKTDGYIKYDLVQLMALFFHRSQLLCYGLWDHEEDSPSKEHDKSGEEEQGAEE------------GPGVP-----AATTEDHIQVEARVGPTDGTPEPQVELRPRDTRRISLRFRRRKKEGPARKGAAAIEAEDR-----EEEEGEEEKEAPTGREKRP-SRSGGRVRAAGRRLQGFCLSLAQGTYRPLRRFFHDILHTKYRAATDVYALMFLADVVDFIIIIFGFWAFGKHSAATD--ITSSLSDDQVPEAFLVMLLIQFSTMVVDRALYLRKTVLGKLAFQVALVLAIHLWMFFILPAVTERMFNQNVVAQLWYFVKCIYFALSAYQIRCGYPTRILGNFLTKKYNHLNLFLFQGFRLVPFLVELRAVMDWVWTDTTLSLSSWMCVEDIYANIFIIKCSRETEKKYPQPKGQKKKKIVKYGMGGLIILFLIAIIWFPLLFMSLVRSVVGVVNQPIDVTVTLKLGGYEPLFTMSAQQPSIIPFTAQAYEELSRQFDPQPLAMQFISQYSPEDIVTAQIEGSSGALWRISPPSRAQMKRELYNGTADITLRFTWNFQRDLAKGGTVEYANEKHMLALAPNSTARRQLASLLEGTS-------------------DQSVVIPNLFPKYIRAPNGPEANPVKQLQPNEEADYLGVRIQLRREQ-GAGATG---------FLEWWVIELQECRTDCNLLPMVIFSDKVSPPSLGFLAGYGIMGLYVSIVLVIGKFVRGFFSEISHSIMFEELPCVDRILKLCQDIFLVRETRELELEEELYAKLIFLYRSPETMIKWTREKE------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7TDV6-1", "uniprot_id": "A0A8N7TDV6_DANRE", "id": "A0A8N7TDV6-1", "name": "", "aln": "MELQVVCGLLYCCLLPIFLLAACIFRYNALSLVYLLYLLLLPWFQWPNKHTLRGHTGCYIKALFSTSLIFILGHVTFQICLYTIPSLDDALGHNCSSWETLSRHVGVSRLPLEDPQGVLWLLTPDLGVFIMSLITLILCSRLLKKRDEGSVPHMSALLHEADETEDDDE--DVEGEDEGMLSCSETEDEE--------------SPSSSSAAQLAARLRATAQRFLRNMGRILAVTLLALAGITLPSAFSAFYFLLFIGVCTWWACHFPISHLGFNALCVMVAFFTGGHLVCLYLYQSSFAQAMFSPAGLWARLFGLKDLVTP-GNCTT-FEVTLNTQYDWPVYVNPGILLLLYISVTIVLKINSNSLGDADKAREGEAVKTVQGEAGEEVELRLWEARRQSSEDDTKQTLLTTVDSTLSESHITKEPVINGSSQHDIGPS-GEATVDNPLRLVGRMVLQQSYICALIAMMVWSITYHSWLTFVLLLWSCVIWMLRTRQRFAAYCSPFILLYGLALCCLQYVWAMDLE-TELPQHIG--SMSLHQLGLDRAQ----YPCLRLGALLLFTLTFWLLLRQSVKDTFSRKKSLTVPLQEVTTGESTG------------RNESILKVFGGLVMSLYAKYWIYVCGGMFIMVSFAGK-LVAYKIVYMLLFLLCMCLYQVYYSLWRRLLKAFWWMVVAYTMVVLIAIYTFQFEDFPGYWGNFTGFTEQQLADMGLETFKLSELFTSIVIPGFFLLACILQLHYFHKPFMKITDLENVSP--------IHRKRGIDNPDLVQST-------------EEVRPEEEELIVDQDDYPSEADEVIPSKWGLVMDRLMVLSRKFSDTLTHVQSFIWRVLELHIVKIVAFFVVWVALLEPSAMNLVLVVLWSFAMP-YGRFRAMASCLSTIWVCVIIVCKMLYQLSVVNPAEYSNNCTAPMVNETSLEPDEVLNSTLYRASVDPASWFGVRKDDTVLG----YVKDHLLVLMLLVFEATVYRHQIHHYRQQQ-RSPPPIPVIFPQATRDTLDQGLLHCIKYMLNYSFYKFGLEICFLMTVNVIGQRMNFLVIIHGCWLVAIMVRRRRANIATIWSKYCLFLVVFMIYQYVLCVGIPPALCIDYPWRWRSTVTIHSALVKWMYLPDFYTVPNSKNLISDFLLLMCASQQWTVFDNEK--KEEWMVMGGENRDNPDPMENMLFNPAPN-----FINCRSYLDMAKILVFRYMFWFVLSVVFVTGATRISVFGLGYLMACFFFLLFGTKLLTKPSRTRLVMWDCLIIYNVAVIISKNILSILACVFVMEMQKNFCWVIQLFSLVCTVKGYYDPESVCN--KDCSLP-------VEEAGIIWDSICFFFLLLQRRVFLSFYFLHVSADLQASARQASRGFELFRASIIKNMHFHQQAERKSIQQLKESMKRIRGKQQKYKDGRITSDIEEQPSDPK----EQKKETKLSKS---KSWQYPWVDHATVLHSGEYYMFESDSGEEDETFQ-----EEQKPRRQTAFQLAYQAWVTSAKDALKERQQRQRKQRAEAEKQQNAQATDDAEEGETVFDGENSQHAEEMQEEGEDAASQATGSDMVQRILDILKFLWVLFLAMVDGFTMWLNLLTKQYVDTSMVLSEERYLFIHNVSQR-ASRENMDDQISHDSEDLTLETCLDETDTDNICDTNVVESETLGGFAKSR--DFSSTTLSSELTLELDCEPFYSQQTHRPHRS----------------------------RTASELLSERPFRVDELIQSREFYSSQNRLLKLLFALYNVLAAHSELVCYFIIVLNNLVTASVISLVLPVLVFLWAMLSVPRPSKRFWMTAIIYTEVMVVVKYLFQFGFFPWNTEYELKLNEDKPFFPPRILGLEKTDNYIRYDLLQLLVLFFHRSLLQRYGLWDQEGPLEEKSDLSPAENSKNENDE----------KKFQHSDEEDSQAQPEPNTEVLSLTPSAETPTDAEIQTDPEPNSHTNNTKTSDTVKNDGMKKSHFLRFRKKKKAEPDAVQKEPKKKKKKCKTKHSKETSKKLLNAIEGKFKSLFLSVVKNVYRPTWDFFQNILHAEYRASTDVYALMFLTDVVDFIIIIFGFWAFGKHSAAAD--IASSLSEDQVPEAFLVMLLIQFSTMIIDRALYLRKSILGKLIFQVILVFGIHLWMFFILPAVTERMFNHNSVAQLWYFFKCIYFTLSAYQIRCGYPTRILGNFLTKKFNHLNLFLFQGFRLVPFLVELRAVMDWVWTDTTLSLSNWMCVEDIYANIFIIKCSRETEKKYPQPKGQKKKRIVKYGMGGLIILFLICIIWFPLLFISLVKSVVGVVNHPVDVTVTVKLGGYEPLFTMSVQQQSIQPFTESRYNQLNNQFSKNAVAMQFITMYSYEDIVTANIEGSSGSVWRISPPSRQELIKELLSSTGDMTLRLDWNFQRDLGKGGTVENTFDKHSISLAPKNPVRADLASLLLGTR-------------------KDPVHVPHMFPNYIRAPSGAEAKPVMQLFDGDEEGFQDVTVSLMREA-SVNTTG---------AQEWWDISIADCKESCNVLPMIIFNDKVSPPSLGFLAGYGIMGLYVSVVLVIGKFVRGFFSEISHSIMFEELPCADRILKLCMDIFLVRETGELELEEELYSKLIFLYRSPETMIKWTREKNHN----------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9MSG8-1", "uniprot_id": "PIEZO_DROME", "id": "M9MSG8-1", "name": "Piezo-type mechanosensitive ion channel component", "aln": "MVFSYACMVLQRIVVPAVLVLAALMRPVGISFVYLLMFFVSPFVPLATRRNFKGSVTAFFIILLTLSTLVLLGHITLQILAVSLTLPI----YNCSFSERLLRHIGFVSFIDLQPFAIIEWLVPEVLVFATSLGSYLTVKRVASQ-------------PVGAEQLENGEVVDGQAENAQTSSQPSAADANGGDVQQATVTTPLQQQQQQLRKRVSMISQHIHFEGLVKISPLFCLATLFFAAVLRPSVPGGFYFLIFLLSGTYWATCQTL-QRGFALLLRCVMVVLVLHSLSIVSYQTPWMQSHLNHTTLTARLIGLEPLIESYCSP-DIRVFLYNNKLSLDSYLNPFALFFAYFALALTTKHLI------------------------KPRLVRQSTRKARTPQPLESGSSVAPSVTQRGNDMQLESMEQRSEQENTTTSILDQISYG-FVSVGGFIYQNSYIFTNILMMAWSIVYHSWLTFVLLLSANVLWMIPNQRKAMMRSSPFIVLYAEALLIAQYIYGMDLNNEELPTSVPTAGINLQQIGFERPIENQMRPCVPLIVKTAFVLMFWVTSRQFFKEKRDRRRDSTLADFIAPLQITVGSAGSSYLINDGKKTSKFLKKAGDVIKNLLVRLWIWLLVLVIFLCAITGENMTGFRICYMALFLFFLLVFQSSSKAWVKIMYGFWLFLIFYAMSILILIYTYQFDKFDTYWSDYLNVSATLQKDIGLKRYQTKDLFLHLVSPTIIVILTVIQVHYFHKRFIASLQQQPLAGGSAQQKPTETTALEPAPSKRRGSA----------------GSLRKSQGPSAEAAPGATTDFETSVRDLVRISFRKIKNKSEYIFKNFKDVFWRFLELHIMKAVYIAAFVCSVSEVCVLHIIFVGFCVLGATSRKAVQVVISRLISFIVTVIVLSKMIYQIEYLSHSQHNVVCSD-------------------NRTANNAEWIGLTKADKVTGGLMSLLRTYIIYMVIVTMHAVISLRQLQMRVKIGALNAPPTKLLFPNIIRADAEKDLVGLVKYLLNFGFYKFGIEISLIALVSTITYRQDIVAVVYALWLVVLLLLR-RSQCAKIWGVFQAFFAISILTQYIVLVGLPPSSCLVFPWDE---GPFGEGIQRWAMLPGALHFNHVPKLIFDFIVLVILNRQKSIFCIEQRYASNDDYPGGSNRSVIADIAQLGRVPFDNPTHDFCSYIRNYSDILKNGVLCGFYWFTLAVVFLAGTNIADLLALGYLIGAFIFLWQGSDFYLRPIHTIIFRWKWLLAFNVANILIKTSFQMAGCLFMTQLTKDCCWLVHMLGITCTSNVLTEQIMLPEEAELALKPGECP-KITHQVVLLWDTICFAFIIFQLRIFKSHYFCHIITDTKANNILASRGADIIESLRHKQIAHRHDHEKQVLHKIKRKMERIRATQQKMLRPLDKQTHFDEHGYPLPAPTVRRRKEIKLHPHATRAGDYYMFEEMDDKFELDLIHDEIDFLEEENITESEMKMQRRKTLYDKSKDAPTGEFPSTSKGISKERDAATASSSASPAPTRDVGDLPVIPPPSTGLGREQTSKETSDSKSKMEVDSGEVTAKDSDEDFDTNPIIRLLEGFLVT-LTIRLNRFSRNYRFVNRILAGEKKTLKESSSLNRLGLSSAAAMFHFLKSNLESDESEPPASSSTPRRVVIAPPNATEHSDPTSTTLNTNTTTTPLSPPEPLQPLQPLQPNTTSTPQQQHQHIRAAEEIIELPVDTVDGVAHRKQSINSSPPAKGAGEFNLEEEN-FAQRDHHIIVEVLISSWYALLANTDLICYIVVFINQVVNASLISLPLPIMVFLWGTLSLPRPTKTFWVTLIAYTQAIVLIKCIFQFKLIWSNYHQLP----NQPLTPAKIFGVENKAHYAIYDLILLLVLFLHRYLLKSQGLWKSGYKDTDNQFTKPTASID-------------------------------------ERDDSDNLSQPDSRQLNDDAAQKLSLQVSQASLPGSPEFSKTGINQLER---------------------------------TKYT--------------SSLYKFFFSLVHKS-RLATDVYALMFLCDFVNFFVLLFGFTAFGTQQTESDEGVQTYLAENKVPIPFLIMLLVQFLLIVIDRALYLRKALVNKIIFHFFSVIGIHIWMFFVVPAVTERTFNSLAPPIIFYVIKCFYMLLSSYQIKSGYPKRILGNFFTKGFSMVNMIAFKVYMQIPFLYELRTILDWVCIDSTMTIFDWLKMEDIFSNIYLIRCTRQSETDFPAMRAQKKASLSKLIMGGTIVLLIVICIWGPLCLFALGN-AVGTSNVPFHVSLSIRIGPYDPIYTTNNYD-SIFEINPEMYSQMTNAYIKEKQALTFIAGYDATDVAAVRLAGNSPSLWNIAPPDRQRLLNDLRN-NHTLKARFSYSLTRKAPAKGLKENVGDEHAISLDES-FEGRAALIHMLSETHDVEPIYSNGTTNGTTPEVEEVVVIPGMIPKFIKVLNSGDAAVVSVLSPKHYD--YRPLVIKMHRDNETNGLWWEIRDYCNDTFYNETLSKFAYSNCTSGIVMYTFNDKKFPSTFSFLTAGGIIGLYTTFVLLASRFMKSFIGGQNRKIMFEDLPYVDRVLQLCLDIYLVREALEFALEEDLFAKLLFLYRSPETLIKWTRPKEEYVDDDGDTDSIPSRMSVRRPEQLQPQQPQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A126GUQ2-1", "uniprot_id": "A0A126GUQ2_DROME", "id": "A0A126GUQ2-1", "name": "Piezo-type mechanosensitive ion channel component", "aln": "-MAEPLLFIITRIFLPLTLILVSLVRPVGLSYFYLLTFFLSPWLLQSNSLKQRTFLNVFIIFLCVLSTFGIVGHIIFNLINLFFVDLS----SKNSFSF-ILRQFGFLYFKGLSFVSIAHWILPDIIVLLNTIVFFIFSEIKYKR-------------EKRVIQNDDDVFYK---KSKELKGALKVAEIN----------------------RVLII---VYIRSVLKTSLIFSLIVLYFAATLRPSLPGSLYFCMFIIAGSYWALFR---QRKMYYSVIFMIVALLVHITCIFAYQLPVLQNTINCDKLWTRLMGMEVLIRLNKDNRNGKILELNPKLNLDSYLSPIALMLAYFATTLSLINRS------------------------QYEISFNTIRMN-----------LGPKSNSIYDNIQPSNEENEEISIFTEPSMLEQFFYI-VYELSSFVYKNSYILLNIIMMIWSIVYHSWLTFVLLIWANILWMIPNQRRSMMRSSLFVVFYSQILLLAQYIYGMNLYESELPTKVTSCGLNLEQIGFVHPQSKDSLPWIPLTVKTVFLFVFWVTSRQYFREISLDRQQSDLLQQIFATHRSR----SEHLLSKKSQTPQIFIYILKSTSHFITRIWMWLLIFLIFLCAMIDRTMTGIRICYMSLFLLFLMVFQMSLQLWIRFLYGYWIFLIFYAMTILTAIYTYQFDHFDYYWEKFLKVHSTLQCDIGLRRYQTKDLFLHLLIPTLTVIFTVVQLHYFHRRFVESVRRP---------RSTEGQNFHLAPN------------------------------AETRASQKTLDIHRQSWKVFFDAGYENVRAKGRQLFNPGKIVAWKFLEMHMIKTVTLASFYCAISEICFLNLFLVILSLLGICGNRFLRRVIFRAVTFWISLLVLMKMIYQIKYLDQSHYNFKCG--------------------NVTVNFAEWMGLRKTGTVFGVHLRYISSYIIYMILTSLHAVVKLRDHLIRYSTHKQKD--TKLLFPDITRQDAERDFPGLLKYVLNYGYFKFGFEITMIGLMSTIAHRRDLFALTYLIWLVLLLCLS-RFRCARIWEMLQLYFVLSIFVQYVYLLNFPPNLCNVISYN-----------SLWSIS-GSKNYTNRSNIMFDYIVLLLISRQRKSFRVEMRHINDLSYRGGVNTNVVHNIAKLGHVYFENPTHDFCTYVRNYADVLKTAIFFSFFWITLAIVFLGGVCSTDILSLGYIIFALIFLLQGSEIYLQNIHFIICRWNCLIAFNIFNIIVKVAIIVLEGTINLEHKSILSIVFNVMHQTAPCENIMDGKFFEINEISEKKYCYGPSDMIFKNTLVWHAIIFSFVVFQYRIFGSYYFCHVIMDTQANTILASRGAAIIENLHYKQIYDRRKNEQSVLERVKMKMERIRITNRRHQK-QATGLDFQPHKPPSSIIHVHYRAEEKSK-----------LKTLNNEFLTTIKQAERDTYFSRSLKP------RRRDLSLHPHAVRTGDYYMFNE--LDDDDDLDVYEEYDFLEKEDVR--------ARQMRQSLRSRASNYNRSKSFLN--DENSDTDTKKLETHPVIILTSELIVL-LTFRLNRLSKNFRFVHKMLSAEKKKLQNISIMNRLGLSNTAAMFKFLNKSLNN------------------------------------------------------------------------------------------------KVIKEAGSYYVSQDNDFTTLDHNDFVQMLIALWYALIANTETICYLVVFLNQAANSSVISLPMPFLVLCWGALTLPRPSKTFWVTLITYNLTMIFVKSIMHQRVLLDQQLVSR----SNSLS----FELIMKRGRAVYDLLLLVVLFWHQYMLKKQGIWTIQRTNSELLLLEKKRNHY-------------------------------------KRSFSKERPENIRKLLREEGGGEQVKAVRPNAIEFKREMDDILLPALENK-------------------------YVYQNIESEYYRKAMQGLANKGGLLSGFRKFFLALRHKS-RLSTDVYTLLFLCDFISFFILLFGFPKFVYRYKYSTSVLETYIQGNKVPFTFLLMLIVQFITIVTERAIYLRKALIYKIFFHFISVLGIHIWMFFLVPYITSHSFGETAP-VLFYLIKCLHMLLSAYQIRCGYPKRILGNVFTKGYSLANYIAFKIYMEIPFLYILRTMLDWVCIDTTLTVMEWIKMEDIFQSVFIVRCYRQMDTDFPVLRGEPKALYSKLLIGGTIILILIALIWSPLFLFALVG-TVGKPNIPQKADITVKINHYEPIYVSQSNS-DILQFSNSDFQKLTNHIILDNYASDSMMLYDAVDVTAIKFYENSISLWNMPPPDKERLLHDLSN-GETLDIHLTLTLKCNLTP----EAVIYETTYTLTENKVHTRDKLIRLMSNN------FSN-----------EKVIIPNILPKFITVQRQQANAKFIKDYDGKFN--RPIILTKIGK---SQVYWWEMNDYCNDRFYTEILSALPLSNCENGVVLYVFNDKSFPSAMSFLEKTGIIGLYTTFVYVVSRIIRSLIANNHRRIMFEDLPYVDRVLKLCTDIYLVRETQEYRLEEDLYGKLIFLYRSPETLIKWTRFKEDISETASN-----SQLSIQRN---------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .:* *: ..:.* .:* .*** ::: *:. .. : * * : ::.*: ::: . . . : ::.*. : . : *:: :: : . :: : : . : : * :*. ** ...*: :*: ::*: : : * .: ** . * : : :*::*:: :: . . * * .* *:: : : : .: : . . : . :. :: .:**: * ** *** **********: : ::* : .::: .* :::*. * :*::.*:* *** : :.*.*:*: :. * : * . : : **: ** .:: . . : :. :: . .: *::: :::: :: .. :. :* ** ***: : ::* * ::: :* ::: *:* :* :**:**:.* ** . . *:**. :. .:** :: * : :: ::*:****: *: : :. : :. : . .**:*:.* * : . :: * . :::.:* : :. .: : :. :::: **:**:. :. .:. * . ..: *.*:*: * * : :: ::: :.* : :: . : .. * ::.: :**.:*: ::***:** :: :..* * ::.. : *** :: * * :* ::.: :: **: :.:** * .: * . : ::: *:::*: .:* * * .: .* * . : * *.* *: * :: ::*:.* :**: *. .::.***:: .: :* *: : : : : *. *: :*: *: * : : : : . . :.::: ... : : . : ::*.:: * *:::* *:* *.*: *: * :*. **** : . *.: :: *. : ::* .*:*** .:.: : * . . * * . . : . : : . . . :. .: : * :* *. :::.. :* *: : . . : . . . : : :.:* : : : *::: :**:::.:*: ..:* ** :*.:*: *. *::***:* **:* * :. :. * ::: .: : .:. : : . ***: *:.** *: * *:* . . : . : .. : ** : * . * :****:*:** *.:.:.:::*** * : : : : : ::** .**.**::** :: :**:****::: :: *:. *..**:****::* :*.: * ::*..**::: **:***:.***.*****.:** :. * : *: : :*** **:::*** *:*::: .*: :***: .:::::* *: :..:* :.: * * :** *:*::: ** ** :::* .** * * .. :::::. *:*::. . . .* :. . :.::.. * : *. *:.: .: .* ::*.:.**.: .: .:* . : :: .: . * . : * . : . : * :* ::*::* . . . : . :. . : : *.** *.::.** **:***.:.* : .::::.::. : ****:** .**:*:** **:****: * ***:*:.**:********:***** :: ", "identical_positions": 387, "similar_positions": 678, "identity": "14.17%" }, { "cls_id": "homologset.agr.RGD:1308825", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "G3V6W6-1", "uniprot_id": "G3V6W6_RAT", "id": "G3V6W6-1", "name": "26S proteasome regulatory subunit 10B", "aln": "---------------------------------MALPGIPYERRLLIMAD-PRDKALQDYRKKLLEHKEIDGRLKELREQLKELTKQYEKSENDLKALQSVGQIVGEVLKQLTEEKFIVKATNGPRYVVGCRRQLDKSKLKPGTRVALDMTTLTIMRYLPREVDPLVYNMSHEDPGNVSYSEIGGLSEQIRELREVIELPLTNPELFQRVGIIPPKGCLLYGPPGTGKTLLARAVASQLDCNFLKVVSSSIVDKYIGESARLIREMFNYARDHQPCIIFMDEIDAIGGRRFSEGTSADREIQRTLMELLNQMDGFDTLHRVKMIMATNRPDTLDPALLRPGRLDRKIHIDLPNEQARLDILKIHAGPITKHGEIDYEAIVKLSDGFNGADLRNVCTEAGMFAIRADHDFVVQEDFMKAVRKVADSKKLESKLDYKPV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62333-1", "uniprot_id": "PRS10_HUMAN", "id": "P62333-1", "name": "26S proteasome regulatory subunit 10B", "aln": "-----------------------------------------------MAD-PRDKALQDYRKKLLEHKEIDGRLKELREQLKELTKQYEKSENDLKALQSVGQIVGEVLKQLTEEKFIVKATNGPRYVVGCRRQLDKSKLKPGTRVALDMTTLTIMRYLPREVDPLVYNMSHEDPGNVSYSEIGGLSEQIRELREVIELPLTNPELFQRVGIIPPKGCLLYGPPGTGKTLLARAVASQLDCNFLKVVSSSIVDKYIGESARLIREMFNYARDHQPCIIFMDEIDAIGGRRFSEGTSADREIQRTLMELLNQMDGFDTLHRVKMIMATNRPDTLDPALLRPGRLDRKIHIDLPNEQARLDILKIHAGPITKHGEIDYEAIVKLSDGFNGADLRNVCTEAGMFAIRADHDFVVQEDFMKAVRKVADSKKLESKLDYKPV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62334-1", "uniprot_id": "PRS10_MOUSE", "id": "P62334-1", "name": "26S proteasome regulatory subunit 10B", "aln": "-----------------------------------------------MAD-PRDKALQDYRKKLLEHKEIDGRLKELREQLKELTKQYEKSENDLKALQSVGQIVGEVLKQLTEEKFIVKATNGPRYVVGCRRQLDKSKLKPGTRVALDMTTLTIMRYLPREVDPLVYNMSHEDPGNVSYSEIGGLSEQIRELREVIELPLTNPELFQRVGIIPPKGCLLYGPPGTGKTLLARAVASQLDCNFLKVVSSSIVDKYIGESARLIREMFNYARDHQPCIIFMDEIDAIGGRRFSEGTSADREIQRTLMELLNQMDGFDTLHRVKMIMATNRPDTLDPALLRPGRLDRKIHIDLPNEQARLDILKIHAGPITKHGEIDYEAIVKLSDGFNGADLRNVCTEAGMFAIRADHDFVVQEDFMKAVRKVADSKKLESKLDYKPV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9W414-1", "uniprot_id": "Q9W414_DROME", "id": "Q9W414-1", "name": "", "aln": "---------------------------------MTVTATP-------MPDNLRVKALSEYRKKLLEHKEIEGRLKEKREEIKDLTKLYDKSENDLKALQSVGQIVGEVLKQLTEDKFIVKATNGPRYVVGCRRQLDKAKLKSGTRVALDMTTLTIMRYLPREVDPLVYNMSHEDPGDVTYSAIGGLTDQIRELREVIELPLLNPELFLRVGITPPKGCLLYGPPGTGKTLLARAVASQLDANFLKVVSSAIVDKYIGESARLIREMFNYARDHQPCIIFMDEIDAIGGRRFSEGTSADREIQRTLMELLNQMDGFDSLGQVKMIMATNRPDTLDPALLRPGRLDRKIEIPLPNEQARLEILKIHALKIAKHGEIDYEAIVKLSDNFNGADLRNVCTEAGLFAIRAEREYVIQEDFMKAVRKVSDNKKLESKLDYKPV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VTQ9-1", "uniprot_id": "Q9VTQ9_DROME", "id": "Q9VTQ9-1", "name": "", "aln": "---------------------------------MSAPLAN------PPTDDERVRALTNYRTKLLEHREIESKLKALRDKYKVVNAEYEKSEDDLKALQSVGQMVGEILKQLTPDNFIVKASNGPRYVVGCRRQINKEKLKPGTRVALDVTTLTIMRYLPREVDPLVYNMTHEDPGNVNYAEIGGLGQQIRELREVIELPLLNPDIFLRVGISPPKGCLLYGPPGTGKTLLARAIASQMDANFLKVVSSAIVDKYIGESARLIREMFAYARDHQPCIIFMDEIDAIGGRRFSEGTSADREIQRTLMELLNQMDGFDALGQVKMIMATNRPDTLDPALLRPGRLDRKLEIPLPNEVARMDILKIHAEPLNKRGEIDYEAVVKLSDLFNGADLRNICTEAGLFALRCDREFVIQEDFMKAVRKIADNKKLESRLDYKPI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53549-1", "uniprot_id": "PRS10_YEAST", "id": "P53549-1", "name": "26S proteasome subunit RPT4", "aln": "MSEEQDPLLAGLGETSGDNHTQQSHEQQPEQPQETEEHHEEEPSRVDPEQEAHNKALNQFKRKLLEHRRYDDQLKQRRQNIRDLEKLYDKTENDIKALQSIGQLIGEVMKELSEEKYIVKASSGPRYIVGVRNSVDRSKLKKGVRVTLDITTLTIMRILPRETDPLVYNMTSFEQGEITFDGIGGLTEQIRELREVIELPLKNPEIFQRVGIKPPKGVLLYGPPGTGKTLLAKAVAATIGANFIFSPASGIVDKYIGESARIIREMFAYAKEHEPCIIFMDEVDAIGGRRFSEGTSADREIQRTLMELLTQMDGFDNLGQTKIIMATNRPDTLDPALLRPGRLDRKVEIPLPNEAGRLEIFKIHTAKVKKTGEFDFEAAVKMSDGFNGADIRNCATEAGFFAIRDDRDHINPDDLMKAVRKVAEVKKLEGTIEYQKL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :** ::: *****:. :.:** *:: : : *:*:*:*:*****:**::**::*:*: :::****:.****:** *..::: *** *.**:**:******* ****.*******: : *::.: **** :************* **::* **** **** **************:*:*: :..**: :*.***********:***** **::*:********:**************************.****** * :.*:***********************:.* **** .*::*:***: : * **:*:** **:** *****:** .****:**:* :::.: :*:******::: ****. ::*: :", "identical_positions": 240, "similar_positions": 98, "identity": "54.92%" }, { "cls_id": "homologset.agr.RGD:1308828", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5RJM1-1", "uniprot_id": "SR5A3_RAT", "id": "Q5RJM1-1", "name": "Polyprenal reductase", "aln": "MAGWAGAELSVLN------PLRALWLLLAAAFLLALLLQLAPARLLPSCA-LFQDLIRYGKTKQSG--SRRPAVCRAFDVPKRYFSHFYVVSVLWNGSLLWFLSQSLFLGAPFPSWLWALLRTLGVTQFQALGMESKASRIQGKKLALSTFLVLVFLWVHSLRRLFECFYVSVFS-NTAIHVVQYCFGLVYYVLVGLTVLSQVPMNDKNVYALGKNLLLQARWFHILGMMMFFWSSAHQYKCHVILSNLR-RNKKGVVIHCQHRIPFGDWFEYVSSANYLAELMIYISMAVTFGLHNVTWWLVVTYVFFSQALSAFFNHRFYKSTFVSYPKHRKAFLPFLF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WUP4-1", "uniprot_id": "SR5A3_MOUSE", "id": "Q9WUP4-1", "name": "Polyprenal reductase", "aln": "MAGWAGFELSALN------PLRTLWLALAAAFLFALLLQLAPARLLPSCA-LFQDLLRYGKTKQSG--SRRPAVCRAFDVPKRYFSHFYVISVVWNGSLLWLLSQSLFLGAPFPNWLSALLRTLGATQFQALEMESKASRMPAAELALSAFLVLVFLWVHSLRRLFECFYVSVFS-NAAIHVVQYCFGLVYYVLVGLTVLSQVPMDDKNVYVLGKNLLIQARWFHILGMVMFFWSSAHQYKCHVILSNLR-RNKKGVVIHCQHRIPFGDWFEYVSSANYLAELMIYISMAVTFGLHNLTWWLVVTYVFSSQALSAFFNHKFYRSTFVSYPKHRKAFLPFLF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H8P0-1", "uniprot_id": "SR5A3_HUMAN", "id": "Q9H8P0-1", "name": "Polyprenal reductase", "aln": "MAPWAEAEHSALN------PLRAVWLTLTAAFLLTLLLQLLPPGLLPGCA-IFQDLIRYGKTKCGE--PSRPAACRAFDVPKRYFSHFYIISVLWNGFLLWCLTQSLFLGAPFPSWLHGLLRILGAAQFQ------------GGELALSAFLVLVFLWLHSLRRLFECLYVSVFS-NVMIHVVQYCFGLVYYVLVGLTVLSQVPMDGRNAYITGKNLLMQARWFHILGMMMFIWSSAHQYKCHVILGNLR-KNKAGVVIHCNHRIPFGDWFEYVSSPNYLAELMIYVSMAVTFGFHNLTWWLVVTNVFFNQALSAFLSHQFYKSKFVSYPKHRKAFLPFLF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5RIU9-1", "uniprot_id": "SR5A3_DANRE", "id": "Q5RIU9-1", "name": "Polyprenal reductase", "aln": "-------MFHILS------IVNIIWLLLALCFGAAFCLNKFSVKLPNRVEHVFQDFIRYGKTKEN---IKRASWQLVFDLSKRYFYHFYVVSVMWNGLLLLFSIRSVVMSEAFPDWIIDVLGSLTGRSRG-----------AWNEIHLSTLLLQVLLWVHTLRRLLECLFVSVFS-DGVINVVQYAFGLSYYIILGLTVLCTNDSLPQSESVS---FFNQLTWYHVVGTLLFFWASFLQHQSLSLLAKMR-TDSSGKVETLAHKMPCGGWFELVSCPHYLAELLIYAAMCVCCGCASLTWWMVVLYVLCNQALAAQLCHEYYRSKFKTYPHHRKAFIPFVL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P40526-1", "uniprot_id": "DFG10_YEAST", "id": "P40526-1", "name": "Polyprenal reductase", "aln": "----------MYF------DEEQLLKYTIYAYRLSFFVGICSLFIAKSCLPEFLQYGKTYRPKENSKYSSILERIKKFTVPKAYFSHFYYLATFLSLVTLYFYPK---------------------------------------------FPIVWIIFGHSLRRLYETLYVLHYTSNSRMNWSHYLVGIWFYSVLLLILNISLYKN------------SIPNTLNMNAFIIFCIASWDQYKNHVILANLV-KYS----------LPTGRLFRLVCCPHYLDEIIIYSTLLP----YEQEFYLTLVWVITSLTISALETKNYYRHKFKDNHVAPYAIIPFII", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VLP9-1", "uniprot_id": "SR5A3_DROME", "id": "Q9VLP9-1", "name": "Polyprenal reductase", "aln": "MAPPENGILEVLENLLDRYKINLLQMMFGTFIATIVFFGGLMTFVEKYLPNSIRQSFRYGKHSFKG---ETDPLVAWLEVPKSWFKHFYTFALFWSWLAFYVLVSTVREQKEAPEYVLQFLDIMGGGRSHR----------KVEIDSTTACVGAFMLTLQCTRRFYETNFVQIFSKKSKINLSHYAVGYVHYFGAVIALLSNTSGFVRGSKPMEFS-LDKLTSQQILYLGVFFLAWQQQYASNMILVNLRKDPRTGSVKTEKHLLPKGGLFNLLSSPHMFLEVVMYFCIADLY-MPVRIWRLIFLWVASNQTINALLTHKWYQETFREYPKNRRAIIPFLL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . . : : : : : . : :.* :* *** .: . . : :: : **: * :* :: . :: :* .* .* : : :: :* : *: :* :: :* * *. :...: : *:::* : : : . * . :: * :.:*: .* *::**::", "identical_positions": 27, "similar_positions": 69, "identity": "7.92%" }, { "cls_id": "homologset.agr.RGD:1308829", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZN89-1", "uniprot_id": "A0A8I5ZN89_RAT", "id": "A0A8I5ZN89-1", "name": "Glutaryl-CoA dehydrogenase, mitochondrial", "aln": "MVPAMLTGYMSLRGVSAWLLSRKLGLRFSRVPRTWSSAAAHTEK---TQIRSVKSSRPVFDWKDPLVLEEQLTADEKLIRDTFRNYCQERLMSRILLANRNEVFHRDIVYEMGELGVLGPTIKGYGCAGVSSVAYGLLTRELERVDSGYRSMMSVQSSLVMHPIYTYGSEEQRQKYLPRLAKGELLGCFGLTEPNHGSDPGSMETRARHNPSNKSYTLSGTKTWITNSPVADLFVVWARCEDNCIRGFLLEKGMRG--LSAPRIEGKFSLRASATGMIIMDSVEVPEENVLPNVSSLAGPFGCLNTARYGITWGVLGAAEFCLHTARQYALDRIQFGVPLARNQLVQKKLADMLTEITLGLHACLQLGRLKDQDKATPEMVSLLKRNNCGKALDIARQARDILGGNGISDEYHVIRHAMNLEAVNTYEGTHDIHALILGRAITGIQAFTVEK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60759-1", "uniprot_id": "GCDH_MOUSE", "id": "Q60759-1", "name": "Glutaryl-CoA dehydrogenase, mitochondrial", "aln": "---------MSLRGVSARLLSRRSGLRFPRFPRTWSSAAAHTEK---TQIRPAKSSRPVFDWKDPLILEEQLTADEKLIRDTFRNYCQERLMSRILLANRNEVFHRDIVYEMGELGVLGPTIKGYGCAGVSSVAYGLLTRELERVDSGYRSMMSVQSSLVMHPIYTYGSEEQRQKYLPGLAKGELLGCFGLTEPNHGSDPGGMETRARHNPSNQSYTLSGTKTWITNSPVADLFIVWARCEDNCIRGFILEKGMRG--LSAPRIEGKFSLRASATGMIIMDSVEVPEENVLPNVSSLAGPFGCLNTARYGITWGVLGAAEFCLHTARQYALDRIQFGVPLARNQLVQKKLADMLTEITLGLHACLQLGRLKDQDKATPEMVSMLKRNNCGKALDIARQARDILGGNGISDEYHVIRHAMNLEAVNTYEGTHDIHALILGRAITGIQAFTVGK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92947-1", "uniprot_id": "GCDH_HUMAN", "id": "Q92947-1", "name": "Glutaryl-CoA dehydrogenase, mitochondrial", "aln": "---------MALRGVSVRLLSRGPGL---HVLRTWVSSAAQTEKGGRTQSQLAKSSRPEFDWQDPLVLEEQLTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLGPTIKGYGCAGVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCEDGCIRGFLLEKGMRG--LSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGASSLGGPFGCLNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHACLQLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEAVNTYEGTHDIHALILGRAITGIQAFTASK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VMC6-1", "uniprot_id": "Q9VMC6_DROME", "id": "Q9VMC6-1", "name": "glutaryl-CoA dehydrogenase (ETF)", "aln": "---------MIAQSVISKLRP---------CARRLASTSS-------------KAAAPKFNWQDPLNLESQLTEEEVAIRDAFRGYCQAELQPRVKMANRLETFDKKIMEEIGSLGVLGCTIKGYGCAGVSSVAYGLLTREVERVDSAYRSAVSVQSSLAMGAIYDFGSEEQKQRYLPSMAEGKLIGAFGLTEPNHGSDPAGMETRAKYDSKSKTYILNGSKTWITSAPIADVIVVWAKCEDGKVRGFLVDRKISGKGLETPKIEGKFSLRASPTGMILMDEVRVPEEQLLPNVAGFSGPFSCLNNARYGIAWGALGAAETCVEIARQYTLDRKQFGRPLAANQLIQKKLADAITEIALGLQACLHVGRLKDQKLHTPDMISLLKRNNTGKSLDIARQMRDMLGANGISDEYHVIRHVINLESVNTYEGTHDIHALILGRAITGLAAFAN--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :.* * . * *::: *:: * *:*:*** **.*** :* ***:** *** .* .*: :*** *.*.:.*: *:*.***** ******************:**:*****.*** :******.* .** :*****:*:*** :*:*:*:*.******* ****..*****:::...::* *.*:*****.:*:**:::***:***. :***:::: : * *.:*:*:********.****:** *.****::**..:.:.***.***.*****:**.***:* *:. ****:*** *** *** ***:****** :***:***:***::******. :*:*:*:***** **:****** **:**.************.:***:*********************: **: ", "identical_positions": 265, "similar_positions": 106, "identity": "58.63%" }, { "cls_id": "homologset.agr.RGD:1308830", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "F1LYH3-1", "uniprot_id": "F1LYH3_RAT", "id": "F1LYH3-1", "name": "5-taurinomethyluridine-[tRNA] synthase subunit MTO1, mitochondrial", "aln": "-----------------MFLLRDCGRWASASLG-RRLPLRRL---------RSDSAAPCSPHFDVVVIGGGHAGTEAAAAAARCGSRTLLLTHRVDTIGQMSCNPSFGGIGKGHLMREVDALDGLCSRVCDQSGIHYKVLNRRKGPAVWGLRAQIDRKLYKQNMQKEILS---TPLLTVQEGAVEDLVLAEPEPGYGGKSRVRGVVLADG-STMHAESVVLTTGTFLRGALIIGLEVHPAGRLGDQPSIG-LAQTLE-KLGFMVGRLKTGTPPRLAKESINFSILHEHTADNPPIPFSFLSDDVWIKPEDQLPCYLTHTNPRVDELVLENLHLNSHVKET-TRGPRYCPSIESKVLRFPNRL-HQVWLEPEGMDSDLIYPQGLSVTLPAELQEKMITCIRGLEKAKMVHP-------------------------GYGVQYDYLDPRQISPSLETHLVQRLFFAGQINGTTGYEEAAAQGVIAGINAS--LRVSRKPPFVVSRTEGYIGVLIDDLTTLGTSEPYRMFTSRVEFRLSLRPDNADTRLTFRAHEDAGCVSPQRYKRALWMKSSLEEGISVLKSIKFSSSKWKKLIPQAPISINRSLPVSALDVLKY--EEVDMESLASVVP-EPLKKYTACRELARRLKIEATYESVLLYQLQEIKEVQQDEALQLPQDLDYLTIKDVSLSQEVREKLHLSRPQTIGAASRIPGVTPAAIINLLRFVRNTQQRQTAVMEH-QTNQCL-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q923Z3-1", "uniprot_id": "MTO1_MOUSE", "id": "Q923Z3-1", "name": "5-taurinomethyluridine-[tRNA] synthase subunit MTO1, mitochondrial", "aln": "-----------------MFLLRGRGHWAAASLG-RRLPLRRL---------RSDSAAPCTPHFDVVVIGGGHAGTEAAAAAARCGSRTLLLTHRVDTIGQMSCNPSFGGIGKGHLMREVDALDGLCSRICDQSGIHYKVLNRRKGPAVWGLRAQIDRKLYKQNMQKEILS---TPLLTVQKGAVEDLVLAEPEPGYPGKSRVRGVVLADG-STIYAESVILTTGTFLRGMIIIGLEMHPAGRLGDQPSIG-LAQTLE-KLGFMVGRLKTGTPPRLGKESINFSILNKHTPDDPSIPFSFLSDSVWIKPEDQLPCYLTHTNPRVDAIVLENLHLNSHVQET-TKGPRYCPSIESKVLRFPNRL-HQVWLEPEGMDSDLIYPQGLSVTLPAELQEKMITCIRGLEKAKMVHP-------------------------GYGVQYDYLDPRQISPSLETHLVQRLFFAGQINGTTGYEEAAAQGVIAGINAS--LRVSRKPPFVVSRTEGYIGVLIDDLTTLGTSEPYRMFTSRVEFRLSLRPDNADTRLTFRAHKEAGCVSSQRFERALWMKSSLEEGISVLKSIKFSSSKWKKLIPQIPISINRSLPVSALDVLKY--EEVDMESLVGVLP-EPLEKYTACRELARRLKIEASYESVLSYQLQEIKEVQQDEALQLPHELDYLTIRDVSLSQEVREKLHLSRPQTIGAASRIPGVTPAAIINLLRFVRSTRQSRQQ----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y2Z2-1", "uniprot_id": "MTO1_HUMAN", "id": "Q9Y2Z2-1", "name": "5-taurinomethyluridine-[tRNA] synthase subunit MTO1, mitochondrial", "aln": "-----------------MFYFRGCGRWVAVSFTKQQFPLARL---------SSDSAAPRTPHFDVIVIGGGHAGTEAATAAARCGSRTLLLTHRVDTIGQMSCNPSFGGIGKGHLMREVDALDGLCSRICDQSGVHYKVLNRRKGPAVWGLRAQIDRKLYKQNMQKEILN---TPLLTVQEGAVEDLILTEPEPEHTGKCRVSGVVLVDG-STVYAESVILTTGTFLRGMIVIGLETHPAGRLGDQPSIG-LAQTLE-KLGFVVGRLKTGTPPRIAKESINFSILNKHIPDNPSIPFSFTNETVWIKPEDQLPCYLTHTNPRVDEIVLKNLHLNSHVKET-TRGPRYCPSIESKVLRFPNRL-HQVWLEPEGMDSDLIYPQGLSMTLPAELQEKMITCIRGLEKAKVIQPDGVLLLLPRMECNGAISAHHNLPLPGYGVQYDYLDPRQITPSLETHLVQRLFFAGQINGTTGYEEAAAQGVIAGINAS--LRVSRKPPFVVSRTEGYIGVLIDDLTTLGTSEPYRMFTSRVEFRLSLRPDNADSRLTLRGYKDAGCVSQQRYERACWMKSSLEEGISVLKSIEFLSSKWKKLIPEASISTSRSLPVRALDVLKY--EEVDMDSLAKAVP-EPLKKYTKCRELAERLKIEATYESVLFHQLQEIKGVQQDEALQLPKDLDYLTIRDVSLSHEVREKLHFSRPQTIGAASRIPGVTPAAIINLLRFVKTTQRRQSAMNESSKTDQYLCDADRLQEREL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W245-1", "uniprot_id": "Q9W245_DROME", "id": "Q9W245-1", "name": "tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain domain-containing protein", "aln": "-----------------MQQLRN----AVVHGWARRIRAPSR---------SAHSAG--ADIYDVVVIGGGHAGTEASAAAARMGSRTLLLTHKLETIGEMSCNPSFGGIGKGHLMREVDALDGVCARCCDVSGVHYKVLNRRRGPAVWGPRAQIDRQLYKKAVQQELHS---TPNLEIRAAAVDNLLIEDEQD--TQARRCTGVLLANG-EVVRSRSVVLTTGTFLRAHINIGLEVRPAGRIGDAPAKA-LGEAID-RLGFRMGRLKTGTPPRIAKDSVDFSQLQRHEGDDPPMPFSFLNKDVWLPAKDQLPCYLTYTTPKVSDIVRDNLHVNRHVTEE-ITGPRYCPSIESKILRFGAKV-HQVWLEPEGLDSSLVYPQGISCTLPHDQQVELVHAIQGLEKAVVVQP-------------------------GYGVEYDFIDPRELYPTLETKRVPGLFFAGQINGTTGYEEAAAQGIIAGANAAGKTRHSDGRQLTISRTEGYIGVLIDDLTSLGTNEPYRMFTSRAEFRLSLRPDNADMRLTQKGY-EFGLVSSDRYQHFQQTEARLQSAIESLRRLRKHTHYWRQALNLP--KAKASVEKSAFDMLGIPADNITIEQLIHLHP-NELSWLKGERNLAERLKIEALYSFFVDEQQRDVEDVRREERLSIPADIDYFS-KSLSLSNEERQKLTLIQPQTIAAASRIQGVTPSTIVRILKYVKKAELAKA-----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M3B787-1", "uniprot_id": "A0A8M3B787_DANRE", "id": "A0A8M3B787-1", "name": "", "aln": "MTAVKPAETQSSQHDIYIEISKNSVTLQVSVPQLSHMLVRRLQFLKTLSTCSIEASNIHTQHYDVIVVGGGHAGSEAVAAASRIGAKTLLITQKIQTIGALSCNPSLGGVGKGHLVREIDALDGVMGRAGDWAGIHFSILNRSKGPAVWGLRAQLDRQRYKDFMQSELLS---TPLVTILEGSVQDLLLTEADPGKPGKHKVYGICLANGGGEIHSSSVVLTTGTFLSGALFMGQNTTPGGRMGDPPSCAGLSHNLKNVLGLKIGRLRTGTPPRIVKDSIDFSLTSVCLPDSSPTPFSFINKHTHCTPKEQLPCFLTYTTPGVEKVVKESSHLNSHIQQD-IKGPRYCPSIESKVLRFPGRQ-HQVWLEPEGLTSSLMYPQGLSMTMPLEMQLRLIREIPGLQHAKIQTP-------------------------GYGVQYDFVCPTQLFPWLQLKNTQGLFLAGQINGTTGYEEAAAQGLWAGVNAG--RTSLSMSPLSLSRTQSYIGVLIDDLVCHGVTEPYRMFTSRAEFRTSLRPDNADLRLTIRGFEEIGCVSEQRYNKALLVQASLKQALSTLQSIHLSAARWRDKLGGVTISKTKSSILNGVEVLQY--KDVTFQMLASSFQ-ELFG---PHLEISERLKVEALYHPHCEKQRREMEKMQTEESLSLPNDIDYLA-LPISLSQEVREILDRVRPSTLGAAARLPGITPAAIVHLFNYVHRNKHRNHM----------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P53070-1", "uniprot_id": "MTO1_YEAST", "id": "P53070-1", "name": "Mitochondrial translation optimization protein 1", "aln": "-------------------MLRVTTLASSCTSFPLQVLRRRLT-------ISSLTSFQPTTKTQVVVIGAGHAGCEAAAASSRTGAHTTLITPSLTDIGKCSCNPSIGGVGKGILVKEIDALDGLMGKVTDLAGVQFKMLNRSKGPAVWGPRAQIDRELYKKYMQRELSDKKAHPNLSLLQNKVADLILYDPGCG---HKVIKGVVLDDG-TQVGADQVIITTGTFLSAEIHIGDKRIAAGRIGEQPTYG-ISNTLQNEVGFQLGRLKTGTPARLAKESIDFSALEVQKGDALPVPMSFLNETVSVEPTKQLDCFGTHTTPQMHDFLRNNLHQSIHIQDTTIKGPRYCPSIEAKILRFPDRSSHKIWLEPEGFNSDVIYPNGISNSMPEDVQLQMMRLIPGMANVEILQP-------------------------AYGVEYDYVDPRQLKPSLETKLVDGLFLAGQINGTTGYEEAAAQGIIAGINAG-LLSRQEREQLVLKRSEAYIGVLIDDLINNGVIEPYRMFTSRSEFRISVRADNADFRLTPIGA-QLGIISPVRLSQYSRDKHLYDETIRALQNFKLSSQKWSSLLQAN--IAPQAENRSAWEIFRF--KDMDLHKLYECIPDLPINLLDIPMHVVTKINIQGKYEPYIVKQNQFVKAFQADENMLLPQDYDYRQ--LPTLSTECKLLLNRVQPLTIGQARRIQGITAAALFELYRVARKPSQPVM-----------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :. :: : :*:*:*.**** ** :*::* *::* *:* : ** *****:**:*** *::*:*****: .: * :*:::.:*** :****** ***:**: **. :* *: . * : : * :*:: : *: * :* : : .*::****** . : :* : ..**:*: *: . :.. :. :*: :***:****.*: *:*::** * . *:** .. . . .** *: *:*.* : .: .. * . *: : *********:*:*** : *::******: *.::**:*:* ::* : * .:: * *: :. : * .***:**:: * :: * *: : . **:*****************: ** **. : :.*::.********* *. ********* *** *:*.**** *** . : * :* * .: : .. : *: :. : * . : : . ::: .:: :. * : .: :::::. * * : :: .: :* : :* : ** :** * : * :* *:. * *: *:*.:::..: . .: ", "identical_positions": 212, "similar_positions": 195, "identity": "28.04%" }, { "cls_id": "homologset.agr.RGD:1308831", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "F7FJV3-1", "uniprot_id": "F7FJV3_RAT", "id": "F7FJV3-1", "name": "", "aln": "------MDPGGQDLLALDPGDQDLLALDPGD-QDLLGFLLEESGDLWAATEQDIETPLDLELS-------PSENSVQELSDWEVEDLLSSLLSPSS-----------------SPDVLNSSS-SSILHDHNYSLPQEHVSIDL-------------------------DPGSFEKEGFRMNPLRVEETAAEQELSTLILTEEEKRLLEKEGLTLPSTLPLTKVEEQVLKRVRRKIRNKRAAQESRKKKKVYVVGLESRVLKYTAQNQELQNKVQHLEEQNLSLLDQLRKLQAMVTEIANKTSSGSTCVLVLLLSFCLLLVPAM--YSSDVRGSVPAEYVVLHRKLRALPSEDQHQPKLSALQPELPMGSTNQ-LESSEHTFLAPSNVSCLN-HMAQT---EQPPHW---------PLLDLSSEMPFSGSD-------LLLQANLTESGGWLSTHSPSSIILQGRYSG-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61817-1", "uniprot_id": "CREB3_MOUSE", "id": "Q61817-1", "name": "Cyclic AMP-responsive element-binding protein 3", "aln": "------MDPGGQDLLALDPGDQ-----------DLLGFLLEESGDLWAATEPDVKASLDLELS-------PSENSVQELSDWEVEDLLSSLLSPSV-----------------SRDVLGSSS-SSILHDHNYSLPQEHVSIDLGECEMISCRGRRELTGLAGSTFPFADTESFEKEGFHVTPLPGEERAAEQEMSRLILTEEEKKLLEKEGLTLPSTLPLTKVEEQVLKRVRRKIRNKRAAQESRKKKKVYVVGLESRVLKYTAQNRELQNKVQRLEEQNLSLLDQLRKLQAMVIEIANKTSSGSTCVLVLVFSFCLLLVPAM--YSSDARGSVPAEYVVLHRKLRALPSEDDHQPKPSALSSELPMDSTHQSLDSSEHMFLVSSNFSCVLYHAPQA---EQPLHW---------PLWDLSSEMLFSDSN-------LLLQANLSESEGWQPNHSPSLVIFQGRYSG-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43889-2", "uniprot_id": "CREB3_HUMAN", "id": "O43889-2", "name": "Cyclic AMP-responsive element-binding protein 3", "aln": "------ME------LELDAGDQ-----------DLLAFLLEESGDLGTAPDEAVRAPLDWALP-------LSEVP----SDWEVDDLLCSLLSPPA-----------------SLNILSSSNPCLVHHDHTYSLPRETVSMDL-------------------------ESESCRKEGTQMTPQHMEE-LAEQEIARLVLTDEEKSLLEKEGLILPETLPLTKTEEQILKRVRRKIRNKRSAQESRRKKKVYVGGLESRVLKYTAQNMELQNKVQLLEEQNLSLLDQLRKLQAMVIEISNKTSSSSTCILVLLVSFCLLLVPAM--YSSDTRGSLPAEHGVLSRQLRALPSEDPYQLELPALQSEVPKDSTHQWLDGSDCVLQAPGNTSCLLHYMPQAPSAEPPLEW---------PFPDLFSEPLCRGPI-------LPLQANLTRKGGWLPTGSPS-VILQDRYSG-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BEK7-1", "uniprot_id": "A0A8M2BEK7_DANRE", "id": "A0A8M2BEK7-1", "name": "", "aln": "MSVSEEMENADLLGLIFPDGEPGSGDLFLKEGNNFLDDFFSEQDMLSGMDTEDFLSSLLGEEDDGVMVNCMSQSPHGSDSGISEDTTPPHCQSPHDGSETDTVPSPGQEPLLYSECVTESYEAQVVQTDHCYTLPQDTNTLLSVRSENPESDVFIDVDDLDASMEDDDFSPELPCSLTIEDSMQSSKLDSQFQFKEIVLTDEEKRLLAKEGATIPSHMPLTKAEERTLKRVRRKIRNKQSAQESRKKKKVYVDGLENRVAVCTAHNQELQKKVEMLHKQNMSLIEQLRKLQAMVKMSTMKTTTTSTCIMVFLLSFCLIIFPSVNPFGSSDQKDLYASSTGMSRALRSYPAIKKDNIISTSAKEVVDQDVLLVATIENNQALLSAGQNHTPDYQRLEQSDSESGVNSNSSSDFPAPPQSDLKADATLSESHRNSGAPPVIYDGQSKSKESWMEQKPTSVIIQQHRSDEM", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: * : *: ::* ::.*.. * . :.* *: . *. . : ** * : * . : ** *:**:: :: . . . . .: :: :: ::**:*** ** *** :*. :****.**: ***********::*****:****** ***.** **:* ***:**: *.:**:**::********* : **:: ***::*::.****::.*:: :.*. : .: *. : * **: *: . : .: . : . .: : ..: : * . * ** :: . : :.: . . .* ..* :* * * . ", "identical_positions": 110, "similar_positions": 108, "identity": "23.5%" }, { "cls_id": "homologset.agr.RGD:1308832", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZQQ5-1", "uniprot_id": "A0A8I5ZQQ5_RAT", "id": "A0A8I5ZQQ5-1", "name": "", "aln": "------------------MSSTAEPPPPPPPESAPSKPSAAGA-GGSSSGNKGGPEGGAAPAAPSATGAGPADTEMEEVFDDGSPGKQKEIQEPDPTYE-EKMQTDRANRFEYLLKQTELFAHFIQPAAQKTP-TSPLKMKPGRPRVKKDEKQNLLSVGDYRHRRTEQEEDEELLTESSKATNVCTRFE----DSPSYVKWGKLRDYQVRGLNWLISLYENGINGILADEMGLGKTLQTISLLGYMKHYRNIPGPHMVLVPKSTLHNWMSEFKRWVPTLRSVCLIGDKEQRAAFVRDVLLPGEWDVCVTSYEMLIKEKSVFKKFNWRYLVIDEAHRIKNEKSKLSEIVREFKTTNRLLLTGTPLQNNLHELWSLLNFLLPDVFNSADDFDSWFDTNNCLGDQ-KLVERLHMVLRPFLLRRIKADVEKSLPPKKEVKIYVGLSKMQREWYTRILMKDIDILNSAG--KMDKMRLLNILMQLRKCCNHPYLFDGAEPGPPYTTDMHLVTNSGKMVVLDKLLPKLKEQGSRVLIFSQMTRVLDILEDYCMWRNYEYCRLDGQTPHDERQDSINAYNEPNSTKFVFMLSTRAGGLGINLATADVVILYDSDWNPQVDLQAMDRAHRIGQTKTVRVFRFITDNTVEERIVERAEMKLRLDSIVIQQGR--LVDQNLNKIGKDEMLQMIRHGATHVFASKESEIT-------------DEDIDGILERGAKKTAEMNEKLSKMGESSLRNFTMDT-----ESSVYNFEGEDYREKQKI-AFTEWIE-PPKRERK---ANYAVDAYFREALR------VSEPKAPKAPRPPKQPNVQDFQFFPPRLFELLEKEILYYRKTIGYKVP--------RSPDLP---------NAAQAQ------------KEEQLKIDEAGPLNDEELEEKEKLLTQGFTNWNKRDFNQFIKANEKWGRDDIENIAREVEG-KTPEEVIEYSAVFWERCNELQDIEKIMAQIERGEARIQRRISIKKALDTKIGRYKAPFHQLRISYG--TNKGKNYTEEEDRFLICMLHKLGFDKENVYDELRQCIRNSPQFRFDWFLKSRTAMELQRRCNTLITLIEREN---MELEEKEKAEKKKRGPK---------------------PSTQKRKMDGAPDGRGRKKKLKL--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91ZW3-1", "uniprot_id": "SMCA5_MOUSE", "id": "Q91ZW3-1", "name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5", "aln": "------------------MSSAVEPPPPPPPESAPSKPSAAGA-GGSSSGNKGGPEGGAAPAAPCAAGSGPADTEMEEVFDHGSPGKQKEIQEPDPTYE-EKMQTDRANRFEYLLKQTELFAHFIQPAAQKTP-TSPLKMKPGRPRVKKDEKQNLLSVGDYRHRRTEQEEDEELLTESSKATNVCTRFE----DSPSYVKWGKLRDYQVRGLNWLISLYENGINGILADEMGLGKTLQTISLLGYMKHYRNIPGPHMVLVPKSTLHNWMSEFKKWVPTLRSVCLIGDKEQRAAFVRDVLLPGEWDVCVTSYEMLIKEKSVFKKFNWRYLVIDEAHRIKNEKSKLSEIVREFKTTNRLLLTGTPLQNNLHELWSLLNFLLPDVFNSADDFDSWFDTNNCLGDQ-KLVERLHMVLRPFLLRRIKADVEKSLPPKKEVKIYVGLSKMQREWYTRILMKDIDILNSAG--KMDKMRLLNILMQLRKCCNHPYLFDGAEPGPPYTTDMHLVTNSGKMVVLDKLLPKLKEQGSRVLIFSQMTRVLDILEDYCMWRNYEYCRLDGQTPHDERQDSINAYNEPNSTKFVFMLSTRAGGLGINLATADVVILYDSDWNPQVDLQAMDRAHRIGQTKTVRVFRFITDNTVEERIVERAEMKLRLDSIVIQQGR--LVDQNLNKIGKDEMLQMIRHGATHVFASKESEIT-------------DEDIDGILERGAKKTAEMNEKLSKMGESSLRNFTMDT-----ESSVYNFEGEDYREKQKI-AFTEWIE-PPKRERK---ANYAVDAYFREALR------VSEPKAPKAPRPPKQPNVQDFQFFPPRLFELLEKEILYYRKTIGYKVP--------RSPDLP---------NAAQAQ------------KEEQLKIDEAEPLNDEELEEKEKLLTQGFTNWNKRDFNQFIKANEKWGRDDIENIAREVEG-KTPEEVIEYSAVFWERCNELQDIEKIMAQIERGEARIQRRISIKKALDTKIGRYKAPFHQLRISYG--TNKGKNYTEEEDRFLICMLHKLGFDKENVYDELRQCIRNSPQFRFDWFLKSRTAMELQRRCNTLITLIEREN---MELEEKEKAEKKKRGPK---------------------PSTQKRKMDGAPDGRGRKKKLKL--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60264-1", "uniprot_id": "SMCA5_HUMAN", "id": "O60264-1", "name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5", "aln": "------------------MSSAAEPPPPPPPESAPSKPAASIASGGSNSSNKGGPEGVAAQAVASAASAGPADAEMEEIFDDASPGKQKEIQEPDPTYE-EKMQTDRANRFEYLLKQTELFAHFIQPAAQKTP-TSPLKMKPGRPRIKKDEKQNLLSVGDYRHRRTEQEEDEELLTESSKATNVCTRFE----DSPSYVKWGKLRDYQVRGLNWLISLYENGINGILADEMGLGKTLQTISLLGYMKHYRNIPGPHMVLVPKSTLHNWMSEFKRWVPTLRSVCLIGDKEQRAAFVRDVLLPGEWDVCVTSYEMLIKEKSVFKKFNWRYLVIDEAHRIKNEKSKLSEIVREFKTTNRLLLTGTPLQNNLHELWSLLNFLLPDVFNSADDFDSWFDTNNCLGDQ-KLVERLHMVLRPFLLRRIKADVEKSLPPKKEVKIYVGLSKMQREWYTRILMKDIDILNSAG--KMDKMRLLNILMQLRKCCNHPYLFDGAEPGPPYTTDMHLVTNSGKMVVLDKLLPKLKEQGSRVLIFSQMTRVLDILEDYCMWRNYEYCRLDGQTPHDERQDSINAYNEPNSTKFVFMLSTRAGGLGINLATADVVILYDSDWNPQVDLQAMDRAHRIGQTKTVRVFRFITDNTVEERIVERAEMKLRLDSIVIQQGR--LVDQNLNKIGKDEMLQMIRHGATHVFASKESEIT-------------DEDIDGILERGAKKTAEMNEKLSKMGESSLRNFTMDT-----ESSVYNFEGEDYREKQKI-AFTEWIE-PPKRERK---ANYAVDAYFREALR------VSEPKAPKAPRPPKQPNVQDFQFFPPRLFELLEKEILFYRKTIGYKVP--------RNPELP---------NAAQAQ------------KEEQLKIDEAESLNDEELEEKEKLLTQGFTNWNKRDFNQFIKANEKWGRDDIENIAREVEG-KTPEEVIEYSAVFWERCNELQDIEKIMAQIERGEARIQRRISIKKALDTKIGRYKAPFHQLRISYG--TNKGKNYTEEEDRFLICMLHKLGFDKENVYDELRQCIRNSPQFRFDWFLKSRTAMELQRRCNTLITLIEREN---MELEEKEKAEKKKRGPK---------------------PSTQKRKMDGAPDGRGRKKKLKL--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24368-1", "uniprot_id": "ISWI_DROME", "id": "Q24368-1", "name": "Chromatin-remodeling complex ATPase chain Iswi", "aln": "------------------MSKTDTAAVEATEENSNETTSDAAT---SSSGEK------------------------EAEFDN-------------------KIEADRSRRFDFLLKQTEIFTHFMT-NSAKSP-TKPK----GRPKKIKD-KDKEKDVADHRHRKTEQEEDEELLAEDS-ATKEIFRFD----ASPAYIKSGEMRDYQIRGLNWMISLYENGINGILADEMGLGKTLQTISLLGYLKHFKNQAGPHIVIVPKSTLQNWVNEFKKWCPSLRAVCLIGDQDTRNTFIRDVLMPGEWDVCVTSYEMCIREKSVFKKFNWRYLVIDEAHRIKNEKSKLSEILREFKTANRLLITGTPLQNNLHELWALLNFLLPDVFNSSEDFDEWFNTNTCLGDD-ALITRLHAVLKPFLLRRLKAEVEKRLKPKKEMKIFVGLSKMQRDWYTKVLLKDIDVVNGAG--KVEKMRLQNILMQLRKCTNHPYLFDGAEPGPPYTTDTHLVYNSGKMAILDKLLPKLQEQGSRVLIFSQMTRMLDILEDYCHWRNYNYCRLDGQTPHEDRNRQIQEFNMDNSAKFLFMLSTRAGGLGINLATADVVIIYDSDWNPQMDLQAMDRAHRIGQKKQVRVFRLITESTVEEKIVERAEVKLRLDKMVIQGGR--LVDNRSNQLNKDEMLNIIRFGANQVFSSKETDIT-------------DEDIDVILERGEAKTAEQKAALDSLGESSLRTFTMDTNGEAGTSSVYQFEGEDWREKQKLNALGNWIE-PPKRERK---ANYAVDAYFREALR------VSEPKAPKAPRPPKQPIVQDFQFFPPRLFELLDQEIYYFRKTVGYKVP--------KNTELGS--------DATKVQ------------REEQRKIDEAEPLTEEEIQEKENLLSQGFTAWTKRDFNQFIKANEKYGRDDIDNIAKDVEG-KTPEEVIEYNAVFWERCTELQDIERIMGQIERGEGKIQRRLSIKKALDQKMSRYRAPFHQLRLQYG--NNKGKNYTEIEDRFLVCMLHKLGFDKENVYEELRAAIRASPQFRFDWFIKSRTALELQRRCNTLITLIEREN---IELEEKERAEKKKKAPKGSVSAGSGSASSNTPAPAPQPKASQKRKSEVVATSSNSKKKKK---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08773-1", "uniprot_id": "ISW2_YEAST", "id": "Q08773-1", "name": "ISWI chromatin-remodeling complex ATPase ISW2", "aln": "------------------MTTQQEEQRSDTKNSKSESPSEVLVDTLDSKSNGSSDDDNIGQSE--ELSDKEIYTVEDRPPEYWAQRKKKFVLDVDPKYAKQKDKSDTYKRFKYLLGVTDLFRHFIGIKAKHDKNIQKLLKQLDSDANKLSKSHSTVSSSSRHHRKTEKEEDAELMADEEEEIVDTYQEDIFVSESPSFVKSGKLRDYQVQGLNWLISLHENKLSGILADEMGLGKTLQTISFLGYLRYVKQIEGPFLIIVPKSTLDNWRREFLKWTPNVNVLVLHGDKDTRADIVRNIILEARFDVLITSYEMVIREKNALKRLAWQYIVIDEAHRIKNEQSALSQIIRLFYSKNRLLITGTPLQNNLHELWALLNFLLPDIFGDSELFDEWFEQNNSEQDQEIVIQQLHSVLNPFLLRRVKADVEKSLLPKIETNVYVGMTDMQIQWYKSLLEKDIDAVNGAVGKREGKTRLLNIVMQLRKCCNHPYLFEGAEPGPPYTTDEHLIFNSGKMIILDKLLKRLKEKGSRVLIFSQMSRLLDILEDYCYFRDFEYCRIDGSTSHEERIEAIDEYNKPNSEKFVFLLTTRAGGLGINLVTADTVILFDSDWNPQADLQAMDRAHRIGQKKQVHVYRFVTENAIEEKVIERAAQKLRLDQLVIQQGT--GKKTASLGNSKDDLLDMIQFGAKNMFEKKASKVTV------------DADIDDILKKGEQKTQELNAKYQSLGLDDLQKFNGIE-----NQSAYEWNGKSFQKKSND-KVVEWIN-PSRRERRREQTTYSVDDYYKEIIGGGSKSASKQTPQPKAPRAPKVIHGQDFQFFPKELDALQEKEQLYFKKKVNYKVTSYDITGDIRNEGSDAEEEEGEYKNAANTEGHKGHEELKRRIEEEQEKINSAPDFTQEDELRKQELISKAFTNWNKRDFMAFINACAKYGRDDMENIKKSIDS-KTPEEVEVYAKIFWERLKEINGWEKYLHNVELGEKKNEKLKFQETLLRQKIEQCKHPLHELIIQYPP-NNARRTYNTLEDKFLLLAVNKYGLRADKLYEKLKQEIMMSDLFTFDWFIKTRTVHELSKRVHTLLTLIVREY---EQPDANKKKRSRTSATREDTPLSQNESTRASTVPN--LPTTMVTNQKDTNDHVDKRTKIDQEA------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P38144-1", "uniprot_id": "ISW1_YEAST", "id": "P38144-1", "name": "ISWI chromatin-remodeling complex ATPase ISW1", "aln": "MAYMLAIANFHFFKFYTRMRKKHENNSCNEKDKDENLFKIILAIFLQEKKKYDCISSGSIMTASEEYLENLKPFQVGLPPHDPESNKKRYLLKDANGKK--FDLEGTTKRFEHLLSLSGLFKHFIESKAAKDP---KFRQVLDVLEENKANGKGKGKHQDVRRRKTEHEEDAELLKEEDSDDDESIEFQFR--ESPAYVN-GQLRPYQIQGVNWLVSLHKNKIAGILADEMGLGKTLQTISFLGYLRYIEKIPGPFLVIAPKSTLNNWLREINRWTPDVNAFILQGDKEERAELIQKKLLGCDFDVVIASYEIIIREKSPLKKINWEYIIIDEAHRIKNEESMLSQVLREFTSRNRLLITGTPLQNNLHELWALLNFLLPDIFSDAQDFDDWFSSESTEEDQDKIVKQLHTVLQPFLLRRIKSDVETSLLPKKELNLYVGMSSMQKKWYKKILEKDLDAVNGSNGSKESKTRLLNIMMQLRKCCNHPYLFDGAEPGPPYTTDEHLVYNAAKLQVLDKLLKKLKEEGSRVLIFSQMSRLLDILEDYCYFRNYEYCRIDGSTAHEDRIQAIDDYNAPDSKKFVFLLTTRAGGLGINLTSADVVVLYDSDWNPQADLQAMDRAHRIGQKKQVKVFRLVTDNSVEEKILERATQKLRLDQLVIQQNRTSLKKKENKADSKDALLSMIQHGAADVFKSGTSTGSAGTPEPGSGEKGDDIDLDELLLKSENKTKSLNAKYETLGLDDLQKFNQDS--------AYEWNGQDFKKKIQRDIISPLLLNPTKRERK---ENYSIDNYYKDVLN------TGRSSTPSHPRMPKPHVFHSHQLQPPQLKVLYEKERMWTAKKTGYVPT-------MDDVKAAYG-------DISDEE------EKKQKLELLKLSVNNSQPLTEEEEKMKADWESEGFTNWNKLEFRKFITVSGKYGRNSIQAIARELAPGKTLEEVRAYAKAFWSNIERIEDYEKYLKIIENEEEKIKRVKMQQEALRRKLSEYKNPFFDLKLKHPPSSNNKRTYSEEEDRFILLMLFKYGLDRDDVYELVRDEIRDCPLFELDFYFRSRTPVELARRGNTLLQCLEKEFNAGIVLDDATKDRMKKEDENGKRIREEFADQTANEKENVDGVESKKAKIEDTSNVGTEQLVAEKIPENETTH", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . :. . . ... : . . .**..** : :* **: : : . . . . ::*:**:*** **: :.. . : **:::: *::* **::*:**::**::* : *****************:***::: .: **.:::.*****.** *: :* * :. . * **:: * :::. :: :** ::***: *:**. :*:: *.*::**********:* **:::* * : ****:*************:********:*..:: **.**. :. *: :: :** **.******:*::**. * ** * :::**::.** .**. :* **:* :*.: : * ** **:****** ******:*********** **: *:.*: :***** :*:*:**********:*:******** :*:::***:**.*.*::* *: :* :* **:*:*:**********.:**.*:::******* *************.* *:*:*::*:.::**:::*** *****.:*** . . .** :*.:*:.** .:* . : : * *:* :* :. ** . : ..:* ..*:.*. .*:::*:.:::* : . : *.:***: .*::* *::: : .. *. ** ** :..*: * .* * ::* : *. .* . . : :. : . : .::.: :.:*: * . ::.** *.* :* **.. *:**:.:: * :.: ** *** * **.. .::. *: : :* * : :: : * *: . : *:.:* :.: .* :.*. **:*:: : * *: :.:*: :: * . * :*:::::** ** :* :**: : :* : : . :. . : : . . : . ", "identical_positions": 359, "similar_positions": 326, "identity": "30.58%" }, { "cls_id": "homologset.agr.RGD:1308833", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8NHZ7-1", "uniprot_id": "MB3L2_HUMAN", "id": "Q8NHZ7-1", "name": "Methyl-CpG-binding domain protein 3-like 2", "aln": "MGEPAFTSFPSLPVLGKLKRNMMPWALQKKREIHMAKAHRRRAARS----ALPMRLTSCIFRRPVTRIRSHPDNQVRRRKGDEHLEKPQQLCAYRRLQALQPCSSQGEGSSPLHLESVLSILAPGTAGESLDRAGAERVRSPLEPTPGRFPAVAG--------GPTPG-MGCQLPPPLSG------QLVTPADIRRQARRVKKARERLAKALQADRLARRAEMLTGG-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A1B0GVZ6-1", "uniprot_id": "MB3LB_HUMAN", "id": "A0A1B0GVZ6-1", "name": "Methyl-CpG-binding domain protein 3-like 2B", "aln": "MGEPAFTSFPSLPVLGKLKRNMMPWALQKKREIHMAKAHRRRAARS----ALPMRLTSCIFRRPVTRIRSHPDNQVRRRKGDEHLEKPQQLCAYRRLQALQPCSSQGEGSSPLHLESVLSILAPGTAGESLDRAGAERVRSPLEPTPGRFPAVAG--------GPTPG-MGCQLPPPLSG------QLVTPADIRRQARRVKKARERLAKALQADRLARRAEM-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A6NDZ8-1", "uniprot_id": "MB3L4_HUMAN", "id": "A6NDZ8-1", "name": "Methyl-CpG-binding domain protein 3-like 4", "aln": "MGEPAFTSFPSPPVLGKLKRNMMPWALQKKREIHMAKAHRRRAARS----ALPMRLTSCIFRRPVTRIRSHPDNQVRRRKGDEHLEKPQQLCAYRRLQALQPCSSQGEGSSPLHLESVLSILAPGTAGESLDRAGAERVRIPLEPTPGRFPAVAG--------GPTPG-MGCQLPPPLSG------QLVTPADIRRQARRVKKARERLAKALQADRLARQAEMLTCR-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A6NJ08-1", "uniprot_id": "MB3L5_HUMAN", "id": "A6NJ08-1", "name": "Methyl-CpG-binding domain protein 3-like 5", "aln": "MGEPAFTSFPSPPVLGKLKRNMMPWALQKKREIHMAKAHRRRAARS----ALPMRLTSCIFRRPVTRIRSHPDNQVRRRKGDEHLEKPQQLCAYRRLQALQPCSSQGEGSSPLHLESVLSILAPGTAGESLDRAGAERVRIPLEPTPGRFPAVAG--------GPTPG-MGCQLPPPLSG------QLVTPADIRRQARRVKKARERLAKALQADRLARQAEMLTGG-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZHU7-1", "uniprot_id": "D3ZHU7_RAT", "id": "D3ZHU7-1", "name": "", "aln": "MEEPSGNSVSSQPLLGRLTRNMIPNKLQKTRKIRVAQSKTKTKRRSGGTFKDPLRRTSCIFPQPVTLITSYSENKTRYRRDEAKLQKPEQLCALQRLENLQVGEEDRNLSCPLKLANPVETIVQGMQDEANNQSGDKDQLTPGQVTSDQPPCLETTEQGALQLSPSFSSQGVTMPVPLRLSPSYCLQEVTTADIQRQAWKVKKARKRLAEALEADRLARQAENMRETR", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* **: .*..* *:**:*.***:* ***.*:*::*::: : ** *:* ***** :*** * *:.:*:.* *:.: :*:**:**** :**: ** ..: : *.**:* . :. :. * .*: :::* : * : *..: *.: .*: . * :* ** * **.***:*** :*****:***:**:******:** ", "identical_positions": 89, "similar_positions": 65, "identity": "39.04%" }, { "cls_id": "homologset.agr.RGD:1308834", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q92997-1", "uniprot_id": "DVL3_HUMAN", "id": "Q92997-1", "name": "Segment polarity protein dishevelled homolog DVL-3", "aln": "-------MGETKIIYHLDGQETPYLVKLPLPAERVTLADFKGVLQRPS--YKFFFKSMDDDFGVVKEEISDDNAKLPCFNGRVVSWLVSAEGSHPDPAPFCADNP-SELPPPMERTGGIGDSRPPSFHPHAGGGSQENLDNDTETDSLVSAQRERPRRRDGPEHATRLNGTAKGERRREPGGYDSSSTLMSSELETTSFFDSDEDDSTSRFSSSTEQSSASRLMRRHKRRRRKQKVSRIERSSSFSSITDSTMSLNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAVRVLREIVHKPGPITLTVAKCWDPSPRGCFTLPRSEPIRPIDPAAWVSHTAAMTGTFPAYGMSPSLSTITSTSSSITSSIPDTERLDDFHLSIHSDMAAIVKAMASPESGLEVRDRMWLKITIPNAFIGSDVVDWLYHNVEGFTDRREARKYASNLLKAGFIRHTVNKITFSEQCYYIFGDLCGN--MANLSLHDHDGSSGAS-DQDTLAPLPHPGAAPWPMAFPYQYPPPPHPYNPHPGFPELGYSYGGGSASSQHSEGSRSSGSNRSGSDRRKEKDPKAGDSKSGGSGSESDHTTRSSLRGPRERAPSERSGPAASEHSHRSHHSLASSLRSHHTHPSYGPPGVPPLYGPPMLMMPPPPAAMGPPGAPPGRDLASVPPELTASRQSFRMAMGNPSEFF--VDVM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q61062-1", "uniprot_id": "DVL3_MOUSE", "id": "Q61062-1", "name": "Segment polarity protein dishevelled homolog DVL-3", "aln": "-------MGETKIIYHLDGQETPYLVKLPLPAERVTLADFKGVLQRPS--YKFFFKSMDDDFGVVKEEISDDNAKLPCFNGRVVSWLVSAEGSHPEPAPFCADNP-SELPPSMERTGGIGDSRPPSFHPHASGGSQENLDNDTETDSLVSAQRERPRRRDGPEHAARLNGTTKGERRREPGGYDSSSTLMSSELETTSFFDSDEDDSTSRFSSSTEQSSASRLMRRHKRRRRKQKVSRIERSSSFSSITDSTMSLNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAVRVLREIVHKPGPITLTVAKCWDPSPRGCFTLPRSEPIRPIDPAAWVSHTAAMTGTFPAYGMSPSLSTITSTSSSITSSIPDTERLDDFHLSIHSDMAAIVKAMASPESGLEVRDRMWLKITIPNAFIGSDVVDWLYHNVEGFTDRREARKYASNLLKAGFIRHTVNKITFSEQCYYIFGDLCGN--MANLSLHDHDGSSGAS-DQDTLAPLPHPGAAPWPMAFPYQYPPPPHPYNPHPGFPELGYSYGGGSASSQHSEGSRSSGSNRSGSDRRKEKDPKAGDSKSGGSGSESDHTTRSSLRGPRERAPSERSGPAASEHSHRSHHSLTSSLRSHHTHPSYGPPGVPPLYGPPMLMMTPPPAAMGPPGAPPGRDLASVPPELTASRQSFRMAMGNPSEFF--VDVM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4ADV8-1", "uniprot_id": "D4ADV8_RAT", "id": "D4ADV8-1", "name": "", "aln": "-------MGETKIIYHLDGQETPYLVKLPLPAERVTLADFKGVLQRPS--YKFFFKSMDDDFGVVKEEISDDNAKLPCFNGRVVSWLVSAEGSHPEPAPFCADNP-SELPPSMERTGGIGDSRPPSFHPHASGGSQENLDNDTETDSLVSAQRERPRRRDGPEHAARLNGTTKGERRREPGGYDSSSTLMSSELETTSFFDSDEDDSTSRFSSSTEQSSASRLMRRHKRRRRKQKVSRIERSSSFSSITDSTMSLNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAVRVLREIVHKPGPITLTVAKCWDPSPRGCFTLPRSEPIRPIDPAAWVSHTAAMTGTFPAYGMSPSLSTITSTSSSITSSIPDTERLDDFHLSIHSDMAAIVKAMASPESGLEVRDRMWLKITIPNAFIGSDVVDWLYHNVEGFTDRREARKYASNLLKAGFIRHTVNKITFSEQCYYIFGDLCGN--MANLSLHDHDGSSGAS-DQDTLAPLPHPGAAPWPMAFPYQYPPPPHPYNPHPGFPELGYSYAGGSASSQHSEGSRSSGSNRSGSDRRKEKDPKAGDSKSGGSGSESDHTTRSSLRGPRERAPSERSGPAASEHSHRSHHSLTSSLRSHHTHPSYGPPGVPPLYGPPMLMMTPPPAAMGPPGAPPGRDLASVPPELTASRQSFRMAMGNPTKNFGLFDFL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P51140-1", "uniprot_id": "DSH_DROME", "id": "P51140-1", "name": "Segment polarity protein dishevelled", "aln": "MDADRGGGQETKVIYHIDDETTPYLVKIPIPSAQVTLRDFKLVLNKQNNNYKYFFKSMDADFGVVKEEIADDSTILPCFNGRVVSWLVSADGTNQSDN--CSELPTSECELGMGLTNRKLQQQQQQHQQQQQQQQQQHQQQQQQQQQQVQPVQLAQQQQQQVLHHQKMMGNP--LLQPPPLTYQSAS-VLSSDLDSTSLFGTESELTLDR--DMTDYSSVQRLQVRKKPQRRKKRAPSMSRTSSYSSITDSTMSLNIITVSINMEAVNFLGISIVGQSNRGGDGGIYVGSIMKGGAVALDGRIEPGDMILQVNDVNFENMTNDEAVRVLREVVQKPGPIKLVVAKCWDPNPKGYFTIPRTEPVRPIDPGAWVAHTQALT---------SHDSIIADIAEPIK------ERLD------QNNLEEIVKAMTKPDSGLEIRDRMWLKITIPNAFIGADAVNWVLENVEDVQDRREARRIVSAMLRSNYIKHTVNKLTFSEQCYYVVNEERNPNLLGRGHLHPHQLPHGHGGHALSHADTESITSDIGPLPNPPIYMPYSATYNPSHGYQPIQY----GIAERHISSGS-------SSSDVLTSKDISASQSDITSVIHQANQLTIAAHGSNKSSGSSNRGGGGGGGGGGNNTNDQDVSVFNYVL---------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***:***:*.: ******:*:*: :*** *** **:: . **:****** *********:**.: ***************:*:: . *:: * ** * *. :.: ..: : .*:: ::: : :. *.. : :::: * :: *.. : * *:*:* ::**:*::**:*.::.: : .* . *: **..** *:* :***::.. :.*:**:***************::*** ************. ******:********** *********:****::*****:**:*******:*:*****.*.*******.*:* **:**:**:*****.***:** *:* . * *:. :..*. **** :.:: *****:.*:****:****************:*.*:*: .***.. ******: .* :*::.:*:*****:********:..: . :.. ** *: . * . . : * : *:. * * * . .*** *: : * * *. : *.** *.** ..** .*.:*. . :::: * :: . :. ..*:*.* ... . .. :. *: .: ", "identical_positions": 291, "similar_positions": 186, "identity": "39.81%" }, { "cls_id": "homologset.agr.RGD:1308835", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LRH5-1", "uniprot_id": "A0ABK0LRH5_RAT", "id": "A0ABK0LRH5-1", "name": "", "aln": "MLRKRSPASQPQGFRGESEALLGEAAVCSRSSRGRLRFEPSPDLARHHLPAPPMLGAPESGDHSGEGATRTPRMDARTWRLGWRCLLLLALLGSTRSEGVESCEEVRKLFQWRLGGAVKGLPEAPRAGPDLQVCLSKNPTCCTRKMEEQYQIAAQQDLQQVLQTSSSTLKLLISRNAAAFQETLETLIRQAENYTSILFCNTYRNMALEAAASTQEFFTDVGLYLFG------------------ADVNPEEFVNRFFDSLFPLVYNHLINPG---VTDSSLQYSECIRTARQDVSPFGNIPKRVMGQMGRSLLPGRTFLQALNLGIEVINTTDHIH---FSKECSRALLKMQYCPHCQSLTLS-----KPCMGYCLNVIRGCLAHMT-DLNPHWHAYIRSLEELS-DAMHGTYDVEHVLLNFHLLVNDAMLQAHLNAQKLLDQVNKICGLPVRTATQSPRCTFDPSKERHGMKISPRNGEETLANRRKEFINSLRLHRSFYGGLADQLCVNEWAAAEGRPCWNGEDIVKSYAQRVVGNGVKAQSANPEVRVRGTDP--VVNQIIDKLKHVIQLLQGRSP----KPNKWELLHPGSGGGMLEQSSGDCDDEDGCGGSGSGEVKRTLKITNWMPDSMNFSDVKQVHGADRGSTLDTTGAGCGSGTESMTLLLMGTLMFLPWLW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CAL5-1", "uniprot_id": "GPC5_MOUSE", "id": "Q8CAL5-1", "name": "Glypican-5", "aln": "-------------------------------------------------------------------------MDARTWRLGWRCLLLLALLGSTRSEGVESCEEVRKLFQWRLGGAVKGLPEAPRAGPDLQVCLSKNPTCCTRKMEERYQIAARQDLQQVLQTSSSTLKLLISRNAAAFQETLETLIRQAENYTSILFCNTYRNMALEAAASIQEFFTDVGLYLFG------------------ADVNPEEFVNRFFDSLFPLVYNHLINPG---VTDSSLQYSECIRMARQDVSPFGNIPKRVMGQMGRSLLPGRTFLQALNLGIEVINTTDHIH---FSKECSRALLKMQYCPHCQSLMLS-----KPCMGYCLNVIRGCLAHMT-ELNPHWHAYIRSLEELS-DAMHGTYDVEHVLLNFHLLVNDAVLQAHLNGQKLLDQVNTICGHPVRTPTQSPRCTFDPSKEKHGMKISARNGEETLANRRKEFINSLRLHGSFYGGLADQLCVNELAAPEGRPCWNGEEIVKSYAQRVVGNGIKAQSANPEVRVRGTDP--VVNQIIDKLKHVIQLLRGRSP----KPNKWELLQPGSGGGMLENSSGDCDDEDGCGGSGSGEVKRTLKITNWMPDSMNFSDVKQVHRADHGSTLDTTSTGCASGTESMALPLMGTLMFLPWLW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P78333-1", "uniprot_id": "GPC5_HUMAN", "id": "P78333-1", "name": "Glypican-5", "aln": "-------------------------------------------------------------------------MDAQTWPVGFRCLLLLALVGSARSEGVQTCEEVRKLFQWRLLGAVRGLPDSPRAGPDLQVCISKKPTCCTRKMEERYQIAARQDMQQFLQTSSSTLKFLISRNAAAFQETLETLIKQAENYTSILFCSTYRNMALEAAASVQEFFTDVGLYLFG------------------ADVNPEEFVNRFFDSLFPLVYNHLINPG---VTDSSLEYSECIRMARRDVSPFGNIPQRVMGQMGRSLLPSRTFLQALNLGIEVINTTDYLH---FSKECSRALLKMQYCPHCQGLALT-----KPCMGYCLNVMRGCLAHMA-ELNPHWHAYIRSLEELS-DAMHGTYDIGHVLLNFHLLVNDAVLQAHLNGQKLLEQVNRICGRPVRTPTQSPRCSFDQSKEKHGMKTTTRNSEETLANRRKEFINSLRLYRSFYGGLADQLCANELAAADGLPCWNGEDIVKSYTQRVVGNGIKAQSGNPEVKVKGIDP--VINQIIDKLKHVVQLLQGRSP----KPDKWELLQLGSGGGMVEQVSGDCDDEDGCGGSGSGEVKRTLKITDWMPDDMNFSDVKQIHQTDTGSTLDTTGAGCAVATESMTFTLISVVMLLPGIW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24114-1", "uniprot_id": "DALY_DROME", "id": "Q24114-1", "name": "Division abnormally delayed protein", "aln": "-------------------------------------------MAARSVRLAQLLLFTLLCGFVGLSAAKHLDLDGIHHHQHHLHSATTHHRRRLQRDSRAKDAVGGSTHQCDAVKSYFESIDIKSSGTYSEKGAICGGNCCNNATELELRDKAAGMFEQLLHHHTSSLRGVLETNAKQFQSHVLELAQISENMTHSLFSKVYTRMVPSSRMMIHQLYTEIMNHLIYTSNYTNSNGQLGRRGIGSVQSNLEEAVRHFFVQLFPVAYHQMVHLSKNNLGDLHEDYVNCLQHNFDEMHPFGDIPQQVQSNLGKSVHMSNVFMNALLQAAEVLSEADALYGEQLTDTCKLHLLKMHYCPNCNGHHSSSRSETKLCYGYCKNVMRGCSAEYAGLLDSPWSGVVDSLNNLVTTHILSDTGIINVIKHLQTYFSEAIMAAMHNGPELEKKVKKTCGTPSLTPYSSGEPDARPPPHKNNVKWATDPDPGMVL-----FLSTIDKSKEFYTTIVDNFCDEQQHSRDDHSCWSG-DRFGDYTQLLINPGTDSQRYNPEVPFNAKAQTGKLNELVDKLFKIRKSIGAAAPSNSIQATHDIQNDMGEGSGGGEGQIGDDEEEYG-GAHGSGDGS-----GDGPHTPIEESEGTTTNEVESRDSGKTSGSNPLEGTATWMLLTLVTMLFSSCS-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*. : :. . . .* : : :*. : .**.. * . : * ::*.*: :*:*: ::. ** **. : * : :** * **...* .*. .: ::::*:: :*: .: * ** *.:** .***:.*::::: . : * :* :*:: :: ***:**::* .::*:*: ...*::** . **:. :* :: ::. *. ****:***:*:. : * * *** **:*** *. : *:. * . : **::* : . .: :*: ::: ..:*:: * *. :* .:*: ** * *. .* . . .::.:* :. . : *:.:: .** :.*::* :: : :. .**.* : . .*:* ::. * .:* **** ... :*:::*** :: : : . :* :. : . *.*.* * ** ::* * *. ***: . : :: *: . : .: .: .*:.:. .* : : : .::: . ", "identical_positions": 125, "similar_positions": 209, "identity": "18.33%" }, { "cls_id": "homologset.agr.RGD:1308836", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JW48-1", "uniprot_id": "A0A0G2JW48_RAT", "id": "A0A0G2JW48-1", "name": "", "aln": "MGHLGTDRPTLISCPLSAYWPLPAAGVSGSMVFCLENKMPHRLLGSAMVHFHASEVQQLLHNKFVVILGDSIQRAVYKDLVLLLQKDTLLTASQLKAKGELSFEQDQLVAGGQLGELHNGTQYREVRQFCSGSGHHLVRFYFLTRVYSEYLEDVLEELSYGPAPDLVIINSCLWDLSRYGRCSMESYRENLERVFVRMDQVLPDSCLLVWNLAMPLGERVTGGFLLPELQPLAVSLRQDVVEGNFYSATLAGNHCFDVLDLHFHFRHAVRHRHRDGVHWDQHAHRHLSHLLLTHVADAWGVELPKHDRLPDPWIEDWPEMDHSYQGSHKQPPDFREKPALPLLPPFHLPPPMSFPYPL-QPSPPPLFPPLPQDTPFFQGQPFPPYEFK-YNAMEDFSMP---GCGPGMNFVPGPLPPSVSGPVSHGQHRGPVVHRGKPRCVLNNPYHVPRIGGPCRHRLRHSDRLIHTYKQDRRGYAHSGTWPG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P1Z5-1", "uniprot_id": "PED1A_MOUSE", "id": "Q6P1Z5-1", "name": "PC-esterase domain-containing protein 1A", "aln": "------------------------------MVFCLENEMPHRLLGSAMVHFHASEVQQLLHNKFVVILGDSIQRAVYKDLVLLLQKDTLLTASQLKAKGELSFEQDQLVAGGQLGELHNGTQYREVRQFCSGSGHHLVRFYFLTRVYSEYLEDILEELSYGPAPDLVIINSCLWDLSRYGRCSMESYRENLERVFVRMDQVLPDSCLLVWNLAMPLGERVTGGFLLPELQPLAVSLRQDVVEGNFYSATLAGKHCFDVLDLHFHFRHAVRHRHRDGVHWDQHAHRHLSHLLLAHVADAWGVELPKHDRLPDPWIEDWSEMDHSFQGSHKQPPDFREKLALPLLPPFHLPPPMSFPYPL-EPSPPPLFPPLPQDTPFFQGQPFPPYEFK-YNAMEDFSMP---GCGPGMNFVPGPLPPSVSGPVSHGQHRGPVVHRGKPRCVLNNPYHVPRIGGPCRHRLRHSDRLIHTYKQDRRGHAHSGTWPG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H1Q7-1", "uniprot_id": "PED1A_HUMAN", "id": "Q9H1Q7-1", "name": "PC-esterase domain-containing protein 1A", "aln": "------------------------------MVFCLSSEEPRRPLRSDMVHFQASEVQQLLHNKFVVILGDSIQRAVYKDLVLLLQKDSLLTAAQLKAKGELSFEQDQLVAGGQLGELHNGTQYREVRQFCSGSGHHLVRFYFLTRVYSEYLEDVLEELTYGPAPDLVIINSCLWDLSRYGRCSMESYRENLERVFVRMDQVLPDSCLLVWNMAMPLGERITGGFLLPELQPLAGSLRRDVVEGNFYSATLAGDHCFDVLDLHFHFRHAVQHRHRDGVHWDQHAHRHLSHLLLTHVADAWGVELPKRGYPPDPWIEDWAEMNHPFQGSHRQTPDFGEHLALLPPPPSSLPPPMPFPYPLPQPSPPPLFPPLPQDTPFFPGQPFPPHEFFNYNPVEDFSMPPHLGCGPGVNFVPGPLPPPIPGPNPHGQHWGPVVHRGMPRYVPNSPYHVRRMGGPCRQRLRHSERLIHTYKLDRRPPAHSGTWPG", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *****..: *:* * * ****:***********************************:****:************************************************************:****:****************************************************:*******:************* ***:**************.****************:**********************:************:. ********.**:*.:****:*.*** *: ** ** *****.***** :***************** ******:** **.:****** *****:*********.:.** .**** ******* ** * *.**** *:*****:*****:******* *** ********", "identical_positions": 386, "similar_positions": 38, "identity": "79.75%" }, { "cls_id": "homologset.agr.RGD:1308837", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "B4F7F0-1", "uniprot_id": "B4F7F0_RAT", "id": "B4F7F0-1", "name": "Claudin", "aln": "MASTGLQILGIVLTLLGWVNALVSCALPMWKVTAFIGNSIVVAQMVWEGLWMSCVVQSTGQMQCKVYDSLLALPQDLQAARALCVITLLIVLLGLLLYLAGAKCTTCVEDKNSKSRLVLISGVIFVISGVLTLIPICWTAHAIIQDFYNPLVADAQKRELGASLYLGWAASGLLLIGGGLLCCACSSGGTQGPSHYVARYSSPVP-HSRGPSEYPSKNYV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z262-1", "uniprot_id": "CLD6_MOUSE", "id": "Q9Z262-1", "name": "Claudin-6", "aln": "MASTGLQILGIVLTLLGWVNALVSCALPMWKVTAFIGNSIVVAQMVWEGLWMSCVVQSTGQMQCKVYDSLLALPQDLQAARALCVVTLLIVLLGLLVYLAGAKCTTCVEDRNSKSRLVLISGIIFVISGVLTLIPVCWTAHSIIQDFYNPLVADAQKRELGASLYLGWAASGLLLLGGGLLCCACSSGGTQGPRHYMACYSTSVP-HSRGPSEYPTKNYV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P56747-1", "uniprot_id": "CLD6_HUMAN", "id": "P56747-1", "name": "Claudin-6", "aln": "MASAGMQILGVVLTLLGWVNGLVSCALPMWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTGQMQCKVYDSLLALPQDLQAARALCVIALLVALFGLLVYLAGAKCTTCVEEKDSKARLVLTSGIVFVISGVLTLIPVCWTAHAIIRDFYNPLVAEAQKRELGASLYLGWAASGLLLLGGGLLCCTCPSGGSQGPSHYMARYSTSAPAISRGPSEYPTKNYV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:*:****:*********.***********************:****************************************::**:.*:***:************:::**:**** **::***********:*****:**:********:*********************:*******:*.***:*** **:* **:..* ********:****", "identical_positions": 185, "similar_positions": 30, "identity": "84.09%" }, { "cls_id": "homologset.agr.RGD:1308838", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZLV8-1", "uniprot_id": "A0A8I5ZLV8_RAT", "id": "A0A8I5ZLV8-1", "name": "", "aln": "MNSSHSFNQTYSASVHSLGSTWGQRGSCHRTPSVHGGAGGVRISLSFTTPGCLPPGGSWGSGRSSPLLGGNGKATMQNLNDRLASYLEKVRALEEANSKLESRILQWHQEREPSTKKDYSQYEENISHLQEQIVDGKMANAHIVVLIDNARMAVDDFNLKFENEHSLKKDLEIEVEGLRKTLDDLTIVTTDLEQEVEGMRKELILMKKRHEQEMEENHWPSDFKVNVKVDTTPGEDLIKVLEDMRQEYELIIKKKHQELDTWFREQSASMAQGVASPVPVQGSQSDIHELRRTFQALEIDLQAQHNRKSALENMLTETQARYSCRLQDMQQIISHYEEELIQLRQDLERQNNEHKVLLGIKTHLEKEIATYRRLLEGDTEGTRDEPESRLKGSPASMIKAITQESVNGRIVLSQVNEIQKHL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99PS0-1", "uniprot_id": "K1C23_MOUSE", "id": "Q99PS0-1", "name": "Keratin, type I cytoskeletal 23", "aln": "MNSSHSFNQTYSASVHSLGSTRGRQGSCHRAPSVHGGAGGVRISLSFTTPGCLPPGGSWGSGRSSPLLGGNGKATMQNLNDRLATYLEKVRALEEANSKLETRILRWHQEREPSHRKDYSQYEENISRLQEQIVDGKMANAHIVVLIDNARMAVDDFNLKFENEHSLKKDLEIEVEGLRKTLDDLTIVTTDLEQEVEGMRKELILMKKRHEQEMEENHLPSDFKVSVKVDTTPGEDLIKVLEDMRQEYELIIKKKHQELDTWFREQSAAMAQEVASPAPVQGNQSDIHELRRTFQALEIDLQAQHSRKTALENMLTETRARYSCRLQDMQQIISHYEEELIQLRQDLERQNNEHKVLLGIKTHLEKEIATYRRLLEGDTEGTMDGSESRLKGSEASTIKAITQESVNGRIVLSQVNEIQKHI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9C075-1", "uniprot_id": "K1C23_HUMAN", "id": "Q9C075-1", "name": "Keratin, type I cytoskeletal 23", "aln": "MNSGHSFSQTPSASFHGAGGGWGRPRSFPRAPTVHGGAGGARISLSFTTRSCPPPGGSWGSGRSSPLLGGNGKATMQNLNDRLASYLEKVRALEEANMKLESRILKWHQQRDPGSKKDYSQYEENITHLQEQIVDGKMTNAQIILLIDNARMAVDDFNLKYENEHSFKKDLEIEVEGLRRTLDNLTIVTTDLEQEVEGMRKELILMKKHHEQEMEKHHVPSDFNVNVKVDTGPREDLIKVLEDMRQEYELIIKKKHRDLDTWYKEQSAAMSQEAASPATVQSRQGDIHELKRTFQALEIDLQTQYSTKSALENMLSETQSRYSCKLQDMQEIISHYEEELTQLRHELERQNNEYQVLLGIKTHLEKEITTYRRLLEGESEGTREESKSSMKVSATPKIKAITQETINGRLVLCQVNEIQKHA", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***.***.** ***.*. *. *: * *:*:*******.******** .* *******************************:************ ***:***:***:*:*. :**********::**********:**:*::***************:*****:************:***:************************:******::* ****:*.***** * **********************::****::****:*:* .***..**. *.*****:***********:*:. *:******:**::****:*****:********* ***::*******::*************:********::*** : .:* :* * :. *******::***:**.******** ", "identical_positions": 326, "similar_positions": 70, "identity": "77.25%" }, { "cls_id": "homologset.agr.RGD:1308839", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QYM9-1", "uniprot_id": "TEFF2_MOUSE", "id": "Q9QYM9-1", "name": "Tomoregulin-2", "aln": "MVLWESPRQCSSWTLCEGFCWLLLLPVTLLIIARPVK-LAAFPTSLSDCQTPTGWNCSGYDDRENDLFLCDTNTCKFDGECLRIGDTVTCVCQFKCNSDYVPVCGSNGESYQNECYLRQAACKQQSEILVVSEGSCAT---DTGSGSGDGVHEGSGETSQKETSTCDICQFGAECDEDAEDVWCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPSCRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GGQ4-1", "uniprot_id": "A0A8I6GGQ4_RAT", "id": "A0A8I6GGQ4-1", "name": "Tomoregulin-2", "aln": "MVLWESPRQCSSWTLCEGFCWLLLLPVTLLIIARPVK-LAAFPTSLSDCQTPTGWNCSGYDDRENDLFLCDTNTCKFDGECLRIGDTVTCVCQFKCNSDYVPVCGSNGESYQNECYLRQAACKQQSEILVVSEGSCAT---DAGSGSGDGVHEGSGETSQKETSTCDICQFGAECDEDAEDVWCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPSCRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UIK5-1", "uniprot_id": "TEFF2_HUMAN", "id": "Q9UIK5-1", "name": "Tomoregulin-2", "aln": "MVLWESPRQCSSWTLCEGFCWLLLLPVMLLIVARPVK-LAAFPTSLSDCQTPTGWNCSGYDDRENDLFLCDTNTCKFDGECLRIGDTVTCVCQFKCNNDYVPVCGSNGESYQNECYLRQAACKQQSEILVVSEGSCAT---DAGSGSGDGVHEGSGETSQKETSTCDICQFGAECDEDAEDVWCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPSCRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BD12-1", "uniprot_id": "A0A8M2BD12_DANRE", "id": "A0A8M2BD12-1", "name": "", "aln": "MALCAVLRQTRRPPRQENRTHVVLITTYCFFCISPLKQLCAFPSSLSDCQTPTGWNCSGFEEQDTDLFLCDTNTCKFDGECLRIGDTVTCICDFKCSGDYAPVCGSNGESYENHCLLRKDACKLQTEVLVVSDGACPVGTRDAGSGSGDDANEGSAEISQKETSTCDICQFGAECDEDSEDVWCVCNIDCSHISFNPVCASDGRSYDNPCQVKEVSCQKQERIEVKYLGHCK--------------------EEKDQVSEVPWGLYIPCPERYKDYCVHGECEYPSNLSPPTCSCHSGFIGPQCDRKDYNVMYVVPGSGKLRYVLIASIIGALQVAIICLVVLCITRRCPRGNRIARQKQNVPHFNSENTLRASTRLI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.* ** . *. ::*:.. :: *:* *.***:***************:::::.*************************:*:***..**.**********:*.* **: *** *:*:****:*:*.. *:******..:***.* ********************:************: .***:*****:****.**:**.******:*** **:*: *: :::.* . :*****:*:.:*:**:**:. *:. *:* *.:*: * :*::***.*:*****. :::*****::**::*:*:**:*******:***.*** *****. *:.*:** *******", "identical_positions": 223, "similar_positions": 92, "identity": "58.99%" }, { "cls_id": "homologset.agr.RGD:1308840", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Y2E5-1", "uniprot_id": "MA2B2_HUMAN", "id": "Q9Y2E5-1", "name": "Epididymis-specific alpha-mannosidase", "aln": "MGQLCWLPLLAPLLLLRPPGVQSAGPIRAFVVPHSHMDVGWVYTVQESMRAYAANVYTSVVEELARGQQRRFIAVEQEFFRLWWDGVASDQQKYQVRQLLEEGRLEFVIGGQVMHDEAVTHLDDQILQLTEGHGFLYETFGIRPQFSWHVDPFGASATTPTLFALAGFNAHLGSRIDYDLKAAMQEARGLQFVWRGSPSLSERQEIFTHIMDQYSYCTPSHIPFSNRSGFYWNGVAVFPKPPQDGVYPNMSEPVTPANINLYAEALVANVKQRAAWFRTPHVLWPWGCDKQFFNASVQFANMDPLLDHINSHAAELGVSVQYATLGDYFRALHALNVTWRVRDHHDFLPYSTEPFQAWTGFYTSRSSLKGLARRASALLYAGESMFTRYLWPAPRGHLDPTWALQQLQQLRWAVSEVQHHDAITGTESPKVRDMYATHLASGMLGMRKLMASIVL------------DELQPQAPMAASSDAGPAGHFASVYNPLAWTVTTIVTLTVGFPGVRVTDEAGHPVPSQIQNSTETPSAYDLLILTTIPGLSYRHYNIRPTAG-AQEGTQEPAATVASTLQFGRRLRRRTSHAGRYLVPVANDCYIVLLDQDTNLMHSIWERQSNRTVRVTQEFLEYHVNGDVKQGPISDNYLFTPGKAAVPAWEAVEMEIVAGQLVTEIRQYFYRNMTAQNYTYAIRSRLTHVPQGHDGELLCHRIEQEYQAGPLELNREAVLRTSTNLNSQQVIYSDNNGYQMQRRPYVSYVNNSIARNYYPMVQSAFMEDGKSRLVLLSERAHGISSQGNGQVEVMLHRRLWNNFDWDLGYNLTLNDTSVVHPVLWLLLGSWSLTTALRQRSALALQHRPVVLFGD----LAGTAPKLPGPQQQEAVTLPPNLHLQILSIPGWRYSSNHTEHSQNLRKGHRGEAQADLRRVLLRLYHLYEVGEDPVLSQPVTVNLEAVLQALGSVVAVEERSLTGTWDLSMLHRWSWRTGPGRHRGDTTSPSRPPGGPIITVHPKEIRTFFIHFQQQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O54782-1", "uniprot_id": "MA2B2_MOUSE", "id": "O54782-1", "name": "Epididymis-specific alpha-mannosidase", "aln": "MGPLRWLPLLGQLLLLWPRAAQPAGPIRAFVVPHSHMDVGWVFTVQESMRAYAANVYTTVVAELVRGGQRRFIAVEQEFFRLWWDGVASEQQKQQVRQLLHEGRLEFVLGGQVMHDEAVTHLDDQILQLTEGHGFLYETFGIRPQFSWHVDPFGASATTPTLFALAGFNAHLISRIDYDLKDAMQEAQMLQFVWHGSPSLSGQQEIFTHVMDHYSYCTPSHIPFSNRSGFYWNGVAVFPEPPPDGVYPNMSEPVTGANIHLYAEALVANVKQRAAWFRTPHVLWPWGCDKQFFNASVQFDNMDPLLDYINQRTAQFGISVQYATLNDYFQALHATNMTWGIRDHQDFLPYSSEPLQAWTGFYTSRSTLKGLARQASALLYAGESMFTRYMWPDPSGTLDPTWALQQLQQLRWAVSEVQHHDAITGTESPKVKNMYTEHLRMGMLGVRKLMVSIALGGPPGSGTGAPKDIMGPQVTPVLSVDTRPVGYSASVYNPLAWKITTIITLTVAFPNVSVTDELGHPVSTQIQNSTKDPSAYDLLILTTIPGLNYRHYQVMHARG-DQAGTRELVAPRANTLKFSLKLRNQPSQEGKRLVPVMNDCYILLFDQDTNMLHSIQDRQSNRTVRMTQEFLEYQANWDVKQGPISDNYLFAPNNTAEPSWEAVGMEMVAGTLVTDIRQYFYRYITDQEYIYSIHTRLAHP--SLAGELLCQRIEQQYRVGPLDLNREAILRTSSDLNSQQVLYSDNNGYQMQRRPYKAFKSNPIPRNYYPMVQSAFIEDDKSRLVLLAERPHGVSSQGNGQVEVMLHRRLWNNLAWDLKYNLTLNDTSIVHPVLWLMLGPKSTMTALHPRSGVALQHGPVVLLKE----LADEETPVHGPHNPWPVTLPPNLHLQILSVPGWTYSRSHAQHLRNLQRGHPEKPQANLQRVLLRLRHLYEAGEDPVLSRPATVDLKVVLRGLGSVVAVEERSLTGTWDVQMLQRWHWSTKTDHLKGHPTSPPRPPGGSIITVYPKEIRTFFIKFQQ-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M1PZ41-1", "uniprot_id": "A0A8M1PZ41_DANRE", "id": "A0A8M1PZ41-1", "name": "Alpha-mannosidase", "aln": "----MIFPFFFGLLLMTVSENDAAEKIQAFVIPHSHMDVGWVYTVQESMHAYASNVYSTVVEELTRVKNRKFIAVEQEFFRLWWTNVASDWHKKQVRQLLLEGRLEFIIGGQVMHDEAVTDVDDAILQLTEGHGFLYETFGVRPRFAWHVDPFGASATTPVLFALAGFDAHLISRIDYDLKDDMQKNKKLQFVWRGSPTLKEKQEIFTHTMDQFSYCTPSYIPFSNRSGFYWNGVALFPDPPKDGKYPNMSLPVTKETVELYAQTMVDNIRLRAQWFRSSHVLWPWGCDKQFYNASVQFSNMDVLMNYINTHSDQYGVTVQYATLKDYFQTLHQTNLSWDVRGNQDFLPYSTEPFQAWTGFYGSRNVLKGVARRASSLLYASESLFTRYHISYPDGPVQREWALSKLKALRWAVSEVQHHDGITGTESPKVADMYMEHLLQGMMGAEELLAAIFLLPQTLSN--DIYDQIKNTPTTARTDSENVPEQHIFVYNPLAWNISTYVNVSVQYAMAVVLDDDGKAVPAQIQPSMESSTVYDLFFVVELGGLQYRKYTVQFPQSPCDTGSACGATHVAKVVKFNKTNVRQWKKTGRKLLPVLNECYKLMFDQETNLLHSITDRSKKIRVRVQQDFWEYKANGDVQSGPISDNYIFTANGSAVPAYKSVVMEIVPGKVISEIRQYFYREEEDANHTYSVVTRVPVG---FKGRLSCFRLEQSYKVGPLEVNRETVFRTRTSLQNNRTLFTDNNGYQMMKRTYKGYANNTVARNYYPMVRVAYMEDESSRVVFLSERAHGVASLSQGQLEVMLHRRLWNNQEWNQGYNLTLNDSSVVRPVLWMMLGSPDSLSSIYQQEAVELQHRPVVMAIDQPQKLLNQRETFSGP-SVHPVVLPQNLHMQSLSIPGWNYSPEHSS-------GGDEKSEVNFDRILLRITHLYEEGESPVLSQPTTINLKEVMQGIGKVSKVQECSLTGTWNISDLQRWNWKTDETMQKTDKSGFSGVTQDFNVTISPKEIRTFFIYF---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q5M820-1", "uniprot_id": "MOFA1_RAT", "id": "Q5M820-1", "name": "MORF4 family-associated protein 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRPLDAVELAEPEEVEVLE--------------PEEDFEQFLLPVIHEMREDIASLTRERGRAP-------VRNRGKLWEMDNMLIQIKTQVEASEESALNH---------LQGAGGAEPRGPRAEKADEKAQEMAKMAEMLVQLVRRIEKSESS-------------------------", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ..: * . * : * . * :* .:.. . :: :: .:*::: * .*...*.: ::. * . : .. . . : : : . : . ", "identical_positions": 10, "similar_positions": 43, "identity": "0.97%" }, { "cls_id": "homologset.agr.RGD:1308843", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4AAL3-1", "uniprot_id": "D4AAL3_RAT", "id": "D4AAL3-1", "name": "", "aln": "MFSWGLSCLSMLGAAGTALLCAGLLLGLAQQLWTLRWTLSRDWASTLPLPKGSMGWPFFGETLHWLVQGSRFHSSRRERYGTVFKTHLLGRPVIRVSGAENVRTILLGEHRLVRSQWPQSAHILLGSHTLLGAVGERHRQRRKVLARVFSRPALEQFVPRLQEALRREVRSWCAAQ---RPVAVYQAAKALT----FRMAARILLG--LQLDEARCTELAQTFERLVENLFSLPLDVPFSGLRKGIRARDQLYQHLDEVIAEKLREELTAEPGDALHLIINSARELGRELSVQELKELAVELLFAAFFTTASASTSLILLLLQHPAAIAKIQQELSAQGLGSPCSCAPRASG---------SRPDCSCEPDLSLAVLGRLRYVDCVVKEVLRLLPPVSGGYRTALRTFELDG----YQIPKGWSVMYSIRDTHETAAVYRSPPEGFDPERFGVESED-------ARGSGGR---------FHYIPFGGGARSCLGQELAQAVLQLLAVELVR----TARWELATPAFPVMQTVPIVHPVDGLLLLFHPLPTLGAGDGSPF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B2RXA7-1", "uniprot_id": "CP26C_MOUSE", "id": "B2RXA7-1", "name": "Cytochrome P450 26C1", "aln": "MISWGLSCLSVLGAAGTTLLCAGLLLGLAQQLWTLRWTLSRDWASTLPLPKGSMGWPFFGETLHWLVQGSRFHSSRRERYGTVFKTHLLGRPVIRVSGAENVRTILLGEHRLVRSQWPQSAHILLGSHTLLGAVGEPHRQRRKVLARVFSRSSLEQFVPRLQGALRREVRSWCAAQ---RPVAVYQAAKALT----FRMAARILLG--LQLDEARCTELAHTFEQLVENLFSLPLDVPFSGLRKGIRARDQLYEHLDEAVAEKLQEKQTAEPGDALLLIINSARELGHEPSVQELKELAVELLFAAFFTTASASTSLILLLLQHPAAITKIQQELSAQGLGRACTCTPRASG---------SPPDCGCEPDLSLAMLGRLRYVDCVVKEVLRLLPPVSGGYRTALRTFELDG----YQIPKGWSVMYSIRDTHETAAVYRSPPEGFDPERFGVESGD-------ARGSGGR---------FHYIPFGGGARSCLGQELAQAVLQLLAVELVR----TARWELATPAFPVMQTVPIVHPVDGLLLFFHPLPTSGAGDGLPF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6V0L0-1", "uniprot_id": "CP26C_HUMAN", "id": "Q6V0L0-1", "name": "Cytochrome P450 26C1", "aln": "MFPWGLSCLSVLGAAGTALLCAGLLLSLAQHLWTLRWMLSRDRASTLPLPKGSMGWPFFGETLHWLVQGSRFHSSRRERYGTVFKTHLLGRPVIRVSGAENVRTILLGEHRLVRSQWPQSAHILLGSHTLLGAVGEPHRRRRKVLARVFSRAALERYVPRLQGALRHEVRSWCAAG---GPVSVYDASKALT----FRMAARILLG--LRLDEAQCATLARTFEQLVENLFSLPLDVPFSGLRKGIRARDQLHRHLEGAISEKLHEDKAAEPGDALDLIIHSARELGHEPSMQELKESAVELLFAAFFTTASASTSLVLLLLQHPAAIAKIREELVAQGLGRACGCAPGAAGGSEG-----PPPDCGCEPDLSLAALGRLRYVDCVVKEVLRLLPPVSGGYRTALRTFELDG----YQIPKGWSVMYSIRDTHETAAVYRSPPEGFDPERFGAARED-------SRGASSR---------FHYIPFGGGARSCLGQELAQAVLQLLAVELVR----TARWELATPAFPAMQTVPIVHPVDGLRLFFHPLTPSVAGNGLCL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VYQ5-1", "uniprot_id": "CP318_DROME", "id": "Q9VYQ5-1", "name": "Probable cytochrome P450 318a1", "aln": "-----MHLNIALWACG--ALLAVLLAWQQRKCWRLIWQLN-GWRGVIQQP---VLWLLLCINLHPNSILEKVSQYR-VHFQRPLAVLVGTRVLLYIDDPAGMECVLNAPECLDKTFLQDGFFVRRG---LLHARGQKWKLRRKQLNPAFSHNIVASFFDVFNSVGNQMVEQFQTQTNLHGQAVKFTAAEDLLSRAVLEVSCLTIMGTPTNFTQLDDAHIAHSYKRLLE-ISAVRVVKPWLQIRLLHRLLAPELYEESKKCAKLLEDFVGGIVRTKHRNWRLRDAVGGEKSGEDASNGWQRRIFIEQIFQLAANGEMTLEEIMDEAQSMVLVSFETVSNSIMLALLCLATNKGDCQRRLLAEIRALVPDVGQVGLEQLQQLRYLDAFVSESLRLLATVPMNLRHVSRDFRLAGRQHETIVPQNSIVVLDTFNMQRDERWWGANARQFDPQRFLDQEEEQLSKGHNDSGSGEKRRQRDRRHSYSFLPFSNGLRSCIGRRYGLFIMKVFLVKLITNFDFQSDFELEKLQFVENISLKFKN-ADDILLTIQPKKEST-------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * *.* * * ** :: * * * *. . ..: * : * :: .** .:. . * :: : . : * :: :... .:. :* . . * :: :. .: * ** * *: : *** * .**: : :. :: . .: *..: : . : *:: * :.::. ::* .: : : :*:::::*:* : :: : *: :* * . . :: *.: . *.: . : : .::: :* *: . : :::.. ::. : * ::.: . * . * . ::.* * :***:*..*.* ****..*. . * . * *.* * :*:. *: . : :. : : .. ***:** : *:. : : ::**..* ***:*:. . ::::: *:*: : :** . * :: : : .*.: * ::* ", "identical_positions": 88, "similar_positions": 179, "identity": "15.71%" }, { "cls_id": "homologset.agr.RGD:1308844", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LVU1-1", "uniprot_id": "A0ABK0LVU1_RAT", "id": "A0ABK0LVU1-1", "name": "Copine-4", "aln": "MAVEPSNPESMKKRVGRRMKKMSNIYESAANTLGIFNSPCLTKVELRVACKGISDRDALSKPDPCVILKMQSHGQWFEVDRTEVIRTCINPVYSKLFTVDFYFEEVQRLRFEVHDISSNHNGLKEADFLGGMECTLGQIVSQRKLSKSLLKHGNTAGKSSITVIAEELSGNDDYVELAFNARKLDDKDFFSKSDPFLEIFRMNDDATQQLVHRTEVVMNNLSPAWKSFKVSVNSLCSGDPDRRLKCIVWDWDSNGKHDFIGEFTSTFKEMRGAMEGKQVQWECINPKYKAKKKNYKNSGMVILNQCKIHKMHSFLDYIMGGCQIQFTVAIDFTASNGDPRNSCSLHYIHPYQPNEYLKALVAVGEICQDYDSDKMFPAFGFGARIPPEYTVSHDFAINFNEDNPECAGIQGVVEAYQSCLPKLQLYGPTNIAPIIQKVAKSASEETNTKEASQYFILLILTDGVITDMADTREAIVHASHLPMSVIIVGVGNADFSDMQMLDGDDGILRSPKGEPVLRDIVQFVPFRNFKHASPAALAKSVLAEVPNQVVDYYNGKGIKPKCSSEVYESSRTLAP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BLR2-1", "uniprot_id": "CPNE4_MOUSE", "id": "Q8BLR2-1", "name": "Copine-4", "aln": "------------------MKKMSNIYESAANTLGIFNSPCLTKVELRVACKGISDRDALSKPDPCVILKMQSHGQWFEVDRTEVIRTCINPVYSKLFTVDFYFEEVQRLRFEVHDISSNHNGLKEADFLGGMECTLGQIVSQRKLSKSLLKHGNTAGKSSITVIAEELSGNDDYVELAFNARKLDDKDFFSKSDPFLEIFRMNDDATQQLVHRTEVVMNNLSPAWKSFKVSVNSLCSGDPDRRLKCIVWDWDSNGKHDFIGEFTSTFKEMRGAMEGKQVQWECINPKYKAKKKNYKNSGMVILNQCKIHKMHSFLDYIMGGCQIQFTVAIDFTASNGDPRNSCSLHYIHPYQPNEYLKALVAVGEICQDYDSDKMFPAFGFGARIPPEYTVSHDFAINFNEDNPECAGIQGVVEAYQSCLPKLQLYGPTNIAPIIQKVAKSASEETNTKEASQYFILLILTDGVITDMADTREAIVHASHLPMSVIIVGVGNADFSDMQMLDGDDGILRSPKGEPVLRDIVQFVPFRNFKHASPAALAKSVLAEVPNQVVDYYNGKGIKPKCSSEVYESSRTLAP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96A23-1", "uniprot_id": "CPNE4_HUMAN", "id": "Q96A23-1", "name": "Copine-4", "aln": "------------------MKKMSNIYESAANTLGIFNSPCLTKVELRVACKGISDRDALSKPDPCVILKMQSHGQWFEVDRTEVIRTCINPVYSKLFTVDFYFEEVQRLRFEVHDISSNHNGLKEADFLGGMECTLGQIVSQRKLSKSLLKHGNTAGKSSITVIAEELSGNDDYVELAFNARKLDDKDFFSKSDPFLEIFRMNDDATQQLVHRTEVVMNNLSPAWKSFKVSVNSLCSGDPDRRLKCIVWDWDSNGKHDFIGEFTSTFKEMRGAMEGKQVQWECINPKYKAKKKNYKNSGTVILNLCKIHKMHSFLDYIMGGCQIQFTVAIDFTASNGDPRNSCSLHYIHPYQPNEYLKALVAVGEICQDYDSDKMFPAFGFGARIPPEYTVSHDFAINFNEDNPECAGIQGVVEAYQSCLPKLQLYGPTNIAPIIQKVAKSASEETNTKEASQYFILLILTDGVITDMADTREAIVHASHLPMSVIIVGVGNADFSDMQMLDGDDGILRSPKGEPVLRDIVQFVPFRNFKHASPAALAKSVLAEVPNQVVDYYNGKGIKPKCSSEMYESSRTLAP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9QJ75-1", "uniprot_id": "E9QJ75_DANRE", "id": "E9QJ75-1", "name": "", "aln": "---------------------MSNIYESAATTLGIFNSPCLTKVELRVACKGISDRDALSKPDPCVVLKMQSHGQWFEVDRTEVIRSSISPVFSKVFTVDYYFEEVQRLRFELHDISSNHNGLKEADFLGAMECTLGQIVSQRKLSKALLKQGNTAGKSSITVTAEELSGNDDYVELAFSAKKLDDKDFFSKSDPFLEIFRVNDDGTASLVHRTETIMNNLSPVWKSFKVSLNTLCSGDHDRELKCIVWDWDSNGKHDFIGEFQTTFKEMKSAMDGKQIQWECINPKYQVKKKNYRNSGMVILTLCKIIKMHSFLDYIMGGCQIQFTVAIDFTASNGDPRNSCSLHYIHPYQPNEYLKALIAVGEICQDYDSDKMFPAFGFGAQIPPDFKVSHDFAVNFDEDNPECAGVQGVIEAYQNCLPKIQLYGPTNIAPIIQKVANSASEEMHTKEAMEYFILLILTDGVITDMADTREAIVHASHLPMSVIIVGIGSADFSDMQMLDGDDGILRSPKGEPVLRDIVQFVPFRNFKHASPAALAKSVLAEVPNQVVDYYNGKGIKPKGLSD-YESSRAFSP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *********.***********************************:*******************:.*.**:**:****:***********:*****************.****************:***:*********** ***************.*:*******************:***.* .******.:******.*******:*:***** **.******************** :*****:.**:***:*********:.*****:*** ***. *** ***************************************************:**********************:***::.******:**:********:***:****.****:****************:***** :**** :************************************:*.********************************************************************* *: *****:::*", "identical_positions": 490, "similar_positions": 52, "identity": "85.22%" }, { "cls_id": "homologset.agr.RGD:1308845", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZRL0-1", "uniprot_id": "A0A8I5ZRL0_RAT", "id": "A0A8I5ZRL0-1", "name": "Reversion-inducing cysteine-rich protein with Kazal motifs", "aln": "---------------------------------------------------------------------------MASVRASARGALLLLLSAAGVAKVTGGLAPGSAGAVCCNHSKDNQMCRDVCEQIFSSKSES-RLKHLLQRAPDYCPETMVEIWSCMNSSLPDLRLSPCLLFCSCSDMQNSSCLSPHCTGVFKKSDGWVGLGCCELAIGLECRQACKQASSKNDISKVCRKEYENALFSCISRNEMGSVCCSYAGHHTNCREFCQAIFRTDSSPGPSQIKAVENYCASISPQLIHCVNNYTQSYPMRNPTDSLYCCDRAEEHACQSACRRILTSKKTEMEIVDGLIEGCKTQ----PLPQDPLWQCFLESSQSVHPGVTVHP-------------------PPSTGLDGAKLHCCSKANTSVCRELCTKLYSMSWGNTQSWQEFDRICEYNPGEVSMLACLADVREPCQLGCTNLTYCTNFNNRPTELFRSCTAQSDQGAMSDMRLWE-KGSIKMPFISIPVLDIRTCQPDLWKAVACSLQIKPCHRKSRGSIICKSDCVEILKKCGDQNKFPEAHTAESICEFLSPADDVEN---CIPLDTYLRPSALGN-IIEEVTHPCNPNPCPANELCEVNRKGCPSGDPCLPYSCVQGCKLGEASDFIVRQGALIQVP---------SSAGEVGCYKICSCGQSGLLENCMEMHCIDLQKSCIVGGKRKSHGTSFTIDCNVCSCFAGNLVCSTRLCLSEHSSDDDRRAFTGLPCNCADQFVPVCAQNGRTYPSACIARCVGLQDHQFEFGPCISKDPCN---PNLCPKSQRCVPKPQVCLTTFDKFGCSQYECVPRQLT-CDQ-ARDPVCDTDHVEHSNLCTLYQRGKS--LSYRGPCQP--FCRTTEPVCGHNGETYSSVCAAYSDRVAVDYYGRCQAVGVLSEHSAVTECAAVKCPSLSAIGCKPIIPPGACCPLCAG-MLRVLFDKEKLDTIAKVTNKKP---ITVLEILQKIRMHVSVPQCDVFGYLSIESEIVILIIPVD--HYPKALQIEACNKEAEKIESLINSDSPTLASHVPLSALIISQVQVSSSLPSSAVVGRLPPVHSLPLFLSLGLTVHLLQTCP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z0J1-1", "uniprot_id": "RECK_MOUSE", "id": "Q9Z0J1-1", "name": "Reversion-inducing cysteine-rich protein with Kazal motifs", "aln": "---------------------------------------------------------------------------MASVRASPRSALLLLLAAAGVAEVTGGLAPGSAGAVCCNHSKDNQMCRDVCEQIFSSKSES-RLKHLLQRAPDYCPETMVEIWSCMNSSLP---------------------------GVFKKSDGWVGLGCCELAIGLECRQACKQASSKNDISKVCRKEYENALFSCISRNEMGSVCCSYAGHHTNCREFCQAIFRTDSSPGPSQIKAVENYCASISPQLIHCVNNYTQSYPMRNPTDSLYCCDRAEDHACQNACKRILMSKKTEMEIVDGLIEGCKTQ----PLPQDPLWQCFLESSQSVHPGVTVHP-------------------PPSTGLDGAKLHCCSKANTSTCRELCTKLYSMSWGNTQSWQEFDRICEYNPVEVSMLTCLADVREPCQLGCTNLTYCTNFNNRPTELFRSCTAQSDQGAMSDMKLWE-KGSIKMPFISIPVLDIKTCQPEMWKAVACSLQIKPCHSKSRGSIICKSDCVEILKKCGDQNKFPEEHTAESICEFLSPADDLES---CIPLDTYLRPSALGN-IIEEVTHPCNPNPCPANELCEVNRKGCPSADPCLPYSCVQGCKLGEASDFIVRQGTLIQVP---------SSAGEVGCYKICSCGQSGLLENCMEMHCIDLQKSCIVGGKRKSHGTSFTIDCNVCSCFAGNLVCSTRLCLSEHSSDDDRRTFTGLPCNCADQFVPVCAQNGRTYPSACIARCVGLQDHQFEFGPCISKNPCN---PNLCPKSQRCVPKPQVCLTTFDKFGCSQYECVPRQLT-CDQ-ARDPVCDTDHMEHSNLCTLYQRGKS--LSYRGPCQP--FCRAKEPVCGHNGETYSSVCAAYSDRVAVDYYGPCQAVGVLSEYSAVAECAAVKCPSLSAIGCKPIIPPGACCPLCAG-MLRVLFDKEKLDTIAKVTSKKP---ITVVEILQKVRMHVSVPQCDVFGYLSIESEIVILIIPVD--HYPKALQIEACNKEAEKIESLINSDSPTLASHVPLSALIISQVQVSSSLPSSAVVGR-PLFHSLLLLLSLGLTVHLLWTRP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95980-1", "uniprot_id": "RECK_HUMAN", "id": "O95980-1", "name": "Reversion-inducing cysteine-rich protein with Kazal motifs", "aln": "---------------------------------------------------------------------------MATVRASLRGALLLLLAVAGVAEVAGGLAPGSAGALCCNHSKDNQMCRDVCEQIFSSKSES-RLKHLLQRAPDYCPETMVEIWNCMNSSLP---------------------------GVFKKSDGWVGLGCCELAIALECRQACKQASSKNDISKVCRKEYENALFSCISRNEMGSVCCSYAGHHTNCREYCQAIFRTDSSPGPSQIKAVENYCASISPQLIHCVNNYTQSYPMRNPTDSLYCCDRAEDHACQNACKRILMSKKTEMEIVDGLIEGCKTQ----PLPQDPLWQCFLESSQSVHPGVTVHP-------------------PPSTGLDGAKLHCCSKANTSTCRELCTKLYSMSWGNTQSWQEFDRFCEYNPVEVSMLTCLADVREPCQLGCRNLTYCTNFNNRPTELFRSCNAQSDQGAMNDMKLWE-KGSIKMPFINIPVLDIKKCQPEMWKAIACSLQIKPCHSKSRGSIICKSDCVEILKKCGDQNKFPEDHTAESICELLSPTDDLKN---CIPLDTYLRPSTLGN-IVEEVTHPCNPNPCPANELCEVNRKGCPSGDPCLPYFCVQGCKLGEASDFIVRQGTLIQVP---------SSAGEVGCYKICSCGQSGLLENCMEMHCIDLQKSCIVGGKRKSHGTSFSIDCNVCSCFAGNLVCSTRLCLSEHSSEDDRRTFTGLPCNCADQFVPVCGQNGRTYPSACIARCVGLQDHQFEFGSCMSKDPCN---PNPCQKNQRCIPKPQVCLTTFDKFGCSQYECVPRQLA-CDQ-VQDPVCDTDHMEHNNLCTLYQRGKS--LSYKGPCQP--FCRATEPVCGHNGETYSSVCAAYSDRVAVDYYGDCQAVGVLSEHSSVAECASVKCPSLLAAGCKPIIPPGACCPLCAG-MLRVLFDKEKLDTIAKVTNKKP---ITVLEILQKIRMHVSVPQCDVFGYFSIESEIVILIIPVD--HYPKALQIEACNKEAEKIESLINSDSPTLASHVPLSALIISQVQVSSSVPSAGVRAR-PSCHSLLLPLSLGLALHLLWTYN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IKU3-1", "uniprot_id": "RECK_DANRE", "id": "A0A0R4IKU3-1", "name": "Reversion-inducing cysteine-rich protein with Kazal motifs", "aln": "-------------------------------------------------------------------------------MSGCLQILTVLLCCRFWALVFS-----QDQSCCVHHAADIPRCRDACEQLASIRSES-RLRHLLHRLPSYCPETLSELWICINNSLP---------------------------GASRKSDGWVGLGCCELAISAECRRDCKQASSKNDISKVCKKDTENPLYSCITKNEMGSVCCSYAGRHTTCREYCQAIFRTDSSPTVSQISAVKEYCQSVSPPLILCVENYTRLHPTHRPIDSLHCCDRAEEAHCQLACKRILRTLSTEQEIMDGLISECGSQ----PLPQDPLWQCFLG---SAHPPANTDPES-----------------PPIAKMDSAKLHCCFKANTSICRNMCVEIS-TSWG-TQSWQEFDQHCEYNPVEMDLITCLADVREPCQLGCKELSYCTNFNNRPTELFRSCNVQSDQGALNDFKLWS-NGSIRMPLMNIPVLDIRRCRPEMWKTVACALQIKPCYSRSRGSVICRSDCVEILRQCGDRRRFAEAQTPERICDLLSPTDDPER---CIPLNRYLTASELES-SVEEVIHPCNPNPCPSSHLCHVNRKGCHVGHDCLPYYCVPGCKLGEASEFLVPADARLQVP---------VHSAQPGCYEVCVCGQSGRLENCAEMPCFDTSKSCQIAGQRRSHGSSFRVDCNPCSCFAGDAVCSSRQCVRSDSSEEDRRLFTGLPCGCADHFVPVCAGNGRTYPSACVARCVGFTDSQFVFGSCRSFDPCS---PNPCQRNQRCVPRRQVCLTDLSEFPCPQYECVSRPSS-CDQKLLDPVCDTDNMEHANLCVLNLRGKT--LAYSGHCQD--ACRRPREVCAHNGESYSTVCEAFSERVAVDYQGRCHAVGLESEFGSDSGCNAVPCPPLASDACQPVTPPGACCPVCAG-MLRILWNKAQMNIFAKLNRDQP---VSLHDILKILRLHVSVPQCDIFGYLSINSEIIILIAPVD--QQPTPLQIEACSKEAEKIDSLINSGSPTLVSHVPLSAFLSSELQLSSVRSSSCVSIS---VCVLLLLCSLILTLTSDL---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VUJ2-1", "uniprot_id": "Q9VUJ2_DROME", "id": "Q9VUJ2-1", "name": "", "aln": "MRLSGWEILLFLLPFGVVSAVRQLEENQSIKNDHHHSVERQVRRRNNKSNASVDHHRHAPSSGSKKNSRSHSVSLDSDDYDWLDADTSEAIDSSEVTAVESIRSPGESYDIFTCCNQVFGSCRTACENLSLVEFATGTGGDNRDELHRYCQLHQVEFWTCVNQTFD----------------------------AITRGADWSGRRCCQFGVLPHCRNVCATSTRSP--VQNCRRSDEQTLYDCLERQEAADQCCGQA-RTSECLEACRAVFEPANDN--HDHVDINGACGDRNADVIQCVNNHTDMTPLANAEQYIPCCEYSSKEHCRHTCRNLLHQNATLMERSEVIFGRLEAAGCGSPLPQLPFWQCFLTVTGKLYVPGGSGRAGGSLAQGRISGQGGSLAEPNHLGMDAAKRQCCEQASSHKCRRLCNQIFTSNWWDARSS--FENECMDQPGERELRRCIESVDAPCELGCQGLSFCSNFNNRPTELFRSCTPEHDAAAREDWQLLQQRGTVRVLGQELFIKNTSRCAPDKWRALVCALQLKPCTRVGLFNGICSEDCHELLDECLDWT--LQHQRPKDICSRLKEKDDDDSPLPCISLESYLKPGDASPEEFQGITSPCAQKPCNGSEVCILQRGGNQG------YSCIPGCNLGQDSKLFVPFGSYVRLGKSNLHKKLEVGQFPLAEHIVCSCGLQGRLEQCQPLPSYMHAHCTLPGARSYRHGSSFYLECNLCSCFAGEITCTKQQCRLPGFVDSG---YTSLPCNCPAHYVPVCGSNGNTYPSACVAKCH-LPEGDYVYGACNARNACQAAPPNSCPSGTQCLDSRKVCLASMQRP-CLQYVCVNATASNCSTFHQGEVCDSQGRTYPNACALLKANPQGQVAYWSACQSSRFNTSPSPVCGINGVTYKSSYAARAEYVLVDYVGRCREVGLLVSDMG-RRCRTVKCPAPVSKHCRLIVPPGACCPLCAGGAFRIIYSRKQFDRAMYGLRAQSSTLLTLQGVLQQLDGLVQVSECQLTGFLTMEVGIFVAIVPSSSIKRPTHLQLEACAREAEKISSLINAQSPRITTNLALSCLTVSHLLEPTPNGATSYGPHAIWILPLLLLVSRVIIA-------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * . . ** .**:: . : . .. ** *:* *:*.:: . :. .* * **::.: .**. * :: . : *::. *:.*:.*: ::* .. **. * : : * * *:*:*.. .. : :: * . .. :* **:*:* * .. : : **: :.. *: :*:.:* * * : :: : **** *:***** . : * :*.** :** :*.: **.:* :: .* ::* *:. * :* * .: *: .* **:*** *::*:*************. : * .* .* :* . .*:::: .: : : * *: *:::.*:**:*** . . ** .** *:* :* * : : .: **. *. ** . **.*: ** .. .: : ** :** ...:* ::* * * *: **:**: *.::* .: ::: . : :* ** .* **:* : . :. ..: **:** ::** ******: .*:.: * :.. :*.***.*. ::****. **.******:*:* : : :: :*.* : :.*. ** * . :*: :***: :.. * ** ** : *. . ***:: : * *.* . ::* . ** **. ** :*.: * :: * *** * *: **: . . * :* **. : *: : *******:*** :*:::.: ::: :. ::: :*: : *.*.:*:: *::::: *.: * * . : *. **:*** :*****.****: ** :.:::.**.: *.: .: :: * * * : ", "identical_positions": 266, "similar_positions": 293, "identity": "23.6%" }, { "cls_id": "homologset.agr.RGD:1308846", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "B2RYC8-1", "uniprot_id": "B2RYC8_RAT", "id": "B2RYC8-1", "name": "Interleukin-1 receptor-associated kinase 3", "aln": "-----------------MAGPCGARGTLSPHSLLFDLPPALLGELCTILDSCDGPLGWRGLAERLSNSWLDVRHIEKYVHQGKSGTRELLWSWA-QKNKTIGDLLQVLHEMGHQRAIHLIMNYG-------------------VNWTPPVQTHHELRFPNLPPNSKPVCRESDPGPLELANVTVDNVLVPEHNERGVVLHKTPISFQSILEGTKHFHKDFLIGEGEIFEVYRVEIRNQTYAVKLFKQEKT--MQLKKHWKRFLSELEVLLLFNHPHILELAAYFTEMEKLCLVYPYMSNGTLFDRLQCTNGTTPLS---WHVRISVLIGIAKAIQCLHNTRPCAVICGNISSANILLDDQFQPKLTDFAAAHFRPHLEQQSSTINMTGSGRKHLWYMPEEYIRQGRLTIKTDVYSFGIVIMEVLTGCKVVLDDPKHVQLRDLLMELVEKRGLDSCLSFLDRKIPPCPRNFSAKLFSLAG--QCVATRAKLRPTMDEVLNTLESTQPSLYFAEDPPTSLKSFRCPSPLFLDNVPSIPVEDDENQNNYPVPPKEALRTDRVTQKTPFECSQSEVTFLGLDRNKGNRGSEAACNMPSSSCEECWCPELAEASQDLRPTVISLGSSWEVPGYSYGSKPMEKRCSSGLFCSEHEQSKRQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K4B2-1", "uniprot_id": "IRAK3_MOUSE", "id": "Q8K4B2-1", "name": "Interleukin-1 receptor-associated kinase 3", "aln": "-----------------MAGRCGARGALSPQLLLFDLPPALLGELCGILDSCDGPLGWRGLAERLSNSWLDVRHIEKYVNQGKSGTRELLWSWA-QKNKTIGDLLEVLQDMGHQRAIHLIINYG-------------------VSWTPSVQTHHELPFPSFPPEVKHACRENDPGPLEPANVTVDNVLVPEHNEKG-TLQKTPISFQSILEGTKHFHKDFLIGEGEIFEVYRVDIRNQAYAVKLFKQEKK--MQLKKHWKRFLSELEVLLLFRHPHILELAAYFTETEKLCLVYPYMSNGTLFDRLQCTNGTTPLS---WHVRISVLIGIAKAIQYLHNTQPCAVICGNVSSANILLDDQLQPKLTDFAAAHFRPNLEQQSSTINMTGGGRKHLWYMPEEYIRQGRLSVKTDVYSFGIVIMEVLTGCKVVLDDPKHVQLRDLLMELMEKRGLDSCLSFLDRKIPPCPRNFSAKLFSLAG--RCVATKAKLRPTMDEVLSSLESTQPSLYFAEDPPTSLKSFRCPSPLFLDNVPSIPVEDDENQNNHSVPPKEVLGTDRVTQKTPFECSQSEVTFLGLDRNRGNRGSEADCNVPSSSHEECWSPELVAPSQDLSPTVISLGSSWEVPGHSYGSKPMEKRCSSGLFCSEHEQSKKQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y616-1", "uniprot_id": "IRAK3_HUMAN", "id": "Q9Y616-1", "name": "Interleukin-1 receptor-associated kinase 3", "aln": "-----------------MAGNCGARGALSAHTLLFDLPPALLGELCAVLDSCDGALGWRGLAERLSSSWLDVRHIEKYVDQGKSGTRELLWSWA-QKNKTIGDLLQVLQEMGHRRAIHLITNYG-------------------AVLSPSEKSYQEGGFPNILFK-------------ETANVTVDNVLIPEHNEKG-ILLKSSISFQNIIEGTRNFHKDFLIGEGEIFEVYRVEIQNLTYAVKLFKQEKK--MQCKKHWKRFLSELEVLLLFHHPNILELAAYFTETEKFCLIYPYMRNGTLFDRLQCVGDTAPLP---WHIRIGILIGISKAIHYLHNVQPCSVICGSISSANILLDDQFQPKLTDFAMAHFRSHLEHQSCTINMTSSSSKHLWYMPEEYIRQGKLSIKTDVYSFGIVIMEVLTGCRVVLDDPKHIQLRDLLRELMEKRGLDSCLSFLDKKVPPCPRNFSAKLFCLAG--RCAATRAKLRPSMDEVLNTLESTQASLYFAEDPPTSLKSFRCPSPLFLENVPSIPVEDDESQNNNLLPSDEGLRIDRMTQKTPFECSQSEVMFLSLDKKPESKRNEEACNMPSSSCEESWFPKYIVPSQDLRPYKVNIDPSSEAPGHSCRSRPVESSCSSKFSWDEYEQYKKE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q05652-1", "uniprot_id": "KPEL_DROME", "id": "Q05652-1", "name": "Serine/threonine-protein kinase pelle", "aln": "MSGVQTAEAEAQAQNQANGNRTRSRSHLDNTMAIRLLPLPVRAQLCAHLDALD---VWQQLATAVKLYPDQVEQISSQKQRGRSASNEFLNIWGGQYNHTVQTLFALFKKLKLHNAMRLIKDYVSEDLHKYIPRSVPTISELRAAPDSSAKVNNGPPFPSSSGVSNSNNNRTSTTATEEIPSLESLGNIHISTVQRAAESLLEIDYAELENATDGWSPDNRLGQGGFGDVYRGKWKQLDVAIKVMNYRSPNIDQKMVELQQSYNELKYLNSIRHDNILALYGYSIKGGKPCLVYQLMKGGSLEARLRAHKAQNPLPALTWQQRFSISLGTARGIYFLHTARGTPLIHGDIKPANILLDQCLQPKIGDFGLVREGPKSLDAVVEVNKVFG---TKIYLPPEFRNFRQLSTGVDVYSFGIVLLEVFTGRQVTDRVPENETKKNLLDYVKQQWRQNRMELLEKHLAAPMGKELDMCMCAIEAGLHCTALDPQDRPSMNAVLKRFEPFVTD---------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. :*. *. : ** .: .:** **: * *: ** :. :*.:*.. .:*:*.:.*:* *. * *:*: *: :::.: :.*::** :* . .. : : **. * . : . : *.: .: :.* : * :*:* : :*** . :: *:*::: .. * . :: .**: * :.* :** * .* : * **:* * .*:* **:. **. *: *:.: :* ::.* **..: .:* *.:..******: :***: **. .: .: . :* . . *:* *: . :*: .********::**:** :*. *:: ::** : :: : : .: .* :::. : .: . :*.* .: **:*: **. :*. .. ", "identical_positions": 109, "similar_positions": 157, "identity": "16.67%" }, { "cls_id": "homologset.agr.RGD:1308847", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K1G4-1", "uniprot_id": "A0A0G2K1G4_RAT", "id": "A0A0G2K1G4-1", "name": "", "aln": "MIVFGWAVFLASRSLGQGLLLTLEEHIAHLLGTTGATTTMGNSCICRDDSGAEDSVDTHQQQAENSTVPTADSRSQLRDPVRPPRRGRGPHEPRRKKQNVDGLVLDTLAVIRTLVDNDQEPPYSMITLHEMAETDEGWLDVVQSLIRVIPLEDPLGPAVITLLLDECPLPTKDALQKLTEILNLNGEVACQDSGHPAKHRNTSAVLGCLAEKLAGPASIGLLSPGILEYLLQCLKLQSHPTVMLFALIALEKFAQTSENKLTISESSISDRLVTLELWADDPDYLKRQVGFCAQWSLDNLFLKEGRQLTYEKVDLNNIRAMLNSNDVSEYLKISPHGLEARCDASSFESVRCTFCVDTGVWYYEVTVVTSGVMQIGWATRDSKFLNHEGYGIGDDEYSCAYDGCRQLIWYNARSKPHVHPCWKEGDTVGFLLDLNEKQMIFFLNGNQLPPEKQVFSSTVSGFFAAASFMSYQQCEFNFGARPFKYPPSMKFSTFNDYAFLTAEEKIILPRHRRLALLKQVSIRENCCSLCCDEVADTQLKPCGHSDLCMDCALQLETCPLCRKEIVSRIRQISHIS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BVR6-1", "uniprot_id": "RSPRY_MOUSE", "id": "Q8BVR6-1", "name": "RING finger and SPRY domain-containing protein 1", "aln": "MIVFGWAVFLASRSLGQGLLLTLEEHIAHLLGTTGATATMGNSCICRDDSGAEDNVDTHQQQAENSTVPTADSRSQPRDPVRPPRRGRGPHEPRRKKQNVDGLVLDTLAVIRTLVDNDQEPPYSMITLHEMAETDEGWLDVVQSLIRVIPLEDPLGPAVITLLLDECPLPTKDALQKLTEILNLNGEVACQDSGHPAKHRNTSAVLGCLAEKLAGPASIGLLSPGILEYLLQCLKLQSHPTVMLFALIALEKFAQTSENKLTISESSISDRLVTLELWADDPDYLKRQVGFCAQWSLDNLFLKEGRQLTYEKVDLNNIRAMLNSNDVSEYLKISPHGLEARCDASSFESVRCTFCVDTGVWYYEVTVVTSGVMQIGWATRDSKFLNHEGYGIGDDEYSCAYDGCRQLIWYNARSKPHVHPCWKEGDTVGFLLDLNEKQMIFFLNGNQLPPEKQVFSSTVSGFFAAASFMSYQQCEFNFGARPFKYPPSMKFSTFNDYAFLTAEEKIILPRHRRLALLKQVSIRENCCSLCCDEVADTQLKPCGHSDLCMDCALQLETCPLCRKEIVSRIRQISHIS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96DX4-1", "uniprot_id": "RSPRY_HUMAN", "id": "Q96DX4-1", "name": "RING finger and SPRY domain-containing protein 1", "aln": "MIVFGWAVFLASRSLGQGLLLTLEEHIAHFLGTGGAATTMGNSCICRDDSGTDDSVDTQQQQAENSAVPTADTRSQPRDPVRPPRRGRGPHEPRRKKQNVDGLVLDTLAVIRTLVDNDQEPPYSMITLHEMAETDEGWLDVVQSLIRVIPLEDPLGPAVITLLLDECPLPTKDALQKLTEILNLNGEVACQDSSHPAKHRNTSAVLGCLAEKLAGPASIGLLSPGILEYLLQCLKLQSHPTVMLFALIALEKFAQTSENKLTISESSISDRLVTLESWANDPDYLKRQVGFCAQWSLDNLFLKEGRQLTYEKVNLSSIRAMLNSNDVSEYLKISPHGLEARCDASSFESVRCTFCVDAGVWYYEVTVVTSGVMQIGWATRDSKFLNHEGYGIGDDEYSCAYDGCRQLIWYNARSKPHIHPCWKEGDTVGFLLDLNEKQMIFFLNGNQLPPEKQVFSSTVSGFFAAASFMSYQQCEFNFGAKPFKYPPSMKFSTFNDYAFLTAEEKIILPRHRRLALLKQVSIRENCCSLCCDEVADTQLKPCGHSDLCMDCALQLETCPLCRKEIVSRIRQISHIS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****************************:*** **::*************::*.***:*******:*****:*** ********************************************************************************************************************.********************************************************************************** **:*********************************:*..****************************************:***********************************************************:**************************************************************:***********************************************************************************************", "identical_positions": 556, "similar_positions": 17, "identity": "96.53%" }, { "cls_id": "homologset.agr.RGD:1308848", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LEC1-1", "uniprot_id": "A0ABK0LEC1_RAT", "id": "A0ABK0LEC1-1", "name": "Prolyl 3-hydroxylase OGFOD1", "aln": "--MNGKRPADPGPARPMKKGKKQ------------------------VAAEFSDAVTEEILRKQVAEAWSCR----TPFSHEAIALDMDPFLHCVIPNFIQSQDFLEGLQKELLSLDFHEKYNDLYKFQQSDDLKKRKEP-HISALRTLMFEDFRAWLSKVSGIDLEATVDMSCAKYEFTDALLCHDDELEGRRIAFILYLVP-----SWDRDLGGTLDLYDTDEHLQPKQ-IVKSLVPAWNKLVFFEVSP-VSFHQVSEVLSEELTRLSISGWFHGPSLAR-----------------PPTYFEPPVPRSPHIPQD-----------------------------------------------HEILYEWINPAYLEMDYQMQIQEEFEERSEILLKEFLKPEKFAKVCEALEKG-------------DVEWKSHGPPNKRFYEKAKESNLP--DVLKECMGLFHSEAMFLLLSNFTGLKLHFLAPSEDDETEDKGEG---------ETASAAGGTEEGTSQSPPGPEDNQAAVGSHSQENGEQADPEPQEDEAKKESSVPMCQGELRRWKTGHYTLVHDNSKTEFALDLFLYCGCEGWEPEYGGFTSYIAKGEDEELLIVNPENNALALVYRDRETLRFVKHIN----HRSLEQRNTFPNRSGFWDFAFMYYE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3U0K8-1", "uniprot_id": "OGFD1_MOUSE", "id": "Q3U0K8-1", "name": "Prolyl 3-hydroxylase OGFOD1", "aln": "--MNGKRPADPGPARPMKKGKKQ------------------------VSAEFSDAVTEEILRKQVAEAWSCR----TPFSHEAIALDMDPFLHCVIPNFIQSQDFLEGLHKELLSLDFHEKYNDLYKFQQSDDLKNRKEP-HISALRKLMFEDFRAWLSKVSGIDLEPTIDMSCAKYEFTDALLCHDDELEGRRIAFILYLVP-----SWDRDLGGTLDLYDTDEHLQPKQ-IVKSLIPSWNKLVFFEVSP-VSFHQVSEVLSEETSRLSISGWFYGPSLTR-----------------PPTYFEPPIPRNPHIPQD-----------------------------------------------HEILYEWINPAYLEMDYQMQIQEEFEERSEILLKEFLKPEKFAEVCEALEKG-------------DVEWKSHGPPNKRFYEKAEENNLP--DVLKECMGLFRSEALFLLLSNLTGLKLHFLAPSEDDETEEKGEG---------ETASAAAGTEEGTSRRPSGPENNQVAAGSHSQENGEQADPEAQEEEAKKESSVPMCQGELRRWKTGHYTLVHDNTKTEFALDLFLYCGCEGWEPEYGGFTSYIAKGEDEELLIVNPENNSLALVYRDRETLRFVKHIN----HRSLEQSKAFPSRSGFWDFAFIYYE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N543-1", "uniprot_id": "OGFD1_HUMAN", "id": "Q8N543-1", "name": "Prolyl 3-hydroxylase OGFOD1", "aln": "--MNGKRPAEPGPARVGKKGKKE------------------------VMAEFSDAVTEETLKKQVAEAWSRR----TPFSHEVIVMDMDPFLHCVIPNFIQSQDFLEGLQKELMNLDFHEKYNDLYKFQQSDDLKKRREP-HISTLRKILFEDFRSWLSDISKIDLESTIDMSCAKYEFTDALLCHDDELEGRRIAFILYLVP-----PWDRSMGGTLDLYSIDEHFQPKQ-IVKSLIPSWNKLVFFEVSP-VSFHQVSEVLSEEKSRLSISGWFHGPSLTR-----------------PPNYFEPPIPRSPHIPQD-----------------------------------------------HEILYDWINPTYLDMDYQVQIQEEFEESSEILLKEFLKPEKFTKVCEALEHG-------------HVEWSSRGPPNKRFYEKAEESKLP--EILKECMKLFRSEALFLLLSNFTGLKLHFLAPSEEDEMNDKKEA---------ETT---DITEEGTSHSPPEPENNQMAISNNSQQSNEQTDPEPEENETKKESSVPMCQGELRHWKTGHYTLIHDHSKAEFALDLILYCGCEGWEPEYGGFTSYIAKGEDEELLTVNPESNSLALVYRDRETLKFVKHIN----HRSLEQKKTFPNRTGFWDFSFIYYE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9I7H9-1", "uniprot_id": "OGFD1_DROME", "id": "Q9I7H9-1", "name": "Prolyl 3-hydroxylase sudestada1", "aln": "METSSSSPVKPRRKDKDEDGRAEQEDSADQVGEPHRKLLRLGDILETNEVLLNEAYQQPELTKWLQTAWTEEKSQGTKETQTGAQVFSDPFQICLLPGMLEKGQSQALVAEIIQKVQWSRKQMDLYEFYQSADLSNMPACRLLTNFLQVLRKQVRPWLEKVTNLKLD-YVSASCSMYTCGDYLLVHDDLLKDRQVAFIYYLSPWEGAEEWTDEQGGCLEIFGSDDQCFPQFPVQRKIAPKDNQFAFFKVGS-RSFHQVGEVTTFDYPRLTINGWFHGDTNEA-----------------FVADSLRAFPRLNYLQPDG--------------------------------------------LNRPPLGLFLNNVYLKGATRRSIQKRIEENSEICLYEFFKREKFELARSQLLADS-----------DTLKWRRQGPANAHNYEVLDLTTAR--GTILELLQLFRSHAMFDLLRDFTDLD---LAGTDAESPTCSVEL---------QRWSHGNYTVLGDGLTSEENTLDLVYYLNAAEGAAVITYLAPDAEMPTAKAPT------------------------------------DGRRSDYD-----DEEEDDSVLLTITPVDNALNIVYRCEGTTKFTKYVSR---NTPLEKGPVFVISCSYKE-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40032-1", "uniprot_id": "TPA1_YEAST", "id": "P40032-1", "name": "Prolyl 3,4-dihydroxylase TPA1", "aln": "--MKRKTAEVKGEKERNSKQISLE------------------------EDKIKGMFNPKIWDKTFQDGLKKEIEDSQPYNWGTIHELVNDDLLRAVRKEIETEIHFTKKETDIYRVNQSGDLANLSGLDWDDLSRLPNLFKLRQILYSKQYRDFFGYVTKAGKLSGS-KTDMSINTYTKGCHLLTHDDVIGSRRISFILYLPDPD--RKWKSHYGGGLRLFPSILPNVPHSDPSAKLVPQFNQIAFFKVLPGFSFHDVEEVK-VDKHRLSIQGWYHIPQVGEEGYIPGEEEAWVRNNTSTLAQIESNVLEDFEFPKDERNILSFHEVKHFEKMLKGDAGAKTDNTPKESMTSVISDSVKLSEAEFTYLSQYISPEHLSSKGIEKLQKQFVENSSLQIESFLNDDKSELLKKVIKQKELEQECPYHSKDVKAPWKTAIPPHKARYLYIDGKEYRNFQTEADILEALNNNDLPNFQFTKDAIKIISDASGNSRENNFDAELALIDLAVFHKSTIFKKYLALLTSLCPVSEQILIRRFRPGMDFTLATKCRFNELLKSNPDIIDAVLEGTLCLTPSAGWESGELGGYELYMMDDDEDNKQYLKEDVEDASVYRADDSGDSVLINDPPAWNTFNLVLRDESVLEFVKYVSWSAKSSRWDVKMKWDVKSCDEDGQEDEA-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . .. :. * . . . . . : : ::. : :: . :* : . : .:. :: . :. . . * * ** *** : .*:::** ** * ** * :: *: .: * *::.**:* . ***:* ** : **:*.**:: . . : * * ::. :*. .:*:.: * *.: : .*:: :* . : * *.: * . . : : :... : : :. * : . . * : . . : : .. . . . . *. *: * *:: :* * . . .*.*::. : : : ", "identical_positions": 56, "similar_positions": 121, "identity": "8.3%" }, { "cls_id": "homologset.agr.RGD:1308849", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q92781-1", "uniprot_id": "RDH5_HUMAN", "id": "Q92781-1", "name": "Retinol dehydrogenase 5", "aln": "MWLPLLLGALLWAVLWLLRDRQSLPASNAFVFITGCDSGFGRLLALQLDQRGFRVLASCLTPSGAEDLQR-VASSRLHTTLLDITDPQSVQQAAKWVEMHVKEAGLFGLVNNAGVAGIIGPTPWLTRDDFQRVLNVNTMGPIGVTLALLPLLQQARGRVINITSVLGRLAANGGGYCVSKFGLEAFSDSLRRDVAHFGIRVSIVEPGFFRTPVTNLESLEKTLQACWARLPPATQAHYGGAFLTKYLKMQQRIMNLICDPDLTKVSRCLEHALTARHPRTRYSPGWDAKLLWLPASYLPASLVDAVLTWVLPKPAQAVY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZKU7-1", "uniprot_id": "BL1S1_RAT", "id": "D3ZKU7-1", "name": "Biogenesis of lysosome-related organelles complex 1 subunit 1", "aln": "-----MLSRLLKEHQAKQNERKELQEK---------------------RRREAITAATCLTEALVDHLNVGVAQAYMNQRKLDHEVKTLQVQAAQFAKQTGQWIGMVENFN-------------------------QALKEIG--------------------------------------DVENWARSIELDMRTIATALEYVYKGQLQSAPS---------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*. ** .:*:.* . :* . *:*** : .:.*: **.: :: ** ***::.: : *:. .* ::: ** .:* :: *:. *: :. :. * * :::. : ", "identical_positions": 27, "similar_positions": 46, "identity": "8.46%" }, { "cls_id": "homologset.agr.RGD:1308850", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4A2U6-1", "uniprot_id": "D4A2U6_RAT", "id": "D4A2U6-1", "name": "", "aln": "---MKLQVFWTG----------------LEYTCRLLGITTAAVLIGVGTETFLRGRFKSLAFYLLFTGVTISVCEGTYFVAQLLAICFKCQ----PGSLAHRAKEKAHWLGCFQKFLAYMLLSVACFLHPVLVWHVTIPGSMLIITGLAYFLLSKRKKKKAAPEVMPPTEQYRDPSSSIVSTTGSGDTEQTYTFHEAFKEGPSSFLIH----------MKSILKGTKKPRVLQAQDTLMELALEPADSLAKK-KQVHFEDNVVRIIPSLTEG---LGDSDSGPEETSSDTTPIIPPSQTP-LFLPS-----------LMATDLF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C3K5-1", "uniprot_id": "TMM72_MOUSE", "id": "Q8C3K5-1", "name": "Transmembrane protein 72", "aln": "---MKLQVFWTG----------------LEYTCRLLGIATAAVLIGVGTETFLRGRFKSLAFYLLFTGVTISVCEGTYFVAQLLAICFKCQ----PGSLAHRAKERAHWLGCFQKFLAYMLLSVACFLHPVLVWHVTIPGSMLIITGLAYFLLSKRKKKKAAPEVAPPTEQYTDPSSSVVSTTGSGDTEQTYTFHEAFKEGPGSFFIH----------MKSILKGTKKPRVLQTQDTLMELALEPADSLAKK-KQVHFEDNVVRIIPSLTEG---LGDSDSEPEETSSDTTPIIPPSQTP-HFLPS-----------LMATDLF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0PK05-1", "uniprot_id": "TMM72_HUMAN", "id": "A0PK05-1", "name": "Transmembrane protein 72", "aln": "---MQLQVFWTG----------------LEYTCRLLGITTAAVLIGVGTETFLQGQFKSLAFYLLFTGAAVSICEGAYFVAQLLAICFQCQ----PGSLADRVREKAHWLGCFQKFLAYLLLSVACFLHPVLVWHVTIPGSMLIITGLAYFLLSKRKKRKAAPEVLASPEQYTDPSSSAVSTTGSGDTEQTYTFHGALKEGPSSLFIH----------MKSILKGTKKPSALQPPNTLMELSLEPADSLAKK-KQVHFEDNLVRIVPSLAEG---LDDGDSEPEETTSDTTPIIPPPQAP-LFLSS-----------LTATGLF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P9W7-1", "uniprot_id": "A0A8M1P9W7_DANRE", "id": "A0A8M1P9W7-1", "name": "", "aln": "---MKGSALWVI----------------VECSCRVLGISTAAVLCAVGIETQSQGEFTSLAVYLLLSSLVIMIFEVAYFIDALLATCLPCP----PTWKMFILWKKMAKVGGFQKFLYYTMMSVMCFLHPVLVWHAVIPGIMLVVTGFFNFILSKKKKSDVPKE---SRVFYGDPALSSVCVKDRGDSEDTFSFFNVISGKRASFIPNNSRIHDLTDRDQSLKNGQHKKRQTDRRNVHFIKSLRSNDTEMEEYHEVESEETTSDKAPMITLVSCWKKKENCFLFQSVTLSLGLLHPSIHPSIRLHTSIQLRDSIHHLLTQTRRF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VVY1-1", "uniprot_id": "Q9VVY1_DROME", "id": "Q9VVY1-1", "name": "Transmembrane protein 72", "aln": "MSQMQLQSQRVRRARHHRRNQSAEPCECLRPVIRVFGLLTSFVICGVGVDVYMHG--YRAGLYIVFSAVLVMFIEIKWLVTIFLQLQCAEDNYQRRSCSCLACWRLSAICGGWRPTPVYAVIGICLILYPHNLWLSYVAGMFLILLGLLRLCTLLRFS-----------------ASKEEGLLPQCDFEKVSSFVDTMEDDFAEIGAT-------------------------------QAGLDEEAEEEGD-DHTALDDDVC-------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: . . :. *::*: *: *: .** :. :* ..*::::. : . * ::: :* . * :: * ::.: :*:* :* :.* :*:: *: : : . : . * *.. :* .:. ..: .* . ... :: ", "identical_positions": 23, "similar_positions": 64, "identity": "7.1%" }, { "cls_id": "homologset.agr.RGD:1308851", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8J8XIM5-1", "uniprot_id": "A0A8J8XIM5_RAT", "id": "A0A8J8XIM5-1", "name": "Glyoxylate reductase/hydroxypyruvate reductase", "aln": "----ARLVNVCSCGSCETRATHEGVRHW-PFAGPGQGCARPGHRVSARVGVGSAAEPLARCPVHPTSDTPAAALGRSCEVEQWNSDDPIPSKDLEQGVAGAYGLLCRLSDRVDKKLLDAAGANLRVISTLSVGVDHLALDEIKKRGIRVGYTPGVLTDATAELAVSLLLTTCRRLPEAIEEVKNGGWSSWSPLW--MCGYGLSESTVGIVGLGRIGQAIARRLKPFGVQRFLYTGRQPRP-QEAAEFQAEFVPIAQLAAESDFIVVSCSLTPATRGLCNKDFFQKMKNTAVFINISRGDVVNQEDLYQALASGQIAAAGLDVTTPEPLPPSHPLLTLKNCVILPHIGSATYKTRNTMSLLAAN------------NLLAGLRGEPMPSELKL--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91Z53-1", "uniprot_id": "GRHPR_MOUSE", "id": "Q91Z53-1", "name": "Glyoxylate reductase/hydroxypyruvate reductase", "aln": "-MKPARLMKVFVTG---------------PLPAEG------------RAALAQAAD---------------------CEVEQWNSDDPIPRKDLEQGVVGAHGLLCRLSDRVDKKLLDAAGANLRVISTLSVGVDHLALDEIKKRGIRVGYTPGVLTDATAELAVSLLLTTCRRLPEAIEEVKNGGWSSWSPLW--MCGYGLSQSTVGIVGLGRIGQAIARRLKPFGVQRFLYTGRQPRP-QEAAEFQAEFVPIAQLAAESDFIVVSCSLTPDTMGLCSKDFFQKMKNTAIFINISRGDVVNQEDLYQALASGQIAAAGLDVTTPEPLPPSHPLLTLKNCVILPHIGSATYKTRNTMSLLAAN------------NLLAGLRGEAMPSELKL--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UBQ7-1", "uniprot_id": "GRHPR_HUMAN", "id": "Q9UBQ7-1", "name": "Glyoxylate reductase/hydroxypyruvate reductase", "aln": "-MRPVRLMKVFVTR---------------RIPAEG------------RVALARAAD---------------------CEVEQWDSDEPIPAKELERGVAGAHGLLCLLSDHVDKRILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRLPEAIEEVKNGGWTSWKPLW--LCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRP-EEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGSATHRTRNTMSLLAAN------------NLLAGLRGEPMPSELKL--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8I725-1", "uniprot_id": "Q8I725_DROME", "id": "Q8I725-1", "name": "Glyoxylate reductase/hydroxypyruvate reductase", "aln": "--MPPRLPFGQVRN----------------LLIQGHIIRRMSSQHKVYVTRPDVDD------------SGLELLRKSCQVSTWHETNPVPRSELIRVVAGKDALYCALTDKVDKEVLDAAGPQLKCVATISVGYDHIDVEECRKRGIRVGFTPDVLTDATAELTLALLLATNRRLFEANKQVYNGGWKSWAPMW--MCGQGLKGSRVGLLGFGRIGQEIAARIVPFKPTEITYTTRSLRP-KEAAAVNARHVDFDEMLRESDLIVVCCALTPETKEIFNATAFQKMKPNCILINTARGGVVDQKALYEALKTKRILAAGLDVTTPEPLPIDDPLLKLDNVVILPHIGSADIETRKEMSRITAR------------NILAALAGDKMVAEVEL--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VII9-1", "uniprot_id": "Q9VII9_DROME", "id": "Q9VII9-1", "name": "Glyoxylate reductase/hydroxypyruvate reductase", "aln": "MSRATRAFKVLISHP--------------NVPAPA-------------LELLRSRG----------------------AETIICQSVPPSRDEILQKVPGVDAIYWAHYQPLNAGILDAAGSQLRCVSTMSSGIDFVDIPEFQKRGIPLGHTPGVVKNAVADLAIGLMIAAGRHFHAGRTEIERSQWKIEQINW--MMGQEIRDSVIGFFGFGGISQAIAKRLQCWDVAKIIYHTRTRK--ENDGDFKAEHVSFEQLLQESDFLVVAAPLTNETREKFNGKAFNLMKRSSVFVNVARGGLVNQTDLHDALTNGTISAAGLDVTTPEPLPANSPLLNVPNCVILPHMGTQTMKTTIEMGLLAAN------------NILNAIEGKPMIRPAY---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8INU6-1", "uniprot_id": "Q8INU6_DROME", "id": "Q8INU6-1", "name": "Glyoxylate reductase/hydroxypyruvate reductase", "aln": "MS-TTKPFKVLIAHT--------------DVPPEG-------------IEILKEQC----------------------EILQVINEPPKNRPEILEKIRGAHAVIWGGRDILNAEILDAAGPQLKAVSTMSSGINNVDVPELKKRGIPLGSTPAMLTVAVADLTVGLLIAAARRFQEGRRKIDSDKWDKDHLNW--MLGQDIRDSTVGFYGFGGIGQAVAKRLMGFDIKRMLYTTRNRVSQDIEERFNAKKVDFETLLAESDFLIIASPLTKETLGLFNATVFNKMKETAVLVNVGRGKIVNQDDLYEALKSNRIFAAGLDVMDPEPLPSNDKLLTLDNVVVTPHVGYATRRTRVDAANLASR------------NVLKGLAGEPMLSPAY---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53839-1", "uniprot_id": "GOR1_YEAST", "id": "P53839-1", "name": "Glyoxylate reductase 1", "aln": "MSKKPIVLKLGKDAFG--------DQAWG-----------ELEKIADVITIPESTT----------------------REQFLREVKDPQNKLSQVQVITRTARSVKNTGRFDEELALALPSSVVAVCHTGAGYDQIDVEPFKKRHIQVANVPDLVSNATADTHVFLLLGALRNFGIGNRRLIEGNWPEAGPACGSPFGYDPEGKTVGILGLGRIGRCILERLKPFGFENFIYHNRHQLP--SEEEHGCEYVGFEEFLKRSDIVSVNVPLNHNTHHLINAETIEKMKDGVVIVNTARGAVIDEQAMTDALRSGKIRSAGLDVFEYEPK-ISKELLSMSQVLGLPHMGTHSVETRKKMEELVVENAKNVILTGKVLTIVPELQNEDWPNESKPLV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . .: : * ..: :. . * : : : :** * :. .* ::. :.*: : *:: : *.: . .: . * * . :*: *:* *.: : *: : .: * * .. * : .**:: : .*. * . :: ** :::* .** :::: : :** . * :***** ** . **.: : : **:* .* :. . .:: : .. ", "identical_positions": 44, "similar_positions": 86, "identity": "11.17%" }, { "cls_id": "homologset.agr.RGD:1308852", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q91W36-1", "uniprot_id": "UBP3_MOUSE", "id": "Q91W36-1", "name": "Ubiquitin carboxyl-terminal hydrolase 3", "aln": "MECPHLSSSVCIAPDSAKFPNGSPSSWCCSVCRSNKSPWVCLTCSSVHCGRYVNGHAKKHYEDAQIPLLNHKRSEKQEKAQHTVCMDCSSYSTYCYRCDDFVVNDTKLGLVQKVREHLQNLENSAFTADRHRKRKLLENSSLNSKLLKVNGSTTAICATGLRNLGNTCFMNAILQSLSNIEQFCCYFKELPAVELRNGKTAGRRTYHTRSQGDSNVSLVEEFRKTLCALWQGSQTAFSPESLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLHLELQGGFNGVSRSAILQENSTLSASNKCCINGASTVVTAIFGGILQNEVNCLICGTESRKFDPFLDLSLDIPSQFRSKRSKNQENGPVCSLRDCLRSFTDLEELDETELYMCHKCKKKQKSTKKFWIQKLPKALCLHLKRFHWTAYLRNKVDTYVQFPLRGLDMKCYLLEPENSGPDSCLYDLAAVVVHHGSGVGSGHYTAYAVHEGRWFHFNDSTVTVTDEETVGKAKAYILFYVERQARAGAEKL----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y6I4-1", "uniprot_id": "UBP3_HUMAN", "id": "Q9Y6I4-1", "name": "Ubiquitin carboxyl-terminal hydrolase 3", "aln": "MECPHLSSSVCIAPDSAKFPNGSPSSWCCSVCRSNKSPWVCLTCSSVHCGRYVNGHAKKHYEDAQVPLTNHKKSEKQDKVQHTVCMDCSSYSTYCYRCDDFVVNDTKLGLVQKVREHLQNLENSAFTADRHKKRKLLENSTLNSKLLKVNGSTTAICATGLRNLGNTCFMNAILQSLSNIEQFCCYFKELPAVELRNGKTAGRRTYHTRSQGDNNVSLVEEFRKTLCALWQGSQTAFSPESLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLHLELQGGFNGVSRSAILQENSTLSASNKCCINGASTVVTAIFGGILQNEVNCLICGTESRKFDPFLDLSLDIPSQFRSKRSKNQENGPVCSLRDCLRSFTDLEELDETELYMCHKCKKKQKSTKKFWIQKLPKVLCLHLKRFHWTAYLRNKVDTYVEFPLRGLDMKCYLLEPENSGPESCLYDLAAVVVHHGSGVGSGHYTAYATHEGRWFHFNDSTVTLTDEETVVKAKAYILFYVEHQAKAGSDKL----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0M1L0-1", "uniprot_id": "A0ABK0M1L0_RAT", "id": "A0ABK0M1L0-1", "name": "Ubiquitin carboxyl-terminal hydrolase 3", "aln": "MECPHLSSSVCIAPDSAKFPNGSPSSWCCSVCRSNKSPWVCLTCSSVHCGRYVNGHAKKHYEDAQIPLLNHKRSEKQEKAQHTVCMDCSSYSTYCYRCDDFVVNDTKLGLVQKVREHLQNLENSAFTADRHRKRKLLENSSLNSKLLKVNGSTAAICATGLRNLGNTCFMNAILQSLSNIEQFCCYFKELPAVELRNGKTAGRRTYHTRSQGDSNVSLVEEFRKTLCALWQGSQTAFSPESLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLHLELQGGFNGVSRSAILQENSTLSANNKCCINGASTVVTTIFGGILQNEVNCLICGTESRKFDPFLDLSLDIPSQFRSKRSKNQENGPVCSLRDCLRSFTDLEELDETELYMCHKCKKKQKSTKKFWIQKLPKALCLHLKRFHWTAYLRNKVDTYVQFPLRGLDMKCYLLEPENSGPDSCLYDLAAVVVHHGSGLIKKLFYFQTWTSILGPAITHISVLLSLQTWFDQLVIAGWFWALHSICSSRRPLVPFQ", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****************************************************************:** ***:****:*.***************************************************:********:************:***********************************************************.***********************************************************************************.*************:*********************************************************************************************.**********************:********************:****************: . : : . :.. :* :: : . : *:. :. :. * ", "identical_positions": 455, "similar_positions": 33, "identity": "86.83%" }, { "cls_id": "homologset.agr.RGD:1308853", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "F7FCJ4-1", "uniprot_id": "F7FCJ4_RAT", "id": "F7FCJ4-1", "name": "", "aln": "-----------------------------------------------MAKFVLNQNLPDLGGPSLYPGPTG-SARSPSSPYSVETPYGFHLDLDFLKYVEEIERGPASRRAPGPPHARRPRASGKGLAGAR--SPGAWTSSE------SLASDDGGASGALSPGAFPGLSLPPLSPRSFSRNPR-------------------------------------------------------------VEHTLLETSRRLEQAQAQER----------------------------------------------------------------------------------------------------------ALSPARAATRSPR---------------------GSGRSSPAPNPALASPSPVLASPGPAQLQLVREQMAVALRRLRELEDQARALPELQEQVRALRAEKARLLAG--------RVQPEQDVEIEVRPDKLSQLRRLTERLATSDRGVRSRASPRAEDPDGLAARRSEGALQVLDPASR--------------------------------------------------------------------TPDGEPQTREAGTEVVPETREVDAQAVPETREAG----------------------------------------------------VEVVPETVEVDTWVTEALLGLPEAAERELELLRTSLEHQRGVSELLRGRLRELEEAHEAIVT-----RSQSREVATQTTLGYTEKTTQTELPVES---------------------------------------------------------------------------------------------------------QPRPTAGD-EMAPAGILKSIMKKKDGTPGAQSSQ-GPKSLQFVG---------VLNGEYESSSSEDASNSDDE-DDVAELPRSSSSGSGDDSSGGSDAGTPGPHN----------------------------------DQDAGDCELEMHPEQKTGREGRCELNPRLREACIALNQQLMRPRGVTSRDALMPTLSWSCQNAARLVAQEWFRVSSQKRCQAEPVAGVLRGVKSLGPELLAHVVNLADGNGNTALHYSVSHGNLAISSLLLDTGVCDVNHQNRAGYSALMLAALTSVGKEEEDMAVVQRLFSMGDVNAKASQTGQTALMLAISHGHQDMVAALLECGADVNVQDADGATALMCASEYGRLDTVQLLLAQPGCDLTILDNEGTSALAIALEAEQDEVAALLHAHLTSNHHDSQEQSTPGSPTAT----LQRDTGPQPL--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z1P7-1", "uniprot_id": "KANK3_MOUSE", "id": "Q9Z1P7-1", "name": "KN motif and ankyrin repeat domain-containing protein 3", "aln": "-----------------------------------------------MAKFVLNQNLPDLGGPPLYPGPTG-SARSPSSPYSVETPYGFHLDLDFLKYVEEIERGPASRRTPGPPHARRPRASRTGLAGAR--SPGAWTSSE------SLASDDGGASGALSPGAFPGLSLPPLSPRSLSRNPR-------------------------------------------------------------VEHTLLETSRRLEQAQARER----------------------------------------------------------------------------------------------------------ALSPARAVTRSPR---------------------GSGRSSPAPNPALASP-------GPAQLQLVREQMAAALRRLRELEDQARALPELQEQVRALRAEKARLLAG--------RVQPEQEVEIEARPDKLAQLRRLTERLATSDRGVRSRASPRAEDPDGLAARRSEGALQVLDPGSR--------------------------------------------------------------------TPDGEPRTRETGTEVVPETREVDAQAVPETGEAG----------------------------------------------------VEVVPETVEVDTWVTEELLGLPEAAERELELLRTSLEHQRGVSELLRGRLRELEEAHEAAVT-----RPQSRDVAAQTTLGCTEKTTQTELPVEN---------------------------------------------------------------------------------------------------------QPRPTAGD-EMAPVGILKSIMKKKDGIPGAQSSQ-GPKSLQFVG---------VLNGEYESSSSEDG-NSDDE-DGVAEHPRSSSSGS-DDSSGGSDAGTPGPHN----------------------------------DKDAGDCELETHPELTAGREGRCELNPRLREACIALNQQLNRPRGVTSRDG----------NAARLVAQEWFRVSSQKRSQAESVAGVLRGVKSLGPELLAYVVNLADGNGNTALHYSVSHGNLAISSLLLDTGVCDVNHQNRAGYSALMLAALTSVGQEEEDMAVAQRLFSMGDVNAKASQTGQTALMLAISHGHQDMVAALLECGADVNVQDADGATALMCASEYGRLDTVQLLLAQPGCDLTILDNEGTSALAIALEAEQDEVAALLHAHLTSNHQG---QSSTGSPTAK----ECNDK-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6NY19-2", "uniprot_id": "KANK3_HUMAN", "id": "Q6NY19-2", "name": "KN motif and ankyrin repeat domain-containing protein 3", "aln": "-----------------------------------------------MAKFALNQNLPDLGGPRLCPVPAAGGARSPSSPYSVETPYGFHLDLDFLKYIEELERGPAARRAPGPPTSRRPRAPRPGLAGAR--SPGAWTSSE------SLASDDGGAPGILSQGAPSGLLMQPLSPRAPVRNPR-------------------------------------------------------------VEHTLRETSRRLELAQTHER----------------------------------------------------------------------------------------------------------APSPGRGVPRSPR---------------------GSGRSSPAPNLAPASP-------GPAQLQLVREQMAAALRRLRELEDQARTLPELQEQVRALRAEKARLLAG--------RAQPEPDGEAETRPDKLAQLRRLTERLATSERGGRARASPRADSPDGLAAGRSEGALQVLDGEVG--------------------------------------------------------------------SLDGTPQTREVAAEAVPETREAGAQAVPETREAG----------------------------------------------------VEAAPETVEADAWVTEALLGLPAAAERELELLRASLEHQRGVSELLRGRLRELEEAREAAEEAAAGARAQLREATTQTPWSCAEKAAQTESPAEAPSLTQE--------------------------------------------------------------------------------------------------SSPGSMDGDRAVAPAGILKSIMKKRDGTPGAQPSS-GPKSLQFVG---------VLNGEYESSSSEDASDSDGDSENGGAEPPGSSSGSGDDSGGGSDSGTPGPPS----------------------------------GGDIRDPEPEAEAEPQQVAQGRCELSPRLREACVALQRQLSRPRGVASDGG-----------AVRLVAQEWFRVSSQRRSQAEPVARMLEGVRRLGPELLAHVVNLADGNGNTALHYSVSHGNLAIASLLLDTGACEVNRQNRAGYSALMLAALTSVRQEEEDMAVVQRLFCMGDVNAKASQTGQTALMLAISHGRQDMVATLLACGADVNAQDADGATALMCASEYGRLDTVRLLLTQPGCDPAILDNEGTSALAIALEAEQDEVAALLHAHLSSGQPDTQSESPPGSQTATPGEGECGDNGENPQVQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8DYE0-1", "uniprot_id": "A8DYE0_DROME", "id": "A8DYE0-1", "name": "", "aln": "MSVRPNNAGDMLLHNSVIGGYDESKFAEKITHLTPTEQEAVKRFWRSLVLRSQRAFIEENARPIASSANPAPAGITRSVRSCNCCPYGYHIDLDFVRYCEALALEKPSEEEQRRRDRRRSRKSMEFMLGFESLFGGDWQAESRVQGKLSETSHESEPDSPHPIGGGGSLHMSQSYTTTPCYRPRSSSVPRFTYGSIPPRSESPFGTASSTCSSLRGGVESDAGIYHQRHRPAISPPETRAFLHEALDEVCSDFERTLERTSVKRRKSPYGAGSLSMDRNNNKLSLSISNGHGALKELKSHRLGNSTWDRHFDVADSCIGGNQSPTGTPRPFLRSNTLPLRQRPSPAEVQYESYVQATVAANAKSPVEQLESAKSPGAPPPPPPRRHHLLATTPTGKPTFKEDRPQENGSVSSSSLQSPVISETGQTTADAQALFQIREQMALSLRRLKDLEEQVKVIPDMELELNSLRSEKQKLLRRNEELMRSQRQTPSPPSPGLKTASPVQFTPQRISPVSLESLGARMRSSSTSASPSPSVVRRDVSTQAVVRPPATRDVSVGHQPTTRNVGVQPSETVYSKEELDKKVEQALTNAQKQQLRKLISVGTQMYVPQRDQKDSGVQTTPERPKLKYHVGVTVKPATRENFTSCKPDVRHVGSSDDRLDDVLCEKCAVSKRSVACGPETPAEKVKPAPQMPGRSNTFSLGENETVSVVRKTIGCQTPVTLVLSSGSQTTTAVVRSTGAQVNPQQQHSGVQCATEQVSRQTDTKGLQRLTRSQTKAEQVSESVPRPTTRHTASNTDKVEEAEPAKVRTSHSACNTEEVRKRDVGCGDIVKPHISIACAANYCDSCKEAIQDLARGFSKASPTATRTGGAVRRSTSADSRIPRPKHLSSPSPVRKEFMRQNTYTLATPSPTPSP-QVERKARLSSLQEKPPSVSSFQASEPLPESQSFIRQPQKDSLDLSLLGEDELIVREEKRVSISWSRDASPAPLMTSSGTTKSESPEQEPAMSSSSDSSPPIDVQIAQGARKKSSTPLKSSQSEGSQVTVIEQPATKAQLHQLAQADSEPRKKTELSQSLKDALKIINDSLLKKLGAKPISSQ------SLKSAKATIQDHWFTNSSTGKSDPHQVEDYLDYFESLSIPLLEYCVNLSDSNGNTAMHYAVSHGNFDVVSILLDSKVCDVNQMNNAGYTSVMLVSLAKLKQP-AHRTVVERLFKMADVNIRAKKHCQTALMLAVSHGNGDMVNMLLDAGADINIQDEDGSTALMCAAEHGRVDVIKHLLSHPECDSLVTDVDGSTAFKIAWQAGHRDVGLLIYVHEQMLRSKLPNRGDATRSSLISPPRHKRQPSQ-----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . : : . * . .. .. : * . ***:*:****::* * : .:.. **.* . : * . * * :.. * :*.:. . . . *. .* : . : .** ::.. : .* ** :..:.* * **. . .** .* *.:. : . . .. * :***** :****::**:*.:.:*::: ::.:**:** :** * *. .. : : . :: .. * * *:*. : .*. .. *. .: *: : : . .... . * *** :.. *:. ..* *... :*: :: ** * . . :: :. :.:: *: * : . : .:: :.: .:.: ... :.:::.. .* * . . : . *.*: :* . .. *.*. *:* .*: * ** * *: * . . . * :***: .... .:.. ... . . : . .: . : **. *::* :: .* : *. . .. * : :.** ** :.:.. * * .. *. ** : ***:*.*****:**:*****: : *:***: .*:**: *.***:::**.:*:.: : . :*.:*** *.*** :*.: *******:***. *** ** .***:* ** **:******:*:**:*.:: **::* ** : * :*::*: ** :* : :*. *::.* : .. . : : ", "identical_positions": 199, "similar_positions": 284, "identity": "14.72%" }, { "cls_id": "homologset.agr.RGD:1308854", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LET2-1", "uniprot_id": "A0ABK0LET2_RAT", "id": "A0ABK0LET2-1", "name": "THUMP domain-containing protein 1", "aln": "MAATAQQSPPSVGGKRKGKSQFLPAKRARRCDAGGPRQLEPGLQGILITCN-MNERKCVEEAYSLLNEYGDDMYGPEKFIDK------DQQPSGSEGEDD---------DAEAALKKEVG--DIKASTEKRLRRFQSVESGANNVVFIRTLG-IEPEKLVHHILQDMYKTK--KKKTRVILRMLPVSGTCKAFLEDMKKYAETFLEPWFK----APNKGTFQIVYKSRNNSHMNREEVIKELAGIVGSLNS--ENKVDLTNPEYTVVVEIIKAVCCLSVVK--DYVLFRKYNLQEVVKSAKD-SRPPPKLGNGKEAQLEPGSKLSQNDPPKGKNNQQAAPESSEELGQTVPGSETQAGSEGGAKPEPESQGSEGPKTKELSLVL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99J36-1", "uniprot_id": "THUM1_MOUSE", "id": "Q99J36-1", "name": "THUMP domain-containing protein 1", "aln": "MATTAQQSPQPVAGKRKGKSQFLPAKRARRGDAGGPRQLEPGLQGILITCN-MNERKCVEEAYSLLNEYGDDMYGPEKFIDK------DQQPSGSEGEDD---------DAEAALKKEVG--DIKASTEKRLRRFQSVESGANNVVFIRTLG-IEPEKLVHHILQDMYKTK--KKKTRVILRMLPISGTCKAFLEDMKKYAETFLEPWFK----APNKGTFQIVYKSRNNSHMNREEVIKELAGIVGSLNS--ENKVDLTNPEYTVVVEIIKAVCCLSVVK--DYVLFRKYNLQEVVKSAKD-SQPHPKLGNGKEAKLEPDSKLSQSDPPEGN---QVAPESIEELGQTEPGSETQAGSEGDAKPEPESQVSEVPKTNENELS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NXG2-1", "uniprot_id": "THUM1_HUMAN", "id": "Q9NXG2-1", "name": "THUMP domain-containing protein 1", "aln": "MAAPAQQTTQPGGGKRKGKAQYVLAKRARRCDAGGPRQLEPGLQGILITCN-MNERKCVEEAYSLLNEYGDDMYGPEKFTDK------DQQPSGSEGEDD---------DAEAALKKEVG--DIKASTEMRLRRFQSVESGANNVVFIRTLG-IEPEKLVHHILQDMYKTK--KKKTRVILRMLPISGTCKAFLEDMKKYAETFLEPWFK----APNKGTFQIVYKSRNNSHVNREEVIRELAGIVCTLNS--ENKVDLTNPQYTVVVEIIKAVCCLSVVK--DYMLFRKYNLQEVVKSPKDPSQLNSKQGNGKEAKLESADKSDQNNTAEGKNN-QQVPENTEELGQTKPTSNPQVVNEGGAKPELASQATEGSKSNENDFS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VZD8-1", "uniprot_id": "THUM1_DROME", "id": "Q9VZD8-1", "name": "THUMP domain-containing protein 1 homolog", "aln": "--------MEPASKKSKMGKNVKFNNNKKKYFHAKRQTLQPGQRGFFATCN-INEKACVRECYNLLNHYADILYGSEKPENEPEKKQPEEGAGGDAGEDDPKPAAGGTSDDDDDLEAAAA--KCREMLSQRKMRFQNVDTNTTNCVFIRTQL-EDPVALGKHIINDIATTG--KSMSRFVLRLVPIEVVCRANMPDIITAAGELFDKHFL----KEP-TSYGIIFNHRYNQQIKRDQIITQLAELVNSKNV--GNKVDLKEAKKSIIVEVLRGWCLLSVID--NYLECKKFNLAELANPSDK------------KSSGEGDSKSETSEVANGNDK-----------------------EQAESSEESKSNDDENKDSTENDK--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53072-1", "uniprot_id": "TAN1_YEAST", "id": "P53072-1", "name": "tRNA acetyltransferase TAN1", "aln": "------------MGEKRNRNGKDANSQNRKKFKVSSGFLDPGTSGIYATCSRRHERQAAQELQLLFEEKFQELYGDIKEGED----ESENDEKKDLSIED------QIKKELQELKGEETGKDLSSGETKKKDPLAFIDLNCECVTFCKTRKPIVPEEFVLSIMKDLADPKNMVKRTRYVQKLTPITYSCNAKMEQLIKLANLVIGPHFHDPSNVKKNYKFAVEVTRRNFNTIERMDIINQVVKLVNKEGSEFNHTVDLKNYDKLILVECFKSNIGMCVVDGDYKTKYRKYNVQQLYESKFR----------------KDEDKSVKQ---------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : .. :: *:** *: **. :*: ...* *::. : :** * :. :: . . :* . *: . : : :: . .* :* * : *::*: . . :* : :: *: *.* : :: . * .: * .: : . * . ::* ::* ::. :* . . :.***.: . ::** ::. :.*:. :*:*: :: :. : .* . ", "identical_positions": 38, "similar_positions": 93, "identity": "9.9%" }, { "cls_id": "homologset.agr.RGD:1308856", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BKD6-1", "uniprot_id": "R144B_MOUSE", "id": "Q8BKD6-1", "name": "E3 ubiquitin-protein ligase RNF144B", "aln": "-----------------------MDSVDGLQCLTMTAENPPSGDLIPAPLVTCKLCLCEQSLDKMTMLQECQCIFCTPCLKQYMVLSIREGCGSPITCPDMVCLNHGTLQETEIACLVPLDEFQLYQRLKFEREVHMDPLRTWCPVADCQTVCHISAGDPGQPVLVECPSCHLKFCSCCKDAWHEESSCRDSQ-SAMP-EHGALFGTDADAPIKQCPVCRIYIERNEGCAQMMCKNCKHTFCWYCLQNLDNDIFLRHYDKGPCRNKLGHSRASVMWNRTQVVGILVGLGVIALVTSPLLLLASPCIICCVCKSCRGKKKKHDPSTT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0M2W6-1", "uniprot_id": "A0ABK0M2W6_RAT", "id": "A0ABK0M2W6-1", "name": "E3 ubiquitin-protein ligase RNF144B", "aln": "MFSLKGSSYPQIFRWIEEAADRLMDSVDGLQCLTMTAENPPSGDLIPAPLVTCKLCLCEQSLDKMTILQECQCIFCTPCLKQYMVLSIREGCGSPITCPDMVCLNHGTLQEAEIACLVPVDEFQLYQRLKFEREVHMDPLRTWCPVADCQTVCHITAGDPGQPVSVECPSCHLKFCSCCKDAWHEESSCRDSQ-SAMP-EHGALFGTDADSPIKQCPVCRIYIERNEGCAQMMCKNCKHTFCWYCLQNLDNDIFLRHYDKGPCRNKLGHSRASVMWNRTQVVGILVGLGVIALVTSPLLLLASPCIICCVCKSCRGKKKKHDPSTT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7Z419-1", "uniprot_id": "R144B_HUMAN", "id": "Q7Z419-1", "name": "E3 ubiquitin-protein ligase RNF144B", "aln": "-----------------------MGSAGRLHYLAMTAENPTPGDLAPAPLITCKLCLCEQSLDKMTTLQECQCIFCTACLKQYMQLAIREGCGSPITCPDMVCLNHGTLQEAEIACLVPVDQFQLYQRLKFEREVHLDPYRTWCPVADCQTVCPVASSDPGQPVLVECPSCHLKFCSCCKDAWHAEVSCRDSQPIVLPTEHRALFGTDAEAPIKQCPVCRVYIERNEGCAQMMCKNCKHTFCWYCLQNLDNDIFLRHYDKGPCRNKLGHSRASVMWNRTQVVGILVGLGIIALVTSPLLLLASPCIICCVCKSCRGKKKKHDPSTT", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.*.. *: *:******..*** ****:*************** **********.****** *:************************:*******:*:**************:** ************* :::.****** ******************* * ****** .:* ** *******::*********:********************************************************************:************************************", "identical_positions": 265, "similar_positions": 24, "identity": "81.29%" }, { "cls_id": "homologset.agr.RGD:1308858", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z8D8-1", "uniprot_id": "D3Z8D8_RAT", "id": "D3Z8D8-1", "name": "", "aln": "MLLWILLLETSLCFAAGNVTGDVCKEKICSCNEIEGDLHVDCEKKGFTSLQRFTAPTSQFYHLFLHGNSLTRLFPNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFRKQTFLGLDDLEYLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYVPITHLDLRGNRLKTLPYEEVLEQIPGIAEILLEDNPWDCTCDLLSLKEWLENIPKNALIGRVVCEAPTRLQGKDLNETTEQDLCPLKNRVDSSLPAPPAQEETFAPGPLPTPFKINGQDEHATPGAVPNGGTKIPGNWQLKIKPTPPIATGSARNKPPVHGLPCPGGCSCDHIPGSGLKMNCNNRNVSSLADLKPKLSNVQELFLRDNKIHSIRRSHFVDYKNLILLDLGNNNIANIENNTFKNLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNLLRSLPVDVFAGVSLSKLSLHNNYFMYLPVAGVLDQLTSIIQIDLHGNPWECSCTIVPFKQWAERLGSEVLMSDLKCETPVNFFRKDFMLLSNDEICPQLYAKISPTLTSHSKNSTGLAETGTHSNSYLDTSRVSISVLVPGLLLVFVTSAFTVVGMLVFILRNRKRSKRRDANSSASEINSLQTVCDSSYWHNGPYNADGAHRVYDCGSHSLSD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q810C1-1", "uniprot_id": "SLIK1_MOUSE", "id": "Q810C1-1", "name": "SLIT and NTRK-like protein 1", "aln": "MLLWILLLETSLCFAAGNVTGDVCKEKICSCNEIEGDLHVDCEKKGFTSLQRFTAPTSQFYHLFLHGNSLTRLFPNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFRKQTFLGLDDLEYLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYVPITHLDLRGNRLKTLPYEEVLEQIPGIAEILLEDNPWDCTCDLLSLKEWLENIPKNALIGRVVCEAPTRLQGKDLNETTEQDLCPLKNRVDSSLPAPPAQEETFAPGPLPTPFKTNGQDEHATPGAVPNGGTKIPGNWQLKIKPTPPIATGSARNKPPVHGLPCPGGCSCDHIPGSGLKMNCNNRNVSSLADLKPKLSNVQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIANIENNTFKNLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNLLRSLPVDVFAGVSLSKLSLHNNYFMYLPVAGVLDQLTSIIQIDLHGNPWECSCTIVPFKQWAERLGSEVLMSDLKCETPVNFFRKDFMLLSNEEICPQLYARISPTLTSHSKNSTGLAETGTHSNSYLDTSRVSISVLVPGLLLVFVTSAFTVVGMLVFILRNRKRSKRRDANSSASEINSLQTVCDSSYWHNGPYNADGSHRVYDCGSHSLSD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96PX8-1", "uniprot_id": "SLIK1_HUMAN", "id": "Q96PX8-1", "name": "SLIT and NTRK-like protein 1", "aln": "MLLWILLLETSLCFAAGNVTGDVCKEKICSCNEIEGDLHVDCEKKGFTSLQRFTAPTSQFYHLFLHGNSLTRLFPNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFRKQTFLGLDDLEYLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYVPITHLDLRGNRLKTLPYEEVLEQIPGIAEILLEDNPWDCTCDLLSLKEWLENIPKNALIGRVVCEAPTRLQGKDLNETTEQDLCPLKNRVDSSLPAPPAQEETFAPGPLPTPFKTNGQEDHATPGSAPNGGTKIPGNWQIKIRPTAAIATGSSRNKPLANSLPCPGGCSCDHIPGSGLKMNCNNRNVSSLADLKPKLSNVQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVENNTFKNLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNLLRSLPVDVFAGVSLSKLSLHNNYFMYLPVAGVLDQLTSIIQIDLHGNPWECSCTIVPFKQWAERLGSEVLMSDLKCETPVNFFRKDFMLLSNDEICPQLYARISPTLTSHSKNSTGLAETGTHSNSYLDTSRVSISVLVPGLLLVFVTSAFTVVGMLVFILRNRKRSKRRDANSSASEINSLQTVCDSSYWHNGPYNADGAHRVYDCGSHSLSD", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*************************************************************************************************************************************************************************************************************************************************************************************************** ***::*****:.************:**:**..*****:**** .:.*****************************************************:********************.:****************************************************************************************************************************************************************:********:**************************************************************************************************:*************", "identical_positions": 676, "similar_positions": 18, "identity": "97.13%" }, { "cls_id": "homologset.agr.RGD:1308859", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q4KM97-1", "uniprot_id": "Q4KM97_RAT", "id": "Q4KM97-1", "name": "Tyrosine-protein kinase", "aln": "MG-LLSSKRQ-----ISEKSKS-----WSPVKARAQGKVPPPLPPLVVFNHLPPPSPNQHPDEEERFVVALFDYAAVNDRDLQVLKGEKLQVLKST-GDWWLARSLVTGREGYVPSNFVAPVETLEVEKWFFRTISRKDAERQLLAPMNKAGSFLIRESESNKGAFSLSVKDVTS-QGEMVKHYKIRSLDNGGYYISPRITFPTLQALVQHYSEKGDGLCQKLTLPCVNPAP-----KNPWAQDEWEIPRQSLKLVRKLGSGQFGEVWMGYYKNNMKVAIKTLKEGTMSPEAFLGEANVMKTLQHERLVRLYAVVT-REPIYIVTEYMARGCLLDFLKTDEGS--RLSLPRLIDMSAQVAEGMAYIERMNSIHRDLRAANILVSETLCCKIADFGLARIIDS-EYTAQEGAKFPIKWTAPEAIHFGVFTIKADVWSFGVLLMEIVTYGRVPYPGMSNPEVIRSLEHGYRMPCPETCPPELYHDVITECWRGRPEERPTFEFLQSVLEDFYTATEGQYELQP--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P16277-1", "uniprot_id": "BLK_MOUSE", "id": "P16277-1", "name": "Tyrosine-protein kinase Blk", "aln": "MG-LLSSKRQ-----VSEKGKG-----WSPVKIRTQDKAPPPLPPLVVFNHLAPPSPNQDPDEEERFVVALFDYAAVNDRDLQVLKGEKLQVLRST-GDWWLARSLVTGREGYVPSNFVAPVETLEVEKWFFRTISRKDAERQLLAPMNKAGSFLIRESESNKGAFSLSVKDITT-QGEVVKHYKIRSLDNGGYYISPRITFPTLQALVQHYSKKGDGLCQKLTLPCVNLAP-----KNLWAQDEWEIPRQSLKLVRKLGSGQFGEVWMGYYKNNMKVAIKTLKEGTMSPEAFLGEANVMKTLQHERLVRLYAVVT-REPIYIVTEYMARGCLLDFLKTDEGS--RLSLPRLIDMSAQVAEGMAYIERMNSIHRDLRAANILVSETLCCKIADFGLARIIDS-EYTAQEGAKFPIKWTAPEAIHFGVFTIKADVWSFGVLLMEIVTYGRVPYPGMSNPEVIRSLEHGYRMPCPETCPPELYNDIITECWRGRPEERPTFEFLQSVLEDFYTATEGQYELQP--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P51451-1", "uniprot_id": "BLK_HUMAN", "id": "P51451-1", "name": "Tyrosine-protein kinase Blk", "aln": "MG-LVSSKKPDKEKPIKEKDKGQ----WSPLKVSAQDKDAPPLPPLVVFNHLTPPPPDEHLDEDKHFVVALYDYTAMNDRDLQMLKGEKLQVLKGT-GDWWLARSLVTGREGYVPSNFVARVESLEMERWFFRSQGRKEAERQLLAPINKAGSFLIRESETNKGAFSLSVKDVTT-QGELIKHYKIRCLDEGGYYISPRITFPSLQALVQHYSKKGDGLCQRLTLPCVRPAP-----QNPWAQDEWEIPRQSLRLVRKLGSGQFGEVWMGYYKNNMKVAIKTLKEGTMSPEAFLGEANVMKALQHERLVRLYAVVT-KEPIYIVTEYMARGCLLDFLKTDEGS--RLSLPRLIDMSAQIAEGMAYIERMNSIHRDLRAANILVSEALCCKIADFGLARIIDS-EYTAQEGAKFPIKWTAPEAIHFGVFTIKADVWSFGVLLMEVVTYGRVPYPGMSNPEVIRNLERGYRMPRPDTCPPELYRGVIAECWRSRPEERPTFEFLQSVLEDFYTATERQYELQP--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6YUU4-1", "uniprot_id": "A0A8M6YUU4_DANRE", "id": "A0A8M6YUU4-1", "name": "Tyrosine-protein kinase", "aln": "ML-INPTQEDD---HISFLRMG-----CACSDQNHPKGHEHYNSTNSKTSHASRDHKKQNNNQDEDVVIAQYDFQPASENDLQFKKGDRLRIIKEN-GEWWLAKSLVTGYEGFIPSTYVARAQTLQVERWFFKDMNRRDTERLLLAPGNKPGSFLVRESETTKGAFSLSIRDSTPEQGDVVKHYKIRALDNGGYYISPSTSFSSLQELVKYYSRTADGLCQRLGNPCKSTAP-----QRPWAQDEWEIPRETLKLVKKLGAGQFGEVWMGFYKNNQKVAIKTLKEGTMEPEAFLQEANLMKQLQHERLVKLHAVVT-REPIYIVTEYMANGSLLDFLKTDDGH--KLKLSKLIDMTAQIAEGMAYIERKNYIHRDLRAANILVSETLHCKIADFGLARIIET-EYTAQEGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTYGRVPYPGMTNPEVIRNLDRNYRMPCPDACPGELY-DIMTKCWMEKPEDRPTFEYLQDTLNDFFIATEGQYEMQP--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V9J3-1", "uniprot_id": "SRC42_DROME", "id": "Q9V9J3-1", "name": "Tyrosine-protein kinase Src42A", "aln": "MGNCLTTQKGEPDKPADRIKLDDPPTIGVGVGVPQIPMPSHAGQPPEQIRPVPQIPESETAGANAKIFVALYDYDARTDEDLSFRKGEHLEILNDTQGDWWLARSKKTRSEGYIPSNYVAKLKSIEAEPWYFRKIKRIEAEKKLLLPENEHGAFLIRDSESRHNDYSLSVR-----DGDTVKHYRIRQLDEGGFFIARRTTFRTLQELVEHYSKDSDGLCVNLCKPCVQIEKPVTEGLSHRTRDQWEIDRTSLKFVRKLGSGQFGDVWEGLWNNTTPVAIKTLKSGTMDPKDFLAEAQIMKKLRHTKLIQLYAVCTVEEPIYIITELMKHGSLLEYLQAIAGKGRSLKMQTLIDMAAQIAAGMAYLESQNYIHRDLAARNVLVGDGNIVKIADFGLARLIKEDEYEARVGARFPIKWTAPEAANYSKFSIKSDVWSFGILLTELVTYGRIPYPGMTNAEVLTQVEHGYRMPQPPNCEPRLY-EIMLECWHKDPMRRPTFETLQWKLEDFYTSDQSDYKEAQAY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* .::. . . . . .: . : ..:* :*: . .:.**.. **::*.::. . *:****:* * **::**.:** :::: * *:*: * ::*: ** * *: *:**:*:**: :. :***:: :*: :***:** **:**::*: :* :** **::**. .**** .* ** ::*:*** * :*::*:***:****:** * ::*. *******.***.*: ** **::** *:* :*::*:** * .*****:** * .*.**::*:: * *.: ****:**:* ****:* * ***** * *:**.: *********:*. ** *: **:********** ::. *:**:******:** *:*****:*****:*.**: .:::.**** * * .** :: :** * ***** ** *:**: : : :*: ", "identical_positions": 214, "similar_positions": 138, "identity": "40.92%" }, { "cls_id": "homologset.agr.RGD:1308860", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZNV5-1", "uniprot_id": "D3ZNV5_RAT", "id": "D3ZNV5-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------MGCNLCT----------------------------------------------------------------------------------FQKREEHYKLLYEVS------------------------------------------------------------------------------QVNGKDLSKATHEEAVEAFRTAKEPIVVQVLRRTPLSRPPYGMAPEVQLMNASTQTDITFEHIMALAKLRPLTPPVPDTCPFLLSDSCHSLHPMERAFYEDHEYVSSLPADADRAEDFEYEEVELCRVSSQEKLGLTVCYRTDDEEDTGIYVSEVDPNSIAAKDGRIREGDRILQINGEDIQNREEAVALLS--SDECKRIVLLIARPDLQLDEGWLEDERNEFLEELNSEMLEEERNEGAQCTANELQQPKKQEEEEGTTDTATSSSNNQEKDSGVGRTDESLRNDESSEQENVVEEPHS-TALKSKRELGQSQDTLGSIELQCNQSCAGGECLDSDCASN-QEVCEGFQQLLELK--IRNHGDYDLYYSSSTLECNQGEQDGVEHELKLLNEELRNIELECQN-----IMQAHRLQKVTDQYGDIWALHDGGFRNYNTSLDMQRGKLDDIIEHPEKSDKDSSSAYNTAESCR-STPLTVDRSPDSSLP--RMINLTNKKNLRSMMTAHQSPSRPSTREYTATKVKTTHEGCSVESLEKSLENSQLLDQEHTVSEHTPYLSPYHSSSYRYANIPAHARHYQSYMQLIQQKSAVEYAQSQLSLVS--MCKESPRGSEPKMEWKVKIRSDGTRYITKRPVRDRLLKERALKIKEERSGMTTDDDTMSEMKMGRYWSKEERKQHLVRAKEQRRRREFMMRSRLESLKESPQSSGEGKKELSIIELSHKKMMKKRNKKILDNWMTIQELMTHGAKSPDGTRVHNAFLSVTTV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9PUZ9-1", "uniprot_id": "E9PUZ9_MOUSE", "id": "E9PUZ9-1", "name": "", "aln": "MGFALERLAEAVDPAFQCQLLCGQVLEEPACTPCGHVFCASCLLPWAAGRRWCPLQCQPLAPGELYRVLPLRSLVQQLRVQCNYSGQGCGHRG-----DCGCWQCTSSAAPSALPAAVTATAQAAAEAAGRKSTRRPRPAGVGTRVRGHPD--------------LEVGLWLSPAVGVGKTRRAQVSLLQRRYQEKLALYMAHTRNFVGNPGG-RGQDGEQKPFTVVLEREDDTLGFNIIGGRPYQNSQKQSAPEGIYVSKILENGPADRADGLEVHDKIIAVNGRDLSKATHEEAVEAFRTAKEPIVVQVLRRTPLSRPTYGMTPEVQLTNASTQTDITFEHIMALAKLRPLTPPVPDTCPFLLSDSCHSLHPMEHGFYEDHEYVSSLPADADRADDFEYEEVELCRVSSQEKLGLTVCYRTDDEEDTGIYVSEVDPNSIAAKDGRIREGDRILQINGEDIQNREEAVALLS--SDECKRIVLLIARPDMQLDEGWLEDERNEFLEELNSELLEEDHNEGAQRTASELQQPKKQEEEEGTTDTATSSSNNQEKDSGVGRTDESLRNDESSEQENAVEEPHS-TTLKSKRELGKSQDTLGSLEHQCSESCAGGECLDSDCASN-QEVCEGFQQLLELK--IRNHGDYDLYYSSSTIECNRGEQDGVEHELQLLNEELRNIELECQN-----IMQAHRLQKVTDQYGDIWALHDGGFRNYNTSLDVQRGKLDDIMEHPEKSDKDSSSAYNTAESCR-STPLTVDRSPDSSLP--RMINLTNKKNLRSMMTAHQSPPRQSTREYTSTKVKATDEGCSVESLEKGLESSQLLDQEHTVSEHPPYLSPYHSSSYRYANIPAHARHYQSYMQLIQQKSAVEYAQSQLSLVS--MCKESQRGSEPKMEWKVKIRSDGTRYITKRPVRDRLLKERALKIKEERSGMTTDDDTMSEMKMGRYWSKEERKQHLVRAKEQRRRREFMMRSRLESLKESPQSSGEGKKELSIIELSHKKMMKKRNKKILDNWMTIQELMTHGAKSPDGTRVHNAFLSVTTV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZMN7-1", "uniprot_id": "PZRN4_HUMAN", "id": "Q6ZMN7-1", "name": "PDZ domain-containing RING finger protein 4", "aln": "MGFALERFAEAVDPALECK-LCGQVLEEPLCTPCGHVFCASCLLPWAVRRRRCPLQCQPLAPGELYRVLPLRSLIQKLRVQCDYRARGCGHSVRLHELEAHVEHCDFGPARRLRSRGGCASGLGGGEVPARGGCGPTPRAGRGGGARGGPPGGRWGRGRGPGPRVLAWRRREKALLAQLWALQGEVQLTARRYQEKFTQYMAHVRNFVGDLGGGHRRDGEHKPFTIVLERENDTLGFNIIGGRPNQNNQEGTSTEGIYVSKILENGPADRADGLEIHDKIMEVNGKDLSKATHEEAVEAFRNAKEPIVVQVLRRTPLSRPAYGMASEVQLMNASTQTDITFEHIMALAKLRPPTPPVPDICPFLLSDSCHSLHPMEHEFYEDNEYISSLPADADRTEDFEYEEVELCRVSSQEKLGLTVCYRTDDEEDTGIYVSEVDPNSIAAKDGRIREGDRILQINGEDVQNREEAVALLS--NDECKRIVLLVARPEIQLDEGWLEDERNEFLEELNLEMLEEEHNEAMQPTANEVEQPKKQEEEEGTTDTATSSSNNHEKDSGVGRTDESLRNDESSEQENAAEDPNS-TSLKSKRDLGQSQDTLGSVELQYNESLVSGEYIDSDCIGNPDEDCERFRQLLELKCKIRNHGEYDLYYSSSTIECNQGEQEGVEHELQLLNEELRNIELECQN-----IMQAHRLQKVTDQYGDIWTLHDGGFRNYNTSIDMQRGKLDDIMEHPEKSDKDSSSAYNTAESCR-STPLTVDRSPDSSLP--RVINLTNKKNLRSTMAATQSSSGQSSKESTSTKAKTTEQGCSAESKEKVLEGSKLPDQEKAVSEHIPYLSPYHSSSYRYANIPAHARHYQSYMQLIQQKSAVEYAQSQLSLVS--MCKESQKCSEPKMEWKVKIRSDGTRYITKRPVRDRILKERALKIKEERSGMTTDDDTMSEMKMGRYWSKEERKQHLVRAKEQRRRREFMMRSRLECLKESPQSGSEGKKEINIIELSHKKMMKKRNKKILDNWMTIQELMTHGAKSPDGTRVHNAFLSVTTV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8MR31-1", "uniprot_id": "SLIP1_DROME", "id": "Q8MR31-1", "name": "Slo-interacting protein 1", "aln": "------------------------------------------MSIADVEYEYVVLKINGYDISHLSRYEAVQKFLQSK--------------------------------------------------------------------------------------------------------ETLVVEIRRQKHNALDLELKHGSN-------------------------------------------------------------AKISKVDNPGELSVLTDKSAEGTITAASASQQINCPSSTSLKEIETKTPVVLTLRARSHEDRLGSLQAASKETQTQSVVGTDVLKDNDLVNTITDNFIEHEHHLFEQCLEPEIDIEEVTLVKGVEQSSSNQIGLIVTSSGIQQSSTDTNKGDILGNVLEHSEDVFISGVQPESIAYRDGRLRQGDQILRINGLDVKNQEELETQIARSSTSVTLLVSRILYPEDDDDEDIHFEYANTFLPDDYTNVVDK-LDKVLLTHVKSLEELSNKSAMQSDECYHIPEKNSSDSNVKISSLAKNIIEQSTKSCSKIKLRPNANLDYKKKFNLPLSQEEV-HLQYEYDESEHIYETIPEDSESE-PVYCSPYQRSNDKTS-IGCSSPIASRPAESLERTMQQQTQRVAQWLGLKPQYQKTRQTLVGRPPPLKLVQQPTCSRVFTLRSTLTNTSASSSSGVAYSSYGQNNVVTGNAAAPGEEVDNSSSAYNTGDSNNSASPHQNTTNPDEAIATGRKLDSTVIDSPNDHLDATGVSTMLLLPFGKSGRIGLCSSNLPTAYVSERYTNVGSENEIHPLKSDIEILR-VKPTDDSYSHCPQFNAPNLSSYHFVSSQEVANRCHISTSLQKNATLLNGESAEEIPMVWKVKRRPDGTRYIVKRPVRNRPQVALRKNMRYN-EVTTTEDDTISEVKIGRYWTKEERKRHIERAREKRHHQTQQQQQ----------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: .. .: .. * .* : :. .... : :: :**: . . : * :* . .: :. * : :. :.: . * ::... * :. . : .* .: . :::: .. .*. . . . *.. .:::* *:*:*** :***:*:**:**:*** *::*:** : :: . . . :* : *: : **. : * ** : ::::: :: ...::: .::. :. ...*. :.: :. :.: ::.:.. .: *:: *.* :* **: : :: : .:* * : .*. .: *. ::: : . * . :.* . : : : * : * * : :. : . ::* .:* . : .. . * *.. : . * :. .:*******.:* . ::* .**.::. * :: * .. .. : * .. .: : .. .. .: . :: :.:... * :.:. *:: * . * :::..:...: .: . ** . :. .* * **** *.******.*****:* ::: : . **:***:**:*:****:*****:*: **:*:*::: :. ", "identical_positions": 122, "similar_positions": 264, "identity": "11.62%" }, { "cls_id": "homologset.agr.RGD:1308861", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D119-1", "uniprot_id": "PPR27_MOUSE", "id": "Q9D119-1", "name": "Protein phosphatase 1 regulatory subunit 27", "aln": "-------MPSRTVRYARYSP--------RQRRRRMLADRSVRFPNDVLFLDHIRQGDLEQVGRFIRARKVSLDTIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQ---RDETGWTPLHIACSDGYPD------IARYLISLGADRDAANDDGDLPSDLID-PDFKDLVELFKGTSMD-------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZXG0-1", "uniprot_id": "D3ZXG0_RAT", "id": "D3ZXG0-1", "name": "Protein phosphatase 1 regulatory subunit 27", "aln": "-------MPSRTVRYARYSP--------RQRRRRLLADRSVRFPNDVLFLDHIRQGDLEQVGRFIRARKVSLDTIYPSGLAALHEAVLSGNLECVKLLVKYGADIHQ---RDETGWTPLHIACSDGYPD------IARYLISLGADRDATNDDGDLPSDLID-PDFKDLVELFKGTSMD-------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q86WC6-1", "uniprot_id": "PPR27_HUMAN", "id": "Q86WC6-1", "name": "Protein phosphatase 1 regulatory subunit 27", "aln": "-------MPSRTARYARYSP--------RQRRRRMLADRSVRFPNDVLFLDHIRQGDLEQVGRFIRTRKVSLATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQ---RDEAGWTPLHIACSDGYPD------IARYLISLGADRDATNDDGDLPSDLID-PDYKELVELFKGTTMD-------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N852-1", "uniprot_id": "A0A8M1N852_DANRE", "id": "A0A8M1N852-1", "name": "", "aln": "MLKFFLCPVTQTMHYGICNPNTTDPLSCSRSQSSIKSARIVHFPNDIVFQDCVRQGELERVGCFIQTRRVSLDTIYHSGMAAIHEAVLSGNMECVKLLVKSGADITQ---RDEDGWTPLHMACSDGFPE------IAKYLISLGADTEAKNDCGEKPADLID-PDCKELLHLF-GVGGD-------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P53066-1", "uniprot_id": "YGZ2_YEAST", "id": "P53066-1", "name": "Ankyrin repeat-containing protein YGL242C", "aln": "-------MNTEGASLS---------------EQLLDAARRNNLDLLETVFDSLDN-DPEKIAKLINESKE------PLGNTALHLCCKYGSWEVLDKILDQDGEIEIDPQNDVDGDTPLHVTVRYSQEEPEHGTFIARNLIEVGADPRVRNYNNQKPVDLVHGDELDELIDLLQGAELAIDSTNGSGDNNEDGEMIDDGPSDDDEEDDKK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . . : : * .: . * : : : *::. :*. : * :*:* . *. * :. ::. ..:* .* * ****:: . : **: **.:*** . * .: * **:. : .:*:.*: *. ", "identical_positions": 30, "similar_positions": 50, "identity": "14.29%" }, { "cls_id": "homologset.agr.RGD:1308863", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q4QQW3-1", "uniprot_id": "HOT_RAT", "id": "Q4QQW3-1", "name": "Hydroxyacid-oxoacid transhydrogenase, mitochondrial", "aln": "MAAAARARVTHLLRHLQSTACQCPTHSHTY-SQVPGLSPSGKTTDYAFEMAVSNIRYGAGVTKEVGMDLQNMGAKNVCLMTDKNLSQLPPVQIVMDSLSKNGISFQVYDNVRVEPTDGSFMDAIEFAKKGAFDAYVAVGGGSTMDTCKAANLYACSPHSEFLDYVNAPIGKGKPVTVPLKPLIAVPTTSGTGSETTGVAIFDYEHLKVKTGIASRAIKPTLGLVDPLHTLHMPCQVVANSGFDVLCHALESYTAIPYSMRSPCPSNPIQRPAYQGSNPISDIWAVHALRIVAKYLKRAVRNPDDLEARSSMHLASAFAGIGFGNAGVHLCHGMSYPISGLVKTYKAKEYNVDHPLVPHGLSVVLTSPAVFTFTAQMFPERHLETAEILGANIRTAKIQDAGPVLADALRKFLFDLNVDDGLAALGYSKDDIPSLVKGTLPQERVTKLAPRAQSEEDLSALFEASMKLY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R0N6-1", "uniprot_id": "HOT_MOUSE", "id": "Q8R0N6-1", "name": "Hydroxyacid-oxoacid transhydrogenase, mitochondrial", "aln": "MAAAARARVTHLLRHLQSTACQCPTHSHTY-SQAPG--PSGKTADYAFEMAVSNIRYGAGVTKEVGMDLQNMGAKNVCLMTDKNLSQLPPVQIVMDSLSKNGISFQVYDDVRVEPTDGSFMDAIEFAKKGAFDAYVAVGGGSTMDTCKAANLYASSPHSEFLDYVNAPIGKGKPVTVPLKPLIAVPTTSGTGSETTGVAIFDYEHLKVKTGIASRAIKPTLGLVDPLHTLHMPCQVVANSGFDVLCHALESYTAIPYSMRSPCPSNPIQRPAYQGSNPISDIWAVHALQIVAKYLKRAVRNPDDLEARSKMHLASAFAGIGFGNAGVHLCHGMSYPISGLVKTYKAKEYNVDHPLVPHGLSVVLTSPAVFTFTAQMFPERHLETAGILGANIRTARIQDAGLVLADALRKFLFDLNVDDGLAALGYSKDDIPSLVKGTLPQERVTKLAPRAQSEEDLSALFEASMKLY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IWW8-1", "uniprot_id": "HOT_HUMAN", "id": "Q8IWW8-1", "name": "Hydroxyacid-oxoacid transhydrogenase, mitochondrial", "aln": "MAAAARARVAYLLRQLQRAACQCPTHSHTY-SQAPGLSPSGKTTDYAFEMAVSNIRYGAAVTKEVGMDLKNMGAKNVCLMTDKNLSKLPPVQVAMDSLVKNGIPFTVYDNVRVEPTDSSFMEAIEFAQKGAFDAYVAVGGGSTMDTCKAANLYASSPHSDFLDYVSAPIGKGKPVSVPLKPLIAVPTTSGTGSETTGVAIFDYEHLKVKIGITSRAIKPTLGLIDPLHTLHMPARVVANSGFDVLCHALESYTTLPYHLRSPCPSNPITRPAYQGSNPISDIWAIHALRIVAKYLKRAVRNPDDLEARSHMHLASAFAGIGFGNAGVHLCHGMSYPISGLVKMYKAKDYNVDHPLVPHGLSVVLTSPAVFTFTAQMFPERHLEMAEILGADTRTARIQDAGLVLADTLRKFLFDLDVDDGLAAVGYSKADIPALVKGTLPQERVTKLAPCPQSEEDLAALFEASMKLY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W265-1", "uniprot_id": "HOT_DROME", "id": "Q9W265-1", "name": "Probable hydroxyacid-oxoacid transhydrogenase, mitochondrial", "aln": "---MSRKNVLGLINTIVANSCKCPAHSHNYGSAAPTASQTGR-MEYAFEMSASTVRFGPGVSAEVGADLRNLGARKVCLVTDKNVVQLPSVKVALDSLARNGINYEVYDETRVEPTDGSMWHAVEFARGKEFDAFLAIGGGSAMDTAKAANLFSSDANAEFLDYVNCPIGRGKEISVKLKPLIAMPTTSGTGSETTGVAIFDYKKLHAKTGISSKFLKPTLAVIDPLHTLSQPQRVMAFAGFDVFCHALESFTAVDYRERGLAPSDPSLRPTYQGRNPVSDVWARFALETIRKNFVNAIYQPDNLEARSQMHLASTMAGVGFGNAGVHLCHGLSYPISGNVRDYKPKGYSADHALIPHGLSVVISAPAVFEFTAPACPDRHLEAAQLLGAEVRGVEKADAGRLLADTVRGFMQRAGIENGLRELGFSSSDIPALVEGTLPQERITKLAPRAQTQENLSQLFEKSMEVY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P10127-1", "uniprot_id": "ADH4_YEAST", "id": "P10127-1", "name": "Alcohol dehydrogenase 4", "aln": "----------------MSSVTGFYIPPISF--------------------------FGEGALEETADYIKNKDYKKALIVTDPGIAAIGLSGRVQKMLEERDLNVAIYDKTQPNPNIANVTAGLKVLKEQNSEIVVSIGGGSAHDNAKAIALLATN-GGEIGDYEGVNQSKK-----AALPLFAINTTAGTASEMTRFTIISNEEKKIKMAIIDNNVTPAVAVNDPSTMFGLPPALTAATGLDALTHCIEAYVST-------------------ASNPITDACALKGIDLINESLVAAYKDGKDKKARTDMCYAEYLAGMAFNNASLGYVHALAHQLGG-------------FYHLPHGVCNAVLLPHVQEANMQCPKAKKRLGEIALHFGASQEDPEET----IKALHVLNRTMNIPRNLKELGVKTEDFEILAEHAMH-DACHLTNPVQFTKEQVVAIIKKAYEY-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .: :* .. *.. ::* . ::. ::** .: : . . * ...: :**..: :*. ... .::. : : :::****: *..** * : . .:: ** . .: **:*: **:**.** * .:*:. :. : * .* .. :.*::.: ** : * : * :*:*.: *.:*::.: . **::* * .: : : : * : .: :**: * *. :**:.*.**.: *.::: :.* . :***:. .: * * . :: * :: .::: : .: .* :* .. *: *.: :: : * ::*:: ::: : : ", "identical_positions": 69, "similar_positions": 149, "identity": "14.74%" }, { "cls_id": "homologset.agr.RGD:1308864", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P56959-1", "uniprot_id": "FUS_MOUSE", "id": "P56959-1", "name": "RNA-binding protein FUS", "aln": "MASNDYTQQATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYGQSADTSGYGQSSYGSSYGQTQNTGYGTQSAPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGGSSQSSSYGQPQSGGYGQQSGYGGQQQSYGQQQSSYNPPQGYGQQNQ-YNSSSGGGGGGGGG-NYGQDQSSMSGGGG-GGGYGNQDQSGGGGGGYGGGQQDRGGRGRGG--------GGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGG-FPSGGGGGGG-----------------QQRAGDWKCPNPTCENMNFSWRNECNQCKAPKPD-------GPGGGPGGSHMGGNY--GDDRRG-RGGYD---RGGYRGRGGDRGGFRGGRG------GGDRGGFGPGKMDSR--GEHRQDR--RERPY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5PQK2-1", "uniprot_id": "Q5PQK2_RAT", "id": "Q5PQK2-1", "name": "RNA-binding protein FUS", "aln": "---TDYTQQATQSYGAYPTQPGQGYSQQSNQPYGQQSYSGYGQSADTSGYGQSSYGSSYGQTQNTGYGTQSAPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGGSSQSSSYGQPQSGGYGQQSGYGGQQQSYGQQQSSYNPPQGYGQQNQ-YNSSSGGGGGGGGG-NYGQDQSSMSGGGG-GGGYGNQDQSGGGGGGYGGGQQDRGGRGRGG--------GGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGG-FPSGGGGGGG-----------------QQRAGDWKCPNPTCENMNFSWRSECNQCKAPKPD-------GPGGGPGGSHMGGNY--GDDRRG-RGGYD---RGGYRGRGGDRGGFRGGRG------GGDRGGFGPGKMDSR--GEHRQDR--RERPY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P35637-1", "uniprot_id": "FUS_HUMAN", "id": "P35637-1", "name": "RNA-binding protein FUS", "aln": "MASNDYTQQATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSY-SSYGQSQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQS-YNPPQGYGQQNQ-YNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSG-GYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGG-FPSGGGGGGG-----------------QQRAGDWKCPNPTCENMNFSWRNECNQCKAPKPD-------GPGGGPGGSHMGGNY--GDDRRGGRGGYD---RGGYRGRGGDRGGFRGGRG------GGDRGGFGPGKMDSR--GEHRQDR--RERPY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q27294-1", "uniprot_id": "CAZ_DROME", "id": "Q27294-1", "name": "RNA-binding protein cabeza", "aln": "--------------------------------------------MERGGYG-----GGSGQ----GYNNFAVPP------------------------PNYQQMPN--------------------KTGNYNE-------------------PPPNYGKQGGGYDSGSGHRGSGGSG----------NGGGG-GGSWNDR---GGNSYGNGGASKD------------------SYNKGHGGYSGGGGGGGGGGGGGSGGND---------------------MITQEDTIFVSGMDPSTTEQDIETHFGAIGIIKKDKRTMKPKIWLYKNKETGASKGEATVTYDDTNAAQSAIEWFDGRDFNGNAIKVSLAQRQNNWNKGGGGGGGGGGRGGFGGRRGGGGGGGGGGGGGGRFDRGGGGGGGRYDRGGGGGGGGGGGNVQPRDGDWKCN--SCNNTNFAWRNECNRCKTPKGDDEGSSGGGGGGGYGGGGGGGGYDRGNDRGSGGGGYHNRDRGGNSQGGGGGGGGGGGYSRFNDNNGGGRGGRGGGGGNRRDGGPMRNDGGMRSRPY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .*** .. ** **.. :.* *.* * * ::*.*.: ** .**:*. *:*.** *.**.* ..*** **.:.:: **.. * * ..:* .**:. ***. * *** ** ** **.* ::::****.*:. ..* :.: :* *****.:*:* :* * **.::*** ******::**. :*::**:****::*.**.****:* *: ::*:***.* ** **** ** * ****.**** ** * ******* * * ***** :*:* **:**.***:**:** * * *** **. **.* *:** . ***. *** **. ** ** . **.*** * * : * * *:* *.***", "identical_positions": 190, "similar_positions": 93, "identity": "33.33%" }, { "cls_id": "homologset.agr.RGD:1308865", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q7TQC7-1", "uniprot_id": "GPTC2_MOUSE", "id": "Q7TQC7-1", "name": "G patch domain-containing protein 2", "aln": "-------MFGADGRPAIGTAAG----------------------KSWHFS----------------------RTMEELVHDLVSALEESSEQARGGFAETGEHSRNLSCPLKRQARKRR----GRKRRSYN----------VHHPWETGHCLSEGSDSSLEEPSKDYREKHSNNKKDRSDSDD--QMLVAKRRPSSNLSSSVRGKRLLWHESDFAVDS----LGNRTLRRRRKVKRMAVDLPQDVSSKRTMTQLPEGCRDQ----DMDNDRASQYPEFT------------------------RKKVKKRKLKGIRPGPKTQEEGGVLESEERSQPNKDRMEYEEQKASDELRSESDT-----------------------------------------------------------------------------------------------------SSLSSTDAGLFTNDEGRQGDDEQSDWFYEKE--------SGGACGIAGVVPWWEKDEPAELDTNLPDPVFESILSGSFPLMSHPGRGGFQARLSRLHGTPSKNIKKSSG---APPSMLSAPGPGSNKRMVHFSPDAHRHDHWFSPGARTEHGQHQLLRDNRAERGHKKSCSLKTASRQTSMHLG-----SLCTGDIKRRRKAAP-----------------------------------LPG--PTAAG-IVGENAQPILESNIGNRMLQSMGWTPGSGLGRDG-RGIAEPVQAVQRPKGLGLGFPLPKSSPTSPAPTSGNPA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GC35-1", "uniprot_id": "A0A8I6GC35_RAT", "id": "A0A8I6GC35-1", "name": "", "aln": "-------MFGADGRPAIGAAAAAR--------------------KSWHFS----------------------RTMEELVHDLVSALEESSEQARGGFAETGDHSRNLSCPLKRQARKRR----GRKRRSYN----------VHHPWETGHCLSEGSDSSLEEPSKDYREKHSNNKKDRSDSDD--QMLVAKRRPSSTLNNSVRGKRLLWHESDFAVDN----LGNRTLRRRRKVKRMAVDLPQDISTKRTMTQPPDGCRDQ----DMDSDGASQYPEFI------------------------RSKVKKRRLKVIR--PKAPEEGAVLESEEVSQADKDKMEYVEPKASDELRSESDS-----------------------------------------------------------------------------------------------------SSLSSTDAGLFTNDEGRQGDDEQSDWFYEKE--------SGGACGIAGVAPWWEEEGPVELDTNLPDPVFESILSGSFPLMSHPGRRGFQARLSCLHGVPSKNIKKSAG---APPSMMSAPGPISNKRMVHFSPDAHHHDHWFSPGARTEHGQHQLLRDNRAERGHKKSCSVKTASRQTSMHLG-----SLCTGDIKRRRKAAP-----------------------------------LPGPGPTTTG-IVGENAQPILESNIGNRMLQSMGWTPGAGLGRDG-RGISEPVQAIQRPKGLGLGFPLPKSTPTSPVPASGKPA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NW75-1", "uniprot_id": "GPTC2_HUMAN", "id": "Q9NW75-1", "name": "G patch domain-containing protein 2", "aln": "-------MFGAAGRQPIGAPAAG---------------------NSWHFS----------------------RTMEELVHDLVSALEESSEQARGGFAETGDHSRSISCPLKRQARKRR----GRKRRSYN----------VHHPWETGHCLSEGSDSSLEEPSKDYRENHNNNKKDHSDSDD--QMLVAKRRPSSNLNNNVRGKRPLWHESDFAVDN----VGNRTLRRRRKVKRMAVDLPQDISNKRTMTQPPEGCRDQ----DMDSDRAYQYQEFT------------------------KNKVKKRKLKIIRQGPKIQDEGVVLESEETNQTNKDKMECEEQKVSDELMSESDS-----------------------------------------------------------------------------------------------------SSLSSTDAGLFTNDEGRQGDDEQSDWFYEKE--------SGGACGITGVVPWWEKEDPTELDKNVPDPVFESILTGSFPLMSHPSRRGFQARLSRLHGMSSKNIKKSGG---TPTSMVPIPGPVGNKRMVHFSPDSHHHDHWFSPGARTEHDQHQLLRDNRAERGHKKNCSVRTASRQTSMHLG-----SLCTGDIKRRRKAAP-----------------------------------LPG--PTTAG-FVGENAQPILENNIGNRMLQNMGWTPGSGLGRDG-KGISEPIQAMQRPKGLGLGFPLPKSTSATTTPNAGKSA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P53866-1", "uniprot_id": "SQS1_YEAST", "id": "P53866-1", "name": "Protein SQS1", "aln": "MAKRHSHYQGSRRRHARGSNSKKAGRGNAKGIQGRKIKKKPTPTNSWHNSSIPLGEGDLDDVGADFNPGRAFISPKTIEDYYFGRDAKSRSMKMGGLRPGNRYDSSTDLQAGRAAFRKRPMQFVKAKEVYDPSHNMIQKLRAKNETKNSEEIVEREADVFEEPGKMTSDVEYINNEDSENEDDDSQNSPSTDHSLSSNESKVEDGDLFFVDEEAQQSPDLTKIKRVCIEEIARPREVAIEFDPILTIGKVELSVSEGNESKEISVDVPNKGNKTYHPFAGYISNVLHGMHTSDSDNDELDYEIETENNSEPLYESSASSEVDQGFNYVGQRHNSRADNNLLPSPSPQLTEDIKCLSINGTKTFEGNNDNLPSPASEELEFGFKEEDFVINTNDIVVSNIRMGGVDNSYYLRCYRLLGDYDFHWIDQDLLTDFVVDELGLPEDRLPAYLNFIKNSLIPKIEPAEPTYSDIPISDSSDEGDSYEGDSYEDDEDMASSVVHSDIEEGLDDLIAYTLKHDTERFKTFETKSLETKGKGKKKKLLIDDALALDTETLETLQSKFSKRIETKAKKRKAKEDFIDQENRNSNDMLKKYPYGLHIQNIKDEFESFLSRNNDRLTFPPLDPHGNKTVMKIAKHYNMKSSKIGKANHTSVVVEKIKKTKWSSPNYSLIDQLMRQRPVFMRIDIRRPREEQAAFERTKTIRGKFHVKEGEIVGQNAPEIGNENIGRRMLEKLGWKSGEGLGIQGNKGISEPIFAKIKKNRSGLRHSES---------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: * . *: : :*** * : : : . .. :* . **: . :. . . * * ::* : :. *: .:: :... : * . . :***.* : . *::* .:.** * :. :. *. ...*.. :: :.: . : . :.. : :.:*::: :: :. . .:* ..: *: .. * * ..: :.. * .: : : ... .:.::: : . : :::: . * . .. ..* :.: .*.. :**. :.* : :.* *. *: .: .: :. . .:.. ...: . . *: . . *. *:. **.*:... : .:: . .*. : ::. . * :: . : .:.:.:* :*:*. .: . . .* ::* *: . .**: : ::* : * . * :**:** * :.***.***:.:**..* *** :* :**:**: * : : ** .. . ", "identical_positions": 85, "similar_positions": 220, "identity": "10.87%" }, { "cls_id": "homologset.agr.RGD:1308866", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L9L9-1", "uniprot_id": "A0ABK0L9L9_RAT", "id": "A0ABK0L9L9-1", "name": "", "aln": "MPGSATAIRQERLKTTHSRTIPLVLFTINEEDELQKNGNSRRPKASDG---YKIQGKRPAPSRPTSTLSGQ--------TSNHSGNKPDPPPVLRVDDRQRLARERREEREKQLAARETVWLEREERARQHYERHLEARKKKLEDQRLKEERRRAAVEEKRRQRLEEDKERHEAVVRRTMERSQKPKQKYNRWSWGSPLHGSSSIHS--------------------------------GDPDRRSVSTMNLSKHVDPVISKRLSSSSATLLNSPDRAR-----------------------------------RLQLSPWESSVVSRLLTPTHSFLARSKSTAALSGDTAS--------CSPIT-TPFKTAHSRNPVDRPKLFITPPEGSARRRTIHGISSYKRERE--HIPFHVSPGVRRTLSPSNLKARSPAPARLWPPSKSMPHLPGTPRPASSLTPGPVRAA---ASSSSPGNIRPVKREVKVEPEKKDPEK---KVTNDPTIKGRVPLVKVEEGTVEEGTPVKP---PDP--------AVPAPTPATDPAPAP------PSPSSVSVGVIPKTSAGTTDPEEATRLLAEKRRLAREQREKEERERKEKEELERQKIEELARRVAEERS-RREEEARRLEAEQARKREELALRLAEEERERWEREEVERAQKQKEEE-ARAREEAEKARQEREKHFQKEEQERLERKKRLEEIMRRTRRTETADKKTTGQSNGDMVK------GVLAGETEVSA-LPGVN-SPGHVESAGSTHGVALQQSKVTIESSPDLEKQPNENGMSTQNENFEEIINLPVGSKASRLDVSN-----ENPEIPLKPILAFNDEGTLGPLPQVDGVQTQQTTEVI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88735-1", "uniprot_id": "MAP7_MOUSE", "id": "O88735-1", "name": "Ensconsin", "aln": "----------------------MAEQGAGGDGHRGGDGATHSDPASDG---YKVQEKRTAPSRPTSTVSGQ--------TSNHSGNKPDPPPVLRVDDRQRLARERREEREKQLAARETVWLEREERARQHYERHLEARKKKLEDQRLKEERRRAAVEEKRRQRLEEDKERHEAVVRRTMERSQKPRQKSNRWSWGSPLHGSSSIHS--------------------------------GDPDRRSVSTMNLSKHVDPVISKRLSSSSATLLNSPDRAR-----------------------------------RLQLSPWESSVVSRLLTPTHSFLARSKSTAALSGDTAS--------CSPII-MPFKAAHSRNPVDRPKLFVTPPEGSARRRTIHGLASHKREREREHVPFHVSPGARRTLSPSNLKARSPAPARLWLPSKSMPHLPGTPRPASSLPPGSVRAASAQAPSSSPGNIRPFKREVKVEPEKKDP---------LPAVKSRVPLVKVEEVTVEEGTPVKP---PEPAAPASAPIATPAPAPATDPAPVP------APSSTVTVGVVPKTSAGTTDPEEATRLLAEKRRLAREQREKEERERKEKEELERQKIEELARRVAEERS-RREEEARRLEEEQAREKEELALRLAEEERERWEREEVERVQKQKEEE-ARAREEAERARQEREKHFQKEEQERLERKKRLEEIMRRTRRTETADKKTTEQRNGDIAK------GVLTGEPEVPA-LPCMA-SSGNGESAESPHGVALQQSEVTTESSPDLEKQPNENGMSIQNENFEEVINLPVGSKASRLDVTN-----ENPEIPLKPILAFNDEGTLGPLPQVDGVQTQQTAEVI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14244-1", "uniprot_id": "MAP7_HUMAN", "id": "Q14244-1", "name": "Ensconsin", "aln": "----------------------MAELGAGGDGHRGGDGAVRSETAPDS---YKVQDKKNASSRPASAISGQ--------NNNHSGNKPDPPPVLRVDDRQRLARERREEREKQLAAREIVWLEREERARQHYEKHLEERKKRLEEQRQKEERRRAAVEEKRRQRLEEDKERHEAVVRRTMERSQKPKQKHNRWSWGGSLHGSPSIHS--------------------------------ADPDRRSVSTMNLSKYVDPVISKRLSSSSATLLNSPDRAR-----------------------------------RLQLSPWESSVVNRLLTPTHSFLARSKSTAALSGEAAS--------CSPII-MPYKAAHSRNSMDRPKLFVTPPEGSSRRRIIHGTASYKKERERENVLFLTS-GTRRAVSPSNPKARQPARSRLWLPSKSLPHLPGTPRPTSSLPPGSVKAAPAQVRPPSPGNIRPVKREVKVEPEKKDPEKEPQKVANEPSLKGRAPLVKVEEATVEERTPAEPEVGPAAPAMAPAPASAPAPASAPAPAPVPTPAMVSAPSSTVNASASVKTSAGTTDPEEATRLLAEKRRLAREQREKEERERREQEELERQKREELAQRVAEERTTRREEESRRLEAEQAREKEEQLQRQA-EERALREREEAERAQRQKEEE-ARVREEAERVRQEREKHFQREEQERLERKKRLEEIMKRTRRTEATDKKTSDQRNGDIAK------GALTGGTEVSA-LPCTTNAPGNGKPVGSPHVVTSHQSKVTVESTPDLEKQPNENGVSVQNENFEEIINLPIGSKPSRLDVTNS----ESPEIPLNPILAFDDEGTLGPLPQVDGVQTQQTAEVI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TG86-1", "uniprot_id": "A0AB32TG86_DANRE", "id": "A0AB32TG86-1", "name": "", "aln": "----MPAPLRTRRGACRSAVPSLSTIAEEEEGQRSRKRRRRGGGGSDY---LLRADEKSSWSRPDSSASGQYTYTIPSPTEIHTVTKPEP-LMLKNDERQRLARERREELDKQNAVRGSKWQEREERARQFHERQLEERKKRLEEQRMKEDKRRAAVEEKRRQKLEEEKVRYEAVIRRTMERSQRARPKSNRWSWGGTLSVSTSHNSGFDDCALFPLDLAGLEHYHGVFSLAHQQQMRSKYADRRSVSTMNLSKHTDPVISKRLSSSSATLLNSPDRALRKQTSFSSSCLLKKTLSKSQISREKTPQDKTAGMRRMPLTPWENTVISRLQTPTHSYLARSRSAMSLSGEAVTPVCPRSASCHPMSSMSFKSIQSR-SAERPMKAGLNLERPIRAGFIPPDGSNRRKIT-QNIMIDRKDKDNVRKSWSNLSYPTPSLS-LFTP-KRAPSPVGHRSRVTNPSPNRSSTAKPFQKTPNPKKSRSPPPPASIPLSHSNPSLS------PGNLRPSRPTSESLRVTAEREAAKKE-------------DVEPPKTEPEAPLTTTE-----PSSEASGSSPGGRPSAGTTDPEEASRLLAEKRRQAREQREREEEEKRQQEEAERRSREEMARRKAEERA-KREEEAQR-QAEEKRRKEEEEMRLE-EERAQREREEAERLQKQKEEEEARQKEEAERLRLEREKHFQKEEAERMERKKRLEEIMKRTRR---SDQKTTPQRNGDVSQQSGQDPGSVSGGPSVSVSDPLASETLETVQSDSNGHTGPSYITPVLPTSGHSMSALLRENGT--INETFEQVIEVPLANKLSRQDGDGEELDREEEEERKRPFLAFRENGSTHNVSELNEEPTL------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3AIT0-1", "uniprot_id": "A0A8M3AIT0_DANRE", "id": "A0A8M3AIT0-1", "name": "", "aln": "MPAHLSLAEQEREWRKTGRTVEMGFKAISEKGQLKTCDTAKKQRDSRSEVKTTVLEHKRKACTPLHSKPPQ------MKINSQNGNNAES-NVLKVDERLRMARERREAYQKQIALRERGWLAREERAKQIYEKHLEERRKKLEEQRQREERRRTAVEEKRRQRLKEDRERYESVVRKTIEKSLKAKQKPG---------------------------------------------------------------HCSRKVTK----------NDNKNAK-----------------------------------RRSLSQWEIDLVRRLQTPTVSYLARSRSAVCLSRDTVVHVCRRSVSCHTMN--SSTNLHCGKVPNRPGGSNVTIRRTTNRELVAKDNTEGQDLK--------KLQLQRSTTTTEIKP------------KQDTEPPENTVLATSWLQNRSHVRNATLKQDS---LPPLPEEEDLEPE--------------PEPSSSHTKSEKTRCLKENSLQLNT--------------ASNGPLHPLQVSQIP------NGPSQIADSAQVRPTSWTKDPEEASRILAEKRRQARLQKEKEEEERRQKEETERKRREELARRRAEERA-RQEAEALKLEEEKRKREQEEQLKAA-AENARIQKEEENRLQQQREEE-ARQSVLAEQQRVEREIRFQKEKAERQERKKRLEQIMKRTRKTDSVDKKAASVKDN-------------------------------------------------------------------LPCENVNPVIRLAGPGKTPKLELRD--------EEDMLPTVAFKERRSFRSLSGLDEIQTHQQTEVI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ... : . .: . * : . * . :. .:.:. :*: *:* *:****** :** * * * *****:* :*::** *:*:**:** :*::**:********:*:*:: *:*:*:*:*:*:* :.: * . : . ::* *. ..* * *: ** :: ** *** *:****:*: .** ::. * .: . . :. :** . . . : : :. . . : :: . * . .:. . . . . .: . . : . *. : . . .. . :.:: *.*****:*:****** ** *:*:**.*::::** **: **:*:* ****: ::* *: : : *: :..:* : *. ::** :* *:*:*** ** **: * *** :**:*: ** *******:**:***: *:*:: :. *..: :*.:. .* .: : . * * :** :. : :. :: * ", "identical_positions": 158, "similar_positions": 174, "identity": "18.12%" }, { "cls_id": "homologset.agr.RGD:1308867", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D898-1", "uniprot_id": "ARP5L_MOUSE", "id": "Q9D898-1", "name": "Actin-related protein 2/3 complex subunit 5-like protein", "aln": "MARNTLSSRFRRVDIDEFDENKFVDEHE------EAAAAAGEPGPDPCEVDGLLRQGDMLRAFHAALRNSPINTKNQAVKERAQGVVLKVLTNFKSSEIEQAVQSLDRNG-IDLLMKYIYKGFEKPT-ENSSAVLLQWHEKALAVGGLGSIIRVLTARKTV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A1L108-1", "uniprot_id": "ARP5L_RAT", "id": "A1L108-1", "name": "Actin-related protein 2/3 complex subunit 5-like protein", "aln": "MARNTLSSRFRRVDIDEFDENKFVDEHE------EAAAASGEPGPDPCEVDGLLRQGDMLRAFHAALRNSPINTKNQAVKERAQGIVLKVLTNFKSSEIEQAVQSLDRNG-IDLLMKYIYKGFEKPT-ENSSAVLLQWHEKALAVGGLGSIIRVLTARKTV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BPX5-1", "uniprot_id": "ARP5L_HUMAN", "id": "Q9BPX5-1", "name": "Actin-related protein 2/3 complex subunit 5-like protein", "aln": "MARNTLSSRFRRVDIDEFDENKFVDEQE------EAAAAAAEPGPDPSEVDGLLRQGDMLRAFHAALRNSPVNTKNQAVKERAQGVVLKVLTNFKSSEIEQAVQSLDRNG-VDLLMKYIYKGFEKPT-ENSSAVLLQWHEKALAVGGLGSIIRVLTARKTV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VQD8-1", "uniprot_id": "Q9VQD8_DROME", "id": "Q9VQD8-1", "name": "Actin-related protein 2/3 complex subunit 5", "aln": "MAKNTSSNAFRKIDVDQYNEDNFREDDG------VESAAAG---PDESEITTLLTQGKSVEALLSALQNAPLRCKNQNVKDHALNITLRVLLSIKSTQMDQAIDTLDQNDLIDVLMKYIYRGFEIPS-EGSSGHLLQWHEKAFAKGGVGCIVRVLSDTNRA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40518-1", "uniprot_id": "ARPC5_YEAST", "id": "P40518-1", "name": "Actin-related protein 2/3 complex subunit 5", "aln": "-----MEADWRRIDIDAFDPESGRLTAADLVPPYETTVTLQELQPRMNQLRSLATSGDSLGAVQLLTTDPPYSADAP-TKEQYFKSVLEALTQVRQADIGNVIKNLSDSQ-RDVLVKYLYKGMSVPQGQKQGGVLLAWLERITQVSGVTPIVHYISDRRTV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :*::*:* :: :. :.: * :: * .*. : *. :.* . .*:: .*..* ..:.::: :.:..*. . *:*:**:*:*:. * : ... ** * *: .*: *:: :: . .", "identical_positions": 25, "similar_positions": 60, "identity": "15.53%" }, { "cls_id": "homologset.agr.RGD:1308868", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9BRA2-1", "uniprot_id": "TXD17_HUMAN", "id": "Q9BRA2-1", "name": "Thioredoxin domain-containing protein 17", "aln": "MARYEEVSVSGFEEFHRAVEQHNGKTIFAYFTGSKDAGGKSWCPDCVQAEPVVREGLKHISEGCVFIYCQVGEKPYWKDPNNDFRKNLKVTAVPTLLKYGTPQKLVESECLQANLVEMLFSED", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0M2Q2-1", "uniprot_id": "A0ABK0M2Q2_RAT", "id": "A0ABK0M2Q2-1", "name": "Thioredoxin domain-containing protein 17", "aln": "MATFEEVSVLGFEEFDKAVKEHQGKTIFAFFSGSKDTEGKSWCPDCVEAEPIIREGLKHVTEDCVFIYCQVGDKPYWKDPNNDFRQKLKITAVPTLLKYGTPQKLVESECRQSNLVEMIFSED", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** :***** *****.:**::*:******:*:****: *********:***::******::*.*********:************::**:******************** *:*****:****", "identical_positions": 98, "similar_positions": 21, "identity": "79.67%" }, { "cls_id": "homologset.agr.RGD:1308869", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZY40-1", "uniprot_id": "A0A8I5ZY40_RAT", "id": "A0A8I5ZY40-1", "name": "A-kinase anchor protein 10, mitochondrial", "aln": "MRGAGPSPRHSPRALRPDPGPAMSFFRRKVKGKEQEKNLDVKSIKASIAVHSPQKSTKNHALLEAAGPSHVAINAISANMDSFSSSRTATLKKQPSHMEAAHFGDLGRSCLDYQTQETKSSLSKTLEQVLRDSVVLPYFLQFMELRRMEHLVKFWLEAESFHSTTWSRIRAHSLNTVKQSSLAEPVSPSKKQETTASFVTESLDRRLGDSSSAPLLLTQSEGTDLSSRTQNTQNHLLLSQECHSTHSLHHEVARTGTHQISTDSQESSSRLAVASRNSCSSPLRELSEKLMKSIEQDAVNTFTKYISPDAAKPIPITEAMRNDIIAKICGEDGQ-----VDPNCFVLAQAVVFSAMEQEHFSEFLRSHHFCKYQIEVLTSGTVYLADILFCESALFYFSEYMEKEDAVNILQFWLAADNFQSQLAAKKG-QYDGQEAQNDAMILYDKYFSLQATHPLGFDDVVRLEIESNICREGGPLPNCFTTPLRQAWTTMEKVFLPGFLSSNLYYKYLNDLIHSVRG---DEFLGGNVSLAAHG------------SVCLPEESHSGGSDGSTAQSSVKKASIKILKNFDEAIVVDAASLDPESLYQRTYAGKMSFGRVSDLGQFIRESEPEPDVKKSK--------GFMFSQAMKKWVQGNTDEAQEELAWKIAKMIVSDVMQQAHHDQPLEKSTKL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88845-1", "uniprot_id": "AKA10_MOUSE", "id": "O88845-1", "name": "A-kinase anchor protein 10, mitochondrial", "aln": "MRGAGPSPRHSPRALRPDPGPAMSFFRRKVKGKEQEKTLDVKSTKASVAVHSPQKSTKNHALLEAAGPSHVAINAISANMDSFSSSRTATLKKQPSHMEAAHFGDLGRSCLDYQTQETKSSLSKTLEQVLRDTVVLPYFLQFMELRRMEHLVKFWLEAESFHSTTWSRIRAHSLNTVKQSSLAEPVSPSKRHETPASSVTEALDRRLGDSSSAPLLVTQSEGTDLSSRTQNPQNHLLLSQEGHSARSLHREVARTGSHQIPTDSQDSSSRLAVGSRNSCSSPLRELSEKLMKSIEQDAVNTFTKYISPDAAKPIPITEAMRNDIIAKICGEDGQ-----VDPNCFVLAQAVVFSAMEQEHFSEFLRSHHFCKYQIEVLTSGTVYLADILFCESALFYFSEYMEKEDAVNILQFWLAADNFQSQLAAKKG-QYDGQEAQNDAMILYDKYFSLQATHPLGFDDVVRLEIESNICREGGPLPNCFTTPLRQAWTTMEKVFLPGFLSSNLYYKYLNDLIHSVRG---DEFLGGNVSLAAHG------------SVCLPEESHSGGSDGSTAQSSVKKASIKILKNFDEAIIVDAASLDPESLYQRTYAGKMSFGRVSDLGQFIRESEPEPDVKKSK--------GFMFSQAMKKWVQGNTDEAQEELAWKIAKMIVSDVMQQAHHDQPLEKSTKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43572-1", "uniprot_id": "AKA10_HUMAN", "id": "O43572-1", "name": "A-kinase anchor protein 10, mitochondrial", "aln": "MRGAGPSPRQSPRTLRPDPGPAMSFFRRKVKGKEQEKTSDVKSIKASISVHSPQKSTKNHALLEAAGPSHVAINAISANMDSFSSSRTATLKKQPSHMEAAHFGDLGRSCLDYQTQETKSSLSKTLEQVLHDTIVLPYFIQFMELRRMEHLVKFWLEAESFHSTTWSRIRAHSLNTVKQSSLAEPVSPSKKHETTASFLTDSLDKRLEDSGSAQLFMTHSEGIDLNNRTNSTQNHLLLSQECDSAHSLRLEMARAGTHQVSMETQESSSTLTVASRNSPASPLKELSGKLMKSIEQDAVNTFTKYISPDAAKPIPITEAMRNDIIARICGEDGQ-----VDPNCFVLAQSIVFSAMEQEHFSEFLRSHHFCKYQIEVLTSGTVYLADILFCESALFYFSEYMEKEDAVNILQFWLAADNFQSQLAAKKG-QYDGQEAQNDAMILYDKYFSLQATHPLGFDDVVRLEIESNICREGGPLPNCFTTPLRQAWTTMEKVFLPGFLSSNLYYKYLNDLIHSVRG---DEFLGGNVSLTAPG------------SVGPPDESHPGSSDSSASQSSVKKASIKILKNFDEAIIVDAASLDPESLYQRTYAGKMTFGRVSDLGQFIRESEPEPDVRKSK--------GSMFSQAMKKWVQGNTDEAQEELAWKIAKMIVSDIMQQAQYDQPLEKSTKL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V3I3-1", "uniprot_id": "Q9V3I3_DROME", "id": "Q9V3I3-1", "name": "", "aln": "--MLNYIKRHASRRRSSQDATDAICGQMPAYDVDTN---DVAGAGDAANAHKRHSLRSTTSFCDEVFLEAEEEGGVGTTGGGGGGGGGGGGGGAPSDGISLASNDD--------IFTYNSRLSMNLASIVNDPNCLSYFVQYLDTRQALPLIKFYLDIENFKRAALTQEKE------------EPEEPPRK------------------------------AIEQSSPHKDDKDVPELKTLCD--LSMRKPLTDDEKSRIYAETNKQLNRQKSGTDS-------VLNAELSRASISDAIAIYQKYLIVNASLQVELPIVILAHISLLLCGRDKSECSKPIPASCFDEAREFVLEQLERDHVQGFLQSGYYSTYCLELIEGGSVNIYDVLNSELALFYFTEYLEQRQERECLEFWITAINFRKSFACGEEKEEDRKAAQSDAMIIYDKYFSLQSECRLWMSQKLRLRVEQAICAPN-EQWQAFDLALLVTAKYLEQKYFADFLKSHIFDNYVNELKVKRDNSTTHPNLQHTLSLRRAGKSSNGQQQRHRKTLSMSDCTHISQHN-TLLASMDQAPSKTALNHQSGNLNIDARQLTNPQLLWQRPVGALKFGFVNSLGRYERDFEAVDAVALKSQPWSLSVSGSKLKNAMRKLVNLPEDNVQEEIAWQVAEMIVRDVTSVTLSGKTPPLA---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08760-1", "uniprot_id": "RAX1_YEAST", "id": "Q08760-1", "name": "Bud site selection protein RAX1", "aln": "------MKEELSKVSSMQNFEMIQRERLPTLY--------------EVLIQRTSQPVDLWTFYTFLSQFPYAINYLDFWVD----------------------------------LMTHTRLCKNYIELVRKS--LINFPQEQQQNGSTSTATFDLLNALIEEGHLD-----------------PEAPDKLLE------------------------------NSGPDVPFSPKLNELLGDWKHQSGIGQEALRNEDVALIVDEIMKRRSQQDGKPQ--------ITTKQLLHSAVGLCNTYLVSPEQSERYLSNIPMETRNRIIESVQIERKY------DIEIFDDLKNLTYQFLEMDCFPKFLSR-------------------------------VALHNIHDEISDWRFHSVGVTNEKSNRSRGQTHISRSPFSNHTSISRIGFGLLWLGIGFWIGYVLIFLAYS----------RAIRVVTVVPFTLGCYCIVCGMYQVDIVYSWFGVTQRLLHR-------------------------------------HKNAGNDEGDASSDTDHVPMILAVFGGRRRLTRIEHPFTRQLLRKRGLWCLLLVVGATAAFTVIFSCVPGRRV-------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. .: : : . : . . :: . :. . :: *. . .::... * * * : . .* * :. * * : : . . * . .: : : . .. . :. : . : . :. * : . . * : .. . :* : . ** : .: . .* .. . ... . . . . ...: * : * : :. : : . ..: . . . .: . .: .:.. * . : * * . : . : : *. . : . ", "identical_positions": 21, "similar_positions": 114, "identity": "3.04%" }, { "cls_id": "homologset.agr.RGD:1308871", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "B5DFC8-1", "uniprot_id": "EIF3C_RAT", "id": "B5DFC8-1", "name": "Eukaryotic translation initiation factor 3 subunit C", "aln": "MSRFFTTGSDSESESSLSGEELVTKPVSGNYGKQPLLLSEDEEDTKRVVRSAKDKRFEELTNLIRTIRNAMKIRDVTKCLEEFELLGKAYGKAKSIVDKEG---VPRFYVRILADLEDYLNELWEDKEGKKKMNKNNAKALSTLRQKIRKYNRDFESHITNYKQNPEQSADEDAEKNEEDSEGSSDEDEDDDGVSGTAFLKKK---PDS-SGESRKFHKKMEDDDEDSEDSEDEE-WDTSSTSSDSDSEEEEGKQTVLASKFLKKAPTTEEDKKAAEKKREDKAKKKHDRKSKRMDEEEE-DNEGGEWERVRGGVPLVKEKPKMFAKGTEITHAVVIKKLNEILQVRGKKGTDRATQIELLQLLVQIASENNLGVGVIVKIKFNIIASLYDYNPNLATYMKPEMWQMCLDCINELMDTLVAHSNIFVGENILE-----ESENLHNFDQPLRVRGCILTLVERMDEEFTKIMQNTDPHSQEYVEHLKDEAQVCAIIERVQRYLEEKGTTEE-----ICQIYLRRILHTYYKFD-----YKAHQRQLTPPEGSSKSEQDQAENEGEDSAVLMERLCKYIYAKDRTDRIRTCAILCHIYHHALHSRWYQARDLMLMSHLQDNIQHADPPVQILYNRTMVQLGICAFRQGLTKDAHNALLDIQSSGRAKELLGQGLLLRSLQERNQEQEKVERRRQ-VPFHLHINLELLECVYLVSAMLLEIPYMAAHESDARRRMIS---KQFHHQLRVGERQPLLGPPESMREHVVAASKAMKMGDWKTCHSFIINEKMNGKVWDLFPEADKVRTMLVRKIQEESLRTYLFTYSSVYDSISMETLSDMFELDLPTVHSIISKMIINEELMASLDQPTQTVVMHRTEPTAQQNLALQLAEKLGSLVENNERVFDHKQG---------------------TYGGYF----RDQKDGYRKNEGYMR---RGGYRQQQ----------SQTAY--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R1B4-1", "uniprot_id": "EIF3C_MOUSE", "id": "Q8R1B4-1", "name": "Eukaryotic translation initiation factor 3 subunit C", "aln": "MSRFFTTGSDSESESSLSGEELVTKPVSGNYGKQPLLLSEDEEDTKRVVRSAKDKRFEELTNLIRTIRNAMKIRDVTKCLEEFELLGKAYGKAKSIVDKEG---VPRFYIRILADLEDYLNELWEDKEGKKKMNKNNAKALSTLRQKIRKYNRDFESHITNYKQNPEQSADEDAEKNEEDSEGSSDEDEDEDGVGNTTFLKKK---QES-SGESRKFHKKMEDDDEDSEDSEDEE-WDTSSTSSDSDSEEEEGKQTVLASKFLKKAPTTEEDKKAAEKKREDKAKKKHDRKSKRLDEEEE-DNEGGEWERVRGGVPLVKEKPKMFAKGTEITHAVVIKKLNEILQVRGKKGTDRATQIELLQLLVQIAAENNLGVGVIVKIKFNIIASLYDYNPNLATYMKPEMWQMCLDCINELMDTLVAHSNIFVGENILE-----ESENLHNFDQPLRVRGCILTLVERMDEEFTKIMQNTDPHSQEYVEHLKDEAQVCAIIERVQRYLEEKGTTEE-----ICQIYLRRILHTYYKFD-----YKAHQRQLTPPEGSSKSEQDQAENEGEDSAVLMERLCKYIYAKDRTDRIRTCAILCHIYHHALHSRWYQARDLMLMSHLQDNIQHADPPVQILYNRTMVQLGICAFRQGLTKDAHNALLDIQSSGRAKELLGQGLLLRSLQERNQEQEKVERRRQ-VPFHLHINLELLECVYLVSAMLLEIPYMAAHESDARRRMIS---KQFHHQLRVGERQPLLGPPESMREHVVAASKAMKMGDWKTCHSFIINEKMNGKVWDLFPEADKVRTMLVRKIQEESLRTYLFTYSSVYDSISMETLSDMFELDLPTVHSIISKMIINEELMASLDQPTQTVVMHRTEPTAQQNLALQLAEKLGSLVENNERVFDHKQG---------------------TYGGYF----RDQKDGYRKNEGYMR---RGGYRQQQ----------SQTAY--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99613-1", "uniprot_id": "EIF3C_HUMAN", "id": "Q99613-1", "name": "Eukaryotic translation initiation factor 3 subunit C", "aln": "MSRFFTTGSDSESESSLSGEELVTKPVGGNYGKQPLLLSEDEEDTKRVVRSAKDKRFEELTNLIRTIRNAMKIRDVTKCLEEFELLGKAYGKAKSIVDKEG---VPRFYIRILADLEDYLNELWEDKEGKKKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEGSSDEDEDEDGVSAATFLKKK---SEAPSGESRKFLKKMDDEDEDSEDSEDDEDWDTGSTSSDSDSEEEEGKQTALASRFLKKAPTTDEDKKAAEKKREDKAKKKHDRKSKRLDEEEE-DNEGGEWERVRGGVPLVKEKPKMFAKGTEITHAVVIKKLNEILQARGKKGTDRAAQIELLQLLVQIAAENNLGEGVIVKIKFNIIASLYDYNPNLATYMKPEMWGKCLDCINELMDILFANPNIFVGENILE-----ESENLHNADQPLRVRGCILTLVERMDEEFTKIMQNTDPHSQEYVEHLKDEAQVCAIIERVQRYLEEKGTTEE-----VCRIYLLRILHTYYKFD-----YKAHQRQLTPPEGSSKSEQDQAENEGEDSAVLMERLCKYIYAKDRTDRIRTCAILCHIYHHALHSRWYQARDLMLMSHLQDNIQHADPPVQILYNRTMVQLGICAFRQGLTKDAHNALLDIQSSGRAKELLGQGLLLRSLQERNQEQEKVERRRQ-VPFHLHINLELLECVYLVSAMLLEIPYMAAHESDARRRMIS---KQFHHQLRVGERQPLLGPPESMREHVVAASKAMKMGDWKTCHSFIINEKMNGKVWDLFPEADKVRTMLVRKIQEESLRTYLFTYSSVYDSISMETLSDMFELDLPTVHSIISKMIINEELMASLDQPTQTVVMHRTEPTAQQNLALQLAEKLGSLVENNERVFDHKQG---------------------TYGGYF----RDQKDGYRKNEGYMR---RGGYRQQQ----------SQTAY--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B5ME19-1", "uniprot_id": "EIFCL_HUMAN", "id": "B5ME19-1", "name": "Eukaryotic translation initiation factor 3 subunit C-like protein", "aln": "MSRFFTTGSDSESESSLSGEELVTKPVGGNYGKQPLLLSEDEEDTKRVVRSAKDKRFEELTNLIRTIRNAMKIRDVTKCLEEFELLGKAYGKAKSIVDKEG---VPRFYIRILADLEDYLNELWEDKEGKKKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEGSSDEDEDEDGVSAATFLKKK---SEAPSGESRKFLKKMDDEDEDSEDSEDDEDWDTGSTSSDSDSEEEEGKQTALASRFLKKAPTTDEDKKAAEKKREDKAKKKHDRKSKRLDEEEEEDNEGGEWERVRGGVPLVKEKPKMFAKGTEITHAVVIKKLNEILQARGKKGTDRAAQIELLQLLVQIAAENNLGEGVIVKIKFNIIASLYDYNPNLATYMKPEMWGKCLDCINELMDILFANPNIFVGENILE-----ESENLHNADQPLRVRGCILTLVERMDEEFTKIMQNTDPHSQEYVEHLKDEAQVCAIIERVQRYLEEKGTTEE-----VCRIYLLRILHTYYKFD-----YKAHQRQLTPPEGSSKSEQDQAENEGEDSAVLMERLCKYIYAKDRTDRIRTCAILCHIYHHALHSRWYQARDLMLMSHLQDNIQHADPPVQILYNRTMVQLGICAFRQGLTKDAHNALLDIQSSGRAKELLGQGLLLRSLQERNQEQEKVERRRQ-VPFHLHINLELLECVYLVSAMLLEIPYMAAHESDARRRMIS---KQFHHQLRVGERQPLLGPPESMREHVVAASKAMKMGDWKTCHSFIINEKMNGKVWDLFPEADKVRTMLVRKIQEESLRTYLFTYSSVYDSISMETLSDMFELDLPTVHSIISKMIINEELMASLDQPTQTVVMHRTEPTAQQNLALQLAEKLGSLVENNERVFDHKQG---------------------TYGGYF----RDQKDGYRKNEGYMR---RGGYRQQQ----------SQTAY--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PFQ2-1", "uniprot_id": "EIF3C_DANRE", "id": "Q6PFQ2-1", "name": "Eukaryotic translation initiation factor 3 subunit C", "aln": "MSRFFATGSDSESEESSSADEITPKAAGTTLRQQALLLSDDEEDTKRVVRSAKDKRFEELTNLIKTIRNAIKIRGISKCLEEFEQLCRAFVKSKTIVDKEG---VPKFYIRLLADLEDYLNQLWEDKEGKKKMNKNNAKALSTLRQKIRKYNRDFETEIASYKENPEQSADEEEEKDDIGSGSSESDDDDDDDITAKSFMKKKPQEEEKKAPEASKFLKGAADEESESDDDEDSEDWASDSVGSDSESEDNDGTAASLAVVFLKK----DVGEKASDRKKDDRRRRHKKKERIEEEAEEEGEAEEGGWEKVKGGVPLVKEKPKMFAKGTEINTGVVVKKLSEILQARGKKGTDRAAQIELLHALAGIAAENNLGEGILVKIKFNIIASLYDYNPNLAAFMKADMWKKCLDCIDELLDILFNNNNIFIGENIAE-----DSENLAISDQPFRVRGCILTLVERMDEEFTKIMQNTDPHSQEYVDNLKDEGRVCGIIDRLLQYLETKGSTEE-----VCRVYLRRIMHTYYKFD-----YKAHRRSLG-LQGETKSEQDQEESEGDDSAIIMDRLCKFIYAKDRTDRIRTCAILCHIYHHALHSRWYQARDLMLMSHLQDNIQHADPPVQILYNRTMVQLGICAFRQGMIKDAHNALLDIQSSGRAKELLGQGLLMRNMQERNAEQEKIEKRRQ-VPFHMHINLELLECVYLVSAMLLEIPYMAAHEFDARRRMIS---KQFHHQLRVGERQPLLGPPESMREHVVAASKAMKMGDWRTCHSFIINEKMNSKVWDLFPEAKCVREMLVRKIQEESLRTYLFTYSSVYDSISMETLSEMFELELPTVHSIISKMIINEELMASLDQPTQTVVMHRTEPTSLQNMALQLAEKLGGLVENNERVFDLKQG---------------------VYGGYFN---RDQKGGYQQKQGYQRGDQKGGYQQKQNYQRGGYRNQNQSSY--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1ZAX1-1", "uniprot_id": "EIF3C_DROME", "id": "A1ZAX1-1", "name": "Eukaryotic translation initiation factor 3 subunit C", "aln": "MSRFFANGSESESES--SEEEIQATNFN---KASAFQFSDDEEEVKRVVRSTKEKRYENLTSIIKTIRNHKKIKDIPNTLSSFEDLTRAYQKALPVISKEENGITPRFYIRCLAELEDFINEVWEDREGRKNLSKNNSKSLGTLRQKVRKYIKDFEDDLSRFREAPDQESEAEDEVVALESDGGDAGDDSDAGVKPTEAVPKA---------VKSAPAKAAPADDDDSDDS---IDWDSDSE-SETESSDDENQYQNMRERFLKR---TTEKEEKDDDKRKDKRKEQKTKIRKRAEDDED-----GEWETVVKGH--VVEKPKMFEKDAEIDVPLVLAKLLEIMSARGKKRTDRRLQIDLLFELRDISDQHNLGTAVSVKIHFNIISAIYDYNQKISEPMKLEHWALLLEVMQSMMKLLLANADIIMSESVAE-----EHEEYATS--PFYVRGCPLAAVERLDDEFVKLLKECDPHSNDYVSRLKDEVNVVKTIELVLQYFERSGTNNE-----RCRIYLRKIEHLYYKFD-----PEVLKKKRGELPATTSTSVD-----------VMDKLCKFIYAKDDTDRIRTRAILAHIYHHAMHDNWFQARDLVLMSHLQDNIDAADPATRILYNRMMANLGLCAFRQGNVKDAHHCLVDLMVTGKPKELLAQGLLPQRQHERSAEQEKIEKQRQ-MPFHMHINLELLECVYLVSAMLLEIPYIAAHEFDARRRMIS---KTFYQQLRSSERQSLVGPPESMREHVVAAAKAMRCGNWQACANFIVNKKMNTKVWDLFYESDRVREMLTKFIKEESLRTYLFTYSNVYTSISIPSLAQMYELPVPKVHSIISKMIINEELMASLDDPSETVGMHRSEPSRLQALAMQFVDKVTNLVDVNEKVFDMKQGNFFQRGNMGNRGDRGYNRNQNNQGGNWLGQRRDRNNRNRNQRGHHKNNQDRQQQQQQ---------QVQTIDEE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32497-1", "uniprot_id": "EIF3C_YEAST", "id": "P32497-1", "name": "Eukaryotic translation initiation factor 3 subunit C", "aln": "MSRFFSSNYEYDVASSSSEEDLLSSSEEDLLSSSSSESELDQESDDSFFNESESE----------------SEADVDSDDSDAKPYGPDWFKKSEFRKQGG-------------GSNKFLKSSNYDSSDEESDEEDGKKVVKSAKEKLLDEMQDVYNKIS----QAENSDDWLTISNEFDLISRLLVRAQQQNWGTPNIFIKV---------------------------------------VAQVEDAVNNTQQADLKNKAVARAYNTTKQRVKKVSRENEDSMAKFRNDPESFDKEPT-----ADLDISANGFTISSSQ-----GNDQAVQEDFFTRLQTIIDSRGKKTVNQQSLISTLEELLTVAEKP----YEFIMAYLTLIPSRFDASANLS-YQPIDQWKSSFNDISKLLSILDQTIDTYQVNEFADPIDFIEDEPKEDSDGVKRILGSIFSFVERLDDEFMKSLLNIDPHSSDYLIRLRDEQSIYNLILRTQLYFEATLKDEHDLERALTRPFVKRLDHIYYKSENLIKIMETAAWNIIPAQFKSKFTSKDQLDSADYVDNLIDGLS-TILSKQNNIAVQKRAILYNIYYTALNKDFQTAKDMLLTSQVQTNINQFDSSLQILFNRVVVQLGLSAFKLCLIEECHQILNDLLSSSHLREILGQQSLHRISLNSSNNASADERARQCLPYHQHINLDLIDVVFLTCSLLIEIPRMTAFYSGIKVKRIPYSPKSIRRSLEHYDKLSFQGPPETLRDYVLFAAKSMQKGNWRDSVKYLR----EIKSWALLPNMETVLNSLTERVQVESLKTYFFSFKRFYSSFSVAKLAELFDLPENKVVEVLQSVIAELEIPAKLNDEKTIFVVEKGDEITKLEEAMVKLNKEYKIAKERLNPPSNRR---------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****:.. : : . * ::: .. .. . *:*. . ....::.: . .: . .. : : * . .: :.:::. * ...:. .::. * : : ::*: . :*. .:: .::. : . .: . . * :: :. :: : : : . :..: : . : : . : * .: . : .. :* *:. **** .:: *. * * :: : : :.:*.: :* . ::: : * :: :..::. * : :.. : : * : *. :: ***:*:** * : : ****.:*: .*:** : * *:* . . :. : :: :: * *** : :. . :. . ::: *. * :*: . ::. *** :**: *::. : *:*::* *::* **: *.. :**:** :.:**:.**: ::.*: * *: :.: :*:*.* * : : . : . *: ** :*:* ****:*:: *:*..::*:*** ::*. . : : *. * : :.*. :: .: ****::*::*: *:*:*: *:*: . .:: : * * *: : . * *.. :: ***:**:*::. .* *:*: .*:::::* .* .::..:* : *: *.*:: . . :.: : *: :* :.. . . . :: ", "identical_positions": 138, "similar_positions": 304, "identity": "14.1%" }, { "cls_id": "homologset.agr.RGD:1308872", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "B1WC58-1", "uniprot_id": "CTIP_RAT", "id": "B1WC58-1", "name": "DNA endonuclease RBBP8", "aln": "MSISGSSCGSPNSTDISSDFKELWTKLKEYHDKEVQGLQIKVTKLKKERILDAQRLEEFFTKNQQLRDQQKVLQETIKILEDRLRAGLCDRCAVTEEHMHKKQQEFENIRQQNLRLITELMNEKSALQEENKKLSEQLQQKMESGQQDQVAELECEENIIPDSPITSFSFSGINRLRRKENLHVRYVEQTHTKLEHSACTSELRKFSKGSTPAPVNSEEHEILVADTCDQSHSPLSKICGTSSYPADKLSSNLDAVVAETLGLDGQEESEPQGPVSPLGNELYHCLKEDHKKQPFMESAIRNEDNVRFSDSASKAPPRE-LTTRGSSPVFGPTSTVKTHLGLKTSFSPSLLDSGKKNLLSTAPFSSISVSRSEKVRSKSEDNALFTQQSAGSEVKVISQSFPSKQILTSKNVSDSVDEQGGADHMKDAVSDKHLVPLKSLGGKASKRKRTEEEGEHAVHCPQTCFDKENALPFPMENQFPVNGDHVMDKPLDLSDRFAANQRQEKNHGDETCKHKLKQVTIYEALKPVPKGSSSGRKALSGACTLAQDSAETYCLQQ-RTLQCSSKFSPDHNTQLQIKEENPVFKTPPRSQESLETENLFGDVKGIGSLVPIKVKGRSAHGGCELASVLQLNPCRVAKTKSLPSNHDMSFENIQWSVDPGADLSQYKMDVTVIDTKDSSHSRLGGETVDMDCTLVSETMLLKMKKQEQR-EKSPNGDIKMNDSLEDMFDRTTHEEYESCLADNFSQVPDEEE-LSDTTKK-PNIHGDKQDGIKQKAFVEPYFKDKERETSIQNFPHIEVVRKKEERRKLLGHTCKECEIYYADLPAEEREKKLASCSRHRFRYIPTNTPENFWEVGFPSTQTCLERGYIKEDLDPCPRPKRRQPYNAVFSPKGKEQRT--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80YR6-1", "uniprot_id": "CTIP_MOUSE", "id": "Q80YR6-1", "name": "DNA endonuclease RBBP8", "aln": "MSISGSGCGSPNSADASNDFKELWTKLKEYHDKEVQGLQVKVTKLKKERILDAQRLEEFFTKNQQLRDQQKVLQETIKILEDRLRAGLCDRCAVTEEHMHKKQQEFENIRQQNLKLITELMNEKNTLQEENKKLSEQLQQKMENGQQDQVAELACEENIIPDSPVTSFSFSGINRLRKKENLHVRYVEQTHTKLERSLCTNELRKISKDSAPAPVNSEEHEILVADTCDQNHSPLSKICETSSYPTDKTSFNLDTVVAETLGLNGQEESEPQGPMSPLGSELYHCLKEDHKKHPFMESARSKEDSLRFSDSASKTPPQE-FTTRASSPVFGATSTVKAHLGLNTSFSPSLLDIGKKNLLKTAPFSNIAVSRSEKVRSKSEDNALFTQHSLGSEVKVISQSFSSKQILTNKTVSDSVDEQCSADHMNTTVADKYLVPLKSLGGKASKRKRTEEESEHAVKCPQACFDKENALPFPMENQFSMNGDHVMDKPLDLSDRFAATQRQEKNHGNETSKNKLKQATIYEALKPIPKGSSSGRKALSGDCMPAKDSWETYCLQP-RSLQSSSKFSPDQKTPLQIKEENPVFKTPPCSQESLETENLFGDVKGTGSLVPTKVKSRAVHGGCELASVLQLNPCRVAKTKALPSNQDTSFENIQWSVDPGADLSQYKMDVTVIDTKDSSHSRLGGETVDMDCTLVSETVLLKMKKQEQK-ERSPNGDIKMNDSLEDMFDRTTHEEYESCLADSFSQVPDEEE-LPDTTKK-TNIPADKQDGVKQKAFVGPYFKDKERETSIQNFPHIEVVRKKEERRKLLGHTCKECEIYYADLPAEEREKKLASCSRHRFRYIPPNTPENFWEVGFPSTQTCLERGYIKEDLDLSPRPKRRQPYNAVFSPKGKEQRT--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99708-1", "uniprot_id": "CTIP_HUMAN", "id": "Q99708-1", "name": "DNA endonuclease RBBP8", "aln": "MNISGSSCGSPNSADTSSDFKDLWTKLKECHDREVQGLQVKVTKLKQERILDAQRLEEFFTKNQQLREQQKVLHETIKVLEDRLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQLQQKIENDQQHQAAELECEEDVIPDSPITAFSFSGVNRLRRKENPHVRYIEQTHTKLEHSVCANEMRKVSKSSTHPQHNPNENEILVADTYDQSQSPMAKAHGTSSYTPDKSSFNLATVVAETLGLGVQEESETQGPMSPLGDELYHCLEGNHKKQPFEESTRNTEDSLRFSDSTSKTPPQEELPTRVSSPVFGATSSIKSGLDLNTSLSPSLLQPGKKKHLKTLPFSNTCISRLEKTRSKSEDSALFTHHSLGSEVNKIIIQSSNKQILINKNISESLGEQNRTEYGKDSNTDKHLEPLKSLGGRTSKRKKTEEESEHEVSCPQASFDKENAFPFPMDNQFSMNGDCVMDKPLDLSDRFSAIQRQEKSQGSETSKNKFRQVTLYEALKTIPKGFSSSRKASDGNCTLPKDSPGEPCSQECIILQPLNKCSPDNKPSLQIKEENAVFKIPLRPRESLETENVLDDIKSAGSHEPIKIQTRSDHGGCELASVLQLNPCRTGKIKSLQNNQDVSFENIQWSIDPGADLSQYKMDVTVIDTKDGSQSKLGGETVDMDCTLVSETVLLKMKKQEQKGEKSSNEERKMNDSLEDMFDRTTHEEYESCLADSFSQAADEEEELSTATKK-LHTHGDKQDKVKQKAFVEPYFKGDERETSLQNFPHIEVVRKKEERRKLLGHTCKECEIYYADMPAEEREKKLASCSRHRFRYIPPNTPENFWEVGFPSTQTCMERGYIKEDLDPCPRPKRRQPYNAIFSPKGKEQKT--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R983-1", "uniprot_id": "CTIP_DANRE", "id": "F1R983-1", "name": "DNA endonuclease RBBP8", "aln": "MSITPADLSPASSSDHREKLQELLTAVRDLHDTALQELQAKIAKLKKERCLDAQKLSEFHSKNQHLREQQKIQQEKIRQLEDRLRSGPCDRCTVKEKQIKKTNTELEDNNQRNLSVISELEAERKTLTDENRRLSLELERLRRSGSP-QNTSSEAEEGMIPDSPLRPLSLPVASKMKRRK-------EQNHVRYTETPLSLSHPESRQREQSVAFGCNGKGVLVAETCEMDATSVAERDNKRHFR---------IVVPETCRPDVYPEQVDD----------------------------VDDDDLHIPSHTEQNQKPE--------------------------------------------------------------------LRDCTNILIAGQNDDSPLILRCRPLASQDHQSSIDDVLRTPANSSTCVLTKGKRKHSNGAKKDREISDCRLDADETDIKGIIFASTPANGRLQS--------------------KNQETSEIETTQD-------------------SKKKCLDG---------------------------------------------------------------------------------------------HTPRKSLVQNHHAPFPYDQSWSVDPGADLGQYDTES---SPQPEHQARTDLETLDTDCTFVSHSLLLRGQKTTGQ-SQTTGIGQKANDSLADIFDKTGYGEYESCPQDDSIDLKQDSVYEEEREEDDPEEKPEAAVVFRRPADRKPLVSDSDKSSRNKSFACVEVVRKKDERRKLKGHYCKECEVYYADLPEEEREKKLTSCSRHRYRYIPPSTPENFWEVGFPSTQTCVERGYIKEDEQPDVRIRRRRPYLAMFSPKAKSQKKKH", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.*: :. ....*:* ..:::* * ::: ** :* ** *::***:** ****:*.**.:***:**:***: :*.*: ******:* ****:*.*::::*.: *:*: .*:** :*:** *:.:* :**::** :*:: .... * :. .**.:*****: .:*:. .:::::: **.*.: .: : . : : . . : : :***:* : . :.::: . : **.** . *. : :*.:::.. :.: * ::: . . ** : ::.. :. : . . .. *. ::. *: .* .: : . :: :. . * :.:: ::::. ** :. * :*. .* :. : . : .:: : .**:******.**. : ..: ::: . **:* ***:**.::**: :* : .::.. * **** *:**:* : ***** *. : ::. :. . : .:: * * ....::.: :.*. :******:***** ** *****:****:* *******:******:****..****************:******** : * :**:** *:****.*.*:. ", "identical_positions": 212, "similar_positions": 237, "identity": "23.56%" }, { "cls_id": "homologset.agr.RGD:1308873", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "F1M0A0-1", "uniprot_id": "F1M0A0_RAT", "id": "F1M0A0-1", "name": "Anoctamin", "aln": "-----------------------------------------MVHHSG---------------SIQSFKQQK-GMNISKSEITTEASLKP---SRRS----------------------------------------------LPCLAQSYAHSKSLSQSAS------------------------------------------------LFQSTESESQAPT------------------------------SVTFLSADKPEHVTSEESRKDSTLKCSFADLSEFCLALGKDKDYMDESEHANYDRSRLLNDFVTKDKPESKTKLSKNDMNYIASSGLLFKDGKKRIDYILVYRKTNI---------QYDKRNTFEKNLRAEGLMLEKE--PAVANPDIMFIKVHIPWDTLCKYAERLNIRVPFRKKCYYTDQKNKSM-SRVQKYFKRIKKWMSQNPMVLDKSAFPELEESDCYTGPFSRARIHHFIINNKDTFFSNATRSRIVYHMLERTKYENG--ISKVG-----------------------------IRKLINNGSYIAAFPPHEGAYKSSLPIKTHGPQNNRHLLYERWARWGMWYKHQPLDLIRLYFGEKIGLYFAWLGWYTGMLIPAAVVGLCVFFYGLVTMNE--SQVSQEICKAT---EVFMCPLCDKNCSLQRLNDSCIYAKVTYLFDNGGTVFFAIFMAIWATVFLEFWKRRRSILTYTWDLIEWEEEE---------ETLRPQFEAKYYRMEIINPITGKPEPHQPSSDKVTRLLVSVSGIFFMISLVITAVFAVVVYRLVVMEQFASFKWNFIKQHWQFATSGAAVCINFIIIMLLNLAYEKIAYLLTNLEYPRTESEWENSFALKMFLFQFVNLNSSIFYIAFFLGRFVGHPGK---YNKLFERWRLEECHPSGCLIDLCLQMGVIMFLKQIWNNFMELGYPLIQNWWSRHKIKRGIQDAS----IPQWENDWNLQPMNIHGLMDEYLEMVLQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPLPARATDIGIWLGILEGIGILAVITNAFVIAITSDYIPRFVYEYKYGPCANHVKQNENCLKGYVNNSLSFFDLSELGIG--------KSGYCRYRDYRGPPWSSKPYEFTLQYWHILAARLAFIIVFEHLVFGIKSFIAYLIPDIPKGLRERIRREKYLVQEMMYEAELEHLQQQ---------------------------------RRKSGQPIHHEWP-------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2AHL1-1", "uniprot_id": "ANO3_MOUSE", "id": "A2AHL1-1", "name": "Anoctamin-3", "aln": "-----------------------------------------MVHHSG---------------SIQSFKQQK-GMNISKSEITTEASLKP---SRRS----------------------------------------------LPCLAQSYAHSKSLSQSAS------------------------------------------------LFQSTESESQAPT------------------------------SVTFLSADKPEHVTSEESRKDSTLKCSFADLSDFCLALGKDKDYLDESEHANYDRSRLLNDFVTKDKPASKTKLSKNDMSYIASSGLLFKDGKKRIDYILVYRKTNI---------QYDKRNTFEKNLRAEGLMLEKE--PAIANPDIMFIKIHIPWDTLCKYAERLNIRVPFRKKCYYTDQKNKSK-SRVQNYFKRIKKWMSQNPMVLDKSAFPELEESDCYTGPFSRARIHHFIINNKDTFFSNATRSRIVYHMLERTKYENG--ISKVG-----------------------------IRKLITNGSYIAAFPPHEGAYKSSLPIKTHGPQNNRHLLYERWARWGMWYKHQPLDLIRMYFGEKIGLYFAWLGWYTGMLIPAAVVGLCVFFYGLVTMNE--SQVSQEICKAT---EVFMCPLCDKNCSLQRLNDSCIYAKVTYLFDNGGTVFFAIFMAIWATVFLEFWKRRRSILTYTWDLIEWEEEE---------ETLRPQFEAKYYRMEVINPITGKPEPHQPSSDKVTRLLVSVSGIFFMISLVITAVFAVVVYRLVVMEQFASFKWNFVKQHWQFATSGAAVCINFIIIMLLNLAYEKIAYLLTNLEYPRTESEWENSFALKMFLFQFVNLNSSIFYIAFFLGRFVGHPGK---YNKLFERWRLEECHPSGCLIDLCLQMGVIMFLKQIWNNFMELGYPLIQNWWSRHKIKRGIQDAS----IPQWENDWNLQPMNIHGLMDEYLEMVLQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPLPARATDIGIWLGILEGIGILAVITNAFVIAITSDYIPRFVYEYKYGPCANHVKQNENCLKGYVNNSLSFFDLSELGMG--------KSGYCRYRDYRGPPWSSKPYEFTLQYWHILAARLAFIIVFEHLVFGIKSFIAYLIPDIPKGLRERIRREKYLVQEMMYEAELEHLQQQ---------------------------------RRKSGQPIHHEWP-------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BYT9-1", "uniprot_id": "ANO3_HUMAN", "id": "Q9BYT9-1", "name": "Anoctamin-3", "aln": "-----------------------------------------MVHHSG---------------SIQSFKQQK-GMNISKSEITKETSLKP---SRRS----------------------------------------------LPCLAQSYAYSKSLSQSTS------------------------------------------------LFQSTESESQAPT------------------------------SITLISTDKAEQVNTEENKNDSVLRCSFADLSDFCLALGKDKDYTDESEHATYDRSRLINDFVIKDKSEFKTKLSKNDMNYIASSGPLFKDGKKRIDYILVYRKTNI---------QYDKRNTFEKNLRAEGLMLEKE--PAIASPDIMFIKIHIPWDTLCKYAERLNIRMPFRKKCYYTDGRSKSM-GRMQTYFRRIKNWMAQNPMVLDKSAFPDLEESDCYTGPFSRARIHHFIINNKDTFFSNATRSRIVYHMLERTKYENG--ISKVG-----------------------------IRKLINNGSYIAAFPPHEGAYKSSQPIKTHGPQNNRHLLYERWARWGMWYKHQPLDLIRLYFGEKIGLYFAWLGWYTGMLIPAAIVGLCVFFYGLFTMNN--SQVSQEICKAT---EVFMCPLCDKNCSLQRLNDSCIYAKVTYLFDNGGTVFFAIFMAIWATVFLEFWKRRRSILTYTWDLIEWEEEE---------ETLRPQFEAKYYKMEIVNPITGKPEPHQPSSDKVTRLLVSVSGIFFMISLVITAVFGVVVYRLVVMEQFASFKWNFIKQYWQFATSAAAVCINFIIIMLLNLAYEKIAYLLTNLEYPRTESEWENSFALKMFLFQFVNLNSSIFYIAFFLGRFVGHPGK---YNKLFDRWRLEECHPSGCLIDLCLQMGVIMFLKQIWNNFMELGYPLIQNWWSRHKIKRGIHDAS----IPQWENDWNLQPMNLHGLMDEYLEMVLQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPLPARATDIGIWLGILEGIGILAVITNAFVIAITSDYIPRFVYEYKYGPCANHVEPSENCLKGYVNNSLSFFDLSELGMG--------KSGYCRYRDYRGPPWSSKPYEFTLQYWHILAARLAFIIVFEHLVFGIKSFIAYLIPDVPKGLHDRIRREKYLVQEMMYEAELEHLQQQ---------------------------------RRKSGQPVHHEWP-------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TLC9-1", "uniprot_id": "A0AB32TLC9_DANRE", "id": "A0AB32TLC9-1", "name": "Anoctamin", "aln": "--------MSPAFIFCWTPGSLSG---------------IIMVHHSG---------------SIQSFKQQKAGMHTSISEILKEKTLKS---SRRS----------------------------------------------LPCLAQSQTHPENLNHFLS------------------------------------------------VPLSPGPKSYTHS------------------------------SSVSASCTHITPPATDTGQD-----------------VYTEERETGGFEPKTDETLLVQQKPVSRGKLEARTDSVKG-KNLETPSGLMFRDGKKRIDYILVYKKSSP---------QVEKRCTFERNLRAEGLMLEKE--PSLTNSDIMFVKIHAPWDTLCKYAEQMNIRMPFRKKCYFTDWKKKAMGSRFQLRFRQLKSWLPRNPMKLDKEALPDLVETDCYTAPFCRARMHHFTINNRETFFSNSTRSRIVHHVLQRTKYEDG--KSKMAPPLCCLNLLYYYGQHERLLIGQSGSSWEGINRLLGNSTYEAAFPPHEGCYKSRHPIKTHGAQNHRHLLYERWARWGIWYKYQPLDLIRRYFGEKIGLYFAWLGWYTGMLIPAALVGLFVFLYGLFTMDS--SQVSKEICEAN---TTVMCPMCEGNCSSWTLSDSCVYAKVTHLFDNGGTVFFAIFMAIWATVFLEFWKRRRAELTYDWDLIDWEEEECKPCVMVCSEELRPQFEAKYSRKERVNPISGKPEPFQPLTDKLSRLMVSVSGIFFMISLVLTAVFAVVVFRLIAMEKFVSFQWEFVKKNWQFATSGTGVCINFMIIMSLNVVYEKVAYLLTNLEHPRTESEWENSFALKMFLFQFVNLNSSTFYIAFFLGRFAGRPGD---YNKLFNRWRMEECHPSGCLIDLCLQMGVIMVLKQIWNNFMELGYPLLQNWWSRRKMKRAGEQSNSKEELPQWDRDWNLQPMNAHGLVDEYLEMVLQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPMPARATDIGIWHGVLEGIGVVAVITNAFVIAITSDYIPRFVYAIKYGPCVDKGYRHEKCLRGYLNNSLSVFDMGELRNGS------YENQYCRYRDYRAPPWSPEPYEFTLQFWHVLAARLAFIIVFEHLVFGIKTFIAHMIPDMPKDLCDRMRREKYLMQEMVYEAELEHLQKE---------------------------------RKKNGKRYHHEWP-------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9PI24-1", "uniprot_id": "M9PI24_DROME", "id": "M9PI24-1", "name": "Anoctamin", "aln": "MSSQEGRSGERSHIFQIRIDSVEDESTAPITEANSREDLIGSAAQEGDRISEQSVFQFPRFLSVPTLRSPRQSPDPSTTRQVMSSPAKSERMSRRSQTKLRPRRLSQDSGIVAGRLIGYGEGALIDSDLQPRHVESDPIDSVYSCQASHNVPVDSPSKPATPIPPKSKLSASRARAGSAAYTEKWLNSSVMRTSNGNPLFPKSNAIARPLPTHLEADSAEPSPTQAFGPKIVGNNDEDIPGTAMRRSLGLNLSPTLGSADRVNQSYEVMESSHSNVLPDQFGYRQLIPTERKASDTASSVSGSYYGSRKASKSNSLGGESGDERRVSKQDREGLDPESLMFRDGRRKVDMVLAWEEEDLGVMTEAEAKRRDNRRSFMENLIKEGLEVELEDKSQSFNEKTFFLKIHLPWRLETRLAEVMNLKLPVKRFITISVKPSWDEENVVLRNMQYWKDVWQRLTKKIQLDQTLLEGETTFKAATANGNPEEQFIVKDRATAFTSAQRSLMVMQVLIRTPFDESDRSG--------------------------------IRRLMNDGTYLGCFPLHEGRYDRP---HSSGISLDRRVLYQTWAHPSQWYKKQPLCLVRKYFGDKIALYFCWLGFYTEMLVYPAVVGTLCFIYGLATLESEDNTPSKEICNEYGTGNITLCPLCDKACSYQRLSESCLFSRLTYLFDNPSTVFFAIFMSFWATTFLELWKRKQSVLVWEWDLHNVDMDE----------ENRPEFETNATTFR-MNPVTREKEPYMSTWNRSIRFVITGSAVLFMISVVLSAVLGTILYRITLVSVIYGGGGFFVKEHAKLFTSVTAALINLVVIMILTRIYHRMAIKLTNLENPRTHTEYEDSYTFKIFFFEFMNFYSSLIYIAFFKGRFFDYPGDDQARKSEFFRLKNDICDPAGCLSELCIQLAIIMVGKQCWNNFMEYLFPKFWNWWRQRKHKQATKDES--HLHMAWEQDYHMQDPGRLALFDEYLEMILQYGFVTLFVAAFPLAPLFALLNNVAEIRLDAYKMVTQARRPLAERVEDIGAWYGILRIITYTAVVSNAFVIAYTSDFIPRMVYKFVYS--------ETHTLAGYIEHSLSIFNTSDYKEEWGASVSEKDPDTCQYRGYRNGPKDYEPYGLSPHYWHVFAARLAFVVVFEHVVFVITGIMQFIIPDVPSEVKTQMQREQLLAKEAKYQHGIKRAQGDSQDIMSLFRDTSNRASIAGSTVTTRGSWARRFSRLSDGLDAHVEVAARPRRSVESTVWEVSXHEEEAESEAQDQSKR", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :.* *: :::. : . . * :. . . *. **** .* *. . .. .: : : ..* : * . * : . . . . . :. .: . * . ... :*:**::::* :*.:.: . : ::* :* .** *** :* * . . . :*:*:* ** : ** :*:::*.:: : . . . :: *. : . :: . *: :.. .:* :::: * *:.: ** :* ::* ** :::. . *.:*: :.:* ..** *** *. :: * . .*::**: **: . *** *** *:* ***:**.***.***:** **: .*:** *:*** *::. . *:***: :**:*: ** *.:**:::::*:**** .********::***.***:***::: *.: *** : : :* **:**:: . :**:: : **. . :: *:::: *.::****:*::**:..:::*: :. : . *:*: :: ** :.. **:::** *. *.::* ***** ***.:*:*:*:::*:*:*:*:*: ** :***** *** . **. :. * * : : *.*:*** :**:*:.:**. ** ****** :* : *** ::* *:. .: . *:.*:::* . .*.******:**:**.*:**********:*****: ********:*** ***:. *. *** * *:*. * **::****** ***:***:** *. : * **:::***.*: .: . *:**.** * . :** :: ::**::******::****:** *. :: .:***:*. : :::**: * :* *: ::: * : * ..* * * . ", "identical_positions": 329, "similar_positions": 317, "identity": "25.29%" }, { "cls_id": "homologset.agr.RGD:1308874", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q7TP48-1", "uniprot_id": "APMAP_RAT", "id": "Q7TP48-1", "name": "Adipocyte plasma membrane-associated protein", "aln": "----------------------------------------MTFLMLAVSLAIPLLGAMMLLESPIDPQSFSFKEPPFMFGVLQPNTKLRQAERLFENQLNGPESIVNIGDVLFTGTADGRVVKLENGEIETIARFGSGPCKTRDDEPTCGRPLGIRVGPNG-TLFVVDAYKGLFEVNPQKRSVKLLLSSETPIEGKKMS----FVNDLTITRDGRKIYFTDSSSKWQRRDYLLLVMEGTDDGRLLEYDTVTKEVKVLLDQLQFPNGVQLSPEEDFVLVAETAMARIRRVYVSGLMKGGADMFVENMPGFPDNIRPSSSGGYWVAAATIRANPGFSMLDFLSDKPFIKRMIFKLFS---------------------------QETVMKFVPRYSLVLEVSDSGAFRRSLHDPDGQVVTYVSEAHEHDGYLYLGSFRSPFICRLSLQSI------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D7N9-1", "uniprot_id": "APMAP_MOUSE", "id": "Q9D7N9-1", "name": "Adipocyte plasma membrane-associated protein", "aln": "MSEADGLRQRRPLRPQVVT-DDGQVPEVKEGSSFSGRVFRMTFLMLAVSLAIPLLGAMMLLESPIDPQSFSFKEPPFMFGVLHPNTKLRQAERLFENQLSGPESIVNIGDVLFTGTADGRVVKLENGEIETIARFGSGPCKTRDDEPTCGRPLGIRAGPNG-TLFVVDAYKGLFEVNPQKRSVKLLLSSETPIEGKKMS----FVNDLTVTRDGRKIYFTDSSSKWQRRDYLLLVMEATDDGRLLEYDTVTKEVKVLLDQLQFPNGVQLSPEEDFVLVAETTMARIRRVYVSGLMKGGADMFVENMPGFPDNIRPSSSGGYWVAAATIRANPGFSMLDFLSDKPFIKRMIFKMFS---------------------------QETVMKFVPRYSLVLEVSDSGAFRRSLHDPDGQVVTYVSEAHEHDGYLYLGSFRSPFICRLSLQSI------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HDC9-1", "uniprot_id": "APMAP_HUMAN", "id": "Q9HDC9-1", "name": "Adipocyte plasma membrane-associated protein", "aln": "MSEADGLRQRRPLRPQVVTDDDGQAPEAKDGSSFSGRVFRVTFLMLAVSLTVPLLGAMMLLESPIDPQPLSFKEPPLLLGVLHPNTKLRQAERLFENQLVGPESIAHIGDVMFTGTADGRVVKLENGEIETIARFGSGPCKTRDDEPVCGRPLGIRAGPNG-TLFVADAYKGLFEVNPWKREVKLLLSSETPIEGKNMS----FVNDLTVTQDGRKIYFTDSSSKWQRRDYLLLVMEGTDDGRLLEYDTVTREVKVLLDQLRFPNGVQLSPAEDFVLVAETTMARIRRVYVSGLMKGGADLFVENMPGFPDNIRPSSSGGYWVGMSTIRPNPGFSMLDFLSERPWIKRMIFKLFS---------------------------QETVMKFVPRYSLVLELSDSGAFRRSLHDPDGLVATYISEVHEHDGHLYLGSFRSPFLCRLSLQAV------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q803F5-1", "uniprot_id": "APMAP_DANRE", "id": "Q803F5-1", "name": "Adipocyte plasma membrane-associated protein", "aln": "MNEPEGLRFRRLNRPHIIT-DETHEPQYKATSTYSGKVFRVTLLTMVAFLLLPLLVVVFVLESPIQPEVFSLNEPPLMTGCYEPNLKLRQAERLFEERLVGPESLANIGDVFYTGTADGKIVKIEGRNIHVLATIGKPPCGSREHEHTCGRPLGIRVGPNG-TLFVADAYLGLFEVNPVTGEVKSLVSTEKRIAGRRLG----FVNDLDVTQDGKKVYFTDSSSRWQRRDFMHLIMEATADGRVLEYDTETKEVNVMMENLRFPNGIQLFPDEESVLVAETTMARIKRVHVSGLNKGGMDTFIENLPGFPDNIRRSSSGGYWVAMSAVRPNPGFSMLDFLSQRPWLKKLIFKLFS---------------------------QDTLLKFVPRYSLVVELQSDGTCVRSFHDPQGLVSAYSSEAHEYSGHLYLGSFRSPYLCKLDLSKV------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VB46-1", "uniprot_id": "APMAP_DROME", "id": "Q9VB46-1", "name": "Adipocyte plasma membrane-associated protein Hemomucin", "aln": "--------------------------------MGLLYALRVRIMNFMIFFLLIILMPGLPPRTTFPFKDYIVTPPKDLKGALESNFHLEGAERLLEGRVYGPECLIARNNEIYTGIHGGEVIKLTSN-HVTHVTKIGQPCEDIYEESRCGRPLGLAFDTQGNNLIIADAYYGLWQVDLGTNKKTLLVSPAQELAGKSINRPAKIFNGVTVSKEG-DVYWTDSSSDFTIEDLVFASFANPS-GRLFKYNRSKNVSEVLLDELAFANGLALSPNEDFIVVAETGAMRLTKYHLKGAKAGQSEVFVDGLPGLPDNLTPDAEG-IWVPLVQSADSEHPNGFTLFTRFPSVRLFLARMLALFELPFRYLNSVYPNKFSQRFVHFVGHMESITVLAPKRTTVVRVDWNGNIVGSLHG-FDKSAATVSHVLEFQDFLFLGSPTNQYLARVKSPKAKQPTLKVRNVRVEGEGLEASIGVPPSKATPKPKAAPSTTTPKPTTTTTTTTPKPTTKTTTTTTTPKPTTTTTTKKPTTTTTTTTTTPKPTTTKPPTAKPSTTTTTTTTPKPTTTTTPTTPTPEPSKPKVKRTVPEKPAPVEEDIPSDTQPPKKEKLKVINKQGVNVEL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VAQ9-1", "uniprot_id": "Q9VAQ9_DROME", "id": "Q9VAQ9-1", "name": "", "aln": "--------------------------------MGFLAALLKTSLFLVLFLGSLFLLPVLYPSTTFPFEQYFIKPARDLNGTLELNNHLNGARKLWKDQIFGPECLIVLEDKIYTGIHSGEVIRLNNEESVQPITKIGQPCDYIFDDELCGYPVGLALDTQGNNLIVSDAYYGIWQVDLETKKKTVLVPAEQILPGKGANRRAKLFNSLVISRQG-DIFWTDSFS----EDFVFAAFANPS-GRLFRYDRVKKTNEVLLDELSFANGLALSPSEDFIILAETTAMRLRRYYLKGSRAGESEVFVEGLPGCPDNLTADEEG-IWVPLSVASDSQNPNLFAVLAPYPRLRSFLARLVALMRLPLRVLNHIYPNDIAARLFHSFN--DLVIRNAPKRSTVVRVDWNGNIVRSLHG-FDRSASGISHVLEVKGHLYLGSPFNHYVAKVKLP---------------EEGLKSVKGN-------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : :* : :.: : .. . : * . * :*. *.:* : :: ***.: : ::** .*.:::: . ** .: ** *:*: ..:* .*:: *** *:::*: . . . *:.. : *: . :.*.: ::::* .:::*** * .* : : . **::.*: .. :*::::* *.**: * * *: :::*** *: : ::.* * : *::.:** ***: . .* ** . . : .:: * :: :: ::.: : : .*: : *:.:. .* *:*. . : *.. * ...*:*** . ::.::. ", "identical_positions": 72, "similar_positions": 143, "identity": "11.69%" }, { "cls_id": "homologset.agr.RGD:1308875", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5Y5T5-1", "uniprot_id": "ZDHC8_MOUSE", "id": "Q5Y5T5-1", "name": "Palmitoyltransferase ZDHHC8", "aln": "--------------------------------------MPRSPGTRLKPAKYIPVATAAALLVG----------------------SSTLFFVFTCP--WLTRAVSPAIPVYNGILFLFVLANFSMATFMDPGVFPRADEDEDKEDDFRAPLYKN-------VDVRGIQVRMKWCATCHFYRPPRCSHCSVCDNCVEDFDHHCPWVNNCIGRRNYRYFFLFLLSLSAHMVGVVAFGLLYVLNHSEGLGAAHTTITMAVMCVAGLFFIPVIGLTGFHVVLVTRGRTTNEQVTGKFRGGVNPFTRGCYGNVEHVLCSPLAPRYVVEPPRMPLSVSLKPPFLRPELLERAVPLKVKLS---DNGLKA--GRSKSKGSLDQLDEKPLDLGPPLPPKIEAGTFGRDLKTPRP--------------------GSAESALSVQRTSPPTPAMYKFRPAFSTGPKTPFCGPNEQVPGPDS-LTLADDSTHSLDFVSEPSLDLPDHGPGGLRPPYPPSPPLNTTDAFSGALRSLSLKAASRRGGDHMTLQPLRSEGGPPTPHRSLFAPHALPNRNGSLSYDSLLNP-GSPSGHACPTHPSVGIASYHSPYLHP------GPS-DPPRPPP-----------RSFSPVLGPRPREPSPVRYDNLSRTIMASIQERKDREERERLLRSQTDSLFGDSGVYDTPSSYSLQQASVLTEGPRGSVLRYGSRDDLVAGPGFGGARNPALQTSLSSLSSSMSRAPRTSSSSLQADQA---NNNAPGPRPGSGSHRSPARQGLPSPPGTPRSPSYTGSKAVAFIHTDLPDRQPSLAMQR-----DHPQLKTPPSKLNGQSPGMARLG----------PAASPMG-----------------PNASPARHTLVKKVS-----------------------GVGGTTYEISV-----------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LHP6-1", "uniprot_id": "A0ABK0LHP6_RAT", "id": "A0ABK0LHP6-1", "name": "Palmitoyltransferase", "aln": "--------------------------------------MPRSPGTRLKPAKYIPVATAAALLVG----------------------SSTLFFVFTCP--WLTRAVSPAIPVYNGILFLFVLANFSMATFMDPGVFPRADEDEDKEDDFRAPLYKN-------VDVRGIQVRMKWCATCHFYRPPRCSHCSVCDNCVEDFDHHCPWVNNCIGRRNYRYFFLFLLSLSAHMVGVVAFGLLYVLNHSEGLGAAHTTITMAVMCVAGLFFIPVIGLTGFHVVLVTRGRTTNEQVTGKFRGGVNPFTRGCYGNVEHVLCSPLAPRYVVEAPRMPLSVSLKPPFLRPELLERAVPLKVKLS---DNGLKA--GRSKSKGSLDQLDEKPLDLGPPLPPKMEAGTFGRDLKTPRP--------------------GSAESALSVQRTSPPTPAMYKFRPAFSTAPKTPFCGPSEQVPGPDS-LTLADDSTHSLDFVSEPSLDLPDHGPGGLHPTYPPSPPLSATDAFSGALRSLSLKAASRRGGDHMTLQPLRSEGGPPTPHRGLFAPHALPNRNGSLSYDSLLNP-GSPSGHACPTHPSVGMAGYHSPYLHP------GPS-DPPRPPP-----------RSFSPVLGPRPREPSPVRYDNLSRTIMASIQERKDREERERLLRSQTDSLFGDSGVYDTPSSYSLQQASVLTEGPRGSVLRYGSRDDLVAGPGFGGARNPALQTSLSSLSSSMSRAPRTSSSSLQADQA---NNNAPGPRPGSGSHRSPARQGLPSPPGTPRSPSYSGSKAVAFIHTDLPDRQPSLAMQRPGIDTHQGTLKPVAEELVCATVRAQTLVYVCPMMWCCLGSSSQHGASDRKLTGCMLSSDHETPSEPPDSKSSVRAVALAS------------------SLASGGLLFMRPCLKLVLLSKAGKWMKCIPESGACSLSSLSQQESCECMCQPSTHHCCGPSQQSHRLFFHPLSTHFLTSTQSTGPL----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ULC8-1", "uniprot_id": "ZDHC8_HUMAN", "id": "Q9ULC8-1", "name": "Palmitoyltransferase ZDHHC8", "aln": "--------------------------------------MPRSPGTRLKPAKYIPVATAAALLVG----------------------SSTLFFVFTCP--WLTRAVSPAVPVYNGIIFLFVLANFSMATFMDPGVFPRADEDEDKEDDFRAPLYKN-------VDVRGIQVRMKWCATCHFYRPPRCSHCSVCDNCVEDFDHHCPWVNNCIGRRNYRYFFLFLLSLSAHMVGVVAFGLVYVLNHAEGLGAAHTTITMAVMCVAGLFFIPVIGLTGFHVVLVTRGRTTNEQVTGKFRGGVNPFTRGCCGNVEHVLCSPLAPRYVVEPPRLPLAVSLKPPFLRPELLDRAAPLKVKLS---DNGLKAGLGRSKSKGSLDRLDEKPLDLGPPLPPKIEAGTFSSDLQTPRP--------------------GSAESALSVQRTSPPTPAMYKFRPAFPTGPKVPFCGPGEQVPGPDS-LTLGDDSIRSLDFVSEPSLDLPDYGPGGLHAAYPPSPPLSASDAFSGALRSLSLKASSRRGGDHVALQPLRSEGGPPTPHRSIFAPHALPNRNGSLSYDSLLNP-GSPGGHACPAHPAVGVAGYHSPYLHP------GATGDPPRPLP-----------RSFSPVLGPRPREPSPVRYDNLSRTIMASIQERKDREERERLLRSQADSLFGDSGVYDAPSSYSLQQASVLSEGPRGPALRYGSRDDLVAGPGFGGARNPALQTSLSSLSSSVSRAPRTSSSSLQADQA---SSNAPGPRPSSGSHRSPARQGLPSPPGTPHSPSYAGPKAVAFIHTDLPEPPPSLTVQR-----DHPQLKTPPSKLNGQSPGLARLG----------PATGPPG-----------------PSASPTRHTLVKKVS-----------------------GVGGTTYEISV-----------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2CEX1-1", "uniprot_id": "ZDH8B_DANRE", "id": "A2CEX1-1", "name": "Palmitoyltransferase ZDHHC8B", "aln": "--------------------------------------MPNSVGKRFKPTKYIPVSTAATLLVG----------------------STTLFFVFTCP--WLTKAVSPVVPLYNGIVFLFVLANFSMATFMDPGVFPRADEDEDKDDDFRAPLYKN-------VEIKGIQVRMKWCATCHFYRPPRCSHCSVCDNCVEEFDHHCPWVNNCIGRRNYRYFFLFLLSLSVHMVGVFSFGLLFVLHHLETLSALHTTVTLVVMCVTGLFFIPVMGLTGFHMVLVARGRTTNEQVTGKFRGGVNPFTRGCGGNVKHVLCSPLAPRYIAD-PRKKIPVTVTPPFLRPDLSNR--HISVKVS---DNGIHSNILRSKSKTSLNGMDDKSIDAQPPLPPKADR---YNQIKSQLT--------------------SSEESSLSSKPTNPSTPAMFKYRPSFGTMPKVHYHATGEKIVMCENGNPSAVLEERSHDYRSEPNLDLPDYRSAPLHRTYQSSP--FQLDSFSTTSRSFSLKQGVNR-ADCTPLGGTKHETITSTPHRGVFSPGTLSGRNSSLSYDSLLTPSVAPSIGECAAHPGVPSMGFHSPYLPTKMCHVRGPELQRHAGPPSYSPVHIGAMYGRQSPLSRERERDPSPVRYDNLSKTIMASIQERKEFEEREKLMHRHVQGYANDSGVFDT--AYGLPHG--YPDGPRGPASREPTPPVCASRDNLMG--YPPRTPVLRSSASSLVRAPRTSTTSLHTDGG---GMN----RTAELQYRSPVHQSHQSPTSVPRSPSYAHQK-VAFISALERADSPHLGTRE----------DIGQGKVNG-------------------QLKGQYG----------------TPSGTPSRHTSVKKVT-----------------------GVGGTTYEISV-----------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W345-1", "uniprot_id": "ZDHC8_DROME", "id": "Q9W345-1", "name": "Palmitoyltransferase ZDHHC8", "aln": "--------------------------------------MPKCDVK----TRYIPATFAWIVLLL----------------------TTFLFFFYPCQ--FYVKSH-PWVLAYQGVITFFVLANFTLATFMDPGIIPKASPDEDCEEELRAPLYKN-------AEINGITVKMKWCVTCKFYRPPRCSHCSVCNHCIETFDHHCPWVNNCIGRRNYRFFFFFLVSLSIHMLSIFSLCLVYVLKIMPNIKDTAPIVAIILMGLVTILAIPIFGLTGFHMVLVSRGRTTNEQVTGKFKGGYNPFSRGCWHNCCYTQFGPQYPSLLNPKKYASRRSQVQNQAISTICNDRSGQQTGAGSGAGGNGTAAVSGGGGGVGSGGGMRGTAVQYSPRSFYDASREKRGIQVKTYMAEGNGYNQRSGSTTLYSKLSPGRECSDTDLEPPPASQSQDCEPTPPLQRHNSSSFYLPQVSDSGGLN-GSVSTGGGGGGDSPRHMRLYHPRHSPHARPRGLDPQRGYTSDALSPDHPVGYGVGVNGSQQQQQQALAAAAAAAAVAAQNQRSATTTATPTMQQRIKPLGVATP-LVMASPVRRSNPGTPTQPRRPDFIGLNAQAVAQQQQQQQQAAAA-------AAAAYYEYTSGLPPQHPQAPSIQQQQQQLLLQQQRVLMQHQQQQQALQQQQQQQQQAAVHAAHPQHAALAQAAYGGSPQRRFLSEGELVRQGAGGGVAGGELSYARSNNTVDNIRELAGSPQRGVYMWKDTSPGFTNNAGQQQQQQQQAQQVVSSGIGSSAGTLSSSGAAAGVMPHAQYMTAGGGAHPLIMTHSRLQDYTIQQQQQQQQQQAAAAAAASYHRSNPTSPTTMPQVSGAGQSYILRYGGGGAVGAAGSSGSLASVTASNPATGGGGYQPALRGGVAVFPPNPMGNQGGGNLQTQPSPQIKRKQTPTRPMSFVRALEMADSMEMQSLEQQQNGGIPGSGSVGNNQQAGGGGGGHLMQSNASNSGTPDRASIYDMNYEISV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06551-1", "uniprot_id": "ERFB_YEAST", "id": "Q06551-1", "name": "Palmitoyltransferase ERF2", "aln": "MALVSRRSTRSESTSITKEEHTGEGSLTKLFFRWLVTLEGDQDINDGKGYISLPNVSNYIFFLGGRFRTVKGAKPLWLGVLLAIVCPMVLFSIFEAHKLWHTQNGYKVLVIFFYYFWVITLASFIRTATSDPGVLPRNIHLSQLRNNYQIPQEYYNLITLPTHSSISKDITIKYCPSCRIWRPPRSSHCSTCNVCVMVHDHHCIWVNNCIGKRNYRFFLIFLLGAILSSVILLTNCAIHIARESG--GPRDCPVAILLLCYAGLTLWYPAILFTYHIFMAG-----NQQTTREFLKGIGSKKN------------PVFHRVVKEENIYNKGSFLKN--MGHLMLEPRGPSFVSAR-----------------KPHEAGDWRFMDLSPAHSFEKIQKI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :* .:: . ** .: . : .: : : . .:.**.* :: ***::*: .: :: : * . . : :*:* :*:::****.****.*: *: .**** *******:****:*::**:. : :.: :.: . ::: :: . : * :*:.:. *:*.* :* * .. .. * : : : : . :: * . ", "identical_positions": 51, "similar_positions": 84, "identity": "5.01%" }, { "cls_id": "homologset.agr.RGD:1308876", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K2Y3-1", "uniprot_id": "EVA1B_MOUSE", "id": "Q8K2Y3-1", "name": "Protein eva-1 homolog B", "aln": "---------------------------MDAPRRDMELLSN--------SLAAYAHIRANPESFGLYFVLGVCFG--------------------------------------------------------LLLTLCLLVIS--ISCAPRSRPRTPAPRRDPRSSTLEPEDEDDEEDEDTMTRLGPDDTLQGQELSTEPDGPLSVNVFTSAEELERAQRLEERERILREIWRTGQPDLLGSGTLGPG--ATATLGRMHYY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NVM1-1", "uniprot_id": "EVA1B_HUMAN", "id": "Q9NVM1-1", "name": "Protein eva-1 homolog B", "aln": "---------------------------MDAPRRDMELLSN--------SLAAYAHIRANPESFGLYFVLGVCFG--------------------------------------------------------LLLTLCLLVIS--ISWAPRPRPRGPAQRRDPRSSTLEPED-DDEDEEDTVTRLGPDDTLPGPELSAEPDGPLNVNVFTSAEELERAQRLEERERILREIWRTGQPDLLGTGTLGPSPTATGTLGRMHYY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6AD57-1", "uniprot_id": "A0A8I6AD57_RAT", "id": "A0A8I6AD57-1", "name": "", "aln": "AASPAASCRGAGAAPSPLPPGARSSSLLLAPPRPVPPLSSEETFRPLVCRGVRQHRRTNPVRRTGRPGPGICGDREDTSAGARLRDADGVEQLREERAPCALEDLTWVTSQADRRAAPQQHGCPEKGHGATQQQPCSLCAHPSISCAPRSRPRTPAPHRDPRSSTLEPEDEDDED-EDTMTRLGPDDTLQGQELSTEPDGPLSVNVFTSAEELERAQRLEERERILREIWRTGQPDLLGSGTLGPG--ATATLGRMHYY", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ** * : **. . .. * *:** *:* . * * ** ***.*** ** :************ ***: ***:********* * ***:******.************************************:*****. **.********", "identical_positions": 111, "similar_positions": 18, "identity": "42.86%" }, { "cls_id": "homologset.agr.RGD:1308877", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZVK3-1", "uniprot_id": "D3ZVK3_RAT", "id": "D3ZVK3-1", "name": "tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6", "aln": "------------MELSAAEQPSPQPPHLGDHCIHDGDFVVLKREDVF-------------------KAVQVQRRKKVTFEKQWFYLDNAIGHSYGSTFEVSSGGSLQLR-KKLEEPTSETKEAGTDNRNIVDDG-KSQKLTQDDIKALKDKGIKGEEIVQQLIENSTTFRDKTEFAQDKYIKKKKKKYEAIITILKP-STRILSIMYYAREPGKINHMRYDTLAQMLTLGNIRAGNKMIVMETCSGLVLGAMMERMGGFGSIIQLYPGDGPVRAATACFGFPKSFLSGLHEFPLNKVKSLLNGTFSAEMLSSEPKDSTPVKESNGEL-EKEIAEQADKDSIADGPESN--AEQNPVDIVPGDPESKEPKEKGSKRDY-IQEKQRRQEEQRKRHMEAAALLGERNADGLIVASRFHPTPLLLSLLDFVAPSRPFVVYCQYKEPLLECYTKLRERGGVINLRLSETWLRNYQVLPDRSHPKLLMSGGGGYLLSGFTVVSDSHRVDPSLKSCASALDSPKTEEPAAKKQKCMESAS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CE96-1", "uniprot_id": "TRM6_MOUSE", "id": "Q8CE96-1", "name": "tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6", "aln": "------------MEASAAEQPSSPPPPLGDHCIHDGDFVVLKREDVF-------------------KAVQVQRRKKVTFEKQWFYLDNAIGHSYGSAFDVSSGGSLQLR-KKLEEPASETKEAGTDNRNIVDDG-KSQKLTQDDIKALKDKGIKGEEIVQQLIENSTTFRDKTEFAQDKYIKKKKKKYEAIVTILKP-STRILSIMYYAREPGKINHMRYDTLAQMLTLGNIRAGNKMIVMETCSGLVLGAMMERMGGFGSIIQLYPGDGPVRAATACFGFPKSFLSGLYEFPLNKVNSLLNGTFSAEMLSSEPKDSTPVEESNGELEEKEIAEQADEDNIVDAAENNS-GEQRPMEIVPGDPENKEPKEKRSKRDY-IQEKQRRQEEQRKRHLEAAALLGERNADGLIVASRFHPTPLLLSLLDFVAPSRPFVVYCQYKEPLLECYTKLRERGGVINLRLSETWLRNYQVLPDRSHPKLLMSGGGGYLLSGFTVVSDSLRADPSLKSCTGALDPHKAEEPAAKKQKCMESAS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UJA5-1", "uniprot_id": "TRM6_HUMAN", "id": "Q9UJA5-1", "name": "tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6", "aln": "------------MEGSG-EQPGPQPQHPGDHRIRDGDFVVLKREDVF-------------------KAVQVQRRKKVTFEKQWFYLDNVIGHSYGTAFEVTSGGSLQPK-KKREEPTAETKEAGTDNRNIVDDG-KSQKLTQDDIKALKDKGIKGEEIVQQLIENSTTFRDKTEFAQDKYIKKKKKKYEAIITVVKP-STRILSIMYYAREPGKINHMRYDTLAQMLTLGNIRAGNKMIVMETCAGLVLGAMMERMGGFGSIIQLYPGGGPVRAATACFGFPKSFLSGLYEFPLNKVDSLLHGTFSAKMLSSEPKDSALVEESNGTLEEKQASEQENEDSMAEAPESNHPEDQETMETISQDPEHKGPKERGSKKDY-IQEKQRRQEEQRKRHLEAAALLSERNADGLIVASRFHPTPLLLSLLDFVAPSRPFVVYCQYKEPLLECYTKLRERGGVINLRLSETWLRNYQVLPDRSHPKLLMSGGGGYLLSGFTVAMDNLKADTSLKSNASTLESHETEEPAAKKRKCPESDS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N890-1", "uniprot_id": "A0A8M1N890_DANRE", "id": "A0A8M1N890-1", "name": "tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6", "aln": "------------MAECVNDSDE-------DSRIAYGDYVVLKRGEVF-------------------KSVQVENKKKVIFEKQWFFMDNAVGQLYGTMFEIVAGGSLKHKPVKRAGDSLDSKEAGQDNRHIVDDG-RSQKLTRDDIETLKEQGLKGQEIVQQLIDNSTTFKDKTEFAQEKYIKKKKKKYESDITVLKP-STRLLAMMYHGREPGKICHLRYDTLAQMLTLGNIHAGSKIIVFETCAGLVLGSVMERMGGFGSVIQMFPGGGPTRAGMESFGFPSHFHQTLHEFPLCKVNAVLAGKL--------------------DLSEKDTENSRSEE---TAAEKNS--EAQSMEISLDPQEQMRIAERDRLRELRAQEKKVKMEEKRKKLASAAALLQDRNADGLVIASRFHPCPVLMGLLKFVAPSRPFVVYCQYREPLIECYNKLREQGGVINLRLTDSWLRHYQVLPNRTHPVLLMSGGGGYLLSGTTVDAGTAKTKNPHKSEEPDAKRLKLEEKASS---CDSSV-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P41814-1", "uniprot_id": "TRM6_YEAST", "id": "P41814-1", "name": "tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6", "aln": "MNALTTIDFNQHVIVRLPSKNYKIVELKPNTSVSLGKFGAFEVNDIIGYPFGLTFEIYYDGEEVSSDENRDSKPKNKIPIGKVRLLSQEIKDVNNDKDDGQSEPPLSIK-EKSVSLELSSIDSSATNQNLVNMGSKAQELTVEEIEKMKQESLSSKEIIDKIIKSHKSFHNKTVYSQEKYVNRKKQKFAKYFTVEYLSSSNLLQFLIDKGDIQRVLDMSQESMGMLLNLANIQSEGNYLCMDETGGLLVYFLLERM---------FGGDNESKSKGKVIVIHENEHANLDLLKFANYS------------------------------EKFIKEHVHTISLLDFFEPPT-LQEIQSRFTPLPKEEARALKGGKKNSY------YRKLRWYNTQWQILELTGEFLYDGLVMATTLHLPTLVPKLAEKIHGSRPIVCYGQFKETLLELAHTLYSDLRFLAPSILETRCRPYQSIRGKLHPLMTMKGGGGYLMWCHRVIPAPEPVSENATAADS---SEKLAEHGAKKQKI-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .. : : *.: .:: ::: . : .. *: : :.: : . . : : .*. : * .: ::. *:::*: * ::*:** ::*: :*::.:..:**::::*.. .:*::** ::*:**:::**:*: .*: *:.:* :: : :: .: :::. :*.*.**:: .: : :: .**:: ::*** : *.. :: : : . * : : : . ** : * : * : .. : . : . * : ***::*: :* .:: * . : ***:* * *::*.*:* .* . .: : :: * ** : .: ** : *.******: * .. .: : * .:. ", "identical_positions": 73, "similar_positions": 159, "identity": "13.7%" }, { "cls_id": "homologset.agr.RGD:1308878", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZBA8-1", "uniprot_id": "D3ZBA8_RAT", "id": "D3ZBA8-1", "name": "", "aln": "MNMNSMLYLVGFLLATMCLLVLGVNVWVLIDDLRTIDVPPSVLHPVKLRILHYGFHLTTTWGNIFEKMKICSMSQFVCFVQDSLAPKEN---LGMFVKDLHFGTIPVRIFHPKAASSKPRRGIIFCHGGGALIGSLDSYHNLCAFLARETDSVLMSVGYRKLPYYHHPSLYYDCLNASIHFLNSLKV-YGVDPSRVVICGDSIGGAVAAIVTQTLSSRTD--IPKIRAQVLIYPVLQAFYFQSPSHLTNINIPFLTQEFFITCVCKYLAIDLSWKDTMLTGASISPSAWKKYEKWLSPENIPKRFKTEYRPPESPTPFNDAAYLETKHAMNVDISPLLADDKIITQLPEAFIVSLHWDIVRDDVLLYKKRLEDHGVPVTWHHVVDGFHGCMLLFDKKFFSFPCSVNIMHAVVSYIKGL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BM81-1", "uniprot_id": "AD4F1_MOUSE", "id": "Q8BM81-1", "name": "Arylacetamide deacetylase-like 4 family member 1", "aln": "-----MLYLVGFLLATVCLLVLGVNVWVLIDHFLTIDVPPSIPHPVKFRILHFCFHLTTTWGHILEKMNICSMPQFFCFLQDSLSSKEN---HGVFVKDLRFGTIPVRLFRPKAASSKPRRGILFFHGGGAMIGSLDSHHNLCTFLARETDSVLVSVGYRKLPYYHHPSLYHDCINASIHFLKSLKA-YGIDPSRVVICGESIGGAAAVVVTQTLLSRTD--IPKIRAQVLIYPILQAFYFQSPSHLMHKNIPFLTKDFMITCICKYLAIDFSWKDAMLTGACISPSAWKKYEKWLSPDNIPKRFRTTYQPPESPAPFNEAAYLETKHAMNIDISPLVADDKIIAQLPEAFLVSLHWDIIRDDVLLYKKRLEDQGVPVTWHHVEDGFHGCILLFDKKLFSFPCSLNIVNAVVSYIKDL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5VUY2-1", "uniprot_id": "ADCL4_HUMAN", "id": "Q5VUY2-1", "name": "Arylacetamide deacetylase-like 4", "aln": "-----MAVPWLVLLLALPIFFLGVFVWAVFEHFLTTDIPATLQHPAKLRFLHCIFLYLVTLGNIFEKLGICSMPKFIRFLHDSVRIKKD---PELVVTDLRFGTIPVRLFQPKAASSRPRRGIIFYHGGATVFGSLDCYHGLCNYLARETESVLLMIGYRKLPDHHSPALFQDCMNASIHFLKALET-YGVDPSRVVVCGESVGGAAVAAITQALVGRSD--LPRIRAQVLIYPVVQAFCLQLPSFQQNQNVPLLSRKFMVTSLCNYLAIDLSWRDAILNGTCVPPDVWRKYEKWLSPDNIPKKFKNRGYQPWSPGPFNEAAYLEAKHMLDVENSPLIADDEVIAQLPEAFLVSCENDILRDDSLLYKKRLEDQGVRVTWYHLYDGFHGSIIFFDKKALSFPCSLKIVNAVVSYIKGI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NVX1-1", "uniprot_id": "A0A8M1NVX1_DANRE", "id": "A0A8M1NVX1-1", "name": "", "aln": "------MNTATAILISAFAALFAAFCLLVYFELRNVNIPPGVDSPAKLRVIHCTYMGITCLGYILERLGLCHQYNFVGWCRCHIMTCKRSVPHGLRIKDLTFSTVPVRVYEPTAASGEKKRGLVYFHGGGWMFGCIDDYDEVCQHISLKSNTTVVSVGYRLAPEHRYPAHLDDCEVATRHFLSIAATDFGVDPCRVAVGGDSAGANLAAALCQRLSKTQDGHLPSPCAQVLIYPALQMADFHLPSYQQNHSVPILFRGRTVFYFLQYLNGNTSVSQQILEGRHVPAELKLRYKKWLDPNSLPPQFIKQARCQQDLSSHDADVYHIVKQGLDPEISPLLAEDDVLRLVPPAFVLTCEFDVLRDDGFLYQKRLRDLGVDVTWEHLPEGFHGVISFFNQGWLTFQSSQRGLDSIVRYVKSL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* : .:.. : .: . ::*. : *.*:*.:* : . * *:*:: :* :*. : : : : : :.** *.*:***::.*.***.. :**::: ***. ::*.:* :. :* .:: ::::.:: :*** * :: *: ** *: ***. . :*:**.**.: *:* *. .. : * * * :* ******* :* :: **. : .:*:* : : . :** : * : :* * :... :*:***.*:.:* :* . . ..: .* .*: :: : ***:*:*.:: :* **::: . *::*** :**:***.* ** *** *: :**** : :*:: ::* .* . :.::* *:*.:", "identical_positions": 113, "similar_positions": 150, "identity": "27.03%" }, { "cls_id": "homologset.agr.RGD:1308879", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L4K3-1", "uniprot_id": "A0ABK0L4K3_RAT", "id": "A0ABK0L4K3-1", "name": "Probable imidazolonepropionase", "aln": "MPFCLLVLSKEKETHVSKSCSHKSWSQDAGEPPPRPALPRPAPPRPALPRPAPPCPAPPRPAPPLRGATARRLYCPCNPPEARTTKMNGHRLLLENAQQVVLVCARGELYLTGSELRSLAVLEGASLVVGTDGLIKAVGPADIIRRQFSGETFEERIDCSGKCILPGLVDAHTHPVWAGERVHEFAMKLAGATYMDIHQAGGGINFTVEHTRQASEEELFRSFQQRLQCMMRAGTTLVECKSGYGLNLETELKMLRVIERARRELHLSLSATYCGAHSVPKGKTAVEAADDIISHHLPRLKELSEKGELHVDNIDVFCEKGVFDLDTTRRILEGGKKVGLQINFHGDELHPMKAAELGAELGARAISHLEEVSDEGIAAMAAAQCSAVLLPTTAYMLRLKQPRARKMLDEGVIVALGSDFNPNAYCFSMPMVMHLACVNMRMSMPEALAAATINAAYALGKSHTHGSLEVGKQGDAIIINASRWEHLIYQFGGHQELIDYVITKGKVIYKK------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DBA8-1", "uniprot_id": "HUTI_MOUSE", "id": "Q9DBA8-1", "name": "Probable imidazolonepropionase", "aln": "-------------------------------------------------------------------------------------MTSSHRLLLENAQQVVLVCARGERFLTGSALRSLAVLEGASVVVGTDGLIKAVGPAAVIQKQFSGETFEERIDCSGKCVLPGLVDAHTHPVWAGERVHEFAMKLAGATYMDIHQAGGGINFTVEHTRQASEEELFCSFQQRLQCMMRAGTTLVECKSGYGLNLETELKMLRVIERARRELHLSLSATYCGAHSVPKGKTAVEAADDIISHHLPRLKELSRNGDLHVDNIDVFCEKGVFDLDTTRRILEGGKKMGLQINFHGDELHPMKAAELGAELGAQAISHLEEVSDEGIAAMAAARCSAVLLPTTAYMLRLKQPRARKMLDEGVIVALGSDFNPNAYCFSMPMVMHLACVNMRMSMPEALAAATINAAYALGKSHTHGSLEVGKQGDAIIINASRWEHLIYQFGGHHELIDYVITKGKVIYKK------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96NU7-1", "uniprot_id": "HUTI_HUMAN", "id": "Q96NU7-1", "name": "Probable imidazolonepropionase", "aln": "-------------------------------------------------------------------------------------MASGHSLLLENAQQVVLVCARGERFLARDALRSLAVLEGASLVVGKDGFIKAIGPADVIQRQFSGETFEEIIDCSGKCILPGLVDAHTHPVWAGERVHEFAMKLAGATYMEIHQAGGGIHFTVERTRQATEEELFRSLQQRLQCMMRAGTTLVECKSGYGLDLETELKMLRVIERARRELDIGISATYCGAHSVPKGKTATEAADDIINNHLPKLKELGRNGEIHVDNIDVFCEKGVFDLDSTRRILQRGKDIGLQINFHGDELHPMKAAELGAELGAQAISHLEEVSDEGIVAMATARCSAILLPTTAYMLRLKQPRARKMLDEGVIVALGSDFNPNAYCFSMPMVMHLACVNMRMSMPEALAAATINAAYALGKSHTHGSLEVGKQGDLIIINSSRWEHLIYQFGGHHELIEYVIAKGKLIYKT------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7SXK5-1", "uniprot_id": "HUTI_DANRE", "id": "Q7SXK5-1", "name": "Probable imidazolonepropionase", "aln": "------------------------------------------------------------------------------------MSANSFKLLVKNATQLVLVCRNGEKYLTRDEMQALAVLENASVLIGHDGLIKAVGPADVIETQFEGAKFDNVLDASGMCVLPGLVDAHTHPVWAGDRVHEFAMKLAGATYMEVHEAGGGIHFTVAHTRSASEQHLLAALKSRLERMMRAGTTLVECKSGYGLELDIEVKMLRVINSARKSLPIGISATYCGAHAVPKGKTMEEATKDIVAVQLPKIKHLSASGDLQVDNIDVFCEKGVFDLTSTRCILQAGKDMGLNINFHGDELHPMNSAHLGAELGALAISHLEEVTDDGIVAMAKSKTSAVLLPTTAYILRLTPPRARDMLDAGVIVALGSDFNPNAYCFSMPMVMHLACVMMKMSMPEALAASTINAAYALNRSQTHGSLEVGKQGDLVIINAPRWEHLVYQFGGHQELIRYVIIKGDFVYENDKVLNL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ... **::** *:**** .** :*: . :::*****.**:::* **:***:*** :*. **.* .*:: :*.** *:***************:***************::*:*****:*** :**.*:*:.*: :::.**: *****************:*: *:******: **:.* :.:********:****** **:.**: :**::*.*. .*:::*************** :** **: **.:**:***********::*.******* ********:*:**.*** :: **:*******:***. ****.*** **************************** *:*********:********.:*:************ :***:.*****:******:*** *** **..:*:. ", "identical_positions": 291, "similar_positions": 98, "identity": "56.29%" }, { "cls_id": "homologset.agr.RGD:1308880", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5PQJ7-1", "uniprot_id": "TBCEL_RAT", "id": "Q5PQJ7-1", "name": "Tubulin-specific chaperone cofactor E-like protein", "aln": "----------------------------------------------------------------------MDQP--SGRSFMQVLCEKYSPEN-------FPYRRGPGMG-VHVPATPQGSPMKDRLNLPSVLVLNSCGITCAGDEREIAAFCAHVSELDLSDNKLQDWHEVSKIVSNVPQLEFLNLSSNPLSLSVLERTCAGSFSGVRKLVLNNSKASWETVHTILQELPDLEELFLCLNDYETVSCPSVCCHS---LKLLHITDNNLQEWTEIRKLGVMFPSLDTLVLANNHVNAIEEPADSLARLFPNLRSISLHKSGLQSWEDIDKLN-SFPKLEEVRLLG--IPLLQPYTTEERRK---LVVARLPSVSKLNGSVVTDGEREDSERFFIRYYVD--VPQEEVPFRYHELITKYG----KLEPLAEVDLRPQSSAKVEVHFNDQVEE---VSIRLDQTVAELKRQLKTLVQLPTSSMLLYYFDHEAPFG--PEEMKYSSRALHSFGIRDGDKIFVESKTK-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C5W3-1", "uniprot_id": "TBCEL_MOUSE", "id": "Q8C5W3-1", "name": "Tubulin-specific chaperone cofactor E-like protein", "aln": "----------------------------------------------------------------------MDQP--SGRSFMQVLCEKYSPEN-------FPYRRGPGVG-VHVPATPQGSPMKDRLNLPSVLVLNSCGITCAGDEREIAAFCAHVSELDLSDNKLQDWHEVSKIVSNVPQLEFLNLSSNPLSLSVLERTCAGSFSGVRKLVLNNSKASWETVHTILQELPELEELFLCLNDYETVSCPSVCCHS---LKLLHITDNNLQDWTEIRKLGVMFPSLDTLVLANNHLNAIEEPADSLARLFPNLRSISLHKSGLQSWEDIDKLN-SFPKLEEVRLLG--IPLLQPYTTEERRK---LVVARLPSVSKLNGSVVTDGEREDSERFFIRYYVD--VPQEEVPFRYHELITKYG----KLEPLAEVDLRPQSSAKVEVHFNDQVEE---MSIRLDQTVAELKKQLKTLVQLPTSSMLLYYFDHEAPFG--PEEMKYSSRALHSFGIRDGDKIFVESKTK-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5QJ74-1", "uniprot_id": "TBCEL_HUMAN", "id": "Q5QJ74-1", "name": "Tubulin-specific chaperone cofactor E-like protein", "aln": "----------------------------------------------------------------------MDQP--SGRSFMQVLCEKYSPEN-------FPYRRGPGMG-VHVPATPQGSPMKDRLNLPSVLVLNSCGITCAGDEKEIAAFCAHVSELDLSDNKLEDWHEVSKIVSNVPQLEFLNLSSNPLNLSVLERTCAGSFSGVRKLVLNNSKASWETVHMILQELPDLEELFLCLNDYETVSCPSICCHS---LKLLHITDNNLQDWTEIRKLGVMFPSLDTLVLANNHLNAIEEPDDSLARLFPNLRSISLHKSGLQSWEDIDKLN-SFPKLEEVRLLG--IPLLQPYTTEERRK---LVIARLPSVSKLNGSVVTDGEREDSERFFIRYYVD--VPQEEVPFRYHELITKYG----KLEPLAEVDLRPQSSAKVEVHFNDQVEE---MSIRLDQTVAELKKQLKTLVQLPTSNMLLYYFDHEAPFG--PEEMKYSSRALHSFGIRDGDKIYVESKTK-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13AC38-1", "uniprot_id": "A0AB13AC38_DANRE", "id": "A0AB13AC38-1", "name": "", "aln": "----------------------------------------------------------------------MDSSEIEGRTFMQAISEKYSPEN-------FPCRRGPGMGVVVVPSGPQGSPMKDRLNLPSVLVLNGCGISHAGDQGEIAAFCAHVVELDLSHNKLQDWHEISKIVSNVPNLEFLNLSSNQLSDAVLDPDCAKAFSSIRRFVLNNTQVSWDTVHTFTQEMPELEELFLCLNEYTTVTLAAMPCPT---LRLLHITDNNLHEWNEVRKIGSMFPALDTLVMANNNLNSIQESGEILHRLFPNLRSINLHNSGLNRWEDIEKLT-FLPKLEEVRLQG--IPLLQTYTSTERRS---LMIAQLPSVTSLNGSVVTDGEREDAERFFIRYHLD--HSEEELPHRYHCLVTKYG----KLAPLAEIDLRPRFHAKVEVRFEDKVEQ---VSIRLDQTVAELKKQLKTVVQLPTNNMRLYYIDKGTAYG--PDELKYSARALHSYSIQDGDEILVVPKAK-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E9QCV6-1", "uniprot_id": "E9QCV6_DANRE", "id": "E9QCV6-1", "name": "", "aln": "----------------------------------------------------------------------MESEETEGRTLVQVISEKYSPDN-------FPYCRGPGVG-VVIRSSPQGSPVKDRLNLPSILVLDGCGITEAGDEEEVATFCAHVVELDLSHNQLKDWGEISKILSNIPNLDFLNLSMNPLHGSSLEPCLAEAFSGLRRLVLNNTHVTWDMVHTLTREIPDLEELFLCLNEYESVNASSMPCPS---LRLLHITDNQLQDWVEVRKLGLMYPGLVSLILSNNSLSSIHEPEDSLHRLFPNLRSINLHNSGLSRWEDVEKLN-FFPKLQEVRVMG--IPLLQPYTDQERRC---LMVAQLPHVTVLNGSVVTDGEREDAERFFIRYHLD--CPEDELPQRYHTLVARYG----RLAPLAEVDLRPLSHVQVQVRFGDQAKS---LELRLDQTVADLKKQLKTVVQLPPNKIRVYYIDRQLGYALEPQEMKYGARALHSYSIRDGDEIMVVPKTQ-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P39937-1", "uniprot_id": "PAC2_YEAST", "id": "P39937-1", "name": "Protein PAC2", "aln": "MTYEIGDRLKIGGYFCTIKFIGVIKPWPSVKAYGVEWDDHSRGKHSGTIDDIHYFDVQIPNSGSFLKESKIKSPGVRRITFYEALSEKYGGSSNNINDLSIGNKRVEGLGFDELNARNKNYKKLRKIALRDSDVA--ILFQNQDELNRVIQNCVNVKDLDLSLNLFTNINSLCEFIEPLKNLESLNISQNKLLSG-WDNLKEYDLSHIKTLRLSSCGLSYKHIGKLLKSFRTLKMLDLSYNNLTSAGIQNFENEIPCTLEELNISGNNLISFPLFPKN----LTLKGLNVSNNQISRAP------SIAIYSVESLDITDNKFKERSLIDDLNKTFPSLKNIHLSGNEFNYNGNYINVEEQATFYEVLARFDRVMVLNGSICDVKTRREAEMFFVSKVMNNELSYDTNLPRWSSLIKSYEIDMSKLSFNNERETRQSLVLKIKIRAGKKPSSDLDYWVLPSFTVRYVKSVICRKLNFDILNVKLFHENSEGMIN----EIKYNFRPISDFNVVNGDIIHVSSPVNNKSIQKVNSPS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.. :: :.:.***. .. : * *:* : : :. :: * . * : .: .: *.:* :**** * : : .:.:::. : :*: **:* * * . : :* :: : *.. ::. : : :.: *: * *. *: :. . *. *:*:.*:* .: . * * * ::** :. : .:.*:.: .. :. . ::.*. :*.*::::: * : * *.: ::*:: * ****: *.::* **: :: . : *: *: * :* * : * ::::: .: .. : . ** :* : ::: .: ::: : *:**. *.: .:.: :** * * . .: ", "identical_positions": 71, "similar_positions": 153, "identity": "13.27%" }, { "cls_id": "homologset.agr.RGD:1308881", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZX06-1", "uniprot_id": "D3ZX06_RAT", "id": "D3ZX06-1", "name": "", "aln": "MPVLWLLFLLP-LLPLLAMLCQQRSPGARPCWLISLQHRVACVVLSWAAAWQRRKLEQSTLNVSQSQQQALMGCLKEAQGSCCLPRENTDMTTFRN-LPLTKTSHTQQKESEEKLLPPTLPQYHGDASLQATLLGLMTLNKAYPEVLAPGSTACVTPTSPWPYSVPWLGHALGRVSPIGAKDARTLLLEALISPGLRVLEARTAVELLDVFVGLEADGEELAEVIASGSLG-KLPRRAAELQEALEQGPRGLALRLWPKLQVVVTLDAGGQAEAVAALRVLWCQGLAFFSPAYAASGGVMALNLWPEQPQGSYLLSPGVPFIELLPIKEGTQEEAASTLLLTDVRREEKYELVLTDSTSLTRCRLGDVVQVIGTYNQCPVVRFTCRLGQTLSVRGEVTDENVFSVALAQAVGQWPGAKLLDHVCVESHILDSYEGSAPHYEVFVELRGLRNLSEENRDKLDHCLQEASPRYKSLRFWGSVGPAKVHLVRPGSFRVLREALAACPSSSC--PEMPRVLRLRHLAQLLQKRVIP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99J23-1", "uniprot_id": "GHDC_MOUSE", "id": "Q99J23-1", "name": "GH3 domain-containing protein", "aln": "MLLLWLLLLLLLLVPLLAILWQQRSRGARPCWLISLQHRVAWGMLGWAAAWQQWRLDRSTLNVGQSQQQALMWCLKKAQGSCCLPREDTDMRTFRNHLPLTQTSHTQEQESEETLPSPASPQYHGDASLQATLLGLITLNKAYPEALAPGSTACVTPTSPWPCSVPWLGHALGRVSPDGAKDPRTLLLEALISPGLRVLEARTAVELLDVFVGLEADGEELAEAIAAGILGTLLPKRAAELKEALEQGPRGLARRLWPKLQVVVTLDSGGQAEAVAALRVLWCQGLAFFSPAYAASGGVVALNLWPERPQGSYLLPPGVPFIELLPIKEGTQEEAASTLLLTDAQREKEYELVLTNHTSLTRCRLGDVVQVVGTYNQCPVVRFTCRLGQTLNVRGEVTDETVFSVALAQAVGQWPGAKLLDHVCVESRVLDSCEGSAPHYEVFVELRGLRNLSEENRDKLDNCLQEASAQYKSLRFRGSVGPAKVHLVRPGSFRVLREALAAFSSSSCRPPEMPRVIRLRHLAQLLQKRVIS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N2G8-1", "uniprot_id": "GHDC_HUMAN", "id": "Q8N2G8-1", "name": "GH3 domain-containing protein", "aln": "-MLLWPLLLLLLLLPTLALLRQQRSQDARLSWLAGLQHRVAWGALVWAATWQRRRLEQSTLHVHQSQQQALRWCLQGAQRPHCSLRRSTDISTFRNHLPLTKASQTQQEDSGEQPLPPTSNQDLGEASLQATLLGLAALNKAYPEVLAQGRTARVTLTSPWPRPLPWPGNTLGQVGTPGTKDPRALLLDALRSPGLRALEAGTAVELLDVFLGLETDGEELAGAIAAGNPGAPLRERAAELREALEQGPRGLALRLWPKLQVVVTLDAGGQAEAVAALGALWCQGLAFFSPAYAASGGVLGLNLQPEQPHGLYLLPPGAPFIELLPVKEGTQEEAASTLLLAEAQQGKEYELVLTDRASLTRCRLGDVVRVVGAYNQCPVVRFICRLDQTLSVRGEDIGEDLFSEALGRAVGQWAGAKLLDHGCVESSILDSSAGSAPHYEVFVALRGLRNLSEENRDKLDHCLQEASPRYKSLRFWGSVGPARVHLVGQGAFRALRAALAACPSSPFP-PAMPRVLRHRHLAQCLQERVVS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :** *:** *:* **:* **** .** .** .****** * ***:**: :*::***:* ******* **: ** . * *..**: **** ****::*:**:::* * .*: * *:********** :*******.** * ** ** ***** .:** *::**:*.. *:**.*:***:** *****.*** *********:***:****** .**:* * * .*****:*********** *************:********** .*******************:.*** **:*:* ***.**.*******:**************::.:: ::******: :***********:*:*:********* ***.***.**** .* :** **.:*****.******* **** :*** ********** ****************:******.:****** ******:**** *:**.** **** .**. * ****:* ***** **:**:.", "identical_positions": 368, "similar_positions": 88, "identity": "69.17%" }, { "cls_id": "homologset.agr.RGD:1308882", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q29YR5-1", "uniprot_id": "ST2B1_RAT", "id": "Q29YR5-1", "name": "Sulfotransferase 2B1", "aln": "-------MDG---PQPPALWGSLENRVSELSQKLQGEYFRYKGIPFPVGMYTPESLSLAENTSNVRDDDIFIVTYPKSGTNWMIEIICLILKDGDPSWIRSEPIWQRAPWCETTISAFSLPER--------PSPRLMCSHLPIELFTKAAFSSKAKVIYLGRNPRDVVVSLYYYSKIAVQLKDPGTPEQFLQNFLKGEVQFGSWFDHIKGWIRMRGRENFLFITYEELQQDLRGSVQLICEFLGRPLGEEALSSVVAHSAFAAMKANNMSNYTLLPASLLDHR-----QGAFLRKGISGDWKNHFTVAQSETFDQVYREQMHGLPSFPWDRS-AEDGSPDGETEPSP-----------------------------------------------------------SPSPGLASDDPNPGSSQ-------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35400-1", "uniprot_id": "ST2B1_MOUSE", "id": "O35400-1", "name": "Sulfotransferase 2B1", "aln": "-------MDG---PQPRALWSSSEKNVSEMSWNFGGEYFRYKGIPFPVGMYSPESLSLAENTSNVRDDDIFIVTYPKSGTNWMIEIVCLILKDGDPSWIRSEPIWQRAPWCETIISAFNVLDR--------PSPRIMSSHLPIELFTKAFFSSKAKVIYVGRNPRDVVVSLYYYSKIAGQLKDPGTPDQFLQNFLKGEVQFGSWFDHIKGWIRMQNQENFLFITYEELQQDLRGSVQRICEFLGRPLGEEALSSVVAHSAFAAMKANTMSNYSLLPASLLDHR-----QGEFLRKGISGDWKNHFTVAQSEAFDSVYREQMHGVQRFPWDTS-EEDSSPDGQPDPEP-----------------------------------------------------------SPSP--ASDDPNPGSSQ-------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00204-1", "uniprot_id": "ST2B1_HUMAN", "id": "O00204-1", "name": "Sulfotransferase 2B1", "aln": "-------MDGPAEPQIPGLWDTYEDDISEISQKLPGEYFRYKGVPFPVGLYSLESISLAENTQDVRDDDIFIITYPKSGTTWMIEIICLILKEGDPSWIRSVPIWERAPWCETIVGAFSLPDQ--------YSPRLMSSHLPIQIFTKAFFSSKAKVIYMGRNPRDVVVSLYHYSKIAGQLKDPGTPDQFLRDFLKGEVQFGSWFDHIKGWLRMKGKDNFLFITYEELQQDLQGSVERICGFLGRPLGKEALGSVVAHSTFSAMKANTMSNYTLLPPSLLDHR-----RGAFLRKGVCGDWKNHFTVAQSEAFDRAYRKQMRGMPTFPWDEDPEEDGSPDPEPSPEPEPKP-------------------------------------SLEPNTSLEREPRPNSSPSPSPGQASETPHPRPS--------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W1L8-1", "uniprot_id": "Q9W1L8_DROME", "id": "Q9W1L8-1", "name": "", "aln": "MPQSSFFAKSVPFEQIDKLAISGGYSSIFASSKPSVPVVGNWEQRFCRLADTFQPVLDRVYDFEVRDDDVWIVTLPKCGTTWMQELAWLVINECDFETAKSVDLTHRSPFLEFNGVVPNVPHDTIAAANALPSPRLIKSHLPAWMLPRQIWSKRPKIIYVYRNPKDAAIS--YFHHWRGMVGYQGTKSDFMHSFIDGYVNFTPCWPHILDFWQLRHEPNIFFTSYERMKGQLGQVISEVAQFLERSVSQEQMQQMQRHLSFESMRDNPACNHVKEFESMKAAAGREVEEFRFVRRGVVGSHKDELTADIIREFDLWSDSNLRDFKLNMDDFANYSKFAST------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A0B4KF40-1", "uniprot_id": "A0A0B4KF40_DROME", "id": "A0A0B4KF40-1", "name": "", "aln": "---------------MNRVQVTP-------RSYPTNLIDKDWGNRKLFYTKDSENFLRLVHDMKLRDDDVWIVTLPKCGTTWMQELLWLLLNNCDFEGALAKDQELRTPFLEFGYSVFHDPNRSFGPIEDLKSPRLIKSHLSLALLPSKLWEGKNKVIYVSRNPLDSYVSR-YYHGVSFGFNYGKSLHQYFDEVLASDDFPTEFIEHAHEFYQLRNEPWVFYTSFEMMKKDLRGVINDVSRFLNKPINDQQMEKLLKHLSFAEMKKNPTTNHLWELAQVQHEN-AGKEMHPFVRRGDVNGYKDELKPEQIEKANVRIQEVLAKNGVTLDELLLLKDQDWPCSGLCTQHSQTNSEAITLRNGPKAHQHQCSSACTRWLCVRVKVVKAESRGRTGPILMLMQGSRDAEMPTPPPQREAKNGKQATFIAGREVFTVLWERRISQDVNRGSCTMFAPHSLPVTSRLLLLVVTLLFCPVQAHLSKRSYSDQSVHGYMTERTCWWNEVCKEEFQSLFRCKCPQFSYCRSPGRYYNAYCSMTDTGYIWTQPNWDWGA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : . .:****::*:* **.**.** *: *:::: * . : *:*: * . . ***:: ***. ::. :. : *:**: *** * :* :: . : ::: ..: . * : ::: . .:: ::* :: :* :. :. ** :.:..: : .: * :* *: * *: .: *:*:* .. *:.:. . : . : : .. ", "identical_positions": 46, "similar_positions": 91, "identity": "8.36%" }, { "cls_id": "homologset.agr.RGD:1308885", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "F1LMK2-1", "uniprot_id": "F1LMK2_RAT", "id": "F1LMK2-1", "name": "E3 ubiquitin-protein ligase TRIM41", "aln": "MAAVAMTPNPVQTLQEEAVCAICLDYFTDPVSIGCGHNFCRVCVTQLWGGEDEEDRDELDREEEEE-VGEEEEVEAVGAGGGWDTPMRDEDYEGDMEEEAEEEEEGVFWSSGIGGSNWDNMDYVWEEEEEEEE--LDYYLGDVE--DLRVEDEDEEEEVLEEDEEEELDPITQLPPPPAPRRCFTCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVNEQGICPRHQEALKLFCEVDEEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMKAKEERRVTELKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAANRLEEQAVQLSRLLAEAQERSQQGGLRLLQDIKETFNRCEEIQLQPPEIWSPDPCQPHSHDFLTDAIVRKMSRMFCQAARVDLTLDPDTAHPALLLSPDRRGVRLAERRQEVPEHSKRFSADCCVLGAQGFRSGRHYWEVEVGGRRGWAVGAARESTHHKEKVGSGGSSVSSGDASSSRHHHRRRRLHLPQQLLLQREVWCVGTHGKRYQAQSSTEQTLLSPCEKPRRFGVYLDYEAGRLGFYNADTLAHVHTFSAAFLGERVFPFFRVLSKGTRIKLCP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5NCC3-1", "uniprot_id": "TRI41_MOUSE", "id": "Q5NCC3-1", "name": "E3 ubiquitin-protein ligase TRIM41", "aln": "MAAVAMTPNPVQTLQEEAVCAICLDYFTDPVSIGCGHNFCRVCVTQLWGGEDEEDRDELDREEEEEEVGEEEEVEAVGAGGGWDTPMREEDYEGDMEEEAEEEEE-VFWSSGIGGSNWDNMDYVWEEEEEEEEEELDYYLGDVA--DLRGEDEDEEEEVLEEDEEEELDPITQLPPPPAPRRCFTCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVNEQGICPRHQEALKLFCEVDEEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMKAKEERRVTELKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAANRLEEQAAQLSRLLAEAQERSQQGGLRLLQDIKETFNRCEEIQLQPPEIWSPDPCQPHSHDFLTDAIVRKMSRMFCQAARVDLTLDPDTAHPALLLSPDRRGVRLAERRQEVPEHSKRFSADCCVLGAQGFRSGRHYWEVEVGGRRGWAVGAARESTHHKEKVGSGGSSVSSGDASSSRHHHRRRRLHLPQQLLLQREVWCVGTHGKRYQAQSSTEQTLLSPCEKPRRFGVYLDYEAGRLGFYNADTLAHVHTFSAAFLGERVFPFFRVLSKGTRIKLCP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WV44-1", "uniprot_id": "TRI41_HUMAN", "id": "Q8WV44-1", "name": "E3 ubiquitin-protein ligase TRIM41", "aln": "MAAVAMTPNPVQTLQEEAVCAICLDYFTDPVSIGCGHNFCRVCVTQLWGGEDEEDRDELDREEEEE-DGEEEEVEAVGAGAGWDTPMRDEDYEGDMEEEVEEEEEGVFWTSGMSRSSWDNMDYVWEEEDEEED--LDYYLGDMEEEDLRGEDEEDEEEVLEEVEEEDLDPVTPLPPPPAPRRCFTCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGICPKHQEALKLFCEVDEEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMKAKEERRVTELKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASRLAEQAAQLSRLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSPDPCQPHSHDFLTDAIVRKMSRMFCQAARVDLTLDPDTAHPALMLSPDRRGVRLAERRQEVADHPKRFSADCCVLGAQGFRSGRHYWEVEVGGRRGWAVGAARESTHHKEKVGPGGSSVGSGDASSSRHHHRRRRLHLPQQPLLQREVWCVGTNGKRYQAQSSTEQTLLSPSEKPRRFGVYLDYEAGRLGFYNAETLAHVHTFSAAFLGERVFPFFRVLSKGTRIKLCP", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****************************************************************** ************.*******:**********.***** ***:**:. *.***********:***: *******: *** ***::******* ***:***:* ***************************************************.:*****:*************************************************************************************************************************.** ***.*********************************:******:*********************************************:*****************.:*.************************************************.*****.********************* ***********:*****************.**********************:**********************************", "identical_positions": 589, "similar_positions": 30, "identity": "93.05%" }, { "cls_id": "homologset.agr.RGD:1308887", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BXR9-1", "uniprot_id": "OSBL6_MOUSE", "id": "Q8BXR9-1", "name": "Oxysterol-binding protein-related protein 6", "aln": "MSSDE-KGISPAHKTSTPTHRSASSSTSSQRESRQSIHVLERTASSSTEPSVSRQLLEPEPIPLSKEADSWEIIEGLKIGQTNVQKPDRHEGFMLKKRKWPLKGWHKRFFVLDNGMLKYSKAPLDIQKGKVHGSIDVGLSVMSIKKKAR-RIDLDTEEHIYHLKVKSQDWFDAWVSKLRHHRLYR-QNEIVRSPRDASFHIFPATSTAESSPAANVSVVDGKMQ--------------------PNSFPWQSPLPCSNSLPATCTTGQSKVAAWLQDSEE-----MDRCAEDLAHCQSNLVELSKLLQNLEILQRTQSAPNFTDMQANCVDISKKDKRVTRRWR---TKSVSKDTKIQLQEGPPAKGQFNTTRRRQRLAAAVATTVPFSATMSPVRLHSSNPN-LCADI-EFQTPPSHLTDPLESSTDYTK------LQEEFCLIAQKVHSLLKSAFNSIAIEKEKLKQVVSEQDHNKGHSTQMARLRQSLSQALNQNAELRSRLNRIHSES---TICDHVVSVNIIPSPDEPGEQ---IHVSLPLSQQVANESRLSMSESVSEFFDAQEVLLSASSSENEASDDES--YISDVSDNISEDNTSVADNISRQILNGELTGGAFRNGRRTCLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECIREDKGFRFFSEQVSHHPPISACHCESKNFVFWQDIRWKNKFWGKSMEILPVGTLNVTLPKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTLRNTKSSVCICKLTFVKVNYWNSNVNEVQGVVIDQEGKVVHRLFGKWHEGLYCGVAPSAKCIWRPGSLPTNYELYYGFTRFAVELNELDPVLKDLLPPTDARFRPDQRFLEEGNLEAAAAEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQREAWVSNDTYWELRKDPGFSKVDSPVLW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LMF4-1", "uniprot_id": "A0ABK0LMF4_RAT", "id": "A0ABK0LMF4-1", "name": "Oxysterol-binding protein", "aln": "MSSDE-KGISPAHKTSTPTHRSALSSTSSQRESRQSIHVLERTASSSTEPSISRQLLEPEPIPLSKEADSWEIIEGLKIGQTNVQKPDRHEGFMLKKRKWPLKGWHKRFFVLDNGMLKYSKAPLDIQKGKVHGSIDVGLSVMSIKKKAR-RIDLDTEEHIYHLKVKSQDWFDAWVSKLRHHRLYR-QNEIVRSPRDASFHIFPATSTAESSPAANVSVVDGKMQ--------------------PSSFPWQSPLPCSNSLPATCTTGQSKVAAWLQDSEE-----MDRCAEDLAHCQSNLVELSKLLQNLEILQRTQSAPNFTDMQANCVDISKKDKRVTRRWR---TKSVSKDTKIQLQEGPPAKGQFNTTRRRQRLAAAVATTVPFSATMSPVRLHSSNPN-LCADI-EFQTPPSHLTDPLESSTDYTK------LQEEFCLIAQKVHSLLKSAFNSIAIEKEKLKQMVSEQDHNKGHSTQMARLRQSLSQALNQNAELRSRLNRIHSES---TICDHVVSVNIIPSPDEPGEQ---IHANLPLSQQVVNESRLSMSESVSEFFDAQEVLLSASSSENEASDDES--YISDVSDNISEDNTSVADNISRQILNGELTGGAFRNGRRTCLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECIREDKGFRFFSEQVSHHPPISACHCESKNFVFWQDIRWKNKFWGKSMEILPVGTLNVTLPKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNVNEVQGVVIDQEGKVVHRLFGKWHEGLYCGVAPSAKCIWRPGSLPTNYELYYGFTRFAVELNELDPVLKELLPPTDARFRPDQRFLEEGNLEAAAAEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQREAWVSNDTYWELRKDPGFSKVDSPVLW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BZF3-1", "uniprot_id": "OSBL6_HUMAN", "id": "Q9BZF3-1", "name": "Oxysterol-binding protein-related protein 6", "aln": "MSSDE-KGISPAHKTSTPTHRSASSSTSSQRDSRQSIHILERTASSSTEPSVSRQLLEPEPVPLSKEADSWEIIEGLKIGQTNVQKPDKHEGFMLKKRKWPLKGWHKRFFVLDNGMLKYSKAPLDIQKGKVHGSIDVGLSVMSIKKKAR-RIDLDTEEHIYHLKVKSQDWFDAWVSKLRHHRLYR-QNEIVRSPRDASFHIFPSTSTAESSPAANVSVMDGKMQ--------------------PNSFPWQSPLPCSNSLPATCTTGQSKVAAWLQDSEE-----MDRCAEDLAHCQSNLVELSKLLQNLEILQRTQSAPNFTDMQANCVDISKKDKRVTRRWR---TKSVSKDTKIQLQ-------------------------VPFSATMSPVRLHSSNPN-LCADI-EFQTPPSHLTDPLESSTDYTK------LQEEFCLIAQKVHSLLKSAFNSIAIEKEKLKQMVSEQDHSKGHSTQMARLRQSLSQALNQNAELRSRLNRIHSES---IICDQVVSVNIIPSPDEAGEQ---IHVSLPLSQQVANESRLSMSESVSEFFDAQEVLLSASSSENEASDDES--YISDVSDNISEDNTSVADNISRQILNGELTGGAFRNGRRACLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECIREDKGFRFFSEQVSHHPPISACHCESKNFVFWQDIRWKNKFWGKSMEILPVGTLNVMLPKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNMNEVQGVVIDQEGKAVYRLFGKWHEGLYCGVAPSAKCIWRPGSMPTNYELYYGFTRFAIELNELDPVLKDLLPPTDARFRPDQRFLEEGNLEAAASEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQREAWVSNDTYWELRKDPGFSKVDSPVLW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BJS4-1", "uniprot_id": "A0A8M2BJS4_DANRE", "id": "A0A8M2BJS4-1", "name": "Oxysterol-binding protein", "aln": "MSRHQSRTTSLEEKVATPIHR----STAPLQKSSTPTHKSASSSSSSQRDSR-------------QEPDSWEIIEGLRIGQTHVQRPEKHEGFMLKKRKWPLKGWHKRFFVLDNGILKYSKSPVDIQKGKLHGSIDVGLSVMSIKKRAR-RIDLDTEEHIYHLKVKSPDVFDLWVCKLRHHRLFR-QNEIVRSPRDATLRTFPPSAGAESPQNTPSSTHPKKQGK-------------------PSSFPWQLPPSCSN--------GQSKVAAWLQESEE-----MDKCAEELAYCQSSLLELNQLLQSLEILQRTQSAPNFTDMQSNCVDLSKKEKRVSRRWR---TKSVSKDAKLQQQVQS--------------LPQSHSAKVPLSASMSQVRLHSSNPN-LCAELADFQAPVTRLTDGIDSAGDYIK------LQEDFCIIAQKVHSLLKSAFNTVAIEKEKIKQVLLDHEQ-TGQSNQIVTLRRSLSQALSQNAELKTRLNRIHSES---VLSEQVVSVNIISSPDEACEP---LHVGLPLSQQVSNESRLSMSESVSEFFDAQEVLLSASSSENEASDDES--YVSDVSDNISEDNASVTDNVSRQMPNGELASSMFRNGRRPCLPAPAPDTSNINLWNILKNNIGKDLSKVSMPVELNEPLNTLQHMCEELEYTELLDKAAQTDDPYERMAIVAAFAVSGYSSTYYRAGSKPFNPLLGETYECIREDKGFCFFSEQVSHHPPISACHCDSQNFTFWQDVRWKNKFWGKSMEILPIGTVNVMLPSYGDHYEWNKVTTCVHNILSGRRWIEHYGEVTIRNTRSTTCICKLSFIKGNYWSSNVNEVQGSVMDQEGRVIHRLFGKWHEGLYCGVPPSAKCIWRPGSMPTDYELYYGFTRFAVELNELFPEMKELLPPTDARFRPDQRFLEEGNVQMATAEKQRIEEQQRNRRKWMEENNIKHQPRFFKKVMDSNQRERWVSNSMYWELRKDPGFLKLENPELW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P38713-1", "uniprot_id": "OSH3_YEAST", "id": "P38713-1", "name": "Oxysterol-binding protein homolog 3", "aln": "METIDIQNRSFVVRWVKCGRGDVINYQIKPLKKSIEVGIYKKLKSSVDDHASAVHIAPDTKTLLDYTTKSLLHKGSSSNIEEHHRRSSQHSHSSSNGSDNKRKERSYSSLSISGIQQQSQEIPLREKLSASGFTLVKRVGNVSGNTMVQGDLEVKDTDYYYAFILDNSSSKNAKKKILFNASVINGDNQSMISTRSTPPARPTALSRTSTQQDMLFRVGQGRYLQGYLLKKRRKRLQGFKKRFFTLDFRYGTLSYYLNDHNQTCRGEIVISLSSVSANKKDKIIIIDSGMEVWVLKATTKENWQSWVDALQTCFDDQFEDKDTSTLEENPDILDDDKEVINKSSPQDHDHLTPTATTKSALSHRQHTQKDMDDIYVPLPSESYATFSMNLRLIQQRLEQCKKDSLSYKPTTLHQRSEGLNGTHSSSSVFTNNRVSSFNHSSSGMTSSDSLASEEVPSNKTYIEHALYNQLADLEVFVSRFVTQGEVLFKDHQILCKKAKDTRVSLTSYLSENDEFFDAEEEISRGVIILPDTEDDINNIVEETPLLGKSDQNEFTKEVQLSGSEQIASSSVESYTTNDENHSRKHLKNRHKNRRRGHPHHQKTKSAQSSTETFTSKDLFALSYPKSVTRRNDIPEAAASPPSLLSFLRKNVGKDLSSIAMPVTSNEPISILQLISETFEYAPLLTKATQRPDPITFVSAFAISFLSIYR-DKTRTLRKPFNPLLAETFELIREDMGFRLISEKVSHRPPVFAFFAEHLDWECSYTVTPSQKFWGKSIELNNEGILRLKFKTTGELFEWTQPTTILKNLIAGERYMEPVNEFEVHSSKGDKSHILFDKAGMFSGRSEGFKVSIIPPPSSNRKKETLAGKWTQSLAN--ETTHETIWEVGDLVSNPKKKYGFTKFTANLNEITEIEKGNLPPTDSRLRPDIRAYEEGNVDKAEEWKLKLEQLQRERR----NKGQDVEPKYFEKVSK-NEWKYITGPKSYWERRKKHDWSDIS--QLW", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. : : * : . : .. ** : ..* . : : ::..:*. : . * : :.. : .: *: : . :: :. :* :. .: :::. :: * : :.. . : * : : . :*: : *.*.:. .. : :.: . : . .* : * : :. .:: :* * . :. : .. :: *: * : *. : *: ..:*.* .: . :: :. : ..:. : **...: : *. . :: *.. .*: : : :.. : :.. : : . *. **: :*: . . .* * :. . .: : : *. **. .:. :* .:* ** : :. *.:. ** .:. * ** : :..* ::..**.: .. . : . .: .:::. ::. :. : . :* . : :. * . :* .* .:*::*:*****.::*** ***:. ** :.* :**: ** **:: ** : .* :* * *: *****:*.**:* **** ** ::**:***:**: * ..: :: : .:******:*: * :.: : . *: : *.: ** ::*:::*.*::* .*. ::.::. . : *: :*. ...: * *** :.* .: : **. *.: :: : ****:*: :***: * *****:*:*** * ****:: * * ::*: **.** ::. . *::*:** . *: : .. . *** **. .: .:. **", "identical_positions": 175, "similar_positions": 318, "identity": "17.4%" }, { "cls_id": "homologset.agr.RGD:1308888", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5BJS0-1", "uniprot_id": "DHX30_RAT", "id": "Q5BJS0-1", "name": "ATP-dependent RNA helicase DHX30", "aln": "-----------------------MFTLDSFRKDR-TQHRQRQCKLPPPRLPPMCVNP---APGGTISRASRDLLKEFPQPKNLLNSVIGRALGISHAKDKLVYVHTNGPKKKKVTLHIKWPKSVEVEGYGSKKIDAERQAAAAACQLFKGWGLLGPRNELFDAAKYRVLADRFGSPADSWWRPEPTMPPTSWRQLNPENIRPAGTGGLSRSLGREEEEDEEEELEEGTIDVTEFLSMTQQDSHNPLRDSRGGSFEMTDDDSAIRALTQFPLPKNLLAKVIQIATSSSTAKNLMQFHTVGTKTKLATLTLLWPCPMTFVAKGRRKAEAENKAAALACKKLKSLGLVDRNNEPLTHAMYNLASLRELGETQRRPCTIQVPEPILRKIEAFLSHYPVDSS--WISPELRLQSDDILPLGKDSGP---LSDPITGKPYMPLSEAEEVRLSQSLLELWRRRGPIWQEAPQLPVDPHRDTILSAIEQHPVVVISGDTGCGKTTRIPQLLLERYVTEGRGARCNVIITQPRRISAVSVAQRVSHELGPSLRRNVGFQVRLESKPPAR-GGALLFCTVGILLRKLQSNPSLEGVSHVIVDEVHERDVNTDFLLILLKGLQRLNPALRLVLMSATGDNERFSRYFGGCPVIKVPGFMYPVKEHYLEDILAK-------LGKHQY--PHRHRHHESEDECALDLDLVTDLVLHIDARGEPGGILCFLPGWQEIKGVQQRLQEALGMHESKYLILPVHSNIPMMDQKAIFQQPPLGVRKIVLATNIAETSITVNDIVHVVDSGLHKEERYDLKTKVSCLETVWVSRANVIQRRGRAGRCQSGFAYHLFPRSRLEKMVPFQVPEILRTPLENLVLQAKIHMPEKTAVEFLSKAVDSPNIKAVDEAVILLQEIGVLDQREYLTTLGQRLAHISTDPRLAKAIVLAAIFRCLHPLLVVVSCLTRDPFSSSLQNRAEVDKVKALLSHDSGSDHLAFVRAVAGWEEVLRWQDRTSRENYLEENLLYAPSLRFIHGLIKQFSENIYEAFLVGKPSDCTLPSAQCNEYSEEEELVKGVLMAGLYPNLIQVRQGKVTRQGKFKPNSVTYRTKSGNILLHKSTINREATRLRSRWLTYFMAVKSNGSVFVRDSSQVHPLAVLLLTDGDVHIRDDGRRATISLSDSDLLRLEGDSRTVRLLRELRRALGRMVERSLRSELAALPLSVQQEHGQLLALLAELLR-----------GPCGSFDVRKTADD--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99PU8-1", "uniprot_id": "DHX30_MOUSE", "id": "Q99PU8-1", "name": "ATP-dependent RNA helicase DHX30", "aln": "MVTPVCNSSTWQPKDSSFLSWPEMFSLDSFRKDR-TQHRQRQCKLPPPRLPPMCVNP---APGGTITRASRDLLKEFPQPKNLLNSVIGRALGISHAKDKLVYVHTNGPKKKKVTLHIKWPKSVEVEGYGSKKIDAERQAAAAACQLFKGWGLLGPRNELFDAAKYRVLADRFGSPADSWWRPEPTMPPTSWRQLNPENIRPGGPAGLSRSLGREEEEDEEEELEEGTIDVTEFLSMTQQDSHNPLRDSRGGSFEMTDDDSAIRALTQFPLPKNLLAKVIQIATSSSTAKNLMQFHTVGTKTKLATLTLLWPCPMTFVAKGRRKAEAENKAAALACKKLKSLGLVDRNNEPLTHAMYNLASLRELGETQRRPCTIQVPEPILRKIEAFLSHYPVDSS--WISPELRLQSDDILPLGKDSGP---LSDPITGKPYMPLSEAEEVRLSQSLLELWRRRGPIWQEAPQLPVDPHRDTILSAIEQHPVVVISGDTGCGKTTRIPQLLLERYVTEGRGARCNVIITQPRRISAVSVAQRVSHELGPSLRRNVGFQVRLESKPPAR-GGALLFCTVGILLRKLQSNPSLEGVSHVIVDEVHERDVNTDFLLILLKGLQRLNPALRLVLMSATGDNERFSRYFGGCPVIKVPGFMYPVKEHYLEDILAK-------LGKHQY--PHRHRHHESEDECALDLDLVTDLVLHIDARGEPGGILCFLPGWQEIKGVQQRLQEALGMHESKYLILPVHSNIPMMDQKAIFQQPPLGVRKIVLATNIAETSITVNDIVHVVDSGLHKEERYDLKTKVSCLETVWVSRANVIQRRGRAGRCQSGFAYHLFPRSRLEKMVPFQVPEILRTPLENLVLQAKIHMPEKTAVEFLSKAVDSPNIKAVDEAVILLQEIGVLDQREYLTTLGQRLAHISTDPRLAKAIVLAAIFRCLHPLLVVVSCLTRDPFSSSLQNRAEVDKVKALLSHDSGSDHLAFVRAVAGWEEVLRWQDRTSRENYLEENLLYAPSLRFIHGLIKQFSENIYEAFLVGKPSDCTLPSAQCNEYSEEEELVKGVLMAGLYPNLIQVRQGKVTRQGKFKPNSVTYRTKSGNILLHKSTINREATRLRSRWLTYFMAVKSNGSVFVRDSSQVHPLAVLLLTDGDVHIRDDGRRATISLSDSDLLRLEGDSRTVRLLREFRRALGRMVERSLRSELAALPLSVQQEHGQLLALLAELLR-----------GPCGSFDMRKTADD--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7L2E3-1", "uniprot_id": "DHX30_HUMAN", "id": "Q7L2E3-1", "name": "ATP-dependent RNA helicase DHX30", "aln": "-----------------------MFSLDSFRKDR-AQHRQRQCKLPPPRLPPMCVNP---TPGGTISRASRDLLKEFPQPKNLLNSVIGRALGISHAKDKLVYVHTNGPKKKKVTLHIKWPKSVEVEGYGSKKIDAERQAAAAACQLFKGWGLLGPRNELFDAAKYRVLADRFGSPADSWWRPEPTMPPTSWRQLNPESIRPGGPGGLSRSLGREEEEDEEEELEEGTIDVTDFLSMTQQDSHAPLRDSRGSSFEMTDDDSAIRALTQFPLPKNLLAKVIQIATSSSTAKNLMQFHTVGTKTKLSTLTLLWPCPMTFVAKGRRKAEAENKAAALACKKLKSLGLVDRNNEPLTHAMYNLASLRELGETQRRPCTIQVPEPILRKIETFLNHYPVESS--WIAPELRLQSDDILPLGKDSGP---LSDPITGKPYVPLLEAEEVRLSQSLLELWRRRGPVWQEAPQLPVDPHRDTILNAIEQHPVVVISGDTGCGKTTRIPQLLLERYVTEGRGARCNVIITQPRRISAVSVAQRVSHELGPSLRRNVGFQVRLESKPPSR-GGALLFCTVGILLRKLQSNPSLEGVSHVIVDEVHERDVNTDFLLILLKGLQRLNPALRLVLMSATGDNERFSRYFGGCPVIKVPGFMYPVKEHYLEDILAK-------LGKHQY--LHRHRHHESEDECALDLDLVTDLVLHIDARGEPGGILCFLPGWQEIKGVQQRLQEALGMHESKYLILPVHSNIPMMDQKAIFQQPPVGVRKIVLATNIAETSITINDIVHVVDSGLHKEERYDLKTKVSCLETVWVSRANVIQRRGRAGRCQSGFAYHLFPRSRLEKMVPFQVPEILRTPLENLVLQAKIHMPEKTAVEFLSKAVDSPNIKAVDEAVILLQEIGVLDQREYLTTLGQRLAHISTDPRLAKAIVLAAIFRCLHPLLVVVSCLTRDPFSSSLQNRAEVDKVKALLSHDSGSDHLAFVRAVAGWEEVLRWQDRSSRENYLEENLLYAPSLRFIHGLIKQFSENIYEAFLVGKPSDCTLASAQCNEYSEEEELVKGVLMAGLYPNLIQVRQGKVTRQGKFKPNSVTYRTKSGNILLHKSTINREATRLRSRWLTYFMAVKSNGSVFVRDSSQVHPLAVLLLTDGDVHIRDDGRRATISLSDSDLLRLEGDSRTVRLLKELRRALGRMVERSLRSELAALPPSVQEEHGQLLALLAELLR-----------GPCGSFDVRKTADD--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7TE51-1", "uniprot_id": "A0A8N7TE51_DANRE", "id": "A0A8N7TE51-1", "name": "ATP-dependent RNA helicase DHX30", "aln": "-----------MAMSSALTPLRALLSLRSKTLEINKDIRSRWAFIRQYRSKPDVVHTRRHSPPETINKAHPDYL----HAKNLLYNTLSRSVGLSNVSQYLKFSCTDG-EVKRATVTLLWPVRIETEGFGSRKQEAERNAAAAALQKLCELGVYAPGK----------------------RRQE---------------------AGMLRMKDRQTSLCDNE--EENHLQSLPIQKKTQKDRAHGLVE---------EDSRLSEALAIFPRPRTLLGSVIQVATSSCRVRDLLQYKTSGGKVKVCELNVLWPTPMTFTASGRRRLEAEANAAALACLKLKELNLLDEQNKPLTHARYHQDQVREAGERHRQPCRMQIPEQLELRIQQYLSQYPVEAEVQKLWDEEEHQSSSISTAADDYDEDEFITDAITSKPYRALEPKEAEHLSQRLLSMWKRVGPAR--GAELPVDAHKESILEAVRSSQVVVISGETGCGKTTRIPRFLLEDGVLRGEGAECNVLVTQPRRISAVSVAQRVAHEIGPALQHCVGYQVRLESRPPERSGGALLFLTLGVLLKKLQSNPRLEGISHVIVDEVHERDVQTDLLLHLLRCVLSLRPELKVLLMSASGDSQRLAQYFGGCPVLRVPGFMHPVRARFLEDMQLDSRRPLLDMGSTQWSAEVRGRMGKEENNVTPDLDLVADVIDHIHRTGEPGAVLCFLPGWQEIKAVQQQLEEKQAYRSGSQIILPLHSSMAVSEQQVVFQRPPAGQRKIVLATNIAETSITIDDIVHVVDAGVQKEQNYDPRTKVSALNTVWISQANVTQRRGRAGRCQPGHSYHLFPRKQLERMEPFPVPEILRTPLESVVMQAKIHCPESKAEDFLSQVLDSPDTQAVRTAVKNLMDIGVLDASEDLTPLGHHVSCMSCDPRLGKVLVFSALFSCVQPVLSVVACLTRDPFYNSLQNRTLVSKAKAELSGSSGSDYLVFSRVVQSWREQH---SRDSRQDYLDKHTLSGASLRFIHGLMQQFSDNLCEAGLVDHSAECLRLSSPVNQQSKEEQLITAVLLAGLYPNLIQVKKGVVTKSGRFRAENVSFRTESGPVLLHRSSVNRDKQHLWSRWLTFFSAVKSSGQVFIRDSTVVHPLALLLLTDCDLSERVVGDRVEVALPGPALIRWEFSPAVWELLWDLRASIQAMIYRKLR-QSECKSSSEQRKDSELIDLLVDLLNNTDPDVSRDQEDALNSSNTENAEADSC", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :::* * : : *.* . : * * *:. :* **.:* * * :.**** ..:.*::*:*:..: * : *:* : *:.*: : ** :*.**:**:* :***:***** * : *: .* : * * .*: * .*: . ::* **. :: : . **:* * : :*. .**: ** *:.**..***:****. .::*:*::* * *.*:. *.:*** ****.*.***: *** :****** ***.*.*:*.:*:***** *: .:** ** :*:** :*:** : :*: :*.:***::. : * . **..* . ..* . ::*.**.*** .* * :*** **.:*:* ** ..:****.*:::**.*:.. ******:**********::*** * .*.**.***::***************:**:**:*:: **:******:** * ****** *:*:**:****** ***:*************:**:** **: : *.* *:::****:**.:*:::*******::*****:**: ::***: . :*. *: * * :.*:: : *****:*:: **. ****.:***********.***:*:* . :... :***:**.:.: :*:.:**:** * ***************::*******:*::**:.** :****.*:***:*:*** **********.*.:******.:**:* ** **********.:*:***** **..* :***:.:***: :** ** * :***** * **.**:::: :* ****.*.:*::*:* *::*:* **:******* .*****: *.*.** ** .****:*.* *.* .*.* .* **::**::: * ..********::***:*: ** **.:.::* *: *: *:**:*:..**:**********::* **:.*:*:.:.*::**:** :***:*::**: :* *****:* ****.*.**:***: *****:***** *: * * *. ::*... *:* * .. . .** ::* :: *: *.** : . . * *.:..:*: **.:**. .. .* : .:: * ", "identical_positions": 573, "similar_positions": 348, "identity": "45.88%" }, { "cls_id": "homologset.agr.RGD:1308889", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZPP7-1", "uniprot_id": "A0A8I5ZPP7_RAT", "id": "A0A8I5ZPP7-1", "name": "Laminin subunit alpha-2", "aln": "---MESMCAHKQCYLESRILSHCFRAGKENIHRQRSAQRIHFRYFSNFPQRIKMKFYVKTTLYIGPAAHFNWVDPRQQLRGLQRSGSAPARMPAAGGILLLLLLGILEGSQTQRPQQRRQSPAHQQRG------------------------LFPAVLNLASNALITTNATCGEKGPEMYCKLVEHVPGQPVRNPQCRICNQNSSHPYQRHPITNAIDG--KNTWWQSPSIKNGVEYHYVTITLDLQQVFQIAYVIVKAANSPRPGNWILERSLDDEEYKPWQYHAVTDTECLTLYNIYPRTGPPSYAKDDEVICTSFYSKIHPLENGEIHISLINGRPSADDPSPELLEFTSARYIRLRFQRIRTLNADLMMFAHKDPREIDPIVTRRYYYSVKDISVGGMCICYGHARACPLDPATNKSRCECEHNTCGESCDRCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDETVASRNLSLNIHGKYIGGGVCINCTHNTAGINCETCIDGFFRPKGVSPSYPRPCQPCHCDPAGSLSEVCIKDEKHTRRGLKPGSCYCKPGFGGMNCDRCVRGYRGYPDCQPCNCSGLGST-NQDPCIGPCSCKENVEGEDCSHCKFGFFNLQEENQKGCEECFCSGVSDRCQSSYWTYGNIQDMHGWYLTDLSGRIQVAPQLDNPDAPQQISVSNSEARRSLPDSYYWSAPAPYLRNKLPAVGGQLSFTISYDLEEEEDDTEKILQLMIILEGNN-------------LRISTAYKEVHLEPSEEHVEELSLKEESFTIHGTNLP---VSRKDFMILLTNLERVLIQTTYNLGMDVIFRLSSVNLESAVPYPTDRSIASAVEVCQCPPGYSGSSCEACWPRHRRVNG----TIFGGLCEPCQCFGHAEACNDVTGECLSCKDHTGGPYCNECLPGFYGDPTRGTSEDCQPCACPLNIPSNNFSPTCHLDRS--------------LGLICDECPVGYTGPRCERCAEGYFGQPSIPGGSCQPCLCN------------------------------------------DNLDFSIPGSCDSLSGSCLI-----------------------------------------------CKPGTTGRFCELCADGYFGD----------------------------------AVDAKNCQPCRCNVNGSFSEICHRKTGQCECRPNVQGQRCDECKPETFGLQLGRGCIPCNCNSFGSKSFDCE-ASGQCWCQPGVAGKKCDRCAHGYFNFQEGGCTACDCS-HLGNNCNPKTGQCICPPNTIGEKCSECLPNTWGHSIVTGCKVCNCSTVGSLSSQCNINTGQCSCHPKFSGMKCSECNRGHWNYPLCSLCDCFLPGTDATTCDSETRKCSCSDQTGQCTCKVNVEGVHCDRCRPGKFGLEAKNPLGCSSCYCFGVTSQCSEAKG----------------LVRTWVTLRDEQTILPLVDEALQHTTTKGIAFQ-------NPEIVAKMDEVRQDLHLEPFYWKLPEQFEGKKLMAYGGKLKYTIYFEARDETGFATYKPQVIIRGGTPTHARIITRHMAAPLIGQLTR-HEIEMTEKEWKYYGDDPRISRTVTREDFLDILYDIHYILIKATYGNVVRQSRISEISMEGAEPGQVSAASPLANLIERCDCPPGYSGLSCETCAPGFYRVH--SEPGGRTPGPTLGTCVPCQCHGHSSQCDPETSVCQNCQHHTAGDFCERCALGYYGIVRGLPNDCQPCACPLISPSNNFSPSCVLEGLEDYRCTACPRGYEGQYCERCAPGYAGSPS-SPGGSCQECECDPYGSLPVPCDPVTGLCTCRPGATGRKCDGCEHGHAREGAECVFCGDECTGLLLGDLAHLEQMAMN----INLTGPLPAPYKILYGLENATQELKHLLSPQRAPERLLQLAEGNMNTLVMEMNELLTRATKVTADGEQTGQDAERTNSRAQSLEEFIKGLVQHAEAVNEKAIKLNETLGSQDRTAERNLQELQKEIDRMLKELRSKDLQTQKEVAEDELVAAEGLLKRVNKLFGEPRAQNEEMEKDLREKLAEYQNKLDDAWDLLREATKKTKDADRLSAANQKNMTILETKKEAIEGSKRQIENTLKEGNDILDEANRLAGEITSVIDYVEDIKTKLPPMSEELSDKIDDLAQEIKDRRLAEKVFQAESHAAQLNDSSAVLDGILDEAKNISFNATAAFRAYSNIKDYIDEAEKVAREAKELAHEATKLATSPQG-LLKEDAKGSLQKSFRILNEAKKLANDVKENHNDLSGLKTRLETADLRNSGLLGALNDTMDKLSAIPN-DTAAKLQAVKEKAREANDTAKAVLAQVKDLHQNLDGLKQNYNKLADSVAKTNAVVKD--PSKN--IADAGATVRNLEQEADRLIDKLKPIKELEDNLKKNISEIKELINQARKQANSIKVSVSSGG-DCIRTYKPEIKKGSYN---NIVVHVKTAVADNLLFYLGSAKFIDFLAIEMRKGKVSFLWDVGSGVGRVEYPDLTID-----DSYWYRIEASRTGRNGSISVRALD--GPKASMVPSTHHSVSPPGYTILDVDANAMLFVGGLTGKIKKADAVRVTTFTGCMGETYFDNKPIGLWNFREKEGDCKGCTVSPQVEDSEGTIQFD---GEGYALVSRPIRWYPNISTVMFKFRTFSSNALLMYLATRDLKDFMSVELSDGHVKVSYDLG-SGMASVVSNQNHNDGKWKSFTLS---RIQKQANISIVDIDSNQEENIATSSSGNNFGLDLKADDKIYFGGLPTLRNL----RPEVNVKKYSGCLKDIEISRTPYNILSSPNYVGVTKGCSLENVYTVSFPKPGFVELAAVSIDVGTEINLSFSTRNESGIILLGSGGTLTPPRRKRRQTTQAYYAIFLNKGRLEVHLSSGTRTMRKIVIKPEPNLFHDGREHSVHVERTRGVFTVQVDENRRHMQNLTEE-----QPIEVKKLFVGGAPPEFQPSPLR-NIPAFQGCVWNLVINSIPMDFAQPIAFKNADIGRCAYQKPREEEDDAVPAEVTVQPQPVPTPAFPFPAPTMVHGPCVAESEPAFLSGSKQFGLSRNSHIALAFDDTKVKNR-LTIELEVRTEAESGLLFYMARIN-HADFATVQLRNGFPYFSYDLGSGDTSTMIPTRINDGQWHKIKITRVKQEGILSVDDASNQTISPKKADILDVVG---ILYVGGLPIN--YTTRRIGPVTYSLDGCVRNLYMEQAPVDLDQPTSSFHVGTCFANAEKGTYFDGTGFAKAVGGFKVGLDLLVEFEFRTTRPTGVLLGVSSQK-MDGMGIEMIDEKLMFHVDNGAGR-FTAVYDAGSPGHMCDGRWHKVTAKKIKNRLELVVDGNQVDAQSPNAAST-SADTNDPVFVGGFPDGLNQFGLTTNVRFRGCIRSLKLTKGTGKPLEVNFAKALELRGVQPVSCPTT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60675-1", "uniprot_id": "LAMA2_MOUSE", "id": "Q60675-1", "name": "Laminin subunit alpha-2", "aln": "------------------------------------------------------------------------------------------MPAATAGILLLLLLGTLEGSQTQR----RQSQAHQQRG------------------------LFPAVLNLASNALITTNATCGEKGPEMYCKLVEHVPGQPVRNPQCRICNQNSSNPYQRHPITNAIDG--KNTWWQSPSIKNGVEYHYVTITLDLQQVFQIAYVIVKAANSPRPGNWILERSLDDVEYKPWQYHAVTDTECLTLYNIYPRTGPPSYAKDDEVICTSFYSKIHPLENGEIHISLINGRPSADDPSPELLEFTSARYIRLRFQRIRTLNADLMMFAHKDPREIDPIVTRRYYYSVKDISVGGMCICYGHARACPLDPATNKSRCECEHNTCGESCDRCCPGFHQKPWRAGTFLTKSECEACNCHGKAEECYYDETVASRNLSLNIHGKYIGGGVCINCTHNTAGINCETCVDGFFRPKGVSPNYPRPCQPCHCDPTGSLSEVCVKDEKYAQRGLKPGSCHCKTGFGGVNCDRCVRGYHGYPDCQPCNCSGLGST-NEDPCVGPCSCKENVEGEDCSRCKSGFFNLQEDNQKGCEECFCSGVSNRCQSSYWTYGNIQDMRGWYLTDLSGRIRMAPQLDNPDSPQQISISNSEARKSLLDGYYWSAPPPYLGNRLPAVGGQLSFTISYDLEEEEDDTEKILQLMIIFEGND-------------LRISTAYKEVYLEPSEEHIEEVSLKEEAFTIHGTNLP---VTRKDFMIVLTNLERVLMQITYNLGMDAIFRLSSVNLESAVPYPTDRRIATDVEVCQCPPGYSGSSCETCWPRHRRVNG----TIFGGICEPCQCFAHAEACDDITGECLNCKDHTGGPYCNECLPGFYGDPTRGSPEDCQPCACPLNIPSNNFSPTCHLDRS--------------LGLICDECPIGYTGPRCERCAEGYFGQPSIPGGSCQPCQCN------------------------------------------DNLDYSIPGSCDSLSGSCLI-----------------------------------------------CKPGTTGRYCELCADGYFGD----------------------------------AVNAKNCQPCRCNINGSFSEICHTRTGQCECRPNVQGRHCDECKPETFGLQLGRGCLPCNCNSFGSKSFDCE-ASGQCWCQPGVAGKKCDRCAHGYFNFQEGGCIACDCS-HLGNNCDPKTGQCICPPNTTGEKCSECLPNTWGHSIVTGCKVCNCSTVGSLASQCNVNTGQCSCHPKFSGMKCSECSRGHWNYPLCTLCDCFLPGTDATTCDLETRKCSCSDQTGQCSCKVNVEGVHCDRCRPGKFGLDAKNPLGCSSCYCFGVTSQCSEAKG----------------LIRTWVTLSDEQTILPLVDEALQHTTTKGIAFQ-------KPEIVAKMDEVRQELHLEPFYWKLPQQFEGKKLMAYGGKLKYAIYFEARDETGFATYKPQVIIRGGTPTHARIITRHMAAPLIGQLTR-HEIEMTEKEWKYYGDDPRISRTVTREDFLDILYDIHYILIKATYGNVVRQSRISEISMEVAEPGHVLAGSPPAHLIERCDCPPGYSGLSCETCAPGFYRLR--SEPGGRTPGPTLGTCVPCQCNGHSSQCDPETSVCQNCQHHTAGDFCERCALGYYGIVRGLPNDCQPCACPLISPSNNFSPSCVLEGLEDYRCTACPRGYEGQYCERCAPGYTGSPS-SPGGSCQECECDPYGSLPVPCDRVTGLCTCRPGATGRKCDGCEHWHAREGAECVFCGDECTGLLLGDLARLEQMTMN----INLTGPLPAPYKILYGLENTTQELKHLLSPQRAPERLIQLAEGNVNTLVMETNELLTRATKVTADGEQTGQDAERTNSRAESLEEFIKGLVQDAEAINEKAVQLNETLGNQDKTAERNLEELQKEIDRMLKELRSKDLQTQKEVAEDELVAAEGLLKRVNKLFGEPRAQNEDMEKDLQQKLAEYKNKLDDAWDLLREATDKTRDANRLSAANQKNMTILETKKEAIEGSKRQIENTLKEGNDILDEANRLLGEINSVIDYVDDIKTKLPPMSEELSDKIDDLAQEIKDRRLAEKVFQAESHAAQLNDSSAVLDGILDEAKNISFNATAAFRAYSNIKDYIDEAEKVAREAKELAQGATKLATSPQG-LLKEDAKGSLQKSFRILNEAKKLANDVKGNHNDLNDLKTRLETADLRNSGLLGALNDTMDKLSAITN-DTAAKLQAVKEKAREANDTAKAVLAQVKDLHQNLDGLKQNYNKLADSVAKTNAVVKD--PSKNKIIADAGTSVRNLEQEADRLIDKLKPIKELEDNLKKNISEIKELINQARKQANSIKVSVSSGG-DCVRTYRPEIKKGSYN---NIVVHVKTAVADNLLFYLGSAKFIDFLAIEMRKGKVSFLWDVGSGVGRVEYPDLTID-----DSYWYRIEASRTGRNGSISVRALD--GPKASMVPSTYHSVSPPGYTILDVDANAMLFVGGLTGKIKKADAVRVITFTGCMGETYFDNKPIGLWNFREKEGDCKGCTVSPQVEDSEGTIQFD---GEGYALVSRPIRWYPNISTVMFKFRTFSSSALLMYLATRDLKDFMSVELSDGHVKVSYDLG-SGMTSVVSNQNHNDGKWKAFTLS---RIQKQANISIVDIDSNQEENVATSSSGNNFGLDLKADDKIYFGGLPTLRNLSMKARPEVNVKKYSGCLKDIEISRTPYNILSSPDYVGVTKGCSLENVYTVSFPKPGFVELAAVSIDVGTEINLSFSTRNESGIILLGSGGTLTPPRRKRRQTTQAYYAIFLNKGRLEVHLSSGTRTMRKIVIKPEPNLFHDGREHSVHVERTRGIFTVQIDEDRRHMQNLTEE-----QPIEVKKLFVGGAPPEFQPSPLR-NIPAFQGCVWNLVINSIPMDFAQPIAFKNADIGRCTYQKPREDESEAVPAEVIVQPQPVPTPAFPFPAPTMVHGPCVAESEPALLTGSKQFGLSRNSHIAIAFDDTKVKNR-LTIELEVRTEAESGLLFYMARIN-HADFATVQLRNGFPYFSYDLGSGDTSTMIPTKINDGQWHKIKIVRVKQEGILYVDDASSQTISPKKADILDVVG---ILYVGGLPIN--YTTRRIGPVTYSLDGCVRNLHMEQAPVDLDQPTSSFHVGTCFANAESGTYFDGTGFAKAVGGFKVGLDLLVEFEFRTTRPTGVLLGVSSQK-MDGMGIEMIDEKLMFHVDNGAGR-FTAIYDAGIPGHMCNGQWHKVTAKKIKNRLELVVDGNQVDAQSPNSAST-SADTNDPVFVGGFPGGLNQFGLTTNIRFRGCIRSLKLTKGTGKPLEVNFAKALELRGVQPVSCPTT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P24043-1", "uniprot_id": "LAMA2_HUMAN", "id": "P24043-1", "name": "Laminin subunit alpha-2", "aln": "------------------------------------------------------------------------------------------MPGAAGVLLLLLLSGGLGGVQAQRPQQQRQSQAHQQRG------------------------LFPAVLNLASNALITTNATCGEKGPEMYCKLVEHVPGQPVRNPQCRICNQNSSNPNQRHPITNAIDG--KNTWWQSPSIKNGIEYHYVTITLDLQQVFQIAYVIVKAANSPRPGNWILERSLDDVEYKPWQYHAVTDTECLTLYNIYPRTGPPSYAKDDEVICTSFYSKIHPLENGEIHISLINGRPSADDPSPELLEFTSARYIRLRFQRIRTLNADLMMFAHKDPREIDPIVTRRYYYSVKDISVGGMCICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPDCKACNCSGLGSK-NEDPCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFCSGVSNRCQSSYWTYGKIQDMSGWYLTDLPGRIRVAPQQDDLDSPQQISISNAEARQALPHSYYWSAPAPYLGNKLPAVGGQLTFTISYDLEEEEEDTERVLQLMIILEGND-------------LSISTAQDEVYLHPSEEHTNVLLLKEESFTIHGTHFP---VRRKEFMTVLANLKRVLLQITYSFGMDAIFRLSSVNLESAVSYPTDGSIAAAVEVCQCPPGYTGSSCESCWPRHRRVNG----TIFGGICEPCQCFGHAESCDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRS--------------LGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCN------------------------------------------DNLDFSIPGSCDSLSGSCLI-----------------------------------------------CKPGTTGRYCELCADGYFGD----------------------------------AVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARGCVPCNCNSFGSKSFDCE-ESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECS-HLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSCYCFGTTTQCSEAKG----------------LIRTWVTLKAEQTILPLVDEALQHTTTKGIVFQ-------HPEIVAHMDLMREDLHLEPFYWKLPEQFEGKKLMAYGGKLKYAIYFEAREETGFSTYNPQVIIRGGTPTHARIIVRHMAAPLIGQLTR-HEIEMTEKEWKYYGDDPRVHRTVTREDFLDILYDIHYILIKATYGNFMRQSRISEISMEVAEQGRGTTMTPPADLIEKCDCPLGYSGLSCEACLPGFYRLR--SQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPG-NPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCDGCKHWHAREGWECVFCGDECTGLLLGDLARLEQMVMS----INLTGPLPAPYKMLYGLENMTQELKHLLSPQRAPERLIQLAEGNLNTLVTEMNELLTRATKVTADGEQTGQDAERTNTRAKSLGEFIKELARDAEAVNEKAIKLNETLGTRDEAFERNLEGLQKEIDQMIKELRRKNLETQKEIAEDELVAAEALLKKVKKLFGESRGENEEMEKDLREKLADYKNKVDDAWDLLREATDKIREANRLFAVNQKNMTALEKKKEAVESGKRQIENTLKEGNDILDEANRLADEINSIIDYVEDIQTKLPPMSEELNDKIDDLSQEIKDRKLAEKVSQAESHAAQLNDSSAVLDGILDEAKNISFNATAAFKAYSNIKDYIDEAEKVAKEAKDLAHEATKLATGPRG-LLKEDAKGCLQKSFRILNEAKKLANDVKENEDHLNGLKTRIENADARNGDLLRTLNDTLGKLSAIPN-DTAAKLQAVKDKARQANDTAKDVLAQITELHQNLDGLKKNYNKLADSVAKTNAVVKD--PSKNKIIADADATVKNLEQEADRLIDKLKPIKELEDNLKKNISEIKELINQARKQANSIKVSVSSGG-DCIRTYKPEIKKGSYN---NIVVNVKTAVADNLLFYLGSAKFIDFLAIEMRKGKVSFLWDVGSGVGRVEYPDLTID-----DSYWYRIVASRTGRNGTISVRALD--GPKASIVPSTHHSTSPPGYTILDVDANAMLFVGGLTGKLKKADAVRVITFTGCMGETYFDNKPIGLWNFREKEGDCKGCTVSPQVEDSEGTIQFD---GEGYALVSRPIRWYPNISTVMFKFRTFSSSALLMYLATRDLRDFMSVELTDGHIKVSYDLG-SGMASVVSNQNHNDGKWKSFTLS---RIQKQANISIVDIDTNQEENIATSSSGNNFGLDLKADDKIYFGGLPTLRNLSMKARPEVNLKKYSGCLKDIEISRTPYNILSSPDYVGVTKGCSLENVYTVSFPKPGFVELSPVPIDVGTEINLSFSTKNESGIILLGSGGTPAPPRRKRRQTGQAYYAILLNRGRLEVHLSTGARTMRKIVIRPEPNLFHDGREHSVHVERTRGIFTVQVDENRRYMQNLTVE-----QPIEVKKLFVGGAPPEFQPSPLR-NIPPFEGCIWNLVINSVPMDFARPVSFKNADIGRCAHQKLREDEDGAAPAEIVIQPEPVPTPAFPTPTPVLTHGPCAAESEPALLIGSKQFGLSRNSHIAIAFDDTKVKNR-LTIELEVRTEAESGLLFYMARIN-HADFATVQLRNGLPYFSYDLGSGDTHTMIPTKINDGQWHKIKIMRSKQEGILYVDGASNRTISPKKADILDVVG---MLYVGGLPIN--YTTRRIGPVTYSIDGCVRNLHMAEAPADLEQPTSSFHVGTCFANAQRGTYFDGTGFAKAVGGFKVGLDLLVEFEFRTTTTTGVLLGISSQK-MDGMGIEMIDEKLMFHVDNGAGR-FTAVYDAGVPGHLCDGQWHKVTANKIKHRIELTVDGNQVEAQSPNPAST-SADTNDPVFVGGFPDDLKQFGLTTSIPFRGCIRSLKLTKGTGKPLEVNFAKALELRGVQPVSCPAN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8IP51-1", "uniprot_id": "Q8IP51_DROME", "id": "Q8IP51-1", "name": "", "aln": "MQIGNFIKWPLGLILILLVTHCQAKRQRKRLRGFSTAKDLQDYSMPLNDNSTELQQNIVSWTGARIASSPDKKKKSPQSSRRHKTKSGLIIESNIADSESMLAIASSESVTKKKPPQRRRNGKLQKSGGGAGGGALRLLKTEDVYSSSFSGGLYPPLFNVVPRAQISVNATCGQNGAEEYCKQVGAKPCGICNAHSSDRAKQRSIQSLISSGSGSGSGSGFEEGWWQSPTLQGGRQFEYVTILLDLKQTFQIFSVWLKSANSPRPASWILEKSLDGINFEPWQYFGLSDADCQRRWNLSGQNGKYVFQNDTEIICSTQFSKPGPLENGVLHASLLKNRPGATDQSPELMKFITTRYIRIRLQGMHSTANQDNSLDWLLD---SPSLEKHSFYSLSQLKVSARLDCNGHANRSHESPDDPLMQCICQHNTCGAQCEQCCPLFQDRPYQMG-----GECEICQCYGHAESCTYDP--------------FLDKGICQSCSNNTAGIECEFCEMGFYR--ELDAPLTDPCLPCSCNPARSTGGCQSDG----------GSCNCLEGFQGKNCEECAPGYYG-DDCKRCECDERGSLGSTGSCSGVCQCKLNVEGSTCSECAPGYFDLSAENAEGCTSCWCSGVSQTCHSAKLQTLAFETLNDWKITDIQRVKPISIPVDAETNRLIFAN-----ELDEVEAIYWQASLGYLGNRLTSYGSRLQLVLSWDVIRGDRSGKPTTGPNVILVGKNGLKIAFGDESLDGLGINLNVTLTEVGWYHVPPTVVDIKTRLRRTEGGDYHGESVTRSQFLSVLVSLDAVLIRAAFHTDQGETSLERAVIYSGGVELGGKS--SSQVEQCLCPAGYTGLSCEGCAFGFKRIYENTSDHQILSKCIPCPCNGHSNSCDLQSGNCGDCMHNTFGDRCERCQLGYYGNPLQGTPNDCKRCACPLSEDSNNFSPSCQLKSYNYMDLNPQFELIEHAEYICTQCPEGYTGDHCQVCDDGYFGNPRQPGSSCQRCDCAGGPCNVTTGECITCRGNTEGWHCERCKLGYWGDPAVGCDPCHCHTEGSESGLCDSTDGQCLCKPRYAGQKCDECDVGYANVELRCPSCNCDPLGSLVQDRCDPHTGQCHCKEGVMGAKCHECQDGYFGMNAVAYRMDDLAALRQNSDSDDDEWELVPDTEDPNSESTVACEECHCSSVGSLSSDCDKRTGQCACLANVTGRRCDKCRPGHWNLTAGEGCRDCRCDPHGSRGHECNPWTGQCDCKIGVGGQHCNECTEGFFGFSTEGCQRCSACRSEGQVCDPHNGRCICPKFTRGLGCGQCVPGTWGWQARLGCRECECDHIGSIGQQCSTGDGQCQCREGYSGRKCDTCAIGYFGYPECRRCGCDAEG-----SFTQADGSIACDSNGQCPCKSLVVGLKCDTCMQSTFGLSAQNPEGCTRCFCFGRSGECEQSDLSWGHIRMAESRNLSVQQIRPHSVPSSDYEYIVVVQMEGSSFHREDAEIQRMNDLSLVPKSTGNVSIGAYGQFYHPLYFQLPPQFYGDRTSSYGGFLYFTLITEGAHKPLERNILGQYPLVQLHAHSKLLLDFYEYEEFEYSLNVTHRVPLHESFWKYH----HTSQAVDRNTLMAALQNIRHIFIRAFAFADFQEVVLQNVHMDAAIYIKGSTN-LIAKGVERCKCPKRFDGLSCQDPGRSFYRWRNTTIVESVFIEDLIGRAAPCHCNGRSSDCDRETGVCQNCRGNTGGDHCHQCAEGFYGDPN-SPHGCQACPCPETN--RNFARGCNVWDGEVS--CVCKPGYTGRLCERCQAGYFGDPMRYPNTTCQPCNCHPDGIQTEGCDVETGRCYCREGVTGLKCDKCQAERHHLVDNGCKICDNCTLLLLDYMELVGNKLRRGMHNMDLTG-IPAPYRKLSEYESAYEKWNGRHWDFSQTKRRLQDYDSADILKLEAHAENLKFQSRKAVATIGKREFAIKSMREDAVTQQHSVGLLR-----SEILQTLSDLHGYGKSAHYLSLPTALKQARFYLQAIREHDQMVQGIRSTNDCAWKHFYAMGN---ASDASFDESGRLEMLWRDLNQTNHRVVDMRLQVDRVQEVENEAEDVLEHVRNLSIRVGESHQELDELNQRISDHLDPG--YLEQGEGLLRLTVQRQIMLNGHLNQLDGYRILLNTTLGVKTEQQRE-VRKHWLPKAEKHASHLLARSNEYARKFQPTRNGARIAMLASSAHSNITEAINDARLASILAKERVYEAQRTLYPSDGSSMIERAKHSLHRSKQLQQEALKQMHKSNVLKDKLHRQEQQVEGIKSTIYDSGLRTNNISGQLQGLSDGSARRQAKDSLEMADRTGEQMRAELQKAKDMQKSIQNMRNSFSNLEPDWEIKLGMAQENISLTQTNLRLANVSLSYLEQQAE---KEQQVFEVWNNSMAQQLQQLRDQIAKARHAAEAIDVSLESLGPKCIRSYLPASYGLSTSNKIRMSFALSNHLESSPLIHLASSEGR-HITLELYKRRVRLVWNLGGTTATVTHPMVVHTRDPKYDDAWYHVEANRTLNLGSLVVRRMNNYGELTPPNPVIITGSTDTEHTRFYQSRSDRISLGGFASKDLQFTPG----LNVVVHQVEVDNKPLGLWNFVTSEGSCGGSMVGAKESSASSTARHFNGLGYAQLMKTRPRPTRKNLFSVQMTFRTLDENALLFLAVDDKNNRSVSVTLSRGRIMFRIDYGDESKLEINTTKKYNVGQWIKIEAAREFSAKRSTENGMLRVNNDRPISGAPTLPVNIHLLPDLSKTVYYLGGVPPGFTSGTSKAPGADN-PFLGCMKDVQVNGETYDPLESSSYYGVEP-SCKNMITKAGFSGNGYLELPSQSLRKRSNTALVFRTLQPDCLLLLAAYPPEILG-DYDAKDIKGNFSISLVDGQLHVWVNSGR---SFIKMSSNSSQMNDGEFHVVHLIKTGRKLELMVDDELQEIRNLNGNPTVVSLPRDAGGLYIGGAPPHESYTPLAPTFVNLEGAIRDVVFNNRTINFNDALTFANVQIGRNGPLMGSLKGG---LYDVLLKTEPMIGKSFTASP-----EGCKRIGSYSYEPNAFKFGDDIYSYSQLKLPERHFWQRNFHLSFDFRSFYPNGMLYLSPGSKEKPKHYVALVLKDGQLVLVVRGRRREELQLTAKLNDGEWHRVTISCHDRKVTMSVEIGRTDQKTSAQMKLPKKIGASQLLLVGGLPQSPVKVSSDLYVRLEPFKGCLRRVSINNNTQDLARPGKHSNVGQCFPTVERGSYFPGDAYAIYKKNFNVGKYLDLETEFRTSELSGILLSVSDPNGFPALSLELHNGNIIFSCDPGNGAPMRVESSLPTKYALCDNKWHNISALYDGEQIVLRIDQLPAVISVGNQGNAGKVQTRSPLYIGGLPESAPSGSLISRENFKGCIRHVSIRNERRDWIEMEDLRNVLLSECLVSSDES-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :* . . :: *:. *: * *:*.::*:...* *:.*****::*.* *** * * . .. .:*.* :. .. .. :: *****:::.* ::.**** ***:*.*** * :*:******..****:***. :::****..::*::* :*: :.* : :* *:**:: :** ***** :* **::.**.* * ****::* ::****:*:* ::: : : .* : :: :**:.::.*.. * ***. . .* :* *:***** .*::*** *:::*:: * *** *:*:*:**.* ** ::. *:* .*::*****:** * **:* :.. . ** ** *:* * . .. *** * ** * .*:.*. ** * **: *:*. ** . ..* * * ** **** **.* *:*:*. :* :** .*:*****: *:*: :: : .* :**: :: * :: . .. **.*. ** *:*.: *.:* :.:*:*: . : . : :*: *:: * *. . : . : :* . .* . * *.:*: :*..*. **:: :: . . :* ...* . :: ** * **.**:* *** * .:*: : . * ** * .*:::*: :*:* .* .:* * *:.* *:**:* :*:.:**: *****. ******:*:*. ** ** **** :*: * :****:* **.*** * * : : * .* *** .*.** ** *. * *. * ***** : .: *: *:*. **:*. *. :**** * .** *::**:*:. :.* ..** *.*:..**:..:*: :*** *: ** *::*:.*:.*:*.*. ** *... *: *:*:.*:**** * * *.:* *.*** . **: *:*. :**: **. . ***.*: :** ** * *::.** * *.* * . :: . ..*..***.** * *::** * ..***.*:** **: *:*** : :*.::. :*. . : : :*: . :. :* *: ..::. . .*:*::** ** *.: :*** * ::: *. .:. . * : . :: : : .*. *.: : *. ***: : ::* *: :: * :*::*:*:* .:: :.:: *: * : : *. :*:*.** :.****: .*** : : . :* ..**:*:*:** ** **.:****: :*.**.*.:** *:** . *:.** *.** . .**: .* . : .* ** *: **** .** *.* *. :** *:*.* * . ** ** * ** *.** *** *: : : : *:** ***. : : : ::*** :****: * *. :: : .:* :* :. : * *. :: :. . : * :: . :. * : .* *.: * . : .* *: :: :* :: .* : :: . . .:. ::. : * ..* : :::: * : .. . .:*: : :: : .:: :: :::*.: *. * *::.: * . ::. .:* *. .:. ::: :: . : :**.**::* * :: ::* : * * *:***.: *::*. .: **: . * : . * : * ** .*::* :: :** * :. : .:.* : ::* . . *: .:*..:.: .: : : : * .:.: : * : .::::.::.:::.:.:* . . .:.:: . .: : *..:: ***:*: .: : :: ::.: :::.:::: * :**: *::*.**:.* * .*:*:* * * . .: . :.. : .. *::*.*:: .:::*: * :* ::*::*. .. * :* :. *. **:: *.** . *:: ** :: * :. * . : . :* : . . : :**::.* : . :. : :. .****:***** .**.* *. *..: ..:..* :. * . : :** *: :* :.***:...***: . . . :** *: *:: . * * .. .: :.:::* *:* : : ::.:: .:: ::.:: . *.: . * . * :. *:**:*. . * .: : **:**:::. .*: *.*..* ** .. : : ...*. *::**.. .: :: * * * : . ::**.: . : :. ::* * *:*.* :.:* * : .:.. ::**. * **: :* : : :*:: : ::**. : * :. *::*****. . :** .: ::*.: ::*:*. .::* .::* *.:*** . . :: ::.:*: :*. .. * .. : .: :** . *: : : : :. :* : :.::.*: .*:*: . : :... .. : :. . * :.:::***:**::.* .:: : *: . . :. : .: . :* :* ***** . .: : .:.**:*.: : : . ** :* . :** **...: *:** * .:* .*:** * :* ****: :*:**.:*. : : .:.:*: : :::* * * * : . . :*:.:**:::* .:: * :* . . * ..: ..:*..*:::**:* . . .* : *:**** :.: : . :*:: : : * * : ", "identical_positions": 815, "similar_positions": 1071, "identity": "23.51%" }, { "cls_id": "homologset.agr.RGD:1308891", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q6IE26-1", "uniprot_id": "EPHX4_MOUSE", "id": "Q6IE26-1", "name": "Epoxide hydrolase 4", "aln": "MAPPR------PPRLLPALRALLYWSLVYGYCGLCASVHLLKLLWSIGRAPAQTFRRAARANPPACLNDPSLGTHCYVRIK----------------------------------------------------------DSGLRFHYVAAGERGKPLMLLLHGFPEFWYSWRHQLREFKSEYRVVALDLRGYGESDAPAHQESYKLDCLIADIKDILDSLGYSKCVLIGHDWGGMIAWLIAVCYPEMIMKLIVIN-FPHPSVFTEYILRHPAQLFRSSFYYFFQIPRFPEFMFSINDFKALKHLFTSQSTGIGRKGRQLTTEDLEAYVYVFSQPGALSGPINHYRNIFSCLPLKHHMVTT--PTLLLWGEEDAFMEVEMAEVTKIYVKNYFRLTILSEGSHWLQQDQPDIVNGLIWAFLKEETRRD-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZKP8-1", "uniprot_id": "D3ZKP8_RAT", "id": "D3ZKP8-1", "name": "", "aln": "MAPPR------PPRLLPALRALLYWSLVYGYCGLCASVHLLKLLWSIGRAPAQTFRRAARANPPACLNDPSLGTHCYVRIKVKAVAGLETGEGEGRGWEPREPRCLGLRADYSSPDSCGHPEDPRGGRRDWAGGLFRARDSGLRFHYVAAGERGKPLMLLLHGFPEFWYSWRHQLREFKSEYRVVALDLRGYGESDAPIHQESYKLDCLIADIKDVLDSLGYNKCVLIGHDWGGMIAWLIAVCYPEMIMKLIVIN-FPHPSVFTEYILRHPAQLFRSSFYYFFQIPRLPELMFSINDFKALKHLFTSQSTGIGRKGRQLTTEDLEAYVYVFSQPGALSGPINHYRNIFSCLPLKHHMVTT--PTLLLWGEEDAFMEVEMAEVTKIYVKNYFRLTILSEGSHWLQQDQPDIVNGLIWAFLREETRRD-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8IUS5-1", "uniprot_id": "EPHX4_HUMAN", "id": "Q8IUS5-1", "name": "Epoxide hydrolase 4", "aln": "MARLRD----CLPRLMLTLRSLLFWSLVYCYCGLCASIHLLKLLWSLGKGPAQTFRRPAREHPPACLSDPSLGTHCYVRIK----------------------------------------------------------DSGLRFHYVAAGERGKPLMLLLHGFPEFWYSWRYQLREFKSEYRVVALDLRGYGETDAPIHRQNYKLDCLITDIKDILDSLGYSKCVLIGHDWGGMIAWLIAICYPEMVMKLIVIN-FPHPNVFTEYILRHPAQLLKSSYYYFFQIPWFPEFMFSINDFKVLKHLFTSHSTGIGRKGCQLTTEDLEAYIYVFSQPGALSGPINHYRNIFSCLPLKHHMVTT--PTLLLWGENDAFMEVEMAEVTKIYVKNYFRLTILSEASHWLQQDQPDIVNKLIWTFLKEETRKKD----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4ILH2-1", "uniprot_id": "A0A0R4ILH2_DANRE", "id": "A0A0R4ILH2-1", "name": "", "aln": "MARLLHNLLLLTVGLTLKIRVMGYWSLIYGYCALCTGVALIKLGWNIILRPSTTFQWTVREIPPSCLNDTSLGTHCYVRIK----------------------------------------------------------ESGLRFHYVAAGERGKPLMLFLHGFPEFWFSWRHQLREFKSEFRVVAVDMRGYGESDLPSSTESYRLDYLVTDIKDIVEYLGYNRCFLVGHDWGGIIAWLCAIHYPEMVTKLIVLN-SPHPCVFTDYALRHPSQMLKSSYYFFFQLPYFPELMLSINDFKALKSLFTSRSTGISCKGRWLTTEDLEAYLYALSQPGALTGALNYFRNVFSVLPLSHSEVKS--PVLLLWGERDAFLEQDMAEACRLYIRNLFRLNIISGASHWLQQDQPDIVNKLIWTFIKEGEGRKNYRNL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P53750-1", "uniprot_id": "YN93_YEAST", "id": "P53750-1", "name": "Uncharacterized hydrolase YNR064C", "aln": "-----------------------------------------------------------MSNIIARFHKIQVQ-------------------------------------------------------------------DGVKVWYREAGAAGNPTILLLHGFPTSSNMFRNLIPLLAGQFHIIAPDLPGFGFTETPENYK-FSFDSLCESIGYLLDTLSIEKFAMYIFDYGSPVGFRLALKFPSRITGIVTQNGNAYEEGLDDRFWGPLKEYWKS---YQSDPVFVKSLIPYLEDPANVICQYHDGVPAIESVDPAAYTLDIALIQRTGQTDIQLRLFFDYQNNIKLYPAFQKFLRDSKIPVLVAWGANDTIFSVAGAEAYRKDVDN-LKVVYYDTGHFALETHVVAIAEEIISMFAEN----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . .: .*::. * ** *:* :*:***** :* : : .:::::* *: *:* :: * : : :* * .* ::: *. .: : .*:*. :.: *: :*. : ::. * .: : : : :* : : . .:: ::* : : . ..* . * *: . . * ::: .*: .:.: : *.*: ** .*:::. **. : : * ::: . . . *: . *.: :* * .: ", "identical_positions": 46, "similar_positions": 105, "identity": "10.67%" }, { "cls_id": "homologset.agr.RGD:1308892", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q4KLK7-1", "uniprot_id": "Q4KLK7_RAT", "id": "Q4KLK7-1", "name": "Nucleolar protein 56", "aln": "-MVLLHVLFEHAVGYALLALK-EVEEISLLLPQVEECVLNLGKFHNVVRLVAFCPFSSSQVALENANAVSEGVVHEDLRLLLETYLP---SKKKKVLLGVGDPKIGAAIQEELGYN-CQTGGVIAEILRGVRLHFHNLVKGLTDLSACKAQLGLGHSYSRAKVKFNVNRVDNMIIQSISLLDQLDKDINTFSMRVREWYGYHFPELVKIINDNATYCRLAQFIGNRRELNEEKLEKLEEIT-MDGAKAKAILDASRSSMGMDISAIDLINIESFSSRVVSLSEYRQSLHNYLRSKMSQVAPSLSALIGEAVGARLIAHAGSLTNLAKYPASTVQILGAEKALFRALKTRGNTPKYGLIFHSTFIGRAAAKNKGRISRYLANKCSIASRIDCFSEVPTSVFGEKLREQVEERLSFYETGEIPRKNLDVMKEAVVQAEEAAAEITRKLEKQEKKRLKKEKKRLAALALASSENSS-TPEECEEVNEKPKKKK-LKPQETLQENGMEDPPVSLPKTKKKKAFPKEELAS-DLEEMATSSISVPKKKKSLPKEEVASEPEEAASPITPKKKRKFSEEPEAAAS----CTKSSTKKKKKSQKAREED", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D6Z1-1", "uniprot_id": "NOP56_MOUSE", "id": "Q9D6Z1-1", "name": "Nucleolar protein 56", "aln": "-MVLLHVLFEHAVGYALLALK-EVEEISLLLPQVEECVLNLGKFHNVVRLVAFCPFSSSQVALENANAVSEGVVHEDLRLLLETYLP---SKKKKVLLGVGDPKIGAAIQEELGYN-CQTGGVIAEILRGVRLHFHNLVKGLTDLSACKAQLGLGHSYSRAKVKFNVNRVDNMIIQSISLLDQLDKDINTFSMRVREWYGYHFPELVKIVNDNATYCRLAQFIGNRRELNEEKLEKLEEIT-MDGAKAKAILDASRSSMGMDISAIDLINIESFSSRVVSLSEYRQSLHTYLRSKMSQVAPSLSALIGEAVGARLIAHAGSLTNLAKYPASTVQILGAEKALFRALKTRGNTPKYGLIFHSTFIGRAAAKNKGRISRYLANKCSIASRIDCFSEVPTSVFGEKLREQVEERLSFYETGEIPRKNLDVMKEAVVQAEEAAAEITRKLEKQEKKRLKKEKKRLAALALASSENSS-TPEECEEVNEKSKKKKKLKPQ----ENGMEDPPVSLPKSKKKKA-PKEELAS-DLEEMATSSA---KRKKSSPKEEVASEPEEAASPTTPKKKRKFSEEPEVAAN----FTKSSTKKKKKSQKAQED-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00567-1", "uniprot_id": "NOP56_HUMAN", "id": "O00567-1", "name": "Nucleolar protein 56", "aln": "-MVLLHVLFEHAVGYALLALK-EVEEISLLQPQVEESVLNLGKFHSIVRLVAFCPFASSQVALENANAVSEGVVHEDLRLLLETHLP---SKKKKVLLGVGDPKIGAAIQEELGYN-CQTGGVIAEILRGVRLHFHNLVKGLTDLSACKAQLGLGHSYSRAKVKFNVNRVDNMIIQSISLLDQLDKDINTFSMRVREWYGYHFPELVKIINDNATYCRLAQFIGNRRELNEDKLEKLEELT-MDGAKAKAILDASRSSMGMDISAIDLINIESFSSRVVSLSEYRQSLHTYLRSKMSQVAPSLSALIGEAVGARLIAHAGSLTNLAKYPASTVQILGAEKALFRALKTRGNTPKYGLIFHSTFIGRAAAKNKGRISRYLANKCSIASRIDCFSEVPTSVFGEKLREQVEERLSFYETGEIPRKNLDVMKEAMVQAEEAAAEITRKLEKQEKKRLKKEKKRLAALALASSENSSSTPEECEEMSEKPKKKKKQKPQEVPQENGMEDPSISFSKPKKKKSFSKEELMSSDLEETAGSTS-IPKRKKSTPKEETVNDPEEAGHRSGSKKKRKFSKEEPVSSGPEEAVGKSSSKKKKKFHKASQED", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q12460-1", "uniprot_id": "NOP56_YEAST", "id": "Q12460-1", "name": "Nucleolar protein 56", "aln": "MAPIEYLLFEEPTGYAVFKVKLQQDDIGSRLKEVQEQINDFGAFTKLIELVSFAPFKGAAEALENANDISEGLVSESLKAILDLNLPKASSKKKNITLAISDKNLGPSIKEEFPYVDCISNELAQDLIRGVRLHGEKLFKGLQSGDLERAQLGLGHAYSRAKVKFSVQKNDNHIIQAIALLDQLDKDINTFAMRVKEWYGWHFPELAKLVPDNYTFAKLVLFIKDKASLNDDSLHDLAALLNEDSGIAQRVIDNARISMGQDISETDMENVCVFAQRVASLADYRRQLYDYLCEKMHTVAPNLSELIGEVIGARLISHAGSLTNLSKQAASTVQILGAEKALFRALKTKGNTPKYGLIYHSGFISKASAKNKGRISRYLANKCSMASRIDNYSEEPSNVFGSVLKKQVEQRLEFYNTGKPTLKN--------------------ELAIQEAMELYNKDK---------------PAAEVEETKEKESSKK----------RKLEDDDEEKKEKKEKKS----------------------KKEKKEKKE---------------KKDKKEKKD----------------KKEKKDKKKKSKD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ::***...***:: :* : ::*. :*:* : ::* * .::.**:*.** .: ****** :***:* *.*: :*: ** ****:: *.:.* ::*.:*:**: * * :. : :::****** .:*.*** . . :*******:********.*:: ** ***:*:************:***:****:*****.*:: ** *:.:*. ** :: .**::.*..* : *.. *: ::* :* *** *** *: *: *:.**.**::**:.*: ** .** ***.** ****.:*****:********:* .*******************:*********:** **.:*:****************:***** :** *:.***. *::***:**.**:**: . ** :* ** .* ::.* .. * ** .** ..** . :** . : *:**: *::*. ** **.:* .:: **:** :* .. ", "identical_positions": 259, "similar_positions": 148, "identity": "43.02%" }, { "cls_id": "homologset.agr.RGD:1308893", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K0V2-1", "uniprot_id": "DCNL3_MOUSE", "id": "Q8K0V2-1", "name": "DCN1-like protein 3", "aln": "MGQCV------------TKCKNPSSTLGSKNGDRDPSNKSHSRRGASHREEQVPPCGKPAGDILVNGTKKAEAATEACQLPTS--------SGDAGRES---KTNAEES---SLQRLEELFRRYKD-EREDAILEEGMERFCNDLCVDPTEFRVLLLAWKFQAATMCK-FTRKEFFDGCKAISADSIDGICARFPSLLTEAKQE-DKFKDLYRFTFQFGLDSEEGQRSLHREIAIALWKLVFTQNN-----PPVLDQWLNFLTENPSGIKGISRDTWNMFLNFT---QVIGPDLSNYSEDEAWPSLFDTFVEWEMER-------RKREVEGRGTLSSGQEGLCPEEQT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4V8B2-1", "uniprot_id": "DCNL3_RAT", "id": "Q4V8B2-1", "name": "DCN1-like protein 3", "aln": "MGQCV------------TKCKNPSSTLGSKNGDRDPSSKSHSRRGASHREEQVPPCGKPAGDILVNGTKKAEAATEACQLPTS--------SGDAGRES---KTNAEES---SLQRLEELFRRYKD-EREDAILEEGMERFCNDLCVDPTEFRVLLLAWKFQAATMCK-FTRKEFFDGCKAISADSIDGICARFPSLLTEAKQE-DKFKDLYRFTFQFGLDSEEGQRSLHREIAIALWKLVFTQNN-----PPVLDQWLNFLTENPSGIKGISRDTWNMFLNFT---QVIGPDLSNYSEDEAWPSLFDTFVEWEMER-------RKREVEGRGALSSGPEGLCPEEQT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8IWE4-1", "uniprot_id": "DCNL3_HUMAN", "id": "Q8IWE4-1", "name": "DCN1-like protein 3", "aln": "MGQCV------------TKCKNPSSTLGSKNGDREPSNKSHSRRGAGHREEQVPPCGKPGGDILVNGTKKAEAATEACQLPTS--------SGDAGRES---KSNAEES---SLQRLEELFRRYKD-EREDAILEEGMERFCNDLCVDPTEFRVLLLAWKFQAATMCK-FTRKEFFDGCKAISADSIDGICARFPSLLTEAKQE-DKFKDLYRFTFQFGLDSEEGQRSLHREIAIALWKLVFTQNN-----PPVLDQWLNFLTENPSGIKGISRDTWNMFLNFT---QVIGPDLSNYSEDEAWPSLFDTFVEWEMER-------RKREGEGRGALSSGPEGLCPEEQT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8T8S1-1", "uniprot_id": "DCNL3_DROME", "id": "Q8T8S1-1", "name": "DCN1-like protein 3", "aln": "MGNCLKCFQSAAEQSMPTNASSPNSHNSNSNACQTATSLANCYESVGINPNANERCALETDELLSSRTPLKPAKANNCDTKRNSFKSLGLLNGSAPTMSDIITTAVQESMEVSHQTLSKLFDVYKDPDDEEMILTDGIERLCNDLNYQPDEFAILVLAWCLDASQMCR-FTKVEFIEGLHKMRADTIDSIRVRLEQTIEMLKADAEMFKQLYRFTFRFGLEPD--QRVLSLEMAIDLWKLVFTVQT-----PDLFSNWIHFLEKHPN-IRRIPKDTWNMYLNFT---EQC--DIQNYDDTEAWPSLFDDFVDYEKSRALVSSGIHDDDNNNDDPLQSHVKAEDPGLVS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12395-1", "uniprot_id": "DCN1_YEAST", "id": "Q12395-1", "name": "Defective in cullin neddylation protein 1", "aln": "-------------------------MSNNKIKRKDASPEQEAIESFTSLTKCDPKVSR--KYLQRNHWNINYALNDYYDKEIG-------------TFTDEVSTVAHPP--VYPKELTQVFEHYIN---NNLFDIDSLVKFIEELGYNLEDLATLCLAHLLGYKKLEEPLKREDFLSTWFMQGCSTISDMQECIKTLDVKLHEDLQYFTQIYNYAFNLILDPN--RKDIDTDEGIQYWKLFFQPEYPVRMEPDLLEAWFRFLRDEGK--TTISKDTWRMLLLFFKRYPTIQKIISDYDETAAWPFIIDEFYECLQDQQ------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ... : .: .. .. : . : . * : : . : .: .. . : * ::* * : :: : :.: :: ::* : :: * ** : : . :.: :*:. ..:*..: : : : : *.::*.::*.: *:.: :: : : .* ***.* : * ::. *:.** .. . *.:***.* * * :.:*.: *** ::* * : .: ", "identical_positions": 36, "similar_positions": 98, "identity": "10.34%" }, { "cls_id": "homologset.agr.RGD:1308894", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "F7F5A1-1", "uniprot_id": "F7F5A1_RAT", "id": "F7F5A1-1", "name": "E2 ubiquitin-conjugating enzyme", "aln": "SNGQRRPGGGLRPEATRGPARPRPRLLLLLFQYELGGQGRRGQPAGPRRALCPGRARADACASAPTSPTPQPGGEEARRERARAGARGSSSRPLRQAGGEHARSAAAAAAPAPPPLARSLARSPARPPARNLLTARPGGAEPSRAGRREAERAGGSRVPAPRPAERPPHRGSRSAGRRHPPAAARHCTAACDFRCSTLPGRSLGGGFFSRPPGPPPRLPPFPQGRFLGALPPPQRSGARAGRAGGREVFPRDNFTKMSSDRQRSDDESPSTSSGSSDADQRDPAAPEPEEQEERK-PS-----------ATQQKKNTKLSSKTTAKLSTSAKRIQKELAEITLDPPPNCSAGPKGDNIYEWRSTILGPPGSVYEGGVFFLDITFSSDYPFKPPKVTFRTRIYHCNINSQGVICLDILKDNWSPALTISKVLLSICSLLTDCNPADPLVGSIATQYLTNRAEHDRIARQWTKRYAT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P52483-1", "uniprot_id": "UB2E3_MOUSE", "id": "P52483-1", "name": "Ubiquitin-conjugating enzyme E2 E3", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSDRQRSDDESPSTSSGSSDADQRDPAAPEPEEQEERK-PS-----------ATQQKKNTKLSSKTTAKLSTSAKRIQKELAEITLDPPPNCSAGPKGDNIYEWRSTILGPPGSVYEGGVFFLDITFSSDYPFKPPKVTFRTRIYHCNINSQGVICLDILKDNWSPALTISKVLLSICSLLTDCNPADPLVGSIATQYLTNRAEHDRIARQWTKRYAT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q969T4-1", "uniprot_id": "UB2E3_HUMAN", "id": "Q969T4-1", "name": "Ubiquitin-conjugating enzyme E2 E3", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSDRQRSDDESPSTSSGSSDADQRDPAAPEPEEQEERK-PS-----------ATQQKKNTKLSSKTTAKLSTSAKRIQKELAEITLDPPPNCSAGPKGDNIYEWRSTILGPPGSVYEGGVFFLDITFSSDYPFKPPKVTFRTRIYHCNINSQGVICLDILKDNWSPALTISKVLLSICSLLTDCNPADPLVGSIATQYLTNRAEHDRIARQWTKRYAT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0S6A7-1", "uniprot_id": "B0S6A7_DANRE", "id": "B0S6A7-1", "name": "E2 ubiquitin-conjugating enzyme", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSERQRSDDESPSTSSGSSDADQRDLPVPEPEEQEERKQPTP----------PQQQKKSTKLSSKTTAKLSSSAKRIQKELAEITLDPPPNCSAGPKGDNIYEWRSTILGPPGSVYEGGVFFLDITFSSDYPFKPPKVTFRTRIYHCNINSQGVICLDILKDNWSPALTISKVLLSICSLLTDCNPADPLVGSIATQYLTNRAEHDRIARQWTKRYAT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P52485-1", "uniprot_id": "UBCD2_DROME", "id": "P52485-1", "name": "Ubiquitin-conjugating enzyme E2-24 kDa", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSTPAAG----------SAAEVATSSATSNAPSAPSTTASNVSNTSQPTTAGTPQARGGRGSNANGGASGSNAGGGDEPRKEAKTTPRISRALGTSAKRIQKELAEITLDPPPNCSAGPKGDNLYEWVSTILGPPGSVYEGGVFFLDIHFSPEYPFKPPKVTFRTRIYHCNINSQGVICLDILKDNWSPALTISKVLLSICSLLTDCNPADPLVGSIATQYLQNREEHDRIARLWTKRYAT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*. . .:***::.. . .: .. *: : * : : :*.:* :.: : *.:****************************:*** ******************** **.:********************************************************************* ** ******* *******", "identical_positions": 147, "similar_positions": 30, "identity": "30.95%" }, { "cls_id": "homologset.agr.RGD:1308895", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K618-1", "uniprot_id": "A0A0G2K618_RAT", "id": "A0A0G2K618-1", "name": "", "aln": "MLGICRGRRKFLAASLTLLCIPALTWIYLFAGSLEDGKPVSLSPLESQAHSPRYTASSQRERESLEVRVREVEEENRALRRQLSLAQ------GQSPAHRRGNHSKTYSMEEGTGDSENQRAGIVAGNSSECGQQPAVEKCETIHVAIVCAGYNASRDVVTLVKSVLFHRRNPLHFHLIADSIAEQILATLFQTWMVPAVRVDFYNADELKSEVSWIPNKHYSGIYGLMKLVLTKTLPANLERVIVLDTDITFATDIAELWAVFHKFKGQQVLGLVENQSDWYLGNLWKNHRPWPALGRGYNTGVILLLLDKLRKMKWEQMWRLTAERELMGMLSTSLADQDIFNAVIKQNPFLVYQLPCFWNVQLSDHTRSEQCYRDVSDLKVIHWNSPKKLRVKNKHVEFFRNLYLTFLEYDGNLLRRELFGCPSETDVNSENLQKQLSELDEDDLCYEFRRERFTVHRTHLYFLHYEFEPSADHTDVTLVAQLSMDRLQMLEAICKHWEGPISLALYLSDAEAQQFLRYAQGSEVLMSRQNVGYHIVYKEGQFYPVNFLRNVAMKHISTPYMFLSDIDFLPMYGLYEYLRKSVIQLDLANTKKAMIVPAFETLRYRLSFPKSKAELLSMLDMGTLFTFRYHVWTKGHAPTNFAKWRTATTPYQVEWEADFEPYVVVRRDCPEYDRRFVGFGWNKVAHIMELDAQEYEFTVLPNAYMIHMPHAPSFDITKFRSNKQYRVCLKTLKEEFQQDMSRRYGFAALKYLTAENNS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z1M7-1", "uniprot_id": "LARG1_MOUSE", "id": "Q9Z1M7-1", "name": "Xylosyl- and glucuronyltransferase LARGE1", "aln": "MLGICRGRRKFLAASLTLLCIPAITWIYLFAGSFEDGKPVSLSPLESQAHSPRYTASSQRERESLEVRVREVEEENRALRRQLSLAQ------GQSPAHHRGNHSKTYSMEEGTGDSENLRAGIVAGNSSECGQQPAVEKCETIHVAIVCAGYNASRDVVTLVKSVLFHRRNPLHFHLIADSIAEQILATLFQTWMVPAVRVDFYNADELKSEVSWIPNKHYSGIYGLMKLVLTKTLPANLERVIVLDTDITFATDIAELWAVFHKFKGQQVLGLVENQSDWYLGNLWKNHRPWPALGRGYNTGVILLLLDKLRKMKWEQMWRLTAERELMGMLSTSLADQDIFNAVIKQNPFLVYQLPCFWNVQLSDHTRSEQCYRDVSDLKVIHWNSPKKLRVKNKHVEFFRNLYLTFLEYDGNLLRRELFGCPSETDVNNENLQKQLSELDEDDLCYEFRRERFTVHRTHLYFLHYEFEPSADNTDVTLVAQLSMDRLQMLEAICKHWEGPISLALYLSDAEAQQFLRYAQGSEVLMSRQNVGYHIVYKEGQFYPVNLLRNVAMKHISTPYMFLSDIDFLPMYGLYEYLRKSVIQLDLANTKKAMIVPAFETLRYRLSFPKSKAELLSMLDMGTLFTFRYHVWTKGHAPTNFAKWRTATTPYQVEWEADFEPYVVVRRDCPEYDRRFVGFGWNKVAHIMELDAQEYEFTVLPNAYMIHMPHAPSFDITKFRSNKQYRICLKTLKEEFQQDMSRRYGFAALKYLTAENNS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95461-1", "uniprot_id": "LARG1_HUMAN", "id": "O95461-1", "name": "Xylosyl- and glucuronyltransferase LARGE1", "aln": "MLGICRGRRKFLAASLSLLCIPAITWIYLFSGSFEDGKPVSLSPLESQAHSPRYTASSQRERESLEVRMREVEEENRALRRQLSLAQ------GRAPSHRRGNHSKTYSMEEGTGDSENLRAGIVAGNSSECGQQPVVEKCETIHVAIVCAGYNASRDVVTLVKSVLFHRRNPLHFHLIADSIAEQILATLFQTWMVPAVRVDFYNADELKSEVSWIPNKHYSGIYGLMKLVLTKTLPANLERVIVLDTDITFATDIAELWAVFHKFKGQQVLGLVENQSDWYLGNLWKNHRPWPALGRGYNTGVILLLLDKLRKMKWEQMWRLTAERELMGMLSTSLADQDIFNAVIKQNPFLVYQLPCFWNVQLSDHTRSEQCYRDVSDLKVIHWNSPKKLRVKNKHVEFFRNLYLTFLEYDGNLLRRELFGCPSEADVNSENLQKQLSELDEDDLCYEFRRERFTVHRTHLYFLHYEYEPAADSTDVTLVAQLSMDRLQMLEAICKHWEGPISLALYLSDAEAQQFLRYAQGSEVLMSRHNVGYHIVYKEGQFYPVNLLRNVAMKHISTPYMFLSDIDFLPMYGLYEYLRKSVIQLDLANTKKAMIVPAFETLRYRLSFPKSKAELLSMLDMGTLFTFRYHVWTKGHAPTNFAKWRTATTPYRVEWEADFEPYVVVRRDCPEYDRRFVGFGWNKVAHIMELDVQEYEFIVLPNAYMIHMPHAPSFDITKFRSNKQYRICLKTLKEEFQQDMSRRYGFAALKYLTAENNS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q66PG2-1", "uniprot_id": "LARG1_DANRE", "id": "Q66PG2-1", "name": "Xylosyl- and glucuronyltransferase LARGE1", "aln": "MLGMCRGRRKFVAASLALIFIPALTWLYLSSANIT-VKPLPLSPLDPQSSA---VVGAAAEHQSLELRLRDVEEHNNALRREISRTPRVPTHSSHPSSSRHGNQLHTHSTEEGTGDSE-AKKGAAAGNSSDCVPQPVVKKCETIHIAIVCAGYNASRDVVTLVKSVLFHRRNPLHFHIITDSIARKILADLFHTWMVPAVHVNFYDADELKSEVSWIPNKHYSGIHGLMKLVLTKTLPSDLEKVIVLDTDITFATDIAELWVVFHKFKGQQVLGLVENQSDWYLGNLWKNHRPWPALGRGFNTGVILLLLDRLRKLKWEQMWRLTAERELMSMLSTSLADQDIFNAVIKQNPFLVHQLPCYWNVQLSDHTRSEKCYKDVSDLKVIHWNSPKKLRVKNKHVEFFRNLYLTFLEYDGNLLRRELFGCPSETDHNSENLQKTLSELDEDDPCYEFRRERFTVHRTHVYFLHYEYEPTVDNTDVTLVAQLSMDRLQMLEAICKHWEGPISLALYLSDAEAQQFLRYAQGSEVLMSRSNVGYHIVYKEGQFYPVNLLRNVAMGQVNTPYMFLSDIDFLPMYGLYEYLRKSVVQLDMGNTKKALVVPAFETLRYRLSFPKSKAELLSQLDMGTLFTFRYHVWTKGHAPTDFAKWRTATTPYRVQWEADFEPYVMVRRESPEYDRRFVGFGWNKVAHIMELDAQEYEFVVLPNAYMIHMPHAPSFDITKFRSNKQYRACLKTLKEEFQQNMSRRYGFAALKYMTVDNNS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:*******:****:*: ***:**:** :..: **:.****:.*: : ...: *::***:*:*:***.*.****::* : .:..: ::**: :*:* ******** : * .*****:* **.*:******:*******************************:*:****.:*** **:*******:*:**:*******************:************::**:******************.**************************************:**********:***:***************.***********************:****:************:**:***************************************************:* *.***** ******** ***************:******:**:.* ******************************************************* *****************:****** ::.*************************:***:.*****::********************** *********************:***********:*:*********:***:.**********************.***** **************************** ***********:************:*.:***", "identical_positions": 631, "similar_positions": 93, "identity": "82.81%" }, { "cls_id": "homologset.agr.RGD:1308896", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5NSW5-1", "uniprot_id": "DBX1_RAT", "id": "Q5NSW5-1", "name": "Homeobox protein DBX1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMFPGLLAP-------------------------PAGYPSLLRPTPTLTLPQSLQS---------AFSGHSSFLVEDLIRISRP----------PTYLPRSIPTASLSPPRQEAPTALADSGTSDLGSPGSGSRRG-----------SSPQTALSPASEPTFLKFGVNAILSSA---------------PRRETSPALLQSPPPKTFAFPYFEG--------SFQPFIRSSYFPASSSVVPIPG--TFSWPLAARGKPRRGMLRRAVFSDVQRKALEKTFQKQKYISKPDRKKLASKLGLKDSQVKIWFQNRRMKWRNSKERELLSSGGCREQTLPTKLNPHPDLSD--------------------------------------VGQKGPGDEEED----------------------------------SPGASLAYHAPPDP--------------------------------------------------------RHL----LEGPLPASPAHSSSPGKPSD---------------------FSDSDEDEEGEEDEEITVS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P52950-1", "uniprot_id": "DBX1_MOUSE", "id": "P52950-1", "name": "Homeobox protein DBX1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMFPGLLAP-------------------------PAGYPSLLRPTPTLTLPQSLQS---------AFSGHSSFLVEDLIRISRP----------PTYLSRSIPAASLSPPSQEAPAALADSGTSDLGSPGSGSRRG-----------SSPQTALSPASEPTFLKFGVNAILSSA---------------PRRETSPALLQSPPPKTFAFPYFEG--------SFQPFIRSSYFPASSSVVPIPG--TFSWPLAARGKPRRGMLRRAVFSDVQRKALEKTFQKQKYISKPDRKKLASKLGLKDSQVKIWFQNRRMKWRNSKERELLSSGGCREQTLPTKLNPHPDLSD--------------------------------------VGQKGPGDEEED----------------------------------NPGARLAYHAPADP--------------------------------------------------------RHL----LEGPLPASPAHSSSPGKPSD---------------------FSDSDEDEEGEEDEEITVS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NMT0-1", "uniprot_id": "DBX1_HUMAN", "id": "A6NMT0-1", "name": "Homeobox protein DBX1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMFPGLLAP-------------------------PAGYPSLLRPTPTLTLPQSLQS---------AFSGHSSFLVEDLIRISRP----------PAYLPRSVPTASMSPPRQGAPTALTDTGASDLGSPGPGSRRG-----------GSPPTAFSPASETTFLKFGVNAILSSG---------------PRTETSPALLQSVPPKTFAFPYFEG--------SFQPFIRSSYFPASSSVVPIPG--TFSWPLAARGKPRRGMLRRAVFSDVQRKALEKMFQKQKYISKPDRKKLAAKLGLKDSQVKIWFQNRRMKWRNSKERELLSSGGCREQTLPTKLNPHPDLSD--------------------------------------VGQKGPGNEEEEEGP------------------------------GSPSHRLAYHASSDP--------------------------------------------------------QHLRDPRLPGPLPPSPAHSSSPGKPSD---------------------FSDSEEEEEGEEQEEITVS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9PTU1-1", "uniprot_id": "DBX1A_DANRE", "id": "Q9PTU1-1", "name": "Homeobox protein DBX1-A", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMIPSVIAP-------------------------PAIYSAFMRP------AASLHS---------PFPAHPSFLVEDLLRINRP----------SGFLSQTAHSPCASPPNSTPLSIPDNCRILDRVSPGITEKHGP----------CSPKTPVS-SKDPTYLKFGVSAILAPS---------------PKKATSPPSVHSIHPKGFSVPYFDG--------SFCPFVRSSYFPAPSSVVPIPG--TFSWPLAARGKPRRGMLRRAVFSDVQRKALEKMFQKQKYISKPDRKKLAAKLGLKDSQVKIWFQNRRMKWRNSKERELLSSGGCREQTLPTKTNPHPDLSD--------------------------------------VGKKSSEDEDED------------------------------------DACAPSHFCLSP--------------------------------------------------------RRV---------MSNSTDSSITFKHSD---------------------FSESED--------EITVS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9PTU0-1", "uniprot_id": "DBX1B_DANRE", "id": "Q9PTU0-1", "name": "Homeobox protein DBX1-B", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMLPSVIAP-------------------------PAMYPSFLRPSSALSLPPALQS---------AFTTHSSFLVEDLLRISRP----------AAFMHRSIPSPSASPPATGVTTLNTTSSAVHVAMSTALAKRS-----------SSPQTSIS--SDPNYLKFGVNAILAST---------------TRNASPPPPVQGMNAKTFPFPCFDG--------SFHPFIRASYFPASSSAVPIPG--TFAWPLTARGKPRRGMLRRAVFSDVQRKALEKMFQKQKYISKPDRKKLATKLGLKDSQVKIWFQNRRMKWRNSKERELLSSGGCREQTLPTKMNPNPDLSD--------------------------------------VGKRFEHEAVLR-----------------------------------ESPRAPFCQSRGD--------------------------------------------------------HEFN-------ADLHFKSPSISSKHSD---------------------FSESED-------EEITVS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W064-1", "uniprot_id": "Q9W064_DROME", "id": "Q9W064-1", "name": "", "aln": "MSTAFLVDSLLHAQQTYTESQLKSSLSEMLLSRRSATGTDAADPADQPTESCGCSKLRGYKCDKCREIRAESVESIEEMDEDDGSSSADEIVADIGSVEGEEPHMDLDEELEEELADVDEPVSIKLPKVEPKETSMPTVGNTILKDTNSKPILKFSVSAILGDTREGVRVRNEFMQPQHIWPYLQQNFMQQHSHQYQQHHQQQQPHSHPQHQPLAVPGHQHSHPHSHHHHHHHPGAGHAHFPHPAFLTHQLPPHQHHQQQQHVQQQHPGNSCQPQTASSSSSPGSTISDSDNNHGASTANGNGSGTGNSGQDARPHELANSNPDEDSSASRRLTQDKQQQQQLLGAGGTGGGGGGGHGHGHPTPPPPPPPPVIAKPMPSRPTPFLPHTLNHPHLHSLLAHCRNPYMSVGAQVFPLPPGQGFPWAHSTRGKPRRGMMRRAVFSDSQRKGLEKRFQQQKYISKPDRKKLAERLGLKDSQVKIWFQNRRMKWRNSKERELLASGGSRDQTLPNKNNPNPDLSDAKCDRPLTPLSPSLLSPNGSATPPPPGAVAKDEPPTAAVTPKSPQSVSSRSSPSVGYGLQISSPPPLLTSLKMGDQSASATPTPLPGTTVSSAAASPPGVTASEFQAKINAEMQKQLVAADLKFKLENSIQEAKQRRFEQLQQQLHHSPHFSAMREVELAAAAAAAQLHHHHQQQQQQQQQQHAQQQHAQQQHQGGSEFMKLYYDDYDDSNSDSDEEISVT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* * : * . : .: * . : : .. *.:**..:* .: . :. :.. *.* .. .* * . * . :*.. . ..*. : . . * : *: .. * .*:.. :...*:* *.*. ::********:******* ***.*** **:************* :****************************:***.*:****.* **:***** * : . . . :.. . : .: : :. : **:*:", "identical_positions": 107, "similar_positions": 83, "identity": "14.44%" }, { "cls_id": "homologset.agr.RGD:1308898", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0U1RS37-1", "uniprot_id": "A0A0U1RS37_RAT", "id": "A0A0U1RS37-1", "name": "", "aln": "------MQTERSSQG-FGNRYRQIPFMYDVKRSVYNEENFQQEHRRKGPTSGNMDINITTFKHHVQCRCSWHKFLRCMLTVFPFLEWMCLYRFKDWLLGDLLAGLSVGLVQVPQGLTLSLLTRQLIPPLNVAYAAFCSSVIYVIFGSCHQMSIGPFFLVSALMINVLKERPFNNGH-----------------------LIMGTFVKDDFS----------VPTFYLNYNRSLSMVASTTFLTGIIQLSMGMLGMGFVATYLPEAATSAYLAAVALHIILAQMTCIFGIMVSFHAGPIAFIYNIINYCIALPKANSTSILLFLTAVVALRVNKCIRIS--FNRYPIEFPMELLLILGFSMLTSRITMATENSKMLINMIPYSFVFPETPEFGILSRIVLQALSLSVVSSFLLISLGKKIANLHNYRTNSNQDLIAIGLCNLVSSFFRCCVFTGGMARTIIQDKSGGRQQKKLACFSANRRPQLQTGTNACLTRSLQPALSPQFASLVGAGVMLLLMVKIGSFFDNLPNAVLAGIILSNVVPYLETIYNLPTLWRQDQYECVVWMVTFSAAIFLGLDVGLLISLVFTFFVITVRSHRTKILVLGQIPNTN-IYRNVNEYREVILIPGVKILQCCSSITFVNVYHLKHKLLKEVNMVKLPLKEEEIYALFHESETSIAENKLCRCFCDCEELEPESRVVYTERYENKQE-HGSSINLIRCSYLGSGDSSQTTSEEQVPYT-VSSTSQRNIGQNYEDTEKAWLPNSPPRNSSLPPPENSESLAQSRSRSVILPYSDT------HTIILDFSMVHYVDNRALVVLRQMCNAFHNADILVLISGCHTSVVKLFEKNDFFDDGITKAQLFLSLHDAVLFALSRKCSEPSDLSVDETETVIQETYSESDKNDNLSNLRFKPGNVIMEGSQHASPNYTKTHRPAKNDLEFDLDPDRLLASDQTSGMDLNLDLDLDLGRESDLDPGSELGSEIQAKP--ELESELEIDVQTEPETEEESERERKSQP--------------RTRTRAQSPWQSYLTAYRFGSTSSQSAGPPQT-PQTRPAEKR----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R0C3-1", "uniprot_id": "S26A8_MOUSE", "id": "Q8R0C3-1", "name": "Testis anion transporter 1", "aln": "------MQTERSLQS-FSNRYTQIPFVYDVKRSVYNEENFQQEHRKKGPTSGNVDIDITTFKHHVQCGCSWHKFLRCMLTVFPFLEWICLYRFKDWLLGDLLAGLSVGLVQVPQGLILSLLTRQLIPPLNVTYAAFCSSVIYVIFGSCHQMSIGPFFLVSALMINVLKDRPFNNGH-----------------------LILGTFVKDDFS----------VPTFYLSYNRSLSMVASTTFLTGIIQLSMGMLGMGFMATYLPEAATSAYLAAVALHIILAQMTCILGIMVSFHAGPISFIYNIINYCIALPKANSTSILLFITSVVALRINKCIRIT--FNRYPIEFPMELLLILGFSLLTSKITMATENSKMLMNMIPYSFVFPENPEFGILSRVVLQALSLSFVSSFLLISLGKKIANFHNYRTNSNQDLIAIGLCNLLSSFFKCCVFTGSLSRTTIQDKSGGRQQ---------------------------------FASLVGAGVMLLLMVKMESFFHNLPNAVLAGIILSNVVPYLEAIYNLPSLWRQDQYECIIWMVTFSSAILLGLDVGLLISLAFTFFVITIRSHRTKILVLGQIPNTN-IYRNVNDYREVILIPGVKIFQCCSSITFVNVYHLKQKVLKEVNMVKLPLKEEEIYTLFHESETSIAENKLCRCFCDCEELEPEIRVVYTERYENRQE-QDSSINLIRCSYLGSGDSSQVTSEEQIPYT-VSSTSQRNIVQSYEDTEKAWLPNSPPRNSPLPPPEASESLAQSRSRSIIMPYSDTSVQNNTHTIILDFSMVHYVDNRALVILRQMCNAFYNANILVLISGCHTSVVKSFEKNDFFDEGITKAQLFLSLHDAVLFALSRKFSEPSDLSMDETETVIQETYSESDKNGNLSNLRLKTGKAIIEGSQHASPGFTKNLKPGKDDLEFDLELDPMLSFEQSSGMDLNLDLDLDLD-QSELDPGSELDSEIQAKPELELESELETDAQTEPETEEEPELEPEPEPEPETEPEPEPERERKTRTRSQSPWRNYFTAYRFGSSNSQSRAPPQTRPEKRKPHNYPNSP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96RN1-1", "uniprot_id": "S26A8_HUMAN", "id": "Q96RN1-1", "name": "Testis anion transporter 1", "aln": "-----MAQLERSAISGFSSKSRRNSFAYDVKREVYNEETFQQEHKRKASSSGNMNINITTFRHHVQCRCSWHRFLRCVLTIFPFLEWMCMYRLKDWLLGDLLAGISVGLVQVPQGLTLSLLARQLIPPLNIAYAAFCSSVIYVIFGSCHQMSIGSFFLVSALLINVLKVSPFNNGQ-----------------------LVMGSFVKNEFS----------APSYLMGYNKSLSVVATTTFLTGIIQLIMGVLGLGFIATYLPESAMSAYLAAVALHIMLSQLTFIFGIMISFHAGPISFFYDIINYCVALPKANSTSILVFLTVVVALRINKCIRIS--FNQYPIEFPMELFLIIGFTVIANKISMATETSQTLIDMIPYSFLLPVTPDFSLLPKIILQAFSLSLVSSFLLIFLGKKIASLHNYSVNSNQDLIAIGLCNVVSSFFRSCVFTGAIARTIIQDKSGGRQQ---------------------------------FASLVGAGVMLLLMVKMGHFFYTLPNAVLAGIILSNVIPYLETISNLPSLWRQDQYDCALWMMTFSSSIFLGLDIGLIISVVSAFFITTVRSHRAKILLLGQIPNTN-IYRSINDYREIITIPGVKIFQCCSSITFVNVYYLKHKLLKEVDMVKVPLKEEEIFSLFNSSDTNLQGGKICRCFCNCDDLEPLPRILYTERFENKLDPEASSINLIHCSHFESMNTSQTASEDQVPYT-VSSVSQKNQGQQYEEVEEVWLPNNSSRNSSPGLPDVAE----SQGRRSLIPYSDASLLPSVHTIILDFSMVHYVDSRGLVVLRQICNAFQNANILILIAGCHSSIVRAFERNDFFDAGITKTQLFLSVHDAVLFALSRKVIGSSELSIDESETVIRETYSETDKND---NSRYKMSSSFLGSQKNVSPGFIKIQQPVEEESELDLELE----SEQEAGLGLDLDLDRELEPEMEPKAETETKTQTEMEPQPETEPEMEPNPKSRPRAHTFPQQRYWPMYHP-----------SMASTQSQTQTRTWSVERRRHPMDSYS-------PEGNSNEDV----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VVM6-1", "uniprot_id": "Q9VVM6_DROME", "id": "Q9VVM6-1", "name": "", "aln": "MPSDKESPETKPLNNNNTNGNGGSVPSKPKIQPKYSIHRDVLTHEVVIKQTGYAARDKSIPSSLRNCWRSWN-FFALFTGVIPILQWLPQYSPRRDLPGDIIAGFTVAIMNIPHGMAYGILAG--VSAGNGLYMAVFPVLAYMFLGTSKHISIGTFAVASMMTAKVVDTYANVDDHHQILPINAFGLQSNGTATASPLLLINSSALADSVSSTTISPFQLLNSTLNADPITKIEVATSLALTVGIVNLLMAFLRLGTLSSLLSEPLVNGFTTAAACHVVTAQLKDVLGISVPRHKGAFKIIYTVIDVIKGVPQTNLVNFGFCMAVIAFMMICNEILKPRLSKKCRFPLPAELIMVIGGTLISKWFNLYVDYNVNPVGKIPSGLPEPVLPRLDLVPKVAVDSIAIAIVTYSIIMSMGLTFAKKHGYEVRPNQELFAMGIGNMVGGCFSCIPMACSLSRSVIQDQTGGVSQ---------------------------------IASLVSASLVVVTLMWIGPFFSSLPRCVLAGVIIVALKPMFMQAKELKKFSKQGKLEMFTWISTFLCVVIIDIDIGLLIGICISLLALYIKGLKPYSCLLGYMPEAPGIYMDLNQHRNAMQVPEVRIFRYSGSLNFATSLFFRRALYEAVGLDKIPLTK-----------------------------------------------------------VSSSNSNSPSKGSKSSYSPVSQNGGKAINGKLEETSGAFK-----------------------------------------VLVLDFSMLGHIDVAGCRTLTDLSKELKVRGARLLLASPVDRVYDTLVHSMALSEGP--FEIFPTLHDCVEYANACRTA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . . : *. . *. :* : : :* **: *: . ::*:*:*: * : * **::**::*.::::*:*: .:*: :.. * * *. . : *:::*:.:::***.* :.* : :*:. . :.: *: .: : :..* .: . .:.:.:: :: .**::* *..* :* ::: *.*. ..: :*.* *:: :*:. ::** :. * *.: ::* :*: .:*::* ..: . :: :. : : : * . :: : :* **::::* ::::. :.: .: . :. ** .: * * :.::.:: :::::::.*: ::: :* .:*. *.* ...**:*:*:*: *::.. * . :: .::*: ***::** .* :****.*.:::: :: : ** .**..****:*: : * : :* .: :*.: : *: ** . :::.:*:**:*.: ::: ::. :. :** :*:: ** .:*::*: : :* *:*:: ..*:.*.. .::: : : *.: *:**.: . * ::.. :. .: .*: **. . : . *:.. .: .::*****: ::* . * ::.: : . :*::. : : :. :. * ::* ::**.* :* : : ", "identical_positions": 140, "similar_positions": 319, "identity": "12.99%" }, { "cls_id": "homologset.agr.RGD:1308899", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZA74-1", "uniprot_id": "D3ZA74_RAT", "id": "D3ZA74-1", "name": "", "aln": "-------MARLRALLHCLLPWYCALCAAAGSQTPDPRLSGKLHDYVVTVPCSTDFQGRFLSH---------------VVSAPAAASS--------------RSHLRVARSPLSLERETPRP---RHHFLYFNVTVFGKLLHLRLQPNR------RLVAPGAPVEWQEDFRELFRQPLQRECVYTG---------GVTGMPGAAVAISNCDGLAGLIRTDNSDFFIEPLER-----------GQQEKEAGGRTHVVYRR-----------EAVQREWTEPHGDLHNEAFGLGDLPNVLDLVGDQ------------LGDTERKRRHAKPGSYSIEVLLAVDDSVVRFHGREHTQN-------YVLTLMNIVDEIYHDESLGAHVNIALVRLIMVGYRQSLSLIERGNPARSLEQVCRWAHSQQRQDPSHTEHHDHVIFLT-------RQNFGPSGMQGYAPVTGMCHPLRSCALNHEDGFSSAFVVAHETGHVLGMEHDGQGNGCDDETSLGSVMAPLVQAAFHRFHWSRCSKLELSRYLPS--YNCLLD-DPFERTWPQPP--ELPGIDYSMDEQCRFDFGTGYHTCLAFRTFEPCKQLWCSHPDNPYFCKTKKGPPLDGTECAPGKWCFKGHCVWKSPEQTYGQDGGWSSWTNFGSCSRSCGGGVRSRSRSCDNPPPAYGGRLCSGPMFEYQICNSEDCPGPFEDFRAQQCAKRNSYYTHQDAKHSWLPYEPDSEAQKCELICQSADTGDVVFMNQVVHDGTRCSYRDPYSVCARGECVPFGCDKEVGSMKTDDKCGVCGGDNSHCRTVKGTLGKASKQAAALKQVQIPAGARHIQIELLEKAPRRIAVKNQVTGSFILNPKGKEASSRTFTALGLEWEHAAEDTKDSLKTNGPLPEAIAVLVLPPAEGKPRGSLAYKYVIHEDLLPLIGSNNVLLEEMDSYEWALKSWSPCSKACGGGIQFTKYGCRHRRDHHMVQRHLCDHKKRPKAIRRRCNQHPCPQPTWVTEEWGACSRSCGKLGLQTRGVQCLLPLSNGTHKAMPAKACLGNRPEAKRPCLRVPCPAQWRTGAWSQCSATCGKGIQQRQVVCRNSSSALGPCEGVKPDTVRICSQPACGGDLQNSTVNAEVQDPVTKMGPWEPQSRPLTPMNRISTMEPCVGDRSVFCRMEVLDRYCTIPGYLRLCCESCIKKASSSN----ASLASLPTFSTPGSLLPEPTATQEDMESTRGPTRLEDHRQSQPTQLSGAVDRISSVTQHLVTPQMLSPKASESNSPATPQGPPWGRTQTAVPTSEGQGQSREEPGHSGTSLPTTSPVT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9PX39-1", "uniprot_id": "E9PX39_MOUSE", "id": "E9PX39-1", "name": "", "aln": "-------MAWLRALLHCLLPWYCALCAAAGSQTPDLRLSGKLHDYVVTVPCSTDFQGRFLSH---------------VVSAPAAPSP--------------RSHLRVARSPLSLERETPRPGGPRQHFLYFNVTVFGKLLHLRLQPNR------RLVAPGAPVEWQEDFRELFRQPLQQECVYTG---------GVTGMPGAAVAISNCDGLAGLIRTDNSDYFIEPLER-----------GQQEKEAGGRTHVVYRR-----------EAVQREWKEPHGDLHNEAFGLGDLPNVLDLVGDR------------LGDAERKRRHAKPGSYSIEVLLAVDDSVVRFHGREHTQN-------YVLTLMNIVDEIYHDESLGAHVNIALVRLIMVGYRQSLSLIERGNPARSLEQVCRWAHSQQRQDPSHTEHHDHVIFLT-------RQNFGPSGMQGYAPVTGMCHPLRSCALNHEDGFSSAFVVAHETGHVLGMEHDGQGNGCDDETSLGSVMAPLVQAAFHRFHWSRCSKLELSRYLPS--YDCLLD-DPFERTWPQPP--ELPGIDYSMDEQCRFDFGTGYHTCLAFRTFEPCKQLWCSHPDNPYFCKTKKGPPLDGTECAPGKWCFKGHCIWKSPEQTYGQDGGWSSWTNFGSCSRSCGGGVRSRSRSCDNPPPAYGGRPCSGSMFEYQICNSEDCPGPYEDFRAQQCAKRNSYYTHQDAKHSWLPYEPDSDAQKCELICQSADTGDVVFMNQVVHDGTRCSYRDPYSVCARGECVPFGCDKEVGSMKTDDKCGVCGGDNSHCRTVKGTLGKGSKQAAALKQVQIPAGARHIQIELLEKAPHRIAVKNQVTGSFIFNPKGKEASSRTFTALGLEWEHEAEDTKDSLRTNGPLPEAIAILVLPPAEGKPRGSLAYKYVIHEDLLPLIGSNNVLLEETDTYEWALKSWSPCSKACGGGIQFTKYGCRRRRDHHMVHRHLCDHKKRPKPIRRRCNQHSCPQPTWVTEEWGACSRSCGKLGLQTRGVQCLLPLSNGTHKAMPAKACLGNRPEAKKPCLRVPCPAQWRTGAWSQCSATCGEGIQQRQVVCRNTSSALGPCEGVKPDMVQICSLPACGGDLQNSTVKAEVQDPVTKTGYREPQSRPLTPEDRISTMEPCVRDRSVFCRMEVLDRYCTIPGYHRLCCESCIKKTSGPN----ASLALPPTFSTPGSLLPAPKATLEDVKSTRGPTSLEDHRQSQPTQLPDVADRISPVTQYPVTPQMLSPKAFPGNSPATPRRPPQDWTQTAMPTSEGQGQSREEPGHGGTSLPATSPVT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WXS8-1", "uniprot_id": "ATS14_HUMAN", "id": "Q8WXS8-1", "name": "A disintegrin and metalloproteinase with thrombospondin motifs 14", "aln": "-------MAPLRALLSYLLPLHCALCAAAGSRTPELHLSGKLSDYGVTVPCSTDFRGRFLSH---------------VVSGPAAASAGSMVVDTPPTLPRHSSHLRVARSPLHPG-GTLWPGRVGRHSLYFNVTVFGKELHLRLRPNR------RLVVPGSSVEWQEDFRELFRQPLRQECVYTG---------GVTGMPGAAVAISNCDGLAGLIRTDSTDFFIEPLER-----------GQQEKEASGRTHVVYRR-----------EAVQQEWAEPDGDLHNEAFGLGDLPNLLGLVGDQ------------LGDTERKRRHAKPGSYSIEVLLVVDDSVVRFHGKEHVQN-------YVLTLMNIVDEIYHDESLGVHINIALVRLIMVGYRQSLSLIERGNPSRSLEQVCRWAHSQQRQDPSHAEHHDHVVFLT-------RQDFGPS---GYAPVTGMCHPLRSCALNHEDGFSSAFVIAHETGHVLGMEHDGQGNGCADETSLGSVMAPLVQAAFHRFHWSRCSKLELSRYLPS--YDCLLD-DPFDPAWPQPP--ELPGINYSMDEQCRFDFGSGYQTCLAFRTFEPCKQLWCSHPDNPYFCKTKKGPPLDGTECAPGKWCFKGHCIWKSPEQTYGQDGGWSSWTKFGSCSRSCGGGVRSRSRSCNNPSPAYGGRLCLGPMFEYQVCNSEECPGTYEDFRAQQCAKRNSYYVHQNAKHSWVPYEPDDDAQKCELICQSADTGDVVFMNQVVHDGTRCSYRDPYSVCARGECVPVGCDKEVGSMKADDKCGVCGGDNSHCRTVKGTLGKASKQAGALKLVQIPAGARHIQIEALEKSPHRIVVKNQVTGSFILNPKGKEATSRTFTAMGLEWEDAVEDAKESLKTSGPLPEAIAILALPPTEGGPRSSLAYKYVIHEDLLPLIGSNNVLLEEMDTYEWALKSWAPCSKACGGGIQFTKYGCRRRRDHHMVQRHLCDHKKRPKPIRRRCNQHPCSQPVWVTEEWGACSRSCGKLGVQTRGIQCLLPLSNGTHKVMPAKACAGDRPEARRPCLRVPCPAQWRLGAWSQCSATCGEGIQQRQVVCRTNANSLGHCEGDRPDTVQVCSLPACGGNHQNSTVRADVWELGTPEGQWVPQSEPLHPINKISSTEPCTGDRSVFCQMEVLDRYCSIPGYHRLCCVSCIKKASGPNPGPDPGPTSLPPFSTPGSPLPGPQDPADAAEPPGKPTGSEDHQHGRATQLPGALDTSSPGTQHPFAPETPIPGASWSISPTTPGGLPWGWTQTPTPVPEDKGQPGEDLRHPGTSLPAASPVT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W1Z6-1", "uniprot_id": "Q9W1Z6_DROME", "id": "Q9W1Z6-1", "name": "", "aln": "MTVAAIGSNRHRRLALIVLTTLWLLIGASSSSSSTSSTNPKSVNIELRRKRSLHYNGIELDKNTLVGHLREHERALIFGSRSPEEAPEFKLVHLAQQRPEEQQRLEERKRPGEAEQHGGNPHQRRQRRSLPSEDGNGPLPPEEEEQEAGEDVEARLQLQQSPQLIDDAFIFIRRTENGTQFVEHSPQLLKRLERCFYRSPAAALDLCEPGNVRGVFQQNGSDLVIHPLPARFGTGTHVLYQARVDKSGGGYSEASSRRTASPLDSQLQFEPDAEEFNEPRRRLRAQSQLQSPLRLRFQPRHHHPHQHHQQRRRRYIGDAPRSRWSDIPEELFIETAIFVDSDLYAHMQKNFPTNTESKVVSFLLAMINGVQLLYHHPTLGRRINFVLKRLEIWKSWDPPGLVRSRDVENYLNSFCKWQEKLNPFSDADPLHYDHALVLTGLDLVTYDKGKANSQVVGMATVKGMCTSIYSCTINEAKHFESVFVVAHEIGHNLGMRHDAKEISCDPTMHI---MSPKLGSG--KVTWSKCSRTYLEDFLMDPQAECLFDRDSFAGPWDHTAGGRLPGERFNANQQCMLRFGKNFMQASTQSKMEICRDLHCRQDGLPWTS----HPALEGTECGPNMWCRGGTCEARSSKQ--GSYSALKSWPPEHIPEATHEKIIRHEPNRIP-------------PLLHDYNPMDNELPG---------------------SPSNWGEWS---EPSACESGCLYGQSRRLLEGSTGLRTLNRSCLNFPSRCIGR-----------------DRRFVTCNTPQCHKVPVQTINDFATQVCMQARKSDPELTGEGQQLPSTLDASCKIFCRTRTN--------GTKSRRWTFPDG------------TTCKAKQHNPEDITYCISGRCER----------------------------------------FSCDNSTSNFFKMDSSFCEAR--SVRPTRDSSDQESRQQTNRQRYAERQEGKPQKNHYENEVAKRPSYGQGNHINAPASPYKRRNYHKPYPPEIPRPPPPASASLIALDRSSSSESEWVAHPGCHSNCMTDSKGVQGVTSRLTGVES--IQLCSYRIQPCERLQTAAEYAEQTCARYRQKVRGLSGHGAQISASIDEPDRSCRVG-CQDEFIKYRYYLVNGRNGHFPPGTRCSPVGKRYCVYG----------RCLEFGDDDLPLDKTHISLGQLRTRRKRSSISNDLFNITEIFIKPSHSDISAENIEFTQPIHVSADELSSKSR-----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * :*. * .*:.* :. . * : : * .:.* *.: . * .. :. .:*. : * * :: . * . . : ** :. :: * : * : * . . *.**: :.: ..: *::: :.:* .*.** .: :*...* :.. ** *. .*: ** *: :: . * : .: :**: *.* * . **. : **..: . ::. * ::*:::* *: :**. :** ::*:.* ** : :. .*:. : . *:..*:* .. : . :.. *:**.:.** :. . * * *.*.*** .: **::*. . *.*.**:*** ** ***.**.: .* : *:* : :. :. **:**: *. :* . :**:* *.* .* :.. .*** :. ::** : **..: . : .:* *::* * : . *: . *.*:****.*. ** * * :*.:* *. .. .**. . : :* ... .::. .:: ** : .* :. :.. ** * .:: :: . :: .*.. . * .* * : .*. :.* .*: . .:: . : : .. *: .:. :* :.:.. *.:: **. : ::. ** *: * .*.:: .. ::: . *. * *. .*::.* :. *:* :: :* * ...*.. * : .. . * : * . ..* .* ...:: . * . * :.* . : * * :. . . :: *. ..: :.* . * * .: :: . * : : * .* :* * . . . . *. . * . . .. : .:. . . : . . : .: . . .. ", "identical_positions": 190, "similar_positions": 353, "identity": "14.43%" }, { "cls_id": "homologset.agr.RGD:1308901", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D8N6-1", "uniprot_id": "LIN37_MOUSE", "id": "Q9D8N6-1", "name": "Protein lin-37 homolog", "aln": "MFPVKVKVEKSEMEMAKARNQLDAVLQCLLEKSHMDRERLDEEAGKTPLDTHNKDCSIAATGKRPSARFPHQRRKKRREMDDGLAEGGPQRSNTYVIKLFDRSVDLAQFSENTPLYPICRAWMRNSPTVRERERSPGSPLPPLPEDGEGSEVINSKNRDVYKLPPPTAPGPLGDACRSRIPSPLQPETEGTPDDEPSEPEPSPSTLIYRNMQRWKRIRQRWKEASHRNQLRYSESMKILREMYDRQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A503-1", "uniprot_id": "D4A503_RAT", "id": "D4A503-1", "name": "", "aln": "MFPVKVKVEKSEMEMAKARNQLDAVLQCLLEKSHMDRERLDEEAGKTLSDTHNKDCSIAATGKRPSARFPHQRRKKRREMDDGLAEGGPQRSNTYVIKLFDRSVDLAQFSENTPLYPICRAWMRNSPTVRERERSPGSPLPPLPEDGEGSEVINSKNRDVYKLPPPTAPAALGDACRSRIPSPLQPETQGTTDDEPSEPEPSPSTLIYRNMQRWKRIRQRWKEASHRNQLRYSESMKILREMYDRQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96GY3-1", "uniprot_id": "LIN37_HUMAN", "id": "Q96GY3-1", "name": "Protein lin-37 homolog", "aln": "MFPVKVKVEKSELEMAKARNQLDAVLQCLLEKSHMDRERLDEEAGKTPSDTHNKDCSIAATGKRPSARFPHQRRKKRREMDDGLAEGGPQRSNTYVIKLFDRSVDLAQFSENTPLYPICRAWMRNSPSVRERECSPSSPLPPLPEDEEGSEVTNSKSRDVYKLPPPTPPGPPGDACRSRIPSPLQPEMQGTPDDEPSEPEPSPSTLIYRNMQRWKRIRQRWKEASHRNQLRYSESMKILREMYERQ", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "************:********************************** ******************************************************************************:***** **.********* ***** ***.**********.*.. *************** :**.***************************************************:**", "identical_positions": 229, "similar_positions": 10, "identity": "93.09%" }, { "cls_id": "homologset.agr.RGD:1308903", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q3LRZ1-1", "uniprot_id": "CRTC2_RAT", "id": "Q3LRZ1-1", "name": "CREB-regulated transcription coactivator 2", "aln": "MATSGANGPGSATASASNPRKFSEKIALQKQRQAEETAAFEEVMMDIGSTR----LQAQKLRLAYTRSSHYGGSLPNVN----QIGCGLAEFQSPLHSPLDSSRSTRHHGLVERVQRDPRRMVSPLRR-YPRHIDSSPYS--------------PAYLSPP-PESGWRRMMP--------------------WGNLPAEKGQLFRLPSALNRTSSDSALHTSVMNPNPQDTYPGPTPPSVLPSRRGG-----------FLDGEMDAKVPAIEENLVDDKHLLKPWDAKKLSSSSSRPRSCEVPGIN-----------------------IFPSPDQPANVPVLPPAMSTG----------------------GSLPDLTNLHFPPPLPTPLDPEETVYPSLSGGNSTTNLTHTMTHLGISGGLG-LGPS--------------YDVPGLHSPLSHPSLQSSLSNPNLQASLSSPQPQLQGSHSHPSLPASSLAHHALPTTSLGHPSLSAPALSSSSSSSSTSSPVLSAPPYPASTPG---------------ASPRHRRVPLSPLSLPAGPADARRSQQQLPKQFSPTMSPTLSSITQG---------------------------VPLDTSKLPTDQRLPPYPYSPPSLVIPSHPPTPKSLQQ--LPSQACLVQPSGGQPPGRQPHYGTLYPPGSS---GHGQQPYHRPINDFSLGN------------LEQFNMESPSTSLVLDPPAFSEGPGFLGSEGSVSGPQDSHVLNHQNLTHCSRHGSGPNIILTGDSSPGFSKEIAAALAGVPG--FEVSASGLELGLGLEDELRMEP----------------------LGLEGLTMLSDP-------CALLPDPAVEDSFRSDRLQ--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3U182-1", "uniprot_id": "CRTC2_MOUSE", "id": "Q3U182-1", "name": "CREB-regulated transcription coactivator 2", "aln": "MATSGANGPGSATASASNPRKFSEKIALQKQRQAEETAAFEEVMMDIGSTR----LQAQKLRLAYTRSSHYGGSLPNVN----QIGCGLAEFQSPLHSPLDSSRSTRHHGLVERVQRDARRMVSPLRR-YPRHIDSSPYS--------------PAYLSPP-PESGWRRMMP--------------------WGNLPAEKGQLFRLPSALNRTSSDSALHTSVMNPNPQDTYPGPTPPSVLPSRRGGG----------FLDGEMDAKVPAIEENVVDDKHLLKPWDAKKLSSSSSRPRSCEVPGIN-----------------------IFPSPDQPANVPVLPPAMNTG----------------------GSLPDLTNLHFPPPLPTPLDPEETVYPSLSGGNSTTNLTHTMTHLGISGGLG-LGPS--------------YDVPGLHSPLSHPSLQSSLSNPNLQASLSSPQPQLQGSHSHPSLPASSLAHHALPTTSLGHPSLSAPALSSSSSSSSTSSPVLSAPPYPASTPG---------------ASPRHRRVPLSPLSLPAGPADARRSQQQLPKQFSPTMSPTLSSITQG---------------------------VPLDTSKLPTDQRLPPYPYSPPSLVIPTHPPTPKSLQQ--LPSQACLVQPSGGQPPGRQPHYGALYPPGSS---GHGQQPYHRPINDFSLGN------------LEQFNMESPSTSLVLDPPAFSEGPGFLGSEGSMSGPQDPHVLNHQNLTHCSRHGSGPNIILTGDSSPGFSKEIAAALAGVPG--FEVSASGLELGLGLEDELRMEP----------------------LGLEGLTMLSDP-------CALLPDPAVEDSFRSDRLQ--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q53ET0-1", "uniprot_id": "CRTC2_HUMAN", "id": "Q53ET0-1", "name": "CREB-regulated transcription coactivator 2", "aln": "MATSGANGPGSATASASNPRKFSEKIALQKQRQAEETAAFEEVMMDIGSTR----LQAQKLRLAYTRSSHYGGSLPNVN----QIGSGLAEFQSPLHSPLDSSRSTRHHGLVERVQRDPRRMVSPLRR-YTRHIDSSPYS--------------PAYLSPP-PESSWRRTMA--------------------WGNFPAEKGQLFRLPSALNRTSSDSALHTSVMNPSPQDTYPGPTPPSILPSRRGG-----------ILDGEMDPKVPAIEENLLDDKHLLKPWDAKKLSSSSSRPRSCEVPGIN-----------------------IFPSPDQPANVPVLPPAMNTG----------------------GSLPDLTNLHFPPPLPTPLDPEETAYPSLSGGNSTSNLTHTMTHLGISRGMG-LGPG--------------YDAPGLHSPLSHPSLQSSLSNPNLQASLSSPQPQLQGSHSHPSLPASSLARHVLPTTSLGHPSLSAPALSSSSSSSSTSSPVLGAPSYPASTPG---------------ASPHHRRVPLSPLSLLAGPADARRSQQQLPKQFSPTMSPTLSSITQG---------------------------VPLDTSKLSTDQRLPPYPYSSPSLVLPTQPHTPKSLQQPGLPSQSCSVQSSGGQPPGRQSHYGTPYPPGPS---GHGQQSYHRPMSDFNLGN------------LEQFSMESPSASLVLDPPGFSEGPGFLGGEGPMGGPQDPHTFNHQNLTHCSRHGSGPNIILTGDSSPGFSKEIAAALAGVPG--FEVSAAGLELGLGLEDELRMEP----------------------LGLEGLNMLSDP-------CALLPDPAVEESFRSDRLQ--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M9PFU2-1", "uniprot_id": "M9PFU2_DROME", "id": "M9PFU2-1", "name": "", "aln": "---------------MANPRKFSEKIALQKQKQAEGTAEFERIMKEVYATKRDEPPANQKILDGLVGGQEVSQSSPGAGNGTGGGGSGSGSGASGGGASPDGLGGGGGSPTAYRESRGRSVGVGPMRRPSERKQDRSPYGSSSTQQTLDNGQLNPHLLGPPTAESLWRRSSSDSALHQSALVAGFNSDVNSMGANYQQQQHQQQQQPGQPRSHSPHHGINRTMSPQAQRRKSPLLQPHQLQLQQLQQQQQQMQHQHQLHQQLQMQQLQQHQQQHQQQQQQQNTPYNNAKFTNPVFRPLQDQVNFANTGSLPDLTALQNYGPQQQQQQSQQQPSQQQQQLQQTLSPVMSPHNHRRERDQSPSPFSPAGGGGGAGPGSPYQQQQHSPTGNTQQQQQQHQQPSNSPHLSFTNLATTQAAVTTFNPLPTLGPHNATDYRQPPNPPSPRSSPGLLSSVSATDLHSSAPASPIRQQQQAHQQQQQQQQAQQQQQQFDNSYNSLNTSFHNQFEIFSLGDSNSSPEQQGFANNFVALDFDDLSGGGGGGPSGGGGSNGGGLTNGYNKPEMLDFSELSGSPEASGNNNHMRRGVSNLNNNGLSNGVVGSTHNGSTNLNGAGNNNSSSGGGTAQDPLGITTSPVPSPLGCPSSPLPIPIPMSAQSSPQQQHHHHQQQQQQHHQQQHHQQQQLSLSLHHSPHHSPMHSPHHGNSPLSSSSPVSHNACSNSNVVMNHQQQQQQHHHQQHHHQGSSQSHTPTTANIPSIIFSDYSSNADYTREIFDSLDLDLGQMDVAGLQMLSDQNPIMIADPNIEDSFRRDLNXYYEEAVAAIESGVLLEEDYQALLGSEALADEQVVTVEAAGAAAAVVTVEEAATVSEKDKKDLEVVELLVSGVMDDLVDSSDLDEEVRNFFF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :**************:*** ** **.:* :: :*: **: . . ... . * *... *.* .. * :. *. . . * .*. *.*:** *: * ***. * *.** .** *** . .* :: * : *. . *.. .:: :: : . * * .: .: : :*: ::: :::: .*:: *::.. ** . :* * ** :* .*.*.*.. *. . : :..*. * : :: ** * * :**: * : : : *** . *** *.:* ..*:** . . :: . .: * * * .::: . . : : * *: .: .: : . *.**.... : : * : : * : :.: : :* :*..:* .:::: : .* . **. . * : : ** :.: *. * . * : . . : :: .* * * . . *:.. :.* * *:. . *:.. .* .:.. . . * ..* :: *.:: .: . .. . :: :* . . :* ::: :. . :* :: . :* :.:.:* *: **:: : : :* :*: ** . .::: . *. *: ", "identical_positions": 139, "similar_positions": 236, "identity": "15.38%" }, { "cls_id": "homologset.agr.RGD:1308904", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R184-1", "uniprot_id": "F110A_MOUSE", "id": "Q8R184-1", "name": "Protein FAM110A", "aln": "MPVDTLSPGAPATPALPFRLRTKVPGYLLPRPADGGARKPSAVERLEADKAKYVKSLRVANTRQEPVQPPLVRQPLFSPGPRGPVLTPSRRVLPCSGRRPQLDLDILSSLINLCDSPVSPSEASRTPGRPEGSAHKVPPATPPRPPPSTVAVRRVDVRPLPASPARPYPSPGTTTTSSPGRPPGLQRSKSDLSERFSRAAADLERFFNFCGLDPEEARGLGVAHLARASSDIVSLAGPSAGPCSSEGGCSRRSSATVEERSLDRVPYGVSVIERNARVIKWLYGLRQARDPPTTEG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G4XVC3-1", "uniprot_id": "G4XVC3_RAT", "id": "G4XVC3-1", "name": "", "aln": "MPVDTLSPGAPTTPALPFRLRTKVPGYLLPRPADGGARKPSAVERLEADKAKYVKSLRVANTRQEPVQPPLARQPLFSPGSRGPVLTPSRRVLPCSGRRPQLDLDILSSLINLCDSPVSPSEANRTPGRPEGSAHKVPPATPPRPPPSTVAVRRVDVRPLPASPARPYPSPGAATTSSPGRPPGLQRSKSDLSERFSRAAADLERFFNFCGLDPEEARGLGVAHLARASSDIVSLAGPSAGPCSSEGGCSRRSSATVEERTLERVPYGVSVIERNARVIKWLYGLRQARDPPTTEG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BQ89-1", "uniprot_id": "F110A_HUMAN", "id": "Q9BQ89-1", "name": "Protein FAM110A", "aln": "MPVHTLSPGAPSAPALPCRLRTRVPGYLLRGPADGGARKPSAVERLEADKAKYVKSLHVANTRQEPVQPLLSKQPLFSPETRRTVLTPSRRALPGPCRRPQLDLDILSSLIDLCDSPVSPAEASRTPGRAEG-AGRPPPATPPRPPPSTSAVRRVDVRPLPASPARPCPSPGPAAASSPARPPGLQRSKSDLSERFSRAAADLERFFNFCGLDPEEARGLGVAHLARASSDIVSLAGPSAGPGSSEGGCSRRSSVTVEERARERVPYGVSVVERNARVIKWLYGLRQARESPAAEG", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***.*******::**** ****:****** **************************:*********** * :****** .* .*******.** . **************:********:**.*****.** * : ************ ***************** ****.:::***.************************************************************** ***********.*****: :********:*****************:.*::**", "identical_positions": 252, "similar_positions": 28, "identity": "85.14%" }, { "cls_id": "homologset.agr.RGD:1308905", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5EB77-1", "uniprot_id": "RAB18_RAT", "id": "Q5EB77-1", "name": "Ras-related protein Rab-18", "aln": "MDEDVLTTLKILIIGESGVGKSSLLLRFTDDTFDPELAATIGVDFKVKTISVDGNKAKLAIWDTAGQERFRTLTPSYYRGAQGVILVYDVTRRDTFVKLDNWLNELETYCTRNDIVNMLVGNKIDKENREVDRNEGLKFARKHSMLFIEASAKTCDGVQCAFEELVEKIIQTPGLWESENQNKGVKLSPREESHGGGACGGYCSVL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P35293-1", "uniprot_id": "RAB18_MOUSE", "id": "P35293-1", "name": "Ras-related protein Rab-18", "aln": "MDEDVLTTLKILIIGESGVGKSSLLLRFTDDTFDPELAATIGVDFKVKTISVDGNKAKLAIWDTAGQERFRTLTPSYYRGAQGVILVYDVTRRDTFVKLDNWLNELETYCTRNDIVNMLVGNKIDKENREVDRNEGLKFARKHSMLFIEASAKTCDGVQCAFEELVEKIIQTPGLWESENQNKGVKLSHREESRGGGACGGYCSVL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NP72-1", "uniprot_id": "RAB18_HUMAN", "id": "Q9NP72-1", "name": "Ras-related protein Rab-18", "aln": "MDEDVLTTLKILIIGESGVGKSSLLLRFTDDTFDPELAATIGVDFKVKTISVDGNKAKLAIWDTAGQERFRTLTPSYYRGAQGVILVYDVTRRDTFVKLDNWLNELETYCTRNDIVNMLVGNKIDKENREVDRNEGLKFARKHSMLFIEASAKTCDGVQCAFEELVEKIIQTPGLWESENQNKGVKLSHREEGQGGGACGGYCSVL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DHC1-1", "uniprot_id": "RB18B_DANRE", "id": "Q6DHC1-1", "name": "Ras-related protein Rab-18-B", "aln": "MDDDVLTTLKILIIGESGVGKSSLLLRFTDDTFDPELAATIGVDFKVKTIAIDGNRAKLAIWDTAGQERFRTLTPSYYRGAQGVILVYDVTKRDTFTKLENWLNELETYCTRNDLVKMLVGNKIDKDNREVDRNEGLKFARKHSMLFIEASAKTRDGVQCAFEELVEKILQTPGLWESSIQNHGVQLSD-NEPQRQGACGGYCSLV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W4A0-1", "uniprot_id": "Q9W4A0_DROME", "id": "Q9W4A0-1", "name": "", "aln": "MAD---RAIKLLVIGESGVGKSSLIRRFVENKFDQNHDVTIGMDFKSKVMQVDGIDYKVALWDTAGAERFRSLTPSFYRKALGAILVYDITSRDSLVKLETWLAELDSYSDNPNIAIIVVGNKIDEE-RVVDREEGRKFARKHRALFIETSAKCDQFVSDVFKDVVEKIVSS-EYFNNGNASAGLDIAS-DRDLEASASTCYC---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : ::*:*:***********: **.::.** : .***:*** *.: :** *:*:***** ****:****:** * *.*****:* **::.**:.** **::*. . ::. ::******:: * ***:** ****** ****:*** : *. .*:::****:.: ::. . *:.:: :. .*. ** ", "identical_positions": 96, "similar_positions": 61, "identity": "46.6%" }, { "cls_id": "homologset.agr.RGD:1308906", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M1NG53-1", "uniprot_id": "A0A8M1NG53_DANRE", "id": "A0A8M1NG53-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGSPFSLKNTITSGIVSSAQRGSKELGLSNSNMDYIQTDATIDFGNSGGPLINLDGEVIGINTMKVTAGISFAIPSGRVRLFLDRSADKQK--SWFGESGSKRRYIGVMMLTLTPSIIKELRMRDLSFP-DVSHGVLIHRVIVGSPANRAGMKPGDVIIEINGVKVNTSEEIYNAVRTSE-SLNVVVRRGADLLMLHMTPESTE---------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9PLU9-1", "uniprot_id": "A0A8M9PLU9_DANRE", "id": "A0A8M9PLU9-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGSPFSLKNTITSGIVSSAQRDSKELGLSNSNKDYIQTDATIDFGNSGGPLINLDGEVIGINTMKVTAGISFAIPSDRVSLFLDRSADKQK--SWFGESGSKRRYIEVMMLTLTPSIIDELRMRDPSFP-DVSHGVLIHRVIVGSPANRAGMKPGEVIIEINGVKVNTSEEIYNAVRTSE-SLNVVVRRGADLLMLHMTPESTERHQVKYLVRLRNGEL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9PTZ3-1", "uniprot_id": "A0A8M9PTZ3_DANRE", "id": "A0A8M9PTZ3-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGSPFSLKNTITSGIVSSAQRGSKELGLSNSNMDYIQTDATIDFGNSGGPLINLDGEVIGINTMKVTAGISFAIPSDRVRLFLDRSADKQK--SWFGESGSKRRYIGVMMLTLTPSIIEELRMRDPSFA-DVSHGVLIHRVIVGSPANRAGMNPGDVIIEINGVKVNTSEEIYNAVRTSE-SLNVVVRRGADLLMLHMTPESTE---------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9QK16-1", "uniprot_id": "A0A8M9QK16_DANRE", "id": "A0A8M9QK16-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGSPFSLKNTITSGIISSAQRGSKELGLSNSNMDYIHTDATIDFGNSGGPLINLDGEVIGINTMKMTAGISFAIPSDRVRLFLDRSADKQE--SWFGESGWKRRYIGVMMLTLTPSIIEELRMRDPSFP-DVSHGVLIHRVIVGSPANRAGMKPGDVIIEINGVKVNTSEEIYNAVRTX----NVVVRRGADLLMLHMTPESTE---------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B0BNB9-1", "uniprot_id": "B0BNB9_RAT", "id": "B0BNB9-1", "name": "Serine protease HTRA2, mitochondrial", "aln": "MAALKAGRGANWSLRAWRALGGIFWRKGPLLAPDLRALLTSGTPDPQARMTYGTPSLPARVPLGVLASRANLTSGTPDLWVRLTVGTPGSSDQEDCGSPGSRRREWLAVALGAGGAVLLLLWGWGRGPSTVLAAVPAPPPTSPRSQYNFIADVVEKTAPAVVYIEILDR---HPFSGREVPISNGSGFIVASDGLIVTNAHVVADR--RRVRVRLPSGDTYEAMVTAVDPVADIATLRIQTKEPLPTLPLGRSADVRQGEFVVAMGSPFALQNTITSGIVSSAQRPARDLGLPQTNVEYIQTDAAIDFGNSGGPLVNLDGEVIGVNTMKVTAGISFAIPSDRLREFLHR-GEKKN--SWFGISGSQRRYIGVMMLTLTPSILAELQLREPSFP-DVQHGVLIHKVILGSPAHRAGLRPADVILAIGEKMIQNAEDVYEAVRTQS-QLAVRIRRGPETLTLYVTPEVTE---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JIY5-1", "uniprot_id": "HTRA2_MOUSE", "id": "Q9JIY5-1", "name": "Serine protease HTRA2, mitochondrial", "aln": "MAALKAGRGANWSLRAWRALGGIFWRKPPLLAPDLRALLTSGTPDSQIWMTYGTPSLPAQVPEGFLASRADLTSRTPDLWARLNVGTSGSSDQEARRSPGSRRREWLAVAVGAGGAVVLLLWGWGRGLSTVLAAVPAPPPTSPRSQYNFIADVVEKTAPAVVYIEILDR---HPFSGREVPISNGSGFVVASDGLIVTNAHVVADR--RRVRVRLPSGDTYEAMVTAVDPVADIATLRIQTKEPLPTLPLGRSADVRQGEFVVAMGSPFALQNTITSGIVSSAQRPARDLGLPQNNVEYIQTDAAIDFGNSGGPLVNLDGEVIGVNTMKVTAGISFAIPSDRLREFLHR-GEKKN--SWFGTSGSQRRYIGVMMLTLTPSILIELQLREPSFP-DVQHGVLIHKVILGSPAHRAGLRPGDVILAIGEKLAQNAEDVYEAVRTQS-QLAVRIRRGSETLTLYVTPEVTE---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43464-1", "uniprot_id": "HTRA2_HUMAN", "id": "O43464-1", "name": "Serine protease HTRA2, mitochondrial", "aln": "MAAPRAGRGAGWSLRAWRALGGIRWGRRPRLTPDLRALLTSGTSDPRARVTYGTPSLWARLSVGVTEPRACLTSGTPGPRAQLTAVTPDTRTREASENSGTRSRAWLAVALGAGGAVLLLLWGGGRGPPAVLAAVPSPPPASPRSQYNFIADVVEKTAPAVVYIEILDR---HPFLGREVPISNGSGFVVAADGLIVTNAHVVADR--RRVRVRLLSGDTYEAVVTAVDPVADIATLRIQTKEPLPTLPLGRSADVRQGEFVVAMGSPFALQNTITSGIVSSAQRPARDLGLPQTNVEYIQTDAAIDFGNSGGPLVNLDGEVIGVNTMKVTAGISFAIPSDRLREFLHR-GEKKN--SSSGISGSQRRYIGVMMLTLSPSILAELQLREPSFP-DVQHGVLIHKVILGSPAHRAGLRPGDVILAIGEQMVQNAEDVYEAVRTQS-QLAVQIRRGRETLTLYVTPEVTE---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VFJ3-1", "uniprot_id": "HTRA2_DROME", "id": "Q9VFJ3-1", "name": "Serine protease HTRA2, mitochondrial", "aln": "-----------------------------------MALRGSHRLEVIFKRCIASPVLHSHAAN-RRSSQLAIKEGDPNS----NGNSGQYQQNGEQKEKGWRRLVRFFVPFSLGAVVSAAIIQREDLTPTIAAS----KMTGRRRDFNFIADVVAGCADSVVYIEIKDTRHFDYFSGQPITASNGSGFIIEQNGLILTNAHVVINKPHTMVQVRLSDGRTFPATIEDVDQTSDLATLRIQVNN-LSVMRLGKSSTLRSGEWVVALGSPLALSNTVTAGVISSTQRASQELGLRNRDINYLQTDAAITFGNSGGPLVNLDGEAIGVNSMKVTAGISFAIPIDYVKVFLERAAEKRKKGSAYKTGYPVKRYMGITMLTLTPDILFELKSRSQNMPSNLTHGVLVWKVIVGSPAHSGGLQPGDIVTHINKKEIKNSSDVYDALADNSKTLDIVILRGVKQMHVTITPEDP----------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :***::*.**:*:*::**:** :::*** : : :*::***:* ********:*****.**:*:**:********* . : **.* .:*:: * . :**: : ****:*.*: **: *. .:. :: ****: :**:****: .*:.*.::: *. :.:.::*:*: : : ** . : : :*** . ", "identical_positions": 83, "similar_positions": 71, "identity": "17.18%" }, { "cls_id": "homologset.agr.RGD:1308907", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZWN4-1", "uniprot_id": "A0A8I5ZWN4_RAT", "id": "A0A8I5ZWN4-1", "name": "", "aln": "MDELVHDLASALEQTSEQSKLGELWEEMALSPRQQRRQLRKRRGRKRRSDFTHLAEHACCFSEASESSLDEATKDCREVAPLTNFSDSDDTVVAKRHPALSAIVRGKQHSWHESDSFTENAPCRPLRRRRKVKRVASEVAASLQQKLKVSDWSYERGCRFKSAKKQRLSRWKENTPWTSSGHGLCESAESRTFLSKTGRKERMECEAEGQKHGSDENMSESETSSVCSSSDTGLFTNDEGRQGDDEQSDWFYEGECVPGFTVHNLLPKWAPDHCTEVERMDSGLDKLSDSTFLLPSRPAQRGYHGRLNRLPGAAARCLRKGRRRLAGKETGISSLGTERIGHPVSDPRQTDFWLPSAG-----KRERHQFNPLSPLYSLDVLADASHRRCSPAHCSARQASVHWGPPCSRDIKRKRKPVASASFSSPSTGHPDVLEPAIPAQ---KPPDSEWLDGTSAAEKTTAFPPATFFKMPQEKSSGCS--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PE65-1", "uniprot_id": "GPT2L_MOUSE", "id": "Q6PE65-1", "name": "G patch domain-containing protein 2-like", "aln": "MDELVHDLASALEQTSEQSKLGELWEEMALSPRQQRRQLRKRRGRKRRSDFTHLAEHACCFSEASESSLDEATKDCREVAPLTNFSDSDDTVVAKRHPALSAIIRGKQHSWPESDSFTENAPCRPLRRRRKVKRVTSEVAASLQQKLKVSDWSYERGCRFKSAKKQRLSRWKENTPWTSSGHGLCESAENRTFLSQPGRKERMECEAEEQKHGSDENMSECDTSSVCSSSDTGLFTNDEGRQGDDEQSDWFYEGECVPGFTVHNLLPKWAPDHCTEVERMDSGLDKLSDPTFLLPSRPAQRGYHGRLNRLPGAAARCLRKGRRRLPGKEASMSSLGTERIGHTISDPRQTDFWLPSAG-----KRERNQFNPLSPLYSLDVLADASHRRCSPAHCSARQASVHWGPPCPRDIKRKRKPVASASFSSPSPVHPDVLEPAIPAQ---KPPDSEWLDGTSAAEKATAFPPATFFKMPQEKNSGCSSSPGTNGC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NWQ4-3", "uniprot_id": "GPT2L_HUMAN", "id": "Q9NWQ4-3", "name": "G patch domain-containing protein 2-like", "aln": "MDELVHDLASALEQTSEQNKLGELWEEMALSPRQQRRQLRKRRGRKRRSDFTHLAEHTCCYSEASESSLDEATKDCREVAPVTNFSDSDDTMVAKRHPALNAIVKSKQHSWHESDSFTENAPCRPLRRRRKVKRVTSEVAASLQQKLKVSDWSYERGCRFKSAKKQRLSRWKENTPWTSSGHGLCESAENRTFLSKTGRKERMECETDEQKQGSDENMSECETSSVCSSSDTGLFTNDEGRQGDDEQSDWFYEGECVPGFTVPNLLPKWAPDHCSEVERMDSGLDKFSDSTFLLPSRPAQRGYHTRLNRLPGAAARCLRKGRRRLVGKETSINTLGTERISHIISDPRQKEKNKALASDFPHISACAHEFNPLSPLYSLDVLADASHRRCSPAHCSARQANVHWGPPCSRDIKRKRKPVATASLSSPSAVHMDAVEPTTPASQAPKSPSSEWLVRTSAAEKATDATTATFFKMPQEKSPGYS--------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******************.**************************************:**:********************:*********:********.**::.***** ***********************:*****************************************************.*****:.*********:: **:********.:**************************************** ***********:***********:**.************** ******************** ***:.:.:******.* :*****.: . *. . ::*******************************.*******.***********:**:****. * *.:**: **. *.*.**** ******:* ..**********..* * ", "identical_positions": 402, "similar_positions": 51, "identity": "82.04%" }, { "cls_id": "homologset.agr.RGD:1308908", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "F1M8D7-1", "uniprot_id": "F1M8D7_RAT", "id": "F1M8D7-1", "name": "", "aln": "MTERASDSRRLLPGDGASSRGARAAGRMNRAKPTTVRRPSAAAKPSGHPPPGDFIALGSKGQANESKTASTLLKPAPSGLPSERKRDASASLSGASGLTGLTKRPKLSSTPPLSALGRLAEAAVAEKRAISPSIKEPSVVPIEVLPTVLLDEIEAAELEGNDDRIEGVLCGAVKQLKVT--RAKPDSTLYLSLMYLAKIKPNIFATEGVIEALCSLLRRDASVNFKAKGNSLVSVLACNLLMAAYEEDENWPEIFVKVYIEDSLGERIWVDSPHCRTFVDNIQTAFNTKMPPKSVLLQGEGARSGGELGAGSSPHPSLTEEEDSQTELLIAEEKLSPEQEGQLMPRPRYDELTESVEEYVLDMLRDQLNRRQPIDNVSRNLLRLLTATCGYKEVRLLAVQRLEMWLQNPKLTRPAQDLLMSVCMNCNSHGSEDMDVISHLIKIRLKPKVLLNHYMLCIRELLNAHKDNLGTTIKFVIFNELSNARNPNNMQILYTVLQHSSELAPKFLAMVFQDLLTNKDDYLRASRALLREIIKQTKHEINFQAFCLGLMQERK--EPQYLEMEFKERFVVHITDVLAVSMMLGITAQVKEAGVAWDK-GEKRNLEVLRTFQNQIAAIQRDAVWWLHTVVPSISKLAPKDYVHCLHKVLFTEQPETYYKWDNWPPESDRNFFLRLCSEVPILEDTLMRILVIGLSRELPLGPADAMELADHLVKRAAAVQADDVEVLKVERIQLIDAVLNLCTYHHPENIQLPPGYQPPNLAISTLYWKAWPLLLVVAAFNPENIGLAAWEEYPTLKMLMEMVMTNNYSYPPCTLTDEETRTEMINRELQISQREKQEILAFEGHLAAAST-KQTITESSSLLLSQLTSLDPQGPPRRPPPHILDQVKALNQSLRLGHLLCRSRNPDFLLHIIQRQASSQSMPWLADLVQSSEGSLDVLPVQCLCEFLLHDAADATASGEEDDEGESREQKAKKRQRQQKQRQLLGRLQDLLLGPKADEQTTCEVLDYFLRRLGSSQVASRVLAMKGLSLVLSEGGLRDKEEKEPPMEEDVGEADALQGYQWLLRDLPRLPLFDSVRTTTALALQQAIHMETDPQTISAYLIYLSQHTPVEEQGPHSDLALDVARLVVERSTIMAHLFSKPS--CSTASDAVLSALLSVFSRYVRRMRKSKEGEEVYSWSESQDQVFLRWTSGETATMHILVVHAMVILLTLGPPRSGDSEFSELLDIWFPEKKPLPTAFLVDTS-EEALLLPDWLKLRMIRSEVPRLVDAALQDLEPQQLLLFVQSFGIPVSSMSKLLQYLDQAVAQDPQTLEQNIMDKNYMAHLVEVQHERGASGGQTFHSLLTASLPPRRDSTEAPKPESSPEPPPGQGRTRAGTQVPVLGPEDDLAGIFLQIFPLSPDPRWQSSSPRPLALALQQALGQELARVRQGNPEVPGITVRLLQAMATLLSSPHGGTLALAMHHSHFLSCPLMRQLCQYQRAVPQDTGFSSLFLKVLMQILQWLDSPAVEDGPLQAQLKLFATRYSARRRISDVRSGLLHLAEALSFHRDLEVANSTARAVIATLRSGEKCTVEPELISKVLRGLIEVRSPHFEELLTALFSATAET-CPSPASGPIVVVSSLLLQERDEPLGPSTQDAEGASTEAMRLGPASGLLVDWLETLDPEVVCSCPDLQWKLLFSRRKGKGHISAQVLSFRPYLLALLTHQASWSTLHRCTRVLLSKSREQRLDPSASLDFLWACIHVPRIWQGRDQRTPQKRREELVLHVQGPELLSLVELILSEAETRSQDGDSAARTLIQTRLPLLLSCCRSNDESIGKVTEHLTSCIQQWGDSVLGQRCRDLLLQLYLQRPEVRVPVP-EVLLQSEGATSSSICKLDGLIHRFITLLADTSDSRSSESRVADANMACRKLAVAHPILLLRHLPMIAALLHGRTHLNFQEFRQQNHLAFYLHVLGILELLQPRVFQSEHQGALWDCLRSFIRLLLNYRKSSRQLAPFISKFVQFIHKYVACSAPAAVAFLQKHAEPLHDLSFDNSDLVMLKSLLAGLSLPSRDGRADQGLDEE-----------------------------------GEDERSAGSLPLVSVSLSTPLTVADVAPHMKRLS----RGQAVEDVLETLSDIDEMSRRRPEVLGFFSTNLQRLMSSAEESCRNLAFSLALRSIQNNP---SIAADFLPTFMYCLGSRDFEVVQTALRNLPEYTLLCQEHAAVLLHRAFLVGMYGQIDTSAQISEALKILHMEAVM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P4S8-1", "uniprot_id": "INT1_MOUSE", "id": "Q6P4S8-1", "name": "Integrator complex subunit 1", "aln": "---------------------------MNRAKPTTVRRPSAAAKPSGHPPPGDFIALGSKGQASESKTTSTLLKPAPSGLPSERKRDASASLSGTSALTGLTKRPKLSSTPPLSALGRLAEAAVAEKRAISPSIKEPSVVPIEVLPTVLLDEIEAAELEGNDDRIEGVLCGAVKQLKVT--RAKPDSTLYLSLMYLAKIKPNIFATEGVIEALCSLLRRDASVNFKAKGNSLVSVLACNLLMAAYEEDENWPEIFVKVYIEDSLGERIWVDSPHCRTFVDNIQTAFNTKMPPKSVLLQGEGARSGGELGAGSSPHPSLTEEEDSQTELLIAEEKLSPEQEGQLMPRPRYDELTESVEEYVLDMLRDQLNRRQPIDNVSRNLLRLLTATCGYKEVRLLAVQRLEMWLQNPKLTRPAQDLLMSVCMNCNSHGSEDMDVISHLIKIRLKPKVLLNHYMLCIRELLNAHKDNLGTTIKFVIFNELSNARNPNNMQILYTVLQHSSELAPKFLAMVFQDLLTNKDDYLRASRALLREIIKQTKHEINFQAFCLGLMQERK--EPQYLEMEFKERFVVHITDVLAVSMMLGITAQVKEAGVAWDK-GEKRNLEVLRTFQNQIAAIQRDAVWWLHTVVPSVSKLAPKDYVHCLHKVLFTEQPETYYKWDNWPPESDRNFFLRLCSEVPILEDTLMRVLVIGLSRELPLGPADAMELADHLVKRAAAVQADDVEVLKVERIQLIDAVLNLCTYHHPENIQLPPGYQPPNLAISTLYWKAWPLLLVVAAFNPENIGLAAWEEYPTLKMLMEMVMTNNYSYPPCTLTDEETRTEMINRELQISQREKQEILAFEGHLAAAST-KQTITESSSLLLSQLTSLDPQGPPRRPPPHILDQVKALNQSLRLGHLLCRSRNPDFLLHIIQRQASSQSMPWLADLVQSSEGSLDVLPVQCLCEFLLHDAADSTASGEEDDEGESREQKAKKRQRQQKQRQLLGRLQDLLLGPKADEQTTCEVLDYFLRRLGSSQVASRVLAMKGLSLVLSEGGLRDKEEKEPPMEEDIGETDALQGYQWLLRDLPRLPLFDSVRTTTALALQQAIHMETDPQTISAYLIYLSQHTPVEEQGPHSDLALDVARLVVERSTIMAHLFSKPS--CSTASDAVLSALLSVFSRYVRRMRKSKEGEEVYSWSESQDQVFLRWSSGETATMHILVVHAMVILLTLGPPRSGDSEFSELLDIWFPEKKPLPTAFLVDTS-EEALLLPDWLKLRMIRSEVPRLVDAALQDLEPQQLLLFVQSFGIPVSSMSKLLQYLDQAVAQDPQTLEQNIMDKNYMAHLVEVQHERGASGGQTFHSLLTASLPPRRDSTEAPKPESSPEPPPGQGRTRAGTQVPVLGPEDDLAGIFLQIFPLSPDPRWQSSSPRPLALALQQALGQELARVRQGNPEVPGITVRLLQAMTTLLSSPHGGTLALAMHHSHFLSCPLMRQLYQYQRAVPQDTGFSSLFLKVLMQILQWLDSPAVEDGPLQAQLKLFATRYSARHRISDVRSGLLHLADALSFHGDLEVANSTARAVIATLRSGEKCPVEPELISKVLRGLIEVRSPHLEELLTALFSATTETSCPSPASGPIVVVSSLLLQEKEELLGPSKQEVEGASTEAMRLGPASGLLVDWLETLDPEVVCSCPDLQWKLLFSRRKGKGHISAQVLSFRPYLLALLTHQASWSTLHCCIRVLLGKSREQRLDPSASLDFLWACIHVPRIWQGRDQRTPQKRREELVLHVQGPELLSLVELILSEAETRSQDGDSAARTLIQTRLPLLLSCCRSNDESIGKVTEHLTSCIQQWGDSVLGQRCRDLLLQLYLQRPEVRVPVP-EVLLQSEGATSSSICKLDGLVHRFITLLADTSDSRSSESRVADANMACRKLAVAHPVLLLRHLPMIAALLHGRTHLNFQEFRQQNHLAFFLHVLGILELLQPRVFQSEHQGALWDCLRSFIRLLLNYRKSSRHLAPFISKFVQFIHKYVGCSAPAAVAFLQKHAEPLHDLSFDNSDLVMLKSLLAGLSLPSRDGRTDQGLDEE-----------------------------------GEDERSAGSLPLVSVSLSTPLTVADVAPHMKRLS----RGRAVEDVLETLSDIDEMSRRRPEVLGFFSTNLQRLMSSAEESCRNLAFSLALRSIQNNP---SIAADFLPTFMYCLGSRDFEVVQTALRNLPEYTLLCQEHAAVLLHRAFLVGVYGQIDTSAQISEALKILHMEAVM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N201-1", "uniprot_id": "INT1_HUMAN", "id": "Q8N201-1", "name": "Integrator complex subunit 1", "aln": "---------------------------MNRAKPTTVRRPSAAAKPSGHPPPGDFIALGSKGQANESKTASTLLKPAPSGLPSERKRDAAAALSSASALTGLTKRPKLSSTPPLSALGRLAEAAVAEKRAISPSIKEPSVVPIEVLPTVLLDEIEAAELEGNDDRIEGVLCGAVKQLKVT--RAKPDSTLYLSLMYLAKIKPNIFATEGVIEALCSLLRRDASINFKAKGNSLVSVLACNLLMAAYEEDENWPEIFVKVYIEDSLGERIWVDSPHCKTFVDNIQTAFNTRMPPRSVLLQGEAGRVAGDLGAGSSPHPSLTEEEDSQTELLIAEEKLSPEQEGQLMPR--YEELAESVEEYVLDMLRDQLNRRQPIDNVSRNLLRLLTSTCGYKEVRLLAVQKLEMWLQNPKLTRPAQDLLMSVCMNCNTHGSEDMDVISHLIKIRLKPKVLLNHFMLCIRELLSAHKDNLGTTIKLVIFNELSSARNPNNMQVLYTALQHSSELAPKFLAMVFQDLLTNKDDYLRASRALLREIIKQTKHEINFQAFCLGLMQERK--EPQYLEMEFKERFVVHITDVLAVSMMLGITAQVKEAGIAWDK-GEKRNLEVLRSFQNQIAAIQRDAVWWLHTVVPSISKLAPKDYVHCLHKVLFTEQPETYYKWDNWPPESDRNFFLRLCSEVPILEDTLMRILVIGLSRELPLGPADAMELADHLVKRAAAVQADDVEVLKVGRTQLIDAVLNLCTYHHPENIQLPPGYQPPNLAISTLYWKAWPLLLVVAAFNPENIGLAAWEEYPTLKMLMEMVMTNNYSYPPCTLTDEETRTEMLNRELQTAQREKQEILAFEGHLAAAST-KQTITESSSLLLSQLTSLDPQGPPRRPPPHILDQVKSLNQSLRLGHLLCRSRNPDFLLHIIQRQASSQSMPWLADLVQSSEGSLDVLPVQCLCEFLLHDAVDDAASGEEDDEGESKEQKAKKRQRQQKQRQLLGRLQDLLLGPKADEQTTCEVLDYFLRRLGSSQVASRVLAMKGLSLVLSEGSLRDGEEKEPPMEEDVGDTDVLQGYQWLLRDLPRLPLFDSVRSTTALALQQAIHMETDPQTISAYLIYLSQHTPVEEQAQHSDLALDVARLVVERSTIMSHLFSKLS--PSAASDAVLSALLSIFSRYVRRMRQSKEGEEVYSWSESQDQVFLRWSSGETATMHILVVHAMVILLTLGPPRADDSEFQALLDIWFPEEKPLPTAFLVDTS-EEALLLPDWLKLRMIRSEVLRLVDAALQDLEPQQLLLFVQSFGIPVSSMSKLLQFLDQAVAHDPQTLEQNIMDKNYMAHLVEVQHERGASGGQTFHSLLTASLPPRRDSTEAPKPKSSPEQPIGQGRIRVGTQLRVLGPEDDLAGMFLQIFPLSPDPRWQSSSPRPVALALQQALGQELARVVQGSPEVPGITVRVLQALATLLSSPHGGALVMSMHRSHFLACPLLRQLCQYQRCVPQDTGFSSLFLKVLLQMLQWLDSPGVEGGPLRAQLRMLASQASAGRRLSDVRGGLLRLAEALAFRQDLEVVSSTVRAVIATLRSGEQCSVEPDLISKVLQGLIEVRSPHLEELLTAFFSATADAASPFPACKPVVVVSSLLLQE-EEPLAGGKPGADGGSLEAVRLGPSSGLLVDWLEMLDPEVVSSCPDLQLRLLFSRRKGKG--QAQVPSFRPYLLTLFTHQSSWPTLHQCIRVLLGKSREQRFDPSASLDFLWACIHVPRIWQGRDQRTPQKRREELVLRVQGPELISLVELILAEAETRSQDGDTAACSLIQARLPLLLSCCCGDDESVRKVTEHLSGCIQQWGDSVLGRRCRDLLLQLYLQRPELRVPVP-EVLLHSEGAASSSVCKLDGLIHRFITLLADTSDSRALENRGADASMACRKLAVAHPLLLLRHLPMIAALLHGRTHLNFQEFRQQNHLSCFLHVLGLLELLQPHVFRSEHQGALWDCLLSFIRLLLNYRKSSRHLAAFINKFVQFIHKYITYNAPAAISFLQKHADPLHDLSFDNSDLVMLKSLLAGLSLPSRDDRTDRGLDEE-----------------------------------GEEESSAGSLPLVSVSLFTPLTAAEMAPYMKRLS----RGQTVEDLLEVLSDIDEMSRRRPEILSFFSTNLQRLMSSAEECCRNLAFSLALRSMQNSP---SIAAAFLPTFMYCLGSQDFEVVQTALRNLPEYALLCQEHAAVLLHRAFLVGMYGQMDPSAQISEALRILHMEAVM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W1C5-1", "uniprot_id": "INT1_DROME", "id": "Q9W1C5-1", "name": "Integrator complex subunit 1", "aln": "---------------------------MDRGKGSGSNRS-----QKKVPLGGELFALG-KSVRDDSKSKILPIKGMSS---SDRKREASTALASSSKR----------------FRGNLKDAGAPDMSSGSSQCETWEQFAVDCDLDTVVETIYAALEQNDSETVGRLVCGVIKQTTTSSSRSKVDNIALLALIYVAKVQPSIFCTDIVACALLSFLRREANVKMRYNTN--LHILFANLLTRGFMEISQWPEVLLRIYIDDAVNERYWADNELCAPLVKNICAAFKTRTPHISLLRWDVSSSLPSGQAHRDSMTVDDDSGDNSTQSLDASPLNTESEPIPDAMCTTKSRFSDAVVQKHVSDAIRDQLNKRQQQDNYTRNFLKFLCTTSGIAEVRCLSISRLELWIHNGKLVKFAQQLLSYICFNIKGRNTQDNEVLLVLVKMRLKTKPLINHYMSCLKEMIFLQPEILSTVMKLVVQNELSNTRNPNNMGMLATMFQTSADQSAATLAEIYQEFLLQRDDCLRTLRVFLRELVRMLRFDVNLVKFCKTFLSEREDLTPQIEMFEFKERIFNSMVDIVCLCMFLSATPQAREASLSLKTNRDTKNNHALLKLYNQMSQIQLDTVSWMYETVPTLFKIPAAEYHQALHKLLLLDSPEQYSRCDQWPSEPERGAILRIISETPIHEETLLRIILIGITKDIPFSIANTFDVLLLVIKRVSGMKATNIPAVQANKFDIIDFLFSMSEYHHPENIRLPAEYEPPKLAIIAFYWKAWLILLMISAHNPSSFGAFCWDHYPTMKMMMEICITNQFNN-----------SSATKDELQIITMERDHILQFETYLAAQTSPHAVITEETAILITQLMLMDPMGTPRKVPSMVLDQLKFLNQTYKLGHLFCRCRKPDLLLDIIQRQGTTQSMPWLSDLVQNSEGDFSHLPVQCLCEFLLFNAHIINEENSRD-------------------AELVNFLRNLIFDGNLSHQIVCELLDYIFRRLSSTVKQSRVAALSGLKIIFRHSGDFEN--------------------EWLLKSLQQIPHFYEVKPFIIPQLRAACQVENCPELIMAYIQFITAHTLNDPVNEMLDHVIDMAQLIVERSTMFQHIIISQEDYDYVPDENRIQTLKCLFVMFNNYIIKLREYHEPYEWTEYPDLLMVQFDDGVQLPLHINIIHAFIILLTYS--NSNMPESIPILDYWFPPGRPAPVAFLPSMPQEQVQLLPDWLKLKMIRSSVDRLIEAALNDLTPDQIVLFVQNFGTPVNSMSKLLAMLDTAVLEQFDLVKNAILNKAYLAQLIEIQQARGAKNG--------------HYTVQALDLHSHSQTVPDLPKISVVIQEAVEIDDYDSS----------------DSDDRPTNFLATKEVAQTILTQPDQLTESRSDCRSLIQKLLDMLASPNSNRADVVNAITEVLAVGCSVTMSR----------HACTFLRTFFSCMLHSDKYHILENALQKNLSMFKHTFADSSLLQ--------------------------------------------------------KSELYHESLVFMLRNSREIYAQQFKANTALVARKRIVRAIVQSFDQTKDSKTVAKSKSDQLFHN-GLFIDWLSEMDPEIVS-TQLMKERFLFSKS---------CSEFRFYLLSLINHQTNWDTIERIAEYLFKN-FHEDYDYATVLNYFEALTTNPKLWKGRDKYMSKNVRPDAFFMLRTSELEPFSHFILHEGLSEVKLDSKNYDFKLCSRMNLLFKLTEKRRDLMVKVMEHVE------KSSVSDYLKLQVLQQMYIMYPRIKFLKPGKTGEQAYKLQNLKGCQADKVSNNLITCLGSLVGKKDFETLSTDTELLLRKLAASHPLLFLRQLGVLSSIMQGRAQLSMKALREEHHFHRFVQILRTLELLQPTIFEEAYKNEIQNTLSCYFNFFKHHSN-VKEACQMLNKFVQMLQAYINYNPSSALLFIEQYVGILKELAAKYTSLGKLQVLVQAVALLQHKSHSATELDDEEVKYEYDLDEHFDVKPSASKPVVTEDPIEVNPQTPIDPSSSRGPLSVLTLGSYSRSNYTDISPHFLDLVKIIKQSNTEDVVLGPMQELECLTSKRFVFINELFERLLNLIFSPSAQIRSIAFIILIRHLKHNPGNSDINLCTLNAYIQCLRDENSSVAATAIDNLPEMSVLLQEHAIDILTVAFSLGLKSCLNTGHQIRKVLQTLVIQHGY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:*.* : .*. . * *:::*** *. .:**: :* .* *:***:*:::*:.:* *.* :*...: : *.. : . ..:: .::: * ** :.:.: : ::**.:** ..: *:* *. *:*:*:**::*.**.*: * ** *:***:*.:::: : * : :* .*** .: * .:***:::::**:*::.** *.*. * .:*.** :**:*: * *:* . .. . . .* . . ::* .* : : ..* : * *:::* * :*****:** ** :**:*::* :*.* *** *::.:**:*::* **.: **:** :*:* : :.::* :*: *:*:***.* *:**:* *::*:: : : *.*.:*:*: ****.:****** :* * :* *:: :. ** ::*::* ::** **: *.:***::: :.::*: ** ::.**: ** :*****:. :.*::.:.*:*. *.*.:**.:: .. :.:* ..* .: **:: ** *:* *:: .**:: *:.. :* :.***:*: :.** * : *:**.*.:*. :**: **.** *:**:*:::**:::::*:. *::::: ::**.:.::* :: .::. : ::** ::.:. *******:**. *:**:*** ::***** :**:::*.**..:* .*:.***:**:**: :**::. :. : *** *::.** ** :*** :: : .***.:::*::** :** *.**: *. :***:* ***: :****:**.*:**:**.*****.::******:****.***.:. ***********.:* ....* :*:. *::*::. : ..* .**:***::***.*: *** *:.**.::: ... : :***:.* ::* * .*:. *: * ::*. *: * **: ::: ** : * .:*:*:*:*****:: *:: . . ...: :.:* .:* : . : : :* .* *.*:* * ::::: .* .:** ::**::**** . .:. .* :** *** :* *.*** . . *:. ********:****.* **::***:** *:*::****.** **.****** ** ** .: : ::: *::* *:*:*:*:*: ***..* : :.:* . .* .: . : . * * : * : .*. ** : : :.* : : .* . ::* : :*:**:.. : :..*: : : .:. **:.::. : *. : ..*: :* :: : :. :* .* *. :: : : . . . :*. . ::: : : . .. :: :* **::***. :***:*. :: ::***: .** ***:*:.**:.* *:. . *: : .: * :: *::: * *::*:***: .:: * : .: :: .** .: .:** *. :. : ... : :*: **:. : : ** **: .** . ::* *:*: *.::. * :. :: . . *: * : :.:** *.. ..: *. :*:.: ****.:**:*:**:* :::::::**::*.:: :*:::*: ::::* ****** :*.. ::. : : * .::.:: :: : :. . ::.****::: *: ...:*: *::::. *::*: . :.* *: *: .::* .:..:: **:* : . * *.*.::::. : . ::::*:: * :..: : :* :.::: :: :* .:. : .* .*: *.. *.:** : :* :::.* .* * ::: ** ..: .*. **: **** ::* **** :* ** :*: . ::.. ** :.*: * :: ", "identical_positions": 619, "similar_positions": 799, "identity": "27.22%" }, { "cls_id": "homologset.agr.RGD:1308910", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D0S9-1", "uniprot_id": "HINT2_MOUSE", "id": "Q9D0S9-1", "name": "Adenosine 5'-monophosphoramidase HINT2", "aln": "--------------------------MAAAVLLAVGLRAARRTLAAAGARGAQVRGNAGVSDGSEVAKAQKAAPGGASPTIFSRILDRSLPADILYEDQQCLVFRDVAPQAPVHFLVIPRKPIPRISQAEEDDQQLLGHLLLVAKKIAQAQGLKDGYRLVVNDGKMGAQSVYHLHIHVLGGRQ------LQWPPG----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4AB01-1", "uniprot_id": "D4AB01_RAT", "id": "D4AB01-1", "name": "", "aln": "MTCTTGPAPPAVTANGAAPAGDKLGKMAAAVLLAVGMRAAHRTLAAAGSRGAQVRGNAGMSDGSEVAKAQKAVPGGAAPTIFSRILDRSLPADILYEDQQCLVFRDVAPQAPVHFLVIPRKPIPRISQAEEDDQQLLGHLLLVAKKIAQAEGLKDGYRLVVNDGKMGAQSVYHLHIHVLGGRQ------LQWPPG----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BX68-1", "uniprot_id": "HINT2_HUMAN", "id": "Q9BX68-1", "name": "Adenosine 5'-monophosphoramidase HINT2", "aln": "--------------------------MAAAVVLAAGLRAARRAVAATGVRGGQVRGAAGVTDGNEVAKAQQATPGGAAPTIFSRILDKSLPADILYEDQQCLVFRDVAPQAPVHFLVIPKKPIPRISQAEEEDQQLLGHLLLVAKQTAKAEGLGDGYRLVINDGKLGAQSVYHLHIHVLGGRQ------LQWPPG----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q04344-1", "uniprot_id": "HNT1_YEAST", "id": "Q04344-1", "name": "Adenosine 5'-monophosphoramidase HNT1", "aln": "---------------------------MEPLISAPYLTTTKMSAPAT----------------------------LDAACIFCKIIKSEIPSFKLIETKYSYAFLDIQPTAEGHALIIPKYHGAKLHDIP---DEFLTDAMPIAKRLAKAMKLDT-YNVLQNNGKIAHQEVDHVHFHLIPKRDEKSGLIVGWPAQETDFDKLGKLHKELLAKLEGSD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:: * : ::: : .*: :. **.:*:. .:*: * * : . .* *: * * * *:**: .:: : :::* . : :**: *:* * *.:: *:**:. *.* *:*:*:: *: : **. ", "identical_positions": 34, "similar_positions": 51, "identity": "15.67%" }, { "cls_id": "homologset.agr.RGD:1308911", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4A532-1", "uniprot_id": "D4A532_RAT", "id": "D4A532-1", "name": "Homeobox protein MOX-1", "aln": "MDPVVNSCVRNPQPPAPVWGCLRNPHSEGSSASGLPHYPPTPFSFHQKSDFP--ATAAYPDFSTSCLAATPHSLPRAERIFNEQHPAFPQTPDWHFPISEAGQR---LNLGPAGSA-REMG-AGSPGLVDGTGGLGE-DCMVLGTIAHETEKKLSRRKKERSDNPENGGGKPEGSSKARKERTAFTKEQLRELEAEFAHHNYLTRLRRYEIAVNLDLSERQVKVWFQNRRMKWKRVKGGQPVSPQEQDPEDGDSAASPSSE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P32442-1", "uniprot_id": "MEOX1_MOUSE", "id": "P32442-1", "name": "Homeobox protein MOX-1", "aln": "MDPVANSCVRNPQPPAPVWGCLRNPHSEDSSASGLSHYPPTPFSFHQKSDFP--ATAAYPDFSASCLAATPHSLPRTERIFNEQHPAFPQTPDWHFPISEAGQR---LNLGPAGSA-REMG-AGSPGLVDGTAGLGE-DCMVLGTIANETEKKSSRRKKERSDNQENGGGKPEGSSKARKERTAFTKEQLRELEAEFAHHNYLTRLRRYEIAVNLDLSERQVKVWFQNRRMKWKRVKGGQPVSPQEQDREDGDSAASPSSE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P50221-1", "uniprot_id": "MEOX1_HUMAN", "id": "P50221-1", "name": "Homeobox protein MOX-1", "aln": "MDPAASSCMRSLQPPAPVWGCLRNPHSEGNGASGLPHYPPTPFSFHQKPDFLATATAAYPDFSASCLAATPHSLPQEEHIFTEQHPAFPQSPNWHFPVSDARRR---PNSGPAGGS-KEMG-TSSLGLVDTTGGPGD-DYGVLGSTANETEKKSSRRRKESSDNQENRG-KPEGSSKARKERTAFTKEQLRELEAEFAHHNYLTRLRRYEIAVNLDLSERQVKVWFQNRRMKWKRVKGGQPISPNGQDPEDGDSTASPSSE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1Q4R9-1", "uniprot_id": "MEOX1_DANRE", "id": "F1Q4R9-1", "name": "Homeobox protein MOX-1", "aln": "MEQSASSCMRSPHTGGALWGCVRSPHSGGSGA-GIQPYQQAPFALHQKHDFL-----AYTDFSSSCLVPAPHAYPREDRLYPETHSGYQRT-EWQFSPCEPRGRGQEPCQGAAEAVGAEMDSAGGDRLAGAVTGCLEGDYSPQSVPAVDTEKKSSKRKREVTDIQ-DSSFKADSNCKARKERTAFTKEQLRELEAEFTHHNYLTRLRRYEIAVNLDLTERQVKVWFQNRRMKWKRVKGGQPASPHDLEADELDSAASPSSE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VCY0-1", "uniprot_id": "Q9VCY0_DROME", "id": "Q9VCY0-1", "name": "", "aln": "---------------------MKNSHAN--------VYQES---------------YCYEDITKSWLNQTEG--------YTDCSYVYDHSASSSYADYN----------------------------------------KLETNWCNEANDQWLQNEAPTGQELPSQRSKLRAISSNRKERTAFSKTQLKQLEAEFCYSNYLTRLRRYEIAVALELTERQVKVWFQNRRMKCKRIK---------LEEQQGSSAKTPF--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::..*: * : .* *:: * * : : : : :: . :. : . :::.: :.. : . * . .. *******:* **::***** : ************* *:*:************** **:* : :: .*: :* ", "identical_positions": 56, "similar_positions": 46, "identity": "21.46%" }, { "cls_id": "homologset.agr.RGD:1308913", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZHK9-1", "uniprot_id": "D3ZHK9_RAT", "id": "D3ZHK9-1", "name": "mRNA decay activator protein ZFP36", "aln": "-----MSTTLLSAFYDIDFLCKTEKSLANLNLN-NMLDKKAVGTPVAAAPSSSFTPGFLRRHSASN-------LHALAH--PSPGSCSPKFPGAPNG---SSCGPAGAGGPSSYGQLKEPSGGSGTALVNKESKFRDRSFSENGERSQHLLHLQQQQKGGSGSQINSTRYKTELCRPFEESGTCKYGEKCQFAHGFHELRSLTRHPKYKTELCRTFHTIGFCPYGPRCHFIHNADERRPAPSGG--ASGDLRAFGARDALHLGFAREPRPKLHHSLSFSGFPSGHHQPPGGLESPLLLDSPTSRTPPPPSCSSASSCSSSASSCSSTSAASTPSGAPTCCASAAAAAAAALLYGPGGAEDLLTPGAPCATCSTTSCANNAFTFGPELSSLITPLAIQTHNFAAAAAA-YYRSQQQGLAGLAPAPAQPPAAP---------APPSPPFGFQLPRRLSESPVFDAPPSPPDSLSDRDSYLSGSLSSGSLSGSESPSLDPGRRLPIFSRLSISDD----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P23949-1", "uniprot_id": "TISD_MOUSE", "id": "P23949-1", "name": "mRNA decay activator protein ZFP36L2", "aln": "-----MSTTLLSPFYDIDFLCKTEKSLANLNLN-NMLDKKAVGTPVAAAPSSSFTPGFLRRHSASN-------LHALAHPVPSPGSCSPKFPGAPNGGG-SSCGPAGGGGLASYGQLKEPSGGSGTALVTKESKFRDRSFSENGERSQHLLHLQQQQKGGSGSQINSTRYKTELCRPFEESGTCKYGEKCQFAHGFHELRSLTRHPKYKTELCRTFHTIGFCPYGPRCHFIHNADERRPAPSGGGGASGDLRAFGARDALHLGFAREPRPKLHHSLSFSGFPSGHHQPPGGLESPLLLDSPTSRTPPPPS-SSASSCSSSASSCSSASAASTPSGAPTCCAT---AAAAALLYGPGGAEDLLSPGAPCASCSS-SGANNAFAFGPELSSLITPLAIQTHNFAAAAAAAYYRNQQQGLTGPAPPPAQPPAAP---------APPSPPFGFQLPRRLSESPVFDAPPSPPDSLSDRDSYLSGSLSSGSLSGSESPSLDPGRRLPIFSRLSISDD----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P47974-1", "uniprot_id": "TISD_HUMAN", "id": "P47974-1", "name": "mRNA decay activator protein ZFP36L2", "aln": "-----MSTTLLSAFYDVDFLCKTEKSLANLNLN-NMLDKKAVGTPVAAAPSSGFAPGFLRRHSASN-------LHALAHPAPSPGSCSPKFPGAANG---SSCGSAAAGGPTSYGTLKEPSGGGGTALLNKENKFRDRSFSENGDRSQHLLHLQQQQKGGGGSQINSTRYKTELCRPFEESGTCKYGEKCQFAHGFHELRSLTRHPKYKTELCRTFHTIGFCPYGPRCHFIHNADERRPAPSGG--ASGDLRAFGTRDALHLGFPREPRPKLHHSLSFSGFPSGHHQPPGGLESPLLLDSPTSRTPPPPSCSSASSCSSSASSCSSASAASTPSGAPTCCASAAAAAAAALLYGTGGAEDLLAPGAPCAACSSASCANNAFAFGPELSSLITPLAIQTHNFAAVAAAAYYRSQQQQQQQGLAPPAQPPAPPSATLPAGAAAPPSPPFSFQLPRRLSDSPVFDAPPSPPDSLSDRDSYLSGSLSSGSLSGSESPSLDPGRRLPIFSRLSISDD----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P47976-1", "uniprot_id": "CTH1_YEAST", "id": "P47976-1", "name": "mRNA decay factor CTH1", "aln": "---MMPNVAPNSYYLNIPNANSTSTTTSSIFSDLNKEYESKIKEIEEYYIKTLLNENTDNDDSSSSEGHNINETDILSEYSPRPSPWLPSKPNCYHPLGDFKDLIISDSRPTNTLPINNPFAGNNNISTLATTEKKRKKRSLEVEINPTYTTSAFSLPLTAENLQKLSQVDSQSTGLPYTLPIQKTTKLEPCRRAPLQLPQLVNKTLYKTELCESFTIKGYCKYGNKCQFAHGLNELKFKKKSN---------------------------------------------------------NYRTKPCINWSKLGYCPYGKRCCFKHGDDKD--------------VEIYQNANDGRSKDTALTPLPTSLAPSNNDNITNLSKPRNLHTSVKALQRMTW---------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P47977-1", "uniprot_id": "CTH2_YEAST", "id": "P47977-1", "name": "mRNA decay factor CTH2", "aln": "MWAQLSYTRPESQKTDLTSLFSTDQEQNPLN---DYQYQINIRELEEYYNKTILNE--DNIQETSS--------EISSAVSFSP----PKNTNAIQPG------LLYDP------QLMNPFLPSAHLNSTAPTTFKKK---LEVQINPDYVPKSSQLPLTSQNLQQLSQQKPKND---ASFSSEKESSAQPKVKSQVQETP---KQLYKTELCESFTLKGSCPYGSKCQFAHGLGELKVKKSCK---------------------------------------------------------NFRTKPCVNWEKLGYCPYGRRCCFKHGDDND--------------IAVYVKA--GTYCNVSSTSKQSDEKRSNG---RGSAKKKNLNVKVKALQRMTW---------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P47980-1", "uniprot_id": "TIS11_DROME", "id": "P47980-1", "name": "Protein TIS11", "aln": "---MSADILQKSREQDDSHYFERGDISKYVTMN-DHLGDFDCNEVRKEIRMLLAHGANLDQQHQQQ-------------------------PHRHHGG-----LTRTISQPAQLIQQQQQQHQQQQQQQPAVASLVTITENLGNMNLHRKLERTQSEPLPPQQPMNTSRYKTELCRPFEEAGECKYGEKCQFAHGSHELRNVHRHPKYKTEYCRTFHSVGFCPYGPRCHFVHNADEARAQQAAQ------------------------------------------AAKSSTQSQSQSQQSSSQNFSPKSNQSSNQSSNSSSSSSSSGGGGGGGNSINNNNGSQFYLPLSPPLSMSTGSDRESPTGSLSLSPTNSLTSFPFHDALQHGYLASNGAKSNSSASSTSSASGMGLGMSMGIGQGMIIGQGLGMG-------HHGPATPPESPNVPISPVHTP---PPYDVVVSGSGAGNNSVGSKQLLQKSVSTPMQQEDTPRLPVFNRLSSGVEAYQQQSNLGL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : . : : . . .. . : : . . : :: ..: * . :. : : **** *.:* * * ** :*:* *. .* : . :. . . .. . .. . .. . . . : . : . : . . ", "identical_positions": 16, "similar_positions": 54, "identity": "3.07%" }, { "cls_id": "homologset.agr.RGD:1308914", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AGW5-1", "uniprot_id": "A0A8I6AGW5_RAT", "id": "A0A8I6AGW5-1", "name": "", "aln": "----------------------------------------------------------MVVPGPLALSLLLPSFTLLLSHLSTSQDITSEPSSEQQ--LCTRREHPIVAFEDLKPWVSNFTYPGVRDFSQLALDPSRNQLIVGARNYLFRLSLANVSLLQATEWASSEDTRRSCQSKGKTEEECQNYVRVLIVSG-RKVFMCGTNAFSPVCSSRQVGNLSRAIEKINGVARCPYDPRHNSTAVISSQGELYAATVIDFSGRDPAIYRS--LGSGPPLRTAQYNSKWLNEPNFVAAFDIGLFAYFFLRENAVEHD-CGRTVYSRVARVCKNDVGG-RFLLEDTWTTFMKARLNCSRPGEVPFYYNELQSAFHLPEQDLIYGVFTTNVNSIAASAVCAFNLSAISKAFNGPFRYQENPRAAWLPIAN-PIPNFQCGTLPETGPNENLTERSLQDAQRLFLMSEAVQPVTPEPCVTQDSVRFSHLVVDLVQAKDTLYHVLYIGTESGTILKALSTASRSLRGCYLEELHVLPPGRLEPLRSLRILHSARALYVGLSDRVLRVPLERCSAYLSQGACLGARDPYCGWDGKRQLCS-TLEDSSNMSLWIQN-ITACPVRNVTRDGGFGPWSPWKPCEHLDG-DNSGSCLCRARSCDSPRPRCGGLECLGPAIHIANCSRNGAWTAWSSWAQCSTSCGIGFQVRQRSCSNPAPRHGGRICVGKSREERFCNENTPCPVP------IFWASWGSWSKCSSNCGGGVQSRRRSCEN------GNSCPGCGVVRSPGWGAGCRETYRPGESETTFTPKEFKTCNPEACPEVRRNTPWTPWLPVNVTQGG--ARQEQRFRFTCRAPLPDPHGLQFGKRRTETRTCPA-DGTGACDTDALVEDLLRSGSTSPHTLSGGWATWGLWSSCSRDCELGFRVRKRTCTNPEPRNGGLPCVGDAAEYQDCNPQACPVRGAWSCWTAWSQCSASCGGGHYQRTRSCTSPAPSPGEDICLGLHTEEALCATQACP--EGWSLWSEWGVCTEDGAQSRSRSCEELVPGPGACVGNSSQSRPCPYSEIPVILPASSVEETASCGGFSLIHLIVTGVSCFLGSGLLTLAVYLSCQHCQRQSQESTLVHPATPNHLHYKSG-----GTPKNEKYTPMEFKTLNKNNLIP-DDRATFYP--LQQTNVYTTTYYPSPLNKPNFRPEASPGQR-CFPNS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60519-1", "uniprot_id": "SEM5B_MOUSE", "id": "Q60519-1", "name": "Semaphorin-5B", "aln": "----------------------------------------------------------MVVPGPLALSLLLSSLTLLVSHLSSSQDIASESSSEQQ--MCTRREHPIVAFEDLKPWVFNFTYPGVRDFSQLALDPSRNQLIVGARNYLFRLSLANVSLLQATEWASSEDTRRSCQSKGKTEEECQNYVRVLIVSG-RKVFMCGTNAFSPVCSSRQVGNLSRTIEKINGVARCPYDPRHNSTAVISSQGELYAATVIDFSGRDPAIYRS--LGSGPPLRTAQYNSKWLNEPNFVAAFDIGLFAYFFLRENAVEHD-CGRTVYSRVARVCKNDVGG-RFLLEDTWTTFMKARLNCSRPGEVPFYYNELQSAFHLPEQDLIYGVFTTNVNSIAASAVCAFNLSAISKAFNGPFRYQENPRAAWLPIAN-PIPNFQCGTLPETGPNENLTERSLQDAQRLFLMSEAVQPVTPEPCVTQDSVRFSHLVVDLVQAKDTLYHVLYIGTESGTILKALSTASRSLRGCYLEELHVLPPGRLEPLRSLRILHSARALFVGLSDRVLRVPLERCSAYHSQGACLGARDPYCGWDGKRQLCS-TLEDSSNMSLWIQN-ITTCPVRNVTRDGGFGPWSPWKPCEHLDG-DNSGSCLCRARSCDSPRPRCGGLECLGPSIHIANCSRNGAWTAWSSWAQCSTSCGIGFQVRQRSCSNPAPRHGGRICVGKSREERFCNENTPCPVP------IFWASWGSWSKCSNNCGGGVQSRRRSCEN------GNSCPGCGV--------------------------EFKTCNPEACPEVRRNTPWTPWLPVNVTQGG--ARQEQRFRFTCRAPLPDPHGLQFGKRRTETRTCPA-DGTGACDTDALVEDLLRSGSTSPHTLNGGWATWGPWSSCSRDCELGFRVRKRTCTNPEPRNGGLPCVGDAAEYQDCNPQACPVRGAWSCWTAWSQCSASCGGGHYQRTRSCTSPAPSPGEDICLGLHTEEALCSTQACP--EGWSLWSEWGVCTEDGAQSRSRSCEELLPGPGACVGNSSQSRPCPYSEIPVILPASSVEETTSCGGFNLIHLIVTGVSCFLVSGLLTLAVYLSCQHCQRQSQESTLVHPATPNHLHYKGG-----GTPKNEKYTPMEFKTLNKNNLIP-DDRANFYP--LQQTNVYTTTYYPSPLNKPSFRPEASPGQR-CFPNS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P283-1", "uniprot_id": "SEM5B_HUMAN", "id": "Q9P283-1", "name": "Semaphorin-5B", "aln": "MPCGFSPSPVAHHLVPGPPDTPAQQLRCGWTVGGWLLSLVRGLLPCLPPGARTAEGPIMVLAGPLAVSLLLPSLTLLVSHLSSSQDVSSEPSSEQQ--LCALSKHPTVAFEDLQPWVSNFTYPGARDFSQLALDPSGNQLIVGARNYLFRLSLANVSLLQATEWASSEDTRRSCQSKGKTEEECQNYVRVLIVAG-RKVFMCGTNAFSPMCTSRQVGNLSRTIEKINGVARCPYDPRHNSTAVISSQGELYAATVIDFSGRDPAIYRS--LGSGPPLRTAQYNSKWLNEPNFVAAYDIGLFAYFFLRENAVEHD-CGRTVYSRVARVCKNDVGG-RFLLEDTWTTFMKARLNCSRPGEVPFYYNELQSAFHLPEQDLIYGVFTTNVNSIAASAVCAFNLSAISQAFNGPFRYQENPRAAWLPIAN-PIPNFQCGTLPETGPNENLTERSLQDAQRLFLMSEAVQPVTPEPCVTQDSVRFSHLVVDLVQAKDTLYHVLYIGTESGTILKALSTASRSLHGCYLEELHVLPPGRREPLRSLRILHSARALFVGLRDGVLRVPLERCAAYRSQGACLGARDPYCGWDGKQQRCS-TLEDSSNMSLWTQN-ITACPVRNVTRDGGFGPWSPWQPCEHLDG-DNSGSCLCRARSCDSPRPRCGGLDCLGPAIHIANCSRNGAWTPWSSWALCSTSCGIGFQVRQRSCSNPAPRHGGRICVGKSREERFCNENTPCPVP------IFWASWGSWSKCSSNCGGGMQSRRRACEN------GNSCLGCGV--------------------------EFKTCNPEGCPEVRRNTPWTPWLPVNVTQGG--ARQEQRFRFTCRAPLADPHGLQFGRRRTETRTCPA-DGSGSCDTDALVEVLLRSGSTSPHTVSGGWAAWGPWSSCSRDCELGFRVRKRTCTNPEPRNGGLPCVGDAAEYQDCNPQACPVRGAWSCWTSWSPCSASCGGGHYQRTRSCTSPAPSPGEDICLGLHTEEALCATQACP--EGWSPWSEWSKCTDDGAQSRSRHCEELLPGSSACAGNSSQSRPCPYSEIPVILPASSMEEATDCAGFNLIHLVATGISCFLGSGLLTLAVYLSCQHCQRQSQESTLVHPATPNHLHYKGG-----GTPKNEKYTPMEFKTLNKNNLIP-DDRANFYP--LQQTNVYTTTYYPSPLNKHSFRPEASPGQR-CFPNS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QPQ6-1", "uniprot_id": "F1QPQ6_DANRE", "id": "F1QPQ6-1", "name": "Semaphorin-5A", "aln": "------------------------------------------------MTVLPRDVASLAVPGLILCFITLPFPTILSQNPPVPTETSPSPAPHHTRPECTRLEHPVVSIQALSPLISSFSHPGVRDYSQLTLDLTRNELIVGARNYLFRLNLSNISLIQATEWGPDEDTRRSCQSKGKTELECQNYIRVLLVNK-TEVVTCGTNAFQPLCITREAGNMSRVLERVNGVARCPYDPRHNSTAVVTESGELYAATVIDFSGRDPVIYRS--LGGMPPLRTAQYNSKWLNEPHFISAYDVGLFTFFFLRENAVEHD-CGKTVYSRVARVCKNDIGG-RFLLEDTWTTFTKARLNCSRSGEIPFYYNELQSTFYLPEQDLIYGIFTTNVNSIAASAVCAYNLSAITQAFNGPFRSQENPRSTWLPTPN-PIPNFQCGTIDEEGPNERLTERSLQDAQRLFLMNDVVQPVSVDPLVWQDDVRFSKLVVDIVQGQDSLHHVMYIGTEYGTILKALATTNKSLQGCYLEEMQLFPPGLQQPILSLQILHGDRTLFVGLNDKVLKIPLARCSSYKTELMCLDARDPYCGWDRKQRRCT-TIEDSSNMSQWFQN-ITACPLRNQTTDGAYGPWAPWQPCSHDDG-EGTSTCLCRSRVCNSPPPRCGGKNCQGPTIEVSNCSRNGGWTPWSSWGQCSTSCEIGFEVRQRSCNNPSPRHGGRVCVGQSREQRFCNEKVSCPQP------IFWSSWSPWSKCSADCGGGVHSRSRNCEN------GNSCPGCAL--------------------------EYQACNLESCPEVRRNTPWTPWMPVNITQGG--ARQEQRVRYICRAQLADPHELQLGKRKVETRFCPN-DGMVTCETDSLVEELLRM--PGVRLSGTGWSSWEMWSACTQECAKGYRTRKRSCTNTDGKNIPTACRGSPVEYQDCNPQPCPVKGAWSCWSSWSQCSVPCGGGHYQRTRTCTSPAPANGGDICIGLHTEEALCNTHTCD--GGWMAWSVWSECDDSGLQLRSRVCGAQS---MPCAGNSSQHRDCN--EIPAILPASSYEKDQQCGGFTLLHLIATGVSCFLGAGLLSFLVYVYCQRFHKPSQESAIIHPTTPNHLNYKGN-----TTPKNEKYTPMEFKTLNKNNLLP-DERTNYFPSPLQQTNVYTTTYYPTGLGKYDYRPDSSPSPCRTYNHS-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AA52K968-1", "uniprot_id": "A0AA52K968_DANRE", "id": "A0AA52K968-1", "name": "Semaphorin-5A", "aln": "------------------------------------------------MAAMVFWAGSLSFVGLVIFHLLF-LPVVTSQTPSSPPDT-PDPQPE----ECRRKMHPVTSYTALSPWLFSFSVPGVNYYSPLTLDLSRSQLIVGARNHLFRLSLSNISLLQATEWGVDETTRRSCQSKGKTEDECQNYVRVLLLNG-SRLFTCGTNAFMPVCVTRPVTDISSVLDSISGVARCPYDPRHNSTAMITESGEVYAATVTDFSSRDPIIYRS--LGNMPPLRTAQYNSKWLNDPHFISAYEVSRFTYVFLRENAVEQD-CGKTVFSRVARMCQNDIGG-RFLLEDTWTTFMKARLNCSRSGDVPFYYHELQSTFYLPEQDLIYGVFTTNVNSIAASAVCAFNLSAITQAFNGPFRYQENPRTSWLSTPN-PIPNFQCGTVNDSGPGANLTERSLQDAQRLFLMSDVVQPISTDPLVMQDNIRFSKLAVDIVQGRDTLYHVMYIGTEYGTIIKALSTNNKSLRGCYLEEMNILPGNTQEAILNLQILHSDRSLFVGLPSRVLKIPLERCSNYITEQDCLGARDPYCGWDRKEKRCT-TIEDSSNMSQWSQD-ITKCPERNLTQDGGFSDWSTWQACNHDDGGEGISTCQCRTRACDHPRPQCGGLKCVGANIEVANCSRNGGWTPWSSWAECSTSCGIGFEVRQRSCNNPSPRHGGRVCVGQAREERLCNEKNPCPVP------MSWVSWSAWSKCSVACGGGVQSRVRTCEN------GNTCPGCPL--------------------------EYRACNLDSCAEVRRTTPWTPWYPVNVTQLG--ARQEQRVRYTCRALLADPHDLQLGKRKIETRLCPTTDGAAACETDGLVEDLLRMGRPVTRVQGAAWASWETWSTCSKECSKGFRTRKRSCAAPDGKSTPFACSGAPVEYQDCNTQPCPVKGAWSCWSSWSQCSTSCGGGHHQRSRSCSNPAPAYSGDICIGLHTEEVLCNTHECE--GGWGAWSEWAECNGEGLQLRARTCEISP---ASCLGNSTDQRQCR--PNESAVLSKGQKRSTNCGGFSLFHLVLTGACCFLGAVLLSILVYVYCQRLRKPPQESAVIHPSTPNHLHYKDNS----CAPKNDLYTPMEFKTLNKNNLLPPDESCNFFPSPLPQTNVYTTTYYPSPLGKYDFP--SMDSPC-SFMHS-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VTT0-1", "uniprot_id": "SEM5C_DROME", "id": "Q9VTT0-1", "name": "Semaphorin 5c", "aln": "-------------------------------------------------------MNMLILKLPKMFSQLWLLLILSLLTLEGPQPSTGSGYTTKSSVDLLENDSRYISYQDLMSTAKRFYDPETTWYSEMLFDVARNQVIVGARDTLYRMSFD-LEPLERASWGATPSEIAMCQAKGQSERWCRNYVRVLHSYGENQLYACGTNAFQPSCSWRQMENLT-VTGVDSGVVKCPFHPQANSTSLLQSNGQLFVGTATDFSGSDVAILRTGVESNKRFLRTKQYNNNWLSGAQFVGSFEAGHFVYFLLRESAAEHMSCGKVIYSRVARVCKNDVGGGGQLLRDNWTSFLKARLNCSLPGEYPYYFDEIQGMTYAESESILYATFRTSGSSIFGSAVCAYNLSSINAAFDGPFKQQEHSDAAWKTVNTNQRSQFQCGTSSIG---------HWLESSRYQLMDEAVQPIGAEPLYHSKLEQFGRLALDIINTKTEQVHVLFVASSGNHIKKLSVKYDGDGVQTCLVELWQADDTGTSSLLNMAYLKVSDSLYLGTDLALTRIPAQHCSRHVSQSSCLNSMDPYCGWNELVERCMPQPQDSSVLQHWHQAPQITCPVLNAPIDGGWSTWSPWAVCQQHEQ--PDSNCQCRQRSCNNPQPQHGGATCEGISTQVTNCTQHGGWTEWSAWSPCSQTCGIAVKIRRRTCGNPRPAFGGRTCVGSEQSEMYCRHLPPCPVAKPQSVDGGWGPWGEWSECSAQCGGGFRMRRRECNDPAPLNGGMECPGCRL--------------------------DYEECNMQSCQEVRKLSAWTPWLTVTGSGNSSEPHMERRFRFVCRATSPDPSSVRIGLPKEESRNCHA-DGSCQRQVD----------------HDSADSDAADWSPCSVSCGGGVQQRHRGRGSQSRVCNIHACP-AEEQLSSNSLDNELEHGEWGCWSEWSACSVTCGLGLRRRTRRCLAGHDR----LCQGRALEEQKCEMVPCEDFLGWSAWSEWSSCSSDGIRLRHRRCLVEQPGSMECRGAEFEKTACVPNECEETQTAS----TATLPIVIFVGLLFTVACCLATYRFTKKRFMLSAEEALNKTTTTTASFDTYPNQYSSLPTKDYYDQRPKRQSSFRMPAKTSNLGNGNGTLNRNNMHQN--NTPKVLAKTYIDCESGTIKRQSALNNCRSNIDDEKF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : . . . : * . * * . :* : :* : .::*****: *:*:.: :. :: :.*. **:**::* *:**:*** .: ****** * * * ::: . .**.:**:.*: ***::: ..*:::..*. ***. * * *: .. *** ***.:**. .:*:.::: . *.:.:***.*.*: **:.::*****:*:**:** **.*.**:* ******* .*: *:*:.*:*. : .:.::*. * *. .** .*****:***:*. **:***: **:. ::* . . .:***** ::.* **.:.***: :* .. :*.:*.:*::: : **:::.:. . * * . . . * *: ..: .: *: :*::* : ::* :*: : :: **.: ******: . * :*** :. * * ** * . **.:. *:.* *.: : ..* ** * *: * *: ** * * .::**:::*.** **:*. ** :* *..::*:*:*.** * .*** ***. :.: *.. .** . * .*. **:** ****.: * * *:: * * ** : ::. ** :.* ***: :.**** .*. : . .: *:*.*: *** .** :::* : *:* * ** :.* . . : **.*: .* * : *:* . .* : .. . : :* *.**: ** **..** * :*:* * :* * ** * * ** ** *. * .* : * * * * * . : * :. . :. *: * .*: : . . : .:. . . :: . : **: **.: * ** * .* : . . .:* :.** .. . .. ", "identical_positions": 301, "similar_positions": 309, "identity": "24.77%" }, { "cls_id": "homologset.agr.RGD:1308915", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q3MHC1-1", "uniprot_id": "NAA60_RAT", "id": "Q3MHC1-1", "name": "N-alpha-acetyltransferase 60", "aln": "---------------------MTEVVPSSALSEVSLRLLCHDDIDTVKHLCGDWFPIEYPDSWYRDITSNKKFFSLAATYRGAIVGMIVAEIKNRTKIHKE---------------------DGDILASSFSVDTQVAYILSLGVVKEFRKHGIGSLLLESLKDHISTTAQDHCKAIYLHVLTTNNTAINFYENRDFRQHHYLPYYYSIRGVLKDGFTYVLYINGGHPPWTILDYIQHLGSALANLSPCSIPHRIYRQAHSLLCSFLPWSSISSKGGIEYSRTM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DBU2-1", "uniprot_id": "NAA60_MOUSE", "id": "Q9DBU2-1", "name": "N-alpha-acetyltransferase 60", "aln": "---------------------MTEVVPSSALSEVSLRLLCHDDIDTVKHLCGDWFPIEYPDSWYRDITSNKKFFSLAATYRGAIVGMIVAEIKNRTKIHKE---------------------DGDILASSFSVDTQVAYILSLGVVKEFRKHGIGSLLLESLKDHISTTAQDHCKAIYLHVLTTNNTAINFYENRDFRQHHYLPYYYSIRGVLKDGFTYVLYINGGHPPWTILDYIQHLGSALANLSPCSIPHRIYRQAHSLLCSFLPWSSISTKGGIEYSRTM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H7X0-1", "uniprot_id": "NAA60_HUMAN", "id": "Q9H7X0-1", "name": "N-alpha-acetyltransferase 60", "aln": "---------------------MTEVVPSSALSEVSLRLLCHDDIDTVKHLCGDWFPIEYPDSWYRDITSNKKFFSLAATYRGAIVGMIVAEIKNRTKIHKE---------------------DGDILASNFSVDTQVAYILSLGVVKEFRKHGIGSLLLESLKDHISTTAQDHCKAIYLHVLTTNNTAINFYENRDFKQHHYLPYYYSIRGVLKDGFTYVLYINGGHPPWTILDYIQHLGSALASLSPCSIPHRVYRQAHSLLCSFLPWSGISSKSGIEYSRTM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A3KPA3-1", "uniprot_id": "NAA60_DANRE", "id": "A3KPA3-1", "name": "N-alpha-acetyltransferase 60", "aln": "---------------------MTDVVPTTALSEIQLRLLCHDDIDRIKVLCGEWFPIEYPDSWYHDITSNKKFFSLAATFRGGIVGMIVAEIKSRTKVHKE---------------------DGDILASSFPVDTQVAYILSLGVVKEFRKHGIGSLLLDSLKEHISTTAQDHCKAIYLHVLTTNNTAIHFYENRDFKQHHYLPYYYSIRGVLKDGFTYVLYINGGHPPWTIFDYIHHIGSALASLSPCSIPQRIYRQAQNLLRSFLPWSGISSKSGIEYSRTM", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q95SX8-1", "uniprot_id": "NAA60_DROME", "id": "Q95SX8-1", "name": "N-alpha-acetyltransferase 60", "aln": "MAQFTLYNKHSAPPSSESTRVDCEHVPLCSINDVQLRFLVPDDLTEVRQLCQEWFPIDYPLSWYEDITSSTRFFALAAVYNLAIIGLIVAEIKPYRNVNKEVIANMSDSDELYTRLSGFPMQDKGILPDSMGRSADVGYILSLGVHRSHRRNGIGSLLLDALMNHLTTAERHSVKAIFLHTLTTNQPAIFFYEKRRFTLHSFLPYYYNIRGKGKDGFTYVNYINGGHPPWTLLDHIKHYASMVRHTS--SLCAWLAGRVQQVVRWFY-HKLLTRFNFIE-----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ** ::.::.**:* **: :: ** :****:** ***.****..:**:***.:. .*:*:****** :::** * .**...: .::*.******* :..*::*******::* :*::*: :. ***:**.****:.** ***:* * * :*****.*** ******* **********::*:*:* .* : * *: : :.:.:: * . :: . ** ", "identical_positions": 110, "similar_positions": 74, "identity": "38.73%" }, { "cls_id": "homologset.agr.RGD:1308916", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BGQ2-1", "uniprot_id": "CSRN2_MOUSE", "id": "Q8BGQ2-1", "name": "Cysteine/serine-rich nuclear protein 2", "aln": "-------------------------------------------------------------------------------------------------------------------------MDAFSGSGLKRKFDDVD--------------VGSSVSN---SDDEMSSSDSADSCDSLN-----------------------------PPTTASFTPTSILKRQKQ-LRRKN----------------------------------------------------------------------VRFDQVTVYYFARRQGFTSVPSQGGSSLGMAQRHNSVRSYTLCEFAQEQEVNHREILREHLKEEKLHAKKMKLTKNGTVESVEADGLTLDDVSDEDIDVENVEVDDYFFLQPLPTKRRRALLRASGVHRIDAEEKQELRAIRLSREECGCDCRLYCDPEACACSQAGIKCQVDRMSFPCGCSRDGCGNMAGRIEFNPIRVRTHYLHTIMKLELESKRQVSR----PAAEE-EPLP-------------GAQSSQTQDFQE-----FIAENETAVMHLQSAEELER----------LKAEEDSSGSSASLDSSMESLGVCILEEPLAVP-----------------QELCPGLAAP-ILIQAQLPPGSSVLCFTENSEHPAASPMSSPSYLNSGPLVYYQVEQ----------------RPVVGVKAESGSEEGPASFPKEKDLSVFSLPVTS--------------------LVACGPSASAALCKPEVGKTSSLNKLLPEDCGLKEPES---EDLHPSWSPSSLPFRTDNEEGCG-VQNSQQSEDRTSEDSALELPLAV-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A1W4-1", "uniprot_id": "D4A1W4_RAT", "id": "D4A1W4-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------MDAFSGSGLKRKFDDVD--------------VGSSVSN---SDDEMSSSDSADSCDSLN-----------------------------PPTTASFTPTSILKRQKP-LRRKN----------------------------------------------------------------------VRFDQVTVYYFARRQGFTSVPSQGGSSLGMAQRHNSVRSYTLCEFAQEQEVNHREILREHLKEEKLHAKKMKLTKNGTVESVEADGLTLDDVSDEDIDVENVEVDDYFFLQPLPTKRRRALLRASGVHRIDAEEKQELRAIRLSREECGCDCRLYCDPEACACSQAGIKCQVDRMSFPCGCSRDGCGNMAGRIEFNPIRVRTHYLHTIMKLELESKRQVSR----PAAAEDEPLP-------------GAQSSETQDFQE-----FIAENETAVMHLQSAEELER----------LKAEEDSSGSSASLDSSMESLGVCILEEPLAVP-----------------QELCPGLAAP-ILIQAQLPPGSSVLCFTENSEHPAASPMSSPSYLNSGPLVYYQVEQ----------------RPVVGVKAESGSEEGTASFPKEKDLSVFSLPVTS--------------------LVACSPSDSAALCKPEVGKAPSLNKLLPDDCNRKEPER---EDFHPSWSPSSLPFRTDNEEGCG-VQNSQQSEDRTPEDSALELPLAV-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H175-1", "uniprot_id": "CSRN2_HUMAN", "id": "Q9H175-1", "name": "Cysteine/serine-rich nuclear protein 2", "aln": "-------------------------------------------------------------------------------------------------------------------------MDAFTGSGLKRKFDDVD--------------VGSSVSN---SDDEISSSDSADSCDSLN-----------------------------PPTTASFTPTSILKRQKQ-LRRKN----------------------------------------------------------------------VRFDQVTVYYFARRQGFTSVPSQGGSSLGMAQRHNSVRSYTLCEFAQEQEVNHREILREHLKEEKLHAKKMKLTKNGTVESVEADGLTLDDVSDEDIDVENVEVDDYFFLQPLPTKRRRALLRASGVHRIDAEEKQELRAIRLSREECGCDCRLYCDPEACACSQAGIKCQVDRMSFPCGCSRDGCGNMAGRIEFNPIRVRTHYLHTIMKLELESKRQVSR----PAAPDEEPSPTASCSLT------GAQGSETQDFQE-----FIAENETAVMHLQSAEELER----------LKAEEDSSGSSASLDSSIESLGVCILEEPLAVP-----------------EELCPGLTAP-ILIQAQLPPGSSVLCFTENSDHPTASTVNSPSYLNSGPLVYYQVEQ----------------RPVLGVKGEPGTEEGSASFPKEKDLNVFSLPVTS--------------------LVACSSTDPAALCKSEVGKTPTLEALLPEDCNPEEPEN---EDFHPSWSPSSLPFRTDNEEGCGMVKTSQQNEDRPPEDSSLELPLAV-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AYP5-1", "uniprot_id": "A0A8M3AYP5_DANRE", "id": "A0A8M3AYP5-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------METVSSRGLKRRFEEVD--------------SGSPCSTPKDSDDDISSSDSADSCDSLN-----------------------------APS-SSLTPPSILRRHKVSLGRKQ----------------------------------------------------------------------VRFDAVTVYYFSRRQGFTSVPSQGGSSLGMARHHCAIRHYTLGEFAREQESSHKHVLRQHLRQEKLNARKLKLTRNGTVDCPEAELLTLDDISDEDLDVESVEVDDCFFLQPLPTKRRRALLRASGIARIDAREKAELRAIRLSREECGCDCRFYCDPRHCGCSQAGIKCQVDRMSFPCGCTRDGCGNSAGRIEFNPLRVRTHYLHTIMKLDLEKRTLLGVRSGEDCVEEAELVSSPSLSLSPLDSDVEVESQSIQELQEEQCDSLERENETAVLHLQSAEERERR---------LEQEEQQVEETQATDP-----TLCLLQGALTSQ-----------------AEMEGMERVEGVLLEGPFPEGATLLCITEN--HADEQTQQN-LLKDPASVLYYQVGH----------------VETAAFETLPAQVEEVVSEGGDPEME--------------------------------SDRQKQETCGQDSAKSLSVEVPPLLEDGSEE-----------QLSPEQASNDGECLETCL-----------ALDEKAVQLPPEV-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9U4G5-1", "uniprot_id": "Q9U4G5_DROME", "id": "Q9U4G5-1", "name": "", "aln": "MFSPIKKIFTYIQKNASGSNMFSPSGNKAAGQREGTTSLTAHDEGERKDQRHLDHKDNQSEPEERQHQLQIFPHLDDDDDDIERQIKTSIIDASKVHAAKAKALASLPMPLEQLDDELADFAHGPADTELEEQFLELENYPNNEIIVLGDADLNSSIASDAVSEDPLAIDNILDSASVTTNEEVDTSGELLWLKLNNETEMATRSAEVVSNNQASLEPAQPAKPKEDELRDGGSDSGLGSETSALLKDQAEKEAEPEIQKKVETKPIRSNLKRRLEDSESDAIDLVPDMSAPPVAPQKRTKRSINFDEVKVFYFPRQQGFSCVPTAGGCTLGMGARHVGFKTMTLAEHAAELR-----------RAHRSQNQELQPRGSSSDDSEESEEDYLSEGSGSDAEDG-----SNGFLQPVTPKQRRALLKAAGVRKIDASEKSECRDIRNSREVCGCSCREFCDPETCACSQAGIKCQVDRAMFPCGCTREACGNTVGRVEFNPTRVRTHYIHTVMRLDLEQRQGSVQGVQGGHLQPQQQQPSQQTIGYSPVGTAGSTSAYFLQTQSNYSSGYASPAYTPESSVSYYQQQVQQPGVPTAGQLIPQQQQAQSQSYAGYAQLDSLDSGLFASGSNATPSYGELYQSLSYGSTQITSYTAAYQQHSASPAVAVAPGAPSSCAYSSCAVPSVPPYGNATTTASSNVPYQTTAVSMTAASTSASPSRLVGNPVGSATASPATVSSSPATASGNEFISLSTPIASSSRLSQINDLLQHNRNTTAALVAVSEGLSGGRTSSSASTIDSIDTPPIVDDGQQRGCMSFEALPPPLVNPAPIVAVVENKLPPMALPAPHAPPSAPQPRQPLEQHHPATSESS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :. *:.:* ::: .*. :. *:* :: .: **.. . . . :*: *.. : :: * :.** *.*:**.*:***:.**: **.:***. :* ..: ** *.* * . : .: : :::: ..: :. *:: *.: *..* : . ****:..*:*****:*:*: :*** ** * * ** *** ***.** :***. *.************ *****:*:.*** .**:**** ******:**:*:*:**.: : . . : *. *. :. :: : : ::: .: : . :: . .. *:. * .. . . . .. : * . . . .. . : :: . . .. ::: : . :. .* : . ..:: . ", "identical_positions": 115, "similar_positions": 154, "identity": "13.25%" }, { "cls_id": "homologset.agr.RGD:1308917", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZZT8-1", "uniprot_id": "D3ZZT8_RAT", "id": "D3ZZT8-1", "name": "", "aln": "-MAVDIQPACLGLYCGKTLLFKNGSSEIYGECGVCPRGQRTNAQKYCQPCTESPELYDWLYLGFMAMLPLVLHWFFIEWYSGKK--SSSALFQHITALFECTMAAIITLLVSDPVGVLYIRSCRVLMLSDWYTMLYNPSPDYVTTVHCTHEAVYPLYTIVFVYYAFCLVLMMLLRPLLVKKIACGLGKSDRFKSIYAALYFFPILTVLQAVGGGLLYYAFPYIILVLSLVTLAVYMSASEIENCYDLLVRK-----KRLIVLFSHWLLHAYGIVSISRVDRLEHDLPLLALVPTPALFYLFTAKFTEP-------SRILSEGANGH----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BI36-1", "uniprot_id": "JKAMP_MOUSE", "id": "Q8BI36-1", "name": "JNK1/MAPK8-associated membrane protein", "aln": "-MAVDIQPACLGLYCGKTLLFKNGSSEIYGECGVCPRGQRTNAQKYCQPCTESPELYDWLYLGFMAMLPLVLHWFFIEWYSGKK--SSSALFQHITALFECTMAAIITLLVSDPVGVLYIRSCRVLMLSDWYTMLYNPSPDYVTTVHCTHEAVYPLYTIVFVYYAFCLVLMMLLRPLLVKKIACGLGKSDRFKSIYAALYFFPILTVLQAVGGGLLYYAFPYIILVLSLVTLAVYMSASEIENCYDLLVRK-----KRLIVLFSHWLLHAYGIVSISRVDRLEHDLPLLALVPTPALFYLFTAKFTEP-------SRILSEGANGH----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P055-4", "uniprot_id": "JKAMP_HUMAN", "id": "Q9P055-4", "name": "JNK1/MAPK8-associated membrane protein", "aln": "-MAVDIQPACLGLYCGKTLLFKNGSTEIYGECGVCPRGQRTNAQKYCQPCTESPELYDWLYLGFMAMLPLVLHWFFIEWYSGKK--SSSALFQHITALFECSMAAIITLLVSDPVGVLYIRSCRVLMLSDWYTMLYNPSPDYVTTVHCTHEAVYPLYTIVFIYYAFCLVLMMLLRPLLVKKIACGLGKSDRFKSIYAALYFFPILTVLQAVGGGLLYYAFPYIILVLSLVTLAVYMSASEIENCYDLLVRK-----KRLIVLFSHWLLHAYGIISISRVDKLEQDLPLLALVPTPALFYLFTAKFTEP-------SRILSEGANGH----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4KHY1-1", "uniprot_id": "A0A0B4KHY1_DROME", "id": "A0A0B4KHY1-1", "name": "JNK1/MAPK8-associated membrane protein", "aln": "MRMYDALERCPGAYCGRSPLGNNS----WSSCGVCPRGSRVNQSYACSPCRDELSTYSWLYLGFMTMLPLMMHCFFIDMDAKDRKFSRKQLILTASAFVEVAISAILATLLMEPMWELRLYACDVRKLTDWYTLFYNPSPNYEARVYCTQEAVYPLQTIVLVFYFLCLVNMFLIRPLVSKIMDVG-GRSK--APIYSALYFLPLLTFIHALGCGLIYYSFPYLSVAISMVANAIHYSL-KLDQTLKALVHSSVWELKNVVIIAVHWMLLAYGLTSLN------YHYAFMCLVPFPTLFYILTVRFTDPAEFRELESRIXCGDVQMQIFHARGTRRSTVVIYV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * * ***:: * :*. :..*******.*.* . *.** :. . *.*******:****::* ***: : .: * . *: :*:.* :::**:: *: :*: * : :* * *:****::*****:* : *:**:****** ***:::* :*** *:*:***: * : * *:*. .**:****:*:**.::*:* **:**:***: :.:*:*: *:: * :::: . **:. *.:::: **:* ***: *:. . .::.*** *:***::*.:**:* *** . ..: : ", "identical_positions": 129, "similar_positions": 104, "identity": "37.72%" }, { "cls_id": "homologset.agr.RGD:1308918", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4A415-1", "uniprot_id": "D4A415_RAT", "id": "D4A415-1", "name": "", "aln": "MMGEVEISIMAASISGYTFSAVCFHSANSNADHEGFLLGEVRQEETFSISDSQISNTEFLQVIEIHNHQPCSKLFSFYDYASKVNEESLDRILKDRRKKVIGWYRFRRNTQQQMSYREQVIHKQLTRVLGVPDLVFLLFSFISTANNSTHALEYVLFRPNR-RYNQRISLAIPNLGNTSQQEYKVSSVPNTSQSYAKVIKEHGTDFFDKDGVMKDIRAIYQVYNALQEKVQAVCADVEKSERVVESCQAEVNKLRRQITQKK-NEKEQERRLQQALLSRQMPSESLEPAFSPRMPYSGFS-AEGRSTLADAEPSDPPPPYSDFHPNNQESTLSHSRIERSVFMPRPQAVGSSNYASTSAGLKFT-GSGADLLPSQSAAGDSGEETDD-------SDYENLIDPAESPHSEYSHSKNSRPT-THPDEDPRNTQTSQI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TCJ1-1", "uniprot_id": "ABRX2_MOUSE", "id": "Q3TCJ1-1", "name": "BRISC complex subunit Abraxas 2", "aln": "---------MAASISGYTFSAVCFHSANSNADHEGFLLGEVRQEETFSISDSQISNTEFLQVIEIHNHQPCSQLFSFYDYASKVNEESLDRILKDRRKKVIGWYRFRRNTQQQMSYREQVIHKQLTRILGVPDLVFLLFSFISTANNSTHALEYVLFRPNR-RYNQRISLAIPNLGNTSQQEYKVSSVPNTSQSYAKVIKEHGTDFFDKDGVMKDIRAIYQVYNALQEKVQAVCADVEKSERVVESCQAEVNKLRRQITQKK-NEKEQERRLQQALLSRQMPSESLEPAFSPRMSYSGFS-AEGRSTLAETEPSDPPPPYSDFHPNNQESTLSHSRMERSVFMPRPQAVGSSSYASTSGGLKFT-GSGADLLPSQSAAGDSGEESDD-------SDYENLIDPAESPHSEYSHSKNSRPS-THPDEDPRNTQTSQI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15018-1", "uniprot_id": "ABRX2_HUMAN", "id": "Q15018-1", "name": "BRISC complex subunit Abraxas 2", "aln": "---------MAASISGYTFSAVCFHSANSNADHEGFLLGEVRQEETFSISDSQISNTEFLQVIEIHNHQPCSKLFSFYDYASKVNEESLDRILKDRRKKVIGWYRFRRNTQQQMSYREQVLHKQLTRILGVPDLVFLLFSFISTANNSTHALEYVLFRPNR-RYNQRISLAIPNLGNTSQQEYKVSSVPNTSQSYAKVIKEHGTDFFDKDGVMKDIRAIYQVYNALQEKVQAVCADVEKSERVVESCQAEVNKLRRQITQRK-NEKEQERRLQQAVLSRQMPSESLDPAFSPRMPSSGFA-AEGRSTLGDAEASDPPPPYSDFHPNNQESTLSHSRMERSVFMPRPQAVGSSNYASTSAGLKYP-GSGADLPPPQRAAGDSGEDSDD-------SDYENLIDPTEPSNSEYSHSKDSRPM-AHPDEDPRNTQTSQI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AJY3-1", "uniprot_id": "ABRX2_DANRE", "id": "A0A8M3AJY3-1", "name": "BRISC complex subunit abraxas 2", "aln": "---------MAASISGYTFSSVCYHSANSNSDHEGFLLGEVRQEETLNISDSHIGSSEFLSVIEVHNHEPCAQLFSFYDYAGNINEENLDRILKDRRKNVIGWYRFRRNTQQQMSFREQVIHKQLTNILGIPDLVFLLFSFISTANSSTHALEYVLFRPNRNRYNQRISLSIPNLGNTSQQEYKVSSVPNTSKNYASVIKEHGTEFFDKDGVMKDIRAIFQVYSALQERVQAVCGEVDQSERVREKIQEEVNKLKEEIALRKRNSAEEERRIQEAAAETHPDSSTLPESSHSSLTGVVLSGPTAEPSLERPVNSSSPPIYSTALPPDSPS---------AILLPRPQAVGSPGHPSPSLGLGNGDGSSSDSLNRQATGQEDHEEDDDDDEDEDSSEYENLVSEQLQPTSLPDAVALGRPATLWPDGDAHSPPGS--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***********:**:******:***************:.****:*..:***.***:***:**::********.::***.**********:****************:****:*****.:**:***************.************** ********:*********************:.**.*******:**************:***.****:*****.:*::**** *. * *****:.:*: :* *. *:***:*:* . : *.:* : . :. :: . ...:* . *..** ** * :. * ::::********..:.*.* ** **.:* * :. :. *: ** *:****:. . * . .** ** *.:.. * ", "identical_positions": 253, "similar_positions": 93, "identity": "58.03%" }, { "cls_id": "homologset.agr.RGD:1308919", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q4KM95-1", "uniprot_id": "LRC42_RAT", "id": "Q4KM95-1", "name": "Leucine-rich repeat-containing protein 42", "aln": "MAYYLNSEAHLDPGPIYVRENGQLHMVSLALDGVKNSLQKPRPFRLFPKGFSVELCMNREDDTAQKEKTDHFIFTYTREGNLRYSAKSLFSLVLGFISDNVDHIDSLIGFPEQIAEKLFSAAEARQKFTEPGAGLRALQKFTEAYGSLVLCSLCLRNRYLVVAEKLEEIKSFRELTRLDLSCCWLGDEHELLEHLTNEALSSVTQLHLKDNCLSDAGIRKMTAPVRVLKRGLENLTLLDLSCNPEITDAGIGYLFSFRKLNCLDISGTGLKDIKAVKDKLRTHIGLVHSKVPLKEFDHSNCKTEGWADQIVLQWERVSVEAVRQRKDPEPRKAAQYFYQK-RALTEASRKCPLAETHMNSSGKLQFYREKAPDCHEPLL------SQESKKSKKRAFEESEQEQS-SPQSAKQKCVCLAVEDWDLLNSY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R2U7-1", "uniprot_id": "LRC42_MOUSE", "id": "Q8R2U7-1", "name": "Leucine-rich repeat-containing protein 42", "aln": "MAYYLNSEAHLDPGPIYVRENGQLHMVNLALDGVKNSLQKPRPFRLFPKGFSVELCMNREDDTAQKEKTDHFIFTYTREGNLRYSAKSLFSLVLGFISDNVDHIDSLIGFPEQIAEKLFSAAEARQKFTEPGAGLRALQKFTEAYGSLVLCSLCLRNRYLVVAEKLEEIKSFRELTRLDLSCCWLGDEHELLEHLTNEALSSVTQLHLKDNCLSDAGIRKMTAPVRVMKRGLENLALLDLSCNPEITDAGIGYLFSFRKLNCLDISGTGLKDIKAVKDKLRANIGLVHSKVPLKEFDHSNCKTEGWADQIVLQWERVSVEAVRQRKDVEPRKAAQYFYQN-RARTEVTRKCPLAETHMNSSGKLQFYREEAPDCHEPLL------SQESKKSKKRAFKESEQEQS-SPQSAKQKCVCLAVEDWDLLNSY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y546-1", "uniprot_id": "LRC42_HUMAN", "id": "Q9Y546-1", "name": "Leucine-rich repeat-containing protein 42", "aln": "MSYYLSSENHLDPGPIYMRENGQLHMVNLALDGVRSSLQKPRPFRLFPKGFSVELCMNREDDTARKEKTDHFIFTYTREGNLRYSAKSLFSLVLGFISDNVDHIDSLIGFPEQIAEKLFSAAEARQKFTEPGAGLRALQKFTEAYGSLVLCSLCLRNRYLVISEKLEEIKSFRELTCLDLSCCKLGDEHELLEHLTNEALSSVTQLHLKDNCLSDAGVRKMTAPVRVMKRGLENLTLLDLSCNPEITDAGIGYLFSFRKLNCLDISGTGLKDIKTVKHKLQTHIGLVHSKVPLKEFDHSNCKTEGWADQIVLQWERVTAEAVKPRETSEPRAAAQRFYGK-RSRAEAPLKCPLADTHMNSSEKLQFYKEKAPDCHGPVLKHEAISSQESKKSKKRPFEESETEQNNSSQPSKQKYVCLAVEDWDLLNSY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6P5J6-1", "uniprot_id": "LRC42_DANRE", "id": "Q6P5J6-1", "name": "Leucine-rich repeat-containing protein 42", "aln": "--MYLG----EDCGAVYVRENGELRCVS-----AVKTVDPPPQNRLFTRDFTFQLCIDTLPSASRAERRDHFIFTYNKQGSLRYSVKTLFDISLQFIADHVEHVDSLVGFPEQMADKLFSAAEERGKFAELRTASRALQLFCEAYGELVLKSLCLRNRYLLISERLEEIRQFQSLECLDLYGCRLGDNHELFKYITSEALSSLVKLFMGANCLSDAGLQRLTAPVRVMKKGLENLQLLDLSEN-HITEKGLRYLTCFKTLQKLDLSGTKVMMDVSLKGFFR-MMGMALSETPLMDFTHTACKTEGWAEQVINQWEITAAEVPK--KDPKPRTNALRFYGREKFVREMLNSWSETSDATNKDKAVPIHFCKVDDCVQSSPSGE---THSTHKSRKRRLS-TEEEQS---AAPVAKRLPLSVEDLHLLNSY", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **. * *.:*:****:*: *. . .::: * ***.:.*:.:**:: .::: *: *******.::*.****.*:**.: * **:*:*:*:***:*****:*:******* * **:* :. **** * ****.*** *********:::*:****:.*:.* *** * ***:***::::*.*****:.:*.: *******::::******:*:***** ***** * .**: *: ** .*:.*: **:*** : ::* :: :*:. *:.** :* *: *******:*:: *** .:.*. : : :** * ** . : * . . :. *.. : :: :. ** . ::.::**:** :. :* **. .. * : *:*** .*****", "identical_positions": 187, "similar_positions": 128, "identity": "43.59%" }, { "cls_id": "homologset.agr.RGD:1308920", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LY07-1", "uniprot_id": "A0ABK0LY07_RAT", "id": "A0ABK0LY07-1", "name": "Collagen alpha-1(XIX) chain", "aln": "MLMRVERTRATEEGICGHLFPWFQGTMRHTGSWKLWTWVAKFLLPACTCVTVRDKPGTTCPVLRTEGYR---DDR--SILSGFDLGESFALRH-AFCEGDKTCFKLGSTLLIRDTVKIFPKGLPEEYSVAVMFRVRRSTKKERWILWKILNQQNMPQISVVIDGTKKVVEFMFRGAEGDLLNYVFKNRELRPLFDRQWHKLGIGVQPRVLSLYMDCNLIASRHTEERDSVDFHGRTVIAARASDGKPVDIELHQLRIYCNASFLAGESCCNLSPTKCPEQDDFGSTTSSWVTSHTGKTSSYLPGKQEIKDACQCIPNKEEAGN---LGSFGYKGDKGEPGENGLHGTPGLPGQKGEQGLEGIKGDIGEKGEPGAKGDTGLAGLNGQDGLKGDLGPQGPPGPKGEKGDMGPPGPPALTGSIGIQGPQGPPGKEGQRGRRGKTGPPGNPGPPGPPGPPGLQGLQQPFGGYFN---KGTGEHGASGPKGEKGDTGLPGFPGSVGPKGHKGEPGEPLTKGEKGDRGEPGLPGPQGIKGEPGDPGPPGLIGSPGLKGQQGPAGPMGPRGPPGDVGLPGEHGIPGKQGVKGEKGDPGGRLGPPGLPGPKGDAGPPGKSLPGKPGLDGNPGVPGPRGPKGERGLPGIHGSPGDTGPPGVGIPGRTGSQGPAGEPGIQGPRGLPGLP---GMPGNDGAPGKDGKPGLPGPPGDLIALPLLGDIGALMKNFCGNCQANVPGLKSNNGDGGGAGEPGKYDPAARKGDVGPRGPPGVPGREGPKGSKGERGYPGLHGEKGDEGLQGIPGLSGAPGPTGPPGLTGRTGHPGPAGAKGDKGSEGPPGKPGPPGPPGVPLNEGNGMGSLYKIQGGVNVPSYPGPPGPPGPKGDPGPVGEPGEMGLPGLEGFPGVKGDRGPVGPPGVAGISGKPGAPGPPGAPGEPGERGPVGDRGFPGPEGPSGKPGINGQDGLPGAQGIMGKPGDRGPKGERGDQGIPGDRGPQGERGKPGLTGMKGAIGPVGPPGSKGSIGSPGHQGPPG---VPGTPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLSAQSHGRPGPPGKDGLPGPPGDPGPQGYRGQKGERGEPGIGLPGSPGLPGS-SVGLPGSPGAPGPQGPPGPSGRCSPEDCLYPMPPAHQQAGGK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q0VF58-1", "uniprot_id": "COJA1_MOUSE", "id": "Q0VF58-1", "name": "Collagen alpha-1(XIX) chain", "aln": "--------------------------MRHTGSWKLWTWVTTFLLPACTCLTVRDKPETTCPTLRTERYQ---DDRNKSELSGFDLGESFALRH-AFCEGDKTCFKLGSVLLIRDTVKIFPKGLPEEYAIAVMFRVRRSTKKERWFLWKILNQQNMAQISVVIDGTKKVVEFMFRGAEGDLLNYVFKNRELRPLFDRQWHKLGIGVQSRVLSLYMDCNLIASRHTEEKNSVDFQGRTIIAARASDGKPVDIELHQLRIYCNANFLAEESCCNLSPTKCPEQDDFGSTTSSWGTSNTGKMSSYLPGKQELKDTCQCIPNKEEAGLPGTLRSIGHKGDKGEPGEHGLDGTPGLPGQKGEQGLEGIKGEIGEKGEPGAKGDSGLDGLNGQDGLKGDSGPQGPPGPKGDKGDMGPPGPPALTGSIGIQGPQGPPGKEGQRGRRGKTGPPGNPGPPGPPGPPGLQGLQQPFGGYFN---KGTGEHGASGPKGEKGDTGLPGFPGSVGPKGHKGEPGEPLTKGEKGDRGEPGLLGPQGIKGEPGDPGPPGLLGSPGLKGQQGPAGSMGPRGPPGDVGLPGEHGIPGKQGVKGEKGDPGGRLGPPGLPGLKGDAGPPGISLPGKPGLDGNPGSPGPRGPKGERGLPGLHGSPGDTGPPGVGIPGRTGSQGPAGEPGIQGPRGLPGLPGTPGMPGNDGAPGKDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQANVPGLKSIKGDDGSTGEPGKYDPAARKGDVGPRGPPGFPGREGPKGSKGERGYPGIHGEKGDEGLQGIPGLSGAPGPTGPPGLTGRTGHPGPTGAKGDKGSEGPPGKPGPPGPPGVPLNEGNGMSSLYKIQGGVNVPGYPGPPGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGISGKPGAPGPPGVPGEQGERGPIGDTGFPGPEGPSGKPGINGKDGLPGAQGIMGKPGDRGPKGERGDQGIPGDRGPQGERGKPGLTGMKGAIGPVGPAGSKGSTGPPGHQGPPGNPGIPGTPADAVSFEEIKHYINQEVLRIFEERMAVFLSQLKLPAAMLSAQAHGRPGPPGKDGLPGPPGDPGPQGYRGQKGERGEPGIGLPGSPGLPGSSAVGLPGSPGAPGPQGPPGPSGRCNPEDCLYPAPPPHQQAGGK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14993-1", "uniprot_id": "COJA1_HUMAN", "id": "Q14993-1", "name": "Collagen alpha-1(XIX) chain", "aln": "--------------------------MRLTGPWKLWLWMSIFLLPASTSVTVRDKTEESCPILRIEGHQLTYDNINKLEVSGFDLGDSFSLRR-AFCESDKTCFKLGSALLIRDTIKIFPKGLPEEYSVAAMFRVRRNAKKERWFLWQVLNQQNIPQISIVVDGGKKVVEFMFQATEGDVLNYIFRNRELRPLFDRQWHKLGISIQSQVISLYMDCNLIARRQTDEKDTVDFHGRTVIATRASDGKPVDIELHQLKIYCSANLIAQETCCEISDTKCPEQDGFGNIASSWVTAHASKMSSYLPAKQELKDQCQCIPNKGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPGGIIGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQGYRGQKGERGEPGIGLPGSPGLPGTSALGLPGSPGAPGPQGPPGPSGRCNPEDCLYPVSHAHQRTGGN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NA67-1", "uniprot_id": "A0A8M1NA67_DANRE", "id": "A0A8M1NA67-1", "name": "Collagen alpha-1(XVI) chain", "aln": "-------------MFSRGPFSCAKDDMIHYLRWTVFLWIVN-SIPFASGMAVNERIDHTCPPLKLEDKWHT-NVNLHREFTGFDLAEKFLLRKGTVTDSDTPLFRLGSKPLFKPTESVFPNGLSHEYSIVATFRIRKTTKKDRWFVLQIFDKGGTSQVSLIVDGAKKSVEFLALGFLKNSLLYVFKNRDLHALFDRQFHKLGVSVESNAVSIYLDCELIERQVTAERSGIDVSGRTFITTRLEDGKPVDVELQEILVFCDSRIADLDRCCDSPGAMCEPTVTHNPTAIPLVTGYLQKMLSMP--AQLPTDRCHCPALKVL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *.:: *: :* .: ::*.:: :** *: * : .:****.:.* **: :. :.*.. *:*** *:: * .:**:**..**::.. **:*:.:**:**:: ::::: . .*:*:::** ** ***: . : * *:*:**:*:.*****:****:.::...:*:*:**:** : * *:. :*. ***.*::* .******:**::: ::*.: : : **: . : * .. : . *. * * * .* *:* . * ", "identical_positions": 94, "similar_positions": 107, "identity": "8.04%" }, { "cls_id": "homologset.agr.RGD:1308922", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZH78-1", "uniprot_id": "D3ZH78_RAT", "id": "D3ZH78-1", "name": "", "aln": "--MSSSHPEPGAREPQSPRPQPLSQSSSSLLCEGREQRPELRKSVSSTVWRAQQAEASTGPRTLQEEGCQMESTEQAQTANPPSQAAAGGHWRSSTVGNVSTMGIGDLCRLQAPSVAAVQRSHSDLVHSTQTRGHGSVQKPSLSCSALGISPVHRAHLQPGGVAGQGGPTPAPLPSDSSLEDGTSKSACTLGESQVWVPTIELEDTTGLLIGSQGEPQATGQPSTTPCHALPPATLLCTVGEAVPGSTCHALPAKGILAFPKLVASVSESGLQAQCGMKFHCQLSGGISGRAHCCVHPWGPTGLATESGSRTKDVWTMTSATDLALGVAS---AQDAGVQAAPVAACKAVATSPSLEAPKTLNIFPEVMLGPGLEEASSPVREVRWDAEGMTWEVYGASVDPEVLGIAIQKHLEMQFEQLQQAPASE---DSLSTEGRRGPLR----AVMQSLRRPSCCGCSGAAPE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A2I3BRN2-1", "uniprot_id": "A0A2I3BRN2_MOUSE", "id": "A0A2I3BRN2-1", "name": "", "aln": "--MSSSHPEPGAREPQSPRPQALSQSSSSLLCEGREQKPELRKSASSTVWRAQQGEAGSSPRILQEEACQTEIPEHAQTASTASQAGAGGHWRSSTVGNVSTMGIGDLCRLRAPSVAAVQRSHSDLVHSTQTRGHGGVQKPSLSCSALGSSPVHRAQLQPGSVAGQGGQTPAPLQSDSAPEDGTSKSACTLGESQVWVPTVELEDATGLLRGPQGEPKATGQPPTTSCHALPPAALLCTLGEAVAGSCCHALPARGILAFPKLVASVSESGLQAQCGMKFHCKLSGGISGHPHCCVHPWGPTGLATESGSRTKDVWTMTSATDLALGVAS---AQDAGVQAAPAAACKAVATSPSLEAPETLNLFPEVMLESGLRQASSPVRDVRWDAEGMTWEVYGASVDPEVLGIAIQKHLEMQFEQLQQAPASE---DSLSAEGRRGPLR----AVMQSLRRPSCCGCSGAAPE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60269-1", "uniprot_id": "GRIN2_HUMAN", "id": "O60269-1", "name": "G protein-regulated inducer of neurite outgrowth 2", "aln": "--MSSSRPEPGPWAPLSPRLQPLSQSSSSLLGEGREQRPELRKTASSTVWQAQLGEASTRPQAPEEEGNPPESMKPARASGPKARPSAGGHWWSSTVGNVSTMGGSDLCRLRAPSAAAMQRSHSDLVRSTQMRGHSGARKASLSCSALGSSPVHRAQLQPGGTSGQGGQAPAGLERDLAPEDETSNSAWMLGASQLSVPPLDLGDTTAHSSSAQAEPKAAEQLATTTCHALPPAALLCGMREVRAGGCCHALPATGILAFPKLVASVSESGLQAQHGVKIHCRLSGGLPGHSHCCAHLWGPAGLVPEPGSRTKDVWTMTSANDLAPAEASPLSAQDAGVQAAPVAACKAVATSPSLEAPAALHVFPEVTLGSSLEEVPSPVRDVRWDAEGMTWEVYGAAVDLEVLGVAIQKHLEMQFEQLQRAPASE---DSLSVEGRRGPLR----AVMQSLRRPSCCGCSGAAPE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B386-1", "uniprot_id": "A0A8M2B386_DANRE", "id": "A0A8M2B386-1", "name": "", "aln": "MAEAGHTISFPPVGTIPSDPLVTADCCSSELKAEDVLRNSSSEAPTERLNHCQIDQHNASPHRIAETHVS-DSVCLHPMSHQNKHDCSGSLMVHKDLNDHSLLS---IQRSHSDSLQIFKDAAASPRYCEMGASFCQGREKDVCAQSFP-SLVCKQAMPLQQSNTVTTSIRAGSSGSSSPTQPAKHSFIQICEVIPESTCPKFEKPVCCNSHFHHGAVKDTFAAYCHPQPIPAPAQLIPHLVGMDESYKGQGQTGNLLALPRLISSVSETGLDGNR-LLRCCNMDCSWSGP----LRPVGAHQWVDEK--TTSDASTMTSQEDLR----------DVGVQVG----------QDSKELPQHVFPEVCLVQQKTSKSQKSPVREVKWDAEGMTWEVYGASVDPEELGLAIQKHLEIQIKETKGIAAKLSRQNTTTSQHSSGSIQKRKKGFLGSLRHPACCSGTTGAVD", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . . . .. ::..** * : . :: :. : :.* : .: *: * : : : :*. . :.: * :. : * :: * .: : :. . .. :: .:...:: * * : : * . : : :.:* : . .: ... : . . :.:*..: * . : .:**:*:*::****:**:.: : *.:. . .* : *. . * *.*. **** ** *.***.. . * * * : : .. ****:*:*************:** * **:*******:*::: : .*. :: : : *.:: ..: ***:*:**. : .* :", "identical_positions": 85, "similar_positions": 137, "identity": "18.2%" }, { "cls_id": "homologset.agr.RGD:1308923", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4AAA5-1", "uniprot_id": "FAP20_RAT", "id": "D4AAA5-1", "name": "Fanconi anemia core complex-associated protein 20", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEEERRLRGRLSRRRPPAGGGP---PNCRPWFLSEESKSE----PWAALLRSTVGGNTDWTPNSQPLPP---------------------LPAFPSQESLPDPESTVPPEVFTVGSKTFSWTPFPPALRGSGS-----------------------------------------------------------------------------------------------SCRLLRCPEGSPGSPAPSLKGCPALDSRQTPS-----TQECV--QSQLVLLNCPLCQKAFDPKLTQLDVDSHLAQCLAESTEDVVW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UN58-1", "uniprot_id": "FAP20_MOUSE", "id": "Q3UN58-1", "name": "Fanconi anemia core complex-associated protein 20", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEEERRLRGRLSRRRPPAGGGP---PNCRPWFLSEGSKSE----PWAALLRSTVSGTADWTPNRQPLPP---------------------LPAFPSQESLPDPESTVPPEAFTVGSKTFSWTPLPPALRGSGS-----------------------------------------------------------------------------------------------SRHLFCEPEGSLGSPTPSLKGCPALNSGRTPS-----AQECVPVQSPLALLSCPLCQKAFDPKLTQLDVDSHLAQCLAECTEDVVW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6NZ36-1", "uniprot_id": "FAP20_HUMAN", "id": "Q6NZ36-1", "name": "Fanconi anemia core complex-associated protein 20", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEAARRPRLGLSRRRPRPAGGP---SGGRPWFLLGGDERER---LWAELLR-TVS--PELILD-HEVPS---------------------LPAFPGQEPRCGPE---PTEVFTVGPKTFSWTPFPPDLWGPGR-----------------------------------------------------------------------------------------------SYRLLHGAGGHLESPARSLPQRPAPDPCRAPR-----VEQQPSVEGAAALRSCPMCQKEFAPRLTQLDVDSHLAQCLAESTEDVTW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7UUX0-1", "uniprot_id": "A0A8N7UUX0_DANRE", "id": "A0A8N7UUX0-1", "name": "", "aln": "MQCVYNRMTVMSKLKRKKLSVEDYKSEQQTLIKKLNDSRCSVALQDSSCATTSTGRERWWESSELSDAERLWALTLTALCPNLQSDDLEESIPQLPPPSSTKSPVQTVSDWRWCNGNKDVNPPPGLPAPSFLVHPPPANDPKNPSQPPAEENTRASDPPSLSDQEKHASSPDGDSVPVCSTQTTQQRKLDDGVNCLEDCKLLDDQGDRFGQARNVSETRRSQAESRTVRSVEGKSAEMGAGKSESGIRTFSGAEGPALVLETKQEASGSGSGQEAKTGAGQRAKSGVREFGLGTGTKSGIAKGAKSGLGRNSIASGSGLDLGTKSGASRSGLVLGTKSGASGSGLVLGTKSGASGSGLVLGTKSGASGSGLVLGAKSGSGQEAKSGLVRSGSGLVQSGTVQEEENGLMVFRSGLGTNARASGSKLGMETKSGTEWEAKSGIRGSGTNSVEEKIANSGSSESGLGLETKSGTEQEAKSGTRESGTNSGEEKLAKSGLGRSGANSGASRSGSGLETTRSPEGSESGLETKSGAEHRSELECCPMCLMPFPAGFTQMECDGHLAQCLSEMHDDIIW", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* :. * :.. ...* .. * : * : : * * ::. . . : .. .. ... ..: . . :.:*.*: * . * .* . :* * : : : .. :. ::* : : * **:* * . :**:: *.******:* :*: *", "identical_positions": 32, "similar_positions": 61, "identity": "5.58%" }, { "cls_id": "homologset.agr.RGD:1308924", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "O14907-1", "uniprot_id": "TX1B3_HUMAN", "id": "O14907-1", "name": "Tax1-binding protein 3", "aln": "-----MSYIPGQPVTAVVQRVEIHKLRQGEN-----LILGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPAEIAGLQIGDKIMQVNGWDMTMVTHDQARKRLTKRSEEVVRLLVTRQSLQKAVQQSMLS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q4QQV1-1", "uniprot_id": "TX1B3_RAT", "id": "Q4QQV1-1", "name": "Tax1-binding protein 3", "aln": "-----MSYIPGQPVTAVVQRVEIHKLRQGEN-----LILGFSIGGGIDQDPSQNPFSEDKTDK--------------------------VNGWDMTMVTHDQARKRLTKRSEEVVRLLVTRQSLQKAVQQSMLS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DBG9-1", "uniprot_id": "TX1B3_MOUSE", "id": "Q9DBG9-1", "name": "Tax1-binding protein 3", "aln": "-----MSYTPGQPVTAVVQRVEIHKLRQGEN-----LILGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPAEIAGLQIGDKIMQVNGWDMTMVTHDQARKRLTKRSEEVVRLLVTRQSLQKAVQQSMLS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9W0P4-1", "uniprot_id": "Q9W0P4_DROME", "id": "Q9W0P4-1", "name": "PDZ domain-containing protein", "aln": "MAKMAFQHQAGTAMECLSIPITLHKEKDYDQEGREILKCGFKIGGGIDQDYKKSPQG--YTDYGIYVTEVHEGSPAARAGLRIHDKILQCNGYDFTMVTHKKAVSYIRKNP--ILNMLVARKGVTST-------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.: .* .: .: : :** :: :: * **.******** .:.* . ** **:*:*****.:* . : *.. ::.:**:*:.: .: ", "identical_positions": 30, "similar_positions": 37, "identity": "22.39%" }, { "cls_id": "homologset.agr.RGD:1308925", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZWU1-1", "uniprot_id": "D3ZWU1_RAT", "id": "D3ZWU1-1", "name": "", "aln": "MSTTTAAAPTGIPAVPGPVN--PPPPEVSNPSKPGRKTNQLQYMQNVVVKTLWKHQFAWPFYQPVDAIKLNLPDYHKIIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKIFLQKVAQMPQEEVELLPPAPKG---KGRKPA--------AGAQNAGAQQMGAVSSVSPA---------------------------PPFQNIPPTVSQTPVIAATPVPTITANVTSVPVPPPAAPPPPATP--IVP--------------------------------------------------------------------------------------------------------------------VVPPTPPVVKKKGVKRKADTTTPTTSAITASRSESPPPLSEPKQ-----AKVVARRESG----------------GRPIKPPKKDLEDGEVP--QHAGKKGKLSEHLRHCDSILREMLSKKHAAYAWPFYKPVDAEALELHDYHDIIKHPMDLSTVKRKMDSREYPDAQGFAADIRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPMEVPALPAPTAP-------------------------IVSKGAESSRSSEESSSDSGSSDSEEERATRLAELQEQLKAVHEQLAALSQAPVNKPKKKKEKKEKEK-------------------------------------------------------------------------------------------------------------------------------------------------------KKKDKE--KEKEKHKAKSEEEKKAKAAPAAKQ----------------AQQKKAPTKKANSTTTASRQLKKGGKQASAS-----------------YDSEEEEEGLPMSYDEKRQLSLDINRLPGEKLGRVVHIIQSREPSLRDSNPDEIEIDFETLKPTTLRELERYVKSCLQKKQRKPLSTSGKKQAAKSKEELAQEKKKELEKRLQDVSGQLNS-KKPTKK-EKSGS--APSGGPSRLS-SSSSSESASSSSS-GSSSDSSDSE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K2F0-1", "uniprot_id": "BRD3_MOUSE", "id": "Q8K2F0-1", "name": "Bromodomain-containing protein 3", "aln": "-MSTTAAAPTGIPAVPGPVN--PPPPEVSNPSKPGRKTNQLQYMQNVVVKTLWKHQFAWPFYQPVDAIKLNLPDYHKIIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKIFLQKVAQMPQEEVELLPPAPKG---KGRKPA--------AGAQNAGSQQVAAVSSVSPA---------------------------TPFQNIPPTVSQTPVIAATPVPTITANVTSVPVPPPAAPPPPATP--IVP--------------------------------------------------------------------------------------------------------------------VVPPTPPVVKKKGVKRKADTTTPTTSAITASRSESPPPLSEPKQ-----AKVVARRESG----------------GRPIKPPKKDLEDGEVP--QHAGKKGKLSEHLRHCDSILREMLSKKHAAYAWPFYKPVDAEALELHDYHDIIKHPMDLSTVKRKMDSREYPDAQGFAADIRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPMEAPALPAPTAP-------------------------IVSKGAESSRSSEESSSDSGSSDSEEERATRLAELQEQLKAVHEQLAALSQAPVNKPKKKKEKKEKEK-------------------------------------------------------------------------------------------------------------------------------------------------------KKKDKDKDKEKEKHKAKSEEEKKAKAAPAAKQ----------------AQQKKAPTKKANSTTTASRQLKKGGKQASAS-----------------YDSEEEEEGLPMSYDEKRQLSLDINRLPGEKLGRVVHIIQSREPSLRDSNPDEIEIDFETLKPTTLRELERYVKSCLQKKQRKPLSTSGKKQAAKSKEELAQEKKKELEKRLQDVSGQLNS-KKPTKK-EKSGS--APSGGPSRLS-SSSSSESASSSSS-GSSSDSSDSE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15059-1", "uniprot_id": "BRD3_HUMAN", "id": "Q15059-1", "name": "Bromodomain-containing protein 3", "aln": "MSTATTVAPAGIPATPGPVN--PPPPEVSNPSKPGRKTNQLQYMQNVVVKTLWKHQFAWPFYQPVDAIKLNLPDYHKIIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKIFLQKVAQMPQEEVELLPPAPKG---KGRKPA--------AGAQSAGTQQVAAVSSVSPA---------------------------TPFQSVPPTVSQTPVIAATPVPTITANVTSVPVPPAAAPPPPATP--IVP--------------------------------------------------------------------------------------------------------------------VVPPTPPVVKKKGVKRKADTTTPTTSAITASRSESPPPLSDPKQ-----AKVVARRESG----------------GRPIKPPKKDLEDGEVP--QHAGKKGKLSEHLRYCDSILREMLSKKHAAYAWPFYKPVDAEALELHDYHDIIKHPMDLSTVKRKMDGREYPDAQGFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPVEAPALPAPAAP-------------------------MVSKGAESSRSSEESSSDSGSSDSEEERATRLAELQEQLKAVHEQLAALSQAPVNKPKKKKEKKEKEK-------------------------------------------------------------------------------------------------------------------------------------------------------KKKDKE--KEKEKHKVKAEEEKKAKVAPPAKQ----------------AQQKKAPAKKANSTTTAGRQLKKGGKQASAS-----------------YDSEEEEEGLPMSYDEKRQLSLDINRLPGEKLGRVVHIIQSREPSLRDSNPDEIEIDFETLKPTTLRELERYVKSCLQKKQRKPFSASGKKQAAKSKEELAQEKKKELEKRLQDVSGQLSSSKKPARK-EKPGS--APSGGPSRLS-SSSSSESGSSSSS-GSSSDSSDSE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TUX3-1", "uniprot_id": "A0AB32TUX3_DANRE", "id": "A0AB32TUX3-1", "name": "", "aln": "--MSAVTSPAQVPAP--IVN--PPPPEFINSGKPGRKTNQLQYMQNVVVKTLWKHQFAWPFYTPVDAIKLNLPDYHKVIKNPMDMGTIKKRLENNYYWTAGECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKIFLQKVAQMPQEEVELLPPPPKG---KARKPG--------APPGSE-NQQSIALTPGSPS---------------------------SSCPSSPPQLAQTPVIAATPVATITTNVQAA---------PPATA--MIP--------------------------------------------------------------------------------------------------------------------TAQP----VVKKGVKRKADTTTPTTCAITASRSESPTAMLESKH-----SKVISRREST----------------GRPIKPPKKDLEDGDVQ--QPGNKKSKLNDHLKYCDTILKEMLSKKHAAYAWPFYKPVDAEALELHDYHEIIKQPMDLSTVKKKMDSREYPDAQNFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMKFAKMPDEPAEPSSPNAVSATA------------------------VVSKSTGSSESSADSSSSS--SDSEEERATRLAELQEQLKAVHEQLAALSQGPVSKPKKKKEKKEKEK-------------------------------------------------------------------------------------------------------------------------------------------------------KKKDKE--KDKDKNKVKAEEDKKAKSTQPNKQ----------------TPQKKTSARKPNSTSTT-RQAKKGGKPGAAN-----------------YESDEEE-SLPMSYDEKRQLSLDINRLPGEKLGRVVHIIQSREPSLRDSNPDEIEIDFETLKPSTLRELERYVKSCLQKKQRKPLPGTGKK-SAKSKEELVQEKKKELEKRLQDVSGQLNNNKKPPKKAEKAGS--AQGGGASRLSGSSSSSDSGSSSSS-GSSSESSDSD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P13709-1", "uniprot_id": "FSH_DROME", "id": "P13709-1", "name": "Homeotic protein female sterile", "aln": "--MSSSEPPPRYEPPVEPVNGIVQPPVIPPAERPGRNTNQLQYLIKTVMKVIWKHHFSWPFQQPVDAKKLNLPDYHKIIKQPMDMGTIKKRLENNYYWSAKETIQDFNTMFNNCYVYNKPGEDVVVMAQTLEKVFLQKIESMPKEELELEPVTAKGGKKKQRAPATPKSSSGGAGASTGSGTSSAAVTSGPGSGSTKVSVAASSAQQSGLQGATGAGGGSSSTPGTQPGSGAGGAIAARPVSAMGGTVSSTAGGAPSIPPISTMPPHTVPGSTNTTTTAMAGGVGGPGAAGANPNAAALMASLLNAGQTGAYPGAPGQTAVNSSSLLDGSTAAVAAAAAAAAAAAAAAGGAAGAAGGAGTIPAVAVNAANAVQAYVNAGVSVGVDAVIPPQQPAKIKKGVKRKADTTTP-----TANAFESPYTQMDSKS-----AKIATRRESNRQDLTFQGSGYNMSPLGVSGVPGLGGLVAGGVAGVAVAKNKEKLSDALKSCNEILKELFSKKHSGYAWPFYKPVDAEMLGLHDYHDIIKKPMDLGTVKRKMDNREYKSAPEFAADVRLIFTNCYKYNPPDHDVVAMGRKLQDVFEMRYANIPDEPVANAAHHHGHGHGHGHGHGHGHGHGHGHGHGHGYGGSSSLKHDASDSSSEDSSDTENESNSDEERSARLKMLESKLLGLQEEIRKLSEEASAKKKAKKKLKEKKKSIGGGSGSGSASHHCHATGGGANAGGAGGPGSGGHGSVSVPGGVGSLGPGGAGGANLNALLGGSLVGHGGAAVAGGVPNVGALHSQVHDVAMAFSQMAGGGAAAGAGFGAGVTAAGASSGGKAGTLAGALAAGAAAGAGGTTAGSGSSKGAKSKGGRGAKGSGAGGVGASNNAAAGNAAGGAAGAAAGAGSVGGVGGAGAAGGGNASKRAKGSSSAGAGGGVGGANASAGGAGARGSSKKKPSQVMNFDSEEEDTAKPMSYDEKRQLSLDINKLPGDKLGRVVHIIQNREPSLRDSNPDEIEIDFETLKPSTLRELESYVASCLRKKTHK-------KPSGKSKDEQMAEKKQELEKRLQDVTGQLGASKKTAKKDESASSKVEAVQPANPVSSSSSSSDSSSSSSSDSSSSDSSDSEAGDGDERPPRKKKSRDSNGSNVNNPSINVVMGGNLPSGALSPTTMLMGLDHVVNSNTPTSQMSNMLGNANPLTAAAMLNNNNKTSLPGSNFGGAPAPGNMMHAGAGVPVAGAAVSASTGQQHNKNGPNDLSKVQPGGPINAALPPHSFAGGTATVATSQSSGGIRIASNLHKPSGLGGGDLGEHHAALAAALTSGINSTGTAGGGINNNGGSNNNANPLGGSHGDAMVNASLASLASGLKQIPQFDDPVEQSLASLEFSAGSTGKSGLTDNFLMQQHLMQPAGPQQQQQQQQQQPFGHQQQQQQQQQQQQQQQQHMDYVTELLSKGAENVGGMNGNHLLNFNLDMAAAYQQKHPQQQQQQAHNNGFNVADFGMAGFDGLNMTAASFLDLEPSLQQQQMQQMQLQQQHHQQQQQQTHQQQQQHQQQHHQQQQQQQLTQQQLQQQQQQQQQQQHLQQQQHQQQHHQAANKLLIIPKPIESMMPSPPDKQQLQQHQKVLPPQQSPSDMKLHPNAAAAAAVASAQAKLVQTFKANEQNLKNASSWSSLASANSPQSHTSSSSSSSKAKPAMDSFQQFRNKAKERDRLKLLEAAEKEKKNQKEAAEKEQQRKHHKSSSSSLTSAAVAQAAAIAAATAAAAVTLGAAAAAALASSASNPSGGSSSGGAGSTSQQAITGDRDRDRDRERERERSGSGGGQSGNGNNSSNSANSNGPGSAGSGGSGGGGGSGPASAGGPNSGGGGTANSNSGGGGGGGGPALLNAGSNSNSGVGSGGAASSNSNSSVGGIVGSGGPGSNSQGSSGGGGGGPASGGGMGSGAIDYGQQVAVLTQVAANAQAQHVAAAVAAQAILAASPLGAMESGRKSVHDAQPQISRVEDIKASPGGQGQSSPAQQSPQDRAAAKRAEQRRAEQERRRREALAGQIDMNMQSDLMAAFEETL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P35817-1", "uniprot_id": "BDF1_YEAST", "id": "P35817-1", "name": "Bromodomain-containing factor 1", "aln": "-MTDITPVQNDVDVNGNNVN-DDVSSNLKRPIDQGDPSNGLAEEENPANNQLHLKKARLDGDALTSSPAG-------LAENGIEGATLAANGENGYNATGSGAEDEQQGLKK------EEGGQGTKQEDLDENSKQELPMEVPKEPAPAPPPEPDMNNLPQNPIP--------KHQQKHALLAIKAVKRLKDAR-----------------------PFLQPVDPVKLDIPFYFNYIKRPMDLSTIERKLNVGAYEVPEQITEDFNLMVNN-------------------------------------------------------------------------------------------------------------------SIKFNGPNAGISQMARNIQASFEKHMLNMPAKDAPPVIAKGRRSSAQEDAPIVIRRAQTHN--------------GRPKRTIHPPKSKDIYPYESKKPKSKRLQQAMKFCQSVLKELMAKKHASYNYPFLEPVDPVSMNLPTYFDYVKEPMDLGTIAKKLNDWQYQTMEDFERDVRLVFKNCYTFNPDGTIVNMMGHRLEEVFNSKWADRPNLDDYDSDEDSRTQG---------------------------------DYDDYESEYSESDIDETIITNPAIQYLEEQLARMKVELQQLKKQELEKIRKERRLARGSK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KRGKRSKGRSGSKNASSKGRRD------------------------KKNKLKTVVTYDMKRIITERINDLPTSKLERAIDIIKKSMPNISED--DEVELDLDTLDNHTILTLYNTFFRQYESSSGASNGLDGTSGVTRDASSLSPTSAGSRKRRSKALS-----QEEQSRQIEKIKNKLAILDSASPLSQNGSPGQIQSAAHNGFSSSSDDDVSSESEEE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** .. . . * :* * : . : : :: ..: : :: :: .*: . **.* :. :: : : . : : . : *: : .:*:* * .. . . *:. : . *: . : . : *: ::: . .* : : : ** . * . . . :. :*.: :: *: :*:*:::***:.* :** :***. : * *.: :*.****.*: :*::. :* * *:**:*.***.:** . * *.::*::**: ::*. *: . . .. :*. . :. . : *:.:* :: :: *.: * : ::. . .* ::.:. : : * .::. ::** ** :: ** ** .** *.:.**:. *.: :. **:*:*::**. *: * . ... . :. .. . . ::* : :: :: .:: *. . .. :* ..*..: *:: . ***...* . ", "identical_positions": 98, "similar_positions": 206, "identity": "4.76%" }, { "cls_id": "homologset.agr.RGD:1308926", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZQF4-1", "uniprot_id": "FKBP6_RAT", "id": "D3ZQF4-1", "name": "Inactive peptidyl-prolyl cis-trans isomerase FKBP6", "aln": "----------------MSVFSRLRNGIPPSRDDCQSPYERLS----------QRMLDISG---------------------DRGVLKDIIREG--AGDPVTPDASVLVKYSGYLEHMDKPFDSNCFRKTPRLMKLGEDITLWGMELGLLSMRRGELARFLFKPTYAYGTLGCPPLIPPNATVLFEIELIDFLDSAESDKFCALSAEQQEQFPLQKVLKVAATEREFGNYLFRQNRFCDAKVRYKRALLLLHRRLAICEEQHLVEPAELLVLLN-LSFVYLKLDRP--AMALRYGEQALLIDKRNAKALFRCGQACLLLTEYEQARDFLVRAQKEQPCNHDINNELKKLSSHYRDYVDREREMCHRMFAPCGSGSSVGGN------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91XW8-1", "uniprot_id": "FKBP6_MOUSE", "id": "Q91XW8-1", "name": "Inactive peptidyl-prolyl cis-trans isomerase FKBP6", "aln": "----------------MGGSTRDPGALEGAGILGQSPYERLS----------QRMLDISG---------------------DRGVLKDIIREG--TGDTVTPDASVLVKYSGYLEHMDKPFDSNCFRKTPRLMKLGEDITLWGMELGLLSMRKGELARFLFKPAYAYGTLGCPPLIPPNATVLFEIELIDFLDSAESDKFCALSAEQQEQFPLQKVLKVAATEREFGNYLFRQNRFCDAKVRYKRALLLLHRRLATCEEQHLVEPAVLLVLLN-LSFVYLKLDRP--AMALRYGEQALLIDKRNAKALFRCGQACLLLTEYERARDFLVRAQKEQPCNHDINNELKKLSSHYRDYVDREREMCHRMFAPCGSRSSVGGN------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75344-1", "uniprot_id": "FKBP6_HUMAN", "id": "O75344-1", "name": "Inactive peptidyl-prolyl cis-trans isomerase FKBP6", "aln": "----------------MGGSALNQGVLEGDDAPGQSLYERLS----------QRMLDISG---------------------DRGVLKDVIREG--AGDLVAPDASVLVKYSGYLEHMDRPFDSNYFRKTPRLMKLGEDITLWGMELGLLSMRRGELARFLFKPNYAYGTLGCPPLIPPNTTVLFEIELLDFLDCAESDKFCALSAEQQDQFPLQKVLKVAATEREFGNYLFRQNRFYDAKVRYKRALLLLRRRSAPPEEQHLVEAAKLPVLLN-LSFTYLKLDRP--TIALCYGEQALIIDQKNAKALFRCGQACLLLTEYQKARDFLVRAQKEQPFNHDINNELKKLASCYRDYVDKEKEMWHRMFAPCGDGSTAGES------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W1I9-1", "uniprot_id": "FKBP6_DROME", "id": "Q9W1I9-1", "name": "Inactive peptidyl-prolyl cis-trans isomerase shutdown", "aln": "MEENFEPYTPQLLKNPLSYSDLVKKGVEFEVDNSQQNHARDLGLDSDSDSDYEDALDVDGEELRSPWTYSFDELRALMSEIDENIYKRITRTGHVDREAVPNKARVSVRYSGYWEGETAPFDSSLLRGSKFVFETGQGTVVEGLEVAVRSMRPYEQAEFIISYKLLFGELGCPPRIKPKADALFKVEVIDYSLIGDAKGIDAIPQEDRDKF--CVVYPKAVDLHLHGKDSVKLGRYQSAATAFERAVSSLNYCRMANDEEERKQTELLTTLNQNLMIVYNKMNKPKRACIMMKALRHLTMGNPSCKALFQEGRALAALGEYNLARNAYLQAQAKQPANKEISDEIISMNKRISKYEEASRDIWARAFSLKNSKSDVRKTPAQLEKEAKEQDFNDKMEDLIRRFKNTSDQQVSFSRKSYSNAQFDATCKLAKEHNLKLTLSPIQEDVLTLSKPDVKFA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. : *. : * : **:.* *..: * : * * : *. .* * *:**** * ****. :* : ::: *:. .: *:*:.: *** * *.*::. :* ***** * *:: .**::*::*: .::. : *:. *::::* * *. : .*: .: .*: .* . ::**: *. :*:. :. * .* : * :.* *:::* : : . : * :.: ..****: *:* * **: **: ::** :** *::*.:*: .: . .* : .::: * *: .. * . . ", "identical_positions": 85, "similar_positions": 115, "identity": "18.6%" }, { "cls_id": "homologset.agr.RGD:1308927", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZPN1-1", "uniprot_id": "D3ZPN1_RAT", "id": "D3ZPN1-1", "name": "", "aln": "--------------------------MGSS-------CRIECIFFSEFHPTLGPKITYQVPEDFIS--RELFDTVQVYIITKPELQNKLITVTAMEKKLIGCPVCIEHK-KYSRNALLFNLGFVCDAQAKTCALEPIVKKLAGYLTTLELESSFVSTEE---------------------------------------------------------------SKQKLVPIMTILLEELNASGRCTLPIDESNTIHLKVIEQR-PDPPVAQEYDVPVFTKDKEDFFSSQWDLTTQQILPYIDGFRHVQKISAEADVELNLVRIAIQNLLYYGVVTLVSILQYSNVYCPTPKVQDLVDDKSLQEACLSYVTKQGHKR---------------------------------------------------------------------------------------ASLRDVFQLYCSLSPGTTVRDLIG--RHPQQLQHVDERKLIQFGLMKNLIRRLQKYPVRVSREERSHP----------------------------------------------------------------------------ARLYTGCHSYDEICCKTGMSYHELDERLENDPNIIICWK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WUE4-1", "uniprot_id": "NPRL2_MOUSE", "id": "Q9WUE4-1", "name": "GATOR1 complex protein NPRL2", "aln": "--------------------------MGSS-------CRIECIFFSEFHPTLGPKITYQVPEDFIS--RELFDTVQVYIITKPELQNKLITVTAMEKKLIGCPVCIEHK-KYSRNALLFNLGFVCDAQAKTCALEPIVKKLAGYLTTLELESSFVSNEE---------------------------------------------------------------SKQKLVPIMTILLEELNASGRCTLPIDESNTIHLKVIEQR-PDPPVAQEYDVPVFTKDKEDFFSSQWDLTTQQILPYIDGFRHVQKISAEADVELNLVRIAIQNLLYYGVVTLVSILQYSNVYCPTPKVQDLVDDKSLQEACLSYVTKQGHKR---------------------------------------------------------------------------------------ASLRDVFQLYCSLSPGTTVRDLIG--RHPQQLQHVDERKLIQFGLMKNLIRRLQKYPVRVSREERSHP----------------------------------------------------------------------------ARLYTGCHSYDEICCKTGMSYHELDERLENDPNIIICWK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WTW4-1", "uniprot_id": "NPRL2_HUMAN", "id": "Q8WTW4-1", "name": "GATOR1 complex protein NPRL2", "aln": "--------------------------MGSG-------CRIECIFFSEFHPTLGPKITYQVPEDFIS--RELFDTVQVYIITKPELQNKLITVTAMEKKLIGCPVCIEHK-KYSRNALLFNLGFVCDAQAKTCALEPIVKKLAGYLTTLELESSFVSMEE---------------------------------------------------------------SKQKLVPIMTILLEELNASGRCTLPIDESNTIHLKVIEQR-PDPPVAQEYDVPVFTKDKEDFFNSQWDLTTQQILPYIDGFRHIQKISAEADVELNLVRIAIQNLLYYGVVTLVSILQYSNVYCPTPKVQDLVDDKSLQEACLSYVTKQGHKR---------------------------------------------------------------------------------------ASLRDVFQLYCSLSPGTTVRDLIG--RHPQQLQHVDERKLIQFGLMKNLIRRLQKYPVRVTREEQSHP----------------------------------------------------------------------------ARLYTGCHSYDEICCKTGMSYHELDERLENDPNIIICWK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VXA0-1", "uniprot_id": "NPRL2_DROME", "id": "Q9VXA0-1", "name": "GATOR complex protein NPRL2", "aln": "MHSHTNETAATSTTAGAVTNGAGGSGAGAAGAHGSTEGKIRCIFLSEFHATAGCKISCQVPDNYIS--KDVFDAINVYIIPKQHLQRCILTVNAMDVKIVGYPVGIQDQQKYARNAFLFNLCFVCDSRARSVQYEPVVKKLSEYLIMMEEESCFLSRED---------------------------------------------------------------DKRRLQNIFETVLRDLNER-KVATIVEGDNTIYLKIVMHK-PDPPPVKDHMVPLLLANLRDAPLDNWDLTTQQILPYINGINHVARIAAEADVETDLVKSCIQNLVYYGVVQLLPILKYSNVYM-TQNLKHLIQSASLSGACRKYVALRPDKTL--------------------------------------------------------------------------------------PSVQRIFQFYASMTHGVTLRAICQ--RLCPQHHNIDERRMVIFGLQHRFIRCIHKYPVFTG-SVPSGR----------------------------------------------------------------------------QKMYTGLISFDEICCKTGLSPCTIERDIEKDTNVTVIWK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39923-1", "uniprot_id": "NPR2_YEAST", "id": "P39923-1", "name": "Nitrogen permease regulator 2", "aln": "---------------------MLSYFQGFVP--------IHTIFYSVFHPTEGSKIKYEFPPNNLKNHGINFNTFKNYIIPKPILCHKLITFKYGTYRIVCYPVTINSP-IYARNFFSFNFVFVFPYDCETSPYEPAITRLGKMFKVLEEQNQLLSKSERDPVFFDLKVLENSTTTPSTAGPSSTPNPSSNTTPTHPTSEKDTKDMRSSRYSDLIKDLGLPQSAFSIQDLLMRIFQDLNNYSECLIPIDEGNAVDIKIFPLLRPPTTCVSLEDVPLSSVNLKKIIDVNWDPTMMSIVPYIDGLNSIAKISKLSNSDPGLVIECIRHLIYYKCVTLSDIFQFSNIYAPSSLIRNFLTDPLMASDCQSYVTFPEVSKISNLPLNKSLGSGDQDSPSFSVRRKSKSSSIPSNPDSRTTSFSSTSRVSQNSSLNSSFSSIYKDWRQSQTSCSSSNIHVINNRNRFLPTRSCLFDLYRSLSQGQTLKTWYESKYMILKENNIDIRRFITFGLEKRIIYRCYSFPVMINAGSREPKEMTPIITKDLVNNDKLLEKRNHNHLLSATGSRNTAQSGNLKPERPSKVSFEMQRVSSLATGKSTMPKLSDEEEGILEESIRNAETFDKICVLLSKPKLEVESYLNELGEFKVINS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *. ** * **.* * **. :.* : :. *::.: ***.* * . ::*.. ::: ** *: *:** : **: ** ..: ** :.:*. : :* :. ::* .: . : :: ::.:** . :: .*:: :*:. * .. .. **: : .. :** * .*:***:*:. : :*: :: : .** .*::*:** * * *:::**:* : ::.:: . : * .**: . .: :*::* *:: * *:: : :::* *::: *** :.:* .:** . . . ::*:** . . :: ::: :. : .", "identical_positions": 81, "similar_positions": 135, "identity": "12.56%" }, { "cls_id": "homologset.agr.RGD:1308928", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R3C6-1", "uniprot_id": "RBM19_MOUSE", "id": "Q8R3C6-1", "name": "Probable RNA-binding protein 19", "aln": "MSRLIVKNLPNGMKEERFRQLFAAFG---------------TLTDCSLKFTKDGKFRKFGFIGFKSEEEAQAALNHFHRSFIDTTRITVEFCKSFGDPSKPRAWSKHAQKS--------SQPKQPSQDSVPSDTKKDK-KKK-GPSDLEKLKEDAKFQEFLSIHQKRTQVATWANDALEAKLP----------KAKTKASSDYLNFDSDSNSDSGQESEEEPAREDPEEEQGLQPKAAVQKELSDMDYLKSKMVRAEVSSEDEDEEDSEDEAVNCEEGSEEEEEEGSPASPAKQ-----GGVSRGAVPGVLRPQEAAG------------------------------------------------------KVEKPVSQKEPTTPYTVKLRGAPFNVTEKNVIEFLAPLKPVAIRIVRNAHGNKTGYVFVDLSSEEEVKKALKCNRDYMGGR--YIEVFREKQ--APTAR-GPPKS-TTPWQGRTLGENEE-----EEDLADSGRLFVRNLSYTSSEEDLEKLFSAYGPLSELHYPIDSLTKKPKGFAFVTFMFPEHAVKAYAEVDGQVFQGRMLHVLPST-IKKEAS-QEANAPGSS-YKKKKEAMDKANSSSSHNWNTLFMGPNAVADAIAQKYNATKSQVFDHETRGS-VAVRVALGETQLVQEVRSFLIDNGVCLDSFSQAA--AERSKTVILAKNLPAGTLAAEIQETFSRFGSLGRVLLPEGGITAIVEFLEPLEARKAFRHLAYSKFHHVPLYLEWAPIGVFG-AAPQKKDSQ--HEQPAEKAEVEQETVLD---PEGEKASVEGAEASTGKMEEEEEEEEEEEEE-SIPGCTLFIKNLNFSTTEETLKGVFSKVGAIKSCTISKKKNKAG--VLLSMGFGFVEYKKPEQAQKALKQLQGHTVDGHKLEVRISERATKP-ALTST-RKKQVPKKQTTSKILVRNIPFQANQREIRELFSTFGELKTVRLPKK-MTGTGAHRGFGFVDFITKQDAKKAFNALCHSTHLYGRRLVLEWADSEVT--VQTLRRKTARHFQ---EPPKKKR-SAVLDGILEQLEDEDNSDGEQALQL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LLW4-1", "uniprot_id": "A0ABK0LLW4_RAT", "id": "A0ABK0LLW4-1", "name": "Probable RNA-binding protein 19", "aln": "MSRLIVKNLPNGMKEDRFRQLFAAFG---------------TLTDCSLKFTKEGKFRKFGFIGFKSEEEAQAALNHFHRSFIDTSRITVEFCKSFGDPSKPRAWSKHAQKP--------SQPKQPSQDSIPSDTKKDK-KKKKVPSDLEKLKEDAEFQEFLSIHQKRTQVATWANDALEAELP----------KAKAKPSSDYLNFDSDSNSDSGQESEEEPAGEDGEEEQGLQPKAAVQKELSDMDYLKSKMVRAEVSSEDEDKEDSEDEAVNCEEGSEAEEEEGSPTCPAQQ-----AGVNRGAVLGSLRPQEAAGKALRTAASYSSLRAQLNSQQGFSWISPAPLPAPGVPATTCHTSKRQAFTIFVISQVEKPASQKEPTTPYTVKLRGAPFNVTEKNVLEFLAPLKPVAIRIVRNAHGNKTGYVFVDLSSEEEVKKALKCNREYMGGR--YIEVFREKQ--ASAAR-GAPKSSSAPWQGRTLGEHEE-----EEDLADSGRLFVRNLSYTSSEEDLEKLFSAYGPLSELHYPIDSLTKKPKGFAFVTFMFPEHAVKAYAEVDGQVFQGRMLHVLPST-IKKEAN-QEANAPGSS-YKKKKEAMDKANSSSSHNWNTLFMGPNAVADAIAQKYNATKSQVFDHETKGS-VAVRMALGETQLVQEVRSFLIDNGVCLDSFSQAA--AERSKTVILAKNLPAGTLAAELQEIFSRFGSLGRVLLPEGGITAIVEFLEPLEARKAFRHLAYSKFHHVPLYLEWAPIGVFG-AAPQKKDSQ--PEQPAQKAEAEQETVLN---PEGEKALVEGAEASMGKMEEEEEEEEEEEEEESIPGCTLFIKNLNFNTTEETLKEVFSRVGAVKSCTISKKKSKAG--VLLSMGFGFVEYKKPEQAQKALKRLQGHIVDGHKLEVRISERATKP-ALTST-RKKQVPKKQTTSKILVRNIPFQANQREIRELFSTFGELKTVRLPKK-MTGTGAHRGFGFVDFITKQDAKKAFNALCHSTHLYGRRLVLEWADSEVT--VQALRRKTAKHFQ---EPPKKKR-SAVLDGILEQLEDGDDSDSEETLQL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y4C8-1", "uniprot_id": "RBM19_HUMAN", "id": "Q9Y4C8-1", "name": "Probable RNA-binding protein 19", "aln": "MSRLIVKNLPNGMKEERFRQLFAAFG---------------TLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQKHFNKSFIDTSRITVEFCKSFGDPAKPRAWSKHAQKP--------SQPKQPPKDSTTPEIKKDE-KKKKVAGQLEKLKEDTEFQEFLSVHQRRAQAATWANDGLDAEPS----------KGKSKPASDYLNFD----SDSGQESEEEGAGEDLEEEASLEPKAAVQKELSDMDYLKSKMVKAGSSSSSEEEE-SEDEAVHCDEGSEAEEEDSSATPVLQERDSKGAGQEQGMPAGKKRPPEARA------------------------------------------------------ETEKPANQKEPTTCHTVKLRGAPFNVTEKNVMEFLAPLKPVAIRIVRNAHGNKTGYIFVDFSNEEEVKQALKCNREYMGGR--YIEVFREKN--VPTTK-GAPKNTTKSWQGRILGENEE-----EEDLAESGRLFVRNLPYTSTEEDLEKLFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEVDGQVFQGRMLHVLPST-IKKEAS-EDASALGSSSYKKKKEAQDKANSASSHNWNTLFMGPNAVADAIAQKYNATKSQVFDHETKGS-VAVRVALGETQLVQEVRRFLIDNGVSLDSFSQAA--AERSKTVILVKNLPAGTLAAQLQETFGHFGSLGRVLLPEGGITAIVEFLEPLEARKAFRHLAYSKFHHVPLYLEWAPVGVFSSTAPQKKKLQDTPSEPMEKDPAEPETVPDGETPEDENPTEEGADNSSAKMEEEEEEEEEEEES--LPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAG--VLLSMGFGFVEYRKPEQAQKALKQLQGHVVDGHKLEVRISERATKP-AVTLA-RKKQVPRKQTTSKILVRNIPFQAHSREIRELFSTFGELKTVRLPKK-MTGTGTHRGFGFVDFLTKQDAKRAFNALCHSTHLYGRRLVLEWADSEVT--LQALRRKTAAHFH---EPPKKKR-SVVLDEILEQLEGSDSDSEEQTLQL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QF98-1", "uniprot_id": "F1QF98_DANRE", "id": "F1QF98-1", "name": "Probable RNA-binding protein 19", "aln": "MSRLIVKNLPNGMKEDRFRKMFADFG---------------TLTDCALKFTKDGKFRKFGFVGFKTEEDAQKALKHFNKSFVDTSRVTVELCTDFGDPNKARPWSKHTRQP--------SSKKDTEEKKTHEQGEKEKKKPKKILNVLGDLEKDESFQEFLAVHQKRGQVPTWANDTVEATAVRPEMEKKKEKKQKAAVEDDYLNFD----SDESEESSDDGEDAADEEDKQDNEKEALKTGLSDMDYLRSKMVEK-SDMLDEKDDDSSASAADENEEDEGKEEEESIVQHADS------AYESGEKTSSQKS-------------------------------------------------------------TRPA--IEPTTEFTVKLRGAPFNVKEQQVKEFMMPLKPVAIRFAKNSDGRNSGYVYVDLRSEAEVERALRLDKDYMGGR--YIEVFRANN--FKNDRRSAKRSEMEKNFVRELKDDEE-----EEDVAESGRLFIRNMPYTCTEEDLKEVFSKHGPLSEVLFPIDSLTKKPKGFAFVTYMIPENAVSALAQLDGHTFQGRVLHVMASR-LKKEKADQGPDAPGSSSYKRKKDAKDKAASGSSHNWNTLFLGTSAVADAIAEKYNTTKSQVLDHESDGS-LAVRMALGETQIVQETRQFLLDNGVSLDSFSQAS--GERSKCVILVKNLPSGVQVADLEALFSPHGSLGRVLLPPSGLTAIVEFLEPTEAKRAFMKLAYTKFQHVPLYLEWAPVAVFTTPSAPRPEPQ-TKEKSAVKNDSVQN---------------------------EEEEEEEEEDDQILPGSTLFIKNLNFITSEETLQKTFSKCGVVKSCTISKKRDKAG--KLLSMGYGFVQYKTPEAAQKAMRQLQHCTVDEHQLEVKISEREVKS-GVAQAKRKKQTARKQTTSKILVRNIPFQATVKELRELFCTFGELKTVRLPKK-GIG-GSHRGFGFIDFLTKQDAKKAFSALCHSTHLYGRRLVLEWADAEET--VDDLRRKTAQHFH---DAPKKKRKAEVLEGILEQMEVGDGDGE------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VT19-1", "uniprot_id": "Q9VT19_DROME", "id": "Q9VT19-1", "name": "RRM domain-containing protein", "aln": "MSRIIVKQLPKHITEDKLRQIFGAQG---------------TITDLQLKYTPDGKFRQFCFVGYSTEEEAQSAIRHFDNTCIQTSRVRVESCAALGSEDKPQSWSKYAKDSKKNLDKLKEKEREAAAKAKESEKKKKKDKVDKVDQILSRHKDDPEFQEFLEAHDKSR--TLWGND---------------------------LGIN------KNRENEEE-DDEEQEESRAARDDSGVDADAG-------------------DEDGSGDEADEEEDTDKLAEKPISDLEYMKS-----LMATTSGEATAKKP--------------------------------------------------------------KAKADKSNLELFTIKIHNVPYNTKRQEVLKFFKPLKPYSVRLPSKVHG----FCYVGFKTEKDMAKGMLKNKSFIKGKQVFFSDFTEKNKVTKASKSGQPLAPAAVDAGNAKWKHQQDSLSKEDDISESGRIFFRNLAYTTTEEDLRKLFEQFGPVVEVNLPLDKLTRKIKGFGTVTYMMPEHALKAFNTLDGTDFHGRLLHLLPSKDIEKNPKEDLDENDASLSFKEKKALKLKKNAQKPIGWNTLFLGANAVAEILAKQFKTSKERILDTSDGGSSAAVRLALGETQVVIEMKRFLEEEGVRLDAFDEPA--KKRSNTVILAKNLPAATEISEITPIFSRFGPIGRIVLPPSGVTALIEYCDPLEARQAFKKLAYSKFKNAPLYLEWAPEQVFTKTLSGEPVIPKSEPKPKEEVKPEEKPIVN------------------DAKPDEEDSRAEDADDEPEPNTTLFLRNLNFKTVQETVEKHFRHLGSIHTVEIAKRRDPENPREFKSLGYGFIQFKKSSVAEHALKNLQLTHIDGNPVELKRSDRVLKTQDNDGAQRRLASQKKQTGTKILVRNIPFQAQYREVRDIFKAFGELRSLRIPKKATTGEDAHRGFGFVDYMSKAEAKRAFDALSASTHLYGRRLVLEWSANDDNQDVEELRKRTAAKFDGSQAATAAKRSRKSFFDVEGSVQPNQDDDEEEEQ--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06106-1", "uniprot_id": "MRD1_YEAST", "id": "Q06106-1", "name": "Multiple RNA-binding domain-containing protein 1", "aln": "MSRIIVKGLPVYLTDDNLREHFTKRLRQKHSHQAVNGSGPDLITDVKILRDRNGESRRFGFIGYRNEEDAFDAVEYFNGSFINTSKIEVSMAKSFADPRVPQPMKEKRREALK------RFREKEEKLLQEENRKKKKVDENKHSNIDDEIRKNKQLQEFMETMKPSSQVTSWEKVG-------------------------------------IDKSIEDEKLKREEEDSSVQGNSLLAHALALK------------------EENNKDEAPNLVIENESDDEYSALNRNRDE--------------------------------------------------------------------------------DQEDAGEEEKMISISNLKDTDIGLVNDDANSDEKENEKRRNLAQDEKVSDLDWFKQRRVRIKESEAETREKSSSYATEQNESLDTKKEEQ---------PERAVPQKTDEELAIEKIN----------QTGRLFLRNILYTSKEEDFRKLFSPFGELEEVHVALDTRTGQSKGFAYVLFKDSKNAVNAYVELDKQIFQGRLLHILPGE-EKKSHRLDEFDLKNMPLKKQKELKRKAAASRQTFSWNSLYMNQDAVLGSVAAKLGLEKSQLIDAENSSS--AVKQALAEAHVIGDVRKYFESKGVDLTKFSQLKSTNQRDDKVILVKNFPFGTTREELGEMFLPYGKLERLLMPPAGTIAIVQFRDTTSARAAFTKLSYKRFKDGIIYLERGPKDCFTKPAEADDLINNTSAKEEENPVEVKPSSND--------------LMEANKDVTEGSSNAHDEDVIDGPTVSIFIKNLNFSTTNQNLTDRFKVFTGFVVAQVKTKPDPKHQGKTLSMGFGFVEFRTKEQANAVIAAMDGTVIDGHKIQLKLSHRQASQ------SGNTKTKSNKKSGKIIVKNLPFEATRKDVFELFNSFGQLKSVRVPKK---FDKSARGFAFVEFLLPKEAENAMDQLHG-VHLLGRRLVMQYAEEDAVDAEEEIARMTKKVRK---QVATNEMAALRNGGGRKKLDVDDEENEGF----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:*** ** :.::.:*: * :** : :*: *:* *:*: .**:* * .:*. : ::*::: *. . :.. .:. .: :.. .. : :*.: . . ..: .:***: . . * : :. :: **. . . : . .: . .* . .: :: : .. : . :::.. . ..:. . : : . : . : . . . .: : :. :: . .. : ::**:*.**: ** .***:.::*. .* : *: .:*. * : ***. : : .::*:.* :* *:**:**::.. :*. : . *.*: : .. .**:*::. .** :* : *.:::* . .* **: **.*:::: : : :: .:** * *.: :*.. ***.**:* .. :: * .* : *:::* .* *:::: :. .*: ** :*:*.:*:. :*** .* * . : : * ... .: : * ::*::**** * ::.: * . : .: . *:*:**::::. . *: .: :: :* : :::: *.* . . ::. **:*:*:**:* ::: ::* :**:*:::*:*** : ***.*:::: :*:.*:. * .** *****:::: : : : : * . . : .:: : .. ", "identical_positions": 150, "similar_positions": 302, "identity": "13.88%" }, { "cls_id": "homologset.agr.RGD:1308929", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A572-1", "uniprot_id": "A0A8I6A572_RAT", "id": "A0A8I6A572-1", "name": "", "aln": "-------------------------------MNPVYSPVQPGAPYGNPKNMAYTGYPTAYPAAAPAYNPSLYPTSSPSYAPEFQFLHSAYGISPLFPLSFPSGYHDATLLMKQAWPQNSSSCG-TEGTFHLPVDTGTENRTYQASSAAFRYTAGTPYKVPPTQSNTAPPPYSPSPNPYQTAMYPIRSAYPQQNLYAQGAYYTQPVYAAQPHVIHHTTVVQPNSIPSAIYPAPVAAPRTNGVAMGMVAGTTMAMSAGTLLTTPQHTAIGAHPVSMPTYRAQGTPAYSYVPPHW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BGZ2-1", "uniprot_id": "F168A_MOUSE", "id": "Q8BGZ2-1", "name": "Protein FAM168A", "aln": "-------------------------------MNPVYSPVQPGAPYGNPKNMAYTGYPTAYPAAAPAYNPSLYPTNSPSYAPEFQFLHSAY----------------ATLLMKQAWPQNSSSCG-TEGTFHLPVDTGTENRTYQASSAAFRYTAGTPYKVPPTQSNTAPPPYSPSPNPYQTAMYPIRSAYPQQNLYAQGAYYTQPVYAAQPHVIHHTTVVQPNSIPSAIYPAPVAAPRTNGVAMGMVAGTTMAMSAGTLLTTPQHTAIGAHPVSMPTYRAQGTPAYSYVPPHW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92567-1", "uniprot_id": "F168A_HUMAN", "id": "Q92567-1", "name": "Protein FAM168A", "aln": "-------------------------------MNPVYSPVQPGAPYGNPKNMAYTGYPTAYPAAAPAYNPSLYPTNSPSYAPEFQFLHSAY----------------ATLLMKQAWPQNSSSCG-TEGTFHLPVDTGTENRTYQASSAAFRYTAGTPYKVPPTQSNTAPPPYSPSPNPYQTAMYPIRSAYPQQNLYAQGAYYTQPVYAAQPHVIHHTTVVQPNSIPSAIYPAPVAAPRTNGVAMGMVAGTTMAMSAGTLLTTPQHTAIGAHPVSMPTYRAQGTPAYSYVPPHW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BKV9-1", "uniprot_id": "A0A8M2BKV9_DANRE", "id": "A0A8M2BKV9-1", "name": "", "aln": "MASGHSTDKFSFLYPTDSSQSVKSKNRLSSTMNPVYSPVQPGTPYGNPKNMAYTGYPGGYPTTAPAYTANLYQTGSPGYPP--------------------------VLLVKQAWPQTASAPGPAEGSYDLAVDAGSESRQYQASSTAFRYTAGTPYKVPPTQSNGAPPPYSPSPNPYPTAMYPIRSAYPQQNLYAQGAYFTQPVYAAQPHVIHHTTVVQPNSIPSAIYPAPVPAPRSNGVAMGMVAGTTMAMSAGTLLTTPQHTQIGAHPVTVPTYRPQGTPGYSYVPPHW", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***********:************** .**::****...** *.**.*.* .**:******.:*: * :**::.*.**:*:*.* *****:****************** ************ *********************:********************************.***:*************************** ******::****.****.********", "identical_positions": 196, "similar_positions": 31, "identity": "67.12%" }, { "cls_id": "homologset.agr.RGD:1308930", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LMU7-1", "uniprot_id": "A0ABK0LMU7_RAT", "id": "A0ABK0LMU7-1", "name": "", "aln": "MEASGEQLHRSEASSSTSSEDPPPAEELSVPEVLCVESG-----TSEVPIPDDQLQDRLLSAQKVAALP-------EQEELQEYRR-SRVRSFSLPADPILQAAKLLQQRQQ-----AGQPSSEGGEPAGDCCSKCKKRVQFADSLGLSLASVKHFSEAEE--------PQVPPAVLSRLHSFPLRAEDLQQLGELLAVAKVPAPLLTPRAQLRPLFQLP----------GLI-AAEERLRRQRVCLERVQCSQPP-----------RAEVTGSGRVISCPGPRAVAVRYTFTEWRTFLDVPAELH-----------------------------------------------------------------------------PESLEPLSP-VRSGNSGPGAEDSEGEPGTERFCFSLCLPPG--------------------------------------------------------------------LQPKEGEDADTWGVAIHFAVCYRCEQGEYWDNNEGANYTLRYVCSTDPL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CW07-1", "uniprot_id": "PP13G_MOUSE", "id": "Q9CW07-1", "name": "Protein phosphatase 1 regulatory subunit 3G", "aln": "MDPSGEQLHRSEASSSTSSGDPQSAEELSVPEVLCVESG-----TSETPIPDAQLQDRPLSPQKGAALP-------EQEELQEYRR-SRARSFSLPADPILQAAKLLQQRQQ-----AGQPSSEGGAPAGDCCSKCKKRVQFADSLGLSLASVKHFSEAEE--------PQVPPAVLSRLHSFPLRAEDLQQLGGLLAVATMPDPLLVPCARLRPHFQLP----------ELR-AAEERLRRQRVCLERVQCSQPP-----------RAEVTGSGRVISCPGPRAVAVRYTFTEWRTFLDVPAELD-----------------------------------------------------------------------------PESVEPLPP-LQSGDSGSKAEDSEEGPGTERFHFSLCLPPG--------------------------------------------------------------------LQPKEGEDAGAWGVAIHFAVCYRCEQGEYWDNNEGANYTLRYVCSTDPL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B7ZBB8-1", "uniprot_id": "PP13G_HUMAN", "id": "B7ZBB8-1", "name": "Protein phosphatase 1 regulatory subunit 3G", "aln": "MEPIGARLS-LEAPGPAPFREAPPAEELPAPVVPCVQGGGDGGGASETPSPDAQLGDRPLSPKEEAAPQ-------EQEELLECRRRCRARSFSLPADPILQAAKFLQQQQQQAVALGGEGAEDAQLGPGGCCAKCKKRVQFADTLGLSLASVKHFSEAEE--------PQVPPAVLSRLRSFPMRAEDLEQLGGLLAAAAVAAPLSAPPSRLRPLFQLP----------GPS-AAAERLQRQRVCLERVQCSTAS-----------GAEVKGSGRVLSCPGPRAVTVRYTFTEWRSFLDVPAELQ-----------------------------------------------------------------------------PEPLEPQQPEAPSGASEPGSGDAKKEPGAECFHFSLCLPPG--------------------------------------------------------------------LQPEDEEDADERGVAVHFAVCYRCAQGEYWDNNAGANYTLRYARPADAL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B9X2-1", "uniprot_id": "A0A8M2B9X2_DANRE", "id": "A0A8M2B9X2-1", "name": "", "aln": "-------MRMWSCYWVTSPHTHLLIQRGSPGVTLAVIGDYR---TEMMSIMNAEQMENGLDSDDDLQPE-------EIPEYLKDRR----RAKSLPAYPEQASLYHQISQN------------------------CRKRVKFADALGLNLASVKHFSTSED--------PQIPAKVFNRLKSFPLQKE-----REFIDDLCVNIRSSLALDYLVPTFKTP----------VDSGDQETRLARGRVALESVTVTQ--------------FDVRG---IIRATGGREVGVRYTFNDWLSFVDAQAIP-----------------------------------------------------------------------------------------------------VATEDTTRYSFTMYTPPF--------------------------------------------------------------------LDP---------SASVHFAVYMKDDNSEFWDNNDGLNYSLKYHSSSPSETAAFHAV-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P28006-1", "uniprot_id": "GAC1_YEAST", "id": "P28006-1", "name": "Serine/threonine-protein phosphatase 1 regulatory subunit GAC1", "aln": "-MVIQTATTLSPAKARPSFPHNDLIKSMSDSLISRPTHPPIRKLKSSLKISHPEPISRSKSEIFCTSPEKNVRFAIELTTVKRFDKNAEPSSISNENSPTLSPVDSNTAADD-VQLFNNEDCWFNDSSLVTNLLKNEKKFRYMNSLNNMFKLDLYDSEDEDDIDEHINSQAEYGYTYNSLSTRGKTSENKSATSSLATQATNICDWKLHCTDLVPFKIAPPLFTKTLSASDLQGQLTKYLNGQNVKLHSLTQLGDD-----------SSKITGLVYVKNLSFEKYLEIKFTFNSWRDIHYVTANFNRTINSNVDEFKFTIDLNSLKYILLIKRIITMEKNTSSCPLNIELCCRYDVNNETYYDNNNGKNYHLFMTTFKKGGETKEKIPVVVEPASQTDAAMSPKEMKARFVSSNPTLSRFLPQSRKFSEDTDYYNTSPLKHLYHNDTTSWVKPKRLNVVLDKLENATPPPPSSALANDTARTGKITKDKNNVLAPPTASNSIDLPILGSQHQSLYSGSSSYSSSSSSISSSLSFASSNNSSTNSSSASCSFPLTELDNFDYANLYEPNDTFTTANLFNHSLNSLMPEISTPSFFGGFRNENTINNNDSKNLVTSLEDS--YEDKQSVITDTTMDENNKTSTINNSTDTLIKPSKENGTVKENKSSANSTSAPSSSQNRASTILNDHSNGKSDLKYVNYQSLLDSHCFYN--HPSSPNLQSTSFSSAAPFSGISQASDIFDYENEDSDSNQIAGEIDNNSFPPHFYLDEDDKSACLSDDALIDHHRNTNPFINTFSSSPPILSQEVDRWRL-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q06216-1", "uniprot_id": "PIG1_YEAST", "id": "Q06216-1", "name": "Serine/threonine-protein phosphatase 1 regulatory subunit PIG1", "aln": "---------MPYSHGKKLKPSLKLAKTISTSSFVSSTTS-----NSFSPLEDSTSASSSTSSSSSGKSVR---FAAHLYTVKKFNTKLAPISISEKAASNLTRNLHNNAIP------------------LTFPFIGGEDHRYSLDILDYSDLEYDNKDVEYD-------NESDVEDNAMLMHDRSMFIEKEILCFGEEETFDMADWKLVSNNLNPFKSDYKVDVT-----GLEDKIFKYLNGQNIKVHSLELSDPVSYEDICSNNFGNCQIWGLIFVNNLNFEKKIEIKFTLNNWADIHYINAHYNKSVTPHVDEFKFIIDISALKLN------------------------------------------------------LISKNLIYTNFFERKTTCLLNLQFCCRYDVNGFEYRSFYDNN--------------------------------------------------------------DYKNYEITISLSAINLNRAVSNSSIFNSNLGPSKMGASNAEVTMSKNNENSKKPLRKFIKDTDYYNDSPLKHKFYQSFETKAACKTEPVSQTFKAETIDCEIEPFNYFFEPPDSQTNEDMSDSSYDLSLQDFNYWEFSNHGLGKALADSDILQFKNYPKPEPFSRPPIIDDTFTLNTDDRTLGSKTQKLEDNLAKEWKSAKTRTTLNETPLHDDEHRTSFTYTTWNNSTDTLMKRKEERPVESASCSQLSIATIKAEEDLLYQDYINSGRESSSPEISPLNTTTSLPFFPGDNMSDSSGEYEERTSLSPNKIHIFRDYFYKSPSP", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . . . . . . . : * . : :: : . * * * * * .: :. : .: * : : : :::*:..* : * : .. .. . : . . ", "identical_positions": 10, "similar_positions": 42, "identity": "1.23%" }, { "cls_id": "homologset.agr.RGD:1308931", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4A5C9-1", "uniprot_id": "D4A5C9_RAT", "id": "D4A5C9-1", "name": "", "aln": "-------------------------------------------MANPMMSVNSLLT-AGPQRVSMVPSPFGPPIGDRDALP-STIAPTDPSQFCVPSQFGSSGLPSANTPNPLPGHFYS--GWGILPPEPIKAVTTRNEMFERHHAARAEMEMYSLYQQRRMERVNPKGLSGLGIPLFYGSGCLGGPAGFQGRSTLPAS-DVHVHRSTFRHLQGNPVLLAT-RPHFTECWGQKYR-LRRGTVYQKPPEIDTESFKSQADEKSSGQMPTAPYEEEEYIKD--PEIGVDNQQEPRVTDGNPTAVLANPHGEPQPNQRKPS-----SMEAKAWDDGKGEPSEQGYEGCDEKNGVCLPASTLPLPGTQEPVALQEN----------------RPLS-DIHKWTVDDVYNFIRSLPGCSDYAQVFKDHAIDGETLPLLTEQHLRGTMGLKLGPALKIQSQVSQHVGNMFCKKL------PSLPSHARQAFDQPADTSPLLAI------GSWRDGLSIPGSQDIMSPERAEQDVMRN--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C8Y5-1", "uniprot_id": "SAMD7_MOUSE", "id": "Q8C8Y5-1", "name": "Sterile alpha motif domain-containing protein 7", "aln": "-------------------------------------------MTNPMMSVSSLLT-SGQQKVPMVPSPFGPPIVDRDVLS-SSIAPTDPSQFCVPSQFGSSGLPNANMPNPLSSHFYS--GWGILPPEPIKAVTTRNEMFERHHAARAEMEMYSLYQQRRMERVNPKGLSGLGIPLFYGSSCLGGPTGFQGRSTLPAS-DVHLHRSTFRHLQGNPILLAT-RPHFTECWGQKYR-LRRGAVYQKPPESDTESFKSQAEEKSSSQMPTLSYEEEEYIKD--PDIEVDNQQKPRVADGKPTTVPANPHGELHTHQRKPS-----SLEANAWDDGKGKPSEQVYEGCDGKNGVFRPVSILPLSGTHEQVALREN----------------CSLS-DIQKWTVDDVYNFIRSLPGCSDYAQVFKDHAIDGETLPLLTEQHLRGTMGLKLGPALKIQSQVSQHVGNMFCKKL------PSLPTHARQAFDQPADTSPLLDM------SSWSDGLSIPGPQDLLSPKRTEQDVMRN--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z3H4-1", "uniprot_id": "SAMD7_HUMAN", "id": "Q7Z3H4-1", "name": "Sterile alpha motif domain-containing protein 7", "aln": "------------------------------------------------MAVNPLLTPTGQQTIPLIPSPFGPPTVDRDVLP-STVAPTDPRQFCVPSQFGSSVLPNTNMANVLSSRIYP--GWGILPPESIKAVARRNEMIQRHHTARTEMEMYAIYQQRRMEKINPKGLAGLGIPFLYGSSVPAAPAAYHGRSMLPAG-DLHFHRSTLRNLQGNPMLAAT-APHFEESWGQRCRRLRKNTGNQKALDSDAESSKSQAEEKILGQTHAVPYEEDHYAKD--PDIEAPSNQKSSETNEKPTTALANTCGELEPTHRKPWGSHTTTLKAKAWDDGKEEASEQIFATCDEKNGVCPPVPRPSLPGTHALVTIGGN----------------LSLDEDIQKWTVDDVHSFIRSLPGCSDYAQVFKDHAIDGETLPLLTEEHLRGTMGLKLGPALKIQSQVSQHVGSMFYKKT------LSFP--IRQAFDQPADTSPLLDP------NSWSDTMNIFCPQDTIIPKGIERGSMRN--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B7T1-1", "uniprot_id": "A0A8M3B7T1_DANRE", "id": "A0A8M3B7T1-1", "name": "", "aln": "MTPREQLRKITALGEQGALDEKHWYRLVNGMSAGAELRQRQELMMRNQMAMAPQILAQGQQRLQGVPAQFDPRFMERELVPPADMVSADARQIHMGAHLGQQLPPNS---NVIPGRGYPGTGYNFLQTESMETVARRQELIHKQNIAR--MEMNAILHQKELENAHQKGLISIENPMMYQG-IQPNPMAFRGRQRLPDGHDVFVHRTALEDLHANSLLMSSPYPPISTLQRERGRRTGRRTTNHKSSDSNITLPKGQSEEKNIEQSPGAASGEEKEAEGKGSDATSSKPHQTKAETELSSGGSRKGFKEGEPGIRKACISGQEGCAEVSNCNASTSDKDMSNPCSAFQDKFLYPSTSGPLTGMPYMLPVPGNGLLPLGPPNMFLNGEEMPSSEDIRKWTVDDVYSFISEIPSCAEYAQTFKEHMIDGETLPLLTEDHLLDTLGLKLGPALKIRSQLSRRLGNMFYNMMNLPLPVSGLQPPPEKSVDRSSDISSPLNCNSVEMLSSPRDTDALKAAEPVSEADNLSPSQMSETT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:: . : * * : :*: *.* :*: :. : :..:*. *: : :::*.. *.: * :..: *. *:.:* .*.:::*: *:*::.::: ** *** :: :*:.:*. : *** .: *::* . * .::**. ** . *:..**:::..*:.*.:* :: * : :: * : : :*. : : *.*::** * . *:. :. .: . ::. .: : * .. **. : :.. . .: . :: . * . .*.* :.: * . . **:*******:.** .:*.*::***.**:* ***********:** .*:**********:**:*:::*.** : .: .::.*:.:* *. * .* * : .: .. . . * : ", "identical_positions": 114, "similar_positions": 167, "identity": "21.39%" }, { "cls_id": "homologset.agr.RGD:1308932", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P59326-1", "uniprot_id": "YTHD1_MOUSE", "id": "P59326-1", "name": "YTH domain-containing family protein 1", "aln": "MSATSVDPQRTKGQDNK---------------------------VQNGSLHQKDAVHDNDFEPYLSGQSNPSNSYPSMSDPYLSSYYPPSIGFPYSLSEAPWSTAGDPPIPYLTTYGQLSNGDHHFMHDAVFGQPGGLGNNIYQHRFNFFPENPAFSAWGTSGSQGQQTQSSAYGSSYTYP-PSSLGGTVVDGQTGFHSDSLNKAPGMN----SLEQGMVGLKIGDVTTSAVKTVGSVVNSVALTGVLSGNGGTNVNMPVSKPTSWAAIASKPAKPQPKMKTKSGPIVGGALPPPPIKHNMDIGTWDNKGPAPKASAPQQTPSPQAAPQPQQVAQPLPVQPPPLVQPQYQSPQQPLQPRWVAPRNRNAAFGQSGGANSDSNSVGNAQPTSAPSVESHPVLEKLKAAHSYNPKEFDWNLK-SGRVFIIKSYSEDDIHRSIKYSIWCSTEHGNKRLDGAFRSMSSKG-PVYLLFSVNGSGHFCGVAEMKSPVDYGTSAGVWSQD-KWKGKFDVKWIFVKDVPNNQLRHIRLENNDNKPVTNSRDTQEVPLEKAKQVLKIIASYKHTTSIFDDFSHYEKRQEEEEVVRK--------------------ERQNRNKQ-------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7F2Q6-1", "uniprot_id": "F7F2Q6_RAT", "id": "F7F2Q6-1", "name": "YTH domain-containing family protein", "aln": "MSATSVDPQRTKGQENKGSGWLWRRVSQLAVDREALPSTLSYSHLQNGSLHQKDAVHDNDFEPYLSGQSNPSNSYPSMSDPYLSSYYPPSIGFPYSLSEAPWSTAGDPPIPYLTTYGQLSNGDHHFMHDAVFGQPGGLGNNIYQHRFNFFPENPAFSAWGTSGSQGQQTQSSAYGSSYTYP-PSSLGGTVVDGQTGFHSDTLNKAPGMN----SLEQGMVGLKIGDVTTSAVKTVGSVVNSVALTGVLSGNGGTNVNMPVSKPTSWAAIASKPAKPQPKMKTKSGPIVGGTLPPPPIKHNMDIGTWDNKGPAPKASAPQQTPSPQAAPQPQQVAQPLPVQPPPLVQPQYQSPQQPLQPRWVAPRNRNAAFGQSGGANSDSNSVGSAQPTSAPSVESHPVLEKLKAAHSYNPKEFDWNLK-SGRVFIIKSYSEDDIHRSIKYSIWCSTEHGNKRLDGAFRSMSSKG-PVYLLFSVNGSGHFCGVAEMKSPVDYGTSAGVWSQD-KWKGKFDVKWIFVKDVPNNQLRHIRLENNDNKPVTNSRDTQEVPLEKAKQVLKIIASYKHTTSIFDDFSHYEKRQEEEEVVRK--------------------ERQNRNKQ-------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BYJ9-1", "uniprot_id": "YTHD1_HUMAN", "id": "Q9BYJ9-1", "name": "YTH domain-containing family protein 1", "aln": "MSATSVDTQRTKGQDNK---------------------------VQNGSLHQKDTVHDNDFEPYLTGQSNQSNSYPSMSDPYLSSYYPPSIGFPYSLNEAPWSTAGDPPIPYLTTYGQLSNGDHHFMHDAVFGQPGGLGNNIYQHRFNFFPENPAFSAWGTSGSQGQQTQSSAYGSSYTYP-PSSLGGTVVDGQPGFHSDTLSKAPGMN----SLEQGMVGLKIGDVSSSAVKTVGSVVSSVALTGVLSGNGGTNVNMPVSKPTSWAAIASKPAKPQPKMKTKSGPVMGGGLPPPPIKHNMDIGTWDNKGPVPKAPVPQQAPSPQAAPQPQQVAQPLPAQPPALAQPQYQSPQQPPQTRWVAPRNRNAAFGQSGGAGSDSNSPGNVQPNSAPSVESHPVLEKLKAAHSYNPKEFEWNLK-SGRVFIIKSYSEDDIHRSIKYSIWCSTEHGNKRLDSAFRCMSSKG-PVYLLFSVNGSGHFCGVAEMKSPVDYGTSAGVWSQD-KWKGKFDVQWIFVKDVPNNQLRHIRLENNDNKPVTNSRDTQEVPLEKAKQVLKIISSYKHTTSIFDDFAHYEKRQEEEEVVRK--------------------ERQSRNKQ-------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VBZ5-1", "uniprot_id": "YTHDF_DROME", "id": "Q9VBZ5-1", "name": "YTH domain-containing family protein", "aln": "--MSGVDQMKIPGNTAKS--------------------------VEERNIPWSQQVDEASYEN----LSSPTHDEVSGNDNSMQFQYPPFNFKENCNTPWNNMNKGRKANANHDSYRRHGHSIPNNTRRDEHQVNPWNSRKPAAQSFRNENDQPSTKLDNRTSDEAQNQEVVAAPKKTTWASIASQPAKLTSRAASTTSNSKKKGPGMPPPPMVPGKHNLDVNVWDLPNNKPPPVPSPPSPIDLG---YSDLSSDFSISSNTAPPLGARAEKVHKDTENFLKYEHKGLGNNNNFSRAKVSPTGPVRRNLGPQQPVHHAAPRPATNAGPFGPPNARRHDGGP----HPSRNSERSGNYSSFRGSEFESASKFEYRDEN-QSRPVEATSATEELPVDSQLVLDELKDKNNYNPKVLDLKKAGSARFFVIKSYSEDDIHRSIKYEIWCSTDHGNKRLDDAFKERHEEGGNIMLFFSVNGSGHFCGMAQMMTPVDYNSTSSVWSQD-KWRGKFKVKWIYVKDVPNGTLRHIRLENNENKSVTNSRDTQEVPNDKGIEVLQILHSYNHSTSIFDDFFHYEKKQEEEVSSKRPPMHGPDGNNHAPAPLARSFNRQADDKDRDRDGRGGMSQKHFNSGGGAGFRNPGHRGGAGSGGSHNNYSEYRRGFDIHKSSSDYQFKDRDGPDFDRENDFGSHYGSNNRKNEYKHNNTNKARLKTRDRDFSTEQIKIGVRFKDTDKDKMRSNEYS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06390-1", "uniprot_id": "MRB1_YEAST", "id": "Q06390-1", "name": "Methylated RNA-binding protein 1", "aln": "------------------------------------------------------------------------------------------------------------------MNQIWSTGPPNFYFNSEWKENKRNDR--------------------------------------------------------TIEDSLRELDGLIH---SLERTHIEVQTNPKLKN-------------------------------DVTALNDINKKENKEEITHENYTHQINSIPLTSSNLNRHFSFSRDYN---------------------------------------------------------------QSDNSNNNYYREYLSKPRYLQQSTKEQTFNEINKRKSAAIIPPWLNIPENSRFFVIKSSSLKHVKRSFYNGIWSSTHFGNKRLSEAYKKLNSGA-KVFLFFSINTSGRFCGVAEMVSDLKMDLDTSIWEDEQKYGKAFKVRWVIVRDINNRSLKRFLIPSNEMKPITHSRDTQEIPYSIGISIINLFKTQDS-----DIFSFLDETYE------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : .. .:: : *: : : :: .. .. .* * . . . . : * : . . : .. .. .::::: :. : ..*.*:*** * ..::**: **.**..*****. *:: . . : *:**:* **:***:*:* : :. . :.:*.:: *: *.*:*: *:*: * *::: : .*: *.:*:******:* . . .::::: : . * * . :: * ", "identical_positions": 55, "similar_positions": 103, "identity": "7.42%" }, { "cls_id": "homologset.agr.RGD:1308935", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "F1LU70-1", "uniprot_id": "F1LU70_RAT", "id": "F1LU70-1", "name": "", "aln": "MAALDSDSEEDLISYGTGLEPLEEGERP-KKPIPLQDQTVRDEKGRYKRFHGAFSGGFSAGYFNTVGSKEGWTPSTFVSSRQNRAD-KSALGPEDFMDEEDLSEFGIAPKAIVTTDDFASKTKDRIREKAR-----QLAAAAAPIPGATLLDDLITPAKLSVGFELLRKMGWKEGQGVGPRVKRKARRQKADPG------VKIYGCALPPGGSEGSEDED---DDYLPDNVTFAPKDVMPVDFTPKDNVHGLAYKGLDPHQALFGMPGEHLNLFGGASEGTSHLLGDVGLSKGRK-LGISGQAFGVGALEEEDDDIYATETLSKYDTVLKDEEPGDGLYGWTAPKQYKNHKEPERDLRYVGKILEGFSLASKPLSSKKIYPPPELPRDYRPVHYFRPVVAATSKNAHLLQVLSESSGKAGQDMGTHSRHQLNASKRGELLGEMPVQGSATSVLEFLSQKDKERIKEVKQATDLKAAQAKARSLAQSASSSRAQAS-TPDPGHSSWHLALGSG-----TVTTRASNFKPFAKDPEKQRRYEEFLVHMKKGQK---DALERCLDPNMTEWERSREREEFARAAQLYVSSNSTLSSRFTHAKEEDDSDQVEVPRDQENDLSDKQSAVKMKMFGKLTRDTFEWHPDKLLCKRFNVPDPYPGSTLVGLPRVK-RDKYSVFNFLT----------------------LSEPASLPTAPVPSEK--APQQRGPDKSRKPS--------RWDTSKQEKKEDSISEFLSQARSKVGPSKQESSALGSKEE-QASEPHPDMTVDKAVDAQPD--REGSRPSMDLFKAIFASSSDEKSSSSEEEQDDSEDSQ-----EHTEEASLKGSQEAAVGETS-LIHAAEQEPGEPATPFPIQKVQIDE-REEFGPRLPPVFCPNVRQKLEIPHKEKPKKSKERHRSKKEHRRKREKKKKHKKHKHKSKQKNKKSEKNSSSESTDSSDSGSDAGGSTELSPQELLRRLKCLPLRRQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DBM1-1", "uniprot_id": "GPTC1_MOUSE", "id": "Q9DBM1-1", "name": "G patch domain-containing protein 1", "aln": "MAALDSDSDEDLISYGTGLEPLDEGERP-KKPIPLQDQTVRDEKGRYKRFHGAFSGGFSAGYFNTVGSKEGWTPSTFVSSRQNRAD-KSALGPEDFMDEEDLSEFGIAPKAIVTTDDFASKTKDRIREKAR-----QLAAAAAPIPGATLLDDLITPAKLSVGFELLRKMGWKEGQGVGPRVKRKARRQKPDPG------VKIYGCALPPGGSEESEDED---DDYLPDNVTFAPKDVMPVDFTPKDNVHGLAYKGLDPHQALFGMPGEHLNLFGGASEGTSHLLGDVGLSKGRK-LGISGQAFGVGALEEEDDDIYATETLSKYDTVLKDEEPGDGLYGWTAPKQYKNQKEPERDLRYVGKILEGFSLASKPLSSKKIYPPPQLPRDYRPVHYFRPVVAATAENAHVLQVLSESSGKAGQDVGTHSRHQLNASKRGELLGEMPIQGSATSVLEFLSQKDKERIKEVKQATDLKAAQAKARSLAQSASSSRAQAS-TPDLGHSSWHLALGGG-----TVTTRANNFKPFAKDPEKQRRYEEFLVHMKKGQK---DALERCLDPSMTEWERSREREEFARAAQLYVSSNSTLSSRFTHAKEEEDSDQVEVPRDQENDVSDKQSAVKMKMFGKLTRDTFEWHPDKLLCKRFNVPDPYPGSTLVGLPRVK-RDKYSVFNFLT----------------------LPEPAPLPTAPVPSEK--APQQRGSDKSRKPS--------RWDTSKQEKKEDSISEFLSQARSKVGPPKQESSALGSKEE-QAPEPRPDTTVDKAVDAQTD--GEGSRPSMDLFKAIFASSSDEKSSSSEEEQDDSEDSQ-----EHTEEASLKGSQEAAAGETS-VVLAAEPEPCEPATPFPIQKAQIDE-REEFGPRLPPVFCPNSRQKLEIPQKEKPKKSKERHKSKKEHRRKREKKKKHKKHKHKSKQKNKKSEKNSSSESTDSSDSGSDDGGPAELSPQELLRRLKCLPLRRQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BRR8-1", "uniprot_id": "GPTC1_HUMAN", "id": "Q9BRR8-1", "name": "G patch domain-containing protein 1", "aln": "MAARDSDSEEDLVSYGTGLEPLEEGERP-KKPIPLQDQTVRDEKGRYKRFHGAFSGGFSAGYFNTVGSKEGWTPSTFVSSRQNRAD-KSVLGPEDFMDEEDLSEFGIAPKAIVTTDDFASKTKDRIREKAR-----QLAAATAPIPGATLLDDLITPAKLSVGFELLRKMGWKEGQGVGPRVKRRPRRQKPDPG------VKIYGCALPPGSSEGSEGED---DDYLPDNVTFAPKDVTPVDFTPKDNVHGLAYKGLDPHQALFGTSGEHFNLFSGGSE-RAGDLGEIGLNKGRK-LGISGQAFGVGALEEEDDDIYATETLSKYDTVLKDEEPGDGLYGWTAPRQYKNQKESEKDLRYVGKILDGFSLASKPLSSKKIYPPPELPRDYRPVHYFRPMVAATSENSHLLQVLSESAGKATPDPGTHSKHQLNASKRAELLGETPIQGSATSVLEFLSQKDKERIKEMKQATDLKAAQLKARSLAQNAQSSRAQLSPAAAAGHCSWNMALGGG-----TATLKASNFKPFAKDPEKQKRYDEFLVHMKQGQK---DALERCLDPSMTEWERGRERDEFARAALLYASSHSTLSSRFTHAKEEDDSDQVEVPRDQENDVGDKQSAVKMKMFGKLTRDTFEWHPDKLLCKRFNVPDPYPDSTLVGLPRVK-RDKYSVFNFLT----------------------LPETASLPTTQASSEK--VSQHRGPDKSRKPS--------RWDTSKHEKKEDSISEFLSLARSKAEPPKQQSSPLVNKEEEHAPELSANQTVNKDVDAQAE--GEGSRPSMDLFRAIFASSSDEKSSSSEDEQGDSEDDQ-----AGSGEANFQSSQDTDLGETSSVAHALVPAPQEPPPSFPIQKMQIDE-REEFGPRLPPVFCPNARQTLEVPQKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSDSSDSQSDEE-TADVSPQELLRRLKSLPLRRQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VUA0-1", "uniprot_id": "GPTC1_DROME", "id": "Q9VUA0-1", "name": "G patch domain-containing protein 1 homolog", "aln": "-----MDEEEHLHRFGTPLPALQKDVVPAKKPVAIEDQIVKDENGK-RRFHGAFTGGFSAGFWNTVGSLEGWTPQTFKSSRGERASSKAQLKPEDFMDQEDLGEFGIAPQGIRTRDEFANEDEQKQRSDQRRRKLMQPELGVGAIPGLPVLEQLLRPVRDKVAVRILKSMGWKPGQGVGPRQTRKEKRQATARNSKEQYLMEHYGAEGLPSNKENKGEEDSNNEDEDDEDITFAPDDYEPIFYTPKENRFGMSYSGLNRDPILSKSS-----SSSAKPMQHINLFGEMEAQANKKQLSIRGQAFGVGAFEEEDEDIYARDDMTRYDFSLADKKP----------KQKKQQHVQQR------HVIDGFSEDNSPAVLQRPY-AIDLPRDFQPRNWLQRRSRFAPMDKERAQKLETASEYKRSGLG---RHDLNPDQRAQILGEQQQEEKTAEEQPKRNPFKDHSKSLMERINARTEGFTKGGVITENGEEQQTELAKEVKEANAAIQERAALKTKDLPSAMNSSSAFKPFIADEAKQLRYEKFVSSKLTDDKEITEFLARMQPVTLSLWDREMEKKEFIQAAKIYRPLVGLMNDRFVSEAN----VQAEKVEQQEKPPEERK--------IVMERTKTMWKPTALLCKRYNIAEPFGGAMLEPEKELKAKAKISVFDYLETSVNTKANFETPSIFPKHIEKSIPEKVETPPSPPPAPQPEAEIQDKPNTKEEPSKHTFVPKTPLEQAVDESRNKPISEKVDLFKSIFEDSDEEETELSEQDKLAILQESFGLPVTSTTSAAAQNVLRNTSPPRGIFASLFSPKIKDAAKEPAPTKFGPIEGSKLKIAYKPRKERLRNDRELAMAEVAPEDIYGPKLPTAPPQKPAAPEIQAEANIDDRLQQLWQQHAPKKRKAEKWVEKKCISGSEDSDASSSNESSSSDSSDDNDKRSKLSKPK--KSHKGSSSKKSKKSKLKSKKKSKKSEESKHKAKKKKKKSKH--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P12611-1", "uniprot_id": "WHI2_YEAST", "id": "P12611-1", "name": "Growth regulation protein", "aln": "------------------MDDIITQVSP-----------------------------------------DNAESAPILQEQQQQQNSQYEGNEEDYGDS-------LIHLNIQENHYFITRDQ------------------LMSLPESLLLCLFPSGVFLDRCGQVITNLTRDD---------------------------EVYIVNFPP--------------DCFEYIMEIYTKAHDDLYNHPVEKFFDRPSS-----------------SFVSNAKGFFGLSSNNSISSNNE-QDILHQKPAIIVLREDLDYYCVPQEEFQFDSTNEENNE-------------------------------------------------DLLRHFMAQVKMAAGSYLTSKTSIFQGLYSS--------------NRLKQQQQQQKIEKGSNSSSNTKSTSKKLGPAEQHLMDMLCSSGFTKETCWGNRTQETGKTVISSLS-------------------------------------------------------------LCRLANETTEGFRQKFN------------------------------------------------------------EAKAKWEAEHKPSQDNFITPMQSNISINSLSASKSNSTISTARNLT---------------------------SGSTAPATARD-----------KRKS---------RLSKLADNVRSHSSSRHSSQTRSKPPELPKLYDLVPKPNINAKLLLFWRKPARKCWWGEED---------IELEVEVFGSWKDESKK-----------------------------------------IIELILPTNVDPEAELHKIIVPVRLHIRRVWTLELSVIGVQ-----------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * :. . .: ..: :: . : **: *. : * . * .. : .:* :* : . . .:: .: . : * * * : : .. : * :: .. . . . . .: . ..: .* * .: .:.*: : . : ::* ::: :* *.: . : :. . : *: .:: : : : . . :. .. : . . . :... :. : * * . : : : . . *.. .: :. . : * . . *. * ..: .: . ..:. . .: :... *. . :* : : . : .. . . : : :*.. .: . * : . : ", "identical_positions": 29, "similar_positions": 157, "identity": "2.9%" }, { "cls_id": "homologset.agr.RGD:1308937", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZCG5-1", "uniprot_id": "D3ZCG5_RAT", "id": "D3ZCG5-1", "name": "", "aln": "MGSDRSALGRPGCAGSCLS-----SRASLLLLLLVLLDCLGGGTASEDAEVYAAENWLRLYGYLPQPSR--HMSTMRSAQILASALAEMQSFYGIPVTGVLDEETKTWMKRPRCGVPDQFGVR--------VKANLRRRRRRYTLTGKTWSNYHLTFSIQNYTEKLGWYNSMEAVRRAFQVWEQVTPLVFQEVPYDDIRLRRRAEADIMVLFASGFHGDSSPFDGVGGFLAHAYFPGPGLGGDTHFDADEPWTF--SSTDLHGISLFLVAVHELGHALGLEHSSNPSAIMAPFYQWMDTDNFQLPEDDLRGIQQLYGSPDGKPQPTRPLPTVRPRRPG---------------------------------------------------------------------------------------------------------------------------------------------------RPDHQPPRPPQPPHPGGKPERPPKPGPPPQ--PRATERPDQYGPNICDGNFDTVAVLRGEMFVFKGRWFWRVRHNRVLDNYPMPIGHFWRGLPG---NISAAYERQDGHFVFFKGNRYWLFREANLEPGYPQPLSSYGTDIPYDRIDTAIWWEPTGHTFFFQADRYWRFNEETQH-GDPGYPKPISVWQG-IPNSPKGAFLSNDAAYTYFYKGTKYWKFNNERLRME---PGHPKSILRDFMGCQEHVEP--------RSRWPDVARPPFNPNGGAEPETEDDSKEEDVGD--------KDEGS---RVVVQMEEVVRTVNVVMVLVPLLLLLCILGLAFALV-QMQRKGAPRMLLYCKRSLQEWV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54732-1", "uniprot_id": "MMP15_MOUSE", "id": "O54732-1", "name": "Matrix metalloproteinase-15", "aln": "MGSDRSALGRPGCTGSCLS-----SRASLLPLLLVLLDCLGHGTASKDAEVYAAENWLRLYGYLPQPSR--HMSTMRSAQILASALAEMQSFYGIPVTGVLDEETKTWMKRPRCGVPDQFGVH--------VKANLRRRRKRYTLTGKAWNNYHLTFSIQNYTEKLGWYNSMEAVRRAFQVWEQVTPLVFQEVSYDDIRLRRRAEADIMVLFASGFHGDSSPFDGVGGFLAHAYFPGPGLGGDTHFDADEPWTF--SSTDLHGISLFLVAVHELGHALGLEHSSNPSAIMAPFYQWMDTDNFQLPEDDLRGIQQLYGSPDGKPQPTRPLPTVRPRRPG---------------------------------------------------------------------------------------------------------------------------------------------------RPDHQPPRPPQPPHPGGKPERPPKPGPPPQ--PRATERPDQYGPNICDGNFDTVAVLRGEMFVFKGRWFWRVRHNRVLDNYPMPIGHFWRGLPG---NISAAYERQDGHFVFFKGNRYWLFREANLEPGYPQPLSSYGTDIPYDRIDTAIWWEPTGHTFFFQADRYWRFNEETQH-GDPGYPKPISVWQG-IPTSPKGAFLSNDAAYTYFYKGTKYWKFNNERLRME---PGHPKSILRDFMGCQEHVEP--------RSRWPDVARPPFNPNGGAEPEADGDSKEENAGD--------KDEGS---RVVVQMEEVVRTVNVVMVLVPLLLLLCILGLAFALV-QMQRKGAPRMLLYCKRSLQEWV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P51511-1", "uniprot_id": "MMP15_HUMAN", "id": "P51511-1", "name": "Matrix metalloproteinase-15", "aln": "MGSDPSAPGRPGWTGSLLGDREEAARPRLLPLLLVLLGCLGLGVAAEDAEVH-AENWLRLYGYLPQPSR--HMSTMRSAQILASALAEMQRFYGIPVTGVLDEETKEWMKRPRCGVPDQFGVR--------VKANLRRRRKRYALTGRKWNNHHLTFSIQNYTEKLGWYHSMEAVRRAFRVWEQATPLVFQEVPYEDIRLRRQKEADIMVLFASGFHGDSSPFDGTGGFLAHAYFPGPGLGGDTHFDADEPWTF--SSTDLHGNNLFLVAVHELGHALGLEHSSNPNAIMAPFYQWKDVDNFKLPEDDLRGIQQLYGTPDGQPQPTQPLPTVTPRRPG---------------------------------------------------------------------------------------------------------------------------------------------------RPDHRPPRPPQPPPPGGKPERPPKPGPPVQ--PRATERPDQYGPNICDGDFDTVAMLRGEMFVFKGRWFWRVRHNRVLDNYPMPIGHFWRGLPG---DISAAYERQDGRFVFFKGDRYWLFREANLEPGYPQPLTSYGLGIPYDRIDTAIWWEPTGHTFFFQEDRYWRFNEETQR-GDPGYPKPISVWQG-IPASPKGAFLSNDAAYTYFYKGTKYWKFDNERLRME---PGYPKSILRDFMGCQEHVEP--------GPRWPDVARPPFNPHGGAEPGADSAEGDVGDGDGDFGAGVNKDGGS---RVVVQMEEVARTVNVVMVLVPLLLLLCVLGLTYALV-QMQRKGAPRVLLYCKRSLQEWV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9P9J4-1", "uniprot_id": "A0A8M9P9J4_DANRE", "id": "A0A8M9P9J4-1", "name": "", "aln": "---MMAVLWDDPFTLLWR-------RTLVFSLLLLLMGARTFG-----DETFSGESWLRMYGYLPQASR--QMSTMRSAQILSNAISDMQRFYGLEITGEMDPGTIEAMKRPRCGVPDKFGAQ--------IKTNVRR--KRYALTGHKWDKTHITFSIQNYTPKIGEYNSYEAIRRAFRVWEKVTPLTFDEIPFHEVKYGRRKEPDIMIFFASGFHGDSSPFDGEGGFLAHAYFPGPGMGGDTHFDSDEPWTI--GSQNLQGNDLFLVAVHELGHALGLEHSNNPLAIMAPFYQWMDTENFELPEDDLRGVQQIYGPPS--SSPTQALPTVTPRRPA---------------------------------------------------------------------------------------------------------------------------------------------------HPDPRAPNPPKSP-PGAPPRRPDKP--------RTTDRPDHYGPNICEGNFDTVTMLRGEMFVFKGRWFWRVRRNRVLDNYPMPIGHFWRGLPG---DIDAAYERHDGRFVFFKGSQYWLFREANLESGYPQELMDYGRDIPYDKIDTAIWWEPSGFTYFFKGDWYWRFNEQDRA-ADQDYPKPISVWGTSVPSSPKGAFLSDDGAYTYFYKGAKYWKFDNHRMTSE---PGYPKSILRDFMGCNVDLDPDRDTDVDQGRKWPD--RPPFNPDAGRDKDKDKDKDKERDNTNDADSKEETEEKTNEVDVVLKIDETERTMNIIMVTVPLVLVLCILGLIYAIINTLQRKGAPKYLVYCRRSFQDWV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W122-1", "uniprot_id": "Q9W122_DROME", "id": "Q9W122-1", "name": "", "aln": "-----------MTN----------CQSSVFIVVGTLFSIMAAAQSAPVSTTTQAEIYLSQFGYLPASARNPASSGLHDQRTWVSAIEEFQSFAGLNITGELDAETMKLMSLPRCGVRDRVGTG--------DSR-----SKRYALQGSRWRVKNLTYKISKYPKRLKRVDVDAEIGRAFAVWSEDTDLTFTRK--------TSGPVHIEIKFVESEHGDGDAFDGQGGTLAHAFFP--VFGGDAHFDDAELWTI--GSP--RGTNLFQVAAHEFGHSLGLSHSDQSSALMAPFYRGFEP-VFKLDEDDKAAIQSLYGRKTNQLRPTNVYPATTQR-----------------------------------------------------------------------------------------------------------------------------------------------------------PYSPPKVPLDDSICK-------------------DSKVDTLFN-------SAQGETYAFKGDKYYKLTTDSVEEGYPQLISKGWPGLPG---NIDAAFTYKNGKTYFFKGTQYWRYQGRQMDGVYPKEISEGFTGIP-DHLDAAMVWGGNGKIYFFKGSKFWRFDPAKRPPVKASYPKPISNWEG-VPNNLDAALKYTN-GYTYFFKGDKYYRFHDARFAVDSATPPFPRPTAHWWFGCKNTPSS--------TGNIVEGSDNEFEQHSMIPHADDGNGDDFDAAVG--------DHQSN--DEPIVPEVAERTGNGAMSQSKLTSSSAVSTVITTILMCLVSKLIVS-------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8MPP3-1", "uniprot_id": "D2MP_DROME", "id": "Q8MPP3-1", "name": "Matrix metalloproteinase-2", "aln": "----MFSKYVLATLLALFAQSMCIQELSLPPEGSHSTAATRSKKAKTAISEDIMYNYLMQFDYLPKSDL--ETGALRTEDQLKEAIRSLQSFGNITVTGEIDSATARLIQKPRCGVGDRRSADSFSPDNLYHEIGSNVRVRRFALQGPKWSRTDLTWSMVN-RSMPDASKVERMVQTALDVWANHSKLTFREVY--------SDQADIQILFARRAHGDGYKFDGPGQVLAHAFYPGEGRGGDAHFDADETWNFDGESDDSHGTNFLNVALHELGHSLGLAHSAIPDAVMFPWYQ-NNEVAGNLPDDDRYGIQQLYGTKEKTWGPYKPQTTTTTTTTTTMRAMIYRADKPAYWPWNNPSNNPNNDRNRARERQEEERRRQEKERRRQEEERRHQEEERRRQVEERQRQEEERWRQEQERQEEENRRRKIEHKSQWERNPSKERNRPRERQEMERRRQEQERQEQERQEQEDRRRERERDRQLEWERRNRNGAREPVTPTANTTPRPTNKPYPTVHRQHHHHNKPRKPKPDSCMTYYDAISIIRGELFIFRGPYLWRIGTSGLYNGYPTEIRRHWSALPENLTKVDAVYENKQRQIVFFIGREYYVFNSVMLAPGFPKPLASLGLPPTLTHIDASFVWGHNNRTYMTSGTLYWRIDDYTGQ-VELDYPRDMSIWSG-VGYNIDAAFQYLD-GKTYFFKNLGYWEFNDDRMKVA---HARAKLSARRWMQCARSANEVD------------------------------------------------DEQRWTASLVSEGEETGRSGSRELRINHFILSILLLAIANWRS-----------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : :* :.*** . . :: .*: .:* * .: :** :* * :. ***** *: .. . :*::* * * .:*:.: : . : *: ** : : *.* . .* : *. ***. *** * ****::* ***:*** * *.: * :* .:: ** **:**:*** ** . *:* *:*: : :* :** .:*.:** * . .:. * * . . :** : *:* ::: . : :.** * : * .** .:.*.: :: : ** * .*: :. : :*: : . . ::*::: * .. :: . :**:: . .**: :* * : . ..*: : . ***:*. *:.*.: *: .: : :: * . : : . *: . : : : : ", "identical_positions": 109, "similar_positions": 147, "identity": "12.81%" }, { "cls_id": "homologset.agr.RGD:1308938", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4AAM0-1", "uniprot_id": "D4AAM0_RAT", "id": "D4AAM0-1", "name": "Transportin-3", "aln": "MEGAKPTLQLVYQAVQALYHDPDPSGKERASFWLGELQRSVHAWEISDQLLQIRQD----VESCYFAAQTMKMKIQTSFYELPTDSHASLRDSLLTHIQNLKDLSP-VIVTQLALAIADLALQMPSWKGCVQTLVEKYSNDVTSLPFLLEILTVLPEEVHSRSLRIGANRRTEIIEDLAFYSSTVVSLLMTCVEKAGTD------EKMLMKVFRCLGSWFNLGVLDSNFMANNKLLALLFEVLQQDKTSSNLHEAASDCVCSALYAIEN-----VETNLPLAMQLFQGVLTLETAYHMAVAREDLDKVLN-YCRIFTELCETFLEKIVCTPGQGLGDLRTLELLLICAGHPQYEVVEISFNFWYRLGEHLYKTNDEVIHSIFKAYIQRLLHALARHCQLEPDHEGVPEETDDFGEFRMRVSDLVKDLIFLIGSMECFAQLYSTLK---EGNPPWEVTEAVLFIMAAIAKSVDPENNPTLVEVLEGVVHLPETVHTAVRYTSIELVGEMSEVVDRNPQFLDPVLGYLMKGLCEKP-------LASAAAKAIHNICSVCRDHMAQHFNGLLEIAHSLDSFMLSPEAAVGLLKGTALVLARLPLDKITECLSELCSVQVMALKKLLSQE---PSNGISSDPTVFLDRLAVIFRHTNP--IVENGQTHPCQKVIQEIWPVLSETLNKH--RADNRIVERCCRCLRFAVRCVGKGSAALLQPLVTQMVNVYHVHQHSCFLYLGSILVDEYGMEE--GCRQGLLDMLQALCIPTFQLLEQ------QNGLQNHPDTVDDLFRLATRFIQRSPVTLLRS-QVVIPILQWAIAST-TLDHRDANSSVMRFLRDLIHTGVAND-------HEEDFEVRKELIGQVMDQLGQQLVSQLLHTCCFCLPPYTLPDVAEVLWEIMQVDR-PTFCRWLENSLKGLPKETTVGAVTVTHK-QLTDFHKQVTSAEECKQVCWALRDFTRLFR---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P2B1-1", "uniprot_id": "TNPO3_MOUSE", "id": "Q6P2B1-1", "name": "Transportin-3", "aln": "MEGAKPTLQLVYQAVQALYHDPDPSGKERASFWLGELQRSVHAWEISDQLLQIRQD----VESCYFAAQTMKMKIQTSFYELPTDSHASLRDSLLTHIQNLKDLSP-VIVTQLALAIADLALQMPSWKGCVQTLVEKYSNDVTSLPFLLEILTVLPEEVHSRSLRIGANRRTEIIEDLAFYSSTVVSLLMTCVEKAGTD------EKMLMKVFRCLGSWFNLGVLDSNFMANNKLLALLFEVLQQDKTSSNLHEAASDCVCSALYAIEN-----VETNLPLAMQLFQGVLTLETAYHMAVAREDLDKVLN-YCRIFTELCETFLEKIVCTPGQGLGDLRTLELLLICAGHPQYEVVEISFNFWYRLGEHLYKTNDEVIHSIFKAYIQRLLHALARHCQLEPDHEGVPEETDDFGEFRMRVSDLVKDLIFLIGSMECFAQLYSTLK---EGNPPWEVTEAVLFIMAAIAKSVDPENNPTLVEVLEGVVHLPETVHTAVRYTSIELVGEMSEVVDRNPQFLDPVLGYLMKGLCEKP-------LASAAAKAIHNICSVCRDHMAQHFNGLLEIAHSLDSFMLSPEAAVGLLKGTALVLARLPLDKITECLSELCSVQVMALKKLLSQE---PSNGISSDPTVFLDRLAVIFRHTNP--IVENGQTHPCQKVIQEIWPVLSETLNKH--RADNRIVERCCRCLRFAVRCVGKGSAALLQPLVTQMVNVYHVHQHSCFLYLGSILVDEYGMEE--GCRQGLLDMLQALCIPTFQLLEQ------QNGLQNHPDTVDDLFRLATRFIQRSPVTLLRS-QVVIPILQWAIAST-TLDHRDANSSVMRFLRDLIHTGVAND-------HEEDFELRKELIGQVMSQLGQQLVSQLLHTCCFCLPPYTLPDVAEVLWEIMQVDR-PTFCRWLENSLKGLPKETTVGAVTVTHK-QLTDFHKQVTSAEECKQVCWALRDFTRLFR---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y5L0-2", "uniprot_id": "TNPO3_HUMAN", "id": "Q9Y5L0-2", "name": "Transportin-3", "aln": "MEGAKPTLQLVYQAVQALYHDPDPSGKERASFWLGELQRSVHAWEISDQLLQIRQD----VESCYFAAQTMKMKIQTSFYELPTDSHASLRDSLLTHIQNLKDLSP-VIVTQLALAIADLALQMPSWKGCVQTLVEKYSNDVTSLPFLLEILTVLPEEVHSRSLRIGANRRTEIIEDLAFYSSTVVSLLMTCVEKAGTD------EKMLMKVFRCLGSWFNLGVLDSNFMANNKLLALLFEVLQQDKTSSNLHEAASDCVCSALYAIEN-----VETNLPLAMQLFQGVLTLETAYHMAVAREDLDKVLN-YCRIFTELCETFLEKIVCTPGQGLGDLRTLELLLICAGHPQYEVVEISFNFWYRLGEHLYKTNDEVIHGIFKAYIQRLLHALARHCQLEPDHEGVPEETDDFGEFRMRVSDLVKDLIFLIGSMECFAQLYSTLK---EGNPPWEVTEAVLFIMAAIAKSVDPENNPTLVEVLEGVVRLPETVHTAVRYTSIELVGEMSEVVDRNPQFLDPVLGYLMKGLCEKP-------LASAAAKAIHNICSVCRDHMAQHFNGLLEIARSLDSFLLSPEAAVGLLKGTALVLARLPLDKITECLSELCSVQVMALKKLLSQE---PSNGISSDPTVFLDRLAVIFRHTNP--IVENGQTHPCQKVIQEIWPVLSETLNKH--RADNRIVERCCRCLRFAVRCVGKGSAALLQPLVTQMVNVYHVHQHSCFLYLGSILVDEYGMEE--GCRQGLLDMLQALCIPTFQLLEQ------QNGLQNHPDTVDDLFRLATRFIQRSPVTLLRS-QVVIPILQWAIAST-TLDHRDANCSVMRFLRDLIHTGVAND-------HEEDFELRKELIGQVMNQLGQQLVSQLLHTCCFCLPPYTLPDVAEVLWEIMQVDR-PTFCRWLENSLKGLPKETTVGAVTVTHK-QLTDFHKQVTSAEECKQVCWALRDFTRLFR---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VQG0-1", "uniprot_id": "Q9VQG0_DROME", "id": "Q9VQG0-1", "name": "Transportin-3", "aln": "MD--TYSVDVVYQAISALFQGNNPKEQEKANKWLQDFQKSIYSWTIADELLHQKRD----LHANYFAAQTMRNKIQNSFSELPPHTHESLRDSLITHIGQIDEQTDNVIVTQLSLAVADLALLMASWREPINDLLVTLAPHQCAIWPLLEVLKVLPEEIDSRYLRLGANRREEVHKQLDASAECVLKFLCMCLQREDLDQ-----QRVWNAALRTYSAWLVIHAFPVSHVYNNALTQLAFRLLSLPETSGKLHDNATECVCALLSCINTRQDGASDPESSFEAQLFGAVCMLETPYHLSVAHEDTDKTIN-YCRIFTSLCDAFFYDLLADAQKPHYSLKGLDLVLLCVGHFDYEVAEITFHLWYKLSEDLFQRNEDKLTVLFRPHIERLISALFRHSQMESDHDGLIEENNNFFDFRRKVSDLIKDVAFIVGSGACFKQMFHILQ---APETTWESTEAALFIMQNVAKNILPDENEVIPKVVEAILNMSEQTHIAVRYTAILLIGELCDWIENHPESLEAVLNFLLYALQQKNG------LAPAAAIALTSICSACRQKMVCHISGLVEIARSLDSFQINNDVAIGLLKGISLILTRLPREQLQPALREIVGFQLQPLAQLVDSTGSTPQKGERTDPVYWIDRACAIIRHTNP--DVPDNVEHPTVAILNDAWQLISRVMDKY--QSDLRIMERTCRLIRYGIRMVRKQAMMLVEPLIKQMVVLYSVQHHSCFLYVGSILVDEFAKSS--ECIGGLLEMLQAFIEPTFGLLQM------ENGLKNNPDTVDDFFRLASRYLDCCPHQLLQS-SLITPIFQCALIAC-SLDHREANSSVMKFFINLLVWGRSNN-------HSRNTECR-PLVVELASQHGGALVMNLIQASVFQLHSYMLVDVAEVLHELKQVVGNERMQPFLAQALEALPKKNSGGYVTATQQ-QLDEFSSTVLRADTTKAISQALKTFTRLFR---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q99189-1", "uniprot_id": "MTR10_YEAST", "id": "Q99189-1", "name": "mRNA transport regulator MTR10", "aln": "--MDNLQVSDIETALQCISSTASQDDKNKALQFLEQFQRSTVAWSICNEILSKEDPTNALLELNIFAAQTLRNKVTYDLSQLENN-LPQFKDSLLTLLLSHN---QKLIITQLNVALARLAIQFLEWQNPIFEIISLLNSSPSILLNFLRILPEETLDIASTSLTEVEFN-SRIHELIDPIAEDVLKFLVSCIDLLQNTDGNSSSSISLEQILRCLNSWSYEFPVEQLLTVQPLINLVFETISNGNESDMEAFDSAIDCLCVILRESRDTTNEQLISALFHQLMLLQEKLLPTLFTDHPLNDEYDDDLLEGMTRLFVEAGEAWSVVISKNPD--FFKPMVLVLLMLTCKNEDLDVVSYTFPFWFNFKQSLVLPRYQESRKAYSDIFVKLINGIITHLQYPSGQFSSKEEEDKFKDFRYHMGDVLKDCTAVVGTSEALSQPLIRIKSAIENNNSWQIMEAPLFSLRTMAKEISLTENTILPEIIKIICNLPEQAK--IRYASTLVLGRYTEWTAKHPELLEVQLQYIFNGFQLHEGSSDMQSIITASSHALMFFCSDCSKLLVGYIDQLINFFLNVQS-SIDIESQFELCQGLSAVINNQPEAKVSVIFQKLVDDNLRQIEALIPQWK-ANPTLLAPQIADKIDLLYALFEELKPRYNYPQQGSEPLLPRIEFIWKALRTLLVDAGAMTDSIIVERVAKLLRRIFERFHVFCEPILPSVAEFLIQGYLTTGFGSYLWCSGSLIVIFGDDESFPISPSLKDAVWKFALSQCETFILNFNKFDKLQLNDYHEAIIDFFSLISDLIMFYPGAFLNSTELLGPVLNVALECVNKLDNYDAYICILRCLDDIISWGFKTPPISTVSIEIVPDEWRKQVINEVVIAHGNQLILVLFIGLVTTFENTAHSDAISCIVKCLRILTEANNNDATICIDWIYKVVEQLGQVTLNERDNLAKAVVEGLNSKDYRKVREGIRAFVGWYSRKNINSRFE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :. : *:..: . . :::* :* ::*:* :* *.:::* . :. *****:: *: .: :* . .::***:* : . . :*:*** :*:* **: : .*: : :: : :*.:* . :: * * . .: : : :. *:.:* *:: . :* .:* . : : : : . ::. : .: * :*:* * . . *: . .: * *. :: *:*.. ::: : . . * *::: : : :*.. :* :*:.: : * . : : : :*: .: * * ..: . ** :.* :** ::.*::** ::*: .: * :: : .*: ** ** : :**.: :* : :::: : .:.* .: :**:: ::*. : .:*: *: * ::: .: : : .*:: *: :** * . :. ::. *::: .::* :. : . * :* : :: . * :: : :: . :: : *: . . .: . :* .::.. :* : .* :: * : : . :* *:** .: :* .. . . :: .: :: * . ...:*: .. *: :. .. .* : : : . : : *:: ::: *:* * : : * :*.* .:: *::: *: . .**: :* .::: : ::: * . . * * :: :: * *: *: : *. . : : :: * ** ..: :* . :. : : .:: *. : ", "identical_positions": 128, "similar_positions": 331, "identity": "12.99%" }, { "cls_id": "homologset.agr.RGD:1308939", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9H2L4-1", "uniprot_id": "TMM60_HUMAN", "id": "Q9H2L4-1", "name": "Transmembrane protein 60", "aln": "MRMSLAQRVLLTWLFTLLFLIMLVLKLDEKAPWNWFLIFIPVWIFDTILLVLLIVKMAGRCKSGFDPRHGSHNIKKKAWYLIAMLLKLAFCLALCAKLEQFTTMNLSYVFIPLWALLAGALTELGYNVFFVRD---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8K174-1", "uniprot_id": "TMM60_MOUSE", "id": "Q8K174-1", "name": "Transmembrane protein 60", "aln": "MRMSLAQRVLLTWLFTLLFLIMLVLKLDEKAPWNWFLIFIPVWIFDTILLVMLIVKMAGRCKSGFDPRHGSHNIKKKAWYLIAMLLKLAFCLALCAKLEQFTTMNLSYVFIPLWALLAGALTELGYNVFFVRD---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZUD9-1", "uniprot_id": "D3ZUD9_RAT", "id": "D3ZUD9-1", "name": "", "aln": "MRMSLAQRVLLTWLFTLLFLIMLVLKLDEKAPWNWFLIFIPVWIFDTILLVMLIVKMAGRCKSGFDPRHGSHNIKKKAWYLIAMLLKLAFCLALCAKLEHFTTINLSYVFIPLWALLAGALTELGYNVFFVRD---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9W0B7-1", "uniprot_id": "Q9W0B7_DROME", "id": "Q9W0B7-1", "name": "Transmembrane protein 60", "aln": "--MTLAHRALFTWFIVLVFLILLCLRLDPRTTWNWFVTFTPLWFFDVIIIIYVIIKFIRKWRN---LTCLTDLLFLYKWNIAGVLLTIASQVMICLTLEYPQQIPIYVTVAPVILLLSTAIFYVGSRLGKREGWIQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:**:*.*:**::.*:***:* *:** ::.****: * *:*:**.*::: :*:*: : :. :. : * : .:**.:* : :* .** : : .. *: **: *: :* .: .. ", "identical_positions": 39, "similar_positions": 49, "identity": "28.68%" }, { "cls_id": "homologset.agr.RGD:1308940", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZSG3-1", "uniprot_id": "D3ZSG3_RAT", "id": "D3ZSG3-1", "name": "", "aln": "---------------------------------------------------------------------------------------MSSYQKELEKYRDIDEDEILRTLSPEELEQLDCELQEMDPENMLLPAGLRQRDQTKKSPTGPLDRDALLQYLEQQALEVKERDDLVPFTG-EKKGKPFIQP---KREIPAQEQITLEP--ELEEALSHATDAEMCDIAAILGMYTLMSNKQYYDAICSGEICNTEGISSVVQPDKYKPVPDEPPNPTNIEEMLKRVRSNDKELEEVNLNNIQDIPIPVLSDLCEAMKTNTYVRSFSLVATKSGDPIANAVADMLRENRSLLSLNIESNFISSTGLMAVLKAVRENATLTELRVDNQR-QWPGDAVEMEMATVLEQCPSIVRFGYHFTQQGPRARAANAMTRNNE-LRRQQKKR----------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JLH8-1", "uniprot_id": "TMOD4_MOUSE", "id": "Q9JLH8-1", "name": "Tropomodulin-4", "aln": "---------------------------------------------------------------------------------------MSSYQKELEKYRDIDEDEILRTLSPEELEQLDCELQEMDPENMLLPAGLRQRDQTKKSPTGPLDRDALLQYLEQQALEVKERDDLVPYTG-EKKGKPFIQP---KREIPAQEQITLEP--ELEEALSHATDAEMCDIAAILGMYTLMSNKQYYDAICSGEICNTEGISSVVQPDKYKPVPDEPPNPTNIEEMLKRVRSNDKELEEVNLNNIQDIPIPVLSDLCEAMKTNTYVRSFSLVATKSGDPIANAVADMLRENRSLQSLNIESNFISSTGLMAVLKAVRENATLTELRVDNQR-QWPGDAVEMEMATVLEQCPSIVRFGYHFTQQGPRARAAHAMTRNNE-LRRQQKKR----------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NZQ9-1", "uniprot_id": "TMOD4_HUMAN", "id": "Q9NZQ9-1", "name": "Tropomodulin-4", "aln": "---------------------------------------------------------------------------------------MSSYQKELEKYRDIDEDEILRTLSPEELEQLDCELQEMDPENMLLPAGLRQRDQTKKSPTGPLDREALLQYLEQQALEVKERDDLVPFTG-EKKGKPYIQP---KREIPAEEQITLEP--ELEEALAHATDAEMCDIAAILDMYTLMSNKQYYDALCSGEICNTEGISSVVQPDKYKPVPDEPPNPTNIEEILKRVRSNDKELEEVNLNNIQDIPIPMLSELCEAMKANTYVRSFSLVATRSGDPIANAVADMLRENRSLQSLNIESNFISSTGLMAVLKAVRENATLTELRVDNQR-QWPGDAVEMEMATVLEQCPSIVRFGYHFTQQGPRARAAQAMTRNNE-LRRQQKKR----------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4K6N4-1", "uniprot_id": "A0A0B4K6N4_DROME", "id": "A0A0B4K6N4-1", "name": "", "aln": "MSDIEDVFGGSAEETKPEPDAQSKTSVVTEHTEEVIPGETEKMVTETIDEDGDVVEETTEVTRKTVKRTMKITETSATTKTTTLTTPAKLYGKDLSEYDDVDVESLLAQLSPE---EITILAKEVDPDDNFLPPDQRNSYECTKEATGPLNRKQLIEHINKQAIETPDQPEFEPFVQGKVRGKKWVPPPRDARDIEAEEQIAIDMGEEYEHALNDATQEEIIDLAAILGFHSMMNQDQYHASLLNKGQPVGLGWDGITKSTQQKLFPMDPPNNTDVEESIKRVKDDDSKLIDLNLNNIKNISDEKLEQLFAALPQNEHLEVLSLTNVGLTDKTALLLAAAIEKSKTLRVLNVETNFISPPVIVKLVQALLKCHTIEEFRASNQRSAVLGNKIEMEITDLVEKNSSLLRLGLHLEFNDARHRVAAHLQRNIDRIFRVQKLKPNLPKLILPGNMEIERDLVAYNRSATPSPSPSPQPPVDYEVEEDPDNMVIRGGGDAFDPDVDPDNMVVPGSRSVTPNYDDEGVYQAHTWTSASHGPSDQELHRWRLAVGFIRLGLGSLHILHRKKSIAYQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * *:*.:* *:* :.:* **** :: :*:**:: :**.. *: : .*..****:*. *::::::**:*. :: :: *:. : :** :: * *:* *:***::: * *.** .**: *: *:****.::::*.:.**: :: . * ..:.:. : * .* :*** *::** :***:.:*.:* ::*****::*. *.:* *: * ::. :**. . * * :* :.:.::* **:*:****.. :: :::*: : *: *:*..*** *: :***:: ::*: .*::*:* *: :..* *.* : ** : : * ** : ", "identical_positions": 113, "similar_positions": 137, "identity": "19.82%" }, { "cls_id": "homologset.agr.RGD:1308941", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZX02-1", "uniprot_id": "D3ZX02_RAT", "id": "D3ZX02-1", "name": "Fascin", "aln": "MP--------TNG--LHQVLK---IQFGLVNDADRYLTAESFGFKVNASAASLKRKQIWVLEPDPGQGTAVLFRSSHLGRYLSAEEDGRVACEMDHPGRDCRFLVLPQPDG--RWVLQSEPHGRFFGGVEDRLSCFATAISPAELWTVHLAIHPQAHLLSVSRRRYVHLCLQEDEMAADGDMPWGVDALLTLIFQS---RRYCLKSYDSRYLRSDGRLVWEPEAHACYTLEFKAGKLAFKDCDGRYLAPVGPAGTLKAGRNTRPGKDELFDLEQSHPQVVLVA-ANHRYVSVRQGINVSANQDEELDHETFLMQIDQETKKCTFYSSTGGYWTLVTHGGIQATATQVSANTMFEIEWHG-RRVALKASNGRYVCMKKNGQLAAISDFVGEDELFILKLINRPILVLRGLDGFVCHRR-GSNQLDTNRSTYDVFHLS-FRDGAYQIRGRGGGFWYTGSHGSVCSDGDLAED-FLFEFRERGRLAIRALSGKYLRGGASGLLRADADLPTGEALWEY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q32M02-1", "uniprot_id": "FSCN2_MOUSE", "id": "Q32M02-1", "name": "Fascin-2", "aln": "MP--------TNG--LHQVLK---IQFGLVNDADRYLTAESFGFKVNASAASLKRKQIWVLEPDPGQGTAVLFRSSHLGRYLSAEEDGRVACEMDQPGRDCRFLVLPQPDG--RWVLQSEPHGRFFGGIEDRLSCFATAISPAELWTVHLAIHPQAHLLSVSRRRYVHLCLQEDEMAADGDMPWGVDALVTLIFQS---RRYCLKSYDSRYLRSDGRLVWEPEAHACYTLEFKAGKLAFKDCDGRYLAPVGPAGTLKAGRNTRPSKDELFDLEQSHPQVVLVA-ANRRYISVRQGINVSANQDEELGHETFLMQIDQETKKCTFYSSTGGYWTLVTHGGIQATATQVSANTMFEIEWHG-RRVALKASNGRFVCMKKNGQLAAISDFVGEDELFTLKLINRPLLVLRGLDGFVCHRR-GSNQLDTNRSTYDVFHLS-FRDGAYQIRGRGGGFWYTGSHGSVCSDGDLAED-FLFEFRERGRLAIRALSGKYLRGGASGLLRADADLPVGEALWEY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14926-1", "uniprot_id": "FSCN2_HUMAN", "id": "O14926-1", "name": "Fascin-2", "aln": "MP--------TNG--LHQVLK---IQFGLVNDTDRYLTAESFGFKVNASAPSLKRKQTWVLEPDPGQGTAVLLRSSHLGRYLSAEEDGRVACEAEQPGRDCRFLVLPQPDG--RWVLRSEPHGRFFGGTEDQLSCFATAVSPAELWTVHLAIHPQAHLLSVSRRRYVHLCPREDEMAADGDKPWGVDALLTLIFRS---RRYCLKSCDSRYLRSDGRLVWEPEPRACYTLEFKAGKLAFKDCDGHYLAPVGPAGTLKAGRNTRPGKDELFDLEESHPQVVLVA-ANHRYVSVRQGVNVSANQDDELDHETFLMQIDQETKKCTFYSSTGGYWTLVTHGGIHATATQVSANTMFEMEWRG-RRVALKASNGRYVCMKKNGQLAAISDFVGKDEEFTLKLINRPILVLRGLDGFVCHHR-GSNQLDTNRSVYDVFHLS-FSDGAYRIRGRDGGFWYTGSHGSVCSDGERAED-FVFEFRERGRLAIRARSGKYLRGGASGLLRADADAPAGTALWEY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6YWM1-1", "uniprot_id": "A0A8M6YWM1_DANRE", "id": "A0A8M6YWM1-1", "name": "Fascin", "aln": "MS--------TNG--ISAALK---LQFGLINHENRYLTAEAFGFKINASGNSMKKKQIWTLEQDPD--SQVVFLRSHLGRYLSSDKDGKVRCEEEVPNTDCRFLIVMQSDG--RWALQSEPYLRYFGGSEEYLSCFAQTIGESELWALHLALHPQANLLSVARKRYAHLSTQEDEISMDSNIPWGVDSLITLVYLE---GKYSLKTCDNRFLKNDGKLVMEHGPNTSFTLELKSGKLAFKDCEGKYLSPNGPTGTLKSGRCTRPGKDELFDLEESHPQVVFQA-ANKRYVSIRQGVCISANQDDETDMETFQMEIDKETKKCMFRTNGGNYWTLVTHGGILSSATEIEENTMFDIEWLG-RRIALKASNGKYVCTKKNGQLAAVSDSLGEDEQFVLKLINRPILVLRGENGFVCHHK-NSNTLHGSRSFYDIFTLL-FSDGGYQIKSGNQKFWYVSSSGLVCTDGDKPED-FFFEFVEYGRVGIKAQNGKYLRGDQGGTLMGDGLSVNASSLWEH", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24524-1", "uniprot_id": "SING_DROME", "id": "Q24524-1", "name": "Protein singed", "aln": "MNGQGCELGHSNGDIISQNQQKGWWTIGLINGQHKYMTAETFGFKLNANGASLKKKQLWTLEPSNT-GESIIYLRSHLNKYLSVDQFGNVLCESDERDAGSRFQISISEDGSGRWALKNESRGYFLGGTPDKLVCTAKTPGASEFWTVHLAARPQVNLRSIGRKRFAHLSESQDEIHVDANIPWGEDTLFTLEFRAEEGGRYALHTCNNKYLNANGKLQVVCNEDCLFSAEYHGGHLALRDRQGQYLSPIGSKAVLKS-RSSSVTRDELFSLEDSLPQASFIAGLNLRYVSVKQGVDVTANQDEVGENETFQLEYDWSAHRWALRTTQDRYWCLSAGGGIQATGNRRCADALFELIWHGDGSLSFRANNGKFLATKRSGHLFATSESIEEIAKFYFYLINRPILVLKCEQGFVGYRTPGNLKLECNKATYETILVERAQKGLVHLKAHSGKYWRIEGE-SISVDADAPSDGFFLELREPTRICIRSQQGKYLGATKNGAFKLLDDGTDSATQWEF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :** : : :**:* .:*:***:****:**.. *:*:** *.** . :: ***.:*** :: *.* ** : . ..** : . ** **.*:.*. ::** : * * * : . :*:*::*** :**.:* *:.*:*:.**. :**: *.: *** *:*.** : :*.*:: :.::*. :*:* :: * :.*:**::* :*:**:* *. ..**: * : :****.**:* **. : * * **:*::**: ::****: *** :: * .::: : :. . ** * : *** ::... :::*:: * * ::::*.**:::. *:.*:* * *: : : * : *****:***: :*** :: .. *. .:: *: : : .* :::. . :* . :. *.: ..* *.:*: * *: *:: .**** . .* : . : **.", "identical_positions": 158, "similar_positions": 174, "identity": "30.68%" }, { "cls_id": "homologset.agr.RGD:1308942", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q91YD1-1", "uniprot_id": "CXD3_MOUSE", "id": "Q91YD1-1", "name": "Gap junction delta-3 protein", "aln": "MGEWAFLGSLLDAVQLQSPLVGRLWLVIMLIFRILVLATVGGAVFEDEQEEFVCNTLQPGCRQTCYDRAFPVSHYRFWLFHILLLSAPPVLFVIYSMHQASKEAGGAQLAPPCARGRAEAPCSPCALRARRARRCYLLSVALRLLAELAFLGGQALLYGFRVDPHYACAGPPCPHTVDCFVSRPTEKTVFVVFYFAVGLLSALLSVAELGHLLWKGRQRA---------------KLLPPPPPSP---SLPSQRGDPDPFGPPAYAHRSPAGDSEGEGGSGHSKASLATVRQDLAI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E9PTP3-1", "uniprot_id": "E9PTP3_RAT", "id": "E9PTP3-1", "name": "Gap junction protein", "aln": "MGEWAFLGSLLDAVQLQSPLVGRLWLVIMLIFRILVLATVGGAVFEDEQEEFVCNTLQPGCRQTCYDRAFPVSHYRFWLFHILLLSAPPVLFVIYSMHQASKEAGGAQPAPPCARGRAEVPCSPCALRARRARRCYLLSVALRLLAELAFLGGQALLYGFRVAPHYACAGPPCPHTVDCFVSRPTEKTVFVVFYFAVGLLSALLSVAELGHLLWKGRQRA---------------KLLPPPPPSP---SLPSQRGDPDPFGPPAYAHRSPAGDSEGEGGSGHSKASLATVRQDLAI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N144-1", "uniprot_id": "CXD3_HUMAN", "id": "Q8N144-1", "name": "Gap junction delta-3 protein", "aln": "MGEWAFLGSLLDAVQLQSPLVGRLWLVVMLIFRILVLATVGGAVFEDEQEEFVCNTLQPGCRQTCYDRAFPVSHYRFWLFHILLLSAPPVLFVVYSMHRAGKEAGGAEAAAQCAPGLPEAQCAPCALRARRARRCYLLSVALRLLAELTFLGGQALLYGFRVAPHFACAGPPCPHTVDCFVSRPTEKTVFVLFYFAVGLLSALLSVAELGHLLWKGRPRAGERDNRCNRAHEEAQKLLPPPPPPPPPPALPSRRPGPEPCAPPAYAHPAPA--SLRECGSGRGKASPATGRRDLAI", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***************************:*****************************************************************:****:*.******: *. ** * .*. *:*************************:************* **:*************************:************************* ** ********.* :***:* .*:* .****** :** * * ***:.*** ** *:****", "identical_positions": 239, "similar_positions": 22, "identity": "80.74%" }, { "cls_id": "homologset.agr.RGD:1308943", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q3MIE4-1", "uniprot_id": "VAT1_RAT", "id": "Q3MIE4-1", "name": "NADPH-dependent quinone oxidoreductase VAT1", "aln": "MSAEREATEAATVAAAAEARAET----GAGEGAPSQPPT---VEVASDPQPPPAPEASASASAPP-----LRCLVLTGFGGYDKVKLQSRPAVPPAPGPGQVTLRVRACGLNFADLMGRQGLYDRLPPLPVTPGMEGAGVVVAVGEGVSDRKAGDRVMVLNRSGMWQEEVTVPSAQTFLMPEAMTFEEAAALLVNYITAYMVLFDFGNLRPGHSVLVHMAAGGVGMAALQLCRTVENVTVFGTASASKHEVLKENGVTHPIDYHTTDYVDEIKKISPKGVDIVMDPLGGSDTAKGYHLLKPMGKVVTYGMANLLTGPKRNLMAMARTWWNQFSVTALQLLQANRAVCGFHLGYLDGEVELVSRVVTHLLALYNQGHIKPRIDSVWPFEKVADAMRQMQEKKNIGKVLLVPGPEKET---------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62465-1", "uniprot_id": "VAT1_MOUSE", "id": "Q62465-1", "name": "NADPH-dependent quinone oxidoreductase VAT1", "aln": "MSAEREAAEAATVAAATEAGAETGT--GAGEGAPSQPPT---VEVASDPQPPPAPEASASASAPP-----LRCLVLTGFGGYDKVKLQSRPAVPPAPGPGQLTLRVRACGLNFADLMGRQGLYDRLPPLPVTPGMEGAGVVVAVGEGVGDRKAGDRVMVLNRSGMWQEEVTVPSAQTFLMPEAMTFEEAAALLVNYITAYMVLFDFGNLRPGHSVLVHMAAGGVGMAALQLCRTVENVTVFGTASASKHEVLKENGVTHPIDYHTTDYVDEIKKISPKGVDIVMDPLGGSDTAKGYHLLKPMGKVVTYGMANLLTGPKRNLMAMARTWWNQFSVTALQLLQANRAVCGFHLGYLDGEVELVNSVVTRLVALYNQGHIKPRIDSVWPFEKVADAMKQMQEKKNIGKVLLVPGPEKET---------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99536-1", "uniprot_id": "VAT1_HUMAN", "id": "Q99536-1", "name": "NADPH-dependent quinone oxidoreductase VAT1", "aln": "MSDEREVAEAAT-----------------GEDASSPPPK---TEAASDPQHPAASEGAAAAAASPP---LLRCLVLTGFGGYDKVKLQSRPAAPPAPGPGQLTLRLRACGLNFADLMARQGLYDRLPPLPVTPGMEGAGVVIAVGEGVSDRKAGDRVMVLNRSGMWQEEVTVPSVQTFLIPEAMTFEEAAALLVNYITAYMVLFDFGNLQPGHSVLVHMAAGGVGMAAVQLCRTVENVTVFGTASASKHEALKENGVTHPIDYHTTDYVDEIKKISPKGVDIVMDPLGGSDTAKGYNLLKPMGKVVTYGMANLLTGPKRNLMALARTWWNQFSVTALQLLQANRAVCGFHLGYLDGEVELVSGVVARLLALYNQGHIKPHIDSVWPFEKVADAMKQMQEKKNVGKVLLVPGPEKEN---------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8JFV8-1", "uniprot_id": "VAT1_DANRE", "id": "Q8JFV8-1", "name": "NADPH-dependent quinone oxidoreductase VAT1", "aln": "MSGEDAPAQQQNAEEQKQQETKTPAESPKTESKPDPPPTSASTEAAATAAAAADTPAPAAEKAPEEDTFTYRALVLTGYGGYDKVKLQVKKGKP-ALKSGEVMVRVKMCGLNFADLMARQGLYDRLPSPPVTPGMECSGVIEAVGEEVTDRKVGDKVLVLNRSGMWQEVVVVASTHTFLMPEGMSFEEAAALPVNYITAYMMLFDFGHLRPNQSVLVHMAAGGVGIAATQLCKTVNDVTVFGTASASKHEVISQGGVTHPIDYRTRDYVEEVRKISPKGLDIVLDPLGGSDTHKGYNLLKPMGKLISYGAANMLAGQKKNLFAVAKTWYQQFSVHTLSLIQGNRSVCGFHLGYLDSETELIDQAMTAVMDLYRQGKVKPRIDSTYHLEQVGDAMRRMQERNNIGKIILTTEPMKEEEKKEEAKKDEEKKDDKKKDDKKKDDKKKEDKKKDEAKKEEKKDEKKKEEAKKDDKKAEEKKEEVKKEEN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** * :: . *. .. **. .*.*: . .. . ..*: *. *.*****:********* : . * * .*:: :*:: *********.*********. ******* :**: **** * ***.**:*:********** *.*.*.:***:**.*:******* ********:*****:*:*.:************:** ***:**::*************.:.:.********:* ***:*::******:***:******** ***:*******:::** **:*:* *:**:*:*:**::**** :*.*:*.**:**********.*.**:. .:: :: **.**::**:***.: :*:*.***::***::*:**::*.. * ** ", "identical_positions": 239, "similar_positions": 106, "identity": "49.28%" }, { "cls_id": "homologset.agr.RGD:1308944", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AVU1-1", "uniprot_id": "A0A8I6AVU1_RAT", "id": "A0A8I6AVU1-1", "name": "", "aln": "-----------------------------------------------MEGVELKEEWQDEDFPIP-----------------LPEDDSIEADILDVTDPDRQPGSLEVNG---------------------------------NKVRKKLVAPDISLTLDPGEDSLWSD-----------------------------------------------------DLDEGGEVDLDGLDTPSENSDEFEWEDD---------------------------LPKP-KTTEVIRKGSITEYAATEEKEDGRRWRMFRIGE-QDHRVDMKAIEPYKKVISHGGYYGDG-LNAIVVFAVCFMPESGQPNYRYLMDNLFKYVIGTLELLVAENYMIIYLNGATTRRKMPSLGWLRRCYQQIDRRLRKNLKSLIIVHPSWFIRTLLAVTRPFISSKFSQKIRYVFNLAELAELVPMEYVGIPECIKQ------------VDQELNGKQEPPKSEQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54940-1", "uniprot_id": "BNIP2_MOUSE", "id": "O54940-1", "name": "BCL2/adenovirus E1B 19 kDa protein-interacting protein 2", "aln": "-----------------------------------------------MEGVELKEEWQDEDFPIP-----------------LPEDDSIEADTLDGTDPDRQPGSLEVNG---------------------------------NKVRKKLMAPDISLTLDPGEDSLWSD-----------------------------------------------------DLDEAGEVDLEGLDTPSENSDEFEWEDD---------------------------LPKP-KTTEVIRKGSITEYTATEEKGDGRRWRMFRIGE-QDHRVDMKAIEPYKKVISHGGYYGDG-LNAIVVFAVCFMPESGQPNYRYLMDNLFKYVIGTLELLVAENYMIIYLNGATTRRKMPSLGWLRRCYQQIDRRLRKNLKSLIIVHPSWFIRTLLAVTRPFISSKFSQKIRYVFNLAELAELVPMEYVGIPECIKQYEEEKFKKRQKRVDQELNGKQEPPKSEQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q12982-1", "uniprot_id": "BNIP2_HUMAN", "id": "Q12982-1", "name": "BCL2/adenovirus E1B 19 kDa protein-interacting protein 2", "aln": "-----------------------------------------------MEGVELKEEWQDEDFPIP-----------------LPEDDSIEADILAITGPEDQPGSLEVNG---------------------------------NKVRKKLMAPDISLTLDPSDGSVLSD-----------------------------------------------------DLDESGEIDLDGLDTPSENSNEFEWEDD---------------------------LPKP-KTTEVIRKGSITEYTAAEEKEDGRRWRMFRIGE-QDHRVDMKAIEPYKKVISHGGYYGDG-LNAIVVFAVCFMPESSQPNYRYLMDNLFKYVIGTLELLVAENYMIVYLNGATTRRKMPSLGWLRKCYQQIDRRLRKNLKSLIIVHPSWFIRTLLAVTRPFISSKFSQKIRYVFNLAELAELVPMEYVGIPECIKQ------------VDQELNGKQDEPKNEQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VZJ4-1", "uniprot_id": "Q9VZJ4_DROME", "id": "Q9VZJ4-1", "name": "CRAL-TRIO domain-containing protein", "aln": "MSLHYAESESSPSESKMDISETPTDSTGVSPLADDVLPTAPEKNILKLEQAKQDHDKEELEFKTTSALDNRILRPELLPMEAMPQRHNIIERTLANSHPLMSPTNTDSDSEPFQLKKQEKQLPRSNFPDVVPTTETVQVKNNLNQCRNKPQDAKVSLLRANSPDILSSESDADVSQYLAAVESNFQSVSLMPNGNGKKSKRSTALPGGEDISSLDSISNHSFDDDEDIEHNLASLSPSSSLIDGLDGEDDDDDCEGPELLPDHDDDLELDLEFGLATTPTPNAPASATAASTLPQYTAAEERRDSRNWQKITLPDGRTREIDMRVIEPYKRVLSHGGYLKSGGQNAIVIFCACHLPDRSRADYSYVMDNLFLYVVKTLEQLVTDDYVLIYLHGGSNRRNVPPFPWLKRCYQLLDRRLRKSLKHMYLVHPTFWIKSLVWMARPFVSTKFWRKLVYVKSLEELGMHVVVEKAAIPEKVKQ----------------YDAKRH------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* .: ..: :: :* . :*: ..* * : * .* . : :. *: *:* ..:** . . : *: * ** * :* .*...*. : :: *** *.* .:.. .::.:*:*:**: *.*.*: : : : : :.:**:.*****:*:***** .* ****:*..*.:*: .:.:* *:***** **: *** **:::*:::**:*.:.**::*.: **::*** :******.** : :***:::*::*: ::***:*:** :*: ** .* **. * :* ..*** :** :.*:. ", "identical_positions": 112, "similar_positions": 120, "identity": "22.13%" }, { "cls_id": "homologset.agr.RGD:1308945", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9H9S4-1", "uniprot_id": "CB39L_HUMAN", "id": "Q9H9S4-1", "name": "Calcium-binding protein 39-like", "aln": "---------MKKMPLFSKSHKNPAEIVKILKDNLAILEK---QDKKTDKASEEVSKSLQAMKEILCGTNEKEPPTE-AVAQLAQELYSSGLLVTLIADLQLIDFEGKKDVTQIFNNILRRQIGTRSPTVEYISAHPHILFMLLKGYEA-------PQIALRCGIMLRECIRHEPLAKIILFSNQFRDFFKYVELSTFDIASDAFATFKDLLTRHKVLVADFLEQNYDTIF---EDYEKLLQSENYVTKRQSLKLLGELILDRHNFAIMTKYISKPENLKLMMNLLRDKSPNIQFEAFHVFKVFVASPHKTQPIVEILLKNQPKLIEFLSSFQKERTDDEQFADEKNYLIKQIRDLKKTAP-----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DB16-1", "uniprot_id": "CB39L_MOUSE", "id": "Q9DB16-1", "name": "Calcium-binding protein 39-like", "aln": "---------MKKMPLFSKSHKNPAEIVKILKDNLAILEK---QDKKTDKASEEVSKSLQAMKEILCGTNDKEPPTE-AVAQLAQELYSSGLLVTLIADLQLIDFEGKKDVTQIFNNILRRQIGTRCPTVEYISSHPHILFMLLKGYEA-------PQIALRCGIMLRECIRHEPLAKIILFSNQFRDFFKYVELSTFDIASDAFATFKDLLTRHKVLVADFLEQNYDTIF---EDYEKLLQSENYVTKRQSLKLLGELILDRHNFTIMTKYISKPENLKLMMNLLRDKSPNIQFEAFHVFKVFVASPHKTQPIVEILLKNQPKLIEFLSSFQKERTDDEQFADEKNYLIKQIRDLKKAAP-----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5XIJ7-1", "uniprot_id": "Q5XIJ7_RAT", "id": "Q5XIJ7-1", "name": "", "aln": "---------MKKMPLFSKSHKNPAEIVKILKDNLAILEK---QDKKTDKASEEVSKSLQAMKELLCGAQDKEPPTE-AVAQLAQELYSSGLLVTLIADLQLIDFEGKKDVTQIFNNILRRQIGTRCPTVEYICSHPHILFMLLKGYEA-------PQIALRCGIMLRECIRHEPLAKVILFSNQFRDFFKYVELSTFDIASDAFATFKDLLTRHKVLVADFLEQNYDTIF---EDYEKLLQSENYVTKRQSLKLLGELILDRHNFTIMTKYISKPENLKLMMNLLRDKSPNIQFEAFHVFKVFVASPHKTQPIVEILLKNQPKLIEFLSSFQKERTDDEQFADEKNYLIKQIRDLKKAAP-----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P91891-1", "uniprot_id": "MO25_DROME", "id": "P91891-1", "name": "Protein Mo25", "aln": "------------MPLFGKSQKSPVELVKSLKEAINALEA---GDRKVEKAQEDVSKNLVSIKNMLYGSSDAEPPADYVVAQLSQELYNSNLLLLLIQNLHRIDFEGKKHVALIFNNVLRRQIGTRSPTVEYICTKPEILFTLMAGYEDAH-----PEIALNSGTMLRECARYEALAKIMLHSDEFFKFFRYVEVSTFDIASDAFSTFKELLTRHKLLCAEFLDANYDKFFS--QHYQRLLNSENYVTRRQSLKLLGELLLDRHNFTVMTRYISEPENLKLMMNMLKEKSRNIQFEAFHVFKVFVANPNKPKPILDILLRNQTKLVDFLTNFHTDRSEDEQFNDEKAYLIKQIKELKPLPEA----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32464-1", "uniprot_id": "HYM1_YEAST", "id": "P32464-1", "name": "Protein HYM1", "aln": "MFKKYKNQDLDMAFWWKKNPKTPSDYARLIIEQLNKFSSPSLTQDNKRKVQEECTKYLIGTKHFIVGDTDPHPTPE-AIDELYTAMHRADVFYELLLHFVDLEFEARRECMLIFSICLGYSKDNKFVTVDYLVSQPKTISLMLRTAEVALQQKGCQDIFLTVGNMIIECIKYEQLCRIILKDPQLWKFFEFAKLGNFEISTESLQILSAAFTAHPKLVSKEFFSNEINIIRFIKCINKLMAHGSYVTKRQSTKLLASLIVIRSNNALMNIYINSPENLKLIMTLMTDKSKNLQLEAFNVFKVMVANPRKSKPVFDILVKNRDKLLTYFKTFGLD-SQDSTFLDEREFIVQEIDSLPRIISSTTEVSNNNASSSNVASITSPSSVMNNQSSILTHSTSPDSR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *. *.* : .: : : : :. : : *..*: :* * . *.:: * : .*..: .: :* :: :.:: *: .: ::**.::. **. * . ..: **:*: ::*. : :: * :* * * *: ** ::* *.:::* . :: .**.:.::..*:*::::: :. :* * * :. : * .:: : ::*: .***:*** ***..*:: * * ::*. **..******:*.:: :** *:*:***:****:**.*.*.:*:.:**::*: **: ::..* : ::*. * **: :::::* .* ", "identical_positions": 90, "similar_positions": 141, "identity": "22.44%" }, { "cls_id": "homologset.agr.RGD:1308946", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D8V0-1", "uniprot_id": "SPP_MOUSE", "id": "Q9D8V0-1", "name": "Signal peptide peptidase", "aln": "------------------------------------------MDSAVSDPHNGSAE-AGTPANGTT---RPPSTPEGIALAYGSLLLMALLPIFFGALRSVR------------------------------------CARGKSSS-DMPETITSRDAARFPIIASCTLLGLYLFFKIFSQEYINLLLSMYFFVLGILALSH---TISPFMNKFFP---------ANFPNRQYQLLFTQGSG---------------------------------------------------ENKEEIINYEFDTKDLVCLGLSSVVGVWYLLR-KHWIANNLFGLAFSLNGVELLHLNNVSTGCILLGGLFIYDIFWVFGTNVMVTVAKSFEAPIKLVFPQDLLEKGLEADNFAMLGLGDIVIPGIFIALLLRFDISLKKNTH--------------TYFYTSFAAYIFGLGLTIFIMHIFKHAQPALLYLVPACIGFPVLVALAKGEVAEMF--SYEESNPKDP-AAETESKEESTEASASKRLE-KKEK---------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZP98-1", "uniprot_id": "D3ZP98_RAT", "id": "D3ZP98-1", "name": "", "aln": "------------------------------------------MDSALSDPHNGSSE-AGTPANGTT---RPPSTPEGIALAYGSLLLMALLPIFFGALRSVR------------------------------------CARGKSSS-DMPETITSRDAARFPIIASCTLLGLYLFFKLFSQEYINLLLSMYFFVLGILALSH---TISPFMNKFFP---------ANFPNRQYQLLFTQGSG---------------------------------------------------ENKEEIINYEFDTKDLVCLGLSSVVGVWYLLR-KHWIANNLFGLAFSLNGVELLHLNNVSTGCILLGGLFIYDIFWVFGTNVMVTVAKSFEAPIKLVFPQDLLEKGLEADNFAMLGLGDIVIPGIFIALLLRFDISLKKNTH--------------TYFYTSFAAYIFGLGLTIFIMHIFKHAQPALLYLVPACIGFPVLVALVKGEVAEMF--SYEESNPKDP-AAVTESKEESTEASASKRLE-KKEK---------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8TCT9-1", "uniprot_id": "SPP_HUMAN", "id": "Q8TCT9-1", "name": "Signal peptide peptidase", "aln": "------------------------------------------MDSALSDPHNGSAE-AGGPTNSTT---RPPSTPEGIALAYGSLLLMALLPIFFGALRSVR------------------------------------CARGKNAS-DMPETITSRDAARFPIIASCTLLGLYLFFKIFSQEYINLLLSMYFFVLGILALSH---TISPFMNKFFP---------ASFPNRQYQLLFTQGSG---------------------------------------------------ENKEEIINYEFDTKDLVCLGLSSIVGVWYLLR-KHWIANNLFGLAFSLNGVELLHLNNVSTGCILLGGLFIYDVFWVFGTNVMVTVAKSFEAPIKLVFPQDLLEKGLEANNFAMLGLGDVVIPGIFIALLLRFDISLKKNTH--------------TYFYTSFAAYIFGLGLTIFIMHIFKHAQPALLYLVPACIGFPVLVALAKGEVTEMF--SYEESNPKDP-AAVTESKE-GTEASASKGLE-KKEK---------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VPQ7-1", "uniprot_id": "SPP_DROME", "id": "Q9VPQ7-1", "name": "Signal peptide peptidase", "aln": "--------------------------------------MAEEVIGTVKEVLKGIIENVNAPKNESAPGEKKPSTPEGMAVAYSSLVVMAMLPIIFGSIRSVK------------------------------------LHKLKKSTGEKADTMTKKDAMYFPLIASAALFGLYLFFKIFQKVHINYLLTGYFFVLGVIALAH---LLSPVINSLMP---------AAVPKVPFHILFTKGEG---------------------------------------------------KHKEDIVNYKFSTHDIVCLVISSAIGVWYLLK-KHWIANNLFGLAFAINGVEMLHLNNFVTGVILLSGLFFYDIFWVFGTNVMVTVAKSFEAPIKLVFPQDLIENGLNASNFAMLGLGDIVIPGIFIALLLRFDDSKKRKTR--------------IYFYSTLIAYFLGLLATIFVMHVFKHAQPALLYLVPACMGTPLLVALIRGELKVLF--AYEDHPEEKPEKKEKKEKDEGVSSSGSKKKESKKGK---------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P34248-1", "uniprot_id": "SPP_YEAST", "id": "P34248-1", "name": "Intramembrane protease YPF1", "aln": "MDKYLNSFVDHLSEWSSRAFRNNSSSANQSASNKELEQVFEQINAIVENHNNKLTTAFDKISYRVAHKITHLVESHSLVFNYATLVLIASALVVIGSFTSISSIPFTALPPTREHSLFDPTDFDVDHDCHVIYRENDEDKKKKKKSKRFFDMMDEKHAIILPLTSGCTLLALYFVIKKLHLNWLKYVVKILNFNITLLNIPAGTFVYSYFLNSLFRNLSHLASWNPLVVLPRYRVTIADDNEDLNKIGGFVTNLNYKDGLTNSVVHKKTLDEIEKDHWMKHFYRRELVEPKDIKSKRQISNMYLNSALIVSFVLSIVSTVYFYLSPNDWLISNAVSMNMAIWSIAQLKLKNLKSGALILIALFFYDICFVFGTDVMVTVATNLDIPVKLSLPVKFNTAQNNFN-FSILGLGDIALPGMFIAMCYKYDIWKWHLDHDDTEFHFLNWSYVGKYFITAMVSYVASLVSAMVSLSIFNTAQPALLYIVPSLLISTILVACWNKDFKQFWNFQYDTIEVDKSLKKAIEKKENSITYSTFILSEYYNDADKYALLGDDVNENFDDDEEFVQEEDLSDSSEEELSEEDLLDDESS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . :.: : . : ...:.. *.:*:::* :.:*:: *: : *. : : : .:.* :*: :..:*:.**:.:* : :: ::. * : :: :. * .:*.:: . . ::: ::... : *.:* * :.: :*.: :* *:: * :.*: .* ..: ::: .: *:*:*. :* ::* .**:**: :****:******..:: *:** :* .: : . *::*****:.:**:***: ::* : : ** ::: :*. .* ::. : :*: *******:**: : .:*** . :. :: *: ... :.*: . * * : ", "identical_positions": 80, "similar_positions": 157, "identity": "13.61%" }, { "cls_id": "homologset.agr.RGD:1308947", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZS31-1", "uniprot_id": "D3ZS31_RAT", "id": "D3ZS31-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------MEEKSVGEPTQVVSKVKLSTKVENPGHWLVDDHARIWEVLKTEES----SIQDWGEEVEEGAVYHVTLKRVQIQQAANKGARWLGVEGDQLPPGHTVSQYETCKIRTIKAGTLEKLVENLLTAFGDNDFTYISIFLSTYRGFASTKEVLELLLDRYGNLTGPHWEDDGSQSSP------------ESKAVIRNAIASILRAWLDQCAEDFREPPHFPCLQKLLEYLKQMMPGSDPERRAQNLLEQFQKQ---DVDSDNG--------------LLNTISFSPEEEEELESGGSAELT--------------------------TFSEDLVAEQLTYMDAQLFKKVVPHHCLGCVWSRRDRKENKHLAPTIRATISQFNALTKCVVSTILGSKDLKTQQRARVIEKWINIAHECRILKNFSSLRAIVSALQSNSIYRLKKAWAAVPKDRMLMFEELSEIFSDHNNHLTSRELLMKEGTSKFANLDSSVKENQKRTQRRLQLQKDMGVMQGTVPYLGTFLTDLTMLDTALQDYIEG-GLINFEKRRREFEVIAQIKLLQSACNSYCMSPDQKFIQWFQRQQLLTEEESYALSCEIEAAADASTTSPKPRKSMVKRLSLLFLGSDLIPGSTPTKEQPKSTASGSSGESMDSVSVSSCESNHSEAEEGSATPMDTPDEPQKKLSESSSSCSSIHS-MDTNSSGMSSLINPLSSPPACNNNPKMHKRSVSVT---SITSTVLPPVYNQQNEDTCIIRISVEDNNGNMYKSIMLTSQDKTPAVIQRAMSKHNLESDPAEEYELVQVISEDKELVIPDSANVFYAMNSQVNFDFILRKKSSVEEQVKMRSRTSLTMPRTAKRGCWSNRHSKVTL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60695-1", "uniprot_id": "RGL1_MOUSE", "id": "Q60695-1", "name": "Ral guanine nucleotide dissociation stimulator-like 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKLLWQAKMS----SIQDWGEEVEEGAVYHVTLKRVQIQQAANKGARWLGVEGDQLPPGHTVSQYETCKIRTIKAGTLEKLVENLLTAFGDNDFTYISIFLSTYRGFASTKEVLELLLDRYGNLTGPNCEDDGSQSSP------------ESKAVIRNAIASILRAWLDQCAEDFREPPHFPCLQKLLEYLKQMMPGSDPERRAQNLLEQFQKQ---DVDSDNG--------------LLNTSSFSLEEEEELESGGSAEFT--------------------------NFSEDLVAEQLTYMDAQLFKKVVPHHCLGCIWSQRDKKENKHLAPTIRATISQFNTLTKCVVSTVLGSKELKTQQRARVIEKWINIAHECRILKNFSSLRAIVSALQSNSIYRLKKAWAAVPKDRMLMFEELSDIFSDHNNHLTSRELLMKEGTSKFANLDSSVKENQKRTQRRLQLQKDMGVMQGTVPYLGTFLTDLTMLDTALQDYIEG-GLINFEKRRREFEVIAQIKLLQSACNSYCMGPDQKFIQWFQRQQLLSEEESYALSCEIEAAADANTTSPKPRKSMVKRLSLLFLGSDIIPGSTPTKEQPKSAASGSSGESMDSVSVSSCESNHSEAEEGPVTPMDTPDEPQKKLSESSSSCSSIHS-MDTNSSGMSSLINPLSSPPTCNNNPKIHKRSVSVT---SITSTVLPPVYNQQNEDTCIIRISVEDNNGNMYKSIMLTSQDKTPAVIQRAMSKHNLESDPAEEYELVQVISEDKELVIPDSANVFYAMNSQVNFDFILRKKNSVEEQVKLRSRTSLTLPRTAKRGCWSNRHSKITL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NZL6-1", "uniprot_id": "RGL1_HUMAN", "id": "Q9NZL6-1", "name": "Ral guanine nucleotide dissociation stimulator-like 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKLLWQAKMS----SIQDWGEEVEEGAVYHVTLKRVQIQQAANKGARWLGVEGDQLPPGHTVSQYETCKIRTIKAGTLEKLVENLLTAFGDNDFTYISIFLSTYRGFASTKEVLELLLDRYGNLTSPNCEEDGSQSSS------------ESKMVIRNAIASILRAWLDQCAEDFREPPHFPCLQKLLDYLTRMMPGSDPERRAQNLLEQFQKQ---EVETDNG--------------LPNTISFSLEEEEELEGGESAEFT--------------------------CFSEDLVAEQLTYMDAQLFKKVVPHHCLGCIWSRRDKKENKHLAPTIRATISQFNTLTKCVVSTILGGKELKTQQRAKIIEKWINIAHECRLLKNFSSLRAIVSALQSNSIYRLKKTWAAVPRDRMLMFEELSDIFSDHNNHLTSRELLMKEGTSKFANLDSSVKENQKRTQRRLQLQKDMGVMQGTVPYLGTFLTDLTMLDTALQDYIEG-GLINFEKRRREFEVIAQIKLLQSACNSYCMTPDQKFIQWFQRQQLLTEEESYALSCEIEAAADASTTSPKPRKSMVKRLSLLFLGSDMITSPTPTKEQPKSTASGSSGESMDSVSVSSCESNHSEAEEGSITPMDTPDEPQKKLSESSSSCSSIHS-MDTNSSGMSSLINPLSSPPSCNNNPKIHKRSVSVT---SITSTVLPPVYNQQNEDTCIIRISVEDNNGNMYKSIMLTSQDKTPAVIQRAMLKHNLDSDPAEEYELVQVISEDKELVIPDSANVFYAMNSQVNFDFILRKKNSMEEQVKLRSRTSLTLPRTAKRGCWSNRHSKITL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6P112-1", "uniprot_id": "RGL1_DANRE", "id": "Q6P112-1", "name": "Ral guanine nucleotide dissociation stimulator-like 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------MISHYPLASLLPWPPVPQLLDIDGDGGVALQRYQPRSPETGPRYWS----SVQDWGEEVEEGAIYNVTLKRVQIQQAANKGARWLGAEGDRLPPGHTVSQLETCKIRSIRAGTLERLVETLLTAFGDNDLTYTSIFLSTYRAFASTQSVLELLLDRYG--SFEDCEGERSQCQTG-----------ESRKAVRKALASILRAWLDQCPEDFQEPPSYPSLHRVLGFLQKAMPGSEPMRRAQSLLEQLRVQASLENETEGG--------------FQCINPFCLGEDEEVEIDLQEDFF--------------------------SFEVDLVAEQLTYMDALLFKKVVPHHCLGSIWSQRDKKDGKQSAPTIRATITQFNAVTACVVSTILRQRQIRPHLCARIIQRWIDIAQECRIRKNFSSLRAIVSALQSNPLYRLKRTWASVAKDSMQMFEELSDIFSDQNNYLTSRELLMREGTSKFASLDSCAKDHQKRSQKRLQLQKDMGAMQGTIPYLGTFLTDLTMLDTALPDQVEG-GLINFEKRRREFEVIAQIKLLQSACNSYCLTPDPAFFRWFKSQPQYSEEESYVLSCEVEGLGDNSPTSPKPRKSMVKRLSLLFLGNDSTNTSSPVRESPRSPPTGSSGESMDSVSVSSSDSSPSESD--GMTPTHSIDAHLKKLSESSS-CNSLHS-MDTSSSTASASISLAS--PTLPGPPCNHRRSISLTPLMSPTSPGFPPAYNTQAQDACIIRVSLEQGNGNLYKSIMLTSQDKTPAVISRAMTKHNLEGEQAADYELVQVISEERELVIPDNANVFYAMSTSANFDFLLRLRGSEGRPVQLRSRCSSTLPRTQQRSSLSLRLSKVTL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9PCE9-1", "uniprot_id": "M9PCE9_DROME", "id": "M9PCE9-1", "name": "", "aln": "MNFTSRANCKCPHSQKHQQKPALIKSHTCAYQLQDLTGYNRALMPPLDNTDFSNAWRQVNNNTTSQSCAYHQQRQQQQQQQDAKDSKRHYHHHTCPRQRKKSMTPVEPTHLCQKHQEAKQRRSRSASAKPRRNSSYHSYDDLDVSSAVLNAERKVVASLKYLCACTGATLRNLSKKTKDLHAKNYTYTKPTWRLWGEEHEKNAIFTVYLKKVRYHRPTPTAS-------NDSDDEISHLEWETVRVRFVKAATLARLVEALATDDGELESTFINVFLSTYRTFSTPKQVLSLLTQRYDALHEKHLEELEQAQQNGQVMDPAYDPHASIHEQHKKTLVSALHVWLDGFPEDWHEDN----LQQILAFATKRLKRSDLHIKVLNRLERLIKQSLYGNGGGSGGSENNGHSWLSAARSQQMQQFMIPTHYGSSYDLTDQFNGMYLSPMGHGPIYRGPTHFLQAFRFPHVPVRHFAEQLTRMDTELFKRLIPHQCLGHTWARRDSGGSE----TVVATINQFNAVLFRVVSSILIDR-LKPQERALNISRWIDIAQELRMLKNFSSLKAIISALNSNSIYRLSKIWEVLPKERMEVFTELANICSEDNNAWTLREVLKREGTAKNPDPGS---DHSDRHLQKLILNLGTQTSHGTIPYLGTFLTDLTMIHTANPDYLTENKLINFDKKRKEFEVLAQIKLLQGAANTYNLQADALFDHWFNSMPVFDEREAFELSCRLEPPPPAPRKSVVSTNTSLTNTTASSTASIMGHRKTDSIHSNSSSGAGSQFYCELNSSTSSRHNSLDRDVHHQHASLMSASSSVSNLSLDSSNSGGRQSGKLTHSQSMGNGLKSHGNGTTNGGSPHINAQLVQPS---SGTPHSAPDFYIIR---VTYETDNIELDGIVLYKSIMLGNNERTPQVIRNAMLKLGLEDD-PDRFTLAQVLP-DKELVMPKNANVYYAVNTNYNLNFILRPRKEEGVAGSX-----STAVPLSQLWCLGYEGEE---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : **** *:.*:: * **:*: ::.: ..: : : : ** ::* ::*.** :*** * * *: : *: .:****** *::.:.**.** :**. . * . . . : ::::.* *:.*** .**::* *:::* : : : *: :. . **:: * .* * . . . :: . .***** **: ***:::**:*** *::** .: *: ***.***:: ***::* : ::.: * *.:**:**:* *: ******:**:***:**.:***.: * :.:: * :* **::* *:.** * **:* :***:* .. .* ::..* ::* *: . . :**:************:.** * : ****:*:*:****:*******.*.*:* : .* * :**: *.*:: ***.:* .* . :: :.. : .. : .. *. :**. . . *.** ... .. :. : . .:** .** ... :* * *. . :. . .: . * : : :. : * *. * * : . .:* .. :****** .:::** ** .** * .*:.: . : *.**:. ::***:*..***:**:.:. *::*:** : . . * : . . . .: ", "identical_positions": 225, "similar_positions": 242, "identity": "22.32%" }, { "cls_id": "homologset.agr.RGD:1308948", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZY73-1", "uniprot_id": "D3ZY73_RAT", "id": "D3ZY73-1", "name": "", "aln": "-------MLRDALDFNSSGSGSEGSVFTKSEHSIIAAYLIVA-------------------------------------------------------------------------------------------------GRRMTGNTYLSMVLGAWINGLFWALMPIVGWASYAPDPTGATCTINWRKNDTSFVSYTMMVIVVNFIVPLTVMFYCYYHVSQSMRLSAASNCTTHLNRDWAHQADVTKMSVMMILMFLLAWSPYSVVCLWACFGNPKKIPPSLAIIAPLFAKSSTFYNPCIYVAANKKFRKAMFAMLKCQPHQAMPEPSTLAMGVPHSPLAPARI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35214-1", "uniprot_id": "OPSX_MOUSE", "id": "O35214-1", "name": "Visual pigment-like receptor peropsin", "aln": "-------MLSEASDFNSSGSRSEGSVFSRTEHSVIAAYLIVAGITSILSNVVVLGIFIKYKELRTPTNAVIINLAFTDIGVSSIGYPMSAASDLHGSWKFGHAGCQIYAGLNIFFGMVSIGLLTVVAMDRYLTISCPDVGRRMTTNTYLSMILGAWINGLFWALMPIIGWASYAPDPTGATCTINWRNNDTSFVSYTMMVIVVNFIVPLTVMFYCYYHVSRSLRLYAASDCTAHLHRDWADQADVTKMSVIMILMFLLAWSPYSIVCLWACFGNPKKIPPSMAIIAPLFAKSSTFYNPCIYVAAHKKFRKAMLAMFKCQPHLAVPEPSTLPMDMPQSSLAPVRI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14718-1", "uniprot_id": "OPSX_HUMAN", "id": "O14718-1", "name": "Visual pigment-like receptor peropsin", "aln": "-------MLRNNLGNSSDSKNEDGSVFSQTEHNIVATYLIMAGMISIISNIIVLGIFIKYKELRTPTNAIIINLAVTDIGVSSIGYPMSAASDLYGSWKFGYAGCQVYAGLNIFFGMASIGLLTVVAVDRYLTICLPDVGRRMTTNTYIGLILGAWINGLFWALMPIIGWASYAPDPTGATCTINWRKNDRSFVSYTMTVIAINFIVPLTVMFYCYYHVTLSIKHHTTSDCTESLNRDWSDQIDVTKMSVIMICMFLVAWSPYSIVCLWASFGDPKKIPPPMAIIAPLFAKSSTFYNPCIYVVANKKFRRAMLAMFKCQTHQTMPVTSILPMDVSQNPLASGRI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N2G0-1", "uniprot_id": "A0A8M1N2G0_DANRE", "id": "A0A8M1N2G0-1", "name": "Visual pigment-like receptor peropsin", "aln": "MIMCDKEMESGLLNVSAETVYGEKSAFTQTEHNIVAAYLITAGVISLSSNIVVLLMFVKFRELRTATNAIIINLAFTDIGVAGIGYPMSAASDLHGSWKFGYMGCQIYAALNIFFGMASIGLLTVVAIDRYLTICRPDIGQKLTTRSYTLLIVAAWLNAVFWSSMPIVGWAGYAPDPTGATCTINWRNNDTSFVSYTMTVITVNFIIPLSVMFYCYYNVSATVKRFKASNCLDSINMDWSDQMDVTKMSVIMIVMFLAAWSPYSIVCLWASFGDPQKIPAPMAIIAPLLAKSSTFYNPCIYVIANKKFRRAIIGMIRCQTRQRVTINNQLPMMASSVPLNP---", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . .:. : *.*:::**.::*:*** * *:::* .:* :::.**:*.:**: ***:***.***************:** ******* **.:***:**:*******:*: ::: :*:* :: **:.* *******:** *** ******:*****.**:*:***..:******:************* *:****:*::.*::**.: :. . *.* . .* . ", "identical_positions": 128, "similar_positions": 69, "identity": "37.21%" }, { "cls_id": "homologset.agr.RGD:1308949", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5PQL5-1", "uniprot_id": "PTSS1_RAT", "id": "Q5PQL5-1", "name": "Phosphatidylserine synthase 1", "aln": "---------------------------------------MASCVGSRTLSKDDVN---------------YRMHFRMINEQQVEDITIDFFYRPHTITLLSFTIISLMYFAFTRDDCVPEDNIWRGILSVIFFFLIISVLAFPNGPFTRPHPALWRMVFGLSVLYFLFLVFLLFLNFEQVKSLMYWLDPNLRYATREADIMEYAVNCHVITWERIVSHFDIFAFGHFWGWAMKALLIRSYGLCWTISITWELTELFFMHLLPNFAECWWDQVILDILLCNGGGIWLGMVVCRFLEMRTYHWASFKDIHTTTGKIKRAVLQFTPASWTYVRWFDPKSSFQRVAGIYLFMIIWQLTELNTFFLKHIFVFQASHPLSWCRILFIGCITAPTVRQYYAYLTDTQCKRVGTQCWVFGVIGFLEAIVCIKFGQDLFSKTQILYVVLWLLCVAFTTFLCLYGMVWYAEHYGHREKTYSECEDGTYSPEISWYHGKGSKGSEDSPPKHSNNNESHSSRRRNRHSKSKVTNGVGKK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99LH2-1", "uniprot_id": "PTSS1_MOUSE", "id": "Q99LH2-1", "name": "Phosphatidylserine synthase 1", "aln": "---------------------------------------MASCVGSRTLSKDDVN---------------YRMHFRMINEQQVEDITIDFFYRPHTITLLSFTIISLMYFAFTRDDSVPEDNIWRGILSVIFFFLIISVLAFPNGPFTRPHPALWRMVFGLSVLYFLFLVFLLFLNFEQVKSLMYWLDPNLRYATREADIMEYAVNCHVITWERIVSHFDIFAFGHFWGWAMKALLIRSYGLCWTISITWELTELFFMHLLPNFAECWWDQVILDILLCNGGGIWLGMVVCRFLEMRTYHWASFKDIHTTTGKIKRAVLQFTPASWTYVRWFDPKSSFQRVAGIYLFMIIWQLTELNTFFLKHIFVFQASHPLSWGRILFIGCITAPTVRQYYAYLTDTQCKRVGTQCWVFGVIGFLEAIVCIKFGQDLFSKTQILYVMLWLLCVAFTTFLCLYGMVWYAEHYGHREKTYSECEDGTYSPEISWHHGKGSKGSEDSPPKHSSNHESHSSRRRNRHSKSKVTNGVGKK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P48651-1", "uniprot_id": "PTSS1_HUMAN", "id": "P48651-1", "name": "Phosphatidylserine synthase 1", "aln": "---------------------------------------MASCVGSRTLSKDDVN---------------YKMHFRMINEQQVEDITIDFFYRPHTITLLSFTIVSLMYFAFTRDDSVPEDNIWRGILSVIFFFLIISVLAFPNGPFTRPHPALWRMVFGLSVLYFLFLVFLLFLNFEQVKSLMYWLDPNLRYATREADVMEYAVNCHVITWERIISHFDIFAFGHFWGWAMKALLIRSYGLCWTISITWELTELFFMHLLPNFAECWWDQVILDILLCNGGGIWLGMVVCRFLEMRTYHWASFKDIHTTTGKIKRAVLQFTPASWTYVRWFDPKSSFQRVAGVYLFMIIWQLTELNTFFLKHIFVFQASHPLSWGRILFIGGITAPTVRQYYAYLTDTQCKRVGTQCWVFGVIGFLEAIVCIKFGQDLFSKTQILYVVLWLLCVAFTTFLCLYGMIWYAEHYGHREKTYSECEDGTYSPEISWHHRKGTKGSEDSPPKHAGNNESHSSRRRNRHSKSKVTNGVGKK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q803C9-1", "uniprot_id": "PTSS1_DANRE", "id": "Q803C9-1", "name": "Phosphatidylserine synthase 1", "aln": "---------------------------------------MATTFRSQTLSKDDVN---------------YRMHFRMINEQQVEDITIQFFYKPHTISLLTVTVLSLMYFAFTRDDGDPDSNLRVGLILLVSFFLVISVLAFPNGPFTRPHPAIWRIVFGLSVLYFLFLVFIIFLNWDQVKALMFWLDPNLRYAKREADVMEYAVNCHVITWERILSHFDIFAFSHFWGWGMKALLIRSYGLCWTISITWELTELFFMHLLPNFAECWWDQVILDILLCNGGGIWLGMTVCRFLEMRTYHWASIKDIHSTTGKIKRAVLQFTPASWTYVRWLDPKSSLQRVMGVYLFMIIWQLTELNTFFLKHIFVFPACHALSWCRILFIGIITAPTVRQYYAYLTDTQCKRVGTQCWVFGAIAFLEALACIKFGQDLFSKTQILYVILWLVCLAFITFLCLYVMVWYAENYGPRQKSFSECEDSIYS-------EAGDSVTECKGEFEIDSTTSCSTRKRRDSGDSRTINGMEK--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8N7T7D0-1", "uniprot_id": "A0A8N7T7D0_DANRE", "id": "A0A8N7T7D0-1", "name": "Phosphatidylserine synthase", "aln": "---------------------------------------MAPSQGSRMLSKDDAD---------------YKLHFRMINEQQVEDITIDFFYKPHTITLLTFTVVSIMYFAFTRDDGDSDKNLRVGLLLVVSFFLVISVLAFPNGPFTRPHPSVWRMVFGLSVLYFLFLVFLIFLNWDQVKALLYWLDPNLRYAKREADVMEYAVNCHVITWERILSHFDIFALGHFWGWAMKALLIRSYGLCWTISITWELTELFFMHLLPNFAECWWDQVILDILLCNGGGIWLGMTVCRFLEMRTYRWASIKDIHSTSGKLKRAVLQFTPASWTYVRWFDPKSSFQRVAGIYLFMIVWQLTELNTFFLKHIFVFQASHPLSWCRILFIGIITAPTVRQYYAYVTDTQCKRVGTQCWVFGAIAFLEALACIKFGHDLFSNTQALYVVFWLLCLAFITFLCLYGMVWYEQNYGKKLKRIPD-DDGTST-------DPYDSLPEAAKERSSSSNSSSS--RRRKGGKHKTANGTSGKK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VPD3-1", "uniprot_id": "PTSS_DROME", "id": "Q9VPD3-1", "name": "Phosphatidylserine synthase", "aln": "MKKRTNSRGTPTSSGDALLDTSFSSAGDAERDHPAYKSGAASAPATPTKRRDGSDGSVSSAGARRKRKDEIAQTFVIVNERPVDDISLDFFYKPHTITLLAVSVLAVMYFAFVRNEANVDENLWAGLLCIVFFFLIVSVIAFPNGPFTRPHPAVWRILFGCSVLYLLTLQFLMFQNYPTIRSIFYWIDPKLKNFHIDMEK-EYGVNCSDISWDRVKGHLDVFAWGHFLGWAFKAILIRHMGILWAISVMWEITEITFAHLLPNFIECWWDALILDVIICNGLGIWMGLKICQILEMREYKWASIKDISTTTGKIKRAMLQFTPESWSAIRWLDPKSTAMRFAAVIQLVIFWQVTELNTFFLKHIFEMPPDHFIVIGRLIFIGLFVAPSVRQYYVYVTDTRCKRVGTQCWVYGAIMVSEAILCIKNGKELFERTQAINIVLWLTVQVIISVAFVYLAVYWQQRQLKKVS----------------------STPAKTKETIPASSSSPSKGKLSPQKEKKLK-------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. : :*. : * ::**: *:**:::***:****:**:.:::::*****.*:: :.*: *:: :: ***::**:************::**::** ****:* * *::* *: ::::::*:**:*: : : **.*** *:*:*: .*:*:** .** **.:**:*** *: *:**: **:**: * ****** ***** :***:::*** ***:*: :*::**** *:***:*** :*:**:***:***** **: :**:****: *. .: ::*.**:************ : . * : *::*** :.**:*****.*:***:**********:*.* . **: *** *::**..** : :::** .: :. :* ::: :. : . . . . * * : . : ", "identical_positions": 200, "similar_positions": 136, "identity": "37.88%" }, { "cls_id": "homologset.agr.RGD:1308950", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q13367-1", "uniprot_id": "AP3B2_HUMAN", "id": "Q13367-1", "name": "AP-3 complex subunit beta-2", "aln": "------------------MSAAPAYSEDKGGSAGP---------------GEPEYGHDPAS----------GGIFSSDYKRHDDLKEMLDTNKDSLKLEAMKRIVAMIARGKNASDLFPAVVKNVACKNIEVKKLVYVYLVRYAEEQQDLALLSISTFQRGLKDPNQLIRASALRVLSSIRVPIIVPIMMLAIKEAASDMSPYVRKTAAHAIPKLYSLDSDQKDQLIEVIEKLLADKTTLVAGSVVMAFEEVCPERIDLIHKNYRKLCNLLIDVEEWGQVVIISMLTRYARTQFLSPTQNESLLEENAEKAFYGSEEDEAKGAGSEETAAAAAPSRKPYVMDPDHRLLLRNTKPLLQSRSAAVVMAVAQLYFHLAPKAEVGVIAKALVRLLRSHSEVQYVVLQNVATMSIKRRGMFEPYLKSFYIRSTDPTQIKILKLEVLTNLANETNIPTVLREFQTYIRSMDKDFVAATIQAIGRCATNIGRVRDTCLNGLVQLLSNRDELVVAESVVVIKKLLQMQPAQHGEIIKHLAKLTDNIQVPMARASILWLIGEYCEHVPRIAPDVLRKMAKSFTAEEDIVKLQVINLAAKLYLTNSKQTKLLTQYVLSLAKYDQNYDIRDRARFTRQLIVPSEQGGALSRHAKKLFLAPKPAPVLESSFKDRDHFQLGSLSHLLNAKATGYQELPDWPEEAPDPSVRNVEVPEWTKCSNREKRKEKEKPFYSDSEGESGPTESADSDPESESESDSKSSSESGSGESSSESDNEDQDEDEEKGRGSESEQSEEDGKRK---TKKKVPERKGEASSSDEGSDSSSSSSESEMTSESEEEQLEPASWSRKTPPSSKSAPATKEISLLDLEDFTPPSVQPVSPPAIVSTSLAADLEGLTLTDSTLVPSLLSPVSGVGRQELLHRVAGEGLAVDYTFSRQPFSGDPHMVSVHIHFSNSSDTPIKGLHVGTPKLPAGISIQEFPEIESLAPGESATAVMGINFCDSTQAANFQLCTQTRQFYVSIQPPVGELMAPVFMSENEFKKEQGKLMGMNEITEKLMLPDTCRSDHIVVQKVTATANLGRVPCGTSDEYRFAGRTLTGGSLVLLTLDARPAGAAQLTVNSEKMVIGTMLVKDVIQALTQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LE23-1", "uniprot_id": "A0ABK0LE23_RAT", "id": "A0ABK0LE23-1", "name": "AP-3 complex subunit beta", "aln": "MQRFLQLPGTVVRPGARGADQEEASSPVLGPEGGPPPWYQALKPEELRWLQAPEEDTTPETSIEGPCPEVGQSQTQSQPLRHDDLKEMLDTNKDSLKLEAMKRIVAMIARGKNASDLFPAVVKNVACKNIEVKKLVYVYLVRYAEEQQDLALLSISTFQRGLKDPNQLIRASALRVLSSIRVPIIVPIMMLAIKEAASDMSPYVRKTAAHAIPKLYSLDSDQKDQLIEVIEKLLADKTTLVAGSVVMAFEEVCPERIDLIHKNYRKLCNLLIDVEEWGQVVIISMLTRYARTQFLSPTQNESLLEENPEKAFYGSEEDEAKGPGSEEAATAALPARKPYVMDPDHRLLLRNTKPLLQSRSAAVVMAVAQLYFHLAPKAEVGVIAKALVRLLRSHSEVQYVVLQNVATMSIKRRGMFEPYLKSFYIRSTDPTQIKILKLEVLTNLANETNIPTVLREFQTYIRSMDKDFVAATIQAIGRCATNIGRVRDTCLNGLVQLLSNRDELVVAESVVVIKKLLQMQPAQHGEIIKHLAKLTDNIQVPMARASILWLIGEYCEHVPKIAPDVLRKMAKSFTAEEDIVKLQVINLAAKLYLTNSKQTKLLTQYVLSLAKYDQNYDIRDRARFTRQLIAPSEQGGALSRHAKKLFLAPKPAPILESSFKDRDHFQLGSLSHLLNAKATGYQELPDWPEEAPDPSVRNVEVPEWTKCSNREKRKEKEKPFYSDSEGESGPTESADSEPESESESGSKSSSESGSGESSSESDNE--DDDEEKGEGSESEQSEEEGEKKKKTKKKKASEGHREGSSSEEGSDSSSSS-ESEVTSESEEEQVEPASWRKKTPPSSKSTPAAKEISLLDLEDFTSPSVQPVSPPMVVSTSLAADLEGLTLTDSSLVPSLLSPVSSIGRQELLHRVAGEGLAVDYAFSRQPFSGDPHMVSLHIYFSNNSETPIKGLHVGTPKLPAGISIQEFPEIESLAPGESTTTVMGINFCDSTQAANFQLCTQTRQFYVSIQPPVGELMAPVFMSENEFKKEQGKLTGMNEITEKLTLPDTCRSDHMVVQKVTATANLGRVPCGASDEYRFAGRTLTSGSLVLLTLDARGTGAAQLTVNSEKMVIGTMLVKDVIQALTQ", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * * * ..** ** . * : . .*: ***********************************************************************************************************************************************************************************************************************************.**************.****:*:** *:********************************************************************************************************************************************************************************************************************************:*********************************************************************.***********************:**********************************************************************************:*******.******************* *:*****.*********:*::* .***..* : *.***:********* ***:********:***** :********:**:************.********* :*****************:**********.:******************:**************:**:***.*:*********************************:*:***************************************************** ********* *********:*****************:************.*********** :****************************", "identical_positions": 1001, "similar_positions": 50, "identity": "88.74%" }, { "cls_id": "homologset.agr.RGD:1308951", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZV46-1", "uniprot_id": "D3ZV46_RAT", "id": "D3ZV46-1", "name": "", "aln": "MPGHNPRRRLRRRHPLGREMESRAYPLNLTLKEEQKEDEVEIQELEDGPVEMQKVQICSEGTWVPALFDEVAIYFSDEEWEVLTEQQKALYREVMRMNYETVLSLEFPFPKPDMINRLEREEECPESDEWRLQGVTFAENEESDFRTPDWANPMNATSHFPQPQHFNSFGLRLPQDITELPEWSEGYPFYMAMGFPGYDLSADDLASKFQFSRGMRRSYDAGFKLMVVEHAESTNNCQAAKQFGVLEKNVRDWRKVKPQLQNAHAMRRAFRGPKNGRFALVDQRVAEYVRYMQAKGDPITREAMQLKALEIAQEMNIPEKGFKASLGWCRRMMRRYDLSLRHKVPVPQHLAEDLTEKLVTYQQSVLALRRTHDYEVAQMGNADETPICLEVPSRVTVDNQGEKPILVKTPGREKLRITAMLGVLADGRKLPPYIILRGTYIPPGKFPSGMEIRCHRYGWMTEDLMQDWLEVVWRRRTGAVPKQRGMLILNGFRCHATDSVKTSMESMNTDMVIIPGGLTSQLQVLDVVVYKPLNDSVRAQYSNWLLAGNLALSPTGNAKKPPLGLFLEWIMVAWNSISSESIVQGFRKCHISSNLEEEGDVLWEIEGELP--KER----GHEGVAEDD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80TC5-1", "uniprot_id": "POGK_MOUSE", "id": "Q80TC5-1", "name": "Pogo transposable element with KRAB domain", "aln": "-------------------MESRAYPLNLTLKEEQKEEEVEIQELEDGPIDMQKVQICSEGAWVPALFDEVAIYFSDEEWEVLTEQQKALYREVMRMNYETVLSLEFPFPKPDMINRLERDEECPNSDEWRLQGVTFAENEESDFRTPDWASPTNATSHFPQPQPFNSFGLRLPQDITELPEWTEGYPFYMAMGFPGYDLSADDLASKFQFSRGMRRSYDAGFKLMVVEYAESTNNCQAAKQFGVLEKNVRDWRKVKPQLQNAHAMRRAFRGPKNGRFALVDQRVAEYVRYMQAKGDPITREAMQLKALEIAQEMNIPEKGFKASLGWCRRMMRRYDLSLRHKVPVPQHLAEDLTEKLVTYQQSVLALRRTHDYEVAQMGNADETPICLEVPSRVTVDNQGEKPILVKTPGREKLRITAMLGVLADGRKLPPYIILRGTYIPPGKFPSGMEIRCHRYGWMTEDLMQDWLEVVWRRRTGAVPRQRGMLILNGFRCHATDSVKSSMENMNTDMVIIPGGLTSQLQVLDVVVYKPLNDSVRAQYSNWLLAGNLALSPTGNAKKPPLGLFLEWIMVAWNSISSESIVQGFRKCHISSNLEDEGDVLWEIEGELP--KEPPKECGPESVAEGD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P215-1", "uniprot_id": "POGK_HUMAN", "id": "Q9P215-1", "name": "Pogo transposable element with KRAB domain", "aln": "-------------------MESTAYPLNLSLKEEEEEEEIQSRELEDGPADMQKVRICSEGGWVPALFDEVAIYFSDEEWEVLTEQQKALYREVMRMNYETVLSLEFPFPKPDMITRLEGEEESQNSDEWQLQGGTSAENEESDVKPPDWPNPMNATSQFPQPQHFDSFGLRLPRDITELPEWSEGYPFYMAMGFPGYDLSADDIAGKFQFSRGMRRSYDAGFKLMVVEYAESTNNCQAAKQFGVLEKNVRDWRKVKPQLQNAHAMRRAFRGPKNGRFALVDQRVAEYVRYMQAKGDPITREAMQLKALEIAQEMNIPEKGFKASLGWCRRMMRRYDLSLRHKVPVPQHLPEDLTEKLVTYQRSVLALRRAHDYEVAQMGNADETPICLEVPSRVTVDNQGEKPVLVKTPGREKLKITAMLGVLADGRKLPPYIILRGTYIPPGKFPSGMEIRCHRYGWMTEDLMQDWLEVVWRRRTGAVPKQRGMLILNGFRGHATDSVKNSMESMNTDMVIIPGGLTSQLQVLDVVVYKPLNDSVRAQYSNWLLAGNLALSPTGNAKKPPLGLFLEWVMVAWNSISSESIVQGFKKCHISSNLEEEDDVLWEIESELPGGGEPPKDCDTESMAESN", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *** ******:****::*:*:: :****** :****:***** *****************************************************.*** :**. :****:*** * *******.:.***..* ****:***** *:*******:********:********************:*.**********************:************************************************************************************************************************.***********:*******:*********************************:**********:*****************************************************************:*********** *******.***.***************************************************************:****************:*********:*.*******.*** * . *.:**.:", "identical_positions": 545, "similar_positions": 44, "identity": "86.78%" }, { "cls_id": "homologset.agr.RGD:1308952", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z2M4-1", "uniprot_id": "DECR2_RAT", "id": "Q9Z2M4-1", "name": "Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTQQPPDVEED---------------------DCLSEYHHLFCPDLLQDKVAFITGGGSGIG----FRIAEIFMRHG-----CHTVIVSR------------------SLPRVSEAAKKLVAATGKRCLPLSMDVR---------------------VPPAVMAAVD----------------------------QALKEFG-------KIDILIN----CAAGNFLCPASALSFNAFKTVVDIDTLGTFNVSRVLY--EKFFRDHGGVIVNITATLSMRGQVLQLHAGAAKAAVDAMTR----------HLAVEWGPQNIRVNSLAPGAISGTEGLRRLGGPKASSKFKYLSSPIPRLG-TKTEIAHSVLYLASPLASYVSGIVLVVDGGSWMTLPN--------DIGRLLEFESSSAKL-----------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75154-1", "uniprot_id": "RFIP3_HUMAN", "id": "O75154-1", "name": "Rab11 family-interacting protein 3", "aln": "MASAPPASPPGSEPPGPDPEPGGPDGPGAAQLAPGPAELRLGAPVGGPDPQSPGLDEPAPGAAADGGARWSAGPAPGLEGGPRDPGPSAPPPRSGPRGQLASPDAPGPGPRSEAPLPELDPLFSWTEEPEECGPASCPESAPFRLQGSSSSHRARGEVDVFSPFPAPTAGELALEQGPGSPPQPSDLSQTHPLPSEPVGSQEDGPRLRAVFDALDGDGDGFVRIEDFIQFATVYGAEQVKDLTKYLDPSGLGVISFEDFYQGITAIRNGDPDGQCYGGVASAQDEEPLACPDEFDDFVTYEANEVTDSAYMGSESTYSECETFTDEDTSTLVHPELQPEGDADSAGGSAVPSECLDAMEEPDHGALLLLPGRPHPHGQSVITVIGGEEHFEDYGEGSEAELSPETLCNGQLGCSDPAFLTPSPTKRLSSKKVARYLHQSGALTMEALEDPSPELMEGPEEDIADKVVFLERRVLELEKDTAATGEQHSRLRQENLQLVHRANALEEQLKEQELRACEMVLEETRRQKELLCKMEREKSIEIENLQTRLQQLDEENSELRSCTPCLKANIERLEEEKQKLLDEIESLTLRLSEEQENKRRMGDRLSHERHQFQRDKEATQELIEDLRKQLEHLQLLKLEAEQRRGRSSSMGLQEYHSRARESELEQEVRRLKQDNRNLKEQNEELNGQIITLSIQGAKSLFSTAFSESLAAEISSVSRDELMEAIQKQEEINFRLQDYIDRIIVAIMETNPSILEVK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :..:* . :** : : :: :: .: ::* . :: .* *: * . :*:* *: :.* . .*:::* :* ..* .:: : **. : *:: : ::::* . : * * *: ** *:.: :.: *.. :. *::.:. : :::.. *.: .. *. * *: .:.*: . : : * : *::*. .:. : * : * ::: *.: : :*. ::*: .. * : : . ::* . :** :* *..* . : ", "identical_positions": 47, "similar_positions": 119, "identity": "6.22%" }, { "cls_id": "homologset.agr.RGD:1308953", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6G3L4-1", "uniprot_id": "A0A8I6G3L4_RAT", "id": "A0A8I6G3L4-1", "name": "", "aln": "--------MMLPR-TWAVE-----TEQLLTPNPG-------------------------YGTQAGTSPAPTTPP----------------EEEDLRRRLKYFFMSPCDKFRAKGRKPCKLMLQVVKILVVTVQLILFGLSNQLVVTFREENTIAFRHLFLLGYSDG--------SDDTFAAYTREQLYQAIFYAVDQYLTLPEISLGRYAYVRGGGGPWANGSALALCQRYYHRGHVDPANDTFDIDPRVVTDCIQVDPPDRPPDIPSEDLDFLDGSTSYKNITLKFHKLINVTIHFQLKTINLQSLIN-NEIPDCYTFSILITFDNKAHSGRIPIRLETQTHIQECKHPS---VSRHGDNSFRLLFDVVVILTCSLSFLLCARSLLRGFLLQNEFVVFMWRRRGREISLWERLEFVNGWYILLVTSDVLTISGTIMKIGIEAKNLAS--YDVCSILLGTSTLLVWVGVIRYLTFFHKYNILIATLRVALPSVMRFCCCVAVIYLGYCFCGWIVLGPYHVKFRSLSMVSECLFSLINGDDMFVTFAAMQAQQGRSSLVWLFSQLYLYSFISLFIYMVLSLFIALITGAYDTIKHPGGTGTEKSELQAYI-EQCQDSPTSGKFRRGSG--------STCSLLCCCGRNSPEDHSLLVN-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99J21-1", "uniprot_id": "MCLN1_MOUSE", "id": "Q99J21-1", "name": "Mucolipin-1", "aln": "--------MATPAGRRASE-----TERLLTPNPG-------------------------YGTQVGTSPAPTTPT----------------EEEDLRRRLKYFFMSPCDKFRAKGRKPCKLMLQVVKILVVTVQLILFGLSNQLVVTFREENTIAFRHLFLLGYSDG--------SDDTFAAYTQEQLYQAIFYAVDQYLILPEISLGRYAYVRGGGGPWANGSALALCQRYYHRGHVDPANDTFDIDPRVVTDCIQVDPPDRPPDIPSEDLDFLDGSASYKNLTLKFHKLINVTIHFQLKTINLQSLIN-NEIPDCYTFSILITFDNKAHSGRIPIRLETKTHIQECKHPS---VSRHGDNSFRLLFDVVVILTCSLSFLLCARSLLRGFLLQNEFVVFMWRRRGREISLWERLEFVNGWYILLVTSDVLTISGTVMKIGIEAKNLAS--YDVCSILLGTSTLLVWVGVIRYLTFFHKYNILIATLRVALPSVMRFCCCVAVIYLGYCFCGWIVLGPYHVKFRSLSMVSECLFSLINGDDMFVTFAAMQAQQGHSSLVWLFSQLYLYSFISLFIYMVLSLFIALITGAYDTIKHPGGTGTEKSELQAYI-EQCQDSPTSGKFRRGSG--------SACSLFCCCGRDSPEDHSLLVN-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9GZU1-1", "uniprot_id": "MCLN1_HUMAN", "id": "Q9GZU1-1", "name": "Mucolipin-1", "aln": "--------MTAPAGPRGSE-----TERLLTPNPG-------------------------YGTQAGPSPAPPTPP----------------EEEDLRRRLKYFFMSPCDKFRAKGRKPCKLMLQVVKILVVTVQLILFGLSNQLAVTFREENTIAFRHLFLLGYSDG--------ADDTFAAYTREQLYQAIFHAVDQYLALPDVSLGRYAYVRGGGDPWTNGSGLALCQRYYHRGHVDPANDTFDIDPMVVTDCIQVDPPERPPPPPSDDLTLLESSSSYKNLTLKFHKLVNVTIHFRLKTINLQSLIN-NEIPDCYTFSVLITFDNKAHSGRIPISLETQAHIQECKHPS---VFQHGDNSFRLLFDVVVILTCSLSFLLCARSLLRGFLLQNEFVGFMWRQRGRVISLWERLEFVNGWYILLVTSDVLTISGTIMKIGIEAKNLAS--YDVCSILLGTSTLLVWVGVIRYLTFFHNYNILIATLRVALPSVMRFCCCVAVIYLGYCFCGWIVLGPYHVKFRSLSMVSECLFSLINGDDMFVTFAAMQAQQGRSSLVWLFSQLYLYSFISLFIYMVLSLFIALITGAYDTIKHPGGAGAEESELQAYI-AQCQDSPTSGKFRRGSG--------SACSLLCCCGRDPSEEHSLLVN-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VW35-1", "uniprot_id": "Q9VW35_DROME", "id": "Q9VW35-1", "name": "", "aln": "MQSYGPGAQTAPAVKRRTDSYEAAQQQQQSPESDEEYVNTRILRRQVQLQSTPVAPVVPMPISAGSGTAPPSVDGREEQPEFPGSSAASYQEERMRRKLQFFFMNPIEKWQAKRKFPYKFVVQIVKIFLVTMQLCLFAHSRYNHINYTGDNRFAFSHLFLRGWDSSREVESYPPAVGPFALYLKSEFFDTVQYAVNGYANVSR-SIGPYDYP----TPNNTMPPLKLCLQNYREGTIFGFNESYIFDPHIDEVCERLPPNVTTIG--------VENYLRQRDVEVNFASLVSAQLTFKIKTVNFKANGGPLSAPDCFRFDISITFNNRDHDGQMLLSLDAEATRLKCHGATDFISDANFDSMLRSVLNIFVLLTCALSFALCTRALWRAYLLRCTTVNFFRSQFGKELSFDGRLEFVNFWYIMIIFNDVLLIIGSALKEQIEGRYLVVDQWDTCSLFLGIGNLLVWFGVLRYLGFFKTYNVVILTLKKAAPKILRFLIAALLIYAGFVFCGWLILGPYHMKFRSLATTSECLFALINGDDMFATFATLSS---KATWLWWFCQIYLYSFISLYIYVVLSLFIAVIMDAYDTIKAYYKDGFPTTDLKAFVGTRTAEDISSGVFMTDLDDFDQTSFLDVVKSICCCGRCGRHQEPAQPNSGYTSLSSIMK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : :: :*:.. ..*...**.: :** :**:*::***.* :*::** : * *:::*:***::**:** **. *. :.: :* :** **** *:... : ..** * :.:::::: :**: * :. *:* * * * . . * ** : *:.* : *::: :** : * :: * . ::. ::: ::* .*:.. : *::**:*::: . . ***: *.: ***:*: *.*:: : *:::: :*: .: : *. :* ::::.*:***:*** **:*:* *.:**: * *: : *: :*: ****** ***::: .*** * *: :* **.: *. :*.**::** ..****.**:*** **:.**::* **: * *.::** .. :** *: ****::*****:*****: .*****:********.***::.: ::: :* *.*:********:**:*******:* .****** * ::*:*:: : :. :** * . . .. . :***** .:.. * ", "identical_positions": 212, "similar_positions": 199, "identity": "31.74%" }, { "cls_id": "homologset.agr.RGD:1308954", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LX00-1", "uniprot_id": "A0ABK0LX00_RAT", "id": "A0ABK0LX00-1", "name": "", "aln": "MGTEYNCCKVSLASSACLLLRFLWSLTFAYCTVLYLGTNKPSPGEHIELSEGKLSVSTAGAKHTSFLHEVPNHRRKTKAKAPLPPAEMKGMDVSSAEDPVESIPVSTEQHDNMIDKDIELSVVLPGDVLKSTTVHGSKPMMDLLVFLCAQYHLNPSSHTINLLSAEENLIKFKPNTPIGMLEVEKVILKPKSLDKK--KPTPIIPEKTVRVVINFKKTQKTIVRVSPHSPLQDLAPIICSKCEFDPLHTVLLKDYQAQEPLDLTKSLNDLGLRELYAMDISRAPSVTAFSKSSF-----QESCQISHNPDIVKEKENKGIFSFFQRSKKKREQ---TASAPATPLVSKHRPSFTR--SNTISKPYISNTLPSDAPKKRRAPLPPMPTSQGAAQG----QERRASCVERSTSVDDTDKSSSEGFMVRTGSLQLSGSTSVGTSSLKRTKRKAPAPPSKPSLTETDEGSSAAAHGLPLEDGIVPDSISEVSSPEGMSSP--------------------------------------AGVSSDYSLEEIDEKEELMEASKDQAG--SVKSPTIASASTDMIITAENDPDSALSISDGETSPGSKGNTPEGRNPEGQGPHHPVECLIGNENNVSDSIKDLKTLSPNQESVIQNEVVVCAT-STDYVKNRPREMEATIEG--EAQKKVGDVEAERLSGSPAGRMDDVQSSRENHLTASPGPDQKSNQPRVEKTKMQDAAIQATPACSTFDGNHEAHNSPDLRVDETAQTLGSSTSTQHSSASFQDSVNASREVRSQGTS-TYVQDRLPVKEAACTYGNNDALSPIDGSGKNPAASSLKNFPLYRQDNHPKPKPSNEITREYIPKIGMTTYKIVPPKSLEVVKDWDSEAAGKKDNQKTLAVAQKHAIETMTETAVQAEALVTSKNSQQPQPDRTPKPSSGTEHPLHRTVSSPVGTEMNPPK-PPRMTTDTGTIPFAPNLEDINNILESKFRSRASNPQAKPSSFFLQMQKRASGHYVTSAAAKSVHTAPGPTPKEPTIKEVQRDPQLPPEQCLSPLSERTHSAPLPNISKADDNRIQKPAETSPPPVAPKPMALPAETSPPAVAPKPMAFPAETSLPPVSPKPMALPTEASSSPISPKPMAPPAEASIPPVVPKPMAPPAEASPLPVAPKPMAFPAETSLPPVAPKPMALPTEASPPPVAPKPLALPGSQGASLNLKTLKTFGAPRPYNSSAPSPFALAVVKRSQSFSKASPESPSEDSSAQPPAAIQDGKTQTVNQPTVGSQHDGVDKQNKPVQNEHSSQRLTPADGPSSFTLQRQSSLNFQSSDPEHIRQSLLTAIRSGEAAAKLKRVTVPSNRISVNGKSGLSQPMSIDAQDSC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UMF0-1", "uniprot_id": "COBL1_MOUSE", "id": "Q3UMF0-1", "name": "Cordon-bleu protein-like 1", "aln": "-----------MDRSVPDPLPRSAPRTPAMQPAGSAGKRR-----FMKMFHAHSKNDFVRIKNHKFLPLHICQSRKTKGKAPLPPAETKGTDVSSAEDPVESTAVVTEQQDNMIDKDIELSVVLPGDILKSTTVHGSKPMMDLLVFLCAQYHLNPSSHTIDLLSAEENLIKFKPNTPIGMLDVEKVILKPKSLDKK--KPTPIIPEKTVRVVINFKKTQKTIVRVSPHAPLQDLAPIICSKCEFDPLHTVLLKDYQAQEPLDLTKSLNDLGLRELYAMDISR------------------ESCQISHNPDIVKEKENKGIFSFFQRSKKKREQ---TASAPATPLVSKHRPSFTR--SNTISKPYISNTLPSDAPKKRRAPLPPMPTSQGAAQG----QERRASCVERSTSVDDTDKSSSEAIMVRTGSLQLS-STSIGTSSLKRTKRKAPAPPSKTPLAQTDERNSAMAHGLPLEDGIAPDSMLELSSPEGMSTPEGSLGPGFLSQEQCAVPKPPDEISEGPGTPETAVASLTSGVSSDYSLEEIDEKEELSEASKDPAGSISVKSPDIASASTDMRITVEKDPDSALGISDGETSPSSKGKTQEGRSTEGQGPYHPVVGHIGNEDRVSDSIKDMKTLGPNQESVVQNEIMVCAT-STDYVKNRPGKMETTIEGEGEALKKASDMETDRLSGSPACRMDNVKSSRENHLTASPGPDQKLNQPGVEKTKMQDAAIQATPARGTFDGNHEVSNSSDPRADETVQTSDGSISAQHSSASLQDSVNASREFRSQGTS-TYVQDRLPEKEPACTYGNNVPLSPVDGSNKNPAASYLKNFPLYRQDSNPKPKPSNEITREYIPKIGMTTYKIVPPKSLEMAKDWESEAMGRKDDQKMLPVGQRHTIENMTETSMQTEVPATSKSSQQPQPDLKPKPSSGTERHLHRTLSSPTGTETNPPK-APRVTTDTGTIPFAPNLEDINNILESKFRSRASNPQAKPSSFFLQMQKRASGHYVTSAAAKSVHTAPGPAPKEPTIKEVQRDPQLSPEQHPSSLSERTHSAPLPNISKADDDIIQKPAETSPPPVAPKPMTLRAETSPPPVFPKPMTLPAETSPPPVFPKPMTLP------------------------------------------------AETSLPLVFPKPMTLRAETSPPPVAAKPVALPGSQGTSLNLKTLKTFGAPRPYSSSGPSPFALAVVKRSQSFSKACPESASEGSSALPPAATQDEKTHTVNKPTVGSQHGDGDKQNNPVQNEHSSQVLTPADGPS-FTLKRQSSLTFQSSDPEHVRQSLLTAIRSGEAAAKLKRVTVPSNTISVNGKSGLSQSMSIDAQDSR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q53SF7-4", "uniprot_id": "COBL1_HUMAN", "id": "Q53SF7-4", "name": "Cordon-bleu protein-like 1", "aln": "------------------------------------------------------------MDGRTPRPQDAPARRKPKAKAPLPPAETKYTDVSSAADSVESTAFIMEQKENMIDKDVELSVVLPGDIIKSTTVHGSKPMMDLLIFLCAQYHLNPSSYTIDLLSAEQNHIKFKPNTPIGMLEVEKVILKPKMLDKK--KPTPIIPEKTVRVVINFKKTQKTIVRVSPHASLQELAPIICSKCEFDPLHTLLLKDYQSQEPLDLTKSLNDLGLRELYAMDVNR------------------ESCQISQNLDIMKEKENKGFFSFFQRSKKKRDQ---TASAPATPLVNKHRPTFTR--SNTISKPYISNTLPSDAPKKRRAPLPPMPASQSVPQDLAHIQERPASCIVKSMSVDETDKSPCEAGRVRAGSLQLS-SMSAGNSSLRRTKRKAPSPPSKIPPHQSDENS--RVTALQPVDGVPPDSASEANSPEELSSP--------------------------------------AGISSDYSLEEIDEKEELSEVPKVEAENISPKSQDIPFVSTDIINTLKNDPDSALGNGSGEFSQNSMEEKQETKSTDGQEP-HSVVYDTSNGKKVVDSIRNLKSLGPNQENVVQNEIIVYPENTEDNMKNGVKKTEINVEG--VAKNNNIDMEVERPSNSEAHETDTAISYKENHLAASSVPDQKLNQPSAEKT--KDAAIQTTPSCNSFDGKHQDHNLSDSKVEECVQTSNNNISTQHSCLSSQDSVNTSREFRSQGTLIIHSEDPLTVKDPICAHGNDDLLPPVDRIDKNSTASYLKNYPLYRQDYNPKPKPSNEITREYIPKIGMTTYKIVPPKSLEISKDWQSETIEYKDDQDMHALGKKHTHENVKETAIQTEDSAISESPEEPLPNLKPKPNLRTEHQVPSSVSSPDDAMVSPLKPAPKMTRDTGTAPFAPNLEEINNILESKFKSRASNAQAKPSSFFLQMQKRVSGHYVTSAAAKSVHAAPNPAPKELTNKEAERDMLPSPEQTLSPLSKMPHSVPQPLVEKTDDDVIG---------------------------------------------------------------------------------------------------------------QAPAEASPPPIAPKPVTIPASQVSTQNLKTLKTFGAPRPYSSSGPSPFALAVVKRSQSFSKERTESPSASALVQPPANTEEGKTHSVNKFVDIPQLGVSDKENNSAHNEQNSQIPTPTDGPS-FTVMRQSSLTFQSSDPEQMRQSLLTAIRSGEAAAKLKRVTIPSNTISVNGRSRLSHSMSPDAQDGH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6Z2T6-1", "uniprot_id": "A0A8M6Z2T6_DANRE", "id": "A0A8M6Z2T6-1", "name": "", "aln": "-----------MTADSRAKLQRRSSARDCRAAAG---------------------------MDGNAHNRPPDRRRSTKSKAPPPPVLTGLDAPLLSHKLQAFPHPAMEQTESLLEQELTLTVILPGGAEKITTVHGSKPMMDLLVMLCAQHHLNPSGHTLELITTNRNHVKFKPNALIGALEADKILLKPKGMEDKSKKTGPHMPEATVRLVINYRKTQKTILRVSPRVPLRELLPAICQKCEFDPQTTLLSPSVQSEDTLDLSGSLNDFGLREVYARDTRVISPVSPISPVSLPPSPTRSEIFYHGKEKSLREKDNKRRFSLFRRGSKKQSEQSMTVSAPASPVHRKQRPVSMSSFSTHVPLSYDCNTMPSDTPKKRRAPLPPSMMSQSMPSD-----------LSQTQTTVHPDGNQNLSSLSRASSTESSFKKSS-------TKRKAPPPP-----------------VMISTDTTHQDTTDSSMTESAVTSP----------------------------------------------LEEIKEQEEMSVGAGVNVEDETLED----NSSLNMSANISLDSGRAGTATPSQDSVTLESGTPRDDPVCDLSTDAEVAEGTVNGEMKADQTRSSHITSEDKDPGKTEQLIQPSE-------SGPVLEEVTVSN--------TSLPQRSECGIQTSQTDLQVQCFDSDTAISS-PESSCSIYAEAQTSKTIPNTSSLTHTETQTQVQSSNEPSSLCTEFSTSTIGLKKDMATSTDELQPSIQQSKDLTSTSKPASVSYVTDAEPKPKPSNEHTRGYIPKVGMTTYTIVPQKSLEKLHSLEIEMTLEP--KVDCKPNVSNGTVTLNGHQNAFAQTNQCTSPPATNSTNLSTNLSTKPTSLSANTTYSSTKPTSSSTSPTYLSTNPTNWSTNPINSSTSPTYLSTNPSNSSTNPTNSSTKQTNSSTNPTNSSSVDERIDSVSLKDKKVPPATRPKPASFRVPQHKRMSGDYVSSAAVRRASIGSSSSSSSCCSSPAARPKESLSSPQSDVFPAMEIFPPPPPPVQWEEEQSQSTSAKSLPQNEE----------------------------------------------------------------------------------------------IDAALPEAPKIPPSSFLSRQKSLPTNPAPSLSLEKLRSFAAPKPYSPSSPSRFAQAVSSAVK-----------RSQSLSHHAPVQETRTHTLTKQRPIRESPEPPTSTVADNGDREPETQTADTDPVMGTCKIGN--TQASPGSEASSQEVSDVFHSAEE----------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *..*.*** **. : . ** :.:::::: *:*:***. * *************::****:*****.:*::*::::.* :*****: ** *:.:*::**** ::.* *. * :** ***:***::******:****: .*::* * **.****** *:* . *:::.***: ****:****:** * .. : . ::**:** **:*:*..**:.: *.****:*: *:** *. :. .* .**:***:********** **. ... : :: :. ..* . . *:.* : * . * ******.** : * *: . : . :::* ****.*:**: . . : :. * :: . . *.. * .: * . . . . * * . *. :. : . ::: :::: . . * .:.. .: .. : . * . :.. : *. *:.. . :* . .: . : :. : .. .: ..* . . . * . * *:: *::. * .. . .. : : * . . .. . *: : . . :* :: : . * .* : : : .. : .: . . . . :: :. * . .. * .. :. :.* .: .* : ..: * .: . . :..::: : :. * :. .. .:.**:** : :** **.**:***.: . ....:... . . * .. . :. * * : ::: .: .*... .: ::* . .: .*:.*::*.**:**..*.** ** ** . : . * :: :*:::.: : ... . :.::..: *. .* * . . *...* *.: .::*.* ", "identical_positions": 234, "similar_positions": 350, "identity": "17.07%" }, { "cls_id": "homologset.agr.RGD:1308955", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0JPQ9-1", "uniprot_id": "CHID1_RAT", "id": "A0JPQ9-1", "name": "Chitinase domain-containing protein 1", "aln": "MWP----LLHVLWLALVCGSVHTTLS-KSDAKKAASKTLLEKTQFSDKPVQDRGLVVTDIKAEDVVLEHRSYCSARARERNFAGEVLGYVTPWNSHGYDVAKVFGSKFTQISPVWLQLKRRGREMFEITGLHDVDQGWMRAVKKHAKGVR------IVPRLLFEDWTYDDFRSVLDSEDEIEELSKTVVQVAKNQHFDGFVVEVWSQLLSQKHVGLIH-MLTHLAEALHQARLLVILVIPPAVTPGTDQLGMFTHKEFEQLAPILDGFSLMTYDYSTSQQPGPNAPLSWIRACVQVLDPK-----SQWRSKILLGLNFYGMDYAASKDAREPVIGARYIQTLKDHRPRVVWDSQAAEHFFEYKKNRGGRHVVFYPTLKSLQVRLELARELGVGVSIWELGQGLDYFYDLL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q922Q9-1", "uniprot_id": "CHID1_MOUSE", "id": "Q922Q9-1", "name": "Chitinase domain-containing protein 1", "aln": "MWP----LLHVLWLALVCGSVHTTLS-KSDAKKAASKMLLEKTQFSDKPVQDRGLVVTDIKAEDVVLEHRSYCSSRARERNFAGEVLGYVTPWNSHGYDVAKVFGSKFTQISPVWLQLKRRGREMFEITGLHDVDQGWMRAVKKHAKGVR------IVPRLLFEDWTYDDFRNVLDSEDEIEELSKTVAQVAKNQHFDGFVVEVWSQLLSQKHVGLIH-MLTHLAEALHQARLLVILVIPPAVTPGTDQLGMFTHKEFEQLAPILDGFSLMTYDYSTSQQPGPNAPLSWIRACVQVLDPK-----SQWRSKILLGLNFYGMDYAASKDAREPVIGARYVQTLKDHRPRVVWDSQAAEHFFEYKKNRGGRHVVFYPTLKSLQVRLELARELGVGVSIWELGQGLDYFYDLL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BWS9-1", "uniprot_id": "CHID1_HUMAN", "id": "Q9BWS9-1", "name": "Chitinase domain-containing protein 1", "aln": "MRT----LFNLLWLALACSPVHTTLS-KSDAKKAASKTLLEKSQFSDKPVQDRGLVVTDLKAESVVLEHRSYCSAKARDRHFAGDVLGYVTPWNSHGYDVTKVFGSKFTQISPVWLQLKRRGREMFEVTGLHDVDQGWMRAVRKHAKGLH------IVPRLLFEDWTYDDFRNVLDSEDEIEELSKTVVQVAKNQHFDGFVVEVWNQLLSQKRVGLIH-MLTHLAEALHQARLLALLVIPPAITPGTDQLGMFTHKEFEQLAPVLDGFSLMTYDYSTAHQPGPNAPLSWVRACVQVLDPK-----SKWRSKILLGLNFYGMDYATSKDAREPVVGARYIQTLKDHRPRMVWDSQASEHFFEYKKSRSGRHVVFYPTLKSLQVRLELARELGVGVSIWELGQGLDYFYDLL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7SYK0-1", "uniprot_id": "CHID1_DANRE", "id": "Q7SYK0-1", "name": "Chitinase domain-containing protein 1", "aln": "MRA----DWTFLLVCLLLPVVRSTLS-KTDAKKAS-KVQEAESSVAERPAQDRGLVVTDPQWRDIVREEKRFCHQCINTRQFKGAVLGYITPWNSHGYDIAKLFGPKLTSVSPVWLQLRRRGPESFHITGLHDHDPGWVKAVRKANKKNK------ILPRLLFDGWSYQDYVSVLDSEDEMEELGREALEVAKAEGFDGYTLELWSQLGGNKRKELVH-LVTHLCETLNAGKLTCVLVIPPSVAPGTGQPGMFGRDDFEKLAPVVDAFSLMTYDYSGPGRPGPSAPLPWVRECVLQLAPE-----NQWRHKILLGVNMYGLDFS-SHGGAEPLLGARCIELLKEVKPKLQWDENTGEHFFNYKRNNGVKHVVYYPTLKFLQLRISLAAELGTGISMWELGQGLDYFYDLL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VLS0-1", "uniprot_id": "Q9VLS0_DROME", "id": "Q9VLS0-1", "name": "Chitinase domain-containing protein 1", "aln": "MRAPDALLLRVALLLLLLTTVRGTLAPDSHKSKSKTKESALRGGPQDQDVFDLGLVSPEPLAKDIVSNHRGYFKETG-LRRFNGTTLGYVTPWNSHGYDVAKIFAKKFDIISPVWLQIVKQG-DRYAVAGTHDIDAGWLTDVRRKGKQVHNQRTVKVFPRFIFDHFTDRDIKLLLSDAQERTKVNDVLIKCCKDNGFDGLVLEVWSQLAGRIDDKILYTLVLQMAKELQKQQLRLILVIPP-FRKETGH--LFGEKHMDKLFKHIYAFSLMTYDFSSVQRPGANAPLYFVRKAVETIAPEGCADMTAKRAKILLGLNMYGNDYTPDGGG--PITFSQYLDLVRHVKKHLTYDERDVENFFEIK-NDDGRHIVFYPTLYSINERIKLAQELGTGISIWELGQGLNYFYDLF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . . : * *: **: .:. .*: * . :: . * *** .: ..:* :.: : *.* * .***:*********::*:*. *: :******: ::* : : ::* ** * **: *:: * : :.**::*: :: * :*.. :* ::. : .* : *** .:*:*.** .. ::: :: ::.: *: :* :***** . *.: :* ...:::* : .*******:* :**..*** ::* .* : *: . * *****:*:** *:: . .. *: :: :: ::. : :: :*.. *:**: * . . :*:*:**** :: *:.** ***.*:*:*******:*****:", "identical_positions": 127, "similar_positions": 137, "identity": "30.98%" }, { "cls_id": "homologset.agr.RGD:1308956", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q07243-1", "uniprot_id": "MTF1_MOUSE", "id": "Q07243-1", "name": "Metal regulatory transcription factor 1", "aln": "--------------------------------------------------------------------------------MGEHSPDDNIIFFKGEEDDLTPHDKMLRF------------------------------------------------------------------------------------------------------VDDNGLVPSSSGTVYDRTTVLIEQDPG--TLEDDEDDGQCGEPLPFLVEGEEGF-LIDQEAMSQGYVQHIISPDQIHLTINPGSTPMPRN-----IEGATLTLQSECPETKRKEVKRYQCTFEGCPRTYSTAGNLRTHQKTHRGEYTFVCNQEGCGKAFLTSYSLRIHVRVHTKEKPFECDVQGCEKAFNTLYRLKAHQRLHTGKTFNCESQGCSKYFTTLSDLRKHIRTHTGEKPFRCDHDGCGKAFAASHHLKTHVRTHTGERPFFCPSNGCEKTFSTQYSLKSHMKGHD----NKGTAYSALP---------------QHNGSEDTNHSLYLSELGLLSTDSELQENSSSTQDQDLSTISPAIIFESMFQNS-DDPGIQDDPLQTAALIDSFNGDAES--------------------------------VIDVPPPAGNSASLSLPLVLQSGISEPPQPLLPATAPSAPPPAPSLGPGSQPAAFGSP-------------------PALLQPPEVPVPHSTQFAANHQEFLPHPQAPPQTIVPGLSVVAGAP----ASAATVASAVAAPAPPQSTTEPLPAMVQTLPLGANSVLTNNPTITITPTPNTAILQSSLVMGEQNLQWILNGATSSPQNQEQIQQASKVEQVYFATAVPVASGTGSSVQQIGLSVPVIIIKQEEACQCQCACRDSAKERAAGRRKGCSSPPPPEPNPQPPDGPSLQLPP------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZBT4-1", "uniprot_id": "D3ZBT4_RAT", "id": "D3ZBT4-1", "name": "Metal regulatory transcription factor 1", "aln": "--------------------------------------------------------------------------------MGEHSPDDNIIFFKGEEDDLTPHDKMLRF------------------------------------------------------------------------------------------------------VDDNGLVPSSSGTVYDRTTVLIEQDPG--TLEDDEDDVQCGEHLPFLVEGEEGF-LIDQEAMSQGYVQHIISPDQIHLTINPGSTPMPRN-----IEGATLTLQSECPETKRKEVKRYQCTFEGCPRTYSTAGNLRTHQKTHRGEYTFVCNQEGCGKAFLTSYSLRIHVRVHTKEKPFECDVQGCEKAFNTLYRLKAHQRLHTGKTFNCESQGCSKYFTTLSDLRKHIRTHTGEKPFRCDHDGCGKAFAASHHLKTHVRTHTGERPFFCPSNGCEKTFSTQYSLKSHMKGHD----NKGTAYSALP---------------QHNGSEDTNHSLYLSELGLLSTDSELQENSSSTQDQDLSTISPAIIFESMFQNP-DDPAIQDDPLHTAALIDSFNGDAES--------------------------------VSDVPPPAGNSASLSLPLVLQPGISEPPQPLLPASTPSAPPPAPSLGPGSQPAAFGSP-------------------PALLQPPEVPVPHSTQFAANHQEFLPHPQAPPQTIVPGLSVVAGAP----ASAATVASAVAAPAPPQSTTEPLPAMVQTLPLGANSVLTNNPTITITPTPNTAILQSSLVMGEQNLQWILNGATSSPQNQEQIQQASKVEQVYFTTAVPVASSTGSSVQQIGLSVPVIIIKQEEACQCQCACRDSAKERAAGRRKGCSSPPPPEPNPQPPDGPSLQLPP------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14872-1", "uniprot_id": "MTF1_HUMAN", "id": "Q14872-1", "name": "Metal regulatory transcription factor 1", "aln": "--------------------------------------------------------------------------------MGEHSPDNNIIYFEAEEDELTPDDKMLRF------------------------------------------------------------------------------------------------------VDKNGLVPSSSGTVYDRTTVLIEQDPG--TLEDEDDDGQCGEHLPFLVGGEEGFHLIDHEAMSQGYVQHIISPDQIHLTINPGSTPMPRN-----IEGATLTLQSECPETKRKEVKRYQCTFEGCPRTYSTAGNLRTHQKTHRGEYTFVCNQEGCGKAFLTSYSLRIHVRVHTKEKPFECDVQGCEKAFNTLYRLKAHQRLHTGKTFNCESEGCSKYFTTLSDLRKHIRTHTGEKPFRCDHDGCGKAFAASHHLKTHVRTHTGERPFFCPSNGCEKTFSTQYSLKSHMKGHD----NKGHSYNALP---------------QHNGSEDTNHSLCLSDLSLLSTDSELRENSSTTQGQDLSTISPAIIFESMFQNS-DDTAIQEDPQQTASLTESFNGDAES--------------------------------VSDVPPSTGNSASLSLPLVLQPGLSEPPQPLLPASAPSAPPPAPSLGPGSQQAAFGNP-------------------PALLQPPEVPVPHSTQFAANHQEFLPHPQAP-QPIVPGLSVVAGAS----ASAAAVASAVAAPAPPQSTTEPLPAMVQTLPLGANSVLTNNPTITITPTPNTAILQSSLVMGEQNLQWILNGATSSPQNQEQIQQASKVEKVFFTTAVPVASSPGSSVQQIGLSVPVIIIKQEEACQCQCACRDSAKERASSRRKGCSSPPPPEPSPQAPDGPSLQLPAQTFSSAPVPGSSSSTLPSSCEQSRQAETPSDPQTETLSAMDVSEFLSLQSLDTPSNLIPIEALLQGEEEMGLTSSFSK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8JNP3-1", "uniprot_id": "A8JNP3_DROME", "id": "A8JNP3-1", "name": "", "aln": "MNDQEKQHQQQQQHYFHSEWKTTANSHGNSLSDSRDYDTNSSRNSLSGSPPVTSNCSSSGSLDFDRPLAQLLEPKLEADGLGIIHGDNYSIYGSQTAESTSGEQQVLNLGLTLDTGDAQATYGDLFGAQDQLTASQTHGHSQVVVSAAADNAFSLADQLTPLPITVIPITYHHTTENLSSSHSEVPLIASLSDITAQVFNLDDICFTLEYQFENQRLVQVQPPTVVSLSMVSSPNEAANPPINCDNDQGTGNSISRDSTSNSPAYFTIETSYVDEYDPNEPDEDEQLAHCIQPGVLHQDVDEEEVERQDENDQLMALAYESSDEALSRYRCNYENCYRSYSTIGNLRTHLKTHTGDYSFKCPEDGCHKAFLTSYSLKIHVRVHTKVKPYECEVSGCDKAFNTRYRLHAHLRLHNGETFNCEL--CQKCFTTLSDLKKHMRTHTQERPYKCPEDDCGKAFTASHHLKTHRRTHTGEKPYPCQEDSCQKSFSTSHSLKSHKKTHQRQLQNKGRKKRPLKTQQTKCSDQEQKDPQQEEQEEEEFIKEDQPEMTLLNPGSHCSETTSTDSGVVLQTLTPQDHLSNVFILQGNEPLILPETSQAYQLSYAAEEEIPSPWIDAGVLVSKPIIPMAPLTDACVALPTEMPSFVNLKPTFGNAVSGNMGDPQPETMDVDPTVETSLPTPTLELNQPNIEELLKQDSFENEEDMETESLLNDILMTIDNNSALLQATLQQASQVPSDASGLVELDIRDNKPTLKQITADAGICNCTNCKCDQTKSCHGGDCGAAAAQQTTRTGAPTTTTTTTTMNSSGGKRICGSVVPTKKVSKRETEMNQNIEDVALLLQNLASMSSGGSSGGGGGCCGGGAVKPAPSGGGCCGEPKAPKPVNAGCGCARPSAPSSGGCCGSGVASTPKPTGG-CCSGNQKPAPTATAASSPSCCCSGKGEVQEPPVISSASSAPAAAVKGNACTCKSPAEGVANGCCVVICIKTLQALRKVLTRRNLNLMLCPQQN---------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* *: *: . :. : .:::*.: .:.: ** .. ** . : * ::.. .:: ::*: .. . .. .: *: . :.: :. . :*: *:** : :. . * : . *:. : :.**:*.:*.* *:*** ****** *** *:*:* * ::** *********:******** **:**:*.**:***** ***:** ***.*:***** *.* *******:**:**** *:*::* .*.*****:******** ******:*: * .:.*:*:***.:***** * *: *** .* *.: .*: . .:: **...*. *.:*: .. *.*::* :..:* ::. * :. :: * : : : * . :: *. **:.* .: :. * . .:*: *.: : :* . .****.. ..: .. *:. *: : : * :.. : :.... .: : .. ...*..*.**.. .. . * . ** :. ::.** :.: ::.: . ::: :*:. :* ... .. .. . .* . .. *.. :.. : . ... *. . *. . **. * *.. ....** . ", "identical_positions": 190, "similar_positions": 243, "identity": "18.66%" }, { "cls_id": "homologset.agr.RGD:1308958", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZXD8-1", "uniprot_id": "TM245_RAT", "id": "D3ZXD8-1", "name": "Transmembrane protein 245", "aln": "MADRGGPAEEPSPRGSPRSEPRVPRTAGP----SETPRTAALALRFDKPIKQAFYNTGAVLFVCLCCGAAVLVYFILEAFLRPLLWAVLCGTFLHPFKSSLTRLGRLWLRRLHRAHTPIVLAALLLPLCFADYGVEALGEQALRRRRLLLLLG--AGGPLLYGLYCLG-SYLGVQVLLAHAGALICRGLDYFSSLWIWTLVVGYVLMVSFKWNASTQHYLRAVSIPVWMILLFHIASLAGSWRIPVFLVIVFLMSAGTLYEKQNEKESAGAELPGQVISMAASTLANLAISITGYESSSEDQPSDPSAEPTDKGEPPPAPSASSSSSSRSSPSSPSPTLGRQRPEMGTFLRKKKTSDIYFVSLVWAIIAVQLWLNLWIVQLLPVPVAVWIIKKLVIHFGVVGFLEKRCRAWWQVMESFLKERQEALAPWPITGLGKFLLKVDSKLWHWLNKKMIIWLEKMLDKIISIFIIFLLVIGTLLLALLLTAKVHQESVHMIEVTSSLINETLANHPEWANWLPEAQVVQRALNSAANNVYQYGREWITHKLHKILGDKVN-NTAVIEKQVLELWDRLYHSWFVKNVTHSGRHKGHKMHVSRQNSWLGDILD--------WQDIASFVHENIETFLSILESLWIVMSRNVSLLFTTVTTLLTILFYSGTALLNFVLSLIIFLTTLFYLLSSSDEYYKPVKWVISLTPLSQPGPSSNIIGQSVEEAIRGVFDASLKMAGFYGLYTWLTHTVFGINIVFIPSALAAILGAVPFLGTYWAAVPAVLDLWLTQGLGCKAVLLLVFHLLPTYFVDTAIYSDISGGGHPYLTGLAVAGGAYYLGLEGAIIGPILLCILVVASNIYSAMLVSPTNSMPTPSQTPWPAQTQRTFRDISEDLKSSVD---------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B1AZA5-1", "uniprot_id": "TM245_MOUSE", "id": "B1AZA5-1", "name": "Transmembrane protein 245", "aln": "MADRGGPAEAPSPRGSPRPESRAPRTVGP----GETPRTAALALRFDKPIKQAFYNTGAVLFVCLCCGAAVLVYFILEAFLRPLLWAVLCGTFLHPFKSSLTRLGRLWLRRLHRAHTPIVLAALLLPLCFADYGVEALGEQALRRRRLLLLLG--AGGPLLYGLYCLG-SYLGVQVLLAHAGALICRGLDYFSSLWIWTLVVGYVLMVSFKWNASTQRYLRAVSIPVWMILLFHIASLAGSWRIPVFLVIVFLMSVGTLYEKQNEKESAGAELPGQVISMAASTLANLAISITGYESSTEDQPSDPPTEPTDKGEPPPALSASSSSSSRSSPSSPSPTLGRQRPEMGTFLRKKKTSDIYFVSLVWAIIAVQLWLNLWIVQLLPVPVAVWIIKKLVIHFGVVGFLEKRCHAWWQVIECFLKERQEALAPWPIIGLGKFLLKVDSKLWHWLNKKMIIWLEKMLDKIISIFIIFLLVIGTLLLALLLTAKVHQESVHMIEVTSSLINETLANHPEWANWLPEAQVVQRALNSAANNVYQYGREWITHKLHKILGDKVN-NTAVIEKQVLELWDRLYHSWFVKNVTHSGRHKGHKMHVSRQNSWLGDILD--------WQDIASFVHENIETFLSILESLWIVMSRNVSLLFTTVTTLLTILFYSGTALLNFVLSLIIFLTTLFYLLSSSDEYYKPVKWVISLTPLSQPGPSSNIIGQSVEEAIRGVFDASLKMAGFYGLYTWLTHTIFGINIVFIPSALAAILGAVPFLGTYWAAVPAVLDLWLTQGLGCKAILLLVFHLLPTYFVDTAIYSDISGGGHPYLTGLAVAGGAYYLGLEGAIIGPILLCILVVASNIYSAMLVSPTNSMPTPNQTPWPAQTQRTFRDISEDLKSSVD---------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H330-2", "uniprot_id": "TM245_HUMAN", "id": "Q9H330-2", "name": "Transmembrane protein 245", "aln": "MADGGGPKDAPSLRSSPGPAPRVPRAVGPSGGGGETPRTAALALRFDKPIKQAFYNTGAVLFVCLCCGAAVLVYFILEAFLRPLLWAVLCGTFLHPFKSSLTRLGRHWLQRLHRAHTPIVLAALLLPLCFVDYGVEALGEQALRRRRLLLLLG--AGGPLLYGLYCLG-SYLGVQVLLVHAATLICRGLDYFSSLWIWTLVVGYVLTVSFKWNASTERYLRAVSIPVWIILLFHLASLAGSWRIPVFLVIVFLMSVGTLYEKQNGKESSGAELPGQVISMAASTLANLAISITGYESSSEDQPSTQPAEAVDRGESAPTLSTSPSPSS-PSPTSPSPTLGRRRPEIGTFLRKKKTSDIYFVSLVWAIVVMQIWLNLWIVQLLPVPIAVWILKKLVIHFGVVDFLEKRYHVWWGIIESFLKERQGALAPWPIVGLGKFLLKVDSKLWHWLNKKMIIWLEKMLDKIISIFIIFLLVIGTLLLALLLTAKVHQESVHMIEVTSNLINETLANHPEWANWLPEAQVVQRALNSAANNVYQYGREWITHKLHKILGDKVN-NTAVIEKQVLELWDRLYHSWFVKNVTHSGRHKGQKLHVSRQNSWLGDILD--------WQDIVSFVHENIETFLSILESLWIVMSRNVSLLFTTVTTLLTILFYSGTALLNFVLSLIIFLTTLFYLLSSSDEYYKPVKWVISLTPLSQPGPSSNIIGQSVEEAIRGVFDASLKMAGFYGLYTWLTHTMFGINIVFIPSALAAILGAVPFLGTYWAAVPAVLDLWLTQGLGCKAILLLIFHLLPTYFVDTAIYSDISGGGHPYLTGLAVAGGAYYLGLEGAIIGPILLCILVVASNIYSAMLVSPTNSVPTPNQTPWPAQPQRTFRDISEDLKSSVG---------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4K6B9-1", "uniprot_id": "A0A0B4K6B9_DROME", "id": "A0A0B4K6B9-1", "name": "Transmembrane protein 245", "aln": "-MNRSEPIPIRRDRSFDSVINRLLRMRSQ----------------NHESFRAAMYN----FLIAAGVAAFVAVCFILGPFVRPLLWAFLMGAVLFPFKRRLAESVNSWFHRLEVRDSNVLVSICLSPLEATEHCGRLLIGWLCEHWQLLLAGCGVAGCIKLLVLYAPKGFLLAIWHWITFSHGLFVQIIGFLNVYVLISLIVVYLSCVHFFWRPENSAHFVVAGQSMWIAVAGYLSSFLGALQVPVFLLVMTYVTASTAYHLQTLDDS------GSYLHRLQKLFDKNDFERSLSNFSICGRPGNEPLSPGLQSDVEDVSLSDTVDSTDTFDVKPETEVP------------SHQSDTFFKLLFYACLGTFLYRNVWMFILAAIPVILHLIYTVGEYTGITKFVCNKISEVYAALRFWAIEHHSAVLPLCLPGVLELNYKINTIVRDSL--------KASVESVTSILMIILMLLIIVFLSVFFCVNIYSETIEVAYLGKDLINKTITDRPELIDILPAN--MQSSIEDALDNAHHYGRRKIETYIDDWLADADKVHATKLKEQILEVWDRLIQYWIDFNKAGS--SYGPRVPTDALKSTFGEIVDNPELVLVAKQGIIGWAQSNTQTILEVAESLWHIIRTNMSMIMGVTGEILSLVLSGGQACIEFILDMIVFFTALFYLLSSSQEKYAPLQITKYLGYSS----SGIKIADALENSITVVLVSMFRCSTFTGLFTWLVHTVFGARIVFLPSALAAMLAAAPFLGSYWCAVPAFLELWLAQDRFYAGLILFLLQFFVPSSFETAIYADLKGG-HPYLNGLAIAGGMYWIGWQGAIFGPLMLCFFIGLFEVATLAMRSHQEPRNSTDEERTTSIPRRVNETVNDSIIKTNDNTDGKSVIEGKPVELKIVTKTKTFQLLNTKENQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . * *. * * . .:.:: *:** :::. .* * * *** .*:******.* *:.*.*** *:. . *::**. .: :::: * ** .:: . * .: :*** ** * **. *.: :..: *: : :.::. : :*:* *: * * *..... :: ... .:*: : :::*: *: ::****::: ::..* *. *. .:* *. : . : : :. : : * .:*. . .. :.: . :.. *: . .*.. : .: ** :* *.:* : :: *:*:. * .:*: : :: .: : *:. *: :: : :. : *:: *: * : *: :: *::: : . * : ::.: **::*:*::: ::*:::: .:::.*::.: : ..***:*::::** : ** :* :::.* :*.::***. * :.. *.* : ::: :::*:**:**** : *: * : * * :: .. :* :*:*:* *.* .:.:.* :*:*.: **** :: *:*::: .. :*:::: .* * ::*:*.:*:*:*:********:* * *:: . * * *. *.:::*::* *: : :: : * **:***.**:** .***:******:*.*.****:**.****.*:***:*. .::*:::::: . .:****:*:.** ****.***:*** *::* :***:**::**::: :: : : * :. :..: .: .:*. . :.:.: .: . ", "identical_positions": 223, "similar_positions": 340, "identity": "24.11%" }, { "cls_id": "homologset.agr.RGD:1308959", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U2P0-1", "uniprot_id": "DI3L1_RAT", "id": "Q5U2P0-1", "name": "DIS3-like exonuclease 1", "aln": "MLQKREKVLLLRTFQGRTLRIVREHYLRPSVPCNSPLCPQPATCRNDGKLLSAEVTHYVIPDWKVVQDYLEVLEFPELKGIIFMQTACQAVQHQRGRRQYNKLRNLLKDARHDCVLFANEFQQHCYLPREKGEAMEKWQTRSIYNSAVWYYHHCEDRMPIVMVTEDEEAIQQYGSETEGVFVISFKNYLDNFWPDLKAAHELCDSIIQSRRERESESQETHGKEYPEHLPLEVLEAGIKSGRYIQGILNVNKHRAQIEAFVRLQGASSKDSGLVSDILIHGSKARNRSIHGDVVVVELLPKSEWKGRTAALCENDSEDKASGESPSEPMPTGRVVGILQKNWRDYVVTFPSKEEVQSQGKNAQKILVTPWDYRIPKIRISTQQAEALQDFRVVVRIDSWETTSVYPNGHFVRVLGRIGDLEGEIATILVENSINVVPFSEAQMCEMPVNTAENPWKVSPKEEQERRDLRSTHLVFSIDPKGCEDVDDALSVRTLNNGN-LELGVHIADVTHFVAPNSYIDVEARTRATTYYLADRRYDMLPSILSADLCSLLGGVDRYAVSVMWELDKTSYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNFSIVDDIPEFKTLEEQNRQAKLEELVWAIGKLTDIARHIRAKRDRCGALELEGVEVRVQLDDKKNIHDLIPKQPLEVHETVAECMILANHWVAKKIWESFPHQALLRQHPPPHQEFFSELRECAKAKGFFIDTRSNKTLADSLDSANDPSDPLVNKLLRSMATQAMSNALYFSTGSCAEEEFHHYGLALDKYTHFTSPIRRYSDIVVHRLLMAAISKDKKVEIKENLFSNKNLEELCRHINNRNRAAQRSQKQSTELFQCMYFKDRDPETEERCVVDGIIYSIRTNGVLVFIPRFGIKGAAYLKNKDGLVISCGPEGSSEWKPGSLQRSQNKIISTTAGGQSVTFHLFDHVTVRISVQPSRCHSDMIRLEIVSNKPYMMPNTELCHQSSLLLKSELVKEVTRSVEEAQLAQEVKG---KVIEEEHQEYRQTKGRSLYTLLEEIRDLALLDVSDSYAM-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C0S1-1", "uniprot_id": "DI3L1_MOUSE", "id": "Q8C0S1-1", "name": "DIS3-like exonuclease 1", "aln": "MLQKREKVLLLRTFQGRTLRIVREHYLRPSVPCNSPLCPQPAACRNDGKLLAAEVTHYVIPDWKVVQDYLEVLEFPELKGVIFMQTACQAVQHQRGRRQYNKLRNLLKDARHDCVLFANEFQQHCYLPREKGEAMEKWQTRSIYNSAVWYYHHCEDRMPIVMVTEDEEAIQKYGSETEGVFVISFKNYLDNFWPDLKAAHDLCDSILQSRRERETESQETHGKEYPEHLPLEVLEAGIKSGRYIQGILNVNKHRAQIEAFVRLHGASSKDSGLVSDILIHGSKARNRSIHGDVVVVEMLPKSEWKGRTAALGENDSDDKASGESPSEPMPTGRVVGILQKNWRDYVVTFPSKEEVQSQGKNAQKILVTPWDYRIPKIRISTQQAEALQDFRVVVRIDSWEATSVYPNGHFVRVLGRIGDLEGEIATILVENSISVVPFSEAQMCEMPVNTPENPWKVSPKEEQERKDLRTTHLVFSIDPKGCEDVDDTLSVRTLNNGN-LELGVHIADVTHFVAPNSYIDVEARTRATTYYLADRRYDMLPSILSADLCSLLGGVDRYAVSVMWELDKTSYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNFSIVDDIPELKALDKQSQQAKLEELVWAIGKLTDIARHIRAKRDRCGALELEGVEVRVQLDDKKNIRDLIPKQPLEVHETVAECMILANHWVAKKIWESFPHQALLRQHPPPHQEFFSELRECAKAKGFFIDTRSNKTLADSLDSANDPKDPLVNKLLRSMATQAMSNALYFSTGSCAEEEFHHYGLALDKYTHFTSPIRRYSDIVVHRLLMAAISKDKKMEIKENLFSNKNLEELCRHINNRNRAAQRSQKQSTELFQCMYFKDRDAETEERCIADGVIYSIRTNGVLVFIPRFGIKGAAYLKNKDSLVISCGPEGSSEWKPGSLQRSQNKIISTTAGGQSVTFHLFDHVTVRISVQASRCHSDTIRLEIVSNKPYMIPNTELCHQSS-LLKSELVKEVTRSVEEAQLAQEVKG---KVIQEEHQEYCQTKGRSLYTLLEEIRDLALLDVSDSCAM-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TF46-1", "uniprot_id": "DI3L1_HUMAN", "id": "Q8TF46-1", "name": "DIS3-like exonuclease 1", "aln": "MLQKREKVLLLRTFQGRTLRIVREHYLRPCVPCHSPLCPQPAACSHDGKLLSSDVTHYVIPDWKVVQDYLEILEFPELKGIIFMQTACQAVQHQRGRRQYNKLRNLLKDARHDCILFANEFQQCCYLPRERGESMEKWQTRSIYNAAVWYYHHCQDRMPIVMVTEDEEAIQQYGSETEGVFVITFKNYLDNFWPDLKAAHELCDSILQSRRERENESQESHGKEYPEHLPLEVLEAGIKSGRYIQGILNVNKHRAQIEAFVRLQGASSKDSDLVSDILIHGMKARNRSIHGDVVVVELLPKNEWKGRTVALCENDCDDKASGESPSEPMPTGRVVGILQKNWRDYVVTFPSKEEVQSQGKNAQKILVTPWDYRIPKIRISTQQAETLQDFRVVVRIDSWESTSVYPNGHFVRVLGRIGDLEGEIATILVENSISVIPFSEAQMCEMPVNTPESPWKVSPEEEQKRKDLRKSHLVFSIDPKGCEDVDDTLSVRTLNNGN-LELGVHIADVTHFVAPNSYIDIEARTRATTYYLADRRYDMLPSVLSADLCSLLGGVDRYAVSIMWELDKASYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNLSVVDDIPEFKDLDEKSRQAKLEELVWAIGKLTDIARHVRAKRDGCGALELEGVEVCVQLDDKKNIHDLIPKQPLEVHETVAECMILANHWVAKKIWESFPHQALLRQHPPPHQEFFSELRECAKAKGFFIDTRSNKTLADSLDNANDPHDPIVNRLLRSMATQAMSNALYFSTGSCAEEEFHHYGLALDKYTHFTSPIRRYSDIVVHRLLMAAISKDKKMEIKGNLFSNKDLEELCRHINNRNQAAQHSQKQSTELFQCMYFKDKDPATEERCISDGVIYSIRTNGVLLFIPRFGIKGAAYLKNKDGLVISCGPDSCSEWKPGSLQRFQNKITSTTTDGESVTFHLFDHVTVRISIQASRCHSDTIRLEIISNKPYKIPNTELIHQSSPLLKSELVKEVTKSVEEAQLAQEVKV---NIIQEEYQEYRQTKGRSLYTLLEEIRDLALLDVSNNYGI-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2RV18-1", "uniprot_id": "DI3L1_DANRE", "id": "A2RV18-1", "name": "DIS3-like exonuclease 1", "aln": "-MIKTEKILHLNSSKGRKVRVVREHYMREQVPCGSSLC--QADCQNVGKVLSRDVTHYVVPDVGVVRDFLEILELRELQGIVLTQTAYQTVQHTRGRRHYNRLRSLLKDPRHDCVLFANEFQQYSYCPREKGESQDKWHTRNVYNAAVWYYNHLAGLQPVVMITEDRDAISEFSASNSGVFVISTQEYLLGFWPDLQAAHDLYHSIAQTLQERENDGAE---KVYTEHLPAEVLEAGIKSGRYIQGILSVNKHRAQHEAFVRYEGSASKNTELNSDVLINGAKHRNRAVHGDVVVIELLPRNEWKGRTMALTEGQGEERPLEDTQSQPMPTGRVVEILQRNWRDYVVTLPPFEEMQSQSRNSQKILVVPWDYRIPKIRISTQQAEALQDQRVIVRLDSWESTSVYPNGHFVRVLGKSGELETEIQTILVENCIHVPPFSEAQLREMPVNTEENPWQMDSNEVSSRRDLRDSHLVFSIDPKGCEDVDDTLSVRTLPGGKRLELGVHIADVTHFVREGSLTDLEARSRATTYYLADRRYDMLPAVLSADLCSLLGGVDRYAMSVLWELDAETLEVCSVWFGRTLIRSSYQLHYELAQSLLNG---EEVEVPELNPLKGSQRDQKMSELLQALETLTRVARHLRAQRDKGGALELEGVEVRAQLDEEKNITALVPKQPLEVHETVAECMIYANHWVARKIQESFPHHALLRHHPPPKQEFFNHLIDSAKAHGFSIDTRSNRALADSLERAVDPRDPLVNRLLRMMATQAMSNALYFSTGSCPEEQYYHYGLALARYTHFTSPIRRYADVIVHRLLMAAVQLEKDESPSKALACNKELEELAQHINNKNRAAQHSQKQSIELFQCMYFRDKDSHTDERCVADAVIYAVRANGFLAFVPQYGLKGAVYLKDREGQVISVDGDGKCEWKPGTLQKYSDKIITSTSTG-THTFYLFNHVTVRISVEPSRCHADSLNLELISNKPHCAVQPE--SQPAGGGRSGLVEEVVRWAEEASLQAEEQRGRKPKLSKEEKQFRQSKTPNLYVLLQEISELALMDLSICQITNSEEQTCTVSS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * **:* *.: :**.:*:*****:* *** *.** * * : **:*: :*****:** **:*:**:**: **:*::: *** *:*** ****:**:**.****.****:******** .* ***:**: :**:**.:**:*****:* . *:**:***.:**.::.:...*****: ::** .*****:***:* .** *: :***.:. * * *.**** *****************.******* ***** .*::**:: * **:**:* * ***::******:*:**:.****** ** *.: :::. :: *:******** ***:********:*. **:***.:*:*****.*****************:*** **:**:****:**************: *:** ** ******.* * ******: ****** *.**::..:* ..*:*** :****************:****** .*: ************** .* *:***:****************::****************:*::**** : *: .**:***:***:*:*.** **.**:* ::**:: *. ..:: *:.**: *: .** :***:**:** ********** .***::*** *:**************** ******:** *****:****:****:****..* :.***:** ******::*****: * ** **:**:*** *****************.**:::****** :***********:*::********:. :*. . . * .**:****.:****:*:***:***** ********:*:*. *:***: *.:**::*:**.* *:*::*:***.***:::. *** . :. .*****:**: .:** ::*: * : **:**:*******::.****:* :.**::****: :.* *.: :* **:**.: .***.* * : :.:* ::: *:* .**.**:** :***:*:* ", "identical_positions": 651, "similar_positions": 257, "identity": "60.9%" }, { "cls_id": "homologset.agr.RGD:1308961", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WTY1-1", "uniprot_id": "PDCD7_MOUSE", "id": "Q9WTY1-1", "name": "Programmed cell death protein 7", "aln": "MALPPFFAQSRQGPPPPQPPPSAPFGCPPPPLPSPAFPPPLPQRPGPFPGASAPFLQPPLALQPRAPAEASRGGGG---GGAFFPVPPPPLPPPPPQCRPFPGPDAVERPRPPPPGPGPPWSPRWAEAPPPP-DVLGDAALQRLRDRQWLEAVFGNPRRPGGLRTPRTPAGPSLGEVRARLRSALRLVRRLRSLGQSLREAEADGAAWASLHAQAAPLRAELAERLQPLRQAAYVGEARRRLERVRRR-VRVRERARDRRLS-GRRGAQRTEREQEIDRWRVKCVQEVEEKKRDEELKAAADGVLAEVRKKQSDTKRMVDILRALEKLRKLRKEAAARKGVCPPASADETFEHHLQRLRKLIKKRSELYEAEERALRVMLEGEQEEERRRELEKKQRKEKEKLLLQKREIESKLFGDPDEFPLAHLLQPFRQYYLQAEHSLPALIQIRHDWDQYLVPSDHPKGNSVPQGWVLPPLPSNDIWATAIQLH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4ACM6-1", "uniprot_id": "D4ACM6_RAT", "id": "D4ACM6-1", "name": "", "aln": "MALPPFFAQSRQGPPPPQPPPSAPFSCPPPPLPSPVFPPPLPQRPGPFPGASAPFLQPPIALQPRASAEASRGGGGSGGGGAFFPVPPPPLPPPP-QCRPFPGPDVVERPRPPPPGPGPPWSPRWAEAPPPP-DVLGDAALQRLRDRQWLEAVFGNPRRPVGPRTPRTPAGPSLGEVRARLRAALRLVRRLRSLGQSLREAEADGAAWVSLHAQAAPLRAELAERLQPLAQAAYMGEARRRLERVRRRRLRLRERARERETEREAEAAQATEREQEIDRWRMKCVQEVEEKKREQELKAAADGVLAEVRKKQSDTKRMVDILRALEKLRKLRKEAAARKGVCPPAAADETFEHHLQRLRKLIKKRSELYEAEERALRVMLEGEQEEERRRELEKKQRKEKEKLLLQKREIESKLFGDPDEFPLAHLLEPFRQYYLQAEHSLPALIQIRHDWDQYLVPSDHPKGNSIPQGWVLPPLPSNDIWATAVQLH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N8D1-1", "uniprot_id": "PDCD7_HUMAN", "id": "Q8N8D1-1", "name": "Programmed cell death protein 7", "aln": "MALPPFFGQGRPGPPPPQPPPPAPFGCPPPPLPSPAFPPPLPQRPGPFPGASAPFLQPPLALQPRASAEASRGGGG---AGAFYPVPPPPLPPPPPQCRPFPGTDAGERPRPPPPGPGPPWSPRWPEAPPPPADVLGDAALQRLRDRQWLEAVFGTPRRAGCPVPQRTHAGPSLGEVRARLLRALRLVRRLRGLSQALREAEADGAAWVLLYSQTAPLRAELAERLQPLTQAAYVGEARRRLERVRRRRLRLRERAREREAEREAEAARAVEREQEIDRWRVKCVQEVEEKKREQELKAAADGVLSEVRKKQADTKRMVDILRALEKLRKLRKEAAARKGVCPPASADETFTHHLQRLRKLIKKRSELYEAEERALRVMLEGEQEEERKRELEKKQRKEKEKILLQKREIESKLFGDPDEFPLAHLLEPFRQYYLQAEHSLPALIQIRHDWDQYLVPSDHPKGNFVPQGWVLPPLPSNDIWATAVKLH", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*******.*.* *********.***.*********.***********************:******.********* .***:*********** *******.*. ******************.****** **********************.***. . ** ************ *********.*.*:***********. *::*:************** ****:************* :*:*****:*. . ..*: .**********:***********::**********:******:********************************:***** ************************************:*************:************************:************************************ :******************::**", "identical_positions": 419, "similar_positions": 44, "identity": "85.86%" }, { "cls_id": "homologset.agr.RGD:1308962", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5YBG7-1", "uniprot_id": "A0A8I5YBG7_RAT", "id": "A0A8I5YBG7-1", "name": "Pyridoxal phosphate homeostasis protein", "aln": "MLRGGSMTAELGVGLALRAVNERVQQSVARRPR----GLPAIQPRLVAVSKTKPTEMVIEAYGHGQRTFGENYVQELLEKASNPTLLSSCPEIKWHFIGHLQKQNVNKLMAVPNLSMLETIDSVKLADKVNSSWQKKGSP--ERLKVMVQINTSGEDSKHGLL-PSETVAVVEHIK-ASCPNLEFVGLMTIGSFGHDLSQG-PNPDFQRLLSLRQELCEKLGLPVEQVELSMGMSVDFQHAIEVGSTNIRVGSTIFGERDYSKKPAPDKTTIDLTASVPLVQGQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z2Y8-1", "uniprot_id": "PLPHP_MOUSE", "id": "Q9Z2Y8-1", "name": "Pyridoxal phosphate homeostasis protein", "aln": "MLRGGSMTAELGVGFALRAVNERVQQSVARRPR----DLPAIQPRLVAVSKTKPADMVIEAYGHGQRTFGENYVQELLEKASNPKILSSCPEIKWHFIGHLQKQNVNKLMAVPNLSMLETVDSVKLADKVNSSWQKKGPT--EPLKVMVQINTSGEDSKHGLL-PSETIAVVEHIK-ASCPSLEFVGLMTIGSFGHDLSQG-PNPDFQRLLTLRRELCEKLGIPVEQVELSMGMSMDFQHAIEVGSTNVRIGSTIFGERDYSKKPALDKT-ADAKASVPLVQGH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O94903-1", "uniprot_id": "PLPHP_HUMAN", "id": "O94903-1", "name": "Pyridoxal phosphate homeostasis protein", "aln": "MWRAGSMSAELGVGCALRAVNERVQQAVARRPR----DLPAIQPRLVAVSKTKPADMVIEAYGHGQRTFGENYVQELLEKASNPKILSLCPEIKWHFIGHLQKQNVNKLMAVPNLFMLETVDSVKLADKVNSSWQRKGSP--ERLKVMVQINTSGEESKHGLP-PSETIAIVEHIN-AKCPNLEFVGLMTIGSFGHDLSQG-PNPDFQLLLSLREELCKKLNIPADQVELSMGMSADFQHAVEVGSTNVRIGSTIFGERDYSKKPTPDKCAADVKAPLEVAQEH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VA97-1", "uniprot_id": "Q9VA97_DROME", "id": "Q9VA97-1", "name": "Pyridoxal phosphate homeostasis protein", "aln": "MLR--RTMAEFDVKAGLQHVLKRIDEVLLQRPK----EVQAARPLLVAVSKTKPAEAVIEAYEGGQRDFGENYVQELEEKSRHPDILAKCPDIRWHFIGHMQSNKINKILSVPNLHMIQTVDSEKLATKLDAAWSKRQPTPEEPLQVLIQINTSGEDVKSGIE-AKDAPALYQYIK-SNLKHLNLMGIMTIGAFGFDYSNG-PNPDFVSLMQVHRSICEAHSLAPDSVLVSMGMSNDFDKAIEMGSTVVRVGSSIFGHR---------------AAKV------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38197-1", "uniprot_id": "PLPHP_YEAST", "id": "P38197-1", "name": "Pyridoxal phosphate homeostasis protein", "aln": "MSTG--ITYDEDRKTQLIAQYESVREVVNAEAKNVHVNENASKILLLVVSKLKPASDIQILYDHGVREFGENYVQELIEKAK---LLP--DDIKWHFIGGLQTNKCKDLAKVPNLYSVETIDSLKKAKKLNESRAKFQPD-CNPILCNVQINTSHEDQKSGLNNEAEIFEVIDFFLSEECKYIKLNGLMTIGSWNVSHEDSKENRDFATLVEWKKKIDAKFGT---SLKLSMGMSADFREAIRQGTAEVRIGTDIFGARPPKN-----------EARII-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : . * : : : : ..: * : *:.*** **:. : * * * ********* **: :*. :*:***** :*.:: :.: **** ::*:** * * *:: : : . : : :***** *: * *: : : :.: . ::: *:****::. . .:. * ** *: :..: . .: :***** ** .*:. *:: :*:*: *** * * : ", "identical_positions": 74, "similar_positions": 75, "identity": "26.06%" }, { "cls_id": "homologset.agr.RGD:1308964", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZQN6-1", "uniprot_id": "D3ZQN6_RAT", "id": "D3ZQN6-1", "name": "SH3 and cysteine-rich domain-containing protein 3", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTEKEVVESPQPPFPGET-----------------------PQSGLQRLKQLFKKGSPETTEMEPPPEPQANGEAVGAGGGPIYYIYEEEEEE------------------------------------------------------------------------------------------EEEEE-PPPEPPKLVNDKPHKFKDHFFKKPKFCDVCARMIVLNNKFGLRCKNCKTNIHEHCQS------------------------------------------------------YVEMQKCFGKIPPG---FHRAYSSPLYSNQQYAC---VSAANRNDPVFETLRVGVIMANK---------------ERKKGQADKKNPLAAMMEEEPESARPEEGKSQ--------------DGNDAEKDKKAEKKTPD-DKNKQPG--------------------------------------------------------------------------FQQSHYFVALYRFKALEKDDLDFPPGEKITVIDDSNEEWWRGKIGEKVGFFPPNFIIRVRAGERVHRVTR-SFVGNREIG-QITLKKDQIVVQKGDEAGGYVKVYTGRK-VGLFPTDFLEEI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BZ71-1", "uniprot_id": "STAC3_MOUSE", "id": "Q8BZ71-1", "name": "SH3 and cysteine-rich domain-containing protein 3", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTEKEVVESPQPPFPGET-----------------------PQSGLQRLKQLFKKGSPETAEMEPPPEPQANGEAVGAGGGPIYYIYEEEEEE------------------------------------------------------------------------------------------EEEEE-PPPEPPKLVNDKPHKFKDHFFKKPKFCDVCARMIVLNNKFGLRCKNCKTNIHEHCQS------------------------------------------------------YVEMQRCFGKIPPG---FRRAYSSPLYSDQQYA----VSAANRNDPVFETLRVGVIMANK---------------ERKKGQADKKNPLAAMMEEEPESARPEEGKSQ--------------DGNNAEKDKKAEKKTPD-DKNKQPG--------------------------------------------------------------------------FQQSHYFVALYRFKALEKDDLDFPPGEKITVIDDSNEEWWRGKIGEKVGFFPPNFIIRVRAGERVHRVTR-SFVGNREIG-QITLKKDQIVVQKGDEAGGYVKVYTGRK-VGLFPTDFLEEI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96MF2-1", "uniprot_id": "STAC3_HUMAN", "id": "Q96MF2-1", "name": "SH3 and cysteine-rich domain-containing protein 3", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTEKEVLESPKPSFPAET-----------------------RQSGLQRLKQLLRKGSTGTKEMELPPEPQANGEAVGAGGGPIYYIYEEEEEE------------------------------------------------------------------------------------------EEEEEEPPPEPPKLVNDKPHKFKDHFFKKPKFCDVCARMIVLNNKFGLRCKNCKTNIHEHCQS------------------------------------------------------YVEMQRCFGKIPPG---FHRAYSSPLYSNQQYACVKDLSAANRNDPVFETLRTGVIMANK---------------ERKKGQADKKNPVAAMMEEEPESARPEEGKPQ--------------DGN-PEGDKKAEKKTPD-DKHKQPG--------------------------------------------------------------------------FQQSHYFVALYRFKALEKDDLDFPPGEKITVIDDSNEEWWRGKIGEKVGFFPPNFIIRVRAGERVHRVTR-SFVGNREIG-QITLKKDQIVVQKGDEAGGYVKVYTGRK-VGLFPTDFLEEI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DBR6-1", "uniprot_id": "STAC3_DANRE", "id": "Q6DBR6-1", "name": "SH3 and cysteine-rich domain-containing protein 3", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAQYDQLEDKDSLDIHDN--PPAPEN---VVKEDDNTVYFVYDEEVEE------------------------------------------------------------------------------------------EEAPPPPTPEPIVQVNDKPHKFKDHYCKKPKFCDVCARMIVLNNKFALRCKNCKTNIHHSCQS------------------------------------------------------YVQFQRCFGKIPPG---FRRAYSSPLYDQEINNP----GQQNRTDPVFDTLRVGVIMANK---------------ERKKGSEDKKNMMMMMMEEE-EAQQPKEDEEG--------------AEGKQDGDKKDKTATDDKNKKQQQT--------------------------------------------------------------------------FSQSHYYMALYRFKAIEKDDLDFHPGDRITVLDDSNEEWWRGKIGEKTGYLPMTYIIRVRAGERVYKVTR-SFVGNREMG-QITLKKDQIVVKKGEEVNGYLKVSTGRK-LGFFPADLLHEL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KEV7-1", "uniprot_id": "A0A0B4KEV7_DROME", "id": "A0A0B4KEV7-1", "name": "", "aln": "MGISAHAAPASFWNHPRRIRRTPTSDRDGVDQCRPWICRRKDRRPAHPAANRPPESRVCGPSSTFRWDDWAAPAPRTRERATDCARMCMCTSRIPYSVARICARTTSMHSSRPASRSSSFIRRPLTRRQRMAVGGVTRRLWRTMRVYTIHQGRGVRRARAAQAVAAYLRDRRARIGKGWPAQGHGVRISATEQWADKPVVRRPGDPTRRVAAGAVPVLAERLPKVTGSSVKSSSGRRSRRRRIFGWRGPRGGSLSPQGGSMASYNGVLKDYSHSSLNEAFKSQNNVNFKLIKTVSDFSETLSRLYEEHATALQVAVSNYRKKNAELRKERPACHLAIFQAWETFLQEVETDSQACNDVASVLSRQVSRPMLDKSFHRKVQSRKIFTHRESFETIIAKTEEKLSKCRVDYKQCHLAHRQNPSQHSLTEYIDAHNAYVQQLHATNGMLEAYHTDTLPQQMQELEEIHNDLVAIVSDSLMQGAEVIAGKANDQAKRYNSLSNQCAAVSPQQDLVNFVRLLAQPSQAQKIPRRLFASPQAEVGEEAGDHNEMTPCLRNELVFDRHSTLSQRSALESLKREAIELELQIRQLQDSIEALNRTQTRGIEGQLYNKVNELQEDLSMKKFDLRAKQIHLAAIRAQKDLFVSKVEPTSPRNERKFSAATAPSMKTKWLKAFKSLKPAGSGSAQQADSQPPRQNQMYHAVSTVLTLRRNGASSTASEPLRPNLDGSHHLQEYTYKKITACDVCSQILRGHTRQGLRCRICKLNAHGDCAPNLPRCQPKQKLLRRQKSTSELENRVDIEEETGADKSVQAKQMDGSVAGGSALPVPVLSERELGRAPPPDIPIVSVSELALQEQQQQQQQQQQQHQQQQRSLASVAQAAAVRAGRGVRPPPVAMPILGVQLQQQELQQQRGGLPVPSQDISSSSAPHSPRRQKLNLRMKSLSLDSPESSELHGQFRRRTQLPGTGASTSAGSGYYHGGSGGHLEHSTPPSNNSRLHSPSSPSHPGRKLLYATRGMRGGSVDLPDEMEKSQSSASTSPCLSPKTHRLLPTNLYVIIYNFKARHADELDLKAGYKVTVIDNSDPDWWKGKVLGRVGYFPSKYCVRLNANEKPLQVTHNLQVSDSERGENLTLLRDQIVIQTGDEVNGMVMIRAAEHGQGYCPIKYLQEVXQPEEDEPPSDERDRPHKSSMQTSSSRTADKTKRRIRIVVSENHNVAASSVAPAPPTTAFNTTTHHQIPRESDIETKRLNIDYGDEGSADWDKDREVLILSGRRNKNDKNWENWERIREQKLEKMKGICFESYRQSKRDKLLQAKPRPKQLDSTWYTDNIYSNRSDDMDEDYVPDCLKYGPFRTLRDIHELDEKSGVTEERRVEGEGSPGYGLHRSKSCKEFQYPKSQSWCFEGNVFEAGGGVASGSGSSSGAPPPTTSILKNRAGVPKSYSFSATTKTMPFDIIDYELPPVSNTRREKKEALRRNMNALCSSSLDRCCARDQCTSARCLLEDIYPGSRMRPRTTGAGSNRNLSAADWLFEERAGRQRTPAAPTVICCCSAAEDCCCHRQRQQQPPLPARPRSRPLCPGHHPAAEEEEHMHCRYDTDLEHFIRAERERLMLQDKFLDDDERYLAAAPAPRSPGRRYPAGNYHRPPRSKSLLEMQPPTILYDEDTCSDTTEIDLEDFNIDLEKYWEQLDKPPSPINMDMRRNMHSSLKVKNVNVRCYNNGQPIDLHDREHERLMIKKSLLEGMPSPPQLDSSESSTNAGGYPFFDTAPAVAPAPAFHHHPAYGQPQGYGHKVYPTVDTLPSYQYNNFYPEHSHPTVGSVLTQQPTAGIHHPSAGGHSALSLINNIFSIYKPNKYSPENCQMNYESKPEPCKKMNVPSTHRPLGAAAHPYPAHDYMHSSMKRPLLVSADQPHFKIIPEKTGLKISPLLSYEDYGGGGGGEKAHHRLTSTARPLMLPHXWCWTFPWYGNGNGNGNYC", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .: : . : . . . . : : : : .: ...** * .*::::: ** . ****:::: :.: .***: ** * * * . * :: :*: ** : . . .* .:: :: .: .. :...: *.: ::: :::. : :: .: *.. . . . : : .. . . . : :: :: :*.*** . *:**: .* ::**:*:*: :**:**: :.*::* .: :*:.*.*: :**: *.: * * ::** :****::.*:*..* : : :..: * * . *.*: ", "identical_positions": 64, "similar_positions": 136, "identity": "3.25%" }, { "cls_id": "homologset.agr.RGD:1308965", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9DBH5-1", "uniprot_id": "LMAN2_MOUSE", "id": "Q9DBH5-1", "name": "Vesicular integral-membrane protein VIP36", "aln": "MAAEAWLWRWGWGWGQRCPGRPGLPGPGPSPTTFLHLLLLLG--PVAADITDGNSEHLKREHSLIKPYQGVGS--------SSMPLWDFQGSTMLT-SQYVRLTPDERSKEGSIWNHQ---PCFLKDWEMHVHFKVHGTGKKNLHGDGIALWYTRDRLVPG------------------------PVFGSKDNFHGLAIFLDTYPNDE-TTERVFPYISVMVNNGSLS--YDHSKDG-----------RWSELAGCTADFRNRDHDTFLAVRYSRGRLTVMTDLEDKNEWKNCIDITGVRLP-----TGYYFGASAGTGDLS---DNHDIISIKLFQ----------------------------------LTVERTPEEESIDWTKIEPGVNFLK----------------------------------------------------------------------------SPKDNVDDPTGNFRNGPLTGWRVFLLLLCALLGVVVCAVVGAVVFQKRQERNKRFY-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7FPK8-1", "uniprot_id": "F7FPK8_RAT", "id": "F7FPK8-1", "name": "", "aln": "MAAEAWLWRWGWGWGQRCPGRPGLPGPGPGPTTFLHFLLLLG--LVAADITDGNSEHLKREHSLIKPYQGVGS--------SSMPLWDFQGSTMLT-SQYVRLTPDERSKEGSIWNHQ---PCFLKDWEMHVHFKVHGTGKKNLHGDGIALWYTRDRLVPG------------------------PVFGSKDNFHGLAVFLDTYPNDE-TTERVFPYISVMVNNGSLS--YDHSKDG-----------RWSELAGCTADFRNRDHDTFLAVRYSRGRLTVMTDLEDKNEWKNCIDVTGVRLP-----TGYYFGASAGTGDLS---DNHDLISIKLFQ----------------------------------LTVERTPEEESIDWTKIEPGVNFLK----------------------------------------------------------------------------SPKDNVDDPTGNFRGGPLTGWRVFLLLLCALLGIIVCAVVGAVVFQKRQERNKRFY-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q12907-1", "uniprot_id": "LMAN2_HUMAN", "id": "Q12907-1", "name": "Vesicular integral-membrane protein VIP36", "aln": "MAAEGWIWRWGWGR--RCLGRPGLLGPGPGPTTPLFLLLLLG--SVTADITDGNSEHLKREHSLIKPYQGVGS--------SSMPLWDFQGSTMLT-SQYVRLTPDERSKEGSIWNHQ---PCFLKDWEMHVHFKVHGTGKKNLHGDGIALWYTRDRLVPG------------------------PVFGSKDNFHGLAIFLDTYPNDE-TTERVFPYISVMVNNGSLS--YDHSKDG-----------RWTELAGCTADFRNRDHDTFLAVRYSRGRLTVMTDLEDKNEWKNCIDITGVRLP-----TGYYFGASAGTGDLS---DNHDIISMKLFQ----------------------------------LMVEHTPDEESIDWTKIEPSVNFLK----------------------------------------------------------------------------SPKDNVDDPTGNFRSGPLTGWRVFLLLLCALLGIVVCAVVGAVVFQKRQERNKRFY-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VCC2-1", "uniprot_id": "Q9VCC2_DROME", "id": "Q9VCC2-1", "name": "L-type lectin-like domain-containing protein", "aln": "-----------------------MTKPTREHCSLALLALLVAPFVVLGEDMPREPDYMKREHSLVRPFQGVG---------VILPHWDFLGNTMVT-SNYIRLTPDLQSKSGALWNYS---PVMTRNWEVHVGFKVHGKG-TELFGDGFAIWYTKERMQTG------------------------PVFGSKDHFSGLAIILDTYSNHNGPHNHQHPYLSAMVNNGSWS--YDHDRDG-----------THTQLAGCEVRFRNVEYETLVSIRYENDILSVSTDLENRNEWKNCFVVANVELP-----TGYHFGMSATTGDLS---DNHDIHSFKFYD----------------------------------LDLNVN-HDEIIRRSNIIPNAKTFE----------------------------------------------------------------------------PPREHKEDP----KPG-MSNAKIFFILLFVVVVAAAVAIFAISYFKDRNAR-KRFY-----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12396-1", "uniprot_id": "EMP46_YEAST", "id": "Q12396-1", "name": "Protein EMP46", "aln": "--MTTRKTASSLQLLGKITGTKAGTKQKKMNFINGLIWLYMCVWMVHGKVTQKDELKWNKGYSLPNLLEVTDQQ-------KELSQWTLGDKVKLE-EGRFVLTPGKNTK-GSLWLKP---EYSIKD-AMTIEWTFRSFGFRGSTKGGLAFWLKQ-GNEGDS---------------------TELFGGSSKKFNGLMILLRLDDKLG-------ESVTAYLNDGTKD--LDIE--------------SSPYFASCLFQYQDSMVPSTLRLTYNPLDNHLLKLQMDN---RVCFQTRKVKFMG---SSPFRIGTSAINDASK---ESFEILKMKLYDGVIEDSLIPNVNPMGQPRVVTKVINSQTGEESFREKMPFSDKEESITSNELFEKMNKLEGKIMANDIDPLLRKMNKIVENERELIQRLRPLLDLKKT--------------AISDD--SFQDFLSMNANLDRLIKEQEKIRQDAKLYGKQTKGHDEIFSKISVWLALLIFIMITLAYYMFRINQDIKKVKLL----------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P43555-1", "uniprot_id": "EMP47_YEAST", "id": "P43555-1", "name": "Protein EMP47", "aln": "--MMMLITMKSTVLLSVFT----------------VLATWAGLLEAHPLGDTSDASKLSSDYSLPDLINAR----------KVPNNWQTGEQASLE-EGRIVLTSKQNSK-GSLWLKQ---GFDLKD-SFTMEWTFRSVGYSGQTDGGISFWFVQDSNVPRD---------------------KQLYNGPVN-YDGLQLLVDNNGPLG-------PTLRGQLNDGQKP--VDKTKI------------YDQSFASCLMGYQDSSVPSTIRVTYDLEDDNLLKVQVDN---KVCFQTRKVRFP----SGSYRIGVTAQNGAVNNNAESFEIFKMQFFNGVIEDSLIPNVNAMGQPKLITKYIDQQTGKEKLIEKTAFDADKDKITNYELYKKLDRVEGKILANDINALETKLNDVIKVQQELLSFMTTITKQLSSKPPANNEKGTSTDDAIAEDKENFKDFLSINQKLEKVLVEQEKYREATKRHGQDGPQVDEIARKLMIWLLPLIFIMLVMAYYTFRIRQEIIKTKLL----------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P36137-1", "uniprot_id": "UIP5_YEAST", "id": "P36137-1", "name": "Protein UIP5", "aln": "--------------MSRDVRAEKLAISLLILSLFLIFQLVAEIYLNNGDQYHTETSPFTRGRSHVTRVPNHDASLSIPFLDKINQFWHVGGATQIRNIQSIKLTQDRDQDKHGLVLSNGIGDNTINDFEIVFTFRISHDPTTQLTGDGMCFAITPENGFLTQNLQSSYAKKQYMMNSQGVIADNTDLMGFPKNLPGLFIVLDTYRNQG-HDHKEVPFMDVFINVAPESDWYDINSDGELSTSLRLNSRGHIKLKKNALWNRVTKLRIIYLESISFLKIDVQYAKEGNYWIELFQTTENLYLPKNMHTGQRYIGCSALNGQLTETVELLDVSTSEFHWN----------DMDASIEDTYDYAKEAELFLEQEFGEVLDREPDEFTKWKMIKAQPNIKTGSQS-----------------------------------------------------------------------AEQKTSNNPHSRLFKVVLTIWHYSEILLLIMGIYLFSACIRVFQRRFKKIRSRRKRAGSHSVGLLPM", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . * * . : . ** . .: .: . . : . .*:.: * . ** :.: : :* . * : : . : .. . : : :* :* .. . : :: . ::. . : : :: .: .. : . : : . : .: : ", "identical_positions": 12, "similar_positions": 65, "identity": "2.23%" }, { "cls_id": "homologset.agr.RGD:1308966", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q64355-1", "uniprot_id": "EFS_MOUSE", "id": "Q64355-1", "name": "Embryonal Fyn-associated substrate", "aln": "MAIATSAQLARALYDNTAESPQELSFRRGDVLRVLQREGAGGLDGWCLCSLHGQQGIVPANRVKLLPAGPAPKPSLCPASPTQPG-SSCPTPERGCEEQEVYVIPPPARPCSASGLPARSCSPSSDSIYKVPRGNGMQLTASRDVAEVYDVPPNILRAPSSCPYDSPASFSCPVAPVVPQPPREDEAPYDVPLALKPPAELERDPEWEGGREPGPPLYAAPSNLKRASALLNLYEAPEELLANGESRDADEGIYDVPLLGPE-PPSPEPPVASSSTDLDTVAQLPTRSSPPQHRPRLPSTESLSRRPLPALPVSEAPAPSPAPSPAPGRKGSIQDRPLPPPPPCLPGYGGLKPEGDPECREVANDPAGPHNEYEGIPMAEEYDYVHLKGVDTAQGSRPLDKAFPVDPELLERGLAERKEALSPEEPLVLSTGDLQLLHFYAGQCQSHYSALQAAVAALVASTQANQPPCLFVPHGKRVVVAAHRLVFVGDTLGRLAASAALRAQVGAAGTMLAQTLRATVLAVKGAALGYPSDTAVQEMARCVAELAGQALRFTTLLDGLLP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7F497-1", "uniprot_id": "F7F497_RAT", "id": "F7F497-1", "name": "", "aln": "MAIATSAQLARALYDNTAESPQELSFRRGDVLRVLQREGAGGLDGWCLCSLHGQQGIVPANRVKLLPASPAPKPSLCPAPPTQPGCSSCPTPERGCEEQEVYVIPPPARPCSASGLPARSCSPSSDSIYKVPRVNGIQLTAPRDVGEVYDVPPNILRAPSNCPYDSPASFSCPATPVVPQPPGEDEAPYDVPLALKSPAEMEPDLEWEGGREPGPPLYAAPSNLKRASALLNLYEAPEELLANGESRDADEGIYDVPLLGPE-PPSPEPPAASSSADPDTVAQLLTRSPPPQHRPRLPSTESLSRRPLPALPVSEAPAPSPAPSPAPGRKGSIQDRPLPPPPPCLPGYGGLKPEGDPECREVDSDSGGPHNEYEGIPMAEEYDYVHLKGVDKAQGSRPLDNAFPADPELLERGLVEQKEALSPEEPLVLSTGDLQLLHFYAGQCQSHYSALQTAVAALMSSTQANQPPCLFVPHGKRVVVAAHRLVFVGDTLGRLAASAPLRAQVGAAGTVLAQTLRATVLAVKGAALGYPSDTAVQEMARCVAELAGQALRFTTLLAGLLP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O43281-1", "uniprot_id": "EFS_HUMAN", "id": "O43281-1", "name": "Embryonal Fyn-associated substrate", "aln": "MAIATSTQLARALYDNTAESPQELSFRRGDVLRVLQREGAGGLDGWCLCSLHGQQGIVPANRVKLLPAGPAPKPSLSPASPAQPG-SPYPAPDHSNEDQEVYVVPPPARPCPTSGPPAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGPYDCPASFSHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAAPSNLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQLLARSPPPPHRPRLPSAESLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQDRPLPPPPPRLPGYGGPKVEGDPEGREMEDDPAGHHNEYEGIPMAEEYDYVHLKGMDKAQGSRPPDQACTGDPELPERGMPAPQEALSPGEPLVVSTGDLQLLYFYAGQCQSHYSALQAAVAALMSSTQANQPPRLFVPHSKRVVVAAHRLVFVGDTLGRLAASAPLRAQVRAAGTALGQALRATVLAVKGAALGYPSSPAIQEMVQCVTELAGQALQFTTLLTSLAP", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******:*************************************************************.*******.**.*:*** *. *:*::. *:*****:*******.:** ** .*.**.* ***:** .* **:*.**. *******. **.**. ***.***** * : *.**** **:*******: *.***:* * ***********:*************************:**. .:************* ******* * :* * **:*** :**.** *******:*************.***:***.********************* ****** * ***** **: .*..* ********************:*.****** *:* . **** ***: :***** ****:********:**************:*****::******** *****.************************.***** **** *.*:*****************..*:***.:**:*******:***** .* *", "identical_positions": 445, "similar_positions": 72, "identity": "79.18%" }, { "cls_id": "homologset.agr.RGD:1308967", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "B0BNK8-1", "uniprot_id": "TET5B_RAT", "id": "B0BNK8-1", "name": "Terminal nucleotidyltransferase 5B", "aln": "--------------------------------------------------------------------------------------------------------------------MMPSESGD-------------ESLEQ-----------------------------------PAAQVGTGAASAVATAG-----------------------------------------------------------AAGGG-----------------------------------PDLEASSASLG------------------------------------RHQSR------------------------------------------------------LSWPQVKRLDALLKEPIPIHGRGNFPTLSVQPQQIVQVVRSSLEEQ------GLHVHSVRLHGSAASHVLHPESGLGYKDLDLVFQMDLQSEASFQLTKAVVLACLLDFLPAGVSRAKITPLTLKEAYVQKLVKVCT--DLDRWSLISLSNKSG-KNVELKFVDSVRRQFEFSIDSFQIILDSLLLFGQCSSTPMSEAFHPTVTGESLYGDFAEALEHLQHRVIATRSPEEIRGGGLLKYCHLLVRGFRPRPSTDVRALQRYMCSRFFIDFPDPVEQRRILERYLEAHFGGA-EAARRYACLVTLHRVVNESTVCLMSHERRQTLDLITMLALQALAE--------------------------------------------------------------------QGP------------AAMAALAWRRPG--SDGVVPATVNYYVTPMQPLLPRAHSYPTWLP-----CN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C152-1", "uniprot_id": "TET5B_MOUSE", "id": "Q8C152-1", "name": "Terminal nucleotidyltransferase 5B", "aln": "--------------------------------------------------------------------------------------------------------------------MMPSESGA-------------ESLEQ-----------------------------------PAAQVGTGAASAVATAG-----------------------------------------------------------AAGGG-----------------------------------PDPEASSASLG------------------------------------RHQSR------------------------------------------------------LSWPQVKRLDALLKEPIPIHGRGNFPTLSVQPQQIVQVVRSSLEEH------GLRVHSVRLHGSAASHVLHPESGLGYKDLDLVFQMDLRSEVSFQLTKAVVLACLLDFLPAGVSRAKITPLTLKEAYVQKLVKVCT--DLDRWSLISLSNKSG-KNVELKFVDSVRRQFEFSIDSFQIILDSLLLFGQCSSTPMSEAFHPTVTGESLYGDFAEALEHLQHRVIATRSPEEIRGGGLLKYCHLLVRGFRPRPSTDVRALQRYMCSRFFIDFPDLVEQRRILERYLEAHFGGA-EAARRYACLVTLHQVVNESTVCLMSHERRQTLDLIAMLALQALAE--------------------------------------------------------------------QGP------------AAMAALAWRRPG--SDGVVPATVNYYVTPMQPLLPRAHSYPTWLP-----CN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96A09-1", "uniprot_id": "TET5B_HUMAN", "id": "Q96A09-1", "name": "Terminal nucleotidyltransferase 5B", "aln": "--------------------------------------------------------------------------------------------------------------------MMPSESGA-------------ERRDR-----------------------------------AAAQVGTAAATAVATAA-----------------------------------------------------------PAGGG-----------------------------------PDPEALSAFPG------------------------------------RHLSG------------------------------------------------------LSWPQVKRLDALLSEPIPIHGRGNFPTLSVQPRQIVQVVRSTLEEQ------GLHVHSVRLHGSAASHVLHPESGLGYKDLDLVFRVDLRSEASFQLTKAVVLACLLDFLPAGVSRAKITPLTLKEAYVQKLVKVCT--DSDRWSLISLSNKSG-KNVELKFVDSVRRQFEFSIDSFQIILDSLLLFGQCSSTPMSEAFHPTVTGESLYGDFTEALEHLRHRVIATRSPEEIRGGGLLKYCHLLVRGFRPRPSTDVRALQRYMCSRFFIDFPDLVEQRRTLERYLEAHFGGA-DAARRYACLVTLHRVVNESTVCLMNHERRQTLDLIAALALQALAE--------------------------------------------------------------------QGP------------AATAALAWRPPG--TDGVVPATVNYYVTPVQPLL--AHAYPTWLP-----CN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A4P7VA97-1", "uniprot_id": "A0A4P7VA97_DROME", "id": "A0A4P7VA97-1", "name": "polynucleotide adenylyltransferase", "aln": "MVNKKADKDKERQQEAMLPAAGKNSSNIENSSKLSNNNNYNNNKTNKGQSTKPNSNNNSGNNKKNAGKGNQQQSQRSGKKAKPQRQQIFLQSLPRDSSNYRSNSFRNSIDINSNSSNMSSKSSSNMSSNSSNISDTLATLDSGVGKINPAELLTAALAVPCAKCSKPSMISGLTTAVTASTVPASASSSSASASSFSSSSTSSGSETASNHSDLHYPEPVVYSAKQYRKSKSYMGVSQYNSSQNGHQAGRAPNTAGGGNGNHVAYRRSHSDRRNSFDRSFAERNRDFVPIVPPPRPVLSSSNIAGVMASTTKLTIIERLGKGRLAYPIMQCGTLDGAEPLYHQQRSNRMDVYQIDDGFHSDGGTETPPPSPSSGSSIASTSDHGSLESVDTGGTQRLAVLSFEQVSKLHDVMDEKVAIHGRGNFPTLEVKLKDLVNLVRRKLEAEVNAGGAGVLVKDIRLNGGAASHVLASEDQP-YNDLDLIFAIELSSPRVFDRVKVAVLNTLLDLMPEGVCKRRIYTCSLKEAYVGKMVKVNNNNDGDRWSLISLGNSPGHKNVELKFVDTMRRQFEFSVDSFQIVLDSLLLFYDCAALPISENFYPTVVGESVYGDFQEALYHLQKKLISTRQPEEIRGGGLLKYCNLLVRNYKAVDSQLIKTLERYMCSRFFIDFPDINTQTTKLEAYLRNHFWGVDEEPLQYQYLMHLREVVEMSTVCLMGHERRQSLHLIQSLAAQVLFNKQEKQQQQQAQEKYQQQQQQQQHQQNQQQQQQQRQHQFLDPAQQQQQQQQTQTQQQQAQQATTLTLVPQAPPTGQAQTIYVQQAAPAAVCCTSSADQTATAAPQTIQIQAGPPGLIYANGVYYAPVIPSTICTCNSTWLSTXLERQEQEKEQQHHQHEQQQFQQQQWSEDALGATLLAETETEPPLATASIAPPPPSSQPPSSPSTTAPRTQVQNQTRSTTINSSNRKKKNKAKTQSKQQTQTATEAESNCNEKPTTATMTRTTTKKSSRIKQMAAAAAATEACAAKGGAGGITGSLVLTPQQINGLPVYNQLDDGGRSAAGTYSGQFAYFYPHDGSAPSMFLLGEDSYLNVTEQQEQHQHQHQHHNHQFV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.*:*. : .*: * :.*::: *:*. .**** * *: . * . **: **.:*. ::.* :.**********.*: :::*::** .** . *: *:.:**:*.****** .*. *:****:* ::* * *: .*..** ***::* **.: :* . :****** *:*** . * ********.*..* *********::*******:*****:******* :*:: *:** *:***.***:**** *** **::::*:**.*************:****.::. * :::*:************* * ** **. ** *. : . :* *: *:.**: ******.*****:*.** ** *.* : *.* ** **:. .. : ..* *:: . * : . *.. :* ** ", "identical_positions": 216, "similar_positions": 119, "identity": "19.49%" }, { "cls_id": "homologset.agr.RGD:1308968", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9BWG6-1", "uniprot_id": "SCNM1_HUMAN", "id": "Q9BWG6-1", "name": "Sodium channel modifier 1", "aln": "-MSFKREGDDWSQLN------VLKKRRVGDLLASYIPEDEALMLRDG----RFACAICPHRPVL--DTLAMLTAHRAGKKHLSSLQLFYGKKQ-----------PGKERKQNPKHQNELRRE----ETKAEAPLLTQTRLITQSALHRAPHYNSCCRRK-----YRPEAPGPSVSLSPMPP-----------SEVKLQS------GKISREP-----EPAAGPQAEESATVSAPAPMSPTRRRALDHYLTLR-------------SSGWIPDGRGRWVKDENVEFDSDEE-----EPPDLPLD------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8K136-1", "uniprot_id": "SCNM1_MOUSE", "id": "Q8K136-1", "name": "Sodium channel modifier 1", "aln": "-MSFKREGDDWSQLN------VLKKRRVGDLLASYIPEDEALMLRDG----RFACAICPHRPVL--DTLAMLTAHRAGKKHLSSLKLFYGKKQ-----------TGKGTEQNPRQQNELKT-----ESKTEAPLLTQTRIITQNALHRAPHYNSCCRRK-----HRPEAPAPSVSSPPLPT-----------AEVQLQS------AEISKEP-----EPRERSDAKESAALLASAPMSPTKRRVLNHYLTLR-------------SSGWVPDGRGRWIKDENVEFDSDEE-----EPPDLPLD------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q2YDS5-1", "uniprot_id": "SCNM1_DANRE", "id": "Q2YDS5-1", "name": "Sodium channel modifier 1", "aln": "-MSFKREGDDQSQLN------ILKKRRVSDLLSNFIPDDEATLMKNG----RYSCLVCSHRPVF--DTVDMLVVHRKGKRHLEGMKWFYGKKN-----------QLRREIDKRRHQDYVKAEDDRQEPSSSAPLLTQTRKITHHALLRTVPYSSCHKKA-----SERSESSSKEHRNDLAN-----------SHLSMRTESNDSRTTVHQGPSEVKGEAKKKKKGASTLSSSVCEPLTEQRRRELDHYLKLK-------------SSGWLQDRSGKWVKDENVEFDSDEE-----EPTLLPPCSESS--------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D3ZSG3-1", "uniprot_id": "D3ZSG3_RAT", "id": "D3ZSG3-1", "name": "", "aln": "MSSYQKELEKYRDIDEDEILRTLSPEELEQLDCELQEMDPENMLLPAGLRQRDQTKKSPTGPLDRDALLQYLEQQALEVKERDDLVPFTGEKKGKPFIQPKREIPAQEQITLEPELEEALSHATDAEMCDIAAILGMYTLMSNKQYYDAICSGEICNTEGISSVVQPDKYKPVPDEPPNPTNIEEMLKRVRSNDKELEEVNLNNIQDIPIPVLSDLCEAMKTNTYVRSFSLVATKSGDPIANAVADMLRENRSLLSLNIESNFISSTGLMAVLKAVRENATLTELRVDNQRQWPGDAVEMEMATVLEQCPSIVRFGYHFTQQGPRARAANAMTRNNELRRQQKKR", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:::* :. ::: *. ..: :* .. * :: . * .. *: : * : :. ..: * *:*: : . : * *.:* ::: : .. . . . . . . .:. : *. : : . . . : : *:* : . : .*: *:: :. : ", "identical_positions": 19, "similar_positions": 70, "identity": "5.51%" }, { "cls_id": "homologset.agr.RGD:1308970", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q641Y0-1", "uniprot_id": "OST48_RAT", "id": "Q641Y0-1", "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit", "aln": "---------------MKMVPRLAVRAWPLCGLLLAALGCVCASGPRTLVLLDN-LNVRDTHSLFFRSLKDRGFELTFKTADDPSLSLIKYG--EFLYDNLIIFSP-SVEDFGGNINVETISAFIDGGGSVLVAASS-DIGDPLRELGSECGIEFDEEKTAVIDHHNYDVSDLGQHTLIVADTENLLKAPTIVGKSS----LNPILFRGVGMVADPDNPLVLDILTGSSTSYSFFPDKPITQYPHAVGRNTLLIAGLQARNNARVIFSGSLDFFSDAFFNSAVQKAAPGAQRYSQTGNYELAVALSRWVFKEEGVLRVGPVSHHRVGETAPPN-AYTVTDLVEYSIVIEQLSNGKWVPFDGDDIQLEFVRIDPFVRTFLKRK------GGKYSVQFKLPDVYGVFQFKVDYNRLGYTHLYSSTQVSVRPLQHTQYER--FIPSAYPYYASAFSMMAGLFLFSVVFLHMK---------EKEKSD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54734-1", "uniprot_id": "OST48_MOUSE", "id": "O54734-1", "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit", "aln": "---------------MKMDPRLAVRAWPLCGLLLAVLGCVCASGPRTLVLLDN-LNVRDTHSLFFRSLKDRGFELTFKTADDPSLSLIKYG--EFLYDNLIIFSP-SVEDFGGNINVETISAFIDGGGSVLVAASS-DIGDPLRELGSECGIEFDEEKTAVIDHHNYDVSDLGQHTLIVADTENLLKAPTIVGKSS----LNPILFRGVGMVADPDNPLVLDILTGSSTSYSFFPDKPITQYPHAVGRNTLLIAGLQARNNARVIFSGSLDFFSDAFFNSAVQKATPGAQRYSQTGNYELAVALSRWVFKEEGVLRVGPVSHHRVGEMAPPN-AYTVTDLVEYSIIIEQLSNGKWVPFDGDDIQLEFVRIDPFVRTFLKRK------GGKYSVQFKLPDVYGVFQFKVDYNRLGYTHLYSSTQVSVRPLQHTQYER--FIPSAYPYYASAFSMMAGLFIFSIVFLHMK---------EKEKSD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P39656-1", "uniprot_id": "OST48_HUMAN", "id": "P39656-1", "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit", "aln": "MGYFRCARAGSFGRRRKMEPSTAARAWALFWLLLPLLGAVCASGPRTLVLLDN-LNVRETHSLFFRSLKDRGFELTFKTADDPSLSLIKYG--EFLYDNLIIFSP-SVEDFGGNINVETISAFIDGGGSVLVAASS-DIGDPLRELGSECGIEFDEEKTAVIDHHNYDISDLGQHTLIVADTENLLKAPTIVGKSS----LNPILFRGVGMVADPDNPLVLDILTGSSTSYSFFPDKPITQYPHAVGKNTLLIAGLQARNNARVIFSGSLDFFSDSFFNSAVQKAAPGSQRYSQTGNYELAVALSRWVFKEEGVLRVGPVSHHRVGETAPPN-AYTVTDLVEYSIVIQQLSNGKWVPFDGDDIQLEFVRIDPFVRTFLKKK------GGKYSVQFKLPDVYGVFQFKVDYNRLGYTHLYSSTQVSVRPLQHTQYER--FIPSAYPYYASAFSMMLGLFIFSIVFLHMK---------EKEKSD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NYS8-1", "uniprot_id": "OST48_DANRE", "id": "Q6NYS8-1", "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit", "aln": "---------------MATALSGGFSKNALFILSAALMLQAVLGDGKTLVLLDN-PNIRDTHSIFFRSLADRGFDLTFKTADDPGLSLIKYG--QFLYDHLILFSP-SVEDFGGNINVETITAFIDGGGNVLVAASS-DIGDPLRELGSECGIEFDEEKTAVIDHHNYDISDPGEHTLIVADPENLLKAPTIVGKPT----DKPVLFKGVGMVADPDNPLVLDILTGSSTSYSYFPDRPITQYPHAVGKNTLLIAGLQARNNARVVFSGSLHFFSDAFFNSAVQKAATGSKRYEQTGNQDLAEALSRWVFKEAGVLRVGDVTHHPVGESTPPA-AYTVTDLVEYGIVIEMLSGGKWVPFDGDDIQLEFVRIDPFVRTYLKKN------GGKYSVQFKLPDVYGVFQFKVDYNRLGYTHLYSSTQVSVRPLQHTQYER--FIPSAFPYYASAFSMMAGLFVFSVVFLHMR---------EKEKSD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24319-1", "uniprot_id": "OST48_DROME", "id": "Q24319-1", "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit", "aln": "---------------------MMWKALLIAVLAIAHCQAVLETDANTLVLLDN-LAIRETHSIFFKSLQDRGFKLTYKLADDSSLLLSKYG--EYLYKNVIIFAP-SVEEFGGDVSVERLAQFVDDGGNVLVAGSE-KSGDALREFASECGFELDEENAAVIDHLHYDVSDAGEHTTILTSAKNLIQADTIVGKANRQADAAPLLYRGTGLIADKENPLVLKLLTAESTAYSYNPEASVSDYPHAVGRGTLLIAALQARNNARVVFSGSLLFFSDESFTTAVQYAQSG-VFHKLAGNRDVAESISKWVFGETGRLRVASVQHHKEGELLPPDQAYTITDPVVYTIGIEELVQGEWRAFKASDIQLEFVRIDPFVRTYLKQTN-----TGAYQAKFKIPDVYGVYQFKVDYNRVGYTHLYSTTQVSVRPLEHTQYER--FIPSAFPYYTSAFSMMIGVFVFSFVFLHFKDEPVGRAAKEDKKSQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P33767-1", "uniprot_id": "OSTB_YEAST", "id": "P33767-1", "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit WBP1", "aln": "---------------------MRTDWNFFFCILLQAIFVVGTQTSRTLVLYDQSTEPLEEYSVYLKDLEQRNYKLEYLDINSTSTTVDLYDKEQRLFDNIIVFPTKGGKNLARQIPVKQLIKFFENEGNILCMSSPGAVPNTIRLFLNELGIYPSPKGHVIRDYFSPSSEE------LVVSSNHLLNKYVYNARKS-----EDFVFGESSAALLENREQIVPILNAPRTSFTESKGK---CNSWTSGSQGFLVVGFQNLNNARLVWIGSSDFLKNK----------------NQDSNQEFAKELLKWTFNEKSVIKSVHAVHSHADGTSYDEEPYKIKDKVIYSVGFSEWNGEEWLPHIADDIQFELRQVDPYYRLTLSPSGNDSETQYYTTGEFILPDRHGVFTFLTDYRKIGLSFTTDKDVKAIRHLANDEYPRSWEISNSWVYISAICGVIVAWIFFVVSFVTTSSVG--KKLETFKKTN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . .**** *: : :*::::.* :*.:.* : :... : *. : *:.::*:*.. . :::. :: *: : *.:. *.:* .* :.:* : .* *: . : .: *: . .: ::...::*:: . .: . .:: . :. :: :*.. *::: . : * :*:..:* ****::: ** *:.: . .* :.* : :*.* * . :: . * . .*.:.* * * : :. :* .. ..***:*: ::**: * *. . :* :** :**: * .**.::* :. .. ::* * : :* * *..:: * :: .:: . :.* . *: :*::", "identical_positions": 72, "similar_positions": 164, "identity": "14.91%" }, { "cls_id": "homologset.agr.RGD:1308971", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ERM2-1", "uniprot_id": "ICAM4_MOUSE", "id": "Q9ERM2-1", "name": "Intercellular adhesion molecule 4", "aln": "MESALLL-PSLLLVAAYPRGGSPQ---QEWMQSPP----APSVTSAPFWVRLNPELEAVPPGGSAWLNCSHNCPLPVHSSLRTQLRQGKIVNGSGWVSYQLLDVRAWNSKVRCVVTCAGETREATARITAYKRPRSVILEPPVLVGHKYTLRCYVTHVFPVGFLVVSLRRGGRVIYHESLERFTGSDLANVTLTYVMRAGLNDLWQPLTCHARLNLDGLVVRSSSAPVMLTVLALSPASIALASTSIATLVGILLAVGAVYVRKYLAVQT--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZP29-1", "uniprot_id": "D3ZP29_RAT", "id": "D3ZP29-1", "name": "Intercellular adhesion molecule 4", "aln": "MESALLL-LSLLLVAAYLRGGSSQ---HEWMQSPP----APSVTSVPFLVRLSPELEAVPPGGSVWLNCSHNCPLPVHSSLRTQLRQGKIVNGSGWVSYQLLDVRAWNSKVRCVVTCAGETREATARITAFKRPRSVILEPPVLVGHKYTLRCYVTHVFPVGFLVVSLRKGGRVVYHESLQRFTGSDLANVTLTYVMRAGLNDLWQPLTCHARLNLDGLVVRSSSAPVMLTVLALSPASISLASISIATLVGIFLAVGAVYVRKYLAVQTQL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14773-1", "uniprot_id": "ICAM4_HUMAN", "id": "Q14773-1", "name": "Intercellular adhesion molecule 4", "aln": "MGSLFPLSLLFFLAAAYPGVGSALGRRTKRAQSPKGSPLAPSGTSVPFWVRMSPEFVAVQPGKSVQLNCSNSCPQPQNSSLRTPLRQGKTLRGPGWVSYQLLDVRAWSSLAHCLVTCAGKTRWATSRITAYKPPHSVILEPPVLKGRKYTLRCHVTQVFPVGYLVVTLRHGSRVIYSESLERFTGLDLANVTLTYEFAAGPRDFWQPVICHARLNLDGLVVRNSSAPITL-MLAWSPAPTALASGSIAALVGILLTVGAAYLCKCLAMKSQA", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * : * ::*.*** **. : *** *** **.** **:.**: ** ** *. ****:.** * :***** ***** :.*.*************.* .:*:*****:** **:****:* *:********* *:******:**:*****:***:**:*.**:* ***:**** ********* : ** .*:***: *************.****: * :** ***. :*** ***:****:*:***.*: * **::: ", "identical_positions": 171, "similar_positions": 51, "identity": "62.87%" }, { "cls_id": "homologset.agr.RGD:1308972", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "G3V6D1-1", "uniprot_id": "G3V6D1_RAT", "id": "G3V6D1-1", "name": "", "aln": "MAAPRGPGLFFKPALLGLLGVAWCSLGFGVSRDDDLLLPYPLAR-----RRPSRDCARVHAGSPEQESWPPPPTNPGASHRAAVRTFVSHFEG-----RAVAGHLTRVADPLRTFSVLEPGGPGGCAQRRRATVEDTAVPAGCRVAQNGGFFRMGTGECLGNVVSDGRLVSSSGGLQNAQFGIRRDGTLVTGYLSEEDVLDTVNPFVQLLSGVVWLIRNGSIYINESQITECDETQETGSFSKFVNVMSARTAVGHDRKGQLILFHADGQTEQRGLNLWEMAEFLLKQDVVNAINLDGGGSATFVLNGTLASYPSDHCQDNMWRCPRRVSTVVCVHEPRCQPPNCSGHGTCVDGRCECTSHFWHGEACSELNCGPSNCSQHGLCTETGCRCDAGWT-------------------------------------------GSNCSEECPLGWYGPGCQRPCQCEHQRPCDPQTGNC----------SISQVKQCLQS------TEAPPRAGGLASFTGTTWLALTLILIFLLLISTAVNVSLLLGSRAERNRHLDGDYVYHPLQEVNGDA----LAAEKEQTEETCNPFKD--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BJ48-1", "uniprot_id": "NAGPA_MOUSE", "id": "Q8BJ48-1", "name": "N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase", "aln": "MAAPRGPGLFLIPALLGLLGVAWCSLSFGVSRDDDLLLPYPLAR-----RRPSRDCARVRSGSPEQESWPPPPTNPGASHHAAVRTFVSHFEG-----RAVAGHLTRVADPLRTFSVLEPGGAGGCAQKRRATVEDTAVPAGCRIAQNGGFFRMSTGECLGNVVSDGRLVSSSGGLQNAQFGIRRDGTIVTGYLSEEEVLDPVNPFVQLLSGVVWLIRNGNIYINESQAIECDETQETGSFSKFVNVMSARTAVGHDREGQLILFHADGQTEQRGLNLWEMAEFLRQQDVVNAINLDGGGSATFVLNGTLASYPSDHCQDNMWRCPRQVSTVVCVHEPRCQPPDCSGHGTCVDGHCECTSHFWRGEACSELDCGPSNCSQHGLCTETGCHCDAGWT-------------------------------------------GSNCSEECPLGWYGPGCQRPCQCEHQCSCDPQTGNC----------SISQVRQCLQP------TEATPRAGELASFTRTTWLALTLTLIFLLLISTGVNVSLFLGSRAERNRHLDGDYVYHPLQEVNGEA----LTAEKEHMEETSNPFKD--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UK23-1", "uniprot_id": "NAGPA_HUMAN", "id": "Q9UK23-1", "name": "N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase", "aln": "MATSTGRWLLLRLALFGFLWEASGGLDSGASRDDDLLLPYPRAR-----ARLPRDCTRVRAGNREHESWPPPPATPGAGG-LAVRTFVSHFRD-----RAVAGHLTRAVEPLRTFSVLEPGGPGGCAARRRATVEETARAADCRVAQNGGFFRMNSGECLGNVVSDERRVSSSGGLQNAQFGIRRDGTLVTGYLSEEEVLDTENPFVQLLSGVVWLIRNGSIYINESQATECDETQETGSFSKFVNVISARTAIGHDRKGQLVLFHADGQTEQRGINLWEMAEFLLKQDVVNAINLDGGGSATFVLNGTLASYPSDHCQDNMWRCPRQVSTVVCVHEPRCQPPDCHGHGTCVDGHCQCTGHFWRGPGCDELDCGPSNCSQHGLCTETGCRCDAGWT-------------------------------------------GSNCSEECPLGWHGPGCQRPCKCEHHCPCDPKTGNC----------SVSRVKQCLQP------PEATLRAGELSFFTRTAWLALTLALAFLLLISTAANLSLLL-SRAERNRRLHGDYAYHPLQEMNGEP----LAAEKEQPGGAHNPFKD--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NEE2-1", "uniprot_id": "A0A8M1NEE2_DANRE", "id": "A0A8M1NEE2-1", "name": "", "aln": "MAKCFVYFDLFFLFLACLGVCLCQCKDIRHSSDDDLLLPYTKSHGPSHSHRYVRDCQPVAHGTVTHETQAASKHSN--SPVLESNIFISDITDDSGTHRWVSGHITEVHDPLRSVSVLEPGGPGGCAHNHRELVEVTAKTRKCLVAQNGGYFDTHTGQCLGNIISDGKLVRNSGGIQNAQFGIRKDGTLVFGYLSEDDILDQENPFVQLISGVVWLLRKGEIYINESIQAECDKTQETGNFRHFVDVISARTAVGHDKEGKLILFHVDGQTDVRGMNLWQVAKFLKDQNVMNAINLDGGGSATYVLNGSLASYPSDHCNPSKWRCPRAISTVLCIHERLCQPEDCSGHGRCVEGQCVCQ-HGWSTPGCANLTC-QAECGEHGICTENGCVCDAGWMGLYCSQVCTAGLYGDGCNQTCTCANGGSCDPVHGRCTCPAGFHGDSCEQECPIGFYGLNCKQLCQCQDMCPCDAATGSCNTTYQGERNISLHRAGHCLATQMWREWRQEEEAQAPRPYLSEQSWLVVCSILATSLLASLTG--NLIQTCRKCKARRQRADYSYLPLGEINGATERGEMKSGKVLFQQGDSDSQDSS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** :: * : . * ********. :: * *** * *. :*: ... . . . *:*.: . * *:**:*.. :***:.*******.**** .:* ** ** . * :*****:* :*:****::** : * .***:********:***:* *****:::** ******:******:*:*.****** ***:*****.* :**:*:*****:***::*:*:***.****: **:***::*:** .*:*:************:****:*********: . ***** :***:*:** *** :* *** **:*:* * * * .* :* * ::*.:**:***.** ***** *..*.:***:*::* .*:: *:*:. .**. **.* *: :. :** . : . . :: :**.: * ** * .*: .* : *: .** * ** *:** . : : * . :* ", "identical_positions": 244, "similar_positions": 127, "identity": "41.22%" }, { "cls_id": "homologset.agr.RGD:1308973", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q56A27-1", "uniprot_id": "NCBP1_RAT", "id": "Q56A27-1", "name": "Nuclear cap-binding protein subunit 1", "aln": "--MSRRRHSYENDGGQPHKR---RKTSDANETEDHLESLICKVGEK--SACSLESNLEGLAGVLEADLP---NYKSKILRLLCTVARLLPEKLTIYTTLVGLLNARNYNFGGEFVEAMIRQLKESLKANN-------------YNEAVYLVRFLSDLVNCHVIAAPS--MVAMFENFVSVTQEEDVPQVRRDWYVYA-FLSSLPWVGKELYEKKDAEMDRIFSSTESYLKR---RQKTHVPMLQVWTADKPHPQEEYLDCLWAQIQKLKKDRWQER--------HILRPYLA---FDSILCEALQHNLPPFTPPPH---TEDSVYPMPRVIFRMFDYTDDPEGPVMPGSHSVERFVIEENLHCIIKSYWKERKTCAAQLVSY--------------------------PGKNKIPLNYHIVEVIFAELFQLPAPPHIDVMYTTLLIELCKLQPGSLPQVLAQATEMLYMRLDTMSTTCVDRFINWFSHHLSNFQFRWSWEDWSDCLTQDLE---SPKPKFVREVLEKCMRLS-YHQHILDIVPPTFSALCPANPTCIYKYGDESSNSLPGHSVALCLS---------------------VAFKSKATNDEIFSILKDVPNPNQVDDDDEGFRFNPLKIEVFVQTLLHLAAKSFSHSFSALAKFHEVFKTLAE-----SDKGKLHVLRVMFEVWRNHPQMIAVLVDKMIRTQIVDCAAVANWIFSSELSRDFTRLFVWEILHSTIRKMNKHVLKIQKELEEAKEKLARQHKRRSDDDDRGSDRK-------DGALEEQIERLQEKVESAQSEQKNLFLVIFQRFIMILTEHLVRCETDGTSILTPWYKNCIERLQQIFLQHHQIIQQYMVTLENLLFTAELDPHILAVFQQFCALQA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UYV9-1", "uniprot_id": "NCBP1_MOUSE", "id": "Q3UYV9-1", "name": "Nuclear cap-binding protein subunit 1", "aln": "--MSRRRHSYENDGGQPHKR---RKTSDANETEDHLESLICKVGEK--SACSLESNLEGLAGVLEADLP---NYKSKILRLLCTVARLLPEKLTIYTTLVGLLNARNYNFGGEFVEAMIRQLKESLKANN-------------YNEAVYLVRFLSDLVNCHVIAAPS--MVAMFENFVSVTQEEDVPQVRRDWYVYA-FLSSLPWVGKELYEKKDAEMDRIFSTTESYLKR---RQKTHVPMLQVWTADKPHPQEEYLDCLWAQIQKLKKDRWQER--------HILRPYLA---FDSILCEALQHNLPPFTPPPH---TEDSVYPMPRVIFRMFDYTDDPEGPVMPGSHSVERFVIEENLHCIIKSYWKERKTCAAQLVSY--------------------------PGKNKIPLNYHIVEVIFAELFQLPAPPHIDVMYTTLLIELCKLQPGSLPQVLAQATEMLYMRLDTMSTTCVDRFINWFSHHLSNFQFRWSWEDWSDCLTQDLE---SPKPKFVREVLEKCMRLS-YHQHILDIVPPTFSALCPANPTCIYKYGDESSNSLPGHSVALCLS---------------------VAFKSKATNDEIFSILKDVPNPNQVDDDDEGFRFNPLKIEVFVQTLLHLAAKSFSHSFSALAKFHEVFKTLAE-----SDKGKLHVLRVMFEVWRNHPQMIAVLVDKMIRTQIVDCAAVANWIFSSELSRDFTRLFVWEILHSTIRKMNKHVLKIQKELEEAKEKLARQHKRRSDDDDRSSDRK-------DGALEEQIERLQEKVEAAQSEQKNLFLVIFQRFIMILTEHLVRCETDGTSILTPWYKNCIERLQQIFLQHHQTIQQYMVTLENLLFTAELDPHILAVFQQFCALQA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q09161-1", "uniprot_id": "NCBP1_HUMAN", "id": "Q09161-1", "name": "Nuclear cap-binding protein subunit 1", "aln": "--MSRRRHSDENDGGQPHKR---RKTSDANETEDHLESLICKVGEK--SACSLESNLEGLAGVLEADLP---NYKSKILRLLCTVARLLPEKLTIYTTLVGLLNARNYNFGGEFVEAMIRQLKESLKANN-------------YNEAVYLVRFLSDLVNCHVIAAPS--MVAMFENFVSVTQEEDVPQVRRDWYVYA-FLSSLPWVGKELYEKKDAEMDRIFANTESYLKR---RQKTHVPMLQVWTADKPHPQEEYLDCLWAQIQKLKKDRWQER--------HILRPYLA---FDSILCEALQHNLPPFTPPPH---TEDSVYPMPRVIFRMFDYTDDPEGPVMPGSHSVERFVIEENLHCIIKSHWKERKTCAAQLVSY--------------------------PGKNKIPLNYHIVEVIFAELFQLPAPPHIDVMYTTLLIELCKLQPGSLPQVLAQATEMLYMRLDTMNTTCVDRFINWFSHHLSNFQFRWSWEDWSDCLSQDPE---SPKPKFVREVLEKCMRLS-YHQRILDIVPPTFSALCPANPTCIYKYGDESSNSLPGHSVALCLA---------------------VAFKSKATNDEIFSILKDVPNPNQDDDDDEGFSFNPLKIEVFVQTLLHLAAKSFSHSFSALAKFHEVFKTLAE-----SDEGKLHVLRVMFEVWRNHPQMIAVLVDKMIRTQIVDCAAVANWIFSSELSRDFTRLFVWEILHSTIRKMNKHVLKIQKELEEAKEKLARQHKRRSDDDDRSSDRK-------DGVLEEQIERLQEKVESAQSEQKNLFLVIFQRFIMILTEHLVRCETDGTSVLTPWYKNCIERLQQIFLQHHQIIQQYMVTLENLLFTAELDPHILAVFQQFCALQA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7K4N3-1", "uniprot_id": "NCBP1_DROME", "id": "Q7K4N3-1", "name": "Nuclear cap-binding protein subunit 1", "aln": "--MSRRRAHDTEDEGYDHRRNKRRRVSENQEIEDRLESLILRVGER--STSSVESNLEGLVSVLEADLG---TFRLKILRILSDCAVRMPEKCTVYTTLVGLLNAKNYKFGGEFVDHMVKTFKESLKMCR-------------WDAARYSLRFLADLVNCHVISATS--LLQLLDTMIDVSNEDTVPQVRRDWFVFA-VLSTLPWVGRDLYEKKESALESLLLRIEVYLNK---RSKKHHNALRVWSSDAPHPQEEYLDCLWAQIRKLRQDNWAEK--------HIPRPYLV---FDSILCEALQHNLPTIVPPPH---HDNFEYPMPWVVYRMFDYTDCPDGPNLPGAHSIERFLIEEHLHHIIETYHHERKDCAAQLLSF--------------------------PYKHKIPLEYCIVEVVFAELFHMPTPRYLDICYGSILIELCKLQPATLPQVLAQATEILFMRIDSMNTSCFDRFVNWFSYHLSNFKFTWSWDEWDSCLLLDGE---HPRPKFIQEVLQKCLRLS-YHQRITEMMPTTYAKLIPLTPVPNYKYANEEAANLPGTTVAHQLV---------------------VAIRQKCTPEEVVNILKDIPNSGYSGEEMSDGSFNALKIDVFVQTLLNLGSKSFSHSFAAISKFHSVFRALAE-----TEEAQICILHNIFELWSSHQQMMVVLIDKLLKLQIVDCSAVATWIFSKEMTGEFTKLYLWEILHLTIKKMNKHVIKLNTELSEAKEKLAKADSSSSDSEDDSSHKRKKPITHADKPSEEVVERMEEKLEAANVNQKRLFLIVFQRFIMILSEHLLRSDTDGRDPDTDWYRWTIGRLQQVFLMHHEQVQKYSSTLETLLFTSDLDTHILEVFQQFVALRA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P34160-1", "uniprot_id": "NCBP1_YEAST", "id": "P34160-1", "name": "Nuclear cap-binding protein complex subunit 1", "aln": "MFNRKRRGDFDEDENYRDFRPRMPKRQRIPPVVQLCKEMMPDIRTIGESVKAFEDDIKFLSEAIMNEYGHEDYFNNALLSTLNAVVVEQPQKQAAIALLTMVVNSKNNVAGKSIINYFFEELQKWCKQTYNDEFKSTSNETGPWNKIKLILRFLSILSPMFLVDELINIYKSLFELSIELNNLDPGNRVPLSEAIYTNTLLNIPYL--FFFNRNNDGLRTKVEELLAYVEQNYLVKTTDINLLREYNGEPPYEMVELVRVVLPNVKKALINNLEQLNELFPDWNHLLTPQTGDEGFNDALTLPSVDDLKSFVRLNKNFGSVDSMWKTPRYAFHVYLPNSAGNFETVVPISTYAGQLFNDIIIDLVESLEFNRKEVARQVITLDLFFKAGIFTEPGESIAQLIATYEENPLAPTFKIEDLAIETILGLIFKLPSVSQPFAYFYTLLVDICQNSPKAIAPVFGRAFRFFYSHLDSLDFELKLRYLDWFSIQMSNFNFSWKWNEWEDDSIKFGKYFYNPKVNFAKNLIQKELRLTSNFSEVEDSLPQEFTKYLDTSYIPRDQLINYYQSLFTGYTVEEDSVRKNDLYFRQEGVPMENTVRKILDYTHKANNSREVTELESILGELKNEYGSIISDFNRFVIILLVQAVTDSGSRSLSHANKYINDLKEDLKTIFAKIELDIETKEYIIIEAVLTFWNANPQTGFLVADAFKYAGLLTSRTIFTFIFN-ETGLKNNGLIEATAIEAVFRNLSQQISEENESGNNFEFVFERLCTIANSTIDLLDVNA---------DEDIEIPKVNGEMDIDDIEDDKLDLKWKYFTVIGFIKSILRRYS---------------------HEYRELADKFIANIDNAIPHESTRRTISNWIQETKEV--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :** :* . . * : . : :.:: : *. :.*.::: * .: : :. :* * . *:* : : *. ::*::* * .::: :.. ::: * :: :***: * .:: ::: :.:.: : :* . ::: * .:*:: :::::: : . *::: .... *: :..: *: * : : .:::* :. : *: * *:. * . .:* .:. : : : * :::: .. : : : :::: : :::: :** * *::: * .: :: :*.::. :*::*: : ::*:::*: .* ::. *:.:* .::: ::*::. *:::*** ::***:* *.*::*.. : *: :* :::::* :**: ...: : :* :: . : : :.* :* : *.. .. .. *:.: . ** : * ::**:: . .::*:**: : .::. :::: : : ::. :: .* : * :: * : :: . :: .:**. * . . * :. .::::.::: : : . .: : : : . .. * . . : : ::: ::: : ::..* * :: : : ::* : ::: ::: .::. : . * :*: : ", "identical_positions": 90, "similar_positions": 316, "identity": "10.04%" }, { "cls_id": "homologset.agr.RGD:1308974", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q61846-1", "uniprot_id": "MELK_MOUSE", "id": "Q61846-1", "name": "Maternal embryonic leucine zipper kinase", "aln": "--MKDYDELLKYYELYETIGTGGFAKVKLACHVLTGEMVAIKIMDKNALGSDLPRVKTEIDALKSLRHQHICQLYHVLETKNKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQILSAVAYVHSQGYAHRDLKPENLLFDENHKLKLIDFGLCAKPKGNKDYHLQTCCGSLAYAAPELIQGKSYLGSEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYEVPKWLSPSSILLLQQMLQVDPKKRISMRNLLNHPWVMQDYSCPVEWQSKTPLTHLDEDCVTELSVHHRSSRQTMEDLISSWQYDHLTATYLLLLAKKARGKPARLQLLSFSCGTASTTPKS---------------------------KNLSLEDMSTSDDNCVAG--LIDYELCEDKLLA----PKTPQVT------------KHLAESNHAASKSPAPGVRRAVANKLMDKENVCTPKSSVKNEEQFVFSEPKIPVS--KNQYKREIPASP----TRFPTPAKARAQCLREAPVRTPG---NSAGADTLTTGVISPERRCRSMDVDLNQAHMEDTPKKKGTNVFGSLERGLDKVLTALTRNKKKGSARDGPRKRKLHYNVTTTRLVNPDQLLSEIMAILPKKNVDFVQKGYTLKCQTQSDFGKVTMQFELEVCQLQRPDVVGIRRQRLKGDAWVYKRLVEDILSGCKM---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A6T6-1", "uniprot_id": "D4A6T6_RAT", "id": "D4A6T6-1", "name": "Maternal embryonic leucine zipper kinase", "aln": "--MKDYDELLKYYELYETIGTGGFAKVKLACHILTGEMVAIKIMDKNALGSDLPRVKTEIDALKNLRHQHICQLYHVLETKNKIFMVLEYCPGGELFDYIISQDRLSEEETRVIFRQILSAVAYVHSQGYAHRDLKPENLLFDENHKLKLIDFGLCAKPKGNKDYHLQTCCGSLAYAAPELIQGKSYLGSEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYEVPKWLSPSSILLLQQMLQVDPKRRISMKNLLNHPWILQDYSCPIEWQSKASLTHLDEDCITELSVHHRNSRQTMEDLISSWQYDHLTATYLLLLAKKARGKPARLQLLSFSGGTTSTTPKASCRRPVCDLLISPAALFRSRPSKPVQSKNLSLEDMSTSGDSCVAG--LIDYELCEDNLLA----PQTPQFT------------KHWAESNHVECESPTPVVCRALANKLKDKENVCTPKSSVKNQEQFVFSEPKIPVS--RNQYKREILTSP----TQFTAPAKARTQCLRETQVRTPV---NSAGADTLTTNVISPERRCRSMEVDLNQAHMEDTPKRKGTNVFGSLERGLDKVLTALTRNKKKGSAKDGPRRRKLHYNVTTTRLVNPDQLLNEIMAILPKKNVDFVQKGYTLKCQTQSDFGKVTMQFELEVCQLQRPDVVGIRRQRLKGDAWVYKRLVEDILSGCKM---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14680-1", "uniprot_id": "MELK_HUMAN", "id": "Q14680-1", "name": "Maternal embryonic leucine zipper kinase", "aln": "--MKDYDELLKYYELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLGSDLPRIKTEIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCAKPKGNKDYHLQTCCGSLAYAAPELIQGKSYLGSEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYDVPKWLSPSSILLLQQMLQVDPKKRISMKNLLNHPWIMQDYNYPVEWQSKNPFIHLDDDCVTELSVHHRNNRQTMEDLISLWQYDHLTATYLLLLAKKARGKPVRLRLSSFSCGQASATPFTDIK-----------------------SNNWSLEDVTASDKNYVAG--LIDYDWCEDDLSTGAATPRTSQFT------------KYWTESNGVESKSLTPALCRTPANKLKNKENVYTPKSAVKNEEYFMFPEPKTPVN--KNQHKREILTTP----NRYTTPSKARNQCLKETPIKIPV---NSTGTDKLMTGVISPERRCRSVELDLNQAHMEETPKRKGAKVFGSLERGLDKVITVLTRSKRKGSARDGPRRLKLHYNVTTTRLVNPDQLLNEIMSILPKKHVDFVQKGYTLKCQTQSDFGKVTMQFELEVCQLQKPDVVGIRRQRLKGDAWVYKRLVEDILSSCKV---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QGZ6-1", "uniprot_id": "MELK_DANRE", "id": "F1QGZ6-1", "name": "Maternal embryonic leucine zipper kinase", "aln": "MPVDSTSELLKHYEVYETIGSGGFAKVKLGRHKLTGEKVAIKIMEKKDLGDDLPRVKIEIEAMKNLSHQHVCRLYHVIETTSKIYMVLEYCPGGELFDYIIAKDRLSEEETRVFFRQIISALAYVHSQGYAHRDLKPENLLIDEDHNLKLIDFGLCAKPKGGLGFELLTCCGSPAYAAPELIQGKAYIGSEADVWSMGVLLYALLCGFLPFDDDNCMVLYRKITRGKYSNPHWLSPSSILLLNQMMQVDPKRRLTVKHLLDHPWVMRGYSTPVEWHSKYPLGHIDEDCITEMAVTFKQSKQRTIQLVSEWKYDQITATYLLLLAKKRQGRPVRLRAECPVIDIVCSPLQDMQLK-----------------------KSLRFTEDDDGVHPVVLGSMVFPPDCYDDENPWTPLTPKNTHTTNTPRMKLYPETTEKWNEMAYSPVIEHSRPCRQKPERRERTKENKENLAVPGTDGDVFALPAPRTPTSSRKVKSNRTVMTTPNHNNNKSSEVNKGAGSATKEGSRRREVEQQQNGQQGELNILAFSPERRSRS--LDLAGCQVDSGQKRKGGKVFGSLERGLDKVITMLTPSKKRG-PRDGPRKIKAQYNVTLTNQTNADQVLNQILSILPEKNVDFVQKGYTLKCHTQSDFGKVTMQFELEVCLLQKPEVVGIRRQRLKGDAWVYKHLVEDILSSSSQWSA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.. .****:**::****:********. * **** ******:*: **.****:* **:*:*.* ***:*:****:** .**:****************::**********.****:**:*******************:** *:**************. .:.* ***** ***********:*:**********:***.*:********** *.**:** ****. *:**********:**:*****:*:::::**:***:::.*. *:**:** .: *:*:**:**::* .:..:* :*:* *:**::*********** :*:*.**: . . ..:. :. : : . . * * :: : :*. *:..: * : * . : : .: *** . . .: : * :. *: *.. : : :* : ::* .: . *. .. :* : :. . * .:*****.** :** .:::. *:** :************:* ** .*::* .:****: * :**** *. .*.**:*.:*::***:*:************:***************** **:*:*****************:*******... ", "identical_positions": 352, "similar_positions": 168, "identity": "50.14%" }, { "cls_id": "homologset.agr.RGD:1308975", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9UKR0-1", "uniprot_id": "KLK12_HUMAN", "id": "Q9UKR0-1", "name": "Kallikrein-12", "aln": "--------------------------------------------------MGLSIFLLLCVLGLSQAA----------TPKIFNGTECGRNSQPWQVG--LFEGT-SLRCGGVLIDHRWVLTAAHCSGS--RYWVRLGEHSLSQLDWTEQIRHSGFSVTHPGYLGASTSHEHDLRLLRLRLPVRVTSSVQPLPLP--NDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCH--GVYPG-RITSNMVCAGGVPG-QDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYTYICKYVDWIRMIMRNN--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZD22-1", "uniprot_id": "D3ZD22_RAT", "id": "D3ZD22-1", "name": "", "aln": "--------------------------------------------------MKLNILLLLCVVGLSQAD----------REKIYNGVECVKNSQPWQVG--LFHGK-YLRCGGVLVDRKWVLTAAHCSG---KYMVRLGEHSLSKLDLTEQLRLTTFSITHPSYHGAYQNHEHDLRLLRLNRPISLTYAVRPVALP--SSCAPTGAKCHISGWGTTNKPWDPFPDRLQCLDLSIVSNETCR--AVFPG-RVTENMLCAGGEAG-KDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQKGIPGVYTKVCKYTDWIRVVIRNN--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0AB32TXS7-1", "uniprot_id": "A0AB32TXS7_DANRE", "id": "A0AB32TXS7-1", "name": "trypsin", "aln": "--------------------------------------------------MILCCFEPVNEENNEKDPELVCEGLDFVQGRIVGGYSPSPNSIKYIVS--LQSSKGQHFCGGSLVHKYWVLTAAHCNIGMDQMMVVAGDYTLGANEGTEQYSKPLMLIPHPLYN--RSTNNADIMLIKLSAPIELNRYVSLAPLPKQNTGLLAGRMCRVSGWGSTSHSGGLIPLTLRTVRLPIVSTFKCNSSSSFSG-NITANMICAGSSTGGKDACKGDSGGPLVCDGRVYGLVSWGNG--CGDPRFPGVYTAVSRFRRWIDQTIYSTYARCLKSAGLFGKD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1ZA64-1", "uniprot_id": "A1ZA64_DROME", "id": "A1ZA64-1", "name": "trypsin", "aln": "----------------------------------------------MSLRLGLFLLAALGVVILTDSAS--------ISTHIVGGDQADIADFPYQVSVRLETYMLLHICGGSIYAPRVVITAAHCIKGRYASYIRIVAGQNSIADLEEQGVKVSKLIPHAGYN--KKTYVNDIGLIITREPLEYSALVQPIAVA--LEAPPSGAQAVVSGWGKRAEDDEALPAMLRAVELQIIEKSTCGAQYLTKDYTVTDEMLCAGYLEGGKDTCNGDSGGPLAVDGVLVGVVSWGVG--CGREGFPGVYTSVNSHIDWIEEQAEAYL-------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VS87-1", "uniprot_id": "Q9VS87_DROME", "id": "Q9VS87-1", "name": "Peptidase S1 domain-containing protein", "aln": "MTSNLSGIVVIANLWILVVGGQSKNWSGYYVDNGTHYLLYEGPRIKPQTFLPGNISTNPAINALEAQDY--------LPTRIVNGKKIKCSRAPYQCA---LHYNNYFICGCVILNRRWILTAQHCKIG-NPGRYTVRAGS-TQQRRGGQLRHVQKTVCHPNYS--EYTMKNDLCMMKLKTPLNVGRCVQKVKLPS-TRTKRFPKCYLASGWGLTSANAQNVQRYLRGVIVCKVSRAKCQQDYRGTGIKIYKQMICAK--RKNRDTCSGDSGGPLVHNGVLYGITSFGIG--CASAKYPGVYVNVLQYTRWIKKVAKKY--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IQ89-1", "uniprot_id": "Q8IQ89_DROME", "id": "Q8IQ89-1", "name": "Peptidase S1 domain-containing protein", "aln": "MYQNFGSESEGR--------ERDPSWSGYYKDNGTHYLLYGKPEDIAPTPNFGNISSNPFINALEAQES--------FPTRIVNGKRIPCTEAPFQGS---LHYEGYFVCGCVIINKIWILTAHHCFFG-PPEKYTVRVGS-DQQRRGGQLRHVKKIVALAAYN--DYTMRHDLAMMKLKSPVYFGKCVRPVKLPS-TKTTKFPKKFVVSGWGITSANAQNVQRYLRRVQIDYIKRSKCQKMYKKAGLKIYKDMICAS--RTNKDSCSGDSGGPLTSRGVLYGIVSWGIG--CANKNYPGVYVNCKRYVPWIKKVIHKY--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VQ98-1", "uniprot_id": "Q9VQ98_DROME", "id": "Q9VQ98-1", "name": "trypsin", "aln": "--------------------------------------------------MFVQWIFLAFSVTVVSSNW--------IPERIVGGDLITILSVPWQAS---ILRLGRFHCGAAIYSEDIVITAAHCLTDRETEFLSVRVGS-SFTFFGGQVVRVSSVLLHEEY---DQSWSNDIAVMRLQSKLRLGSAVSVIPLAD-TPPASG-SPATVSGWGAIGFKKNYPMSILS-ASVDIVDQDQCRRSY---GRKITKDMICAA--APGKDACSGDSGGPLVSGNKLVGIVSFGKE--CAHPEYPGVYANVAELKPWILGAIERITKSE----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* .* : . ** : ::** ** * : * . *: :: : * :. **** * : :. * . : :*:** :*:*.*******. . : *:.*:* *. ****. ** ", "identical_positions": 40, "similar_positions": 33, "identity": "12.01%" }, { "cls_id": "homologset.agr.RGD:1308976", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "F1LRA5-1", "uniprot_id": "F1LRA5_RAT", "id": "F1LRA5-1", "name": "", "aln": "MGWKILPICLSMLLPVFLIQQVSSQDISSCAGRCGEGYSRDATCNCDYNCQHYMECCPDFKRVCTTELSCKGRCFESFARGRECDCDSQCKQYGKCCADYNSFCEEVHNPTSPPP-KTAPPPPGASRTIKSTTKRSPKSP-KKKTKKVVESEEITEEHSVSENQESSSSSSSSSS--TIRKIKSSKN-SANRELQKNPKVKDNKKNTPKKKPNPEPPVVDEAGSGLDNGEPKLTPPP-DPP-TPHNKVTASPKTTAAKPVTPKPSLAPNSETSKEASSTSNKETTVETKETTETNKQSSASKKEKTTSAKETRSAENTSAKDVEPTS-----------TTPKNSAPTTTKKP-VTTTKEPVPTTTKGPEPTSKEPAPTTPKEPELTIPKEPAPTTKKPAPTTPKEPAPTTPKEPEPTTPKESA-------PTTPKEPAPTTPKEPAPTTPKEPAPTTPKEPAPTTPKEPAPTTKKPEPTTPKEPAPTTPKEPAPTTPKEPAPNTPKEPAPTTPKEPAPTTPKEPE----------------------STTPKEPAPTTPKEPAPTTPKEPAPTTPKEPAPTTPKEPAPTTPKEPAPTTPKEPAPTTPKEPAPTTPKEPVPTTPK--------------------------------EPASTTPKEPAPTTPKEPAPTTPKEPAPTTPKEPAPTTPKEPAPTTPKEPALTTPK-EPAPTPKEPEPTTPKEPA-----------------------------PTTPKEPAPTTPKEPAPTTKK------PELTIPKEPVPTTPKEPAPTTPKEPAPTTTKKPELSTPKEPTSTNPKEPEPTLPKEPELTLPEEPEPSNPET---------------SDELIAELAEAPTPKALENNPKEPTVPT-ETPEVSKPEMTTAKEKTTEKDTTQTTTTVTPKTTTETTIIPEETTEPRASTTTRITSTAQDTTSPQMTTLKATTLAAKVTAPTEEIQSKPEETTLTTPALEGSDASKTTLKPQKPTKAPKKPASTKKPTKAPKKPTSTKKPK-TPKGRKPKTTPSPLKTSTMS-EQNTTP--LEVMLPTTTVPKQTPNSETAEVNPAHEDADGGEGEKP-LIPRPPVLSPTAVPGTDLLVERLNPGINIHPMFSDETNICNGKPVDGLTTLRNGTLVAFRGHYFWMLN-PFRPPSPPRRITEVWGIPSPIDTVFTRCNCEGKTFFFKDSQYWRFTNDVMDAGYPKLIVKGFGGLTGKIVAALSIAKYKDRPESVYFFKRGGNIQQYTYKQEPVRKCTGRQPAINYSVYGQAAQVRRRRFERAVGPFQTHTFRIHYSVPIKASYQDKGFLHNEVKVSTLWRGFPNVVTSAITLPNIRKPDGYDYYAFSKDQYYNIDVPTR---TARAITTRSGQTLSRVWYNCP-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JM99-1", "uniprot_id": "PRG4_MOUSE", "id": "Q9JM99-1", "name": "Proteoglycan 4", "aln": "MGWKILPVCLSLLLPVVLIQQVSSQDLSSCAGRCGEGYSRDATCNCDYNCQHYMECCPDFKRVCSPELSCKGRCFESFARGRECDCDSQCKQYGKCCADYDSFCEEVHNSTSPSS-KTAPTPAGASDTIKSTTKRSPKSP-TTRTIKVVESEELTEEHSDSENQESSSSSSSSSS--TIRKIKSSKN-SANRELQKNPNVKDNKKNTPKKKPNPEPPAVDEAGSGLDNGEFKLTPPPPDPPTTPHSKVATSPKTTAAKPVTPKPSLAPNSETSKEASLASNKETTVETKETTATNKQSSASKK-KTTSVKETRSAEKTSDKDVEPTS-----------TTPKNSAPTTTKKP-VTTTKE------------SK--FLPLPQEPEPTTAKEPPPTTKKPEPTTRKEPEPTTPKEPEPTTPKE-------------------------------PEPTTPKEPEPTTPKEPPPTTKKPEPTTPKEPGPTTPKEPEPTTTKEPEPTTTKEPESTTRKEPEPTTPKEPE----------------------PTTPKEPEPTTLKEPEPTTPKEPEPTTPKEPEPTTPKEPEPTTPKEPEPTTPKEPEPTTPKEPEPTTPKEPEPTTPK--------------------------------EPEPTTPKKPEPTTPKEPVPTTPKEPEPTTPKEPEPTTPKEPEPTTRKE----------------PEPTTPKEPE-----------------------------PTTPKEPEPTTPKKPEPTT------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TSPKTTTLKATTLAPKVTAPAEEIQNKPEE---TTPASEDSDDSKTTLKPQKPTKAPKP---TKKPTKAPKKPTSTKKPK-TPKTRKPKTTPSPLKTTSATPELNTTP--LEVMLPTTTIPKQTPNPETAEVNPDHEDADGGEGEKP-LIPGPPVLFPTAIPGTDLLAGRLNQGININPMLSDETNLCNGKPVDGLTTLRNGTLVAFRGHYFWMLN-PFRPPSPPRRITEVWGIPSPIDTVFTRCNCEGKTFFFKDSQYWRFTNDVVDPGYPKQIVKGFGGLTGKIVAALSIAKYKDRPESVYFFKRGGNIQQYTYKQEPMKKCTGRRPAINYSVYGEAAQVRRRRFERAVGPFQTHTFRIHYSVPMRVSYQDKGFLHNEVKVSTMWRGFPNVVTSAITLPNIRKPDGYDYYAFSKDQYYNIDVPTR---TARAITTRSGQTLSKIWYNCP-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92954-1", "uniprot_id": "PRG4_HUMAN", "id": "Q92954-1", "name": "Proteoglycan 4", "aln": "MAWKTLPIYLLLLLSVFVIQQVSSQDLSSCAGRCGEGYSRDATCNCDYNCQHYMECCPDFKRVCTAELSCKGRCFESFERGRECDCDAQCKKYDKCCPDYESFCAEVHNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPD--TSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTSDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTIT---TTEIMNKPEETAKPKDRATNSKATTP--KPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGETPHMLLRPHVFMPEVTPDMDYLPRVPNQGIIINPMLSDETNICNGKPVDGLTTLRNGTLVAFRGHYFWMLS-PFSPPSPARRITEVWGIPSPIDTVFTRCNCEGKTFFFKDSQYWRFTNDIKDAGYPKPIFKGFGGLTGQIVAALSTAKYKNWPESVYFFKRGGSIQQYIYKQEPVQKCPGRRPALNYPVYGETTQVRRRRFERAIGPSQTHTIRIQYS-PARLAYQDKGVLHNEVKVSILWRGLPNVVTSAISLPNIRKPDGYDYYAFSKDQYYNIDVPSR---TARAITTRSGQTLSKVWYNCP-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PHS8-1", "uniprot_id": "A0A8M1PHS8_DANRE", "id": "A0A8M1PHS8-1", "name": "", "aln": "---MTGLTVLWSLLALLCTVLPSSAAQGSCVGRCGEQFSRGHICNCDYNCFVHGECCKDFEDICTASESCRGRCGEPFRRGRQCECDSGCVLHNSCCPDYSTHCDAFSHLQAPRSS---KPNKPADYTEECIA--------------------------------------------ACLAAQQNPDVMRYGSGLNNLM---------------TPSASPFLAGDVSQDG----------PYT------------------------------------------------------------------------------------------------------------------------------------------------------------PLSASD---------------------------------------------------IPGLSSSPSEFHLAES-------------------------------------------------------------------------------------------------------DAAAPLQPAG----------------------------------------------------------------------------ASSENPQAVPVQVSLSISGQADRPSSSSGRPSIP----------------------------------------------------------------------ADIAQAPAD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SSPAGPG--------------------------------------------------------------------------------------------------------------LNLCSGVVIDGMAALFNGSIIVFRGHFFWLLNPKTRRAGPARRITEELGVPSPIDTAFTRCNCQGKTYIIKGDSYWSFENGVLESGYPRSVSQDFGGLSGDITAALPVPATRKRPESVYFFKKGGKVQKLSFPPGSGPNCSGK-RSKNADKP------------------------------SKNGKQAEIQLSGEINIKLKMKGFPSAVSSAVSMPNPRKSDGFDYLVFSWPKVLNVKISGDLPALTAPASHSSQQNDITKWLHCA-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58I2W8-1", "uniprot_id": "A0AC58I2W8_DANRE", "id": "A0AC58I2W8-1", "name": "", "aln": "------MATYLSVLLLFVWVSTSSSNPRSCGGRCGEGYYRGSFCQCDYDCLGLNECCADFQDLCTSKDSCKGRCGEPFNRGNPCHCDIDCVSYNQCCPDYESMCLIEAYISVTVTDSALKPRNTASAAQRIAN--------------------------------------------LCLNIKNKKSTESSNEEMTNLEGTGDEFTVPEYETEPTPSEGRDVPAEILPEG----------PYTGSDIEEKQKENSTFHPENETSSPAPSTPTADVSSIFPADENHIDFTTQQPSEELTASSTLQPQENSSIALTEGPTSVTPVDDSP---------------------------------------------------------EEDPKKQTITVDPTSPVPAEDP-------------------------------------------------TSPGLAEDPTSPGPAEDPISPVPAEDPTSPGPAEDPISPVPAEDPTSPVPAEDPISPVPAEDPTSPVPAE-----------------------------------DPTSTVAPEDPNNQTPAENPTSPAATADPTDQNPAEDPRNPAPAEDSRKPAPTEDPTSMAPTEG---------------------------------STSAAPTENLTTAPTEGATPVPRKTPAPMKPTKKPTQPSKE---------------------------------------------------------------NIDKSEVKESPKDPVVISPI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RVTEKPLKPSSDLNGR--------------------------------------------------------------------------------------------TDILDYQSDDYDSNLCSGRPVSGLTTLRNGTIVVFRGHYFWTLD-KQRNPDPPQLITQVWGIPSPIDTVYTRCNCQGKTYFFKGKNYWRFENGAMDPGFPKPISEGFG-QIGHITAALSIPEYRSRKESVIFFKRGGMAQKYTYQVT--PNCGRRPKIPVITVR------------------------------MRTRRQTAAALGQVINISRTWRGFPTMVTSSVSVPS-RVKEGYKYYVFSQRNYYSMKMERDKPVILKPVTGP-KENPATSFFKCKDTQKI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* :. ** ** ***** : *. *:***:* *** **: :*:.. **:*** *.* **. *.** * :..**.**.: * . . . *. : . :.. . . .: *. . : . * * . .: * . .: . * * :. : :.* . :. . *: * :* . . * * *:*.* :.*:::* **:::.****:** *. ..*.: **: *:******.:*****:***:::*...** * *. :.*:*: : :.** *.*.***. . :. *** ***:** *: : :* : : * * :::. :*:*. *:*::::*. * :*:.* .** : .:.: . : :. : :* ", "identical_positions": 122, "similar_positions": 135, "identity": "8.59%" }, { "cls_id": "homologset.agr.RGD:1308977", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "B9TQX4-1", "uniprot_id": "UCMA_RAT", "id": "B9TQX4-1", "name": "Unique cartilage matrix-associated protein", "aln": "MSWRQVILLSSLSALVLLCMLQEGTSASVGSRQAAGEEVQEGMKQKIFMQESDASNFLKRRGKRSPKSRDEVTAENRQKLRDDELRREYYEEQRNEFENFVEEQRDEQEERTREAVEQWRQWHYDGLYPSYLYNRQNI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14BU0-1", "uniprot_id": "UCMA_MOUSE", "id": "Q14BU0-1", "name": "Unique cartilage matrix-associated protein", "aln": "MSWRRVILLSSLLALVLLCMLQEGTSASVGSRQAAAEGVQEGVKQKIFMQESDASNFLKRRGKRSPKSRDEVNAENRQRLRDDELRREYYEEQRNEFENFVEEQRDEQEERTREAVEQWRQWHYDGLYPSYLYNRQNI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WVF2-1", "uniprot_id": "UCMA_HUMAN", "id": "Q8WVF2-1", "name": "Unique cartilage matrix-associated protein", "aln": "MTWRQAVLLSCFSAVVLLSMLREGTSVSVGTMQMAGEEASEDAKQKIFMQESDASNFLKRRGKRSPKSRDEVNVENRQKLRVDELRREYYEEQRNEFENFVEEQNDEQEERSREAVEQWRQWHYDGLHPSYLYNRHHT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NWB6-1", "uniprot_id": "UCMA_DANRE", "id": "Q6NWB6-1", "name": "Unique cartilage matrix-associated protein", "aln": "MSWTQPALLTCLLVLSAITLFDGADSAVSDKRDAVNP---QGALRKIFMPEADAASFFKRRSRRAVKTQDEINAEQRQRLAADERRREYHEEQRNKYENYAEEENDEQDERTREKTEQWREFHYDGLDPSYEYNRHTI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:* : **:.: .: : :: . *. .. : . :. :**** *:**:.*:***.:*: *::**:..*:**:* ** ****:*****::**:.**:.***:**:** .****::***** *** ***: ", "identical_positions": 61, "similar_positions": 46, "identity": "44.2%" }, { "cls_id": "homologset.agr.RGD:1308978", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q4FZR8-1", "uniprot_id": "Q4FZR8_RAT", "id": "Q4FZR8-1", "name": "Four and a half LIM domains protein 1", "aln": "-MSEFKCHHCRESLQGKKYVQKDNFNYCVTCFDAHCANICVECNKPIGADSKEVCYKERFWHNTCFKCSKCLQPLATETFVVWDNKILCNNCVSQQAFPKCKGCLKDIKQGEQSVEYKGTIWHKDCFVCS-NCKEVIGTKTFFPKDEGFYCVACYDILFTKYCVKCNKPITSGGVSYQDQPWHSECFVCVNCSKELSEQRFTVMDDKIFCVDCYKNFIAKKCAGCKNPITGFGKGSNVVTHETNSWHDYCFNCKACSVNLANKHFVFHQEQIYCPDCAKKLA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VIE3-1", "uniprot_id": "Q9VIE3_DROME", "id": "Q9VIE3-1", "name": "LIM zinc-binding domain-containing protein", "aln": "MTESIVCHKCQEAITKRMITALG-----------------------------------KTWHPEHFLCHHCDEQILDATFNVQSGEPVCNKCFVERYTYTCAGCKKPIL--EKTICAMGERWHEACFCCGGACKKPLASQTFYERDGKPYCKQDYENLFAARCAKCEKPITDSAVLAMNVKWHRNCFQCNKCENPITSQTFTIDGDKPVCPACNC-------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..: **:*:*:: : . . : ** * * :* : : ** * ..: :**:*. :: .* ** * * *::: * **: ** *. **: :.::**: :* ** *: **: *.**:****...* : ** :** * :*.: ::.* **: .** .* * ", "identical_positions": 58, "similar_positions": 53, "identity": "20.57%" }, { "cls_id": "homologset.agr.RGD:1308979", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9H2A9-1", "uniprot_id": "CHST8_HUMAN", "id": "Q9H2A9-1", "name": "Carbohydrate sulfotransferase 8", "aln": "MTLRPGTMRLACMFSSILLFGAAGLLLFISLQDPTELAPQQVPGIKFNIRPRQPHHDLPPGGSQDGDLKEPTERVTRDLSSGAPRGRNLPAPDQP-QPPLQRGTRLRLRQRRRRLLIKKMPAAATIPANSSDAPFIRPGPGTLDGRWVSLHRSQQERKRVMQEACAKYRASSSRRAVTPRHVSRIFVEDRHRVLYCEVPKAGCSNWKRVLMVLAGLASSTADIQHNTVHYGSALKRLDTFDRQGILHRLSTYTKMLFVREPFERLVSAFRDKFEHPNSYYHPVFGKAILARYRANASREALRTGSGVRFPEFVQYLLDVHRPVGMDIHWDHVSRLCSPCLIDYDFVGKFESMEDDANFFLSLIRAPRNLTFPRFKDRHSQEARTTARIAHQYFAQLSALQRQRTYDFYYMDYLMFNYSKPFADLY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LZD4-1", "uniprot_id": "A0ABK0LZD4_RAT", "id": "A0ABK0LZD4-1", "name": "Carbohydrate sulfotransferase", "aln": "MTPRLGTMRLACMFSSILLFGAAGLLLFISLQDPIELSPQQFPGIKFSIRPQHPQHDS--------HLRIPTERVTRDSPSGSPRGLQLQAPDQPGSHPKAAGSPLRLRQRRRRLLIKKMPAAGTMRGNNSSETFIQPRPRTVDSRWLSLHQTQQERKRVMQEACAKYRASSSRRAVTPRHVSRIFVEDRHRVLYCEVPKAGCSNWKRVLMVLAGLASSTADIQHNTVHYGSALKRLDTFDRQGIVHRLSTYTKMLFVREPFERLVSAFRDKFEHPNSYYHPVFGKAILARYRANASREALRTGSGVQFPEFVQYLLDVHRPVGMDIHWDHVSRLCSPCLIDYDFVGKFESMEDDANFFLRLIHAPGNLTFPRFKDRHSEEARTTSRITHQYFAQLSSLQRQRTYDFYYMDYLMFNYSKPFSDLY", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** * ***************************** **:***.*****.***::*:** .*: ******** .**:*** :* ***** . * *: ******************.*: .*.*. .**:* * *:*.**:***::********************************************************************************************:*************************************************************:**************************************************** **:** ************:*****:**:********:***********************:***", "identical_positions": 364, "similar_positions": 33, "identity": "85.65%" }, { "cls_id": "homologset.agr.RGD:1308980", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K001-1", "uniprot_id": "A0A0G2K001_RAT", "id": "A0A0G2K001-1", "name": "Histone-lysine N-methyltransferase NSD3", "aln": "MDFSFSFMQGIMGNTIQQPPQLIDSAN-IRQEDAFDNNSDIVEDGGPTPFEATLQQGFQCPPATEDLP---PLTNGYPPSISLYETQTKYPPYSQYPNGSANGFGAVRN------FSPTDYYHSEIPNTRPHEILEKP----SPP-------------------------------------------------QPPPPPLLPPPPPPVPQ------------------TVIPKKTGSPEIKLKITKTIQNGRELFESSLCGD-LLNEVQASEHLKSKHESRKEKRKK-SSRHESSRSEERKSHKVPKLEPEGQNRPNE----------------------------RVDPAPEKPREEP------VLKEAVPVQPILSSVPTTETSTG--VKFQVGDLVWSKVGTYPWWPCMVSSDPQLEVHTKINTRGAR----------EYHVQFFSNQPERAWVHEKRVREYKGHEQYEELLAEAAKQASNHSEKQKIRKPRPQRERAQWDIGIAHAEKALQMTREERVEQYTFIYIDKQP--------------EESPSQAKKSVTS-KAEVK-----KPRRPRSVGNSQPE-------------QTSAGEVASPQSSTDPRRQSQ-----RRHTSVEEDGPPPVKIAWRTAAARKSLPASITMHKGSLDLHKCNMSPVVKIEQVFALQNATGDGKFIDQFVYSTKGIGNKTEISVRGQDRLIISSPSQRNEKSTPSASPPEATSGSAGPVEKKQQRRSIRTRSESEKSTEVVSKKKIKKEQQVETSPQASLKTGLQKGASEISDSCKPLKKRSRASTDVETASCTYRDTSDSDSRGPSDGQVGFGKQVDSPSAAADADASDAQSVDSSLSRRGVGLSKKDTVCQVCENTGDSLVACEGECCRHFHPECLGLAAVPEGRFTCEECETGQHPCFSCKVSGKDVKRCSVSVCGKFYHEACVRKFPTAIFESKGFRCPQHCCSSCSMEK---DIHKASKGRMMKCLRCPIAYHFGDACVAAGSVSVSSHILICSNHS---KRSSHSAAINVGFCFVCARGLIVQDHSDPMFSSYAYKSHYLLSESNRAELMKLPMIPSSS-ASKKRCEKGGRLLCCESCPASFHPECLSIDMP-EGCWNCNDCKAGKKLHYKQIVWVKLGNYR---WWPAETCSPRSVPLNIQGLKHGVGDFPVLFFGSHDYYWVHQGRVFPYVEGDT-NFAEGQTSINKTFKKALEEAAKRFQELKAQRESKEALEIEKTSRKPPPYKHIKANKVIGKVQIQVADLSEIPRCNCKPGDENPCGLESECLNRMSQYECHPQVCPAGDRCQNQCFTKRLYPDAEIIKTERRGWGLRTKRSIKKGEFVNEYVGELIDEEECRLRIKRAHENSVTNFYMLTVTKDRIIDAGPKGNYSRFMNHSCNPNCETQKWTVNGDVRVGLFALCDIPAGMELTFNYNLDCLGN-GRTVCHCGADNCSGFLGVRPKSACTSAADEKTKNAKLK-KRRRGKAEAKQIHEDYCFQCGDGGELVMCDKKDCPKAYHLLCLNLTQPPYGKWECPWHQCDECGSAAISFCEFCPHSFCKAHEKGALVPSALEGRLCCSNHDPASPVSPEY-WSKMRCKWESQDG--GEEVKE---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P2L6-1", "uniprot_id": "NSD3_MOUSE", "id": "Q6P2L6-1", "name": "Histone-lysine N-methyltransferase NSD3", "aln": "MDFSFSFMQGIMGNTIQQPPQLIDSAN-IRQEDAFDNHSDIVEDGGPTPFEATLQQGFQYPPTTEDLP---PLTNGYPPSISLYETQTKYPPYNQYPNGSANGFGAVRN------FSPTDYYHSEIPNTRPHEILEKP----SPP-------------------------------------------------QPPPP-------PSVPQ------------------TVIPKKTGSPEIKLKITKTIQNGRELFESSLCGD-LLNEVQASEHTKSKHESRKEKRKK-SNRHESSRSEERRSHKIPKLEPEGQNRPNE----------------------------RVDTAPEKPREEP------VLKEAIPVQPILSSVPTTETSTG--VKFQVGDLVWSKVGTYPWWPCMVSSDPQLEVHSKINTRGAR----------EYHVQFFSNQPERAWVHEKRVREYKGHEQYEELLAEAAKQASNHSEKQKIRKPRPQRERAQWDIGIAHAEKALKMTREERVEQYTFIYIDKQP--------------EEASSQAKKNVTS-KTEVK-----KPRRPRSVLNSQPE-------------QTNAGEVASSQSSTDLRRQSQ-----RRHTSLEEEEPPPVKIAWKTAAARKSLPASITMHKGSLDLQKCNMSPVVKIEQVFALQNATGDGKFIDQFVYSTKGIGNKTEISVRGQDRLIISSPSQRSEKPAQSASSPEATSGSAGPVEKKQQRRSIRTRSESEKSAEVVPKKKIKKEQ-VETAPQASLKTGLQKGASEISDSCKPLKKRSRASTDVETASCTYRDTSDSDSRGLSDGQVGFGKQVDSPSATADADASDAQSVDSSLSRRGVGTSKKDTVCQVCEKAGDCLVACEGECCRHFHVECLGLTAVPEGHFTCEECETGQHPCFSCKVSGKDVKRCSVSVCGKFYHEACVRKFPTAIFESKGFRCPQHCCSSCSMEK---DIHKASKGRMMRCLRCPVAYHVGDACVAAGSVSVSSHILICSNHS---KRSSQSAAINVGFCFVCARGLIVQDHSDPMFSSYAYKSHYLLSESNRAELMKLPMIPSSS-ASKKRCEKGGRLLCCESCPASFHPECLSIDMP-EGCWNCNDCKAGKKLHYKQIVWVKLGNYRQVLWWPAEICSPRSVPLNIQGLKHDLGDFPVFFFGSHDYYWVHQGRVFPYVEGDK-HFAEGQTSINKTFKKALEEAAKRFQELKAQRESKEALEMERTSRKPPPYKHIKANKVIGKVQVQVADLSEIPRCNCKPGDENPCGLESQCLNRMSQYECHPQVCPAGDRCQNQCFTKRLYPDAEVIKTERRGWGLRTKRSIKKGEFVNEYVGELIDEEECRLRIKRAHENSVTNFYMLTVTKDRIIDAGPKGNYSRFMNHSCNPNCETQKWTVNGDVRVGLFALCDIPAGMELTFNYNLDCLGN-GRTVCHCGADNCSGFLGVRPKSACTSAVDEKTKNAKLK-KRRKVKAEAKPIHEDYCFQCGDGGELVMCDKKDCPKAYHLLCLNLTQPPHGKWECPWHRCDECGSVAVSFCEFCPHSFCKAHGKGALVPSALEGRLCCSSHDPASPVSPEY-WSKIRCKWESQDS--GEEVKE---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BZ95-1", "uniprot_id": "NSD3_HUMAN", "id": "Q9BZ95-1", "name": "Histone-lysine N-methyltransferase NSD3", "aln": "MDFSFSFMQGIMGNTIQQPPQLIDSAN-IRQEDAFDNNSDIAEDGGQTPYEATLQQGFQYPATTEDLP---PLTNGYPSSISVYETQTKYQSYNQYPNGSANGFGAVRN------FSPTDYYHSEIPNTRPHEILEKP----SPP-------------------------------------------------QPPPP-------PSVPQ------------------TVIPKKTGSPEIKLKITKTIQNGRELFESSLCGD-LLNEVQASEHTKSKHESRKEKRKK-SNKHDSSRSEERKSHKIPKLEPEEQNRPNE----------------------------RVDTVSEKPREEP------VLKEEAPVQPILSSVPTTEVSTG--VKFQVGDLVWSKVGTYPWWPCMVSSDPQLEVHTKINTRGAR----------EYHVQFFSNQPERAWVHEKRVREYKGHKQYEELLAEATKQASNHSEKQKIRKPRPQRERAQWDIGIAHAEKALKMTREERIEQYTFIYIDKQP--------------EEALSQAKKSVAS-KTEVK-----KTRRPRSVLNTQPE-------------QTNAGEVASSLSSTEIRRHSQ-----RRHTSAEEEEPPPVKIAWKTAAARKSLPASITMHKGSLDLQKCNMSPVVKIEQVFALQNATGDGKFIDQFVYSTKGIGNKTEISVRGQDRLIISTPNQRNEKPTQSVSSPEATSGSTGSVEKKQQRRSIRTRSESEKSTEVVPKKKIKKEQ-VETVPQATVKTGLQKGASEISDSCKPLKKRSRASTDVEMTSSAYRDTSDSDSRGLSDLQVGFGKQVDSPSATADADVSDVQSMDSSLSRRGTGMSKKDTVCQICESSGDSLIPCEGECCKHFHLECLGLASLPDSKFICMECKTGQHPCFSCKVSGKDVKRCSVGACGKFYHEACVRKFPTAIFESKGFRCPQHCCSACSMEK---DIHKASKGRMMRCLRCPVAYHSGDACIAAGSMLVSSYILICSNHS---KRSSNSSAVNVGFCFVCARGLIVQDHSDPMFSSYAYKSHYLLNESNRAELMKLPMIPSSS-ASKKKCEKGGRLLCCESCPASFHPECLSIEMP-EGCWNCNDCKAGKKLHYKQIVWVKLGNYR---WWPAEICNPRSVPLNIQGLKHDLGDFPVFFFGSHDYYWVHQGRVFPYVEGDK-SFAEGQTSINKTFKKALEEAAKRFQELKAQRESKEALEIEKNSRKPPPYKHIKANKVIGKVQIQVADLSEIPRCNCKPADENPCGLESECLNRMLQYECHPQVCPAGDRCQNQCFTKRLYPDAEIIKTERRGWGLRTKRSIKKGEFVNEYVGELIDEEECRLRIKRAHENSVTNFYMLTVTKDRIIDAGPKGNYSRFMNHSCNPNCETQKWTVNGDVRVGLFALCDIPAGMELTFNYNLDCLGN-GRTECHCGADNCSGFLGVRPKSACASTNEEKAKNAKLKQKRRKIKTEPKQMHEDYCFQCGDGGELVMCDKKDCPKAYHLLCLNLTQPPYGKWECPWHQCDECSSAAVSFCEFCPHSFCKDHEKGALVPSALEGRLCCSEHDPMAPVSPEY-WSKIKCKWESQDH--GEEVKE---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B1N3-1", "uniprot_id": "A0A8M2B1N3_DANRE", "id": "A0A8M2B1N3-1", "name": "Histone-lysine N-methyltransferase NSD3", "aln": "MDFSFSFMQGIMGNTIQQPPQLIDSAN-IRQEDVYEAISDPGDDGGQQNFDSPLESGFSYP--AEDVP---VITNGYPTGVGTYEQQAKFALYSQFPNGSANGYGAIRN------YGDHSLLLGEGTVLRPPVVQEKPQTHISPPSHSHHHQQPHHPHHHHHQQQQQHHPHNPPLLPHHHHHHPPPASHLMPQVLPPPPPLLLPSSPPLLSPQESTISNPIGQPVNTIITTTPKKTSSPEIKLKIIKTYQNGRELFESSLCGD-LLQEFQAGEDSRRQHEQKKEKRKKRGSRHGAGQEESQQPSKVEEERSVVVHNPVQ----------------------------TTESQVAFREEQQPQSSLKSPKAELKEQKVEKHCPSVITSTGTSQEYEIGDLVWAKVGTYPWWPCMVSSDPQSNVHTRINTRGCK----------EYHVQFFGSVPERAWIHEKRTVVYKSENQFDELQAETLRKSTNPTEKQKLLKPQSQKERAQWEVGVGHAEAALQMTREERNENYTFIYIDKEPGADAETAAAPAPAPDSAPTAPTDTVTSPKATAKNRPERKQRRSRGSAGAKEEPIPRRQQPRRQCSMNSVGETSSPNQGEDAMEQEQPCSPPKPAPRPKEPSPPPVRTPWRTAAARKLLPLSITMKKLNVEIIKCDWQ---LPKQKVELPKKTESEERPSSRVKSPEGSSNKAEAETCSSEEERAASPSGWSDQEHTSAEQS---------TERKQQRRSVRSRSESEKSVEPVPKKKVKKEQ-AETAPQMDFKTGSQKGASEISDSCKPLKKRSRASTDVEMASSLYRDTSDSDSRGLNDPQTGFGKRSDSP-ATVDADGSDAQSVDSSLSRQGGSSSKKDTVCHVCETFGDSLVSCEGDCNRLFHPECMGSNSGKESETVCQECKTGSHPCFSCKVTEGDMKRCSVNGCGRYYHETCVRKYTGSASDTKGLRCPQHSCATCCLDR---DLQKAGKGRMMRCIRCPVAYHTGDGCVAAGSVLITPHIIICSNHSSSRKNGHFSSPVNVGWCFICARGLLVHDHTDTILSSYTFKSHYLLTESNRAELMKLPMIPSSSSATKKNIGKGGRLLCCEACPASFHPECLKIEMP-EGTWLCGECKSGKKPHYKQIVWVKLGNYR---WWPAEICNPRLVPSNIQSLKHDIGDFPVFFFGSHDYYWINQGRVFPYVESDK-NFAEGQVGINKTFKKALEEAAKRFQELKAQRETKEALEQERNSRRPPPYKLIKSNKPFGKVQLHVADLSEIPRCNCKPTDERPCSQDSQCLNRMLQYECHPQVCPAGDRCHNQCFSKRLYPDTEVIKTTGRGWGLKTKQDLKKGDFVMEYVGELIDSEECKQRIRTANENHVTNFYMLTLTKDRVIDAGPKGNLSRFMNHSCSPNCETQKWTVNGDVRIGLFTLCDISADTELTFNYNLDCLGN-GRTSCHCGSENCSGFLGVKPKSAVVMEREEKVRNAKLKPKKRKLKTESKQTHELYCYCCGEGGELVMCDKKDCPKAYHLLCLNLSKPPYGRWECPWHQCSVCQRTATSFCHFCPASFCREHERGQLAVSALDKQPCCSNHDPKRPLGPQANRSQVTVKKEPLDGNANEEEEEEEEETGDGE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8MT36-1", "uniprot_id": "NSD_DROME", "id": "Q8MT36-1", "name": "Nuclear receptor binding SET domain protein", "aln": "MKLSTDAHSEIEGDAAHGNVLCNSASDSLTATDEVAAGNDESVATEGDDVEIPRDTNNSTPVRLLDKPGQNPVQNGAQPAAEESELESQRQTPVQKQQQQRVSMVNRKRDLINLQSALSPKYIGYANANSPTPLSDSDDTIRTTRRRVNQAAALNNSSAGETLAHDNASPRTPGGGGGGGGDDSANQLLSKTYMSPIEKLLIKNGASSPNSTGFEAGSEDLGIRPIVRKHVKRKMKRVPKAKVTLELDEKNQQEVDEKSVKTEPIDEEVDRTDEAPTQEAQTTAISIKSETEAEHKAAVDVHIKQEDTIRLDIVNNPVESTSIVITEEPKDLEKSTEELAFALPLASSTEVDLKSPPDLSSTALATSIKSPSSVSIDSAKGLSIVTDPG-WPTYQVGDLFWGKVFSYCFWPCMVCPDPLGQIVGNMPSHPQRSSLDNANVPIQVHVRFFADNGRRNWIKPENLLTFAGLKAFDDMREELRIKHGPKSAKYRQMVPKR-TKVVIWRQAIEEAQAMTQIPYSDRLEKFYQTYENVVT-------------LNRQKRKRTKYMMQDTSDVG------SSLYDSTDNLHNK-------------QGTQLLAVKRERSESPFSPAFSPVKSKNEKRAKRRKLSNGTEADTGSNSMAVTPSQTETTVDSSAYENPEFRQLLSAVMEYVMMNRS-DEKVEKVLLSVVSNIWSLKQIQLRELERDLASG-----EIEEPLGSSVVGRGSGVGTIKRLSNRLMTMMVRRSMTPVVTPSTTPAPSEPDRRLSEPPKTKKPVNRPIEEVIEDILQLDSKYLFRGLSREPICKYCYQAGSDLVRCSRTCSSWLHADCLERKVTGAPMPKIGSRKALVIPPTSKSPSPDEDHVTADAKEVVAVGTSLVCHECNVGEPEGCVICHQVESPAVPSTPRKEDSSSHTPIEDKLLTCSQPMCGKRFHTSCCKYWPQASSSKHSARCPRHVCHTCVSDDPSGKFQQLGSSKLAKCVRCPATYHQLSKCIPAGTQMLNTTNIICPRHN----IAKADAHVNVLWCYICVK--------------------------------------------------GGELVCCETCPIAVHAHCRNIPIKTNESYICEECESGRLPLYGEIVWAKFNNFR---WWPAIILPPTEVPSNILKKAHGENDFVVRFFGTHDHGWISRRRVYLYIEGDTGDGHKTKSQLFRNYTTGVEEASRFLPIIKARRQEQDMERQSGNKLHPPPYVKIKTNKAVPPLRFSQN-LEDLSTCNCLPVDEHPCGPEAGCLNRMLFNECNPEYCKAGSLCENRMFEQRKSPRLEVVYMNERGFGLVNREPIAVGDFVIEYVGEVINHAEFQRRMEQKQRDRDENYYFLGVEKDFIIDAGPKGNLARFMNHSCEPNCETQKWTVNCIHRVGIFAIKDIPVNSELTFNYLWDDLMNNSKKACFCGAKRCSGEIGGKLKDDAVKAHAKLKQMRRAKASAVRIHVKPKKTPKVKHISADDEP----MDAKDE------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.:* . . * *:: : .::: : * .* : . : . . * * * : ** .. * ::: * : . . :. . . * : :. :. * .. . . * . *: *:.: :* :*: *.*: : : :*.: :. :. . . * .. . : : . :.* : .: : * . : ...* :::***.*.** :* :*****..** :: .: :: : : **:**.. .* *:: :. : . : :::: * : : * : *: : . * .: .*: ::. .:* *:: * : . : .. : . .: . . . : : . . . . . : :. . . : : * . . : : : : : . : . : .. . : . :. : : . :: .:* .* ... ... .* . *. :: .*: :. *..: . . . * :.** . .: : ...* .. * .: : .. * .: : . * . * * : . . . . .. . * . .: ** **: :* :* : :. : ..:. ***:* * :* : .::: ...:: :*:*** :** . *:.**: :.. :**..*. . .: :** :*::*.: **.*:***:** :.*..* .* : : : * :*::*: * :***.*:.*:* **** * ** ** *. .** * ***:**: *: : **: *:*.*. : : : :.:...:***:: : :**:*: :: . . .. :**** **:** . ::. *.::. *** * **.**. :: ***** **:*: * **. *.*: * :* * *:: **:** .:. : *:** *****:*: * : *:. :.: *:*:* : ** :******** :*******.*********** *:*:*:: **... ****** * * * .:. *.**:..*** :* : *. . : : : * . : :.:.* : ..: * ** ", "identical_positions": 258, "similar_positions": 403, "identity": "15.76%" }, { "cls_id": "homologset.agr.RGD:1308981", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZAD9-1", "uniprot_id": "D3ZAD9_RAT", "id": "D3ZAD9-1", "name": "", "aln": "MVDT--SGYGLLKHLRKLSDGEFWSFKELLRKEPEKFKLKPISWMKIENASKEELVMLLNTHYPK-QAWDMALSLFLQVNREDLSIMAQKKRRYKQTKYKKFMKTTFQSIWTLESNICIPDRSYHLIVEHQYRKLQNIFDSESEPVTAVVTGPTGEGKTVFLRKAMLDWASGILWQNRFQYVFFFSVLSLNNTTELSLAELISSKLPESSETLNDILSDPKKILFILDGFDYLKFDLELRTNLCNDWRKILPTQIILSSLLQKIMLPESSLLLELGHISLPKIFPLLQYPRDITIQGFSERCLKTYFISFFNTE-KGIEVFENLKSNQ-MLKLCSNPYLCWMFCSCLKWQFDREEEAYFQAKTDSVFFTSFMVSAFKSAYASNPPKQNRAQLKSLCTLAVEGMWKQLFVFDSEDLRRNGISESDKAVWLRMKFLQNHDNHIVFYHPTLQLYFASMFYFLKQDKDTHVPVIGSIPQLLRKIYARDHTQWLQIGIFLFGLATEQVASLLKPYFGFIQHRDVRQEVMRYLKSLSQRECCEKL-ERPQNLFACLRDNKEEKFVREVVDLFEEITVDITNSHVLSIIANHLQKSSKLKKLHLHIQKRVFLEIHDPEYSDSETFTQDKKNAAEYWKKLCHIFVNLHVLDLDSCNFNKQVIEELCNVLSPSPKIPLMAFKLESLLCSFMTNFGDGSLFHTLLQLPHLKYLNLYGTNLSNSRIENLCSALRRSTCKVEELLHSEMSFPLSTDFIVSHKFGLGKCDISSEACGIIATSLMN-SKVKHLSLVENPLKNKGVMSLCEMLKDPSCVLETLMLSYCCLTFIACGHLYEALVSNKHLSLLDLGSNFLEDTGVNLLCEALKDPNCILKELWLSGCFLTSECCEEISAVLTCNNNLKTLKLGNNDIEDTGVKHLCEALSHPNCKLECLGLDLCKFTSDCCEDLASALTTCKTLNSLNLDWKTLEHSGVVALCEALNHKKCNLKMLGLDKSAFSVESQTLLQAVEKKNNNLSILHYPWVEEERKKRGVRLVWNSKN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q66X22-1", "uniprot_id": "NLR9B_MOUSE", "id": "Q66X22-1", "name": "NACHT, LRR and PYD domains-containing protein 9B", "aln": "MAGS--SGYGLLKLLQKLSDEEFQRFKELLREEPEKFKLKPISWTKIENSSKESLVTLLNTHYPG-QAWNMMLSLFLQVNREDLSIMAQKKKRHKQTKYKKFMKTTFERIWTLETNTHIPDRNYHLIVEVQYKALQEIFDSESEPVTAIVAGTTGEGKTTFLRKAMLDWASGVLLQNRFQYVFFFSVFSLNNTTELSLAELISSTLPESSETVDDILSDPKRILFILDGFDYLKFDLELRTNLCNDWRKRLPTQIVLSSLLQKIMLPGCSLLLELGQISVPKIRHLLKYPRVITMQGFSERSVEFYCMSFFDNQ-RGIEVAENLRNNE-VLHLCSNPYLCWMFCSCLKWQFDREEEGYFKAKTDAAFFTNFMVSAFKSTYAHSPSKQNRARLKTLCTLAVEGMWKELFVFDSEDLRRNGISESDKAVWLKMQFLQTHGNHTVFYHPTLQSYFAAMFYFLKQDKDICVPVIGSIPQLLGNMYARGQTQWLQLGTFLFGLINEQVAALLQPCFGFIQPIYVRQEIICYFKCLGQQECNEKL-ERSQTLFSCLRDSQEERFVRQVVDLLEEITVDISSSDVLSVTAYALQKSSKLKKLHLHIQKTVFSEIYCPDHCKTRTSIGKRRNTAEYWKTLCGIFCNLYVLDLDSCQFNKRAIQDLCNSMSPTPTVPLTAFKLQSLSCSFMADFGDGSLFHTLLQLPHLKYLNLYGTYLSMDVTEKLCAALRCSACRVEELL-------------------LGKCGISSKACGIIAISLIN-SKVKHLSLVENPLKNKGVMSLCEMLKDPSCVLQSLMLSYCCLTFIACGHLYEALLSNKHLSLLDLGSNFLEDTGVNLLCEALKDPNCTLKELWLPGCFLTSQCCEEISAVLICNRNLKTLKLGNNNIQDTGVRQLCEALSHPNCNLECLGLDLCEFTSDCCKDLALALTTCKTLNSLNLDWKTLDHSGLVVLCEALNHKRCNLKMLGLDKSAFSEESQTLLQDVEKKNNNLNILHHPWFEAERNKRGTRLVWNSRN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q66X03-1", "uniprot_id": "NLR9A_MOUSE", "id": "Q66X03-1", "name": "NACHT, LRR and PYD domains-containing protein 9A", "aln": "MMDS--SGYGLLQYLQKLSDEEFQRFKEHLRKEPEKFKLKPISWTKIKNTSKEDLVMQLYTHYPG-KAWDMVLSLFLQVNREDLSTMAQTERRDKQTKYKEFMKNTFQHIWTMETNTYIPDRSYHEFIEVQYRALQDIFDCESEPVTVVVSGSRGGGKTTFLRKAMLDWASRNLLQNRFQYVFHFSVFSLNNITELSLAELISSTLPESSETVDDILSDPKRILFILDGFDYLKFDLELRTNLCNDWRKKLPIQIVLSSLLQKIMLPECSLLLELGNASLSNIIPLLQYPREIIMSGFSEQTIEIYCVSFFNTQ-TGVEIFKNLKSIKPLFNLCRCPHLCWMICSTIKWQYERREVASRFGRTLGLLYTIFMVSAFKSTYARNPSKQNRARIRTLCTLAVEGMWKQVYVFDSDDLRRNGISESDKKVWLRMKFLQNQGSNIVFYHSTLQWYFAVLFYFL-QYKDTRHPVIGNLAQLLGEIYAHKQNQWFHTRILLFGMATEQVNSLLEPCFGCISSKEVRQEIIRYIKSLSQQECNEKLVVHPQNLFFCILDNQEERFVRQLMDRFEEMTVDISDVDDMSATPYCLHRAPKVKNLHLHIQKRVFLEIHDPEYGDLELFKLGQK-------------------------------------------------------CSFTTNFGDGLLFCTFLHLPHLKYMNLYGTNLSNDAVERLCSALKFSTCGVEELL-------------------LGKCDISSEACGIIAASLIN-SEVKHLSLVENPLKNKGVMSLCEMLKDPSCVLESLMLSYCCLTFIACGHLYEALLSNEHLSLLDLGSNFLEDTGVNLLCEALKDPNCTLKELWLPGCYLTSECCEEISAVLTCNTNLKTLKLGNNNIQDTGVKRLCEALCHPNCEMQCLGLDMCDFTSDCCEDLALVLTTCNTLKSLNLDWNAFDHSGLEMLCKALNHKACNLEVLGLDKSLFSEESQTLLQAVEKKNKNLKVLHFPWLKEELEKRGVRLVWNSKN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q66X01-1", "uniprot_id": "NLR9C_MOUSE", "id": "Q66X01-1", "name": "NACHT, LRR and PYD domains-containing protein 9C", "aln": "MVDS--SSYGLLQYFQKLSDEEFQRFKELLQKEQEKFKLKPLSWTKIKNTSKEDLVTQLYTHYPR-QVWDMVLNLFLQVNRKDLSTMAQIERRDKQNKYKEFMKNLFQYIWTSETNTYMPDRSYNTIIDRQYKALLDIFDSESDPATAVVLGTRGKGKTVFLRKAMLDWASGVLLQNRFQYVFFFSVFSLNNTTELSLAELISSKLPECSETLDDILSNPKRILFVLDGFDYLKFDLELRTNLCNDWRKRLPTQNVLSSLLQKIMLPECSLLLELGESSCSKIIPLLQNPREIIMSGLSEQSIYFYCVSFFKIQ-LGVEVFKDLKKNEPLFTLCSNPSMLWMICSSLMWGHYSREEVISSSESTSAIHTIFIMSAFKSIFGLGSSKYKRFKLKTLCTLAVEGMWKQVYVFDSEDLRRNKISESDKTVWLKMKFLQIQGNNIMFYHSTLQWYFATLFYFLKQDKDTYHPVIGSLPQLLGEIYAHKQNQWTHAQTFFFGIATKHVITLLKPCFGNISFKTIRQEIIRYLKSLSQPECNEKL-VHPKKLFFCLIENQEERFVSQVMNLFEEITVDISDSDDLGAAEYSLLRASKLKNLHLHIQKKVFSEIHDPEYGSLENFKLDQKFSAINWTMLSILFCNLHVLDLGSCHFNKKVIEVLCNSLSPTPNMPLTVFKLQRLLCSFMTNFGDGSLFCTFLQIPQLKYLNLYGTDLSNDVVEMLCSALKCSTCRVEELL-------------------LGKCDISSEACGIMATFLIN-SKVKHLSLVENPLKNKGVMFLCKMLKDPSCVLESLMLSYCCLTFIACGHLYEALLSNKHLSLLDLGSNFLEDIGVNLLCEALKYPNCTLKELWLPGCYLTSECCEEISAVLTCNKNLKTLKLGNNNIQDTGVKRLCEALCHPKCKVQCLGLDMCELSNDCCEDLALALITCNTLKSLNLDWNALHHSGLVMLCEALNHKKCKLNMLGLDKSSFSEESQTFLQAVEKKNNNLNVLHFPWVEDELKKRGVRLVWNSKN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7RTR0-1", "uniprot_id": "NLRP9_HUMAN", "id": "Q7RTR0-1", "name": "NACHT, LRR and PYD domains-containing protein 9", "aln": "MAESFFSDFGLLWYLKELRKEEFWKFKELLKQPLEKFELKPIPWAELKKASKEDVAKLLDKHYPGKQAWEVTLNLFLQINRKDLWTKAQEEMRNKLNPYRKHMKETFQLIWEKETCLHVPEHFYKETMKNEYKELNDAYTAAARRHTVVLEGPDGIGKTTLLRKVMLDWAEGNLWKDRFTFVFFLNVCEMNGIAETSLLELLSRDWPESSEKIEDIFSQPERILFIMDGFEQLKFNLQLKADLSDDWRQRQPMPIILSSLLQKKMLPESSLLIALGKLAMQKHYFMLRHPKLIKLLGFSESEKKSYFSYFFGEKSKALKVFNFVRDNGPLFILCHNPFTCWLVCTCVKQRLERGEDLEINSQNTTYLYASFLTTVFKAGSQSFPPKVNRARLKSLCALAAEGIWTYTFVFSHGDLRRNGLSESEGVMWVGMRLLQRRGDCFAFMHLCIQEFCAAMFYLLKRPKDDPNPAIGSITQLVRASVVQPQTLLTQVGIFMFGISTEEIVSMLETSFGFPLSKDLKQEITQCLESLSQCEADREA-IAFQELFIGLFETQEKEFVTKVMNFFEEVFIYIGNIEHLVIASFCLKHCQHLTTLRMCVEN-IFPDDSGCISDYNEKLVYWRELCSMFITN-----KNFQILDMENTSLDDPSLAILCKALAQP------VCKLRKLIFTSVYFGHDSELFKAVLHNPHLKLLSLYGTSLSQSDIRHLCETLKHPMCKIEELI-------------------LGKCDISSEVCEDIASVLACNSKLKHLSLVENPLRDEGMTLLCEALKHSHCALERLMLMYCCLTSVSCDSISEVLLCSKSLSLLDLGSNALEDNGVASLCAALKHPGCSIRELWLMGCFLTSDSCKDIAAVLICNGKLKTLKLGHNEIGDTGVRQLCAALQHPHCKLECLGLQTCPITRACCDDIAAALIACKTLRSLNLDWIALDADAVVVLCEALSHPDCALQMLGLHKSGFDEETQKILMSVEEKIPHLTISHGPWIDEEYKIRGVLL------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : *.:*** :::* . ** *** *:: ***:***:.* :::::***.:. * .*** :.*:: *.****:**:** ** : * * . *::.** *: ** *: :*:: *: :. :*: * : : . : *.:: *. * ***.:***.*****. * ::** :**.:.* .:*. :* ** **:* **.**.::**:*:*::***::***: ***:*:*:::*.:***: * :******* *** .***: **. : : :*: *: * : *:** * ** : .::: : ::. :: ** * *:.*: : * ... :.: *: :.**: ..* :* ::::**:**.**:*. :**. ***** :***: :*: *::** :.. * * :* : * :**:* : ** *.**.:.**: .: :. : ::**: .:.: ::*:. ** ::**: ::.*.* *. .: : ** : :.:*:.** :::: :**: : * . . : * :. ::..*:: ::: :* : . :. : *. ** :.*: *:** :.**** ** . . ** :*: . * :***: ****.***:.* :* * *::**********:::*: **: **.. *.*: *** ***** ::*. : *.*:..: ********* *** ** ** *** *.* ::**** **:***:.*::*:*** ** :*******:*:* ****::** ** **:*:::****: * :: **.*:* .* :*:**.****** ::. ..: **:**.* * *::***.** *. *:*.:* **:* :*.: * **.. * : **. * ", "identical_positions": 355, "similar_positions": 301, "identity": "34.5%" }, { "cls_id": "homologset.agr.RGD:1308982", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZTN0-1", "uniprot_id": "D3ZTN0_RAT", "id": "D3ZTN0-1", "name": "DNA-dependent protein kinase catalytic subunit", "aln": "MADPGAGLRCWLLQLQEFVSAADRYNAAGASYQLIRGLGQECVLSTCSAVQALQISLVFSKEFGLLVFIRKSLSIDEFRDCREEALKFLCVFLEKIDQKVLHYSFDIKNTCISVYTKDRTAKCKIPALDLLIKLLKILRSSRVMDEFKIGELFNKFYGELVSKSKLPDTVLEKVYELLGVLGEVHPSEMVNHSENLFRAFLGELKTQMTSTVREPKFPVLAGCLKGLSSLLCNFTKSMEEDPQTSKEIFGFTLKAIRPQIEMKRYAVPLAGLRLLTLHASQFTTCLLDNYITLFEVLSKWCNHTNVELKKAAHSALESFLKQISFTVAEDAELHKSKLKYFMEQFYGIIRNADSNNKDLAIAIRGYGLFAGPCKVINAKDVDFMYVELIQRCKQMFLTQTDATEDHVYQMPSFLQSIASVLLYLDTVPEVYTPVLEHLMVVQIDSFPQYSPKMQLVCCKALVKVFLSLTEKGPVHWNCISAVVHQGLIRICSKPVVLQKDVESRSENRWASEEVRMGRWKVPTYKDYVDLFQNLLGCDQMADFILGDETFLFVNSSLKSLNHLLYDEFIRSVLKIVEKLDLTLEKQTTGEQEDERTAD-VWVIPTSDPAANLHPIKPNDFSAFINLVEFCREILPKKQVSFFEPWVYSFAYELILQSTRLPLISGFYKLLSIAVKNARKIKYFEGVSPKCLKHSPENTEKHSCFALFAKFGKEVSVKMKQYKDELLASCLTFVLSLPPDIIKLDVRAYVPALQMAFKLGLSHLPLAEIGLHALKEWSVHIDKSIMQPYYKDIVPCLDGYLNTSTLSDETKSHWEVSALSRAARKGFNRDVVKLLKRTRNVTSDEALSLEEIRIRVVQILGSLGGQINKNLITATSG-ERMKKYVAWDREKRLSFAVPFREMKPVIYLDVFLPRVTELALSASDRQTKVAACELLHSMVMFMLGRATQMPEG-QGLPPMYQLYKHMFPVLLKLACDVDQVTRQLYEPLVMQLIHWFTNNKKFESQDTVALLEAILDGIVDPVDSTLRDFCGQCVQEFLKWSIKQTTPQQQEKSPVNSKSLFKRLYSLALHPNAFKRLGAALAFNHIYKEFREEGSLVEQFVFEALVTYMESLALAHADEKSLGTIQQCCDAIDHLRRIIEKKYISLNKAKKRRLPRGFPPLTSLCLLDLVKWLFAHCGRPQTECRHKSIELFYKFVPLLPGNKSPSLWLRDLIKAEGISFLINTFEGGASSSGQPSGILAQPTLLHLQGPVSLRGMLQWLDHLLAALECYNTFIEEKTVQVQEVLGTEVQSSLLKSVAFFLESIATCDARTVEQRFGTGLTG-PPSVQEEEKYNYSKCTVLVRIMEFTTTLLVTFPEDCKLLEKDLCNTKLMKVLVKMLCEPLSIGFNIGDVQVMNHLPSICVNLLKALRKSPYRDKLETHLKEKVTAQSVEELCAINLCSSAACQERTKLLSLLSACKQLHKAGFSHIISASQSTALNHSIGMRLLSLVYNGIAPAQEKQYLQSLDPSCKSLASGLLELAFAFGGLCEHLVSLLLNSSMLSTQYLGSSQ-RNISFSHGEYFYSLFPEVINTELLKSLDVTVSRLLESSSDNPKMVSTILNGMLDMSFRDRAVQKHQGLKLATAILQNWRKCDSWWAPDSAPESKTTVLSLLAKMLQIDSTLSFDTNHSSFSEIFTTYANLLADTKLGLHLKGQAVILLPFFTRVTEDRLGDLKHILEKFIVLNFPMKSDEFPPDSLKYNNYVDCMKKFLDALELSQSPMLLQLMTDILCREQQHIMEELFQTTFKRIARRSPCVTQLNLLESVYTMFRKGGLLSDVT-QAFVDRSLLTLLWHCDLDTLKEFFSRIVVEAIDVLKSRFTKLND-TFDTQITKKMCYYKMLAVMYSRLLKDDVHSKESKINQAFQGSCVAEGNELTKTLLKLCHDAFTENMAGESQLLEKRRLYHCAAYNCAISLISRVFNELKFYQGFLFSEKPEKNLFIFENLIDLKRCYTFPIEVEVPMERKKKYVEIRKEARDAANGASGNPRYMSSLSYLTESSLSEEMSQFDFSTGVQSYSYSSQDRKPTTGHFQRREHQDSMAQDDIIELEMDELNQHECMAPMTSLIKHMQRNVIAPKGQEGSISKDLPPWMKFLHDKLENASVSLNIRLFLAKLVINTEEVFRPYAKHWLGPLLQLAVCENIG-EGIHYMIVEIVATILSWTGLATPTGVPKYEVLANRLLYFLMKYVFHPKRAVFRHNLEIIKTLVECWKECLSIPYRLIFEKFSNKDPNSKDNSVGIQLLGIVVANNLPPYDLKGDITSAMYFEALVNNMSFVKYKEVYAAAAEVLGLILQHVTERKHVIAESVYELVVKQLKQHQNTMEDKFIVCLNKIVKGFPPLADRFLNALFFLLPKFHGVMKTLCLEVVLCRAEAITGLYLQLKSKDFLQVMRHRDDERQKVCLDIIYKMVAKLKPTELRELLNPVVEFVSHPSPTCREQMYNILMWIHDNYRDPESQMDEDSQEIFKLAKDVLIQGLIDENLGLQLIIRNFWSHETRLPSNTLDRLLALNSLYSPKIEVHFLSLATNFLLEMTRMSPDYLNPIFEHPLSECEFQEYTIDPDWRFRSTVLTPMFIETQAFPSTLNTQTQEGSPSDRRQKPGQVRATQQQYDFTPTQTSVERSSFDWLTGSSIDLMADHTVFSSESLSSSLLFSHKKSEKSQRVSWKSVGPDFGTKKLGLPGDEVDNQVKSGTHSQTEILRLRRRFLKDQEKLSLLYAKRGLMEQKLEKDIKSELKMKQDAQVVLYRSYRHGDLPDIQIQHSSLITPLQAVAQKDPIIAKQLFSSLFSGILKEMHKFRTTSEKNIIIQNLLQDFNRFLNTTFLFFPPFVSCIQEISCQHVDLLTLDPAAVRVGCLASLQQPGGIRLLEEALLHLLPKEPPTKRIRGKTCLPPDVLRWMELAKLYRSIGEYDVLHGIFSSELGTKQDTQNALLAEARSDYFQAANLYKEALNKLEWLDGEPTEAEKEFWEMASLDCYNNLSQWKELEYRSTVNIGSENSLDLSKMWSKPFYQETYLPYVIRSKLKLLLQGEDNQSLLTFVDEAMHKELQQMVLELQYSQELSLLYILQDDIDRATYYIKNAIQIFMQNYSSIDVLLYRSRLAKLQSVQTLAEIEEFLNFIRKHGDLSSLGPLRRLLKTWTSRYPDTVTDPMHIWDDIITNRCFFLSKIEERLTVSPGDHSMSVDEDEDSFAR-EGSEPKEDAHHILQSCRFTMKMKMIESSWKQNNFSLSMKLLKEMHKESKIRESWRMQWIHSFCQLNHCRSHTQSPQEQVLTMLKTITLLDESDISNYLNKNIQAFCDQNILLGTSCRIMADALSREPACLSGLEKSKTESIFALSGSNTENTERVISGLYQRAFHHLSMAVQSAEEETQLSCWGHEAAAERAHAYMTLVGFCDQQLRKVEESASTASQKISTELEGYPALVVEKMLRALKLNSSEARLKFPRLLQIIEQYPEETVNIIIKEISSIPCWQFIGWIGHMVALLDKEEAIAVQHTVEEIADNYPQAIIYPFIISSESYSFQNTSSGHNNKAFVERIKSKLDQGGVIQGFINALDQLSNPDMLFKDWVNDTKDELGKNPVNKKNIEKLYERMYAALGDFRAPGLGPFRRKFIQTFGKEFVKSFGNGGSKLLTMKLDEFRNITDSLFVRMRKDSKLPGNLKEYSPWMSEFT---VKSELEIPGQYDGKSKPLPEYHVRISGFDERVKVMVSLRKPKRIVIRGHDEKEYPFLVKGGEDLRQDQRIEQLFEVMNAILSQDAACSQRNMQLRTYRVVPMTSRLGLIEWIENTMTLKDLLLSNMSQEEKVAYDSDSKAPIYDYRDWLIKVSGRSDVKGYTLMYSRANRTETVTAFRRRENKVPADLLKRAFVKMSTSPEAFLALRSHFASSHALLCISHWLLGIGDRHLNNFMVAMETGSVIGIDFGHAFGSATQFLPIPELMPFRLTRQFISLMLPMKETGLVCTVMVHALRAFRSCAGLLTDTMEVFVKEPSFDWKGFEQTMLRKGGSWIQEINVTEKNWYPQHKIRYAKRKLAGANPAVITCDELRLGHEASPAFRSYVAVARGNKDYNIRAQEPESRLSEETQVKCLVDQATDPNILGRTWEGWEPWM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97313-1", "uniprot_id": "PRKDC_MOUSE", "id": "P97313-1", "name": "DNA-dependent protein kinase catalytic subunit", "aln": "MAEEGTGVRCWLLQLQEFLSAADRCSAAGASYQLIRSLGQECVLSTSSAVQALQISLVFSRDFGLLVFIRKSLSIEDFRDCREEALKFLCVFLEKIDQKVMHYSLDIKNTCTSVYTKDRTAKCKIPALDLLIKLLQILRSTRLMDEFKIGELFNKFYGELASKSKLPDTVLEKVYELLGVLGEVHPSEMINHSENLFRAFLGELKTQMTSTVREPKFPVLAGCLKGLSSLLCNFTKSMEEDPQTSKEIFGFTFKAIRPQIEMKRYAVPLAGLRLLTLHASQFTACLLDNYITLFEVLSKWCSHTNVELKKAAHSALESFLRQISFTVAEDAELHKSRLKYFMEQFYGIIRNTDSNNKELAIAIRGYGLFAGPCKVINAKDVDFMYVELIQRCKQMFLTHADASEDHVYQMPSFLQSIASVLLYLDTVPEVYTPVLEHLMVVQIDSFPQYSPKMQLVCCKAIIKLFLALSEKGPVHWNCISAVVHQGLIRICSKPVVLQKDVESRSDNRSASEEVRTGRWKVPTYKDYVDLFQHLLGCDQMEDFILGDETFLFVNSSLKSLNHLLYDEFIRSVLKIVEKLDLTLEKQTVGEQEDGSTAD-VWVIPTSDPAANLHPAKPSDFSALINLVEFCREILPRKHVGFFEPWVYSFAYELILQSTRLPLISGFYKLLSIAVKNARKIKYFEGISPKSLKHSPEDTEKYSCFALFAKFGKEVSVKMKQYKDELLASCLTFVLSLPHDIIELDVRAYVPALQMAFKLGLSHMPLAEIGLHALKEWSVHIDKSILQPYYKDILPCLDGYLNTSTLSDETKSHWGLSALSRAAQKGFNRHVVKHLKRTRNSSPDEALSLEEIRIKVVQILGSLGGQINKSLVTATSG-ERMKKYVAWDAERRLSFAVPFREMKPVIYLDVFLPRVTELALSASDRQTKVAACELLHSMVMFMLGRATQMPEG-QGLPPMYQLYKHTFPVLLQLACDVDQVTRQLYEPLVMQLIHWLTNNKKFESQDTVALLEAILDGIVDPVDSTLRDFCGRCVQEFLKWSIKQTTPQQQEKSPVNSKSLFKRLYSLALHPNAFKRLGAALAFNHIYKEFREEGSLVEQFVFEALVTYMESLALAHEDEKSLGTVQQCCDAIDHLRRIIEKKHVSLNKAKKRRLPQGFPPLTSLCLLDLVEWLLAHCGRPQTECRHKSMELFYKFVPLLPGNKSPSLWLKDLIKKKGISFLINTFEGGASSSDQPAGILAQPTLVYLQGPISLRGVLQWLDLLLAALECYNTFIEKETVQGQEVLGAEVQSSLLKSVAFFLESIATHSARAVEQRFGSGAPG-PPSLHEEEKYNYSKCTVLVRIMEFTTTLLIASPEDCKLLEKDLCNTNLMQVLVKMICEPMSLGFNIGDVQVMNHLPSICVNLLKALRKSPYRDMLETHLKEKVTVQSVEELCSINLCSSGARQERSKLLSILSACKQLHKAGFSHVISPSQSTALNHSVGMRLLSLVYKGIVPAEERQCLQSLDPSCKSLANGLLELAFGFGGLCDHLVSLLLNSAMLSTQYLGSSQ-RNISFSHGEYFYSLFSEVINSELLKNLDIAVSRLMESSSDNPKMVSTVLNGMLDTSFRDRAVQKHQGLKLATAILQNWRKCDSWWAPDSAPESKTTVLSLLAKMLQIDSALSFDTNHSSFSEIFTTYASLLADTKLGLHLKGQAIILLPFFTSLREGSLENLKHILEKLIVCNFPMKSDEFPPDSLKYNNYVDCMKKFLDALELSQSPMLFQLMTDILCREQRHIMEELFQTTFKRIARQSPCVTQLNLLESVYTMFRKADLPSNVTRQAFVDRSLLTLLWHCDLDTLKEFFSRIVVDAIDVLKSRFTKLNEFTFDTQITKKMCYYKMLAVMYSRLLKDDVHSKEAKINQAFHGSRVAEGNELTKTLLKLCHDAFTENMVGESQLLEKRRLYHCAAYNCAISLISCVFNELKFYQGFLFNEKPEKNLFIFENLIDLKRCYTFPIEVEVPMERKKKYIEIRKEARDAANGASGSPHYMSSLSYLTDSSLSEEMSQFDFSTGVQSYSYSSQDRKPTTGHFQRREHQDSMTQDDIMELEMDELNQHECMAPMIALIKHMQRNVIAPKGEEGSIPKDLPPWMKFLHDKLGNASVSLNIRLFLAKLVINTEEVFRPYAKHWLSPLLQLAVCENNR-EGIHYMMVEIVATILSWTGLATPTGVPKDEVLANRLLRFLMKHVFHPKRAVFRHNLEIIKTLVECWKECLSIPYRLIFEKFSHKDPNSKDNSVGIQLLGIVIANNLPPYDPNCDITSAMYFEALVNNMSFVKYKEVYAAAAEVLGLILQYITERKHVIAELVCELVIKQLKQHQNTMEDKFIVCLNKIAKGFPPLADRFLNALFFLLPKFHGVMKTLCLEVVLCRAEEITGLYLQLKSKDFLQVMRHRDDERQKVCLDIVYKMVAKLKPIELRELLNPVVEFVSHPSPTCREQMYNILMWIHDNYRDQESQNDEDSQEIFKLAKDVLIQGLIDENVGLQLIIRNFWSHETRLPSNTLDRLLALNSLYSPKIEVHFLSLATNFLLEMTRMSPDYLNPIFEHPLSECEFQEYTIDPDWRFRSTVLTPMFIETQASPSILHTQTQEGPLSDQRQKPGQVRATQQQYDFTPTQASVERSSFDWLTGSSIDLLADHTVFSSETLSSSLLFSHKRTEKSQRMSCKSVGPDFGTKKLGLPDDEVDNQVKSGTPSQADILRLRRRFLKDREKLSLLYAKRGLMEQKLEKDIKSEFKMKQDAQVVLYRSYRHGDLPDIQIQHSGLITPLQAVAQKDPIIAKQLFSSLFSGILKEMNKFKTTSEKNIITQNLLQDFNRFLNTTFLFFPPFVSCIQEISCQHPDFLTLDPASVRVGCLASLQQPGGIRLLEEALLRLMPKEPPTKRVRGKTCLPPDVLRWMELAKLYRSIGEYDVLRGIFSSELGTTQDTQNALLAEARSDYCQAAKLYDEALNKLEWVDGEPTEAEKEFWELASLDCYNNLSKWKELEYCSTVNIVSENSLDLSKMWSEPFYQETYLPYVIRSKLKLLLQGEGNQSLLTFVDEAMNKELQKTVLELQYSQELSLLYILQDDIDRATYYIKNGIQIFMQNYSSIDVLLYRSRLAKLQSVQTLAEIEEFLSFICKHGDLSSLGPLRRLLKTWTSRYPDVVTDPMHIWDDIITNRCFFLSKIEERLTAPSGDHSMSVDEDEESIDR-EVYEPKEDVRCMLQSCRFTMKMKMIESAWKQSNFSLSMKLLKEMHKESKTREIWRVQWLHSYSQLNHCRSHTQSPREQVLNMLKTITLLDESDISNYLNKNIQASCDQSILLGTTCRIMADALSREPACLSDLEENKVNSILTLSGSNAENTETVITGLYQRAFHHLSKAVQSAEEETQLSCWGHEAAAERAHAYMTLVGFCDQQLRKVEESAS---QKTSAEMEAYPALVVEKMLRALKLNSSEARLKFPRLLQIIEQYSEETLNIMTKEISSIPCWQFIGWISHMMALLDKEEAIAVQHTVEEIADNYPQAIIYPFIISSESYSFKNTSSGHNNKAFVERIKSKLDHGEVIHSFINALDQLSNPDLLFKDWVSDTKDELGKNPVNKKNIEKLYERMYAALGDLRAPGLGPFRRRFIQAFGKEFVKSFGNGGSKLLTMKVDDFCKITGSLLVRMKKDSKLPGNLKEYSPWMSEFKAQFLKNELEIPGQYDGKSKPLPEYHVRISGFDERVKVMLSLRKPKRIVIRGHDEKEYPFLVKGGEDLRQDQRIEQIFEVMNAILSQDAACSQRNMQLRTYRVVPMTSRLGLIEWIENTMTLKDLLLSNMSQEEKVANNSDPKAPIRDYKDWLMKVSGKSDAGAYVLMYSRANRTETVVAFRRRESQVPPDLLKRAFVKMSTSPEAFLALRSHFASSHALLCISHWLLGIGDRHLNNFMVAMETGSVIGIDFGHAFGSATQFLPVPELMPFRLTRQFVSLMLPMKETGLMCTVMVHALRAFRSCAGLLTDTMEIFVKEPSFDWKSFEQTMLRKGGSWIQEINVTEKNWYPQHKIRYAKRKLAGANPAVITCDELYLGHEASSAFRSYTAVARGNRDYNIRAQEPESGLSEETQVKCLVDQATDPNILGRTWEGWEPWM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P78527-1", "uniprot_id": "PRKDC_HUMAN", "id": "P78527-1", "name": "DNA-dependent protein kinase catalytic subunit", "aln": "MAGSGAGVRCSLLRLQETLSAADRCGAALAGHQLIRGLGQECVLSSSPAVLALQTSLVFSRDFGLLVFVRKSLNSIEFRECREEILKFLCIFLEKMGQKIAPYSVEIKNTCTSVYTKDRAAKCKIPALDLLIKLLQTFRSSRLMDEFKIGELFSKFYGELALKKKIPDTVLEKVYELLGLLGEVHPSEMINNAENLFRAFLGELKTQMTSAVREPKLPVLAGCLKGLSSLLCNFTKSMEEDPQTSREIFNFVLKAIRPQIDLKRYAVPSAGLRLFALHASQFSTCLLDNYVSLFEVLLKWCAHTNVELKKAALSALESFLKQVSNMVAKNAEMHKNKLQYFMEQFYGIIRNVDSNNKELSIAIRGYGLFAGPCKVINAKDVDFMYVELIQRCKQMFLTQTDTGDDRVYQMPSFLQSVASVLLYLDTVPEVYTPVLEHLVVMQIDSFPQYSPKMQLVCCRAIVKVFLALAAKGPVLRNCISTVVHQGLIRICSKPVVLPKGPESESEDHRASGEVRTGKWKVPTYKDYVDLFRHLLSSDQMMDSILADEAFFSVNSSSESLNHLLYDEFVKSVLKIVEKLDLTLEIQTVGEQENGDEAPGVWMIPTSDPAANLHPAKPKDFSAFINLVEFCREILPEKQAEFFEPWVYSFSYELILQSTRLPLISGFYKLLSITVRNAKKIKYFEGVSPKSLKHSPEDPEKYSCFALFVKFGKEVAVKMKQYKDELLASCLTFLLSLPHNIIELDVRAYVPALQMAFKLGLSYTPLAEVGLNALEEWSIYIDRHVMQPYYKDILPCLDGYLKTSALSDETKNNWEVSALSRAAQKGFNKVVLKHLKKTKNLSSNEAISLEEIRIRVVQMLGSLGGQINKNLLTVTSSDEMMKSYVAWDREKRLSFAVPFREMKPVIFLDVFLPRVTELALTASDRQTKVAACELLHSMVMFMLGKATQMPEGGQGAPPMYQLYKRTFPVLLRLACDVDQVTRQLYEPLVMQLIHWFTNNKKFESQDTVALLEAILDGIVDPVDSTLRDFCGRCIREFLKWSIKQITPQQQEKSPVNTKSLFKRLYSLALHPNAFKRLGASLAFNNIYREFREEESLVEQFVFEALVIYMESLALAHADEKSLGTIQQCCDAIDHLCRIIEKKHVSLNKAKKRRLPRGFPPSASLCLLDLVKWLLAHCGRPQTECRHKSIELFYKFVPLLPGNRSPNLWLKDVLKEEGVSFLINTFEGGG--CGQPSGILAQPTLLYLRGPFSLQATLCWLDLLLAALECYNTFIGERTVGALQVLGTEAQSSLLKAVAFFLESIAMHDIIAAEKCFGTGAAGNRTSPQEGERYNYSKCTVVVRIMEFTTTLLNTSPEGWKLLKKDLCNTHLMRVLVQTLCEPASIGFNIGDVQVMAHLPDVCVNLMKALKMSPYKDILETHLREKITAQSIEELCAVNLYGPDAQVDRSRLAAVVSACKQLHRAGLLHNILPSQSTDLHHSVGTELLSLVYKGIAPGDERQCLPSLDLSCKQLASGLLELAFAFGGLCERLVSLLLNPAVLSTASLGSSQGSVIHFSHGEYFYSLFSETINTELLKNLDLAVLELMQSSVDNTKMVSAVLNGMLDQSFRERANQKHQGLKLATTILQHWKKCDSWWAKDSPLETKMAVLALLAKILQIDSSVSFNTSHGSFPEVFTTYISLLADTKLDLHLKGQAVTLLPFFTSLTGGSLEELRRVLEQLIVAHFPMQSREFPPGTPRFNNYVDCMKKFLDALELSQSPMLLELMTEVLCREQQHVMEELFQSSFRRIARRGSCVTQVGLLESVYEMFRKDDPRLSFTRQSFVDRSLLTLLWHCSLDALREFFSTIVVDAIDVLKSRFTKLNESTFDTQITKKMGYYKILDVMYSRLPKDDVHAKESKINQVFHGSCITEGNELTKTLIKLCYDAFTENMAGENQLLERRRLYHCAAYNCAISVICCVFNELKFYQGFLFSEKPEKNLLIFENLIDLKRRYNFPVEVEVPMERKKKYIEIRKEAREAANGDSDGPSYMSSLSYLADSTLSEEMSQFDFSTGVQSYSYSSQDPRPATGRFRRREQRDPTVHDDVLELEMDELNRHECMAPLTALVKHMHRSLGPPQGEEDSVPRDLPSWMKFLHGKLGNPIVPLNIRLFLAKLVINTEEVFRPYAKHWLSPLLQLAASENNGGEGIHYMVVEIVATILSWTGLATPTGVPKDEVLANRLLNFLMKHVFHPKRAVFRHNLEIIKTLVECWKDCLSIPYRLIFEKFSGKDPNSKDNSVGIQLLGIVMANDLPPYDPQCGIQSSEYFQALVNNMSFVRYKEVYAAAAEVLGLILRYVMERKNILEESLCELVAKQLKQHQNTMEDKFIVCLNKVTKSFPPLADRFMNAVFFLLPKFHGVLKTLCLEVVLCRVEGMTELYFQLKSKDFVQVMRHRDDERQKVCLDIIYKMMPKLKPVELRELLNPVVEFVSHPSTTCREQMYNILMWIHDNYRDPESETDNDSQEIFKLAKDVLIQGLIDENPGLQLIIRNFWSHETRLPSNTLDRLLALNSLYSPKIEVHFLSLATNFLLEMTSMSPDYPNPMFEHPLSECEFQEYTIDSDWRFRSTVLTPMFVETQASQGTLQTRTQEGSLSARWPVAGQIRATQQQHDFTLTQTADGRSSFDWLTGSSTDPLVDHTSPSSD----SLLFAHKRSERLQRAPLKSVGPDFGKKRLGLPGDEVDNKVKG-AAGRTDLLRLRRRFMRDQEKLSLMYARKGVAEQKREKEIKSELKMKQDAQVVLYRSYRHGDLPDIQIKHSSLITPLQAVAQRDPIIAKQLFSSLFSGILKEMDKFKTLSEKNNITQKLLQDFNRFLNTTFSFFPPFVSCIQDISCQHAALLSLDPAAVSAGCLASLQQPVGIRLLEEALLRLLPAELPAKRVRGKARLPPDVLRWVELAKLYRSIGEYDVLRGIFTSEIGTKQITQSALLAEARSDYSEAAKQYDEALNKQDWVDGEPTEAEKDFWELASLDCYNHLAEWKSLEYCSTASIDSENPPDLNKIWSEPFYQETYLPYMIRSKLKLLLQGEADQSLLTFIDKAMHGELQKAILELHYSQELSLLYLLQDDVDRAKYYIQNGIQSFMQNYSSIDVLLHQSRLTKLQSVQALTEIQEFISFISKQGNLSSQVPLKRLLNTWTNRYPDAKMDPMNIWDDIITNRCFFLSKIEEKLTPLPEDNSMNVDQDGDPSDRMEVQEQEEDISSLIRSCKFSMKMKMIDSARKQNNFSLAMKLLKELHKESKTRDDWLVSWVQSYCRLSHCRSRSQGCSEQVLTVLKTVSLLDENNVSSYLSKNILAFRDQNILLGTTYRIIANALSSEPACLAEIEEDKARRILELSGSSSEDSEKVIAGLYQRAFQHLSEAVQAAEEEAQPPSWSCGPAAGVIDAYMTLADFCDQQLRKEEENAS---VIDSAELQAYPALVVEKMLKALKLNSNEARLKFPRLLQIIERYPEETLSLMTKEISSVPCWQFISWISHMVALLDKDQAVAVQHSVEEITDNYPQAIVYPFIISSESYSFKDTSTGHKNKEFVARIKSKLDQGGVIQDFINALDQLSNPELLFKDWSNDVRAELAKTPVNKKNIEKMYERMYAALGDPKAPGLGAFRRKFIQTFGKEFDKHFGKGGSKLLRMKLSDFNDITNMLLLKMNKDSKPPGNLKECSPWMSDFKVEFLRNELEIPGQYDGRGKPLPEYHVRIAGFDERVTVMASLRRPKRIIIRGHDEREHPFLVKGGEDLRQDQRVEQLFQVMNGILAQDSACSQRALQLRTYSVVPMTSRLGLIEWLENTVTLKDLLLNTMSQEEKAAYLSDPRAPPCEYKDWLTKMSGKHDVGAYMLMYKGANRTETVTSFRKRESKVPADLLKRAFVRMSTSPEAFLALRSHFASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSATQFLPVPELMPFRLTRQFINLMLPMKETGLMYSIMVHALRAFRSDPGLLTNTMDVFVKEPSFDWKNFEQKMLKKGGSWIQEINVAEKNWYPRQKICYAKRKLAGANPAVITCDELLLGHEKAPAFRDYVAVARGSKDHNIRAQEPESGLSEETQVKCLMDQATDPNILGRTWEGWEPWM", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** *:*:** **:*** :***** .** *.:****.********:..** *** *****::******:****. :**:**** *****:****:.**: **.:***** *******:***************: :**:*:**********.******. *.*:*************:*********:*::*****************:*****:****************************:***.*.:*******::****** *****::******::******::***** *** ********** *******:*:* **::**:**.:*:************.*****:*:**************************************::*: :*:**********:*********************:*:*****************:*::*:**:*: **** ****:**************** *. **.*::: ** *** *:*************::**..*** * **.**:*: **** :**********::************** **.****: * **:************ **.****:************.*:. *********:**********************:*:**:*******:***.******:.**:******.******:*****************:**** :**:*******************: ****:**:**:***::**: ::*******:*******:**:******.:* :*******:****: *:* **:*:* :.:**:*******:***:**********.*:*.**. * **.***** *:***************:*************:***********************:******* ** ********: *****:***********************:***********************************:*::********* ***********:**********************:****:**:***** ************ ********* *******:********** ******::***********:**** :********:**:**************:*************:**.***:*::* :*:**********. ..**:********::*:**.**:. * *** ************ :.** :***:*.******:********* . :.*: **:* .* .* :* *:********:*********** : **. ***:******:**:***: :*** *:********** ***.:****:***: ***:* *****:**:*.**:****::** .. * :*::* :::*******:**: * * .**** *:**:* .******:**.*.:*:* * *** ***.**.*******.*****::*******.::*** ***** * ***********.*.**:****.**::* .*::** **.****::****** ***:** **********:***:*:******* **. *:* :**:****:*****::**:*.*.**.*:**** .*******.*******: ****** : . * :*:::**::** :***:* ****.: ::**********************::***::*****:*:******::*:****:..****:.****** **** . ..* *:*************.**:*:**** ***:*************: ********** ***:* ****** *****:**:****.*:** ::*********:***:*******.**.****:**************:*. *************.*******:********** *.**:************:*******:**** *..* ********::*:*********************** :*:**:*:***::*. .:**::********:******: :*:***:*.: .*:*:*.*:.:***.******.** *. *.**************************.******..** ******:********************* ******** ****:************************:************** ******************:**:***** : .* *: **:*********:****************::: ***::: * : *** ********************:.*.********:**:**********:***********.* :* **:*******:*****************:***:.**** *****************.******************* **: *:********************* *************************************************** ***** **:****************.*************:**** . *:*:****. * : .**:******:*** **:: *********** * :.*** **: ****:**::*: ** . ********.*:****.*****:**. : .::::*******::*:*****:**::*: *** **:****:************************:**.**********:********************.**:* **** * *:************* **********:***** :*:****:* .********* **********:*:* * *:**:***: ********:***************:***:**:**.* **.********** :**: *.***** :*:*********:***:*******:*::**.*** **..* ***. **.*:**:**********:************ :******:*:**: ***: :***:*********:****:***.***:*.** ************::***:******:*:**:**:.** *:*:*** **:***:***.****. ***:******************:** . *:**.**:* :. * * * :** :::**:*:******:*: **.****:******:***** *: * :.*::*:.:*.****::*. ****.:***::****.::*.**.*** * **.*****: **:*:*** *****: :*:.*.. *: ****.:*::* **:*******:*** ***:****:* ..*. .** .*****..******** **.** *:*::.**********:******.**************:*.***:.:: *****:******.**.**:*****::*:****:****:*******:************::**:**:** ** *******:* **:.***********::***** .*.: **.*.*********:********** :*****.***:***:***** * **:****** **:.:* .**. *:::*.**** ****** *****:*. ::.**********:.**********:******.** ***:****:******:*:***************:**:*:***.**:**:***** :***** *************:***:*******..******.* **.:** :*:*** *:**: *. .* ***. *******.:**:**.:**.********:*********************:*****:******************.******************:************:.**********: ::********** .****:**::**********.***.**:***********:******::** ******************* **** :.***.*.*****.:*:********* **********:********************", "identical_positions": 3140, "similar_positions": 697, "identity": "75.88%" }, { "cls_id": "homologset.agr.RGD:1308983", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4A3X9-1", "uniprot_id": "D4A3X9_RAT", "id": "D4A3X9-1", "name": "Zinc finger protein with KRAB and SCAN domains 8", "aln": "MATESRKPSSAPSPPDQAPEEDLVIVKIEEDHGWDEESSVHENNIPGQELFRLRFRQLCYQETLGPREVLIQLRALCHQWLRPDLNSKEQILELLVLEQFLTILPKELQTLVKEHQLDNGEEVVTLLEDLERQINVLGQPVSAHTHGHRVLWDEVIPSKSASEPPSIHVQPMATMPKSPVPQKPHDRGERPDFTYKAMSSSQKPTPSQKGSSGDQEVTARLLTAGFQAPNEGLVLFQTLEKIEDMAVSLIREEWLLDPSQKDLNRDNRPEKYRNMFSLDGETRNENKELFSKQVISPRIQPHGEATAKCNGDIIVGLEHGETQDLLGKLERHQGNHTQEKRHKCDECGKSFAQNSGLVRHWRIHTGEKPYQCNVCSKAFSYRSALLSHQDIHNKVKRYHCKECGKAFSQNTGLILHQRIHTGEKPYQCNQCGKAFSQSAGLILHQRIHSGERPYECNECGKAFSHSSHLIGHQRIHTGEKPYECDECGKTFRRSSHLIGHQRSHTGEKPYKCNECGRAFSQKSGLIEHQRIHTGERPYKCKECGKAFNGNTGLIQHLRIHTGEKPYKCNECGKAFIQRSSLIRHQRIHSAEKPETTGV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q15776-1", "uniprot_id": "ZKSC8_HUMAN", "id": "Q15776-1", "name": "Zinc finger protein with KRAB and SCAN domains 8", "aln": "MAEESRKPS-APSPPDQTPEEDLVIVKVEEDHGWDQESSLHESNPLGQEVFRLRFRQLRYQETLGPREALIQLRALCHQWLRPDLNTKEQILELLVLEQFLTILPEELQTLVKEHQLENGEEVVTLLEDLERQIDILGRPVSARVHGHRVLWEEVVHSASAPEPPNTQLQSEATQHKSPVPQESQER---------AMSTSQSPTRSQKGSSGDQEMTATLLTAG----------FQTLEKIEDMAVSLIREEWLLDPSQKDLCRDNRPENFRNMFSLGGETRSENRELASKQVISTGIQPHGETAAKCNGDVIRGLEHEEARDLLGRLERQRGNPTQERRHKCDECGKSFAQSSGLVRHWRIHTGEKPYQCNVCGKAFSYRSALLSHQDIHNKVKRYHCKECGKAFSQNTGLILHQRIHTGEKPYQCNQCGKAFSQSAGLILHQRIHSGERPYECNECGKAFSHSSHLIGHQRIHTGEKPYECDECGKTFRRSSHLIGHQRSHTGEKPYKCNECGRAFSQKSGLIEHQRIHTGERPYKCKECGKAFNGNTGLIQHLRIHTGEKPYQCNECGKAFIQRSSLIRHQRIHSGEKSESISV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** ****** *******:*********:*******:***:**.* ***:******** *********.*****************:******************:***********:****************::**:****:.*******:**: * **.***. ::*. ** ******:.::* ***:**.** **********:** ***** **************************** ******::******.****.**:** ******. ******::******:* **** *::****:***::** ***:*************.*********************.**********************************************************************************************************************************************************************************************:**********************.**.*: .*", "identical_positions": 508, "similar_positions": 51, "identity": "84.95%" }, { "cls_id": "homologset.agr.RGD:1308984", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q3SWU4-1", "uniprot_id": "ZBT44_RAT", "id": "Q3SWU4-1", "name": "Zinc finger and BTB domain-containing protein 44", "aln": "MGVKTFTHSSSSHSQEMLGKLNMLRNDGHFCDITIRVQDRIFRAHKVVLAACSDFFRTKLVGQTEDE--------NKNVLDLHHVTVTGFIPLLEYAYTATLSINTENIIDVLAAASYMQMFSVASTCSEFMKSSILWN-------TPNSQPEKGLDAGQE---NSSNCNFTSRDG-SISPVSSECSAVERTIPVCRESRRKRKSYIVMSPESPVKCSTQTNSPQVLNSSASYAENRNQPVDSSLAFPWTFPFGIDRRIQPEKAKQAEN-TRTLELPGPSEAGRRMADYVTCESTK-------TTLPLGTEEDVRVKVERLSDEEVHEEVSQPVSASQSSLSDQQTVPGSEPVQEDLLISPQSSSIGSVDEGVTEGLPTLQSTSSTNAHADEDDRLENVQYPYQLYIAPSTSSTERPSPNGPDRPFQCPTCGVRFTRIQNLKQHMLIHSGIKPFQCDCCGKKFTRAYSLKMHRLKHEVIS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R0A2-1", "uniprot_id": "ZBT44_MOUSE", "id": "Q8R0A2-1", "name": "Zinc finger and BTB domain-containing protein 44", "aln": "MGVKTFTHSSSSHSQEMLGKLNMLRNDGHFCDITIRVQDKIFRAHKVVLAACSDFFRTKLVGQTEDE--------NKNVLDLHHVTVTGFIPLLEYAYTATLSINTENIIDVLAAASYMQMFSVASTCSEFMKSSILWN-------TPNSQPEKSLDAGQE---NSSNCNFTSRDG-SISPVSSECSAVERTIPVCRESRRKRKSYIVMSPESPVKCSTQTSSPQVLNSSASYAENRSQPVDSSLAFPWTFPFGIDRRIQPEKAKQAEN-TRTLELPGPSEAGRRVADYVTCESTK-------PTLPLGTEEDVRVKVERLSDEEVHEEVSQPVSASQSSLSDQQTVPGSEPVQEDLLISPQSSSIGSVDEGVTEGLPTLQSTSSTNAHADDDDRLENVQYPYQLYIAPSTSSTERPSPNGPDRPFQCPTCGVRFTRIQNLKQHMLIHSGIKPFQCDCCGKKFTRAYSLKMHRLKHEVIS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NCP5-1", "uniprot_id": "ZBT44_HUMAN", "id": "Q8NCP5-1", "name": "Zinc finger and BTB domain-containing protein 44", "aln": "MGVKTFTHSSSSHSQEMLGKLNMLRNDGHFCDITIRVQDKIFRAHKVVLAACSDFFRTKLVGQAEDE--------NKNVLDLHHVTVTGFIPLLEYAYTATLSINTENIIDVLAAASYMQMFSVASTCSEFMKSSILWN-------TPNSQPEKGLDAGQE---NNSNCNFTSRDG-SISPVSSECSVVERTIPVCRESRRKRKSYIVMSPESPVKCGTQTSSPQVLNSSASYSENRNQPVDSSLAFPWTFPFGIDRRIQPEKVKQAEN-TRTLELPGPSETGRRMADYVTCESTK-------TTLPLGTEEDVRVKVERLSDEEVHEEVSQPVSASQSSLSDQQTVPGSEQVQEDLLISPQSSSIGSVDEGVSEGLPTLQSTSSTNAPPDDDDRLENVQYPYQLYIAPSTSSTERPSPNGPDRPFQCPTCGVRFTRIQNLKQHMLIHSGIKPFQCDRCGKKFTRAYSLKMHRLKHEGKRCFRCQICSATFTSFGEYKHHMRVSRHIIRKPRIYECKTCGAMFTNSGNLIVHLRSLNHEASELANYFQSSDFLVPDYLNQEQEET----LVQYDLGEHGFESNSSVQMPVISQYHSKGKEP---------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BJS0-1", "uniprot_id": "A0A8M2BJS0_DANRE", "id": "A0A8M2BJS0-1", "name": "Zinc finger and BTB domain-containing protein 44", "aln": "MGVKTFTHNSPSHSQELLDKLNTLRSEGHFCDVTIRVQGQLFSAHKVVLACCSDFLRAKLSGKPAEEDPVIVGEDNKHVLDLQHVTVAGFAPLLEYAYTSTLSISTENIIDVLAAASYMQMFAVANTCSEFMKSSILWNAASSGAGAPGSIQPPGLHRPQEPPEGHASCTLAPVDALSPSPVSSECSVQERPIPVCRESRRKRKGFASPQPAS----STSPQVPNPSPSSSSFPESSAQALEPSLAFSWTYPFGVDRRFTPEKSKLPDGLLETSGASGQDSSGRALVEYLSCEGPRGLGVGGATGIEEEEEEDVQVKVERLSDEEVHEEASQPVSAPHSSLSDQQTVPGNEHNQEDLLISPQSSSIGSMDEGVTEGLQSMQGTPNTTGHMEEDERLENVQYPYHLYISPST----RPGLNGPERPFQCPTCGVRFTRIQNLKQHMLIHSGIKPFQCDRCGKKFTRAYSLKMHRLKHEGKRCFRCQICSATFTSFGEYKHHMRVSRHIIRKPRIYECKTCGAMFTNSGNLIVHLRSLNHEASELANYFQTSEFLLPDYLSHMQEEEGLGHFEISEQTFEASSSSSSVQTPVISQVSSTMNYDTHTSAPPSQTPNPRSGNGGEDAAGDLQKPTTAVTSLQDPEEDVGEKERGARKKKKRLVPITIE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "********.*.*****:*.*** **.:*****:*****.::* *******.****:*:** *:. :* **:****:****:** ********:****.*****************:**.************* :*.* .*. ** . :.*.::. *. * ********. **.************.: .* * .*... *: **:*:.*. *.::.****.**:***:***: *** * .:. .* .* ..:** :.:*::**..: . : ****:**************.******.:***********.* ***************:****:*** ::*.*..*.. ::*:*********:***:*** **. ***:********************************** ******************* ", "identical_positions": 300, "similar_positions": 96, "identity": "45.18%" }, { "cls_id": "homologset.agr.RGD:1308985", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CIA5-1", "uniprot_id": "S35B4_MOUSE", "id": "Q8CIA5-1", "name": "Nucleotide sugar transporter SLC35B4", "aln": "----MRPAFAVGLVFAGCCSNVIFLELLARTHPG-CGNIVTFAQFLFIAVEGFLFEANLGR-----KPPAIPIRYYAIMVTMFFTVSVVNNYALNLNIAMPLHMIFRSGSLIANMILGIIILKKRYSMFKYTSIALVSAGIFICTFMSAKQVTVQTGLS---DKDGFQAF-AWWLLGIAALTFALLMSARMGIFQETLYRQFGKHSKEALFYNHALPLPGFIFLASDIYDHVVLFNKSELYQVPVIGVT-----MPVMWFYLLMNVVTQYVCIRGVFILTTECTSLTVTLVVTLRKFVSLIFSILYFQNQFTMWHWLGTSFVFIGTLMYTEVWKNLGTTKSELQKDDKKD----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZAN4-1", "uniprot_id": "D3ZAN4_RAT", "id": "D3ZAN4-1", "name": "Solute carrier family 35 member B4", "aln": "----MRPAFAVGLVFAGCCSNVIFLELLARTHPG-CGNIVTFAQFLFIAVEGFLFEADLGR-----KPPAIPIRYYAIMVTMFFTVSVVNNYALNLNIAMPLHMIFRSGSLIANMILGIIILKKRYSMFKYTSIALVSAGIFICTFMSAKQVTVQSSLS---DKDGFQAF-AWWLLGIGALTFALLMSARMGIFQETLYRQFGKHSKEALFYNHALPLPGFIFLASDIYDHVVLFNKSELYQVPVLGVT-----VPIMWFYLLMNVVTQYVCIRGVFILTTECSSLTVTLVVTLRKFVSLIFSILYFQNQFTLWHWLGTVFVFTGTLMYTEVWKNLGATKSQLQKDDKKD----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q969S0-1", "uniprot_id": "S35B4_HUMAN", "id": "Q969S0-1", "name": "Nucleotide sugar transporter SLC35B4", "aln": "----MRPALAVGLVFAGCCSNVIFLELLARKHPG-CGNIVTFAQFLFIAVEGFLFEADLGR-----KPPAIPIRYYAIMVTMFFTVSVVNNYALNLNIAMPLHMIFRSGSLIANMILGIIILKKRYSIFKYTSIALVSVGIFICTFMSAKQVTSQSSLS---ENDGFQAF-VWWLLGIGALTFALLMSARMGIFQETLYKRFGKHSKEALFYNHALPLPGFVFLASDIYDHAVLFNKSELYEIPVIGVT-----LPIMWFYLLMNIITQYVCIRGVFILTTECASLTVTLVVTLRKFVSLIFSILYFQNPFTLWHWLGTLFVFIGTLMYTEVWNNLGTTKSEPQKDSKKN----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZW46-1", "uniprot_id": "S35B4_DANRE", "id": "Q7ZW46-1", "name": "UDP-xylose and UDP-N-acetylglucosamine transporter", "aln": "----MNTLFAVTLVFVGCCSNVVFLELLVRDFPG-CGNIVTFAQFAFIALEGFIFETNFGR-----KKPQIPLSNYVIMVTMFFTVSVINNYALDFNIAMPLHMIFRSGSLIANMILGIIILKNRYSMSKYLSIVLVSVGIFICTIMSAKQVNVEKGGT---EEDGVYAF-MHWLLGIAMLTFALLMSARMGIFQETLYKKYGKHSKEALFYNHCLPLPGFLLLSTNIYNHAVLFSQSPPMEVPVIGLS-----MPVMWFYLLMNVITQYVCIRGVFILTTECASLTVTLVVTLRKFLSLIISILYFQNPFTAWHWVGTAVVFLGTLLYTEVLSSIPAAFKGYKVDKKAE----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W429-1", "uniprot_id": "S35B4_DROME", "id": "Q9W429-1", "name": "Endoplasmic reticulum GDP-fucose transporter", "aln": "MALNLKALLGMLFVFIGCCSNVVFLELIIQIDPG-AGNLITFAQFLFIALEGLVFTSKFFT-----VRPKIALKDYVILVALFFGANVCNNYAFNFNIPMPLHMIFRSGSLMANMIMGIVLLKKRYNLRQYSSVAMITAGIILCTLVSSGDVKDNTHHSLKVDT-SYSDF-FWWTVGIGLLTIALLVTAYMGIYQEVIYKKYGKHPSEALFFTHMLPLPGFLIMAGNIVQHFGIAWSSEPVAVPLLGAIGLEWKFPLMLFYLLCNVVTQYVCISAVYVLTTECASLTVTLVVTLRKFVSLLFSIIYFRNPFTLNHWVGTILVFFGTILFANVINQVRDAYRARSSRKTHFDTAPLAKKVE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VAN9-1", "uniprot_id": "Q9VAN9_DROME", "id": "Q9VAN9-1", "name": "UDP-xylose and UDP-N-acetylglucosamine transporter", "aln": "MNLSIRAISAICGVFLGCCSGVVFLELLVKLDPG-AGNLITGAQFAFIALEGFIFTSKFGL-----AQRVISLRDYALLVAMFFLTSVCNNYVFKFKVPMTLHMIIRGGSLISNMCLCTLILKRSYRLSQYISVLMISVGIFVCTYFSSPDLVGKMEN---LDSGAEADT-FWWLLGVALLVLALFVSSYMGITQELLYRRHGKCAREALYYTHLLPLPAFLLMHDDIRTHWLLAFTGESYQLPLLGVA-----VPLILLYLLGNVLAQHLCISSVYTLTTECSSLTVTLILTLRKFISLVFSIVYFRNPFTWWHWLGTALVFVGTLMFANVIRVPK-----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40004-1", "uniprot_id": "YEA4_YEAST", "id": "P40004-1", "name": "UDP-N-acetylglucosamine transporter YEA4", "aln": "---MWNSLKAFALVFGGCCSNVITFETLMSNETGSINNLITFCQFLFVTCQGLPEFLDVHQPFPYFKPLKTPLHVYVITVVLFYISSTTNNNVFKYNISIPIHIVFRCFGTVITMFTCWLLNGRKYTKIQILSTLFLTIGAIIASLFKDADFRYQDLKLQAWKIGSDQSVDLTFIFGICILVLSSFTSSLLSAYNERTYQKYGKHWKENIFYSHFLSLPLFLFSRKQLIHEYRVMRKSERILCSNFGGK---ILVPREETLLLFNVLTQYFCVKGVNILASKTNALTLSITLLVRKFISLLLSVRLFDNNLSYTGYIGVYLVFFGAFIYSLGSIHPRQNDKGAIKKSK------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. .. ** ****.*: :* : .* .*::* .** *:: :*: .. .: *.: *.:*: .. ** .:. ::.:.:*:::* . : .* :: . * : * ::: * ::.: .. :. : . . : .*: *.:: : :: :. :* *::.** * :::.* *.** *:: :: . : . . :* .* ** *:::*:.*: .* *::: :**::: : :***:**::*: * * :: ::*. .** *::::: ", "identical_positions": 61, "similar_positions": 122, "identity": "16.94%" }, { "cls_id": "homologset.agr.RGD:1308986", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "B2RRL2-1", "uniprot_id": "JERKL_MOUSE", "id": "B2RRL2-1", "name": "Jerky protein homolog-like", "aln": "-MSGKRKRVVLTIKDKLDIIKKLEDGGSSKQLAVIYGIG-ETTVRDIRKNKEKIITYASSSDSTSLLAKRKSMKPSMYEELDKAMLEWFNQQRAKGNPISGPICAKRAEFFFYALG---MDGDFNPSAGWLTRFKQRHSIREINIRNERLNGDETAVEDFCNNFRDFIEQENLQPEQIYNADETGLFWKCLPSRTTVIKGKCTVPGHNLGEERITVMCCTNATGLHKLKLCVVGKARKPRSFK-----------------STDTLNLPVSYFSQKGAWMDLSIFRQWFDKIFVPQVREYLRSKGLQEKAVLLLDNSPTHPNENVLRSDDGQIFAKY---LPPNVASLIQPLGQGVIAAMKRNYRAGLLHNNLEEGNDLKSFWK---------KLTLLDALYEIAMAWNLVKPVTISRAWKQ--ILP----AIEEKEGLDFD-EDISGATVATILQH------------------TKGLENVTPENLEKWLEIDSTEPGYEVLTDSEIIRRAQGQTDESSENDEERIELIPEKHINHTTALQ--WTENLLDYLEQQG------------DMILPDRLVIRKLRATIRNKQKMTNPGQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "M0R5M5-1", "uniprot_id": "M0R5M5_RAT", "id": "M0R5M5-1", "name": "", "aln": "-MSGKRKRVVLTIKDKLDIIKKLEDGGSSKQLAVIYGIG-ETTVRDIRKNKEKIITYASSSDSTSLLAKRKSMKPSMYEELDRAMLEWFNQQRAKGNPISGPICAKRAEFFFYALG---MDGDFNPSAGWLTRFKQRHSIREINIRNERLNGDETAVEEFCNHFRDFIEQENLQPEQIYNADETGLFWKCLPSRTAVVKGKCTVPGHNSGEERITVMCCTNATGLHKLKLCVVGKARKPRSFK-----------------STDTFNLPVSYFSQKGAWMDLSIFRQWFDKIFVPQVREYLKSKGLQEKAVLLLDNSPTHPNENVLRSDDGQIFAKY---LPPNVASLIQPLGQGVIATMKRNYRAGLLHNNLEEGNDLKSFWK---------KLTLLDALYEIAMAWNFVKPVTISRAWKQ--ILP----AMEEKEGLDFDEEDISGATVATILQH------------------TKGLENVTPESLEKWLEIDSTEPGYEVLTDSEIIRRAQGQTDESSENDEEGIELIPEKHINHTTALQ--WTENLLDYLEQQG------------DMILPDRLVIRKLRATIRNKQKMTNPSQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y4A0-1", "uniprot_id": "JERKL_HUMAN", "id": "Q9Y4A0-1", "name": "Jerky protein homolog-like", "aln": "-MSGKRKRVVLTIKDKLDIIKKLEDGGSSKQLAVIYGIG-ETTVRDIRKNKEKIITYASSSDSTSLLAKRKSMKPSMYEELDRAMLEWFNQQRAKGNPISGPICAKRAEFFFYALG---MDGDFNPSAGWLTRFKQRHSIREINIRNERLNGDETAVEDFCNNFRDFIERENLQPEQIYNADETGLFWKCLPSRISVIKGKCTVPGHKSIEERVTIMCCANATGLHKLKLCVVGKAKKPRSFK-----------------STDTLNLPVSYFSQKGAWMDLSIFRQWFDKIFVPQVREYLRSKGLQEKAVLLLDNSPTHPNENVLRSDDGQIFAKY---LPPNVASLIQPSDQGVIATMKRNYRAGLLQNNLEEGNDLKSFWK---------KLTLLDALYEIAMAWNLVKPVTISRAWKK--ILP----MVEEKESLDFDVEDISVATVAAILQH------------------TKGLENVTTENLEKWLEVDSTEPGYEVLTDSEIIRRAQGQADESSENEEEEIELIPEKHINHAAALQ--WTENLLDYLEQQG------------DMILPDRLVIRKLRATIRNKQKMTKSSQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P32896-1", "uniprot_id": "PDC2_YEAST", "id": "P32896-1", "name": "Protein PDC2", "aln": "MLSIQQRYNICLMAERHPKWTQLELAKWAYETFQLPKIPSQGTISRLLARKSTYMNCKEHEKDANRLRKPNNLL------VRKILQEWISQSLWNGIPITSPIIQDTAQAVWHRIPAEHREGNGSFSYKWISNFLSKMDVNISVLDEELPKTPKVWTFEERDVLKAYFS--KIPPKDLFTLDEA-----FLSYNLPLDYAQYEASSIQRRIEVATVMLCSNLDGSEKLKPVVVGKYDSYKSFRNYFPNEPNDPVSQSMLGTKMAKKFDISYHSNRKAWLTSNLFHNWLVRWDKRLVAVNRKIWIVLDDSCCHRIINLRLQNIKLVYTSSNSKFLPFNWGVWDEFKTRYRIQQYQALIDLQNRISKNIQNKNKSERNECIPNGKKCLISFEQSQLTMSNAFKFIKKAWDDIPVDAIKANWKSSGLLPPEMIHLNENVSMAFKKNEVLESVLNRLCDEYYCVKKWEYEMLLDLNIENKNTNFLSTEELVESAIVEPCEPDFDTAPKGNEVHDDNFDVSVFANEDDNNQNHLSMSQASHNPDYNSNHSNNAIENTNNRGSNNNNNNNGSSNNINDNDSSVKYLQQNTVDNSTKTGNPGQPNISSMESQRNSSTTDLVVDGNYDVNFNGLLNDPYNTMKQPGPLDYNVSTLIDKPNLFLSPDLDLSTVGVDMQLPSSEYFSEVFSSAIRNNEKAASDQNKSTDELPSSTAMANSNSITTALLESRNQAQPFDVPHMNGLLSDTSKSGHSVNSSNAISQNSLNNFQHNSASVAEASSPSITPSPVAINSTGAPARSIISAPIDSNSSASSPSALEHLEGAVSGMSPSSTTILSNLQTNINIAKSLSTIMKHAESNEISLTKETINELNFNYLTLLKRIKKTRKQLNSESIKINSKNAQDHLETLLSGAAAAAATSANNLDLPTGGSNLPDSNNLHLPGNTGFF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* ::: : : :: .:** . : : : * : *: : .*.. :. . ...:. * * :.: : : : **:.*. :* **:.** . *: .:: : :*: . * *::.* .: .:. : :* : :. . : : :: ::. :: *::::. **: *. . .: .: ... : * *:* *:* * .*** **** . :**: :. : :: :**.*:: **: .:*::*: : * : : :.: . * ::: :.... * : : :. : : .: ::.. .: ::* .* *: . * :**: :*: * **: : :*. **. :** ::*: .: *. ::: :.: : :. .*. : ::.*.* : ::. **.::. ...: :: : :.. :::::: : :. .: .* . : ::* :: :::* :: * * : *: *. * :..* ", "identical_positions": 82, "similar_positions": 222, "identity": "8.74%" }, { "cls_id": "homologset.agr.RGD:1308989", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q2KHK6-1", "uniprot_id": "GSDC2_MOUSE", "id": "Q2KHK6-1", "name": "Gasdermin-C2", "aln": "MGYSFDRASKDVVKKLQGRDLRPVECLSDATKFRLFHILQETP---RSGWE-TEDIPVGFTLLDLLEPNFPVPEPEVSAPKPFIHVQSTDLEANLNV-ADIARGGVG--YVGYGGYNIEVQSTSIPNPKLEILQNR-----KLLDNLPTFMKFCRMERKNLYVVTEAYEVSKDTMLTGLSSVNLSVK-GFFKQLFKVRG-KAGRSEK-YSIPIPKGSVLAYKKQQLVIENNTCVILPSA-------------------TKKKMTFPGT----PKYASASEPTEIYRTEL--QGLWIN---------DIVPIGRIQEPAHLDFMCLQNEVYKQTEQLAELSKGVQEVVLSSILSMLYEGDRKVLYDLMNMLELNQLGHMDGPGGKILDELRKDSSNPCVDLKDLILYLLQALMVLSDSQLNLLAQSVEMGILPHQVELVKSILQPNFKYPWNIPFTLQPQLLAPLQGEGLAITYELLEECGLKMELNNPRSTWDLEAKMPLSALYGSLSFLQQLRKANSSSKPSLRPGYI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8CB12-1", "uniprot_id": "GSDC3_MOUSE", "id": "Q8CB12-1", "name": "Gasdermin-C3", "aln": "MGYSFDRASKDVVKKLQGRDLRPVECLSDATKFRLFHILQETP---RSGWE-TEDIPVGFTLLDLLEPNFPVPEPEVSAPKPFIHVQSTDLEANLNV-ADIARGGVG--YVGYGGYNIEVQSTSIPNPKLEILQNR-----KLLDKLPTFMKFCRMERKNLYVVTEAYEVSKDTMLTGLSSVNLLVK-GFFKQLFKVRG-KAGRSEK-YSIPIPKGSVLAYKKQQLVIENNTCVILPSA-------------------TKKKMTFPGT----PKYASASEPTEIYRTEL--QGLWIN---------DIEPIGRIQEPAHLDFKCLQYEVSEQTRLLPELSKDVQEVVLSSFLSMLYEGDRNVLHDLMKMLELSQLGHMDGPGGKILDELRKDSSNPCVDLKDLILYLLQALMVLSDSQLNLLARSVEMRLLPHQVELVTSILQPNFKYPWNIPFTVQPQLLAPLQGEGLAITYELLEECGLKMELNNPRSTWDLEAKMPLSALYGSLSFLQQLQKANSSFKPSLRPGYI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3TR54-1", "uniprot_id": "GSDC4_MOUSE", "id": "Q3TR54-1", "name": "Gasdermin-C4", "aln": "MGYSFDRASKDVVKKLQGRDLRPVECLSDATKFRLFHILQETP---RSGWE-TEDIPVGFTLLDLLEPNFPVPEPEVSAPKPFIHVQSTDLEANLNV-ADIARGGVG--YVGYGGYNIEVQSTSIPNPKLEILQNR-----KLLDKLPTFMKFCRMERKNLYVVTEAYEVSKDTMLTGLSSVNLLVK-GFFKQLFKVRG-KAGRSEK-YSIPIPKGSVLAYKKQQLVIENNTCVILPSA-------------------TKKKMTFPDR----PLKLYDLPVTLRYQEEVIETGSWID---------DIDPIGTIEEPANLNFMCLQHEVSEQTQLLAELSKDVQEVVFSSFLHMLS--DRDVLYDLMKMLELNQLGHMDGPGGKILDELRKDSSTPHDVLKDLNLYLLQALLVLSDTQLCLLAQSVKMGLLPHQVELVKSILQTNFKYSSNTPFTLQPQLLAPLQGEGLAITYELLEECGLKMELNNPRSTWDLEAKMPLSALYGSLSFLQQLQKANSSSKPSLSPGYI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99NB5-1", "uniprot_id": "GSDMC_MOUSE", "id": "Q99NB5-1", "name": "Gasdermin-C", "aln": "MSYTFDWLSKDVVKKLQGRDLRPVKCLSDATKFCLFNILQETSS--RLALK-TEYIPVGFTLLHLLEPNIPVPEPEVSAPIPLKHTISQKLKADLDV-ETIAGGEAG--FVKSCGYDIEVQSKSIPNPKLESLQNR-----KLLDQLPTFMKTCWKDGKNLYVVTEAYEVTKDTVLEGTSNSKFAIK-GIINQLVKVGGSGQWQTEKTDSIPIQKGSVLAYKKQQLVIEDNTCVILTSAN------------------TKKKMTFP-------MRFVGMSGHLRYQDLVIETGSWIN---------DIDPIGTIKEPTHLDFMCLQNEVSEQTRLLAELSKDVQEVVFSSFLHMLC--DRDVLYDLMKMLELNQLGHMDGPGGKILDELRKDSSLSWINLKDLILYLLQALMVLSDTQLCLLALSVEMRLLPHQVELVKSILQPNFKYPWNIPFTLQPQLLAPLQGEGLAITYELLEECGLKMELNNPRSTWDLEAKMPLSALYGSLSFLQQLSEA-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P85967-1", "uniprot_id": "GSDMC_RAT", "id": "P85967-1", "name": "Gasdermin-C", "aln": "MLYTFDQVSKDVVKKLQGKDLRPVRCLSDATKFRQFDILQKTPQ--SLFFK-SEDTPVGYSLLQILEPNFPVPETEVSAPMPLKHITSQKWKADVDVKATIADGGASAEFVQSCGYDIEVQSRSIPDSKLESLQNRQGPWGKLLDKKLSFVTDCQMGRNNLYVVTEVFEVTKDTVVQGSSSIDLSGK-ALVSQLVKGEAQGQWQRETTDLVPIPKGAVLAYKKKQLVIENNTCAILLSA-------------------NAKKKTFPG--------IFNFGMSSRSQTMEIVNSSWID---------YIPPIGRIEEPVHLDFKYLEKEVFLRKEQLAMLSKDVQDVVFSNLLPMLS--DSDVLFDLINMLELDQLGHMDGPAGLILDELRKNSSTPWIDLKGLILYLLQALMVLSDTQLDLLAQSMEMRILLQQRELVRSILEPNFKYPWNIPFTLQPQLLAPLQGEGLAITYELLKGCGLKMEPNSPRSTWDLEAKMPLSALYGILSCLQQLVEA-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BYG8-1", "uniprot_id": "GSDMC_HUMAN", "id": "Q9BYG8-1", "name": "Gasdermin-C", "aln": "MPSMLERISKNLVKEIGSKDLTPVKYLLSATKLRQFVILRKKKDSRSSFWEQSDYVPVEFSLNDILEPSSSVLETVVTGPFHFSDIMIQKHKADMGVNVGIEVSVSGEASVDHG-CSLEFQIVTIPSPNLEDFQKR-----KLLDPEPSFLKECRRRGDNLYVVTEAVELINNTVLYDSSSVNILGKIALWITYGKGQGQGESLRVKKKALTLQKGMVMAYKRKQLVIKEKAILISDDDEQRTFQDEYEISEMVGYCAARSEGLLPSFHTISPTLFNASSNDMKLKPELFLTQQFLSGHLPKYEQVHILPVGRIEEPFWQNFKHLQEEVFQKIKTLAQLSKDVQDVMFYSILAMLR--DRGALQDLMNMLELDSSGHLDGPGGAILKKLQQDSNHAWFNPKDPILYLLEAIMVLSDFQHDLLACSMEKRILLQQQELVRSILEPNFRYPWSIPFTLKPELLAPLQSEGLAITYGLLEECGLRMELDNPRSTWDVEAKMPLSALYGTLSLLQQLAEA-------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :: **::**:: .:** **. * .***: * **::. : :: ** ::* .:***. .* *. *:.* : . . :*::.* * . . * .:*.* :**..:** :*:* **** :*:. * .*******. *: ::*:: . *. .: * .: * . . :.: ** *:***::****:::: * . .: :* : ::. * *:* *:** :* *: ** : . *. ***.**:*:: .:* ** * .* **::****.. **:***.* **.:*:::*. . *. ****:*::**** * *** *:: :* :* *** ***:.**:*. . ***::*:******.******* **: ***:** :.******:*********** ** **** :* ", "identical_positions": 180, "similar_positions": 130, "identity": "34.03%" }, { "cls_id": "homologset.agr.RGD:1308990", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZBY5-1", "uniprot_id": "D3ZBY5_RAT", "id": "D3ZBY5-1", "name": "ATP-dependent RNA helicase", "aln": "--MGKTVGSLGQGTRPDP-VRSFNRWKKKHSHRQHQKKERRKQLKKPEWQVEREGISRLMQNYEKIN--VNEITRFSDFPLSKKTLKGLQEAQYRLVTEIQKQTIGLALQGKDVLGAAKTGSGKTLAFLVPVLEALYRLQWTSTDGLGVLIISPTRELAYQTFEVLRKVGKNHDFSAGLIIGGKDLKHEAERINNINILVCTPGRLLQHMDETICFHATNLQMLVLDEADRILDMGFADTMNAIIENLPKKRQTLLFSATQTKSVKDLARLSLKDPEYVWVH----------------EKAKYSTPATLEQNYIICELHQKISVLFSFLRSHLTKKSIVFFSSCKEVQYLYRVFCRLRPGISILALHGRQQQMRRMEVYNEFVRKRAAVLFATDIAARGLDFPAVNWVLQFDCPEDANTYIHRAGRTARYKEDGEALLILLPSEEQGMVQQLLQKK-VPVKEINLTIIFFLLKRINPEKLIDVQKRLESFLAQDQDLKERAQRCFVSYIRSVYLMKDKEVFDVNKLPITEYALSLGLAVAPRIRFLQKMEKQPNKELGKNQVTEAIQPRAPSLTSDEVEEFRAYFSEKMSILHKSGKRLEETEHSLASGE-SEEQDEETEDEE-MEDHVGQTREPPTDSVPRSEEAQKVKEVPVQFLDRDDDEEDGPDADFLTVKRRDVFGLDLKENEALSKKEPSKSSVKKKLTKVAEAKKVMKRNFKVNKKITFTDEGE-LVQQWPQIQKCATND--VEEEDDTGGINLDKAKERLQEEDKFDKEEYRKKIKAKHRERRLKEREARREANKRQAKARDEEEAFLDWSDEDDG---GFDPSTLPDPDKHRSSEESESEDTKHKMSDTKKKQEMRKR-NNTEVDDVRPRSRHGKKAKWETLEPLDTGLSLAEDEELVLHLLKSQN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80Y44-1", "uniprot_id": "DDX10_MOUSE", "id": "Q80Y44-1", "name": "Probable ATP-dependent RNA helicase DDX10", "aln": "--MGKTVASLGQGTRPDP-VRSFNRWKKKHSHRQHQKKERRKQLKKPEWQVEREGISRLMQNYEKIN--VNEITRFSDFPLSKKTLKGLQEAQYRLVTEIQKQTIGLALQGKDVLGAAKTGSGKTLAFLVPVLEALYRLQWTSTDGLGVLIISPTRELAYQTFEVLRKVGKNHDFSAGLIIGGKDLKHEAERINNINILVCTPGRLLQHMDETICFHATNLQMLVLDEADRILDMGFADTMNAIIENLPKKRQTLLFSATQTKSVKDLARLSLKDPEYVWVH----------------EKAKYSTPATLEQNYIICELHQKISVLFSFLRSHLKKKSIVFFSSCKEVQYLYRVFCRLRPGISILALHGRQQQMRRMEVYNEFVRKRAAVLFATDIAARGLDFPAVNWVLQFDCPEDANTYIHRAGRTARYKEDGEALLILLPSEEQGMVQQLLQKK-VPVKEI----------KINPEKLIDVQKKLESFLAQDQDLKERAQRCFVSYIRSVYLMKDKEVFNVSKLPITEYALSLGLAVAPRIRFLQKLEKQPSTELVKNPVTEAVPPRAPSLPNDEADESPAYVSEKMSVLHKSGERLEETEHRLASGDGDEEQDEETEDEE-TEDHLGKAREPHTESVVSIEEAQKVKEVSVQFLNRDDDDEDGPDADFLTVKRRDVFGLDLKENEALSKKEPSKSSVKKKLTKVAEAKKVMKRSFKVNKKITFTDEGE-LVQQWPQIQKCAIKD--VEEEDDTGGINLDKAKERLQEEDKFDKEEYRKKIKAKHRERRLKEREARREANKRQAKARDEEEAFLDWSDEDDG---GFDPSTLPDPDKHRSSEESESEDTNHKMSDTKKKQETRKR-NNTEDDDVRPRSRHGKKAKWETVEPLDTGLSLAEDEELVLHLLKSQN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13206-1", "uniprot_id": "DDX10_HUMAN", "id": "Q13206-1", "name": "Probable ATP-dependent RNA helicase DDX10", "aln": "--MGKTANSPGSGARPDP-VRSFNRWKKKHSHRQNKKKQLRKQLKKPEWQVERESISRLMQNYEKIN--VNEITRFSDFPLSKKTLKGLQEAQYRLVTEIQKQTIGLALQGKDVLGAAKTGSGKTLAFLVPVLEALYRLQWTSTDGLGVLIISPTRELAYQTFEVLRKVGKNHDFSAGLIIGGKDLKHEAERINNINILVCTPGRLLQHMDETVSFHATDLQMLVLDEADRILDMGFADTMNAVIENLPKKRQTLLFSATQTKSVKDLARLSLKNPEYVWVH----------------EKAKYSTPATLEQNYIVCELQQKISVLYSFLRSHLKKKSIVFFSSCKEVQYLYRVFCRLRPGVSILALHGRQQQMRRMEVYNEFVRKRAAVLFATDIAARGLDFPAVNWVLQFDCPEDANTYIHRAGRTARYKEDGEALLILLPSE-KAMVQQLLQKK-VPVKEI----------KINPEKLIDVQKKLESILAQDQDLKERAQRCFVSYVRSVYLMKDKEVFDVSKLPIPEYALSLGLAVAPRVRFLQKMQKQPTKELVRSQADKVIEPRAPSLTNDEVEEFRAYFNEKMSILQKGGKRLEGTEHRQDNDTGNEEQEEEEDDEEEMEEKLAKAKGSQAPSLPNTSEAQKIKEVPTQFLDRDEEEED---ADFLKVKRHNVFGLDLKDEKTLQKKEPSKSSIKKKMTKVAEAKKVMKRNFKVNKKITFTDEGE-LVQQWPQMQKSAIKD--AEEDDDTGGINLHKAKERLQEEDKFDKEEYRKKIKAKHREKRLKEREARREANKRQAKAKDEEEAFLDWSDDDDDDDDGFDPSTLPDPDKYRSSEDSDSEDMENKISDTKKKQGMKKR-SNSEVEDVGPTSHNRKKARWDTLEPLDTGLSLAEDEELVLHLLRSQS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VX34-1", "uniprot_id": "Q9VX34_DROME", "id": "Q9VX34-1", "name": "ATP-dependent RNA helicase", "aln": "MQRQKPKGPGKPGSRFKPGSGTFKGAGGGRKSGDNSQKRPRQEINKSRLAATEAEIQDLKTKYAEID--ATAIKKFAQFPLSKKTQKALAESKFVHPTQVQRDSIGPALQGKDVLGAAITGSGKTLAFLIPVLEHLFMNKWSRTDGVGAIIISPTRELAYQIFETLKKVGKHHDFSAGLIIGGKNLKFERTRMDQCNILICTPGRLLQHMDENPLFNTSTMEMLVLDEADRCLDMGFQKTLNSIIENFPPVRQTLLFSATQTNTVQDLARLNLKDPVYVGYGGATPREEPSASTKKTPNTAVLAVPELLQQSYVVLNLEDKITMLWSFIKNHLKQKIIVFVASCKQAKYLYEIFCKLRPGSPLLALYGTLHQDRRIAIYEDFLRKSHVVMFSTDVASRGLDFPAVNWVVQLDCPEDVSQYIHRAGRSARNKTRGECLLVLTPSEEEYMISALKEQLNIDIRCV----------QIDPKKLFSPRVKIEAFLAQFPELRATAQRAFLSYIKSVFLMRNKRLFNVFSLDLDAFAQSLGLAVTPRVPFLEKFLWR-QKQLQQ---------------QKEQGDNAKSINPLLSKLTK-----------QQSFGGGDEDEENSDDED-----FIKVK----------RKDHDVEGEPVK-LDEEDDTENEAEAPLVVPKR------------------------EKLVTKASLAKKALKKNLQVNSKLKFDDEGETMADDRSQMKALSARQRTVNQDDDDGGINLVLSKALLTEEDQYDKQRFRELVKKRHKLQREKLRKKAEEAKGSDDEEEQQDDDNADDAGSESD--HSVDLSWLPDPDKVYKNKPNASDRNESKSESSDASDDEKADDSDGDDDDVSDDEPAYKKSK------LTNKMTLMDTEAIAASLLGS--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P20448-1", "uniprot_id": "DBP4_YEAST", "id": "P20448-1", "name": "ATP-dependent RNA helicase HCA4", "aln": "---------------------------------MAKKNRLNTTQRKTLRQKEDEYIENLKTKIDEYDPKITKAKFFKDLPISDPTLKGLRESSFIKLTEIQADSIPVSLQGHDVLAAAKTGSGKTLAFLVPVIEKLYREKWTEFDGLGALIISPTRELAMQIYEVLTKIGSHTSFSAGLVIGGKDVKFELERISRINILIGTPGRILQHLDQAVGLNTSNLQMLVLDEADRCLDMGFKKTLDAIVSTLSPSRQTLLFSATQSQSVADLARLSLTDYKTVGTHDVMDG----------SVNKEASTPETLQQFYIEVPLADKLDILFSFIKSHLKCKMIVFLSSSKQVHFVYETFRKMQPGISLMHLHGRQKQRARTETLDKFNRAQQVCLFATDVVARGIDFPAVDWVVQVDCPEDVDTYIHRVGRCARYGKKGKSLIMLTPQEQEAFLKRLNARKIEPGKLN-----------IKQSKKKSIKPQLQSLLFKDPELKYLGQKAFISYVRSIYVQKDKQVFKFDELPTEEFAYSLGLPGAPKIKMKGMKTIEQAKERKN---------------APRQLAFLSKANEDGEVIED---------KSKQPRTKYDKMFERKNQTILSEHYLNITK----------AQAQEDEDDDFISVKRKDHEINEAELPALTLPT------------------------SRRAQKKALSKKASLASKGNASKLIFDDEGE--AHPVYELEDEEEFHK-RGDAEVQKTEFLTKESAVMADIDNIDKQVAKEKKQEKKRKRLEAMRREMEAAMEEEISGDEEEGKTVAYLG----------TGNLSD-DMSDGDMPDSEGHLKKKARTVDYSHGHNPS--NSVDDDIIEVEEP---------------QTLEDLESLTAKLIQG--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .::. . .*. *. * : : : . . * ::*:*. * *.* *:.: *::* ::* :***:***.** **********:**:* *: :*: **:*.:********* * :*.* *:*.: .*****:****::*.* *:.. ***: ****:***:*: :::: ::********* ***** .*:::::..:. **********:::* *****.*.: * . :.* *:* *: * :*: :*:**::.**. * ***.:*.*:.:::*. * :::** .:: *:* :* * :.* * . :*:**:.:**:*****:**:*.*****.. ****.** ** *:.*::* *.* : ::. * : : *. .* . : :::::* : :*: .*:.*:**::*::: ::*.:*.. .* :* ****. :*:: : . .: . . . . : . :: *. :: . .: : :. : :...:. : : .: * : :**. . .*: * **** .. ::: . : : * . : : *: **: :: : ::: : *. . * : . ::: . . *.* * . . . : * . .. . : :*: . :* : * :. *: . ", "identical_positions": 210, "similar_positions": 250, "identity": "22.95%" }, { "cls_id": "homologset.agr.RGD:1308992", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZK09-1", "uniprot_id": "D3ZK09_RAT", "id": "D3ZK09-1", "name": "", "aln": "------MGSENSALKSYTLGEPPYTLPSGLAVY----PAVLQDGKCASVFVYKR-----------ENEDKVNKAAKHLKTLRHPCLLRFLSCTV-EADGIHLVTERVQPL---EVALETLSPAEVCAGIYDILLALVFLHERGHLTHNNVCLSSVFVSEDGHWKLGGMETVCKVSQATP-EFLRSIQSVRDPASIPPEEMSPDFAALPESHGHARDAYAFGALVDSLLPIFN----EQVSADVLSSFLQTLHSALLSPTPTCRPALSTLLSHDFFRNDFLEVVNFLKSLTLKSEDEKTEFFKFLLDRVSCLSEELIASRLVPLLLNQLVFAEPVAVKSFLPYL-LGPKKENAPGETPCLLSPALFQSRVIPV-----LLQLFEVHEEHVRMVLLSHIEAYVEHFTQEQLKKVILPQVLLGLRDTSDSIVAITLRSLAVLVSLLGPEVVVGGQRSKIFKRTAPSFTKTSDLSPEGSPMHVVCSQQSRISKVLENPSSNVFPK-WFSGNMSINSRKHIQEEYYSTLLQT----------------DVKNTSEDNGSFPAGSNKPEEWPDWSEPEEPEHQTTSIHIWPQEPGDVAETQHTSLSAQELSWDDCE-SSFGPEVN---TAARASAPRPVTSGEQMPTAALLPLTEESKPVQ--SRPSSKTSHRQQ----EEVKAPQMS-QERPPQVRSELGLGEEFTIQVKKKPAQDPELDWFADMVPEIK--PSGTFLILPELRTEGMVPDKDTVSPVMQFSSKFAATEMTEG-------------EAEGWEGE-ELAWEDDNW---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DBQ7-1", "uniprot_id": "PACE1_MOUSE", "id": "Q9DBQ7-1", "name": "Protein-associating with the carboxyl-terminal domain of ezrin", "aln": "------MGSENSALKSYTLRESPFTLPSGLAVY----PAILQDGKCASVFVYKR-----------ENEDKVNKAAKHLKTLRHPCLLRFLSCTV-EADGIHLVTERVQPL---EVALETLSPAEVCAGIYDILLALIFLHDRGHLTHNNVCLSSVFVSEDGHWKLGGMETVCQVPQATP-EFLRNIQSVRDPASIPPEEMSPEFSGLPESHGHARDAYAFGALVDSLLPIFN----EQVSADVLSSFLQILHSALLNPMPECRPALSTLLSHDFFRNDFLEVVNFLKSLTLKSEDEKTEFFKFLLDRVSCLSEELIASRLVPLLLNQLVFAEPVAVKSFLPYL-LGPKKENAPGETPCLLSPALFQSRVIPV-----LLRLFEVHEEHVRMVLLSHIEAYVEHFTQEQLKKVILPQVLLGLRDTSNSIVAITLRSLAVLVSLLGPEVVVGGERTKIFKRTAPSFTKTSDLSPEGSPMHVVCSQQSRVSKVLEDPSSNVFPK-WLSGNVPSSSRKRIQEECYSSLSQTGDQFSHTIKFPMNGLSDVKNTSEDNGSFPAGSNKPEEWPDWSEPEEPEQQPASIHRWPREPCDVAESQHTNLTAEEVTWDDGE-ASFGTEIN---STATASAPVPVTSGGQSTSAALVPLTEESKPLQ--SSPSSKTSHRQH----EEVKPPQVS-QERPLKAPSGLGLGEEFTIQVKKKPVQDPELDWFADMIPEIK--PSGTFLILPELRTEVMVPDKDNVSSLMQFSSKFAATEMTEG-------------EAEGWEGE-ELAWEDNNW---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IZE3-1", "uniprot_id": "PACE1_HUMAN", "id": "Q8IZE3-1", "name": "Protein-associating with the carboxyl-terminal domain of ezrin", "aln": "------MGSENSALKSYTLREPPFTLPSGLAVY----PAVLQDGKFASVFVYKR-----------ENEDKVNKAAKHLKTLRHPCLLRFLSCTV-EADGIHLVTERVQPL---EVALETLSSAEVCAGIYDILLALIFLHDRGHLTHNNVCLSSVFVSEDGHWKLGGMETVCKVSQATP-EFLRSIQSIRDPASIPPEEMSPEFTTLPECHGHARDAFSFGTLVESLLTILN----EQVSADVLSSFQQTLHSTLLNPIPKCRPALCTLLSHDFFRNDFLEVVNFLKSLTLKSEEEKTEFFKFLLDRVSCLSEELIASRLVPLLLNQLVFAEPVAVKSFLPYL-LGPKKDHAQGETPCLLSPALFQSRVIPV-----LLQLFEVHEEHVRMVLLSHIEAYVEHFTQEQLKKVILPQVLLGLRDTSDSIVAITLHSLAVLVSLLGPEVVVGGERTKIFKRTAPSFTKNTDLSLEDSPMCVVCSHHSQISPILENPFSSIFPKCFFSGSTPINSKKHIQRDYYNTLLQTGDPFSQPIKFPINGLSDVKNTSEDSENFPSSSKKSEEWPDWSEPEEPENQTVNIQIWPREPCDDVKSQCTTLDVEESSWDDCEPSSLDTKVN---PGGGITATKPVTSGEQKPIPALLSLTEESMPWK--SSLPQKISLVQRGDDADQIEPPKVSSQERPLKVPSELGLGEEFTIQVKKKPVKDPEMDWFADMIPEIK--PSAAFLILPELRTE-MVPKKDDVSPVMQFSSKFAAAEITEG-------------EAEGWEEEGELNWEDNNW---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1Z6G6-1", "uniprot_id": "A1Z6G6_DROME", "id": "A1Z6G6-1", "name": "PIK3R4-like middle domain-containing protein", "aln": "------MGNEGSKLKGILVEENAVETNQFWTVYNAKTPETTNDERCSQMLSVFEGKVFVKAHVWSNGVGPIERAIKNLMVYRHPYILKYIATWE-KSGRKYLATERVRPL---DEVLAQQTDIEVCLGLRTILCALIFLVEKALARHLNINTQSIYVTESGSWRLAGFEYVWRATDVNK-QLLDLAHSFIDLT----------------IHGENFEQFFFSILCEKVLSRKGTDSCITDSTPHVHEFREYCSTHLKHQNTKLRPRLSAILLHPYFNHEFVLIHSFLFELPLKSVHERHKFFRSLIDRLRYFDEEVVASQLACDLLSRMVLLDPAAQEFVTPHI-LRTKVTDKAPAS--LFSPQIYVQYLMPH-----ILKMFRLRDAQIRLILLDYFMDYVRLLSDEQLESEILPHLQLGMNDTNDVLVGKTLRCMADLVSILGANKVLGGDRARCFSDGRPHAAVSRDSNNPYPEPRSISPLMNTRSFDVEDFMVSGSPLPQESNASPLSIR------------------------------LSPDGGEDEKLRLNSNEKSISIKHNIDPEKDSYISG---------TEHERVANIDEEGTWLDWDNTDHLQQGYQVD---HAVTDSETNSNSFAREIQTGKSLSPSYRTGKCN--LSVGVNETISQT--------------EQKVIDDLSELDIKVQTVIQRS----EFNEFDFFKDMEPIIE--IRTSTCETPEQISSRFAAAASAVN-----CNELCADQGWGH-------------DEQ--DDKDDIVWGVTNVSTL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12453-1", "uniprot_id": "CEX1_YEAST", "id": "Q12453-1", "name": "Cytoplasmic export protein 1", "aln": "MNFSSIFKSISNFQFPYTIEETAITETALWQCFDG---TRKADSLPVTVFKAKRS---------PENESLILNAVHKSKILKIPGLCTVLETFDSDPQSTFIVTERVVPFPWDNLGSLSQNKFGVELGISQLLATLGFLKN---FVLGTLSKDSVFINIKGEWVLFGLELCSSKEGLSAFEFASRARSYYNIIG----------SQLPCEDPNTIDSMGLGLLIKSLMAPSCLPKDWIVNVNMISDGKITIENFRKRLENTETWRSNPLIN---FYQELRELHIKDPQGKLVVMSNLENLYLESREIFRNLTPGMIENFIIPELCEIIKLLMTQSISSAASPIGMNFNASHKLVPFLAIVLDLTSETNTFPVGFNDLITQSFKLPDRQVRFLLLIYLPKLIGPLSKSEISSRIYPHFIQGLTDSDATLRLQTLKTIPCIVSCL-TERQLNNELLRFLAKTQVDSDVEIR-TWTVIIISKISTILSTSVGNRSNILATAFTKSLKDPQVKPRLAALYGLEKSIELFDVN--------TIANKILTVIAPGLLDKSPIVRGRAKILFEEYLEKLEKEAQLIQTNDSTADSEDVKDIDFENYGCDEEDMNKEDNLLAAQFLNNLRLNSPSATTPSNITESEIDSAQDGSGWDDLSDTDGFITNGTTESFDETTNPVTTASTPKLFGKPIKINKSWNDELNDDGWIQDESGPSKVPQKHTRPQNSTLAKSIAPSSRLSIKKKKTTILAPRNIASNSTVTTKSSLSNKTARSKPISSIRGSVTKKGNVDGWDDDGDSDSWDTNW---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . .. : * . : * :: . :. . : .* :: : * : : .. .:.**** *: : . * *: :* :* ** : .: .*:::. .* * * *:* . :: :* : . . : :. * ..::. .. : . . .:: * ::: : . * : ::: : . : :: . : * . : : . : . . : : : . :. :* : : *.: : ::*::** :: : ::..::.. * *:. *: *:. : **: :. :** * .: :..: : : . :.. . .: . . . . . .. . : : . : :. : :: : . . : . . . : : : . : : ** . : : . : . : : : : :.. . ..:. : : : . : * ", "identical_positions": 43, "similar_positions": 192, "identity": "5.36%" }, { "cls_id": "homologset.agr.RGD:1308993", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XI50-1", "uniprot_id": "MARH7_RAT", "id": "Q5XI50-1", "name": "E3 ubiquitin-protein ligase MARCHF7", "aln": "MESKPSRIPRRISVQPSGSLSARMVSGN----------RGTSLNDSYHSRDSSFRLDSEYQ-----------------------SASASASASPYQSTWYSESEITQGARSRSQNQQR-------------DHDSKRPKLSCTNCTSTSAGRNIGSGLNTLS--DSSWRPGQVPRS-----SSMVLGSFGTDLMRERRDLERRRDSSISSLMDYSHRSGDFTAPAYVQERVPSSYSQGARPKENAANTLQLN-SSTNHQLPSEHQTVPSSRDSS--RSSFRSHFSPRQ---SESFRNSS-HPAFSYLSSRNETPTISSSERA--------GSSQRPFQESSDNEGRRTTRRLLSRIASSMSSTFFSRRSSQDSLNTRSLSSEN--YISPRTLTS-QSRNNGASSS-EVNDGRASEASQGFRFLRRRWGLSSLSQNHSSEPDAENFNQESEGRNTGPWLSSSLRNRCTPLFSRRRREGRDESSRISPSDVPPRSHLFR---RESNEVVHLEAQGDSLGAAASRPQASGASG-NASASGSTPDLPQGGRNTGIAGILPGSLFRFAVPPALGSNLTDNVTITVDIIPSGWSSADGKSEKAKSAPSRDPEKLQKIKESLLLEDSDEEEEGDLCRICQMAAASSSNLLIEPCKCTGSLQYVHQECMKKWLQAKINSGSSLEAVTTCELCKEKLQLNLEDFDIHELHRAHANEQAEYEFISSGLYLVVLLHLCEQSFSDMMGNTIEPSTRVRFINLARTLQAHMEDLETSEDEF------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WV66-1", "uniprot_id": "MARH7_MOUSE", "id": "Q9WV66-1", "name": "E3 ubiquitin-protein ligase MARCHF7", "aln": "MESKPSRIPRRISVQPSGSLSTRMVSGN----------RGTSLNDSYHSRDSSFRLDSEYQ-----------------------SASASACASPCQPAWYSESEIPQGARARAQTQQR-------------DHDSKRPKLSCTNCASTSAGRNGGSGLNTVS--DSSWRHSQVPRS-----SSMVLGSFGTDLMRERRDLDRRRESSISNLMDYNHRSGDFTTSSYVQERVPSSYSQGARPKENAVSTLQLNSSSTNHQLPSDHQTVPSSRDSS--RSSFRSHFSPRQ---SESFRNSS-HPAFSYFSSRNETPTISNSER---------GSSQRPYRESSDNEGRRTTRRLLSRIASSMSSTFFSRRSSQDSLNTRSLSSEN--YISPRTLTS-QSRNNGTSSSSDVSEGRAAEASQGFRFLRRRWGLSSLSQNHSSEPEAENFNQESEGRNSGPWLSSSLRNRCTPLFSRRRREGRDESSRMSTSDVPPRSHIFR---RDSNEVVHLEAQGDSLGAAANRPQASGASS-SAAAGGSTPELPQGGRNPGLTGILPGSLFRFAVPPALGSNLADNVMITVDIIPSGWNSTDGKNDKAKSAPSRDPEKLQKIKESLLLEDSDDEEEGDLCRICQMAAASSSNLLIEPCKCTGSLQYVHQECMKKWLQAKINSGSSLEAVTTCELCKEKLQLNLEDFDIHELHRAHANEQAEYEFISSGLYLVVLLHLCEQSFSDMMGNTIEPSTRVRFINLARTLQAHMEDLETSEDEF------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H992-1", "uniprot_id": "MARH7_HUMAN", "id": "Q9H992-1", "name": "E3 ubiquitin-protein ligase MARCHF7", "aln": "MESKPSRIPRRISVQPSSSLSARMMSGS----------RGSSLNDTYHSRDSSFRLDSEYQ-----------------------STSASASASPFQSAWYSESEITQGARSRSQNQQR-------------DHDSKRPKLSCTNCT-TSAGRNVGNGLNTLS--DSSWRHSQVPRS-----SSMVLGSFGTDLMRERRDLERRTDSSISNLMDYSHRSGDFTTSSYVQDRVP-SYSQGARPKENSMSTLQLNTSSTNHQLPSEHQTILSSRDS---RNSLRSNFSSRE---SESSRSNT-QPGFSYSSSRDEAPIISNSERV--------VSSQRPFQESSDNEGRRTTRRLLSRIASSMSSTFFSRRSSQDSLNTRSLNSENS-YVSPRILTASQSRSNVPSAS-EVPDNRASEASQGFRFLRRRWGLSSLSHNHSSESDSENFNQESEGRNTGPWLSSSLRNRCTPLFSRRRREGRDESSRIPTSDTSSRSHIFR---RESNEVVHLEAQNDPLGAAANRPQASAASS-SATTGGSTSDSAQGGRNTGISGILPGSLFRFAVPPALGSNLTDNVMITVDIIPSGWNSADGKSDKTKSAPSRDPERLQKIKESLLLEDS-EEEEGDLCRICQMAAASSSNLLIEPCKCTGSLQYVHQDCMKKWLQAKINSGSSLEAVTTCELCKEKLELNLEDFDIHELHRAHANEQAEYEFISSGLYLVVLLHLCEQSFSDMMGNTNEPSTRVRFINLARTLQAHMEDLETSEDDSEEDGDHNRTFDIA-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NG75-1", "uniprot_id": "A0A8M1NG75_DANRE", "id": "A0A8M1NG75-1", "name": "RING-type E3 ubiquitin transferase", "aln": "MDSKSRRFPFAVSSSSSLSSPSSLSSSSSALSASRLYGRGSVLGRDRFSRDASVKLDSDYQGSRLLSSPRVYSSTESRHSNWKLSTPVTSSSSSSSSCDRSWTESSSGDRARLTDSERRLGTYCGLLGTSQDSESKRAKLSYTNREVYSRSPSTSKPATSYSTLGSSWKSSISPLSRSSSSSSSSSVSTQSEGLWARRDLEKRVDSGLSSLGESSYRPSSLTSSLYRSERVASTYAQGARPKDSQYSSHREN-SSSSRRIPSEYIPSPLERNSQRLTSDYQSNLFPRDTPRSSSTRTSTSVSDTSHHSSWSSTPYTALSACTSSPPSISPAPTPLPAQNTGESDGRGTTRRLLSR--------LFSRRSSQESNSTASTASDSRSYDSSPDEAPPTEAPPPISRENLEAELRNSDPAQAFSFLRRR-GPSLAPVQESTDVEPE---QESLRPPAG--LSWLNWNRCTPLFSRRRREGRDESARMDPHRSPQFSLGDRDGRKTPDQGTHCEDDDDEDDDDEDESSEGAAAGPSSGASALSASLLQDG--AHLAGRSHG-MGRGMNSPLFR--LPENVLIGVGVE--GRSQAD-EQPKDKPAPSRDPERLRKIQESLLLEES-DEEEGDLCRICQMGEQWSSNPLIEPCKCTGSLQYVHQDCIKKWLRSKISSGSNLEAITTCELCKEKLHLNIENFDINELYRSHE--RSEYEFISCGLYLVVLLHLCEQRFSDVLGAVNDAG----FFNLARTLHEHMDNLESSYAESDEDEVEDSRPSIDFCDLEDDDEEEEEEEEV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:**. *:* :* ..* * .: : *.. **: *. .***:*.:***:** *:..::.:*. .. * :* ..* *:* .:* * :***.*** ** * . . .. .: * .***: . * * ** * :: : ****::* :*.:*.* : .:*...:*:. * .:**. :*:******:. .: : * **:.:::**:: . .*:* .. :*:: .*: *.* *..: . *: ** ..:* : * .: * :::.:.:** ******** :*******:* .* * *:. * *. :. . * . : * ::.:*.* ***** * * . :.*:: :.* *** :* ** ******************:*: . . * * : .:: .* * :.* . .... ..*:. .: :.. :.. *.* . ::* * : * .* : *.:** * *.: * ..:* :. * *.*******:*:**:******:* :************. *** ****************:*:****::**.***.***:**********.**:*:***:**:*:* ::******.************* ***::* . :.. *:******: **::**:* : ", "identical_positions": 284, "similar_positions": 212, "identity": "35.59%" }, { "cls_id": "homologset.agr.RGD:1308994", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "O08692-1", "uniprot_id": "NGP_MOUSE", "id": "O08692-1", "name": "Neutrophilic granule protein", "aln": "MAGLWKTFVLVVALAVVSCEALRQLRYEEIVDRAIEAYNQGRQGRPLFRLLSATPPSSQNPATNIPLQFRIKETECTSTQERQPKDCDFLEDGEERNCTGKFFRRRQSTSLTLTCDRDCSREDTQETSFND-KQDVSEKEKFEDVPPHIRNIYEDAKYDIIGNILKNF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZY96-1", "uniprot_id": "D3ZY96_RAT", "id": "D3ZY96-1", "name": "", "aln": "MARLWKTFMLVVALAVVACEAHRRLRYEDIVNRAIEAYNRGQRGRPLFRLLSATPPPGQNPTSNVPLEFRIKETVCISTTERRLENCDFREGGEERNCTGEFSRRQWSTSLTLTCDRDCRREVSQVATFSDNKSDDSEKDKLEGLPPHAKNIYENAKYDIISNILHNF", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** *****:********:*** *:****:**:*******:*::*************..***::*:**:****** * ** **: ::*** *.********:* **: ************ ** :* ::*.* *.* ***:*:*.:*** :****:******.***:**", "identical_positions": 120, "similar_positions": 33, "identity": "71.43%" }, { "cls_id": "homologset.agr.RGD:1308995", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AKA1-1", "uniprot_id": "A0A8I6AKA1_RAT", "id": "A0A8I6AKA1-1", "name": "", "aln": "MKFPCSACSLVSLGMSGEHHHMDRDSRNMSLALEIMESFACVLEKPGRTFLCFGKFVVPISLTSSGAKTPGARALGLQRAEMTMTANKNSSITHGAGGTKAPRETLSRSQSVSPPPVLYPPRSPIYP-LSDSE--TSACRYPSHSKSQVLLKDRHSRNPSPLG-QDPSPDTSPPICTLKATSFSYLDRTPSLRR-----REDQRESVQGAVQDVEG--VAACLPLAQSTPFLG--SGPRSVLLSCTGTRAHNLGIREKISAWEGRREASPRMNLCGEKREGPGSERSVSEGCPSVGCPSVVPSPCSSEKTFDFKGLRRMSRTLSECSYPETEEESEALPVRDSLYRLEKRPSRTEPS-ALLRGHGIRKESSAVLSRIQKIEQALKEQPGCGLPQLPSSCYSVDHGRRKTGTLGTSEEPAGTASVSSSSRAGGATGVAREAGPPLDREGSGSMKSETPGN-SSSPQLLPSKSSPDPAVNPVPKPKRTFEYEADKNPKPK-PSNGLPPSPTPAAPPPLPSTPAPPVTRRPKKDIRGHRKSQNRKSFEFEDASSLQSLYPSSPTENGTESQPKFGSKSTLEENAYEDIVGGLPKENPYEDVDLKNRRAGRKSQQLSENSLDSLHRMWSPQDRKYNNPPMQLSLKPSSQSLRSGNWSERKSHRLPRLPKRHSHDDMMLLAQLSLPSSPSSLNEDSLSTTSELLSSRRARRIPKLVQRINSIYNAKRGKKRLKKLSLSSLETASLRDENSESESDSDDRFKAHTQRLVHIQSMLKRAPSYRTLELELLEWQERELFEYFVVVSLKKKPSRNTYLPEVSYQFPKLDRPTKQMREAEERLKAIPQFCFPDAKDWLPVSEYSSETFSFMLTGEDGSRRFGYCRRLLPNGKGPRLPEVYCVISRLGCFGLFSKVLDEVERRRGISAALVYPFMRSLMESPFPAPGKTIKVKTFLPGAGNEVLELRRPMDSRLEHVDFECLFTCLSVRQLIRIFASLLLERRVIFVADKLSTLSSCSHAVVALLYPFSWQHTFIPVLPASMIDIVCCPTPFLVGLLSSSLPKLKELPVEEALMVNLGSDRFIRQMDDEDTLLPRKLQAALEQALERKNELISQDSDSDSDDECNT-LNGLVSEVFIRFFVETVGHYSLFLTHSEKGERAFQREAFRKSVASKSIRRFLEVFMESQMFAGFIQDRELRKCRAKGLFEQRVEQYLEELPDTEQSGMNKFLRGLGNKMKFLHKKN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q924W7-1", "uniprot_id": "DEN2B_MOUSE", "id": "Q924W7-1", "name": "DENN domain-containing protein 2B", "aln": "---------------------------------------------------------------------------------MTMTANKNSSITHGTGGTKAPRETLSRSQSVSPPPVLYPPRSPIYP-LSDSE--TSACRYPSHSKSQVLLKDRHSRNPSLLG-QDPSPETSPPICTLKATSFSYLDRTPSLRK-----REDQKETVQGAVQDVEG--VAACLPLAQSTPFLG--AGSRSVLLSCTGTRAHSLGIREKISAWEGRREASPRMSLCGEKREGPGSEWSVSEGCPSVGCPSVVPSPCSSEKTFDFKGLRRMSRTFSECSYPETEEEAEALPGRDSLYRLEKRPGRTEPS-ALLRGHGIRKESSAVLSRIQKIEQALKEQPGRGLPQLPSSCYSVDQGRRKTGTLGTLEEPTGTASVSPSSRAGGVAGVAGEAGPPLDREGSASMKSETPGN-SSSPQLLPPKSSPDPAVNPVPKPKRTFEYEADKNPKTK-PSNGLPPSPTPAAPPPLPSTPAPPVTRRPKKDMRGHRKSQNRKSFEFEDASSLQSLYPSSPTENGTESQPKFGSKSTLEENAYEDIVGGLPKENPYEDVDLKNRRAGRKSQQLSENSLDSLHRMWSPQDRKYNHPPMQLSLKSNSQSLRSGNWSERKSHRLPRLPKRHSHDDMMLLAQLSLPSSPSSLNEDSLSTTSELLSSRRSRRIPKLVQRINSIYNAKRGKKRLKKLSMSSLETASLRDENSESESDSDDRFKAHTQRLVHIQSMLKRAPSYRTLELELLEWQERELFEYFVVVSLKKKPSRNTYLPEVSYQFPKLDRPTKQMREAEERLKAIPQFCFPDAKDWLPVSEYSSETFSFMLTGEDGSRRFGYCRRLLPSGKGPRLPEVYCVISRLGCFGLFSKVLDEVERRRGISAALVYPFMRSLMESPFPAPGKTIKVKTFLPGAGNEVLELRRPMDSRLEHVDFECLFTCLSVRQLIRIFASLLLERRVIFVADKLSTLSSCSHAVVALLYPFSWQHTFIPVLPASMIDIVCCPTPFLVGLLSSSLPKLKELPVEEALMVNLGSDRFIRQMDDEDTLLPRKLQAALEQALERKSELISQDSDSDSDDECNT-LNGLVSEVFIRFFVETVGHYSLFLTHSEKGERAFQREAFRKSVASKSIRRFLEVFMESQMFAGFIQDRELRKCRAKGLFEQRVEQYLEELPDTEQSGMNKFLRGLGNKMKFLHKKN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P78524-1", "uniprot_id": "DEN2B_HUMAN", "id": "P78524-1", "name": "DENN domain-containing protein 2B", "aln": "---------------------------------------------------------------------------------MTMTANKNSSITHGAGGTKAPRGTLSRSQSVSPPPVLSPPRSPIYP-LSDSE--TSACRYPSHSSSRVLLKDRHPPAPSPQNPQDPSPDTSPPTCPFKTASFGYLDRSPSACK-----RDAQKESVQGAAQDVAG--VAACLPLAQSTPFPGPAAGPRGVLLTRTGTRAHSLGIREKISAWEGRREASPRMSMCGEKREGSGSEWAASEGCPSLGCPSVVPSPCSSEKTFDFKGLRRMSRTFSECSYPETEEEGEALPVRDSFYRLEKRLGRSEPS-AFLRGHGSRKESSAVLSRIQKIEQVLKEQPGRGLPQLPSSCYSVDRGKRKTGTLGSLEEPAGGASVSAGSRAVGVAGVAGEAGPPPEREGSGSTKPGTPGN-SPSSQRLPSKSSLDPAVNPVPKPKRTFEYEADKNPKSK-PSNGLPPSPTPAAPPPLPSTPAPPVTRRPKKDMRGHRKSQSRKSFEFEDASSLQSLYPSSPTENGTENQPKFGSKSTLEENAYEDIVGDLPKENPYEDVDLKSRRAGRKSQQLSENSLDSLHRMWSPQDRKYNSPPTQLSLKPNSQSLRSGNWSERKSHRLPRLPKRHSHDDMLLLAQLSLPSSPSSLNEDSLSTTSELLSSRRARRIPKLVQRINSIYNAKRGKKRLKKLSMSSIETASLRDENSESESDSDDRFKAHTQRLVHIQSMLKRAPSYRTLELELLEWQERELFEYFVVVSLKKKPSRNTYLPEVSYQFPKLDRPTKQMREAEERLKAIPQFCFPDAKDWLPVSEYSSETFSFMLTGEDGSRRFGYCRRLLPSGKGPRLPEVYCVISRLGCFGLFSKVLDEVERRRGISAALVYPFMRSLMESPFPAPGKTIKVKTFLPGAGNEVLELRRPMDSRLEHVDFECLFTCLSVRQLIRIFASLLLERRVIFVADKLSTLSSCSHAVVALLYPFSWQHTFIPVLPASMIDIVCCPTPFLVGLLSSSLPKLKELPVEEALMVNLGSDRFIRQMDDEDTLLPRKLQAALEQALERKNELISQDSDSDSDDECNT-LNGLVSEVFIRFFVETVGHYSLFLTQSEKGERAFQREAFRKSVASKSIRRFLEVFMESQMFAGFIQDRELRKCRAKGLFEQRVEQYLEELPDTEQSGMNKFLRGLGNKMKFLHKKN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TY47-1", "uniprot_id": "A0AB32TY47_DANRE", "id": "A0AB32TY47-1", "name": "", "aln": "-----------------------------------------------------------------------------------MTANKSSKTAPRAGAAKGSQENSDRCQSVSPPPILTTGKEPVSSYLSGSEDTSQQGKYGKADAKLWTQKNWSCKTASLRSGASLSTDFECQSRLTKSRSISCLDKRLTIHKPPSGDRQDQKENQLQQTPPIGDGLNTGLLSLSTTSVGPSKLGHKRTFSLSHTGTCTSSIAIRKKISQWEGRKEALSRMSLCLEKRPGGGSE----------GCPSLLSSPCS-ETTFDFKGVRRMSTAFSECSYPETEED-EHTSDREAPIRFQKRPSKTESSGIFLRTFSARKETSAVLSRIQKIEQALKESPTSSPPQYLSNCYGLDKSRQKSFTISGTEDLDSTCGSKRSSICS--VATEPDVSPGSDRLFKLKQRFSISSTRSESPELPSAQDSPGITVNPLPKPKRTFEYDANRNHKSLLPGNGLPPS--TESPPPLPSTPAPAIVTNSKTDESKLKKTQDRESCESEDAVSLP----SSPTENGTVNHSRPSSKSTLEENAYEDIVE---KENPYEDVDPVRRCLARNSRLLPERSRDSLNRMWTSQERKSITPP-QLPSKPSSQSLRLPGPADRKSQRPSRLSKRHSHDDMLLLPQLGMPSSPCGLLDDSLNPSTDTLASHRQKRVPKVVLRINSIYCTKRGKKRLKKLSLSNIETASLRDDNSESESDSDDRFKAHTQRLLKLQSILRRAPSYRTLELQLIEWQERELFEYFVVVSLKKKPTKNSYAPEVTYQFPKLERLTKQMREAEQRLKAIPQFCFPDAKDWSPVSEYNSETFSFMLTGEDGSRRFGYCRRLLPSGKGPRLPEVYCVISRLGCFNLFSKILDEVERRRGISAALVYPFMRSVMESPFPAPGKTIKVKTFLPGAGNEVIELRRPMDSRLEHVDFESLFNCLSVRQVVRVFASLLLERRVIFVADKLSTLSSCVHAVVALLYPFSWQHTFIPVLPTSMVDIVCCPTPFLVGILSSSLPKLKELPVEEALMVDLGTDRFIRQMDDEASLLPRKLQAALEQSLEQRNDIINQDSDSESDEECSTSLNSVVSEAFIRFFLETIGHYSLFLTQGERGERIFQREPFRKSVASKSIRRFLGVFMESQMFAGFIQDREMRKCRAKGLFEQRVEQYLEELPDTEQSGVNKFLKGLGNKMKFLHKKN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *****.*. : :*.:*..: . .*.*******:* . :.*: . **.** :. :* . . . *: .* . . *.: . *: *:. **: : : *: *:*. . : . :. *.*: :: . . * . *: *** : .:.**:*** ****:** .**.:* *** * *** ****::.**** *.******:**** ::**********: * . *:: *::** .::*.* :** .. ***:************.***.* . ** *.**.:*:.::*: *:. *: . .. . .* . ... :..* :* . . : ... * *.: ..:.* . :***:*********:*::* *. *.****** . :**********.:. ..*.* :*:*.*:* * *** ** ******** .:.: .************** ********* * .*:*: *.*.* ***:***:.*:** ** **. *..***** . ::***:* .**.********:**.**.:****..* :***..::: *:*:* :*:**:* ****** :***********:*.:*******:*******************:::**:*:**********:*:********************::*:* ***:******:* ********:**************** *****.*************************.*******************.****:*********************:*************************:****************.**.******::*:*********************** *********************:**:************:*******************:**:********** :************:**::.::*.*****:**:**.* **.:***.*****:**:********:.*:*** ****.************** ****************:***************************:****:*************", "identical_positions": 720, "similar_positions": 240, "identity": "58.44%" }, { "cls_id": "homologset.agr.RGD:1308996", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P63083-1", "uniprot_id": "S10A5_RAT", "id": "P63083-1", "name": "Protein S100-A5", "aln": "-------METPLEKALTTMVTTFHKYSGREGSKLTLSRKELKELIKTELS--LAEKMKESSIDNLMKSLDKNSDQEIDFKEYSVFLTTLCMAYNDFFLE--------DNK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P63084-1", "uniprot_id": "S10A5_MOUSE", "id": "P63084-1", "name": "Protein S100-A5", "aln": "-------METPLEKALTTMVTTFHKYSGREGSKLTLSRKELKELIKTELS--LAEKMKESSIDNLMKSLDKNSDQEIDFKEYSVFLTTLCMAYNDFFLE--------DNK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P33763-1", "uniprot_id": "S10A5_HUMAN", "id": "P33763-1", "name": "Protein S100-A5", "aln": "-------METPLEKALTTMVTTFHKYSGREGSKLTLSRKELKELIKKELC--LGE-MKESSIDDLMKSLDKNSDQEIDFKEYSVFLTMLCMAYNDFFLE--------DNK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N4R7-1", "uniprot_id": "A0A8M1N4R7_DANRE", "id": "A0A8M1N4R7-1", "name": "Protein S100", "aln": "MSNLNSENASTLENAMQLMIQTFHKYSGNEGDKYTLSRQELKEMLTQELGNYLGNAQDKDAVDKVMGDLDSNNDGEVDFTEFIILVGALTVACNDFFLEYHEKDGKKDDKK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.**:*: *: *******.**.* ****:****::. ** *.: .:.::*.:* .**.*.* *:**.*: ::: * :* ****** *:* ", "identical_positions": 45, "similar_positions": 31, "identity": "40.54%" }, { "cls_id": "homologset.agr.RGD:1308998", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "M0R890-1", "uniprot_id": "M0R890_RAT", "id": "M0R890-1", "name": "", "aln": "MGSMKELS--VRQQTRVLLHKNLLKKWRMKRESLLEWSIPVVIGLYMGLFSYFKENNQVPEVPPQDLGSIDEFNGSSIMVVYTPISNVTQQIMNKTITAPTMKGTRIVGVPSEKDLDEMLLDHVPRAFGIVFNDTFFYKLKVYLMYGNPFLKEDLLAHCWDTYPHVFCSLTRYWKRGFVALQTAINAAIIEVTTKHPVMEELMSVNAFNMKTLPFISKDIFQYEIFILFCLLYFSSFIYFASRSVTKERKHSKEFMKVMGLQDSAFWLSWGLIYVGFIFIFSVFIAVIITSTRIIVMTGFLVIFTLFFLYGLSVIAVTFLMAVLLQKAIITNLFVFLFNLFWGCVGFTVLHKELPSSLEWVLSICSPFAFTSGMTKIIFLEYNLNGVVFPDPSGESYVMIAVFFILAFDGLLYLVLALYFDKILPCGADRRAAPLFFLNPVSCFRKRTSRNKVTERDIDPELPSDEYFEPVDPEYQGKEAIRIRNIRKEYKGKSGKVEALKGLFFDVYESQITAVLGHGGAGKSSLLNILNGLSVPTSGLATVYNKNLSEMQDLKEIRKMIGVCPQHNVQFDALTVKENLTLFANIKGIVPQSVAQEVQQILSELDMQTIQDELAEHLSEGQKRKLTFGVAILGDPRILLLDEPTAGLDPFSRQRVWGFLKERRADRVILFSTQFTDEADILADRKVILSNGALKCTGSSVFLKRKWGLGYHLSLFMNETCDSEQLTSFINHHIPGAKLKAKTKEKLVYTLPLEKTSKFPEFFSDLDKYSGQGLMNYEVSMSTLNEVFMNLEGEPSTTQDFEKGETLTDSDSLNEMEVAPPSLSKAQKTMSAMSLWRMQVCAIARLRVLKLRRERKAFLTFLPLLGISLIPLITEYMANALIEVKTNWEFKTDLYFLSPGQLPQGLRTSLLVINNTESNIEDFVQSLKHQNIVLEVDDFENRNATESLSYNGAIIVSGRQKDYRFSAVCNTKRLHCFPILMNVISNGILRMLNHTQHIRLEEDVLSSGIVVVWFGILEASLSILFIVCSVSPHIAMSSISDFKKKADSQLWISGLYPSAYWCGQALVDITLLSGILLTGYITLYTTKLMHIYLTGEIVLSIVLLAFGCAASLVFLTYVISFVFGKKRKNSGLWSICFFIVITIMFDTVLMDPFNEALLISAMMLVPSFSLNALLIVLEMRAYQYYREFGESKYGLSGVDLLLCLIPYFHTLLFIFVLRCLELKYGKNVVRKDPLFRIAPQSLHVQPNPEEPVDEDEDVQAERMRTSDALSTVNLDEKPAIIASCLHKEYTGQKKWCCSKRRKKIAVRNISFCVNKGEILGLLGPEGAGKSSSLRMIAGIMKPTAGEVELKELSSAVAHQGEGHGAAKLGYCPQENVLWPILTVKEHLEVYAAVKGLRKKDAVIAISRLVNAFKLHDQLNVQARNLVVGLTRKLCFALSILGNSPVLILDEPSTGLDVSGKQQMWQAIQAAVKDNKKGVLLSTHDLAEAEALCDRAAIMVSGRLRLIGSIQHLKRRFGKDYILELRVKEISQEPLVHKEILRLFPQAARQDRCFSLLTYKLPVTDVHPLSQAFHKLEAVKRGFNLDDYSLSQCTLDRVFLELSKEQELGDVHEEADITMRWKLLPPSDEL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K441-1", "uniprot_id": "ABCA6_MOUSE", "id": "Q8K441-1", "name": "ATP-binding cassette sub-family A member 6", "aln": "---MKELSVHVRQQTRALLHKILLKKWRRKRESLLEWSIPIIIGLHMGLFSYLARNIQVLEVPPQDLGSLNEFNGSSLVVVYTPISNITQQIMNKTTFAPTMKGTRIIGVPSIEDLDEVLLHNIPDALGVIFNDSFSYQLKVLRMYGNPFLKEDLLAHCWDTHSQAFCSLSKYWERGFVALQTAINAGIIEVTTNHSVMEELMSIDGINMKTLPFIPRDLSDYEIFILFCLLYFSSFIYFASSNVTKERKQCKEVMKVMGLQDSAFWLSWGLIYVGFIFIISIFIAIIITSTQIIMMTGFLVIFTLFFLYGLSLIAVTFLMAVLLQKAVLTNLIVLFFTLFWGCVGFTVLHKELPPSLEWVLSIFSPFAFTSGMAKVIFQDYNLNGVVFPDPSGESYVMIAVFFILAFDSLLYLVLALYFDKILLYGAEHRSAPLFFLNPTSCFRKTANRNKVIERDLDPELPSDEYFEPVDPEYQGKEAIRIRNIKKEYKGKSGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMQDLKEIRKAIGVCPQHNVQFDALTVKENLTLFAKIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQILLLDEPTVGLDPFSRQRIWGFLKERRADHVILFSTQFMDEADILADRKVLIANGALKCTGSSVFLKRKWGLGYHLSLFMDETCDSERLTSFINHHIPYAKLKAKTKEKLVYILPLERTSEFPEFFSDLDKYSGQGLMSYEVSMSTLNDVFLNLEGEPSTKQDFEKRETATDSESLNDMEVAYPSLSQVQETVSTMSLWRMQVCAIARLRILKLKRERKAFLIILLLLGIALLPLVIEYVANALLEVKNNWEFKTDLYFLSPGQLPQGLRTSLLVINNTESNIEDFLQSLKHQNIVLEVDDFENRNATNSLSYNGAIIVSGRQKDYRFSAVCNTKRLHCFPILMNVISNGILHMLNHTQYIRIKEDIFSPFIVLVWTGIQETCLFILCVICSLSPHIAMSSVSDYKKKADSQLWISGLYPSAYWCGQAVVDISLFSGMLLTSYFTSYTSKLLNIDMTSEIVFSVIVLALGCAASLVFLTYVISFVFGKRKKNSTLWSICFLLVIAITFEKVANGPFNEALVISATMLVPSFALNGLLVVLEMRAYQYYIEFEEIKHGLSAVDLLLCLIPYIHTLLFIFVLRCLELKYGKNVVRRDPIFRIAPQSLKAQPNPEEPIDEDENVQAERLRTSDALSTPNLDEKPVIIASCLHKEYAGQKKHCCSRRTRNMAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKRLSSAVGHQGDSR--AEFGYCPQENGLWPNLTVKEHLELYAAVKGLRKEDAVVAISRLVNALKLHDQLNVQVQNLVAGATRKLCFVLSILGNSPVLILDEPSTGLDVSGKHQVWQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRLRCIGPIQHLKRKFGQDYVLELRVKDVSQEPLVHREILKLFPQAARQDRCFSLLTYKLPVTDVHPLSQAFHKLEAVKHGFDLEDYSLSQCTLDRVILELSKEQELGTVYEEADMTLGRKLLPPSDEL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N139-1", "uniprot_id": "ABCA6_HUMAN", "id": "Q8N139-1", "name": "ATP-binding cassette sub-family A member 6", "aln": "-MNMKQKS--VYQQTKALLCKNFLKKWRMKRESLLEWGLSILLGLCIALFSSSMRNVQFPGMAPQNLGRVDKFNSSSLMVVYTPISNLTQQIMNKTALAPLLKGTSVIGAPNKTHMDEILLENLPYAMGIIFNETFSYKLIFFQGYNSPLWKEDFSAHCWDGYGEFSCTLTKYWNRGFVALQTAINTAIIEITTNHPVMEELMSVTAITMKTLPFITKNLLHNEMFILFFLLHFSPLVYFISLNVTKERKKSKNLMKMMGLQDSAFWLSWGLIYAGFIFIISIFVTIIITFTQIIVMTGFMVIFILFFLYGLSLVALVFLMSVLLKKAVLTNLVVFLLTLFWGCLGFTVFYEQLPSSLEWILNICSPFAFTTGMIQIIKLDYNLNGVIFPDPSGDSYTMIATFSMLLLDGLIYLLLALYFDKILPYGDERHYSPLFFLNSSSCFQHQRTNAKVIEKEIDAEHPSDDYFEPVAPEFQGKEAIRIRNVKKEYKGKSGKVEALKGLLFDIYEGQITAILGHSGAGKSSLLNILNGLSVPTEGSVTIYNKNLSEMQDLEEIRKITGVCPQFNVQFDILTVKENLSLFAKIKGIHLKEVEQEVQRILLELDMQNIQDNLAKHLSEGQKRKLTFGITILGDPQILLLDEPTTGLDPFSRDQVWSLLRERRADHVILFSTQSMDEADILADRKVIMSNGRLKCAGSSMFLKRRWGLGYHLSLHRNEICNPEQITSFITHHIPDAKLKTENKEKLVYTLPLERTNTFPDLFSDLDKCSDQGVTGYDISMSTLNEVFMKLEGQSTIEQDFEQVEMIRDSESLNEMELAHSSFSEMQTAVSDMGLWRMQVFAMARLRFLKLKRQTKVLLTLLLVFGIAIFPLIVENIMYAMLNEKIDWEFKNELYFLSPGQLPQEPRTSLLIINNTESNIEDFIKSLKHQNILLEVDDFENRNGTDGLSYNGAIIVSGKQKDYRFSVVCNTKRLHCFPILMNIISNGLLQMFNHTQHIRIESSPFPLSHIGLWTGLPDGSFFLFLVLCSISPYITMGSISDYKKNAKSQLWISGLYTSAYWCGQALVDVSFFILILLLMYLIFYIENMQYLLITSQIVFALVIVTPGYAASLVFFIYMISFIFRKRRKNSGLWSFYFFFASTIMFSITLINHFDLSILITTMVLVPSYTLLGFKTFLEVRDQEHYREFPEANFELSATDFLVCFIPYFQTLLFVFVLRCMELKCGKKRMRKDPVFRISPQSRDAKPNPEEPIDEDEDIQTERIRTATALTTSILDEKPVIIASCLHKEYAGQKKSCFSKRKKKIAARNISFCVQEGEILGLLGPNGAGKSSSIRMISGITKPTAGEVELKGCSSVLGH---------LGYCPQENVLWPMLTLREHLEVYAAVKGLRKADARLAIARLVSAFKLHEQLNVPVQKLTAGITRKLCFVLSLLGNSPVLLLDEPSTGIDPTGQQQMWQAIQAVVKNTERGVLLTTHNLAEAEALCDRVAIMVSGRLRCIGSIQHLKNKLGKDYILELKVKETSQVTLVHTEILKLFPQAAGQERYSSLLTYKLPVADVYPLSQTFHKLEAVKHNFNLEEYSLSQCTLEKVFLELSKEQEVGNFDEEIDTTMRWKLLPHSDEP", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **: * * ***:.** * :***** ********.:.:::** :.*** .* *. :.**:** :::**.**::********:******** ** :*** ::*.*. .:**:**.::* *:*::**::* *:* . *..*: ***: ***** : . *:*::**:***********:.***:**:*.*******: .:.*******.::: . *:**** **:**.::** * .******:.*:.**:****************.*****:*:*:::*** *:**:****:*** ********::*:.***:***:**::***.*:::.*****:****::::**.****:*.* ******:** ::* :******:******:**.***.* :* :*.*:**:********* * ::: :******. ***:: .. ** *:::*.* ***:***** **:**********::**********:*****::*:**.****:***.***********.** *** * .*:******:****:**** *****.***** *******:***:**** :.* ****:** *****.*:*:**:*************:: :***:********.*******:::*.:*:*****:******* ***********:::** ***:***:****:*********. :* *:.*::****.**** ****::.****** ****:*. **::****** *.**: .*::******:**::***:.: ****: * **:***:**:* .*:*: * ::* *.****** *:****.***:*: *.:* :* ::**:::**: * : *::: * :****.:*********** *****:***********::*******:**********.*:.***********:*******.***************:****:*:*:****:**::.. :. : :* *: : .: :: ::**:**:*:*.*:**:**:*.*********.********:**:::: :** *: * :: : :*.:**::::::: * ******: *:***:* *::*** ***: *::. :* *. . . *: :::*:: :****::* .: .**:* ::* ** * :. **..*:*:*:***::****:*****:*** **: :*:**:***:*** ..:******:****::*:**:**: **:* *****.**********:**** * *:* :::*.**:****::*********:*******:***:** *****:**** **.:.* :******* *** **::****:********* ** :**:***.*:***:**** .::*..* ******.**:*******:*******:* :*::*:******.**:.::****:**:**********.********* **.*****.::*:**:***:**: ** .*** ***:****** *:* *********:**:****:********:.*:*::********::*:********:* . ** * *: **** *** ", "identical_positions": 1021, "similar_positions": 417, "identity": "62.68%" }, { "cls_id": "homologset.agr.RGD:1308999", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LUX3-1", "uniprot_id": "A0ABK0LUX3_RAT", "id": "A0ABK0LUX3-1", "name": "Claudin", "aln": "MASTGLELLGMTLAVLGWLGTLVSCALPLWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTGQMQCKVYDSLLALPQDLQAARALCVVALLLALLGLLVAITGAQCTTCVEDEGAKARIVLTAGVLLLLSGILVLIPVCWTAHAIIQDFYNPLVAEALKRELGASLYLGWAAAALLMLGGGLLCCTCPPSHFERPRGPRLGYSIPSRSGASGLDKRDYV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O95484-1", "uniprot_id": "CLD9_HUMAN", "id": "O95484-1", "name": "Claudin-9", "aln": "MASTGLELLGMTLAVLGWLGTLVSCALPLWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTGQMQCKVYDSLLALPQDLQAARALCVIALLLALLGLLVAITGAQCTTCVEDEGAKARIVLTAGVILLLAGILVLIPVCWTAHAIIQDFYNPLVAEALKRELGASLYLGWAAAALLMLGGGLLCCTCPPPQVERPRGPRLGYSIPSRSGASGLDKRDYV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*************************************************************************************:*************************************:***:***********************************************************.:.***************************", "identical_positions": 211, "similar_positions": 6, "identity": "97.24%" }, { "cls_id": "homologset.agr.RGD:1309000", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JTZ2-1", "uniprot_id": "SOX6_RAT", "id": "A0A0G2JTZ2-1", "name": "Transcription factor SOX-6", "aln": "-----------------MSSKQATSPFACTVDG-EETMTQDLTSREKEEGSDQHPASHLPLHPIMHNKPHSEELPTLVSTIQQDADWDSVLSSQQRMESENNKLCSLYSFRNTSTSPHKPDEGSRER-EIMNSVTFGTPERRKGSLADVVDTLKQKKLEEMTRTEQEDSSCMEKLLSKDWKEKMERLNTSELLGEIKGTPESLAEKERQLSTMITQLISLREQLLAAHDEQKKLAASQIEKQRQQMDLARQQQEQIARQQQQLLQQQHKINLLQQQIQ-VQGHMPPLMIPIFPHDQRTLAAAAAAQQGFLFPPGITYKPGDNYPVQFIPSTMAAAAASGLSPLQLQKGHVSHPQINPRLKGISDRLGRNLDPYEHGGGHSYNHKQIEQLYAAQLASMQVSPGAKMPSTPQPPNSAGAVSPTGIKNEKRGTSPVTQVKDETTAQPLNLSSRPKTAEPVKSPTSPTQSLFPASKTSPVNLPNKSSIPSPIGGSLGRGSSLDILSSLNSPALFGDQDTVMKAIQEARKMREQIQREQQQQ-PHGVDGKLSSMNSMGLSNCRNEKERTRFENLGPQLTGKSSEDGKLGPGVIDLTRPEDAEGSKAMNGSAAKLQQYYCWPTGGATVAEARVYRDARGRASSEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSKIHLEKYPNYKYKPRPKRTCIVDGKKLRIGEYKQLMRSRRQEMRQFFTVGQQP--QIPITTGTGVVYPGAITMATTTPSPQMTSDCSSTSASPEPSLPVIQSTYGMKMDGASLAGNDMINGEDEMEAYDDYEDDPKSDYSSENEAPEPVSAN--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P40645-1", "uniprot_id": "SOX6_MOUSE", "id": "P40645-1", "name": "Transcription factor SOX-6", "aln": "-----------------MSSKQATSPFACTADG-EEAMTQDLTSREKEEGSDQHPASHLPLHPIMHNKPHSEELPTLVSTIQQDADWDSVLSSQQRMESENNKLCSLYSFRNTSTSPHKPDEGSRER-EIMNSVTFGTPERRKGSLADVVDTLKQKKLEEMTRTEQEDSSCMEKLLSKDWKEKMERLNTSELLGEIKGTPESLAEKERQLSTMITQLISLREQLLAAHDEQKKLAASQIEKQRQQMDLARQQQEQIARQQQQLLQQQHKINLLQQQIQ-VQGHMPPLMIPIFPHDQRTLAAAAAAQQGFLFPPGITYKPGDNYPVQFIPSTMAAAAASGLSPLQLQKGHVSHPQINPRLKGISDRFGRNLDPSEHGGGHSYNHRQIEQLYAAQLASMQVSPGAKMPSTPQPPNSAGAVSPTGIKNEKRGTSPVTQVKDETTAQPLNLSSRPKTAEPVKSPTSPTQNLFPASKTSPVNLPNKSSIPSPIGGSLGRGSSLDILSSLNSPALFGDQDTVMKAIQEARKMREQIQREQQQQ-PHGVDGKLSSMNNMGLSNCRTEKERTRFENLGPQLTGKSSEDGKLGPGVIDLTRPEDAEGSKAMNGSAAKLQQYYCWPTGGATVAEARVYRDARGRASSEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSKIHLEKYPNYKYKPRPKRTCIVDGKKLRIGEYKQLMRSRRQEMRQFFTVGQQP--QMPITTGTGVVYPGAITMATTTPSPQMTSDCSSTSASPEPSLPVIQSTYGMKMDGASLAGNDMINGEDEMEAYDDYEDDPKSDYSSENEAPEPVSAN--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P35712-1", "uniprot_id": "SOX6_HUMAN", "id": "P35712-1", "name": "Transcription factor SOX-6", "aln": "-----------------MSSKQATSPFACAADG-EDAMTQDLTSREKEEGSDQHVASHLPLHPIMHNKPHSEELPTLVSTIQQDADWDSVLSSQQRMESENNKLCSLYSFRNTSTSPHKPDEGSRDR-EIMTSVTFGTPERRKGSLADVVDTLKQKKLEEMTRTEQEDSSCMEKLLSKDWKEKMERLNTSELLGEIKGTPESLAEKERQLSTMITQLISLREQLLAAHDEQKKLAASQIEKQRQQMDLARQQQEQIARQQQQLLQQQHKINLLQQQIQ-VQGHMPPLMIPIFPHDQRTLAAAAAAQQGFLFPPGITYKPGDNYPVQFIPSTMAAAAASGLSPLQLQKGHVSHPQINQRLKGLSDRFGRNLDTFEHGGGHSYNHKQIEQLYAAQLASMQVSPGAKMPSTPQPPNTAGTVSPTGIKNEKRGTSPVTQVKDEAAAQPLNLSSRPKTAEPVKSPTSPTQNLFPASKTSPVNLPNKSSIPSPIGGSLGRGSSLDILSSLNSPALFGDQDTVMKAIQEARKMREQIQREQQQQQPHGVDGKLSSINNMGLNSCRNEKERTRFENLGPQLTGKSNEDGKLGPGVIDLTRPEDAEGSKAMNGSAAKLQQYYCWPTGGATVAEARVYRDARGRASSEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSKIHLEKYPNYKYKPRPKRTCIVDGKKLRIGEYKQLMRSRRQEMRQFFTVGQQP--QIPITTGTGVVYPGAITMATTTPSPQMTSDCSSTSASPEPSLPVIQSTYGMKTDGGSLAGNEMINGEDEMEMYDDYEDDPKSDYSSENEAPEAVSAN--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TT03-1", "uniprot_id": "A0AB32TT03_DANRE", "id": "A0AB32TT03-1", "name": "", "aln": "MLNMEGFLRSSFLLSRIMSSKQATSPFTSTPDGGEDGVNQERMPWEKEENSESLVAPQLPLHNLLHNKPPLEELQPISSSVPPESDWDSLMSAQQRMESDSNKVCSLYSFRNNSTSPHKPEEGARERGDLLSSSAFGTPERRKGSLADVVDTLKQKKLEEMTKTEQDESSCMEKLLSKDWKEKMERLNTGELLGEIKGTPESLAEKERQLSTMITQLISLREQLLAAHDEQKKLAASQMEKQRQQMELARQQQEQIARQQQQLLQQQHKINLLQQQIQQVQGHMPPLMIPIFPHDQRTLAAAAAAQQGFLFPPGMSYKPGDNYPVQFIPSTMAAAAASGLNPLQLQ-----------------------------------------QLYAAQLASMQVSPGAKMPPLPQPPNSAGQISPSGLKNEKRSSTPLAQVKEEG-TQPLNLSARPKTAEPIKSPTSPTQSLFPGSKSSPNSLSKSGDIPSPIGG-LGRGSSLDILSSLNSTALFGDQDAVMKAIQEARKMREQIQREQLQHHQQGMEVKLSALTSMGLNNCRTEKERSHYDNLGHHLS-KLGEDGKIGHRVIDLTRPEDFEGCRELNGCADKPHQYYCWPTGGASTTEARVYREPRGRNSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMTNQEKQPYYEEQARLSKIHLEKYPNYKYKPRPKRTCIIDGKKLRISEYKQMMRSRRQEMRQFFTVGQQPQTQIPITTSAGVVYPGAITMATTTPSPHMTSDCSSASASPEPTIPVIQSTFNMKMEPGTMVPSDAVNGEDEMDMYEDFEDEPKSDYSSENDTHEPVSAN--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q59DN5-1", "uniprot_id": "Q59DN5_DROME", "id": "Q59DN5-1", "name": "", "aln": "---------------------------------------MKPPGEDQTNEKEHSDLGMIKQLQLIRNRILSQAHYDSMTDIDASAQQQQQLQNVQRLQHES----CLQELHNHLSSQYG-----------------------------AVRFTAANPQHQNQQAVSVSSGNLMPFLPAFLQPPMP--NAQQLLQLIPGHENAQSVPTHHHSHPQSEAFSTHKMALAPMWSTAAVAAAHIQAALAAAAVAAANNN---KNSSHFSNNTNIVGLATRGNE---------LLNTDSDPQMEIGETRRGGNGGSCRSRPESPTYENPPYEILSYSHNTPPES--------------------------------------------------------------------PHGRTADCSKNFSPSPTDN--LSIASVSEAQDSEMDAPLNLSK--PKGSPSSSPNSSSQ----------------------------RDHCENLTPVVSSPPLSWHQGQPHYAEIELPLLKSHG-RVWNSAVACSGGSRATRVSRDSVNSCGTNSERS------AALDPESLNSGQLGPVPASPSSQPLRQGNGHGHG-------------------------GNHGHVHSKPHIKRPMNAFMVWAKDERRKILKACPDMHNSNISKILGARWKAMSNADKQPYYEEQSRLSKLHMEQHPDYRYRPRPKRTCIVDGKKMRISEYKVLMRNRRAEMRQLWCR-------------TGGVSGGSGSLCADACP---KGSGGSNSQVAVAAAAAVYHLQDMASSAASTAHGHDCGHTPPQQFFYPPESLSPSGFSSDEVELASQRELDD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :: : .: : :::*: : : : .:: :. :. **:: :. .* .::* :* : .* : .: :: . .*. : :*. : * *: :** * * :: : :: * :: :* :: **. . :**:::: :* ::: ::..:: :: : :.* : : :: .. * :. : . :* . . :* * :::. : :.. * . :..: : .**: .* . :.:::.::. ***** ...* .**.*.:* *. . :: . :.*..* .*. * * ::.: * . . : : :. .:..* .:.**: * : :.*::* . : :* :* :*: .:**********************:* *************:***:*:* :********:****:*:*::*:*:*:********:****:**.*** :**.** ****:: :* * *: ::.: : . ... .* * . .: ..: .* . .: . .. . : : *. . *.:**:: . ", "identical_positions": 150, "similar_positions": 223, "identity": "17.61%" }, { "cls_id": "homologset.agr.RGD:1309003", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P57080-1", "uniprot_id": "UBP25_MOUSE", "id": "P57080-1", "name": "Ubiquitin carboxyl-terminal hydrolase 25", "aln": "MTVEQNVLQQSAAQKHQQTFLNQLREITG----INDAQILQQALKDSNG-----------------------------NLELAVAFLTAKNAKTPPQ---------EETGYYQT--------ALPGNDRYISVGSQADANVIDLTGDDKDDLQRAIALSLAESNRAFRETGITDEEQAISRVLEASIAENKACLKRTP-IEVWRDSRNPYDRKRQEKAPVGLKNVGNTCWFSAVIQSLFNLLEFRRLVLNYKPPSNAQDLPRNQKEHRNLPFMRELRYLFALLVGTKRKYVD-----PSRAVEILKDAFKSNDSQQQDVSEFTHKLLDWLEDAFQMKAEEETDEEKPKNPMVELFYGRFLAMGVLEGKKFENTEMFGQYPLQVNGFKDLHECLEAAMIEGEIESLHS-DNSGKSGQEHWFTELPPVLTFELSRFEFNQALGRPEKIHNKLEFPQVLYLDRYMHRNRE-ITRIKREEIKRLKDYLTVLQQRLERYLSYGSGPKR-----------FPLVDVLQYALEFASSKPVCTSPVDDIDASSSASGPLPSQSLPSTT-EQQGPCASDLPGSSSPASGAALPLRSVIHKPFTQSRIPPDLPMHPAPRHITEEELCVLESCLHRWRTEIENDTRDLQESISRIHRTIELMYSDKSMIQVPYRLHAVLVHEGQANAGHYWAYIFDHRESRWMKYNDIAVTKSSWEELVRDSFG--------------------------------GYRNASAYCLMYIDDKAQFLIQEEFNKETG----------QALVGMETLPPDLR---DFVEEDNQRFEKELEEWDTQLAQRSLQEKLLAAPKLREAEAS-----------------ATTAQAGG-ADYLEQPSRSDLSKHWKEETLRVIAKASHDLEDKGPETVLQS------------------------------------------------------------------------------------------AIKLEYSRLVKLAQEDTPPETDYRLHHVLVYFIQNQAPKKIIEKTLLEQFGDRNLSFDERCHNIMKVAQAKLEMIKPEEVNLEEY-EEWHADYKKFRETTMYLITGLENFQ----------RESYIDSLLFLLCAYQNNKELLSK---GPYRGHDGELISHYRRECLLKLNEQAAELFESGEDGDVNNGLIIMNEFIVPFLPLLLVDDMEEKDILAVEDMRNRWCSYLGQEMEANLQEKLTDFLPKLLDCSTEIKGFHEPPKLPSYSAHELCERFARIMLSLS--RTPADGR---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZPF8-1", "uniprot_id": "A0A8I5ZPF8_RAT", "id": "A0A8I5ZPF8-1", "name": "Ubiquitin carboxyl-terminal hydrolase 25", "aln": "MTVEQNVLQQSAAQKHQQTFLNQLREITG----INDAQILQQALKDSNG-----------------------------NLELAVAFLTAKNAKTPPQ---------EETAYYQTA-------ALPGSDRYISVGSQADANVIDLTGDDKDDLQRAIALSLAESNRTFRETGITDEEQAISRVLEASIAENKACLKRTP-IEVWRDSRNPYDRKRQDKAPVGLKNVGNTCWFSAVIQSLFNLLEFRRLVLNYKPPSNAQDLPRNQKEHRNLPFMRELRYLFALLVGTKRKYVD-----PSRAVEILKDAFKSNDSQQQDVSEFTHKLLDWLEDAFQMKAEEETDEEKPKNPMVELFYGRFLAMGVLEGKKFENTEMFGQYPLQVNGFKDLHECLEAAMIEGEIESLHS-DNSGKSGQEHWFTELPPVLTFELSRFEFNQALGRPEKIHNKLEFPQVLYLDRYMHRNRE-ITRIKREEIKRLKDYLTVLQQRLERYLSYGSGPKR-----------FPLVDVLQYALEFASSKPVCTSPVDDIDATSSTSGSTSSQSLPSTT-EQQGTPASDLP-SSSPASGAALSLRSVIHKPFTQSRIPPDLPMHPAPRHITEEELSVLESCLHRWRTEIENDTRDLQESISRIHRTIELMYSDKSMIQVPYRLHAVLVHEGQANAGHYWAYIFDHRESRWMKYNDIAVTKSSWEELVRDSFG--------------------------------GYRNASAYCLMYINDKAQFLIQEEFNKETG----------QALVGMETLPPDLR---DFVEEDNQRFEKELEDWDTQLAQRALQEKLLAAQKLREAESS-----------------APTAQAGG-PDYLEQPSRSDLSKHWKEETLRVIAKASHDHEDKGPETVLQSKP--------------------ENTTSQPPSKQQAVEVQIPHIGKFMIESKEGGYDDEIMMTPSMQGIIMAIGKSRSVYDRCGPEAGFFKAIKLEYSRLVKLAQEDTPPETDYRLHHVLVYFIQNQAPKKIIEKTLLEQFGDRNLSFDERCHNIMKVAQAKLEMIKPEEVNLEEY-EEWHADYKKFRETTMYLIIGLENFQ----------RESYIDSLLFLICAYQNNKELLSK---GPYRGHDGDLISHYRRECLLKLNEQAAELFESGEDREVSNGLIIMNEFIVPFLPLLLVDETEERDILAVEDMRNRWCSYLGQDMEPNLQEKLTDFLPKLLDCSTEIKGFHEPPKLPSYSAHELCERFARIMLSLS--RTPADGR---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UHP3-2", "uniprot_id": "UBP25_HUMAN", "id": "Q9UHP3-2", "name": "Ubiquitin carboxyl-terminal hydrolase 25", "aln": "MTVEQNVLQQSAAQKHQQTFLNQLREITG----INDTQILQQALKDSNG-----------------------------NLELAVAFLTAKNAKTPQQ---------EETTYYQT--------ALPGNDRYISVGSQADTNVIDLTGDDKDDLQRAIALSLAESNRAFRETGITDEEQAISRVLEASIAENKACLKRTP-TEVWRDSRNPYDRKRQDKAPVGLKNVGNTCWFSAVIQSLFNLLEFRRLVLNYKPPSNAQDLPRNQKEHRNLPFMRELRYLFALLVGTKRKYVD-----PSRAVEILKDAFKSNDSQQQDVSEFTHKLLDWLEDAFQMKAEEETDEEKPKNPMVELFYGRFLAVGVLEGKKFENTEMFGQYPLQVNGFKDLHECLEAAMIEGEIESLHS-ENSGKSGQEHWFTELPPVLTFELSRFEFNQALGRPEKIHNKLEFPQVLYLDRYMHRNRE-ITRIKREEIKRLKDYLTVLQQRLERYLSYGSGPKR-----------FPLVDVLQYALEFASSKPVCTSPVDDIDASSPPSGSIPSQTLPSTT-EQQGALSSELP-STSPSSVAAISSRSVIHKPFTQSRIPPDLPMHPAPRHITEEELSVLESCLHRWRTEIENDTRDLQESISRIHRTIELMYSDKSMIQVPYRLHAVLVHEGQANAGHYWAYIFDHRESRWMKYNDIAVTKSSWEELVRDSFG--------------------------------GYRNASAYCLMYINDKAQFLIQEEFNKETG----------QPLVGIETLPPDLR---DFVEEDNQRFEKELEEWDAQLAQKALQEKLLASQKLRESETS-----------------VTTAQAAGDPEYLEQPSRSDFSKHLKEETIQIITKASHEHEDKSPETVLQS------------------------------------------------------------------------------------------AIKLEYARLVKLAQEDTPPETDYRLHHVVVYFIQNQAPKKIIEKTLLEQFGDRNLSFDERCHNIMKVAQAKLEMIKPEEVNLEEY-EEWHQDYRKFRETTMYLIIGLENFQ----------RESYIDSLLFLICAYQNNKELLSK---GLYRGHDEELISHYRRECLLKLNEQAAELFESGEDREVNNGLIIMNEFIVPFLPLLLVDEMEEKDILAVEDMRNRWCSYLGQEMEPHLQEKLTDFLPKLLDCSMEIKSFHEPPKLPSYSTHELCERFARIMLSLS--RTPADGR---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B6G9-1", "uniprot_id": "A0A8M3B6G9_DANRE", "id": "A0A8M3B6G9-1", "name": "Ubiquitin carboxyl-terminal hydrolase 25", "aln": "MTVEQNVLQQHS-QKHQQTLLNQLREVTG----TTDVQLLQQALQVSNG-----------------------------DLVEAVAFLTEKNAKVPQQ---------DEATYYQT--------AQITNDRYISVGSQADTNVIDLTGDDKDDLQRAIALSLEESNRAFRETGITDEEQAISRVLEASIAENKASLKRTH-TEVWSDSPNPHERKRMENCPVGLKNVGNTCWFSAVIQSLFNLLEFQRLVLHYSPPARMQDLPRNQKEHRNLPFMQELRHLFSLLVGSKRKYVD-----PSGAVEILKDAFKSSESQQQDVSEFTHKLLDWLEDAFQIKAEEDREGEKPKNPMVELFYGRFLAVGVLEGKKFENTEMFGQYPLQVNGFKDLHECLEAAMIEGEIESLHSAENSAKSGQEHWFTELPPVLTFELSRFEFNQALGRPEKIHNKLEFPSMLYMDRYMDRNRE-ITRIKREEIRRLKEHLTVLQQRLERYLSYGSGPKR-----------FPLADVLQYAMEFASSKPVCTSPVEDIDTTAPPGGTIAQLPPPASAGEQPDACVSAEGSGSGLQASQQQQQRVSIHKPFTQSRVPPDLPMHPAPRHITEEELRVLESCLHRWRSEVENDTRDLQASISRIHRTIELMYSDKSMMQVPYRLHAVLVHEGQANAGHYWAYIYDRHHQRWMKYNDIAVTKSSWEELVRDSFG--------------------------------GYRNASAYCLMYIDDKKPFLIQEEFDKETG----------QMLSGLDKLPPDLK---VFVEADNKLFEREMEEWDALQARKLQQEKLALAAAAAAAAAASVAVQPMSTEPCSPDNTAPSAAPQHDPEYMEQQSPSGDSKHLQEDTERAISKAAAEHDEKSPEALLNTSQSSHPDSKLTSDPCPPPDPEQDDPTCPPPGPQRVVEVAIPNVGTFVIQSKEGGYDDEAMMTPNMQGIIMAIGKSRSVYDKCGPEAAFFKAMKVEYTRLLRLAQEDTPPERDYRLQHVIVFFIHNEAPKKIVERTLLMQFADRNLGFDERCKSIMKVARAKLELIKPDEVNMEEY-EMWHQDYRIFRETSVFLLIGLELFM----------KKSFVEALMYLIYAYQYNKELLAK---GPYRGHDEELIAHYRRECLLKLNEYAAALFETGEEAKVNTGLSIMNDLVVPCLPLLLVDEMEEKDMVAVEDMRNRWCSYLGQEMEPNLQEKLTDFLPKLLDCSTEIKSFHEPPKLPSYSTLELFERFGRVMTSLTMGRTPADGR---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q01476-1", "uniprot_id": "UBP2_YEAST", "id": "Q01476-1", "name": "Ubiquitin carboxyl-terminal hydrolase 2", "aln": "MPNEDNELQKAIENHHNQLLNQDKENADRNGSVIEDLPLYGTSINQQSTPGDVDDGKHLLYPDIATNLPLKTSDRLLDDILCDTIFLNSTDPKVMQKGLQSRGILKESMLSYSTFRSSIRPNCLGSLTDQVVFQTKSEYDSISCPKYNKIHVFQAVIFNPSLAEQQISTFDDIVKIPIYHLKVSVKVRQELERLKKHVGVTQFHSLDHLHEYDRVDLSTFDSSDPNLLDYGIYVSDDTNKLILIEIFKPEFNSPEEHESFTADAIKKRYNAMCVKNESLDKSETPSQVDCFYTLFKIFKGPLTRKSKAEPTKTIDSGNLALNTHLNPEWLTSKYGFQASSEIDEETNEIFTEYVPPDMVDYVNDLETRKIRESFVRKCLQLIFWGQLSTSLLAPNSPLKNTKSVKGMSSLQTSFSTLPWFHLLGESRARILLNSNEQTHSPLDAEPHFINLSVSHYYTDRDIIRNYESLSSLDPENIGLYFDALTYIANRKGAYQLIAYCGKQDIIGQEALENALLMFKINPKECNISELNEATLLSIYKYETSNKSQVTSNHLTNLKNALRLLAKYTKSDKLKFYVDHEPYRALSQAYDTLSIDESVDEDIIKTAYSVKINDSPGLKLDCDRALYTIAISKRSLDLFNFLTEECPQFSNYYGPE-KLDYQEALKLLQVNENASDETILKIFKQKWFDENVYEPDQFLILRAALTKISIERNSTLITNFLLTGTIDPNSLPPENWPTGINNIGNTCYLNSLLQYYFSIAPLRRYVLEYQKTVENFNDHLSNSGHIRRIGGREISRGEVERSIQFIYQLRNLFYAMVHTRERCVTPSKELAYLAFAPSNVEVEFEVEG-------------NKVVDQTGVLSDSKKETTDDAFTTKIKDTSLIDLEMEDGLNGDVGTDANRKKNESN-----------------DAEVSENEDTTGLTSPTRVAKISSDQLENALEMGRQQDVTECIGNVLFQIESGSEPIRYDEDNEQYDLVKQLFYGTTKQSIVPLSATNKVRTKVERFLSLLINIGDHPKDIYDAFDSYFKDEYLTMEEYGDVIRTVAVTTFPTILQVQIQRVYYDRERLMPFKSIEPLPFKEVIYMDRYADTENPLLLAKKKETEEMKQKLKVMKNRQRELLSRDDSGLTRKDAFLESIKLLESDTIKKTPLKIEAANDVIKTLRNNVQNIDNELMKLYNDINSLEEKISHQFDDFKEYGYSLFSVFIHRGEASYGHYWIYIKDRNRNGIWRKYNDETISEVQEEEVFNFNEGNTATPYFLVYVKQGQEGDIEPLKRILK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. *:* **: ::*:* : :: .: * : ::: .. :: . **. .:.*. : :. *.* . : . :::: : *. . :* .: :*: :. ::: : . : :...: :: **: : . : :: .* : .... .: . : * :. :*: :. : .:..* . :.:. : ::* .: : . * . :: . . . .: ..* :. :. ::: ** :** . : ::*..: : *. : : . . :. ** :*:.:: : * . * . : ::. . . . . . ** * : * . : : : * . * ** : ** * :: :. *:* : ** : :* * . *: : : .: :::. : . .: . ::: . . . .: . . .. :. : *: . . :*.:. *:. : :.: : ** ::. :. *. : :: *: : *:*. :: : . ... : ::: : ::: :: : . * *: : * :::: : *. : : * : ::. *: .: * :. : : * : . .: :: : . :.: :: : : : ..:: :. . : :. .:. : ::.:.: :*: * : :: * *. * ::* . * .** :.: * ::: * . :: :. .. : :: : ::. : * : ::***:: * * . : .. :* . : . .. * *::: : ::: .::: .:: * : : *. . : : : . . . .:: . .. :: * * : :* ", "identical_positions": 96, "similar_positions": 376, "identity": "7.37%" }, { "cls_id": "homologset.agr.RGD:1309004", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZCK0-1", "uniprot_id": "D3ZCK0_RAT", "id": "D3ZCK0-1", "name": "Zinc finger protein 307", "aln": "MAREPGACAALNAPSAEEGTGFLVVKVEPEEASQLAEEPSWLGSP--GPDRSRQRFRAFRYPDAAGPRQALSRLRELCRQWLRPDMHSKEQILELLVLEQFLTILPGELQAWVREQHPDSGEEVVALLEYLDRQLDETPPQVPTGEWSRELLCCKVALVTSSQDSQSSHSQAMKSLFKHESQES----------------------------------------------------LECS--------------PLQARGLEMKPETRGLPLAEEYKEQKPEQTVWFLGEDTVQISTSTEASEQEGKLQTTQKNATGNRRFYCHECGKSFAQSSGLTKHKRIHTGEKPYECEDCGKTFIGSSALVIHQRVHTGEKPYECEECGKVFSHSSNLIKHQRTHTGEKPYECDDCGKTFTQSCSLLEHHKIHTGEKPFQCNLCGKAFRRSSHLLRHQRIHGDKAAPKLLHGETWEGQSRVASLGDIVEAPETYQCNECERSFTRSRSLIEHKKIHTGEKPYQCDACGKGFTRTSYLVQHRRSHVGKKLSHSDL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5SZT6-1", "uniprot_id": "Q5SZT6_MOUSE", "id": "Q5SZT6-1", "name": "", "aln": "MAREPGTSAALNARSAEEGTGLLVVKVEQEEASPLAEETSWLGSP--GPDRSRQRFRAFRYPEAAGPRQALSRLRELCRQWLRPDMHSKEQILELLVLEQFLTILPGELQTWVREQHPDSGEEVVALLEYLDRQLDDTPPQVSTGEWSRELLCCKVAVVTPSQDSQSSHCQAMKSLFKHESQES----------------------------------------------------LECS--------------PLQARGLEMKPETRDLPRAEEYRDQKPEQTVCFLGEDTVPIPTGAEASEQEGKLQTAQKSATGTRRHFCCECGKSFAQSSGLTKHKRIHTGEKPYECEDCGKTFIGSSALVIHQRVHTGEKPYECEECGKVFSHSSNLIKHQRTHTGEKPYECDDCGKTFTQSCSLLEHHKIHTGEKPFQCNLCGKAFRRSSHLLRHQRIHGDKTAPKPLHGEAWEGQSPVAGQGEDVEAPETYQCSECERSFTRRRSLLEHKKIHTGEKPYQCDACGKGFTRTSYLAQHQRSHVGKKLSHSDL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q969J2-1", "uniprot_id": "ZKSC4_HUMAN", "id": "Q969J2-1", "name": "Zinc finger protein with KRAB and SCAN domains 4", "aln": "MAREPRKNAALDAQSAEDQTGLLTVKVEKEEASALTAEVRAPCSPARGPERSRQRFRGFRYPEAAGPREALSRLRELCGQWLQPEMHSKEQILELLVLEQFLTILPGNLQSWVREQHPESGEEVVVLLEYLERQLDEPAPQVPVGDQGQELLCCKMALLTQTQGSQSSQCQPMKALFKHESLGSQPLHDRVLQVPGLAQGGCCREDAMVASRLTPGSQGLLKMEDVALTLTPGWTQLDSSQVNLYRDEKQENHSSLVSLGGEIQTKSRDLPPVKKLPE-KEHGKICHLREDIAQIPTHAEAGEQEGRLQRKQKNAIGSRRHYCHECGKSFAQSSGLTKHRRIHTGEKPYECEDCGKTFIGSSALVIHQRVHTGEKPYECEECGKVFSHSSNLIKHQRTHTGEKPYECDDCGKTFSQSCSLLEHHKIHTGEKPYQCNMCGKAFRRNSHLLRHQRIHGDKNVQNPEHGESWESQGRTESQWENTEAPVSYKCNECERSFTRNRSLIEHQKIHTGEKPYQCDTCGKGFTRTSYLVQHQRSHVGKKTLSQ--", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***** ***:* ***: **:*.**** **** *: * ** **:*******.****:*****:********* ***:*:**********************:**:*******:******.*****:****:..***..*: .:******:*::* :*.****:.*.**:****** * *:.* .* : * *::.::*.** .:: : * . .: .* ** . *.* :**.****:** **.* *.**.:* ***************:**************************************************************************:*****************:***:*******.************* . : ***:**.*. . . : .*** :*:*.******** ***:**:************:***********.**:******* . ", "identical_positions": 345, "similar_positions": 83, "identity": "62.96%" }, { "cls_id": "homologset.agr.RGD:1309005", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4A5X7-1", "uniprot_id": "D4A5X7_RAT", "id": "D4A5X7-1", "name": "Ganglioside-induced differentiation-associated protein 1", "aln": "MTSQGPLPTRQHSFLGVKLHLPEASSSAKHVLYATGGPAKPKDGSKPLQQAGQPTRLAESLHPAMARKQDEARSGVP--LRAQGPPAAEVRLILYHWTHSFSSQKVRLVIAEKALKCEEHDVSLPLSEHNEPWFMRLNSTGEVPVLIHGENIICEATQIIDYLEQTFLDERTPRLMPDEGSMYYPRVQHYRELLDSLPMDAYTHGCILHPELTVDSMIPAYATTRIRGQIGNTESELKKLAEENPDLQEAYIAKQKRLKSKLLDHDNVKYLKKILDELEKVLDQVETELQRRNEETPDEG-NQPWLCGESFTLADVSLAVTLHRLKFLGFARRNWGHGKRPNLESYYERVLKRKTFNKVLGHVNNILISAVLPTAFRVAKKRAPKVLGSTLVVGLLVGMGYFAFMLFRRRLGNMILSLRPRPNYF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88741-1", "uniprot_id": "GDAP1_MOUSE", "id": "O88741-1", "name": "Ganglioside-induced differentiation-associated protein 1", "aln": "----------------------------------------------------------------MARRQDEARAGVP--LRVEGPPDKEVHLILYHWTHSFSSQKVRLVIAEKALKCEEHDVSLPLSEHNEPWFMRLNSAGEVPVLVHGENIICEATQIIDYLEQTFLDERTPRLMPDEGSMYYPRVQHYRELLDSLPMDAYTHGCILHPELTVDSMIPAYATTRIRSQIGNTESELKKLAEENPDLQEAYIAKQKRLKSKLLDHDNVKYLKKILDELEKVLDQVETELQRRNEETPEEG-NQPWLCGESFTLADVSLAVTLHRLKFLGFARRNWGHGKRPNLETYYERVLKRKTFNKVLGHVNNILISAVLPTAFRVAKKRAPKVLGSTLVVGLLVGMGYFAFMLFRRRLGSMILALRPRPNYF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TB36-1", "uniprot_id": "GDAP1_HUMAN", "id": "Q8TB36-1", "name": "Ganglioside-induced differentiation-associated protein 1", "aln": "----------------------------------------------------------------MAERQEEQRGSPP--LRAEGKADAEVKLILYHWTHSFSSQKVRLVIAEKALKCEEHDVSLPLSEHNEPWFMRLNSTGEVPVLIHGENIICEATQIIDYLEQTFLDERTPRLMPDKESMYYPRVQHYRELLDSLPMDAYTHGCILHPELTVDSMIPAYATTRIRSQIGNTESELKKLAEENPDLQEAYIAKQKRLKSKLLDHDNVKYLKKILDELEKVLDQVETELQRRNEETPEEG-QQPWLCGESFTLADVSLAVTLHRLKFLGFARRNWGNGKRPNLETYYERVLKRKTFNKVLGHVNNILISAVLPTAFRVAKKRAPKVLGTTLVVGLLAGVGYFAFMLFRKRLGSMILAFRPRPNYF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VRJ3-1", "uniprot_id": "Q9VRJ3_DROME", "id": "Q9VRJ3-1", "name": "", "aln": "----------------------------------------------------------------MSEQTKEIEALPPTLQDFKAPDLPANKPVLFFHPYNFHAQKVLMVFYEKKIDFFPYVVDLCNGEQYSNWFLNLNPKGDVPVLQDGALVIPSSTHIINYVESKFRGDRS--LKPAHNSKEFDQMLIFEQAMARLPVGTLSLGSFIHDDLKLVPKAPFIGPVRQSCLK-NNEKVLDLLRHSVDEQATKKAALQHKLDIQLRRHE----LASSREEFQKVLDAVRHFLLYVEQELTAQAPRVEWLTGDELSVADISLGLLLHRLYQLGFENQFWTFGKLPQVEAYFLRFRQRESFHRLQ------------PSNFAILREMWTRTPGNYKLG---AGAGFLGMAMFAAFAHK------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:.: .* .. * :. : :*:. .:.* :*** :*: ** :. : *.* .*: . **:.**. *:**** .* :* .:*:**:*:*..* .:*: * * . * : :: :.: : **:.: : *.::* :*.: . * ...* *.*. *. * .. : * *::*. :* *: * . :*::**** *. * ::* . :. . ** *:.:::**:**.: **** *** .: * ** *::*:*: *. :*::*::: *: * : :: .:. *. : .* *::.: :* . ", "identical_positions": 89, "similar_positions": 122, "identity": "20.94%" }, { "cls_id": "homologset.agr.RGD:1309006", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZF19-1", "uniprot_id": "D3ZF19_RAT", "id": "D3ZF19-1", "name": "", "aln": "MINNNQTCAAGQDSVPYVTCMLHVLEEWLGVEQLEDYLNFANHLLWVFTPLIL-LILPYFTIFLLYLTIIFLHIYK-RKNVLKEAYS--HNLWDGARKTVATLWDGHAAVWHGYEVHGMEKIPE-GPALIIFYHGAIPIDFYYFMAKIFIHKGRTCRVVADHFVFKIPGFSLLLDVFCALHGPREKCVEILRSGHLLAISPGGVREALLSDETYNIIWGNRKGFAQVAIDAKVPIIPMFTQNIREGFRSLGGTR-LFKWLYEKFRYPFAPMYGGFPVKLRTFLGDPIPYDPEVTAEELAEKTKNAVQALIDKHQRIPGNIRSALLDRFHKEQKAN-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D850-1", "uniprot_id": "DIESL_MOUSE", "id": "Q9D850-1", "name": "DGAT1/2-independent enzyme synthesizing storage lipids", "aln": "MIDNNQTCAAGQDSVPYVTCMIYVLEEWLGVEQLEDYLNFANHLLWVFTPLIL-LILPYFTIFLLYLTIIFLHIYK-RKNVLKEAYS--HNLWDGARKTVATLWDGHAAVWHGYEVHGMEKIPE-GAALIIFYHGAIPIDFYYFMAKIFIQKGRTCRVVADHFVFKIPGFSLLLDVFCALHGPREKCVEILRSGHLLAISPGGVREALLSDETYNIIWGNRKGFAQVAIDAKVPIIPMFTQNIREGFRSLGGTR-LFKWLYEKFRYPFAPMYGGFPVKLRTFLGDPIPYDPKVTAEELAEKTKNAVQALIDKHQRIPGNIRSALLDRFHKEQKAH-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96MH6-1", "uniprot_id": "DIESL_HUMAN", "id": "Q96MH6-1", "name": "DGAT1/2-independent enzyme synthesizing storage lipids", "aln": "MIDKNQTCGVGQDSVPYMICLIHILEEWFGVEQLEDYLNFANYLLWVFTPLIL-LILPYFTIFLLYLTIIFLHIYK-RKNVLKEAYS--HNLWDGARKTVATLWDGHAAVWHGYEVHGMEKIPEDGPALIIFYHGAIPIDFYYFMAKIFIHKGRTCRVVADHFVFKIPGFSLLLDVFCALHGPREKCVEILRSGHLLAISPGGVREALISDETYNIVWGHRRGFAQVAIDAKVPIIPMFTQNIREGFRSLGGTR-LFRWLYEKFRYPFAPMYGGFPVKLRTYLGDPIPYDPQITAEELAEKTKNAVQALIDKHQRIPGNIMSALLERFH-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VZ05-1", "uniprot_id": "Q9VZ05_DROME", "id": "Q9VZ05-1", "name": "Phospholipid/glycerol acyltransferase domain-containing protein", "aln": "--------------MEFLENLYKTLHSLL--SSYID-LDYSLWLYRFLTPLIVTFLLPLVFVALIYISFLVLFIYKLHRQVIMRAVQGDRNFWRVGRKIVAAIWDAHARIYHGYEVIGLENVPQEGPALIVYYHGAIPIDMYYLNSRMLLQRERLIYTIGDRFLFKLPGWGTISEAFHVSPGTVQSCVSILRDGNLLAISPGGVYEAQFGDHYYELLWRNRVGFAKVAIEAKAPIIPCFTQNLREGFRQVGIFRTFFMRLYNKVRIPVYPIYGGFPVKFRTYLGKPIPYDENLTPQDLQIKVATAIEDLINQHQRLPGSILLALLDRLPTFRRRVRRKEE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: : *.. : .. * *::: * .:****: ::** . : *:*::::.*.*** :::*: .* . :*:* .** **::**.** ::***** *:*::*: *.***::********:**: ::::::: * .:.*:*:**:**:. : :.* . *. :.**.***.*:********* ** :.*. *:::* :* ***:***:**.**** ****:*****.:* * :* **:*.* *. *:*******:**:**.***** ::*.::* *. .*:: **::***:**.* ***:*: ", "identical_positions": 142, "similar_positions": 110, "identity": "41.76%" }, { "cls_id": "homologset.agr.RGD:1309007", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "F1LWN6-1", "uniprot_id": "F1LWN6_RAT", "id": "F1LWN6-1", "name": "Meiotic nuclear division protein 1 homolog", "aln": "-MSKKRGLSGEEKRTRMMEIFFETKDVFQLKDLEKLAPKEKGITAMSVKEVLQSLVD-DGMVDCERIGTSNYYWAFPSKALHARKRKLEALNSQLSEGSQKHADLQKSIEKARVGR--------QETEERAMLAKELSSFQDQRKKLKAEVEKYR--ECDPQVVEEIRQANKVAKEAANRWTDNIFA---IKSWAKRKYGFEE---TKIDKNFGIP-----EDFDYVD----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K396-1", "uniprot_id": "MND1_MOUSE", "id": "Q8K396-1", "name": "Meiotic nuclear division protein 1 homolog", "aln": "-MSKKRGLSGEEKRTRMMEIFFETKDVFQLKDLEKLAPKEKGITAMSVKEVLQSLVD-DGMVDCERIGTSNYYWAFPSKALHARKRKLEALNSQLSEGSQKHADLQKSIEKARVGR--------QETEERAMLAKELSSFRDQRQQLKAEVEKYR--ECDPQVVEEIREANKVAKEAANRWTDNIFA---IKSWAKRKFGFEE---SKIDKNFGIP-----EDFDYID----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BWT6-1", "uniprot_id": "MND1_HUMAN", "id": "Q9BWT6-1", "name": "Meiotic nuclear division protein 1 homolog", "aln": "-MSKKKGLSAEEKRTRMMEIFSETKDVFQLKDLEKIAPKEKGITAMSVKEVLQSLVD-DGMVDCERIGTSNYYWAFPSKALHARKHKLEVLESQLSEGSQKHASLQKSIEKAKIGR--------CETEERTRLAKELSSLRDQREQLKAEVEKYK--DCDPQVVEEIRQANKVAKEAANRWTDNIFA---IKSWAKRKFGFEE---NKIDRTFGIP-----EDFDYID----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DC61-1", "uniprot_id": "MND1_DANRE", "id": "Q6DC61-1", "name": "Meiotic nuclear division protein 1 homolog", "aln": "-MSKKKGLSLEEKRSRMMEIFFETKDVFQLKDIEKIAPKSKGITPMSVKEVLQSLVD-DNMVDTERVGTSNYYWAFPSKALHARKRRLEELEKQLEDGSQRKKALQQAVDKAKVGR--------EVNEEREDLLKELTALKGQRDQMKVEIEKYQ--ECDPAVVEEIRNANIAAKEAVARWTGGTFGNYLISYLLTCSLTRQEPWAHHLSPSSGFSPGTACQTCYYYQQAIS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P53102-1", "uniprot_id": "MND1_YEAST", "id": "P53102-1", "name": "Meiotic nuclear division protein 1", "aln": "MGPKRQTVSLQEKKNRILNFFQETYTFYNIKELEKSIPKKCGISPMIVKDLVQQMIDEDGVISVEKCGNINIYWCFKNQTLQKLYDSSELIKKKIQEVKCDIATYKQELDKTLATGRRKKFTVGQKSYNREALLEKRKKIQDEIKKKSNSLQKIESIRWDAAKIQENKQQIRLKKVHLEKTTDNIEIL--IDYLYKKFFLKPE----QIRKEFGIP-----EEFKEFTEV--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .*:: :* :**:.*::::* ** .:::*::** **. **:.* **:::*.::* *.::. *: *. * **.* .::*: * ::.::.: . :: ::*: . :* * :: . ::.: .: . .::* . *. ::* :: * : *.. *. . * :: *:. : ", "identical_positions": 40, "similar_positions": 81, "identity": "17.24%" }, { "cls_id": "homologset.agr.RGD:1309008", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q4V8I4-1", "uniprot_id": "DEFI8_RAT", "id": "Q4V8I4-1", "name": "Differentially expressed in FDCP 8 homolog", "aln": "-------------------------------------------------------------MEYDEKLVRFRQAHLNPFNKHLGPRHHEQEPNEKAQEVTSEDTLPELPAGEPEFCYSERMMDLGLSEDHFSRPVGLFLASDVQQLRQAIEECKQVILELPEQSEKQKDAVVRLIHLRLKLQELKDPNEEE---------PNIRVLLEHRFYKEK----------SKSVKQTCDKCNTIIWGLIQTWYTCTGCYYRCHSKCLNLISRPCVSSKVSHQAEYELNICPETGLDSQDYRCAECRAPISLRGVPSEARQCDYTGQYYCSHCHWNDLAVIPARVVHNWDFEPRKVSRCSMRYLALMVSRPVLRLREINPLLFNYVEELVEIRKLRQDILLMKPYFITCKEAMEARLLLQLQ-DRQHFVENDEMYSIQDLLEVHMGRLSCSLTEIHTIFAKHIKLDCERCQAKGFVCELCKEGDVLFPFDSHTSVCNDCSAVFHRDCYYDNSTTCPKCARLTLRKQSLFQEPGLDVDA----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99J78-1", "uniprot_id": "DEFI8_MOUSE", "id": "Q99J78-1", "name": "Differentially expressed in FDCP 8", "aln": "-------------------------------------------------------------MEYDEKLVRFRQAHLNPFNKQLGPRHHEQEPSEK---VTSEDTLPELPAGEPEFHYSERMMDLGLSEDHFSRPVGLFLASDVQQLRQAIEECKQVILELPEQSEKQKDAVVRLIHLRLKLQELKDPNEEE---------PNIRVLLEHRFYKEK----------SKSVKQTCDKCNTIIWGLIQTWYTCTGCCYRCHSKCLNLISKPCVSSKVSHQAEYELNICPETGLDSQDYRCAECRAPISLRGVPSEARQCDYTGQYYCSHCHWNDLAVIPARVVHNWDFEPRKVSRCSMRYLALMVSRPVLRLREINPLLFNYVEELVEIRKLRQDILLMKPYFITCKEAMEARLLLQLQ-DRQHFVENDEMYSIQDLLEVHMGRLSCSLTEIHTLFAKHIKLDCERCQAKGFVCELCKEGDVLFPFDSHTSVCNDCSAVFHRDCYYDNSTTCPKCARLTLRKQSLFQEPGLDMDA----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZN54-1", "uniprot_id": "DEFI8_HUMAN", "id": "Q6ZN54-1", "name": "Differentially expressed in FDCP 8 homolog", "aln": "MAILSLRAPGPWQAMQVWADRTLLTPHTGVTSQVLGVAAAVMTPLPGGHAAGRTREARWDAMEYDEKLARFRQAHLNPFNKQSGPRQHEQGPGEEVPDVTPEEALPELPPGEPEFRCPERVMDLGLSEDHFSRPVGLFLASDVQQLRQAIEECKQVILELPEQSEKQKDAVVRLIHLRLKLQELKDPNEDE---------PNIRVLLEHRFYKEK----------SKSVKQTCDKCNTIIWGLIQTWYTCTGCYYRCHSKCLNLISKPCVSSKVSHQAEYELNICPETGLDSQDYRCAECRAPISLRGVPSEARQCDYTGQYYCSHCHWNDLAVIPARVVHNWDFEPRKVSRCSMRYLALMVSRPVLRLREINPLLFSYVEELVEIRKLRQDILLMKPYFITCREAMEARLLLQLQ-DRQHFVENDEMYSVQDLLDVHAGRLGCSLTEIHTLFAKHIKLDCERCQAKGFVCELCREGDVLFPFDSHTSVCADCSAVFHRDCYYDNSTTCPKCARLSLRKQSLFQEPGPDVEA----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VTT9-1", "uniprot_id": "DEFI8_DROME", "id": "Q9VTT9-1", "name": "Differentially expressed in FDCP 8 homolog", "aln": "-----------------------------------------------------MSSWKDSLTSIPGTVAQLINESASNLLHASSTLGSTVGLGGSGSTGSGSEAGGSEESGPQGAEYRALPIPASLVREQWR--LIFTSDANIQDLQAAIAHCRDLVLLSEELSEERRWLVRHLVDLRYSLQELEEAQEQHSLSSDMVVMNAIRAVVGHHFVPHHPHHGKRNRLQAAAKRNYCDHCTTIIWSVVQNSYVCSDCGFLVHQKCIDGVKRVCAHVLVSERQHPISEICPEIGLASQGYKCAECGTMLNIKNTWIEPRLCDYSGLYYCPRCNWNDSNFIPARIIHNWDFSPRRVSRTALQEIRLFLNKPLIRLEEDNPKLFVFVEKLCAVKKLRQNLVHMRHYLAACKIASELKLVDQQLGVRRHLAQSNEFYSLSDLSQVESGALSEFLQGVFKAFNDHIRS-CPMCLAQAYICEICSNNEVIFPFDDGCIKCDQCNSIFHRVCLTRKNMICPKCIRIQERRLQLDRMKSTEDDDDDDDGVATDDDVTAAE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .:.:: : . : : .. . . : .:: . .* : .* .::: : : :::*:*: ** .*::::* * **::: * :*:.** .****::.:*:. **.:: *:* .: : : :: **:*.****.::*. *.*:.* : *.**:: :.: *. **.: . :**** ** **.*:**** : :.::.. *.* ***:* ***.:*:*** .****::*****.**:*** ::: : *::.:*::**.* ** ** :**:* ::****::: *: *: :*: * * :*: * *:*:.:.:*:**:.** :*. * *. * :.. * .**: * * *:.::**:* :.:*:****. * :*.::*** * :. **** *: *: .* : . : : ", "identical_positions": 142, "similar_positions": 165, "identity": "25.91%" }, { "cls_id": "homologset.agr.RGD:1309009", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K3L9-1", "uniprot_id": "A0A0G2K3L9_RAT", "id": "A0A0G2K3L9-1", "name": "", "aln": "---MMCEVMPTISEAEGPPGGGGSHGSGSPSQPDADSHFEQLMVSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQEFAALTKELNVCREQLLEREEEIAELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPAGVSSEVEVLKALKSLFEHHKALDEKVRERLRVALERCSLLEEELGATHKELMILKE-----------QNSQKKALTEGMLDGNHEQENAPSTNGKRSSDGSLSHED--LAKVLELQEVIDRQAREQSQMKERLASLSSHAAELEEDLDTARKDLIKSEEMNTKLQREVREAMAQKEDMEERITTLEKRYLAAQREATSVHDLNDKLENEIANKDSMHRQTEDKNRQLQERLELAEQKLQQTLRKAETLPEVEAELAQRVAALSKSGPLSSGSSAAKEAKLLELTSKLRKAEERHGNIEERLRQMEAQLEEKNQELQRARQREKMNEEHNKRLSDTVDKLLSESNERLQLHLKERMAALEDKNSLLREVENAKKQLEETQHDKDQLVLNIEALKAELEQMR-----------LRGSSLHHGRPHLGSVPDFRFSVADGHVDAYSTSAVLRRPQKGRLAALRDEPSKVQTLNEQDWERAQQASVLANVAQAFESDVDVSDGEDDRDTLLSSVDLLSPSGQADAQTLAMMLQEQLDAINKEIRLIQEEKENTEQRAEEIESRVGS-GSLDNLGRFRSMSSIPPYPASSLAGSSPPG----SGRSTPRRVPHSPAREVDRLGVMTLPSDLRKHRRQLPASREEVRDDKTTIKCETSPPSSPR-PLRLDR------LHKGALHTVS--HEDIRDLRNSTGSQDGP-----------VSNPSSSNSSQDSLHKAPKKKGIKSSIGRLFGKKEKGR-------PGPLGKESPG--QAGVSETENSSQDALGLS-------------KLG--GQAEKNRKLQKKHELLEEARRQGLPFAQWDGPTVVVWLELWVGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNPLHRLKLRLAIQEIMSLTSPSAPPTSRTTTGNVWLTHEEMETLTATPQTEDEEGSWAQTLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRGQLKMVDSFHRNSFQCGIMCLRRLNYDRKELERKREESQNETRDVLVWSNDRVIRWILSIGLKEFANNLIESGVHGALLALDETFDFSALALLLQIPTQNTQARAVLEREFNNLLVTGTDRRFDEDDDKSFRRAPSWRKKFRPKDIRGLASGSAETLPANFRVTSSMSSPSMQPKKVQMDGSVSGAQRLDSATVRTYSC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13136-1", "uniprot_id": "LIPA1_HUMAN", "id": "Q13136-1", "name": "Liprin-alpha-1", "aln": "---MMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLMVSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQEFAALTKELNVCREQLLEREEEIAELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPAGVSSEVEVLKALKSLFEHHKALDEKVRERLRVALERCSLLEEELGATHKELMILKE-----------QNNQKKTLTDGVLDINHEQENTPSTSGKRSSDGSLSHEED-LAKVIELQEIISKQSREQSQMKERLASLSSHVTELEEDLDTARKDLIKSEEMNTKLQRDVREAMAQKEDMEERITTLEKRYLAAQREATSVHDLNDKLENEIANKDSMHRQTEDKNRQLQERLELAEQKLQQTLRKAETLPEVEAELAQRVAALS-------------------------KAEERHGNIEERLRQMEAQLEEKNQELQRARQREKMNEEHNKRLSDTVDKLLSESNERLQLHLKERMAALEDKNSLLREVESAKKQLEETQHDKDQLVLNIEALRAELDHMR-----------LRGASLHHGRPHLGSVPDFRFPMADGHTDSYSTSAVLRRPQKGRLAALRDEPSKVQTLNEQDWERAQQASVLANVAQAFESDADVSDGEDDRDTLLSSVDLLSPSGQADAHTLAMMLQEQLDAINKEIRLIQEEKENTEQRAEEIESRVGS-GSLDNLGRFRSMSSIPPYPASSLASSSPPG----SGRSTPRRIPHSPAREVDRLGVMTL----------LPPSREEVRDDKTTIKCETSPPSSPR-ALRLDR------LHKGALHTVS--HEDIRDIRNSTGSQDGP-----------VSNPSSSNSSQDSLHKAPKKKGIKSSIGRLFGKKEKGR-------PGQTGKEALG--QAGVSETDNSSQDALGLS-------------KLG--GQAEKNRKLQKKHELLEEARRQGLPFAQWDGPTVVVWLELWVGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNPLHRLKLRLAIQEIMSLTSPSAPPTSRTT------------------------------LAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRGQLKMVDSFHRNSFQCGIMCLRRLNYDRKELERKREESQSEIKDVLVWSNDRVIRWILSIGLKEYANNLIESGVHGALLALDETFDFSALALLLQIPTQNTQARAVLEREFNNLLVMGTDRRFDEDDDKSFRRAPSWRKKFRPKDIRGLAAGSAETLPANFRVTSSMSSPSMQPKKMQMDGNVSGTQRLDSATVRTYSC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M9PCD4-1", "uniprot_id": "M9PCD4_DROME", "id": "M9PCD4-1", "name": "", "aln": "MWNMMCDVMPTISED--------SISQRSSQFSGEDANFEQLMVSMLDERDKLMDSLREAQERLNETENKLRDVEKERDSLQRQINANLPQEFATLTKELTQARETLLERDEEIGELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAAAQSGVSSEVEVLKALKSLFEHHKALDEKVRERLRLSIEKNNMMEEELSSAKEELAQYKAGVVPAGVGSGSGAGSAATTAGGGGAENGLKEKMAGVGGSGGVNGEANELNDYAAKTHELQTIIEKQTSELSQWQRRVSDLNNKISELEENMSRVQKEHCKAQDQCAKLQRDLRENVAQKEDQEERITTLEKRYLNAQRESTSLHDLNEKLEQELRHKEAQLKLHEEKIGAIEEKLELSEQKLAQ---HAKLQPDMEEQLKARMEALT-------------------------KAQERHGSAEDRIRGLETNLDEKTNEVVRLNQRLKMNEEHNLRLSSTVDKLLSESNERLQVHLKERMHALDEKNALTQELEKARKVAEELHHEKSEIMKELSKTRLEIENFKRQLLQQEIAYNIQQTEALTRSLSPSSVVDPSGAFSRSNSHASFETHSLRRQSKQRLS---EENALVRSMAEQEWEKLQQAAHAQQQAYELASAADCDDSD---VLYAAATDMMSPSGHTDAQTLAMMLQEQLDAINNEIRLIQEEKQSTEARAEELESRVGSLEHVNLLARGRSMDRQSPPMSGRSTPNSPQRDFMQKYHTLNLPVLSSDASREELHGGMSTTGDSSSGGAASPLTARSMRLERVAQALAHSQEELRRRSIGLNPNASVAPNHTGGHMPLSSHSYGLSPLSSRYGSQESLRHYNTMGSMSMLQTPTSGVSREAAAAAVQKKKGIKSSLGRFFSKKEKVKGVKDTLPDGSPSMMSIGNLSIGLSEVD-SNYDAMSMTGGMMPRIASSQGSKISSVDYGRQKKEHDYRNDLLGEAMKAGTPFALWNGPTIVAWLELWVGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNPLHRLKLRLAIQEMVSLTSPSAPQTSRTT------------------------------LAFGDMNHEWIGNYWLPGLGLPQYRTTFMECLVDARMLDHLTKKDLRGQLKMVDSFHRTSLQYGISMLKRLNYDRTELEHRRKMSENGLCDVLVWSNERVIRWVGSIGLKEYANNLLESGVHGGLMALDEGFDANAMGLALQIPTQNAQARQILDTEFNNLLQIATDRRPENE-----QRSASX---------------------------CSYSPPTSSVDE-----------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***:******* . .. *.. .. *::*********:***:*:*:***:** * *:.**::* :********:*: ******:*****. .** ****:***.************************************ : :*******************************:::*: .::****.::::** * .. : : * * :*: ....*. . :*. .. : **. *** :*.:*: * ** :.*::.*..: :****::. .:*: *::: :****::** :***** ************ ****:**:****:***:*: :*:: : *:* ::*:***:**** * :*: *::* :* *: **: **:****. *:*:* :*::*:**.:*: * .** ******* ***.**************:****** **::**:* :*:*.*:* ** :*:*.::: ::. : *::::: :: :. .** * ..: .: .: : *** .* **: :* : *::: **:**: ***: : * : * .* .*.: ::.*::****::**:**************:*********:.** ****:****** :: *.* ***. .* :. : .** . :: : * * . : * *: * : ..:* ::.: * . * .: *: *.*. .:* .: : . ***:. :..*:*. * : : . ********:**:*.**** : * . : * . *:**.: *. **:.:: *:. . ..:::: : :::** ** : * *** *:***:*.*******************************************************::******** ***** **:********** ***.*******: *******************************.*:* ** *:******.***::*: *:. *******:*****: ******:****:******.*:**** ** .*:.* *******:*** :*: ****** .**** ::: :*:.* .* *.*: . .: ", "identical_positions": 607, "similar_positions": 300, "identity": "45.23%" }, { "cls_id": "homologset.agr.RGD:1309010", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "B5DEH2-1", "uniprot_id": "ERLN2_RAT", "id": "B5DEH2-1", "name": "Erlin-2", "aln": "MAQLGAVVAVASSFFCASLFSAVHKIEEGHIGVYYRGGALLTSTSGPGFHLMLPFITSYKSVQTTLQTDEVKNVPCGTSGGVMIYFDRIEVVNFLVPHAVYDIVKNYTADYDKALIFNKIHHELNQFCSVHTLQEVYIELFDQIDENLKLALQQDLTSMAPGLVIQAVRVTKPNIPEAIRRNYELMESEKTKLLIAAQKQKVVEKEAETERKKALIEAEKVAQVAEITYGQKVMEKETEKKISEIEDAAFLAREKAKADAECYTALKIAEANKLKLTPEYLQLMKYKAIASNSKIYFGKDIPNMFMDSAGGLGKQSEGLS-DKLGFGLEDEPLETATKDN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BFZ9-1", "uniprot_id": "ERLN2_MOUSE", "id": "Q8BFZ9-1", "name": "Erlin-2", "aln": "MAQLGAVVAVASSFFCASLFSAVHKIEEGHIGVYYRGGALLTSTSGPGFHLMLPFITSYKSVQTTLQTDEVKNVPCGTSGGVMIYFDRIEVVNFLVPNAVYDIVKNYTADYDKALIFNKIHHELNQFCSVHTLQEVYIELFDQIDENLKLALQQDLTSMAPGLVIQAVRVTKPNIPEAIRRNYELMESEKTKLLIAAQKQKVVEKEAETERKKALIEAEKVAQVAEITYGQKVMEKETEKKISEIEDAAFLAREKAKADAECYTALKIAEANKLKLTPEYLQLMKYKAIASNSKIYFGKDIPNMFMDSAGGLGKQFEGLSDDKLGFGLEDEPLEAPTKEN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O94905-1", "uniprot_id": "ERLN2_HUMAN", "id": "O94905-1", "name": "Erlin-2", "aln": "MAQLGAVVAVASSFFCASLFSAVHKIEEGHIGVYYRGGALLTSTSGPGFHLMLPFITSYKSVQTTLQTDEVKNVPCGTSGGVMIYFDRIEVVNFLVPNAVYDIVKNYTADYDKALIFNKIHHELNQFCSVHTLQEVYIELFDQIDENLKLALQQDLTSMAPGLVIQAVRVTKPNIPEAIRRNYELMESEKTKLLIAAQKQKVVEKEAETERKKALIEAEKVAQVAEITYGQKVMEKETEKKISEIEDAAFLAREKAKADAECYTAMKIAEANKLKLTPEYLQLMKYKAIASNSKIYFGKDIPNMFMDSAGSVSKQFEGLA-DKLSFGLEDEPLETATKEN", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*************************************************************************************************:***********************************************************************************************************************************************************************:********************************************.:.** ***: ***.*********:.**:*", "identical_positions": 328, "similar_positions": 10, "identity": "96.47%" }, { "cls_id": "homologset.agr.RGD:1309012", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5BK46-1", "uniprot_id": "RNH1_RAT", "id": "Q5BK46-1", "name": "Ribonuclease H1", "aln": "MRWLLPLFRTVTLAVVRVRRGVCGLG-MFYAVRRGRRTGVFLSWSECKAQVDRFPAARFKKFATEDEAWAFVRSSSSPDGSKGQESAHVQKLQVK------------------------------------------------------------TSKRPREPL-GEEEEPPEPGAKHTRQDTEPAALVSKDAFS---------YMGESVVVYTDGCCSSNGRKRARAGIGVYWGPGHPLNVGIRLP-GRQTNQRAEIHAACKAITQAKAQNIS-----KLVLYTDSMFTINGITNWVQGWKKNGWRTSTGKDVIN----------KEDFMELDELTQGMDIQWMHIPGHSGFVGNEEADRLAREGAKQSEG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70338-1", "uniprot_id": "RNH1_MOUSE", "id": "O70338-1", "name": "Ribonuclease H1", "aln": "MRWLLPLSRTVTLAVVRLRRGICGLG-MFYAVRRGRRTGVFLSWSECKAQVDRFPAARFKKFATEDEAWAFVRSSSSPDGSKGQESAHEQKSQAK------------------------------------------------------------TSKRPREPL-GEGEELPEPGPKHTRQDTEPAAVVSKDTFS---------YMGESVIVYTDGCCSSNGRKRARAGIGVYWGPGHPLNVGIRLP-GRQTNQRAEIHAACKAIMQAKAQNIS-----KLVLYTDSMFTINGITNWVQGWKKNGWRTSTGKDVIN----------KEDFMELDELTQGMDIQWMHIPGHSGFVGNEEADRLAREGAKQSED", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60930-1", "uniprot_id": "RNH1_HUMAN", "id": "O60930-1", "name": "Ribonuclease H1", "aln": "MSWLLFLAHRVALAALPCRRGSRGFG-MFYAVRRGRKTGVFLTWNECRAQVDRFPAARFKKFATEDEAWAFVRKSASPEVSEGHENQHGQESEAK------------------------------------------------------------ASKRLREPLDGDGHESAEPYAKHMKPSVEPAPPVSRDTFS---------YMGDFVVVYTDGCCSSNGRRRPRAGIGVYWGPGHPLNVGIRLP-GRQTNQRAEIHAACKAIEQAKTQNIN-----KLVLYTDSMFTINGITNWVQGWKKNGWKTSAGKEVIN----------KEDFVALERLTQGMDIQWMHVPGHSGFIGNEEADRLAREGAKQSED", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N0V4-1", "uniprot_id": "A0A8M1N0V4_DANRE", "id": "A0A8M1N0V4-1", "name": "Ribonuclease H1", "aln": "MLRLPGFLNVVRRTLCNAAEEMGKKGNFFYAVRKGFKPGVYQTWEECKHQVDKFPSASFKKFASEQDALDFVRSHSDASSSAGANGCELEVLPPRNVPCSSM-------------------------------------------------AVSFGSKRTHDETEDEGPSCPKR-VKLIEVPQPKTGTTSSDGFT---------YMGDAVVVYTDGCCSGNGKHGARAGIGVYWGRDHPRNVAERLP-GRQTNQRAELQAACKALEQAKEMNFK-----KVVLYTDSKFTINGVTSWVKTWKSNGWRLKSGGVIIN----------KDDFQQLDKLNAELDVVWMHIPGHAGYTGNEEADRLSREGAAKPTC", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q04740-1", "uniprot_id": "RNH1_YEAST", "id": "Q04740-1", "name": "Ribonuclease H", "aln": "---------------------MARQG-NFYAVRKGRETGIYNTWNECKNQVDGYGGAIYKKFNSYEQAKSFLGQPNTTSNYGSSTHAGGQVSKPHTTQKRVHRRNRPLHYSSLTSSSACSSLSSANTNTFYSVKSNVPNIESKIFNNWKDCQAYVKHKRGITFKKFEDQLAAENFISGMSAHDYKLMNISKESFESKYKLSSNTMYNKSMNVYCDGSSFGNGTSSSRAGYGAYFEGAPEENISEPLLSGAQTNNRAEIEAVSEALKKIWEKLTNEKEKVNYQIKTDSEYVTKLLNDRYMTYDNKKLEGLPNSDLIVPLVQRFVKVKKYYELNKECFKNNGKFQIEWVKGHDGDPGNEMADFLAKKGASRR--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *****:* ..*:: :*.**: *** : .* :*** : ::* *: . .. . : : ** : .: . * : * .. : ** **.. .** .*** *.*: *:. * * ***:***:.*..:*: : . : : *** :. : :.. :..: . .. :* * : :. .. : ** * *** ** *:::** : ", "identical_positions": 62, "similar_positions": 72, "identity": "16.67%" }, { "cls_id": "homologset.agr.RGD:1309013", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "F1MAQ7-1", "uniprot_id": "F1MAQ7_RAT", "id": "F1MAQ7-1", "name": "Protein SON", "aln": "MAADIEQVFRSFVVSKFREIQQELSSGRSEGQLNGETNAPIEGNQAGDTAASARSLPNEEIVQKIEEVLSGVLDTELRYKPDLKEASRKSRCVSVQTDPTDEVPTKKSKKHKKHKNKKKKKKKEKEKKYKRQPEESESKLKSHHDGNVDLESDSFLKFDSEPSALALEHPVRAFGLSEASET-PLVLEPPVVSMEVQEPHALETLKPATKPAALSAVSTSVISEQPEQPVPVMLEPSMTKILDSFAAAPVPMSTAVLRSPEPVVTMSVEYQ-KSVLKSLETVPPEISKTTLVELPIAKVLEPSETLTIVSETPTEVHPEPSPS-TMDFPESSTTDVQRLPEQPVEAPPEIADSSMTRPQESLELPKTTAVELQESSVASALELPGPPATSMLELQGPPVTPVPELPGPSATTPVPELSGPLSTLVPELPGPPGTVVPELPGPSVTPVPQLSQELPGPSAPSMGLEPPQEVPEPPVMAQEVSGVPTVSAAIELTGQPAVTVAMELTEQPVTTTEFEQPVAMTTVEHPGHPEVTTATGLLGQPEAAMVLELPGQPVATTALELSGQPSVTGVPELSGLPSATRALELSGQSVATGALELPGQLMATGALEFSGQSGAAGALELLGQPLATGVLELPGQPGAPELPGQPVATVALEISVQSVVTTSELSTMTVSQSLEVPSTTALESYNTVAQELPTTLVGETSVTVGVDPLMAQESHMLASNTMETHMLASNTMDSQMLASNTMDSQMLASNTMDSQMLASSTMDSQILASSTMDSQMLATSSMDSQMLASSSMDSQMLATSSMDSQMLATSSMDSQMLATSSMDSQMLATSSMDSQMLATSSMDSQMLATSSMDSQMLATSSMDSQMLASGAMDSQMLASGTMDAQMLASGTMDAQMLASSTQDSAMMGSKSPDPYRLAQDPYRLAQDPYRLGHDPYRLGHDAYRLGQDPYRLGHDPYRLTPDPYRMSPRPYRIAPRSYRIAPRPYRLAPRPLMLASRRSMMMSYAAERSMMSSYERSMMSYERSMMSPMAERSMMSAYERSMMSAYERSMMSPMAERSMMSAYERSMMSAYERSMMSPMADRSMMSMGADRSMMSSYSAADRSMMSSYSAADRSMMSSYT-DRSMMSMAADSYTDSYTDSYTEAYMVPPLPPEEPPTMPPLPPEEPPMTPPLPPEEPPEGAALSTEQSALTADNTWSTEVTLP-TEESVSQPEPPVSQSEISEPLVVPANYSASESETSMLASEAVMTVPEPAREPESSVTSTPVESAVVA-EHEMVPERPMTYMVSET-TMAAEPSVLTSEASVMAETSETYDSMRPSGHAISEVSMSLLEPAVTISQPAESSLELPSMAVPAPSTIATTES-LVAVPELAAVADSEPPIMAVPEPPTVAVPEP-------PVTTAPEPPPMITPELCSLSISESPVAVSELPALADPEHAVTAVSGVSSLEPSVPVLEPSVSVLQPVMIVSEPCVSIQEPTVAVSEPAVIVSEHTQITSPEMAVESSPVMVESSVVSSQIMKGMNLLSGDENLGSEVGTQETLLHPGEEPHDGGHLKSDLYEHEYDRNTDLTVNSHLIAKEAEHSTACAAAIVPVGETSEEKILPISETKEMIELDTCPAVSEADVGRSLSS--QLALELDTVGTSKGFEFVAASAPISESKYDVEVSVTTQDTEHDMVISTSPSGGSEADIEGPLPAKDIHLDLPSTN-LVCKDVEDSLPIKESDETVTVALSPKESSE-DTEGPLPNKEIVPDSGYSVSIDEINEADLVRPLLPKDMERLTSLRAGIEGPLLPSEVERDKSVASPVVISIPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGRSPKRLTDLDKAQLLEIAKAN-AAAMCAKAGVPLPPNLKPAPPPTIEEKVAKKSGGATIEELTEKCKQIAQSKEDDDVIVNKPHVSDEEEEEPPFYHHPFKLSEPKPIFFNLNIAAAKPTPPKSQVTLTKEFPVSSGSQHRKKEADSVYGEWVPVEKNGEESKDDDNVFSSSLPSEPVDISTAMSERALAQKRLSENAFDLEAMSMLNRAQERIDAWAQLNSIPGQFTGSTGVQVLTQEQLANTGAQAWIKKDQFLRAAPVTGGMGAVLMRKMGWREGEGLGKNKEGNKEPILVDFKTDRKGLVAVGER---------AQKRSGNFSAAMKD--------------------LSGKHPVSALMEICNKRRWQPPEFLLVHDSGPDHRKHFLFRVLRNGSPYQPN----------------CMFFLNRY---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QX47-1", "uniprot_id": "SON_MOUSE", "id": "Q9QX47-1", "name": "Protein SON", "aln": "MAADIEQVFRSFVVSKFREIQQELSSGRSEGQLNGETNPPIEGNQAGDTAASARSLPNEEIVQKIEEVLSGVLDTELRYKPDLKEASRKSRCVSVQTDPTDEVPTKKSKKHKKHKNKKKKKKKEKEKKYKRQPEESESKLKSHHDG--NLESDSFLKFDSEPSAAALEHPVRAFGLSEASET-ALVLEPPVVSMEVQESHVLETLKPATKAAELSVVSTSVISEQSEQPMPGMLEPSMTKILDSFTAAPVPMSTAALKSPEPVVTMSVEYQ-KSVLKSLETMPPETSKTTLVELPIAKVVEPSETLTIVSETPTEVHPEPSPS-TMDFPESSTTDVQRLPEQPVEAPSEIADSSMTRPQESLELPKTTAVELQESTVASALELPGPPATSILELQGPPVTPVPELPGPSAT-PVPELSGPLSTPVPELPGPPATVVPELPGPSVTPVPQLSQELPGPPAPSMGLEPPQEVPEPPVMAQELSGVPAVSAAIELTGQPAVTVAMELTEQPVTTTEFEQPVAMTTVEHPGHPEVTTATGLLGQPEAAMVLELPGQPVATTALELSGQPSVTGVPELSGLPSATRALELSGQSVATGALELPGQLMATGALEFSGQSGAAGALELLGQPLATGVLELPGQPGAPELPGQPVATVALEISVQSVVTTSELSTMTVSQSLEVPSTTALESYNTVAQELPTTLVGETSVTVGVDPLMAQESHMLASNTMETHMLASNTMDSQMLASNTMDSQMLASNTMDSQMLASSTMDSQMLASSTMDSQMLATSTMDSQMLATSSMDSQMLATSSMDSQMLATSSMDSQMLATSSMDSQMLATSSMDSQMLATSSMDSQMLATSSMDSQMLATSSMDSQMLASGAMDSQMLASGTMDAQMLASGTMDAQMLASSTQDSAMMGSKSPDPYRLAQDPYRLAQDPYRLGHDPYRLGHDAYRLGQDPYRLGHDPYRLTPDPYRVSPRPYRIAPRSYRIAPRPYRLAPRPLMLASRRSMMMSYAAERSMMSSYERSMMSYERSMMSPMAERSMMSAYERSMMSAYERSMMSPMAERSMMSAYERSMMSAYERSMMSPMADRSMMSMGADRSMMSSYSAADRSMMSSYSAADRSMMSSYT-DRSMMSMAADSYTDSYTDSYTEAYMVPPLPPEEPPTMPPLPPEEPPMTPPLPPEEPPEGPALSTEQSALTADNTWSTEVTLS-TGESLSQPEPPVSQSEISEPMAVPANYSMSESETSMLASEAVMTVPEPAREPESSVTSAPVESAVVA-EHEMVPERPMTYMVSET-TMSVEPAVLTSEASVISETSETYDSMRPSGHAISEVTMSLLEPAVTISQPAENSLELPSMTVPAPSTMTTTESPVVAVTEIPPVAVPEPPIMAVPELPTMAVVKTPAVAVPEPLVAAPEPPTMATPELCSLSVSEPPVAVSELPALADPEHAITAVSGVSSLEPSVPILEPAVSVLQPVMIVSEPSVPVQEPTVAVSEPAVIVSEHTQITSPEMAVESSPVIVDSSVMSSQIMKGMNLLGGDENLGPEVGMQETLLHPGEEPRDGGHLKSDLYENEYDRNADLTVNSHLIVKDAEHNTVCATTVGPVGEASEEKILPISETKEITELATCAAVSEADIGRSLSS--QLALELDTVGTSKGFEFVTASALISESKYDVEVSVTTQDTEHDMVISTSPSGGSEADIEGPLPAKDIHLDLPSTN-FVCKDVEDSLPIKESAQAVAVALSPKESSE-DTEVPLPNKEIVPESGYSASIDEINEADLVRPLLPKDMERLTSLRAGIEGPLLASEVERDKSAASPVVISIPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKAARARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRS-------RTPSRRSRTPSRRRRSRSAVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGRSPKRLTDLDKAQLLEIAKAN-AAAMCAKAGVPLPPNLKPAPPPTIEEKVAKKSGGATIEELTEKCKQIAQSKEDDDVIVNKPHVSDEEEEEPPFYHHPFKLSEPKPIFFNLNIAAAKPTPPKSQVTLTKEFPVSSGSQHRKKEADSVYGEWVPVEKNGEESKDDDNVFSSSLPSEPVDISTAMSERALAQKRLSENAFDLEAMSMLNRAQERIDAWAQLNSIPGQFTGSTGVQVLTQEQLANTGAQAWIKKDQFLRAAPVTGGMGAVLMRKMGWREGEGLGKNKEGNKEPILVDFKTDRKGLVAVGER---------AQKRSGNFSAAMKD--------------------LSGKHPVSALMEICNKRRWQPPEFLLVHDSGPDHRKHFLFRVLRNGSPYQPN----------------CMFFLNRY---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P18583-1", "uniprot_id": "SON_HUMAN", "id": "P18583-1", "name": "Protein SON", "aln": "MATNIEQIFRSFVVSKFREIQQELSSGRNEGQLNGETNTPIEGNQAGDAAASARSLPNEEIVQKIEEVLSGVLDTELRYKPDLKEGSRKSRCVSVQTDPTDEIPTKKSKKHKKHKNKKKKKKKEKEKKYKRQPEESESKTKSHDDGNIDLESDSFLKFDSEPSAVALELPTRAFGPSETNESPAVVLEPPVVSMEVSEPHILETLKPATKTAELSVVSTSVISEQSEQSVAVMPEPSMTKILDSFAAAPVPTTTLVLKSSEPVVTMSVEYQMKSVLKSVESTSPEPSKIMLVEPPVAKVLEPSETLVVSSETPTEVYPEPSTSTTMDFPESSAIEALRLPEQPVDVPSEIADSSMTRPQELPELPKTTALELQESSVASAMELPGPPATSMPELQGPPVTPVLELPGPSAT-PVPELPGPLSTPVPELPGPPATAVPELPGPSVTPVPQLSQELPGLPAPSMGLEPPQEVPEPPVMAQELPGLPLVTAAVELPEQPAVTVAMELTEQPVTTTELEQPVGMTTVEHPGHPEVTTATGLLGQPEATMVLELPGQPVATTALELPGQPSVTGVPELPGLPSATRALELSGQPVATGALELPGPLMAAGALEFSGQSGAAGALELLGQPLATGVLELPGQPGAPELPGQPVATVALEISVQSVVTTSELSTMTVSQSLEVPSTTALESYNTVAQELPTTLVGETSVTVGVDPLMAPESHILASNTMETHILASNTMDSQMLASNTMDSQMLASNTMDSQMLASSTMDSQMLATSSMDSQMLATSSMDSQMLATSTMDSQMLATSSMDSQMLATSSMDSQMLATSSMDSQMLATSSMDSQMLATSTMDSQMLATSTMDSQMLATSSMDSQMLASGTMDSQMLASGTMDAQMLASGTMDAQMLASSTQDSAMLGSKSPDPYRLAQDPYRLAQDPYRLGHDPYRLGHDAYRLGQDPYRLGHDPYRLTPDPYRMSPRPYRIAPRSYRIAPRPYRLAPRPLMLASRRSMMMSYAAERSMMSSYERSMMSYERSMMSPMAERSMMSAYERSMMSAYERSMMSPMAERSMMSAYERSMMSAYERSMMSPMADRSMMSMGADRSMMSSYSAADRSMMSSYSAADRSMMSSYTADRSMMSMAADSYTDSYTDTYTEAYMVPPLPPEEPPTMPPLPPEEPPMTPPLPPEEPPEGPALPTEQSALTAENTWPTEVPSSPSEESVSQPEPPVSQSEISEPSAVPTDYSVSASDPSVLVSEAAVTVPEPPPEPESSITLTPVESAVVAEEHEVVPERPVTCMVSETPAMSAEPTVLASEPPVMSETAETFDSMRASGHVASEVSTSLLVPAVTTPVLAESILEPPAMAAPESSAMAVLESSAVTVLESSTVTVLESSTVTVLEPSVVTVPEP--------------------------------------PVVAEPDYVTIPVPVVSALEPSVPVLEPAVSVLQPSMIVSEPSVSVQESTVTVSEPAVTVSEQTQVIPTEVAIESTPMILESSIMSSHVMKGINLSSGDQNLAPEIGMQEIALHSGEEPHAEEHLKGDFYESEHGINIDLNINNHLIAKEMEHNTVCAAGTSPVGEIGEEKILPTSETKQRTVLDTYPGVSEADAGETLSSTGPFALEPDATGTSKGIEFTTASTLSLVNKYDVDLSLTTQDTEHDMVISTSPSGGSEADIEGPLPAKDIHLDLPSNNNLVSKDTEEPLPVKESDQTLAALLSPKESSGGEKEVPPPPKETLPDSGFSANIEDINEADLVRPLLPKDMERLTSLRAGIEGPLLASDVGRDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGRSPKRLTDLDKAQLLEIAKAN-AAAMCAKAGVPLPPNLKPAPPPTIEEKVAKKSGGATIEELTEKCKQIAQSKEDDDVIVNKPHVSDEEEEEPPFYHHPFKLSEPKPIFFNLNIAAAKPTPPKSQVTLTKEFPVSSGSQHRKKEADSVYGEWVPVEKNGEENKDDDNVFSSNLPSEPVDISTAMSERALAQKRLSENAFDLEAMSMLNRAQERIDAWAQLNSIPGQFTGSTGVQVLTQEQLANTGAQAWIKKDQFLRAAPVTGGMGAVLMRKMGWREGEGLGKNKEGNKEPILVDFKTDRKGLVAVGER---------AQKRSGNFSAAMKD--------------------LSGKHPVSALMEICNKRRWQPPEFLLVHDSGPDHRKHFLFRVLRNGALTRPN----------------CMFFLNRY---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VHB0-1", "uniprot_id": "SON_DROME", "id": "Q9VHB0-1", "name": "Protein Son", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTENTEKGASVETPQVAGSQTNPPVQEPLALTKIPPIKVKSERPDAEVEAKLRAMNAKIKAEMVTLMRRSNSNELGNNDESG---------------------------ESESSASADDKKN---IKPVKSSNEILAELFGVFNAAPPEELLDDNLFKKKKKVKKEKKDKKAKKKKTTKS--------DGECSDSEAEGKHKHKRKKHKHKDIRVKDKEKDRDRDKSKEKDRDRVTDKSKE--------------------KDRDRDRDRDKSKDKFTAAQAPSEKEKEKSES------------------------------------------------------RKRSAVEPSSHSEKRERHEREKHRDWEREREREKEHERERVRSNNSFYNGQREADRLKGSESASTKSRQEQDLSDISLSDEESYLREKASNG---------------RRRAHNSFYDEKEELSVSPKRNVRESNTRRNRKSRSRSRDLGIDKKRLLEIARRNAINMFKQGTMPG-VANMTAEVKDKVLVKMRYGGRTIQDLTDFCKKIS---------------NGDGLSDLSSEEESDVDKNGNAKVFHHPFQLKE----------REPIVMHIRNSTALVPAPPRLDEQTKAITMQFPVSSGQTHRNNEVWVPVDPKDSLVPLPSLPP-----------------AKQATNMFKETPKNVFAKSIPLQEQQEP-----AFKPLGGAVVVPPLAATQLPTVPQSVPPTVPKEFAPPAVP----------FVPEVPIPSTSPVTPMQSASIFPDVTPPSMDVSSIITQRLSAIRRLQENPADSEALKMMYTAQRNMSSWANSKHLPGQFTGSTGAQVMKAHELN-SGPQLWVRKDQMTSTKPVTGGMGMALLQKMGWKPGEGLGRCKTGSLQPLLLDVKLDKRGLVSRDDLRPPQMRAPAAQRRNKNMAGPIGAGPCPAVQGAGPGPLASTPLVTQDKHPVCVLNELTSKNKWMPPQYKLRQDIGPAHNRSFLFSVEINGQTFTPDRGSNNKKEAKLNAAALCLRSLGILPPS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * ..** * : *:. .:**. . .. *.: *... * :.: :.:.::: .. * ..::: . * * . . * . * * . . * .. *::* . *: : . .:*. .: .* * :.. * .: *: :. . :* ::* ... . :: . * ** : .:* : .:. :*.*.. ..* *.:*...* * .. * ..... : * : :. :*: :.*:. :*::* .* .. .* *.:*:..:. * *:..* *:::*:. ***: .* ..: . *** ::. *..: * : :.*.*.*. . *::: . *.. . :. * . . :. : .. :. .** . : .: * . . * .*... . . . .. *.:*:. *.** : .*: :* ** : ** :::. :. : :. **: *: . .* *:: .** :: :: * :. :*::** .** :. * : ..* . *:.***. .: . : **: ... . :. : ..:.. .:*:*: :::* * :**.**. * **:.*: **..:.:**: : :*********.**:. .:* :*.* *::***: : ******* .*::****: *****: * *. :*:*:*.* *::***: .: **:*. *::..: ..****..* *: .*.:* **:: * :* ** *.: *** * ** *: *: *. ", "identical_positions": 194, "similar_positions": 315, "identity": "7.72%" }, { "cls_id": "homologset.agr.RGD:1309015", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "F1M987-1", "uniprot_id": "F1M987_RAT", "id": "F1M987-1", "name": "Signal peptide, CUB and EGF-like domain-containing protein 1", "aln": "MGAAAVRWHLCLLLALGARGQLVGGSGLPGAVDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGKQCEDIDECENDYYNGGCVHDCINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDCTLTCNYGNGGCQHSCEDTDTGPMCGCHQKYALHADGRTCIEKDEAAIERSQFNATSVADVDKRVKRRLLMETCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCKDINECLMNNGGCDHFCRNTVGSFECGCQKGHKLLTDERTCQDIDECSFERTCDHICINSPGSFQCLCHRGYILYGTTHCGDVDECSMNNGSCDQGCVNTKGSYECVCPPGRRLHWNRKDCVEMSGCLSRSKASAQAQLSCGKVGGVENCFLSCLGQSLFMPDSETSYILSCGVPGLQGKAPPKRNGTSSSVG--PGCSDAPTTPIRQKARFKIRDAKCHLRPRSQERAKDTLRH-------PLLDNCHVTFVTLKCDSSKKRRRGRKSPSKEVSHITAEFEVEMKVEEASGSCEADCMRKRAEQSLQAAIKTLRKSIGRHQFYVQVSGTEYEVAQRPAK-APEGTGTCGIGQILQDGKCVPCAPGTYFSSEPGQCVPCVSGTYQDMEGQLSCTPCPSSEGLGLAGARNVSECGGQCSPGFFSEDGFKPCQACPVGTYQPEPGRTGCFPCGGGLLTKQTGTASFQECEAKVHCSPGHHYNTTTHRCIRCPVGTYQPEFGQNHCISCPGNTSTDFDGSTNVTHCKNQHCGGELGDYTGYIESPNYPGDYPANAECVWHIAPPPKRRILIVVPEIFLPIEDECGDVLVMRKSASPTSVTTYETCQTYERPIAFTSRSRKLWIQFKSNEANSGKGFQVPYVTYDEDYQQLIEDIVRDGRLYASENHQEILKDKKLIKALFDVLAHPQNYFKYTAQESKEMFPRSFIKLLRSKVSRFLRPYK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6NZL8-1", "uniprot_id": "SCUB1_MOUSE", "id": "Q6NZL8-1", "name": "Signal peptide, CUB and EGF-like domain-containing protein 1", "aln": "MGAAAVRWHLYLLLALGARGRLVGGSGLPGAVDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGRQCEDIDECENDYYNGGCVHDCINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDCTLTCNYGNGGCQHSCEDTDTGPMCGCHQKYALHADGRTCIEKDEAAIERSQFNATSVADVDKRVKRRLLMETCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCKDINECLMNNGGCDHFCRNTVGSFECGCQKGHKLLTDERTCQDIDECSFERTCDHICINSPGSFQCLCRRGYTLYGTTHCGDVDECSMNNGSCEQGCVNTKGSYECVCPPGRRLHWNQKDCVEMNGCLSRSKASAQAQLSCGKVGGVENCFLSCLGHSLFMPDSESSYILSCGVPGLQGKTLPKRNGTSSSTG--PGCSDAPTTPIRQKARFKIRDAKCHLQPRSQERAKDTLRH-------PLLDNCHVTFVTLKCDSSKKRRRGRKSPSKEVSHITAEFEVEMKVDEASGTCEADCMRKRAEQSLQAAIKILRKSIGRNQFYVQVLGTEYEVAQRPAK-ALEGTGTCGIGQILQDGKCVPCAPGTYFSGDPGQCMPCVSGTYQDMEGQLSCTPCPSSEGLGLAGARNVSECGGQCSPGYFSADGFKPCQACPVGTYQPEPGRTGCFPCGGGLLTKHTGTASFQDCEAKVHCSPGHHYNTTTHRCIRCPVGTYQPEFGQNHCISCPGNTSTDFDGSTNVTHCKNQHCGGELGDYTGYIESPNYPGDYPANAECVWHIAPPPKRRILIVVPEIFLPIEDECGDVLVMRKSASPTSVTTYETCQTYERPIAFTSRSRKLWIQFKSNEANSGKGFQVPYVTYDEDYQQLIEDIVRDGRLYASENHQEILKDKKLIKALFDVLAHPQNYFKYTAQESKEMFPRSFIKLLRSKVSRFLRPYK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IWY4-1", "uniprot_id": "SCUB1_HUMAN", "id": "Q8IWY4-1", "name": "Signal peptide, CUB and EGF-like domain-containing protein 1", "aln": "MGAAAVRWHLCVLLALGTRGRLAGGSGLPGSVDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGKQCEDIDECENDYYNGGCVHECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDCTLTCNYGNGGCQHSCEDTDTGPTCGCHQKYALHSDGRTCIE------------------------------TCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCKDINECLVNNGGCDHFCRNTVGSFECGCRKGYKLLTDERTCQDIDECSFERTCDHICINSPGSFQCLCHRGYILYGTTHCGDVDECSMSNGSCDQGCVNTKGSYECVCPPGRRLHWNGKDCVETGKCLSRAKTSPRAQLSCSKAGGVESCFLSCPAHTLFVPDSENSYVLSCGVPGPQGKALQKRNGTSSGLG--PSCSDAPTTPIKQKARFKIRDAKCHLRPHSQARAKETARQ-------PLLDHCHVTFVTLKCDSSKKRRRGRKSPSKEVSHITAEFEIETKMEEASDTCEADCLRKRAEQSLQAAIKTLRKSIGRQQFYVQVSGTEYEVAQRPAK-ALEGQGACGAGQVLQDSKCVACGPGTHFGGELGQCVSCMPGTYQDMEGQLSCTPCPSSDGLGLPGARNVSECGGQCSPGFFSADGFKPCQACPVGTYQPEPGRTGCFPCGGGLLTKHEGTTSFQDCEAKVHCSPGHHYNTTTHRCIRCPVGTYQPEFGQNHCITCPGNTSTDFDGSTNVTHCKNQHCGGELGDYTGYIESPNYPGDYPANAECVWHIAPPPKRRILIVVPEIFLPIEDECGDVLVMRKSASPTSITTYETCQTYERPIAFTSRSRKLWIQFKSNEGNSGKGFQVPYVTYDEDYQQLIEDIVRDGRLYASENHQEILKDKKLIKALFDVLAHPQNYFKYTAQESKEMFPRSFIKLLRSKVSRFLRPYK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PAA2-1", "uniprot_id": "A0A8M1PAA2_DANRE", "id": "A0A8M1PAA2-1", "name": "Signal peptide, CUB and EGF-like domain-containing protein 1", "aln": "MGPACFSWEVCLLFLLINTLDVMGNVGVP---DADECSEATDDCHIDALCQNTPKSFKCICKTGYKGDGKHCEDIDECEND-YNGGCVHDCINIPGNYRCTCYDGFMLADDGHNCLDVDECLDNNGGCQQICVNTMGSYECQCKDGFFLSDNQHTCIHRSDDGMNCMNKDHGCAHICREITKGGVACECRPGFELAENQRDCKLTCNYGNGGCQHTCDDTDVGPICGCHQKYALHSDSKTCIEKDEAAIESSEFNTTSVADVDKRVKRRLLMETCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCKDIDECLENNGGCDHFCRNTVGSFECSCQKGHKLLTNERTCQDIDECSFERTCDHVCINYPGSFECVCHKGYSLYGFTHCGDIDECSINNGSCEHGCVNTPGSYECVCPPGQKLHWNKKDCVEAVKCLQNGKPPPRAQLSCTKTGGGEVCSLSCPSNALFLADSENSYTLSCGVPVQPGKAPLKRNITTSSSSSLQTCTEMLAQPVKQKARFKIKDAKCHMRPRNKEKHRDMGKQGLQAGQFPCTDDCQVTFVNLKCDSSKKRRRGRKSPSKEVSHITAEFEMEMKEEEASESCNLDCVREKTKQRLQNAMRTLRKSISKQQFYIQFSGTAYEVAQHALRHTTEGDETCSIGQVFTDGKCVSCVVGTFYSGEQEQCVMCPLGTYQDREGQLSCEPCPRTEGQGIAGAKNVSECGGQCPAGQFSSDGFRPCQPCQLGTFQPEPGRVLCFPCGGGLMTKHTGSTSFRDCEAKVHCALGHYYNATTHRCIRCPAGTYQSESGQNYCITCPGNTTTDFDGANNVSHCKNQICGGELGDFMGYIESPNYPGDYPSNVDCVWTINPPNKRRILIVVPEIFLPIEDECGDVLVMRKSALPTSITTYETCQTYERPIAFTSRSRKLWIQFKSNEGNSGKGFQVPYVTYDEDYQQLIEDIVRDGRLYASENHQEILKDKKLIKALFDVLAHPQNYFKYTVQESKEMFPRSFIKLLRSKVSRFLRPYK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.*.. *.: :*: * : *. *:* *.*****.********:*******:**:**.****:*::********** *******:************:******.*********** ************:********:.***************::***************** .******:*****:**:**:**.************:*:***.** **********:*.:**** ****************************************:*** ******************.*:**:****:******************:*** ****:*:*::** *** *****:****:.****::***** **********::**** ***** **...*...:***** *.** * * *** .::**:.***.** ****** **: *** *:*. . *:: : *::*******:*****::*:.: : :: :: * *.*:****.****************************:* * :*** :*: **:*::::* ** *:: *****.::***:*. ** *****:. : : ** :*. **:: *.***.* **.:..: **: * ***** ****** *** ::* *:.**:*********..* ** ***:***.* :**:******. ********:**: *::**::*******: **:**:*********.****.* ***:**:*****:*****:.**:***** *******: *************:*.:*** * ** ***************************** ***:******************************.***************************************************************.***************************", "identical_positions": 738, "similar_positions": 161, "identity": "71.79%" }, { "cls_id": "homologset.agr.RGD:1309016", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5PPH0-1", "uniprot_id": "ENOPH_RAT", "id": "Q5PPH0-1", "name": "Enolase-phosphatase E1", "aln": "MVVVSVPAEVTVILLDIEGTTTPIAFVKDILFPYIKENVKEYLQTHWEEEECQQDVSLLRKQAEEDAHLDGAVPIPVASGG---DVQQMIQAVVDNVSWQMSHDRKTTALKQLQGHMWKAAFTAGRMKAEVFADVVPAVRRWREAGMKVYIYSSGSVEAQKLLFGHSTEG--------DILELIDGHFDTKIG-HKVESDSYRKIADSIGCSTNNILFLTDVTVEASAAEEADVHVAVVVRPGNAGLTDDEKTYYNLISSFS---ELYLPSTQSKV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BGB7-1", "uniprot_id": "ENOPH_MOUSE", "id": "Q8BGB7-1", "name": "Enolase-phosphatase E1", "aln": "MVVVSVPAEVTVILLDIEGTTTPIAFVKDVLFPYIKENVKEYLQTHWEEEECQQDVSLLRKQAEEDAHLDGAVPIPVASGS---DLQQMIQAVVDNVYWQMSHDRKTTALKQLQGHMWKAAFTAGRMKAEFFADVVPAVRRWREAGMKVYIYSSGSVEAQKLLFGHSTEG--------DILELIDGHFDTKIG-HKVDSESYRKIADSIGCSTNNILFLTDVTVEASAAEEADVHVAVVVRPGNAGLTDDEKTYYNLITSFS---ELYLPST----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UHY7-1", "uniprot_id": "ENOPH_HUMAN", "id": "Q9UHY7-1", "name": "Enolase-phosphatase E1", "aln": "MVVLSVPAEVTVILLDIEGTTTPIAFVKDILFPYIEENVKEYLQTHWEEEECQQDVSLLRKQAEEDAHLDGAVPIPAASGNGVDDLQQMIQAVVDNVCWQMSLDRKTTALKQLQGHMWRAAFTAGRMKAEFFADVVPAVRKWREAGMKVYIYSSGSVEAQKLLFGHSTEG--------DILELVDGHFDTKIG-HKVESESYRKIADSIGCSTNNILFLTDVTREASAAEEADVHVAVVVRPGNAGLTDDEKTYYSLITSFS---ELYLPSST---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6GMI7-1", "uniprot_id": "ENOPH_DANRE", "id": "Q6GMI7-1", "name": "Enolase-phosphatase E1", "aln": "MAAIAIPENTRVFLLDIEGTTTPITFVKDILFPYIRENLEDYLSAHWEEDECKQDVHLLKKQTEEDLRQNKACHVHTVDQTVHTDEEKAIREVVENVLWQMAADRKTTALKQLQGHMWRAAYMMGRIKGEVYQDVVPAIRRWRHHGLKIYIYSSGSVEAQKLLFGYSVQG--------DILDLFDGHFDTNIG-AKVESKSYENIAERIGCQPEEIMFLTDVTREAKAAEDAGVNVAVVVRPGNMELTEEERDHYRIITSFN---QLELIGNV---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VN95-1", "uniprot_id": "ENOPH_DROME", "id": "Q9VN95-1", "name": "Enolase-phosphatase E1", "aln": "--MSSSERVAKVVLVDIEGTTTSISFVHDVLFPYAKQNVEKFLRDSWEEDDIKRIVQDLQQVPQYADYK------ALLSGP---PTEVDVDLIAGFVRYLIDQDLKVTPMKTLQGLIWAQGYANGELKGHVYEDVPAAFEAWRAAGLQIAVYSSGSVAAQKLIFGHSLAG--------NLQPYLSAYFDTHVG-HKQEQQSYKNIAKQLKEDPKQILFLTDIPGEAAAARCAGLQAIILKRPGNAALADDQKTGFELIPDFKPLHNLKVPVNKSQA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32626-1", "uniprot_id": "ENOPH_YEAST", "id": "P32626-1", "name": "Enolase-phosphatase E1", "aln": "-----MGDNYSTYLLDIEGTVCPISFVKETLFPYFTNKVPQLVQQDTRDSPVSNILSQFHIDNKE--------------------------QLQAHILELVAKDVKDPILKQLQGYVWAHGYESGQIKAPVYADAIDFIKRK----KRVFIYSSGSVKAQKLLFGYVQDPNAPAHDSLDLNSYIDGYFDINTSGKKTETQSYANILRDIGAKASEVLFLSDNPLELDAAAGVGIATGLASRPGNAPVPDGQK--YQVYKNFETL------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *:*****. .*:**:: **** ::: . : .:. .. : :: : : : : * * . :* *** :* .: *.:*. .: *. .. :: :****** ****:**: :: ...:** : . * : .** :* : ...:::**:* . * ** ..: . : **** :.: :: : : .*. ", "identical_positions": 52, "similar_positions": 76, "identity": "18.84%" }, { "cls_id": "homologset.agr.RGD:1309017", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q641Z6-1", "uniprot_id": "EHD1_RAT", "id": "Q641Z6-1", "name": "EH domain-containing protein 1", "aln": "MFSWVSKDARRKKEPELFQTVAEGLRQLYAQKLLPLEEHYRFHEFHSPALEDADFDNKPMVLLVGQYSTGKTTFIRHLIEQDFPGMRIGPEPTTDSFIAVMHGPTEGVVPGNALVVDPRRPFRKLNAFGNAFLNRFMCAQLPNPVLDSISIIDTPGILSGEKQRISRGYDFAAVLEWFAERVDRIILLFDAHKLDISDEFSEVIKALKNHEDKIRVVLNKADQIETQQLMRVYGALMWSLGKIINTPEVVRVYIGSFWSHPLLIPDNRKLFEAEEQDLFKDIQSLPRNAALRKLNDLIKRARLAKVHAYIISSLKKEMPNVFGKESKKKELVNNLGEIYQKIEREHQISSGDFPSLRKMQELLQTQDFSKFQALKPKLLDTVDDMLANDIARLMVMVRQEESLMPSQAVKGGAFDGTMNGPFGHGYGEGAGEGIDDVEWVVGKDKPTYDEIFYTLSPVNGKITGANAKKEMVKSKLPNTVLGKIWKLADVDKDGLLDDEEFALANHLIKVKLEGHELPADLPPHLIPPSKRRHE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WVK4-1", "uniprot_id": "EHD1_MOUSE", "id": "Q9WVK4-1", "name": "EH domain-containing protein 1", "aln": "MFSWVSKDARRKKEPELFQTVAEGLRQLYAQKLLPLEEHYRFHEFHSPALEDADFDNKPMVLLVGQYSTGKTTFIRHLIEQDFPGMRIGPEPTTDSFIAVMHGPTEGVVPGNALVVDPRRPFRKLNAFGNAFLNRFMCAQLPNPVLDSISIIDTPGILSGEKQRISRGYDFAAVLEWFAERVDRIILLFDAHKLDISDEFSEVIKALKNHEDKIRVVLNKADQIETQQLMRVYGALMWSLGKIINTPEVVRVYIGSFWSHPLLIPDNRKLFEAEEQDLFKDIQSLPRNAALRKLNDLIKRARLAKVHAYIISSLKKEMPNVFGKESKKKELVNNLGEIYQKIEREHQISSGDFPSLRKMQELLQTQDFSKFQALKPKLLDTVDDMLANDIARLMVMVRQEESLMPSQAVKGGAFDGTMNGPFGHGYGEGAGEGIDDVEWVVGKDKPTYDEIFYTLSPVNGKITGANAKKEMVKSKLPNTVLGKIWKLADVDKDGLLDDEEFALANHLIKVKLEGHELPADLPPHLIPPSKRRHE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H4M9-1", "uniprot_id": "EHD1_HUMAN", "id": "Q9H4M9-1", "name": "EH domain-containing protein 1", "aln": "MFSWVSKDARRKKEPELFQTVAEGLRQLYAQKLLPLEEHYRFHEFHSPALEDADFDNKPMVLLVGQYSTGKTTFIRHLIEQDFPGMRIGPEPTTDSFIAVMHGPTEGVVPGNALVVDPRRPFRKLNAFGNAFLNRFMCAQLPNPVLDSISIIDTPGILSGEKQRISRGYDFAAVLEWFAERVDRIILLFDAHKLDISDEFSEVIKALKNHEDKIRVVLNKADQIETQQLMRVYGALMWSLGKIINTPEVVRVYIGSFWSHPLLIPDNRKLFEAEEQDLFKDIQSLPRNAALRKLNDLIKRARLAKVHAYIISSLKKEMPNVFGKESKKKELVNNLGEIYQKIEREHQISPGDFPSLRKMQELLQTQDFSKFQALKPKLLDTVDDMLANDIARLMVMVRQEESLMPSQVVKGGAFDGTMNGPFGHGYGEGAGEGIDDVEWVVGKDKPTYDEIFYTLSPVNGKITGANAKKEMVKSKLPNTVLGKIWKLADVDKDGLLDDEEFALANHLIKVKLEGHELPADLPPHLVPPSKRRHE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*************************************************************************************************************************************************************************************************************************************************************************************************************************************************************.*********************************************************.*********************************************************************************************************************:********", "identical_positions": 531, "similar_positions": 3, "identity": "99.44%" }, { "cls_id": "homologset.agr.RGD:1309018", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q4G061-1", "uniprot_id": "EIF3B_RAT", "id": "Q4G061-1", "name": "Eukaryotic translation initiation factor 3 subunit B", "aln": "MQDAENVAAPEAAEERAEPARQQPVSESPPTD---EAAGSGGSEVGRTEDAEEDA---EARPEPEVRAKPAAQSEEETAASPAASPTPQSAQ-----EPSAPGKAEAGGEQAR-HPSAR-----AEEEGGSDGSAAEAEPRALENGEADEPSFSDPEDFVDDVSEEELLGDVLKDRPQEADGIDSVIVVDNVPQVGPDRLEKLKNVIHKIFSKFGKIINDYYPE--EDGKTKGYIFLEYASPAHAVDAVKNADGYKLDKQHTFRVNLFTDFDKYMT--ISDEWDIPEKQPFKDLGNLRYWLEEAECRDQYSVIFESGD---RTSIFWNDVKDPVSIEERARWTETYVRWSPKGTYLATFHQRGIALWGGDKFKQIQRFSHQGVQLIDFSPCERYLVTFS------------PLMDTQDDPQAIIIWDILTGHKKRGFHCESS--AHWPIFKWSHDGKFFARMTLDTLSIYETPS-MGLLDKKSLKISGIKDFSWSPG-------------GNIIAFWVPEDKDIPARVTLMQLPTRQEIRVRNLFNVVDCKLHWQKNGDYLCVKVDRTPKGTQ----------GVVTNFEIFRMREKQVPVDVVEMKETIIAFAWEPNGSKFAVLHG--------EAPRISVSFYHVKSNGK------IELIKMFDKQQANTIFWSPQGQFVVLAGLRSM---NGALAFVDTS---------------DCTVMNIAEHYMASDVEWDPTGRYVVTSVSWWSHKVDNAYWLWTFQGRLLQKNNKDRFCQLLWRPRPPTLLSQDQIKQIKKDLKKYSKIFEQKDRLSQSKASKELVERRRTMMEDFRQYRKMAQELYMKQKNERLELRGGVDTDELDSNVDDWEEETIEFFVTEEVIPLGSQE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8JZQ9-1", "uniprot_id": "EIF3B_MOUSE", "id": "Q8JZQ9-1", "name": "Eukaryotic translation initiation factor 3 subunit B", "aln": "MQDAENVAVPEAAEERAEPARQQPASESPPTD---EAAGSGGSEVGQTEDAEEDA---EAGPEPEVRAKPAAQSEEETATSPAASPTPQSAERSPSQEPSAPGKAEAVGEQARGHPSAG-----AEEEGGSDGSAAEAEPRALENGEADEPSFSDPEDFVDDVSEEELLGDVLKDRPQEADGIDSVIVVDNVPQVGPDRLEKLKNVIHKIFSKFGKIINDYYPE--EDGKTKGYIFLEYASPAHAVDAVKNADGYKLDKQHTFRVNLFTDFDKYMT--ISDEWDIPEKQPFKDLGNLRYWLEEAECRDQYSVIFESGD---RTSIFWNDVKDPVSIEERARWTETYVRWSPKGTYLATFHQRGIALWGGDKFKQIQRFSHQGVQLIDFSPCERYLVTFS------------PLMDTQDDPQAIIIWDILTGHKKRGFHCESS--AHWPIFKWSHDGKFFARMTLDTLSIYETPS-MGLLDKKSLKISGIKDFSWSPG-------------GNIIAFWVPEDKDIPARVTLMQLPTRQEIRVRNLFNVVDCKLHWQKNGDYLCVKVDRTPKGTQ----------GVVTNFEIFRMREKQVPVDVVEMKETIIAFAWEPNGSKFAVLHG--------EAPRISVSFYHVKSNGK------IELIKMFDKQQANTIFWSPQGQFVVLAGLRSM---NGALAFVDTS---------------DCTVMNIAEHYMASDVEWDPTGRYVVTSVSWWSHKVDNAYWLWTFQGRLLQKNNKDRFCQLLWRPRPPTLLSQDQIKQIKKDLKKYSKIFEQKDRLSQSKASKELVERRRTMMEDFRQYRKMAQELYMKQKNERLELRGGVDTDELDSNVDDWEEETIEFFVTEEVIPLGSQE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P55884-1", "uniprot_id": "EIF3B_HUMAN", "id": "P55884-1", "name": "Eukaryotic translation initiation factor 3 subunit B", "aln": "MQDAENVAVPEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVSEDAGGNEGRAAEAEPRALENGDADEPSFSDPEDFVDDVSEEELLGDVLKDRPQEADGIDSVIVVDNVPQVGPDRLEKLKNVIHKIFSKFGKITNDFYPE--EDGKTKGYIFLEYASPAHAVDAVKNADGYKLDKQHTFRVNLFTDFDKYMT--ISDEWDIPEKQPFKDLGNLRYWLEEAECRDQYSVIFESGD---RTSIFWNDVKDPVSIEERARWTETYVRWSPKGTYLATFHQRGIALWGGEKFKQIQRFSHQGVQLIDFSPCERYLVTFS------------PLMDTQDDPQAIIIWDILTGHKKRGFHCESS--AHWPIFKWSHDGKFFARMTLDTLSIYETPS-MGLLDKKSLKISGIKDFSWSPG-------------GNIIAFWVPEDKDIPARVTLMQLPTRQEIRVRNLFNVVDCKLHWQKNGDYLCVKVDRTPKGTQ----------GVVTNFEIFRMREKQVPVDVVEMKETIIAFAWEPNGSKFAVLHG--------EAPRISVSFYHVKNNGK------IELIKMFDKQQANTIFWSPQGQFVVLAGLRSM---NGALAFVDTS---------------DCTVMNIAEHYMASDVEWDPTGRYVVTSVSWWSHKVDNAYWLWTFQGRLLQKNNKDRFCQLLWRPRPPTLLSQEQIKQIKKDLKKYSKIFEQKDRLSQSKASKELVERRRTMMEDFRKYRKMAQELYMEQKNERLELRGGVDTDELDSNVDDWEEETIEFFVTEEIIPLGNQE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q0E940-1", "uniprot_id": "EIF3B_DROME", "id": "Q0E940-1", "name": "Eukaryotic translation initiation factor 3 subunit B", "aln": "----------------------------------------------------------------------MAKKK-------------------------------------------------SEEHSGTDANDSDYQ---------EEPNFDDPPGFVDNISDEDLLGDMLAQRPSEADGVESVVVVDNIPKVEPVRLEKLKLVINKLFSNYGEIVNVVYPVD-EEGKTKGYAFMEYKQARQAEEAVKKLNNHRLDKNHTFAVNLFTDFQKYEN--IPEKWEPPTVQTFKVQSDLYNFINDPDTYDQYCVAAETAPNCVQVGFWQNVLPEPFELETRERFTDTFVKWSPLGTYVVTFHKPGVAIWGGSSFQKIQKFPHPGTQFVEFSPCENYLVTYG------------PTPTG----QKIIIWDIRTGAEKRSFVADGM--SVLSMFRWSHDDKFVARMGENSIHIYETPS-FYLLDLKSIKIPGIRGFSWSPT-------------DNVIAYWVEEQNQIPARVTLMEIPKKREIRNKNLFHVADCKLHWQKSGDYLCVKVDRYSKLKKDKKDLDVKFLGMFYNFEIFHMREKEIPVDSVEIRELILAFAWEPVGNKFSIIHG--------ETNSSNVSFYEVNKGVK------PSLVKRLEKKSCTHLFWSPRGQFIVMANLT-----MGTFEFVDSTN--------------DYIITASPDHFRASEVEWDPTGRYVVTGVSSWKVKEDTGFNMYTFQGRIIKRTILKNFVQFLWRPRPPTLLSEEKQKEIKKNLKKYYAAFEQKDRLRLTRASKELLEKRSQLRETFMEYRNKRIAEWAEQKSRRIMLRGHVDTDNLET--DEVDEEIVEFLVKEEVTLLE---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P06103-1", "uniprot_id": "EIF3B_YEAST", "id": "P06103-1", "name": "Eukaryotic translation initiation factor 3 subunit B", "aln": "--------------------------------------------------------------MKNFLPRTLKNIYELYFN----------------------------------------------NISVHSIVSRNTQLKRSKIIQMTTETFEDIKLEDIPVDDIDFSDLEEQYKVTEEFNFDQYIVVNGAPVIPSAKVPVLKKALTSLFSKAGKVVNMEFPIDEATGKTKGFLFVECGSMNDAKKIIKSFHGKRLDLKHRLFLYTMKDVERYNSDDFDTEFREPDMPTFVPSSSLKSWLMDDKVRDQFVLQDDVKTSVFWNSMFN---EEDSLVESRENWSTNYVRFSPKGTYLFSYHQQGVTAWGGPNFDRLRRFYHPDVRNSSVSPNEKYLVTFSTEPIIVEEDNEFSPFTKKNEGHQLCIWDIASGLLMATFPVIKSPYLKWPLVRWSYNDKYCARMVGDSLIVHDATKNFMPLEAKALKPSGIRDFSFAPEGVKLQPFRNGDEPSVLLAYWTPETNNSACTATIAEVPRGRVLKTVNLVQVSNVTLHWQNQAEFLCFNVERHTKSGK----------TQFSNLQICRLTERDIPVEKVELKDSVFEFGWEPHGNRFVTISVHEVADMNYAIPANTIRFYAPETKEKTDVIKRWSLVKEIPKTFANTVSWSPAGRFVVVGALVGPNMRRSDLQFYDMDYPGEKNINDNNDVSASLKDVAHPTYSAATNITWDPSGRYVTAWSSSLKHKVEHGYKIFNIAGNLVKEDIIAGFKNFAWRPRPASILSNAERKKVRKNLREWSAQFEEQDAMEADTAMRDLILHQRELLKQWTEYREKIGQEMEKSMNFKIFDVQPEDASDDFTTIEEIVEEVLEETKEKVE-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . . : : .*.* :.: :: . : * ..:. :**:. * : . :: ** .: .:**: *:: * :* *****: *:* . .* . :*. .. :** :* : : :.*.::* . : :: * .* ..* :: : . **: : : .:: : :* * .:: .:*::** ***: ::*: *:: *** .*.::::* * ..: ..** *.****:. . : : **** :* * .:.:**::.*: *** ::: ::::.. : *: *::* .**:.**::* . ::*:*. * :: .. .*: ::* : :: **.:* : .****:..::**.:*:* .* : . *::* :: *:::**: **::: :: *.*** *.:* : .: ** :. * .*:* : * .. : *** *:*:*:. * . : * * . . : *::: ***:****.: * . * : .: ::.: *.:::. * :: *****.::**: : *:::*:*::: **::* : * ::*: :: : : : :**: :. . :: *:.: : :: ** :* : ", "identical_positions": 153, "similar_positions": 254, "identity": "17.17%" }, { "cls_id": "homologset.agr.RGD:1309019", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8C2K5-1", "uniprot_id": "RASL3_MOUSE", "id": "Q8C2K5-1", "name": "RAS protein activator like-3", "aln": "MKPECGQTMFRTFWSRSRDSSAMDPPLQSEEDSQTQPSLPSPLTSYRWHTGGSGEKAAGGFRWGRFAGWGRALSHQEPMVNSQPAPRSLFRRVLSAPPKESRSNRLRFSKTLWGRHKNVAPLEPKPNPKAPEPELELVADPDLPVAQIPEPPTPDMPVWNIDGFT----LLEGKLVMLG-EEEGPRQIRVGSASSENSMQAALGNLKDAVRTPGKTEPEAAGSNQVHNVRKLLKRLKEKKRAKSELGAYTPRDGPPSALGSRESLATLS---ELDLGAERDVRVWPLHPSLLGEPYCFQVTWAG-GSLCFSCRSSAERDRWIEDLRRQFQPSQDNVERQEMWLTVWVHEAKGLPRATV--PGVRAELWLDGALLARTAPRAGPGQLFWAERFHFEALPPARRLSLRLRSAGPAGATVG--RVVLELDEVSIPR-APAAGLERWFPVLGAPAG--------------------AVLRARIRVRCLRVLPSERYKELAEFLTFHYARLCGALEPALSAQAK-----EELAAAMVRVLRATGRAQALVTDLGTAELARCGGR--------------EALLFRENTLATKAIDEYMKLVAQEYLQDTLGQVVRCLCASTEDCEVDPSKCPTP-------ELPKHQARLRDSCEEVFENIIHSYNCFPAELGSVFSSWREACKARGSEA---LGPRLVCASLFLRLLCPAILAPSLFGLAPEHPAPGPARTLTLIAKVIQNLANCAPFGEKEAYMAFMNSFLEDHGPAMQHFLDQVATVDADTTPS---GYQGSGDLALQLAVLHVQLCTIFAELDQKTQDSLEPLPTILRAIEEGRPVPVSVPMR-------------------------------------------LPRISTQVQSSFFSGEK---PGFLAPRDLPK---------------------------------------------HTPLISKSQSLRSFQGAGSWASR---------------------------------RPDEERPQRRP---------------------------------RPVLRTQSVPARRPTHRRPSAGSK--------------------------------PRPKGSLRMGPAPCGRAWTRASASLPRKP---------------------------------------------------------SVPWQRQMDQPG----DRYQTTGTHR-PVGKLAEIQCEVAIFR----------------EAQKALSLLVESLSTQVQALKEQQEHFRCQLQDLYSRLGAGISKLDSKGGLPSNGSHRLKS----------------------------LEQRLTEMECSQDQLRDSLQSLQLLSKTPGSRSQPLPLKAPCVNGADLSMGT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZWW3-1", "uniprot_id": "D3ZWW3_RAT", "id": "D3ZWW3-1", "name": "", "aln": "----------------------MDPPLQNE-DSQTQ---PSPLTSYRWHTGGRGEKIAGGFRWGRFAGWGRALSHQEPMVSSQPAPRSLFRRVLSAPPKESRPNRLRFSKSLWGRHKNVVPLEPKLNPKAPEPELELEGAPDLRAAHIPEPPAPDMPVWNIDGFA----LLEGRLVMLG-EEEGPRQIRMGSASSESSMQAALGNLKDPVRTPGKIEPEATGSNQVHNVRKLLKRLKEKKRAKSELGAHTPRDGPSSALGSRESLATLS---ELDLGVERDVRVWPLHPSLLGEPYCFQVTWAG-GSRCFSCRSSAERDRWIEDLRRQFQPSQDNVERQETWLTVWVHEAKGLPRAAA--PGVRAELWLDGALLARTAPRAGPDQLFWAERFHFEALPPARRLSLRLRGAGPAGATVG--RVVLELDEVSIPR-APAAGLERWFPVLGAPAG--------------------AVLRARIRVRCLRVLPSERYKELAEFLTFHYARLCMALEPALSAQAK-----EELAAAMVRVLRATGRAQALVTDLGTAELERCGGR--------------EALLFRENTLATKAIDEYMKLVAQEYLQETLGQVVRSLCASTEDCEVDPSKCPTP-------ELPKCQARLRSSCEEVFENIIHSYNYFPAELGTVFSNWREACKARGSEA---LGPRLVCASLFLRLLCPAILAPSLFGLAPEHPAPGPARTLTLIAKVIQNLANCAPFGEKEAYMVFMNSFLEDHGPAMRHFLDQVAMVDTDTTPS---GYQGSGDLALQLAVLHVQLCTIFAELDQKTRDSLEPLPTILQAIEEGRPVPVSVPMR-------------------------------------------LPLNTAHVQSSFSSGEK---PGFLAPRDLPK---------------------------------------------HTPLISKSQSLRSFQGAGSWARR---------------------------------RPDGERPQRRP---------------------------------RPVLRTQSVPARRPTHHRPAAGSK--------------------------------PRPKGSLRTGPATSGRAWARTSTSLPRKP---------------------------------------------------------SVPWQRQLDQPG----DRYQTPGTHR-PVGKLAEIQCEVAALR----------------EEQKALSHLVESLSTHIQALTEQQEQLRCQLQDLDSRLGAGISKLDSKGGLPSNGSLGLKS----------------------------LEHRMTEMECSQNQLRDTLQSLQLLSKTPGSRSQPPPLKAPCVNGADLSMGT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q86YV0-1", "uniprot_id": "RASL3_HUMAN", "id": "Q86YV0-1", "name": "RAS protein activator like-3", "aln": "----------------------MDPPSPSR-TSQTQPTATSPLTSYRWHTGGGGEKAAGGFRWGRFAGWGRALSHQEPMVSTQPAPRSIFRRVLSAPPKESRTSRLRLSKALWGRHKNPPP-EPDPEPEQEAPELEPEPELEPPTPQIPEAPTPNVPVWDIGGFT----LLDGKLVLLGGEEEGPRRPRVGSASSEGSIHVAMGNFRDPDRMPGKTEPETAGPNQVHNVRGLLKRLKEKKKARLE-----PRDGPPSALGSRESLATLS---ELDLGAERDVRIWPLHPSLLGEPHCFQVTWTG-GSRCFSCRSAAERDRWIEDLRRQFQPTQDNVEREETWLSVWVHEAKGLPRAAAGAPGVRAELWLDGALLARTAPRAGPGQLFWAERFHFEALPPARRLSLRLRGLGPGSAVLG--RVALALEELDAPR-APAAGLERWFPLLGAPAG--------------------AALRARIRARRLRVLPSERYKELAEFLTFHYARLCGALEPALPAQAK-----EELAAAMVRVLRATGRAQALVTDLGTAELARCGGR--------------EALLFRENTLATKAIDEYMKLVAQDYLQETLGQVVRRLCASTEDCEVDPSKCPAS-------ELPEHQARLRNSCEEVFETIIHSYDWFPAELGIVFSSWREACKERGSEV---LGPRLVCASLFLRLLCPAILAPSLFGLAPDHPAPGPARTLTLIAKVIQNLANRAPFGEKEAYMGFMNSFLEEHGPAMQCFLDQVAMVDVDAAPS---GYQGSGDLALQLAVLHAQLCTIFAELDQTTRDTLEPLPTILRAIEEGQPVLVSVPMR-------------------------------------------LPLPPAQVHSSLSAGEK---PGFLAPRDLPK---------------------------------------------HTPLISKSQSLRSVRRSESWARP---------------------------------RPDEERPLRRP---------------------------------RPVQRTQSVPVRRPARRRQSAGPW--------------------------------PRPKGSLSMGPAPRARPWTRDSASLPRKP---------------------------------------------------------SVPWQRQMDQPQ----DRNQALGTHR-PVNKLAELQCEVAALR----------------EEQKVLSRLVESLSTQIRALTEQQEQLRGQLQDLDSRLRAGSSEFDSEHNLTSNEGHSLKN----------------------------LEHRLNEMERTQAQLRDAVQSLQLSPRTRGSWSQPQPLKAPCLNGDTT-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8T498-1", "uniprot_id": "GAP2_DROME", "id": "Q8T498-1", "name": "Ras GTPase-activating protein raskol", "aln": "----------------------MGRRTYLSRSSTISYPSRIEGWLDVCETEGELTRLIKTLPWG--PLYCVLQQDDQTFTAYCSEEISLGDVCYEDIPRVRLDRVRRPAKALWDGPPTLVEENEDSDSCVGGS----GGMSGINDIVLNTTLYSELGEYKSKTLP----RIHFDTALNDTSLNEDTSYEKACRRGSAPTTPILG----SKQHQTEHNATSRFTNFFSKKSNPLKRTKSVTKLERTKRGSGGLRGSRSHESLLSSHAVMS---TIDLSCTGAVGVAPVHQSVLGRRHCFQVRGGPRGERYYSCGSRQERDLWIYSLRKSIAPNAEHTRRTDNSLKMWVYEAKNLPPKKR----YFCELQLDKTLYGRTSVKLQTDLLFWGEHFDFPDIPEINVITVNVFREVDKKKKRDKYQFVGSVKIPVHDV-TSRLPCEQWYPILSDKAGDSLGRTSGGGGSGSKDKEQLPTLRIKCRFQSTDILPINVYGNFLTYLKENYKRVCETLEPVIGVKAK-----EDIGQALVLLMHAQGLAGAFLTDVVALDLLRVGD---------------QRLTFRGNSLATKSMEAFLKLTGEQYLQDTLSAPINELIQSERDCEVDPTKTSGSS----AGSLQRQQAALRGAVRGAWQCIFESHKHFPAQLRNCFATFRERLQQLGRQD---MADNLISASIFLRFLCPAILSPSLFNITSELPSARATRNLTLVAKTLQTLANFTRFQGKENFMEFLNDFLEQEAARMQQFLEIISTRPEHPAPDSILDWAGYIDQGKQLSILHSLLSESLAKLPEARQHELDPLQHILDEISRAKEHGMGTALPGGYLPATSSTHSIASENQENRNPGSSGSHAGSNSEQLLPQQSQLAQPQHAIVSKPLSAERGIMRGVLTPNSLEKNIFRYNDPTVNGLLQQQQQQQQQQQQQQQQHQQLQQHGHQQQPHHQHPLQMLSNSQTSIAGNQYMSSPGGLQHAQSQTSMASSSLNGSSSNLLHGHQQHAHHPQQLHPHHCPPAPQTSASSTMERMDRMNYPYMSHNGNDYETSTPSSTRSRTLPRNGNPNANGNVGSSNNNQSGSYDDMHGEFQIQISGFDTSSAFVCKSPTPMMKSSLGPAGAGRSHHKLNLGIPDHSGGYVRGNNLNPNSNMPKNLEDLDDLFKYAEEHDVAEPANHHNHNQGQQNHQGHLKPAAVPGKEQLSAKSSHCSSGYQSISTNPSPSQSSSPVESQLKAAMGSHNAPLAFKNPSYQLQPQTGSSRSSAQSNTHQQQQQQQQQQFGSRLKPIGGGLVAARAAFLNSGGALEAATLTPSSSDEQLSADNYFSYAAAAAAGAGIATKLEAQRSLSGGSSSSTSASASTSNLGKSGGSSAYGRLNGPLKREDVYGSGYGGSSGNVGYGLSTSSAAGHHQHPHQQQQNPMQQQQQRERDQEHKQYAGSVAGSVGSATSAAQRRLSLDSARTLSDSSTDTEGHCNQLQEGKRRRQLRSSGGSGGGGAGSEQGLGKSYDQNGEIQLLQQTLDTLCHTLDRDEAELRDSSDELFGLQRPAGSNGSNNLSLQSESTMRSIIDRLITMEEELRREQLKMSLALSHKQRVIEEQGQQIAALDAANSRLLSALTALRQRYETQQQQQQHQAPPKTQKPQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P33314-1", "uniprot_id": "BUD2_YEAST", "id": "P33314-1", "name": "Inhibitory regulator protein BUD2/CLA2", "aln": "--MSSNNEPAQSRTSYFKLNEFLSNVKHYKNTFKGEIQWCNNLSLNDWKTHYLQITSTGALTHSIDELTADSTNIQPIIKHLQQCRIEIIKDKHSSFKDINANCNFIIQVNTSGKDNKVYLRVKSWSDFKKLLTCLIWWSSMKTNGIFNKFQVSRPLEFKSKKMAKPESLLVYKLNVFGPIVKNIVLPPATNILESPDIINNDDNSVGWFSAMGVLKSNGMLDLLLQSDGSLIYSLNISQLLRSEIRILDSSVLQSENSLFLGELPLLRSQLGLEKFRIENIASAATNSSDISQEIIVEFPLRIDLEDCFIALQSFARSEYLSITGSDKSNDMKISNSFKISILEANFQSINLNDKNNTPWSIFTDITAWGHTWARTSMVSNSSNPFWREEFQFNELLRLTNSYLEIKQLFHDLNNKKRLRLIGKIKITQEIINDTRYNKETRLPIMDVDNKN----------------FQIGTICIKISSNLNFILPSTNFVKLEKLLMNANLSMVSNLIYKSSSSMENDNKLTQTSIIFLDIFQSLSRIEEWFHVLIDKELAKIDGTVSRINQKNLDSKHVFNSLFRGNSILTKSIEQYFFRVGNEYLSKALSAILKEIIESNKSCELDPARVKEKDEVKKRKIIADNYKRLYSWVTKIWKRLYATSNDLPIEIRNVLKIFRQKLEIICIDDTLQIILNGISGLLFLRFFCPVILNPKLFKYVSQNLNETARRNLTLISKVLLNLSTLTQFANKEPWLMKMNNFIDKRHNDLLDYIDKMTQKKLDFNSK--------------ILNLSSTISRPKLAIEQTMLDDLPQIPYLLDKNLRETEFVNLIVN--------------------------------------------FSQEDMTKMEKYNHMDNGGKGELIEEEGLLS----------------------------------------------------GSSLNLSVDKKDLDSP-----------------------------------IEVKPEIGE------------------------------------LEFEKITENNTEIFGDDLMNLLK------------------------------SDDVGSRSRDLDNGANSGIKFNSIIPKAE--------------------------------------------------------EEKHAMKELEQES---CLLYNRINHIR---KRLSGYECASSTLFE-----------------DKKYSISLSHKIFYEEIKEGKEIVLKLLNKPTNENSSARLQKFFTKGVSSKSNNTVGDS-----------------------------YCKFLTIDVSDENPKSSNK-TSVHGTSSENGAKDDYLTLPNSQGKGNLGNRFSPTKLSRIMRKPPNADVPKEQNSRKLTRWFKKKKETGGS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . .* : . . : : .: . . . . . : . :. :. : : . : . . :. . . : : . . . . : :: : . : * :.. .:. . : . . *. :: . . . . : .:: .* :: .**: .. ** *.*.* : :.: :. :. . * *::. .: : . :** : :: * : * . : : . :: :::: . . : :* : .. ** *:: **::: :: ..::**..:*. :. : * ..**:**:: : * . :: : : . :* :: : :*: : : : . :.. :***::**.** *.** ..: . *.***::*.: .*:. : * ** :: :*.*::.. : ::: :: . .. : * :. : : . * : :* . :. .. :. .: ..* . ..* :* . ..:. . . . . ... : . :* .::. : . : :. :. * . :: : : * : .. . .. : . :. . : . : *. * ", "identical_positions": 66, "similar_positions": 259, "identity": "4.0%" }, { "cls_id": "homologset.agr.RGD:1309020", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LNS5-1", "uniprot_id": "A0ABK0LNS5_RAT", "id": "A0ABK0LNS5-1", "name": "", "aln": "-MEAEPPP-LEERRRLQEELSEFVESCCRTLEEVTASLGWSLDHLDPGDEVTAEDEITICPYDSNHRMPKSSLPKHMESCRLRKLGYTKEEEDEMYNPTFFYENLKIPSVTLNKDSQFQIIKQARTTAGKDGDCYSQRLYSSAPVEVPLNHKRSVCDLTQADRLALYDFVIEETKKKRSAPQVIENDSDLFVDLAAKVNQDNSRKSPKSYLEILAEVRDYKRRRQSYRAKNVHITKKSYTEVIRDVIKVHMEELSNHWQEEQERAEDGAEKN------EERRSASVDSRQSGGSYLDVESSR-HRRARSRSPHKRKRNKDK--SSDSRRRKERRVCAPEYFIILALNSL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D361-1", "uniprot_id": "SNR48_MOUSE", "id": "Q9D361-1", "name": "U11/U12 small nuclear ribonucleoprotein 48 kDa protein", "aln": "-METEPPP-LEERRRLQEELSEFVESCCRTLEEVTASLGWSLDQLDPGDEAEAEDEIAICPYDSNHRMPKSSLTKHMESCRLRKLGYTKEEENEMYNPTFFYENLKIPSVTLNKDSQFQIIKQARTTAGKDGDCYSQRMYSSVPVEVPLNHKRSVCDLTQTDRLALYDFVIEETKKKRSGPQVIENDSDLFVDLAAKVNQDNSRKSPKSYLEILAEVRDYKRRRQSYRAKNVHITKKSYTEVIRDVIKVHMEELSSHWQEEQGRAGDAAEKN------EERRSASVDSRQSGGSYLDVESSR-HRRARSRSPHKRKRNKDK--SSESRRRKERDGERHHSHKRRKQKI-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6IEG0-1", "uniprot_id": "SNR48_HUMAN", "id": "Q6IEG0-1", "name": "U11/U12 small nuclear ribonucleoprotein 48 kDa protein", "aln": "-MEGEPPP-VEERRRLQEELNEFVESGCRTLEEVTASLGWDLDSLDPGEEEAAEDEVVICPYDSNHHMPKSSLAKHMASCRLRKMGYTKEEEDEMYNPEFFYENVKIPSITLNKDSQFQIIKQARTAVGKDSDCYNQRIYSSLPVEVPLNHKRFVCDLTQADRLALYDFVVEETKKKRSDSQIIENDSDLFVDLAAKINQDNSRKSPKSYLEILAEVRDYKRRRQSYRAKNVHITKKSYTEVIRDVINVHMEELSNHWQEEQEKAEDDAEKN------EERRSASVDSRQSGGSYLDAECSR-HRRDRSRSPHKRKRNKDKDKNCESRRRKERDGERHHSHKRRKQKI-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IMG9-1", "uniprot_id": "A0A0R4IMG9_DANRE", "id": "A0A0R4IMG9-1", "name": "", "aln": "MCETSFVSGLQERMQCLQELTDFTENCQAELKDLFEALGWK-QELD-----THAVQMEVCPYDPNHTVPQNKMEKHKAVCWLTQQGYSKEEQAEMYDPSAYYEQANITSISLEKDTFQQIILQSRENAS---HWRSTGLHTQSLPDIPQNHKRSLCDLTVADRLAVYDHVMYEASQQ--SAKRESNNEDLYVDLVAKIKKEVNQSGPKSHLEVLAEMRDYKRRRQSYRAKNVHITKKTYTEVIREVIDVHSGELGRIWQEAKEEESQVSQQSSHRAESEKGRSASVESRASRISSRDEHEHK-RHRKRSRS-RSRKHSREK--KKRSRRDSHSPDVERRHKKKKKNKS-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VWH9-1", "uniprot_id": "Q9VWH9_DROME", "id": "Q9VWH9-1", "name": "", "aln": "-MSGEDVD--EKR----EQLRLFVTASRRRLHVILQRFGWSERGVMGAGSHRPQDKNGATKSEVLEPLPLPASCSNNPDFSIQLDDSTIQGIVGTERARRLLPAASFDDLQAGLDASQRLLIY--EHVLKHTKKHPQFQDNTAFAEVVGETRR---QQKNHRRHRKSKPTLNEELHQLVSLQMQALEKQWEQEHGGRHHKQVDRQEHRGRYVEQSQQRTQTERQQDHKGRRDKPAERFQEHQWRHNEQTQHRQR---YQEDRGRHNDQMDRFK----EHKDRGQRQEHRDWRNERRDWYQHHDDSRKRSRSPSRHRHGDRR---REEREPREKQHNRHRSQTARH----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . ::* ::* *. *. : :**. : : : . :* .: : . : : . .: .: *: ::: . . . :: : :* : . * . .: * :: : :.: : .: ::: .:. :. :: * ..*:*.::.:. : ::: . *. ..: : :** : . : :: .: *. : * . * : * **** :::. : .*. . . ", "identical_positions": 26, "similar_positions": 102, "identity": "7.45%" }, { "cls_id": "homologset.agr.RGD:1309023", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4A2R5-1", "uniprot_id": "D4A2R5_RAT", "id": "D4A2R5-1", "name": "", "aln": "MPSGSSA--ALALAAAPAPLPQPPPLPP--------PAGGPELEGDGLLLRERLAALGLDDPSPAEPGAPALR----AAAAAAQCQARRAAGLAPEE---PGRLATSETAELELEVDEEEGEEAELDGELLEEEELEEAEEEDRPSLLLLSPPAATASQTQPIPGGPLGSVLLPAAGFDAREAAAAAA--GVLYGGDDAQGMMAAMLSHAYGPGGGGAAAAALNGEQAALLRRKSVNTTECVPVPSSEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEPIFVVTGRKEDVAMAKREILSAAEHFSMIRASR----------------NKNGPALGGLSCSPNLPGQTTVQVRVPYRVVGLVVGPKGATIKRIQQQTHTYIVTPSRDKEPVFEVTGMPENVDRAREEIEMHIAMRTGN-----------YIELNEENDFHYNGTDVSFEGGTLGSAWLS---SNPVPPSRARMMSNYRNDSSSS-----LGSGSTDSYFGSNRLADFSPTSPFSTGNFWFGDTLPSVGSEDLAVDSPAFDSLPTSAQTIWTPFEPVNPLSGFGSDPSGNMKTQRRGSQPSTPRLSPTFPESIEHPLARRVRS-------------DPPSTGNHVG-----------LPIYIPAFSNGTNSYSSS-------------------NGGSTSSSPPESRRKHDCVICFENEVIAALVPCGHNLFCMECANKICEKRTPSCPVCQTAVTQAIQIHS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q05A36-1", "uniprot_id": "MEX3C_MOUSE", "id": "Q05A36-1", "name": "RNA-binding E3 ubiquitin-protein ligase MEX3C", "aln": "MPSGSSAALALALAAAPAPLPQPPPLPPPP------PAGGPELEGDGLLLRERLAALGLDDPSPAEPGAPALRAAAVAAAAAAQCQARRATGLAPEE---PGRLATSETAELELEVDEEEGEEAELDGELLEEEELEEAEEEDRPSLLLLSPPAATASQTQPIPGGPLGSVLLPAAGFDAREAAAA----GVLYGGDDAQGMMAAMLSHAYGPGGGGAAAAALNGEQAALLRRKSVNTTECVPVPSSEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEPIFVVTGRKEDVAMAKREILSAAEHFSMIRASR----------------NKNGPALGGLSCSPNLPGQTTVQVRVPYRVVGLVVGPKGATIKRIQQQTHTYIVTPSRDKEPVFEVTGMPENVDRAREEIEMHIAMRTGN-----------YIELNEENDFHYNGTDVSFEGGTLGSAWLS---SNPVPPSRARMMSNYRNDSSSS-----LGSGSTDSYFGSNRLADFSPTSPFSTGNFWFGDTLPSVGSEDLTVDSPAFDSLPTSAQTIWTPFEPVNPLSGFGSDPSGNMKTQRRGSQPSTPRLSPTFPESIEHPLARRVRS-------------DPPSTGNHVG-----------LPIYIPAFSNGTNSYSSS-------------------NGGSTSSSPPESRRKHDCVICFENEVIAALVPCGHNLFCMECANKICEKRTPSCPVCQTAVTQAIQIHS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5U5Q3-1", "uniprot_id": "MEX3C_HUMAN", "id": "Q5U5Q3-1", "name": "RNA-binding E3 ubiquitin-protein ligase MEX3C", "aln": "MPSGSSA--ALALAAAPAPLPQPPPPPPPPPPPLPPPSGGPELEGDGLLLRERLAALGLDDPSPAEPGAPALR----APAAAAQGQARRAAELSPEERAPPGRPGAPEAAELELEEDEEEGEEAELDGDLLEEEELEEAEEEDRSSLLLLSPPAATASQTQQIPGGSLGSVLLPAARFDAREAAAAAAAAGVLYGGDDAQGMMAAMLSHAYGPGGCGAAAAALNGEQAALLRRKSVNTTECVPVPSSEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEPIFVVTGRKEDVAMAKREILSAAEHFSMIRASR----------------NKNGPALGGLSCSPNLPGQTTVQVRVPYRVVGLVVGPKGATIKRIQQQTHTYIVTPSRDKEPVFEVTGMPENVDRAREEIEMHIAMRTGN-----------YIELNEENDFHYNGTDVSFEGGTLGSAWLS---SNPVPPSRARMISNYRNDSSSS-----LGSGSTDSYFGSNRLADFSPTSPFSTGNFWFGDTLPSVGSEDLAVDSPAFDSLPTSAQTIWTPFEPVNPLSGFGSDPSGNMKTQRRGSQPSTPRLSPTFPESIEHPLARRVRS-------------DPPSTGNHVG-----------LPIYIPAFSNGTNSYSSS-------------------NGGSTSSSPPESRRKHDCVICFENEVIAALVPCGHNLFCMECANKICEKRTPSCPVCQTAVTQAIQIHS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V4F3-1", "uniprot_id": "Q9V4F3_DROME", "id": "Q9V4F3-1", "name": "RING-type domain-containing protein", "aln": "--------------------------------------------------------------------------------MAAQVTPKISTCINSKG----------------SIQKKNQAQHHDMSEQSKVNESTLPLSDDPRTLQLALELSLVGFNDNQNCYAQPAQPLPMPLS-----------------ARSDFEIGTINSTLPIPSAPN--CLLLPNAGAVSSEDRSKKSQNMTECVPVPSSEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEPVFVVTGRKEDVNKAKREILSAADHFSLIRASRKPVSDSQNNGMVGSTTSSGGGAVPRMSGPPCMPGQVTIQVRVPYRVVGLVVGPKGATIKHIQQETQTYIVTPSREKEPIFEVTGLPDNVDTARKQIEAHIALRTGSGSGSGDAITMQSSDSVDTKEYASLPSLTQILNDDLNSEILSSIYKNSVPSTQEYANNSMKTVVNVSNSVKLVQGHHTGNCFQKSEFAEMEMTANITAADILDKRLPGNEVSVPLAKANVANIVFRTTSSKTLSFCPPTSTSASFHSNCNANILTRSCSSASSTTSTKSTNNSANTPPEILNIWKSISDSIDVDEGIGDSPSIWNQPANIIPTAHCSPTISISPTDSLLGMGEHSANQQNLNHAKEPIMPNLPQKIKGIQVQSNADNFLTHRECFVCNENTVTTALVPCGHNMFCMECANHICLSMDAVCPVCNSIVYHAMRILG", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *** .: :: : .: .:::.:. ::. : :*. .:: *. * *. . . .:.* . . .: :* : .* * : : *. . .*. . .. .: :** * *******************************************:********** *********:***:***** ...* *: :* .* :***.*:*********************:***:*:********:***:*****:*:*** **::** ***:***. : : ::: : ..: .. *.* ** .*.**.:: .. :. . * : . *.. * ...:*::. *: :::.:: . * *: . * : *::.. : *... :.* *: ..*: *: .* .**. ..* .: * .: . *.** *: . :.* . * ..:*:. :* ...*.. : :::*.:* ** * :********:*******:** . . ****:: * :*::* .", "identical_positions": 213, "similar_positions": 175, "identity": "28.67%" }, { "cls_id": "homologset.agr.RGD:1309025", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z9K8-1", "uniprot_id": "D3Z9K8_RAT", "id": "D3Z9K8-1", "name": "Non-structural maintenance of chromosomes element 4", "aln": "--------MSGDSSGRRSEGRGRGRDPHRDRTRSRSRSR---SPLA---RRGAAPERREAAERPSLEDTEPSDSGDELMDPACLEAEYDQGLCRQIR----HQYRALINSVQQNREDILNAGDKLTEVLEEANTLFNEVSR--AREAVLDAQFLVLASDLGKEKAKQLRSDLS---SFDMLRYVETLLTHMGVNPLEAEEFIRD--EDRTDIELIVYDSWKISGKTAENTFNKTHTFHFLLGSIHGEFPVPKPRTDRPRQPRMIEEQRAMPAQLKCMEESHQEATEKEVERILGLLQTYFREDPDTPMSFFDFVVDPHSFPRTVENIFHVSFIIRDGFARIRLDQDRLPIIEPV--------INEESEGIDQNIQFRSQGIIALSYHDWEEIVKTFEISEPVISLSQSQQRLSA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "G3XA30-1", "uniprot_id": "G3XA30_MOUSE", "id": "G3XA30-1", "name": "Non-structural maintenance of chromosomes element 4", "aln": "--------MSGDSSGRRSEGRGRGRDPHRDRTRSRSRSR---SPLA---RRGAAPERREAAERPSLEDSDLSDSGDELMDPACLEAEYDQGLCRQIR----HQYRALINSVQQNREDILNAGDKLTEVLEEANTLFNEVSR--AREAVLDAQFLVLASDLGKEKAKQLRSDLS---SFDMLRYVETLLTHMGVNPLEAQEVIRD--EDRADIELIVYDSWKISGKTAENTFNKTHTFHFLLGSIHGEFPVPKPRSDRPRQPRMIEEQRAMPAQLKCMEESHQEATEKEVERILGLLQTYFREDPDTPMSFFDFVVDPHSFPRTVENIFHVSFIIRDGFARIRLDQDRLPIIEPV--------INEESEGIDHNIQIRSQGIIALSYHDWEEIVKTFEISEPVIPLSQSQQRLSA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NXX6-1", "uniprot_id": "NSE4A_HUMAN", "id": "Q9NXX6-1", "name": "Non-structural maintenance of chromosomes element 4 homolog A", "aln": "--------MSGDSSGRGPEGRGRGRDPHRDRTRSRSRSR---SPLSPRSRRGSARERREAPERPSLEDTEPSDSGDEMMDPASLEAEADQGLCRQIR----HQYRALINSVQQNREDILNAGDKLTEVLEEANTLFNEVSR--AREAVLDAHFLVLASDLGKEKAKQLRSDLS---SFDMLRYVETLLTHMGVNPLEAEELIRD--EDSPDFEFIVYDSWKITGRTAENTFNKTHTFHFLLGSIYGECPVPKPRVDRPRKVPVIQEERAMPAQLRRMEESHQEATEKEVERILGLLQTYFREDPDTPMSFFDFVVDPHSFPRTVENIFHVSFIIRDGFARIRLDQDRLPVIEPVS-------INEENEGFEHNTQVRNQGIIALSYRDWEEIVKTFEISEPVITPSQRQQKPSA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P43124-1", "uniprot_id": "NSE4_YEAST", "id": "P43124-1", "name": "Non-structural maintenance of chromosome element 4", "aln": "MSSTVISRKRRNSTVTEPDSSGETRKQKKSRSDEKSSSSKDGDPQLEFKVLQGYRDLESEMHKGRAQVTRTGDIGVAMDNLNAVDSLFNKVIGIKNNGLFAHDARAMVSISELAQISVRNLKFDDSRSMVNLENIVNSLKRYMLKEHFKLNNIAENRNDLTLAADEQSAADQQEESDGDIDRTPDDNHTDKATSSFKATSMRHSYLQQFSHYNEFSQFNWFRIGALYNTISKNAPITDHLMGPLSIEKKPRVLTQRRRNNDQVGEKITAEKITQHSLNSTQQETTPEQVKKCFKKLSKKLG--PEGSINLFKFIIDPNSFSRSIENLFYTSFLIKEGKLLMEHDEEGLPTIKIKQSISHTDSRSKEIERQRRRAAHQNHIIFQMDMPTWRKLIKKYNITSPFLD----------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VKV4-1", "uniprot_id": "Q9VKV4_DROME", "id": "Q9VKV4-1", "name": "Non-structural maintenance of chromosomes element 4", "aln": "--------------------------------------------------------------------MDSSESQSQMDDQDARILRLQN---------------LIEKNIEIEQQIENNTIGESITAIEEIIQTANDISKG-HEDRRTNSTELVLDTELLRRNFEVVGKAIQ------HNTNVTDRMVATAINDLVFKE---------------SEEDWDALCSLAIQFGRPLFTNDSMLPFIDVT---PKVVVQKQRAPRKTKSQVDEKRPEKSDQLERKDEGAASVTHMLKQIRQIYRDGNQEPIPYFKLICNPNNFMDTVQNALQLSFLVKENYISIENGEDGLPLVRVVN--------SKSVEG-----NAPSQAICSIDVTFCEKMVKHYNLHEPMLKRLPVSEK---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: : : . :: : . : : * . : : *.:.: .: .:* : . . . . : . .* . . :: : : . :. : : ::: .* : : : : .: *.:: :*:.* :::* : **::::. :. .:: ** :. .:. * .: * :. .:::* ::: .*.: ", "identical_positions": 17, "similar_positions": 90, "identity": "4.11%" }, { "cls_id": "homologset.agr.RGD:1309029", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q3KRD5-1", "uniprot_id": "TOM34_RAT", "id": "Q3KRD5-1", "name": "Mitochondrial import receptor subunit TOM34", "aln": "MAPK-VSDSVEQLRAAGN-QNFRNGQYGEASALYERALRLLQARGSADPEEESVLYSNRAACYLKDGNCTDCIKDCTSALALVPFSIKPLLRRASAYEALEKYSLAYVDYKTVLQIDNSVASALEGINRITRALMDSLGP---------------------EWRLKLPPIPVVPVSAQKRWS-------------SLPSENHKETAKSKSKETTATKNRVPSAGDVERARVLKEEGNELVKKGNHKKAIEKYSESLLFSS-LESATYSNRALCHLVLKQYKEAEKDCTEALKLDGKNVKAFYRRAQAYKALKDYKSSLADISSLLQIEPRNGPAHKLRQEVNQNMN---------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CYG7-1", "uniprot_id": "TOM34_MOUSE", "id": "Q9CYG7-1", "name": "Mitochondrial import receptor subunit TOM34", "aln": "MAPK-VSDSVEQLRAAGN-QNFRNGQYGEASALYERALRLLQARGSADPEEESVLYSNRAACYLKDGNCTDCIKDCTSALALVPFSIKPLLRRASAYEALEKYALAYVDYKTVLQIDNSVASALEGINRITRALMDSLGP---------------------EWRLKLPPIPVVPVSAQKRWN-------------SLPSDNHKETAKTKSKEATATKSRVPSAGDVERAKALKEEGNDLVKKGNHKKAIEKYSESLLCSS-LESATYSNRALCHLVLKQYKEAVKDCTEALKLDGKNVKAFYRRAQAYKALKDYKSSLSDISSLLQIEPRNGPAQKLRQEVNQNMN---------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15785-1", "uniprot_id": "TOM34_HUMAN", "id": "Q15785-1", "name": "Mitochondrial import receptor subunit TOM34", "aln": "MAPK-FPDSVEELRAAGN-ESFRNGQYAEASALYGRALRVLQAQGSSDPEEESVLYSNRAACHLKDGNCRDCIKDCTSALALVPFSIKPLLRRASAYEALEKYPMAYVDYKTVLQIDDNVTSAVEGINRMTRALMDSLGP---------------------EWRLKLPSIPLVPVSAQKRWN-------------SLPSENHKEMAKSKSKETTATKNRVPSAGDVEKARVLKEEGNELVKKGNHKKAIEKYSESLLCSN-LESATYSNRALCYLVLKQYTEAVKDCTEALKLDGKNVKAFYRRAQAHKALKDYKSSFADISNLLQIEPRNGPAQKLRQEVKQNLH---------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6ZM24-1", "uniprot_id": "Q6ZM24_DANRE", "id": "Q6ZM24-1", "name": "", "aln": "MPQKRRTQSWTDLKQAGN-ECFKAGQYGEAVTLYSQAIQQLEKSGQKKTEDLGILYSNRAASYLKDGNCNECIKDCTASLDLVPFGFKALLRRAAAFEALERYRQAYVDYKTVLQIDWNIPAAHDGVNRMTKALTEMDGP---------------------SWREKLPPIPTVPMSVKEKLG-------------QAASP----ASSSQQNNVIDDKKKAPGPDAVKKGRTLKEEGNALVKKGEHKKAMEKYTQSLAQDP-TEVTTYTNRALCYLALKMYKDAIRDCEEALRLDSANIKALYRRAQAYKELKNKKSCIEDLNSVLKIDPNNTAVQKLLQEV-QKMK---------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VBA1-1", "uniprot_id": "Q9VBA1_DROME", "id": "Q9VBA1-1", "name": "", "aln": "MEKEKKKSLLERYNIPIHYLDFAHVEKCTNAREMEKIVQILRSGEEGHYPDLQRCAEEKLKALKPDSKLFRYEEQIKQSTDLDKTELKPILDWTDAIKTKDNALNELKKVKQNLNLPSVRKLSKIDLEKESKTEKPKPAPKATSPSNTKNKEARIKSTDYRKWDKYDPDEEILRMDLNEERDQEQREKIISNHSKSVTTDKLQSERDSLYERLQAQLKNLSQLEKEQFAERHRLRGNESFKAKEYENAIEEYNCSIIYDPENAVHAYNNRAVAHLKLKKYFSAISDCQACLQIDPMNIKAHLRMAEAHNAEGKHLESLNVYKKLLDFEPDNAIAKKAVEKLTSMLGEVAPSSATRLIIEEIDPPQLKTSEPKKEAEKSEPTVVKKPEPVVSAKKPPPIKDYDLAELVKPNRMVKSNLVSAAEALGNKMQASKGGAPKKPQSPPMTPKETLLRLPQDNLNNSNKLLIQEI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : . . . : * : : :: *. . . : .:: . *.: :: . : * :*.:* : * :: :. . * *:: : .::: ::: .* .* * : :. ::. . . .: .: :. .. . : .. : .** .* ::::*:*:*. *: . :*.***:.:* ** * .* ** .*::* *:** * *:*:: . ..: ..:*.::* * .:* ::: . : ", "identical_positions": 43, "similar_positions": 106, "identity": "9.17%" }, { "cls_id": "homologset.agr.RGD:1309030", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LKM2-1", "uniprot_id": "A0ABK0LKM2_RAT", "id": "A0ABK0LKM2-1", "name": "Bromodomain and WD repeat-containing protein 1", "aln": "MAEPSPARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEAPPSISRVTSLLGAGRQSLLRTAKDCRHTVWKGSAFAALHRGRPPEMPVNYGPPPSLVDIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTLIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGPQRYMVSTGADGTVCFWQWDLE---SLKFSPRPLKFTEKPRPG-VQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQ-LEWKSILLDMAARISG-DTSAEEERFMKPKVTMIAWNQDDSTVVTAVNDHVLKVWSSYTGQLLHNLLGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGIKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFG-CSKPYEKIPDQMFFHTDYRPLIRDSNNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKFQRLVPGRENSADEHLVP-----QLGYVATSDGEVIEQVISLHTNDSGDASPESSVLDGMIRQLQQQQDLRLGVDQDV--TANGLPNEEGTPRRGSFRRLSLDIQSPPNIGLRRSGQVEGVRQMHQN--------------------------APRSQIATERDLQAWKRRVVVPEAPPGVFRRLEDIRIERGEEERNLYVIGRKKKTFQLPQ----KSNSMVLVSQSRQRTCRRKYANYSRR---------------NAGQCELSSGNESSGSVRHETSCDQSEGSCSSEDDEWRSDRRSGSDSDSPSESSSQYSDWTADTGVHLEPPLRTSCRRRVTRFCSTSEDE-----------MSTENISPPKRRRKRRKESKPKRESLRRTTPAELANMEPLYEFHPPVWITDTTLRKSPFVPQMGDEVMYFRQGHEAYIEAVRRNNIYELNPNKEPWRKMDLRDQELVKIVGLRYEVGPPTLCCLKLAFIDPATGRLTDKSFSIRYHDMPDVIDFLVLRQFYDEARQRNWQPSDRFRSIIDDAWWFGTVLSQEPYQPQYPDSHFQCYSVRWDNTEIEKLSPWDMEPIPDNVDPPEELGASISVTSDELEKLLYKPQDGEWGQRSRDEECERIISGIDQLLNLDIAAAFAGPVDLCTYPKYCTVVAYPTDLYTIRMRLVHRFYRRLSALIWEVRYIEHNARTFNEPESVIARSAKKITDQLLKFIKNQDCTNILELCNTSDSD-GDSADD--LDDSDLPKTSSGRRRVHNWKRRSRGSS--------CIESDWRRQCKALLILIFQCEDSEPFRQPVDLVEYPDYRDIIDTPMDFGTVRETLEAGNYDSPVEFCKDIRLIFSNAKAYTPNKRSKIYSMTLRLSALFEEKMKKISFDFKIGQKFKEKLRRSQRFKQRQKCNGAVPVDRSMRSVKQKQFRSQTKVIPQLMCSPSQSTSSKVPLSATRKTSAGVSSGCTSGDSSDSAGSLERVRRHRAETLRSGSVLFGSEMEDFLATSSSSSSSNSSDESKESSGAQECSLRSGVLRSSNLRVTRTRAARRKAGSVSLENGCGRKATRKRVYLSDSDNHSVETDENLKS-KAGSSRKVLRKCAAVAASKIKLMSDAED-SSSESPCSGRKLPHRNASAVARKKLLHNSDD-QSLKSET--EEVRDRNQALLMSSPHAVQNCIS-----DSESDSDLQAARKTWHANGCTSHPAAACKAKSRPIESSEEDSRCHESDHGPSSTVDPLTSGQKLGADSISEEADSEPGSS------ALGKNTHLSKKAKILSDSEDCEEKYGER---RGPEVEGSPVSEALR-EAVIVPQCLSHHGPETDVDSDGSAVREKSHSNVNDSVSRENGQRKKVSRKRFCSSDSESNLQVIQKSPIDQTSPSRITRS-AGMVTDKTKLTSDAEDVSLESVCTRSKRRRKKPVRFACTTAKSIPSSEGKHARCEVPEEQSACRSSLAEPEQQGSAENASQAANADLDFEGSSSFEQTKSIQKRQMDSVCIRAPSKTQNSSAGPSQEDPKSHTQDSDIS--LSSESVLAQKAIGENNFEEELNYGLRRWNGRRLRTYGKAPLSRTAPVTPSLQAAAEVRVKRRRVHPEVDGEDIPGQMGSSGCGPDTSPKSSDLGSVTESDVDCTDNTKAQRRKKRKGKTRVLSQESVRKDREPHTKTRPCMFNEKEAVQMHSDTLKPKTVPEKIPRRCAAIAANKIKTMCNLKEVVSGPENVGIRTNSRKLPYRQASAAAKKKLLSVYKEDDALIHSENEEE--------VYLRRFRSQKEKAQQSP--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q921C3-1", "uniprot_id": "BRWD1_MOUSE", "id": "Q921C3-1", "name": "Bromodomain and WD repeat-containing protein 1", "aln": "MAEPSPARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEVPPSISRVTSLLGAGRQSLLRTAKDCRHTVWKGSAFAALHRGRPPEMPVNYGPPPSLVEIHRGRQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTLIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGPQRYMVSTGADGTVCFWQWDLE---SLKFSPRPLKFTEKPRPG-VQMLCSSFSVGGMFLATGSTDHVIRMYFLGFDAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQ-LEWRSILLDMSARISG-DTSSEEERFMKPKVTMIAWNQDDSTVVTAVNDHVLKVWSSYTGQLLHNLLGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGIKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFG-CSKPYEKIPDQMFFHTDYRPLIRDSNNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKFQRLVPGRENSADEHLVP-----QLGYVATSDGEVIEQIISLHTNDSGDASPESSVLDGMIRQLQQQQDQRLGVDQDG--TANGLPSGEGTPRRGSFRRLSLDIQSPPNIGLRRSGQVEGVRQMHQN--------------------------APRSQIATERDLQAWKRRVVVPEAPPGMFRRLEDIRIERGEEERNLYVIGRKKKTFQVPQ----KSNSMVLVSQSRQRTCRRKYANYSRR---------------NADQCELSSGNESSGSVRHETSYDQSEGSCSSEDDEWRNDRRSGSDSDSSSDSSSQYSDWTADTGINLQPPLRMSCRRRVTRFCSTSEDE-----------MSMENISPPKRRRKRRKESKPKRESLRRMTPAELANMEHLYEFHPPVWITDTTLRKSPFVPQMGDEVMYFRQGHEAYIEAVRRNNIYELNPHKEPWRKMDLRDQELVKIVGLRYEVGPPTLCCLKLAFIDPATGRLTDKSFSIRYHDMPDVIDFLVLRQFYDEARQRNWQPCDRFRSIIDDAWWFGTVLSQEPYQPQYPDSHFQCYIVRWDNTETEKLSPWDMEPIPDNVDPPEELGASISVTSDELEKLLYKPQEGEWGQRSRDEECDRIISGIDQLLNLDIAAAFAGPVDLCTYPKYCTVVAYPTDLYTIRMRLVNRFYRRLSALIWEVRYIEHNARTFNEPESVIARSAKKITDQLLKFIKNQDCTNISELCNTSDNDEDDSADD--LDDSDLPKTSSGRRKVHNWKRRSRASG--------CIESDWRRQCKALLILIFQCEDSEPFRQPVDLDEYPDYRDIIDTPMDFGTVRETLEAGNYDSPVEFCKDIRLIFSNAKAYTPNKRSKIYSMTLRLSALFEEKMKKISFDFKIGQKFKEKLRRSQRFKQRQNCNGAVPGDRRRRNVKQKQFKSQTKVIPQLMCPPSQSTSSKVPLSATRKTSAGVSSGFTSGDSSDSAGSLERVRRQRPEVLRSGSVLFGSEMEDFLATSSSSSASNSSEESKASPGARESSLRSGVLRGSNLGVTRTRAARRKAGSVSLENGCGRKATRKRVYLSDSDNNSVETDENLKNRKCGSSRKVLRKCAAVAASKIKLMSDAED-SSSESPCSGRKLPHRNASAVARKKLLHNSDD-QSLKSET--EELKDQNQSLLISGPHSVHNSIS-----DSESDSDLRATRKTWNANGCTSHTAATCKTKSRPIESSEEDSRCHGSDHGPSSTGDPSTSGQKLRADSISEEADSEPESS------VLCKNTHLCKKAKILSDSEDCEEKCGER---RGPEVEGSPVSEALR-EAILAPQCLSHRGSETDVDSDGGAVREKSYSNENGSVSLENGQRRKVSRK--SSSDKESNLQVTQKSPKDRSSPSRITQR-ASVATDKMKLTSDAEDLSLESVCTRSKRRRKKPARFACTPAKTALSSEEKHAHCEVPEAQPACRNKLPEPEHQDSAENPSQAASADLNSGGGSSFEQRKSIQSRQMGAVCVRPPPKTQSSSAGLSQENARSQTLDSETS--LPSESVLTQKATVESNFEEELNYGLRRWNGRRLRTYGKAPLSRTAQVTPSLQASAEVGVKRRRMHPEVDGEDVPGQMGSSGCGPDTSPKASDLGSVTDSDVDCTDNTQTQRKKKRKGKARVLSKESVRKDREPHTKMRPCMLNEKDAVQMHSDTLKAKTVPEKVPRRCATVAANKIKMMCNLKEVVSGPENVGIRTISRKLPYRQASAAAKKKLLSVYKEDDAPIHSENEKE--------LYLRRFRSRKEKAQPTPR-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NSI6-1", "uniprot_id": "BRWD1_HUMAN", "id": "Q9NSI6-1", "name": "Bromodomain and WD repeat-containing protein 1", "aln": "MAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCRHTVWKGSAFAALHRGRPPEMPVNYGSPPNLVEIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGSQRYMVSTGADGTVCFWQWDLE---SLKFSPRPLKFTEKPRPG-VQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQ-LEWRSILLDMATRISG-DLSSEEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFG-CSKPYEKIPDQMFFHTDYRPLIRDSNNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKYQRLVPGRENSADEHLIP-----QLGYVATSDGEVIEQIISLQTNDNDERSPESSILDGMIRQLQQQQDQRMGADQDT--IPRGLSNGEETPRRG-FRRLSLDIQSPPNIGLRRSGQVEGVRQMHQN--------------------------APRSQIATERDLQAWKRRVVVPEVPLGIFRKLEDFRLEKGEEERNLYIIGRKRKTLQLSH----KSDSVVLVSQSRQRTCRRKYPNYGRR---------------NRSWRELSSGNESSSSVRHETSCDQSEGSGSSEEDEWRSDRKSESYSESSSDSSSRYSDWTADAGINLQPPLRTSCRRRITRFCSSSEDE-----------ISTENLSPPKRRRKRKKENKPKKENLRRMTPAELANMEHLYEFHPPVWITDTTLRKSPFVPQMGDEVIYFRQGHEAYIEAVRRNNIYELNPNKEPWRKMDLRDQELVKIVGIRYEVGPPTLCCLKLAFIDPATGKLMDKSFSIRYHDMPDVIDFLVLRQFYDEARQRNWQSCDRFRSIIDDAWWFGTVLSQEPYQPQYPDSHFQCYIVRWDNTEIEKLSPWDMEPIPDNVDPPEELGASISVTTDELEKLLYKPQAGEWGQKSRDEECDRIISGIDQLLNLDIAAAFAGPVDLCTYPKYCTVVAYPTDLYTIRMRLVNRFYRRLSALVWEVRYIEHNARTFNEPESVIARSAKKITDQLLKFIKNQHCTNISELSNTSEND-EQNAED--LDDSDLPKTSSGRRRVHDGKKSIRATN--------YVESNWKKQCKELVNLIFQCEDSEPFRQPVDLVEYPDYRDIIDTPMDFGTVRETLDAGNYDSPLEFCKDIRLIFSNAKAYTPNKRSKIYSMTLRLSALFEEKMKKISSDFKIGQKFNEKLRRSQRFKQRQNCKGDSQPNKSIRNLKPKRLKSQTKIIPELVGSPTQSTSSRTAYLGTHKTSAGISSGVTSGDSSDSAESSERRKRNRP--ITNGSTLSESEVEDSLATSLSSSASSSSEESKESSRARESSSRSGLSRSSNLRVTRTRAAQRKTGPVSLANGCGRKATRKRVYLSDSDNNSLETGEILKA-RAGNNRKVLRKCAAVAANKIKLMSDVEENSSSESVCSGRKLPHRNASAVARKKLLHNSEDEQSLKSEIEEEELKDENQLLPVSSSHTAQSNVDESENRDSESESDLRVARKNWHANGYKSHTPAPSKTKFLKIESSEEDSKSHDSDHACNRTAGPSTSVQKLKAESISEEADSEPGRSGGRKYNTFHKNASFFKKTKILSDSEDSESEEQDREDGKCHKMEMNPISGNLNCDPIAMSQCSSDHGCETDLDSDDDKIE-KPNNFMKDSASQDNGLSRKISRKRVCSSDSDSSLQVVKKSSKARTGLLRITRRCAATAANKIKLMSDVEDVSLENVHTRSKNGRKKPLHLACTTAKKKLSDCEGSVHCEVPSEQYACEGKPPDPDSEGSTKVLSQALNGDSDSEDMLNSEHK----HRHTNIHKIDAPSKRKSSSVTSSGEDSKSHIPGSETDRTFSSESTLAQKATAENNFEVELNYGLRRWNGRRLRTYGKAPFSKTKVIHDS-QETAEKEVKRKRSHPELENVKISETTGNSKFRPDTSSKSSDLGSVTESDIDCTDNTKTKRRK-TKGKAKVVRKEFVPRDREPNTKVRTCMHNQKDAVQMPSETLKAKMVPEKVPRRCATVAANKIKIMSNLKETISGPENVWIRKSSRKLPHRNASAAAKKKLLNVYKEDDTTINSESEKELEDINRKMLFLRGFRSWKENAQ-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1QKF7-1", "uniprot_id": "A0A8M1QKF7_DANRE", "id": "A0A8M1QKF7-1", "name": "", "aln": "MADTTARNGSISPLESELYYLISRYLSTGPCRKAAEALVCELEENQLLPRRLDWEGNEHPRSYEDLVTANRHIAPDHLLQICKQIGPVLDREVPSGVPGVHSLLGAGRHSLLRTSKDCCASRWKTSTFAALHRGRPPERPLNCKD-ANIVEVCRGRELTGAQRFSSINPVSNYQHMKMHRRILGHLSAVYCIAFDRTGSRIFTGSDDALVKIWSSFDGRLHSTLRGHYAEISDLAVNFENTLIAAGSCDKTIRVWCLRTCAPVAVLQGHSGSITSLQFSPFVKGSKRYMVSTGTDATVCFWQWDVN---NNEFSDRQHKFTERPRPG-VQTVCSSFSPGGMFLATGSTDDVIRIYYLGSGSPEKLAELDSHTDKVDSIQFCHSGERFVSGSRDGTARIWRLHQRHQWKSVLLDMSATLPGSAPLTDDENFFKPKVTMVSWDRHDNTVITAVNNHLLKVWNSYTGQLLHVLKGHEAEVFVLEPHPYDPRIMLSAGHDGNVFVWDLIKGTKTMHYFNMIEGQGHGAVFDCKFTPDGHRFAMTDSHGHLVIFGFG-SSKPYEKLPDQVFFHTDYRPLIRDTNGFVLDEQTQQAPHLMPPPFLVDVDGNPHPPRFQRLVPGRENIADEHLVP-----QLGYVATSDGEVVEQVISQQSAESEEVR--HSALDFAIRQLREHQDRQSGAPGEAGVPAAARVPEPGTPRRVSVNER-MEVQSPPNVGLRRSGQVEGVRQMHQN--------------------------APRSQMATERDLQAWRRRVVIPELTPSGYRAQESFRIAKGDEEVNLYNTKKRRVTHSTFRDDSDEEGPCLKRTQSRKRQKNQERKENLAE---------------EYIEFSCEEGEETASSEASEVEGSDIDSSAEDEE-EWKSD--------SSSRSSSDYSDWTADAGISVR--TSDSSRRRTTRRISSSEEEDEEDDEEEEEPADEEPAVGEEETSSPRKHKKAKSKTPKHSKPRPSINREISNEFRPPAWITDVVPRKSPFVPQMGDEVIYFRQGHEAYVDAVCRMNLYPINLDKQPWKKMQLRDQEFVKITGIKYEVCPPTLCCLKLTQIDPGTGKITDRTFSIKYHDMADVIDFLVLRQSYDEARNRVWTSNDRFRSVIDDAWWFGAIVCHEPYQSEYPDSHFQCFKVKWDNGETEKLSPWDVEAIPENAEQPESASAGVPVTDEEMMDILYKPQRGEWGDRGREQESARIIAGIEQLMTVDITAPFSGPVDLTQYPTYCTVIAYPTDLNTIKLRLKHNFYRRLSALIWDVKHIEQNAKTFNEPRSKIAQSAKIITNVLIKFISKLHCTDIMEIYNAVENMEYSDDEE--MDDIDAPGTSAGQR----LRQPSVEVV--------LDRDAWKDHCKRLLDYMFECEDSEPFRDPVDQSDYPDYTNIIDTPMDLGTVRQTLEEDRYENPIDVCKDIRLIFANAKAYTPNKRSKIYSMTLRLSAFFEENIRKIISDYKTAIKSSLKLRRSQRCRKKSQHQESVSFSQG----STRQKRATIKTQENTEQSTAKSTSAKVSGPERRRAHEAKETFRRS--SSSSSGSDQDSK----------QSLSQSDEDD--EHSSSSRAMRRETRATRKKAAQNKGAKSRRPESHVKMNGRSRSHERQKPRTSSDSDH------------EPSQGSDEASENESS-PSVSRRPRTRKTAMAAVNKMKLIDTLGDEEGTDDEGGGG-STRPATRASKRSAVIQSSSDSDDEEEAAASQEESNESGSSASEGEKSAG---------SADSDSSSHSKKNSRTAGRRPCRRPAEKKETSPLTNGHGTKRQWEESDDNSEDGGSPIESENLESDNDLVVRRKSTRRTA---------KAAVSKIKKINNTDAEEEENCTRDRRQKHRSITQESENSSDEEVETTKTLKHPHQNGRKVDAK-ELKRCKAPSERQEQSPAAKQKTTHKKSSATDACMSTTQDSEELSDDVEKSVTHRKRIASE------DEENQSDDADQRRVPKNRNRSSNARKQ---------------------------------KLCASSDESSSESDEKADRGRIKSEGTSSDEWQ----------------------KSDTSEEDKKTHPQRKPCP--TVASKGVSLRTRPKKNYIMEDS---------------------EEEFSPKMDVQAKNGVKNQQAN-----SRTRKPSGGGFKRKHGGSSESDADSKSSRSSDGNKLAEAQRKS-----AKRFKQLMGSTDSESDFETR---CKSENGRAQRSQGKLPTVSRQRRKQSESDKGSNDNGSNFESEESESEASSGSRSSPKRRLRDRDRGTARSRKPRRVVSDDDSDVSFEKPRR-----GRRIQTRNKGKRTVNYQDSE--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VC96-1", "uniprot_id": "Q9VC96_DROME", "id": "Q9VC96-1", "name": "", "aln": "--METRQPSSGDDLKPELYFLISKFLAAGPLEETAKVLIRELEEKKVLPRRLDWQGNEHEQTFEELERKYKHIGANHLLEICSRLGPLVDRELPPSVPGINSLLGTGRQNLLRTKETVYCHRSLRDYCTRLNGVSLPDS-VLTKPTHNLDRVLTGREHGGEVRRKLLVPTDLYRRTKLLRRTVGHLSSVYCVLFDRTGRYIITGADDLLIKIWSAADGRLLATLRGASSEITDIAINLDNTMLAAGSLDHILRVWDMQTTSPIAVLSAHTGMITSVNFCPSPRSDLKYLVTTSTDGSIAFWQYSTPRGQKITFAPKPTQYHEKLRPGQAQMMCTTFSPGGIFLAAGSADHHVRVYMMGEDGPKRILETEAYTDAVDSVQWSHRGLRFISGSKDGTAHIWTFES-QQWKSSKLCMTERLAS---CPEPEEGKRLKVTMVAWDASDRYVITAVNDFTIKIWDSKSAKLHRVLRGHKDELYVLESNPRDEHVLLSAGHDGQVFLWDIEQGVCVANFLNDIDGQGHGSVFDAKWSPDGTMIAATDSHGHILIFGLGVCIEKYKMLPTELFFHTDFRPLLRDAQHHVVDEQTQIMPHLMPPPFLVDADGNPHPSRFQRFVPGRESCSLDQLIPNLTVGVDGVVIDDGGAGGDAVVAAAPAEAPPAALPPAAAGGPQGANYSHIDRMIAALANRQSVNVNANDANPTNGNQSFERLTNRQMPDSNGRQSSRGNVLGSRLSTPRQGWGAAAAAPVEDQAGPSQPPAEPAAEPGQAQVQQALPLKFIRRTYVRPMKYPQLQNLKQTIYSAGQFEKQEYKREMRRRPIMINTASAASSQQPGSVGRPRNTRGNGGGARAGRRRGPQPAGGQPQPAYRTRAVRDQEPEHYDEVAPPPEEEEEDVSSNSSGDTSYSNVEENLEDSSDESETDSSDYSDWVADTPGPNLEPPKRSKRKPLSRRPRSSDDS---------------SDDERAGRSRGGQVTARKVGRKTVLFPPTDANGEIPELYRPAEWLSEVIPRKAPYYPQMGDEVVYFRQGHAKYLDAVRLKKVYKLSHSSEPWNFHTLRDHELVRVIGIKYEIRPPRLCCLKLAIID-EEGNMTGTTFKIKYHDMPDVLDFLVLRQTFDLAVQRNWSIGDRFRCMIVDGWWMGQIESRHALSADFPDSSFMCFRVRWDNGEYEFMSPWDMEPIDQ-QRVPDEVGGAVPVLPEEIRATLYQPKSEEWHRGDRDGTCRRIINGLEQVMRLSIAEHFLAPVDLNIYPDYAYLIEYPIDLTTIKSRFENHFYRRITSAQFDVRYLATNAEQYNRRHAIIVKHSRIVTDLCLRIIREPDEIDVAAVYHQLADVYHSSESENEVDSDVVPSTSTGPTTSAAAAAARQRVSSARRSTRIHSEGDWRADCRQLLDLMWARTDSAPFREPVDTIDFPDYLEIIATPMDLRTVKEDLLGGNYDDPLDFAKDVRLIFQNSKNYNTNKRSRIYAMTLRLSALFESHIKTVVTSWKAALRRANKNKSGSSGGGRGGSS----------------------------SSPNKRVKKERSTRRNQKPTAAARRLPVANSSEDEDEED-----------------DDDDDDDDDEEEASTRGRSRRRNGVAVSASSSGSNRVTSSSAAQQRRGKSSSSEEEEEEETS----------------AQATSDASSDEEERAQSNDSSPQQTRTRRARQRQRLSDDSNINDSEDSYNPNEGRGSRRRPGAARPSSNRQTNGHSSKRRRLNKS-----------------------------PANAAPGPSLPRRTRRIAGSSAEEAASHSQHDESTQDSQIGRRKGRSASSRSIGNGPSTSAAAAANSSLESPSRNTRANG-----------------TRTSSHLGAENDHSYHLPVRNGRIIESDTDSPVIRPTRQSAKRALMDWGRGSDIEEEEEEEEEDSEEAEEILPTPTKDDLPSTSRAALAQAAAGPSRQLRTNRNTVVRPAQSDDDD---DDDSDNEPLANNQQKNYQSPAKSSSTATVAPHPLS-------------------------LRRRLASPPERNTHMTRSHATSTTSSAAASRAEQQP----------------------AVSTHDHNYLGNVNSSRAPRRILSRHQRNADELDTSLDVLENSRLLSAIANHRRPTSTTNSNSASNVVTRRLRGRASQANSHDEDHEEEEAAASDEGTDGGSSSQSYEDEDEDSDSEDNQPLTSYVSPSNGRPR----RKAKTSSSSATTQERPLRRTRRPPSNNSIANDNDDDDDYVVPRSRRANRGGNQRAGRNQKRPRYNEQSEEEEAAAGYSHRSKRIRNGDAHASSQERSQASTERDQEEEEDGTSVDSEEQQVNVSSRGRVRKPSAKARGIFKE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . ::.***:**:::*::** ..:*:.*: ***: ::**:****:**** :::*:* :*:..:***:**.::**::*:* *..:. : ****:**:.**** : . : *: *: : .: : *:: * . * *:: *: ** :****:***: ***** *:**:** *:****: :*** :**** :**:*:*:* :**::**** *: :*** ::* :*:***..*:* ***::*.* :. :*:*:*.:*.::.***:. . *: : :: *: *** .* :*::** **:***:**:*. :*:* :* .*::: * :::** ***:*:.: * **:***:****:** :.. :*:* * *: :.. .: *. : ****::*: * *:****:. :*:*.* :.:* : * ** *::***.:* * :::*******.:*:**: :* :::* *:*****:***.*:: ** :* ******::***:* . : *: :* ::*****:***:**:: .*:***** ***********.******.::**:*****. : ::*:* * * ..* : ::: . : : . .: * .. : * . ... . .* *:* * * . * . . : : **. : : :. *: * : * :: . .. :.*: . . . . . . : * . .: ... ..: . : ... .** ****.**: * *: :* :*::. : . * * * * ::*. *:::. **:*: *******:****** *::** ::* :. .:**. ***:*:*:: *::**: ** ******: ** *.: . :*.*:****.**:******* :* * :* * ****.:* *.**:* : .:.. ..::*** * *: *:*** * * :****:*.* : *:. ...:.* :*: **:*: ** .*: . *** *::*:: :.*: * .**** ** *. :: ** ** **: *: :.****::: ::*::: **. :*. .: *.: :: :*: :::* : . :: : : . .. .: :*. * **:* .. *: .*: *: :: ** ***:*** ::*** :** ****: **:: * ..*:.*::..**:**** *:* *..****:**:*******:**.:::.: .:* . : * : .. : . .. : .. . . ::. . : *... . .: :* . *: . .. : . . : . :: : ..: : . .:.* . *. .::. . : ..: . * : * . .. . . . ::: .. :.. .. .* . :. : * . .* * ..: . . :. :. . . : . * . : . * * . : . . : : : . * . : . :: . .. : : :: . . *. . ..: .:* . : .: : . : . * . . *. .. . : ... . .* .* . .. * . : .. . * :.. . .: .: : .... :: . .::: : :: ..: . *: . . . : : ", "identical_positions": 509, "similar_positions": 628, "identity": "21.06%" }, { "cls_id": "homologset.agr.RGD:1309031", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q6PCN7-1", "uniprot_id": "HLTF_MOUSE", "id": "Q6PCN7-1", "name": "DNA-dependent ATPase/E3 ubiquitin-protein ligase HLTF", "aln": "-------MSYTFTRGPVWKYSQSVQYGSHENIPRLSYSTFLPHFEFQDIIPPDDFLTSDEEQDLVLFGTMRG-----QVVGLRYYTGVVNNNEMVALQREPNNPYDKNAIKVNNVNGNQVGHIKREIAAAVAYIMDNKLAQVEGVVPFGASNTFTMPLYMTFWGKEENRNVVLEQLKKHGFK-LGPTPKTLGSSLENAWGSGRAGPSYSRPAHVAVQMTTDQLKTEFDKLFEDLKEDDRTVEMEPAEAIETPLLPHQKQALAWMIARENSKELPP---FWEQRNDLYYNTITN-----FSVKERPENVHGGILADDMG-LGKTLTAIAVILTN-------------------FDDGRPLLSKRGK-KNHPGKEY--KDETIKRRGSNMDK-KEDGHS-ESSTCGEEPSISGTPEKSSCTLSQLSSVCPKRRKISVQYIESSDSEEIETSELPQKMKGKLKNVQLNTKSRVK-------------------------------------------------------------GSSKVKEDSKF--ALTFFAS--ATQRKMLKKGMSMMECSEACDTGERTR-----ATLIICPLSVLSNWIDQFGQHVKSEVHLNFYVYYGPDRIRDSAWLSKQD----IILTTYNILTHDYGTKD-----------DSPLHSIKWLRVILDEGHAIRNPNAQQTKAVLELEAERRWVLTGTPIQNSLKDLWSLLSFLKLKPFIDREWWYRIIQRPVTTGD-EGGLRRLQSLIKNITLRRTKTSKIK-GKPVLELPERKVFIQHITLSEEERKIYQSVKNEGKAAIGRYFTEGTVLAHYADVLGLLLRLRQICCHTHLLTNGMSSS-------------------------GPSRSDTPEELRKMLIEKMKIILSSG---SDEECAICLDS---LTFPVITHCAHVFCKPCICQVIHSEQPH---AKCPLCRNEIHGDNLLECPPEELAC-DSDKESSMEWKSSSKINALMHALIELRTKDPNIKSLVVSQFTTFLSLIETPLKASG----FVFTRLDGSMAQKKRVESIQRFQNTEAGSPTIMLLSLKAGGVGLNLCAASRVFLMDPAWNPAAEDQCFDRCHRLGQKQEVIITKFIVKDSVEENMLKIQNTKRDLAAGAFGTKKTDANDMKQAKINEIRTLIDL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2JVH5-1", "uniprot_id": "A0A0G2JVH5_RAT", "id": "A0A0G2JVH5-1", "name": "", "aln": "-------MSWKFKRDSVWKYSQSAQYGAHENIPRLSYPPFFPRFEFQDIIPPDDFQTSDEELDLVLFGTMRG-----QVVGIRYYTGVVNNNEMVALEREPNNPYDKNAIKVNNVNGNQVGHLKRDLAAALAYIMDNKLAQVEGVVPFGASNTFTMPLHMTFWGKEENREVVLDHLKKHGFK-LGPTPKTVGSSLENTWGSGRAGPSYSRPVHVAVQMTTEQLKTEFDKLFEDLKEDDRTIEMEPAEAVETPLLPHQKQALAWMIARENSKELPP---FWELRNDLYYNTITN-----FSVKERPENVHGGILADDMG-LGKTLTAIAVILTN-------------------FDDGRPLLGKRGK-ESHPGKEY--KDETVKLRGSNTNK-TTDGHS-EPSACSEEPSISDVSEKS--NVSDLFSFFSKRRKISVQSTESSESEEIETSKLSQKMKGKLKNTQLDTKSKVK-------------------------------------------------------------GSSKIKEDTQFALALTYFGP--ATKKKMLKKGTSVMESSKKCDTGERTR-----TTLIICPLSVLSNWIDQIGQHIKSEVDLNLYVYYGPDRIRDSTWLSKQD----IILTTYNILTHDYGTKD-----------NSPLHSIKWLRVILDEGHAIRNPNAQQTKAVLELEAERRWVLTGTPIQNSLKDLWSLLSFLKLKPFTDREWWHRIIQRPVTTGD-EGGLRRLQSLIKSITLRRTKTSKIK-GKPVLELPERKVFIQHITLSVEERKIYQSVKNEGKATIARYFTEGTVLAHYADVLGLLLRLRQICCHVHLPTNGTSSS-------------------------DPSRSDTPEELRKMLVTKMKLILSSG---SDEECSICLDS---LTFPVITHCAHVFCKPCICQVIQREQPH---AKCPLCRSNIHGHNLLECPPEELAC-DSDNKSDMEWTSSSKINALMNALIELRTKDPNIKSLVVSQFTTFLSLIETPLKASG----FVFTRLDGSMAQKKRVESIQCFQNTDAGSPTIMLLSLKAGGVGLNLCAASRVFLMDPAWNPAAEDQCFDRCHRLGQKQEVIITKFIVKDSVEENMLKIQNMKRELAAGAFGTKKTDADEMKQAKINEIRTLIDL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14527-1", "uniprot_id": "HLTF_HUMAN", "id": "Q14527-1", "name": "DNA-dependent ATPase/E3 ubiquitin-protein ligase HLTF", "aln": "-------MSWMFKRDPVWKYLQTVQYGVHGNFPRLSYPTFFPRFEFQDVIPPDDFLTSDEEVDSVLFGSLRG-----HVVGLRYYTGVVNNNEMVALQRDPNNPYDKNAIKVNNVNGNQVGHLKKELAGALAYIMDNKLAQIEGVVPFGANNAFTMPLHMTFWGKEENRKAVSDQLKKHGFK-LGPAPKTLGFNLESGWGSGRAGPSYSMPVHAAVQMTTEQLKTEFDKLFEDLKEDDKTHEMEPAEAIETPLLPHQKQALAWMVSRENSKELPP---FWEQRNDLYYNTITN-----FSEKDRPENVHGGILADDMG-LGKTLTAIAVILTN-------------------FHDGRPLPIERVK-KNLLKKEYNVNDDSMKLGGNNTSE-KADGLSKDASRCSEQPSISDIKEKSKFRMSELSSSRPKRRKTAVQYIESSDSEEIETSELPQKMKGKLKNVQSETKGRAKA------------------------------------------------------------GSSKVIEDVAFACALTSSVP--TTKKKMLKKGACAVEGSKKTDVEERPR-----TTLIICPLSVLSNWIDQFGQHIKSDVHLNFYVYYGPDRIREPALLSKQD----IVLTTYNILTHDYGTKG-----------DSPLHSIRWLRVILDEGHAIRNPNAQQTKAVLDLESERRWVLTGTPIQNSLKDLWSLLSFLKLKPFIDREWWHRTIQRPVTMGD-EGGLRRLQSLIKNITLRRTKTSKIK-GKPVLELPERKVFIQHITLSDEERKIYQSVKNEGRATIGRYFNEGTVLAHYADVLGLLLRLRQICCHTYLLTNAVSSN-------------------------GPSGNDTPEELRKKLIRKMKLILSSG---SDEECAICLDS---LTVPVITHCAHVFCKPCICQVIQNEQPH---AKCPLCRNDIHEDNLLECPPEELAR-DSEKKSDMEWTSSSKINALMHALTDLRKKNPNIKSLVVSQFTTFLSLIEIPLKASG----FVFTRLDGSMAQKKRVESIQCFQNTEAGSPTIMLLSLKAGGVGLNLSAASRVFLMDPAWNPAAEDQCFDRCHRLGQKQEVIITKFIVKDSVEENMLKIQNKKRELAAGAFGTKKPNADEMKQAKINEIRTLIDL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BAK6-1", "uniprot_id": "A0A8M2BAK6_DANRE", "id": "A0A8M2BAK6-1", "name": "", "aln": "---------MQSSSSSTASSSTPPRYAFIDFMDVG--STMTLSQELANLT--EDAGQELEAEGNVLFGSIQG-----LIVGLRYYTGAVNKGEMVSLVREPHNPYDRNAVMVANVYGSQVGHIKKELAAAMAYIMDNKLARVEGIVPYGEKNKFSMPVILTFWGKEENREVVNNLMIGFGFN-LDFR----GGSSQTSLGRDLLGLS---TKLSAIPLSAEELKNAFDKLFDDLMED-KTKEMEPAEAVCTPLLSHQKQALSWMSSRENSNDLPP---FWEENKGLYFNVLTN-----FAVKKRPEKVLGGILADDMG-LGKTLTTIALIVSN-------------------FHNGKPLPLEKCKGPSMPSAKR--KQATSKEKGVDSEE-SQESMG----------------------------LSPLKRLHDDTVRENG----------PQKKTKTTKKKSANTKKAVV-----------------------------------------------------------------LLDDVEFAAALECSSSQVVPSKKCVKKSSVPSEIS----AGSVAR-----ATLIVCPLSVLSNWLDQFEQHIRTDVTVKVYLYYGSERNRSVSLLSEQD----VVLTTYNVLSSDFGNKA-----------SSPLHNVKWLRVVLDEGHVVRNPNALQSKAVLELQSERRWILSGTPIQNSLKDLFMLLSFLKLKPFDVKEWWSRIIQRPVTMGD-RVGLKNLQALVKGITLRRTKNSKVG-GRTLVQLPERRVFVQYVTLSGMEREKYERVKGEGKNIVGRYFQEGTFMANYADVLTILMRLRQCCCHPSLVGNYTAAD-------------------------VPG---TPSELRERLIQKITLVLNSG---SDEECAICLDS---LRQPVITYCAHVFCRPCICEVIRSEKEQ---AKCPLCRAQIKTKELVEYPGEQAET-RSDTG--ENWRSSSKALALMSNLLKLRNEDPTVKSMVVSQFTGFLDVLEVALREYG----FSFTRLDGSLIQRARAKAIEDFQDSTPGSPTIMLLSLKAGGVGLNLTAASQVFVMDPAWNPAAEDQCVDRCHRLGQSRDVVITKFIVKDSVEENMVKIQKKKQELVDKAFGVK--NSQDAKQARIDDIRALMEL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P32849-1", "uniprot_id": "RAD5_YEAST", "id": "P32849-1", "name": "DNA-dependent ATPase/E3 ubiquitin-protein ligase RAD5", "aln": "MSHIEQEERKRFFNDDLDTSETSLNFKSENKESFLFANSHNDDDDDVVVSVSDTTEGEGDRSIVPVRREIEEEGQNQFITELLRIIPEMPKDLVMELNEKFGSQEEGLSLALSHYFDHNSGTSISKIPSSPNQLNTLSDTSNSTLSPSSFHPKRRRIYGFRNQTRLEDKVTWKRFIGALQVTGMATRPTVRPLKYGSQMKLKRSSEEISATKVYDSRGRKKASMASLVRIFDIQYDREIGRVSEDIAQILYPLLSSHEISFEVTLIFCDNKRLSIGDSFILQLDCFLTSLIFEERNDGESLMKRRRTEGGNKREKDNGNFGRTLTETDEELESRSKRLALLKLFDKLRLKPILDEQKALEKHKIELNSDPEIIDLDNDEICSNQVTEVHNNLRDTQHEEETMNLNQLKTFYKAAQSSESLKSLPETEPSRDVFKLELRNYQKQGLTWMLRREQEFAKAASDGEASETGANMINPLWKQFKWPNDMSWAAQNLQQDHVNVEDGIFFYANLHSGEFSLAKPILKTMIKGGILSDEMGLGKTVAAYSLVLSCPHDSDVVDKKLFDIENTAVSDNLPSTWQDNKKPYASKTTLIVVPMSLLTQWSNEFTKANN-SPDMYHEVYYGGNVSSLKTLLTKTKTPPTVVLTTYGIVQNEWTKHSKGRMTDEDVNISSGLFSVNFYRIIIDEGHNIRNRTTVTSKAVMALQGKCKWVLTGTPIINRLDDLYSLVKFLELDPWRQINYWKTFVSTPFESKNYKQAFDVVNAILEPVLLRRTKQMKDKDGKPLVELPPKEVVIKRLPFSKSQDLLYKFLLDKAEVSVKSGIARGDLLKKYSTILVHILRLRQVCCHPGLIGSQDENDEDLSKNNKLVTEQTVELDSLMRVVSERFDNSFSKEELDAMIQRLKVKYPDNKSFQSLECSICTTEPMDLDKALFTECGHSFCEKCLFEYIEFQNSKNLGLKCPNCRNQIDACRLLALVQTNSNSKNLEFKPYSPASKSSKITALLKELQLLQDSSAGEQVVIFSQFSTYLDILEKELTHTFSKDVAKIYKFDGRLSLKERTSVLADFAVKDYSRQKILLLSLKAGGVGLNLTCASHAYMMDPWWSPSMEDQAIDRLHRIGQTNSVKVMRFIIQDSIEEKMLRIQEKKRTIG----EAMDTDEDERRKRRIEEIQMLFE-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . .: . : : : . : : :. :. : : :. :: * .. . : :: : : . : * .:..: : . : . : * . : : *:: . : .. : . . . . . . : ::*: : * : ***. :: :: :.: *. * . : . : : : .* .. *. .* * :*:*** : . :.: :.* .: : . :: . : : : . : : *: .. . . . : .* . .:* .. . . . : :***: *:*:*::* ::: : . . : :*** : : *:: . ::****.:: :: .: .* *..:.: *:::**** :** .: :***: *:.: :*:*:**** * *.**: *:.**:*.*: ::* :. *. : . .: :::::: : ***** * *:.:::** :.*.:: :.:* : *: : .:.. : : .* .: :*: :* ::**** *** * . . ..* . :: ::.: .. .. **:** . * .::* *.* **. *: : *. :: : *** ** :*. .*: : : .*** **: * *: ... : ::.***: :*.::* * : ::** : : *.. : * . . .*:************* .**:.::*** *.*: ***..** **:**...* : :**::**:**:*::**: *: : . : :: :: :*::*: *:: ", "identical_positions": 172, "similar_positions": 321, "identity": "14.64%" }, { "cls_id": "homologset.agr.RGD:1309033", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AXN9-1", "uniprot_id": "RIBC2_RAT", "id": "Q6AXN9-1", "name": "RIB43A-like with coiled-coils protein 2", "aln": "-----MEVAIPKDLQQEASLAKKRYMDLCRQGQIFDARNRIIGGDTQAWDVQVRNQKIKEVTEKARDETFAAEMRHNDKVMCIMHDRELRHRKQLCRAINDFQQRFQKPETRREFDLSDPLALKKELPARVSDNDMRNTISGMQKFMGEDLNFQERKRIQKEQNREWSLQQHGEWERAQAEHKLAEHLHTQTELKFDEAARDLQRLEITTRKAVCAAVKEFNKKQVVELAERKRQVKQQEQEDNMSEITNLLHGDLLSENPQQAASNFGPRHVMLDRWKGMNREQLEEIWSTWKQQIHEKLRLQEEERQHNMDWDLRRTRKAHASLLQERQQQRLLREQRRALDCSNLSLAKQQYLQKRQLDAAPSSQPTEDYFSQFNTRSR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D4Q1-1", "uniprot_id": "RIBC2_MOUSE", "id": "Q9D4Q1-1", "name": "RIB43A-like with coiled-coils protein 2", "aln": "-----MEVAMSKDLQQEANLAKKRYIDLCRQGRIFDARNRIIGGDTQAWDFQVRDQKIKEITDKARHEAFAAEMKHNDKVMCMAHDREQRHRKQLCRAINDFQQNFQKPETRREFDLSDPLALQKELPARISDNDMRNTISGMQKFMGEDLNFQERRRFQKEQSREWFLQQHGEREKARADHLLAEHLHTQTRLKFDETARELMKLEGSTRKEVCAAVKAFNKNQVVELTERKRQEKQQEQEDNMTEITNLLHGDLLSENPRPVASSFGSHRVVLDRWKGMNREQLEEIWFTQKRQIQEKLRLQEEERQHSMDWDLRRIRKAHASLLHERQQQRLLREQRRALDCSNLNLARQQYLQKKQMNTASSSQPTEDYFSQFNTRSR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H4K1-1", "uniprot_id": "RIBC2_HUMAN", "id": "Q9H4K1-1", "name": "RIB43A-like with coiled-coils protein 2", "aln": "MGSQTMAVALPRDLRQDANLAKRRHAELCRQKRVFNARNRIIGGDTEAWDVQVHDQKIKEATEKARHETFAAEMRQNDKIMCILENRKKRDRKNLCRAINDFQQSFQKPETRREFDLSDPLALKKDLPARQSDNDVRNTISGMQKFMGEDLNFHERKKFQEEQNREWSLQQQREWKNARAEQKCAEALYTETRLQFDETAKHLQKLESTTRKAVCASVKDFNKSQAIESVERKKQEKKQEQEDNLAEITNLLRGDLLSENPQQAASSFGPHRVVPDRWKGMTQEQLEQIRLVQKQQIQEKLRLQEEKRQRDLDWDRRRIQGARATLLFERQQWRRQRDLRRALDSSNLSLAKEQHLQKKYMNEVYTNQPTGDYFTQFNTGSR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VTP5-1", "uniprot_id": "Q9VTP5_DROME", "id": "Q9VTP5-1", "name": "RIB43A-like with coiled-coils protein 2", "aln": "-MTLKIGICTKQDLDEAMKLQKREQYEDERKRRIFNAKQRLYGLDLEMLDRQILEKKKQRTAQMECDKKFEEQEQLQKRLILAQEMELEKKQRVVDSDLNYYRCRYQRKEQRREFDLNDPNFLKKARPTRVADNDISLGVSSAQIFQGEDLYNSDRKQRQREQQRAWLDQQVQERKRAEDARKQADNVLMDNVGCRDKHLQEMAKSDHQMRNQVIQRVRQFNINMAKQKQLDREREKREKYEDDMAEIYNMLSSDMLTENPDVAQSRTDPNKKIAFMYRGMTPEELRVFRLGQDQQLRLSIQRKTEAQMMDKQWEQYSINMDRTLVLHQIEDDRRRKAEFDELMRANSKLAVEQDRQRKEALVGLTNAVSDDFYDQFNKNSR", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :. :** : .* *:. : *: ::*:*::*: * * : * *: ::* :. :: .: * : : :.::: . . :.:: : :* :: :*: * ******.** *:* *:* :***: :*. * * **** :*:: *.**.* * ** * :.*. : *: : :. *: :.: : : *: * *: ** . . : :.: *::: **:::** *:* .*:*:*** . * ...: : ::**. *:*. : .:*:: .:: : * : . :*: . :: :* : :: * : * :* .** :* *:: :. : *:: ***. **", "identical_positions": 90, "similar_positions": 132, "identity": "23.56%" }, { "cls_id": "homologset.agr.RGD:1309034", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5I0E6-1", "uniprot_id": "RPAP2_RAT", "id": "Q5I0E6-1", "name": "RNA polymerase II subunit B1 CTD phosphatase Rpap2", "aln": "MADSAVPYSLGPSARASSTHR-VATGTKQTSALKRRDASKRQAELEAALQRKVESERRAVRLVEQLLEENIT-EEFLKECGMFITPAHYSDVVDERAIIKLCGYPLCQKKLGVIPKQKYRISTKTNKVYDITER---KSFCSNFCYKASKFFEAQIPKTPVWVREEERPPEFQLLKKGQSGCSGEVVQFFRDAVTAADVDAYGAFDAQCEPASSSTWSERASDERASDEEGPGFVSSLLP--------GNRPKAVGTKPQPHRQSSTVKKKAAQKMTSKHG--EQTVSEVTEQLSNCRLDS--QEKVATCKLPAKKENTQISSPGPLCDRLNTSTVSENKHSVSQVTLVGISKKSAEHFRSKFAKSNPGSGSASGLVQVRPEVAKANLLRVLKDTLTEWKTDETLKFLYGQDHGSVCLQPSAASGPDEELDEDDISC----------QAQNTLDETLPFRGSDTAIKPLPSYESLKKETEMLNLRVREFYRGRCVLNEDSTKSQDSKENELQ---RDPSFPLIDSSSQNQIRRRIVLEKLSKVLPGLLGPLQITMGDIYTELKNLVQTFRLSNRNIIHKPVEWTLIAVVLLSLLTPILGIQKHSPKNVVFTQFIATLLTELHLKCEDLENLAMIFRTSC----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VC34-1", "uniprot_id": "RPAP2_MOUSE", "id": "Q8VC34-1", "name": "Putative RNA polymerase II subunit B1 CTD phosphatase Rpap2", "aln": "MADSAVPCSLGPSTRASSTHR-DATGTKQTRALKRGDASKRQAELEAAIQRKVEFERKAVRIVEQLLEENIT-EEFLKECGMFITPAHYSDVVDERSIIKLCGYPLCQKKLGVIPKQKYRISTKTNKVYDITER---KSFCSNFCYRASKFFETQIPKTPVWVREEERPPDFQLLKKGQSGSSGEVVQFFRDAVTAADVDGSGALEAQCDPASSSSWSERASD-----EEEQGFVSSLLP--------GNRPKAVDTRPQPHTKSSIMRKKAAQNVDSKEG--EQTVSEVTEQLDNCRLDS--QEKVATCKRPLKKESTQISSPGPLCDRFNTSAISEHKHGVSQVTLVGISKKSAEHFRSKFAKSNPGSGSASGLVHVRPEVAKANLLRVLSDTLTEWKTEETLKFLYGQNHDSVCLKPSSASEPDEELDEDDISCDPGSCGPALSQAQNTLDATLPFRGSDTAIKPLPSYESLKKETEMLNLRVREFYRGRCVLNEDTTKSQDSKESVLQ---RDPSFPLIDSSSQNQIRRRIVLEKLSKVLPGLLGPLQITMGDIYTELKNLIQTFRLSNRNIIHKPVEWTLIAVVLLLLLTPILGIQKHSPKNVVFTQFIATLLTELHLKFEDLEKLTMIFRTSC----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IXW5-1", "uniprot_id": "RPAP2_HUMAN", "id": "Q8IXW5-1", "name": "Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2", "aln": "MADFAGPSSAGRKAGAPRCSR-KAAGTKQTSTLKQEDASKRKAELEAAVRKKIEFERKALHIVEQLLEENIT-EEFLMECGRFITPAHYSDVVDERSIVKLCGYPLCQKKLGIVPKQKYKISTKTNKVYDITER---KSFCSNFCYQASKFFEAQIPKTPVWVREEERHPDFQLLKEEQSGHSGEEVQLCSKAIKTSDIDNPSHFEKQYESSSSSTHSDSSSD------NEQDFVSSILP--------GNRPNSTNIRPQLHQKS-IMKKKAGHKANSKHKDKEQTVVDVTEQLGDCKLDS--QEKDATCELPLQKVNTQSSSNSTLPERLKASENSESEYSRSEITLVGISKKSAEHFKRKFAKSNQVSRSVSSSVQVCPEVGKRNLLKVLKETLIEWKTEETLRFLYGQNYASVCLKP-EASLVKEELDEDDIISDPDSHFPAWRESQNSLDESLPFRGSGTAIKPLPSYENLKKETEKLNLRIREFYRGRYVLGEETTKSQDSEE-------HDSTFPLIDSSSQNQIRKRIVLEKLSKVLPGLLVPLQITLGDIYTQLKNLVRTFRLTNRNIIHKPAEWTLIAMVLLSLLTPILGIQKHSQEGMVFTRFLDTLLEELHLKNEDLESLTIIFRTSCLPE-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8DYY5-1", "uniprot_id": "RPAP2_DROME", "id": "A8DYY5-1", "name": "Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 homolog", "aln": "--------------------------------MTTEKGEQLRQQLIAAVVKKRAAIARAHEIVVRLLEPGIP-EPEFLSLLCEIGPPNYSDIVDEREINKLCGYPLCSTVLENVPKQKYSISASKNKVYDITER---KKFCSGYCFKASEYIKSQVPTSPLWLRDRETRPSFQLLPRNT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "B0UYH6-1", "uniprot_id": "RPAP2_DANRE", "id": "B0UYH6-1", "name": "Putative RNA polymerase II subunit B1 CTD phosphatase rpap2", "aln": "-------MDAGEVTRKSRPSKSKKKGGKGTQAISAEDEAKRREAVKEQLRQKLELERKARQVVERLLEDSVT-EEFLMDCAWHITPANYKDTVEERSIAKLCGYPMCPNKLTNVPTQQYKISTKTNKVYDITER---KCFCSNFCYKASKSFELQISKIPLWLRKEESPPEIKLMKQGDGGSSGQEIKLIDKPITEADIDNP----IEDIPESNKDLIQGENG-----DIEQDFVSSVVSNQHKQVHWGKLPKRDEVSEDAAEYSHSEHEQRINGENKDESESSQTPQPQKDTTDHPALEKNASEIEGTLELLNQDKSTQQEGENTSSSQP-ESDISVPVAGDLNITQVGMSKRSAAGLKG-LLKDHHKAKTASTAISQC-------LLERLRQAFIEWRTKETMIFLYGPDYASGMQLSTAGAWEEEQLDED-------------DLDEAEVGVRSAEGGPSRTSAPVPDVETLRKETEMLELRVREFYKGVCVLPEEVETAAVKETEHTQDSGKDPPLPLVDSHAQHQIQKRIVVEKLSHSLRDIVGPLRLTMSDVINDVNNLVRTFRFTNTNIIHKSPEWTLIAVVLLSVLTEVSPLLRESLASVSSLEYISCFMKELKLEDKDLHNLVLLFKPCVPIQT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q12378-1", "uniprot_id": "RTR2_YEAST", "id": "Q12378-1", "name": "RNA polymerase II subunit B1 CTD phosphatase RTR2", "aln": "---------------------------MQIITTTFIQKVILGSHQLHEQLSIVEARMIESAIVSMLTESFCENEQTLKYLARLLSPMSYMDVINARRGKKICGYPLCYKS--------AAENSSDGFFIH-------SMYCNNYHSKCSLYLMRQLSQTPLHERRGVHLTSYINLEFDDM-YSVSLLEELVGSEVPI--------------DTVKSLIT--------------------------------------------------------------------------------------------------SFKDL---------EFDDTYKNEPLPLDVYFGQLTTDEETCIE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P40084-1", "uniprot_id": "RTR1_YEAST", "id": "P40084-1", "name": "RNA polymerase II subunit B1 CTD phosphatase RTR1", "aln": "-----------------------------MATIEDIKETALIPFQKHRQLSMHEAEVITLEIIGLLCDSECKDEKTLKYLGRFLTPDMYQDLVDERNLNKRCGYPLCGKSPERIRDPFSMNDTTKKFLLENNPYAYLSHYCSKFHFRCSQFYQVQLSDEALFARTGVHLFEDPEQDKHDIDFKVTLFEELLREKASE--------------EDIKSLIS--------------------------------------------------------------------------------------------------GLKKLGLNPDSGTTEKDDTELEDDLSKWLAQIKIVENDNPSILGDFTRED------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :: * : * : : * * * :: * * ****:* . .:. . . . :*. : :.* *:. .: * . ", "identical_positions": 16, "similar_positions": 26, "identity": "2.49%" }, { "cls_id": "homologset.agr.RGD:1309035", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "F1QTD0-1", "uniprot_id": "F1QTD0_DANRE", "id": "F1QTD0-1", "name": "", "aln": "-----------------------------------------------------------------MTSSSVPVHMQHAAGVSPHQG-------------IQLFLQGQPKVLGAVQIMIGAWTFLLG-IVTF--------AYAAGGVSYGASVIYIIAGSLSIAAEIKINSPDALCLVRASLGMNIFSAIAAGSSIIVLSQAMAFARIVTRCRDAH-CYNDV---TIFIGISGVLLVFAILEFCISISLSVFACKVACCCKPKIPVENNILIQHTPAEIPQQYIQCPQEVPEPYFQHPPAGFPPAYTEGK-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58J6J8-1", "uniprot_id": "A0AC58J6J8_DANRE", "id": "A0AC58J6J8-1", "name": "", "aln": "--MKYRKLQKCKVYLISNGILFCFIMILYRLVLYSETKMSTVGAMNPSSYVIQLQQPTQMAPVVTATSSSVPVRIQHAAGVSPLLG-------------IQAFLKGQPKALGTVQIMIGVVTFLFG-IVST--------LFAAGGVSYVASLIYITAGSLSIAAENKINSPSALCLVRASLGMNIFSAIAAGSSIIMLSLGLAFGRIISQCTDFH-CYEDT---TIVLGINGIFLLFSILEFCISISLSAFACKVACCCKPKIPEDRDPLIQHPPAEIPQQYIQYPQGIPQEYFQCPPAEAPPAYASGKLM---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1NED8-1", "uniprot_id": "A0A8M1NED8_DANRE", "id": "A0A8M1NED8-1", "name": "", "aln": "--------------------------------------MATVGAMNPSTIVIQLQPLTQTA---TVTSSSVPVRIQRVAGVSPLQG-------------IQAFLRGQPKALGTVQIMIGVLTLLFG-IASIG---YEMFFFINTGVSYWASLIYITAGSLSIAAETNIISPAGLCLVRASLGMNIFSAIAAGISIIVISVNLAFAPVFGFCGHPDYYFSER---TLLSGISGVLLVFAILEF-ISISLSVFACKATSCCKPKIPVNSNPLIQHPPAEMPPQYIQCPQEVPEPCFQHPPAESPPAYTEANKCEST", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1P8N1-1", "uniprot_id": "A0A8M1P8N1_DANRE", "id": "A0A8M1P8N1-1", "name": "", "aln": "--------------------------------------MSTVGAMNPSTIVIQLQPLTQTA---TVTSSSVPVRIQHVAGVSPLQR-------------THLFLRGQPKALGTVQIMIGVLTFLFG-ILFIG---YEPFFFINTGVSFWGSLIYIAAGSLSIAAENKINSPPALCLVRASLGMNIFSAIAAGISIIVHSMDLGFGSIYHYWAKPYYSYNHW---NIFLRISGVLLVFAILEFFISISLSVFACKVACCCKPKIPVNSSPLIQHPPAEMPPQYIQCPQEVPEPCFQHPPAEAPPAYTEGK-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2BC98-1", "uniprot_id": "A0A8M2BC98_DANRE", "id": "A0A8M2BC98-1", "name": "", "aln": "--------------------------------------MATVRTMNPSTIVIQLQPLTQTA---TGTSSSVPVRIQHVAGVSPLQG-------------IQAFLKGQPKALGTVQIMIGVLTFLLG-IVCTS---YGYYVFLFTGASYWGSLIYITAGSLSIAAENKINSPSALCLVRASLGMNIFSAIAAGIAIIVLSVNLAFGSIYHSCRDSY-CYNYR---SLFSGISCVLLLFAFLEFSISICLSAFACKVTCCYYPQIPVSSNPLIQHPPAEMPQQYIQCPQEVPEPCFQHPPAEAPPAYTEGK-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E9QHI6-1", "uniprot_id": "E9QHI6_DANRE", "id": "E9QHI6-1", "name": "", "aln": "--------------------------------------MVTVGAMNPSTIVIQLQPLTQTA---TVTSSSVPVRIQHVAGVSPLQG-------------IQAFLKGQPKALGTVQIMIGVLTILLG-IVCTN---HGYYLFFHTGAAYWGSLIYITAGSLSIAAENKMNSPAGLCLVRASLGMNIFSAIAAGISIIILSLDLAFGFTDPSCRYPYSCYGYR---TRLSGISGVLLVFAILEFFISICLSAFACKATCCFFPQISVDSSPLIQHPPAEIPQQYIQCPQEIPEPCFQHPPAESPPAYTEGE-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1P8I9-1", "uniprot_id": "A0A8M1P8I9_DANRE", "id": "A0A8M1P8I9-1", "name": "", "aln": "------------------------------------MESSKIISTEKATVVIQIN--------------PQVTQLSSDDGQEANTP-------------LQGFFKSQPKALGTVQIMIGVIVFLLG-TVLTFNVRYQPAIVVFSGITYWGSFIYISAGSLSVVAQNHLH----LCVVKASLGMNVFSTVTSGIAIILLG--IDFGLLISPSCDYSSYYGNVGICEFRQGIFGILLIFSILQFIISICISGFACKATCNSESVVNVALNQSI-------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D3ZDZ2-1", "uniprot_id": "D3ZDZ2_RAT", "id": "D3ZDZ2-1", "name": "", "aln": "MNHPTAQGAVTLSENKSSTAE-WEQEQERLIWQPGTVSMNTVTSQGPVANSVYVVAPHNSYPVVPGTMPQVPLYPSNQPQVHVIPGNLPGLVPAMTEPPAQRVLK-KGQVLGAIQILIGLVHIGLGSIMITNLFSLYTPVSLYGGFPFWGGIWFIISGSLSVAAETQPNSP---CLLNGSVGLNIFSAICSAVGIILFITDISISGGYVYPDYYP--YHD-YGVSTGVAISCVLLIFCLLELSIASVSSHFGCQVACCRYNNVDVVIPNVYATNTVVFPEPPNPIPSYSDAIRDSR------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99N10-3", "uniprot_id": "M4A8_MOUSE", "id": "Q99N10-3", "name": "Membrane-spanning 4-domains subfamily A member 8", "aln": "MNRPTAQGAVNLSGSKFSTAKSWEPEQERLTWQPGTVSMNTVTSPGPMANSVYVVAPPNSYPVVPGTVPQMPIYPSNQPQVHVISGHLPGLVPAMTEPPAQRVLK-KGQVLGAIQILIGLVHIGLGSIMITNLFSHYTPVSLYGGFPFWGGIWFIISGSLSVAAETQPNSP---CLLNGSVGLNIFSAICSAVGIMLFITDISISSGYIYPSYYP--YQENLGVRTGVAISSVLLIFCLLELSIASVSSHFGCQVACCHYNNPGVVIPNVYAANPVVIPEPPNPIPSYSEVVQDSR------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BY19-1", "uniprot_id": "M4A8_HUMAN", "id": "Q9BY19-1", "name": "Membrane-spanning 4-domains subfamily A member 8", "aln": "--------------------------------------MNSMTSAVPVANSVLVVAPHNGYPVTPGIMSHVPLYPNSQPQVHLVPGNPPSLVSNVNGQPVQKALK-EGKTLGAIQIIIGLAHIGLGSIMATVLVGEYLSISFYGGFPFWGGLWFIISGSLSVAAENQPYSY---CLLSGSLGLNIVSAICSAVGVILFITDLSIPHPYAYPDYYP--YAW--GVNPGMAISGVLLVFCLLEFGIACASSHFGCQLVCCQSSNVSVIYPNIYAANPVITPEPVTSPPSYSSEIQANK------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : :: : :.**::**:** : :* * .: ... :* :****:.*: : *:: .*:*:*:.*:: :. .::: : : : * ::*:*.:*:: *: * *.*: .. ", "identical_positions": 27, "similar_positions": 53, "identity": "8.6%" }, { "cls_id": "homologset.agr.RGD:1309036", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZKU1-1", "uniprot_id": "A0A8I5ZKU1_RAT", "id": "A0A8I5ZKU1-1", "name": "", "aln": "MEKRTREVGERVEIYGRNVEDNCNKASRGRQTENWEDRGQGLFRRDEEKAAMRHKGMGTEVRMQESRKWGAHRVPEVRGRRVSLWSQPSSSAFVPRGVKEQEARVQGKSWGVWPSERTSPHLPGPPPTRLSKMQPEVEPFSSPNPGASSSHRESGS--LDLESVEESVYRSMGRPAKSSKQYLRQVISEYEALDRELPCIRKFSEPPSAQPLCLCMETS--EDFTHLEVLQALEAELPGAMESGRVSSIRYENMNVICGTAGRRDRWLITVTDFQTRSRLLRSGLSLRGVAYPLVRHDDLLLGDYRLHLRRSLVRRRMLEALGAEPVEED", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3Z070-1", "uniprot_id": "CS081_MOUSE", "id": "D3Z070-1", "name": "Putative uncharacterized protein C19orf81 homolog", "aln": "------------------------------------------------------------------------------------------------------------------------------------MQPEVEPLISPNLGAPGSHRETGSFLVDLESMEESMSRSLGKPAKSSKQYLRQVISEYEALDRELPCIRKFSEPPSAQPLCLCMETS--EDFTHVEVLQALEAELPGAMESGRVNSIRYENMNVICGTAGRRDRWLITVTDFQTRSRLLRSGLTLRGTAYPLVRHDDLLLGDYRLHLRRSLVRRRMLEALGAEPADED", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "C9J6K1-1", "uniprot_id": "CS081_HUMAN", "id": "C9J6K1-1", "name": "Putative uncharacterized protein C19orf81", "aln": "------------------------------------------------------------------------------------------------------------------------------------MQPEVEPVCFPAMGSPTMHRKAGALLMDLETPEEMQARSLGRPIKSSKQYLRQVIAEYEALDRELPCIRKFPTPPASQPLCLCMETLPEEDFTHLEVLQALEAQLPGAMESGRVSSIRFENMNVICGTAGRRNRWLIAVTDFQTRSRLLRSGLSPRGLAHQIVRHDDLLLGDYRLHLRRSLVRRRMLEALGAEPNEEA", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *******. * *:. **::*: :***: ** **:*:* ***********:***************. **::********* *****:********:**********.***:*************:****:***************: ** *: :******************************** :* ", "identical_positions": 152, "similar_positions": 24, "identity": "46.06%" }, { "cls_id": "homologset.agr.RGD:1309037", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "B2RYA6-1", "uniprot_id": "B2RYA6_RAT", "id": "B2RYA6-1", "name": "", "aln": "MSLVAYASS-DDSEPDEPEPEPEEEDVAAPMSGPTLGGLFASLPAPKGPALLHPPPQMLAPAFPPPLLLPPPTGDPRLQPPPPLPFGLGGFPPPAGVSPAEAAGVGEGLGL--PSPQGPGLSLPP-----AVGSVGPPLGLPKPKKRTEPVRIAAPELHK-GDSDSEEDEPAKKKVVLQGSGEGTGLSALLPQPK---NLTVKETNRLLLPHAFSRKPSDVSSDAKPSRLASKTKPASLAPVLGTTTTTPSPSAIKAAAKSAALQVTKQITQEDDDSDEEVAPENFFSLPDKAEPPGVEPYPYPVPTVPEELPPGTEPEPAFQDDAANAPLEFKMAAGSSGAPWMPKPGDDYSYNQFSTYGDANAAGAYYQDYYSGGYYPAPDPALVPSQEIAPDASFIDDEAFKRLQGKRNRGREEINFVEIKGDDQLSGAQQWMTKSLTEEKTMKSFSKKKGEQPTGQQRRKHQITYLIHQAKERELELKNTWSENKLSRRQTQAKYGF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q92733-1", "uniprot_id": "PRCC_HUMAN", "id": "Q92733-1", "name": "Proline-rich protein PRCC", "aln": "MSLVAYASS-DESEPDEAEPEPEEEEAVAPTSGPALGGLFASLPAPKGPALLPPPPQMLAPAFPPPLLLPPPTGDPRLQPPPPLPFGLGGFPPPPGVSPAEAAGVGEGLGLGLPSPRGPGLNLPP-----PIGGAGPPLGLPKPKKRKEPVKIAAPELHK-GDSDSEEDEPTKKKTILQGSSEGTGLSALLPQPK---NLTVKETNRLLLPHAFSRKPSDGSPDTKPSRLASKTKTSSLAPVVGTTTTTPSPSAIKAAAKSAALQVTKQITQEEDDSDEEVAPENFFSLPEKAEPPGVEPYPYPIPTVPEELPPGTEPEPAFQDDAANAPLEFKMAAGSSGAPWMPKPGDDYSYNQFSTYGDANAAGAYYQDYYSGGYYPAQDPALVPPQEIAPDASFIDDEAFKRLQGKRNRGREEINFVEIKGDDQLSGAQQWMTKSLTEEKTMKSFSKKKGEQPTGQQRRKHQITYLIHQAKERELELKNTWSENKLSRRQTQAKYGF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W0B6-1", "uniprot_id": "Q9W0B6_DROME", "id": "Q9W0B6-1", "name": "Proline-rich protein PRCC", "aln": "MSLVAYAASSDEDSENEEENSVPQVEVIKPQAKPSTP-SEAYLARESTSGHISDEDDDYVPQEVSLQELKPPNGRLLLALPKPKVTAPAKDLENEDVDNQVTSAFAN-LPMPRTAAKGKAIVEEKDDEFLHKKALPVEIEKPPPPPVKGKVKISIPSLRDFSDVDQEKADRAKNKVDKPNVPKGSGLLSLLPQAKSERNFSKNSSSAVAYPSASTTLASSLSNNPAQPRAAPAFVPDTVKQRRAAHNTEGVDGPKAGHKKNPETKDALKSTK----SKPISKPTSLVNASDSEDDDEDGTGDFFSLNSEQKLPEVSSNE----ISALVAKRAAKMVEASS-----------KYLEEVAEKEAAEAEAARLQEEQS-------QIAQKRYHEQQLNAEAMDALVGKNAK-RRRKEAKEMQVIDISGSQVLPDREEWMRSALASSTTFQPTGVLTDEEPVAGTRRKHQITYLAHKAKANEAELQAMWSANRQTRRATQSKYGF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*******:* *:.. :* * . : :. * : *: * *. . .. : : .* . * **.* * * * . . .*. ::...: * : .:.:* .: . : * * . *:*: *.*:. .* *.*: : :*:*. . :*:** :****.* *:: :.:. : * * : .*. * :. .* *. . :: .: .* .. . *.. : : : *: *. * .:.. .:. : . : . ::** :. * .* * **. .** ::.: *:* .* *: * : * :* :*. :* . *. : :*.: :*::.::*.*.: *.. ::** .:*:...*::. . ..*:*.. ********* *:** .* **: ** *: :** **:****", "identical_positions": 113, "similar_positions": 157, "identity": "22.55%" }, { "cls_id": "homologset.agr.RGD:1309038", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "F1M9P6-1", "uniprot_id": "F1M9P6_RAT", "id": "F1M9P6-1", "name": "", "aln": "----MGGSQGSPDWRSQGPWPREDGAHMGGCFCIP---GERSLPWGPGKEGSSKDPPGLTEDISSLENK---RKCFLPQN---------------MTQDLVLSFWVRSRSRRCVNAALQEAARRRLWALENEAHEVHALFKDLSARLVSVQSQKDQFLITFKTLEEIWKFSTYLNLGYVSTCLEHLFFDHTYWLNSRLVDDTEIQVSVDDTHLENIYLGLLLQEGHFFCRAMCSVTQPADKEGEYLTLCKNELISVLSGGE-SDWEGMSLVTGQRGLVPVSALEPLPVSFHQWFLKNHPGICGLPRKKDWTGSCQIGRGRCKALMDYQQEERDELGFLQGESIDVIGFVIPGLRWFIGKSMSSGKVGFVPTRSIDLDSCSPVSKNSVFFSDEERCSLWSPGGDRKAECSGFLSALAHTDITSVYRLS-----EFESIQNLQNDLSASQPEGFREARSGGTWMERKTMGSRRS-SSSLDSS-LEDELISASSDSYHLPEPDDLDDPELFMDLSTSLEEDEMEHFAPILAFLDHEGYTDHFKSLYDFSFSFLTSSFYSFSEEDELVAYLETSRKWAKMTHRTWAHARLCFLLGRLSIRKTKLSQARVYFEEAIRVLDGAFEDLSLVAALYINLAAIYLRQRLRHKGPILLEKAGALLACLPDREFSAKNELDVVTYVLRQGIVAGSGPLEARSCFLAIRLLLNLGRHEEVLPFAERLQLLS-------GHSPASEVTATMLSSLYDKKYLPHLAVASVQKRGPQSARGMSVAIWQAYLVLQNATKILGVPFSSWCEVSALACPTLRQALAACEEQTDLNIQRTLCLLLSKMYLQHRSPDGSVQYLSQAHVLGKLLGEEEAFESSLCLAWAYLLARQTKKALEILEPLLCSLRETECVTQRGVVHNLLGLAFQDEGRTSRAAKSYLRALIRAREMGNIRNQAVSMANLGHLTLKSCMQQSARGYLLQAVRLYSEIQASKETDMELVQVLLWLGQALVSGHQLVHSRLCYEMALLFGLRHRHLNSQLQVTKSLCHFYSSVSPNPDACITYHEHWLALAQQLRDREMEGRLLESLGQLYRNLNTSRSLRRSLACIKESLRIFVDLGERDKAAEAWLGAGRLHYLMQEDELVEVYLQEAIQTALRSEELSLALKLYEEAGDVFFNGTRHRHRAVEYYRAGAVPLARRMKALRTELRIFNKLTELQISLRGYEKALEFATLAARLSVLTGDQKQELVAFHRLATVYFSLNMYEMAEDCYLKTLSLCPPWLQSPKEALYYAKVYCRLGRLTFYQLKDAHDATEYFLLALAAAV----------------------LVGDEEL----------------------------------------------------------------------------QDTIKNRLDSICQSPLWHSKPLGCSSERSRWLSGGSLAL------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80VA5-1", "uniprot_id": "S3TC2_MOUSE", "id": "Q80VA5-1", "name": "SH3 domain and tetratricopeptide repeat-containing protein 2", "aln": "---------------------------MGGCFCIP---GERSLPWGPGKEGSSKDPPGLAEDTSSLENK---RKCFLPQN---------------MTQDLVLSFCVKSRSRRCVNAALQEAARRRLWALENEAQEVHALFKDLSARLVSVQSQKDQFLITFKTLEEIWKFSTYLNLGYVSICLEHLFFDHTYWLNSRLVDDTEIQVSVDDNHLENIYLGLLLQEGHFFCRAVCSVAQPADKEGEYLTLCKNELISVLSGGE-SECEAMSLVTGQRGLVPMSALEPLPVPFHQWFLKNHPGICGLPRKRDWTGSGQIGRGRCKALMDYEQEERDELCFLQGESIDVIGFVIPGLQWFIGKSVSSGEVGFVPTRSIDLDSCSPMSKNSAFFSDEERSSLWSPGSERKAECSGFLCSLAHTDITSIYRLS-----EFEAIQNLQNDLSASQPEGFREARSGGTWMERQTIGSRRS-SGSGDSSPEEDELISASSDSYHLPEPEDLDDPELFMDLSTSLEEDDVEHFAPILAFLDHEGYTDHFKSLYDFSFSFLTSSFYSFSEEDELVAYLETSRKWAKMSHMTWAHARLCFLLGRLSIRKTKLSQARVYFEEAIRVLDGAFEDLSLVAALYINLAAIYLRQRLRHKGPTLLEKAGALLACLPDHEFSTKNELDVVTYVLRQGIVVGSGLLEARSCFLAIRLLLSLGRHEEVVPFAERLQLLS-------GHPPASEATATMLSSLYDKKYLPHLAVASVQKRGPQSARGMSLSIWQAYLVLQNATKILGVPSSNWCEVSALACPTLRQALAACEELSDQDIQRTLCLILSKMYLQHQSPDGSVHYLSQAHVLGKLLGEEEAFESSLCLAWAYLLGRQTEKALEILEPLLCSLRETECVTQRGVVHNLLGLAFEDEGRTSRAAKSYLRALIRAREMGNIRNQAVSMANLGHLTLKSCMQQSARGYLLQAVRLYSELQASKETDMELVQVLLWLGQASVSGHQLVHSRLCYEMALLFGLRHQHLSSQLQVTKSLCHFYSSVSPNPDACITYHEHWLALAQQLRDREMEGQLLESLGQLYRNLNTSRSLRRSLACIKESLRIFVDLGERDKAAEAWLGAGRLHYLMQEDELVELYLQEAIQTALRSEEPSLALKLYEEAGDVFFNGTRHRHRAVEYYRAGAVPLARRMKALRTELRIFNKLTELQISLEGYEKALEFATLAARLSVLTGDQKQELVAFHRLATVYFSLNMYEMAEDCYLKTLSLCPPWLQSPKEALYYAKVYCRLGRLTFYQLKDAHDATEYFLLALAAAV----------------------LMGDEEL----------------------------------------------------------------------------QNTIKNRLDSICQSPLWHSNPFGCSSERARWLSGGSLAL------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TF17-1", "uniprot_id": "S3TC2_HUMAN", "id": "Q8TF17-1", "name": "SH3 domain and tetratricopeptide repeat-containing protein 2", "aln": "---------------------------MGGCFCIP---RERSLTRGPGKETPSKDPTVSSECIASSEYK---EKCFLPQN---------------INPDLTLSFCVKSRSRRCVNGPLQEAARRRLWALENEDQEVRMLFKDLSARLVSIQSQRAQFLITFKTMEEIWKFSTYLNLGYVSMCLEHLLFDHKYWLNCILVEDTEIQVSVDDKHLETIYLGLLIQEGHFFCRALCSVTPPAEKEGECLTLCKNELISVKMAEAGSELEGVSLVTGQRGLVLVSALEPLPLPFHQWFLKNYPGSCGLSRKRDWTGSYQIGRGRCKALTGYEPGEKDELNFYQGESIEIIGFVIPGLQWFIGKSTSSGQVGFVPTRNIDPDSYSPMSRNSAFLSDEERCSLLALGSDKQTECSSFLHTLARTDITSVYRLS-----GFESIQNPPNDLSASQPEGFKEVRPGRAWEEHQAVGSRQS-SSSEDSS-LEEELLSATSDSYRLPEPDDLDDPELLMDLSTGQEE-EAENFAPILAFLDHEGYADHFKSLYDFSFSFLTSSFYSFSEEDEFVAYLEASRKWAKKSHMTWAHARLCFLLGRLSIRKVKLSQARVYFEEAIHILNGAFEDLSLVATLYINLAAIYLKQRLRHKGSALLEKAGALLACLPDRESSAKHELDVVAYVLRQGIVVGSSPLEARACFLAIRLLLSLGRHEEVLPFAERLQLLS-------GHPPASEAVASVLSFLYDKKYLPHLAVASVQQHGIQSAQGMSLPIWQVHLVLQNTTKLLGFPSPGWGEVSALACPMLRQALAACEELADRSTQRALCLILSKVYLEHRSPDGAIHYLSQALVLGQLLGEQESFESSLCLAWAYLLASQAKKALDVLEPLLCSLKETESLTQRGVIYNLLGLALQGEGRVNRAAKSYLRALNRAQEVGDVHNQAVAMANLGHLSLKSWAQHPARNYLLQAVRLYCELQASKETDMELVQVFLWLAQVLVSGHQLTHGLLCYEMALLFGLRHRHLKSQLQATKSLCHFYSSVSPNPEACITYHEHWLALAQQLRDREMEGRLLESLGQLYRNLNTARSLRRSLTCIKESLRIFIDLGETDKAAEAWLGAGRLHYLMQEDELVELCLQAAIQTALKSEEPLLALKLYEEAGDVFFNGTRHRHHAVEYYRAGAVPLARRLKAVRTELRIFNKLTELQISLEGYEKALEFATLAARLSTVTGDQRQELVAFHRLATVYYSLHMYEMAEDCYLKTLSLCPPWLQSPKEALYYAKVYYRLGRLTFCQLKDAHDATEYFLLALAAAV----------------------LLGDEEL----------------------------------------------------------------------------QDTIRSRLDNICQSPLWHSRPSGCSSERARWLSGGGLAL------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32T7U2-1", "uniprot_id": "A0AB32T7U2_DANRE", "id": "A0AB32T7U2-1", "name": "", "aln": "MACCCCCCCPVPCLRNCFLFSAISPAELDALWNDPPYTLAAVSELFPPNDAMTADEEAEAEAEAEVEAEGISREIYWRRKETFSGSSTVSSSGERLSPDVVLLFSGRWRSSVAPDDQLQEALRTRLRVVESNSQDVVQLFKDLSARLLSVHAEKDSFVITFKTVEEIWKFSTYLALGYVARCLENFLCDQSFWLDPALLSDVEISVTVDEDHLATLYLGLLLQEGTFFGKTLY--KSDCKEEEEELNYRRNDLVMVKDIGQEAIWEGTLLSTGKHGLVPVHDMQPLPYPFYQWFLKKYPGNAGGISVTEGLFDHPVVVGTCVAVVDHYPVVKDELHLRIGDQIKIEGFLFNTLSMFIGRHLTSGETGFVHKAHVKPESTERLNGQLVFLSEEERTALSKLNPCLEPSQADVLTNLFSTDISTVYRLDRLDDSDFTYIRNHPIPEQKTTVDQRKRTVSEKSDATPYHSSPRQSFSASRNHLDRDSEVLSFNLEDTFREMDEYEEDPPNFMDEG-IWETEEAERCDPILTLLNLEYFQDTFRTLYDLSYSFLDTFFNGLPE-DEVLQHLENLREGAKKGRMLWAHRRACFLLGRLCAKKLKYSQARVYFEEASKVPVNGFNDKPLLIALYTNLTSVYLKQKMMDKLPFTLEKASALILCLPCHNFCSVDEFELLQPIMRRAIIEKDKYLEARTCYLSVCLFLHLRKIEEALPFVERLQFLIITLSVEEGRQIAPVDLNWLLCRLYHKKYLPFLALASLSLDSGQ-DHSLNDAFQKIELFIKNSVRLNPHWKENISVLPAQVVVYLQQALAIASQGEDLKTQRDLCLSLASVYQQHGALKKAVPYAQHAAKTGNQINEEEGFEASILLAWLLVMTDEPIQAQNNLRPLLKSLNETDSPTQRGVVYNLLALCLRKQARVQEAARNFYCALQISRENGNKRNEALALANLGCLSLSIGASGLAECFLLKSFHLFQFLSES-PTDQEHVQVLLWLGRSYKDRGGSQEVRLWFEMGLLIAISANNLHSQMVVAKVLSRHYADLLLYG-QCIVYYEHCVSLCRRLKNKQLEGEYLELLSSLYLSLNTEKSSRKSLDCSKQSLRISIDLGKRQEESETWLQVGRIYYLINEDELADMYLQAAVKTALRMNDPCFAMSIYEEAGDVFFKGHRNQIAALPFYRDGSLPFARSIKDVHSEFRLLSKLTELLMKQKQYEEALQYATLAVQVSATTGVLLNERASFHRLASVYFSLGKYEMAENYYLKSLSLCPTALEHAIEVRYYVKVYCRLADLTLYRLKDAFDAMGYFHLALAAALEDKESLSTLYIIYMKLAEIHANYMPDAELSKSYMDRAQSLRNELAGYTDSKDTEETDEADADIDNKSAHSDASSGTSTLTESSMINTSLTINAQKEPEHSNGSHKDDTNTNRSDETDSGPADHTNPETSCEDNANHSNGSTLKEGLTFVI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.. : * * :: : * :* :. * : .: : :: :. *:.* * : ** . : **** * ** .:*.: ::* *********:*::::: .*:*****:********** ****: ***::: *:.:**: *:.*.**.*:**: ** .:*****:*** ** ::: ..:* * *. :*:*: * : *. * **::*** : ::*** .*:*****::** .* : . : * * *: .: :*** : *:.*.: **:: * ***: :**:.*** . :. :* . :. : .*:*:*** :* . :.. :..* * ***:::***. * *:* . : : :.. . : ..*:* *.* : :.*::* . :. : :** :** . * : *. ***::*: * : * *::***:*:*** : * .:.* **.: :** *: ** : *** * *******. :* * ********** :: ..*:* .*: :** **:::**:*:: .* . ****.**: *** :: .: .*:::: ::*:.*: . ****:*:*:: *:* * : **.:**.****:* *: *. :*. **.*****.**:**:. . * :.:. .: : *.::*:.:: . :.* . *:**** ..: * . ** *** *:.:* :* : . :: * .:* *: :.*:*.**:*: *** :: :. :* : *.*** **.**:. *****::***.*.:. :.*...**:.: ** ::* *: :*:*:::**** *:*. . *. :**::.:*: :. * ** * ***:***.: . . * :**.**:.: .:* **: .:* *.:.*:.: **.*:** ::*.::*:::::**. ** *..** .*** :* *:** * *:**** :***: :: :*:** .**::**::****.:: ** *::***: :: :*:.:*********:* *:: *: :** *::*:** :* :::*:*::.***** :. . **:**::****.::*. ** :* .:*****:**:** *****: ***:*****. *: . *. **.*** **. **: :****.** ** ******: : * ** ::* .* *. ..* *:.* ...:.:. .*. * ", "identical_positions": 480, "similar_positions": 425, "identity": "32.99%" }, { "cls_id": "homologset.agr.RGD:1309039", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "M0RA51-1", "uniprot_id": "M0RA51_RAT", "id": "M0RA51-1", "name": "", "aln": "MVRPLS--------LGELPPSYT--PP--------------ARSSAPQILAG---SLQAPLWLRAYFQGLLFSLGCRIQKHCGKVLFLGLVALGALALGLRVAVIETDLEQLWVEVGSRVSQELHYTKEKLGEEAAYTSQMLIQTARQEGANILTPEALGFHLQAALTASKVQVSLYGKSWDLNKICYKSGVPLIENG-MIERMIEKLFPCVILTPLDCFWEGAKLQG--GSAYLPGR-PDIQWTNLDPQQLLEELGPFAS-------LEGFRELLDKAQVGQAYVGRPCLDPDDPHCPPSAPNRHSRQAPNVAQELSGGCHGFSHKFMHWQEELLLGGTARDLQGQLLRAEAFQSTFLLMSPRQLYEHFRGDYQTHDIGWSEEQASMVLQAWQRRFVQLAQEALPANA----SQQIHAFSSTTLDDILQAFSEVSATRVVGGYLLMLAYACITMLRW-DCAQSQGAVGLAGVLLVALAVASGLGLCALLGITFNAATTQVLPFLALGIGVDDIFLLAHAFTKAPPNTPLPERMGECLRRTGTSVALTSINNMVAFFMAVLVPIPALRAFSLQAAIVVGCNFAAVMLVFPAVLSLDLRRRHRQRLDVLCCFSSPCSAQVIQMLPQELGDR---------------AVPVGIAHLTATVQAFTHCEASSQHVVTILPPQAHLLS-----------PTSDPLGSELYSPGGSTRDLLGQEEGTRPKASCRSLLCAHWTLAHFARYQFAPLLLQTQAKALVLLFFGALLGLSLYGATLVQDGLALTDVVPRGTKEHAFLSAQLRYFSLYEVALVTQGGFDYAHSQRALFDLHQRFSSLKAVLPPPAAQAPRTWLHYYRSWLQGIQTAFDQDWASGRITRNSYR-NGSEDGALAYKLLIQTGNAQEPLDFNQLTTRKLVDKEGLIPPELFYMGLTVWVSSDPLGLAASQANFYPPPPEWLHDKYDTTGENLRIPAAQPLEFAQFPFLLHGLQKTADFVEAIEGARAACTEAGQAGVHAYPSGSPFLFWEQYLGLRRCFLLAVCILLLCTFLVCALLLLNPWTAGLIVLVLAMMTVELFGIMGFLGIKLSAIPVVILVASVGIGVEFTVHVALGFLTSHGSRNLRAARALEQTFAPVTDGAVSTLLGLLMLAGSNFDFIIRYFFVVLTVLTLLGLLHGLLLLPVLLSILGPPPQVVQIYKESPQALSSTAPQRGGLRWG--------------------------------VSPTLPQSFARVTTSMTVA--------------------------------------LHPPPLPGAY-----------------VHPASDEPT-------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35595-1", "uniprot_id": "PTC2_MOUSE", "id": "O35595-1", "name": "Protein patched homolog 2", "aln": "MVRPLS--------LGELPPSYT--PP--------------ARSSAPHILAG---SLQAPLWLRAYFQGLLFSLGCRIQKHCGKVLFLGLVAFGALALGLRVAVIETDLEQLWVEVGSRVSQELHYTKEKLGEEAAYTSQMLIQTAHQEGGNVLTPEALDLHLQAALTASKVQVSLYGKSWDLNKICYKSGVPLIENG-MIERMIEKLFPCVILTPLDCFWEGAKLQG--GSAYLPGR-PDIQWTNLDPQQLLEELGPFAS-------LEGFRELLDKAQVGQAYVGRPCLDPDDPHCPPSAPNRHSRQAPNVAQELSGGCHGFSHKFMHWQEELLLGGTARDLQGQLLRAEALQSTFLLMSPRQLYEHFRGDYQTHDIGWSEEQASMVLQAWQRRFVQLAQEALPANA----SQQIHAFSSTTLDDILRAFSEVSTTRVVGGYLLMLAYACVTMLRW-DCAQSQGAVGLAGVLLVALAVASGLGLCALLGITFNAATTQVLPFLALGIGVDDIFLLAHAFTKAPPDTPLPERMGECLRSTGTSVALTSVNNMVAFFMAALVPIPALRAFSLQAAIVVGCNFAAVMLVFPAILSLDLRRRHRQRLDVLCCFSSPCSAQVIQMLPQELGDR---------------AVPVGIAHLTATVQAFTHCEASSQHVVTILPPQAHLLS-----------PASDPLGSELYSPGGSTRDLLSQEEGTGPQAACRPLLCAHWTLAHFARYQFAPLLLQTRAKALVLLFFGALLGLSLYGATLVQDGLALTDVVPRGTKEHAFLSAQLRYFSLYEVALVTQGGFDYAHSQRALFDLHQRFSSLKAVLPPPATQAPRTWLHYYRSWLQGIQAAFDQDWASGRITCHSYR-NGSEDGALAYKLLIQTGNAQEPLDFSQLTTRKLVDKEGLIPPELFYMGLTVWVSSDPLGLAASQANFYPPPPEWLHDKYDTTGENLRIPAAQPLEFAQFPFLLHGLQKTADFVEAIEGARAACTEAGQAGVHAYPSGSPFLFWEQYLGLRRCFLLAVCILLVCTFLVCALLLLSPWTAGLIVLVLAMMTVELFGIMGFLGIKLSAIPVVILVASIGIGVEFTVHVALGFLTSHGSRNLRAASALEQTFAPVTDGAVSTLLGLLMLAGSNFDFIIRYFFVVLTVLTLLGLLHGLLLLPVLLSILGPPPQVVQVYKESPQTLNSAAPQRGGLRWD--------------------------------RPPTLPQSFARVTTSMTVA--------------------------------------LHPPPLPGAY-----------------VHPASEEPT-------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y6C5-1", "uniprot_id": "PTC2_HUMAN", "id": "Q9Y6C5-1", "name": "Protein patched homolog 2", "aln": "MTRSPP--------LRELPPSYT--PP--------------ARTAAPQILAG---SLKAPLWLRAYFQGLLFSLGCGIQRHCGKVLFLGLLAFGALALGLRMAIIETNLEQLWVEVGSRVSQELHYTKEKLGEEAAYTSQMLIQTARQEGENILTPEALGLHLQAALTASKVQVSLYGKSWDLNKICYKSGVPLIENG-MIERMIEKLFPCVILTPLDCFWEGAKLQG--GSAYLPGR-PDIQWTNLDPEQLLEELGPFAS-------LEGFRELLDKAQVGQAYVGRPCLHPDDLHCPPSAPNHHSRQAPNVAHELSGGCHGFSHKFMHWQEELLLGGMARDPQGELLRAEALQSTFLLMSPRQLYEHFRGDYQTHDIGWSEEQASTVLQAWQRRFVQLAQEALPENA----SQQIHAFSSTTLDDILHAFSEVSAARVVGGYLLMLAYACVTMLRW-DCAQSQGSVGLAGVLLVALAVASGLGLCALLGITFNAATTQVLPFLALGIGVDDVFLLAHAFTEALPGTPLQERMGECLQRTGTSVVLTSINNMAAFLMAALVPIPALRAFSLQAAIVVGCTFVAVMLVFPAILSLDLRRRHCQRLDVLCCFSSPCSAQVIQILPQELGDG---------------TVPVGIAHLTATVQAFTHCEASSQHVVTILPPQAHLVP-----------PPSDPLGSELFSPGGSTRDLLGQEEETRQKAACKSLPCARWNLAHFARYQFAPLLLQSHAKAIVLVLFGALLGLSLYGATLVQDGLALTDVVPRGTKEHAFLSAQLRYFSLYEVALVTQGGFDYAHSQRALFDLHQRFSSLKAVLPPPATQAPRTWLHYYRNWLQGIQAAFDQDWASGRITRHSYR-NGSEDGALAYKLLIQTGDAQEPLDFSQLTTRKLVDREGLIPPELFYMGLTVWVSSDPLGLAASQANFYPPPPEWLHDKYDTTGENLRIPPAQPLEFAQFPFLLRGLQKTADFVEAIEGARAACAEAGQAGVHAYPSGSPFLFWEQYLGLRRCFLLAVCILLVCTFLVCALLLLNPWTAGLIVLVLAMMTVELFGIMGFLGIKLSAIPVVILVASVGIGVEFTVHVALGFLTTQGSRNLRAAHALEHTFAPVTDGAISTLLGLLMLAGSHFDFIVRYFFAALTVLTLLGLLHGLVLLPVLLSILGPPPEVIQMYKESPEILSPPAPQGGGLRWG--------------------------------ASSSLPQSFARVTTSMTVA--------------------------------------IHPPPLPGAY-----------------IHPAPDEPPWSPAATSSGNLSSRGPGPATG----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q98864-1", "uniprot_id": "PTC1_DANRE", "id": "Q98864-1", "name": "Protein patched homolog 1", "aln": "MASDPRDPGPAGGVFGDLPPSYTRSPPPVNSDLLRRPSYCHAAFALKQISKGKAVGQKAPLWIRARFQAFLFSLGCHIQRHCGKVLFIGLLVFGALSVGLRVAAIETDIEKLWVEAGSRVSKELRYTKEKQGEESVFTSQMLIQTPKQEGTNILTQEALLLHLEAALSASKVQVSLYGKSWDLNKICFKSGVPIIENV-MIERMIDKLFPCMIVTPLDCFWEGSKLQG--GSAYLPGM-PDIQWMNLDPLKLMEELSQFTS-------LEGFREMLDKAQVGHAYMNRPCLDPSDTDCPHSAPNKDPWQVPNIAAELQGGCHGFSKKFMHWQEELILGERVKDSQNALQSAEALQTMFLLMSPKQLYEHFKDDYEIHDINWNEDKATAILESWQRKFVEVVHGSIPQNS----SSNVYAFSTTTLNDIMKSFSDVSVIRVAGGYLLMLAYACVTMLRW-DCAKSQGAVGLAGVLLVALSVAAGLGLCSLLGLSFNAATTQVLPSLALGIGVDDMFLLGHSFTETRSNIPFKERTGDCLRRTGTSVALTSVNNMIAFFMAALVPIPALRAFSLQAAVVVVFNFAMALLIFPAILSLDLHRREDKRLDILCCFYSPCSSRVIQIQPQELSDANDNHQRAPATPTYTGSTITTSTHITTTVQAFTQCDAAGQHIVTILPPTSQISTTPPSMVLSTPTPTTDPYGSQVFTTSSSTRDLLAQVEEPKEGRECVPLPFFRWNLSSFAREKYAPLLLKPETKTVVVVVFVALLSLSLYGTTMVHDGLYLTDIVPRDTQEYEFITAQFKYFSFYNMYLVTMDGFDYARSQRQLLQLHNAFNSVKYVVKDGNHKLPRMWLHYFQDWLKGLQATFDADWEAGKITYDSYR-NGTEDGALAYKPLIQTGSKKEPFNYSQLTSRRLVDGDGLIPPEVFYIYLTVWVSNDPLGYAASQANFYPHPREWIHDKYDTTGENLRIPAAEPLEFAQFPFYLNGLRQASDFIEAIESVRTICEEFMRQGIKNYPNGYPFLFWEQYIGLRHWFLLSISVVLACTFLVCAILLLNPWTAGVIVFILPMMTVELFGIMGLIGIKLSAIPVVILIASVGIGVEFTVHIALGFLTAIGDRNTRSAVAMEHMFAPVIDGAISTLLGVLMLAGSEFDFIMRYFFAVLAILTLLGILNGLVLLPVLLSLMGPPAEVVPANNAN--HLQSPSPE------------------------------------------PMPPPMN--HHGYYAG--------------------------------------HIPKASHQAF-----------------SETSDSEY--------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P18502-1", "uniprot_id": "PTC_DROME", "id": "P18502-1", "name": "Protein patched", "aln": "MDRDSLPRVP--DTHGDVVDEKLFSDLYIR------TSWVDAQVALDQIDKGKARGSRTAIYLRSVFQSHLETLGSSVQKHAGKVLFVAILVLSTFCVGLKSAQIHSKVHQLWIQEGGRLEAELAYTQKTIGEDESATHQLLIQTTHDPNASVLHPQALLAHLEVLVKATAVKVHLYDTEWGLRDMCNMPSTPSFEGIYYIEQILRHLIPCSIITPLDCFWEGSQLLGPESAVVIPGLNQRLLWTTLNPASVMQYMKQKMSEEKISFDFETVEQYMKRAAIGSGYMEKPCLNPLNPNCPDTAPNKNSTQPPDVGAILSGGCYGYAAKHMHWPEELIVGGAKRNRSGHLRKAQALQSVVQLMTEKEMYDQWQDNYKVHHLGWTQEKAAEVLNAWQRNFSREVEQLLRKQSRIATNYDIYVFSSAALDDILAKFSHPSALSIVIGVAVTVLYAFCTLLRWRDPVRGQSSVGVAGVLLMCFSTAAGLGLSALLGIVFNAASTQVVPFLALGLGVDHIFMLTAAYAESNR----REQTKLILKKVGPSILFSACSTAGSFFAAAFIPVPALKVFCLQAAIVMCSNLAAALLVFPAMISLDLRRRTAGRADIFCCCFP-----VWKEQPK---------------------VAPPVLPLNNNNGRGARHPKSCNNNRVPLP-------------------AQNPLLEQRADIPGSSHSLAS------------------FSLATFAFQHYTPFLMRSWVKFLTVMGFLAALISSLYASTRLQDGLDIIDLVPKDSNEHKFLDAQTRLFGFYSMYAVTQGNFEYPTQQQLLRDYHDSFVRVPHVIKNDNGGLPDFWLLLFSEWLGNLQKIFDEEYRDGRLTKECWFPNASSDAILAYKLIVQTGHVDNPVDKELVLTNRLVNSDGIINQRAFYNYLSAWATNDVFAYGASQGKLYPEPRQYFHQPNE---YDLKIPKSLPLVYAQMPFYLHGLTDTSQIKTLIGHIRDLSVKYEGFGLPNYPSGIPFIFWEQYMTLRSSLAMILACVLLAALVLVSLLLLSVWAAVLVILSVLASLAQIFGAMTLLGIKLSAIPAVILILSVGMMLCFNVLISLGFMTSVGNRQRRVQLSMQMSLGPLVHGMLTSGVAVFMLSTSPFEFVIRHFCWLLLVVLCVGACNSLLVFPILLSMVGPEAELVPLEHPDRISTPSPLPVRSSKRSGKSYVVQGSRSSRGSCQKSHHHHHKDLNDPSLTTITEEPQSWKSSNSSIQMPNDWTYQPREQRPASYAAPPPAYHKAAAQQHHQHQGPPTTPPPPFPTAYPPELQSIVVQPEVTVETTHSDSNTTKVTATANIKVELAMPGRAVRSYNFTS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 355, "similar_positions": 440, "identity": "26.03%" }, { "cls_id": "homologset.agr.RGD:1309040", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LSJ3-1", "uniprot_id": "A0ABK0LSJ3_RAT", "id": "A0ABK0LSJ3-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------MLPDCLSAEDEQRCRQ-LLARTTAGLRSRPAAAAVLVPLCLVRGV--PALLYTLRSSRLVGRHKGEVSFPGGKCDPGDQDVIHTALRETQEELGLEVSKEHVWGVLQPVYDRRKATIVPVLANVGPLDLQSLRPNPEEVNGGYWGAGLTYQGIHRQASVQPLSVSCPQVDEVFELSLAHLLQTQNQGYTHFCQGGHFCYTLPVFLHGPHRVWGISAVITELTLKLLAPGIYQPSLA-------------------------VPELPRG------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CR24-1", "uniprot_id": "NUDT8_MOUSE", "id": "Q9CR24-1", "name": "Mitochondrial coenzyme A diphosphatase NUDT8", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------MLPDGLSAEDEQRCRQ-LLARTTARLRSRPAAAAVLVPLCLVRGV--PALLYTLRSSRLVGRHKGEVSFPGGKCDPDDQDVIHTALRETQEELGLEVPKEHVWGVLQPVYDREKATIVPVLANVGPLDLQSLRPNLEEV------------------------------DEVFEMSLAHLLQTQNQGYTHFCQGGHFSYTLPVFLHGPHRVWGLTAVITELTLKLLAPGFYQPSLA-------------------------VPELPRG------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WV74-1", "uniprot_id": "NUDT8_HUMAN", "id": "Q8WV74-1", "name": "Mitochondrial coenzyme A diphosphatase NUDT8", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------MLPDCLSAEGELRCRR-LLAGATARLRARPASAAVLVPLCSVRGV--PALLYTLRSSRLTGRHKGDVSFPGGKCDPADQDVVHTALRETREELGLAVPEEHVWGLLRPVYDPQKATVVPVLAGVGPLDPQSLRPNSEEV------------------------------DEVFALPLAHLLQTQNQGYTHFCRGGHFRYTLPVFLHGPHRVWGLTAVITEFALQLLAPGTYQPRLAGLTCSGAEGLARPKQPLASPCQASSTPGLNKGL-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NB50-1", "uniprot_id": "A0A8M1NB50_DANRE", "id": "A0A8M1NB50-1", "name": "", "aln": "MFSTPHVKACVNLLWVHRLSLRDAHIHLQNRHFCSRSALTPPHRCISAVSGSSEYSRTCISTRLLLARMNFSCVHSTNSVLLFAHRSLTASPSALSTIVSPEGCTGRHTHRWGLNQQSCVSISAGHVCAESRPAVFAIQRRRLHRNAQFEECVSALNEARCRRSLQANAALYERDTHRWAAVLVCLCVSRGD--PALLFTLRSAQLKGRHKGDVSFAGGKKDPSDRTVVDTALREAAEELGIHIPEEKVWGVLKPLRDKSGMMIAPVIANIGPLEALSFQPNPSEV------------------------------EEIFTLTLEHLCEPRNRGYTHFRTGERYGYTLPVFLSPKHRVWGLTAVALDQALKLIVPPEQMLERR-----------------------VIQQQQQRDAS----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VY79-1", "uniprot_id": "Q9VY79_DROME", "id": "Q9VY79-1", "name": "Nudix hydrolase domain-containing protein", "aln": "----------------------------------------------------------------------------------------------MSLIAQASRTVPQLLLHLNRHLVTSCSSAASATSSKPPDVDQSITADQLLGPESQRRCMEKMRSLPAFP--RPKALTPSRREKQTSAVLIALCQERGTNEISLLYTRRSRHLR-SHSFQISFPGGRRDDHDSSYVDCALRETEEEIGLPRHRIQVWGEAKQLQLPRTSSIVPVVGVVPDFSLSELRLNWEEV------------------------------EEAFSVPLTSLMLPKATRHTQFRSG----YSGPVFVVDHYRIWGITGYLTHLFLHCLLPPNLLPDCLKTN-------------IKFIRPFKLPPKLPHHREHSAGDPSMRT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . . . : * :***: ** ** :**:* ** :* *. ::**.**: * * :. ****: **:*: . :*** : : :.**:. : :. .:: * .** :* * :.* * .: :*:* * *: ***: :*:**::. . *: : * : ", "identical_positions": 52, "similar_positions": 54, "identity": "12.18%" }, { "cls_id": "homologset.agr.RGD:1309041", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q2TGK3-1", "uniprot_id": "ZDHC3_RAT", "id": "Q2TGK3-1", "name": "Palmitoyltransferase ZDHHC3", "aln": "MMLIPTHHFRDIERKPEYLQPEKCAPPPFPGPVGTMWFIRDGCGIACAIVTWFLVLYAEFVVLFVMLIPSRDYAYSIINGIVFNLLAFLALASHCRAMLTDPGAVPKGNATKEFIESLQLKPGQVVYKCPKCCSIKPDRAHHCSVCKRCIRKMDHHCPWVNNCVGENNQKYFVLFTMYIALISLHALIMVGFHFLHCFEEDWTKCSSFSPPTTVILLILLCFEALLFLIFTSVMFGTQVHSICTDETGIEQLKKEERRWAKKTKWMNMKAVFGHPFSLGWASPFATPDQGKADPYQYVV-------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R173-1", "uniprot_id": "ZDHC3_MOUSE", "id": "Q8R173-1", "name": "Palmitoyltransferase ZDHHC3", "aln": "MMLIPTHHFRDIERKPEYLQPEKCAPPPFPGPAGAMWFIRDGCGIACAIVTWFLVLYAEFVVLFVMLVPSRDYAYSIINGIVFNLLAFLALASHCRAMLTDPGAVPKGNATKEFIESLQLKPGQVVYKCPKCCSIKPDRAHHCSVCKRCIRKMDHHCPWVNNCVGENNQKYFVLFTMYIALISLHALIMVGFHFLHCFEEDWTKCSSFSPPTTVILLILLCFEALLFLIFTSVMFGTQVHSICTDETGIEQLKKEERRWAKKTKWMNMKAVFGHPFSLGWASPFATPDQGKADPYQYVV-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NYG2-1", "uniprot_id": "ZDHC3_HUMAN", "id": "Q9NYG2-1", "name": "Palmitoyltransferase ZDHHC3", "aln": "MMLIPTHHFRNIERKPEYLQPEKCVPPPYPGPVGTMWFIRDGCGIACAIVTWFLVLYAEFVVLFVMLIPSRDYVYSIINGIVFNLLAFLALASHCRAMLTDPGAVPKGNATKEFIESLQLKPGQVVYKCPKCCSIKPDRAHHCSVCKRCIRKMDHHCPWVNNCVGENNQKYFVLFTMYIALISLHALIMVGFHFLHCFEEDWTKCSSFSPPTTVILLILLCFEGLLFLIFTSVMFGTQVHSICTDETGIEQLKKEERRWAKKTKWMNMKAVFGHPFSLGWASPFATPDQGKADPYQYVV-------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1RE57-1", "uniprot_id": "DHC3A_DANRE", "id": "F1RE57-1", "name": "Palmitoyltransferase ZDHHC3-A", "aln": "-MRSPVPRFRDVERQASGLQPPQCLPSCHERQS-SMWFIKDACGIVCAIITWFLVFFAEFVVLFVMLIPSKNLTYSLVNGTLFNSLAFLALASHFRAMCTDPGAVPKGNATKEYIESLQLKPGQVVYKCPKCCSIKPDRAHHCSVCKRCIRKMDHHCPWVNNCVGENNQKYFVLFTMYICLISLHSLVMVVFHFLNCFEDDWTKCSTFSPPATVILLILLCFEGLLFLIFTSVMFGTQVHSICTDETGIEKLKREDPTWEKTQCWEGMKSAFGGPLSVTWFSPFTDLSCQKDDSSPVPMFPQGEIIEEDVIEIPLEPH", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *. :**::**:.. *** :* *. . :****:*.***.***:*****::**********:**:: .**::** :** ********* *** **************:*****************************************************************.*****:*:** ****:***:******:****:***********.**************************:**:*: * *. * .**:.** *:*: * ***: . * *. : ", "identical_positions": 216, "similar_positions": 46, "identity": "67.92%" }, { "cls_id": "homologset.agr.RGD:1309042", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "F1LUF8-1", "uniprot_id": "F1LUF8_RAT", "id": "F1LUF8-1", "name": "Zinc finger protein basonuclin-1", "aln": "------------------------------MRRSPSRGGRGAARAGYARREGRPRSGRRMAEAIGCTLNCSCQSFKPGKINHRQCEQCRHGWVAHALSKLRIPPVYPTSQVEIVQSNVVFDISSLMLYGTQAIPVRLKILLDRLFSVLKQDEVLQILHALDWTLQDYIRGYVLQDASGKVLDHWSIMTSEEEVATLQQFLRFGETKSIVELMAIQ------EKEEQSIVIPPATANVDIRAFIESCGHRSANLPTPVDKGNPSSMHPFENLISNMTFMLPFQFFN--------------PLPPALIGSLPEQYVLEQGQDQSRDPKQDLHGPFSDSGFLTS--TPFQVEKEQCLSCPDAVTQKEDSAHLSDSSSYSIAS---------------------------------------------------------------------KLERTQLSPEAKMKPERNSLSAKKGRVFCTACEKTFYDKGTLKIHYNAVHLKIKHKCTIEGCNMVFSSLRSRNRHSANPNPRLHMPMNRNNRDKDLRNSLNLASSETYKRPGFTVMSPDCG--PLPGYTGSVEDSKGQPAFSSIG-QNGVLFPNLKTVQPVLP------------------------------------FYRSPATPAELANTPGMLPSLPLISSSIPEQLVSTDVPFDALPKKKSRKSSMPIKIEKEAVEIADEKR--------------------------------------------------------------HSLSSDDDVPLQVVSED---------------------------------------------EPEDSSPQSDRVPEEQRTQLG-LEEPLPQ---------------GERACHLESVIEPHGAIS-----------------------RTLEQTTLT-ERESEQKVALSSVMPREVEHDGHERHFTPGLGPQIPFPDYMELQQRLLAGGLFGALSNRGMAFPFLEESK-----ELGHLSEHALVRQKEETRFQCDICKKTFKNACSMKTHEKSTHARETHACTVDGCGAAFLSRRSRDRHSSNLSLHQKVLNEEALETSEDHFRAAYLLQDVAKEAYQDVAFTPQASQTSVIFKGTSGMGSLVYP--ISQVHSASLESYNSGPPSEGTILDLSTTSSMKSESSSHSSWDSDGVSEEGTALMEDSDGNCEGQS----------LVSAEDEYPICVLMEKADQSLASLPSGLPITCHLCQKIYSNKGTFRAHYKTVHLRQLHKCKVPGCNTMFSSVRSRNRHSQNPNLHKSLASSPGHLQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35914-1", "uniprot_id": "BNC1_MOUSE", "id": "O35914-1", "name": "Zinc finger protein basonuclin-1", "aln": "-----------------------------------------------------------MAEAIGCTLNCSCQCFKPGKINHRQCEQCRHGWVAHALSKLRIPPVYPTSQVEIVQSNVVFDISSLMLYGTQAIPVRLKILLDRLFSVLKQDEVLQILHALDWTLQDYIRGYVLQDASGKVLDHWSIMTSEEEVATLQQFLRFGETKSIVELMAIQ------EKEEQSVIVPPTTANVDIRAFIESCGHRSASLPTPVDKGSPGGMHPFENLISNMTFMLPFQFFN--------------PLPPALIGSLPEQYMLEQGQDQSQEPKQELHGPFSDSSFLTS--TPFQVEKEQCLNCPETVPQKEDSAHLSDSSSYSIAS---------------------------------------------------------------------KLERTQLSPEAKVKPERNSLSAKKGRVFCTACEKTFYDKGTLKIHYNAVHLKIKHKCTIEGCNMVFSSLRSRNRHSANPNPRLHMPMNRNNRDKDLRNSLNLASSETYKRPGFTVVSPDCG--PLPGYTGSVEDSKGQPAFSSIG-QNGVLFPNLKTVQPVLP------------------------------------FYRSPATPAELANTPGMLPSLPLLSSSIPEQLVSTDMPFDALPKKKSRKSSMPIKIEKEAVEIAEEKR--------------------------------------------------------------HSLSSDDEVPLQVVSED---------------------------------------------EPEDSSPRSDRVPEEQHTQLS-LEEPLPQ---------------GERACHLESVIESHGALS-----------------------RTLEQTTLT-EREAEQKVALSSVMPREVEDGGHERHFTAGLVPQIPFPDYMELQQRLLAGGLFGALSNRGMAFPFLEESK-----ELEHLGEHALVRQKEEARFQCDICKKTFKNACSMKTHEKNTHARETHACTVEGCGAAFPSRRSRDRHSSNLSLHQKVLNEEALETSEDHFRAAYLLQDVAKEAYQDVAFTPQASQTSVIFKGTSGMGSLVYP--ISQVHSASLESYNSGPPSEGTILDLSTTSSMKSESSSHSSWDSDGVSEEGTALMEDSDGNCEGQS----------LVSGEDEYPLCVLMEKADQSLASLPSGLPITCHLCQKIYSNKGTFRAHYKTVHLRQLHKCKVPGCNTMFSSVRSRNRHSQNPNLHKSLASSPSHLQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q01954-1", "uniprot_id": "BNC1_HUMAN", "id": "Q01954-1", "name": "Zinc finger protein basonuclin-1", "aln": "-----------------------------MRRRPPSRGGRGAARARETRRQPRHRSGRRMAEAISCTLNCSCQSFKPGKINHRQCDQCKHGWVAHALSKLRIPPMYPTSQVEIVQSNVVFDISSLMLYGTQAIPVRLKILLDRLFSVLKQDEVLQILHALDWTLQDYIRGYVLQDASGKVLDHWSIMTSEEEVATLQQFLRFGETKSIVELMAIQ------EKEEQSIIIPPSTANVDIRAFIESCSHRSSSLPTPVDKGNPSSIHPFENLISNMTFMLPFQFFN--------------PLPPALIGSLPEQYMLEQGHDQSQDPKQEVHGPFPDSSFLTSSSTPFQVEKDQCLNCPDAITKKEDSTHLSDSSSYNIVT---------------------------------------------------------------------KFERTQLSPEAKVKPERNSLGTKKGRVFCTACEKTFYDKGTLKIHYNAVHLKIKHKCTIEGCNMVFSSLRSRNRHSANPNPRLHMPMNRNNRDKDLRNSLNLASSENYKCPGFTVTSPDCR--PPPSYPGSGEDSKGQPAFPNIG-QNGVLFPNLKTVQPVLP------------------------------------FYRSPATPAEVANTPGILPSLPLLSSSIPEQLISNEMPFDALPKKKSRKSSMPIKIEKEAVEIANEKR--------------------------------------------------------------HNLSSDEDMPLQVVSED---------------------------------------------EQEACSPQSHRVSEEQHVQSGGLGKPFPE---------------GERPCHRESVIESSGAIS-----------------------QTPEQATHNSERETEQTPAL-IMVPREVEDGGHEHYFTPGMEPQVPFSDYMELQQRLLAGGLFSALSNRGMAFPCLEDSK-----ELEHVGQHALARQIEENRFQCDICKKTFKNACSVKIHHKNMHVKEMHTCTVEGCNATFPSRRSRDRHSSNLNLHQKALSQEALESSEDHFRAAYLLKDVAKEAYQDVAFTQQASQTSVIFKGTSRMGSLVYP--ITQVHSASLESYNSGPLSEGTILDLSTTSSMKSESSSHSSWDSDGVSEEGTVLMEDSDGNCEGSS----------LVPGEDEYPICVLMEKADQSLASLPSGLPITCHLCQKTYSNKGTFRAHYKTVHLRQLHKCKVPGCNTMFSSVRSRNRHSQNPNLHKSLASSPSHLQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P23792-1", "uniprot_id": "DISC_DROME", "id": "P23792-1", "name": "Protein disconnected", "aln": "--------------------------------------------------------------------------------------------------------------------------------MEHIMNPFMSPAYLLGHGPHSHQHVHSHLPSHPQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PNAASPASSPGGS----SGSGSGSAAGSGTGSGSSLKP------------------------------------------------------------------RRWGSPPINLAGQFINPATGKKRVQCSICFKTFCDKGALKIHFSAVHLREMHKCTVEGCNMVFSSRRSRNRHSANPNPKLHSPHIRRKISPHDGRTAQQFPVFSPGTAAAAAAVAGRLPVAFPGLLPPPPPHHGHHPYVMFGGQAGLHGLGLLS------------------------------------------TGCQDPDSGSVDNEQDADPEDDNDFVYVDMQANSSSPAASSEDQEEHERDNEQDEEMHCSLSLASSSSIAAD----------------------------------------------------------EERAADQPLDFSLHKRR---------------------------------------------KSEQDREQEQEQEQEREREAEKEQEQDVE-------------------SDKEHEPEQEHELE-------------------------------REKRSPSDAFSMDQLLGKRKRHDSTASSSACSTAAASSASSSSASASAN--------PPQTSIKMDLDPDSDSAYMTSRRQMLPLPVLDLEEHHHLR------LLQTQMFAAAAAAAATSQAPPTAFLPAGSPVDLAKDSPPMWSLLSEMYRSMLLKTQHQQ-YNHHHQLQQQHQQEQHHHLTLSHHHQEQHH----------------------------------------------------HLGHHHMGH---------------------------------------------------------------------------HHHHHHQHHQQQPQQQSPAATNAPISV--------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VXJ5-1", "uniprot_id": "Q9VXJ5_DROME", "id": "Q9VXJ5-1", "name": "", "aln": "MNIGHEKHPPHFHPHPQPHPHPRAAAASEVHRLAAGGSVSPPPPPSTSSSLLYHLPANTNAATAATVATVSASYRHPLQGHERQQNQHHHPYQHQHHHHYHQHHPHLPTGGGNVHLSRESSPASMVMTPSRRSSPPLPPLPLTTHPIHPHSHSHSHPHPHPHPLPLALPLRHPLALNANAGGHQSPSRSSGSVQQTSSHAQSSAQSMSVHFSQLAHAQLHLQNQLQQKLSAAASRNNNNNNNNNNNNSSSTGSGTGTGNSTPTHDPNPMNPLSDLQNMQPFDFRKISSAAALGAFGGPLPLPQSPTEFGQHHHHSQQQQHQHHLHRNQFFNAMAMAYHLPPPPPPPPPDSRSPPSPPPGVGQYQHQAGSGSGSGSGSGSGSSSGAGSVDDSAGKQQRNSDKVSASGSCSSSQRMTRLALSSNMRSSRKTPHSPGGGGAGGNGGSVGGGGGKRQWGSMPANLGTQFINPVTGKKRVQCNVCLKTFCDKGALKIHFSAVHLREMHKCTVDGCSMMFSSRRSRNRHSANPNPKLHSPHLRRKISPHDGRSAQPHPLLLQAPNGLMAGLAPFG--SFPLLTPPPDLRHHAMGGSGAGSGAGVGALELKHGQDYLQRSYLDAGRFEGQRRKLAMENEHTEDEDDDEILEVGIHMAGDDDDDEADGDEDEDDDDPDGIVVVGDEIDSMPLDHENDNDNENENDESDERSTSAVSSLSQTKEQSSPGKVVQSGLEECHTYAHAHAHALTHGHAHSLGHAHALAQMAANKRKRKSQNPVRCPVQSDENSGENSIDYDVAADLSIKKVRLPAQAAASAKESEVGESTKSIPSPPLTPYGDLRPVGLCIKTEQDHEQELDQEQGQERKREQEQEPEPDPVATASKSEMKLEEQETRPADKEDDNEEDEQVSPPVVTTLDLSRAAAAIKLEPLEEINYEADENRYVRIKQELMGGDESLAEESSDKTANHNNNNNNNNNININNSVRLESDNGLEASELEEREPEPETEIEPEHEHEHEPEPETEVEVPEVPIDKENPLKCTACGEIFQNHFHLKTHHQSVHLKLHHKCNIDGCNAAFPSKRSRDRHSSNLNLHRKLLSTSDDHG-LLHAPVMPATDPLLELMSLNLNNNKSGFHHSAMVGSSAGGAGGVNPAAVGSIQAEILARICAGAHAHGLNVPLCFEALQHRFAVGHGHAGYPLIAGDGSPPSPRLFLNHGGGASPLLFAGLPRMPRFPQLTPHMLAASAGNTAAAAAAAAAAAAGMGGLSPFCRRTSSDSNSQHSITPPPKRSRSQSRSPDHCVHPAHAGDTTGITEDSGQRQSPDRIS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . :.. . . : . . * : ...:. . : * * :: : . : * ** *. * *** ***:****:.****: ****::**.*:*** ************:** * *.: . . .: : . . . . . * . : * *: * . . . . : : * . .:: .... . .::. . .. :.:: : .: : * :. : :. : : : .. * * :. * .: . : .. . . . . : : . . . :. :: ::. : . : . ... :: * * .:::. * . * . : : . : .* . : : ::. . ", "identical_positions": 62, "similar_positions": 141, "identity": "4.72%" }, { "cls_id": "homologset.agr.RGD:1309043", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VC04-1", "uniprot_id": "T106A_MOUSE", "id": "Q8VC04-1", "name": "Transmembrane protein 106A", "aln": "MGKAVSQLTS-RKDEDKPILPDNPAMASQAANYFSTGSSKPAHSCMPYEKAASSSFVTCPTCQGNGEIPQEQEKQLVALIPYGDQRLKPRRTKLFVFLSVAICLLIFSLTIFFLYPRPIAVRPVGLNSSTVTFEDAHVQLNTTNVLNIFNSNFYPITVTQLTAEVLHQASVVGQVTSSLRLHIGPLASEQMPYEVASRILDENTYKICTWPKIRVHHILLNIQGSLTCSFLSHPQQLPFESFEYVDCRENMSLPHLELPRPA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5BK83-1", "uniprot_id": "T106A_RAT", "id": "Q5BK83-1", "name": "Transmembrane protein 106A", "aln": "MGKAFSQLTS-QKDEDKSILPDNPAMASKAANYFSTGNRKPSHSCVPCEKAASTSFVTCPTCQGNGEIPQELEKQLVALIPYGDQRLKPRRTKLSVFLAVTICLLIFSLTIFFLYPRNIVVHPVGLNSSTVAFDETHVQLNMTNVLNITNSNFYPVTVTQLTAEVLHQTSVVGQVTSSLRLHIGPLASKQMPYEVASRILDENTYKICTWPKIRVHHILVNIQGALTCSYLTHPQQLPFESFEYVDCRENMSMPHLELPRPA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96A25-1", "uniprot_id": "T106A_HUMAN", "id": "Q96A25-1", "name": "Transmembrane protein 106A", "aln": "MGKTFSQLGSWREDENKSILSSKPAIGSKAVNYSSTGSSKSFCSCVPCEGTADASFVTCPTCQGSGKIPQELEKQLVALIPYGDQRLKPKHTKLFVFLAVLICLVTSSFIVFFLFPRSVIVQPAGLNSSTVAFDEADIYLNITNILNISNGNYYPIMVTQLTLEVLHLSLVVGQVSNNLLLHIGPLASEQMFYAVATKIRDENTYKICTWLEIKVHHVLLHIQGTLTCSYLSHSEQLVFQSYEYVDCRGNASVPHQLTPHPP", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:.*** * ::**:*.**..:**:.*:*.** ***. *. **:* * :*.:**********.*:**** *****************::*** ***:* ***: *: :***:** : *:*.*******:*:::.: ** **:*** *.*:**: ***** **** : *****:..* ********:** * **::* ********** :*:***:*::***:****:*:*.:** *:*:****** * *:** *:*.", "identical_positions": 165, "similar_positions": 63, "identity": "62.98%" }, { "cls_id": "homologset.agr.RGD:1309044", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P0C548-1", "uniprot_id": "PLPL2_RAT", "id": "P0C548-1", "name": "Patatin-like phospholipase domain-containing protein 2", "aln": "MFPRETKWNISFAGCGFLGVYHIGVASCLREHAPFLVANATHIYGASAGALTATALVTGACLGEAGANIIEVSKEARKRFLGPLHPSFNLVKTIRGCLLKTLPADCHTRASGRLGISLTRVSDGENVIISHFSSKDELIQANVCSTFIPVYCGLIPPTLQGVRYVDGGISDNLPLYELKNTITVSPFSGESDICPQDSSTNIHELR--ITNTSIQFNLRNLYRLSKALFPPEPMVLREMCKQGYRDGLRFLRRNGLLNQPNPLLALPPVVPQEEDAEEAAVTEERTGGED--------RILEHLPARLNEALLEACVEPKD------------------------LMTTLSNMLPVRLATAMMVPYTLPLESAVSFTIRLLEWLP---DVPEDIRWMKEQTGSICQYLVMRAKRKLGDHLPSRLSEQVELRRAQSLPSVPLSCATYSEALPNWVRNNLSLGDALAKWEECQRQLLLGLFCTNVAFPPDALRMRAPAS----------------------PTATDPATPQDPSGLPPC----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BJ56-1", "uniprot_id": "PLPL2_MOUSE", "id": "Q8BJ56-1", "name": "Patatin-like phospholipase domain-containing protein 2", "aln": "MFPRETKWNISFAGCGFLGVYHIGVASCLREHAPFLVANATHIYGASAGALTATALVTGACLGEAGANIIEVSKEARKRFLGPLHPSFNLVKTIRGCLLKTLPADCHERANGRLGISLTRVSDGENVIISHFSSKDELIQANVCSTFIPVYCGLIPPTLQGVRYVDGGISDNLPLYELKNTITVSPFSGESDICPQDSSTNIHELR--VTNTSIQFNLRNLYRLSKALFPPEPMVLREMCKQGYRDGLRFLRRNGLLNQPNPLLALPPVVPQEEDAEEAAVVEERAGEEDQLQPYRKDRILEHLPARLNEALLEACVEPKD------------------------LMTTLSNMLPVRLATAMMVPYTLPLESAVSFTIRLLEWLP---DVPEDIRWMKEQTGSICQYLVMRAKRKLGDHLPSRLSEQVELRRAQSLPSVPLSCATYSEALPNWVRNNLSLGDALAKWEECQRQLLLGLFCTNVAFPPDALRMRAPAS----------------------PTAADPATPQDPPGLPPC----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96AD5-1", "uniprot_id": "PLPL2_HUMAN", "id": "Q96AD5-1", "name": "Patatin-like phospholipase domain-containing protein 2", "aln": "MFPREKTWNISFAGCGFLGVYYVGVASCLREHAPFLVANATHIYGASAGALTATALVTGVCLGEAGAKFIEVSKEARKRFLGPLHPSFNLVKIIRSFLLKVLPADSHEHASGRLGISLTRVSDGENVIISHFNSKDELIQANVCSGFIPVYCGLIPPSLQGVRYVDGGISDNLPLYELKNTITVSPFSGESDICPQDSSTNIHELR--VTNTSIQFNLRNLYRLSKALFPPEPLVLREMCKQGYRDGLRFLQRNGLLNRPNPLLALPPARPHGPEDKDQAVESAQAEDYSQLP--GEDHILEHLPARLNEALLEACVEPTD------------------------LLTTLSNMLPVRLATAMMVPYTLPLESALSFTIRLLEWLP---DVPEDIRWMKEQTGSICQYLVMRAKRKLGRHLPSRLPEQVELRRVQSLPSVPLSCAAYREALPGWMRNNLSLGDALAKWEECQRQLLLGLFCTNVAFPPEALRMRAPADPA--------------------PAPADPASPQHQLAGPAPLLSTPAPEARPVIGALGL----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VXY8-1", "uniprot_id": "Q9VXY8_DROME", "id": "Q9VXY8-1", "name": "triacylglycerol lipase", "aln": "-MKIRTRRSLSFSGCGFLGIYHVGVAVCLRQHAPQLLLER--IAGASAGALAACCLICDLPLECMAGDFLRVVQEIQRHSLGAFSPWFNLPECLLEGMRSWLPEDAHLLASGRLHISLTRVSDRRNVVMSEFSSRQELLQALMCSCFIPGLSGLVPPQVRGVRYMDGAFSDNLPLLDEH-TVTVSPFCGESDICPRDQNPHLLQLNINWANTCIRLSRRNLRRMVRILVPGRADFMANFCQQGYDDTLQFLRRNSLLNEG--FKIQEKGMIS-WIHQQMEREKELRETPRDLEKVHTNRMTT-------NNVQHKKR-------RNR---------------------KQRTQRQTLQRTKKNQQEKIRNGRSLEMEIRNQ------EKNHQEST---NSSVEN---LTPIAEKRLENRPPEEHNHYGSSLMGSTWSLLRRVMFAPPLARHMVQVIARHLSQSLTLCDQPHFDLALMQAPAACHPSTTSCPPSTPLGDS-----------------DNDKVKAQCVCEASQIESEDQVAEVAEVEG----TSGVH----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "E1JI03-1", "uniprot_id": "E1JI03_DROME", "id": "E1JI03-1", "name": "triacylglycerol lipase", "aln": "-------MNLSFAGCGFLGIYHVGVAVCFKKYAPHLLLEK--IGGASAGSLAACCLLCDLPLGSMTSDFFRVVNEARRYSLGPFSPSFNIQTCLLEGLQKHLPDDAHKRVNGRLHISLTRVYDGKNVIISEFESREEVLQALLCACFIPGFSGILPPRFRGVRYMDGAFSDNLPILDEN-TITVSPFCGESDICPRDQSSQLFHL--NWANTSIEISRQNINRFVRILFPPRPEFLSKFCQQGFDDALQFLHRNNLINCRRCVAVQSTFVVSETVAQPQEFDPECRECKKHRKDALSSNMPQTVLDVIQDYIEQANKGLANWIFKHRGIKLLSLPATVPMDFLLATISKISALTPKLTKQARVMVEDLILQLNHAMRIRLLNKFTLYDQPHFDATGLLHSSRLYGPRVSILVDECGATPLEDDVDNFEHVLKMTTHNDALYAYYYTDSNTNKVKVTEIFDFDEITEHDKLATDLQIYEGSVEDHPNPHQHSHNTVVSEWNGVESDFFIDAHTPNVEDSKTSAPQFSRLDLETESDASVLSDPEVDQTFSSTASTHSSDMYIEIEG", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:**:******:*::*** *::::** *: : * *****:*:* .*: . * ..::.* :* :: **.: * **: : : . ** *.* ..*** ****** * .**::*.*.*::*::** :*: *** .*::** .:****:**.:*****: : : *:*****.*******:*...:: .* :**.*.:. :*: *: : *.* .. .: ::*:**: * *:**:**.*:* . : .: : : . . : : ** . : ..: : ... . . : : :: :: :* : . . : . .: ", "identical_positions": 109, "similar_positions": 122, "identity": "19.29%" }, { "cls_id": "homologset.agr.RGD:1309045", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZI34-1", "uniprot_id": "D3ZI34_RAT", "id": "D3ZI34-1", "name": "", "aln": "------MTLKYLWLVALVALYISPIQSQNC----VYLDHTILENMKLLSSIRTTFPLRCLKDITDFEFPQEILLYVQHVKKDIKAVTYHISSLALIIFSLKDSISLATEERLERIRSGLFKQVQQARECMVDEENKNTEEDSTSQ---HPHSEGFKAVY-LELNKYFFRIRKFLVNKKYSFCAWKIVVVEIRRCFSIFYK---LLNMN-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TSL0-1", "uniprot_id": "IFNK_MOUSE", "id": "Q7TSL0-1", "name": "Interferon kappa", "aln": "------MTPKFLWLVALVALYIPPIQSLNC----VYLDDSILENVKLLGSTMTGFPLRCLKDITDFKFPKEILPYIQHMKREINAVSYRISSLALTIFNLKGSIPPVTEEHWERIRSGLFKQVRQAQECFMDEEKENRE---------HPHSEDFLTVY-LELGKYFFRIKKFLINKKYSFCAWKIVTVEIRRCFIIFSKSRKLLKMISESPTFKQELK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P0W0-1", "uniprot_id": "IFNK_HUMAN", "id": "Q9P0W0-1", "name": "Interferon kappa", "aln": "MSTKPDMIQKCLWLEILMGIFIAGTLSLDCNLLNVHLRRVTWQNLRHLSSMSNSFPVECLRENIAFELPQEFLQYTQPMKRDIKKAFYEMSLQAFNIFS-QHTFKYWKERHLKQIQIGLDQQAEYLNQCLEEDKNENEDMKEMKENEMKPSEARVPQLSSLELRRYFHRIDNFLKEKKYSDCAWEIVRVEIRRCLYYFYKFTALFRRK-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8E6E3-1", "uniprot_id": "A8E6E3_DANRE", "id": "A8E6E3-1", "name": "", "aln": "-----MDLHRVAWLCTFFCFVQVWSLPTNCN----LQKNLMKRTYTLLETAGGLFPMQCLDDRVSIPFPQNVFEYNEDQVTGVEKAVYQTLQNIDALFENFGDPDQWDAEKLDDFRGIVYRQIKYS-TCIMNKTEVAQD---------FPSRE-------ASLKVYFETISSTLKEKNSSYCAWEIVRSEILRTLEFILKNNSDIML------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ** :. : . :* .. * : **:.** : : :*::.: * : :: . *. :*. .: . :: : :* . *: :. : : * .* ** * . * :*: * ***:** ** * : : * : ", "identical_positions": 31, "similar_positions": 46, "identity": "14.16%" }, { "cls_id": "homologset.agr.RGD:1309046", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GLM3-1", "uniprot_id": "A0A8I6GLM3_RAT", "id": "A0A8I6GLM3-1", "name": "Nuclear receptor coactivator", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSGLGDSSSDPANPDSHKRKGSPCDTLAS-------STEKRRREQENKYLEELAELLSANISDIDSLSVKPDKCKILKKTVDQIQLMKRMEQEKS---TTDDD-----------------------------------------VQKSDISSSSQGVIEKESLG-------------PLLLEALDGFFFVVNCEGRIVFVSENVTSYLGYNQEELMNTSVYSILHVGDHAEFVKNLLPKSLVN------------------------------------------------GVPWPQEATRRNSHTFNCRMLIHPP-----DEPGTENQEACQRYEVMQCFTVSQPKSIQEDGEDFQSCLICIARRLPRPPAITG-VESFMTKQ---------DTTGKIISIDTSSLRAAGRTGWEDLVRKCIYAFFQPQGREPSYARQLFQEVMTRGTASSP-----------SYRFILNDG-TMLSAHTKCKLCYPQSPDMQPFIMGIHIIDREHSGLSPQDDTNSG-------MSIPRINPSVNPGISPAHGVTRSSTLPPSNNNMVSARANRQQSTDLN-SGSSHSNSSSSQGSFGCSPGNQIVASVALSQGQAGSQSSNPSLNLNNSPMEGTGISLAQFMSPRR-QANSGLATRARMSNNSFPPNIPTLSSPVGITSGACSNNNRSYSNIPVTSLQGMNEGPNNSVGFSAGSPVLRQMSSQNSPSRLSMQPAKAESKDNKE--------IASILNEMIQSDNS---ANEGKPLDSGLLHNNDRLSDGDSKYSQTSHKLVQLLTTTAEQQLRHADIDTSCKDVLSCTGTSSSASSNPSGGTCPSSHSSLTERHKILHRLLQEGSPSDITTLSVEPEKKDSASASTAMSVSGQAQGSASIKLELDASKKKESKD-------------HQLLRYLLDKD--EKDLRSTP---NLSLDDVKVKVEKKEQMD--PCNTNPAPVTKPAPEEVKLESQSQFS--ADLDQFDQLLPTLEKAAQLPGLCETDRMDGAVPGVNIKSEILPASLQPTP---------------------ARSAPRLNRLPELELEAIDNQFGQPGAGDQIPWANNTVTAINQ--------------------------------SKPEDQCISSQLDELLCPPTTVEGRNDEKALLEQLVSFLSGKDETELAELDRALGIDKLVQGGGLDVLSER-------------------FPPQQATPPLMMEDRPTLYPQPY-SSPSPTAGLSGPFQGMVR------------------------------QKPSLGTMPVQVTPPRGTFSPNMGMQPRQTLNRPPAAPNQLRLQLQQRLQGQQQLMHQNRQAILN-------------------------------------------QFAANAPVGMNMRSGMQQ-QITPQ------PPLN---AQMLAQRQRELYSQQHR----QRQIIQQQRAMLMRHQSFGNNIPPSSGLP--VQMGNPRLPQGAPQQFPYPPNYGTNPGTPPASTSPFSQLAAN----------------PEASLATRSSMVNRGMAG---------------NMGGQFGTGISPQ---------------MQQNVFQYPG-SGLVPQAEANFAPSLSPGSSMVPMPIPP-QSSLLQQTPPTSGYQSPDMKAWQQGTMGNNNVFSQAVQ-SQPAPAQPGVYNNMSITVSMAGGNANVQNMNPMMGQMQMSSLQMPGMNTVCSEQMNDPALRHTGLYCNQLSSTDLLKTEADGNQQVQQLQVFADVQCTVNLVGGDP------------------------YLNQPGPLGTQKPTSGPQTPQAQQKSLLQQLLTE--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70365-1", "uniprot_id": "NCOA1_MOUSE", "id": "P70365-1", "name": "Nuclear receptor coactivator 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSGLGDSSSDPANPDSHKRKGSPCDTLAS-------STEKRRREQENKYLEELAELLSANISDIDSLSVKPDKCKILKKTVDQIQLMKRMEQEKS---TTDDD-----------------------------------------VQKSDISSSSQGVIEKESLG-------------PLLLEALDGFFFVVNCEGRIVFVSENVTSYLGYNQEELMNTSVYSILHVGDHAEFVKNLLPKSLVN------------------------------------------------GVPWPQEATRRNSHTFNCRMLIHPP-----EDPGTENQEACQRYEVMQCFTVSQPKSIQEDGEDFQSCLICIARRLPRPPAITG-VESFMTKQ---------DTTGKIISIDTSSLRAAGRTGWEDLVRKCIYAFFQPQGREPSYARQLFQEVMTRGTASSP-----------SYRFILNDG-TMLSAHTKCKLCYPQSPDMQPFIMGIHIIDREHSGLSPQDDSNSG-------MSIPRINPSVNPGISPAHGVTRSSTLPPSNNNMVSARVNRQQSSDLN-SSSSHTNSSNNQGNFGCSPGNQIVANVALNQGQAGSQSSNPSLNLNNSPMEGTGIALSQFMSPRR-QANSGLATRARMSNNSFPPNIPTLSSPVGITSGACNNNNRSYSNIPVTSLQGMNEGPNNSVGFSAGSPVLRQMSSQNSPSRLSMQPAKAESKDSKE--------IASILNEMIQSDNSDNSANEGKPLDSGLLHNNDRLSEGDSKYSQTSHKLVQLLTTTAEQQLRHADIDTSCKDVLSCTGTSSSASSNPSGGTCPSSHSSLTERHKILHRLLQEGSPSDITTLSVEPEKKDSVPASTAVSVSGQSQGSASIKLELDAAKKKESKD-------------HQLLRYLLDKD--EKDLRSTP---NLCLDDVKVKVEKKEQMD--PCNTNPTPMTKPAPEEVKLESQSQFT--ADLDQFDQLLPTLEKAAQLPSLCETDRMDGAVTGVSIKAEVLPASLQPTT---------------------ARAAPRLSRLPELELEAIDNQFGQPGAGDQIPWANNTLTTINQ--------------------------------NKPEDQCISSQLDELLCPPTTVEGRNDEKALLEQLVSFLSGKDETELAELDRALGIDKLVQGGGLDVLSER-------------------FPPQQATPPLMMEDRPTLYSQPY-SSPSPTAGLSGPFQGMVR------------------------------QKPSLGAMPVQVTPPRGTFSPNMGMQPRQTLNRPPAAPNQLRLQLQQRLQGQQQLMHQNRQAILN-------------------------------------------QFAANAPVGMNMRSGMQQ-QITPQ------PPLN---AQMLAQRQRELYSQQHR----QRQIIQQQRAMLMRHQSFGNNIPPSSGLP--VQMGTPRLPQGAPQQFPYPPNYGTNPGTPPASTSPFSQLAAN----------------PEASLATRSSMVNRGMAG---------------NMGGQFGAGISPQ---------------MQQNVFQYPG-PGLVPQGEATFAPSLSPGSSMVPMPVPPPQSSLLQQTPPTSGYQSPDMKAWQQGTMGNNNVFSQAVQ-SQPAPAQPGVYNNMSITVSMAGGNANIQNMNPMMGQMQMSSLQMPGMNTVCSEQMNDPALRHTGLYCNQLSSTDLLKTDADGNQQVQQVQVFADVQCTVNLVGGDP------------------------YLNQPGPLGTQKPTSGPQTPQAQQKSLLQQLLTE--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15788-1", "uniprot_id": "NCOA1_HUMAN", "id": "Q15788-1", "name": "Nuclear receptor coactivator 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSGLGDSSSDPANPDSHKRKGSPCDTLAS-------STEKRRREQENKYLEELAELLSANISDIDSLSVKPDKCKILKKTVDQIQLMKRMEQEKS---TTDDD-----------------------------------------VQKSDISSSSQGVIEKESLG-------------PLLLEALDGFFFVVNCEGRIVFVSENVTSYLGYNQEELMNTSVYSILHVGDHAEFVKNLLPKSLVN------------------------------------------------GVPWPQEATRRNSHTFNCRMLIHPP-----DEPGTENQEACQRYEVMQCFTVSQPKSIQEDGEDFQSCLICIARRLPRPPAITG-VESFMTKQ---------DTTGKIISIDTSSLRAAGRTGWEDLVRKCIYAFFQPQGREPSYARQLFQEVMTRGTASSP-----------SYRFILNDG-TMLSAHTKCKLCYPQSPDMQPFIMGIHIIDREHSGLSPQDDTNSG-------MSIPRVNPSVNPSISPAHGVARSSTLPPSNSNMVSTRINRQQSSDLH-S-SSHSNSSNSQGSFGCSPGSQIVANVALNQGQASSQSSNPSLNLNNSPMEGTGISLAQFMSPRR-QVTSGLATRPRMPNNSFPPNISTLSSPVGMTSSACNNNNRSYSNIPVTSLQGMNEGPNNSVGFSASSPVLRQMSSQNSPSRLNIQPAKAESKDNKE--------IASILNEMIQSDNS---SSDGKPLDSGLLHNNDRLSDGDSKYSQTSHKLVQLLTTTAEQQLRHADIDTSCKDVLSCTGTSNSASANSSGGSCPSSHSSLTERHKILHRLLQEGSPSDITTLSVEPDKKD--SASTSVSVTGQVQGNSSIKLELDASKKKESKD-------------HQLLRYLLDKD--EKDLRSTP---NLSLDDVKVKVEKKEQMD--PCNTNPTPMTKPTPEEIKLEAQSQFT--ADLDQFDQLLPTLEKAAQLPGLCETDRMDGAVTSVTIKSEILPASLQSAT---------------------ARPTSRLNRLPELELEAIDNQFGQPGTGDQIPWTNNTVTAINQ--------------------------------SKSEDQCISSQLDELLCPPTTVEGRNDEKALLEQLVSFLSGKDETELAELDRALGIDKLVQGGGLDVLSER-------------------FPPQQATPPLIMEERPNLYSQPY-SSPSPTANLPSPFQGMVR------------------------------QKPSLGTMPVQVTPPRGAFSPGMGMQPRQTLNRPPAAPNQLRLQLQQRLQGQQQLIHQNRQAILN-------------------------------------------QFAATAPVGINMRSGMQQ-QITPQ------PPLN---AQMLAQRQRELYSQQHR----QRQLIQQQRAMLMRQQSFGNNLPPSSGLP--VQMGNPRLPQGAPQQFPYPPNYGTNPGTPPASTSPFSQLAAN----------------PEASLANRNSMVSRGMTG---------------NIGGQFGTGINPQ---------------MQQNVFQYPG-AGMVPQGEANFAPSLSPGSSMVPMPIPPPQSSLLQQTPPASGYQSPDMKAWQQGAIGNNNVFSQAVQ-NQPTPAQPGVYNNMSITVSMAGGNTNVQNMNPMMAQMQMSSLQMPGMNTVCPEQINDPALRHTGLYCNQLSSTDLLKTEADGTQQVQQVQVFADVQCTVNLVGGDP------------------------YLNQPGPLGTQKPTSGPQTPQAQQKSLLQQLLTE--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PTD7-1", "uniprot_id": "A0A8M9PTD7_DANRE", "id": "A0A8M9PTD7-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLKMSAAGENALDPNILESRKRKGSPCDTSGP-------SVEKRRRELECRYIDELAELLSANMSDIASLNVKPDKCHILKSTVDQIQQIKRREQENAALMSPNDE-----------------------------------------VQQSDISSSSHGMVEKEALG-------------PLLLEALDGFFFVVNREGRIVFVSENVTGYLGYTQEELMTSSVYSILHVGDHNEFVRILLPKSLVN------------------------------------------------GVPWSQEQGRRNSHTFNCRLLKRPP-----DEVDSENQEARQQYELMQCFTVSQPKALQEEGEDLQSCLICIACRIPRPPQIPVSTESFITKQ---------DPTGKIISIETSALRATGRPGWEDLVRKCIYAFFQPQGNEPSHAKKLLHEVMTHGMAISP-----------LYRFTLSDG-TSLSAQTRCKFCCPQNPDVQPFIMGFHTIDREHNTASSQENTTPS-------LSSPAAPPSRSPALQPSSDLS----IHLNNTNGTCATPGPLTPT---------------------PPGYLTPSRVGPSQ-----QVSSPSP--LGSPLTAT---PTSFMSPRPPRGSPGLASSPRVPGHPFSPSTPSIHSPAGG----------------LTRQQSGGDG----VGFSLPSPLPPRQTPTPSSSPARQPPAKPPEASNDE--------PKSN-----QVGNP---------------------------------KLSQLLDGASAPEQ-------------------DSQPRPSPTSQCPASHSSLTERHKILHRLLQDNSPADAG---KEPDIKKEPPTSPNSALIARGLG-------------KEPQD-------------HQLLRFLLDTD--EKDLEDLPPPATLSLQTVKVKAEKKGSRENVSCAAALANNAMPGSPQSSGKASPQFPS-TDLDTLNQLLPTLRASVGGKTVEEPS-EDSLSIGVNVKRESPGTSSQAFPDGENLSSQTSFDFCDPSTPNQGQSQVQVSDLGQTELFQPPKESSSPFASPTSHNSFNTNTGLAKLELPDSQQFQALPLVEPMTFDNSLANQTQAPLSSPQEQCVPCPLDEMLCPPTTPEGRNDEKALLEQLVTFLSHTDESELAELDRALGIDKIVQSGCLEPVTQTP------------------FPQSQPPTPVPLDPKLPSYPSQFPTSPSQFPAEMATAQGMSF------------------------------GAP-------RMPFPGNVVQAGMNRAPG-VSNQLRLPPNQLRLQLQQRLQGPQQLQN--RLAAMG-------------------------------------------SFPQGGHVAMGMRQSIQQPQMPSQ------PPLN---AQMMAQRQREVYSYQHR----QRQLLQQK-VMLMR-QGINTGPLGAQRLPKGPQQQQQQPPPQQQQQFGFPPGYNAVPGNTPTSPSHFNPMGGP----------------LDPKLSVRAGLGNQGIMG---------------AIQGQFGGPVNTP---------------VQQGLFQQFGGSGMIQQADPSFAPELSPTSPLLSPQNSTSQSPLLQQTQPPPGYQSPDLKTWQQGTVANNGMYNQVGPPVSQSFGQQGVYNNMSITVSMAGGSGAVNTLPPIGPSVGMGNNNLGNVTTMC-------------------------------NEQVQQVQVFADVQCTVNLVGSDS------------------------YLNQSGPIGSQKGPSGTPSAQSQQKSLLQQLLTE--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9ND53-1", "uniprot_id": "M9ND53_DROME", "id": "M9ND53-1", "name": "", "aln": "MSIAAAENAGLSPSDLPDHWASGTSNPSTSTSSSSSSSISASGSNNNKYNSGNISVCNLPRSSPAAATAAVTLSSAAGGIGSNLLSGLHHGLAPGTHPLQRATAASGGGAGAGGVAGASTAAALTLQQHQHQQQQQQQQQQAQHQHQHQHQQQTQQQQLAYQHQQLQQQIISHRSIQNKAAATAAAQTANLAAALQRSAAIMNAVASPISANSANSATSGRKIRRKTDSKVNLPQSQINKCNNEKRRREAENGYIEQLSEILTLNK-RGDMTSTKPDKAAILNQVVRTYREICDKGQNRDISSTSTNNNNSTTTTNNNTNSNNNNNTSKPQATSTRCSRCATDNCSIHPVQQGEVSSTEPPLPEPSLLLGQVPEISAYFEALEHYISGVGWVLLQVNANGIIESCTQNIRDLIGYEKQELYHQPLYMYLYSGDHAKLEPIINTMYNNPNGGNSNSANNSGPGGSSAGTSAGVWGDLEELNNGNASQGSNSSGAGGLGGAGGAAAGKKRSISTKVRMLVKDTRTATQTSSNCEEKPLRQSGHQDKYEEVVLIAAPVKDDADASSSVLCLITRPEDESPLEINIQQHVQQQPIEQMTFKLDIHGKILTLDPTALREPFKQHLQTWVGRLWQDLCHP--HDLSTLKSHLRDIQDSASANSPGAGAGTSVVSRPFRLRLGAPDVYVHVKANSRLFLNQTPGEGDFIMSVQTLLNSENDMNSSNTGAGSGGLGLGQLCAMAPSPSLASSLLSSLSMDGLHGGTGSGSSSSPAASGMLPTHLLGGLVGGGQQGGGGNSTQTTSVGGPLMSSAIINGTGLQQQQQQQQRSGASSSASSSANALVNAFTASPAPAEHSFYGSDTFEFDIAAHSSSFELDPSGGVGAWTDSRPNSRASVATPVSTPRPPSGHGFSPAVCASPATPYQLSSHSAASLPSPQSNASAGGGNYGGFNFHSFDSSDVKPEKDVQQQQNQQQSNNNSSSSNPLLGGGLPNGVGGMLLSQQQQQQQTPPQQQQQQQQQESSERLRHLLTKSQSMAGGLGGLGDDEKYFKPEGSEEEKHASGGFKMGGQPGGMGMFGPMGSMGRGVGNSSMLHKAGNSQNPMLLKLLNEKSEDDDGNGSGGGPGSMNNSRQSELMRQLKNPDGGSHGMHRNSASGNMSTEDLKAMLKIQSDPSLNRKRSLNEPDDDPSAKRSEDKPSKLCTQNKMLAKLLQNPPKIPKAPNPEQPLQVKTLPDITSSTVSSTLAAPGNLISAG-------------STGPKAAANRNRKQQQQQQQQQQQQQQQQVAGIPSQQQQQQPNDVYLSQQQQQQLQSPQ------------LAFQHQQLATTATTSITTAASTSAAAAAAAAILGEGDSELSKLLDSVMEYYPDDTPIVTNAPSEASAINDIQKSLMLDVESAAFGNDLNQQLMMTQQQQHQQQQQQQQLLALQLAQQQQQQRQQHLQQPPAYPGMLNMQQQQHQQQQQQNQQHIMQRLEAMRNQGNQGFQRPPPMYPARGRGPMNAVATPGGVVLPAQQQLRNIRQQQQLAAAQQKERLLQQQQKQQLLVPENASEYWGNSNLQLIIKLIVSYILAGMNAGLNNIGSLLNTTGAPNVSLSRTNLPSDAQLSPNFAQTLMQQQLSPGRSAPYSPQPNQGYAPQFPQPGQRLSPQQQQQLSQQQQNNVQQQQLAYQQQQVGDGGRSNTPFGSNSGMQSPGMQ-NSPQQWGSGGGGGGGPGGPLPSGNAGRTLQQHNPMLIAQLQGVSPYNARQYQQNQRRGLNSPGAVGPGGNPAAQAALQRQNSFQGQGGGGATTPDGSGVGFGGPQSPYGTNVNVFQQQQLQRLQRQGSVPQATQHLPGSPRFG--SSPGSSNNTDSSAAAGNQQQQQQQQQQQQQQHQQQQHQQLMNGLSMSPHPHPHPAMMGVGGMGSGGGNGIIGLGGGGGNYGATLGGYGQSQQANDFYGRAQTAGGGGSVAGGNANSEFVKQELRAVVSVRAQQAAAAATGGAGVGGGVAQRGQTPQSPLQQGSVIGGGGGIVGGVNSTNTMGNVTPTGSGNVSNSMLNTPPDPTLSFSFETPDFFTSSATR", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . .: :. : *: : ... . . ****** * *:::*:*:*: * ..****. **:..* : : *:. :. :: **:.::**:. : * . * :..:. .:: ** :* * ::*: . :** ::** .:* *: *** :: : . * . ::.* : : *:* : . . . *:: * . : * : ::. * .*.::*: * . : :..: :* * ***::::.::** . : : * : : :* .: * :. :::: . * ** :*: *. . : .::..:: *.*. ***..: : .... ...: . :. ** ..: .: .: .... : . . . * : . . * .. . .*. .: . ::. .: . . . . . .* * . . ** . *.: ::. ... * : : : * : . . . .. *.:: : ..*.. . *. .. . .: :. :*:* * : * .:.:. . .:. : :*. : : . . : * . . . :.. . * : * *.: : : . . .. . . . : : . : : :: . : . :. : ... . . ... ** .: . **:.:: : . ..* .*:.: :. *: : .* .: : : . . .*. . * * . . . . :: .. * : :* *: * * * . .:. . :. .: . : * *:.. * * * :.* :.: . *:: *:* *: : : * .. . : **: . . ** . .* . : : . * .: . * * : ** * .. : .:** : *.. *.. * *. . .. .* :.: .. . *. : : ** :: ..* . : *.: :**. : : . .*: *. * . ..: *. . :*....:*. . ... .:: :: : *: ", "identical_positions": 157, "similar_positions": 427, "identity": "7.56%" }, { "cls_id": "homologset.agr.RGD:1309047", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4A098-1", "uniprot_id": "D4A098_RAT", "id": "D4A098-1", "name": "", "aln": "TMEGQAVPGVGDWEIDVESLELEEDGCGTPLRATP-QEPSPSTADGEEDEDEEEEDEDAEDEGEGEDSSASPEVPGRPEQPGGLAPRPPPAAQALPAAAVVPERGVTAGGGAEPRKLSRTPKCARCRNHGVVSCLKGHKRFCRWRDCQCANCLLVVERQRVMAAQVALRRQQATEDKKGLSGKQNNFDRKAVYQRQVRAPSLLAKSILEG---YRPMTAAETYLGGTLPLPPPVSDRMRKRRAFADKELENIMLEREYKEREMLETSQAAALFLPNRMVPGPEYSSYKGAFSPSAGELPSKDFCNFLPTCLDLTMQYSGSGNMELISSNVSVATTYRQYPLSSRFLVWPKCGPISDTLLYQQYLLNATTSVQALKPGAGWDLKGTRVQDGLSAEHDGMPPKPEGSLVLPQLSEVPTSRTDLQAHQAVPERSAFSPPSRNFSPIVDMDCLAAQGHVLTKISKENTRYPLPLKRNPFHSVFQPTLNDKSGPELKAPFVKEAFEETPKKHRECLVKENPKYTFTIDRCAKDLFVAKQVGTKLSVNEPLSFSVESILKRPSSAVTPVSQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BG36-1", "uniprot_id": "DMRT2_MOUSE", "id": "Q8BG36-1", "name": "Doublesex- and mab-3-related transcription factor 2", "aln": "MTEGQAVPGVGDWEIDVESLDLEEDSCGTPLRATPPQEPSPAAADGEEDEDEEEEDEDVEDEGDGEEPGVSSEVPGRPEQPGGLAPRPPPAAQALPAAAAAPERGATAGGGAEPRKLSRTPKCARCRNHGVVSCLKGHKRFCRWRDCQCANCLLVVERQRVMAAQVALRRQQATEDKKGLSGKQNNFDRKAVYQRQVRAPSLLAKSILEG---YRPMT-AETYLGGTLPLPPPVSDRMRKRRAFADKELENIMLEREYKEREMLETSQAAALFLPNRMVPGPEYSSYKGTYSPTAGELPSKDFCNFLPTCLDLTMQYSGSGNMELISSNVSVATTYRQYPLSSRFLVWPKCGPISDTLLYQQYLLNATTSVQALKPGTGWDLKGTRVQDGLSAEQDMMPPKLEGSLVLPHLPEVPASRTDLQVHQVVPERSAFSPPGRNFSPIVDMDCLAAQGHVLTKLSKENTRPSLPLKTNPFHSVFQQTLSDKSGPELNAPFVKEAFEETPKKHRECLVKESQKYTFTIDRCAKDLFVAKQVGTKLSANEPLSFSVESILKRPSSAVTHVSQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y5R5-1", "uniprot_id": "DMRT2_HUMAN", "id": "Q9Y5R5-1", "name": "Doublesex- and mab-3-related transcription factor 2", "aln": "MADPQAGSAAGDWEIDVESLELEEDVCGAPRSTPPGPSPPPADGDCEDDEDDDGVDEDAEEEGDGEEAGASPGMPGQPEQRGGPQPRPPLAPQASPAGTGPRERCTPAGGGAEPRKLSRTPKCARCRNHGVVSCLKGHKRFCRWRDCQCANCLLVVERQRVMAAQVALRRQQATEDKKGLSGKQNNFERKAVYQRQVRAPSLLAKSILEG---YRPIP-AETYVGGTFPLPPPVSDRMRKRRAFADKELENIMLEREYKEREMLETSQAAALFLPNRMVPGPDYNSYKSAYSPSPVEPPSKDFCNFLPTCLDLTMQYSGSGNMELISSNVSVATTYRQYPLSSRFLVWPKCGPISDTLLYQQCLLNATTSVQALKPGASWDLKGARVQDGLSAEQDMMPSKLEGSLVLPHTPEIQTTRSDLQGHQAVPERSAFSPPRRNFSPIVDTDSLAAQGHVLTKISKENTRHPLPLRHNPFHSLFQQTLTDKSGPELKTPFVKEAFEETPKKHRECLVKDNQKYTFTIDRCAKDLFVAKQVGTKLSVNEPLSFSVESILKRPSSAITRVSQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VYE0-1", "uniprot_id": "Q9VYE0_DROME", "id": "Q9VYE0-1", "name": "", "aln": "MHFDETRSPNKDVRIGKSQRLAANGRQGTDPESDPLHARCVVPHASTPRGRRIPWGHNDDDD-DGNHLTLPDSLTATSSCGCQCLNVRAPFHILLVDQQARMSKDASVRICQRERRLLRTPKCARCRNHGVISCVKGHKRLCRWRECCCPNCQLVVDRQRVMAAQVALRRQQTMEALEATASSTKSTG--------VTTASANNSSSSEGEDSLS-------------------------------------------------------------STSPPPAHSHPHSHSHPTS------------------------------CVSNSSSSSATRQALMAQKRIYKQRLR------SLQQSTLHITAAMEEYKQ--RFPTFSSPLMERMRKRRAFADPELN------HVMEATLGGNALYFATVAAAAAACAP-------------VHQEQHIYHPMP-----PTIPLTIPPTN------------PAMTTPAVTTASTGSGKKP------------------------------------KLSFSIESIMGIST--------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: . * .*. .. :. *: : * ..: ::: :*:. . :.. .. . .: ... . *:* *************:**:*****:****:* *.** ***:***************: * :. :.. :. * :.* .* ** * * :. :. *:. ** * ::: ** ::.: : : ** *: *:::: * : .: : : : .: .: : : * . * ... :* :* : : *: :. .:** * : * :.:* *. * : ** ****:***: .: ", "identical_positions": 93, "similar_positions": 106, "identity": "16.46%" }, { "cls_id": "homologset.agr.RGD:1309048", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BP86-1", "uniprot_id": "SNPC4_MOUSE", "id": "Q8BP86-1", "name": "snRNA-activating protein complex subunit 4", "aln": "---------------------------------MDIDAEREKITQEIQELERILYPGSTSVHFEVSESSLSSDSE-----ADSLPDEDLETAGAPILEEEGSSE-------------------SSNDEEDPKDKALPEDPETCLQLNMVYQEVIREKLAEVSQLLAQNQEQQEEILFDLSGTKCPKVKDGRSLPSYMYIGHFLKPYFKDKVTGVGPPANEETREKATQGIKAFEQLLVTKWKHWEKALLRKSVVSDRLQRLLQPKLLKLEYLHEKQSRVSSELERQALEKQIKEAEKEIQDINQLPEEALLGNRLDSHDWEKISNINFEGARSAEEIRKFWQSSEHPSISKQEWSTEEVERLKAIAATHGHLEWHLVAEELG--TSRSAFQCLQKFQQYN-KTLKR--KEWTEEEDHMLTQLVQEMRVGNHIPYRKIVYFMEGRDSMQLIYRWTKSLDPSLKRGFWAPEEDAKLLQAVAKYGAQDWFKIREEVPGRSDAQCRDRYIRRLHFSLKKGRWNAKEEQQLIQLIEKYGVGHWARIASELPHRSGSQCLSKWKILARKKQHLQRKRGQRPRHSSQWSSSGSSSSSS------EDYGSSSGSDGSSGSENSDVELEASLEKSRALTPQQYRVPDIDLWVPTRLITSQSQREGTGCYPQHPAVSCCT---QDASQNHHKEGSTTVSAA--EKNQLQVPYETHSTVPRGDRFLHFSDTHSASLKDPACKS-----------------------HTLMKERPKQPLLPSSRSGSDPGNNTAGPHLRQLWHGTYQNKQRRKRQALHRRLLKHRLLLAVIPWVGDINLACTQAPRRPATVQTKADSIRMQLECARLASTPVFTLLIQLLQIDTAGCMEVVRERKSQPPALLQPGTRNTQPHLLQASSNAKNNTGCLPS-MTGEQTAKRASHKGRPRLGSCRTEATPFQVPVAAPRGLRPKPKTVSELLREKRLRESHAKKATQALG-LNSQLLVSSPVILQPPLLPVPHGSPVVGPATSSVELSVPVAPVMVSSSPSGSWPVGGISATDKQP-----------------------PNLQTISLNPPHKGTQVAAPAAFRSLALAPGQVPTGGHLSTLG--QTSTTSQKQSLPKVLPILRAAPSLTQLSVQ---------PPVSGQ-------PLATKSSLPVNWVLTTQKLLSVQ----------------VPAVVGLPQSVMTPETIGLQAKQLPSPAKTPAFLE----------QPPASTDTEPK------------------------------------------------------------------------------------GPQGQEIP----------------------------PTPGPEKA-----------------------------------------------ALDLSLLSQESEAAIVTWLKGCQGAFVPPLGSRMPYHPPSLCSLRALSSLLLQKQDLEQKASSLAASQAAGAQPDPKAGALQASLELVQRQFRDNPAYLLLKTRFLAIFSLPAFLATLPPNSIPTTLSPDVAVVSESDSEDLG-DLELKDRARQLDCMACRVQASPAAPDPVQSHLVSPGQRAPSPGEVSAPSPLDASDGLDDLNVLRTRRARHSRR-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1LYZ6-1", "uniprot_id": "F1LYZ6_RAT", "id": "F1LYZ6-1", "name": "snRNA-activating protein complex subunit 4", "aln": "---------------------------------MDIDAEREKVTQEIQELERILYPGSSSVHFEVSESSLSSDSE-----ADPLPDEDLETAGAPVLEEERSSE-------------------GSNDDEDPKDKALPEDPETCLQLNMVYQEVIREKLAEVSQLLAQNQEQQEEILFDLAGTKCPKVKDAKSLPSYMYIGHFLKPYFKDKVTGVGPPANEETREKAAQGIKAFEQLLVTKWKHWEKDLLRKSVVSDRLQRLLQPKLLKLEYLQEKQSRVSSELEKQALEKQIKEAEKEIQDINQLPEEALLGNRLDSHDWEKISNVNFEGARSAEEIRKFWQSSEHPSINKKEWSTEEVERLKTIAASHGHLEWHLVAEELG--TSRSAFQCLQKFQQYN-KALKR--KEWTEEEDHMLTQLVQEMRVGNHIPYRRIVYFMEGRDSMQLIYRWTKSLDPSLKRGFWAPEEDAKLLQAVAKYGAQDWFKIREEVPGRSDAQCRDRYIRRLHFSLKKGRWDAKEEQQLIQLIEKYGVGHWARIASELPHRSGSQCLSKWKILARKKQHLQKRRGQRSRHSSQWSSCSSSSSSSSSSSGSEDYGGGS-SSSSNSSEDSEVELEEPLQNSRALAPQQYSVPDIDLWVPTRLIDSRSQREETGCYPVHPAVSCR-------TQNHHKEGSTVVSAP--ERNQMQECCETHSTVPRGVQSLHSSDTHGASVKEPACKS-----------------------HTLVKERRRQPPLPNSRSGSDPGNSMAGPHLRRLWHGTFQNKQRRKRQALHRRLLKHRLLLAVIPWVGDINLACTQAVQRPAAVQTQADSIRMQLECARLASTPVFTLFIQLLQIDTAGCMEVVQERKTQPPALLQPGTRNTQPHLLQASSNAKNNTGCLLPGMLDEQTAKRTSQKGRPRLGSCKAEATPFQVPVAAPRGLRPKPKTVSELLREKRLRESHAKKATQALTALSSQLLVSSPVLLQPPLLPAARGSPVVGPAASSVELSVPVAPVMVSSSPSGSWQVGGISATDKQP-----------------------PNLQTIPLNPSHKGTQIAAPAAFRSLALASGHVSTGCPLNTLG--QTSTTSQKQSLPKVLPILPAAPSLTQLSVQPLSLPPVLNPPASGQ-------PPATKSSLPVSWVLTTQKLLSVQ----------------VPAVVGLPQPVTTPETIGLQAKQLPSPSKTPAFLG----------QPPASTDTEPK------------------------------------------------------------------------------------GPQGQQTP----------------------------PTPGPEKK-----------------------------------------------ALDLSLLSQESEAAILTWLTGSQGACVPPLGSRMSYHPPSLCSLRALSSLLLHKKDLEQKASSLVAGQAAGAQPEPKAGALQASLELVQRQFQNNPAYLLLKTRFLAIFSLPAFLATLPPNSVPTTLSPAMAVGSESDSEDFG-DLEPRDGATQLDCMACRVRANLMAPDPVVSHLPSWERRAPSPSAVSAPSHLDASDDLDDLDVLRTRHARHSRK-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5SXM2-1", "uniprot_id": "SNPC4_HUMAN", "id": "Q5SXM2-1", "name": "snRNA-activating protein complex subunit 4", "aln": "---------------------------------MDVDAEREKITQEIKELERILDPGSSGSHVEISESSLESDSE-----ADSLPSEDLDPADPPISEEERWGE-------------------ASNDEDDPKDKTLPEDPETCLQLNMVYQEVIQEKLAEANLLLAQNREQQEELMRDLAGSKGTKVKDGKSLPPSTYMGHFMKPYFKDKVTGVGPPANEDTREKAAQGIKAFEELLVTKWKNWEKALLRKSVVSDRLQRLLQPKLLKLEYLHQKQSKVSSELERQALEKQGREAEKEIQDINQLPEEALLGNRLDSHDWEKISNINFEGSRSAEEIRKFWQNSEHPSINKQEWSREEEERLQAIAAAHGHLEWQKIAEELG--TSRSAFQCLQKFQQHN-KALKR--KEWTEEEDRMLTQLVQEMRVGSHIPYRRIVYYMEGRDSMQLIYRWTKSLDPGLKKGYWAPEEDAKLLQAVAKYGEQDWFKIREEVPGRSDAQCRDRYLRRLHFSLKKGRWNLKEEEQLIELIEKYGVGHWAKIASELPHRSGSQCLSKWKIMMGKKQGLRRRR-RRARHSVRWSSTSSSGSSS-------GSSGGSSSSSSSSSEEDEPEQAQAGEGDRALLSPQYMVPDMDLWVPARQSTSQPWRGGAGAWLGGPAASLSPPKGSSASQGGSKEASTTAAAPGEETSPVQVPARAHGPVPRSAQASHSADTRPAGAEKQALEGGRRLLTVPVETVLRVLRANTAARSCTQKEQLRQPPLPTSSPGVSSGDSVARSHVQWLRHRATQSGQRRWRHALHRRLLNRRLLLAVTPWVGDVVVPCTQASQRPAVVQTQADGLREQLQQARLASTPVFTLFTQLFHIDTAGCLEVVRERKALPPRLPQAGARDPPVHLLQASSSAQSTPGHLFPNVPAQEASKSASHKGSRRLASSRVERTLPQASLLASTGPRPKPKTVSELLQEKRLQEARAREATRGPVVLPSQLLVSSSVILQPPLPHTPHGRPAPGPTVLNVPLSGPGAPAAAKPGTSGSWQEAGTSAKDKRL-----------------------STMQALPLAPVFSEAEGTAPAASQAPALGPGQISVSCPESGLGQSQAPAASRKQGLPEAPPFLPAAPSPTPLPVQPLS-----LTHIGGP-------HVATSVPLPVTWVLTAQGLLPVP----------------VPAVVSLPRPAGTPGPAGLLATLLPPLTETRAAQGPRAPALSSSWQPPANMNREPEPSCRTDTPAPPTHALSQSPAEADGSVAFVPGEAQVAREIPEPRTSSHADPPEAEPPWSGRLPAFGGVIPAT------EPRGTPGSPSGTQEPRGPLGLEKLPLRQPGPEKGALDLEKPPLPQPGPEKG-----------------------------------------------ALDLGLLSQEGEAATQQWLGGQRGVRVPLLGSRLPYQPPALCSLRALSGLLLHKKALEHKATSLVVGGEA----ERPAGALQASLGLVRGQLQDNPAYLLLRARFLAAFTLPALLATLAPQGVRTTLSVPSRVGSESEDEDLLSELELADRDGQPGCTTA----------------TCPIQGAPDSGKCSASSCLDTSNDPDDLDVLRTRHARHTRKRRRLV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3ASS0-1", "uniprot_id": "A0A8M3ASS0_DANRE", "id": "A0A8M3ASS0-1", "name": "", "aln": "MTHLSRDSWLYTHDVQVTYNSFIKVSPCPKMASDDLRAQRDKIQREILALESTLGADSSIADQLSSDNSSDYESDDSGPTVKRVERDDLETERLRIQREIEELENALGADAALENVLQDSDHDTDSSEDSADDLELPQNVETCLQMNLVYQEVLKEKLAELEQLLIENQQQQKEIEVQLSGPGNSIFSVPGVPPQKQFLGYFLKPYFKDKLTGLGPPANEETKERMKHGSIPVDNLKIKRWEGWQKTLLTNAVARDTMKRMLQPKLSKMEYLSNKLCRAEGE-EKEQLKAQIELIEKQIAEIRTLKDDQLLGDLQDDHDWDKISNIDFEGLRQADDLKRFWQNFLHPSINKSVWKQDEIYKLQAVAEEFKMCHWDKIAEALG--TNRTAFMCFQTYQRYISKTFRR--THWTEEEDDLLRELVEKMRIGNFIPYIQMSHFMVGRDGSQLAYRWTSVLDPSLKKGPWSKEEDQLLRNAVAKYGTREWGRIRTEVPGRTDSACRDRYLDCLRETVKKGTWSYAEMELLKEKVAKYGVGKWAKIASEIPNRVDAQCLHKWKLMTRSKKPLKRPLSSITTSYPRNKRQKLLKTVK----EEMFFNSSSDDESQINYMNSDESDDLAEDENLEIPQKEYVQTEMKEWIPRNAMVWTITPGSFRTLWVRLPTNEEE-----------LRESTKESGLGSDSSENSACPNDEPIMERNTILDRFGDVERTYVGMNTVVLHR-------------------------RTDDEKAMFKVCMSDVKQFIQMKATEFAVKKKKKIKNKKRTLRDVFS---LNTDLQKAVIPWIGNVIISIPAN----EAIFCEGDVVGIKAASIRLQKTSVFTFFIKAFHVDVNGCRTVIEIHKKLDIKMPLAINGNPKPTPISTSP--KTVAVLLQQSKAASEHKKPAEPSQQPSLPPSQKPSLPPSVPPSQQPTLPPPSQLSQPPPQPPSLPPSQPPAQQPSLPPPQPPSLPPPLPPPQPPSLPTSQQQSLPPSQQPSLPPSQQHSLPPFQNPSLPPSQQPSLPPSKQPPQPLPVRQITTPTLIYPNNLVITNPNMEGEVQHLVFKGLLLPQQPSKAVSHIPLPVMQPKTPAQPIVVSKSPSVQDSNSVKSSKRICKPTKKAQALMEQSKVKSRKKEPQKQNQGNKNVVFPTVTLQTSPVIKILSPARLVQVTGLSPNFSSNQTINMPDKSLTIKSPQPCSSGNLHQSAPVVVHSSTNPTFVHSSVSNVSRDNLNVSSTINISPRVSRDALNPTSFLNSTTFPLPQNLSVQQSVQIVPQIPINVVHKATCTKAAKTSSDSSSDESVVKQHQSSPSTGRSIPPAVFNIQPNPSTPPTLSSGPVIFNPNNKVVAPKLCGLNVSSSQLPTVSTQKTKYRPIRPLGPLPVVAPPSRKVTSMSRIRAQSEGEPLISLRELPAAGVNFDSHLIFPEKSSEVDDWMDGKGGIPLPHLDTSLPYLPPSAATIKTMTDLLRAKQPLLLAAKKVLP--AQYQDECNEEVEVEAIRKVVAERFASNPAYLLCKARFLSCFTLPALLATINPCEERQLLSEDDEEDDHLATINPSEERQSSTEDDEEDLQTN-----------------ERSQPPTARTELNMNENEASAKQFSGIGPKRQRNQRIKRLIK---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VHX0-1", "uniprot_id": "Q9VHX0_DROME", "id": "Q9VHX0-1", "name": "", "aln": "-----------------------------MDDADDLRINQQQLMDEISALLQNTAKPSAANALQLN-------------------------------------------------------------------QELQRRLMQVRTKILAMLQVVRARFSRNEDILVRRLRPRSHFGPNSLNLSGAILRKGTFR--------FKGNLFFRDIDGRSCPNNEDYEARCHTEMFPTDFDMHS--RHVWTLLDKKNVIMGIKQQLLEHRAHSTNALP------SGSLKRKPIER----------HLSTLVSLLATADSSFSIDWNQISTLDLEYRHSPYSCEAMWRVYLTPDLRRDDWSPEEDETLLAVATANRMQNWELIAASLDRRSDYQCFVRFHTALRFLLEPKNS--HRWSEEDNDKLRAIVDRNTANSVINWKKVVEYFPDKSKSTLIGRYYYVLHPSISHEPFTTKEDMMLFAAVEEYNGKFHCFPRSLFPNRSLTQLRTRYHNVLAQRNKTDSWSVQDDTRLMSFVTQYGASQWLNCATFLGNHTRTSCRTRFLVIKKFLE--------------------------------------------QNPNAKVEDLPRRRSKKVSLVNSDNWAQRLQEWQEDPESLVNDNP----------------------------PKGTRVRGPKSKKARIERQAESFSRLSKVDIEFCN----------------------------------------------------------------------------------------------------FFKFSYNLTLSTPKTFPVPKDVYNLAYVIRALAYKPPIRPSLLQNIFMPN---------DVLKCYNSMIRNLPDEEGDMKSPLLPPNWSTMMGFRALCILSGDCRKDTETRSFEYNESLPPIQLFRKRLQALFYRTTLLSRLESQLFTDLPSALVSLPRPKHDYAKMG----------------THVELIDPEPAPQNDLKSEPLSENEVINTVKQELEMEYTVP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P22035-1", "uniprot_id": "BAS1_YEAST", "id": "P22035-1", "name": "Myb-like DNA-binding protein BAS1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------MSNISTKDIRKSKPKRGSGFDLLEVTESLG------------------YQTHRKNGRNSWSKDDD---------------------------------NMLRSLVNESAKELGYEN---------------------------GLEDVKTIQQSNHLSKCIAWDVLATRFKHTVRTSKDVRKRWTGSLDPNLKKGKWTQEEDEQLLKAYEEHG-PHWLSISMDIP---GRTEDQCAKRYIEVLGPGSKGRLREWTLEEDLNLISKVKAYGT----KWRKISSEMEFRPSLTCRNRWRKIITMVVR-GQASEVITKAIKENKNIDMTDGKLRQHPIADSDIRSDSTPNKEEQLQLSQQNNPSLIKQDILNVKENESSKLPRLKDNDGPILNDSKPQALPPLKEISAPPPIRMTQVG---------------------------------QTHTSGSIRSKVSLPIEGLSQMNKQSPGGISDSPQTSLPPAFN-----------------------------------PASLDEHMMNSNSISDSPKHAYSTVKTREPNSSS-----------------------------------------------------------------------------------------------------TQWKFTLKDGQGLS-------ISNGTIDSTKLVKELVDQAKKYSLKISIHQHIHNHYVTSTDHPVSSNTGLSNIGNINGNPLLMDSFPHMGRQLGNGLPGLNSNSDTFNPEYRTSLDNMDSDFLSRTPNYNAFSLEATSHNPADNANELGSQSNRETNSPSVFYPQAN-----------TLIPTNSTATNNEIIQGNVSANSMSPNFNGTNGKAPSSTASYTTSGSEMPPDVG---------------------------------PNRIAHFNYLPPTIRPHLGSSDATRGADLNKLLNPSPNSVRSNGSKTKKKEKRKSE-----------------------------------------------------------------------SSQHHSSSSVTTNKFNHIDQSEISRTTSR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SDTPLRDEDGLDFWETLRSLATTNPNPPVEKSAENDGAKPQVVHQGIGSHTE------------DSSLGSHSGGYDFFNELLDKKADTLHNEAKKTSEHDMTSGGSTDNGSVLPLNPS----------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::. . .. . : : . * . ::: . : ::: . : : . *: ::. . : . . . * *.: : *. :* * .* :: : . : . . .*: *:: * *. : :: : : *: : : : : : . : . * :.. : . . : : : ... : . . . . . .: . . . : : : . : : .: : . . . . ... . . . ", "identical_positions": 14, "similar_positions": 106, "identity": "0.84%" }, { "cls_id": "homologset.agr.RGD:1309050", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9P2Q2-1", "uniprot_id": "FRM4A_HUMAN", "id": "Q9P2Q2-1", "name": "FERM domain-containing protein 4A", "aln": "----------------MAVQLVPDSALG-----------------LLMMTEGRRCQVHLLDDRKLELLVQPKLLAKELLDLVASHFNLKEKEYFGIAFTDETGHLNWLQLDRRVLEHDFPKKSGPVVLYFCVRFYIESISYLKDNATIELFFLNAKSCIYKELIDVDSEVVFELASYILQEAKGDFSSNEVVRSDLKKLPALPTQALKEHPSLAYCEDRVIEHYKKLNGQTRGQAIVNYMSIVESLPTYGVHYYAVKDKQGIPWWLGLSYKGIFQYDYHDKVKPRKIFQWRQLENLYFREKKFSVEVHDPR-RASVTRRTFGHSGIAVHTWYACPALIKSIWAMAISQHQFYLDRKQSKSKIHAARSLSEIAIDLTETGTLKTSKLANMGSKGKIISGSSGSLLSSGSQESDSSQSAKKDMLAALKSRQEALEETLRQRLEELKKLCLREAELTGKLPVEYPLDPGEEPPIVRRRIGTAFKLDEQKILPKGEEAELERLEREFAIQSQITEAARRLASDPNVS-KKLKKQRKTSYLNALKKLQEIENAINENRIKSGKKPTQRASLIIDDGNIASEDSSLSDALVLEDEDSQVT--STISPLHSPHKGLPPRPPS-HNRPPPPQSLEGLRQMHYHRNDYDKSPIKPKMWSESSLDEPYEKVKKRSSHSHSSSHKRFPSTGSCAEAGGGSNSLQNSPIRGLPHWNSQSSMPSTPDLRVRSPHYVHSTRSVDISPTRLHSLALHFRHRSSSLESQGKLLGSENDTGS---PDFYT--PRTRSSNGSDPMDDCSSCTSHSSSEHYYP-AQMNANYSTLAEDSPSKARQRQRQRQRAAGALGSASSGSMPNLAARGGAGGAGGA--GGGVYLHSQSQPSSQYRIKEYPLYIEG-GATPVVVRSLESDQEGHYSVKAQFKTSNSYTAGGLFKESWRGGGG----DEGDTGRLTPSRSQILRTPSLGREGAHDKGAGRAAVSDELRQWYQRSTASHKEHSRLSHTSSTSSDSGSQYSTSSQSTFVAHSRVTRMPQMCKATSAALPQSQRSSTPSSEIGATPPSSPHHILTWQTGEATENSPILDGSESPPHQSTDE------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BIE6-1", "uniprot_id": "FRM4A_MOUSE", "id": "Q8BIE6-1", "name": "FERM domain-containing protein 4A", "aln": "------------------------------------------------MTEGRRCQVHLLDDRKLELLVQPKLLAKELLDLVASHFNLKEKEYFGIAFTDETGHLNWLQLDRRVLEHDFPKKSGPVVLYFCVRFYIESISYLKDNATIELFFLNAKSCIYKELIDVDSEVVFELASYILQEAKGDFSSNEVVRSDLKKLPALPTQALKEHPSLAYCEDRVIEYYKKLNGQTRGQAIVNYMSIVESLPTYGVHYYAVKDKQGIPWWLGLSYKGIFQYDYHDKVKPRKIFQWRQLENLYFREKKFSVEVHDPR-RASVTRRTFGHSGIAVHTWYACPALIKSIWAMAISQHQFYLDRKQSKSKIHAARSLSEIAIDLTETGTLKTSKLANMGSKGKIISGSSGSLLSSGSQESDSSQSAKKDMLAALKSRQEALEETLRQRLEELKRLCLREAELTGKLPVEYPLDPGEEPPIVRRRIGTAFKLDEQKILPKGEEAELERLEREFAIQSQITEAARRLASDPNVS-KKLKKQRKTSYLNALKKLQEIENAINENRIKSGKKPTQRASLVIDDGNIASEDSSLSDALVLEDEDSQVT--STISPLQSPHKGLPPRPPSSHNRPPPPQSLEGLRQLHYHRTDYDKSPLKPKMWSESSLDEPYEKVKKRSSHGHSSSHKRFPSTGSCTEAG-VSSSLQNSPIRSLPHWNSQSSMPSTPDLRVRSPHYVHSTRSVDISPTRLHSLALHFRHRSSSLESQGKLLGSENDTGS---PDFYT--PRTRSSNGSDPMDDCSSCTSHSSSEHYYP-AQMNANYSTLAEDSPSKARQRQRQRQRAAGALGSASSGSMPNLAARSGAASTG-----GGVYLHSQSQPSSQYRIKEYPLYIEG-SATPVVVRSLESDQEGHYSVKAQFKTSNSYTAGGLFKESWRGGG-----DEGDAGRLTPSRSQILRTPSLGRDGAHDKGSGRAAVSDELRQWYQRSTASHKEHSRLSHTSSTSSDSGSQYSTSSQSTFVAHSRVTRMPQMCKATSAALPQSQRSSTPSSEIGATPPSSPHHILTWQTGEATENSPIMDGSESPTHQSTDE------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AR03-1", "uniprot_id": "A0A8I6AR03_RAT", "id": "A0A8I6AR03-1", "name": "", "aln": "MAAGLLGSEDVPCSWDLACRVLRTCREGNLHLLQLMLKPWCIPRAVYQMTEGRRCQVHLLDDRKLELLVQPKLLAKELLDLVASHFNLKEKEYFGIAFTDETGHLNWLQLDRRVLEHDFPKKSGPVVLFFCVRFYIESISYLKDNATIELFFLNAKSCIYKELIDVDSEVVFELASYILQEAKGDFSSNEVVRSDLKKLPALPTQALKEHPSLAYCEDRVIEYYKKLNGQTRGQAIVNYMSIVESLPTYGVHYYAVKDKQGIPWWLGLSYKGIFQYDYHDKVKPRKIFQWRQLENLYFREKKFSVEVHDPR-RASVTRRTFGHSGIAVHTWYACPALIKSIWAMAISQHQFYLDRKQSKSKIHAARSLSEIAIDLTETGTLKTSKLANMGSKGKIISGSSGSLLSSGSQESDSSQSAKKDMLAALKSRQEALEETLRQRLEELKRLCLREAELTGKLPVEYPLDPGEEPPTVRRRIGTAFKLDEQKILPKGEEAELERLEREFAIQSQITEAARRLASDPNVS-KKLKKQRKTSYLNALKKLQEIENAINENRIKSGKKPTQRASLVIDDGNIASEDSSLSDALVLEDEDSQVT--STISPLQSPHKGLPPRPPSTHNRPPPPQSLEGLRQMHYHRTDYDKSPLKPKMWSESSLDEPYEKVKKRSSHGHSSSHKRFPSTGSCTEAG-VSSSLQNSPIRSLPHWNSQSSMPSTPDLRVRSPHYVHSTRSVDISPTRLHSLALHFRHRSSSLESQGKLLGSENDTGS---PDFYT--PRTRSSNGSDPMDDCSSCTSHSSSEHYYP-AQMNANYSTLAEDSPSKARQRQRQRQRAAGALGSASSGSMPNLAARSGAASAG-----GGVYLHSQSQPSSQYRIKEYPLYIEG-SATPVVVRSLESDQEGHYSVKAQFKTSNSYTAGGLFKESWRGGG-----DEGDAGRLTPSRSQILRTPSLGRDGAHDKGSGRAAVSDELRLWYQRSTASHKEHSRLSHTSSTSSDSGSQYSTSSQSTFVAHSRVTRMPQMCKATSAALPQSQRSSTPSSEIGATPPSSPHHILTWQTGSYG-DSCFLDSSLYPELADVQWYGQEKAKPGTLV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M3AJF7-1", "uniprot_id": "A0A8M3AJF7_DANRE", "id": "A0A8M3AJF7-1", "name": "", "aln": "MEAVLLSLGESVCVRHSALWDVTSAALRRLRHAHFR-APEVLVRAVYQMTEGRRCQVHLLDDRKLELLVQPKLMAKDLLDLVASHFNLKEKEYFGISYVDETGHFSWLQLDRRVLEHEFPKKSGPVVLYFCVRFYIESISYLKDNATIELFFLNAKSCIYKELIEVDSEVVFELASYILQEAKGDFTSNDVTRADLKKLPALPTQALKEHPSLAYCEDRVIEHYKKLSGQSRGQAIVNYMSIVESLPTYGVHYYAVKDKQGIPWWLGLSYKGIFQYDYQDKVKPRKVFQWRQLENLYFREKKFSVEVHDPRSRASVTRRTFGHSGIAVHTWYACPTLIKSIWAMAISQHQFYLDRKQSKSKIHAARSLNEIAIDLTETGTLKTSKLANMGSKGKIISGSSGSLLSSGSQESDSSQTAKKDMLAALRARQEALEETLRQRIEELKNICIREAELTGKLPKEYPLDPGEEPPTVRRKIGTAFKLDEQKILPKGEEEELERLEREFAIQSQITEAARRLASDPHISSKKLKKQRKTSYLNALKKLQDIENGINEYRVRSGKKPTQRASLIIEEANIGSEDSSLSDALVLDDDDSQVTGTPTFSPAASPHKGLPPRPPS-HSRPPPPQSLDGLRHLHYQRSDYDKSPIKPRMWSESSLDEPYERVKKRSSH--SSSHRRFPSTGSC-EAG-VSNSLQNSPVRSLPHWNSQSSMPSTPDLRTRS--YVHS-----------ASLTQPFRGRSSSLESQGKLLSLEPDTEAGLSPDLFLSGPQRTGSNGSVVPDDCSSCTSHSSSEHYYPSSTSNPNYCTLAEDSPSKARQRQRQRHKSAGHLGASSSGSMPNLAARNGSTHGGVCGSHQGVYLHSQSQPSSQYRIKEYPLYTEGSSPNAVVVRSLENDQEGHYSVKAQFKTSNSYTAGGLYKEGWGSGEDGEAGGGGGSGRLTPSRSQIVRTPSLGREGGG--GGGRAAVSEELRCWYQRSSGSIKEHSRVTHTSSNSSDG----------------RGGRIGTLVKGSPAASPHSQRSGTPCSDPAATPPCSPQHILNWQSGSPFADITFLSSPLCSELADVQWYGHEKAKPGTLV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *************************:**:*******************::.*****:.***********:**********:***********************************:*********************:**:*.*:****************************:****.**:***********************************************:*******:************************ ***********************:********************************.**********************************************:*********::************:****.:*:********** *********** ***:****************** **************************::* *******************:***.*** *::***********:*::.**.************:*:***** .*:** ************ *.********:***::**:*.******:**:************:******* ****:******** *** *.******:*.*****************.** **** **: ** ************. * ** : **:: *: .**** ***************** : *.**.*****************:::** **::***********.*: * ********************** ** ....*******.***********************:**.* .* . *.:**********:*******:*. *.******:*** *****:.* *****::****.***. * *: : *.:.** *:****.**.*: .****.**:***.**:*. : ::... . ..: ", "identical_positions": 811, "similar_positions": 122, "identity": "73.59%" }, { "cls_id": "homologset.agr.RGD:1309051", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q68FW6-1", "uniprot_id": "PPR36_RAT", "id": "Q68FW6-1", "name": "Protein phosphatase 1 regulatory subunit 36", "aln": "MYKGETLFSIPELYPRRKQFVGQSSTRLDQCGLRLGMWYWKDETKSLEFR----------------SFTPAVELKEKGKKGKAVHFAEMDGTASERLTDKRFVPRDEKSAKTLEKRGQQGNVTLDDVKFVALLSLQDTEMQRVCSFTTFMRNKSLDSFLMALLYYLSYYLERLSMEKKPQSYMVGLVEKKEIELVMSKLEDAQKYLAQK-------YCKLVLGVGMADKHHMNCGKDKISDTQKDWKFFESFYTFCTCIAWIVFRRQYLKEIEEEVGRLFRTNMFNIPRRKREDEESGGEKKRMTLVQFRRMMAKRPAIKKAMDMRSPVLSTLLPSLREKAQHIAEKKY-VAGIKLQPRVEKDITNLESVVMPVVGILGEPRNLFN---------------------------PHTLLPLESEENGKTS----------------------------GRNSSIVERNNTSIQNTLNLVMSKLTSQNSFPK----------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3Z0R2-1", "uniprot_id": "PPR36_MOUSE", "id": "D3Z0R2-1", "name": "Protein phosphatase 1 regulatory subunit 36", "aln": "MVKSEAMFTVPEFYSRRKQFVGQSSTRLDQCGLRLGMWYWKDETKTLEFK----------------SFTPAIELKEKGKKGKAVHFAEMDSGASERLTDKRFASRDEKAAKALEKRSQQGNVTLDDVKFVALLSLQDTEMQRICSFTTFLRNKNLDSFLMALLYYLSYYLQRLSMEKNPQSRVVGLIEKKEVELVVNKLEDAQKYLAQK-------YCILVLGLGMADKHHLSCGKEKISDTQKDWKFFESFYTFCTCIAWIVFRRQYLTEIEEEVGRLFRTNMFNIPRRKHEDEASGGEKKRMTLVQFRRMMAKRPAIKKAVDMRSPVLSTLLPSLREKAQHITEKKY-VAGIKLQPREENIITDLESVAMPIVGILGEPRNLFN---------------------------PNTLLPLELEENTKPS----------------------------GRSSSIVETNNTKIQNTLSLVMSKLASPSTCPK----------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96LQ0-1", "uniprot_id": "PPR36_HUMAN", "id": "Q96LQ0-1", "name": "Protein phosphatase 1 regulatory subunit 36", "aln": "------MYRVPEFYARRKRLGGQTPYLMDQLGLRLGMWYWKDETRTLEFRRFAAEDSVQWLLKHHPHFTPAAEVKEKGKKGKAVHFAETDGPASDRLTDKRLAAKDDKSAKAVEKRGQQGTITLDDVKFVTLLLLQDTEMQRICSFTTFMRNKNLDNFLMALLYYLSHYLEKNSLEKKPKSYMVGLVEKKEMELVLSELEAAQRYLAQK-------YCILVLGLAVPDKHHMCCGKEKISDTQKDWKFFESFYTFCTYVAWIVFRRQHLTEIEEEVGRLFRTNMFNIPRRRREDEESGGEKKRMTFVQFRRMMAKRPAIKKAINMRSPVMSTLLPSLREKAQNVFEKKYHQVDVRFPAEMQKHVGTLDSVPMPVVGILGEPRCLFN---------------------------PHTLHPLDPEENTKSF----------------------------GRYPSLMENNNMRIQDTLDLVMKTLSSHTSCPK----------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VGY1-1", "uniprot_id": "Q9VGY1_DROME", "id": "Q9VGY1-1", "name": "Protein phosphatase 1 regulatory subunit 36", "aln": "MKRVHVDNYTPKYYS--------------------GKWSWSAEKDCLEFE----------------PHNDLENARERYITTNGYKFLRIIDQEEELIFRQAYVRD--------TGTYDFDTLVINDIRDLVLFLMPSDFLT--YRFVEFMHRPAVHRLIHALIIYFEYFLRMVEFVLVRRDELAD---QIQSDQTIDMKKTFSIYLSQYRLLVARNYSVILKGEGDMAKYYHMKEIINISDTSRDRVFHEQFLAVMTQIVWICMHRRAYNVIEMEMNRLFRSDHFVMARP--EYLSFTPAERSLLYGRNHKIVNYRTQISPLVQELEHVAEEDMPILWIGERKYRGNDKRIAEMELEYIVPGPQLRMIDVAH---GILGHPKDLYNTILDLDWPTVRYSNFSLGYDPYHIIRQPHLDIPKIDALKARKMNENYEHFYKVYRIYEPHSVQILQKWLKRDKLVQFYRSGGLLLTNVVSRCEKELAEKVPVTKVDQVISNYFKVKSRLRKGSPYEPDNVSITSSRIGG-FNSPRQKKTPQEYYFD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8INL4-1", "uniprot_id": "Q8INL4_DROME", "id": "Q8INL4-1", "name": "Protein phosphatase 1 regulatory subunit 36", "aln": "MKRIHVDNYAPKYYS--------------------GKWSWDSEKDCLHFQ----------------AHNDLENARERYIMTNGYRFLRTIDQEEELIFRQEYVLP--------KSNYS-DVVVVGDIRNLVLYLMPSEFLT--YKFVEFMYERDTHLLLHSLIIYFEHYLRLVEFILIRRDELSGPLGQVQSEQTNDMKRTFSVYLSQYRMLVARNYCRIIGGEDNMSKYYHMKPISNISATIHDKFFHEHFLAVAIQIVWICMHRRAYYVIEMEINRLFRSEHFVSAHP--EYLEFTEAERSLLYGRNKKNYNYRIQESPLVQELKLVPEEDLPILWIGERKYRGNDIRIAEIELEYIVPGSQLSFIDVSH---GIMGHPKSLYNTLLSLDWPAVRFSNFSEKFDPYHIIRRPHLQIPKIGELQMRTMKEKYEHFYKLCKVHERVTHHQICKWVKRDINIAFFRSGG-LLTNVVSRCEKELASTSSGQRVDQIISNYFKIMSKIRK-EDRDPEHASSTRSSIASRFSVGKAKR--------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: *. * * *. *. *.*. .. : :*: :. :* . . .: : : . . . :.:.*:: :.* : . : *. *: . . :: :*: *:.::*. .: :. : . : : : . . . . **:* *. :: * *:: :** * :* *.* * :. :.** ::*: ** *:.****:: * .: * :: : : :: * . :: . * . :* * :: :. . :.: : .* **:*.*: *:* *: * : : . : . .. : :.:. . *:. . : ", "identical_positions": 56, "similar_positions": 126, "identity": "10.33%" }, { "cls_id": "homologset.agr.RGD:1309052", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q92784-1", "uniprot_id": "DPF3_HUMAN", "id": "Q92784-1", "name": "Zinc finger protein DPF3", "aln": "MATVIHNPLKALGDQFYKEAIEHCRSYNSRLCAERSVRLPFLDSQTGVAQNNCYIWMEKRHRGPGLAPGQLYTYPARCWRKKRRLHPPEDPKLRLLEIKPEVELPLKKDGFTSESTTLEALLRGEGVEKKVD--AREEESIQEIQRVLENDENVEEGNEEEDLEEDIPKRKNRTRGRARGSAGGRRRHDAASQEDHDKPYVCD--------------ICGKRYKNRPGLSYHYAHTHLASEEGDEAQDQETRSPPNHRNENHRPQKGPDGTVIPNNYCDFCLGGSNMNKKSGRPEELVSCADCGRSGHPTCLQFTLNMTEAVKTYKWQCIECKSCILCGTSENDDQLLFCDDCDRGYHMYCLNPPVAEPPEGSWSCHLCWELLKEKASAFGCQA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6AL27-1", "uniprot_id": "A0A8I6AL27_RAT", "id": "A0A8I6AL27-1", "name": "", "aln": "MATVIHNPLKALGDQFYKEAIEHCRSYNSRLCAERSVRLPFLDSQTGVAQNNCYIWMEKRHRGPGLAPGQLYTYPARCWRKKRRLHPPEDPKLRLLEIKPEVELPLKKDGFTSESTTLEALLRGEGVEKKVD--AREEESIQEIQRVLENDENVEEGNEEEDLEEDIPKRKNRTRGRARGSAGGRRRHDAASQEDHDKPYVCD--------------ICGKRYKNRPGLSYHYAHTHLASEEGDEAQDQETRSPPNHRNENHRPQKGPDGTVIPNNYCDFCLGGSNMNKKSGRPEELVSCADCGRSGHPTCLQFTLNMTEAVKTYKWQCIECKSCILCGTSENDDQLLFCDDCDRGYHMYCLNPPVAEPPEGSWSCHLCWELLKEKASAFGCQA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P58269-1", "uniprot_id": "DPF3_MOUSE", "id": "P58269-1", "name": "Zinc finger protein DPF3", "aln": "MATVIHNPLKALGDQFYKEAIEHCRSYNSRLCAERSVRLPFLDSQTGVAQNNCYIWMEKRHRGPGLAPGQLYTYPARCWRKKRRLHPPEDPKLRLLEIKPEVELPLKKDGFTSESTTLEALLRGEGVEKKVD--AREEESIQEIQRVLENDENVEEGNEEEDLEEDVPKRKNRTRGRARGSAGGRRRHDAASQEDHDKPYVCD--------------ICGKRYKNRPGLSYHYAHTHLASEEGDEAQDQETRSPPNHRNENHRPQKGPDGTVIPNNYCDFCLGGSNMNKKSGRPEELVSCADCGRSGHPTCLQFTLNMTEAVKTYKWQCIECKSCILCGTSENDDQLLFCDDCDRGYHMYCLNPPVAEPPEGSWSCHLCWELLKEKASAFGCQA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A9LMC0-1", "uniprot_id": "DPF3_DANRE", "id": "A9LMC0-1", "name": "Zinc finger protein DPF3", "aln": "MATVIQNPLKALGDQFYREAIEHCRSYNARLCAERSVRMPFLDSQTGVAQNNCYIWMEKRHRGPGMAAGQMYTYPARCWRKKRRLHTPLDPQLRLCELRLEAELMAKREAPQTEATALEALLRGDGILDKRNNNAKEEETLLEIQRVLEADENGDGFHDDEDFEVDTPKRKHRNKGRGRGS--GRRRTEAVANDDQDKPYVCDNRYKQKHNSKTADSVCGKRYKNRPGLSYHYAHTHLAEEEGEEERETEIPQSPPVHHENHKPQKAPDGSIIPNDYCDFCLGDSGSNRKTGQAEELVSCSDCGRSGHPSCLQFTDNMMQAVRTYQWQCIECKSCSLCGTSENDDQLLFCDDCDRGYHMYCLKPPMTQPPEGSWSCHLCQNLLKDKASGVEDP-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****:***********:**********:*********:**************************:*.**:***************.* **:*** *:: *.** *::. :*:*:*******:*: .* : *:***:: ******* *** : :::**:* * ****:*.:**.*** **** :*.:::*:******* :*********************.***:* :: * ..* ::***:***.***::***:*******.*. *:*:*:.******:********:***** ** :**:**:********* **************************:**:::*********** :***:***.. ", "identical_positions": 271, "similar_positions": 73, "identity": "68.78%" }, { "cls_id": "homologset.agr.RGD:1309053", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4A0E8-1", "uniprot_id": "D4A0E8_RAT", "id": "D4A0E8-1", "name": "Protein arginine N-methyltransferase 5", "aln": "-MAAMAVGGAGGSRVSSGRDLNCVPEIADTLGAVAKQGFDFLCMPVFHPRFKREF--IQEPAKNRPGPQTRSDLLLSGRDWNTLIVGKLSPWIHPDSKVEKIRRNSEAAMLQELNFGAYLG-LPAFLLPLNQEDNTNLARVLTNHIHTGHHSSMFWMRVP--LVAPEDLRDDVIENAPTAHTEEYSGEEKTWLWWHNFRTLCDYSKRIAVALEIG-ADLPSSHVIDRWLGEPIKAAILPTSIFLTNKKGFPVLSKMQQRLIFRLLKLEVQFIITG---------------TNHHSEKEFCSYLQYLEYLSQNRPPPNAYELFAKGYEDYLQSPLQPLMDNLESQTYEVFEKDPIKYSQYQQAIYKCLLDRVPEEEKETNVQVLMVLGAGRGPLVNASLR--AAKQAERRIRLYAVEKNPNAVVTLENWQFEEWG-SQVTVVSSDMREWVAPE------KADIIVSELLGSFADNELSPECLDGAQHFLKD-DGVSIPGEYTSFLAPISSSKLYNEVRACREKDRDPEAQFEMPYVVR---LHNFHQLSAPQPCFTFSHPNRDPMIDNNRYCTLEFPVEVNTVLHGFAGYFETVLYRDITLSIRP--------------------------ETHSPGMFSWFPIFFPIK-PITVHEGQNICVRFWRCS--NSKKVWYEWAVT----------------------------------------------------------------------------------------------------------------------------------APVCSSIHNPTGRSYTIGL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CIG8-1", "uniprot_id": "ANM5_MOUSE", "id": "Q8CIG8-1", "name": "Protein arginine N-methyltransferase 5", "aln": "-MAAMAVGGAGGSRVSSGRDLNCVPEIADTLGAVAKQGFDFLCMPVFHPRFKREF--IQEPAKNRPGPQTRSDLLLSGRDWNTLIVGKLSPWIHPDSKVEKIRRNSEAAMLQELNFGAYLG-LPAFLLPLNQEDNTNLARVLTNHIHTGHHSSMFWMRVP--LVAPEDLRDDVIANAPTTHTEEYSGEEKTWMWWHNFRTLCDYSKRIAVALEIG-ADLPSNHVIDRWLGEPIKAAILPTSIFLTNKKGFPVLSKVQQRLIFRLLKLEVQFIITG---------------TNHHSEKEFCSYLQYLEYLSQNRPPPNAYELFAKGYEDYLQSPLQPLMDNLESQTYEVFEKDPIKYSQYQQAIYKCLLDRVPEEEKETNVQVLMVLGAGRGPLVNASLR--AAKQAERRIRLYAVEKNPNAVVTLENWQFEEWG-SQVTVVSSDMREWVAPE------KADIIVSELLGSFADNELSPECLDGAQHFLKD-DGVSIPGEYTSFLAPISSSKLYNEVRACREKDRDPEAQFEMPYVVR---LHNFHQLSAPKPCFTFSHPNRDPMIDNNRYCTLEFPVEVNTVLHGFAGYFETVLYRDITLSIRP--------------------------ETHSPGMFSWFPIFFPIKQPITVHEGQNICVRFWRCS--NSKKVWYEWAVT----------------------------------------------------------------------------------------------------------------------------------APVCSSIHNPTGRSYTIGL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14744-1", "uniprot_id": "ANM5_HUMAN", "id": "O14744-1", "name": "Protein arginine N-methyltransferase 5", "aln": "-MAAMAVGGAGGSRVSSGRDLNCVPEIADTLGAVAKQGFDFLCMPVFHPRFKREF--IQEPAKNRPGPQTRSDLLLSGRDWNTLIVGKLSPWIRPDSKVEKIRRNSEAAMLQELNFGAYLG-LPAFLLPLNQEDNTNLARVLTNHIHTGHHSSMFWMRVP--LVAPEDLRDDIIENAPTTHTEEYSGEEKTWMWWHNFRTLCDYSKRIAVALEIG-ADLPSNHVIDRWLGEPIKAAILPTSIFLTNKKGFPVLSKMHQRLIFRLLKLEVQFIITG---------------TNHHSEKEFCSYLQYLEYLSQNRPPPNAYELFAKGYEDYLQSPLQPLMDNLESQTYEVFEKDPIKYSQYQQAIYKCLLDRVPEEEKDTNVQVLMVLGAGRGPLVNASLR--AAKQADRRIKLYAVEKNPNAVVTLENWQFEEWG-SQVTVVSSDMREWVAPE------KADIIVSELLGSFADNELSPECLDGAQHFLKD-DGVSIPGEYTSFLAPISSSKLYNEVRACREKDRDPEAQFEMPYVVR---LHNFHQLSAPQPCFTFSHPNRDPMIDNNRYCTLEFPVEVNTVLHGFAGYFETVLYQDITLSIRP--------------------------ETHSPGMFSWFPILFPIKQPITVREGQTICVRFWRCS--NSKKVWYEWAVT----------------------------------------------------------------------------------------------------------------------------------APVCSAIHNPTGRSYTIGL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9U6Y9-1", "uniprot_id": "ANM5_DROME", "id": "Q9U6Y9-1", "name": "Protein arginine N-methyltransferase 5", "aln": "-MNYYVCLHQEG--------VNSIPKLIEK--AFANN-YNVVSTSINANMLP------FEPHESDP---TYPATILSGSDWNSKVIFTMS-DVNVDSPNDKLREHAKEVFMRDVAWAEHLQNVGNLMVRLRGPENENLASIVLAKTKDDFPSGNWFIQVP--ITNPELATFEHRKDATAEEVAEAESND-PWNWWNNLRMVTKHSTKVKVVIELNDADRPSKETVRRWLGEPIEAIIIPSSLFVRNRSNYCVLKKEWQLIVGHFISVRANIIIS-----------------TNPNDKALCQYADYVNKLIND----NCDKHMLNSYENMLEIPLQPLCDNLDTYTYEVFETDPVKYKLYQDAVQAALLDRVSAAEAKTKLTVVMLLGGGRGPLARAVFN--AAELTKRKVRLYIIEKNPNAIRTLSNMVKTLWADKDVHIFSKDMRDFSPPE------LADIMVSELLGSFGDNELSPECLDGALKLLKP-DGISIPYKSTSYINPLMSAVLHQNV--CQLLPTYP--AFDYGYVSL---LKNIYHIDEPQALFEFVHPNRAENIDNTRCKTVSFKVNKDCVLHGIGGYFDTHLYKDICLSINP--------------------------LTHTPGMFSWFPMFFATR-PRTLREGQTISIQFWRCV--DATKVWYEWQVVN---------------------------------------------------------------------------------------------------------------------------------SPDDWEHHNTRGTGYNMRL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38274-1", "uniprot_id": "HSL7_YEAST", "id": "P38274-1", "name": "Protein arginine N-methyltransferase HSL7", "aln": "MHSNVFVGVKPGFNHKQHSKKSRFLENVSSHSPELPSNYDYVLLPITTPRYKEIVGQVFKDFQRQSIQNWKPLQIPEPQLQDICIPPFNVKKLDNDDTPSYIGLLSSWLELESRDPNVRDLGLKVLLNECKYARFVGINKLILAPPRDLSNLQLYGQMIYRLLQNRIVFAAPALTISISLPLYEDSDPLATWELWNTVRKQCEYHPSLTISLALP-RTRTPSYVLNRWLAEPVSCLLVSSSIFASNQYDYPVLHKFNQNLILKFQKVNGDSQILGNELCVILHGMEKYANNVKGGESAYLEYINYLLKKGDKVLNSNSNHQFLLQEDSRIMPPLKPHSDNLLNSTYLTFEKDLVKYDLYESAILEALQDLAPRASAKR-PLVILVAGAGRGPLVDRTFKIISMLFMDSKVSIIAIEKNPQAYLYLQKRNFDCWD-NRVKLIKEDMTKWQINEPSEKRIQIDLCISELLGSFGCNELSPECLWSIEKYHSHNDTIFIPRSYSSYIAPISSPLFYQKLSQTNRSLEAPWIVHRVPYCILSSRVNEVWRFEHPMAQKDTVQDEDDFTVEFSQSSLNEFKIKHRGEIHGFIGFFSANLYNNIFLSTLPNDSTVRLKFSEETLMNTRREENLIKKCDHTPNMTSWSPIIFPLKQPISFIDDSELSVLMSRIHSDTEQKVWYEWSLESFIYLMLSNYTSAVTAASMTIPRSIVTDDTKTLAHNRHYSATTNQKLDNQIDLDQDIENEEEQGFLSNLETGWQSVQDIHGLSETAKPDHLDSINKPMFDLKSTKALEPSNELPRHEDLEEDVPEVHVRVKTSVSTLHNVCGRAFSLPL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . . : .. . . :: : .: : : . . : . : : : *. . : :. :.. : :: . .: :: : : : : : : * .. .* *:..* .: : : : : ... .: ***.**:.. ::.:*:* *: .: ** * * :: :: .:. : * : .:. .* :*: :. *. . : :. : **:* *** . ** .**.* :**. *:.*: .* * .. . . *::: *.*****. :. : . :: : :****:* *.: * . * :...** .: * *: :*******. ******** . : . * : ** . :*:: *: *. ::::: . * . * :::. ::. * . : : :: .: .* :: :**: *:*.: **.:* ** * *:*.* ** *::*. : * :. :.. :.: : * ****** : . ** * .:.: *", "identical_positions": 112, "similar_positions": 197, "identity": "13.49%" }, { "cls_id": "homologset.agr.RGD:1309054", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6ASZ5-1", "uniprot_id": "TCF25_RAT", "id": "A0A8I6ASZ5-1", "name": "Ribosome quality control complex subunit TCF25", "aln": "MSRRALRRLRGEQRGQEPLGPDALQFVLLDDDDAEEEGPKTG------LGGRRPGGAGKEGVRVNNRFELINIEDLEDDLVVNGERSDCTLPDSASSGNK--GRAKHGNPENKQDGDAAAKAGSSEQSNASGKLRKKKKKQKNKKSCTGESSENGLEDIDRILER----------IEDSSGFSHPGPPPLSSRKHVLYVEHRHLNPDTELKRYFG-------------------ARAVLGEQRPRQRQR---------------VYPKCTWLTTPKSTWPRYSKPGLSMRLLES--------------------------KKGLSFFAFE--HSEEYQQAQHKFLVAVESMEPNNIVALLQTS--PYHVDSLLQLSDACRFQEDQEMARDLIG------EPAYPHLLPMEKSWC----RRP-HWSFYLALYKQMSFLEKRGCPRTALEYCKLILSLEPDEDPLCMLLLIDHMALRARNYEYLIRLFQEWEAHRNLSQLPNFAFSVPLAYFLLSQQTDLPDHELSSARQQASLLIQQALTMFPGVLMPLLEYCSVRPDATVSNHRFFGPDAEISQPPALSQLVSLYLGRSHFLWKEPAIMSWLEENVHEVLEAVDSGDPAVEACENRRK---------VLYQRAPRNIHRHVILSEIKEAVAALPSDVTTQS-VMGFDPLPPVDTIYSYVRPERLSPVSHGNTIALFFRSLLPNYTTEGERLEEGVAGGPNRNQGLNRLMLAVRDMMANFHFNDLEVPREDNPEGEGDWD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R3L2-1", "uniprot_id": "TCF25_MOUSE", "id": "Q8R3L2-1", "name": "Ribosome quality control complex subunit TCF25", "aln": "MSRRALRRLRGEQRGQEPLGPDALKFVLLDDDDAEEEGPKPG------LGGRRPGGAGKEGVRVNNRFELINTEDLEDDLVVNGERSDCTLPDSVSSGNK--GRAKHGNAETKQDG-GATKAGSSEQSNASGKLRKKKKKQKNKKSCTGESSENGLEDIDRILER----------IEDSSGFSHPGPPPLSSRKHVLYVEHRHLNPDTELKRYFG-------------------ARAVLGEQRPRQRQR---------------VYPKCTWLTTPKSTWPRYSKPGLSMRLLES--------------------------KKGLSFFAFD--HNEEYQQAQHKFLVAVESMEPNNIVVLLQTS--PYHVDSLLQLSDACRFQEDQEMARDLIERALYSMECAFHPLFSLTSGTCRLDYRRPENRSFYLTLYKQMSFLEKRGCPRTALEYCKLILSLEPDEDPLCMLLLIDHLALRARNYEYLIRLFQEWEAHRNLSQLPNFAFSVPLAYFLLSQQTDLPEHELSSARQQASLLIQQALTMFPGVLMPLLEYCSVRPDATVSNHRFFGPDAEISQPPALGQLVSLYLGRSHFLWKEPAIMSWLEENVHEVLQAVDAGDPAVEACENRRK---------VLYQRAPRNIHRHVILSEIKEAVAALPSDVTTQS-VMGFDPLPPLDTIYSYVRPERLSPVSHGNTIALFFRSLLPNYTTEGERLEEGVAGGPNRNQGLNRLMLAVRDMMANFHFNDLEVPREDNPEGEGDWD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BQ70-1", "uniprot_id": "TCF25_HUMAN", "id": "Q9BQ70-1", "name": "Ribosome quality control complex subunit TCF25", "aln": "MSRRALRRLRGEQRGQEPLGPGALHFDLRDDDDAEEEGPKRE------LGVRRPGGAGKEGVRVNNRFELINIDDLEDDPVVNGERSGCALTDAVAPGNK--GRGQRGNTESKTDG-DDTETVPSEQSHASGKLRKKKKKQKNKKSSTGEASENGLEDIDRILER----------IEDSTGLNRPGPAPLSSRKHVLYVEHRHLNPDTELKRYFG-------------------ARAILGEQRPRQRQR---------------VYPKCTWLTTPKSTWPRYSKPGLSMRLLES--------------------------KKGLSFFAFE--HSEEYQQAQHKFLVAVESMEPNNIVVLLQTS--PYHVDSLLQLSDACRFQEDQEMARDLVERALYSMECAFHPLFSLTSGACRLDYRRPENRSFYLALYKQMSFLEKRGCPRTALEYCKLILSLEPDEDPLCMLLLIDHLALRARNYEYLIRLFQEWEAHRNLSQLPNFAFSVPLAYFLLSQQTDLPECEQSSARQKASLLIQQALTMFPGVLLPLLESCSVRPDASVSSHRFFGPNAEISQPPALSQLVNLYLGRSHFLWKEPATMSWLEENVHEVLQAVDAGDPAVEACENRRK---------VLYQRAPRNIHRHVILSEIKEAVAALPPDVTTQS-VMGFDPLPPSDTIYSYVRPERLSPISHGNTIALFFRSLLPNYTMEGERPEEGVAGGLNRNQGLNRLMLAVRDMMANFHLNDLEAPHEDDAEGEGEWD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q05468-1", "uniprot_id": "RQC1_YEAST", "id": "Q05468-1", "name": "Ribosome quality control complex subunit 1", "aln": "MSSRALRRLQDDNALLESLLSNSNANKMTSGKSTAGNIQKRENIFSMMNNVRDSDNSTDEGQMSEQDEEAAAAGERDTQSNGQPKRITLASKSSRRKKNKKAKRKQKNHTAEAAKDKGSDDDDDDEEFDKIIQQFKKTDILKYGKTKNDDTNEEGFFTASEPEEASSQPWKSFLSLESDPGFTKFPISCLRHSCKFFQNDFKKLDPHTEFKLLFDDISPESLEDIDSMTSTPVSPQQLKQIQRLKRLIRNWGGKDHRLAPNGPGMHPQHLKFTKIRDDWIPTQRGELSMKLLSSDDLLDWQLWERPLDWKDVIQNDVSQWQKFISFYKFEPLNSDLSKKSMMDFYLSVIVHPDHEALINLISSKFPYHVPGLLQVALIFIRQGDRSNTNGLLQRALFVFDRALKANIIFDSLNCQLPYIYFFNRQFYLAIFRYIQSLAQRGVIGTASEWTKVLWSLSPLEDPLGCRYFLDHYFLLNNDYQYIIELSNSPLMN-CYKQWNTLGFSLAVVLSFLRIN------EMSSARN----ALLKAFKHHP------LQLSELFKEKLLGDHALT-KDLSIDGHSAENLELKAYMARFPLLWNRNEEVTFLHDEMSSILQDYHRGNVTIDSNDGQDHNNINNLQSPFFIAGIPINLLRFAILSEESSVMAAIPSFIWSDNEVYEFDVLPP--------MPTSKESIEVVENIKTFIN-------------EKDLAVLQAERMQDEDLLNQIRQISLQQYIHENEESNENEG-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** ******:.:: *.* ..: : ....: : * . * ...: .** :: * : : : : :* : .: ** * ::.:. .. . .*: . : **.. * *: ..::.*:*: .. * :*...*:.: . * :.: :.::*:*.**:* *. .: : ** :: * ::*: :*. :. * .: ***:**.* :* :**: *: :.: ::: .* ::* :: : * :* **** .***:: * *:. :..*: : * : : . * : .***:::: :. * :** ** *: *:: **.* **** ::** * .:*:*:*.* :. : .* .:.**:.:. :* : * ****: : :*:. .* *: ..: : :..* : : .*. .* . :. *:.* :**:. :::*.::: .:*: . *: :::: :.: : .: * *: *..**** ...:**:*. : ::. * ** *** * ..:. :.* *:. *:.:* .. : *: :*:: : :::: * ..*:: ", "identical_positions": 139, "similar_positions": 242, "identity": "18.08%" }, { "cls_id": "homologset.agr.RGD:1309055", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5BKC9-1", "uniprot_id": "NGEF_RAT", "id": "Q5BKC9-1", "name": "Ephexin-1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------METKNSEDQGKPQRKSVSSLWKSKHG------------------------PAEMRPELPP------ETAKETQNE-----------------------------EPRCLIPIQRNSLFNRAMR--HKHKARSMS------------------ERRANDQAGDLPETRKSVNEPLAFNLPQGRLP-------------------------------------------------------------PWRTPAQRGPGAQEASES-------------------------------------------------------------SSTPGNGTTPEECPALTDSPTTLTEALQMIHPIPADSWRNLIEQ--------------------------------------------------------------IGLLYQEYRDKSTLQEIETRRQQDAEIQGNSDGSQAGE----------------------------------DNAEEEEEEEE----EPASPPERRALPQICLLSNPHSRFN--LWQDLPEIQSSGVLDILQPEETKLQEAMFELVTSEASYYKSLNLLVSHFMENERLKK--ILHPSEAHILFSNVLDVMAVSERFLLELEHRMEENIVISDVCDIVYRYAADHFSVYITYVSNQTYQERTYKQLLQEK--TAFRELIAQLELDPKCKGLPLSSFLILPFQRITRLKLLVQNILKRVEEGSEREGTALDAHKELEMVVK-ACNEGVRKMSRTEQMISIQKKMEFKIKS----------VPIISHSRWLLKQGELQQMS--GPKTSRTLRTKKLFREIYLFLFNDLLVICRQIPGDKYQVFDSAPRGLLRVEELEDQ---------GQTLANVFILRLLENADDREATYMLKASSQSEMKRWMTSLAPNRRTKFVSFTSRLLDCPQVQCVHPYVAQQPDELTLELADILNILEKTEDGWIFGERLHDQERGWFPSSMTEEILNPKIRSQNLKECFRVHKMEDPQRSQNKDRRKLGSRNRQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CHT1-1", "uniprot_id": "NGEF_MOUSE", "id": "Q8CHT1-1", "name": "Ephexin-1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------METKNSEDWGKPQRKSESSSRKSNHG------------------------PAEMRPALPPENREAPETGEETQNE-----------------------------EPRRLIPIQRHSLFNRAVR--HRHKARSTS------------------ERRASDQA-DLPKMGKSVNERSAFNLPQGRLS-------------------------------------------------------------PWRTPAQRDTGAQEASES-------------------------------------------------------------SSTPGNGTTPEECPALTDSPTTLTEALQMIHPIPADSWRNLIEQ--------------------------------------------------------------IGLLYQEYRDKSTLQEIETRRQQDAEIQGNSDGSQVGE----------------------------------DAGEEEEEEEEGEEEELASPPERRALPQICLLSNPHSRFN--LWQDLPEIQSSGVLDILQPEEIRLQEAMFELVTSEASYYKSLNLLVSHFMENERLKK--ILHPSEAHILFSNVLDVMAVSERFLLELEHRMEENIVISDVCDIVYRYAADHFSVYITYVSNQTYQERTYKQLLQEK--AAFRELIAQLELDPKCKGLPFSSFLILPFQRITRLKLLVQNILKRVEERSEREGTALDAHKELEMVVK-ACNEGVRKMSRTEQMISIQKKMEFKIKS----------VPIISHSRWLLKQGELQQMS--GPKTSRTLRTKKLFREIYLFLFNDLLVICRQIPGDKYQVFDSAPRGLLRVEELEDQ---------GQTLANVFILRLLENADDREATYMLKASSQSEMKRWMTSLAPNRRTKFVSFTSRLLDCPQVQCVHPYVAQQPDELTLELADILNILEKTEDGWIFGERLHDQERGWFPSSMTEEILNPKIRSQNLKECFRVHKMEDPQRSQNKDRRKLGSRNRQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N5V2-1", "uniprot_id": "NGEF_HUMAN", "id": "Q8N5V2-1", "name": "Ephexin-1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------METRESEDLEKTRRKSASDQWNTDNE------------------------PAKVKPELLPEKEETSQADQDIQDK-----------------------------EPHCHIPIKRNSIFNRSIRRKSKAKARDNP------------------ERNASCLA-DSQDNGKSVNEPLTLNIPWSRMP-------------------------------------------------------------PCRTAMQTDPGAQEMSES-------------------------------------------------------------SSTPGNGATPEEWPALADSPTTLTEALRMIHPIPADSWRNLIEQ--------------------------------------------------------------IGLLYQEYRDKSTLQEIETRRQQDAEIEDNTNGSPASE----------------------------------DTPEEEEEEEE--EEEPASPPERKTLPQICLLSNPHSRFN--LWQDLPEIRSSGVLEILQPEEIKLQEAMFELVTSEASYYKSLNLLVSHFMENERIRK--ILHPSEAHILFSNVLDVLAVSERFLLELEHRMEENIVISDVCDIVYRYAADHFSVYITYVSNQTYQERTYKQLLQEK--AAFRELIAQLELDPKCRGLPFSSFLILPFQRITRLKLLVQNILKRVEERSERECTALDAHKELEMVVK-ACNEGVRKMSRTEQMISIQKKMEFKIKS----------VPIISHSRWLLKQGELQQMS--GPKTSRTLRTKKLFHEIYLFLFNDLLVICRQIPGDKYQVFDSAPRGLLRVEELEDQ---------GQTLANVFILRLLENADDREATYMLKASSQSEMKRWMTSLAPNRRTKFVSFTSRLLDCPQVQCVHPYVAQQPDELTLELADILNILDKTDDGWIFGERLHDQERGWFPSSMTEEILNPKIRSQNLKECFRVHKMDDPQRSQNKDRRKLGSRNRQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VVC6-1", "uniprot_id": "Q9VVC6_DROME", "id": "Q9VVC6-1", "name": "", "aln": "MAMSPVLDAAAKAAGRDLNGNSNAASATAASTATPTAAAAAAATTPRKTKKTIINWLVNSDSENNNRATCDKAGKDNPNPNQNPNSQANPNQNCSCESRAFRDFRGVQTLRLLWSRRIKSASEDQCHSPVHCHTSSSSLGTLKKLNKSVSCLVNAFNNSRDCATPEKTLAKRAASLHNLQDSQAKHKQLHREKDNFYKYKNAEQAKMQAKLRSSADEAILNASETRAKRDDSGCLPGVKSYNSKALSAADKVAKVAKGEAKTQRRAEEPVGEAEVEVEVEFRAKREHNRLEGLSLSAASAQSGGSSESLQTTTTSSSTPTTHSSVTSSTGRSGGRRKYSFKTHAGKSYHQHHHPSRRTSNMDSSNGGISMVAKLTHQFNEIIQKDAKLLEQVKRNNGVWISRGTHVYKIVEKPTSEGKGLPNADDNRISTVQRNIKKFERLEKPSVPLKSEQLMRKHLELMRGSSLSRGPRIKRNLKLPPGSVGIPELAIVSEELKTPTSEEQAKKPKSVQNESQPNHPEELNQSNDKPSDELDLIMGEEGDEEELRQKQRKHKYASIYEKLRFTFAKGRKSASPSPTKAQIREEVSIDEESIKDSTSEDMVTRKEDFTLDLPKEVIPRAEDLEDSSHALLVSPCFEADAKILDALEAVDLKLKVLNPLNDVTTADGERELLLAANDDFEQRILPNSSFVYQAANKQYSNNQILLNQAVNVTLVNAIEGEQMIMEQKQLMKVRDLELTERDIDQPLKRAEKSPEKDDTLEPESLYEPITPVMDETKTEAQTSSLFKIYTKKSELVEDIYQTVEEASTVEVKPNNWLEGYESIAGSQEACPLTYDGYESFAPEEVVTTPTTPSATGTLGRNTRDELPELPKPKRVLNKSPIPLRPAPPKPQAKESEEDENIYDTIKGCYESMHCKATSSSSSGEATLTTDTISLSSNCYESISHIRRSRVATTQNQGHGSAGSCIQLSSSGSTLTISSDHKTNSLYESSLAAAGCVVYGSASVGCRSSLGSSAGSRDSGKPGDKRSSIAGSSDNSDAWVDISDGEIGQATTDATANEAQFIVVRERFKPHRTRSPDWSKRIRDKRLQQKKAISCIEDDSDHYYETLSPLGNKRHSTQLVRQSQDGNRSGGVRSSHRRSKNHSASAHTLGEHVVISDDYDSFETDSDDHGDGEPDLRQRNYNDSGVDMRNHRLPKPPPPQNQVYEFVRKFKDFISSKKSPKGSQQKLYENTPASTLFYVECSKRTEDVYENTDFGPERIPAPETKGPVHQEQAPVLRAKQKNGKSLRSRLRKSLVGSSFDTKQLSSLAPTRSTFYVEDPEGSLPALPLEPEIHGSGELDSGFSDKNCTPLPETPKFSTVARKAKKEAKANRRRTTIGLRPNDPPPPPPPMTGNKSPLDPERELDAEQTTSWYAECGVFKQATNGAVSPRGDEPVTPTPSGHGGVSSWYAESGLYQTSGISVASSSGSSGVSTGNEAGLGDELSSEPHSLFSNEPLYQMYSAAKLESITRDLEAHGSSDGYEEIGLQAKAKPEPLVKPRPTALQLVEPKNGPSRTLWSEIPEVIHSCILPTLTSRERSLQEAKFEIITSEASYLKSLNLLRRHFMNHNAFLDSSVLSAKDRKALFSYIVPVHECSERLLTELEACWQDNIMLLGLSRCIYEIAERHFHVYVAFCEHQGRMDRTLRRLKESKESLAFQQHLERLEASPSCCGLNLHSFLMLPMQRITRLPLLIDAVFSKESPLNREEYESWKLTLALVQKVVGQCNEAANRWEQAFELERIARQLEFPSHVRALAIAPVGVPRAGAKPRFLVKRGELTHLLWRGEDAKLTFGKRLTKISIYAFLFSDLLLLCKRRGESCFSVFDYCPRSMLTLAAGDSLPQLPTKDLKDQAGKNLILMTLLENCDRKTVELVLSCPSVSDQQRWLQAMRPPEAETPGEKLYESWDCPQVVAKHSYESDEPDVLQLELGDVVNVSRKLPDGWYQGERIRDGAVGWFPGSYTEELNSAHVRARNLKQRHRLLTFTATYLESQKSK---------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: *.* *. * * .:.: :: : * : : ::: .. : .:.. . .:* : . . . * :. . . . : : .:: *:. * * . *. . .:: *. ..* : :: ..*.::*. * * : : *: *. * * : . * :.. * ..: .. : *. .. ..: ** : . * :. * * :*:. . **.::**: * :* * ..* **** **::****** ****** ***::: : . :* ..: : *** :: * ***:* *** ::**:: .:. :*. * ** **::: .:* :** ::* :.* **:: : :** .*.* ** : ***:**:****** **:: ::.: . ...* : . * * ***...: .:: :: * :::** : ::.*:*:*:*** :: * .:. *: .: .** ***.***::*:: . :.*** .**.:* : :. .*: *:::: ****.* : . :*...* *: :**: :: * . . . . ***** . *.* :::** * ***.*::*: * *** ***::* ****.* ***: ..::*::***: .*: .: . ..:*.: ", "identical_positions": 188, "similar_positions": 245, "identity": "9.22%" }, { "cls_id": "homologset.agr.RGD:1309057", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LSF9-1", "uniprot_id": "A0ABK0LSF9_RAT", "id": "A0ABK0LSF9-1", "name": "", "aln": "MVLGELHMQKNEVGPSWYTIYNINSNWIKATKIFKESLREMLQDKGLSESEEAFRAPGPALGETSNSNNTNVPEPALATPGLSGTALSSPPGQGADVAAAAAAAAAAAEQTIENIKVGLHEKELWKKFHEAGTEMIITKAGRRMFPSYKVKVTGMNPKTKYILLIDIVPADDHRYKFCDNKWMVAGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQPRLHIVKADENNAFGSKNTAFCTHVFPETSFISVTSYQNHKITQLKIENNPFAKGFRGSDDSDLRVARLQSKEYPVISKSIMRQRLVSSQ--LSAKPDVSPLHSTHQALQHYQYENGAHMQFAAAEPQDLPLNTFPTQRDSSLFYHCLKRRADSARHLDLPCKRSYLETP-SSVGDDHYFRSPPPYDQQMLSPSYCSEVT-PREACMYSSSGPEIAGVSAVDDLPPPPLSCNMWTSVSPYTSYSVQTMETVPYQPFPTHFTATTMMPRLP-IAAQSAQ-----PPGNAHFSVYNQLSQS-QVRERGPSASFPRERGLPAVCERKPPSPHLNTANEFLYS-QSFSLTRESSLQYHSGMGTV-DNWTDG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70325-1", "uniprot_id": "TBX4_MOUSE", "id": "P70325-1", "name": "T-box transcription factor TBX4", "aln": "----------------------------------------MLQDKGLSESEEAFRAPGPALGEASNTSTTNAPEPALATPGLSGAALSSPPGQGADVAAAAAAAA---EQTIENIKVGLHEKELWKKFHEAGTEMIITKAGRRMFPSYKVKVTGMNPKTKYILLIDIVPADDHRYKFCDNKWMVAGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQPRLHIVKADENNAFGSKNTAFCTHVFPETSFISVTSYQNHKITQLKIENNPFAKGFRGSDDSDLRVARLQSKEYPVISKSIMRQRLVSSQ--LSAKPDVSPLHSAHQALQHYQYENGAHMQFAAAEPQDLPLNTFPTQRDSSLFYHCLKRR-DSARHLDLPCKRSYLETP-SSVGDDHYFRSPPPYDQQMLSPSYCSEVT-PREACMYSSSGPEIAGVSAVDDLPPPPLSCNMWTSVSPYTSYSVQTMETVPYQPFPAHFTATTVMPRLPTIAAQSAQ-----PPGNAHFSVYNQLSQS-QVRERGPSASFPRERGLPGMCERKPPSPHLNTANEFLYS-QSFSLTRESSLQYHSGMGTV-ENWTDG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P57082-1", "uniprot_id": "TBX4_HUMAN", "id": "P57082-1", "name": "T-box transcription factor TBX4", "aln": "----------------------------------------MLQDKGLSESEEAFRAPGPALGEAS---AANAPEPALAAPGLSGAALGSPPGPGADVVAAAAAEQ-----TIENIKVGLHEKELWKKFHEAGTEMIITKAGRRMFPSYKVKVTGMNPKTKYILLIDIVPADDHRYKFCDNKWMVAGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQPRLHIVKADENNAFGSKNTAFCTHVFPETSFISVTSYQNHKITQLKIENNPFAKGFRGSDDSDLRVARLQSKEYPVISKSIMRQRLISPQ--LSATPDVGPLLGTHQALQHYQHENGAHSQLA--EPQDLPLSTFPTQRDSSLFYHCLKRR-DGTRHLDLPCKRSYLEAP-SSVGEDHYFRSPPPYDQQMLSPSYCSEVT-PREACMYSGSGPEIAGVSGVDDLPPPPLSCNMWTSVSPYTSYSVQTMETVPYQPFPTHFTATTMMPRLPTLSAQSSQ-----PPGNAHFSVYNQLSQS-QVRERGPSASFPRERGLPQGCERKPPSPHLNAANEFLYS-QTFSLSRESSLQYHSGMGTV-ENWTDG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32T509-1", "uniprot_id": "A0AB32T509_DANRE", "id": "A0AB32T509-1", "name": "", "aln": "----------------------------------------MLQEKASVVADEGMTVAQ----------SGGRPELASDSSHLG---LPTTPSN----PQNNEPDQ-----SIENIKVVLHDRELWKKFHEAGTEMIITKAGRRMFPSYKVKVTGMNPKTKYILLTDIVPADDHRYKFCDNKWMVAGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQPRLHIVKADENNAFGSKNTAYCTHVFHETAFISVTSYQNHKITQLKIENNPFAKGFRGSDEGDLRVSRLQGKDYPVISKNMVRQRLISSHGHLSGKLSAGVLSSHPQVLSHYQYDSGVPLPNS--DSQEALSNSFTSSREPSLLYHCFKHR-DNPRHLELGCKRPYLDTTSSAVSEEHYFRSPPSYDSPLLSHPYCNEALGSREACMYGGLEGEGGGAVGTDDLPAPSLNCNMWASVQPYPRYGMQTVEAMQYQPFTAHFNSTASAASMVSHHSPSMQRPHPTPPDLVTFTTQRVLPPTPSSASTSPSGSGHHDRAHSSLFHRKAGSPLRSQRDFTGYSTHSPTSTREPAYQYQTGLSSVGPHWTDS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***:*. ::*.: .. . ** * :. *. * :.*. . :****** **::****************************************** ************************************************************************************************:***** **:******************************:.****:***.*:******.::****:*.: **.. ... * . *.*.***::.*. : :.*: .:*.:.*:.**:***:*:* *..***:* ***.**::. *:*.::*******.**. :** .**.*. .******.. * .*. ..****.*.*.****:**.**. *.:**:*:: ****.:**.:*: . : : * * **. . *:. . *. : . . .**.* ::*. . .**. ** . : ** :: : :**.: **::*:.:* :***.", "identical_positions": 316, "similar_positions": 133, "identity": "51.97%" }, { "cls_id": "homologset.agr.RGD:1309058", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AGZ6-1", "uniprot_id": "A0A8I6AGZ6_RAT", "id": "A0A8I6AGZ6-1", "name": "", "aln": "MDPRAGVCQGKWTRPGIANSFALVENLHSICRRREREANVRKIFPPKSSSSDTELEDEPFGEGLVLPRAGKLHEFLSPEEETDSTSDSTGSFHRTIQVPRQRGRWDLLESLFQSDLDSDQNGSEDEENLESFFQGKSRGKLQVQDPPSLRSGSMRRCSSLIRLPSDIPKAQTLPTSDSGPPSQHRSVCSWASSITVPQPFHMTLREARKKAQWLASPASFEQERLQAQKQGQEEAECHRQFRAQPVPAHVYLPLYQEIVERREARRRARIQ----QRKELLLSSVKPFSFLEKKEEQKEDTPQRDLAAVAQTKVPPKKATSRKIPKSILEPALGDKLQESELLRKIRIQMRAMDMLQMSSSPISASSNRA---PRTATRTQEEKLSFLQTEFAFQPRVNPEVPDYEGLYKAFQRRAAERRETRETTRNKPFLLRTANLCHTPRSCDAATAGGGRMRTQKSPQPTATPLPSSRSLSGLASFSVNTLPVHITDATRKRESAVRMSLEKKDKSD-MSIQWLEMHKKNCQAMSKSVTLRAKAMDPHKSLEEVFKAKLKENRNNDRKRAKEYKKELEEMRRRIQTRPYLFEQVTKALARKEAEQRYRDTLRQAGLEEEFVRTKSQSTEAV---------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CB59-1", "uniprot_id": "F161B_MOUSE", "id": "Q8CB59-1", "name": "Protein FAM161B", "aln": "------------------------MTVGRTAGGPECAEWSREIFPPKSSSSDTEPEDEQFGEGLVLPRAGKLHEFLSPEEDTDSTSDSTGSFYRTPQVPKQRGRWDVLESLFQSDPDSDLNDAEDEEDLESFFQDKSRGKPQVQDPPSLRHGSMRRCSSMTSLPSDIPKARILPTSDSGPPSQHRSVCSWASSITVPQPFRMTLREARKKAQWLASPASFEQERLQAQKQGEEEAECHRQFRAQPVPAHVYLPLYQEIMERREARRRAGIR----KRKELLLSSLKPFSFLEKKEQQKEDAPQRDSAAVAQTKVSPKKATSRKIPKSILEPALGDKLQEAELLRKIRIQMRAMDTLRMASSPVSTARNRA---PRTAARTQEEKLSFLQTEFEFQPKVNPVVPDYEGLYKAFQKRAAERRETRETTRNKPFLLRTANLSHTPRSCDAATAGGG----KKSPQPTATPLPRSRSLSGLASFSANTLPVHITDATRKRESAVRMSLEKKDKSD-MSIQWLEVHKKNCQAMSKSVTLRAKAMDPHKSLEEVFKAKLKENRSNDRKRAKEYKKELEEMKKRIQTRPYLFEQVTKALARKEAEERYRDALKQAGLEEEFVRTKSQGTEAV---------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96MY7-1", "uniprot_id": "F161B_HUMAN", "id": "Q96MY7-1", "name": "Protein FAM161B", "aln": "------------------------MTVGRPEGAPGGAEGSRQIFPPES-FADTEAGEELSGDGLVLPRASKLDEFLSPEEEIDSTSDSTGSIYQNLQELKQKGRWCLLESLFQSDPESDENLSEDEEDLESFFQDKDRGMVQVQCPQALRCGSTRRCSSLNNLPSNIPRPQTQPPSGSRPPSQHRSVSSWASSITVPRPFRMTLREARKKAEWLGSPASFEQERQRAQRQGEEEAECHRQFRAQPVPAHVYLPLYQEIMERSEARRQAGIQ----KRKELLLSSLKPFSFLEKEEQLKEAARQRDLAATAEAKISKQKAT-RRIPKSILEPALGDKLQEAELFRKIRIQMRALDMLQMASSPIASSSNRANPQPRTATRTQQEKLGFLHTNFRFQPRVNPVVPDYEGLYKAFQRRAAKRRETQEATRNKPFLLRTANLRHPQRPCDAATTGRR----QDSPQPPATPLPRSRSLSGLASLSANTLPVHITDATRKRESAVRSALEKKNKAD-ESIQWLEIHKKKSQAMSKSVTLRAKAMDPHKSLEEVFKAKLKENRNNDRKRAKEYKKELEEMKQRIQTRPYLFEQVAKDLAKKEAEQWYLDTLKQAGLEEDFVRNKGQGTRAVQEKETKIKDFPRFQETTKLSIRDPEQGLEGSLEQPASPRKVLEELSHQSPENLVSLA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7T6U5-1", "uniprot_id": "A0A8N7T6U5_DANRE", "id": "A0A8N7T6U5-1", "name": "", "aln": "-------------------------------------MDQMTMISPTLDFSRSEEGDN----------AHVSESLLSLIEDRKKTEQSMELHLEALKVKRK-------------------------QQVENLELQHQTGLEKRVLQNSLLTTSTEWMLKTNIVQQSIS-------DHDGPDRKHHSSKMVVRNSTSNRIKAARTTGSRYLGTEIERYRKPLPQDSRKAKEEADLAECQKQFRVAPVPEHISKALYDGLMHEQERLRQEGRE----QRRDFLLTMQKPFMFLKREEKKRERLREEKASANKSVKTQPVHVR-KPIPKSVSDPRFSERLKEQDQQRQMRIHLRAQQTLKAASAPIQEQEASADKQPRSTQKSKSKMLGYLDQELSFRPKINTTVPDFDKLHQAFQQKSMETTERRDVTQCKPFQLRTSTLQPRHRSPENSKNSTD-----------KVTIKRSSSFGGLTSLSMDTLPTYITDAARKRSMAVRRSLELKDLKEQENADWMKQHRIRSQAMSKAVAMRAKAMDPHKSLKEVYQEKLKQHRLADLERIKDYQRELKEMKTRVTVRPYLFEQVSQKNAKNNAERRYRNTLEQAGLDENFVRSKGERKKGSDVDNDSADEDHHSTESETQKSTGSEEDGVTNEEEKEVHVETKEEETC----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VN94-1", "uniprot_id": "Q9VN94_DROME", "id": "Q9VN94-1", "name": "", "aln": "--------------------------------MSSHYLNSCVKVPIDPCNNCPAPVYNRPKLSSLGGKKPTDQAHISQPEAETPAWSSQMGVRSLAKFYDSIPDYRDVKHLHR---------VEFYSTLESLRSTSRELRSQAATAPTVERSASVSSCSVGHGKSKKR------PSKGKKIKKRPLVLDPVPPPAILVIPGQQDRCATRPVVHTPNSSCLSDEYDQCLRDLSRLKSFKEDFAVEVADFKRSLKSFEAEFRRPKSTSSNGTQTQTNKQSQTQNRCQKTANPGQHTAERAKCRREMLRRCFSVNDLQGIALEAHSKPSKLAQPARSNYFPLSKQEEIPKIQIQSPTTSSKRSSSASSAARGR---GRRGRVRKPKPGSSVKDEKPLPPLSIYELPEEPVQRRTPSVSPLHPVSRPNLAATLRAEVSRKKVKELKNNCTYHDPRPQ----------FDWEVRKTPAWKSLSLNESHKALLSIRLATRKAEQAFQ------ERQYELHMEMMRQRVKSAPLLLEGPTFWGPEVG---KLTHTCRTEELRHSCEGSRQRRKKKSEFPVPDADTKLQQLRKVYGSEKSCSRQSQRSKRSERRPQGLTTETPSHDSGDDLCSADRAFL---------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. . : . :* * : .* : . . :*.: : :: : . .. . . :: . : : : : :: . :.:* . . : :: ... : . :: : *. :: : : : . . : *..: :* .: : . . :*:::: *:. * : : . :. : : * :*: :: . . . . : : : .: . : : : .*: . .. * *:** . *.: : : :. : . : :. :: . :. .* .. : : .: . .: :. : *: : :: . .:::. . . ** : .. ", "identical_positions": 23, "similar_positions": 149, "identity": "3.37%" }, { "cls_id": "homologset.agr.RGD:1309059", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q6P2K6-1", "uniprot_id": "P4R3A_MOUSE", "id": "Q6P2K6-1", "name": "Serine/threonine-protein phosphatase 4 regulatory subunit 3A", "aln": "-----------------------MTDTRRRVKVYTLNEDRQWDDRGTGHVSSGYVERLKGMSLLVRAESDGSLLLESKINPNTAYQKQQDTLIVWSEAENYDLALSFQEKAGCDEIWEKICQVQGKDPSVDITQDLVDESEEERFDDMS--SPGLELPSCELSR-----LEEIAELVASSLPSPLRREKLALALENEGYIKKLLELFHVCEDLENIEGLHHLYEIIKGIFLLNRTALFEVMFSEECIMDVIGCLEYDPTLSQPRK-HREFLT-KTAKFKEVIPISDPELKQKIHQTYRVQYIQDMVLPTPSVFEEN-MLSTLHSFIFFNKVEIVGMLQED--EKFLTDLFAQLTDEATDEEK------RQELVNFLKEFCAFSQTLQPQNRDAFFKTLSNMGILPALEVILGMD-DTQVRSAATDIFSYLVEYNPSMVREFVMQEAQQNDD-------------DILLINLIIEHMICDTDPELGGAVQLMGLLRTLVDPENMLATANKTEKTEFLGFFYKHCMHVLTAPLLANTTEDKPSKDDFQTAQLLALVLELLTFCVEHHTYHIKNYIINKDILRRVLVLMASKHAFLALCALRFKRKIIGLKDEFYNRYIMKSFLFEPVVKAFLNNGSRYNLMNSAIIEMFEFIRVEDIKSLTAHVIENYWKALEDVDYVQTFKGLKLRFEQQRERQ-DNPKLDSMRS----ILRN-HRYRRDARTLEDEEEMWFNTDEDDMED--------------------GEAVVSPSDKTKNDDDIMDPIS--------------------------------------------------KFMERKKLKESEEKEVLL-KTNLSGRQSP----------------------SFKLSLSSGTKTNLTSQSSATSLPGSPGSP-----------------------------------GSP--------------------------GSPGSPGSVPKSTSQTAAITTKG-GLVGLVDYPDDDEDDDEDED---KEDTLPVSKKAKFES-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AS21-1", "uniprot_id": "A0A8I6AS21_RAT", "id": "A0A8I6AS21-1", "name": "SMEK homolog 1", "aln": "-----------------------MTDTRRRVKVYTLNEDRQWDDRGTGHVSSGYVERLKGMSLLVRAESDGSLLLESKINPNTAYQKQQDTLIVWSEAENYDLALSFQEKAGCDEIWEKICQVQGKDPSVDITQDLVDESEEERFDDMS--SPGLELPSCELSR-----LEEVAELVASSLPSPLRREKLALALENEGYIKKLLELFHVCEDLENIEGLHHLYEIIKGIFLLNRTALFEVMFSEECIMDVIGCLEYDPTLSQPRK-HREFLT-KTAKFKEVIPISDPELKQKIHQTYRVQYIQDMVLPTPSVFEEN-MLSTLHSFIFFNKVEIVGMLQED--EKFLTDLFAQLTDEATDEEK------RQELVNFLKEFCAFSQTLQPQNRDAFFKTLSNMGILPALEVILGMD-DTQVRSAATDIFSYLVEYNPSMVREFVMQEAQQNDDVSKKLTEQKITSKDILLINLIIEHMICDTDPELGGAVQLMGLLRTLVDPENMLATANKTEKTEFLGFFYKHCMHVLTAPLLANTTEDKPSKDDFQTAQLLALVLELLTFCVEHHTYHIKNYIINKDILRRVLVLMASKHAFLALCALRFKRKIIGLKDEFYNRYIMKSFLFEPVVKAFLNNGSRYNLMNSAIIEMFEFIRVEDIKSLTAHVIENYWKALEDVDYVQTFKGLKLRFEQQRERQ-DNPKLDSMRS----ILRN-HRYRRDARTLEDEEEMWFNTDEDDMED--------------------GEAVVSPSDKTKNDDDIMDPIS--------------------------------------------------KFMERKKLKESEEKEVLL-KTNLSGRQSP----------------------SFKLSLSSGTKTNLTSQSSATSLPGSPGSP-----------------------------------GSP--------------------------GSPGSPGSVPKSTSQPAAITTKG-GLVGLVDYPDDDEDDDEDED---KEDTLPVSKKAKFES-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6IN85-1", "uniprot_id": "P4R3A_HUMAN", "id": "Q6IN85-1", "name": "Serine/threonine-protein phosphatase 4 regulatory subunit 3A", "aln": "-----------------------MTDTRRRVKVYTLNEDRQWDDRGTGHVSSGYVERLKGMSLLVRAESDGSLLLESKINPNTAYQKQQDTLIVWSEAENYDLALSFQEKAGCDEIWEKICQVQGKDPSVDITQDLVDESEEERFDDMS--SPGLELPSCELSR-----LEEIAELVASSLPSPLRREKLALALENEGYIKKLLELFHVCEDLENIEGLHHLYEIIKGIFLLNRTALFEVMFSEECIMDVIGCLEYDPALSQPRK-HREFLT-KTAKFKEVIPISDPELKQKIHQTYRVQYIQDMVLPTPSVFEEN-MLSTLHSFIFFNKVEIVGMLQED--EKFLTDLFAQLTDEATDEEK------RQELVNFLKEFCAFSQTLQPQNRDAFFKTLSNMGILPALEVILGMD-DTQVRSAATDIFSYLVEYNPSMVREFVMQEAQQNDDVSKKLTEQKITSKDILLINLIIEHMICDTDPELGGAVQLMGLLRTLVDPENMLATANKTEKTEFLGFFYKHCMHVLTAPLLANTTEDKPSKDDFQTAQLLALVLELLTFCVEHHTYHIKNYIINKDILRRVLVLMASKHAFLALCALRFKRKIIGLKDEFYNRYIMKSFLFEPVVKAFLNNGSRYNLMNSAIIEMFEFIRVEDIKSLTAHVIENYWKALEDVDYVQTFKGLKLRFEQQRERQ-DNPKLDSMRS----ILRN-HRYRRDARTLEDEEEMWFNTDEDDMED--------------------GEAVVSPSDKTKNDDDIMDPIS--------------------------------------------------KFMERKKLKESEEKEVLL-KTNLSGRQSP----------------------SFKLSLSSGTKTNLTSQSSTTNLPGSPGSP-----------------------------------GSP--------------------------GSPGSPGSVPKNTSQTAAITTKG-GLVGLVDYPDDDEDDDEDED---KEDTLPLSKKAKFDS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5SP90-1", "uniprot_id": "PP4R3_DANRE", "id": "Q5SP90-1", "name": "Serine/threonine-protein phosphatase 4 regulatory subunit 3", "aln": "-----------------------MTDTRRRVKVYTLNEDRQWDDRGTGHVSSAYVERLKGMSLLVRAESDGSLLLESKINPNTAYQKQQDTLIVWSEAENYDLALSFQEKAGCDEIWEKICQVQGKDPSVDITQELIDESEEERFDDMS--SPGLELPPCELSR-----LEEVAELVASSLPSPLRREKLALALENEGYIRKLLELFRVCEDLENREGLHHLYDIIKGIFLLNRTALFEVMFSEECIMDVIGCLEFDPSLPQPRR-HREFLT-TTARFKEVIPISDPELRQKIHQTYRVQYIQDMVLPTPSVFEEN-MLSTLHSFIFFNKVEIVGMLQDD--EKFLTELFAQLTDEATDDDK------RHELVNFLKEFCAFSQTLQPQNRDAFFKTLSNMGILQALEVILGMD-DVQVRGAATDIFSYLVEYNPSMVREFVMQESQQNDD-------------DILLINLIIEHMICDTDPELGGAVQLMGLLRTLVDPENMLATANKTEKTEFLSFFYKHCMHVLSAPLLANTTEEKPSKDDFQTCQLLALIVELLTFCVEHHTYHIKNYIINKDILRRVLVLTASQHAFLALCALRFMRKIIGLKDEFYNRYIMRNFLFEPVVKAFLNNGSRYNLINSAIIEMFEYVRVEDVKSLTAHIIENYWKGLEDVDYVQTFKGLKLRYEQQRERQ-DNPKLDSMRS----ILRN-HRFRRDARTLEDEEEMWFNTDEEDLED--------------------GEAVVPPSDKMKNDEDLMDPIS--------------------------------------------------KFMERKKLKDSEEKEVLTGKASLSGRQSP----------------------SFKLSFSSSPKASLSSPPTASLHPGSPGSP-----------------------------------SSP--------------------------GTG------ARSSPPSAAVTTKG-GLVGLVDYPDDDEEDEDEEDADSKEESPPLSKKSKLSS-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VFS5-1", "uniprot_id": "PP4R3_DROME", "id": "Q9VFS5-1", "name": "Serine/threonine-protein phosphatase 4 regulatory subunit 3", "aln": "----------------------MTTDTRRRVKLYALNAERQWDDRGTGHVSSTYVERLKGISLLVRAESDGSLLLESKIQPDTAYQKQQDTLIVWSEGDNFDLALSFQEKAGCDEIWEKICQVQGKDPSVEITQDIVEESEDERFEDMSDTAPPIELPPCELSR-----LEDISETIQSCLSTPLRKEKLSMALESESYIKKLLNLFHVCEDLDNTEGLHHLFEIFKNIFLLNKNALFEIMFADDTIFDVVGCLEYDPSVSQPKK-HRQYLK-QLAKFREAVPIKNLDLLAKIHQTFRVQYIQDIILPTPSVFVEDNMLNTLSSFIFFNKVEIVTMIQDD--ERYLLDVFAVLTDPTTGDAK------RRDTVLFLKEFCNYAQNLQPQGKDSFYKTLTCLGILQALELTLVMN-DKKTKSASIDILTAIVEFSPLVVRNYTLNQANRPEV-------------ERMLLNIAIEQMLNDSEPELGIAVQLMGIVKILLEPENMLT-----EKGDFLNFFYKYSVQTLVAPVILNTIGDRPQNEDYQTAQLLGIVLDILSFCVEHHSYHIKNFLLQKDLLKRILVLMKSTHTFLVLGALRLLRKIIALKDEFYNRHIVKCNLFAPVVDAFIRNNGRYNLLESAILELFEFIKLEDIRTLCVYFVENFSKIFDEIEYVQTFKYLKNRYDQYQDRLKDRDKMENRTDGGLPIIRSGGRFRRDQRQMEEEEEMWFNEEDDFTEEIDTYNNVMKSVSEKNGPQTQNQQKSSPPHSTSPHSGLLGSLSTTASSTATSATSGAPVASGSSSPEAISADEQTQAAVHLAAAALQHHQQQQQQQQQNPFQQQTQPEIAELQQQLSSVEAPQSQELELSQSAAASASPTSSSSSLEASTSSSSASSSSSSSSSSSPPGSSAAASLCDSATVAAVAASQFLSTIATAMAASVTAAAATNSSPSISPAPAVSSPDIENADAQLPPSDDASSPASGEQDANSTEGTSSEADKTTAKKGLVDYESDSGEDDYEEDE--YSEGPQAQKRARQA--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40164-1", "uniprot_id": "PP4R3_YEAST", "id": "P40164-1", "name": "Serine/threonine-protein phosphatase 4 regulatory subunit 3", "aln": "MSLPGTPTTSPTPMDEDTEQAVSVNTEPKRVKVYILENN-EWKDTGTGFCIGEVDEGKFAYLVVSDEDSPTETLLKSKLEGNIEYQRQEETLIVWKDLGGKDIALSFEESMGCDTLCEFIVHVQR-NIESNISLVTVKSSDNGLGSVHDIITGPVTLPSNDQQQNSQTLLEALKILNENTSFDFLKNETIEFILQSN-YIDTLISHFHKAEEEKIPKDLFLLSNIIKTLILYNKRDILESMVEDDRIMGIVGILEYDTEYPTSKANHRKYLGSKGPNFKEVIPLENEDLKIIMKKCFRLQFLKDVVLVR---FLDDHNFNLISEIVMDLETCIIDFLQVGTFLDRLIELYDTKTLPESSSEKEKFVQKRKDGIRLLQQCVQMSINLDAVDRSKFYKTLVRKGLFKVLDYAFHMETDSNVRILATDTIITIIEHDILLIHNVQNEDSFKRQH--------------KSAPDDKSSHRKYPQDYSSSTDSKLLLILSTILLSDRSPGLREQVVQALNTLLHPEGCVGNGEGSYDLMGRSNYEAKN-------TSEDFPSFSYGLNSDSINLNNYHYSSDEMNNLEPESESEFQVMEYFANFYNKIAPILFGPLIKKDITT---EMAEIDGQIEKVTKDDLLLIHLVKLVSFVCTEHDRVLSRRFILENGILDSVSKLIGGNHMMQLRLTAVRCIK-NLMCLDDKYYHRYMISKN---LYAPVFKLFQENIDKNNLANSCIQDFFR--------------IIITECRAYQSDGHNRKEKTNGSYD-------------------------------------------------GNGNDVKTNVNNNRTNFTILNKYLVQTYGD----------------------VLRKATDIPFIQDMLETGEENQPDHSSFEN---------------------------------------------------------------SIEGGNDISVNMSTDGFASNHLEDIDIKNVKRLHSEIEHFENDPHYSGDQLAFKKSVDQMNAST", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :***:* *: : :*.* ***. . * . :: :* . **:**:: : **:*::*****.: . *:****:*. *** : * * :** : . :*: :..*:: . . : : **. : .: ** : . *:.*.: : *:.: ** .*:. *: .*: . :.*. * :*:* ::* *: ::* *. :: *:.::* **:*. . .: **::* ..*:*.:*:.: :* ::: :*:*:::*::* * :: :. : .::: :. *: ::* . * ::: * :.. * *:: : :*:: : .*:. .:. *:*** *:: .*: : *: * :.: : * : ::*.. :::: ::: : : : .: : . . :*: :: :: .:. : :. : .: .. : :: . . ::: :: .: :::*: ..* :..: * . .: * : * . : :: * . :.. :.: : :*: ::::..:: *. : * .: : . . : : :: * : : ::. * :. : :*: * :. :: : .. . .. .. . : : : :. . :. : * . :. : . . . . *. .: :: : .: .: . : : . . . ", "identical_positions": 110, "similar_positions": 303, "identity": "10.58%" }, { "cls_id": "homologset.agr.RGD:1309060", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4A9L1-1", "uniprot_id": "D4A9L1_RAT", "id": "D4A9L1-1", "name": "", "aln": "-MSFPQLGYPQYLSAAGPGAYGGE---------------------------------------------------RPGMLAAAAAAA--------------------------------AAASSGRPGTAELGAGAGAAAVTSVLGMYAAAGPYAGA----------------------------PNYSAFLPY-AADLSLFSQMGSQYELKDN-----------PGVHPATFAAHTTPAYYPYG---------QFQYGDPGRPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKVTWGARSKDQEDGALFGSDTEGDPEKAEDDEE-----------IDLESIDIDQIDERDGDQSNEDEEDKVEAPRARVAPPAPARDQSSPLSAAETLKSQDSPLGLAKEVSEPGSTRLLS------------------------------------PGAAAVGLQGAPHSKPKIWSLAETATSPDGAP-------KASPPPPSSHASAHGPPSGSPLQHPAFLPSHGLYTCHIGKFSNWTNGAFLAQGSLLNMRSFLGVSAPHAAPHGPHVTAPPPPQLPVQVATGVLHGEKASASSSPALPERD-----------------------LVTRPDSPPQQ--------------LKSPFQPVRDNSLAPQEGTPRILAALSSA----------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P81068-1", "uniprot_id": "IRX1_MOUSE", "id": "P81068-1", "name": "Iroquois-class homeodomain protein IRX-1", "aln": "-MSFPQLGYPQYLSAAGPGAYGGE---------------------------------------------------RPGVLAAAAAAA--------------------------------AAASSGRPGTAELGAGAGAAAVTSVLGMYAAAGPYAGA----------------------------PNYSAFLPY-AADLSLFSQMGSQYELKDN-----------PGVHPATFAAHTTPAYYPYG---------QFQYGDPGRPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKVTWGARSKDQEDGALFGSDTEGDPEKAEDDEE-----------IDLESIDIDQIDERDGDQSNEDEEDKAEAPRARVAPPASARDQSSPLSAAETLKSQDSPLGLVKEVSEPGSTRLLS------------------------------------PGAAAVGLQGAPHSKPKIWSLAETATSPDGAP-------KASPPPPSSHASAHGPPSGSPLQHPAFLPSHGLYTCHIGKFSNWTNGAFLAQGSLLNMRSFLGVSAPHAAPHGPHLTAPPPPQPPVQVATGVLHGEKASARSSPALPERD-----------------------LVTRPDSPPQQ--------------LKSPFQPVRDNSLAPQEGTPRILAALPSA----------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P78414-1", "uniprot_id": "IRX1_HUMAN", "id": "P78414-1", "name": "Iroquois-class homeodomain protein IRX-1", "aln": "-MSFPQLGYPQYLSAAGPGAYGGE---------------------------------------------------RPGVLAAAAAAA--------------------------------AAASSGRPGAAELGGGAGAAAVTSVLGMYAAAGPYAGA----------------------------PNYSAFLPY-AADLSLFSQMGSQYELKDN-----------PGVHPATFAAHTAPAYYPYG---------QFQYGDPGRPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKVTWGARSKDQEDGALFGSDTEGDPEKAEDDEE-----------IDLESIDIDKIDEHDGDQSNEDDEDKAEAPHAPAAPSALARDQGSPLAAADVLKPQDSPLGLAKEAPEPGSTRLLS------------------------------------PGAAAGGLQGAPHGKPKIWSLAETATSPDGAP-------KASPPPPAGHPGAHGPSAGAPLQHPAFLPSHGLYTCHIGKFSNWTNSAFLAQGSLLNMRSFLGVGAPHAAPHGPHLPAPPPPQPPVAIAPGALNGDKASVRSSPTLPERD-----------------------LVPRPDSPAQQ--------------LKSPFQPVRDNSLAPQEGTPRILAALPSA----------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PF69-1", "uniprot_id": "A0A8M1PF69_DANRE", "id": "A0A8M1PF69-1", "name": "", "aln": "-MSFPQLGYPQYLSAS-QAVYGGD---------------------------------------------------RPGVLTPSSRAG--------------------------------SAEIGG-------SASAAAAAVSSVLGMY----PYA------------------------------HNYSAFLPYTSADLALFSQMGSQYDLKDS-----------PGVHPASFAAHTSPAFYPYG---------QFQYGDPARPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKVTWGARSKDDEN--IFGSDNEGDAEKNEDEEE-----------IDLESIDIDKIDDNDGDQSNEEDEDKRAELESLQEKRHASKEPSD---------------------GNNNTTRVLS------------------------------------PGRQG-GFQVPVSNKPKIWSLAETATSPDSAQ-------KPTSP-------------SVPVSHPAFLPSHGLYTCQIGKFHNWTNGAFLGQNSLLNVRSFLGVN-QHNHPAQQQQQQTGPASLQVLSAG---NTDKMPEDLSPKHIDRE-----------------------NVLRNESPTQP--------------LKSSFRPLHDSPRNQQESTQRVLTALSSA----------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24248-1", "uniprot_id": "ARA_DROME", "id": "Q24248-1", "name": "Homeobox protein araucan", "aln": "MAAYTQFGYGGFPSASQLLPPSVQTTEDASANVNVNVNEALVMTNAPAMSPTGGQDCQGSQPSGGAGGDASSGALSPNALSQNSNAATVVGAGGGSSAGGGGPADLATGGSLDGNGVGTTPTAGGAGGGGSCCENGRPIMTDPVSGQTVCSCQYDSARLALSSYSRLPAAS----VGVYGTPYPSTDQNPYQSIGVDSSAFYSPLSNPYGLKDTGAGPEMGAWTSAGLQPTTGYYSYDP-MSAYGGLLVSNSSYGASYDLAARRKNATRESTATLKAWLNEHKKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWEPKNRTDDDDDALVSDDEKDKEDLEPSKGSQGSVS----LAKDETKEEEDAIDE--DQKCLG--QANILRAGFGYPSAGSGSGGYPGGGGSSS---GHPGGYHPYHHQHPAYYQAGQQGG---MLPFHGENS----------KLQTDLGDPKNQLGRDCGVPIPATKPKIWSLADTVGCKTPPP--AYMGHQSMPLQQQQQQQQQQQQAQHQYPPSEAGRDQQLFNGAAAPYLRPHTTAYGGFLGATTQQLHTTNNSIPYSNMPPQQQQPQQQQQQLQQGGTIHTTGSSSGPIIPLQFHNRHPQQQQQLQQQSQSTASQRAMGFLEAQPDTPPQTPPNMKVLS--------GALSLLPTATQVPMTATCRSSNAFGFPASGYPMNFSARLGEYSPRDDYSSGNSSSSSSSSPQLQRNEAMFKPLFKKFTN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P54269-1", "uniprot_id": "CAUP_DROME", "id": "P54269-1", "name": "Homeobox protein caupolican", "aln": "MAAYAQFGYAGYPTANQLTTANTDSQSGHGG------GSPLSGTNEASLSPSGGSTATG----------LTAGPLSPGAVSQSSHHA---GHKGLSTS----PAEDVVGGDVP---VGLSSAAQDLPSRGSCCENGRPIITDPVSGQTVCSCQYDPARLAIGGYSRMALPSGGVGVGVYGGPYPSNEQNPYPSIGVDNSAFYAPLSNPYGIKDTSPSTEMSAWTSASLQSTTGYYSYDPTLAAYG--------YGPNYDLAARRKNATRESTATLKAWLSEHKKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWEPKNKTEDDDDGMMSDDEKEKDAGDGGKLSTEAFDPGNQLIKSELGKAEKEVDSSGDQKLDLDREPHNLVAMRGLAPYATPPGAHPMHAAYSSYAQSHNTHTHPHPQQMQHHQQQQQQQQNQQQLQHHQMDQPYYHPGGYGQEESGEFAAQKNPLSRDCGIPVPASKPKIWSVADTAACKTPPPTAAYLGQNFYPPSSADQQLPHQPLQQHQQQQLQQLQQQQQHHHHPHHHHPHHSMELG----SPLSMMSSYAGGSPYSRIPTAYTEAMGMHLPSSS-----SSSSSTGKLPPTHIH---PAPQR--------------VGFPEIQPDTPPQTPPTMKLNSSGGSSSSSGSSHSSSMHSVTPVTVASMVNILYSNTDSGYGHGHSHGHGHG---HGHGLGHGHGLGHGHGHMGVTSNAYLTEGGRSGS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::.*:** : :* . : *. :: : . :. . .. . . .* * * : ..: . . :::: :.. * :**. ..::.:: * .** .*. ..* ********:******.**:****************************************:** .:.: ::: : ** * : : : : . * . :. : **. : : . : ******:*:*. . . : . .: . . . . . . . * . : ::*.* .. . : . ", "identical_positions": 91, "similar_positions": 100, "identity": "12.04%" }, { "cls_id": "homologset.agr.RGD:1309061", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LKE1-1", "uniprot_id": "A0ABK0LKE1_RAT", "id": "A0ABK0LKE1-1", "name": "", "aln": "-------MFVKSETLELKEEEE-------------------VLMLLGSASPASATLTPMSSSADEEEDEELRRPGAARGQRGAEAGQGVQGS-------SASGAGGCRPGRLLGLVHECKR-----RPSRARAVSRG----AKTAETVQRIKKTRRLKANNRERNRMHNLNAALDALREVLPTFPEDAKLTKIETLRFAHNYIWALTETLRLADHCAGGGS-LQGALFS---------EAVLLSPG-----------------------------------AALGASGDSPSPSSSWSCTNSPASSS----NSTSPYSCTLSP---ASP----------------------GSDVD---------YWQPPP----PEKHRYAPHLPLARDCI------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70447-1", "uniprot_id": "NGN2_MOUSE", "id": "P70447-1", "name": "Neurogenin-2", "aln": "-------MFVKSETLELKEEEE-------------------VLMLLGSASPASATLTPMSSSADEEEDEELRRPGSARGQRGAEAEQGVQGS-------PASGAGGCRPGRLLGLMHECKR-----RPSRSRAVSRG----AKTAETVQRIKKTRRLKANNRERNRMHNLNAALDALREVLPTFPEDAKLTKIETLRFAHNYIWALTETLRLADHCAGAGG-LQGALFT---------EAVLLSPG-----------------------------------AALGASGDSPSPPSSWSCTNSPASSS----NSTSPYSCTLSP---ASP----------------------GSDVD---------YWQPPP----PEKHRYAPHLPLARDCI------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H2A3-1", "uniprot_id": "NGN2_HUMAN", "id": "Q9H2A3-1", "name": "Neurogenin-2", "aln": "-------MFVKSETLELKEEED-------------------VLVLLGSASPALAALTPLSSSADEEEEEEPGASGGARRQRGAEAGQGARGG-------VAAGAEGCRPARLLGLVHDCKR-----RPSRARAVSRG----AKTAETVQRIKKTRRLKANNRERNRMHNLNAALDALREVLPTFPEDAKLTKIETLRFAHNYIWALTETLRLADHCGGGGGGLPGALFS---------EAVLLSPGGA--------------------------------SAALSSSGDSPSPASTWSCTNSPAPSSSVSSNSTSPYSCTLSP---ASPA---------------------GSDMD---------YWQPPP----PDKHRYAPHLPIARDCI------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O16867-1", "uniprot_id": "TAP_DROME", "id": "O16867-1", "name": "Basic helix-loop-helix neural transcription factor TAP", "aln": "MAACYNAYSAGSQSFEFDEDDDDASFDSGYEKSFETEAQLSSRRRLDFGTPPTPAIPQPYSGGTWDAVPLSSPPAGFVGLLDTSSNHSTRSGRTLVEHLNSRATNGVFDPPLTSTPVKSPEDPNAPRPKRKYAVGKNRVTRSRSPTQVVKIKRFRRMKANDRERNRMHNLNDALEKLRVTLPSLPEETKLTKIEILRFAHNYIFALEQVLESGGSINLDLEKLQNFTLSGERITKELFDALFVNPQPYPLFGRMFPYGQGMAPLAQHQTAPASHAEQPPAMGGFQHGMDYPQQPPGFDFTGSMRFYHQQQQQPHQPHHLQPNPQQESSPQQFSQEKYDLFRGSFDAAANLHSTNLDSGIHQQSSFYSQTPPWKDYPEDQAHVHPVPHQHSYKNFAPQV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *:::*:.*::: *. .:*. .::. *.. : ... .:.: :..:.. : .: * * . .. . **.* **.:. :::. * :**: **:***:********** **: ** .**::**::****** ********:** :.*. .. * . :: :*:::.* ..: . * *. .. :. *.* :. .*: .* :** .:::* * *.** *:.: :. :* :. ", "identical_positions": 74, "similar_positions": 101, "identity": "18.59%" }, { "cls_id": "homologset.agr.RGD:1309062", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U3Z3-1", "uniprot_id": "ISOC2_RAT", "id": "Q5U3Z3-1", "name": "Isochorismatase domain-containing protein 2", "aln": "-MAAARASLGRIFPESSILFLCDMQEKLRDRVLYFPQIVSMAARMLKVARILDVPVLLTEHYPQGLGPTVPELGAQGVRTMS-KTSFSMVPP-LQQELDKLP--QLKSVLLCGIETQVCILNTALDLLDRGLQVHVAVDACSSQSEMNRLVALARMQHSGVFLSTSEALTLQLIKDAAHPQFKEIQKILKEPVPEIGLLGFFQGMNNPLLPNSRP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DCC7-1", "uniprot_id": "ISC2B_MOUSE", "id": "Q9DCC7-1", "name": "Isochorismatase domain-containing protein 2B", "aln": "-MGAAKASLGRIFPESSILFLCDMQEKLRDRILYFPQIVSKAARMLKVAQMLEIPVLLTEHYPQGLGPTVPELGAQGLRTMS-KTSFSMVPP-LQQELDKLP--QLQSVLLCGIETQGCILHTALDLLDRGLQVHVAVDACSSQSEMNRLVALARMQQSGVFLSTSEVLILQLVKDAAHPQFKEIQKILKEPVTDIGLLGFFQGKKNSLLPNSRT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96AB3-1", "uniprot_id": "ISOC2_HUMAN", "id": "Q96AB3-1", "name": "Isochorismatase domain-containing protein 2", "aln": "-MAAARPSLGRVLPGSSVLFLCDMQEKFRHNIAYFPQIVSVAARMLKVARLLEVPVMLTEQYPQGLGPTVPELGTEGLRPLA-KTCFSMVPA-LQQELDSRP--QLRSVLLCGIEAQACILNTTLDLLDRGLQVHVVVDACSSRSQVDRLVALARMRQSGAFLSTSEGLILQLVGDAVHPQFKEIQKLIKEPAPDSGLLGLFQG-QNSLLH----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0JME6-1", "uniprot_id": "ISOC2_DANRE", "id": "A0JME6-1", "name": "Isochorismatase domain-containing protein 2", "aln": "-----MAGIGRLSTKGSVLLLCDMQEKFRPTIFQFTNVVSNAARLLQACRILNIPQILTEQYPKGLGPTVPELGAEGLKPHT-KTSFSMMTESVQSSLKSMG--DPQQVILCGIEAQACIACTAYDLLERGMEVHIVADAVSSRSQTDRLFALSRLRQSGVFLNTTEGVLLQLVQDAKHPNFKEIQKLLAHPSPDTGLLAFFSSL----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W127-1", "uniprot_id": "Q9W127_DROME", "id": "Q9W127-1", "name": "Isochorismatase-like domain-containing protein", "aln": "MALRR----CHLNPKKTLFLLCDIQEKFRPAMPLFDNMIKNVDKLTRAGKALDVPLIVTEHYPEKLGKTVAQLDVSHAKLVSGKTLFSMFTPEVKAVIKDIFNDKPEDVVLYGLESHICVEQTAIDLLEQNINVYIVADCCSSRLNQDRDLALDRLRQAGCVITTSESVIFDLVRDKNNPKFDVVRKLVNQPSVDMELTRNGSGVPAGSAKL---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V9X3-1", "uniprot_id": "Q9V9X3_DROME", "id": "Q9V9X3-1", "name": "Isochorismatase-like domain-containing protein", "aln": "MSKVRGPALYRLVPSKTLFMLCDVQEKFKPAIPLLSSLIENTTKLLAAGKVFQVPLLVTEQYPERLGKTVCELDIKHACANISKTMFSMLVEPVRKSMTDIFGGKPKTVVLFGLETHVCVEQTAFDLVNDEIDVWLVADCCASRHNQDRDLALERLRHIGCNIATSESVIFNLLGDKNNKSFKEITPLVKKISADMQLCRVSKN-----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: . ::::***:***:: : : .::. . :: . : :::* ::**:**: ** ** :*. . ** ***. :: : . . . *:* *:*:: *: *: **:: ::* :..*. :*: : :* .** *::: * : *:* : ::*: * : .*. : :: . : * .. ", "identical_positions": 43, "similar_positions": 76, "identity": "20.0%" }, { "cls_id": "homologset.agr.RGD:1309063", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P42226-1", "uniprot_id": "STAT6_HUMAN", "id": "P42226-1", "name": "Signal transducer and activator of transcription 6", "aln": "MSLWG-LVSKMPPEKVQRLYVDFP--QHLRHLLGDWLES-QPWEFLVGSDAFCCNLASALLSDTVQHLQASVGEQGEGSTILQHISTLESIYQRDPLKLVATFRQILQGEKKAVMEQFRHLPM-------------------------------------------PFHWKQEELKFKTGLRRLQHRVGEIHLLREALQKGAEAG------------------QVSLHSLIETPANGTGPSEALAMLLQETTGELEAAKALVLKRIQIWKRQQQLAGNGAPFEES----LAPLQERCESLVDIYSQLQQEVGAAGGELEPKTRASLTGRLDEVLRTLVTSCFLVEKQPPQVLKTQTKFQAGVRFLLGLRFLGAPAKPPLVRADMVTEKQARELSVP----QGPGAGAESTGEIINNTVPLENSIPGNCCSALFKNLLLKKIKRCERKGTESVTEEKCAVLFSASFTLGPGKLPIQLQALSLPLVVIVHGNQDNNAKATILWDNAFSEMDRVPFVVAERVPWEKMCETLNLKFMAEVGTNRGLLPEHFLFLAQKIFNDNSLSMEAFQHRSVSWSQFNKEILLGRGFTFWQWFDGVLDLTKRCLRSYWSDRLIIGFISKQYVTSLLLNEPD--GTFLLRFSDSEIGGITIAHVIRGQDGSPQIENIQPFSAKDLSIRSLGDRIRDLAQLKNLYPKKPKDEAFRSHYKPEQMGKDGRGYVPATIKMTVERDQPLPTPELQMPTMVPSYDLGMAPDSSMSMQLGPDMVPQVYPPHSHSIPPYQGLSPEESVNVLSAFQEPHLQMPPSLGQMSLPFDQPHPQGLLPCQPQEHAVSSPDPLLCSDVTMVEDSCLSQPVTAFPQGTWIGEDIFPPLLPPTEQDLTKLLLEGQGESGGGSLGAQPLLQPSHYGQSGISMSHMDLRANPSW-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P52633-1", "uniprot_id": "STAT6_MOUSE", "id": "P52633-1", "name": "Signal transducer and transcription activator 6", "aln": "MSLWG-LISKMSPEKLQRLYVDFP--QRLRHLLADWLES-QPWEFLVGSDAFCYNMASALLSATVQRLQATAGEQGKGNSILPHISTLESIYQRDPLKLVATIRQILQGEKKAVIEEFRHLPG-------------------------------------------PFHRKQEELKFTTALGRLQHRVRETRLLRESLQQGAKTG------------------QVSLQNLIDPPVNGPGPSEDLATMLQGTVGDLEATQALVLKRIQIWKRQQQLAGNGTPFEES----LAGLQERCESLVEIYSQLQQEIGAASGELEPKTRASLISRLDEVLRTLVTSSFLVEKQPPQVLKTQTKFQAGVRFLLGLQFLGTSAKPPMVRADMVTEKQARELSLA----QGPGTGVESTGEIMNNTVPLENSIPSNCCSALFKNLLLKKIKRCERKGTESVTEEKCAVLFSTSFTLGPNKLLIQLQALSLPLVVIVHGNQDNNAKATILWDNAFSEMDRVPFVVAERVPWEKMCETLNLKFMAEVGTSRGLLPEHFLFLAQKIFNDNSLSVEAFQHRCVSWSQFNKEILLGRGFTFWQWFDGVLDLTKRCLRSYWSDRLIIGFISKQYVTSLLLNEPD--GTFLLRFSDSEIGGITIAHVIRGQDGSSQIENIQPFSAKDLSIRSLGDRIRDLAQLKNLYPKKPKDEAFRSHYKPEQMGKDGRGYVSTTIKMTVERDQPLPTPEPQMPAMVPPYDLGMAPDA--SMQLSSDMG---YPPQ--SIHSFQ--SLEESMSVLPSFQEPHLQMPPNMSQITMPFDQPHPQGLLQCQSQEHAVSSPEPMLCSDVTMVEDSCLTQPVGGFPQGTWVSEDMYPPLMPPTEQDLTKLLLENQGEAGG-SLGSQPLLQPSPYGQSGISLSHLDLRTNPSW-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q24151-1", "uniprot_id": "STAT_DROME", "id": "Q24151-1", "name": "Signal transducer and transcription activator", "aln": "MSLWKRISSHVDCEQRMAAYYEEKGMLELRLCLAPWIEDRIMSEQITPNTTDQLERVALKFNEDLQQKLLSTRTASDQALKFRVVELCALIQRISAVELYTHLRSGLQKELQLVTEKSVAATAGQSMPLNPYNMNNTPMVTGYMVDPSDLLAVSNSCNPPVVQGIGPIHNVQNTGIASPALGMVTPKVELYEVQHQIMQSLNEFGNCANALKLLAQNYSYMLNSTSSPNAEAAYRSLIDEKAAIVLTMRRSFMYYESLHEMVIHELKNWRHQQAQAGNGAPFNEGSLDDIQRCFEMLESFIAHMLAAVKELMRVRLVTEEPELTHLLEQVQNAQKNLVCSAFIVDKQPPQVMKTNTRFAASVRWLIGS-QLGIHNNPPTVECIIMSEIQSQRFVTRNTQMDNSSLSGQSSGEIQNASSTMEYQQNNHVFSASFRNMQLKKIKRAEKKGTESVMDEKFALFFYTTTTVN--DFQIRVWTLSLPVVVIVHGNQEPQSWATITWDNAFAEIVRDPFMITDRVTWAQLSVALNIKFGSCTG--RSLTIDNLDFLYEKLQREE-------RSEYITWNQFCKEPMPDRSFTFWEWFFAIMKLTKDHMLGMWKAGCIMGFINKTKAQTDLLRSVYGIGTFLLRFSDSELGGVTIAYVNE----NGLVTMLAPWTARDFQVLNLADRIRDLDVLCWLHPSDRN---------------------------------------------------------------------------------------------------------------ASPVKRDVAFGEFYSKRQE-----PEPLVLDPVTGYVKSTLHVHVCRN------------------------------GENGSTSGTPHHAQESMQLGNGDFGMADFDTITNFENF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "M0R7R7-1", "uniprot_id": "M0R7R7_RAT", "id": "M0R7R7-1", "name": "", "aln": "----------------------------------------------------MAGGIKVAVWSAVGPGPGCCGAGGGGAAWLLLVVAGCVVGCSAGIDVNVVMLQESQVDMNSSQQ--------------------------------------------------FCYKNVLIPKWHDIWTRIQVRVNSSKLVRVTQVD-----------------------SEERLKELEQFSVWNSLSSFLKEKLNDTYVNVGLYSTKTCLKVEIIEKDTKYS-------------VIVTRRFDPKLFLVFLLGLTLFFCGDLLSRSQIFYYSTGMSVGIVASLLIVIFMISKLMPKRSPIYVILVGGWSFSLYLIQLVFKNLQEIWRCYWHYLLS------------YILTVGFMSFAVCYKYGPLENERSINLLTWTLQLLGLGFMYSG-----------------------------IQIPHVAFALIVIALCTKNLEYPIYWLYS-----TYRRMCKASEKPVPPRLLTEEEYRIQGEVETQKALQELREFCNSP---------------ECSAWKTISRIQSPKR---FADFVEGSFHLTPNEVS----------------------------------VHEQEYG-------------------LGSILAQDEELSSEEEGSEDLPLTQNSFLT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . : : : :.: . : . * : : : : : :* .: : . . . . . . : :. : . .:: .:: : : . .:. . . .*: *::.* *: . : .. : : * .. . : : .:* . : : :: : * : *:: :::.::**. .:: : :. * ::: :: : :: . . :.* . . :*. : : * * ::. . :.** : . :.* * : . *:* .: . : .** . . ", "identical_positions": 25, "similar_positions": 125, "identity": "2.71%" }, { "cls_id": "homologset.agr.RGD:1309065", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GEK3-1", "uniprot_id": "A0A8I6GEK3_RAT", "id": "A0A8I6GEK3-1", "name": "EF-hand calcium-binding domain-containing protein 6", "aln": "MKRNGARLNAAKVNSTKSGSTKARDLMYKMSVLPEWHSLYLNTRKLPCARPHSSPCRTQRPIVHDLCRPFSSTTALANPVLSSLDVERILSQKISSKRDEIKKVFQILDPNHSQTVTKGELKRTITAFLMPLTKDQFQDLLAQIPITSLGNVPYLEFLSRFGG-IDININGIKRVNENEVDNGQTLK--EIQLTEKIFRNMRTIRKVFQLIDVNNTGTVQPQELRRVLETFCLKMKDEDYEMFSKQYNINSTTAVDYNAFLKNLSVKNETNFKHLLSNPAEPSKENQQGKIAK--RLTDATSSEDIWKNYSLDDLEKTFCQELVKSYEKIEKALSAGDPSKGGYISLNYLKVVLDTFTYRLPRRTFIQLMRRFGLKTTTKVNWKQFLTAVYERQGWEVSKTIPLKKRSSTEARNRFRKENIIKKLFKYSEERYTALKKALLIISPTPSGHVTWEDLRHVLNCVVVKLSDSEFNELKQTFDPEGTGTVKISSLLDVLDDSPKVRKMSPSTDTKTP----LPVAWDSVEELVLDALTRNHQAFYGMLQSYDLGDTGSITKNNFKKVMRVFCPYLSNEHLAKLSNKFQEVGSGKILYKRYLFSIGLGIPPPGSRLSSPKSQR-SEQFQIE-----QQDERTQPLRDKTTEIKNMTKEEVIDSLKRRIQQKDSVFRQEFLNISKDPDVKISQGEFRKVLERSGMPMNDCQYAMLASKLGFKNEDGMSYQDFTMGFEDSMLSGLETVPLQSRPTSKMNLDEHFVSAEECLRIFPKKLKDSFRDSYAAFFRIDTDRDGIISMHDLHRLLQYLLINMMDFEFERFLSLMGLRLSVTLNFREFQNLCEKRPWKSDEAPQRLIRCKQKVADSELACEQAHQYLIMKAKTRWADLSKNFIETDNEGNGILRRRDIKNSLYGFDIPLTPREFEKLWQNYDTEGRGYITYQEFLHRLGIRYSPKVHRPYKEDYFNFLGHFTKPKQVQEEIQELHQISE-----REKLLDHFEEISKALNAMEKSRP--VALGRVQKVLQECGCPLKEEELIIILKSLDVSVHNNQIDPVEFLRALEISWASKPHPKEKEESSP-------INFSKLNPDEVIKSMQEVVESSQPALVKAFSALDKEDTGFVKAMEFGDVLKSICQKLTDNQYHYFLRRLRLHLTA--NIHWKYFLENFSSFLDETADEWAENMPKVPPPECPKETSSREILARVQKAVTSHYHTIAQEFENFDTLKSNTVSRDEFRSICTRHVQILTDEQFDRLWSEMPVNAKGRLKYQDFLSKLSTERVPSPPMAAGDSGDSMVAQRGSSAPEVSQGARSTLSSPSRDLRAGLKSRSHPCTPV------GTPPLQNCEPIESRLRKQIQGCWRELLKECKEKDTDKQGSITAAEFLALIEKFKLDISREESQQLLVKYDMKNNGKFAYCDFIQSCVLLLKAKETSLMRRMRIQNADKMKEAGVETPSFYSALLRIQPKIVHCWRPMRRTFKTYDENGTGLLSVADFRKVLRQFSINLSEEEFFHVLEYYDKSLSSKISYNDFLRAFLQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P1E8-1", "uniprot_id": "EFCB6_MOUSE", "id": "Q6P1E8-1", "name": "EF-hand calcium-binding domain-containing protein 6", "aln": "MKRNGTRLNFAKANSTKSGSTRARDLMNKMSIIPEWHSLYSNTRKLPCSRPHSSPCKMQRTIFQDLCRPSSSTTAIANPVLSYLDIERILAQKISSRRDDIKKVFQILDRNHNQMVTKGDLKRVITAFLIPLTKDQFQDLLAQIPISSLGNVPYLEFLSRFGGGIDININGIKRVNENEVDNRRTVK--EVQLTEKIFRNMRSIRKVFQVMDVNNTGLVQPQELRRVLETFCLRMQDGDYEKFLEQYNIDKTTAVDYNAFLKNLSVKNDASFKYLLSNAAELSRETQQGKNGK--RLLDTGSSEDVWKNYSLDDLEKTFCQEFSKSYEKIEKALSAGDPSKGGYISLNYLKVVLDTFIYRLPRRIFIQLIRRFGLKTSTKINWKQFLTAIYERQKLEVSKTLPLKKRSSTEARNRSRKENIIKKLFKYSEDRYTALKKTLLIISSTPSGHITWEELRHILNCMVAKLNDSEFSELKQTFDPEGTGAVRVNSLLDVLDDSTKVRKMSPSTDTKTP----LPVAWDSVEELVLDSITRNLQAFYSMLQSYDLRDTGTIGKNNFRKVMRVFCPYLSNEHLVRFSSKFQEAGSGRILYKKFLLSIGVGIPPPTPPLSSPKVQL-SDQFQIEEPG--QQDERTQPSGEKTSEINNMTKEEVIDGLKHRIQQKDPVFRKQFLSISKEPDVKINQEEFRKVLERSGMPMNDCQYAMLASKLGFKNEEGMSYQDFTMGFEDCMLSGLETVPLQSRTASRTNMDEHFISAEECLRIFPKKLKESFRDVYSAFFRIDLDRDGIISMHDFHRLLQYLQLNMVDLEFERFLSLLGLRLSVTLNFREFQNLCEKRPWKSDEAPQRLIRCKQKVADSELACEQAHQYLIMKAKTRWADLSKNFIETDNEGNGILRRRDIKNSLYGFDIPLTPREFEKLWQNYDTEGRGYITYQEFLHRLGIRYSPKVHRPYKEDYFNFLGHFTKPKQVQEEIQELQQISE-----REKLMNHYEEISKAFNAMEKSKP--VALCRVQKVLQECGCPLKEEELISLLKSLDVSVHNNHIDPVEFLRALEISWASKARPKEKEESSPPP-----ISFSKVTPDEVIKTMQEVVESSQPALVEAFSALDKEDTGFVKAMEFGDVLRSVCQKLTDNQYHYFLRRLRLHLTP--NIHWKYFLENFSTFQDETADDWAENMPKAPPPMSPKETAHRDIVARVQKAVASHYHTIVQEFENFDTLKSNTVSRDEFRSICTRHIQILTDEQFDRLWSELPVNAKGRLKYQDFLSKLSIERVPSPPMAAGDSGESTMAQRGSSAPEFSQGTRSNLYSPPRDSRVGLKSRSHPCTPV------GTPPLQNCEPIESRLRKQIQGCWRELLRECKEKDTDKQGTISAAEFLALVEKFKLDISREESQQLIVKYDLKNNGKFAYCDFIQSCVLLLKAKETSLMRRMRIQNADKMKEAGMETPSFYSALLRIQPKIVHCWRPMRRSFKTYDKNGTGLLSVADFRKVLRQYSINLSEEEFFHVLEYYDKSLSSKISYNDFLRAFLQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5THR3-1", "uniprot_id": "EFCB6_HUMAN", "id": "Q5THR3-1", "name": "EF-hand calcium-binding domain-containing protein 6", "aln": "--------------------------MCKMAIIPDWLRSHPHTRKFTHSRPHSSPCRVYSRNGSPNKFRSSSTTAVANPTLSSLDVKRILFQKITDRGDELQKAFQLLDTGQNLTVSKSELRRIITDFLMPLTREQFQDVLAQIPLSTSGTVPYLAFLSRFGG-IDLYINGIKRGGGNEMNCCRTLRELEIQVGEKVFKNIKTVMKAFELIDVNKTGLVRPQELRRVLETFCMKLRDEEYEKFSKHYNIHKDTAVDYNVFLKNLSINNDLNLRYCMGN-QEVSLENQQAKNSKKERLLGSASSEDIWRNYSLDEIERNFCLQLSKSYEKVEKALSAGDPCKGGYVSFNYLKIVLDTFVYQIPRRIFIQLMKRFGLKATTKINWKQFLTSFHEPQGLQVSSKGPLTKRNSINSRNESHKENIITKLFRHTEDHSASLKKALLIINTKPDGPITREEFRYILNCMAVKLSDSEFKELMQMLDPGDTGVVNTSMFIDLIEENCRMRKTSPCTDAKTP----FLLAWDSVEEIVHDTITRNLQAFYNMLRSYDLGDTGRIGRNNFKKIMHVFCPFLTNAHFIKLCSKIQDIGSGRILYKKLLACIGIDGPPTVSPVLVPKDQLLSEHLQKDEQQQPDLSERTKLTEDKTTLTKKMTTEEVIEKFKKCIQQQDPAFKKRFLDFSKEPNGKINVHDFKKVLEDTGMPMDDDQYALLTTKIGFEKE-GMSYLDFAAGFEDPPMRGPETTPPQPPTPSKSYVNSHFITAEECLKLFPRRLKESFRDPYSAFFKTDADRDGIINMHDLHRLLLHLLLNLKDDEFERFLGLLGLRLSVTLNFREFQNLCEKRPWRTDEAPQRLIRPKQKVADSELACEQAHQYLVTKAKNRWSDLSKNFLETDNEGNGILRRRDIKNALYGFDIPLTPREFEKLWARYDTEGKGHITYQEFLQKLGINYSPAVHRPCAEDYFNFMGHFTKPQQLQEEMKELQQSTEKAVAARDKLMDRHQDISKAFTKTDQSKTNYISICKMQEVLEECGCSLTEGELTHLLNSWGVSRHDNAINYLDFLRAVENSKSTGAQPKEKEESMP-------INFATLNPQEAVRKIQEVVESSQLALSTAFSALDKEDTGFVKATEFGQVLKDFCYKLTDNQYHYFLRKLRIHLTP--YINWKYFLQNFSCFLEETADEWAEKMPKGPPPTSPKATADRDILARLHKAVTSHYHAITQEFENFDTMKTNTISREEFRAICNRRVQILTDEQFDRLWNEMPVNAKGRLKYPDFLSRFSSETAATP-MATGDS---AVAQRGSSVPDVSEGTRSALSLPTQELRPGSKSQSHPCTPASTTVIPGTPPLQNCDPIESRLRKRIQGCWRQLLKECKEKDVARQGDINASDFLALVEKFNLDISKEECQQLIIKYDLKSNGKFAYCDFIQSCVLLLKAKESSLMHRMKIQNAHKMKEAGAETPSFYSALLRIQPKIVHCWRPMRRTFKSYDEAGTGLLSVADFRTVLRQYSINLSEEEFFHILEYYDKTLSSKISYNDFLRAFLQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P241-1", "uniprot_id": "A0A8M1P241_DANRE", "id": "A0A8M1P241-1", "name": "", "aln": "------MRPRSAVESWVSASAQMPQISSNLDLRPMTQGLTIIPRAKSASRLSSGDFSRRNTLKSD---SASSVQSVADENLSLVDIENLLLEKVKDRKDDLKAAFEAFDQEGNKTVTKGEFRRVIEGFLVPLTQSQFESLLAQLELKENGTVSYMEFLRRHCK-VSSTVGRIPSKSGRYRN--LSLGELQCRLRDKMRGHLKNITRAFRLFDYNNDGQIQQHELRKILEGYCFPMSQLEFHRLWSHYSMNNADTISYKVFLEKLGVDCENYRKIPPDSVQLALNWDAVSRSTTRPKSKTSLRRFSGKSRDNLDDIQIRFLSKMKKDHSLVEKALQAFDISDSGFVSLEDLRSILSNFLFAMDDTIFRELLKRFGVSNTEPVKWKIFLGLFKD--------DITVQKDSVPATADTCSIDAILSKLRQH------VLNQPLLDLDKSATGFISRNELFSALENMN--LTDEQFTVLADFLDVDHTDAINCQQFLDLLHLQNPVVQTPKLNEKAQARLNTAITAQNAIEKILKEKISENYDVLMESITNTTQNQNDTISPEDFRRLIQHVLP-LSDHHFIKLCEPFFEDGN--VNYKLFLKSFGPPEKIDSTLSMIEREEK--------------------AHEASILDIKAQAIKDVVLRKLKDRLQRKGVTLQDYLMSSRITKSSLNLRDVCKILDDCGVFLEGHQFQMLIESLGFNLG-PVSVADFVDKYEEVTMPE------KDDSQTKNAKFSTLLTAEDCLGQLKKRIKEYHGDALTAFYLMDKNRDGLVNRIDFRALFDSLMFVTQEREYQRLLDMLGLTPGATLNYTEFHKKVQS----SDKMKLHHHDGTLKDGILDNACDQVHEYLAAIAHKRPSEISKVFCHLGNDCKSIMTKNGLKQLLFKYSMPITPNEFEILWSRYDKESKGFLTQKEFLSKLKITSDEDQER---------QEQPTATPDLEIMLQNLRKWIG----------IDFESVSGSLVVLDKNKDGHVTVTDLLSLLHRHGFQLTEAQFAHLLSLLGFDSDLKQLPYLDFLKHLVGPPVSSWSVFDPSQGLPVASSEEMKDGEELSPGRAIQRVKELVTTSSDTLFKAFSAFDRTGDGMIPQAEFRQVLDHFCMRLSDVQFKKLLSELRLNEGEELGVNWKEFLQVFNLHNEETADEWLKKISKMRFPNQTRPLAIGDILRRVQEVVSARIYTITKDMVDLDYANTNTISRSDFKTICDRHFMRLTEEQLQNLWKLLPVNDFGNLEYREFLKKFSGEQKGLDQAKSLPGSARSTVER----PASLRRPKTAPCSLRHSMSSVSEHVQRPSTASR-----RSAPLLNCEDVEMKVRPKIQDCWRHIQRRCRHADPEQTGEIDVDAFLGILQGLHIELSPSEFEQLTVKFDIKSNGRVSYPDFLRHFVLMFSPEVNSSSNRLRLQLPTTPMSPGPLSAQCVEAMLRISRPVQLFWRQMRQTFLSFDKERTGKISVQDFRKVLRQFSVNLSEEELFHFKSFFDKNLSGRISYNDFLRIFLK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : * .* . :* *. **. ::*: ** :*::.:* :*:..: *::: .*: :* . *:*.:::* * **:***:.**:.:***: :. *.*.*: ** *. :. :. * . . : :: : :: :*: :::.: :.*.::* *: * :: :***::** :*: : : ::. : .:*.:.. ::.*:.**::*.:. : : .. .: . : : . . .**::: * :: *.:. :****.* * ...*::*:: *: :*..* : : * :*::***:. : ::** ** . : .: * . : : : *:.** :: *::.** :. .. * :: ::: *: : *.*.:*. * : :* *..:. . ::*::. . : : . .: . * :::*::: : ::.* :.: : . :.. * ::*::::: . * *:: *: ::.. : : *. : ** * .:* . : : . : : ::*: : *:. . : :* *: .. .:. :. *:*: *: ::. *: :* .:**: :* **. :*: : : . :: . :::**:** : :::*: . * :**: * :***::. *:: *: * : : *::*:*.::** ..***: **:: :. :*: : . * . : **:*.*:** *:.* :::** * . .*: :.*: :..:*: *: :.:*:**.*** ** .**.*.:*.:* :*** :* * . .* : * . ::: :::*:: .:.:* :: ::.: ::: : .:*.. * *.* :: :*. ... . : : ::**: : . : : .:. * . :.* ..:: ::*:* :*. :* ****:*: . *:: ** :** .* :*:* *:: :* .**:: ::** **: *. . :****:* :::.* * .: : :*: *:::.*::: ::*.::: ::* ::**:**.:*::** *:. **:**::.**. :*** *.*:* :**.::* * : . .:* * . .:: :. : .:*.*. :.** **: :* ::* :**.***.: :.*:. * : * * . **.::: :::::* .* :** :*:*:*.**:.:* **:: **::..: .* .*:::* . . ..* :.. .*:***. : ** **::* ::*: ** :** ***.****:*:******:**. .::**.**.:******** **:", "identical_positions": 338, "similar_positions": 569, "identity": "21.85%" }, { "cls_id": "homologset.agr.RGD:1309066", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "F1LW54-1", "uniprot_id": "F1LW54_RAT", "id": "F1LW54-1", "name": "", "aln": "MVTVREALVHARITLLQVWWRVLLFSSVWPMTLCTEHKAPPETVIPVRVIVSSKEMSLTGWMSYSLHFGGHRHIISLKSKNFLVSRQLPVFTYSDQGVLFEDRPFVQTDCYYLGFVDEDPESMAALTTCFGGFQGILQINDTTYKIKPKTPSFTFEHLLYKIDSEETQLHPMRCGLTDEEIAGQVRLQENDKSTLMQSIYGSWWSHGLYIKLALVIDHEQFLYRKSNTSLVLKDVFNIMNGINLSLLSVDINVALLGLTIWTQRNPIPVQDIYTLLPAFCLWKTMNFNSQMAYDIAHLFVNYTFGDYFGIAFVGTVCNKTFGCGVDRLFGDNFLTIGHIVAHEIGHNLGMPHDGILCSCGEGPCLMSATMESSKKLSNCSYEFLWANIAKKS-CLQREPSSSDIFPMKICGNGVVDDGEECDCGSQSCGRNSRCCLPTCILKSGAKCASGLCCNFKCQIQPSGTLCRTKENECDLPEWCNGTSKECPEDTFVQAGTSCLGNGYCYEKRCNSHDDHCKRVFGEHAMKASDRCYKELNTRGDRFGNCGLKNKGYVRCETSDILCGRIQCAKVKTFPILESHYTVHWTRFNDASCWSTDYHLGMKIADLGDIKDGTNCGPQHVCISRKCVNKPSWKSDCSPETCNMRGICNNKQHCHCDFGWSPPLCVDNGTGGSIDSGSPAP-----------------------------------------------EDPNANKRKGIGK--FIILLLPIIFVVVVLFLLFYLFRTNRLSLGGDKQAKKGEEAKP-----------------PEEEA------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R160-1", "uniprot_id": "ADA24_MOUSE", "id": "Q9R160-1", "name": "Disintegrin and metalloproteinase domain-containing protein 24", "aln": "MVAMSEALVHARITLLQAWLRMLLFSSVWPPTWCAEYKGPPETVKPLRVIVSSKDMSLAGWMSYSLYFGGQRHIISMKSKNFLESRQLPVFTYNDQGVLFEDRPFVQNDCYYLGFVDGDLESMAALTTCFGGFQGILQINDTAYEIKPKSPSSTFEHLLYKIDSEKTQLRPMRCGLTDEEIAGQVRLQENGKSTRMQSIYGSWWSHGLYIKLALVIDHEQYLYRKKNTSLVIRDVLSIMQGINLFLLSVDINVVLLGLTIWTNGNPIPVQDIYALLPAFCTWKGTNLDSQIPYDIAHLFVNYTFSNYFGIAYVGTVCDKTFGCGIDSIAEDDFLTIGHIVAHEIGHNLGMSHDGILCTCGEESCLMSATMDSSQKLSNCSYEVLWAHMINKS-CIHREPRPSDIFQLKVCGNGIVEEGEQCDCGSSENCRRNRCCMPSCTLRSKAKCDTGLCCNRKCQIQPSGTLCRARENECDLPEWCNGTSHECPEDLFVQDGTSCPGDGYCYEKRCNSHDVHCQRVFGQLAMKASDSCYKELNTRGDRFGNCGFINNEYVRCEISDILCGRIQCDKVGTLPILQNHYTIHWTHFNSVSCWSTDYHLGMKIADLGDIKDGTNCGPQHVCIARKCVNKPSWVNDCTPETCNMKGVCNNKQHCHCDVGWSPPNCQETGTGGSIDSGSPGNE--------------------------------------------VYEDEVVSKKDAPEKPNVIIWLLPIICVAVVLSVLFCLSGATKKSREAAASQPAEERVKP-----------------PYEGAEPSYETVKPPDEWANP--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UKF5-1", "uniprot_id": "ADA29_HUMAN", "id": "Q9UKF5-1", "name": "Disintegrin and metalloproteinase domain-containing protein 29", "aln": "----------MKMLLLLHCLGVFLSCSGHIQDEHPQYHSPPDVVIPVRITGTTRGMTPPGWLSYILPFGGQKHIIHIKVKKLLFSKHLPVFTYTDQGAILEDQPFVQNNCYYHGYVEGDPESLVSLSTCFGGFQGILQINDFAYEIKPLAFSTTFEHLVYKMDSEEKQFSTMRSGFMQNEITCRMEFEEIDNSTQKQSSYVGWWIHFRIVEIVVVIDNYLYIRYERNDSKLLEDLYVIVNIVDSILDVIGVKVLLFGLEIWTNKNLIVVDDVRKSVHLYCKWKSENITPRMQHDTSHLFTTLGLRGLSGIGAFRGMCTPHRSCAIVTFMNKTLGTFSIAVAHHLGHNLGMNHDEDTCRCSQPRCIMHEGNPPITKFSNCSYGDFWEYTVERTKCLLETVHTKDIFNVKRCGNGVVEEGEECDCGPLKHCAKDPCCLSNCTLTDGSTCAFGLCC-KDCKFLPSGKVCRKEVNECDLPEWCNGTSHKCPDDFYVEDGIPCKERGYCYEKSCHDRNEQCRRIFGAGANTASETCYKELNTLGDRVGHCGIKNATYIKCNISDVQCGRIQCENVTEIPNMSDHTTVHWARFNDIMCWSTDYHLGMKGPDIGEVKDGTECGIDHICIHRHCVHITILNSNCSPAFCNKRGICNNKHHCHCNYLWDPPNCLIKGYGGSVDSGPPPKRKKKKKFCYLCILLLIVLFILLCCLYRLCKKSKPIKKQQDVQTPSAKEEEKIQRRPHELPPQSQPWVMPSQSQPPVTPSQSHPQVMPSQSQPPVTPSQSQPRVMPSQSQPPVMPSQSHPQLTPSQSQPPVTPSQRQPQLMPSQSQPPVTPS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: ** ::* .* .:::.**:.* *:*: ::: *: .**:** * ***::*** :* *::* *::******.***.::**:****.:*** *:*: * **:.:*:************** :*:*** : * *****:**:***:.*: .**.*: ::**: ::.::* .:** ** * .** * :::.:***: :: : * * ::.*: *:: :: * :.::* *:** ***: * * *:*: : :* ** *: .:: :* :***.. : . **. . :* .*.: : . : *:. ***.:****** ** * *.: *:* . *:***** :* ::: *: . ..*** :* ****:*::**:****. . .. **:..* * . :.* **** .*:: ***.:** . *************::**:* :*: * .* ****** *:.:: :*:*:** * .**: ******* ***.*:**: * *::*: **: ****** :* :* :..* *:**::**. *********** .*:*::****:** :*:** *:**: . .:*:* ** :*:****:****: *.** * .* ***:***.* *: .:: ::* * * .. * * : ", "identical_positions": 299, "similar_positions": 207, "identity": "35.98%" }, { "cls_id": "homologset.agr.RGD:1309067", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZCS5-1", "uniprot_id": "D3ZCS5_RAT", "id": "D3ZCS5-1", "name": "Structure-specific endonuclease subunit EME1", "aln": "MALRRLSLSLLSTESDSEELPTFAFLKKEPASTDSNPPQREKNIVVVT-SDIEASCPPSPGLKDPPCVPSAAEAPTQAGPVRVLSSSSEDEDGLVSLAERITWKLLRNKQLSPERSRSPLKTGSDHQKNASTPCDWKRQPCPKIPDVPLHSALEKSPANDKDSLLDNQCHQLPAYQATGR----ELAVTKTNPDLPLPKKRTKHIQTAQSRGPQGCWQPRQASRKENTPRQQERKKKAEMVNRLRAQRPEECLKHIVVVLDPVLLQMEGGGQLLGALQAMECSCVIEAQVVPQSITWRR-KTELEEDGDDWVEEPTILVLVLKEVFMSMVYNSKQGNPGSTEKGKETLRGFVTDVTARTG-KALSLVIVDQEKCLRAQNPPKRRKSGMANKKAKEKHQQRRESSTRLMVSRVDMEEALVDLQLYTEAQARIVQS--WRELADFACAFTKAVAEAPFKKLRDQGS--FSFFLEKDWAGGVKADHAGRGLALIWRRQIQQLNRVSSEMAGAIVDAYPSPQLLVQAYQQCFSEQERQNLLANIQVRRGEG--VTATSRRVGPELSRRIYLQMTTVQPDLILDSVD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BJW7-1", "uniprot_id": "EME1_MOUSE", "id": "Q8BJW7-1", "name": "Structure-specific endonuclease subunit EME1", "aln": "MALRRLSLSRLSTESDSEDLPTFAFLKKEPSSTNRKPPQRAKNIVVVT-SDSEASCPPSPGLKGPPCVPSAAGAPPQAGPVRVLSSSSEDEDVFVPLAERITCKLLTSKQLCPELSSSSLKTGLDGQNNASAPCDWKRQPWPKIPDVPLHGALEKSAANDEDSLLDDQCRQLPTYQATCR----ELAVSKTNSDRPLPKKRTKHIQTVQSGGSQGCWRPGQASRKENTPRQHERKKKAEMIKRLKAQRPEECLKHIVVVLDPVLLQMEGGGQLLGALQAMECSCVIEVQAIPRSITWRRRRTELVEDGDDWMEEPTILVLVLAEVFMSMAYNLKQASPSSTEKGKETLRSFVTDVTAKTG-KALSLVIVDQEKCFRPQNPPRRRKSGMANKQAKAKHQQRQESSTGLMVSRADMEKALVDLQLYTEAQAWMVQS--WKELADFTCAFTKAVAEAPFKKLRDQVT--FSFFLEKDWAGGMKVDQSGRGLALIWRRQIQQLNRVSSEMASAIVDAYPSPQLLVQAYQRCFSEQERQNLLADIQVRRGEG--VTATSRRVGPELSRRIYLQMTTAQPDLILDSVD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96AY2-1", "uniprot_id": "EME1_HUMAN", "id": "Q96AY2-1", "name": "Structure-specific endonuclease subunit EME1", "aln": "MALKKSSPSLDSGDSDSEELPTFAFLKKEPSSTKRRQPEREEKIVVVDISDCEASCPPAPELFSPP-VPEIAETVTQTQPVRLLSSESEDEEEFIPLAQRLTCKFLTHKQLSPEDSSSPVKSVLDHQNNEGASCDWKK-PFPKIPEVPLHDTPERSAADNKDLILD-PCCQLPAYLSTCPGQSSSLAVTKTNSDILPPQKKTKPSQKVQGRGSHGCRQQRQARQKESTLRRQERKN-AALVTRMKAQRPEECLKHIIVVLDPVLLQMEGGGQLLGALQTMECRCVIEAQAVPCSVTWRR-RAGPSEDREDWVEEPTVLVLLRAEAFVSMIDNGKQGSLDSTMKGKETLQGFVTDITAKTAGKALSLVIVDQEKCFSAQNPPRRGKQG-ANKQTKKQQQRQPEASIGSMVSRVDAEEALVDLQLHTEAQAQIVQS--WKELADFTCAFTKAVAEAPFKKLRDETT--FSFCLESDWAGGVKVDLAGRGLALVWRRQIQQLNRVSLEMASAVVNAYPSPQLLVQAYQQCFSDKERQNLLADIQVRRGEG--VTSTSRRIGPELSRRIYLQMTTLQPHLSLDSAD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1Z8C0-1", "uniprot_id": "A1Z8C0_DROME", "id": "A1Z8C0-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSNKVDKLHKQALREQQKRIKPGECMKYVRMVIDAGFLGIPVGQEALQQLNATGLKYEIRSLPVSHCILWER-----------------------NVGQQTIALGSSPTGLDEAWKSENQVVQWLSESSFQRAVKDQSLVCLG-----------PRLQDSFPDCQYTIALPTLRHSKHGSSSS----QDALIEMQLLQELHVEQLDQPESQDLVALLQRYTKAIAEAPYKKQRNETLGGFKKYLANDKKQCVRVDQ-GNGYGRLWQQHLNRLPMVTLEVAESIIAQYPCPKKLIDHFS---SDPLAVQSLADLKIKRCNGPQPLHTERRIGNVLSNKLYTLYTAKDPNTLI----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: :: : : : : :* **:*:: :*:*. :* : * : * *:: *. :. .: *.* :: . . . ..: *.:: : :::: : : . * *** :. * :.. .: : . .:. * :.**:::** * :. ::. ::*. : :***:****:** *:: *. * .* ::.* *.* . :*::::::* *: *:* ::: **.*: *:: :. *: : **:::::* :* *.**:* **.::* *: :*. : ", "identical_positions": 65, "similar_positions": 118, "identity": "11.17%" }, { "cls_id": "homologset.agr.RGD:1309068", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "B0K017-1", "uniprot_id": "B0K017_RAT", "id": "B0K017-1", "name": "ADP-ribosylhydrolase ARH3", "aln": "MAAAAAAAAAAMTAAGGGGAGAARSLSRFRGCLAGALLGDCVGAVFEAHDTVSLTSVLSHVQSLEPDPGTPGSARTETLYYTDDTAMTRAMVQSLLAKEAFDEVDMAHRFAQEYKKDPDRGYGAGVITVFKKLLNPKCRDVYEPARAQFNGKGSYGNGGAMRVAGIPLAYHSVQDVQKFARLSAQLTHASSLGYNGAILQALAVHLALQGVSSS-EHFLEQLLGHMEELEGDAQSVLDAKELGMEERPYSSRLKKVGELLDQDAVSREEVVSELGNGIAAFESVPTAIYCFLRCMEPDPEIPSTFNSLQRTLIYSISLGGDTDTIATMAGAIAGAYYGVEQVPESWQQSCEGYEETDVLAQSLHRVFQESP----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CG72-1", "uniprot_id": "ADPRS_MOUSE", "id": "Q8CG72-1", "name": "ADP-ribosylhydrolase ARH3", "aln": "MAVAAAAAATAMSAAGGGGASAARSISRFRGCLAGALLGDCVGAVYEAHDTVSLASVLSHVESLEPDPGTPGSARTETLYYTDDTAMTRALVQSLLAKEAFDEVDMAHRFAQEYKKDPDRGYGAGVITVFKKLLNPKCRDVYEPARAQFNGKGSYGNGGAMRVAGISLAYSSVQDVQKFARLSAQLTHASSLGYNGAILQALAVHLALQGVSSS-EHFLEQLLGHMEELEGDAQSVLDAKELGMEERPYSSRLKKVGELLDQDVVSREEVVSELGNGIAAFESVPTAIYCFLRCMEPHPEIPSTFNSLQRTLIYSISLGGDTDTIATMAGAIAGAYYGMEQVPESWQQSCEGFEETDVLAQSLHRVFQESS----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NX46-1", "uniprot_id": "ADPRS_HUMAN", "id": "Q9NX46-1", "name": "ADP-ribosylhydrolase ARH3", "aln": "------MAAAAMAAAAGGGAGAARSLSRFRGCLAGALLGDCVGSFYEAHDTVDLTSVLRHVQSLEPDPGTPGSERTEALYYTDDTAMARALVQSLLAKEAFDEVDMAHRFAQEYKKDPDRGYGAGVVTVFKKLLNPKCRDVFEPARAQFNGKGSYGNGGAMRVAGISLAYSSVQDVQKFARLSAQLTHASSLGYNGAILQALAVHLALQGESSS-EHFLKQLLGHMEDLEGDAQSVLDARELGMEERPYSSRLKKIGELLDQASVTREEVVSELGNGIAAFESVPTAIYCFLRCMEPDPEIPSAFNSLQRTLIYSISLGGDTDTIATMAGAIAGAYYGMDQVPESWQQSCEGYEETDILAQSLHRVFQKS-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q66HT8-1", "uniprot_id": "ADPRS_DANRE", "id": "Q66HT8-1", "name": "ADP-ribosylhydrolase ARH3", "aln": "------MSAAARVVAP------VMMLSRFRGALVGSVLGDCIGGEFEGAVDVPLDRVLQHLSALEDDTRGDG-----ILQYSDDTAMMRCVADSLLTRMTFDERDMAQRFAKEYSHSPGRGYGSGVVQVLRKLASPHLKDVFQPAQAQFGGRGSFGNGGAMRAVPFALAFRSRADVRKYSRFGAMLTHSCSLGYNGAALQALAVHLSLQGALALPKDFIDKLISEMEELEKDETAKHDAKALNLSEFPYCSRLHRVKELMDKTSVSIEEVISELGNGIAALQSVPTAIFCVLYCLEPQDGLPERFGGLERTIAYSLALGGDTDTIACMAGAIAGAHYGIDSIPLSWQVSCEGVDEADDLARRLYDLYCLPQHNEDRGNNQPHTTNTD", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*:* .* . :*****.*.*::****:*. :*. * * ** *:.:** *. * * *:***** *.:.:***:: :*** ***:***:**.:.*.****:**: *::** .*: :**::**:***.*:**:*******.. :.**: * **:*::*:.* ***:.******* ********:*** : :.*:.:*:..**:** * : **: *.:.* **.***::: **:*: *: ***:*********::******:*.* *:**. :*. *..*:**: **::********* ********:**::.:* *** **** :*:* **: *: :: . ", "identical_positions": 186, "similar_positions": 106, "identity": "48.06%" }, { "cls_id": "homologset.agr.RGD:1309069", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z9D2-1", "uniprot_id": "D3Z9D2_RAT", "id": "D3Z9D2-1", "name": "FYVE and coiled-coil domain-containing protein 1", "aln": "MASSSTETQLQRIIRDLQDAVTELSNEFKEGGEPITDDSTSLHKFSYKLEYLLQFDQKEKASLLGSKKDYWDYFCACLAKVKGANDGIRFVRSISELRTSLGKGRAFIRYSLVHQRLADTLQQCFMNTKVTSDWYYARSPFLKPKLSSDIVGQLYELTEVQFDLASRGYDLDAAWPTFARRTLATS-SSYMWKPPSRSSSMSSLVSNY-LQTQEMASSLDLNSSLNNEALES-------FDEMRLELDQLEVREKQLQEHVQQLNRENQALRMTISKQGGQLQVEKETGYLAVEDSIDLVSLVAELQKQGEVTQAT---VKKLQTCLQALELAVDQKE-TSHSVLQ-----LENVAQALDAVRDSLGRKNQLLASLSECLTRAEKREHPSLDTKLHQEPVPTDLALKFQELKGKLQTLEGENTKAQELNRQQSLKLEQLAKELQLKEEARASLEH-LVKDAVPLQEELSGKKQESAQLRRQLQESLAHLSSVEEELAEARQQEKQHREEKQLLEQEAKSLTWQLQLLETQLGQVSQLVSDLEEQKKQLMQDKDHLSQKVGTLEQLAEAHGASKSKE-----------AVPPQAGEMPEKGQHCLQEEQVNNATVRGADQDE-LQKVNQELQKELQNMAVRNQLLEGKLQALQTDYKALQQREAAIQGSLASLEAEQASIRQLGNQMEASLLAVRKAKETMKAQVAEKEAALQSKEGECRQLQEEAEQCRLRTEAQAQELRALENQCQQQIQLIEVLSAEKGQQGLSLPQVNTA-----QLALSQAQLEIHQGEAQRLQNEVVDLQAKLQVALGDRDKLQSQLGVAEAVLGEHKTLVQQLKEQNEALNRAHIQELLQCSEREGILQEESIYKAQKQ---EQELRALQAELSQVRCSSEGAHLEHAELQDQLHRANTDTAELGIQVCALTAEKDRMEGALASLAQELQDSKEAALQERKGLELQVMQLQQEKESLQEKLKATEEAASSFSVLQAQLAQAEQLAQSLQEAAHQEQDALKFQLSAEIMDHQNRLKTANEECGSLRAQLEEQGQELQMTKEAVQELKITKATMEEKLNCTGSHLAECQATLLRKDEESAMLRINLERTQKELEKATSKFQEYYNKLCQEVTNRERNDQKMLADLDDLNRTKKYLEERLIELLRDKDALWQKSDALEFQQKLSAEEKCLGDMEANHCHDCKREFSWIVRRHHCRLCGRIFCYYCCNNYVVTKPSGKKERCCRACFQKFGESSGSPDSSGSGTSQGEPSPMVSPAEAAPQSIGSQGINPVCRPP--DDAVFDIITDEELCQIQESGSSLPETPTETDSMDPNMAEQDTTSNSLTPEDTEDMPLGQDAEICLLKSGELMIKLPLTVEEIASFGEGNRELFVRSSTYSLIPITVAEPGLTISWVFSSDPKSISFSVVFQETEDTPLDQCKVLIPTTRCNSHKESIRGQLKVRTPGIYLLIFDNTFSRFISKKVFYHLTVDRPVIY----DGSDFP---------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VDC1-1", "uniprot_id": "FYCO1_MOUSE", "id": "Q8VDC1-1", "name": "FYVE and coiled-coil domain-containing protein 1", "aln": "MASSSTETQLQRIIRDLQDAATELSHEFKEGGEPITDDSTSLHKFSYKLEYLLQFDQKEKASLLGSKKDYWDYFCACLAKVKGANDGIRFVRSISELRTSLGKGRAFIRYSLVHQRLADTLQQCFMNTKVTSDWYYARSPFLKPKLSSDIVGQLYELTEVQFDLAPRGYDLDAAWPTFARRTLATSTSAYMWKPPSRSSSMSSLVSNY-LQTQEMASSLDLNCSLNNEALES-------FDEMRLELDQLEVREKQLQERVQQLDRENQALRMLVSRQGGQLQVEKEMGYLAVEDSIGLVSLVAELQKQGDVSQAT---VKKLQSCLQALELNVDKKE-YSPSALQ-----LENMAKELDTVRGSLGRENQLLASLSERLARAEKGEKTPPDTELHQEPVPADLVLKFQELKGKLQALEGENTEAQELNRQQSIKLEQLAKELQLKEEARASLAH-LVKDVVPLQEELSGKKQESAQLRRQLQESLAHLSSVEEELAEARQQEKQHREEKQLLEQEATSLTWQLQLLETQLGQVSQLVSDLEEQKKQLMQERDHLSQRVGTLEQLAEVHG-------------------PPQSAEMPEKRQQCLREEQVNNSTVSEAEQE--------ELQKELQNMVDRNQLLEGKLQALQTDYKALQQREAAIQGSLASLEAEQASIRHLGNQMEASLLAVKKAKETMKAQVAEKEAALQSKESECQRLQEEADQCRLQAEAQAQELRALENQCQQQIQLIEVLSAEKGQQGLSLPQVNTD-----QLALSQAQLEIHQGEAQRLQNEVVDLQAKLQVALGDRDKLQSQLGVAETVLREHKTLVQQLKEQNEALNRAHVQELLQCSEREGILQEESIYKAQKQ---EQELRALQAELSQVRCSSEGAHLEHAELQDQLHRANTDTAELGIQVCALTAEKDRMEEALASLAQELQDSKEAALQERKGLELQVMQLQQEKEKLQEKVKAAEEAASSFSGLQAQLAQAEQLAQSLQETAHQEQDALKFQLSAEIMDHQNRLKTANEECGHLRAQLEEQGQQLQMTKEAVQELEITKAAMEEKLNCTSSHLAECQATLLRKDEESTMLQTSLERTQKELEKATSKIQEYYNKLCQEVTNRERNDQKMLADLDDLNRTKKYLEERLIELLRDKDALWQKSDALEFQQKLSAEEKCLGDMEVNHCHDCKREFSWIVRRHHCRICGRIFCYYCCNNYVVTKPSGKKERCCRACFQKFGEGSGSNDSSGSGTSQGEPSPMVSPAEASPQSIGSQGINSVCRPP--DDAVFDIITDEELCQIQESGSSLPETPTETDSMDPNTAEQDTTSNSLTPEDTEDVPMGQDAEICLLKSGELMIKLPLTVEEVASFGEGSRELFVRSSTYSLITITVAEPGLTISWVFSSDPKSISFSVVFQETEDTPLDQCKVLIPTTRCNSHKENIRGQLKVRIPGIYLLIFDNTFSRFISKKVLYHLTVDRPVIY----DGSDFP---------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BQS8-1", "uniprot_id": "FYCO1_HUMAN", "id": "Q9BQS8-1", "name": "FYVE and coiled-coil domain-containing protein 1", "aln": "MASTNAESQLQRIIRDLQDAVTELSKEFQEAGEPITDDSTSLHKFSYKLEYLLQFDQKEKATLLGNKKDYWDYFCACLAKVKGANDGIRFVKSISELRTSLGKGRAFIRYSLVHQRLADTLQQCFMNTKVTSDWYYARSPFLQPKLSSDIVGQLYELTEVQFDLASRGFDLDAAWPTFARRTLTTGSSAYLWKPPSRSSSMSSLVSSY-LQTQEMVSNFDLNSPLNNEALEG-------FDEMRLELDQLEVREKQLRERMQQLDRENQELRAAVSQQGEQLQTERERGRTAAEDNVRLTCLVAELQKQWEVTQATQNTVKELQTCLQGLELGAAEKEEDYHTALRRLESMLQPLAQELEATRDSLDKKNQHLASFPGWLAMAQQKADTASDTKGRQEPIPSDAAQEMQELGEKLQALERERTKVEEVNRQQSAQLEQLVKELQLKEDARASLER-LVKEMAPLQEELSGKGQEADQLWRRLQELLAHTSSWEEELAELRREKKQQQEEKELLEQEVRSLTRQLQFLETQLAQVSQHVSDLEEQKKQLIQDKDHLSQQVGMLERLAGPPGPELPVAGEKNEALVPVNSSLQEAWGKPEEEQRGLQEAQLDDTKVQEGSQEEELRQANRELEKELQNVVGRNQLLEGKLQALQADYQALQQRESAIQGSLASLEAEQASIRHLGDQMEASLLAVRKAKEAMKAQMAEKEAILQSKEGECQQLREEVEQCQQLAEARHRELRALESQCQQQTQLIEVLTAEKGQQGVGPPTDNEARELAAQLALSQAQLEVHQGEVQRLQAQVVDLQAKMRAALDDQDKVQSQLSMAEAVLREHKTLVQQLKEQNEALNRAHVQELLQCSEREGALQEERADEAQQR---EEELRALQEELSQAKCSSEEAQLEHAELQEQLHRANTDTAELGIQVCALTVEKERVEEALACAVQELQDAKEAASREREGLERQVAGLQQEKESLQEKLKAAKAAAGSLPGLQAQLAQAEQRAQSLQEAAHQELNTLKFQLSAEIMDYQSRLKNAGEECKSLRGQLEEQGRQLQAAEEAVEKLKATQADMGEKLSCTSNHLAECQAAMLRKDKEGAALREDLERTQKELEKATTKIQEYYNKLCQEVTNRERNDQKMLADLDDLNRTKKYLEERLIELLRDKDALWQKSDALEFQQKLSAEERWLGDTEANHCLDCKREFSWMVRRHHCRICGRIFCYYCCNNYVLSKHGGKKERCCRACFQKLSEGPGSPDSSGSGTSQGEPSPALSPASPGPQATGGQGANTDYRPP--DDAVFDIITDEELCQIQESGSSLPETPTETDSLDPNAAEQDTTSTSLTPEDTEDMPVGQDSEICLLKSGELMIKVPLTVDEIASFGEGSRELFVRSSTYSLIPITVAEAGLTISWVFSSDPKSISFSVVFQEAEDTPLDQCKVLIPTTRCNSHKENIQGQLKVRTPGIYMLIFDNTFSRFVSKKVFYHLTVDRPVIY----DGSDFL---------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HXM1-1", "uniprot_id": "A0AC58HXM1_DANRE", "id": "A0AC58HXM1-1", "name": "", "aln": "-MSTVGENQLQRIIRDLHDAVSELSKEHCDTEDPITDDSSSLHKFCFKLEYLLQFDQKERTTFLGSRKDYWDYFCDCLAKIKGANDGIRFVKSIPELKTSLGKGRAFIRYCLVHQRLADTLQQCLINLKITSEWYYERSPFLKSHLNIDIINHLYELNEVQFDVASRGYDLDSQWPTFARRTLGSAVSPHVWKPPSRCSSVNSLVSSYTQQVQDFLPGQDFGSSLLGDLGELGELTCSTSEDLRIELDQSELKQQQLKEKIQLLTDEAADLRVVIKDLQEQLLAKGSDQEKAGEQQQEVVKAVRECADLLSTTTQG---LEALRTSERNLEAKLSVAE----------------------------NRNMELLAKLDGALS-----------EKGQQAANYCDSAWTIQELLTKLKEAEQERIEAKRESEDRARIAERLSQEIKLQEGKLKEMEGNLDMCRVTADKERTTATQQADELQMTINRLQGALSLKERETGNLR---TQLQDVQKALEAQQDQMEEHMKKIQEEMQRKSVLEEQLNAKMNELSVNTQKMRQLENHNQRLIVENQ-----------------SFQAQAKKLEEYKSQCTSLMEINAKLIQTVKRNE-------DSSKELSEIKTT---LEKELKTLQASERQLRTR------------LESAGLTVESQNLEECIENGQTDNEDVLEKLNESTTAPQKNKRTTSGLLQEANECSKTDHVESTTR----------------------------------------LALAEAQLELNMKEVSRLQDEVLELRAQLLVISEERMKIQALQEVTEASREDLRAQTEQLKSQVEELNRRHVEELLRCHEREETLGKERDMEAKMRAEIQTSMTSMKEECHALKKHNSTLALENGEAREALHRANTETAELGVHVCMLTGQNEEAKLRWEELSNKLQELQMEAQEEVKTLSDSMESLRKDNAGLKEQVKQMEGLQEALQKLQEKLERAEDEARSLQEIRQREVDTLRSQLSDEAAHHQSQVQGMSEDMDALRKRLDIEVEKVSSLEAKVLKLESLNSGQSQMIEKTTALIGDSETIIYQKEEQIKNLKVDLSRAEKELVLAQQSCQELGVNLSRSAMEKQAVELKMSAELDDLYRTKKNLEERLIELIREKDALWQKSDALEFEQKRRAEEQT--DRDVTHCLSCKSQFSWMLRRYNCRFCGRPFCYSCCS-------FGGKDRCCKSC---------STHSERQQADQGSPSHSTYSPISSPNQTSTPGVPWILKSPRPDDMAYDIITEDEVNRVHDS-----DSSSYTTALSPETQQLSSSDVTSTEDSDELIGSVQDSEICLLKSGERTLSVPFSVDDVMHFGSKSKELFIKSSCYSVILISAAHPGPSIGWTFSSEPKSIAFSVVYRETTDTPLEQAKVLIPLTRCRSHKETIQGQLKVRNPGQYTLIFDNSFSRFVSKKVQYKLSIEMPEVTGLLVQGYGCLKAKYVMLLSELTNSSWRNVEVDVLWLPQRLSFSSVLKIEIQKRITEKACKVGHIDSSTVIVVNSSMRLKSFDVHGELLVKLVTVGKPSTWREEKNLYRFGTKFGLKPYCRLLSVSQVHRRTSRANWTNW", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: *.*********:**.:***:*. : :******:*****.:************::::**.:******** ****:**********:**.**:************.*************::* *:**:*** *****:.:*. **:.:****.*****:*.**:***: ********* :. *.::******.**:.****.* *.*:: .. *:...* .: * :::*:**** *::::**:*::* * * ** :. ** .: . * *:. :. * * . ..: :: *::. : ** * .:: : **.: *: : :* . * . :*** **: * *. :.:. ..::: *:* :*::*:* .: * .. ::* : *:: :* ::. . * *.* .: * .* :: :: ** : .: ::: :: :: : * .:*: : ::* : ::: * . ::* :: * .: ::: : .:: : .***.:: ** :*::**:. : *: * *.*.: .:::* .: :. :* : :: *. : *.:: * :*.::* ... ***::****:: *..*** :*::*:*:: . :: *:*: ::*: : :: .:***.* * *** *::***:* *** * :* :*: : : .: ::: * : .. **:.* :: ******:*****::** ** :::. : ::**: : * .* : *. .: *:::: *:*::* : :: ** :* :**: *:**** ::* ::*: *** * .:*.::: .*: ** :*: : .::. : * :*: :: : :. * :.:.:: : :*::: *: .*.*::*** * . ** :*.:.. ::: : ** *:**** **** ********:*:*************:** ***: * :..** .** :***::**::**:*** *** **. * *:***::* * .*. . :.**.** .. ..*: . * :.* ** .:****::*: ::::* ::.: * ::.*: : .::. : * :. * : **:********* :.:*::*::: **. .:***::** **:* *:.*..* :*.*.***:****:****::*: ****:*.***** ***.****.*:****** ** * *****:****:**** *:*::: * : :* . ", "identical_positions": 496, "similar_positions": 444, "identity": "30.52%" }, { "cls_id": "homologset.agr.RGD:1309070", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P16675-1", "uniprot_id": "PPGB_MOUSE", "id": "P16675-1", "name": "Lysosomal protective protein", "aln": "----------------------------------------------MPGTALSPLLLLLLLSWASRNEAAP--------------------------------------DQDEIDCLPGLAKQPSFRQYSGYLRASD-SKHFHYWFVESQNDPKNSPVVLWLNGGPGCSSLDGLLTEHGPFLIQPDGVTLEYNPYAWNLIANVLYIESPAGVGFSYSDDKMYVTNDTEVAENNYEALKDFFRLFPEYKDN--KLFLTGESYAGIYIPTLAVLVMQDP---SMNLQGLAVGNGLASYEQNDNSLVYFAYYHGLLGNRLWTSLQTHCCAQNKCNFYDNKDPECVNNLLEVSRIVGKSGLNIYNLYAPCAGGVPGRHRYE-DTLVVQDFGNIFTRLPLKRRFPEALMR-SGDKVRLDPPCTNTTAPSNYLNNPYVRKALHIPESLPRWDMCNFLVNLQYRRLYQSMNSQYLKLLSSQKYQILLYNGDVDMACNFMGDEWFVDSLNQKMEVQRRPWLVDYGESGE--QVAGFVKECSHITFLTIKGAGHMVPTDKPRAAFTMFSRFLNKEPY-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6ARV9-1", "uniprot_id": "A0A8I6ARV9_RAT", "id": "A0A8I6ARV9-1", "name": "Carboxypeptidase", "aln": "----------------------------MPGLVGSDRVSVAGSWTGMPRAALSPLLLLLLLSWASRDEAAP--------------------------------------DQDEIDCLPGLAKQPSFRQYSGYLKASD-SKHFHYWFVESQNDPKNSPVVLWLNGGPGCSSLDGLLTEHGPFLIQPDGVTLEYNPYSWNLIANMLYIESPAGVGFSYSDDKMYVTNDTEVAENNYQALKDFYHLFPEYKDN--KLFLTGESYAGIYIPTLAVLVMQDP---SMNLQGLAVGNGLSSYEQNDNSLVYFAYYHGLLGNRLWTSLQTHCCSQNKCNFYDNKDPDCVNNLQEVSRIVGKSGLNIYNLYAPCAGGVPGRDRSE-DTLVVQDFGNIFTRLPLKRRFPEALLLRSGDKVRLDPPCTNTTAPSTYLNNPYVRKALHIPESLPRWDMCNLMVNLQYRRLYESMNSQYLKLLSSQKYQILLYNGDVDMACNFMGDEWFVDSLNQKMEVQRRPWLVDYGESGE--QVAGFVKECSHITFLTIKGAGHMVPTDKPRAAFTMFSRFLNKEPY-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P10619-1", "uniprot_id": "PPGB_HUMAN", "id": "P10619-1", "name": "Lysosomal protective protein", "aln": "-----------------------------------------MIRAAPPPLFLLLLLLLLLVSWASRGEAAP--------------------------------------DQDEIQRLPGLAKQPSFRQYSGYLKGSG-SKHLHYWFVESQKDPENSPVVLWLNGGPGCSSLDGLLTEHGPFLVQPDGVTLEYNPYSWNLIANVLYLESPAGVGFSYSDDKFYATNDTEVAQSNFEALQDFFRLFPEYKNN--KLFLTGESYAGIYIPTLAVLVMQDP---SMNLQGLAVGNGLSSYEQNDNSLVYFAYYHGLLGNRLWSSLQTHCCSQNKCNFYDNKDLECVTNLQEVARIVGNSGLNIYNLYAPCAGGVPSHFRYEKDTVVVQDLGNIFTRLPLKRMWHQALLR-SGDKVRMDPPCTNTTAASTYLNNPYVRKALNIPEQLPQWDMCNFLVNLQYRRLYRSMNSQYLKLLSSQKYQILLYNGDVDMACNFMGDEWFVDSLNQKMEVQRRPWLVKYGDSGE--QIAGFVKEFSHIAFLTIKGAGHMVPTDKPLAAFTMFSRFLNKQPY-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P00729-1", "uniprot_id": "CBPY_YEAST", "id": "P00729-1", "name": "Carboxypeptidase Y", "aln": "MKAFTSLLCGLGLSTTLAKAISLQRPLGLDKDVLLQAAEKFG-LDLDLDHLLKELDSNVLDAWAQIEHLYPNQVMSLETSTKPKFPEAIKTKKDWDFVVKNDAIENYQLRVNKIKDPKILGIDPNVTQYTGYLDVEDEDKHFFFWTFESRNDPAKDPVILWLNGGPGCSSLTGLFFELGPSSIGPD-LKPIGNPYSWNSNATVIFLDQPVNVGFSYS-GSSGVSNTVAAGKDVYNFLELFFDQFPEYVNKGQDFHIAGESYAGHYIPVFASEILSHK-DRNFNLTSVLIGNGLT------DPLTQYNYYEPMACG---EGGEPSVLPSEECSAMEDSLERCLGLIESCYDSQSVWSCVPATIYCNNAQLAP----YQRTGRNVYDIR-----------------KDCEGG---NLCYPTLQDIDDYLNQDYVKEAVGAEVDHYESCNFDINRNFLFAGDWMKPYHTAVTDLLNQDLPILVYAGDKDFICNWLGNKAWTDVLPWKYDEEFASQKVRNWTASITDEVAGEVKSYKHFTYLRVFNGGHMVPFDVPENALSMVNEWIHGGFSL----------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P38109-1", "uniprot_id": "ATG42_YEAST", "id": "P38109-1", "name": "Vacuolar serine-type carboxypeptidase ATG42", "aln": "MKYLN-------LVFVLQLLISIKYASFGRAFSLFEDDTTFANLDKQLKLPQNTQQTLKLDRLNHDDPLFTTFISSVDT--------------------------DYSLRLRTV-DPSKLGIDT-VKQWSGYMDYKD-SKHFFYWFFESRNDPANDPIILWLNGGPGCSSFTGLLFELGPSSIGAD-MKPIHNPYSWNNNASMIFLEQPLGVGFSY--GDEKVSSTKLAGKDAYIFLELFFEAFPHLRSN--DFHIAGESYAGHYIPQIAHEIVVKNPERTFNLTSVMIGNGIT------DPLIQADYYEPMACG---KGGYHPVLSSEECEKMSKAAGRCRRLNKLCYASKSSLPCIVATAYCDSALLEP----YINTGLNVYDIR-----------------GPCEDNSTDGMCYTGLRYVDQYMNFPEVQETLGSDVHNYSGCDNDVFTGFLFTGDGSKPFQQYIAELLNHNIPVLIYAGDKDYICNWLGNHAWSNELEWINKRRYQRRMLRPWVSKETGEELGQVKNYGPFTFLRIYDAGHMVPYDQPEASLEMVNSWISGNRAFSDLSTLENAS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . : *. :. . *::**: .. .**:.:* .**::** :.*::***********: **: * ** : .* :. ***:** *.:::::.* .***** .. .:. ..:. : *: *: **. .: .:.::****** *** :* :: . .:** .: :***:: :.* **. : . . ..::*. .. * . . *. * * * *: . . . . . *:* *:::: :. .: : . : * .:. :*:* ** * **::*:. : : * . . : : : * **. :::* : ..***** * * :: *.. :: ", "identical_positions": 96, "similar_positions": 131, "identity": "16.58%" }, { "cls_id": "homologset.agr.RGD:1309071", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q7T019-1", "uniprot_id": "DZIP1_DANRE", "id": "Q7T019-1", "name": "Cilium assembly protein DZIP1", "aln": "MPFYDNVYYPYPSDPPGTHSSAGIPSLLSSPQSQPSSGSQSRPAPSTMSGPLTSSGASTSIPPPFKFRSRRENVDWRRINAVDVDRVACEMDFQALQEHINAVTFCSVEGERCHRCQSPVDPALIKLFRLAQLTVEYLLHSQDCLSISLQAAEERLLAEAREREQICVQLQKKTQDAKALKEELKQRKKIIASQQAMFSAGISANYHKCQHCEKAFMNASFLQSHMQRRHPSEFDMKLMTDNQKKIQTVKLQDEINKLQEQLTLVTSQMETQQKDYTAKQEKELIQR---QEEFKRQLEIWKEEEKMRMNSKIDEVKQACQRDMDSINQRNRNLETELLKLQQKNIQESMQSVQTQPNASTSNEHWQEVVKLQQKLHKQEVKWTGKMQKMKEDHDREKSLLQEELCKVSSAVSEGMEESRRQVQELSHRLQEQQQIITSQNKQMKQISSKPPTITVQREGVSTPSPETKAKVVVSEQSNSVHKLDPIVELSEEDKDSSSISESPTENRSWQKEVQELLKNPGLRRDMRLAAQHNLDDRLQSLGIKGVSGLSKNLYKSSMTQIISDRRKKLEEDPVYRRALKEISHKLEQRVKERNTEQPVKSKLHEQVVQSRPRSSSFPSTVTRVMSGPASKQQRTPQPVPRSRTNVPHKTSTPLQHRRTPPFSSDEDSSEEEEEEEEEEESSDEESPQMQKKTVLVNSSTAKAQNTAKTQSTAQSVRSAVALTSAEPTNVTTLSDSDWTDGSEMEEINLSQLHKHTDQNGNLKNVTHSNVKALGKSLEKQLAARGPKKPAGGVNTFLEKPTDVRNTRQNAKKELKYSDDDDDDDDDWDISSLEDVPAVAKPTQCPVPVRKSLDKSQDTSTSVWGSSTGKGHKPGLTDAGTASTLKSSLVTVSDWDDSDEI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M0R431-1", "uniprot_id": "M0R431_RAT", "id": "M0R431-1", "name": "", "aln": "MPFQKHICYPQSN----------------------SQKNRVAPEGGATPRACVTSTSASGPLPFFQFRPRLENMNWRRLDTIDVDKVVGTMDILTLQENIMNITFCKLEGEKCPYCQAEVDPLLLKLIRLAQLTIEYLVQSQEFLTSQLSMVEDRLRLSLSGFEQNKQLLAKQAEDIRLLKQECRRRKKMLSAQQLMMGQ-VQAGHYQCGFCDKAFMSQASLQSHLHRRHA---AVDSCSGKKAMARNDKLQEEVTMLKEQLQVTRTQLESVQHTHRVRPSTDYERQKINEEDFQKLVVSWEEEEKQTLVNEMEKVKDMLRKEFEELTLKNSSLEYQLLEIQKSNVQSEVNMGREKLP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** .:: ** .. *. .: * .: . . .:* :::. * *:**.* **::***::::***:*. **: :***:* :***.:***:* **: *** *:**:******:***::**: *: .*. .*:** . ** * *:::* : **:* ::***::::** *:. :.*.:::* .*:****. : ****::***. :. :.:: :. ***:*:. *:*** :. :*:*: *: : .: ..: :: :*:*:: : *:**** : .::::**: :::::.:. :* .** :**::*:.*:*..:: : : ", "identical_positions": 115, "similar_positions": 135, "identity": "12.76%" }, { "cls_id": "homologset.agr.RGD:1309072", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZR96-1", "uniprot_id": "D3ZR96_RAT", "id": "D3ZR96-1", "name": "", "aln": "MLDMSEARAQPPCSPSGTASSMSHVEDSDSDAPPSPAGSEGLGRAG---GGGRGDTAEAADERFPACIRDAVSQVLKGYDWSLVPMPVRGGGGGTLKAKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEEAERLRVQHKKDHPDYKYQPRRRKS-VKTGRSDSDSG---------------------------------------------TELGHHPGG-PMYKTDTVLG----------------DAHRHSD-HTGQTHGPPTPPTTPK---------------TDLHQASNGSKQELRLEGRRLVDSGRQNIDFSNVDISELSSEVISNMDTFDVHEFDQYLP-------LNGHSALATEPSQATASGSYGGASYSHSGATGIGASPVWAHKGAPSASASPTEAGPLRPHIKTEQLSPSHYNDQSHGSPGRADYGSYSAQASVTTAASATAASSFASAQCDYTDLQASNYYSPYPGYPPSLYQYPYFHSSRRPYASSLLNGLSMPPAHSPSSNWDQPVYTTLTRP--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q04886-1", "uniprot_id": "SOX8_MOUSE", "id": "Q04886-1", "name": "Transcription factor SOX-8", "aln": "MLDMSEARAQPPCSPSGTASSMSHVEDSDSDAPPSPAGSEGLGRAG---GGGRGDTAEAADERFPACIRDAVSQVLKGYDWSLVPMPVRGGGGGTLKAKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEEAERLRVQHKKDHPDYKYQPRRRKS-VKTGRSDSDSG---------------------------------------------TELGHHPGG-PMYKADAVLG----------------EAHHHSDHHTGQTHGPPTPPTTPK---------------TDLHQASNGSKQELRLEGRRLVDSGRQNIDFSNVDISELSSEVISNMDTFDVHEFDQYLP-------LNGHSALPTEPSQATASGSYGGASYSHSGATGIGASPVWAHKGAPSASASPTEAGPLRPQIKTEQLSPSHYNDQSHGSPGRADYGSYSAQASVTTAASATAASSFASAQCDYTDLQASNYYSPYPGYPPSLYQYPYFHSSRRPYASPLLNGLSMPPAHSPSSNWDQPVYTTLTRP--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P57073-1", "uniprot_id": "SOX8_HUMAN", "id": "P57073-1", "name": "Transcription factor SOX-8", "aln": "MLDMSEARSQPPCSPSGTASSMSHVEDSDSDAPPSPAGSEGLGRAGVAVGGARGDPAEAADERFPACIRDAVSQVLKGYDWSLVPMPVRGGGGGALKAKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEEAERLRVQHKKDHPDYKYQPRRRKS-AKAGHSDSDSG---------------------------------------------AELGPHPGGGAVYKAEAGLG----------------DGHHHGD-HTGQTHGPPTPPTTPK---------------TELQQA--GAKPELKLEGRRPVDSGRQNIDFSNVDISELSSEVMGTMDAFDVHEFDQYLP-------LGG--PAPPEPGQA-----YGGA-YFHAGAS-----PVWAHKSAPSASASPTETGPPRPHIKTEQPSPGHYGDQPRGSP---DYGSCSGQSSATPAAP---AGPFAGSQGDYGDLQASSYYGAYPGYAPGLYQYPCFHSPRRPYASPLLNGLALPPAHSPTSHWDQPVYTTLTRP--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N736-1", "uniprot_id": "A0A8M1N736_DANRE", "id": "A0A8M1N736-1", "name": "", "aln": "---MSEEREK--CSSPTGSCSSECPDECDSDPSCSPAGPAAL-RMG--------QQAEDEDGRFPVCIRDAVSQVLKGYDWSLVPMPVRVSGSG--KSKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLTESEKRPFVEEAERLRVQHKKDHPDYKYQPRRRKS-VKPGHAESEAG---------------------------------------------SELMQH-----MYKAEPGMGRL-------------TGSPDHITDHTGHTHGPPTPPTTPK---------------TEHPQAP------------------KQNIDFSNVDISELSTDVIGNL-TFDLQEFDQYLP-------LTP-----------------------DQGACS---------RRAPPAGAH---LHPQRVHIKTEQRSPQHYSEHS------------STLYSSS------------SAQCEYT---EHSFYSPYSSYP---YPYPYLHR-------PILN---IPAPHSSSAHWDPPVYTTLSRP--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0R4ITJ3-1", "uniprot_id": "A0A0R4ITJ3_DANRE", "id": "A0A0R4ITJ3-1", "name": "", "aln": "---MSKEPDK-----AASIPESCFLDDVDSDSPSSPSVSDDPGSRAAP------PPDTDGDARFPVCIRDAVSQVLKGYDWSLVPMPMQ--GSRSLKDKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEEAERLRLQHKKDYPDYKYQPRRRKS-LKPGQNEAEAG---------------------------------------------AEKNLHHTD-PIYKTEAGMR-----------------AMHHQTIHGVQPHGPPTPPTTPK---------------SDQHQS-----------MKRLSENARQNIDFSNVDISELSSDVIGSISQFDVREFDQYLP-------LNG--HTESGGGQHSSPGCFSTSFHHHSGASA---------WNKPSGSPSTSSANQQRPLIKTEQLSPSHYGQSHG-----------SPT---------------QSELSDCADMQNSAYFTTFSGYPAGIYQYPYFHSTRRSYMTPVLN-TLSSPSHSPGTNWEQPVYTTLTRP--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VA17-1", "uniprot_id": "Q9VA17_DROME", "id": "Q9VA17-1", "name": "", "aln": "---MSD--------SSSSNCSKDRAKPVETLVLANYALKAEQKKAQ-----------GQGGRKEDERITTAVMKVLEGYDWNLVQASAKAPTDR---KKEHIKRPMNAFMVWAQAARRVMSKQYPHLQNSELSKSLGKLWKNLKDSDKKPFMEFAEKLRMTHKQEHPDYKYQPRRKKARVLPSQQSGEGGSPGPEMTLSATMGSSGKPRSSNSNGQRRAGKGNAAADLGSCASTISHANVGSNSSDVFSNEAFMKSLNSACAASLMEQSLIETGLDSPCSTASSMSSLTPPATPYNVAPSNAKASAANNPSLLLRQLSEPVANAGDGYGVLLEAGREYVAIGEVNYQGQSAGVQSGAEGGGAGQEMDFLENINGYGGYTGSRVSYPAYSYPANGGHFATEEQQQQQALQASEALNYKPAAADIDPKEIDQYFMDQMLPMTQHHHPHHTHPLHHPLHHSPPLNSSASLSSACSSASSQQPVAEYYEHLGYSPAASSASQNPNFGPQQPYANGAASMTPTLGDPAPQQELQSQQQEQQHQNPSQHHLWGTYTYVNP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **. . . . :: . : . : * ** :**:****.** . : . * *:**************** ::.*****:*:****:*****: *.:*:*:**:* **:**: **:::*********:*: ..: ..:.* :. ::. :. : . . .. ***:** : : :: : :.:*: . *: * . . : ::* . * : *:: * * : . . . . : :. : :: * : ", "identical_positions": 83, "similar_positions": 88, "identity": "14.98%" }, { "cls_id": "homologset.agr.RGD:1309073", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CAT8-1", "uniprot_id": "FBX48_MOUSE", "id": "Q8CAT8-1", "name": "F-box only protein 48", "aln": "MKKTSKKNNNFKIPGTELNSADAERGKEESQRNFVELLPLEVTYKIFSQLDIQSLCRASRTCTGWNCAIRNNDSLWKPHCLTIRAVCQREIDDDIKSGYTWRVILLRNYQKSKVKYEWLSGRYSNIRSPVNLPEKAMCPMDADTWGEILDAELEREVEKLQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0M155-1", "uniprot_id": "A0ABK0M155_RAT", "id": "A0ABK0M155-1", "name": "F-box only protein", "aln": "MKKTSK-NSNAKVPGMELNSEDAEGGRKENQSNFVDLLPLEVTFNIFSQLDIPSLCSASRTCTSWNHAIRNNDSLWKPHCLSIRAVCQREVDDDIENGYTWRVILLRNYQKSKVKNEWLSGRYSNIRSPVSLPEKAMCPMDADTWGEILDAELGREVEKLQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5FWF7-1", "uniprot_id": "FBX48_HUMAN", "id": "Q5FWF7-1", "name": "F-box only protein 48", "aln": "MHKNSKRNNNLRVSHTEANSVDAEKEKNESQNNFFELLPAEITFKIFSQLDIRSLCRASLTCRSWNDTIRNSDSLWKPHCMTVRAVCRREIDDDLESGYSWRVILLRNYQKSKVKHEWLSGRYSNICSPISLPEKIMYPMDADTWGEILEAELER------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:*.** *.* ::. * ** *** ::*.* **.:*** *:*::******* *** ** ** .** :***.********:::****:**:***::.**:*************** ********** **:.**** * ***********:*** * ", "identical_positions": 106, "similar_positions": 29, "identity": "65.84%" }, { "cls_id": "homologset.agr.RGD:1309074", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P07360-1", "uniprot_id": "CO8G_HUMAN", "id": "P07360-1", "name": "Complement component C8 gamma chain", "aln": "MLPPGTATLLTLLLAAGSLGQKPQRPRRPASPISTIQPKANFDAQQFAGTWLLVAVGSACRFLQEQGHRAEATTLHVAPQGTAMAVSTFRKLDGICWQVRQLYGDTGVLGRFLLQARDAR---GAVHVVVAETDYQSFAVLYLERAG----QLSVKLYARSLPVSDSVLSGFEQRVQEAHLTEDQIFYFPKYGFCEAADQFHVLDEVRR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B3EY83-1", "uniprot_id": "LCN12_RAT", "id": "B3EY83-1", "name": "Epididymal-specific lipocalin-12", "aln": "-MGPWWALWLILTLPQILGGQSPTMPQG-------FSQMTSFQSNKFQGEWFVLGLADNTYKREHRPLLHSFITLFKLRDNSEFQVTNSMTRGKHCSTWSYTLIPTNKPGQFTRDNRGSGPGADKENIQVIETDYVKFALVLSLRQASNQNITRVSLLGRDWKITHKTIDRFICLTKTQNLTKNNLLFPDLTDWLLDPKVC--------", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * * * * *. **.* *: :. :.*::::* * *:::.:.. :.: . **. :.: : *:. . . * *. *:* : *.: . :: * **** .**:: * . *.* .*. ::...:. * .: :**:::::: .: .. ", "identical_positions": 35, "similar_positions": 67, "identity": "16.75%" }, { "cls_id": "homologset.agr.RGD:1309075", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K938-1", "uniprot_id": "A0A0G2K938_RAT", "id": "A0A0G2K938-1", "name": "Solute carrier family 9 member C1", "aln": "TGMEEVFENLTTTHNVKLSNAWLDLLKSVFLSTPQDLPEIILILSLICTIGAFLNMHLKDFPIPLPVILFLIGCCFEILSFASTQIQLYADAIQWMDPDMFFGIFTPVIIFNVAFDMDIYMLQKLFWQILLITIPGFMINYTLILWYLQSVNKLSLKTIPWLLFSAVLISSDPMLTSASIRDLGLSRSLTNLINGESLLTSVISLIIYSAVVQISFKSKH-MNHTLAHKVMSTAWSYLVESFITGILITKAIQLWMATIFGDDVNHITLIFSVLYLIFYVCELIGMSGIFTLATIGLFLNSTSFKPGVEA-FLLEFWNCLSFIGFLMVFTFIGLLIPAHTYLYISFSDVYYSLNIYFTLIVLRLLVFLLMSPILSRLGHGFSWRWAFIMVWSEMKGTPNINMALLLAYSDVSLGSERERSQILFHGVSVCVITLIVNRFILPMAVIKLGLRDVTSTKYKSVYYTFQHFQELTKSTAMALKFDKDLANADWNMVDKAIILQNPYALNQEETTEHQKVKCPDCNKEIDETLNIEAMELANRRLLSAQIASYQRQYRNEILSQSAMQVLVGAAGSFGEKKGEYMSPENIKNYSESKKLLSFLRKLLLNWVYNTKKDKGVPSRYMFLHACHSIVFTNEFEYTGYIAVLMNTYPMIICWISRLKDIYQYEIKCANYYFLTFYILEALLKVAAMRKEFFSHTWLLFELGITLVGILDIILIETDSISYKFDLTETVVFMNVVRLLRILRILKLITPKLLQVIDKRMSQQISFRYAILKGYVQGEMDVLNIIDQIASSKQAKQILLKRVIRNMDHAMKELGYLEYDHPEIAVTMKTKEEVNVMLNMAREIVKAFRSKGIIHKVEGAEINKLIMAKKKQVLELQSVIQPLNVEEAPYYIPWLSEDPEAISFIQEKAKVVTFDCGNNIFEEGDEPEGIYVIISGMVKLKRSKPHLEMDRVSSESEVAQTRSYTLPHTEYLLSGEIIGELNCLTKERMQYSATCKTVVETYFIPISHLYEGFEKKYPNMKYKMWQKIGLAITAQKIRENLSFEDWNYKMQLKLCNVFVRDIPKTTKTDIYDETVTHVVLIHGSAEDCQLRKIYKAPFLIPVTCHQIQGLEEFTKVMIIQTSVAVRKFRWNVKKYNPPRRISMKPDS-TESLETLNESSEDDEDKKENEENEEYLEDI------------------IDISSVSKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6UJY2-1", "uniprot_id": "SL9C1_MOUSE", "id": "Q6UJY2-1", "name": "Solute carrier family 9 member C1", "aln": "MEMEEISENLTASHSIKLTNMWLELLKSVFLSTPQDLPEIILILSLICTVGAFLNMHLKDFPIPLPVILFLIGCCFEILSFASTQIQIYADAIQWMDPDIFFGIFTPVIIFNVAFDMDIYMLQKLFWQILVITIPGFLINYTLILWYLQSVNKLSLKTVPWLLFSAVLISSDPMLTSASIRDLGLSRSLTNLINGESLLTSVLSLVIYSGVVHIRFKSKS-VNHTLAHKVMSTAWSYIVESFITGIVFTKVIQLWMATIFGDDVNHITLIFSVLYLIFYVCELVGMSGIFTLATIGLFLNSTSFKPGVEA-FLLEFWNCLSFIGFLMVFTFIGLLIPAHTYLHISFSDVYYSLNIYFTLIVLRLLVFLLMSPILSRLGHGFSWRWAFIMVWSEMKGTPNINMALLLAYSDISLGSERERSQILFHGVSVCVITLIVNRFILPMAVTKLGLRDVTSTKYKSVYYTFQHFQELTKSTAMALKFDKDLANADWNMVDNAIILQNPYAMNQEEITEHQKVKCPDCNKEIDETLNIEAMELTNRRLLSAQIASYQRQYRNEVLSQSAVQVLVGAAGSFGEKKGEYMSPENIKNFSESKKLLSFLRKLLLNWVYNTKKDKGVPSRYMFLHACHRIVFTNEFEYTGYLVVLMSTYPMIICWISRLKDIYDNEIKCANYYFLAFYILEALLKVAAMRKEFFSHTWLLFELGITLVGVLDIILIETDSISYNFDLTETVVFMNVIRLLRILRILKLVTPKLLQIIDKRMSQQISFRYSILKGYVQGEMDVLNIIDQIASSKQTKQILLKRVMRNMEHAMKELGYLEYDHPEIAVTMKTKEEINVMLNMAREIVKAFRSKGIIHKVEGTEINKLIMAKKIQVLDLQSVIQPFNVEEAPCNIPWLSEDPEAITFIQEKAKVVTFDCGNNIFEEGDEPEGIYVIISGMVKLKRSKPHLEMERVSAES---EIKIHPLPHTEYLLSGEIIGELNCLTKERMQYSATCKTVVETYFIPISHLYEGFEKRCPNMKHKMWQKIGLAITAQKIREHLSFEDWNYKLQLKLCNAFIRDIPKSMKTDIYDETVTHVVLIHGSAEDCQLRKIYKAPFLIPVTCHQIQGMEDFTKVMIIQTSIAVRKFRWNVRKYIPPRRISMKPDSERESFETLDETSEEDNGKKENQENEELIEEN------------------INI------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4G0N8-1", "uniprot_id": "SL9C1_HUMAN", "id": "Q4G0N8-1", "name": "Solute carrier family 9 member C1", "aln": "---------------------MAGIFKEFFFST-EDLPEVILTLSLISSIGAFLNRHLEDFPIPVPVILFLLGCSFEVLSFTSSQVQRYANAIQWMSPDLFFRIFTPVVFFTTAFDMDTYMLQKLFWQILLISIPGFLVNYILVLWHLASVNQLLLKPTQWLLFSAILVSSDPMLTAAAIRDLGLSRSLISLINGESLMTSVISLITFTSIMDFDQRLQSKRNHTLAEEIVGGICSYIIASFLFGILSSKLIQFWMSTVFGDDVNHISLIFSILYLIFYICELVGMSGIFTLAIVGLLLNSTSFKAAIEETLLLEFWTFLSRIAFLMVFTFFGLLIPAHTYLYIEFVDIYYSLNIYLTLIVLRFLTLLLISPVLSRVGHEFSWRWIFIMVCSEMKGMPNINMALLLAYSDLYFGSDKEKSQILFHGVLVCLITLVVNRFILPVAVTILGLRDATSTKYKSVCCTFQHFQELTKSAASALKFDKDLANADWNMIEKAITLENPYMLNEEETTEHQKVKCPHCNKEIDEIFNTEAMELANRRLLSAQIASYQRQYRNEILSQSAVQVLVGAAESFGEKKGKCMSLDTIKNYSESQKTVTFARKLLLNWVYNTRKEKEGPSKYFFFRICHTIVFTEEFEHVGYLVILMNIFPFIISWISQLNVIYHSELKHTNYCFLTLYILEALLKIAAMRKDFFSHAWNIFELAITLIGILHVILIEIDTIKYIFNETEVIVFIKVVQFFRILRIFKLIAPKLLQIIDKRMSHQKTFWYGILKGYVQGEADIMTIIDQITSSKQIKQMLLKQVIRNMEHAIKELGYLEYDHPEIAVTVKTKEEINVMLNMATEILKAFGLKGIISKTEGAGINKLIMAKKKEVLDSQSIIRPLTVEEVLYHIPWLDKNKDYINFIQEKAKVVTFDCGNDIFEEGDEPKGIYIIISGMVKLEKSKPGLGIDQMVESK----EKDFPIIDTDYMLSGEIIGEINCLTNEPMKYSATCKTVVETCFIPKTHLYDAFEQCSPLIKQKMWLKLGLAITARKIREHLSYEDWNYNMQLKLSNIYVVDIPMSTKTDIYDENLIYVILIHGAVEDCLLRKTYRAPFLIPITCHQIQSIEDFTKVVIIQTPINMKTFRRNIRKFVPKHKSYLTPGL-IGSVGTLEEGIQEERNVKEDGAHSAATARSPQPCSLLGTKFNCKESPRINLRKVRKE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::*..*:** :****:** ****.::***** **:*****:******:**.**:***:*:*:* **:*****.**:** *****::*..***** ***********:*:****::** *:**:* ***:* **. ******:*:*******:*:********** .*******:***:**: ::.::.: : : *****.:::. **:: **: **: :* **:**:*:********:****:******:***:********* :**:*******..:* :*****. ** *.*******:**********:*.* *:*******:******:*.:**:**:***:** ***** **** ***** *************: :**::*:******** **:***:*******:** *****.******** ***********:* ***************:::** *:*** :*:** *********.******* :* *****:*******************:*****:******* *******: ** :.***:***:* ::* ***********:*:* **:*:*:: ** ****:***:.**:.:**. :*:**.***:*: **. *:* :** **::********:*****:****:* :***.***:*:*.:**** *:*.* *: **.:**::*::::*****:**::*****:******:* :* *.********* *::.*****:**** **:***:*:***:**:****************:*****:******* **:*** **** *.**: ********* :**: **:*:*:.***. ****.:: : *.***************:********:***:********::*** * :::: .. : ..: .*:*:********:****:* *:*********** *** :***:.**: * :* *** *:******:****:**:*****::****.* :: *** : *******.: :*:****:.*** *** *:******:******.:*:****:****.: ::.** *::*: * :: :.*. *. **:* :::.. **: :. *:: ", "identical_positions": 763, "similar_positions": 263, "identity": "63.37%" }, { "cls_id": "homologset.agr.RGD:1309076", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L9N7-1", "uniprot_id": "A0ABK0L9N7_RAT", "id": "A0ABK0L9N7-1", "name": "", "aln": "------------------------------------------------------------------------------------------MSSAAKSQVLEETAPGCEE-EPKGKTLFTWGSLFGHRSEKIVFTKGDGSPEESLLTVTITETTVIESDLGVWSSRALIYLTLWFFFSFCTLFLNKYILSLLEGEPSMLG--AVQMLSTTLIGCVKIFVPCCLYQHKTRLSYPPNFIMTMLFVGLMRFATVVLGLVSLKNVAVSFAETVKSSAPIFTVIMSRMILGEYTGLLVNLSLIPVMGGLALCTATEISFNILGFSAALSTNIMDCLQNVFSKKLLSGDKYRFSAPELQFYTSAAAVALLIPAWTFFMDVPVIGGSGKSFSYSQDIVLLLLTDGALFHLQSVTAYALMGKISPVTFSVASTVKHALSIWLSIIVFGNKITSLSAIGTILVTVGVLLYNKARQYQQETMQSLVTATSQGPNDDTEPLVSQDSRQHH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C811-1", "uniprot_id": "S35E2_MOUSE", "id": "Q8C811-1", "name": "Solute carrier family 35 member E2A", "aln": "------------------------------------------------------------------------------------------MSAAAKSQVPEEAAPGCEE-EPKGKTLLTWGSLFGHRSEKIVFTKGDGSPEESLLTVTITETTVIESDLGVWSSRALIYLTLWFFFSFCTLFLNKYILSLLEGEPSMLG--AVQMLSTTLIGCVKIFVPCCLYQHKTRLSYPPNFIMTMLFVGLMRFATVVLGLVSLKNVAVSFAETVKSSAPIFTVIMSRMILGEYTGLLVNLSLIPVMGGLALCTATEISFNILGFSAALSTNIMDCLQNVFSKKLLSGDKYRFSAPELQFYTSAAAVALLIPAWTFFMDIPVIGRSGKSFSYSQDIVLLLLTDGALFHLQSVTAYALMGKISPVTFSVASTVKHALSIWLSIIVFGNKITSLSAIGTILVTLGVLLYNKARQYQQETMQSLVTATSRNPEDDTEPLVPQDSRQHH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0CK96-1", "uniprot_id": "S352B_HUMAN", "id": "P0CK96-1", "name": "Solute carrier family 35 member E2B", "aln": "------------------------------------------------------------------------------------------MSSSVKTPALEELVPGSEE-KPKGRSPLSWGSLFGHRSEKIVFAKSDGGTDENVLTVTITETTVIESDLGVWSSRALLYLTLWFFFSFCTLFLNKYILSLLGGEPSMLG--AVQMLSTTVIGCVKTLVPCCLYQHKARLSYPPNFLMTMLFVGLMRFATVVLGLVSLKNVAVSFAETVKSSAPIFTVIMSRMILGEYTGLLVNLSLIPVMGGLALCTATEISFNVLGFSAALSTNIMDCLQNVFSKKLLSGDKYRFSAPELQFYTSAAAVAMLVPARVFFTDVPVIGRSGKSFSYNQDVVLLLLTDGVLFHLQSVTAYALMGKISPVTFSVASTVKHALSIWLSVIVFGNKITSLSAVGTALVTVGVLLYNKARQHQQEALQSLAAATGRAPDDTVEPLLPQDPRQHP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0CK97-1", "uniprot_id": "S35E2_HUMAN", "id": "P0CK97-1", "name": "Solute carrier family 35 member E2A", "aln": "------------------------------------------------------------------------------------------MSSSVKTPALEELVPGSEE-KPKGRSPLSWGSLFGHRSEKIVFAKSDGGTDENVLTVTITETTVIESDLGVWSSRALLYLTLWFFFSFCTLFLNKYILSLLGGEPSMLG--AVQMLSTTVIGCVKTLVPCCLYQHKARLSYPPNFLMTMLFVGLMRFATVVLGLVSLKNVAVSFAETVKSSAPIFTVIMSRMILGEYTGRPS-------------------------------------------------DREEREELQLQPGRGAAASDRRSP-------VPPSERHG---------------------------VRPHGENLPGDFQVP------------------------------------------QALHRVALSMALPC---------PMLPAS-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P39542-1", "uniprot_id": "YJT3_YEAST", "id": "P39542-1", "name": "Uncharacterized transporter YJL193W", "aln": "--------------------------------------------------------------MFQQLSASIR-----HNAHIIFLCISWYFISSLASQVTKQVLTVCPLPLFLGEFQFIYTAVLAWFTCYIAYSFPG---FYRIFPNGTFPEYYIDDRETSRAARKESKLSSLIIPPSKPILQTVLPLGLFQFVGKYFGHTATSLVPVSTVASIKTLSPMFILLLQKILKISTLKITLTLIFSLCTLVLGVWIIVQEDNRSPASSNELREFS-KYGVICAMISMFIFVLQNIYGKTVFTYRSQTDESQSNSGFSRQESPLPLYEKLDEKLVAKKKPKSYDKLTLMIYISLVGFCLSFGWFITLEFPVLFRYFFQINSSSTVIKAFP---VSLFLLNGTFHFIQAMITFHLLGEVSTLTYSIANLMKRFAIIAVSWVFIGRRITWLQVFGLVLNTLGLFLYERCTSQSKIKAKIRPE----------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P22215-1", "uniprot_id": "SLY41_YEAST", "id": "P22215-1", "name": "Uncharacterized transporter SLY41", "aln": "MIQTQSTAIKRRNSVHKNLFDPSLYQIPEPPRGGFQHQKKEYSKETFSNQVFGYDITSLKKRFTQLFPSNIQGYLPEVDLRITIICSIWYVTSSISSNLSKAILRTFNHPIALTELQFLVSAVLCVGFASIVNLFRLPRLKHTKFSKALNSFPDGILPEYLDGNFRSSILHKFLVPS-KLVLMTTFPMGIFQFIGHITSHKAVSMIPVSLVHSVKALSPIITVGYYKFFEHR--YYNSMTYYTLLLLIFGVMTTCWSTHGSKRASD-NKSGSSLIGLLFAFISMIIFVAQNIFAKNILTIRRKVGILPSSS-----TDDVTSKEGQPSLDKTRFSPLQVDKITILFYCSCIGFSLTLLPFLTGEL----------MHGGSVINDLTLETVALVAIHGIAHFFQAMLAFQLIGLLSSINYSVANIMKRIVVISVA-LFWETKLNFFQVFGVILTIAGLYGYDKWGLSKKDGRQA-------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :: : : . : ::: *. :. . * :. . :: . :.:: . *..::..: : .:* : * :. * : * : : :: :. : :: : : : :. : * . :.:. : ", "identical_positions": 8, "similar_positions": 60, "identity": "1.61%" }, { "cls_id": "homologset.agr.RGD:1309077", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZQG0-1", "uniprot_id": "D3ZQG0_RAT", "id": "D3ZQG0-1", "name": "", "aln": "--MAAPAKGMWYSLGPL-LRVVQTRD-----LDARRWVRALRRSPVRVLFPSGQ---VEERKRAPDKQPRKAVPEASS-QGQQQKQPLETSPSQTPHTWEE---------------------AGLRYDKACPGDRRLS-VMTIVKSRPFREKQGKILLEGRRLIADALKAGAVPKMFFFSRLEYIKELPVDK-----LKGVSLIKVKFEDIKDWSDLVTPQGIMGIFAKPD----PVKMTYPETQLHHSLPLLLICDNLRDPGNLGTILRSAAGAGCSKVLLTKGCVDAWEPKVLRAGMGAHFQVPIVNNVEWETVPNHLPPDTRVYVADNCGLYAQVQMSNKTGDRD-WACDRRFLKFHKN--EVDLDTKAR---------KDWLPKLEVQSYDLDWTEAPAALVIGGETHGVSLESLQLAESTGGKR--LLIPVVPGVDSLNSAMAASILLFEGKRQLRIKMGDLSRDSCCH--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5ND52-1", "uniprot_id": "MRM3_MOUSE", "id": "Q5ND52-1", "name": "rRNA methyltransferase 3, mitochondrial", "aln": "--MAAPAKGMWCSLGSL-LRVVQTRD-----LNARRWVRALRRSPVRVLSPSGQ---VEERKRAPDQQPRKAVPKASS-QGQRQKQPLETSPSQTPHTWEE---------------------AGLRYDKAFPGDRRLSSVMTIVKSRPFREKQGKILLEGRRLIADALKAGAVPKAFFFSRLEYVKELPVDK-----LKDVSLIKVKFEDIKDWSDLVTPQGIMGIFAKPD----PVKMTYPETPLHHTLPLVLICDNLRDPGNLGTILRSAAGAGCSKVLLTKGCVDAWEPKVLRAGMGAHFQVPIVNNVEWETVPNHLPPDTRVYVADNCGHYAQVQMSDKTGDRD-WACDRRFLKFHKY--EEDLDTKTR---------KDWLPKLEVQSYDLDWTGAPAAVVIGGETHGVSLESLQLAESTGGKR--LLIPVVPGVDSLNSAMAASILLFEGKRQLRIKVEDLSRDRSYH--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HC36-1", "uniprot_id": "MRM3_HUMAN", "id": "Q9HC36-1", "name": "rRNA methyltransferase 3, mitochondrial", "aln": "--MAALVRPARFVVRPL-LQVVQAWD-----LDARRWVRALRRSPVKVVFPSGE---VVEQKRAPGKQPRKAPSEASA-QEQREKQPLEESASRAPSTWEE---------------------SGLRYDKAYPGDRRLSSVMTIVKSRPFREKQGKILLEGRRLISDALKAGAVPKMFFFSRLEYLKELPVDK-----LKGVSLIKVKFEDIKDWSDLVTPQGIMGIFAKPD----HVKMTYPKTQLQHSLPLLLICDNLRDPGNLGTILRSAAGAGCSKVLLTKGCVDAWEPKVLRAGMGAHFRMPIINNLEWETVPNYLPPDTRVYVADNCGLYAQAEMSNKASDHG-WVCDQRVMKFHKYEEEEDVETGAS---------QDWLPHVEVQSYDSDWTEAPAAVVIGGETYGVSLESLQLAESTGGKR--LLIPVVPGVDSLNSAMAASILLFEGKRQLRGRAEDLSRDRSYH--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q566V3-1", "uniprot_id": "MRM3A_DANRE", "id": "Q566V3-1", "name": "rRNA methyltransferase 3A, mitochondrial", "aln": "--MAALMYNVSRGLVMLGERSLFQRERYQILVNSRRFLRGLRRRPVAVLYPDGERETLIKSKRATDITSQGFTQKGKARKDVTERAAYKNCSGFVSERAEESSQINKL------------KLAGLRFEKAPAGDNRLARVSSVARSRAFRDKEGKVLLEGRRLICDALSAGASPQMIFFSLLERLQELPLDK-----LQQAKLIKVKYEDIKLWSDLVTPQGLIAIFSKPD----ASRLTFPKDARLQSVPLFLICDNVRDAGNLGTILRCAAAAGGDRVLLSKGCVDAWEPKVLRSAMGAHFRLPVFPNLDWDDISKHLPKNVIVHVADNYSTSTKQLVSGQTEN---VSSDD----YSESDSDDDDDEEED---------EDSLPHVKPQVYHECWAQRSAALVIGGETHGLSVEALRLAEETDGKR--LFVPMAPGVESLNSAMAAGILLFEGRRQLLMLSDKLRRRARTKML", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1L2E4-1", "uniprot_id": "MRM3B_DANRE", "id": "A1L2E4-1", "name": "rRNA methyltransferase 3B, mitochondrial", "aln": "--MATRIASMRFRCALFQSALTLGRNE----VNIKRYVR--RRRAVSGVVSVNEP--TEISEGVISQTSERSSQHNNDITRNTDKSSIENPVSPNNSQPVQFSHINRQKVINLTSRTRFGEVDGLLYEKLHPGDKSLAKLARIAGSKKLREHQ--VVLEGKHLVCSALDAGAEAQTLYFSSVDALRELPLDK-----LRQTNVVKVKMEDAQVWSELDTSQEIIAIFKRPE----ASRLTFSEEKYGRAVPLTLICDTVRDPGNLGSVLRSAAAAGCHSVLLTKGCVDIWELKVLRAAMGAHFRLPIIPNLTWTDISNHLPKTSTVHVADNHSTTMGKHNDNTTPQKHRRPSDYGWVKGHQYQSKAHDDDDANDLCSLEDYCDENSKSLETQLYYTDWVAGHTSLIIGGETHGLSREALQLAERTSGRR--LLIPMVDGVDSLNSAIAAGVLLFEGRKQLLS-LEKIRV-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VW14-1", "uniprot_id": "MRM3_DROME", "id": "Q9VW14-1", "name": "rRNA methyltransferase 3, mitochondrial", "aln": "MLCNIFKRSLQANIRNVNNLNVLRLSS----SSGPRGEIQDALDIEANLFGNSDLRHEPMNTREALRKNRFAGRKPKVPFASVASRNLSAPSNPAPRVAPTPAPVIKD------------NELNLEFVRLTLQDPLTSTLLTTVRSRKRRDKNRQIIVEGRRLIQEALQCGLKMEVLLFSQKDQLALVKEEVGVAQVETGTKIYKVPQHDLKTWSSLVTPPGLMAIFDRPSDKGLEKNLAEQQRLGSQPFPITVVCDNIREPNNLGSIIRTCAALPCSQVVVTHGCCDPWESKALRGGCGGQFRVPIRDDVTWDELALTIPP----EAADDCHVFIAETNQRKRENNQ-----------------------------------------TIDYADIKGLGAHNLLIIGGESHGVSEEAYRFLNLVGGKGKCIYIPLAAGIDSLNVASALTLLLFELRRKLIHQASEKE--------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . * : .: . . . . . .* : : * : : . *: *::: :::**::*: .**..* : : ** : : : : ..: ** .* : **.* *. ::.** :*. .:: : :..*: ::**.:*:..***:::* .*. *::::** * ** *.**.. *.:*::*: :: * :. :* .**: . : : ::****::*:* *: :: : ..*: : :*:. *::*** * * :**** :::* . ", "identical_positions": 68, "similar_positions": 113, "identity": "14.29%" }, { "cls_id": "homologset.agr.RGD:1309078", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P04911-1", "uniprot_id": "H2A1_YEAST", "id": "P04911-1", "name": "Histone H2A.1", "aln": "--------MSGGKGGKAGSAAKASQSRSAKAGLTFPVG-RVHRLLRRGNYAQRIGSGAPVYLTAVLEYLAAEILELAGNAARDNKKTR-IIPRHLQLAIRNDDELNKLLGNVTIAQGGVLPNIHQNLLPKKSAKAT----------------------KASQEL-----------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P04912-1", "uniprot_id": "H2A2_YEAST", "id": "P04912-1", "name": "Histone H2A.2", "aln": "--------MSGGKGGKAGSAAKASQSRSAKAGLTFPVG-RVHRLLRRGNYAQRIGSGAPVYLTAVLEYLAAEILELAGNAARDNKKTR-IIPRHLQLAIRNDDELNKLLGNVTIAQGGVLPNIHQNLLPKKSAKTA----------------------KASQEL-----------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "C0HKE7-1", "uniprot_id": "H2A1N_MOUSE", "id": "C0HKE7-1", "name": "Histone H2A type 1-N", "aln": "--------MSG-RGKQGGKARAKAKTRSSRAGLQFPVG-RVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTESHH----------------------KAKGK------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "C0HKE4-1", "uniprot_id": "H2A1E_MOUSE", "id": "C0HKE4-1", "name": "Histone H2A type 1-E", "aln": "--------MSG-RGKQGGKARAKAKTRSSRAGLQFPVG-RVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTESHH----------------------KAKGK------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "C0HKE9-1", "uniprot_id": "H2A1P_MOUSE", "id": "C0HKE9-1", "name": "Histone H2A type 1-P", "aln": "--------MSG-RGKQGGKARAKAKTRSSRAGLQFPVG-RVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTESHH----------------------KAKGK------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "C0HKE2-1", "uniprot_id": "H2A1C_MOUSE", "id": "C0HKE2-1", "name": "Histone H2A type 1-C", "aln": "--------MSG-RGKQGGKARAKAKTRSSRAGLQFPVG-RVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTESHH----------------------KAKGK------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "C0HKE8-1", "uniprot_id": "H2A1O_MOUSE", "id": "C0HKE8-1", "name": "Histone H2A type 1-O", "aln": "--------MSG-RGKQGGKARAKAKTRSSRAGLQFPVG-RVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTESHH----------------------KAKGK------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "C0HKE6-1", "uniprot_id": "H2A1I_MOUSE", "id": "C0HKE6-1", "name": "Histone H2A type 1-I", "aln": "--------MSG-RGKQGGKARAKAKTRSSRAGLQFPVG-RVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTESHH----------------------KAKGK------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "C0HKE3-1", "uniprot_id": "H2A1D_MOUSE", "id": "C0HKE3-1", "name": "Histone H2A type 1-D", "aln": "--------MSG-RGKQGGKARAKAKTRSSRAGLQFPVG-RVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTESHH----------------------KAKGK------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "C0HKE5-1", "uniprot_id": "H2A1G_MOUSE", "id": "C0HKE5-1", "name": "Histone H2A type 1-G", "aln": "--------MSG-RGKQGGKARAKAKTRSSRAGLQFPVG-RVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTESHH----------------------KAKGK------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P04908-1", "uniprot_id": "H2A1B_HUMAN", "id": "P04908-1", "name": "Histone H2A type 1-B/E", "aln": "--------MSG-RGKQGGKARAKAKTRSSRAGLQFPVG-RVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTESHH----------------------KAKGK------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "C0HKE1-1", "uniprot_id": "H2A1B_MOUSE", "id": "C0HKE1-1", "name": "Histone H2A type 1-B", "aln": "--------MSG-RGKQGGKARAKAKTRSSRAGLQFPVG-RVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTESHH----------------------KAKGK------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AA54CQH7-1", "uniprot_id": "A0AA54CQH7_DANRE", "id": "A0AA54CQH7-1", "name": "Histone H2A", "aln": "--------MSG-RGKTGGKARAKAKTRSSRAGLQFPVG-RVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAVRNDEELNKLLGGVTIAQGGVLPNIQAVLLPKKTEKAESYAIYVYKVLKQVHPDTGISS-KAMGIMN---------------------------------SFVNDIFERIAGEASRLA----HYNKRSTITSREIQTAVR-------LLLPGELAKHAVSEGTKAVTKYTSSK------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3AWT1-1", "uniprot_id": "A0A8M3AWT1_DANRE", "id": "A0A8M3AWT1-1", "name": "Histone H2A", "aln": "--------MSG-RGKTGGKARAKAKTRSSRAGLQFPVG-RVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAVRNDEELNKLLGGVTIAQGGVLPNIQAVLLPKKTEKAAKGKXTAAIXLETKMSGRGKTGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYAQRVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGGVTIAQGGVLPNIQAVLLPKKTEKAAKGK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AA52P314-1", "uniprot_id": "A0AA52P314_DANRE", "id": "A0AA52P314-1", "name": "Histone H2A", "aln": "--------MSG-RGKTGGKARAKAKTRSSRAGLQFPVG-RVHRLLRKGNYAQRVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAVRNDEELNKLLGGVTIAQGGVLPNIQAVLLPKKTEKAAKGK----YKLKINMSGRGKTGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYAQRVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGGVTIAQGGVLPNIQAVLLPKKTEKAAKK-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58IZ20-1", "uniprot_id": "A0AC58IZ20_DANRE", "id": "A0AC58IZ20-1", "name": "Histone H2A", "aln": "--------MSG-RGKTGGKARAKAKSRSSRAGLQFPVG-RVHRLLRKGNYAQRVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAVRNDEELNKLLGGVTIAQGGVLPNIQAVLLPKKTEKAAKGK------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E7F5W3-1", "uniprot_id": "E7F5W3_DANRE", "id": "E7F5W3-1", "name": "Histone H2A", "aln": "--------MSG-RGKTGGKARAKAKTRSSRAGLQFPVG-RVHRLLRKGNYAQRVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAVRNDEELNKLLGGVTIAQGGVLPNIQAVLLPKKTEKATKGK------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P84051-1", "uniprot_id": "H2A_DROME", "id": "P84051-1", "name": "Histone H2A", "aln": "--------MSG-RGK-GGKVKGKAKSRSNRAGLQFPVG-RIHRLLRKGNYAERVGAGAPVYLAAVMEYLAAEVLELAGNAARDNKKTR-IIPRHLQLAIRNDEELNKLLSGVTIAQGGVLPNIQAVLLPKKTEKKA---------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "M0R7B4-1", "uniprot_id": "M0R7B4_RAT", "id": "M0R7B4-1", "name": "", "aln": "MSETAPAAPAAPAPVEKTPVKKKAKKTSSAAGKRKASGPPVSELITKAVAASKERSG--VSLAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGILVQTKGTGASGSFKLNKKASSGEAKPKAKKVGAAKAKKPAG----------------------SAKKPK---------------------------KATGSATPRKTKKTPKKAKKPGATAGAKKVSKSPKKVKAAKPKKAAKSPAKAKAPKAKATKPKASKPKANKAKKAAPRKK------", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . ::. * ** . * : .*: :. :.: :* * *:*: : *:* :: * :* : : ::.: : : :. ..: . :.* . *: : .* . ", "identical_positions": 16, "similar_positions": 44, "identity": "5.78%" }, { "cls_id": "homologset.agr.RGD:1309080", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U3Z2-1", "uniprot_id": "Q5U3Z2_RAT", "id": "Q5U3Z2-1", "name": "", "aln": "MTLEELVASDN------------AVQKMQAVTAAVEQLLVAAQRQDRLTVGVYEAAKLMNVDPDSVVLCLLAIDEEEEDDIALQIHFTLIQSFCCDNDIDIVRVSGMQRLAQLLGEPAETLGTNEARDLHCLLVTNCHTDSWK---SQGLVEVASYCEESRGNNQWVPYISLEER", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P22339-1", "uniprot_id": "GA45B_MOUSE", "id": "P22339-1", "name": "Growth arrest and DNA damage-inducible protein GADD45 beta", "aln": "MTLEELVASDN------------AVQKMQAVTAAVEQLLVAAQRQDRLTVGVYEAAKLMNVDPDSVVLCLLAIDEEEEDDIALQIHFTLIQSFCCDNDIDIVRVSGMQRLAQLLGEPAETLGTTEARDLHCLLVTNCHTDSWK---SQGLVEVASYCEESRGNNQWVPYISLEER", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75293-1", "uniprot_id": "GA45B_HUMAN", "id": "O75293-1", "name": "Growth arrest and DNA damage-inducible protein GADD45 beta", "aln": "MTLEELVACDN------------AAQKMQTVTAAVEELLVAAQRQDRLTVGVYESAKLMNVDPDSVVLCLLAIDEEEEDDIALQIHFTLIQSFCCDNDINIVRVSGMQRLAQLLGEPAETQGTTEARDLHCLLVTNPHTDAWK---SHGLVEVASYCEESRGNNQWVPYISLQER", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1Z6W5-1", "uniprot_id": "A1Z6W5_DROME", "id": "A1Z6W5-1", "name": "", "aln": "MVVEENCSMHHLERELDLELEIDMAMECAPIGRTIKSALLRAQSEARVIVGLSAAINVLSKSPEGSLFCLMAQ--PKDGDSATHMHEVLLEAFCYENDIYVIKVDDATKLSRILGQDSVES---------CCLVQKVWADAPEEQLTKAENQLVDYCEAHWDAPQ-QPIVQLPAV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.:** : .: . : .: :::. *: ** : *: **: : :::. .*:. ::**:* ::.* * ::* .*:::** :*** :::*.. :*:::**: : * ** : :*: : ::. ::..*** . * * :.* ", "identical_positions": 36, "similar_positions": 63, "identity": "20.57%" }, { "cls_id": "homologset.agr.RGD:1309081", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "F1M897-1", "uniprot_id": "F1M897_RAT", "id": "F1M897-1", "name": "", "aln": "MPVSKRRRAMAVPRGNPLACLLWILLLCGGYGSCQAQRAGCKSVQYDLVFLLDTSSSVGKEDFEKVRQWVANLVDTFEVGPGHTRVGVVRYSDRPTTAFELGHFSSREEVKAAARRITYHGGNTNTGDALRYITSRSFSAQAGGRPGNRAFKQVAILLTDGRSQDLVLDAAAAAHAAGIRIFAVGVGAALKEELDEIASEPKSAHVFHVSDFNAIDKIRGKLRRRLCENVLCPSVRVEGDRFKHTNGGTKEITGFDLMDLFSVKEILGKRENGAQSSYVRMGSFPVVQRTEDVFPQGLPDEYAFVTTFRFRKTSRKEDWYIWQVIDQYGIPQVSIRLDGENKAVEYNAVGAMEDAVRVVFRGPQVDNLFDRDWHKMALSIQAQNVSLYIDCMLVQTLPIEERENIDIQGKTVIGKRLYDSVPIDFDLQRIVIYCDSRHAELETCCDIPLGPCQVTVVTEPPPAPP--QLPTPGSEQIGFLKTINCSCPAGEKGERGFAGPVGLPGQKGDAGPIGLMGAPGPKGEKGDTGRGPFIQGGKGEKGSLGPPGPPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPAGQVGAPGLRGERGEMGPPGEKGERGLDGFPGKPGEIGEQGRPGPPGVAGLQGEKGDVGPAGPPGVPGSVVQREGLKGEQGAPGPRGHQGLPGPPGAPGLIGPEGRDGPPGPQGLRGKKGEVGPPGTPGSVGPQGPPGPPGVQGPPGPGGPPGLPGELGFPGKPGPAGHVGPPGKDGVNGPPGLPGSKGEPGDPGESGVPGMPGPRGEVGEQGLAGHPGEKGEVGLPGAPGFPGVRGEKGNQGEKGELGLPGLKGAQGEKGEVGPAGPPGLPGSPSIFTPHPRMPGEQGPKGEKGDPGEPGALGPQGHPGELGPRGPTGPPGAKGQDGAQGPPGTAGNPGAPGPAGLPGLSGPPGSVGSPGVRGTPGKDGERGEKGTAGEAGSPGPAGPRGDPGAPGLPGPPGKGKDGEPGLRGPPGLPGPLG--------------------TKGDRGTPGIPGSPGSRGDPGIGVAGPPGPSGQPGDKGPPGSRGLPGFPGPQGPAGQDGTPGNPGERGPPGKPGPSSLLSPEDINLLVKDVCNDCPPGPPGLPGLPGFKGDKGLPGKPGREGTEGKKGDTGPQGLPGPPGVAGPQGSKGEHGAEGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGNAGAAGLPGPQGPPGKEGPPGPQGPSGIPGIPGEEGKQGRDGKPGPPGEPGKTGEPGLPGAEGVRGPPGFKGHTGDPGPPGLRGEPGPTGPPGREGSPGKDGDTGPAGPQGPRGTRGPPGSSGSPGSPGDPGRPGAPGQKGNKGESGSPGLPGFLGPRGPPGEAGEIGAPGKEGAPGKPGEPGSKGEPGDPGIKGDKGPPGGKGQPGDPGTPGHKGHTGLMGPQGQPGESGPPGPPGPPGQPGFPGLRGESPSIDTLRRLIQEELGKQLEAKLAYLLAQMPPAHIKSSQGRPGPPGPPGKDGLPGRTGPMGEPGRPGQGGLEGPSGPMGPKGERGAKGDPGTPGVGLRGEMGPPGIPGQPGEPGYAKDGLPGSPGPQGETGPAGHPGPPGPPGPPGQCDPSQCAYFASLAARPSNVKGP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q7P1-1", "uniprot_id": "E9Q7P1_MOUSE", "id": "E9Q7P1-1", "name": "", "aln": "MPVFTSRRAMAVPRGNPLACLLWILLLWGGDGGCQAQRAGCKSVQYDLVFLLDTSSSVGKEDFEKVRQWVANLVDTFEVGPGHTRVGVVRYSDRPTTAFELGHFNSREEVKAAARRITYHGGNTNTGDALRYITSRSFSAQAGGRPGNRAFKQVAILLTDGRSQDLVLDAAAAAHAAGIRIFAVGVGAALKEELDEIASEPKSAHVFHVSDFNAIDKIRGKLRRRLCENVLCPSVRVEGDRFKHTNGGTKEITGFDLMDLFSVKEILGKRENGAQSSYVRMGSFPVVQRTEDVFPQGLPDEYAFVTTFRFRKTSRKEDWYIWQVIDQYGIPQVSIRLDGENKAVEYNAVGAMKDAVRVVFRGPRVDDLFDRDWHKMALSIQAQNVSLYIDCLLVQTLPIEERENIDIQGKTVIGKRLYDSVPIDFDLQRIVIYCDSRHAELETCCDIPLGPCQVTVVTEPPPAPP--QLPTPGSEQIGFLKTINCSCPPGEKGERGFAGPLGLPGQKGDAGPIGLMGAPGPKGEKGDSGRGPFIHGEKGEKGSLGPPGPPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPAGPVGAPGLRGERGERGPPGEKGERGLDGFPGKPGETGEQGRPGPPGVAGLQGEKGDVGPAGPPGVPGSVVQREGLKGEQGAPGPRGHQGLPGPPGAPGLIGPEGRDGPPGPPGLRGKKGEMGPPGTPGALGPQGPPGPPGVPGPPGPGGPPGLPGELGFPGKPGPAGHAGTPGKDGLNGPPGLPGSKGEPGDSGESGVPGMPGPRGEVGERGLAGHPGEKGEVGLPGAPGFPGVHGEKGDQGEKGELGLPGLKGARGEKGEVGPAGPPGLPGSPSVFTPHPRMPGEQGPKGEKGDPGEPGALGPQGHPGELGPRGPIGPPGAKGHDGAQGPPGAAGNPGAPGPAGPPGLSGPPGSLGSPGVRGAPGKDGERGEKGTAGEEGSPGPAGPRGDPGAPGLPGPPGKGKDGEPGLRGPPGLPGPLG--------------------IKGDRGTPGIPGSPGSRGDPGIGVAGPPGPSGRPGDKGPPGSRGLPGFPGPQGPAGQDGAPGNPGERGPPGKPGPSSLLSPEDINLLVKDVCNDCPPGPPGLPGLPGFKGDKGLPGKQGREGTEGKKGDTGPPGPPGPPGVAGPQGSQGERGAEGEVGQKGEQGHPGVPGFMGPPGNPGPPGADGNAGVAGPPGPQGPQGKEGPPGPQGPSGIPGVPGEEGKQGRDGKPGPPGEPGKTGEPGLSGAEGARGPPGFKGHTGDPGPPGLRGEPGIAGPSGRDGSPGKDGDTGPAGPQGPRGTRGPPGSSGSPGSPGDPGRPGALGQKGNKGESGSPGLPGFQGPRGPPGEAGEVGAPGKEGAPGKPGEPGSKGERGDPGIKGDKGPPGGKGQPGDPGTPGHKGHTGLMGPQGQPGESGPPGPPGPPGQPGFPGLRGESPSMDTLRRLIQEELGKQLEAKLAYLLAQMPPAHMKSSQGRPGPPGPPGKDGLPGRTGPMGEPGRPGQGGLEGPSGPMGPKGERGAKGDPGTPGVGLRGEMGPPGIPGQPGEPGYAKDGLPGSPGPQGETGLAGHPGPPGPPGPPGLCDPSQCAYFASLAARPSNVKGP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NFW1-1", "uniprot_id": "COMA1_HUMAN", "id": "Q8NFW1-1", "name": "Collagen alpha-1(XXII) chain", "aln": "---------MAGLRGNAVAGLLWMLLLWSGGGGCQAQRAGCKSVHYDLVFLLDTSSSVGKEDFEKVRQWVANLVDTFEVGPDRTRVGVVRYSDRPTTAFELGLFGSQEEVKAAARRLAYHGGNTNTGDALRYITARSFSPHAGGRPRDRAYKQVAILLTDGRSQDLVLDAAAAAHRAGIRIFAVGVGEALKEELEEIASEPKSAHVFHVSDFNAIDKIRGKLRRRLCENVLCPSVRVEGDRFKHTNGGTKEITGFDLMDLFSVKEILGKRENGAQSSYVRMGSFPVVQSTEDVFPQGLPDEYAFVTTFRFRKTSRKEDWYIWQVIDQYSIPQVSIRLDGENKAVEYNAVGAMKDAVRVVFRGSRVNDLFDRDWHKMALSIQAQNVSLHIDCALVQTLPIEERENIDIQGKTVIGKRLYDSVPIDFDLQRIVIYCDSRHAELETCCDIPSGPCQVTVVTEPPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDPSQCAYFASLAARPGNVKGP", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** ***.:* ***:*** .* *.***********:************************************.:******************* *.*:*********::****************:****.:***** :**:************************ *********** ******:********************************************************************************************* ***************************************.***********************:*********.:*::********************:*** ******************************************************** *************.** : *******************.***** *.***:**** *** *.** :*********** * *** :* ******** ******************************************.* ******:***** *. ****************: *:******.**** *********************:***************** ****** * *********** *******::**** ** :* ********* *******.******:********.* .*.***** ***** **:*****: **.*:** ** ***:**:****:******.***********:****:************** :*****.**********:.*:********************* ** * **:******:** *******::**:*.**:******** .* ** ******:*:**:**:***********:*** *****.***************************.******** *****:************************* *****.*****************:**:************** ****** *****.*************************:*** **********::** * *****:******:**:**:*******:*********************** **.** ** **. *************:**:******:**************:*****.*.**.************.*.** ***.* * .*::* *********:*****:*.*****..*******:** .*: ****.***.******** ********.** *.*****.******** *** ********************** ************** ***.** ********************::***************::***********::*********************:********************:*************:****************************** ******** ***** ******** ****************.*****", "identical_positions": 1393, "similar_positions": 130, "identity": "85.2%" }, { "cls_id": "homologset.agr.RGD:1309083", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZHC3-1", "uniprot_id": "D3ZHC3_RAT", "id": "D3ZHC3-1", "name": "", "aln": "------MTGEVDSEVNLEVGDLKILSQEE----VDSGQGSFEALELFSERDSDEEIFVSKKPKSRKVLQD--SDSEAEDN--APEKPTYD-SAEENNENLHSGKSQTIKSISTALADSDESSMEGTPCQESLETQETPSLELSHQTASSADFTTDRKLSKALRR--EGTEGKAK--SKRRLEKEERTREKIRRLKK--KETRCEESDADRPLNDSGCLLE-----------DSDLFETGLEEEDDSPLEDEESLESIRAAVKNKMKNHKKKEPSLESETFSLEDESELSKGSGRKERKAAKLSKEALKKLHSETQRLVRESALNLPYHMPESKTIH--DFFKRKPRPSCQGSAMALLKSCKYQSGHHKEAINPADAAGMSADDPSKGSEQRTRAESAKETTILPEVSEEAGITAGSDEACGKDPVRGAELEIEETEKYSDGRP-SPGDRSVSQQESSISRSKDSENCHTGELTQSDPPALEGEELK---TTEEAEAGEGAAEQKTES-----------AVAPPGKARRFTVDRLRQLGVDVSSQPRLG--------------------ADEDSFVILDEPETNRELEALKQRFWRHANPAASPRAHQTLNVN-IIVKDLGTDGKEELKAEVVPVTLAAEKLEGASHTKPGEKLQMLKAKLQEAMKLRRLEERQKRQALFKLDNEDGFEEEEEEEE-----------MTDESEEDG---------EEEEEEEEEEEEEEEVGDMQETSEYLLGSEDTETKAEK--ETDKENTDASSDVGKPV-ALSVPKPLSSDSTLLLFKDT----SSKMGYFPTEEKSETD-----------EHMGKQSDKLDEDDSSSLLTKESSHNSSFELIGSTIPSYQPCNRHTGRGTSFLPTAG-FRSPSPGLFRGSLISSASKSSGKLSEPSLPIEDSQD---------LYTASPEPKTLFLGAGDFQFCLEDDTQS----QLLDADGFLNVRNHRNRYQALKPQLPLASMDENAMDANMDELLDLCTGQFTSQSEEKCQPRKND--------------QKENMEELLNLCSGKFPSQDASPVAPLELRTEERE-----------SGTEDPMEEALALCSG---SFPTDREEEGEEEEFGDFQLVSKENEFASDEGGHSDS-SDEELALDLEDDEEELLKQSEKMKRQMRLKKYLEDEAEVSGSDVGSEDEYDGEDIDEYEEDAIDEVLPSDEELESQIKKIHMKTMLDDDKRRLRLYQERYLADGDLHSDGPGRTRKFRWKHIDDTSQMDLFHRDSDDDQVEEQLDETEAKWRKERIEREQWLREQAQQGKIAAEEED-VGEDSQFMMLAKKVTAKALQKNASRAVAVQESKSVLSNPFETIRAGGAHQLKTGSLLNQPKAVLQKLATLSDLNPSAPRNSRNFVFHTLSPTK--AETAKSSSKPQVRRRGPSSMMSPSPKR----LKTNDSSPGPKRSIFRYLES", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80YR7-1", "uniprot_id": "CLSPN_MOUSE", "id": "Q80YR7-1", "name": "Claspin", "aln": "------MTGEVGSEVNLEVNDLKLLSQEAADSPVDSGQGSFETLEPLSERDSDEEIFVSKKPKSRKVLQD--SDSEAEDRDDAPEKPTYDDSAEDTQENLHSGKSQS-RSFPKALADSDESDMEETPSQESPETQEAPSLEPGHQTGHSVDFTTGRKLSKTLLR--EGAEGKAK--SKRRLEKEERTMEKIRRLKK--KETRCEESDADRPLNDSGCLLE-----------DSDLFETGLEEENDSALEDEESLESIRAAVKNKVKNRKKKEPTLESEAFSLEDGNELSKGSARKERKAARLSKEALKKLHSETQRLVRESALNLPYHMPESKTIH--DFFKRKPRPTCQGSAMALLKSCKYQSGHYKETVNPADAAGMGAEDSSRGSEQRTGAGIAAETNVLSEVSEEAGITAGSDEACGKDPVRRGELEIEETEKHSDDRPYSPGDRSMSQQESSIPRIEDNEGHQAGDLTESDPPALEGEELK---TVEKTDAKEGMPEQKTQSAAAAAVAVVTAAAAPPEKVRRFTVDRLRQLGVDVSSQPRLG--------------------ADEDSFVILDEPKTNRELEALKQRFWRHANPAASPRACQTVNVN-IIVKDLGTNGKEELKAEVVPVTLAAEKLEGASHAKPGEKLQMLKAKLQEAMKLRRLEERQKRQALFKLDNEDGFEEEEEEEE-----------MTDESEEDG---------EEE------------------TTEYLLGSEDTETKDEK--ETDKENTDTSSDIGKSV-ALCVPKPLSSDSTLLLFKDS----SSKMGYFPTEEKSETD-----------EYLAKQSDKLDEDDSSSLLTKESSHNSSFELIGSTIPSYQPCNRQIGRGASFLPTAG-FRSPSPGLFRGSLISSASKSSGKLSEPSLPVEDSQD---------LYTASPEPKTLFLGAGDFQFCLEDDTQS----QLLDADGFLNIRNHRHRYQAVKPQLPLASMDENAMDANMDELLDLCTGQFTSQPEEKCQPRKND--------------KKENMEELLNLCSGKFPTQDASPVAPLGLRSQEKE-----------SSTEDPMEEALALCSG---SFPTDREEEGEEEEFGDFQLVSKENGFASDEDEHSDS-NDEELALDLEDDEEELLKQSEKMKRQMRLKKYLEDEAEVSGSDVGSEDEYDGEEIDEYEEDVIDEVLPSDEELESQIKKIHMKTMLDDDKRRLRLYQERYLADGDLHSDGPGRTRKFRWKHIDDTSQMDLFHRDSDDDQVEEQLDETEAKWRKERIEREQWLREQAQQGKIAADEED-IGDDSQFMMLAKKVTAKALQKNASHTVVVQESKSVLRNPFETIRPGGAHQLKTGSLLNQPKAVLQKLAALSDLNPSAPRNSRNFVFHTLSPTK--AEAAKDSSKPQVRRRGLSSMMSPSPKR----LKTNGSSPGPKRSIFRYLES", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HAW4-1", "uniprot_id": "CLSPN_HUMAN", "id": "Q9HAW4-1", "name": "Claspin", "aln": "------MTGEVGSEVHLEINDPNVISQEEADSPSDSGQGSYETIGPLSEGDSDEEIFVSKKLKNRKVLQD--SDSETEDTNASPEKTTYDSAEEENKENLYAGKNTKIKRIYKTVADSDESYMEKSLYQENLEAQVKPCLELSLQSGNSTDFTTDRKSSKKHIHDKEGTAGKAKVKSKRRLEKEERKMEKIRQLKK--KETKNQEDDVEQPFNDSGCLLV-----------DKDLFETGLEDENNSPLEDEESLESIRAAVKNKVKKHKKKEPSLESGVHSFEEGSELSKGTTRKERKAARLSKEALKQLHSETQRLIRESALNLPYHMPENKTIH--DFFKRKPRPTCHGNAMALLKSSKYQSSHHKEIIDTANTTEMNSDHHSKGSEQTTGAENEVETNALPVVSKETQIITGSDESCRKDLVKNEELEIQEKQKQSDIRP-SPGDSSVLQQESNFLGNNHSEECQVGGLVAFEPHALEGEGPQ---NPEETDEKVEEPEQQNKSS----------AVGPPEKVRRFTLDRLKQLGVDVSIKPRLG--------------------ADEDSFVIL-EPETNRELEALKQRFWKHANPAAKPRAGQTVNVN-VIVKDMGTDGKEELKADVVPVTLAPKKLDGASHTKPGEKLQVLKAKLQEAMKLRRFEERQKRQALFKLDNEDGFEEEEEEEEE----------MTDESEEDGEEKVEKEEKEEELEEEEEKEEEEEEEGNQETAEFLLSSEEIETKDEK--EMDKENNDGSSEIGKAVGFLSVPKSLSSDSTLLLFKDS----SSKMGYFPTEEKSETD-----------ENSGKQPSKLDEDDSCSLLTKESSHNSSFELIGSTIPSYQPCNRQTGRGTSFFPTAGGFRSPSPGLFRASLVSSASKSSGKLSEPSLPIEDSQD---------LYNASPEPKTLFLGAGDFQFCLEDDTQS----QLLDADGFLNVRNHRNQYQALKPRLPLASMDENAMDANMDELLDLCTGKFTSQA-EKHLPRKSD--------------KKENMEELLNLCSGKFTSQDASTPASSELNKQEKE-----------SSMGDPMEEALALCSG---SFPTDKEEEDEEEEFGDFRLVSNDNEFDSDEDEHSDSGNDLALEDHEDDDEEELLKRSEKLKRQMRLRKYLEDEAEVSGSDVGSEDEYDGEEIDEYEEDVIDEVLPSDEELQSQIKKIHMKTMLDDDKRQLRLYQERYLADGDLHSDGPGRMRKFRWKNIDDASQMDLFHRDSDDDQTEEQLDESEARWRKERIEREQWLRDMAQQGKITAEEEEEIGEDSQFMILAKKVTAKALQKNASRPMVIQESKSLLRNPFEAIRPGSAQQVKTGSLLNQPKAVLQKLAALSDHNPSAPRNSRNFVFHTLSPVK--AEAAKESSKSQVKKRGPSFMTSPSPKH----LKTDDSTSGLTRSIFKYLES", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8IRB5-1", "uniprot_id": "CLSPN_DROME", "id": "Q8IRB5-1", "name": "Claspin", "aln": "MSESLAETAAAAENEEQADDSMEKLVFDEEDEQMVSGEDLLGGKSLIMSDDSEAEDGSQEKPLSPKDRRRRMMDSDQEEDAMDQGNGDSIKNSEDVEEEMVSRPKKKVSAIIDSDNDDEQQAEKKTQKEEGKQPVKSKKKRSQVNQEDQEKPVKSNKTKKAVKNKTQANKAEDDQDNPSKEDKPKKVVKNKKQTNKDGKPQTNEEYDHHQQHEKPAKTQKSKKLAKKQKQQEDDKEDNGTEQEKKKPSPKSKAKKSDKSKIDSLMDNEEDAGEDLKMYQEDQEPQKQKTKKSAKKTNKDSKEESGEDQEHQEQKKPLKKIKLDNIDTKEDKEQIVKPKKMAKKNKQKVLSDDESEENQNEKVDQDHDLKKMSSENELEMGSDKEDQEMQEPPKKAKKNKQRMDSESEDEIPKTESEKITSSPKNKLKGLVDSESEPEETAEEVSPVKNKLKGLVDSESEPELDNPEESAGEQEAPMESALSREKPKKAKVVRESAKKALEGMQAIQSEQQRLHREAHINVPYHQPKPRTLKEFLSRRTINAPLATALAGGSPMPSRQPRKSVGLRMTREELEAYAKLMEDRAKEATEFFKSESESDEEDDSENEEPMELKDNPGVMDEMLDNPKTPEQPKNDTEDMTSQAVIEVPVLGEDKTDDTVGDEAMVADSITEEEPIASTSTAAALKLADNFEIQQETNAKSPSKVCLVTEVVELPKLDLSTINITPSSKPATPKISEVIRQLKIEKSLDESPSLKGDPNMVIDLETGDMFAKKPTGVDDLLNRLMKTREAKKHKTTETVNILTTEHGKLEMSKVSIHLHEEEIAKEPKPGAGYMKMQEHLKTLITKKRMEDLRKKQAEEQEKMAEDEEEGMDVDEEYEPEDKPGYAEVTINEDEEIIDKVDSTAEDDGDAEENKNDADEDPEDNPVEDSEDEKNDSESEQECEANPEPETQTRKKNRIIKAFEDDNSDEDDLDLLQTPKPSNVAPITATQLQLSAHKLFDVETRRTASDEENELLDLCSGQFPQTQMLSSDAPSVDTAVISQIPMTQFGGSSQAADELEGLCSGTFATQLPSQAPTQQPEQQEESEVPAAVANRIVSSDEEAQEDALEVDKPRNKKLTKKRPKKKAKLGFSDDEDSDDEVEEFDEESDAEPVEEIPETFVDYDSEENEIVVEMTKKDRKIRAANFVDKEAELSESEWGSADEDE-KNMDEYDIELGDEDQFDRDKLRHELGQIHARKMMDQDIREVRKIKELLFEE---EEEGANRQRQFRWKNVEAGFSLDDNRTDNGEGNDGSGDEENEHLWRKIRYEREQLLLEKGLKPEVASPLSTSVINTS---NNGNSPAIRRLNIISSKKTTVEVKKNSPFLISKTIAGKQQKSAVRGSFLIRDQQTLSKLAGLTKGTSGDVDAAEGTISVKSAKAKNFVFATLTEEEHENRKRKAADILNSSTETGVNFIKKPKLEPRRDKCLIDQLL-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. . .: . .. : : : **:. : . **: * .:* . * : **: *: : *: :*:: : . . : : *.::. : : :*. :. . : . . ....* .* . :. .: . . : :* :: :: :: :* * :* * .: :... :.* :.* *:*.... ..:: :* :: :.. :.:.:. *: . * .: :* : :* .* :: .. :: :.:.: * : . *: : :.: :: .: *:: : .. :. * :..* : :.. : *.::. .: :: . : . ..* ... :. . :: :. : : . . : :*. .. .* **. * : .:: * :* . * : * : ::.. . *. : :::. * * .::. * :*.. . : :. . :: * ::.:: : * :.. . ::.: : .. .:. : : : * .: . * . .: *. *.** ::* : :.: .: * : : * .. : . *. *: .. .. :.: : . * ::::. :* .: **:. . **: .: * . * :* . ::*..: :. * * : . : : * . : : . . . . :. .*.... . . *:***:* *.***:* . : .:***... :**:: *: :..: : ..: . : :******:*:*.. . . . * ..: :** .****.*.:* .* .. . :*.. *. :. *:** : . .:...: :: : *.* . ..: .:*. . . . :.:*:*:: . * .*::* ::::.***:* *: ** ** : :::***: : ** . ::*. :: :** :.*:*:* *.:* :* : : ..:*..* *:****::: .:* : *..:.: . :*.* *** * **** * : . : :::: . : : * .:. : : *: :*: .:: .*. ::* :. **:* : : .*.*** *:. ... :.. : . : .* . :: ..: : ::* : : ..*.: :*. . :.:: * ", "identical_positions": 188, "similar_positions": 509, "identity": "12.76%" }, { "cls_id": "homologset.agr.RGD:1309085", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZN43-1", "uniprot_id": "NDUF6_RAT", "id": "D3ZN43-1", "name": "NADH dehydrogenase (ubiquinone) complex I, assembly factor 6", "aln": "MATSMLGSVPGPRPFGLAGLFRRRPPRDPWERV--RRLPRLSAVRRSVAAASGPGIPDSHLYCLELLRKRDYESYLCSLLFPAECQRSASALRAFNVELAQ-VKDSVSEKTIGLMRMQFWRKAVEDMFCDNPP-----HQPVAMELWKAVKRHNLTKRWLLRIIDEREKNLDDKAYRSIRELETYAENTQSSLLYLTLEVLGVKDVHADHAASHIGKAQGIVTCLRATPYHSSRRQVFLPMDVCVQHGVSQEDFLR-RNQDKNVRDVVYDIASQAHLHLKHARSFHSRVPAEAFPAFLQTVSLEDYLKKIQRVDFDIFHPSLQQKNTLLPLSLYIQSWRKRY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2AIL4-1", "uniprot_id": "NDUF6_MOUSE", "id": "A2AIL4-1", "name": "NADH dehydrogenase (ubiquinone) complex I, assembly factor 6", "aln": "MATSMLGSVRGPRPFGLANLFHRQPPRDAWERV--RRLPGPSAVRRSVAAASGPGIPGSHLYCLELLRKRDYESYLCSLLFPAECQRSASALRAFNVELAQ-VKDSVSEKTIGLMRMQFWKKAVEDMYCDNPP-----HQPVAIELWKAVKKHNLTKRWLMRIIDEREKNLDDKAYRSMQELENYAENTQGSLLYLTLEVLGVKDLHADHAASHIGKAQGIVTCLRATPYHSSRRQVFLPMDVCVQHGVSQEDFLR-RNQDKNVRDVVYDIASQAHLHLKHARSFHRSVPAEAFPAFLQTVSLEDYLKKIQRVDFDIFHPSLQQKNMLLPLSLYIQSWRKRY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q330K2-1", "uniprot_id": "NDUF6_HUMAN", "id": "Q330K2-1", "name": "NADH dehydrogenase (ubiquinone) complex I, assembly factor 6", "aln": "MAASAHGSVWGPLRLGIPGLCCRRPPLGLYARM--RRLPGPEVSGRSVAAASGPGAWGTDHYCLELLRKRDYEGYLCSLLLPAESRSSVFALRAFNVELAQ-VKDSVSEKTIGLMRMQFWKKTVEDIYCDNPP-----HQPVAIELWKAVKRHNLTKRWLMKIVDEREKNLDDKAYRNIKELENYAENTQSSLLYLTLEILGIKDLHADHAASHIGKAQGIVTCLRATPYHGSRRKVFLPMDICMLHGVSQEDFLR-RNQDKNVRDVIYDIASQAHLHLKHARSFHKTVPVKAFPAFLQTVSLEDFLKKIQRVDFDIFHPSLQQKNTLLPLYLYIQSWRKTY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9P823-1", "uniprot_id": "A0A8M9P823_DANRE", "id": "A0A8M9P823-1", "name": "NADH dehydrogenase (ubiquinone) complex I, assembly factor 6", "aln": "MSCAMASSISIKN-----GLFTTKKSLHVNIPN--PRCLQRQTEIKCTRAVTNSTRQHNEQYCIDIVRKKDYEGFLCSLLLPEAARRSALALRAFNVELAQ-IKDSVSHKTIGLMRMQFWKSAVEDIYRDDPP-----AQPVSAELWRAVRKHTLTRRWMLRIVSEREKDMEDRAYRNLQDLEAYGENTQSSLLYLLLETLGVKNVHADHAASHIGKAQGILTCLRATPFNSSRRKVYLPMDICMLHGASQEDFIR-GSRDQNIRDVVYDIASQAHVHLQHARSFAESVPHSAMPAFLQTVVLEDYLQRVRKVDFDVFHPSLQKRNPTLPLQLYLRSWRKIY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VYS5-1", "uniprot_id": "NDUF6_DROME", "id": "Q9VYS5-1", "name": "NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 homolog", "aln": "----MRRLVRNWN---CRLLFNAKSGQEIVSHAGIHQEAKTNAIPREKKVIEADKNGYGAKHCMSLVEKYDYENYLCTLLLPRELRRAAFALRAFNVEVSRSVSGHQIEPQIAKMRLKFWHDSIDKCFEPDSQRSYVEDQPVLRELKHTVGSRKLNKVYLRRLVTARER-PPTHAFESIRELEEYTEQTFSSLLLLLLEVGGVRDLNADHAASHLGKAQGIATLLRSIPLAGRQQAPCIPLEVLVLHGVSQERIIRSKSDDKGVEDCIFDVASAANTHLKLARQLHDKVPPQVRKIFLSAVATDAYLERLRRANFLLTHKSCVGRDTLLPARLFWKSLLNRF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : : .. : . :*:.::.* ***.:**:**:* : :. ********::: :.. . *. **::**:.:::. : :. *** ** ::* :.*.: :: ::: **: :*:..:::** * *:* .*** * ** *:::::*******:****** * **: * . :: :*::: : **.*** ::* . *:.:.* ::*:** *: **: **.: ** .. **.:* : :*:::::.:* : * * :: ** *: :* : :", "identical_positions": 93, "similar_positions": 110, "identity": "27.19%" }, { "cls_id": "homologset.agr.RGD:1309086", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P25918-1", "uniprot_id": "CD19_MOUSE", "id": "P25918-1", "name": "B-lymphocyte antigen CD19", "aln": "-----------------------------------------------MPSPLPVS----FLLFLTLVGGRPQKSLLVEVEEGGNVVLPCLPDSSPVSSEKLAWYRGNQSTPFLELSPGSPGLGLHVGSLGILLVIVNVSDHMGGFYLCQKRPPFKDIWQPAWTVNVEDSGEMFRWNASDVRDLDCDLRNRSSGSHRSTSG----SQLYVWAKDHPKVWGTKPVCAPRGSSLNQSLINQDLTVAPGSTLWLSCGVPPVPVAKGSISWTHVHPRRPNVSLLSLSLGGEHPVREMWVWGSLLLLPQATALDEGTYYCLRGNLTIERHVKVIARSAVWLWLLRTGGWIVPVVTLVYVIFCMVSLVAFLYCQRAFILRRKRKRMTDPARRFFKVTPPSGNGTQNQYGNVLSLPTSTSGQAHAQRWAAGLGSVPGSYGNPRIQVQDTGAQSHETG-----LEEEGEAYEEPDSEEGSEFYENDSNLGQDQVSQDGSGYENPEDEPMGPEEEDSFSNAESYENADEELAQPVGRMMDFLSPHGSAWDPSREASSLGSQSYEDMRGILYAAPQLHSIQ--SGPSHEEDADSYENMDKSDDLEPAWEGEGHMGTWGTT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1LNH2-1", "uniprot_id": "F1LNH2_RAT", "id": "F1LNH2-1", "name": "", "aln": "MWGLPQPSQTPMVHCPLGSCLPQHPLRSRAEAGCPREPGYHAISSPCLPPPLPYLSRRQAPEFLTGGGRRGWGSPFPLPTEGDNVVLSCLRDSSPVSSEKLAWYRGNQSTPFLELSLRSPDLGLHIGPLGILLVIVNVSDHRGGFYLCQKRPSFKDTWQPAWTVNVEDSGELFRWNASDLGDLDCDLGNRSSGSHRSTSG----SQLYVWATDHPEVWKTKPVCAPREISLNQSLINQDLTVAPGSTLWLSCGVPPVPVTKGSISWTHVHPKTLNVSLLSLSLGGEHPVREMWVWGSLLLLPQAKASDEGTYYCLQGGLTIKMHVKVIARSAVWLWLLRTGGWIVPVVTLVYVIFCMVSMAAFLYFRRAFILRRKRKRMTDPARRFFKVTPPSGNGTQNQYGNVLSLPTSTSGQAHAQRWAASLGSGPVSYGNPRIEVQDAGAQRHETG-----LEEEGEAYEEPDSEEGSEFYENDSNLEQDQLSQDGSGYENPEDDPVGPEEEDSFSNAESYENADEELAQPVGRTMDFLSPHGSAWDPSREASSLGSQSYEDMRGILYAAPQLQSIR--SGPSHEEDADSYENMDKSDDPEPAWAGEGHMGTWGAT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P15391-1", "uniprot_id": "CD19_HUMAN", "id": "P15391-1", "name": "B-lymphocyte antigen CD19", "aln": "-----------------------------------------------MPPPRLLF----FLLFLTPMEVRPEEPLVVKVEEGDNAVLQCLKGTSDGPTQQLTWSRESPLKPFLKLSLGLPGLGIHMRPLAIWLFIFNVSQQMGGFYLCQPGPPSEKAWQPGWTVNVEGSGELFRWNVSDLGGLGCGLKNRSSEGPSSPSGKLMSPKLYVWAKDRPEIWEGEPPCLPPRDSLNQSLS-QDLTMAPGSTLWLSCGVPPDSVSRGPLSWTHVHPKGP-KSLLSLELKDDRPARDMWVMETGLLLPRATAQDAGKYYCHRGNLTMSFHLEITARPVLWHWLLRTGGWKVSAVTLAYLIFCLCSLVGILHLQRALVLRRKRKRMTDPTRRFFKVTPPPGSGPQNQYGNVLSLPTPTSGLGRAQRWAAGLGGTAPSYGNPSSDVQADGALGSRSPPGVGPEEEEGEGYEEPDSEEDSEFYENDSNLGQDQLSQDGSGYENPEDEPLGPEDEDSFSNAESYENEDEELTQPVARTMDFLSPHGSAWDPSREATSLGSQSYEDMRGILYAAPQLRSIRGQPGPNHEEDADSYENMDNPDGPDPAWGGGGRMGTWSTR", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*.* *** * . . **.*.** ** .:* .:::*:* * . .***:** *.**:*: .*.* *.*.***:: ******* *. :. ***.******.***:****.**: .*.*.* **** . *.** .:*****.*:*::* :* * * ****** ****:************** .*::*.:*******: *****.* .::*.*:*** : ****:*.* * *.*** :*.**:. *::: **..:* ******** *..***.*:***: *:..:*: :**::***********:*********.*.*.************.*** .:******.**. . ***** :** ** .: *****.********.********** ***:************:*:***:************ ****:***.* *****************:********************:**: .**.************:.*. :*** * *:****.: ", "identical_positions": 341, "similar_positions": 118, "identity": "55.99%" }, { "cls_id": "homologset.agr.RGD:1309087", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZVD5-1", "uniprot_id": "D3ZVD5_RAT", "id": "D3ZVD5-1", "name": "Transforming growth factor beta activator LRRC32", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSYQILILLAMLTLG-LAISQRRDQVPCRTVNKEALCHGLSLLQVPSVLSLDIQA-------------------LYLSGNRLQSILVSPLSFYTALRHLDLSDNEISFLQPGVFQALPYLEHLNLAHNRLAAG------------------------------------MALNSGGLGRLP--------------------------------LVVSLDLSGNSLHGSLVERLLGEAPRLRTLSLAENSLTRLARHTFWGMPAMEQLDLHSNVLMDIEDGAFEALPQLTHLNLSRNSLTCISDFS---LQQLQVLDLSCNSIETFQTAPES-QAQFQLAWLDLRENKLLHFPDLAMFPRLIYLNVSNN-----------------LIQLPTG-LPQDSEDLHAPSEGWSASLLSNPSRNASI----HPLSQLLNLDLSYNEIELVPAGFLEHLTSLRFLNLSRNCLRSFEARRAGSLPCLVLLDLSHNVLEALELGTK-VLGSLKTLLLQDN-----------------------------TLRELPPYTFAGLASLQRLNLQGNQVSPCG---------------------------------------GQAEPGPPGCVDFSGIPTLHFLNMAGNSMETLR---------------AGSFLHTP----------LTELDLSANPGLDVATGALVGLEAS-LEVLELQGNGL-------------------------VVLRVDLPCFRRLKRLNLAENRLSHLP-------------------------------------------------------------------------------------------------AWTRAVSLEVLDLRNNSFSLLPGNAMGGLETSLRRLYLQGNPLSCCGNG----------------------------------------------------------------------------------------------------------------------------------------------------------WLAAQLHQGRVDVDATQDLICRFGS----------------------------------QEEVSLSLVRPEDCE---------------------------------------------------------------------KGGLKN-----------VNLIIILSFTLVSAIVLTTLATCCFLRRQKLSQQYKA-----------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "G3XA59-1", "uniprot_id": "LRC32_MOUSE", "id": "G3XA59-1", "name": "Transforming growth factor beta activator LRRC32", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSHQILLLLAMLTLG-LAISQRREQVPCRTVNKEALCHGLGLLQVPSVLSLDIQA-------------------LYLSGNQLQSILVSPLGFYTALRHLDLSDNQISFLQAGVFQALPYLEHLNLAHNRLATG------------------------------------MALNSGGLGRLP--------------------------------LLVSLDLSGNSLHGNLVERLLGETPRLRTLSLAENSLTRLARHTFWGMPAVEQLDLHSNVLMDIEDGAFEALPHLTHLNLSRNSLTCISDFS---LQQLQVLDLSCNSIEAFQTAPEP-QAQFQLAWLDLRENKLLHFPDLAVFPRLIYLNVSNN-----------------LIQLPAG-LPRGSEDLHAPSEGWSASPLSNPSRNAST----HPLSQLLNLDLSYNEIELVPASFLEHLTSLRFLNLSRNCLRSFEARQVDSLPCLVLLDLSHNVLEALELGTK-VLGSLQTLLLQDN-----------------------------ALQELPPYTFASLASLQRLNLQGNQVSPCG---------------------------------------GPAEPGPPGCVDFSGIPTLHVLNMAGNSMGMLR---------------AGSFLHTP----------LTELDLSTNPGLDVATGALVGLEAS-LEVLELQGNGL-------------------------TVLRVDLPCFLRLKRLNLAENQLSHLP-------------------------------------------------------------------------------------------------AWTRAVSLEVLDLRNNSFSLLPGNAMGGLETSLRRLYLQGNPLSCCGNG----------------------------------------------------------------------------------------------------------------------------------------------------------WLAAQLHQGRVDVDATQDLICRFGS----------------------------------QEELSLSLVRPEDCE---------------------------------------------------------------------KGGLKN-----------VNLILLLSFTLVSAIVLTTLATICFLRRQKLSQQYKA-----------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14392-1", "uniprot_id": "LRC32_HUMAN", "id": "Q14392-1", "name": "Transforming growth factor beta activator LRRC32", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRPQILLLLALLTLG-LAA-QHQDKVPCKMVDKKVSCQVLGLLQVPSVLPPDTET-------------------LDLSGNQLRSILASPLGFYTALRHLDLSTNEISFLQPGAFQALTHLEHLSLAHNRLAMA------------------------------------TALSAGGLGPLP--------------------------------RVTSLDLSGNSLYSGLLERLLGEAPSLHTLSLAENSLTRLTRHTFRDMPALEQLDLHSNVLMDIEDGAFEGLPRLTHLNLSRNSLTCISDFS---LQQLRVLDLSCNSIEAFQTASQP-QAEFQLTWLDLRENKLLHFPDLAALPRLIYLNLSNN-----------------LIRLPTG-PPQDSKGIHAPSEGWSALPLSAPSGNASG----RPLSQLLNLDLSYNEIELIPDSFLEHLTSLCFLNLSRNCLRTFEARRLGSLPCLMLLDLSHNALETLELGAR-ALGSLRTLLLQGN-----------------------------ALRDLPPYTFANLASLQRLNLQGNRVSPCG---------------------------------------GPDEPGPSGCVAFSGITSLRSLSLVDNEIELLR---------------AGAFLHTP----------LTELDLSSNPGLEVATGALGGLEAS-LEVLALQGNGL-------------------------MVLQVDLPCFICLKRLNLAENRLSHLP-------------------------------------------------------------------------------------------------AWTQAVSLEVLDLRNNSFSLLPGSAMGGLETSLRRLYLQGNPLSCCGNG----------------------------------------------------------------------------------------------------------------------------------------------------------WLAAQLHQGRVDVDATQDLICRFSS----------------------------------QEEVSLSHVRPEDCE---------------------------------------------------------------------KGGLKN-----------INLIIILTFILVSAILLTTLAACCCVRRQKFNQQYKA-----------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q0KHN6-1", "uniprot_id": "Q0KHN6_DROME", "id": "Q0KHN6-1", "name": "Chaoptin", "aln": "MCRGRNLRTSAALVNLLAKCTKSTNGQAAVLAKDKESENRENLVPQKQRAQRQNKQQQHPQQYPQMMQQQQQQQQQQRQEQHQEQHNQRQQQGRQIEQMAMGTNAEAAAAKKHKHQTKPTDSECEGKHKHKRNRNNVAGVQQHVLRLKLELQLLLCALLPTALLLGLLPLPPGAAATAMISSAKGSVRELLLTEMGGGGVGVGVGGSSGGAAHPAGGGPGTGLAGGDGGGAAGIECPSFDNTACPCYKFEDGLFLECPGTTAISLRSTLERISAPIHSLSIYDFDRSVTSLSQDVFQPGVHIRHLQFSHSHLEALKDNSLRNVRSSLESLSIVNGKLTQMPSRALSSMQKLTALDFDYNEIVRVDDYSFYGLRISKLNMKGNRLQGMPEHAFAGLEECMQEIDVSENGLRTFPLMALRKLDHLRILRLSNNRIPTFYGDIQLATNNASAAAAAVGAFQLPSLIFLDLSSNQFAEIGPDCFRAFPQLKTLSFYANQIELVQPEAFKSLRELMSLDMSHNRIIGLDPKVFEKNKRLQTVDLSHNHIHTIGGVFSNLPQLREVFLSENNILELPADAFTNSTNVDVIYLESNAIAHIDPNVFSTLVNLDHLYLRSNFIPLLPVTLFDKSTKLTSLSLDNNEIQDLEIG-MFRKLEHLREVRLHNNRIRRVRRGVFEPLPSLQELHIQKNSIEDIEPQAFHTLENMQHINLQDNQLTVLEDIFPDENSSLLSVQLEANYLHKVHPRTFSRQQKVQIMWLKDNQLTRVERSFFADTPQLGRLYLSDNKIRDIEKDTFVNLLLLQFLDLSGNQLRQLRRDYFAPLQDLEELSLARNHIEAIEGYAFAKLKNLKSLDLSHNPLVQLTRDIFSNEFPLNSLNLGNCSLRKLEQHAFKSLTNLNELNLERNQLNPADIQTL-DIPNLRRLLLSHNNFSYAGSVGIMAGMLDRLRSLQQLSMSNCSLGQIPDLLFAKNTNLVRLDLCDNRLTQINRNIFSGLNVFKELRLCRNELSDFPHIALYNLSTLESLDLARNQLASIDFFKLSGTLNLRQLILRDNKITALSGFNAVNLTQLDSVDLSGNLLLSLPANFLRHSINLQKVHLSNNRFLQIPSSALSDVSIPRLSWLNLTGNPINRIYTVKEERYPYLKELYICQTNLSILTSKDFEAFQALQHLHLVNNRITRISPGAFKSLTNLLTLDLSVNELEMLPKERLQGLRLLRFLNISHNTLKDLEEFSVDLLEMQTLDLSFNQLDRISKKTFRNLHGLLELFLMGNRMTVLSNDAFRFLRKLHVLDLRKNYFELVPLEPLRPLETNLRTLRLEENPLHCSCDAQKLWEWLRDHRKWSLSMGSGAGRGIGGLTGGLGGDSINYLRCEHPTELRGKVFGRMEPQQFCDAPLIPKMAIQDIQPYSVVVSWQSRDHLGLNGFEIVYHATGDGLVTAGSPTSRERDSLRDIHDPERQRTRDQARERSRERDRDRERDRERFSIATDEIHGKRLNGTASSTKLTKLSPNTRYHICVIGSGNWLSEPLANALQRLHTNESLREEEAVMMSAPLPESFSPYQHQHNRNSNGNANPAMVQDHNKKQNPDQDLDNVVGQDNALMEVLKNSHISACTDVQTLDSTPSLVTDENGLSSNGFIHSILTRRLGLIVGCCLGIIVFIVMISVLSYVKLKKKRIENAKRQAALPPEYISYRHFSIPNEELTRTAANAGTVAAAAAANNSHNSNNSTDEGSSPHMSSVPSGISAHISGTSLSTGGTGTGSTTTTATTPIGGVPLGKAGSTLVGVGLVVADSSVDVGYAHNHAHAHAHRHMAAGVVLNTNHLSVC", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VV09-1", "uniprot_id": "Q9VV09_DROME", "id": "Q9VV09-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNRTRRILEVIVILILAISSCDGSGGDIPLRCDEYDSMG----YMDVNEAFCTVTG----------------------FTVTHSQNVVIKNIPPGNMVKFMKFYESTLLYMPFHLFETFPYLKTLDVSN---------------------------------------------------------------------------------------TNILELTRN---------AFSAASNLTYLNLAYNNLTSIQTSVFIGANVLMRLDLSYNEISSLSVNAFCGLHTISQIYLTGNLLKELHNDIFKDNEYLEKVSFEGNLLTSIQPEVFRNMRRIKEVNLSNNRLIFIHPDTFADAASLENLVLSYN---------------------------ELKNFQLTEKNIVHQLHLDNNYLTNLT---------INATRFVRASHNQISELFLHQSLHIETLDLSANKLSSISN--ITNITHMLYLDVSDNPIGPLNISTFSQLKRLRGLNLRGT-----------------------------GIRELKFGMFSKQKYLEELDLSFNNLTILN-----------------------------------------------LDMFVPYLTNLKKFLIDGNGLTELQ----------------G-----------------NRTFSEAFPQLQKLGVSRNRFNCSYLHHLLIP------------------------------------PSLPESVVLNIEPDTNLDET---------------------------------------------------------------------------------------------------PHIRDVSCISQSQEVVNASFTAEESKLESQIQMLSKQLDIVGSHSKN-------------------------------------------------------------------------------------------------------------------------------------------------------------LELHLAFMQIFAYVMGGLVLVG------------------------------------VVSLITLRYLKNQ---------------------------------------------------------------------RSGRYD-------------------RSSIVFRSNATMEANLTLGSEDLQ----------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : :* *. .: : . ::: . : : .: . : . : : :.: . : : *: *: :.::: *.* * : * : * * : : .* : .*.: * : .:. ** * : :: * * *. : : . * :.:. * : .:. ..: *. .. :. :* . * * :* * . . : : * : : :. :: : : *:*. * .:. .:. : *::. * : . :: : : *: * * . : :: *: * .*:* *.:: . . .. .*: : : .* : * * . . *: : .. . * * : .: *:: : . .: :. :: .. **:.:: * : : : . . ::* :: * : : : . . ..* . : :: : : : :. ", "identical_positions": 56, "similar_positions": 176, "identity": "3.08%" }, { "cls_id": "homologset.agr.RGD:1309088", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M6K1-1", "uniprot_id": "A0ABK0M6K1_RAT", "id": "A0ABK0M6K1-1", "name": "", "aln": "MVGVPG------------------AAAFQLGCEKRVPAMPGSPVEVKIQSRASPPIMPPLPPINPGGPRPVSFTPTALSNGISHSP------------------------------------------------------------------------------PTLNGAPS-----------PPQRFSNGPASSTSSALTNQQLPATCGARQLSKLKRFLTTLQQFGNDIS-PEIGEKVRTLVLALVNSTVTIEEFHCKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARAAKQTPSQYLAQHEHLLLNTS--IASPADSSELLMEVHGNGKRPSPESFFYRRDENNF-ERDTVPPEPTAKRVCTISPAPRHSPALTVPLLSAGGQFHPTPPPLQHYTLEDIATSHLYREPN--KMLEHREVRERHHNLSLNGGYQDELVDHRLTEREWADEWKHLDHALNCIMEMVEKTRRSMAVLRRCQESDREELNYWKRRCNENTELRKTGTELV----SRQHSPGSTDSLSNDSQREFTSRPAAGYVPVEFWKKTEEAVNKVKIQAMSEVQKAVAEAEQKAFEVIATERARMEQTIADVKRQAAED--------AFLVINEQEESTENCWNCGRKASETCSGCNIARYCGSFCQHKDWERHHRLCG--QSLHGHSPHSQSRSLLPGGRGS-ARSADCSVPSPALDKTSATTSRSSTPASVTAIDANGL-----------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70374-1", "uniprot_id": "MTG8R_MOUSE", "id": "O70374-1", "name": "Protein CBFA2T2", "aln": "MVGVPG------------------AAAFQLGCEKRVPAMPGSPVEVKIQSRSSPPIMPPLPPINPGGPRPVSFTPTALSNGINHSP------------------------------------------------------------------------------PTLNGAPS-----------PPQRFSNGPASSTSSALTNQQLPATCGARQLSKLKRFLTTLQQFGNDIS-PEIGEKVRTLVLALVNSTVTIEEFHCKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARAAKQTPSQYLAQHEHLLLNTS--IASPADSSELLMEVHGNGKRPSPE----RRDENNF-ERDTVPPEPPAKRVCTISPAPRHSPALTVPLMNPGGQFHPTPPPLQHYTLEDIATSHLYREPN--KMLEHREVRERHHNLSLNGGYQDELVDHRLTEREWADEWKHLDHALNCIMEMVEKTRRSMAVLRRCQESDREELNYWKRRFNENTELRKTGTELV----SRQHSPGSTDSLSNDSQREFTSRPATGYVPVEFWKKTEEAVNKVKIQAMSEVQKAVAEAEQKAFEVIATERARMEQTIADVKRQAAED--------AFLVINEQEESTENCWNCGRKASETCSGCNIARYCGSFCQHKDWERHHRLCG--QSLHGHSPHSQSRPLLPGGRGS-ARSADCSVPSPALDKTSATTSRSSTPASVTAIDANGL-----------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43439-1", "uniprot_id": "MTG8R_HUMAN", "id": "O43439-1", "name": "Protein CBFA2T2", "aln": "MAKESGISLKEIQV---------LARQWKVGPEKRVPAMPGSPVEVKIQSRSSPPTMPPLPPINPGGPRPVSFTPTALSNGINHSP------------------------------------------------------------------------------PTLNGAPS-----------PPQRFSNGPASSTSSALTNQQLPATCGARQLSKLKRFLTTLQQFGNDIS-PEIGEKVRTLVLALVNSTVTIEEFHCKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARAAKQTPSQYLAQHEHLLLNTS--IASPADSSELLMEVHGNGKRPSPE----RREENSF-DRDTIAPEPPAKRVCTISPAPRHSPALTVPLMNPGGQFHPTPPPLQHYTLEDIATSHLYREPN--KMLEHREVRDRHHSLGLNGGYQDELVDHRLTEREWADEWKHLDHALNCIMEMVEKTRRSMAVLRRCQESDREELNYWKRRYNENTELRKTGTELV----SRQHSPGSADSLSNDSQREFNSRPGTGYVPVEFWKKTEEAVNKVKIQAMSEVQKAVAEAEQKAFEVIATERARMEQTIADVKRQAAED--------AFLVINEQEESTENCWNCGRKASETCSGCNIARYCGSFCQHKDWERHHRLCG--QNLHGQSPHGQGRPLLPVGRGSSARSADCSVPSPALDKTSATTSRSSTPASVTAIDTNGL-----------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A7B7-1", "uniprot_id": "A0AB13A7B7_DANRE", "id": "A0AB13A7B7-1", "name": "", "aln": "MVGIPG--------------------AFQYSAEKKVPAMPGSPVDAKTHSRPTVSVMPPLPSVNPSGPRPAAFSTTALTNGINHSP------------------------------------------------------------------------------PMLNAIPS-----------PPQRYSNGPSSSSSSSLANQQLPATCGARQLSKLKRFLTTLQQFGNDIS-PEIGESVRNLVLALVNSTVTIEEFHSRLQEATNFPLRPFVIPFLKANLPLLQRELLHCARAAKQTPAQYLSQHEHLLLSTT--VPSPADSSELLLEPS-DSKRHSPN----RSKENGFHDRPPASLEPPAKRICTISPAPRHSPAHPLQLP---AQIHPTPPPLQHYALEDISSAQLYREPQ--RILELKE---RPRLTGSNGGYREEPVDHRLTEREWAEEWRHLDHVLNSIVDMVEKTRRSVSVLRRCQESDREELNFWRRRSNPHDEGRKNGNTPVNIPFSKTHSPLSAEGVNADSPRDVPLRASSGYVPDEIWRKAEEAVNEVKRQAMDEVQKAVAEAEQKAFEMITAERAKMEKTLAEAKRKATED--------AIQVINEQEDSSECCWNCGRKASETCSGCNAARYCGSFCQHKDWERHHLICS--PGLQNQ-PKTMSR-----------SQAKTPIPSPSLEKNSSRASTPSTPASASTPDTSAH-----------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KEZ2-1", "uniprot_id": "A0A0B4KEZ2_DROME", "id": "A0A0B4KEZ2-1", "name": "", "aln": "MMALDGKAIIKEEITDKDAYDAAAAAAAAVAAGAALAVASAAAVQVPPASSSSAGSASSAAAAATNNTTSAAATAAAISRRLKASSSGGDKSSTSSSSSKDSSHTSSSRSERDRERERERERERDRLCRTPPDSPPDSSRSLAPRSPHSPLQLHQHPQRNASVSPVVNGSSSGGGGVGSSGTSPTPTPGSQHAASLAAAAAAAAAAHVEQARLVSKMRKFLGALVQFSQELGQPEVCERVRALVLSLCSGSISVEEFRLALQEAINLPLRPYVVPLLKNSIALVQREILALARATNQSALQYVTNNEQAVMEFAPHGVASAEFGDIFIQLEAPTSNGSSAVFKRRSSDSMMEHGGHNGLQEWNEYMASGGAGYPPPPSKRLTLHPAHSVVAYGEYGVSSAEGLPSAAAFMQRDERDLRMSEAQARHAAPPQRAGNPQPNPNAAAPGAPGAGGEEEWKNIHTMLNCISAMVDKTKRAITILQQRG--------------------------------IEPQHPNSGQEVTPAAMAELRR--QTEEKVAEFKRNAEDAVTQVKRQAVIEIQRAVVAAETRAAEIMTQERLRMEKFFMEMSRHSSGERDLDNKSPSMASAQNGSNLQQQCWNCGRKATETCSGCNMARYCSASCQYRDWDSHHQVCGNTRASELSAKHLHSASNLSLRNAMATRSPPTPNSAAHLQAAAAAAAAAAGAREAVSAPVGGPGAGIAVGTGAGSGGQSGGGGGGGGGGGGGAAAAAVAAATPGALVANGLGSKXRIRMMKPKKKYLC", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * . :.. ..:.*:. * .: .. .. .... ..: :.:*::. :. *. * :*. .* *. .. ::* ::: : . . ** :**:::** :* **.:::. **: * ** ***:* ..::::***: **** *:****:*:*:** .:.*:***:* ***::*:. **::::*: ::. : :.*: .::::: .. *. * .:. : . : : :.: ... .*: : * . . :. ::: : *: . :: * : . * . : . . :**:::. **.* **:**:*::::*:: . : * * : :. : :. : *: :::*:**.:** **: *:*:**. ** :* *::: ** :**: : : .*::: : :: :: .: : ********:******* ****.: **::**: ** :*. . : . .. . .:. *: :: :: .: . .. : ... ", "identical_positions": 126, "similar_positions": 218, "identity": "15.93%" }, { "cls_id": "homologset.agr.RGD:1309089", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5BJT6-1", "uniprot_id": "LSG1_RAT", "id": "Q5BJT6-1", "name": "Large subunit GTPase 1 homolog", "aln": "-----MGRRRAPGGGS-LGRVLIRHQTQRS-RSHRHTDSWLHTSELNDG--------YDWGRLNLQSVTEQSSLEDFLATAELAGTEFVAEKLN-IKFVPPEARTG-------LLSFEESQRIKRLHEENRQFLCIPRRPNWDRKTSPEELKQAEKDNFLKWRRQLVRLEE-EQKLILTPFERNLDFWRQLWRVIERSDIVVQIVDARNPLLFRCEDLECYVKEIDAAKENVILINKADLLTAEQRVAWAVHFEKEGVKVIFWSALAETVHLNGDSKDEVNSVAGEANSSESEDSSLDGNEIPH--------RDLFLLSEESESDDDDSEYEDCQE---DEEEDWQTCSEEDSNPEEGQEEGGCDRDQKEHGPEDSEAQSRASPENSQMSNKSHLVSKQELLELFKKLHTGKKVKDGQLTVGLVGYPNVGKSSTINTIMGNKKVSVSATPGHTKHFQTLYVEPGLCLCDCPGLVMPSFVSTKAEMICSGILPIDQMRDHVPPVSLVCQNIPRRVLEATYGINIIKPGEDEDPY-RPPTSEELLTAYGCMRGFMTA-HGQPDQPRSARYILKDYVRGKLLYCHPPPGKDPVA------FQHQHRQLLENKIKGEELRLQPGKTQKAKQVENVVDKTFFHQENVRALTKGVQAVMGYKPGSGLVTAAAASAENVPG-----------------------KPWKKHGNRNKKEKSRRLYRHLDV-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UM18-1", "uniprot_id": "LSG1_MOUSE", "id": "Q3UM18-1", "name": "Large subunit GTPase 1 homolog", "aln": "-----MGRRRAPGGGS-LGRVLIRQQTQRS-RSHRHTDSWLHTSELNDG--------YDWGRLNLQSVTEQSSLEDFLATAELAGTEFVAEKLN-IKFVPPEARTG-------LLSFEESQRIKKLHEENRQFLCIPRRPNWDRKTSPEELKQAEKDNFLKWRRQLVRLEE-EQKLILTPFERNLDFWRQLWRVIERSDIVVQIVDARNPLLFRCEDLECYVKEIDAAKENVILINKADLLTAEQRFAWAVHFEKEGVKVIFWSALAETDHLNGDLKEEVDSVAGDTNKTESESSSLDANEIPH--------RDLISLSEESASDSGDSKYEDCQE---DEEEDWQTCSEEDSVPE---EEEGCN--------ADSETQNRKNAENQQVNNDSYLVSKQELLELFKKLHTGKKVKDGQLTVGLVGYPNVGKSSTINTIMGNKKVSVSATPGHTKHFQTLYVEPGLCLCDCPGLVMPSFVSTKAEMICNGILPIDQMRDHVPPVSLVCQNIPRRVLEVTYGINIIKPREDEDPY-RPPTSEELLTAYGCMRGFMTA-HGQPDQPRSARYILKDYVGGKLLYCHPPPGKDPVA------FQHQHQQLLESKVKGGELRLQPGKGRKAKQIENVVDKTFFHQENVRALTKGVQAVMGYKPGHGLVTAAAASAENVPG-----------------------KPWKKHGNRNKKEKSRRLYKHLDV-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H089-1", "uniprot_id": "LSG1_HUMAN", "id": "Q9H089-1", "name": "Large subunit GTPase 1 homolog", "aln": "-----MGRRRAPAGGS-LGRALMRHQTQRS-RSHRHTDSWLHTSELNDG--------YDWGRLNLQSVTEQSSLDDFLATAELAGTEFVAEKLN-IKFVPAEARTG-------LLSFEESQRIKKLHEENKQFLCIPRRPNWNQNTTPEELKQAEKDNFLEWRRQLVRLEE-EQKLILTPFERNLDFWRQLWRVIERSDIVVQIVDARNPLLFRCEDLECYVKEMDANKENVILINKADLLTAEQRSAWAMYFEKEDVKVIFWSALAGAIPLNGDSEEEANRDDRQSNTTKFGHSSFDQAEISHSESEHLPARDSPSLSENPTTDEDDSEYEDCPE---EEEDDWQTCSEEDGPKE-----EDCSQDWKESSTADSEARSRKTPQKRQIHNFSHLVSKQELLELFKELHTGRKVKDGQLTVGLVGYPNVGKSSTINTIMGNKKVSVSATPGHTKHFQTLYVEPGLCLCDCPGLVMPSFVSTKAEMTCSGILPIDQMRDHVPPVSLVCQNIPRHVLEATYGINIITPREDEDPH-RPPTSEELLTAYGYMRGFMTA-HGQPDQPRSARYILKDYVSGKLLYCHPPPGRDPVT------FQHQHQRLLENKMNSDEIKMQLGRNKKAKQIENIVDKTFFHQENVRALTKGVQAVMGYKPGSGVVTASTASSENGAG-----------------------KPWKKHGNRNKKEKSRRLYKHLDM-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NY89-1", "uniprot_id": "LSG1_DANRE", "id": "Q6NY89-1", "name": "Large subunit GTPase 1 homolog", "aln": "-----MGKKKTRGEGSGLGRALIKERLNAG-RGYRRNDTWLHTSELNDG--------YDWGRLNLQSVTEQSSLDDFLATAELAGTEFVAEKLN-IKFVPAEARAG-------LLSSEESRRLKKLHEENKQLLRIPRRPPWDESTSPEVLQQTEKDSFLTWRRDLARLEE-EQKLILTPFERNLDFWRQLWRVIERSDVVVQIVDARNPLLFRCPDLEKYVKEVSVHKVNMLLLNKADLLTREQRRAWARYFQKEGIRAVFWSALAEAQRLEAEERGEDAMDQEDQSDTEEETASKNATDHHE--------ENSSSPNEEKDENEQDEEEEGEDERICVDESEWQTCSEESGDED-------------------HAEENPESTATSSFYNSSRLLRKNELLEMFKSVHSGPTCKDGQITVGLVGYPNVGKSSTINTIFRNKKVSVSATPGHTKHFQTLFVEPGLCLCDCPGLVMPSFVSTKAEMICSGILPIDQMRDHVPAISLVCQNIPRNVLEGTYGINIIRPREDEDPD-RPPTYEELLMAYGYMRGFMTA-HGQPDQSRSARYVLKDYVSGKLLYCHPPPHINPED------FQPQHAKFAMRITGAEQIDGSGGKPSKVKRIENTVDKQFFHQANVRALTKGVQMVMGYKPGSGPVEAGKANTEQQAG-----------------------KPWKKHGNRNKKEKVRRLNKHLDA-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W590-1", "uniprot_id": "LSG1_DROME", "id": "Q9W590-1", "name": "Large subunit GTPase 1 homolog", "aln": "-----MGKKNKGGAPN-LGRQLIKDRFGHTQRRKVDNDTMLHTTELQDG--------YDWGRLNLSSVTEESSFQAFLRTAELAGTEFQAEKLN-ITFVNPKQRVG-------LLSKTQEQRMHQKHDEHRDQLKIPRRPKWTKETSAEELVRAENEAFLDWRRDLALLQE-DEEILMTPYEKNLEFWRQLWRVVERSDVVVQIVDARNPLLFRSADLERYVKEVEPSKMNMILVNKSDLLTEEQRRHWAEYFDSEGIRTAFYSATLVEEELKREAEECLDSFP------EVQQLRRAVEEIKQ--------------SLDSVEDALN-----------VIEQKYKTIP---------------------------ETQNDELPRLPGDKNSPRLLSRLELIEFLRNIYTGPRHTEQHVTVGMVGYPNVGKSSTINSLMTVKKVSVSATPGKTKRFQTLFLDKDILLCDCPGLVMPSFVLTKADMLLNGILPIDQMRDHVPAVNLLCERIPRHVLEDKYGIVIAKPLEGEDME-RPPHSEELLLAYGYNRGFMTS-NGQPDQARSARYVLKDYVNGRLLYAMSPPSVPQTE------YHTFPERQRRVIEESQLPGQQQRAMRINKSTSKELDNQFFSDKPTHAHVKGRTNFPNVRLAN---DGSLVAGNDPAA-----------------------KPWR-HVKKERREKLRKKFSHLDEH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53145-1", "uniprot_id": "LSG1_YEAST", "id": "P53145-1", "name": "Large subunit GTPase 1", "aln": "MPPKEAPKKWKAPKGPKPTHRKNKNKLELGRAIKYARQKENAIEYLPDGEMRFTTDKHEANWVKLRSVTQESALDEFLSTAALADKDFTADRHSNVKIIRMDSGNDSATSQGFSMTNEQRGNLNAKQRALAKDLIVPRRPEWNEGMSKFQLDRQEKEAFLEWRRKLAHLQESNEDLLLTPFERNIEVWKQLWRVVERSDLVVQIVDARNPLLFRSVDLERYVKESDDRKANLLLVNKADLLTKKQRIAWAKYFISKNISFTFYSALRANQLLEKQKEMGEDYREQDFEEADKEGFDADEKVMEK------------------------------------------------------------------------------VKILSIDQLEELFLSKAPNEPLLPPLPG----QPPLINIGLVGYPNVGKSSTINSLVGAKKVSVSSTPGKTKHFQTIKLSDSVMLCDCPGLVFPNFAYNKGELVCNGVLPIDQLRDYIGPAGLVAERIPKYYIEAIYGIHIQTKSRDEGGNGDIPTAQELLVAYARARGYMTQGYGSADEPRASRYILKDYVNGKLLYVNPPPHLEDDTPYTREECEEFNKDLYVFDRLPDTRKEQVQNAAKAKGIDIVDLARDLNQLTFSAHTGGDTQKEAKSVTHGGKQAALYNAAEDLDRDFFKMNNVEGRLSTPFHKVQNSSAGKRHNKKNKSKNAKSKVFSIENN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : :.: :. * ** :: . ::* ***::*::: ** ** **..:* *:: . :.:: . . :: : .:: : . * :**** * . : * : *:: ** ***.*. *:* ::.:::**:*:*::.*:*****:****:**************. *** **** . * *::*:**:**** :** ** :* .:.: *:** *: : . . . :: : :: : :.:*:*************::. ******:***:**:***: :. .: ********:*.*. .*.:: .*:*****:**:: . .*:.:.**: :* *** * ..*. * :*** **. **:** *..*:.*::**:***** *:*** .** . . * . : : * . * .. : .. : * :::: :: : :: ", "identical_positions": 171, "similar_positions": 156, "identity": "23.68%" }, { "cls_id": "homologset.agr.RGD:1309090", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZTW8-1", "uniprot_id": "D3ZTW8_RAT", "id": "D3ZTW8-1", "name": "Large ribosomal subunit protein bL27m", "aln": "---SLNSVSAFSALTALLSPTAPTALAVRSASKKTGGSSKNLGGKSRGKHYGIKKMEGHYVHAGNILGTQRQFRWHPGAHVGLGKNKCLYALEEGIVRYTKEVYVPNP--------------------------------KNSEAVNLVTSLPKGAVLYKTFVHVVPAKPEGTFKLVDML---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99N92-1", "uniprot_id": "RM27_MOUSE", "id": "Q99N92-1", "name": "Large ribosomal subunit protein bL27m", "aln": "MAAAALTLRTRAAVTALLSPTAPTALAVRHASKKTGGSSKNLGGKSRGKHYGIKKMEGHYVHAGNILGTQRQFRWHPGAHVGLGRNKCLYALEEGIVRYTKDVYVPNP--------------------------------KNTEAVDLVTSLPKGAVLYKTFVHVVPAKPEGTFKLVDML---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P0M9-1", "uniprot_id": "RM27_HUMAN", "id": "Q9P0M9-1", "name": "Large ribosomal subunit protein bL27m", "aln": "MASVVLALRTRTAVTSLLSPTPATALAVRYASKKSGGSSKNLGGKSSGRRQGIKKMEGHYVHAGNIIATQRHFRWHPGAHVGVGKNKCLYALEEGIVRYTKEVYVPHP--------------------------------RNTEAVDLITRLPKGAVLYKTFVHVVPAKPEGTFKLVAML---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q86BM8-1", "uniprot_id": "Q86BM8_DROME", "id": "Q86BM8-1", "name": "Large ribosomal subunit protein bL27m", "aln": "--MQKLTMQCLKADQPLMT-------TVRNASKKTGGSTRNKKGHARPKHRGWRVQDGHHVSEGTILATQLTTRFHPGLNVGFGRNGTLFAMEHGKVYVTCEAIDPN---------------------------------WDHTWIQRNYAGRQGQNIYKKFFNVVPENQHQRFRLVEEI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P12687-1", "uniprot_id": "RM02_YEAST", "id": "P12687-1", "name": "Large ribosomal subunit protein bL27m", "aln": "---MWNPILLDTSSFSFQKHVSGVFLQVRNATKRAAGSRTSMK-DSAGRRLGPKKYEGQDVSTGEIIMRQRGTKFYPGENVGIGKDHSIFALEPGVVRYYLDPFHPKRKFIGVALRRDLKLPSPHFEPTVRRFGRFELTNKRAAYKEENSISRKDYLAKPNILKQLEVRESKRKELQDKLSKVLRDELKLDIKDIELATSYLIRVRASLKNGYPIEDARFNSRYYLKEEERLKARRESWTNEKLSESLSKIDECSDLLNSSTSFNNKLELHQYISEQEKQALKAKLLEDLEKSQHLETKKDKNYIKALFKDACNFLTLSEEVHLRRKYLKSVFPETDSTVETKSGKKSIVSRRFDYTKNKVEVIARSRRAFLSKL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: : .: . ** *:*::.** . .: :: * : :*: * * *: * :::** :**.*:: ::*:* * * : *: : :. .:.: : . .* : ", "identical_positions": 23, "similar_positions": 42, "identity": "6.13%" }, { "cls_id": "homologset.agr.RGD:1309092", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VT04-1", "uniprot_id": "PATH_DROME", "id": "Q9VT04-1", "name": "Proton-coupled amino acid transporter-like protein pathetic", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVNIVDSGSK-------HAPQEMEQFLP----------GEGKVMYKIQPRKSDTEQALAGN--------------------------------------------------------DFDPFALRDNPHPTTDNETLTHLLKASLGTGILGMPFAFMCSGLIMGIFSTIFTAFICTHCSYVLVKCGHKLYYRT-RRTKMTFAEIAEAAFQKGP-KWCRGFAPVAKFSILFGLFLTYFGTCSVYTVIVASNFEQLISYWTGTA--------------VSLRMLICIMLVPLILIAWVPNLKYLAPVSMVANVFMGLGLGITFYYLVQDLP-PVEER-----ESVV-WSTLPQFFSITIFAMEAIGVVMPLENNMKTPQSFLGICGVLSQGMSGVTLIYMLLGFLGYLRYGSATGESITLNLPIEEWPAQTVKVLISLAVYCTFGLQFFVCLEIIWDG-IKEKCK----------------------KRPTLV-NYVLRTVLVTAAVVLAVAVPTIGPFMGLIGAFCFSILGLIFPVVIELIVHWES--GFGKYNWILWKNAIITLCGIGALVFGTQAAIKDIVKAYSNNENVGE----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "M9PEU1-1", "uniprot_id": "M9PEU1_DROME", "id": "M9PEU1-1", "name": "Amino acid transporter transmembrane domain-containing protein", "aln": "------------------------------------------------------------------------------------------------------------------------------------------MSTPENLNAPAGKPPLPPRREQLTEKGQSLSLSSFGGSAGNISGSGRKQHLSGAALARHKLKMSLKRGGPPPVATSGSGVMTTSLDQQKIPTVTAGYGENEKPKGGKGGQSKFIRSDMADVPVQ---------QAAGSTLPLVISRKKGDDSEDGNYNPFEHRKVEHPTSDLETFVHLLKGSLGSGILAMPMAFSHAGLWFGLVATFAVGTLCTYCVHILVKCAHILCRRR-KIPMMGFADVAEQAFLDGP-PALNRWSRFIRFMVNTFLVIDLLGCCCIYLVFVATNVEQVVRVYMETE--------------LSIRVWIMIVTAPLIFMCLVRNLKFLTPFSMIANILMFVGIVITFIYMFSDIPAPVERP-----GIVS-VTEWPLFFGTVIFALEGIGVVMSLENDMKNPSHFIGCPSVLNFGMGLVIALYTLVGFFGFLKYGPETQASITLNLPLEDKLAQSVKLMIAIAIFFTFTLQFYVPVTILWKG-LEHKIRP---------------------EKQNIS-EYGLRVFLVLLCGGIAVALPNLGPFISLIGAVCLSTLGMIVPATIELAVYHEDP-GYGRFNWRLWKNSGLILFGVVGFVAGTYVSIIEFHAEFSSGH--------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VTD7-1", "uniprot_id": "Q9VTD7_DROME", "id": "Q9VTD7-1", "name": "Amino acid transporter transmembrane domain-containing protein", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPVMTKNGHS-------NSAYVADHP--------------DKLELAEKGQKNKAVVAKDPD---------------------------------------------------------YNPYHHRDVEHPTTNSETLFHLLKGSLGTGILAMPNAFRNSGYITGSIGTIVIGFICTFCIHQLVKAQYELCRRK-KMPSMNYPMVAETAMGEGP-KCFRVFAPYIGTVVNTFLLIYQLGTCCVYVVFVASNIKAIVDAVADTS--------------IDVRLCMIIILLPLILINWVRNLKYLAPFSTLANAITMVSFGIICYYIFREPVTTEGKD-----AFGK-PSNFPLFFGTVLFALEAIGVILPLENEMKTPQKFGGSCGVLNVSMVLIVFLYVGMGLFGYLNYGSAVLGSITLNMPEHEVLSMCVKGMLAFAIYITHGLACYVAIDITWNDYVAKRLGA---------------------QRNALFWEYAVRTGLVLITFLLAVAIPNLELFISLFGALCLSALGLAFPALIQICTHWYNTKGFAKV-WLVLSNFVLIIVGILGLVIGTYTSLKEIVLTFSE----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VLM3-1", "uniprot_id": "Q9VLM3_DROME", "id": "Q9VLM3-1", "name": "Amino acid transporter transmembrane domain-containing protein", "aln": "------------------------------------------------------------------------------------------------------------------------------------------MEDLTPLTNLQQIPEGAPRKKKMTER------------QPLLLQSDASDYEGSRGSAARPVRSSPP------------DNTLVNVHSEDSLAASGSGDDEIG-------------------------------------------------STDKSYNPTHHRDLEHPTSNFDTLVHLLKGNIGTGILAMPDAFKNAGLYVGLFGTMIMGAICTHCMHMLVNCSHELCRRF-QQPSLDFSEVAYCSFESGP-LGLRRYSMLARRIVTTFLFITQIGFCCVYFLFVALNIKDVMDHYYK----------------MPVQIYLLIMLGPMILLNLVRNLKYLTPVSLVAALLTVAGLAITFSYMLVDLPDVHTVK-----PVAT-WATLPLYFGTAIYAFEGIGVVLPLENNMRTPEDFGGTTGVLNTGMVIVACLYTAVGFFGYLKYGEHVEGSITLNLPQGDTLSQLVRISMAVAIFLSYTLQFYVPVNIVEPF-VRSHFDT---------------------TRAKDLSATVLRVVLVTFTFLLATCIPNLGSIISLVGAVSSSALALIAPPIIEVITFYNV--GYGRFNWMLWKDVLILIFGLCGFVFGTWASLAQILNDRTH----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q4V5R4-1", "uniprot_id": "POLYP_DROME", "id": "Q4V5R4-1", "name": "Glutamate transporter polyphemus", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEPKSQDQAP-------------NRDDPDLQTEPLTIAQSITSFYM-------------------------------------------------------YNPYEKRSVEVPLTNCDAFISLLKCVIGTGILAMPLAFRCSGFVMGTVMSILLMILLTYSIHLLIADMTECCRRR-RVPQVSMPEAVRIAYEEGP-KWINCFGRAAGFMTTCVLVFGQFLLCTVYLVFVSKNFKEIGDHYIER---------------YNERYYVLVACLLLLPLFMIRRLKYLVPLNLISNFLLYAGFALIMYYLFNGLPNINDRE-----MVTPPVEWI-EFIAIAAFSLTAVGSMLVVEAHMAHPQSYLGLFGVLNLAVLFILLSNMFFGIIGYWRFGDNVHASITLNIPQDEILSQFIKVFIASGIFLSYPLNGFVVITVMFSDYENSEPR----------------------GRYRTLIEYVVRLLFLFLTGAVAIGVPNLAALTELEGAFSLSNLNLLCPALIDVFLNYN--VGYGRLMWKLIRDILLILIGLIFGIVGCTVALMQLIRDF---------------------QLTLNSM--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IQF3-1", "uniprot_id": "Q8IQF3_DROME", "id": "Q8IQF3-1", "name": "Amino acid transporter transmembrane domain-containing protein", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGDKGG-----------------------------------------------------------------------------------------------FDPYENRNVAHPISDIGAFFSLLKCVVGTGVMAIPLSFNYAGIVTGIILLVSVCFMLIHGMQMLIICMIECSRRM-QIGYATYPVAMVYSFDQGP-RFFKYISKAGRYIVDGVLAFSQFGVCVVYNVFVAATLKQLVDFYWVV---------------ADLRIYIAVIALCLIPPFQIRKLKYLVPFNILASILIYTGFSLMMYYLFVDLPPITERN-----ILFGRIDKIPLFFGIALFSITSVGVMLAVEATMAKPRHYLGWFGILDRAILLVIISYVTFGLMGYWRYGDETAGSISLNIPTDEVLSQVAKGFIAAAIFLTYPLAGFVIIDIIMNHFWNKNGD----------------------LPNAALKESILRACTVVLICITAIIAPNLGPLLSLVGALTISLLNLVFPALIEICLYYPPEYNYGKLKWVLVKDIFYVIVGILILVQGTVFSIKDMISEWGGGDTTTGGPETTAEETTANMSATLTTALTAAPPDALRFRFL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W056-1", "uniprot_id": "S36A_DROME", "id": "Q9W056-1", "name": "Proton-coupled amino acid transporter-like protein acs", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNDDIKT---------------VTVYPTTLELTTPTKSANGSNDD-------------------------------------------------------YDPHQHRELKNPTTNFQTFAHFLKASVGTGVLAMPSAFAHAGYVNGTLLTLIIGSLALYCLHILIKCMYILCKRQ-RVPYVSFSQAMNLGLKQGP-PWLRCLAPIAVPFVDGFLAFYHFGICCVYVVFIAESIKQLVDEYLVV---------------WDVRIHMCIIIVPLLLIYSIKNLKLLAPFSSAANLLLLVGFGIILYYIFEELPPLSERD-----PFVA-AGKLPTFFGTVLFALEAVGVILAIEENMATPKSFVGPCGILNSGMSIVLGLYVLLGFFGYWKYGNESEGSITLNIPQSEIPAQVVKVFFAITTWISYALQGYVTAHILWDKYLAKRFK----------------------ETRQTFYELIFRAIIVLLTFGCAVAIPDLSVFLSLVGSFCLSILGLIFPVLLQICVQYT--EGYGPFRIKLIINLLLLCFGIFGGVVGTYVSILDIIAVYK-----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VTD5-1", "uniprot_id": "Q9VTD5_DROME", "id": "Q9VTD5-1", "name": "Amino acid transporter transmembrane domain-containing protein", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRNTRRRRL-------------DQKLPFHQRLLGGVQNSFGSPLA-------------------------------------------------------NEARLSSKKDNGMSDLEAFINVLKCGFGTGCLAMPYAFLNSGWLVGLICTFALGFFVLYAMHILLHHINNLGVQH-NMPMISYRKAVELSIRKGP-SIFHFLSKPFGYLVDILLCAYHFGVDCVYVVFIAKSLKHLGDMYLWV---------------WDERLYMALIASPLILTFLIRNLKSLVPFSIISNILLLTGYCVILNYLFRDLPEFEHLH-----AIQP-LRNFPIFFGTVLFSIESVGVILSLGRSMRKPESLMGTCGVLNQGMIVVISFYAVFGFFGYWRYGENTSNSILQNMPQNDILPKLATGIFALAIFFSYALQGYVTVDIIWRNYLEPELE----------------------DRYLRTVECLLRIALVIASVLVAIQYPDFGLLLSLVGSFCLAQLGLILPGIVDICLRYE--EDYGPGKIFLIRSMLFICMGLAGGVAGTVVTLQTLYARYPVVRG-------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VX84-1", "uniprot_id": "Q9VX84_DROME", "id": "Q9VX84-1", "name": "Amino acid transporter transmembrane domain-containing protein", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDAEAPNQLEKNQTATVPRQETAE-------------GGSTGETAVGGAAAKVTK---EQDHD-----------------------------------------------------AEYHPP-------TSYLETIVHLFKGNIGPGLFAMGDAFKNGGLLVAPLLTVVIAVVSIHCQHVLVTCSKKMRDLKGDSVCADYAQTVEQCFENGP-SKLRGWSRTMGRLVDIFICVTQLGFCCIYFVFISTNLKQILQAYDID---------------MNVHLVMLLAFVPVLLSSLITNLKWLTPVSMFANVCMILGLAITLYYALKDG-LPEVEER----ALWTNGSQLALFFGTAIFAFEGIALVMPLKNAMRKPHQFERPLGVLNVGMFLVSVMFMFAGSVGYMKWGEQVGGSLTLNLG-DTILAQAVKLMVSAGVLLGYPLQFFVAIQIMWPNAKQMCGIE---------------------GRS-LLGELGFRTFMVLVTLAIAEMVPALGLFISLIGALCSTALALVFPPVIELISRSE--LNKGPGIWICVKNLVILVLALLGFFTGSYESLKQIVKHFGEEEVH------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "M9PHT8-1", "uniprot_id": "M9PHT8_DROME", "id": "M9PHT8-1", "name": "Amino acid transporter transmembrane domain-containing protein", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------MPKRDLTVLHRYFSGRLFPARTQQQQSDQKAIEAAGEMGRTLEI---------TGRQNDKSLEKNPERFTKNVTEKGAD-----------------------------------------------------PENGDPVRRRGHETSELEAATHLFKGSVGAGLFAMGDCFKNGGLAGATILLPIIAVMCVHCERMLIRGSVLAVERTPGVDFLDYPETVEKCFEHGP-RPLRKMSRVMKLIVEMFLCVTQFGFCAIYFVFITENLHQVLQQNGIV---------------ISMSMVMLITLLPAMIPSLMTNLKYISPVSLFANVALLFGLIATLTIAFSDGPMPSVGDR----HLFTGGAQLALFFGTALFSYEGIALILPLRNSMRRPEKFSTRFGVLNSTMFFTTALFIFTGFVSYVRWGEEVAGSITLNLVVEEVFSQVVKVIAALGVFLGYPIQFFVMIKILWPPLKRSNNCT---------------------QKYPITSQVCLRFFMVMMTFGVALVVPKLNLFISLIGALCSTCLAFVIPVLIDFVTRAQ--VPKALGVWSYIKNILILTVAVLGIVTGTYQSIVEIVKEFK-----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q811P0-1", "uniprot_id": "S36A3_MOUSE", "id": "Q811P0-1", "name": "Proton-coupled amino acid transporter 3", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGNVPLLREVG--------------KCQRNMFGRSTASSKGSSNSRSSS----------------------------------------------------STSPKKGPRREADALMFIQIFIHLLKSNIGTGFLGLPLAVKNAGLLVGPVSLLAIGALTVHCMDILLNCACHLTQRL-QRSFVNYEETTMYSLETCPSPWLRTHSVWGRYVVSFLLIVTQLGFCSVYFMFLADNLQQIMEEAHFTSNVCQPRQSLVMTSILDTRFYMLTILPFLILLVLIQNPQVLSIFSTLATITTLSSLALIFEYLIQ-TPHHSNLP------LVANWKTFLLFFGTAIFTFEGVGMVLPLKSQMKSPQQFP---AVLYLGMSFVIFLYICLGTLGYMKFGTDTQASITLNLP-ICWLYQSVKLMYSVGIFFTYALQFHVPAEIIVPYVVSRVSE-----------------------NWALFVDLTVRTALVCLTCFSAVLIPRLDLVISLVGSVSSSALAIIIPPLLEIATFYS----ENISCATIVKDIMISILGLLGCVLGTYQALYEMTQQTHFYMANSTRVHI------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4V8B1-1", "uniprot_id": "S36A3_RAT", "id": "Q4V8B1-1", "name": "Proton-coupled amino acid transporter 3", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGKTPLLREDG--------------RCQRNTFGGSKASSKGSSSSSSNN----------------------------------------------------TVSSKKKPRRKADALMFIQIFIHLLKSNIGTGFLGLPLAVKNAGLLVGPVSLLAIGALTVHCMDILLNCACHLTSRL-QRSFVNYEETTMYSLETCPSPWLRTHSVWGRYVVSFLLIVTQLGFCSVYFMFMADNLQQIVEEAHFTSNVCQPRQSLVMTSILDTRFYMLTILPFLILLVLVQNPQVLSIFSTLATITTLSSLALIFEYLIQ-IPHHSHLP------LVASWKTFLLFFGTAIFTFEGVGMVLPLKSQMKSPQQFP---AVLYLGMSFVIFLYICLGTLGYMKFGADTQASITLNLP-NCWLYQSVKLMYSVGIFFTYALQFHVPAEIIVPYVVSRASE-----------------------NWALFIDLTVRAALVCLTCFSAVLIPRLDLVISLVGSVSSSALALIIPPLLEIATFYS----ENISCTTIAKDIMISILGLLGCVLGTYQALYEMTQQSRFPMLNSTNVHT------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q495N2-1", "uniprot_id": "S36A3_HUMAN", "id": "Q495N2-1", "name": "Proton-coupled amino acid transporter 3", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSLLGRDY--------------NSELNSLDNGPQSPSESSSSITSE----------------------------------------------------NVHPAG-----EAGLSMMQTLIHLLKCNIGTGLLGLPLAIKNAGLLVGPVSLLAIGVLTVHCMVILLNCAQHLSQRL-QKTFVNYGEATMYGLETCPNTWLRAHAVWGRYTVSFLLVITQLGFCSVYFMFMADNLQQMVEKAHVTSNICQPREILTLTPILDIRFYMLIILPFLILLVFIQNLKVLSVFSTLANITTLGSMALIFEYIMEGIPYPSNLP------LMANWKTFLLFFGTAIFTFEGVGMVLPLKNQMKHPQQFS---FVLYLGMSIVIILYILLGTLGYMKFGSDTQASITLNLP-NCWLYQSVKLMYSIGIFFTYALQFHVPAEIIIPFAISQVSE-----------------------SWALFVDLSVRSALVCLTCVSAILIPRLDLVISLVGSVSSSALALIIPALLEIVIFYS----EDMSCVTIAKDIMISIVGLLGCIFGTYQALYELPQPISHSMANSTGVHA------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P50944-1", "uniprot_id": "AVT4_YEAST", "id": "P50944-1", "name": "Vacuolar amino acid transporter 4", "aln": "MVTNNGDGEHLGIRRNGNLRHPSN-NMKIPRRAQSTVLNSNPFYSRKYSMSTLTPRDICRSVDSRVFVDMSSPNFQTLEDPHRDEIINSVRLNYLNSSKRSSVSHGNEAIPRVNPTKNSSASTIAAANVD------SDDDETNLSSAGGDITHDIYKLVKAEDPKRLRRPRSMENVTPKIEHHTKLSSASGLN-VPGGFRREFIVNKKRQEHQLNDSASSDFTSHESDSINQSSPSSNQDIDKVPFLTRNFLEFLYVFGHFAGESFEDDFIPDSSNMMIRGEDERSALLSRPDHMKVLPSAKG--TTSTKKVFLILLKSFIGTGVLFLPNAFHNGGLFFSVSMLAFFGIYSYWCYYILVQAKSSCGVSS---------------FGDIG---LKLYGPWMRIIILFSLVITQVGFSGAYMIFTAKNLQAFLDNVFHV-------------GVLPLSYLMVFQTIIFIPLSFIRNISKLSLPSLLANFFIMAGLVIVIIFTAKRLFFDLMGTPAMGVVYGLNADRWTLFIGTAIFAFEGIGLIIPVQDSMRNPEKFP---LVLALVILTATILFISIATLGYLAYGSNVQTVILLNLPQSNIFVNLIQLFYSIAIMLSTPLQLFPAIKIIENKFFPKFTKIYVKHDDLTTRVELRPNSGKLNWKIKWLKNFIRSIIVIIVVSIAYFGSDNLDKFVSVIGSLACIPLVYIYPSMLHLRGNSLPETKGEFWRFKPMLDTILIFFGIASMLYTSYQSIFGV----------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P36062-1", "uniprot_id": "AVT3_YEAST", "id": "P36062-1", "name": "Vacuolar amino acid transporter 3", "aln": "MNGKEVSSGSGRTQSNNNKKNNNGGSTGISHASGSPLTDGNGGNSNGNSRSRSRSRKSSGTTGGLLKKPPLLVNNEAVHASVPDASHTSCNNGTLEVSINNPEPHVVDAVARHLIRNPSNSLQLQGGDITRDLYKWTNDHPSSPSQYQYPSQPALSTSIPSQAPSFSNRKRSMSFSAASIASSSHLNNNSEANGNPLAAIGLAPAPMTHEEIRAPGGFRRSFIIQKRRKHNVDAPIPN-------FFTRNFIEFLTLYGHFAGEDLSEEEEEEEE---TEEEPEEEALETESTQLVSREHGRHPHKSSTVKAVLLLLKSFVGTGVLFLPKAFHNGGWGFSALCLLSCALISYGCFVSLITTKDKVGVDG---------------YGDMG---RILYGPKMKFAILSSIALSQIGFSAAYTVFTATNLQVFSENFFHLK-----------PGSISLATYIFAQVLIFVPLSLTRNIAKLSGTALIADLFILLGLVYVYVYS---IYYIAVNGVASDTMLMFNKADWSLFIGTAIFTFEGIGLLIPIQESMKHPKHFR---PSLSAVMCIVAVIFISCGLLCYAAFGSDVKTVVLLNFPQDTSYTLTVQLLYALAILLSTPLQLFPAIRILENWTFPSN------------------ASGKYNPKVKWLKNYFRCAIVVLTSILAWVGANDLDKFVSLVGSFACIPLIYIYPPLLHYKASILSGTS----RARLLLDLIVIVFGVAVMAYTSWQTIKMWSQ--------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:* .*.* : : .. .* . *: . : . * :: : ... . : : . : : . ::. . :: .:. :: : * * * : . . : :* : *: : : . : : : . : *:. * * :. . .: :: ", "identical_positions": 14, "similar_positions": 63, "identity": "1.74%" }, { "cls_id": "homologset.agr.RGD:1309094", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JZE8-1", "uniprot_id": "A0A0G2JZE8_RAT", "id": "A0A0G2JZE8-1", "name": "Target of EGR1 protein 1", "aln": "MAADSDDGVPSVPTPSDGGVNRTTQSAEEFVVRVPVVDVQSDNFKEIWPSLLLALKTASFVAVDTELSGLGDRKSLLNQCIEERYKAVCHAARTRSVLSLGLACFKQQPDKGDSSYLAQVFNLTLLCMEEYVIEPKSVQFLVQHGFNFNRQYAQGIPYHKGNDKGDESQSQSVRTLFLELIRARRPLVLHNGLIDLVFLYQNFYAHLPENLGTFTADLCEMFPAGIYDTKYAAEFHARFVASYLEYAFRKCERENGKQRAAGSPHVALEFCSYPSSMRGHIDYRCCMSPVSCRHSHTTGICDKFSAYGWCPLGPQCPQSHDIDLIIDTDEAVAEDKRRRRRRKDKRKRALQSQPETQTLEEAEDGPPTKQVCEDSLKTEKIEQKVAE---GDQLGSTQGHKDSLEMACKR----TADVPTSELLVNQASPNPVPGDGLHRAGFDAFMTGYVMAYVGLSKGLQLCSSEPWLPECHNKVYLSGKTVPLTVAKSQFSRPSKAHNQKMKLAWGSS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D2E2-1", "uniprot_id": "TOE1_MOUSE", "id": "Q9D2E2-1", "name": "Target of EGR1 protein 1", "aln": "MAADSDDDVPPVPTPSDGGVNKNTQPAEEFVVRVPVVDVQSDNFKEIWPSLLLALKTASFVAVDTELSGLGDRKSLLNQCIEERYKAVCHAARTRSVLSLGLACFRQQPDKGENSYLAQVFNLTLLCIEEYVIEPKSVQFLVQHGFNFNRQYAQGIPYHKGNDKGDESQSQSVRTLFLELIRARRPLVLHNGLIDLVFLYQNFYAHLPENLGTFTADLCEMFPAGIYDTKYAAEFHARFVASYLEYAFRKCERENGKQRAAGSPHLALEFCSYPSSMSGHIDYRCCMSPGTCRRSRTTGICDKFSAYGWCPLGPQCPQSHDIDLIIDTDEAVAEDKRRRRRRKDKRKRSLQSQPGTQTLAEAEDGPPTKQVCEDSLETEKMEQKVAEGEAGDQPGSREGHTSSLEMAHRRTSAETADVATSELLVNQASTNPVPGDGLHRAGFDAFMTGYVMAYVGLSQGLQLCSSEPWLPECHNKVYLSGKTVPLTVTKSQFSRPSKAHNQKMKLAWGSS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96GM8-1", "uniprot_id": "TOE1_HUMAN", "id": "Q96GM8-1", "name": "Target of EGR1 protein 1", "aln": "MAADSDDGAVSAPAASDGGVSKSTTSGEELVVQVPVVDVQSNNFKEMWPSLLLAIKTANFVAVDTELSGLGDRKSLLNQCIEERYKAVCHAARTRSILSLGLACFKRQPDKGEHSYLAQVFNLTLLCMEEYVIEPKSVQFLIQHGFNFNQQYAQGIPYHKGNDKGDESQSQSVRTLFLELIRARRPLVLHNGLIDLVFLYQNFYAHLPESLGTFTADLCEMFPAGIYDTKYAAEFHARFVASYLEYAFRKCERENGKQRAAGSPHLTLEFCNYPSSMRDHIDYRCCLPPATHR-PHPTSICDNFSAYGWCPLGPQCPQSHDIDLIIDTDEAAAEDKRRRRRRREKRKRALLNLPGTQTSGEAKDGPPKKQVCGDSIKPEETEQEVAADETRNLPHSKQGNKNDLEMGIKAARPEIADRATSEVPGSQASPNPVPGDGLHRAGFDAFMTGYVMAYVEVSQGPQPCSSGPWLPECHNKVYLSGKAVPLTVAKSQFSRSSKAHNQKMKLTWGSS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*******.. ..*:.*****.:.* ..**:**:********:****:*******:***.*************************************:********::*****: *************:*************:*******:***********************************************************.*******************************************************::****.***** .*******:.* : * .:.*.***:****************************.**********::****:* . * *** **:****.**** **::.*: **:** : * :*:...***. : ** .***: .***.************************* :*:* * *** ***************:*****:******.**********:****", "identical_positions": 407, "similar_positions": 67, "identity": "79.65%" }, { "cls_id": "homologset.agr.RGD:1309095", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZZM4-1", "uniprot_id": "A0A8I5ZZM4_RAT", "id": "A0A8I5ZZM4-1", "name": "", "aln": "MSHTEVKLKIPFGNKLLDAVCLVPNKNIA--YGIILTHGASGDMNLPHLMSLASHLASHGFFCLRFTCKGLNIVHRIKAYKAVLNYLKTSGEYKLAGVFLGGRSMGSRAAASVMCHTELDDADDFVRGLICISYPLHHP--KQQHKLRDEDLFRIK-DPVLFVSGSADEMCEK-----------NLLEKVAQKMQAPSKIHWIEKANHSMAVKGRSTNDVFKEINTQILFW--IQEITEMDKKCH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TUU5-1", "uniprot_id": "TEX30_MOUSE", "id": "Q3TUU5-1", "name": "Testis-expressed protein 30", "aln": "MSHTEVKLKIPFGNKLLDAVCLVPNKNIA--YGIILTHGASGDMNLPHLMSLASHLASHGFFCLRFTCKGLNIVHRIKAYKAVLNYLKTSGEYKLAGVFLGGRSMGSRAAASVMCHTEPDDADDFVRGLICISYPLHHP--KQQHKLRDEDLFRIK-DPVLFVSGSADEMCEK-----------NLLEKVAQKMQAPSKIHWIEKANHSMAVKGRSTNDVFKEINTQILFW--IQEITEMDKK--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5JUR7-1", "uniprot_id": "TEX30_HUMAN", "id": "Q5JUR7-1", "name": "Testis-expressed protein 30", "aln": "MSHTEVKLKIPFGNKLLDAVCLVPNKSLT--YGIILTHGASGDMNLPHLMSLASHLASHGFFCLRFTCKGLNIVHRIKAYKSVLNYLKTSGEYKLAGVFLGGRSMGSRAAASVMCHIEPDDGDDFVRGLICISYPLHHP--KQQHKLRDEDLFRLK-EPVLFVSGSADEMCEK-----------NLLEKVAQKMQAPHKIHWIEKANHSMAVKGRSTNDVFKEINTQILFW--IQEITEMDKKCH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QG13-1", "uniprot_id": "A0A8M9QG13_DANRE", "id": "A0A8M9QG13-1", "name": "", "aln": "MEFSEEKVRIPFEQKELDGLFSVPDDVTAGIPAVVLTHGAGGDMRIKQLESLARALACAGVLCLRFTCKAINFVYRVRAYSAVVDYLKAHERFAPSSVFLGGRSMGARTAVAV-CNQMCAVQKDAVQGVLCLSFPLNLPGKPQTYIERSKGLLELSGTPVLFISGTADNMCEQGICGVLKSLKKKILQNIVDTMKSPSAVHWIKDANHGLTVRGRTEESVLEEVNPLIIEWEVYKDWIFLRNLCL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*..:* *::*** :* **.: **:. : .::*****.***.: :* *** **. *.:*******.:*:*:*::**.:*::***: .: :.*********:*:*.:* *: .* *:*::*:*:**: * * : *.:.*:.:. ****:**:**:***: ::*:::.:.*::* :***:.***.::*:**: :.*::*:*. *: * :: : : ", "identical_positions": 94, "similar_positions": 89, "identity": "38.37%" }, { "cls_id": "homologset.agr.RGD:1309096", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GJW6-1", "uniprot_id": "A0A8I6GJW6_RAT", "id": "A0A8I6GJW6-1", "name": "", "aln": "MCREPPSQTTPLSLNLTHIPQSPCSSTEYLAGPWARTGVVAPLCVGAMRILANKTRLPHPRRREAPGSPPLSPRGHCPPAPAKPMHPENKLTNHGKTGNGGAQSQHQNVNQG----PTCNLGSKGVGAGSHGAKANQISPSNSSLKNPQAGVSPFSSLKGKVKRERSVSVDSGEQREAGTPSLDSEAK-EVAPRSKRRCVLERKQPYSGDEWCSGPDSEEDD-KPIGATHNCNVADPAMVAPQLGPGQTAQLPLSENSAPGPQHGPPPGLRPDVPGGGGGG--VPGKPPSQFVYVFTTHLANTAAEAVLQGRAESILAYHQQNVPRAKLDQAP---KVPPTPEPLP-LNTPSAGTPQSQPPPLPPPPP-APGSAP-PALPQEGPPEDTSQDLAPNSVGAASTGG-------GTGGTHPNTPTAATANNPLPPGGDPGS------APGSALLGEATPTGNGQRNLVG-SEGLSKEQLEHRERSLQTLRDIERLLLRSGE--TEPFLKGPPG---------------------GAVEGGPPAQAPSAAQQPPSAPPPG-LKKYEEPLQSMISQTQSLGGPPLEHEVPG-----HPQGGDMGQQMNMMMQ-RLGQDSLTPEQVAWRKLQEEYYEEKRRKEEQIGLHGGRPLQDMVGMGG-----MMGRGPPPPYHSKPGDQ-WPPGMGTQLRGPMDVQDPMQLRPGPPFPGPRFPGNQMQRVPGFGGMQSIP---MEVPMNAMQRPVRPGMAWNEDLPPIGGPSNFAQNAVPYPGGQGEAERFMTPRVREELLRHQLLEKRSMGMQRPLGMAGSGMGQSMEMERMIQTHRQMDPTMFPGQMTGGDGLAGTPMGIEFGGGRGLLSPPMGQSGLREVDPPMGPGNLNMNMNVNMNMNMNLNVQMTPQQQMLMSQKMRGPGDMMGPQGLSPEEMARVRAQNSSGMMAGPQKMLMPS-----QFPNQGQQGFSGGQGPYQAMPQDMGNTPDMFSPDQSSVPMGAVGTARLSHMPLPPASNPPGSVHSAPNRGLGRRPSDLTISINQMGSPGMG---HLKSPTLSQVHSPLVTSPSAN-LKSP----QTPSQMVPLPSANPPGP-----LKSPQVLSSSLSVRSPTGSPSRLKSPSMAVPSPGWVASPKTAMPSPGVSQNKQPPLNINSSSTLGNLEQGALPPAGPRNSSSAPPANPPSSLMNPSLPFTSSPDPTPSQNPLSLMMSQMSKYAMPSSTPLYHNAIKTIATSDDELLPDRPLLPPPPPPQGSGPGISNNQPNQMHMNP-------AAAQSPMGMNLPGQQPLSHEPPPTMLPSPTPLGSNIPLHPNAQGTGGPSQNSMMMAPGGPDSLNTPCGPVPSSSQ-MMSFPPRLQQPHGAMAATGGGG--PGLQQHYPSGMALPPEDLPNQPPGPIPSQQHLMGKGMAGRMGDAYPPGVLPGVASVLNDPELSEVIRPTPTGIPEFDLSRIIPSEKPSSTLQYFPKNENQ------PPKAQPP-------------------------NLHLMNLQNMMAEQAPSRPPNLP-----------GQQGVQRGLSMS-MCHPGQMSLLGRTGVPPQQGMVPHGLHQ-------------------GVMSP---PQGLMTQQNFMLMKQR----GVGGEVYTQPPHMLSPQGSLMAPPPQQN-LMVSHPLRQRSVSLDSQMGYLPTPGGMANLPF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q67FY2-1", "uniprot_id": "BCL9L_MOUSE", "id": "Q67FY2-1", "name": "B-cell CLL/lymphoma 9-like protein", "aln": "-----------------------------------------------MRILANKTRLPHPRRREAPGSPPLSPRGHCPPAPAKPMHPENKLTNHGKTGNGGAQSQHQNVNQG----PTCNLGSKGVGAGSHGAKANQISPSNSSLKNPQAGVSPFSSLKGKVKRERSVSVDSGEQREAGTPSLDSEAK-EVAPRSKRRCVLERKQPYSGDEWCSGPDSEEDD-KPIAAAHNCNVADPAMVTPQLGPGQTAQLPLSESSAPGPQHGPQPGLRPDVPGGGGGG--VPGKPPSQFVYVFTTHLANTAAEAVLQGRAESILAYHQQNVPRAKLDQAP---KVPPTPEPLP-LNTPSAGTPQSQPPPLPPPPP-APGSAP-PALPPEGPPEDTSQDLAPNSVGAASTGG-------GTGGTHPNTPTAATANNPLPPGGDPGS------APGSALLGEATPTGNGQRNLVG-SEGLSKEQLEHRERSLQTLRDIERLLLRSGE--TEPFLKGPPG---------------------GAGEGGPPAQAPSAAQPPPSAPPGG-LKKYEEPLQSMISQTQSLGGPPLEHEVPG-----HPQGGDMGQQMNMMMQ-RLGQDSLTPEQVAWRKLQEEYYEEKRRKEEQIGLHGGRPLQDMVGMGG-----MMGRGPPPPYHSKPGDQ-WPPGMGAQLRGPMDVQDPMQLRPGPPFPGPRFPGNQMQRVPGFGGMQSMP---MEVPMNAMQRPVRPGMAWNEDLPPIGGPSNFAQNAVPYPGGQGEAERFMTPRVREELLRHQLLEKRSMGMQRPLGMAGSGMGQSMEMERMIQAHRQMDPAMFPGQMTGGDGLAGTPMGIEFGGGRGLLSPPMGQSGLREVDPPMGPGNLNMNMNVNMNMNMNLNVQMTPQQQMLMSQKMRGPGDMMGPQGLSPEEMARVRAQNSSGMMGGPQKMLMPS-----QFPNQGQQGFSGGQGPYQAMPQDMGNTPDMFSPDQSSVPMGTVGTARLSHMPLPPASNPPGSVHLASNRGLGRRPSDLTISINQMGSPGMG---HLKSPTLSQVHSPLVTSPSAN-LKSP----QTPSQMVPLPSANPPGP-----LKSPQVLSSSLGVRSPTGSPSRLKSPSMAVPSPGWVASPKTAMPSPGVSQNKQPPLSINSSSTLGNVEQGALPPSAPRNSSSAPPANPSSGLMNPSLPFTSSPDPTPSQNPLSLMMSQMSKYAMPSSTPLYHNAIKTIATSDDELLPDRPLLPPPPPPQGSGPGISNNQPNQMHMNP-------AAAQSPMGMNLPGQQPLSHEPPPTMLPSPTPLGSNIPLHPNAQGTGGSSQNSMMMAPGGPDSLNAPCGPVPSSSQ-MMSFPPRLQQPHGAMAPTGAGG--PGLQQHYPSGMALPPEDLPTQPPGPIPPQQHLMGKGMTGRMGDAYPPGVLPGVASVLNDPELSEVIRPTPTGIPEFDLSRIIPSEKPSSTLQYFPKSENQ------PPKAQPP-------------------------NLHLMNLQNMMAEQTPSRPPNLP-----------GQQGVQRGLSMS-MCHPGQMSLLGRTGVPPQQGMVPHGLHQ-------------------GVMSP---PQGLMTQQNFMLMKQR----GVGGEVYTQPPHMLSPQGSLMGPPPQQN-LMVSHPLRQRSVSLDSQMGYLPTPGSMANLPF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86UU0-1", "uniprot_id": "BCL9L_HUMAN", "id": "Q86UU0-1", "name": "B-cell CLL/lymphoma 9-like protein", "aln": "-----------------------------------------------MRILANKTRLPHPRRREAPGSPPLSPRGHCPPAPAKPMHPENKLTNHGKTGNGGAQSQHQNVNQG----PTCNVGSKGVGAGNHGAKANQISPSNSSLKNPQAGVPPFSSLKGKVKRDRSVSVDSGEQREAGTPSLDSEAK-EVAPRSKRRCVLERKQPYSGDEWCSGPDSEEDD-KPIGATHNCNVADPAMAAPQLGPGQTTQLPLSESSVPGAPHGPPPGLRPDAPGGGGGGGGVPGKPPSQFVYVFTTHLANTAAEAVLQGRADSILAYHQQNVPRAKLDQAP---KVPPTPEPLP-LSTPSAGTPQSQPPPLPPPPPPAPGSAP-PALPPEGPPEDSSQDLAPNSVGAASTGG-------GTGGTHPNTPTATTANNPLPPGGDPSS------APGPALLGEAAAPGNGQRSLVG-SEGLSKEQLEHRERSLQTLRDIERLLLRSGE--TEPFLKGPPG---------------------GAGEGGPPAQAPPPPQQPPTAPPSG-LKKYEEPLQSMISQTQSLGGPPLEHEVPG-----HPPGGDMGQQMNMMIQ-RLGQDSLTPEQVAWRKLQEEYYEEKRRKEEQIGLHGSRPLQDMMGMGG-----MMVRGPPPPYHSKPGDQ-WPPGMGAQLRGPMDVQDPMQLRGGPPFPGPRFPGNQIQRVPGFGGMQSMP---MEVPMNAMQRPVRPGMGWTEDLPPMGGPSNFAQNTMPYPGGQGEAERFMTPRVREELLRHQLLEKRSMGMQRPLGMAGSGMGQSMEMERMMQAHRQMDPAMFPGQMAGGEGLAGTPMGMEFGGGRGLLSPPMGQSGLREVDPPMGPGNLNMNMNVNMNMNMNLNVQMTPQQQMLMSQKMRGPGDLMGPQGLSPEEMARVRAQNSSGVMGGPQKMLMPS-----QFPNQGQQGFSGGQGPYQAMSQDMGNTQDMFSPDQSSMPMSNVGTTRLSHMPLPPASNPPGTVHSAPNRGLGRRPSDLTISINQMGSPGMG---HLKSPTLSQVHSPLVTSPSAN-LKSP----QTPSQMVPLPSANPPGP-----LKSPQVLGSSLSVRSPTGSPSRLKSPSMAVPSPGWVASPKTAMPSPGVSQNKQPPLNMNSSTTLSNMEQGTLPPSGPRSSSSAPPANPPSGLMNPSLPFTSSPDPTPSQNPLSLMMTQMSKYAMPSSTPLYHNAIKTIATSDDELLPDRPLLPPPPPPQGSGPGISNSQPSQMHLNS-------AAAQSPMGMNLPGQQPLSHEPPPAMLPSPTPLGSNIPLHPNAQGTGGPPQNSMMMAPGGPDSLNAPCGPVPSSSQ-MMPFPPRLQQPHGAMAPTGGGGGGPGLQQHYPSGMALPPEDLPNQPPGPMPPQQHLMGKAMAGRMGDAYPPGVLPGVASVLNDPELSEVIRPTPTGIPEFDLSRIIPSEKPSSTLQYFPKSENQ------PPKAQPP-------------------------NLHLMNLQNMMAEQTPSRPPNLP-----------GQQGVQRGLNMS-MCHPGQMSLLGRTGVPPQQGMVPHGLHQ-------------------GVMSP---PQGLMTQQNFMLMKQR----GVGGEVYSQPPHMLSPQGSLMGPPPQQN-LMVSHPLRQRSVSLDSQMGYLPAPGGMANLPF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q67FY3-1", "uniprot_id": "BCL9L_DANRE", "id": "Q67FY3-1", "name": "B-cell CLL/lymphoma 9-like protein", "aln": "------------------------------------------------------------------------------------MHSENKLSNHGKQVTSGAQSQLPNVNQAQQQAPAGIQGSKGSVSGNHGVKANQISPGNPGLKSLNQTGGGGGMMKTKAKRERSVSIDTGDQRESLTPVLEPDAKVEGVMRSKRRCVLERKQPYSGDEWCSGAETEEEDEKPLSATH----REHVMCPSQGHSGSSTTGHVSDPGGPGLGSGHGPGIRTDLHS----------RPPQQVVYVFTTSLANSAAEAVMHGHTDSILLYHQQNVPRTKLDQSTGVGKVSNLAEHISSSHSPPIGTPKSQSGTPRPASVGGVGHLPGTSTPSSTGHPDSEPAQTHRGGGTSSNNGRSAVHTLGLGNSGPQSVGVSGTEGVDRPGAIPHHGAGVSPSTSPSVLSALRQSELGQRVGPGNTDGLSKEQLEHRERSLQTLRDIERLLLRSGTGVAQEDPRGPNGNPNGTNVNNNNSNDGGRGLEDGEIGGGIPGNCHINNAGMPGMPPVGGMKKYEEPLQSIISQTQNLGGPGLDDSLMGPHHGMPPHSHHLSSPSGLDMGPLLGPEGVTPEQLAWRKLQEEYYQEKRRQHDMNPHQHPQHFRIMPEMGMPGGPPMLMRGPPPPYHSKPGDQQWGP--GPMVGGGMGGNARMMDMNQEGPRGPRFLG-QMRGPSGGGGYPESPGGVLGVEGLGPQRPPRPGMGWLEEIPPNMGGGGPFHGCCP-PGGPGGPPQHFQGDLDRPMTREEIY--RRIHRLDLQQMSRQQQQAGLGGPRMMDNP--GGPGFPNPGMAGGPPSRGDPM--DFPVSRTIMGSPIG--GVGGDGGPTMRDIVDSPLGGNLNMNMGMNIN---QQQQLLAQKLRGGPGVLG-EMLNAEDISRIRASQNG--RGGANKAMIPGPEGPLQFPNQSS--FPGGQVDGPYLQQPG---PDMYGPDQPGPPHLSS-TSRLSHIPMNTGSR-------VTDLG-ARHPPDLPISVNPMGSPAIPPSHQLKSPSLSQEPSPLMPSPSAAGLKSPSQLPQSGPTHPPLPAASGAGTPSSTSIKSPQVMGPSLGLRSPSGSPGHLKSPSMPVASPGWTASPKAAMPSPGGP----PSVKVTGNGGSSSTDTGMSLP--PRSSNSTPISQP-SNSINPSMPFTSSPDAPPSQNPLSLIMSQMSKYAMPSSTPLYHDAIKTIATSDDEMLPDRPLQPGTNMSVG---GMGNHQSAQMLLSSQGAMGPHSGPQSPMGMVLQGGPPLSHDHPGPMLPSPNPMG--IPGMPSEIMGGG----------GGPPDGIGPCNVSPMHTQNQMGGFPRIQGP--LHSPIGGMG------QQFPP---RPDDVLP-------PQQMHLLSKGMSHQRPPHQPDSFPP--MPMGDGPDLSEVIRPTHRGIPEFDLSRIIPADKPSSTLQYFPKSETMSQPQQNPHQGQPPPQVSSAQLLKQLSSSGPPHSNIPSSNPHIANLQNMMAEQQLPLHPSHCGMRPGMGMPQIGSRGMGSGGGMGPMCHPGHM--MGRTGMSPQQQLQQQHHHQQQQAMMANNLLQHPSHPPRGMLSPQQHPHNLIAQQNLMMMQAKQRGMALPGEHFGQQGALMSPQGPMMGPPHSQTGMMGPQSLRQRSMSLDSPLGYG--PGSMANMPF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **.****:**** ..***** ****. *: **** :*.**.*******.*..**. : . :* *.**:****:*:*:***: ** *:.:** * . **********************.::**:* **:.*:* : .* ..* .*.:: :*: . ** * **:*.* . :**.*.****** ***:*****::*:::*** ********:****:. **. .* :. :*. ***:**. . *.. . * * .: * . *:. : .. *::*..* * *.: *:: .: ::. **. * :...::*. . *** * ::**************************** :: :** * * ** *.:. * ** * :*********:*****.**** *:..: * * . .:.. .: : ** :.:****:**********:****:.: : : :: * ** *: ************** * * *. : * *. : * **** * *:: .* ** . * : * . *** ****.* *::** * .. :. * *** * . :.: : . : *.:: * : *: . .: **:: .* : *:** * ** :* .* ::..*:* *: . * . :: :. *:****.:*:: *** *::**:** .::* : *..*:::*:**.:.. .*.:* ::*. *****.. *.*** : * **:.***.. * *:****:*: ..*. ..: * .*:*.**.**:* ****.: :****:*** ***:.**** **** *: . ***:*. .*. :*****:..**.:***:***.:******.*.****.****:****** . *.:.:... .. : * * **.*.*:* ::* *. :***:*******..********:*:***************:***********:****** * . . * *:.* *. ** :.. :..****** * * ****: * .*****.*:* ** *. ** *** . **. * :* * **:* * :. *. * *::*. * : ** * * **:.*.*: : * .. * .: :.*:******** ************::***********.*. * :.*** * *: ********* . *. *.:*: * .*. *****:* :****:.*** : : ** *::** *:.*::***:*:*: : .: ** : * ::****.:*.** .*. :* .:.*****:**** :** **.***:**", "identical_positions": 651, "similar_positions": 375, "identity": "38.16%" }, { "cls_id": "homologset.agr.RGD:1309097", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4ADA1-1", "uniprot_id": "D4ADA1_RAT", "id": "D4ADA1-1", "name": "", "aln": "MVHERWKTVGGASQLEDRPRDKPQRAGCSYILCTVLLSLAVLLAVAVTGAVLFLNHAHAPGTAP-PPIVSTGAAGANSALVTVERADSSHLSLLIDPRCPDLTDSFARLEGIQASILRTLSEHQAQPRLDG--APELLDALADQLPRLLARASELQAECAGLRKGHSLLGQGLSTLQSEQGRLIQLLSESQGHMAHLVNSVSDVLEALQRERGLGRPRVKADLQRAPSRGARPRGCANGSRPRDCLDVLLSGQQDDGVYSVFPTHYPAGFQVYCDMRTDGGGWTVFQRREDGSVNFFRGWEAYREGFGKLTGEHWLGLKRIHALTTQAAYELHVDLEDFDNGTAYAHYGSFGVGLFSVDPEEDGYPLT-VADYSGTAGDSLLKHSGMRFTTKDRDSDHSENNCAAFYRGAWWYRNCHTSNLNGQYLRGPHASYAD--GVEWSSWTGWQYSLKFSEMKIRPLREDR---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2AV25-1", "uniprot_id": "FBCD1_MOUSE", "id": "A2AV25-1", "name": "Fibrinogen C domain-containing protein 1", "aln": "MVHERWKTVGSASQLEDRPRDKPQRASCSYVLCTVLLSLAVLLAVAVTGVVLFLNHTHTPGTAP-PPIVSTGTAGANSALVTVERADSSHLSLLIDPRCPDLTDSFARLEGIQASILRALSEHQAQPRLDG--APELLDALADQLPRLLTRASELQAECAGLRKGHSLLGQGLSTLQSEQGRLIQLLSESQGHMAHLVNSVSDVLEALQRERGLGRPRVKADLQRAPSRGARPRGCANGSRPRDCLDVLLSGQQDDGVYSIFPTHYPAGFQVYCDMRTDGGGWTVFQRREDGSVNFFRGWEAYREGFGKLTGEHWLGLKRIHALTTQAAYELHVDLEDFDNGTAYAHYGSFGVGLFSVDPEEDGYPLT-VADYSGTAGDSLLKHSGMRFTTKDRDSDHSENNCAAFYRGAWWYRNCHTSNLNGQYLRGAHASYAD--GVEWSSWTGWQYSLKFSEMKIRPVREDR---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N539-1", "uniprot_id": "FBCD1_HUMAN", "id": "Q8N539-1", "name": "Fibrinogen C domain-containing protein 1", "aln": "MVNDRWKTMGGAAQLEDRPRDKPQRPSCGYVLCTVLLALAVLLAVAVTGAVLFLNHAHAPGTAP-PPVVSTGAASANSALVTVERADSSHLSILIDPRCPDLTDSFARLESAQASVLQALTEHQAQPRLVGDQEQELLDTLADQLPRLLARASELQTECMGLRKGHGTLGQGLSALQSEQGRLIQLLSESQGHMAHLVNSVSDILDALQRDRGLGRPRNKADLQRAPARGTRPRGCATGSRPRDCLDVLLSGQQDDGVYSVFPTHYPAGFQVYCDMRTDGGGWTVFQRREDGSVNFFRGWDAYRDGFGRLTGEHWLGLKRIHALTTQAAYELHVDLEDFENGTAYARYGSFGVGLFSVDPEEDGYPLT-VADYSGTAGDSLLKHSGMRFTTKDRDSDHSENNCAAFYRGAWWYRNCHTSNLNGQYLRGAHASYAD--GVEWSSWTGWQYSLKFSEMKIRPVREDR---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A5PMA3-1", "uniprot_id": "A5PMA3_DANRE", "id": "A5PMA3-1", "name": "", "aln": "MLNDRWGIMNSSPELEDGQRGKNQRMSCSYLLCTILLFVAVLLAVTVTGTILLMNHYQAPPMSDGPPHISTNQDEAN-ALVTVERGDGSRINIFIDPNCPDYNSNFLRLEGVQTSLLHSLTDHDTDLKSVKGQDRALLVNLAEEVAKLSAHAGQLKMDYESLRRGQSNLGQDLNTLQTEQSRLIQLLSESQINMVKVVNSVSDALNAMQKETGGLKARVKADLQRAPVRGVRLKGCANGSRPRDCSDIYASGQREDGIYSVFPTHYPAGFQVYCDMSTDGGGWT---RREDGSVNFFREWDSYREGFGKITGEYWLGLKQIHALSIQGNYELRIDLEDFENSTAFAQYGVFGVGLFSVDPEDDGYPLT-IADYTGTAGDSLLKHNGMKFTTKDRDNDHSENNCASFYHGAWWYRNCHTSNLNGQYLRGQHTSYAD--GIEWSSWTGWQYSLKFTEMKIRPTRDERETK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VME7-1", "uniprot_id": "Q9VME7_DROME", "id": "Q9VME7-1", "name": "Fibrinogen C-terminal domain-containing protein", "aln": "-------------------------------------MRSVWIYVAFLG------------------------------------------------------LSFYSTEAMDSESFQNDTAIRNKP-----------------------------------------------ELKSLYKLVLALLEENQSNASTEN-----------------IQKSSSDLNTTGLSGRYPSQCPTYPPAHGIYTVQVLGLKP--------------FQVSCDAEIAGTGWTVMARRTSNKLNFFRSWAEYKNGFGQLDGDFFIGLDKLHAITKSQPHELYIHLEDFEGQTRYAHY-----DEIFIESENKFYAMTKLGEFTGDAGDSMIHNRNQNFSTFDRDNDGWHKNCAEEYVGAWWHLNCTYSNLFGIYVKGDEGQYFQWKGIVWHSWRTESYSYKVMQMMVRPKCHCSG--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* : *:. * .* *. ::. :: : . *:: :: **.*.* : : .:**: : * *.. . .:. : * : *** ** * *** ** ...:**** * *::***:: *:.::**.::**:: . :** :.****:. * :*:* . : ::.*:. *.:* :.:::* ****:::: . .*:* ***.* .:*** * ****: ** *** * *::* . .* : *: * ** .** *. :* :** . ", "identical_positions": 90, "similar_positions": 94, "identity": "19.23%" }, { "cls_id": "homologset.agr.RGD:1309098", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZDS3-1", "uniprot_id": "D3ZDS3_RAT", "id": "D3ZDS3-1", "name": "Tyrosine-protein kinase", "aln": "---------------------------------MVSLDKAHLGP-------------------------KYVGLWDFKARTDEELSFQAGDLLHVT-RKEEQWWWATLLDAEGKALAEGYVPHNYLAEKETVESEPWFFGCISRSEAMHRLQSEDYPKGTFLIRVSQKPGADYVLSVWD---AEAVRHYRIWRNSAGRLHLNEVVSFSSLSELVNYHKTHNLSPGLQLSMACWKLK-TEP--LPH--WDDWERPREEFTLCKKLGSGYFGEVFEGLWKGLVRVAVKVISRDNLLHQHTFQAEIQAMKKLRHKHILSLYAVATAGDPVYIITELMPKGSLLQLLRDSDEK--DLPILELVDFASQVAEGMCYLESQNYIHRDLAARNVLVTENNLCKVGDFGLARLVKEDIYLSRD-HNVPYKWTAPEALSRGHYSIKSDVWSFGVLLHEIFSRGQMPYPGMSNHETFLRVDAGYRMPCPLECPPNIHKLMLSCWSRDPKQRPCFKDLCEKLSGITR---YENLV-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q64434-1", "uniprot_id": "PTK6_MOUSE", "id": "Q64434-1", "name": "Protein-tyrosine kinase 6", "aln": "---------------------------------MVSWDKAHLGP-------------------------KYVGLWDFKARTDEELSFQAGDLLHVT-KKEELWWWATLLDAEGKALAEGYVPHNYLAEKETVESEPWFFGCISRSEAMHRLQAEDNSKGAFLIRVSQKPGADYVLSVRD---AQAVRHYRIWKNNEGRLHLNEAVSFSNLSELVDYHKTQSLSHGLQLSMPCWKHK-TEP--LPH--WDDWERPREEFTLCKKLGAGYFGEVFEALWKGQVHVAVKVISRDNLLHQHTFQAEIQAMKKLRHKHILSLYAVATAGDPVYIITELMPKGNLLQLLRDSDEK--ALPILELVDFASQVAEGMCYLESQNYIHRDLAARNVLVTENNLCKVGDFGLARLVKEDIYLSHE-HNVPYKWTAPEALSRGHYSIKSDVWSFGVLLHEIFSRGQMPYPGMSNHETFLRVDAGYRMPCPLECPPNIHKLMLSCWSRDPKQRPCFKDLCEKLTGITR---YENLV-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13882-1", "uniprot_id": "PTK6_HUMAN", "id": "Q13882-1", "name": "Protein-tyrosine kinase 6", "aln": "---------------------------------MVSRDQAHLGP-------------------------KYVGLWDFKSRTDEELSFRAGDVFHVA-RKEEQWWWATLLDEAGGAVAQGYVPHNYLAERETVESEPWFFGCISRSEAVRRLQAEGNATGAFLIRVSEKPSADYVLSVRD---TQAVRHYKIWRRAGGRLHLNEAVSFLSLPELVNYHRAQSLSHGLRLAAPCRKHE-PEP--LPH--WDDWERPREEFTLCRKLGSGYFGEVFEGLWKDRVQVAIKVISRDNLLHQQMLQSEIQAMKKLRHKHILALYAVVSVGDPVYIITELMAKGSLLELLRDSDEK--VLPVSELLDIAWQVAEGMCYLESQNYIHRDLAARNILVGENTLCKVGDFGLARLIKEDVYLSHD-HNIPYKWTAPEALSRGHYSTKSDVWSFGILLHEMFSRGQVPYPGMSNHEAFLRVDAGYRMPCPLECPPSVHKLMLTCWCRDPEQRPCFKALRERLSSFTS---YENPT-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7TED1-1", "uniprot_id": "A0A8N7TED1_DANRE", "id": "A0A8N7TED1-1", "name": "Tyrosine-protein kinase", "aln": "-------------MSQEEVCCSCPGLRAFCQGLFTSPDKTEAEKPTNTAKQTVNVPNPSRASACEPGSELYKALWSYKARGADELSFQEGEQFRIC-ERQGEWWTALKLGRDGAVTGRGFVPNHFLARRQTVKEQPWYFGTLNRFETEILLLAPENDVGAFLVRHSEKDNIGYVLSVLSGDRSREVKHIKIHQNQNESFYLDKSQTFQSLEKLVDYYWKYSLDGDSFLKQPCRRPE-PKPKDLSHSTVNDWELPKEEFTLEEELGKGFFADVYRGKWKGMVNVAIKILKNDSINHR-EFMLETQILKKLRHKHLIALFAVCTSSSPFYIITELMEKGDLLSLLKGKEGQ--DLNAQMLTEMASQVADGMAYLEEQNSIHRDLAARNVLVGANYICKVADLGLARIVKESVYSSED-AQIPYKWSAPEAISHGRFSNKSDVWSFGVLLYEMFTYGGVPYPAFSNIEVYNMITSGYRMPAPPNCPSHIYDIMLMCWRYSAEERPDFSELLRLLEDYCAPCTDQNTESCSGT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V9J3-1", "uniprot_id": "SRC42_DROME", "id": "Q9V9J3-1", "name": "Tyrosine-protein kinase Src42A", "aln": "MGNCLTTQKGEPDKPADRIKLDDPPTIGVGVGVPQIPMPSHAGQPPEQIRPVPQIPESETAGAN---AKIFVALYDYDARTDEDLSFRKGEHLEILNDTQGDWWLARSK----KTRSEGYIPSNYVAKLKSIEAEPWYFRKIKRIEAEKKLLLPENEHGAFLIRDSESRHNDYSLSVRD---GDTVKHYRIRQLDEGGFFIARRTTFRTLQELVEHYSKDSDGLCVNLCKPCVQIEKPVTEGLSHRTRDQWEIDRTSLKFVRKLGSGQFGDVWEGLWNNTTPVAIKTLKSGTMDPK-DFLAEAQIMKKLRHTKLIQLYAVCTVEEPIYIITELMKHGSLLEYLQAIAGKGRSLKMQTLIDMAAQIAAGMAYLESQNYIHRDLAARNVLVGDGNIVKIADFGLARLIKEDEYEARVGARFPIKWTAPEAANYSKFSIKSDVWSFGILLTELVTYGRIPYPGMTNAEVLTQVEHGYRMPQPPNCEPRLYEIMLECWHKDPMRRPTFETLQWKLEDFYTSDQSDYKEAQAY-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. : .*:.:.:* ::***: *: :.: : ** * . ..*::* :::*. :::: :**:* :.* *: * *:**:* *:. .* *** . *:* :* : :.: . :* .* :**::: . . * .* : : . . *.* ::** : .:.: .:** * *.:*:.. *:. . **:* :. ..: : : * * :*****.::: *:** : .*.******* :*.**. *: : * * ::* *:* **.***.** *********:** . : *:.*:****::**. * :. ..* **:**** . .::* ********:** *:.: * :***.::* *. : ***** * :* . ::.:** ** .. .** *. * * . : ", "identical_positions": 144, "similar_positions": 146, "identity": "27.22%" }, { "cls_id": "homologset.agr.RGD:1309099", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "O96015-1", "uniprot_id": "DNAL4_HUMAN", "id": "O96015-1", "name": "Dynein axonemal light chain 4", "aln": "MGETEGKKDEADYKRLQTFPLVRHSDMPEEMRVETMELCVTACEKFSNNNESAAKMIKETMDKKFGSSWHVVIGEGFGFEITHEVKNLLYLYFGGTLAVCVWKCS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DCM4-1", "uniprot_id": "DNAL4_MOUSE", "id": "Q9DCM4-1", "name": "Dynein axonemal light chain 4", "aln": "MGETEGKKEEADYKRLQTFPLVRHSDMPEEMRVETMELCVTACEKFSNNNESAAKMIKETMDKKFGSSWHVVIGEGFGFEITHEVKNLLYLYFGGTLAVCVWKCS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6A5P7-1", "uniprot_id": "A0A8I6A5P7_RAT", "id": "A0A8I6A5P7-1", "name": "Dynein light chain", "aln": "MGETEGKKEEADYKRLQTFPLVKHSDMPEEMRMETMELCVTACEKFSNNNESAAKMIKETMDKKFGSCWHVVIGEGFGFEITHEVKNLLYLFFGGTLAVCVWKCS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A1Z8T9-1", "uniprot_id": "A1Z8T9_DROME", "id": "A1Z8T9-1", "name": "Dynein light chain", "aln": "MADEEAGK-EGEKKIVHVYPLVKHTDMNEEMRIEAIELSITACEKYSSNYEHAAKIIKENMDKKFGIYWHVVVGEGFGFEVSYETENILYLFFAGNLAIVLWKCS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.: *. * *.: * ::.:***:*:** ****:*::**.:*****:*.* * ***:***.****** ****:*******:::*.:*:***:*.*.**: :****", "identical_positions": 62, "similar_positions": 32, "identity": "59.05%" }, { "cls_id": "homologset.agr.RGD:1309100", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABZ3NNP9-1", "uniprot_id": "A0ABZ3NNP9_RAT", "id": "A0ABZ3NNP9-1", "name": "Leucine-zipper-like transcriptional regulator 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAG---SGGPTGPGALTGGVSSKVAPSVDFDHSCSDSVEYLTLNFGPFETVHRWRRLPPCDEFVGARRSKHTVVAYKDAIYVFGGDNGKTMLNDLLRFDVKDCSWCRAFTTGTPPAPRYHHSAVVYGSSMFVFGGYTGDIYSNSNLKNKNDLFEYKFATGQWTEWKIEGRLPVARSAHGATVYSDKLWIFAGYDGNARLNDMWTIGLQDRELTCWEEVAQSGEIPPSCCNFPVAVCRDKMFVFSGQSGAKITNNLFQFEFKDKTWTRIPTEHLLRGSP-PPPQRRYGHTMVAFDRHLYVFGGAADNTLPNELHCYDVDFQTWEVVQPSSDSEVGGAEVPERASSSEEASTLTSEERSSFKKSRDVFGLDFGTTSTKQPVHLASELPSGRLFHAAAVISDAMYIFGGTVDNNIRSGEMYRFQFSCYPKCTLHEDYGRLWEGRQFCDVEFVLGEKEECVQGHVAIVTARSRWLRRKIVQAREWLAQKLEEDGALAPKEAPG----STVGRAR--PPLLRVAIREAEARPFEVLMQFLYTDKIKYPRKGHVEDVLLIMDVYKLALSFQLCRLEQLCRQYIEASVDLQNVLAVCECAARLQLGQLKEHCLNFIVKESHFNQVIMMKEFERLSSPLIVEIVRRKQQPPPRTP-SDQPVDIGTSLIQDMKAYLEGAGSEFCDITLLLDGHPRPAHKAILAARSSYFEAMFRSFMPEDGQVNISIGEMVPSRQAFESMLRYIYYGEVNMPPEDSLYLFAAPYYYGFYNNRLQAYCKQNLEMNVTVQNVLQILEAADKTQALDMKRHCLHIIVHQFTKVRLWLSPAGLGTSWPLPTVLRQPRPEQAGPQEDFSAHPGPPGILVSSSFGHLCRSLSCPHCGC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQ33-1", "uniprot_id": "LZTR1_MOUSE", "id": "Q9CQ33-1", "name": "Leucine-zipper-like transcriptional regulator 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAG---SGGPIGSGALTGGVRSKVAPSVDFDHSCSDSVEYLTLNFGPFETVHRWRRLPPCDEFVGARRSKHTVVAYKDAIYVFGGDNGKTMLNDLLRFDVKDCSWCRAFTTGTPPAPRYHHSAVVYGSSMFVFGGYTGDIYSNSNLKNKNDLFEYKFATGQWTEWKIEGRLPVARSAHGATVYSDKLWIFAGYDGNARLNDMWTIGLQDRELTCWEEVAQSGEIPPSCCNFPVAVCRDKMFVFSGQSGAKITNNLFQFEFKDKTWTRIPTEHLLRGSP-PPPQRRYGHTMVAFDRHLYVFGGAADNTLPNELHCYDVDFQTWEVVQPSSDSEVGGAEMPERASSSEDASTLTSEERSSFKKSRDVFGLDFGTTSAKQPVHLASELPSGRLFHAAAVISDAMYIFGGTVDNNIRSGEMYRFQFSCYPKCTLHEDYGRLWEGRQFCDVEFVLGEKEECVQGHVAIVTARSRWLRRKIVQAQEWLAQKLEEDGALAPKEAPG----PAVGRAR--PPLLRVAIREAEARPFEVLMQFLYTDKIKYPRKGHVEDVLLIMDVYKLALSFQLCRLEQLCRQYIEASVDLQNVLVVCESAARLQLGQLKEHCLNFIVKESHFNQVIMMKEFERLSSPLIVEIVRRKQQPPPRTP-SDQPVDIGTSLIQDMKAYLEGAGSEFCDITLLLDGQPRPAHKAILAARSSYFEAMFRSFMPEDGQVNISIGEMVPSRQAFESMLRYIYYGEVNMPPEDSLYLFAAPYYYGFYNNRLQAYCKQNLEMNVTVQNVLQILEAADKTQALDMKRHCLHIIVHQFTKVS------------KLPTLRLLSQQLLLDIIDSLASHIS----------DKQCAELGADI---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N653-1", "uniprot_id": "LZTR1_HUMAN", "id": "Q8N653-1", "name": "Leucine-zipper-like transcriptional regulator 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAGPGSTGGQIGAAALAGGARSKVAPSVDFDHSCSDSVEYLTLNFGPFETVHRWRRLPPCDEFVGARRSKHTVVAYKDAIYVFGGDNGKTMLNDLLRFDVKDCSWCRAFTTGTPPAPRYHHSAVVYGSSMFVFGGYTGDIYSNSNLKNKNDLFEYKFATGQWTEWKIEGRLPVARSAHGATVYSDKLWIFAGYDGNARLNDMWTIGLQDRELTCWEEVAQSGEIPPSCCNFPVAVCRDKMFVFSGQSGAKITNNLFQFEFKDKTWTRIPTEHLLRGSP-PPPQRRYGHTMVAFDRHLYVFGGAADNTLPNELHCYDVDFQTWEVVQPSSDSEVGGAEVPERACASEEVPTLTYEERVGFKKSRDVFGLDFGTTSAKQPTQPASELPSGRLFHAAAVISDAMYIFGGTVDNNIRSGEMYRFQFSCYPKCTLHEDYGRLWESRQFCDVEFVLGEKEECVQGHVAIVTARSRWLRRKITQARERLAQKLEQEAAPVPREAPG----VAAGGAR--PPLLHVAIREAEARPFEVLMQFLYTDKIKYPRKGHVEDVLLIMDVYKLALSFQLCRLEQLCRQYIEASVDLQNVLVVCESAARLQLSQLKEHCLNFVVKESHFNQVIMMKEFERLSSPLIVEIVRRKQQPPPRTP-LDQPVDIGTSLIQDMKAYLEGAGAEFCDITLLLDGHPRPAHKAILAARSSYFEAMFRSFMPEDGQVNISIGEMVPSRQAFESMLRYIYYGEVNMPPEDSLYLFAAPYYYGFYNNRLQAYCKQNLEMNVTVQNVLQILEAADKTQALDMKRHCLHIIVHQFTKVS------------KLPTLRSLSQQLLLDIIDSLASHIS----------DKQCAELGADI---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NBN9-1", "uniprot_id": "A0A8M1NBN9_DANRE", "id": "A0A8M1NBN9-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSWFPGAMS--CKSKVAPSVDFDHSCSDSVEYLTLNFGPFETVHRWRRLPPCDEFVGARRSKHTVVAYRDAIYVFGGDNGKNMLNDLLRFDVKDCSWCRAFTTGTPPAPRYHHSAVVYGSSMFVFGGYTGDIYSNSNLKNKNDLFEYKFATGQWTEWKVEGRL-VARSAHGATVYNDKLWIFAGYDGNARLNDMWTIGLQDREQAYWEEIEQSGEIPPSCCNFPVAVCRDKMFVFSGQSGAKITNNLFQFEFKGHIWTRIPTEHLLRGSP-PPPQRRYGHTMVAFDRHLYVFGGAADNTLPNELHCYDVDSQTWEVIQPSIDS----------------------------------------------------EMPSGRLFHAAAVIHDAMYIFGGTVDNNVRSGEMYRFQFSCYPKCTLHEDYGKLWENRQFCDVEFILGEREEKVLGHIAIVTARCKWLRKKILQARDRQKQKSKLECNEESDESGSGSQKDCSGRSSRGPPLLEVSIREADAQPFEVLMQFLYTDKIQYPRRGHVQDVLLIMDVYKLALSFKLSRLEQLCVQYIEASVDLQNVLSVCENADKLQLDQLKEHCLNFVVKESHFNQVIMTKEFEHLSTPLIVEIVRRKQQPPPRVY-SDQPVDIGTSLVQDMKAYLEGAGHEFCDIILLLDGHPRPAHKAILAARSSYFEAMFRSFMPEDGQVNISIGEMVPSTQAFESMLRYIYYGDVDMPPEDSLYLFAAPYYYGFSNNRLQAYCKQNLEMNVTVENVLQILEAADKTQALDMKKHCLHIIVHQFTKVS------------KLPNLRSLSQPLLLDIIDSLASHIS----------DKQCTEMSSDI---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V410-1", "uniprot_id": "LZTR1_DROME", "id": "Q9V410-1", "name": "Leucine-zipper-like transcriptional regulator 1 homolog", "aln": "MLKSISGGVGVASTERGGGGGGCGGGGAGGSASGSRSTSGSGRASCGLGSSSISSGLSAVCGFVTGASGGGGFERDRDRDRGLANISGGSTPAGILYCPACMAAANQQSPSQNSSPHHESFFLRSSFKSSKRNKARKSASTAGCLDAQHIRANLRMSMSSSMRSSRGNGGGGAASSSHPPGSSCSSGPGGSGCSMAYDAASNASSGSGSGSGKATSPGSYSCNALNVDFTSYTATHQWTRMLECAEFVGAKRSKHTVVAYKDAMFVFGGDNGKNMLNDLIRFGVKDKSWGRACATGTPPAPRYHHSAVVAGSSMFIFGGYTGDIHSNSNLTNKNDLFEYKFQSAMWVEWKFSGRQPVPRSAHGAAVYDNKMWIYAGYDGNARLNDMWTLNLTGENQ--WEEVDQLGDRPPTCCNFPVAVARDAMYVFSGQSGLQITNSLFEFHFKTRTWRRISNEPVLRGATSAPPSRRYGHTMVHHDRFLYVFGGSADSTLPNDLHCYDLDSQVWSVIQPEQNS----------------------------------------------------DVPSGRVFHASAVICDAMYIFGGTVDNSVRRGDTYRFQFSSYPKCTLRDDFGKFFQDKQFCDIQFIVGAEEIRILAHIAFVAARSKYLRNKILAAREARQQQMEKVYGVGQVDALALN--AGAGGDR--GPMLEVRLANASPEAFEIILNYIYTDRIDLKDTYSKNIIILITDIYQLAGLFTMPRLAHGCIQYLDYKINKLNVLEALYNADKSNIKIIKDHCMQFIIKEENFTDVVMSSEFSDLDKPLLVEIIRKRLYPSKLVIDTSYEGNIGTTLEIDLCAFLESTGKDFCDISLVLEDHVIPAHKSVLSSRCTYFQGMFRSFMPPDNTVNIQIGEISPSLEAFHSLLRYIYYGETKMPPQDALYLFQAPCFYGLANNRLHAFCKYSLEHNITFENVLQTLEASDITKIYDIKEYALKLIVKDFAKVA------------RLPKIAGLSRELLLEIIRAVADSHG---------EFLTRININTDI---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : .. : * . . * * : *.::* .: :.*:* *: * *****:*********:**::********.*****:**.*** ** ** :*************** *****:********:*****.********** :. *.***..** *.******:**.:*:**:**************:.* ..: ***: * *: **:********.** *:******* :***.**:*.** : * **..* :***:. .**.******** .**.******:**.****:*****:* *.*.*:**. :* ::****:***:*** ************.:* *: ******.******::*:*::::.:****::*::* .* : .*:*:*:**.::**.** *:: *: : :: . * *:*.* : :*....**::::::***:*. : ::** *:*:** * : ** : * **:: .:: *** . * : :: :*:**::*::**.:*.:*:* .**. *..**:***:*:: *. . . :***:* *: *:**.:* :**** *:*:.: ****::*::*.:**:.******* *. ***.***: ** :**.*:*******:..***:*:**** ** :**: ****:*:** .** *:*.:**** ***:* *: *:*.:.*::**::*:** **.: .: .: . .:. ", "identical_positions": 393, "similar_positions": 222, "identity": "37.18%" }, { "cls_id": "homologset.agr.RGD:1309101", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZZ61-1", "uniprot_id": "D3ZZ61_RAT", "id": "D3ZZ61-1", "name": "Centrosomal protein of 68 kDa", "aln": "-MSLGEDEAETKVSVNTEVPSCGRWDSGN---LLSPGQEPE---HLEVQGG---PQWRAE----------ADPGCISGVFLSQTYTASKEPVAGRSEPPLSGPLPSASVGTGELLHPMGSQMEENKPPASRDLLPAIKVLGTITVCSGREADSEDFQPAVAPSQVLGLGQQPHISGLPLLSQWKPTVSPG-APQLSSRSISVSSVGSSLQDHLDKAEPQSGSFAHISS-QELTVPQAAHSVVGAGSPFQWSTQPVASGGDATGLGKRHLSFQAEYWACVLPNSLPPSPNRHSPLWNPNKEYEDLLDYTYPLRP---GPQLPKQLESHVLADPVMQDSGVDLDSFSVSPASTLKSPTNVSHNCSSAEVPTLPLSGAREPCLERWPLGVSQKQGGASLASWNQLASTPRTPGTEGASWENREAALRGTTEDYLPRGKNASAGSPQLKTKEKGPPFPRGEREKTGRQSAGCPACVKPEWPSEEEIGSDEEYLALPSRLTQVSSLVSYSGARPTYVNPPTGAAEGHRSLQVSDSDEPASPTLDSSQRQHPSGTTFQG---PVGQSPCFGHS-VQPQDSRGKSRLMSSQTLGVSAKQLKTHPSSKAVSDKWLLSEPVAGEKLPRRIEEQEKASLLQCVQTFCCQLEELICWLYNVTDVADLSAPPRASLTGLKSSLQLYRQFKKDIDEHQSLTESVLEKGEILLQCLLDNTPVLKDVLVRIAEQSGELESRADHLYDSILASLDKLAGCTLIPDNKPRAAAEHLHEGP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C0D9-1", "uniprot_id": "CEP68_MOUSE", "id": "Q8C0D9-1", "name": "Centrosomal protein of 68 kDa", "aln": "-MALSEDEAEAEVSVNTKVPSCGRWNSGK---LLPSGLEPDQPLHLGVEGG---PLWRAE----------ADPGCISGVFLSRVHTASKEPVADRSKPPLRGPLPSASVGTGEVLHSMGSQMEEDRLPASQDLLPALQVFGTITVCSGQEADSEDFQATLDPSQVLGLSQQPHTSGLPLPPQWKSTVSPG-APQLSSRSISASSVGSSLQDHQEKAGPQRASFANVSS-PELTVPQAAHSVVGAGPPLQGSAQPLTSGSDATGLGKRHLSFQAEYWACALPNSLPPSPNRHSALWDPNKEYEDLLDYTYPLRP---GPQLPKQPESHVLTEPVLQDSGVDLDSLSVSPASTLKSPTNVSHNCSSAEVPTLPFSGARESCLKRWPLGIFQKQGGTSLSSWNQLASTPRAPGTEDASWENREAALRGTAEDCLPIGEDLRMGSPQLKTKEKEPPFP---RQKRGRQHVSCPACVTPGWPSEEEVGSDEEYLALPTRLTQVSSLVSYSGARPSFVNLHTGAAEEHSSLQVSDSDKPASPTLDSSHRKHPSGTSFQG---PVGQNPCFRHS-IQPQDSRGKSSLMSNQTLGVSSKPLKTQPASKAMTDRRLFSELVAGETLPRTTDEQEKASLVQCVQTFCCRLEELICWLYNVTDVADLSAPPRTSLTGLKSSLQLYRQFKKDVDEHQSLTESVLEKGEILLQCLLDNTPVLKDVLERIAKQSGELESRADHLYDSILASLDMLAGCTLIPDNRP-TAAEHPHEGL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q76N32-1", "uniprot_id": "CEP68_HUMAN", "id": "Q76N32-1", "name": "Centrosomal protein of 68 kDa", "aln": "-MALGEEKAEAEASEDTKAQSYGRGSCRERELDIPGPMSGEQPPRLEAEGGLISPVWGAEGIPAPTCWIGTDPGGPSRAHQPQASDANREPVAERSEPALSG-LPPATMGSGDLLLSGESQVEKTKLSSSEEFPQTLSLPRTTTICSGHDADTEDDPSLADLPQALDLSQQPHSSGLSCLSQWKSVLSPGSAAQPSSCSISASSTGSSLQGHQERAEPRGGSLAKVSSSLEPVVPQEPSSVVGLGPRPQWSPQPVFSGGDASGLGRRRLSFQAEYWACVLPDSLPPSPDRHSPLWNPNKEYEDLLDYTYPLRP---GPQLPKHLDSRVPADPVLQDSGVDLDSFSVSPASTLKSPTNVSPNCPPAEATALPFSGPREPSLKQWPSRVPQKQGGMGLASWSQLASTPRAPGSRDARWERREPALRG-AKDRLTIGKHLDMGSPQLRTRDRGWPSPRPEREKRTSQSARRPTCTESRWKSEEEVESDDEYLALPARLTQVSSLVSYLGSISTLVTLPTGDIKGQSPLEVSDSDGPASFPSSSSQSQLPPGAALQGSGDPEGQNPCFLRSFVRAHDSAGEGSLGSSQALGVSSGLLKTRPSLPARLDRWPFSDPDVEGQLPRKGGEQGKESLVQCVKTFCCQLEELICWLYNVADVTDHGTAARSNLTSLKSSLQLYRQFKKDIDEHQSLTESVLQKGEILLQCLLENTPVLEDVLGRIAKQSGELESHADRLYDSILASLDMLAGCTLIPDKKPMAAMEHPCEGV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B364-1", "uniprot_id": "A0A8M2B364_DANRE", "id": "A0A8M2B364-1", "name": "", "aln": "MENKNYERWKSRIPEFIRSGHSGTLSCRTDERTRPAKVQETKDSDKERSGS------KKT----------VTLAPVSRYMTDKSLYTMRKPLISTQYQMPILKNSLTHEDSERISYKADTSKEKDKGLPTQPFRSIKEVSPCYKSSPPLSKDDLDSSMNMSDLKGWSFDEDTIFN----TSADKRSLSSPPSAFLSLTAPPVPKWTSSPKSTSRMSNHMSHLKTNVRTRAGEIMDRGRDSLINTGSSQYYNKNHPHG-------FKHMSAYQTNYWACAIPSSMPPSPNRKSPSWDPDKEYQELLDYTYPLRPNMNSTWRSSAVDHHLRTDPLLQDSGIELDRFCSS---------------SSLSCLDLSYTGTR-----RRSPRTSQKLEFRPLNQSHSKSSDGILSSSLYSSIDKVGLSFESLDCDAKSRGHYRKWG--VFSTYGSAPTFIRSTRILP---------------RPDLQDDLDEEFLRLPDQLQELQELSQQLRDISDHMSQPVITSWESLESEMTSVRSPMVQGMQEPLVEEKCDENPRSQRESVPDVPLTHQDHLLKTEEPPTSIQMISQDLNRNN-----LREVEAIMDQLRGLSVSELQGTMQTDENETKESLMQHIQAFCSNLEVLIQWLHKVVEKVELLSPPTVDLESVKSSLADYKDFQEEVQAHKPLTTDVLQTGEMLLHCMNSASPFLKDTLMLIERQSHTLEIHSEYLFSSILSAMDCLTDPTSEESSEVIS---------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :. ::. . . * .. . . .*. . . * : : ::*: . . : .: : :. *: : .:. : .: . .. . * * : .:.::. . . * :*. :. * : .... ** :. : ::: : : : *::. *. . : . :: ::*::****.:*.*:****:*:*. *:*:***::********** .. .. : :: ::*::****::** :. * .. . *. :*.* : . ** * . . :* ..: : :. ::.. * . *. * : * . * .: : *:*:* ** :* ::..* . . :. . :::. * ... : . :. . : * :. : :. . .* *. . * *: . : :: * **:* :::**..** ** **::*.: .: :.. .* .:**** *::*::::: *:.** .**:.**:**:*: . :*.*:*.* * .** ** ::: *:.***:::* *:. * ... : ", "identical_positions": 121, "similar_positions": 227, "identity": "15.86%" }, { "cls_id": "homologset.agr.RGD:1309102", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "F1M9W9-1", "uniprot_id": "F1M9W9_RAT", "id": "F1M9W9-1", "name": "", "aln": "---MAQCVQSVQELIPDSFVPCVAALCSDEAERLTRLNHLSFAELLKPFSRLTSEVHMRDPNNQLHIIKNLKIAVSNIVTQPPQPGAIGKLLNDVVSGSQPAEGLVANVITAGDYDLNISATTPWFESYRETFLQSMPASDHEFLNHYLACMLVASSAEAEPMEQFSKLSQEQHRIQHNSDYSYPKWFIP-NTLKYYVLLHDVTSGDEQRAESIYEEMKQKYGTQGCYLLKINSRAPNRASDEQIPDPWSQYLQKNSIQNQESYEDGPCTMTSSKNSDSNLLSLDGLDNEVK-DGLPDN-------CRVHPLQIDQCGDTPHNTDGSDHAKSASSVHETKKA---STGLIRGACLTLTDHDRIRQFIQEFTFRGLLPHVEKTIRQLNDQLISRKGLSRSLFSATKKWFSGSKVPEKSISELKSTSGLLYPPEAPELQIRKMADLCFLVQHYDLAYSCYHTAKKDFLNDQAMLYAAGALEMAAVSAFLQPGAPRPYPAHYMDTAIQTYRDICKNMVLAERCVLLSAEILKSQSKYAEAAALLIRLTSEQNTWKGLDSDLRSALLLEQAAHCFINMKNPMVRKYAFHMILAGHRFSKAGQKKHALRCYCQAMQVYKGKGWSLAEDHINFTIGRQSYTLRQLDNAVSAFRHILINESKQSAAQQGAFLREYLYVYKNVNQLSPDGPLPQLPLPYINSSATRVFFGHDRRPADGEKQAATHVSLDQEYDAESSQQWRELEEHVVAVANKGVIPSSFYPTQYCLNSYSDNSRFPLAVVEEPITVEVAFRNPLKVPLLLSDLSLLWKFQPKDTSGKDTE--KERVTGEP------EMIGTEVISEFLINSEESKVARLKLFPHHIGELHILGVVYNLGTIQGSVTVDGIGALPGCHTGKHSLGMSVRGRQDLEIQGPRLNNTKEEKTSVKYGPDRRLDPIVTEEMPLLEVFFIHFPTGLLCGEIRKAYVEFVNVSQCPLTALKVVSKRPEFFTFGGNTAALTPLSPSTSENCSAYKTVVTASPSLGTAFVSTASSVDFGTGTGQQLEAIPVPLPDSVLLPGASVQLPMWLRGPDEEGVHEINFLFYYESVKKQ-PKKRHRILRHTAVICTSRSLNVRATVCRSNSLEDEEGRGGNMLVFVDVENTNTSEAGVKEFHMVQVSSSSKHWQLHRSVNISENRDAKLASREKGKFCFKAVRCKQKEGDKQSSEKYTFADIIFGNEQIISSASPCADFFYRSLSSELRRTQDQLPAYPEKN--ASEGAVRLIEKCSEVDLSIVVLWKAYVVEDNKQLILEGQHHVVVRTVGKEACSHSQKQEPPEMELLKFFRPENTTVSARPSVEQLSNLIKTSLHYPESFHHPFHQKSLCLVPVTLLLSNCSKAEVDVIVDLRHKTTSPEALETHGSFTWLGQTQYKLQLKSQETHSLQLKACFVHTGVYNLGTPRVFAKLSDQVTVFETSQQNSMPALIIINNA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A286YCX6-1", "uniprot_id": "A0A286YCX6_MOUSE", "id": "A0A286YCX6-1", "name": "", "aln": "---MAQCVQSVQELIPDSFVPCVAALCSDEAERLTRLNHLSFSELLKPFSRLTSEVHMRDPNNQLHIIKNLKIAVSNIVTQPPQPGAIGKLLNDVVSGSQPAEGLVANVITAGDYDLNISATTPWFESYRETFLQSMPASDHEFLNHYLACMLVASSGEAEPMEQFSKLSQEQHRIQHNNDYSYPKWFIP-NTLKYYVLLHDVTSGDEQRAESIYEEMKQKYGTQGCYLLKINSRAPNRASDEQIPDPWSQYLQKNSIQNQESYEDGPCTMTSSKNSDSNLLSLDGLDNEVKVDGLPNN-------FRIHPLQIDQCGDPPNNTDGS-ESKSASSVHETKKA---STAVIRGACLTLTDHDRIRQFIQEFTFRGLLPHIEKTIRQLNDQLISRKGLSRSLFSATKKWFSGSKVPEKSINELKNTSGLLYPPEAPELQIRKMADLCFLVQHYDLAYSCYHTAKKDFLNDQAMLYAAGALEMAAVSAFLQPGAPRPYPAHYMDTAIQTYRDICKNMVLAERCVLLSAEILKSQSKYSEAAALLIRLTSE-------DSDLRSALLLEQAAHCFINMKSPMVRKYAFHMILAGHRFSKAGQKKHALRCYCQAMQVYKGKGWSLAEDHINFTIGRQSYTLRQLDNAVSAFRHILINESKQSAAQQGAFLREYLYVYKNVNQLSPDGPLPQLPLPYINSSATRVFFGHDRRPADGEKQAATHISLDQEYDSESSQQWRELEEHVVAVANKGVIPSSFYPTQYCLNSYSDNSRFPLAVVEEPITVEVAFRNPLKVPLLLSDLSLLWKFQPKDASGKDIEKVKERVTGEP------EMIGTEVISEFLINSEESKVARLKLFPHHIGELHILGVVYNLGTIQGSGTVDGIGALPGCHTGKHSLSMSVRGRQDLEIQGPRLNNTKEEKTSVKYGPDRRLDPIVTEEMPLLEVFFIHFPTGLLCGEIRKAYVEFVNVSKCPLTGLKVVSKRPEFFTFGGNTAALTPLSPSTSENCSAYKTVVTASPSLGTALVSTASSMDFGTGTGQQLEAIPVPLPDSVLLPGASIQLPMWLRGPDEEGVHEINFLFYYESVKKQ-PKKRHRILRHTAVICTSRSLNVRATVCRSNSLEDEEGRGGNMLVFVDVENTNTSEAGVKEFHMVQVSSSSKHWQLHKSVNISENKDAKLASREKGKFCFKAVRCKQKEGGIQSSEKYTFADIIFGNEQIISSASPCADFFYRSLSSELKKTQDQLSAYPEKHREATEGAVRLVEKCSEVDLSIVILWKAYVVEDNKQLILEGQHHVVVRTVGKEAFSHSQKEEPPEMELLKFFRPENTTVSTRPSVEQLSNLIKTSLHYPESFHHPFHQKSLCLVPVTLLLSNCSKADVDVIVDLRHKTTSPEALETHGSFTWLGQTQYKLQLKSQEMHSLQLKACFVHTGVYNLGTPRVFAKLSDHVTVFETSQQNSMPALIIINNA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y2L5-1", "uniprot_id": "TPPC8_HUMAN", "id": "Q9Y2L5-1", "name": "Trafficking protein particle complex subunit 8", "aln": "---MAQCVQSVQELIPDSFVPCVAALCSDEAERLTRLNHLSFAELLKPFSRLTSEVHMRDPNNQLHVIKNLKIAVSNIVTQPPQPGAIRKLLNDVVSGSQPAEGLVANVITAGDYDLNISATTPWFESYRETFLQSMPALDHEFLNHYLACMLVASSSEAEPVEQFSKLSQEQHRIQHNSDYSYPKWFIP-NTLKYYVLLHDVSAGDEQRAESIYEEMKQKYGTQGCYLLKINSRTSNRASDEQIPDPWSQYLQKNSIQNQESYEDGPCTITSNKNSDNNLLSLDGLDNEVK-DGLPNN-------FRAHPLQLEQSSDPSNSIDGPDHLRSASSLHETKKG---NTGIIHGACLTLTDHDRIRQFIQEFTFRGLLPHIEKTIRQLNDQLISRKGLSRSLFSATKKWFSGSKVPEKSINDLKNTSGLLYPPEAPELQIRKMADLCFLVQHYDLAYSCYHTAKKDFLNDQAMLYAAGALEMAAVSAFLQPGAPRPYPAHYMDTAIQTYRDICKNMVLAERCVLLSAELLKSQSKYSEAAALLIRLTSE-------DSDLRSALLLEQAAHCFINMKSPMVRKYAFHMILAGHRFSKAGQKKHALRCYCQAMQVYKGKGWSLAEDHINFTIGRQSYTLRQLDNAVSAFRHILINESKQSAAQQGAFLREYLYVYKNVSQLSPDGPLPQLPLPYINSSATRVFFGHDRRPADGEKQAATHVSLDQEYDSESSQQWRELEEQVVSVVNKGVIPSNFHPTQYCLNSYSDNSRFPLAVVEEPITVEVAFRNPLKVLLLLTDLSLLWKFHPKDFSGKDNEEVKQLVTSEP------EMIGAEVISEFLINGEESKVARLKLFPHHIGELHILGVVYNLGTIQGSMTVDGIGALPGCHTGKYSLSMSVRGKQDLEIQGPRLNNTKEEKTSVKYGPDRRLDPIITEEMPLLEVFFIHFPTGLLCGEIRKAYVEFVNVSKCPLTGLKVVSKRPEFFTFGGNTAVLTPLSPSASENCSAYKTVVTDATSVCTALISSASSVDFGIGTGSQPEVIPVPLPDTVLLPGASVQLPMWLRGPDEEGVHEINFLFYYESVKKQ-PKIRHRILRHTAIICTSRSLNVRATVCRSNSLENEEGRGGNMLVFVDVENTNTSEAGVKEFHIVQVSSSSKHWKLQKSVNLSENKDTKLASREKGKFCFKAIRCEKEEAATQSSEKYTFADIIFGNEQIISSASPCADFFYRSLSSELKKPQAHLPVHTEKQ--STEDAVRLIQKCSEVDLNIVILWKAYVVEDSKQLILEGQHHVILRTIGKEAFSYPQKQEPPEMELLKFFRPENITVSSRPSVEQLSSLIKTSLHYPESFNHPFHQKSLCLVPVTLLLSNCSKADVDVIVDLRHKTTSPEALEIHGSFTWLGQTQYKLQLKSQEIHSLQLKACFVHTGVYNLGTPRVFAKLSDQVTVFETSQQNSMPALIIISNV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VW22-1", "uniprot_id": "Q9VW22_DROME", "id": "Q9VW22-1", "name": "", "aln": "MLHLTGQSYNARDIIRNIFSPLIGVLSSPQADEICHRNNLSFVELLQPFAKLPNDAHFRDVSGTSVSVRGLRLNFCDVDWRPPQTILARKMLNESVTNAHNDK---TRLATIAGIDLELPTSEPWFEQWRETFLTVQFPADHEFTRHLLSCLLVLSSADPQIVETAHKLGQRVQQMQSITPQKLPKWFHPTEVLNSYVVLHEASQGDLSKAQQGFELLKSTFGDSKCFLVSINSMDS--QGAAEVPDHWATFIKRQPKSDP-NLPSTDLSAPKSPQEAVSVISMPAMQMSQLLEGVSAQDSDLAMLHPLSPMQESATEAINSKFSISSESIASQTINPNVWGNELEADAPHGGCLTSRDIDNLRHFVQDYAVRALIPYIEHLVAILAEGVTNKKGVSKSLLSATKRWFVTSKPGAG----ANNQNAVIYTNESAELQTRKLGDLYFMFGHYNLAFQSYHQAKRDFNADSAWQYYAGALEMAALSAFMLGTAQR-KTYDYMEDAIVCYLTVCKLQQFATRATLLSMECLKTARLYSEVAKQLIRMTNE-------ESDLRSALLLEQAAYCFLVTQPPMHRKYAFHIVLAGNRYSRAGQRKHAYRCYRQAYQVFQKREWSLAEDHIQYTVAKQAYMLKQLEEASRSFAHLLRPGSLQSAQQQTSFLKEYIQTQNELVKRSPELGLLPHALPQVVQSSVRVLTLVQSPSAVAPHVPATNIDINSNLTADEP-IWNKIEEMLVITAAN-NKPFVFKPSRYLYTKQQPALETPVAVQGEPIELAVTLSNSVQCRIALSEIDLLWKLTLDNDEVLSNACTYEESSDSANKIAVGAAIKTSCMASIKLAEQAEETLHFKLTPKLTGRLSILGVVCRVAAGADP-------------------AASLLGTLQFETQKIRPHNAKQSSQTVMDN---RLTIKLVPQLPAMNVSFTPVPNRLLAGEIVPVHVTLRNMGIAPIEEIYLGCDNPRCVSLLDQHSQMPLAMMSSLRNLSNDKLVKDKE------------------IRGQRVYRLLNRPGLAALDAQQVQTISLWVQAPHQAGPFTLRLLFYYSLPTVANSPIKYRLVRHIWQLQVESCLQADSTCVVSNAVTNELG--------LDVNVRNQHAVEGTEVYINSISLYSTEFKLNPDR-LHIMNSMGVSPGQAGAQCLKSS--------------------------------ICCNFQCRLLEKETQEEYKDIPS------------IKTLLHSRLSHLKILPAQHAQQVEQHMPPIHD--PHSFLTNEETVYFNTNISTEEFNASVADYVPHATLVLSWSALVAREEGQRLACGLHFIKLYKLFETGHCPAAPTASFLR--RRHSSDDTLDNRREFPLPEGALNN-------EDAWQPLADADEEDYWEPNENYVGQRCLLEDESFVMAVKA-----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P46944-1", "uniprot_id": "TRS85_YEAST", "id": "P46944-1", "name": "Trafficking protein particle complex III-specific subunit 85", "aln": "-------------------------------------MVFSYEHYMNLLFHLDNSKETVPPEIAKRIISNAIAPVITVTSTP--------------------------------------------------LFDKHIQETYKVDSLYMLLRFFGGCVSDRDQANEAKVGQHEHEVCDASDS------------------------------------------------------------------------TDSIPKNKNLEVPNLSKKGSRSRSNSLFQRDSTQSQYI-----------------------------------------------------RFTRPLGDLIETRDAN--DMLFNYHSLEVFLDNYLKLVAANTDEMVPHNLLKKSIYHS-----------------------------------------------------------------------------------------------FFSLAISSTNNLSPYETFNHPILSLIALDISNGEVYEDARDLLVNFKNLN--------------------------------------------------------HNTENFPIFMNTNEMLPVFLLCYNDDSQ-----EEFEKCQALAKKLKKQLFVESILLALWKDSFIYDENSVIQLHQP----------VMSSLEEILFFLQAP--------------------------------------------------------------------TQTTLSLALINSIYDMLDYLVYDLMIPFMKR---------------------------KVSFWEETILQPRKSLFNGAKFFKKFMNKNPVNGNHQHNSLTRDS-----------------------QGNEYFASSSSEFLMRKLADWSMMLSDFKTAYSTYESLMDDLDAFPKYLAS---------------CIEWCAVSLLMGAQSIVTVKMIKNDINPLIERALATYENCSRIQRG-----------------------KGKESNSLDVTEPVRSYETRCMILASELFLSLSNTWTSTP------------------YAIQYLETILDECKLGPCSQIMVWERLSDCYN--------LRVDPRIKHRVGAMKKDAKDTEDLRGEHKYSTDHFTDEDILSEGLTRRR----------------------------------------------------------------------------------KAAFFRLIAAKKWAEQKQWR------------------QVSWCLKDIESTYSEIKFLHGNGLILS--------------------KLKNQLNLKDVDSAPR-----------------------------------------------PSEKNLTRTSVSFIG---------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*: . :: : :* .. . . : . . : * :: ::. : :. .. . . *:.*. :.: . :. . . : . . .::. . : . * : * : :.: .:.. :: : : : : :: :.:*: : ::. ** :. : * :.. * :. *:.:.. : :: *. : :. * : : :: : * .: : .:: :.: : : .* .:: : : ::: *.: : .*: : .. . : . . *: : .. : * . . .. * : . . * . :: . : ::. ... : ..: : . : .: : :: .* * : *.. : . . . . : ::: : . * : : : : . : *: . : . . . : . . . : :: : :: . . . .:. :* .: : :. .* ..* . . . :: ", "identical_positions": 31, "similar_positions": 222, "identity": "2.11%" }, { "cls_id": "homologset.agr.RGD:1309103", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "B5DFC3-1", "uniprot_id": "B5DFC3_RAT", "id": "B5DFC3-1", "name": "Protein transport protein SEC23", "aln": "MTTYLEFIQQNEERDGVRFSWNVWPSSRLEATRMVVPVAALFTPLKERPDLPPIQYEPVLCSRTTCRAVLNPLCQVDYRAKLWACNFCYQRNQFPPTYAGISELNQPAELLPQFSSIEYVVLRGPQMPLIFLYVVDTCIEDEDLQALKESMQMSLSLLPPTALVGLITFGRMVQVHELGCEGISKSYVFRGTKDLSAKQLQEMLGLSKVPVTQATRGPQVQ--------QPPPSNRFLQPVQKIDMNLTDLLGELQRDPWPVPQGKRPLRSSGVALSIAVGLLECTFPNTGARIMMFIGGPATQGPGMVVGDELKTPIRSWHDIEKDNAKYVKKGTKHFEALANRAATTGHVIDIYACALDQTGLLEMKCCPNLTGGYMVMGDSFNTSLFKQTFQRVFTKDIHGQFKMGFGGTLEIKTSREIKISGAIGPCVSLNSKGPC-VSENEIGTGGTCQWKICGLSPTTTLAIYFEVVNQHNAPIPQGGR---------GAVQFVTQYQHSSGQRRIRVTTIARNWADAQTQIQNIAASFDQEAAAILMARLAIYRAETEEGPDVLRWLDRQLIRLCQKFGEYHKDDPNSFRFSETFSLYPQFMFHLRRSPFLQVFNNSPDESSYYRHHFMRQDLTQSLIMIQPILYAYSFSGPPEPVLLDSSSILADRILLMDTFFQILIYHGETIAQWRKSGYQDMPEYENFRHLLQAPVDDAQEILHSRFPMPRYIDTEHGGSQARFLLSKVNPSQTHNNMYAWGQE--------SGAPILTDDVSLQVFMDHLKKLAVSSAA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q01405-1", "uniprot_id": "SC23A_MOUSE", "id": "Q01405-1", "name": "Protein transport protein Sec23A", "aln": "MTTYLEFIQQNEERDGVRFSWNVWPSSRLEATRMVVPVAALFTPLKERPDLPPIQYEPVLCSRTTCRAVLNPLCQVDYRAKLWACNFCYQRNQFPPTYAGISELNQPAELLPQFSSIEYVVLRGPQMPLIFLYVVDTCIEDEDLQALKESMQMSLSLLPPTALVGLITFGRMVQVHELGCEGISKSYVFRGTKDLSAKQLQEMLGLSKVPVTQATRGPQVQ--------QPPPSNRFLQPVQKIDMNLTDLLGELQRDPWPVPQGKRPLRSSGVALSIAVGLLECTFPNTGARIMMFIGGPATQGPGMVVGDELKTPIRSWHDIEKDNAKYVKKGTKHFEALANRAATTGHVIDIYACALDQTGLLEMKCCPNLTGGYMVMGDSFNTSLFKQTFQRVFTKDIHGQFKMGFGGTLEIKTSREIKISGAIGPCVSLNSKGPC-VSENEIGTGGTCQWKICGLSPTTTLAIYFEVVNQHNAPIPQGGR---------GAVQFVTQYQHSSGQRRIRVTTIARNWADAQTQIQNIAASFDQEAAAILMARLAIYRAETEEGPDVLRWLDRQLIRLCQKFGEYHKDDPNSFRFSETFSLYPQFMFHLRRSPFLQVFNNSPDESSYYRHHFMRQDLTQSLIMIQPILYAYSFSGPPEPVLLDSSSILADRILLMDTFFQILIYHGETIAQWRKSGYQDMPEYENFRHLLQAPVDDAQEILHSRFPMPRYIDTEHGGSQARFLLSKVNPSQTHNNMYAWGQE--------SGAPILTDDVSLQVFMDHLKKLAVSSAA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15436-1", "uniprot_id": "SC23A_HUMAN", "id": "Q15436-1", "name": "Protein transport protein Sec23A", "aln": "MTTYLEFIQQNEERDGVRFSWNVWPSSRLEATRMVVPVAALFTPLKERPDLPPIQYEPVLCSRTTCRAVLNPLCQVDYRAKLWACNFCYQRNQFPPSYAGISELNQPAELLPQFSSIEYVVLRGPQMPLIFLYVVDTCMEDEDLQALKESMQMSLSLLPPTALVGLITFGRMVQVHELGCEGISKSYVFRGTKDLSAKQLQEMLGLSKVPLTQATRGPQVQ--------QPPPSNRFLQPVQKIDMNLTDLLGELQRDPWPVPQGKRPLRSSGVALSIAVGLLECTFPNTGARIMMFIGGPATQGPGMVVGDELKTPIRSWHDIDKDNAKYVKKGTKHFEALANRAATTGHVIDIYACALDQTGLLEMKCCPNLTGGYMVMGDSFNTSLFKQTFQRVFTKDMHGQFKMGFGGTLEIKTSREIKISGAIGPCVSLNSKGPC-VSENEIGTGGTCQWKICGLSPTTTLAIYFEVVNQHNAPIPQGGR---------GAIQFVTQYQHSSGQRRIRVTTIARNWADAQTQIQNIAASFDQEAAAILMARLAIYRAETEEGPDVLRWLDRQLIRLCQKFGEYHKDDPSSFRFSETFSLYPQFMFHLRRSSFLQVFNNSPDESSYYRHHFMRQDLTQSLIMIQPILYAYSFSGPPEPVLLDSSSILADRILLMDTFFQILIYHGETIAQWRKSGYQDMPEYENFRHLLQAPVDDAQEILHSRFPMPRYIDTEHGGSQARFLLSKVNPSQTHNNMYAWGQE--------SGAPILTDDVSLQVFMDHLKKLAVSSAA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7SZE5-1", "uniprot_id": "SC23A_DANRE", "id": "Q7SZE5-1", "name": "Protein transport protein Sec23A", "aln": "MATFQEFIQQNEDRDGVRFSWNVWPSSRLEATRMVVPVASLFTPLKERPDLPPIQYEPVLCSRATCRAVLNPLCQVDYRAKLWACNFCYQRNQFPPTYAGISEVNQPAELLPQFSTIEYVVQRGPQMPLNFLYVVDTCMEDDDLQALKESLQMSLSLLPPTALVGLITFGRMVQVHELGCEGISKSYVFRGTKDLNAKQLQEMLGLTKPAAAQAGRGPQQP--------QVPPSNRFLQPVQKIDMNLTDLLGELQRDPWPVTQGKRPLRSLGVALSIAVGLLECTFPNTGARIMAFIGGPATQGPGMVVGDELKTPIRSWHDIEKDNAKFMKKATKHYEALANRAAANGHIIDIYACALDQTGLLEMKCCTNYTGGYMVMADSFNTSLFKQTFQRVFTKDVQGCFKMALAGTLEIKTSREIKISGAIGPCVSLNAKGPC-VSENEMGTGGTSQWKICGLDPNTTLGFYFEVVNQHNAPIPQGGR---------GAIQYVTQYQHSSGQRRIRVTTIARNWADAQSQIQSIAASFDQEAAAILMARLAVYKAETEEGPDVLRWLDRQLIRLCQKFGDYHKEDPNSFRFSETFSLYPQFMFHLRRSPFLQVFNNSPDESTYYRHQFMRQDLTQSLIMVQPILYAYSFNGPPEPVLLDSSSILPDRILLMDTFFQILIYHGETVSQWRKAGYQDMPEYENFRHLLQAPVDDAQELLHTRFPMPRYIDTEHGGSQARFLLSKVNPSQTHNNMYAWGQE--------SGAPILTDDVSLQVFMDHLKKLAVSSAA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4K5Z8-1", "uniprot_id": "A0A0B4K5Z8_DROME", "id": "A0A0B4K5Z8-1", "name": "Protein transport protein SEC23", "aln": "MTTYEEFIQQNEDRDGVRLTWNVWPSSRIEASRLVVPLACLYQPLKERPDLPPIQYEPVLCTRSNCRAILNPLCQVDYRAKLWVCNFCFQRNPFPPQYAAISEQHQPAELIPGFSTIEYTITRAPTMPPVFIFLVDTCMDEEELDALKDSLQMSLSLLPTNALVGLITFGKMIQVHELGAEGCSKSYVFRGTKDLTAKQVQDMLGIGRGAAPGPQQQQHLPGQPAGAAAPVPPAHRFLQPIGQCDAALGDLLSELQRDPWPVPQGKRYLRSTGAALSIAVGLLECTYPNTGGRIMTFVGGPCSQGPGQVVDDELKHPIRSHHDIHKDNVRFMKKAIKHYDALALRAATNGHSVDIYSCALDQTGLLEMKQLCNSTGGHMVMGDSFNSSLFKQTFQRVFARDGRNDLKMAFNATLEVKCSRELKISGGIGSCVSLNVKSPS-VSDVEIGMGNTVQWKLCTLNPSSTVAYFFEVVNQHAAPIPQGGR---------GCIQFITQYQHPSGQRRIRVTTLARNWADATSNVHHISAGFDQEAAAVLMARMVVYRAETDEGPDILRWVDRQLIRLCQKFGEYSKDDPNSFRLSQNFSLFPQFMYHLRRSQFLQVFNNSPDETTFYRHMLMREDLTQSLIMIQPILYSYSFNGPPEPVLLDTASIQADRILLMDTFFQILIYHGETIAQWRALKYQDMPEYENFKQLLQAPVDDAQEILQTRFPMPRYIDTEHGGSQARFLLSKVNPSQTHNNMYAYGQAPIGQVTVDGGAPVLTDDVSLQLFMEHLKKLAVSTTT", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P15303-1", "uniprot_id": "SEC23_YEAST", "id": "P15303-1", "name": "Protein transport protein SEC23", "aln": "-----MDFETNEDINGVRFTWNVFPSTRSDANSNVVPVGCLYTPLKEYDELNVAPYNPVVCSGPHCKSILNPYCVIDPRNSSWSCPICNSRNHLPPQYTNLSQENMPLELQS--TTIEYITNKPVTVPPIFFFVVDLTSETENLDSLKESIITSLSLLPPNALIGLITYGNVVQLHDLSSETIDRCNVFRGDREYQLEALTEMLTGQKPTGPGGAASHLPN---AMNKVTPFSLNRFFLPLEQVEFKLNQLLENLSPDQWSVPAGHRPLRATGSALNIASLLLQGCYKNIPARIILFASGPGTVAPGLIVNSELKDPLRSHHDIDSDHAQHYKKACKFYNQIAQRVAANGHTVDIFAGCYDQIGMSEMKQLTDSTGGVLLLTDAFSTAIFKQSYLRLFAKDEEGYLKMAFNGNMAVKTSKDLKVQGLIGHASAVKKTDANNISESEIGIGATSTWKMASLSPYHSYAIFFEIANTAANSNPMMSAPGSADRPHLAYTQFITTYQHSSGTNRIRVTTVANQLLPFG--TPAIAASFDQEAAAVLMARIAVHKAETDDGADVIRWLDRTLIKLCQKYADYNKDDPQSFRLAPNFSLYPQFTYYLRRSQFLSVFNNSPDETAFYRHIFTREDTTNSLIMIQPTLTSFSMEDDPQPVLLDSISVKPNTILLLDTFFFILIYHGEQIAQWRKAGYQDDPQYADFKALLEEPKLEAAELLVDRFPLPRFIDTEAGGSQARFLLSKLNPSDNYQDMARGGST-----------IVLTDDVSLQNFMTHLQQVAVSGQA", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: **: :***::***:**:* :*. ***:..*: **** :* *:**:*: . *:::*** * :* * . * * :* .** :** *: :*: : * ** . ::*** : :* *:::** : ::*::**:*: ******..**:****:*.::*:*:*..* .:. **** :: : : :** : . . . :**: *: : : * :** :*. * *.*. *:* **: * **.** **: : * .**: * .** : .** :*..*** *:** ***..*:.:. **. *.:: :* *.*:.** :**:: . ** *: *** : *** ::: *:*.:::***:: *:*::* .. :**.: ..: :* *:::*:.* ** . ::: ... :*: *:* * * **:. *.* : . :**:.* . * . . *::* ***.** .******:*.: *:*.*******:****:.:::***::*.*::**:** **:****:.:* *:**.***:: .***:*** ::**** **.********:::*** : *:* *:****:** * ::*:.. *:*****: *: .: ***:**** ******* ::*** *** *:* :*: **: * :* *:* ***:**:**** ***********:***:.:::* *. :******** ** **:::*** :", "identical_positions": 325, "similar_positions": 235, "identity": "41.09%" }, { "cls_id": "homologset.agr.RGD:1309104", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZU88-1", "uniprot_id": "D3ZU88_RAT", "id": "D3ZU88-1", "name": "", "aln": "MGCASAKHVATVQNEEEAQKGK----SYQNGDVFGDEYRIKPVEEVKYMKNGAEEEQKIAARNQENLEKSASSNTRLKTNKEIPGFVHQPRANMHISESQQEFFRMLDEKIEKGRDYCSE-EEDIT-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K207-1", "uniprot_id": "CA021_MOUSE", "id": "Q8K207-1", "name": "Uncharacterized protein C1orf21 homolog", "aln": "MGCASAKHVATVQNEEEAQRGK----SYQNGDVFGDEYRIKPVEEVKYMKNGAEEEQKIAARNQENLEKSASSNTRLKTNKEIPGLVHQPRANMHISESQQEFFRMLDEKIEKGRDYCSE-EEDIT-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H246-1", "uniprot_id": "CA021_HUMAN", "id": "Q9H246-1", "name": "Uncharacterized protein C1orf21", "aln": "MGCASAKHVATVQNEEEAQKGK----NYQNGDVFGDEYRIKPVEEVKYMKNGAEEEQKIAARNQENLEKSASSNVRLKTNKEVPGLVHQPRANMHISESQQEFFRMLDEKIEKGRDYCSE-EEDIT-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M9PET2-1", "uniprot_id": "M9PET2_DROME", "id": "M9PET2-1", "name": "", "aln": "MGCGQSKIHLYPRKSKSKANGKKGGHADSDAETDEDEGHIEDAEKAQ-QRDREKHDESEELSNKDIQESDEDVAVSLLRAKNLSLLQSQ-----EISSSQQNFFRMLDKKIDEGPDYDSASETEIALEEARLNALRQHWESASITASICSSASRSLQTTPIRQVQVPLKQPPRGAGLLIQPSSASAVTASTSSSSSSTIVALPTTEYLPQHVLTGRQVVQQQQQQQQQQAAVLYQQQQQQLILLPQLDPNVVNTSTAAAAAQLVQLQQQHQQQQQQLQLQQQQQLQLNQQQQQQLYQQQQQQYLLTLPAGSKPQSVSPKRLIYGGPAATTLLCATGDVHFSIKCNAPETYEPPTAPHSQIQQQQPPPPPPGAYYGEMMHGVQAAPAAEYKFPPAISVQRLAPQVQRQLRETQELIKDSCPQLYAAGYGSPGPPIRNPSRNPTRTRPTLETQFSQELS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***..:* ::.:. .** .:.:. ** :*: .*:.: :: :.::. *:: *.. . . * *::. : * .**.***:******:**::* ** * * :*: ", "identical_positions": 34, "similar_positions": 45, "identity": "7.44%" }, { "cls_id": "homologset.agr.RGD:1309105", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5RI15-1", "uniprot_id": "COX20_HUMAN", "id": "Q5RI15-1", "name": "Cytochrome c oxidase assembly protein COX20, mitochondrial", "aln": "MAAPPEPGEPEERKSLKLLGFLDVENTPCARHSILYGSLGSVVAGFGHFLFTSRIRRSCDVGVGGFILVTLGCWFHCRYNYAKQRIQERIAREEIKKKILYEGTHLDPERKHNGSSSN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0KZQ7-1", "uniprot_id": "A0ABK0KZQ7_RAT", "id": "A0ABK0KZQ7-1", "name": "Cytochrome c oxidase assembly protein COX20, mitochondrial", "aln": "MAAASEPHEPE-KKPFKLLGILDVENTPCARESILYGSLGSIVTGLGHFLVTSRIRRSCDVGVGGFILVTLGCWFHCRYNFAKQRIQERIAREGIKNKILYESTHLDPERKTKSSNSS", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***..** *** :*.:****:**********.*********:*:*:****.*****************************:************ **:*****.******** :.*.*.", "identical_positions": 96, "similar_positions": 18, "identity": "81.36%" }, { "cls_id": "homologset.agr.RGD:1309106", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XIU7-1", "uniprot_id": "CA105_RAT", "id": "Q5XIU7-1", "name": "Uncharacterized protein C1orf105 homolog", "aln": "MEKRELKTFVPKFDKIPWLSEASVVNKPLILSIPRRY--RSSIVLTSYKKDMYLPHLLEDSDFISKARKNEHENLLPRNKQLCSTCRGYQEMKTLQPKIFKIPDHREPSPQNSVNHGEVSLHS---QEQQLHACNDIPTESIRYRLPILGPRTAVFHRLLSDAYKTPQDTQYCAFPKKKGMSKTVKQITTPHAALYPCRSYSAI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E0CXC6-1", "uniprot_id": "E0CXC6_MOUSE", "id": "E0CXC6-1", "name": "", "aln": "MEKRELKAFVPKFDKIPWLSEASLVNKPLILSIPRRY--HSSFVLTSYKKDMYLPHLLENPDFLSKARKNEHENLSPRNKQLCATCRGYQKVKTVQPKTFIIPDHQKPPSQNSVNHREVSLHS---QVQQLNSYNDIPTESISYRLPILGPRTAVFHRLLSSAYENPRDTQHRAFPRKKGMSKTVKQ-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95561-1", "uniprot_id": "CA105_HUMAN", "id": "O95561-1", "name": "Uncharacterized protein C1orf105", "aln": "MEKRELKASVPKFDKIPWLSEASLVNKPLVLSLPRRYPHTSATFLTSSKKNMNLPILFQVPDVLSKARRNQCDSMLLRNQQLCSTC---QEMKMVQPRTMKIPDDPKASFENCMSY-RMSLHQPKFQTTPEPFHDDIPTESIHYRLPILGPRTAVFHGLLTEAYKTLKERQRSSLPRKEPIGKTTRQ-----------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*******: **************:*****:**:**** *: .*** **:* ** *:: .*.:****:*: :.: **:***:** *::* :**: : ***. :.. :*.:.: .:***. * :******* ************** **:.**:. :: * ::*:*: :.**.:* ", "identical_positions": 98, "similar_positions": 51, "identity": "48.04%" }, { "cls_id": "homologset.agr.RGD:1309107", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q80Y19-1", "uniprot_id": "RHGBA_MOUSE", "id": "Q80Y19-1", "name": "Rho GTPase-activating protein 11A", "aln": "MWDQRLVRLALLQQLRAVYGIKVKGGRGQCDRRRHETAATEIKGKVFGVPFNSLPHSVVPEFGHIPSFLVDACASLKEHIHTEGLFRKSGSVVRLKALKSKLDQGEACLSSALPCDVAGLLKQFFRELPEPVLPADLHEALFKAQQLGAEERNKATLLLSCLMANPTVDILRYFFNFLKSVSLRASENKMDSSNLAVIFAPNLLQTSEGHEKMSANTEKKLRLQAAVVQTFIDCASDIGRVPDFILEKIPAMLGIDGLCTTPSLEGF-EGDFETPGECKRKRRQSVGDFVNGALNKLKSSRTPSITPQQDRTAQASASPLILTPSVKRKLPGESSHAFSSKKRKSIKHNLNFELLPSHFFSSNSTPVSVHLDTSPDGSSQTSLSPIAMSGNHLVSTEL-RRSKRIASKKVYRVESGKAGCFSPKVSRKEKTRRSLRLKFSLGKN-RDSDGCSVINRYENVGRRLANQQNLKSRIDSVKTGLLFSPDIDERLLKKGSEKISKSEEHLLTPDQLDGTGYRMSWTEPSNSSFQDMSANGTSPIMQNLEVKSFSLEPDITVEKSPVVSCELRPSTFHSQPDSSVL--SLSGDEGNLASETLQKIQKAFSESGSDLHMVINHEQSSVTNTG--------------EE--VEFRDVTVTESKGHDGSCAGEEENCPSERNFSPDQSPEFAREADEECYSTQMKVECEG-LHSETPKADPLILQAFPGEEPAEEPQSPRNQLS-TPSRGNENGGE-SAGASGAPGED--------ESTCSVAVLSKPRPQRLSRQQSLVEKCDSVAPGALQVTEHGKVSDHIQWFNKLSLNEPNRGKVKSPLKFQRTPVRQSVRRINSLLEYGRQPVRQKLAIFGDAASPLVKSVSCDSALPSCVQNTSKGPTAPLITSGLEAQKSTSCN--------KSSVELTSKSFTKMKRHPDPLSASLGTPRLCKQENKSNGHIKFPLDDLTNHERLKFVVNNNVAFSPGMKNRVVRKPSEKERVWYKGSPKNPIGKTQLLPTSKPVDL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3Z951-1", "uniprot_id": "D3Z951_RAT", "id": "D3Z951-1", "name": "Rho GTPase-activating protein 11A", "aln": "MWDQRLVRLALLQQLRAVYGIKVKGGRGQCDRRRQETAATEIRGKIFGVPFNSLPHSVVPEYGHIPSFLVDACTSLKEHIHTEGLFRKSGSVIRLKALKSKLDHGEACLSSALPCDVAGLLKQFFRELPEPVLPADLHEALFKAQQLGAEERNKATLLLSCLMADPTVDVLRYFFNFLKSVSLRASENKMDSSNLAVIFAPNLLQTSEGHEKMSANTEKKLRLQAAVVQTLIDYASDIGRVPDFILEKIPAMLGIDGLCTTPSLEGF-EGDYETPGECKRKRRQSVGDFVNGALNKLKSSRTPSITPQQDRTAQAPVSPLILTPSVKRKLPGETSHTLSSKKRKSIKNNLNFELLPSHLFSSNSTPVSVHFDTSPEGSSQSSLSPIAMSGNHLTSTDL-RRSKRIASKKVYRVESGKAGCFSPKVTRKEKVRRSLRLKFSLRKN-RDSNGCSVINRHENVGRRLANQQNLKNRIESVKTGLLFSPDIDERLLKKGSEKISKSEEHLLTPDQLDGTGYRMSWTEPSNSSFQDMSANGTSPIMQNLEVKSFSLESNITVEKSPVVSCELRPSTFHSQPNSSVLGRSLSGDEGNLAFETLQKIQKAFSESGSDLHTAVNHEQSSVTNVG--------------EE--GESRD--VSESKGHDGSYTGQDENYASERNLSPSQSPELAREASEECHSTQMKVGCES-LHSETPRAD-LLQQAFPSEEPTKETQSPGSQLDTTPSQGDENVVEENSGACEAPEENDAQS--LKQSTCSVTVISKPRAQRLARQRSLVEKCDSAVPGGPQMTEHGKVSDHIQWFNKLSLNEPNRGKVKSPLKFQRTPVRQSVRRINSLLEYGRQPVRQKLAVFGDAASPLVKSVSCDSALPSCVQSTSKGPCVPHTKPGLEAQKCTSCD--------KSSVELTSKSFTKMKRHPDPLNASLATTRLCKQENKSDVQIKFPLDDLTNHDRLKFVVNNNVDFPPGIKNRVLKKPLEKERVWYKGSPKNPIGKTQLLPTSKPVDL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P4F7-1", "uniprot_id": "RHGBA_HUMAN", "id": "Q6P4F7-1", "name": "Rho GTPase-activating protein 11A", "aln": "MWDQRLVRLALLQHLRAFYGIKVKGVRGQCDRRRHETAATEIGGKIFGVPFNALPHSAVPEYGHIPSFLVDACTSLEDHIHTEGLFRKSGSVIRLKALKNKVDHGEGCLSSAPPCDIAGLLKQFFRELPEPILPADLHEALLKAQQLGTEEKNKATLLLSCLLADHTVHVLRYFFNFLRNVSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNTEKKLRLQAAVVQTLIDYASDIGRVPDFILEKIPAMLGIDGLCATPSLEGFEEGEYETPGEYKRKRRQSVGDFVSGALNKFKPNRTPSITPQEERIAQLSESPVILTPNAKRTLPVDSSHGFSSKKRKSIKHNFNFELLPSNLFNSSSTPVSVHIDTSSEGSSQSSLSPVLIGGNHLITAGVPRRSKRIAGKKVCRVESGKAGCFSPKISHKEKVRRSLRLKFNLGKNGREVNGCSGVNRYESVGWRLANQQSLKNRIESVKTGLLFSPDVDEKLPKKGSEKISKSEETLLTPERLVGTNYRMSWTGPNNSSFQEVDANEASSMVENLEVEN-SLEPDIMVEKSPATSCELTPSNLNNKHNSNITSSPLSGDENNMTKETLVKVQKAFSESGSNLHALMNQRQSSVTNVGKVKLTEPSYLEDSPEENLFETNDLTIVESKEKYEHHTGKGEKCFSERDFSPLQTQTFNRETTIKCYSTQMKMEHEKDIHSNMPKDY-LSKQEFSSDEEIKKQQSPKDKLN-NKLKENENMMEGNLPKCAAHSKDEARSSFSQQSTCVVTNLSKPRPMRIAKQQS-LETCEKTVSESSQMTEHRKVSDHIQWFNKLSLNEPNRIKVKSPLKFQRTPVRQSVRRINSLLEYSRQPTGHKLASLGDTASPLVKSVSCDGALSSCIESASKDSSVSCIKSGPKEQKSMSCEESNIGAISKSSMELPSKSFLKMRKHPDSVNASLRSTTVYKQKILSDGQVKVPLDDLTNHDIVKPVVNNNMGISSGINNRVLRRPSERGRAWYKGSPKHPIGKTQLLPTSKPVDL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*************:***.******* ********:******* **:******:****.***:***********:**::**************:******.*:*:**.***** ***:**************:*********:******:**:**********:*: **.:********:.****:*****************************:***************:** *************************:******* **::***** ************.*****:*..********::* ** . **:****..**.** ::** :*********:*:*******::*.*.*******:***.:****:****: :.**** :: : *******.*** *************:::***.********.* ** *: :*** :**:*.** ******.**.**:***********:**:* ************ ****::* **.****** *.*****::.** :*.:::****:. ***.:* *****..**** **.::.: :*.: .*****.*:: *** *:*********:** :*:.******.* ** * .* : *** : :*: *: ***::** *: : **: :*:*****: * :**: *: * * *..:* :: *** .:*. . : :** * . . * :: :*** *: :****. *:::*:* :*.*:.... . *:*** ******************* **************************.***. :*** :**:***********.**.**::.:**.. .. ..* : **. **: ***:**.**** **::***.:.*** :. : **: *: ::*.********: :* *****: :..*::***:::* *: *.*******:****************", "identical_positions": 670, "similar_positions": 212, "identity": "65.24%" }, { "cls_id": "homologset.agr.RGD:1309108", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "F1LZA7-1", "uniprot_id": "F1LZA7_RAT", "id": "F1LZA7-1", "name": "", "aln": "MPLWMNKYKPVPKRSSRSPVHHTNLRTPPSGRAFKEEDFN-LISKDSLESDSESLPREAKFWSDIKDQIQDKDMEPDSLEEDSSS------ETEEAA-----HGTNREGLGAQGAGANHSHHQVEDKYSDLRYDPNWKNKKEEGQLLAVEALPESADSSSDNLPGAPLYPSREPSMRLSVGKGKEKRSPQSEASLLGSEFLSPKYECGTRQNEFFSELSDSDQEDQEEKSSDLSPYLKSSSSHNEVFLPGSRGPRRRKSRQYFVEKNKLTLGLPAPKTDSYLQLHNKKRGETRLEQISYPIRDAGKMTVQDDKGVENTFMDPEDKWHQRAKQLKNYQEHLSQCEDTKSGNVPRGQSSNAANVQQPSRRTAKARVQKQKKYQNGLKSLGTKEQVVSQNNQNNSLQQPQTQRLPMDTSSKHEPAAQMTASNPNLQDPRTL-THNPKVTSDPFFPPKETFDRVVYKNSV---LGLNTNKRRGHRYKEEKRILYQQQPIYIFSDGDLQDFNELSHRHESLSQRGPQSDYRMNTHRSRSTKTKKPSKEPEAETKYKNIEMLWKLHSSSDMEPVSASPDSRLAQIMEQHQQALLQLAEVQPSEGSLSSTVFPPILSRVESESQLDSERSHKHQMRMARSNSEGYLLQLEKGKRHRKRSQSRTKSSKLKGYQKRDVKLGGLGPDFASIRDKMQTLLQQKEYAKQVKEYNMKTLSVLSKPQTSKTDSKSTISRKKALDYAKTIPKPKPPNLPYQTMKKTNNSKHSEKEGSLPEISLLEILQSRHEREKQAVAAFKVLHIV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q793-1", "uniprot_id": "JHY_MOUSE", "id": "E9Q793-1", "name": "Jhy protein", "aln": "----MNKYKPVPKLSSQSPVHHTNLRIPPSGRPFKKEDFLNLISKDSLESDSESLPQEAKSWSDIKDQIQDKDMEPDSLEEDSPS------ETEEAVNRKAAHNTNREDLSAHDAGVNHSQHQVEDKYSDLRYDPNWKNKREEGQPLAGEALPGSADSSSENLPLAPLYPSREPSMGLSAGKGKEKKSPQSEASLLGSEFLSPKYERSTRQNGFFSELSDSDQE---EKSSGLSQYLKSSSSHNDVFLPGSRGPRRRKSKQYFVEKNKLTLGLPMPKTDSYLQLHNKKRGETRLEQISYPVRDTDKMTVQNDKEVENTFMDPEDKWHQRAKQLKNYQEHLSQYEDTKSGNVPRGQSSDAANGQQPSRRTAKARVRKQRKHQKGLKSLGTKELVVSQNNQNNPFQQPQNQRQTADASAKHELAAQTNASNPNLQDARTL-THNPKVTSDSFVSPKQALDRALYKNSI---SGLNANKRRGHR-REEERILYQPQPIYVFSDTHLQDFNELPHRHESPSQRAPQSDHHMNTHR--STKTKKPAKQPQAETKYKNIEMLWKFHSSSDMEPASASPDSRLAQIMEQHQQALMQLAEVQPSEGSLASIILPPILSRVESESQLNSERSHRHQVKMARSNSEGYLLQLERGKRHRKRSS--TKSSKLKGYQKRDVKLGGLGPDFASVRDKMQMLMQQKEYAQQVKDYNMKALSILSKPQTSKTESKSAISRKKALDYAKTIPKPKPPNLPDQTAKKTKNSRHSEKEGGLPEISLLEILQSRHEREKQAVAAFKVLHIV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6NUN7-1", "uniprot_id": "JHY_HUMAN", "id": "Q6NUN7-1", "name": "Jhy protein homolog", "aln": "----MSKRKLIPKLSIQSPVLHTNLNVQSTHPPLKKEDLH-RISKDSLESDSESLTQEIMCHSEFDDRIRGNGMEPDSLDEEESPRWGSLHEMEEEASGKAAQMAREQNHHTWDQGANNRQQPIEDKYSDLRYDPNWKSKKEEGQLLSVEALPESTDSSLENLPLAPLYPSQETSMELSGGKGEQKESPQSAASLLGSEFLSPNYEHGARRSKPFSELSDSDLE---EKSSSLSPYVKSSSSHNEVFLPGSRGPRRRKSKQHFVEKNKLTLGLPTPKTDSYLQLHNKKRGESHPEQISYPVRVTDKTSIQNAKEMENAAIDPEDKWHQRAQQLKNYQEHWSQYESTKSSNVPRGQPSDMVNDHQPSRRPAKLKIRKQCKHQNGLKSSTTEEVTASQGNQNNPPRQQQNQNKPLDTSTKPESIVIMHASNNDVQASRALRSHNLKETSNTFAPPKQAFDKVLSKNSTGCDSGLNVNKERGHKDQEEKRFSYQQ--LHTLSDMDLNNLNELSKRHVLLSQKGSQFVYHINTHG--STKNKKQLKQPYTETKYRNLEMLWKFHSSSDSQTVRASPDSWLTQIMEQHQQALVQLTDVQPSEGALSSVTLPPILSRVESESQLSSERSQRNQVKISRSNSEGYLFQLEKGKKHKKRSS--SKNTKLKGYQKRDVKLGGLGPDFESIRDKTQKLIQQKEYAKQVKEYNMKTLSILSKPQTEKTQKKSAIPRQKALEYAKTIPKPKPSNLTHQASKEQKNPTYAGKEESLPEISLLEILQNRHEREKQAVAAFKVLHIV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.* * :** * :*** ****. .: .:*:**: *************.:* *::.*:*:.:.******:*:... * ** . : :..:. : . *.*: :: :**************.*:**** *: **** *:*** :*** ******:*.** ** ***::*.**** ***********:** .:*:. ******** * ****.** *:*******:**************:*:************ ****************:: ******:* :.* ::*: * :**: :**********:******** ** *.***.******.*: .* :*****.** :::** *:*:**** *:* ..**.****. :* *.*. . *:*:* * . *** ::* .*:* :** * **:.* .**:::*:.: *** ***.**.***: :**:*: ** :: :** .*:::***.:** **:..* :::*** ***.** *:* :****:*:*****:***** :.. ***** *:**********:**::******:*:* :*************.****:::*::::********:***:**:*:***. :*.:******************* *:*** * *:******:***:****:**:******.**:.**:*.*:***:**********.**. *: *: :*. :: ** .***********.******************", "identical_positions": 479, "similar_positions": 185, "identity": "60.48%" }, { "cls_id": "homologset.agr.RGD:1309109", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AH26-1", "uniprot_id": "A0A8I6AH26_RAT", "id": "A0A8I6AH26-1", "name": "General transcription and DNA repair factor IIH helicase subunit XPD", "aln": "MTGRLSQWHREEGGALGHAPSLNIQEAGEWTPGQAAMKLNVDGLLVYFPYDYIYPEQFSYMLELKRTLDAKGHGVLEMPSGTGKTVSLLALIVAYQRAYPLEVTKLIYCSRTVPEIEKVIEELRKLLSFYEQQEGEKLPFLGLALSSRKNLCIHPEVTPLRFGKDVDGKCHSLTASYVRAQYQQD--ASLPHCRFYEEFDTHGRQVPLPAGIYNLDDLKALGQRQGWCPYFLARYSILHANVVVYSYHYLLDPKIADLVSKELARKAVVVFDEAHNIDNVCIDSMSVNLTRRTLDRCQSNLDTLQKTVLRIKETDEQRLRDEYRRLVEGLREASAARET-DAHLANPVLPDEVLQEAVPGSIRTAEHFLGFLRRLLEYVKWRLRVQHVVQESPPAFLSGLAQRVCIQRKPLRFCAERLRSLLHTLEIADLADFSPLTLLANFATLVSTYAKGFTIIIEPFDDRTPTITNPILHFSCMDASLAIKPVFERFQSVIITSGTLSPLDIYPKILDFHPVTMATFTMTLARVCLCPMIIGRGNDQVAISSKFETREDIAVIRNYGNLLLEMSAVVPDGIVAFFTSYQYMESTVASWYEQGILENIQRNKLLFIETQDGAETSVALEKYQEACENGRGAILLSVARGKVSEGIDFVHHYGRAVIMFGVPYVYTQSRILKARLEYLRDQFQIRENDFLTFDAMRHAAQCVGRAIRGKTDYGLMVFADKRFARADKRGKLPRWIQEHLTDSNLNLTVDEGVQVAKYFLRQMAQPFHREDQLGLSLLSLEQLQ-------------SEETLQRIEQIAQQL-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08811-1", "uniprot_id": "ERCC2_MOUSE", "id": "O08811-1", "name": "General transcription and DNA repair factor IIH helicase subunit XPD", "aln": "------------------------------------MKLNVDGLLVYFPYDYIYPEQFSYMLELKRTLDAKGHGVLEMPSGTGKTVSLLALIVAYQRAYPLEVTKLIYCSRTVPEIEKVIEELRKLLSFYEQQEGEKLPFLGLALSSRKNLCIHPEVTPLRFGKDVDGKCHSLTASYVRAQYQQD--ASLPHCRFYEEFDIHGRQMPLPAGIYNLDDLKALGQRQGWCPYFLARYSILHANVVVYSYHYLLDPKIADLVSKELARKAVVVFDEAHNIDNVCIDSMSVNLTRRTLDRCQSNLDTLQKTVLRIKETDEQRLRDEYRRLVEGLREASVARET-DAHLANPVLPDEVLQEAVPGSIRTAEHFLGFLRRLLEYVKWRLRVQHVVQESPPAFLSGLAQRVCIQRKPLRFCAERLRSLLHTLEIADLADFSPLTLLANFATLVSTYAKGFTIIIEPFDDRTPTIANPVLHFSCMDASLAIKPVFERFQSVIITSGTLSPLDIYPKILDFHPVTMATFTMTLARVCLCPMIIGRGNDQVAISSKFETREDIAVIRNYGNLLLEMSAVVPDGIVAFFTSYQYMESTVASWYEQGILENIQRNKLLFIETQDGAETSVALEKYQEACENGRGAILLSVARGKVSEGIDFVHHYGRAVIMFGVPYVYTQSRILKARLEYLRDQFQIRENDFLTFDAMRHAAQCVGRAIRGKTDYGLMVFADKRFARADKRGKLPRWIQEHLTDSNLNLTVDEGVQVAKYFLRQMAQPFHREDQLGLSLLSLEQLQ-------------SEETLQRIEQIAQQL-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P18074-1", "uniprot_id": "ERCC2_HUMAN", "id": "P18074-1", "name": "General transcription and DNA repair factor IIH helicase subunit XPD", "aln": "------------------------------------MKLNVDGLLVYFPYDYIYPEQFSYMRELKRTLDAKGHGVLEMPSGTGKTVSLLALIMAYQRAYPLEVTKLIYCSRTVPEIEKVIEELRKLLNFYEKQEGEKLPFLGLALSSRKNLCIHPEVTPLRFGKDVDGKCHSLTASYVRAQYQHD--TSLPHCRFYEEFDAHGREVPLPAGIYNLDDLKALGRRQGWCPYFLARYSILHANVVVYSYHYLLDPKIADLVSKELARKAVVVFDEAHNIDNVCIDSMSVNLTRRTLDRCQGNLETLQKTVLRIKETDEQRLRDEYRRLVEGLREASAARET-DAHLANPVLPDEVLQEAVPGSIRTAEHFLGFLRRLLEYVKWRLRVQHVVQESPPAFLSGLAQRVCIQRKPLRFCAERLRSLLHTLEITDLADFSPLTLLANFATLVSTYAKGFTIIIEPFDDRTPTIANPILHFSCMDASLAIKPVFERFQSVIITSGTLSPLDIYPKILDFHPVTMATFTMTLARVCLCPMIIGRGNDQVAISSKFETREDIAVIRNYGNLLLEMSAVVPDGIVAFFTSYQYMESTVASWYEQGILENIQRNKLLFIETQDGAETSVALEKYQEACENGRGAILLSVARGKVSEGIDFVHHYGRAVIMFGVPYVYTQSRILKARLEYLRDQFQIRENDFLTFDAMRHAAQCVGRAIRGKTDYGLMVFADKRFARGDKRGKLPRWIQEHLTDANLNLTVDEGVQVAKYFLRQMAQPFHREDQLGLSLLSLEQLE-------------SEETLKRIEQIAQQL-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7KVP9-1", "uniprot_id": "Q7KVP9_DROME", "id": "Q7KVP9-1", "name": "General transcription and DNA repair factor IIH helicase subunit XPD", "aln": "------------------------------------MKLSVDGLLVYFPYEYIYPEQYAYMLELKRSLDAKGHCLLEMPSGTGKTATLLSLIVAYMVEHPETVRKLIYCSRTVPEIEKVIAELQNLMVYYERHCPNPPPFTGLVLSSRKNMCIHPEVSKEREGKAVDGKCYGLTASYIRERHEMD--TETPICQYFEGFSLEGKESTLPVGVYSIDDLKEYGRSRNWCPYFLARYAIAHAHIVVYSYHYLLDPKIAQVVSKEMSRESCVVFDEAHNIDNVCIDSMSVKINRRTVERSTNALNHLTKLVQDIREEDTNRLNEEYQRMVQGLKDASVQRDT-DMILANPVLPNDVLTEVVPGNIRNADHFLSFLRRFIEYIKTRLRVHHVVQESPAGFLKDISSKICIERKPLRFCAERLSSLLRTLEISDLTEYGALTLITHFATLVSTYTKGFTIIIEPFDDKTPTVSNPILHFSCLDSSIAMAPVFSRFQTVVITSGTLSPMDMYPKILDFDPVVMSSFTMTLARPCLLPMIVSKGNDQVTISSKFETREDTAVIRNYGQLLVEVAKTVPDGIVCFFTSYLYLESVVASWYDQGIVDTLLRYKLLFIETQDNAETSYALMNYVKACDCGRGAVLLAVARGKVSEGVDFDHHYGRAVLMFGIPYVYTQSRILKARLDYLRDQFQIRENDFLTFDAMRHAAQCVGRALRGKTDYGIMIFADKRFSRHDKRSRLPKWIQEHLVDSFCNLSTEEAVQLARRWLRRMAQPFTREDQLGISLLTLAQLENM-----------EQEKLERQAQGKQGVGGEVQEL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P06839-1", "uniprot_id": "RAD3_YEAST", "id": "P06839-1", "name": "General transcription and DNA repair factor IIH helicase subunit XPD/RAD3", "aln": "------------------------------------MKFYIDDLPVLFPYPKIYPEQYNYMCDIKKTLDVGGNSILEMPSGTGKTVSLLSLTIAYQMHYP-EHRKIIYCSRTMSEIEKALVELENLMDYRTKELGYQEDFRGLGLTSRKNLCLHPEVSKERKGTVVDEKCRRMTNGQAKRKLEEDPEANVELCEYHENLYNIEVEDYLPKGVFSFEKLLKYCEEKTLCPYFIVRRMISLCNIIIYSYHYLLDPKIAERVSNEVSKDSIVIFDEAHNIDNVCIESLSLDLTTDALRRATRGANALDERISEVRKVDSQKLQDEYEKLVQGLHSADILTDQEEPFVETPVLPQDLLTEAIPGNIRRAEHFVSFLKRLIEYLKTRMKVLHVISETPKSFLQHLKQLTFIERKPLRFCSERLSLLVRTLEVTEVEDFTALKDIATFATLISTYEEGFLLIIEPYEIENAAVPNPIMRFTCLDASIAIKPVFERFSSVIITSGTISPLDMYPRMLNFKTVLQKSYAMTLAKKSFLPMIITKGSDQVAISSRFEIRNDPSIVRNYGSMLVEFAKITPDGMVVFFPSYLYMESIVSMWQTMGILDEVWKHKLILVETPDAQETSLALETYRKACSNGRGAILLSVARGKVSEGIDFDHQYGRTVLMIGIPFQYTESRILKARLEFMRENYRIRENDFLSFDAMRHAAQCLGRVLRGKDDYGVMVLADRRFSR--KRSQLPKWIAQGLSDADLNLSTDMAISNTKQFLRTMAQPTDPKDQEGVSVWSYEDLIKHQNSRKDQGGFIENENKEGEQDEDEDEDIEMQ--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **: :*.* * *** *****: ** ::*::**. *: :**********.:**:* :** :* *:******:.****.: **.:*: : :. * ** *:****:*:****: * *. ** ** :* . : : : * :. *.:.* : : ** *::.::.* . : ****:.* * .::::************: **:*:::.: *:************:*:*:.:. :: *. : * : : ::: * ::*.:**.::*:**:.*. : : : .****:::* *.:**.** *:**:.**:*::**:* *::* **:.*:* .**. : . *:*******:*** *::***:::: :: .*. :: ****:*** :** :****:: ...::.**:::*:*:*:*:*: ***.**.:*:*****:**:*:**::*:*..* :::****: .: ***: :*.***:***:** *:* :::****.:*:*.: .***:* **.** *:** *: * **:: : : **:::** * *** ** .* :**. ****:**:*********:** *:***:*:*:*:*: **:********:::*::::*******:**********:**.:*** ***:*::**:**:* **.:**:** : * *: **:.: .:. :: :** **** :** *:*: : :* .:*. : : : ", "identical_positions": 345, "similar_positions": 250, "identity": "42.12%" }, { "cls_id": "homologset.agr.RGD:1309110", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9BZP6-1", "uniprot_id": "CHIA_HUMAN", "id": "Q9BZP6-1", "name": "Acidic mammalian chitinase", "aln": "------------------------MTKLILLTGLVLILNLQLG---------------------------SAYQLTCYFTNWAQYRPGLGRFMPDNIDPCLCTHLIYAFAGR-QNNE---ITTIEWN-----DVTLYQAFNGLKNKNSQ--------------------------LKTLLAIGGWNFGTAPFTAMVSTPENRQTFITSVIKFLRQYEFDGLDFDWEYPGS--RGSPPQDKHLFTVLVQEMREAFEQEAKQINKPRLMVTAAVAAGISNIQSGYEIPQLSQYLDYIHVMTYDLHGSWEGYTGENSPLYKYPTDTG----SNAYLNVDYVMNYWKDNGAPAEKLIVGFPTYGHNFILSNPSNTGIG-----APTSGAGPAGPYAKESGIWAYYEICTFLKN---GATQGWDAPQEVPYAYQGN-------VWVGYDNIKSFDIKAQWLKHNKFGGAMVWAIDLDDFTGTFCNQG-----------------------------------------------------KFPLISTLKKALGLQSASCTAPAQPIEPITAAPSGSGNGSGSSSSGGSSGGSGFCAVRANGLYPVAN-------------------------------NRNAFWHCVNGVTYQQNCQAGLVFDTSCDCCNWA---------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D4A2D4-1", "uniprot_id": "D4A2D4_RAT", "id": "D4A2D4-1", "name": "", "aln": "-------MLYKTSEDPAGSVLRAFISKLVFIMGLNLLLNVQLD---------------------------SAYQLMCYFNNWPQYQPDVRGMKLDDIDPCLCTHLIYSFAGI-WENN---NTMTKRK-----DLDDYKEFNDLKKRNNK--------------------------LKTLLSIGCWNFEAGLFITMVSTPESRHTFITSVRKFLRKYGFDGLNLAWQYPGC--YGSPPKDKHLFTILTQEIRKAFEKEVSKNKKSRLIITAALAGVISPIQFGYHVPQLSQSLDYIQVMTYDLHGSWDGYTGENSPLYKSPAETG----VKAFYNIKYTMHNWKNKGVSPEKLIVGFPAYGHTFILSDSTKTEIG-----APSNRGGHPGPYTKKTGFWAYYEICAFLKN---GAIQVWNAAQQVPYAFHGN-------EWVGYDNVKSFHIKAQWLKNNNFGGAMIWAIGMDDYTGSFCDQG-----------------------------------------------------PFPLTSTLKNALKVHSASCKVTAL-----------SANVTGSRDSN-------FGALEP--LFQLSS-------------------------------K------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VFR3-1", "uniprot_id": "Q9VFR3_DROME", "id": "Q9VFR3-1", "name": "chitinase", "aln": "-------------------MVRYIPLLLLGVLCSWPAATVASD---------------------------QASRIVCYFSNWAVYRTGIGRYGLEDVPADLCTHIIYSFIGV-NDKS---WDVLVIDPELDVDQGGFSKFTQLKKSNPN--------------------------VKLEIAVGGWAEGGSKYSQMVAVRDRRQSFIRSVVRFMKQYNFDGFDLDWEYPGATDRGGNYGDKDKFLYFVEELRRAFDREGR-----GWEITMAVPVAKFRLNEGYHVPELCEALDAIHAMTYDLRGNWAGFADVHSPLYKRKHDQY----AYEKLNVNDGLALWEEMGCPANKLVVGVPFYGRTFTLSNSNKNYNMG-TYINKEAGGGAPGPYTNASGFLAYYEICTEVMDKSKGWTVEWDDAGMVPYTYKDT-------QWVGYENEASIQIKMDFIKQRGYAGAMTWAIDMDDFHGMCGRKNGLTQILYDNMKNYRVPEPTRQTTPRPEWAKPPATPPNPDEGAVVAPTTSTTKRPKPKPKPTSSPLSPTSAPGPVPTVGSSTPKPTTKKPKKPKKTTTTTTTTPAPEKSTEEPEEVVYPVDPVEPTDPEQPMGPQFDPNEIDCTNRDFVPHPNCRKYFRCVHGKPVEFECKEGTAFHTVLNVCDWIENSDRYYCSRMKNKEKGNEAH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W2M6-1", "uniprot_id": "Q9W2M6_DROME", "id": "Q9W2M6-1", "name": "chitinase", "aln": "---------------------MKLVSIWALAALCLCLGQVAS----------------------------SEKLLNCYWGTWANYRPGDGKFTPSDIDPSLCTHISYTFFGI-SDAGEFKSLDTWLDMDD--GLGFISQTIALKQRNPN--------------------------LKILAVVGGWNEGSTKYSAMAADPAKRATFVSTSLAFIQQYSFDGLDLDWEYPGQR-GGSEA-DRENFVTLLREIKETYD-------QYGLELGIAVGASEKSASISYDIPAISQHLTFINVMTYDFHMALDGYLGLNAPLPEVAESID----------------YWLSHGAPAEKLILGIGFYGHSYQMSDSSQNWPG-----AACIGPGTAGVYTRENGFLGYHEICLNN------WQTVFDQENGAPYAFQGD-------QWIGYDNPESIQLKMQLVESRNLGGAMMWSIETDDFRGLCG-ES------------------------------------------------------YPLLKTMNRALGREVSGGSGGGGGGGGEGSVTPAPTAAPTSSPTPAPTPGGGSGGNECAQDGFFVLE-----------------------------SDCNKFYQCVGGVRYDFQCGAGLCFNTITLNCDWP---------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W2M5-1", "uniprot_id": "Q9W2M5_DROME", "id": "Q9W2M5-1", "name": "", "aln": "-----------------------MGKLLALLAV-LCLSQVIG----------------------------AERIVNCYWGTWANYRSGNGKFDVSNIDAGLCTHLSYSFFGI-NDNGEIQSLDTWLDYD----LGFINQAISLKNQNSN--------------------------LKVLAVVGGWNEGSTKYSSMSGDWYKRQNFINSALNLLRNHGFDGLDLDWEYPNQR-GGNWN-DRANFVTLLREIKEAFA-------PYGYELGIAVGAGESLASASYEIANIAQQVDFINVMTYDFAMASDGQTGFNAPQWAVENAIN----------------FWLSQGAPANKLVLGVGTYGRSFQLSDSSQNWPG-----APCRGEGSAGSYTGSTGYLGYNEICQNN------WHTVFDYDNAAPYAYSGD-------QWVSFDNVLSVQYKMDFALSKGLAGAMIWSLETDDYRGQCG-ET------------------------------------------------------YPLLKTINRKLRW-------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W2M7-1", "uniprot_id": "Q9W2M7_DROME", "id": "Q9W2M7-1", "name": "chitinase", "aln": "-----------------MWSVSGLVKLLLGVILMAASSSAQGN---------------------------SSKNVVCYQGTWSVYRPGLGKFGMEDIDPFLCTHLIYAFLGI-EETGQLRVIDAYLDLEENSGRGNIKSFNALKLKNPV--------------------------LKTLVAVGGWNEGSKRFSLVARDPSKREKFVDDVVRFLQRHGFDGLDLDWEYPGQR-HSLDNEDRSNYITFLKELKEGLE-------PFGFILSAAVGSAQFSAEISYDIPAMVPYLDLINVMAYDLHGPWDQVVGINAPLYAAEKDASDSSGRQQQLNVDAVVKYWLKAGAPAEKLILGVPFYGRSFTLATAEGNQPG-----APHIGKGIAGNYSREPGVLGYNELCEMMERE--EWTQKWEATQQVPYAYRQR-------QWVGYEDPRSLALKAQYVMDNHLGGIMIWSLESDDFRGTCGQQP------------------------------------------------------YPLLHEINRVLFG--------------------GNTPSGLTTESNRESPSEGFSCPADAPAGYIRDP-----------------------------DNCSKFYYCSGGKTHNFDCPSGLNFDLDTKSCNYSGSVKC----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W092-1", "uniprot_id": "CHIT2_DROME", "id": "Q9W092-1", "name": "Probable chitinase 2", "aln": "-----MTLRSRLSGEAPQLWLLLLLASTASSLWASVAARTGPL---------------------------HDKVVVCYVSTWAVYRPEQGAYAIENFDPNLCTHVVYAFAGLDITQAAIKSLDPWQDLKEEYGKGGYEKMTGLKRSHPH--------------------------LKVSLAIGGWNEGSANYSTLVANNLLRGRFVKQVSSFIRKYNFDGLDLDWEYPTQR--KGKPADRENFVLLTKELREEFD-------EHGLLLTSAIGASKKVIDEAYDVRQISRYLDYLHIMCYDYHGSWDRRVGYNAPLTAPADDPLS---------VKFSIDYLLKLGAPPEKLVMGLPFYGRTFKTLASG--FLN-----DVSEGVGFKGPYTREDGFLGYNEICQTLSNQTSGWTREWDPQTSQVLAKSERNVFTQEINVVTYDSSRSIANKVLFAMSKRLAGVMVWSVDTDDFLGNCKLDED----------------------------------------------------TYEDFQKVTAAPKRSSQNYPLLRT----------INEATMLAVDELAVPEPQPDDSENEIPHGSIADR------------------------------------KNAGASMVSLGLGVTAVFMLLHRLAQ-----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06350-1", "uniprot_id": "CHI2_YEAST", "id": "Q06350-1", "name": "Sporulation-specific chitinase 2", "aln": "MVGHSAQHRSKSSLVSHLLILLIFITIIIEMCLYNKIFKNQRSDDIRDNFNNGGHRVPSNVQNHGTHIRDEAFISGVYYSNWSPYKP--RFHFPHDINLKQVSHIYYAFFKINSRTGGIENTDSWSDLEMNLYKSLAIKNSELIKESSNNSVQNILPLGCIGELFYLKNTCSDKKFKVIMSIGGWSD-SENFKIIIKDDKLLQNFVDSSVETMFRLGFDGIDLDWEFPGNN--ESEPRGYLKLVRMLRLKLNSLESQIFGKRTEDHFQLSIAAPAFKDKLFYLPITEIDQYVDYWNMMTYDYYGSWSETTGYHSNLFSETELNGN----------FAMHYMIDRFGVNSRKLVLGMAAYGRSFHIKDNKFEPFNQNTVLINKIFKGVGKPTKEIDKADGKEGIWPYKNLPKIGTIEQYDPKYVSAYCFDEKNS-----IFISYDNTKSVKTKAEYVTHNNLGGGFWWESCGEAYANESR----------------------------------------------------------SLINAFNEGLHFNVSSKPS-------------IFQDVRVKKYYLNKYGDGGFLSPYLKHLDSRKQ--------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .*. *:. :. :*: *:* . * .* :* * : : *: : . ***::: *::* . : . . : : : : * ** . :: * ..**::*. **:.: * . : :: : ::. *. * . .* : * : : . . ", "identical_positions": 30, "similar_positions": 57, "identity": "4.36%" }, { "cls_id": "homologset.agr.RGD:1309111", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "B4F766-1", "uniprot_id": "DYM_RAT", "id": "B4F766-1", "name": "Dymeclin", "aln": "MGSNSSKISDLPKNEYLKRLSGPEAIS-ENDPFWNQLFSFSFSAPTSSTELKLLEEATISVCKSLVENNPRTGNLAALTKVFLARTRELRLSAECQNHIFIWQTHNALFIICCLLKVFICEMSEEELQLHFTYE-------------EKLPGTYTLCVLLGSDSED-----------LLEELLCSLIQLITDTPLLDITYEISVEAISAMIVFLSCQLFHKEVLRQSISHKYLMQGPCLPYTSKLVKTLLYNFIRQEKPPPPGTHVFPQQSDGGGLLYGLASGVATGLWTVFTLG--GVGSKAAS-PELTS------PLANQSLLLLLVLVNLTDAPDIPNPYRQAVTSFKNTQDSSPFPSSVPHTFQINFNSLYTTLCEQQTSDQATLLLYTLLHQNANVRTYMLARTDMENLVLPILEILYHVEERNSHHVYMALIILLILTEDDGFNRSIHEVILKNITWYSERVLTEISLGSLLILVVIRTIQYNMTRTRDKYLHTNCLAALANMSAQFRSLHQYAAQRIISLFSLLSKKHNKVLEQATQSLR-GSLSSSDVPLPDYAQDLSVIEEVIRMMLEIINSCLTNSLHHNPNLVYALLYKRDLFEQFRTHPSFQDIMQNIDLVISFFSSRLLQSG---AELSVERVLEIIKQGVVALPKDRLKKFPELKFKYVEEEQPEEFFIPYVWSLVYNSAVGLYWNPQDIQLFAMDSD-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CHY3-1", "uniprot_id": "DYM_MOUSE", "id": "Q8CHY3-1", "name": "Dymeclin", "aln": "MGSNSSKISDLPKNEYLKKLSGPESIS-ENDPFWNQLFSFSFPAPTSSSELKLLEEATISVCKSLVENNPRTGNLAALTKVFLSRTRELRLSAECQNHIFIWQTHNALFIICCLLKVFIRELSEEELQLHFTYE-------------EKSPGSYS------SDSED-----------LLEELLCSLVQLITDTPLLDITYEIAVEAISAMVVFLSCQLFHKEVLRQSISHKYLMQGPCLPYTSKLVKTLLYNFIRQEKPPPPGTHVFPQQSDGGGLLYGLASGVATGLWTVFTLG--GAGSKAAASPELTS------PLANQSLLLLLVLVNLTDAPDIPNPYRQAVSSFKNTQDSSPFPSSIPHTFQINFNSLYTALCEQQTSDQATLLLYTLLHQNSNVRTYVLARTDMENLVLPILEILYHVEERNSHHVYMALIILLILTEDDGFNRSIHEVILRNITWYSERVLTEISLGSLLILVVIRTIQYNMTRTRDKYLHTNCLAALANMSAQFRSLHQYAAQRIISLFSLLSKKHNKVLEQATQSLR-GPLSSSDVPLPDYAQDLSVIEEVIRMMLEIINSCLTNSLHHNPNLVYALLYKRDLFEQFRTHPSFQDIMQNIDLVISFFSSRLLQAG---AELSVERVLEIIKQGVVALPKDRLKKFPELKFKYVEEEQPEEFFIPYVWSLVYNSAVGLYWNPQDIQLFAMDSD-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7RTS9-1", "uniprot_id": "DYM_HUMAN", "id": "Q7RTS9-1", "name": "Dymeclin", "aln": "MGSNSSRIGDLPKNEYLKKLSGTESIS-ENDPFWNQLLSFSFPAPTSSSELKLLEEATISVCRSLVENNPRTGNLGALIKVFLSRTKELKLSAECQNHIFIWQTHNALFIICCLLKVFICQMSEEELQLHFTYE-------------EKSPGNYS------SDSED-----------LLEELLCCLMQLITDIPLLDITYEISVEAISTMVVFLSCQLFHKEVLRQSISHKYLMRGPCLPYTSKLVKTLLYNFIRQEKPPPPGAHVFPQQSDGGGLLYGLASGVATGLWTVFTLG--GVGSKAAASPELSS------PLANQSLLLLLVLANLTDASDAPNPYRQAIMSFKNTQDSSPFPSSIPHAFQINFNSLYTALCEQQTSDQATLLLYTLLHQNSNIRTYMLARTDMENLVLPILEILYHVEERNSHHVYMALIILLILTEDDGFNRSIHEVILKNITWYSERVLTEISLGSLLILVVIRTIQYNMTRTRDKYLHTNCLAALANMSAQFRSLHQYAAQRIISLFSLLSKKHNKVLEQATQSLR-GSLSSNDVPLPDYAQDLNVIEEVIRMMLEIINSCLTNSLHHNPNLVYALLYKRDLFEQFRTHPSFQDIMQNIDLVISFFSSRLLQAG---AELSVERVLEIIKQGVVALPKDRLKKFPELKFKYVEEEQPEEFFIPYVWSLVYNSAVGLYWNPQDIQLFTMDSD-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7KNA0-1", "uniprot_id": "DYM_DROME", "id": "Q7KNA0-1", "name": "Dymeclin", "aln": "MGINVSRTADLGSNQWLQRFVGRQHIAHDDEAFWNGLLNYNIVLPENSQDQLNLDSRLEALCQSFIGNNLKTGNFGSLVTVFLEKTSELLSLSDQESNMHVWQTFNALFIIRSLVKYINETGSEFQLLQHFEAMPNAELLQAALEQQQQTPAESATIAMEATEQSAAAAVPVIVDGSKFETFIDALVNLIVVIPVKEFTYHLHLEAVNMLITLLSVHLFAQQPTDKSIVFRTVFK---CQHANVLMSALLHFVARIVEVP----HTMFGSSSAGSFVFGIAESLLS-IFTFRKQPDILKAGQAAGGGELSQRFRTHYPLANQSLLLILILTNHCTAQD--NAYRTSLFSCADSKDS---PKQGAVSFQIDFSAVYETLCTIVTIDQATLLLYLLLHRNERFYRFVMQQQDLEQLVIPILQTLYNAPDSNSHHIYMSLIVLLILSEDEGFNKNVHTIMLKNITWYTERTISEISLGGILILIVIRTIQYNMLKMRDKYLHTNCLAALANMSGHFRALHPYVAQRLVSLFETLARKHTRLDAQLKEPADSAVFVNVSTTPEDMLQDLSVLEEVLRMVLEILNSCLTNQLVYCPNLVYTLLYKRSVFEGFRSHHAFQDVIQNIDMVVGFFSSRLQRVQEQRGELGVNEVLEVISKGASQWSSDRLRKFPDLKFKYVEEDAPEEFFIPYVWTLVCKYGC-VHFSSESIKSVTTDIAC", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** * *: .** .*::*::: * : *: :::.*** *:.:.: * .* : *:. ::*:*:: ** :***:.:* .*** :* ** :: :.::.:***.****** .*:* : ** :* ** :: *. : ::.. :* :: .*::**. *: ::**.: :**:. ::.:** :** :: :** .: ::: ::. *:.:**: . * : * *.: .*..*.:::*:*..: : ::*. . ..:**. **:. *********:*:*.* * * *.** :: * :::** *.. . :***:*.::* :** * ******** ***:* .. ::: : *:*:**:***: **:. : ****:**:**:****:**:***:.:* ::*:*****:**.::*****.:***:********* : *****************.:**:** *.***::***. *::**.:: * .:. . : . ... * ***.*:***:**:***:******.* : *****:*****.:** **:* :***::****:*:.****** : .**.*:.***:*.:*. ..***:***:********: **********:** : . :::..:.*: .: * ", "identical_positions": 288, "similar_positions": 232, "identity": "40.39%" }, { "cls_id": "homologset.agr.RGD:1309112", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P35290-1", "uniprot_id": "RAB24_MOUSE", "id": "P35290-1", "name": "Ras-related protein Rab-24", "aln": "MSGQRVDVKVVMLGKEYVGKTSLVERYVHDRFLVGPYQNTIGAAFVAKVMCVGDRTVTLGIWDTAGSERYEAMSRIYYRGAKAAIVCYDLTDSSSFERAKFWVKELRSLEEGCQIYLCGTKSDLLEEDRRRRRVDFHDVQDYADNIKAQLFETSSKTGQSVDELFQKVAEDYVSVAAFQVMTEDKG--------VDLSQKAN-------------PYFYSCCHH------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q969Q5-1", "uniprot_id": "RAB24_HUMAN", "id": "Q969Q5-1", "name": "Ras-related protein Rab-24", "aln": "MSGQRVDVKVVMLGKEYVGKTSLVERYVHDRFLVGPYQNTIGAAFVAKVMSVGDRTVTLGIWDTAGSERYEAMSRIYYRGAKAAIVCYDLTDSSSFERAKFWVKELRSLEEGCQIYLCGTKSDLLEEDRRRRRVDFHDVQDYADNIKAQLFETSSKTGQSVDELFQKVAEDYVSVAAFQVMTEDKG--------VDLGQKPN-------------PYFYSCCHH------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A096MKB0-1", "uniprot_id": "A0A096MKB0_RAT", "id": "A0A096MKB0-1", "name": "Ras-related protein Rab-24", "aln": "MSGQRVDVKVVMLGKEYVGKTSLVERYVHDRFLVGPYQNTIGAAFVAKVMCVGDRTVTLGIWDTAGSERYEAMSRIYYRGAKAAIVCYDLTDSSSFERAKFWVKELRSLEEGCQIYLCGTKSDLLEEDRRRRRVDFHDVQDYADNIKAQLFETSSKTGQSVDELFQKVAEDYVSVAAFQVMTAVVTTESQLICPVELDELPEGLDPTLVWAGVVKRLSYSRCPLQQRWHLPVLARGTEAVLG", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**************************************************.*********************************************************************************************************************************** *:*.: .: ** * ", "identical_positions": 186, "similar_positions": 6, "identity": "76.86%" }, { "cls_id": "homologset.agr.RGD:1309113", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZWL5-1", "uniprot_id": "D3ZWL5_RAT", "id": "D3ZWL5-1", "name": "", "aln": "------MEP--------GNYATLDGAKDIEGLLGAG-----GGRNLVAHSSPLASHPAAPTLMPTVNYAPLDLPGSAEPPKQCHPCPGVPQGASPAPVPYGYFGGGYYSCRVSRSSLKPCAQTATLATYPS---ETPAPGEEYPSRPTEFAFYPGYPGPYQPMASYLDVSVVQTLGAPGEPRHDSLLPVDSYQPWALAGGWNSQMCCQGEQNPPGPFWKAAFAEPSVQHPPPDGCAFRRGRKKRIPYSKGQLRELEREYAANKFITKDKRRKISAATSLSERQITIWFQNRRVKEKKVLAKVKTSTTP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70321-1", "uniprot_id": "HXB13_MOUSE", "id": "P70321-1", "name": "Homeobox protein Hox-B13", "aln": "------MEP--------GNYATLDGAKDIEGLLGAG-----GGRNLVSHSSPLASHPAAPTLMPTVNYAPLDLPGSAEPPKQCHPCPGVPQGASPAPVPYGYFGGGYYSCRVSRSSLKPCAQTAALATYPS---ETPAPGEEYPSRPTEFAFYPGYPGPYQPMASYLDVSVVQTLGAPGEPRHDSLLPVDSYQPWALAGGWNSQMCCQGEQNPPGPFWKAAFAEPSVQHPPPDGCAFRRGRKKRIPYSKGQLRELEREYAANKFITKDKRRKISAATSLSERQITIWFQNRRVKEKKVLAKVKTSTTP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92826-1", "uniprot_id": "HXB13_HUMAN", "id": "Q92826-1", "name": "Homeobox protein Hox-B13", "aln": "------MEP--------GNYATLDGAKDIEGLLGAG-----GGRNLVAHS-PLTSHPAAPTLMPAVNYAPLDLPGSAEPPKQCHPCPGVPQGTSPAPVPYGYFGGGYYSCRVSRSSLKPCAQAATLAAYPA---ETPTAGEEYPSRPTEFAFYPGYPGTYQPMASYLDVSVVQTLGAPGEPRHDSLLPVDSYQSWALAGGWNSQMCCQGEQNPPGPFWKAAFADSSGQHPP-DACAFRRGRKKRIPYSKGQLRELEREYAANKFITKDKRRKISAATSLSERQITIWFQNRRVKEKKVLAKVKNSATP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1ECY2-1", "uniprot_id": "HXBDA_DANRE", "id": "Q1ECY2-1", "name": "Homeobox protein Hox-B13a", "aln": "MTTSLVLNPRWADTVMFVYENNLDELKNMEGLVGSGNFAANQCRNLMAHS-ALSGHPSSLVHGSSYPTVDVSTSSSAESGKQCTPCPTVPQASSTGPIPYGYFGNSYYPCRMGRGSLKSCTQPSALSYTAEKYMDTPVTSEEYPTRAKEFAFYHSYPSPYQSMASYLDVSVVQTLGT-GEPRHDSLLPMDSYQPWALANGWGSQMYCSKDQGQAGHLWKSALAD-VVAHQH-DGGSFRRGRKKRIPYTKVQLKELEKEYAANKFITKDKRRKISAVTNLSERQITIWFQNRRVKEKKFIAKVKNTAP-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::* .** *::***:*:* ***::** .*:.**:: . .: . :. ..***. *** *** ***.:*..*:******..**.**:.*.***.*:*.::*: . :**...****:*..***** .**..**.**************: **********:****.****.**.*** *. :*. .* :**:*:*: * *. :***********:* **:***:******************.*.*******************.:****.::. ", "identical_positions": 169, "similar_positions": 78, "identity": "54.87%" }, { "cls_id": "homologset.agr.RGD:1309114", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6B3M3-1", "uniprot_id": "A0A8I6B3M3_RAT", "id": "A0A8I6B3M3-1", "name": "", "aln": "MVGLGACNLTGVTLIVLLLPRSLEGCGQIRISPPIVHLGDPVLASCTISPNCSKLDRQPKILWRLQDEPNQPGDRQHHLPDGSQESIITLPHLNYTQAFLFCLVPWNNSFQVLDQAELRAGYPPASPSNLSCLMYLTTNSLVCQWEPGPETHLPTSFILKSFRSRTGCQYQGGTILDCMPKKRHSNCSIPRKHLLLYQNMVIWVQAENMLGSSESPKLCIDPMDVGRESLTTPPPAVKLEPPMLQALDIGHDIVSRQPGCLWLSWKPWKPSEFMEQECELRYQPQLEGANWTLVRPRKTSRWRWGMERGQAGFSVTPPTHQVSHLPSSTDRFELCSLHQAPVYTLQLRCIRSSLPGLWSSWSPGLQLRPTIKAPTIRLDTWWQKKHLDPETVRMQLFWKPTPLQKDSGQIQGYLLSWSCPDGQGRIMHLCNTTELSCTFHLPSEAQNVTLVAYNSAGTSSPTLVVFLEHEGPAVTSLHAMAQDLGSIWVDWEAPSLLPQGYLIEWGPDSHKYSN--NSWRIEPNGNTTGILLEDNIHPFQLYRITVAPLYPGTVGPPVNVYTYSGEKALPHAPELYLKHVGRTWAQLEWVPETPWLGMIPLTNYTIFWTDARDHSFSVTLNISFHDFVLDHLKPASLYHVYLMATSRAGSTNSTGLTLMTMALDSSDVNIFLGIL-CFVLLSITCATAWFCCKQSRKTFFWPNVPDPAHSSLSAWVPTIMTEETFQLPSFWGSSVPSITKITELEED-KKPTHWDPSESSGTGSLPAVVQAYVLQGDPREISNQFQPPSSTNDQVLYGQVLGSPTSPEVVGYLRCDSTQPLLGGPTPSPKSYENIWFHSRPQETFIPQPPSQEDDCVFGPPFDFPLFQGLQVHGVEEQGGF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P40223-1", "uniprot_id": "CSF3R_MOUSE", "id": "P40223-1", "name": "Granulocyte colony-stimulating factor receptor", "aln": "MVGLGACTLTGVTLIFLLLPRSLESCGHIEISPPVVRLGDPVLASCTISPNCSKLDQQAKILWRLQDEPIQPGDRQHHLPDGTQESLITLPHLNYTQAFLFCLVPWEDSVQLLDQAELHAGYPPASPSNLSCLMHLTTNSLVCQWEPGPETHLPTSFILKSFRSRADCQYQGDTIPDCVAKKRQNNCSIPRKNLLLYQYMAIWVQAENMLGSSESPKLCLDPMDV-----------VKLEPPMLQALDIGPDVVSHQPGCLWLSWKPWKPSEYMEQECELRYQPQLKGANWTLV----------------------------FHLPSSKDQFELCGLHQAPVYTLQMRCIRSSLPGFWSPWSPGLQLRPTMKAPTIRLDTWCQKKQLDPGTVSVQLFWKPTPLQEDSGQIQGYLLSWSSPDHQGQDIHLCNTTQLSCIFLLPSEAQNVTLVAYNKAGTSSPTTVVFLENEGPAVTGLHAMAQDLNTIWVDWEAPSLLPQGYLIEWEMSSPSYNNSYKSWMIEPNGNITGILLKDNINPFQLYRITVAPLYPGIVGPPVNVYTFAGERAPPHAPALHLKHVGTTWAQLEWVPEAPRLGMIPLTHYTIFWADAGDHSFSVTLNISLHDFVLKHLEPASLYHVYLMATSRAGSTNSTGLTLR--TLDPSDLNIFLGIL-CLVLLSTTCVVTWLCCKRRGKTSFWSDVPDPAHSSLSSWLPTIMTEETFQLPSFWDSSVPSITKITELEED-KKPTHWD-SESSGNGSLPALVQAYVLQGDPREISNQSQPPSRTGDQVLYGQVLESPTSPGVMQYIRSDSTQPLLGGPTPSPKSYENIWFHSRPQETFVPQPPNQEDDCVFGPPFDFPLFQGLQVHGVEEQGGF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99062-1", "uniprot_id": "CSF3R_HUMAN", "id": "Q99062-1", "name": "Granulocyte colony-stimulating factor receptor", "aln": "MARLGNCSLTWAALIILLLPGSLEECGHISVSAPIVHLGDPITASCIIKQNCSHLDPEPQILWRLG-AELQPGGRQQRLSDGTQESIITLPHLNHTQAFLSCCLNWGNSLQILDQVELRAGYPPAIPHNLSCLMNLTTSSLICQWEPGPETHLPTSFTLKSFKSRGNCQTQGDSILDCVPKDGQSHCCIPRKHLLLYQNMGIWVQAENALGTSMSPQLCLDPMDV-----------VKLEPPMLRTMDPSPEAAPPQAGCLQLCWEPWQPGLHINQKCELRHKPQRGEASWALVG----------------------------PLPLEALQYELCGLLPATAYTLQIRCIRWPLPGHWSDWSPSLELRTTERAPTVRLDTWWRQRQLDPRTV--QLFWKPVPLEEDSGRIQGYVVSWRPSGQAGAILPLCNTTELSCTFHLPSEAQEVALVAYNSAGTSRPTPVVFSESRGPALTRLHAMARDPHSLWVGWEPPNPWPQGYVIEWGLGPPSASNSNKTWRMEQNGRATGFLLKENIRPFQLYEIIVTPLYQDTMGPSQHVYAYSQEMAPSHAPELHLKHIGKTWAQLEWVPEPPELGKSPLTHYTIFWTNAQNQSFSAILNASSRGFVLHGLEPASLYHIHLMAASQAGATNSTVLTLMTLTPEGSELHIILGLFGLLLLLTCLCGTAWLCCSPNRKNPLWPSVPDPAHSSLGSWVPTIMEEDAFQLP---GLGTPPITKLTVLEEDEKKPVPWESHNSSETCGLPTLVQTYVLQGDPRAVSTQPQSQSGTSDQVLYGQLLGSPTSPGPGHYLRCDSTQPLLAGLTPSPKSYENLWFQASPLGTLVTPAPSQEDDCVFGPLLNFPLLQGIRVHGMEALGSF", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. ** *.** .:**.**** *** **:* :*.*:*:****: *** *. ***:** :.:***** ***.**::*.**:***:*******:***** * : * :*.*:***.**:****** * ****** ***.**:*************** ****:** .** **.:* **:.*. :.:*.****:***** * ******* **:* **:**:***** ********:::* . : .. *.*** *.*:**:*. .::*:****::** *.*:** ** . ::***.* *..****:**** .*** ** ***.*:**.* :***:***** ::::*** ** ******.**::***:****::** .. * : *****:*** * ******:*:*****.**** ** *** * .***:* *****:* ::**.**.*. ****:*** .. . .* ::* :* **. **:**::**.*****.* *:*** . :**. :**::: * * .*** *:***:* **********.* ** ***:*****::* ::***. ** * :.***. *:******::***:*:**:**** *** : : *:::*:**:: ::**: * .:*:**. *. :*..*********.:*:**** *::**** . ..*.***:* **** ***. *: :** . .**::**:******** :*.* *. * *.*******:* ***** *:*.*******.* *********:**:: * *::. .*.********* ::***:**::***:* *.*", "identical_positions": 494, "similar_positions": 205, "identity": "56.07%" }, { "cls_id": "homologset.agr.RGD:1309115", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5PQJ6-1", "uniprot_id": "P5CR3_RAT", "id": "Q5PQJ6-1", "name": "Pyrroline-5-carboxylate reductase 3", "aln": "----MADEMSEPR----------RVGFVGAGRMAEAIAQGLIRAGKVEAKQVLASAPTDK--NLCHFRALG-----CQTTHSNHEVLQNCPLVIFATKPQVLP-----AVLAEVAPVVTTEHIIVSVAAGISLSSMEELLP----PKTRVLRVSPNLPCVVQEGAMVMTRGHHAGNEDAKLLQNLLEACGQCIEVPESYVDIHTGLSGSGVAFVCTFSEALAEGAIKMGMPSDLAHRIAAQTLLGTAKMLQQEGKHPAQLRTDVLTPAGTTIHGLHALEQGGFRAAAMSAVEAATCRAKELSKK----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DCC4-1", "uniprot_id": "P5CR3_MOUSE", "id": "Q9DCC4-1", "name": "Pyrroline-5-carboxylate reductase 3", "aln": "----MAATMSEPR----------RVGFVGAGRMAEAIARGLIQAGKVEAKQVLASAPTDN--NLCHFRALG-----CQTTHSNHEVLQNCPLVIFATKPQVLP-----TVLAEVAPIVTTEHIIVSVAAGISLSTMEGLLP----PNTRVLRVSPNLPCVVQEGAMVMARGHHAGNDDAELLQNLLEACGQCIEVPESYVDIHTGLSGSGVAFVCTFSEALAEGAIKMGMPSGLAHRIAAQTLLGTAKMLQQEGKHPAQLRTDVLTPAGTTIHGLHALERGGFRAATMSAVEAATCRAKELSKK----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q53H96-1", "uniprot_id": "P5CR3_HUMAN", "id": "Q53H96-1", "name": "Pyrroline-5-carboxylate reductase 3", "aln": "----MAAAEPSPR----------RVGFVGAGRMAGAIAQGLIRAGKVEAQHILASAPTDR--NLCHFQALG-----CRTTHSNQEVLQSCLLVIFATKPHVLP-----AVLAEVAPVVTTEHILVSVAAGVSLSTLEELLP----PNTRVLRVLPNLPCVVQEGAIVMARGRHVGSSETKLLQHLLEACGRCEEVPEAYVDIHTGLSGSGVAFVCAFSEALAEGAVKMGMPSSLAHRIAAQTLLGTAKMLLHEGQHPAQLRSDVCTPGGTTIYGLHALEQGGLRAATMSAVEAATCRAKELSRK----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5SPD7-1", "uniprot_id": "P5CR3_DANRE", "id": "Q5SPD7-1", "name": "Pyrroline-5-carboxylate reductase 3", "aln": "----MSLSGASDKTSDSPDVFQIKIGFIGAGNMAFGVAQGIIASGKVPPSNIIISAPSMN--NLPRFKEKG-----VSVTHSNHEVVGGSRLIFLAVKPHIIP-----QVLKEISQEVTKEHIIVSMAAGITIATLEELLP----AGTHVIRIMPNLPCMLLEGALLLSCGSHAGEQEETLLKTLLGPCGLVEFGPESWIDAHVGLSGSGVAFVYVFAEALADGAVKMGMPSTLARRIAAQTILGAGVLLRDSGKLPAELKAEVCTPGGTTIHGIHALEKGGFRAAAIGAVEAASERARELGNKQKKN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VEJ3-1", "uniprot_id": "Q9VEJ3_DROME", "id": "Q9VEJ3-1", "name": "Pyrroline-5-carboxylate reductase", "aln": "----MSAIG--------------KIGFLGGGNMAKALAKGFLAAGLAKPNTLIASVHPADKLSLQSFQSLG-----VETVIKNAPVVQQSDVVFVSVKPQVVP-----SVLSEIQP-LSSGKLFLSVAMGITLSTIESSLS----PQARVIRVMPNLPAVVCSGCSVFVRGSKATDADADITQKLLQSVGTCEPVDESQLDVVTALSGSGPAYVFVMIEALADGAVHMGMPRDLAYRLASQTVLGAGHMVRDSGMHPGQLKDGVTSPAGSTAAALRQLELSGFRAAVSGAVEQATLRCRQISGKTK--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V3F8-1", "uniprot_id": "Q9V3F8_DROME", "id": "Q9V3F8-1", "name": "Pyrroline-5-carboxylate reductase", "aln": "----MAKLD-------------EKIGFIGGGNMAYAIGSGLVRCGIVKASQVQVSGPHIE--NLQRWRDLG-----AVTCDDNCMVLEHSDIVFICVKPHMLTPCAAQLKYKHVPSAKDASKLVVSVLAGTSLETLEEAFSFMGSSELKVIRTMPNTSMQVGEGCTVYTGNARVSHHDLEKIHLMLNALGLAQQVPESMIDAVTGVAGCGPAFVYTIIEALADGGVKQGVPRQMALQFAAQTLLGAAKTVLLTGKHPAVLRDEVCSPGGATIVGVHELEKGNLRSTLINAVEKSSQRSAELGKK----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32263-1", "uniprot_id": "P5CR_YEAST", "id": "P32263-1", "name": "Pyrroline-5-carboxylate reductase", "aln": "MTYTLAILGCGVMG------QALLSAIYNAPKAADETAAAFYPSKIITCNHDEPSAQQVT-DLVETFDESPNGIKVESTYGHNVSAVEEASVVLLGTKPFLAE-----EVLNGVKS-VIGGKLLISLAAGWTIDQLSQYTS-------TVCRVMTNTPAKYGYGCAVVSYSADVSKEQKPLVNELISQVGKYVELPEKNMDAATALVGSGPAFVLLMLESLMESGLKLGIPLQESKECAMKVLEGTVKMVEKSGAHPSVLKHQVCTPGGTTIAGLCVMEEKGVKSGIINGVEEAARVASQLGQKKK--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: .: .. . * . .: . . * : : . * .: . :::. .** : : ::.:*: * :: :. . * * .* . *. : . . : : :: * * :* ..: *.* *:* : *:* :..:: *:* : . * :.: *: : * *. *: * :*.*:* .: :* ..:: ..** :: . ::. * ", "identical_positions": 35, "similar_positions": 86, "identity": "11.36%" }, { "cls_id": "homologset.agr.RGD:1309116", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L579-1", "uniprot_id": "A0ABK0L579_RAT", "id": "A0ABK0L579-1", "name": "Small ribosomal subunit protein uS2m", "aln": "MELLGPCPRRQYPLPSGLPLWPPLLAVAPDPSKGNPFRICKCWRRGLGGTLAQTATARRRRSERCTAGVGPPSQQAALRPRALDPGGALPGRKSLCGISVHAPTMAPAPAVLTRLQCAGLR---RWPGFLQKAAPGPAGQNGRKVTGAPVPAVSEPQD---GDDFQSRILDVPLQHSDFFN--VKELFSVKSLFEARVHLGHKAGCRHRFMEPYIFGNRLGQDIIDLDQTALNLQLALNFTAHVAYRKGIILFVS-RNRQFSHLIETTAQACGEYAHTRYFKGGLLTNAQLL------------------FGPTVRLPDLIVFLHTLNNVFESHVAVRDAAKMNIPTVGIVDTNCNPCLITYPIPGNDDSPQAIQLFCKLFRTTINRAKEKRRQMEALHRLQSPK--GSEGTGTASAPDQSHSP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q924T2-1", "uniprot_id": "RT02_MOUSE", "id": "Q924T2-1", "name": "Small ribosomal subunit protein uS2m", "aln": "--------------------------------------------------------------------------------------------------------MAPAPAVLTRLLCAGVR---RWPGFLQKAIPGPAEQNGRKVTGAPVPAVSEPQD---GDDFQSRILDTPLQHSDFFN--VKELFSVKSLFEARVHLGHKAGCRHRFMEPYIFGNRLGQDIIDLDQTALNLQLALNFTAHVAYRKGIILFVS-RNRQFSHLIETTAQACGEYAHTRYFKGGLLTNAQLL------------------FGPSVRLPDLIIFLHTLNNVFEPHVAVRDAAKMNIPTVGIVDTNCNPCLITYPIPGNDDSPQAIQLFCKLFRTTINRAKEKRRQMEALHRLQSPK--GSEGSGTSPVPDKSHSP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y399-1", "uniprot_id": "RT02_HUMAN", "id": "Q9Y399-1", "name": "Small ribosomal subunit protein uS2m", "aln": "--------------------------------------------------------------------------------------------------------MATSSAALPRILGAGARAPSRWLGFLGKATPRPARPSRRTLGSATALMIRESED---STDFNDKILNEPLKHSDFFN--VKELFSVRSLFDARVHLGHKAGCRHRFMEPYIFGSRLDHDIIDLEQTATHLQLALNFTAHMAYRKGIILFIS-RNRQFSYLIENMARDCGEYAHTRYFRGGMLTNARLL------------------FGPTVRLPDLIIFLHTLNNIFEPHVAVRDAAKMNIPTVGIVDTNCNPCLITYPVPGNDDSPLAVHLYCRLFQTAITRAKEKRQQVEALYRLQGQKEPGDQGPAHPPGADMSHSL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P32902-1", "uniprot_id": "RT04_YEAST", "id": "P32902-1", "name": "Small ribosomal subunit protein uS2m", "aln": "-----MQRHVFARNFRRLSLLRNPSLTKRFQSSASGAANTPNNNDEVMLLQQKLLYDEIRSELKSLSQVPEDEILPELKKSLEQDKLSDKEQQLEAELSDFFRNYALLNKLFDSKTLDGQSSTTTAAATPTKPYPNLIPSANDKPYSSQELFLRQLNHSMRTAKLGATISKVYYPHKDIFYPPLPENITVESLMSAGVHLGQSTSLWRSSTQSYIYGEYKGIHIIDLNQTLSYLKRAAKVVEGVSESGGIILFLGTRQGQKRGLEEAAKKTHGYYVSTRWIPGTLTNSTEISGIWEKQEIDSNDNPTERALSPNETSKQVKPDLLVVLNPTENRNALLEAIKSRVPTIAIIDTDSEPSLVTYPIPGNDDSLRSVNFLLGVLARAGQRGLQNR-----LARNNEK--------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : * . *. * . .: : : :. .: * . *.*:* : * ::*.**:.* ****:.:. : :.**:*. . .****:** *: * :.. :: *****:. *: * * * : * *. **:: * : ..:.: :.*. :: * .: * * : *: :* * .:**:.*:**:.:*.*:***:****** :::: :: : *. ::* * * : ", "identical_positions": 69, "similar_positions": 84, "identity": "16.27%" }, { "cls_id": "homologset.agr.RGD:1309117", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6G3N4-1", "uniprot_id": "A0A8I6G3N4_RAT", "id": "A0A8I6G3N4-1", "name": "small monomeric GTPase", "aln": "MTYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMVNIDGKQIKLQIWDTNSEPEPSYLQAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTSWLEDARQHSSSNMVIMLIGNKSDLESRRDVKREEGEAFAREHGLIFMETSAKTACNVEEAYINTAKEIHRKIQQGLFDVHNEANGIKIGPQQSIS-LVGPCPSQQNSSDIGPDSGCC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P59279-1", "uniprot_id": "RAB2B_MOUSE", "id": "P59279-1", "name": "Ras-related protein Rab-2B", "aln": "MTYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMVNIDGKQIKLQIWDT----------AGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTSWLEDARQHSSSNMVIMLIGNKSDLESRRDVKREEGEAFAREHGLIFMETSAKTACNVEEAYINTAKEIYRKIQQGLFDVHNEANGIKIGPQQSITSSVGPCSPQQNVSDIGPDSGCC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WUD1-1", "uniprot_id": "RAB2B_HUMAN", "id": "Q8WUD1-1", "name": "Ras-related protein Rab-2B", "aln": "MTYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMVNIDGKQIKLQIWDT----------AGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTSWLEDARQHSSSNMVIMLIGNKSDLESRRDVKREEGEAFAREHGLIFMETSAKTACNVEEAFINTAKEIYRKIQQGLFDVHNEANGIKIGPQQSISTSVGPSASQRNSRDIGSNSGCC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O18333-1", "uniprot_id": "RAB2_DROME", "id": "O18333-1", "name": "Ras-related protein Rab-2", "aln": "MSYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDT----------AGQEAFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSNSNMVIMLIGNKSDLDSRREVKKEEGEAFAREHGLVFMETSARTAANVEEAFINTAKEIYEKIQEGVFDINNEANGIKIGQQHSPT---NPSLPGAGGAAGAANSGCC", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:*********************************************:.************* ****:*******************************:*********.**************:***:**:************:******:**.*****:*******:.***:*:**::********* *:* : .*. . . ..:****", "identical_positions": 176, "similar_positions": 28, "identity": "77.88%" }, { "cls_id": "homologset.agr.RGD:1309120", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q641Z5-1", "uniprot_id": "CHAC2_RAT", "id": "Q641Z5-1", "name": "Putative glutathione-specific gamma-glutamylcyclotransferase 2", "aln": "-------------------------------------------------------------------------MWVFGYGSLIWKVDFPYQDKLVGYITNYSRRFWQGSTDHRGVPGKPGRVVTLVE------------------------DPGGS-VWGVAYKLPVGKEEEVKTYLDFREKGGYRTTTVIFYPKDST-------------------TKPFS-VLLYIGTCDNPNYLG-PAPLEDIAEQIFNAAGPSGRNTEYLFELADSIRKLVPEDADEHLFSLEKLVKERLEGK--------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQG1-1", "uniprot_id": "CHAC2_MOUSE", "id": "Q9CQG1-1", "name": "Putative glutathione-specific gamma-glutamylcyclotransferase 2", "aln": "-------------------------------------------------------------------------MWVFGYGSLIWKVDFPYQDKLVGYITNYSRRFWQGSTDHRGVPGKPGRVVTLVE------------------------DPGGS-VWGVAYKLPVGKEEEVKTYLDFREKGGYRTTTVIFYPKDST-------------------TKPFS-VLLYIGTCDNPNYLG-PAPLEDIAEQIFNAAGPSGRNTEYLFELADSVRKLVPEDADEHLFSLEKLVKERLEGK--------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WUX2-1", "uniprot_id": "CHAC2_HUMAN", "id": "Q8WUX2-1", "name": "Glutathione-specific gamma-glutamylcyclotransferase 2", "aln": "-------------------------------------------------------------------------MWVFGYGSLIWKVDFPYQDKLVGYITNYSRRFWQGSTDHRGVPGKPGRVVTLVE------------------------DPAGC-VWGVAYRLPVGKEEEVKAYLDFREKGGYRTTTVIFYPKDPT-------------------TKPFS-VLLYIGTCDNPDYLG-PAPLEDIAEQIFNAAGPSGRNTEYLFELANSIRNLVPEEADEHLFALEKLVKERLEGKQNLNCI--------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q4KMJ1-1", "uniprot_id": "CHAC2_DANRE", "id": "Q4KMJ1-1", "name": "Putative glutathione-specific gamma-glutamylcyclotransferase 2", "aln": "-------------------------------------------------------------------------MWVFGYGSLIWKVDFPYEDKRVGFVKGFSRRFWQGSTDHRGVPGKPGRVVTLIE------------------------DPEGC-VWGVAYKLPSGQEQEVKEYLDYREKGGYGVITVTFHPKDEQ-------------------QQPMQDTLLYIGSCDNPNYLG-PAPLETIAQQIVKSVGPSGKNTDYLFELADALRQLVPEDLDDHLFSLERLVKQLQEQEDMD-----------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VYK7-1", "uniprot_id": "Q9VYK7_DROME", "id": "Q9VYK7-1", "name": "glutathione-specific gamma-glutamylcyclotransferase", "aln": "MLDFLTELRSSGSRADQLPGNIYTEFFANVIEEPREHGCKSADQDFTQGFSMLRTFDTENSNQLEPPAATDADVWIFGYGSLVWKTDFPYIDRRRGFVWGFKRRFYQHSIDHRGIPERPGRVVTLLPG-----------------------DPAQDRVYGVAYRIAASQKGAVLDHLDYREKNGYERCSLEFHEYPTDG------------------AEPIQ-VIMYVATQANDSYAGDVWQVPCIARQIFSSAGPSGPNREYLFNLAAAMDQLFPGAVDEHLEELVACVKRYIVEDEPQLIRHALLHEISGILEEEQLAEQAHQLEKLLERCQKPGGREWLIYAALQAKNKS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32656-1", "uniprot_id": "CHAC_YEAST", "id": "P32656-1", "name": "Glutathione-specific gamma-glutamylcyclotransferase", "aln": "------------------------------------------------------------------MTNDNSGIWVLGYGSLIYKPPSHYTHRIPAIIHGFARRFWQSSTDHRGTPANPGRVATLIPYEDIIRQTAFLKNVNLYSESAPIQDPDDLVTIGVVYYIPPEHAQEVREYLNVREQNGYTLHEVEVHLETNREHEAELGEALEQLPRHNKSGKRVLLTSVYIGTIDNEAFVG-PETVDETAKVIAVSHGPSGSNYEYLAKLEQALAQMPIMKERGRITDHYLTALLETVNKYR------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*::*****::* * .: . : .: ***:* * **** * .****.**: ** . **.* :. : * :*: **:.** : .: : . . :*:.: * : * : *. * : **** * :** :* :: :: :: . . ", "identical_positions": 48, "similar_positions": 48, "identity": "13.6%" }, { "cls_id": "homologset.agr.RGD:1309121", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GIW9-1", "uniprot_id": "A0A8I6GIW9_RAT", "id": "A0A8I6GIW9-1", "name": "", "aln": "MEPDSVIEDKTIELMCSVPRSLWLGCANLVESMCALSCLQSMPSVR-CLQNTSVMEDQNEDESPKKSALWQVGMISNGTSSVIVSRKRPSEGNYQKEKDLCIKYFDQWSESDQVEFVEHLISRMCHYQHGHINSYLKPMLQRDFITALPEQGLDHIAENILSYLDARSLCAAELVCKEWQRVISEGMLWKKLIERMVRTDPLWKGLSERRGWDQYLFKNRPTDGP-PNSFYRSLYPKIIQDIETIESNWRCGRHNLQRIQCRSENSKGVYCLQYDDDKIISGLRDNSIKIWDKSSLECLKVLTGHTGSVLCLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDFLNVPPSAQNETRSPS----RTYTYISR---------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5SRY7-1", "uniprot_id": "FBW1B_MOUSE", "id": "Q5SRY7-1", "name": "F-box/WD repeat-containing protein 11", "aln": "MEPDSVIEDKTIELMCSVPRSLWLGCANLVESMCALSCLQSMPSVR-CLQ------------------------ISNGTSSVIVSRKRPSEGNYQKEKDLCIKYFDQWSESDQVEFVEHLISRMCHYQHGHINSYLKPMLQRDFITALPEQGLDHIAENILSYLDARSLCAAELVCKEWQRVISEGMLWKKLIERMVRTDPLWKGLSERRGWDQYLFKNRPTDGP-PNSFYRSLYPKIIQDIETIESNWRCGRHNLQRIQCRSENSKGVYCLQYDDDKIISGLRDNSIKIWDKSSLECLKVLTGHTGSVLCLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDFLNVPPSAQNETRSPS----RTYTYISR---------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UKB1-1", "uniprot_id": "FBW1B_HUMAN", "id": "Q9UKB1-1", "name": "F-box/WD repeat-containing protein 11", "aln": "MEPDSVIEDKTIELMCSVPRSLWLGCANLVESMCALSCLQSMPSVR-CLQ------------------------ISNGTSSVIVSRKRPSEGNYQKEKDLCIKYFDQWSESDQVEFVEHLISRMCHYQHGHINSYLKPMLQRDFITALPEQGLDHIAENILSYLDARSLCAAELVCKEWQRVISEGMLWKKLIERMVRTDPLWKGLSERRGWDQYLFKNRPTDGP-PNSFYRSLYPKIIQDIETIESNWRCGRHNLQRIQCRSENSKGVYCLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDFLNVPPSAQNETRSPS----RTYTYISR---------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8QFQ6-1", "uniprot_id": "FB11A_DANRE", "id": "A0A2R8QFQ6-1", "name": "F-box and WD repeat domain-containing 11-A", "aln": "MDPD--KEDKTLELMCSLPRSVWLGCSSVAESLCALRCLQSLPSSRAHNQNMTGMESQINTDEVSPKK---TTVFKLGNGSLAGSRKRPSQGSFDKEKDLCIQLFDQWSESDQVEFVEHLIARMCHYQHGHINSYLKPMLQRDFITALPARGLDHIAENILSFLDARSLCSAELVCREWQRVISDGMLWKKLIERMVRTDPLWKGLSERHQWEKYLFKNRTNEVP-PNSYYHSLYPKIIQDIETIEANWRCGRHNLQRIQCRSENSKGVYCLQYDDDKIISGLRDNSIKIWDKQSLECLKVLTGHTGSVLCLQYDERVIVTGSSDSTVRVWDVSSGEVLNTLIHHNEAVLHLRFCNGLMVTCSKDRSIAVWDMASATDISLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDFLNVSSNGQSDGRSPS----RTYTYVSR---------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A2R8RWN9-1", "uniprot_id": "FB11B_DANRE", "id": "A0A2R8RWN9-1", "name": "F-box and WD repeat domain-containing 11-B", "aln": "--------------MFDLKQTLLL--------ISELMHLFLLR-----LQNTSVMDPQT--ADRSPK----ITLIKVSNGPLTGSRKRPSEGNYEKEKDVCIQLFDQWSEADQVEFVEHLISRMCHYQHGHINSYLKPMLQRDFITALPAQGLDHIAENILSFLDARSLCSAELVCKEWQRVISEGMLWKKLIERMVRTDPLWKGLSERHQWEKYLFKNRTTEVP-PNSYYRSLYPKIIQDIETIEANWRCGRHNLQRIQCRSENSKGVYCLQYDDEKIISGLRDNSIKIWDKQTLECLKILTGHTGSVLCLQYDERVIVTGSSDSTVRVWDVNSGEVLNTLIHHNEAVLHLRFCNGLMVTCSKDRSIAVWDMASPTDISLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDFLNVSTNGQTEGRSPS----RTYTYISR---------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KHK1-1", "uniprot_id": "A0A0B4KHK1_DROME", "id": "A0A0B4KHK1-1", "name": "", "aln": "--------------MMKMETDKIMDETNSNAQAFTTTMLYDP------------------------------------------VRKKDSSPTYQTERELCFQYFTQWSESGQVDFVEHLLSRMCHYQHGQINAYLKPMLQRDFITLLPIKGLDHIAENILSYLDAESLKSSELVCKEWLRVISEGMLWKKLIERKVRTDSLWRGLAERRNWMQYLFKPRPGQTQRPHSFHRELFPKIMNDIDSIENNWRTGRHMLRRINCRSENSKGVYCLQYDDGKIVSGLRDNTIKIWDRTDLQCVKTLMGHTGSVLCLQYDDKVIISGSSDSTVRVWDVNTGEMVNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMTSPSEITLRRVLVGHRAAVNVVDFDEKYIVSASGDRTIKVWSTSSCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNSIRLWDIECGACLRVLEGHEELVRCIRFDTKRIVSGAYDGKIKVWDLVAALDPRAASNTLCLNTLVEHTGRVFRLQFDEFQIVSSSHDDTILIWDFLNFTPNENKTGRTPSPALMEHXHFVQRQLRELHLQSSSEGEEDDDADEDDEDDFEEEDSRNDAGAFMGGYVRHRDAGGSGSVTGSGSDPESDDLDFDIDVENINDYDE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .: : * **: *. .::.*:::*:: * ****:.**:*****::********:**:************ ** :***********:***.** ::****:** ****:********** ****.**:**:**: * :**** *. : *:*:::.*:***::**::** *** *** *:**:**************** **:******:*****: *:*:* * ************::**::************.:**::****** ******** **:***************:*.::*:******************:******************:*******************************:****************************.***************** *******.:.****.*****:*************:***************.... :. *:** . ::.* ", "identical_positions": 368, "similar_positions": 87, "identity": "56.36%" }, { "cls_id": "homologset.agr.RGD:1309122", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9DAM3-1", "uniprot_id": "HSPB9_MOUSE", "id": "Q9DAM3-1", "name": "Heat shock protein beta-9", "aln": "----------------------------------MQRVGSSFSTGQREPGENRVASRCPSVALAERNQVATLPVRLLRDEVQG---NGCEQPSFQIKVDAQGFAPEDLVVRIDGQNLTVTGQRQHESNDPSRGRYRMEQSVHRQMQLPPTLDPAAMTCSLTPSGHLWLRGQNKCLPPPEAQTGQSQKPRRGGPKSSLQNES-VKNP-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LPF7-1", "uniprot_id": "A0ABK0LPF7_RAT", "id": "A0ABK0LPF7-1", "name": "", "aln": "MGTVGGPFLFAPAPRMWGGGGGSPRALRQQLHSRMQRVGSSFSTGQREPGENRVASRCPSVALSERNQAATLPVRLLKDDLAAAHANGCEEPSFQMKLDAHGFAPEDLVVRIDGQNLMVTGKRQQESNDPSRGRYRLEQSVHRQMQLPMTLDPAAMTCSLTPSGHLWFKGQNKCLPLPEAQTG----PQTGQALRFKRGSSKCPNPP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BQS6-1", "uniprot_id": "HSPB9_HUMAN", "id": "Q9BQS6-1", "name": "Heat shock protein beta-9", "aln": "----------------------------------MQRVGNTFSN------ESRVASRCPSVGLAERNRVATMPVRLLRDSPAAQEDNDHARDGFQMKLDAHGFAPEELVVQVDGQWLMVTGQQQLDVRDPERVSYRMSQKVHRKM-LPSNLSPTAMTCCLTPSGQLWVRGQCVALALPEAQTGPS--PRLGSLGSKASNLTR-----", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *****.:**. *.*********.*:***:.**:*****:*. . *. . .**:*:**:*****:***::*** * ***::* : .**.* **:.*.***:* ** .*.*:****.*****:**.:** .*. ****** *: * . : ", "identical_positions": 87, "similar_positions": 42, "identity": "42.03%" }, { "cls_id": "homologset.agr.RGD:1309123", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5RK00-1", "uniprot_id": "RM46_RAT", "id": "Q5RK00-1", "name": "Large ribosomal subunit protein mL46", "aln": "MAAPIGRTLLGVAKGWRQLDRLWAG--SSRGLSLEAAPSSSRSPWRLSGALCLQRPPLITKPLTPLQEEMAGLLQQVE------------VERSLYSDHELRALDE------------------AQRLAKKKADLYDEEQDQDVTLAQDLEDMWEQEFLQ-FRPGARETEADKKNDRTSLHRKLDRNLILLVREKLGDQDLWMLPQVEW-QPGETLRGTAERILATLSENNMEAKFLGNAPCGHYKFKFPKAIRTESDLGVKVFFFKALLLTGDFVQTGKKGRHVWASKEELGDYLQ-PKYLAQVRRFLLDL------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EQI8-1", "uniprot_id": "RM46_MOUSE", "id": "Q9EQI8-1", "name": "Large ribosomal subunit protein mL46", "aln": "MAAPVGRTLLGLARGWRQLDRFWAG--SSRGLSLEAASSSSRSPWRLSGALCLQRPPLITKALTPLQEEMAGLLQQIE------------VERSLYSDHELRALDE------------------AQRLAKKKADLYDEEQEQGITLAQDLEDMWEQAFLQ-FRPGARETEADKKNDRTSLHRKLDRNLVLLVREKLGDQDVWMLPQVEW-QPGETLRGTAERILATLSENNMEAKFLGNAPCGHYKFKFPKAIQTESDLGVKVFFFKALLLTGDFVQAGKKSRHVWASKEELGDYLQ-PKYLAQVRRFLLDSDGLSCL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H2W6-1", "uniprot_id": "RM46_HUMAN", "id": "Q9H2W6-1", "name": "Large ribosomal subunit protein mL46", "aln": "MAAPVRRTLLGVAGGWRRFERLWAGSLSSRSLALAAAPSSNGSPWRLLGALCLQRPPVVSKPLTPLQEEMASLLQQIE------------IERSLYSDHELRALDE------------------NQRLAKKKADLHDEEDEQDILLAQDLEDMWEQKFLQ-FKLGARITEADEKNDRTSLNRKLDRNLVLLVREKFGDQDVWILPQAEW-QPGETLRGTAERTLATLSENNMEAKFLGNAPCGHYTFKFPQAMRTESNLGAKVFFFKALLLTGDFSQAGNKGHHVWVTKDELGDYLK-PKYLAQVRRFVSDL------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W086-1", "uniprot_id": "Q9W086_DROME", "id": "Q9W086-1", "name": "Large ribosomal subunit protein mL46", "aln": "----MLRRIVQVG---------------ARELSRAQSSTASAEKWDLYAGVLVERLPVVSKSLNPLEKQFQDLLWRVE------------YENSLKSDHELKHEREI----------------VQAELIKQGKIQVDLEDAGSKQTAQDLKDAYVEELKK-FQLGSRTTPDDQANRTTSTDRCLDDTLYLLVQQKLGQQEHLILPQGKR-EEGESMRQTAERVLRESCGQELQVLFYGNAPVGFHKYKYPRNQRTET-VGAKVFFYRASLRSGQVPEN--LTKFEWLPKEALNEKLTNTAYAQSVKKFLL--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36528-1", "uniprot_id": "RM17_YEAST", "id": "P36528-1", "name": "Large ribosomal subunit protein mL46", "aln": "----MKVNLMLK-----------------RGLATATATASS-APPKIKVGVLLSRIPIIKSELNELEKKYYEYQSELEKRLMWTFPAYFYFKKGTVAEHKFLSLQKGPISKKNGIWFPRGIPDIKHGRERSTKQEVKLSDDSTVAFSNNQKEQSKDDVNRPVIPNDRITEADRSNDMKSLERQLSRTLYLLVKDKSG---TWKFPNFDLSDESKPLHVHAENELKLLSGDQIYTWSVSATPIG--VLQDERNRTAEFIVKSHILAGKFDLVAS---KNDAFEDFAWLTKGEISEYVP-KDYFNKTEFLLADN------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: * *: :.::. : .: :.* *::.. *. *::: .:* :.. ::*:: : :. . .: ::: :: : . : . . * * *. * .* .* *. .* ***::* * :*: . : .:.:: **. * . ::: . . :* * : : :* : ::: : * :. : . * .* :.: : * ... :: ", "identical_positions": 32, "similar_positions": 93, "identity": "10.06%" }, { "cls_id": "homologset.agr.RGD:1309124", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5PPI9-1", "uniprot_id": "TTLL1_RAT", "id": "Q5PPI9-1", "name": "Polyglutamylase complex subunit TTLL1", "aln": "---------------------------------------------------------------MAG--------RVKWVTDIEKSVLINNFEKRGWVQVTENE-DWNFYWMSVQTIRNVFSVETGYRLSDDQIVNHFPNHYELTRKDLMVKNIKRYRKELEKEGSPLAEKDENG--------KYLYLDFVPVTYMLPADYNLFVEEFRKSPSSTWIMKPCGKAQGKGIFLINKLSQIKKWSRDSKTSSFVSQ-STKEAYVISLYINNPLLIGGRKFDLRLYVLVSTYRPLRCYMYKLGFCRFCTVKYTPSTSELDNMFVHLTNVAIQKHGEDYNHIHGGKWTVNNLRLYLESTRGREVTSKLFDEIHWIIVQSLKAVAPVMNNDKHCFECYGYDIIIDDKLKPWLIEVNASPSLTSSTANDRILKYNLINDTLNIAVPNGEIPDCKWNKSPPKEVLGNYEILYDEELAQGDG------------AERELRSRPGQPVGPRTGRSRDSGRNVLTTWK-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91V51-1", "uniprot_id": "TTLL1_MOUSE", "id": "Q91V51-1", "name": "Polyglutamylase complex subunit TTLL1", "aln": "---------------------------------------------------------------MAG--------RVKWVTDIEKSVLINNFEKRGWIQVTENE-DWNFYWMSVQTIRNVFSVETGYRLSDDQIVNHFPNHYELTRKDLMVKNIKRYRKELEKEGSPLAEKDENG--------KYLYLDFVPVTYMLPADYNLFVEEFRKSPSSTWIMKPCGKAQGKGIFLINKLSQIKKWSRDSKTSSFVSQ-STKEAYVISVYINNPLLIGGRKFDLRLYVLVSTYRPLRCYMYKLGFCRFCTVKYTPSTSELDNMFVHLTNVAIQKHGEDYNHIHGGKWTVNNLRLYLESTRGREVTSKLFDEIHWIIVQSLKAVAPVMNNDKHCFECYGYDIIIDDKLKPWLIEVNASPSLTSSTANDRILKYNLINDTLNIAVPNGEIPDCKWNKSPPKEVLGNYEILYDEELAQGDG------------AERELRNRPGQPVGPRAGRSRDSGRSVLTTWK-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95922-1", "uniprot_id": "TTLL1_HUMAN", "id": "O95922-1", "name": "Polyglutamylase complex subunit TTLL1", "aln": "---------------------------------------------------------------MAG--------KVKWVTDIEKSVLINNFEKRGWVQVTENE-DWNFYWMSVQTIRNVFSVEAGYRLSDDQIVNHFPNHYELTRKDLMVKNIKRYRKELEKEGSPLAEKDENG--------KYLYLDFVPVTYMLPADYNLFVEEFRKSPSSTWIMKPCGKAQGKGIFLINKLSQIKKWSRDSKTSSFVSQ-SNKEAYVISLYINNPLLIGGRKFDLRLYVLVSTYRPLRCYMYKLGFCRFCTVKYTPSTSELDNMFVHLTNVAIQKHGEDYNHIHGGKWTVSNLRLYLESTRGKEVTSKLFDEIHWIIVQSLKAVAPVMNNDKHCFECYGYDIIIDDKLKPWLIEVNASPSLTSSTANDRILKYNLINDTLNIAVPNGEIPDCKWNKSPPKEVLGNYEILYDEELAQGDG------------ADRELRSRQGQSLGPRAGRSRDSGRAVLTTWK-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P2G8-1", "uniprot_id": "A0A8M1P2G8_DANRE", "id": "A0A8M1P2G8-1", "name": "Polyglutamylase complex subunit TTLL1", "aln": "---------------------------------------------------------------MAG--------KVKWVTDIEKSVLINNFEKRGWIQVTDSE-DWNFYWMSIQTIRTVFSVDTGYRLTDDQMVNHFPNHYELTRKDLMIKNIKRYRRELEKENSALAEKDDSG--------KYIYLDFVPVTFMLPADYNLFVEEFRKSPSSTWIMKPCGKAQGKGIFLINKLSQIKKWSRDSRTSTFVAANSGKEAYVISLYIDNPLLIGGKKFDLRLYVLVTTYRPLKCYMYKLGFCRFCTVKYTPSTSELDNMFVHLTNVAIQKHGDDYNHVHGGKWTVSNLRLYLESTRGPDVTNHLFDQIHWIIVQSLKAVAPVMNNDKHCFECYGYDIIIDDRLKPWLIEVNASPSLTSSTANDRILKYNLINDTLNIVTPNAEIPDCRWNRSLPKEALGHYQVLYDEEQALSES------------TERDLRSRSGHSLGSKSTR-QSGVRPFPATWK-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VZ97-1", "uniprot_id": "Q9VZ97_DROME", "id": "Q9VZ97-1", "name": "Polyglutamylase complex subunit TTLL1", "aln": "MAVVWDMSQWTQAWRIDSLHPTVRSSGTRTTTSGTIMYGRTSVGANQSVTNGNSNSGANSGGGASGGAQGHDKLKIGFCTDLDKSVLVNNFEKRGWHQVNGDD-DWHFYWAGVQTCRNIFSVDSGYRMHDNQMINHFPNHYELSRKDLLVKNIKRYRKDLERDGNPLAEKTESNNSS---GTRYLYLDFVPTTFVLPADYNMFVEEYRKFPLSTWIMKPCGKSQGAGIFLINKLSKLKKWSREAKG-PFHPQ-IAKESYVISRYIDNPLLIGGKKFDLRLYVLVASFRPLKAYLFKQGFCRFCTVKYDTSVTELDNMYVHLTNVSVQKHGGEYNTLHGGKWSVQNLALYLEGTRGKEVTDRLFGAISWLIVHSLRAVAPVMASDRHCFECYGYDIIIDNALKPWLVEVNASPSLTSTTVNDRILKYKLIDNILSVVLPPDGVPDVRWNKVPSADALGNFELLIDEELAAQDE------------QHQNSSS------NTHSKTSKMGSR-----WK-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VX74-1", "uniprot_id": "Q9VX74_DROME", "id": "Q9VX74-1", "name": "Polyglutamylase complex subunit TTLL1", "aln": "------MSTRRQTSPLRNLRQKCGGSCTSDDDLPEVKLITQPINGLHYIRNRLRPPK-----SRNG---------IYYSTDWDKSALVSNFQKRGWLQVPSFNGEWNFYWACTQNCRYIFGIDHPYRMRSDQVINHFPNSIELSRKDLLIKNIKRYRKDLERRGDPLAQSHPPDTKLGIGGTRYKHLDIIPMTFVLPSDYQMFVEVFHRNPASTWIVKPCSKSQGVGIYLVNKLSKLKKFAYDART--FYPQ-INRDTCVISKYIDNPLLIGGKKFDLRLFVLVTTFNPLKAYLYKEGFCRFCTEKYD--ETEIDNVFMHLTNVSIQKTNQEYNSIHGGKWPLQNLWLYLDSLRGEGVSDMLWSRITATIRHSLDAVAPVMANDRHCFEVYGYDIIIDNNLKPWLIEINTSPSMHSTTTNDRMLKSRLIDNVLDVVVPPNCMPNEHWDKTPNPELLKNFTVLMPISPCKPKEQVPVRRKGRLSKKKKSKSTTASSGICSFTPPPAEGETKIKRSNKVVKRL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : : ** :**.*:.**:**** ** : :*:*** *. * :*.:: **: .:*::***** **:****::*******::**: ...**:. . :* :**::* *::**:**::*** ::: * ****:***.*:** **:*:****::**:: ::: * . ::: *** **:*******:******:***:::.**:.*::* ******* ** :*:**:::*****::** . :** :*****.:.** ***:. ** *:. *:. * * :** ****** .*:**** ********: *****:*:*:***: *:*.***:** .**:: *.:. * :*: :*:: : * :: :* . . . .:. . . : . * ", "identical_positions": 188, "similar_positions": 126, "identity": "36.08%" }, { "cls_id": "homologset.agr.RGD:1309125", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZFK5-1", "uniprot_id": "D3ZFK5_RAT", "id": "D3ZFK5-1", "name": "Signal peptidase complex subunit 1", "aln": "MARGGARGCASPSETSASGATAEERR-LAGRPGCFRYRTSQATLLNSQ------LPSFHCRYQSSATMLEHLSSLPTQMDYKGQKLAEQMFQGIILFSAIVGFIYGYVAEQFGWTVYIVMAGFAFSCLLTLPPWPIYRRHPLKWLPVQDSGTEDKKSGDRKIKRHAKNN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D958-1", "uniprot_id": "SPCS1_MOUSE", "id": "Q9D958-1", "name": "Signal peptidase complex subunit 1", "aln": "MARGGARGCPCPSETSASGATAEVKR-SAGRP-CSRYRPPQTLLLNNR------LRPFRCRYRSSATMLEHLSSLPTQMDYKGQKLAEQMFQGIILFSAIVGFIYGYVAEQFGWTVYIVMAGFAFSCLLTLPPWPIYRRHPLKWLPVQDLGTEDKKSGDRKIKRHAKNN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y6A9-1", "uniprot_id": "SPCS1_HUMAN", "id": "Q9Y6A9-1", "name": "Signal peptidase complex subunit 1", "aln": "MARGGDTGCTGPSETSASGAAAIALPGLEGPATDAQCQTLPLTVLKSRSPSPRSLPPALSCPPPQPAMLEHLSSLPTQMDYKGQKLAEQMFQGIILFSAIVGFIYGYVAEQFGWTVYIVMAGFAFSCLLTLPPWPIYRRHPLKWLPVQESSTDDKKPGERKIKRHAKNN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VAL0-1", "uniprot_id": "SPCS1_DROME", "id": "Q9VAL0-1", "name": "Signal peptidase complex subunit 1", "aln": "-------------------------------------------------------------------MLD----IQTHMDFAGQGKAERWSRFIITFFGIVGLVYGAFVQQFSQTVYILGAGFVLSSLITIPPWPLYRRNALKWQKPIDTDAKSSSSESGDEGKKKKKQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P46965-1", "uniprot_id": "SPC1_YEAST", "id": "P46965-1", "name": "Signal peptidase complex subunit 1", "aln": "---------------------------------------------------------------MSEILQDVQRKLVFPIDFPSQRKTEKFQQLSLMIGALVACILGFAQQSLKVLLTAYGISCVITLICVLPAYPWYNKQKLRWAQP-KIEINVDQYD-----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : :*: .* :*: : : : .:*. : * :.: : . .:: : .:*.:* *.:: *:* . . .. ", "identical_positions": 10, "similar_positions": 36, "identity": "5.92%" }, { "cls_id": "homologset.agr.RGD:1309127", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A2RT62-1", "uniprot_id": "FXL16_MOUSE", "id": "A2RT62-1", "name": "F-box/LRR-repeat protein 16", "aln": "------------------------------------------------------------------------------------------------------------MSSPGIDGDP-----KPP--CLPRNGLVKLPG----------------------------------QPNGLGAASITKGTPAAKNRPCQPP-----PPPTLPPPSLATPLSRVALAGGPCPP-----------ASGPASGPVSGPPVER-------------------------------PP-------LATDEKILNGLFWYFSACEKCILAQVCKAWRRVLYQ-PKFWAGLTPVLHAKELYNVLPGGEKEFVNLQGFAARGFEGFCLVGVSD-------LDICEFIDN--YSLSKKGVKAMSLKRSTITDAGLEVMLEQMQGVVRLELSGCNDFTEAGLWSSLSARITSLS---------------------VSDCINVADDAIAAISQLLPNLAELSLQAYHVTDTALAYFTARQG-----HSTHTLRLLSCWEITNHGVVNVVHS---------------------------------LPNLTSLSLSGCSKVTDDGVELVAENLRK----------------------------------------------LRSLDLSWCPRITDMALEYVACDLHRLEELVLD--RCVRITDTG--LSYLSTMSSLRSLYLRWCCQVQDFGLKHLLAMRNLRLLSLAGCPLLTTTGLSG-LVQLQELEELELTNCPGATP---------------------------ELFKYFSQHLPRCLVIE-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5MJ12-1", "uniprot_id": "FXL16_RAT", "id": "Q5MJ12-1", "name": "F-box/LRR-repeat protein 16", "aln": "------------------------------------------------------------------------------------------------------------MSSPGIDGDP-----KPS--CLPRNGLVKLPG----------------------------------QPNGLGAASITKGTPAAKNRPCQPP-----PPPTLPPPSLATPLSRVALAGGPCPP-----------ASGPASGPVPGPPVER-------------------------------PP-------LATDEKILNGLFWYFSACEKCILAQVCKAWRRVLYQ-PKFWAGLTPVLHAKELYNVLPGGEKEFVNLQGFAARGFEGFCLVGVSD-------LDICEFIDN--YSLSKKGVKAMSLKRSTITDAGLEVMLEQMQGVVRLELSGCNDFTEAGLWSSLSARITSLS---------------------VSDCINVADDAIAAISQLLPNLAELSLQAYHVTDTALAYFTARQG-----HSTHTLRLLSCWEITNHGVVNVVHS---------------------------------LPNLTSLSLSGCSKVTDDGVELVAENLRK----------------------------------------------LRSLDLSWCPRITDMALEYVACDLHRLEELVLD--RCVRITDTG--LSYLSTMSSLRSLYLRWCCQVQDFGLKHLLAMRSLRLLSLAGCPLLTTTGLSG-LVQLQELEELELTNCPGATP---------------------------ELFKYFSQHLPRCLVIE-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N461-1", "uniprot_id": "FXL16_HUMAN", "id": "Q8N461-1", "name": "F-box/LRR-repeat protein 16", "aln": "------------------------------------------------------------------------------------------------------------MSSPGIDGDP-----KPP--CLPRNGLVKLPG----------------------------------QPNGLGAASITKGTPATKNRPCQPP-----PPPTLPPPSLAAPLSRAALAGGPCTP-----------AGGPASALAPGHPAER-------------------------------PP-------LATDEKILNGLFWYFSACEKCVLAQVCKAWRRVLYQ-PKFWAGLTPVLHAKELYNVLPGGEKEFVNLQGFAARGFEGFCLVGVSD-------LDICEFIDN--YALSKKGVKAMSLKRSTITDAGLEVMLEQMQGVVRLELSGCNDFTEAGLWSSLSARITSLS---------------------VSDCINVADDAIAAISQLLPNLAELSLQAYHVTDTALAYFTARQG-----HSTHTLRLLSCWEITNHGVVNVVHS---------------------------------LPNLTALSLSGCSKVTDDGVELVAENLRK----------------------------------------------LRSLDLSWCPRITDMALEYVACDLHRLEELVLD--RCVRITDTG--LSYLSTMSSLRSLYLRWCCQVQDFGLKHLLALGSLRLLSLAGCPLLTTTGLSG-LVQLQELEELELTNCPGATP---------------------------ELFKYFSQHLPRCLVIE-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VTL8-1", "uniprot_id": "Q9VTL8_DROME", "id": "Q9VTL8-1", "name": "F-box/LRR-repeat protein 16", "aln": "-----MSSISAQGVVERASAELSKRINGLGLRSKHHHSSTSSGAGGAGDAASPAGATPTP-----AAPSGKTSVMERVTNALCGGGNSNSNSGSNSSNSNTSSASATAATSPASNANPPQTPDKPSRGSSPSPGGITMPGGQSQVQNSTHHLLQQQQQQQQHMQLQQ----SQQQHLQLQASTLINSNHHVMVGPAPPTGMPLGAPPTPTVKSIAKQMN-ITIPGGGVNPGSPTFSTMGMVAAQKAAASAGGTPLQLRKQLPNPHLHHPYGSMGINAASPLIMQHQLHPPPIHSIEQLMLDDRFLSRFFQYFSPYERRILAQVCIKWRDTLYRSPRYWSGLLPTLQCRELR-QMPGCDRGKLYNS-LIRRGFHALGLVGASD-------EDALDVVHS--FPLASKHVHSLSLRCSSISDRGLETLLDHLQSLFELELAGCNEVTEAGLWACLTPRIVSLS---------------------LADCINIADEAVGAVAQLLPSLYEFSLQAYHVTDAALGYFSPKQS-----HSLSILRLQSCWELTNHGIVNIVHS---------------------------------LPHLTVLSLSGCSKLTDDGVELIAENLQK----------------------------------------------LRALDLSWCPRITDASLEYIACDLNQLEELTLD--RCVHITDIG--VGYISTMLSLTALFLRWCSQVRDFGLQHLCSMRNLQVLSLAGCPLLTSSGLSS-LIQLRHLQELELTNCPGASH---------------------------ELFDYLKEHLPRCLIIE-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06479-1", "uniprot_id": "YL352_YEAST", "id": "Q06479-1", "name": "F-box protein YLR352W", "aln": "MPDLKSKTLSSQSLGAAIPPEIVYQILTYQFRDLLRNDHPGTAEKFNENLTTFVKSNLTVNKTFSHICQVLIYRYCNLTTAKRFHGLLQTLKGNRCLCNKIEVADFQELTSIGLGRSSEMNKMIKNLTNETLLEFLMLTKANLREFLACENIQDDLDDNIIKYILSPGKVLSVVDFCGCSGTTFTESFIKALDKYYPNKS---IDQYRLEPIQQNYQITCLGLNDCIDLPSHVLWKILKMLPELQKLDLSHTSIDDSTLYHGIPHWKN--------------------LTHLSLATCLQVTPRAVLEFFSHHPTITDPDNTSTLEWLNVSVIAHSSSWNEVHTMFLLKKLCQHGHNKTLQYLNIGGLPLHVAPSFGEDPISESTYYYQCRDSLQFIKWNFPKLKSLSIKGNSIPISTLVEFLTPIDQDHPNCAQKLKFLNISGNSYVNKWTIQDSLLYTCSPSLVALEVSFDSWQQIEKLNDRHEIIAYRYKNPNSVIKDISTAEQVKWKCYIDSSYGRRYWLYKTDPFLNRDDLDSKSNLTRYDFEGHKIIEIINQPDFLKFAQSKIMLGCGLVPQSGIRRKLCYRDLKPPVSQFLNRKGAISLGDTPLPIITPTLPRGGWRIIHNEDDNNSHVEDSQNHVNAIPRRNSLLSRPTLRSNNGSSSANPFAINVSPASQIRDGLYWDRSVHDLRELSLQEQRIQELADEQQELRTIANFEETDDEYLHDPDLQRRRSQLHLFESSRSRSGNKTRPSLTGEHSSSASFLSFSHFNHLHKRKNYYFTHPDEFVYDPKDPLTTQRYRLHFEIVNEYQVFGCIERGMYRYYSLKA", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* . . .. . : :. : .::: :. . . :. : . * . : . * : : :* :... :.. . : . * : . : ::* . : : : .: *: * :.:. * . ::. *: *:: : :: : .*:: . . : .. *: . : : * : * . :: : :.. :.. :.* :. . *: : . .. : ::: .* ::::::. * *. .*. .: * : ::: .* : ..: :. .* * .:: *.** *: * .::* : ::.: . :*: : . ** : . : .* . *. ::.: .::.*. : : ::* :.. : * :: ", "identical_positions": 39, "similar_positions": 170, "identity": "4.7%" }, { "cls_id": "homologset.agr.RGD:1309128", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AL98-1", "uniprot_id": "A0A8I6AL98_RAT", "id": "A0A8I6AL98-1", "name": "poly(A)-specific ribonuclease", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MCGYGFLQLLTSVAGLIG----MP--KEKYDPPDPRRIYTIMSAEEVANGKKSHWAELEIS-GRVRSLSTSLWSLTHLTALHLNDNNLARIPPDIAKLHNLVYLDLSSNKLRSLPAELGNMVSLRELLLNDNYLRVLPYELGRLFQLQTLGLTGNPLSQDIMSLYQDPDGTRKLLNFMLDN------------LAVHPEQLPPRPWITLKERDQILP----SASFTVMCYNVLCDKYATRQLYGYCPSWALNWEYRKKGIMEEIVNWDADIISLQEVETEQYFTLFLPALKDRGYDGFFSPKSRAKIMSEQERKHVDGCAIFFKTEKFTLVQKHTVEFNQVAMANS--DGSEAMLNRVMTKDNIGVAVVLEVHKELFGTGMKPIHAADKQLLIVANAHMHWDPEYSDVKLIQTMMFVSEVKNILEKASS--RPGSPTADPNSIPLVLCADLNSLPDSGVVEYLSNGGVADN-HKDFKELRYNECLMNFSCSGKNGSSEGRITHGFQLKSAYENN-LMPYTNYTFDFKGVIDYIFYSKTHMNVLGVLGPLDPQWLVENNITGCPHPHIPSDHFSLLTQLELHPPLLPLVNGVHLPNRR----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VEG6-1", "uniprot_id": "CNO6L_MOUSE", "id": "Q8VEG6-1", "name": "CCR4-NOT transcription complex subunit 6-like", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRLIG----MP--KEKYDPPDPRRIYTIMSAEEVANGKKSHWAELEIS-GRVRSLSTSLWSLTHLTALHLNDNNLARIPPDIAKLHNLVYLDLSSNKLRSLPAELGNMVSLRELLLNDNYLRVLPYELGRLFQLQTLGLTGNPLSQDIMSLYQDPDGTRKLLNFMLDN------------LAVHPEQLPPRPWITLKERDQILP----SASFTVMCYNVLCDKYATRQLYGYCPSWALNWEYRKKGIMEEIVNWDADIISLQEVETEQYFTLFLPALKDRGYDGFFSPKSRAKIMSEQERKHVDGCAIFFKTEKFTLVQKHTVEFNQVAMANS--DGSEAMLNRVMTKDNIGVAVVLEVHKELFGTGMKPIHAADKQLLIVANAHMHWDPEYSDVKLIQTMMFVSEVKNILEKASS--RPGSPTADPNSIPLVLCADLNSLPDSGVVEYLSNGGVADN-HKDFKELRYNECLMNFSCSGKNGSSEGRITHGFQLKSAYENN-LMPYTNYTFDFKGVIDYIFYSKTHMNVLGVLGPLDPQWLVENNITGCPHPHIPSDHFSLLTQLELHPPLLPLVNGVHLPNRR----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96LI5-1", "uniprot_id": "CNO6L_HUMAN", "id": "Q96LI5-1", "name": "CCR4-NOT transcription complex subunit 6-like", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRLIG----MP--KEKYDPPDPRRIYTIMSAEEVANGKKSHWAELEIS-GRVRSLSTSLWSLTHLTALHLNDNYLSRIPPDIAKLHNLVYLDLSSNKLRSLPAELGNMVSLRELLLNNNLLRVLPYELGRLFQLQTLGLKGNPLSQDILNLYQDPDGTRKLLNFMLDN------------LAVHPEQLPPRPWITLKERDQILP----SASFTVMCYNVLCDKYATRQLYGYCPSWALNWEYRKKGIMEEIVNCDADIISLQEVETEQYFTLFLPALKERGYDGFFSPKSRAKIMSEQERKHVDGCAIFFKTEKFTLVQKHTVEFNQVAMANS--DGSEAMLNRVMTKDNIGVAVVLEVHKELFGAGMKPIHAADKQLLIVANAHMHWDPEYSDVKLIQTMMFVSEVKNILEKASS--RPGSPTADPNSIPLVLCADLNSLPDSGVVEYLSNGGVADN-HKDFKELRYNECLMNFSCNGKNGSSEGRITHGFQLKSAYENN-LMPYTNYTFDFKGVIDYIFYSKTHMNVLGVLGPLDPQWLVENNITGCPHPHIPSDHFSLLTQLELHPPLLPLVNGVHLPNRR----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2BHJ4-1", "uniprot_id": "CNO6L_DANRE", "id": "A2BHJ4-1", "name": "CCR4-NOT transcription complex subunit 6-like", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MP--KEKYDPPDPRRLYTIMSAEEVASGKKSHWTELEIS-GRVRSLSSSLWTLTHLTALHINNNNLSRIPPEIAKLPHLVYLNLSSNKLRSLPAELGNMVTLRELLLNNNCLRVLPYELGRLFQLQTLGLKGNPLSQDILNLYQEPDGTRKLLNYMLDN------------LAVHPEQLPQRPWITLRERDQMMP----TAVFTVMCYNVLCDKYATRQLYGYCPSWALNWEYRKKGIMEEITNCDADIISLQEVETEQYYTFFLETLKDRGYDGFFCPKSRAKLVSEQERKHVDGCGVFFKTEKFALVQKHTVEFNQVAMANS--EGSEVMLNRVMTKDNIGVAVLLEVKKDLFATGLKP--PPEKQLLLVANAHMHWDPEYSDVKLIQTMMFLSELKSIAERASGSINSSSPTSETSSIPIVLCADLNSLPDSGVVEYLSNGGVAEN-HKDFKELRYSDCLTNFSCNGKNGKPDGSITHSFQLKSAYEGN-LMPYTNYTYDFKGVIDYIFFSKTHMSVLGVLGPLETQWLKDNNITGCPHPHIPSDHFSLLAQLEYHPPLPPLN-GLHLPVHSTACESKMLTE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IMX1-1", "uniprot_id": "Q8IMX1_DROME", "id": "Q8IMX1-1", "name": "poly(A)-specific ribonuclease", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MCIFKKRDAYHQAVIMKGNHYKMSRNKDKYDSAN-RRQQIFLSQEDIAAGKKTNWSGLEIT-GCVRNISPSLWEFEHLTALYLNDNQLLRLPADVGMLTSLRTLDLSSNKLRSLPAELGELIQLRELLLNNNFLRVLPYEIGKLFHLVILGLMGNPLQKEFMNIYNEPNGTQKLLTYMLDN------------LSFTVNPPPQRPWLPLAKPNKTRP----ACIFTVMCYNVLCDKYATRQMYGYCPSWALCWEYRKKSIIDEIRHYAADIISLQEIETEQFYHFFLPELKNDGYEGIFSPKSRAKTMSELERKYVDGCAIFFRASKFTLIKESLIEFNQLAMANA--EGSDNMLNRVMPKDNIGLAALLKVKENAWEP--MSEVTQISQPLLVCTAHIHWDPEFCDVKLIQTMMLSNELKTIIDEASHSFRPGH-KNDSNAVQLLLCGDFNSLPDSGVVEFLGKGRVSMD-HLDFKDMGYKSCLQRLLSNDTN-----EFTHSFKLASAYNED-IMPHTNYTFDFKGIIDYIFYTKTGMVPLGLLGPVSNDWLRENKVVGCPHPHIPSDHFPLLVELELMHTASQQAPPNGLINRR----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P31384-1", "uniprot_id": "CCR4_YEAST", "id": "P31384-1", "name": "CCR4-Not complex 3'-5'-exoribonuclease subunit Ccr4", "aln": "MNDPSLLGYPNVGPQQQQQQQQQQHAGLLGKGTPNALQQQLHMNQLTGIPPPGLMNNSDVHTSSNNNSRQLLDQLANGNANMLNMNMDNNNNNNNNNNNNNNNGGGSGVMMNASTAAVNSIGMVPTVGTPVNINVNASNPLLHPHLDDPSLLNNPIWKLQLHLAAVSAQSLGQPNIYARQNAMKKYLATQQAQQAQQQAQQQAQQQVPGPFGPGPQAAPPALQPTDFQQSHIAEASKSLVDCTKQALMEMADTLTDSKTAKKQQPTGDSTPSGTATNSAVSTPLTPKIELFANGKDEANQALLQHKKLSQYSIDEDDDIENRMVMPKDSKYDDQLWHALDLSNLQIFNISANIFKYDFLTRLYLNGNSLTELPAEIKNLSNLRVLDLSHNRLTSLPAELGSCFQLKYFYFFDNMVTTLPWEFGNLCNLQFLGVEGNPLEKQFLKILTEKS-VTGLIFYLRDNRPEIPLPHERRFIEINTDGEPQREYDSLQQSTEHLATDLAKRTFTVLSYNTLCQHYATPKMYRYTPSWALSWDYRRNKLKEQILSYDSDLLCLQEVESKTFEEYWVPLLDKHGYTGIFHAKARAKTMHSKDSKKVDGCCIFFKRDQFKLITKDAMDFSGAWMKHKKFQRTEDYLNRAMNKDNVALFLKLQH-------------IPSGDTIWAVTTHLHWDPKFNDVKTFQVGVLLDHLETLLKEETS----HNFRQDIKKFPVLICGDFNSYINSAVYELINTGRVQIHQEGNGRDFGYMSEKN--------------FSHNLALKSSYNCIGELPFTNFTPSFTDVIDYIWFSTHALRVRGLLGEVDPEYVS--KFIGFPNDKFPSDHIPLLARFEFMKTNTGSKKV-----------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:*. : : . : .. * *::: : .:*..:: .** *::*.* * .:*.:: * * *:** *:* *******. . *: : : :* : .**:*:*.* :* **: ****.::::.: : . . *: :: ** : . : * * : .* : : . ***:.**.**::*** ::* * ***** *:**:: : ::* :*::.***:*:: : :: *.. ** *:* .*:*** : . : * **** :**: .:* *: : ::*. * : : :: ***.* ***:.: *: : : . .:*:****:: *** :*. :: ..::.: .. : : . . :::*.*:** :*.* * :..* * . . : ::: * . ::*.: * *:*: :*.**:* .*..:****:::. : *:** :. ::: :. * *: ::****:.**..:* . ", "identical_positions": 143, "similar_positions": 189, "identity": "16.1%" }, { "cls_id": "homologset.agr.RGD:1309131", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4ACN6-1", "uniprot_id": "D4ACN6_RAT", "id": "D4ACN6-1", "name": "Ceramide transfer protein", "aln": "MQRSSFPVQLSPFPAPPPSLPVVTREGRRGPSSGGGAGRSAGVTATAADGWKGRLSSPLVLLPWSARCQARRRRRSGRASSLFLFPHSPERALLAVPSPDPSPQGLGACTGAARGAGAGLLLGCRVSMSDNQSWNSSGSEEDPETES---GPPVERCGVLSKWTNYIHGWQDRWVVLKNNTLSYYKSEDETEYGCRGSICLSKAVITPHDFDECRFDISVNDS-VWYLRAQDPDHRQQWVDAIEQHKTESGYGSESSLRRHGSMVSLVSGASGYSATSTSSFKKGHS-LREKLAEMETFRDILCRQVDTLQKYFDVCADAVSKDELQRDKVVEDDEDDFPTTRSDGDFLHN-TNGNKEKLFPHVTPKGINGIDFKGEAITFKATTAGILATLSHCIELMVKREESWQKRHDREVEKRRRVEEAYKNVTEELK--KKPRFGGPDYEEGPNSLINEEEFFDAVEAALDRQDKIEEQSQSEKVRLHWPPSLPSGDTFSSVGTHRFVQKPYSRSPSMSSIDLVSASDDVHRFSSQVEEMVQNHMNYSLQDVGGDAN-WQLVVEEGEMKVYRREVEENGIVLDPLKATHAVKGVTGHEVCNYFWNVDVRNDWETTIENFHVVETLADNAIIIYQTHKRVWPASQRDVLYLSAIRKIPALTENDP-ETWIVCNFSVDHDSAPLNN-RCVRAKINIALICQTLVSP-PEGDQEISRDNILCKITYVANVNPGGWAPASVLRAVAKREYPKFLKRFTSYVQEKTAGKPILF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EQG9-1", "uniprot_id": "CERT_MOUSE", "id": "Q9EQG9-1", "name": "Ceramide transfer protein", "aln": "-------------------------------------------------------------------------------------------------------------------------------MSDNQSWNSSGSEEDPETES---GPPVERCGVLSKWTNYIHGWQDRWVVLKNNTLSYYKSEDETEYGCRGSICLSKAVITPHDFDECRFDISVNDS-VWYLRAQDPEHRQQWVDAIEQHKTESGYGSESSLRRHGSMVSLVSGASGYSATSTSSFKKGHS-LREKLAEMETFRDILCRQVDTLQKYFDVCADAVSKDELQRDKVVEDDEDDFPTTRSDGDFLHN-TNGNKEKLFPHVTPKGINGIDFKGEAITFKATTAGILATLSHCIELMVKREESWQKRHDREVEKRRRVEEAYKNVMEELK--KKPRFGGPDYEEGPNSLINEEEFFDAVEAALDRQDKIEEQSQSEKVRLHWPTSLPSGDTFSSVGTHRFVQKPYSRSSSMSSIDLVSASDDVHRFSSQVEEMVQNHMNYSLQDVGGDAN-WQLVVEEGEMKVYRREVEENGIVLDPLKATHAVKGVTGHEVCNYFWNVDVRNDWETTIENFHVVETLADNAIIVYQTHKRVWPASQRDVLYLSAIRKIPALTENDP-ETWIVCNFSVDHDSAPLNN-RCVRAKINIAMICQTLVSP-PEGDQEISRDNILCKITYVANVNPGGWAPASVLRAVAKREYPKFLKRFTSYVQEKTAGKPILF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y5P4-1", "uniprot_id": "CERT_HUMAN", "id": "Q9Y5P4-1", "name": "Ceramide transfer protein", "aln": "-------------------------------------------------------------------------------------------------------------------------------MSDNQSWNSSGSEEDPETES---GPPVERCGVLSKWTNYIHGWQDRWVVLKNNALSYYKSEDETEYGCRGSICLSKAVITPHDFDECRFDISVNDS-VWYLRAQDPDHRQQWIDAIEQHKTESGYGSESSLRRHGSMVSLVSGASGYSATSTSSFKKGHS-LREKLAEMETFRDILCRQVDTLQKYFDACADAVSKDELQRDKVVEDDEDDFPTTRSDGDFLHS-TNGNKEKLFPHVTPKGINGIDFKGEAITFKATTAGILATLSHCIELMVKREDSWQKRLDKETEKKRRTEEAYKNAMTELK--KKSHFGGPDYEEGPNSLINEEEFFDAVEAALDRQDKIEEQSQSEKVRLHWPTSLPSGDAFSSVGTHRFVQKPYSRSSSMSSIDLVSASDDVHRFSSQVEEMVQNHMTYSLQDVGGDAN-WQLVVEEGEMKVYRREVEENGIVLDPLKATHAVKGVTGHEVCNYFWNVDVRNDWETTIENFHVVETLADNAIIIYQTHKRVWPASQRDVLYLSVIRKIPALTENDP-ETWIVCNFSVDHDSAPLNN-RCVRAKINVAMICQTLVSP-PEGNQEISRDNILCKITYVANVNPGGWAPASVLRAVAKREYPKFLKRFTSYVQEKTAGKPILF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5M7Y0-1", "uniprot_id": "CERT_DANRE", "id": "Q5M7Y0-1", "name": "Ceramide transfer protein", "aln": "-------------------------------------------------------------------------------------------------------------------------------MSDCS---SSGSDEDLDPES---ELLDELGGKLSKWTNYIHGWQDRWIALKGNILSYYRSADEKEYGCRGSICLSKAVITPHEFDECRFDISVNDS-IWYLRAEHPLLRQQWIDTIELHKAESGYGSESSLRRHGSLLSLTSAASGLSTASASSFKKAYS-LQEKLAEMETFRDILCRQVDTLQKYFDNCADNESKDELHRDKVS-DEEEDFPTLRPDADYLLNNNNSSKEKLFSVNTLKDPAGIDFKGEAITFKATTAGILSTLSHCIDILVKREESWQKRLDKEIERRRRAEDAYKAALTELK--KKPHYGGPDYEEGPNSLINEEEFFDAVEAALDKHDQIEEQSQVERSRASRQISLTP-DTFSSISTQKYLTKPHSHTSSLSSVDLISASDDVHRFSAQVEEMVHSHMTYSLQDVGGDAN-WQLVVEEGDMKVYRREVEENGIVLDPLKATHAVKGVTGHEVCHYFWDTAYRNDWETTVESFQVVETLSDQACIIHQTLKRVWPASQRDVLYVSVMRKILSTNENDP-DTWLVCNFSVDHDGYPPST-RCIRAKINVAMICQTLISP-PEGDKEISRDNIICKITYVANVNPGGWAPASVLRAVAKREYPKFLKRFTSYVEVKTSSEAILF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9Y128-1", "uniprot_id": "Q9Y128_DROME", "id": "Q9Y128-1", "name": "Ceramide transfer protein", "aln": "---------------------------------------------------------------------------------------------------------MDTNAGESLGASP---------PSSNEAAAGSQSQSDASEEEEYLDNSIELRGYLSKWTNYIYGWQPRYIVLKDGTLSYYKSESESDFGCRGAISLTKATIKAHESDELRFDVVVNNLNNWCLRAETSEDRMHWVDVLQLYKADSGSTDTTSLRRHGSTMSLQS--NTISLTSGGSLKKTQRNLREKVGELETFKDILFGQIETLQRYFDACS-----------------------------------EVNKNNAQPLDLGDGLKSIDFKGESITFRATTSGVLTTLQHCLEIIAESDESWKRKLEREIDKRRRSEDQSKKLKDEVEKMKRLSYPGPDFEEGPHSTLPEDEFFDAVETGLD---KIEEDMQ---LRFKLKLQSQISQTLVNVPHEAVAEGEEAREEFGTGAEATS-----HALWPEIDRVCKEQLHYAREGVGQDGNGWQIFADEGEIKMYKREEEVNGLVMDPLKAYHTVQGVTAREMCHYFFMPEFRNDWETTLEDCTILEKISADTLLFLQTHKRIWPASQRDAQFWSHMRKITDNLEPGARDMWVVCNNSTEYAKQESKNGKCVRIFLTVILACQTHLPEGYVKGQPLNRNDLTCKITYCSVVNPGGWAPASALRAVYKREYPKFLKRFTGYVIDQCKDKPIMF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. . .* *:.* . *. * * ********:*** *::.**.. ****:* .*.::****:*.*:**.*..*: ** ***: **: * ***: . * :*:*.:: :*::** . :******* :** * . * :* .*:** *:**:.*:***:*** *::***:*** *: : .*:: . .. .******:***:***:*:*:**.**::::.: ::**::: ::* :::** *: * *:: *: : ***:****:* : *:*******:.** :***: * * . ::: .: . :: :. : * * : .:::.: :.:: *: :.** *.* **:..:**::*:*:** * **:*:***** *:*:***.:*:*:**: *******:*. ::*.:: :: :. ** **:*******. : * :*** * .. : *:*** *.:: .. :*:* :.: : *** :. .: :.*::: ***** : **********.**** ************.** : .:.*:*", "identical_positions": 242, "similar_positions": 187, "identity": "31.72%" }, { "cls_id": "homologset.agr.RGD:1309132", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U2R5-1", "uniprot_id": "PPR3C_RAT", "id": "Q5U2R5-1", "name": "Protein phosphatase 1 regulatory subunit 3C", "aln": "-------------------------------------------------------------MSCTRMIHVLDPRPLTSSVMPVDMAMR-----------------------------------------------------------------------ICLAHSPPLKSFLGPYNGLQRRHFVN-KPKPLKPCLSVKQ-----------------------EAK-SQKEWKSPHSQ-----------AKKRVVFADSKGLSLTAIHVFSDLP----------------------------------------------------------------EEPAWDLQFDLLDLNDISSSLKLHEEKN-----------------------------LVFDFPQPSS-DYLSFRDRFQKNFVCLENCSLQDRT------------------------------------------VTGTVKVKNVSFEKKVQVRITFDTWKTYTDVDCVYLKN----VYGSSDSDTFSFAIDLPRVIPTEEK----IEFCISYHAN-----GRVFWDNNEAQNYRIVHVQWKPDGVQ--TQVAPKDCAFQQVPLKTELEPTVFG--SPRLASGLFPEWQSWGRVENLASYR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TMB3-1", "uniprot_id": "PPR3C_MOUSE", "id": "Q7TMB3-1", "name": "Protein phosphatase 1 regulatory subunit 3C", "aln": "-------------------------------------------------------------MSCTRMIHVLDPRPLTSSVMPVDMAMR-----------------------------------------------------------------------ICLAHSPPLKSFLGPYNGFQRRNFVN-KLKPLKPCLSVKQ-----------------------EAK-SQSEWKSPHNQ-----------AKKRVVFADSKGLSLTAIHVFSDLP----------------------------------------------------------------EEPAWDLQFDLLDLNDISSSLKLHEEKN-----------------------------LVFDFPQPST-DYLSFRDRFQKNFVCLENCSLQDRT------------------------------------------VTGTVKVKNVSFEKKVQVRITFDTWKTYTDVDCVYMKN----VYSSSDSDTFSFAIDLPRVIPTEEK----IEFCISYHAN-----GRIFWDNNEGQNYRIVHVQWKPDGVQ--TQVAPKDCAFQQGPPKTEIEPTVFG--SPRLASGLFPEWQSWGRVENLTSYR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UQK1-1", "uniprot_id": "PPR3C_HUMAN", "id": "Q9UQK1-1", "name": "Protein phosphatase 1 regulatory subunit 3C", "aln": "-------------------------------------------------------------MSCTRMIQVLDPRPLTSSVMPVDVAMR-----------------------------------------------------------------------LCLAHSPPVKSFLGPYDEFQRRHFVN-KLKPLKSCLNIKH-----------------------KAK-SQNDWKCSHNQ-----------AKKRVVFADSKGLSLTAIHVFSDLP----------------------------------------------------------------EEPAWDLQFDLLDLNDISSALKHHEEKN-----------------------------LILDFPQPST-DYLSFRSHFQKNFVCLENCSLQERT------------------------------------------VTGTVKVKNVSFEKKVQIRITFDSWKNYTDVDCVYMKN----VYGGTDSDTFSFAIDLPPVIPTEQK----IEFCISYHAN-----GQVFWDNNDGQNYRIVHVQWKPDGVQ--TQMAPQDCAFHQTSPKTELESTIFG--SPRLASGLFPEWQSWGRMENLASYR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QTC2-1", "uniprot_id": "F1QTC2_DANRE", "id": "F1QTC2-1", "name": "Protein phosphatase 1 regulatory subunit 3C", "aln": "-------------------------------------------------------------MSSTRVLHILSP-PMPGPVMPVDVAVQ-----------------------------------------------------------------------LYITHSPPLRNFLSSYEDYRTRNLVSNCCKPLRPCLSSRA-----------------------QLEHSCRSWQNPKSK-----------TKKKVVFADSKGMSLTAVHVFSTFDNK--------------------------------------------------------------ETATSELQFDLEDLEELKNTLHINSVQS-----------------------------RILDFLQPAA-DYLDFRSHLLKNLVCLENCTLQERA------------------------------------------LTGTIKVRNLAYEKSVHVRITFDSWKSFEDIECTFMNN----VYGCQDTDTFSFAIELPGYVPPQNK----VEFCISFRTG-----EQIYWDNNDGRNYGLISTSWQQNNKLNSSTQTKKSDEFRKKSSKKTQEKGVFKCKSSLQSNGIFPNWQSWGQIAATGPYW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6P950-1", "uniprot_id": "PR3CB_DANRE", "id": "Q6P950-1", "name": "Protein phosphatase 1 regulatory subunit 3C-B", "aln": "-------------------------------------------------------------MNCTRVLQILNPRPMPSPIMPVDVAMR-----------------------------------------------------------------------ICLAHSPPLRSFLSSYEDCKSRNLVN-QYKPLRSCISSKT-----------------------EDDTANITWKSPETK-----------AKKKVVFADSKGMSLTAVHVFKEFE----------------------------------------------------------------EDLMLDLQFELSDLEDAIVGLKAEKEKN-----------------------------FSLGFPQPAA-DYLDFRNRLKKNLVCLENCIIQERS------------------------------------------VTGTVKVSNVSFEKVVHVRITFDSWKSHTDIPCTYMNN----VYGCEDVDTFSFSIDLPSFVAPHEQ----VEFCLSYKTH-----DMTYWDNNDGKNYKLVHT---ENDSSQASVIQNATTDFKAQGKRPDMEFDQFG--SPRTSSGFFPEWQSWGHIENNTPYW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VUF3-1", "uniprot_id": "Q9VUF3_DROME", "id": "Q9VUF3-1", "name": "Protein phosphatase 1 regulatory subunit", "aln": "-----MISHSPPIFSHSPPVSFLADFMSGHPRQSLNYNDEPNRASRYCRPQVITLASKAMVNNASAAVQGQGPSQQKAGATPLGVGSRSGRSY-----------------------------------------------------------------LERMASAPLLTNQPKSCLSRKSCLHKSQNTTASSADLSPTD-----------------------TDVADSASHSCICSKDSDSNGEVSRGPKKHVIFADDEGLSLTEVRVMSEPS-------------------------------------------------------------------NVPPYWSMKFLEQITQGLVSPHPPDQ----------------------------WTVDFKQPAS-DYLSFRQKIERDFVSLENVIVKDEES----------------------------------------IVVGTIKVKNIDFQKEIIVRVTWDDWKSQQDIFCTYARAYGPATCAHVVFDTFSFKITLP---PSSKR----LEFCICYRTN-----ETEYWDNNDGKNYTISKRSPFYYNALSPYDKGQNRNSSQQIRSTLTDALAKVQD-------------QNGWHQEPHTPYW", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40036-1", "uniprot_id": "GIP2_YEAST", "id": "P40036-1", "name": "GLC7-interacting protein 2", "aln": "MYIKAEQKPQQFERKNEKLDRNKNQQLPDLETDFKGYRVNSDLYNKERDGSTEETLNSLKFLHKPQRVTQMRANRFPEEEVQRNTDLNKRIFSAGNDENVDNESGWSKIAAAKNHTSVESLNGSTRPPFKIELPPLSPKSTVPKSFQAEYPEAKSPGNDMNFEYDEEILIPFAPPVYKKSGELLKSSLKRRSKSLPTTP-------GIRSGNGVQARDGSPMLIRSKSVHFDQAAPVKYFAEDESPINVNKTEQHDNCLSFKHKPVNLMVDPEEE------TKMLSSG------------------LETTSIDDDLTTVAPKGFAHPAKISNPNNGKGTNNTKLRKSKRFQNLLKNRTDMPPSKSNKKFVNGGGAHEISDR---NSKNYHVVGLYSKNFPILSNKNPKSLKLNIFINLSQNKKVFLQELSLYIHRDNNYFSNSSSFYNIPNSHNGNDCNGVAKGYNAGCTRLIAGRILVKNIFYDKRVVVRYTWDSWRTTHEVECVYISD-GDGILPGTNMDIFHFIIDDVSKVDPR----GKLEFCIHYSTR-NDYEREEYWDNNNGNNYKVDVVMDG--------FNDPFAAAA------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P40187-1", "uniprot_id": "PIG2_YEAST", "id": "P40187-1", "name": "GSY2-interacting protein PIG2", "aln": "---MATTTQPQNILMDEPLNLPNN---SAHNNNYGNINANIRTFAGMSMHMHPARLNSLEFLHKPRRLSNVKLHRLPQDELQRNTDMNKGMYFNGKQVHAHHPFINSGANFNAHHQDVSKLG--------------------------EEEDEISPLSHDNFQYESEENGNPSPPIYKKSGELVKSSLKRRSKSLPITPKSIFNKTGSKSKHVNLDHVDTRLLQRSKSVHFDRVLPIKLFNENEKPIDVGKQMVQQDVLNFKHKPLTRLSALNGGSDSVPIEDLLSENNQNEYGDTWLQNPKGVFLFGTNSNNRRNKKKKFKLSDDDSDIENDNDSDDAINRLVRQQDKDQAHLAHGLKNLLINDDDDYLETRTNSAKSGANLFIGNSKRIVGLYNKNFPILSDRNRKSLKLNIFLNLSRGRPVFLQEITLLTGFHN---------------------------------MVIIGKVFVKNIYFDKKIIVRYTWDAWRTFHESECVYFSN-ANGILPGSNMDIFKFSIDDIHNPNDKDSNISQLEFCIQYLTWGVDRSRKEYWDNNDSANYKIDVVTNETRTGPTTDVNDNYEMKHSLFRNPFH----------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . . : . : . . : . * : .:. . : : . . .* : : .:: .: :: . ::: : * : * *: ::* : :* *:* *:. : *.: * * * * :***: : : :****:. ** : ", "identical_positions": 24, "similar_positions": 55, "identity": "3.76%" }, { "cls_id": "homologset.agr.RGD:1309133", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5YBE4-1", "uniprot_id": "A0A8I5YBE4_RAT", "id": "A0A8I5YBE4-1", "name": "Plakophilin-3", "aln": "MQEGNFLLSALQPEAGVCSLALPSDLQLDRRGAEGPEADRLRAARVQEQVRARLLQLGQQSRHNGSTELDGSAESTRGLPRGQYHTMQSGFSSRSQGMSGDKTSTFRPIAKPAYNPASWSSRSAVDLTCSRRLSSAHNGGSAFGAVGYGGAQPTPPMPTRPVSFHERGGAASRADYDTLSLRSLRLGPGGLDDRYSVVSEQLEPAAASTYRAYAYERQASSSSSRAGGLDWPEATEGPPSRTIRAPAMRTLQRFQSSHRSRGGTGSVSGAGLEPVARAPSVRSLSLSLGDSGHLPDVRGLDSYTGHRTLQRLSSGFDDIDLPSAVKYLMASDPNLQVLGAAYIQHRCYSDAAAKKQARSLQAVPRLVKLFNHANQEVQRHATGAMRNLIYDNVDNKLALVEENGIFELLRTLREQDDELRKNVTGILWNLSSSDHLKDRLARDTLEQLTDLVLSPLSGAGGPPLIQQNASEAEIFYNATGFLRNLSSASQATRQKMRECHGLVDALVTYINHALDVGKCEDKSVENAVCVLRNLSYRLYDEMPPSALQRLEGRGRRDMAGAPPGEVVGCFTPQSRRLRELPLTADALTFAEVSKDPKGLEWLWSPQIVGLYNRLLQRCELNRHTTEAAAGALQNITAGDRRWAGVLSRLALEQERILNPLLDRVRTADHNQLRSLTGLIRNLSRNARNKDEMSTKVVSHLIEKLPGSVGEKCPPAEVLVNIIAVLNNLVVASPIAARDLLYFDGLRKLVFIKKKRDSPDSEKSSRAASSLLANLWQYSKLHRDFRAKGYRKEDFLGP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QY23-1", "uniprot_id": "PKP3_MOUSE", "id": "Q9QY23-1", "name": "Plakophilin-3", "aln": "MQEGNFLLSALQPETGVCSLALPSDLQLDRRGAEGPEADRLRAARVQEQVRARLLQLGQQSRHNGSAELDGSAESARGMPRGQYHTMQTGFSSRSQGMSGDKTSTFRPIAKPAYSPASWSSRSAVDLTCSRRLSSAHNGGSAFGAVGYGGTQPTPPMPTRPVSFHERGGAASRADYDTLSLRSLRLGPGGLDDRYSVVSEQLEPAAASTYRAYAYERQASSGSSRAGGLDWPEATEGPPSRTIRAPAMRTLQRFQSSHRSRGGTGSVSGAGLEPVARAPSVRSLSLSLADSGHLPDVRGLDSYTGHRTLQRLSSGFDDIDLPSAVKYLMASDPNLQVLGAAYIQHRCYSDAAAKKQARSLQAVPRLVKLFNHANQEVQRHATGAMRNLIYDNVDNKLALVEENGIFELLRTLREQDDELRKNVTGILWNLSSSDHLKDRLARDTLEQLTDLVLSPLSGAGGPPLIQQNASEAEIFYNATGFLRNLSSASQATRQKMRECHGLVDALVTYINHALDVGKCEDKSVENAVCVLRNLSYRLYDEMPPSALQRLEGRGRRDMAGAPPGEMVGCFTPQSRRLRELPLTADALTFAEVSKDPKGLEWLWSPQIVGLYNRLLQRCELNRHTTEAAAGALQNITAGDRRWAGVLSRLALEQERILNPLLDRVRTADHNQLRSLTGLIRNLSRNARNKDEMSTKVVSHLIEKLPGSVGEKCPPAEVLVNIIAVLNNLVVASPIAARDLLYFDGLRKLVFIKKKRDSPDSEKSSRAASSLLANLWQYSKLHRDFRAKGYRKEDFLGP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y446-1", "uniprot_id": "PKP3_HUMAN", "id": "Q9Y446-1", "name": "Plakophilin-3", "aln": "MQDGNFLLSALQPEAGVCSLALPSDLQLDRRGAEGPEAERLRAARVQEQVRARLLQLGQQPRHNGAAEPEPEAETARGTSRGQYHTLQAGFSSRSQGLSGDKTSGFRPIAKPAYSPASWSSRSAVDLSCSRRLSSAHNGGSAFGAAGYGGAQPTPPMPTRPVSFHERGGVGSRADYDTLSLRSLRLGPGGLDDRYSLVSEQLEPAATSTYRAFAYERQASSSSSRAGGLDWPEATEVSPSRTIRAPAVRTLQRFQSSHRSRGVGGAVPGAVLEPVARAPSVRSLSLSLADSGHLPDVHGFNSYGSHRTLQRLSSGFDDIDLPSAVKYLMASDPNLQVLGAAYIQHKCYSDAAAKKQARSLQAVPRLVKLFNHANQEVQRHATGAMRNLIYDNADNKLALVEENGIFELLRTLREQDDELRKNVTGILWNLSSSDHLKDRLARDTLEQLTDLVLSPLSGAGGPPLIQQNASEAEIFYNATGFLRNLSSASQATRQKMRECHGLVDALVTSINHALDAGKCEDKSVENAVCVLRNLSYRLYDEMPPSALQRLEGRGRRDLAGAPPGEVVGCFTPQSRRLRELPLAADALTFAEVSKDPKGLEWLWSPQIVGLYNRLLQRCELNRHTTEAAAGALQNITAGDRRWAGVLSRLALEQERILNPLLDRVRTADHHQLRSLTGLIRNLSRNARNKDEMSTKVVSHLIEKLPGSVGEKSPPAEVLVNIIAVLNNLVVASPIAARDLLYFDGLRKLIFIKKKRDSPDSEKSSRAASSLLANLWQYNKLHRDFRAKGYRKEDFLGP", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:***********:***********************:*********************.****::* : .**::** .******:*:********:****** *********.************:*****************.****:******************..*************************:*********:*****:********.************** .*********:************** *:*.** *****************.********:*::** .****************************************:**********************************************.******************************************************************************************************************* ******.*****************************************:*******:****************:**************************************************************************************:*****************************************.************************************:****************************.*******************", "identical_positions": 744, "similar_positions": 43, "identity": "93.35%" }, { "cls_id": "homologset.agr.RGD:1309134", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AHB5-1", "uniprot_id": "A0A8I6AHB5_RAT", "id": "A0A8I6AHB5-1", "name": "BBSome complex member BBS4", "aln": "MSLERYSFRRCTLACSDSVDLFHLLGSTEMPMKTQVPASIESQKPRPKKAPEFPIVEKLNWLIHLYYIRKDYEACKAVIKEQLQETQGLCEYAIYVQALIFRLEGNIQESLELFQTCAVLSPQCADNLKQVARSLFLLGKHKAATEVYNEAAKLN-QKDWEICHNLGVCYT-----------YLKQFSKAQDQLHSALQLNKHDLTYIMLGKIHLLQGDLDKAIEIYKKAVEFSPENTELLTTLGLLYLQLGVYQKAFEHLGNALTYDPAN-YKAILAAGSMMQTHGDFDVALTKYRVVACAIPESPPLWNNIGMCFFGKKKYVAAISCLKRANYLAPFDWKILYNLGLVHLTMQQYASAFHFLSAAINFQPKMGELYMLLAVALTNLEDIENAKRAYVEAVRLDK------CNPLVNLNYAVLLYNQGEKKGALAQYQEMEKKVHFLKDNNPLEFDSEMVEMAQKLGAALQVGEALVWTKPVKDPKSKHRTNSGSKSATLQQPLGSFQALGQAMSSAAAHRKIPSGAVG-AQLTKPPSLPLEPEPEPTVEASPTEASEQNKEK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C1Z7-1", "uniprot_id": "BBS4_MOUSE", "id": "Q8C1Z7-1", "name": "BBSome complex member BBS4", "aln": "------------------------MAEVKLGMKTQVPASVESQKPRSKKAPDFPIVEKQNWLIHLHYIRKDYEACKAVIKEQLQETQGLCEYAIYVQALIFRLEGNIQESLELFQTCAVLSPQCADNLKQVARSLFLLGKHKAATEVYNEAAKLN-QKDWEICHNLGVCYT-----------YLKQFNKAQDQLHSALQLNKHDLTYIMLGKIHLLQGDLDKAIEIYKKAVEFSPENTELLTTLGLLYLQLGVYQKAFEHLGNALTYDPAN-YKAILAAGSMMQTHGDFDVALTKYRVVACAIPESPPLWNNIGMCFFGKKKYVAAISCLKRANYLAPFDWKILYNLGLVHLTMQQYASAFHFLSAAINFQPKMGELYMLLAVALTNLEDIENARRAYVEAVRLDK------CNPLVNLNYAVLLYNQGEKKSALAQYQEMEKKVNFLKDNSPLEFDSEMVEMAQKLGAALQVGEALVWTKPVKDPKTKHRTNSGSKSATLQQPLGSIQALGQAMSSAAAYRKILSGAVG-AQLPKPPSLPLEPEPEPTVEASPTEASEQKKEK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96RK4-1", "uniprot_id": "BBS4_HUMAN", "id": "Q96RK4-1", "name": "BBSome complex member BBS4", "aln": "------------------------MAEERVATRTQFPVSTESQKPRQKKAPEFPILEKQNWLIHLHYIRKDYEACKAVIKEQLQETQGLCEYAIYVQALIFRLEGNIQESLELFQTCAVLSPQSADNLKQVARSLFLLGKHKAAIEVYNEAAKLN-QKDWEISHNLGVCYI-----------YLKQFNKAQDQLHNALNLNRHDLTYIMLGKIHLLEGDLDKAIEVYKKAVEFSPENTELLTTLGLLYLQLGIYQKAFEHLGNALTYDPTN-YKAILAAGSMMQTHGDFDVALTKYRVVACAVPESPPLWNNIGMCFFGKKKYVAAISCLKRANYLAPFDWKILYNLGLVHLTMQQYASAFHFLSAAINFQPKMGELYMLLAVALTNLEDIENAKRAYAEAVHLDK------CNPLVNLNYAVLLYNQGEKKNALAQYQEMEKKVSLLKDNSSLEFDSEMVEMAQKLGAALQVGEALVWTKPVKDPKSKHQTTSTSKPASFQQPLGSNQALGQAMSSAAAYRTLPSGAGGTSQFTKPPSLPLEPE--PAVESSPTETSEQIREK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1Z8E9-1", "uniprot_id": "BBS4_DROME", "id": "A1Z8E9-1", "name": "BBSome complex member BBS4 homolog", "aln": "---------------------MYEPGTEQINCNGRLIELPTLEVVRP--APKMPSDANIDWLLHIYFTRREFTRCRRLIERELNRHLNP-EYLYFVQGLIDREEGNHIEALRHLQKSAELNPRNIETYKEIGRTLYIMGRFSQALGVFREAEQRSSRQDHEIYHYLGELLYRAATTQSQKDVASQQQDEARTYFELAVQSGRKLESYVRLAELYRKDKQYQKAIEILENCLHLTPENSEVLIEISVLYLKINETQKAHDRLAEVVSIERKCSPKGLLAFGAILQSRNDIDGALSKYSQIANAEPEIAELWNNIGLCFFKKQKFIVAISSLRKSVWLSPLNYNALYNLSLIYIASEQYASAFHTLAAAINLRKDNAECYMLLGLCLRKLDDMENAFVALERASSMATGQQGAGRNPLVVLNFALFCYETGRLALSTEQYNRFMSQAQDLLLPTEYKFQATKLKSLLRISNQGNG----ILLDSADMGESDLGHNRATELLPDELPLEVNAVVSQN--------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .: . :. : * **.:* : :**:*::: *::: *: :*:.:*:. . ** :**.** * *** *:*. :*..* *.*: :. *::.*:*:::*:.. * *:.** : . ::* ** * ** :* .:*: :. *:: .:: :*: *.::: : : :****: ::.:.::***:*:* :.:***::. ***.::*.:.:: : *.:** *:::*::.*:* **:** :* * ** . ******:*** *:*::.***.*::: :*:*:::: ****.*:::: :******* *:****:: . .* ****.:.* :*:*:*** * .* : . **** **:*:: *: *. : **:.: .:. * . :*:: :: ::. : : .... ::. . :: . : ** .:.* ", "identical_positions": 140, "similar_positions": 183, "identity": "24.82%" }, { "cls_id": "homologset.agr.RGD:1309135", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U1Z2-1", "uniprot_id": "TPPC3_RAT", "id": "Q5U1Z2-1", "name": "Trafficking protein particle complex subunit 3", "aln": "-MSRQANRGTESK----------KMSSELFTLTYGALVTQLCKDYEND-EDVNKQLDRMGYNIGVRLIEDFLARSNVGRCHDFRETADVIAKVAFKMYLGITPSITNWSPAGDEFSLILENNPLVDFVELPDN-HSALIYSNLLCGVLRGALEMVQMAVEAKFVQDTLKGDGVTEIRMRFIRRIEDNLPAGEE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O55013-1", "uniprot_id": "TPPC3_MOUSE", "id": "O55013-1", "name": "Trafficking protein particle complex subunit 3", "aln": "-MSRQANRGTESK----------KMSSELFTLTYGALVTQLCKDYEND-EDVNKQLDRMGYNIGVRLIEDFLARSNVGRCHDFRETADVIAKVAFKMYLGITPSITNWSPAGDEFSLILENNPLVDFVELPDN-HSALIYSNLLCGVLRGALEMVQMAVEAKFVQDTLKGDGVTEIRMRFIRRIEDNLPAGEE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43617-1", "uniprot_id": "TPPC3_HUMAN", "id": "O43617-1", "name": "Trafficking protein particle complex subunit 3", "aln": "-MSRQANRGTESK----------KMSSELFTLTYGALVTQLCKDYEND-EDVNKQLDKMGFNIGVRLIEDFLARSNVGRCHDFRETADVIAKVAFKMYLGITPSITNWSPAGDEFSLILENNPLVDFVELPDN-HSSLIYSNLLCGVLRGALEMVQMAVEAKFVQDTLKGDGVTEIRMRFIRRIEDNLPAGEE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VSY8-1", "uniprot_id": "Q9VSY8_DROME", "id": "Q9VSY8-1", "name": "Trafficking protein particle complex subunit", "aln": "-MSRQASR-LDAK----------KVNSEFLTLTYGALVTQMLRDFENA-EDVNKQLERIGYNMGMRLIEDFLARTSAPRCLEMRETADRIQQ-AFRIYLNIQPTISNWSPASDEFSLVFDSNPLTEFVELPPD-LTNLRYSAILSGCIRGALEMVQLEVQCWFVQDQLKGDNVTELRVKFVRRLEEVIPAGED", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36149-1", "uniprot_id": "BET3_YEAST", "id": "P36149-1", "name": "Trafficking protein particle complex subunit BET3", "aln": "MVSTTQSRSLKAMGEEIWKNKTEKINTELFTLTYGSIVAQLCQDYERDFNKVNDHLYSMGYNIGCRLIEDFLARTALPRCENLVKTSEVLSKCAFKIFLNITPNITNWSHNKDTFSLILDENPLADFVELPMDAMKSLWYSNILCGVLKGSLEMVQLDCDVWFVSDILRGDSQTEIKVKLNRILKDEIPIGED", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* .* .: *:.:*::*****::*:*: :*:*. :.**.:* :*:*:* *********: ** :: :*:: : : **:::*.* *.*:*** * ***:::.***.:***** : . * ** :*.* ::*:*****: : **.* *:**. **::::: * ::: :* **:", "identical_positions": 75, "similar_positions": 65, "identity": "38.86%" }, { "cls_id": "homologset.agr.RGD:1309139", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZNI7-1", "uniprot_id": "D3ZNI7_RAT", "id": "D3ZNI7-1", "name": "", "aln": "-----MPHSQESYPNPAVGDKDTHLGNLLAS-KKSTFKNPTHLVQQQDTWNRLSSASTATSIR-RDAYFYDPKIPKDDLDFRLAALYDHHTGAFKNKTEILLHQETIEDMQGTKLQFPGECFHSPSAPITSRTTIRHWINPK-------------KESIHSIQGSIVSP--HTAATNGGYSRKN-DGGFFST", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DAD0-1", "uniprot_id": "CF276_MOUSE", "id": "Q9DAD0-1", "name": "Cilia- and flagella-associated protein 276", "aln": "-----MLQPQETFSNPALRDEDKHLGNLWAS-KKSLYKNPAHLAQQQDPWSRLSSTPTATSRS-RDT-FFDSKIPKDDLDFRLATLYNHHTGAFKNKTEILLHQETIEDIQGTKIQFPGECFHAPSAPITSRTTIRHWINPK-------------KESIHSIQGSIVSP--HTAATNGGYSRKN-DGGFFST", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5T5A4-1", "uniprot_id": "CF276_HUMAN", "id": "Q5T5A4-1", "name": "Cilia- and flagella-associated protein 276", "aln": "-----MPPTRDPFQQPTLDNDDSYLGELRAS-KKLPYKNPTHLAQQQEPWSRLNSTPTITSMR-RDAYYFDPEIPKDDLDFRLAALYNHHTGTFKNKSEILLNQKTTQDTYRTKIQFPGEFLTPPTPPITFLANIRHWINPK-------------KESIHSIQGSIVSP--HTAATNGGYSRKK-DGGFFST", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8Y5T1-1", "uniprot_id": "CF276_DANRE", "id": "A8Y5T1-1", "name": "Protein CFAP276", "aln": "-----MPQERDPFPFPRYEN-DFTLTGRKEI-QKLSDDKPTHLAQNDEPWRRLHNTTTEASSR-RTVFHYDTTTPKDSLDIHLKAAYDHHLGLFQNKSQTVMQMETVGADNGTKKNKE---LEDSVCDAENKG-IKVWVDTQ-------------KASLYSIKGSIESH--HTASTNRGYSRKH-DGGFYST", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VK88-1", "uniprot_id": "Q9VK88_DROME", "id": "Q9VK88-1", "name": "", "aln": "MIQYDTVQIKNVSWQPELHTEGTYVCSFPEPPLPEAHLKPGTWHGHLEPYQRLFYHQTMNSVRSSKRYRANPNIPKDTLDFSLQSRYDHTREAFPDKVDYVMQRETCRAISSWSAPGAAKEIGSQLKSFRVLRNTRFIRRKQEDVLGHPLRIGGCKEKIHPHSVKLICSGVHNQLVNNGFSRQTSDGNFFRY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: * . : :* : :.: ** * * :. *** **: * : *:* * :* : ::: :* . : : : * .::. . .: . *. .* *:**: **.*: ", "identical_positions": 26, "similar_positions": 38, "identity": "13.54%" }, { "cls_id": "homologset.agr.RGD:1309140", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q99JR6-1", "uniprot_id": "NMNA3_MOUSE", "id": "Q99JR6-1", "name": "Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------MKNRIP-VVLLACGSFNPITNMHLRLFEVARDHLHQTGRYQVIEGIISPVNDSYGKKDLVASHHRVAMARLALQ-TSDWIRVDPWESEQAQWMETVKVLRHHHRELLRSSAQMDGPDPSKTP-SASAALP----------ELKLLCGADVLKTFQTPNLWKDTHIQEIVEKFGLVCVSRSGHDPERYISDSPILQQFQHNIHLAREPVLNEISATYVRKALGQGQSVKYLLPEAVITYIRDQGLYINDGSWKGK----------------GKTG------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7F588-1", "uniprot_id": "F7F588_RAT", "id": "F7F588-1", "name": "Nicotinamide-nucleotide adenylyltransferase", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------MKNRIP-VVLLACGSFNPITNMHLRLFEVARDHLHQTGKYQVIEGIISPVNDSYGKKDLVASHHRVAMARLALQ-TSDWIRVDPWESEQAQWMETVKVLRHHHGELLRSVAQMDGPDPSKIP-SASAALP----------ELKLLCGADVLKTFHTPNLWKDSHIQEIVEKFGLVCVNRSGHDPKRYILDSPILQQFQHNIHLAREPVLNEISATYVRKALSQGQSVKYLLPEAVITYIRDQGLYINDSSGKGK----------------GKTG------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96T66-1", "uniprot_id": "NMNA3_HUMAN", "id": "Q96T66-1", "name": "Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------MKSRIP-VVLLACGSFNPITNMHLRMFEVARDHLHQTGMYQVIQGIISPVNDTYGKKDLAASHHRVAMARLALQ-TSDWIRVDPWESEQAQWMETVKVLRHHHSKLLRSPPQMEGPDHGKALFSTPAAVP----------ELKLLCGADVLKTFQTPNLWKDAHIQEIVEKFGLVCVGRVGHDPKGYIAESPILRMHQHNIHLAKEPVQNEISATYIRRALGQGQSVKYLIPDAVITYIKDHGLYTKGSTWKGKSTQS----------TEGKTS------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VC03-1", "uniprot_id": "NMNA_DROME", "id": "Q9VC03-1", "name": "Nicotinamide-nucleotide adenylyltransferase", "aln": "-------------------------------------------------------------------------------------------------------------------------MIVKISWPKNNITSECFRRFGSFKRRSKSKKMSAFIEETKSLLPRIAFIACGCFSPPTPMHLRMFEIAKDHFEMQGTHRVVGGIISPTHDSYGKKGLASALDRCAMVKLATQ-SSNWIRLSDWEVHQNQWMRTQAVLQHHQNYINNHINSGGGGGDDGENTHLPGWLPRGLHDSRDPVHLKLLCGADLLESFAVPGLWAEADIEDIVANHGLVVITRAGSNPGKFIFDSDILTKYQSNITLITNWVPNEVSSTLIRRLLGRGQSVKYLLDDLVLEYIKRQRLFNFKSKYITDAVRPNHLLFNHAYTDNNKNANSYSIGDQLEQDMDESDTPSPQLQHTPTSRVFCCGEVPLRGSKVLRSGPGQAVQVITMQADEKEESQAKKQKISQVQL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06178-1", "uniprot_id": "NMA1_YEAST", "id": "Q06178-1", "name": "Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1", "aln": "MDPTRAPDFKPPSADEELIPPPDPESKIPKSIPIIPYVLADANSSIDAPFNIKRKKKHPKHHHHHHHSRKEGNDKKHQHIPLNQDDFQPLSAEVSSEDDDADFRSKERYGSDSTTESETRGVQKYQIADLEEVPHGIVRQARTLEDYEFPSHRLSKKLLDPNKLP-LVIVACGSFSPITYLHLRMFEMALDAISEQTRFEVIGGYYSPVSDNYQKQGLAPSYHRVRMCELACERTSSWLMVDAWESLQPSYTRTAKVLDHFNHEINIKRGGVATVTGEKIG-----------------VKIMLLAGGDLIESMGEPNVWADADLHHILGNYGCLIVERTGSDVRSFLLSHDIMYEHRRNILIIKQLIYNDISSTKVRLFIRRAMSVQYLLPNSVIRYIQEHRLYVDQTEPVKQVLG-------------NKE-------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P53204-1", "uniprot_id": "NMA2_YEAST", "id": "P53204-1", "name": "Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2", "aln": "MDPTKAPDFKPPQPNEELQPPPDPTHTIPKSGPIVPYVLADYNSSIDAPFNLDIYKTLSSRKKNANSS------NRMDHIPLNTSDFQPLSRDVSSEEESEGQSNGIDATLQDVTMTGNLGVLKSQIADLEEVPHTIVRQARTIEDYEFPVHRLTKKLQDPEKLP-LIIVACGSFSPITYLHLRMFEMALDDINEQTRFEVVGGYFSPVSDNYQKRGLAPAYHRVRMCELACERTSSWLMVDAWESLQSSYTRTAKVLDHFNHEINIKRGGIMTVDGEKMG-----------------VKIMLLAGGDLIESMGEPHVWADSDLHHILGNYGCLIVERTGSDVRSFLLSHDIMYEHRRNILIIKQLIYNDISSTKVRLFIRRGMSVQYLLPNSVIRYIQEYNLYINQSEPVKQVLD-------------SKE-------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :* : ::***.*.* * :***:**:* * : ..*: * **. *.* *:.*..: .* * .** : :*.*: :. ** * .: .* ** *.: : .: **.*.*::::: * :* ::.:..*: :.* : : * * : :: . *: .: ** : : : *::*:* :* : :. **:**: : *: **: *: . .* ", "identical_positions": 61, "similar_positions": 81, "identity": "11.94%" }, { "cls_id": "homologset.agr.RGD:1309141", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A2A716-1", "uniprot_id": "A2A716_MOUSE", "id": "A2A716-1", "name": "Oxysterol-binding protein", "aln": "MDFQER-DTPSLAESTQSS----KPSSTQQAS-----------ELWEVMEEPRG--RLGADDIMPERQ----EGHLLKKRKWPLKGWHKRYFVLEDGILHYATTRQDIT-------KGKVHGSIDVRLSVMSIN---KKAQRIDLDTEDNIYH--LKIKSQDLFHSWVAQLRAHRLAQRLDMP-----------------------SATHRKAPGTQMLTAGSAS--ALPGVGPRE--KVSSWLRDSDGLDRCSHALSECQGKLQELHR--LLQSLESLHRIPSAP----VIPTHQTSVTTERPKKGKRTSRMWCTQGFAKDDTIGRVGR----------------LHGSVPNLSRYLESRDTSGPRG----------------LPPPDYAHLQRSFWALAQKVHNS----LSSVLVALTTERDRLRDLHQGSELSR-------------------MVVSEAPDGQRRLHSLSISSDTTADSFSSLNPEEQEALYMKGRELTPQLSQS--SVLSLADSHTEFFDACEVLLS-----------------------------------ASSSENEGSEEEESCASEITTSLSEEVLDIRGADR-------------------YQKGPCVPGIAVGPPRRRCLPAASGPGTDVSLWNILRNNIGKDLSKVSMPVQLNEPLNTLQRLCEELEYSSLLDQASRMADPCERMVYIAAFAVSAYSSTYHRAGCKPFNPVLGETYECERPDRGFRFISEQVSHHPPISACHAESENFIFWQDMKWKNKFWGKSLEIVPVGTVNVSLPRFGDHFEWNKVTSCIHNILSGQRWIEHYGEVLIRNTQDSSCHCKITFCKAKYWSSN--IHEVQGAVLSRSGRVLHRLFGKWHEGLYRGPPPGGQCIWKPNSMPPDHERNFGFTQFALELNELTSELKRTLPSTDTRLRPDQRYLEEGNIQAAEAQKRRIEQLQRDRRRVMEENNIVHQARFFRRQTDSSGKEWWVTNHTYWRLRAEPGYGNLDGAVLW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0L2K0-1", "uniprot_id": "A0ABK0L2K0_RAT", "id": "A0ABK0L2K0-1", "name": "Oxysterol-binding protein", "aln": "MDFQER-DTPSLAESTQSS----KPSSTQQAS-----------ELWEVVEEPRG--RLGAEDIMPERQ----EGHLLKKRKWPLKGWHKRYFVLEDGVLHYATTRQDIT-------KGKVHGSIDVRLSVMSIN---KKAQRIDLDTEDNIYH--LKIKSQDLFQSWVSQLRAHRLAQRSDLP-----------------------NATHRKAPGTQTLTAGSAS--ALPGVGPRE--KVSSWLRDSDGLDRCSHALSECQGKLQELHR--LLQSLESLHRIPSAP----VIPTHQASVTTERPKKGKRTSRMWCTQGFAKDDTIGRVGR----------------LHGSVPNLSRYLESRDTSGPRG----------------LPPPDYAHLQRSFWALAQKVHNS----LSSVLVALTTERDRLRDLHQGSELSR-------------------MAVSEAPDGQRRLHSLSISSDTTADSFSSLNPEEQEALYRKGRELTPQLSQS--SVLSLADSHTEFFDACEVLLS-----------------------------------ASSSENEGSEEEESCASEITTSLSEEVLDIRGADR-------------------YPKGACVPGIAVGPPRRRCLPAASGPGTDVSLWNILRNNIGKDLSKVSMPVQLNEPLNTLQRLCEELEYSSLLDQASRMADPCERMVYIAAFAVSAYSSTYHRAGCKPFNPVLGETYECERPDRGFRFISEQVSHHPPISACHAESENFIFWQDMKWKNKFWGKSLEIVPVGTVNVSLPRFGDHFEWNKVTSCIHNILSGQRWIEHYGEVLIRNTQDSSCHCKITFCKAKYWSSN--IHEVQGAVLSRSGRVLHRLFGKWHEGLYRGPPPGGQCIWKPNSMPPDHERNFGFTQFALELNELTAELKRTLPSTDTRLRPDQRYLEEGNIQAAEAQKRRIEQLQRDRRRVMEENNIVHQARFFRRQTDSSGKEWWVTNHTYWRLRAEPGYGNLDGAVLW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BZF2-1", "uniprot_id": "OSBL7_HUMAN", "id": "Q9BZF2-1", "name": "Oxysterol-binding protein-related protein 7", "aln": "MDFQER-DPPFLPESAQSS----KPSSAQQAS-----------ELWEVVEEPRV--RLGTEGVMPERQ----EGHLLKKRKWPLKGWHKRYFVLEDGILHYATTRQDIT-------KGKLHGSIDVRLSVMSIN---KKAQRIDLDTEDNIYH--LKIKSQDLFQSWVAQLRAHRLAHRLDMPRGSL------------------PSTAHRKVPGAQLPTAATAS--ALPGLGPRE--KVSSWLRDSDGLDRCSHELSECQGKLQELHR--LLQSLESLHRIPSAP----VIPTHQASVTTERPKKGKRTSRMWCTQSFAKDDTIGRVGR----------------LHGSVPNLSRYLESRDSSGTRG----------------LPPTDYAHLQRSFWALAQKVHSS----LSSVLAALTMERDQLRDMHQGSELSR-------------------MGVSEASTGQRRLHSLSTSSDTTADSFSSLNPEEQEALYMKGRELTPQLSQT--SILSLADSHTEFFDACEVLLS-----------------------------------ASSSENEGSEEEESCTSEITTSLSEEMLDLRGAER-------------------CQKGGCVPGRPMGPPRRRCLPAASGPGADVSLWNILRNNIGKDLSKVSMPVQLNEPLNTLQRLCEELEYSSLLDQASRIADPCERMVYIAAFAVSAYSSTYHRAGCKPFNPVLGETYECERPDRGFRFISEQVSHHPPISACHAESENFAFWQDMKWKNKFWGKSLEIVPVGTVNVSLPRFGDHFEWNKVTSCIHNVLSGQRWIEHYGEVLIRNTQDSSCHCKITFCKAKYWSSN--VHEVQGAVLSRSGRVLHRLFGKWHEGLYRGPTPGGQCIWKPNSMPPDHERNFGFTQFALELNELTAELKRSLPSTDTRLRPDQRYLEEGNIQAAEAQKRRIEQLQRDRRKVMEENNIVHQARFFRRQTDSSGKEWWVTNNTYWRLRAEPGYGNMDGAVLW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AY80-1", "uniprot_id": "A0A8M3AY80_DANRE", "id": "A0A8M3AY80-1", "name": "Oxysterol-binding protein", "aln": "MDSVDH-NQSHMSGVEKVSSGWQKPSHSRSSSTASSRHSRLNVKDWEVMDDCPADLTITAENIQDANTPGICEGYLMKRRKWPLKGWHKRYFVLDKGILRYTKNQHDFS-------RGKMHGSLDVSLAVMSVN---KKARRIDLDAGDNLYH--LKAKSQDLYFIWVTKLSAHRMYKKNEAAHVHNGY---------LQVLSHTSNLSHKTSPMQDMGTSGSSMGENLQYVSPAVNGKVSAWLQTQE-PDFCGQELTRCQMELNELQR--LVQKLNSLESGQTVYNGDLQRMISMQNLSLDKPKK-KSAKIFGHSRTLSRVEGLGMPFRGITKSLSSSQLNSSSLLGTSVPSIPDYVSTPANSPAS------------------TSPESKKLHQDICSMSLKVHAS----LRTAHEALAQERQRLRDTWSGRDLHQN--------TSAQLNNLCSLAELDVNSRHTKIHKLSISSNSSDDSFRTVE---------QRKSVSSRCSSF--RAPSIADSVAEYFDACDELKC-----------------------------------ASSSEMSDESGLSDGSSNSEPYEAHAMASRKYRAS-------------------LSKAAAKPNTIKSTGRRTTLPAVCPDNSHVGLMTILYNNIGKDLSRVSMPAALNEPVCLLQRLCEELEYSDLLDTANHTDDPFQRMVYIAAFAISGYATAQFRNRYKPFNPVLGETFECIREDRGFRYISEQVSHHPPISACHADSDNFSFWQDQRWKNKFWGKSLEIMPTGMVNVTLKKYGDHYEWNKVVTCIHNVLSQQRYLEHYGEVIIQNLNSSVCTCKITFVKSRYWGADAARNQVQGQVLDQTGNVIHRFGGFWHEGIFCETLPVPQCIWKPNPQPKNYLLYYGFSSFAMEMNELVPELKPLLPPTDTRLRPDQRLLEEGKVEETDKKKDEVEEKQRERRKIMAKRGEEHIPRFFRKSLDAAGREVWLTNGTYWKIRENPGFANVNNLELW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P38713-1", "uniprot_id": "OSH3_YEAST", "id": "P38713-1", "name": "Oxysterol-binding protein homolog 3", "aln": "METIDIQNRSFVVRWVKCGRG--DVINYQIKPLKKSIEVGIYKKLKSSVDDHASAVHIAPDTKTLLDYT--TKSLLHKGSSSNIEEHHRRSSQHSHSSSNGSDNKRKERSYSSLSISGIQQQSQEIPLREKLSASGFTLVKRVGNVSGNTMVQGDLEVKDTDYYYAFILDNSSSKNAKKKILFNASVINGDNQSMISTRSTPPARPTALSRTSTQQDMLFRVGQGRYLQGYLLKKRRKRLQGFKKRFFTLDFRYGTLSYYLNDHNQTCRGEIVISLSSVSANKKDK---IIIIDSGMEVWVLKATTKENWQSWVDALQTCFDDQFEDKDTSTLEENPDILDDDKEVINKSSPQDHDHLTPTATTKSALSHRQHTQKDMDDIYVPLPSESYATFSMNLRLIQQRLEQCKKDSLSYKPTTLHQRSEGLNGTHSSSSVFTNNRVSSFNHSSSGMTSSDSLASEEVPSNKTYIEHALYNQLADLEVFVSRFVTQGEVLFKDHQILCKKAKDTRVSLTSYLSENDEFFDAEEEISRGVIILPDTEDDINNIVEETPLLGKSDQNEFTKEVQLSGSEQIASSSVESYTTNDENHSRKHLKNRHKNRRRGHPHHQKTKSAQSSTETFTSKDLFALSYPKSVTRRNDIPEAAAS--PPSLLSFLRKNVGKDLSSIAMPVTSNEPISILQLISETFEYAPLLTKATQRPDPITFVSAFAISFLSIYR-DKTRTLRKPFNPLLAETFELIREDMGFRLISEKVSHRPPVFAFFAEHLDWECSYTVTPSQKFWGKSIELNNEGILRLKFKTTGELFEWTQPTTILKNLIAGERYMEPVNEFEVHSSKGD--KSHILFDKAGMFSGRSEGFKVSIIPPPSSNRKKETLAGKWTQSLANETT--HETIWEVGDLVSNPKKKYGFTKFTANLNEITEIEKGNLPPTDSRLRPDIRAYEEGNVDKAEEWKLKLEQLQRERR----NKGQDVEPKYFEKVSKNE-WKYITGPKSYWERRKKHDWSDIS--QLW", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: : : . : : . . : . : . ::: : .: :. * * . :: *:* ... . : .::. * : * :: * . .:*:. : :.: : *: *. * : :: . : : :: . :. . : : ::..: : * *: . :: * :: .*.*: . .: :... : . : . : : : * *. :: . .: . .. . : .: : ::. . * :* . : *.. .. .: : :. : :. .. : : * : . : : : .. * .. *:*** : : *.** .. .. ::: . : . : * . . ** :* .. .* .:* :*:***** ::**. ***: ** :.* :**: ** *.: ** : :* :* * * *****:*.**:* * * *** ***:***:**: * .*: :: .:******:*: * :.:.: *: :**.: .: ::*::: :*::* .*. ::. :.. .:* * *: :.. :*. :.. . : * * :.: . : **: . : :**:.*: ::**:. * **.**:***** * ***::: :: * .:*: **:** :.. .::*.: . : :**. * : .:.::. **", "identical_positions": 140, "similar_positions": 275, "identity": "13.77%" }, { "cls_id": "homologset.agr.RGD:1309142", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZGB1-1", "uniprot_id": "NFAT5_RAT", "id": "D3ZGB1-1", "name": "Nuclear factor of activated T-cells 5", "aln": "-------------------------------------------------------------------------MPSDFISLLSADLDLESPKSLYSRDSLK--------------LHPSQNFHRAGLLEESVYDLLPKELQLPPPRETSAASMSQTSGGEAGSPPPAVVAADASSAPSSS-MGGACSSFTTSSSPTIYSTSVTDSKAMQVES---------CSSAVGVSNRGVSEKQLTGNTVQQHPSTPKRHTVLYISPPPEDLLDNSRMSCQDEGCGLESEQSCS-------------MWMEDSPSNFSNMSTSS---------------------------------------YN------------DNTEVPRKSRKRNPKQRPGVKRRDCEESNMDIFDADSAKAPHYVLSQLTTDNKGNSKAGNGTLDSQKGTGVKKSPMLCGQYPVKSEGK--------------------------------------------ELKIVVQPETQHRARYLTEGSRGSVKDRTQQGFPTVKLEGHNEPVVLQVFVGNDSGRVKPHGFYQACRVTGRNTTPCKEVDIEGTTVIEVGLDPSSNMTL----AVDCVGILKLRNADVEARIGIAGS---KKKSTRARLVFRVNITRKDGSTLTLQTPSSPILCTQPAGVPEILKKSLHSCSVKGEEEVFLIGKNFLKGTKVIFQENVS--------------------DENSWKSEAEIDMELFHQNHLIVKVPPYHDQHITLPVSVGIYVVTNAGRSHDVQPFTYTPDPAAG-ALSVNVKKEISSPARPCSFEEALKAMKTTGCNVDKVTILPNALITPLISSSMIKTEDVTPMEVTSEKRSSPIFQTTKTVGSTQQTLETISNIAGN-ASFSSPSSS-HLSPENENQQQLQPKAYNPETLTTIQTQDISQPGTFPAVSASSQLPSSDALLQQAAQFQTRDAQSRDTMQSD-SVVNLSQLTEAPQQQQ-SPLQEQAQ-----IPSNIFPSPNSVSQLQSTIQQLQAGSFTGSTASGSNGSVDLVQQVLEAQQQLSSVLFSTPDGNENVQEQLNADIFQ-VSQIQNSVSPGMFSSTESAVHTRPDNLLPGRADSVHQQTENTLSSQQQQQQQQQQQQQQQVIESSAAMVMEMQQSICQAAAQIQSELFPSAASANGSLQQSPVYQQPSHMMSALPTSEDMQMQCELFSSPPAVSGNETSTTTTPQVATPGSTMFQPPNSGDGEETGAQAKQIQSSVFQTMVQMQHSGDSQPQVNLFSSTKNIMSVQSNGTQQQGNSLFQQGSEMLSLQSGSFLQQSSHSQAQLFHPQNPIADAQSLSQETQGPMFHSANPIVHSQTSTASSEQLQPSMFHSQSTIAVLQGSSVPQDQQ--SPNIYLSQSSISNLQTNTVAQEEQISFFSAQNSISPLQSTSNTEQQAAFQQQPPISHIQTPLLSQEQAQPSQQGLFQPQVALGSLPANPMPQNQQGPIFQTQRPIVGMQSNSPSQEQQQQQQQQQQQQQQQQQQ--SILFSNQNAMATMASQKQPPPNMIFSPNQNPMASQEQQNQSIFHQQSNMAPMNQE--QQPMQFQNQPTVSSLQNPGPTPSESPQTSLFHSSPQIQLVQGSPSSQEQQVTLFLSPASMSALQTSINQPDMQQSPLYSPQNNIPGIQGSTSSPQPQ-AALFHNTTGGTINQLQNSPGSSQQTSGMFLFGIQNNCSQLLTSGPATLPEQLMAINQPGQPQNEGQSSVTTLLSQQMPESAPLASSVNNSQNMEKIDLLVSLQS----QGNNLTGSF--------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WV30-1", "uniprot_id": "NFAT5_MOUSE", "id": "Q9WV30-1", "name": "Nuclear factor of activated T-cells 5", "aln": "-------------------------------------------------------------------------MPSDFISLLSADLDLESPKSLYSR--------------------------------ESVYDLLPKELQLPPPRETSVASMSQTSGGEAGSPPPAVVAADASSAPSSSSMGGACSSFTTSSSPTIYSTSVTDSKAMQVES---------CSSAVGVSNRGVSEKQLTGNTVQQHPSTPKRHTVLYISPPPEDLLDNSRMSCQDEGCGLESEQSCS-------------MWMEDSPSNFSNMSTSS---------------------------------------YN------------DNTEVPRKSRKRNPKQRPGVKRRDCEESNMDIFDADSAKAPHYVLSQLTTDNKGNSKAGNGTLDSQKGTGVKKSPMLCGQYPVKSEGK--------------------------------------------ELKIVVQPETQHRARYLTEGSRGSVKDRTQQGFPTVKLEGHNEPVVLQVFVGNDSGRVKPHGFYQACRVTGRNTTPCKEVDIEGTTVIEVGLDPSNNMTL----AVDCVGILKLRNADVEARIGIAGS---KKKSTRARLVFRVNITRKDGSTLTLQTPSSPILCTQPAGVPEILKKSLHSCSVKGEEEVFLIGKNFLKGTKVIFQENVS--------------------DENSWKSEAEIDMELFHQNHLIVKVPPYHDQHITLPVSVGIYVVTNAGRSHDVQPFTYTPDPAAG-ALNVNVKKEISSPARPCSFEEAMKAMKTTGCNVDKVTILPNALITPLISSSMIKTEDVTPMEVTSEKRSSPIFQTTKSIGSTQQTLETISNIAGG-APFSSPSSSSHLTPESENQQQLQPKAYNPETLTTIQTQDISQPGTFPAVSAASQLPSSDALLQQATQFQTREAQSRDTIQSD-TVVNLSQLTEASQQQQ-SPLQEQAQTLQQQIPSNIFPSPSSVSQLQSTIQQLQAGSFTGSAAGGRSGSVDLVQQVLEAQQQLSSVLFSTPDGNENVQEQLNADIFQ-VSQIQNSVSPGMFSSAESAVHTRPDNLLPGRADSVHQQTENTLSNQQQQQQQQQQ-----VMESSAAMVMEMQQSICQAAAQIQSELFPSAASASGSLQQSPVYQQPSHMMSALPTNEDMQMQCELFSSPPAASGNETSTTTTPQVATPGSTMFQTPSSGDGEETGAQAKQIQNSVFQTMVQMQRSGDSQPQVNLFSSTKNIMSVQNNGTQQQGNSLFQQGSEMMSLQSGNFLQQSSHSQAQLFHPQNPIADAQNLSQETQGSIFHSPNPIVHSQTSTASSEQLQPSMFHSQNTIAVLQGSSVPQDQQ--SPNIFLSQSSINNLQTNTVAQEEQISFFAAQNSISPLQSTSNTEQQAAFQQQPPISHIQTPILSQEQAQPSQQGLFQPQVALGSLPPNPMPQNQQGPIFQTQRPIVGMQSNSPSQEQQQQQQQQQQQQQQQQQQQQSILFSNQNAMATMASQKQPPPNMMFSPNQNPMASQEQQNQSIFHQQSNMAPMNQE--QQPMQFQNQPTVSSLQNPGPTQSESPQTSLFHSSPQIQLVQGSPSSQDQQVTLFLSPASMSALQTSINQPDMQQSPLYSPQNNIPGIQGSTSSPQPQ-ATLFHNTTGGTINQIQNSPGSSQQTSGMFLFGIQNNCSQLLTSGPATLPDQLMAINQQGQPQNEGQSSVTTLLSQQMPETSPLASSVNSSQNMEKIDLLVSLQS----QGNNLTGSF--------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O94916-1", "uniprot_id": "NFAT5_HUMAN", "id": "O94916-1", "name": "Nuclear factor of activated T-cells 5", "aln": "-------------------------------------------------------------------------MPSDFISLLSADLDLESPKSLYSR--------------------------------ESVYDLLPKELQLPPSRETSVASMSQTSGGEAGSPPPAVVAADASSAPSSSSMGGACSSFTTSSSPTIYSTSVTDSKAMQVES---------CSSAVGVSNRGVSEKQLTSNTVQQHPSTPKRHTVLYISPPPEDLLDNSRMSCQDEGCGLESEQSCS-------------MWMEDSPSNFSNMSTSS---------------------------------------YN------------DNTEVPRKSRKRNPKQRPGVKRRDCEESNMDIFDADSAKAPHYVLSQLTTDNKGNSKAGNGTLENQKGTGVKKSPMLCGQYPVKSEGK--------------------------------------------ELKIVVQPETQHRARYLTEGSRGSVKDRTQQGFPTVKLEGHNEPVVLQVFVGNDSGRVKPHGFYQACRVTGRNTTPCKEVDIEGTTVIEVGLDPSNNMTL----AVDCVGILKLRNADVEARIGIAGS---KKKSTRARLVFRVNIMRKDGSTLTLQTPSSPILCTQPAGVPEILKKSLHSCSVKGEEEVFLIGKNFLKGTKVIFQENVS--------------------DENSWKSEAEIDMELFHQNHLIVKVPPYHDQHITLPVSVGIYVVTNAGRSHDVQPFTYTPDPAAAGALNVNVKKEISSPARPCSFEEAMKAMKTTGCNLDKVNIIPNALMTPLIPSSMIKSEDVTPMEVTAEKRSSTIFKTTKSVGSTQQTLENISNIAGN-GSFSSPSSS-HLPSENEKQQQIQPKAYNPETLTTIQTQDISQPGTFPAVSASSQLPNSDALLQQATQFQTRETQSREILQSDGTVVNLSQLTEASQQQQQSPLQEQAQTLQQQISSNIFPSPNSVSQLQNTIQQLQAGSFTGSTASGSSGSVDLVQQVLEAQQQLSSVLFSAPDGNENVQEQLSADIFQQVSQIQSGVSPGMFSSTEPTVHTRPDNLLPGRAESVHPQSENTLSNQQQQQQQQQQ-----VMESSAAMVMEMQQSICQAAAQIQSELFPSTASANGNLQQSPVYQQTSHMMSALSTNEDMQMQCELFSSPPAVSGNETSTTTTQQVATPGTTMFQTSSSGDGEETGTQAKQIQNSVFQTMVQMQHSGDNQPQVNLFSSTKSMMSVQNSGTQQQGNGLFQQGNEMMSLQSGNFLQQSSHSQAQLFHPQNPIADAQNLSQETQGSLFHSPNPIVHSQTSTTSSEQMQPPMFHSQSTIAVLQGSSVPQDQQ--STNIFLSQSPMNNLQTNTVAQEA---FFAAPNSISPLQSTSNSEQQAAFQQQAPISHIQTPMLSQEQAQPPQQGLFQPQVALGSLPPNPMPQSQQGTMFQSQHSIVAMQSNSPSQEQQQQQQQQQQQQQQQQQS---ILFSNQNTMATMASPKQPPPNMIFNPNQNPMANQEQQNQSIFHQQSNMAPMNQE--QQPMQFQSQSTVSSLQNPGPTQSESSQTPLFHSSPQIQLVQGSPSSQEQQVTLFLSPASMSALQTSINQQDMQQSPLYSPQNNMPGIQGATSSPQPQ-ATLFHNTAGGTMNQLQNSPGSSQQTSGMFLFGIQNNCSQLLTSGPATLPDQLMAISQPGQPQNEGQPPVTTLLSQQMPENSPLASSINTNQNIEKIDLLVSLQN----QGNNLTGSF--------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TU54-1", "uniprot_id": "A0AB32TU54_DANRE", "id": "A0AB32TU54-1", "name": "Nuclear factor of activated T-cells 5", "aln": "-------------------------------------------------------------------------MPSDFTSLFSADIDLDSPKSLYSK--------------------------------ESVYDLLPKELQLPSSGVQSAAAMSQKSGGEAGPPPPAALAADASSASSAMSSGSPRSAFPTSASD--RSTVHDSGSSGDVSS---------RRKSEAVENKPSGRD----KGVQQTQMTPSKRPVLNISPPPEDLFDDSHMSCQDD-LLLDSEQSSS-------------IWIENSVSNFSIVSSSS---------------------------------------YN------------DNTEVPRKARKCTPRQKPGPKPVSAEEASMDVFDADSAKGPHFVLSQLGPDSKTCSKASS---DGPQVSALKGG-VLSCQYPQKGEGK--------------------------------------------ELKIVVQPETQHRARYLTEGSRGSVKDQTQQGFPTIKLEGVKESVVMQIFVGNDAGRVKPHGFYQACRVTGRNTTACREVDIEGTTVIEVPMDPSSNMTLPCLCSVDCVGILKLRNADVEARIGVAGS---KKKSTRARLVFRVNIPRPDGSALTLQTSSSPILCTQPAGAPEILKKSLHSCSVKGGNEVFIIGKNFLKGTKVIFQENASA-------------------DDKSWKAEADIDMEFFHQNHLIVKVPPYQNPAITSPISVGIYVVTNAGRSHDVQQFTYTPEPVVD----SSVKKEDLPPVTPCCFEQ--------------IKVIDTAVMTPGLP--LVKREEATPMEVSGN--PSDFKQTSEVINSAQQALDMSTEISTNNCKFSSPLAH----PTREPDQSQNSVFSNKEPFNTIQEQNLASSGSFHVPNKSLLQQGVQPFLLEHRDRLGQEMPG----SSGSSVVALSQLDDNPQQQL-----------------SLLP-PDEVAQLEQAVRQLQAKGYCG----------------------------------------------------------------------------------IQLQSENSLSKQRQHQLQQQQ-----------QQIQQQQHQIHQQQQQIQQQQQHIQHQE----QQIQLQQQHHHQQQALEN-----LQHQLFQPQVQIHCSSEQQSSSQGMVQNGSSLFQSTPS----------------------QQQ--------------------------QQQQATLFQQG-------AGFLQQQPSHSSPSMFHNTTAMTEAQ----SPQESLFHT-------QKTSPNQDQVQASIFQSN--LSVLSGSNMSSEAQPSAASMFLPQNTVPAQLSVNANQPQQLAFLTSMQTSLEAPSVFQTPTQLSPIQQG------TPMDQQQSPQHAQPGSMFQSISQSPSKLTPGQQQQAGLLLG--------SLNSPITQEQSSN----------------LLFGGQVQIGSMNN--------------SSLASSEQQNTPLPFAQAGLVTVRQQEASEPMTFQDQTAMVVN--------LSSNKPIFQDQQPMQLAPSSNPGSSQSVNLFMAQSNMQGGMT-------TQEALFAPQGDVGGIQTSTSSPVQQPGQLFQTTMSGSLNQP-----NQDQQTDLFLFEIQNECRQLMNSQGSTLSNQIITINQPGQSQQESDGQIQSLLGQAMPDPGAVQSTLTTSQNMEKIDDLLSYHQGDTPHSKKVAGSSPSWVSWHFCVELACSPRVRVGFLRVLRFSPQSKGMQYR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A8JUV3-1", "uniprot_id": "A8JUV3_DROME", "id": "A8JUV3-1", "name": "Nuclear factor of activated T-cells 5", "aln": "MRFTYNQYKHYESGYRIPSKMHNLSHNNNNNSNNNNNGGGHTNNNNNGNNSGHHYAHHNNSNNGGNNNTNFQAYQHHYKSNFGMRMTMSTNSTMSARIHRKGFRIPSKRQPGKGLPGKLHTITRTGPGKMVPGKRIPQRPHPPPCDNSNDSGLGFDQHTELRSSAGAGGVTDPAANGGSGSNSGQRSSLLVNSALTNTVAAAAAAAAAAVASNTLQQHQQHHQQQQQQQQQQQQQQQQQQQQQQQQQHSPQQHLIRAIPVSRSRNNTKVMAHCLEDLDLISASSEDSSTIATPAGLDEDTGFVNDTKTTTTGGNSSSDPFGGVFQATEAAVAAAVNAFNLQQQQHSVQQQQHQLFQYNGLLLQPQQQLQQQQSHHQQQQQQQQHHRHGKHIKRKKLECNQVELDNDDACSEDEFIRKIASSVTMSPTLEATPSPPPIVASVAPATTIVSLLPLISSGNSNNNNNNNNIETKFISARNVTRVANKRQPTTPLNSVASSNDGQVQLEILSQPEQQHRARYQTEGSRGAVKDRSGNGFPIVRLTGYDKVAVLQVFIGTDIGRVAPHMFYQACKVAGKNSTQCNEKKVDGTMVIEIDFKPETDMTI----TCDCVGILKERNVDVEHRFPEHLAQKNKKKSTRCRMVFRTQLTRDDGTTETLQVCSNPIICTQPPGVPEICKKSLNSCPVDGGLELFIIGKNFLKDTHVVFQETYDSVNGDDPATEIAVRQQLIGGTAALWEQSVLPDKEYLHQTHLICTVPPYLHQNILKPVQVQVSIVS-SGKKSEPHTFTYTAKGQYTTLAAASTLSNTIHAQDVSGFMD-----------------------TTSASNASGSSGWSAAGGSGNNTSTGDNVEAKHEIDSGMMPPPITTQIPMGVRRSSLPSVT----PMITDQQLVHLNAVAAS--AEALKTELDDSNSHSPLTGESTPDSPNAALQYHRFAR----------KPSLDTIMYDQSNSLPGFPT-------------------VVAPATAAAVAAAVDIDPTAVAVA----------------------------------------------------------------------------------VELAVKNEIVKHVVQQHQQMQ-----------EQMHEQQQQQQQQQQQQQQQQ-----------QQQPQQQQQ-------------QQVHKFIDELTKSTSVVSSNGTTEPALFTTSAVIDHALT----------------------------------------------------------------------DILQAKVGIAPPNVVLERSLSLSSTNSSSSMSG------------SESSPNSSPLTQDIILNSEPAAALAGAAALGGPAP----VDVTGGLSTDIIMNPAVSPSTILCSANGAATAVVPNILAPHQVTMANSILN--------DIAMQPEPTQQDAAVAALALSNIMMSP-PTAASGVGVG--------DTLPPTPATMQP-------------------------------------------EVAATATSTAVSNMIIKAAADFITTQEQ---EQHHYHHHGRIHSHSPQAAVGVSGNPAETASDPLVDLLLNHSNTPETAAAAAAAVAVEAANFQS-------MNHSHHSHHGHHGHSHGHGHSRVTG---HVSGHVTSHHRGHHLPVVPPTPQESLIVALASENALQKSVATAAVTTNGAVMTQQASAPNTAGSILPAAVGAVAAAAAVAVQPPIPQELTTMSDQDLISYIN-----PSTFDQL---------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: * :. : :.: .:: :: . :*:. : *. . :.:. . * ... * .:*.:: .: .. *:: ..:: : . : * * . .:: .. : ** :*.:: : *. . . . * :: :.:... * ::::: :. : .:** ** :::. :: :: ::: . *.. :* *.* . . .: :: .. . .. :.: . : * ..*: :*:*: *** ****** ******:***:: :*** ::* * .: .*:*:*:*.* *** ** *****:*:*:*:* *.* .::** ***: :.*..:**: : ******* **.*** *: : ******.*:***.:: * **:: ***. *.**:****.*.*** ****:**.*.* *:*:*******.*:*:***. . *: .. * * :**.*** .**** . * *:.* : :*: :*:. : : ****.. .. .: . . * : *. . . :. : .. ::.. :.* . ::*. . * * . :* : . :: ...:. . . :. * ... .: .* . . . * .: : :: : . :. :* : .: :* ** * : : *:. * * *.: ** ** :::. . :: ::::: . : . : : . : ..:. . .: . . . ::.... : :: .. :.* *: : :. . . . : : . . . ..: .* . :: . .* * . . .* . . *.. . : :.: . .:: : :: : : . . * * . . . . : : . .: :.. : * . . . .::: .::. * : :. .: : .* . .: .. :: . . .: ..: . . . : *:* . ... ", "identical_positions": 199, "similar_positions": 401, "identity": "10.82%" }, { "cls_id": "homologset.agr.RGD:1309143", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZUK3-1", "uniprot_id": "DLK2_RAT", "id": "D3ZUK3-1", "name": "Protein delta homolog 2", "aln": "-------MPSGCRCLN-LVCLLCILGATSQPARADDCS-SHCDLAHGCCAPDGSCRCDPGWEGLHCERCVRMPGCQHGTCHQPWQCICHSGWAGKFCDKDEHICTSQSPCQNGGQCVYDGGGEYHCVCLPGFRGRGCERKAGPCEQAGFPCQNGGQCQDNQGFALNFTCRCLAGFMGAHCEVNVDDCLMRPCANGATCIDGINRFSCLCPEGFAGRFCTINLDDCASRPCQRGARCRDRVHDFDCLCPSGYGGKTCELVLPAPDP-ATIGTPQAPASAVVVPATGSAPHSAGAGLLRISVKEVVRRQEAGLGESSLVALVVFGSLTAALVLATVLLTLRAWRRGICPTGPCCDPAPHYAPARQDQECQVSMLPAGFPLSPDLPPEPGKTTAL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K1E3-1", "uniprot_id": "DLK2_MOUSE", "id": "Q8K1E3-1", "name": "Protein delta homolog 2", "aln": "-------MPSGCRCLN-LVCLLCILGATSQPARADDCS-SHCDLAHGCCAPDGSCRCDPGWEGLHCERCVRMPGCQHGTCHQPWQCICHSGWAGKFCDKDEHICTSQSPCQNGGQCVYDGGGEYHCVCLPGFHGRGCERKAGPCEQAGFPCRNGGQCQDNQGFALNFTCRCLAGFMGAHCEVNVDDCLMRPCANGATCIDGINRFSCLCPEGFAGRFCTINLDDCASRPCQRGARCRDRVHDFDCLCPSGYGGKTCELVLPAPEP-ASVGTPQMPTSAVVVPATGPAPHSAGAGLLRISVKEVVRRQESGLGESSLVALVVFGSLTAALVLATVLLTLRAWRRGICPTGPCCYPAPHYAPARQDQECQVSMLPAGFPLSPDLPPEPGKTTAL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6UY11-1", "uniprot_id": "DLK2_HUMAN", "id": "Q6UY11-1", "name": "Protein delta homolog 2", "aln": "-------MPSGCRCLH-LVCLLCILGAPGQPVRADDCS-SHCDLAHGCCAPDGSCRCDPGWEGLHCERCVRMPGCQHGTCHQPWQCICHSGWAGKFCDKDEHICTTQSPCQNGGQCMYDGGGEYHCVCLPGFHGRDCERKAGPCEQAGSPCRNGGQCQDDQGFALNFTCRCLVGFVGARCEVNVDDCLMRPCANGATCLDGINRFSCLCPEGFAGRFCTINLDDCASRPCQRGARCRDRVHDFDCLCPSGYGGKTCELVLPVPDPPTTVDTPLGPTSAVVVPATGPAPHSAGAGLLRISVKEVVRRQEAGLGEPSLVALVVFGALTAALVLATVLLTLRAWRRGVCPPGPCCYPAPHYAPACQDQECQVSMLPAGLPLPRDLPPEPGKTTAL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PYA6-1", "uniprot_id": "A0A8M9PYA6_DANRE", "id": "A0A8M9PYA6-1", "name": "Protein delta homolog 2", "aln": "MKLAVVLLLCGCCVLFKHNCEAQVLFSSEETSPTPSASNCTCEIGHGKCAENGDCRCDPGWGGPMCDDCVRMPGCVHGTCHQPWQCSCMDGWAGRFCDKDVYVCSRQQPCHNGATCELSDSGDYSCLCPEGFHGRDCELKAGPCQKTKSPCKNGGLCEDLGGYAPELSCRCLAGFTGARCETNMDDCLMRPCANGATCLDGVNRFSCLCPAGFTGRFCTINLDDCASQPCLNGGRCIDRVSNFQCVCPLGFTGRTCELVSPTKSP---LKAEHNPN-MTLKPSHWTTPSGGEERLLKITFRTPAGGE--GLSEFQLIVLLVLGGMTLAVVGLTAALVLRGYFQDRSASCQCR-PAHRTQRKHSQQECKISFLQS--PEKKRLN-----TDVI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .** * * :* :. :. : ..* . *::.** ** :*.******* * *: ******* ********** * .****:***** ::*: *.**:**. * ...*:* *:* **:**.** *****::: **:*** *:* *:* :::****.** **:**.*:**************:**:******** **:*************:** .*.** *** :*:*:** *: *:***** *. .* : : * .: *: .:* .. **:*:.: . : **.* .*:.*:*:*.:* *:* *. *.**.: :. ... * ** : .:***::*:* : * * * .:", "identical_positions": 181, "similar_positions": 100, "identity": "46.17%" }, { "cls_id": "homologset.agr.RGD:1309144", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q80W22-1", "uniprot_id": "THNS2_MOUSE", "id": "Q80W22-1", "name": "Threonine synthase-like 2", "aln": "-----MWYTSTRGMAP-RVNFEGALFSGYAPDGGLYMPEELPRLDEETLR-HWSTLSYRSLVKELCALFIGLELIPRHDLNDLIDRAFSRFRHRNVVHLCKLKNG----LNILELWHGVTYAFKDLSLSCTAQFLQYFLEKK--------KKHVTIVVGTSGDTGSAAIESVQGSKNVDIIVLLPKGHCSKIQELQMTTVLKENVHVFEVEGNSDELDEPIKAVFADVAFVQRHNVMSLNSINWSRVLVQMAHHFFAYFQCTPSL-DTHPLPTVEVVVPTGAGGNLAAGCIAQKMGLPIC-LVVAVNRNDIIHRTVQKGDFSLCEVLRTTLASAMDIQVPYNMERIFWLLS---------GSDSQTTRALMEQFERTQSLQLPKDLHNKLSEAVTSESVTDEAITQTMARCWEE----NQYLLCPHSATAVNYHYQQTDSGQSS--IRCCLASASAVKFPEAVQAAG--------LTPETPAEILALEHKETRCIPMRRGDDWTQMLRVTIEGLSQRWKDCVVNPSE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5M7T9-1", "uniprot_id": "THNS2_RAT", "id": "Q5M7T9-1", "name": "Threonine synthase-like 2", "aln": "-----MWYTSTRGMAP-RVNFEGALFSGYAPDGGLYMPEELPRLDKETLR-HWSTLSYRSLVKELCALFVGLELIPRHDLNGLIDQAFSRFRHRDVVHLCKLKNG----LNILELWHGVTYAFKDLSLSCTAQFLQYFLEKK--------KKHVTIVVGTSGDTGSAAIESVQGSKNVDIIVLLPKGHCSKIQELQMTTVVKENVHVFGVEGNSDELDEPIKAVFADVAFVQRHNLMSLNSINWSRVLVQMAHHFFAYFQCTPSL-DMHLLPTVEVVVPTGAGGNLAAGCIAQKMGLPIS-LVVAVNRNDIIHRTVQKGDFSLCEVVRKTLASAMDIQVPYNMERIFWLLA---------GSDSQTTRALMEQFERTQSLHLPKDLHSKLSEAVTSESVSDEAITQTMGRCWEE----NQYLLCPHSATAVSYHYQQTDSGQPSSIPRCCLAPASAVKFPEAVQAAG--------LTPETPAEILALEHKETRCTPMRRGDDWTQMLRDTIEALSLRWKGCVENTAE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q86YJ6-1", "uniprot_id": "THNS2_HUMAN", "id": "Q86YJ6-1", "name": "Threonine synthase-like 2", "aln": "-----MWYVSTRGVAP-RVNFEGALFSGYAPDGGLFMPEELPQLDRGTLC-QWSTLSYPGLVKELCALFIGSELLPKDELNDLIDRAFSRFRHREVVHLSRLRNG----LNVLELWHGVTYAFKDLSLSCTTQFLQYFLEKR--------EKHVTVVVGTSGDTGSAAIESVQGAKNMDIIVLLPKGHCTKIQELQMTTVLKQNVHVFGVEGNSDELDEPIKTVFADVAFVKKHNLMSLNSINWSRVLVQMAHHFFAYFQCTPSL-DTHPLPLVEVVVPTGAAGNLAAGYIAQKIGLPIR-LVVAVNRNDIIHRTVQQGDFSLSEAVKSTLASAMDIQVPYNMERVFWLLS---------GSDSQVTRALMEQFERTQSVNLPKELHSKLSEAVTSVSVSDEAITQTMGRCWDE----NQYLLCPHSAVAVNYHYQQIDRQQPS-TPRCCLAPASAAKFPEAVLAAG--------LTPETPAEIVALEHKETRCTLMRRGDNWMLMLRDTIEDLSRQWRSHALNTSQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q2YDP8-1", "uniprot_id": "THNS2_DANRE", "id": "Q2YDP8-1", "name": "Threonine synthase-like 2", "aln": "-----MRYCSTRAGVQ-GRSFRDVLFSGYAADGGMFMPENLPSLSAETLR-SWRRLSYRQLLCEVCELFIPEQEIPREQLEGLVSSALSSFSVPDAVRLVQLKDS----LSILELFHGETLAFKDLAMSCTAHFLQYFLRRD--------RQRATILVGTSGDTGSSAIRSVLGLREVDIVVVFPRGRITKIQELQMTTSVAENVHVFAADGTSDDIDVPLRKLFADADLVQRHRLMSLNSVNWSRIMVQTAHFLFAYLQLTPSLPEGDTLPVLEVLVPTGGAGNITAGIIVKRMGVPLR-LVAMVNANDIVHRTVQSGDFSMSSSVTQTLAPAIDIQDPYNMERVFWLLS---------GGDGLMVKSLMEEFQKTHKLSLPASLHQQLSEVLSSGSVSDDGILEAMRRCWQD----NHYLICPHTAVAVWRHYQSPVRPGES---RCCIATASPHKFQQAVQRAG--------LTLELPESLQVLDQLETRCADLKCSDDWEETLRRHIESISSRRNS-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P16120-1", "uniprot_id": "THRC_YEAST", "id": "P16120-1", "name": "Threonine synthase", "aln": "MPNASQVYRSTRSSSPKTISFEEAIIQGLATDGGLFIPPTIPQVDQATLFNDWSKLSFQDLAFAIMRLYIAQEEIPDADLKDLIKRSYSTFRSDEVTPLVQNVTGDKENLHILELFHGPTYAFKDVALQFVGNLFEYFLQRTNANLPEGEKKQITVVGATSGDTGSAAIYGLRGKKDVSVFILYPTGRISPIQEEQMTTVPDENVQTLSVTGTFDNCQDIVKAIFGDKEFNSKHNVGAVNSINWARILAQMTYYFYSFFQATNGK----DSKKVKFVVPSGNFGDILAGYFAKKMGLPIEKLAIATNENDILDRFLKSGLYERSDKVAATLSPAMDILISSNFERLLWYLAREYLANGDDLKAGEIVNNWFQELKTNGKFQVDKSIIEGASKDFTSERVSNEETSETIKKIYESSVNPKHYILDPHTAVGVCATERLIAKDNDKSIQYISLSTAHPAKFADAVNNALSGFSNYSFEKDVLPEELKKLSTLKKKLKFIERAD--VELVKNAIEEELAKMKL-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ***. .*. .::.* *.***:::* :* :. ** * **: * : *:: : :* :*:.*:. : * * :.. * : . * :***:** * ****:::. . ::::***.: .:: *:: .*******:** .: * :::.:.:: * *: : *** **** :**:.: . *. *: : :: :*.* : .:*.: ::**:**:*::.* ::.:::::* * . ::.:**:* *:: ** :.:::*:*: *. .* ***:.* ::.* :. .. : **:.*:** . *:**::* *: . .. ::::: . .. : .: . *: .:* *::: ::: : ::. ::*:: **:*..* : . .::.* . ** :** * . * .: *. :.: :. .* :: ** : . ", "identical_positions": 118, "similar_positions": 187, "identity": "22.39%" }, { "cls_id": "homologset.agr.RGD:1309145", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A6T9-1", "uniprot_id": "A0A8I6A6T9_RAT", "id": "A0A8I6A6T9-1", "name": "Transcription termination factor 2", "aln": "MEVIKCPEHGKVPVSGFPSWGLWNWLAGAIADLLVSSGAVCFLKTGVRDGPNKGKSFYVCRTNTCGFVQATDIPVSHCLLHEEFVVELQGLFLPQGKKEWRLFFRCARTKAEGKRWCGDVPWQ-DPNPKGHSVTCKPQLASESLPHPPSQPRNPFRVLNKNQKTLEWKQFVEGEGEIKTADKKLRENREQLLDQKKEQKPKSKCRMEKDPSSDLVVTR-QSGGDGEEQEEKTKFRPKTKET-------EEMTSKQGHG-EVLQGTSKVPQISESESQEIPNKPEALSEKETHLLLQSIPGQNPESKVQKEGHLIRE--QLKNGDKTGADAHSAQASQTGLSQGSLQ-GPSKTWRPTP------KARVAPGVCSGSVHHATSSSDDSEDDG------RPGSPLLFDLTIDSQKKGSLQHSDQSVQRQTAAASGVSKKGESSDLAAQRANLTTQLKQKKGTLAAVNIQALPDKGEKLLKQIQALEDALNALALSPEQGTRENCSSQEPEQSKVTETAAAGPLHLVPPQPLPRPHIQPAASLGLKASRQETPEGASQCSGGHTNEHRLYNVWKITSEAIDELHRSLESCPGKTAVAEDP--AGLKVPLLLHQKQALAWLLWRESQKPQGGILADDMGLGKTLTMIALILTKKNQQKSKEKDRSLPVMWLSKNDSSVFTSTG--------------TLIVCPASLIHHWKNEIEKRVNSNKLRIYLYHGPNR-IQHAKVLSTYDIVITTYSLLAKEIPTAKHEGEVPGAKLSVEGISAPLLQVVWARIILDEAHNVKNPRVQTSIAVCKLQAQARWAVTGTPIQNNLLDMYSLMKFLRCSPFDEFSLWKSQVDNGSMKGGERLSILTKSLLLRRTKDQLDSTGKPLVPLPARSCQLHRLKLSEDERAVYDVFLARSRSALQSYLKRQEGRGSHPGRSPENPFSRVAQEFGSGV---------PQCSTAADSRRPSTVHVLSQLLRLRQCCCHLSLLKSVLD-------------PKELESEGLVLSLEEQLSALTLSKVDV--SEPSPTVSLNG------------------------------------------TCFKVELFDDIRRSTKVSSLLAELEAIQKGPGSQKSVIVSQWTSMLQVVALHLRKNRLTYATIDGSVNPKQRMDLVEAFN-HSQGPQVMLISLLAGGVGLNLTGGNHLFLLDMHWNPSLEDQACDRIYRVGQEKDVVMHRFVCEGTVEEKILQLQEKKKDLAKQVLSG-----SGGPVTKLTLADLKILFGI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5NC05-1", "uniprot_id": "TTF2_MOUSE", "id": "Q5NC05-1", "name": "Transcription termination factor 2", "aln": "MDLVKCPEHG----------------------------DACFLKTGVRDGPNKGKSFYVCRTNTCGFVQATDIPVSHCLLHEEFVVELQGLFLPQDKKEWRLFFRCARTKAEGKQWCGNVPWRQDPNPKELSVTSKPQQPSESQLHSPSQPRNPFRVLNKNQKTLERKQFVE-EGERKTADKKLRENNEQLLDQRKEQKPKSNSRMEKDPSSDLVATR-QSGGDREEQE-KSKFQPKTKKA-------EGMASKQGHG-EVLQGIPKGPHMSESESRGVPNKPETLREKETQLLVPSVPGQNPESKVQKEGHVSRE--PLKNGE-----APSAQVTQRGLAQGPLQ-GPSKTWRPVP------EAPAAPELCSGMAHHATSSSEDSEDDGV---SSRPGSPLLFDSTVDSQKKGSLQHSDQSVQRQMPAASGVSKKGDSSDPAAQRANLTTQLKQKKGTLAAVNIQALPDKGEKLLKQIQALEDALSALALSPEQGTKEKCSAQEPEQSNITKAAAA-PLHLVPPQPLPRPLIQPASSLGLKAGRQETPEGASQCSGGHMNQHHLYNVWKITSEAIDELHRSLKSCPGETAVAEDP--AGLKVPLLLHQKQALAWLLWRESQKPQGGILADDMGLGKTLTMIALILTKKNQQKSKEKERSEPVTWLSKNDSSVFTSSG--------------TLIVCPASLIHHWKNEVEKRVTSNRLRIYLYHGPNR-SRHAKVLSTYDIVITTYSLLAKEIPTTKQEGEVPGANLSVEGTSAPLLQVVWARIILDEAHNVKNPRVQTSIAVCKLQAQARWAVTGTPIQNNLLDMYSLMKFLRCSPFDEFSLWKSQVDNGSMKGGERLSILTKSLLLRRTKDQLDSTGKPLVALPARRCQLHRLKLSEDERAVYDIFLARSRSALQSYLKRQEGRGSHHGRSPDNPFSRVAQEFGSSV---------SQGCPAADSQRPSTVHVLSQLLRLRQCCCHLSLLKSALD-------------PTELESEGLVLSLEEQLSALTLSKVDV--SEPSPTVSLNG------------------------------------------TCFKAELFDDTRRSTKVSSLLAELEAIQKGPGSQKSVIVSQWTSMLQVVALHLKKNRLTYATIDGSVNPKQRMDLVEAFN-HSQGPQVMLISLLAGGVGLNLTGGNHLFLLDMHWNPSLEDQACDRIYRVGQKKDVVIHRFVCEGTVEEKILQLQEKKKDLAKQVLSG-----SEGPVTKLTLADLKILFGI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UNY4-1", "uniprot_id": "TTF2_HUMAN", "id": "Q9UNY4-1", "name": "Transcription termination factor 2", "aln": "MEEVRCPEHG----------------------------TFCFLKTGVRDGPNKGKSFYVCRADTCSFVRATDIPVSHCLLHEDFVVELQGLLLPQDKKEYRLFFRCIRSKAEGKRWCGSIPWQ-DPDSKEHSVSNKSQHASETFHHSSNWLRNPFKVLDKNQEPALWKQLIKGEGEEKKADKKQREKGDQLFDQKKEQKPE---MMEKDLSSGLVPKKKQSVVQEKKQEEGAEIQCEAETGGTHKRDFSEIKSQQCQGNELTRPSASSQEKSSGKSQDVQRESEPLREKVTQLLPQNVHSHNSISKPQKGGPLNKEYTNWEAKETKAKDGPSIQATQKSLPQGHFQERPETHSVPAPGGPAAQAAPAAPGLSLGEGREAATSSDDEEEDDVVFVSSKPGSPLLFDSTLDLETKENLQFPDRSVQRKVSPASGVSKKVEPSDPVARRVYLTTQLKQKKSTLASVNIQALPDKGQKLIKQIQELEEVLSGLTLSPEQGTNEKSNSQVPQQSHFTKTTTG-PPHLVPPQPLPRRGTQPVGSLELKSACQVTAGGSSQCYRGHTNQDHVHAVWKITSEAIGQLHRSLESCPGETVVAEDP--AGLKVPLLLHQKQALAWLLWRESQKPQGGILADDMGLGKTLTMIALILTQKNQEKKEEKEKSTALTWLSKDDSCDFTSHG--------------TLIICPASLIHHWKNEVEKRVNSNKLRVYLYHGPNR-DSRARVLSTYDIVITTYSLVAKEIPTNKQEAEIPGANLNVEGTSTPLLRIAWARIILDEAHNVKNPRVQTSIAVCKLQACARWAVTGTPIQNNLLDMYSLLKFLRCSPFDEFNLWRSQVDNGSKKGGERLSILTKSLLLRRTKDQLDSTGRPLVILPQRKFQLHHLKLSEDEETVYNVFFARSRSALQSYLKRHESRGNQSGRSPNNPFSRVALEFGSEE---------PRHSEAADSPRSSTVHILSQLLRLRQCCCHLSLLKSALD-------------PMELKGEGLVLSLEEQLSALTLSELRD--SEPSSTVSLNG------------------------------------------TFFKMELFEGMRESTKISSLLAELEAIQRNSASQKSVIVSQWTNMLKVVALHLKKHGLTYATIDGSVNPKQRMDLVEAFN-HSRGPQVMLISLLAGGVGLNLTGGNHLFLLDMHWNPSLEDQACDRIYRVGQQKDVVIHRFVCEGTVEEKILQLQEKKKDLAKQVLSG-----SGESVTKLTLADLRVLFGI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P34739-1", "uniprot_id": "TTF2_DROME", "id": "P34739-1", "name": "Transcription termination factor 2", "aln": "------------------------------------------MSSENSEYYSDKEEDSVVNNSSLGRSRKSSRLSKSSRLSKSSRPSSAGVVIDETQSEE------------------------EESQSSETAESEKSDESDNSQNSQESEDSEDDSVRPSARNTKRKPLGIPSDSEDEEDE--LEQRALSPSTRMSITGVRPQDLSDDDSEIEYSDEVQEGPTEAPTAEAVVPRYTTQFAG-----------------NIQNDLHSTIGAADSEVLDDSSGSDVLILSNKETPIEILSSTDDDATTNKENMSGPP-----------FERPSKSLSPRSSAGASVVKTSKNLSQPT-----------------------------------------------IQAVLKQKTSPAAPRRSRIKSEDQKVVSQVVYDEEMRKLAEKRVQVSDAEK-----LFEKVAHKLPDKGSQIMKRIDTLRREL----------------AMDEQWISALRVQQSNVPAVRVVKPTLNPPRAPSIDTLDWDELSEAVNEIKPVYTGAQGMATFNNQKALTLESLKDLHVSLEDLPGPEVLAEDP--VGLKVSLMNHQKHALAWMSWRERKLPRGGILADDMGLGKTLTMISSVLACKNGQEMSEGKDESSDSDSEDDKNKKRKSVTGWKSKGRKDTRRGGTLVVCPASLLRQWESEVESKVSRQKLTVCVHHGNNRETKG-KYLRDYDIVVTTYQIVAREHK-----------------SLSAVFGVKWRRIILDEAHVVRNHKSQSSLAVCDLRGKYRWALTGTPIQNKELDVYALLKFLRCSPFDDLHTWKKWIDNKSAGGQNRLNLLMKSLMLRRTKAQLQSDGK-LNSLPNKELRLIEISLDKEEMNVYQTVMTYSRTLFAQFLHQRAERETDFNYRSDANKPTYNQIKDPNGAYYKMHEKFARMAGSK--KEVKSHDILVLLLRLRQICCHPGLIDAMLD----GEESQTMGDHSSDSD-TPEIDLLAQLNKLAITDTS---TDGQQSVANAGDDGPPLLPDEARIAKASKN----------------------LLKRSNPVFNLHRPSSKINMVIQILKTSILKSSDDKAIVVSQWTSVLDILRDHLSKDGVATLSLNGTIPVKNRQDIVNEFNDRNNQKRVLLLSLTAGGVGLNLIGANHLLLLDLHWNPQLEAQAQDRIYRVGQKKNVIIYKFMCVDTVEQRIKGLQDKKLDLADGVLTG------AKVSSKLTIDDLKGLFGM", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VHY2-1", "uniprot_id": "Q9VHY2_DROME", "id": "Q9VHY2-1", "name": "Transcription termination factor 2", "aln": "--------------------------------------------------------------------------MESSSPSDTTEIHKQSCSIQDQSSVP------------------------VPDSSGEINNWMEPEPVDSLELSGEYADNESAIFVSASEYNEKK---------AQIDQ--LVQKILTMEQ-------QQRQLEENASETKELCDLKLHLEKLN--------ARLEALG-----------------EFLDTLRLREDQQEIKIEDNS---------------ELVDHTEQPKWSNLYSGLNRY-----------RQKANHTAAQFYQHKSNIIDSLKTLYEPIQ----------------------------------------------PRPAIDDLEKQPALLLVRLLKHQQSCLKWMQFRERQKISGGILADDMGLGK-----TLSMIALILASEETKNRKREEKKK-------------------ALTLKWTQEFNR--------------------------------VYCKEIRKISMFDDEEESGKEEEQYEPPEKRTCHVKTKKINQFRILDDDDNDAGDKAVVEDEQKDLLAKT--------------------------------------PEPEVFSSDEEEEHLSNGRYPSAN--------------TLVVCPMSVMCQWAHEVASKVAQNAIRVLTFHGPNRHEIGIEAFRSYDLVITSYNLVVNELKRY--------------GNTSPLFAVYWNRVILDEAHIIRNSKTNCCNSVCQLRAHCHWALTGTPVQNRGVDVFALLRFVNVPNFQDLQQWKKNLN-ESMLGHRRLNFIIKPLMLRRTKQKLQASGD-MPALPSLKIELICVQLSKTEMAVYQILSAISKKIFTQFLLQREKGNSDLNYYSLERTPQFIAGHMSDERYNEIYERFLKSLGYNPGEKILGIYILVLLLRLRQFCCHPGLMIGMLRGALTAEDVQNVKVDASDVEGQLKMDVLAELDKFDETDSEDDCCDEEDSTRRDGNFKLEVIKDEIKEENVPWDSGDDLPTASSFEDQLDSARALKLLNPQNPIFQFIRPSAKLKMVIDKLEELLTG-TNDKIIVTSQWVSYLAIVRKRLQDLSWETLDFNGQLTAKEREIVLRDFN-ANNEKRVLLLSLTAGGVGLNLNVANHMLIVDLHWNPQLERQAQDRIYRYGQTKPTFIYRYMCQDTVEQRIKSLQDCKLEIAKVVLPEEGGEVTKCVGGGLNLAELKKLFEM", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . : : .. . . :. . . . . . * *: : . :..: *. : : :. . : : : : . . : . . .. * .:. . : ... . : . * *..: : *: : . : : . * . :. : :* .* *. : .**. ** * . . .. .. * **::** *:: :* *: .:* : : : .** ** . : **:*:*:*.::..* :.:: : * *:****** ::* : : . :**.*:. :**:****:**. :*:::*::*:. . *::: *:. :: * * .**.:: *.*:***** :*:: * : ** .* :.*.: * **: . : *:. : .:* :: .. . . . . : . :* ****** *** .*: . * . :.: :*. : :. : . :. * . :*: * *:*:. :: *: .:* ::.***.. * :: :* . ::* : *:* ::. ** .. :*:*:** ******** .**::::*:****.** ** ***** ** * ..:::::* .***::* **: * ::*. **. *.: :*: ** :", "identical_positions": 158, "similar_positions": 244, "identity": "12.31%" }, { "cls_id": "homologset.agr.RGD:1309146", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q969S3-1", "uniprot_id": "ZN622_HUMAN", "id": "Q969S3-1", "name": "Cytoplasmic 60S subunit biogenesis factor ZNF622", "aln": "---MATYTCITCRVAFRDADMQRAHYKTDWHRYNLRRKVASMAPVTAEGFQERVRAQR-AVAE--EESKGSATYCTVCSKKFASFNAYENHLKSRRHVELEKKAVQAVNRKVEMMNEKNLEKGLGVDSVDKDAMNAAIQQAIKAQPSMSPKKAPPAPAKEARNVVAVGTGGRGTHDRDPSEKPPRLQWFEQQAKKLAKQQ----EEDSEEEEEDLDGDDWEDIDSDEELECEDTEAMDDVVEQDAEEEEAEEGPPLGAIPITDCLFCSHHS---SSLMKNVAHMTKDHSFFIPDIEYLSDIKGLIKYLGEKVGVGKICLWCNEKGKSFYSTEAVQ---AHMNDKSHCKLFTDG-DAALEFADFYDFRSSYPDHKEGEDPNK----------------------AEELPSEK-------NLEYDDETMELILPSGARVGHRSLMRYYKQRFGLSRAVAVAKNRKAVGRVLQQYRALGWTGSTGAA----LMR-ERDMQYVQRMKSKWMLKTGMKNNATKQMHFRVQVRF--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q91VY9-1", "uniprot_id": "ZN622_MOUSE", "id": "Q91VY9-1", "name": "Cytoplasmic 60S subunit biogenesis factor ZNF622", "aln": "---MAALTCITCRVAFRDAELQRAHYKTDWHRYNLRRKVAAMAPVTAEGFQERVRAQR-AVAEAAEASKGAATYCTACGKKFATFNAYENHLGSRRHAELERKAVRAASRRVELLNAKNLEKGLGADGVDKDAVNAAIQQAIKAQPSTSPKKAPFVPTDECG---RAAAGARGVPERDPTEKPPRLQWFEQQAKKLAKQQWEDGEEEGEEEEEDDEDEDWEDIDSDDGLECED----PGVEDQDAEDAAAEESPPLGAIPITDCLFCSHHS---SSLVKNVAHMTKVHSFFIPDIEYLSDLKGLIKYLGEKVGVGKICLWCNEKGKSFYSTEAVQ---AHMNDKSHCKLFTDG-DAALEFADFYDFRSSYPDYKEGQDPAE----------------------LEALSTDK-------ILECDDETMELILPSGARVGHRSLMRYYKQRFGLPRAVTVARNQKAVGRVLQQYRALGWMGSTGAA----LMR-ERDMQYVQRMKSKWMLKIGMKNNATKQMHFRAQVRF--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VX08-1", "uniprot_id": "Q9VX08_DROME", "id": "Q9VX08-1", "name": "C2H2-type domain-containing protein", "aln": "---MSHFTCLNCDARFASADVQRNHYKTDWHRYNLKRRVAQLPPVTAEEFQQRVLSAR-SATDAALEEQNLSVYCHACRRQFASQKAHDNHLNSRKHKELLARFER------EQMTAS--------GGSASTATSVCTRSVVEQRPHPAL---------------AAAAAGKG-----------RLAFAERVVK-----------ANNDEEMVDEDDDDFEDIEEEE-------------VDSDEWDKIPEN-----PLTERDCLFCTHAS---EDLVENLKHMSVAHSFFIPDTEYCTDIEGLLYYLGEKVANYFICLFCNDRGKTFYSLDAVR---KHMIDKGHCQMLHEG-VALAEYAEYYDYSSSYPDNNEGMDID------------------------EEVVPD----------LLDGDEYQLVLPSGAVIGHRSLLRYYKQRLRPERAVVIKKSDRKLHRVLSEYRALGWTQTQQLS----AARKARDIHLMKRVQSKWQMKLGCKAN-KLQKHYRAQVLI--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38344-1", "uniprot_id": "REI1_YEAST", "id": "P38344-1", "name": "Cytoplasmic 60S subunit biogenesis factor REI1", "aln": "MSSSGVYTCNSCVLTFDSSDEQRAHMKSDWHRYNLKRRVAQLPPISFETFDSKVSAAAASTSKSAEKEKPVTKKELKRREKQALLEKKKKLLEIAR-----ANMLENMQKSQEGN------------TPDLSKLSLQENEENKEK-----------------------------------------------------------EEPKKEEP--------EQLTEEEM------------AERVMQEKLRNRV----DIPLEQCLFCEHNKHF-KDVEENLEHMFRTHGFYIPEQKYLVDKIGLVKYMSEKIGLGNICIVCNYQGR---TLTAVR---QHMLAKRHCKIPYESEDERLEISEFYDFTSSYANFNSNTTPD--------------NEDDWEDVGSDEAGSDD---EDLPQEYLYNDGIELHLPTGIKVGHRSLQRYYKQDLKPEVILTEGQ------GTLVAAETRSFLPAFDKK----GVQTQQRVWQTERFDKKRLDKR-SAKFVNNQPHYRDQLLQ--", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q06709-1", "uniprot_id": "REH1_YEAST", "id": "Q06709-1", "name": "Cytoplasmic 60S subunit biogenesis factor REH1", "aln": "-MSSTFFTCNCCVIQFKTSDLQRYHMKTEWHRYNLKRRIANLPPIGAEQFAEKLQISEKEQAENQVDEFGFPVLKPVMNQSNALPQKQKKPIKSKRGRKVGTNLLKRKDRDIAKEKQNRSVSPSGSISSQLSNLTVGTENTNTDY-----------------------------------------------------------GEDTVSEYGFTSDSNYEYATSDEE------------LDIADKPSDKENE----KITITECIYCGKDN---KEVERNVKHMFSEHGLFIPERSYLIDLNGLLEFLIKMIVIDHNCLCCNFHGS---GLESIR---AHMASKRHCRLPYETKEERQLFAPFYDFTYDDHSISKNLQNDRAITSKLSSVYGAKNDEEDGEVDITLVSSENDINANYTTVSIDESGLELTLPTGARLGHRAGQRYYRQNLPSQPNPNESR------RTITAADRRMVSGVTEKQ----YKKGMKKMQQLEKNAINTQIRR-EIKRVNFQTHYRDELLQ--", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q5FVM3-1", "uniprot_id": "RETR1_RAT", "id": "Q5FVM3-1", "name": "Reticulophagy regulator 1", "aln": "--MASPAPEEHATQGCPATEEQEPRPGVPGEEAGPEGAGPQVEEAAGRVAAALTWLLGEPVLWLGWRADELLSWKRPLRSLLAFLGANLLFWFLALTPWRVYHLISVMILGRVIMQIIKDMVLSRARGAQLWRSLSESWEVINSKPDERPR-------------------------------LSHCIAESWMNFSIFLQEMSLFKQQSPGKFCLLVCSVCTFFTILGSYIPGVILSYLLLLFAFLCPLFKCNDIGQKIYSKVKSILLKLDFGIGEYINQKKRERSEADKEKSHKDDSEIDFSALCPKISLTVAAKELSVSDTDVSEVSWTDNGTFNLSEGYTPQTDTSDDLDRPSEEVFSRDLSDFPSLENGAGTNDEDELSLG-----------------LPTELKTKKQQLNSAHRPSKDRQSAAGLSLPLKSDQALHLMSNLAGDVITAAMTAAIKDQLEGARQALAQAAPTPGDDTDTEEGDDFELLDQAELDQIESELGLTQDQGAEAQQSKKSSGFLSNLLGGH", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . :: *. : .. . . . : . * . . : . . ..: . : .: . . . . * .* : : .: . . . : . : *: . . . . * ** . : . : : .: : : : . . : :: ", "identical_positions": 8, "similar_positions": 60, "identity": "1.51%" }, { "cls_id": "homologset.agr.RGD:1309147", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9H6K4-1", "uniprot_id": "OPA3_HUMAN", "id": "Q9H6K4-1", "name": "Optic atrophy 3 protein", "aln": "MVVGAFPMAKLLYLGIRQVSKPLANRIKEAARRSEFFKTYICLPPAQLYHWVEMRTKMRIMGFRGTV-IKPLNEEAAAELGAELLGEATIFIVGGGCLVLEYWRHQAQQRHKEEEQRAAWNALRDEVGHLALALEALQAQVQAAPPQGALEELRTEL---------------------------------------------------------QEVRAQLCN----------PGRSASHAVPASKK---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q505D7-1", "uniprot_id": "OPA3_MOUSE", "id": "Q505D7-1", "name": "Optic atrophy 3 protein homolog", "aln": "MVVGAFPMAKLFYLGIRQVSKPLANRIKDAARRSEFFKTYICLPPAQLYHWVEMRTKMRIMGFRGTT-IKPLNEEAAAELGAELLGEATIFIVGGGCLVLEYWRHQTQQRNKEEEQRAAWNALQDEVGRLALALEALQAQAQAMPSLSALEELREEL---------------------------------------------------------QEVRGQVCN----------AHCTSKCQAASSKK---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AQB7-1", "uniprot_id": "A0A8I6AQB7_RAT", "id": "A0A8I6AQB7-1", "name": "", "aln": "MVVGAFPMAKLFYLGIRQVSKPLANRIKDAARRSEFFKTYICLPPAQLYHWLEMRTKMRIMGFHAEA-IKPLNEEAAAELGANLLGEAIIFATAGCCLLLEFWRQKTSKRRKEVARTATVMSLREDLDHLEDVLDEVQVQVQEALPRSTLGELRAELHTELRTELRAELQAKLRTELRAELQAE-------------------------LQAQLQEFRTQVCEDHYEPELRPEPECPETPQSKASSTLPHHTSSLP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q1L9A2-1", "uniprot_id": "OPA3_DANRE", "id": "Q1L9A2-1", "name": "Optic atrophy 3 protein homolog", "aln": "MVVGAFPIAKLLYLGVRQLSKPVANRIKAGARRSEFFKNYICLPPAQAYHWIEMRTKMRIMGFRGST-IKPLNEDAAAELGAELLGEAIIFVIGGGCMVLEYSRQAANSRRKEEELAQSITSLQTQLGELALTTETLDAQIREVN--------RLLL--------------------------------------------------------------------------------SLPAAPSSK----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VCG3-1", "uniprot_id": "OPA32_DROME", "id": "Q9VCG3-1", "name": "Putative OPA3-like protein CG13603", "aln": "MVIGVFPAAKLGILAIKQVSKPIANVIKSNAKSSPFFRKYICMPPAQFYNWVEVKTKMWALNMGGRVNVPPLNEAMAIELGANLLGEFIIFSIGAGLLIFEYSRQTIKENKKNELAQSEKMELTNMLTEMNFRLERQDAQIREMTRVLADLDSRNIFRWHKEPIQEYVPFDPDTPDQSASARNPKKFDSLYDPQGGMAFRALHFLDTQIFVDGRNRKAKEALQHLDEVAVQLEQSLGEAATVAVASSLPTKAADL-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VCG2-1", "uniprot_id": "OPA31_DROME", "id": "Q9VCG2-1", "name": "Putative OPA3-like protein CG43998", "aln": "MVIGSFPVGKIFIHGVKRISKPFGDLLIWMGKHHPFIRRYIIIPPAQLYNTFEVRSKLRMLRLKQPRRIPPLSTPVATRLGADMLSEAFVFGIGAGLIYYELSKTYTKTKKQNQEIEDQKRVLDECVDCISADVERNQREINWIKAALKNVEK-------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q0KI22-1", "uniprot_id": "Q0KI22_DROME", "id": "Q0KI22-1", "name": "OPA3-like protein CG13603", "aln": "MVVGVFPLAKLALLAIKHISKPIGNLIKQTAKKNKSFKTLVVAPPARLYHVIDVRSKMWMLGLGQPRLIPPLTDAMTIQMGGDILGEMVIFIIGATLIVGEFKRQAKNDRLKHEKHKMHREKLEERIGNLTNKVARQTKEINQLRSKLGSRETYTAY-------------------------------------------------------------------------------CNTGDLECN-----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:* ** .*: .::::***..: : .: :: : ***: *: .::::*: : : : **. : .:*.::*.* :* .. : * : . . :. * : : : . ", "identical_positions": 22, "similar_positions": 49, "identity": "8.59%" }, { "cls_id": "homologset.agr.RGD:1309148", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4AEL3-1", "uniprot_id": "D4AEL3_RAT", "id": "D4AEL3-1", "name": "", "aln": "MGSSFSSSSE--FPAQDSTAALTASSSNPPAKAAVSASSAQDPVLKNCWSCRVLSGSTLLGAGTYVYFVARRPLKQGFPPGPGTVVQMVTGIS----IACWGVIVLIDPKGKDHQDV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQ00-1", "uniprot_id": "DMAC1_MOUSE", "id": "Q9CQ00-1", "name": "Distal membrane-arm assembly complex protein 1", "aln": "MGSSFSGSTE--FSAPAPPTVSTAVPANPPAKSAVPASPARDPELKTCWSCRVLSGSTLFGAGTYVYLVARRPLKQGIPPGPGTVLQMVIGIS----IACWGVVVLVDPKGKSHPVI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96GE9-1", "uniprot_id": "DMAC1_HUMAN", "id": "Q96GE9-1", "name": "Distal membrane-arm assembly complex protein 1", "aln": "MGSRLSQPFESYITAPPGTAAAPAKPA-PPATPGAPTSPAEHRLLKTCWSCRVLSGLGLMGAGGYVYWVARKPMKMGYPPSPWTITQMVIGLSENQGIATWGIVVMADPKGKAYRVV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q9A8-1", "uniprot_id": "A0A8M9Q9A8_DANRE", "id": "A0A8M9Q9A8-1", "name": "", "aln": "------------MSNP------------APLEEKVSPQKSSRSAAGDCWSCRLLSGGGLIAAGIYVFAQVHR-RNLGKPPTVSAVLQMMFATG----LSAWGIVLIANPVGKITSK-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. .* .... : *****:*** *:.** **: .:: : * ** :: **: . . :: **:::: :* ** ", "identical_positions": 24, "similar_positions": 28, "identity": "20.51%" }, { "cls_id": "homologset.agr.RGD:1309149", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5I0H5-1", "uniprot_id": "CCNL2_RAT", "id": "Q5I0H5-1", "name": "Cyclin-L2", "aln": "--MAAAAAG-------------------------------------ASGLMAPALAACS--SGSGGAAPGSQGVLIGDRLYSGVLITLENCLLPDDKLRFTPSMSSGLDIDTETGLRVVGCELIQAAGILLRLPQVAMATGQVLFQRFFYTKSFVKHSMEHVSMACVHLASKIEEAPRRIRDVINVFHRLRHLREKKKPVPLVLDQEYVNLKNQIIKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQHLVQTAWNYMNDSLRTDVFVRFQPESIACACIYLAARTLEIPLPNRPHWFLLFGATEEEIQEICFKILQLYTRKKVDLTHLESEVEKRKHAIEEAKARAKG------LLPPGSAPGLDSATAGFSPAPKP-ESPKEGKGSKSSPLSVKNAKRKMEGPKKAKGDSPVNGLLKGQESRSQSRSREQSYSRSPSRSASPKRRKSDSGSTSGGSKSQSRSRSRSDSPPRQVHRGAPYKGSEVRGSRKSKDCKHLTQKPHKSRSRSSSRSR-SRSRERTDSSGKYKKKSHYYRDQRRERSRSYERTGHRYERDHPGHSRHRR-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JJA7-1", "uniprot_id": "CCNL2_MOUSE", "id": "Q9JJA7-1", "name": "Cyclin-L2", "aln": "--MAAAAAG-------------------------------------AAGLMAPASAACS--SGSAGAAPGSQGVLIGDRLYSGVLITLENCLLPDDKLRFTPSMSSGLDVDTETGLRVVGCELIQAAGILLRLPQVAMATGQVLFQRFFYTKSFVKHSMEHVSMACVHLASKIEEAPRRIRDVINVFHRLRHLREKKKPVPLVLDQEYVNLKNQIIKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQHLVQTAWNYMNDSLRTDVFVRFQPESIACACIYLAARTLEIPLPNRPHWFLLFGATEEEIQEICFKILQLYTRKKVDLTHLESEVEKRKHAIEEAKARAKG------LLP-GTAPGLDSA-AGFSPAPKL-ESPKEGKGGKPSPPSGKSAKRKMEGPKKAQGHSPVNGLLKGQESRSQSRSREQSYSRSPSRSASPKRRKSDSGSTSGGSKSQSRSRSRSDSPPRQVHRGAPYKGSEVRGSRKSKDCKYLTQKPHKSRSRSSSRSR-SRSRERTDNSGKYKKKSHYYRDQRRERSRSYERTGHRYERDHPGHSRHRR-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96S94-1", "uniprot_id": "CCNL2_HUMAN", "id": "Q96S94-1", "name": "Cyclin-L2", "aln": "MAAAAAAAG-------------------------------------AAGSAAPAAAAGA--PGSGGAPSGSQGVLIGDRLYSGVLITLENCLLPDDKLRFTPSMSSGLDTDTETDLRVVGCELIQAAGILLRLPQVAMATGQVLFQRFFYTKSFVKHSMEHVSMACVHLASKIEEAPRRIRDVINVFHRLRQLRDKKKPVPLLLDQDYVNLKNQIIKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQHLVQTSWNYMNDSLRTDVFVRFQPESIACACIYLAARTLEIPLPNRPHWFLLFGATEEEIQEICLKILQLYARKKVDLTHLEGEVEKRKHAIEEAKAQARG------LLP-GGTQVLDGT-SGFSPAPKLVESPKEGKGSKPSPLSVKNTKRRLEGAKKAKADSPVNGLPKGRESRSRSRSREQSYSRSPSRSASPKRRKSDSGSTSGGSKSQSRSRSRSDSPPRQAPRSAPYKGSEIRGSRKSKDCKYP-QKPHKSRSRSSSRSR-SRSRERADNPGKYKKKSHYYRDQRRERSRSYERTGRRYERDHPGHSRHRR-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W526-1", "uniprot_id": "Q9W526_DROME", "id": "Q9W526-1", "name": "Cyclin-L1", "aln": "--MATRGAGSTVVHTTVTALTVETITNVLTTVTSFHSNSVNISNNNSSSGAAPGADAAGGDAGGVAAAQADANKPIYPRLFNRIVLTLENSLIPEGKIDVTPSSQDGLDHETEKDLRILGCELIQTAGILLRLPQVAMATGQVLFQRFFYSKSFVRHNMETVAMSCVCLASKIEEAPRRIRDVINVFHHIKQVRAQKEISPMVLDPYYTNLKMQVIKAERRVLKELGFCVHVKHPHKLIVMYLQVLQYEKHEKLMQLSWNFMNDSLRTDVFMRYTPEAIACACIYLSARKLNIPLPNSPPWFGIFRVPMADITDICYRVMELYMRSKPVVEKLEAAVDELKKRYIDARNKTKEANTPPAVITVDRNNGSHNAWGGFIQRAIPLPLPSEKSPQKDS--RSRSRSRTRTHSRTPRSRSPRSRSPSRERTKKTHRSRS---SRSRSRSPPKHKKKSRHYSRSPTRSNSPHSKHRKSKSSR--ERSEYYSKKDRSGNPGSSNNLGDGDKYRNSVSNSGKHSRYSSSSSRRNSGGGGDGRSGGGGGGGGGGNGNHGSRGGHKHRDGD-RSRDRKR", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: .** ::. **. * . .*. .*. .. . * **:. :::****.*:*:.*: .*** ..*** :**..**::******:************************:****:*.** *:*:** ********************:::::* :*: *::** *.*** *:**********************:********: *::::*:* :**:**********:*: **:********:**.*:***** * ** :* .. :* :** ::::** *.* : :**. *:: *: :*: ::: ::. . ..: .** . *.* . * * :. .* .:..:. ** . . ..::. ***. *** ***.. :::** * * ....:*: *.....* *. *. .: *. *.: :* ::* *.*..:** * * .* :. * . :* . . .: * : .** :**.*: ", "identical_positions": 225, "similar_positions": 157, "identity": "39.47%" }, { "cls_id": "homologset.agr.RGD:1309150", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XI54-1", "uniprot_id": "DRC3_RAT", "id": "Q5XI54-1", "name": "Dynein regulatory complex subunit 3", "aln": "------------------------MSRPYDSMEPKVMDDDMLKVAVGEQGPQEEAGQLAKQEGI-LFKDVLALQLDFQNILRIDNLWQFENLRKLQLNNNIIERIEGLENLTHLVWLDLSFNNIEAIEGLDTLVNLEDLSLSHNRISKIDSLDPLVNLQVLSLGNNQINNMMNIIYLRRFPCLRTLSLSGNPVSEAEEY--KVFIYAYLPDLVYLDFRRVDEQAREVAKMKHQYSIDELKHREALMQIRLEEEQAKQQKLAEHKMAFVEHLNGPFLFDSMYSDDVEGNKLSYLPG-VGELLEAYKDKFVIICLNIFEYGLSQQEKRKIELDTFNECIQEAIQENQDQGKLKIAKFEEKHLLNLNAIRE------------ESDLFTMEQKLTECNESITELFNTLMILEMQLVEQLEETINVFERNITDLVGLFIENVQSLIAQCRDLENHHHEKLLEIAINTLEKILKGEMDEDLPDDVRALFVDKDTIVNAVGASHDIHLLKIDNREDELVTGVNSWCAHLVDKIHKDEIMRNRKRVKEINQFVDHMQSELDNLECGDIID----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D5E4-1", "uniprot_id": "DRC3_MOUSE", "id": "Q9D5E4-1", "name": "Dynein regulatory complex subunit 3", "aln": "------------------------MSRPYDSMEPKVMDDDMLKAAVGEQGPQEEAGQLAKQEGI-LFKDVLSLQLDFQNILRIDNLWQFENLKKLQLNNNIIERIEGLTNLIHLVWLDLSFNNIEAIEGLDTLVNLEDLSLSNNRISKVDSLDALVKLQVLSLGNNQISNMMNIIYLRRFPCLRTLSLAGNPVSEAEEY--KMFIYAYLSDLVYLDFRRVDEQMREMAKMKHQYSIDELKHREAQLQMKLEEEQAKQEKLEEHKMAFVEHLNGPFLFDSMYSEDVEGNKLSYLPG-VRELLEAYKDKFVIICLNIFEYGLNQQEKRKVELDTFNECIQEAILENQDQGKLKVAKFEEKHLLNLNAIRE------------ETDLSNIEKKLTECTESIGELFNTLMILEMQLVEQLEETINIFERNITDLVGLFIENVQSLIAQCRDLENHHHEKLLEIAINTLEKILKGEMDEDLPDDVRALFVDKDTIVNAVGASHDIHLLKIDNREDELVTGINSWCAHLVDKIHKDEIMRNRKRVKEINQFVDHMQSELDNLECGDIID----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H069-1", "uniprot_id": "DRC3_HUMAN", "id": "Q9H069-1", "name": "Dynein regulatory complex subunit 3", "aln": "------------------------MNQPCNSMEPRVMDDDMLKLAVGDQGPQEEAGQLAKQEGI-LFKDVLSLQLDFRNILRIDNLWQFENLRKLQLDNNIIEKIEGLENLAHLVWLDLSFNNIETIEGLDTLVNLEDLSLFNNRISKIDSLDALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLSLSRNPISEAEDY--KMFICAYLPDLMYLDYRRIDDHTKKLAEAKHQYSIDELKHQENLMQAQLEDEQAQREELEKHKTAFVEHLNGSFLFDSMYAEDSEGNNLSYLPG-VGELLETYKDKFVIICVNIFEYGLKQQEKRKTELDTFSECVREAIQENQEQGKRKIAKFEEKHLSSLSAIRE------------ELELPNIEKMILECSADISELFDALMTLEMQLVEQLEETINMFERNIVDMVGLFIENVQSLMAQCRDLENHHHEKLLEISISTLEKIVEGDLDEDLPNDLRALFVDKDTIVNAVGASHDIHLLKIDNREDELVTRINSWCTRLIDRIHKDEIMRNRKRVKEINQYIDHMQSELDNLECGDILD----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58IZP3-1", "uniprot_id": "A0AC58IZP3_DANRE", "id": "A0AC58IZP3-1", "name": "Dynein regulatory complex subunit 3", "aln": "-----------------------MMSGQQE--KPGVIDEQMLQRAVEEQ-------QTRNTEGIPELEELLELRLDYRNILKIYHLWSFSSLTKLQLDNNAIERIEGLENLTNLTWLDLSFNKIEVIEGLQTLVKLQDLSLFNNRISVIENLDTLQRLQVLSLGNNSIAQLENVIYLRRFQSLRTLNLAGNPICEEDRY--KTFVSAYLPELVYLDYRLLDEQTRETANAKYQYAIEEMRQNEMQEQQAMEAQKISNEELQLHKDAFVENLNGAQLFHSMFADDPDAEKLALLPG-VDALLEEFRSRMEAVCMQMFEAGLSQYSRRSAEVESFFSCSREAVAENKQKAAQIAADFESFRRLKTAEMHQ------------IQDAVQLETHLSVCRQQLTHTSEQLMSLELQLVDQLEDVYKEFERNISEMLGGFVEFVQGMFAQCRDLENQHHEQQLEIGLETLEKVLKNELEEEIPDDLAMLLVDKDTLINAANASHDTHLMKIDNREDVLRTHTDSWIKHLKTEIQEEEVKRNRKRISEIQNYIRFVKEELEDMTLPEQR-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VL65-1", "uniprot_id": "Q9VL65_DROME", "id": "Q9VL65-1", "name": "Dynein axonemal assembly factor 1 homolog", "aln": "MDEPVSSQPGEDAVEETEEEPLRGFLEEINCPEPGIIDRQMIETAYLEEGKKGEARRLHQLEPV-VYDRITTMRLEFKNILRIDHLWMMPNLTKLCLNCNKIEVIEHLEMLTALKDLNLSFNYITRIENLEKLVKLEKLSLFSNRIRKIENIHTLQNLVILSIGNNLIDTVEGIERLRFVSSLKVLNLEGNPIAKQPDFPLSLYVIAILPQLNYYEYVFIKTETREEAQKRFYRELREIEDKQEREIQGLETEAREMAEADRLASSFVEHLDGMQLYDSLWRDDEDGRILMLVGAPAQELCEEYSKDVYELTQQIYRLGLERFGERDEEIRDFNANLHEGQEELQAQGQRQIEDFLEYKERIFDEMRLKWRELDQRDDDLEQLQAQLDTLTANFEDSLNELWESLMAQELHLHEAVEDSTLKFNRKISDLMSNFVEQAQVIFLQLRDLCSYFADNMTDIVNQFLSTKLARNELNTIPEELKQCVDDREAVLQLVEGMRTTHTSRVDKREDRLAQRSRQFIDDMITNLNNKEVDRHRAKILEINSFMEMMTEALANLPGELHQEAPSD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :* ::* :*:: * :: : : * : . : ::*:::***:* :** : .* ** *: * ** ** * * * *:**** * **.*:.**:*:.*** *** ::.:..* .* :**:*** * : .: ** . .*:.*.* **:.: : . :: * *.:* * :: :. . :: *: :. : *:...: :* : . : :***:*:* *:.*:: :* :.. * : . . * * : . . : :::. **.: .*. *: * :*. * : :. .* . : :: :: .: . : ** *::* : :*: *:*:* :::. *:* .* :: * *** . . :: :* . *.. : : : :*::: . *:::::: . . : * ::*:*** * .: : .:::.*: *:* :: **:.:: : . * :: ", "identical_positions": 114, "similar_positions": 184, "identity": "20.11%" }, { "cls_id": "homologset.agr.RGD:1309151", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q4QQU6-1", "uniprot_id": "SPF30_RAT", "id": "Q4QQU6-1", "name": "Survival of motor neuron-related-splicing factor 30", "aln": "MSEDLAKQLASYKAQLQQVEAALSGNGENEDLLKLKKDLQEVIELTKDLLSTQPSETLTSSDSFASTQPTHSWKVGDKCMAVWSEDGQCYEAEIEEIDEENGTAAITFAVYGNAEVTPLLNLKPVEEGRKAKEDSGNKPMSKKEMIAQQREYKKKKALKKAQRIKELEQEREDQKVKWQQFNNRAYSKNKKGQVKRSIFASPESVTGKVGVGTCGIADKPMTQYQDTSKYNVRHLMPQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BGT7-1", "uniprot_id": "SPF30_MOUSE", "id": "Q8BGT7-1", "name": "Survival of motor neuron-related-splicing factor 30", "aln": "MSEDLAKQLASYKAQLQQVEAALSGNGENEDLLKLKKDLQEVIELTKDLLSTQPSETLASSDSFASTQPTHSWKVGDKCMAVWSEDGQCYEAEIEEIDEENGTAAITFAVYGNAEVTPLLNLKPVEEGRKAKEDSGNKPMSKKEMIAQQREYKKKKALKKAQRIKELEQEREDQKVKWQQFNNRAYSKNKKGQVKRSIFASPESVTGKVGVGTCGIADKPMTQYQDTSKYNVRHLMPQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75940-1", "uniprot_id": "SPF30_HUMAN", "id": "O75940-1", "name": "Survival of motor neuron-related-splicing factor 30", "aln": "MSEDLAKQLASYKAQLQQVEAALSGNGENEDLLKLKKDLQEVIELTKDLLSTQPSETLASSDSFASTQPTHSWKVGDKCMAVWSEDGQCYEAEIEEIDEENGTAAITFAGYGNAEVTPLLNLKPVEEGRKAKEDSGNKPMSKKEMIAQQREYKKKKALKKAQRIKELEQEREDQKVKWQQFNNRAYSKNKKGQVKRSIFASPESVTGKVGVGTCGIADKPMTQYQDTSKYNVRHLMPQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZV80-1", "uniprot_id": "SPF30_DANRE", "id": "Q7ZV80-1", "name": "Survival of motor neuron-related-splicing factor 30", "aln": "MSEELMKQLSNYKAQLQQVEAALSIDPDNEDLLKLQKDLQEVIELTKDLLTSQPAEGTTSTKSSETVAPSHSWRVGDHCMATWSQDGQVYEAEIEEIDNENGTAAITFAGYGNAEVMPLHMLKKVEEGRIRDEIDG-KPKSKKELQAEQREYKKKKAQKKVQRMKELEQEREDQKSKWQQFNNKAYSKNKKGQVKRSIFASPESVNGKVGVGTCGIADKPMTQYNDTSKYNVRHLMPQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:* ***:.************* : :*******:**************::**:* :*:.* :. *:***:***:***.**:*** *********:********** ****** ** ** ***** .* .* ** ****: *:********* **.**:*********** *******:*********************.******************:*************", "identical_positions": 187, "similar_positions": 29, "identity": "78.57%" }, { "cls_id": "homologset.agr.RGD:1309152", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q6ZQF7-1", "uniprot_id": "JADE2_MOUSE", "id": "Q6ZQF7-1", "name": "E3 ubiquitin-protein ligase Jade-2", "aln": "-----------------------------------------------------------------------------------MEEKRRKYSISSDNSDTTDGHVTSTSASRCSKLPSSTKSGWPRQ--------------NEKKPSEVFRTDLITAMKIPDSYQLSPDDYYILADPWRQEWEKGVQVPAGAEAIPEPVVRLLPPLKGPPTQMSPDSP------TLGEGAHPDWPGGS----------RYDLDEIDAYWLELLNSELK-EMEKPELDELTLERVLEELETLCHQNMAQAIETQEGLGIEYDEDVVCDVCRSPEGEDGNEMVFCDKCNVCVHQACYGILKVPTGSWLCRTCALG--VQPKCLLCPKRGGALKPTRSGTKWVHVSCALWIPEVSIGCPEKMEPITKISHIPASRWALSCSLCKECTGTCIQCSMPSCITAFHVTCAFDRGLEMRTILAD---NDEVKFKSLCQEHSD-------------------------------------------GGPRSEPTSEPVEPSQAVEDLEKVTLRKQRLQQLEENFYELVEP-AEVAERLDLAEALVDFIYQYWKLKRRANANQPLLTPKTDEVDNLAQQEQDVLYRRLKLFTHLRQDLERVRNLCYMVTRRERTKHTICKLQEQIFHLQMKLIEQDLCREPSGRRSKGK----------------------------------------------KNDSKRKGREGPKGSSPEKKEKVKAGPESVLGQLGLSTSFPIDGTFFN------------------------SWLAQSVQITAEDMAMSEWSLNSGHREDPAPGLLSEELLQDEETLLSFMRDPSLRPGDPARKARGRTRLPAKKKPSP--LQDGPSARTTPDKQPKKAWAQD---GKGTQGPP-----------------MRKPPRRTSSHLPSSPAAGDCPVPATLESPPPLASEILDKTAPMASDLNVQVPGPTVSPKPLGRLRPPREMKVSRKSPGARSDAGTGLP----SAVAERPKVSLHFDTEADGYFSDEEMSDSEVEAEDSGVQRASREAGAEEVVRMGVLAS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LGP6-1", "uniprot_id": "A0ABK0LGP6_RAT", "id": "A0ABK0LGP6-1", "name": "", "aln": "--------------------------MFPDLLISLKGNWDLSRHYHHSVCVCWPPCGPLTPIGRLLFVHVPPRGLLSKKLALWMEEKRRKYSISSDNSDTTDGHVTSTSASRCSKLPSSTKSGWPRQ--------------NEKKPSEVFRTDLITAMKIPDSYQLSPDDYYILADPWRQEWEKGVQVPAGAEAIPEPVVRILPPLKGPPTLMSPESP------TLGEGAHPDWPGGS----------RYDLDEIDAYWLELLNSELK-EMEKPELDELTLERVLEELETLCHQNMAQAIETQEGLGIEYDEDVVCDVCRSPEGEDGNEMVFCDKCNVCVHQACYGILKVPTGSWLCRTCALG--VQPKCLLCPKRGGALKPTRSGTKWVHVSCALWIPEVSIGCPEKMEPITKISHIPASRWALSCSLCKECTGTCIQCSTPSCLTAFHVTCAFDRGLEMRTILAD---NDEVKFKSLCQEHSD-------------------------------------------GGPRSEPSSEPVEPSQAVEDLEKVTLRKQRLQQLEENFYELVEP-AEVAERLDLAEALVDFIYQYWKLKRRANANQPLLTPKTDEVDNLAQQEQDVLYRRLKLFTHLRQDLERVRNLCYMVTRRERTKHTICKLQEQIFHLQMKLIEQDLCREPSGRRSKGK----------------------------------------------KNDSKRKGREGPKGSSPEKKEKMKAGPESVLGQLGLSTSFPIDGTFFN------------------------SWLAQSVQITAEDMAMSEWSLNSGHREDPAPGLLSEELLQDEETLLSFMRDPSLRPGDPARKARGRTRLPAKKKPPP--LQDGPSARTTPEKPAKKAWAQD---GKGTQGPP-----------------ARKPPRRTSSHLPSSPAAGDCPVPATLESPPTLASEILDETVPAASDLNVQVPGPTVSPKPLGRLRPPREMKVSRKSPGARSDAGTGLP----STVAERPKVSLHFDTEADGYFSDEEMSDSDVEAENRGVQRASREAGAEEVVRMGVLAS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NQC1-1", "uniprot_id": "JADE2_HUMAN", "id": "Q9NQC1-1", "name": "E3 ubiquitin-protein ligase Jade-2", "aln": "-----------------------------------------------------------------------------------MEEKRRKYSISSDNSDTTDSHATSTSASRCSKLPSSTKSGWPRQ--------------NEKKPSEVFRTDLITAMKIPDSYQLSPDDYYILADPWRQEWEKGVQVPAGAEAIPEPVVRILPPLEGPPAQASPSST------MLGEGSQPDWPGGS----------RYDLDEIDAYWLELINSELK-EMERPELDELTLERVLEELETLCHQNMARAIETQEGLGIEYDEDVVCDVCRSPEGEDGNEMVFCDKCNVCVHQACYGILKVPTGSWLCRTCALG--VQPKCLLCPKRGGALKPTRSGTKWVHVSCALWIPEVSIGCPEKMEPITKISHIPASRWALSCSLCKECTGTCIQCSMPSCVTAFHVTCAFDHGLEMRTILAD---NDEVKFKSFCQEHSD-------------------------------------------GGPRNEPTSEPTEPSQAGEDLEKVTLRKQRLQQLEEDFYELVEP-AEVAERLDLAEALVDFIYQYWKLKRKANANQPLLTPKTDEVDNLAQQEQDVLYRRLKLFTHLRQDLERVRNLCYMVTRRERTKHAICKLQEQIFHLQMKLIEQDLCR------------------------------------------------------------------------------------------GLSTSFPIDGTFFN------------------------SWLAQSVQITAENMAMSEWPLNNGHREDPAPGLLSEELLQDEETLLSFMRDPSLRPGDPARKARGRTRLPAKKKPPPPPPQDGPGSRTTPDKAPKKTWGQDAGSGKGGQGPP-----------------TRKPPRRTSSHLPSSPAAGDCPILATPESPPPLAPETPDEAASVAADSDVQVPGPAASPKPLGRLRPPRESKVTRRLPGARPDAGMGPP----SAVAERPKVSLHFDTETDGYFSDGEMSDSDVEAEDGGVQRGPREAGAEEVVRMGVLAS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7YZH1-1", "uniprot_id": "RNO_DROME", "id": "Q7YZH1-1", "name": "PHD finger protein rhinoceros", "aln": "MSQRGKRGNQQHHQSHHPPPQQHQRKDVEPQPPPTKRRKGRPPNGATTAAVAEVTGSGPATGSERVPVLPLCKSKHEEPGAEAGGGGQGRAAAGATSTSKSKSTKLAKSASKCKSQGASSSSSWQARSVADIKMSSIYNRSSTEAPAELYRKDLISAMKLPDSEPLANYEYLIVTDPWKQEWEKGVQVPVNPDSLPEPCVYVLPEPVVSPAHDFKLPKNRYLRITKDEHYSPDLHYLTNVVALAENTCAYDIDPIDEAWLRLYNSDRA-QCGAFPINATQFERVIEELEVRCWEQIQVILKLEEGLGIEFDENVICDVCRSPDSEEANEMVFCDNCNICVHQACYGITAIPSGQWLCRTCSMG--IKPDCVLCPNKGGAMKSNKSGKHWAHVSCALWIPEVSIGCVDRMEPITKISSIPQSRWSLICVLCRKRVGSCIQCSVKPCKTAYHVTCAFQHGLEMRAIIEEGNAEDGVKLRSYCQKHSMSKGKKENAGSHGGGSASVASAMQKANRYGSGAGGGADDGNNACGTTGEDPRRRKNHRKTELTSEERNQARAQRLQEVEAEFDKHVNFNDISCHLFDVDDDAIVAIYNYWKLKRKSRHNRELIPPKSEDVEMIARKQEQQDMENHKLVVHLRQDLERVRNLCYMVSRREKLSRSLFKLREQVFYKQLGVLDEMRLEKQQTKQEQQQPVMDLNAVIYANDGPTLYDRFYSSVGGQTVPAQYQDLKYILEQLMGKLQSGKQGRGRASQSPNKRKQPAKASPNKKLNNGILSSRTSSPEKTVAGSKVGTTTSKVRSPPGKNPTGRRASKSSAAAATSTHNKSQFHSNIRSSTTSHSSSGTISSGNSSSANGTSSSDSSSGSDSGSESGSSSAGSGVSKRKSSSGSPLKKQSYARSVEQRQKQRQRRQNEAVAGASATYPDSRSASSSSDGEDERCRNRQEPERGARRGPIQSKSVPNRSQASRSKPTTEADVGEGTGASARRKLSTTTRGLAQMDKDADESVSSDESEELLPLRGERQRESTTTSGLATTGSAIGRNLGQHIYSDSESSSSEQEKDQEEQATVESNVSDSQNQQTIRTKAAMKEFVPGTAATTSSTSQAASSTSKAKNTREGKEGAASIGNSTKTKPNPNAKLYPADLLVVPQRQAAKKASENMRSTNLATTLQPDVSDRVREPDINSISGTAKSKVKDSSSRVSNEADKSSLEKVRPKEHLQKTVGKTSESAPAERGKRGRPPKVPKDARPPSITENDKPALPTHTQSKPPSVVATPVSAKSNFAVSLVPQRQAAKKAAEQLKSSKPVLESFSTGNDISDKETVTSATISGSGSSVPAASTPVKPTRRSSIKEAPITPKEPLSGRRKSKEDLLATPIKTTPLVKRRVVVPNLSSSSSGDSESSSSSSSSGSSSSSGGSDSDSESQASNSENPSSREPPVAPAKVPSDSSLVPKRSPRKSMDKPSALTIAPASVNVLNIPSTRSRQNSTTKSTKVALQKAVQSVEDDVKCTPKTNRLQGSMDECGKQVQLEQATKRATRGSKSRPPSPTAKSSPEKTVSRCKSRAEESPKKVANLEQEISQRKVASGKGTSSLDKLLNKKQQQMNHSAQATPPPISPTPPASETRIVKDQCDLKPDEVSIQQINLGADAQPEPDLDPESAAEAGELPMDIDEELTTAPTRTQLSASASKLADIIDDERPPAAPLPASPTPTPTSNDEMSDAGSDLSERRRMRWRSRRRRRRRSHEPDEEHTHHTQHLLNEMEMARELEEERKNELLANASKYSASTSSPAVTVIPPDPPEIIELDSNSAEQQQQHLHDQPLPPPLVVQSPAADVVPTVMQQQLLPSQRPLIEQLPVEHLPIVETILEMEDSKFANNFASNLASVLNPPNQMSLIGSSIDRSKQISEEDSIQATRNLLEKLRKTKRKAQDDCSSKEAVDLLPPTPAIPSVFPFHNAADPEDIIHAQKEQQHQQQQQLQSSQTCIYGNSSGPNSVASLTIKDSPMTANSGSYANSLTNTPNATPTNATMNNLGYQVNFPNSQPPPTLGLFLEKSPHQKGACPLSSNGGANVGQPAPTPDFVDLAAAAVKNTLGSFRGAATVPTQSGTGVNAKINDYDESTRMQSPFGGMPWNESDLIAERRSSSPSSVSESNDPPQPPPVVTATATTARSLAQLESCKNFFNSYPSGNAGPGTAANATAPFNHPPMVNGIDSIPMFNNTNTTQHQPTTPAHQQQQQRTPNNQYNGTIYPQLAGIMHPQTTPTEPPSSLYGNGGVGGAVQSTTLPPPAQVNQYPGTPYSATTLGMISVQQPALSTVPVQTATTPNNPFTLTSPIDGKMPTYPAQLLSSCAEAVVASMMPPTPPVTATAKDSPSKRTSVSGSNLSKKQTHKSPQLPQGKSPGKSPRQPLQPPTPPAPVPVVALPPTKYDPQTHTLQGKPRQRAPRGSGGSGAPGRGRGRGRGRGRGGGVTSGMAMVLPPPMSDYGSNTHIVNNLVGTPFEFNNEFDDMAGPGVENLQSLRDRRRSFELRAPRVQNKPTTTPTTATTTNPLLHPVLPGPVDMRTYNLGFEAPHSTASQEAYQNNLLGAFDSGTADQTLSEFNEEDERQFQSALRATGTGTSPSKQHSGPTALVAPPTGPNPTPAPNLLLHCTEANQMAPNVAATGAATHLVEGSLVEASLEATSEEVSIDSDSTIPHSKTSTSDARSQIKLKIKSPMAYPEHYNAMTNSSSLTLTSTLVQSSNVVQTTVSTSTVVSASSAVSGNSRRMRKKELLSLYVVQKDNHNDDSSCGLPAASDTLPLENLRKSEEEDELSGGNGTKRFKKNSSSRELRALDANLALVEEQLLSSGAGACGGGSSGDGRRRSACSSGSNNDNNGKTGAASSAGKRRGRSKTLESSEDDHQAPKLKIKIRGLTANETPSGVSSVDEGQNYSYEMTRRACPPKKRLTSNFSTLTLEEIKRDSMNYRKKVMQDFVKGEDSNKRGVVVKDGESLIMPQPPTKRPKSSKPKKEKKEKKRQKQQQLILSSSTTTMTTTLIENTASASPGDKPKLILRFGKRKAETTTRTASLEQPPTLEAPAPLRFKIARNSSGGGYIIGTKAEKKDESTADNTSPITELPLISPLREASPQGRLLNSFTPHSQNANTSPALLGKDTGTPSPPCLVIDSSKSADVHDSTSLPESGEAAMGVQSSLVNATTPLCVNVGNYENSNNSLPSASGTGSASSNSCNSNSINNNGSGGGRASGEGGLLPLKKDCEVR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12311-1", "uniprot_id": "NTO1_YEAST", "id": "Q12311-1", "name": "NuA3 HAT complex component NTO1", "aln": "-------------------MNRGSLDDGPKLREEKHFQDFYPDLNADTLLPFIVPLVETKDNSTDTDSDDISNRNNREIGSVKSVQTKELIFKGRVTTEPLVLKKNEVEFQKCKITTNELKGKKNPY-------------CVRFNESFISRYYHINKVRNRKSYKQQQKEFDGVEAPYFTKFSSKEAPNITISTSTKSAIQKFASISPNLVNFKPQYD-------MDEQDELYLHYLN---------KRYFKDQMSHEIFEILMTTLETEWFHIEKHIPSTNSLIARHNILRDCKNYELYGSDDGTGLSMDQ--ACAVCLGTDSDNLNTIVFCDGCDIAVHQECYGIIFIPEGKWLCRRCMISKNNFATCLMCPSHTGAFKQTDTG-SWVHNICALWLPELYFSNLHYMEPIEGVQNVSVSRWKLNCYICKKKMGACIQCFQRNCFTAYHVTCARRAGLYMSKGKCT---IQELASNQFS---------------------------------------------------------------------QKYSVESFCHKHAPRGWQTSIEGINKARKYFSLLSTLQTETPQHNEANDRTNSKFNKTIWKTPNQTPVAPHVFAEILQKVVDFFGLANPPAGAFDICKYWSMKR---------------------------------------------------------------------------------------------------------------------ELTGGTPLTACFEN----------------------------NSLGSLTEEQVQTRIDFANDQLED----------LYRLKELTTLVKKRTQASNSLSRSRKKVFDIVK-------------------------------------------------------------SPQKYLLKINVLDIFIKSEQFKALERLVTEPKLLVILEKCKHCDFDTVQIFKEEIMHFFEVLETLPGASRILQTVSSKAKEQVTNLIGLIEHVDIKKLLSRDFIINDDK--IEERPWSGPVIMEEEGLSDAEELSAGEHRMLKLILNSG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . .:. . .:*. . .. : : * *. :: .* :: : *: ::.. .: .:. : :. . .* . * * :. :.: : : . : :: . : : ::* *:. *: * ** ..:.:: * :**** *::.*** **** :* *.**** * :. . *::**.: **:* . :* *.* ****:**: :. . **** :. :. *** * * :*:: *:**** * **:***** ** * : : .. . :: . :. : :: . :.: . :: : : ::. : *: : :* : .. . * : . ::* : :. *: . : :.: . : .. .. : : . ... : . : *.: : : . . . . .. : . . . : :. .: : : : . . : .:. . . . : . ", "identical_positions": 81, "similar_positions": 187, "identity": "2.5%" }, { "cls_id": "homologset.agr.RGD:1309153", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q6GMV2-1", "uniprot_id": "SMYD5_HUMAN", "id": "Q6GMV2-1", "name": "Protein-lysine N-trimethyltransferase SMYD5", "aln": "-------------------MAASMCDVFSFCVGVAGRARVSVEVRFVSSAKGKGLFATQLIRKGETIFVERPLVAAQF--LWNALYRYRACDHCLRALEKAEENAQRLTGKPGQVLP--HPELCTVRKDLHQNCPHCQVMYCSAECRLAATEQYHQVLCPGPSQDDPLHPLNKLQEAWRSIHYPPETASIMLMARMVATVKQAKDKDRWIRLFSQFCNKTANEEEEIVHKLLGDKFKG----QLELLRRLFTEALYEEAVSQWFTPDGFRSLFALVGTNGQGIG-TSSLSQWVHACDTLELKPQDREQLDAFIDQL----------------------YKDIEAATGEF-LNCEGSGLFVLQSCCNHSCVPNAETSFPENNFLLHVTALEDIKPGEEICISYLDCCQRERSRHSRHKILRENYLFVCSCPKCLAEADEPN------------------VTSEEEEEEEEEEEGEPEDAELGDEMTDV------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZII8-1", "uniprot_id": "D3ZII8_RAT", "id": "D3ZII8-1", "name": "Protein-lysine N-trimethyltransferase SMYD5", "aln": "-------------------MAASMCDVFSFCVGVAGGARGSVEVRFVSSAKGKGLFATQLIRKGETIFIERPLVASQF--LWNALYRYRACDHCLRALEKAEENAQRLTGKPGQVLP--HPELCSVRKDLHQNCPRCQVTYCSAECRLAAAEQYHQILCPGPSQDDPRHPLNKLQEAWRSVHYPPETASIMLMARMVATVKQAKDKDHWVRLFSHFCSKTANEEEEIVHKLLGDKFKG----QLELLRRLFTEALYEETLSQWFTPDGFRSLFALVGTNGQGIG-TSSLSQWVHACDALELKPQEREQLDTFIDQL----------------------YKDIEAATGEF-LNCEGSGLFVLQSCCNHSCVPNAETSFPENNFLLHVTALEDIEPGEEICISYLDCCQRERSRHSRHKILRENYLFVCSCPKCLAEADDPN------------------VTSEEEEEEDEEE-GEPEDAELGDEMTDV------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TYX3-1", "uniprot_id": "SMYD5_MOUSE", "id": "Q3TYX3-1", "name": "Protein-lysine N-trimethyltransferase SMYD5", "aln": "-------------------MAASMCDVFSFCVGVADRARGSVEVRYVDSIKGKGLFATQLIRKGETIFIERPLVAAQF--LWNALYQYRACDHCLRALEKAEENAQRLTGKPSQILP--HPELCSVRKDLHQNCPHCQVMYCSAECRLAAAEQYHQILCPGPS-HDPRHPLNKLQEAWRSVHYPPETASIMLMARMVATVKQAKDKDHWVRLFNHFCSRTANQEQAIVHKLLKGKFKD----QLELLLGLFKEALYEEALSLWFTPEGFRSLFALVGTNGQGIG-TSSLSQWVHACDALELTPQDREQLDTFIDQL----------------------YKDIEAATGEF-LNCEGSGLFVLQSCCNHSCVPNAETSFPENNFVLHVTALEDIKPGEEICISYLDCCQRERSRHSRHKILRENYLFNCSCPKCLAEADDPN------------------VTSEEEEEEDEEE-GEPEDAELGDEMTDV------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1RET2-1", "uniprot_id": "SMYD5_DANRE", "id": "F1RET2-1", "name": "Protein-lysine N-trimethyltransferase SMYD5", "aln": "-------------------MAAPVDDMFSRCVDSA-KASNCVDVRFINNVKGKGLFAKKPFKKGDTIFIERPLVSSQF--LWNALYKYRACEYCLRALETAEENARRLSGLPALILP--HPELCKVRPDRHQACPQCQVMYCSSECRQAAMDQYHKILCLGPSNDDPDHPVNKLQDAWRSVHFPPETSSVMILAKMVATIKQTQDKERWQRLFTNFCSRTANEEEEIVHKLLGEKFQG----QLGLLRNLFTTALYEDRLSQWFTPEGFRSLFSLVGTNGQGIG-TSSLSQWVHACDALELPRQQREQLDAFIDQL----------------------YKDIDKETGDF-LNCEGSGLFLLQSSCNHSCVPNAEASFPENNFLLHLTALGDIGPGEEICISYLDCCQRDRSRHSRHKILRENYLFICSCQKCLSQMDDAD------------------MTSEDEEEVEGEG--ETEGEDMEDEMTDV------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VDD0-1", "uniprot_id": "Q9VDD0_DROME", "id": "Q9VDD0-1", "name": "Protein-lysine N-trimethyltransferase SMYD5", "aln": "--------------------------------------MNNFEIRELP-GKGRAMIATKNFAKDEVIFEEEPFVSRQF--SWNVAYGYAACDHCMRPLETVLENVRRLASDPKVEVPLLQHDPTAQWVAQFTQCPRCKVRYCSEDCLMEAQKRYHRVACMGAFHSDDTHPINVLNETWKKMHYPPETGSIMLIVRLMALYQQSTKKEEFLEQLQSFQSLIVNREQKIYHKMLGENFEQ----QMEQLYLAFCNAFTGEEFSIFKTPDAFKTLMAILGTNSQGIA-TSVLSQWVAKVSDLPLTDSEKEQLDTVIDGL----------------------YAKVGEFAGEF-LNNEGSGLYLLQSKINHSCVPNACSTFPYSNDIVVLKALAPIQQGEEICISYLDECMLERSRHSRHKVLRENYVFICQCPKCRAQASDPD------------------ETSEDDDDDDEMD-----DYDDDDDMN--------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38890-1", "uniprot_id": "SET5_YEAST", "id": "P38890-1", "name": "Histone-lysine N-methyltransferase SET5", "aln": "MTLTIKIGTLNDSDQSAVHNGTENGSDFRKITPTEEEICDDVVLLWKEEPGTEDATIQHLYDRITERNQSWKLSASRFRKILNEHHLYDTDLETVSLYKDKIHFPKALDSDAKVEVKFIDDEHGRGLFAKRDFSKGQIILKENKPIVYIPPLDKLFLISNGKACARCGKALYDLTQHKIMVHYLDCEVCKAIWCSEKCKKAHASLHELLYHSWRSNRIDILHAGNWKRFVNYCEKYCFTAAFSVGLIYGSMLLDTTGEVKEQWQKLASISQRERIKLRDASGIGSTFSLLNGTTVHTEEESDNGTKKGVEKNIDDETVWEKCYELFCGAFPKASEEIDFEKFLTMIGTFNINQYNGQVYHWISFINHDCEPNAYIEQVEEHEELRLHARKPIKKGEQIRITYVNPLHGVR---LRRRELRVNWGFLCQCDRCQNELSTFERVPNLEKKNADANLGVEKIDSNDSSEDGSKKSTGNRKSSMREAQPDLKEILKNGKEFELDIPETVDTQGNVRKTSVRFDSNVSVAVDER", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . : : . : : :* * : * : : : . : * . . : . : . : . . : . * :.: * : :*: . : . :: :: . : : . :: .: : : : . : . .: : :..**. * * : . :: :: ** : .. * * :* .. :: * **.* *** .: : : * * **:* *:*:: * *:: ** *: * *.* :* : . : *::..: . : ", "identical_positions": 40, "similar_positions": 98, "identity": "7.56%" }, { "cls_id": "homologset.agr.RGD:1309154", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "O89098-1", "uniprot_id": "CYTF_MOUSE", "id": "O89098-1", "name": "Cystatin-F", "aln": "----MWLA-ILLALCCLTSDTHGAR-------------------------------PPDFCSKDLISSVKPGFPKTIETNNPGVLKAARHSVEKFNNCTNDIFLFKESHVSKALVQVVKGLKYMLEVKIGRTTCRKTMHHQLDNCDFQTNPALKRTLYCYSEVWVIPWLHSFEVPVLLCQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6ADY1-1", "uniprot_id": "A0A8I6ADY1_RAT", "id": "A0A8I6ADY1-1", "name": "", "aln": "MHTAMWLA-MLLALCCLTSDAHGAYTSGWVWSLGGSGKEYRRDAKDMESRFTASQVPRNFCSKDLNSGVEPGFPKTIKTNNPGVLKAARHSVEKFNNCTNDIFLFKESHVSKALVQVVKGLKYMLQVEIGRTTCRKTMHRQLDNCDFQTSPALKRTLHCYSEVWVIPWLHSFEVPVLRCH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O76096-1", "uniprot_id": "CYTF_HUMAN", "id": "O76096-1", "name": "Cystatin-F", "aln": "----MRAAGTLLAFCCLVLSTTGGP-------------------------------SPDTCSQDLNSRVKPGFPKTIKTNDPGVLQAARYSVEKFNNCTNDMFLFKESRITRALVQIVKGLKYMLEVEIGRTTCKKNQHLRLDDCDFQTNHTLKQTLSCYSEVWVVPWLQHFEVPVLRCH", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * ***:***. .: *. . : **:** * *:*******:**:****:***:***********:******::::****:********:*:******:*. * :**:*****. :**:** *******:***: ****** *:", "identical_positions": 97, "similar_positions": 31, "identity": "53.89%" }, { "cls_id": "homologset.agr.RGD:1309155", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U2T9-1", "uniprot_id": "FKBP5_RAT", "id": "Q5U2T9-1", "name": "Peptidyl-prolyl cis-trans isomerase FKBP5", "aln": "----MTTDEGTSNNEENPAATVVEQGEDITTKKDRGVLKIVKRVGTSEETPMIGDKVYVHYKGKLSNGKKFDSSRDRNEPFVFSLGKGQVIKAWDIGVSTMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFKGEDLFE--DSGIIRRIKRKGEGYSNPNEGATVEVHLEGCCAGRVFDCRDVVFVIGEGEDHDIPIGIDKALEKMQREEQCILYLGPQYGFGEAGKPKFGIEPNAELMYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISVCQRKAKEHNERDRRVYANMFKKFAEQDAKEEASKALSKKAVEGAAG-KKHESQTMGEGKAEGHV--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q64378-1", "uniprot_id": "FKBP5_MOUSE", "id": "Q64378-1", "name": "Peptidyl-prolyl cis-trans isomerase FKBP5", "aln": "----MTTDEGTSNNGENPAATMTEQGEDITTKKDRGVLKIVKRVGTSDEAPMFGDKVYVHYKGMLSDGKKFDSSHDRKKPFAFSLGQGQVIKAWDIGVSTMKKGEICHLLCKPEYAYGSAGHLQKIPSNATLFFEIELLDFKGEDLFE--DSGVIRRIKRKGEGYSNPNEGATVKVHLEGCCGGRTFDCRDVVFVVGEGEDHDIPIGIDKALVKMQREEQCILYLGPRYGFGEAGKPKFGIDPNAELMYEVTLKSFEKAKESWEMDTKEKLTQAAIVKEKGTVYFKGGKYTQAVIQYRKIVSWLEMEYGLSEKESKASESFLLAAFLNLAMCYLKLREYNKAVECCDKALGLDSANEKGLYRRGEAQLLMNDFESAKGDFEKVLAVNPQNRAARLQISMCQRKAKEHNERDRRVYANMFKKFAERDAKEEASKAGSKKAVEGAAG-KQHESQAMEEGKAKGHV--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13451-1", "uniprot_id": "FKBP5_HUMAN", "id": "Q13451-1", "name": "Peptidyl-prolyl cis-trans isomerase FKBP5", "aln": "----MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFKGEDLFE--DGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRMFDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQDAKEEANKAMGKKTSEGVTNEKGTDSQAMEEEKPEGHV--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QF85-1", "uniprot_id": "A0A8M9QF85_DANRE", "id": "A0A8M9QF85-1", "name": "peptidylprolyl isomerase", "aln": "MSGEMSSLEDIFSTNQCPTAVFTSRGTAVTPNGDSGVCKIVKQHGVEGERPMIGDRVFVHYTGRLLSGKKFDSSLDRKEPFVFNVGKGQVIKAWDICVCSMQKGEVCLMLCKPEYAYGSAGSPPKVPPNSTLVFEIELLNFRGEELTE--DGGIVRRIKVKGEGYSNPNEGATVHVHLEGWCGGRLFDSRDVTFAVGESEDVGVPLGVDRAMEKLQKGECCLLYLKPKYAFGKEGRKEHDIGSNAELLYEVTLKDFEKAKETWEMDLKEKLERAVLVKQKGTQYFKAGRYNYAVIQYQRIVNWLEMECGNGKEQLQAIQALLLVAHLNLALCYLRLREYSQTVENCNKVMELDPENEKALYRRGEARLLRNEFSLALMDFKQVLQVNSFNRAARSQILICQHKIREHHERDKKIYANMFQRFAEHDAKVCRLKRKKEESVISDQNKQGLKRARLSQDGS------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VL78-1", "uniprot_id": "FKB59_DROME", "id": "Q9VL78-1", "name": "FK506-binding protein 59", "aln": "----------------------MPEGNKIDLSGDGGVLKEILKEGTGTETPHSGCTVSLHYTGRLVDGTEFDSSLSRNEPFEFSLGKGNVIKAFDMGVATMKLGERCFLTCAPNYAYGAAGSPPAIPPDATLIFELEMLGWKGEDLSPNQDGSIDRTILEASDKKRTPSDGAFVKAHISGSFEGRVFEDRDVEFDYGEGKAIGIIDGVEIALEKMNVGETSRIKIQAKYAFGAKGNEEFKIPPNATVEYTVKLVDCGKGLEEWKLSDEERLAEAKVYKEKGTNYFKKENWALAIKMYTKCKNILPTTVHTN----EEVKKIKVATHSNIALCHQKSNDHFEAKQECNEVLALDKNNVKALYRRGQCNLTINELEDALEDFQKVIQLEPGNKAAANQVIICKQKLKESKNKEKKLYANMFTKLAANDKETEPPRETDVLSKCGEWSEEDAKREAELTLERDNIIMI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* : . * ** * : : * * * * * :**.* * .*.:**** .*::** *.:*:*:****:*: *.:*: ** * : * *:****:** :*.::**.**:*:*.::**:* *..: * .: .*.:** *. *:.* ** *: *** * **.: .: *:: *: *:: * . : : .:*.** *. :. * .** : * *.* . *. * *::. :*:* .* : *:*** *** .: *: * : . * . : : : :.:. *:*:*: : .:: :: : *::.: ** * *.*****:..* *::. * **::*: ::. *:** *: :*::* :* :::::::***** ::* .* : : : . . : . ", "identical_positions": 133, "similar_positions": 142, "identity": "28.6%" }, { "cls_id": "homologset.agr.RGD:1309156", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZUJ7-1", "uniprot_id": "D3ZUJ7_RAT", "id": "D3ZUJ7-1", "name": "", "aln": "MAGLGPTFPLHRLVWANRHRELEAALHSRKHDIEQEDPRGRTPLELAVTLGNLESVRVLLRHNANVGKESHQGWAVLQEAVSTGDPEMVQLVLQYRDFQRATQRLAGIPELLNKLRQAPDFYVEMKWEFTSWVPLVSKMCPSDVYRVWKRGESLRVDTSLLGFEHMAWQRGRRSFIFRGQEAGALVMEVDHDRQVVHTETLGPALHEPEVLLAAMRPSEEHVASRLTSPIVSTHLDTRNVAFERNKCGIWGWRSEKMETVSGYEAKVYSATNVELVTRTRTEHLSDQDKLRNKGGKTPFQSFLGMAQQHSSHTAAPVQQAASPTNPTAISAEEYFDPSFSLESRNIGRPIEMSSKVQRFKATLWLSEEHPLSLGDQVTPIIDLMAISNAHFAKLRDFITLRLPPGFPVKIEIPLFHVLNARITFSNLCGCDEPVSSVCVPKPSSAISASGSP--FPCEVDPTVFEVPEGYSVLGAERSEPLRDEDDDLLQFAIQQSLLEAGTEAEQVTVWEALTNTRPGIHPPPRVTVFEEQLQLEQ--ALQESLQLSTESRG---------PESPQKTPP-------PPAPP-------SFEEQLRLALELSSREQEELERRGQQEEEDLQRILQLSLTEH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PD24-1", "uniprot_id": "AN13D_MOUSE", "id": "Q6PD24-1", "name": "Ankyrin repeat domain-containing protein 13D", "aln": "MAGLGPTFPLHRLVWANRHRELEAALHSRKHDIEQEDPQGRTPLELAVTLGNLESVRVLLRHNANVGKESHQGWAVLQEAVSTGDPEMVQLVLQYRDFQRATQRLAGIPELLNKLRQAPDFYVEMKWEFTSWVPLVSKMCPSDVYRVWKRGESLRVDTSLLGFEHMTWQRGRRSFIFRGQEAGALVMEVDHDRQVVHTETLAPALHEPEALLAAMRPSEEHVASRLTSPIVSTHLDTRNVAFERNKCGIWGWRSEKMESVSGYEAKVYSATNVELVTRTRTEHLSDQDKLRNKGGKTPFQSFLGMAQQHSSHTLAPVQQAASPTNPTAISAEEYFDPSFSLESRNIGRPIEMSSKVQRFKATLWLSEEHPLSLGDQVTPIIDLMAISNAHFAKLRDFITLRLPPGFPVKIEIPLFHVLNARITFSNLCGCDEPVSSVCVPNSSSAISASGSP--FPCEVDPTVFEVPEGYSVLGAERSEPLRDEDDDLLQFAIQQSLLEAGTEAEQVTVWEALTNTRPGIHPPPRVTVFEEQLQLEQ--ALQESLQLSTESRG---------PESPQKTPP-------SPAPP-------SFEEQLRLALELSSREQEELERRGQQEEDDLQRILQLSLTEH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZTN6-3", "uniprot_id": "AN13D_HUMAN", "id": "Q6ZTN6-3", "name": "Ankyrin repeat domain-containing protein 13D", "aln": "MAGPGPTFPLHRLVWANRHRELEAALHSHQHDIEQEDPRGRTPLELAVSLGNLESVRVLLRHNANVGKENRQGWAVLQEAVSTGDPEMVQLVLQYRDYQRATQRLAGIPELLNKLRQAPDFYVEMKWEFTSWVPLVSKMCPSDVYRVWKRGESLRVDTSLLGFEHMTWQRGRRSFIFKGQEAGALVMEVDHDRQVVHVETLGLTLQEPETLLAAMRPSEEHVASRLTSPIVSTHLDTRNVAFERNKCGIWGWRSEKMETVSGYEAKVYSATNVELVTRTRTEHLSDQDKSRSKAGKTPFQSFLGMAQQHSSHTGAPVQQAASPTNPTAISPEEYFDPNFSLESRNIGRPIEMSSKVQRFKATLWLSEEHPLSLGDQVTPIIDLMAISNAHFAKLRDFITLRLPPGFPVKIEIPLFHVLNARITFSNLCGCDEPLSSVWVPAPSSAVAASGNP--FPCEVDPTVFEVPNGYSVLGMERNEPLRDEDDDLLQFAIQQSLLEAGTEAEQVTVWEALTNTRPGARPPPQATVYEEQLQLER--ALQESLQLSTEPRG---------PGSPPRTPP-------APGPP-------SFEEQLRLALELSSREQEERERRGQQEEEDLQRILQLSLTEH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AHV3-1", "uniprot_id": "A0A8M3AHV3_DANRE", "id": "A0A8M3AHV3-1", "name": "", "aln": "MA--EEAFPLHYLVWNNQYLELDRELQKKKHDLERLDPRGRSALELSVCLGHLESTRVLLRHNADPTHNNTQGWTVLQEAVSTGDPELVQLVLQYRDFRRATERLAGIPELLSKLRQARDFYVEMKWEFTSWVPLVSKVCPSDVYRVWKSGSCLRVDTTLLGFEHMTWLKGRRSYIFKGGESGAMVMEVDHEKQVVYTEPLSLSPRDAPSLLAAMLPSQENTAQRLTSPIVSTHLNTRNIAFERNKSGIWGWRSEKTEVVSGYEAKVYSASNVELVTRSRTEHLSDQDKSRSKGSRTPLQSFLGIAEQHISSTGSQVSQCASPHNPTAITAEEYFDAEFNLNGRDIGRPIELTSKVQKFKATLWLSEAHPLSLAEQVTPIIDLMAISNAHFAKLRDFITLRLPPGFPVKIEIPLFHVLNARVTFSNLCGCDEPVSSVTVQSPQGATEAGETPPPLQCEVDPSVFEPPPEYTTLGPGRSEPMRDEDDNLLQFAIQQSLLDAGTESDQVTIWEALTNTRPVSQPP----LYEEDSQLERCVAIQESLSLAGGESGESDSGPPLSPSDPALSSPPCYSSLTEPRAPGAFAVASSFDEQLRLAMELSYREQEEIDRKRREEEEELERILQLSLTEK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** :**** *** *:: **: *:.::**:*: **:**:.***:* **:***.********: ::. ***:************:*********::***:*********.***** *******************:********** *..*****:*******:* :****:**:* *:**:******::***:.*.*. : ::. ***** **:*:.*.***********:***:******.********* * ***********:*******:********** *.*..:**:*****:*:** * * : *.*.*** *****:.*****..*.*:.*:******::****:********* *****.:**********************************************:***********:*** * ...* *. .* : *****:*** * *:.** *.**:*****:***********:****::***:********* :** ::**: ***: *:****.*: * * .* :.* * .* **:******:*** ***** :*: ::**::*:*********:", "identical_positions": 424, "similar_positions": 118, "identity": "67.09%" }, { "cls_id": "homologset.agr.RGD:1309157", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZRK7-1", "uniprot_id": "D3ZRK7_RAT", "id": "D3ZRK7-1", "name": "Cell division control protein", "aln": "---------------------MPQTRSQTQATIDFPKKKQSKTLSKT------------------------------------NSRDSEVKLRNVQPVPTTPCADIKILPLSPRKRLGDDNLCNTPHLSPCSPPKLGRKENGPPRSHTRKGC------------RLIFDDEL------------------------AVKASAPKEQDRVPQHQILSS-AQRGQESETNPEQKCPPEKESACMRLFKQEGTCYQQAKLVLNTAVPDRLPAREQEMGVIRDFLKEHICGKKAGSLYLSGAPGTGKTACLSRILQDFKKEVKGFKTIVLNCMSLRNAQAVFPAIAQEIGREELCRPTGKDLMRKLEKHLTAERGPMIVLVLDEMDQLDSKGQ------DVLYTLFEWPWLSNSRLVLIGIANTLDLTDRILPRLEAREGCKPKLLNFPPYTRNQIAAILQDRLSQVSKDQVLDSAAIQFCARKVSAVSGDIRKALDVCRRAIEIVESDVRS---------QTVLKPLSECKSPCESLVPKRVGLAHISQVISGVDGNRVTLSQENTQDSLPLQQKILVCSLLLLTKRLKIKEVTLGKLYEAYSSVCRKQQ-VAAVDQSECLSLSGLLESRGIVGLKKNKES-RLTKVSLKIEEKEIEHVLKGKAFIGNILAAGLP---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O89033-1", "uniprot_id": "CDC6_MOUSE", "id": "O89033-1", "name": "DNA replication factor CDC6", "aln": "---------------------MPQTRSQTQATIGFPKKKLSNTLKKP------------------------------------NSRDCEVKLRNVQPVPTTPCVDVKLLPLSPRKRLGDDNLCNTPRLSPCSPPKLGKKENGPPRSHTWKGC------------RLVFDDEP------------------------TFKASPPKEQDRVRQHQIRSSSAQRSPESKADPEQKCPPEKESVCIRLFKQEGTCYQQAKLVLNTAVPDRLPAREQEMGVIRNFLKEHICGKKAGSLYLSGAPGTGKTACLSRILQDFKKEVKGFKSILLNCMSLRSAQAVFPAIAQEIGREELCRPAGKDLMRKLEKHLTAEKGPMIVLVLDEMDQLDSKGQ------DVLYTLFEWPWLSNSRLVLIGIANTLDLTDRILPRLEARENCKPQLLNFPPYTRNQIAAILQDRLSQVSKDQVLDSAAIQFCARKVSAVSGDIRKALDVCRRAIEIVESDVRS---------QTVLKPLSECKSPSESPVPKRVGLAHISQVISEVDGNRVTLSQENTQDSLPLQQKILVCSLLLLTRRLKIKEVTLGKLYEAYSSICRKQQ-VTAVDQSECLSLSGLLESRGLVGLKKNKES-RLTKVSLKIEEKEIEHVLNGKAFTGNILAAGLP---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99741-1", "uniprot_id": "CDC6_HUMAN", "id": "Q99741-1", "name": "DNA replication factor CDC6", "aln": "---------------------MPQTRSQAQATISFPKRKLSRALNKAK-----------------------------------NSSDAKLEPTNVQTVTCSP--RVKALPLSPRKRLGDDNLCNTPHLPPCSPPKQGKKENGPPHSHTLKGR------------RLVFDNQL------------------------TIKSPSKRELAKVHQNKILSS-VRKSQEITTNSEQRCPLKKESACVRLFKQEGTCYQQAKLVLNTAVPDRLPAREREMDVIRNFLREHICGKKAGSLYLSGAPGTGKTACLSRILQDLKKELKGFKTIMLNCMSLRTAQAVFPAIAQEICQEEVSRPAGKDMMRKLEKHMTAEKGPMIVLVLDEMDQLDSKGQ------DVLYTLFEWPWLSNSHLVLIGIANTLDLTDRILPRLQAREKCKPQLLNFPPYTRNQIVTILQDRLNQVSRDQVLDNAAVQFCARKVSAVSGDVRKALDVCRRAIEIVESDVKS---------QTILKPLSECKSPSEPLIPKRVGLIHISQVISEVDGNRMTLSQEGAQDSFPLQQKILVCSLMLLIRQLKIKEVTLGKLYEAYSKVCRKQQ-VAAVDQSECLSLSGLLEARGILGLKRNKET-RLTKVFFKIEEKEIEHALKDKALIGNILATGLP---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VSM9-1", "uniprot_id": "Q9VSM9_DROME", "id": "Q9VSM9-1", "name": "Cell division control protein", "aln": "MAAVRRSTRLSSISKATAASPLPPSTQTPRRSEVWKRRQPKKVLADSDEEEEVVTAIYDLTSPVSENNENRNVLNKMDKISRRRTSQVQVAQSELPKTPRSTKKTVQSAGSSRAKREEENREATARFLEGEQDSEVDPLHGSPPKQRKLQPLPQHLISPSRLLDRLSIDERQEEEVEATTHKTETAEQQPKHQAKDEAKPRPKQQEDPLAQKQQEKPPTKQPNKNQTKEKSNIQTNEETQQNNLPSPSRNKYQNARRVLNSAETQNLPGRESQLQELREFFSNHLESQTSGSLYVSGQPGTGKTACLSLLLRDPDFSKR-LQRVYINCTSIASVGAVYKKLCTELQLKVSGR-TERDHLEAIQRHLKTAKR-MLLLVLDEIDQLCTSRQ------EVLYTIFEWPALPGSRILLVGIANSLDLTDRALMRLNARCELKPRLMHFPPYSKQQIVEIFKSRLAEAEVLDVFPPVTLQLLAAKVSAISGDVRRALDIGRRVVEIAEQQKRDGEKEFN-MKALQLEGKDAVEAKEKQDTLKPVQVTQVAAVLNKVYGASQNLEED-IEASFPLQQKLMLCTLVLMLRNERNKDISMGRLHEVYRRVCAKRN-ILALDQAEFTGTVDLVETRGILRIMRKKEP-RLHKVLLQWDEEEVHAALSDKQLIASILSDTACLSK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P09119-1", "uniprot_id": "CDC6_YEAST", "id": "P09119-1", "name": "DNA replication factor CDC6", "aln": "---------------------------------------------------------------------------------------------------------MSAIPITPTKRIRRNLFDDAPATPP-----------RPLKRKKLQFT------------DVTPESSP-------------------------EKLQFGSQSIFLRTKALLQKSSELVNLNSSDGALPARTAEYEQVMNFLAKAISEHRSDSLYI-TGPPGTGKTAQLDMIIRQKFQSLPLSLSTPRSKDVLRHTNPNLQNLSWFELPD--GRLESVAVTSINCISLGEPSSIFQKIFDSFQDLNGPTLQIKNMQHLQKFLEPYHKKTTFVVVLDEMDRLLHANTSETQSVRTILELFLLAKLPTVSFVLIGMANSLDMKDRFLSRLNLDRGLLPQTIVFQPYTAEQMYEIVIQKMSSLP-TIIFQPMAIKFAAKKCAGNTGDLRKLFDVLRGSIEIYELEKRFLLSPTRGSLNSAQVPLTPTTSPVKKSYPEPQGKIGLNYIAKVFSKFVNNNSTRTRIAKLNIQQKLILCTIIQSLKLN--SDATIDESFDHYIKAITKTDTLAPLQRNEFLEICTILETCGLVSIKKTKCKGKTKRFVDKIDVDLDMREFYDEMTKISILKPFLH---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. : ** : : * : :. : : :. * : : : . . :. : .: . ::. : :. . : :: :.* : ... * : .... * * . . :** *: ::: : .: :: . : : :::****:*:* .: :* . *. ::*:*:**:**:.** * **: *: : * **: :*: *. .:: . :: :::: * * :. :**:*: :*: * :** * : : : : : : : . . . . .: :***:::*::: : .: ::.. .: * * : : .::: * ::*: *:: : :.* : :. : : . : .: .** ", "identical_positions": 58, "similar_positions": 154, "identity": "8.59%" }, { "cls_id": "homologset.agr.RGD:1309158", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CZP3-1", "uniprot_id": "ZN655_MOUSE", "id": "Q9CZP3-1", "name": "Zinc finger protein 655", "aln": "MEEVTSQEAAESPRGHFQPLENQSECLSPELRFLQDTDMEQGFSG-----------------------------------------------------------------------GFPISKPDGISEREQDLQVFDLESKNREVIRGDCSDGETREENKLLIPKRKISEEVHSYKVRVGKFKQDIAQVPETREVYKSEDRLERLQEILRKFLFLEREFRQITISKKTFSSEKN---TEPEKSFSLDSTLDTDQRVLRIQTTDDS-KYDMNFNQNPAVGEQEPINLTENFQSTDYKESLMDLSHLNKWESMPTTDRSYKCDTCGKTFHQASALTRHQRIHTREKPYKCKECEKSFSQSSSLSRHKRIHTREKSYKCEASDKSCDAPDKSCSQSSDVLQHKKGHAKAKSYKCGTCERVFSRSVHLTQHQRTHKDMSCKCTVCGSDFCHTSYLVEHQRLHHQEKSYEYDECGLAYVKQQGIRFQEKPYSCNECGKDFRLNSHLIQHQRIHTGEKLHECNECGKSFSQTSCLIQHHKMHRKEKSYEYNNYEESFSHSSDLTLQQEVPIRERVFDCDAWEENFSQRAHLIQHERVHTKEKPYECSELGETFSQVQASFNM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZQZ7-1", "uniprot_id": "A0A8I5ZQZ7_RAT", "id": "A0A8I5ZQZ7-1", "name": "", "aln": "MEEITSQEAAESPRVQFQSLESQSECLSPELRFLRDTEMEQGYTDAPPVPQVPALPHEGSPGDQAAALLTARYQEFVTFEDVAVHLTREEWGCLDPVQRELYREVMLENYGNVVSLGFPISKPDGISQREQDLQVFDLETQNREGVRNDCSDGETREENKLLIPKRKISEEVHSYKVRVGKFKQDIAQVPETREAYKSEDRLERLQEILRKFLFLEREFRQITISKKTFSNEKN---TEPEKSFSLDSTLDTDQRVLRIQTIDDS-KYDMNFNQNPAVGEQEPINLTENFQNTDYKESLMDLSHLNKWESMPTTDRSYKCDTCGKTFHQASALTRHQRIHTREKPYKCKECEKSFSQSSSLSRHKRIHTREKSYRCEASDKSCDASDKSCSQSSDVLQHKKVHAKAKSYKCGTCERVFSRSVHLTQHQRTHKDTACKCTVCGSDFCHTSYLVEHQRLHHQEKSYEYDECGLAYVKQQGIRFREKPYSCNECGKDFRLNSHLVQHQRIHTGEKLHECNERGKAFSQTSCLSQHHKMHRKEKSYEYNNYEESFSHNSDLTLQQEVPIRERVFDCDAWEENFSQRAHLIPHERAHTKEKPYECNELGETFSQVQASFNM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N720-1", "uniprot_id": "ZN655_HUMAN", "id": "Q8N720-1", "name": "Zinc finger protein 655", "aln": "MEEIPAQEAAGSPRVQFQSLETQSECLSPEPQFVQDTDMEQGLTG----------------------------------------------------------------------------------------------------------DGETREENKLLIPKQKISEEVHSYKVRVGRLKHDITQVPETREVYKSEDRLERLQEILRKFLYLEREFRQITISKETFTSEKNNECHEPEKSFSLDSTIDADQRVLRIQNTDDNDKYDMSFNQNSASGKHEHLNLTEDFQSSECKESLMDLSHLNKWESIPNTEKSYKCDVCGKIFHQSSALTRHQRIHTREKPYKCKECEKSFSQSSSLSRHKRIHTREKPYKCEASDKSCEASDKSCSPSSGIIQHKKIHTRAKSYKCSSCERVFSRSVHLTQHQKIHKEMPCKCTVCGSDFCHTSYLLEHQRVHHEEKAYEYDEYGLAYIKQQGIHFREKPYTCSECGKDFRLNSHLIQHQRIHTGEKAHECNECGKAFSQTSCLIQHHKMHRKEKSYECNEYEGSFSHSSDLILQQEVLTRQKAFDCDVWEKNSSQRAHLVQHQSIHTKENS-------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:.:**** *** :**.**.******** :*::**:**** :. **************:**************::*:**:*******.******************:************:**:.*** ***********:*:********. **. ****.****.* *::* :****:**.:: ***************:*.*::*****.*** ***:******************************************.*:********:*.***** **.::**** *::******.:***************: **: .****************:****:**:**:***** ****:*****:*:****:*.************:********** ***** **:******* ************* *:** ****.*** ***** *::.****.**:* ******: *: ****:. ", "identical_positions": 383, "similar_positions": 77, "identity": "62.18%" }, { "cls_id": "homologset.agr.RGD:1309162", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZWM3-1", "uniprot_id": "D3ZWM3_RAT", "id": "D3ZWM3-1", "name": "", "aln": "----MDSYFPAKNSTLAVNMNETLS--ASHGFNSTSDPPP----MSITRLFPALLECFGIVLCGYIAGRANVITSTQAKGLGNFVSRFALPALLFKNMVVLNFANVDWAFLYSILIGKASVFFVVCVLTLLVASPESRFSKAGLFPIFATQSNDFALGYPIVEALYQTTYPEYLQYIYLVAPISLMMLNPIGFIFCEIQKSKDTRNASQ-----------------------NKAKIVGLGFLRVLQNPIVFMVFVGIAFNFILDKKIPVYMENFLDGLANSFSGSALFYLGLTMVG-KIRRLKKSAFVALIVLITAKLLVLPLLCREMVEVLDKGN-SVVNHTSLSNYAFLYGVFPVAPGVAIFATQFNMEVEIITSGMVISTFVSAPIMYVSAWLLTFPTMDAKPLAYAIQNVSFDISIISLVSLIWSLSVLLLSKKYKQLPHMLTANLLIAQTIVCAGMVIWNFVKEKN-FVGQILVFVLLYSSLYSTYLWTGLLAVSLFLLKKRESVQIP--VGLIIISGWGIPALLVGVLLITG--KHNGDSVDSAFFYGKEQMITTAVTLFCSILIAG-------------------------------------VSLMCMNRTTQAGHYEGFGQSQSHKPVEPGSTAFEESPAPTSEPELFPSSIPETGCCSCSLGNGELRCPSIQPGTNSSAS------------------------------------RPRPSSFEKTDQCVSRCDSQSCILAQEEEQ------------YLQSGDPQLTRHVLLCLLLIIGLFANLSSCLWWLFNHETGRLYVELQFFCAVFNFGQGFISFGIFGLDKHLIILPFKRRLEFLWN-NKETAEDRESPVSEEIKMTCQQFVHYHRDLCIRNIVRERRCGAKTSAGTFCGCDLVNWLIEVGLASDRGEAVIYGDRLVQGGVIQHITNEYEFRDEYLFYRFLQKSPERSPPAGTVSNPPEESYKEIGHASPPSLSPKT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2AWR3-1", "uniprot_id": "LYCHS_MOUSE", "id": "A2AWR3-1", "name": "Lysosomal cholesterol signaling protein", "aln": "----MDSYFSAKNSTLAGDMNATWP--ASHGFNATGDPPS----MSITRLFPALLECFGIVLCGYIAGRANIITSTQAKGLGNFVSRFALPALLFKNMVVLNFSNVDWAFLYSVLIGKASVFFIVCVLTLLVASPESRFSKAGLFPIFATQSNDFALGYPIVEALYQSTYPEYLQYIYLVAPISLMMLNPIGFIFCEIQKSKDTQNASQ-----------------------NKAKIVGLGFLRVLQNPIVFMVFVGIAFNFILDKKIPVYMENFLDGLANSFSGSALFYLGLTMVG-KIRRLKKSAFVVLTLLITAKLLVLPLLCREMVELLDKGD-SVVNHTSLSNYAFLYGVFPVAPGVAIFATQFNMEVEIITSGMVISTFVSAPIMYVSAWLLTFPTMDAKPLAYAIQNVSFDISIISLVSLIWSLSILLLSKKYKQLPHMLTANLLIAQTIVCAGMMIWNFVKEKN-FVGQILVFVLLYSSLYSTYLWTGLLAVSLFLLKKRESVQLP--VGIIIISGWGIPALLVGVLLITG--KHNGDSIDSAFFYGKEQMITTAVTLFCSILIAG-------------------------------------VSLMCMNRTTQAGHYEGFGQSQNHKPVEPGSTAFEENPAPTNEPELFPSSIPETSCCSCSLGNGELRCPSIEPVTNSSAS------------------------------------GPMPSSFEKTDHCVSRCDSQSCILAQEEEQ------------YLQSGDPQLTRHVLLCLLLIIGLFANLSSCLWWLFNHETGRLYVELQFFCAVFNFGQGFISFGIFGLDKHLIILPFKRRLEFLWN-NKEAAADRESPVSEEIKMTCQQFVHYHRDLCIRNIVRERRCGAKTSAGTFCGCDLVNWLIEVGLASDRGEAVIYGDRLVQGGVIQHITNEYEFRDEYLFYRFLQKSPEQSPPARTLRDHQEESYKEIGHSSPPSVSPKT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z3F1-1", "uniprot_id": "LYCHS_HUMAN", "id": "Q7Z3F1-1", "name": "Lysosomal cholesterol signaling protein", "aln": "----MNSNLPAENLTIAVNMTKTLPTAVTHGFNSTNDPPS----MSITRLFPALLECFGIVLCGYIAGRANVITSTQAKGLGNFVSRFALPALLFKNMVVLNFSNVDWSFLYSILIAKASVFFIVCVLTLLVASPDSRFSKAGLFPIFATQSNDFALGYPIVEALYQTTYPEYLQYIYLVAPISLMMLNPIGFIFCEIQKWKDTQNASQ-----------------------NKIKIVGLGLLRVLQNPIVFMVFIGIAFNFILDRKVPVYVENFLDGLGNSFSGSALFYLGLTMVG-KIKRLKKSAFVVLILLITAKLLVLPLLCREMVELLDKGD-SVVNHTSLSNYAFLYGVFPVAPGVAIFATQFNMEVEIITSGMVISTFVSAPIMYVSAWLLTFPTMDPKPLAYAIQNVSFDISIVSLISLIWSLAILLLSKKYKQLPHMLTTNLLIAQSIVCAGMMIWNFVKEKN-FVGQILVFVLLYSSLYSTYLWTGLLAISLFLLKKRERVQIP--VGIIIISGWGIPALLVGVLLITG--KHNGDSIDSAFFYGKEQMITTAVTLFCSILIAG-------------------------------------ISLMCMNQTAQAGSYEGFDQSQSHKVVEPGNTAFEESPAPVNEPELFTSSIPETSCCSCSMGNGELHCPSIEPIANTSTS------------------------------------EPVIPSFEKNNHCVSRCNSQSCILAQEEEQ------------YLQSGDQQLTRHVLLCLLLIIGLFANLSSCLWWLFNQEPGRLYVELQFFCAVFNFGQGFISFGIFGLDKHLIILPFKRRLEFLWN-NKDTAENRDSPVSEEIKMTCQQFIHYHRDLCIRNIVKERRCGAKTSAGTFCGCDLVSWLIEVGLASDRGEAVIYGDRLVQGGVIQHITNEYEFRDEYLFYRFLQKSPEQSPPAINANTLQQERYKEIEHSSPPSHSPKT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B2E6-1", "uniprot_id": "A0A8M3B2E6_DANRE", "id": "A0A8M3B2E6-1", "name": "", "aln": "----MEDLLGNVSVSSRDES------------GAPTVPPS----MSIDKLLPALLECFGIILCGYVAGRTNIILATQAKGLGSFVSKFALPALLFKNMVLLDFGDVIWPFFFSILVAKVTVFFFVCVLTLLVGNRESRYSKAGLFPIFATQSNDFALGFPIVEALYRSTHPEYLQYIYLVAPVSLMVLNPLGFMFCEVQRRKNGEPSQQ-----------------------SKLHVLGLVVLQVFKNPIVFMVMIGLVSHFLLCQKIPAFMEQFVDGLANSFGGAALFYLGLSMVG-QLKKLTRTTVVALILLITAKLLMMPLICRGMVEVLDNTNRSTLNHTSLSNYAFLYGVFPTAPSVAIYAAHYNMELEVVTSGMVVSTFLSAPIMYVSAWLLTIPWMDSAPLASALQNVSFDISIISLFALVWSLTVMILSRKYHRIPHIFTINLFVAQLLVCVGMIVWNFVVKQDSFVAQVLSFTLLYGSLYSTYIWPGLIVLSLLLMRS-EEVNFR--PGLTVITGWGLPFLAVSVLLLSG--HRMPDTIDSAFFYGTTQVMCTSVVLCVSIAVCG-------------------------------------VSLALLSRRTQD--YQNLVSGSLSGSEEDLRIPYN-APVQGSIEDTCTLGSTNTACQMC-------ECACALPQTRPDVT------------------------------------NTKEEVSIQTGQCGQECTSTHCLLVEEEEKET----------ERQNTDIQSTRHVLMCLILTVTSLANLCSCLWWLFNKDPGRLYLELQFFCVVANYGQGLISFAFFGLDKHLIISPFKKRLESVWQ-WWAQLVS-GSEVSEEIRLTCNQFLKYHKKQCIKDIVHKKRCGEKSSIQAFLGTDMVVWLQSVGLASDQGEAVLYGSRLLDGGVIQHITQQHAFEDQTLHYRFT------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9PFK5-1", "uniprot_id": "M9PFK5_DROME", "id": "M9PFK5-1", "name": "", "aln": "MDSSMYYASQRIAASTEANVRVITSTMASSLANGTATPRADDGGVSMNNFYPALVQCFGIIICGYIAGRFKIISNAETKGLGTFVGTFALPSLIFLSLVELNWSAVNWSFLLAMLVSKAVVFFAVLIISLLVARPLN-YARGGLMAIFCTQSNDFAIGYPIVMALYKDVHPEYASYLYLMAPISLAILNPVGLVLMEISKIIKNKEDVTRNPPLCPETCPAEQMSKRNRCLGERSILVFNTLIALFFNPLLLMTLLGVAGGFLFPNGLPEMVSSTLRVLGQSFSATALFLLGLKIVGGTGSERKSIGFLLPGVLILVKILVLPLVIRQTVNIMQSGQ-NFNDTTELSTFGFLYGTFPAAPGAFVIATQYNMEVELVARSMVFCTFISAPLMFISAKMISLTNLKPLDYLHELDAFSFDISVAGAAACCIMLALLIVTKRFKRMPQRITFCLVLSQLMCCIGVILWSKMEHVH-RWPLYLQFLLFNIGTYSTRLWTGLLAISLLFLQCRSLCFVLKLWPYMLVFAWGVPAVLSALLIAFDSNVMSGEKHNPSFQYGNAQAAISVFMLVMCFIVTVGCLVLHQRYKKRYEKYMTYSRELSNPESESSDLHSTISTTNLLSHTDQSSIRQSVRTASYSSSSDDEEMIPTAAGLPTSRSNGAASGGAGSGGGGCGSGNG-TCCSGGAPVSNSSTTSTVVVDIEDLLNRTRQRASGANNKDLNKIESAPATEEIRNQMCSSSFNCGPSTSRQSCQTIIERYEDQNRRGLEPLEHPSDADEHQTLKHTVLLITLLCSMFVGLAVSIWTLVMEGMSGIYLELSFLDAFLNFGQGLIVLAVFITDIGELLMPVVKLWRKLWYGANVVSLPHWSNVRPETKHICEQFRNHHLENCKKDIAKDRRWRIRVYRRVFYGTEFVSWLIEVGLSKDRMEAVHYARHLVDGRVLRHINNVYHFEDKLLLYNFCSRI---------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : : ... * . :*: .: ***::****::***:*** ::* :::****.**. ****:*:* .:* *::. * *.*: ::*:.*. *** * :::***. . :::.**:.**.*******:*:*** ***: .:*** .*:**:**:** :***:*::: *:.: . . .: :: .: :: **:::*.::*:. *:: . :* :.. : *.:**..:*** ***.:** . . .: :** .*:*::**: * *::::. : . : *.**.:.****.**.**.. : *:::***:*::: .**..**:***:*::** ::::. :.. :: .*****: . : *::::::::::::*: :* *.::* : * *:::*. : . . * * *: . *** :*.**:.:**:::: . . :: .**:* : .:*: . :. :.:* **. * : . * .: : : :.: * :.. .. : . : . . . :. * *. * :....: .. :* * *. : : : * :*.:: : * :..*. .:* *. . . :*:**.*: .. *:***:* :..* * :: *. : . :* * * * : *:** ::* . * ::*.:.:* : .* * ::* ** .***:.*: *** *. :*::* *::**.: : *.*: * *.* ", "identical_positions": 219, "similar_positions": 304, "identity": "22.03%" }, { "cls_id": "homologset.agr.RGD:1309163", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "F1LUS2-1", "uniprot_id": "F1LUS2_RAT", "id": "F1LUS2-1", "name": "Protein argonaute-3", "aln": "MEIGSAGPIGAQPLLIVPRRPGYGTMGKPIKLLANCFQVEIPKIDVYLYEVDIKPDKCPRRVNREVVDSMVQHFKVTIFGDRRPVYDGKRSLYTANPLPVATTGVDLDVTLPGEGGKDRPFKVSVKFVSRVSWHLLHEVLTGRTLPEPLELDKPISTNPVHAVDVVLRHLPSMKYTPVGRSFFSAPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIQFMCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQTFPLQLENGQTVERTVAQYFREKYTLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYETDPFVQEFQFKVRDEMAHVTGRVLPAPMLQYGGRSLSSLLQNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVVQKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHVSGQSNGRDPQALAKAVQIHQDTLRTMYFA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CJF9-1", "uniprot_id": "AGO3_MOUSE", "id": "Q8CJF9-1", "name": "Protein argonaute-3", "aln": "MEIGSAGPIGAQPLFIVPRRPGYGTMGKPIKLLANCFQVEIPKIDVYLYEVDIKPDKCPRRVNREVVDSMVQHFKVTIFGDRRPVYDGKRSLYTANPLPVATTGVDLDVTLPGEGGKDRPFKVSVKFVSRVSWHLLHEALAGGTLPEPLELDKPVSTNPVHAVDVVLRHLPSMKYTPVGRSFFSAPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIQFMCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQTFPLQLENGQTVERTVAQYFREKYTLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYETDPFVQEFQFKVRDEMAHVTGRVLPAPMLQYGGR-------NRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVVQKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDDNFFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHVSGQSNGRDPQALAKAVQIHQDTLRTMYFA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H9G7-1", "uniprot_id": "AGO3_HUMAN", "id": "Q9H9G7-1", "name": "Protein argonaute-3", "aln": "MEIGSAGPAGAQPLLMVPRRPGYGTMGKPIKLLANCFQVEIPKIDVYLYEVDIKPDKCPRRVNREVVDSMVQHFKVTIFGDRRPVYDGKRSLYTANPLPVATTGVDLDVTLPGEGGKDRPFKVSIKFVSRVSWHLLHEVLTGRTLPEPLELDKPISTNPVHAVDVVLRHLPSMKYTPVGRSFFSAPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIQFMCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQTFPLQLENGQTVERTVAQYFREKYTLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYETDPFVQEFQFKVRDEMAHVTGRVLPAPMLQYGGR-------NRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVVQKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHVSGQSNGRDPQALAKAVQIHQDTLRTMYFA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3ATW3-1", "uniprot_id": "A0A8M3ATW3_DANRE", "id": "A0A8M3ATW3-1", "name": "Protein argonaute-3", "aln": "MEIGTTGAVGAQSLFSMPRRPGYGTMGKPIKLLANCFQVEIPKMDVYLYEVDIKPEKCPRRVNREVVDSMVQHFKVTIFGDRRPVYDGKKSLYTANPLPVAPAGVDLDVTLPGEGGKDRPFKVSIKFVSLVSWHLLHEVLTGRSMPEPLELDKPISTNPVHAVDVVLRHLPSMKYTPVGRSFFSAPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIQFMCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQTFPLQLENGQTVERTVAQYFREKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYEADPFVQEFQFKVRDEMAHVTGRVLPAPMLQYGGR-------NRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEVIQDLSSMVRELLIQFYKSTRYKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKEYQPGITYIVVQKRHHTRLFCADRNERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDDNCFTADEFQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHVSGQSNGRDPQALAKAVQIHHDTLRTMYFA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A3KPK0-1", "uniprot_id": "AGO3_DANRE", "id": "A3KPK0-1", "name": "Protein argonaute-3", "aln": "MEIGTTGAVGAAPQFSVPRRPGYGTMGKPIKLLANCFQVDIPKMDVYLYDVDIKPEKCPRRVNREVVDSMVQHFKVTIFGDRRPVYDGKKSLYTAQPLPVASAGVDLDVTLPGEGGKDRIFKVTIKFVSLVSWHMLHEVLTGRSTPDPLELDKPISTNPVHAVDVVLRHLPSMRYTPVGRSFFSSPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIQFMCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQTFPLQLENGQTVERTVAQYFREKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYNSDPFVQEFQFRVRDEMAEVTGRVLPAPMLQYGGR-------NRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEVLKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADNVEPMFRHLKNTYAGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEVIQDLASMVRELLIQFYKSTHYKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKEYQPGITYIVVQKRHHTRLFCADRAERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYYVLWDDNCFTADEFQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHVSGQSNGRDPQALAKAVQIHHDTLRTMYFA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****::*. ** . : :**********************:***:*****:*****:*********************************:*****:*****.:**************** ***::**** ****:***.*:* : *:*******:******************:**********:************************************************************************************************************************************.***********************************************************************::*********:******.**************** ******************************************:*********************************.************:***************************************:************************************************************************************:****:**************::*************************************:*********************** ********************************************:****** *****:**********************************************************************:*********", "identical_positions": 809, "similar_positions": 41, "identity": "93.31%" }, { "cls_id": "homologset.agr.RGD:1309164", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5I0K8-1", "uniprot_id": "RT07_RAT", "id": "Q5I0K8-1", "name": "Small ribosomal subunit protein uS7m", "aln": "MAAPALRAARRWSGLALGVRCAVWNLPGITQVRWSRYAPEFRDPLIDKEHYRKQVSELTEEEKYDLELKKTQLIKAAAATETSSVFADPVISKFTNMMMKGGNKVLARSLMAQTLEAVKRK-------QFEKYRAASAEEQATIER------------NPYKIFHEALRNCEPVIGLVPILKG-GHFYQVPVPLADRRRRFLAMKWMITECRENKPRRMLMPEKLSHELLEAFHNRGPVIKRKHNMHKMAEANRALAHYRWW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80X85-1", "uniprot_id": "RT07_MOUSE", "id": "Q80X85-1", "name": "Small ribosomal subunit protein uS7m", "aln": "MAAPALRAPLRWSGLALGVRCAVWNLPGLTQVRGSRYAPEFREPLIDKEYYRKPVAELTEEEKYDQELKKTQFIKAAAATETSSVFADPVISKFTNMMMKGGNKVLARSLMAQTLEAVKRK-------QFEKYRAASAEEQATIER------------NPYRIFHEALKNCEPVIGLVPILKG-GHFYQVPVPLADRRRRFLAMKWMITECRENKPRRTLMPEKLSHELLEAFHNRGPVIKRKHNMHKMAEANRALAHYRWW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y2R9-1", "uniprot_id": "RT07_HUMAN", "id": "Q9Y2R9-1", "name": "Small ribosomal subunit protein uS7m", "aln": "MAAPAVKVARGWSGLALGVRRAVLQLPGLTQVRWSRYSPEFKDPLIDKEYYRKPVEELTEEEKYVRELKKTQLIKAAPAGKTSSVFEDPVISKFTNMMMIGGNKVLARSLMIQTLEAVKRK-------QFEKYHAASAEEQATIER------------NPYTIFHQALKNCEPMIGLVPILKG-GRFYQVPVPLPDRRRRFLAMKWMITECRDKKHQRTLMPEKLSHKLLEAFHNQGPVIKRKHDLHKMAEANRALAHYRWW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q498Z6-1", "uniprot_id": "RT07_DANRE", "id": "Q498Z6-1", "name": "Small ribosomal subunit protein uS7m", "aln": "MAASVRHLLKPWT-------------PSLCLMRWSRYNPYYLDPEPRKDAP-VSDSELSPEQKELQELKTVRPIKAALTGDTSSAFSDPLISKFINMMMYDGNKVLARGIMTQTLETIKRK-------QVEKYHKSPAAKREEIEC------------NPYAIFHQAMENCKPVIGLASIQKG-GKFYQVPVPLTDNRRRFMAMKWMITECRTNKQGRTLMYEKLSQELLAAFANEGNVIKRKHDLHKMAEANRAYAHYRWW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VKX4-1", "uniprot_id": "RT07_DROME", "id": "Q9VKX4-1", "name": "Small ribosomal subunit protein uS7m", "aln": "MSLLGRIAEKTSR------------LSCLRLM--SVYPTHYVEPIVQKYKQLEQKNDLS-------KLYHVP-IKAAVNKSSDTIFHDDTKHKMINYITKKGNSALARTLLSKTLELIKRT-------QTEHMNLAKGEK-TTINT------------NPETLLKQAVENCRPLLQVTAIKRG-GVTYQVPVPITTKRSYFLAMKWLLEAARE-KERKVSLPEKLAWEILDAAHGQGRVIKRKDDLHRLCESNRAYAHYRWS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P47150-1", "uniprot_id": "RT07_YEAST", "id": "P47150-1", "name": "Small ribosomal subunit protein uS7m", "aln": "MLHCARRYMLVRP-----------RLLWQSGTCVARFQSSVRTPASEPSAEKGVDEWLEAINELREEFSAKEYLPETSLAPPGQSKVDLLQGSQAGSKIKPTAEQLAQWEALKSVPIPPRKNATLDHITNMIMRHGKKEKAQTILSRALYLVYCQTRQDPIQALEKSLDELAPLMMTKTFNTGVAKASVIPVPLNKRQRNRIAWNWIVQSANQRVSSDFAV--RLGEELTAIAKGTSSAFEKRDQIHKTAIAHRAYIQLK--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : : . * * :: : : .. * . . . **: ::: *. . . : * :* :.::: : *:: .: * . :***: .: :* :*:: .. : :*. :: . . .::::.::*: . ::** : : ", "identical_positions": 20, "similar_positions": 63, "identity": "7.63%" }, { "cls_id": "homologset.agr.RGD:1309165", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5BJQ1-1", "uniprot_id": "Q5BJQ1_RAT", "id": "Q5BJQ1-1", "name": "Claudin", "aln": "MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTGIYQCQIYRSLLALPRDLQAARALMVISCLLSGMACACAVVGMKCTRCAKGTPAKTTFAVLGGALFLLAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTLLCLSCQDEG-----PYRPYQPQSRAGATTTATAPAYRPPAAYKD------NRAPSVTSAAHS--------------------GYRLNDYV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z0S3-1", "uniprot_id": "CLD14_MOUSE", "id": "Q9Z0S3-1", "name": "Claudin-14", "aln": "MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTGIYQCQIYRSLLALPRDLQAARALMVISCLLSGMACACAVVGMKCTRCAKGTPAKTTFAVLGGALFLLAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTLLCLSCQDEA-----PYRPYPPQSRAGATTTATAPAYRPPAAYKD------NRAPSVTSAAHS--------------------GYRLNDYV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95500-1", "uniprot_id": "CLD14_HUMAN", "id": "O95500-1", "name": "Claudin-14", "aln": "MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTGIYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAILGGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTLLCLSCQDEA-----PYRPYQAPPRATTTTANTAPAYQPPAAYKD------NRAPSVTSATHS--------------------GYRLNDYV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BHN3-1", "uniprot_id": "A0A8M2BHN3_DANRE", "id": "A0A8M2BHN3-1", "name": "", "aln": "MAILALELMGFFFGLIGMLGTLVATLLPYWATSAHVGPNIVTAVVSMKGLWMECVYQSTGAFQCETYNTLLGLTVDLQAARAMMVMSSIFSVMACAVSTVGMQCTVCMDGSSVKTKVAGVGGSMFLLAGLLSLIPVAWKTHEVVQTFYMPNMPASLKFEIGDCLYVGLASSLLSMLGGGLLSASCCDDIDGNRGSRRHYPYPERNALRGPSHSMTYQPAALHSTTNPNITNKTQTLNSHTSSGTHSIQAQDSRKMTRQNTAAGYDVTGYV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** *::*:**::.::**:***::*:**:* :****.**:*** :********::*** :**: *.:**.*. *******:**:*.::* :*** :.:**:** * .*:..**..* :**::*:*****.::.*:*.*::***.** * :*:.:*****:.**:*: ** **::** **. ** *: . * * * . : :*:*.* :. *:: ::.* : * ** :..**", "identical_positions": 114, "similar_positions": 83, "identity": "42.22%" }, { "cls_id": "homologset.agr.RGD:1309166", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "C3VPR6-1", "uniprot_id": "NLRC5_MOUSE", "id": "C3VPR6-1", "name": "Protein NLRC5", "aln": "MDAESIRLNNENLWAWLVRLLSKNPEWLSAKLRSFLPTMDLDCSYEPSNPE-VIHRQLNRLFAQGMATWKSFINDLCFELDVPLDMEIPLVSIWGPRDEFSKQLGAGEESCPGPQLYHGAKRPFQSYGSSPRRKNSKKQQLELAKKYLKLLKTSAQQWHGGVCPGAWLTPHSPQTYIPPVLQWSRATAPLDAQEGATLG-DPEAADNIDVSIQDLFSFKAHKGPRVTVLLGKAGMGKTTLAYRLRWRWAQGQLDRFQALFLFEFRQLNMITQLPTLPQLLFDLYLMPESE-PDAVFQYLKENAQEVLLIFDGLDEALHADSVGTDNAGSALTLFSELCHGNLLPGCWVMTTSRPGKLPSCVPTEAATVHMWGFDGLRVEKYVTCFFSDLLSQELALKEMRTNARLRGMCAIPALCTVTCFCLRR-LLPGSSPGQSAALLPTITQLYLQMVETFSPSETLLDTSILGFGKVALRGLDTGKVVFSVEDISPQLMSFGAVHSLLTSFCIHTRPGHEEIGYAFVHLSLQEFFAALYLMASHTVDKDTLVEYVTLNSHWVLRTKGRLGLSDHLPAFLAGLASHTCHMFLCQLAQQDRAWVGSRQAAVIQVLRKLASRKLTGPKMIELYHCVAETQDLELARFTAQSLPSRLSFHNFPLTHADLAALANILEHRDDPIHLDFDGCPLEPHCPEALVGCGQVENLSFKSRKCGDAFAEALCRSLPTMGSLKTLGLTGSRITAQGISHLIQTLPLCSQLEEVSLHDNQLKDPEVLSLVELLPSLPKLQKLDLSRNSFSRSILLSLVKVAITCPTVRKLQVRELDLIFYLSPVTETATQQSGASDVQGKDSLKEG-QSRSLQLRLQKCQLRIRDAEALVELFQKSPQLEEVNLSGNHLEDDGCRLVAEAASQLHIAQKLDLSDNGLSQTGVTYVLKAMSTCGTLEDLHISLLNNTVVLTFAQEPREQEGSCKGRAPLISFVSPVTSELSQRSRRIRLTHCGFLAKHTETLCEALRASCQTHNLDHLDLSDNSLGGKGVILLTELLPGLGPLKSLNLSRNGLSMDAVFSLVQCLSSLQWVFHLDVSLESDCIFLRGAGTSRDALE----PKFQTGVQVLELSQRYTSRSFCLQECQLEPTSLTFLCATLEKSPGPLEVQLSCKSLSDDSLKILLQCLPQLPQLSLLQLRHTVLSSRSPFLLADIFNLCPRVRKVTLRSLCHAVLHFDSNEEQEGVCCG-FPGCSLSQEHMETLCCALSKCNALSQLDLTDNLLGDIGLRCLLECLPQLPISGWLDLSHNNISQEGILYLLETLPSYPNIQEVSVSLSSEQIFRMCFSKKEGAGTSLRLCECSFSPEQVSKLASSLSQAQQLTELWLTKCHLDLPQLTMLLNLVNRPTGLLGLRLEEPWVDSVSLPALMEVCAQASGCLTELSISEIQRKLWLQLEFPHQEGNSDSMALRLAHCDLETEHSHLMIQLVETYARLQQLSLSQVSFNDNDGTSSKLLQNILLSSCELKSFRLTFSQVSTKSLTHLAFGLGHCHHLEELDFSNNSLREEDTELLMGALQGTCRLKKLHLSFLPLGASSLALLIQGLSRMTLLQDLCLSHNQIGDVGTQCLAAILPKLPELRKFDLSHNQIGDVGTQCLAAILPKLPELRKFNLSHNQIGHVGTQCLAAILPKLPELRKFDLSRNQIGDVGTQCLAAILPKLPELRKFDLSGNRIGPAGGVQLVKSLTHFEHLEEIKLGNNALGEPTALELAQRLPPQLRVLCLPSSHLGPEGALGLAQALEQCPHIEEVSLAENNLAGGVPRFSKRLPLLRQIDLEFCKIEDQAARHLAANLTLFPALEKLLLSGNLLGDEVAAELAQVLPQMGQLKKVNLEWNRITARGAQLLAQGLVQGSCVPVIRLWNNPILNDVAQSLQSQEPRLDFSITDQQTL-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0M751-1", "uniprot_id": "A0ABK0M751_RAT", "id": "A0ABK0M751-1", "name": "Protein NLRC5", "aln": "MDAESYRLGNENLWAWLVELLSKKPEWLSAKVRFFLPTLDPDCSNEAPISE-VTHHQLNRLFAQGPATWESFIYTLCIELEVPLSLEVPLLSIWGQKDEFSKQLGACEESHPGPELHHGVKRPFQSYGSSPRRKHSRKQQLELVKKYLKLLRTSAQQCHGGQCPGAWNARDSPQTYIPPIVQWSGTSAPLDAQEGARIGGDPEAADSTDVSIHDLFNFKAHKGPRVTVVLGKAGMGKTTLAHRLHWRWAHGQLDRFQAVFLLEFRQLNMITQLLTLPQLLFDLYLSPESDDADAVWQYLEENAHQILLIFDGLDEALHTDSVGTDNAGSALTLFSELCHGDLLPGCWVMTTSRPGKLPSCVPTEAAMVYMWGFDGLRVEKYVTHFFSDLLSQELALKEMRANERLRGMCAIPALCRVACFCLRCSLLSGSSPGQSSALLPTITQLYLQMVKTFSSSGTLSATSLLGLGNVALRGLVTGKVIFSVEDIPPQLMALGAVHSLLTSFCIRTRSGHKEIGYAFVHLNLQEFFAALYLMASDTVDKDTLINYVTLNSHWVLRTKAKPGLSDHLPTFLAGLASHTCHTFLCHLAQQDEAWVGSRQATVIQVLRKLASRKLTGPKMVELYHYVAETQDLELARFVAQSLPFDLSFHNFPLTRADLASLANILEHRDGPIHLDFDGCPLEPHCPEALVGCGQVENLSFKSRKCGDAFAEALCRSLPTMGSLKMLGLTGSKITAQGISHLIQALPLCSQLEEVSLHDNQLKDPEVLSLVDLIPCLRKLQKLDLSQNSFCMSTLLSSVKAAITCPTVRKLQVRESELIFFLSPVPETATQQSGASDAQGEDSPKEG-QSRNLQLRLQKCQLRVHDAKALVELFQKGPRLEEVDLSGNHLKDEGCRLVTKAVSQLHIAQKLDLSDNGLSQTGVTYLLKAVSTCGTLEELHISLLTNTVVLTFAQELRDQEGSFKRGAQLTGFMSPVTSELSQRSRRIRLTHCGFLAEHTEKLCEALRVSCQSHPLDHLDLSDNFLKDKGVILLTQLLPRLGPLKSLNLSRNDFSMDAVFSLVLCMSSLQWLFHLEVSLESDCIFLRGAGTSRDALAGG--PEFPAGAQLLELSQRCTSRSFCLQECQLESLNLAYLCDALEKCPGPLEIQLSCKSLNDDSLKTLLQRLPQIPQLSQLRLTHTVLSSRSPFLLADIFNLCPWVQKVNLRSLSHAVLHFNSNEEHEAVCCG-FPGCSLKQEHMETLCCALSKCKAISQLDLTDNLLDDSGLRCLLGYLPQLPISGWLDLSHNSISQEGVLYLLETLPSYPHIQEVSVSLGTKQIFRMHFSKEEGTGTILRLCECSFSTEQVSRLTSNLS-HQQLTELWLTKCGLDPPQLTTLLNLVNRPAGLLDLRLEEPWVGYAGLPALMEVCAQASGCLTELSISESQEKLWLQLEFPRQEDHSEAMALRLAHCDLGTDHGLLMRQLVETCARLQQLSLSQVSFSDDDGTRSRLLQNILISSCELKSFRLTFSNVSTESPAHLASGLEHCHHLEELDFSNNSLCKEDTELLIGALQRTCRLKRLHLSHLPLETSSLDLLVQGLSNMTLLQDLCLKHSQIGDMG------------------------------------------------------------------------------------TQHLAAILPRLPGLRKLDLSGNRIGPAGGMQLVKSLTHFKNLEEIILGNNTLGDPTALELAQRFPPQLRVLCLTSSHLGPEGALCLAQALEQCPHIEEVSLAENNLAGGVPHFSKRLPLLKQINLVSCKIEDQAAKHLATNLTLCPALEKLLLSWNHLGDEMAAELAQVLPQMGQLKRVDLEKNQITACGAQLLAQGLVHGSCVPVIRLWNNPIPACVAQSLQSQEPRLDFSFFEQQPQTL---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q86WI3-1", "uniprot_id": "NLRC5_HUMAN", "id": "Q86WI3-1", "name": "Protein NLRC5", "aln": "MDPVGLQLGNKNLWSCLVRLLTKDPEWLNAKMKFFLPNTDLDSRNETLDPEQRVILQLNKLHVQGSDTWQSFIHCVCMQLEVPLDLEVLLLSTFGYDDGFTSQLGAEGKSQPESQLHHGLKRPHQSCGSSPRRKQCKKQQLELAKKYLQLLRTSAQQRYRSQIPGSGQPHAFHQVYVPPILRR--ATASLDTPEGAIMG-DVKVEDGADVSISDLFNTRVNKGPRVTVLLGKAGMGKTTLAHRLCQKWAEGHLNCFQALFLFEFRQLNLITRFLTPSELLFDLYLSPESD-HDTVFQYLEKNADQVLLIFDGLDEALQP--MGPDGPGPVLTLFSHLCNGTLLPGCRVMATSRPGKLPACLPAEAAMVHMLGFDGPRVEEYVNHFFSAQPSREGALVELQTNGRLRSLCAVPALCQVACLCLHH-LLPDHAPGQSVALLPNMTQLYMQMVLALSPPGHLPTSSLLDLGEVALRGLETGKVIFYAKDIAPPLIAFGATHSLLTSFCVCTGPGHQQTGYAFTHLSLQEFLAALHLMASPKVNKDTLTQYVTLHSRWVQRTKARLGLSDHLPTFLAGLASCTCRPFLSHLAQGNEDCVGAKQAAVVQVLKKLATRKLTGPKVVELCHCVDETQEPELASLTAQSLPYQLPFHNFPLTCTDLATLTNILEHREAPIHLDFDGCPLEPHCPEALVGCGQIENLSFKSRKCGDAFAEALSRSLPTMGRLQMLGLAGSKITARGISHLVKALPLCPQLKEVSFRDNQLSDQVVLNIVEVLPHLPRLRKLDLSSNSICVSTLLCLARVAVTCPTVRMLQAREADLIFLLSPPTETTAELQRAPDLQESDGQRKGAQSRSLTLRLQKCQLQVHDAEALIALLQEGPHLEEVDLSGNQLEDEGCRLMAEAASQLHIARKLDLSNNGLSVAGVHCVLRAVSACWTLAELHISLQHKTVIFMFAQEPEEQKGPQERAAFLDSLMLQMPSELPLSSRRMRLTHCGLQEKHLEQLCKALGGSCHLGHL-HLDFSGNALGDEGAARLAQLLPGLGALQSLNLSENGLSLDAVLGLVRCFSTLQWLFRLDISFESQHILLRGDKTSRDMWATGSLPDFPAAAKFLGFRQRCIPRSLCLSECPLEPPSLTRLCATLKDCPGPLELQLSCEFLSDQSLETLLDCLPQLPQLSLLQLSQTGLSPKSPFLLANTLSLCPRVKKVDLRSLHHATLHFRSNEEEEGVCCGRFTGCSLSQEHVESLCWLLSKCKDLSQVDLSANLLGDSGLRCLLECLPQVPISGLLDLSHNSISQESALYLLETLPSCPRVREASVNLGSEQSFRIHFSREDQAGKTLRLSECSFRPEHVSRLATGLSKSLQLTELTLTQCCLGQKQLAILLSLVGRPAGLFSLRVQEPWADRARVLSLLEVCAQASGSVTEISISETQQQLCVQLEFPRQEENPEAVALRLAHCDLGAHHSLLVGQLMETCARLQQLSLSQVNLCEDDDASSLLLQSLLLSLSELKTFRLTSSCVSTEGLAHLASGLGHCHHLEELDLSNNQFDEEGTKALMRALEGKWMLKRLDLSHLLLNSSTLALLTHRLSQMTCLQSLRLNRNSIGDVGCCHLSEALRAATSLEELDLSHNQIGDAG--------------------------------------------------------VQHLATILPGLPELRKIDLSGNSISSAGGVQLAESLVLCRRLEELMLGCNALGDPTALGLAQELPQHLRVLHLPFSHLGPGGALSLAQALDGSPHLEEISLAENNLAGGVLRFCMELPLLRQIDLVSCKIDNQTAKLLTSSFTSCPALEVILLSWNLLGDEAAAELAQVLPQMGRLKRVDLEKNQITALGAWLLAEGLAQGSSIQVIRLWNNPIPCDMAQHLKSQEPRLDFAFFDNQPQAPWGT", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**. . :*.*:***: **.**:*.****.**:: ***. * *. *. .* ***:*..** **:*** :*::*:***.:*: *:* :* * *:.**** :* * .:*:** ***.** *******:.:******.****:**:***** : . **: . *.*:**::: ::*.**: *** :* * :. *. **** ***. :.:*******:************:** :**.*:*: ***:**:******:**:: * .:******* ***: *:*:***::**.::***********:. :*.*..*..*****.**:* ***** **:********:*:*:*** *:* **** ***:**. *** *:* ** *:::* ***.:**:**** *:*:**: **.. :**** ****.:****:*** ::*.. * :*:*.:*:****** ****:* .:**.* *:::**.********: * .**:: ****.**.****:***:**** .*:**** :****:*:** ***.: *******:******* **: **.:*** :. **::**:*:***:***:*******::** * * ***: *** :.***** *.******* :***:*:******: ************************:******************.******* *: ***:**:***:*****:::****.**:***::****.* **.:*:::* * :*:***** **:. * **. .:.*:****** **.** :*** *** .**::: . *.* * .*. ::* ***.* ********:::**:**: *:*:.*:****:****:*:*:****:::*.******:*****:**** :** :*:*:*:* ** :***** :**:: **** .:*:*. : * * .:: :.***. ***:******: :* * **:** **: * ***:*.* * .:*. *::*** **.*:*****.*.:*:***:.** *:*:***:*:*::*:**: *:*** **** *.* :..:.* : ** .**:**.** **. .*: ** :*:..*****:****: *.*:**: **: ***:**** *:* :* **.:******: :.*** *:** **** **.*** ****.*.**** *.****.***:*:** ****: :**:**: ***.* ****** ***:**** ******.****. ********* *.::*.**.*.::* **: **::: :*. ***.**** .*:**:*::.** ***** **:* *. **: **.**.**:**:.**::***.. . : :*:********.:**:**** *.:* :*****:** :.:::********* :.*. *: **:** ***********.: ::*.: * ***.:*:* .***:**** * ***:. :*** ** *********:***.: :*.*: *: **: . **:*.**.* * :*:* ** : **.** **.* *.:..***:* .* **:*** ** ***:***** *..***:**.:**. ..***: ** *:**:**** ***.:* :**** *. ***** *** *****: .**:**:*********** :*. .****:**:* ***::*:*: *::.:* **** :*** * **** ************:**:*:** *:*** ** ***:**.:**.: ********* :** *:********:: ::*. ", "identical_positions": 1087, "similar_positions": 469, "identity": "56.32%" }, { "cls_id": "homologset.agr.RGD:1309167", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "G3V783-1", "uniprot_id": "G3V783_RAT", "id": "G3V783-1", "name": "Receptor-interacting serine/threonine-protein kinase 2", "aln": "MNGDAICSALPHIPYHKLADLHYLSRGASGTVSSARHADWRVRVAVKHLHIHTPLLDSERNDILREAEILHKARFSYILPILGICNEPEFLGIVTEYMPNGSLNELLHRKTEYPEIAWPLRFRILHEIALGVNYLHNMNPPLLHHDLKTQNILLDNEFHVKIADFGLSKWRMMSLSQSRSYKSAPEGGTIIYMPPENYEPGQKSRASVKHDIYSYAVIMWEVLSRKQPFEEVTNPLQIMYSVSQGHRPNTSEENLPFDIPHRGLMISLIQSGWAQNPDERPSFLKCLIELEPVLRTFEDITFLEAVIQLKKSKIQSASSTIHLCDKK-MDLSLNIPASHPPQEESCGSSLLSRNAGSPGTSRSLSAPQDKGFFHGGPQDCSSSKAYHCPGNHSWDGIISVSQEAAFCDRRASSCSLTVIRPLLVEKSSERPQPGIAQQWIQSKREAIVSQMTEACLNQSLDALLSRDLIMKEDYELISTKPTRTAKVRQLLDTSDIQGEEFARVIVQKLKDNKQMGLQPYPEVLLVSRTPSSNVLQNKTL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P58801-1", "uniprot_id": "RIPK2_MOUSE", "id": "P58801-1", "name": "Receptor-interacting serine/threonine-protein kinase 2", "aln": "MNGDAICSALPPIPYHKLADLHYLSRGASGTVSSARHADWRVRVAVKHLHIHTPLLDSERNDILREAEILHKARFSYILPILGICNEPEFLGIVTEYMPNGSLNELLHRKTEYPDIAWPLRFRILHEIALGVNYLHNMNPPLLHHDLKTQNILLDNEFHVKIADFGLSKWRMMSLSQSRSYKSAPEGGTIIYMPPENYEPGQKSRASVKHDIYSYAVIMWEVLSRKQPFEEVTNPLQIMYSVSQGHRPDTSEENLPFDIPHRGLMISLIQSGWAQNPDERPSFLKCLIELEPVLRTFEDITFLEAVIQLKKAKIQSSSSTIHLCDKK-MDLSLNIPANHPPQEESCGSSLLSRNTGSPGPSRSLSAPQDKGFLSGAPQDCSSLKAHHCPGNHSWDGIVSVPPGAAFCDRRASSCSLAVISPFLVEKGSERPPIGIAQQWIQSKREAIVSQMTEACLNQSLDALLSRDLIMKEDYELISTKPTRTSKVRQLLDTSDIQGEEFAKVVVQKLKDNKQLGLQPYPEVPVLSKAPPSNFPQNKSL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43353-1", "uniprot_id": "RIPK2_HUMAN", "id": "O43353-1", "name": "Receptor-interacting serine/threonine-protein kinase 2", "aln": "MNGEAICSALPTIPYHKLADLRYLSRGASGTVSSARHADWRVQVAVKHLHIHTPLLDSERKDVLREAEILHKARFSYILPILGICNEPEFLGIVTEYMPNGSLNELLHRKTEYPDVAWPLRFRILHEIALGVNYLHNMTPPLLHHDLKTQNILLDNEFHVKIADFGLSKWRMMSLSQSRSSKSAPEGGTIIYMPPENYEPGQKSRASIKHDIYSYAVITWEVLSRKQPFEDVTNPLQIMYSVSQGHRPVINEESLPYDIPHRARMISLIESGWAQNPDERPSFLKCLIELEPVLRTFEEITFLEAVIQLKKTKLQSVSSAIHLCDKKKMELSLNIPVNHGPQEESCGSSQLHENSGSPETSRSLPAPQDNDFLSRKAQDCYFMKLHHCPGNHSWDSTISGSQRAAFCDHKTTPCSSAIINPLSTAGNSERLQPGIAQQWIQSKREDIVNQMTEACLNQSLDALLSRDLIMKEDYELVSTKPTRTSKVRQLLDTTDIQGEEFAKVIVQKLKDNKQMGLQPYPEILVVSRSPSLNLLQNKSM", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:******* *********:********************:*****************:*:***************************************************::**********************.***************************************** **************************:********** ***********:***************** .**.**:*****. *****:****************************:************:*:** **:******* *:******..* ********* * .*:*** .****.****:.*: .*** * :*********. :* . *****::::.** ::* *: . .*** ************ **.***************************:*******:********:********:*:*********:*******: ::*::*. *. ***::", "identical_positions": 445, "similar_positions": 60, "identity": "82.41%" }, { "cls_id": "homologset.agr.RGD:1309168", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4A7S9-1", "uniprot_id": "D4A7S9_RAT", "id": "D4A7S9-1", "name": "RING-type E3 ubiquitin transferase", "aln": "----------------------------------------------------------------------------------------------------------------------------MSENRKPLPGFVNKLQDASASGS-----------------------------------------------------------------------------------------------------------------------------------------------------------SGKTHCPSCLRLFKVPRLLPCLHTVCTSCLE--------------------------------------------------------RLDPFSVVDIRGGDSDTSSEGSIFQEPKSCSLKPQIGILCPVCDAQVDLPLGGVKALTVDHLAMNDVMLESLHGEG---QGLVCDLCSDRE-VEKRCQTCKANLCHFCCQAHRRQKKTTDHTMVDLKDLKGYSRVGKP-----------ILCPSHPAEELRLFCELCDRPVCRDCVVGEHREHPYDFTSNVIHKHGDSVRELLR-DTQPHVEALEDALAQIKSSNNALQERVEAVAADVRTFSEGYIRAIEEHRDKLLRQLDDIRVQKENSLQLQKAQLEQLLADMRTGVEFTEHLLTSGSDLEILVTKGVVVERLRKLNKVEYSARP-----GVNHKICFSPQEKA-RCQG---YEVYGAINTQEVDPAQCVLQGEDLHRAREKQTASFTLVCKDATGESMSRGGDNVRVEVVPKNKKDSPIRTVVQDNKDGSYRVSYTPKEPGVYTVWVGIREQQVQGSPFNVTVRRKHRPHPGVFHCCTFCSSGGQKTARCACGGTMPGGYLGCGHGHKGHPGRPHWSCCGKFIEKSECSYS-TGQSAPRSLLRTVAL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PFY8-1", "uniprot_id": "TRI45_MOUSE", "id": "Q6PFY8-1", "name": "E3 ubiquitin-protein ligase TRIM45", "aln": "----------------------------------------------------------------------------------------------------------------------------MSEIRKPLLGFVHKLQDANASGS-----------------------------------------------------------------------------------------------------------------------------------------------------------SGKTHCPTCLRLFKVPRLLPCLHTVCTTCLE--------------------------------------------------------KLDPFSVVDIRGGDSDTSSEGSVFQDPELCSLQPQIGILCPVCDAQVDLPLGGVKALTVDHLAMNDVLLENLRGEG---QGLVCDLCSDRE-VEKRCQTCKANLCHFCCQAHRRQKKTTYHTMVDLKDLKGYSQVGKP-----------ILCPSHPAEELRLFCELCDRPVCRDCVVGEHREHPYDFTSNVIHKHGDSVRELLR-DTQPHVEALEDALAQIKSVNNALQERVEAVAADVRTFSEGYIKAIEEHRDKLLQQLDDIRIQRETALQLQKAQLEQLLADMRTGVEFTEHLLTSGSDLEILITKGVVVERLRKLNKVEYSARP-----GVNHKICFSPQEKAGQCQG---YEVYGAINTQEVDPAQCVLQGEDLHRAREKQTASFTLFCKDASGQSMGRGGDNVHVEVVPKDKKDSPIRTVVQDNKDGSYRVSYTPKEPGIYTVWVCIREQHVQGSPFNVTVRRKHRPHPGVFHCCTFCSSGGQKAARCACGGTMPGGYLGCGHGHKGHPGRPHWSCCGKFIEKSECSFT-SGQGAPRSLLRTVAL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H8W5-1", "uniprot_id": "TRI45_HUMAN", "id": "Q9H8W5-1", "name": "E3 ubiquitin-protein ligase TRIM45", "aln": "----------------------------------------------------------------------------------------------------------------------------MSENRKPLLGFVSKLTSGTALGN-----------------------------------------------------------------------------------------------------------------------------------------------------------SGKTHCPLCLGLFKAPRLLPCLHTVCTTCLE--------------------------------------------------------QLEPFSVVDIRGGDSDTSSEGSIFQELKPRSLQSQIGILCPVCDAQVDLPMGGVKALTIDHLAVNDVMLESLRGEG---QGLVCDLCNDRE-VEKRCQTCKANLCHFCCQAHRRQKKTTYHTMVDLKDLKGYSRIGKP-----------ILCPVHPAEELRLFCEFCDRPVCQDCVVGEHREHPCDFTSNVIHKHGDSVWELLK-GTQPHVEALEEALAQIHIINSALQKRVEAVAADVRTFSEGYIKAIEEHRDKLLKQLEDIRAQKENSLQLQKAQLEQLLADMRTGVEFTEHLLTSGSDLEILITKRVVVERLRKLNKVQYSTRP-----GVNDKIRFCPQEKAGQCRG---YEIYGTINTKEVDPAKCVLQGEDLHRAREKQTASFTLLCKDAAGEIMGRGGDNVQVAVVPKDKKDSPVRTMVQDNKDGTYYISYTPKEPGVYTVWVCIKEQHVQGSPFTVMVRRKHRPHSGVFHCCTFCSSGGQKTARCACGGTMPGGYLGCGHGHKGHPGHPHWSCCGKFNEKSECTWT-GGQSAPRSLLRTVAL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7T6Z0-1", "uniprot_id": "A0A8N7T6Z0_DANRE", "id": "A0A8N7T6Z0-1", "name": "RING-type E3 ubiquitin transferase", "aln": "----------------------------------------------------------------------------------------------------------------------------MSLCKE--KGDIAQSKSNGDSLK-----------------------------------------------------------------------------------------------------------------------------------------------------------KSRAVCGVCNRMYREPKILPCLHTFCADCVR--------------------------------------------------------QLEPFSVRRVNG---DRRSPG----EDNSGSGS---TILCPQCDSEVDLPPSGVDGLTTDHLALDEVFTETLVVN----NSVLCDLCSDSD-AGKRCEVCCVNLCDFCSQAHRRQKRTSSHSIQTLQELKSQGRLTRP-----------ILCSLHPGQELRLFCEPCDLTVCLECAATFHREHHCSSTHEVISRYGDRIRDLLVRSLKPRLARLEESLRRVDTSQEAMQARTDTLAGEIRAFARAYASAVEAHCCSLLRSLDDLRTQRRNQLQLQKAQLQQALSDVRGGVEFTERLLMCGSDAEILTAKGVTMRRLVNLVESGFDPQPSTVASDNASSICFLPQESAGEVEG---FPVVGAIHAKTVDPSKCTIQGEGVERGCEGQRGEFTLVCRDTSGEQMGQGGDPVMVSIVHREKKGCSVEASVVDNSDGSYCVSYSPAEAGLYSVWVCVKAQHVQGSPFVLNVKRKLRRHSGIFHCCSFCSSGGSKEARCGCTGTMPGGFKGCGHGHKGHPGKPHWSCCGSVMEASECVLHNLGSMSPRGHLRTVEL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VLR7-1", "uniprot_id": "Q9VLR7_DROME", "id": "Q9VLR7-1", "name": "Tripartite motif-containing protein 45", "aln": "MSRENRSKIAFKRKTSNGNKSGQLTDYERIRGDVEIVVPSPPPTPAVPPSASLGKLKIKLSSAKISLRKNAQTSQNNLQTAPLPDAVRRKSAPQLFTFTIAPKSEVTSKIHLPSVPKLPGLAPKSSIRRSRTLGLSNSAQGAGSSGTGLSNVELGVQDRDSGSEPTSSLAGGGSSTSPESLLDNILSGASSVSVQSSSSSQASNATVAQPIKAKEQLHPKRLLSLKASPELRVSPPTPDTTQPQVQMPTQLLLSLTPRPEVFDAPSPLTRSPSRSPGISPPVSPSPSITLRPSTPPENTVIFTDDLKCGICLDVYTDPRTLHCLHSFCLQCLVSENFKDESLWDQDQARSEEPSNYSLRSEMGGSSAELTATVSPARQRGSSFTLRRKKSMDRLVIRSKSDGKRSTSSIGTRFTGSFASEVSTR-CIRCHTCNYPTDLSLGGVRQLPQNYLLVRRIEVLRLQAGEDVISRVWCSLCTEEISATYHCISCTLNLCTLCKEAHERQRSTASHRMRSILELRRARKQKQQQMGLGDSSKLVLRCGIHTNFELKAFCTNCRQLACTDCLVILHKGHRHETISRAIGHQGKLLKEATD-QTRPLCQYAEHSIERLNAIARGINDRCDDIQTQVERYMQQYMDALTVHRKTLLQQISRARESKVEVVLKQQLDLEKRTQQAMDAVRFSQELCEIGADVEILSYVTILLRRLEYCQQFKPPVDP-----KISDSLHFLPKIRAPSTKDQRDIPLYGIITMQVVEPSLCTLEWEGFSQLRLHKKADLLLHSRDADGVSLCHGGLEINCMLKYKDSSSKFLPVEVSDNRDGTYNISFTPDAQGTLILTITINDRPIKGGPFTFQAR-QVRPHTGIYHCCSFCSGKGNRNVMCSCEGHMPG-YSGCGHGHAGHPGRRHWSCCGNVLENSECNVANKLLNS----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :. * . . . .. * * :: *: * ***:.* *: :: : : . . * * . . * * *: .**. .** *. ::* : : * . : *.**.: . :* * *** :* :**.**: *: * : : :*: : : : * *. **: ** * .* :* . *: * . ..* : *. : : :* *.:: ::. .:: * : : ::. : . * *: * .**:.:. * .: : *: :*:: : .*.*::.* *:* *** : :.** : * .: * *: * .. : * * : *:*: *.:: *.. : : ..: * .:*: * : :** : : ::... : . * ** **:* :*::* * : : :. : ::*.** . .: : * *.*::***:***. *.: . *.* * *** : ****** ****: ******.. * *** : ", "identical_positions": 136, "similar_positions": 166, "identity": "14.47%" }, { "cls_id": "homologset.agr.RGD:1309170", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K1J3-1", "uniprot_id": "A0A0G2K1J3_RAT", "id": "A0A0G2K1J3-1", "name": "", "aln": "----------------------------MTER--------NKGCFIVRHTPHPRRVCHIQGLNNVPICTVKDD-LPIRMLCCPRQLSPSQKNETTLAKVSNPPRSASPESLSIRGVSPAKN--KVPERPHSEPFRKINHNFRTSRDNPLVNKKDEYKPKKPLVASRMCSGAASPSSDVMNTRINRNENTVCIPNYLDQEIKILLKLCDILHTDSLTEVLDWLLQASNKEKEWLSALIHSELSEINLLTRHRVNTP-EPAAESRKSPTSVTP-TTKLLQNSHAKLKALHESREEHQPLRMTSQGSEGNKMASKGAET--PLFIRRNKK-LPVTEYFNNPKSPFKPNTQESRSARPMSVRSVQGY--SPQRALYPLTHGREK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A5F8MPV9-1", "uniprot_id": "A0A5F8MPV9_MOUSE", "id": "A0A5F8MPV9-1", "name": "", "aln": "-----------------------------MES--------VGGCFIVRHTPHPRRVCHIQGLNNIPICTVNDDDTCPRSLYISDQFSPSERNETSVAKFTNPPSTASPESLRVGGLSPAPA--KLPARPQSEPCRKSSQCFKTSKDNPLVKNKVEHKAKRPLPSARMCSAAAFQSSDAMSNRMDGNENTVHIPNYLDQEIKILAKLSEILHTDSLAEVLNWLLQASNKEKEWVSALVHSELAEINLLTRHRANTPTEPAAEPRKPYTSGTP-TTKLLQNSRAKLKALTGSRE-RQLHRTSSQGSKGNKLVSHGAET--PLFIRRNKKQTPVTEYLN-PESPLGSNSVASRSPNPGSARSAQGY--SPQRVFYP-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q53FE4-1", "uniprot_id": "CD017_HUMAN", "id": "Q53FE4-1", "name": "Uncharacterized protein C4orf17", "aln": "----------MNLNPPTSALQIEGKGSHIMAR--------NVSCFLVRHTPHPRRVCHIKGLNNIPICTVNDDENAFGTLWGVGQSNYLEKNRIPFANCSYPSSTAVQESP-VRGMSPAPNGAKVPPRPHSEPSRKIKECFKTSSENPLVIKKEEIKAKRPPSPPKACSTPGSCSSGMTSTKNDVKANTICIPNYLDQEIKILAKLCSILHTDSLAEVLQWLLHATSKEKEWVSALIHSELAEINLLTHHRRNTSMEPAAETGKPPTVKSPPTVKLPPNFTAKSKVLTRDTEGDQPTRVSSQGSEENKEVPKEAEHKPPLLIRRNNMKIPVAEYFSKPNSPPRPNTQESGSAKPVSARSIQEYNLCPQRACYPSTHRR--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6Z3N1-1", "uniprot_id": "A0A8M6Z3N1_DANRE", "id": "A0A8M6Z3N1-1", "name": "", "aln": "MDESEQQANVSVSRADLSSVQRESAGSRATTRGSLRFGTLSHHSFFSRHNPHPHRVRHMQGLNGKPVCMVNDDWFAFTPLCPHPLIKSQVSVSGSRSSAFFTPEISSDRSGPRAALISESWREELKDLATKITLSAAAETQHDKREPQKHADDEAPRRKTQYSSQSGRIIPSSSWGGKKRSRTSHRRMTTHTHMLEGLELKVLELLCQILQTDSLSMVQQWLLLASDKEKELVQGLLKQAVSDCSSLSLHTSADPLNTEHLLLEPAG---------------------------RAHRSSLRRSE------------------------------TLPEEPERIGEAEVLTLYPENT-----------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .*: **.***:** *::***. *:* *:** * . . :. .. : .* .: . :: . . . . : . : .. : * . .. .. .: . . * . *:*:* *..**:****: * :*** *:.**** :..*::. ::: . *: * . :. :. : * : : *: . *:.* . : * .. ", "identical_positions": 48, "similar_positions": 78, "identity": "12.63%" }, { "cls_id": "homologset.agr.RGD:1309172", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZL10-1", "uniprot_id": "D3ZL10_RAT", "id": "D3ZL10-1", "name": "", "aln": "-----MLLILFLMMICLHVCANQDSGPE----YADVVFLVDSSDHLGMKSFPLVKTFIQKLVSSLPVEANKYRVALAQYSDALHNEFHLGAFKNRNPMLNHLKKNFGFIGGSLKIGNALQEAHRTYFSAPTNGRDKKQFPPILVVLASAESEDDVEEASKALREDGVKIISVGVQKASEEDLKAMATS-------------------------------------------------------------------------------------------------------------------------------------------------QFHFNLRTARDLS-----------------------------------MFAPNMTQIIKDVTQYREAMTDDIIVEACQGPSVADVVFLLDMAINGSQENLDHLKAFLGESVSALDIKENCMRVGLVAYSNETRVISSLSMGVNKTEVLQRIQDLSPHVGQAYTGAALRKTRKEVFSAQRGSRKNQGVPQIAVLVTHRASDDNVTKAAVNLRREGVTVFTMGVEGANPEQLEKIASYPAEQFTSKLSNFSELATHNQTFLKKLRNQITHTVSVFSERTETLKSACVDTEEADIYLLIDGSGNTQPTDFHEMKIFLSEVVDMFNIAPHKVRVGAVQYADTWDLEFEISKYTNKPDLGKAIDNIRQMGGNTNTGAALNFTLTLLQRAKKQRGNKVPCHLVVLTNGMSQDSVLGPAHKLREENIRVHAIGVKEANQTQLREIAGDEKRVYYVHEFDALRDIRNQVVQEICAEEACRDMKADIMFLVDSSGSIGLENFSKMKVFMKNLVSKSQIGADRVQIGVVQFSHENREEFQLNTFMSQNDIANAIDQMAHIGETTLTGSALTFVSQYFSPEKGARPNVRKFLILITDGEAQDIVKDPAVALRKDGVIIYSVGVFGSNVTQLEEISGKPEMVFYVENFDILQHIEDDLVLGICSPREE-CKRIEVLDVVFVIDSSGSIDYQEYNIMKDFMIGLVKKADVGKNQVRFGALKYADDPEVLFYLDELGTKLEVISVLQNDQPMGGNTYTAEALAFSDHMFTEARGSRLHKGVPQVLIVITDGESHDAEKLNATAKALRDKGILVLAVGIAGANTWELLAMAGSSDKYYFVETFGGLKGIFSDVSASVCNSSKVDCEIEKVDLVFLMDGSNSIHPDDFQKMKEFLASVVQDFDVSLNRVRIGVAQFSDSYRSEFLLGTFTGEKEISTQIEAIQQIFGYTHIGDALRKVKHYFRPDTGSRINAGTPQVLLVLTDGRSQDEVAQAAEELRHKGVDIYSVGIGDVDDQQLIQITGTAEKKLTVHNFDELKKVKKRIVRNICTSG--GESNCFVDVVVGFDIS-SQRRGQTLLEGQPWMGTYLQDLLRAISSLNGVSCEVGTETQVSIAFQVTNAMERYPS--KFEIYSENILSSLQGVTVNGPSRLNPNLLSSLWDTFQNKSAARGKVVLLFSDGLDDGVEKLEQKSDELRKEGLNALITIAVDGAADSSDLADLLYIEFGKGFEYRTQFTIGMGNLGSHLSKQLINVAERTCCCLLCKCTGWDGAMGDPGSAGEKGPPGFKGSEGYLGEEGIAGERGALGPMGEQGTKGCLGAKGPKGARGLSGEEGEVGEDGLDGLNGEQGDSGIPGRRGERGDAGSQGSPGKRGASGDRGPKGLRGDPGTPGRDNSIQGPKGLKGDPGRQGRRGWPGSPGTPGSRRKMVVHGRRGHTGPQGNPGITGPDGLEGSPGLKGPQGPRGEVGEKGEKGGFGMKGPQGPPGPKGRAGNQGHWGSQGSKGEPGDLGEKGAAGFPGPRGLQGDDGSPGYGSIGRKGTKGQEGFPGESGPKGDIGDPGDPGEAGPKGARGKTVSAGIPGEPGSPGEPGPPGRKGMKGARGLASFSTCDLIQYVREHSPVRHG------KPECPVHPTELVFVLDQSRDVTEQDFERMKGMMASLVRDIKVRDASCPVGARVAILAYNSHTRHLIRFSDAYRKDQLLREIKALPYEKSSDSREIGKAMRFISRNVFKRTLPGAHVRRIATFFSSGQSADVQSITTAAMEFSALDIIPVVIAFSNVPSVKRAFSIDDTGTFQVLVVPSRPDQVPALERLQRCTFCYDLCKPDASCDQAKPP-IQSYLDAAFLL--DSSWHVGGAEFEDMRDLLEALLDHFEIASEPETSVTGDRVALLSHAPVDFLPNTQRSPVRTEFNLTTYSSKHLMKRHVEQAVQQLNGDAFLGHALRWALDNVFLNTPNLRRNKVIFVISAGETSHLDAETLKKESLRAKCHGYALFVFSLGPDWDDKELEDLASHPLDQHLIQLGRIHKPDHGYGVKFVKSFINSIRHGINKYPPVNFKAKCS--------RLSSAAPKLSPRQFRSFVPGPQKALLKDHTLEAAKLFQDKKRLSS-----ILRSGR-AALSSHSRSTR---------------------------------YSFKQGREATKATSKLGKRSD-----------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C6K9-1", "uniprot_id": "CO6A6_MOUSE", "id": "Q8C6K9-1", "name": "Collagen alpha-6(VI) chain", "aln": "-----MLLVLCLTMICFHVCVNQDSGPE----YADVVFLVDSSDHLGLKSFPLVKTFIHKMISSLPIEANKYRVALAQYSDALHNEFQLGTFKNRNPMLNHLKKNFGFIGGSLKIGNALQEAHRTYFSAPTNGRDKKQFPPILVVLASAESEDDVEEAAKALREDGVKIISVGVQKASEENLKAMATS-------------------------------------------------------------------------------------------------------------------------------------------------QFHFNLRTARDLS-----------------------------------VFAPNMTEIIKDVTQYREGMADDIIVEACQGPSVADVVFLLDMAINGSQEDLDHLKAFLGESISALDIKENCMRVGLVTYSNETRVISSLSTGNNKTEVLQRIQDLSPQVGQAYTGAALRKTRKEIFSAQRGSRKNQGVPQIAVLVTHRASEDNVTKAAVNLRREGVTIFTMGIEGANPDELEKIASHPAEQFTSKLGNFSELATHNQTFLKKLRNQITHTVSVFSERTETLKSACVDTEEADIYLLIDGSGSTQPTDFHEMKTFLSEVVGMFNIAPHKVRVGAVQYADTWDLEFEISKYSNKPDLGKAIENIRQMGGNTNTGAALNFTLKLLQRAKKERGSKVPCHLVVLTNGMSRDSVLGPAHKLREENIRVHAIGVKEANQTQLREIAGEEKRVYYVHEFDALRNIRNQVVQEICAEEACRDMKADIMFLVDSSGSIGPENFSKMKMFMKNLVSKSQIGADRVQIGVVQFSHENKEEFQLNTFMSQSDIANAIDRMTHIGETTLTGSALTFVSQYFSPDKGARPNVRKFLILITDGEAQDIVRDPAIALRKEGVIIYSVGVFGSNVTQLEEISGKPEMVFYVENFDILQHIEDDLVLGICSPREE-CKRIEVLDVVFVIDSSGSIDYQEYNIMKDFMIGLVKKADVGKNQVRFGALKYADDPEVLFYLDELGTKLEVVSVLQNDHPMGGNTYTAEALAFSDHMFTEARGSRLHKGVPQVLIVITDGESHDAEKLNTTAKALRDKGILVLAVGIAGANSWELLAMAGSSDKYYFVETFGGLKGIFSDVSASVCNSSKVDCEIEKVDLVFLMDGSNSIHPDDFQKMKGFLVSVVQDFDVSLNRVRIGVAQFSDSYRSEFLLGTFTGEREISTQIEGIQQIFGYTHIGDALRKVKYYFQPDMGSRINAGTPQVLLVLTDGRSQDEVAQAAEELRHKGVDIYSVGIGDVDDQELVQITGTAEKKLTVHNFDELKKVKKRIVRNICTSG--GESNCFVDVVVGFDIS-SLQRGQTLLEGQPWMGSYLQDLLRAISSLNGVSCEVGTETQVSIAFQVTNAMERYPS--KFEIYSENILSSLQGVTVNGPSRLNANLLSSLWDTFQNKSAARGKVVLLFSDGLDDGIEKLEQKSDELRKEGLNALITIAVDGAADSSDLADLLYIEFGKGFEYRTQFTIGMRNLGSQLSRQLINVAERTCCCLLCKCTGGDGAMGDPGSAGKKGPPGFKGSDGYLGEEGIAGERGASGPMGEQGTKGCFGAKGPKGTRGLSGEEGEVGEDGLDGLDGEQGDHGIPGRRGEKGDEGSQGNPGRRGAAGDRGAKGLRGDPGTPGRDSSIQGPKGLKGDLGRQGRRGWPGSPGTPGSRRKMVVHGRRGHIGPQGNPGTPGPDGLAGSPGLRGPQGPRGEVGEKGEKGSLGMKGPQGPPGPGGQAGSQGHLGSQGNKGEPGDLGEKGAAGFPGPRGLQGDDGSPGYGSIGRKGTKGQEGFPGESGLKGDIGDPGDPGEAGPKGARGKTVSAGIPGEPGSPGEPGPPGRKGVKGARGLASFSTCDLIQYVRDHSPGRHG------KPECPVHPTELVFVLDQSRDVTEQDFERMKGMMVSLVRDVKVREANCPVGARVAILAYNSHTRHLIRFSDAYRKDQLLTAIKALPYERSSDSREIGKAMRFISRNVFKRTLPGAHVRRIATFFSSGPSADAQTITTAAMEFSALDIVPVVIAFSNVPSVKRAFSIDDTGTFQVIVVPSGSDEGPALERLQRCTFCYDLCKPDASCDQAKPPPIQSYLDTAFLL--DGSRHVGSAEFEDMRDFLEALLDHFEITSEPETSVTGDRVALLSHAPLDFLPNTQRSPVRTEFNLTSYSSKRLMKRHVDQAVQQLHGDAFLGHALGWALDNVFLNTPNLRRNKVIFVISAGETSHLDAETLKKESLRAKCHGYALFVFSLGPDWDDKELEDLASHPVDQHLIQLGRIHKPDHGYSVKFVKSFINSIRHGINKYPPVNLKAKCN--------RLGSRDLKPPPRQFRSFVPGPQKANLKDHTAEAAKLFQDKKRLSS-----MLKGGR-ATISSLSRSTR---------------------------------YAFKQGKEAIKATSKLGKRSA-----------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NMZ7-1", "uniprot_id": "CO6A6_HUMAN", "id": "A6NMZ7-1", "name": "Collagen alpha-6(VI) chain", "aln": "----MMLLILFLVIICSHISVNQDSGPE----YADVVFLVDSSDRLGSKSFPFVKMFITKMISSLPIEADKYRVALAQYSDKLHSEFHLSTFKGRSPMLNHLRKNFGFIGGSLQIGKALQEAHRTYFSAPANGRDKKQFPPILVVLASSESEDNVEEASKALRKDGVKIISVGVQKASEENLKAMATS-------------------------------------------------------------------------------------------------------------------------------------------------QFHFNLRTVRDLS-----------------------------------MFSQNMTHIIKDVIKYKEGAVDDIFVEACQGPSMADVVFLLDMSINGSEENFDYLKGFLEESVSALDIKENCMRVGLVAYSNETKVINSLSMGINKSEVLQHIQNLSPRTGKAYTGAAIKKLRKEVFSARNGSRKNQGVPQIAVLVTHRDSEDNVTKAAVNLRREGVTIFTLGIEGASDTQLEKIASHPAEQYVSKLKTFADLAAHNQTFLKKLRNQITHTVSVFSERTETLKSGCVDTEEADIYLLIDGSGSTQATDFHEMKTFLSEVVGMFNIAPHKVRVGAVQYADSWDLEFEINKYSNKQDLGKAIENIRQMGGNTNTGAALNFTLSLLQKAKKQRGNKVPCHLVVLTNGMSKDSILEPANRLREEHIRVYAIGIKEANQTQLREIAGEEKRVYYVHDFDALKDIRNQVVQEICTEEACKEMKADIMFLVDSSGSIGPENFSKMKTFMKNLVSKSQIGPDRVQIGVVQFSDINKEEFQLNRFMSQSDISNAIDQMAHIGQTTLTGSALSFVSQYFSPTKGARPNIRKFLILITDGEAQDIVKEPAVVLRQEGVIIYSVGVFGSNVTQLEEISGRPEMVFYVENFDILQRIEDDLVFGICSPREE-CKRIEVLDVVFVIDSSGSIDYDEYNIMKDFMIGLVKKADVGKNQVRFGALKYADDPEVLFYLDDFGTKLEVISVLQNDQAMGGSTYTAEALGFSDHMFTEARGSRLNKGVPQVLIVITDGESHDADKLNATAKALRDKGILVLAVGIDGANPVELLAMAGSSDKYFFVETFGGLKGIFSDVTASVCNSSKVDCEIDKVDLVFLMDGSTSIQPNDFKKMKEFLASVVQDFDVSLNRVRIGAAQFSDTYHPEFPLGTFIGEKEISFQIENIKQIFGNTHIGAALREVEHYFRPDMGSRINTGTPQVLLVLTDGQSQDEVAQAAEALRHRGIDIYSVGIGDVDDQQLIQITGTAEKKLTVHNFDELKKVNKRIVRNICTTA--GESNCFVDVVVGFDVS-TQEKGQTLLEGQPWMETYLQDILRAISSLNGVSCEVGTETQVSVAFQVTNAMEKYSP--KFEIYSENILNSLKDITVKGPSLLNANLLDSLWDTFQNKSAARGKVVLLFSDGLDDDVEKLEQKSDELRKEGLNALITVALDGPADSSDLADLPYIEFGKGFEYRTQLSIGMRELGSRLSKQLVNVAERTCCCLFCKCIGGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPGYGSVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKGLASFSTCELIQYVRDRSPGRHG------KPECPVHPTELVFALDHSRDVTEQEFERMKEMMAFLVRDIKVRENSCPVGAHIAILSYNSHARHLVRFSDAYKKSQLLREIETIPYERSSASREIGRAMRFISRNVFKRTLPGAHTRKIATFFSSGQSADAHSITTAAMEFGALEIIPVVITFSNVPSVRRAFAIDDTGTFQVIVVPSGADYIPALERLQRCTFCYDVCKPDASCDQARPPPVQSYMDAAFLL--DASRNMGSAEFEDIRAFLGALLDHFEITPEPETSVTGDRVALLSHAPPDFLPNTQKSPVRAEFNLTTYRSKRLMKRHVHESVKQLNGDAFIGHALQWTLDNVFLSTPNLRRNKVIFVISAGETSHLDGEILKKESLRAKCQGYALFVFSLGPIWDDKELEDLASHPLDHHLVQLGRIHKPDHSYGVKFVKSFINSIRRAINKYPPINLKIKCN--------RLNSIDPKQPPRPFRSFVPGPLKATLKEDVLQKAKFFQDKKYLSR-----VARSGRDDAIQNFMRSTS---------------------------------HTFKNGRMIESAPKQHD---------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TBZ3-1", "uniprot_id": "A0AB32TBZ3_DANRE", "id": "A0AB32TBZ3-1", "name": "", "aln": "MGKAQTFLFVFLFASCFLVSTAQLTGCQDENPPYDIVFLVDSSSSIGTRDFREVKTFMHTFVDGLEIDTKKVQVGVVQFSTDPHKEFLLGEYANKAELFRKIDN-LPYRTGGTYMGKAMNFLKDNYFTSAGGSRVSEKVPQVVVVITDGDSTDDIKGPAEDLRKKGIIIFAIGVGSTNMTELKAIASTPPERFVVNIDNYQALQGLTTTMKETVCVLMRDQGKALAPKFTDVFVLVDSTAQGETQQIRELLNRLLVQLNVGDGSNKIALAQFGENVVKEFLFKDYQTAQKAREFINRFEPRLNGERKLGKAIDYVRTNFLNTVSGSRIAKGYKQYLLVLRTGDSYDSTVRAIRTMKNEDVSVIDIRLEPNLQSLFPSLRAFQIDQNVIDVAADVTKRIQEKEVFNVTGDCRSAQVADIVFIVDESGSITRNNFELIKRFLHRIISGLEVNSDSVRVGMVLYNDRPSAEFYLDTFANKNDIMNYIKIIPYRGGGTATGAALKFAQNNLFTQKRGSRKALGVKQIAIVMTDGESEDDVTTTAAELRRSGVTVYALGVKNASVEELKKIGSYPEHEFVFNVGSFLMLSSLEKSLRKSLCKVVVNRRFDKNNR-LLLKQGCVNTEEADIYFLLDNSGSTR-ADFEDVKKFILGSLQLFNIGPNRVRVGVVKVDRNPTLQFSLTEHKNRASFEAAVRGISQPVGGSEKGKALKYVASLFNQAKASRPAKVQEILIVITDKTSQDDVGDPAEELRIQGVSVYAIGVKDASQDELLKMTADETKDFYVTNYDALNVLKREIVTDICSQEACKNKVADIMFLIDGSSSIYGPDFTSMKTFITKVVNGTIIGEDSVHVGVVQFSNNPQEQFPLNRYFDQNELEEAIDGIEQLTGDTYTGKALSFISKYFDASNGGRPDVPQFLVVITDGEAHDAVAVPAKAIRDKGVTIFSIGVASVNTTQLWEISGTQDKVYVQRDFDALHSIDKNLQFKLCSSHPGGCPSTQLADVIFLVQCTRQIRLQDFEKIKSFLISVVNSTQIGDNLIRFGVIVYSDTP-SQFSLNQYNTRRQIAEAITSLKSPAVSGYTARALAYSLTYFTEANGGRQKRGVPQMLFMITDGDARDRENLRARADEFAAKQINVYGIGVARAQDSELEIITKSKNKIFHVNNYDNLQDLQMNVSGVLCNATKPVCQNEVADLVFLIDGSESISEESWITVIAFLLNVVDKLRIGPELFRVGIAQFSSVYQKEFYMNEYKDADGVKSAIRRITQIKEGTLIGKALSNVVEFFQEDKGSRKQSGVPQNLVLITDGVSSDRVNEAADQLRNLGINVFAIGIGAVSLQQLSYIAGSPDRLFKVQNFNYLNLTTATFVDALCVPLPLAQASCTIDIGIGFDNSRTSSSSRSIFRDQMKLQTYLPEIIRSISEVHNLCCITKPTIKTNIGFRLVDATGKRLDDFSFEEYDVGVLNKVMALQTSQSLKFNNLLLRSFEEKFR-ASNSFVKVLIIFTDGLDEPVENLLSTVNSLRTNGVKALLTVALDGYKSTT---DLQRLEFGRGLRYKQLLSIGMQSVASVMQKEIDNIASRECCNVACKCSGHEGSRGFQGLPGSKGLPGRRGNSGYPGEEGGHGERGLPGLNGTRGNQGCPGRRGLKGGRGYRGENGEEGDNGLDGVDGEQGKTGAPGSPGERGDPGNPGPTGISGSSGSPGQRGLRGDPGNSGLDNNARGRKGDAGSAGMQGDPGPDGLAGQSGENGRPGQSGRRGTAGLPGPRGPPGDPGLQGLPGGSGPQGPFGPPGPVGQRGFVGLPGPQGSPGSPGRPGTKGSLGSRGQKGQPGDPGEKGSLGSAGSRGLPGKDGNDGYGYPGLKGQKGDSGFPGYPGLQGELGFKGTNGGVGPKGSRGRGGNAGRTGPPGDPGSGGMTGHRGPKGPRGARQMSDCQLISYVRDNCMCCKGRCVLLDNIKCPAYPTDLVIGMDMSEDVTPQGFERMRSVVLRLLDNMKIAESSCPTGARVALVSYSSFTKYLIRFNDYHRKKQLIDAVNNIALERTSNRRNIGAAMRFVGRNVLKRVRKGILMRKVAIFLTAGESQDSISLTTAILEYKALNIKLGVIALRNVPAIRRAFEADESQSFILTVLGRVQDQNATLSKIQSCVICYDPCRPARECEGTNLPSAPQELDMDFVMVVDGSRSILADEFKGVKEVLGGVLDQIVVSSQPTRADRQARVALYQQTSTYSDP----QPAHEIFSLREFSDRNLMKTSIIQKLKQTGGSHELGSTLEFAFKKCFNAVPESRKNKMLLAIIGEETALQEKKRLDSFSRLAKCSGIVLFTLTVGDSIASSQVEELASYPLEQHIIHLGHLKHGEQEYTQRFMRTFFHILSKNMNTYPHPSLQSQCRNFQESPGQRLDFEAAERPVYRVPVLSTVYPDVQVEEDMEEEDTAPETEDQQSSGRGDSIIQSPADNTDSLCRQSSDRGTVCGDYMQRWYYNPAVRGCLPFWYGGCGGNGNRFSSERECLQTCGKKNPEVIPQTQVETALFNDACLMKQDVGPCSNYVLSWYYDIQQNECSQFWFGGCEGNKNRFETRAECEALCLKDIQPV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*.: * * :.. * :* : *:*******. :* :.* ** *: .::..* :::.* :*.:.*:* *.** *. : .: ::.:: : : : *. :*:*:: : .**::. ..* .::.* ::**::..:* *::: .:: **:.*: *:::** .:. :***:*:: *: : *** . . : *: .: ** : : .. *:...:**:**::* : . :.:::: :* ** . :*.*:::.:.:***:* *.:.. . *. **.:::: *: :. : * : ****:: ::::*: :.**** ** ***:::*. *:*:**.:*.:***.***::::*::.*. :*:**.*:* .::. :: .* *:: :::: *.* : :.: .:* **..**:*******:*:*.**.*: :**.::* *: : :***.*::****.*: . *:*.:.::.*: .: *: .* * *.::.* **::. .*:::** .* ** *:*:*: *:*.: **..** : : *:***:*:*.* :* :::.:*.: :** ::***. ::.::* :**::***:: ******:*.*.** :*:.** *:.::*. : ** * *::******. :*:* ** ::.*.:: :*** : :: * **.**:*:*:**.. :*.**:: :**::******:* * ** .:*..** *:*:** . *.*** **** : *: .:** *: *:.:* : :**.: * :: **:*:::.: .* :::: :*.*:*.:*:.:::*.* :***.: *:* * * *:: .*: :: ..: . :. . . ***.**.:* ****.*.* ::****:*::****:::* ::*.: *. : * * * .:*: *: ** :: *.:* :.*:.:..*:.: :*:. :**::* *: : .*****:*** ** :.: .: ** .**:.: :. : .*:* ****. *: ** :. : . :. *. * ** * ** ** :* :*: * *** ::*.** *:::*** *.*.* :**: **: *::::::*** *. *:* *:*:.:: :.*:**: *: .. :* :*.. .::.* :*: :*** * : .::::..* : :** :::*:**.::.:.* . . :..:.*::.:* : .** *. .:*..: : .. . :* ** *: :.*: * : **:::*:****: :*:* .. :.**.:*::**:*:*:** .:: ** :***:*:.*: ::*** .:.* :.::: *:*.* ** : *** * :*: * * .*.:* ** :*..** **** **** * * :*.:** * :* ** ** *::** *::*:**::****. * ** **:** *. * .* *:.*. * :******* .* *.. .* .* *. * ** * * .* .*.. : **** * * * .* ** * * ***** * * *::* .* ****.**. *..*.:* **:*.**:*** ****: * .*.*** *.**. *** * ** **:.**** .* :*::* * * .* **:**: .** .* *.**. * .*::* **.:* .:* *:**.***:.. :* : :**.:**:**: :* *.*** * ****: :: *: ::*: : .**.**::*:::*.*.:::*:**.* ::*.**: :: :. *::* *:** ****:.***:**. * *::* *:::* * * ::*** :*: **:* **:: ***:::*** *:: :* : *: * .:*.::* *.:*** *:* .*: :. * . :* *:: *.* : . **:.:: .* .:**:: ::.:* : **** .::. * .*.: *.* : .:.*** : : ::* *. :* :* :::.: * .*: *:**:::.* . **: : : *.. * *** * .**.:::* ..::*:***:*:::*:::**:::: :: * :*:::*:: : : :*.** .:: :* **. : . . : . .. :::. : . : :. * : :. : . :*: *.. : .: : . ", "identical_positions": 767, "similar_positions": 863, "identity": "29.66%" }, { "cls_id": "homologset.agr.RGD:1309174", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZG87-1", "uniprot_id": "D3ZG87_RAT", "id": "D3ZG87-1", "name": "RPE-retinal G protein-coupled receptor", "aln": "MTATRALPAGFGELEVLAIGIVLLMEALSGISLNGLTIFSFCKTPDLRTPSNLLVLSLALADTGISLNALVAAVSSLLRRWPHGSEGCRVHGFQGFATALASICGSAAIAWGRYHHYCTRRQLAWDTAIPLVLFVWLSSAFWASLPLMGWGHYDYEPVGTCCTLDYSRGDRNFISFLFTMAFFNFLVPLFITHTSYRFMEQKLSRSGHLQVNTTLPGRMLLLGWGPYALLYLYAAVADVSFISPKLQMVPALIAKTMPTINAINYALRSEMVCRGTWQCRSAQKSKQDRTQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z2B3-1", "uniprot_id": "RGR_MOUSE", "id": "Q9Z2B3-1", "name": "RPE-retinal G protein-coupled receptor", "aln": "MAATRALPAGLGELEVLAVGTVLLMEALSGISLNGLTIFSFCKTPDLRTPSNLLVLSLALADTGISLNALVAAVSSLLRRWPHGSEGCQVHGFQGFATALASICGSAAVAWGRYHHYCTRRQLAWDTAIPLVLFVWMSSAFWASLPLMGWGHYDYEPVGTCCTLDYSRGDRNFISFLFTMAFFNFLVPLFITHTSYRFMEQKFSRSGHLPVNTTLPGRMLLLGWGPYALLYLYAAIADVSFISPKLQMVPALIAKTMPTINAINYALHREMVCRGTWQCLSPQKSKKDRTQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P47804-1", "uniprot_id": "RGR_HUMAN", "id": "P47804-1", "name": "RPE-retinal G protein-coupled receptor", "aln": "MAETSALPTGFGELEVLAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLALADSGISLNALVAATSSLLRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHHYCTRSQLAWNSAVSLVLFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDYSKGDRNFTSFLFTMSFFNFAMPLFITITSYSLMEQKLGKSGHLQVNTTLPARTLLLGWGPYAILYLYAVIADVTSISPKLQMVPALIAKMVPTINAINYALGNEMVCRGIWQCLSPQKREKDRTK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: * ***:*:*******:* ***:*****:*** **********:****.:**********:**********.********:**:**:.******.*******.***:*********** ****::*:.******:******:***:*********:*********:***** ******:**** :***** *** :****:.:**** ******.* *********:*****.:***: ************** :********** ****** *** *.** ::***:", "identical_positions": 230, "similar_positions": 43, "identity": "79.04%" }, { "cls_id": "homologset.agr.RGD:1309177", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZIA9-1", "uniprot_id": "D3ZIA9_RAT", "id": "D3ZIA9-1", "name": "Zinc finger protein GLIS2", "aln": "MHSLDEPLDLKLSITKLRAAREKRERTLGVPRHHALH----RELGLVDD---SPTPGSPGSPPPGFLLNPKFPEKLDGRFSAAPLVDLSLSPPSGLDSPNGSSSLSPERQGNGDLPPLPTAVDFQPLRYLDG--VPSSFQFFLPLGSGGALHLPASSFLTPPKDKCLSPELPLAKQLVCRWAKCNQLFELLQDLVDHVNDHHVKP-EQDARYCCHWEGCARHGRGFNASRYKMLIHIRTHTNEKPHRCPTCNKSFSRLENLKIHNRSHTGEKPYVCPYEGCNKRYSNSSDRFKHTRTHYVDKPYYCKMPGCHKRYTDPSSLRKHIKAHGHFVSHEQQE--LLQLRPPPKPPLPTPDSGSYVSGAQIIIP-NPAALFGGPSLPGLP-----LPLAPGPLDLSALACGNGGG--GGGGMGPGLPGSVLPLNLAKNPLLPSPFGAGGLGLPVVSLLGGSAGSKAEGEKGRGSVPARVLGLEDHKTSLERTERSRSRPSPDGLPLLPGTVLDLSTG-NSAASSPEALTPGWVVIPPGSVLLKPAVVN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VDL9-1", "uniprot_id": "GLIS2_MOUSE", "id": "Q8VDL9-1", "name": "Zinc finger protein GLIS2", "aln": "MHSLDEPLDLKLSITKLRAAREKRERTLGVVRHHALH----RELGLVDD---SPAPGSPGSPPPGFLLNPKFPEKVDGRFSAAPLVDLSLSPPSGLDSPNGSSSLSPECQGNGDLPPLPTAVDFQPLRYLDG--VPSSFQFFLPLGSGGALHLPASSFLPPPKDKCLSPELPLAKQLVCRWAKCNQLFELLQDLVDHVNDHHVKP-EQDARYCCHWEGCARHGRGFNA-RYKMLIHIRTHTNEKPHRCPTCNKSFSRLENLKIHNRSHTGEKPYVCPYEGCNKRYSNSSDRFKHTRTHYVDKPYYCKMPGCHKRYTDPSSLRKHIKAHGHFVSHEQQE--LLQLRPPPKPPLPTPDSGSYVSGAQIIIP-NPAALFGGPSLPGLP-----LPLPPGPLDLSALACGNGGG--GGGGIGPGLPGSVLPLNLAKNPLLPSPFGAGGLGLPVVSLLGGSAGSKAEGEKGRGSVPARVLGLEDHKTPLERTERSRSRPSPDGLPLLPGTVLDLSTG-NSAASSPEVLTPGWVVIPPGSVLLKPAVVN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BZE0-1", "uniprot_id": "GLIS2_HUMAN", "id": "Q9BZE0-1", "name": "Zinc finger protein GLIS2", "aln": "MHSLDEPLDLKLSITKLRAAREKRERTLGVVRPRALH----RELGLVDD---SPTPGSPGSPPSGFLLNSKFPEKVEGRFSAAPLVDLSLSPPSGLDSPNGSSSLSPERQGNGDLPPVPSASDFQPLRYLDG--VPSSFQFFLPLGSGGALHLPASSFLTPPKDKCLSPDLPLPKQLVCRWAKCNQLFELLQDLVDHVNDYHVKP-EKDAGYCCHWEGCARHGRGFNA-RYKMLIHIRTHTNEKPHRCPTCSKSFSRLENLKIHNRSHTGEKPYVCPYEGCNKRYSNSSDRFKHTRTHYVDKPYYCKMPGCHKRYTDPSSLRKHIKAHGHFVSHEQQE--LLQLRPPPKPPLPAPDGGPYVSGAQIIIP-NPAALFGGPGLPGLP-----LPLAPGPLDLSALACGNGGGSGGGGGMGPGLPGPVLPLNLAKNPLLPSPFGAGGLGLPVVSLLAGAAGGKAEGEKGRGSVPTRALGMEGHKTPLERTESSCSRPSPDGLPLLPGTVLDLSTGVNSAASSPEALAPGWVVIPPGSVLLKPAVVN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B7D0-1", "uniprot_id": "A0ACD6B7D0_DANRE", "id": "A0ACD6B7D0-1", "name": "Zinc finger protein GLIS2", "aln": "MLSLDEPLDLKVPRGRI-SGRDRGARSPPTLSSSPIHGKGAGQLRMADDGTAVIVPASPASPHTGVLRS-------NSETPTPPAVDLSLSPSS--RNTACSPELS---NGSGSAPVFP--GDSAHIRYVEGGATSQAFQFFVPIGAGGGLHLPSSMFIRQPKDTRASPDLSADEQLACRWRKCHLLFDSLQDLVDHVNDFHVKP-EKDSGYCCHWEGCARKGRGFNA-RYKMLIHIRTHTNEKPHRCPTCNKSFSRLENLKIHNRSHTGEKPYICPYEGCNKRYSNSSDRFKHTRTHYVDKPYYCKMVGCLKRYTDPSSLRKHIKAHGHFVAQEQGGGVGSLIKQSQIAGVGKDSELTYVSGAHIIIPSAAAALLGGHALQGLGGSLPLSPLSPRPLDLSTLGCPNSPT--AGLGGTPILSFSSSPLGLTKSPLLSPSFSSSTLGLPMLPILG-----SERRDHGKG----KIRGEEGEDE-------------------IHGGVLNLSTG-----ASHDPLS--WVVIPSGPVVLKPAVVN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7K0S9-1", "uniprot_id": "GLIS2_DROME", "id": "Q7K0S9-1", "name": "Zinc finger protein GLIS2 homolog", "aln": "-------MDIIQKSIFNSGPHSRGIYEPPLGYFTPYN---------------TPPYIAAYSDSGSWLADHHQHHQQQHQQHQQQMQHIRFPTPP-------ITPPRPIAGYGYRQR--------------------TQSVIMKARGQQDELCRSPVEFPDDSKSCSSSSECGTASDFVCNWTDCDRVFDTLDALAQHVTQRHAIASLTDGLYYCRWRGCQRSERGFNA-RYKMLVHTRTHTKEKPHRCHLCEKSFSRAENLKIHIRSHSGEKPYKCSFEGCQKAYSNSSDRFKHTRTHSMEKPYMCKVAGCQKRYTDPSSLRKHVKTFKHSIHLIASQP-LTLPSVPCLLEASSESAFTCLPAASSVESTSSSSSARYYDDSNNE---------PSDYSLKPKQDAEFSP--------SYWLGDRQHSYLHSEDFFVKMDVESPLDLRIHRI-------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*: . :.: . : :. * . * . : . .: :.... . . :: . * . * .. * .*. *.: .::.*.* .*. :*: *: *.:**.: *. . *. * *:*.** * ***** *****:* ****:****** *.***** ****** ***:***** *.:***:* ************** ::*** **: ** ************:*:. * : . . . :..* : . .:: . * .*.. : . * .. :: . *.* : : ", "identical_positions": 111, "similar_positions": 91, "identity": "20.44%" }, { "cls_id": "homologset.agr.RGD:1309178", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L3P4-1", "uniprot_id": "A0ABK0L3P4_RAT", "id": "A0ABK0L3P4-1", "name": "Regulator of nonsense transcripts 2", "aln": "MKIVLGHIMPAERKKSASMEEKESLLNNKEKDCSERRPVSSKEKSKDDLKITAKKEVSKVPEDKKKKLEEDKRKKEDKERKKKEEEKVKAEEELKKKEEEEKKKQEEEERKKQEEQAKRQQEE-AAAQLKEKEESLQLHQEAWERHQLRKELRSKNQNAPDNRPEENFFSRLDSSLKKNTAFVKKLKT-ITEQQRDSLSHDFNGLNLSKYIAEAVASIVEAKLKIS----DVNCAVHLCSLFHQRY-ADFAPSLLQVWKKHFEAR------KEEKTPNITKLRTDLRFIAELTIVGIFTDKEGLSLIYEQLKSIINADRESHTHVSVVISFCRHCGDDIAGLVPRKVKSAAEKFNLNFPPSE------IISPEKQQPFQNLLKEYFTSLTKHLKRDHRELQNTERQNRRILHSKGELSEDRHKQYEEFAMSYQKLLANSQSLADLLDENMPDLPQDKPTPEEHGPGIDIFTPGKPGEYDLEGGIWEDEDARNFYENLIDLKAFVP---------AILFKDNEKS-QNKDSSKDDSKEAKEPKDNKEASSPDD--LELELENLEINDDTLELEGGDEAEDLTKKLLDEQEQEDEEASTGSHLKLIVDAFLQQLPNCVNRDLIDKAAMDFCMNMNTKANRKKLVRALFIVPRQRLDLLPFYARLVATLHPCMSDVAEDLCSMLRGDFRFHVRKKDQINIETKNKTVRFIGELTKFKMFTKNDTLHCLKMLLSDFSH-HHIEMACTLLETCGRFLFRSPESHLRTSVLLEQMMRKKQAMHLDARYVTMVENAYYYCNPPPAE--KTVRRKRPPLQEYVRKLLYKDLSKVTTEKVLRQMRKLPWQDQEVKDYVICCMINIWNVKYNSIHCVANLLAGLVLYQEDVGIHVVDGVLEDIRLGMEVNQPKFNQRRISSAKFLGELYNYRMVESAVIFRTLYSFTSFGVNPD-GSPSSL---DPPEHLFRIRLVCTILDTCGQYFDRGSSKRKLDCFLVYFQRYVWWKKSLEVWTKDHP----FPIDIDYMISDTLELLRPKIKLCNSLEESIRQVQDLEREFLIKLGLVNDKE--SKDSMTEGENLEEDEEEEEGGAETEEQ----SGNESEVNEPEEEEGSD--------DEDEGEEEEEENTDYLTDSNKENETDEENAEVMIKGGGLKHVPCVEDEDFIQALDKMMLEN-LQQRSGESVKVHQLDVAIPLHLKSQLRKGPPLGGGEGETES----------ADTMPFVMLTR--KGNKQQFKILNVPMSSQLAANHWNQQQAEQ-----EERMRMKKLTLDINERQEQEDYQEMLQSLAQR-PAPANTNRERRPRYQHPKGAPNADLIFKTGGRRR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2AT37-1", "uniprot_id": "RENT2_MOUSE", "id": "A2AT37-1", "name": "Regulator of nonsense transcripts 2", "aln": "--------MPAERKKSASMEEKESLLNNKEKDCSERRPVSSKEKPRDDLKVTAKKEVSKVPEDKKKRLEEDKRKKEDKERKKKEEEKVKAEEELKKKEEEEKKKQEEEERKKQEEQAKRQQEE-AAAQLKEKEESLQLHQEAWERHQLRKELRSKNQNAPDNRPEENFFSRLDSSLKKNTAFVKKLKT-ITEQQRDSLSHDFNGLNLSKYIAEAVASIVEAKLKLS----DVNCAAHLCSLFHQRY-SDFAPSLLQVWKKHFEAR------KEEKTPNITKLRTDLRFIAELTIVGIFTDKEGLSLIYEQLKSIINADRESHTHVSVVISFCRHCGDDIAGLVPRKVKSAAEKFNLSFPPSE------IISPEKQQPFQNLLKEYFTSLTKHLKRDHRELQNTERQNRRILHSKGELSEDRHKQYEEFAMSYQKLLANSQSLADLLDENMPDLPQDKPTPEEHGPGIDIFTPGKPGEYDLEGGIWEDEDARNFYENLIDLKAFVP---------AILFKDNEKS-QNKDSNKDDSKEAKEPKDNKEASSPDD--LELELENLEINDDTLELEGADEAEDLTKKLLDEQEQEDEEASTGSHLKLIVDAFLQQLPNCVNRDLIDKAAMDFCMNMNTKANRKKLVRALFIVPRQRLDLLPFYARLVATLHPCMSDVAEDLCSMLRGDFRFHVRKKDQINIETKNKTVRFIGELTKFKMFTKNDTLHCLKMLLSDFSH-HHIEMACTLLETCGRFLFRSPESHLRTSVLLEQMMRKKQAMHLDARYVTMVENAYYYCNPPPAE--KTVRKKRPPLQEYVRKLLYKDLSKVTTEKVLRQMRKLPWQDQEVKDYVICCMINIWNVKYNSIHCVANLLAGLVLYQEDVGIHVVDGVLEDIRLGMEVNQPKFNQRRISSAKFLGELYNYRMVESAVIFRTLYSFTSFGVNPD-GSPSSL---DPPEHLFRIRLVCTILDTCGQYFDRGSSKRKLDCFLVYFQRYVWWKKSLEVWTKDHP----FPIDIDYMISDTLELLRPKIKLCNSLEESIRQVQDLEREFLIKLGLVNDKE--SKDSMTEGENLEEDEEEEEGGAETEEQ----SGNESEVNEPEEEEGSE--------EEEEGEEEEEENTDYLTDSNKENETDEENAEVMIKGGGLKHVPCVEDEDFIQALDKMMLEN-LQQRSGESVKVHQLDVAIPLHLKSQLRKGPPLGGGEGETES----------ADTMPFVMLTR--KGNKQQFKILNVPMSSQLAANHWNQQQAEQ-----EERMRMKKLTLDINERQEQEDYQEMLQSLAQR-PAPANTNRERRPRYQHPKGAPNADLIFKTGGRRR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HAU5-1", "uniprot_id": "RENT2_HUMAN", "id": "Q9HAU5-1", "name": "Regulator of nonsense transcripts 2", "aln": "--------MPAERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKT-ITEQQRDSLSHDFNGLNLSKYIAEAVASIVEAKLKIS----DVNCAVHLCSLFHQRY-ADFAPSLLQVWKKHFEAR------KEEKTPNITKLRTDLRFIAELTIVGIFTDKEGLSLIYEQLKNIINADRESHTHVSVVISFCRHCGDDIAGLVPRKVKSAAEKFNLSFPPSE------IISPEKQQPFQNLLKEYFTSLTKHLKRDHRELQNTERQNRRILHSKGELSEDRHKQYEEFAMSYQKLLANSQSLADLLDENMPDLPQDKPTPEEHGPGIDIFTPGKPGEYDLEGGIWEDEDARNFYENLIDLKAFVP---------AILFKDNEKSCQNKESNKDDTKEAKESKENKEVSSPDD--LELELENLEINDDTLELEGGDEAEDLTKKLLDEQEQEDEEASTGSHLKLIVDAFLQQLPNCVNRDLIDKAAMDFCMNMNTKANRKKLVRALFIVPRQRLDLLPFYARLVATLHPCMSDVAEDLCSMLRGDFRFHVRKKDQINIETKNKTVRFIGELTKFKMFTKNDTLHCLKMLLSDFSH-HHIEMACTLLETCGRFLFRSPESHLRTSVLLEQMMRKKQAMHLDARYVTMVENAYYYCNPPPAE--KTVKKKRPPLQEYVRKLLYKDLSKVTTEKVLRQMRKLPWQDQEVKDYVICCMINIWNVKYNSIHCVANLLAGLVLYQEDVGIHVVDGVLEDIRLGMEVNQPKFNQRRISSAKFLGELYNYRMVESAVIFRTLYSFTSFGVNPD-GSPSSL---DPPEHLFRIRLVCTILDTCGQYFDRGSSKRKLDCFLVYFQRYVWWKKSLEVWTKDHP----FPIDIDYMISDTLELLRPKIKLCNSLEESIRQVQDLEREFLIKLGLVNDKD--SKDSMTEGENLEEDEEEEEGGAETEEQ----SGNESEVNEPEEEEGSDN-------DDDEGEEEEEENTDYLTDSNKENETDEENTEVMIKGGGLKHVPCVEDEDFIQALDKMMLEN-LQQRSGESVKVHQLDVAIPLHLKSQLRKGPPLGGGEGEAES----------ADTMPFVMLTR--KGNKQQFKILNVPMSSQLAANHWNQQQAEQ-----EERMRMKKLTLDINERQEQEDYQEMLQSLAQR-PAPANTNRERRPRYQHPKGAPNADLIFKTGGRRR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W3L1-1", "uniprot_id": "Q9W3L1_DROME", "id": "Q9W3L1-1", "name": "", "aln": "--------------------------------------------MLANDSATTDSEVSTPPSSRKD-LADGVAEGDNDNDIDTGDTDANADEDVDAAAAIALEAE-------------------------EREELQQFISELREKIESKRQLR--LQNSTIELPGEEYFAKLDSNLKKNTAFVKKLKL-FTATQLDGLLREISALNLSKYISEICAALVEAKLKMT----DVPAVVTLASRLHCTY-ADFDVHFLEAWQKALNIK------ATEKIGNPSKLRVDLRLFAELVSSGVIQMKPGLAQLGVVLVHLIALDKDDHSNFSIILSFCRHCGEEYAGLVPQKMQQLATKYGVEVPKSD------FLTADKQLNLRTMLKGYFKALCKHVLAEQAELMNMTKNIRRTMECKGEISTEKREKCELMQAGFDKLLASAQSLSELLGEPLPELAKE---SEGCNPGTVIDNMLDSASFGVLD-PWGDEETRAFYTDLPDLRQFLPNFSAPKVDLETLEEPSELTEEAIDANLDAEMDLDDPPSTTSDTTPENPIEEQPTTPVAAAEDLKPQKMGNALMELGRQQQQQSQLNQNPIQIQNQMRQQFDGFLVNLFNCVNKELIDSAAIEFLLNFNTKHQRKKLTRTIFSVQRTRLDILPYLSRFVAIVHMCNTDVATDLAELLRKEFKWHIHKKNQLNIETKLKIVRFIGELVKFGLFKKFDALGCLKMLLRDFQH-HQIEMACAFVEVTGVYLYNCRDARLLMNVFLDQMLRLKTATAMDSRHAAQIESVYYLVKPPESS--KREPMVRPAMHEYIRYLIFEELCKQNVDRCIKMLRRIDWQDPETNCYAIKCLSKAYLLRFQLIRCLADLVSGLSSYQPRAVTIVIDNVFEDIRAGLEIHSPRMAQRRIAMAKYLGEMYNYKLVESTNILNTLYSIISLGVSNDQNVVSPL---DPPDSLFRLKLACMLLDTCAPYFTSQATRKKLDYFLVFFQHYYWFKKSHPVFSKTENTSDLFPILMDHTYRDCLLNVRPKLKIYKSLEQAKAAIDHLQEKLYPQLKTTNNAQDPSLGTISEISEIDEGGTDEDSGSSNDQRERQVSGQEQDQSNDWTENEAEPPLPPLPPPEKSKEDLEFEQLYEKMTTDSYQERLKEPIKATAKDIPVPMMARLQKKSYDQITGAQTIGPGINNMSQISKSVPNQDGTPGSPGADSPDGNGKSGGGVGGSDVGAAGAAGASGATSVPFVLMVRGHKGGKQQFKSFVAPSDSHLATNLKRQEQMIR-----EEKEKVKRLTLNITERIEEEDYQESLMPPQHRNFTQSYYQKPNKHKFKHQKGAPDADLIFH------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38798-1", "uniprot_id": "NMD2_YEAST", "id": "P38798-1", "name": "Nonsense-mediated mRNA decay protein 2", "aln": "--------------------------------------------------------------------------MDDGRKKELHDLNTRAWNG---------------------------------------EEVFPLKSK-----------------------------KLDSSIKRNTGFIKKLKKGFVKGSESSLLKDLSEASLEKYLSEIIVTVTECLLNVLNKNDDVIAAVEIISGLHQRFNGRFTSPLLGAFLQAFENPSVDIESERDELQRITRVKGNLRVFTELYLVGVFRTLDDIESKDAIPNFLQKKTGRKDPLLFSILREILNYKFKLG-FTTTIATAFIKKFAPLFRDDDNSWDDLIYDSKLKGALQSLFKNFIDATFARATELHKKVNKLQREHQKCQIRTGKLRDEYVEEYDKLLPIFIRFKTSAITLGEFFKLEIPELEGASNDDLKETASPMITNQILPP----NQRLWENEDTRKFYEILPDISKTVE--------------ESQSSKTEKDSNVNSKN--------------------------------------------------------------------INLFFTDLEMADCKDIIDDLSNRYWSSYLDNKATRNRILKFFMET-QDWSKLPVYSRFIATNSKYMPEIVSEFINYLDNGFRSQLHSN-----KINVKNIIFFSEMIKFQLIPSFMIFHKIRTLIMYMQVPNNVEILTVLLEHSGKFLLNKPEYKELMEKMVQLIKDKKNDRQLNMNMKSALENIITLLYPPSVKSLNVTVKTITPEQQFYRILIRSELSSLDFKHIVKLVRKAHWDDVAIQKVLFSLFSKPHKISYQNIPLLTKVLGGLYSYRRDFVIRCIDQVLENIERGLEINDYGQNMHRISNVRYLTEIFNFEMIKSDVLLDTIYHIIRFGHINNQPNPFYLNYSDPPDNYFRIQLVTTILLNINR--TPAAFTKKCKLLLRFFEYYTFIKEQPLPKETEFRVSSTFKKYENIFGNTKFERSENLVESASRLESLLKSLNAIKSKDDRVKGSSASIHN-GKESAVPIESITEDDEDEDDENDDGVDLLG-EDEDAEISTPNTESAPG-----KHQAKQDESEDEDDEDDDEDDDDDDDDDDDDGEEGDEDDDEDDDDEDDDDEEEEDSDSDLEYGGDLDADRDIEMKRMYEEYERKLKDEEERKAEEELERQFQKMMQ--------------ESIDARKSEKVVASKIPVISKPVSVQKPLLLKKSEEPSSSKETYEELSKPKKIAFTFLTKSGKKTQSRILQLPTDVKFVSDVLEEEEKLKTERNK---IKKIVLKRSFD--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: . . : ...* : ** : .: :***.:*:**.*:**** :. . ..* :::. .*.**::* .::.*. *:: ** ... : * :* : . * :* .: : :: :: . :::: :**.::** *:: .: : ... . :: : . . :.. *: . .: : .. : ::.::* :: : : : :: : :: :: .*:: : :: : : : :: :.: :*.::: :*:* .. * . . * :*::* ** * *: : .: : ::. : .: *: :* . :::**. : : . : :: :* . ** :*::* .::. :: . * *: :::.: : : * : *:.*: ** :: . : :: *: :. :::*: .::* * :* . : : . ::: : * :: . : :*. ** . : .. ::: * *: .:*.. .: :: :*: *:* : : : : : :: * ::.::.** *: :* *:*:*. *:*::. :**: .::* *::*:.:::* :: *:* : :* : * ***: **::*. :* . : :* . :* :*: * : *:. . * : : . :: . **. :: :: : . . . : ..: *. :*:. . ..:: : . *. . ... .: * :: :. :: .: : .. :.:. : . :: . . : .. : : * .:: : * . : . ..:: ** : *:::: : : :: .. * . . :. .: : :: * .:::: ", "identical_positions": 123, "similar_positions": 385, "identity": "9.1%" }, { "cls_id": "homologset.agr.RGD:1309179", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4ACE4-1", "uniprot_id": "D4ACE4_RAT", "id": "D4ACE4-1", "name": "Homeobox protein Hox-D1", "aln": "----MSSYLEYVSCAAGGGSGGVGGDVLGFAPKFCRADARPVALQPAFPLGSGD-------------------GAFVSCLPLAAARPTPSP---------------------------------------------PVAPAQPPGPQPAASRYAPCTLEGAYERGAAPASAA------------------------------EYGFLGSGPAFDFPGALGRAADDSGP-----------HVHYATSAVFSSGG--------------SFLLSGQVDFAAFAEPGPFPACLKEPADGHPG--------------------------------------PFQTVSP-------------APGACPKPASPTSG-------------LPAAHSTFEWMKVKRNAPK---------------------------------------------------------------KSKLSEYGATSPS----------------------SAIRTNFSTKQLTELEKEFHFNKYLTRARRMEIANCLQLNDTQVKIWFQNRRMKQKKREREGLLATAASVASLQLPGSETSPIKSGRNL-------------------GSPSQAQEPS----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q01822-1", "uniprot_id": "HXD1_MOUSE", "id": "Q01822-1", "name": "Homeobox protein Hox-D1", "aln": "----MSSYLEYVSCAAGGGSGGVGGDVLGFAPKFCRADARPVALQPAFPLGSGD-------------------GAFVSCLPLATARPTPSP---------------------------------------------PAGPAQSPVPQPAAPRYAPCTLEGAYERGAAPASAA------------------------------EYGFLGSGPAFDFPGALGRAADEGGA-----------HVHYATSAVFSGGG--------------SFLLSGQVDFAAFGEPGPFPACLKEPADGHPG--------------------------------------PFQTVSP-------------APGACPKPASPTSS-------------LPAAHSTFEWMKVKRNAPK---------------------------------------------------------------KSKLSEYGATSPP----------------------SAIRTNFSTKQLTELEKEFHFNKYLTRARRIEIANCLQLNDTQVKIWFQNRRMKQKKREREGLLATAASVASIKLPRSETSPIKSGRNL-------------------GSPSQAQEPS----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9GZZ0-1", "uniprot_id": "HXD1_HUMAN", "id": "Q9GZZ0-1", "name": "Homeobox protein Hox-D1", "aln": "----MSSYLEYVSCSS---SGGVGGDVLSLAPKFCRSDARPVALQPAFPLGNGD-------------------GAFVSCLPLAAARPSPSP---------------------------------------------PAAPARPSVPPPAAPQYAQCTLEGAYEPGAAPAAAAGG---------------------------ADYGFLGSGPAYDFPGVLGRAADDGGS-----------HVHYATSAVFSGGG--------------SFLLSGQVDYAAFGEPGPFPACLKASADGHPG--------------------------------------AFQTASP-------------APGTYPKSVSPASG-------------LPAAFSTFEWMKVKRNASK---------------------------------------------------------------KGKLAEYGAASPS----------------------SAIRTNFSTKQLTELEKEFHFNKYLTRARRIEIANCLHLNDTQVKIWFQNRRMKQKKREREGLLATAIPVAPLQLPLSGTTPTKFIKNP-------------------GSPSQSQEPS----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P10105-2", "uniprot_id": "LAB_DROME", "id": "P10105-2", "name": "Homeotic protein labial", "aln": "MMDVSSMYGNHPHHHHPHANAYDGYSTTTASAANASSYFAPQQHQPHLQLQQQQQHQHLQQPQQHLTYNGYESSSPGNYYPQQQAQLTPPPTSSHQVVQQHQQQQQAQQQQLYPHSHLFSPSAAEYGITTSTTTGNPGTPLHPSSHSPADSYYESDSVHSYYATAAVATVAPPSNSSPITAANASATSNTQQQQQQAAIISSENGMMYTNLDCMYPTAQAQAPVHGYAGQIEEKYAAVLHASYAPGMVLEDQDPMMQQATQSQMWHHQQHLAGSYALDAMDSLGMHAHMHHGLPHGHLGNLANNPHQQQPQVQQQQQQPHQQPQHPQNQSPAAHQQHHQNSVSPNGGMNRQQRGGVISPGSSTSSSTSASNGAHPASTQSKSPNHSSSIPTYKWMQLKRNVPKPQAPKLPASGIASMHDYQMNGQLDMCRGGGGGGSGVGNGPVGVGGNGSPGIGGVLSVQNSLIMANSAAAAGSAHPNGMGVGLGSGSGLSSCSLSSNTNNSGRTNFTNKQLTELEKEFHFNRYLTRARRIEIANTLQLNETQVKIWFQNRRMKQKKRVKEGLIPADILTQHSTSVISEKPPQQQQPQPPELQLKSQGSDLGGNELATGAPSTPTTAMTLTAPTSKQS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * :: .. * .. :. . : * ** : * . : .: . * *: :*.* * * :.. ** . * ::.. * .*..: *. : *:: :. :* . .:*. .. . *. **.. *:.. . . *:*. *: . * .. : ..** * ::.** :**: ... :.:*. .:: .*::**::***..* .. : *:: * .: ****:.*************:*******:**** *:**:***************** :***:.: . * ..* : : *:** . . ", "identical_positions": 103, "similar_positions": 109, "identity": "16.38%" }, { "cls_id": "homologset.agr.RGD:1309181", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "G3V9M3-1", "uniprot_id": "G3V9M3_RAT", "id": "G3V9M3-1", "name": "", "aln": "MTAEETVNVKEVEIIKLILDFLNSKKLHISMLALEKESGVINGLFSDDMLFLRQLILDGQWDEVLQFIQPLECMEKFDKKRFRYIILKQKFLEALCVNNAMSAEDEPQHVRFLFLKLEFTMQEAVQCLHALEEYCPSKDDYSKLCLLLTLPRLTNHAEFKDWNPSTARVHCFEEVCVMVAEFIPADRKLSEAGFKASNNRLFQLVMKGLLYECCVEFCQSKATGEEITESEVLLGIDLLCGNGCDDLDLSLLSWLQNLPSSVFSCAFEQKMLNIHVDKLLKPTKAAYADLLTPLISKLSPYPSSPMRRPQSADAYMTRSLNPALDGLTCGLTSHDKRISDLGNKTSPMSHSFANFHYPGVQNLSRSLLLENTECHSIYEESPERSDTPVETQQPVSIEPMCQGSGLEKEPANGAQNPVPAKQQEKNELRDSTEQFQEYYRQRLRYQQHLEQKEQQRQIYQQMLLEGGVNQEDGP-DQQQNLTEQFLNRSIQKLGELNIGMDSLGNEVPVLNQQCLGSKNSGSNNSSVTSFSSPPQDSSQRLTHDTSNIHTSTPRNPGSTNHIPFLEESPCGSQNSSEHSVVKPSPGDSSGSLSRSKGEEDDKSKKQFVCINTLEDTQAVRAVAFHPSGSLYAVGSNSKTLRVCAYP--EKLDTSAHDGPKQPVVRFKRNKHHKGSIYCVAWSPCGQLLATGSNDKYVKVLPFNAETCNATGPDLEFSMHDGTIRDLAFMEGPESGGAILISAGAGDCNIYTTDCQRGQGLHALSGHTGHILALYTWSGWMIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTG---SAVASVAVDPSGRLLATGQEDSSCMLYDIRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDLQGDLTKQLPLMVVGEHKDKVIQCRWHTQDLSFLSSSADRTVTLWTYSG-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CGF6-1", "uniprot_id": "WDR47_MOUSE", "id": "Q8CGF6-1", "name": "WD repeat-containing protein 47", "aln": "MTAEETVNVKEVEIIKLILDFLNSKKLHISMLALEKESGVINGLFSDDMLFLRQLILDGQWDEVLQFIQPLECMEKFDKKRFRYIILKQKFLEALCVNNAMSAEDEPQH-------LEFTMQEAVQCLHALEEYCPSKDDYSKLCLLLTLPRLTNHAEFKDWNPSTARVHCFEEVCVMVAEFIPADRKLSEAGFKASNNRLFQLVMKGLLYECCVEFCQSKATGEEITESEVLLGIDLLCGNGCDDLDLSLLSWLQNLPSSVFSCAFEQKMLNIHVDKLLKPTKAAYADLLTPLISKLSPYPSSPMRRPQSADAYMTRSLNPALDGLTCGLTSHDKRISDLGNKTSPMSHSFANFHYPGVQNLSRSLMLENTECHSIYEESPERSDTPVEAQQPVSSEAMCQGSGLEKEPANGAQNPVPAKQ-EKNELRDSTEQFQEYYRQRLRYQQHLEQKEQQRQMYQQMLLEGGVNQEDGP-DQQQNLTEQFLNRSIQKLGELNIGMDSLGNEVPVLNQQCSGSKNNGSNNSSVTSFSTPPQDSSQRLIHDTANIHTSTPRNPGSTNHIPFHEDSPCGSQNSSEHSVIKPSPGDSSGNLSRSKGEEDDKSKKQFVCINTLEDTQAVRAVAFHPSGSLYAVGSNSKTLRVCAYP--EKMDASAHDNPKQPVVRFKRNKHHKGSIYCVAWSPCGQLLATGSNDKYVKVLPFNAETCNATGPDLEFSMHDGTIRDLAFMEGPESGGAILISAGAGDCNIYTTDCQRGQGLHALSGHTGHILALYTWSGWMIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTG---SAVASVAVDPSGRLLATGQEDSSCMLYDIRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDLQGDLTKQLPLMVVGEHKDKVIQCRWHTQDLSFLSSSADRTVTLWTYSG-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O94967-1", "uniprot_id": "WDR47_HUMAN", "id": "O94967-1", "name": "WD repeat-containing protein 47", "aln": "MTAEETVNVKEVEIIKLILDFLNSKKLHISMLALEKESGVINGLFSDDMLFLRQLILDGQWDEVLQFIQPLECMEKFDKKRFRYIILKQKFLEALCVNNAMSAEDEPQH-------LEFTMQEAVQCLHALEEYCPSKDDYSKLCLLLTLPRLTNHAEFKDWNPSTARVHCFEEACVMVAEFIPADRKLSEAGFKASNNRLFQLVMKGLLYECCVEFCQSKATGEEITESEVLLGIDLLCGNGCDDLDLSLLSWLQNLPSSVFSCAFEQKMLNIHVDKLLKPTKAAYADLLTPLISKLSPYPSSPMRRPQSADAYMTRSLNPALDGLTCGLTSHDKRISDLGNKTSPMSHSFANFHYPGVQNLSRSLMLENTECHSIYEESPER-DTPVDAQRPIGSEILGQSSVSEKEPANGAQNPGPAKQ-EKNELRDSTEQFQEYYRQRLRYQQHLEQKEQQRQIYQQMLLEGGVNQEDGP-DQQQNLTEQFLNRSIQKLGELNIGMDGLGNEVSALNQQCNGSKGNGSNGSSVTSFTTPPQDSSQRLTHDASNIHTSTPRNPGSTNHIPFLEESPCGSQISSEHSVIKPPLGDSPGSLSRSKGEEDDKSKKQFVCINILEDTQAVRAVAFHPAGGLYAVGSNSKTLRVCAYP--DVIDPSAHETPKQPVVRFKRNKHHKGSIYCVAWSPCGQLLATGSNDKYVKVLPFNAETCNATGPDLEFSMHDGTIRDLAFMEGPESGGAILISAGAGDCNIYTTDCQRGQGLHALSGHTGHILALYTWSGWMIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTG---SAVASVAVDPSGRLLATGQEDSSCMLYDIRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDLQGDLTKQLPIMVVGEHKDKVIQCRWHTQDLSFLSSSADRTVTLWTYNG-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1QV96-1", "uniprot_id": "A0A8M1QV96_DANRE", "id": "A0A8M1QV96-1", "name": "", "aln": "MTAEEIINVKEVEIIKVMLDFLNSRKLHISMLALEKESGVINGLYSDDMLFLRQLILDGQWDEVLQFIQPLECLDKFDRKRFRYIVLKQKFLEALCVNNAMSAEDEPQH-------LELTMQEAVKCLHALEEFCPSKDDYSKLCLLLTLPRLTNHAEFKDWNPSTARVQCFEESCGMVAEFIPADRKLSEAGFRASSNRLFQLLIKGVLYECCVEFCQSKATGEEITESEVLLGIDMLCGNGCDDLDLSLLSWLQNLSPSVFSCAFEQKMLNIHVDRLVKPAKAAYADLLTPLISKLSPYPASPLRRPQSADTYMSRSLNPALDGLSYGLSQEKRGVTTDGGKTSPMSHSFANFQH-----MNRSVMMENSGCHSIFEESPESSRTETPSDKMMSSPGP-QNS--RPASAPGQDAPTPGSE-EKNELRDSTDQFQEYYRQRLRVQQHLEQKQQQRELYQQMLREGGVQQHEAPPTAKHNLTEAFLTRSIQRLEELNVGMDDLGEEVQALSQQCKEGTNS---NGEVGDASATPQTQDG--GGGASSVMTSTPQRSASQSGFPPSSQSPVLTKSAQKD---KTGQNDS---LTRSKGPEKEKTKAKFVMVNTLEDTQAVRAVAFHPTGALYAVGSNSKTLRVCAYP--DTLDTSGTGTNKPPVIRFKRNKHHKGSIYCVAWSPCGQLLATGSNDKYVKVLPFNPETCNATGPDLEFSMHDGTIRDLAFMEGPECGGAILISAGAGDCNIYTTDCQRGQGLHALSGHTGHILSLYTWGGWMIASGSQDKTVRFWDLRVPSCVRVVGTAFQGSG---SPVASVAVDPSGRLLATGQEDSSCMLYDIRGGRMVQTYKPHSSDVRSVRFSPGAHYLLTGSYDNKVIVTDLQGDLTKQLPLTVVGEHGDKVIQCRWHSHHLSFLSSSADRTVTLWTQAT-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W1G4-1", "uniprot_id": "Q9W1G4_DROME", "id": "Q9W1G4-1", "name": "Nucleolar protein 10-like N-terminal domain-containing protein", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNPESRD-------------------------------LDLRKG---DVERPHFEAVTTLSDSQAIRSVDFHPNGKLYAVGSNSKTFRICQYPALSKLRHGHQAAVYPPSVLCKRTKHHRGSIYCTCWSRDGELIATGSNDKTIKYMRFNNDTNQLVGHEMELNMHDGTVRDMCFLDDSSTKSRLLASGGAGDCKIYITDCGTGTPFQAYSGHTGHILSLYSWNNAMFVSGSQDQTIRFWDLRVNVSVNTLDNDRKDGGLESSAVTAVCVDPTGRLLVSGHADSSCTLYDIRGNRPIQRFYPHTAEIRCVRFSPSAYYMLTCSYDNSIRLTDLQGDLAHELSSVVVAEHKDKAITIRWHPTEFSFISTSADKTATLWALPPS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. * . * ** : : :* :. *.*:**:*:* *** * **********:*:* ** . : . * : **.***:*****..** *:*:******* :* : ** :* : .* ::*:.*****:**:.*::... . :* *.*****:** *** * ::* ********:**:*.. *:.*****:*:******* .*..:.. :. * *.*::*.***:****.:*: **** ******.* :* : **::::*.*****.*:*:** *** .: :*******:::*. **.** **.* ***. .:**:*:***:*.***: ", "identical_positions": 172, "similar_positions": 99, "identity": "18.4%" }, { "cls_id": "homologset.agr.RGD:1309183", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AJG9-1", "uniprot_id": "A0A8I6AJG9_RAT", "id": "A0A8I6AJG9-1", "name": "Ankyrin repeat and SAM domain-containing protein 1A", "aln": "MGKEQELLEAARTGHLPAVEKLLSGKRLSSGFGGGGGGGSGSGGGS---GGGGLGSSSHPLSSLLSMWRGPNVNCVDSTGYTPLHHAALNGHRDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIVRLLIHQGPSHTRVNEQ---------------------NNDNETALHCAAQYGHTEVVKALLEELTDPTMRNNKFETPLDLAALYGRLEVVKLLLSAHPNLLSCS---------------------TRKHTPLHLAARNGHKAVVQVLLDAGMDSNYQTEMGSALHEAALFGKTDVVQILLAAGIDVNIKDNRGLTALDTVRDLPSQKSQQIAALIEDHMTGRRSVKDVDKTSTAQLPLLSCTDAIAPKSLGSVEKAVTEPTLDSDILAEEEGPYEALYNAVSCHSLDSTASGRSSDRDSVNKEAEATGARAAGVRPRERPPPPAKPPPDEEEEERVDKKYLPLAASEGLALRPRMQGSAPQEEEEHPYELLLTAETKKLGTTDG---------RTEDHRQSGGSRSQDSVEGQDGQVPEQFSGLLHGSSPVCEVGQDPFQLLTVPSQNHPE-SSQQDACQEASMQLEEPGEQSTGAPQPGILDQSKRAGLSAGLTALASRTYLDALTHTVPLHPAGAEEED--GSRSRAPPTSKPKAELKLSRSLSKSDSD--------------------LLTCSPTEDT-TMGSRSESLSNCSIGKKRLEKSPSFASEWDEIEKIMSSIGEGIDFSQEQQ----------------------------KISGSRTLEQSVGEWLESIGLQQYESKLLLNGFDDVRFLGSNVMEDQDLREIGISD-------------------PQHRRKLLQAARSLPKVKALGYDGVSPASVPSWLDSLG---------------LQDYIHSFLSSGYSSIDTVKNLWELELVNVLKVHLLGHRKRIIASLADRPYEEPPQKPPRFSQLRCQDLISQTSSPLSQNDSCTGR------------------------------------------------------------------------------------------------------------------------SADLLLPSVDTSRRRHDSLHDPGTTSR---------------------------------------AEHFRVQEEPSESK-LTLRPPSLAAPYAPVQSWQHRPEKLIFESCGYEANYLGSMLIKDLRGTESTQDACAKMRKSTEHMKKIPTIILS----------------------------ITYKGVKFMDASNKNVIAEHEIRNISCAAQDPEDLCTFAYITKDLQTSHHYCHVFSTVDVNLTYEIILTLGQAFEVAYQLALQAQKSR---TMAASAASMIETKSSKPVPKPRVGMRKSAVPVPPDSRCCHCHTCTTHRPSYLPLPSVSP----------GAKLEPPDSDQEAPSHASVSWIVDPKPDSKRSLSTN----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P59672-1", "uniprot_id": "ANS1A_MOUSE", "id": "P59672-1", "name": "Ankyrin repeat and SAM domain-containing protein 1A", "aln": "MGKEQELLEAARTGHLPAVEKLLSGKRLSSGFGGGGGG-SGSGGGS---GGGGLGSSSHPLSSLLSMWRGPNVNCVDSTGYTPLHHAALNGHRDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIVRLLIQQGPSHTRVNEQNALEIRELKKYGPFDPYINAKNNDNETALHCAAQYGHTEVVKALLEELTDPTMRNNKFETPLDLAALYGRLEVVKLLLGAHPNLLSCS---------------------TRKHTPLHLAARNGHKAVVQVLLDAGMDSNYQTEMGSALHEAALFGKTDVVQILLAAGIDVNIKDNRGLTALDTVRDLPSQKSQQIAALIEDHMTGKRSVKEVDRTSTAQLPLLSNTDAIAPMSQGSMEKTVTELILHFDTHADEEGPYEALYNAVSCHSLDSTASGRSSDRDSMNKEAEATGTRAAGVRPRERPPPPAKPPPDEEEEERVDKKYFPLAASEGLAVRPRIQSSAPQEEEEHPYELLLTAETKKLGTTDG---------RTEDHRQSGSGRSQDSVEGQDGQVPEQFSGLLHGSSPVCEVGQDPFQLLTAPSQSHPE-SSQQDACHEASMQLEEPGVQGTEPPQPGVPDQSKRVGLPAGLTALASRTYLDALTHTVPLRPAGAEEEDQSGPRSRAPPTSKPKAELKLSRSLSKSDSD--------------------LLTCSPTEDA-TMGSRSESLSNCSIGKKRLEKSPSFASEWDEIEKIMSSIGEGIDFSQEQQ----------------------------KISGSRTLEQSVGEWLESIGLQQYESKLLLNGFDDVRFLGSNVMEEQDLREIGISD-------------------PQHRRKLLQAARSLPKVKALGYDGVSPTSVPSWLDSLG---------------LQDYVHSFLSSGYSSIDTVKNLWELELVNVLKVHLLGHRKRIIASLADRPYEEPPQKPPRFSQLRCQDLISQTSSPLSQNDSCTGR------------------------------------------------------------------------------------------------------------------------SADLLLPSADTSRRRHDSLPDPGTASR---------------------------------------ADRFRVQEEPSETK-LTLRPPSLAAPYAPVQSWQHQPEKLIFESCGYEANYLGSMLIKDLRGTESTQDACAKMRKSTEHMKKIPTIILS----------------------------ITYKGVKFIDASNKNVIAEHEIRNISCAAQDPEDLCTFAYITKDLQTSHHYCHVFSTVDVNLTYEIILTLGQAFEVAYQLALQAQKSR---TMAASAASMIETKSSKPVPKPRVGMRKSAL-------------------------------------------EPPDSDQEAPSHASVSWIVDPKPDSKRSLSTN----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92625-1", "uniprot_id": "ANS1A_HUMAN", "id": "Q92625-1", "name": "Ankyrin repeat and SAM domain-containing protein 1A", "aln": "MGKEQELLEAARTGHLPAVEKLLSGKRLSSGFGGGGGGGSGGGGGGSGGGGGGLGSSSHPLSSLLSMWRGPNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIVRLLIHQGPSHTRVNEQ---------------------NNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKMLLNAHPNLLSCN---------------------TKKHTPLHLAARNGHKAVVQVLLDAGMDSNYQTEMGSALHEAALFGKTDVVQILLAAGTDVNIKDNHGLTALDTVRELPSQKSQQIAALIEDHMTGKRSTKEVDKTPPPQPPLISSMDSISQKSQGDVEKAVTELIIDFDANAEEEGPYEALYNAISCHSLDSMASGRSSDQDSTNKEAEAAGVKPAGVRPRERPPPPAKPPPDEEEEDHIDKKYFPLTASEVLSMRPRIHGSAAREEDEHPYELLLTAETKKVVLVDG---------KTKDHRRSSSSRSQDSAEGQDGQVPEQFSGLLHGSSPVCEVGQDPFQLLCTAGQSHPDGSPQQGACHKASMQLEETGVHAPGASQPSALDQSKRVGYLTGLPTTNSRSHPETLTHTASPHPGGAEEGDRSGARSRAPPTSKPKAELKLSRSLSKSDSD--------------------LLTCSPTEDA-TMGSRSESLSNCSIGKKRLEKSPSFASEWDEIEKIMSSIGEGIDFSQERQ----------------------------KISGLRTLEQSVGEWLESIGLQQYESKLLLNGFDDVHFLGSNVMEEQDLRDIGISD-------------------PQHRRKLLQAARSLPKVKALGYDGNSPPSVPSWLDSLG---------------LQDYVHSFLSSGYSSIDTVKNLWELELVNVLKVQLLGHRKRIIASLADRPYEEPPQKPPRFSQLRCQDLLSQTSSPLSQNDSCTGR------------------------------------------------------------------------------------------------------------------------SADLLLPPGDTGRRRHDSLHDPAAPSR---------------------------------------AERFRIQEEHREAK-LTLRPPSLAAPYAPVQSWQHQPEKLIFESCGYEANYLGSMLIKDLRGTESTQDACAKMRKSTEHMKKIPTIILS----------------------------ITYKGVKFIDASNKNVIAEHEIRNISCAAQDPEDLCTFAYITKDLQTSHHYCHVFSTVDVNLTYEIILTLGQAFEVAYQLALQAQKSR---ATGASAAEMIETKSSKPVPKPRVGVRKSAL-------------------------------------------EPPDMDQDAQSHASVSWVVDPKPDSKRSLSTN----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q0Z5-1", "uniprot_id": "A0A8M9Q0Z5_DANRE", "id": "A0A8M9Q0Z5-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSQNVG----------------QASYPEHIETNGS---------------------------SEEAPNGR-------LKVISRSDSD--------------------LLASLDCEDVGPVFGQSDSLSDYAAQRKETEQMPSLDSEWDEIERIMTLIAG-IEIPEERQPALE------------------------DAAGSRVLEQSVGEWLEHVGFPQYESKLVLNGFDELRYMGSNVMEDEDLHEIGITD-------------------PGHRKKILHAAKSLPKVKALGCDG--STSLYSWLESLG---------------LGEYLHNFLSSGYRTLECVKNLWELEIVNVLKIGLLGHRKRIIASIAERPYEEAPSKTNRFSQLKIQDLLSQNASPLSYMDPYTSR------------------------------------------------------------------------------------------------------------------------SMDMLLPLGEAGRKSRALDQDGSISLRSF-------------------------------------GERSRSHDRHADRHSRQNRPTSQSHTYTTVSAWHHHPEKLITESCVYEARYLGSVIIRDLRGIESTQEACARIRKSKDHRK-GPVIILN----------------------------ITYKGVKFVDAATKAMVAEHEIQDISCAAQDPDDLCTFAYITKDMKSGYHFCHVFTTVEVTQTYEIILTLGQAFEVAYQMALQAQKARRHSSYAGPAPENIEIKTNRPTSQSRNSTRRSTGAPVLECRCCYCHTCSAHRPSYLPLPSISPGVQSHSSLLLPRQIDPLELETDLQSLGSTSWLYEPRSSSRPSSSTKHLQL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VCM6-1", "uniprot_id": "Q9VCM6_DROME", "id": "Q9VCM6-1", "name": "Ankyrin repeat and SAM domain-containing protein 1A", "aln": "MGKDQEFLEAARNGNISHIEKVLTQK-------------------------------AKRAGPLASLRRGTGVNVQDSGGYSALHHACLNGHEDIVRLLLAHEASPNLPDSRGSSPLHLAAWAGETEIVRLLLTHPYRPASANLQT---------------------IEQETPLHCAAQHGHTGALALLLHHDADPNMRNSRGETPLDLAAQYGRLQAVQMLIRAHPELIAHLGTEALERGTPSPSSPASPSRAIFPHTCLHLASRNGHKSVVEVLLSAGVSVNLLTPSGTALHEAALCGKENVVRTLLKAGINLNATDNEGRTALDILREFPPHVTKHIVAVINNFRNQMDTDEGDEVIYRQHSGPP------NSGRGQNKHHSQQQPPLSNHYHFNSNNHLLNHSHSMQQSGYSKQRLSAGNGGPYNGGKSLDSALQPEDRFYQDLNAHSPLHSQNEMGGGYSVSPSSSLSSFEPASVSPRSRCSTGGLGQPMHMSTFAPAGPPKKPPRRNLSVSPTHAGPGQQFSYSSPSSQSQSQSHGHGQNQVRRQPASESPYSHQSHGSVGGMSFDETQLRERQRNDRLYASARQSTRSAIAGGMSLSSSNDMLDRQCSSSELNSETSVPNSSGDSPATNSMKRPIPAPRSSTTKLSKELLKSAESATLKSYNPNRKLKRNRNSSGANGAAKSNGGDENCEAKQQIPSSPTHYKQPPTPDHPPPSSSQAERTIHERIRPLSQEYKRRSALLQLQAAQQLMIETGSSPSKLLPTLSTPGYDYDDTVTVVPRCPAPSSGSLSSSISCSDHSLSHSTDYVEEFVSDVPFAGLLKGASQQLKEQPEVKLKIQEESKPQQTLPRVRPPIPTKPAIP-EKKFAKPPTTPTNQSLEANGNSSSDVVIKPPRSPSKSPSKTSNKSPVKSPGKSPAKSPGSGHSAARNSINLLSPFNAEEARKKISEIIENFGSGILNTSITPTHDIELDFEDMEVPNERRELATRLRAAGLLHLERILFENGYDNYKFVNNVFEEPDIPLLHIPERDAPKLLRFVQSLPPAEFQPQVPVKTQQENKQMGVATLQQWLNTIALPEYLEFFNKHLYNTIESVCGVWDVELQTVLEINKLGHRRRILQSLAYIRQMRDSDSKSQKTPLGENNETNQLTTNGNGTAREAPPRLPANPVHHRNSITGYRKSRPAPPPPAPPARKTAALQIRAPSELLLGLPANLRTTEWRHSAQTLLNEHINYEVQYLGSTVVKELRGTESTKKSIQKLKTSADGEVKSGSPLS---------------------------LAICHRGVEFKDVNSKRTICEHEIQNINCACQDSEDLRHFAYITKEQD--LHYCHVFLVESTDLASEIILTLGQAFEVAYQLALRDGITTTPELLLDNGMLQGEYCGGK---------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VC09-1", "uniprot_id": "Q9VC09_DROME", "id": "Q9VC09-1", "name": "PID domain-containing protein", "aln": "MGKDQHLLEASRAGDIKTVDKLLEHS-------------------------------SKRHGPLSSFRRSPSINCQDMNGYTSLHHACLNGHSNIVRLLLSHNALLDVPDIRGSTPLFLAAWAGHQDIVKMLLMHSPTGANPNAQT---------------------IENETPLHSGAQHGHNAVVAILLSYGADPAIRNNSFQTALDLAAQFGRLQVVQTLLRVYPDLILPY--KRLEDDNEELLG-CMPIKHIFTHTCLHLASRNGHKKVVETLLAAGVDVNILTNAGSALHEAALCGKKSVVVTLLKAGIYVHATDGNGRTALDILSDYPPHVTYDIVGAINEFTQAAREHQKPLVVENGTQSLP------KRLYEKNSQRQKVPPRQRKKQDHQANG--LSHSLS-----------------------SLDIFAKPPE-NYLQMKPIIHQKSCDNMS-DFRTNGSNLLTSYKPVYKQP-----------------------------------------------MLPSFRMDS---------------------DISNGSVPSRSYEYINLLR---------NGSHSDDNSAS-----TSSNSAVRQQAVATYVEMKLPTP--------------PVPKPR---TRINGEYNDYANVVPIEEGSCVAAVDNNNNSNGNG-------------------TKLRLVRHSPTPDYPPPTVTEAERTIFNFMQPATLRKNS-------------LLEPAESPR--------------------------TTNSVSS-------------DQVEEYVADIPFAGLFKGSTLNLS--SDVVDGIG--------------------AVPGDREFLQSPSMVRSAHVQNHRRSLS---------------------------KQRYSALGEDFSASR-------------VWAEIDTIFENIGN--------------------EVSTVEQEVEEFVEDPSSLSLE-----------------------------------------------------------------------------------------------------------------------------------DSRQ-------------------------------------------------------------SLHIRDPAELLLGRKPSAASSNWCHSPYTFIYGEIRYSLFYLGSTVIRKLQGTLSTRKSIQKLKIDEN--LKSAASVSDFSLLENCTTSTKYLKAANHQTRLNVDIAVSCVGVKFIDHDKKTAICCHDIENINCVCQDSEDLRYFAYITKEQD--LHYCHVFMVDSLELAKEIIMTLGQAFEVAYQLALSR-----------QGTSLNEEC------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . :... .. . . : :. : . . . : : . :. *. : * : .: :. * . : : . : : . . . . .... : : :.: . : : . . . : . . * * . .:: *. **** :::.*:* **:.: ::: . : : : **:* * .* :. *:*.:*.*..**.:** ******: . *:**** . . : ***:***********:** . * ", "identical_positions": 55, "similar_positions": 98, "identity": "3.65%" }, { "cls_id": "homologset.agr.RGD:1309184", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "B1WC86-1", "uniprot_id": "MPPE1_RAT", "id": "B1WC86-1", "name": "Metallophosphoesterase 1", "aln": "-----------------------MALVRWGLRRQNFHLLRRRR-VLLLKLTVVVISVLLFCEYFIYYLVLFRCHWPEVKMPARGGRQ---EPVLKAMFLADTHLLGEIRG-------HWLDKLRREWQMERAFQTALWLLQPEVVFILGDVFDEGKWSSAQAWADDLHRFQRMFR-HGSHVQLKVVIGNHDIGFHYQMSKYRINRFEKVF--GSERLFSLKGVNFVMVNSVAMEGDGCTICSEAEAELREISRKLNCSQEQVQGSSQCDHEP--RLPLSAPVLLQHYPLYRASDANCSGEDAAPPEERSVPFEEKYD-VLSREASQKLLWWLRPRLILSGHTHSACEVLHPGGAP------------------EVSVPSFSWRNRNNPS-----FIMGSLTSRDYALSKCYLPCEDTVLTTYCAAAAFLLVLILAHFERLPSSFLFGWKLCRSHLRR-------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80XL7-1", "uniprot_id": "MPPE1_MOUSE", "id": "Q80XL7-1", "name": "Metallophosphoesterase 1", "aln": "-----------------------MALVRWGLKRQNFHPLRRRRRALLLKLTVVIISVLLFCEYFIYYLVLFRCHWPEVKTLAHGGRQ---EPVLKAMFLADTHLLGEIRG-------HWLDKLRREWQMERAFQTALWLLQPEVVFILGDIFDEGKWSSDQAWADDVQRFQRMFR-HDSHVQLKVVIGNHDVGFHYQMSKYRIKRFEKVF--GSERLLSLKGVNFVMVNSVAMEGDGCIICSEEEAELREISRKLNCSQE-VPGSSQCDREPEPRLPLSAPVLLQHYPLYRASDANCSGEDAAPPEERNVPFEEKYD-VLSREASQKLLWWLRPRLVLSGHTHSACEVLHPGGAP------------------EVSVPSFSWRNRNNPS-----FIMGSLTSRDYALSKCYLPFEDTVLTMYGAAAGFLMILILVHFEHLPSPFLCGWKLCRLHMRR-------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q53F39-1", "uniprot_id": "MPPE1_HUMAN", "id": "Q53F39-1", "name": "Metallophosphoesterase 1", "aln": "-----------------------MAMIELGFGRQNFHPLKRKS-SLLLKLIAVVFAVLLFCEFLIYYLAIFQCNWPEVKTTASDGEQTTREPVLKAMFLADTHLLGEFLG-------HWLDKLRREWQMERAFQTALWLLQPEVVFILGDIFDEGKWSTPEAWADDVERFQKMFR-HPSHVQLKVVAGNHDIGFHYEMNTYKVERFEKVF--SSERLFSWKGINFVMVNSVALNGDGCGICSETEAELIEVSHRLNCSRE-ARGSSRCGPGP--LLPTSAPVLLQHYPLYRRSDANCSGEDAAPAEERDIPFKENYD-VLSREASQKLLWWLQPRLVLSGHTHSACEVHHGGRVP------------------ELSVPSFSWRNRNNPS-----FIMGSITPTDYTLSKCYLPREDVVLIIYCGVVGFLVVLTLTHFGLLASPFLSGLNLLGKRKTR-------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q566Y9-1", "uniprot_id": "MPPE1_DANRE", "id": "Q566Y9-1", "name": "Metallophosphoesterase 1", "aln": "-----------------------MTLVFGSSCR------------LAVTLIFAFVSVFVFCEYVIYYLVILRCSWPLLEIEDS-------HSPLRALFLSDTHLLGAIRG-------HWLDKLRREWQMERAFQTSMWLLNPEVVFILGDVFDEGKWSTSQDWEDDVRRFKRIFR-HPVDTKLVVLVGNHDIGFHHEMTKQKLERFEQVFNVTSARILTIKGVNFLLVNSVALHGDHCPICQHVEEELQKLSHALNCSIQGAQHNGQCKNAA--RFAPAAPVLLQHYPLYRVSDAMCTGVDTAPLDEQYLLFQERYD-VISKNASKKLLWWFKPRLILSGHTHNGCEVLHEKLYP------------------EISVPSFSWRNRNNPS-----FVLGTFSQSEFQLSKCFLPEERTVLVVYCSSCLIIALITLIHLKMFRNSLQFTNNLIGKHKTL-------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VLR9-1", "uniprot_id": "MPPE1_DROME", "id": "Q9VLR9-1", "name": "Metallophosphoesterase 1 homolog", "aln": "-------------------------------MR------------FLYACFVIVLCALIFCEYVADFVVLQKCKWPEIKRKKY------VDDPLRAMILADPHLLGPHRG-------HWLDKLYREWHMTRAFQAASRLFQPDVVFVLGDLFDEGDMVSDKQFQEYVWRYLKMFH-LPPGIPLISVAGNHDVGFHYKMHPFFMSRFESYLNNSSVNLYTIKQIHFVVINSMAMEGDGCMFCTQAEDQLKNISRTLYCMKY--PLEAECARTR--RHPYSQPILLQHFPTYRISDTMCEEHDAPYIEA----FRERFH-VLSKDATDMLGELLKPRLAFAGHSHHFCHSVNRLGID------------------EYTVASFSWRNKVNPS-----FMLATITPDDYVVSKCKMLPQQFVFNSYLSAGILCLIVIGFQLRKCIQSRRQSSAVDHRKVNYLD-----------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40986-1", "uniprot_id": "CDC1_YEAST", "id": "P40986-1", "name": "Cell division control protein 1", "aln": "MVYRNRSKSVLSTHSKKSDDKAHYKSRSKKKSKSRSKKRLRIYWRYISIVWILWLGLISYYESVVVKRAMKKCQWSTWEDWPEG------AESHRVGLFADPQIMDEYSYPGRPQIVNYFTRVIVDHYHRRNWKYVQYYLDPDSNFFLGDLFDGGRNWDDKQWIKEYTRFNQIFPKKPLRRTVMSLPGNHDIGFGDTVVESSLQRFSSYFG-ETSSSLDAGNHTFVLLDTISLSDKTNPNVSRVPRQFLDN--------------FAMGSHP------LPRILLTHVPLWRDPEQQTCGQLRESKEPFPIQKGHQYQTVIENDISQEILTKIQPEILFSGDDHDHCQISHSYPFQGKTKNAQEITVKSCAMNMGISRPAIQLLSLYNPSDLTMVNAGGEYASKTYQTELCYMPDPYKAIRMYLWGLLFSAAFIAYMHFFPKSFNNRVATIMNRVFTRPDGNTSDLPLPTSISKSKSKKSLTHSKYAVNDTRSIKQFLVNAIVLFVSVMPIFIYFYTVV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : : * . .: :* *. : :. :::*.:::. ::: :: : * :: ::*: *.***:** * : : . *: ::* : : ****:** : :.**.. : : *:::::::: .. . :: . :** * * :* .: : ..:. *:..: :. : ::*.: ::*. * *. : : .::. . *** . : : . * : .: * : . . : ", "identical_positions": 39, "similar_positions": 105, "identity": "7.53%" }, { "cls_id": "homologset.agr.RGD:1309185", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Y5Q9-1", "uniprot_id": "TF3C3_HUMAN", "id": "Q9Y5Q9-1", "name": "General transcription factor 3C polypeptide 3", "aln": "-MSGFSPELIDYLEGKISFEEFERRREERKTREKKSLQEKGKLSAEENPDDSEVPSSSGINSTKSQDKDVNEGETSDGVRKSVHKVFASMLGENEDDEEEEEEEEEEEEEEETPEQPTAGDVFVLEMVLNRETKKMMKEKRPRSKLPRALRGLMGEANIRFARGEREEAILMCMEIIRQAPLAYEPFSTLAMIYEDQGDMEKSLQFELIAAHLNPSDTEEWVRLAEMSLEQDNIKQAIFCYTKALKYEPTNVRYLWERSSLYEQMGDHKMAMDGYRRILNLLSPSDGERFMQLARDMAKSYYEANDVTSAINIIDEAFSKHQGLVSMED-----------------------------------------------------VNIAAELYISN--------KQYDKALEIITDFSGIVLEKKTSEEGTSEENKAPENVTCTIPDG-------VPIDITVKLMVCLVHLNILEPLNPLLTTLVEQNPEDMGDLYLDVAEAFLDVGEYNSALPLLSALVCSERYNLAVVWLRHAECLKALGYMERAAESYGKVVDLAPLHLDARISLSTLQQQLGQPE------------KALEALEPMYDPDTLAQDANAAQQELKLLLHRSTLLFSQGKMYG------------------YVDTLLTMLAMLLKVAMNRAQVCLISSSKSGE--------RHLYLIKVSRDKISDSNDQESANCDAKAIFAVLTSVLTKD--------------------------DWWNLLLKAIYSLCDLSRFQEAELLVDSSLEYYSFYDDRQKRKELEYFGLSAAILDKNFRKAYNYIRIMVMENVNKPQLWNIFNQVTMHSQDVR-------HHRFCLRLMLKNPENHALCVLNGHN-------------------------AFVSGSFKHALGQYVQAFRTHPDEPLYSFCIGLTFIHMASQKYVLRRHALIVQGFSFLNRYLSLRG------PCQESFYNLGRGLHQLGLIHLAIHYYQKALELPPLVVEGIELDQLDLRRDIAYNLSLIYQSSGNTGMAQTLLYTYCSI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D4A7Q9-1", "uniprot_id": "D4A7Q9_RAT", "id": "D4A7Q9-1", "name": "", "aln": "-MSGFSPELIDYLEGKISFEEFERRREERKTREKKSVQEKGKSSPKENPGDAEVPSSSGIDSAKSQDRDANEGETSDGVSKSVHKVFASMLGETE---EEEEEEEEEEEEEDTPEQPTAGDVFVLEMVLNRETKKMMKEKRPRSKLPRALRGLMGEANIRFARGEHEEAILMCMEIIRQAPLAYEPFSTLAMIYEDQGDMEKSLQFELIAAHLNPSDTEEWVRLAEMSLEQDNIKQAIFCYTKALKYEPTNVRYLWERSSLYEQMGDHKMAMDGYRRILNLLSPSDGERFMQLARDMAKSYYEANDSTSAINIIEEAFSKHQGLVSMED-----------------------------------------------------VNIAAELYISN--------KQYDKALEVITDFSGIILEKETLEEGTSEENKAAETVTCSIPDS-------VPIDITVKLMVCLVHLNILEPLNPLLTTLVEQNPEDMGDLYLDVAEAFLDVGEYNSALPLLSALVCSERYNLAVVWLRHAECLKALGYMERAAESYSKVVDLAPLHLDARISLSILQQQLGRPE------------KALEALEPMYDPDTLAQDANAAQQELKLLLHRSTLLFSQGKMYG------------------YLDTLLTMLAMLLKVAMNRAQVCLISSSKSGE--------RHLYLIKVSRDKISDNNEQETSNYDAKAIFAVLTSVLPKD--------------------------DWWNLLLKAIYTLSDLSRFQEAELLVDSSLEYYSFYDDRQKRKELEYFGLSAAILDKNFRKAYDYIRVMVMENVNKPQLWNIFNQVTMHSQDVR-------HHRFCLRLMLKNPDNHALCVLNGHN-------------------------AFVSGSFKHALGQYVQAFRAYPSEPLYNLCIGLTFIHMASQKYVLKRHALTVQGFSFLNRYLSIRG------PCQESFYNLGRGLHQLGLTHLAIHYYQKALALPPIVVEGIEVDQLDLRRDIAYNMSLIYQSSGNTAMAQKLLYTYCVI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P33339-1", "uniprot_id": "TFC4_YEAST", "id": "P33339-1", "name": "Transcription factor tau 131 kDa subunit", "aln": "MAAGKLKKEQQNQSAERESADTGKVNDEDEEHLYGNIDDYKHLIQDEEYDDEDVP----------HDLQLSEDEYNSERDSSLLAEFS------------DYGEISEDDEEDFMNAIREASNFKVKKKKKNDKGKSYGRQRKERVLDPEVAQLLSQANEAFVRNDLQVAERLFNEVIKKDARNFAAYETLGDIYQLQGRLNDCCNSWFLAAHLNASDWEFWKIVAILSADLDHVRQAIYCFSRVISLNPMEWESIYRRSMLYKKTGQLARALDGFQRLY-MYNPYDANILRELAILYVDYDRIEDSIELYMKVFNANVERREAILAALENALDSSDEESAAEGEDADEKEPLEQDEDRQMFPDINWKKIDAKYKCIPFDWSSLNILAELFLKLAVSEVDGIKTIKKCARWIQRRESQTFWDHVPDDSEFDNRRFKNSTFDSLLAAEKEKSYNIPIDIRVRLGLLRLNTDNLVEALNHFQCLYDETFSDVADLYFEAATALTRAEKYKEAIDFFTPLLSLEEWRTTDVFKPLARCYKEIESYETAKEFYELAIKSEPDDLDIRVSLAEVYYRLNDPETFKHMLVDVVEMRKHQVDETLHRISNEKSSNDTSDISSKPLLEDSKFRTFRKKKRTPYDAERERIERERRITAKVVDKYEKMKKFELNSGLNEAKQASIWINTVSELVDIFSSVKNFFMKSRSRKFVGILRRTKKFNTELDFQIERLSKLAEGDSVFEGPLMEERVTLTSATELRGLSYEQWFELFMELSLVIAKYQSVEDGLSVVETAQEVNVFFQDPERVKMMKFVKLAIVLQMDDEEELAENLRGLLNQFQFNRKVLQVFMYSLCRGPSSLNILSSTIQQKFFLRQLKAFDSCRYNTEVNGQASITNKEVYNPNKKSSPYLYYIYAVLLYSSRGFLSALQYLTRLEEDIPDDPMVNLLMGLSHIHRAMQRLTAQRHFQIFHGLRYLYRYHKIRKSLYTDLEKQEADYNLGRAFHLIGLVSIAIEYYNRVLEN---------YDDGKLKKHAAYNSIIIYQQSGNVELADHLMEKYLSI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* : : ..: . : : .:* : : .::: : .*: .* :** :* : .*.* .. .*: *: : * .*::**: : .. * :: :.:. * .:* . * : *:.:** *.*.: : * : *:*:: . : .:.**. **: ** ::.. : ::*****.** * * :* :* : *:::***:*:::.:. :* : . ::.** **:: *: *:**::*: : .* *.: : :** .. :. ::::: ..:::.::: : :** ***::. * .*. . * .. : ... ::. ::.: :.. :: . :**** *:* : :: : * : * ::. .*:.***::.* *: . :*:.*: :::.*:. *.:. : *: *.* * : * * * * .:. * .** *:**: : :*. ** : :. *.:: .. .. :::: . * **. *.: : * :*. .* : *: .:*.*: . * .. .* ::::: . **. :. . :. * : . : *:.: * :*::*::: :.. . .::. :*::: * *::* :: * :::. *: .: .: .: : :* :: : : :: ::* :. . :::* ** : . : :**: : * .* ** .: . *.:*: .: :**:.** * *: . :** .:*: :* ** .:* **: *****.:* :** :**.**::.* *: .*::. *** :***.***. :*: *: .* *", "identical_positions": 188, "similar_positions": 343, "identity": "17.79%" }, { "cls_id": "homologset.agr.RGD:1309186", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8C0P0-1", "uniprot_id": "GWL_MOUSE", "id": "Q8C0P0-1", "name": "Serine/threonine-protein kinase greatwall", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MESASASE-ENEGGAAIEE----------CVSRIPVPRPPSIEEFTIVKPISRGAFGKVYLGQK--GGKLYAVKVVKKADMINKNMTHQVQAERDALALSKS-PFVVHLYYSLQSASNIYLIMEYLIGGDVKSLLHIYGYFDEEMAIKYISEVALALDYLHRHGIIHRDLKPDNMLISNEGHIKLTDFGLSKVTLNR-------------------------------DINMMDILTTPSMSKPKQDYSRTPGQVLSLISSLGFFTPVGEKDQDSAN------MFSAPKSA---AQLSRGFICPMSVDQKEP--------TSYSSKLLKSCFETLSSNPEIPVKCLTSNLLQCRKRLGTSST-SSQSHTFVSS----VESECHSNPKWERDCQSTESSG--CAMSWNAVEMLYAKSTSAIKTK--------TELELALSPIHDSS--------------------------------------------AIPAAGSNQVTLPRKCF-REISWEARDPDNENMTIDKG---QSGFCQSS----QRSVNSSATSEEHLG--KRNYKRNFHLVDSSPCQEIMQSK---------KNCTEYEANKERQGCRANQSTGLTTEVQNLKLSGCESQQLDYANKENIVTYLTDR-QTPEKLHIPTIAKNLMSELDEDCELSSKKDC----LSSNSVCSDEDR-ALKTTCVDSDSSFPGVSMMESSLEIQALEPDKSIRDYSFEEPNTED----------LFVLPKCQENSLPQDDCHACIQDSSQ-VSAHPSKAPKALTSKINVVAFRSFNSHINASTNSEPSKISITSLDAMDISCDYSGSYPMAVSPTEKGRH--YTSH-QTPNQVKLG-TSYRTPKSVRRGAAPVDDGRILGTPDYLAPELLLGTAHGPAVDWWALGVCLFEFLTGIPPFNDETPQQVFQNILKRDIPWPEGEE------KLSDNAQSAMDMLLTIDDSKRAGMRELKQHPLFSEVDWENLQHQTMPFVPQPDDETDTSYFEARNNAQHLTISGFSL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A355-1", "uniprot_id": "D4A355_RAT", "id": "D4A355-1", "name": "Serine/threonine-protein kinase greatwall", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MESASGSE-ENEEGAATEK----------CVNRIPVPRPPSIEEFTIVKPISRGAFGKVYLGQK--GSKLYAVKVVKKADMINKNMTHQVQAERDALALSKS-PFVVHLYYSLQSASNVYLIMEYLIGGDVKSLLHIYGYFDEEMAIKYTSEVALALDYLHRHGIIHRDLKPDNMLISNEGHIKLTDFGLSKVTLNR-------------------------------DINMMDILTTPSMSKPKQDYSRTPGQVLSLISSLGFFTPVGEKDQDSAN------VFSAPKSE---AQLSQGSICPMSIDQKEP--------VSYSSKLLKSCFETLASNPEIPVKCLTSNLLQCRKRLGTSST-SSQSHTFVSS----VESECHSSPKWEKDCQSAKPSS--TMMSWSAGEMPYAKSVSAIETK--------TDLELALSPIHDSS--------------------------------------------NIPPTGRNYMTLPRKCFSREISWEAREPDINNETMTID---EVSFCQSN----HWAVNSSATSEEHLC--KRNCKRNFHLVDSSPCQEIIQSK---------KNCIEYEANKEKTGCCANQATGLTAQVQNLKLSVCKSQQHDYANKENTVTYLTDR-RTPEELHIPTIAKNLMSELDEDCELSSKKDC----LHSNSVCSDEDR-APKTVCVDSDSSFPGVSMMESSLEIQALEPDKSIRDYSFEEPNTED----------LLMLPKCQENSLPKDDWHASIQDSNQ-MLAPPSKAPKTFASKTNVVAFRSFSSHINASSNSEPSKVSTTSLDTMDISCDYSGSCPMAVTPTEKGRA--CVSHQQTPSQVKLG-TSYRTPKSVRRGPPPVDDGRILGTPDYLAPELLLGAAHGPAVDWWALGVCLFEFLTGIPPFNDETPQQVFQNILKRDIPWPEGEE------KLSDKSQSAMDMLLTIDDTKRAGMKELKHHPLFSEVDWENLQHQTMPFVPQPDNETDTSYFEARNNAQHLTISGFSL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96GX5-1", "uniprot_id": "GWL_HUMAN", "id": "Q96GX5-1", "name": "Serine/threonine-protein kinase greatwall", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDPTAGSKKEPGGGAATEE----------GVNRIAVPKPPSIEEFSIVKPISRGAFGKVYLGQK--GGKLYAVKVVKKADMINKNMTHQVQAERDALALSKS-PFIVHLYYSLQSANNVYLVMEYLIGGDVKSLLHIYGYFDEEMAVKYISEVALALDYLHRHGIIHRDLKPDNMLISNEGHIKLTDFGLSKVTLNR-------------------------------DINMMDILTTPSMAKPRQDYSRTPGQVLSLISSLGFNTPIAEKNQDPAN------ILSACLSET--SQLSQGLVCPMSVDQKDT--------TPYSSKLLKSCLETVASNPGMPVKCLTSNLLQSRKRLATSSA-SSQSHTFISS----VESECHSSPKWEKDCQESDEALGPTMMSWNAVEKLCAKSANAIETKGFNK----KDLELALSPIHNSS--------------------------------------------ALPTTGRSCVNLAKKCFSGEVSWEAVELDVNNINMDTDTS-QLGFHQSN----QWAVDSGGISEEHLG--KRSLKRNFELVDSSPCKKIIQNK---------KTCVEYKHN-EMTNCYTNQNTGLTVEVQDLKLSVHKSQQNDCANKENIVNSFTDKQQTPEKLPIPMIAKNLMCELDEDCEKNSKRDY----LSSSFLCSDDDR-ASKNISMNSDSSFPGISIMESPLESQPLDSDRSIKESSFEESNIEDP---------LIVTPDCQEKTSPKGVENPAVQESNQKMLGPPLEVLKTLASKRNAVAFRSFNSHINASNNSEPSRMNMTSLDAMDISCAYSGSYPMAITPTQKRRS--CMPHQQTPNQIKSG-TPYRTPKSVRRGVAPVDDGRILGTPDYLAPELLLGRAHGPAVDWWALGVCLFEFLTGIPPFNDETPQQVFQNILKRDIPWPEGEE------KLSDNAQSAVEILLTIDDTKRAGMKELKRHPLFSDVDWENLQHQTMPFIPQPDDETDTSYFEARNTAQHLTVSGFSL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DBX4-1", "uniprot_id": "GWL_DANRE", "id": "Q6DBX4-1", "name": "Serine/threonine-protein kinase greatwall", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEAR---------GLACES----------SNS---AVKAPSIEDFVLVKPISRGAFGKVYLARKKCNSKLYAIKVVKKAEMVDKNMTEQMRAERDALALSKS-PFIVHLFYSLQTATKVYLVMEYLIGGDVKSLLHIYGYFDEDMSLKYISEVALALDYLHRHSIIHRDLKPDNMLISNEGHIKLTDFGLSKVKLDR-------------------------------ELNLMDILTTPSLVKPTKDYFRTPGQVLSLISSLGLNTPVIEGKRHSST------VLGSPMSCGKVKQRNRSLGSPLMKRRAEY--------MNSPVCTSRALASNSVFSPVLLARSLTPRLLKSGKRLDTMSVGSTHSCMLPST----TDSENCVSPMWEDEQNLHDVEN---------IPQLNGREVDNRKSR-----------NVPLTPVEKRK--------------------------------------------TLPARAQDHRPVFTPLNNQVTNSRNIKPDLSAKRLQFGAT-DNSATPLEKTVPHQSVGNGLIKPEPLKELKSSVKRAFEEVEKSPEQAEILFK---------KNDAAYERSFQIPEKTSRAHTGLTGIFSIVGLDDVKSAP--------KCQQFNER-TGPKQSSPIAVAKNLFCELEDQGEEGGKAEP----NSSSSTSPGDERNIRRSLSLESDVSAHEMSLVANTPQ-KLSDAKQEVLSSSFEELDENEISAVTPMARPTVATPKHSSAKQRRGECERSLLDHPHGLSDSMIKSPGFLKPK-NVVAFRSYCSSINRSCTS---HLSLASFDAMEMSASAS--FHNAVTPVQKKRPSLSNSLYQTPQQMVVSHTPYRTPKSVRRGPERVEGAPILGTPDYLAPELLLGKPHDFMVDWWALGVCLFEFLTGVPPFNDETPQLVFQNILNRDIPWPDGEE------ELTLNSRNAIEILLTMDTLKRAGLKELKDHPFFDGVDWENLHHQTMPFIPQPDNETDTSYFEARNTAQHLTVSGFSL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P43565-1", "uniprot_id": "RIM15_YEAST", "id": "P43565-1", "name": "Serine/threonine-protein kinase RIM15", "aln": "MFNRSNTAGGSQAMKEGLGINKLSPISSNSNPSSLTSSNYEKYLQLATEKNPCMILELELDGKVRYGSPQWNTITGVADDSGSSPTYIADLILGSDQDKGVFQKATDMLLMNDDTSCTITFKIKAADYEGSAGCDDESTITTLEARGILIRDGHTQLPSHTMWIVKPRTNDWSDFYANEDAQDDMVIQLSDNCDDIDIQLPEEFAKTLGFGAKIFVQYLKRIRLEMIIDEFNLPLPKMELCRVCENFVPVWWLETHSQSCVCEHRTESLIQLLHDNLLEQQAILANFTKDSEYKGSQIQVRSNNFLNQVLDSLRELCQDAIDINPSEMVPDLYHSLSTFPQDNGNNNNNNNNNNNNNNALLDQFPIQKDTVSLNSYFQFSPRTNHNIQNVTSWQSRFFLNDDQDPGLALLIHDTLDLARKKVDAVLRLDNAMTYSLKIKNEVNNYVVQLIREQIEINKHAILTHPMNLRSSSIFHSPLPQIHSQQPEAENLIYSSSTPLQVQHDQCASFEAPSKSHLEPIPFPVSSIEETPTANDIRHPSPLPRSCSNTVMKLPTPRRKLDSNGLFSDAYLNADIIPNPSIESTISIDRDNNTNSRGSSMKQYGIGEATDSRTSNSERPSSSSSRLGIRSRSITPRQKIEYSHVDNDDRTNEMLSRDKDSLQPQPSVDTTITSSTQATTTGTKTNSNNSTNSVLPKLMTSISLTPRRGSPSFGNLASHSMQQTNSFKLIHDKSPISSPFTFSKDFLTPEQHPSNIARTDSINNAMLTSPNMPLSPLLLATNQTVKSPTPSIKDYDILKPISKGAYGSVYLARKKLTGDYFAIKVLRKSDMIAKNQVTNVKSERAIMMVQSDKPYVARLFASFQNKDNLFLVMEYLPGGDLATLIKMMGYLPDQWAKQYLTEIVVGVNDMHQNGIIHHDLKPENLLIDNAGHVKLTDFGLSRAGLIRRHKFVPHKSSLSISSTLPIDNPANNFTMNNNNSNHSQLSTPDSFTSDHKQYNRSKKSSLGQQYEHSEYSSTSNSHSMTPTPSTNTVVYPSYYRGKDRSHGSSNIDLPASLRRSESQLSFSLLDISRSSTPPLANPTNSNANNIMRRKSLTENKSFSNDLLSSDAIAATNTNINSNNNISLSPAPSDLALFYPDDSKQNKKFFG--TPDYLAPETIEGKGEDNKQCDWWSVGCIFFELLLGYPPFHAETPDAVFKKILSGVIQWPEFKNEEEEREFLTPEAKDLIEKLLVVDPAKRLGAKGIQEIKDHPYFKNVDWDHVYDEEASFVPTIDNPEDTDYFDLRGAELQDFGDDIENDNANILFGKHGINTDVSELSAANLSPPLNHKNILSRKLSMSNTTNRSSNNSNSSVHDFGAHTPVNKLSIASVLESVPQETGYITPNGTGTTTTSAKNSPNLKNLSLAIPPHMRDRRSSKLNDSQTEFGSFNFRNLSALDKANKDAINRLKSEHFSEQPGVHRRTSSASLMGSSSDGSVSTPGSNASNTTSGGK-LKIHKPTISGSPSTFGTFPKTFLRSDSFSTRSYSPERSISIDSSTLSRKGSIIGDNQQTTANSSDSPTMTKFKSPLSPANTTTVSSYFSRQRVLSKSFSQRTNSSDLSAEESDRLQAISRVNSLRNRRRSGRKSSSTSEIGYHMDVLVCEPIPIHRYRVTKDLENLGCTVVSVGAGDELVSRATSGVSFDLIMTALKLPKLGAIDIVQLLKQTNGANSTTPIVAITNYFQEAATSRVFDDVLEKPVKLDELKKLVAKYALKKSQEDEEHTILSDSDETH--------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. . . . .***::: ::****:**:*.***.:* .. :*:**::*::*: ** . ::::** : :... *::.:*: *:*. :::*:**** ***: :*::: **: :: : :* :*:.:.:: :*::.***:****:*:**.* **:********:. * * : * :: *. *: . ::* *: . *. . . :. : . ... : : : . . * : : . : . . : :.** . . . * : : :::: .. : : : : . .: . : : .*.. . . . : . : . : . : .. . : * . : . :. : . : * .. . . . . .. : . .. *: : : .. ..: : . :: . : . : .. . ... .: . : : . . . . : . . . .: . : . : * * .. :.. . : : .:: . * : ..:: : * * . . * * *. * : : * ** :... :* .. *. *: *:. * : : :..: :: : :.*. .: . : . *. ::*:: . : : .:* : : : . * ", "identical_positions": 100, "similar_positions": 272, "identity": "5.61%" }, { "cls_id": "homologset.agr.RGD:1309187", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5PPK1-1", "uniprot_id": "BRI3_RAT", "id": "Q5PPK1-1", "name": "Membrane protein BRI3", "aln": "MDHKPLLQERPPAYNLEAGQGDYACGPHGYGAIPTAPPPPPYPYLVTGIPTSHPRVYNIHSRAVTRYPANSIVVVGGCPVCRVGVLEYCFTCLGIFLAIVLFPFGFLCCFALRKRRCPNCGAVFT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P28662-1", "uniprot_id": "BRI3_MOUSE", "id": "P28662-1", "name": "Membrane protein BRI3", "aln": "MDHKPLLQERPPAYNLEAGQGDYACGPHGYGAIPTAPPPPPYPYLVTGIPTSHPRVYNIHSRTVTRYPANSIVVVGGCPVCRVGVLEYCFTCLGIFLAIVLFPFGFLCCFALRKRRCPNCGAVFT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95415-1", "uniprot_id": "BRI3_HUMAN", "id": "O95415-1", "name": "Membrane protein BRI3", "aln": "MDHKPLLQERPPAYNLEAGQGDYACGPHGYGAIPAAPPPPPYPYLVTGIPTHHPRVYNIHSRTVTRYPANSIVVVGGCPVCRVGVLEDCFTFLGIFLAIILFPFGFICCFALRKRRCPNCGATFA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VZP9-1", "uniprot_id": "Q9VZP9_DROME", "id": "Q9VZP9-1", "name": "Membrane protein BRI3", "aln": "MADTRKDAAPPSYEEVMNSPSQDSRLIVGVHQGAPSAPPPNMHMPTYGAFETTPVSVVIQPAPVAMP--TEIIVIGGCPACRIGYLEDTFSACGLCCAIFFFPLGILCCLAMREKRCSNCGTVF-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* .. *. :: . .: : * ..:.*** . * * *:. .*: ..*:*:****.**:* ** *: *: **.:**:*::**:*:*::**.***:.* ", "identical_positions": 38, "similar_positions": 38, "identity": "30.4%" }, { "cls_id": "homologset.agr.RGD:1309188", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9BSF4-1", "uniprot_id": "TIM29_HUMAN", "id": "Q9BSF4-1", "name": "Mitochondrial import inner membrane translocase subunit Tim29", "aln": "MAAAALRRFWSRRRAEAGDAVVAKPGVWARLGSWARALLRDYAEACRDASAEARARPGRAAVYVG-------------------------------------LLGGAAACFTLAPSE--GAFEEALLEASGTLLLLAPATRNRESEAFVQRLLWLRGRGRLR-----YVNLGLCS-------------------------------------LVYEAPFDAQASLYQARCRYLQPRWTDFPGRVLDVGFVG----------RWWVLGAWMRDCDINDDEFLHLPAHLR-VVGPQQLHSETNERLFDEKYKPV--------------VLTDDQVDQALWEEQVLQKEKKDRLALSQAHSLVQAEAPR----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q4AE70-1", "uniprot_id": "CARM1_RAT", "id": "Q4AE70-1", "name": "Histone-arginine methyltransferase CARM1", "aln": "MAAAAATAVGPG-AGSAGVAGPGGAGPCATVSVFPGARLLTIGDANGEIQRHAEQQALRLEVRAGPDAAGIALYSHEDVCVFKCSVSRETECSRVGRQSFIITLGCNSVLIQFATPHDFCSFYNILKTCRGHTLERSVFSERTEESSAVQYFQFYGYLSQQQNMMQDYVRTGTYQRAILQNHTDFKDKIVLDVGCGSGILSFFAAQAGARKIYAVEASTMAQHAEVLVKSNNLTDRIVVIPGKVEEVSLPEQVDIIISEPMGYMLFNERMLESYLHAKKYLKPSGNMFPTIGDVHLAPFTDEQLYMEQFTKANFWYQPSFHGVDLSALRGAAVDEYFRQPVVDTFDIRILMAKSVKYTVNFLEAKEGDLHRIEIPFKFHMLHSGLVHGLAFWFDVAFIGSIMTVWLSTAPTEPLTHWYQVRCLFQSPLFAKAGDTLSGTCLLIANKRQSYDISIVAQVDQTGSKSSNLLDLKNPFFRYTGTTPSPPPGSHYTSPSENMWNTGSTYNLSSGVAVAGMPTAYDLSSVIAGGSSVGHNNLIPLANTGIVNHTHSRMGSIMSTGIVQGNRVAGPWAGDLPPGLRTRSSYQWGPGRLRGHAGSSVPMTCPTGSSGAQGGGGSSSAHYAVNNQFTMGGPAISMASPMSIPTNTMHYGS", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***** . . ..** * . .* * :. :. * * .:* : . .*. :. * * .* ** :. : :*... :* : * . * * : :.. *..: ** : : .: : **. * . . **. ** : .:.. * * . :**:* :*.: : ::. * :. :: .::*: ..:: .:* :* . *:*:*: *::. . .* . **: : : * : : :* * ::: ** . ", "identical_positions": 56, "similar_positions": 95, "identity": "8.59%" }, { "cls_id": "homologset.agr.RGD:1309189", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZJV4-1", "uniprot_id": "D3ZJV4_RAT", "id": "D3ZJV4-1", "name": "", "aln": "MAGRPEK-HLPLIRFTLLC------------------------------LKMVISSK---------------------------------------------------TAPEIPTIDQAYSKISNSITVEWTTVPGATSYLLTAE-DGDTTIETTVANSPGTVTGLKAATLYQITIRSVSASGRSPASPPKQAKTVLAAPILEVSSPSPDSILVSWDAVYMAIGFSVSVMQANGLGRIWKENTTNTSLTFSSLDAGTLYTIKAYAWNANGIPGDDSTRNQRTSPRAPANIQVFFDSG-ALKASVSWTPSEGAFNYTVVAWSGSSQRSCSTALSSCSIGSLQCGTEYLISVSANNDAGCSKSSSAPTLKTVACAPGRVMIQEEPPGHLSVAWSNVELGDYYVAFVKSDDGLEVHCNTSLTQCNFLSECGFTYFISVFAYNKAGQSPLGDVFNYTTAPCCPSDISPVLVSSDRVEIAWSPVRGAELYETKAIAGYSVVACNDTAPACTLSALDCDTKYNVTVYSFSEVRGSNLSCSSHFITTAPCSPEIKNISKDAFSMINVHWRSTNEGATYTVTAQGKKGLFRCSSTGETCRMGGLPCGSVFSVTAVAETQAGKSLPSYSVPLETVPCCPAGLTAAQVTQSIINVSWTIGAVAQTYVTVLESYIGQSKCHTHQNHCLLGCIACGINYTVALKAISPTGLTADCAYQSYSSSVCCPLGVKLYRLGPNGIRIYWQASRGSANYSTDLYGSKGIFTCAPHTGLSFCDITNIPCGDVYTVMVSPVAETGLKLTFCPKKIYSVTCSGSTLGMVIYRGKRNDTVSPR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2AED3-1", "uniprot_id": "FNDC7_MOUSE", "id": "A2AED3-1", "name": "Fibronectin type III domain-containing protein 7", "aln": "MAGRPEK-CFSLIRFTLLC------------------------------LKMVISSK---------------------------------------------------TAPEIPTIDQAYSKISNSITVEWTTVPGATSYLLTAE-DGNTIIETTVANSPGTVTGLKAATLYQITIRSISASGQSQASSPKQAKTVLAAPVLEVSSPSPDSILVSWDAVYMAIGFSVSVMRANGLGRIWKENTTNTSLTFSSLDAGTLYTIKAYAWNANGIPGDDSTRNQRTSPRAPANIQVFFDSG-ALKASVSWTPTEGAFNYTVVASSDSSQRSCSTTLSSCSISSLQCGTEYLISVSANNDAGSSKSCSAPTLKTVACAPGRVMIQEEPPGHLSVAWSNVELGDYYVAFVKSDDGLEVHCNTSLTQCNFLSECGFTYFISVFAYNKAGQSPLGDVFNYTTAPCCPNDISPVLVSSDRVEIAWSPVRGAELYETKAIAGYSIVECNDTAPACTLSALDCDTKYNVTVYSFSEVRGSNLSCSSHFITTAPCSPEIKNISKDAFSMINVHWRSTNEGATYTVTAQGKKGLFQCSSTGETCRMGGLPCGSMFSVTAVAETQAGKSLPSYSVPLETVPCCPAGLTAAQVTQSIINVSWTAGAVAQTYAAVLESYIGQSKCHTHQNHCLLGCITCGINYTVALKAISSTGLTADCAYQSYSSSVCCPLGVKLYRLGPNGIRIYWRASRGAANYSTDLYGSKGIFTCAPHAGLSFCDITNIPCGDVYTVMVSPVAETGLKLTFCPKKIYSVTCSGSTLGMVIYRGKRNDTASPR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5VTL7-1", "uniprot_id": "FNDC7_HUMAN", "id": "Q5VTL7-1", "name": "Fibronectin type III domain-containing protein 7", "aln": "MAGGRET-CLPLIGFILIC------------------------------LKMVASAK---------------------------------------------------SAPEIPTIDQAYSKLSNSITVEWATVPGATSYLLTAE-DGDTVIETTVANSPGTVTGLKAATWYEITIRSISAAGRSQASPPKQAKTVLAAPILEVSSPSSDSILVQWEAVYMAIAFSVSIMRANGLGSIWKENTTNTSLTFTSLEAGTLYTIKAYAWNANRIPGDDSTCNQRTSPRAPANIQVSFDSG-ALKASFSWARAEGAFNYTVMALSDSSELTCSTTFSSCTISSLQCGTEYLISVLASNDAGSSKSSSAMTLKTVACAPGRVTIQEDPPGHLSVAWSSVDLGDYYVVFVKSDDGLEVHCNTSLTQCNFLSECGFTYFISVFVYNKAGQSPLGDIFNYTTAPCCPSDINPVLVSSDRVEIVWSPVRGAELYETKAVDGYNMVECNDTTPACTLSALECDTKYNITVYSFNEVRGSNMSCTPQFITTAPCSPEIKNVSRDAFSMINVHWRSTNDDATYTVTAQGEKGLYQCSSTGESCTMRGLPCGSVFSVTAVAETQAGRSLPSYSVPLETVPCCPTGLTVTQITQSVINVSWTIGRVAQTHVAVLESHTGQSKCHTHQNHCLLGCITCGINYTVTLKAISATGLTADCSYQSYFSGACCPLGVKLYRLGPNGIRIYWQASRGSANYSTDLYGSKGIFTCTPSAGLSFCDVTEIPCGDVYTVMVSPVAKTGLKLTFCPKKIYSVTCSGSTLGMVIYRGKRNEE----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1REU3-1", "uniprot_id": "A0A8M1REU3_DANRE", "id": "A0A8M1REU3-1", "name": "", "aln": "MESRHLSNILLIITLSQICTAQNDITLSVFTVTSKSMTVRWSGHTGASSYKITATPKNSPEPSVFAQFSGSTVMGSVNSLSPNTVYRMRVEAMDNAVNVLSSAETEEMTAPEVPLIEKAYSKRSDSITVEFGIVSGATGYIIRAENDNGFFSETPVLKSPETVVGLDPYTDYTLSVMSVNVGGRSQPSLPVDAKTVLVAPNLRSSSPSSDSIMITWDPVNNAVLYTL-VMIMEGSDTRDKLNTSGTNMTYSGLQPGTTYCIKGNAWDPEGNQGDDITICQITRPPVPGDVQVQLTPGRSIDLAVYWQSVRGADGYIAVSSTG--QNCSSNEEVYCIISPLSCSQNHSITVVAQNAAGYSDPSQPQDLLTFPCPPDVVWIKEVTPGNCSVMWSDIPWVDYCIAYVKRDDGLEENCNTTGRSCHFQCKCGYTYLSTVFAYNQAGSSPPGQIVNYTTIPCCPEDVSVSLISTETLEISWSAVRGAELYETIAADGSEQIHCNDTAPVCALSDLTCDSMYSVVVRPCSEIRGCNNTCPAHTRQTAPCAPVILSVTQVNSSTVQVFWTPTNTQANYSIIAEGQTDSLSCSSSGTSCYMS-VTCGSMYEVSAYATTTAGLSLPSYAVPLETGPCCPEYLNVEQVTQSMTNVTWSPAIGARSYITSLTSPRGHAKCHTMDTDCLLGCITCGTSYNVSLEAFSITGHKTECTYQGFSASSCCPSSVKLYRMPNSTLRVNWRYSPGLYNYTADLYGTRSNYTCSSTAGANTCDVSEILCGEVYTVVVAPLTKDGTKVTFCPRKLYSVSCSGNTVGMVIYRGRRSVG----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 320, "similar_positions": 238, "identity": "38.98%" }, { "cls_id": "homologset.agr.RGD:1309190", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "F1M9U4-1", "uniprot_id": "F1M9U4_RAT", "id": "F1M9U4-1", "name": "MutS protein homolog 4", "aln": "MCSLRLRLRDGSTAHAPSLPPFQWHGFRPWGTRGLTRRASSVRKAREMLRQEATSLSSSPRWTPSRREVPRRRTPASASRPSTEGAVADRSSSSSSSS-PAPAA--APGSSFGNKRSYTTHKAASNFPVGTSSSSAQDTTYPHTFRTPLSAGNPQRS-YKGWTPQVGLSATSS-AVSAHAPSVIVAVVEGRGLARGEIGMASIDLKSPQIMLSQFADNTTYAKVITKLQVLSPLEIIMSNTACVVGNSTKLFTLITENFKNVNFTTVQRKYFNETKGLEYIEQLCIAEFSS--VLMEVQSRYYCLAAAAALLKYVEFIQN----SVYAPKSLKIYFQGSEQTAMIDSSSAQNLELLVNNQDYRSNHTLFGVLNYTKTAGGSRRLRSNILEPLVDVETISMRLDCVQELLQDEELFYGLQSVISRFLDTEQLLSVLVQIPKQDTVNAAESKITNLIYLKHTLELVDPLKVALKN--CSTPLLRAYYGSLEDHRFGLILEKIKTVINDDARYMKGCLNMRTQKCYAVRSNISEFLDIARRTYTEIVDDIAGMISQLAEKYSLPLRTSFSSARGFFIQMTTDCAALSSDQLPSEFIKISKVKNSYSFTSADLIKMNERCQESLREIYHMTYMIVCKLLSEIYEHIHCLYKLSDTVSMLDMLLSFAHACTLSDYVRPEFTDTLAIKQGWHPILEKISAEKPVANNTYITEGSNVLIITGPNMSGKSTFLKQIALCQIMAQIGSFVPAQYASFRIAAQIFTRISTDDDIETNSSTFMKEMKEIAYILHNANDKSLILIDELGRGTNTEEGTGISYAVCEHLLSTKAFTLFTTHFLELCHIDTLYLNVENMHFEVQHVKNTSRNKDAILYTYKLSRGLTEEKHYGLKAAEASSLPPSIVLDAREITTQITRQISQNRRSSPEMDRQRAVYHLATRLVQVARNSQLEPDRLRTYLSNLKKKYEGDFPRAADLPEKTEE---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99MT2-1", "uniprot_id": "MSH4_MOUSE", "id": "Q99MT2-1", "name": "MutS protein homolog 4", "aln": "MCCLFLRLRDYSTAHALSLPPCQRCGLQPWSARSHARRTLGVRKAGEMLRQEAASLSSSPRWTPSRRDAPCGRTLASASRPSTEGAMADRSSSSSSS--PAPAS--APGSSFGNKRSYAIHRAASSFPVGTSSSSARDTTYPHTFRTPLSAGNPQRSGHKSWTPQVGYSATSS-AVSAHAPSVIVAVVEGRGLARGEIGMASIDLKSPQIMLSQFADNTTYAKVITKLQVLSPLEIIMSNTACVVGNSTKLFTLITENFKNVNFTTVQRKYFNETKGLEYIEQLCIAEFSS--VLMEVQSRYYCLAAAAALLKYVEFIQN----SVYAPKSLKIYFQGSEQTAMIDSSSAQNLELLVNNQDYRSNHTLFGVLNYTKTAGGSRRLRSNILEPLVDVETISMRLDCVQELLQDEELFFGLQSVISRFLDTEQLLSVLVQIPKQDTVNAAESKITNLIYLKHTLELVEPLKVTLKN--CSTPLLRAYYGSLEDHRFGLILDKIKTVINDDARYMKGCLNMRTQKCYAVRSNISEFLDIARRTYTEIVDDIAGMIAQLAEKYSLPLRTSFSSSRGFFIQMTTDCAALSSDQLPSEFIKISKVKNSYSFTSADLIKMNERCQESLREIYHMTYMIVCKLLSEIYEHIHCLYKLSDTVSMLDMLLSFAHACTLSDYVRPEFTDTLAIKQGWHPILEKISAEKPVANNTYITEGSNVLIITGPNMSGKSTYLKQIALCQIMAQIGSYVPAEYASFRIAAQIFTRISTDDDIETNSSTFMKEMKEIAYILHNANDKSLILIDELGRGTNTEEGIGISYAVCEHLLSIKAFTLFTTHFLELCHLDALYLNVENMHFEVQHVKNTSRNKDAILYTYKLSRGLTEEKNYGLKAAEASSLPSSIVLDARDITTQITRQILQNQRSSPEMDRQRAVYHLATRLVQAARNSQLEPDRLRTYLSNLKKKYAGDFPRAVGLPEKTEE---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15457-1", "uniprot_id": "MSH4_HUMAN", "id": "O15457-1", "name": "MutS protein homolog 4", "aln": "------MLRPEISSTSPSAPAVS-------PSSGETRSPQGPRYN--------FGLQETPQSRPS------VQVVSASTCPGTSGAAGDRSSSSSSLPCPAPNSRPAQGSYFGNKRAYAENTVASNFTFGASSSSARDTNYPQTLKTPLSTGNPQRSGYKSWTPQVGYSASSSSAISAHSPSVIVAVVEGRGLARGEIGMASIDLKNPQIILSQFADNTTYAKVITKLKILSPLEIIMSNTACAVGNSTKLFTLITENFKNVNFTTIQRKYFNETKGLEYIEQLCIAEFST--VLMEVQSKYYCLAAVAALLKYVEFIQN----SVYAPKSLKICFQGSEQTAMIDSSSAQNLELLINNQDYRNNHTLFGVLNYTKTPGGSRRLRSNILEPLVDIETINMRLDCVQELLQDEELFFGLQSVISRFLDTEQLLSVLVQIPKQDTVNAAESKITNLIYLKHTLELVDPLKIAMKN--CNTPLLRAYYGSLEDKRFGIILEKIKTVINDDARYMKGCLNMRTQKCYAVRSNINEFLDIARRTYTEIVDDIAGMISQLGEKYSLPLRTSFSSARGFFIQMTTDCIALPSDQLPSEFIKISKVKNSYSFTSADLIKMNERCQESLREIYHMTYMIVCKLLSEIYEHIHCLYKLSDTVSMLDMLLSFAHACTLSDYVRPEFTDTLAIKQGWHPILEKISAEKPIANNTYVTEGSNFLIITGPNMSGKSTYLKQIALCQIMAQIGSYVPAEYSSFRIAKQIFTRISTDDDIETNSSTFMKEMKEIAYILHNANDKSLILIDELGRGTNTEEGIGICYAVCEYLLSLKAFTLFATHFLELCHIDALYPNVENMHFEVQHVKNTSRNKEAILYTYKLSKGLTEEKNYGLKAAEVSSLPPSIVLDAKEITTQITRQILQNQRSTPEMERQRAVYHLATRLVQTARNSQLDPDSLRIYLSNLKKKYKEDFPRTEQVPEKTEE---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32T720-1", "uniprot_id": "A0AB32T720_DANRE", "id": "A0AB32T720-1", "name": "", "aln": "---MFCSSTEEVTAGSSSEPERS----------SSTLTPYNLMNY--------SQIFGRQQDPPS-------SSVLLTSRESDD-VRISVCPGSSSDTLPSALSETTPTAAQGHLN--ISETAYRTNSSGGSSAHSWTSSTPQLKTTPALS-HHSRTPRRDLNMTTSSSASAS--HAARAP-VIVAVVEGRGLARGEIGMASINMKYPELVLSQFVDTGTYTKVITKLHNLTPMEILMPDTASVKGQGTKLYSLITETFPSVTFTAVLRRYFNEKKGLEFIQQLCVPEFTT--VLMEVQTKYYCLASASALLKYFEFVQK----SIYAPKSLKVTFSGSEQTAMIDAVSASNLELVVNHRNHRSEHTLFGVLNHTKTSGGERRLRSNILEPLLEVDTIKSRQDTIQELLQNEELFFSLKNAIAHFLDIDELLSALVQIPKQETIAVAEAKITQVIQLKHIVELVPSLKVMLQH--STTHLLTAYCKSLEDCRFNSILDHIKSLINDDTSYMKGSLTMRTQKCYAVRPNVSEFLDIARRAYTEVVDDIAGLVAQLGEKHNLPLRTSFSNARGFFIQMKLEGGALPGGKLPDEFIKVSKQKNNFSFTTLDLMKMNDHCEEALKDIFHMSYVVVSKLLNEVHEQIHCLYKLSDVVSMLDMLLSLANACTISNYVRPEFTDTLAIQQGRHPVLERISGQQPISNNSYISEGSNFVIITGPNMSGKSTFLKQVALVQIMAQIGCFVPAEYASVRIADQIFTRIGVDDDFETNSSTFMVEMKEVSYIIHNATNSSLIIIDELGRGTSPEEGIGICHSVCEFLINLKAFTLFATHFLELCQLQTLYPNVENQHMQVQHIRTGDGRAERVVYTYQLSRGHSEERNYGIRAAEMTNLPLDIIQEAKTVADKINQKLWAKHHSDPATLKQRADYRLATRLVQTARNSQLDRASLRHYLKGLKTQYLAEIQMIKENATELVEIEE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P40965-1", "uniprot_id": "MSH4_YEAST", "id": "P40965-1", "name": "MutS protein homolog 4", "aln": "----------------------------------------------------------------------MSESNLSSFISTNYFNLRSAANSSNSISKPSTKKSIRNQKSPTNISSWALKKKTLQIAETTWENNEKDSTHSHYLMTGSMASRTATSLSRYSTNASLLGPSID--------CVLCCIYEVPRDISTRIGLCIINCNTGQMYLSDFMDSQIYIRVVHKLQIYQPTEILIPSSSLAPTVSKLATMIKFNVAETVKIEEGSRKCFNSQDGLAAITKYLMDDTKKDLKIEEIIDKTFALCAASAAISYMEEIISKSSRNLNAFRKLRIQFEGTENTMLIDSKTVRGLELVENKLDK-NGISLWKFLDTTSTKMGQRSLRNSILQPLTDRGSIEMRLEALEELKANDDLLQKLRLEMKSLPDLDKLFSRLLCIN--HSAIKPDQRINYVLLLKETLQSVKSLKDALNDQLIQSRLISETKKIFNNDAIMEIEKLINSCINEDCVWASSAIQLLNQRSYAVKSDSNGLLDVSRQIYKEVKEEFFREVEDLTAKNKINLDHNYDSARGFYLRIKRQEFTDDVATLPDVFISRTIKKNYIECTTLNIIKKNARLKEVMEEILLLSEETVDELLDKIATHISELFMIAEAVAILDLVCSFTYNLKENNYTIPIFTNNLLIRDSRHPLLEKVLKNFVPNTISSTKHSSSLQIITGCNMSGKSVYLKQVALICIMAQMGSGIPALYGSFPVFKRLHARVCN-DSMELTSSNFGFEMKEMAYFLDDINTETLLILDELGRGSSIADGFCVSLAVTEHLLRTEATVFLSTHFQDIPKIMSKKPAVSHLHMDAVLLNDNS-----VKMNYQLTQKSVAIENSGIRVVKKIFNPDIIAEAYNIHSLLKIAKARTENEDSNGVVDQKTINQMKRIHNLVAILKECAGNEKEPLTLGKLKEINSDFIENFEE---------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . .*.* *:. : . . . :. .: * : . : : . ..: . *: .: * .**:. *: : :: **:* *. * :*: **: * **::..:: . .. : : .*.: *: **. .** * : : : .. : *: : :.*.:.:* :.*.* : . .: * :.*:: *.*:*:* :**: :. .***: *: : . :*: .*: *.* *.* **..**:** : :*. * : ::** :::*: *: : : * ::*:* *: * .: .: :*. :: **. :: * .** ::. : *: ::: : * . *:: **:* : ...: : .*:.***:.: . :**::*: *.*: ::: : :* * .: * .:..:***::::. : : **. **. : ** . *: :::* * : :* :.:* :: * :**.:: :* *: :::.*::**:: *:: . .:*. * **:.* *::. **:**:: : . : ...*.. **** ******.:***:** ****:*. :** *.*. : ::.:*: *.:* .**.* ****::*::.: . .:*:::******:. :* :. :* *.*: :* .:::*** :: :: : *.: *::. :. . : .*:*:: .: *::..: * * . : : :... *:: :: .* .: . . .: :: ", "identical_positions": 184, "similar_positions": 321, "identity": "18.89%" }, { "cls_id": "homologset.agr.RGD:1309191", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZSY8-1", "uniprot_id": "D3ZSY8_RAT", "id": "D3ZSY8-1", "name": "", "aln": "METGPAPLVAPPRRHGASAAPSPPPRGSRAGSVLVVAPGPPVTTATSAPVDLVVPGEARPAWVPGSLQTSASTPTTA-------TGS-TVELTLEASPEAAKT-----QEFPAPAAEAGAETSVALVLGTDTPKTEEARASPVPGP----GTPTRTPSRTASGALTAKPPLAPKPGTTVASGVTARGGAGQVAGGH--GAATSASAGPVPEDPSGPVTGPPGTCEASAP--VARVTVTPAPETTENFQDLGSTSSLGPGISGPRGQAPDTLSYLDSVSLMSGTLESLTDDVSSVGSDSEINGLALRKTDKYGFLGGSQYSGSLESS----IPVDVARQRELKWLEMFSN--------WDKWLSRRFQKVKLRCRKGIPSSLRAKAWQYLSNSKELLEQNPGKFEELERAPGDPK----------WLDVIEKDLHRQFPFHEMFAARGGHGQ-----QDLYRILKAYTIYRPDEGYCQAQAPVAAVLLMHMPAEQAFWCLVQICDKYLPGYYSAGLEAIQLDGEIFFALLRRASPLAHRHLR---------RQRIDP---------------------VLYMTEWFMCIFARTLPWASVLRVWDMFFCEGVKIIFRVALVLLRHTLGSVEKLRSCQG--MYETMEQLRNLPQQCMQEDFLVHEVTTLPVTEALIERENAAQLKKWRETRGELQYRPSRRLHGSRAIHEERRRQQPPLGPSSSLLSLPSLKSRGSRAVGGAPSPPPPVRRASAGPVPGAVVIAEGLHPSLPSPTGNSTPLGTSKEIRRQEKERQKQEKEREKERQRQEKEREKQEKERQKWEKEQEKEQQKQEKERQKLEKKGQGRKLSLRRKADGPPAPQDGGDRSAAEARQDAYF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BHL3-1", "uniprot_id": "TB10B_MOUSE", "id": "Q8BHL3-1", "name": "TBC1 domain family member 10B", "aln": "METGPAPLVAPPRRHGAPAAPSPPPRGSRAGSHLVVEPGPPVTTATSAPVELVAPGEARPACVPGSSQTSASTPTTA-------TSSTVVMLTLEASPEAAKT-----QEFPAPAAETGAETSVALALGTDTQKTEEVRASPVPGP----GTPTRTPSRMAPGALTAKPPLAPKPGTTVASGVTARGGVGQVAGGH--EAATSASAGSVPEDPSGPVTGPPGTCEAPAPTPVAVVTVTPAPEPVENFQDLGSTSSLGPGISGPRGQAPDTLSYLDSVSLMSGTLESLPDDVSSMGSDSEINGMALRKTDKYGFLGGSQYSGSLESS----IPVDVARQRELKWLEMFSN--------WDKWLSRRFQKVKLRCRKGIPSSLRAKAWQYLSNSKELLEQNPGKFEELERAAGDPK----------WLDVIEKDLHRQFPFHEMFAARGGHGQ-----QDLYRILKAYTIYRPDEGYCQAQAPVAAVLLMHMPAEQAFWCLVQICDKYLPGYYSAGLEAIQLDGEIFFALLRRVSPLAHRHLR---------RQRIDP---------------------VLYMTEWFMCIFARTLPWASVLRVWDMFFCEGVKIIFRVALVLLRHTLGSVEKLRSCQG--MYETMEQLRNLPQQCMQEDFLVHEVTNLPVTEAWIERENAAQLKKWRETRGELQYRPSRRLHGSRAIHEERRRQQPPLGPSSSLLSLPSLKSRGSRAVGGAPSPPPPVRRASAGPVPGAVVIAEGLHPSLPSPTGNSTPLGTSKEIRRQEKERQKQEKDREKERQRQEKERERQEKERQKWEKEQEKEQQKQEKERQKLEKKGQGRKLSLRRRADGPPASHDGGDRSAAEARQDAYF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4KMP7-1", "uniprot_id": "TB10B_HUMAN", "id": "Q4KMP7-1", "name": "TBC1 domain family member 10B", "aln": "METGTAPLVAPPRRHGAPAAPSPPPRGSRAGPVVVVAPGPPVTTATSAPVTLVAPGEARPAWVPGSAETSAPAPAPAPAPAPAVTGSTVVVLTLEASPEAPKPQLPSGPESPEPAAVAGVETSRALAAGADSPKTEEARPSPAPGPGTPTGTPTRTPSRTAPGALTAKPPLAPKPGTTVASGVTARSASGQVTGGHGAAAATSASAGQAPEDPSGPGTGPSGTCEAPVA----VVTVTPAPEPAENSQDLGSTSSLGPGISGPRGQAPDTLSYLDSVSLMSGTLESLADDVSSMGSDSEINGLALRKTDKYGFLGGSQYSGSLESS----IPVDVARQRELKWLDMFSN--------WDKWLSRRFQKVKLRCRKGIPSSLRAKAWQYLSNSKELLEQNPGKFEELERAPGDPK----------WLDVIEKDLHRQFPFHEMFAARGGHGQ-----QDLYRILKAYTIYRPDEGYCQAQAPVAAVLLMHMPAEQAFWCLVQICDKYLPGYYSAGLEAIQLDGEIFFALLRRASPLAHRHLR---------RQRIDP---------------------VLYMTEWFMCIFARTLPWASVLRVWDMFFCEGVKIIFRVALVLLRHTLGSVEKLRSCQG--MYETMEQLRNLPQQCMQEDFLVHEVTNLPVTEALIERENAAQLKKWRETRGELQYRPSRRLHGSRAIHEERRRQQPPLGPSSSLLSLPGLKSRGSRAAGGAPSPPPPVRRASAGPAPGPVVTAEGLHPSLPSPTGNSTPLGSSKETRKQEKERQKQEKERQKQEKEREKERQKQEKERE----KQEKEREKQEKERQKQEKKAQGRKLSLRRKADGPPGPHDGGDRPSAEARQDAYF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VGL8-1", "uniprot_id": "TBWKD_DROME", "id": "Q9VGL8-1", "name": "TBC1 domain family member whacked", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATAPRS--------LDTISLCS--------TVSSCP-------------DRNGFYGGFQRTDKPKEP----LSKAQIIAREKKWLYMIDN--------WSIYMSKNYKKIRDRCRKGIPKSVRPKAWFYLSGAYLLKKKNPNVYNELLEKPGNPT----------TIEEIKKDKHRQFPFHEMFLDEQKVGQ-----IELFNVLKAYSIYNPKVGFCQAQAPIAAFLLMHLPAEDAFWVFVSVCDVYLQDYFIPGLEVIQNDAGILEGLLKKTCPPVYRHLQ---------KHKVEP---------------------LLYMTDWFLCAMTRTLPWETLLRVWDCFLAEGIRVIFKVALVIIGASLSRHKVRKTCTG--LCETLAVLRSPEEHIVEEEFIINNMMRLNLRVEDFQIEHTRQKARRAKQKAQQEAESSGSGNG-------HRRNMPTL---------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P48566-1", "uniprot_id": "GYP3_YEAST", "id": "P48566-1", "name": "GTPase-activating protein GYP3", "aln": "-------------------------------------------------------------------------------------------------------------------------------MQNDQQRFSLQN-----------RTVLAHPYKRLGGAFTVKSPSVPNFHDKMHSDHSS-SDSALVNGSFRANDHRSVEPSCLGQASPSEHDGN-------------LSVIDLYGDEVESQRAEGEDDDDNNGDNGNEDLEEVHSDDLDLVPDDDNRQRVELEGAASATSANS-NGINNTHFDRYGFKKQNNYISEAEYDKWWVEYSQYCVRRKHKWQLLLEKSGLPVTDDSPSRFPSKSERLKRYVRKGIPAEWRGNAWWHFARGQEKLNKNKGVYSQLLRKMKQIKKQNPNEKQVQDLDIIERDLNRTFPDNIHFQSSLHNKEGPPIIKSLRRVLVAFSLYNPKIGYCQSMNFLAGLLLLFLDEERAFWMLVIITSRYLPGVHNINLEGVNIDQGVLMLCVKEYIPEVWSYIKPSIDHHQKNNKTFSPSNKKVLFNMQKNEFLYRLPPITLCTASWFMSCFVGVVPIETTLRIWDCLFYEESHFLFKVSLAVLKLSEHDLSKIKPRNNSLNYSWGSNLNQRGGSMGQEDSDMEIFQVIQTFPKTLLNPNEIFEKIIFKRRFNLNRLDQDEIDRCRKFVAAQRLKFKTYG-----------------ELLGNSTSEADLPINDNTDNKGIHITSDAVNEALSSEVYGFKKSLAGVHWNNSIKEKVKQMRKKKDKGD------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. .. ** :. . .:* *: ** : .. : *: ** ::.: :. . :::: ***** . * :** ::: . ::* . :.:* . : . :: *::* :* ** : * : .* .:* *:::*.*. *:**: :*..**:.: * *** :* : . ** . . .** :: * :: ::. * . ::: .: ..* * :.**:. :. .:* : **:** :: * :.:*:*:*.:: : . :. . . *.. :*: :. . : : : : : : : . . :* : . ", "identical_positions": 63, "similar_positions": 130, "identity": "7.2%" }, { "cls_id": "homologset.agr.RGD:1309192", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A6N3IN21-1", "uniprot_id": "SDSL_RAT", "id": "A0A6N3IN21-1", "name": "Serine dehydratase-like", "aln": "MEGASAECVRAEPFHRVTPLLESWALSQVAGMPVFLKYENVQIAGSFKIRGIGHFCQQMAKRG------CRHLVCSSGGNAGIAAAYSAQKLGIPVTIVLPESTSKQVVRRLEGEGAEVQLTGKVWDEAN--VRAQELATRD----GWVNVSPFDHPLIWEGNASLVRELKESLR------TPPGAVVLAVGGGGLLAGVVAGLLEVGWQH-VPIVAMETRGAHSFNAALLAGRLVTLPDITSVARSLGAKTVAARTLECAKECEVLSEVVEDREAVRAVQRFLDDERMLVEPACGAALAAVYSGILGRLQTEGRLSPALDSVVVIVCGGNNISSQQLQELKTQLNCS------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R238-1", "uniprot_id": "SDSL_MOUSE", "id": "Q8R238-1", "name": "Serine dehydratase-like", "aln": "MEGALAERVGAEPFHRVTPLLESWALSQVAGMPVFLKYENVQIAGSFKIRGIGHFCQQMAKRG------CRHLVCSSGGNAGIAAAYSARKLGIPVTIVLPEGTSVQVVRRLEGEGAEVQLTGKVWDEAN--VKAQELATRD----GWVNVSPFDHPLIWEGHASLVRELKESLG------TPPGAVVLAVGGGGLLAGVTAGLLEVGWQH-VPIVAMETRGAHSFNSALQAGRPVTLPDITSVAKSLGAKTVAARTLECAKECEVLSEVVEDREAVSAVQRFLDDERMLVEPACGAALAAIYSGILWRLQAEGRLSSALASVVVIVCGGNNISSQQLQELKIQLGCS------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96GA7-1", "uniprot_id": "SDSL_HUMAN", "id": "Q96GA7-1", "name": "Serine dehydratase-like", "aln": "MDGPVAEHAKQEPFHVVTPLLESWALSQVAGMPVFLKCENVQPSGSFKIRGIGHFCQEMAKKG------CRHLVCSSGGNAGIAAAYAARKLGIPATIVLPESTSLQVVQRLQGEGAEVQLTGKVWDEAN--LRAQELAKRD----GWENVPPFDHPLIWKGHASLVQELKAVLR------TPPGALVLAVGGGGLLAGVVAGLLEVGWQH-VPIIAMETHGAHCFNAAITAGKLVTLPDITSVAKSLGAKTVAARALECMQVCKIHSEVVEDTEAVSAVQQLLDDERMLVEPACGAALAAIYSGLLRRLQAEGCLPPSLTSVVVIVCGGNNINSRELQALKTHLGQV------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PEB6-1", "uniprot_id": "A0A8M9PEB6_DANRE", "id": "A0A8M9PEB6-1", "name": "L-serine ammonia-lyase", "aln": "MS-------KQNGFHVVTPLLESTGMSKLVGSTVYLKMESSQPAGSFKIRGIGYMCQNVASSNK-----SRGVICSSGGNAGMATAYAARKLNLPATIVLPLSTPELVAQKLKDQGATVKAVGKVWDDAN--AEALRLAESE----GLTVIHPFNQPLVWKGHSSIVHELKASLP------SRPGLIVLSVGGGGLFCGVIEGLDEVGWGD-VPVLCMETKGADCFNVALKAKNLVTLPDITSQAVCLGAKTACQQAFEYGKRPTVISEVVTDLQALEAVELFLDEERVLVELACGASLAAVYSGVVNRLQDEGRLPKPLGPLVMIVCGGGSMNMAQLQHLQAVIRK-------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P25379-1", "uniprot_id": "STDH_YEAST", "id": "P25379-1", "name": "Catabolic L-serine/threonine dehydratase", "aln": "----------MSIVYNKTPLLRQFFPGKAS-AQFFLKYECLQPSGSFKSRGIGNLIMKSAIRIQKDGKRSPQVFASSGGNAGFAAATACQRLSLPCTVVVPTATKKRMVDKIRNTGAQVIVSGAYWKEADTFLKTNVMNKIDSQVIEPIYVHPFDNPDIWEGHSSMIDEIVQDLKSQHISVNKVKGIVCSVGGGGLYNGIIQGLERYGLADRIPIVGVETNGCHVFNTSLKIGQPVQFKKITSIATSLGTAVISNQTFEYARKYNTRSVVIEDKDVIETCLKYTHQFNMVIEPACGAALHLGYNTKILEN-ALGSKLAADDIVIIIACGGSSNTIKDLEEALDSMRKKDTPVIEVADNFIFPEKNIVNLKSA", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .: ****.. .: .:** * * :**** **** : : * . :..*******:*:* :.::*.:* *:*:* .* :. ::.. ** * * *.:*: .: : : : **::* :*:*::*:: *: * . :* :****** *: ** . * . :*:: :**.*.. ** :: . * : .*** * .**: . . :::* : * *: * :.: : .: .:::* ****:* *. : . * . :::*.***.. . :*: : ", "identical_positions": 87, "similar_positions": 102, "identity": "23.39%" }, { "cls_id": "homologset.agr.RGD:1309193", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BGK6-1", "uniprot_id": "YLAT2_MOUSE", "id": "Q8BGK6-1", "name": "Y+L amino acid transporter 2", "aln": "-------------MEAQELGSPTPT---YHLLPKANQHTVKEDAGSPSQGSPE--TMQLK---KEISLLNGVSLVVGNMIGSGIFVSPKGVLKYTASYGLS-LIVWAIGGLFSVVGALCYAELGTTITKSGASYAYILEAFGGFIAFIRLWVSLLIVEPTSQAIIAITFANYIIKPSFPTCDPPYVACRLLAAACVCLLTFVNCAYVKWGTRVQDTFTYAKVLALIAIIIMGLVKLCQG-----HTEHFQDAFKGSSWNVGD--LSLALYSALFSYSGWDTLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNIQDVHKS-DAVAVTFADQTFG--MFSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPNLLSMIHIERFTPVPALLFN-----CTMTLIYLVVKDVFLLIN-YFSFSYWFFVGLSVVGQLYLRWKEP----DWPRPLKLSLFFPIVFCVCSLFLVAVPLFSDT------------INSLIGIGIALSGVPVYFLGVYLPESR--RPLFIRNVLATVTRVTQKLCFCVLTELDVTEEKNVERKTD--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZMM8-1", "uniprot_id": "YLAT2_RAT", "id": "D3ZMM8-1", "name": "Y+L amino acid transporter 2", "aln": "-------------MEARELGSPTPT---YHLLPKANQHTVKEDASSPSQGSPE--TMQLK---KEISLLNGVSLVVGNMIGSGIFVSPKGVLKYTASYGLS-LVVWAIGGLFSVVGALCYAELGTTITKSGASYAYILEAFGGFIAFIRLWVSLLIVEPTSQAIIAITFANYIIKPSFPTCDPPYVACRLLAAACVCLLTFVNCAYVKWGTRVQDTFTYAKVLALIAIIIMGLVKLCQG-----HTEHFQDAFKGSSWNVGD--LSLALYSALFSYSGWDTLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNIQDVHKS-DAVAVTFADQTFG--MFSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPNLLSMIHIERFTPVPALLFN-----CTMTLIYLVVKDVFLLIN-YFSFSYWFFVGLSVVGQLYLRWKEP----DWPRPLKLSLFFPIVFCICSLFLVAVPLFSDT------------INSLIGIGIALSGVPVYFMGVYLPEAR--RPLFIRKVLATVTRVTQKLCFCVLTELDVAEEKNVERKTD--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q92536-1", "uniprot_id": "YLAT2_HUMAN", "id": "Q92536-1", "name": "Y+L amino acid transporter 2", "aln": "-------------MEAREPGRPTPT---YHLVPNTSQSQVEEDVSSPPQRSSE--TMQLK---KEISLLNGVSLVVGNMIGSGIFVSPKGVLVHTASYGMS-LIVWAIGGLFSVVGALCYAELGTTITKSGASYAYILEAFGGFIAFIRLWVSLLVVEPTGQAIIAITFANYIIQPSFPSCDPPYLACRLLAAACICLLTFVNCAYVKWGTRVQDTFTYAKVVALIAIIVMGLVKLCQG-----HSEHFQDAFEGSSWDMGN--LSLALYSALFSYSGWDTLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLSS-DAVAVTFADQTFG--MFSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIHIERFTPIPALLFN-----CTMALIYLIVEDVFQLIN-YFSFSYWFFVGLSVVGQLYLRWKEP----KRPRPLKLSVFFPIVFCICSVFLVIVPLFTDT------------INSLIGIGIALSGVPFYFMGVYLPESR--RPLFIRNVLAAITRGTQQLCFCVLTELDVAEEKKDERKTD--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q59I64-1", "uniprot_id": "YLAT2_DANRE", "id": "Q59I64-1", "name": "Y+L amino acid transporter 2", "aln": "--------------------------------------------------------MQLK---KEISLLNGVSLIVGNMIGSGIFVSPKGVLIYSASYGLS-LVIWAIGGIFSVVGALCYAELGTTITKSGASYAYILESFGGFIAFIRLWTSLLIIEPTSQAVIAITFANYLVQPLFPTCEPPYSASRLIAAACICLLTFINSAYVKWGTRVQDVFTYAKVLALIVIIITGIVKLCQG-----FTINFEDSFQGSSRDPGG--IALALYSALFSYSGWDTLNFVTEEIKNPERNLPLSIAISMPIVTIIYILTNVAYYAVLDMSAILAS-DAVAVTFADHTLG--VMSWTIPIAVALSCYGGLNSSIIAASRLFFVGAREGHLPDALSMIHIERFTPVPALLFN-----CAMALIYLTVEDVFQLIN-YYSFSYWFFVGLSIAGQIYLRWKEP----DRPRPLKLSLVYPIIFCLCVVFLVAVPLYSDT------------LNTLIGIAIALSGVPVYFLGIHLPESK--RPPIITKLLSAITRFTQFTCFYVLTEMDTVD-----------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KHK8-1", "uniprot_id": "A0A0B4KHK8_DROME", "id": "A0A0B4KHK8-1", "name": "Y+L amino acid transporter 2", "aln": "-------------METESLNRKNSSRK-SSIVNGNGDASAKLTNGDGDGGGDGGGEVTLK---AKMSLLNGCTVIVGSIIGSGIFVSPTGVLMYTGSVNLA-LIVWVISGLFSMVGAYCYAELGTMITKSGADYAYIMETFGPFMAFIRLWIECMIVRPCSQAIVALTFSTYVLKPFFPECTPPEDSARLLAVCCILVLTLINCWDVKWATAVQDIFTYAKLLALFIIIATGVYQLYLG-----NTQYFT--FENTDTKVTS--IALSFYSGLFAYNGWNYLNFIIEELKDPVKNLPRAIAISCTLVTIVYVMANVSFYTILSPDEVMGS-SAVAVTYAERAFG--MLAWTIPVFVALSTFGAVNGILLTSSRLFYAGANNGQMPEILTMIQIQRFTPTPAVLAM-----ALLSMLYLTVSDIFALIN-YVGFATWLSIGVAVLCLPWLRWAQP----NLPRPIRVPMVFPIVYLIATIFVTVVPMYASP------------VETGYGILMILSSIPVYLV--FIAWKN--KPIWFQKTMVSLTRFLQKMLMVLGKQTKPAQV----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P50276-1", "uniprot_id": "MUP1_YEAST", "id": "P50276-1", "name": "High-affinity methionine permease", "aln": "-----MSEGRTFLSQLNVFNKENYQFSSSTTKKEVSNSTVDADNGASDFEAGQQFATELDQGEKQLGILSCIGLICNRMLGTGVFAVSSTIYTLCGSVGLA-LIMWAVGAIIAISGLYVYMEFGTAIPKNGGEKNYLEAIFRKPKFFITCMYAAYIFFLGWAAGNSINTAIMFLTAADTEVTKWNQ--RGIGVAVVFFAFLINSLNVKIGLYLQNILGIFKIGIVLFISITGWVALGGGLKDGYQSHNFRNAFEGTETATAYG-IVNALYSVIWSFVGYSNVNYALGEVKNPVRTLKIAGPTSMVFLAIIYIFVNIAYFAVVPKDKLISSKLILAADFFDIVFGG-QAKRAAAALVGLSALGNVLSVIFSQGRIIQQLGREGVLPFSNFFASSKPFNSPMVGLFQH-FIVCTVTILAPPPGDAYLLVQNLISYPMNIINFAISAGLLWIYWQRRQGKIEWNPPIKAGVFVTGFFTLSNLYLIIAPYVPPSNGESVYSSMPYWIHCVIAWGIFFFGGVYYVVWAQLLPRWGHYKLVSKDVLGEDGFWRVKIAKVYDDTIGDVDTQEDGVIETNIIEHYKSEQEKSL", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P38734-1", "uniprot_id": "MUP3_YEAST", "id": "P38734-1", "name": "Low-affinity methionine permease", "aln": "MEPLLFNSGKANPSQDVFIDVEVGDITTKYGSTNTGSFSSMDTVEAQAIKAETARFMEVPQG-RHLGVFSTVVLFVSRIMGSGIFAVPSVILLNTGGNKLIYFAIWVFSAAIAFAGLYLFLEFGSWIPKSGGRKNFLERSFERPRLLISVVFSCYSVLTGYALTGSIVFGKYVLSAFG---VTDDSWSKYVSISFIIFAVLIHGVSVRHGVFIQNALGGLKLIMIVLMCFAGLYTLFFYKSTGQVAWDLPVTQVEKDSLLSVSSIATAFISSFFCFSGWDTVHTVTSEIKNPVKTLKVSGPLSLIICFVCYTMMNVAYLKVLTYEEIVSAGPLVGSVLFTKLFGPRVGGKFIAFSIAISAASNILVVIYSISRVNQEIFKEGYLPFSIHMSKNWPFDAPLPSISLCGFITIAWILILPKEGESFNYLVSMDGYGNQFFLLLVAIGLFIWRFKHK----NEVPEIRASTFGVLAIITLSLYMLMAPFFADPSLN--------RVGFLPPYQIMSLLVIVACFFFWLVKFVLLPKFFHYKLLPKITYLHDGLIVTEWVKKPCLC-----------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .:.::. :. . ::*:*:*. .. : .. : : :*.... ::. * : *:*: *.*.*. :: * :* . :: . .: . : :. . : . ::: *: . :*: : *: :. : * * : : .. : :: * ::.: *:. :: *:*:* :.* : * : : * : *::: :: . : : :. :* . :.:* . : : : .*: .:* :* : * . : :: : : : .: : : . . :: . ::: .* . . : : . : . : ", "identical_positions": 33, "similar_positions": 140, "identity": "5.64%" }, { "cls_id": "homologset.agr.RGD:1309195", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4A980-1", "uniprot_id": "D4A980_RAT", "id": "D4A980-1", "name": "Paracaspase", "aln": "MSLWGQPLQASPPPAVQQPLTASSGPSTAPPAGSTLNRLPEPLLRRLSESLDRAPEGRGWRQLAELAGSRGRLRLSCLDLEQCSLKVLEPEGSPSLCLLKLMGEKGCTVPELSDFLQALEHTEVLQLLNPPGLKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPYGNSSELIFNTVHVKDAGFYVCRVNNNSTFEFSQWSQLDVCDVTEVSDSFQGSLDGVSESKLRICVEPQSQKLAPGSALLLQCVAIGSPVPHYQWFKDESPLAHETKKHYTVPYVDLEHEGTYWCHVYNDRDSQDSKKVEIIIG--------------RTDGAVECTEDELNNLGRPDNKEQ-TGQPLAKDKVALLIGNMNYWEHPKLKAPLVDVYELTNLLRQLDFKVVSLLDLTEYEMCNAVDEFLLLLDKGVYGLLYYAGHGYENFGNSFMVPVDAPNPYRSENCLCVQNILKLMQEKETGLNVFLLDMCRKRNDYDDTIPILDALKVTANIVFGYATCQGAEAFEIQHSGLANGIFMKFLKDRLLEDKKITVLLDEVAEDMGKCHLTKGRQALEIRSSLSEKRALTDPIQGAPCSAEALVRNLQWAKAHELPESMCLKFQCGVHIQLGFAAEFSNVMIIYTSIVHKPPEIIMCDAYVTDFPLDLDIDPKHANKGTPEETGSYLVSKELPKHCLYTRLSSLQKLKEHLIFTVCLSYQYSGLEDTVEEKQEVSVGKPLIAKLDMHRGLGRKTCLQACPMPDETCHSSTSTSAGAGHFHSSQDSFHDVYHSQLGNSDSAMPPDRCHCSRTPHAFISNYPPHHYCQFGRS-NVPVETT---DEMPFSFSDRLMISEN-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q2TBA3-1", "uniprot_id": "MALT1_MOUSE", "id": "Q2TBA3-1", "name": "Mucosa-associated lymphoid tissue lymphoma translocation protein 1 homolog", "aln": "MSLWGQPLQASPPLAVRQPPTASSGPSTSPPAGATLNRLPEPLLRRLSESLDRAPEGRGWRQLAELAGSRGRLRLSGLDLEQCSLKVLEPEGSPSLCLLKLMGEKGCTVTELSDFLQALEHTEVLPLLNPPGLKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPYGNSSELVFNTVHVKDAGFYVCRVNNSSTFEFSQWSQLDVCDVAEVTDSFQGSMDGISESRLQICVEPRSQRLVPGSMLLLQCVAIGSPMPHYQWFKDESPLTHETKKHYTVPYVDIEHEGTYWCHVYNDRDSQDSKKAEVTIG--------------RTDEAVECTEDELNNLGHPDNKEQ-TGQPLAKDKVALLIGNMSYWEHPKLKAPLVDVYELTNLLRQLDFKVVSLLDLTEYEMCNAVDEFLLLLDKGVYGLLYYAGHGYENFGNSFMVPVDAPNPYRSENCLCVQNILKLMQEKETGLNVFLLDMCRKRNDYDDTIPILDALKVTANIVFGYATCQGAEAFEIQHSGLANGIFMKFLKDRLLEDKKITVLLDEVAEDMGKCHLTKGRQALEIRSSLSEKRALTDPVQGAPCSAEALVRNLQWAKAHELPESMCLKFQCGVHIQLGFAAEFSNVMIIYTSIVHKPPEIIMCDAYVTDFPLDLDIDPKHANKGTPEETGSYLVSKDLPKHCLYTRLSSLQKLKEHLIFTVCLSYQYSGLEDTVEEKQEVNVGKPLIAKLDMHRGLGRKTCFQACRMPDEPYHSSTSTSAGAGHFHSSQDSFHDVYHSHLGNADSGMPPDRCHCSRTPHTFISNYPPHHYCQFGRS-NVPVETT---DEMPFSFSDRLMISEN-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UDY8-1", "uniprot_id": "MALT1_HUMAN", "id": "Q9UDY8-1", "name": "Mucosa-associated lymphoid tissue lymphoma translocation protein 1", "aln": "MSLLGDPLQALPP------SAAPTGPLLAPPAGATLNRLREPLLRRLSELLDQAPEGRGWRRLAELAGSRGRLRLSCLDLEQCSLKVLEPEGSPSLCLLKLMGEKGCTVTELSDFLQAMEHTEVLQLLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNTSELIFNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPES---FQRSVDGVSESKLQICVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPLTHETKKLYMVPYVDLEHQGTYWCHVYNDRDSQDSKKVEIIIG--------------RTDEAVECTEDELNNLGHPDNKEQTTDQPLAKDKVALLIGNMNYREHPKLKAPLVDVYELTNLLRQLDFKVVSLLDLTEYEMRNAVDEFLLLLDKGVYGLLYYAGHGYENFGNSFMVPVDAPNPYRSENCLCVQNILKLMQEKETGLNVFLLDMCRKRNDYDDTIPILDALKVTANIVFGYATCQGAEAFEIQHSGLANGIFMKFLKDRLLEDKKITVLLDEVAEDMGKCHLTKGKQALEIRSSLSEKRALTDPIQGTEYSAESLVRNLQWAKAHELPESMCLKFDCGVQIQLGFAAEFSNVMIIYTSIVYKPPEIIMCDAYVTDFPLDLDIDPKDANKGTPEETGSYLVSKDLPKHCLYTRLSSLQKLKEHLVFTVCLSYQYSGLEDTVEDKQEVNVGKPLIAKLDMHRGLGRKTCFQTCLMSNGPYQSSAATSGGAGHYHSLQDPFHGVYHSHPGNPSNVTPADSCHCSRTPDAFISSFAHHASCHFSRS-NVPVETT---DEIPFSFSDRLRISEK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BCW4-1", "uniprot_id": "A0A8M2BCW4_DANRE", "id": "A0A8M2BCW4-1", "name": "", "aln": "-------------------------MSESNESSLNINFLKESVLKRLCESLDKANN-KGWRKLGEIVKNDKRFKVSLEDMDMCSLKALKADGSPSRTLLKLIGDQGCIQEELMEFLQIMGHTEALQCLKPPGIQILLQPQSVSVIAGHNLRLSCYAVGASPVQFQWFKKTEEVRSSSSPDLVFSPVQIRDAGFYICRVNCGSTYEFSQWAQVDVLDVPTR----YGLVSMGSEVRLRVLIQPQPQKLLTGDLLYLECGAAGRLLPQYQWYRNGAPIKKANKRKFTVKNVLPEHQGRYRCEICCNNERTWSSEVDVVIANPCLSQMKEARIFPQISGAMECSEDDFLSINKDNSFEK----PYATDKVALLIGNLAYRNHPQLKAPMVDVYDLTNLLRQLNFKVVSLLDLTESEMRNAVEEFLSLLHKGVYGLLYYAGHGYENFGNSFMVPVDAPNPYRSGNCLCVQSILKLMQEKETGLNVFLLDMCRKRNMHDDAMPNV-MLKVTANIVFGYATCQDAEAFELSSSGFTNGVFIKFLKERLLEDEKITVLLDRVAEDMGQFDPTKGKQALEIRSSLSERRSLTDPICHGGYSDATEAHNPLWSKAHELPESKVLDFECGVRIKMDFAAEFSNVLVIYTSIVKKPEEMQSCQAHITDLPLDLDVDPKLMNKETLEETGSFLLSGSLPQHCLYTRLSSLQKLKEELAFTVCLQVQFSSLDDLVQWNMHVNIGKPLTAKLDLYRPTRKNSCQVTCHMPHSPSTSPSHSPGSDRRFHSQEPCCPQPYANPYLNVCEHLHGAQAGYRDFQLNTDHAYQYMPLSPLTNPPSIPIETTDDIDDMQNDFINSLHLYKHP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :. .:* * *.:*:**.* **:* : :***:*.*:. . *:::* *:: ****.*:.:**** ****:*::** ** :*** : ***.* *.***::* ::*:* :*:**: ::*.* *.* . **:**** .:*: ..:.:*:*..*:::*****:**** . *:*****:*:** *:. :. ** :*:: ::* .*:* .*. * *:* * * :*:***::: *: : .*: : * * **:* * *.: :.: *.:.:: *. : . *:**:**:: .:.: :. *: * *.*********: * :**:****:****:********:*********** ** ***:*** **.********************************* ******.************************ :**::* : ***************.*****:. **::**:*:****:*****:*******.******: . ***:***********:*:****: * : .:* *:******** *.*:***:*::.********::****** ** *: *:*::**:*****:*** ** * *****:*:* .**:***************.* *****. *:*.*:* *: : .*.:**** ****::* :::* :* *.. . *.: :... ::** : * . * . . : . : .. .:*:*** *:: .* : * : :: ", "identical_positions": 411, "similar_positions": 213, "identity": "48.24%" }, { "cls_id": "homologset.agr.RGD:1309196", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZBQ1-1", "uniprot_id": "D3ZBQ1_RAT", "id": "D3ZBQ1-1", "name": "", "aln": "MAEAPASPVP------------LSPLEVELDPEFEPQSRPRSCTWPLQRPELQASPAKPSGETAADSMIPEEDDDEDDEDSGGRGSSAMVIGGG-VSSALGSGLLLEDSARLLSPGGQDLGTGPASSAGALSGGTQTQLQPQQPLPPPQPGAAGGSGQPRKCSSRRNAWGNLSYADLITRAIESSPDKRLTLSQIYEWMVRCVPYFKDKGDSNSSAGWKNSIRHNLSLHSRFMRVQNEGTGKSSWWIINPDGGKSGKAPRRRAVSMDNSNKYTKSRGRAAKKKAALQAA---------PESADDSPSQLSKWPGSPTSRSSDELDAWTDFRSRTNSNASTVSGRLSPILASTELDDVQDDDGPLSPMLYSSSASLSPSVSKPCTVELPRLTDMAGTMNLNDGLAENLMDDLLDNIALPPSQASPPGGLMQRSSSFPYTAKSSGLGSPTSSFNSTVFGPASLNSLR-----QSPMQTIQENRPATFSSVSHYGNQTLQDLLTSDSLSHSDVMMTQSDPLMSQASTAVSAQNARRNVMLRNDPMMSFAAQPTQGSLVNQNLLHHQHQTQGALGGSRALSNSVSNMGLSDSSSLGSAKHQQQSPVSQSMQTLSDSLSGSSLYSASANLPVMGHDKFPSDLDLDMFNGSLECDMESIIRSELMDADGLDFNFDSLISTQNVVGLNVGNFTGAKQASSQSWVPG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WVH4-1", "uniprot_id": "FOXO3_MOUSE", "id": "Q9WVH4-1", "name": "Forkhead box protein O3", "aln": "MAEAPASPVP------------LSPLEVELDPEFEPQSRPRSCTWPLQRPELQASPAKPSGETAADSMIPEEDDDEDDEDGGGRASSAMVIGGG-VSSTLGSGLLLEDSAMLLAPGGQDLGSGPASAAGALSGGTPTQLQPQQPLPQPQPGAAGGSGQPRKCSSRRNAWGNLSYADLITRAIESSPDKRLTLSQIYEWMVRCVPYFKDKGDSNSSAGWKNSIRHNLSLHSRFMRVQNEGTGKSSWWIINPDGGKSGKAPRRRAVSMDNSNKYTKSRGRAAKKKAALQAA---------PESADDSPSQLSKWPGSPTSRSSDELDAWTDFRSRTNSNASTVSGRLSPILASTELDDVQDDDGPLSPMLYSSSASLSPSVSKPCTVELPRLTDMAGTMNLNDGLAENLMDDLLDNIALPPSQPSPPGGLMQRGSSFPYTAKSSGLGSPTGSFNSTVFGPSSLNSLR-----QSPMQTIQENRPATFSSVSHYGNQTLQDLLASDSLSHSDVMMTQSDPLMSQASTAVSAQNARRNVMLRNDPMMSFAAQPTQGSLVNQNLLHHQHQTQGALGGSRALSNSVSNMGLSDSSSLGSAKHQQQSPASQSMQTLSDSLSGSSLYSASANLPVMGHDKFPSDLDLDMFNGSLECDMESIIRSELMDADGLDFNFDSLISTQNVVGLNVGNFTGAKQASSQSWVPG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43524-1", "uniprot_id": "FOXO3_HUMAN", "id": "O43524-1", "name": "Forkhead box protein O3", "aln": "MAEAPASPAP------------LSPLEVELDPEFEPQSRPRSCTWPLQRPELQASPAKPSGETAADSMIPEEEDDEDDEDGGGRAGSAMAIGGGGGSGTLGSGLLLEDSARVLAPGGQDPGSGPATAAGGLSGGTQALLQPQQPLPPPQPGAAGGSGQPRKCSSRRNAWGNLSYADLITRAIESSPDKRLTLSQIYEWMVRCVPYFKDKGDSNSSAGWKNSIRHNLSLHSRFMRVQNEGTGKSSWWIINPDGGKSGKAPRRRAVSMDNSNKYTKSRGRAAKKKAALQTA---------PESADDSPSQLSKWPGSPTSRSSDELDAWTDFRSRTNSNASTVSGRLSPIMASTELDEVQDDDAPLSPMLYSSSASLSPSVSKPCTVELPRLTDMAGTMNLNDGLTENLMDDLLDNITLPPSQPSPTGGLMQRSSSFPYTTKGSGLGSPTSSFNSTVFGPSSLNSLR-----QSPMQTIQENKPATFSSMSHYGNQTLQDLLTSDSLSHSDVMMTQSDPLMSQASTAVSAQNSRRNVMLRNDPMMSFAAQPNQGSLVNQNLLHHQHQTQGALGGSRALSNSVSNMGLSESSSLGSAKHQQQSPVSQSMQTLSDSLSGSSLYSTSANLPVMGHEKFPSDLDLDMFNGSLECDMESIIRSELMDADGLDFNFDSLISTQNVVGLNVGNFTGAKQASSQSWVPG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q95V55-1", "uniprot_id": "FOXO_DROME", "id": "Q95V55-1", "name": "Forkhead box protein O", "aln": "MMDGYAQEWPRLTHTDNGLAMDQLGGDLPLDVGFEPQTRARSNTWPCPRPENFVEPTDELDSTKAS--------------------------------------------------------------------------NQQLAPGDSQQAIQNANAAKKNSSRRNAWGNLSYADLITHAIGSATDKRLTLSQIYEWMVQNVPYFKDKGDSNSSAGWKNSIRHNLSLHNRFMRVQNEGTGKSSWWMLNP-EAKPGKSVRRRAASMETS-RYEKRRGRAKKRVEALRQAGVVGLNDATPSPSSSVSEGLDHFPESP-LHSGGGFQLSPDFRQRASSNASSCG-RLSPIRAQDLEPDWGFPVDYQNTTMTQAHAQALEELTGTMADELTLCNQQQQGFSAASGLPSQPPPPPYQ-----PPQHQQAQQQQQQQSPYALNGPASGYNTLQPQSQCLLHRSLNCSCMHNARDGLSPNSVTTTMSPAYPNSEPSSDSLNTYSNVVLDGPADTAALMVQQQ-QQQQQQQQLSASLEGQCLEVLNNEAQPIDEFNLENFPVGNLECNVEELLQQEMSYGGLLDINIPLATVNTNLVNSSSGPLSISNISNLSNISSNSGSSLSLNQLQAQLQQQQQQQQAQQQQQAQQQQQQHQQHQQQLLLNNNNNSSSSLELATQTATTNLN-ARVQYSQPSVVTSPPSWVH-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :. *. * :: ** ****:*.** *** *** ..*:. ..* *. ** * . * .:. .:* *****************:** *:.**************: ***************************.****************::** .*.**: ****.**:.* :* * **** *: **: * *..:.. .. *.::* ** :*.. :: .***.*:.****: . ***** *. : .. : .: *. .:: . : **. .: :. .**..: : *.* . . *: *.:. . .** .: . :. :. . . ..:: ** .. ** .* . .. . . :. *. :.: .:*.*.: .* . :**. : : : *: .: :. *.: : :. * :. . *. .:. :. . .*: . * *: : *:* *. ** . .*:* ::: ..: : : . . : :. : : : .. .::: : :* *: .* : :*. *** ", "identical_positions": 188, "similar_positions": 187, "identity": "26.9%" }, { "cls_id": "homologset.agr.RGD:1309197", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q4V8C2-1", "uniprot_id": "ZW10_RAT", "id": "Q4V8C2-1", "name": "Centromere/kinetochore protein zw10 homolog", "aln": "------MASFVTEVLAHSG--SLEKEDLGTRISRLTRRVEEIKGEVCNMISKKYSEFLPTMQSAQALVTQVDTLSNDIDQLKSRIETEVCRDLHISTVEFTNLKQRLERDSVVLNLLKQLQE-FSSAIEEYNSALAEKKYIPAAR-LLEEAQECLKLLKSKKCFDLKMLKSLSMELTVQKQNILYHLGEDWQKLVVWKFPPSKDTSSLESCLQTELHLCTEQPEKE-MTPLPSISSVLLAFSILGELPTKLKS---FGQMLLKYILKPLVTCP--SLHAVIERQPNSVSICFQSLATDSEHPPPPEAFAKIQLVLEVLQKQLLDLPLDADLEIGKVPEIVLAEMLGEVIWEDLSDCLIRNCLVYSIPTNSSKLQQYEEIIQSTEEFEKSLKEMRFLKGDTTDLLKYARNINSHFANKKCQDVIVAARHLMTSEIHNTVKIGPDCEETLPDLPSPDADHRLQVQ-VCKVQFTDAGNLEPETSLDPRSFSLPTCRISEAVKKLMELAYQTLLEATTSS-DQCAVQLFYSVRNIFHLFHDVVPTYHKENLQKLPQLAAIHHNNCMYIAHHLLTLGHQFRSRLTPI--LCDGTTTFVDLVPGFRRLGTECFLAQMRTQKGELLERLSSARSFANMDDEENYSAASKAVRQVLHQLKRLGIVWQDVLPVNIYCKAMGTLLNTVIAEMIGRITALEDISTEDGDRLYSLCKTVMDEGPQVFAPLSDENKNKKYQEEVPVYVSKWMPFKELMIMLQASLQEIGDRWADGKGPLATAFPSSEVKALIRALFQNTERRAAALAKIK---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54692-1", "uniprot_id": "ZW10_MOUSE", "id": "O54692-1", "name": "Centromere/kinetochore protein zw10 homolog", "aln": "------MASFVTEVLAHSG--SLEKEDLGTRISRLTRRVEEIKGEVCNMISKKYSEFLPTMQSAQALVTQVDTLSNDIDQLKSRIETEVCRDLHISTVEFTNLKQQLERDSVVLTLLKQLQE-FSSAIEEYNSALAEKKYIPAAR-HLEEAQECLKLLKSRKCFDLKMLKSLSMELTVQKQNILYHLGEDWQKLVVWKFPPAKDTSSLESCLQTELHLCTEQPEKEDMTPLPSISSVLLAFSILGELPTKLKS---FGQMLLKYILKPLVTCP--SLHAVIERQPSSVSICFESLTTDLEHPSPPEAFAKIRLVLEVLQKQLLDLPLDADLEIGKVPGIVLAEMLGEGIWEDLSECLIRNCLVYSIPTNSSKLQEYEEIIQSTEEFEKFLKEMRFLKGDTTDLLKYARNINSHFANKKCQDVIVAARNLMTSEIHNTVKIGPDCKEALPDLPSPDADHKLQVQTVCKAQFTDAGNLEPETSLDPQSFSLPTCRISEAVKKLMELAYQTLLEATTSS-DQCAVQLFYSVRNIFHLFHDVVPTYHKENLRKLPQLAAIHHNNCMYIAHHLLTLGHQFRLRLAPI--LCDGTTTFVDLVPGFRRLGTECFLAQMQAQKGELLERLSSARSFANMDDEENYSAASKAVRQVLHQLRRLGIVWQDVLPVNIYCKAMGTLLNTAIAEMMSRITALEDISTEDGDRLYSLCKTVMDEGPQVFAPLSDENKNKKYQEEVPVYVSKWMPFKELMIMLQASLQEIGDRWADGKGPLATAFPSSEVKALIRALFQNTERRAAALAKIK---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43264-1", "uniprot_id": "ZW10_HUMAN", "id": "O43264-1", "name": "Centromere/kinetochore protein zw10 homolog", "aln": "------MASFVTEVLAHSG--RLEKEDLGTRISRLTRRVEEIKGEVCNMISKKYSEFLPSMQSAQGLITQVDKLSEDIDLLKSRIESEVRRDLHVSTGEFTDLKQQLERDSVVLSLLKQLQE-FSTAIEEYNCALTEKKYVTGAQ-RLEEAQKCLKLLKSRKCFDLKILKSLSMELTIQKQNILYHLGEEWQKLIVWKFPPSKDTSSLESYLQTELHLYTEQSHKEEKTPMPPISSVLLAFSVLGELHSKLKS---FGQMLLKYILRPLASCP--SLHAVIESQPNIVIIRFESIMTNLEYPSPSEVFTKIRLVLEVLQKQLLDLPLDTDLENEKTSTVPLAEMLGDMIWEDLSECLIKNCLVYSIPTNSSKLQQYEEIIQSTEEFENALKEMRFLKGDTTDLLKYARNINSHFANKKCQDVIVAARNLMTSEIHNTVKIIPDSKINVPELPTPDEDNKLEVQKVSNTQYHEVMNLEPENTLDQHSFSLPTCRISESVKKLMELAYQTLLEATTSS-DQCAVQLFYSVRNIFHLFHDVVPTYHKENLQKLPQLAAIHHNNCMYIAHHLLTLGHQFRLRLAPI--LCDGTATFVDLVPGFRRLGTECFLAQMRAQKGELLERLSSARNFSNMDDEENYSAASKAVRQVLHQLKRLGIVWQDVLPVNIYCKAMGTLLNTAISEVIGKITALEDISTEDGDRLYSLCKTVMDEGPQVFAPLSEESKNKKYQEEVPVYVPKWMPFKELMMMLQASLQEIGDRWADGKGPLAAAFSSSEVKALIRALFQNTERRAAALAKIK---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W4X9-1", "uniprot_id": "ZW10_DROME", "id": "Q9W4X9-1", "name": "Centromere/kinetochore protein zw10", "aln": "MEEEAPRFNVLEEAFNGNGNGCANVEATQSAILKVLTRVNRFQMRVRKHIEDNYTEFLPNNTSPDIFLEESGSLNREIHDMLENLGSEGLDALDEANVKMAGNGRQLREILLGLGVSEHVLR-IDELFQCVEEAKATKDYLVLLD-LVGRLRAFIYGDDS--------VDGDAQVATPEVRRIFKALECYETIKVKYHVQAYMLQQSLQERFDRLVQLQCKSFPTSRCVTLQVSRDQTQLQDIVQALFQEPYNPARLCEFLLDNCIEPVIMRP--VMADYSEEADGGTYVRLS-LSYATKEPSSAHVRPNYKQVLENLRLLLHTL---AGINCSVSRDQHVFGIIGDHVKDKMLKLLVDECLIPAVPESTEEYQTSTLCEDVAQLEQLLVDSFIINPEQDRALGQFVEKYETYYRNRMYRRVLETAREIIQRDLQDMVLVAPN-------------------------------NHSAEVANDP--FLFPRCMISKSAQDFVKLMDRILRQPTDKLGDQEADPIAGVISIMLHTYINEVPKVHRKLLESIPQQAVLFHNNCMFFTHWVAQHAN-------------KGIESLAALAKTLQATGQQHFRVQVDYQSSILMG---IMQEFEFESTHTLGSGPLKLVRQCLRQLELLKNVWANVLPETVYNATFCELINTFVAELIRRVFTLRDISAQMACELSDLIDVVLQRAPTLFREPNE-----------VVQVLSWLKLQQLKAMLNASLMEITELWGDGVGPLTASYKSDEIKHLIRALFQDTDWRAKAITQIV---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53847-1", "uniprot_id": "DSL1_YEAST", "id": "P53847-1", "name": "Protein transport protein DSL1", "aln": "----------MESLFPNKG------EIIRELLKDPLILKNDSKRSNGSELELDSSDLLQREAILANELNILDNLKTFLNLIKEVKTNLNILELENCYYSLQSLRKKMRNNAAYLKQSFNFQQSISTYVDTLHLELVSTLYKILTNGFWKITENSIQFTPTVEWGKDKVHIEYDTFMDFVAQQYFPKGSLDNQAWFILDMTSADSQEQVRAKLNTIMKEYMNLSRIVSMIKNSIFISGKEISYENEKNILVFSKSSSHGQHCVSTVLTSFEAVCDFMLDGLAFRDRKTLSYELGPLFNTEFTKFVKNNASIILESLDSPLKNLVSVINNKLTRLVAKSEVTNWTHSGKEIQDLLMNKQLYYNLLLDKVLES-HISEIRSIFEDPKKSWQNLEVVELTTSNTNTMSEKIGKNDSDVQNEKELHNAVSKDDDWNWEVEDDDADAWGDEIDVN---------------IDDEEEKTNQEKEKEPEEEENAWDEAWAIDENIDDASLENGKEHLKAHDVGSLDKDHIEVTQLPKLFLAISQNFKSSFADSHVDEQYFAYKYNLLQTSYMAMCTANFSHNWCQLYVDMRYLIERDEKLYRIKELTRNLLETKLNMKYRIVCQLIRHQLTEFRENE--RNPSWDATIEKLLPYILKEIVRPLQKIRGEEGSRYLLSFLNFLYNDCVTKEILKWQIISEVNSENLGELVSLLVNNTDIQLLAKE---------------PSYKKMREKFATMGKFLPLHLKEIMEMFYNG---DFYLFATDELIQWIELLFADTPLRRNAIDDIYEIRGTALDD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : .* * : : : . :. . :::* : ..*. :. : . . *. . .: . :::.. * :. . :. .: . . . * . : : :. : . .. . ..:. :: :: : . . : :. : .. : : : . . *: * : . *. : : : . : *: .: . . : .: :. . : : : : : :: *. : . ::.: . : . * : : . . .: . :: . * *: : :: : .. . : . : ::: .: . .: : : : : : :. : * : *::: . : * * ::: : : : ::.:: .* .* : : : :* * ** : : :* : :.*: *. ** :* * *: .* ", "identical_positions": 34, "similar_positions": 183, "identity": "4.22%" }, { "cls_id": "homologset.agr.RGD:1309198", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4A944-1", "uniprot_id": "D4A944_RAT", "id": "D4A944-1", "name": "U5 small nuclear ribonucleoprotein 40 kDa protein", "aln": "MLEIDWLLSSGSSGGRTQLKPIAQRLLQAARLLAAPRVVVAAMIEQQKRKGPELPLVPVKRPRHELLLGAAGSGPGAGQQQATPGALLQTGPPRCSSLQAPIMLLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWSVYGDCDNYATLKGHSGAVMELHYNTDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRKKAAIQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVYVWDTTSRRILYKLPGHAGSINEVAFHPDEPIILSASSDKRLYMGEIQ-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96DI7-1", "uniprot_id": "SNR40_HUMAN", "id": "Q96DI7-1", "name": "U5 small nuclear ribonucleoprotein 40 kDa protein", "aln": "------------------------------------------MIEQQKRKGPELPLVPVKRQRHELLLG-AGSGPGAGQQQATPGALLQAGPPRCSSLQAPIMLLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRKKAAIQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVYVWDTTSRRILYKLPGHAGSINEVAFHPDEPIIISASSDKRLYMGEIQ-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PE01-1", "uniprot_id": "SNR40_MOUSE", "id": "Q6PE01-1", "name": "U5 small nuclear ribonucleoprotein 40 kDa protein", "aln": "------------------------------------------MIEQQKRKGPELPLVPVKRPRHELLLGAAGAGPGAGPQQATPGALLQAGPPRCSSLQAPIMLLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRKKAAVQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVYVWDTTSRRVLYKLPGHAGSINEVAFHPDEPIILSASSDKRLYMGEIQ-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VPL0-1", "uniprot_id": "Q9VPL0_DROME", "id": "Q9VPL0-1", "name": "U5 small nuclear ribonucleoprotein 40 kDa protein", "aln": "-------------------------------------------MGTKRPNNSVILAQEAKRSKNDLMAYTNRDK-----------ALLESGVRRTSNLQAPIMQLEGHEGEIFTAEFHPEGELLLSSGFDRQIYIWQVYEDCENVMAMSGHSGAVMEAHFTPDGSHIFTCSTDKTLAFWDIATGQRQRRFKGHGNFVNSVQGSRRGQQLLCSGSDDRTIKIWDARKKHAAHTLESPFQVTAVCFGDTGEQVISGGIDNEVKIWDIRKQAVLHHLRGHSDTITGMSLSPEGDFILTNAMDNTLRVWDVRPYAPGERCVKVFQGHQHNFEKNLLRCAWSPGSDKITSGSADRHVYIWDVNTRRILYKLPGHNGSVNAVDFSPKEPLILSGSSDKTLYLGEIDE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: :.. : .** :::*: ***::* * *.****** *.*****:: .:***:*. * *:**** * :*.** **:* ::.******** *:..*** :*:.*****:*.** **:* :*:*** .**** :*** **:*:**** *:*:** *** * :*::..:** ** *.**.:*:*******::*:**:*:: : : :***:*::**:***.**.::*:******:*******:** *****:***: **********:***...**::*****.**:**..:**:******* **:* * * *.**:*:*.**** **:***: ", "identical_positions": 195, "similar_positions": 97, "identity": "48.63%" }, { "cls_id": "homologset.agr.RGD:1309199", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U2T8-1", "uniprot_id": "CIR1_RAT", "id": "Q5U2T8-1", "name": "Corepressor of RBPJ and splicing regulator", "aln": "MGKSFANFMCKKDFHPASKSNIKKVWMAEQKISYDKKKQEELMQQYLKEQESYDNRLLMG-DERVKNGLNFMYEAPPGVKKENKEKEETEGETEYKFEWQKG--APREKYAKDDMNIRDQPFGIQVRNVRCIKCHKWGHVNTDRECPLFGLSGINASSVPTD-GSGPSMHPSELIAEMRNSGFALKRNVLG-RNLTANDPSQDYVASDGE-------EDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKKSDKKKKKLQKSKNKHKKHKKSSSSSSSSSSSSSSSSSSSSSSSSSSTSSSETDSSSESDNKEKK-EKEKRKKRKKTKCSGNKSGDCKE-YKSKN-MLYEELSSSHSDRGKAQEKLRLLKQESSGENSTWVHSGSDRKSRSHQHSPERKGSDRNGG--SRSRSRAEGSRRSRSRSPCGQKHREREARSRPHQSPSEEQKGRKGTRSHGDSEHRRERAR---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DA19-1", "uniprot_id": "CIR1_MOUSE", "id": "Q9DA19-1", "name": "Corepressor of RBPJ and splicing regulator", "aln": "MGKSFANFMCKKDFHPASKSNIKKVWMAEQKISYDKKKQEELMQQYLKEQESYDNRLLMG-DERVKNGLNFMYEAPPGVKKENKEKEETEGETEYKFEWQKG--APREKYAKDDMNIRDQPFGIQVRNVRCIKCHKWGHVNTDRECPLFGLSGINASSVPTD-GSGPSMHPSELIAEMRNSGFALKRNVLG-RNLTANDPSQDYVASDCE-------EDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKKSDKKKKKLQKSKNKHKKRKNKSPSSSSSSSSSSSSSSSSSSSSSSSSETS--DSSSESDNKEKKREKEKRKKKKKTKCSESKSSDCKE-DKPKN-MLYEELSSSHSDRGKAQEKLRFPKQESSGENSMWVHSASDRTSRSHRHSPEKKGSDRNRGIRSRSRSRAESSRRSRSRSPYRQKHR--EVRSRPHRSPSEEQKGRKGTRSHGEGDHRREHVR---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86X95-1", "uniprot_id": "CIR1_HUMAN", "id": "Q86X95-1", "name": "Corepressor of RBPJ and splicing regulator", "aln": "MGKSFANFMCKKDFHPASKSNIKKVWMAEQKISYDKKKQEELMQQYLKEQESYDNRLLMG-DERVKNGLNFMYEAPPGAKKENKEKEETEGETEYKFEWQKG--APREKYAKDDMNIRDQPFGIQVRNVRCIKCHKWGHVNTDRECPLFGLSGINASSVPTD-GSGPSMHPSELIAEMRNSGFALKRNVLG-RNLTANDPSQEYVASEGE-------EDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKK--DRKKKKFQKSRSKHKKHK----------SSSSSSSSSSSSSSTETSESS---SESESNNKEKK---IQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSREDSKWSHSDSDKKSRTHKHSPEKRGSERKEG-SSRSHGREERSRRSRSRSPGSYKQR--ETRKRAQRNPGEEQSRRNDSRSHGTDLYRGEKMYREHPGGTHTKVTQRE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VVU4-1", "uniprot_id": "Q9VVU4_DROME", "id": "Q9VVU4-1", "name": "CBF1-interacting co-repressor CIR N-terminal domain-containing protein", "aln": "MGKGFNNYMCKKFFHPASRDNLKRVWMAEQQAEAYKKKQEELRNQYEKEQNLHENKAMLSKDSKDKLSVNFMYEPPPGVRK---EREKDDNEPEYKFEWQRKYNAPRESYCKGDTEIRDQPFGIQVRNVRCLKCHKWGHINTDKECTMYSISMSEARKLHAETEASDIMAKNVLEEQMKEDGLMMKRSAQELQSIRAIQQQHQLVPSDGEKDAHADDQNPELVFLKSLSKKQKLKLLKKLEKIERMKRKG---EGIKKPTKRKSKKERHE------------------------------------KDSKKKKSK---KDKSSRKDKKGSVSNSSD----------------SSSSSDSSDSEDN-----HKSNHRDD---KRNGHQRTRDSDHSYQRRSNENRHR-RDRSRSRD----RSRSLSRDRRRER--ERRDRSRR-----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***.* *:**** *****:.*:*:******: . ******* :** ***: ::*: ::. *.: * .:*****.***.:* *:*: :.*.*******: ****.*.*.* :***************:*******:***:**.::.:* :* .: :: :. * . * :*::.*: :**.. :.: * : .:: *.*: * ::**: *****:.*** ***:**:::*: *:* . ** * :.*::::: .:*.:*:.* .:..:*..* * :..* *** : .:::: ::*. .:. : ..: :* ** :::..:.. .**:.* **** * :.* * *.*.:: ", "identical_positions": 150, "similar_positions": 135, "identity": "31.06%" }, { "cls_id": "homologset.agr.RGD:1309202", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9BVJ7-1", "uniprot_id": "DUS23_HUMAN", "id": "Q9BVJ7-1", "name": "Dual specificity protein phosphatase 23", "aln": "MGVQPPNFSWVLPGRLAGLALPRLPAHYQFLLDLGVRHLVSLTERGPPHSDSCPGLTLHRLRIPDFCPPAPDQIDRFVQIVDEANARGEAVGVHCALGFGRTGTMLACYLVKERGLAAGDAIAEIRRLRPGSIETYEQEKAVFQFYQRTK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZRL3-1", "uniprot_id": "D3ZRL3_RAT", "id": "D3ZRL3-1", "name": "Dual specificity protein phosphatase 23", "aln": "MGVQPPNFSWVLPGRLAGLALPRLPAHYQFLLDLGVRHLVSLTERGPPHSDSCPGLTLHRLRIPDFCPPAPEQIDQFVKIVDEANARGEAVGVHCALGFGRTGTMLACYLVKEQGLAAGEAIAEIRRLRPGSIETYEQEKAVFQFYQRTK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6NT99-1", "uniprot_id": "DUS23_MOUSE", "id": "Q6NT99-1", "name": "Dual specificity protein phosphatase 23", "aln": "MGVQPPNFSWVLPGRLAGLALPRLPAHYQFLLDQGVRHLVSLTERGPPHSDSCPGLTLHRMRIPDFCPPSPEQIDQFVKIVDEANARGEAVGVHCALGFGRTGTMLACYLVKERALAAGDAIAEIRRLRPGSIETYEQEKAVFQFYQRTK", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "********************************* **************************:********:*:***:**:**********************************:.****:******************************", "identical_positions": 141, "similar_positions": 8, "identity": "94.0%" }, { "cls_id": "homologset.agr.RGD:1309203", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AHM8-1", "uniprot_id": "A0A8I6AHM8_RAT", "id": "A0A8I6AHM8-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------MFPQPPRRVQRPGLMG--LESEHHSWGPWNAIMETESEQNSSSTNGSSSSGASSRPQIAQMSLYERQAVQALQALQRQPNAAQYFHQFMLQQQLSNAQLHSLAAVQQATIAASRQASSPNSSTAQQQTATTQASINLATTSAAQLISRSQSVS------------SPSATTLTQSVLLGN----------------TTSPPLNQSQAQMYLRPQLGNLLQVN-----------RTLGRNVPLASQLILMPNG-----------------AVAAVQQEVPPAQSP-------------------------GVHADADQVQNLAVRNQQAS-----AQGPQIPGSTQKAIPPGASPVSG-LSQASSQALAVAQAS------GASGQSLNLSQAGGGSGNSLPGSMGPGGGGQAPGG------------------------------------------------------------------------------------LGQLPSSGLAGGNCPRKGTGVVQPLPAAQTVTVSQGSQTEAESAAAKKAE-------------------------GDGSSQQSVGMNLTRTATPAPSQTLISSATYTQIQPHS-----------LIQQQQQIHLQQKQVVIQQQ------------------IAIHHQQQFQHRQSQLLHTATHLQLAQQQQQQQQQQQQQQQQQQQQQQQQQQQQQATTLAAPQPPQVPPTQQVPPSQSQQQ------------------------------------------------------AQTLVVQPMLQSSPLSLPPEPTPKPP------------------------IPIQSKPPVAPIKPPQLGAAKMSATQQPPPHIPVQVVGTRQPGTAQAQALGLAQLAAAVPTSRG-----------------------------MPGAVQPGQAHLASSQP--------------------------SSQ-APGALQECPPALATGMTLAPVQGTAHVVKGGPTASSP-------VVAQVPAAFYMQSVHLPGKAQTLAVKRKAESEEEREDLSALGSVLPTKASPAAESPKVIEEKNSLVEKAEPVASLNANPPNSDLVALAPTPSAPPPTLALVSR--------------------QMGDSKPPQAIVKPQILTHIIEGFVIQEGAEPFPVGCSQFLKETEKPLPAGLPTGLNESQSGGPLGGDSPCVDLDKKANLLKCEYCGKYAPAEQFRGSKRFCSMTCAKRYN-----VSCSHQFRLKR---------KKMKEFQEASYARVRRRGPRRSSSDIARAKIQGKRHRGQEDSSRGSDNSSYDEALSPTSPGPLSVRAGHGERDLGNTITTPSTPELQGINPVFLSSNPSQWSVEEVYEFIASLQGCQEIAEEFRSQEIDGQALLLLKEEHLMSAMNIKLGPALKICAKINVLKET------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q64028-1", "uniprot_id": "PHC1_MOUSE", "id": "Q64028-1", "name": "Polyhomeotic-like protein 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------METESEQNSSSTNGSSSSGASSRPQIAQMSLYERQAVQALQALQRQPNAAQYFHQFMLQQQLSNAQLHSLAAVQQATIAASRQASSPNSSTAQQQTATTQASMNLATTSAAQLISRSQSVS------------SPSATTLTQSVLLGN----------------TTSPPLNQSQAQMYLRPQLGNLLQVN-----------RTLGRNVPLASQLILMPNG-----------------AVAAVQQEVPPAQSP-------------------------GVHADADQVQNLAVRNQQAS-----AQGPQMPGSTQKAIPPGASPVSG-LSQTSSQALAVAQASS-----GASGQSLNLSQAGGGSGNSLPGSMGPGGGGQAPGG------------------------------------------------------------------------------------LGQLPSSGLTGGSCPRKGTGVVQPLPAAQTVTVSQGSQTEAESAAAKKAE-------------------------ADGSGQQSVGMNLTRTATPAPSQTLISSATYTQIQPHS-----------LIQQQQQIHLQQKQVVIQQQ------------------IAIHHQQQFQHRQSQLLHTATHLQLAQQQQQQQQQQQQQQQQQQQQ-------QQGTTLTAPQPPQVPPTQQVPPSQSQQQ------------------------------------------------------AQTLVVQPMLQSSPLTLPPEPTSKPP------------------------IPIQSKPPVAPIKPPQLGAAKMSATQQPPPHIPVQVVGTRQPGSAQAQALGLAQLAAAVPTPRG-----------------------------ITGAVQPGQAHLASSPP--------------------------SSQAAPGALQECPPALAAGMTLAPVQGTAHVVKGGPTASSP-------VVAQVPAAFYMQSVHLPGKAQTLAVKRKAESEEERDDLSALASVLPTKASPAAESPKVIEEKNSLGEKAEPVASLNANPPNSDLVALAPTPSAPPPTLALVSR--------------------QMGDSKPPQAIVKPQILTHIIEGFVIQEGAEPFPVGCSQFLKETKKPLQAGLPTGLNESQPSGPLGGDSPSVELEKKANLLKCEYCGKYAPAEQFRGSKRFCSMTCAKRYN-----VSCSHQFRLKR---------KKMKEFQEASYARVRRRGPRRSSSDIARAKIQGKRHRGQEDSSRGSDNSSYDEALSPTSPGPLSVRAGHGERDLGNTITTPSTPELQGINPVFLSSNPSQWSVEEVYEFIASLQGCQEIAEEFRSQEIDGQALLLLKEEHLMSAMNIKLGPALKICAKINVLKET------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P78364-1", "uniprot_id": "PHC1_HUMAN", "id": "P78364-1", "name": "Polyhomeotic-like protein 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------METESEQNSNSTNGSSSSGGSSRPQIAQMSLYERQAVQALQALQRQPNAAQYFHQFMLQQQLSNAQLHSLAAVQQATIAASRQASSPNTSTTQQQTTTTQASINLATTSAAQLISRSQSVS------------SPSATTLTQSVLLGN----------------TTSPPLNQSQAQMYLRPQLGNLLQVN-----------RTLGRNVPLASQLILMPNG-----------------AVAAVQQEVPSAQSP-------------------------GVHADADQVQNLAVRNQQAS-----AQGPQMQGSTQKAIPPGASPVSS-LSQASSQALAVAQASS-----GATNQSLNLSQAGGGSGNSIPGSMGPGGGGQAHGG------------------------------------------------------------------------------------LGQLPSSGMGGGSCPRKGTGVVQPLPAAQTVTVSQGSQTEAESAAAKKAE-------------------------ADGSGQQNVGMNLTRTATPAPSQTLISSATYTQIQPHS-----------LIQQQQQIHLQQKQVVIQQQ------------------IAIHHQQQFQHRQSQLLHTATHLQLAQQQQQQQQQQQQQQQP------------QATTLTAPQPPQVPPTQQVPPSQSQQQ------------------------------------------------------AQTLVVQPMLQSSPLSLPPDAAPKPP------------------------IPIQSKPPVAPIKPPQLGAAKMSAAQQPPPHIPVQVVGTRQPGTAQAQALGLAQLAAAVPTSRG-----------------------------MPGTVQSGQAHLASSPP--------------------------SSQ-APGALQECPPTLAPGMTLAPVQGTAHVVKGGATTSSP-------VVAQVPAAFYMQSVHLPGKPQTLAVKRKADSEEERDDVSTLGSMLPAKASPVAESPKVMDEKSSLGEKAESVANVNANTPSSELVALTPAPSVPPPTLAMVSR--------------------QMGDSKPPQAIVKPQILTHIIEGFVIQEGAEPFPVGCSQLLKESEKPLQTGLPTGLTENQSGGPLGVDSPSAELDKKANLLKCEYCGKYAPAEQFRGSKRFCSMTCAKRYN-----VSCSHQFRLKR---------KKMKEFQEANYARVRRRGPRRSSSDIARAKIQGKCHRGQEDSSRGSDNSSYDEALSPTSPGPLSVRAGHGERDLGNPNTAPPTPELHGINPVFLSSNPSRWSVEEVYEFIASLQGCQEIAEEFRSQEIDGQALLLLKEEHLMSAMNIKLGPALKICAKINVLKET------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W523-1", "uniprot_id": "Q9W523_DROME", "id": "Q9W523-1", "name": "", "aln": "MPHGFGAAPSVSVSGDTESESATTIRTPPPS--------PEATTSVKVNSTTRVDP--------------------------------QRPLRCLETLAQKAGISFDEDFAKSPSQSP---SSKAARGS---------------VGTPSIRRRHPLLPLSSRSPSAPDS---------KTTGRKLEKSQSPAQQVAAATNVPLQISPEQLQQLYANNPYAIQVKQEFPTHTTSGSGTELKHATNIMEVQQQLQLQQQLSEANGGGAASAGAGGAASPANSQQSQQQQHSTAISTMSPMQLAAATGGVGGDWTQGRTVQLMQPSTSFLYPQMIVSGNLLHPGGLGQQPIQVITAGKPFQGNGPQMLTTTTQNAKQMIGGQAGFAGGNYATCIPSNHNQSPQTVLISPVNVISHSPQQQQNLLQSMAAAAQQQQLTQQQQQQLNQQQQQLNQQQQQQQLTAALAKVGVDAQGKLAQKVVQKVTTTSSTVQAATGPGSTGSTQTQQVQQVQQQQQQTTQTTQQCVQVSQSTLPVGVGGQSVQTAQLLNAGQAQQMQIPWFWQNAAGLQPFGSNQIILRNQPDGTQGMFIQQQPATQTLQTQQNQIIQCNVTQTPTKARTQLDALAPKQQQQQQQVGTTNQTQQQQLAVATAQLQQQQQQLTAAALQRPGAPVMPHNGTQVRPASSVSTQTAQNQSLLKAKMRNKQQPVRPALATLKTEIGQVAGQNKVVGHLTTVQQQQQATNLQQVVNAAGNKMVVMSTTGTPITLQNGQTLHAATAAGVDKQQQQLQLFQKQHILQQQ-MLQQQIAAIQMQQQQAAVQAQQQQQQQVSQQQQVNAQQQQAVAQQQQAVAQAQQQQREQQQQVAQAQAQHQQALANATQQILQVAPNQFITSHQQQQQQQLHNQLIQQQLQQQAQAQVQAQVQAQAQQQQQQREQQQNIIQQIVVQQSTGATSQQQQQQPQQQSGQLQLSSVPFSVSPSMTAEDIAGITSSALQEALSVSGAIFQTTKPITCSSSTLPTSSVVTITSQSSTPLVTSSTVASMQQAQTQGTQIHQHQQLISATIAGGSQQQQQQQQLGLPSLTPTTPSPTTNPILAMTSMMNATVGHLSTAPP--VSVSSTAVTPSSGQLVTLSSASSGGGAGFPATPTKETPSKGPTATLVPIDSPKTPVSGKDTCTTPKSSTPATVSASVEASSSTGEALSNGDASDRSSTPSKGATTPTSKQSNAAVQPPSSTIPNSVSGKEEPKLTTCGSLTSATSTSTTTTITNGIGVARTTASTAVSTASTTTTSSGTFTTSCTSTTTTTTSSISNGSKDLPKAMIKPNVLTHVIDGFIIQEANEPFPVTRQRYADKDVSDEPPKKKATMQEDIKLSGIASAP-------GSDMVACEQCGKMEHKAKLK-RKRYCSPGCSRQAKNGIGGVGSGETNGLGTGGIVGVDAMALVDRLDEAMAEEKMQTESYQTVSDALPIQAATPEVPPISMPVLAAMSTSSPLSLPLTLPLPIAIAPTVSLPVVSAGVVAPVLAIPSSNINGSDRPPISSWSVEEVSNFIRELPGCQDYVDDFIQQEIDGQALLLLKENHLVNAMGMKLGPALKIVAKVESIKEVPP-GDVKD----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39769-1", "uniprot_id": "PHP_DROME", "id": "P39769-1", "name": "Polyhomeotic-proximal chromatin protein", "aln": "MDR--RALKFMQKRADTESDTTTPVSTTASQGISASAILAGGTLPLKDNSNIREKPLHHNYNHNNNNSSQHSHSHQQQQQQQVGGKQLERPLKCLETLAQKAGITFDEKYDVASPPHPGIAQQQATSGTGPATGSGSVTPTSHRHGTPPTGRRQTHTPSTPNRPSAPSTPNTNCNSIARHTSLTLEKAQNPGQQVAATTTVPLQISPEQLQQFYASNPYAIQVKQEFPTHTTSGSGTELKHATNIMEVQQQLQLQQQLSEANGGGAASAGAGGAASPANSQQSQQQQHSTAISTMSPMQLAAATGGVGGDWTQGRTVQLMQPSTSFLYPQMIVSGNLLHPGGLGQQPIQVITAGKPFQGNGPQMLTTTTQNAKQMIGGQAGFAGGNYATCIPTNHNQSPQTVLFSPMNVIS--PQQQQNLLQSMAAAAQQQQLTQQQQQFNQQQQQQLTQQQQQ--LTAALAKVGVDAQGKLAQKVVQKVTTTSSAVQAATGPGSTGSTQTQQVQQVQQQQQQTTQTTQQCVQVSQSTLPVGVGGQSVQTAQLLNAGQAQQMQIPWFLQNAAGLQPFGPNQIILRNQPDGTQGMFIQQQPATQTLQTQQNQIIQCNVTQTPTKARTQLDALAPKQQQQQQQVGTTNQTQQQQLAVATAQLQQQQQQLTAAALQRPGAPVMPHNGTQVRPASSVSTQTAQNQSLLKAKMRNKQQPVRPALATLKTEIGQVAGQNKVVGHLTTVQQQQQATNLQQVVNAAGNKMVVMSTTGTPITLQNGQTLHAATAAGVDKQQQQLQLFQKQQILQQQQMLQQQIAAIQMQQQQAAVQAQQQQQQQVSQQQQVNAQQQQAVAQQQQAVAQAQQQQREQQQQVAQAQAQHQQALANATQQILQVAPNQFITSHQQQQQQQLHNQLIQQQLQQQAQAQVQAQVQAQAQQQQQQREQQQNIIQQIVVQQSGATSQQTSQQQQHHQSGQLQLSSVPFSVSSSTTPAGIA--TSSALQAALSASGAIFQTAKPGTCSSSS-PTSSVVTITNQSSTPLVTSSTVASIQQAQTQSAQVHQHQQLISATIAGGTQQQPQ----GPPSLTPTT-----NPILAMTSMMNATVGHLSTAPPVTVSVTSTAVTSSPGQLVLLSTASSGGGGSIPATPTKETPSKGPTATLVPIGSPKTPVSGKDTCTTPKSSTPATVSASVEASSSTGEALSNGDASDRSSTPSKGATTPTSKQSNAAVQPPSSTTPNSVSGKEEPKLATCGSLTSATSTSTTTTITNGIGVARTTASTAVSTASTTTTSSGTFITSCTSTTTTTTSSISNGSKDLPKAMIKPNVLTHVIDGFIIQEANEPFPVTRQRYADKDVSDEPPKKKATMQEDIKLSGIASAP-------GSDMVACEQCGKMEHKAKLK-RKRYCSPGCSRQAKNGIGGVGSGETNGLGTGGIVGVDAMALVDRLDEAMAEEKMQTEATPKLSESFPILGASTEVPPMSLPVQAAISAPSPLAMPLGSPLSVALPTLAPLSVVTSGAAP-----KSSEVNGTDRPPISSWSVDDVSNFIRELPGCQDYVDDFIQQEIDGQALLLLKEKHLVNAMGMKLGPALKIVAKVESIKEVPPPGEAKDPGAQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. .:* : :*. . . . .. *: . * *. * : : . ..:: * : : .: **:. : :. *** *... :.: .**: * * ::* *. ** : : .*. .**:: * .:::.. *:. *:: . .** . . :. : * :.* :*:. *.** **::. *. **.*:.. .*::. : :* * ** ****. .. . :*::.*.: *:*:: * : *: :* :** .. .:* ..* *. * **.::.: ..* . .* **:.. * : .*: :: :* : **. . ** :....* .: :: *:* * * :. : :****::* *** ::*** : ::*** * *.* ::: : :***** * ****:: *. : :: * **.*.* :.. *.*** * * **. * *.. . . .. * :** ... .. .:. : *...* :. ..*.: * . :*. : * :.. . * :.. ::. .**::: * .. *.: : .*: .. **.*: .. *.* * ::* * *.* *: .. *... : . . : .. * . *:.: * : * * : : . :...:. .:.. .. : . .:.*.. .* : .: . *... *:*::**::***:*:**:***. ***** .: .: . . : : *. . :. . :::: ** *** ::: **:** *::: : *.... * :..::** . : . . *: . . .: .:. ::. * .::: . : .. . . * ***::* :** .* ***: .::* .*************:**:.**.:******** **:: :**. ", "identical_positions": 235, "similar_positions": 364, "identity": "14.51%" }, { "cls_id": "homologset.agr.RGD:1309204", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K610-1", "uniprot_id": "A0A0G2K610_RAT", "id": "A0A0G2K610-1", "name": "", "aln": "----MNIHTKR-------------KIIKN-----------------------------------LTTLENRMLMFDGMPAVRVKTELLESEQGSPNVHNYPDMEAIPLLLNNVKGEPPEDSLPVDHFQTQTEPVDLSINKARTSPTAASSSPVSMTASASSPSSTSTSSSSSSRPASSPTVITSVSSASSSSTVLSPGPLVASASGMGGQQFLHIIHPVPPSSPMNLQSNKLSHVHRIPVVVQSVPVVYT-AVRSPGNVNNTIVVPLLEDGRSHGKAQMEPRGLSPRQSKSDSDDDDLPNVTLDSVNETGSTALSIARAVQEVHPSPVSRVRGNRMNNQKFACSISPFSIESTRRQRRSESPDSRKRRIHRCDFEGCNKVYTKSSHLKAHRRTHTGEKPYKCTWEGCTWKFARSDELTRHYRKHTGVKPFKCADCDRSFSRSDHLALHRRRHMLV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35738-1", "uniprot_id": "KLF12_MOUSE", "id": "O35738-1", "name": "Krueppel-like factor 12", "aln": "----MNIHMKR-------------KTIKN-----------------------------------LSALENRMLMLDGMPAVRVKTELVESEQGSPNVHNYPDMEAVPLLLNNVKGEPPEDSLPVDHFQTQTEPVDLSINKARTSPTAASSSPVSMTASASSPSSTSTSSSSSSRPASSPTVITSVSSASSSSTVLSPGPLVASASGVGGQQFLHIIHPVPPSSPMNLQSNKLSHVHRIPVVVQSVPVVYT-AVRSPGNVNNTIVVPLLEDGRSHGKAQMEPRGLSPRQSKSDSDDDDLPNVTLDSVNETGSTALSIARAVQEVHPSPVSRVRGNRMNNQKFACSISPFSIESTRRQRRSESPDSRKRRIHRCDFEGCNKVYTKSSHLKAHRRTHTGEKPYKCTWEGCTWKFARSDELTRHYRKHTGVKPFKCADCDRSFSRSDHLALHRRRHMLV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y4X4-1", "uniprot_id": "KLF12_HUMAN", "id": "Q9Y4X4-1", "name": "Krueppel-like factor 12", "aln": "----MNIHMKR-------------KTIKN-----------------------------------INTFENRMLMLDGMPAVRVKTELLESEQGSPNVHNYPDMEAVPLLLNNVKGEPPEDSLSVDHFQTQTEPVDLSINKARTSPTAVSSSPVSMTASASSPSSTSTSSSSSSRLASSPTVITSVSSASSSSTVLTPGPLVASASGVGGQQFLHIIHPVPPSSPMNLQSNKLSHVHRIPVVVQSVPVVYT-AVRSPGNVNNTIVVPLLEDGRGHGKAQMDPRGLSPRQSKSDSDDDDLPNVTLDSVNETGSTALSIARAVQEVHPSPVSRVRGNRMNNQKFPCSISPFSIESTRRQRRSESPDSRKRRIHRCDFEGCNKVYTKSSHLKAHRRTHTGEKPYKCTWEGCTWKFARSDELTRHYRKHTGVKPFKCADCDRSFSRSDHLALHRRRHMLV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GCU3-1", "uniprot_id": "A0AC58GCU3_DANRE", "id": "A0AC58GCU3-1", "name": "", "aln": "MFPGRNPYMAHPPTGTPDSSSALYKTCQDPLCARLGWVCGQSRTASSRCHYCWGNCHSCQRLQLGDAINNRMLMLDGMPAVRVKAEPLESERGSPKVHGYPDMEAVPLLLSKVKAEPPEDLLSSDQFQTQTEPVDLSINKTRTSSPLSNNSPVT---SAFSPSSSSSSSS-------SPSVIASVSSGMPS--VLTSGSLVGSSHGVRGQQFLHIIHPVPPSSPSKLP----SQVHRIPVVVQSLPLMYTTSVRSPSTLSSTIMLPLLDEARCQDKAQTDPNGLSPRQIKSDSDDDDLPNVTLDSVNETGSTALSIARAVQD---------------------SMSPFSIESIRRPPPPESPDSKKRRIHRCDFAGCNKVYTKSSHLKAHRRTHTGEKPYKCTWDGCTWKFARSDELTRHYRKHTGVKPFKCGDCDRSFSRSDHLALHRRRHMLV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : : * :: :::*****:*********:* :***:***:**.******:****.:**.***** *. *:**************:***.. ..***: ** ****:*:*** **:**:****. .* **:.*.**.*: *: **************** :* *:**********:*::** :****..:..**::***::.* :.*** :*.****** ********************************: *:******* ** .*****:********* *****************************:***************************.**********************", "identical_positions": 275, "similar_positions": 63, "identity": "60.44%" }, { "cls_id": "homologset.agr.RGD:1309205", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q7TQK0-1", "uniprot_id": "CCNT2_MOUSE", "id": "Q7TQK0-1", "name": "Cyclin-T2", "aln": "-------MASGRGASSR---------------------------WFFTREQLENTPSRRCGVEADEELSHRQQAAN-LIQDMGQRLNVSQLTINTAIVYMHRFYMHHSFTKFNRNIISPTALFLAAKVEEQARKLEHVIKVAHACLHPLEPLLDTKCDAYLQQTQELVLLETIMLQTLGFEITIE---HPHTDVVKCTQLVRASKDLAQTSYFMATNSLHLTTFCLQYKPTVIACVCIHLACKWSNWEIPVSTDGKHWWEYVDPTVTLELLDELTHEFLQILEKTPSRLKRIRN----------WRA--MAKKPKVDGQVSETPLLGSS-------LVQNSILVDSVTGVPANPSFQKPSTSTFPAPIPLNSGSTSVQDSRASDNLSVLAAGMPSTSYSLSSHQEWP------QHPDSARTDPVYT-------QKQEATLSGSQY-ISFQQGPSMALHSGLHHRPDKVADHSSAKQEYTHKAGSSKHHGPIPATPGMLPQKMSLD---------------KYREKRKLETLDVDTRDHYLAAHAEQQHKHGPAQAVTGTSVTSP---------IKMKLPLTNSDRPEKHVAEKKERSGSLKLRIPIPPPDKG-----PSKEELKMKIKVASSERHSSSDEGSGKSKHS------SPHISRDHKEKHKEHPANRHHSS-------------HKYLHMHSG----GSKHTADGMPPTVLRSPVG------------LGPEGVSSASS-ARKKLHSSEASHNHHSKMSKSSKSAGSSSSSSS-VKQYLSSHS---------------------------------------SVFNHPLPPPPPVTYQVGYGHLSTLVK----LDKKPVEPHGPEANHEYSTSSQHMDYKDTFDMLDSLLSAQGMNM------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZGL6-1", "uniprot_id": "D3ZGL6_RAT", "id": "D3ZGL6-1", "name": "", "aln": "-------MASGRGASSR---------------------------WFFTREQLENTPSRRCGVEADEELSHRQQAAN-LIQDMGQRLNVSQLTINTAIVYMHRFYMHHSFTKFNRNIISPTALFLAAKVEEQARKLEHVIKVAHACLHPLEPLLDTKCDAYLQQTQELVLLETIMLQTLGFEITIE---HPHTDVVKCTQLVRASKDLAQTSYFMATNSLHLTTFCLQYKPTVIACVCIHLACKWSNWEIPVSTDGKHWWEYVDPTVTLELLDELTHEFLQILEKTPSRLKRIRN----------WRA--MAKKPKVDGQVSETPLLGSS-------LVQNSILVDSVTGVPANPSFQKPSTSTFPAPLPLTSGSTSVQDGRASDTGSVLAG-MPSSSYTVSSHQEWP------HHPDSARTDPVYT-------QKQEATLSGSQY-LSFQQGPSMALHSGLHHRPDKVADHSSAKQEYTHKGGSSKHHGPIPATPGVVPQKMSLD---------------KYREKRKLETLDLDSRDHYMAAHAEQQHKHGPAQAVAGTSVTSP---------IKMKLPLTNSDKPEKHLAEKRERSGSLKLRIPIPPPDKG-----PSKEELKMKIKVSSSERHSSSDEGSGKSKHS------SPHISRDHKEKHKEHPANRHHSS-------------HKHLHMHSS----GGSKHADGMPPTVLRSPVG------------LGPEGISSGPS-ARKKLHINDASHNHHSKMSKSSKSSGSSSSSSS-VKQYLSSHS---------------------------------------SVFNHPLPPPPPVTYQVGYGHLSTLVK----LDKKPVEPHGPEANHEYSTSSQHMDYKDTFDMLDSLLSAQGMNM------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O60583-1", "uniprot_id": "CCNT2_HUMAN", "id": "O60583-1", "name": "Cyclin-T2", "aln": "-------MASGRGASSR---------------------------WFFTREQLENTPSRRCGVEADKELSCRQQAAN-LIQEMGQRLNVSQLTINTAIVYMHRFYMHHSFTKFNKNIISSTALFLAAKVEEQARKLEHVIKVAHACLHPLEPLLDTKCDAYLQQTQELVILETIMLQTLGFEITIE---HPHTDVVKCTQLVRASKDLAQTSYFMATNSLHLTTFCLQYKPTVIACVCIHLACKWSNWEIPVSTDGKHWWEYVDPTVTLELLDELTHEFLQILEKTPNRLKKIRN----------WRANQAARKPKVDGQVSETPLLGSS-------LVQNSILVDSVTGVPTNPSFQKPSTSAFPAPVPLNSGNISVQDSHTSDNLSMLATGMPSTSYGLSSHQEWP------QHQDSARTEQLYS-------QKQETSLSGSQYNINFQQGPSISLHSGLHHRPDKISDHSSVKQEYTHKAGSSKHHGPISTTPGIIPQKMSLD---------------KYREKRKLETLDLDVRDHYIAAQVEQQHKQGQSQAASSSSVTSP---------IKMKIPIAN---TEKYMADKKEKSGSLKLRIPIPPTDKS-----ASKEELKMKIKVSSSERHSSSDEGSGKSKHS------SPHISRDHKEKHKEHPSSRHHTSS------------HKHSHSHSGSSSGGSKHSADGIPPTVLRSPVG------------LSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGSSSSSSSSVKQYISSHN---------------------------------------SVFNHPLPPPPPVTYQVGYGHLSTLVK----LDKKPVETNGPDANHEYSTSSQHMDYKDTFDMLDSLLSAQGMNM------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O96433-1", "uniprot_id": "CCNT_DROME", "id": "O96433-1", "name": "Cyclin-T", "aln": "MSLLATPMPQAATASSSSSASAAASASGIPITANNNLPFEKDKIWYFSNDQLANSPSRRCGIKGDDELQYRQMTAY-LIQEMGQRLQVSQLCINTAIVYMHRFYAFHSFTHFHRNSMASASLFLAAKVEEQPRKLEHVIRAANKCLPP------TTEQNYAELAQELVFNENVLLQTLGFDVAID---HPHTHVVRTCQLVKACKDLAQTSYFLASNSLHLTSMCLQYRPTVVACFCIYLACKWSRWEIPQSTEGKHWFYYVDKTVSLDLLKQLTDEFIAIYEKSPARLKSKLNSIKAIAQGASNRTANSKDKPKEDWKITEMMKGYHSNITTPPELLNGNDSRDRDRDRERERERERDPSSLLPPPAMVPQQRRQDGGHQRSSSVSGVPGSSSSSSSSSHKMPNYPGGMPPDAHTDHKSKQPGYNNRMPSSHQRSSSSGLGSSGSGSQRSSSSSSSSSQQPGRPSMPVDYHKSSRGMPPVGVGMPPHGSHKMTSGSKPQQPQQQPVPHPSASNSSASGMSSKDKSQSNKMYPNAPPPYSNSAPQNPLMSRGGYPGASNGSQPPPPAGYGGHRSKSGSTVHGMPPFEQQLPYSQSQSYGHMQQQPVPQSQQQQMPPEASQHSLQSKNSLFSPEWPDIKKEPMSQSQPQPFNGLLPPPAPPGHDYKLNSHPRDKESPKKERLTPTKKDKHRPVMPPVGSGNSSSGSGSSKPMLPPHKKQIPHGGDLLTNPGESGSLKRPNEISGSQYGLNKLDEIDNSNMPREKLRKLDTTTGLPTYPNYEEKHTPLNMSNGIETTPDLVRSLLKESLCPSNASLLKPDALTMPGLKPPAELLEPMPAPATIKKEQGITPMTSLASGPAPMDLEVPTKQAGEIKEESSSKSEKKKKKDKHKHKEKDKSKDKTEKEERKKHKKDKQKDRSGSGGSKDSSLPNEPLKMVIKNPNGSLQAGASAPIKLKISKNKVEPNNYSAAAGLPGAIGYGLPPTTATTTSASIGAAAPVLPPYGAGGGGYSSSGGSSSGGSSKKKHSDRDRDKESKKNKSQDYAKYNGAGGGIFNPLGGAGAAPNMSGGMGAPMSTAVPPSMLLAPTGAVPPSAAGLAPPPMPVYNKK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P46962-1", "uniprot_id": "CTK2_YEAST", "id": "P46962-1", "name": "CTD kinase subunit beta", "aln": "---MPSTFESQLFFSRP----------------------------FLSKRQIQR--AQKNTISDYRNYNQKKLAVFKFLSDLCVQLKFPRKTLETAVYFYQRYHLFNRFETEVCYTVATSCLTLGCKEVETIKKTNDICTLSLRLRNVVK----INTDILENFKKRVFQIELRILESCSFDYRVNNYVHIDEYVIKIGRELSFDYKLCNLAWVIAYDALKLETILVIPQHSIALAI---LKIAYELLDNKNWSSKRYSLFETDEKSVNEAYFDIVNFYINSFDMCDLQRHLPAD---------------------------LLPIGVER-------FMELKKNAGPESGLPQIPDHLLN-----ADPYITITRDNNVQERRYVLSLELINGESSINSSTRHA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . * :::. *: . ::: :. : . :: :. ::.:: :*:..: ::**: : :*:: .: * ::.:.* *..* * :* :.: : . : : :.:. * :*:: .*: :: * . *:: : : .*.: ::.:* ::*:* :: : : :: .. * :. : :. :: .* . : ::.. :: : : : : ::: . . . . . * . : . . : . .* ", "identical_positions": 25, "similar_positions": 122, "identity": "2.26%" }, { "cls_id": "homologset.agr.RGD:1309207", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AXZ3-1", "uniprot_id": "P2R3C_RAT", "id": "Q6AXZ3-1", "name": "Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma", "aln": "------MDWKDVLRRRLASPNSDPKRKKSEQELKDEEMDLFTKYYSEWKGGRKNTNEFYKTIPRFYYRLPAEDEVLLQKLREESRAVFLQRKSRELLDNEELQNLWFLLDKHQIPPMIGEEAMINYENFLKVGEKAGPKCKQFFTAKVFAKLLHTDSYGRVSIMQFFNYVMRKVWLHQTRIGLSLYDVAGQGYLRESDLENYILELIPTLPQLDGLEKSFYSFYVCTAVRKFFFFLDPLRTGKIKIQDILACSFLDDLLELRDEELSKESQETNWFSAPSALRVYGQYLNLDKDHNGMLSKEELSRYGTATMTNVFLDRVFQECLTYDGEMDYKTYLDFVLALENRKEPAALQYIFKLLDIENKGYLNVFSLNYFFRAIQELMKIHGQDPVSFQDVKDEIFDMVKPKDPLKISLQDLINSNQGDTVTTILIDLNGFWTYENREALVANDNE-NSADLDDT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JK24-1", "uniprot_id": "P2R3C_MOUSE", "id": "Q9JK24-1", "name": "Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma", "aln": "------MDWKDVLRRRLASPNTDPKRKKSEQELKDEEMDLFTKYYSEWKGGRKNTNEFYKTIPRFYYRLPAEDEVLLQKLREESRAVFLQRKSRELLDNEELQNLWFLLDKHQIPPMIGEEAMINYENFLKVGEKAGPKCKQFFTAKVFAKLLHTDSYGRISIMQFFNYVMRKVWLHQTRIGLSLYDVAGQGYLRESDLENYILELIPTLPQLDGLEKSFYSFYVCTAVRKFFFFLDPLRTGKIKIQDILACSFLDDLLELRDEELSKESQETNWFSAPSALRVYGQYLNLDKDHNGMLSKEELSRYGTATMTNVFLDRVFQECLTYDGEMDYKTYLDFVLALENRKEPAALQYIFKLLDIENKGYLNVFSLNYFFRAIQELMKIHGQDPVSFQDVKDEIFDMVKPKDPLKISLQDLINSNQGDTVTTILIDLNGFWTYENREALVANDNE-NSADLDDT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q969Q6-1", "uniprot_id": "P2R3C_HUMAN", "id": "Q969Q6-1", "name": "Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma", "aln": "------MDWKEVLRRRLATPNTCPNKKKSEQELKDEEMDLFTKYYSEWKGGRKNTNEFYKTIPRFYYRLPAEDEVLLQKLREESRAVFLQRKSRELLDNEELQNLWFLLDKHQTPPMIGEEAMINYENFLKVGEKAGAKCKQFFTAKVFAKLLHTDSYGRISIMQFFNYVMRKVWLHQTRIGLSLYDVAGQGYLRESDLENYILELIPTLPQLDGLEKSFYSFYVCTAVRKFFFFLDPLRTGKIKIQDILACSFLDDLLELRDEELSKESQETNWFSAPSALRVYGQYLNLDKDHNGMLSKEELSRYGTATMTNVFLDRVFQECLTYDGEMDYKTYLDFVLALENRKEPAALQYIFKLLDIENKGYLNVFSLNYFFRAIQELMKIHGQDPVSFQDVKDEIFDMVKPKDPLKISLQDLINSNQGDTVTTILIDLNGFWTYENREALVANDSE-NSADLDDT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q803V3-1", "uniprot_id": "P2R3C_DANRE", "id": "Q803V3-1", "name": "Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma", "aln": "MANDITAHWKDLLRKRLASLKPD---GRTEEEKKAEESELFSKYYTEWKGGEKGEDDSFKHIPRFYYRLPAEDEVLMQKLREESRAVFLQRKSRELLDNEELQNLWFLLDKHQVPPTTGDEAMISYESFLKVGEKAGTKCKLFFTARVYAKLLHNDPYGRISIMQFFNYVMRKVWLHQTRIGLSLYDVAGQGYLRESDLENYILELIPTLPQLDGLEKSFYSFYVCTAVRKFFFFLDPLHTGKIKIQDILACSFLDDLLELRDEELSKESQESNWFSAPSALRVYGQYLNLDKDHNGMLSKEELSRYGTGTLTSVFLDRVYQACLTYDGEMDYKTYLDFVLALENRKEPAALQYIFKLLDMENKGYLNVFALNYFFRAIQEQMKIHGQEPVSFQDVKDEIFDMVKPKDPYKITLQDLVNSGQGDTVSSILIDLNGFWTYENREVLVANDTDSNAADLDDT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .**::**:***: :. ::*:* * ** :**:***:*****.*. :: :* ***************:************************************ ** *:****.**.*********.*** ****:*:*****.*.***:******************************************************************************:********************************:************************************.*:*.******:* *************************************:*********:********** ******:******************** **:****:**.*****::***************.*****.: *:******", "identical_positions": 387, "similar_positions": 46, "identity": "84.13%" }, { "cls_id": "homologset.agr.RGD:1309209", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4A5E4-1", "uniprot_id": "D4A5E4_RAT", "id": "D4A5E4-1", "name": "Cyclin-I", "aln": "MKFPGPLENQRLSSLLERAISREAQMWKVN---VPKIPTNQNVSPSQRDEVIQWLAKLKYQFN---LYPETFALASSLLD--RFLATVKAHPKYLN--------CIAISCFFLAAKTVEEDEKIPVLKVLARDSFCGCSSSEILR----MERIILDKLN--WDLHTATPLDFLHIFHAIAVSTRPQLLFSLPRLSPSQHLAVLTK------------------------QLLHCMACNQLLQ-------FKGSMLALAMVSLEMEKLIPD---------------WLPLTIELLQKAQMDSSQLIHCRELVAYHLSALQSS--------LPLNSVYVYRPLKHTLVTCDKGAFKLHPSSIS---GPDFSKDNSKPEVPVRGPAAFHLHLPAVSG---CKHTSAKRKVEEME--------------------------------------------------------------------------VDDLYDG------------------IKRLYNEDSGSENVGSVCG--------------TDLSRQEGHASPCPPLQPVSVM-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z2V9-1", "uniprot_id": "CCNI_MOUSE", "id": "Q9Z2V9-1", "name": "Cyclin-I", "aln": "MKFPGPLENQRLSSLLERAISREAQMWKVN---VPKIPTNQNVSPSQRDEVIQWLAKLKYQFN---LYPETFALASSLLD--RFLATVKAHPKYLN--------CIAISCFFLAAKTVEEDEKIPVLKVLARDSFCGCSSSEILR----MERIILDKLN--WDLHTATPLDFLHIFHAIAVSARPQLLFSLPKLSPSQHLAVLTK------------------------QLLHCMACNQLLQ-------FKGSMLALAMVSLEMEKLIPD---------------WLPLTIELLQKAQMDSSQLIHCRELVAYHLSALQSA--------LPLNSVYVYRPLKHTLVTCDKGAFKLHPSSVS---GPDFSKDNSKPEVPVRGPAAFHLHLPAASG---CKQTSAKRKVEEME--------------------------------------------------------------------------VDDFYDG------------------IKRLYNEDNGPENVGSVCG--------------TDLSRQEGHASPCPPLQPVSVM-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14094-1", "uniprot_id": "CCNI_HUMAN", "id": "Q14094-1", "name": "Cyclin-I", "aln": "MKFPGPLENQRLSFLLEKAITREAQMWKVN---VRKMPSNQNVSPSQRDEVIQWLAKLKYQFN---LYPETFALASSLLD--RFLATVKAHPKYLS--------CIAISCFFLAAKTVEEDERIPVLKVLARDSFCGCSSSEILR----MERIILDKLN--WDLHTATPLDFLHIFHAIAVSTRPQLLFSLPKLSPSQHLAVLTK------------------------QLLHCMACNQLLQ-------FRGSMLALAMVSLEMEKLIPD---------------WLSLTIELLQKAQMDSSQLIHCRELVAHHLSTLQSS--------LPLNSVYVYRPLKHTLVTCDKGVFRLHPSSVP---GPDFSKDNSKPEVPVRGTAAFYHHLPAASG---CKQTSTKRKVEEME--------------------------------------------------------------------------VDDFYDG------------------IKRLYNEDNVSENVGSVCG--------------TDLSRQEGHASPCPPLQPVSVM-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q95TJ9-1", "uniprot_id": "CYCG_DROME", "id": "Q95TJ9-1", "name": "Cyclin G", "aln": "MSVPVRYSSAAAEYAAEVDCELESTLQQQQQLHLQQQYEQYQHYQYQREQDIAYYCQLQAARQQEQLMQQRTSMSSSVMPGLALPQDHQDHPAALLNGPHNNNIGLAMDAHSINAILVDDEQPSTSAQAAAAAAASAGGSAGAGSGSGLGGAIGGGKLANGINRNAEMPTDWMRIADEGRYGTPGAAGLEYQKYEQQQQLEDLAESEAGAVGGASNNNGESSSSLKKLEDQLHALTSDELYETLKEYDVLQDKFHTVLLLPKESRREVTAGGRDGSAYVLRCLKMWYELPSDVLFSAMSLVDRFLDRMAVKPKHMACMSVASFHLAIKQLDLKPIPAEDLVTISQCGCTAGDLERMAGVIANKLGVQMGHAPITSVSYLRIYYALFRNLAKEIGGDFFKFYQQLIKLEELENRLEILMCDVKTTVITPSTLALVLICLHLDFHIKESYTRGSPELKHVFEYILFLQQYMRIPDRVFTCGFSIVSGILSHYNGQNKAPYKQRLVWKLSSRTLRVLRPINRFSSDLPTIEEGIPNALDDGLRSRTESISSEEEEDWPTSPIIPIFEQC", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*..* .. . * *: : : : : : : : **:: * : .:*: : * : :::**:: : : ** * :*:... : * *:::: . :. * : .. .*: * .** : :: * *:::* . .: :. : . .*:* *:: : **.::.::* : ::..: :: ::. * .: :. * *. ::* .* .:::. : . *:: :. : * *:.: . :. : * * :. .. :. * ::.: .. :* *:. :*. * * . *:**:* : . *:* :: * : ..:: :: .:* :* . * .*: *: ", "identical_positions": 59, "similar_positions": 148, "identity": "10.42%" }, { "cls_id": "homologset.agr.RGD:1309210", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D3N8-1", "uniprot_id": "GRTP1_MOUSE", "id": "Q9D3N8-1", "name": "Growth hormone-regulated TBC protein 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------MDPAERA-------------QAARARVPRIDPYGFER-PEDFDYAAYEEFFSTYLVILTKRAIKWSKLLKGNGGVRK----------SVTVKRYVRKGIPLEHRARVWMAVSGAQARMDQSPGYYHRLLEGE-SSSSLD---------EAIRTDLNRTFPDNVMFRKTAD----PCLQKTLYNVLLAYGLHNPDVGYCQCCAQKPGSSAGLRSSLTGMNFIAGYLILITKNEEESFWLLDALVGRILPDYYSPAMLGLKTDQEVLAELVRMKLPAVAALMDG------------------------------HGVLWTLLVSRWFICLFVDILPVETVLRIWDCLFNEGSKIIFRVALTLIKQHQEFILEASSIP---------------------------------DICDKFKQ-ITKGDFVTECHAFMQKIFSEPGSLSMTTITRLRKSCRAALQAQS---------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4QQU7-1", "uniprot_id": "GRTP1_RAT", "id": "Q4QQU7-1", "name": "Growth hormone-regulated TBC protein 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------MDPAERA-------------QAARARVPRIDPYGFER-PEDFDYAAYEEFFSTYLVILTKRAIKWSKLLKGSGGVRK----------SVT---------------------------------------------------------------DLNRTFPDNVMFRKTAD----PCLQKTLYNVLLAYGLHNQDVGYCQ-----------------GMNFIAGYLILITKNEEESFWLLDALVGRILPDYYSPAMLGLKTDQEVLAELVRMKLPAVAALMDG------------------------------HGVLWTLLVSRWFICLFVDILPVETVLRIWDCLFNEGSKIIFRVALTLIKQHQEFILEASSVP---------------------------------DICDKFKQ-ITKGDFVTECHTFMQKIFSEPGSLSMATITRLRESCRAALQAQS---------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5TC63-1", "uniprot_id": "GRTP1_HUMAN", "id": "Q5TC63-1", "name": "Growth hormone-regulated TBC protein 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------MQPAE------------------RSRVPRIDPYGFER-PEDFDDAAYEKFFSSYLVTLTRRAIKWSRLLQG-GGVPR----------SRTVKRYVRKGVPLEHRARVWMVLSGAQAQMDQNPGYYHQLLQGE-RNPRLE---------DAIRTDLNRTFPDNVKFRKTTD----PCLQRTLYNVLLAYGHHNQGVGYCQ-----------------GMNFIAGYLILITNNEEESFWLLDALVGRILPDYYSPAMLGLKTDQEVLGELVRAKLPAVGALMER------------------------------LGVLWTLLVSRWFICLFVDILPVETVLRIWDCLFNEGSKIIFRVALTLIKQHQELILEATSVP---------------------------------DICDKFKQ-ITKGSFVMECHTFMQKIFSEPGSLSMATVAKLRESCRARLLAQG---------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PBU5-1", "uniprot_id": "GRT1A_DANRE", "id": "Q6PBU5-1", "name": "Growth hormone-regulated TBC protein 1-A", "aln": "---------------------------------------------------------------------------------------------------------------------------------------MEERDRTGRTGQPQHRINQPSTARERANSVDAYGFQR-SDDFDYETHEQLMSEYLAVLTRRSIRWAKLLQGRRRVDR----------NLKVKRYVRKGVPNEHRPLVWMVCSGAQEQMDRNPGYYQSLLDTH-HEPKLE---------ESIRTDLHRTFPDNIYFRKSAE----PCLQQALYNVLVAYGHHNKAVGYCQ-----------------GMNFIAGYLILVSKDEETSFWLMEALLSRILPDYYTPAMLGLKTDQEVLGELVRLKAPAVWKLMQD------------------------------QGVMWTLVVSRWFICLFIDVLPVETVLRIWDCLFYEGSKILFRVALTLIRHHQQEIAEAQNLP---------------------------------DVCERFKR-ITRGAFVEDCHTFMQKIFQEPGSLSMATVSKLRESCRARIIADES--------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VEY4-1", "uniprot_id": "Q9VEY4_DROME", "id": "Q9VEY4-1", "name": "Growth hormone-regulated TBC protein 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------MDATASS------------------KFSDVDEYGFKR-GDHFDYNNYSKFMDGYLKTLTRRRMKWEAILQQNTDLTQV---------DAKLKRYIRKGIPGPYRPDVWMKISGAAAAQRRSPDLFRNLLRTEPFDKEIS---------DSISIDLPRTFPDNIHFDMK---------KQRLYNILIAYAHHNRDVGYCQ-----------------GLNYIAGLLLIVTDDEEKSFWLLKHIVENIVPQYHSHNMANLLRDLAVFRELVIRRIPAVNRHVDN------------------------------LGLPYPVIASKWFICIFAEVLPVETVLRIWDCVFAEGYKIVFRAALTMFVTHKNAILGCDDIA---------------------------------ALANLFRDTMIQDNIVTDCHGFVEAMFSLR--LKRSELESLRK---VAVLNPA---------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P48566-1", "uniprot_id": "GYP3_YEAST", "id": "P48566-1", "name": "GTPase-activating protein GYP3", "aln": "MQNDQQRFSLQNRTVLAHPYKRLGGAFTVKSPSVPNFHDKMHSDHSSSDSALVNGSFRANDHRSVEPSCLGQASPSEHDGNLSVIDLYGDEVESQRAEGEDDDDNNGDNGNEDLEEVHSDDLDLVPDDDNRQRVELEGAASATS----------ANSNGINNTHFDRYGFKKQNNYISEAEYDKWWVEYSQYCVRRKHKWQLLLEKSGLPVTDDSPSRFPSKSERLKRYVRKGIPAEWRGNAWWHFARGQEKLNKNKGVYSQLLRKMKQIKKQNPNEKQVQDLDIIERDLNRTFPDNIHFQSSLHNKEGPPIIKSLRRVLVAFSLYNPKIGYCQ-----------------SMNFLAGLLLLFLD-EERAFWMLVIITSRYLPGVHNINLEGVNIDQGVLMLCVKEYIPEVWSYIKPSIDHHQKNNKTFSPSNKKVLFNMQKNEFLYRLPPITLCTASWFMSCFVGVVPIETTLRIWDCLFYEESHFLFKVSLAVLKLSEHDLSKIKPR---NNSLNYSWGSNLNQ-------RGGSMGQEDSDMEIFQVIQTFPKTLLNPNEIFEKIIFKRRFNLNRLDQDEIDRCRKFVAAQRLKFKTYGELLGNSTSEADLPINDNTDNKGIHITSDAVNEALSSEVYGFKKSLAGVHWNNSIKEKVKQMRKKKDKGD", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q12317-1", "uniprot_id": "MSB4_YEAST", "id": "Q12317-1", "name": "GTPase-activating protein MSB4", "aln": "---------------------------------------MIMSSTMSTEAALVP-------NESVFDTVS---SFNEDDANYSVLDLY------------DDDDEGDDSSTVERKEILTTR-------------ELEKAKAFTS----------LIMADPEN--FDRYGFSKKGYFISQEEYDKWWTEYNRYTERRKKKWENFLLKNKIELHNDNPLVYPARTDELSKFVRKGIPAEWRGNAWWYFAGGQRQLDANVGVYDRLKSDCREGAVSG------KDMEAIERDLYRTFPDNIHFHKESFQNGEPAIIRSLRRVLMAFSVYDKTIGYCQ-----------------SMNFLVGLLLLFME-EEKAFWMLVIITGKYLPGVYESDLEGANVDQGVLVLCIKEYLPEIWSHIESSYMNGNGSTDQISGP-------ASGEEYLCRLPTLTLCTASWFMSCFVGVVPIETTLRIWDCLFYEESHFLFKVALGILKLSESEFLESKSQKLFRQYSSYTFGGSNDSDSTFKRLKNKIKTQEEADMEILQVIQNFPKRLLNPNDIFEKVLMKKKVALNGITQEKIDRGREYVAMARNRQRAS--------------------------------------------------------SRPKERRK------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: . .* ***.: :. :.: * :* :* :* ** ******: * : * .:*:*:. :: :**** .:*::.* *::. . ** :**:: : . :* : : . * *: : * : :. .: .: **:. * ::*:**.******:* * :::*:.:* :: : : : :: . * : ::. *. : . ", "identical_positions": 53, "similar_positions": 79, "identity": "7.9%" }, { "cls_id": "homologset.agr.RGD:1309211", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZKD4-1", "uniprot_id": "D3ZKD4_RAT", "id": "D3ZKD4-1", "name": "DNA replication factor Cdt1", "aln": "MAQSRVTDFYACRRPG-LAIPRAKSTCLTPSPG--GLVAPEFTRSSSRKRVRPHAEPGSDQPAPPARRRLRLPGLDSCPSFPADPSSPADPSSPADPSSSVCP-SPVCPSPVKRTKSTTVSRG--PQQSKVPSQDSISELQSCLRQARKLGAQARALRARVQENVVEPSTPDTKEPTEQPCVDKAPAYQRFHALAQPGLPGLVLPYKYQVLAEMFRSMDTIVSMLHNRSETVTFAKVKQGVQEMIRKRFEERNMGQIKTVYPESYSFRQECNVPTFKDSIKRSDYQLTIEPLLGQEAGGAT-QLTATGLLQRRQVFRQNLVERVKEHHKVFLASLNPPMTVPEDQLTRWHPRFNVDEVPDIEPAELPQPPVTEKLTTAQEVLARARNLMTPKMEKALSNLALRSAEPGSPGTSSPALPATPPATPPAASPSALKGVSQALLERIRAKEVQKQLARMTRCPEKELRLQRLERLPELARVLRGVFVSERKPALTMEVVCARMVDSSRAALSPGEMEKHLLLLAELLPDWLSLHRVRTDTYVKLDKAADLAGLTAKLARQVHAEG-L", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R4E9-1", "uniprot_id": "CDT1_MOUSE", "id": "Q8R4E9-1", "name": "DNA replication factor Cdt1", "aln": "MAQSRVTDFYACRRPG-LTTPRAKSICLTPSPG--GLVAPAFTRSSSRKRARPPAEPGSDQPAPLARRRLRLPGLDSCPSSLPEPSSPAEPSPPADPSPPADPGSPVCPSPVKRTKSTTVYVG--QQPGKIPSEDSVSELQSCLRRARKLGAQARALRARVQENAVEPSTPDAKVPTEQPCVEKAPAYQRFHALAQPGLPGLVLPYKYQVLVEMFRSMDTIVSMLHNRSETVTFAKVKQGVQEMMRKRFEERNVGQIKTVYPTSYRFRQECNVPTFKDSIKRSDYQLTIEPLLGQEAGGAT-QLTATCLLQRRQVFRQNLVERVKEQHKVFLASLNPPMAVPDDQLTRWHPRFNVDEVPDIEPAELPQPPVTEKLTTAQEVLARARSLMTPKMEKALSNLALRSAEPGSPGTSTPPLPATPPATPPAASPSALKGVSQALLERIRAKEVQKQLARMTRCPEQELRLQRLERLPELARVLRNVFVSERKPALTMEVVCARMVDSCQTALSPGEMEKHLVLLAELLPDWLSLHRIRTDTYVKLDKAVDLAGLTARLAHHVHAEG-L", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H211-1", "uniprot_id": "CDT1_HUMAN", "id": "Q9H211-1", "name": "DNA replication factor Cdt1", "aln": "MEQRRVTDFFARRRPGPPRIAPPKLACRTPSPARPALRAPASATSGSRKRARPPAAPGRDQARPPARRRLRLS--------VDEVSSPSTPEAPD---------IPACPSPGQKIKKSTPAAGQPPHLTSAQDQDTISELASCLQRARELGARVRALKASAQD-AGESCTPEAEGRPEEPCGEKAPAYQRFHALAQPGLPGLVLPYKYQVLAEMFRSMDTIVGMLHNRSETPTFAKVQRGVQDMMRRRFEECNVGQIKTVYPASYRFRQERSVPTFKDGTRRSDYQLTIEPLLEQEADGAAPQLTASRLLQRRQIFSQKLVEHVKEHHKAFLASLSPAMVVPEDQLTRWHPRFNVDEVPDIEPAALPQPPATEKLTTAQEVLARARNLISPRMEKALSQLALRSAAPSSPGSPRPALPATPPATPPAASPSALKGVSQDLLERIRAKEAQKQLAQMTRCPEQEQRLQRLERLPELARVLRSVFVSERKPALSMEVACARMVGSCCTIMSPGEMEKHLLLLSELLPDWLSLHRIRTDTYVKLDKAADLAHITARLAHQTRAEEGL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * *****:* **** . .* * ****. .* ** : *.****.** * ** **. * *******. : ***: *..* *.**** :: *.:* * : . .:*::*** ***::**:***:.***:* .*: . *..**::: .*:** :****************************.**********.******** *****::***:*:*:**** *:******** ** **** .******. :************ ***.**: ****: ******:* *:***:***:**.*****.*.*.**:********************* *****.***************.*::*:******:****** *.***:. *.********************** *********.*****:******:* ****************.**********:***.*****.*. : :*********:**:***********:***********.*** :**:**::.:** *", "identical_positions": 385, "similar_positions": 95, "identity": "68.26%" }, { "cls_id": "homologset.agr.RGD:1309212", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5BJS7-1", "uniprot_id": "CPNE9_RAT", "id": "Q5BJS7-1", "name": "Copine-9", "aln": "MSLGGASERSVPATKIEITVSCRNLLDLDTFSKSDPMVVLHTQSRASQEWREFGRTEVIDNTLNPDFVRKFVLDYFFEEKQNLRFDVYNVDSKANISKPKDFLGQAFLALGEVIGGQGSRVERPLTGVPGKKCGTILLTAEELSNCRDIATMQLCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVVKNTLNPVWQPFSIPVRALCNGDYDRTVKIDVYDWDRDGSHDFIGEFTTSYRELSKAQNQFTVYEVLNPRKKCKKKKYTNSGTVTLLSFSVDSEFTFVDYIKGGTQLNFTVAIDFTASNGNPLQPTSLHYMSPYQLSAYAMALKAVGEIIQDYDSDKLFPAYGFGAKLPPEGRISHQFPLNNNDEDPNCAGIEGVLESYFQSLRTVQLYGPTYFAPVINQVARAAAKISDGSQYYVLLIITDGVISDMTQTKEAIVSASSLPMSIIIVGVGPAMFEAMEELDGDDVRVSSRGRYAERDIVQFVPFRDYVDRSGNQVLSMARLAKDVLAEIPEQLLSYMRTRDIQPRPPPPANPNPTSAPEQP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q1RLL3-1", "uniprot_id": "CPNE9_MOUSE", "id": "Q1RLL3-1", "name": "Copine-9", "aln": "MSLSGASERSVPATKIEITVSCRNLLDLDTFSKSDPMVVLHTQSRASQEWREFGRTEVIDNTLNPDFVRKFVLDYFFEEKQNLRFDVYNVDSKANISKPKDFLGQAFLALGEVIGGQGSRVERPLTGVPGKKCGTILLTAEELSNCRDIATMQLCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVVKNTLNPVWQPFSIPVRALCNGDYDRTVKIDVYDWDRDGSHDFIGEFTTSYRELSKAQNQFTVYEVLNPRKKCKKKKYTNSGTVTLLSFSVDSEFTFVDYIKGGTQLNFTVAIDFTASNGNPLQPTSLHYMSPYQLSAYAMALKAVGEIIQDYDSDKLFPAYGFGAKLPPEGRISHQFPLNNNDEDPNCAGIEGVLESYFQSLRTVQLYGPTYFAPVINQVARAAAKISDGSQYYVLLIITDGVISDMTQTKEAIVSASSLPMSIIIVGVGPAMFEAMEELDGDDVRVSSRGRYAERDIVQFVPFRDYVDRSGNQVLSMARLAKDVLAEIPEQLLSYMRTRDIQPRPPPPVSPNPTPAPEQP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IYJ1-1", "uniprot_id": "CPNE9_HUMAN", "id": "Q8IYJ1-1", "name": "Copine-9", "aln": "MSLGGASERSVPATKIEITVSCRNLLDLDTFSKSDPMVVLYTQSRASQEWREFGRTEVIDNTLNPDFVRKFVLDYFFEEKQNLRFDVYNVDSKTNISKPKDFLGQAFLALGEVIGGQGSRVERTLTGVPGKKCGTILLTAEELSNCRDIATMQLCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVVKNTLNPVWQPFSIPVRALCNGDYDRTVKIDVYDWDRDGSHDFIGEFTTSYRELSKAQNQFTVYEVLNPRKKCKKKKYVNSGTVTLLSFSVDSEFTFVDYIKGGTQLNFTVAIDFTASNGNPLQPTSLHYMSPYQLSAYAMALKAVGEIIQDYDSDKLFPAYGFGAKLPPEGRISHQFPLNNNDEDPNCAGIEGVLESYFQSLRTVQLYGPTYFAPVINQVARAAAKISDGSQYYVLLIITDGVISDMTQTKEAIVSASSLPMSIIIVGVGPAMFEAMEELDGDDVRVSSRGRYAERDIVQFVPFRDYVDRSGNQVLSMARLAKDVLAEIPEQLLSYMRTRDIQPRPPPPANPSPIPAPEQP", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***.************************************:****************************************************:*****************************.*************************************************************************************************************************************************.*******************************************************************************************************************************************************************************************************************************************************************************..*.* .*****", "identical_positions": 543, "similar_positions": 9, "identity": "98.19%" }, { "cls_id": "homologset.agr.RGD:1309214", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R087-1", "uniprot_id": "B4GT7_MOUSE", "id": "Q8R087-1", "name": "Beta-1,4-galactosyltransferase 7", "aln": "MLPSRRKAAQLPWEDGR------------------------------------------------------ARLLPGGLRRKCSIFHLFIAFLLLVFFSLLWLQLSCSGDMAQVTRGQGQETSGPPRACPPEPPPEHWEEDESWGPHRLAVLVPFRERFEELLVFVPHMHRFLSRKRIQHHIYVLNQVDHFRFNRAALINVGFLESSNSTDYIAMHDVDLLPLNEELDYGFP-EAGPFHVASPELHPLYHYKTYVGGILLLSKQHYQLCNGMSNRFWGWGREDDEFYRRIKGAGLQLFRPSGITTG-YQTFRHLHDPAWRKRDQKRIAAQKQEQFKVDREGGLNTVKYRVDSRTALSIGGAPCTVLNVMLDCDKTATPWCIFG-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K4C0-1", "uniprot_id": "A0A0G2K4C0_RAT", "id": "A0A0G2K4C0-1", "name": "Beta-1,4-galactosyltransferase", "aln": "MLPSRRKAAQLPWEDGRRPFTHCSPCKSQSRSQKEPRVQEGICKGSRLVRPFAGLGSTTPQWKPSPQDSGGARLLPGGLRRKCSIFHLFIAFLLLVFFSLLWLQLSCSGDVAQVTRGQGQETSGPPRACPPEPPPEHWEEDESWGPHRLAVLVPFRERFEELLVFVPHMHRFLSRKKIQHHIYVLNQVDHFRFNRAALINVGFLESSNSTDYIAMHDVDLLPLNEELDYGFP-EAGPFHVASPELHPLYHYKTYVGGILLLSKQHYQLCNGMSNRFWGWGREDDEFYRRIKGAGLQLFRPLGITTG-YQTFRHLHDPAWRKRDQKRIAAQKQEQFKVDREGGLNTVRYRVDSRTALSVGGAPCTVLNVMLDCDKTATPWCTFG-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UBV7-1", "uniprot_id": "B4GT7_HUMAN", "id": "Q9UBV7-1", "name": "Beta-1,4-galactosyltransferase 7", "aln": "MFPSRRKAAQLPWEDGR------------------------------------------------------SGLLSGGLPRKCSVFHLFVACLSLGFFSLLWLQLSCSGDVARAVRGQGQETSGPPRACPPEPPPEHWEEDASWGPHRLAVLVPFRERFEELLVFVPHMRRFLSRKKIRHHIYVLNQVDHFRFNRAALINVGFLESSNSTDYIAMHDVDLLPLNEELDYGFP-EAGPFHVASPELHPLYHYKTYVGGILLLSKQHYRLCNGMSNRFWGWGREDDEFYRRIKGAGLQLFRPSGITTG-YKTFRHLHDPAWRKRDQKRIAAQKQEQFKVDREGGLNTVKYHVASRTALSVGGAPCTVLNIMLDCDKTATPWCTFS-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VBZ9-1", "uniprot_id": "B4GT7_DROME", "id": "Q9VBZ9-1", "name": "Beta-1,4-galactosyltransferase 7", "aln": "MVN----ISTINW------------------------------------------------------------VFVCGL----SFCLGGIAVLSLMPLGSDCVCP-LSNPLAKLAGG-GEGVSVIKKEPADEKQPQPHDHGAS--VHKMALLVPFRDRFEELLQFVPHMTAFLKRQGVAHHIFVLNQVDRFRFNRASLINVGFQFASDVYDYIAMHDVDLLPLNDNLLYEYPSSLGPLHIAGPKLHPKYHYDNFVGGILLVRREHFKQMNGMSNQYWGWGLEDDEFFVRIRDAGLQVTRPQNIKTGTNDTFSHIHNRYHRKRDTQKCFNQKEMTRKRDHKTGLDNVKYKILKVHEMLIDQVPVTILNILLDCDVNKTPWCDCSGTAAAASAVQT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. : : * :: ** *. :* * * :. : *. :*: . * *: .* : . * *: :.. * *::*:*****:****** ***** **.*: : ***:******:******:****** :*: **************::* * :* . **:*:*.*:*** ***..:******: ::*:: *****::**** *****: **:.****: ** .*.** .** *:*: **** :: **: * *:: **:.*:*:: . : :. .* *:**::**** . **** . ", "identical_positions": 147, "similar_positions": 81, "identity": "37.31%" }, { "cls_id": "homologset.agr.RGD:1309215", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P40329-1", "uniprot_id": "SYRC_RAT", "id": "P40329-1", "name": "Arginine--tRNA ligase, cytoplasmic", "aln": "MDGLVAQCSARLLQQEKEIKSLTAEIDRLKNCSYLEASPSLEQLREENLKLKYRLNILRRSLQAERKRP------TKNMININSRLQELFGCAIKAAYPDLENPPLVVTP--SQQPKFGDYQCNSAMGISQMLKAKEQKVSPREIAENITKHLPNNEYIDRVEIAGPGFINVHLRKDFVSEQLTNLLVNGVQLPVLGENEKVIVDFSSPNIAKEMHVGHLRSTIIGESMSRLFEFAGYNVLRLNHVGDWGTQFGMLIAHLQDKFPDYLTVSPPIGDLQAFYKESKKRFDTEEEFKKRAYECVVLLQSKNPDIMKAWNLICDVSREEFNKIYDALDITLIERGESFYQDRMKDIVKEFEDKGFVQVDDGRKIVFVPG--CSVPLTIVKSDGGYTYDTSDLAAIKQRLFEEKANKIIYVVDNGQATHFQTVFAAAQMIGWYDPKVTRVAHVGFGVVLGEDKKKFKTRSGETVRLMDLLEEGLRRSMDKLKEKERDKVLTEEELKAAQTSVAYGCIKYADLSHNRLNDYVFSFDKMLDDRGNTAAYLLYAFTRIRSIARLANIDEEMLQRAARETKIILDHEKEWKLGRCILRFPEILQKILDDLFLHTLCDYIYELATTFTEFYDSCYCVEKDRQTGKVLKVNMWRMLLCEAVAAVMAKGFDILGIKPVQRM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D0I9-1", "uniprot_id": "SYRC_MOUSE", "id": "Q9D0I9-1", "name": "Arginine--tRNA ligase, cytoplasmic", "aln": "MDGLVAQCSARLLQQEREIKALTAEIDRLKNCGCLEASPSLEQLREENLKLKYRLNILRRSLQEERRKP------TKNMININSRLQEVFGCAIRAAYPDLENPPLIVTP--SQQPKFGDYQCNSAMGISQMLKAKEQKVSPREIAENITKHLPNNKYIDKVEIAGPGFINVHLRKDFVSEQLTSLLVNGVQLPVLGDKEKVIVDFSSPNIAKEMHVGHLRSTIIGESMSRLFEFAGYDVLRLNHVGDWGTQFGMLIAHLQDKFPDYLTVSPPIGDLQAFYKESKKRFDADEEFKKRAYQCVVLLQSKNPDIMKAWNLICDVSREEFKKIYDALDITLIERGESFYQDRMKDIVKEFEDKGFVQVDDGRKIVFVPG--CSVPLTIVKSDGGYTYDTSDLAAIKQRLFEEKANKIIYVVDNGQAIHFQTIFAAAQMIGWYDPKVTLVTHVGFGVVLGEDKKKFKTRSGETVRLMDLLEEGLKRSMDKLKEKERDKVLTEEELKAAQTSVAYGCIKYADLSHNRLNDYIFSFDKMLDDRGNTAAYLLYAFTRIRSIARLANIDEAMLQRAARETKIILDHEKEWKLGRCILRFPEILQKILDDLFLHTLCDYIYELATTFTEFYDSCYCVEKDRQTGKVLKVNMWRMLLCEAVAAVMAKGFDILGIKPVQRM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P54136-1", "uniprot_id": "SYRC_HUMAN", "id": "P54136-1", "name": "Arginine--tRNA ligase, cytoplasmic", "aln": "MDVLVSECSARLLQQEEEIKSLTAEIDRLKNCGCLGASPNLEQLQEENLKLKYRLNILRKSLQAERNKP------TKNMINIISRLQEVFGHAIKAAYPDLENPPLLVTP--SQQAKFGDYQCNSAMGISQMLKTKEQKVNPREIAENITKHLPDNECIEKVEIAGPGFINVHLRKDFVSEQLTSLLVNGVQLPALGENKKVIVDFSSPNIAKEMHVGHLRSTIIGESISRLFEFAGYDVLRLNHVGDWGTQFGMLIAHLQDKFPDYLTVSPPIGDLQVFYKESKKRFDTEEEFKKRAYQCVVLLQGKNPDITKAWKLICDVSRQELNKIYDALDVSLIERGESFYQDRMNDIVKEFEDRGFVQVDDGRKIVFVPG--CSIPLTIVKSDGGYTYDTSDLAAIKQRLFEEKADMIIYVVDNGQSVHFQTIFAAAQMIGWYDPKVTRVFHAGFGVVLGEDKKKFKTRSGETVRLMDLLGEGLKRSMDKLKEKERDKVLTAEELNAAQTSVAYGCIKYADLSHNRLNDYIFSFDKMLDDRGNTAAYLLYAFTRIRSIARLANIDEEMLQKAARETKILLDHEKEWKLGRCILRFPEILQKILDDLFLHTLCDYIYELATAFTEFYDSCYCVEKDRQTGKILKVNMWRMLLCEAVAAVMAKGFDILGIKPVQRM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VXN4-1", "uniprot_id": "SYRC_DROME", "id": "Q9VXN4-1", "name": "Probable arginine--tRNA ligase, cytoplasmic", "aln": "MSELNMEL-KKLRELELKTQGLAARIQTAKSGEQLDVD--LVQLQIENKKLKNRLFILKKSIAEESTAAGGDVSKPKESSSITEHLESVFRQAIASAFPEFRDTPVIIAPVNSTSAKFGDYQCNNAMGLSKKLKEKGINKAPRDIATELKGHCPASPIIEKLEIAGAGFVNVFLSKDYASLALSNLLRNGVKPPEV-IKKRVLVDFSSPNIAKQMHVGHLRSTIIGESLCRLLEFLQHDVIRINHLGDWGTQFGMLIAHLEDRFPNYLNESPPISDLQLFYKESKKRFDEDEEFKKRAYSRVVSLQKGVPNSIKAWELICNVSRKEFQTIYERLDISVKERGESFYQSRMLSVVEYLRGKGLLEVDEGREIMWPDDTKTGIPLTIVKSDGGFTYDTSDMAAIRHRLEEELCDWIIYVVDSGQSTHFNTIFKAAERSAILNPLSHRVDHVQFGVVLGEDGKKFKTRSGDTVKLSDLLDEGMKRSLQQLESRGRDKVLTPQELKDAQESLAYGCIKYSDLCHNRISDYIFSFDKMLEDRGNTAVYLLYTYTRICSIARNSGEDFTNLPEILKKTNIVLDHEKEWKLAKTLLKLHDILIKCSKELFLHFLCEFCFEVCTVFTEFYDSCYCIEKNKQ-GDIIGVNHSRILLCEATAAVLRQCFYILGLKPVSKM", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. * : :* : * : :.*:*.*: *. * .. * **: ** *** ** **::*: * . .*: .* .:*:.:* ** :*:*::.:.*::::* * ..********.***:*: ** * : **:** ::. * * . *:::****.**:**.* **:.* *:.** ***: * : :::*:**********:**************:.**:** ::*:*:**:**************:*:**:**. ****.*** ********** :********. ** ** *: ***:***:***:*::.**: **::: ********.** .:*: :..:*:::**:**:*:: . .:**********:******:***::** ** .: ******.**: **:*:* **: . :* * *. ******** ********:**:* *** **::**:::*:.: ****** :**: ** *:*******:**.***:.**:*******:******.****::*** **** :. * * . ::*:*:*********.: :*:: :** * .:**** **:: :*:.*.**********:**::* *.:: ** *:*****.***: : * ***:***.:*", "identical_positions": 362, "similar_positions": 179, "identity": "54.03%" }, { "cls_id": "homologset.agr.RGD:1309216", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5RJQ7-1", "uniprot_id": "SDHF2_RAT", "id": "Q5RJQ7-1", "name": "Succinate dehydrogenase assembly factor 2, mitochondrial", "aln": "MAVVTLIPT--LARVLSKHSLLSPLLSVTSFRRFYRGDSPTD-----------SQKDMIEIPLPPWQERTDESIETKRARLLYESRKRGMLENCILLSLFAKEYLHNMTEKQLNLYDRLINEPSNDWDIYYWATE---AKPAPEIFEN-EVMELLREFTKNKNKEQRLRAPDLEYLFEKPR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C6I2-1", "uniprot_id": "SDHF2_MOUSE", "id": "Q8C6I2-1", "name": "Succinate dehydrogenase assembly factor 2, mitochondrial", "aln": "MAVVTLIPT--LARALSKHSLLSPLPSVTSFRRFYRGDSPTD-----------SQKDMIEIPLPPWQERTDESIETKRARLLYESRKRGMLENCILLSLFAKEYLHNMTEKQLNLYDRLINEPSNDWDIYYWATE---AKPAPEIFEN-EVMELLREFAKNKNKEQRLRAPDLEYLFEKPH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NX18-1", "uniprot_id": "SDHF2_HUMAN", "id": "Q9NX18-1", "name": "Succinate dehydrogenase assembly factor 2, mitochondrial", "aln": "MAVSTVFSTSSLMLALSRHSLLSPLLSVTSFRRFYRGDSPTD-----------SQKDMIEIPLPPWQERTDESIETKRARLLYESRKRGMLENCILLSLFAKEHLQHMTEKQLNLYDRLINEPSNDWDIYYWATE---AKPAPEIFEN-EVMALLRDFAKNKNKEQRLRAPDLEYLFEKPR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A3KP74-1", "uniprot_id": "SDHF2_DANRE", "id": "A3KP74-1", "name": "Succinate dehydrogenase assembly factor 2, mitochondrial", "aln": "MFSANIARK--VVCSVCRASLR-PTVCPVVYRG-YRGDAP--------------EPTILEIPLPPWQERAGEALDIKRKRLLYESRKRGMLENCILLSLFAKQYLNTMSESQLKQYDRLINEPSNDWDIYYWATD---TQPTPEVYQG-EVMDMLKEFTKNRDMEQRLDAPNLEYLDKSS-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q4V5I9-1", "uniprot_id": "SDF2A_DROME", "id": "Q4V5I9-1", "name": "Succinate dehydrogenase assembly factor 2-A, mitochondrial", "aln": "-----MLRQLRLTMDISGWIFLPWR---RSMSNMKDSPPPPPPLASTFNDVIVDYEDPDYLPLPEYPVRPNEPLETRKQRLLYQSRKRGMLENDLLLSTFAAKHLQNFSAEQTAQYDQLINGVSNDWDIYYWATE---VKPTPKEYDT-EIMGLLKEHVKNAERVTRLRQPDLNI------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1Z897-1", "uniprot_id": "SDF2B_DROME", "id": "A1Z897-1", "name": "Succinate dehydrogenase assembly factor 2-B, mitochondrial", "aln": "-----MLRQF-IVSTVGRRLQLPMMAQSRLASNLDKTEYTTP-------GEIVDYDDPPHLPVPEYPVRPDEPLETRKQRLLYQSRKRGMLENDLLLSTFVAKHLKDFNAEQTAEYDQLINGVSNDWDIFYWATD---TKPTPPQFDT-EIMRLLKEHVKNHEKVQRIRQPDL--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08230-1", "uniprot_id": "SDHF2_YEAST", "id": "Q08230-1", "name": "Succinate dehydrogenase assembly factor 2, mitochondrial", "aln": "--MHNMFPALTKTLSLQGYKIINSQTGSAAWSCGRRWFSSDK----------DDHDDVVTRIKIAPIKRTNEPLDKKRARLIYQSRKRGILETDLLLSGFAAKYLKKMNEEELEEYDSLLN--ELDWDIYYWATKNFKTSPLPDKWANSKLLKQLQEFSENKEKE-ILSMPDLSKYQ----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . *..*.:: :: **:*:*****:**. :*** *. ::*: :. .: ** *:* . ****:****. ..* * : ::: *::. :* : : *:* ", "identical_positions": 35, "similar_positions": 40, "identity": "19.34%" }, { "cls_id": "homologset.agr.RGD:1309217", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q0ZFS4-1", "uniprot_id": "Q0ZFS4_RAT", "id": "Q0ZFS4-1", "name": "Small ribosomal subunit protein mS33", "aln": "MPADPGILFLTAGEMSLSEYAVRMSRLSARIFGEVARPTDSKSMKVVNLFSEQPLAKKKETYDWYPN-HNTYFALMGTLRFLGLYRDEHQDFKDEQRRLKKLRGKGKPRKGEGKRATKKK-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D2R8-1", "uniprot_id": "RT33_MOUSE", "id": "Q9D2R8-1", "name": "Small ribosomal subunit protein mS33", "aln": "MSP-------------LSEYALRMSRLSARIFGEVARSTDSKSMKVVSLFSEQPLAKKKETYDWYPN-HNTYFALMGNLRFLGLYRDEHQDFKDEQRRLKKLRGKGKPRKGEGKRATKKK-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y291-1", "uniprot_id": "RT33_HUMAN", "id": "Q9Y291-1", "name": "Small ribosomal subunit protein mS33", "aln": "MSS-------------LSEYAFRMSRLSARLFGEVTRPTNSKSMKVVKLFSELPLAKKKETYDWYPN-HHTYAELMQTLRFLGLYRDEHQDFMDEQKRLKKLRGKEKPKKGEGKRAAKRK-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VEV5-1", "uniprot_id": "Q9VEV5_DROME", "id": "Q9VEV5-1", "name": "Small ribosomal subunit protein mS33", "aln": "MSHKYTELIKVG-----TQYARRMNYLSNRIFGEVARTTNEKSMKVVRMFSEEPIHKRDYVINWYPR-HVETHLLMKNLRDYGLFRDEHQDFKEEMKRLRKLRGKAPPKKGEGKRASKK--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53305-1", "uniprot_id": "RT27_YEAST", "id": "P53305-1", "name": "Small ribosomal subunit protein mS33", "aln": "MNVP-------------KARLLKVAELSAKIFDQNFNPSGIRTG--SKILNER--LKGPSVASYYGNPDILKFRHLKTLYPDIEFVDLEEQYRLSMVEAKKRRGKGAPKKMKKDAAATAKGKGKKKK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . :: ** ::*.: ..:. :: ::.* * . .:* . . : .* : * .::: . . :* *** *:* : . *:. ", "identical_positions": 16, "similar_positions": 36, "identity": "12.6%" }, { "cls_id": "homologset.agr.RGD:1309218", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4A6E6-1", "uniprot_id": "D4A6E6_RAT", "id": "D4A6E6-1", "name": "Heparan-sulfate 6-O-sulfotransferase", "aln": "--------------------MRRRRAGGRTMVERA-------------------------------SKFVLVVAGS---ACFMLILYQYAGPGLS-LGAPGGRAP-PDDLDLFPT----PDPHYEKKYYFPVRELERSLRFDMKGDDVIVFLHIQKTGGTTFGRHLVQNVRLEVPCDCRPGQKKCTCYRPNRRETWLFSRFSTGWSCGLHADWTELTNCVPGVLDRRDPAGLRSPRKFYYITLLRDPVSRYLSEWRHVQRGATWKTSLHMCDGRTPTPEELPPCYEGTDWSGCTLQEFMDCPYNLANNRQVRMLADLSLVGCYNLSFIPESKRAQLLLESAKKNLRGMAFFGLTEFQRKTQYLFERTFNLKFIRPFMQYNSTRAGG--VEVDEDTIRHIEELNDLDMQLYDYAKDLFQQRYQYKRQLER-REQRLRNRE--ERLLHRSKEALPREDT---EEPGRVPTEDYMSHIIEKW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QYK5-1", "uniprot_id": "H6ST1_MOUSE", "id": "Q9QYK5-1", "name": "Heparan-sulfate 6-O-sulfotransferase 1", "aln": "--------------------MRRRRAGGRTMVERA-------------------------------SKFVLVVAGS---ACFMLILYQYAGPGLS-LGAPGGRVP-PDDLDLFPT----PDPHYEKKYYFPVRELERSLRFDMKGDDVIVFLHIQKTGGTTFGRHLVQNVRLEVPCDCRPGQKKCTCYRPNRRETWLFSRFSTGWSCGLHADWTELTNCVPGVLDRRDPAGLRSPRKFYYITLLRDPVSRYLSEWRHVQRGATWKTSLHMCDGRTPTPEELPPCYEGTDWSGCTLQEFMDCPYNLANNRQVRMLADLSLVGCYNLSFIPESKRAQLLLESAKKNLRGMAFFGLTEFQRKTQYLFERTFNLKFIRPFMQYNSTRAGG--VEVDEDTIRHIEELNDLDMQLYDYAKDLFQQRYQYKRQLER-REQRLRNRE--ERLLHRSKEALPREDP---EEPGRVPTEDYMSHIIEKW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60243-1", "uniprot_id": "H6ST1_HUMAN", "id": "O60243-1", "name": "Heparan-sulfate 6-O-sulfotransferase 1", "aln": "--------------------MRRRRAGGRTMVERA-------------------------------SKFVLVVAGS---VCFMLILYQYAGPGLS-LGAPGGRAP-PDDLDLFPT----PDPHYEKKYYFPVRELERSLRFDMKGDDVIVFLHIQKTGGTTFGRHLVQNVRLEVPCDCRPGQKKCTCYRPNRRETWLFSRFSTGWSCGLHADWTELTNCVPGVLDRRDSAALRTPRKFYYITLLRDPVSRYLSEWRHVQRGATWKTSLHMCDGRTPTPEELPPCYEGTDWSGCTLQEFMDCPYNLANNRQVRMLADLSLVGCYNLSFIPEGKRAQLLLESAKKNLRGMAFFGLTEFQRKTQYLFERTFNLKFIRPFMQYNSTRAGG--VEVDEDTIRRIEELNDLDMQLYDYAKDLFQQRYQYKRQLER-REQRLRSRE--ERLLHRAKEALPREDA---DEPGRVPTEDYMSHIIEKW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q56UJ5-1", "uniprot_id": "H6S1A_DANRE", "id": "Q56UJ5-1", "name": "Heparan-sulfate 6-O-sulfotransferase 1-A", "aln": "----------------------MNLLTGRNMVERS-------------------------------SKFLFIVVGS---VLFMLILYQYVAPGMMNFGSPHGYML-EDDADLFPT----PDPHYVKKFYFPIRDLERTVDFEIKGDDVIVFLHIQKTGGTTFGRHLVQNVRLEVPCDCRPGQKKCTCYRPNRKETWLFSRFSTGWSCGLHADWTELTNCVPGVLNKKE-SRMKNQRKFYYITLLRDPVSRYLSEWRHVQRGATWKTSLHMCDGRTPTPEELPPCYEGTDWSGCTLQQFMDCPYNLANNRQVRMLADLSLVGCYNMSFIPEKKRAQVLLESAKKNLRDMAFFGLTEFQRKTQYLFERTFRLKFIRPFMQYNSTRAAG--VDLDNDTIQRIEELNDLDMQLYDYARDLFQQRYMYKRQLER-REQRLKNQPLFPFRRTSSSDSTFRDDAPESEG-SRLPTEDYMNHIINRW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0MGZ5-1", "uniprot_id": "H6S1B_DANRE", "id": "A0MGZ5-1", "name": "Heparan-sulfate 6-O-sulfotransferase 1-B", "aln": "----------------------MN-DTERNMVERT-------------------------------SKFLLIVVGS---VFFMLILYQYVAPGVINFGSPHGYLLGEEDMTIFPT----PDPHYVKKYYFPIKDLERKIDFEIKGEDVIVFLHIQKTGGTTFGRHLVQNVRLELPCDCRPGQKKCTCYRPNRKETWLFSRFSTGWSCGLHADWTELTNCVPGVLNKRE-SKSKKMRKFYYITLLRDPVSRYLSEWRHVQRGATWKTSLHMCDGRTPTPEELPPCYEGTDWSGCTLQQFMDCPYNLANNRQVRMLADLSLVGCYNLSTVPEKRRSQLLLESAKKNLRDMAFYGLTEFQRKTQYLFERTFHLKFIRPFMQYNSTRAAG--VDLDNDTIQRIEELNDLDMKLYDYAKDLFQQRYQYKHMLDR-REQRL-------LRGHASFHSPFREDGAGGEGTARLPTEDYMNHIINGW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VDR6-1", "uniprot_id": "Q9VDR6_DROME", "id": "Q9VDR6-1", "name": "Heparan-sulfate 6-O-sulfotransferase", "aln": "MPGDMHKNVSVQVDSDFALLLPSGVYEIKKMEPRSKIRTIIVFCLFLAIAGIIGFGYFCQDQVCALSKRAVILQSSDILAYNELPLHQANSINGNANGNSNGNGNSVGGITAMASKSSAPQNIIANAGLSYEDVLNDDFQFDMDGHDVMVFLHIQKTGGTSFGRHLVRDLDLKRPCECQRQRKRCYCFRPHRNENWLFSRYSTGWKCGLHADWTELTSCVDVELDKNE--GETAKRRYFYISLLRQPIARYMSEYRHVRRGATWKGSRHWCLGRQATAAELPACYKGKDWLDVDLDQFAGCESNLAANRQTRMLADLALVGCYNKSSMPAHERDRVMLASAKRNLAAMAYFGLTEYQKMSQYIFEETFNLRFAIPFEQHNTTISATAVQNLRPDQKRRIEKLNSLDIELYAFAKTLLFQRFEHLKAKDTNFEQRYANLG---NIYFKQGVTEFNWDS---NVEDGLSTDH---------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.* *: ** .:: .* . * *:* . . * . * . :.: *: : *: . *::.*.**:***********:******::: *: **:*: :*:* *:**:*.*.*****:****.***********.** *::.: *:::**:***:*::**:**:***:****** * * * ** .*. ***.**:*.** . *::* .* *** ***.******:****** * :* .* :::* ***:** **::****:*: :**:**.**.*:* ** *:*:* :. :: * ::**:**.**::** :*: *: **: : : : *** : . * : :.*:. ", "identical_positions": 169, "similar_positions": 107, "identity": "35.28%" }, { "cls_id": "homologset.agr.RGD:1309219", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XIK8-1", "uniprot_id": "CTSL2_RAT", "id": "Q5XIK8-1", "name": "CTD small phosphatase-like protein 2", "aln": "MKLRTRKASQQSSPIQTQRTARAKRKYSEVDDSLPSGGEKPSKNETGLLSSIKKFIKGSTPKEERENPSKRSRIERDIDNNLITSTP-RTGEKPDKQLSRVRRKSPVNGEAGSYEMTNQHIKQNGKLEDNPCS-GSPPRTTLLGTIFSPVFNFFSPANKNGTSGSDSPGQAVEAEEIVKQLDMEQVDEITTS-TTSAN----GAAYSNQAVQVR--PSLNNGLEEAEETVTRDIPPLTAPVAPES-GYS----SAHAEATYEEDWEVFDPYYFIKHVPPLTEEQLNRKPALPLKTRSTPEFSLVLDLDETLVHCSLNELEDAALTFPVLFQDVIYQVYVRLRPFFREFLERMSQMYEIILFTASKKVYADKLLNILDPKKQLVRHRLFREHCVCVQGNYIKDLNILGRDLSKTIIIDNSPQAFAYQLSNGIPIESWFMDKNDNELLKLIPFLEKLVELNEDVRPHIRDRFRLHDLLPPD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BG15-1", "uniprot_id": "CTSL2_MOUSE", "id": "Q8BG15-1", "name": "CTD small phosphatase-like protein 2", "aln": "MKLRTRKASQQSSPIQTQRTARAKRKYSEVDDSLPSGGEKPSKNETGLLSSIKKFIKGSTPKEERENPSKRSRIERDIDNNLITSTP-RTGEKPDKQLSRVRRKSPVNGEAGSYEMTNQHIKQNGKLEDNPCS-GSPPRTTLLGTIFSPVFNFFSPANKNGTSGSDSPGQAVEAEEIVKQLDMEQVDEITTS-TTSAN----GAAYSNQAVQVR--PSLNNGLEEAEETVTRDIPPLTAPVTPES-GYS----SAHAEATYEEDWEVFDPYYFIKHVPPLTEEQLNRKPALPLKTRSTPEFSLVLDLDETLVHCSLNELEDAALTFPVLFQDVIYQVYVRLRPFFREFLERMSQMYEIILFTASKKVYADKLLNILDPKKQLVRHRLFREHCVCVQGNYIKDLNILGRDLSKTIIIDNSPQAFAYQLSNGIPIESWFMDKNDNELLKLIPFLEKLVELNEDVRPHIRDRFRLHDLLPPD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q05D32-1", "uniprot_id": "CTSL2_HUMAN", "id": "Q05D32-1", "name": "CTD small phosphatase-like protein 2", "aln": "MRLRTRKASQQSNQIQTQRTARAKRKYSEVDDSLPSGGEKPSKNETGLLSSIKKFIKGSTPKEERENPSKRSRIERDIDNNLITSTP-RAGEKPNKQISRVRRKSQVNGEAGSYEMTNQHVKQNGKLEDNPSS-GSPPRTTLLGTIFSPVFNFFSPANKNGTSGSDSPGQAVEAEEIVKQLDMEQVDEITTSTTTSTN----GAAYSNQAVQVR--PSLNNGLEEAEETVNRDIPPLTAPVTPDS-GYS----SAHAEATYEEDWEVFDPYYFIKHVPPLTEEQLNRKPALPLKTRSTPEFSLVLDLDETLVHCSLNELEDAALTFPVLFQDVIYQVYVRLRPFFREFLERMSQMYEIILFTASKKVYADKLLNILDPKKQLVRHRLFREHCVCVQGNYIKDLNILGRDLSKTIIIDNSPQAFAYQLSNGIPIESWFMDKNDNELLKLIPFLEKLVELNEDVRPHIRDRFRLHDLLPPD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08BB5-1", "uniprot_id": "CTL2A_DANRE", "id": "Q08BB5-1", "name": "CTD small phosphatase-like protein 2-A", "aln": "MRLRVRKASQQRSATPSARTVKTKRKHSEVEHSLSTEDAKMQKRDTGIFSTIKRFIRGNAVKVEQCTPAKRSRVDCDSDSNLITSTP-TGGNLPSRANPKTRRKGPVNGDT--MTGQNKPVKPNGKLEVQAETPSSPPRTTLLGTIFSPVFSFFSPANKNATAGSDSPGQAVEAEEIVKQLDMEQLEETPTSTTTDGR----DLTFD-PALNPRPLPHIDTTVEEGEIVTEADMPPLTA-VGSNS-NYPDVPPSPPAEGTYEEDWEVFDPYFFIKHVPPLTEEQLTRKPALPLKTRSTPEFSLVLDLDETLVHCSLNELEDAALTFPVLFQDVIYQVYVRLRPFFREFLERMSQIYEIILFTASKKVYADKLLNILDPKKQLVRHRLFREHCVCVQGNYIKDLNILGRDLSKTVIIDNSPQAFAYQLSNGIPIESWFVDKNDNELLKLVPFLEKLVELNEDVRPYIRERFRLHDLLPPD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A4QNX6-1", "uniprot_id": "CTL2B_DANRE", "id": "A4QNX6-1", "name": "CTD small phosphatase-like protein 2-B", "aln": "MRLRMRKDSQQPTLARRACPARTKRKSSEVEECTG--------ESKALLSSIKKFIHGSSIKVEQDNPAKTSHLSCE----LITSTPQRKNDLQRKSIYRARRRTSINGETTNHDTN----KPNGKLEVTEEVVSSPPRTTLLGTIFSPVFNFFSPANKN---ASNSPDQVVEAEEIVKQLEMEQVEEMPTCTATSREPLSVPLYTSAMTSAFRPPPTAHTPEQESENTPHPDLPPLTAPGSPATGGYVDASITVPAEGSYEEEWEVFDPYFFIKHVPPLTEEQLTRKPALPLKTRSTPEFSLVLDLDETLVHCSLNELDDAALTFPVLFQDVIYQVYVRLRPFFREFLERMSQIYEIILFTASKKVYADKLLNILDPRKQLVRHRLFREHCVCVQGNYIKDLNILGRDLSKTIIIDNSPQAFAYQLSNGIPIESWFMDRNDSELLKLVPFLEKLVELNEDVRPHVRERFRLHDLLPPD", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:** ** *** . ..::*** ***:.. ....::*:**:**:*.: * *: .*:* *::. : ****** .: : :.**: :**:: * ***** .****************.******** .*:**.*.**********:***::* .*. :*. . . : * * .. :*.* . *:***** . : .* : **.:***:*******:*************.*********************************:**********************************:***********************:**********************************:***********************:*:**.*****:***************::*:***********", "identical_positions": 303, "similar_positions": 78, "identity": "63.26%" }, { "cls_id": "homologset.agr.RGD:1309220", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q3KR73-1", "uniprot_id": "KANL3_RAT", "id": "Q3KR73-1", "name": "KAT8 regulatory NSL complex subunit 3", "aln": "-----------------------------------------------MAHRGGERDFQTSARRMGTSLLFQLSVHERELDLVFLDHSYAKPWSAHPDASSARPTRMLFVTPRRQQENTIESDVP---------------------------------------------------IDVETVTATPAPLYDNQKARSVMNECERHVIFARTDADAPPPPEDWEEHVNRTGWTVAQNKLFNKILKALQSDRLARLANEGACNEPVLRRVAVDKCARRVRQALASVSWDTKLIQWLHTTLVETLSLPMLAAYLDALQTLKGKIPTLIDRMLVSSNTKTGAAGAEALSLLLKRPWDPAVGVLSHNKPSKLPGSPLILIASSGPSSSVFPASRRHRFWQSQLSCLGKVIPVATHLLNNGSGVG-VLQCLEHMTGAVRSKVLEIHSHFPHKPIILIGWSTGALVACHVSVMEYVTAVVCLGFPLLTVDGPRGDVDDPLLDMKTPVLFVIGQNSLQCHPEAMEDFREKIRAENSLVVVGGADDNLRISKAKKKSEGLTQSMVDRCIQDEIVDFLTGVLTRAEGH-VGS-EPRDQ--------------DAEKKKKPRDVARRDLAFEIPERGSRPASP--------------------AARLPTSPSGSEDLSSVSSSPTSSPKTKGTTVTSAQKSSQ--IGTSQLLRRHVQRTDAVLTHRQAQ---------------------------VPISSEPVEEVEKEELRVQLKRHHPSSPLPGAKPSK-----------RPKIKVSLISQGDTVGGPCTLSQGGTPEAAGGKPITMTLG--ASAGAKELTGLLTTAKSSSSEGGVTASAAPSVASS--------------------------------NATPNAIH-TLQSRLVATSPGSSLPGAASASSLLQG---LSFSLQDISSKTTG----------LPGSPSPGPAPQATSVKLPTPMQSLGAITTGTSTIVRTIPVATTLSSLAATPGGKPTAIHQLLTNG-----------------GLAKLASSLPGLAQISN-------------QASGLKVPTTITLTLRGQPSRITTLSPMGSGAAASEEPNSQMLPSSSQRLPPAP-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2RSY1-1", "uniprot_id": "KANL3_MOUSE", "id": "A2RSY1-1", "name": "KAT8 regulatory NSL complex subunit 3", "aln": "-----------------------------------------------MAHRGGERDFQTSARRMGTSLLFQLSVHERELDLVFLDHSYAKPWSAHPDASSARPTRMLFVTPRRQQENTIESDVP---------------------------------------------------IDVETVTATPVPLYDNQKARSVMNECERHVIFARTDADAPPPPEDWEEHVNRTGWTVAQNKLFNKILKALQSDRLARLANEGACNEPVLRRVAVDKCARRVRQALASVSWDTKLTQWLHTTLVETLSLPMLAAYLDALQTLKGKIPTLIDRMLVSSNTKTGAAGAEALSLLLKRPWDPAVGVLSHNKPSKLPGSPLILIVSSGPSSSVFPASRRHRFWQSQLSCLGKVIPVATHLLNNGSGVG-VLQCLEHMIGAVRSKVLEIHSHFPHKPIILIGWNTGALVACHVSVMEYVTAVVCLGFPLLTVDGPRGDVDDPLLDMKTPVLFVIGQNSLQCHPEAMEDFREKIRAENSLVVVGGADDNLRISKAKKKSEGLTQSMVDRCIQDEIVDFLTGVLTRAEGH-VGS-EPRDQ--------------DAEKKKKPRDLTRRDLAFEIPERGSRPASP--------------------AARLPTSPSGSEDLSSVSSSPTSSPKTKVTTVTSTQKSSQ--IGTSQLLKRHVQRTEAVLTHRQAQAQFAAFLKQNMLVRKAFPPGTSS-CLFVPISSESVEDIEKEELRVQLKRHHSSSPLPGAKPSK-----------RPKIKVSLISQGDTVGGPCTLSQGGTPEAAGGKPITMTLG--ASAGAKELTGLLTTAKSSSSEGGGTASTTPSVASS--------------------------------SATPNAIH-TLQSRLVATSPGSSLPGTASASSLLQG---LSFSLQDISSKTSG----------LPGSPSPGPAPQATSVKLPTPMQSLGAITTGTSTIVRTIPVATTLSSLGATPGGKPTAIHQLLTNG-----------------SLAKLASSLPGLAQISN-------------QASGLKVPTTITLTLRGQPSRITTLSPMGSGATPSEEPNSQMLPSSSQRLPPAP-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P2N6-1", "uniprot_id": "KANL3_HUMAN", "id": "Q9P2N6-1", "name": "KAT8 regulatory NSL complex subunit 3", "aln": "-----------------------------------------------MAHRGGERDFQTSARRMGTSLLFQLSVHERELDLVFLDHSYAKPWSAHPDASSARPTRMLFVTPRRQHESTIESDVP---------------------------------------------------IDVETVTSTPMPLYDNQKARSVMNECERHVIFARTDADAPPPPEDWEEHVNRTGWTMAQNKLFNKILKALQSDRLARLANEGACNEPVLRRVAVDKCARRVRQALASVSWDTKLIQWLHTTLVETLSLPMLAAYLDALQTLKGKIPTLIDRMLVSSNTKTGAAGAEALSLLLKRPWDPAVGVLSHNKPSKLPGSPLILIASSGPSSSVFPTSRRHRFWQSQLSCLGKVIPVATHLLNNGSGVG-VLQCLEHMIGAVRSKVLEIHSHFPHKPIILIGWNTGALVACHVSVMEYVTAVVCLGFPLLTVDGPRGDVDDPLLDMKTPVLFVIGQNSLQCHPEAMEDFREKIRAENSLVVVGGADDNLRISKAKKKSEGLTQSMVDRCIQDEIVDFLTGVLTRAEGH-MGS-EPRDQ--------------DAEKKKKPRDVARRDLAFEVPERGSRPASP--------------------AAKLPASPSGSEDLSSVSSSPTSSPKTKVTTVTSAQKSSQ--IGSSQLLKRHVQRTEAVLTHKQAQAQFAAFLKQNMLVRKALPPGTSS-CLFVPISSEPPEEGEKEDLRVQLKRHHPSSPLPGSKTSK-----------RPKIKVSLISQGDTAGGPCAPSQGSAPEAAGGKPITMTLGQ-ASAGAKELTGLLTTAKSSSSEGGVSASPVPSVVSS--------------------------------STAPSALH-TLQSRLVATSPGSSLPGATSASSLLQG---LSFSLQDISSKTSG----------LPANPSPGPAPQATSVKLPTPMQSLGAITTGTSTIVRTIPVATTLSSLGATPGGKPTAIHQLLTNG-----------------GLAKLASSLPGLAQISN-------------QASGLKVPTTITLTLRGQPSRITTLSPMGSGAAPSEESSSQVLPSSSQRLPPAP-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q499B3-1", "uniprot_id": "KANL3_DANRE", "id": "Q499B3-1", "name": "KAT8 regulatory NSL complex subunit 3", "aln": "-----------------------------------------------MFRPGGERDFQTSARRMGTSLLFQLSVHERELDLVFLDHSYAKPWNAHPDASSARPTRMLFVTPRRQPEASGDSDMS---------------------------------------------------IDVETVTPTPMPLYDNQKARSVMNECDRHVLFARTVADGPPPPDDWEEHINKTGWSLAQNKLFNKVLKALQAERLGRLANDGACNEPVLRRIAVDKCARKVRHALSSVSWDIKLTHWLHNTLLESLSLAMLAAYLDVLQTLKSKVPSLIDRMLLSSSVKTGAAGAEALSLLLKRPWDPAVGVLSHNKPSKLPGSPLILIAPSGPTNPAFPTSRRMRFWQSQLSCLGKVIPINVHVG-SGANVG-ITQCLEHMIGTVRGKVIEVHSHFPHKPIILVGWNVGSLMACHVSLMEYMTAVVCLGFPLQTISGPRGDVDDPLLDMKTPVLFVVGQNALQCSPENMEEFREKIRADNSLVVVGGADDSLRINSTKMKTEGLTQTMVDRCIQDEIVDFLTGVLTRSESHGHGSGETRDL--------------DAEKKK-----PRRELPFDLDR--SRPSSP--------------------AVR---------DMSSVCSSPTASPKPKTVGLSPAQKSSL--ITATQLLKTHMQRSGTVLTHKQAQAQFAAFMKHNMLVRKSIPPGSPS-CLFVPVPSEQVEGLERDDMRVHLKRRQTPSPTP-TKASK-----------RAKIKVTIVSHGDAAGN--TPGSTAQEVGLSGKPLGLTVGQTTVSGAKELSELLSAQRS-----GGLAEVSGALASS--------------------------------EGSFHSLQGSVISRSSSPVQAAGTAQAPSASSLLQG---LSLSLQEINTKSPG----------VPS------TTQVSGGKPQGQGQVLSSLSPGSGTLVRAVPMVSTGSGMTKT-----TAIHQLLTNG-----------------GLAKLANSLPGLAHVSS-------------QSS-------------------------GTSST----------PRSKQRRPR---------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KF25-1", "uniprot_id": "A0A0B4KF25_DROME", "id": "A0A0B4KF25-1", "name": "", "aln": "MKESGSVSKNQPQTSEARGSIITYSPSKFLTSVGTGRTTYSTHTHTTTATSAATTATKTNNLPMGGSSAAYYVVKAGSLGSAASMSGCIKVSSPPKGPPMAKSPALVVTSPCTPTESSSTISAPSESSFSEKMEHSYMRDTPVRSDVHNGLTPARNILVRHPPQCPSCHTYPPQHEELSEIQQAHVPPYDEVVAKEAMNECARIAKYVKNNNSDE---QDWVARVNKFNWTPMQEMVFEKVCSILDQDQLARLANDKRQHEPIHRRISSDKSASRFRKLLASVAWESRITQWIHALLMEHLSPSYMASYLEILQTLKTKLPTLVDKMLFGRPLNN---SQELLAPVMKKRWEPNIMPKSR----QLTHNAIMVVLPNMPTTG--TVSDRMQKWYQALSTITQVVQISLPNTNNRIGNQNLDHVAETIVSITRVKINELRTENPSRGIILVGFNAGAALALQVALSESVACVVCMGFAYNTIRGPRGTPDDRMLDIKAPILFVIGQNSARTSQEEMEGLRERMQSESSLVVVGSADDALRVPKSKRRIEGVTQSMVDYMVVEEIFEFVNRTLSNPPGPRMPTCLMHQQGYQRLPKQSPHILADGNANKAVQQMRKRKMDGGLDDSMGQPSKTKFVPHNRVHKPKPPRLIDPFAVKRKVGRPRTRPLPNVGGSARSVSQKGAPHPDQPKLSGEEPNQSIEFILDDAQDYGDAQTTAGGSASLPKVITPGVLGKQLPPVNLAAGTKIKMIPSSQFVQIKSLPSQSKLINYTLNKPSVGTSSTANIGSVVKTLPCSSVSGQQIITLKTPSGQTQQFATAATSTGAAGSSTSTGTGQKKYTVFKNANGMTMLHLTKSVPTTGSSSGSANMDLSNIIDMPIVFADNEGNIPEHQQADKDIKPAPIRSANKSPLIISQKIIKEANKPSGMVTSGSITAVSKPGNIVLNKGLQQLLNSSPGGTLATQNKVVYLNRSTIKPMGNVAPGTHRVPIRIVSTPNTGGAVTTTASSSPIMVDPATGSKVAKTVNVQTIKPTGSVLAQGTIRQAGNVGTKSYLQMINTAPGASKTVAGDGKGSVRNIYFKSATGLKQLPVQMLGNRIPGGAVISSTASASSGSPGLRRVVNIGPVSKVTATSTTSSSIAATLTHNKM", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. :*. ** * *: .*. . . * .. ... *:.. ::..:* * : . . ::. : : * **: *:..**** * . :.:. . :** ::*: .*: *: :*:*: . *: ::*.****: :**: **:: **.* :.*: *:**:*: :: :*:* *:* ** . :*:**: ***** *:*:*:*:**.. :. . * *: ::*: *:* : *: :*. ..:::: .. *:. ..* * : * . ** : :*: : . . : : * : . .* *: *:::. * : ***:*:..*: :* :*:: * ::.***:**. *: **** ** :**:*:*:***:***: : * ** :**:::::.******.*** **: .:* : **:**:*** : :**.:*:. .*:.. . : :: *.: :* :*.: : .:*:.. *.: :..* .*. : .: .: *. : ::: . * . * .. :.*. : : :* . .* :..: . ::: . * . . . .*.. * : *: . : : :. : * . .: : : .. . . :: * *. .**:: ..:.* :.: . : :.: ..* .. . : . . : . :: : ..* . :: .: ** :: .:: .:..: * *. . ", "identical_positions": 170, "similar_positions": 298, "identity": "14.87%" }, { "cls_id": "homologset.agr.RGD:1309221", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZX76-1", "uniprot_id": "A0A8I5ZX76_RAT", "id": "A0A8I5ZX76-1", "name": "Eukaryotic translation initiation factor 3 subunit K", "aln": "-MAMFEQMR----ANVGKLLKGIDRYNPENLATLERYVETQAKENAYDLEANLAVLKLYQFNPAFFQTTVTAQILLKALTNLPHTDFTLCKCMIDQAHQEERPIRQILYLGDLLETCHFQAFWQALDENMDLLEGITGFEDSVRKFICHVVGITYQHIDRWLLAEMLGDLTDNQLRVWMSKYGWSADESGQVFICSQEESIKPKNIVEKIDFDSVSSIMASSQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DBZ5-1", "uniprot_id": "EIF3K_MOUSE", "id": "Q9DBZ5-1", "name": "Eukaryotic translation initiation factor 3 subunit K", "aln": "-MAMFEQMR----ANVGKLLKGIDRYNPENLATLERYVETQAKENAYDLEANLAVLKLYQFNPAFFQTTVTAQILLKALTNLPHTDFTLCKCMIDQAHQEERPIRQILYLGDLLETCHFQAFWQALDENMDLLEGITGFEDSVRKFICHVVGITYQHIDRWLLAEMLGDLTDNQLKVWMSKYGWSADESGQVFICSQEESIKPKNIVEKIDFDSVSSIMASSQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UBQ5-1", "uniprot_id": "EIF3K_HUMAN", "id": "Q9UBQ5-1", "name": "Eukaryotic translation initiation factor 3 subunit K", "aln": "-MAMFEQMR----ANVGKLLKGIDRYNPENLATLERYVETQAKENAYDLEANLAVLKLYQFNPAFFQTTVTAQILLKALTNLPHTDFTLCKCMIDQAHQEERPIRQILYLGDLLETCHFQAFWQALDENMDLLEGITGFEDSVRKFICHVVGITYQHIDRWLLAEMLGDLSDSQLKVWMSKYGWSADESGQIFICSQEESIKPKNIVEKIDFDSVSSIMASSQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q567V6-1", "uniprot_id": "EIF3K_DANRE", "id": "Q567V6-1", "name": "Eukaryotic translation initiation factor 3 subunit K", "aln": "MATTFEQMR----ANVGKLLRGIDRYNPENLATLERYVDTQARENAYDLEANLAVLKLYQFNLAYFQTTVTAQILLKALTNLPHTDFTLCKCMIDQTHQEERPIRQILYLGNLLETCHFQSFWASLEENRDLIDGITGFEESVRKFICHVVGITYQNIEYRLLAEMLGDPLDTQVKVWMNKYGWTENEDGQIFIHNQEESVKPKNIVEKIDFESVSSIMATSQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W2D9-1", "uniprot_id": "EIF3K_DROME", "id": "Q9W2D9-1", "name": "Eukaryotic translation initiation factor 3 subunit K", "aln": "-MSHLVKMENGQSQTIQEMLGCIERYNPDHLKTLESYVQDQAKNNTYDLEANLAVLKLYQFNPHMLNFDITYTILLKSLTSLPHTDFVMAKCLLLPQQMKDENVQTIIDLADILERADFTLFWQRAEVNRNMFRHITGFHDSIRKFVSHVVGTTFQTIRKDLLKELLGGIEDSTLESWIKRNGWKNQGQGLVIVAMQDDKIKTKNITEKIEFDNVGALMAQCL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :*. .: ::* *:****::* *** **: **::*:**************** :: :* ****:**.******.:.**:: : ::. :: *: *.::** ..* ** : * ::: ****.:*:***:.**** *:* * ** *:**. *. :. *:.: **. : .* ::: *::.:*.***.***:*:.*.::** . ", "identical_positions": 92, "similar_positions": 74, "identity": "41.26%" }, { "cls_id": "homologset.agr.RGD:1309222", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P22646-1", "uniprot_id": "CD3E_MOUSE", "id": "P22646-1", "name": "T-cell surface glycoprotein CD3 epsilon chain", "aln": "MRWNTFWGILCLSLLA--------------------------------------------------------------------------VGTCQDDAEN--------IEYKVSISGTSVELTCPLDSDENLKWEKNGQELP-QKHDK-------HLVLQDFSEVEDSGYYVCYTPASN---KNTYLYLKARVCEYCVEVDLTAVAIIIIVDICITLGLLMVIYYWSKNRKAKAKPVTRGTGAGSRPRGQNKERPPPVPNPDYEPIRKGQRDLYSGLNQRAV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AAG4-1", "uniprot_id": "A0A8I6AAG4_RAT", "id": "A0A8I6AAG4-1", "name": "T-cell surface glycoprotein CD3 epsilon chain", "aln": "MQWNAFWSILGLSLLAGCFLVQLPPELAGSLCLIPCSKCPSPWHRKYCYVTVGGKDLRCQFWSDRSTTLLVWNFRHSQHLLTHVSPACFPVGTCQEDIEDTVTDDGAQKQYEVSISGTSVELTCPLENEDNLKWEKNDKVLP-DKNEK-------HLVLEDFSEVKDSGYYVCYTESSR---KNTYLYLKARVCENCMEVDLTAVSIIIIVDICITLGLLMVVYYWSKKRKAKAKPVTRGTGTGGRPRGQNKERPPPVPNPDYEPIRKGQRDLYSGLNQRAV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P07766-1", "uniprot_id": "CD3E_HUMAN", "id": "P07766-1", "name": "T-cell surface glycoprotein CD3 epsilon chain", "aln": "MQSGTHWRVLGLCLLS--------------------------------------------------------------------------VGVWGQDGNEEMGG-ITQTPYKVSISGTTVILTCPQYPGSEILWQHNDKNIGGDEDDKNIGSDEDHLSLKEFSELEQSGYYVCYPRGSKPEDANFYLYLRARVCENCMEMDVMSVATIVIVDICITGGLLLLVYYWSKNRKAKAKPVTRGAGAGGRQRGQNKERPPPVPNPDYEPIRKGQRDLYSGLNQRRI", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: .:.* :* *.**: **. :* :: *:******:* **** .:: *::*.: : ::.:* ** *::***:::*******. .*. * ****:***** *:*:*: :*: *:******* ***:::*****:***********:*:*.* ********************************* :", "identical_positions": 115, "similar_positions": 48, "identity": "40.78%" }, { "cls_id": "homologset.agr.RGD:1309224", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZV40-1", "uniprot_id": "D3ZV40_RAT", "id": "D3ZV40-1", "name": "", "aln": "MAQGIADPQHPGHRPQRSLGIVVLHFSSDAVPTVKFHPKGGPQLPATFAAVRGVFTFSWRGAGAVGLRRGPRRLNNKRGAAKRQEDRTMSKGPGPGGSAASSAPPAATAQVLQAQPEKPQHYTYLKEFRTEQCPLFVQHKCTQHRPYTCFHWHFVNQRRRRSIRRRDGTFNYSPDVYCTKYDEATGLCPEGDECPFLHRTTGDTERRYHLRYYKTGICIHETDSKGNCTKNGLHCAFAHGPHDLRSPVYDIRELQAMEALQNGQTTVEGSIEGQSAGAASHAMIEKILSEEPRWQETAYVLGNYKTEPCKKPPRLCRQGYACPYYHNSKDRRRSPRKHKYRSSPCPNVKHGDEWGDPGKCENGDTCQYCHTRTEQQFHPEIYKSTKCNDMQQSGSCPRGPFCAFAHIEPPPLSDDVPPSSAVSSPTQPGPVLYMPSAAGDSVPVSPSSPHAPDLSALLCRSSGLASPPHLCSSPPGPSRKISNLEGLVFPGEASLAPGSYKKAPGCEREDQVGAEYLKNFKCQAKLKPHSLEPRSQEQPLLQPKQDVLGILPVGSPLTSSISSSITSSLAATPPSPAGTSSAPGMNANALPFYPTSDTVESVIESALDDLDLNEFGVAALEKTFDNSTVPHPSNITIGGSLLQSSAPVNIPGSLGSSASFHSASPSPPVSLSSHFLQQPQGHLSQSENTFLGTSASHGSLGLNGMNSSIWEHFASGSFSPGTSPAFLSGPGAAELARLRQELDEANGTIKQWEESWKQAKQACDAWKKEAEEAGERASAAGAECELAREQRDALELRVKKLQEELERLHTVPEAQTLPAAPDLEALSLSTLYSIQKQLRVHLEQVDKAVFHMQSVKCLKCQEQTR--TVLPCQHAVLCELCAE-GSECPVCQPGRAHALQS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BL48-1", "uniprot_id": "UNK_MOUSE", "id": "Q8BL48-1", "name": "RING finger protein unkempt homolog", "aln": "----------------------------------------------------------------------------------------MSKGPGPGGSAASSAPPAATAQVLQAQPEKPQHYTYLKEFRTEQCPLFVQHKCTQHRPYTCFHWHFVNQRRRRSIRRRDGTFNYSPDVYCTKYDEATGLCPEGDECPFLHRTTGDTERRYHLRYYKTGICIHETDSKGNCTKNGLHCAFAHGPHDLRSPVYDIRELQAMEALQNGQTTVEGSIEGQSAGAASHAMIEKILSEEPRWQETAYVLGNYKTEPCKKPPRLCRQGYACPYYHNSKDRRRSPRKHKYRSSPCPNVKHGDEWGDPGKCENGDACQYCHTRTEQQFHPEIYKSTKCNDMQQAGSCPRGPFCAFAHIEPPPLSDDVQPSSAVSSPTQPGPVLYMPSAAGDSVPVSPSSPHAPDLSALLCRNSGLGSPSHLCSSPPGPSRKASNLEGLVFPGESSLAPGSYKKAPGFEREDQVGAEYLKNFKCQAKLKPHSLEPRSQEQPLLQPKQDVLGILPVGSPLTSSISSSITSSLAATPPSPAGTNSTPGMNANALPFYPTSDTVESVIESALDDLDLNEFGVAALEKTFDNSAVPHPSSVTIGGSLLQSSAPVNIPGSLGSSASFHSASPSPPVSLSSHFLQQPQGHLSQSENTFLGTSASHGSLGLNGMNSSIWEHFASGSFSPGTSPAFLSGPGAAELARLRQELDEANGTIKQWEESWKQAKQACDAWKKEAEEAGERASAAGAECELAREQRDALELRVKKLQEELERLHTVPEAQTLPAAPDLEALSLSTLYSIQKQLRVHLEQVDKAVFHMQSVKCLKCQEQTR--AVLPCQHAVLCELCAE-GSECPVCQPSRAHALQS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9C0B0-1", "uniprot_id": "UNK_HUMAN", "id": "Q9C0B0-1", "name": "RING finger protein unkempt homolog", "aln": "----------------------------------------------------------------------------------------MSKGPGPGGSAASSAPPAATAQVLQAQPEKPQHYTYLKEFRTEQCPLFVQHKCTQHRPYTCFHWHFVNQRRRRSIRRRDGTFNYSPDVYCTKYDEATGLCPEGDECPFLHRTTGDTERRYHLRYYKTGICIHETDSKGNCTKNGLHCAFAHGPHDLRSPVYDIRELQAMEALQNGQTTVEGSIEGQSAGAASHAMIEKILSEEPRWQETAYVLGNYKTEPCKKPPRLCRQGYACPYYHNSKDRRRSPRKHKYRSSPCPNVKHGDEWGDPGKCENGDACQYCHTRTEQQFHPEIYKSTKCNDMQQSGSCPRGPFCAFAHVEQPPLSDDLQPSSAVSSPTQPGPVLYMPSAAGDSVPVSPSSPHAPDLSALLCRNSSLGSPSNLCGSPPGSIRKPPNLEGIVFPGESGLAPGSYKKAPGFEREDQVGAEYLKNFKCQAKLKPHSLEPRSQEQPLLQPKQDMLGILPAGSPLTSSISSSITSSLAATPPSPVGTSSVPGMNANALPFYPTSDTVESVIESALDDLDLNEFGVAALEKTFDNSTVPHPGSITIGGSLLQSSAPVNIPGSLGSSASFHSASPSPPVSLSSHFLQQPQGHLSQSENTFLGTSASHGSLGLNGMNSSIWEHFASGSFSPGTSPAFLSGPGAAELARLRQELDEANSTIKQWEESWKQAKQACDAWKKEAEEAGERASAAGAECELAREQRDALEVQVKKLQEELERLHAGPEPQALPAFSDLEALSLSTLYSLQKQLRAHLEQVDKAVFHMQSVKCLKCQEQKR--AVLPCQHAALCELCAE-GSECPICQPGRAHTLQS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q86B79-1", "uniprot_id": "UNK_DROME", "id": "Q86B79-1", "name": "RING finger protein unkempt", "aln": "-----------------------------------------------------------------------------------------------------MLANETNKLLLSSQQEKPNHYTYLKEFRVEQCQSFLQHKCNQHRPFVCFNWHFQNQRRRRPVRKRDGTFNYSADNYCTKYDETTGICPEGDECPYLHRTAGDTERRYHLRYYKTCMCVHDTDSRGYCVKNGLHCAFAHGMQDQRPPVYDIKEL---ETLQNAESTLDSTNALNALDKE-----RNLMNEDPKWQDTNYVLANYKTEPCKRPPRLCRQGYACPQYHNSKDKRRSPRKYKYRSTPCPNVKHGEEWGEPGNCEAGDNCQYCHTRTEQQFHPEIYKSTKCNDVQQAGYCPRSVFCAFAHVEPCSMDD---------------------------------------------------------------------------PRENSLS---------------------------ASLANTSLLTRSS-APINIPN----------TTLSNSINDFNSGSFAVNIPS------------SSLTYSPTN--------------HANLFNVDAFNYGGSN-------KLSNSLSATQNDSSLFFPSRIISPGFGDGLSISPSVRIS---------ELNTIRDDINSSSVGN-SLFENTLNT------AKNAFSLQS----LQSQNNSDLGRITNELLTKNAQIHKLNG---------------------RFEDMACKLKIAELHRDKAKQEAQEWKERYD-----LAQIQLNLPAELRDLSIQKLKQLQSKLRTDLEEVDKVLYLENAKKCMKCEENNRTVTLEPCNHLSICNTCAESVTECPYCQVPVITTHT-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :. :*.:* ***:*********.*** *:****.****:.**:*** ******.:*:********.* *******:**:********:****:************** :*:*:***:* *.*********** :* *.*****:** *:***.::*::.: :: . .:::.*:*:**:* ***.********:************ ******:******:****:********:***:**:** ** ************************:**:* ***. ******:* .:.* * * .*: *.* ** .**. *: *: :.*:.**.. :.*:*.. ** .:*.: **. . * *.* *:: .* .:: . * *..:.: :*. : *.. .. * **.* :* .*. .: : .:*..: ** * :*: *..:** : *.. . ::*.*: :** *. *:: : * . ..: ::*. :** : ..:: :*. : * .:*. **:..* .:*.:**..**:***.:: :: **:**:*:.* :: **:* :*: *** :*** ** : ", "identical_positions": 300, "similar_positions": 182, "identity": "33.3%" }, { "cls_id": "homologset.agr.RGD:1309225", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q14240-1", "uniprot_id": "IF4A2_HUMAN", "id": "Q14240-1", "name": "Eukaryotic initiation factor 4A-II", "aln": "MSGGSADYNREHGGPEGMDPDGVIESNWNEIVDNFDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFAISILQQLEIEFKETQALVLAPTRELAQQIQKVILALGDYMGATCHACIGGTNVRNEMQKLQAEAPHIVVGTPGRVFDMLNRRYLSPKWIKMFVLDEADEMLSRGFKDQIYEIFQKLNTSIQVVLLSATMPTDVLEVTKKFMRDPIRILVKKEELTLEGIKQFYINVEREEWKLDTLCDLYETLTITQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINFVTEEDKRILRDIETFYNTTVEEMPMNVADLI-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5RKI1-1", "uniprot_id": "IF4A2_RAT", "id": "Q5RKI1-1", "name": "Eukaryotic initiation factor 4A-II", "aln": "MSGGSADYNREHGGPEGMDPDGVIESNWNEIVDNFDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFAISILQQLEIEFKETQALVLAPTRELAQQIQKVILALGDYMGATCHACIGGTNVRNEMQKLQAEAPHIVVGTPGRVFDMLNRRYLSPKWIKMFVLDEADEMLSRGFKDQIYEIFQKLNTSIQVVLLSATMPTDVLEVTKKFMRDPIRILVKKEELTLEGIKQFYINVEREEWKLDTLCDLYETLTITQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINFVTEEDKRILRDIETFYNTTVEEMPMNVADLI-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P10630-1", "uniprot_id": "IF4A2_MOUSE", "id": "P10630-1", "name": "Eukaryotic initiation factor 4A-II", "aln": "MSGGSADYNREHGGPEGMDPDGVIESNWNEIVDNFDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFAISILQQLEIEFKETQALVLAPTRELAQQIQKVILALGDYMGATCHACIGGTNVRNEMQKLQAEAPHIVVGTPGRVFDMLNRRYLSPKWIKMFVLDEADEMLSRGFKDQIYEIFQKLNTSIQVVLLSATMPTDVLEVTKKFMRDPIRILVKKEELTLEGIKQFYINVEREEWKLDTLCDLYETLTITQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINFVTEEDKRILRDIETFYNTTVEEMPMNVADLI-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q02748-1", "uniprot_id": "IF4A_DROME", "id": "Q02748-1", "name": "Eukaryotic initiation factor 4A", "aln": "MDDR---NEIPQDGPASMEPEGVIESTWHEVYDNFDDMNLREELLRGIYGYGFEKPSAIQQRAIIPCVRGRDVIAQAQSGTGKTATFSIAILQQIDTSIRECQALILAPTRELATQIQRVVMALGEYMKVHSHACIGGTNVREDARILESGC-HVVVGTPGRVYDMINRKVLRTQYIKLFVLDEADEMLSRGFKDQIQDVFKMLPPDVQVILLSATMPPDVLEVSRCFMRDPVSILVKKEELTLEGIKQFYVNVKQENWKLGTLCDLYDTLSITQSVIFCNTRRKVDQLTQEMSIHNFTVSAMHGDMEQRDREVIMKQFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPSNRENYIHRIGRGGRFGRKGVAINFITDDDRRILKDIEQFYHTTIEEMPANIADLI-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P10081-1", "uniprot_id": "IF4A_YEAST", "id": "P10081-1", "name": "ATP-dependent RNA helicase eIF4A", "aln": "----------MSEGITDIE-ESQIQTNYDKVVYKFDDMELDENLLRGVFGYGFEEPSAIQQRAIMPIIEGHDVLAQAQSGTGKTGTFSIAALQRIDTSVKAPQALMLAPTRELALQIQKVVMALAFHMDIKVHACIGGTSFVEDAEGLRDAQ--IVVGTPGRVFDNIQRRRFRTDKIKMFILDEADEMLSSGFKEQIYQIFTLLPPTTQVVLLSATMPNDVLEVTTKFMRNPVRILVKKDELTLEGIKQFYVNVEEEEYKYECLTDLYDSISVTQAVIFCNTRRKVEELTTKLRNDKFTVSAIYSDLPQQERDTIMKEFRSGSSRILISTDLLARGIDVQQVSLVINYDLPANKENYIHRIGRGGRFGRKGVAINFVTNEDVGAMRELEKFYSTQIEELPSDIATLLN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .:: :. *::.:.:: :****:* *.****::.****:*********:* :.* **:**********.**:*: **::: ..: ***:******** ***:*::**. :* *******.. :: . *. :********:* ::*: : .. **:*:********* ***:** ::* * . **:******* *****: ***:*: *****:***********:**:.*::* * ***:::::**:*** ******: ** :: .*****::.*: *::*:.**::*******:**:**********************:*:**********************:*::* ::::* ** * :**:* ::* *: ", "identical_positions": 229, "similar_positions": 104, "identity": "56.13%" }, { "cls_id": "homologset.agr.RGD:1309226", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q95029-1", "uniprot_id": "CATL1_DROME", "id": "Q95029-1", "name": "Cathepsin L1", "aln": "MNHLGVFETRFRPRTRHKSQRAQLIPEQITMRTAVLLPLLALLAVAQAVSFADVVMEEWHTFKLEHRKNYQDETEERFRLKIFNENKHKIAKHNQRFAEGKVSFKLAVNKYADLLHHEFRQLMNGFNYTLHKQLRAADESFKGVTFISPAHVTLPKSVDWRTKGAVTAVKDQGHCGSCWAFSSTGALEGQHFRKSGVLVSLSEQNLVDCSTKYGNNGCNGGLMDNAFRYIKDNGGIDTEKSYPYEAIDDS-CHFNKGTVGATDRGFTDIPQGDEKKMAEAVATVGPVSVAIDASHESFQFYSEGVYNEPQCDAQNLDHGVLVVGFG---TDESGEDYWLVKNSWGTTWGDKGFIKMLRNKENQCGIASASSYPLV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M1NEU9-1", "uniprot_id": "A0A8M1NEU9_DANRE", "id": "A0A8M1NEU9-1", "name": "", "aln": "-------------------------------MMFALLVTLCISAVFAASSIDIQLDDHWNSWKSQHGKSYHEDVEVG-RRMIWEENLKKIEQHNFEYSYGNHTFKMGMNQFGDMTNEEFRQAMNGYKHDPNRTS-------QGPLFMEPSFFAAPQQVDWRQRGYVTPVKDQKQCGSCWSFSSTGALEGQLFRKTGKLISMSEQNLVDCSRPQGNQGCNGGLMDQAFQYVKENKGLDSEQSYPYLARDDLPCRYDPRFNVAKITGFVDIPRGNELALMNAVAAVGPVSVAIDASHQSLQFYQSGIYYERACSSSRLDHAVLVVGYGYQGADVAGNRYWIVKNSWSDKWGDKGYIYMAKDKNNHCGVATTASYPLM", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P07711-1", "uniprot_id": "CATL1_HUMAN", "id": "P07711-1", "name": "Procathepsin L", "aln": "------------------------------MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMN-EEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPR---------KGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEES-CKYNPKYSVANDTGFVDIPK-QEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q91ZF2-1", "uniprot_id": "CAT7_MOUSE", "id": "Q91ZF2-1", "name": "Cathepsin 7", "aln": "------------------------------MTPTVFLSILCLGVALAAPAPDYNLDAEWEEWKRSNDRTYSPE-EEKQRRAVWEGNVKWIKQHIMENGLWMNNFTIEMNEFGDMTGEEMKMLTESSSYPLRN-----------GKHIQKRNPKIPPTLDWRKEGYVTPVRRQGSCGACWAFSVTACIEGQLFKKTGKLIPLSVQNLMDCSVSYGTKGCDGGRPYDAFQYVKNNGGLEAEATYPYEAKAKH-CRYRPERSVVKVNRFFVVPR-NEEALLQALVTHGPIAVAIDGSHASFHSYRGGIYHEPKCRKDTLDHGLLLVGYGYEGHESENRKYWLLKNSHGERWGENGYMKLPRGQNNYCGIASYAMYPAL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZZ07-1", "uniprot_id": "CAT7_RAT", "id": "D3ZZ07-1", "name": "Cathepsin 7", "aln": "------------------------------MTVAVFLAILCLRAALAAPRPDYSLDAEWEEWKRNNAKTYSPE-EEKQRRAVWEENVKMIKWHTMQNGLWMNNFTIEMNEFGDMTGEEMRMMTDSSALTLRN-----------GKHIQKRNVKIPKTLDWRDTGCVAPVRSQGGCGACWAFSVAASIESQLFKKTGKLIPLSVQNLIDCTVTYGNNDCSGGKPYTAFQYVKNNGGLEAEATYPYEAKLRH-CRYRPERSVVKIARFFVVPR-NEEALMQALVTYGPIAVAIDGSHASFKRYRGGIYHEPKCRRDTLDHGLLLVGYGYEGHESENRKYWLLKNSHGEQWGERGYMKLPRDQNNYCGIASYAMYPLL", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* :.: . : : .* :* : : * : * * ::: * : * * . .*.: :* :.*: .*:: :. . . . * :*** * *:.*: * **:**:** :..:*.* *:*:* *:.:* ***:**: *.:.*.** **:*:::* *:::* :*** * *:: .. * :*: :* : :*:.: **::****..* *: * *:* * * . :**.:*:**:* : .. **::*** . ** *:: : :.:.* **:*: : ** :", "identical_positions": 91, "similar_positions": 103, "identity": "24.27%" }, { "cls_id": "homologset.agr.RGD:1309227", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4ADG4-1", "uniprot_id": "D4ADG4_RAT", "id": "D4ADG4-1", "name": "", "aln": "---MIRCLSDEVQAKLRSGLALSSLGQCVEELTLNSIDAEATCVAIRVNMETFQVQVIDNGLGMAGDDVEKVGNRYFTSKCHSVRDLENPTFYGFRGEALASIADMASAVEISSKKSTTLKTFVKMFQNGKALAA----------READLTRPSVGTTVTVYNLFYQFPVRR---KSMDPRLEFEKVRQRVEALSLMHPSISFSLRNDV-----------SGSMILQLPKTKDICSRFCQIYG-LGKSQKLREIHYKYKEFEFNGYISSEAHYNKNMQFLFVNRRLVLRTKLHKLIDFLLRKESIICRPKNGSASRQMNSSPRHRSASELHGIYVINVQCPFCEYDVCIEPAKTLIEFQNWDTVLICVQEGIKKFLKQEKLFVELSSEDIKEFNEDNGFSLIGTTLQTQS-THEKCDQSSFQEACNNILDSYEMFNLQSKAVKRIATLENRTTQNSGDSGAIRKKTEDS--YTYESDDLGHRKTVESALYNSD-SAYLGSRMSEEDIAKTSHAGENEKWKKSLLENRTSERPHETSPKMFSSPIQTHHPLEESEADLEIEMKSSTVNVMAANIPPNSEIQSQLEQLEDAPEVECQPLPFETTLLRAQGTLKKKER-KKELSSHGRVNVFSYGQVKLCSTGFITHVVQREPAKSPETEQLFKNYARPGPVSAQEAFGNRTHHASETPDSSSLTSTLSKESTQPPHKRFCRTNTGYGTENKPVATDDNLALFQGSRKESHTDCFLPDTT-SFPWCRNVSGGYKKKGKVGSF-KHVVRRKLSLRSQIGSLEKFKRQYGKVNNSLAAEEDNDTDFRTHLEPHNEPDVLLKDKSLSDMSDGGEITPSEHSDG---CQPLRPILYPET--LSKED--RLEQRPSLRESPITLAELLHGNRKPSEVKKSTEALASKLSRLK-DSEKEMQTMEMAGPVSERPDSDPSWKDNSQCARLDLNFCELYKNKLEKTESEVLPMPDSAPEDDSINKNSVLCSN-SVTDDREKPETSLLLPCSDSKIS-KDSDVLIRVSEQQSGSPDSASREVTRQVEDSAGSQCGICSQSHGFKARSCSDNEESSTHSMDWQQHFDVTLGRTVYINRMTGLSTFVAP-TDDIQTPCTKDLTTVAVDVLLGNGVQYRCHPFRSDLVLPFLPRAQEERTRRR-HNRDAVD--AAAVSEPLQSLFSEWSNPVFARYPEVAVDVSSGQAGSLAVKIHNVLYPYRFTKEMIHSVQVLQQVDNKFIACLMSSRTDGSGQAEILVGFVGGNLLVLVDQHAAHERVRLEQLITDSYEKQAPQSAGRKKLLSSTIIPPLAITVSEEQRRLLRSYHKHLEDLGLELLFPD--ASDSSILVGKVPLCFVEREANELRRGRSPVTKSIVEELIREQLELLQTTGG------------IQGTLPLTVQKVLASQACHGAIKFNDRLSLEESCRLIEALSLCQLPFQCAHGRPSMLPLADLDHLEQEKQV-KPNLTKLRKMAHAWHLFGKAEGCDTKQEPQQPVPPCEPP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A1Y7VMP7-1", "uniprot_id": "A0A1Y7VMP7_MOUSE", "id": "A0A1Y7VMP7-1", "name": "", "aln": "---MIRCLSDDVKTKLRSGLAISSLGQCVEELTLNSIDAEATCVAIRVNMETFQVQVIDNGLGMAGDDVEKVGNRYFTSKCHSVRDLENPAFYGFRGEALASIADMAGAVEISSKKNTTLKTFVKMFQNGKALAT----------HEADLTRPSVGTTVTVYNLFYQFPVRR---KSMDPRLEFEKVRQRVEALSLMHPSISFSLRNDV-----------SGSMVLQLPKTKDICSRFCQIYG-LGKSQKLREIRFKYKEFEFSGYISSEAHYNKNMQFLFVNRRLVLRTKLHKLIDFLLRKESIICRPKNGSASRQMNSSPRHRSASELHGIYVINVQCPFCEYDVCIEPAKTLIEFQSWDTVLICIQEGVKRFLKQEKLFVELSGEDIKEFNEDNGFSLFGTTLQTHVSTHEKCDQSSFREACNKILDSYEMFNLQSKAVKRIATLENKTRQNPGDSETIRKKTVGSL-YTDASDGPCYSKSVESVLQDSNNSAYLEPRVSEEEVAKTSHSGENEKWKKSFLENKTSGRIHETSPKMFSSPIQMHHLLEEREADLEMQTISSTVNVMAANIPQNNDIPSQLEKWKDAPEVGCQPLPFETTLLRVRGTQRKKERRKKEPSSRGRVNVFSYGQVKLCSTGFITHVVQSEHAKSTETEHSFKNYARPGPVSAQETFGKRTHHAIETPDSSDLTSTLSKESSQPPNKRFCRTNTGYGTENKPVATDDNLALFQESCKESHTDRLLPDAS-SFPWCRYVSDGCRKIDKRGSF-KQVVRRKLSLRSQVGSLEKFKRQYGKVSSSLDTEKDNNTEVRTHLDPQNEPDVLLKDKSHLDMSDGCEITTVEHSET---CQPLSPILYPEKILFSKED--RLEQMPHLRESPITLEELSHCNRK-ADVEKSAASLASKLSKLK-DSEKEMQTVGMTGHTSELPDSNPSWKDNSQCTRLDLDFCELLKNKLEKIESDMLPMADSATEDGPINKNSELHPN-NTTDDTEKPETPLLFPCNDSKIS-RDSDVLIRTSEQPTGNPDSVGKVIMSQVEDGIGSQGGVCPQGDESKARSCSKNE-PNAHCMDWQQHFDVTLGRMVYINRMTGLSTFVAP-TDDLHTACTKDLTTVAVDVLLGNGAQYRCHPFRSDLVLPFLPRAQEERTMLR-HNSNAVDAAAAAVSEPLQSLFSEWSNPVFARYPEVAVDVSSGQAESLAVKIHNVLYPYRFTKEMIHSVKVLQQVDNKFIACLMSTRMDEDGR-------TGGNLLVLVDQHAAHERIRLEQLITDSYEKQDPQSAGRKKLLSSTIIPPLAITVSEEQRRLLRSYHKHLEDLGLELLFPD--ASDSLILVGKVPLCFVEREASELRRGRSTVTKSIVEELIREQVELLQTTGG------------IQGTLPLTVQKVLASQACHGAIKFNDRLSLEESCRLIEALSLSQLPFQCAHGRPSMLPLADLDHLEQEKQV-KPNLAKLRKMVRAWHLFGKTE-----QNLQQPIRPCEPP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UHC1-1", "uniprot_id": "MLH3_HUMAN", "id": "Q9UHC1-1", "name": "DNA mismatch repair protein Mlh3", "aln": "---MIKCLSVEVQAKLRSGLAISSLGQCVEELALNSIDAEAKCVAVRVNMETFQVQVIDNGFGMGSDDVEKVGNRYFTSKCHSVQDLENPRFYGFRGEALANIADMASAVEISSKKNRTMKTFVKLFQSGKALKA----------CEADVTRASAGTTVTVYNLFYQLPVRR---KCMDPRLEFEKVRQRIEALSLMHPSISFSLRNDV-----------SGSMVLQLPKTKDVCSRFCQIYG-LGKSQKLREISFKYKEFELSGYISSEAHYNKNMQFLFVNKRLVLRTKLHKLIDFLLRKESIICKPKNGPTSRQMNSSLRHRSTPELYGIYVINVQCQFCEYDVCMEPAKTLIEFQNWDTLLFCIQEGVKMFLKQEKLFVELSGEDIKEFSEDNGFSLFDATLQKRVTSDERSN---FQEACNNILDSYEMFNLQSKAVKRKTTAENVNTQSSRDSEATRKNTNDAFLYIYESGGPGHSKMTEPSLQNKD-SSCSESKMLEQETIVASEAGENEKHKKSFLEHSSLENPCGTSLEMFLSPFQTPCHFEESGQDLEIWKESTTVNGMAANILKNNRIQNQPKRFKDATEVGCQPLPFATTLWGVHSAQTEKEK-KKESSNCGRRNVFSYGRVKLCSTGFITHVVQNEKTKSTETEHSFKNYVRPGPTRAQETFGNRTRHSVETPDIKDLASTLSKESGQLPNKKNCRTNISYGLENEPTATYTMFSAFQEGSKKSQTDCILSDTSPSFPWYRHVSNDSRKTDKLIGFSKPIVRKKLSLSSQLGSLEKFKRQYGKVENPLDTEVEESNGVTTNLSLQVEPDILLKDKNRLENSDVCKITTMEHSDSDSSCQPASHILNSEKFPFSKDEDCLEQQMPSLRESPMTLKELSLFNRKPLDLEKSSESLASKLSRLK-GSERETQTMGMMSRFNELPNSDSSRKDSKLCSVLTQDFCMLFNNKHEKTENGVIPTSDSATQDNSFNKNSKTHSNSNTTENCVISETPLVLPYNNSKVTGKDSDVLIRASEQQIGSLDSPSGMLMNPVEDATGDQNGICFQSEESKARACSETEESNTCCSDWQRHFDVALGRMVYVNKMTGLSTFIAP-TEDIQAACTKDLTTVAVDVVLENGSQYRCQPFRSDLVLPFLPRARAERTVMRQDNRDTVD--DTVSSESLQSLFSEWDNPVFARYPEVAVDVSSGQAESLAVKIHNILYPYRFTKGMIHSMQVLQQVDNKFIACLMSTKTEENGE-------AGGNLLVLVDQHAAHERIRLEQLIIDSYEKQQAQGSGRKKLLSSTLIPPLEITVTEEQRRLLWCYHKNLEDLGLEFVFPD--TSDSLVLVGKVPLCFVEREANELRRGRSTVTKSIVEEFIREQLELLQTTGG------------IQGTLPLTVQKVLASQACHGAIKFNDGLSLQESCRLIEALSSCQLPFQCAHGRPSMLPLADIDHLEQEKQI-KPNLTKLRKMAQAWRLFGKAE-CDTRQSLQQSMPPCEPP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B931-1", "uniprot_id": "A0A8M2B931_DANRE", "id": "A0A8M2B931-1", "name": "", "aln": "---MIKSLPINVQAQLRSGVAIFSLQQCVEELILNSIDAGATCVAVKIDIEACKLQVIDNGSGMCLEDMEKVGLRYNTSKCSSLEDLDNLHFYGFRGEAISSIVSLAEMVEISSRTKQSVKTYVKSFNETNALEV----------FEAQTVRPSAGTTVSVYNLFHNMPVRR---KRMDPVLETERIRQRVEAISLMHPSVSFTVKKEN-----------SAHMMVQLSKTSSTYYRFVQIHG-LNRAQKLGEVNYEHEQFQITGHIGREGHYNNSLQFLFVNERLLLKTRIHKTLNCLLKRVSGAARQNNSPTSYPVTSSPKQKGGYDLHGIYVINIKCHYSEYDICLEPAKSLIEFKDWDNVLICIEEGVKAFLTKENLVSELN-----TISNDG---------------------------------------LPCSPVRNAESSEKQKRSSEETN-----------------------EACETMIEKND---------------------------------------------------------------------SSVVDVADG--VQMLEQESIYTESDEGKALQSEDLPFQTTLVGAAEINNNHEE----------------DENAVCSN--ISHTDS--------------------PLAVNKNVMGSKSHKISLPEAQDSLQKFYTPNKTSPKKRRMPLN----------DTEEEKHVFYGGPSKT--------------------------------FKATPPRKLTLSFETGSLDKFKRLFGK-----EAEKKQPSTEKTSLLNPNPNDRFVGSTSCLD-------------------DLHHPVLRNSS------------GHPTTHRS----TESSSLNKK------NKISLAAKCSYLKQDKELCRDSNFLKRDLSSFPPSQDSCFKELEKTLLDEDVLFGSSGIVDSVD---FPLIEQDTALPSVAEESHLFNN-----------NVTFFIGNESSVD-----------------------------EASVASQRDPQHSIAGNEGQTTNESVESIPVSNSWLAHYDSWLGKLVYINQVTGLSKYNSPPMEETQVPCTTDVTNMAVSVISKAGFEYRCYPFQSDIVLPFLPKPRAERAFNS--GTDSRE--DAQAPDSLSTLFSEWHNPVFIRPPEVAVDVTSGQAEGLAVKIHNILFPYRFTKNMIHTMRVINQVDKKFLACLINTAGQNTSES----STDEGNLLVLVDQHAAHERVRLEGLIADSYE-DDPDTPGKKRLCSSRVTPPLEINVTEEELRLLRSCQGFLRGLALDVRFPK--SESLSVFLESLPACFIEKESTELRRGRRSVIKTIAEDYLREHIELLRSTGR------------VRGILPLTVHNVLASQACHGAIKFNDVLNKEECCSLVSSLSSCRLPFQCAHGRPSIVPLADLHHLEEQQDIPKPNLKKLRRMYKSWQLYGQNQ------YFAQNKA-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q12083-1", "uniprot_id": "MLH3_YEAST", "id": "Q12083-1", "name": "DNA mismatch repair protein MLH3", "aln": "MSQHIRKLDSDVSERLKSQACTVSLASAVREIVQNSVDAHATTIDVMIDLPNLSFAVYDDGIGLTRSDLNILATQNYTSKIRKMNDLVTMKTYGYRGDALYSISNVSNLFVCSKKKDYNSAWMRKFPSKSVMLSENTILPIDPFWKICPWSRTKSGTVVIVEDMLYNLPVRRRILKEEPPFKTFNTIKADMLQILVMHPMISLNVQYTDKLRINTEVLFRSKNITEGLTKHQQMSQVLRNVFGAIIPPDMLKKVSLKFNEYQIEGIISKMPVGLKDLQFIYINGRRYADSAFQGYVDSLFQAQDFGEKGMSLLKTKSVGKPYRS------HPVFILDVRCPQTIDDLLQDPAKKIVKPSHIRTIEPLIVKTIRSFLTFQGYLTPDK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SDSSFEIVNCSQKTATLPDSRIQISKR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NQVLNSKMKIAR----------------------------------INSYIGKPAVN--------------------------------------------------------------------------------------------------------------------------------GCRINNSTINYEKIKN-------------------------------------------IRIDGQKSRLR----------NKLSSRPYDSGFTEDYD-----------------------SIGKTITDFSISRSVLAKYEVINQVDKKFILIRCLDQSIHNCP-----------LLVLVDQHACDERIRLEELFYSLLTEVVTG------TFVARDLKDCCIEVDRTEADLFKHYQSEFKKWGIGYETIEGTMETSLLEIKTLPEMLTSKYNGDKDYLKMVLLQHAHDLKDFKKLPMDLSHFENYTSVDKLYWWKYSSCVPTVFHEILNSKACRSAVMFGDELTRQECIILISKLSRCHNPFECAHGRPSMVPIAELK------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: * :*. :*:* . ** ..*.*: **:** *. : : ::: .. * *:* *: .*:: :. : *** .:.** . **:**:*: .* .:: . *.:.. . * .. * . *.. **.* * ::::::**** * * : :: : : :*** :*:.:: * : *.* .. : ::.* : .: * :: :.::::: * *. :.:**:::* * : :: :: *:: . : . : : .. : : :::::::* *: :***.::: . .: : : :: **. : . . . . : .. .: .:: * :* . : : . . * . .. : ::: . . .: *:* : .* : : : ::: :: . .*::***:**: *********..**:*** *: . . : * * . : *: : :. .: . . : : .:* : .: : : : : : ::: : : . :* ..:::* *:**:.*: *.* *. :*. *:. ** .: **:*******::*:*::. ", "identical_positions": 122, "similar_positions": 238, "identity": "8.06%" }, { "cls_id": "homologset.agr.RGD:1309228", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5RKH7-1", "uniprot_id": "S35F6_RAT", "id": "Q5RKH7-1", "name": "Solute carrier family 35 member F6", "aln": "MAWTKYQLFLAGLMLVTGSINTLSAKWADNFEAEGCGGSQEHSFKHPFVQAVGMFLGEFSCLAAFYLLKCRARRQSDSS------VEPRQPFNALLFLPPALCDMTGTSIMYVALNMTSASSFQMLRGAVIIFTGLFSVAFLDRRLVPSQWLGILITIAGLVVVGLADLLSKHDSQHKLS-----EVITGDLLIIMAQIIIAIQMVLEEKFVYKHNIHPLQAVGIEGFFGFVILSLLLVPMYYIPTAS-FSGNPRGVLEDALDAFCQVGRQPLIALALLGNISSIAFFNFSGISVTKELSATTRMVLDTLRTVVIWAFTLALGWEVFHPLQILGFLILLMGTALYNG--LHRPLLACLSRRWRHPTQEGEQERLLGDSRTPINETS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VE96-1", "uniprot_id": "S35F6_MOUSE", "id": "Q8VE96-1", "name": "Solute carrier family 35 member F6", "aln": "MAWTKYQLFLAGLMLVTGSINTLSAKWADNFVAEGCGGSQEHSFKHPFVQAVGMFLGEFSCLAAFYLLKCQGRRQSASS------VEPQQPFNTLLFLPPALCDMTGTSIMYVALNMTSASSFQMLRGAVIIFTGLFSVAFLDRRLAPSQWLGILITIAGLVVVGLADLLSKHDSQHKLS-----EVITGDLLIIMAQIIIAIQMVLEEKFVYKHNIHPLQAVGIEGFFGFVILSLLLVPMFYIPTAS-FSGNPRGVLEDALDAFCQVGRQPLIALALLGNISSIAFFNFSGISVTKELSATTRMVLDTLRTIVIWAFTLALGWEIFYPLQILGFLILLMGTALYNG--LHRPLLAFLSRRWRLPTQEGEQERLLGDSRTPINEAS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N357-1", "uniprot_id": "S35F6_HUMAN", "id": "Q8N357-1", "name": "Solute carrier family 35 member F6", "aln": "MAWTKYQLFLAGLMLVTGSINTLSAKWADNFMAEGCGGSKEHSFQHPFLQAVGMFLGEFSCLAAFYLLRCRAAGQSDSS------VDPQQPFNPLLFLPPALCDMTGTSLMYVALNMTSASSFQMLRGAVIIFTGLFSVAFLGRRLVLSQWLGILATIAGLVVVGLADLLSKHDSQHKLS-----EVITGDLLIIMAQIIVAIQMVLEEKFVYKHNVHPLRAVGTEGLFGFVILSLLLVPMYYIPAGS-FSGNPRGTLEDALDAFCQVGQQPLIAVALLGNISSIAFFNFAGISVTKELSATTRMVLDSLRTVVIWALSLALGWEAFHALQILGFLILLIGTALYNG--LHRPLLGRLSR-GRPLAEESEQERLLGGTRTPINDAS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VGF5-1", "uniprot_id": "Q9VGF5_DROME", "id": "Q9VGF5-1", "name": "", "aln": "---MDHRVFLSLIFVLSGTFNVLVVKWANQQQVIGSDG-KLHGFQHPVVFTLLMFLGEFLCFAVFKVIRLISNRRGVISDLDSILSQDSSEFRPVSMLLPTLLDAAASILLFTGLYLTYATSFQMIRGAALIFVGIFSTMFLNHTLTGRHWLAIFTISCGLLDIISLDVHRVEYDLVTLPYTDYKSILTGDLLIIIAEILHGLQYVCEEKQLKTSNVAPLQAAGWQGIFGLGITSMLAICMNFLPSIDPFSCSSRAVFDDWGDLFAALQGSISLIMTLIAFTISCAMYNFIGLYIAMYSSSANRLLADGLRVYFIWVFVIIMEWEYMNLVTIMGFLILQMGIILYRQALFLDWYRAAVARWYRARYVDLGTENAAAPNSRPADVI-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:::**: :::::*::*.* .***:: . *..* : *.*:**.: :: ****** *:*.* ::: . :. * : . *..: :* *:* * :.: :::..* :* *:****:***.:**.*:**. **.: *. :**.*: .**: : *: . . .*. .::*******:*:*: .:* * *** : . *: **:*.* :*:**: * *:* : * ::*: . ** ..*..::* * *. : . : ::*:. * *::** *: :: *::.*:: * **. .**.: : : ** : : *:***** :* **. : . ::* * : *. . . * : ", "identical_positions": 115, "similar_positions": 137, "identity": "29.79%" }, { "cls_id": "homologset.agr.RGD:1309229", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K3K7-1", "uniprot_id": "PLCB_MOUSE", "id": "Q8K3K7-1", "name": "1-acyl-sn-glycerol-3-phosphate acyltransferase beta", "aln": "-MDPWPWLTAALLLLLLLVQLSRTARFYAKVGLYCVLCLSFSAAASIVCLLRHGGR--TVDNMSIISWFVRSFKYVYGLRFEVSGQKKLEVDGPCVIISNHQSILDMMGLMEILP--KRCVQIAKRELMFTGPVGLIMYLGGVYFINRQQARTAMSVMADLGDLMVKENLKVWIYPEGTR--NDNGDLLPFKKGAFYLAIQAQVPIIPVVYSSFSSFYNVKTKLFTSGTIKVQVLDAVPTNGLTDADVTKLVDTCYQSMRATFLQISQIPQENSAIKEPGVLPAQ------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4AC45-1", "uniprot_id": "D4AC45_RAT", "id": "D4AC45-1", "name": "1-acyl-sn-glycerol-3-phosphate acyltransferase", "aln": "-------MGAAG-------RLNRTARFYVKVGLYCVLCLSFSAAASIVCLLRHGGR--TVDNMSIISWFVRSFKYVYGLRFEVSGQKKLEVDGPCVIISNHQSILDMMGLMEILP--KRCVQIAKRELMFTGPVGLIMYLGGVYFINRQQAKTAMSLMADLGDLMVKENLKVWIYPEGTR--NDNGDLLPFKKGAFYLAIQAQVPIIPVVYSSFSSFYNVKTKLFTSGTIRVQVLDAVPTNGLTDADVTKLVDTCYQSMRATFLQISEIPQENSTIKESGVLPAQ------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O15120-1", "uniprot_id": "PLCB_HUMAN", "id": "O15120-1", "name": "1-acyl-sn-glycerol-3-phosphate acyltransferase beta", "aln": "-MELWPCLAAALLLLLLLVQLSRAAEFYAKVALYCALCFTVSAVASLVCLLRHGGR--TVENMSIIGWFVRSFKYFYGLRFEVRDPRRLQEARPCVIVSNHQSILDMMGLMEVLP--ERCVQIAKRELLFLGPVGLIMYLGGVFFINRQRSSTAMTVMADLGERMVRENLKVWIYPEGTR--NDNGDLLPFKKGAFYLAVQAQVPIVPVVYSSFSSFYNTKKKFFTSGTVTVQVLEAIPTSGLTAADVPALVDTCHRAMRTTFLHISKTPQENGATAGSGVQPAQ------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7KTI0-1", "uniprot_id": "Q7KTI0_DROME", "id": "Q7KTI0-1", "name": "1-acyl-sn-glycerol-3-phosphate acyltransferase", "aln": "---MACTCEVIGLACVVALILSATAKAPYQMRMFFIFFGAGLIVFLCVPFMILRPR--DYRNALFPSWCFRQLCRLVGITMEVRGLENVRKDHGAVVIMNHQSAVDLCVLAYLWPVIGRATVVSKKEVLYIPFFGIGAWLWGTLYIDRSRKTDSINSLQKEAKAIQERNCKLLLFPEGTR--NSKDSLLPFKKGSFHIALQGKSPVQPVVISKYS-FMDDEKKTFRPGHALIHILPEVSTEKYKREDVQLLIDECQSIMQTEYTKLSKEGQALSSKKQA------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VYJ4-1", "uniprot_id": "Q9VYJ4_DROME", "id": "Q9VYJ4-1", "name": "1-acyl-sn-glycerol-3-phosphate acyltransferase", "aln": "MITMTSFIELLGLFLLLMLPFLYETNHIFRYYFKFLMYYGIVSFNSIILIPAFLTRPCDVRNLLWASTWCHRVSTLIGLRWELRGKEHLAKDQACIIVANHQSSLDVLGMFNIWHVMNKCTVVAKRELFYAWPFGLAAWLAGLIFIDRVRGEKARETLNDVNRRIKKQRIKLWVFPEGTR--RNTGALHPFKKGAFHMAIDQQIPILPVVFSSYCTFLNDKKKILNSGRIVITTLPPVSTEGLTKDDIDVLMERVRSQMIETFKVTSAEALHRYKPIKKVGIPAASSASTSSTTTTTLASPGTAVTPVADAAVAAAAAVASSSSAYGQPPGYEAGAAKASLLKTL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P33333-1", "uniprot_id": "PLSC_YEAST", "id": "P33333-1", "name": "1-acyl-sn-glycerol-3-phosphate acyltransferase", "aln": "------------------MSVIGRFLYYLRSVLVVLALAGCGFYGVIASILCTLIGKQHLAQWITARCFYHVMKLMLGLDVKVVGEENLAKK-PYIMIANHQSTLDIFMLGRIFP--PGCTVTAKKSLKYVPFLGWFMALSGTYFLDRSKRQEAIDTLNKGLENVKKNKRALWVFPEGTRSYTSELTMLPFKKGAFHLAQQGKIPIVPVVVSNTSTLVSPKYGVFNRGCMIVRILKPISTENLTKDKIGEFAEKVRDQMVDTLKEIGYSPAINDTTLPPQAIEYAALQHDKKVNKKIKNEPVPSVSISNDVNTHNEGSSVKKMH---------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : : : : . . *: :: . ..: ::: **** :*: : : .. :*:.: : .* * * :::* : : : . : ... : ::***** . : *****:*::* : : *: *** *. . : . : : * : * :.*. . .: : : * . ", "identical_positions": 32, "similar_positions": 68, "identity": "9.28%" }, { "cls_id": "homologset.agr.RGD:1309230", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9C0J8-1", "uniprot_id": "WDR33_HUMAN", "id": "Q9C0J8-1", "name": "pre-mRNA 3' end processing protein WDR33", "aln": "----------------MATEIGS-PPRFFHMPRFQHQAPRQLFYKR----------PDFAQQQAMQQLTFDGKRMRKAVNRKTIDYNPSVIKYLENRIWQRDQRDMRAIQPDAGYYNDLVPPIGMLN-NPMNAVTTKFVRTSTNKVKCPVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTADHGGYVKYWQSNMNNVKMF-QAHKEAIREASFSPTDNKFATCSDDGTVRIWDFLRCHEERILRGHGADVKCVDWHPTKGLVVSGSKDSQQPIKFWDPKTGQSLATLHAHKNTVMEVKLN-LNGNWLLTASRDHLCKLFDIRNLKEELQVFRGHKKEATAVAWHPVHEGLFASGGSDGSLLFWHVG--VEKEVGGMEMAHEGMIWSLAWHPLGHILCSGSNDHTSKFWTRNRPGDKMRDRYNLNLLPG--MSEDGVEYDDLEPNSLAVIPGMGIPEQLKLAMEQEQMGKDESNEIEMTIPGLDWGMEEVMQKDQKKVPQKKVPYAKPIPAQFQQAWMQNKVPIPAPNEVLNDRKEDIKLEEKKKTQAEIEQEMATLQYTNPQLLEQLKIERLAQKQVEQIQPPPSSGTPLLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGPPGPRENQGPAPQGMIMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSMLGPPQELRGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQSTGPPPLIPGLGQQGAQGRIPPLNPGQGPGPNKGDSRGPPNHHMGPMSERRHEQSGGPEHGPERGPFRGGQDCRGPPDRRGPHPDFPDDFSRPDDFHPDKRFGHRLREFEGRGGPLPQEEKWRRGGPGPPFPPDHREFSEGDGRGAARGPPGAWEGRRPGDERFPRDPEDPRFR---GRREESFR-RGAPPRHEGRAPP--RGRDGFPGPEDFGPEENFDASEEAARGRDLRG---RGRGTPRGG-RKGLLPTPDEFPRFEGGRKPDSWDGNREPGPGHEHFRDTPR--PDHPPHDGHSPASRERSSSLQGMDMASLPPRKRPWHDGPGTSEHREMEAPGGPSEDRGGKGRGGPGPAQRVPKSG--RSSSLDGEHHDGYHRDEPFGGPPGSGTPSRGGRSGSNWGRGSNMNSGPPRRGASRGGGRGR---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8K4P0-1", "uniprot_id": "WDR33_MOUSE", "id": "Q8K4P0-1", "name": "pre-mRNA 3' end processing protein WDR33", "aln": "----------------MATEIGS-PPRFFHMPRFQHQAPRQLFYKR----------PDFAQQQAMQQLTFDGKRMRKAVNRKTIDYNPSVIKYLENRIWQRDQRDMRAIQPDAGYYNDLVPPIGMLN-NPMNAVTTKFVRTSTNKVKCPVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTADHGGYVKYWQSNMNNVKMF-QAHKEAIREASFSPTDNKFATCSDDGTVRIWDFLRCHEERILRGHGADVKCVDWHPTKGLVVSGSKDSQQPIKFWDPKTGQSLATLHAHKNTVMEVKLN-LNGNWLLTASRDHLCKLFDIRNLKEELQVFRGHKKEATAVAWHPVHEGLFASGGSDGSLLFWHVG--VEKEVGGMEMAHEGMIWSLAWHPLGHILCSGSNDHTSKFWTRNRPGDKMRDRYNLNLLPG--MSEDGVEYDDLEPNSLAVIPGMGIPEQLKLAMEQEQMGKDESSEIEMTIPGLDWGMEEVMQKDQKKVPQKKVPYAKPIPAQFQQAWMQNKVPIPAPNEVLNDRKEDIKLEEKKKTQAEIEQEMATLQYTNPQLLEQLKIERLAQKQADQIQPPPSSGTPLLGPQPFSGQGPISQIPQGFQQPHPSQQMPL-VPQMGPPGPQGQFRAPGPQGQMGPQGPPMHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPASQGHMGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPASQGIQG-----PLMGLNPRGMQGPPGPRENQGPAPQGLMIGHPPQEMRGPHPPSGLLGHGPQEMRGPQEMRGMQGPPPQGSMLGPPQELRGPSGSQGQQGPPQGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGPIPFQQQKAPLLGDGPRAPFNQEGQSTGPPPLIPGLGQQGAQGRIPPLNPGQGPGPNKGDTRGPPNHHLGPMSERRHEQSGGPEHGPDRGPFRGGQDCRGPPDRRGSHPDFPDDF-RPDDFHPDKRFGHRLREFEGRGGPLPQEEKWRRGGPGPPFPPDHREFNEGDGRGAARGPPGAWEGRRPGDDRFPRDPDDPRFR---GRREESFR-RGAPPRHEGRAPP--RGRDNFPGPDDFGPEEGFDASDEAARGRDLRG---RGRGTPRGGSRKCLLPTPDEFPRFEGGRKPDSWDGNREPGPGHEHFRDAPR--PDHPPHDGHSPASRERSSSLQGMDMASLPPRKRPWHDGSGTSEHREMEAQGGPSEDRGSKGRGGPGPSQRVPKSG--RSSSLDGDHHDGYHRDEPFGGPPGSSSSSRGARSGSNWGRGSNMNSGPPRRGTSRGSGRGR---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0M1Z4-1", "uniprot_id": "A0ABK0M1Z4_RAT", "id": "A0ABK0M1Z4-1", "name": "pre-mRNA 3' end processing protein WDR33", "aln": "----------------MATEIGS-PPRFFHMPRFQHQAPRQLFYKR----------PDFAQQQAMQQLTFDGKRMRKAVNRKTIDYNPSVIKYLENRIWQRDQRDMRAIQPDAGYYNDLVPPIGMLN-NPMNAVTTKFVRTSTNKVKCPVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTADHGGYVKYWQSNMNNVKMF-QAHKEAIREASFSPTDNKFATCSDDGTVRIWDFLRCHEERILRGHGADVKCVDWHPTKGLVVSGSKDSQQPIKFWDPKTGQSLATLHAHKNTVMEVKLN-LNGNWLLTASRDHLCKLFDIRNLKEELQVFRGHKKEATAVAWHPVHEGLFASGGSDGSLLFWHVG--VEKEVGGMEMAHEGMIWSLAWHPLGHILCSGSNDHTSKFWTRNRPGDKMRDRYNLNLLPG--MSEDGVEYDDLEPNSLAVIPGMGIPEQLKLAMEQEQMGKDESNDIEMTIPGLDWGMEEVMQKDQKKVPQKKVPYAKPIPAQFQQAWMQNKVPIPAPNEVLNDRKEDIKLEEKKKTQAEIEQEMATLQYTNPQLLEQLKIERLAQKQADQIQPPPSSGTPLLGPQPFSGQGPMSQIPQGFQQPHPSQQMPL-VAQMGPPGPQGQFRAPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPAPQGHMGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPTSQGIQG-----PLMGLNPRGMQGPPGPRENQGPAPQGIMIGHPPQEMRGPHPPSGLLGHGPQEMRGPQEMRGMQGPPPQGSMLGPPQELRGPSGSQGQQGPPQGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGPIPFQQQKAPLLGDGPRAPFNQEGQSTGPPPLIPGLGQQGAQGRIPPLNPGQGPGPNKG-TKGRRERHASGLPSPPGLVATTTTSPFVVVTLEALPTITWAPCQRG---GMSRAVVLSMVLTGDLSGVARTAGVLLTGVALTLISLMTSADQMTSILTSALATGYGNSRDEEDPYHKKKSGGEGALDLPFHLITGSSMRGTAGVQPEALQGHGKAADLETNDSPGILMTHDFEGAEKKALEEVLPQDTKAVLLQEEGTTFLVLMTLVQKRFSMLLMKQPEDEISEVEAVAPLEGDPGSAYSPLLMSFLALKEDGSQTPGMETESPDQVMNTFVMLPVLIIPLTMAIHQLAESAPLLSKAWTWPPYHPGSAPGMMGRALLNTERWRPKEAPRRTEEAKAEGAQDLPREFQNPGVPALWTETIMMDTTEMNLLVALQAAAHLLEGAGVAVTGVEGVT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VNG2-1", "uniprot_id": "Q9VNG2_DROME", "id": "Q9VNG2-1", "name": "", "aln": "MDVSQPPPQLLTAPSALATNFTSLPPPNMGGQHYRHYHPHHGSNKHGYNQFKPFMPGGFQRPFGMSQDDFDGKRLRKSVMRKTVDYNASIIKALENRLYQRDYRDRLALQPDSIYVPHMLPPSAYLD-NPSNAVTTRFVKTATNKMRCPIFTLAWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDISVRTMVWSHNDSWMVTGDHGGYVKYWQSNMNNVKMY-QAHKEAIRGISFSPTDSKFVSGSDDGTLRIWDFMRCQEERVLRGHGADVKCVHWHPQKGMIVSGSKDNQQPIKIWDPKSGIALATLHAHKSTVMDLKWN-DNGNWLVTASRDHLLKLFDIRNLREEVQVFRGHKKEASSVSWHPIHEGLFCSGGSDGSILFWNVG--TDKEIGCVETAHDSIVWTLAWHPLGHILCSGSNDHTIKFWTRNRPGDLMRDKYNLNTLPASLAALDECEYDD------AIIPGMGPEDRVEFTES---LTADKG-----FIPGLDLDPSKAINDRDR---EKKVPYSKPIPRNFQVNWAG---PRRADDPSVLSIHEELAAREAKDTTNGLN---------HQQISENTMEGILASGMLNGLDPQTIVGVLVYN---------------RFIRVHPDSRLMA----------------------------AIRQGAEFLNKYIDAG-------KLEELNDVVPVRDRSRSVSPT--------------VEARGEMVS--------------PPTKKSRFEPR-----------------QHNAQLVCVR---------------ELMQCKKPFLQSLVAAKAQQ---PNTEFVDEPPLEQR----------DRDREREGDRDR----------------ERERARERERDQSGGRPNPWASNAPWSNNGNPG--GNGNGSNG-FSNNGAESFNDRDRGGGGQRRRRGINNSGPGNG--------GGSGGGG-------GGGSGRNRGRNNNRRY-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P42841-1", "uniprot_id": "PFS2_YEAST", "id": "P42841-1", "name": "Polyadenylation factor subunit 2", "aln": "-----------------------------------MDGHNQNQYQN----------------QNQIQQSQQPPLKKYVTQRRSVDVSSPYINLYYN---RRHGLPNLVVEPETSYTIDIMPPNAYRGRDRVINLPSKFTHLSSNKVKHVIPAIQWTPEGRRLVVATYSGEFSLWNASSFTFETLMQAHDSAVTTMKYSHDSDWMISGDADGMIKIWQPNFSMVKEIDAAHTESIRDMAFSSNDSKFVTCSDDNILKIWNFSNGKQERVLSGHHWDVKSCDWHPEMGLIASASKDN--LVKLWDPRSGNCISSILKFKHTVLKTRFQPTKGNLLMAISKDKSCRVFDIRYSMKELMCVR-DETDYMTLEWHPINESMFTLACYDGSLKHFDLLQNLNEPILTIPYAHDKCITSLSYNPVGHIFATAAKDRTIRFWTRARPIDPN--AYDDPTYNN------------------------------------------------KKINGWFFG----INNDINAVREKSEFGAAPPP------------PATLEPHALPNMNGFINKKPRQE----------------------------IPGIDSNIKSSTLPGLSI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: :. * : : . *:::* ... *: * :*. .::*:: * .::** . . : :.::*.: ::**:: : .: *********..: ****:***. :*.***::**** .* :* :**:. **::.* .* :* **.*:. ** **.*:** :**..*.**.: ***. ::**:* . ::**:* ** ***. .*** *::.*.***. :*:***::* .:::: .* **:. : : :** *:: *:*: ::**** :*: .* .:.: :: ***::*.:* . ***: .:.: :: : : **: : :*:::*:***:.:.::*:* :**** ** * *: * * . ::. . :*. : * * * : . : : . :. . :.. . * : ", "identical_positions": 134, "similar_positions": 166, "identity": "9.66%" }, { "cls_id": "homologset.agr.RGD:1309231", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9BV81-1", "uniprot_id": "EMC6_HUMAN", "id": "Q9BV81-1", "name": "ER membrane protein complex subunit 6", "aln": "MAAVVAKREGP---PFISEAAVRGNAAVLDYCRTSVSALSGATAGILGLTGLYGFIFYLLASVLLSLLLILKAGRRWN-KYFKS-RRPLFTGGLIGGLFTYVLFWTFLYGMVHVY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9CQW0-1", "uniprot_id": "EMC6_MOUSE", "id": "Q9CQW0-1", "name": "ER membrane protein complex subunit 6", "aln": "MAAVVAKREGP---PFISEAAVRGNAAVLDYCRTSVSALSGATAGILGLTGLYGFIFYLLASVLLSLLLILKAGRRWN-KYFKS-RRPLFTGGLIGGLFTYVLFWTFLYGMVHVY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4ABX9-1", "uniprot_id": "D4ABX9_RAT", "id": "D4ABX9-1", "name": "ER membrane protein complex subunit 6", "aln": "MAAVVAKREGP---PFISEAAVRGNAAVLDYCRTSVSALSGATAGILGLTGLYGFIFYLLASVLLSLLLILKAGRRWN-KYFKS-RRPLFTGGLIGGLFTYVLFWTFLYGMVHVY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P0F0-1", "uniprot_id": "EMC6_DANRE", "id": "Q6P0F0-1", "name": "ER membrane protein complex subunit 6", "aln": "MASVAAKREGP---QFISEVSVRGNGAVLDYCRTSVSALSGATAGILGLTGLYGFVFYFLASFLLSLLLILKAGRRWN-KCFKS-RRLLFTGGLVGGLFTYVLFWTFLYGMVHVY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VBZ8-1", "uniprot_id": "Q9VBZ8_DROME", "id": "Q9VBZ8-1", "name": "ER membrane protein complex subunit 6", "aln": "MNRVKTTQSKTGEIIAYSEGAIRNNISAVEYCRTSMAAISGCAAGILGLSGTLGFLFYFLSVFVLWILVLVKSGTQWR-KFFIN-RRNLLTNQFMGGLCTYVLFWTFLYGMVHVY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12431-1", "uniprot_id": "EMC6_YEAST", "id": "Q12431-1", "name": "ER membrane protein complex subunit 6", "aln": "MSSNEEVFTQIN-----ATANVVDNKKRLLFVQDSSALVLGLVAGFLQIESVHGFIWFLILYNLINVIYIVWICQLQPGKFYQSPLHDIFFESFFREITGFVMAWTFGYALIG--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : : .* : : : * : : * .**:* : . **::::: :: :: :: * : . : :: :. : :*: *** *.:: ", "identical_positions": 15, "similar_positions": 36, "identity": "13.04%" }, { "cls_id": "homologset.agr.RGD:1309232", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BWQ5-1", "uniprot_id": "DCLK3_MOUSE", "id": "Q8BWQ5-1", "name": "Serine/threonine-protein kinase DCLK3", "aln": "MPAAPVLRPPPPPATPAPPAPSRPAPPIPGHRGPCDHSLKCLSSKISERKLPGPWLPAGRGPLEKPVLGPRGAVMPLFSPQSSLHSVRAEHSPLKPRVVTVVKLGGQPLRKATLLLNRRSVQTFEQLLSDISEALGFPRWKNDRVRKLFTLKGREVKSVSDFFREGDAFIAMGKEPLTLKSIQLAMEELYP-KNRALALAPHSRVPSPRLRSRLPSKLLKGSHRCGEAG---SYSAEMESKAVSRHQGKTSTVLAPEDKARAQK-WVRGKQESEPGGPPSPGAATQEETHASGEKHLGVEIEKTSGEIVRCEKCKRERELQLGLQREPCPLGTSELDLGRAQKRDSEKLVRTKSCRRPSEAKSTDGEEGWKGDSHRGSPRDPPQELRRPNSNSDKKEIRGSESQDSHPQGAPKAQKDLVEGPPAVEEGPIDMRREDRHTCRSKHAAWLRREQQAEPPQLPRTRGEEKQAEHEKKPGGLGERRAP---------EKESKRKLEEKRPERPSGRKPRPKGIISADVEKHYDIGGVIGDGNFATVKECRHRETKQAYAMKMIDKSQLKGKEDIVDSEILIIQSLSHPNIVKLHEVYETEAEIYLIMEYVQGGDLFDAIVENVKFPEPEAAVMITDLCKALVHMHDKNIVHRDVKPENLLVQRNEDKSITLKLADFGLAKYVVRPIFTVCGTPTYVAPEILSEKGYGLEVDMWAAGVILYILLCGFPPFRSPERDQDELFNIIQVGQFEFLSPYWDNISDAAKDLVRNLLEVDPKKRYTAEQVLQHPWIEMVGHTNTGNSQKEESPNS----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1LWF2-1", "uniprot_id": "F1LWF2_RAT", "id": "F1LWF2-1", "name": "non-specific serine/threonine protein kinase", "aln": "MPAAPVLRPPPPPATPAPPAPSRPAPAISGHRGPCDHSLKCLSSKISERKLPGSWLPSGRGPLEKPVLGPRGAVMPMFSPQSSLHSVRAEHSPLKPRVVTVVKLGVQPLRKATLLLNRRSVQTFEQLLSDISEALGFPRWKNDRVRKLFTLKGREVKSVSDFFREGDAFIAMGKEPLTLKSIQLAMEELYP-KNRALALAPHSRVPSPRLRSRLPSKLLKGSHRCGEAG---SYGEVMGNKAVIRHQGKTSTELAPEDKARAQKKWVGGKQESENGGLPSPREATQEETHASGEKHLGVEIEKTSGEIVRCEKCKRETELQLGLQRGQCPPGTSELDLGRGQKRDSEKLVRTKSCRRASEAKSTDGEEGWKGDSHRGSPRDPPQELRRPNNNSDKKESRGSEAQESHPQGVAKAQKDLMEGLPAVEEGAVDARRDSRHTCRIKHAAWLRREQQAEPPQLPRTRGEEKEAEHEKKSGGLGGRRML---------EKESKTKPEENRPERPSGRKLRPTGIISADVEKHYDIGRVIGDGNFAIVKECKHRETRQAYAMKIIDKSQLKGKEDIVDSEILIIQSLSHPNIVKLHEVYETEAEIYLIMEYVQGGDLFDAIIESVKFPEPDAAVMITDLCKALVHMHDKKIVHRDLKPENLLVQRNEDKSTTLKLADFGLAKHVVRPIFTVCGTPTYVAPEILSEKGYGLEVDMWAAGVILYILLCGFPPFRSPERDQDELFNIIQLGQFEFLSPYWDNISDAAKDLVRNLLVVDPKKRYTAHQVLHHPWIGMVGHPSTVNPQKEESPSSEGRFQSQHKKVAEHVS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9C098-1", "uniprot_id": "DCLK3_HUMAN", "id": "Q9C098-1", "name": "Serine/threonine-protein kinase DCLK3", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGKEPLTLKSIQVAVEELYPNKARALTLAQHSRAPSPRLRSRLFSKALKGDHRCGETETPKSCSEVAGCKAAMRHQGKIPEELSLDDRARTQKKWGRGKWEPEPSSKP-PREATLEERHARGEKHLGVEIEKTSGEIIRCEKCKRERELQQSLERERLSLGTSELDMGKGPMYDVEKLVRTRSCRRSPEANPASGEEGWKGDSHRSSPRNPTQELRRPSKSMDKKEDRGPEDQESHAQGAAKAKKDLVEVLPVTEEGLREVKKDTRPMSRSKHGGWLLREHQAGFEKLRRTRGEEKEAEKEKKPCMSGGRRMTLRDDQPAKLEKEPKTRPEENKPERPSGRKPRPMGIIAANVEKHYETGRVIGDGNFAVVKECRHRETRQAYAMKIIDKSRLKGKEDMVDSEILIIQSLSHPNIVKLHEVYETDMEIYLILEYVQGGDLFDAIIESVKFPEPDAALMIMDLCKALVHMHDKSIVHRDLKPENLLVQRNEDKSTTLKLADFGLAKHVVRPIFTVCGTPTYVAPEILSEKGYGLEVDMWAAGVILYILLCGFPPFRSPERDQDELFNIIQLGHFEFLPPYWDNISDAAKDLVSRLLVVDPKKRYTAHQVLQHPWIETAGKTNTVKRQKQVSPSSEGHFRSQHKRVVEQVS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ************:*:***** * ***:** ***.********* ** ***.*****: * . **. ***** . *: :*:**:** * ** *.* .. * * ** ** ** ****************:******** *** .*:* . ******:*:. * ******:****..**:.:.***********.***:*.******... **** **.* *:**.**..**:***:* *..*** : ::: * .* **..** **:** :* *******:**:***. * ** ***.* : **::******** ** ***:*:*****: * ******** ****:****:******:****:******:*************************: *****:************:*.******:**:** ************.*****:************** ***********:***************************************************************:*:****.************** .** *********.***:**** .*:..* : **: **.* ", "identical_positions": 451, "similar_positions": 91, "identity": "55.0%" }, { "cls_id": "homologset.agr.RGD:1309233", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P84103-1", "uniprot_id": "SRSF3_HUMAN", "id": "P84103-1", "name": "Serine/arginine-rich splicing factor 3", "aln": "MHR-DSCPLDCKVYVGNLGNNGNKTELERAFGYYGPLRSVWVARNPPGFAFVEFEDPRDAADAVRELDGRTLCGCRVRVELSNGEKRSRNRGPPPSWGR---------------------RPRD---DYRRRSPPPRRRS-PRRRSFSRSRSRSLSRDRRRERSLSRERNHKPSRSFSRSRSRSRSNERK---------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P84104-1", "uniprot_id": "SRSF3_MOUSE", "id": "P84104-1", "name": "Serine/arginine-rich splicing factor 3", "aln": "MHR-DSCPLDCKVYVGNLGNNGNKTELERAFGYYGPLRSVWVARNPPGFAFVEFEDPRDAADAVRELDGRTLCGCRVRVELSNGEKRSRNRGPPPSWGR---------------------RPRD---DYRRRSPPPRRRS-PRRRSFSRSRSRSLSRDRRRERSLSRERNHKPSRSFSRSRSRSRSNERK---------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6A2P1-1", "uniprot_id": "A0A8I6A2P1_RAT", "id": "A0A8I6A2P1-1", "name": "Serine/arginine-rich splicing factor 3", "aln": "MHR-DSCPLDCKVYVGNLGNNGNKTELERAFGYYGPLRSVWVARNPPGFAFVEFEDPRDAADAVRELDGRTLCGCRVRVELSNGEKRSRNRGPPPSWGR---------------------RPRD---DYRRRSPPPRRRS-PRRRSFSRSRSRSLSRDRRRERSLSRERNHKPSRSFSRSRSRSRSNERK---------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "M9MS48-1", "uniprot_id": "M9MS48_DROME", "id": "M9MS48-1", "name": "", "aln": "MPRYREWDLACKVYVGNLGSSASKYEIENAFSKYGPLRNVWVARNPPGFAFVEFEDRRDAEDATRGLDGTRCCGTRIRVEMSSGRSREGRGGGGGGGGGGGGSGGGGRGGGSGARAGGGGRAGDGGGRYRIKSSSSTTTSTTRTTTTTTSIIIIIMIIKRTTKKKEKTTTATTTRTSTTPLPSTTTTKRTTTTATTRTTSTTADPAPPITHISPTTTTTTATTTPPPCNNNLLCGPNQKFNKFDIFR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q02427-3", "uniprot_id": "RBP1_DROME", "id": "Q02427-3", "name": "RNA-binding protein 1", "aln": "MPRYREWDLACKVYVGNLGSSASKHEIEGAFAKYGPLRNVWVARNPPGFAFVEFEDRRDAEDATRALDGTRCCGTRIRVEMSSGRSRDRRRGEGGSSG----------------------RSGS--GRYRITPS-------ARTTSTATSSFYNINNLQQQP--------------SSQPQPATFNLQL----------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * . * *********....* *:* **. *****.***************** *** **.* *** ** *:***:*.*..*. . * . * *. . ** .. .* : : * : :: : . . : . : ", "identical_positions": 64, "similar_positions": 33, "identity": "25.91%" }, { "cls_id": "homologset.agr.RGD:1309235", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4A586-1", "uniprot_id": "D4A586_RAT", "id": "D4A586-1", "name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related", "aln": "-MSHGPRQPGAATAPAGGKTPGQHGAFVVAVKQERSEGPRAGEKGPQEEEPVKKRG-----WPKGKKRKKILPNGPKAPVTGYVRFLNERREQIRTRHPDLPFPEITKMLGAEWSKLQPAEKQRYLDEAEKEKQQYLKELWAYQQSEAYKVCTEKIQENKIKKEDSS---------SGLMNTLLNGHKGVDCG------------------------------------------DGFSTFDVPIFTEEFLDQNKAREAELRRLRKMNVAFEEQNAVLQRHTQSMNSARERLEQELALEERRTLALQQQLQAVRQALTASFASLPVPGAQPRPQLWARPQPRARPQDVLLGPAPIPRQAPLPQYLSHLPDADLPVARTGETPTLGTLDFYMARLHGAIERDPAQHERLIARVKEILARVASEHL---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z104-1", "uniprot_id": "HM20B_MOUSE", "id": "Q9Z104-1", "name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related", "aln": "-MSHGPRQPGAATAPAGGKTPGQHGAFVVAVKQERSEGSRAGEKGPQEEEPVKKRG-----WPKGKKRKKILPNGPKAPVTGYVRFLNERREQIRTRHPDLPFPEITKMLGAEWSKLQPAEKQRYLDEAEKEKQQYLKELWAYQQSEAYKVCTEKIQENKIKKEDSS---------SGLMNTLLNGHKGVDC-------------------------------------------DGFSTFDVPIFTEEFLDQNKAREAELRRLRKMNVAFEEQNAVLQRHTQSMSSARERLEQELALEERRTLALQQQLQAVRQALTASFASLPVPG-------------------------------------------------TGETPTLGTLDFYMARLHGAIERDPAQHERLIARVKEILARVASEHL---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P0W2-1", "uniprot_id": "HM20B_HUMAN", "id": "Q9P0W2-1", "name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related", "aln": "-MSHGPKQPGAAAAPAGGKAPGQHGGFVVTVKQERGEGPRAGEKGSHEEEPVKKRG-----WPKGKKRKKILPNGPKAPVTGYVRFLNERREQIRTRHPDLPFPEITKMLGAEWSKLQPTEKQRYLDEAEREKQQYMKELRAYQQSEAYKMCTEKIQEKKIKKEDSS---------SGLMNTLLNGHKGGDC-------------------------------------------DGFSTFDVPIFTEEFLDQNKAREAELRRLRKMNVAFEEQNAVLQRHTQSMSSARERLEQELALEERRTLALQQQLQAVRQALTASFASLPVPG-------------------------------------------------TGETPTLGTLDFYMARLHGAIERDPAQHEKLIVRIKEILAQVASEHL---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W2K8-1", "uniprot_id": "Q9W2K8_DROME", "id": "Q9W2K8-1", "name": "", "aln": "MTEPTSKTPDAVPESPVSLPIASQSMDTATIEDFDEDKPAKGKKKAKNPKGRHSDSDIGSELKKLAQRRINVAGAPKMPLNGYVRFMNDRREELRREQPQRTALEHTRIIGEEWHQLPEERKLPYIEAAAKDKAIYQEQLQMFLKEHPEIVANELAKAKKATKLDGSPKEKTPKGESALGKAKKTKAKPVKRQSEDPDDVPLAKVKRAQTPPPPTPPAAPVQPPPSSVPPATPAPRPLQPGEIPIYTNEFIEHNRSTENELRTLRKAKTDLEQQNAVLEQHVDNTKAGYAKVMGEVTELMEENQRLETYLRALRQKLVAALGGISMPP------------------------------------------------LEPSGPSVGNIDKYIRHLAGLVTQ---PSNVTLIKAREALRKVDTSSLLKP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .: *.*.. .. . . ..:. ..:::: : . *:* .:: : :. . * :*: :...** *:.*****:*:***::* .:*: . * *:::* ** :* .* *:: * ::* * ::* : :... :..* : :* .* *.* *.* :: . * . :.. ::**:*:**:::*:: * *** *** :. :*:*****::*.:. .:. :: *:: ... *: *:*:** *.*::..:.:* . *::*.:* *: :* * : : : : : :* * :* :. * ", "identical_positions": 79, "similar_positions": 132, "identity": "18.5%" }, { "cls_id": "homologset.agr.RGD:1309236", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZIC9-1", "uniprot_id": "D3ZIC9_RAT", "id": "D3ZIC9-1", "name": "", "aln": "MLLGLRPCLLRPGPLPLAGSGRGRGGEEPAGPGLVGTRWRAMADLTLCAFLTKVLCAHGGRMFLQDLRGHVELSEAKLRAVLRRAGPERFLLQEVELRDGPWDPEAEVAAGSGSGSGSGSGGGATACRVMAVSSARLCARYQRGECQACDQLHLCRRHMLGKCPHRDCWSTCSLSHDIHTPVNVQVLKNQGLFGLNEAQLRILLLQNDPCLFPEVCLLYNKGGDVLYGYCNLKDKCNKFHVCRSFVRGECTFQTCKRSHQLIHAATLKLLEDQELSVSSVVNFQIISTYRHKKLHKMLEEKDNS-TSTEQSQGLGKQGTPGAGAVEARPFFPARAQSPWKPQ------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BFR1-1", "uniprot_id": "ZCCHL_MOUSE", "id": "Q8BFR1-1", "name": "Zinc finger CCCH-type antiviral protein 1-like", "aln": "-----------------------------------------MADLTLCAFLTKVLCAHGGRMFLQDLRGHVELSEAKLRAVLRRAGPERFLLQEVELRDGPWDAEAEVAAGEG--AGAGSGGGATACRVMAVSSARLCARYQRGECQGCDQLHLCRRHMLGKCPHRDCWSTCSLSHDIHTPINVQVLKSRGLFGLNEGQLRILLLQNDPCLFPEVCQMYNKGVDVLYGYCSLKDRCNKFHVCKSFVRGECPFQPCKRSHQLIHAATLKLLEDQELSVSSVVNFQIISVYRHKKLHKMLEEKDHS-ASTEQPQGLGKQG--ALGAVEARPFLPARAQSPRKPQ------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96H79-1", "uniprot_id": "ZCCHL_HUMAN", "id": "Q96H79-1", "name": "Zinc finger CCCH-type antiviral protein 1-like", "aln": "-----------------------------------------MAEPTVCSFLTKVLCAHGGRMFLKDLRGHVELSEARLRDVLQRAGPERFLLQEVETQEGLGDAEAEAAAGAVG------GGGTSAWRVVAVSSVRLCARYQRGECQACDQLHFCRRHMLGKCPNRDCWSTCTLSHDIHTPVNMQVLKSHGLFGLNENQLRILLLQNDPCLLPEVCLLYNKG-EALYGYCNLKDKCNKFHVCKSFVKGECKLQTCKRSHQLIHAASLKLLQDQGLNIPSVVNFQIISTYKHMKLHKMLENTDNSSPSTEHSQGLEKQGVHAAGAAEAGPLASVPAQSAKKPCPVSCEK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **: *:*:***************:***********:** **:************* ::* *.***.*** ***::* **:****.************.*****:**********:*******:********:*:****.:******* *************:**** :**** :.*****.***:*******:***:*** :*.***********:****:** *.:.*********.*:* *******:.*:* .***:.*** *** . **.** *: .. ***. ** ", "identical_positions": 219, "similar_positions": 51, "identity": "62.93%" }, { "cls_id": "homologset.agr.RGD:1309237", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZCM7-1", "uniprot_id": "D3ZCM7_RAT", "id": "D3ZCM7-1", "name": "", "aln": "MFPQ-SRHPTPHQAAGQ-PFKFTIPESLDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYVMYYEMSYGLNIEMHKQTEIAKRLNTICAQVIPFLSQEHQQQVAQAVERAKQVTMAELNAIIGQQQLQ--AQHLSHGHGPPVP-LTPHPSGLQPPGIPPLGGSASLLALSSALSGQSHLAIKDDKKHHDAERHRGERPGN-NSLLVPDSLRGTDKRRNGPEFSSDIKKRKVDDKD--NYDSDGDKSDDNLVVDVSNEDPSSPHASPTHSPRENGIDKNRLLKKDASGSPASTASSGSSSSLKSKEVNLHEKANTPVLKSSTPTPRSDMPTPGTSATPGLRPGLGKPPAMEPLVNQAAAGLRTPLAVPGPYPAPFGMVPHAGMNGELTSPGAAYAGLHSMSPQMSAAAAAAAAAVVAYGRSPMVGFDPPPHMRVPSIPPNLAGIPGGKPAYSFHVTADGQMQPVPFPPDALIGPGIPRHARQINTLNHGEVVCAVTISNPTRHVYTGGKGCVKVWDISHPGNKSPVSQLDCLNRDNYIRSCKLLPDGCTLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMESSNVEVLHVNKPDKYQLHLHESCVLSLKFAYCGKWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISVDDKYIVTGSGDKKATVYEVIY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62440-1", "uniprot_id": "TLE1_MOUSE", "id": "Q62440-1", "name": "Transducin-like enhancer protein 1", "aln": "MFPQ-SRHPTPHQAAGQ-PFKFTIPESLDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYVMYYEMSYGLNIEMHKQTEIAKRLNTICAQVIPFLSQEHQQQVAQAVERAKQVTMAELNAIIGQQQLQ--AQHLSHGHGPPVP-LTPHPSGLQPPGIPPLGGSASLLALSSALSGQSHLAIKDDKKHHDAERHRDRESGTSNSLLVPDSLRSTDKRRNGPEFSSDIKKRKVDDKD--NYDSDGDKSDDNLVVDVSNEDPSSPHASPTHSPRENGIDKNRLLKKDASGSPASTASSGSSSSLKSKEVSLHEKANTPVLKSSTPTPRSDMPTPGTSATPGLRPGLGKPPAMEPLVNQAAAGLRTPLAVPGPYPAPFGMVPHAGMNGELTSPGAAYAGLHSMSPQMSAAAAAAAAAVVAYGRSPMVGFDPPPHMRVPSIPPNLAGIPGGKPAYSFHVTADGQMQPVPFPPDALIGPGIPRHARQINTLNHGEVVCAVTISNPTRHVYTGGKGCVKVWDISHPGNKSPVSQLDCLNRDNYIRSCKLLPDGCTLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMESSNVEVLHVNKPDKYQLHLHESCVLSLKFAYCGKWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISVDDKYIVTGSGDKKATVYEVIY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q04724-1", "uniprot_id": "TLE1_HUMAN", "id": "Q04724-1", "name": "Transducin-like enhancer protein 1", "aln": "MFPQ-SRHPTPHQAAGQ-PFKFTIPESLDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYVMYYEMSYGLNIEMHKQTEIAKRLNTICAQVIPFLSQEHQQQVAQAVERAKQVTMAELNAIIGQQQLQ--AQHLSHGHGPPVP-LTPHPSGLQPPGIPPLGGSAGLLALSSALSGQSHLAIKDDKKHHDAEHHRDREPGTSNSLLVPDSLRGTDKRRNGPEFSNDIKKRKVDDKDSSHYDSDGDKSDDNLVVDVSNEDPSSPRASPAHSPRENGIDKNRLLKKDASSSPASTASSASSTSLKSKEMSLHEKASTPVLKSSTPTPRSDMPTPGTSATPGLRPGLGKPPAIDPLVNQAAAGLRTPLAVPGPYPAPFGMVPHAGMNGELTSPGAAYASLHNMSPQMS--AAAAAAAVVAYGRSPMVGFDPPPHMRVPTIPPNLAGIPGGKPAYSFHVTADGQMQPVPFPPDALIGPGIPRHARQINTLNHGEVVCAVTISNPTRHVYTGGKGCVKVWDISHPGNKSPVSQLDCLNRDNYIRSCKLLPDGCTLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMESSNVEVLHVNKPDKYQLHLHESCVLSLKFAYCGKWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISVDDKYIVTGSGDKKATVYEVIY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P16371-1", "uniprot_id": "GROU_DROME", "id": "P16371-1", "name": "Protein groucho", "aln": "MYPSPVRHPAAGGPPPQGPIKFTIADTLERIKEEFNFLQAQYHSIKLECEKLSNEKTEMQRHYVMYYEMSYGLNVEMHKQTEIAKRLNTLINQLLPFLQADHQQQVLQAVERAKQVTMQELNLIIGHQQQHGIQQLLQQIHAQQVPGGPPQPMGALNP-FGALGATMGLPHGPQGLLNKPPEHHRPDIKPTGLEGPAAAEERLRNSVSPAD--REKYRTRSPLDIENDSKRRKDEKLQ----EDEGEKSDQDLVVDVANEMES-------HSPRPNGEHVS-MEVRDRESLNGERLEKPSSSGIKQE---------RPPSRSGSSSSRS---TPSLKTKDMEKPGTPGAKARTPTPNAAAP-------APGVNPK--QMMPQG-------PPPAGYPGAPYQRPADP---YQRPPSDPAYGRPPPMPYDPHAHVRTNGIP-HPSALTGGKPAYSFHMNGEGSLQPVPFPPDALVGVGIPRHARQINTLSHGEVVCAVTISNPTKYVYTGGKGCVKVWDISQPGNKNPVSQLDCLQRDNYIRSVKLLPDGRTLIVGGEASNLSIWDLASPTPRIKAELTSAAPACYALAISPDSKVCFSCCSDGNIAVWDLHNEILVRQFQGHTDGASCIDISPDGSRLWTGGLDNTVRSWDLREGRQLQQHDFSSQIFSLGYCPTGDWLAVGMENSHVEVLHASKPDKYQLHLHESCVLSLRFAACGKWFVSTGKDNLLNAWRTPYGASIFQSKETSSVLSCDISTDDKYIVTGSGDKKATVYEVIY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:*. ***:. .. * *:****.::*:******:********:*******:.********************:**************: *::***. :***** *********** *** ***:** : * *.: *. ** .*:* * * : .**.: .* ...* .:. : * * . * . **: .* * . : *. ::..* *:** :. : :.:*:***::*****:** * **** ** . . : :* .. .. .. **:.:*.: * :*.:.:.** **. .:. :** . * * * **. .** * *:*:. .* *.*.. * . ..: ****.* : :** .*:*. ** : :.:.*********:..:*.:**********:* ************.**************::***************:****.********:******* ****** *********.*******:***********:********************************: ****************** **::**************************:************:*******.*:*****..*****************:** ******************************:*********.*********************", "identical_positions": 471, "similar_positions": 141, "identity": "60.62%" }, { "cls_id": "homologset.agr.RGD:1309238", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q6ZQ03-1", "uniprot_id": "FNBP4_MOUSE", "id": "Q6ZQ03-1", "name": "Formin-binding protein 4", "aln": "--------------------------MMGKKSRAVPGRRPILQLSPPGPRSSTPGRDPDPDPDPEADSTAAATSQSAPAAATAAAATSPAVPASAAPEDSPSEDEQEVVVEVPNVVQNPPTPVMTTRPTAVKATGGLCLLGAYADSDDDESDVSEKTAQSKEANGNQATDIDSTLANFLAEIDAITAPQPAAPVVASAPPPTPPRPEPKEAATPALSPTASNGSDTAQTPGWHYDTQCSLAGVEIEMGDWQEVWDENTGCYYYWNTQTNEVTWELPQYLATQVQGLQHYQPSSVTGTEAAFVVNTDMYTKERTTAASSSKSGPVITKREVKKEVNEGIQALSNSEEERKGVAAALLAPLLPEGVKEEEERWRRKVICKEADPVSETKETSTASEETGPSIKPPEVMMDGTEDPSQEELCSVVQSGESEEEEEEEEQDTLELELALERKKAELRALEEGDGSVSGSSPRSDISQPASQDGVRRIMSKRGKWKMFVRATSPESTSRSSSKTGRDSPENGETAIGAEDSEKIDEISDKETEVEESSEKIKVQLAPKVEEEQDLKFQIGELANTLTSKFEFLGINRQSISNFHMLLLQTETRIADWREGALNGNYLKRKLQDAAEQLKQYEINATPKGWSCHWDRDHRRYFYVNEQSGESQWEFPDGEEEEE-SQTKEVRDESLPKLTVKDKTCTDPNSTESSENPTGSLCKESFSGQVSSS-LMPLTPFWTLLQSNVPVLQPPLPLEMPPPPPPPPESPPPPPPPPPPPPPLEDGEIQEVEMEDEGSEEPPAPGTEEDTPLKPSTQTTAVTSQSLVDSTASSPPSNKAVKRKAPEMSTSVVQRSATIGSSPVLYSQSAIAAGHQAVGMAHQAVGMAHQAVSASHAAAAGVGHQARGMSLQSNYLGLAAAPALMSYAECSVPIGVTTPSLQPAQARGTMAAPAVVEPPPPPPPPPTPTPPPPPPAPKVPPPEKTRKGKKDKAKKSKTKMPSLVKKWQSIQRELDEEDNSSSSEEDRESTAQKRIEEWKQQQLVSGLAERNANFEALPEDWRARLKRRKMAPST", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1MAK1-1", "uniprot_id": "F1MAK1_RAT", "id": "F1MAK1-1", "name": "Formin-binding protein 4", "aln": "MNIDYAPGRRAPAPLICRRSLLALGLVMGKKSRAVPGRRPILQLSPPGPRSSTPGRDPDPDPDPETDSTAAATSQSVPAAATAAAATSPAVPATAAPEDSPSEDEQEVVVEVPNVVQNPPKPVMPTRPTTVKATGGLCLLGAYADSDDDENDISEKTAQSKESNGNQSTDIDSTLANFLAEIDAITAPQPVAPVVASAPPPTPPRPEPKEAATPALSSAASNGTDAAQTAGWHYDTQCSLAGVEIEMGDWQEVWDENTGCYYYWNTQTNEVTWELPQYLATQVQGLQHYQTSSVTGTEAAFVVNTDIYAKEKMIPASSNKSGPVIAKREVKKEVNEGIQALSNSEEERKGVAAALLAPLLPEGVKEEEERWRRKVICKEADPVSEAKETSTAAEETGPSIKPPEVAMDSTEDPSQEDLCSVVQSGESEEEEEEE-QDTLELELALERKKAELRALEEGDGSVSGSSPRSDISQPASQDGMPRIMSKRGKWKMFVRATSPESTSRSSSKTGRETPENGETAIGAEDSEKINENSDKEAEVEESSEKIKVQIAPKVEEEQDLKFQIGELANTLTSKFEFLGINRQSISNFHMLLLQTETRIADWREGALNGNYLKRKLQDAAEQLKQYEINATPKGWSCHWDRDHRRYFYVNEQSGESQWEFPDGEEEEE-SQAQEVRDESLPKLTEKDKTCTDSNSAESSENSTGSLCKESFSGQVSSS-LMPLTPFWTLLQSNVPVLQPPLPLEMPPPPPPPPESPPPPPPPPPPPPPLEDGEIQEVEMEDEGSEEPPAPGTEEDTPLKPSTQTTVVTSQSSVDSTASSPPSTKAVKRKAPEISTAVVQRSATIGSSPVLYSQSAIAAGHQAVGMAHQAVSVSH--------AAAGMGHPTRGMSLQSNYLGLAAAPAILSYAECSVPIGVTTPSLQPAQARGTVAAPAVVEPPPPPPPPPTSTPPPPPPAPKGPPPEKTRKGKREKAKKSKTKMPSLVKKWQSIQRELDEEDNSSSSEEDRESTAQKRIEEWKQQQLVSGLAERNANFEALPEDWRARLKRRKMAPNT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N3X1-1", "uniprot_id": "FNBP4_HUMAN", "id": "Q8N3X1-1", "name": "Formin-binding protein 4", "aln": "---------------------------MGKKSRAVPGRRPILQLSPPGPRGSTPGRDPEPEPDTEPDSTAAVPSQPAPSAATT---TTTAVTAAAASDDSPSEDEQEAVQEVPRVVQNPPKPVMTTRPTAVKATGGLCLLGAYADSDDDDNDVSEKLAQSKETNGNQSTDIDSTLANFLAEIDAITAPQPAAPVGASAPPPTPPRPEPKEAATSTLSSSTSNGTDSTQTSGWQYDTQCSLAGVGIEMGDWQEVWDENTGCYYYWNTQTNEVTWELPQYLATQVQGLQHYQPSSVPGAETSFVVNTDIYSKEKTISVSSSKSGPVIAKREVKKEVNEGIQALSNSEEEKKGVAASLLAPLLPEGIKEEEERWRRKVICKE-EPVSEVKETSTTVEEATTIVKPQEIMLDNIEDPSQEDLCSVVQSGESEEEEEQD---TLELELVLERKKAELRALEEGDGSVSGSSPRSDISQPASQDGMRRLMSKRGKWKMFVRATSPESTSRSSSKTGRDTPENGETAIGAENSEKIDENSDKEMEVEESPEKIKVQTTPKVEEEQDLKFQIGELANTLTSKFEFLGINRQSISNFHVLLLQTETRIADWREGALNGNYLKRKLQDAAEQLKQYEINATPKGWSCHWDRDHRRYFYVNEQSGESQWEFPDGEEEEEESQAQENRDETLAKQTLKDKTGTDSNSTESSETSTGSLCKESFSGQVSSSSLMPLTPFWTLLQSNVPVLQPPLPLEMPPPPPPPPESPPPPPPPPPP---AEDGEIQEVEMEDEGSEEPPAPGTEEDTPLKPSAQTTVVTSQSSVDSTISSSSSTKGIKRKATEISTAVVQRSATIGSSPVLYSQSAIATGHQAAGIGNQATGIGHQTIPVS-LPAAGMGHQARGMSLQSNYLGLAAAPAIMSYAECSVPIGVTAPSLQPVQARGAVPTATIIEPPPPPPPP----PPPPPPAPKMPPPEKTKKGRKDKAKKSKTKMPSLVKKWQSIQRELDEEDNSSSSEEDRESTAQKRIEEWKQQQLVSGMAERNANFEALPEDWRARLKRRKMAPNT", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***********************.*******:*:**.*.*****..**..*:***: *:.**.*:**.:*********.* ***.******.***.****:*******************:.*:*** *****:****:**********************.*** ******************.:**.::***:*::**.**:********** **********************************************.***.*:*::******:*:**: ..**.******:*********************:*****:*********:*************** :****.*****: **: . :** *: :*. ******:***************:: ******.***********************************: *:****************************::***********:****:* **** *****.****** :**************************************:****************************************************************************** **::* ***:*.* * **** **.**:****..**************** ********************************************** ********************************:***.***** **** **..*.*.:****.*:**:*********************:****.*:.:**..:.* .***:** :*****************::************:*****.****::.:.:::********* ********* ******:**:::*******************************************************:*************************.*", "identical_positions": 860, "similar_positions": 123, "identity": "81.21%" }, { "cls_id": "homologset.agr.RGD:1309240", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XHX8-1", "uniprot_id": "SMAP2_RAT", "id": "Q5XHX8-1", "name": "Sperm microtubule associated protein 2", "aln": "MGELGEHRSRSSLLSIPVLDTKTSGGSEYRESDGSLDLQSTLFEDHWLQSSQ----ATTERNTDDPEEEIPPEEMVGEELPEVSN-------LEDSLRRDLEVEVVGMSHLSINERTTPTTSSAKCRKKKNHRLLELAKPKFNWQCLKDRTGRCCKGHVWISPRKTNLQFCLYWPSVYWTERFIEDTTLTITVPEVSRRVEELSRPKRFYQEYYNNNRTTPIWPIPRSTLEYQASNRLKRLATPKIRNNIWSINMSEVSQVSRAAQMAVPTPRTLRLAKPRAPATLLEEWDPMPKPKPYVSDYN---RLLQLATPKALSEK---CVPDRSPQWEVLNVTKNAVASSRIISLAQPKIRKDLNEGYNPYYISPASLVA-QASPRIYELAVPKHITKKV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JMB1-1", "uniprot_id": "SPMA2_MOUSE", "id": "Q9JMB1-1", "name": "Sperm microtubule associated protein 2", "aln": "MGELGEHR--ASLLSNPIPEVKTLGELKQGQNNGNLDLESEPFGSHWLQGSK----ATTGRTSEEPEEEIPPEEMAGEELPETSN-------LDGPLQQDLEVEVVEMSHLSITER-TPSVSTAKGRKKRSRRLLELAKPKTNWQCLRDRTGRCCKGYAWISPRKTNLQFCLYWPSVYWTERFIEDTTLTITVPVVSQRMEELSRPKRFYQEYYNNNRTTPIWSIPRSTLEYQASNRLKQLATPKVRNNIWSINMSEVSQVSRAAQMAVPTPRTLRLAKPRPPATLLEEWDPMPKPKPYVSDYN---RLLQLATPKALSEK---CVPDRSPQWEVLDVTKNAVASSRIISLAQPKIRKDLNEGYNPYYISPASLVA-QASPRIYELATPKYITKKV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P2T0-1", "uniprot_id": "SPMA2_HUMAN", "id": "Q9P2T0-1", "name": "Sperm microtubule associated protein 2", "aln": "---MGDSR-RRSLGNQPSSE--AAGRSEREQDGDPRGLQSSVYESRRVTDPERQDLDNAELGPEDPEEELPPEEVAGEEFPETLDPKEALSELERVLDKDLEEDIPEISRLSISQKLPSTTMTKARKRRRRRRLMELAEPKINWQVLKDRKGRCGKGYAWISPCKMSLHFCLCWPSVYWTERFLEDTTLTITVPAVSRRVEELSRPKRFYLEYYNNNRTTPVWPIPRSSLEYRASSRLKELAAPKIRDNFWSMPMSEVSQVSRAAQMAVPSSRILQLSKPKAPATLLEEWDPVPKPKPHVSDHN---RLLHLARPKAQSDK---CVPDRDPRWEVLDVTKKVVASPRIISLAKPKVRKGLNEGYDRRPLASMSLPPPKASPEKCDQPRPGL-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VD59-1", "uniprot_id": "Q9VD59_DROME", "id": "Q9VD59-1", "name": "", "aln": "-MTIQGLKCDLSPTVTTCLQLKDCVRPDCCPIRDPIPYDAECFVR-------------------DIGQELDKLTRRHERMFVKRR-----RLMEMAIPRRRTCRFVPKCACSFPKS---IEMVRPCDAQNHTRTEQLALPTVRRLLHRRRTAILAG----DSIGESILNRWLRYSYLSLYSRLTNIQPLVKPKKKKKKTEKQLAKHEKYIEKLAKPKKAPKVPKPDRGAGEFDP-VRLNQLASPKA----YLEEIKPKWELTSQMKDYKATKRIKQISQPVVRDNVHINENPE-KVSPNALRYKPSARIKEMSEPLTTRDANQGLADVKENPFGIAPNALKYKASTRIKELAEPKEFENTHIRENPFAISPAALKA-KASPRLIELAKPKGG----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * . : . . :: : : :*: *.: :: : : . . *: : :. * :** *. . : *.. * : *: * :. : .*: : .*. . .: ::*:: ::: : : :::. : *.: *: . **:.**:** : :. ::: : .: * ::::* .: : :* * .* . :: *: .:: * : : . :. : : : : **.** .**:** :. : : ::. :* . :***. : . * ", "identical_positions": 43, "similar_positions": 114, "identity": "10.86%" }, { "cls_id": "homologset.agr.RGD:1309241", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CXU9-1", "uniprot_id": "EIF1B_MOUSE", "id": "Q9CXU9-1", "name": "Eukaryotic translation initiation factor 1b", "aln": "-----------------------------------------------------------------------------MSTIQNLQSF--DPFADATKG-DDLLPAGTEDYIHIRIQQRNGRKTLTTVQGIADDYDKKKLVKAFKKKFACNGTVIEHPEYGEVIQLQGDQRKNICQFLL-EVGIVKEEQLKVHGF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60739-1", "uniprot_id": "EIF1B_HUMAN", "id": "O60739-1", "name": "Eukaryotic translation initiation factor 1b", "aln": "-----------------------------------------------------------------------------MSTIQNLQSF--DPFADATKG-DDLLPAGTEDYIHIRIQQRNGRKTLTTVQGIADDYDKKKLVKAFKKKFACNGTVIEHPEYGEVIQLQGDQRKNICQFLL-EVGIVKEEQLKVHGF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0KVZ2-1", "uniprot_id": "A0ABK0KVZ2_RAT", "id": "A0ABK0KVZ2-1", "name": "", "aln": "EFGFRSVASAGWGAACPLGLRHVISCGGRAGLEQKARALSSSSTGLFPEGQQRAPPDFSDDICTDKKKNQERGINKWPTTTRNKNYFFVDPFADASKG-DDLLPAGTEDYIHIRIQQRNGRKTLTTVQGIADDYDKKKLVKAFKKKFACNGTVIEHPEYGEVIQLQGDQRKNICQFLI-EIGLAKDDQLKVHGF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VZS3-1", "uniprot_id": "ETIF1_DROME", "id": "Q9VZS3-1", "name": "Eukaryotic translation initiation factor eIF1", "aln": "------------------------------------------------------------------------------MSIQNLNTR--DPFADAIKGNDDDIQDG---LVHIRIQQRNGRKTLTTVQGLSAEYDLKKIVRSCKKEFACNGTVIEHPEYGEVLQLQGDQRENICQWLT-KVGLAKPDQLKVHGF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32911-1", "uniprot_id": "SUI1_YEAST", "id": "P32911-1", "name": "Eukaryotic translation initiation factor eIF-1", "aln": "------------------------------------------------------------------------------MSIENLKSF--DPFAD--TGDDETATSN---YIHIRIQQRNGRKTLTTVQGVPEEYDLKRILKVLKKDFACNGNIVKDPEMGEIIQLQGDQRAKVCEFMISQLGLQKKN-IKIHGF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .* : ***** .* *: . :******************:. :** *:::: **.*****.:::.** **::******* ::*::: ::*: * : :*:***", "identical_positions": 54, "similar_positions": 33, "identity": "27.84%" }, { "cls_id": "homologset.agr.RGD:1309242", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U2U7-1", "uniprot_id": "MCES_RAT", "id": "Q5U2U7-1", "name": "mRNA cap guanine-N(7) methyltransferase", "aln": "MESS-------------VKASVDSETESSPGVNETAAASGQRLSEKTR--QQADQPKTQ----DDLVEQNSSYVQDSPSKKRKLDVEIILDEKHSEDDGGASKRSKLERGGGSEDEPSPGGLTERKRKLQPQDALETQTRKFQKLEEGHSSAVAAHYNELQEVG-LVKRSQSRIFYLRNFNNWIKSILIGEILEKVR--QRKNRDITVLDLGCGKGGDLLKWRKGRISRLVCADIADISMKQCQQRYEDMKCR-RDNEYI--FSAEFITADCSKELLVEKFHDPEMYFDICSCQFACHYSFESLEQADMMLRNACGRLNPGGYFIGTTPNSFELIRRLEAS----ETESFGNEIYTVKFQKKGN-------YPLFGCKYDFNLEGVVD-VPEFLVYFPLLTEMAKKYNMKLIYKKTFLEFYEEKIKNNENKMLLKRMQALESYPANENSKLASEKAGDYAHAAEYMKNSQVRLPLGTLSKSEWEATSIYLVFAFEKQQ---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D0L8-1", "uniprot_id": "MCES_MOUSE", "id": "Q9D0L8-1", "name": "mRNA cap guanine-N(7) methyltransferase", "aln": "MEGS-------------AKASVASDPESPPGGNEPAAASGQRLPENTPPCQQVDQPKMQKEFGEDLVEQNSSYVQDSPSKKRKLDVEIILEEKHSEDDGGSAKRSKLERGDVSEDEPSLGRLNQTKRKLQPQD--DEVPQKLQKLEEGHSSAVAAHYNELQEVG-LAKRSQSRIFYLRNFNNWIKSILIGEILEKVR--QRKTRDITVLDLGCGKGGDLLKWRKGRISRLVCADIADISMKQCQQRYEDMRCR-RDNEHI--FSAEFITADCSKELLVEKFRDPEMYFDVCSCQFACHYSFESQVQADTMLRNACGRLNPGGYFIGTTPNSFELIRRLEAS----ETESFGNEIYTVKFQKKGN-------YPLFGCKYDFNLEGVVD-VPEFLVYFPLLTEMAKKYNMKLIYKKTFLEFYEEKIKNNENKMLLKRMQALEQYPAHENSKLASEKVGDYTHAAEYLKKSQVRLPLGTLSKSEWEATSIYLVFAFEKQQ---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43148-1", "uniprot_id": "MCES_HUMAN", "id": "O43148-1", "name": "mRNA cap guanine-N(7) methyltransferase", "aln": "MANSAKAEEYEKMSLEQAKASVNSETESSFNINENTTASGTGLSEKTSVCRQVDIARKRKEFEDDLVKESSSCGKDTPSKKRKLDPEIVPEEKDCGDAEGNSKKRKRETEDVPKDKSSTGDGTQNKRKIALED----VPEKQKNLEEGHSSTVAAHYNELQEVG-LEKRSQSRIFYLRNFNNWMKSVLIGEFLEKVR--QKKKRDITVLDLGCGKGGDLLKWKKGRINKLVCTDIADVSVKQCQQRYEDMKNR-RDSEYI--FSAEFITADSSKELLIDKFRDPQMCFDICSCQFVCHYSFESYEQADMMLRNACERLSPGGYFIGTTPNSFELIRRLEAS----ETESFGNEIYTVKFQKKGD-------YPLFGCKYDFNLEGVVD-VPEFLVYFPLLNEMAKKYNMKLVYKKTFLEFYEEKIKNNENKMLLKRMQALEPYPANESSKLVSEKVDDYEHAAKYMKNSQVRLPLGTLSKSEWEATSIYLVFAFEKQQ---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1MTD3-1", "uniprot_id": "MCES_DANRE", "id": "Q1MTD3-1", "name": "mRNA cap guanine-N(7) methyltransferase", "aln": "----------------------------------------------------------------MMAQNSRLFEMDSPYADAKVDKDSIGSSFDSSQTSTSSSSSSVKRRRDGDEE---DDDHSPSKKLVTED-------------SLHSQKVATHYNKIKECG-LAERNKSRIVYMRNFNNWLKSVLIAEILDKVR--QKR-REVTVLDLGCGKGGDLLKWKKGRIDKLVCADIAAVSIEQCQQRYNDVRRRGHPNDRT--FSAEFITADCSRELLSEKLQDPELQFDVCSCQFVYHYSFESESQADTMLRNACERLRPGGFFIGTTPDAYELVKRLEES----DSNSFGNEVFSVTFQKKGE-------YPLFGCQYDFSLEGVVN-VPEFLVYFPLFVEMAKKYNMRLVYKKTFKEFFEEKVKDGKNKDLMQWMQALEQYPPDERGQLSSSGPGEYDHAKRKAADPAVRRPLGTLSKSEWEATSIYLVYVFEKMS---------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VJQ4-1", "uniprot_id": "MCES_DROME", "id": "Q9VJQ4-1", "name": "mRNA cap guanine-N(7) methyltransferase", "aln": "---------------------------------------------------------MSLNYEQNAADEQFARAHKAVSLSDDEESEGQAETTSAPNQEPHVSKSPREYYDEPGGK---GNGSGADDQDEPET--------EAASGAANTHVVAHHYNELKEAG-RKDRQKSKIFFMRNFNNWIKSQLINEYMSQIKQNKRMGDALRVLDMCCGKGGDLLKWEKAAISHLICTDIAEVSVEQCQRRYQDILQRSEKSKFANKFTAEFFACDSTLVRLRERYKDPSLQLNLVSCQFAFHYCFESMAQADCMMRNAAECLKPGGFFIATMPDAYEIIRRLRAAG--PDARRFGNDVYSIEFDCETDP------LPLFGAKYQFHLEGVVD-CPEFLVHFPTLVKLGRKYGLQLLKRSTFADYYKENLHHG--RHLLQRMSGLESVQPQR-----CENDEEFAHVSNFQG-AQRSRSVGTLSKSEWEAATLYLVCAFKKCKNTWDTNGKPLFEFDD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32783-1", "uniprot_id": "MCES_YEAST", "id": "P32783-1", "name": "mRNA cap guanine-N(7) methyltransferase", "aln": "-------------------MSTKPEKPIWMSQEDYDRQYGSITGDESSTVSKKD-SKVTANAPGDGNGSLPVLQSSSILTSKVSDLPIEAESGFKIQKRRHERYDQEERLRKQRAQKLREEQLKRHEIEMTAN-----------RSINVDQIVREHYNERTIIANRAKRNLSPIIKLRNFNNAIKYMLIDKYTKPGD---------VVLELGCGKGGDLRKYGAAGISQFIGIDISNASIQEAHKRYRSMRNLDYQVVLI---TGDCFGESLG--VAVEPFPDCRFPCDIVSTQFCLHYAFETEEKARRALLNVAKSLKIGGHFFGTIPDSEFIRYKLNKFPKEVEKPSWGNSIYKVTFENNSYQKNDYEFTSPYGQMYTYWLEDAIDNVPEYVVPFETLRSLADEYGLELVSQMPFNKFFVQEIPKWIERFSPKMREGLQRSDGRYGVEGDEKEAASYFYTMFAFRKVKQYIEPESVKPN--------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .: . : . : : : * ***: . .*. * *. :***** :* ** : . **:: ******* *: . *.::: **: *:::.::**..: :.: : . : * : :: * ** **.**: :* : *.. * **.*:.* *:: : :*. : :**.::.: *: : . :* * : **..:: **::* * : .:. :*.:.*: : .* .:: ::: . : : ..*: . .: :. ::. . ", "identical_positions": 63, "similar_positions": 109, "identity": "12.28%" }, { "cls_id": "homologset.agr.RGD:1309243", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AYG8-1", "uniprot_id": "Q6AYG8_RAT", "id": "Q6AYG8-1", "name": "Calreticulin", "aln": "MVRARVSLWAICVLRVALATVYFQEEFLDGERWRNRWVQSTNDSQ-FGHFRVSSGKFYGHKEKDKGLQTTQNSRFYAISASFKPFSNKGKTLVIQYTVKHEQKIDCGGGYIKVFPSDLDQKNLNGKSQYYIMFGPDICGFDIKKVHVILYFKNQYHENKKSIRCKVDGFTHLYTLILRPDLSYEVKVDGQSIESGSIEYDWNLTSLKKM-EKTSLESRDWDEVE------GNKAQDWEK--HFLDAGPSKPSDWNSELDGDW----LQKPPYEDGLKAEGID----KDVWLHQKMRPAGYLTQYDLSEFENIGAIGLELWQVRSGTIFDNFLITDDEEYAEKFG---KATWGETKGPEKEMDAIQAK---EEVKKAREEDE-DLLMGKFHRHNH-FSRFHR--QGEL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D9Q6-1", "uniprot_id": "CALR3_MOUSE", "id": "Q9D9Q6-1", "name": "Calreticulin-3", "aln": "MVSARALLWAICVLRVALATVYFQEEFLDGERWRNRWVQSTNDSQ-FGHFRVSSGKFYGHKEKDKGLQTTQNSRFYAISASFKPFSNKGKTLVIQYTVKHEQKMDCGGGYIKVFPSDLDQKKMNGKSQYYIMFGPDICGFDIKKVHVILYFKNQYHENKKPIRCKVDGFTHLYTLILRPDLSYEVKVDGQSIESGSIEYDWNLTSLRKT-EKTSLDSRDWDQVE------GSKVQDWEK--HFLDAGASKPSDWNSELDGDW----LQKPPYEDGLKAEGID----KDVWLHQKMRPAGYLTQYDLSEFENIGAIGLELWQVRSGTIFDNFLITDDEEYAEKFG---KATWGETKGPEKEMDAIQAK---EEVKKAREEDEEDLLMGKFHRHNH-FSRFHR--QGEL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96L12-1", "uniprot_id": "CALR3_HUMAN", "id": "Q96L12-1", "name": "Calreticulin-3", "aln": "MARALVQLWAICMLRVALATVYFQEEFLDGEHWRNRWLQSTNDSR-FGHFRLSSGKFYGHKEKDKGLQTTQNGRFYAISARFKPFSNKGKTLVIQYTVKHEQKMDCGGGYIKVFPADIDQKNLNGKSQYYIMFGPDICGFDIKKVHVILHFKNKYHENKKLIRCKVDGFTHLYTLILRPDLSYDVKIDGQSIESGSIEYDWNLTSLKK--ETSPAESKDWEQTK------DNKAQDWEK--HFLDASTSKQSDWNGDLDGDWPAPMLQKPPYQDGLKPEGIH----KDVWLHRKMKNTDYLTQYDLSEFENIGAIGLELWQVRSGTIFDNFLITDDEEYADNFG---KATWGETKGPEREMDAIQAK---EEMKKAREEEEEELLSGKINRHEHYFNQFHR--RNEL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P29413-1", "uniprot_id": "CALR_DROME", "id": "P29413-1", "name": "Calreticulin", "aln": "MMWCKTVIVLLATVGFISAEVYLKENFDN-ENWEDTWIYSKHPGKEFGKFVLTPGTFYNDAEADKGIQTSQDARFYAASRKFDGFSNEDKPLVVQFSVKHEQNIDCGGGYVKLFDCSLDQTDMHGESPYEIMFGPDICGPGTKKVHVIFSYKGKNHLISKDIRCKDDVYTHFYTLIVRPDNTYEVLIDNEKVESGNLEDDWDFLAPKKIKDPTATKPEDWDDRATIPDPDDKKPEDWDKPEHIPDPDATKPEDWDDEMDGEWEPPMIDNPEFKGEWQPKQLDNPNYKGAWEHPEIANPEYVPDDKLYLRKEICTLGFDLWQVKSGTIFDNVLITDDVELAAKAAAEVKNTQAGEKKMKEAQDEVQRKKDEEEAKKASDKDDEDEDDDDEEKDDESKQDKDQSEHDEL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . . : :. : . * **::*:* : *.*.: *: *.: .: **:* ::.*.**.. * ***:**:*:.**** * *. ***:.*.**:*::*****::******:*:* ..:**..::*:* * ********* . ******: :*.: * .* **** * :**:****:*** :*:* :*.:.:***.:* **:: : :* : :. ...**:: ..* :**:* *: *...:* .**:.::**:* :::* ::. :.: :. *..* * :: . *:.: .* ::* ::*::****:*******.***** * * : . * * . * :. * :* * ** *** :::: : .. .:.:. . .: :.**", "identical_positions": 149, "similar_positions": 145, "identity": "36.61%" }, { "cls_id": "homologset.agr.RGD:1309244", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AWZ3-1", "uniprot_id": "A0A8I6AWZ3_RAT", "id": "A0A8I6AWZ3-1", "name": "Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1", "aln": "MTLQQAGPGERSIGLLREADPLRAVGIHPSAWACPPPRSPPPPRSRDPQAPLGARPAVSARRPPPARPAPARISILNRRPPAPRPTAAGATTRAARNLGRGGGSRTAELCRKRPWDALRPGALDNEAAGAAARRGLCAPRPHLLARRVPCLSAHPAPHGSALRVRTPAVGPRGTRTGGLQGRCSRSLSAGLAARGGRGRRSPPARALHLASSAPEARVPAAGGAGCSRASEGGEAAAAPGDMYLLDGSGEPASSPADTMSRGMPPRKTVYRISVTMVRKEQLAAPAPRPTRRPRPARSPEAPGRLEEEAEEAAAEDPEIGPRAWDFRAFRTRSTGQLELGRLRPCAHDTEPTDLMGSPTTEGPSSPDGEEARAAPLRRSLSFRHWSEPEVPRSPALSGGRRHSSSGSLAWMPDDDVEAD--VVPEPVAGVQPAAEKRNTLDVGEVLSKNDALSDLERWERSKSKNRTLDNSDLQRLERARAAA--------AGPGAASEHRLLRFFSGIFARRDGGPSPRSGA-----LRSRGYFSLRRAPADTHSSSAESIEGSPRRDAFVNSQEWTLSRSVPELKVGIVGNLASGKSALVHRYLTGTYVQEESPED-MDAGGRFKKEIVVDGQSYLLLIRDEGGPPEAQFAMWVDAVIFVFSLEDEISFQTVYHYYSRMANYRNTSEIPLVLVGTQDAISSTNPRVIDDVRARKLSNDLKRCTYYETCATYGLNVERVFQDVAQKIVATRK---------------KQQLSIGPCKSLPNS-------PSHSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTP--------STSQKELR----------IDVPPTANTPTPVRKQSKRRSNLFTSRKGSDPDKEKKGLESRADSIGSGRAIPIKQGMLLKRSGKSLNKEWKKKYVTLCDNGVLTYHPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRATSACAPISSPKTNGLAKDMSSLHISPNSGNVTSAS--GSQMASGISLVSFNSRPDGMHQRSYSVSSADQWSDATVIANSAISSDTGLGDSVCSSPSISSSTSPKLDPPPSPHANRKKHRRKKSTSNFKADGLTGTAE-------------------------EQEENLEFIIVSLTGQTWHFEATTYEERDAWVQAIESQILASLQSCESSKNKSRLTSQSEAMALQSIRNMRGNSHCVDCDTQNPNWASLNLGALMCIECSGIHRNLGTHLSRVRSLDLDDWPMELIKVMSSIGNELANSVWEEGSQGRTKPSLDSTREEKERWIRAKYEQKLFLAPLP-----CTEFSLGQQLLHATAEEDLRTVILLLAHGSRDEVNETCGEGDGRTALHLACRKGNVVLVQLLIWYGVDVMARDAHGNTALAYARQASSQE----------------------------------------CIDVLLQYGCPDERFVLMATPNLSRKNNSRNNSSGRAPSVI-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BXK8-1", "uniprot_id": "AGAP1_MOUSE", "id": "Q8BXK8-1", "name": "Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNYQQQLANSAAIRAEIQRFES--------VHPNIYSIYELLERVEEPVLQN------------------------------QIREHVIAIE-----DAFVNSQEWTLSRSVPELKVGIVGNLASGKSALVHRYLTGTYVQEESPE-----GGRFKKEIVVDGQSYLLLIRDEGGPPEAQFAMWVDAVIFVFSLEDEISFQTVYHYYSRMANYRNTSEIPLVLVGTQDAISSTNPRVIDDVRARKLSNDLKRCTYYETCATYGLNVERVFQDVAQKIVATRK---------------KQQLSIGPCKSLPNS-------PSHSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTP--------STSQKELR----------IDVPPTANTPTPVRKQSKRRSNLFTSRKGSDPDKEKKGLESRADSIGSGRAIPIKQGMLLKRSGKSLNKEWKKKYVTLCDNGVLTYHPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRATSACAPISSPKTNGLAKDMSSLHISPNSGNVTSAS--GSQMASGISLVSFNSRPDGMHQRSYSVSSADQWSDATVIANSAISSDTGLGDSVCSSPSISSSTSPKLDPPPSPHANRKKHRRKKSTSNFKADGLSGTAE-------------------------EQEENLEFIIVSLTGQTWHFEATTYEERDAWVQAIESQILASLQSCESSKNKSRLTSQSEAMALQSIRNMRGNSHCVDCDTQNPNWASLNLGALMCIECSGIHRNLGTHLSRVRSLDLDDWPMELIKVMSSIGNELANSVWEEGSQGRTKPSLDSTREEKERWIRAKYEQKLFLAPLP-----CTEFSLGQQLLRATAEEDLRTVILLLAHGSRDEVNETCGEGDGRTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTALAYARQASSQE----------------------------------------CIDVLLQYGCPDERFVLMATPNLSRKSNSRNNSSGRAPSVI-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UPQ3-1", "uniprot_id": "AGAP1_HUMAN", "id": "Q9UPQ3-1", "name": "Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNYQQQLANSAAIRAEIQRFES--------VHPNIYSIYELLERVEEPVLQN------------------------------QIREHVIAIE-----DAFVNSQEWTLSRSVPELKVGIVGNLASGKSALVHRYLTGTYVQEESPE-----GGRFKKEIVVDGQSYLLLIRDEGGPPEAQFAMWVDAVIFVFSLEDEISFQTVYHYYSRMANYRNTSEIPLVLVGTQDAISSANPRVIDDARARKLSNDLKRCTYYETCATYGLNVERVFQDVAQKIVATRK---------------KQQLSIGPCKSLPNS-------PSHSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTP--------STSQKELR----------IDVPPTANTPTPVRKQSKRRSNLFTSRKGSDPDKEKKGLESRADSIGSGRAIPIKQGMLLKRSGKSLNKEWKKKYVTLCDNGVLTYHPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRATSACAPISSPKTNGLSKDMSSLHISPNSGNVTSAS--GSQMASGISLVSFNSRPDGMHQRSYSVSSADQWSEATVIANSAISSDTGLGDSVCSSPSISSTTSPKLDPPPSPHANRKKHRRKKSTSNFKADGLSGTAE-------------------------EQEENFEFIIVSLTGQTWHFEATTYEERDAWVQAIESQILASLQSCESSKNKSRLTSQSEAMALQSIRNMRGNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLGTHLSRVRSLDLDDWPVELIKVMSSIGNELANSVWEESSQGRTKPSVDSTREEKERWIRAKYEQKLFLAPLP-----CTELSLGQHLLRATADEDLRTAILLLAHGSRDEVNETCGEGDGRTALHLACRKGNVVLAQLLIWYGVDVTARDAHGNTALAYARQASSQE----------------------------------------CIDVLLQYGCPDERFVLMATPNLSRRNNNRNNSSGRVPTII-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B0C5-1", "uniprot_id": "A0A8M3B0C5_DANRE", "id": "A0A8M3B0C5-1", "name": "Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1", "aln": "------------------------------------------------MYLLDGNYPERMERGTPQRKTVYRIS---------------LTLVKKENLQDGGGST------HRRLENPKVSAYRREGASEAQRS-----SQLEELKEVEDETDEFSAHSYMRNFRTFSTG---------------HLELGRLKLLKRAQHAHKERELNQTCILPENGQNKAIENGAPGEKRAEDVDES--DRLKRDAEHGKVCSTAAANGEKTGIRKKILKTSR--------STEEPVSTWPDEPCEEPKS-----------------------------VKTAKESCISSLLAKGNGKSPKPAPQTPPTKRHPS---------LLRRSFSFRHWTGGELIRIRALSKEKHHSSSGCIGRDGEGNQTQPGVVLQNMAFAETDSTEKRNTLDVGEVLNKTDSVTELGRRERMKGKNRTLDNSDLLRLSDKSLVDKEGFIRGMGSRSSGQERKLIRFFSGIFSKKDGTSTPLSSPSNRALRKNGLLGAQQRAEMGYSQSSSESVNGCPLDDAFVNSQEWTLSRSVPELKVGIVGNLASGKSALVHRYLTGTYVQEESPEADVDAGGRFKKEIVVDGQSYLLLIRDEGGPPEAQFALWVDAVIFVFSLEDEISFQTVYHYYSRMANYRNTAEVPLVLVGTQDAISAANPRVIDDTRARKLSNDLKRCTYYETCATYGLNVERVFQDVAQKVVAIRK---------------KQQLSIGPCKSLPNS-------PSHSSVCAAPVSAVHISQNSNGGGSLSDYSSSVPSTP--------STSQKELR----------IDVPQTANTPTPVRKQSKRRSNLFTSRKGSEPDREKKGMDGRADSIGSGRAIPIKQGMLLKRSGKSLNKEWKKKYVTLCDNGVLTYHPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRAISTCAAPS-PKTNGLTKDMSNMQLGQAPGSVTSSSS-ASQMASGISLVSFNSRPDGMHQRSYSVSSADQWSEATVIANSGISTDTGLGDSVCSSPSISSTTSPKMDPPPSPHANRKKHRRKKSTSNFKVDGFSGTAEAKHRAWKLNRVGSLRNIYNNSSNAEEQEDNFEFVIVSLTGQTWNFEATSYEERDAWVQAIESQILASLQSCESSKQKSRLSSQSEAIALQSVRNMRGNTRCVDCEAQNPDWASLNLGALICIECSGIHRNLGTHLSRVRSLDLDEWPLELIKVMSAIGNELANSVWEANAQGRLKPAPDASREERERWIRAKYEQKLFLASLT-----CTELSLGQQLLRATAEEDLRLVVILLAHGSRDEVNETCGEGDGRTALHLACRKGNVVITQLLVWYGVDIMARDAHSNTALAYARQANSQE----------------------------------------CMDVLLQYGCPDERYPLMATPNLSRRNNNRNNSCSSMNSAVI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9NGC3-1", "uniprot_id": "CEG1A_DROME", "id": "Q9NGC3-1", "name": "Centaurin-gamma-1A", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------MSNYHPHSHPHALS----------------------------------HPHPQQVHNQLQNPHQNQLPPP-------------------------QRHNHAAPTAAASASGAP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SSSASASASASILVAHPPQPLISNSLAIRQEIQRFES--------VHPSIYAIYELIDLLPMADAQIAQ----------------------------SIRDHVVCIE-----DSFVNSQEWTISRSVPDLRLGIVGSLNSGKSALVHRYLTGSYMQEESPE-----GGRFKKEVFIDGQSYLLLIRDEGGAPEMQFAGWVDAVIFVFSLENEGSFNTVYNYYTKMAHFRNGQEIPMILVGTQDAISERNPRVIDDTRARKLASDLKRCSYYETCATYGLNVERVFQDACQKILSQRLPLPPQVQPARPTTPQGNRLGLAPYQAPTNGQRGQQQLPLRMSADFAQAEQKLWSLQAASSSTINENNNITKYNPGAANSLQGDCSQVQLRDPRDLAPPPGKELPTPTSTPTTSRK-SRRRSNLFIPSSSKKADKEK---EPKSSELGSGRSIPIKQGYLYKRSSKSLNKEWKKKYVTLCDDGRLTYHPSLHDYMDDVHGKEIPLQYVTVKVPGQKPRGSKSIITNSALTSSLMANGQRAQNTLSDGIGCLTLAKDNQRKLSEKLSLLGAGSIAAGAGGEPLKSNSSQQTSGDEGIAMSNSNSQTFIAGEVANAGNKLEAQTPNVK---------KRHRRMKSSS-VKAN----EAD--------------------------DNDGYEFYIVSLDSKQWHFEAANSEERDEWVAAVEQEIFKSLQSIESSKTKQATSTDLAAMLAIRQR-VPGNGFCVDCGAPNPEWASLNLGVLMCIECSGVHRNLGSHISKVRSLGLDDWPSPHLSVMLAIGNSLANSVWESNTRQRVKPTSQASREDKERWVRSKYEAKEFLTPLGNGSSAHPSPSPGQQLIEAVIRADIKSIVSILANCPSEVTNANVSARDVRTPLLLACAIGNLAIAQLLIWNGANIKHTDHEGRTCLAYARAAQSLATAKSIKAAAAAQAGTTIPAPAPPTNGGIPAPQYNVEDTTALVELLEGLGCP-EAAPLTASGTLPRRRDTLGTPYEKSVSGVI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : ** * . . .*: . : . .:: *:********:*****:*::****.* *************:*:****** *******:.:**************.** *** ************:* **:***:**::**::** *:*::********* *******.*****:.*****:******************..**::: * ::*.:.* :: .*. * : *. * .. * : ...::.: .. . .* . ** :** ::* .:.***. ** *:****** . .....*:** : ::..:****:****** * ***.****************:* ***********::****** * .******::* : * : : ..: : :. :. * :* :. :::. :**:. .* . * .. . .*::* * ** * .::* :...*..: . .: :*::. *:*** **:* .*.: *: :::. ** **** .: *:***:. **** ** *:*.:*: **** **** *. ::: *: * : ** **** : **:*******.*:******:*****:*:*:****.**:** :.** :***.******* .:: * **: :::**::***:*:*** * **:.* .. * **:*:.*. *:: : :**: . : .* . . * **.* *** **:.:.***:* *.:: * ...*.***** *.* :::* *** * * *: .*.*: :. ... : : ", "identical_positions": 388, "similar_positions": 240, "identity": "26.23%" }, { "cls_id": "homologset.agr.RGD:1309245", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "F1LW30-1", "uniprot_id": "UNC5D_RAT", "id": "F1LW30-1", "name": "Netrin receptor UNC5D", "aln": "------------------------------------------------------------------------MG--TGAADRSRGARWWLPWLGLCFWAAGAEAARGADSGEVLPDSIP--SAPGTLPHFIEEPEDAYIIKSNPIALRCKARPAMQIFFKCNGEWVHQNEHVSEESLDESSGLKVREVFINVTRQQVEDFHGPEDYWCQCVAWSHLGTSKSRKASVRIAYLRKNFEQDPQGREVPIEGMIVLHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQARLSDSGNYTCMAANIVAKRRSLSATVVVYVNGGWSSWTEWSACNVRCGRG-WQKRSRTCTNPAPLNGGAFCEGMSVQKITCTALCPVDG-----------------SWEVWSEWSVCSPECEHLRIRECTAPPPRNGGKFCEGLSQESENCTDGLCILDKKPLHEIKPQRWSRRGIENASDIALYSGLGAAVVAVAVLVIGVTLYRRSHSDYGVDVIDSSALTGGFQTFNFKTVRQGNSLLLNP----AMHPDLTVSR-----TYSGPICLQDPLDKELMTESSLFNPLSDIKVKVQSSFMVSLGVSER----AEYHGKNHSGTFP----------HGNNRGFSTIHPRNKTPYIQNLSSLPTRTELRTTGVFGHLGGRLVMPNTGVSLLIPHGAIPEENSWEIYMSINQGEPSLQSDGSE--VLLSPEVTCGPPDMLVTTPFALTIPHCADVSSEHWNIHLKKRTQQG-----KWEEVMSVEDE--STSCYCLLDPFACHVLLDSFGTYALTGEPITDCAVKQLKVAVFGCMSCNS-LDYNLRVYCVDNTPCAFQEVVSDERHQGGQLLEEPKLLHFKGNTFSLQISVLDIPPFLWRIKPFTACQEVPFSRVWSSNRQPLHCAFSLERYTPTTTQLSCKICIR----QLKGHEQILQVQTSILESERETITFFAQEDSTFPAQTGPKAFKIPYSIRQRICATFDTPNAKGKDWQMLAQKNSINRNLSYFATQSSPSAVILNLWEARHQQDGDLDSLACALEEIGRTHTKLSNITEPQLDDTDFNYSRQNGL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K1S2-1", "uniprot_id": "UNC5D_MOUSE", "id": "Q8K1S2-1", "name": "Netrin receptor UNC5D", "aln": "------------------------------------------------------------------------MG--TGAADGSRGARRWLPWLGLFFWAAGAAAARGADGSEILPDSIP--SAPGTLPHFIEEPEDAYIIKSNPIALRCKARPAMQIFFKCNGEWVHQNEHVSEESLDESSGLKVREVFINVTRQQVEDFHGPEDYWCQCVAWSHLGTSKSRKASVRIAYLRKNFEQDPQGREVPIEGMIVLHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQARLSDSGNYTCMAANIVAKRRSLSATVVVYVNGGWSSWTEWSACNVRCGRG-WQKRSRTCTNPAPLNGGAFCEGMSVQKITCTALCPVDG-----------------SWEVWSEWSVCSPECEHLRIRECTAPPPRNGGKFCEGLSQESENCTDGLCILDKKPLHEIKPQRWSRRGIENASDIALYSGLGAAVVAVAVLVIGVTLYRRSHSDYGVDVIDSSALTGGFQTFNFKTVRQGNSLLLNP----AMQPDLTVSR-----TYSGPICLQDPLDKELMTESSLFNPLSDIKVKVQSSFMVSLGVSER----AEYHGKNHSGTFP----------HGNNRGFSTIHPRNKTPYIQNLSSLPTRTELRTTGVFGHLGGRLVMPNTGVSLLIPHGAIPEENSWEIYMSINQGEPSLQSDGSE--VLLSPEVTCGPPDMLVTTPFALTIPHCADVSSEHWNIHLKKRTQQG-----KWEEVMSVEDE--STSCYCLLDPFACHVLLDSFGTYALTGEPITDCAVKQLKVAVFGCMSCNS-LDYNLRVYCVDNTPCAFQEVISDERHQGGQLLEEPKLLHFKGNTFSLQVSVLDIPPFLWRIKPFTACQEVPFSRVWSSNRQPLHCAFSLERYTPTTTQLSCKICIR----QLKGHEQILQVQTSILESERETITFFAQEDSTFPAQTGPKAFKIPYSIRQRICATFDTPNAKGKDWQMLAQKNSINRNLSYFATQSSPSAVILNLWEARHQQDGDLDSLACALEEIGRTHTKLSNITEPQIDDADFNYSRQNGL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6UXZ4-1", "uniprot_id": "UNC5D_HUMAN", "id": "Q6UXZ4-1", "name": "Netrin receptor UNC5D", "aln": "------------------------------------------------------------------------MGRAAATAGGGGGARRWLPWLGLCFWAAGTAAARGTDNGEALPESIP--SAPGTLPHFIEEPDDAYIIKSNPIALRCKARPAMQIFFKCNGEWVHQNEHVSEETLDESSGLKVREVFINVTRQQVEDFHGPEDYWCQCVAWSHLGTSKSRKASVRIAYLRKNFEQDPQGREVPIEGMIVLHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQARLSDSGNYTCMAANIVAKRRSLSATVVVYVNGGWSSWTEWSACNVRCGRG-WQKRSRTCTNPAPLNGGAFCEGMSVQKITCTSLCPVDG-----------------SWEVWSEWSVCSPECEHLRIRECTAPPPRNGGKFCEGLSQESENCTDGLCILDKKPLHEIKPQ-----SIENASDIALYSGLGAAVVAVAVLVIGVTLYRRSQSDYGVDVIDSSALTGGFQTFNFKTVRQGNSLLLNS----AMQPDLTVSR-----TYSGPICLQDPLDKELMTESSLFNPLSDIKVKVQSSFMVSLGVSER----AEYHGKNHSRTFP----------HGNNHSFSTMHPRNKMPYIQNLSSLPTRTELRTTGVFGHLGGRLVMPNTGVSLLIPHGAIPEENSWEIYMSINQGEPSLQSDGSE--VLLSPEVTCGPPDMIVTTPFALTIPHCADVSSEHWNIHLKKRTQQG-----KWEEVMSVEDE--STSCYCLLDPFACHVLLDSFGTYALTGEPITDCAVKQLKVAVFGCMSCNS-LDYNLRVYCVDNTPCAFQEVVSDERHQGGQLLEEPKLLHFKGNTFSLQISVLDIPPFLWRIKPFTACQEVPFSRVWCSNRQPLHCAFSLERYTPTTTQLSCKICIR----QLKGHEQILQVQTSILESERETITFFAQEDSTFPAQTGPKAFKIPYSIRQRICATFDTPNAKGKDWQMLAQKNSINRNLSYFATQSSPSAVILNLWEARHQHDGDLDSLACALEEIGRTHTKLSNISESQLDEADFNYSRQNGL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q95TU8-1", "uniprot_id": "UNC5_DROME", "id": "Q95TU8-1", "name": "Netrin receptor unc-5", "aln": "MAVINKAGNVIALLLVKLQLILLFTLSVSGELPQLDYGSLSASLEEDAIDPLTAMAPFANSLVTEESAQHKNNAELLGNSSEDENVRPQQGSSSSGLGSSGAAGGSGILLEEFNSGKLSPGEASNTLPIFLIEPESVFVVKNRPAVLKCKASHSLQVIFKCSGSSQPP-PSTHETHVDPHTGVNMEEVTATIHRDLVDEFFGDGPFKCECHAWSSRGVVKSQAATVHIAYIRKSFNQSPTSLRLELGSRAELRCEPPGGFPEPKLTWHKNNAVITADSEPGITVSAGT-LIFRQVALQHMANYSCSAENIAGRRVSDSAVLIVYVNGGWSTWSPWRECKCAGKPSQGRKRSRTCNNPMPLNGGAQCPGPQIQKSADCAACPEDTQIVSPDGFDISSSKRMARWSAWSDWSICSAECIQVRRRKCLT---QGQTQISSEAEEAGDLLLGAPGVGMAALIAAAGVGAVGSPSEATGSSSDIIPGYGKSLCAGKDIQT--AECRGEQCQIGKDDFDWTLYLG-LAFITAVCFAFGTALICCARRGIRTNPHYNMARSVMDADYMPGVVEKKEMRMHIEASNMGYDYVNPGHRYLPGEHIMGMGIGCGGVTEHHYDVPNLSANYTNPIDHLSVDYLSETGESSTADTSNSTFDMNGKLSILNASKSSTYEMLGSAGGQLRLYGGELLLFVPEHAIGKHVKKHVSLLLLSDECSRVSCATESSILCSSVVHSAPRNYSFVKPVILKIPHCLVAP-EQWHVHIYHADSEHDELSVNWRRAVSVGEETINTPMFVQLEATHVFIMTEQLGHFTVVAEPRIQQPSIKMKLLAFSQHTPPSNANCSLRIYVVKDFPNSRDICANVEAKLGGSFLGESQVFAFTLNSRNLNIRVRSAD----VEAAAPYEHAIPYQHILSNN-SILHCEFSLRRQDQNSLCVDFGQGSEDDYYTFNIPAHSMSGSAEELASTTNTTISIDRQGNYVNESCVMDFVQLPHATKRLICGALDPPRADERDWRLLAKKLNTDRYIAYFATKASPTEQILNLWECRAN-SSPGSSSNSVSHTIMALLLTLKEMGRQDVLDIIVETIGPLWI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . :. . ..* . : ::*: .. * * . .:. .*..*** *: **:..:::*..* .*:*** ::*::***.*. . * :* :*:::.** .: *: *::*.* : *:* *** *. **: *:*:***:**.*:*.* . .: : . *:*.** *.* .:: * **: * ::.: .* . *. **:**. *.. .**:* * **..:* * **.::********:*: * *: . :******.** ****** * * .:** : : ** * *..**:**:**.** ::* *:* : :. ::.. .: .: .. : : . ..*. : .* * :: * : : * .:.: * * :* : * : :. . *.:*: . :*. .::* * : :. : .: :.. :: :. : : ...::.:*:. .*. * * .:. .:. ** .. *. ::. *: . :: * ::* **:* : . : *::*. ** :. . .: : : ..* * * .:* :* *. * ..* : ...*. *.**** .. *:*::*: : .: :*...:** :* .*. : *:. .:: :.:* :::..** : . ::*: .*. : * : .**:* *.: * : : . * : **.:* *.::: *. *: .*:: * . . . : :*:.:: ..* . *** ***.* .: :. . :: : :. .:. * * :* : ::.. . . . .::*:: :: **.::*.*.*. :**::**:* . :* ::****::**: ******.* : .. .* .. . * .*.:: . :: : .: :", "identical_positions": 234, "similar_positions": 363, "identity": "21.53%" }, { "cls_id": "homologset.agr.RGD:1309246", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q91ZT9-1", "uniprot_id": "ASB8_MOUSE", "id": "Q91ZT9-1", "name": "Ankyrin repeat and SOCS box protein 8", "aln": "MSSSMWYIMQSIQSKYSLSERLIRTIAAIRSFPHDNVEDLIRGGADVNCTHGTLKPLHCACMVSDADCVELLLEKGAEVNALDGYNRTALHYAAERDEACVEVLLEYGANPNALDGNRDTPLHWAAFKNNAECVRALLESGASVNALDYNNDTPLSWAAMKGNLESVSILLDYGAEVRVINLKGQTPISRLVALLVRGLGTEKEDSCFELLHRAVGQFELRKNGIMPREVTKDQQLCEKLTVLCSAPGTLKTLARYAVRRSLGLQYLPDAVKGLPLPVSLKDYLLLLE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LDV0-1", "uniprot_id": "A0ABK0LDV0_RAT", "id": "A0ABK0LDV0-1", "name": "Ankyrin repeat and SOCS box protein 8", "aln": "MSSSMWYIMQSIQSKYSLSERLIRTIAAIRSFPHDNVEDLIRGGADVNCTHGTLKPLHCACMVSDADCVELLLEKGAEVNALDGYNRTALHYAAEKDEACVEVLLEYGANPNALDGNRDTPLHWAAFKNNAECVRALLESGASVNALDYNNDTPLSWAAMKGNLESVSILLDYGAEVRVINLKGQTPISRLVALLVRGLGTEKEDSCFELLHRAVGQFELRKNGIMPREVTKDQQLCEKLTVLCSAPGTLKTLARYAVRRSLGLQYLPDAVKGLPLPASLKEYLLLLE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H765-1", "uniprot_id": "ASB8_HUMAN", "id": "Q9H765-1", "name": "Ankyrin repeat and SOCS box protein 8", "aln": "MSSSMWYIMQSIQSKYSLSERLIRTIAAIRSFPHDNVEDLIRGGADVNCTHGTLKPLHCACMVSDADCVELLLEKGAEVNALDGYNRTALHYAAEKDEACVEVLLEYGANPNALDGNRDTPLHWAAFKNNAECVRALLESGASVNALDYNNDTPLSWAAMKGNLESVSILLDYGAEVRVINLIGQTPISRLVALLVRGLGTEKEDSCFELLHRAVGHFELRKNGTMPREVARDPQLCEKLTVLCSAPGTLKTLARYAVRRSLGLQYLPDAVKGLPLPASLKEYLLLLE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***********************************************************************************************:************************************************************************************** *********************************:******* *****::* *******************************************.***:******", "identical_positions": 279, "similar_positions": 6, "identity": "96.88%" }, { "cls_id": "homologset.agr.RGD:1309247", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z8G7-1", "uniprot_id": "D3Z8G7_RAT", "id": "D3Z8G7-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAVRFQVADMEELTIWEQHTATLYKDPRRGFGIAVSGGHDRAG-----GPVVVSDVVPGGPAEGRLQTGDHIVMVNGVSVENVTSAFAIQILKTCTKTANITVKRPRRVQLPATKASPAS-GHQLSDQ-------EEADHGRGYEGDSSSGSGRSWGERSRRSRAGRRVRMGSHGRRSSCGGSEANGLDLVSGYKRLPKQDVLMRPLKSVLVKRRNSEEFGVKLGSQIFIKHITESG---LAARNRGLQEGDLILQINGVSS-ANLSLSDTRRLIEKSEGQLTLLVLRDSG--QFLVNIPPAVS----------DSDSSLMEDISDLTSEL-------------------------------------------------------SQAPP----------------------------------------------SHIPPPPLKSRRS---------------------------------------PEDSQTDSPVETPQPQRRERS-----------------VDSRAIAEP-----------ESPGESRYD-------------------------------------IYRVPSRQSLEDR---------------------------------------------------------------GYSPDTRVVRFPKGVSIGLRLAGGNDVGIFVSGVQAGSPADGQGIQEGDEILQVNDMPFRNLTREEAVQFLLGLPAGEDVELVIQSKQ-DIFRKMVQSRVGDSFYIRTHFELEPSPPYGLGFTRGDVFHVVDTLYRGSGSGHGHSSHGGLWLAARMGRDLREQERGVIPNQSRAEQLASLEAAQRAAGLGPGASTGSNPRAEFWRLRGLRRGAKKTMTQRSREDLSALTRQGHYPPYERVVLREASFKRPVVILGPVADIAMKRLTTEVPEQFEIAESVSR----TDSPSKIIKLDTVRVIAERDKHALLDVTPSAIERLNYVQYYPVVIFCAPESRSALKALREWLAPASRRSSRRLYAQAQKLQKHSGHLFTATIPLNGTSDSWYQEVKAVIQQQQARPIWTAEDQLNGSSED-LDLPGHGLAASSG-------DLSCDSRANSDYED-------TDGEGTYTDREGEP-QDFDEEAP-------PTALARSSEPVWVDDH----------------------------------------------------------------------------------QGLMGHGR--IAAAEVQADSHYTPDQRRQDS------------------------------------MRTYKHEALRKKFTRARDIES-SDE-------------------------EGYDWGPATDL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QXY1-1", "uniprot_id": "ZO3_MOUSE", "id": "Q9QXY1-1", "name": "Tight junction protein ZO-3", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEELTIWEQHTATLYKDPRRGFGIAVSGGHDRAS-----GSVVVSDVVPGSPAEGRLRTGDHIVMVNGVSVENVTSAFAIQILKTCTKTANVTVKRPRRVQLPATKASPAS-GHQLSDQ-------EEADHGRGYEGDSSSGSGRSWGERSRRSRAGRRGRVGSHGRRSSGGGSEANGLDLVSGYKRLPKQDVLMRPLKSVLVKRRNSEEFGVKLGSQIFIKHITESG---LAARNHGLQEGDLILQINGVSS-ANLSLSDTRRLIEKSEGELTLLVLRDSG--QFLVNIPPAVS----------DSDSSLMEDISDLTSEL-------------------------------------------------------SQAPP----------------------------------------------SHVPPPPLKGQRS---------------------------------------PEDSQTDSPVETPQPRRRERS-----------------VNSRAIAEP-----------ESPGESRYD-------------------------------------IYRVPSRQSLEDR---------------------------------------------------------------GYSPDTRVVSFPKGASIGLRLAGGNDVGIFVSGVQAGSPADGQGIQEGDEILQVNGMPFRNLTREEAVQFLLGLPPGEDMELVTQSKTGHSLRRWSQSRVGDSFYIRTHFELEPSPPYGLGFTRGDVFHVVDTLYPGSGPGHGHSSHGGLWLAARMGRDLREQERGVIPNQSRAEQLASLEAAQRAAGVGPGASVGSNPRAEFWRLRSLRRGTKKASTQRSREDLSALTRQGHYPPYERVVLREASFKRPVVILGPVADIAMKKLTTEMPEEFEIAESMSR----TDSPSKIIKLDTVRVIAERDKHALLDVTPSAIERLNYVQYYPIVIFCAPESRPALKALREWLAPASRRSSRRLYAQAQKLQKHSGHLFTATIPLHGTSDSWYQEVKAVIQQQQARPIWTAEDQLNSSSED-LDLTGHGLAASSG-------DLSCDSRTNSDYED-------TDGEGAYTDREGGP-QDVDEEVA-------PTALARSSEPVWVDDH----------------------------------------------------------------------------------QGLMGHGTTITDKWETQADSHYTQDQRRQDS------------------------------------MRTYKHEALRKKFTRARDVES-SDD-------------------------EGYDWGPATDL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95049-1", "uniprot_id": "ZO3_HUMAN", "id": "O95049-1", "name": "Tight junction protein ZO-3", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEELTIWEQHTATLSKDPRRGFGIAISGGRDRPG-----GSMVVSDVVPGGPAEGRLQTGDHIVMVNGVSMENATSAFAIQILKTCTKMANITVKRPRRIHLPATKASPSSPGRQDSDEDDGPQRVEEVDQGRGYDGDSSSGSGRSWDERSRRPRPGRRGRAGSHGRRSPGGGSEANGLALVSGFKRLPRQDVQMKPVKSVLVKRRDSEEFGVKLGSQIFIKHITDSG---LAARHRGLQEGDLILQINGVSS-QNLSLNDTRRLIEKSEGKLSLLVLRDRG--QFLVNIPPAVS----------DSDSSPLEDISDLASEL-------------------------------------------------------SQAPP----------------------------------------------SHIPPPPRHAQRS---------------------------------------PEASQTDSPVESPR-LRRESS-----------------VDSRTISEPD------EQRSELPRESSYD-------------------------------------IYRVPSSQSMEDR---------------------------------------------------------------GYSPDTRVVRFLKGKSIGLRLAGGNDVGIFVSGVQAGSPADGQGIQEGDQILQVNDVPFQNLTREEAVQFLLGLPPGEEMELVTQRKQ-DIFWKMVQSRVGDSFYIRTHFELEPSPPSGLGFTRGDVFHVLDTLHPGPGQSH---ARGGHWLAVRMGRDLREQERGIIPNQSRAEQLASLEAAQRAVGVGPGSSAGSNARAEFWRLRGLRRGAKKT-TQRSREDLSALTRQGRYPPYERVVLREASFKRPVVILGPVADIAMQKLTAEMPDQFEIAETVSR----TDSPSKIIKLDTVRVIAEKDKHALLDVTPSAIERLNYVQYYPIVVFFIPESRPALKALRQWLAPASRRSTRRLYAQAQKLRKHSSHLFTATIPLNGTSDTWYQELKAIIREQQTRPIWTAEDQLDGSLEDNLDLPHHGLADSSA-------DLSCDSRVNSDYETDGEGGAYTDGEG-YTDGEGGPYTDVDDEPP-------APALARSSEPVQADES----------------------------------------------------------------------------------QSPRDRGR-ISAHQGAQVDSRHPQGQWRQDS------------------------------------MRTYEREALKKKFMRVHDAES-SDE-------------------------DGYDWGPATDL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BHQ8-1", "uniprot_id": "A0A8M2BHQ8_DANRE", "id": "A0A8M2BHQ8-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEEMTIWEQHTVTLSKDSKVGFGFAVSGGLDKPNPANGDAAVVVSDVIPTGPAMGRLQTRDQIVMVNGVSMENVTSLYTIQNLRKCGKTANITVKRPRTIQIPASSRPTRSASQSNILD----------DKGPQYKGQRGPDTTR-----TRRARSVTPDRNG-------------HDLPITSGYKRLPNQDVQNKPIKTTLIKKKPTDEYGMKLGSQIFIKHMTPTG---LAAKEGSLQEGDLVLKINGMTT-ENLSLLETKHLVEKSRGNLTMLVLRDDR--KFLVSIPEVEDSPQNSSDERREDSSSELEEISDLDSDLPVTNRASRRKDRKSNRNRADPVSKKLESPPLRSTLTRPAQSMPPRRVPSESESDRSNSPPPRHDTLDHRNKVLSGYSTLPNPRASPITSSSTSRPRRAVSESDSDRSASPPPRRESPRPDNHSRYKVLPDLPPPGLKPSSLSMSQDFPRRMASPYRPPPRDASESESDESARPQRRQGTPA--SQESRNRYRAAPEVKAAAVMEPPKWAKPSTPVQRAPSESESDGSYNSPPKQPPSPVSKSSRIKGPEMQMPITSIRQDPPLRAAPARPPPEDSSDSERAQSPLRRSDSHNSDHSFPRANGTLRSNVSIPNHTALTSKAVEEPLYVLPPDAVPTPNLGYSSDQNHISFVKEGSVGLRLVGGNDVGIFVGGVQPNSPAQKQGITEGDQILEVNGMDFNHFTREEAAMYLMNIRGGERIDMRTQNKA-DIYKKILKSNLGDSFYIRTHYDHVADSSVGLSFTRGEVFRVVDTMHRG---------KLGTWLAVRMGNDLHELDKGTIPNQTRAETLANLEQAQRIS---AAERQASGPRAEFWKLRGLR-GAKKS-NRRTRDDLLQLTIQGKFPAYEKVLLKEANFKRPIVILGPLNDIANEKLARELPDEFEIAEMVPRS--GNDSSSSVIKLDTVRRIAEQDKHPLLDITPTAIERLNYIQYHPMVLFLDPHSRKDVKSMRQKYMPGSSKSSRRLYAQALKLRKNYSTLFSARIDLQPNTNMWYDVLKDKIRQQQSKPVWVSEVAMEGGAEEDLDAFNR--ANNSD-------YLSGAS----DYED-------TDGEA-FTDGEAYTDNEDLEEPLGGIAKHRSSALARSSEPASVLNHSPEPPYNL------------------------------HEEEEEPEYTLPPSEVPPILHVPEPRSPRLVAGIPEEQEDVPSQRSFTDSDFSNDDVVAPQTPSDAPPKFRAPDPKDVQSKTPPLSAIEERLQQARMAEQIEPERKPSPSFIVLAHHEAMQMRRTQIRGSDSDSDENDRD--------------EDEYDEAEDIEWGPATEL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4K6Y7-1", "uniprot_id": "A0A0B4K6Y7_DROME", "id": "A0A0B4K6Y7-1", "name": "", "aln": "MKPSTRRRSFKTKPPKSNVYNPLVRYRPTAYVRNGIIGGAEGPGSSGVYQIADRVYTTSKMFLRDGYMYPRQPGQTMDPRFPLELHEFPQQFGATGLQLVSAPKVHIAGEYLASEQQQQQQQQQQQHQQVQEQQQLGRRKAAAAAEINLANQVYWLGKQKTRSRSRSNSVGNRSITSCMGGGGGGGEKERERGGDRDRPYIRNVDDLLQALGKRDGGDNNSNLLETASTHSSSQRRRFKKGDRTTWEYHTVAVTRVPGYGFGIAVSGGRDNPHFANGDPSIAVSDVLKGGPAEDRLQVNDRIISVNGVSLENVEYATAVQVLRDSGNTVQLVVKR-RVPLNPINAAGAVQHQHSHSLS------------SVGLMANGSGGVAPTPITSLSQPNSLN---------------------------SSLVQNASSGQPIKVTLTKGGKKDDYGVVLGCRLFVKEISSKAREQLNANGYSLQEGDIITRIHNTNCGDTMSLKEAKKIIDGCKERLNLVVLRDITNQTAVSQLNLNNSASHQASGNIYATHQPQVSGCSSSNNNLEDPYLPG----------------------------------------------GASYSSQ---------------------------------------------NLYVQPPTRTSNGPNIN------------------------------------GNGLNDEKSNLTPRGRSRGPIMDGVSLQQLDRPVTPTRGRSAAIDEPPR---PPPPRGSSGGAAQED--------------------------------------FYSSRRQLYEER----------------------------------------------------------------QSAEPRFISFQKEGSVGIRLTGGNEAGIFVTAVQPGSPASLQGLMPGDKILKVNDMDMNGVTREEAVLFLLSLQ--DRIDLIVQYCK-EEYDEVVTNQRGDSFHIKTHFHCDNPSKGEMAFKAGDVFRVIDTLHNG---------VVGSWQVLKIGRGHQEMQRGVIPNKSRAEELATAQFNATKKEMNANESRGN-----FFRRRRSTHRRSKSLSRENWDDVVFSDSISKFPAYERVVLRHPGFVRPVVLFGPVSDLARERLAKDFPDKFSTPLQDDDKSAATSGKCRIVRLSNIRDVMDRGKHALLDITPNAVDRLNYAQFYPVVIFLKTDSKHVIKQLRHGLPKAAHKSSKKLLEQCQKLERVWSHIFSTQIALS-DEESWYRKLRDSIDLQQSGAVWMSESKPVESLSDDFLFPMTTSRLSYASSPESDLELSPGPSASLSLGNLPQLVKASSDPSIATNQDNLDRDRDIIGEGLPPPYTVPYDHAVPANPNRRQTMDSSKYSIYGTNVPPQQQQPGVGGDTAAVRPQSLYGINAPDLPPRIDRQSKPGDIPLNTSGSSSRNGTLGRSAQERLFGKAVVQDDVQAEYITRNALVGSGAAETLDRQQQQQQQTHASLERQARLNAQLKANGVGAGGGGASTYDSVSSYDSYNNTQMAMQNLGRLGPNAPDDLKSVPNANGRPLPPTGQSHEYGRTPHDHRSFGGPNDLNRQSSPGRPHYHDMNASRNIDPRNGTPQRPSNLGLESSPRKPLVETKTDYGKYSRNNSVTQADYTKLPKTAPHGVVPPPNVSNGQGQMNGSGTPSSNGSGPFKPVPPPKPKNYRPPVQSGGSSGSGGTTPWENGDSGSPRSPNGFYYPPTPSHHHYGQQATPGSPSNGHMQPPPPQQQQPTYGGSNGNYGQAPPPQSYPQANGYNGNGHHYNGGSGTGPYIAPHRGMPPPIGNLPPHTPERHALDLAGSREQRGSAFELYRKPQIGATAGHHHNMSEMEPYDERYDDYYNMPPPAAHPSQGHHMQRSRSAPRYPHERPPHAQDPNYYGHYGTSRGHSQPRQQYSQHHQQQYYDDHGLEMGPPPLPPHKKKKSVLKSPLVALKNALLKSTRPLRRMNSMVEPERKPKGLRRQQSMLERGVQRPYYPDEYPTYPAGFEERAHGGQGMMQPHSQDAYYQRGGHYAPQQQEMMNSTYQNLEGEDIYGNIGNTVPRMPHHQDNGYGYDQYDLYANRACIDLERRQAEAAAASGGRNGRRIVRRHSTTTADRGGNPGPPRRPMISPGYEQDPQEIYQTRNGAYMLPDQRRAPSSEVMTRRRFYPGAANEQTEEEPLYQSRREMQREMQRNHLYQSKREMQERISQGKRDMEREFSPQSSSSQSEASNSEAIYQSRREAKESALKTRSQLRDQIYQTRREALDSMAEPIYVSKRGMGRPAPIYETREESILQSRENETDEKKEKECKTEQIQVEINAQPEEQIEDSTLSRSDLQKSSDTVIENPARAPLVQDEVDDDEEEEVQDQRDPAESSADQTEQPTAIENNLHNEGMVEQSQNDSDDVFEAADKVSPLAPPPAPVQPPTPRSGRAPFHISNILKRTAPPPSSPIGDSCTSIETQYTSQASLPVGPPNATSTPFSSSMSLPIAGPVNNQPSANGRFPTLPREPSTSRGFFDSNGGTLADKLWHVSLQIPPGAIPAGVRQEIYFTVSDPRMGQAVGGPPLDMENGETMLSPLVMCGPQGLEFLVPVTLNIPHCAGRTASLGLALKATDSEKNLHTEWDNIDLPSNAAAHTVSVKVDHF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * ** **.:: : . ***:*:*** *.. .:.****: .** .**:. *:*: *****:**. ::* *: . : .::.*** * * . . . :. . . .: . . :... . * .: :*:* .* * .:::*: **.::*:*.:: .. * *. .*****:: :*:. . .:** ::::::: .. .*.::**** : .: . .. :. *. .:* * :. ** . . . . ... :.: * : :: ** : * . *: *.: . : * * *:*:**.***:.**** .**..***. **: **:**:**.: :. .*****. :*:.: : ::: * . . .. ****:*:**:. . :.*. *:**:*:**:: * * * . ::*.. :* ::* ***::*** **. : . .. *:: * .*: .:.. :*: .::*.**:*:*:...* **:*::**: *:* ::*: :.*::*. . ... . :::*..:* : ::.**.***:**.*::**** *::*:*:* ..*: :* :*. .: :*:::* *. **.: . :*:: * * : ** :: * **: .:* :* . .: : . ** . . :.. . *: : . * .::* :. . : : .. : : . :: .* : .:* ..:* ", "identical_positions": 198, "similar_positions": 299, "identity": "7.37%" }, { "cls_id": "homologset.agr.RGD:1309249", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XJW2-1", "uniprot_id": "G45IP_RAT", "id": "Q5XJW2-1", "name": "Large ribosomal subunit protein mL64", "aln": "---------------------------------------------------------------------MAAPATRSRYLLRLTVTLG--------PRSRSYHAPPPPRRRPAPHWPDRENLMTPRWQLTPRYAAKQFGRHGAISGVPPASLWPSSEQLCELEAEEREWYPSLATMQESLRVQQQAAEARRQAREQHIAECMAKMPQMIENWRKQKRERWEKIQADKERRARLQAEAQEQLGYHVDPRSARFQELLQDLDKQQRKRLKEERQRQKKEARIAAMASAEGQDSAEAQDSAASGKPSS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CR59-1", "uniprot_id": "G45IP_MOUSE", "id": "Q9CR59-1", "name": "Large ribosomal subunit protein mL64", "aln": "---------------------------------------------------------------------MAALAMRSGYLLRLSVALG--------PRSRSYRAPPPPRRRPGPHSPDPENLLTPRWQLTPRYVAKQFGRHGAISGVPPASLWPTPEQLRELEAEEQEWYPSLATMQESLRLQQQALEARRQAREQRIAECMAKMPQMIENWRKQKRERWEKIQADKERRARLQAEAQERLGYHVDPRSARFQELLQDLDKQQRKRLKEERQRQKKEARIAAMASA------EAQDSAVSGEPSS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TAE8-1", "uniprot_id": "G45IP_HUMAN", "id": "Q8TAE8-1", "name": "Large ribosomal subunit protein mL64", "aln": "---------------------------------------------------------------------MAASVRQARSLLGVAATLA--------PGSRGYRARPPPRRRPGPRWPDPEDLLTPRWQLGPRYAAKQFARYGAASGVVPGSLWPSPEQLRELEAEEREWYPSLATMQESLRVKQLAEEQKRREREQHIAECMAKMPQMIVNWQQQQRENWEKAQADKERRARLQAEAQELLGYQVDPRSARFQELLQDLEKKERKRLKEEKQKRKKEARAAALAAA------VAQDPAASGAPSS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58J1F7-1", "uniprot_id": "A0AC58J1F7_DANRE", "id": "A0AC58J1F7-1", "name": "Large ribosomal subunit protein mL64", "aln": "MRCCVLPDGHMTFTCFKCTESIFSLQRIHCKHLNEVFPKWHTSYAPAEGVMTSALRAYMTLEVTGVSSNMAASLLSRRTASSFSFTKLNSLLPAAVIQIANYNPRPLRLNLKDPYIPDKESERTPEWQKTEKFERRLFGRYGRASGVNPVKLWPSAARLEELMAEEREWHPPVEQMLQNIAERQMEKEKRRIEREKTIAESMAKMPKLIADWKKQKREAKQKANEEKQKQVRLLAMARERFGFAVDPRSVKFKEMVAEIEKEEKKQRKLLKRQKKEEEQTSITPTA---------DSSQ------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VP13-1", "uniprot_id": "Q9VP13_DROME", "id": "Q9VP13-1", "name": "Large ribosomal subunit protein mL64", "aln": "----------------------------------------------MNVGKISVVTRLPALRSCAQYSSAAKAELPASLVGDVDVEPTYP------QTVDRSGLQPQHKNVLLNKLPYQEP--HSWIHLTEKYQRQAFGRYGAQSNVNPKICFDSHG---EKDSRQVMQLETLLKMLEKNRAQKAEELARINAREEDIAKKMEKLTQWKADLHAKIAKREADAAAAIQRKERLVEEVRRHFGFKVDTRDERFKEMLEQKEKEDKKKQKEAKRKAKEEKMMAKLVEK----------ASV------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . * . * * . : :: : *.*:* *.* * : : * :.: .: * :. :: : **: **: * *:.: : : : : . ::: ** .:. :*: **.*. :*:*:: : :*:::*: * ::: *:* : .: ", "identical_positions": 31, "similar_positions": 59, "identity": "10.16%" }, { "cls_id": "homologset.agr.RGD:1309250", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8J8YBF1-1", "uniprot_id": "A0A8J8YBF1_RAT", "id": "A0A8J8YBF1-1", "name": "Zinc transporter 6", "aln": "---------------------------MGTIHLFRKPQRSFFGKLLQEFRLVAADRRSWKILLFGAINVLCTGFLLMWCSSTNSIALTAYTYLTIFDLFSLFFFSLITCLISYWVMMRRPSAAYSFGFERLEVLAVFASTVLAQLGALFILKESAERFLEQPEIHTGRLLVGTFVALSFNLFTMLSIRNKPFAYVSEAASTSWLQEHVADLSRSLCGIIPGLSSIFLPRMNPFVLIDLAGALALCITYMLIEINNYFAVDTASAIAIALMTFGTMYPMSVYSGKVLLQTTPPHVIGQLDKLIREVSTLDGVLEVRNEHFWTLGFGSLAGSVHVRIRRDANEQMVLAHVTNRLCTLVSTLTVQIFKDDWIRPALSSGPVAPNVLNFSDHH----IIPMPLLKNN-DERTPVTSTPAKPSSPPPEFAFNTPGKNVSPVILLNTQTRPYGLGLNRGHTPYSSMFSQGLAFPGVGAGQGLRPTFPHIPSRYGIN-RMGQPRP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BJM5-1", "uniprot_id": "ZNT6_MOUSE", "id": "Q8BJM5-1", "name": "Zinc transporter 6", "aln": "---------------------------MGTIHLFRKPQRSFFGKLLQEFRLVAADRRSWKILLFGAINVLCTGFLLMWCSSTNSIALTAYTYLTIFDLF-----SLITCLISYWVMMRKPSPVYSFGFERLEVLAVFASTVLAQLGALFILKESAERFLEQPEIHTGRLLVGTFVALSFNLFTMLSIRNKPFAYVSEAASTSWLQEHVADLSRSLCGLIPGLSSIFLPRMNPFVLIDLAGAFALCITYMLIEINNYFAVDTASAIAIALMTFGTMYPMSVYSGKVLLQTTPPHVIGQLDKLIREVSTLDGVLEVRNEHFWTLGFGSLAGSVHVRIRRDANEQMVLAHVSNRLCTLVSTLTVQIFKDDWIRPALSSGPVAPNVLNFSDHH----VIPMPLLKNV-DERTPVTSTPAKPSSPPPEFSFNTPGKNVSPVILLNTQTRPYSLGLNRGHTPYSSVFSQGLAFPGVGAGQGLRPTFPHIPSRYGIN-RMGQPRP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6NXT4-1", "uniprot_id": "ZNT6_HUMAN", "id": "Q6NXT4-1", "name": "Zinc transporter 6", "aln": "---------------------------MGTIHLFRKPQRSFFGKLLREFRLVAADRRSWKILLFGVINLICTGFLLMWCSSTNSIALTAYTYLTIFDLF-----SLMTCLISYWVTLRKPSPVYSFGFERLEVLAVFASTVLAQLGALFILKESAERFLEQPEIHTGRLLVGTFVALCFNLFTMLSIRNKPFAYVSEAASTSWLQEHVADLSRSLCGIIPGLSSIFLPRMNPFVLIDLAGAFALCITYMLIEINNYFAVDTASAIAIALMTFGTMYPMSVYSGKVLLQTTPPHVIGQLDKLIREVSTLDGVLEVRNEHFWTLGFGSLAGSVHVRIRRDANEQMVLAHVTNRLYTLVSTLTVQIFKDDWIRPALLSGPVAANVLNFSDHH----VIPMPLLKGT-DDLNPVTSTPAKPSSPPPEFSFNTPGKNVNPVILLNTQTRPYGFGLNHGHTPYSSMLNQGLGVPGIGATQGLRTGFTNIPSRYGTNNRIGQPRP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6P0D1-1", "uniprot_id": "ZNT6_DANRE", "id": "Q6P0D1-1", "name": "Zinc transporter 6", "aln": "MVALDVLGITDSDAPVYRQKQEADTLVLGTIHPFRKAHRSVLGKLAQEFRLVTSDRRSWKILLFGVLNVVCTGCLLMWCSSTNSMALTAYTYLTIFDLF-----SLITCLLSLWVTMKKPSQIYSFGFQRFEVLAVFSSTVLVQLGSLFILKESVERFVEQPEVHTGRLLVGTFVALFFNLLTLLSVKNKPFVFVSEAASTSWLQEHVADLSRSLCGLIPALSSFLLPRMNPFVLINLAGAFALGITYMLIEINNYNAMDTASAVAIALMTFGTMYPMSVYSGKVLLQTTPSHVIGQLDKLLREVSTLDGVLEVRNEHFWTIGFGSLAGSVHVRIRRDADEQMVLAHVWNRLSALVSALTVHVFKDEWSRASLSSGVLPSAPLSLSEYVTAAAVFPAAPSRAQGSEPTPATSTPAKPSSPPPEFSFHTPGRHVQPVVFQTAHPHRPLYGGLQGPG-----VRLGLGPRGP-TLQAYR-TLSAAPHTYTSGTYTGPPRP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :**** ***.:**.:*** :*****::***********.:*::*** **********:************** **:***:* ** :::** *****:*:******:****.***:*******.***:****:************* ***:*:**::****.:***********************:**.***::**********:****:** *********** *:*****:**************************.*********:*******************:*****************:******** *** :***:***::***:* *.:* ** :.. *.:*:: ::* . : .: .*.**************:*:***::*.**:: .::.: * :* . **. * : *. * :. * * . * ***", "identical_positions": 317, "similar_positions": 86, "identity": "63.65%" }, { "cls_id": "homologset.agr.RGD:1309252", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XIN3-1", "uniprot_id": "MIPT3_RAT", "id": "Q5XIN3-1", "name": "TRAF3-interacting protein 1", "aln": "----MNAAVVRRTQEALGKVIRRPPLTEKLLNKPPFRYLHDIITEVIRITGFMKGLYTDAEMKSDNVKDKDAKISFLQKAIDVVMMVSGEPLAAKPARIVAGHEPERTNELLQLIGKCCLSKLSSDEAVKRVLAGEKGDSRGRVLRTSKAQEPDNKSVKEEESRTQK--EEKRSSEVKERSSSAEHKQKEELKEDSKPREKERDKEKAKEADRDRHREPDRDRNRDGEREKARARAKQDRDRNNKDRDRETERDRDRDRRSDGGKEKERQKDRDRD----KGKDRERRKSKNGEHTRDPDREKSRDADKSEKKAD------------------------ISVGASKSSTLKASKRRSKNSLEGRKEDNISAKILDSIVSGLNDEPDQETTAPEI-------------DDNSASLWRENAEPEPAVKQKGDSPSDAEGEAVPTSQDKLEVTENAEVSN---ELPSSLRRIP--RPGSARPAPPRVKRQES-TETLAGDRSGSGKTVSTVIID----SQNSDNEDDEQFVVEAAPQLSEIAEIEMVPSGDLEDEEKHGGLVKKILETKKDYEKLQQSPKPGEKERSLIFESAWKKEKDIVSKEIEKLRVSIQTLCKSALPLGKIMDYIQEDVDAMQNELQLWHSENRQHAEALSKEQSITDSAVEPLKAELSELEQQIKDQQDKICAVKANILKNEEKIQKMVHSINLSSRR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q149C2-1", "uniprot_id": "MIPT3_MOUSE", "id": "Q149C2-1", "name": "TRAF3-interacting protein 1", "aln": "----MNAAVVRRTQEALGKVIRRPPLTEKLLNKPPFRYLHDIITEVIRITGFMKGLYTDAEMKSENVKDKDAKISFLQKAIDVVMMVSGEPLAAKPARIVAGHEPERTNELLQLIGKCCLSKLSSDEAVKRVLAGDKGDSRGRAQRTSKAQEPNNKSGKEEESRIHK--EDKRSSEAKERSASAEHKQKEELKEDSKPREKERDKEKAKEADRDRHRDPDRDRNRDGEREKARARAK-DRDRNNRDRDREAERDRERDRRSEGGKEKERVKDRDRDRD--KGRDRERRKSKNGEHTRDPDREKSRDADKPEKKS--------------------------------SSSGEISRKLSDGSFK-----DVKAEMEADISVGAS---------------------------RSSTLKPSKRRSKHSLE--GDSPSDAEVEAGPAGQDKPEVMENAEVPS---ELPSSLRRIP--RPGSARPAPPRVKRQES-TETLVVDRSGSGKTVSSVIID----SQNSDNEDDEQFVVEAAPQLSEIADIDMVPSGELEDEEKHGGLVKKILETKKDYEKLQQSLKPGEKERSLIFESAWKKEKDIVSKEIEKLRVSIQTLCKSALPLGKIMDYIQEDVDAMQNELQLWHSENRQHAEALSQEQSITDSAVEPLKAELSELEQQIRDQQDKICAVKANILKNEEKIQKMVHSINLSSRR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TDR0-1", "uniprot_id": "MIPT3_HUMAN", "id": "Q8TDR0-1", "name": "TRAF3-interacting protein 1", "aln": "----MNAAVVRRTQEALGKVIRRPPLTEKLLSKPPFRYLHDIITEVIRMTGFMKGLYTDAEMKSDNVKDKDAKISFLQKAIDVVVMVSGEPLLAKPARIVAGHEPERTNELLQIIGKCCLNKLSSDDAVRRVLAGEKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERER----AKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGRKEDNISAKSLDSIVSGINNEPNQETTTSEIGTKEANINSTSISDDNSASLRCENIQPNPTEKQKGDSTSDAEGDAGPAGQDKSEVPETPEIPN---ELSSNIRRIP--RPGSARPAPPRVKRQDS-MEALQMDRSGSGKTVSNVITE----SHNSDNEEDDQFVVEAAPQLSEMSEIEMVTAVELEEEEKHGGLVKKILETKKDYEKLQQSPKPGEKERS-LFESAWKKEKDIVSKEIEKLRTSIQTLCKSALPLGKIMDYIQEDVDAMQNELQMWHSENRQHAEALQQEQRITDCAVEPLKAELAELEQLIKDQQDKICAVKANILKNEEKIQKMVYSINLTSRR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PGZ3-1", "uniprot_id": "MIPT3_DANRE", "id": "Q6PGZ3-1", "name": "TRAF3-interacting protein 1", "aln": "----MNESVAKKTQETLGKVIKKPPLTEKLLSKPPFRYLHDIFSEVIRTTGFMKGLYVEAEMKSDNVKDKDSKIAFLQKAIDVVMLVSGEPLAAKPARIVAGHEPEKTNELLQVIAKCCLNKLSSDEAVKRVLAGDKLDQKGKPS-TSRSQDKENREGRE----HHRDREERKG--IKESSGSREQKDPDQPKDQESKRDDKDRRRDAERSDKGRERERTKDRDRDKDKSRDREKDKTREKEREREKDRNREKERERDKDRDKKKERESHKDRERD----KDREREKRREKEKDKER-PRETEEKLKDRGDRKIK--------------------------------AAEEISKSKPQPEVASR---THQAETEEAESPSRIP--------------------------RPSSAKGQRRKPKTGGQGTEQDETESEGEAEGPSAEKPIPLENGDVTDPAALQTTHSRRLP--RPSSARPAAPRVKRQESYTDATPAERLGSGKTPASVILDGKKLSEDEDDEDGQFVVEEAAPPPSDVPEVESN-SLELQGDDKHGGLVKKILETKKDYESSPSS-KSKEQDRSLVSEASRKKERELVAREIERLRSSIQTVCRSALPLGKIMDYIQEDMDSMQNELQSWRKENKENAQALLQEQRITDGVVEPLKVELAELEQLIKDQQDKICAVKSNILKNEEKIQKMVSSISFSSQT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VFL0-1", "uniprot_id": "Q9VFL0_DROME", "id": "Q9VFL0-1", "name": "TRAF3-interacting protein 1", "aln": "MSEKDLDAIILETQKVLGKYIKKPPLTEKLLKKPPFRFLMDVFSNFIKQSGTFDGLYTPEEQMFENITSREDKIRFLQKMIDATKLTTKLDLKVRTSKIVAGQEPELTNELLQAMASVAEKNLEWDSIVDQVVIS---HSKTPLTLTKPPKETKNSSKNPSPAGKDEDAKRRKEKRISPQE-QKLRKVKEQVSRSTPPTEKDKASQKKSKAPKDETKLSRQNSKQKSPSPVKQKSKAKLQPSTESDNLSQSMSPVEEGSTKPAASESAPSKPEPEMVPPLKEKEAVVRPVQETPTAPPAEPESRKSSSRSRRSSG-------------------------------------SHRQPE------------------------------------------------------PNPIPNESQSQPAVQSSETSSPPETNSGEAKREVPLTRENSKEVN---QRPRTSLRPPSARPASARPGAPRRRNVEIVLQPNDQIKMSGINVKLETFGD--------LDDDGENLVIIEDSAAHDIVEGGGDEPALEGQLDAQGRLVQQILETQKELVNQGAEVEPPPAQAG----------RQTSARQVNDVRDVVQKLTKSIGPLGKLLDCIPEDFDAMQLELTMWRDTYTQASTELKREQTLTASATEPLQHQLQQIQASIAEYRELIDESRHKILQNNARILKLMMEQ------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: .**:.*** *::********.*****:* *::::.*: :* :.***. * :*:..:: ** **** **.. :.: * .:.::****:*** ****** :.. . .:*. *. * :*: . . : *. .:: .* . . .. : : . . . :* :: . . :.. .. .. .. : :: : . : :. : : .* : . . * :: * :: . : .: :. *: .. . . . : : .* :: . : *. . . . * * **.****..** :. : :. : .. :. .: : :::.: .* . :: : . : :* **::****:*: . . :. : . :: ::::: :* :*.: :* ****::* * **.*:** ** *:. : : * :** :* ..***: :* ::: * : :: * : :**:*: :* *:: . ", "identical_positions": 114, "similar_positions": 197, "identity": "16.06%" }, { "cls_id": "homologset.agr.RGD:1309253", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5PQN7-1", "uniprot_id": "LZIC_RAT", "id": "Q5PQN7-1", "name": "Protein LZIC", "aln": "MASRGKTETSKLKQNLEEQLDRLMQQLQDLEECREELDGDEYEETKKETLEQLSEFNDSLKKIMSGNMTLVDELSGMQLAIQAAISQAFKTPEVIRLFAKKQPGQLRTRLAEMDRDLMVGKLERDLHTQQKVEILTALRKLGEKLTDDDEAFLSANAGAVLSQFEKVSTELGSGDKVLALAGFEVEKAKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K3C3-1", "uniprot_id": "LZIC_MOUSE", "id": "Q8K3C3-1", "name": "Protein LZIC", "aln": "MASRGKTETSKLKQNLEEQLDRLMQQLQDLEECREELDADEYEETKKETLEQLSEFNDSLKKIMSGNMTLVDELSGMQLAIQAAISQAFKTPEVIRLFAKKQPGQLRTRLAEMDRDLMVGKLERELYTQRKVEILTALRKLGEKLTEDDETFLSANASAVLSQFEKVSTELGSGDKVLALAGFDVEKAKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WZA0-1", "uniprot_id": "LZIC_HUMAN", "id": "Q8WZA0-1", "name": "Protein LZIC", "aln": "MASRGKTETSKLKQNLEEQLDRLMQQLQDLEECREELDTDEYEETKKETLEQLSEFNDSLKKIMSGNMTLVDELSGMQLAIQAAISQAFKTPEVIRLFAKKQPGQLRTRLAEMDRDLMVGKLERDLYTQQKVEILTALRKLGEKLTADDEAFLSANAGAILSQFEKVSTDLGSGDKILALASFEVEKTKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DHH7-1", "uniprot_id": "LZIC_DANRE", "id": "Q6DHH7-1", "name": "Protein LZIC", "aln": "MASRGKSETSKLRQNMEEQLDRLMQQLQDLEECREDLEEEEYEETKKETLEQLSEFNDSLKKLMSGNMTLVDELGGMQLAIQAAISQAFKTPEVIRLFAKKQPGQLRTRLAEMDRDVMVGKLSRDVFTQQKVEILTALRKLGEKLTTEDEAFLAANASATLSHFEKVTASLGSEDKIMALASSGVGKTQT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******:*****:**:*******************:*: :**********************:***********.*****************************************:*****.*::.**:**************** :**:**:***.* **:****::.*** **::***. * *::.", "identical_positions": 155, "similar_positions": 28, "identity": "81.58%" }, { "cls_id": "homologset.agr.RGD:1309255", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P80098-1", "uniprot_id": "CCL7_HUMAN", "id": "P80098-1", "name": "C-C motif chemokine 7", "aln": "MKASAALLCLLLTAAAFSPQG------------------------------LAQPVGINTSTTCCYRFINKKIPKQRLESYRRTTSSHCPREAVIFKTKLDKEICADPTQKWVQDFMKHLDKKTQT--PKL--------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P13500-1", "uniprot_id": "CCL2_HUMAN", "id": "P13500-1", "name": "C-C motif chemokine 2", "aln": "MKVSAALLCLLLIAATFIPQG------------------------------LAQPDAINAPVTCCYNFTNRKISVQRLASYRRITSSKCPKEAVIFKTIVAKEICADPKQKWVQDSMDHLDKQTQT--PKT--------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q99616-1", "uniprot_id": "CCL13_HUMAN", "id": "Q99616-1", "name": "C-C motif chemokine 13", "aln": "MKVSAVLLCLLLMTAAFNPQG------------------------------LAQPDALNVPSTCCFTFSSKKISLQRLKSYV-ITTSRCPQKAVIFRTKLGKEICADPKEKWVQNYMKHLGRKAHT--LKT--------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P80075-1", "uniprot_id": "CCL8_HUMAN", "id": "P80075-1", "name": "C-C motif chemokine 8", "aln": "MKVSAALLCLLLMAATFSPQG------------------------------LAQPDSVSIPITCCFNVINRKIPIQRLESYTRITNIQCPKEAVIFKTKRGKEVCADPKERWVRDSMKHLDQIFQN--LKP--------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D4ABS1-1", "uniprot_id": "D4ABS1_RAT", "id": "D4ABS1-1", "name": "C-C motif chemokine", "aln": "MKIS-TLLCLLLIAAAISPQV------------------------------LAGPDSVFTPVTCCYNVAKQKIHIRRLKSYRKITSSQCPREAVIFRTVLDKELCADPKEKWVKDSMNHLDQKSRT--QHP--------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62401-1", "uniprot_id": "CCL12_MOUSE", "id": "Q62401-1", "name": "C-C motif chemokine 12", "aln": "MKIS-TLLCLLLIATTISPQV------------------------------LAGPDAVSTPVTCCYNVVKQKIHVRKLKSYRRITSSQCPREAVIFRTILDKEICADPKEKWVKNSINHLDKTSQTFILEPSCLG----------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AB32TC92-1", "uniprot_id": "A0AB32TC92_DANRE", "id": "A0AB32TC92-1", "name": "C-C motif chemokine", "aln": "MRRSCIFIASLVLVAFCSVVGSDWSQCKCCFSFSNARLPVQQVESCHTTNLLCNMNGSQGPEKCCFSFTNARIPLKQIESYY-TTHLQCNMNAVIFIIRAQREICTNPTEKWVRRLMKMVDNQNMKQMTEAGSVDSA--------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32T986-1", "uniprot_id": "A0AB32T986_DANRE", "id": "A0AB32T986-1", "name": "C-C motif chemokine", "aln": "MKPSCNFIACLVLATFCLVN------------------------------------GSQGPVKCCYSFFNARIPVKEVGGYH-ATHLQCNINAVIFITKAQREICTNPAEKWVQRLMRLVDVQNMKQMTEGRIGDSLDTHRSKPLHEMPKTNQAVSKKAEIITMTEMPLQQQDETTSILYYFQDWTDFDTTQANSKTDEHTNATSRWSQIHPSWIIINTGSLTAGTHQKERHIRQAHARGR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: * ::. *: .: . . .**: . . :* :.: .* * :* :**** :*:*::* ::**: : :. . . ", "identical_positions": 18, "similar_positions": 32, "identity": "7.47%" }, { "cls_id": "homologset.agr.RGD:1309256", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "G3V9C9-1", "uniprot_id": "G3V9C9_RAT", "id": "G3V9C9-1", "name": "", "aln": "------------------MNPMNPMKPALPPAPHGDGSFAYESVPWQQSATQPAG---SLSVVTTVWGVGNATQSQVLGNPMGPAGSPPGGSMMPGVAGGSSALTSPQCLGQQAFAEGGASKGYVQQGVYGR-------------------------GGYPGGSSFTPGYAG-GPGGLGLPTHAARPSTDFT-----QAAAAAAMAAAAATATATATATVAALQEKQSQ---------------------ELSQYGAMGTGQSFNSQFLQHGGPRGPSVPPGMNPSGMGGMM--GPSGLSSMAMNPTRAAGMTPLYAGQRLPQH----------------------------------------GYPGPPQGQPLPRQGVKRAY-SEVYPGQQYLQ------------GGQYAAS--TAQYAPGPGQPPGPASSYAGHRLPLQQG-MAQSLSAPGPTGL---HYKPTEQFNGQG-------ASFNGGSISYS----QPGLSGPSRSIP---------------------------------------------------------------AYPSSPLPGNPTPPMTPSSSAPYMSPSQEVKSPFLPDLKPGLSSLHPSPSGSVPCDELRLTFPVRDGVVLEPFRLQHNLAVSNHVFQLRDSVYKTLMLRPDLELQFKCYHHEDRQMNTNWPASVQVSVNATPLSIERGD-NKTSHKPLYLKHVCQPGRNTIQITVTACCCSHLFVLQLVHRPSVRSVLQGLLKKRLLPAEHCITKIKRNFSSGTIPG----TPGPNGEDGVEQTAIKVSLKCPITFRRIQLPARGHDCRHIQCFDLESYLQLNCERGTWRCPVCNKTALLEGLEVDQYMLGILIYIQNSDYEEITIDPTCSWKPVPVK-------PDLHIKEEPDG-------------------------------------PVLKRCRTVSPAHVLMPSVMEMIAALGPGAAPFAPLQPPSAPTPSDYPSQGSNFLGPG-----------------TFPESFPSATPATPNLAEFTQGPPPISYQSDIPSSLLTPDKSA-PCLPGQMAPAGHLDPAHNPGPPGLHTPNLGPTPGTQLHHPNPSPASRQPLGQPNTGPISELAFNPATGMMGPPSMTGAGEASEPALDLLPELTNPDELLSYLGP-PDLPT---------NSSDDLLSLFENN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CIE2-1", "uniprot_id": "ZMIZ2_MOUSE", "id": "Q8CIE2-1", "name": "Zinc finger MIZ domain-containing protein 2", "aln": "------------------MNPMNPMKPALPPAPHGDGSFAYESVPWQQSATQPAG---SLSVVTTVWGVGNATQSQVLGNPMGPAGSPPGGSMMPGVAGGSSALTSPQCLGQQAFAEGGASKSYVQQGVYGR-------------------------GSYPGGSSFTTGYAG-GPAGLGLPTHAARPSTDFT-----QAAAAAAMAAAAATATATATATVAALQEKQSQ---------------------ELSQYGAMGTGQSFNSQFLQHGGPRGPSVPPGMNPSGMGGMM--GPSGLSSMAMTPTRAAGMTPLYAGQRLPQH----------------------------------------GYPGPPQGQPLPRQGIKRAY-SEVYPGQQYLQ------------GGQYAAN--TAQYAPGPGQPPGPASSYAGHRLPLQQG-MAQSLSAPGPTGL---HYKPTEQFNGQG-------ASFNGGSISYS----QPGLSGPSRSIP---------------------------------------------------------------GYPSSPLPGNPTPPMTPSSNVPYMSPSQEVKSPFLPDLKPGLSSLHPSPSASVHCDELRLTFPVRDGVVLEPFRLQHNLAVSNHVFQLRDSVYKTLMLRPDLELQFKCYHHEDRQMNTNWPASVQVSVNATPLSIERGD-NKTSHKPLYLKHVCQPGRNTIQITVTACCCSHLFVLQLVHRPSVRSVLQGLLKKRLLPAEHCITKIKRNFSSGTIPG----TPGPNGEDGVEQTAIKVSLKCPITFRRIQLPARGHDCRHIQCFDLESYLQLNCERGTWRCPVCNKTALLEGLEVDQYMLGILIYIQNSDYEEITIDPTCSWKPVPVK-------PDLHIKEEPDG-------------------------------------PVLKRCRTVSPAHVLMPSVMEMIAALGPGAAPFAPLQPPSAPTPSDYPSQGSNFMGPG-----------------TFPESFPSATPTTPNLAEFTQGPPPISYQSDIPSSLLTPDKST-PCLPGQMAPAGHLDPAHNPGPPGLHTPNLGPTPGTQLHHPNPSPASRQPLGQPNTGPISELAFNPASGMMGPPSMTGAGEASEPALDLLPELTNPDELLSYLGP-PDLPT---------NSSDDLLSLFENN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NF64-1", "uniprot_id": "ZMIZ2_HUMAN", "id": "Q8NF64-1", "name": "Zinc finger MIZ domain-containing protein 2", "aln": "------------------MNSMNPMKPALPPAPHGDGSFAYESVPWQQSATQPAG---SLSVVTTVWGVGNATQSQVLGNPMGPAGSPSGSSMMPGVAGGSSALTSPQCLGQQAFAEGGANKGYVQQGVYSR-------------------------GGYPGAPGFTTGYAG-GPGGLGLPSHAARPSTDFT-----QAAAAAAVAAAAATATATATATVAALQEKQSQ---------------------ELSQYGAMGAGQSFNSQFLQHGGPRGPSVPAGMNPTGIGGVM--GPSGLSPLAMNPTRAAGMTPLYAGQRLPQH----------------------------------------GYPGPPQAQPLPRQGVKRTY-SEVYPGQQYLQ------------GGQYAPS--TAQFAPSPGQPPAPSPSYPGHRLPLQQG-MTQSLSVPGPTGL---HYKPTEQFNGQG-------ASFNGGSVSYS----QPGLSGPTRSIP---------------------------------------------------------------GYPSSPLPGNPTPPMTPSSSVPYMSPNQEVKSPFLPDLKPNLNSLHSSPSGSGPCDELRLTFPVRDGVVLEPFRLQHNLAVSNHVFQLRDSVYKTLIMRPDLELQFKCYHHEDRQMNTNWPASVQVSVNATPLTIERGD-NKTSHKPLYLKHVCQPGRNTIQITVTACCCSHLFVLQLVHRPSVRSVLQGLLKKRLLPAEHCITKIKRNFSSGTIPG----TPGPNGEDGVEQTAIKVSLKCPITFRRIQLPARGHDCRHIQCFDLESYLQLNCERGTWRCPVCNKTALLEGLEVDQYMLGILIYIQNSDYEEITIDPTCSWKPVPVK-------PDMHIKEEPDG-------------------------------------PALKRCRTVSPAHVLMPSVMEMIAALGPGAAPFAPLQPPSVPAPSDYPGQGSSFLGPG-----------------TFPESFPPTTPSTPTLAEFTPGPPPISYQSDIPSSLLTSEKST-ACLPSQMAPAGHLDPTHNPGTPGLHTSNLGAPPGPQLHHSNPPPASRQSLGQASLGPTGELAFSPATGVMGPPSMSGAGEAPEPALDLLPELTNPDELLSYLGP-PDLPT---------NNNDDLLSLFENN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B1Q3-1", "uniprot_id": "A0A8M2B1Q3_DANRE", "id": "A0A8M2B1Q3-1", "name": "", "aln": "------------------MNPINSMKPALPPTPHSDSSYPYDPVPWQQGPSQPAG---SLSVVTTVWGVTNPSASQVFGAPMGPGGNSAGGHMMP---GSSPGMNSPQFMSQQGYPE--PNKTYMQQGMYGRPS-----------------------GGYPAGPGYGGSYPNNGAGSLGMPPHGVRPPTDFT-----QAAAAAAVAAAAATATATATATVAALQEKQNQ---------------------ELS-YGPMGGASSYNTQFLSHSGPRGP---PGMSPSGMVGSR--PPS------MGPMYTQ------QGQRLPQHP---------------------------------------GYPGSQQGPPRHQQALKRPYNSEGFPGQQYGPGMG--------GGGPYPGQ--PMQYHGPGPQRSAPSPSYPTHRMPLQQPSMAQYPAGPGNPSQ---YYKQAEQFNGQGNNHSLSSAVTTGGYSSFN----QPTVNGPGRAMP---------------------------------------------------------------GYPSSPLPGNPTPPMTPGSSMPYMSPNQDVKSPFLHDVKPNISALQP-PTGN-PSDDLRLTFPVRDGVVLEPFRLEHNLAVSNHVFQLRDSVYKTLMMRPDLELQFKCYHHEDRQMNTNWPASVQVSVNATPLTIERGD-NKTSHKPLYLKHVCQPGRNTIQITVTACCCSHLFVLQLVHRPSVRSVLQGLMKKRLLPAEHCVTKIKRNFSSGTIPG----TPGLNGEDGVEQTAIKVSLKCPITFRRIQLPARGHDCRHIQCFDLESYLQLNCERGTWRCPVCNKTALLEGLEVDQYMLGILIYIQNSDYEEITIDPVCSWKPVPVK-------PDLHIKEDPDG-------------------------------------PALKRCRTLSPSHMILPSVMEMIAALGPASSPYQSLPAGGSSSTPDYPSQGGSGYSSQ-----------------PGFSDFP-NAPGTPTLGEFTPGPPPLSYQSDLPSGLLTPEKPVGHPMPGQMPHSSRMDPSHNP--LQQQQQQHQALHGSSSMGPGAPMHSR--------GPSQNPRMHTDSFGLGAP--GGPGDVSEPALDLLPELTNPDELLSYLGP-PDLPN---------NSNDDLLALFESN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A6J3SHB9-1", "uniprot_id": "A0A6J3SHB9_DROME", "id": "A0A6J3SHB9-1", "name": "", "aln": "MSEKVEQVKESRKEKVKEEITKDDSTSVLTFDPHPYFPFLFDPYSSSKYGSQVRERKIDRCLKQLQDALNGGKKNDEMNQQAGSSRAPATGGQISPPGATTVGVEQQQHLQQQHQQQYYNQQQQQQQQQYQQQHQRDNFLAYQQQQQQQQQQQQQLQRSGGGGGNFMLGNDLVGGDSLRSLNNTFGPNSEFTSLGGANSSASSSLSGLSSSSSQGYTGMVAASQQHQQQQPHHHQQQQQQQQQQHMGSMDAMGGYSQMGGGMHPGPNSGMMGNMNGQYMNGGSGQGGYNGAQGMGMGYGGGGSMGPQRHHQMTPMNQMQNMSMGPGVGGSGGMGGGMNPLQQQAAQQQMGGMNPMAKMQGMANGGYPQQAPPSLTQQQQQQQQRRMAPYPHPQMHMAQKRAAAGVGGAGGMYPGNPMQQQQAQMYGNQQMHPGSGGGVPLPMQAGGAGNGYGRSGPMGVGNGGYGRMSAGNGMGPTGGPVMGPMGPGGMTAGGMGPGPGCMSQQRFMPQGSGGGMPGVGYGGVGGAASHQGQFYPGSGQSAGMQQAGGMCPAGPGAVATTGNPYQNQGFQQNYQHSPVPGNPTPPLTPACSVPYVSPNPDIKPPMD------------------NSEEMRLTFPVRDGIILAPFRLLHNLSVSNHVFHLKQNVYNTLMCRNDLELQLKCFHQDDRQMNTNWPHTVTVSANATPLNIERSEKNSTALRPLYLKAVCQPGRNTLQLTASSCCCSHLFVLQLVHRPSVRQVLQTLHKRNLLPLEHSVQKIKRNLSQPEANAGPDATPQQQQQQGGGQQCAKISLKCPITKSRIRLPARGHECKHVQCFDLEAYLMINSERGSWRCPECSKSAITDTLEIDQYIWAILNTLGNSDVDEVIIDSSANWRALQHNGGMPNAPPPSNVPSNPSGGSGSNSGNGSVNPTLPVIKQELCDDIAKVMSPGSTQLPTWDSAQAMSPYNMHDMNSIASGNMMGNGGNTNQHGNRSSYDGFSGNHSDGSGGLPGGDGGVNSLDQLNAMEKSLSDQMPHTPHTPGAASHPMTPGGPPSVSSSHNEPISGGTPNANGSGSATNGSGNNNSSTGHNSPQTPGTPSRMGGGMGGSGSADSQQQQQEQLLNSLMSSQTQLKFSESDLSAELQSFDAAAAAINDTAHDLNLLQDVDPMEILSYLDPQPDLNTPPSSGSSNNNASDDLLATLFD-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : ...*. ** .: ::. . .: :* . .: .: . . .: :. *.. .. . :. . : .: . * : ** : .: ** * : . .. .: . * .* : * ::** :::*:::::. ::::: *. *** *::*.* :. *. ** . ..: .. .* * . * * . * * *.:. *** :* :: :* * ** *. . * : . * :*:* : . .* . * . ** * . * : . * . * :* * **:*******:**... **:**. ::*.*: .:::*********::* **** ***:******:*::.**:**: * *****:**:*::********* :* **.*****.***.: *.*: :***** ********:*:*.::******************.*** * *:.*** **.: *****:*. . ** : ::* * . *:******* **:******:*:*:******:** :*.***:**** *.*:*: : **:***: .** : *** :*: **. ..*:.: : * :: .:*.* *. . .:::** :: . : :* .. . . .. .:*.. . .. :* :.. . ***.:* . : * . *.: .. . :.* *. . .: . : : : . ... . * : .:* *:****.* *** . * .****: : . ", "identical_positions": 270, "similar_positions": 254, "identity": "22.41%" }, { "cls_id": "homologset.agr.RGD:1309257", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4A0J7-1", "uniprot_id": "D4A0J7_RAT", "id": "D4A0J7-1", "name": "", "aln": "MAYPLPLVLCFALVVARVWGSSTPPTGTSEPPDVQTVAPTEDDVLQNEADNQENVLSQLLGDYDKVKAVSEGSDCQCKCVVRPLGRDACQRINEGASRKEDFYTVETITSGSSCK-CACVAPPSAVNPCEGDFRLQKLREADSRDLKLSTIIDMLEGAFYGLDLLKLHSVTTKLVGRVDKLEEEVSKNLTKENEQIKEDVEEIRTELNKRGKENCSDNILGNMPDIRSALQRDAAAAYAHPEEQYEERFLQEETVSQQINSIELLRTQPLAPPTVMKPRQPSQRQVHLRGRLASKPTVIRGITYYKAKVSEEENDIEDQ----HDELFSGDSGVDLLIEDQLLRQEDLLMSATRRPATTR--HAAAVSTDASVQATALSSEPAQASASAPSLVDPASQAPDRQLLASPQTTTVSPETM---GVMPSTQVSPTTVAHTAIQP-----PPAMIPGDIFVEALHLVPMSPDTVGTDMAEEEGTARQEATSASPILSPEEEDDIRNVIGRCKDTLSTITGPTTQNTYGRNEGAWMKDPLAKDDRIYVTNYYYGNTLVEFRNLENFKQGRWSNSYKLPYSWIGTGHVVYNGAFYYNRAFTRNIIKYDLKQRYVAAWAMLHDVAY-EETTPWRWQGHSDVDFAVDENGLWLIYPALDDEGFSQEVIVLSKLNAVDLSTQKETTWRTGLRRNFYGNCFVICGVLYAVDSYNQRNANISYAFDTHTNTQIVPRLLFENEYSYTTQIDYNPKDRLLYAWDNGHQVTYHVIFAY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3V1G4-1", "uniprot_id": "OLM2B_MOUSE", "id": "Q3V1G4-1", "name": "Olfactomedin-like protein 2B", "aln": "MAYPLPLVLCFALVVAQVWGSTTPPTGTSEPPDVQTVEPTEDDILQNEADNQENVLSQLLGDYDKVKAVSEGSDCQCKCVVRPLGRDACQRINQGASRKEDFYTVETITSGSSCK-CACVAPPSAVNPCEGDFRLQKLREADSRDLKLSTIIDLLEGAFYGLDLLKLHSVTTKLVGRVDKLEEEVSKNLTKENEQIKEDVEEIRTELNKRGKENCSDNTLESMPDIRSALQRDAAAAYAHP--EYEERFLQEETVSQQINSIELLRTQPLVPPAAMKPQRPLQRQVHLRGRLASKPTVIRGITYYKAKVSEEENDIEEQ----HDELFSGDSGVDLLIEDQLLRQEDLLTSATRRPATTR--HTAAVTTDASIQAAASSSEPAQASASASSFVEPAPQASDRELLATPQTTTVFPEPT---EVMPSTQVSPTTVAHTAVQP-----LPAMVPGDIFVEALPLVPLLPDTVGTDMPEEEGTAGQEATSAGPILSPEEEDDIRNVIGRCKDTLSTITGPTTQNTYGRNEGAWMKDPLAKDDRIYVTNYYYGNTLVEFRNLENFKQGRWSNSYKLPYSWIGTGHVVYNGAFYYNRAFTRNIIKYDLKQRYVAAWAMLHDVAY-EEATPWRWQGHSDVDFAVDENGLWLIYPALDDEGFNQEVIVLSKLNAVDLSTQKETTWRTGLRRNFYGNCFVICGVLYAVDSYNQRNANISYAFDTHTNTQIVPRLLFENEYSYTTQIDYNPKDRLLYAWDNGHQVTYHVIFAY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q68BL8-1", "uniprot_id": "OLM2B_HUMAN", "id": "Q68BL8-1", "name": "Olfactomedin-like protein 2B", "aln": "MAKPRLLVLYFALIVVPAWVSSIVLTGTSEPPDAQTVAPAEDETLQNEADNQENVLSQLLGDYDKVKAMSEGSDCQCKCVVRPLGRDACQRINAGASRKEDFYTVETITSGSSCK-CACVAPPSALNPCEGDFRLQKLREADSQDLKLSTIIDMLEGAFYGLDLLKLHSVTTKLVGRVDKLEEEVSKNLTKENEQIKEDMEEIRTEMNKRGKENCSENILDSMPDIRSALQRDAAAAYAHP--EYEERFLQEETVSQQINSIELLQTRPLALPEVVKSQRPLQRQVHLRGRPASQPTVIRGITYYKAKVSEEENDIEEQ----QDEFFSGDNGVDLLIEDQLLRHNGLMTSVTRRPAATRQGHSTAVTSDLNARTAPWSSALPQPSTSDPSIANHASVGP------TLQTTSVSPDPTRESVLQPSPQVPATTVAHTATQQPAAPAPPAVSPREALMEAMHTVPVPPTTVRTDSLGKDAPAGWGTTPASPTLSPEEEDDIRNVIGRCKDTLSTITGPTTQNTYGRNEGAWMKDPLAKDERIYVTNYYYGNTLVEFRNLENFKQGRWSNSYKLPYSWIGTGHVVYNGAFYYNRAFTRNIIKYDLKQRYVAAWAMLHDVAY-EEATPWRWQGHSDVDFAVDENGLWLIYPALDDEGFSQEVIVLSKLNAADLSTQKETTWRTGLRRNFYGNCFVICGVLYAVDSYNQRNANISYAFDTHTNTQIVPRLLFENEYSYTTQIDYNPKDRLLYAWDNGHQVTYHVIFAY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7UVJ6-1", "uniprot_id": "A0A8N7UVJ6_DANRE", "id": "A0A8N7UVJ6-1", "name": "", "aln": "-MGLLLYIFCCVFCLTRANVEQQATDNTDN-----------RATLEDEMDNQENILTQLIGDYDKVKTLSEGSDCQCKCVVRPLSRSACKRIEEGQAKTEDFYTVETVTAGPNCKKCACIAPPSALNPCEGDFRFKKLQEAGQDDIKLSNIMDLLEGSFYGMDLLKLHSVTTKLLERVDNIEKSFSGNLTKEKVSVKGEKGQG-----KGARSNQRQEKKKRLSVLEPSLQKNAAAAFAHTERKYEEKFVGNQGPSKPV----LKKS---------KSEGQEEQHKPAKTKADAKNMSLRSMTFYKANRMEDSEGEERIGATVAHEVVSGDESVDLIIEDQLHKQG-LNTPVTTPEATVTVTQSTTINLNTQNFTTARMSNVTKQTQGQS--------------VKAMMSSTITTERP----TMPTSTTSTSTMTPGTNTT--------------TIATPLVVPKQLASVTVPIK-KSKLSWDEVTTQKSTTTLKTKD-----HGICKDTLASISDPVTHNKYGKNEGAWMKDPKGNGKVVYVTDYYYGNQLLEFRDIDTFKQGQVSNSYKLPYNWIGTGHVVYSGSFFYNRAFSRDIIRFDLRLRYVAAWTTLHDAILEEEEAPWTWGGHSDIDFSVDESGLWLVYPALDDEGFHQEVIILSKLRASDL--QKEKSWRTGLRRNYYGNCFVICGVLYAVDSFERTHANISYAFDTHTHTQMIPRLPFINNYTYTTQIDYNPKERMLYAWDNGHQVTYDVIFAY", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: .: :. . . .*.: *::* *****:*:**:*******::***************.*.**:**: * ::.********:*:*..** ***:*****:********::**:**.. *:***.*:*:***:***:************: ***::*:..* *****: .:* : : * .:.* :: :. :..:**::****:**. :***:*: :: *: : * :: *.. ::: : : :: :*.:*:***: *:.:. * .*..***..***:***** :: * ..* *:. :::::. : . ::. * .: : . . : :::: .: *:. ...:*:: : : : ** :* . :. : .*. . : : :* * *****::*:.*.*:*.**:********* .:.. :***:***** *:***:::.****: ********.*********.*:*:*****:*:**::**: ******: ***. ** :** * ****:**:***.****:********* ****:****.* ** ***.:********:****************::: :***********:**::*** * *:*:**********:*:************.*****", "identical_positions": 340, "similar_positions": 205, "identity": "44.5%" }, { "cls_id": "homologset.agr.RGD:1309260", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q4FZV3-1", "uniprot_id": "IDLC_RAT", "id": "Q4FZV3-1", "name": "Axonemal dynein light intermediate polypeptide 1", "aln": "-------MIPPADSLLKYDTPVLVSRNTEKRSPKARPLKVTVQQPGPSGAGPQPPKAKLPSTSCVPDPTKQAEEILNAILPPREWVEDTQLWIQQVSSTPSTRMDVVHLQEQLDLKLQQRQARETGICPVRRELYSQCFDELIREVTINCAERGLLLLRVRDEIRMTIAAYQTLYESSVAFGMRKALQAEQGKSDMERKITELETEKRDLERQVNEQKAKCEATEKRESERRQVEEKKHNEEIQFLKRTNQQLKAQLEGIIAPKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BVN8-1", "uniprot_id": "IDLC_MOUSE", "id": "Q8BVN8-1", "name": "Axonemal dynein light intermediate polypeptide 1", "aln": "-------MIPPADSLLKYDTPVLVSRNTEKRSPTARPLKVTIQQPGPSSTSPQPPKAKLPSTSCVPDPTKQAEEILNAILPPREWVEDTQLWIQQVSSTPSTRMDVVHLQEQLDLKLQQRQARETGICPVRRELYSQCFDELIREVTINCAERGLLLLRVRDEIHMTIAAYQTLYESSVAFGMRKALQAEQGKSDMERKITELETEKRDLERQVNEQKAKCEATEKRESERRQVEEKKHNEEIQFLKRTNQQLKAQLEGIIAPKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14645-1", "uniprot_id": "IDLC_HUMAN", "id": "O14645-1", "name": "Axonemal dynein light intermediate polypeptide 1", "aln": "-------MIPPADSLLKYDTPVLVSRNTEKRSPKARLLKVSPQQPGPSGSAPQPPKTKLPSTPCVPDPTKQAEEILNAILPPREWVEDTQLWIQQVSSTPSTRMDVVHLQEQLDLKLQQRQARETGICPVRRELYSQCFDELIREVTINCAERGLLLLRVRDEIRMTIAAYQTLYESSVAFGMRKALQAEQGKSDMERKIAELETEKRDLERQVNEQKAKCEATEKRESERRQVEEKKHNEEIQFLKRTNQQLKAQLEGIIAPKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VGG6-1", "uniprot_id": "IDLC_DROME", "id": "Q9VGG6-1", "name": "Putative inner dynein arm light chain, axonemal", "aln": "MEELDITSVGQFQTLVRYNNPVLVVKHPDKKG-GAPLTEIEMKRPQTAG--------------ALLDTKRETEEILNSILPPRCWEEDGQLWQQSVSSTPATRQDVINLQEMLDTRLQQTQARETGICPVRRELYSQCFDEIIRQVTINCSERGLLLLRIRDEIAMSMEAYETLYCSSVAFGMRKALQAHEEKEMLRDRVKTLELDKEALEEIIADMKLKQEQAERRNAELRASEEKKFTEEITFLKKTNAQLKAQLEGITAPKK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ::*::*:.**** ::.:*:. * :: ::* .:. .: *..:::*****:***** * ** *** *.*****:** **::*** ** :*** *********************:**:*****:********:**** *:: **:*** *************.: *. :. :: ** :*. **. : : * * * :*:*::* * ****..*** ***:** ********* ****", "identical_positions": 141, "similar_positions": 59, "identity": "53.21%" }, { "cls_id": "homologset.agr.RGD:1309261", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P57791-1", "uniprot_id": "FACE2_MOUSE", "id": "P57791-1", "name": "CAAX prenyl protease 2", "aln": "MAALGGDGLRLLSVSRPERQPESAALSGPGSGLCCWVSVFSCFSLACSYVGSLYVWKS--ELPRDHPAVIKRRSTSVLVVSSLSPLCVLLWRELTGIQPGTS--LLTLMGFRLEG----------IFPAALLPLLLTMILFLGPLMQLSMDCPCDLTDGLKVVLAPRSWARCLTDMRWLRNQVIAPLTEELVFRACMLP----MLAPCTGLGPAVFTCP-LFFGVAHFHHIIEQLRFRQSSVGSIFVSAAFQFSYTAVFGAYTAFLFIRT-GHLIGPVLCHSFCNYMGFPAVCAALEHP--QKWPLLAGYALGVGLFLLLLQPLTDPKLYGSLPLCMLLERTGASETLLCS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B0BMW8-1", "uniprot_id": "FACE2_RAT", "id": "B0BMW8-1", "name": "CAAX prenyl protease 2", "aln": "MAALGGDGLRLLSVSRPERQPESAALSSPGPGLCCWVSVFSCFSLACSYVGSLYVWKS--ELPRDHPAVIKRRFTSVLVVSSLSPLCVLLWRELTGIQPGTS--LLTLMGFRLEG----------IFPAALLPLLLTMILFLGPLMQLCMDCPCDLTDGLKVVLAPRSWARRLTDMRWLRNQVIAPLTEELVFRACMLP----MLAPCTGLGPAVFTCP-LFFGVAHFHHIIEQLRFRQSSVGSIFLSA----------------------GHLIGPVLCHSFCNYMGFPAVCAALEHP--QKWPLLAGYALGVGLFLLLLQPLTDPKLYGSLPLCMLLERTGASETLLCS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y256-1", "uniprot_id": "FACE2_HUMAN", "id": "Q9Y256-1", "name": "CAAX prenyl protease 2", "aln": "MAALGGDGLRLLSVSRPERPPESAALGGLGPGLCCWVSVFSCLSLACSYVGSLYVWKS--ELPRDHPAVIKRRFTSVLVVSSLSPLCVLLWRELTGIQPGTS--LLTLMGFRLEG----------IFPAALLPLLLTMILFLGPLMQLSMDCPCDLADGLKVVLAPRSWARCLTDMRWLRNQVIAPLTEELVFRACMLP----MLAPCMGLGPAVFTCP-LFFGVAHFHHIIEQLRFRQSSVGNIFLSAAFQFSYTAVFGAYTAFLFIRT-GHLIGPVLCHSFCNYMGFPAVCAALEHP--QRRPLLAGYALGVGLFLLLLQPLTDPKLYGSLPLCVLLERAGDSEAPLCS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AA70QJR3-1", "uniprot_id": "A0AA70QJR3_DANRE", "id": "A0AA70QJR3-1", "name": "CAAX prenyl protease 2", "aln": "----------MLSIKT-----LSDTFVG-----ECWISVSCCLLLACLYVGSLYVWKG--SLPRDHPNTIKRRFTSVLCVSAVAPLVVLAWTHSMKLRPSPP--LWALLGIRLEG----------FVPAAVLPLTLTMVLFLGPLTQLAVESPRGLFHDVKAGLNCQSWSKRVKDLKWLRNHVVAPLTEEFVFRACIIP----MLVPCTGPTSAIFISP-LFFGVAHFHHIIEQLRFGQDTVFDILICAAFQFTYTSVFGVYTAFIFIRT-GHLVGPVLCHSFCNRMGFPAIGSVLEHP--QKSLILLFYQLGVLLFFILLFPFTDPTFYGMSPVCSLLLTPRSACT----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9U1H8-1", "uniprot_id": "FACE2_DROME", "id": "Q9U1H8-1", "name": "CAAX prenyl protease 2", "aln": "--------MKNLSETEAEVTMQENVVHESLPQIPVATSVSCCFVLAVLYVGSLYIWST--KHNRDHPTTVKRRFASVSMVMLAAPFFVYFFSSPE-LLSRVP--FPKLLGLRLEG----------LWQAVVIPYSLTVLLFLGPIFVNMQN------ESVRSYFDLDYWRGSFGSIIWVRNHVIAPLSEEFVFRACMMP----LILQSFSPLVAVFITP-LFFGVAHLHHIAERLSLG-VELSTALLIGLFQFIYTTLFGFYSAFLFART-GHVMAPILVHAFCNHMGLPDLQDLWQQDLWRRVVAIILYLAGFVGWMFLVPLATDPSIYDNTLYWNA-------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03530-1", "uniprot_id": "RCE1_YEAST", "id": "Q03530-1", "name": "CAAX prenyl protease 2", "aln": "--------------------------------MLQFSTFLVLLYISISYVLPLYATSQPEGSKRDNPRTIKSRMQKLTIMLISNLFLVPFLQSQLSSTTSHISFKDAFLGLGIIPGYYAALPNPWQFSQFVKDLTKCVAMLLTLYCGPVLDFVLYHLLNPKSSILEDFYHEFLN-IWSFRNFIFAPITEEIFYTSMLLTTYLNLIPHSQLSYQQLFWQPSLFFGLAHAHHAYEQLQEGSMTTVSILLTTCFQILYTTLFGGLTKFVFVRTGGNLWCCIILHALCNIMGFPGPSRLNLHFTVVDKKAGRISKLVSIWNKCYFALLVLGLISLKDTLQTLVGTPGYRITL---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. : :: ** .** . **:* .:* * .: : : * . ::*: : : : ::* : . : : : . : .** :.**::**:.: : ::. :: . :* * ****:** ** *:* :: *:: :: *::** **:* : . . : ", "identical_positions": 37, "similar_positions": 61, "identity": "10.54%" }, { "cls_id": "homologset.agr.RGD:1309263", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "G3V979-1", "uniprot_id": "G3V979_RAT", "id": "G3V979-1", "name": "", "aln": "MWGRRQGRLRTLACGVEELRRRRREREAALRKARREQQLVSKRLLREDAPEETGGQSAAVLLGEAEVQQFLRLAQRGTDEKEREKALVSLRRGLQHPDTQQTFIRLEGSMRTLVGLLTSNRALLQLEAARCLHELSHSEQSAVAEACLPATSYLLTYLSGHSSDFIELCLYTLGNLIVESEAVRKQLLPQGIVPAFAACIQSPHVAVLEALGYALSQLLQAKEAPEKIIPSILDSSLPQQMLRLMGPGPKLNLGVAMEFAWCLHYIICSQVNNAVLLTHGALPTLVLLLVDLAGAVQRTDDVGLELLACPVVRCLSNLLTEVPAEAMGQQMELRDERLVAALFIFLQFFLQKQPALLPEGLWLLNNLTANSPTFCTSLLSLNLIEPLLQLLPLSNVVCMLVLTVLCNVVEKGPAYCQRLWPGPLLSCLLNTLALSDTDVVGQSLELLQLLFLYQPEAAHAFLQQSGLQALEKHQEETQLHDRIHALRQTTAILG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BQX5-1", "uniprot_id": "TMCO6_MOUSE", "id": "Q8BQX5-1", "name": "Transmembrane and coiled-coil domain-containing protein 6", "aln": "MWNRRQGRLRTLAFGVEELRRRRREREAALRKARREQQLVSKRLLREDAPEEVGGQSAAVLLGEAEVQQFLRLAQRGTDEKEREKALVSLRRGLQHPDTQQTFIRLEGSMRTLVGILTSNRALLQLEAARCLHELSHSEQSAVAEACLPATSYLLTYLSGHSSDFIELCLYTLGNLIVESEAVRKQLLPQGIVPAFAACIQSPHVAVLEALGYALSQLLQAKEAPEKIIPSILDSSLPQQMLWLMQPGPKLNLGVAMEFAWCLHYIICSQVNNAVLLTHGALPTLALLLLDLAGTVQRMDDVGLELLACPVLRCLSNLLTEVPAEVMGQQMELRDERLVAALFIFLQFFLQKQPALLPEGLWLLNNLTANSPTFCTSLLSLDLIEPLLQLLPLSNAVCMLVLTVLCNVVEKGPAYCQRLWPGPLLSCVLNTLALSDTEVVGQSLELLQLLFLHQPEAARAFLQQSGLQALEKLQEETQLQERIHALQQIAATHG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96DC7-1", "uniprot_id": "TMCO6_HUMAN", "id": "Q96DC7-1", "name": "Transmembrane and coiled-coil domain-containing protein 6", "aln": "MWSRRQGRLRPTVCGVEELRRRRREREAALRKARREQQLVSKRLLRNDAPEEAGEGCVAAILGETEVQQFLRQAQRGTEEKEREGALVSLRRGLQHPETQQTFIRLEGSMRTLVGLLTSNQALLQLEAARCLHELSHSEQSTVAEACLPATSYLLTYLSSHSSDFIELCLYTLGNLIVESEAVRRQLLPQGIVPALAACIQSPHVAVLEALGYALSQLLQAEEAPEKIIPSILASTLPQHMLQMLQPGPKLNPGVAVEFAWCLHYIICSQVSNPLLIGHGALSTLGLLLLDLAGAVQKTEDAGLELLACPVLRCLSNLLTEAAVETVGGQMQLRDERVVAALFILLQFFFQKQPSLLPEGLWLLNNLTANSPSFCTSLLSLDLIEPLLQLLPVSNVVSVMVLTVLCNVAEKGPAYCQRLWPGPLLPALLHTLAFSDTEVVGQSLELLHLLFLYQPEAVQVFLQQSGLQALERHQEEAQLQDRVYALQQT-ALQG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VR04-1", "uniprot_id": "Q9VR04_DROME", "id": "Q9VR04-1", "name": "Transmembrane and coiled-coil domain-containing protein 6", "aln": "-MKFKQMDFVTTTGEGSFLRNKIR---AYAKDHRVECRIKAKDSLRIG-LGQVKQEVAALEMGTKDVIGMASRIKRRKHATSEDLCRLSLG-FLQSNDNINAFAAIPGAIQVLVKELTGPHIQRQTDAVECLCNLSLGEAHVSEKIVTLAGSYMVTYLDGKAERLKRSCLWTLANVLGTCDKAGSVLLQMQIVPKLWRLYIEPN-------------------------------------------------GCQEDAAICLSLVAT--------------------------------------------RCPQHVSDEDRRYIGQNLPEKLHGQPASEYFMYIVHQLEIVT--------QEHKLDAQQAECLVRFFEATLASPADRLCLIYAVRVMTNLVALGDTS----LIFALADPQNLVQTLNQLFALRDPDLNLDAMRLLKNCLHLKVADSNLVLNSLQIYA-------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* : . . . **.: * * :. * * :: :* ** . :. .* :* :* : :* .. ...: . :** ** :. ::* : *:::.** **. : * :*..** :** .* . : * **::***..::. : . **:**.*:: .: . ** *** : .*: * : * ** : ** .:: * : . : .: *: : . :: . ::* *:.. . ::. * .* :* : . : *..* :. * *: : : :*: *.:: :::.**: : : . .*:. : * ", "identical_positions": 71, "similar_positions": 119, "identity": "14.37%" }, { "cls_id": "homologset.agr.RGD:1309264", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "F7F8V6-1", "uniprot_id": "F7F8V6_RAT", "id": "F7F8V6-1", "name": "", "aln": "MDLTLSRADYLQVGVTSQKTMKLLPTSRQRATQKVVIGDQDGVVMCFGMKKGEAVSVFKTLPGQKVSRLELGGALNTPQEKIFIAAGSEIRGFTKRGKQFLSFETNLTESIKAMYISGSDLFLSASYIYNHYCDCKDQNYYLSGDKINDVICLPVERLSRVTPVLACQDRVLRVLQGSDVTYEIEVPGPPTVLALHNGDGGDSGEGLLFGTSDGRLGLIQITASKPIHKWEIRNDKKRGGILCLDSFDIMGDGVKDLLVGRDDGMVEVYSFENANEPVLRFDQMLSESVTSVQGGCVGKDGYDEIVLATYSGWVTGLTTEPTHKESGPGEELKLNQEMQNKIASLRTELEHLQLKVLQERENYQQSSQSSQAKSTVPSFSINDKFTLNKDDASYSLVLEVRTAIDNVLIQ-------------------------SNDNFLLATYRCQANTTRLELKIRSIEGQYGTLQAYVTPRIQPKTCQVRQYHIKPLSLHQRTHFIDHDRPMNTLTLTGQFSFAEVHSWAVLCLPEVPEKPPAGECATFYFQNTFLDTQLECAYRKGEGIFKSDNISTISILKDVLSKEATKRKINLNISYEINEVSVKHTLKLIHPKLEYQLLLAKKVQLIDALKELQVHEGNTSFLIPEYRCILEEADHLQEEYKKQPAHLERLYGMITDLFIDKFKFKGTNVKTKVPVLLEILDSYDQNTLISFFDAA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K2G4-1", "uniprot_id": "BBS7_MOUSE", "id": "Q8K2G4-1", "name": "BBSome complex member BBS7", "aln": "MDLTLSRADYLQVGVTSQKTMKLLPTSRQRATQKVVVGDQDGVVICFGVKKGEAVPVFKTLPGQKISRLELGGAVNTPQEKIFIAAGSEIRGFTKRGKQFLSFETNLTESIKAMYISGSDLFLSASYIYNHYCDCKDQNYYLSGDKINDVICLPVEKLSRVTPVLACQDRVLRVLQGSDVMYEIEVPGPPTVLALHNGDGGDSGEGLLFGTSDGRLGLIQITTSKPIHKWEIRNDKKRGGILCVDSFDIMGDGVKDLLVGRDDGMVEVYSFENANEPVLRFDQMLSESVTSIQGGCVGKDGYDEIVLATYSGWVTGLTTEPTHKESGPGEELKLNQEMQNKISSLRSEIEHLQFKVLQERENYQQSSQSSQAKSTVPSFSINDKFTLNKEDASYSLVLEVRTAIDNVLIQSDVPIDLLDVDKNSAVVSFSSCDTESNDNFLLATYRCQANTTRLELKIRSIEGQYGTLQAYVTPRIQPKTCQVRQYHIKPLSLHQRTHFIDHDRPMNTLTLTGQFSFAEVHSWVVFCLPEVPEKPPAGECATFYFQNTFLDTQLECVYRKGEGVFKSDNISTISILKDVLSKEATKRKINLNISYEINEVSVKHTLKLIHPKLEYQLLLAKKVQLIDALKELQVHEGNTDFLTPEYRCILEEADHLQEEYKKQPAHLERLYGMITDLFIDKFKFKGTNVKTKVPMLLEILDSYDQNTLISFFDAA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IWZ6-1", "uniprot_id": "BBS7_HUMAN", "id": "Q8IWZ6-1", "name": "BBSome complex member BBS7", "aln": "MDLILNRMDYLQVGVTSQKTMKLIPASRHRATQKVVIGDHDGVVMCFGMKKGEAAAVFKTLPGPKIARLELGGVINTPQEKIFIAAASEIRGFTKRGKQFLSFETNLTESIKAMHISGSDLFLSASYIYNHYCDCKDQHYYLSGDKINDVICLPVERLSRITPVLACQDRVLRVLQGSDVMYAVEVPGPPTVLALHNGNGGDSGEDLLFGTSDGKLALIQITTSKPVRKWEIQNEKKRGGILCIDSFDIVGDGVKDLLVGRDDGMVEVYSFDNANEPVLRFDQMLSESVTSIQGGCVGKDSYDEIVVSTYSGWVTGLTTEPIHKESGPGEELKINQEMQNKISSLRNELEHLQYKVLQERENYQQSSQSSKAKSAVPSFGINDKFTLNKDDASYSLILEVQTAIDNVLIQSDVPIDLLDVDKNSAVVSFSSCDSESNDNFLLATYRCQADTTRLELKIRSIEGQYGTLQAYVTPRIQPKTCQVRQYHIKPLSLHQRTHFIDHDRPMNTLTLTGQFSFAEVHSWVVFCLPEVPEKPPAGECVTFYFQNTFLDTQLESTYRKGEGVFKSDNISTISILKDVLSKEATKRKINLNISYEINEVSVKHTLKLIHPKLEYQLLLAKKVQLIDALKELQIHEGNTNFLIPEYHCILEEADHLQEEYKKQPAHLERLYGMITDLFIDKFKFKGTNVKTKVPLLLEILDSYDQNALISFFDAA", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** *.* ***************:*:**:*******:**:****:***:*****..******* *::******.:***********.***************************:***********************:*****************:***:******************* * :**************:******.********:*.*****:***::****:*:********:*****:*********************:*******************:********.*****::************* ***********:********:***.*:**** ****************:***:****.*********:******:***:********* **************:*************************************************************************.*:**************.**************..******:*********************************************************************:*****.** ***:***********************************************:***********:********", "identical_positions": 624, "similar_positions": 58, "identity": "87.27%" }, { "cls_id": "homologset.agr.RGD:1309266", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZM29-1", "uniprot_id": "A0A8I5ZM29_RAT", "id": "A0A8I5ZM29-1", "name": "", "aln": "MGKRAG---GGAAAAAASASSGARLEPAAGRGGGPRSAAAGLLGALHLVMTLVVAAARAEKEAFIQSESIIEVLRFDDGGLLQTETTLGLSSYQQKSISLYRGNCRPIRFEPPMLDFHEQPVGMPKMEKVYLHNPSSEETITLVSISATTSHFHASFFQNRKILPGGNTSFDVVFLARVVGNVENTLFINTSNHGVFTYQVFGVGVPNPYRLRPFLGARVPVNSSFSPVINIHNPHSEPLQVVEMYSSGGDLHLELPTGQQGGTRKLWEIPPYETKGVMRASFSSRDADNHTAFIRIKTNASDSTEFIILPVEVEVTTAPGIYSSTEMLDFGTLRTQDLPKVLNLHLLNSGTKDVPITSVRPTPQNDAITVHFKPVTLKASESKYTKVASISFDASRAKKPSQFSGKITVKAKEKSYSKLEIPYQAEVLDGYLGFDHAATLFHIQDSP---ADPVER--PIYLTNTFSFAILIHDVLLPEEARTMFQVHNFSKPVLILPNESGYIFTLFFMPSTSSMHIDNNILLVTNASKFHLPVRVYTGFLDYFVLPPKIEER-----------FIDFGVLSATEASSILFAIINS-NPIELAIKSWHIIGDGLSIELVATERGNRSTVIASLPELEKSSLPDQSPVTLASGHFAVFRVKLTAKKLEGVHDGAIQITTDYEILTIPVKAVVAVGSLTCFPKHMVLPPSFPGKIVHQSLNVMNSFSQKVKIQQIRSLSEDVRFYYRRLRGNREDLEPGKKSKIANIYFDPGLQCGDHCYIGLP-FLSKSEPKVQPGVAMQEDLWDADWEAHQSLFKAWMGIKENAGHRLNAM-FEVNTDLQKNIISKVSAELSWPSVLSS-PRLVRFPLTNTNCSSEEEISVENPADVPVYVQFIPLALYSNPSVFADKLVSRFNLSKVAKLDLRT--LEFQVYRNSAHPLQSPTGFTEGLSRHFILNLILKPGEKKSVTVKFTPLHNRTVSSLIIVRNNLTVMDAVMVQGQGTTENLRVAGKLPGPGSSLRFKITEALLKDCIDRLKLREPNFTLKRTFKVENAGHLEIRVETIEISGYACEGYGFKVVNCQEFALSANASRDIVILFTPDFTASRVIRELKFVTSSGSEFVFVLNASLPYHMLAACAEALPRPNWELALYIIISGVMSALFLLVIGTAYLEAQGIWEPFRRRLSFEASNPPFDVGRPFDLRRIVGISSEGNLNTLG-CEHSHGRGFYSN--SSSRPGTGSHRQCGTSVHPHSSHGSKNSADVDNVRTRNSSSMSSRTSPQAATSQSTSKTSPLVSEAAAATQGHTASRKSKGAKQGQHNSQHHSHS--PLEQHSQP--PPPVPQHQEPPPERLSPAPLTHPPHPERASTTRHSSEDSDITSLIEAMDKDFEHHDSPSLDVFTEQPPSPLSK-----NKGKGKSLQQRKAKPPKKQEEKEKRGKGKPQEEELKDTLAD-DDSSSTTTETSNPDTEPLLREDTEKHKGRPAMP----EKQESELSQGKPKSKKLLNAKKEIPTDVKGGSFELPYTPSLENKQRRSLS-KIPLPTTLTSGSKSRNPQKTKGTDKLVGSRPAALSKLLPNS--QELSSTSSSEGEKDSPPPEWDAVPVHKPSSSTDSLYKLSLQTLNADIFLKQRQTSPTPASP-LPTAPCPFTSRGSYSSVVNSSGS-DTKAKQPNGSKSKLTKAASLPGKNGNPTFAAVAAGYDKSPGGNGFAKISSNKSEFSSSLGISHIP-VDSDGSDSSGLWSPVSNPSSPDFTPLNSFSAFG--NSFNLTGAVFSKL--SRSCSQSSQRSWNELSSGPSYLWDAPAADPSPSWPVPASSSSTTHTATSILGNTSGLWSTTPFSSSIWSSNINSNLPFSTPTNTLSGIGLMGTENSTPAHAP-ASSPADDLGQTYNPWRI-WSPTIGRRSSDPWSNSHFPHEN----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70472-1", "uniprot_id": "TM131_MOUSE", "id": "O70472-1", "name": "Transmembrane protein 131", "aln": "MGKRAGG--AAAAAAAASTSSAAGLEPAAGRGGGPRSAAAGLLGALHLVMTLVVAAARAEKEAFIQSESIIEVLRFDDGGLLQTETTLGLGSYQQKSISLYRGNCRPIRFEPPMLDFHEQPVGMPKMEKVYLHNPSSEETITLVSISATTSHFHASFFQNRKILPGGNTSFDVVFLARVVGNVENTLFINTSNHGVFTYQVFGVGVPNPYRLRPFLGARVPVNSSFSPIINIHNPHSEPLQVVEMYSSGGDLHLELPTGQQGGTRKLWEIPPYETKGVMRASFSSREADNHTAFIRIKTNASDSTEFIILPVEVEVTTAPGIYSSTEMLDFGTLRTQDLPKVLNLHLLNSGTKDVPITSVRPTPQNDAITVHFKPVTLKASESKYTKVASISFDASRAKKPSQFSGKITVKAKEKSYSKLEIPYQAEVLDGYLGFDHAATLFHIQDSP---ADPVER--PIYLTNTFSFAILIHDVLLPEEARIMFQVHNFSQPVLILPNESGYIFTLFFMPSTSSMHIDNNILLVTNASKFHLPVRVYTGFLDYFVLPPKIEER-----------FIDFGVLSATEASSILFAIINS-NPIELAIKSWHIIGDGLSIELVATERGNRSTVIASLPELERSSLPDQSPVTLASGHFAVFRVKLTAKKLEGVHDGAIQITTDYEILTIPVKAVIAVGSLTCFPKHMVLPPSFPGKIVHQSLNIMNSFSQKVKIQQIRSLSEDVRFYYKRLRGNREDLEPGKKSKIANIYFDPGLQCGDHCYIGLP-FLSKSEPKVQPGVAMQEDLWDADWDAHQSLFKAWMGIKENAGHRLNAM-FEVNTDLQKNIVSKVSAELSWPSVLSS-PRLLKFPLTNTNCSSEEEISLENPADVPVYVQFIPLALYSNPSVFADKLVSRFNLSKVAKLDLRT--LEFQVYRNSAHPLQSPTGFTEGLSRHFILNLILKPGEKKSVKVKFTPLHNRTVSSLIIVRNNLTVMDAVMVQGQGTTENLRVAGKLPGPGSSLRFKITEALLKDCIDRLKLREPNFTLKRTFKVENTGQLEIRVETIEISGYACEGYGFKVVNCQEFALSANASRDIVILFTPDFTASRVIRELKFVTSSGSEFVFVLNASLPYHMLAACAEALPRPNWELALYIIISGVMSALFLLVIGTAYLEAQGIWEPFRRRLSFEASNPPFDVGRPFDLRRIVGISSEGNLNTLG-CEHSHGRGFYSN--ASSRPGTGSHRQCGTSVHPHSSHGSKNSADVDNVRTRNSSSMSSRTSPQAAASQSTSKTSPLVSETAAATQGHTASRKSRGAKQGQHSSQHHSHSHSPLEQHSQP--PPPVPQHQEPPPERLSPAPLTHPSHPERASTTRHSSEDSDITSLIEAMDKDFDHHDSSPLDVFTEQPPSPMSK-----SKGKGKSLQQRKAKPPKKQEEKEKRGKGKPQEDELKDALAD-DDSSSTTTETSNPDTEPLLREDTEKHKGRPAVP----EKQESELSQGKPKSKKLLNAKKEIPTDVKGSSFELPYTPSLENKQRRNLPTKIPLPTTLASGSKSRNPPKTKGTNKLVENRPVALSKFLPSS--QELGNTSSSEGEKDSPPPEWDAVPVHKPSSSTDSLYKLSLQTLNADIFLKQRQTSPTPASPSLPTAPCPFTSRGSYSSVVNSSGS-DTKAKQTSSSKSKLTKAASLPGKNGNPTFAAVAAGYDKSPGGNGFAKISSNKSDFSSSLGISHIP-VDSDGSDSSGLWSPVSNPNSPDFTPLNSFSAFG--NSFNLTGAVFSKL--SRSCSQSSQRSWNEFNSGPSYLWDSPATDPSPSW--PASSSSPTHTATSILGNSSGLWSTTPFSSSIWSSNINSNLPFSTPTNALSSISLMGTENSAAAHTPSASGPADDLGQTYNPWRI-WSPTVGRRSSDPWSNSHFPHEN----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92545-1", "uniprot_id": "TM131_HUMAN", "id": "Q92545-1", "name": "Transmembrane protein 131", "aln": "MGKRAGGGATGATTAAVSTSAGAGLEPAAARSGGPRSAAAGLLGALHLVMTLVVAAARAEKEAFVQSESIIEVLRFDDGGLLQTETTLGLSSYQQKSISLYRGNCRPIRFEPPMLDFHEQPVGMPKMEKVYLHNPSSEETITLVSISATTSHFHASFFQNRKILPGGNTSFDVVFLARVVGNVENTLFINTSNHGVFTYQVFGVGVPNPYRLRPFLGARVPVNSSFSPIINIHNPHSEPLQVVEMYSSGGDLHLELPTGQQGGTRKLWEIPPYETKGVMRASFSSREADNHTAFIRIKTNASDSTEFIILPVEVEVTTAPGIYSSTEMLDFGTLRTQDLPKVLNLHLLNSGTKDVPITSVRPTPQNDAITVHFKPITLKASESKYTKVASISFDASKAKKPSQFSGKITVKAKEKSYSKLEIPYQAEVLDGYLGFDHAATLFHIRDSP---ADPVER--PIYLTNTFSFAILIHDVLLPEEAKTMFKVHNFSKPVLILPNESGYIFTLLFMPSTSSMHIDNNILLITNASKFHLPVRVYTGFLDYFVLPPKIEER-----------FIDFGVLSATEASNILFAIINS-NPIELAIKSWHIIGDGLSIELVAVERGNRTTIISSLPEFEKSSLSDQSSVTLASGYFAVFRVKLTAKKLEGIHDGAIQITTDYEILTIPVKAVIAVGSLTCFPKHVVLPPSFPGKIVHQSLNIMNSFSQKVKIQQIRSLSEDVRFYYKRLRGNKEDLEPGKKSKIANIYFDPGLQCGDHCYVGLP-FLSKSEPKVQPGVAMQEDMWDADWDLHQSLFKGWTGIKENSGHRLSAI-FEVNTDLQKNIISKITAELSWPSILSS-PRHLKFPLTNTNCSSEEEITLENPADVPVYVQFIPLALYSNPSVFVDKLVSRFNLSKVAKIDLRT--LEFQVFRNSAHPLQSSTGFMEGLSRHLILNLILKPGEKKSVKVKFTPVHNRTVSSLIIVRNNLTVMDAVMVQGQGTTENLRVAGKLPGPGSSLRFKITEALLKDCTDSLKLREPNFTLKRTFKVENTGQLQIHIETIEISGYSCEGYGFKVVNCQEFTLSANASRDIIILFTPDFTASRVIRELKFITTSGSEFVFILNASLPYHMLATCAEALPRPNWELALYIIISGIMSALFLLVIGTAYLEAQGIWEPFRRRLSFEASNPPFDVGRPFDLRRIVGISSEGNLNTLS-CDPGHSRGFCGAGGSSSRPSAGSHKQCGPSVHPHSSHSNRNSADVENVRAKNSSSTSSRTSAQAASSQSANKTSPLVLDSNTVTQGHTAGRKSKGAKQSQHGSQHHAHS--PLEQHPQPPLPPPVPQPQEPQPERLSPAPLAHPSHPERASSARHSSEDSDITSLIEAMDKDFDHHDSPALEVFTEQPPSPLPK-----SKGKGKPLQ-RKVKPPKKQEEKEKKGKGKPQEDELKDSLAD-DDSSSTTTETSNPDTEPLLKEDTEKQKGKQAMP----EKHESEMSQVKQKSKKLLNIKKEIPTDVKPSSLELPYTPPLESKQRRNLPSKIPLPTAMTSGSKSRNAQKTKGTSKLVDNRPPALAKFLPNS--QELGNTSSSEGEKDSPPPEWDSVPVHKPGSSTDSLYKLSLQTLNADIFLKQRQTSPTPASPSPPAAPCPFVARGSYSSIVNSSSSSDPKIKQPNGSKHKLTKAASLPGKNGNPTFAAVTAGYDKSPGGNGFAKVSSNKTGFSSSLGISHAP-VDSDGSDSSGLWSPVSNPSSPDFTPLNSFSAFG--NSFNLTGEVFSKLGLSRSCNQASQRSWNEFNSGPSYLWESPATDPSPSW--PASSGSPTHTATSVLGNTSGLWSTTPFSSSIWSSNLSSALPFTTPANTLASIGLMGTENSPAPHAPSTSSPADDLGQTYNPWRI-WSPTIGRRSSDPWSNSHFPHEN----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BDB2-1", "uniprot_id": "A0A8M2BDB2_DANRE", "id": "A0A8M2BDB2-1", "name": "", "aln": "--------------MASKDTTQSSLHPTR-----TKSACVGLL---RLLFIAFIHVAQANKQAFIQSDNILEVLHFGDGSLLQTESDIDLSSYRQKSASSQRGNSRPIRFEPPMLDFHEQPVGMPKMEKVYLHNPSSEE-ISLISISATTSHFHASFFQNRIIPPGGNTSFDVVFLARVVGNVENTLFINTSHHGVFTYQVFGVGVPNPYRLRPFVGARVPVNSSFSPLISIFNPHSEPLQVVEMYTSGGDLHLELPTGQQGGTKKLWEIAPFETKGVMRASFSSRDADNHTAFIRIKTNASNEDEFIILPVEVEVTTAPGIYSSTEMLDFGTLRSQDRPKQLNLHLLNSGAKDVSIMSVRPTPSNEAVTVEFKPITLKAGESRYTKVASISFDASKARRSDQFSGKITVKAKEKSYSKLEIPYQAEVLEGYLGFDHTATLFHIRDSP---VDPVDR--PIYLTNTFNFAIRIHNVSLPEEAKTMFNVHNFSTPVLIPPHESRYIFSLLFRPVRPSIHIDSNILLITNASKFHLPVRAYTGFLEPVVLPPCLQEH-----------ILDFGVLSATDTSSLVFVVVNS-NPIELEIKSWLVTGDSLSMELLNTERGNRSIALSRIQELQNTSAAQYKTVILASGYYAAFKVTLVAKALEGIYDGAVHITTDYEILTIPVKALIAVGTLSCSPKHIILPDAFPGKVVHQGLSIQSSFSQKVRLQQIRSLTEDVRFQYKRVRNNKVELEPRRKSKIANIYFDASLQCGDHCYVGLP-FVLKSESRPH-GLVMQEDMWDADVDLHQRLLKRWRELKEQSGHEVEAF-FEVDTDLQKNVQAKISAKLKWPSLLNSTLQQIHFPLTNTNSSSEEEVILENSADVPVYVQVLPLALYPNPSVFTGKLADRFPLGKLSNINLDTNTLEFLVQKNHSSVMKSSTGFVEGSTRPYVYNMLLMPGEVKSFNVRFRPTTNHSVSSLLVVRNNLTIVDLIMVHGQGTTESLRLAGKAPGLGSSLRFKLTESFLKDCS-EVKAKEPNFTLRRTFRLENTGLLPIHIRSVEISGNACEGYGFKVLNCEEFALKPNTSKDLIILFTPDFTSSRVIRELKLVTAGGSVFAFVLNASLPYHMLAVCAEMLPRPNWELELYIIVSLVMSSMFLLVIATAYLEAQGIWEPFKRRLSVES-NSPMETGKPFDLREIVRIQSDPNLNDFADSNQNSTRGMYGS----SIGGRAGGRQSG-------SHSSSNS---------NGVLPDSKPRSGSGRSGSMQSSSTFSLKDNGPGLNQVTNRKARSSKQQQQGSG------------------------------LLEDLPSTGPSQSN--SARVNSTEDQDYNRLLVAMDKDLDRPESPAINVSSEHNSQQSSQNKVLESKGKNETKVKNKTKALKKKEEKERKTKGKTQGEDFKEPLADNDDSSSTTTETSNPDVEANIKEEPVKVKGKTVAIDNGKEREEITPSPTKPKSKKQPTTKKENPVE-KSSSLELPYVTPLE-KQDKRKNFKTLASTAIPGVSKPRALSKLVN-AKMGDDRPSPLGKFVSNGSMPELGHSSGSEGEKESPPPEWD-VPLNKNGNQADSLQQISMQTMHADPFLKGPSSVINRTCSPPPTSPS-LVPHGSYSSMMHPSSE----INLKKAPGNKLTKSASLPGQNGNPTFAAVAAGYDKSPGGSGCASKADG----LGKVALPHMTSVESDGSDSSGLWSPVDSTSSPSFNQVNAFSAFGPNNPLNLSG-VFRGMTVPKSSE--SQQSWPEYTPVSPSIWDTETDN---SW--TTITGSPATPTTSILGSARSPWS---FSSSIWSTGNDSTLHSFSPPATSTLPDLVS-------HTAPPTPAPNDMGRTYNPWSMGWSPSLNRWNSEPWPNSPDNNNGI---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V7H4-1", "uniprot_id": "TM131_DROME", "id": "Q9V7H4-1", "name": "Transmembrane protein 131 homolog", "aln": "--------------------------------------------------MPTQVQMRPLLRIFAEPILLILIFLFTLGAKGEKVLQETFLGLQEAPIHDLG----DLRLVPSRLDFGTWSVGQARSQTVTLFNQHSNRTLQLNAVAGPSPAFYSSFLGTREVPPQGNTTFNVVFLPRQLGAIAADLLIHTS-FGQAELAVQGEGSECPYRLKPLVGIKAPMNATLTPEIHMYNPHERPLQILEIYSSGGEFQLELPSGGSEGPQNLWKIPPHTLKPVIRISFHGRTAGNHSAYIRIKVAEQELD--IFIPVEFEILPRHSVYARNPLADFGRVATLNAPDALQFKLDVRNDESRQLFGSYLR--------QIPGLSFDANNTSIVLDASL-FEGDEIINDLLVINSNQSSTSPGADQPFTVLVRAEIFHGGLTFDRNATRFVTTSPEGVEGEPLERKRSLVVRNKFAIPLMLFNVSLTEPIDESILEVTLVGDPRILIQPDESVELLRLNLLNDQVPFKSFLRIETNVTVFKLPLVSCSGRLHVSTQPIVLNFRQESLEKAAYNLELDLGTVPFAEMSRDGFVILRNDNPVPVRITNWFFKHP-KTVYSQSTFLGCRATAIGHPVSVENDTKGWHLCTEIRAGESAVFKVAIQTYEADATFG-TLKVWTPYEVIRVRVKFEASVGHLEIDQEQLSFKNCFPGKMCTAVLSIRSSFTHPVHVKGIS-FALPVGLRFKDFNAKGTTIAPQTLTKVGRIYFDPASVCRNNCYIRESTNDLAIFPSVPGGGNGNSGVINNNLLYDGVELRQRTELFRQLRRQLSSMSLTLHSEELPPLELDFSITIEWP-------KLVQFQPIPPTPAIEVGQVQR---------QWITLTNPSQSPLLLDYFLSDPAFARRTQLSLPH---EVIDVSSTSCYLTDKEVFSLPEAG---DPILLPGGASLTIPITFSAQLPEKYCTLLHVRSNLTLYEAVWLQARAVQSQFRFGNRRPGAASPLLFEMATNQFQGCQ----SGNEAVVVTRSFTARNSGVIPIRIEGFLIGSLPCEDFGFKVMDCAGFDLGENEARKVEIAFSADFTTSAVKRSLTLLTNLTYDISYKLLAQMPAESVELCASLLVRPGWESSLKNAALVVLLASFGLVLVAAVFDAKAIMVQQN---AYDAARNKGPLQPTFNLRNIVKLQAEEAAAKAESVQQQQK-------------------------------------------VKNGQLKELRKRTVVNSTNSKSKS----------------------------------------------------------------------------------KSSWSPWSMDMNALSKHLQKAKPKTVVSTPVTPPAASAP--------AAAPVPLPEAKPVKKSSTPSPQGVPISVQVRPQKKVKP-TPAVVLGTTKPKQEVSTPVADQHEKSLAKSSPP----QQENISPKPNKPPEQRVLKEQ---------------------------------------------------------------------NGSAKKMGKTPGRERERERRSKDQKLTNGTGAGVGFRKPERKQRQKLNFGQTTNSTSPPESPDALKCISNPWETSSRVSFRDVLR------------------------------TPQMAPTDNGFDWNHATS------------SSDLGPIGDNRKNATPPMVTSLWEPLSATASNSLFANTEVDFIT-----------------PDAIYEQREREKPQWEQRSDLVMRQQLLLQQPQKLEFQLRQQEKISLLANMDPSNWATNWSPLGYSTWPNATAGIGVMRPPPGLEQSARQTHNLAQEQVSAGPASGTGAALHGESLPTQYDPFTSPSSIWSDTWRQSSQRNNHNHMN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . * :. :: :: * *. :. : . :: . :*: *. *** .** .: :.* *.* *:. : * :::..:. *::**: .* : * ***:*:****.* :* : *:*:** .* * * * ****:*::* :.*:*::::* * :.***..***::*:*:***:::****:* . *.::**:*.*. * *:* ** .* *.**:*:****. .: *::***.*: . .:*: . : *** : : : *. *:::* . :. : . .: :::.*.:: . **: *:... . . .. .:. : . : : :**::.* * **: ** * .. :*::* .: : *.* :.: :.:* *.* : .: * : . : * : .: :.. : : **.: *:**: :* *. . * :: : :*:*.:. :: * *.::.. **: : *..* . :: . * *: :. ..:. : . : :* *.*:* : : :. .. :::: * **:: : ** :** * ::: : .****: *.: .**:: *::: * :: * : :: .. : : * :*:..****.. * ::**: . . * :..: : : . :: : .: :.:.:: : :.:: : ..: :.** : ::* .. : * . * :.*: .:..:: . : . :.: :::.* *. . : : . * : ::* * :. : * . .. .:*: **.***: : : ::.:.. ..:*...: ** .*.* *::: ::.* : ..: *:* .*:* : *::. . *.. .**.:****::* * * * ::.: * *:.***:* * *.*.::* : : * *.:* . : **. * **.** * :: : * **: :* ::*:.* . : :: . .*:**.** :.:: : *. . : . : * ..: .:. . . : *:.*.::: .. .: . . . . :.*. **.. . : . :. : : * ..: :... : :: * .: ::.: . * .:: . : .. ::. :.. * *:: . : . . . . : . *.:: . : .. . . : * .: *: .::. .* :*.. *:* . . . ..:. :: . :.**.*:. . * .: . .. : . : ::. : . : . . . : :. : . :. * *.. . .*. : .: . : * .: . *:.* :* :: ", "identical_positions": 270, "similar_positions": 577, "identity": "13.98%" }, { "cls_id": "homologset.agr.RGD:1309267", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5BJQ6-1", "uniprot_id": "CSTF1_RAT", "id": "Q5BJQ6-1", "name": "Cleavage stimulation factor subunit 1", "aln": "----MYRTKVGLKDRQQLYKLIISQLLYDGYISIANGLINEIKPQSVCAPSEQLLHLIKLGMENDDTAVQYAIGRSDTVAPGTGIDLEFDADVQTMSPEASEYETCYVTSHKGPCRVATYSRDGQLIATGSADASIKILDTERMLAKSAMPIEVMMNETAQQNMENHPVIRTLYDHVDEVTCLAFHPTEQILASGSRDYTLKLFDYSKPSAKRAFKYIQEAEMLRSISFHPSGDFILVGTQHPTLRLYDINTFQCFVSCNPQDQHTDAICSVNYNPSANMYVTGSKDGCIKLWDGVSNRCITTFEKAHDGAEVCSAIFSKNSKYILSSGKDSVAKLWEISTGRTLVRYTGAGLSGRQVHRTQAVFNHTEDYILLPDERTISLCCWDSRTAERRNLLSLGHNNIVRCIVHSPTNPGFMTCSDDFRARFWYRRSTTD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99LC2-1", "uniprot_id": "CSTF1_MOUSE", "id": "Q99LC2-1", "name": "Cleavage stimulation factor subunit 1", "aln": "----MYRTKVGLKDRQQLYKLIISQLLYDGYISIANGLINEIKPQSVCAPSEQLLHLIKLGMENDDTAVQYAIGRSDTVAPGTGIDLEFDADVQTMSPEASEYETCYVTSHKGPCRVATYSRDGQLIATGSADASIKILDTERMLAKSAMPIEVMMNETAQQNMENHPVIRTLYDHVDEVTCLAFHPTEQILASGSRDYTLKLFDYSKPSAKRAFKYIQEAEMLRSISFHPSGDFILVGTQHPTLRLYDINTFQCFVSCNPQDQHTDAICSVNYNPSANMYVTGSKDGCIKLWDGVSNRCITTFEKAHDGAEVCSAIFSKNSKYILSSGKDSVAKLWEISTGRTLVRYTGAGLSGRQVHRTQAVFNHTEDYILLPDERTISLCCWDSRTAERRNLLSLGHNNIVRCIVHSPTNPGFMTCSDDFRARFWYRRSTTD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q05048-1", "uniprot_id": "CSTF1_HUMAN", "id": "Q05048-1", "name": "Cleavage stimulation factor subunit 1", "aln": "----MYRTKVGLKDRQQLYKLIISQLLYDGYISIANGLINEIKPQSVCAPSEQLLHLIKLGMENDDTAVQYAIGRSDTVAPGTGIDLEFDADVQTMSPEASEYETCYVTSHKGPCRVATYSRDGQLIATGSADASIKILDTERMLAKSAMPIEVMMNETAQQNMENHPVIRTLYDHVDEVTCLAFHPTEQILASGSRDYTLKLFDYSKPSAKRAFKYIQEAEMLRSISFHPSGDFILVGTQHPTLRLYDINTFQCFVSCNPQDQHTDAICSVNYNSSANMYVTGSKDGCIKLWDGVSNRCITTFEKAHDGAEVCSAIFSKNSKYILSSGKDSVAKLWEISTGRTLVRYTGAGLSGRQVHRTQAVFNHTEDYVLLPDERTISLCCWDSRTAERRNLLSLGHNNIVRCIVHSPTNPGFMTCSDDFRARFWYRRSTTD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QFK9-1", "uniprot_id": "F1QFK9_DANRE", "id": "F1QFK9-1", "name": "Cleavage stimulation factor subunit 1", "aln": "----MFRPKPTLKDRQHLYKLIISQLLYDGYTIIANSLISEVKPQNVVSPSEQLMQLAKIGMENDDSAVQYAIGRSDTVAPGVGIDLEFDADVQTMSPEASEYETCYVTSHKGPCRVATYSRDGQLIATGSADASIKILDTERMLAKSAMPLEVMMNETAQQNMENHPVIRTLYDHVDEVTCLSFHPTEQILASGSRDYTLKLFDYSKPSAKRAFKHVQEAEMLRSISFHPSGDFLLVGTQHPTLRLYDVNTFQCFVSCNPLDQHTDTICGVCYNPSANSYVTCSKDGSIKLWDGVSNRCVTTFDKAHEGAEVCSAVFSKNSKYILSTGKDSVAKLWEISTGRTLVKYTGAGLSGRQTHRTQGVFNHTEDYVLLPDERTISLCCWDSRTAERKNLLSLGHNNIVRCIVHSPTNPGFMTCSDDFRARFWYRRTTTD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V9V0-1", "uniprot_id": "Q9V9V0_DROME", "id": "Q9V9V0-1", "name": "Cleavage stimulation factor subunit 1", "aln": "MRDEILDPSNLVKNREILYRLMISQLMYDGLEKFAMELSMLVK-ADQCAPSERLLHVMIAGMQ---TLSDKDKTNSDDVLP--GIDLEFEPEASALAPEPHSYETAYVTSHKQACRAGAFSCDGSLVATGSVDASIKILDVERMLAKSAP--EDIEPGREQQ---GHPVIRTLYDHTDEVSYLEFHPKEHILASASRDGTVKLFDIAKPSVKKAHKVFTDCEPVLCLSFHPTGDYVAIGTEHNVLRVYDVATTQCFVSAIPSQQHKAGVTCVKYSPTGKLYATGSYDGDIKIWDGISGRCINTIAEAHGGAAICSLEFTRNGKYLLSSGMDSLVYLWELCTSRPIQTYTGAGTTGKQEHQTEAVFNHTEDYVLFPDEATTSLCSWNSRNGCRLTLNSLGHNGPVRYITHSPNGPAFLTCSDDFRARFWYRRANNQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .. :*:*: **:*:****:*** :* * :* . :***:*::: **: : : .** * * ******:.:..:::**. .***.****** .**..::* **.*:****.********.******** * : ** .**********.***: * ***.*:****.*** *:**** :***.*:*.* . :.* : .:****:**:: :**:* .**:**: * *****. * :**. : * *..:.: *.* * ** **:***:*.**:.*: :** ** :** *::*.**:**:* **:. ***:.*.*.: ***** :*:* *:*:.********:*:*** * ***.*:**.. * .* *****. ** *.***..*.*:**************:..:", "identical_positions": 223, "similar_positions": 119, "identity": "51.26%" }, { "cls_id": "homologset.agr.RGD:1309268", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "G3V660-1", "uniprot_id": "G3V660_RAT", "id": "G3V660-1", "name": "28S rRNA (cytosine-C(5))-methyltransferase", "aln": "-----------MGLYATAAAVLAGVESRQGSLKGLVYSSNFQNLKQLYALVCETQRYSAVLDAVIASAGLLRAEKKLR------PHLAKVLVYELLLGK--GFRGGGGRWKALLGRHQARLKAELARLKVHRGVSRNEDLLQE--RPGQAHQVPRFVRVNTLKTCPEDAIDYFKRQGFSYQGR------ASSLEDLRTLKGQHFLLDPLLPELLVFPAQTD--LHEHPLYRAGHLILQDKASCLPAMLLSPPPGSHVIDACAAPGNKTSYIAALLK------NQGKIFAFDQDAKRLAAMATLLARAGVSCCEVAEKDFLTVSPSDQRYGQVQYILLDPSCSGSGMLSRQLEEHGEGTPSK-----------------------ERLQALAGFQQRALCHAL-RFPSLQRLVYSTCSLCQEENEDVVQEALQ---QNSGTFRLAP---VLPTWPHRG-LSTFPGS-------------EHCLRASPETTLTGGFFIAVFERAEVVPSPAPQTSAVVPEPLSKAPKRKRRR----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K4F6-1", "uniprot_id": "NSUN5_MOUSE", "id": "Q8K4F6-1", "name": "28S rRNA (cytosine-C(5))-methyltransferase", "aln": "-----------MGLYAAAAAVLAGVESRQGSLKGLVYSSNFQNLKQLYALVCETQRYSAVLDAVIASAGLLRAEKKLR------PHLAKVLVYELLLGK--GFRGGGGRWKALLGRHQARLKAELARLKVHRGVSRNEDLLQESSRPGQAYQVPRFVRVNTLKTRPEDAIDYFKRQGFSYQGR------ASSLEDLRALKGQHFLLDPLLPELLVFPAQTD--LHEHPLYRAGHLILQDKASCLPAMLLSPPPGSHVIDACAAPGNKTSYIAALLK------NQGKIFAFDQDAKRLAAMATLVARAGVSCCELAEKDFLTVSPSDQRYSQVQYILLDPSCSGSGMLSRQLEEHGEGTPSK-----------------------ERLQALAGFQQRALCHAL-RFPSLQRLVYSTCSLCQEENEDVVQEALQ---HNSGTFRLAP---VLPTWPHRG-LSTFPGS-------------EHCLRASPETTLTGGFFIAVFERAEVVPTPAPQTDAMDPEPLSQVPKRKRRRKAAVGASMQPST----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96P11-1", "uniprot_id": "NSUN5_HUMAN", "id": "Q96P11-1", "name": "28S rRNA (cytosine-C(5))-methyltransferase", "aln": "-----------MGLYAAAAGVLAGVESRQGSIKGLVYSSNFQNVKQLYALVCETQRYSAVLDAVIASAGLLRAEKKLR------PHLAKVLVYELLLGK--GFRGGGGRWKALLGRHQARLKAELARLKVHRGVSRNEDLLEVGSRPGPASQLPRFVRVNTLKTCSDDVVDYFKRQGFSYQGR------ASSLDDLRALKGKHFLLDPLMPELLVFPAQTD--LHEHPLYRAGHLILQDRASCLPAMLLDPPPGSHVIDACAAPGNKTSHLAALLK------NQGKIFAFDLDAKRLASMATLLARAGVSCCELAEEDFLAVSPSDPRYHEVHYILLDPSCSGSGMPSRQLEEPGAGTPSP-----------------------VRLHALAGFQQRALCHAL-TFPSLQRLVYSTCSLCQEENEDVVRDALQ---QNPGAFRLAP---ALPAWPHRG-LSTFPGA-------------EHCLRASPETTLSSGFFVAVIERVEVPR----------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q63ZY6-1", "uniprot_id": "NSN5C_HUMAN", "id": "Q63ZY6-1", "name": "Putative methyltransferase NSUN5C", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPELLVFPAQTD--LHEHPLYRAGHLILQDRASCLPAMLLDPRQAPMSWMPVPPQAIKTSHLAALLK------NQGKIFAFDLDARRLASMATLLAWAGVSCCELAEEDFLAVSPLDPRYREVHYVLLDPSCSGSGMPSRQLEEPGAGTPSP-----------------------VRLHALAGFQQRALCHAL-TFPSLQRLVYSMCSLCQEENEDMVQDALQ---QNPGAFRLAP---ALPARPHRG-LSTFPGA-------------EHCLRASPKTTLSGGFFVAVIERVEMPTSASQAKASAPERTPSPAPKRKKRAKSCSRCLHTALHIAEAPGSLLPGGKGRCLSSPWKTLGPHRRQQFAF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3BD27-1", "uniprot_id": "A0A8M3BD27_DANRE", "id": "A0A8M3BD27-1", "name": "", "aln": "-----------MALYLKAAEILEKVEQKRGAVKTLVYDSKFPNIKQLFALVCETQKYSSVLQEIINSTKLLK-ETKLR------IHLAKVLVYDLLIGH--GVKCGG-AWKTTMLKHRARLQAALARIKIKRKVSRNQDLLPSSIQQTQNDVIPRYVRVNTLKTSLEDVIDYLKREGFSYQGT------PGRLEDLDRLSGKMFLCDLHLKDLLVFSGKTD--FHDHFLYKAGHIILQGKASCLPAFLLNPPVGSHVIDACAAPGNKTSHLAAIMK------NKGKLFAFDLDAKRLSTMSTLLLRAGVTCHKLANQDFLKVDPQNSEYKEVKYILLDPSCSGSGMVCLRDELP--ETQED-----------------------GRLQALAAFQLHCLNHAL-QFPQLERIVYSTCSIHSQENEEVVTACLQ---RNPG-FRLVH---LLPDWPERG-HEPLT----------------QCLRASTAKTRTHGFFVAMLERRPAQSDKETPPLNTPLSSASQEKQDKPQSNPSDEEQENMETSNEQPANPSSKKKRK------RNRKKHKKQES--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VDZ4-1", "uniprot_id": "NSUN5_DROME", "id": "Q9VDZ4-1", "name": "28S rRNA (cytosine-C(5))-methyltransferase", "aln": "-MSKKPHSIKVPTQYRATAKILKAALEQQKCIKTLIFAEKHARTRSLHTVLKKFSENRVALEKAIEETGLLRDNPSFD------PSLAKILVTELLFGR--KELNGESKPVQTVRSYKDRLLNSIRDFGVQRKEPN-----------------PRYVRINTNLYSLAEALDYLHKSDWRRKELPADASYADFLTAIKSLAENEFMTDLHVEGVLIFPAKWSNYWVRHPLVHSKRFILQNKATCLAAELLAPPSGATVLDMCAAPGMKTVHICNVMQ------NKGCIYSVEQDHVRYNTLCEITKDAGCDIVKPILGDALNLTP--ERFPDVEYILVDPSCSGSGMQNR--MTVCDEPKED-----------------------KRLQKLQGLQIKILSHAMGAFPNVKRIAYCTCSLWKEENEQVVQRCLQ---LNPSFKLLSCKKALRNKWHNVG-DKDYPNIG------------KNVLYCQPDSDLTDGIFLALFEKRREGEKD--------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53972-1", "uniprot_id": "RCM1_YEAST", "id": "P53972-1", "name": "25S rRNA (cytosine(2278)-C(5))-methyltransferase", "aln": "MNFYRDATWVLEDIEKEAAKERISGSMQTLVLKSCKRYKLKSNPKHIYAVLDSCWKYKPYLEKVMKKAHILEDIPKKKGKPLFSRLTLLLLCHDLLLSKQKRIQMGKHPIKDYVLKFKSPLHSEMVKLKLKLKVRELSELVLS-EDISNDLPPVRWIRINPLKCHPNGETEPVLAELRKKFTL--------KVDKWSELVPGSIYYDEFIPNLFGIHPSDK--ITAHELYKHGKIIIQDRASCFPAHILNPGPSDIVIDSCSAPGNKTTHTASYIYPEPPKDNNTRIYAFEKDPERAKVLQKMIKIAGCSPNISVNVGDFTKLATPEKYKDVTCFIVDPSCSGSGIFGRKFFDSFNRRKIDDKDDDGGIVPDEQEEFIAKEELQTRLAKLSSFQFQMVKHAM-SFPAAKKIVYSTCSIHAEENERVVIDLLLDKSVREWGWKVAPKREVIPSWPRRGKVEEFEEVFRDGVTYDPQQLAEGCIRALPKSDGGIGFFAVCFERD--------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: : . . * * : ::*:*.:*:*:.* :* * . .. . ** : . : *: :::.: * * : : ** . : . .: :* .::********: ** * .:* : : **: ** :::.*. **: :*** :* * . : . * . : . . . *:* . :*: ", "identical_positions": 45, "similar_positions": 66, "identity": "7.81%" }, { "cls_id": "homologset.agr.RGD:1309269", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8C850-1", "uniprot_id": "SCAR3_MOUSE", "id": "Q8C850-1", "name": "Scavenger receptor class A member 3", "aln": "MKVRSAGSDRDVLCVTEEDLAGEDEDMPSFPCTQEGRAGPRCNRCQKNLSLHTSVRILYLFLTLLLVAVAVLASLVFRKVDSLSEDISLAQSIYNKKLVSMQENLQGLDPKALINCSFCREAEQLGQEIRKVQEELEGLQKMLLAQEVQLDQTSQTHELLSTRSSQISQEMGSCSFSIHQVNQSLGLFLAQVRGWQATTAGMDITLKDLTQECYDVKAAVHQINFTVGQTAEWIHGIQRKTDEETLTLQKIVTDWQNYTRLFGGLRTTSAKTGEIVKTIQTTLGASSQRISQNSESMHDLVLQVMGLQLQLDNISSFLDDHEENMHDLQYHTRYAQNRTVERFESLEGRMASHEIEIGTIFTNINATDNHVHSMLKYLDDVRLSCTLGFHTHAEELYYLNKSVSLMLGTTDLLRERFSLLSARLDFNVRNLSMIMEEMKAVDTHHGEILRNVTVIRGVPGPPGPRGLKGDTGVKGPVGSRGPKGDPGNLGPPGPQGPQGQPGEPGPVGERGPAGPRGFPGLKGSKGSFGTGGPRGQPGPKGDVGPLGPEGPPGSPGPSGPQGKPGISGKTGSPGQRGATGPKGEPGIQGPPGLPGPPGPPGNQSPY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZPA7-1", "uniprot_id": "D3ZPA7_RAT", "id": "D3ZPA7-1", "name": "", "aln": "MKVRSAGSDRDVLCVTEEDLAGEDEDMSSFPCSQEGRAGPRCNRCQKNLSLHTSVRILYLFLALLLVAVAVLASLVFRKVDSLSEDISLAQSIYNKKLVSMQENLQGLDPKALINCSFCREAEQLGQEIRKLQEELEGLQKMLLAQEVQLDQTSQAHELLSTTSSQISQEMGTCSFSIHQVNQSLGLFLAQVRGWQATTAGMDISLKDLTQECYDVKAAVHQINFTVGQTAEWIHGIQRKTDEETLTLQKIVTDWQNYTRLFGGLRSTSAKTGEIVKTIQATLGASSQRISQNSESMHDLVLQVMGLQLQLDNISSFLDDHEENMHDLQYHTRYAQNRTVERFESLEGRMASHEIEIGTIFTNINATDNHVHSMLKYLDDVRLSCTLGFHTHAEELYYLNKSVSLMLGTTDLLRERFSLLSARLDFNVRNLSMIMEEMKAVDTHHGEILRNVTIIRGVPGPPGPRGFKGDTGMKGPVGNKGPKGDPGSLGPPGPQGPQGQPGEPGPVGERGPAGPRGFPGLKGSKGSFGTGGPRGQPGPKGDVGPPGPEGPPGSQGPSGPQGKPGISGKAGSPGQRGATGPKGEPGIQGPPGLPGPPGPPGNQSPY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6AZY7-1", "uniprot_id": "SCAR3_HUMAN", "id": "Q6AZY7-1", "name": "Scavenger receptor class A member 3", "aln": "MKVRSAGGDGDALCVTEEDLAGDDEDMPTFPCTQKGRPGPRCSRCQKNLSLHTSVRILYLFLALLLVAVAVLASLVFRKVDSLSEDISLTQSIYDKKLVLMQKNLQGLDPKALNNCSFCHEAGQLGPEIRKLQEELEGIQKLLLAQEVQLDQTLQAQEVLSTTSRQISQEMGSCSFSIHQVNQSLGLFLAQVRGWQATTAGLDLSLKDLTQECYDVKAAVHQINFTVGQTSEWIHGIQRKTDEETLTLQKIVTDWQNYTRLFSGLRTTSTKTGEAVKNIQATLGASSQRISQNSESMHDLVLQVMGLQLQLDNISSFLDDHEENMHDLQYHTHYAQNRTVERFESLEGRMASHEIEIGTIFTNINATDNHVHSMLKYLDDVRLSCTLGFHTHAEELYYLNKSVSIMLGTTDLLRERFSLLSARLDLNVRNLSMIVEEMKAVDTQHGEILRNVTILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSFY", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*******.* *.**********:****.:***:*:**.****.*******************:**************************:****:**** **:********** *****:** *** ****:******:**:*********** *::*:*** * *******:****************************:*::*************************:*******************************.***:**:**** **.**:***************************************************:***********************************************************************:********************:********:********:*********::**.********:*** *:*****.:*******.*** ***********.********.*****************************:** ******** ***********:**:******** **********************.** *", "identical_positions": 542, "similar_positions": 49, "identity": "89.44%" }, { "cls_id": "homologset.agr.RGD:1309270", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "F1M2B7-1", "uniprot_id": "F1M2B7_RAT", "id": "F1M2B7-1", "name": "", "aln": "METSAQAPALEKKEAKSGLLEDSSFPDPGKKACPLAVAAPAA-AVAAQGVPQQLLPSFHVPLPIDMRHQEGRYHYDPHPVHGVHGPPTLSGSPVISDISLIRLSPHPAGPGESPFSAHHPYMNPHMEHYLRSVHSSPTLSMISAARGLSPADVAHEHLKERGLFSLAAPGTNPSDYYHQMTLMASHPTPYGDILMQSGGAASAPHLHDYLN---PVDASRFSSPRVTPRLSRKRALSISPLSDASLDLQRMIRTSPNSLVAYINNSRSSSAASGSYGHLSAGALSPAFTFPHP----------------INPVAYQQILSQQRGLGSAFGHTPPLIQPSPTFLAQQPMTLTSIT-VPTQLGSNSSNCISDANQNKQNSESAVSSTVNPITIHKRSKVKTEAEGLRPASPLGLTQ------------------------EQLADLKEDLDRDDCKQEAEVVIY-------ETNCHWADCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYICKIPGCTKRYTDPSSLRKHVKTVHGPDAHVTKKQRNDVHLRAPLLKENGDNEAGAEPGGRGPEESVEASSTSHTAEDCLHIKAIKTESSGLCQSSPGAQSSCSSEPSPLGSVPNNDSGVEMPGTGPGSLGDLTALDDTSPGADTSALAVPSTGGLQLRKHMTTMHRFEQLKREKLKSLKDSCSWAGPAPHTRNTKLPPLPVNGSVLENFNNTGGCGPAGLLPNQRLPEL--TEVTMLSQLQERRDSSTSTMSSAYTVSRRSSGISPYFSSRRSSEASPLGGIRPHNASSADSYDPISTDASRRSSEASQCSGGGPGLLNLTPAQQYSLRAKYAAATGGPPPTPLPGLDRVSLRTRLALLDAPERALPGACPQPLGPRRGSDGPTYNHGH--GYVGAAPALPHEGPNGSTRRASDPVRRPDPLVLPRVQRFHSIHNMNPGPLPPCTDRRGLHLQSHPSVDGSLTRHAYSPRPPSINENVVMEAVAAGVEGAGLESDLGLVEDDLVLPDDVVQYIKAHTGGALDDSTRQVYPTEGTGFPENSKLPSPGLQGHRRLAAADSNMSPSAPGLGGCQLSYSPSSSLNKSNMPVQWNEVSSGTVDALPTQVKPPSFPQSN--LVQQKPAFAHYPGYSPQALQSGSGGLDSTQPHLQLR-GAPS--ASRGSYTQQPRLPATGSQCLGVTAAMSPQANYSQTHHQLSPNVVSGSLNQFAPSCSNMAAKPSHLGLPQQMEVVPNATIISGHQRELGIASSSLAAVSQPHPVLGYPQQ----------DGYQQVSGLPSSHQPSFMESQQ------NTGFGLMQPRPPLEPNTASRHRGVRSGQQQQQLYARTAGQAVVTS-ANQETAEAMPKGTAGTVVSLTPQPS-QDTGRSQDQNTLYYYGQIHMYEQNGG------CPAMQPQPPQPQGCSDNIQPEPLPSPGVNQVSSTVDSQLLEPPQIDFDAIMDDGDHSSLFSGALSPSLLHNLSQNSSRLTTPRNSLTLPSIPVGISNMAVGDMSSMLTSLAEENKFLNMMT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q0VGT2-1", "uniprot_id": "GLI2_MOUSE", "id": "Q0VGT2-1", "name": "Transcription activator GLI2", "aln": "METSAPAPALEKKEAKSGLLEDSSFPDPGKKACPLAVAA----AVAAHGVPQQLLPAFHAPLPIDMRHQEGRYHYDPHSVHSVHGPPTLSGSPVISDISLIRLSPHPAGPGESPFSAHHPYVNPHMEHYLRSVHSSPTLSMISAARGLSPADVAHEHLKERGLFSLAAPGTNPSDYYHQMTLMASHPTPYGDLLMQSGGAASAPHLHDYLN---PVDASRFSSPRVTPRLSRKRALSISPLSDASLDLQRMIRTSPNSLVAYINNSRSSSAASGSYGHLSAGALSPAFTFPHP----------------INPVAYQQILSQQRGLGSAFGHTPPLIQPSPTFLAQQPMTLTSISTMPTQLSSSSSNCLNDANQNKQNSESAVSSTVNPITIHKRSKVKTEAEGLRPASPLGLTQ------------------------EQLADLKEDLDRDDCKQEAEVVIY-------ETNCHWADCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYICKIPGCTKRYTDPSSLRKHVKTVHGPDAHVTKKQRNDVHVRAPLLKENGDNEASAEPGGRGPEESVEASSTSHTVEDCLHIKAIKTESSGLCQSSPGAQSSCSSEPSPLGSAPNNDSGMEMPGTGPGSLGDLTALADTCPGADTSALAAPSTGGLQLRKHMSTVHRFEQLKREKLKSLKDSCSWAGPAPHTRNTKLPPLPVNGSVLENFNNTGGGGPAGLLPSQRLPEL--TEVTMLSQLQERRDSSTSTMSSAYTVSRRSSGISPYFSSRRSSEASPLGGLRPHNASSADSYDPISTDASRRSSEASQCSGGGPGLLNLTPAQQYNLRAKYAAATGGPPPTPLPGLDRVSLRTRLALLDAPERALPGACPHPLGPRRGSDGPTYSHGHGHGYAGAAPAFPHEGPNSSTRRASDPVRRPDPLILPRVQRFHSTHNMNPGSLPPCADRRGLHVQSHPSVDSNLTRNAYSPRPPSINENVVMEAVAAGVDGPGLECDLGLVEDELVLPDDVVQYIKAHTGGTLDDGIRQGYPTEGTGFPENSKLPSPGLQGHRRLAAADSNMGPSAPGLGGCQLSYSPSSNLNKSNMPVQWNEVSSGTVDALPTQVKPPPFPHSNLAVVQQKPAFGQYPGYNPQSVQSSSGGLDSTQPHLQLR-GAPS--ASRGSYTQQPRQPAAGSQCLGMSAAMSPQASYSQAHPQLSPNIVSGSLNQFSPSCSNMAAKPSHLGLPQQMEVVPNATIMNGHQREHGVPNSSLAAVSQPHPVLSYPQQ----------DSYQQGSNLLSSHQPGFMESQQ------NAGFGLMQPRPPLEPNTASRHRGVRSGQQQ--LYARTTGQAMVTS-ANQETAEAMPKGPAGTMVSLAPQPS-QDTGRAQDQNTLYYYGQIHMYEQNGG------CPAVQPQPPQPQACSDSIQPEPLPSPGVNQVSSTVDSQLLEPPQIDFDAIMDDGDHSSLFSGALSPTLLHNLSQNSSRLTTPRNSLTLPSIPAGISNMAVGDMSSMLTSLAEESKFLNMMT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P10070-5", "uniprot_id": "GLI2_HUMAN", "id": "P10070-5", "name": "Transcription activator GLI2", "aln": "METSASATASEKQEAKSGILEAAGFPDPGKKASPLVVAAAAAAAVAAQGVPQHLLPPFHAPLPIDMRHQEGRYHYEPHSVHGVHGPPALSGSPVISDISLIRLSPHPAGPGESPFNAPHPYVNPHMEHYLRSVHSSPTLSMISAARGLSPADVAQEHLKERGLFGLPAPGTTPSDYYHQMTLVAGHPAPYGDLLMQSGGAASAPHLHDYLN---PVDVSRFSSPRVTPRLSRKRALSISPLSDASLDLQRMIRTSPNSLVAYINNSRSSSAASGSYGHLSAGALSPAFTFPHP----------------INPVAYQQILSQQRGLGSAFGHTPPLIQPSPTFLAQQPMALTSINATPTQLSS-SSNCLSDTNQNKQSSESAVSSTVNPVAIHKRSKVKTEPEGLRPASPLALTQGQVSGHGSCGCALPLSQ-------EQLADLKEDLDRDDCKQEAEVVIY-------ETNCHWEDCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYICKIPGCTKRYTDPSSLRKHVKTVHGPDAHVTKKQRNDVHLRTPLLKENGDSEAGTEPGG---PESTEASSTSQAVEDCLHVRAIKTESSGLCQSSPGAQSSCSSEPSPLGSAPNNDSGVEMPGTGPGSLGDLTALDDTPPGADTSALAAPSAGGLQLRKHMTTMHRFEQLKKEKLKSLKDSCSWAGPTPHTRNTKLPPLPGSGSILENFSGSGGGGPAGLLPNPRLSELSASEVTMLSQLQERRDSSTSTVSSAYTVSRRSSGISPYFSSRRSSEASPLGAGRPHNASSADSYDPISTDASRRSSEASQCSGG-SGLLNLTPAQQYSLRAKYAAATGGPPPTPLPGLERMSLRTRLALLDAPERTLPAGCPRPLGPRRGSDGPTYGHGH----AGAAPAFPHEAPGGGARRASDPVRRPDALSLPRVQRFHSTHNVNPGPLPPCADRRGLRLQSHPSTDGGLARGAYSPRPPSISENVAMEAVAAGVDGAGPEADLGLPEDDLVLPDDVVQYIKAHASGALDEGTGQVYPTESTGFSDNPRLPSPGLHGQRRMVAADSNVGPSAPMLGGCQLGFGAPSSLNKNNMPVQWNEVSSGTVDALASQVKPPPFPQGNLAVVQQKPAFGQYPGYSPQGLQASPGGLDSTQPHLQPRSGAPSQGIPRVNYMQQLRQPVAGSQCPGMTTTMSPHACYGQVHPQLSPSTISGALNQFPQSCSNMPAKPGHLGHPQQTEVAPDPTTMGNRHRELGVPDSALAGVPPPHPVQSYPQQSHHLAASMSQEGYHQVPSLLPARQPGFMEPQTGPMGVATAGFGLVQPRPPLEPSPTGRHRGVRAVQQQ-LAYARATGHAMAAMPSSQETAEAVPKGAMGNMGSVPPQPPPQDAGGAPDHSMLYYYGQIHMYEQDGGLENLGSCQVMRSQPPQPQACQDSIQPQPLPSPGVNQVSSTVDSQLLEAPQIDFDAIMDDGDHSSLFSGALSPSLLHSLSQNSSRLTTPRNSLTLPSIPAGISNMAVGDMSSMLTSLAEESKFLNMMT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P19538-1", "uniprot_id": "CI_DROME", "id": "P19538-1", "name": "Transcriptional activator cubitus interruptus", "aln": "MDAYALPTYFPLAYSELQFLASRRAAAVAAAATVLPGSP-----CINQHHPTDVSSSVTVPSIIPTGG-------TSDSIKTSIQP------QICNENTLLGNAGHQHNHQPQHVHNINVTGQPHDFHPAYRIPG-YMEQLYSLQRTNSASSFHDPYVNCASAFHLAGLGLGSADFLGSRGLSSLGELHNAAVAAAAAGSLASTDFHFSVDGNRRLGSPRPPGGSIRASISRKRALSSSPYSDS-FDINSMIRFSPNSLATIMNGSRGSSAASGSYGHISATALNPMSHVHSTRLQQIQAHLLRASAGLLNPMTPQQVAASGFSIGHMPTSASLRVNDVHPNLSDSHIQITTSPTVTKDVSQVPAAAFSLKNLDDAREKKGPFKDVVPEQPSSTSGGVAQVEADSASSQLSDRCYNNVVNNITGIPGDVKVNSRLDEYINCGSISIPSNEYDCANADTTDIKDEPGDFIETNCHWRSCRIEFITQDELVKHINNDHIQTNKKAFVCRWEDCTRGEKPFKAQYMLVVHMRRHTGEKPHKCTFEGCFKAYSRLENLKTHLRSHTGEKPYTCEYPGCSKAFSNASDRAKHQNRTHSNEKPYICKAPGCTKRYTDPSSLRKHVKTVHGAEFYANKKHKG-----LPLNDAN---------------------------------SRLQQNNSRHNLQEHNIDSSPCSEDSHLG---------KMLGTSSPSIKSESDISSSNHHLVNGVRASDSLLTYSPDDLAENLNLDDGWNCDDDVDVADLPIVLRAMVNIGNGNASASTIGGSVLARQRFRGRLQTKGINS---------STIMLCNIPESNRTFGISELNQRITELKMEPGTDAEIKIPK----------LPNTTIGGYTEDPLQNQTSFRNTVS-----------NKQGTVSGSIQGQFRRDSQNSTASTYYG----SMQSRRSSQSSQVSSIPTMRPNPS-------------------CNSTASFYDPISPGCSRRSSQMSNGANCNSFTSTSGLPVLNKESNKSLNACINKPNIGVQGVGIYNSSLP-------PPPSSHLIATNLKRLQRKDSEYHN---FTSGRFSVPSYMHSLHIKNNKPVGENEFDKAIASNAR--RQTDPVPNINLDPLTNISRFSTTPHSFDINVG---KTNNIASSINKDNLRKDLFTVSIKADMAMTSDQHPN--ERINLDEVEELILPDEMLQYLN-LVKDDTNHLEKEHQAVPVG--------SNVSETIASNHYREQSNIYYTNKQILTPPSNVDIQPNTTKFTVQDKFAMTAVGGSFSQRELSTLAVPNEHGHAKCESFHHQSQKYMNTDIGSKQQSALPSAHQRQTEK----------SNYNQIIDSSMTSLP---------------ELNVDSIYPRNETENIFKVHGDHDNEIQCGIISQSQ---------------------------MSPSTNLNNDGQ---------FSTVNMQPITTS----------KLFPPEPQKIVCDTQASNTSVMHLDTYQRTLEYVQSCQNWMETNNTSTN-QIQSLPGMPVNNTLFPDVSSSTHPYHG--------------TNMVINDMTTSLTSLLEENRYLQMMQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:: * .. :: :* . . * * :. : * .: ... .* * ...:: * : .: :*: : * . . . : :** * : . .: * * *.:.. . ::: . * *.. * .:*: . * : . : :.*: ::..:* :: :. .* .. : . :******* ** **: :*:: *** *****.: :*.**.**********:** **.* . . :**:: **: :. .:* :. :: . *::. : :*: ..::.. .: .:. * :. .:.. . * * . * :: *. .:* *. : ..:. :. ** : . * ****** .* *: **::**:****:**: :** *****: *** :***************************** **********************.**: **.************************** **********************.: :..**::. ** . * :: :.* .. . :** .** * ** :* **.. *: . : : .: ... * * . . .:: : : :. .: * . : * : .. . .**:* . * . *: . : : : . :..* . * :.. * : ..* .. :. : *:.: .. : **:..::* *.: : * : . .::.:: : ....:. * *:::* : .: ::* *.* .::.:: . . . :**:*: . .: :. .. : :: . .* .* :: .: :*. :..*. **. .. :. : ... . : .. : :*. : . : . :: : .::. :. :*. .*. .: .:. . :* . .*.:**.*: : ** : *:.:: :* : * *:: . * :: ... *:. : : .. . . *: . : . . : : : : :.. : . . * : . *. *:: . : :: . .: . * . .:: ..*:* . : * :.: . * *.. : :* : : * ::: :.*.. :: * :. ::* . : **:** . *.. . :: . *:: :: : : : .** . .:. :*: .:*..: :**.:.**:: **** **.::*:** ", "identical_positions": 316, "similar_positions": 467, "identity": "19.4%" }, { "cls_id": "homologset.agr.RGD:1309271", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CFS6-1", "uniprot_id": "KCNV2_MOUSE", "id": "Q8CFS6-1", "name": "Potassium voltage-gated channel subfamily V member 2", "aln": "MLKQSNERRWSLSYKPWSTPETEDVPNTGSNQHRRSICSLGARTGSQASIAPQWTEGNYNYYIEEDEDCGEEGEDWKDDLAEENQKA-ECLTSLLDGHNDTPAQMSTLKVNVGGHSYLLECCELANYPKTRLGRLATSTTRRGQLGLCDDYEAQTDEYFFDRDPAVFQLIYNFYTSGVLLVRDELCPRSFLEELGYWGVRLKYTPRCCRICFEERRDELSEQLKIQRELRAQAQAEEAEELFRDMRFYGPQRQRLWNLMEKPFSSVAAKAMGVATNLFVLISVVALALNTVEEMQHQAEQGTGGGDPRPILEHVEMLCVAFFTLEFLLRLASTPNLQRFARSALNLVDLVAILPFYLQLLLECFTSEDQRHNKDSPREHDLETVGRVGKVGQVLRIMRLMRIFRILKLARHSTGLRAFGFTLRQCYQQVGCLMLFITMGIFSFSAAVYSVEHDVPGTNFTSILHAWWWAAVSISTVGYGDMYPETHLGRLFAFLCIAFGIILNGMPISILYNKFSDYYSKLKAYEYTAIRRERGKVNFMQRATKKMAECLSESHAQSTTRQEN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZZR6-1", "uniprot_id": "D3ZZR6_RAT", "id": "D3ZZR6-1", "name": "Potassium voltage-gated channel subfamily V member 2", "aln": "MLKQSTERRWSLSYKLWNTSETEDVPNTGSNQHRKSICSMGARTGSQASIAPQWTEGNYNYYIEEDEDCGEE-EDWKDDLAEENQKP-EGPPAPLDGHTDTPTQLSTLKVNVGGHSYQLECCELANYPKTRLGRLVTSTSRNCQLGLCDDYEAKTDEYFFDRDPAVFQLIYNFYTSGVLLVRDELCPRSFLEELGYWGVRLKYTPRCCRICFEERRDELSEQLKIQRELRAQAQAEEAEELFRDMRFYGPQRQRLWNLMEKPFSSVAAKAMGVASNLFVLISVVALALNTVEEMQHQAEQGTGGGDPRPILEHVEMLCVAFFTLEFLLRLASTPNLRRFARSALNLVDLVAILPFYLQLLLECFTSEDQRHGKGSPREHDLETVGRVGKVGQVLRIMRLMRIFRILKLARHSTGLRAFGFTLRQCYQQVGCLMLFITMGIFSFSAAVYSVEHDVPGTNFTSILHAWWWAAVSISTVGYGDMYPETHLGRLFAFLCIAFGIILNGMPISILYNKFSDYYSKLKAYEYTAIRRERGKVNFMQRATKKMAECLSGSNAQSATRQEN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8TDN2-1", "uniprot_id": "KCNV2_HUMAN", "id": "Q8TDN2-1", "name": "Potassium voltage-gated channel subfamily V member 2", "aln": "MLKQS-ERRRSWSYRPWNTTE-----NEGS-QHRRSICSLGARSGSQASIH-GWTEGNYNYYIEEDED-GEEEDQWKDDLAEEDQQAGEVTTAKPEGPSDPPALLSTLNVNVGGHSYQLDYCELAGFPKTRLGRLATSTSRSRQLSLCDDYEEQTDEYFFDRDPAVFQLVYNFYLSGVLLVLDGLCPRRFLEELGYWGVRLKYTPRCCRICFEERRDELSERLKIQHELRAQAQVEEAEELFRDMRFYGPQRRRLWNLMEKPFSSVAAKAIGVASSTFVLVSVVALALNTVEEMQQHSGQGEGGPDLRPILEHVEMLCMGFFTLEYLLRLASTPDLRRFARSALNLVDLVAILPLYLQLLLECFTGEGHQRG---------QTVGSVGKVGQVLRVMRLMRIFRILKLARHSTGLRAFGFTLRQCYQQVGCLLLFIAMGIFTFSAAVYSVEHDVPSTNFTTIPHSWWWAAVSISTVGYGDMYPETHLGRFFAFLCIAFGIILNGMPISILYNKFSDYYSKLKAYEYTTIRRERGEVNFMQRARKKIAECLLGSNPQLTPRQEN", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***** *** * **: *.*.* * ** ***:****:***:****** *************** *** ::********:*:. * .: :* .*.*: :***:******** *: ****.:********.***:* **.****** :***************:**** ****** * **** ********************************:****:*******.*****************:*****************:***:. ***:**************::: ** ** * ***********:.*****:********:*:*****************:**********.*.:::. :*** *********:************************************:***:****:*************.****:* *:************************:*************************************:******:******* **:**** *:.* :.****", "identical_positions": 445, "similar_positions": 66, "identity": "79.04%" }, { "cls_id": "homologset.agr.RGD:1309272", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4ADE6-1", "uniprot_id": "D4ADE6_RAT", "id": "D4ADE6-1", "name": "Sal-like protein 2", "aln": "MSRRKQRRPQQLISDCEGPS-ASENGDASEEDHPQVCAKCCAQFSDPTEFLAHQNACCTDPPVMVIIGGQENPSNSSVSSVP------------RPEGHSRPQVMDTEHSNLPDSGSSGPPDPAWGSERRGEESSGQFLVAGTGTAAGGGGGLILASPKLGATPLPPESTPAPPPPPPPPPPPGVGSGHLNIPLILEELRVLQQRQIHQMQMTEQICRQVLLLGSLGQTVGAPASPSELPGTGTASSTKPLLPLFSPIKPAQTGKTLASSSSSSSSS-GAEPPKQAFFHLYHPLGSQHPFSVGGVGRSHKPTPAPSPALPGSTDQLIASPHLAFPGTTGLLAAQCLGAARGLEAAASPGLLKPKNGSGELGYGEVISSLEKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREKYPHVQMNPHP--VPEHLDYVITSSG--------------------------LPYGMSVPPEKAEEEAATPGGGVERKPLVASTTALSATESLTLLSTGTSTAVAPGLPTFNKFVLMKAVE--PKSKVDENTPPGSEGSAISGVADSGSATRMQLS-KLVTSLPSWALLTNHLKSTG----SFPFPYVLEPLGASP-----------SETSKLQQLVEKIDRQ---------------------------------GAVAVASTASGAPTTSAPAPSSSAS-GPNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKTSPA-ARAQNSCPICQKKFTNAVTLQQHVRMHLGGQIP---------------NGGSTLPEGGGVAQENSSEQSTASGPGSFPQPQAQQPSAEEEISEEEEE-DEEEEE----------DVTDEDSLAGRGSESGGEKAISVRGDSEEVSG----AEEEAATSGAAPTNGKE-------VDNNEK-------ATQQALPPPP----------------------------------------------------------------------------------PPPDNLDRPQPMEQGPSDVSGGMEEEAKLEGTSSP--MAALPQEGEGTSTPSVEELNLPEAMKKEPGESS-----------------------------------------------------SRKACEVCGQSFPTQTALEEHQKTHP---KDGPLFTCVFCRQGFLDRATLKKHMLLAHHQVPPFAP---------------------------------------------------------------HGP----------------------QNIATLSLVPGCSSSIPSPGLSPFPRKDDPAIP-----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QX96-1", "uniprot_id": "SALL2_MOUSE", "id": "Q9QX96-1", "name": "Sal-like protein 2", "aln": "MSRRKQRRPQQLISDCEGPS-ASENGDASEEDHPQVCAKCCAQFSDPTEFLAHQNSCCTDPPVMVIIGGQENPSNSSASSAP------------RPEGHSRSQVMDTEHSNPPDSGSSGAPDPTWGPERRGEESSGQFLVAATGTAAGGGGGLILASPKLGATPLPPESTPAPPPPPPPPPPPGVGSGHLNIPLILEELRVLQQRQIHQMQMTEQICRQVLLLGSLGQTVGAPASPSELPGTGAASSTKPLLPLFSPIKPAQTGKTLASSSSSSSSS-GAEPPKQAFFHLYHPLGSQHPFSVGGVGRSHKPTPAPSPALPGSTDQLIASPHLAFPGTTGLLAAQCLGAARGLEAAASPGLLKPKNGSGELGYGEVISSLEKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREKYPHVQMNPHP--VPEHLDYVITSSG--------------------------LPYGMSVPPEKAEEEAGTPGGGVERKPLVASTTALSATESLTLLSTGTSTAVAPGLPTFNKFVLMKAVE--PKSKADENTPPGSEGSAIAGVADSGSATRMQLS-KLVTSLPSWALLTNHLKSTG----SFPFPYVLEPLGASP-----------SETSKLQQLVEKIDRQ---------------------------------GAVAVASTASGAPTTSAPAPSSSAS-GPNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKTSPA-ARAQNSCPICQKKFTNAVTLQQHVRMHLGGQIP---------------NGGSALSEGGGAAQENSSEQSTASGPGSFPQPQSQQPSPEEEMSEEEEE-DEEEEE----------DVTDEDSLAGRGSESGGEKAISVRGDSEEVSG----AEEEVATSVAAPTTVKE-------MDSNEK-------APQHTLPPPP----------------------------------------------------------------------------------PPPDNLDHPQPMEQGTSDVSGAMEEEAKLEGTSSP--MAALTQEGEGTSTPLVEELNLPEAMKKDPGESS-----------------------------------------------------GRKACEVCGQSFPTQTALEEHQKTHP---KDGPLFTCVFCRQGFLDRATLKKHMLLAHHQVPPFAP---------------------------------------------------------------HGP----------------------QNIATLSLVPGCSSSIPSPGLSPFPRKDDPTMP-----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y467-1", "uniprot_id": "SALL2_HUMAN", "id": "Q9Y467-1", "name": "Sal-like protein 2", "aln": "MSRRKQRKPQQLISDCEGPS-ASENGDASEEDHPQVCAKCCAQFTDPTEFLAHQNACSTDPPVMVIIGGQENPNNSSASSEP------------RPEGHNNPQVMDTEHSNPPDSGSSVPTDPTWGPERRGEESSGHFLVAATGTAAGGGGGLILASPKLGATPLPPESTPAPPPPPPPPPPPGVGSGHLNIPLILEELRVLQQRQIHQMQMTEQICRQVLLLGSLGQTVGAPASPSELPGTGTASSTKPLLPLFSPIKPVQTSKTLASSSSSSSSSSGAETPKQAFFHLYHPLGSQHPFSAGGVGRSHKPTPAPSPALPGSTDQLIASPHLAFPSTTGLLAAQCLGAARGLEATASPGLLKPKNGSGELSYGEVMGPLEKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREKYPHVQMNPHP--VPEHLDYVITSSG--------------------------LPYGMSVPPEKAEEEAATPGGGVERKPLVASTTALSATESLTLLSTSAGTATAPGLPAFNKFVLMKAVE--PKNKADENTPPGSEGSAISGVAESSTATRMQLS-KLVTSLPSWALLTNHFKSTG----SFPFPYVLEPLGASP-----------SETSKLQQLVEKIDRQ---------------------------------GAVAVTSAASGAPTTSAPAPSSSASSGPNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKASPA-ARAQNSCPICQKKFTNAVTLQQHVRMHLGGQIP---------------NGGTALPEGGGAAQENGSEQSTVSGARSFPQQQSQQPSPEEELSEEEEEEDEEEEE----------DVTDEDSLAGRGSESGGEKAISVRGDSEEASG----AEEEVGTVAAAATAGKE-------MDSNEK-------TTQQSSLPPP----------------------------------------------------------------------------------PPPDSLDQPQPMEQGSSGVLGGKEEGGKPERSSSP--ASALTPEGEATSVTLVEELSLQEAMRKEPGESS-----------------------------------------------------SRKACEVCGQAFPSQAALEEHQKTHP---KEGPLFTCVFCRQGFLERATLKKHMLLAHHQVQPFAP---------------------------------------------------------------HGP----------------------QNIAALSLVPGCSPSITSTGLSPFPRKDDPTIP-----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4I9L7-1", "uniprot_id": "A0A0R4I9L7_DANRE", "id": "A0A0R4I9L7-1", "name": "", "aln": "MSRRKQKRPQQLVNADPGGTRLMPQEDQLQVKSPSTSLASEATSSSSSSSPTSLQDCQPPLAPRPSPGGLHAPSLPNESSSPPHWPNHIASYSTSLPNAHSSLSPDFPHPSLSSQTHSPPPGQQKSTRISSHQPHSTVTSPPMGISATTTTSSLSSSSSLGAPPHQGSPSPIHQTPSSPSEQLQVPP---TLAVLLEELRVLQQRQIHQMQITEEICRQVLRLGGMVSAPDAPQGSVEGQQRDAGSSSPPNG---------VSGASLINQAPVSKPNLSQTNGGRAPYSTTSSSTSSSSSLVTSTATVHPLSLTLG-LPPRYLNEKSANTPISHGNGLNFQTSPLPTVSISQDQLSHSSTVSTSNGSSSSSSGRQQ---------HICRFCGKVLSSDSSLQIHLRSHTGERPYQCPVCLSRFTTRGNLKAHFLRHREQNPELSLSLLPPALSEQSQSGSGSGGSQRRRKRRAEDEEPFGVKGSVGVPDSLALGFLSGPAHPSPSSLPLPPSVDLALLSTAHSLLQLNRASAAAAASVSPSVQSSSSSITSSAMTGQLKGSKQQRFDENTPPHPTLHHGSPYSQLAHLPKILFPSGPSAHHPSLALLRPPHLTSPHLPLTFPFSSYPKPQNSSPPSSSPSSSSATSDTSKLQRLAQKLEKQPLPKSTNEGQTNTQANDISTSSNAISAYRREMMAALGLNPNPSSEPTSQEIQGSAASSLVPNQCGVCLRVLSCPRALRLHQATHLGERPFPCKLCGRSFSTKGSLRAHLATHRARPANARGQNSCPLCQRKFTNAVVLQHHIRMHLGGQLPPEVNGDLQSEDAHSQIDGISLPKSLQSLPLNMSMSSAASLLDSGAILRDPTSGDTDQLMESDQDPYENTSENSPTFTLEKQDPSRENSPLDNSVALEENHYVTVHHSKSQVVNGSAHKDEDTPLSLCTRTSSQDPLFDKKWQNGASH-------HTVISGPKPS----------------------------------------------------------------------------------LSSEALDLSPALTPPSSPGLESKPDQSSEQTTLHVNGIDHVPEFKDADSHPAPENVIEHKLKADDTQESK-----------------------------------------------------MEESAVEDHKKDSEKTEVTSSEAPVAQPQRSEKPYSCTECGKEYASRSGLKGHMKIHSGSMNQVAG---------------------------------------------------------------TASSQSSGGKVAERMEESTHRKLRGEDAKNLSEESTDKLSLTEHPASTTDRTEDTA-------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VKH3-1", "uniprot_id": "Q9VKH3_DROME", "id": "Q9VKH3-1", "name": "", "aln": "MCSIFRNRIN-----YRGTGGTRSGSGERERDRDRDRDRDRDRERDRDTLLAKELDADSN---------------------------------------NNGTEPQMEAEAVPESDTERETAEERGEE---QEPENSNEALDLSLISSGGRESLPGSGHVSLEALQHTKVAVAQFAATAMAG---NHQSADLAMVQSTIFNVQRQHLMQLQLIQHLQSQLKRAEAAALGRHSHSDEEEEEPEPEPEPKKQPTNGLKEELELEQGPESEQDQESRREENSKTDKRGTEDRKAEPEGYQS--MMCDISSSLASSIITNHDPPPAPNEPNCLEMLQRRTEEVLDSASQSLHAAQMQEEYSEYASKEAQSRGEIFK-------------HRCKYCGKIFGSYSALQIHLRSHTGERPFVCNVCGSKFTTKGNLKVHYQRHTQIFPPMLLPPGVAPNVGHSGQGQVQGEQ-------------------------YPIRLPFAPPVAPVGQEQHQNQVEEPEEIRQEIPVPQAEDLSKPMVKEKEKSHSPVERVKTPKEVKTDAALPSSEKPEKEISKPVVTSSRRNGSVRKRQTSAVS--PPQEDRERDLVEHLHIAKL-------VRRSSASRESQP------------AEYSLAQMERIIDKS-------------------------------WEDLIEIDKTSETSKLQQLVDNIENKLTDPNQCIFCQKVMSCRSSLQMHIRTHTGERPFRCKICGRAFATKGNLKAHMSIHKIKPP-MRSQFKCPVCHQKFSNGIILQQHIRIHTMDDGSGGQGAPAANPGEAERLGIEDQNSNKSLGTSDTLDFSTTISDHSGQRSESSQGGDFDEFMTMDSTDDSRDNSSAATATP-HPLERERDREKERERRIPNDCSDERSHSNPDLTGGRSESGEMPAMDLSSPSSNSGRIFATGLANGAAGGGSGNGGLPMLGMPMPPNLLLMAAAREEMHALGHAHAKFPLLPFGPLGFMGLHPPPNVCNLCFKMLPSLAALESHLQSEHAKEPATGHAQRPQCSDAGSPYGAKLTLNPNLFAKKPPSSSSSSSGEKLPESSNPPFPAENPPATPIKEDPDQEQLMVEEGASAGEGSGTGATSNYPQEAGDAEQSLMKMQLHAHRFPASPLDFQQALMSAGPPTSSLDPPVNNKHFCHVCRRNFSSSSALQIHMRTHT----GDKPFQCNVCQKAFTTKGNLKVHMGTHMWTNPTSRRGRRMSLELPMRPGPNSGQGHPGSSAEQEFMQRRPELFFPYLPPFFNGLPPKPGELSPGAFPNIPPPPFANGGKYPYPPGLLGFPGFLAQHPYILERRSSSKSPTPEPAQSPALREEEGSGNIWHPLSRIKVENNQNESMGGFNEQEDHAETDATGGDNDESESRDAEK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. :.: : * . : . . : . . : ... . . . . .:. . . : : .* :. . . .... :.:: . : :*:::: *:*: :.: *: . : . * ... . .. . . : . . . . : . * :: . : : :: : : . :. .. * *::*.*::.* *:*************: * ** .:***:****.*: ** : * : : : .. . : * . *: : . : . . ... ... *: . . .. .. . *: :. . . :.* .* :: . :::. : : .. . **** .* :*:** :*::* * ***** **:***:*:*:*.*:**: *: *. *.* .**:*::**:*.: **:*:*:* .: . . .. : *:. * . . ::: :. .. .. .: . : .. : . * .: : . :. . *. * : . . . . : . . . *:: : ... .. . : . .: : . . : * * : : :. ** ** . :. *. . . . .. *. * :: : ", "identical_positions": 105, "similar_positions": 252, "identity": "7.42%" }, { "cls_id": "homologset.agr.RGD:1309273", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4ADJ8-1", "uniprot_id": "D4ADJ8_RAT", "id": "D4ADJ8-1", "name": "", "aln": "-MEGLVLLKALVTRLLFLLHSLVAVWRVTWVKEEHRYWLLALLNLLLVLETVLTLKFKRGRGYKWLSPAIFLYLINIMPSLWLLEMHHGNQYCSTQSETAAQNFSGRGD----INQTLSSHRATDGVGNILELARGFVDNLSMVCEPVWTLGLHQTLLLILIIGRWLLPIGGTITRDQLSELLLMFVGTAADILEFTTETLKENNVRNNPALVSGILVVWTWSMLQFPLDLAVQLKLVCPAS-VKARG--FLRVFLCQYSADLWAIGLSFFIQDGPFLVVRLVLMIYFKVINHMLVFFAVKNSLVMALHFYRLVALIMATRDFMQD------------------------------------------------------------------------------------------------HPESPKTEHSGPDQPSESGPS--EWEDTSPE--ALPLRISPVTSEESYPTTP---------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UP23-1", "uniprot_id": "TMM26_MOUSE", "id": "Q3UP23-1", "name": "Transmembrane protein 26", "aln": "-MEGLVLLKALVTRLLFLLHSLVAVWRVTWVKEEHRYWLLALLNLLLVLETVLTLKFKRGRGYKWLSPAIFVYLVNIMPSLWLLEMHHGNQYCSTQSERMAQNFSRRGD----VNQTLSSHRATNGMGNILELARGFVDNLSMVCEPVWTLGLHQTLLLILIIGRWLLPIGGTITRDQLSELLLMFVGTAADILEFTTETLKENNVRTNPTLVSGILVVWTWSMLQFPLDLAVQLKLVCPAS-VKARG--FLRVFLCQYSADLWAIGLSFFIQDGPFLVVRLVLMIYFKVINHMLVFFAVKNSLVMALHFYRLVALIMATRDFMRD------------------------------------------------------------------------------------------------HPESPKPEHSGPDQPSESGPS--EWEDASPE--ALPLRTSPVTSEESYPTTP---------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZUK4-1", "uniprot_id": "TMM26_HUMAN", "id": "Q6ZUK4-1", "name": "Transmembrane protein 26", "aln": "-MEGLVFLNALATRLLFLLHSLVGVWRVTEVKKEPRYWLLALLNLLLFLETALTLKFKRGRGYKWFSPAIFLYLISIVPSLWLLELHHETQYCSIQAEGTSQNTSRKED----FNQTLTSNEQTSRADDLIETAKVFVNNLSTVCEKVWTLGLHQTFLLMLIIGRWLLPIGGGITRDQLSQLLLMFVGTAADILEFTSETLEEQNVRNSPALVYAILVIWTWSMLQFPLDLAVQN-VVCPVS-VTERG--FPSLFFCQYSADLWNIGISVFIQDGPFLVVRLILMTYFKVINQMLVFFAAKNFLVVVLQLYRLVVLALAVRASLRS------------------------------------------------------------------------------------------------QSEGLKGEHGCRAQTSESGPSQRDWQNESKEGLAIPLRGSPVTSDDSHHTP----------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1Q715-1", "uniprot_id": "A0A8M1Q715_DANRE", "id": "A0A8M1Q715-1", "name": "", "aln": "-MILVKFVCAIITRSLFILVSLIGVWRVKTVKNDNMYWLLTILYLPLVVEMIITLKRRKGQDYKWFSPAILLFLISIIPSIWILELHHQENKAS---DPQCRKLDSWDN----VKSILPSNGTMG-----NATLKYLESMLTSVCANDWILALHQVLLILLILGKWLLPLGGGVTRDELSQLLLIFVGTAADILEFTSETLSDVKE-NNHQLVYIILAVWTWSMLQFPLHLAVVTSRPENTD-EPKGGDGCCNLILSRHSTDIWNIVESLFIQDGPFLVVRLIVMIYFDVFHQMLVFFAIKNFLVVVLNLYRLIVICQDFR----------------------------------------------------------------------------------------------------------------PKPPSSSSS--------------VPI------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VBE7-1", "uniprot_id": "Q9VBE7_DROME", "id": "Q9VBE7-1", "name": "Transmembrane protein 26", "aln": "MAKIISTIKAILTRIIFSAHSLLAIWQVVALKSDIIYWALCGPLLLLLLEGIFTIMIKKTQEWRWFCPSVFLYLSSIVPAIWLLELDKVARRVGNMTSTNSTVYSPSNYSIPVGNTTIFITSTNSSGVPPVATLLGQAGVTLSVTPDTWTTLIEQFLMLILIVGRWLLPKG-DLTRDQLSQLLLVYIGTAADIIEFFDS-YKDDSIAKIGFLVFLTLGIWSWSLMQFTIVLSATRGRRPRGSGSHHKEEHTDCCQNCCCGIDVWGIVLNVILQDAPFLTFRLLIIFQYKIINYMNVFFTCKNSLVIILQLYRLYVVNAEFWKNRRESRMAKSRQFQSRRKVQDADQNSIYMISNERGGDVKKKIKRAKDKDYAEQEAVYSKKKKDKKDKKKRKRKDTGYSTASSQNLYSTKASGTDKDTRRKDKKGKKSKRTCSSSPSDCDLAKKQKRKNADKNDKKKSRKIEAVVEESSSSSSSSSDSSNSTLPSYEVIDEKKARRRKHRGSSSDTSSGDSSSSSSSSSSSDSS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : *: ** :* **:.:*:* :*.: ** * * *.:* :*: :: : ::*:.*:::::* .*:*::*:**:.: . . . . . : : . . * * :.* ::::**:*:**** * :***:**:***:::******:** . .: . . ** * :*:**::**.: *:. . . . *:* * ..::**.***..**::: :.::: * ***: ** **: *::*** .: .*... ", "identical_positions": 83, "similar_positions": 101, "identity": "15.81%" }, { "cls_id": "homologset.agr.RGD:1309274", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WVS4-1", "uniprot_id": "MOK_MOUSE", "id": "Q9WVS4-1", "name": "MAPK/MAK/MRK overlapping kinase", "aln": "---------------------------------------------------------------------------------------------MKNYKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQHFESIEQVNSLREIQALRRLNPHPNILALHEVVFDRKSGSLALICELMDMNIYELIRGRRHPLSEKKIMLYMYQLCKSLDHMHRNGIFHRDVKPENILVKQDVLKLGDFGSCRSVYSKQPYTEYISTRWYRAPECLLTDGFYTYKMDLWSAGCVFYEIASLQPLFPGVNELDQISKIHDVIGTPCQKTLTKFKQSRAMSFDFPFKKGSGIPLLTANLSPQCLSLLHAMVAYDPDERIAAHQALQHPYFQVQRAAETQTLAKHRRAFCPKFSMVPESSSHNWSFSQEGRKQKQSLRHEEGHARRQGPTSLMELPKLRLSGMTKLSSCSSPALRSVLGTGANGKVPVLRPLKCAAVNKKTDTQKDIKPHLKHYHLPTINRKGGEY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7F4B1-1", "uniprot_id": "F7F4B1_RAT", "id": "F7F4B1-1", "name": "MAPK/MAK/MRK overlapping kinase", "aln": "MREQRSFSSASQPHLEHAYTPVSGKPLPPKGLAVARATGIQYGGWILTLPSQGPLRRSSSRKPPLERRRPLPQSPLFFSARGDQGLTASSAFRMKNYKAIGKIGEGTFSEVLKMQSLRDGNYYACKQMKQHFESIEQVNNLREIQALRRLNPHPNILTLHEVVFDRKSGSLALICELMDMNIYELIRGRRHPLSEKKIMHYMYQLCKSLDHMHRNGIFHRDVKPENILVKQDVLKLGDFGSCRSVYSKQPYTEYISTRWYRAPECLLTDGFYTYKMDLWSAGCVFYEIASLQPLFPGVNELDQISKIHDVIGTPCQKTLTKFKQSRAMSFDFPFKKGSGIPLLTTNLTPQCLSLLHAMVAYDPDERIAAHQALQHPYFQVQRAAETQTLAKHRRAFYPKYSMVPESSSHNWSFSKEGRKQ-QPLRQEEGRARRQGPTSLTELPKLRLSGMTKLSSCSSPALRSVLGTGANGRVPVLRPLKCAVVNKKTDTQKDIKPHLKHCHLPTINRKGGEY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UQ07-1", "uniprot_id": "MOK_HUMAN", "id": "Q9UQ07-1", "name": "MAPK/MAK/MRK overlapping kinase", "aln": "---------------------------------------------------------------------------------------------MKNYKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQRFESIEQVNNLREIQALRRLNPHPNILMLHEVVFDRKSGSLALICELMDMNIYELIRGRRYPLSEKKIMHYMYQLCKSLDHIHRNGIFHRDVKPENILIKQDVLKLGDFGSCRSVYSKQPYTEYISTRWYRAPECLLTDGFYTYKMDLWSAGCVFYEIASLQPLFPGVNELDQISKIHDVIGTPAQKILTKFKQSRAMNFDFPFKKGSGIPLLTTNLSPQCLSLLHAMVAYDPDERIAAHQALQHPYFQEQRKTEKRALGSHRKAGFPEHPVAPEPLSNSCQISKEGRKQKQSLKQEEDRPKRRGPAYVMELPKLKLSGVVRLSSYSSPTLQSVLGSGTNGRVPVLRPLKCIPASKKTDPQKDLKPAPQQCRLPTIVRKGGR-", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ******************:******************:********.***************** ********************************:******** ***********:****************:*************************************************************************************.** **********.***************:**:******************************* ** :*.::*..**:* *:..:.**. *:. .:*:***** *.*::**.:.:*:**: : *****:***:.:*** ***:*:****:*:**:********* ..****.***:** :: :**** ****. ", "identical_positions": 345, "similar_positions": 55, "identity": "67.25%" }, { "cls_id": "homologset.agr.RGD:1309275", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WTR6-1", "uniprot_id": "XCT_MOUSE", "id": "Q9WTR6-1", "name": "Cystine/glutamate transporter", "aln": "-----------------------------------MVRKPVVATISKG------GYLQGNMSGRLPSMGDQEPPGQEK----VVLKKKITLLRGVSIIIGTVIGSGIFISPKGILQNTG-SVGMSLVFWSACGVLSLFGALSYAELGTSIKKSGGHYTYILEVFGPLLAFVRVWVELLVIRPGATAVISLAFGRYILEPFF-IQCEIPELAIKLVTAVGITVVMVLNSTSVSWSARIQIFLTFCKLTAILIIIVPGVIQLIKG-----QTHHFKDAFSGRDTSLMG--LPLAFYYGMYAYAGWFYLNFITEEVDNPEKTIPLAICISMAIITVGYVLTNVAYFTTISAEELLQSS-AVAVTFSERLLG--KFSLAVPIFVALSCFGSMNGGVFAVSRLFYVASREGHLPEILSMIHVHKHTP----LPAVIVLHPLTMVMLF-SGDLYSLLN-FLSFARWLFMGLAVAGLIYLRYKRP----DMHRPFKVPLFIPALFSFTCLFMVVLSLYSDP----------------------FSTGVGFLITLTGVPAY-------------------YLFIVWDKKPKWFRRLSDRITRTLQIILEVVPEDSKEL--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LY33-1", "uniprot_id": "A0ABK0LY33_RAT", "id": "A0ABK0LY33-1", "name": "Cystine/glutamate transporter", "aln": "MAERRNDSIHIWLGESLGNCNTTAYQDWQQSFVRWASRKPVVATISKG------GYLQGNVSGRLPSVGDQEPPGHEK----VVLKKKITLLRGVSIIIGTVIGSGIFISPKGILQNTG-SVGMSLVFWSACGVLSLFGALSYAELGTSIKKSGGHYTYILEVFGPLLAFVRVWVELLVIRPGATAVISLAFGRYILEPFF-IQCEIPELAIKLVTAVGITVVMVLNSTSVSWSARIQIFLTFCKLTAILIIIVPGVIQLIKG-----QTHHFKDAFSGRDTNLMG--LPLAFYYGMYAYAGWFYLNFITEEVDNPEKTIPLAICISMAIITVGYVLTNVAYFTTISAEELLQSS-AVAVTFSERLLG--KFSLAVPIFVALSCFGSMNGGVFAVSRLFYVASREGHLPEILSMIHVHKHTP----LPAVIVLHPLTMIMLF-SGDLYSLLN-FLSFARWLFMGLAVAGLIYLRYKRP----DMHRPFKVPLFIPALFSFTCLFMVVLSLYSDP----------------------FSTGVGFLITLTGVPAY-------------------YLFIVWDKKPKWFRRLSDRITRTLQIILEVVPEDSKEL--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UPY5-1", "uniprot_id": "XCT_HUMAN", "id": "Q9UPY5-1", "name": "Cystine/glutamate transporter", "aln": "-----------------------------------MVRKPVVSTISKG------GYLQGNVNGRLPSLGNKEPPGQEK----VQLKRKVTLLRGVSIIIGTIIGAGIFISPKGVLQNTG-SVGMSLTIWTVCGVLSLFGALSYAELGTTIKKSGGHYTYILEVFGPLPAFVRVWVELLIIRPAATAVISLAFGRYILEPFF-IQCEIPELAIKLITAVGITVVMVLNSMSVSWSARIQIFLTFCKLTAILIIIVPGVMQLIKG-----QTQNFKDAFSGRDSSITR--LPLAFYYGMYAYAGWFYLNFVTEEVENPEKTIPLAICISMAIVTIGYVLTNVAYFTTINAEELLLSN-AVAVTFSERLLG--NFSLAVPIFVALSCFGSMNGGVFAVSRLFYVASREGHLPEILSMIHVRKHTP----LPAVIVLHPLTMIMLF-SGDLDSLLN-FLSFARWLFIGLAVAGLIYLRYKCP----DMHRPFKVPLFIPALFSFTCLFMVALSLYSDP----------------------FSTGIGFVITLTGVPAY-------------------YLFIIWDKKPRWFRIMSEKITRTLQIILEVVPEEDKL---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VB75-1", "uniprot_id": "Q9VB75_DROME", "id": "Q9VB75-1", "name": "", "aln": "---------------------MPAADELQS-----PSSEMVLLTPSSGNPPSSIAQPAANPAEKAQCREGSAESDSSR----VVIKKQLGLLEGVAIILGIIFGSGIFVSPKGVIREVE-SVGASLVIWVLCGLLSMIGALCYAELGTAIPKSGGDYAYIFEAYGSLPAFLYLWDAMMIFVPTTNAIMGLTFASYVLEPFFGGACEIPKIALQLLAAITICFLTYLNSYYMKVTTKMQNVIMFTKIAALVLIILVGLVWMMMG-----NVENFTRPFDNTETDPGK--MSVAFYSGIFSYAGWNYLNFMTEELRDPYRNLPRAIYISLPLVTGIYVLANVAYLAVLSPSEMIASN-AIAVTFGDKILG--VFSLIIPLMVAISAFGGLSVHIMTSSRICFVGARNGHMPAILSHISVKSYTP----LPSLVFLCFLSIVMLV-VSDVYVLIT-YASIVESFFIMLSVSAVLYFRYTRP----CMERPIKVAMWIPALFVIVCAFLVVVPIYVAP----------------------YEVGMGVLITIIGIPFY-------------------YVGVVWKNKPKWVQSTIDSVTFTCQKLFMSAKEEKED---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P50276-1", "uniprot_id": "MUP1_YEAST", "id": "P50276-1", "name": "High-affinity methionine permease", "aln": "---------------------MSEGRTFLSQLNVFNKENYQFSSSTTKK---EVSNSTVDADNGASDFEAGQQFATEL----DQGEKQLGILSCIGLICNRMLGTGVFAVSSTIYTLCG-SVGLALIMWAVGAIIAISGLYVYMEFGTAIPKNGGEKNYLEAIFRKPKFFITCMYAAYIFFLGWAAGNSINTAIMFLTAAD---TEVTKWNQRGIGVAVVFFAFLINSLNVKIGLYLQNILGIFKIGIVLFISITGWVALGGGLKDGYQSHNFRNAFEGTETATAYG-IVNALYSVIWSFVGYSNVNYALGEVKNPVRTLKIAGPTSMVFLAIIYIFVNIAYFAVVPKDKLISSKLILAADFFDIVFGG-QAKRAAAALVGLSALGNVLSVIFSQGRIIQQLGREGVLPFSNFFASSKPFNSPMVGLFQHFIVCTVTILAPP-PGDAYLLVQNLISYPMNIINFAISAGLLWIYWQRRQGKIEWNPPIKAGVFVTGFFTLSNLYLIIAPYVPPSNGESVYSSMPYWIHCVIAWGIFFFGGVYYVVWAQLLPRWGHYKLVSKDVLGEDGFWRVKIAKVYDDTIGDVDTQEDGVIETNIIEHYKSEQEKSL---", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P38734-1", "uniprot_id": "MUP3_YEAST", "id": "P38734-1", "name": "Low-affinity methionine permease", "aln": "------------------------MEPLLFNSGKANPSQDVFIDVEVGDITTKYGSTNTGSFSSMDTVEAQAIKAETARFMEVPQGRHLGVFSTVVLFVSRIMGSGIFAVPSVILLNTGGNKLIYFAIWVFSAAIAFAGLYLFLEFGSWIPKSGGRKNFLERSFERPRLLISVVFSCYSVLTGYALTGSIVFGKYVLSAFG----VTDDSWSKYVSISFIIFAVLIHGVSVRHGVFIQNALGGLKLIMIVLMCFAGLYTLFFYKSTGQVAWDLPVTQVEKDSLLSVSSIATAFISSFFCFSGWDTVHTVTSEIKNPVKTLKVSGPLSLIICFVCYTMMNVAYLKVLTYEEIVSAGPLVGSVLFTKLFGPRVGGKFIAFSIAISAASNILVVIYSISRVNQEIFKEGYLPFSIHMSKNWPFDAPLPSISLCGFITIAWILILPKEGESFNYLVSMDGYGNQFFLLLVAIGLFIWRFKHK----NEVPEIRASTFGVLAIITLSLYMLMAPFFADPSLNRVG----------------FLPPYQIMSLLVIVACF------------------FFWLVKFVLLPKFFHYKLLPKITYLHDGLIVTEWVKKPCLC", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . . ::: :: : :: . ::*:*:* .. : . : :* . ::: * : *:*: * *.** :: : :: . .: . .* . . : : : . ::. : :* : *: :::: . * : .: . :: : *: ::.: *: :: *: :* :.: : *: : * : *:**: .: .::: : :. : ::* . :.:*. ..: : : .*: ::* :* . . : .: :: .: : . :: .:: : ::. : : ::: . . : : :. : : . .. ", "identical_positions": 29, "similar_positions": 148, "identity": "4.74%" }, { "cls_id": "homologset.agr.RGD:1309276", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AXZ6-1", "uniprot_id": "PRS40_RAT", "id": "Q6AXZ6-1", "name": "Serine protease 40", "aln": "MWGSRAQQSGPDRGRTCLLAVLLLSFSLFQLHAQDYKPSQTPPPTSDALLKPMGRVQKEICGKTKFQGKIYGGSIAKAERWPWQASLIFRGRHICGAVLIDKNWVASAAHCFKRSLKPSDYRILLGYNELSNPSNYSRQMTLSKVIVHEDYNKLHSQEKDIVLIQLHLPVRYSSHIFPVCVPDQTTKEPSDESCWISGWG---MVTDDKFLQAPFPLLDSEVFLMNDQECEAFFQTPQISITEYDAIKDDMICAGDITNQKSTCRGDSGGPLVCLLDSYWYLVGLASWSGACLEPIHSPSIFTRVSHFSDWIEKKKADTPDVDPSLAPLEETAPSLIGWRNYSAGTTLEPRICTTLLSSQVLLLQSIWLRIL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70169-1", "uniprot_id": "PRS39_MOUSE", "id": "O70169-1", "name": "Inactive serine protease 39", "aln": "MWGSRAQQSGPDRGGACLLAAFLLCFSL--LHAQDYTPSQTPPPTSNTSLKPRGRVQKELCGKTKFQGKIYGGQIAKAERWPWQASLIFRGRHICGAVLIDKTWLLSAAHCFQRSLTPSDYRILLGYNQLSNPSNYSRQMTVNKVILHEDYSKLSRLEKNIVLIQLHHPVIYSTHIFPACVPDGTTKVSPNNLCWISGWG---MLSADKFLQAPFPLLDAEVSLIDEEECTTFFQTPEVSITEYDVIKDDVLCAGDLTNQKSSCRGDSGGPLVCFLNSFWYVVGLANWNGACLEPIHSPNIFTKVSYFSDWIKQKKANTPAADVSSAPLEEMASSLRGWGNYSAGITLKPRISTTLLSSQALLLQSIWLRIL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AB32TJN5-1", "uniprot_id": "A0AB32TJN5_DANRE", "id": "A0AB32TJN5-1", "name": "", "aln": "MWWKTC------------VTLLLLMYVR----------------DSLSNLQVCGRPNPTLN------PRIVGGVNATHGAWPWMVSLQGRYGHFCGGSLINNQWVLTAAHCIVDET-PSSIIVYLGKWRSYVADVNSISRTIRHIIPHPSYSNITK-DNDIALLQLTSTVQYTDYIKPICLADENSNFPRGTNSWVAGWGDIGVLGTGGIRGRTTVSVPLPHPGILQEAELKVYSNADCNNICHGRITPNMICAGTRRGGKATFSGDSGGPLMTKCS-VWVQAGVLSHGYGCAQPN-LPEVFIRVSEYKQWITGNVG----------------------GNLPGFVLFDPRCSLHKVLNRVFCCFG------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** . . :: :** : * : *: ** : : :* ** *. *** .** * *:**. **:: *: :****: . **. : ** . .. * . *: ::* * .*.:: :::*.*:** .* *: :* * *:.* .:: . . .*::*** :: . : . : : :: .:...: . :. *. :::*** . *:: *******: . * .*: . . .* :* *.:* :** :.:** : . * .. :.** . : .:.: . ", "identical_positions": 76, "similar_positions": 104, "identity": "20.43%" }, { "cls_id": "homologset.agr.RGD:1309277", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P0C2C0-1", "uniprot_id": "RM22_RAT", "id": "P0C2C0-1", "name": "Large ribosomal subunit protein uL22m", "aln": "-------------MAAALLRELGALWVPN--------------------------------------------------------LRIWTTQMLR----------VLPQSCIHTSTSLDIS-----------RRWEKKNKIVYPPQLPG----------EPRRPAEIYHCRRQIKYSKDKMWYLAKLIRGMSIDQALAQLEFNDKKGAQIIKEVLLEAQDMAVRDHNVEFRSNLHIAESTSGR-GQCLKRIRYHGRGRFGIMEKVYCHYFVKLVEGPPPRP--EAPRTAVDHAKEYIQQLRSRTIIHTL------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BU88-1", "uniprot_id": "RM22_MOUSE", "id": "Q8BU88-1", "name": "Large ribosomal subunit protein uL22m", "aln": "-------------MAAALLRELGALRVPN--------------------------------------------------------LRIWATQTLR----------VLPPSCIHTSASLDIS-----------RKWEKKNKIVYPPQLPG----------EPRRPAEIYHCRRQIKYSKDKMWYLAKMIRGMSIDQALAQLEFNDKKGAQIIKEVLLEAQDMAVRDHNVEFRSNLHIAESTSGR-GQCLKRIRYHGRGRFGIMEKVYCHYFVKLVEGPPPPP--EVPKTAVDHAKDYIQQLRSRTIIHTL------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NWU5-1", "uniprot_id": "RM22_HUMAN", "id": "Q9NWU5-1", "name": "Large ribosomal subunit protein uL22m", "aln": "-------------MAAAVLGQLGALWIHN--------------------------------------------------------LRSRGKLALG----------VLPQSYIHTSASLDIS-----------RKWEKKNKIVYPPQLPG----------EPRRPAEIYHCRRQIKYSKDKMWYLAKLIRGMSIDQALAQLEFNDKKGAKIIKEVLLEAQDMAVRDHNVEFRSNLYIAESTSGR-GQCLKRIRYHGRGRFGIMEKVYCHYFVKLVEGPPPPP--EPPKTAVAHAKEYIQQLRSRTIVHTL------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VXB5-1", "uniprot_id": "RM22_DROME", "id": "Q9VXB5-1", "name": "Large ribosomal subunit protein uL22m", "aln": "--------------MHKVIRQMSQLRLQAPQGAA--------------------------------------------------LLRSADSSSISPAISPVSPP-ALQSKSLHTAASAGMLCAKWNKYNYGPRKWLEYNKTVHPPQETD----------EEPRNAYVCHMRSNIKYSPDKMWYIAAFVRGMSVDEALKQLNFVLKKGATDVKETILEAQQIAVERHNVEYKSNLWIAESFVGK-GRVFKGVRRHARGRFGKVEYKHCHYFVRLEEGEPPQHYYQEPQTPEQQYESWMEQMRSRKIINSL------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53881-1", "uniprot_id": "RM22_YEAST", "id": "P53881-1", "name": "Large ribosomal subunit protein uL22m", "aln": "MNFHTARISQVGVISRALLSSVSRRWIHVTPISLNNSGGSLFGSITENKPKEGKNRGDEDAGSFSNRLAIASDSSGEAPEVNRDSITIENDKLLQQHIISLQQPEQLASQSLLSPLKREIYEANCKIN----GGFYKKDTIVKLPNSSERYKLKLTKREIEVLEPSVYAQSYRIKSSMKKATLLLRLLGGLDVMKAISQCHFSNKKIAREVAELLQKGVKDGQKLG--LKPEDLYISQIWTGSDGFWRKRVEFKARTRIGIISHPYIHVRCILRTKSVTKRRLAYEAHLKEQKRAPWVQLGDKPIRGVTGGVYKW", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: .:. : : : * . : :. . : : : :. * *: . . : .** * .* : :: *:.: :*: * .* ** * : * : :. . . . .:* *:: * * * :. :.* *:* :. : * * . : . *: .: * ", "identical_positions": 27, "similar_positions": 58, "identity": "8.57%" }, { "cls_id": "homologset.agr.RGD:1309278", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "G3V6A1-1", "uniprot_id": "G3V6A1_RAT", "id": "G3V6A1-1", "name": "", "aln": "--MADFDEIYEEEE----DEERALEEQLLKYSPDPVVVRGSGHVTVFGLSNKFESEFPSSLTGKVAPEEFKASINRVNSCLRKNLPVNVRWLLCGCLCCCCTLGCSMWPVICLSKRTRRSIEKLLEWENNRLYHKLCLHWRLSKRKCETNNMMEYVILIEFLPKTPIFRPD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D9G3-1", "uniprot_id": "CHIC2_MOUSE", "id": "Q9D9G3-1", "name": "Cysteine-rich hydrophobic domain-containing protein 2", "aln": "--MADFDEIYEEEE----DEERALEEQLLKYSPDPVVVRGSGHVTVFGLSNKFESEFPSSLTGKVAPEEFKASINRVNSCLRKNLPVNVRWLLCGCLCCCCTLGCSMWPVICLSKRTRRSIEKLLEWENNRLYHKLCLHWRLSKRKCETNNMMEYVILIEFLPKTPIFRPD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UKJ5-1", "uniprot_id": "CHIC2_HUMAN", "id": "Q9UKJ5-1", "name": "Cysteine-rich hydrophobic domain-containing protein 2", "aln": "--MADFDEIYEEEE----DEERALEEQLLKYSPDPVVVRGSGHVTVFGLSNKFESEFPSSLTGKVAPEEFKASINRVNSCLKKNLPVNVRWLLCGCLCCCCTLGCSMWPVICLSKRTRRSIEKLLEWENNRLYHKLCLHWRLSKRKCETNNMMEYVILIEFLPKTPIFRPD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PFN1-1", "uniprot_id": "A0A8M1PFN1_DANRE", "id": "A0A8M1PFN1-1", "name": "", "aln": "-MMEDFDEIYEEEEEEEEDEDRAAEEQLLKYAPDPVVVRGSGHVTVFGLSNKFESEFPSALTGKVAPEEFKSSINRVNSCLRKALPVNVRWLLCGCLCCCCTLGFSLWPVICLSKRTRRSIEKLLEWENSRLYHKLCLHWRLSKRKCETNNMMEYVILIEFLPKIPIFRPD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q0KI06-1", "uniprot_id": "Q0KI06_DROME", "id": "Q0KI06-1", "name": "Golgin subfamily A member 7/ERF4 domain-containing protein", "aln": "MSFSDFDAIYEDEQ---LDELEHFQDQTVAPVQEPIIIRGAGNMTVFGLSNRFNAEFPCGLLSRVAPEEFKATVGRINGVLKKSLPVNVKWLFCGCVCCCCTLGCSLWPVICLSKRTQLTLDKLFEWENNHLYHKLGLHWRLHKQQCDSNSMMEYVILIEFIPKTPIYRPD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *** ***:*: ** . ::* : :*:::**:*::*******:*::***..* .:*******:::.*:*. *:* *****:**:***:******* *:**********: :::**:****.:***** ***** *::*::*.**********:** **:***", "identical_positions": 101, "similar_positions": 46, "identity": "59.06%" }, { "cls_id": "homologset.agr.RGD:1309279", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZGQ2-1", "uniprot_id": "D3ZGQ2_RAT", "id": "D3ZGQ2-1", "name": "Thymidine kinase 2, mitochondrial", "aln": "MLLRSLRSWAARSLRSMGPGSSGSPGSLDSGAGP----LWAPRRACPPDKDREKDKEKKAVVCIEGNIASGKTTCLEFFSN-TTDVEVLMEPVLKWRNVHGHNPLSLMYHNASRWGLTLQTYVQLTMLDQHTRPQMSPVRLMERSIYSARYIFVENLYRSGKMPEVDYAILSEWFDWIIKNIDVSVDLIVYLRTTPEICYQRLKMRCREEEKVIPVEYLSAIHHLYEEWLVTGSLFPAAAPVLVIEADHNLEKMLELFEQNRARILTPENWKHGP---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R088-1", "uniprot_id": "KITM_MOUSE", "id": "Q9R088-1", "name": "Thymidine kinase 2, mitochondrial", "aln": "MLLRSLRSWAARSPRSVGPGSSGSPGSLDSGAGP----LWAPRRAWPPDKDRENDKEKKAVVCIEGNIASGKTTCLEFFSN-TTDVEVLMEPVLKWRNVHGHNPLSLMYHDASRWGLTLQTYVQLTMLDQHTRPQMSPVRLMERSIYSARYIFVENLYRGGKMPEVDYAILSEWFDWIVRNIDVSVDLIVYLRTTPEICYQRLKMRCREEEKVIPMEYLHAIHRLYEEWLVNGSLFPAAAPVLVIEADHNLEKMLELFEQNRARILTPENWKHGP---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00142-1", "uniprot_id": "KITM_HUMAN", "id": "O00142-1", "name": "Thymidine kinase 2, mitochondrial", "aln": "MLLWPLRGWAARALRCFGPGSRGSP---ASGPGP----RRVQRRAWPPDKEQE--KEKKSVICVEGNIASGKTTCLEFFSN-ATDVEVLTEPVSKWRNVRGHNPLGLMYHDASRWGLTLQTYVQLTMLDRHTRPQVSSVRLMERSIHSARYIFVENLYRSGKMPEVDYVVLSEWFDWILRNMDVSVDLIVYLRTNPETCYQRLKKRCREEEKVIPLEYLEAIHHLHEEWLIKGSLFPMAAPVLVIEADHHMERMLELFEQNRDRILTPENRKHCP---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N0Z5-1", "uniprot_id": "A0A8M1N0Z5_DANRE", "id": "A0A8M1N0Z5-1", "name": "Thymidine kinase 2, mitochondrial", "aln": "MIVNSFKGLCRVVLPLYSHKSLSTNILVRHRAALGKHLLGHWRSSTSHGKLVRNGEGKKSVICLEGNIASGKTTCLEYFSK-TSDIEVLTEPVSKWRNVQGCNPLGLMYQDPTRWGLTLQTYVQLTMLDQHVSPMTAPIRMMERSIYSAKYIFVENLYKSGKMPEVDFAVLSEWFEWIIKNISLPVDLIVYLQTSPQTCHERLKQRCREEEKVIPLEYLESIHNLYEDWLIHQKSFHVPAPVLVIPADHDLKKMLHQFEENREKILMAR---------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9XZT6-1", "uniprot_id": "DNK_DROME", "id": "Q9XZT6-1", "name": "Deoxynucleoside kinase", "aln": "---MAEAASCARKGTKYAEGT------------------------------------QPFTVLIEGNIGSGKTTYLNHFEKYKNDICLLTEPVEKWRNVNGVNLLELMYKDPKKWAMPFQSYVTLTMLQSHTAPTNKKLKIMERSIFSARYCFVENMRRNGSLEQGMYNTLEEWYKFIEESIHVQADLIIYLRTSPEVAYERIRQRARSEESCVPLKYLQELHELHEDWLIHQRR-PQSCKVLVLDADLNLENIGTEYQRSESSIFDAISSNQQPSPVLVSPSKRQRVAR", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . : : .: :****.***** *:.*.: .*: :* *** *****.* * * ***::..:*.:.:*:** ****: *. * :::*****.**:* ****: :.*.: : : *.**:.:* ..: : .***:**:*.*: .::*:: *.*.**. :*::** :*.*:*:**: .. ***: ** .::.: ::... *: . ", "identical_positions": 80, "similar_positions": 86, "identity": "27.59%" }, { "cls_id": "homologset.agr.RGD:1309280", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "B5DF29-1", "uniprot_id": "B5DF29_RAT", "id": "B5DF29-1", "name": "Activator 1 subunit 5", "aln": "MEIRLLVRCHCAPNARRATSYCIRDERPRVEKYRPQTLADLISHQDILSTIQKFISEDRLPHLLLYGPPGTGKTSTILACAKQLYKDKEFGSMVLELNASDDRGIDIVRGPILSFASTRTIFKRGFKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVVQEENVDISEDGMKALVTLSSGDMRRALNILQSTNMAFG-----KVTEETVYTCTGHPLKTDIANILDWMLN-QDFTTAYKNIMELKTLKGLALHDILTEVHLFVHRVDFPSS-VRMHLLTKMADIEYRLSVGTSEKIQLSSLIAAFQVTRDLIVAEA--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D0F6-1", "uniprot_id": "RFC5_MOUSE", "id": "Q9D0F6-1", "name": "Replication factor C subunit 5", "aln": "-------MTAAAPSQQRPAAARARN-LPWVEKYRPQTLADLISHQDILSTIQKFISEDRLPHLLLYGPPGTGKTSTILACAKQLYKDKEFGSMVLELNASDDRGIDIVRGPILSFASTRTIFKKGFKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVVQEENVDISEDGMKALVTLSSGDMRRALNILQSTNMAFG-----KVTEETVYTCTGHPLKTDIANILDWMLN-QDFTTAYKNIMELKTLKGLALHDILTEVHLFVHRVDFPSS-VRIHLLTKMADIEYRLSVGTSEKIQLSSLIAAFQVTRDLIVAEA--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P40937-1", "uniprot_id": "RFC5_HUMAN", "id": "P40937-1", "name": "Replication factor C subunit 5", "aln": "------METSALKQQEQPAATKIRN-LPWVEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYGPPGTGKTSTILACAKQLYKDKEFGSMVLELNASDDRGIDIIRGPILSFASTRTIFKKGFKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNILQSTNMAFG-----KVTEETVYTCTGHPLKSDIANILDWMLN-QDFTTAYRNITELKTLKGLALHDILTEIHLFVHRVDFPSS-VRIHLLTKMADIEYRLSVGTNEKIQLSSLIAAFQVTRDLIVAEA--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VKW3-1", "uniprot_id": "Q9VKW3_DROME", "id": "Q9VKW3-1", "name": "Activator 1 subunit 5", "aln": "------MSETSGPAVR----------MPWVEKYRPSGLDDLISHEEIISTITRFISRKQLPHLLFYGPPGTGKTSTILACARQLYSPQQFKSMVLELNASDDRGIGIVRGQILNFASTRTIFCDTFKLIILDEADAMTNDAQNALRRIIEKYTDNVRFCVICNYLSKIIPALQSRCTRFRFAPLSQDQMMPRLEKIIEAEAVQITEDGKRALLTLAKGDMRKVLNVLQSTVMAFD-----TVNEDNVYMCVGYPLRQDIEQILKALLSGSSLEDSFKTVESAKYARGLALEDIITELHLFVMRLELPMS-VMNKLIVKLAQIEERLAKGCTEVAQTAALVAAFFICRDMVSMEK--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38629-1", "uniprot_id": "RFC3_YEAST", "id": "P38629-1", "name": "Replication factor C subunit 3", "aln": "------MSTSTEKRSKEN--------LPWVEKYRPETLDEVYGQNEVITTVRKFVDEGKLPHLLFYGPPGTGKTSTIVALAREIYG-KNYSNMVLELNASDDRGIDVVRNQIKDFASTRQIFSKGFKLIILDEADAMTNAAQNALRRVIERYTKNTRFCVLANYAHKLTPALLSRCTRFRFQPLPQEAIERRIANVLVHEKLKLSPNAEKALIELSNGDMRRVLNVLQSCKATLDNPDEDEISDDVIYECCGAPRPSDLKAVLKSILE-DDWGTAHYTLNKVRSAKGLALIDLIEGIVKILEDYELQNEETRVHLLTKLADIEYSISKGGNDQIQGSAVIGAIKASFENETVKANV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * ******. * :: .::::::*: :*:.. :*****:************:* *:::* ::: .*************.::*. * .***** ** ***:*********: *******:**::*.*.***::.** *: *** ******** **. : : *: ::: * :.:: :. :**: *:.****:.**:*** ::. :.:: :* * * * *: :*. :*. .. :. .: . : :**** *:: : :: :: . . :*:.*:*:** :: * .: * ::::.*: : : ", "identical_positions": 128, "similar_positions": 110, "identity": "35.96%" }, { "cls_id": "homologset.agr.RGD:1309281", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P0C5J9-1", "uniprot_id": "SHKB1_RAT", "id": "P0C5J9-1", "name": "SH3KBP1-binding protein 1", "aln": "MAVPTTAVEGVRSRGAPGEVIHLNVGGKRFSTSRQTLTWIPDSFFSSLLSGRISTLKDETGAIFIDRDPTVFAPILNFLRTKELDPRGVHGSSLLHEAQFYGLTPLVRRLQVREELDRSSCGNVLFNGYLPPPVFPVKRRNRHSLVGP-------QQIGGRP-------APVR----RSNTMPPNLGNAGLLGR-------MLDDRAP----------------------------PSPSGQPEEPGMVRLVCGHHNWIAVAYTHFLVCYRLKEASGWQLAFSSPRLDWPIERLALTARVLGGAPG-EHDKMVAAATGSEILLWALQAQGGGSEIGVFHLGVPVEALFFVGNQLIATSHTGRIGVWNAVTKHWQVQEVQPITSYDAAGSFLLLGCSNGSIYYVDVQKFPLRMKDNDLLVSELYRDPAEDGVTALSVYLTPKTS-DSGNWIEIAYGTSSGVVRVIVQHPETVGSGPQLFQTFSVHRSPVTKIMLSEKHLISVCADNNHVRTWSVTRFRGMISTQPGSTPLASFKILALESADGLGGCSAGNDIGPYGERDDQQVFIQKVVPNASQLFVRLSSTGQRVCSVRSVDGSATTAFTVLECEGSRRLGSRPRRYLLTGQANGSLAMWDLTTAMDGLG-----QTPAGGLTEEELMDQLEQCELS----------PLTSSR---ASFPSPSPRTSLTSLHSASSNTSLCGHRGSPSPPQ-------AGARSRGAGSFVDRFKELARGAPE-----LRGPPTPAPRPSTSLGNPLILPKNTLNETSF--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P7W2-1", "uniprot_id": "SHKB1_MOUSE", "id": "Q6P7W2-1", "name": "SH3KBP1-binding protein 1", "aln": "MAVATTAVEGVPSRGAPGEVIHLNVGGKRFSTSRQTLTWIPDSFFSSLLSGRISTLKDETGAIFIDRDPTVFAPILNFLRTKELDPRGVHGSSLLHEAQFYGLTPLVRRLQVREELDRSSCGNVLFNGYLPPPVFPVKRRNRHSLVGP-------QQIGGRP-------APVR----RSNTMPPNLGNAGLLGR-------MLDERAP----------------------------PSPSGQPEEPGMVRLVCGHHNWIAVAYTHFLVCYRLKEASGWQLAFSSPRLDWPIERLALAARVLGGAPG-EHDKMVAAATGSEILLWALQAQGGGSEIGVFHLGVPVEALFFVGNQLIATSHTGRIGVWNAVTKHWQVQEVQPITSYDAAGSFLLLGCSNGSIYYVDVQKFPLRMKDNDLLVSELYRDPAEDGVTALSVYLTPKTS-DSGNWIEIAYGTSSGVVRVIVQHPETVGSGPQLFQTFSVHRSPVTKIMLSEKHLISVCADNNHVRTWSVTRFRGMISTQPGSTPLASFKILALESVDGLGGCSAGNDIGPYGERDDQQVFIQKVVPNASQLFVRLSSTGQRVCSVRSVDGSPTTAFTVLECEGSRRLGSRPRRYLLTGQANGSLAMWDLTTAMDGLG-----QTPAGGLTEEELMDQLEQCELS----------PLASSR---GSFPSPSPRTSLTSLHSASSNTSLYGPRGSPSPPQ-------AEARRRGAGSFVDRCQELARGAPE-----LRWPPTPAPRPSTSLGNPLTALKKTLNETSF--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TBC3-1", "uniprot_id": "SHKB1_HUMAN", "id": "Q8TBC3-1", "name": "SH3KBP1-binding protein 1", "aln": "MAAAATAAEGVPSRGPPGEVIHLNVGGKRFSTSRQTLTWIPDSFFSSLLSGRISTLKDETGAIFIDRDPTVFAPILNFLRTKELDPRGVHGSSLLHEAQFYGLTPLVRRLQLREELDRSSCGNVLFNGYLPPPVFPVKRRNRHSLVGP-------QQLGGRP-------APVR----RSNTMPPNLGNAGLLGR-------MLDEKTP----------------------------PSPSGQPEEPGMVRLVCGHHNWIAVAYTQFLVCYRLKEASGWQLVFSSPRLDWPIERLALTARVHGGALG-EHDKMVAAATGSEILLWALQAEGGGSEIGVFHLGVPVEALFFVGNQLIATSHTGRIGVWNAVTKHWQVQEVQPITSYDAAGSFLLLGCNNGSIYYVDVQKFPLRMKDNDLLVSELYRDPAEDGVTALSVYLTPKTS-DSGNWIEIAYGTSSGGVRVIVQHPETVGSGPQLFQTFTVHRSPVTKIMLSEKHLISVCADNNHVRTWSVTRFRGMISTQPGSTPLASFKILALESADGHGGCSAGNDIGPYGERDDQQVFIQKVVPSASQLFVRLSSTGQRVCSVRSVDGSPTTAFTVLECEGSRRLGSRPRRYLLTGQANGSLAMWDLTTAMDGLG-----QAPAGGLTEQELMEQLEHCELA----------PPAPSAPSWGCLPSPSPRISLTSLHSASSNTSLSGHRGSPSPPQ-------AEARRRGGGSFVERCQELVRSGPD-----LRRPPTPAPWPSSGLGTPLTPPKMKLNETSF--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A6H2EG81-1", "uniprot_id": "A0A6H2EG81_DROME", "id": "A0A6H2EG81-1", "name": "BTB domain-containing protein", "aln": "MSHFTHASS--------SDLVNLNVGGQRFSTSRQTLTWIPDTFFTALLSGRISSLRDEHNAIFIDRDPTLFSIILNYLRTKDIDIKNCEIRALRHEAEYYGITPLTKRLALCEDLNHSSCGDLLFYGFLAAPPMPSNEAVAATSVDESLPSTSASAIGSRPGSMVRVPEPSRSSHSRNSSWDLRLGRTGSTGNGANPPAPMLHSRNPSIDFMRHSRNSSADLNKVFRNEVGLVFSPTQNSNWVDPLRVQIIKAHQNWIAVAYAHFVTCYRVKDSNGWQQVFTSPHIDATIERIAINSKVNTSAAEPLPSKMVAISYGSQIRLWSIQEGGQKTDVGTFNLNVRVEYLFFIGSQLVALSSSGKIGVWHAMTQHWQIQDLVPVLSFDSAGSFLLLGCNNGSIYYIDMQKFPLRIKDNDLLVTELYKDVTLDPITAISVYLTPKTSSISGNWIEIAYGTKSGAVRIIVQHPETAGHGPHLFETFFVHQSPVTKVMLSEKYLVSVCSEYHHVRTWRLTRFRGMLSTQPGSTPEASFKIVSLEATDTSYSYAAGNDFGPYGDYDD-MIFVQKVVPETDQLYVRLASNGDRVCVIRSVDSSTISAFCVLECEVSS-------RFILTGHCNGAIQMWDLTTALALLSKDEPQQKINGGPDTNELLRLLDQCEISNSSCTTPCMSPCLSAMGNGSGMASSIARMKASNIALLNREPAMAMAVQAVQPPAQVQPALPEAVAPAAAIPMADDNNEXDVEAAAXLALVGRVSSFTFHRYSLIFDYQFIFLQFVVCALIYVWVTRLTRGPATGP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: : * . .::::*****:**************:**::*******:*:** .*********:*: ***:****::* :. . :* ***::**:***.:** : *:*::****::** *:*..* :* :. : *. . :*.** * * *..: .**.:* *. **..: * *: ..: :* *::: .*:*******::*:.***:*::.*** .*:**::* .***:*: ::* .* .**** : **:* **::* * :::*.*:*.* ** ***:*.**:* * :*:****:*:*:***:*:: *: *:*:*********.******:*:******:*******:***:* : * :**:********* ***********.** **:*******.* **:**:** **:*****:*****:*:***:: :***** :******:******** *****::**:.* . :****:****: ** :*:*****.:.**:***:*.*:*** :****.*. :** ***** * *::***:.**:: *******: *. * ** :**: *::**:: * .: . :.*. .* . :.: . :.:: : .** . .. .:.: :* .. * .. . * :. : : : : ", "identical_positions": 342, "similar_positions": 204, "identity": "42.59%" }, { "cls_id": "homologset.agr.RGD:1309282", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XI59-1", "uniprot_id": "RNF10_RAT", "id": "Q5XI59-1", "name": "E3 ubiquitin-protein ligase RNF10", "aln": "MPQSSPSTAATASDMDKNSGSNSSSASSGSSKGQQPPRSASAGPAGESKPKSDGKNSNGSKRYNRKREPSYPKNENFSNQSRRSNSQKSKTFNKTPPQRGGGSSKPFSSSSNGGRRDEVAEAQRAEFSPAQFSGPKKINLNHLLNFTFEPRGQAGHFEGSGHGSWGKRNKWGHKPFNKELFLQANCQFVVSEDQDYTANFADPDTLVNWDFVEQVRICSHEVPSCPICLYP-PTAAKITRCGHIFCWACILHYLSLSERT------------WSKCPICYSSVHKKDLKSVVATE-------SRQYVVGDTITMQLMKREKGVLVALPKSK---WMNVDHPISLGDEQHSQYSKLLLASKEQVLHRVVLEEKVALEQQLAEEKHTPESCFIEAALQEVKIREEALSGVAGGRAEVTGVVTALEQLVLMAPLAKESAFQPRKGVLEYLSAFDEEAAQVCSLDPPG-PLALPLVEEEEAVSEPE------ACED-LIADDSLGEGTVCAELSQEEPIAKPGFTQLSSSPCYYFYQ--AEDGQHMFLHPVNVRCLVREYGSLEQSPEKISATVVEIAG-YSMSEDVRQRHRYLSHLPLTCEFSICELALQP-PVVSKETLEMFSDDIEKRKR----QRQKKAREERRRERRIELEENKRQGRYPEVHIPLENLQQFPAFNSYTCSSDSALGPTSTEGHGALSLSPLSRSPGSHADFLLTPLSPTASQGSPSFCVGSLEEDSPFLSFAQMLRVGKAKADGWPKAAPKKDDNSLAPPAPVDSDGESDNSDRVPVPSFQNSFSQAIEAAFMKLDTPATS-DPLS-DRGGRKRKRQKQKLLFSTSVVHTK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UIW5-1", "uniprot_id": "RNF10_MOUSE", "id": "Q3UIW5-1", "name": "E3 ubiquitin-protein ligase RNF10", "aln": "MPQSSPSAAATASDMDKNSGSNSSSASSGSSKGQQPPRSASAGPAGESKPKSDGKNSNGSKRYNRKREPSYPKNENFSNQSRRSNSQKSKTFNKMPPQRGGGSSKPFSSSSNGGRRDEVAEAQRAEFSPAQFSGPKKINLNHLLNFTFEPRGQAGHFEGSGHGGWGKRNKWGHKPFNKELFLQANCQFVVSEDQDYAAHFADPDTLVNWDFVEQVRICSHEVPSCPICLYP-PTAAKITRCGHIFCWACILHYLSLSEKT------------WSKCPICYSSVHKKDLKSVVATE-------SRQYAVGDTITMQLMKREKGVLVALPKSK---WVNVDHPINLGDEQLSQYSKLLLASKEQVLHRVVLEEKGALEQQLAEEKHTPESCFIEAAIQEVKIREEALSGVAGGGGEVTGVVAALEHLVLMAPLATESAFQPRKGVLEYLSAFDDEAAQVCSLDPPG-PLALPLVEEEEAVSEPE------ACEDAEVADDSLGEGTVGPEMSQEEPITKPGFTQLSSSPCYYFYQ--AEDGQHMFLHPVNVRCLVREYGSLEQSPEKISATVVEIAG-YSMSEDVRQRHRYLSHLPLTCEFSICELALQP-PVVSKETLEMFSDDIEKRKR----QRQKKAREERRRERRIEMEENKRQGRYPEVHIPLENLQQFPAFNSYTCPSDSALGPTSTEGHGALSLSPLSRSPGSHADFLLTPLSPTASQGSPSFCVGSLEDDSPFLSFAQMLRVGKAKADGWPKTAPKKDDNSLVPPAPVDSDGESDNSDRVPVPSFQNSFSQAIEAAFMKLDTPATS-DPLSEDRGGKKRKRQKQKLLFSTSVVHTK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N5U6-1", "uniprot_id": "RNF10_HUMAN", "id": "Q8N5U6-1", "name": "E3 ubiquitin-protein ligase RNF10", "aln": "MPLSSPNAAATASDMDKNSGSNSSSASSGSSKGQQPPRSASAGPAGESKPKSDGKNSSGSKRYNRKRELSYPKNESFNNQSRRSSSQKSKTFNKMPPQRGGGSSKLFSSSFNGGRRDEVAEAQRAEFSPAQFSGPKKINLNHLLNFTFEPRGQTGHFEGSGHGSWGKRNKWGHKPFNKELFLQANCQFVVSEDQDYTAHFADPDTLVNWDFVEQVRICSHEVPSCPICLYP-PTAAKITRCGHIFCWACILHYLSLSEKT------------WSKCPICYSSVHKKDLKSVVATE-------SHQYVVGDTITMQLMKREKGVLVALPKSK---WMNVDHPIHLGDEQHSQYSKLLLASKEQVLHRVVLEEKVALEQQLAEEKHTPESCFIEAAIQELKTREEALSGLAGSRREVTGVVAALEQLVLMAPLAKESVFQPRKGVLEYLSAFDEETTEVCSLDTPSRPLALPLVEEEEAVSEPEPEGLPEACDDLELADDNLKEGTICTESSQQEPITKSGFTRLSSSPCYYFYQ--AEDGQHMFLHPVNVRCLVREYGSLERSPEKISATVVEIAG-YSMSEDVRQRHRYLSHLPLTCEFSICELALQP-PVVSKETLEMFSDDIEKRKR----QRQKKAREERRRERRIEIEENKKQGKYPEVHIPLENLQQFPAFNSYTCSSDSALGPTSTEGHGALSISPLSRSPGSHADFLLTPLSPTASQGSPSFCVGSLEEDSPFPSFAQMLRVGKAKADVWPKTAPKKDENSLVPPAPVDSDGESDNSDRVPVPSFQNSFSQAIEAAFMKLDTPATS-DPLSEEKGGKKRKKQKQKLLFSTSVVHTK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W0D8-1", "uniprot_id": "Q9W0D8_DROME", "id": "Q9W0D8-1", "name": "E3 ubiquitin-protein ligase RNF10", "aln": "----------MDSNNSSNSKKQPQSSHHGKSSSAESQRKSSELHTNSNKQRHSRRRNQVPTPRNDQQQQPQQPAKLRPNVDKRPKARGFGGGYDFPSPRGQDGASGSSRLAYSATGYSRSGDFDHELNSVYTQGSKKQNLNHLLNFHCVPRELERGHHHQAQQHHGLSGRK--QRYNKEQFLQANFQFVIRSG-AKAQVNGSPDALIDWSYIEQINIQTTEELQCPICLYP-PVAAKLTRCGHAYCWPCLLHYLSLSDKT------------WRKCPICYDAIHAGDLKSCTIEQ-------LRDLQVGEKITFQLMRRRKGSMYIENHVAGLGETIERFPFVSAGEEAKRYSKFLIAKRMDVAAIIERERN---ELLAESDVSCPEDVFIQQALVMLQERVEKLG--------------------VEKPDPKE---------------DEEETAPVLCLETET----------KIDIEKSD--------------DASISSGEASSSLSYSS----------NHNKYYYFYQ--SNDGQNIYLHPLNVKMLQACYGTLDLGPLLIEAQIVQMEQ-HSMDEEHRRKFTCLGHLPLTCQFSVVEVELQP-PVVTGGILKLFKEDILHRKK----ERQRRDREERKREQHINEINDRQMG---KLIASAANLDLSSSHEFPTCGFEEALPAPS----GSVPMNISNQDPG--SRYSSVTLGSPKQEMWPTIGSNSPGGGG---------APLDVQVGAWGRSAPPPPRAVMVP----RTSDEDFEQRSVGHWGLGELLVGALDQKKQKVGAAKSNGAAPAESKKQKKAKGKKMVPLFATGMNRAP", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06436-1", "uniprot_id": "MAG2_YEAST", "id": "Q06436-1", "name": "E3 ubiquitin-protein ligase MAG2", "aln": "-----------------MVEPDMQKKASGGSGGSEMDTLNATSNSSKQGVSNNKRNPVSKKKPGNKVSDGRDNAHNYHGEGRRKSSKQ---------QRSRTPYKETSTRINDQDIDLSIQEEILGGNFKLRGRKTQVSINHLLNFQLPEVEREKSRSSSSKKSN--RRRDEHVHLHGDTFVNVNYRLLVDDRFDYPEQNCNPNVPVDQEKILRVIVP--KGQNCSICLSEEPVAPRMVTCGHIFCLSCLLNFFSIEETVKNKETGYSKKKKYKECPLCGSIIGPKRVKPVLYEDDFDVTRLNQKPEPGATVHLQLMCKPHGSLLPLPVAL-----------HLDPLKCGNFPPANLGSIKHYAHIMKCGVSYSLELYQKDIVAIQEQYEIDKAIYNDSGKFVKQS-------------------------------------------IENINDQISTLLAAT-----------TDLSPLS---------------NDINNGLDNFHFDDDLLT------KYDDSSAYFFYQTLVASSTKYFLSPLDVKILLTIFHYYSKFPESIETTVENIHYDTVVTEQLIRRYKYIGHLPIGTEIALLDLDWRKIPFLPKEIYEQFAHELKQRRRKFTMKKQKEDKEKKLYEKRLEQEHAEFYRKENGNSLKFEDSVQMATHYESIVSS-------------SIPLNSLG----------ISMLGP------PTNSCSTPQKQ----------APSHTKRTIWGTSIAVTEDE--------KASKENKE--------FQDMLLQRIRQEDSSDVTDSTDSPPTSNGKRGRKKKGK--VMLFSSNHQALG", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .. * * . : : :... . :. . . : . . . .:* .:: *. . * . . .: .:****** ..: : : : *::.* :::: . . .*:. :: . : :: : : .*.*** *.*.::. *** :* .*:*:::*:.: . : :**:* . : :*. : :. * .: :*** : :* : : .:. :.. . : . * . *. *: *: . : . :: : * . :. . .: .* . . . . *:*** .. : :* *::*: * : . * *.: : :: : *: ::. :.***: :::: :: : *.:. : * .:: :*:: ::*:. :*:: *:::: . . : .:. ::.:. . *.. *: .: ..: * : . :. *. : : : : : . : :. . : : :* * : **::. ", "identical_positions": 70, "similar_positions": 215, "identity": "8.3%" }, { "cls_id": "homologset.agr.RGD:1309283", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LAF0-1", "uniprot_id": "A0ABK0LAF0_RAT", "id": "A0ABK0LAF0-1", "name": "Synphilin-1", "aln": "MEAPEYLDLDEIDFSDDISYSVTSLKTIPALCRRCDSQNEDRPVSSSSWNCGVSTLITNPQKPTGIADVYSKFRPVKRVSPLKHQPETLESNESDDQKN-NTVEYQKGGETDQGPQPEELSPEDGVGGLPGKGSEPSQALGELEHYDLDMDEILDVPYIKSSQQLAPLTKVTSEKRILGLCTTVNGLSAKTCPIVSAETSTPNMAPLCVLSPVKSPHLRKVPSVLRDQHKLPAEESENSPAPGKCGPAFESENHSKDFLNKVFSDPHSRKAEKSGPDCKLRPFRLQTSAAGAKPEEQVNGVSWASAQGAEERTEYLQKVRSILNIVNEGQISLLPHLAADNLDKIHDENGNNLLHVAASKGHAECLQHLTSLMGEDCLNERNAEQLTPAGLAIKNGQLECVRWMVSETEAIAELSCSKDFPSLIHYAGCYGQEKILLWLLQFMQEQGISLDEVDQEGNSAVHVASQHGYLGCIQTLVEYGANVTMQNHAGEKPSQSAERHGHTLCSRYLVVVETCMSLASQVVKLTKQLKEQTVERVTLQSQLQQLLEAQKSEGKSLPSSPSSPSSPASRKSQWKILDADDESTGKSKLGTQEGIQVLG--NLSSRARTKGKDEDSDKILRQLLGKEISENVCTQEKLSLEFQDAQVSSRNSKKIP--LEKRELKLARLRQLMQRSLSESDTDSNNSEDPKNTPVKRVDRPRPQPIVESVENMDSAESLHLMIKKHSVASG-RRFPFGMKASKSLDGHSPSPTSESSEPDLDSHCPSLGMTPPTQPSTEATQCSPDSATAQKVATSPKSALKSPSSKRRTSQNSKLRVTFEEPVVQMEQTSLELNGEKDKERGRAPQRTS---ESGEQMKRPFGTFRSIMESLSGNQNNNNNYQPASQLKTCTLPLTSLGRKTADAKGNPVSPASKGKNKAA-----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99ME3-1", "uniprot_id": "SNCAP_MOUSE", "id": "Q99ME3-1", "name": "Synphilin-1", "aln": "MEAPEYLDLDEIDFSDDISYSVTSLKTIPALCRRCDSQNEDRSVSSSGWNCGVSTLITNPQKPTGIADVYSKFRPVKRVSPLKHQPETLENNENEDQKN-NTVEYQKGGETDQGPQPEELSPEDGVGGLPGKGSEPSQALGELEHYDLDMDEILDVPYIKSSQQLAPLTKVTSEKRILGLCTTINGLSAKTCPIASTENSTPNMTPFCVLSPVKSPHLRKAPTALRDQHKLSTEDSESSPALGKCGPAYESENHSKDFLNKVFSDPHSRKIEKSGPDCKLRSFHLQSSAAGAKTEEPINGMNWTNTQGTEERTEYLKKVRSILNIVNEGQISLLPHLAADNLDKIHDENGNNLLHIAASKGHAECLQHLTSLMGEDCLNERNTEQLTPAGLAIKNGQLECVRWMVSETEAIAELSCSKDFPSLIHYAGCYGQEKILLWLLQFMQEQGISLDEVDREGNSAVHVASQHGYLGCIQTLVEYGANVTMQNHAGEKPSQSAERHGHTLCSRYLVVVETCMSLASQVVKLTKQLKEQTVERVTLQSQLQQLLEAQKSEGKSLPSSPSSPSSPASTKSQWKALDTDEESTGKSKVGAQEGIQVLGSLSVSSRARTKGKDEDSDKILRQLLGKEISENVCTQEKLSLEFQDAQASSRNSKKIP--LEKRELKLARLRQLMQRSLSESDTDSNNSEDPKNTPVKRADRPRPQPIVESVENVDSAESLHLMIKKHSLASG-RRFPFGMKASKSLDGHSPSPTSESSEPDLDSHGPGLGMTPPTQPSTEATQSSPDSTAAQKVATSPKSALKSPSSKRRTSQNSKLRVTFEEPVVQMEQTGLELNGEKDKDKGRAPQRTS---ESGEQMKRPFGTFRSIMESLSGNQNNNNNYQPASQLKTCTLPLTSLGRKTADAKGNPVSPASKGKNKAAMYSSCIHLPSNALVEEHLRDYARHNDIKRNATKTYHMKHTAEPEPRE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y6H5-1", "uniprot_id": "SNCAP_HUMAN", "id": "Q9Y6H5-1", "name": "Synphilin-1", "aln": "MEAPEYLDLDEIDFSDDISYSVTSLKTIPELCRRCDTQNEDRSVSSSSWNCGISTLITNTQKPTGIADVYSKFRPVKRVSPLKHQPETLENNESDDQKNQKVVEYQKGGESDLGPQPQELGPGDGVGGPPGKSSEPSTSLGELEHYDLDMDEILDVPYIKSSQQLASFTKVTSEKRILGLCTTINGLSGKACSTGSSESSSSNMAPFCVLSPVKSPHLRKASAVIHDQHKLSTEETEISPPLVKCGSAYEPENQSKDFLNKTFSDPHGRKVEKTTPDCQLRAFHLQSSAAESKPEEQVSGLNRTSSQGPEERSEYLKKVKSILNIVKEGQISLLPHLAADNLDKIHDENGNNLLHIAASQGHAECLQHLTSLMGEDCLNERNTEKLTPAGLAIKNGQLECVRWMVSETEAIAELSCSKDFPSLIHYAGCYGQEKILLWLLQFMQEQGISLDEVDQDGNSAVHVASQHGYLGCIQTLVEYGANVTMQNHAGEKPSQSAERQGHTLCSRYLVVVETCMSLASQVVKLTKQLKEQTVERVTLQNQLQQFLEAQKSEGKSLPSSPSSPSSPASRKSQWKSPDADDDSVAKSKPGVQEGIQVLGSLSASSRARPKAKDEDSDKILRQLLGKEISENVCTQEKLSLEFQDAQASSRNSKKIP--LEKRELKLARLRQLMQRSLSESDTDSNNSEDPKTTPVRKADRPRPQPIVESVESMDSAESLHLMIKKHTLASGGRRFPFSIKASKSLDGHSPSPTSESSEPDLESQYPGSGSIPPNQPSGDPQQPSPDSTAAQKVATSPKSALKSPSSKRRTSQNLKLRVTFEEPVVQMEQPSLELNGEKDKDKGRTLQRTSTSNESGDQLKRPFGAFRSIMETLSGNQNNNNNYQAANQLKTSTLPLTSLGRKT-DAKGNPASSASKGKNKAA-----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AA54CTR8-1", "uniprot_id": "A0AA54CTR8_DANRE", "id": "A0AA54CTR8-1", "name": "", "aln": "MDVPEYLDLDEIDFTDDLPYSS---KSIPELCRRHDGQNDERQALAINWPRSAASHSGAGLKPTGIADVYSKFRPVKRVSPLKHQPEETQTQTETEGKS---------SETDTPSGKEEPSKSRGLIN--------QALFGELEHYDLDMDEILDVPYIKCTQQAATLPRAPS--------------AGNTHTLVHSESLSS-GTQFCVLSPV----MRKSKSADLRAQSLGFENTHEQIPDSKTG-----------------------------------------ADGGHASRKQARGVSR-------EVDEEAKKSQNILNIVRDGQISLLPHFAAENLELIRDEDGNNLLHVSAAQGHTDCLQHLTSLMGEDCLNERNKQQLTPAGLSVRNGHLECVRWMVSETEAIAELSCTREHPSLIHYAARYGQERVLLWLLQFMQEQAISLDEQDQNGNSAVHVAAQFGHLGCLQTLVEYGSNVTVQNQQCERASQCAERQGHTTCSRYLVVVETCMSLASQVVKLTKQLHEQTTARVALQNQLQLLLQTQEPNGR-----PPSPSCRVPPSDSWP------EMTLTAEVAPENGQWVLK-----------QKHTETDGVMRKLLTKDAAERTHPRDTHDAGAESGAGPGAGPMKRLGVGERRELKLARLKQIMQRSLSESDGDVYPPDE-----TKHMSRPTQLPIPEAEE------------PKNTHSSSERKLSFTHRTSKSVDACNPSPSSDQSDPETR------------------------TEAGDKVTTSPKSALKSPSSRRKTSQNLKLRVTFDEPP------------RKDGAAGDTKAPST-------KEKRPFGAFRSIMETLSGNQNNNNSNSSSSNAQ---------------SPGKHTGKKSKSKTSAV-----------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:.***********:**:.** *:** **** * **::* . : .* . :: ************************** :.: . : *. .*:* . :* . *: . . :********************.:** *.:.:..* :.:: . :*. :. : :****** :** :. :.* *::. . . * * : . ..: *:. * * :* :.*****.:********:**:**: *:**:******::*::**::****************** ::******:::**:*******************:::.*******. ****::***********.***** *::********:*.*:***:*******:***:**: *:.**.***:*** *************************:***. **:**.*** :*::*:.:*: *.***. .. ...* : . .:: . ::* ** *. ::* ::*:** *: :*.. .::. . :.. .. .. * *:********:*:********* * .:: .:: .** ** *: * *:: :*. *::.* ::***:*. .***:*:.*:*: : :.:**:************:*:**** ******:** .** * : :: : *****:******:*********. ..:.: : : *: .. **.*..*. ", "identical_positions": 385, "similar_positions": 214, "identity": "39.73%" }, { "cls_id": "homologset.agr.RGD:1309285", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "F1LTE0-1", "uniprot_id": "TANC2_RAT", "id": "F1LTE0-1", "name": "Protein TANC2", "aln": "-MFRNSLKMLLTGGKSSRKNR----------SSDGGSEEPPDRRQSSVDSRQSRSGPGG-ISTESDCAFEPDYAVPALPVSE---------GDVEQELGPPPSVDEAANTLMTRLGFLLGEKVTEVQPGD------------------QYSMEVQDENQTSAITQRISPCSTLTSSTASPPASSPCSTLPPVSTNATAKDCSYGAVTSPTSTLESRDSGIIATLTNYSENMERTKYVGEAGKELGSGGNLKPWQSQKSSMDS-------------------------------------------------------------------------------------------CLYRVDEN---MAASTYSLNKIPERNLETVLSQSVQSIPLYLMPRPNSVAATSSAHLEDLAYLDEQRHTPLR---------------------------------------------------TSLRMPRQSMSGARTQQDLRVRFAPYRPPDISLKPLLFEVP------------------------------------------------------------------------------------------------------------------------SITTESVFVG----------------------------------RDWVFHEIDAQLQSSNASVNQGVVIVGNIGFG-KTAIISRLVALSCHGTRMRQIASDSPHASPKHVDANRELPLTQAPSAHSSIASG------------------------------------------------------------------------------------------------------------------------------------------SCPGTPEMRRRQE------------EAMRRLASQVVAYHYCQADNAYTCLVPEFVHNVAALLCRSPQLTAYREQLLREPHLQSMLSLRSCVQDPMASFRRGVLEPLENLHKERKIPDEDFIILIDGLNEAEFHKPDYGDTIVSFLSKMIGNFPSWLKLIVTVRTSLQEITKLLPFHRIFLDRLEENEAIDQDLQAYILHRIHSSSEIQNNISLNGKMDNTTFG----KLSSHLKTLSQGSYLYLKLTFDLIEKGYLVLKSSSYKVVPVSLSEVYLLQCNMKFPTQSSFDRVMPLLNVAVASLHPLTDEHIFQAINAG-SIEGTLEWEDFQQRMENLSMFLIKRRDMTRMFVHPSFREWLIWREEGEKTKFLCDPRSGHTLLAFWFSRQEGKLNRQQTIELGHHILKAHIFKGLSKKVGVSSSILQGLWISYSTEGLSMALASLRNLYTPNIKVSRLLILGGANINYRTEVLNNAPILCVQSHLGYTEMVALLLEFGANVDASSESGLTPLGYAAAAGFLSIVVLLCKKRAKVDHLDKNGQCALVHAALRGHLEVVKFLIQCDWTMAGQQQGVFKKSQAIQQALIAAASMGYTEIVSYLLDLPEKDEEEVERAQINSFDSLWGETALTAAAGRGKLDVCRLLLEQGAAVAQPNRRGAVPLFSTVRQGHWQIVDLLLTHGADVNMAD-KQGRTPLMMAASEGHLGTVDFLLAQGASIALMDKEGLTALSWACLKGHLSVVRSLVDNGAATDHADKNGRTPLDLAAFYGDAEVVQFLVDHGAMIEHVDYSGMRPLDRAVGCRNTSVVVTLLKKGAKIGPATWAMATSKPDIMIILLSKLMEEGDMFYKKGKVKEAAQRYQYALKKFP-REGFGEDLKTFRELKVSLLLNLSRCRRKMNDFGMAEEFATKALELKPKSYEAYYARARAKRSSRQFAAALEDLKEAIKLCPNNREIQRLLMRVEEECRQMQQQQ--QPPPPPQQPPEELPEEETEPEPQPEDIYSVQDIFEEEYLEQDVENVSIGLQTEARPSQGLPVIQSPPSSPAHRDSAYISSSPLGSHQVFDFRSNSSVGSPTRQGYQSTSPALSPTHQNSHYRPSPPHTSPAHQGASYRFSPPPVGGQGKEYPSPPPSPLRRGPQYRASPPAESMSIYRSQSGSPVRYQQEANVSQLPGRPKSPLSKMAQRPYQMPQLPVAVPQQGLRLQPAKAQIVRSNQPSSAVHSSTVIPTGAYGQVAHPMASKYQSSQGDMGVSQSRLVYQGSIGGIVGDGRPVQHVQASLSAGAICQHGGLTKEDLPQRPSSAYRGGMRYSQTPQIGRSQSASYYPVCHSKLDLERSSSQLGSPDVSHLIRRPISVNPNEIKPHPPTPRPLLHSQSVGLRFSPSSNSISSTANLTPTFRPSSSIQQMEIPLKPAYDRSCDELSPVSPTQGGYPSEPTRSRTTPFMGIIDKTARTQQYPHLHQQNRTWAVSSVDTVLSPTSPGNLSQPESFSPPSSISNIAFYNKTNNAQNGHLLEDDYYSPHGMLANGSRGDLLERVSQASSYPDVKVARTLPVAQAYQDNLYRQLSRDSRQGQTSPIKPKRPFVESNV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2A690-1", "uniprot_id": "TANC2_MOUSE", "id": "A2A690-1", "name": "Protein TANC2", "aln": "-MFRNSLKMLLTGGKSSRKNR----------SSDGGSEEPPDRRQSSVDSRQSRSGQGG-ISTESDCAFEPDYAVPPLPVSE---------GDVEQELGPPPSVDEAANTLMTRLGFLLGEKVTEVQPSD------------------QYSMEVQDENQTSAITQRISPCSTLTSSTASPPASSPCSTLPPVSTNAAAKDCSYGAVTSPTSTLESRDSGIIATLTNYSENMERTKYVGEGSKELGSGGNLKPWQSQKSSMDS-------------------------------------------------------------------------------------------CLYRVDEN---MAASTYSLNKIPERNLETVLSQSVQSIPLYLMPRPNSVAATSSAHLEDLAYLDEQRHTPLR---------------------------------------------------TSLRMPRQSLSGARTQQDLRVRFAPYRPPDISLKPLLFEVP------------------------------------------------------------------------------------------------------------------------SITTESVFVG----------------------------------RDWVFHEIDAQLQSSNASVNQGVVIVGNIGFG-KTAIISRLVALSCHGTRMRQIASDSPHASPKHVDANRELPLTQAPSAHSSITSG------------------------------------------------------------------------------------------------------------------------------------------SCPGTPEMRRRQE------------EAMRRLASQVVAYHYCQADNAYTCLVPEFVHNVAALLCRSPQLTAYREQLLREPHLQSMLSLRSCVQDPMASFRRGVLEPLENLHKERKIPDEDFIILIDGLNEAEFHKPDYGDTIVSFLSKMIGNFPSWLKLIVTVRTSLQEITKLLPFHRIFLDRLEENEAIDQDLQAYILHRIHSSSEIQNNISLNGKMDNTTFG----KLSSHLKTLSQGSYLYLKLTFDLIEKGYLVLKSSSYKVVPVSLSEVYLLQCNMKFPTQSSFDRVMPLLNVAVASLHPLTDEHIFQAINAG-SIEGTLEWEDFQQRMENLSMFLIKRRDMTRMFVHPSFREWLIWREEGEKTKFLCDPRSGHTLLAFWFSRQEGKLNRQQTIELGHHILKAHIFKGLSKKVGVSSSILQGLWISYSTEGLSMALASLRNLYTPNIKVSRLLILGGANINYRTEVLNNAPILCVQSHLGYTEMVALLLEFGANVDASSESGLTPLGYAAAAGFLSIVVLLCKKRAKVDHLDKNGQCALVHAALRGHLEVVKFLIQCDWTMAGQQQGVFKKSHAIQQALIAAASMGYTEIVSYLLDLPEKDEEEVERAQINSFDSLWGETALTAAAGRGKLDVCRLLLEQGAAVAQPNRRGAVPLFSTVRQGHWQIVDLLLTHGADVNMAD-KQGRTPLMMAASEGHLGTVDFLLAQGASIALMDKEGLTALSWACLKGHLSVVRSLVDNGAATDHADKNGRTPLDLAAFYGDAEVVQFLVDHGAMIEHVDYSGMRPLDRAVGCRNTSVVVTLLKKGAKIGPATWAMATSKPDIMIILLSKLMEEGDMFYKKGKVKEAAQRYQYALKKFP-REGFGEDLKTFRELKVSLLLNLSRCRRKMNDFGMAEEFATKALELKPKSYEAYYARARAKRSSRQFAAALEDLKEAIKLCPNNREIQRLLMRVEEECRQMQQQQQQQPPPPPQQPPQELPEEETEPEPQHEDIYSVQDIFEEEYLEQDVENVSIGLQTEARPSQGLPVIQSPPSSPAHRDSAYISSSPLGSHQVFDFRSNSSVGSPTRQGYQSTSPALSPTHQNSHYRPSPPHTSPAHQGASYRFSPPPVGGQSKEYPSPPPSPLRRGPQYRASPPAESMSVYRSQSGSPVRYQQETNVSQLPGRPKSPLSKMAQRPYQMPQLPVAVPQQGLRLQPAKAQIVRSNQPSSAVHSSTVIPTGAYGQVAHSMASKYQSSQGDMGVSQSRLVYQGSIGGIVGDGRPVQHVQASLSAGAICQHGGLTKEDLPQRPSSAYRGGMRYSQTPQIGRSQSASYYPVCHSKLDLERSSSQLGSPDVSHLIRRPISVNPNEIKPHPPTPRPLLHSQSVGLRFSPSSNSISSTSNLTPTFRPSSSIQQMEIPLKPAYDRSCDELSPVSPTQGGYPSEPTRSRTTPFMGIIDKTARTQQYPHLHQQNRTWAVSSVDTVLSPTSPGNLPQPESFSPPSSISNIAFYNKTNNAQNGHLLEDDYYSPHGMLANGSRGDLLERVSQASSYPDVKVARTLPVAQAYQDNLYRQLSRDSRQGQTSPIKPKRPFVESNV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HCD6-1", "uniprot_id": "TANC2_HUMAN", "id": "Q9HCD6-1", "name": "Protein TANC2", "aln": "-MFRNSLKMLLTGGKSSRKNR----------SSDGGSEEPPDRRQSSVDSRQSRSGQGG-ISTESDCAFEPDYAVPPLPVSE---------GDAEQELGPPPSVDEAANTLMTRLGFLLGEKVTEVQPGD------------------QYSMEVQDENQTSAITQRISPCSTLTSSTASPPASSPCSTLPPISTNATAKDCSYGAVTSPTSTLESRDSGIIATLTSYSENVERTKYAGESSKELGSGGNIKPWQSQKSSMDS-------------------------------------------------------------------------------------------CLYRVDEN---MTASTYSLNKIPERNLETVLSQSVQSIPLYLMPRPNSVAATSSAHLEDLAYLDEQRHTPLR---------------------------------------------------TSLRMPRQSMGGARTQQDLRVRFAPYRPPDISLKPLLFEVP------------------------------------------------------------------------------------------------------------------------SITTESVFVG----------------------------------RDWVFHEIDAQLQSSNASVNQGVVIVGNIGFG-KTAIISRLVALSCHGTRMRQIASDSPHASPKHVDANRELPLTQPPSAHSSITSG------------------------------------------------------------------------------------------------------------------------------------------SCPGTPEMRRRQE------------EAMRRLASQVVAYHYCQADNAYTCLVPEFVHNVAALLCRSPQLTAYREQLLREPHLQSMLSLRSCVQDPMASFRRGVLEPLENLHKERKIPDEDFIILIDGLNEAEFHKPDYGDTIVSFLSKMIGKFPSWLKLIVTVRTSLQEITKLLPFHRIFLDRLEENEAIDQDLQAYILHRIHSSSEIQNNISLNGKMDNTTFG----KLSSHLKTLSQGSYLYLKLTFDLIEKGYLVLKSSSYKVVPVSLSEVYLLQCNMKFPTQSSFDRVMPLLNVAVASLHPLTDEHIFQAINAG-SIEGTLEWEDFQQRMENLSMFLIKRRDMTRMFVHPSFREWLIWREEGEKTKFLCDPRSGHTLLAFWFSRQEGKLNRQQTIELGHHILKAHIFKGLSKKVGVSSSILQGLWISYSTEGLSMALASLRNLYTPNIKVSRLLILGGANINYRTEVLNNAPILCVQSHLGYTEMVALLLEFGANVDASSESGLTPLGYAAAAGYLSIVVLLCKKRAKVDHLDKNGQCALVHAALRGHLEVVKFLIQCDWTMAGQQQGVFKKSHAIQQALIAAASMGYTEIVSYLLDLPEKDEEEVERAQINSFDSLWGETALTAAAGRGKLEVCRLLLEQGAAVAQPNRRGAVPLFSTVRQGHWQIVDLLLTHGADVNMAD-KQGRTPLMMAASEGHLGTVDFLLAQGASIALMDKEGLTALSWACLKGHLSVVRSLVDNGAATDHADKNGRTPLDLAAFYGDAEVVQFLVDHGAMIEHVDYSGMRPLDRAVGCRNTSVVVTLLKKGAKIGPATWAMATSKPDIMIILLSKLMEEGDMFYKKGKVKEAAQRYQYALKKFP-REGFGEDLKTFRELKVSLLLNLSRCRRKMNDFGMAEEFATKALELKPKSYEAYYARARAKRSSRQFAAALEDLNEAIKLCPNNREIQRLLLRVEEECRQMQQPQ--QPPPPPQ-PQQQLP-EEAEPEPQHEDIYSVQDIFEEEYLEQDVENVSIGLQTEARPSQGLPVIQSPPSSPPHRDSAYISSSPLGSHQVFDFRSSSSVGSPTRQTYQSTSPALSPTHQNSHYRPSPPHTSPAHQGGSYRFSPPPVGGQGKEYPSPPPSPLRRGPQYRASPPAESMSVYRSQSGSPVRYQQETSVSQLPGRPKSPLSKMAQRPYQMPQLPVAVPQQGLRLQPAKAQIVRSNQPSPAVHSSTVIPTGAYGQVAHSMASKYQSSQGDIGVSQSRLVYQGSIGGIVGDGRPVQHVQASLSAGAICQHGGLTKEDLPQRPSSAYRGGVRYSQTPQIGRSQSASYYPVCHSKLDLERSSSQLGSPDVSHLIRRPISVNPNEIKPHPPTPRPLLHSQSVGLRFSPSSNSISSTSNLTPTFRPSSSIQQMEIPLKPAYERSCDELSPVSPTQGGYPSEPTRSRTTPFMGIIDKTARTQQYPHLHQQNRTWAVSSVDTVLSPTSPGNLPQPESFSPPSSISNIAFYNKTNNAQNGHLLEDDYYSPHGMLANGSRGDLLERVSQASSYPDVKVARTLPVAQAYQDNLYRQLSRDSRQGQTSPIKPKRPFVESNV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VTS9-1", "uniprot_id": "Q9VTS9_DROME", "id": "Q9VTS9-1", "name": "", "aln": "MPSLQQIALAMEGDQSELQTPPLPINPPPKVMANGIVYGFRTRHLSCIEENDSDSLHGSSIPHAYDMMQQADETFQKLNANEEQDESGSEDGGLENLDDTIAMIDESRLLEADYLDELVAEEQLQEQDEDEEESSDLVDSGNVEEDFWQPSFNRNDIMMTSVYGALNGSLTSEVSSTAAPGYSECATPRKEAEPVYATPEKRRASNRSFDSTCASLTSSLYGGSMNSSLDLKYSSLGGGDSVSGGISGTSTLRGTSVPPMDLSMISSDGVSALDWGSASVSCVLDSGDGNPAEELNEEMAAKCLSAAESDLQSIRRLLEHDASGSVCPSCRISFDKGKRRKLIDTCGHERCYSCMFRNDQCPMCMNSSLKDVDGANAQGYDTGIGGSTSTIVSPLGSPQPQLRSHAQRNAALARYMQQHRQESQSPDYHHRYASNGKLPRAAALSTNGNGFTTGTTQTVTVDVHHQLGGGGGGAAAAAKQLMANGISGHSRSSSMSHNIHAAAYSELSAAPPAFATPPTRRRFFNHKNLRSALTGGSGGGSGVGGGVGGAGGVGGGHRRTASNGGCPIDTASILSGDHTHQHHHRDNQPEGKESNALNTSTCSDSAVTRRRRKNVSNHNLKTSARHGASSENRLNRLSLAGTSVYAGHLSSLVFGKIKSLWSVNSSNSSEAGLNQLAGSDAIDHHSSFLNEKLQKDQLHARLGLLLNDPGSNGNSSSSGSGCEPISAHSTTSTTSSSGVGAASTTTSGSSQNVSPEQTLASGAGMLSGSQLSVATSHGVKEDALSLCGKFKAGCSMLHVYEALPSKSRKGNVRRSTRGQQGSSSSASAASAVGSRVTASSLAAVQLALKPLFFEVPLQEPDPPYVGRQWLVQQLSNILLGTETRVVLINGQPGTGKTAFCLQLVEYSCFGRRQMQDDPDGIYSQLQLGAHCERMRGLASHMVGYHFCQADANLTCQVPDFVHSLAAQLCQAPQLTAYRDYLLSEPHLQDILSVRECIADAERVMKLAILEPLAHLHRAGKIPAKVAVIVVDALCEAEYHRPDHGHTIASFLAQLTPHFPAWLKLVATVRTQMLELVKAPSYTQLTLDSWASSQALQQDMLDYIGARLADSPEIRMNIGGGGGQNSQSGSQPQTKFVSHLQSLSRGSMLYAKLILDLIARGQLVIKSSSYKVLPVSLAQIFLLHFNLRFPTARSFEQAAPILNICLAALYPLTLDEIYYSMEALSHGREALSWPDFMQRFKLLDGFLIKRLDNTYMFFHSSLREWLMRRDEGESNKFLCDARLGHAGIAFRLSRLQAPLSPQLTLELGHHMLKAHLYGGTSLTL-LSPRDLQSYWLAGAADNISSSLGALRNVYSPNLKVSRLVLLAGASPNHRTDYMGGAPILCIAAHEGILPMVSLLLEFGADVGLTNSQGCTPLILAAMRGHCDVVRPLVAAGSSLGQLDITQRCALVHAARMGHLSVVKYLLACDWSPRPHSQDVTR-SVALQQALIGAAAQAHCKILEDLLDLNETEFD----LDVNGMEPSSGELALTAAARHGCIDVVGILLSRGAQIDARNRQGYSALWLAVKEGHWSVVEHLLQRGALLDEPLGQTRKTPLMIAAEEGHLELVDLLLARGAQREAQDHEGFTALSWACLRGHLAAAKTLIEHGCNRHHEDHNGRTALDLAAYQGAASLVIYILEQGGNLEHIDVHGMRPLDRAIACRNIQAVQVFLRKGAKLGPTTWSMAMGKPEILVILLNKLLEDGNVLYRKNRFQEAAHRYQYALRKISGLEQLLERNAIFAQLRTNLLLNLSRCKRKLNELDASIDLATQAIAQKPHSYEGYYARAKARMELGALNEALVDANEAMQQAAQSG----VLCEVVEVLKRIQTELLTRISISSEDQTGRMSNIGGGASVAYESHHEITDL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.: : : *.:*. :. ::* *: *.::..:* * *. *. * :.* :. * ..* *. *: .. . :**: *. *:.*: : * * * *:: :* **. .. :: .****:* *. .:. .. :: : .: * ** * *.: . . * ::: :. * . . * .*. . :. ..** *::* *: * :* .:: :. :* :. *..:* * . .: : :. : *::::*: . :: :: :.:.* ...: .: . .::* * * .* *:: **:.* * :: :**..: .. *::: . . * .:: * .:*.*.* :*. **.. .:.:::. *. :: :.: ** ** * :*: : * ** ***::*.**:**** ** **:***.:** **::*******: ** *****.:**:*.*: *. :: .:**** :**: *** : :*::*.* ***:*:**:*.**.***::: :**:****:.****.: *:.* .: :: ** ..:*::**: ** *: .*.**: **. .* :. : . *: ***::**:** ** ** :*** :* **:*******:****::::**: *::*** **::. *:**:.:*:*:*** :.*: :::* . :*.* ** **:: *. ***** * * **.*.*:****: *:***..*****.* **: :** :** :. *. * *:*****:****:: * * .: :*. **. *:: :::.:* :*.:***:*:**:*****::*.**. *:**: :..*****: :* * **:*******:*. :...* *** ** *. .:* * :.:.:** . :******* ***.***:*: ***: :.*.* : * *:*****.**: .: :*:. **** *.: : ::*.::. ** ****** :* ::* :**.:** : **:* .*: :*::***.:*: ** :** :: . : :****:**.**** **:***:**. *:**:********:***:..::*:::*. .* *:****.*****: * *.:* :::::*. :**:* ********:.*** ..* .:*:****:**:**:** .**:*::***.**:*:*:::*:*.:.:***:******:*:. * : * * :*:..********:**:*::. : ::**:*: **:***.*****:*: . : ** * :**:: ..:. :* .* * :::* : . ..: .:. .. *. :.: *: ", "identical_positions": 524, "similar_positions": 487, "identity": "21.04%" }, { "cls_id": "homologset.agr.RGD:1309287", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A6B6-1", "uniprot_id": "A0A8I6A6B6_RAT", "id": "A0A8I6A6B6-1", "name": "Protein phosphatase 1 regulatory subunit", "aln": "MAELEHLGGKRAESARARRAEQLRRWRGSLTEQEPAERQGAGRQLQTRRGSPRVRFEDGAVFLAACSSGDTDEVKKLLARGADINTVNVDGLTALHQACIDENLDMVKFLVENRANINQQDNEGWTPLHAAASCGYLNIAEYFISHGASVGIVNSEGEVPSDLAEEP---AMKDLLLEQVKKQGVDLEQSRKEEEQQMLQDARQWLNSGKIEDVR-QARSGATALHVAAAKGYSEVLRLLIQAGYELNVQDHDGWTPLHAAAHWGVKEACSILAEALCDMDIRNKLGQTPFDVADEGLVEHLEMLQKKQDVLR------------------------------------------------------------------SEKETRNKLIESDLNS----------------------------KFQSGLFKNKEKMLYEEEIPKSQETEEENKESSSSSSEEEE----------------GEDEVSESETEKEADKKPEVTVNHSNSESKSRIVEQIPTPAQN---------------------------TFSASSARRLSG-LFNKAEEPKDESPSSWRLGLRKTG---SHNMLSEVTNPREALRDRGSSIYRSSSSPRISTLLDDKD---------KERENRSYFSTLVPRRLSGTSDIEEKENRESAVNLVRSGSHTRQLWRDEAKGNETPQTVAPSTYTSTYLKR---------TPYKSQADSTAERT-DSGSSSTPLCVITNRPAPSTANGVPAATVLSSPAADASVEPREQRRSYLTPVRDEEAESLRKARSRQARQTRR--STQGVTLTDLQEAEKTFSRSRAERQAQEQPGE-----------------------------------KLEDSGELEGSTKKQEPSAAP---------------------------------------------------TKEAGEGQQPWGRSLDE-----------------------------------------------------------EPIYHRLRCPTQPDKLTAPVSPSASRPSLYTG----SQLLHTSRASVPDPE---ATTNTTAAKEMDTSEKEEADLDDQSSNRLSVRERRRLRDRRRGTGINFWTKDEDETDVSEEVKEAWHERLSRLESGGSNPTSSDSHSDRASARARREAREARLASLTSRVEEDSSRDYKKLYESALTENQKLKTKLQEAQLELADIKAKLEKMAQQKQEKTSDRSSVLEVEKRERRALERKMSEMEEEMKVLTELKSDNQRLKDENGALIRVISKLSK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BG95-1", "uniprot_id": "MYPT2_MOUSE", "id": "Q8BG95-1", "name": "Protein phosphatase 1 regulatory subunit 12B", "aln": "MAELEHLGGKRAESARARRAEQLRRWRGSLTEQEPAERQGAGRQLQTRRGSPRVRFEDGAVFLAACSSGDTDEVKKLLARGADINTVNVDGLTALHQACIDENLDMVKFLVENRANVNQQDNEGWTPLHAAASCGYLNIAEYFISHGASVGIVNSEGEVPSDLAEEP---AMKDLLLEQVKKQGVDLEQSRKEEEQQMLQDARQWLNSGRIEDVR-QARSGATALHVAAAKGYSEVLRLLIQAGYELNVQDHDGWTPLHAAAHWGVKEACSILAEALCDMDIRNKLGQTPFDVADEGLVEHLEMLQKKQDVLR------------------------------------------------------------------SEKETRNKLIESDLNS----------------------------KFQSGLFKNKEKMLYEEEIPKSQDTEEENKESSSSSSEEEE----------------GEDEVSESETEKEADKKPEATVNHSNSEIKSRIMEQIPAPAQN---------------------------TFSASSARRLSS-LFNKAEEPKDESPSSWRLGLRKTG---SHNMLSEVANSREALRDRGSSIYRSSSSPRISALLDDKD---------KERENKSYFSMLVPRRLSSTSDIEEKENRESAVNLVRSGSHTRQLWRDEAKGSETPQTIAPSTYTSTYLKR---------TPYKSQADSTAEKTADSVSSSTPLCVITNRPAPSTANGVPAATVFSSAGTDPSVEAREKRRSYLTPVRDEEAESLRKARSRQARQTRR--STQGVTLTDLQEAEKTFSRSRAERQAQEQPGE-----------------------------------KLEDPGGLEGSTKKQEPSAAP---------------------------------------------------TKGAGEG-----RSLEE-----------------------------------------------------------EPIYHRLRYPTQPDKPTTPVSPSASRPSLYTG----SHLLRTSRASGPDSENSETSTHATAAKEMDTSEKGEADLDDQSSNRLSVRERRRAKDRRRGTGINFWTNDEDETDVSEEVKEALHERLSRLESGGTNPTSSDSYSDRASARARREAREARLASLTSRVEEDSNRDYKKLYESALTENQKLKTKLQEAQLELADIKAKLEKMAQQKQEKTSDRSSVLEVEKRERRALERKMSEMEEEMKVLTELKSDNQRLKDENGALIRVISKLSK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60237-1", "uniprot_id": "MYPT2_HUMAN", "id": "O60237-1", "name": "Protein phosphatase 1 regulatory subunit 12B", "aln": "MAELEHLGGKRAESARMRRAEQLRRWRGSLTEQEPAERRGAGRQPLTRRGSPRVRFEDGAVFLAACSSGDTDEVRKLLARGADINTVNVDGLTALHQACIDENLDMVKFLVENRANVNQQDNEGWTPLHAAASCGYLNIAEYFINHGASVGIVNSEGEVPSDLAEEP---AMKDLLLEQVKKQGVDLEQSRKEEEQQMLQDARQWLNSGKIEDVR-QARSGATALHVAAAKGYSEVLRLLIQAGYELNVQDYDGWTPLHAAAHWGVKEACSILAEALCDMDIRNKLGQTPFDVADEGLVEHLELLQKKQNVLR------------------------------------------------------------------SEKETRNKLIESDLNS----------------------------KIQSGFFKNKEKMLYEEETPKSQEMEEENKESSSSSSEEEE----------------GEDEASESETEKEADKKPEAFVNHSNSESKSSITEQIPAPAQN---------------------------TFSASSARRFSSGLFNKPEEPKDESPSSWRLGLRKTG---SHNMLSEVANSREPIRDRGSSIYRSSSSPRISALLDNKD---------KERENKSYISSLAPRKLNSTSDIEEKENRESAVNLVRSGSYTRQLWRDEAKGNEIPQTIAPSTYVSTYLKR---------TPHKSQADTTAEKTADNVSSSTPLCVITNRPLPSTANGVTATPVLSITGTDSSVEAREKRRSYLTPVRDEEAESLRKARSRQARQTRR--STQGVTLTDLQEAERTFSRSRAERQAQEQPRE-----------------------------------KPTDTEGLEGSPEKHEPSAVP---------------------------------------------------ATEAGEGQQPWGRSLDE-----------------------------------------------------------EPICHRLRCPAQPDKPTTPASPSTSRPSLYTS----SHLLWTNRFSVPDSESSETTTNTTTAKEMDKNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERLSRLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQKLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMKVLTELKSDNQRLKDENGALIRVISKLSK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M9NEB2-1", "uniprot_id": "M9NEB2_DROME", "id": "M9NEB2-1", "name": "Protein phosphatase 1 regulatory subunit 12B", "aln": "----MSSLDARNNSAMMKRAEQLKRWEESDTNRAAPTPR--------HEHGRRIKFSSGCVFLAACLSGDKDEVVQLLDQGADINTANVDGLTALHQACIDDNLDMVEFLVERGADINRQDNEGWTPLHATASCGFVSIARYLVENGADVAAVNSDGDLALDLAIDVQHMAMIDYMEKMVQELNINVDEARKAEELAMLNDAKKWLRSDAAEVDRPHPKTGATALHVAAAKGYTKVLGLLLAGRGNVDRQDNDGWTPLHAASHWGQRETAEMLVESLADMDIRNYAGQSCIDVADRKIVKFLEELRANKRNKRRPSSQIRISDAMENHVEKTPTKLVRVEVRTDATKDAENVKPNQQIHAVEHPVEEEAPWRRKLPRTPSDSPTNNQVPDRELGTNSSETANDVILRRTQSFENDQKFYQKYNELRARIKANSCPILPANANANAAAANKSNNNNNLSSNNYHNNNNNNNKSDLLLGYAAGTTTTTSTPTTTTTTTSSTFNNTHSNTNNTSTTQQQPAAAAAASAANQLYSVQRSASLKDNSMYYRKPTVTIATSTAATAINSPSTTVQTPPIRSQVTAKIAEKSNNGSSSTASVSDAESSKPPPKQSASNMIKNFFKSFVPPVRDEESETQRKAHAKRVRETRRSTQGVTLDEIKSAEELVKKKNMGMANNNNNNNISTTTTNTISNSGNETSSASSTSAPTPSILGSNEQQDELQPPPPPTTPPPAVIPTTTTATDETEIEEVVSSPPAGQSQNDTTASFTLSAPVRRSLSTEGEADANSDPEGDQDQTVVSASYTIMPRRERLPESSENVESIRSPQKTEPVAKSSSEDKSEEPPHARPTDLPLIPAPAAPSTEAIKSSSAATTPAALESPVRLRDKRGLSGSQESETKSDTASPVSSHPDFNARDSLLSLYARRTTDSSAGGGGVGGGAGVGAGGASGAATSSSTSAAERRPSWRLKFDAGSKFKLEDITSGGTYPPNNSTIIPSAPAVMAAANLSTTTGVQRRISSGPIALNASNQSLNSVGRPVSAPSEGTNNSAYVTPSARKFETNATSTGATTAATTTSNSTSNSVSATSANHTTATAPNATSNHDDKDNDKENDNRTQTVIQRRRKPKRRSTGVVHIDMDELDPERQNESSNNDNE--EKEKESGSERTSRSRLGSTASTATTSESKSS---SSNDKTENGDGIDYKALWEAEKLENDKLRQMLKQKDDEAVQTRATLERFAN-----ATTKNSLSELEKRERRAMERKLSELEEELKQLDAYKSDNHRLKEENAALIRVISKLSK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * :** :*****:**. * *:: .. : :. . *::*..*.****** ***.*** :** :******.**************:*****:****. *::*:***********:****::.**.*::.:**.*. ***:*::. *** : ** * : : *:: .::::::** ** **:**::**.*. * * :.::*************::** **: . ::: ** *********:*** :*:..:*.*:*.****** **: :****. :*:.** *: :: * *:. *.*:: : :*.: :::: : *. :* : .:: ::.*::.. **.: .: * .:.: * . : ... .***:: .* :* .:.* *:::*:* . .. : * .* : ::. :... * :*:. ..: . :: .*.: :. .. :..: *::. : **.: . :. .:..:.:: :*:* * * ... * . .*.* ..: :.*: ..: * .* : . .:. * . :..* : :.. * .. ::. .::.. . . *:... : : * *:: : : : .*: * *::.* : ...::* :* :::* * : * *.** :.. * .. :. *.* .:: :.: : : *:: : :: .:**: : . : : *. * .:. ::.::*:: ..:: : * *.:..:* . :** : :**.**: . ** :.: .:* .: :* .: :..*:: *: . .. **: : *::.: : ..:.*:... *** *:*: **:**: *:: : * .: ::.**:.*: :: :.*: *:*******:***:**:***:* * ****:***:**.***********", "identical_positions": 294, "similar_positions": 380, "identity": "22.7%" }, { "cls_id": "homologset.agr.RGD:1309288", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5BK17-1", "uniprot_id": "IYD1_RAT", "id": "Q5BK17-1", "name": "Iodotyrosine deiodinase 1", "aln": "-----MFLLTPVLVAVVCILVIWVFKNADRSLEEKKEE----ARAQPWVDEDLKDNTEH--LQVEEDTEEWQES--EESVEHILFSHTRYPEQEMRMRSQEFYELLSKRRSIRFISSEPVP-MEVIDNVIKAAGTAPSGAHTEPWTFVVVKDPDMKHKIREIIEEEEEINYMKRMGKRWVTDLKKLRTNWIKEYLDTAPVLILIFKQVHGFAVNGK-KKVHYYNEISVSIACGILLAALQNAGLVTVTTTPLNCGPRLRVLLGRPSHEKLLVLLPVGYPSRGATVPDLKRKTLDQIMVTV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DCX8-1", "uniprot_id": "IYD1_MOUSE", "id": "Q9DCX8-1", "name": "Iodotyrosine deiodinase 1", "aln": "-----MFLLTPVLVAVVCILVVWVFKNADRNLEKKKEE----AQVQPWVDEDLKDSTED--LQVEEDAEEWQEA--EESVEHIPFSHTRYPEQEMRMRSQEFYELLNKRRSVRFISSEHVP-MEVIENVIKAAGTAPSGAHTEPWTFVVVKDPDMKHKIREIIEEEEEINYMKRMGKRWVTDLKKLRTNWIKEYLDTAPVLILIFKQVHGFAANGK-KKVHYYNEISVSIACGLLLAALQNAGLVTVTTTPLNCGPRLRVLLGRPSHEKLLVLLPVGYPSRDATVPDLKRKALDQIMVTV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6PHW0-1", "uniprot_id": "IYD1_HUMAN", "id": "Q6PHW0-1", "name": "Iodotyrosine deiodinase 1", "aln": "-----MYFLTPILVAILCILVVWIFKNADRSMEKKKGEPRTRAEARPWVDEDLKDSSDL--HQAEEDADEWQES--EENVEHIPFSHNHYPEKEMVKRSQEFYELLNKRRSVRFISNEQVP-MEVIDNVIRTAGTAPSGAHTEPWTFVVVKDPDVKHKIRKIIEEEEEINYMKRMGHRWVTDLKKLRTNWIKEYLDTAPILILIFKQVHGFAANGK-KKVHYYNEISVSIACGILLAALQNAGLVTVTTTPLNCGPRLRVLLGRPAHEKLLMLLPVGYPSKEATVPDLKRKPLDQIMVTV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FDV5-1", "uniprot_id": "IYD_DANRE", "id": "E7FDV5-1", "name": "Iodotyrosine deiodinase", "aln": "--MAVFSSLTPVFVAVLCVIIGFLFKNSQRKESRSKQKP-SDQTARPWVDEDLQDDTEISTKDNEENNEDWMDTTDEENLPHVPYSPVQYSVSEMLDRSERFYTLMNLRRSVRFISPEPVP-KEVIDNVIRTAGTAPSGAHTEPWTFVVVSDTDVKHRIREIIEEEEEINYKQRMGNKWVQDLKRLRTNWVKEYLDVAPYLILVFKQAYGILPSGK-KKTHYYNEISVSISCGILLAALQNAGLVTVTTTPLNCGPQLRSLLQRPANEKLLMLLPVGFPASDAKVPDLKRKDLNDIMVLV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E1JIB2-1", "uniprot_id": "IYD_DROME", "id": "E1JIB2-1", "name": "Iodotyrosine deiodinase", "aln": "MDVDELISSSKLLKHWPSLFITLALIWIVKRLFFKGNR----VLKTYNLDEQVEEEVEH----FADLGDELQPA--LEDKPHVPFVPGQNLNP---NGAKRLYELMRGRRSIRSFNSHPKPDLSVIEDCIRAAGTAPSGAHTEPWTYCVVQEPELKRSIREIVEQEELVNYSQRMHPQWVTDLRPLQTNHVKEYLTEAPYLILIFKQTYGLSENGKRMRRHYYNEISTSIAAGILLCALQAAGLASLVTTPLNCGPALRNLLGRPVNEKLLILLPVGYPKDGCTVPDLARKNLSNIMVTF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :: .::: : : . . :**::::. : : :: : *. *: : : ::.:* *: ***:* :. . * .**:: *::**************: **.:.::*: **:*:*:** :** :** :** **: *:** :**** ** ***:***.:*: .** : *******.**:.*:**.*** ***.::.******** ** ** ** :****:*****:* ..**** ** *.:*** .", "identical_positions": 115, "similar_positions": 80, "identity": "38.33%" }, { "cls_id": "homologset.agr.RGD:1309289", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4A4E8-1", "uniprot_id": "D4A4E8_RAT", "id": "D4A4E8-1", "name": "Endonuclease III-like protein 1", "aln": "MNSG-LRIVTRSRSRATR-----------------------------IASEGCR----------------------------EELAP---RETAAEGRKSHKPVRR--------------------PRKKQKVHVAYEVANGEEGEDAEPLKVPVWEPQ-NWQQQLANIRIMRSKKDAPVDQLG--------AEQC--YDITAPPKVRRYQVLLSLMLSSQTKDQVTAGAMQRLR---------ARGLTVESILQTDDDLLGRLIYPVGFWRSKVKFIKQTTAILQQRYEGDIPASVAELVALPGVGPKMAHLAMAVAWGTVSGIAVDTHVHRIANRLKWTK-KMTKSPEETRRNLEEWLP----SEINGLLVGFGQQICLPVHP--------------RCQACLNKALCPAAQGL-------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35980-1", "uniprot_id": "NTH_MOUSE", "id": "O35980-1", "name": "Endonuclease III-like protein 1", "aln": "MNSG-VRMVTRSRSRATR-----------------------------IASEGCR----------------------------EELAP---REAAAEGRKSHRPVRH--------------------PRRTQKTHVAYEAANGEEGEDAEPLKVPVWEPQ-NWQQQLANIRIMRSKKDAPVDQLG--------AEHC--YDASASPKVRRYQVLLSLMLSSQTKDQVTAGAMQRLR---------ARGLTVESILQTDDDTLGRLIYPVGFWRNKVKYIKQTTAILQQRYEGDIPASVAELVALPGVGPKMAHLAMAVAWGTISGIAVDTHVHRIANRLRWTK-KMTKTPEETRKNLEEWLPRVLWSEVNGLLVGFGQQICLPVHP--------------RCQACLNKALCPAAQDL-------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P78549-2", "uniprot_id": "NTH_HUMAN", "id": "P78549-2", "name": "Endonuclease III-like protein 1", "aln": "MTALSARMLTRSRSLGPG-----------------------------AGPRGCR----------------------------EEPGPLRRREAAAEARKSHSPVKR--------------------PRKAQRLRVAYEGSDSEKGEGAEPLKVPVWEPQ-DWQQQLVNIRAMRNKKDAPVDHLG--------TEHC--YDSSAPPKVRRYQVLLSLMLSSQTKDQVTAGAMQRLR---------ARGLTVDSILQTDDATLGKLIYPVGFWRSKVKYIKQTSAILQQHYGGDIPASVAELVALPGVGPKMAHLAMAVAWGTVSGIAVDTHVHRIANRLRWTK-KATKSPEETRAALEEWLPRELWHEINGLLVGFGQQTCLPVHP--------------RCHACLNQALCPAAQGL-------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VIH0-1", "uniprot_id": "Q9VIH0_DROME", "id": "Q9VIH0-1", "name": "Endonuclease III homolog", "aln": "MAKN-VKKLTLANKLAKRGDLIKPTEIKSRPNRADNVRDIEDLVGVSAGAAGSSSSVFFSPVQTRKQRLLNGEAVKKTNIKMEPLSP--ARVAPKKFRKDDRMVTRVQMGSATVVICKVVPDAVDSPVRVDKIREEVEPQIKQEAPEDSPSFSEVQAPHPLWFNHLENIRIMRNSRTAPVDTMG--------CHRC--ADLKADSKTQRFQNLVALMLSSQTKDQTTYEAMNRLK---------DRGLTPLKVKEMPVTELENLLHPVSFYKNKAKYLKQTVEILTDKYGSDIPDNVKDLVALPGVGPKMAHICMAVAWNKITGIGVDVHVHRLSNRLGWVP-KPTKEPEQTRVALEKWLPFSLWSEVNHLFVGFGQTICTPVKP--------------NCGECLNKDICPSAHAETKEKRKKDR----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08214-1", "uniprot_id": "NTH2_YEAST", "id": "Q08214-1", "name": "Endonuclease III homolog 2", "aln": "MREESRSRKRKHIPVDIEE--------------------------VEVRSKYFKKN--------------------------ERTVELVKENKINKDLQNYGGVNIDWIKALK---------PIEYFEWIESRTCDDPRTWGRPITKEEMINDSGAKVPESFLPIYNRVRLMRSKVKTPVDAMGCSMIPVLVSNKCGIPSEKVDPKNFRLQFLIGTMLSAQTRDERMAQAALNITEYCLNTLKIAEGITLDGLLKIDEPVLANLIRCVSFYTRKANFIKRTAQLLVDNFDSDIPYDIEGILSLPGVGPKMGYLTLQKGWGLIAGICVDVHVHRLCKMWNWVDPIKCKTAEHTRKELQVWLPHSLWYEINTVLVGFGQLICMARGK--------------RCDLCLANDVCNARNEKLIESSKFHQ-LEDKE----DIEKVYSHWLDTVTNGITTERHKKK-----", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P31378-1", "uniprot_id": "NTH1_YEAST", "id": "P31378-1", "name": "Endonuclease III homolog 1", "aln": "MQKIS-----KYSSMAILR--------------------------KRPLVKTETGP--------------------------ESELLPEKRTKIKQEEVVPQPVDIDWVKSLP---------NKQYFEWIVVRNGNVPNRWATPLDPSILVTPASTKVPYKFQETYARMRVLRSKILAPVDIIGGSSIPVTVASKCGISKEQISPRDYRLQVLLGVMLSSQTKDEVTAMAMLNIMRYCIDELHSEEGMTLEAVLQINETKLDELIHSVGFHTRKAKYILSTCKILQDQFSSDVPATINELLGLPGVGPKMAYLTLQKAWGKIEGICVDVHVDRLTKLWKWVDAQKCKTPDQTRTQLQNWLPKGLWTEINGLLVGFGQIITKSRNLGDMLQFLPPDDPRSSLDWDLQSQLYKEIQQNIMSYPKWVKYLEGKRELNVEAEINVKHEEKTVEETMVKLENDISVKVED", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * . : * : .:* :*.. :*** :* :* . .: * * *:. ***:**:*: * .: .*:* : : * .*: *.* *.::: * :* :.: .*:* : ::.********.:: : .*. : ** **.**.*: : *. * .:.** *: *** *:* ::***** . * . : : ", "identical_positions": 63, "similar_positions": 65, "identity": "13.55%" }, { "cls_id": "homologset.agr.RGD:1309290", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "F1LR36-1", "uniprot_id": "F1LR36_RAT", "id": "F1LR36-1", "name": "Transcription elongation factor SPT6", "aln": "---MSDFVESEAEESEEEYNHEGEVVPRVTKKFVEEEDDGEEEEEENLDDQDERGNLKDFINDDDDEEEGEEDEG----SDSGDSEDDVGHKKRKRTSFDDRLEDDDFDLIEENLGVKVKRGQK----YRRVKKMSDDD---EDDEEEYGKEEHEKEAIAGEIFQ-DEEGE---EGQEAVEAPMAPPDEEEEDDEESD-------IDDFIVDD---DGQPLKKPKWRKKLPGYTDAALQEAQEIFGVDFD-----YDEFEKY--NEYDEELEEDYE---YEDDEAEGEIRVRPKKTTKKRVSRRSIFEMYEPSELESSHLTDQDNEIRATDLPERFQLRSIPVKAAED---DELEEEADWIYRNAFATPTISLQDSCDYLDRGQPTSSFSRKGPSTVQKIKEALGFMRNQHFEVPFIAFYRKEYVEP------ELHINDLWRVWQWDEKWTQLRIRKENLTRLFEKMQAYQYEQISADPDKPLADGIRALDTTDMERLKDVQSMDELKDVYNHFLLYYGRDIPKMQNAAK---------ASRKKLKRIKEDGDEEGE------GEEAEDEEQRGPELKQASRRDMYTICQSAGLDGLAKKFGLTPEQFGENLRDSYQRHE-TEQFPAEPLELAKDYVCS-------QFPTPEAVLEGARYMVALQIAREPLVRQVLRQTFQERAKLNITPTKKGRKDVDEAHYAYSFKYLKNKPVKELRDDQFLKIGLAEDEGLLTIDISIDMKG-VEGYGNDQTYFEEIKQFYYR-DEFSHQVQEWNRQRTMAIERALQQFLYVQMAKELKNKLLAEARESVVKACSRKLYNWLRVAPYRPDQQVEEDDDFMDENQGKGIRVLGIAFSSARDHPVFCALVNGEGEVTDFLRLPHFTKRRTAWREEEREKKAQDIETLKKFLVNKKPHVVTVAGENRDAQMLIEDVKRIVHELDQGQ-QLSSIGVELVDNELAILYMNSKKSEAEFRDYPPVLRQAVSLARRIQDPLIEFAQVCSSDEDILCLKFHPLQEHVVKEELLNALYCEFINRVNEVGVDVNRAIAHPYSQALIQYVCGLGPRKGTHLLKILKQNNTRLESRTQLVTMCHMGPKVFMNCAGFLKIDTASLG-DSTDSYIEVLDGSRVHPETYEWARKMAVDALEYDESAEDANPAG-----ALEEILENPER---LKDLDLDAFAEELERQGYGDKHITLYDIRAELSCRYKDLRTAYRSPNTEEIFNMLTKETPETFYIGKLIICNVTGIAHRRPQGESYDQA--IRNDETGLWQCPFCQQDNFPELSEVWNHFDSGSCPGQAIGVKTRLDNGVTGFIPTKFLSDKVVKRPE-ERVKVGMTVHCRIMKIDIEKFSADLTCRTSDLMDRNNEWKLPKDTYYDFDAEAADHKQEEDMK-RKQQRTTYIKRVIAHPSFHNINFKQAEKMMETMDQGDVIIRPSSKGENHLTVTWKVSDGIYQHVDVREEGKENAFSLGATLWINSEEFEDLDEIVARYVQPMASFARDLLNHKYYQD----CSGGDRKKLEELLIKTKKEKPTFIPYFICACKELPGKFLLGYQP--RGKPRIEYVTVTPEGFRYRGQIFPTVNGLFRWFKDHYQDPVPGITPSSSSRTRTPASINATPANINLADLTRAVNALPQNMTSQMFS-----AIAAVTGQGQNPNATPAQWASSQYGY------GGSGGGSSAYHVFPTPAQQPVATPLMTPSYS-YTTP--SQPITTPQY--HQLQASTTPQSTQAQPQPSSSSR--------------------------QRQQQPKSNSHAAIDWGKMAEQWLQEKEAERR-------KQKQ-RLTPRP--------------------------------------------SPSPMIESTPMSIAG-------DATPLLDEMDR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62383-1", "uniprot_id": "SPT6H_MOUSE", "id": "Q62383-1", "name": "Transcription elongation factor SPT6", "aln": "---MSDFVESEAEESEEEYNHEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDERGNLKDFINDDDDEEEGEEDEG----SDSGDSEDDVGHKKRKRPSFDDRLEDDDFDLIEENLGVKVKRGQK----YRRVKKMSDDD---EDDEEEYGKEEHEKEAIAGEIFQ-DEEGE---EGQEAVEAPMAPPDEEEEDDEESD-------IDDFIVDD---DGQPLKKPKWRKKLPGYTDAALQEAQEIFGVDFD-----YDEFEKY--NEYDEELEEDYE---YEDDETEGEIRVRPKKTTKKRVSRRSIFEMYEPSELESSHLTDQDNEIRATDLPERFQLRSIPVKAAED---DELEEEADWIYRNAFATPTISLQDSCDYLDRGQPTSSFSRKGPSTVQKIKEALGFMRNQHFEVPFIAFYRKEYVEP------ELHINDLWRVWQWDEKWTQLRIRKENLTRLFEKMQAYQYEQISADPDKPLADGIRALDTTDMERLKDVQSMDELKDVYNHFLLYYGRDIPKMQNAAK---------ASRKKLKRIKEDGDEEGE------GEEAEDEEQRGPELKQASRRDMYTICQSAGLDGLAKKFGLTPEQFGENLRDSYQRHE-TEQFPAEPLELAKDYVCS-------QFPTPEAVLEGARYMVALQIAREPLVRQVLRQTFQERAKLNITPTKKGRKDVDEAHYAYSFKYLKNKPVKELRDDQFLKIGLAEDEGLLTIDISIDMKG-VEGYGNDQTYFEEIKQFYYR-DEFSHQVQEWNRQRTMAIERALQQFLYVQMAKELKNKLLAEARESVVKACSRKLYNWLRVAPYRPDQQVEEDDDFMDENQGKGIRVLGIAFSSARDHPVFCALVNGEGEVTDFLRLPHFTKRRTAWREEEREKKAQDIETLKKFLVNKKPHVVTIAGENRDAQMLTEDVKRIVHELDQGQ-QLSSIGVELVDNELAILYMNSKKSEAEFRDYPPVLRQAVSLARRIQDPLIEFAQVCSSDEDILCLKFHPLQEHVVKEELLNALYCEFINRVNEVGVDVNRAIAHPYSQALIQYVCGLGPRKGTHLLKILKQNNTRLESRTQLVTMCHMGPKVFMNCAGFLKIDTASLG-DSTDSYIEVLDGSRVHPETYEWARKMAVDALEYDESAEDANPAG-----ALEEILENPER---LKDLDLDAFAEELERQGYGDKHITLYDIRAELSCRYKDLRTAYRSPNTEEIFNMLTKETPETFYIGKLIICNVTGIAHRRPQGESYDQA--IRNDETGLWQCPFCQQDNFPELSEVWNHFDSGSCPGQAIGVKTRLDNGVTGFIPTKFLSDKVVKRPE-ERVKVGMTVHCRIMKIDIEKFSADLTCRTSDLMDRNNEWKLPKDTYYDFDAEAADHKQEEDMK-RKQQRTTYIKRVIAHPSFHNINFKQAEKMMETMDQGDVIIRPSSKGENHLTVTWKVSAGIYQHVDVREEGKENAFSLGATLWINSEEFEDLDEIVARYVQPMASFARDLLNHKYYQD----CSGGDRKKLEELLIKTKKEKPTFIPYFICACKELPGKFLLGYQP--RGKPRIEYVTVTPEGFRYRGQIFPTVNGLFRWFKDHYQDPVPGITPSSSNRTRTPASINATPANINLADLTRAVNALPQNMTSQMFS-----AIAAVTGQGQNPNATPAQWASSQYGY------GGSGGGSSAYHVFPTPAQQPVATPLMTPSYS-YTTP--SQPITTPQY--HQLQASTTPQSTQAQPQPSSSSR--------------------------QRQQQPKSNSHAAIDWGKMAEQWLQEKEAERR-------KQKQ-RLTPRP--------------------------------------------SPSPMIESTPMSIAG-------DATPLLDEMDR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7KZ85-1", "uniprot_id": "SPT6H_HUMAN", "id": "Q7KZ85-1", "name": "Transcription elongation factor SPT6", "aln": "---MSDFVESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDEQGNLKGFINDDDDEDEGEEDEG----SDSGDSEDDVGHKKRKRTSFDDRLEDDDFDLIEENLGVKVKRGQK----YRRVKKMSDDE---DDDEEEYGKEEHEKEAIAEEIFQ-DGEGE---EGQEAMEAPMAPPEEEEEDDEESD-------IDDFIVDD---DGQPLKKPKWRKKLPGYTDAALQEAQEIFGVDFD-----YDEFEKY--NEYDEELEEEYE---YEDDEAEGEIRVRPKKTTKKRVSRRSIFEMYEPSELESSHLTDQDNEIRATDLPERFQLRSIPVKGAED---DELEEEADWIYRNAFATPTISLQESCDYLDRGQPASSFSRKGPSTIQKIKEALGFMRNQHFEVPFIAFYRKEYVEP------ELHINDLWRVWQWDEKWTQLRIRKENLTRLFEKMQAYQYEQISADPDKPLADGIRALDTTDMERLKDVQSMDELKDVYNHFLLYYGRDIPKMQNAAK---------ASRKKLKRVREEGDEEGE------GDEAEDEEQRGPELKQASRRDMYTICQSAGLDGLAKKFGLTPEQFGENLRDSYQRHE-TEQFPAEPLELAKDYVCS-------QFPTPEAVLEGARYMVALQIAREPLVRQVLRQTFQERAKLNITPTKKGRKDVDEAHYAYSFKYLKNKPVKELRDDQFLKICLAEDEGLLTTDISIDLKG-VEGYGNDQTYFEEIKQFYYR-DEFSHQVQEWNRQRTMAIERALQQFLYVQMAKELKNKLLAEAKEYVIKACSRKLYNWLRVAPYRPDQQVEEDDDFMDENQGKGIRVLGIAFSSARDHPVFCALVNGEGEVTDFLRLPHFTKRRTAWREEEREKKAQDIETLKKFLLNKKPHVVTVAGENRDAQMLIEDVKRIVHELDQGQ-QLSSIGVELVDNELAILYMNSKKSEAEFRDYPPVLRQAVSLARRIQDPLIEFAQVCSSDEDILCLKFHPLQEHVVKEELLNALYCEFINRVNEVGVDVNRAIAHPYSQALIQYVCGLGPRKGTHLLKILKQNNTRLESRTQLVTMCHMGPKVFMNCAGFLKIDTASLG-DSTDSYIEVLDGSRVHPETYEWARKMAVDALEYDESAEDANPAG-----ALEEILENPER---LKDLDLDAFAEELERQGYGDKHITLYDIRAELSCRYKDLRTAYRSPNTEEIFNMLTKETPETFYIGKLIICNVTGIAHRRPQGESYDQA--IRNDETGLWQCPFCQQDNFPELSEVWNHFDSGSCPGQAIGVKTRLDNGVTGFIPTKFLSDKVVKRPE-ERVKVGMTVHCRIMKIDIEKFSADLTCRTSDLMDRNNEWKLPKDTYYDFDAEAADHKQEEDMK-RKQQRTTYIKRVIAHPSFHNINFKQAEKMMETMDQGDVIIRPSSKGENHLTVTWKVSDGIYQHVDVREEGKENAFSLGATLWINSEEFEDLDEIVARYVQPMASFARDLLNHKYYQD----CSGGDRKKLEELLIKTKKEKPTFIPYFICACKELPGKFLLGYQP--RGKPRIEYVTVTPEGFRYRGQIFPTVNGLFRWFKDHYQDPVPGITPSSSSRTRTPASINATPANINLADLTRAVNALPQNMTSQMFS-----AIAAVTGQGQNPNATPAQWASSQYGY------GGSGGGSSAYHVFPTPAQQPVATPLMTPSYS-YTTP--SQPITTPQY--HQLQASTTPQSAQAQPQPSSSSR--------------------------QRQQQPKSNSHAAIDWGKMAEQWLQEKEAERR-------KQKQ-RLTPRP--------------------------------------------SPSPMIESTPMSIAG-------DATPLLDEMDR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8UVK2-1", "uniprot_id": "SPT6H_DANRE", "id": "Q8UVK2-1", "name": "Transcription elongation factor SPT6", "aln": "---MSDFIESEAEESEEEFE-EKDLKPKKTQRFMEE---DEEEEEENTEDQDEHGNLRGLIDDDDVEEEEEEERGEPPAGEDSDSGEEVRHRRRKR-SFDDYLDDDDLDLIEENLGVKVKRRKKK---YSRVKTMDDEG---DDDDE--------KDLIADEIFTGDGDGEGEVEDGEAVDTLHPRDDEEEEDDEESD-------IDDFIVDD---DGQPITKKKG-KKFSGYTDAALQEAQEIFGGDFD-----FAEFDT---EAYDHAEEEEED---QDDESWD-----RPKKQTKRRVSRRSIFEIYEPSELESSHMTDQDNEIRSTDMPERFQLRAIPVKPAED---DELEEEAEWIYRNAFSTPTISMQESTDYLDRG-TTTNFSRKGPSTIAKIKEALNFMRNQHFEVPFIAFYRKEYVEP------ELNINDLWKVWQWDEKWTQLKTRKQNLTRLFQRMQSYQFEQISADPDKPLADSTRPLDTADMERLKDVQSIDELGDVYNHFLLYYGRDIPKMQNAAK---------GGKKKLKKIKEVSEEDGEEAEV--EEEEEEEEQKGPDLKQASRRDMYSICQSAGLDGLAKKFGLTPEQFGENLRDSYQRHE-TEQFPAEPLELAKDYVCS-------QFNTPEAVLEGARYMVAMQIAREPLVRHVLRQTFQERAKINIKPTKKGKKDVDEAHFAYSFKYLKNKPVKELSGDQFLKMCLAEEEGLLAIDICIDLVG-VKGYG-DQTYFDEIKQFYYR-DEFSHQVQEWNKQRTLAIERSLQQFLYPQMAKELKNKLIAEAKDNIVKSCCKKLYNWLKVAPYRPDQQVEEDDDLMDESQGKGIRVLGVAFASGRDTPVFCSLINGEGEVVDFLRLPYFLKRRNAWREDEREKKQQDVENLKKFLLSKKPHVVAVSGENRDAHMVMEDIKRTISELEQNS-SLPVVGVELVDNELAVLYMNSKKSEADFRDYPPLLRQAVSVARKIQDPLVEFAQVCSTDDDILCLKLHPLQEHVVKEELLSALYCEFINRVNEVGVDVNRAIAHPYTQSLVQYICGLGPRKGSHLLKILKQNNTRLENRTQLVTMCHMGPKVFINCAGFIKIDTASLG-DSTDSYIEVLDGSRVHPETYEWARKMAVDALEYDESAEDANPAG-----ALEEILENPER---LKDLDLDAFAEELERQGYGNKGITLYDIRAELSCRYKDLRAPYRPPNTEEVFNMLTKETPETFYIGKLITCVVTNIAHRRPQGESYDQA--IRNDETGLWQCPFCQQDNFPELSEVWNHFDSGSCPGQAIGVRTRLDNAVMGFIPTKFLSDKVVKHPE-ERVKPGMTVHCRIMKIDIEKFNVDLTCRTSDLSDKNNEWKLPKDTYYDFDAETDDVKQEEEQK-KKQQRTTYIKRVIAHPSFHNINFKQAEKMMESMDQGDVVIRPSSKGENHLTVTWKVADGIYQHVDVREEGKENAFSLGHTLWINTEEFEDLDEITARYVQPMAAFARDLLGHKYFHE----CNGGDRKKMEELLVRTKKEKPTFIPYYISACRDLPGKFLLGYQP--RGKPRIEYVTITPDGFRYRSQIFPTVNGLFRWFKDHYQDPVPGVTPASS-RTRTPASVNATPANINIADLTRAVNSLPRNMTSQMFN-----AIAAVTGQGQNPNTTPAQWASSQYGYSGGSSAGGGGGSSSAYHVFATP-QQPMATPLMTPSYS-YTTPGQQQAMTTPQYPSSTPQSSHGHHQHSSSTPSSSSSR--------------------------VRTPQPKASSHTAVDWGKMAEQWLQEKEAERR-------KQKTPRMTPRP--------------------------------------------SPSPMIESTPMSIAG-------DATPLLDEMDR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W420-1", "uniprot_id": "SPT6H_DROME", "id": "Q9W420-1", "name": "Transcription elongation factor SPT6", "aln": "---MAEFLDSEAEESEEEEELDVNERKRLKKLKAAVSDSSEEEED---DEERLREELKDLIDDNPIEE--DDGSG----YDSDGVGSGKKRKKHEDDDLDDRLEDDDYDLIEENLGVKVERRKR----FKRLRRIHDNE---SDGEEQHVDEGLVREQIAEQLFDENDESIG-----HRSERSHREADDYDDVDTESD-------ADDFIVDD---NGRPIAEKKK-KRRPIFTDASLQEGQDIFGVDFD-----YDDFSKYEEDDYEDDSEGDEY---DEDLGVGDDTRVKKKKALKKKVVKKTIFDIYEPSELKRGHFTDMDNEIRKTDIPERMQLREVPVTPVPEGS-DELDLEAEWIYKYAFCKHTVSEQEKPE-------SREKMRKPPTTVNKIKQTLEFIRNQQLEVPFIAFYRKEYVKP------ELNIDDLWKVYYYDGIWCQLNERKRKLKVLFEKMRQFQLDTLCADTDQPVPDDVRLILDSDFERLADVQSMEELKDVHMYFLLNYSHELPRMQAEQRRKAIQERREAKARRQAAAAENGDDAAEAIVVPEPEDDDDPELIDYQLKQASNSSPYAVFRKAGICGFAKHFGLTPEQYAENLRDNYQRNE-ITQESIGPTELAKQYLSP-------RFMTTDEVIHAAKYVVARQLAQEPLLRKTMREVYFDRARINIRPTKNGMVLIDENSPVYSMKYVAKKPVSDLFGDQFIKLMMAEEEKLLEITFLEEFEGNACANGTPGDYVEESKALYQL-DQFAKHVQEWNKLRAECVQLALQKWVIPDLIKELRSTLHEEAQQFVLRSCTGKLYKWLKVAPYKP--QLPPDFGYEEWSTLRGIRVLGLAYDPDHSVAAFCAVTTVEGDISDYLRLPNILKRKNSYNLEEKAQKLADLRKLSDFIKMKKPHIVVIGAESRDAQNIQADIKEILHELETSE-QFPPIEVEIIDNELAKIYANSKKGESDFKEYPPLLKQAASLARKMQDPLVEYSQLCDADDEILCLRYHPLQERVPREQLLEQLSLQFINRTSEVGLDINLMVQNSRTINLLQYICGLGPRKGQALLKLLKQSNQRLENRTQLVTVCHLGPRVFINCSGFIKIDTSSLG-DSTEAYVEVLDGSRVHPETYEWARKMAIDAMEYDD--EETNPAG-----ALEEILESPER---LKDLDLDAFAVELERQGFGSKSITLYDIRNELSCLYKDYRTPYTKPSAEELFDMLTKETPDSFYVGKCVTAMVTGFTYRRPQGDQLDSANPVRLDSNESWQCPFCHKDDFPELSEVWNHFDANACPGQPSGVRVRLENGLPGFIHIKNLSDRQVRNPE-ERVRVSQMIHVRIIKIDIDRFSVECSSRTADLKDVNNEWRPRRDNYYDYVTEEQDNRKVSDAKARALKRKIYARRVIAHPSFFNKSYAEVVAMLAEADQGEVALRPSSKSKDHLTATWKVADDIFQHIDVREEGKENDFSLGRSLWIGTEEFEDLDEIIARHIMPMALAARELIQYKYYKPNMVTGDENERDVMEKLLREEKANDPKKIHYFFTASRAMPGKFLLSYLP--KTKVRHEYVTVMPEGYRFRGQIFDTVNSLLRWFKEHWLDPT-ATPASASASNLTPLHLMRPPPTISSSSQTSLGPQAPYSVTGSVTGGTPRSGISSAVG-GGGSSAYSITQSITGYGTSG-SSAPGAGVSSSHYGSSSTPSFGAINTPYTPSGQTPFMTPYTPHASQTPRYGHNVPSPSSQSSSSQRHHYGSSSGTGSTPRYHDMGGGGGGGVGGGGGSNAYSMQPHHQQRAKENLDWQLANDAWARRRPQQHQSHQSYHAQQQHHHSQQQPHMGMSMNMGITMSLGRGTGGGGGGGYGSTPVNDYSTGGGHNRGMSSKASVRSTPRTNASPHSMNLGDATPLYDEN--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P23615-1", "uniprot_id": "SPT6_YEAST", "id": "P23615-1", "name": "Transcription elongation factor SPT6", "aln": "MEETGDSKLVPRDEEEIVNDNDETKAPSEEEEGEDVFDSSEEDEDIDEDEDEARKVQEGFIVNDDDEN---EDPG-------TSISKKRRKHKRREREEDDRLSEDDLDLLMENAGVERTKASSSSGKFKRLKRVGDEGNAAESESDNVAASRQDSTSKLEDFFSEDEEEEESGLRNGRNNEYGRDEEDHENRNRTADKGGILDELDDFIEDDEFSDEDDETRQRRIQEKKLLREQSIKQPTQITGLSSDKIDEMYDIFGDGHDYDWALEIENEELENGNDNNEAEEEEIDEETGAIKSTKKKISLQDIYDLEDLKKNLMTEGDMKIRKTDIPERYQELRAGITDYGNMSSEDQELERNWIAEKISVDKNFDAN----------------YDLTEFKEAIGNAIKFITKENLEVPFIYAYRRNYISSREKDGFLLTEDDLWDIVSLDIEFHSLVNKKDYVQRFYAELH---------------IDDPIVTEYFKNQNTASIAELNSLQDIYDYLEFKYANEINEMFINHT-------------------------------------------GKTGKKHLKNSSYEKFKASPLYQAVSDIGISAEDVGENISSQHQIHPPVDHPSSKPVEVIESILNANSGDLQVFTSNTKLAIDTVQKYYSLELSKNTKIREKVRSDFSKYYLADVVLTAKGKKEIQKGSLYEDIKYAINRTPMHFRRDPDVFLKMVEAESLNLLSVKLHMSS-------QAQYIEHLFQIALETTNTSDIAIEWNNFRKLAFNQAMDK-IFQDISQEVKDNLTKNCQKLVAKTVRHKFMTKLDQAPFIPNVRDPKIPKILSLTCGQGR------FGADAIIAVYVNRKG------DFIRDYKIVDN-----PFDKTNPEKFEDTLDNIIQSCQPNAIGINGPNPKTQKFYKRLQEVLHKKQIVDSRGHTIPIIYVEDEVAIRYQNSERAAQEFPNKPPLVKYCIALARYMHSPLLEYANLTS--EEVRSLSIHPHQNLLSSEQLSWALETAFVDIVNLVSVEVNKATDNNYYASALKYISGFGKRKAIDFLQSLQRLNEPLLARQQLITHNILHKTIFMNSAGFLYISWNEKRQKYEDLEHDQLDSTRIHPEDYHLATKVAADALEYDPDTIAEKEEQGTMSEFIELLREDPDRRAKLESLNLESYAEELEKNTGLRKLNNLNTIVLELLDGFEELRNDFHPLQGDEIFQSLTGESEKTFFKGSIIPVRVERFWHN---------------------------------------------------DIICTTNSEVECVVNAQRHAGAQLRRPANEIYEIGKTYPAKVIYIDYANITAEVSLLDHDVKQQYVPISYSKDPSIWDLKQELEDAEEERKLMMAEARAKRTHRVINHPYYFPFNGRQAEDYLRSKERGEFVIRQSSRGDDHLVITWKLDKDLFQHIDIQELEKENPLALGKVLIVDNQKYNDLDQIIVEYLQNKVRLLNEMTSSEKFKS-------GTKKDVVKFIEDYSRVNPNKSVYYFSLNHDNPGWFYLMFKINANSKLYTWNVKLTNTGYFLVNYNYPSVIQLCNGFKTLLKSNSSKNRMNNYR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: :*.* : : : .**:*: ::: : ..:* :: *: : * . . ::::. . ** *.:** **: ** **: : . : *:: : *: .. .: ::* : : : :: :: : :* **** ** : . : :. : :::: :* * . * : * : * : :: . . * : :: ::*: .:*: . :*: * :** **:*** * :. : :: : * :** . ... : . . * ::: *: ::::***** **::*:.. * :*** : * : .* :* : :: .:: *. . :. .: .::.* *:: :: : *..:: .* . *: . . * : : : ...:*::.*: .**: ..:* : : . * *: :. : . ... .:. .: : :::::. :*. :*. : . :: * :* ::: .:** ::. .: * : : :.* * * . .: . *.:. : : :. . ***. * ..: :::: : :: :*::..* :.:. : :: *: . * **: * : . . :* : . ..: *::* : .. :: : .*..:: :*: : : . . .:: . ::. : : : . : : :::*:* * **::. :* : **::: . ::** ::.**:*:::: . ::: .* ** *: : *:* * *:: .. *.:::* : ::*:.*:* **. :*: *:: * * * **:* : :*:*.:**: *. . . : : **.:*:*** *. * *:* **:*** : :* : *.*:* *:.*:*:::* ***:: * .* * ** ::: * : . :*:*: ** *: .:*: *. : * : :. .: :. : .: : :. ::.* * . . ::: ** .:..: : *: : :* : : : . * :*** ** :. . :. : ::*:. :* **:..:**. ***: .::**:*::* *** ::** * :..::::***:* ..:: . .:: : :: . :. : ::: . .*. *:: : ** * * : . * *.: *: . : :* * . ** . ", "identical_positions": 237, "similar_positions": 489, "identity": "12.35%" }, { "cls_id": "homologset.agr.RGD:1309291", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9V8P9-1", "uniprot_id": "TOPRS_DROME", "id": "Q9V8P9-1", "name": "E3 ubiquitin-protein ligase Topors", "aln": "MAEENPGALAANVPYLGVDELGASVIVEPGLEGSNAGGRTLPAAAIKFADLTESGSESGDNEAEEPVSAGPDNANAIGEPGTSASAAEENGTVERNSPPPNCAICLSRCRRKCFTDSCMHQFCFKCLCEWSKIKPECPLCKQPFRTIIHNVRTLDDYDRYPVQTTSPVPTENPSLRYHIVRRPRYTPLVQNQAVIVNDIEAAIAAGAAGEDVLSAAEVAAGRRSYSRFEPYRSELMNYYQHDQDASTSGSLSQLWRRYVYDRKLYALPVSDSVTGHFREWSARFYRNNPAQIHRLMPWIHRDIMCLLRNAAHSVNTVMTLMSDLLPMTSLLGPTFRRRLSPYLGERTSHFIHELFNFARSPYDINGYDHVVQYSARVAEEVEVDLLDMVETQSSNGDDLNLEVGDSDADAINAGFSPDWSPPRVRPSTSVIVTNPGATHSFSVTMASDGSELPGISIRRTTNVGSQTVAINLSMRRPAAVASEEPEVIEIDDGDAAANAEVAAINDGSNTSRRHAGATLPVTAHIELESSSSSGDEDECVFVLELKPPHMRTPEQVSLDSNSDSDVVFVNEQHEAAPDAIAENRSTQSPLDLASRDQGLFMGPSTSGAAANRGKNWKLVMAQTRRLDQLRTLRSIRSKKSRRSSMPARSDSGSSPSSCSSSSFHFSSSSDEDSSDSSTTNSEPPKKKSRKRVANNKRSKKESIGKRTSRKRKAKDQNMEMLEQQQISQKKPQRQPESSSDSPSSSDDESGGDSSESSGQPNTNNNKSSSDSDDDSAVNMQLSALRATLKAEATLEDRKPVKLELQLPDDDQAGPLHSRMTPSPREDNEPGCSAPKRRRSCSHSNQSSQSASLASSSTATSSSAPLSSFAWGAAGFSGDPLMRGHPAMEEHDIANSLIELSTLTQPVNIGLFNEHYNSAENSMGMLSNTLCDSPQTLAADDANLENYFDTDADPEASRERDAYSLEAAIDVVGESELQIAEDTATATEEQDEEDEEDEDQEEDDQEEEKAAEEEEEEEEDDDDSDNHDENDENQGLLPY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "M0R3Z0-1", "uniprot_id": "M0R3Z0_RAT", "id": "M0R3Z0-1", "name": "RING-type E3 ubiquitin transferase", "aln": "----------------MATELSSKCECPSCLECSQSE-----------SDWNFSSRKRGDGSSYSRLSK-------------------------KSTLSPIMQRFLSQCCSNEFETANKEDFTFLTSEEES------------------------SVDFSQTQNLSQTSKKTRPLR-----------------------------------ELTIQELLRKFGDHGKLPPHSLSLSHFRDH---------VVVKFRRALYYSGVWVKYVQG--SGLKRHFSAQYFKRNPSSLHRLIPWLKRELTAVCGDYGYTVKNILTAILHHMTKFNLDSESFTHLLEPYLLQYTRHFLHEFISFVYSSYNMETYDCNAIYQCPVSTWVKK---------------------------KNTVSAPALSPP----------------EDLSFMKSQQGIKQSKRSWSKTG-------------------QSSDSGLKHFPKGHSSKNSQISTTHQNTANER-------------------------------------------------------PVWTKDEWGSDDFKDVVCTTNSLNWAN------LGESRSHTECYRNDNQEKKSESTKLLHG--HVQNLKRPETSPHTFSALVDS----------------------------NRAPPKKYNIRETNVLNPGQQVHDQRKEAEKKKLEESSLKAFQR--LPRERP---------------------------------------------------------------------LINSKFRDRDHSCHCVSEDSNSPITNDKMLASTKKKMVSCSQSSQCVGVGSHHSRKTQRQYSPRTP----RSKSWCVRPISRGQ----------SYISLRESHRSKHCGLSKRSAHGCESTYRVASLSPVHRVQACLTDRKSCKCASKGEGESQTGGHCDSLSYLRTEKCQAPNKQNMKEKHLVGRVRR-------IRTLRHKKPKYQCVGTQTTAELSDDLEDVNNKSQE-------", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . **.:. . ** *:: :* . *. : **..: . :* :.: .* **:* : * : .:* * * * . * .*. * ...:. .** *: *: .:.:: *: .* :: :* : :** :* ::. *.. :* *.:**::::.**:.:***:**::*:: .: : .::*:.::* : . :. .* . :* : *.*** : * **:**::.*. *.*::: ** . *.. *: *: *: :* *** ..:*. :.:* : . * :* *.:. : .: .*.:: *::::: ::.: ..* * :.* ..* : : .* ..*: *. :* * * : . *..* : .*: *. ::.:: :: ::.* ** * **** . :.. : .:: :: :.*:* ::..:: ::: :.:::* :: :: * *:: *. : ** ::: .*: *: ***:*.*. .* * .* . *. . : .:. *: **: * *.* :. : ** :. :..*.: : * : . *: :* . : . :.:.::. . *: * : . . .: :: *. .. .: ...: : :.. : * .** .* :::.:* ", "identical_positions": 139, "similar_positions": 278, "identity": "13.39%" }, { "cls_id": "homologset.agr.RGD:1309292", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9DCM7-1", "uniprot_id": "NACC2_MOUSE", "id": "Q9DCM7-1", "name": "Nucleus accumbens-associated protein 2", "aln": "MSQMLHIEIPNFGNTVLGCLNEQRLLGLYCDVSIVVKGQAFKAHRAVLAASSLYFRDLFSGNSKSAFELPGTVPPACFQQILSFCYTGKLTMAASEQLVVMYTAGFLQIQHIVERGTDLMFKVSSPHCDSQTAMIEDASSEPQSPCNQLQPATAA---YVTSPSVPIPLLTRVKHEAMEMPPASGPGLASKRPLETGPRDGVAVATGAAGTPGTAPLKLPRVSYYGVPSLATLIPSIQQVPYPPGERTSPGASSLPTTDSPTSYHNEEDEEDDEAYDTMVEEQYGQMYIKATGNYAVQEKPEPVPLESRSCVLIRRDLVALPASLISQIGYRCHPKLYSEGDPGEKLELVAGSGVYITRGQLMNCHLCAGVKHKVLLRRLLATFFDRNTLANSCGTGIRSSTSDPSRKPLDSRVLNAVKLYCQNFAPSFKESEMNVIAADMCTNARRVRKRWLPKIKSMLPEGVEMYRSVMGASAASLPLDPEFPSAAPQVFEQRIYAERRSDAATIVALRTDAVNVDLSTSANPAFEANEEVDGGGSVIQEVAAPEQLPADGQSSPQAFEQGNTSSSRPQTPVATATRRPEGTYAGTL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q562B4-1", "uniprot_id": "NACC2_RAT", "id": "Q562B4-1", "name": "Nucleus accumbens-associated protein 2", "aln": "MSQMLHIEIPNFGNTVLGCLNEQRLLGLYCDVSIVVKGQAFKAHRAVLAASSLYFRDLFSGNSKSAFELPGTVPPACFQQILSFCYTGKLTMAASEQLVVMYTAGFLQIQHIVERGTDLMFKVSSPHCDSQTAMIEDASSEPQSPCNQLQPATAA---YATSPSVPIPLLTRVKHEAMEMPPATGPGLASKRPLDTGPRDGVAVATGAAGTPGTAPLKLPRVSYYGVPSLATLIPSIQQVPYPQGERTSPGASSLPTTDSSTSYHNE-DEDDDEAYDTMVEEQYGQMYIKATGNYAVQEKPEPVPLESRSCVLIRRDLVALPASLISQIGYRCHPKLYSEGDPGEKLELVAGSGVYITRGQLMNCHLCAGVKHKVLLRRLLATFFDRNTLANSCGTGIRSSTSDPSRKPLDSRVLNAVKLYCQNFAPSFKESEMNVIAADMCTNARRVRKRWLPKIKSMLPEGVEMYRSVMGASAASLPLDPEFPSAASQVFEQRIYAERRNDAATIVALRTDAVNVDLSTSANPAFEANEEVDGAGSVIQEVAAPEQLPADGQSSPQAFEQGNTSSSRPQTPVATATRRPEGTYAGTL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96BF6-1", "uniprot_id": "NACC2_HUMAN", "id": "Q96BF6-1", "name": "Nucleus accumbens-associated protein 2", "aln": "MSQMLHIEIPNFGNTVLGCLNEQRLLGLYCDVSIVVKGQAFKAHRAVLAASSLYFRDLFSGNSKSAFELPGSVPPACFQQILSFCYTGRLTMTASEQLVVMYTAGFLQIQHIVERGTDLMFKVSSPHCDSQTAVIEDAGSEPQSPCNQLQPAAAAAAPYVVSPSVPIPLLTRVKHEAMELPPA-GPGLAPKRPLETGPRDGVAVAAGAAVAAGTAPLKLPRVSYYGVPSLATLIPGIQQMPYPQGERTSPGASSLPTTDSPTSYHNEEDEEDDEAYDTMVEEQYGQMYIKASGSYAVQEKPEPVPLESRSCVLIRRDLVALPASLISQIGYRCHPKLYSEGDPGEKLELVAGSGVYITRGQLMNCHLCAGVKHKVLLRRLLATFFDRNTLANSCGTGIRSSTSDPSRKPLDSRVLNAVKLYCQNFAPSFKESEMNVIAADMCTNARRVRKRWLPKIKSMLPEGVEMYRTVMGSAAASVPLDPEFPPAAAQVFEQRIYAERRGDAATIVALRTDAVNVDLSAAANPAFDAGEEVDGAGSVIQEVAAPEPLPADGQSPPQPFEQGGGGPSRPQTP-AAAARRPEGTYAGTL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***********************************************************************:****************:***:****************************************:****.*************:** *..******************:*** *****.****:**********:*** :.***********************.***:*** ****************.****** **:********************:*.******************************************************************************************************************************************************************************:***::***:*******.**.************.******************::*****:*.*****.*********** *******.**.****. ..****** *:*:***********", "identical_positions": 540, "similar_positions": 39, "identity": "91.68%" }, { "cls_id": "homologset.agr.RGD:1309293", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "B5DFH3-1", "uniprot_id": "B5DFH3_RAT", "id": "B5DFH3-1", "name": "Protein sprouty homolog 1", "aln": "---------------------------------------------------------------------------------------------------------------------------MDSPSQHDSHTSLVVIQPPA-----------------------VEGRQRLDYDRDTQPATILSLDQIK--AIRGSNEYTEGPSVARRPAPRTAPRPEK-QERTHEIIPANVNSSYVHRPAGHSG------------------NARGSVLSRSTSTGSAASSGSSSSVSSEQGLLGRSPPTRPIPGHRS-----------------DRVIRTQPKQLLVDDLKASLKEDP-------------------TQHKFICEQCGKCKCGECTAPRALPSCLACDRQCLCSAESMVEYGTCMCLVKGIFYHCSNDD-------DGGSYSDNPCSCSQSHCCSRYLCMGALSLCLPCLLCYPPAKGCLKLCRGCYDWTHRPGCRCR--------------NSNTVYCKLESCPSRAQGKPS----------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QXV9-1", "uniprot_id": "SPY1_MOUSE", "id": "Q9QXV9-1", "name": "Protein sprouty homolog 1", "aln": "---------------------------------------------------------------------------------------------------------------------------MDSPSQHGSHTSLVVIQPPA-----------------------VEGRQRLDYDRDTQPATILSLDQIK--AIRGSNEYTEGPSVARRPAPRTAPRPEK-QERTHEIIPANVNSSYEHRPASHPG------------------NARGSVLSRSTSTGSAASSGSSSSVSSEQGLLGRSPPTRPIPGHRS-----------------DRVIRTQPKQLLVEDLKASLKEDP-------------------TQHKFICEQCGKCKCGECTAPRALPSCLACDRQCLCSAESMVEYGTCMCLVKGIFYHCSNDD-------DGGSYSDNPCSCSQSHCCSRYLCMGALSLCLPCLLCYPPAKGCLKLCRGCYDWTHRPGCRCR--------------NSNTVYCKLESCPSRAQGKLS----------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43609-1", "uniprot_id": "SPY1_HUMAN", "id": "O43609-1", "name": "Protein sprouty homolog 1", "aln": "---------------------------------------------------------------------------------------------------------------------------MDPQNQHGSGSSLVVIQQPS-----------------------LDSRQRLDYEREIQPTAILSLDQIK--AIRGSNEYTEGPSVVKRPAPRTAPRQEK-HERTHEIIPINVNNNYEHRHTSHLGHAVLPS------------NARGPILSRSTSTGSAASSGSNSSASSEQGLLGRSPPTRPVPGHRS-----------------ERAIRTQPKQLIVDDLKGSLKEDL-------------------TQHKFICEQCGKCKCGECTAPRTLPSCLACNRQCLCSAESMVEYGTCMCLVKGIFYHCSNDD-------EGDSYSDNPCSCSQSHCCSRYLCMGAMSLFLPCLLCYPPAKGCLKLCRRCYDWIHRPGCRCK--------------NSNTVYCKLESCPSRGQGKPS----------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O44783-1", "uniprot_id": "SPY_DROME", "id": "O44783-1", "name": "Protein sprouty", "aln": "MDRRNGGDPLAPPRPPKLLPRVHRPRAPEPTLSGVDHNAGATASALASGASSAAPVAIHNNNSQQQLSISAAASNNNTISIIPASPDFDDYQIHHLTFLPQRPSSLSRNSSTASSTTATGISVSGSGSVSGSSSSFTRRRPPAPVPLNNSISNNNNNSINNNFLSHFQSAEPASNALGQPPASPVTLAQPRPESERLTNEYVDTPLQHATRSQHPAGQQDNGQTTTHHLLLLPQRNQHLHLQQHQQHLQQQQQQQQQQQQQQHLQHQQNQQHARLATTTQATSVGSDHTDGLLHSHLQNSTTKPPASKQPAPPRLGMGLGLGLGLGLNQPIITKQPTPATQKERMHALEELLQPGGAGGNGGPLVMAGDPSLLNPIVCPRCGRCRCEQCQSPRPLPQTWVCNKTCLCSAESVIDYASCLCCAKALFYHCARDNDLDCDDGNGTPCVDNPCSCGPYKRTQRWGWLGALSIFLPCLWFYWPMRGCMKLCEKCYGRFAGRGCRCQGIGGGGAGSGGGVGSIGSTSSMLPIVPLGVNGSGLGGGVSLSGGVTDGGLNQANGKAMDHGCSAARSILRKGDLTPEKRLLDSSPDY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. . .* :*:. : *: .:. : . *:: ::* * : : * :***.: * : :.* : :: : **.:: ...: * : : :. :* ::* .*:* **. : . :. * .*... * . : : : * .**. .: :*:* : ::* :**:*:* :* :**.**. .*:: *******:::*.:*:* .*.:****:.*: :* . ******. : .*: :**:*: **** * * :**:***. **. ****: . .:. . * * :*. ", "identical_positions": 87, "similar_positions": 111, "identity": "14.77%" }, { "cls_id": "homologset.agr.RGD:1309295", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CZP7-1", "uniprot_id": "CD37L_MOUSE", "id": "Q9CZP7-1", "name": "Hsp90 co-chaperone Cdc37-like 1", "aln": "MEQPWPPPGPWSFPRTGGETEEESD-LDVSPSSSHYSPVPDGGAQMYSHGIELACQKQKEFVKSSVACKWNLAEAQQKLGSLA----------------------------------------LHNSESLDQEHAKAQTAVSELRQREEEWRQKEEALVQRERMCLWNMDAISKD------------VFNKSFINQDKRK-----------------------TEEEDKSQSFMQKYE------QKIRHFG--MLSRWDDSQRFLSDHPHLVCEETAKYLILWCFHLEAEQKGALMEQIAHQAVVMQFIMEMAKNCNV------DPRGCFRLFFQKAKAEE------EGYFEAFKNELEAFKSRVRLYAQS---QSLQPVTVQN-------------------HVPHSGVGCIGSLES-LPQNPD-------------------------SLQCCTPAPLCSVDSVVHK----EDDD-RMMDTV-----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5XIC3-1", "uniprot_id": "CD37L_RAT", "id": "Q5XIC3-1", "name": "Hsp90 co-chaperone Cdc37-like 1", "aln": "MEQPWPPPGPWSFPRTGGETEEESD-LDVSPSSSHYSPVPDGGAQMYSHGIELACQRQKEFVKSSVACKWNLAEAQQKLGSLA----------------------------------------LHNSESLDQEHAKAQTAVSELRQREEEWRQKEEALVQRERTCLWNVDAISKD------------VFNKSFINQDKRK-----------------------TEDEDKSQSFMQKYE------QKIRHFG--MLSRWDDSQRFLSDHPYLVCEETAKYLILWCFHLEAEQKGALMEQIAHQAVVMQFIMEMAKNCNV------DPRGCFRLFFQKAKAEE------EGYFEAFKNELEAFKARVRLYAQS---QSFAPVTVEN-------------------HAPHSGVGCIGSAEP-LPQNPD-------------------------SLQCCPPAPLCSVDSVVHK----EDDD-RMMDTV-----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7L3B6-1", "uniprot_id": "CD37L_HUMAN", "id": "Q7L3B6-1", "name": "Hsp90 co-chaperone Cdc37-like 1", "aln": "MEQPWPPPGPWSLPRAEGEAEEESD-FDVFPSSPRCPQLPGGGAQMYSHGIELACQKQKEFVKSSVACKWNLAEAQQKLGSLA----------------------------------------LHNSESLDQEHAKAQTAVSELRQREEEWRQKEEALVQREKMCLWSTDAISKD------------VFNKSFINQDKRKD----------------------TEDEDKSESFMQKYE------QKIRHFG--MLSRWDDSQRFLSDHPYLVCEETAKYLILWCFHLEAEKKGALMEQIAHQAVVMQFIMEMAKNCNV------DPRGCFRLFFQKAKAEE------EGYFEAFKNELEAFKSRVRLYSQS---QSFQPMTVQN-------------------HVPHSGVGSIGLLES-LPQNPD-------------------------YLQYSISTALCSLNSVVHK----EDDEPKMMDTV-----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A7YY97-1", "uniprot_id": "CD37L_DANRE", "id": "A7YY97-1", "name": "Hsp90 co-chaperone Cdc37-like 1", "aln": "--------------------------------------------------MASLCQRQQHCVKASIASEWQLAEAQDQLCGLE----------------------------------------LHSSESVEQERARALASSTELSHTEHQWRLKERMLG---TLCP----EANRD------------VFDKSIINITQSWPN---------------------ESDPDKSLNFVQRNE------ELLKHFG--MLGRWDDSQRFLAEYHHLICEETANYLILWCFRLQAEKKEALMEQVAHQAVVMQFILEMARNTQQ------DPRGCFRHFFQKAKAGQ------EGYLDVFHTELQAFKDRVKEYTMKSTGETPKDTVHQN-------------------TPPACCLDPKEVFES-LPQELKTCIQMQDMQILQNVLSSMNPQVAEYHVKRCLEAGLWTNIPRTSKDESSEVDEWKMMET------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24276-1", "uniprot_id": "CDC37_DROME", "id": "Q24276-1", "name": "Hsp90 co-chaperone Cdc37", "aln": "----------MVDYSKWKNIEISDD-EDDTHPNIDTPSLFRWRHQARVERMAEMDHEKDELKKKRQSYQARLMDVKERISKKD----------------------------------------GDE-EALKKELEKIEAEGKELDRIESEMIKKE-------KKTPWNVDTISKP------------GFEKTVINKKAGRKPDENLS---------------EEEREQRMKQFVKENE------KLCQQYG--MLRKYDDSKRFLQEHLHLVGEETANYLVIWSINLEMEEKHELMAHVAHQCICMQYILELAKQLDV------DPRACVSSFFSKIQHCH------PEYRAQFDSEIEGFKGRIQKRAQEKIQEAIAQAEEEERKE----------------RLGPGGLDPADVFES-LPDELKACFESRDVELLQKTIAAMPVDVAKLHMKRCVDSGLWVPNAADLEGDKKEEDDSDDVAGGEEKTDDAKSESAAKEEPIYTGVSTEDVD-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P06101-1", "uniprot_id": "CDC37_YEAST", "id": "P06101-1", "name": "Hsp90 co-chaperone Cdc37", "aln": "---------MAIDYSKWDKIELSDDSDVEVHPNVDKKSFIKWKQQSIHEQRFKRNQDIKNLETQVDMYSHLNKRVDRILSNLPESSLTDLPAVTKFLNANFDKMEKSKGENVDPEIATYNEMVEDLFEQLAKDLDKEGKDSKSPSLIRDAILKHRAKIDSVTVEAKKKLDELYKEKNAHISSEDIHTGFDSSFMNKQKGGAKPLEATPSEALSSAAESNILNKLAKSSVPQTFIDFKDDPMKLAKETEEFGKISINEYSKSQKFLLEHLPIISEQQKDALMMKAFEYQLHGDDKMTLQVIHQSELMAYIKEIYDMKKIPYLNPMELSNVINMFFEKVIFNKDKPMGKESFLRSVQEKFLHIQKRSKILQQEEMDESNAEGVETIQLKSLDDSTELEVNLPDFNSKDPEEMKKVKVFKTLIPEKMQEAIMTKNLDNINKVFEDIPIEEAEKLLEVFNDIDIIGIKAILEN----EKDFQSLKDQYEQDHEDATMENLSLNDRDGGGDNHEEVKHTADTVD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .. . . .. : . * : :: : .. . :. : *:.:.:* . *:. : : ..:* : .:..*::** :: :: *: . *:: .:. : . . : :: **. * :* *: . : . **.* . : .. :: :: * : . :: : :. :*:: . :: : . : * * ", "identical_positions": 22, "similar_positions": 87, "identity": "4.24%" }, { "cls_id": "homologset.agr.RGD:1309296", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LKZ7-1", "uniprot_id": "A0ABK0LKZ7_RAT", "id": "A0ABK0LKZ7-1", "name": "", "aln": "-----MAAGGAAGLREEQRYGLACG-RLGQDNITVLHVKLTETAIRALETYQSQKSLIPFQP----SIQFQGLQGLMKIPK-NDPFNEVHNFNFYLSNVG-------------KDNPQGSFDCIQQTLSSSGASQLNCLGFIQDKITVCATNDSYQMTRERMTQAEEESRNRSTKVIKPGGPYVGKRVQIRKAPQAISDAVPERKRSTPMNPANTIRKMHGGSS----------------------------------------------------------------------------------------------------------------------------------------------------------VSQRPYRDRVIHLLALKAYKKPELLARLQKDGVNQKDKNSLGAILQQVANLNPKDLSYTLKDYVFKELQRDWPGYSETDKQTLDLVLSRKLNP--SQNAG-TSRPESPMCSSKDAASSPQKR--------------------PLDSDFIDPLTNKKARISHLTNRVPPTLNGHLNP-------TNEKSCASLLPPP---------------------------AAAAIPTPSPLPSTHLPVSNPTQTVNSNSNSPSTPEGRGTQDLP--VDSFSQNSSIFEDQQDKYTSRTCLEETLPSSSALLKCPKPMEEEHPVSHKKSKKKSKKHKE------------------------------------------------------------------KDQIKKHDIESREEKEKDLQREE-----TAKLSNDSPNPNEGVKEECTASMEPSSTIELPDYLIKYIAIVSYEQRQNYKDDFNAEYDEYRALHARMETVARRFIKLDAQRK---RLSPGSKEYQNVHEEVLQEYQKIKQSSPNYHEEKYRCEYLHNKLAHIKRLIVDVCNHK-------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UKU1-1", "uniprot_id": "ELL2_MOUSE", "id": "Q3UKU1-1", "name": "RNA polymerase II elongation factor ELL2", "aln": "-----MAAGGAAGLREEQRYGLACG-RLGQDNITVLHVKLTETAIRALETYQSHKNLIPFRP----SIQFQGLQGLMKIPK-NDPFNEVQNFNFYLSNVG-------------RDNPQGSFDCIQQTLSSSGASQLNCLGFIQDKITVCATNDSYQMTRERMTQAEEESRNRSTKVIKPGGPYVGKRVQIRKAPQAISDTVPERKRSTPMNPANTIRKMHSGNS----------------------------------------------------------------------------------------------------------------------------------------------------------VSQRPYRDRVIHLLALKAYKKPELLARLQKDGVNQKDKNSLGAILQQVANLNPKDLSYTLKDYVFKELQRDWPGYSETDRQTLDLVLSRKLNP--SQNAS-TSRSESPLCSSKDAASSPQKR--------------------PLDSDFIDPLMNKKARISHLTNRVPPTLNGYLNP-------TSEKSCAGLLPPP---------------------------AAAAIPTLSPLPSTHLPVSNPPQTVNSNSNSPSTPEGLGTQDLP--VDSFSQNGSIFEDQQEKYTSRTCLET-LPPSSALLKCPKPMEEEHPVSHKKSKKKSKKHKE------------------------------------------------------------------KDQIKKLDIETMEEKEEDLQREE-----TAKLSNASPNPNEGVKEGCTASMEPSSALELPDYLIKYIAIVSYEQRQNYKDDFNAEYDEYRALHARMETVARRFIKLDAQRK---RLSPGSKEYQNVHEEVLQEYQKIKQSSPNYHEEKYRCEYLHNKLAHIKRLIGEFDQQQAESWH--------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00472-1", "uniprot_id": "ELL2_HUMAN", "id": "O00472-1", "name": "RNA polymerase II elongation factor ELL2", "aln": "-----MAAGGTGGLREEQRYGLSCG-RLGQDNITVLHVKLTETAIRALETYQSHKNLIPFRP----SIQFQGLHGLVKIPK-NDPLNEVHNFNFYLSNVG-------------KDNPQGSFDCIQQTFSSSGASQLNCLGFIQDKITVCATNDSYQMTRERMTQAEEESRNRSTKVIKPGGPYVGKRVQIRKAPQAVSDTVPERKRSTPMNPANTIRKTHSSST----------------------------------------------------------------------------------------------------------------------------------------------------------ISQRPYRDRVIHLLALKAYKKPELLARLQKDGVNQKDKNSLGAILQQVANLNSKDLSYTLKDYVFKELQRDWPGYSEIDRRSLESVLSRKLNP--SQNAAGTSRSESPVCSSRDAVSSPQKR--------------------LLDSEFIDPLMNKKARISHLTNRVPPTLNGHLNP-------TSEKSAAGLPLPP---------------------------AAAAIPTPPPLPSTYLPISHPPQIVNSNSNSPSTPEGRGTQDLP--VDSFSQNDSIYEDQQDKYTSRTSLET-LPPGSVLLKCPKPMEENHSMSHKKSKKKSKKHKE------------------------------------------------------------------KDQIKKHDIETIEEKEEDLKREEE----IAKLNNSSPNSSGGVKEDCTASMEP-SAIELPDYLIKYIAIVSYEQRQNYKDDFNAEYDEYRALHARMETVARRFIKLDAQRK---RLSPGSKEYQNVHEEVLQEYQKIKQSSPNYHEEKYRCEYLHNKLAHIKRLIGEFDQQQAESWS--------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VW51-1", "uniprot_id": "ELL_DROME", "id": "Q9VW51-1", "name": "RNA polymerase II elongation factor Ell", "aln": "MTNSIASTKCLPNALSTGNYGMSQSHRYTDDSKEYIIVKLTDSAFRAIEEYQRDDNAKRLQPGQRAKIQFVGNTGVIQFPRPATDANGIPNANGNGSDATGAGGGGGRKFGFTINNMEGTLECVQQQQRS-----LGVLGAVTLRMRIHANEDVYDSTRTKMAIAEETEKSKCIREIKPNQSDIGRKVKKPPSAIQSSASTASAFSSNSSNSGLTTTAFHHHSNSNNSGNNNNRSSSSSNSFNSNNHSRKLGSSPFNGLGVGSSSSSSAFASRSPNPSTLGAIGTVNGSGVVGGRYGGGAASSLASTFANGISQGYHNLSGSSPRDSMTAGTSSATASSVISSRNKMPSGGLTSSNSNSSSSSRSANSKSSGGNKMSDVSRRNIRERLIHLLALKAFKKPELFARLKNEGIRDRERNQITNILMDISTMSHN--TYNLRRQMWNDVDENWPFFSEQEVQQLKRRKPQNLTPPMSSDAGSSTSGQSPTSTHTGSPPPPSSNGGPGGVGSGAGGTSMKRTSLEYDETMFSTVQPKKQRISHYKKDTPPSGTSYSSAGVSMSLGSSGSSSRSRYTPPQRQPGPLDDHSTTDLSYNVLDNIVEFMSSTAAATQQSMEQQQHPRSNSSNNRRGSSSLAGTSNGGNNKDKRNSTGSNSSSSSGYETQQDRQRSTTPMSSNRSSASSSTTPPKLAASFVPAATSGSASGTSKQRMPPQQSDYNSYNSNNAQHVASNSKKRMGSVGPSGGSNGQRQRSASGSNSGYQQVPPPSSNSRSSIQQQNQHQKQQVQQKQAPSQQQQQQQQQYHQQAKHPSPSQQLAAAAHAYAHATADTDSSATPRYDFSQYVPIQTLEVRRRYKTEFESDYDEYRKLLTRVEDVRNRFQDLSERLESARRCDNGYGDYDHIKRQIVCEYERINNDR-TIGEDKERFDYLHAKLAHIKQLVMDYDKTLMSATMAMAPTDVVAAQGPDPAVAKAAARLAEHHRRQHHAAETIKQQQQQKQTHQHHLQRHLQHHLQQQQNLLQQQQNLLQQQSVSNSDDSSDSSDSNDDDDDDDEDCDDSNSNTDDDEARY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: . . .**:: . * :*. : ****::*:**:* ** ... ::* .*** * *::::*: * : * * *:. :* :*:::*:** * *. ** : :: : *.:* *: ** :*: *** .:.:. : ***. . :*::*: :. * :... *.. *.. * * .. :*:* *:*:********:*****:***:::*:.::::*.: ** :::.:. : :*.*: ::::::.:** :** : : *. .::*.* *.:*. :: :** .: .: ..*... *. ::..: ** **** .: .**: ..: .. :. .*. . ** :::* .* .: . * *:..: ...*. ..*.:* ..:* ..* *...* :* **:: * * :. ...* . ** . . : . * . :.*:: ::* :* ::: : .:: :::: ** . * : ..: . *: :. *: : :*:.* : * *:.** :*:::***** * :*:* * .** .*. : : * . * :*::::.::: **::*::. . *:* * :*** ******:*: : : ", "identical_positions": 169, "similar_positions": 256, "identity": "15.84%" }, { "cls_id": "homologset.agr.RGD:1309297", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q86TS9-1", "uniprot_id": "RM52_HUMAN", "id": "Q86TS9-1", "name": "Large ribosomal subunit protein mL52", "aln": "MAALGTVLFTGVRRLHCSVAAWAGGQWRLQQGLAANPSGYGPLTELPDWSYADGRPAPPMKGQLRRKAERETFARRVVLLSQEMDAGLQAWQLRQQKLQEEQRKQENALKPKGASLKSPLPSQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LDF4-1", "uniprot_id": "A0ABK0LDF4_RAT", "id": "A0ABK0LDF4-1", "name": "Large ribosomal subunit protein mL52", "aln": "MAALGTWLSS-VRRLHSSAVARAGSQWRLQQGLAANPSGYGPLTELPDWSFADGRPAPPMKGQLRREAQREKLARRVVLLTQEMDAGLQAWKLRQQKLQEE-RKQKHDLKPKGTSLRNPLPNQ", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****** * : *****.*..* **.*************************:***************:*:**.:*******:**********:********* ***:: *****:**:.***.*", "identical_positions": 99, "similar_positions": 18, "identity": "80.49%" }, { "cls_id": "homologset.agr.RGD:1309299", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P0C1T0-1", "uniprot_id": "MMEL1_RAT", "id": "P0C1T0-1", "name": "Membrane metallo-endopeptidase-like 1", "aln": "--------------------------------------------------------------------MGKSESSVGMMERADNCGRRRLGFVECG------------------LLVLLTLLLMGAIVTLGVFYS--IGKQLPLLNSLLHVSRHERTVVKRVLR---DSSQKSDICTTPSCVIAAARILQNMDQSKKPCDNFYQYACGGWLRHHVIPETNSRYSVFDILRDELEVILKGVLEDSSVQ-HRPAVEKAKTLYRSCMNQSVIEKRDSEPLLNVLDMIGGWPVAMDKWNETMGPKWELERQLAVLNSQFNRRVLIDLFIWNDDQNSSRHVIYIDQPTLGMPSREYYFKEDS-HRVREAYLQFMTSVATMLRRDLNLPGETDLVQEEMAQVLHLETHLANATVPQEKRHDVTALYHRMGLEELQERFGLKGFNWTLFIQNVLSSVQVELLPNEEVVVYGIPYLENLEEIIDVFPAQTLQNYLVWRLVLDRIGSLSQRFKEARVDYRKALYGTTMEEVRWRECVSYVNSNMESAVGSLYIKRAFSKDSKSIVSELIEKIRSVFVDNLDELNWMDEESKKKAQEKALNIREQIGYPDYILEDNNRHLDEEYSSLTFSEDLYFENGLQNLKNNAQRSLKKLREKVDQNLWIIGAAVVNAFYSPNRNLIVFPAGILQPPFFSKDQPQALNFGGIGMVIGHEITHGFDDNGRNFDKNGNMLDWWSNFSARHFRQQSQCMIYQYSNFSWELADNQNVNGFSTLGENIADNGGVRQAYKAYLQWLAEGGRDQRLPGLNLTYAQLFFINYAQVWCGSYRPEFAIQSIKTDVHSPLNAQVLGSLQNLPGFSEAFHCPRGSPMHPMNRCRIW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JLI3-1", "uniprot_id": "MMEL1_MOUSE", "id": "Q9JLI3-1", "name": "Membrane metallo-endopeptidase-like 1", "aln": "-----------------------------------------------------------------------------MVERAGWCRKKSPGFVEYG------------------LMVLL-LLLLGAIVTLGVFYS--IGKQLPLLTSLLHFSWDERTVVKRALR---DSSLKSDICTTPSCVIAAARILENMDQSRNPCENFYQYACGGWLRHHVIPETNSRYSVFDILRDELEVILKGVLEDSTSQ-HRPAVEKAKTLYRSCMNQSVIEKRDSEPLLSVLKMVGGWPVAMDKWNETMGLKWELERQLAVLNSQFNRRVLIDLFIWNDDQNSSRHVIYIDQPTLGMPSREYYFQEDNNHKVRKAYLEFMTSVATMLRKDQNLSKESAMVREEMAEVLELETHLANATVPQEKRHDVTALYHRMDLMELQERFGLKGFNWTLFIQNVLSSVEVELFPDEEVVVYGIPYLENLEDIIDSYSARTMQNYLVWRLVLDRIGSLSQRFKEARVDYRKALYGTTVEEVRWRECVSYVNSNMESAVGSLYIKRAFSKDSKSTVRELIEKIRSVFVDNLDELNWMDEESKKKAQEKAMNIREQIGYPDYILEDNNKHLDEEYSSLTFYEDLYFENGLQNLKNNAQRSLKKLREKVDQNLWIIGAAVVNAFYSPNRNQIVFPAGILQPPFFSKDQPQSLNFGGIGMVIGHEITHGFDDNGRNFDKNGNMLDWWSNFSARHFQQQSQCMIYQYGNFSWELADNQNVNGFSTLGENIADNGGVRQAYKAYLRWLADGGKDQRLPGLNLTYAQLFFINYAQVWCGSYRPEFAVQSIKTDVHSPLKYRVLGSLQNLPGFSEAFHCPRGSPMHPMKRCRIW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q495T6-1", "uniprot_id": "MMEL1_HUMAN", "id": "Q495T6-1", "name": "Membrane metallo-endopeptidase-like 1", "aln": "--------------------------------------------------------------------MGKSEGPVGMVESAGRAGQKRPGFLEGG------------------LLLLL-LLVTAALVALGVLYADRRGKQLPRLASRLCFLQEERTFVKRKPRGIPEAQEVSEVCTTPGCVIAAARILQNMDPTTEPCDDFYQFACGGWLRRHVIPETNSRYSIFDVLRDELEVILKAVLENSTAK-DRPAVEKARTLYRSCMNQSVIEKRGSQPLLDILEVVGGWPVAMDRWNETVGLEWELERQLALMNSQFNRRVLIDLFIWNDDQNSSRHIIYIDQPTLGMPSREYYFNGGSNRKVREAYLQFMVSVATLLREDANLPRDSCLVQEDMVQVLELETQLAKATVPQEERHDVIALYHRMGLEELQSQFGLKGFNWTLFIQTVLSSVKIKLLPDEEVVVYGIPYLQNLENIIDTYSARTIQNYLVWRLVLDRIGSLSQRFKDTRVNYRKALFGTMVEEVRWRECVGYVNSNMENAVGSLYVREAFPGDSKSMVRELIDKVRTVFVETLDELGWMDEESKKKAQEKAMSIREQIGHPDYILEEMNRRLDEEYSNLNFSEDLYFENSLQNLKVGAQRSLRKLREKVDPNLWIIGAAVVNAFYSPNRNQIVFPAGILQPPFFSKEQPQALNFGGIGMVIGHEITHGFDDNGRNFDKNGNMMDWWSNFSTQHFREQSECMIYQYGNYSWDLADEQNVNGFNTLGENIADNGGVRQAYKAYLKWMAEGGKDQQLPGLDLTHEQLFFINYAQVWCGSYRPEFAIQSIKTDVHSPLKYRVLGSLQNLAAFADTFHCARGTPMHPKERCRVW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A140LH71-1", "uniprot_id": "A0A140LH71_DANRE", "id": "A0A140LH71-1", "name": "", "aln": "--------------------------------------------------------------------MGKSESQMDIMEKSTKPRKHRWTVVEIG------------------LSVIV-LLMSCALAGLIVLYT-------SALRERFNINDSSKGLKYR-------SDADSNVCTTPQCVTAAARLLQNMDPSVDPCQNFYQYACGGWIERHVIPETSSLHSVFNILRDELEIVLKGVLEMENKD-DREAFKKAKTLYSSCMNEILIEQRDSQPLLRLIDSIGDWPVASEVWNGTSEQTWSLEDTLAVLNGRYNKKAVLEMFVWPDDRDSSRYIIHVDQPALGMPSRDYYLSDGNYKKVREAYLEFMVSMARIAREDRNLTQDEERVLEDMSQVLELETDIANATSPAEERNDITVLYNKMTLREAQQTFNLNGFNWTRYIQGIMSSVSISVQSDEPIVIYCSPYLEKLSEVLSKHSHRTLQNYLVWMLIMDRVSSMSRRFKDVRAHYRKALHGTTVEEARWRDCVRYVQGNMENAVGALYVRETFSGNSKRMVGELIKKIQEAYVETLEELSWMDEQSKVKAREKAMAISEQIGYPDHILEEENKKLDQEYAHLNFSEENYFENILENLAASAQKGHKKLREPVDPDMWIIGAAVVNAFYSHNRNQIVFPAGILQPPFFSEKQLQALNFGGIGMVIGHEITHGFDDHGRNFDKDGNMYNWWSNYSAERFEDQSKCMVEQYGRFSWKLAGGQNVSGITTLGENIADNGGVRQAYKAYVKWVEREGEEPRLPGLDMNHKQLFFLNFAQVWCGACRPEYAIQTIKTDPHSPLEYRVLGSLQNFEAFSEAFHCARGAPMNPEEKCRVW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W436-1", "uniprot_id": "NEP_DROME", "id": "Q9W436-1", "name": "Neprilysin-1", "aln": "MSQQHEATAAAAEKPLNNGYLQANAPLEELSATVVSPLLGQQQVQHQAPHQMQQQQQQQQQNKLPTVVFLAPDGSGGVGIQRGNPAQGNPGMVTGTGSHSDWLLKESQQRRRLLVLAIAFTVLGAAIGALAIYFAS---VHQRCHLYRLEPDNDDRPNGRWNQDSGSAHEGQDNICMTQECVRTAASLLSAMDLNSDPCEDFFQYACGTWNKMHPIPEDRSSISTFEVLSDQQQVILRAVLEEPIDERDNKATIKAKTFFKSCMDIPQIRKIGTGRLKQVLQSLGGWPVIERNWSPPADLS--VERLMGQLRLNYSEPVMIELYVGADDKNSSVNILQMDQLQYALPSRDYYLKESS-ANDRRAYHRYMTQVALLLG------ADPATAAAELEKVVLFETQLVNVSLPEADRHDTSLVYRKMLLPELQELV--PEVQWQEYLQAALG-PGIPLQEDEPLVTYGLHYLTEMGKILAHTDRRVVHNYMLWRLVMSLMSHMIDEYQRERVEFRKILMGIQSERTRWSQCVEWTNKKLGVAVGALFIRDNFNQESKEVALEMIHTIRAAFNELLAENDWMDDETRAVAKEKADSMNERIGYPELLTN--ATELEQEYVNLTIVPDNFINNVLSILQWESEKMLRLLRQPVDKEKWTTEPAVVNAFYNPNKNDIVFPAGILQPLFYSQHFPKSLNYGGIGVVIGHEITHGFDDKGRQFDKEGNMMQWWNNATIEAFRERTQCVIDQYSRYKINEVD-MFMDGRMTQGENIADNGGLKQAFRAYKKWETLHGREQQLPGLNMTHDQLFFLNYAQIWCGSMRPEDALTKIRSAVHSPGFVRVLGPLSNSRDFASAYKCPLGSTMNPAEKCSVW", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : .: : : :: *: * : :: : .: . .::* * ** :** :*. ** . .**::*:*:*** * . * *** * * *::* *: :::*:.*** . .. * **:*:: ***: *.: .: * ::. :*.*** *. . :* :. :. .:.. .:::::: **::** :: :** .:***:**:. .. . *.** .:*..:* : : . :: :*: :**.:.:.: * .*:* :*.:* * * *. . .:* ::* :. : : :* :* * ** :: .:: :.::**::* *::. :. : .:: *..:** * * *..** :** :.: :: ***:*::: * :** . *:*..:: .: : * * .***:::: *:*** : *:**:*: : : .*::** *.: : :::* *. * ::: : **: ** : * .*******. *:* ********** *:*:. ::**:****:************:**:***:*** :**.* : . *.::::*:: **..:. . .. :.* * *********::**::** :* *.: :****::.: ****:*:**:***: *** *: .*:: *** :***.*.* *:.:::*. *:.*:* ::* :*", "identical_positions": 234, "similar_positions": 262, "identity": "26.99%" }, { "cls_id": "homologset.agr.RGD:1309302", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZJQ8-1", "uniprot_id": "D3ZJQ8_RAT", "id": "D3ZJQ8-1", "name": "", "aln": "MSVHRCCQVQSPKPLVSVELPSRYRSCPPDCNFLCSVCHGVLKRPMRLPCSHIFCKKCIFQWLARQNTCPCCRKEVKRRKMVQVNKLRKTIGRLQVKCKNAAAGCLVTCPLAHRKGHQDSCPFELMACPNEGCTAQVLRGVLDEHRQHCQQNGQQRCPLGCGATLAALEGEQHNCYRELRDAWVQRHERNRTLLLNLLGRVRRVYRTTNLIRRQLAQLSNFLEDD-TLLLN--ARVQETEVAPE----PEMWGAQGQGVL--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQ29-1", "uniprot_id": "RN151_MOUSE", "id": "Q9CQ29-1", "name": "RING finger protein 151", "aln": "---------------MSGGYDLNLFASPPDCKFLCSVCHGVLKRPTRLPCSHIFCKKCIFRWLARQNTCPCCRKEVTRRKMVEVNKLRKTIGRLQVKCKNAAAGCLDTHPLAHRKEHQDSCPFELMACPNEGCTVQVLRGVLDEHRQHCQQNGQQRCPLGCGSTLAALEGEHHNCYRELRDAWVQRHERNRTLLLGLLGRVRRVHLTTSIIHQQLAQLSNFLEDDDNLLLN--AQVQETEVTPE----AEMRGTQGQSVL--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q2KHN1-1", "uniprot_id": "RN151_HUMAN", "id": "Q2KHN1-1", "name": "RING finger protein 151", "aln": "---------------MGGGYDLNLFASPPDSNFVCSVCHGVLKRPARLPCSHIFCKKCILRWLARQKTCPCCRKEVKRKKVVHMNKLRKTIGRLEVKCKNADAGCIVTCPLAHRKGHQDSCPFELTACPNEGCTSQVPRGTLAEHRQHCQQGSQQRCPLGCGATLDPAERARHNCYRELHNAWSVRQERRRPLLLSLLRRVRWLDQATSVVRRELAELSNFLEEDTALLEG--APQEEAEAAPEGNVGAEVVGEPRANIPCK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q0M8-1", "uniprot_id": "A0A8M9Q0M8_DANRE", "id": "A0A8M9Q0M8-1", "name": "", "aln": "---------------MTGGYEVDQFVDPPDDDLICVICRAVLRCPVRLKCNHVFCKECILQWMKRQVKCPCCRQSIDQNQMLVLFKLSKSIGRLSVKCRNGQQGCRATFPLSNEYLHISTCPYEWQICPHEGCGQQVLRKDVQAHDQSCTHWR-QLCPMGCGTLLVRENQTQHNCYRELQQRYLAERRKQRAIAANLRRKMQRMQSRMAQIKRQINLMCESLEVGDLETEAGEGTSAWTDASPSSSRHRHTYNSRIRFI---", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *** .::* :*:.**: * ** *.*:***:**::*: ** .*****:.: :.::: : ** *:****.***:*. ** * **::. * .:**:* **:*** ** * : * * * : * **:***: * : :*******:: : .:.:.*.: .* ::: : ::::: :.: ** . . ::.:*. . . : ", "identical_positions": 75, "similar_positions": 74, "identity": "28.63%" }, { "cls_id": "homologset.agr.RGD:1309303", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZU86-1", "uniprot_id": "D3ZU86_RAT", "id": "D3ZU86-1", "name": "", "aln": "---------------------------------MLFSLNEWLWQETYWLPPNVTWAQLE-----DRD--GLVFAHPHHVLAALPIALVLVAMRIIFERFVALPLSRWMGVQDPIRRKIKPNPVLEKYFLRMKQR-PVETQMVLLASQCGLTLRQIQRWFRRRRNQDRPCLSKKFCEASWRFVFYLCSFVGGTSILYH-ESWLWTPALCWENYPHQTLNLALSWWYLLELGFYISLLITLPFDIK--RKDFKEQVAHHFVTVGLIVFSYSVNLLRIGSVVLLLHDCSDYLLEGCKMLNYAHFQRGCDTLFIIFSLVFFYTRLVFFPTEVIYTAVFDS-----------IKNSGPFFGYYFFIVLLGMLQILHVYWFCLILRMICSFLRKGQMREDIRS-DVE-ESDSSDDEA-----VSEGP-QLKNGMARGSRA--AITNGPRSRAAACLTNGHTRAT-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D6J1-1", "uniprot_id": "CERS4_MOUSE", "id": "Q9D6J1-1", "name": "Ceramide synthase 4", "aln": "---------------------------------MSFSLSEWLWQETYWLPPNVTWAELE-----DRD--GLVFAHPHHVLAAFPVALVLVAVRIVFERFVALPLSRWMGVQDPIRRKIKPNPVLEKYFLRMKQC-PEETQMVLLASQCGLTLRQTQRWFRRRRNQDRPSLSKKFCEACWRFVFYLCSFVGGTSILYH-ESWLWSPSLCWENYPHQTLNLSLYWWYLLELGFYLSLLITLPFDVK--RKDFKEQVVHHFVAVGLIGFSYSVNLLRIGAVVLLLHDCSDYLLEGCKILNYAHFRRGCDALFIMFALVFFYTRLIFFPTQVIYTSVYDS-----------IKNSGPFFGYYFFIVLLVMLQILHVYWFCLILRMLYSFLHKGQMTEDIRS-DVE-EPDSSDDEP-----VSEGP-QLKNGMARGSRV--AVTNGPRSRAAACLTNGHTRAT-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HA82-1", "uniprot_id": "CERS4_HUMAN", "id": "Q9HA82-1", "name": "Ceramide synthase 4", "aln": "---------------------------------MLSSFNEWFWQDRFWLPPNVTWTELE-----DRD--GRVYPHPQDLLAALPLALVLLAMRLAFERFIGLPLSRWLGVRDQTRRQVKPNATLEKHFLTEGHR-PKEPQLSLLAAQCGLTLQQTQRWFRRRRNQDRPQLTKKFCEASWRFLFYLSSFVGGLSVLYH-ESWLWAPVMCWDRYPNQTLKPSLYWWYLLELGFYLSLLIRLPFDVK--RKDFKEQVIHHFVAVILMTFSYSANLLRIGSLVLLLHDSSDYLLEACKMVNYMQYQQVCDALFLIFSFVFFYTRLVLFPTQILYTTYYES-----------ISNRGPFFGYYFFNGLLMLLQLLHVFWSCLILRMLYSFMKKGQMEKDIRS-DVE-ESDSSEEAA-----AAQEPLQLKNGAAGGPRP--APTDGPRSRVAGRLTNRHTTAT-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TEC1-1", "uniprot_id": "A0AB32TEC1_DANRE", "id": "A0AB32TEC1-1", "name": "", "aln": "----------------------MCIPLINGFMQLEDNINRWLWREDFWLPPGVTWKDIA-----EGTSDGSRHPVPRDLLISFPLALGFIALRFVFERVVALPLSRRLGVRDRVRLHITPIPKLEAFYLQKKKTEPSQEDLQALVKLCGLSERQIQSWLRRRRIQDRPANSRKFSEASWRFGFYLIIFSAGLISLIH-TPWFWDHRECWSGYPAQAVAEAQYWYYIIELSFYLSLLLCVSVDIK--RKDFQEQIIHHIATIFLIAFSYCANYVRVGTLVMLVHDSSDFLLESAKMFNYAGWRKTCDALFVVFAAVFLVTRLIVFPFRIVYTAVVDS-----------LDVFSPYPGYYFFNGLLLVLQALHIFWAWLILRMVHKFVFLGKVERDERS-DDESEPDEDDEVG---EEEEERSWEHKKGALNSKLA--SLAN---NCVLNNLTNQRQKMNSRTLKER", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2BAR8-1", "uniprot_id": "A0A8M2BAR8_DANRE", "id": "A0A8M2BAR8-1", "name": "", "aln": "----------------------------------MDALSRWFWKQEFWLPPGIVWEDLE-----EMQ--GSRRPMPRDLLLALPLALAFIMLRYAFERRVAFPLSRVLGVKDPVRLKVTPSPSLEAFYT-KNSRQPTQIEISGLVKQCGLTHRQVETWFRNRRNLDRPSNTTKFCEACWRFAFYLVAFTAGLLSLIN-TAWFWDQRECWRGFPRQPLQELHYWYYMLELSFYWSLLLCVSVDVK--RKDFKEQIIHHFATIFLLGFSYCSNYIRIGTLVMLVHDASDFLLESAKMFNYAGWKKTCDSLFVIFAAVFLVTRLLVFPSKIIYTTLVLS-----------MEVFEPFLGYYFFNALLLVLQALHIYWAYLILRMVYKFLFLGKLDKDERS-DVETEPEEEEEEEKEEEEEEQRSWRKRKVVLDSRRA--MLSS---SCVLNNLTQQKADAQ-RRPKAR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W423-1", "uniprot_id": "Q9W423_DROME", "id": "Q9W423-1", "name": "", "aln": "-------------------------------MDILNEFSNVFWSTHIWLPPNTTWADIA-----PGSRPDVVHANYKDLIWPIPFAAVVMLVRYTLERFWISPVGKSLGIRSSRPKKAANVPILEKTYAKSTRL--DKKKLVPLSKQTDMSEREIERWWRLRRAQDKPSTLVKFCENTWRCIYYLYSFIFGVIVLWD-KPWFWDVKSCWYGYPHQSISNDIWWYYMISMSFYWSLTGTQFFDVK--RKDFWQMFIHHMVTLLLMSLSWVCNLHRVGSLVLVVHDCADIFLEAAKLTKYAKYQKLCDAIFAIFTVVWIVTRLGFYP-RIIYSSSVEA-----------PRILPMFPAYYIFNSLLLMLLVLHVIWTYMILKIVVDSLQKGLMSGDIRSSDSEDLTDSSGNAR-----LTNGSARSKNKSISSAPSDKGSAGGAGSRAGARVATTERREE-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38703-1", "uniprot_id": "LAG1_YEAST", "id": "P38703-1", "name": "Ceramide synthase LAG1", "aln": "-MTSATDKSIDRLVVNAKTRRRNSSVGKIDLGDTVPGFAAMPESAASKNEAKKRMKALTGDSKKDSDLLWKVWFSYREMNYRHSWLTPFFILVCVYSAYFLSGNRTESNPLHMFVAISYQVDGTDSYAKGIKDLSFVFFYMIFFTFLREFLMDVVIRPFTVYLNVTSEHRQKRMLEQMYAIFYCGVSGPFGLYIMYHSDLWLFKTKPMYRTYPVITNPFLFKIFYLGQAAFWAQQACVLVLQLEKPRKDYKELVFHHIVTLLLIWSSYVFHFTKMGLAIYITMDVSDFFLSLSKTLNYLNS-VFTPFVFGLFVFFWIYLR-HVVNIRILWSVLTEFRHEGNYVLNFATQQYKCWISLPIVFVLIAALQLVNLYWLFLILRILYRLIWQG-IQKDERS---DSDSDESAE--------------------------------------NEESKEKCE---------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P28496-1", "uniprot_id": "LAC1_YEAST", "id": "P28496-1", "name": "Ceramide synthase LAC1", "aln": "MSTIKPSPSNNNLKVRSRPRRK-SSIGKIDLGDTVPSLGTMFETKESKTAAKRRMQRLSEATKNDSDLVKKIWFSFREISYRHAWIAPLMILIAVYSAYFTSGNTTKTNVLHRFVAVSYQIGDTNAYGKGINDLCFVFYYMIFFTFLREFLMDVVIRPFAIRLHVTSKHRIKRIMEQMYAIFYTGVSGPFGIYCMYHSDLWFFNTKAMYRTYPDFTNPFLFKVFYLGQAAFWAQQACILVLQLEKPRKDHNELTFHHIVTLLLIWSSYVFHFTKMGLPIYITMDVSDFLLSFSKTLNYLDS-GLAFFSFAIFVVAWIYLR-HYINLKILWSVLTQFRTEGNYVLNFATQQYKCWISLPIVFVLIGALQLVNLYWLFLIFRVLYRILWRG-ILKDDRS---DSESDEESDES--------------------------------STTPTDSTPTKKDI--------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : :.: . .. : . . : : : : :: * : : * : . *:: : :* . :*: . .*: . .::: ***. : **:.:: *: *: : ::* : : * :* :*. .* :* * :* :: * .:::: : . :. *: * ::: * :*:::: : * : * ** : .:.. : : . ", "identical_positions": 30, "similar_positions": 86, "identity": "6.45%" }, { "cls_id": "homologset.agr.RGD:1309304", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q3C2P8-1", "uniprot_id": "SPRE2_RAT", "id": "Q3C2P8-1", "name": "Sprouty-related, EVH1 domain-containing protein 2", "aln": "MTEETHPDDDSYIVRVKAVVMTRDDSSGGWFPQEGGGISRVGVCKVMHP--EGNGRSGFLIHGERQKDKLVVLECYVRKDLVYTKANPTFHHWKVDNRKFGLTFQSPADARAFDRGVRKAIEDLIEGSTTSSSTIHN-----EAELGDDDVFTTATDSSSNSSQKREPNTRTISSPTSCEHRRIYTL----DPYPMDLYHPDQ--RLPRSYPQVTFPEDDEEIVRINPREKIWMTGYEDYRHAPVRGKYLDSTEDADS-YVRFAKGEVPKHEYTYPYVDSSDFGFG--EDPKG---NVIKTQPPR--AKSRRR--KENGERSRCVYCRDMFNHEENRRGHCQDAPDAVRTCIRRVSCMWCADSMLYHCMSDPEGD-YTDPCSCDTSDEKFCLRWMALIALSFLAPCMCCYLPLRACHHCGVMCRCCGGKHKAAA---------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q924S7-1", "uniprot_id": "SPRE2_MOUSE", "id": "Q924S7-1", "name": "Sprouty-related, EVH1 domain-containing protein 2", "aln": "MTEETHPDDDSYIVRVKAVVMTRDDSSGGWFPQEGGGISRVGVCKVMHP--EGNGRSGFLIHGERQKDKLVVLECYVRKDLVYTKANPTFHHWKVDNRKFGLTFQSPADARAFDRGVRKAIEDLIEGSTTSSSTLHN-----EAELGDDDVFTTATDSSSNSSQKREPTTRTISSPTSCEHRKIYTL----DPYPMDHYHPDQ--RLPRSYPQVTFPEDDEEIVRINPREKIWMTGYEDYRHAPVRGKYLDTTEDADS-YVRFAKGEVPKHEYTYPYVDSSDFGFG--EDPKG---SVIKTQPPR--AKSRRR--KENGERSRCVYCRDMFNHEENRRGHCQDAPDAVRTCIRRVSCMWCADSMLYHCMSDPEGD-YTDPCSCDTSDEKFCLRWMALIALSFLAPCMCCYLPLRACHRCGVMCRCCGGKHKAAA---------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z698-1", "uniprot_id": "SPRE2_HUMAN", "id": "Q7Z698-1", "name": "Sprouty-related, EVH1 domain-containing protein 2", "aln": "MTEETHPDDDSYIVRVKAVVMTRDDSSGGWFPQEGGGISRVGVCKVMHP--EGNGRSGFLIHGERQKDKLVVLECYVRKDLVYTKANPTFHHWKVDNRKFGLTFQSPADARAFDRGVRKAIEDLIEGSTTSSSTIHN-----EAELGDDDVFTTATDSSSNSSQKREQPTRTISSPTSCEHRRIYTLGHLHDSYPTDHYHLDQ--PMPRPYRQVSFPDDDEEIVRINPREKIWMTGYEDYRHAPVRGKYPDPSEDADSSYVRFAKGEVPKHDYNYPYVDSSDFGLG--EDPKGRGGSVIKTQPSR--GKSRRR--KEDGERSRCVYCRDMFNHEENRRGHCQDAPDSVRTCIRRVSCMWCADSMLYHCMSDPEGD-YTDPCSCDTSDEKFCLRWMALIALSFLAPCMCCYLPLRACYHCGVMCRCCGGKHKAAA---------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NYK3-1", "uniprot_id": "SPRE2_DANRE", "id": "Q6NYK3-1", "name": "Sprouty-related, EVH1 domain-containing protein 2", "aln": "MIEETHPNDDSYIVRVKAVVMTRDDSSGGWLAQEGGGLSRVGVCKVMPA--ELTGRSDFLIHGERLKDKQVILECFVRKDLIYTKATPTFHHWKVDNKKCGLTFQSPADARAFDRGVRKALEDLTEGSTTSSSTLQN-----EAELGDDDVFTTATDSSSNSSQKKDHSTQLVATSTFYEPHPHRCIL---QYRPPERYTLDQ--KFSRN----LFPFEDEEIVRINPRERWMITGYEDYRYAAVPDKFIQP-EDSDS-YVQISKNDPVKHDYTYPYVPSPDFTQCDLKRPCGGGSTVVSTQPRAFILKGKRR--KEDGERSRCVYCRDMFNHEENRRGQCHDAPDPIRTCIHRVSFMWCADSMLYHCMSDPEGD-YSDPCSCDTSEERFCLRWTALLGLAMLAPCLCCYPPLHGCHRCGVACGCCGGKHKAVG---------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8N7T5I8-1", "uniprot_id": "A0A8N7T5I8_DANRE", "id": "A0A8N7T5I8-1", "name": "Sprouty-related, EVH1 domain-containing protein 2", "aln": "MTEESHPDDDSYIVRVKAVVMTRDESSGGWLAQEGGGLSRVGVCKVVPADLELLGRNGFLIFGERLKDKQMILQCFLKKDLVYTKATPTFHHWRVDNRKCGLSFQSPADARAFDRGVRKAIEDLTEGSTTSSSTLQN-----EAELGDDDVFTNATDSSSNSSQKRETSMQTLAPISFSEPHHCILGHLYDQHRHSDRYYLEQTVPMFQCSRHVRFHEEEEEIVRINPRERSWLTGYEDYRHATTATRTKPLRPDVTDAYVHLAKSEPPKHDYTYSYPLSGDGHVSR-DGKTGIGGGVVTGQPRALTAKWLPRRVEDSRERLRCVYCQNMFSPSENGRGRCQEAPDPVQTCIRRVSFMWCADSLLYHCMSDPEGD-YSDPCSCDASEERFCLRWLALLGLSLLAPCMCCYVPLRACYHCGVACHCCGGKHKATG---------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KG11-1", "uniprot_id": "A0A0B4KG11_DROME", "id": "A0A0B4KG11-1", "name": "", "aln": "---MTEGHESDFLVTVRAQVMTRDESTEGWLPLAGGGLANVSIRKRARLS-PLASGHDYIIYGQRISDQSVILSCVINRDLKYYKVMPTFHHWRAGKQRNGLTFQTAADARAFDKGVLRAYNELIDGLAKSNPTIICPPLTKYDSVGEDDVFMTLDLPVESESLQKIHSSPEGSEKSHKSVSNNSDS----EKLPPPPIHYISTDKTSATTSPPDAPPASAAPSPATAGQIAASENYSYVTLTAVHHDYNYPVVDQPVGAQVLNARRESISALKKRNALEAAQAMAAAQTAAGGGLACRDGGSGKPLHKPNVSDILKKETRLRCRYCHELYSEDFNRRGACEYAPDAFRSGYECISGMGCARCMIYHCMSDAEGETAQHPCDCSASEAGCSKRWLGLAILSLFVPCLWCYPPLRACHLAGIHCGLCGGQHKPHVXHLEARLQGQHDDDPRPRSEFHYHHSEQSIMNSAKRPWGAKQKQSQQSQQSQRHFYNWELSHSLGAPQHQTPPYLMQSTGRKAPQNDYGRLLF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. .:..::* *:* *****:*: **:. ***::.*.: * . .::*.*:* .*: ::*.* :.:** * *. ******:..::: **:**:.*******:** :* ::* :* :.*..*: .:*:**** . . ...* :: : : . : . . .. : .*. :.. * : . . . * . * .. * ** **::::. . * ** *. ***..:: . :* * ** .::******.**: .**.*.:*: . ** .* *:::.**: ** **:.*: .*: * ***:**. ", "identical_positions": 106, "similar_positions": 120, "identity": "20.11%" }, { "cls_id": "homologset.agr.RGD:1309305", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LAK9-1", "uniprot_id": "A0ABK0LAK9_RAT", "id": "A0ABK0LAK9-1", "name": "Zinc transporter ZIP12", "aln": "MCFWTELSVWVVLVSHSFSLASSTETSKALTQDN-SRVGSHSLLEVLRVLSAGDDRSLNHPQSLIKILLERTGCPQRTDGTQEDCKLCLEPDALSLTAGGDLEDELREEVVQRVSLLLLYYIIHQEEICSSKLNMSNREYEFYLHSLLSLRQDEDSYFLSEKETDDILASTRKYFGTSTSPCMETKILQRESGIQSSNGADEKMLPQLAATIIALSLQGVCLGRKDSPSPDDFTEYIFSFLNRTNALHLSELEELLNMLSTRRACTKIN-TLHEHQRKQN-TAVHGLRDPKSAAAMDKVSGDHSVSWDQACFSAQQLVEIFLQNHSSLSISKEDFKQLSPGIIQQLLSCSCQVPRDQKAKPPPTTLEKYGYSTVAVTLLTLGSMLGTALVLFHSCEENYSLILQLFVGLAVGTLSGDALLHLIPQVLGLHKQEA-ELGHFHESQSPIWKLLGLLGGIHGFFLIEKCFILLVSPN-TKGLPLVNGHAGHTHHLGLSPELNDQSGGGKSISTIQLKGPEDSQTAELPKGNVPASNRNRKTISLLAVMVLVGDGLHNFADGLVIGTAFSSSLESGVTTTIAILCHEIPHEMGDFAVLLSSGLSIRTAILMNFLSALTAFIGLYIGLSVSADPRVQDWILTVTAGMFLYLSLVGMGSCFWKGWLYRPLVLELQNLNHLALFLNVETVNLNSGSHACSKSPLPWSMSPESEIWISS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5FWH7-1", "uniprot_id": "S39AC_MOUSE", "id": "Q5FWH7-1", "name": "Zinc transporter ZIP12", "aln": "MCFWTNLSVWMILLSHSLSLVSSTETGKTLTQNN-SRAGSQGLLEVLRVLSAGDHWSLNHPQSLIKILLERTGCPQRTDWTQGDCKLCLEADALLLTAGGNLEDELREEVVQRVSLLLLYYIIHQEEICSSKLNMSNREYEFYLHSLLGLRQDEDSYFLSEKETDDILAFTRKYFGTSSSQCMETKILQRESGIQGSNGADEKTLPQLAATIIALSLQGVCLGRKALPSPDDFTEYIFSFLNSTNTLHLSEIEQLLNMLTTRRTCAKEDKYLHQYQRKQN-TEEHSLRDPKTSTAMDKESDDHSPSWDQACFSARQLVEIFLQNHSSLSISKEDFKQLSPGIIQQLLSCSCQMPKDQQAKPPPTTLEKYGYSTVAVTLLTLGSMLGTALVLFHSCEENYSLILQLFVGLAVGTLSGDALLHLIPQVLGLHKQEA-EFGHFHESQSPIWKLLGLLGGIHGFFLIEKCFILLVSPN-TKGLPLVNEHVGHTHHLGLNPELNDQSSGGKSISTIQLKGPEDSQTTVLPIGNVPASNRNGKTISLLAIMILVGDSLHNFADGLVIGTAFSSSLESGVTTTIAILCHEIPHEMGDFAVLLSSGLSVRTAILMNFLSALTAFAGLYIGLSVSADPRVQDWILTVTAGMFLYLSLVGM----------LPEMTHVQTQRPWMTFL-LQNVGLVLG-----WFSLLLLAVYEQNIKI--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q504Y0-1", "uniprot_id": "S39AC_HUMAN", "id": "Q504Y0-1", "name": "Zinc transporter ZIP12", "aln": "MCFRTKLSVSWVPLFLLLSRVFSTETDKPSAQDSRSRGSSGQPADLLQVLSAGDHPPHNHSRSLIKTLLEKTGCPRRRNGMQGDCNLCFEPDALLLIAGGNFEDQLREEVVQRVSLLLLYYIIHQEEICSSKLNMSNKEYKFYLHSLLSLRQDEDSSFLSQNETEDILAFTRQYFDTSQSQCMETKTLQKKSGIVSSEGANESTLPQLAAMIITLSLQGVCLGQGNLPSPDYFTEYIFSSLNRTNTLRLSELDQLLNTLWTRSTCIKNE-KIHQFQRKQNNIITHDQDYSNFSSSMEKESEDGPVSWDQTCFSARQLVEIFLQKGLSL-ISKEDFKQMSPGIIQQLLSCSCHLPKDQQAKLPPTTLEKYGYSTVAVTLLTLGSMLGTALVLFHSCEENYRLILQLFVGLAVGTLSGDALLHLIPQVLGLHKQEAPEFGHFHESKGHIWKLMGLIGGIHGFFLIEKCFILLVSPNDKQGLSLVNGHVGHSHHLALNSELSDQAGRGKSASTIQLKSPEDSQAAEMPIGSMTASNRKCKAISLLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVLLSSGLSMKTAILMNFISSLTAFMGLYIGLSVSADPCVQDWIFTVTAGMFLYLSLVEM----------LPEMTHVQTQRPWMMFL-LQNFGLILG-----WLSLLLLAIYEQNIKI--", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** *:*** : : :* . ****.*. :*:. ** .* ::*:******. . **.:**** ***:****:* : * **:**:*.*** * ***::**:********************************:**:*******.******* ***::**:**** **:**.** * ***** **::*** .*:**:*. ****** **:*********: **** ******* ** **:*:***:::*** * ** :* * : :*:.***** *. .: :::*:* * * . ****:****:********: ** ********:*************::*:**:** ************************************** ********************************** *:******:. ****:**:******************** .:**.*** *.**:***.*..**.**:. *** ******.*****:: :* *.:.****: *:*****:*:****.********.**:***** *******************************::*******:*:**** ************ *****:************* * * : .:*. . ** ::...* * .* *.:* * ", "identical_positions": 481, "similar_positions": 117, "identity": "67.65%" }, { "cls_id": "homologset.agr.RGD:1309306", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XIN1-1", "uniprot_id": "MDM4_RAT", "id": "Q5XIN1-1", "name": "Protein Mdm4", "aln": "MTSHSTSAQCSASDSACRISSEQINQQVRPKLQLLKILQAAGAQGEVFTMKEVMHYLGQYIMVKQLYDQQEQHLVYCGGDLLGDLLGCQSFSVKDPSPLYDMLRKNLVTSASVNTDAAQTLALAQDHTMDIPSQD--RLKHGATECSNPRKRTEEDDTHTLPTSRRKCRDSRADEDLIEHLSQDETSR--LDLDFEEWDVAGLPWWFLGNLRNNYIPRSNGSTDLQTN-----QDIGTAIVSDTTDDLWFLNETVSEQLGVGVKVEAAN--CEQPSE-VGRTRDKKMVEGG--KDDDLEDSKSLSDDTDVEVTSEDEWQCTECKKFNSPSKRYCFRCWALRKDWYSDCSKLTHSLSTSNITAIPEKK---------DNEGIDVPDCRRTISAPVVRPKDGYLKEEKPR-FDPCNSVEFLDLAHGSESQEIISSTREQTDIFSEQKTETESMEDFQNVLKPCSLCEKRPRDGNIIHGKTSHLTTCFHCARRLKKSGASCPACKKEIQLVIKVFIA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35618-1", "uniprot_id": "MDM4_MOUSE", "id": "O35618-1", "name": "Protein Mdm4", "aln": "MTSHSTSAQCSASDSACRISSEQIS-QVRPKLQLLKILHAAGAQGEVFTMKEVMHYLGQYIMVKQLYDQQEQHMVYCGGDLLGDLLGCQSFSVKDPSPLYDMLRKNLVTSASINTDAAQTLALAQDHTMDFPSQD--RLKHGATEYSNPRKRTEEEDTHTLPTSRHKCRDSRADEDLIEHLSQDETSR--LDLDFEEWDVAGLPWWFLGNLRNNCIPKSNGSTDLQTN-----QDIGTAIVSDTTDDLWFLNETVSEQLGVGIKVEAAN--SEQTSE-VGKTSNKKTVEVG--KDDDLEDSRSLSDDTDVELTSEDEWQCTECKKFNSPSKRYCFRCWALRKDWYSDCSKLTHSLSTSNITAIPEKK---------DNEGIDVPDCRRTISAPVVRPKDGYLKEEKPR-FDPCNSVGFLDLAHSSESQEIISSAREQTDIFSEQKAETESMEDFQNVLKPCSLCEKRPRDGNIIHGKTSHLTTCFHCARRLKKSGASCPACKKEIQLVIKVFIA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15151-1", "uniprot_id": "MDM4_HUMAN", "id": "O15151-1", "name": "Protein Mdm4", "aln": "MTSFSTSAQCSTSDSACRISPGQIN-QVRPKLPLLKILHAAGAQGEMFTVKEVMHYLGQYIMVKQLYDQQEQHMVYCGGDLLGELLGRQSFSVKDPSPLYDMLRKNLVTLATATTDAAQTLALAQDHSMDIPSQD--QLKQSAEESSTSRKRTTEDDIPTLPTSEHKCIHSREDEDLIENLAQDETSR--LDLGFEEWDVAGLPWWFLGNLRSNYTPRSNGSTDLQTN-----QDVGTAIVSDTTDDLWFLNESVSEQLGVGIKVEAAD--TEQTSEEVGKVSDKKVIEVG--KNDDLEDSKSLSDDTDVEVTSEDEWQCTECKKFNSPSKRYCFRCWALRKDWYSDCSKLTHSLSTSDITAIPEK----------ENEGNDVPDCRRTISAPVVRPKDAYIKKENSKLFDPCNSVEFLDLAHSSESQETISSMGEQLDNLSEQRTDTENMEDCQNLLKPCSLCEKRPRDGNIIHGRTGHLVTCFHCARRLKKAGASCPICKKEIQLVIKVFIA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZUW7-1", "uniprot_id": "MDM4_DANRE", "id": "Q7ZUW7-1", "name": "Protein Mdm4", "aln": "MTSLASSSQLPGS---CRTLPGEGT-QVHPRAPLLQILKVAGAQEEVFTLKEVMHYLGQYIMMKQLYDKQRQHIVHCHDDPLGELLEVGSFSVKNPSPVYEMLKRNLVILN--NSDAAKNLSVGKD-SNESPSEDPGQVSSGSINSAQPLIAGSSSTGTTQSCSQRRPRDP--DEDSSDGLPRSACKRPKLDVTLEEWDLSGLPWWFLGNLRSNYTRRSNGSTDIHTNQLSPGQDEDTAIVSDTTDDLWFLNEAESEQVSVEIKEAVLEQGSDGESPHEDEDTGKDSKDDGKMQEEQEEDSQCLSDDTDTEISTQDAWQCSECRKFNTPLQRYCMRCWALRKDWYKDCPRLVHSISVPDIPACSSRPERDEDEEEEDDDGIDMPDCLRTVSDPVVLPSHRVSRN------IPSSSAS---SSKGKGPSQIHHHFQETSEGDSQDTLDMETEYQPEALLEPCKLCRVRPRNGNIIHGRTAHLITCFPCARKLHKFHAPCPGCGQVIQKVIKTFIA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** ::*:* . * ** . : . **:*: **:**:.**** *:**:************:*****:*.**:*:* .* **:** *****:***:*:**::*** .:***:.*::.:* : : **:* ::. .: : : . .. * . *.:: .. *** : *.:. .* **: :****::***********.* :******::** ** .****************: ***:.* :* . : : * .. .*. : * :::: ***:.******.*::::* ***:**:***:* :***:**********.**.:*.**:*..:*.* ..: :::* *:*** **:* *** *.. :: *..*. ::.. ..: * : *:: : *. : : :*:**.**. ***:******:*.** *** ***:*:* *.** * : ** ***.***", "identical_positions": 225, "similar_positions": 145, "identity": "43.77%" }, { "cls_id": "homologset.agr.RGD:1309307", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5M8N4-1", "uniprot_id": "D39U1_MOUSE", "id": "Q5M8N4-1", "name": "Epimerase family protein SDR39U1", "aln": "MRVLVGGGTGFIGTAVTQLLRGRGHEVKLVSRQPGPGRITWSELSESGLPLCDVVINLAGENILNPLRRWNETFQKEVLTSRLDTTHLLAKAITETAHPPQAWILVTGVAYYQPSLTKEYDEDSPGGNFDFFSNLVTKWEAAARLPGESTRQVVVRSGVVLGRGGGAISHMLLPFRLGLGGPIGSGRQFFPWIHIGDLAGILNYALEANHVQGVLNGVAPASTTTNAEFAQALGAALGRPAFIPVPSTVVRAVFG-ERAIMLLEGQKVVPRRTLATGYQYSFPELRAALKDVVA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZYY0-1", "uniprot_id": "D3ZYY0_RAT", "id": "D3ZYY0-1", "name": "", "aln": "-----GGGTGFIGTALTQLLKTKGHEVKLVSRQPGPDRITWTELSRSGLPLCDVVINLAGENILNPLRRWNETFQKEVLTSRLDTTHLLAKAITEAAQPPQAWILVTGVAYYQPSLTEEYDEDSPGGDFDFFSNLVTKWEAAARLPGESTRQVVVRSGVVLGRRGGAIGHMLLPFRLGLGGPIGSGHQFFPWIHISDLAGILNHALEANHVQGVLNGVAPASTTTNADFAQALGAALGRPAFIPVPSAVVQAIFGRERAIMLLEGQKVVPRRTLATGYQYSFPELGAALKDVVT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NRG7-2", "uniprot_id": "D39U1_HUMAN", "id": "Q9NRG7-2", "name": "Epimerase family protein SDR39U1", "aln": "MRVLVGGGTGFIGTALTQLLNARGHEVTLVSRKPGPGRITWDELAASGLPSCDAAVNLAGENILNPLRRWNETFQKEVIGSRLETTQLLAKAITKAPQPPKAWVLVTGVAYYQPSLTAEYDEDSPGGDFDFFSNLVTKWEAAARLPGDSTRQVVVRSGVVLGRGGGAMGHMLLPFRLGLGGPIGSGHQFFPWIHIGDLAGILTHALEANHVHGVLNGVAPSS-ATNAEFAQTLGAALGRRAFIPLPSAVVQAVFGRQRAIMLLEGQKVIPQRTLATGYQYSFPELGAALKEIVA", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **********:****. :****.****:***.**** **: **** **..:**********************: ***:**:*******::.:**:**:************* *********:*******************:*************** ***:.*****************:********.******.:*******:********:* :***:***:******* ****:**:**:*:** :***********:*:************** ****::*:", "identical_positions": 236, "similar_positions": 42, "identity": "80.27%" }, { "cls_id": "homologset.agr.RGD:1309308", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "B2GV24-1", "uniprot_id": "UFL1_RAT", "id": "B2GV24-1", "name": "E3 UFM1-protein ligase 1", "aln": "MADAWEEIRRLAADFQRAQFAESTQRLSERNCIEIVNKLISQKQLEVVHTLDGKEYITPAQISKEMRDELHVRGGRVNIVDLQQVINVDLTHIENRVGDIIKSEKHVQMVLGQLVDENYLDRLSEEVNDKLQESGQVTVSELCKTYDLPGDFLTQALTQR-LGRIINGHLDLDNRGVIFTEAFVARHKARIRGLFSAITRPTAVNSLVSKYGFQEQLLYSVLEELVSTGRLRGTVVGGRQDKAVFVPDIYSRTQSTWVDSFFRQNGYLEFDALSRLGIPDAVNYIKKRYKNTPLLFLKATCVGQGLVDQ-VEASVEEAISSGTWVDVSPLLPSSLSVEDAAMLLQQVMRPFGKHASATVFSDTVVVSEKFINDCTKLFSERMHQKAEKEMKNNPVHLITEEDLKQIS----ILESVNTNKKDKKDERRKKATEGSGSVRGGGGGNAREYKIKKVKKKGR--------KDEDSDDESQSSHAGKKKP-DITFMFQDEIEGCLRKHIPDAPEEFISELAEHLIKPLNKMYLEVVRSVFMSS-TSASGTGRKRTIKDLQEEVSNLYNNIRLFEKGMKYFADDTQTALTKHLLKTVCTDITNLMFNFLASDLMMAVEDPATITSDMRKKILSKLTEETKVALTKLHNSLNEKSIEDFLSCLDSATEACDIMVKKGDKKRERQILFQHRQALADQLKVTEDPALILHLTSVLLFQFSTHSMLHAPGRCVPQIIAFLHNKIPEDQHTLLVKYQGLVVKQLVSQNKKSGQGEDPSSDDLDKEQHDVTNTTRKELQELSLSIKDLVLKPRKSSVTEE-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CCJ3-3", "uniprot_id": "UFL1_MOUSE", "id": "Q8CCJ3-3", "name": "E3 UFM1-protein ligase 1", "aln": "MADAWEEIRRLAADFQRAQFAESTQRLSERNCIEIVNKLISQKQLEVVHTLDGKEYITPAQISKEMRDELHVRGGRVNIVDLQQVINVDLTHIESRVSDIIKSEKHVQMVLGQLIDENYLDQLSEEVNDKLQESGQVTVSELCKAYDLPGDFLTQALTQR-LGRIINGHLDLDNRGVIFTEAFVARHKARIRGLFSAITRPTPVNSLVSKYGFQEQLLYSVLEDLVSTGRLRGTVVGGRQDKAVFVPDIYSRTQSTWVDSFFRQNGYLEFDALSRLGIPDAVNYIKKRYKNTQLLFLKATCVGQGLVDQ-VEASVEEAISSGTWVDISPLLPSSLSVEDAAMLLQQVMRPFGKLASAIVFSDTVVVSEKFITDCTGLFSERMHQKAEKEMKNNPVHLITEEDLKQIS----ILESVNTSKKDKKDERRKKATEGSGSVRGGGGGNAREYKIKKTKKKGR--------KDEDSDDESQSSHGGKKKP-DITFMFQDEIEDCLRKHIQDAPEEFISELAEYLIKPLNKMYLEVVRSVFMSS-TSASGTGRKRTIKDLQEEVSNLYNNIRLFEKGMKYFADDTQTALTKHLLKTVCTDITNLMFNFLASDFLMAVEEPAAITSDIRKKILSKLTEETKVALTKLHNSLNEKSIEDFLSCLDSATEACDIMVKKGDKKRERQILFQHRQALCEQLKVTEDPALILHLTAVLLFQLSTHSMLHAPGRCVPQIIAFLHSKIPEDQHTLLVKYQGLVVKQLVSQNKKTGQGEDPSSDELDKEQHDVTNATRKELQELSLSIKDLVLKSRKSSVTEE-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O94874-1", "uniprot_id": "UFL1_HUMAN", "id": "O94874-1", "name": "E3 UFM1-protein ligase 1", "aln": "MADAWEEIRRLAADFQRAQFAEATQRLSERNCIEIVNKLIAQKQLEVVHTLDGKEYITPAQISKEMRDELHVRGGRVNIVDLQQVINVDLIHIENRIGDIIKSEKHVQLVLGQLIDENYLDRLAEEVNDKLQESGQVTISELCKTYDLPGNFLTQALTQR-LGRIISGHIDLDNRGVIFTEAFVARHKARIRGLFSAITRPTAVNSLISKYGFQEQLLYSVLEELVNSGRLRGTVVGGRQDKAVFVPDIYSRTQSTWVDSFFRQNGYLEFDALSRLGIPDAVSYIKKRYKTTQLLFLKAACVGQGLVDQ-VEASVEEAISSGTWVDIAPLLPTSLSVEDAAILLQQVMRAFSKQASTVVFSDTVVVSEKFINDCTELFRELMHQKAEKEMKNNPVHLITEEDLKQIS----TLESVSTSKKDKKDERRRKATEGSGSMRGGGGGNAREYKIKKVKKKGR--------KDDDSDDESQSSHTGKKKP-EISFMFQDEIEDFLRKHIQDAPEEFISELAEYLIKPLNKTYLEVVRSVFMSSTTSASGTGRKRTIKDLQEEVSNLYNNIRLFEKGMKFFADDTQAALTKHLLKSVCTDITNLIFNFLASDLMMAVDDPAAITSEIRKKILSKLSEETKVALTKLHNSLNEKSIEDFISCLDSAAEACDIMVKRGDKKRERQILFQHRQALAEQLKVTEDPALILHLTSVLLFQFSTHSMLHAPGRCVPQIIAFLNSKIPEDQHALLVKYQGLVVKQLVSQSKKTGQGDYPLNNELDKEQEDVASTTRKELQELSSSIKDLVLKSRKSSVTEE-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PGY6-1", "uniprot_id": "UFL1_DANRE", "id": "Q6PGY6-1", "name": "E3 UFM1-protein ligase 1", "aln": "MAADWEEIRRLAADFQRAQFAETVQRLSERNCIEIVSKLVEDKKLDVVHTLDGKEYVTPAQISREIRDELYMHRGRINVVDLQKIINVDLVHVEGRANEIAKSDRGTQLILGQLIDEAYLDRLAEEVNDKLQEAGQVNIAELCKTYDLPGDFLTEALNAR-LGRVIQGQLDQYNRGMIFTQAFLSRHKACICGLFSGITRPTQINNLLNLYGFQENLVYSMLEELVNSARLKGSVVGGRQDKAIYIPDIYSKAQSTWVESFLKQNGYLEFESLTRLGIPDPINYIKKRFKSSRLLFLKTACVGRTIVDQ-LEASVEEAINSATWVDLQPMLPSILSEEDVGILLNEVLRSMNVQSSARLLS-TSVVSEKFIAGCIALFEDLMQQKAQKEVKNNPVFLITEDDVKQSSA---LLETSASSKKDKRDERRKKAAEGGGSVKSGGGGNAREIRIRKTKKKGR--------KEEDSDEETTHSSQGRNKLGDVQFLSVEEIVEVLEEKVCDSSEEMLQELAEQLQRPLSKMYQEVVTTAFLSTSSSGAGGSRKKNMKDLQEEINNLYNNIRLFEKGTKLFSDETQATVAKHVLKTVCTDVTNVLLSFVAAEHMTS-DSSAAMTSEIRLKILAKLSDEVRSPLMKLHNSLNGKAIEEFLSCLETSAEECGLFLKKGDKKRERQALSVHRQALCEQLRDAEDPALVLHLTSVLLFQNVTHCMLHAPGRCVPHIIGFLQSKIPEDQHKLLSQYQSLVVKQLVVQGHGAEKKTVPPEGAGGPADSDDTESLQRELHSLSRDIKDTVLAQRKPSVTE--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VI55-1", "uniprot_id": "UFL1_DROME", "id": "Q9VI55-1", "name": "E3 UFM1-protein ligase 1 homolog", "aln": "MGSDWDEIKRLAADFQKAQLTSTLQKLSERNCVEIVTLLLEKQMLEVVFTNDGKEYITPDHLEREIQDELYVNGGRANLVEVSKTLNVDLSRIELLAERISAENQSVHLVLGQLIDEDYISHIAQEINEKLVQRGEVSISELASQFDLPSDFLQHDVVEKHLGKIIKGRQDASNPRVFFTQAYIQRCKAKIRGALAAITRPINVAVILQKIGVQEKIFYSLLDEIAPAG-----QVTSKQANSQYVPHIYAKTQADWVNSFYKQNSFLEYDAIQKLGISDAKSYIRKQFPNEEFLYLKRVALGARLVELTVVTALNECSATKQYLDLTTILPSNLSEEDIEEVFSTIMAQKHSNPSNFVYLDGIVFSQPYLAQLVQPCQALAESQAKAAIDGGVYQQYIVEKTLAQKGNVSTQELEDEGKVDKRDERRKKASSG----KAGGGAQGRETKTKSTKKHQRGKAAAQFDSDDEDDAQQGSRGGGGASKKAVKPLELVKTADIVKLITASLEEEGLEHLSKSIASLYTNQFNQTALARAQELFEATPQTNRRQTHAAIQDRINTLLIDIRLYEKGLKLFPQDTQTQLVKYLLKSLGNEICNELSLYVASECNLTVKNTN-LNVDQRNKLAQECEAQYRAALLEQNKALN-KSIDDFELATETVLKTCSMIIKKVDKKKDRLLIADHKKKLQKQLLECNEPALLLHLAALILFTTITGSILHASGKFVSAILQHIRGSLNEDQNALLLRYHDLVLQVLQAIP-----------------DSNESKLANEHLQTMQNQVVELAQNFSRASISKAD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 217, "similar_positions": 311, "identity": "26.79%" }, { "cls_id": "homologset.agr.RGD:1309309", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZRI4-1", "uniprot_id": "D3ZRI4_RAT", "id": "D3ZRI4-1", "name": "", "aln": "--MSYPQFGYP-YSSAPQFLMTTN--------------------------------------------------------------------------------------------------------SLSTCCESGGRTLADSGPAASAQAPVYCPVYESRLLATARHELNSAAA---LGVYGSPYSSSQGYGNYVTYGSEASAFYS--LNSFESKDGTG----SSHAGLPPTAAAAYYPYEPTLGQYP------YDRYGTVDSGTRRKNATRETTSTLKAWLQEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWPPRNKCADEKRPYGEGEEEEAGEEESREEPLKSVKSEGPAGKEDKE-------LELSDLEDFDPLDTET----SECELKTPFQPLDSVPERIPPSSDGPGTGKEAPVTLRMPLGTADGAVMDGDLERARNCLRSTVVAPD------SGAEGGPQACEAKLTFAPAGAPPNLETKPRIWSLAHTAT-------AAAATALSQTEFPSCMLKRQGSTGASAVT--PASSPAVPAA-SGTLDRHQD------------SPVTSLRNWVDGVFHDPILRHSTLNQAWATA----------------------------------------------------KGALLDPGPLGRNLGAGTNVLTTPLACSFRPTVPQDVSPAGASRELLATPKASGKPFCT--------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QY61-1", "uniprot_id": "IRX4_MOUSE", "id": "Q9QY61-1", "name": "Iroquois-class homeodomain protein IRX-4", "aln": "--MSYPQFGYP-YSSAPQFLMTTN--------------------------------------------------------------------------------------------------------SLSTCCESGGRTLADSGPAASAQAPVYCPVYESRLLATARHELNSAAA---LGVYGSPYGSSQGYGNYVTYGSEASAFYS--LNSFESKDGTG----SSHAGLPPTAAAAYYPYEPALSQYP------YDRYGTVDSGTRRKNATRETTSTLKAWLQEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWPPRNKCADEKRPYGEGEEEEAGEEESREEPLKSAKSEGHAGKDDKE-------LELSDLEDFDPLDAET----SECELKTPFQSLDSGPERIPASSDGPGTGKEASTTLRMPLGTAGGAVMDGDLERARNCLRSTVVVPD------SGAEGGPPACEAKLTFAQAGAPPNLETKPRIWSLAHTAT-------AAAATALSQTEFPSCMLKRQGPTGVSATT--PASSPAVTAP-SGALDRHQD------------SPVTSLRNWVDGVFHDPILRHSTLNQAWATA----------------------------------------------------KGALLDPGPLGRNLGAGTNVLTTPLACSFPPTVPQDVPPAGASRELLATPKAGGKPFCT--------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P78413-1", "uniprot_id": "IRX4_HUMAN", "id": "P78413-1", "name": "Iroquois-class homeodomain protein IRX-4", "aln": "--MSYPQFGYP-YSSAPQFLMATN--------------------------------------------------------------------------------------------------------SLSTCCESGGRTLADSGPAASAQAPVYCPVYESRLLATARHELNSAAA---LGVYGGPYGGSQGYGNYVTYGSEASAFYS--LNSFDSKDGSG----SAHGGLAP-AAAAYYPYEPALGQYP------YDRYGTMDSGTRRKNATRETTSTLKAWLQEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWPPRNKCADEKRPYAEGEEEEGGEEEAREEPLKSSKNAEPVGKEEKE-------LELSDLDDFDPLEAEP----PACELKPPFHSLDGGLERVPAAPDGP--VKEASGALRMSLAAGGGAALDEDLERARSCLRSAAAGPEPL----PGAEGGPQVCEAKLGFVPAGASAGLEAKPRIWSLAHTATAA-----AAAATSLSQTEFPSCMLKRQGPAAPAAVSSAPATSPSVALPHSGALDRHQD------------SPVTSLRNWVDGVFHDPILRHSTLNQAWATA----------------------------------------------------KGALLDPGPLGRSLGAGANVLTAPLARAFPPAVPQDAPAAGAARELLALPKAGGKPFCA--------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PJE4-1", "uniprot_id": "A0A8M9PJE4_DANRE", "id": "A0A8M9PJE4-1", "name": "", "aln": "--MSYPQFGYP-YSSAPQFLMTTN--------------------------------------------------------------------------------------------------------SLTSCCESSTRSIPDS----SAQTPVYCPVYESRLLATARHELSSAAA---LGVYGSPYTGGQGYGNYVTYGADASAFYS--LGTFDAKDGSA----SAHAGITP--AAAYYPYDPTLGQYQ------YDRYGSMEGGTRRKNATRETTSTLKAWLQEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWPPRNKGSDEKK-YDD-DEDGSPEEQIKSETNDDAESKD---REDKD-------LQLSDLEDFDPLESES----PECELKHRFQ-----------------------ISAHMETKDPQKLSIPGLLEEAKSCLKS----PE-------DCELELRHSKACFQQQQQQSHPILDSKPRIWSLAQTAT------------SLNPAEFPSCMLR----------------CPASPSP-AGGPDRQQD------------SPVTTLRNWVDGVFHDPLFRHSSLNQTNTTVSWT------------------------------------------------NKGSILETGALGRSV--------------------ADSGKQEAGKDTMTFPKGVNKIFCS--------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24248-1", "uniprot_id": "ARA_DROME", "id": "Q24248-1", "name": "Homeobox protein araucan", "aln": "-MAAYTQFGYGGFPSASQLLPPSVQTTEDASANVNVNVNEALVMTNAPAMSPTGGQDCQGSQPSGGAGGDASSGALSPNALSQNSNAATVVGAGGGSSAGGGGPADLATGGSLDGNGVGTTPTAGGAGGGGSCCENGRPIMTDP---VSGQTVCSCQYDSARLALSSYSRLPAAS----VGVYGTPYPSTDQN-PYQSIGVDSSAFYSPLSNPYGLKDTGAGPEMGAWTSAGLQPTTGYYSYDP-MSAYGGLLVSNSSYGASYDLAARRKNATRESTATLKAWLNEHKKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWEPKNRTDDDDDALVSDDEKDKEDLEPSKGSQGSVS----LAKDETK-------EEEDAIDE--DQKCLG--QANILRAGFGYPSAGSGSGGYPGGGGSSS---GHPGGYHPYHHQHPAYYQAGQQGG---MLPFHGENS----------KLQTDLGDPKNQLGRDCGVPIPATKPKIWSLADTVGCKT---PPP--AYMGHQSMPLQQQQQQQQQQQQAQHQYPPSEAGRDQQLFNGAAAPYLRPHTTAYGGFLGATTQQLHTTNNSIPYSNMPPQQQQPQQQQQQLQQGGTIHTTGSSSGPIIPLQFHNRHPQQQQQLQQQSQSTASQRAMGFLEAQPDTPPQTPPNMKVLS--------GALSLLPTATQVPMTATCRSSNAFGFPASGYPMNFSARLGEYSPRDDYSSGNSSSSSSSSPQLQRNEAMFKPLFKKFTN-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P54269-1", "uniprot_id": "CAUP_DROME", "id": "P54269-1", "name": "Homeobox protein caupolican", "aln": "-MAAYAQFGYAGYPTANQLTTANTDSQSGHGG------GSPLSGTNEASLSPSGGSTATG----------LTAGPLSPGAVSQSSHHA---GHKGLSTS----PAEDVVGGDVP---VGLSSAAQDLPSRGSCCENGRPIITDP---VSGQTVCSCQYDPARLAIGGYSRMALPSGGVGVGVYGGPYPSNEQN-PYPSIGVDNSAFYAPLSNPYGIKDTSPSTEMSAWTSASLQSTTGYYSYDPTLAAYG--------YGPNYDLAARRKNATRESTATLKAWLSEHKKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWEPKNKTEDDDDGMMSDDEKEKDAGDGGKLSTEAFDPGNQLIKSELG-------KAEKEVDSSGDQKLDLDREPHNLVAMRGLAPYATPPGAHPMHAAYSSYAQSHNTHTHPHPQQMQHHQQQQQQQQNQQQLQHHQMDQPYYHPGGYGQEESGEFAAQKNPLSRDCGIPVPASKPKIWSVADTAACKT---PPPTAAYLGQNFYPPSSADQQLPHQPLQQHQQQQLQQLQQQQQHHHHPHHHHPHHSMELG----SPLSMMSSYAGGSPYSRIPTAYTEAMGMHLPSSS-----SSSSSTGKLPPTHIH---PAPQR--------------VGFPEIQPDTPPQTPPTMKLNSSGGSSSSSGSSHSSSMHSVTPVTVASMVNILYSNTDSGYGHGHSHGHGHG---HGHGLGHGHGLGHGHGHMGVTSNAYLTEGGRSGS-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "M9PI45-1", "uniprot_id": "M9PI45_DROME", "id": "M9PI45-1", "name": "", "aln": "MTVHSNETGICLVMNAVSTHLATSSPNTPPTNAPQSPPSTLPTLACPAAQPLSAPGIAGPG--------------HSGMVTSTVPPGARSTSPCGPSAGLPALSLVGAPPPGPHSSAPGGAPAPGAGNPPNRCCDTGRTIYTDP---VSGQTICSCQYDMLN-----YQRLAAAGG-VPLGVYPEGMSAYLSG-----IAADQPPFYA---NPAGIDLKEN----LVAGASPWPYPSMYHPYDAAFAGYP------FNSYGMDLNGARRKNATRETTSTLKAWLNEHKKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWEPRNRVDDDDANIDDDDDKNTEDNDLLDAKDSGVGSTDDKDRSGRLGDMMTDRPGESNNSEWSESRPGSPNGSPDLYDRPGSMPPGAHPLFHPAALHHHFRPPAGSPPDIAAYHHHQQQLLQQHQQAQQNSLQTAVGGTAKPR-IWSLADMASKDSKDSSSGAKDNHPELPPAHPGFYGHPGQQPSPGKILSPLAARIPNYSPYVRPDLYRGFYGPAAAHLGAPTQEFLEHQRTFGASLAAHNGPLGMN----PLLWKAAVSGAANGHHFAPLSLTTSGGSSGGQQVAP--------------------------------------------PPVASPSASSSSSSMGCDVVHIPTSSGQSAAQHMMGPISSNSTASSSSSHSGKISPGVNVTSLSAKPXHPSAASPDPELGAAPIASPISAFRSLIAFREQQKLTLLRP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * .* . .. **:.. .*. *.*: * . .: .. :*** . . : ..**: .. . . .: *:.*:. :. * .:********:*:******.**:******************************************* *:*: *:. . ::. : . :. . .. * . ::* ::. . . : .. . : .: .. . . . : ", "identical_positions": 81, "similar_positions": 78, "identity": "10.49%" }, { "cls_id": "homologset.agr.RGD:1309312", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q1M168-1", "uniprot_id": "ATCAY_RAT", "id": "Q1M168-1", "name": "Caytaxin", "aln": "----------------------------------------------------------------------------MGTTEATLRMENVDVRDEWQDEDLPRPLPEDTGEDHLGGTVEDSSSPPSTLNLS-----GAHRKRKTLVAPEINISLDQSEGSLLSDDFLDTPDDLDINVDDIETPDETDSLEFLGNGNE------------------------------------------------LEWEDDTP-------------------------VATAKNMPGDSADLFGDGSGEDGSAANGRLWRTVIIGE-QEHRIDLHMIRPYMKVVTHGGYYGEG-LNAIIVFAACFLPDSSSPDYHYIMENLFLYVISSLELLVAEDYMIVYLNGATPRRRMPGIGWLKKCYHMIDRRLRKNLKSLIIVHPSWFIRTVLAISRPFISVKFISKIQYVHSLEELEQLIPMEHVQLPACVLQYEEQRLRAKRESARPPQPEFLLPRSEEKPETVEEEDRAAEVTEDQETSMS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BHE3-1", "uniprot_id": "ATCAY_MOUSE", "id": "Q8BHE3-1", "name": "Caytaxin", "aln": "----------------------------------------------------------------------------MGTTEATLRMENVDVRDEWQDEDLPRPLPEDTGVERLGGAVEDSSSPPSTLNLS-----GAHRKRKTLVAPEINISLDQSEGSLLSDDFLDTPDDLDINVDDIETPDETDSLEFLGNGNE------------------------------------------------LEWEDDTP-------------------------VATAKNMPGDSADLFGDGSAEDGSAANGRLWRTVIIGE-QEHRIDLHMIRPYMKVVTHGGYYGEG-LNAIIVFAACFLPDSSSPDYHYIMENLFLYVISSLELLVAEDYMIVYLNGATPRRRMPGIGWLKKCYHMIDRRLRKNLKSLIIVHPSWFIRTVLAISRPFISVKFISKIQYVHSLEELERLIPMEHVQLPDCVLQYEEQRLRAKRESTRPPQPEFLLPRSEEKPETVEEEDRAAEATEDQETSMS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86WG3-1", "uniprot_id": "ATCAY_HUMAN", "id": "Q86WG3-1", "name": "Caytaxin", "aln": "----------------------------------------------------------------------------MGTTEATLRMENVDVKEEWQDEDLPRPLPEETGVELLGSPVEDTSSPPNTLNFN-----GAHRKRKTLVAPEINISLDQSEGSLLSDDFLDTPDDLDINVDDIETPDETDSLEFLGNGNE------------------------------------------------LEWEDDTP-------------------------VATAKNMPGDSADLFGDGTTEDGSAANGRLWRTVIIGE-QEHRIDLHMIRPYMKVVTHGGYYGEG-LNAIIVFAACFLPDSSLPDYHYIMENLFLYVISSLELLVAEDYMIVYLNGATPRRRMPGIGWLKKCYQMIDRRLRKNLKSLIIVHPSWFIRTVLAISRPFISVKFINKIQYVHSLEDLEQLIPMEHVQIPDCVLQYEEERLKARRESARP-QPEFVLPRSEEKPEVAPVENRSALVSEDQETSMS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32T7U5-1", "uniprot_id": "A0AB32T7U5_DANRE", "id": "A0AB32T7U5-1", "name": "", "aln": "----------------------------------------------------------------------------MGTTEATLRMENMEVKDEWQDDDFPRPLPEDGDLDGLTDNSHHGALTADHLDS-------VRQKRRTLIAPDINLSLDKSEGSVLSDDFLETPDDLDINVDDIETPDD-DSLGSANNGTE------------------------------------------------LEWEDDTP-------------------------VASAKGPGGDD----GDGT--------GRLWRSVIIGD-QEHRIDMQVIRPYLRVVTHGGYYGEG-LNAIIVFAACYLPDSGCADYNYIMENLFLYVISSLEALVAEDYMIIYLNGATPRRRMPGISWLKRCYQMIERRLRKNLKCLIIAHPTWFIRTVLAISRPFVNVKFMDKIRYVQSLQELAQIVPMEHVQIPECVLQFDEERIKVQRERTEQ------VSKTSERPPSVAAEACP------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9P4L2-1", "uniprot_id": "A0A8M9P4L2_DANRE", "id": "A0A8M9P4L2-1", "name": "", "aln": "----------------------------------------------------------------------------MGSVDFGPLLEIIEARDEWLDDDFPRPLPAEGDMDSSCALSEGRTSPPNSLLIGGAGGGGAHRKRRTLVAPDMNLSLDQSEGSLLSDDFLDTPDDLDINVDDIETPDETDSLEFITNGND------------------------------------------------LEWEDDTP-------------------------VASAKAPPADSD---ADGEGVDGTGANGRLWRTVIIGE-QEHRIDMQVIRPYLRVISHGGYYGEG-LNAIIVFTACYLPDSSCPDYHYLMENLFLYVVSSLEMLVAEDYLIIYMNGGTPRSKMPGISWLKKCYQMIDRRLRKNLKSLIITHPSWFIRTVIAISKPFISVKFMNKIRYVHSLEELEKFVPMDHIHIPECILQYEEERLNARKERMEQ------EQKEQQHQEQQQKPTNPERTTAIEEPGL-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VZJ4-1", "uniprot_id": "Q9VZJ4_DROME", "id": "Q9VZJ4-1", "name": "CRAL-TRIO domain-containing protein", "aln": "MSLHYAESESSPSESKMDISETPTDSTGVSPLADDVLPTAPEKNILKLEQAKQDHDKEELEFKTTSALDNRILRPELLPMEAMPQRHNIIERTLANSHPLMSPTNTDSDSEPFQLKKQEKQLPRSNFPDVVPTTETVQVKNNLNQCRNKPQDAKVSLLRANSPDILSSESDADVSQYLAAVESNFQSVSLMPNGNGKKSKRSTALPGGEDISSLDSISNHSFDDDEDIEHNLASLSPSSSLIDGLDGEDDDDDCEGPELLPDHDDDLELDLEFGLATTPTPNAPASATAASTLPQYTAAEERRDSRNWQKITLPDGRTREIDMRVIEPYKRVLSHGGYLKSGGQNAIVIFCACHLPDRSRADYSYVMDNLFLYVVKTLEQLVTDDYVLIYLHGGSNRRNVPPFPWLKRCYQLLDRRLRKSLKHMYLVHPTFWIKSLVWMARPFVSTKFWRKLVYVKSLEELGMHVVVEKAAIPEKVKQYDAKRH--------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : . : : .. : * : . : . . . : .: *.. . : . . * * *:*.: .* *:. . .: :*: **. *: *** ..:.: . .* *:.: : : : :.**:::*.** :*::**** .* ***::* **.*** . .** *:*:******:.:** **::**:::*::*.: * .:* : ***:**::::*****.** : :.**:::*:::: :::**:..** *: **:**::* : ::: :* : *:: :* ", "identical_positions": 85, "similar_positions": 117, "identity": "16.1%" }, { "cls_id": "homologset.agr.RGD:1309313", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0KYP0-1", "uniprot_id": "A0ABK0KYP0_RAT", "id": "A0ABK0KYP0-1", "name": "", "aln": "MARTSRRRGTTSLGLRHPAAGRPTRVAWRRRGPGPYHGSSGVLAAPCSGPPAGCRSCGSGWVAAAEGRAGSSSAALGGLAASSFLQMGVSLFSSFSPCLPMKSRDEDGRSGNGAEAPPAAMGLDWPPAWLLGLPTAVVYGSLAFFTTILHNVFLLYYVDTFVSVYKINKVSFWVGETVFLLWNSFNDPLFGWLSDRRFLSSQPRSGAGLSSRDVVLTRVRALGWHGPLLALSFLAFWVPWAPAGLQFLLCLCLYDGFLTLVDLHHHALLADLALSAHDRTHLNFYCSLFSAAGAMSVFASYAFWNKEDFSSFRAFCVVLAAGSGLGFLGATQLLKRRIEATRKDRGCPGLVMDGGVCEEEPLVGGEEAGSITLGQYLRQLAHHQNFLWFVGMDLVQVFHCHFNSNFFPLFLEHLLSDHISLSTGSFLLGISYVAPHLNNLYFLPLCRRWGVYAVVRGLLLLKLSLSLLMLLAGPDHPGLLCFFIASNRVFTEGTCKLLTLVVTDLVDEDLVLNHRKQAASALLFGMVALVTKPGQTFAPLLGTWLLCFYTGHDLFQQPPVTSVGSVQPWPEP--PAPAPVQAPTLRQGCFYLLVLVPIICALLQLFTWSQFTLHGRRLRMVKAQRQNLAQIHTLNIKMV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PDE8-1", "uniprot_id": "S68A1_MOUSE", "id": "Q6PDE8-1", "name": "Solute carrier family 68 member 1", "aln": "------------------------------------------------------------------------------------------------------------------------MGLDWPQAWLLGLPIAVVYGSLALFTSILHNVFLLYYVDTFVSVYKINKVSFWVGETVFLLWNSFNDPLFGWLSDRQLLSSQPRSGAGLSSRDVVLTRVRALGWHGPLLALSFLAFWVPWAPAGLQFLLCLCLYDGFLTLVDLHHHALLADLALSSHDRTHLNFYCSLFSAAGSLSVFASYAFWNKEDFSSFRAFCVVLAAGSGLGFLGTTQLLKRQIEATRRDRGCPGLDLDGGVCEEEPPVGGEEAGNITLGQYLRQLARHQNFLWFVGMDLVQVFHCHFNSNFFPLFLEHLLSDHISLSTGSFLLGISYVAPHLNNLYFLPLCRRWGVYAVVRGLFLLKLSLSLLMLLAGPDHPGLLCFFIASNRVFTEGTCKLLTLVVTDLVDEDLVLNHRKQAASALLFGMVALVTKPGQTFAPLLGTWLLCFYTGHDLFQQSPMTPVGSVRPWPELPAPAPAPAQAPTLRQGCFYLLVFVPITCALLQLFTWSQFTLHGRRLRTVKAQRQNLAQIHTLNIKMV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14CX5-1", "uniprot_id": "S68A1_HUMAN", "id": "Q14CX5-1", "name": "Solute carrier family 68 member 1", "aln": "------------------------------------------------------------------------------------------------------------------------MGLGQPQAWLLGLPTAVVYGSLALFTTILHNVFLLYYVDTFVSVYKINKMAFWVGETVFLLWNSLNDPLFGWLSDRQFLSSQPRSGAGLSSRAVVLARVQALGWHGPLLALSFLAFWVPWAPAGLQFLLCLCLYDGFLTLVDLHHHALLADLALSAHDRTHLNFYCSLFSAAGSLSVFASYAFWNKEDFSSFRAFCVTLAVSSGLGFLGATQLLRRRVEAARKDPGCSGLVVDSGLCGEELLVGSEEADSITLGRYLRQLARHRNFLWFVSMDLVQVFHCHFNSNFFPLFLEHLLSDHISLSTGSILLGLSYVAPHLNNLYFLSLCRRWGVYAVVRGLFLLKLGLSLLMLLAGPDHLSLLCLFIASNRVFTEGTCKLLTLVVTDLVDEDLVLNHRKQAASALLFGMVALVTKPGQTFAPLLGTWLLCFYTGHDLFQQSLITPVGSAHPWPEP--PAPAPAQAPTLRQGCFYLLVLVPITCALLQLFTWSQFTLHGRRLHMVKAQRQNLSQAQTLDVKMV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***. * ******* ********:**:**********************::*************:***********::************** ***:**:*******************************************************:*****************::**********************.**..*******:****:*::**:*:* **.** :*.*:* ** **.***..****:******:*:******.**********************************:***:*************.**************:****.************ .***:***************************************************************************. :*.***.:**** *****.**************:*** *******************: ********:* :**::***", "identical_positions": 450, "similar_positions": 52, "identity": "70.42%" }, { "cls_id": "homologset.agr.RGD:1309314", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A2AIG8-1", "uniprot_id": "1A1L1_MOUSE", "id": "A2AIG8-1", "name": "1-aminocyclopropane-1-carboxylate synthase-like protein 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFCLPQQESTAPTTCTGSASTQDMDSGYGDGLQGECLRKPDQTQPKLYGVGDPTATFSSDSSCLSSRGRVIKWFWDSAEEGYRTYHMDEYDEDKNPSGIINLGTSENKLCFDLLSWRLTQGDMLHVEPSLLQYPDWRGHLFLREEVAKFLSFYCKSPAPLKPENVVVLNGCASLFSALATVLCEAGEALLIPTPYYGAITQHIYLYGNVRLAYVYLDSKVTGLNTRPFQLTVEKLEMVLQGVSSEGVKVKGLILINPQNPLGDVYSPEELQDFLRFAMRHKLHVIMDEVYMLSVFEESLGYRSVLSLERLPDPQRTHVMWATSKDFGMSGLRFGVLYTENQHVATAVASLCRYHGLSGLVQHQMAQLLRDHDWISQVYLPENHARLKAAHTYVSEELRALGIPFVSRGAGFFIWVDLRKYLCKGTFEEEALLWRQFLDNKVLLSSGKTFECKEPGWFRVVFSDKENRLRLGMQRMRQVLEGQSQVVEDASPCHAQEPQSQPR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1LXH1-1", "uniprot_id": "F1LXH1_RAT", "id": "F1LXH1-1", "name": "", "aln": "MSENGKEVSSQAAKTESSTQTPSHWESIHSKPRDQLKKRSSRKKAFKILQEKMLKLQCVFMDHFLQRTSQQMQCLPPGDQQCTRASRKQEKKMGFLLSQIINHIWSNTVKKLKFKVPPLPCSDSRCGIKAGHQALSSWQTGQPRPRLGDFEDAFADRTLSKRGTGIYEFYHLSFQGYEAYQTDKYHQDKNPSGYINLSTSENKLCLDLITARLTQCDMNFLDEAQLQYSDWKGEPSLREELASFLTHYCKAPTPLDPENVVVLNGCSSVFSSLVMVLCDPGDALLIPTPCYSGFTFSSYLYSKVELIPVYLESQVTETNKYSFQLTVDKLKLTLTQAKKKGKKVKGLVLINPQNPLGDVYTQGSLQEYLVFAKKHKLHVIMDEIYMLSVFEPTVTFHSILSIENLPDPNMIHMIWGTSKDFGMSGIRFGVLYTHNKEVASAMKAFGYHHSVSGIIQYKLRQLLQDKEWINKVYLPKNHSRLREAYSYVTKMLEDLKIPFCNCGSGLFVWINLKAYLNPCTFDQEQILHQRFQDKKLLLSSGKSFMCIEPGWFRLVFAEKHPQLQVVSGRQGSVEDPELPPLRPRGRVRTPSLCPRQVARGQATPVSRKYSPKNTARENPRSKVGAAIRHCTPKRPGSQPGSLNRFLPLGLEILSAVTLQTLWFRKTRAGPADHSVLVASFGLIFCLPQKDSTVPTTCTGSASTQDMESGYGDDLQGECLRKPDQKQPKLYGVGDPTATFSSDSFCLSSRGRVIKWFWDSAEEGYRTYHMDEYDEDKNPSGIINLGTSENKLCFDLLSWRLTQNDMLHVEPSLLQYPDWRGHRFLRKEVARFLSFYCKSPAPLKPENVVVLNGCASLFSALATVLCEPGEVLLIPTPYYGAITQHIYLYGNIRLAYVYLDSKVTGLNTRPFQLTVEKLEMALQGVNSEGVKVKGLILINPQNPLGDIYSPEELQDFLGFAMRHKLHVIMDEVYMLSVFEESLGYRSVLSLERLPDPQRTHVMWATSKDFGMSGLRFGVLYTENQHVATAVASLCRYHGLSGLVQHQMAQLLQDHDWISQVYLPENHARLKAAHTYVSEELRALGIPFVSRGAGFFIWVDLRKYLREGTFEEEAMLWRRFLDNKVLLSSGKTFECKEPGWFRVVFSDKENRLRLGMQRMRQVLKGQSQMVEDASRCHTQELQ----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96QU6-1", "uniprot_id": "1A1L1_HUMAN", "id": "Q96QU6-1", "name": "1-aminocyclopropane-1-carboxylate synthase-like protein 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFTLPQKDFRAPTTCLGPTCMQDLGSSHGEDLEGECSRKLDQKLPELRGVGDP-AMISSDTSYLSSRGRMIKWFWDSAEEGYRTYHMDEYDEDKNPSGIINLGTSENKLCFDLLSWRLSQRDMQRVEPSLLQYADWRGHLFLREEVAKFLSFYCKSPVPLRPENVVVLNGGASLFSALATVLCEAGEAFLIPTPYYGAITQHVCLYGNIRLAYVYLDSEVTGLDTRPFQLTVEKLEMALREAHSEGVKVKGLILISPQNPLGDVYSPEELQEYLVFAKRHRLHVIVDEVYMLSVFEKSVGYRSVLSLERLPDPQRTHVMWATSKDFGMSGLRFGTLYTENQDVATAVASLCRYHGLSGLVQYQMAQLLRDRDWINQVYLPENHARLKAAHTYVSEELRALGIPFLSRGAGFFIWVDLRKYLPKGTFEEEMLLWRRFLDNKVLLSFGKAFECKEPGWFRFVFSDQVHRLCLGMQRVQQVLAGKSQVAEDPRPSQSQEPSDQRR", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* ***:: .**** *.:. **: *.:*:.*:*** ** **. *:* ***** * :***: ******:************************************************:* ** :********.***** ***:***:*********.**:********* *************.**.:*************: ****:*********:****:*************.*: . ************.*******:*******::* ** **:****:**********:*:***********************************.******.*******************:******:*:***.*****************************:**************** :****** :***:********* **:**********.****: :** *****::*** *:**:.**. .::** . ", "identical_positions": 399, "similar_positions": 67, "identity": "33.7%" }, { "cls_id": "homologset.agr.RGD:1309315", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GIV1-1", "uniprot_id": "A0A8I6GIV1_RAT", "id": "A0A8I6GIV1-1", "name": "", "aln": "MRLDMSQGKPNSPTQSSDPFQQSSGARTRKHCAHPAACCLIQNWAKVQGCVKVERPKAANAWLSSTLKGESLCSLRRRSSWVVKPHAPLIKFPNRRDKPKLSASDTLR--SAALP--SHSSVISQHSKGN--LSPNLLMHQ-GPPDTAELIKSLPQKYRRKPMSQEEMEFIQRGGPE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQX8-1", "uniprot_id": "KGD4_MOUSE", "id": "Q9CQX8-1", "name": "Alpha-ketoglutarate dehydrogenase component 4", "aln": "-------------------------------------------------------------------MGSKMASATR-VVQVVKPHAPLIKFPNRRDKPKLSASEALG--SAALP--SHSSAISQHSKGS--TSPDLLMHQ-GPPDTAEIIKSLPQKYRRKPMSQEEMEFIQRGGPE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P82909-1", "uniprot_id": "KGD4_HUMAN", "id": "P82909-1", "name": "Alpha-ketoglutarate dehydrogenase component 4", "aln": "------------------------------------------------------------------MMGSKMASASR-VVQVVKPHTPLIRFPDRRDNPKPNVSEALR--SAGLP--SHSSVISQHSKGS--KSPDLLMYQ-GPPDTAEIIKTLPQKYRRKLVSQEEMEFIQRGGPE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8WHV7-1", "uniprot_id": "A8WHV7_DANRE", "id": "A8WHV7-1", "name": "", "aln": "--------------------------------------------------------------MGSKVSG-KMAAASR-VVQVVRPHAPLIKFPDRKGVSRPNVQEALKVLTASLPQLSQSTAPSAASVSPPPRPPGPASRLPGTPDSIAVVRELPQRYRRRTLDLNEMDYIQRGGPE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .:.: * **:**:***:**:*:. .: ...::* :*.** *:*:. * * . .*. *.**: ::: ***:***: :. :**::*******", "identical_positions": 39, "similar_positions": 37, "identity": "22.03%" }, { "cls_id": "homologset.agr.RGD:1309316", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q80XS7-1", "uniprot_id": "FA83E_MOUSE", "id": "Q80XS7-1", "name": "Protein FAM83E", "aln": "MAASQLAALEGEELGAGEPALTKASPAVLYSEGQRLALEALLSSGEETFWACVQQERLPPFLSADEAQALATAAEDWLVPSQEPGAAGTGTAITDGDVGSLTYWPRQSEEPAPLLRLGWPEDTAWKGITRAQLYTQPPGEGQPPIKELVHQEIQAARKLVAVVMDVFTDPDLLRDMVDAATRRWIPVYLLLDHQHLPAFLALAQQLGVNLWTTENLDIRTVQGHTFQSRRRRQVSGHVREKFVLLDGDRVISGSYSFTWSDSRLHRSLVTLLTGEIADAFNQEFRVLYAASRPLSAAPARSPLFSPPEGPQLPRSPHRVALRCPVAPVAPLLSDGPLAQRLAACHILERDKQETPTTTGPALSDILRSVQRTRTTSGPPTRPSRSLWDLSRLSQLSGSSDGENESKKFWVSKDTPARALMRQRGTGGGPRAEMDSRSQPWGGPLPSIPARRLRYLSPAQRRLGDNAT----------TSDWASGSGSGRRR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZT45-1", "uniprot_id": "D3ZT45_RAT", "id": "D3ZT45-1", "name": "", "aln": "MAASQLAALEGEELGAVEPAPTKACPASLYSEGQRLALEALLSSGEEAFWACVQQERLPPFLSADEAQALATAAEDWIVPSQEPGATGTGAGIADGDFGSLTYWPRQSEEPAPSLRLGWPEDIAWKGITRAQLYTQPPGEGQPPVKELVRQEIQAARKLVAVVMDIFTDPDLLRDMVDAATRRWIPVYLLLDHQHLPAFLALAQQLGVNLWTTENLDIRTVQGHTFQSRRRRQVSGHVREKFLLLDGDRVISGSYSFTWSDSRLHRGLVTLLTGEIADAFSQEFRVLYAASRPLPPAPARSPLFSPPEGPQLPRSPHRVALRCPVAPVAPLLSDGPLAHRLAACHILEGDRRETPTTTGPALSDILRSVQRTRTTSGPPTRPSRSLWDLSRLSQLSGSSDGENEPKKSWGSKDTPARALMRQRGTGGGPRAEMDLRSQPWVGPLPIPAQRRLRYLSPAQRRLGDNAT----------TSDWASGSGSGRRR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q2M2I3-1", "uniprot_id": "FA83E_HUMAN", "id": "Q2M2I3-1", "name": "Protein FAM83E", "aln": "MAASQLAALEGVDSGPRVPG---ASPGFLYSEGQRLALEALLSKGAEAFQTCVQREELWPFLSADEVQGLAAAAEDWTVAKQEPSGMAEGATTTDVDAGSLSYWPGQSEQPAPVLRLGWPVDSAWKGITRAQLYTQPPGEGQPPLKELVRLEIQAAHKLVAVVMDVFTDPDLLLDLVDAATRRWVPVYLLLDRQQLPAFLELAQQLGVNPWNTENVDVRVVRGCSFQSRWRRQVSGTVREKFVLLDGERVISGSYSFTWSDARLHRGLVTLLTGEIVDAFSLEFRTLYAASCPLPPAPPQKP--SVIGGLQRGRSPHRVSRRRSVAPASPPPPDGPLAHRLAACRVS-------PATPGPALSDILRSVQRARTPSGPPARPSRSMWDLSRLSQLSGSSDGDNELKKSWGSKDTPAKALMRQRGTGGGPWGEVDSRP-PWGGALPLPPAHRLRYLSPARRRFGGDATFKLQEPRGVRPSDWAPRAGLGGQP", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*********** : *. *. *.*. ***************.* *:* :***:*.* *******.*.**:***** *..***.. . *: :* * ***:*** ***:*** ****** * *********************:****: *****:********:******* *:********:*******:*:***** ******** *.***:*:*.*:* :**** ****** *****:****:*************:****.*********.***. ***.***** **..**.:.* * * * ******: * .***.:* .*****:*****:: *:*.*************:**.****:*****:***************:** ** * ******:************ .*:* *. ** *.** . :********:**:*.:** .****. :* * : ", "identical_positions": 338, "similar_positions": 78, "identity": "68.84%" }, { "cls_id": "homologset.agr.RGD:1309317", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "P54854-1", "uniprot_id": "HXT15_YEAST", "id": "P54854-1", "name": "Hexose transporter HXT15", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASEQSSPEINADNLN---------SSAADVHVQPPGEKEWSDGFYDKE---------VINGNTPDAPKR------------------------------------------------------------------------------------------------------------------------------------------GFLGYLIIYLLCYPVSFGGFLPGWDSGITAGFINMDNFKMNFGSYKHSTGEYYLSNVRMGLLVAMFSVGCSIGGVAFARLADTLGRRLAIVIVVLVYMVGAIIQISSNHKWYQYFVGKIIYGLGAGGCSVLCPMLLSEIAPTDLRGGLVSLYQLNMTFGIFLGYCSVYGTRKYSNTAQWRIPVGLCFLWALIIIVGMLLVPESPRYLIECERHEEACVSIAKINKVSPEDPWVLKQADEINAGVLAQRELGEASWKELFSVKTKVLQRLITGILVQTFLQLTGENYFFFYGTTIFKSVG-LTDGFETSIVLGTVNFFSTIIAVMVVDKIGRRKCLLFGAASMMACMVIFASIGVKCLYPHG--QDGPSSKG-------------------AGNAMIVFTCFYIFCFATTWAPVAYIVVAESFPSKVKSKAMSISTAFNWLWQFLIGFFTPFITGSIHFYYGYVFVGCLVAM-FLYVFFFLPETIGLSLEEIQLLYEEGIKPWKSASWVPPSRRGASSRETEAKKKSWKEVLKFPKSFN", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P47185-1", "uniprot_id": "HXT16_YEAST", "id": "P47185-1", "name": "Hexose transporter HXT16", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASEQSSPEINADNLN---------SSAADVHVQPPGEKEWSDGFYDKE---------VINGNTPDAPKR------------------------------------------------------------------------------------------------------------------------------------------GFLGYLIIYLLCYPVSFGGFLPGWDSGITAGFINMDNFKMNFGSYKHSTGEYYLSNVRMGLLVAMFSVGCSIGGVAFARLADTLGRRLAIVIVVLVYMVGAIIQISSNHKWYQYFVGKIIYGLGAGGCSVLCPMLLSEIAPTDLRGGLVSLYQLNMTFGIFLGYCSVYGTRKYSNTAQWRIPVGLCFLWALIIIVGMLLVPESPRYLIECERHEEACVSIAKIDKVSPEDPWVLKQADEINAGVLAQRELGEASWKELFSVKTKVLQRLITGILVQTFLQLTGENYFFFYGTTIFKSVG-LTDGFETSIVLGTVNFFSTIIAVMVVDKIGRRKCLLFGAASMMACMVIFASIGVKCLYPHG--QDGPSSKG-------------------AGNAMIVFTCFYIFCFATTWAPVAYIVVAESFPSKVKSKAMSISTAFNWLWQFLIGFFTPFITGSIHFYYGYVFVGCLVAM-FLYVFFFLPETIGLSLEETQLLYEEGIKPWKSASWVPPSRRGASSRETEAKKKSWKEVLKFPKSFN", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P39924-1", "uniprot_id": "HXT13_YEAST", "id": "P39924-1", "name": "Hexose transporter HXT13", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSAQSSIDSDGDVR------------DADIHVAPPVEKEWSDGFDDNE---------VINGDNVEPPKR------------------------------------------------------------------------------------------------------------------------------------------GLIGYLVIYLLCYPISFGGFLPGWDSGITAGFINMDNFKMNFGSYKHSTGEYYLSNVRMGLLVAMFSIGCAIGGLIFARLADTLGRRLAIVIVVLVYMVGAIIQISSNHKWYQYFVGKIIYGLGAGGCSVLCPMLLSEIAPTDLRGGLVSLYQLNMTFGIFLGYCSVYGTRKYDNTAQWRVPLGLCFLWALIIIIGMLLVPESPRYLIECERHEEARASIAKINKVSPEDPWVLKQADEINAGVLAQRELGEASWKELFSVKTKVLQRLITGILVQTFLQLTGENYFFFYGTTIFKSVG-LTDGFETSIVLGTVNFFSTIIAVMVVDKIGRRKCLLFGAAGMMACMVIFASIGVKCLYPHG--QDGPSSKG-------------------AGNAMIVFTCFYIFCFATTWAPVAYIVVAESFPSKVKSRAMSISTACNWLWQFLIGFFTPFITGSIHFYYGYVFVGCLVAM-FLYVFFFLPETIGLSLEEIQLLYEEGIKPWKSASWVPPSRRGISSEESKTEKKDWKKFLKFSKNSD", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P53631-1", "uniprot_id": "HXT17_YEAST", "id": "P53631-1", "name": "Hexose transporter HXT17", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQSSTESDRDIQD---------GPDADIHVAPPVEKEWSDGFDDNE---------VINGDNVEPPKR------------------------------------------------------------------------------------------------------------------------------------------GLIGYLVIYLLCYPISFGGFLPGWDSGITAGFINMDNFKMNFGSYKHSTGEYYLSNVRMGLLVAMFSIGCAIGGLIFARLADTLGRRLAIVIVVLVYMVGAIIQISSNHKWYQYFVGKIIYGLGAGGCSVLCPMLLSEIAPTDLRGGLVSLYQLNMTFGIFLGYCSVYGTRKYDNTAQWRVPLGLCFLWTLIIIIGMLLVPESPRYLIECERHEEARASIAKINKVSPEDPWVLKQADEINAGVLAQRELGEASWKELFSVKTKVLQRLITGILVQTFLQLTGENYFFFYGTTIFKSVG-LTDGFETSIVLGTVNFFSTIIAVMVVDKIGRRKCLLFGAAGMMACMVIFASIGVKCLYPHG--QDGPSSKG-------------------AGNAMIVFTCFYIFCFATTWAPVAYIVVAESFPSKVKSRAMSISTACNWLWQFLIGFFTPFITGSIHFYYGYVFVGCLVAM-FLYVFFFLPETIGLSLEEIQLLYEEGIKPWKSASWVPPSRRGIPSEESKTEKKDWKKFLKFSKGSD", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P43581-1", "uniprot_id": "HXT10_YEAST", "id": "P43581-1", "name": "Hexose transporter HXT10", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVSSSVSILGTSAKA-------------STSLSR-------KDEIKLTP---------ETREASLDIPYK------------------------------------------------------------------------------------------------------------------------------------------PIIAYWTVMGLCLMIAFGGFIFGWDTGTISGFINQTDFKRRFG-ELQRDGSFQLSDVRTGLIVGIFNIGCALGGLTLGRLGDIYGRKIGLMCVILVYVVGIVIQIASSDKWYQYFIGRIVSGMGVGGVAVLSPTLISEISPKHLRGTCVSFYQLMITLGIFLGYCTNYGTKKYSNSIQWRVPLGLCFAWAIFMVIGMVMVPESPRYLVEKGKYEEARRSLAKSNKVTVTDPGVVFEFDTIVANMELERAVGNASWHELFSNKGAILPRVIMGIVIQSLQQLTGCNYFFYYGTTIFNAVG-MQDSFETSIVLGAVNFASTFVALYIVDKFGRRKCLLWGSASMAICFVIFATVGVTRLWPQG--KDQPSSQS-------------------AGNVMIVFTCFFIFSFAITWAPIAYVIVAETYPLRVKNRAMAIAVGANWMWGFLIGFFTPFITRSIGFSYGYVFMGCLIFS-YFYVFFFVCETKGLTLEEVNEMYEERIKPWKSGGWIPSSRRTPQPTSSTPLVIVDSK---------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P23585-1", "uniprot_id": "HXT2_YEAST", "id": "P23585-1", "name": "High-affinity glucose transporter HXT2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSEFATSRVESGSQQ-------------TSIHSTPIVQKLETDESPIQT---------KSEYTNAELPAK------------------------------------------------------------------------------------------------------------------------------------------PIAAYWTVICLCLMIAFGGFVFGWDTGTISGFVNQTDFKRRFG-QMKSDGTYYLSDVRTGLIVGIFNIGCAFGGLTLGRLGDMYGRRIGLMCVVLVYIVGIVIQIASSDKWYQYFIGRIISGMGVGGIAVLSPTLISETAPKHIRGTCVSFYQLMITLGIFLGYCTNYGTKDYSNSVQWRVPLGLNFAFAIFMIAGMLMVPESPRFLVEKGRYEDAKRSLAKSNKVTIEDPSIVAEMDTIMANVETERLAGNASWGELFSNKGAILPRVIMGIMIQSLQQLTGNNYFFYYGTTIFNAVG-MKDSFQTSIVLGIVNFASTFVALYTVDKFGRRKCLLGGSASMAICFVIFSTVGVTSLYPNG--KDQPSSKA-------------------AGNVMIVFTCLFIFFFAISWAPIAYVIVAESYPLRVKNRAMAIAVGANWIWGFLIGFFTPFITSAIGFSYGYVFMGCLVFS-FFYVFFFVCETKGLTLEEVNEMYVEGVKPWKSGSWISKEKRVSEE---------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P40885-1", "uniprot_id": "HXT9_YEAST", "id": "P40885-1", "name": "Hexose transporter HXT9", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSGVNNTSANDLSTT---------ESNSNSVANAPSVKTEHNDSKNSLN--------LDATEPPIDLPQK------------------------------------------------------------------------------------------------------------------------------------------PLSAYTTVAILCLMIAFGGFIFGWDTGTISGFVNLSDFIRRFG-QKNDKGTYYLSKVRMGLIVSIFNIGCAIGGIVLSKVGDIYGRRIGLITVTAIYVVGILIQITSINKWYQYFIGRIISGLGVGGIAVLSPMLISEVAPKQIRGTLVQLYQLMCTMGIFLGYCTNYGTKNYHNATQWRVGLGLCFAWTTFMVSGMMFVPESPRYLIEVGKDEEAKRSLSKSNKVSVDDPALLAEYDTIKAGIELEKLAGNASWSELLSTKTKVFQRVLMGVMIQSLQQLTGDNYFFYYGTTIFKSVG-LKDSFQTSIIIGVVNFFSSFIAVYTIERFGRRTCLLWGAASMLCCFAVFASVGVTKLWPQGSSHQDITSQG-------------------AGNCMIVFTMFFIFSFATTWAGGCYVIVSETFPLRVKSRGMAIATAANWMWGFLISFFTPFITGAINFYYGYVFLGCLVFA-YFYVFFFVPETKGLTLEEVNTMWLEGVPAWKSASWVPPERRTADYDADAIDHDDRPIYKRFFSS--", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P54862-1", "uniprot_id": "HXT11_YEAST", "id": "P54862-1", "name": "Hexose transporter HXT11", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSGVNNTSANELSTT---------MSNSNSAVGAPSVKTEHGDSKNSLN--------LDANEPPIDLPQK------------------------------------------------------------------------------------------------------------------------------------------PLSAYTTVAILCLMIAFGGFIFGWDTGTISGFVNLSDFIRRFG-QKNDKGTYYLSKVRMGLIVSIFNIGCAIGGIVLSKVGDIYGRRIGLITVTAIYVVGILIQITSINKWYQYFIGRIISGLGVGGIAVLSPMLISEVAPKHIRGTLVQLYQLMGTMGIFLGYCTNYGTKNYHNATQWRVGLGLCFAWATFMVSGMMFVPESPRYLIEVGKDEEAKRSLSKSNKVSVDDPALLVEYDTIKAGIELEKLAGNASWSELLSTKTKVFQRVLMGVMIQSLQQLTGDNYFFYYGTTIFKSVG-LKDSFQTSIIIGVVNFFSSFIAVYTIERFGRRTCLLWGAASMLCCFAVFASVGVTKLWPQGSSHQDITSQG-------------------AGNCMIVFTMFFIFSFATTWAGGCYVIVSETFPLRVKSRGMAIATAANWMWGFLISFFTPFITGAINFYYGYVFLGCLVFA-YFYVFFFVPETKGLTLEEVNTMWLEGVPAWKSASWVPPERRTADYDADAIDHDNRPIYKRFFSS--", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P39003-1", "uniprot_id": "HXT6_YEAST", "id": "P39003-1", "name": "High-affinity hexose transporter HXT6", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSQDAAIAEQTPVEH-----LSAVDSASHSVLSTPSNKAERDEIKAYGE--------GEEHEPVVEIPKR------------------------------------------------------------------------------------------------------------------------------------------PASAYVTVSIMCIMIAFGGFVFGWDTGTISGFINQTDFIRRFG-MKHKDGTNYLSKVRTGLIVSIFNIGCAIGGIILSKLGDMYGRKVGLIVVVVIYIIGIIIQIASINKWYQYFIGRIISGLGVGGIAVLSPMLISEVSPKHLRGTLVSCYQLMITAGIFLGYCTNFGTKNYSNSVQWRVPLGLCFAWALFMIGGMTFVPESPRYLAEVGKIEEAKRSIAVSNKVAVDDPSVLAEVEAVLAGVEAEKLAGNASWGELFSSKTKVLQRLIMGAMIQSLQQLTGDNYFFYYGTTIFKAVG-LSDSFETSIVLGIVNFASTFVGIYVVERYGRRTCLLWGAASMTACMVVYASVGVTRLWPNG--QDQPSSKG-------------------AGNCMIVFACFYIFCFATTWAPIPYVVVSETFPLRVKSKAMSIATAANWLWGFLIGFFTPFITGAINFYYGYVFMGCLVFM-FFYVLLVVPETKGLTLEEVNTMWEEGVLPWKSASWVPPSRRGANYDAEEMAHDDKPLYKRMFSTK-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P39004-1", "uniprot_id": "HXT7_YEAST", "id": "P39004-1", "name": "High-affinity hexose transporter HXT7", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSQDAAIAEQTPVEH-----LSAVDSASHSVLSTPSNKAERDEIKAYGE--------GEEHEPVVEIPKR------------------------------------------------------------------------------------------------------------------------------------------PASAYVTVSIMCIMIAFGGFVFGWDTGTISGFINQTDFIRRFG-MKHKDGTNYLSKVRTGLIVSIFNIGCAIGGIILSKLGDMYGRKVGLIVVVVIYIIGIIIQIASINKWYQYFIGRIISGLGVGGIAVLSPMLISEVSPKHLRGTLVSCYQLMITAGIFLGYCTNFGTKNYSNSVQWRVPLGLCFAWALFMIGGMTFVPESPRYLAEVGKIEEAKRSIAVSNKVAVDDPSVLAEVEAVLAGVEAEKLAGNASWGELFSSKTKVLQRLIMGAMIQSLQQLTGDNYFFYYGTTIFKAVG-LSDSFETSIVLGIVNFASTFVGIYVVERYGRRTCLLWGAASMTACMVVYASVGVTRLWPNG--QDQPSSKG-------------------AGNCMIVFACFYIFCFATTWAPIPYVVVSETFPLRVKSKAMSIATAANWLWGFLIGFFTPFITGAINFYYGYVFMGCLVFM-FFYVLLVVPETKGLTLEEVNTMWEEGVLPWKSASWVPPSRRGANYDAEEMTHDDKPLYKRMFSTK-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P32467-1", "uniprot_id": "HXT4_YEAST", "id": "P32467-1", "name": "Low-affinity glucose transporter HXT4", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSEEAAYQEDTAVQNTPADALSPVESDSNSALSTPSNKAERDDMKDFDEN-------HEESNNYVEIPKK------------------------------------------------------------------------------------------------------------------------------------------PASAYVTVSICCLMVAFGGFVFGWDTGTISGFVAQTDFIRRFG-MKHHDGTYYLSKVRTGLIVSIFNIGCAIGGIILAKLGDMYGRKMGLIVVVVIYIIGIIIQIASINKWYQYFIGRIISGLGVGGIAVLSPMLISEVSPKHIRGTLVSCYQLMITLGIFLGYCTNYGTKTYTNSVQWRVPLGLGFAWALFMIGGMTFVPESPRYLVEVGKIEEAKRSIALSNKVSADDPAVMAEVEVVQATVEAEKLAGNASWGEIFSTKTKVFQRLIMGAMIQSLQQLTGDNYFFYYGTTVFTAVG-LEDSFETSIVLGIVNFASTFVGIFLVERYGRRRCLLWGAASMTACMVVFASVGVTRLWPNG--KKNGSSKG-------------------AGNCMIVFTCFYLFCFATTWAPIPFVVNSETFPLRVKSKCMAIAQACNWIWGFLIGFFTPFISGAIDFYYGYVFMGCLVFS-YFYVFFFVPETKGLTLEEVNTLWEEGVLPWKSPSWVPPNKRGTDYNADDLMHDDQPFYKKMFGKK-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P32466-1", "uniprot_id": "HXT3_YEAST", "id": "P32466-1", "name": "Low-affinity glucose transporter HXT3", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNSTPDLIS-PQKSS------ENSNADLPSNSSQVMNMPEEK--GVQDDF--------QAEADQVLTNPN-----------------------------------------------------------------------------------------------------------------------------------------TGKGAYVTVSICCVMVAFGGFVFGWDTGTISGFVAQTDFLRRFG-MKHKDGSYYLSKVRTGLIVSIFNIGCAIGGIILAKLGDMYGRKMGLIVVVVIYIIGIIIQIASINKWYQYFIGRIISGLGVGGIAVLSPMLISEVAPKEMRGTLVSCYQLMITLGIFLGYCTNFGTKNYSNSVQWRVPLGLCFAWALFMIGGMTFVPESPRYLVEAGQIDEARASLSKVNKVAPDHPFIQQELEVIEASVEEARAAGSASWGELFTGKPAMFKRTMMGIMIQSLQQLTGDNYFFYYGTTVFNAVG-MSDSFETSIVFGVVNFFSTCCSLYTVDRFGRRNCLLYGAIGMVCCYVVYASVGVTRLWPNG--EGNGSSKG-------------------AGNCMIVFACFYIFCFATTWAPIAYVVISETFPLRVKSKAMSIATAANWLWGFLIGFFTPFITGAINFYYGYVFMGCMVFA-YFYVFFFVPETKGLTLEEVNDMYAEGVLPWKSASWVPTSQRGANYDADALMHDDQPFYKKMFGKK-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P32465-1", "uniprot_id": "HXT1_YEAST", "id": "P32465-1", "name": "Low-affinity glucose transporter HXT1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNSTPDLIS-PQKSN------SSNSYELESGRSKAMNTPEGKNESFHDNL-------SESQVQPAVAPPN-----------------------------------------------------------------------------------------------------------------------------------------TGKGVYVTVSICCVMVAFGGFIFGWDTGTISGFVAQTDFLRRFG-MKHHDGSHYLSKVRTGLIVSIFNIGCAIGGIVLAKLGDMYGRRIGLIVVVVIYTIGIIIQIASINKWYQYFIGRIISGLGVGGITVLSPMLISEVAPSEMRGTLVSCYQVMITLGIFLGYCTNFGTKNYSNSVQWRVPLGLCFAWALFMIGGMMFVPESPRYLVEAGRIDEARASLAKVNKCPPDHPYIQYELETIEASVEEMRAAGTASWGELFTGKPAMFQRTMMGIMIQSLQQLTGDNYFFYYGTIVFQAVG-LSDSFETSIVFGVVNFFSTCCSLYTVDRFGRRNCLMWGAVGMVCCYVVYASVGVTRLWPNG--QDQPSSKG-------------------AGNCMIVFACFYIFCFATTWAPIAYVVISECFPLRVKSKCMSIASAANWIWGFLISFFTPFITGAINFYYGYVFMGCMVFA-YFYVFFFVPETKGLSLEEVNDMYAEGVLPWKSASWVPVSKRGADYNADDLMHDDQPFYKSLFSRK-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P38695-1", "uniprot_id": "HXT5_YEAST", "id": "P38695-1", "name": "Probable glucose transporter HXT5", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSELENAHQGPLEGS------ATVSTNSNSYNEKSGNSTAPGTAGYNDNL-------AQAKPVSSYISHEGPPKDELEELQKEVDKQLEK---------------------------------------------------------------------------------------------------------------------KSKSDLLFVSVCCLMVAFGGFVFGWDTGTISGFVRQTDFIRRFG-STRANGTTYLSDVRTGLMVSIFNIGCAIGGIVLSKLGDMYGRKIGLMTVVVIYSIGIIIQIASIDKWYQYFIGRIISGLGVGGITVLAPMLISEVSPKQLRGTLVSCYQLMITFGIFLGYCTNFGTKNYSNSVQWRVPLGLCFAWSIFMIVGMTFVPESPRYLVEVGKIEEAKRSLARANKTTEDSPLVTLEMENYQSSIEAERLAGSASWGELVTGKPQMFRRTLMGMMIQSLQQLTGDNYFFYYGTTIFQAVG-LEDSFETAIVLGVVNFVSTFFSLYTVDRFGRRNCLLWGCVGMICCYVVYASVGVTRLWPNG--QDQPSSKG-------------------AGNCMIVFACFYIFCFATTWAPVAYVLISESYPLRVRGKAMSIASACNWIWGFLISFFTPFITSAINFYYGYVFMGCMVFA-YFYVFFFVPETKGLTLEEVNEMYEENVLPWKSTKWIPPSRRTTDYDLDATRNDPRPFYKRMFTKEK", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P40886-1", "uniprot_id": "HXT8_YEAST", "id": "P40886-1", "name": "Hexose transporter HXT8", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTDRKTNLPEEPIFE-------EAEDDGCPSIENSSHLSVPTVEENKD-----FSEYNGEEAEEVVVPEK------------------------------------------------------------------------------------------------------------------------------------------PASAYATVSIMCLCMAFGGFMSGWDTGTISGFVNQTDFLRRFGNYSHSKNTYYLSNVRTGLIVSIFNVGSAIGCLFLSKLGDIYGRCMGLIIVIVVYMVGIVIQIASIDKWYQYFIGRIIAGIGAGSISVLAPMLISETAPKHIRGTLLACWQLMVTFAIFLGYCTNYGTKTYSNSVQWRVPLGLCFAWAIIMIGGMTFVPESPRFLVQVGKIEQAKASFAKSNKLSVDDPAVVAEIDLLVAGVEAEEAMGTASWKELFSRKTKVFQRLTMTVMINSLQQLTGDNYFFYYGTTIFKSVG-MNDSFETSIVLGIVNFASCFFSLYSVDKLGRRRCLLLGAATMTACMVIYASVGVTRLYPNG--KSEPSSKG-------------------AGNCTIVFTCFYIFCFSCTWGPVCYVIISETFPLRVRSKCMSVATAANLLWGFLIGFFTPFITSAINFYYGYVFMGCLAFS-YFYVFFFVPETKGLTLEEVDEMWMDGVLPWKSESWVPASRRDGDYDNEKLQHDEKPFYKRMF----", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P13181-1", "uniprot_id": "GAL2_YEAST", "id": "P13181-1", "name": "Galactose transporter", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAVEENNMPVVSQQP-------QAGEDVISSLSKDSHLSAQSQKYSNDELKAGESGSEGSQSVPIEIPKK------------------------------------------------------------------------------------------------------------------------------------------PMSEYVTVSLLCLCVAFGGFMFGWDTGTISGFVVQTDFLRRFG-MKHKDGTHYLSNVRTGLIVAIFNIGCAFGGIILSKGGDMYGRKKGLSIVVSVYIVGIIIQIASINKWYQYFIGRIISGLGVGGIAVLCPMLISEIAPKHLRGTLVSCYQLMITAGIFLGYCTNYGTKSYSNSVQWRVPLGLCFAWSLFMIGALTLVPESPRYLCEVNKVEDAKRSIAKSNKVSPEDPAVQAELDLIMAGIEAEKLAGNASWGELFSTKTKVFQRLLMGVFVQMFQQLTGNNYFFYYGTVIFKSVG-LDDSFETSIVIGVVNFASTFFSLWTVENLGHRKCLLLGAATMMACMVIYASVGVTRLYPHG--KSQPSSKG-------------------AGNCMIVFTCFYIFCYATTWAPVAWVITAESFPLRVKSKCMALASASNWVWGFLIAFFTPFITSAINFYYGYVFMGCLVAM-FFYVFFFVPETKGLSLEEIQELWEEGVLPWKSEGWIPSSRRGNNYDLEDLQHDDKPWYKAMLE---", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q8MKK4-1", "uniprot_id": "TRE12_DROME", "id": "Q8MKK4-1", "name": "Trehalose transporter 1-like protein", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKILMRADTHVSFSVP-------------ADGLKAN-----------------------------------------------------------------------------------------------------------------------------------------------FTFSQVLAALSVSLCSLVVGFVSAYTS---PALVSMTDR-----TITSFEVTKDAGSWVGGIMPLAALAGGITGGPLIEYLGRRSTILATAVPFIVSSLLIACAVN-VIMILCGRFLTGFCVGIASLSLPVYLGETLQPEVRGTLGLLPTALGNIGILVCYVAG-------SFMNWSMLAFLGAALPVPFLILMIIIPETPRWFVNRGQEERARKALKWLRGKEADVEPELKELMQSQA--DADRQATQNTCLELF--KRNNLKPLSISLGLMFFQQFSGINAVIFYTVQIFKDAGSTIDSNLSTIIVGVVNFFATFMGIILIDRLGRKILLYVSDIAMIVTLSILGG-FFYCKAHGP----DVSHLG---------------------WLPLTCFVIYILGFSLGFGPIPWLMMGEILPAKIRGPAASVVTAFNWFCTFVVTKTFQDLTVAMGAHGAFWLFGAICIVGLFFVIIFVPETRGKSLEEIERKMMGRVP-MSSVVNIKPFPFNM-----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1Z8N1-1", "uniprot_id": "TRE11_DROME", "id": "A1Z8N1-1", "name": "Trehalose transporter 1", "aln": "MSGRDNRGAGGGGGGHQPLSNAMGKLKEKLTRVGDELGYHRVESNLSTSNTATSLDTILPEDPFLFPQVSPQRHPQNTVRTQRLLEDEPPLSFRPLLEDDDINEPPTQQQQRTPLRASGSLELTPLPPPPTSLEIREHRDRQQRGAQGDELQRSKQSLKGSRVSFERRDTGNSNTNSNKAAESSDEDSFEEKRTGFQQQKATSVDHKGILKDLKHILANDNRRQFQAKKHVSLDVKGT--------RFLQDLLKESSSEEEFHKTRREFQGRKHQSLDPRVTFKLDKVLQGSSTDSDEEGEDAEHKRLIHRPKDITKPVIIDLKDLESESDEDFLTSRQHFQQQRSISTDSRKSRRLYEMDEMDNKRGENIRHAVPFVRQITEDGKPKLEVYRPTTNPIYIWTQVLAALSVSLGSLVVGFVSAYTS---PALVSMTDR-----NITSFEVTQDAGSWVGGIMPLAGLAGGIAGGPLIEYLGRRNTILATAVPFIVSSLLIACAVN-VAMVLCGRFLAGFCVGIASLSLPVYLGETVQPEVRGTLGLLPTAFGNIGILLCFVAG-------SFMNWSMLAFLGAALPVPFLILMFLIPETPRWFVGRGLEERARKALKWLRGKEADVEPELKGLMRSQA--DADRQASRNTMLELL--KLNNLKPLSISLGLMFFQQFSGINAVIFYTVQIFKDAGSTIDGNLCTIIVGIVNFLATFIGIVLIDRAGRKILLYVSDIAMVLTLFVLGG-FFYCKTYGP----DVSHLG---------------------WLPLTCFVIYILGFSLGFGPIPWLMMGEILPAKIRGSAASVATAFNWFCTFVVTKTFQDLTVAMGAHGAFWLFGAICFVGLFFVIIYVPETQGKTLEDIERKMMGRVRRMSSVANIKPLSFNM-----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VU17-1", "uniprot_id": "Q9VU17_DROME", "id": "Q9VU17-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------MSTASSSNSSGEEANKKSGSNNEESSHLLESAENGAKYGSRQPVKIVKAS------------------DNGRTSSTPHDQENLLGN--------MVHTSTSNNS-----------------------------------------------------------------------------------------------------------------------------------------------QKWPQYVAALAAAGGAFAAGTVLGWTS---PAETEIVDRG----EGYDFPVDKDQFSWVGSAMTLGAACVCIPIGFLINMIGRKWTMLFLVLPFILGWTMLIWAVN-VSMLYASRFILGIAGGAFCVTAPMYTGEIAQKEIRGTLGSFFQLMITIGILFVYAVG-------AGVKIFWLSIICGILPLIFGAIFFFMPESPTYLVSKDRSENAIKSIQWLRGKEYDYEPELAELRETDR--ET-KANKVNVWAALN--RPVTRKALAISMGLMFFQQVCGINAVIFYASRIFLEANTGIEAEWATILIGIMQVVATFVSTLVVDKLGRRILLLASGISMAISTTAIGVYFFLQKQDAA----QVVSLG---------------------WLPVASLCLFIIMFSIGYGPVPWLMMGELFATDIKGFAGSLAGTSNWLLAFVVTKTFVNLNDGLGIGGTFWLFAGLTVVGVIFVYFAVPETKGKSLNEIQQELAGNRSTPQAIPAEK-----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0ABK0LPG5-1", "uniprot_id": "A0ABK0LPG5_RAT", "id": "A0ABK0LPG5-1", "name": "Solute carrier family 2, facilitated glucose transporter member 6", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQEPLLR---------------------AEGLDYDTFPEAP-ASPEE--------KARAGALQNR--------------------------------------------------------------------------------------------------------------------------------------------------RVFLATFAAVLGNFSFGYALVYTS---PVIPALKRS-----SDPALRLDKIQASWFGSVFTLGAAAGGLSAMLLNDLLGRKLSIMFSAVPSAIGYALMAGARG-LWMLLLGRMLTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALG-------LLLPWRWLAVAGEGPVLVMILLLSFMPNSPRFLLSKSRDEEALQALIWLR-ADSEVHWEFEQIQDN-----VRRQSSRVSWAEAW--EPRVYRPILITVLMRFLQQLTGITPILVYLQTIFDSTSVVLPSQQDAAIVGAVRLLSVLIAAVTMDLAGRKVLLYVSASIMFVANLTLGLYVQLVPRTLT----PNSTV--EIVTLGGTEQPPAAAFNYLTLIPLLATMLFIMGYAMGWGPITWLLMSEVLPLRARGVASGLCVLVSWLTAFVLTKYFLLAV------VPFFFFSAICLLSLLFTGCCVPETRGRSLEQIEAFFHTRRMSFRP----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UDF0-1", "uniprot_id": "GTR6_MOUSE", "id": "Q3UDF0-1", "name": "Solute carrier family 2, facilitated glucose transporter member 6", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQEPLLR---------------------TEGLDYDTFPEVP-ATPGE--------RERAGALKNR--------------------------------------------------------------------------------------------------------------------------------------------------RVFLATFAAVLGNFSFGYALVYTS---PVIPELKLS-----SDPALHLDKIQASWFGSVFTLGAAAGGLSAMLLNDLLGRKLSIMFSAVPSAIGYAIMAGARG-LWMLLLGRMLTGFAGGLTAACIPVYVSEIAPPDVRGALGATPQLMAVFGSLSLYALG-------LLLPWRWLAVAGEGPVLIMILLLSFMPNSPRFLLSKSRDEEALQALTWLR-ADSEVHWEFEQIQDN-----VRRQSSRVSWAEAR--EPRVYRPVLIAVLMRFLQQLTGITPILVYLQTIFDNTSVVLPSQQDAAIVGAVRLLSVLIAAVTMDLAGRKVLLYVSASVMFAANLTLGLYVQFVPRPLT----PNSTV--EIVTLGDT------AFNYLTLIPLLATMLFIMGYAMGWGPITWLLMSEVLPLRARGVASGLCVLVSWLTAFVLTNYFLLAVNAFGLQVPFFFFSAICLLSLLFTGCCVPETRGRSLEQIEAFFHTRRMSFRP----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UGQ3-1", "uniprot_id": "GTR6_HUMAN", "id": "Q9UGQ3-1", "name": "Solute carrier family 2, facilitated glucose transporter member 6", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQEPLLG---------------------AEGPDYDTFPEKPPPSPGD--------RARVGTLQNK--------------------------------------------------------------------------------------------------------------------------------------------------RVFLATFAAVLGNFSFGYALVYTS---PVIPALERS-----LDPDLHLTKSQASWFGSVFTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSAAGYALMAGAHG-LWMLLLGRTLTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALG-------LLLPWRWLAVAGEAPVLIMILLLSFMPNSPRFLLSRGRDEEALRALAWLRGTDVDVHWEFEQIQDN-----VRRQSSRVSWAEAR--APHVCRPITVALLMRLLQQLTGITPILVYLQSIFDSTAVLLPPKDDAAIVGAVRLLSVLIAALTMDLAGRKVLLFVSAAIMFAANLTLGLYIHFGPRPLS----PNSTAGLESESWGDLAQPLAAPAGYLTLVPLLATMLFIMGYAVGWGPITWLLMSEVLPLRARGVASGLCVLASWLTAFVLTKSFLPVVSTFGLQVPFFFFAAICLVSLVFTGCCVPETKGRSLEQIESFFRTGRRSFLR----------------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : : . . . . : :. : : ** : . : : .: : *: * * .* :** . : : : : ::*::* :: : * :: . : : *. * . .: * :* . : :.* :.. : . :: *:: * . * . : :::: :: :. ::: .* . :. .: . . *:: : :.. : .:. : ** * :*:: : ", "identical_positions": 26, "similar_positions": 94, "identity": "2.78%" }, { "cls_id": "homologset.agr.RGD:1309318", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LB28-1", "uniprot_id": "A0ABK0LB28_RAT", "id": "A0ABK0LB28-1", "name": "Adenylate cyclase type 1", "aln": "MAGAPRGQGGGGG-AGEPGGAERAAGPGGRRGFRACGEEFACPELEALFRGYTLRLEQAATLKALAVLSLLAGALALAELLGAPGPAPGLAKGSHPVHCILFLALFVVTNVRSLQVSQLQQVGQLALFFSLTFALLCCPFALGGPARSSAGGAMGSAVAEQGVWQLLLVTFVSYALLPVRSLLAIGFGLVVAASHLLVTAALVP--AKRPRLWRTLGANALLFFGVNMYGVFVRILTERSQRKAFLQARNCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLKPPERIFHKIYIQRHDNVSILFADIVGFTGLASQCTAQELVKLLNELFGKFDELATENHCRRIKILGDCYYCVSGLTQPKTDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVLCGVLGLRKWQYDVWSNDVTLANVMEAAGLPGKVHITKTTLACLNGDYEVEPGHGHERNTFLRTHNIETFFIVP-SHRRKIFPG---LILSDIKPAKRMKFKTVCYLLVQLMHCRKMFKAEIPFSNVMT--------------------------------CEDDD---------KRRALR---------------------------------------------------------TASEKLRNRSSFSTN---------------------VVYTTPGTRVNRYISRLLEARQTELEMAD-LNFFTLKYKHVEREQKYHQLQDEYFTSAVVLALILATLFGLIYLLVIPQSVAVLLLLVFSICFLVACTLYLHITRVQCFPG--CLTIQIRTALCVFIVVLIYSVAQGCVVSCLPWAWSSHSNSSLVVLAAGGRRTVLPALPCESAHHGLLCCLVGTLPLAIFLRVSSLPKMILLSGLTTSYILVLELSGYTKVGG-----GALSGRSYEPIMAILLFSCTLALHARQVDVRLRLDYLWAAQAEEERDDMERVKLDNKRILFNLLPAHVAQHFLMSNPRN-MDLYYQSYSQVGVMFASIPNFNDFYIELDGNNMGVECLRLLNEIIADFDELMDKDFYKDLEKIKTIGSTYMAAVGLAPTAGTRAK--KSISSHLSTLADFAIDMFDVLDEINYQSYNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVQGRIQVTEEVHRLLNRCSYQFVCRGKVSVKGKGEMLTYFLEG-----------------------------------------------------------------------------------------------------------------RTDGSSSHSRSLRLERRMFPYGRGGGGQARRP--------------------------------PLCPAAGPPIK---------------------------------------PGLSPAPTSQYLSSTAAGKEA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88444-1", "uniprot_id": "ADCY1_MOUSE", "id": "O88444-1", "name": "Adenylate cyclase type 1", "aln": "MAGAPRGQGGGGG-AGEPGGAERAAGPGGRRGFRACGEEFACPELEALFRGYTLRLEQAATLKALAVLSLLAGALALAELLGAPGPAPGLAKGSHPVHCILFLALFVVTNVRSLQVSQLQQVGQLALFFSLTFALLCCPFALGGPARSSAGGAMGSTVAEQGVWQLLLVTFVSYALLPVRSLLAIGFGLVVAASHLLVTAALVP--AKRPRLWRTLGANALLFFGVNMYGVFVRILTERSQRKAFLQARNCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLKPPERIFHKIYIQRHDNVSILFADIVGFTGLASQCTAQELVKLLNELFGKFDELATENHCRRIKILGDCYYCVSGLTQPKTDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVLCGVLGLRKWQYDVWSNDVTLANVMEAAGLPGKVHITKTTLACLNGDYEVEPGHGHERNTFLRTHNIETFFIVP-SHRRKIFPG---LILSDIKPAKRMKFKTVCYLLVQLMHCRKMFKAEIPFSNVMT--------------------------------CEDDD---------KRRALR---------------------------------------------------------TASEKLRNRSSFSTN---------------------VVYTTPGTRVNRYISRLLEARQTELEMAD-LNFFTLKYKHVEREQKYHQLQDEYFTSAVVLALILAALFGLIYLLVIPQSVAVLLLLVFSICFLVACTLYLHITRVQCFPG--CLTIQIRTALCVFIVVLIYSVAQGCVVGCLPWAWSSQSNSSLVVLAAGGRRTVLPALPCESAHHALLCCLVGTLPLAIFLRVSSLPKMILLSGLTTSYILVLELSGYTKVGG-----GALSGRSYEPIMAILLFSCTLALHARQVDVRLRLDYLWAAQAEEERDDMERVKLDNKRILFNLLPAHVAQHFLMSNPRN-MDLYYQSYSQVGVMFASIPNFNDFYIELDGNNMGVECLRLLNEIIADFDELMDKDFYKDLEKIKTIGSTYMAAVGLAPTAGTRAK--KSISSHLCTLADFAIDMFDVLDEINYQSYNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVQGRIQVTEEVHRLLKRCSYQFVCRGKVSVKGKGEMLTYFLEG-----------------------------------------------------------------------------------------------------------------RTDGNSSHGRTFRLERRMCPYGRGGG-QARRP--------------------------------PLCPAAGPPVR---------------------------------------PGLPPAPTSQYLSSTAAGKEA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q08828-1", "uniprot_id": "ADCY1_HUMAN", "id": "Q08828-1", "name": "Adenylate cyclase type 1", "aln": "MAGAPRGGGGGGGGAGEPGGAERAAGTSRRRGLRACDEEFACPELEALFRGYTLRLEQAATLKALAVLSLLAGALALAELLGAPGPAPGLAKGSHPVHCVLFLALLVVTNVRSLQVPQLQQVGQLALLFSLTFALLCCPFALGGPARGSAGAAGGPATAEQGVWQLLLVTFVSYALLPVRSLLAIGFGLVVAASHLLVTATLVP--AKRPRLWRTLGANALLFVGVNMYGVFVRILTERSQRKAFLQARSCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLKPPERIFHKIYIQRHDNVSILFADIVGFTGLASQCTAQELVKLLNELFGKFDELATENHCRRIKILGDCYYCVSGLTQPKTDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVLCGVLGLRKWQYDVWSNDVTLANVMEAAGLPGKVHITKTTLACLNGDYEVEPGYGHERNSFLKTHNIETFFIVP-SHRRKIFPG---LILSDIKPAKRMKFKTVCYLLVQLMHCRKMFKAEIPFSNVMT--------------------------------CEDDD---------KRRALR---------------------------------------------------------TASEKLRNRSSFSTN---------------------VVYTTPGTRVNRYISRLLEARQTELEMAD-LNFFTLKYKHVEREQKYHQLQDEYFTSAVVLTLILAALFGLVYLLIFPQSVVVLLLLVFCICFLVACVLYLHITRVQCFPG--CLTIQIRTVLCIFIVVLIYSVAQGCVVGCLPWAWSSKPNSSLVVLSSGGQRTALPTLPCESTHHALLCCLVGTLPLAIFFRVSSLPKMILLSGLTTSYILVLELSGYTRTGG-----GAVSGRSYEPIVAILLFSCALALHARQVDIRLRLDYLWAAQAEEEREDMEKVKLDNRRILFNLLPAHVAQHFLMSNPRN-MDLYYQSYSQVGVMFASIPNFNDFYIELDGNNMGVECLRLLNEIIADFDELMEKDFYKDIEKIKTIGSTYMAAVGLAPTSGTKAK--KSISSHLSTLADFAIEMFDVLDEINYQSYNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVQGRIQVTEEVHRLLRRCPYHFVCRGKVSVKGKGEMLTYFLEG-----------------------------------------------------------------------------------------------------------------RTDGNGSQIRSLGLDRKMCPFGRAGL-QGRRP--------------------------------PVCPMPGVSVR---------------------------------------AGLPPHSPGQYLPSAAAGKEA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P32870-1", "uniprot_id": "CYA1_DROME", "id": "P32870-1", "name": "Adenylate cyclase 1", "aln": "--------------------MDHAVKATRGRPLNTL--RFENDELECLYQRYTLKLQRFSVLGVVALVFVLCGVMAALSLTFNN--AATFHNIFNAIVCGLFAVVLVLLQCSVIKDHHLPTLCYGILLFTASICVVSMP-TLG-----SVFPVDTKEVMAEGVWQIVFVVFLAYAMMPLQIWEAVAFGIALPSVHISLTVYKIFTDALRYLEYNQLIANIVIFIGVNVAGLVVNIMMERAQRRTFLDTRNCIASRLEIQDENEKLERLLLSVLPQHVAMQMKNDILSPVAGQFHRIYIQKHENVSILFADIVGFTVLSSQCSAQELVRLLNELFGRFDQLAHDNHCLRIKILGDCYYCVSGLPEPRKDHAKCAVEMGLDMIDAIATVVEATDVILNMRVGIHTGRVLCGVLGLRKWQFDVWSNDVTLANHMESGGEPGRVHVTRATLDSLSGEYEVEAGHGDERSSYLRDHGVDTFFIVPPPHRRKPLMLNTLGVRSAIGSRRKLSFRNVSNVVMQLLHT-IKFSEPVPFSNIATGSFPSAASALGGGVSVGGGGGGGGGGVARGSTCEANSGNVQVSEKGSRKVIRLQKILHATPPPHGMGYGSVVGSGGGVDSGISGGGGCVSGGIAGGGGVQVTVGTNPNSTASTISRIHRHNHKNNKSQSKVADKFKRPFRKRHSVAAHHQPTNRVNRFLSQAINARSVDCDKSEHVDRLTLRFRQSDMEREYHKDFDLGFTTAMGCSLLLLILGAALQVTALPRTLILLLLFLFAFIWVSAILMLLLAVRLKWIIWDISESFSLRMAITIFTVILIYSVGQVNVFTCVSDHPCS-GNGTTSFQNDSHRKCSLPQYVSLSAAFAFLS-------VSVFLRLPIIFKSLLVLGMGTIYGLFIELSHQNIFECYDNRVNASIPLHLISLARIAIFMIAILVHGRLVEGTARLDFLWQLQASQEKKEMDVLQESNKRILHNLLPAHVAAHFLDAQFRNNMELYHQSYAKVGVIFASVPNFNEFYTEMDGSDQGLECLRLLNEIIADFDELLKEDRFRGIDKIKTVGSTYMAVVGLIPEYKIQPNDPNSVRRHMTALIEYVKAMRHSLQEINSHSYNNFMLRVGINIGPVVAGVIGARKPQYDIWGNTVNVASRMDSTGVPGYSQVTQEVVDSLVGSHFEFRCRGTIKVKGKGDMVTYFLCDSGNKSLNGEVRNAMSLPQSLHAPDYYMKVSQFPENRVNTDTYSKKENGHLYAGNGVEEQQLLLQHQHKQHDPLPLPAPPPPVHHHLHQQQQQRLNSKLQKQPIFMANGGLPNIRENGNGHNGEHQQQQQQQQQHQQQQQQQQQHGGFMVATTTPPAAVAVPLQPQHHQLQFQHPHQHPLPSAVSVPVQHQILLHHQLQLQHQPVPSVMLREFNIIENPTSGGRHQQMEQLPPHHGSLDLSGMGMGVGAGVLGSDCFMMPRRDRERTYVPPLNQHGHHPPHHLHSNLNLNQSQHPPSFTSLGYGQCRESEPLLHASSVAPVAKIMPMQHAPKYEPPRYTSPHTMLSQQHQQQQQQQHQHQQPQSQSAQDQQTHPAQDPHPLQRQYAMYSQQPQLPPKPVLRTYMKPLPKLPTDLEESRDMSSTDDLSSRPHSPSMSSSDESYSKTTEGEGEGDEDSPRMVNGGHLHHRNGYHLPAGGLVNPLQWLYPCDIQVDPTSPVVDMAHLHDFELSSTTESQGHHTNSNTTSNTQHKGDSCNSFDFQKAAVGTAAGAAIATKSPFERELQRLLNESSRARCLATATTTAGAISTTDQTASNGSRELSYSLSNGKLSSANGHGVGGSGSGSGSGSGSGSAVGNGSGGSGSSNGNLSGGSGSNSNSGNNNSSHHKTEQQQNMDHEHLAGGKLLGSNSFMIAKHPVGLEAIKEITRNKNPSESSQMQTSDTESCEILHENRNQMHVLAMLEMHTAKELNGSHAHHGQHHQQPQRTHRQRPRSKELQYSHESLDGLDGAVQSQSQQRHQRYHHHHHHQQRQQQQQRYNHVQEQEERDDTEDNLADEEFEDDEVGRDVRQKRLQKSELNHKRSEVATEAGNHHDDEVEEEDDDDDEEEDHRNGGREAAPLTNGSMRGLEANVINDELKYGATHLNHQSMDSNPLESQSEWSDDDCREEATGGAESTGYITDEPGLENISLLNEAGLTDAEGALSDVNSLYNAPDVDDTSVSSRASSRLLSLDSLSGLYDCDLDSKHELAIVNASHKISSKFGQPLSPAQQQHQQQQQQQQQQQQQHHQQQLQQNPQHTQAQSHLAPVQFQSAEELRE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::*. . * :.: .* ***.*:: ***:*:: :.* .:*:: :*.*.:* .* *. : : :.: * ** .::*: : :: :* : *:*: ::.::. * :** *. . . :****:::*.*::**::*:: *:.**:.:.: *: :*. : * * :. * ** ::*.***: *:.*.*: **:**::**::*.** .**.::***** ****:*:**::***:**:*:*.* **:****:*:************* *:***:*****:*******:**:** :*** ***************.:*:.***:*.*********:*::*.***:* ******:****************:*********** **:.* **:**:*::** .*.*:****.*:*.**.::*: *.::****** .**** : : * * . :::.*:.*. :::**:* *. :****: * ** :. .*:.:* *** * : .* ..: * .****::*: ::**..: : :: :: :**:::: : *::**: * **:*: :*:* * . : : :*::: :***::*.: :: * : * .*:: : . ::.:* .: :* *:*****.* *. *:. .* *.: . . :: ** . *: ..:*. :::*:*:. : * :*: *: * * *.:*** . .* .: * :* :: :*.* *: ***:** **.:*:.:*: :: .*:***.******** *** :: ** *:**:***::***:***:****:** *:**.: *:****************:.:* ::.::****:******.*** * :.: :*: *: :* ::. * . *:*** :***:*:******:***********:********************* * ***:** * . :.* ***.:.*****:*:**** . * :*.. : . ::: . : * :: *: . . .:: *.* . *.. . * * ", "identical_positions": 472, "similar_positions": 351, "identity": "20.64%" }, { "cls_id": "homologset.agr.RGD:1309320", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4A6J4-1", "uniprot_id": "D4A6J4_RAT", "id": "D4A6J4-1", "name": "DNA topoisomerase", "aln": "MIFPVTLLAFQWQRRPGGRALSRAAMEVAFRGVRKVLCVAEKNDAAKGIADLLSNGRMRRKEGLSKFNKIYEFDYHLY-----GQNVTMIMTSVSGHLLAHDFQMQFRKWQSCNPLVLFEAEIEKYCPENFIDIKKTLERETQHCQALVIWTDCDREGENIGFEIIHVCK---AVKPNLQVLRARFSEITHHAVRAACEHLTEPDQRVSDAVDVRQELDLRIGAAFTRFQTLRLQRIFP---------------EVLAEQLISYGSCQFPTLGFVVERFKAIQAFVPEVFHRIKVTHDHKD--GTVEFNWKRYRLFNHTACLVLYQLCMEDP--MATVVEVRSKPKSKWRPQALDTVELEKLASRKLRINAKETMRIAEKLYTQGYISYPRTETNIFPKDLNLVTLVEQQT--------QDPHWGAFAQNILERGGPTPRN-------GNKSDQAHPPIHPTKYT---SSLQGDDRRLYEFIVRHFLACCSQDAQGQETTVEIDIAQERFVAHGLIILARNYLDVYPYDHWS-DKLLPVYEQGFRFQPSTVEMVDGETSPPQLLTEADLIALMEKHGIGTDATHAEHIETIKARMYVG---LTSDKRFLPGHLGMGLVEGYDSMGYE--MSKPNLRAELEADLKLICEGKKDKFQVLRQQVQKYKQVFIEAVAKAKKLDEALSQYLGER--TEVAQQEEIYPAMP-----EPVRKCPQCNKD-MVLKTKKSG-GFYLSCTGFPECRSAVWFPDSVLEASRDSSVCSVCQP---APVYRLKLKFKRGSLPP-------------------SMPLEFVGCIG---------------------------------------------------------------------------------------------------------------------------------GCDETLKEIFG---------LRFSRAPPRASQP-------------------------------------SGHLQASQALNRMDSSQRSL---------------------SQPLVNRHTGPSKAVAQTLLPPTAAAEGNSVTCN-CGREAVLLTVRKQGPNQGRHFYKCSGGD-CNFFLWAD-------SSHPTGGGPPTSVSRPPGNSVGCPSGFGSHMD-GFGSLGGDG-----------------------DGGASCLCGQPAVTRTVQKDGPNKGRQFHTCAKPREQQCGFFQWVDENMAPGSFAAPAWPGGRGKAQRPEAASKRQRAGSLDAGSTVKKPRKCSLCHQPGHTRPFCPQNR----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70157-1", "uniprot_id": "TOP3A_MOUSE", "id": "O70157-1", "name": "DNA topoisomerase 3-alpha", "aln": "MIFPVTLLAFQWHRRPGGRALSRAAMEVAFRGVRKVLCVAEKNDAAKGIADLLSNGRMRRKEGLSKFNKIYEFDYHLY-----GQNVTMIMTSVSGHLLAHDFQMQFRKWQSCNPLVLFEAEIEKYCPENFIDIKKTLERETHHCQALVIWTDCDREGENIGFEIIHVCK---AVKPNLRVLRARFSEITPHAVRTACENLTEPDQRVSDAVDVRQELDLRIGAAFTRFQTLRLQRIFP---------------EVLAEQLISYGSCQFPTLGFVVERFKAIQAFVPEVFHKIKVTHDHKD--GTVEFNWKRYRLFNHTACLVLYQLCMEDP--MATVVEVRSKPKSKWRPQALDTVELEKLASRKLRINAKETMRIAEKLYTQGYISYPRTETNIFPKDLNLVALVEQQT--------VDPHWGAFAQTILERGGPTPRN-------GSKSDQAHPPIHPTKYT---SGLQGDDRRLYEFIVRHFLACCSQDAQGQETTVEIDIAQERFVAHGLIILARNYLDVYPYDHWS-DKLLPVYEQGSHFQPSTVEMVDGETSPPQLLTEADLIALMEKHGIGTDATHAEHIETIKARMYVG---LTSDKRFLPGHLGMGLVEGYDSMGYE--MSKPDLRAELEADLKLICEGKKDKFQVLRQQVQKYKQVFIEAVAKAKKLDEALSQYLGER--TEMAQQEEIYPAMP-----EPVRKCPQCNKD-MVLKTKKSG-GFYLSCMGFPECRSAVWFPDSVLEASRDNSVCSVCQP---PPVYRLKLKFKRGSLPP-------------------AMPLEFVGCIG---------------------------------------------------------------------------------------------------------------------------------GCDETLKEIFG---------LRFPRALPRASQP-------------------------------------SGHLQASQALNRMDSSQHNL---------------------SQPLVNRHTRPSKTVAQALLPPTTAGESNSVTCN-CGREAVLLTVRKQGPNQGRHFYKCSNGD-CNFFLWAD-------SSHSTGGGTPTSASGPPGSSVGCPSSVGSHMD-GFGSLGSDS-----------------------DGGTPCLCGQPAVTRTVQKDGPNKGRQFHTCAKPREQQCGFFQWVDENVAPGSFAAPAWPGGRGKAQRPEAASKRPRAGSSDAGSTVKKPRKCSLCHQPGHTRTFCPQNR----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13472-1", "uniprot_id": "TOP3A_HUMAN", "id": "Q13472-1", "name": "DNA topoisomerase 3-alpha", "aln": "MIFPVARYALRWLRRPEDRAFSRAAMEMALRGVRKVLCVAEKNDAAKGIADLLSNGRMRRREGLSKFNKIYEFDYHLY-----GQNVTMVMTSVSGHLLAHDFQMQFRKWQSCNPLVLFEAEIEKYCPENFVDIKKTLERETRQCQALVIWTDCDREGENIGFEIIHVCK---AVKPNLQVLRARFSEITPHAVRTACENLTEPDQRVSDAVDVRQELDLRIGAAFTRFQTLRLQRIFP---------------EVLAEQLISYGSCQFPTLGFVVERFKAIQAFVPEIFHRIKVTHDHKD--GIVEFNWKRHRLFNHTACLVLYQLCVEDP--MATVVEVRSKPKSKWRPQALDTVELEKLASRKLRINAKETMRIAEKLYTQGYISYPRTETNIFPRDLNLTVLVEQQT--------PDPRWGAFAQSILERGGPTPRN-------GNKSDQAHPPIHPTKYT---NNLQGDEQRLYEFIVRHFLACCSQDAQGQETTVEIDIAQERFVAHGLMILARNYLDVYPYDHWS-DKILPVYEQGSHFQPSTVEMVDGETSPPKLLTEADLIALMEKHGIGTDATHAEHIETIKARMYVG---LTPDKRFLPGHLGMGLVEGYDSMGYE--MSKPDLRAELEADLKLICDGKKDKFVVLRQQVQKYKQVFIEAVAKAKKLDEALAQYFGNG--TELAQQEDIYPAMP-----EPIRKCPQCNKD-MVLKTKKNG-GFYLSCMGFPECRSAVWLPDSVLEASRDSSVCPVCQP---HPVYRLKLKFKRGSLPP-------------------TMPLEFVCCIG---------------------------------------------------------------------------------------------------------------------------------GCDDTLREILD---------LRFSGGPPRASQP-------------------------------------SGRLQANQSLNRMDNSQH-----------------------PQPADSRQTGSSKALAQTLPPPTAAGESNSVTCN-CGQEAVLLTVRKEGPNRGRQFFKCNGGS-CNFFLWAD-------SPNPGAGGPPALAYRPLGASLGCPPGPGIHLG-GFGNPGDGS-----------------------GSGTSCLCSQPSVTRTVQKDGPNKGRQFHTCAKPREQQCGFFQWVDENTAPGTSGAPSWTGDRGRTLESEARSKRPRASSSDMGSTAKKPRKCSLCHQPGHTRPFCPQNR----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9NG98-1", "uniprot_id": "TOP3A_DROME", "id": "Q9NG98-1", "name": "DNA topoisomerase 3-alpha", "aln": "--MKAVLTCFRPVVASHRRYCANPGQAMKY------LNVAEKNDAAKTIAGLLSNGAAQRREGYSVYNKVFDFEAPVR-----GQNAKMVMTSVSGHMMQLAFQVSYKNWRTVDPRSLFDAPVKKGVGSDYEPIKRTLEREVRGCQGLIIWTDCDREGENIGYEIIDVCR---AIKPNISVYRATFSEITTVAVRRALQQLGQPDKRQSDAVDVRTELDLRTGAAITRFQTMRLQRLFP---------------EKIADKLISYGSCQIPTLGFVAERYKEIEAFVSEPFWKIKVLHTIDD--LTVEFNWARNRLFDKEACENYLLLCLAEPDPRALVESVTVKPKHKWRPTPLDTVEMEKLGSRKLKLSAKETMTIAEKLYTKGFISYPRTETNQFSKEFALAPLVEMQT--------GHRDWGAFAQRVIEWG-PNPRN-------GNKSDQAHPPIHPTKLA---ENLQGNEARVYELVVRHFLACVSKDAVGSETLVHIDIAGEKFTANGLVIHERNYLDVYVYDKWS-AKQIHHYENGQRFEPTEVSLHEGATTAPPLLTEADLIALMEKHGIGTDATHAEHINTIKERGYIG---VLDKGFLVPGVIGMGLYEGYDAMELA--LAKPQLRAEFELDLKLICQGQKDPKVVLTEQIAKYKQAYQQITDKITAMDAKISARINETPAANSAVQEGADGSAPSHGIIQSIFQCPKCNEAPLALKPKKNQQGWYIGCNNFPDCKNAVWLPTECKDASVLDECCPTCGDGYRMLKFRLSTPYYRGVFGTPSGWYKTCLPCDNLFRTTFNINLDSVKKVGGIVGEVRGGGGGPGPGPGGGGSGRGAGSGGWSSGPGGGGSGGGGGSGGWGSGTGGGGSGGWGSGTGGGGLGGGKGKKPGGESKKSATKKPPNEPKPKKTKEPKAAPNKKTSSKSSGSIRSFFTSAAPTNSASNGLDEFFDSNDGFEDAMLAAAESVESSSQPKTISMVPLDDDIAAAFAADDDAEFEALVNGGTMPTESNGDQQLDKSLSEWIKEQDKADERPMLWGTRERASLGTAAPTPPPKPAAKRPRWDSVERDSTPPSSVPESETVLCTGCQQPARQNTVRKNGPNLGRLYYKCPKPDECNFFQWADEPPSSAKSKNSTGSAPQSTTSWGSNRVVTLPSIQQSNSQRGQSSMRSNSSSTVTITQTKTKQQERNTATPGDGEEVMCNCGQLASQLTVRKDGPNQGRPFYACP-TREKSCGFFKWGDEDQNQGASST-----SWGSANRNPPGRSQPTAITSDG----PKTRRCGLCRKEGHTRNKCPRKDEFDM", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P13099-1", "uniprot_id": "TOP3_YEAST", "id": "P13099-1", "name": "DNA topoisomerase 3", "aln": "---------------------------------MKVLCVAEKNSIAKAVSQILGGGRSTSRDSGYMYVKNYDFMFSGFPFARNGANCEVTMTSVAGHLTGIDFSHDSHGWGKCAIQELFDAPLNEIMNNNQKKIASNIKREARNADYLMIWTDCDREGEYIGWEIWQEAKRGNRLIQNDQVYRAVFSHLERQHILNAARNPSRLDMKSVHAVGTRIEIDLRAGVTFTRLLTETLRNKLRNQATMTKDGAKHRGGNKNDSQVVSYGTCQFPTLGFVVDRFERIRNFVPEEFWYIQLVVENKDNGGTTTFQWDRGHLFDRLSVLTFYETCIETAGNVAQVVDLKSKPTTKYRPLPLTTVELQKNCARYLRLNAKQSLDAAEKLYQKGFISYPRTETDTFPHAMDLKSLVEKQAQLDQLAAGGRTAWASYAASLLQPENTSNNNKFKFPRSGSHDDKAHPPIHPIVSLGPEANVSPVERRVYEYVARHFLACCSEDAKGQSMTLVLDWAVERFSASGLVVLERNFLDVYPWARWETTKQLPRLEMNALVDIAKAEMKAGTTAPPKPMTESELILLMDTNGIGTDATIAEHIDKIQVRNYVRSEKVGKETYLQPTTLGVSLVHGFEAIGLEDSFAKPFQRREMEQDLKKICEGHASKTDVVKDIVEKYRKYWHKTN-----------------------------------------------------------------------ACKNTLLQVYDRVKASM------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *****. ** :: :*..* ::. : * ::* * * : ****:**: *. . : * . **:* ::: .: * .::**.: .: *:********** **:** . .: : * * ** **.: : * .: . * : .**..* *:*** *.::**: * *:. : : .:::***:**:******.:*:: *. **.* * *:: .* . *:* * :**:: : *: . * * .: **. *:** .* ***::* :* *::.**::: ***** :*:********: *.: : * *** *: *.::* ::: .. .* *.:.*:******* .:. : *:** :.****** *:** *.. : :* * *:* * **:: **:**** : :*. * : * . .: : ..: * *:.* :**::** **:.:******* ****:.*: * *: : . : * :*:.* .*:::: ::** * *:* *** **:*: . *: : : **:: : : *:.:: . .** ", "identical_positions": 209, "similar_positions": 183, "identity": "15.86%" }, { "cls_id": "homologset.agr.RGD:1309321", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JKP8-1", "uniprot_id": "CHRC1_MOUSE", "id": "Q9JKP8-1", "name": "Chromatin accessibility complex protein 1", "aln": "---------------------------------------------------------------------------MADAAVGK-EKCGDQRLVSLPLSRIRVIMKSSPEVSSINQEALVLTAKATELFVQYLATCSYRHGSG-KAKKA--------LTYSDLASTAEDSET--LQFLADILPKKILASKYLKMLKE-----------------------KREE-EEDNEDDGSDLGEALA-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LIV5-1", "uniprot_id": "A0ABK0LIV5_RAT", "id": "A0ABK0LIV5-1", "name": "Chromatin accessibility complex protein 1", "aln": "MPASSSKAAFERAGLCSSGLPEVLRRLKALLPGDCRSVSEGFFLGAVSQAFRPPRYTESAQARPRGASRAARTRKMADSVVGK-DKCGEQRLVSLPLSRIRVIMKSSPEVSSINQEALVLTAKATELFVQYLATCSYRHGSG-KAKKA--------LTYSDLASAAEDSET--LQFLADILPKKILASKYLKMLKE-----------------------KREE-EDD-DDDGSDLGEVPA-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NRG0-1", "uniprot_id": "CHRC1_HUMAN", "id": "Q9NRG0-1", "name": "Chromatin accessibility complex protein 1", "aln": "---------------------------------------------------------------------------MADVVVGK-DKGGEQRLISLPLSRIRVIMKSSPEVSSINQEALVLTAKATELFVQCLATYSYRHGSG-KEKKV--------LTYSDLANTAQQSET--FQFLADILPKKILASKYLKMLKEE----------------------KREEDEENDNDNESDHDEADS-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V452-1", "uniprot_id": "CHRC_DROME", "id": "Q9V452-1", "name": "Chromatin accessibility complex 16kD protein", "aln": "---------------------------------------------------------------------------MGEPRSQPPVERPPTAETFLPLSRVRTIMKSSMDTGLITNEVLFLMTKCTELFVRHLAGAAYTEEFGQRPGEA--------LKYEHLSQVVNKNKN--LEFLLQIVPQKIRVHQFQEMLRLN----------------------RSAGSDDDDDDDDDDDEEESESESESDE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40366-1", "uniprot_id": "DLS1_YEAST", "id": "P40366-1", "name": "Protein DLS1", "aln": "---------------------------------------------------------------------------MNNETSGKETASAPLCSPKLPVEKVQRIAKNDPEYMDTSDDAFVATAFATEFFVQVLTHESLHRQQQQQQQQVPPLPDELTLSYDDISAAIVHSSDGHLQFLNDVIPTTKNLRLLVEENRVRYTTSVMPPNEVYSAYVVNDTAPKPNIVEIDLDNDEDDDEDVTDQE-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : **:.::: * *.. : .::.:. : .**:**: *: : . : :. *.*..:: . ... ::** :::* . : : : : : ::: .* : ", "identical_positions": 16, "similar_positions": 50, "identity": "6.48%" }, { "cls_id": "homologset.agr.RGD:1309322", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZZR4-1", "uniprot_id": "D3ZZR4_RAT", "id": "D3ZZR4-1", "name": "Protein fem-1 homolog C", "aln": "MDLKTAVFNAARDGKLRLLTKLLASKSKAEVSSLISEKTNGATPLLMAARYGHLDMVEFLLEQCSASIEVGGSVNFDGETIEGAPPLWAASAAGHLKVVQSLLNHGASVNNTTLTNSTPLRAACFDGHLEIVKYLVEHKADLEVSNRHGHTCLMISCYKGHKEIAQYLLEKGADVNRKSVKGNTALHDCAESGSLDIMKMLLMYCAKMEKDGYGMTPLLSASVTGHTNIVDFLTHHAQTSKTERINALELLGATFVDKKRDLLGALKYWKKAMNMRYSDRTNIISKPVPQTLIMAYDYAKEVNSAEELEGLIADPDEMRMQALLIRERILGPSHPDTSYYIRYRGAVYADSGNFKRCINLWKYALDMQQSNLDPLSPMTASSLLSFAELFSFMLQDR----AKGLLGTTVTFDDLMGILCKSVLEIER-------------------------------------------AIKQTQCPADP--LQLNKALSIILHLICLLEKVP----CTLEQDHFKKQTIYRFLKLHPRGKNNFSPLHLAVDKNTTCVGRYPVCKFPSLQVTAILIECGADVNVRDSDDNSPLHIAALNNHPD-IMNLLIKSGAHFDATNLHKQTASDLLDEKEIAKNLIQPINHTTLQCLAARVIVNHRIYYKGNIPEKLETFVSLHR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CEF1-1", "uniprot_id": "FEM1C_MOUSE", "id": "Q8CEF1-1", "name": "Protein fem-1 homolog C", "aln": "MDLKTAVFNAARDGKLRLLTKLLASKSKAEVSSLISEKTNGATPLLMAARYGHLDMVEFLLEQCSASIEVGGSVNFDGETIEGAPPLWAASAAGHLKVVQSLLNHGASVNNTTLTNSTPLRAACFDGHLEIVKYLVEHKADLEVSNRHGHTCLMISCYKGHKEIAQYLLEKGADVNRKSVKGNTALHDCAESGSLDIMKMLLMYCAKMEKDGYGMTPLLSASVTGHTNIVDFLTHHAQTSKTERINALELLGATFVDKKRDLLGALKYWKKAMNMRYSDRTNIISKPVPQTLIMAYDYAKEVNSAEELEGLIADPDEMRMQALLIRERILGPSHPDTSYYIRYRGAVYADSGNFKRCINLWKYALDMQQSNLDPLSPMTASSLLSFAELFSFMLQDR----AKGLLGTTVTFDDLMGILCKSVLEIER-------------------------------------------AIKQTQCPADP--LQLNKALSIILHLICLLEKVP----CTVEQDHFKKQTIYRFLKLHPRGKNNFSPLHLAVDKNTTCVGRYPVCKFPSLQVTAILIECGADVNVRDSDDNSPLHIAALNNHPD-IMNLLIKSGAHFDATNLHKQTASDLLDEKEIAKNLIQPINHTTLQCLAARVIVNHRIYYKGNIPEKLETFVSLHR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96JP0-1", "uniprot_id": "FEM1C_HUMAN", "id": "Q96JP0-1", "name": "Protein fem-1 homolog C", "aln": "MDLKTAVFNAARDGKLRLLTKLLASKSKEEVSSLISEKTNGATPLLMAARYGHLDMVEFLLEQCSASIEVGGSVNFDGETIEGAPPLWAASAAGHLKVVQSLLNHGASVNNTTLTNSTPLRAACFDGHLEIVKYLVEHKADLEVSNRHGHTCLMISCYKGHKEIAQYLLEKGADVNRKSVKGNTALHDCAESGSLDIMKMLLMYCAKMEKDGYGMTPLLSASVTGHTNIVDFLTHHAQTSKTERINALELLGATFVDKKRDLLGALKYWKKAMNMRYSDRTNIISKPVPQTLIMAYDYAKEVNSAEELEGLIADPDEMRMQALLIRERILGPSHPDTSYYIRYRGAVYADSGNFKRCINLWKYALDMQQSNLDPLSPMTASSLLSFAELFSFMLQDR----AKGLLGTTVTFDDLMGILCKSVLEIER-------------------------------------------AIKQTQCPADP--LQLNKALSIILHLICLLEKVP----CTLEQDHFKKQTIYRFLKLHPRGKNNFSPLHLAVDKNTTCVGRYPVCKFPSLQVTAILIECGADVNVRDSDDNSPLHIAALNNHPD-IMNLLIKSGAHFDATNLHKQTASDLLDEKEIAKNLIQPINHTTLQCLAARVIVNHRIYYKGHIPEKLETFVSLHR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7T3P8-1", "uniprot_id": "FEM1C_DANRE", "id": "Q7T3P8-1", "name": "Protein fem-1 homolog C", "aln": "MDLKTAVFNAARDGKLKLLQKLLENKSDREVLKLMAEKTNGATPLLMASRYGHLELVEFLMECCCAPVELGGSVNFDGEVIEGAPPLWAASAAGHLKVVQSLLGHGASVNNTTLTNSTPLRAACFDGHLDIVRYLVEHQADLEVANRHGHTCLMISCYKGHREIAQFLLEKGADVNRRSVKGNTALHDCAESGSLEIMKMLLKFGASMEKDGYGMTPLLSASVTGHTNIVDFLTAHPQTGLAERISALELLGATFVDKKRDLLGALQYWKRAMELRHSEAD-CMRREEPLEPEPAYDCSREVSTAEELDGLIADPDDMRMQALLIRERILGPAHPDTSYYIRYRGAVYADSGNFERCIRLWKYALDMQQSNLEPLSPMTASSLLSFAELFSFMLQDR----AKGLLGAGVSFQQLMEILCRSVLEIER-------------------------------------------AVKQPRPSPDPDPAQLSKLLSIILHLICLLEKLP----CSPEQDQHKKETIYRFLKLQACGRNGFSPLHLAVDHNTTCVGRYPVCKFPSLQVASVLLECGADVNSRDLDDNSPLHVAASNNHPD-IMKLLISGGTHFDSTNALQQTACDLLDHTQLAKSLIQPINHTTLQCLAARAIIRHRLVYRGSIPERLEAFVLLHR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VFD5-1", "uniprot_id": "FEM1A_DROME", "id": "Q9VFD5-1", "name": "Protein fem-1 homolog CG6966", "aln": "MDYKFIVFNAARDNNLAQLKATLYNKSSVEVGSLISAKVNGATPLVISCRNGHYDIVEYLLTKCRANVEQVGSVSFDGEPIEDAPPLWCAAAAGHLGIVKMLVRRGANVNSTTRTNSTPLRAACFDGHYEIVKYLVHHGADFEVANRHGHTCLMIACYKGHFRIAQYLLSLNADVNRCSVKGNTALHDCAESGSLQILQLLLKHGATMDVDYYGMTPLLAASVTGHMPIVEHLITLPCVSRESRIHALELLGATYVDRKRDMAAALNLWRRALEERAVEPP---LEKKVQEPVPAYEMVREVTSVEELEEMVLDPDEMRMQALVIRQRILGPTHPDTSYYIRFRGAHYADAGRFDRCIELWSYALTMQQKILQPLSPMTQSSLLSFAELFSFMLVEAGRLLPRGRVVPPIEPDSMLTIFYKAVKEVERGLAFTLEQQKDQQHPQKQLPAADKSPSCSASSSASSSSSTTLLSAHQHDCNHDP--NALSRTMISAIHIGCLLSSLLDTDALSPEMRRQVMGALYRLNRLKVRVRFDRTALHYACYREGTLAGRYPSCQFPSVTLAKALLEVGADPNAIDEAGNTPLHLATMQPYVEPLSHILLEGGAHLDTKNYAGETFESLLAPTPMHK-IIDPMKYTTLACLAARTIKKHDIRYEGTVPATLYEFIELH-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** * *******.:* * * .**. ** .*:: *.******:::.* ** ::**:*: * * :* ***.**** **.*****.*:***** :*: *: :**.**.** ************** :**:***.* **:**:**********:***** .***:**. .***** *****************:*:::** . *.*: * *******:****** **:.* . .. .** ********:**:***: .**: *::*:: * : . **: :**.:.***: :: ***:******:**:*****:*********:*** ***:*.*.***.**.*** ***. *:****** ************** : .:* : . : :.:: *: ::* *:** : :* ** *.: : :*: ***..: : * : ::**: :*: : . :.** * :: * .**** *:***: :: *:* *** * * .*:***:*: : : : : ::*:..*:*:*:.* :* .** . : * :*:*:::*** *****.* .* : *.* :* * *: ** ", "identical_positions": 312, "similar_positions": 157, "identity": "46.5%" }, { "cls_id": "homologset.agr.RGD:1309323", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GCV6-1", "uniprot_id": "A0A8I6GCV6_RAT", "id": "A0A8I6GCV6-1", "name": "Tyrosine-protein kinase receptor", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPRLFLFPGSDVSVSRPAGNRRGSGDSSETAGHAYKLQPGSRVASSQPPS-LAGTKRSKDRAMGYSRQLLLCLGAAGIILCSNS------------EFQAPFLTPSPLPVLVLNS------------------------------------------------------------------------------------------QEERIIPTPSRLKPASLPNPLGKRGP---WVINTCGASGRRGPTQTQCDRAYTGNSVMVTVGAAGPLKGVQLWRAPDTGQY-ISAYGAAGGKGARNHLSRAHGIFLSAVFFLSRGEPVYILVGQQGQDACPGGSPESQLVCLGES---GEHETTDGSERVPGWRRWAGGGGGGGGATYIFRLRTGKPEPLLVAAGGGGRSYRRRPERGWTQAAPERLETRAAAQGSGRRGGAAGVRGGWTSRAPSPQAGRSPGEGAEGGEGCAEAWAALRWAAEGGFGGGGGACAAGGGSGGYRGGDTSESDLLWADGEDGISFVHPSGELYLQPLAVTEGDVEVEIRRHPNCSHCSFKDCQWQAELWRAECICPEGMELAVDNITCTGLPT--------------------------------TTSPLIMMGAVVTALTLSLLMMCGVLILVNQKKCQSLRGT--RLPGPELELSKLRTSAIRTAPNPYYCQVGLSPAQAWPLPQGLTEVSPANVTLLRALGHGAFGEVYEGLVIGLPGDSSPLPVAIKTLPELCSPQDELDFLMEALIISKFSHQNIVRCVGLSFQAAPRLILLELMSGGDMKSFLRHSRPHPGQLSPLTMQDLLQLAQDIAQGCHYLEENHFIHRDIAARNCLLSCSGDSRVAKIGDFGMARDIYQASYYRKGGRTLLPVKWMPPEALLEGLFTSKTDSWSFGVLLWEIFSLGYMPYPGHTNQEVLDFIATGNRMDPPRNCPGPVYRIMTQCWQLQPELRPDFASILERIQYCIQDPDVLNSPLPMEPGPIVEEEGASGPG------------NRSLEGLRSPKT--LELSSQNLKS------------------------------RGGDLLGSQLPSGLKTLTSRC----------LQPQNIWNPTYGSWTPR------SPQGEDSDIDLSNGPSSDSFPGEQ---------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P08923-1", "uniprot_id": "LTK_MOUSE", "id": "P08923-1", "name": "Leukocyte tyrosine kinase receptor", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGCSHRLLLWLGAAGTILCSNS------------EFQTPFLTPSLLPVLVLNS------------------------------------------------------------------------------------------QEQKVTPTPSKLEPASLPNPLGTRGP---WVFNTCGASGRSGPTQTQCDGAYTGSSVMVTVGAAGPLKGVQLWRVPDTGQYLISAYGAAGGKGAQNHLSRAHGIFLSAVFFLRRGEPVYILVGQQGQDACPGGSPESQLVCLGES---GEHATTYGTERIPGWRRWAGGGGGGGGATSIFRLRAGEPEPLLVAAGGGGRSYRRRPDRGRTQAVPERLETRAAAPGSGGRGGAAGGGSGWTSRAHSPQAGRSPREGAEGGEGCAEAWAALRWAAAGGFGGGGGACAAGGGGGGYRGGDTSESDLLWADGEDGTSFVHPSGELYLQPLAVTEGHGEVEIRKHPNCSHCPFKDCQWQAELWTAECTCPEGTELAVDNVTCMDLPT--------------------------------TASPLILMGAVVAALALSLLMMCAVLILVNQK-CQGLWGT--RLPGPELELSKLRSSAIRTAPNPYYCQVGLSPAQPWPLPPGLTEVSPANVTLLRALGHGAFGEVYEGLVTGLPGDSSPLPVAIKTLPELCSHQDELDFLMEALIISKFSHQNIVRCVGLSFRSAPRLILLELMSGGDMKSFLRHSRPHPGQLAPLTMQDLLQLAQDIAQGCHYLEENHFIHRDIAARNCLLSCSGASRVAKIGDFGMARDIYQASYYRKGGRTLLPVKWMPPEALLEGLFTSKTDSWSFGVLLWEIFSLGYMPYPGHTNQEVLDFIATGNRMDPPRNCPGPVYRIMTQCWQHQPELRPDFGSILERIQYCTQDPDVLNSPLPVEPGPILEEEEASRLG------------NRSLEGLRSPKP--LELSSQNLKS------------------------------WGGGLLGSWLPSGLKTLKPRC----------LQPQNIWNPTYGSWTPR------GPQGEDTGIEHCNGSSSSSIPGIQ---------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P29376-1", "uniprot_id": "LTK_HUMAN", "id": "P29376-1", "name": "Leukocyte tyrosine kinase receptor", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGCWGQLLVWFGAAGAILCSSP------------GSQETFLRSSPLPLASPSP------------------------------------------------------------------------------------------RDPKVSAPPSILEPASPLNSPGTEGS---WLFSTCGASGRHGPTQTQCDGAYAGTSVVVTVGAAGQLRGVQLWRVPGPGQYLISAYGAAGGKGAKNHLSRAHGVFVSAIFSLGLGESLYILVGQQGEDACPGGSPESQLVCLGESRAVEEHAAMDGSEGVPGSRRWAGGGGGGGGATYVFRVRAGELEPLLVAAGGGGRAYLRPRDRGRTQASPEKLENRSEAPGSGGRGGAAGGGGGWTSRAPSPQAGRSLQEGAEGGQGCSEAWATLGWAAAGGFGGGGGACTAGGGGGGYRGGDASETDNLWADGEDGVSFIHPSSELFLQPLAVTENHGEVEIRRHLNCSHCPLRDCQWQAELQLAECLCPEGMELAVDNVTCMDLHK--------------------------------PPGPLVLMVAVVATSTLSLLMVCGVLILVKQKKWQGLQEM--RLPSPELELSKLRTSAIRTAPNPYYCQVGLGPAQSWPLPPGVTEVSPANVTLLRALGHGAFGEVYEGLVIGLPGDSSPLQVAIKTLPELCSPQDELDFLMEALIISKFRHQNIVRCVGLSLRATPRLILLELMSGGDMKSFLRHSRPHLGQPSPLVMRDLLQLAQDIAQGCHYLEENHFIHRDIAARNCLLSCAGPSRVAKIGDFGMARDIYRASYYRRGDRALLPVKWMPPEAFLEGIFTSKTDSWSFGVLLWEIFSLGYMPYPGRTNQEVLDFVVGGGRMDPPRGCPGPVYRIMTQCWQHEPELRPSFASILERLQYCTQDPDVLNSLLPMELGPTPEEEGTSGLG------------NRSLECLRPPQP--QELSPEKLKS------------------------------WGGSPLGPWLSSGLKPLKSRG----------LQPQNLWNPTYRS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QVU0-1", "uniprot_id": "LTK_DANRE", "id": "F1QVU0-1", "name": "Tyrosine-protein kinase receptor", "aln": "MDYITRQTFVKLALFIFTVLRSSCALLEKAAEDPVHPNPLQSSPAEDSDVSFCDFESPCSWTLSSHSTGGDWFITSAQQHRSSRRDTQPIRDYSTGKSEGHFLLLKPSSSHLSAGRCSFHMTSPVVLSSGPFCHLQLARFQPEPHAGNISAFVKHTDSTDIKPIDLTIKEQESDSSQWEVLEAVIGQLNEPFQVTVQYSACSSHEVGFLAFDSLELKNCVMGDDYVDLGSDCEKYSSLQCHSGGCIEKQRVCDFHTDCPEGEDEGLICSTLPLGSYCSFELGSCGWLAADTQSSWRLVSGQQLIEDTHLLGTTLKNTQGHFLFLKVRGHGDEREALVQSPALPSTISNQDCQLQFSLYRYGDFNGTVLLSVVESGASAPALIWERSGHWKDAWQEITLPITEILNGFHLKVQAFWTSGSKADIALDDISLSAACFDTELNELLHEGLPHDLDFSPLPEPSASEASPITWWFTSCGASGPFGPTQAQCDSAYRNTNVSVVVGKEGPLRGVQMWKVPATNTYKISAYGAAGGKGAKNHNKRSHGVFISATFPLEKGDILYILIGHQGEDACPGRNPQTHKICLGES-----SVIEDGFDSDGSALKWAGGGGGGGGATYIYRMENGQPLPLLIAAGGGGKAYLEDPESSQDQSFREQYENDTTVSGVSGRSGAAGGGGGWSDVSSLSWAGKSLVEGGQGGSSCPEALSVLGWATFGGFGGGGGACSAGGGGGGYRGGDAPLLDDISADGQDGLSFVHPMGKIFLQPLAAMESHGEAEIVVYLNCSHCKTQSCKRDEDTKLILCLCDSDEVLAPDNVTCAGTKHSLCQFINKHLQHNSSPLVCPPLVVPMGSLADGPPSLVFIMAVIVSTVVTGVVLTCASLTLIYYRKKNHLHAVRIRLQSPEYKLSKIRSSTIMTDYNPNYGYFGKAASLS-----ELKEVPRKNITLLRALGHGAFGEVYEGQVLGMNGENTAMQVAIKTLPEICSEQDEMDFLMEALIMSKFSHQNIVRCIGVSLQILPRFILLELMTGGDMKSFLRLNRPRTNHSSSLSMLELLHMARDIALGCRYLEENHFIHRDIAARNCLLTCPGPDRVAKIGDFGMARDIYRASYYRKGGRAMLPVKWMPPEAFLEGIFTCKTDTWSFGVLLWEIFSLGYMPYPCKTNQEVLEFVTGGGRMDPPKSCPGPVYRIMTQCWQHCPEHRPNFTTILERINYCTQDPDVINTPLPVECGPPVEEEGGTVIRPDGSGSMTPLLVARSLSQDASPRASITSVTPQALKPRLQLQRPVHLTQEVGTYRETLEPCWAEPVPASGVCPGPWLQVPEHRPCSRSSSSSGSQKLKNKTKNLWNPTYGSWVLESFGRGKSALCHTQSMPLSCNPTSVSAPSSTSEHTDPVVEVNANVSASPPPSAAPSQTTLTPTAAPSRKSPTGAAGVSLATVMDLAKLQSFPCGNVNYAYDEQSYETESLPVVVSKSLEPSTSSAATSSLVALSQPGSFTHKPLVKRHASYGHEDVRRYTQPEKPTRDRDSGFSLSEDLSVTPV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :*: * * .. : .:: .. ** . .: * *. :. :. ..... * :.:***** ****:*** ** ...* *.** * *:***:*:.* .. * ************:** .*:**:*:** * * *: :***:*:**:***** .*::: :***** * : . :************ ::*:. *: ***:******::* . : . *: *: *. : . * . *.**** .**:. : . **:* **.:**..*.** :.* **: **********:****.*******:. * : ***:** **:** .:::*****. *.. *.** : ***** :.*: : : * * .. ** **:** . ... :.:* .:*:: . .::: *. * *: : : * ** .** :***:*:*:* * ** * .* ..: . :.**. *:***************** * *: *:.:.: ********:** ***:********:*** *******:*:*:: **:******:********* .**: .: :.* * :**::*:*** **:*******************:*.* .***************:*****:*.*::**********:***:**.***:******************* :******:*:. *.*****:.************** ** **.* :****::** *****:*: **:* ** *** : ***. .*:. .::.: **. .* *. * : .* :.:*:***** * ", "identical_positions": 432, "similar_positions": 217, "identity": "28.05%" }, { "cls_id": "homologset.agr.RGD:1309325", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZES2-1", "uniprot_id": "D3ZES2_RAT", "id": "D3ZES2-1", "name": "Trafficking protein particle complex subunit 6B", "aln": "--------------------------------------MADEALFLLLHNEMV-------------------------------------------------SGVYKSAEQGEVENGRCITKLENMGFRVGQGLIERFTKDTA-----RFKDELDIMKFICKDFWTTVFKKQIDNLRTNHQGIYVLQDNKFR----LLIQLSAGKQYLEHASKYLAFTCGLIRGGLSNLGIKS-------------IVTAEVSSMPACKFQVMIQKL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D289-1", "uniprot_id": "TPC6B_MOUSE", "id": "Q9D289-1", "name": "Trafficking protein particle complex subunit 6B", "aln": "--------------------------------------MADEALFLLLHNEMV-------------------------------------------------SGVYKSAEQGEVENGRCVTKLESMGFRVGQGLIERFTKDTA-----RFKDELDIMKFICKDFWTTVFKKQIDNLRTNHQGIYVLQDNKFR----LLIQLSAGKQYLEHASKYLAFTCGLIRGGLSNLGIKS-------------IVTAEVSSMPACKFQVMIQKL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86SZ2-1", "uniprot_id": "TPC6B_HUMAN", "id": "Q86SZ2-1", "name": "Trafficking protein particle complex subunit 6B", "aln": "--------------------------------------MADEALFLLLHNEMV-------------------------------------------------SGVYKSAEQGEVENGRCITKLENMGFRVGQGLIERFTKDTA-----RFKDELDIMKFICKDFWTTVFKKQIDNLRTNHQGIYVLQDNKFR----LLTQMSAGKQYLEHASKYLAFTCGLIRGGLSNLGIKS-------------IVTAEVSSMPACKFQVMIQKL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QMV3-1", "uniprot_id": "TPC6B_DANRE", "id": "F1QMV3-1", "name": "Trafficking protein particle complex subunit 6b", "aln": "--------------------------------------MADEALFQFLHSEII-------------------------------------------------QYVN-SAETGESENGRCVSKLENMGFRVGQGLIERFTKDTP-----RFKDELDVMKFICKDFWTSVFKKQIDNLRTNHQGIYVLQDNKFR----LLTQLSAGKQYLEHAPKFLAFTCGLVRGALSNIGVKS-------------IVTAEVSVMPACKFQVMIQKM-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VF82-1", "uniprot_id": "Q9VF82_DROME", "id": "Q9VF82-1", "name": "Trafficking protein particle complex subunit 6B", "aln": "--------------------------------------MSEEILFDCLHAEIV-------------------------------------------------NYCLDSNKEHD------LATLEYIGFTTGYRLIERLTREVS-----RFKDELETMKFICTDFWMLIYKKQVDNLRTNNHGMYVVQDKAFR----FLTRISPGTKQLEHAPKFVAFTCGLVRGALSNLGINS-------------TVTAEVQSIPACKFHIEVNRN-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q99394-1", "uniprot_id": "TRS33_YEAST", "id": "Q99394-1", "name": "Trafficking protein particle complex subunit 33", "aln": "MSSTHSNNVGHPQSSPQGPLTEQQRAQQQYQIFENSLPKVSQSVYQMLLNEMVPLAMGIERQISGDVISSDSNVTSENGNINNMIKRLKIEEHHTVDIIRSHNLIHELYKADEEEKEKVLARLRNIGFQIGLKLSELLIFSNNPNLKFKEMDLLLIMKFICRDVWKQIFGKQIDNLKTNHRGTFYLLDYDYRPIQSFSLEEDAKNEELKMIEPFLEIPVGIIRGVLSSLGYSSEEVICLASFIDRPTDRPKTAFPKGVSFHVQVTMPQ", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: :: * *:: . : : :: *. :** * * * : . : * * ***** *.* :: **:***:**::* : : * :* : . .. .: *: :: :. *::** **.:* .* .:. . .*:: : ", "identical_positions": 36, "similar_positions": 50, "identity": "13.43%" }, { "cls_id": "homologset.agr.RGD:1309327", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9UKK6-1", "uniprot_id": "NXT1_HUMAN", "id": "Q9UKK6-1", "name": "NTF2-related export protein 1", "aln": "-MASVDFKTYVDQACRAAEEFVNVYYTTMDKRRRLLSRLYMGTATLVWNGNAVSGQESLSEFFEMLPSSEFQISVVDCQPVHDEATPSQTTVLVVICGSVKFEGNKQRDFNQNFILTAQASPSN--TVWKIASDCFRFQDWAS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9QZV9-1", "uniprot_id": "NXT1_MOUSE", "id": "Q9QZV9-1", "name": "NTF2-related export protein 1", "aln": "-MASVDFKTYVDQACRAAEEFVNVYYTTMDKRRRLLSRLYMGTATLVWNGNAVSGQESLSEFFEMLPSSEFQISVVDCQPVHDDATPSQTTVLVVICGTVKFEGNKQRDFNQNFILTAQASPSN--TVWKIASDCFRFQDWAS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B2RZ65-1", "uniprot_id": "B2RZ65_RAT", "id": "B2RZ65-1", "name": "NTF2-related export protein", "aln": "-MASVDFKTYVDQACRAAEEFVNVYYTTMDNRRRLLSRLYMGTATLVWNGNAVSGQESLSEFFEMLPSSEFQINVVDCQPVHDEATPSQTTVLVVICGTVKFEGNKQRDFNQNFILTAQASPSN--TVWKIASDCFRFQDWAS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9QCN6-1", "uniprot_id": "E9QCN6_DANRE", "id": "E9QCN6-1", "name": "NTF2-related export protein", "aln": "MSLTVDFRTQVDQSCRYSEEFINIYYECMDKKRRNLKRLYLDKATLVWNGNAVTGQEALGEFFESLPSSEFQVQTLDCQPVHEQATQGQTTLLVVAAGSVKFEGNKQRFFNQNFLLTAQASPNSDQPVWKIASDCFRFQDWAN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V3H8-1", "uniprot_id": "NXT1_DROME", "id": "Q9V3H8-1", "name": "NTF2-related export protein", "aln": "--MDSDLKAKVESCARTADTFTRLYYASVDNRRQQIGRLYLDNATLSWNGNGAIGRQMIESYFQELPSSNHQLNTLDAQPIVDQAVSNQLAYLIMASGSVKFADQQLRKFQQTFIVTAEN------DKWKVVSDCYRMQEV--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *::: *:...* :: * .:** :*::*: : ***:..*** ****.. *:: : .:*: ****:.*:..:*.**: ::*. .* : *:: .*:*** .:: * *:*.*::**: **:.***:*:*: ", "identical_positions": 48, "similar_positions": 57, "identity": "33.57%" }, { "cls_id": "homologset.agr.RGD:1309328", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q6NZC7-1", "uniprot_id": "S23IP_MOUSE", "id": "Q6NZC7-1", "name": "SEC23-interacting protein", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MADRKANGG-------------------------------------------------------------------------GASASSSGTNLLFSSSATEFSFNVPFIPVTQAAASPASLLLPGEDSTDVGE----------------EDSFLGQTSTHTSTPQTFSYFSQVSSSSDPFGNIGQS-------------------------------------------PLTTSAMSAGQSA-------------LPKPPATLAFTTGSQDALSAFPPS-----------VSKAP-GATPPSQMGTSTYSPSQ----------------------------------------------------------------PSSLPPN-FGSPPQGIPQQG----------------------------------------------------------------------------------------------------------------HNPYRHTPVSSRANPYITP-------PQLQQCQMPGH---------------------------------------------------------------------------------------------SSYPPP--------------------------SGPPVQTYQMPPG--------------------------------------PLPPLPTAMQSPAQQQVPARP-------------------------------AGPLVQGPSPFVLQN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QYEPVQPHWFYCKEVEYKQLWMPFSVLDSLNLEEIYNSVQPDPESVVLGTDGGRYDVYLYDRMRKSVYWEEEPTEVRRCTWFYKGDTDSRFIPYTEEFSEKLEAEYKKAVSTN---QWHRRLEFPSGETIVMHNPKVIVQFQPSSVPDEWGTTQDGQTRPRVVKRGIDDSLDEIPDGEMPQVDHLVFMVHGIGPVCDLRFR--SIIECVDDFRVVSLKLLQT-----HFKKSVDEGKVSRVEFLPVHWHSALGGHATGVDRNIKKITLPSIG--------RFRHFTNETLLDVLFYNSPTYCQAIVEKVEVEINRLHSLFMSRNPNFKGKVSVAGHSLGSLILFDILSNQRDMCVSKSPGSVAVSNGVIKHSQFQEKLISEESKLMSDESCDLDVEDEEPLTLHGTLEALSLFDYISTFEKEKIDMESLLMCTVDDLKEMGIPLGPRKKIANFVKLKAAKLEQKKAAAEKKAALAALTKGQDESAPKTKEMASPSSESNESKRKLSVGAYVSSVRVDYESFEVGTGQVSVAYSSLDFEPEIFFALGSPIGMLLTIRGVARID-----------EKYRLPTCKGFFNIYHPLDPVAYRLEPMIAPDLD-LKAVLVPHHKGRKRLHLELKESLSRMGSDLKQGFISSLKSAWQTLNEFARAHTSTTQLQEELEKVANQIKEEEEKQVVEAK--------------KKKESPELSKDEDYLG---KVGMLNGGRRIDYVLQEKPIESFNEYLFALQSHLCYWGSEDTALLLLKEIYRTMNISPEQPQH-----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3V8Q8-1", "uniprot_id": "G3V8Q8_RAT", "id": "G3V8Q8-1", "name": "SEC23-interacting protein", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MADRKANGG-------------------------------------------------------------------------GASASSSGTNLLFSSSATEFSFNVPFIPVTQAAASPASLLLPGEDSTDVGE----------------EDSFLGQTSTHTSTPQTFSYFSQVSSSSDPFGNIGQS-------------------------------------------PLATTAMSAGQSA-------------LPKPPATLPFTTGSQDMLNAFPPS-----------VSKAPYGAAPSSQMGASTYLPSQ----------------------------------------------------------------PSSLPPN-FGSPPQGIPQQG----------------------------------------------------------------------------------------------------------------HNPYRHTPVSSRANPYITP-------PQLQQCQTPGH---------------------------------------------------------------------------------------------PSYPPP--------------------------SAPPVQTYQMPPG--------------------------------------PLPPLPTAVQSPAQQQVPARP-------------------------------AGPLVQGPSPFVLQN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QYEPVQPHWFYCKEVEYKQLWMPFSVLDSLNLEEIYNSVQPDPENVVLGTDGGRYDVYLYDRMRKSVYWEEEPAEVRRCTWFYKGDTDSRFIPYTEEFSEKLEAEYKKAVTTN---QWHRRLEFPSGETIVMHNPKVIVQFQPSSVPDEWGTTQDGQTRPRVVKRGIDDNLDEIPDGEMPQVDHLVFMVHGIGPVCDLRFR--SIIECVDDFRVVSLKLLQT-----HFKKSVDEGKVSRVEFLPVHWHSALGGHATGVDRNIKKITLPSIG--------RFRHFTNETLLDVLFYNSPTYCQSIVEKVGVEINRLHSLFMSRNPNFKGKVSVAGHSLGSLILFDILSNQKDMSISKSPGSVAVSNGVTKHSNFQEKQVSEESKLMSDESCDLDVEDEEPLTLHGTLEALSLFDYISTFEKEKIDMESLLMCTVDDLKEMGIPLGPRKKIANFVKLKAAKLEQKKAASEKKAALAALTKGQGESAPKTKEMASPSSESNESKRKLSVGAYVSSVRVDYESFEVGTGQVSVAYSSLDFEPEIFFALGSPIGMFLTIRGVDRID-----------ESYRLPTCKGFFNIYHPLDPVAYRLEPMIAPDLD-LKAVLIPHHKGRKRLHLELKESLSRMGSDLKQGFISSLKSAWQTLNEFARAHTSSTQLQEELEKVANQIKEEEEKQVVEAE--------------KIVESPEFSKDEDYLG---KVGMLNGGRRIDYVLQEKPIESFNEYLFALQSHLCYWESEDTALLLLKEIYRTMNISPEQPQH-----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y6Y8-1", "uniprot_id": "S23IP_HUMAN", "id": "Q9Y6Y8-1", "name": "SEC23-interacting protein", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAERKPNGGSG-----------------------------------------------------------------------GASTSSSGTNLLFSSSATEFSFNVPFIPVTQASASPASLLLPGEDSTDVGE----------------EDSFLGQTSIHTSAPQTFSYFSQVSSSSDPFGNIGQS-------------------------------------------PLTTAATSVGQSG-------------FPKPLTALPFTTGSQDVSNAFSPS-----------ISKAQPGAPPSSLMGINSYLPSQ----------------------------------------------------------------PSSLPPSYFGNQPQGIPQPG----------------------------------------------------------------------------------------------------------------YNPYRHTPGSSRANPYIAP-------PQLQQCQTPGP---------------------------------------------------------------------------------------------PAHPPP--------------------------SGPPVQMYQMPPG--------------------------------------SLPPVPSSVQSPAQQQVPARP-------------------------------GAPSVQVPSPFLLQN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QYEPVQPHWFYCKEVEYKQLWMPFSVFDSLNLEEIYNSVQPDPESVVLGTDGGRYDVYLYDRIRKAAYWEEEPAEVRRCTWFYKGDTDSRFIPYTEEFSEKLEAEYKKAVTTN---QWHRRLEFPSGETIVMHNPKVIVQFQPSSVPDEWGTTQDGQTRPRVVKRGIDDNLDEIPDGEMPQVDHLVFVVHGIGPVCDLRFR--SIIECVDDFRVVSLKLLRT-----HFKKSLDDGKVSRVEFLPVHWHSSLGGDATGVDRNIKKITLPSIG--------RFRHFTNETLLDILFYNSPTYCQTIVEKVGMEINHLHALFMSRNPDFKGGVSVAGHSLGSLILFDILSNQKDLNLSKCPGPLAVANGVVKQLHFQEKQMPEEPKLTLDESYDLVVENKEVLTLQETLEALSLSEYFSTFEKEKIDMESLLMCTVDDLKEMGIPLGPRKKIANFVEHKAAKL--KKAASEKKAVAATSTKGQEQSAQKTKDMASLPSESNEPKRKLPVGACVSSVCVNYESFEVGAGQVSVAYNSLDFEPEIFFALGSPIAMFLTIRGVDRID-----------ENYSLPTCKGFFNIYHPLDPVAYRLEPMIVPDLD-LKAVLIPHHKGRKRLHLELKESLSRMGSDLKQGFISSLKSAWQTLNEFARAHTSSTQLQEELEKVANQIKEEEEKQVVEAE--------------KVVESPDFSKDEDYLG---KVGMLNGGRRIDYVLQEKPIESFNEYLFALQSHLCYWESEDTALLLLKEIYRTMNISPEQPQH-----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VLS7-1", "uniprot_id": "Q9VLS7_DROME", "id": "Q9VLS7-1", "name": "", "aln": "MSERSKGDVSARVNNNANQTRVVKNPLLSASVTGLSFDDFPNKPQLLPAAPPVVHATPPAAPVLIAGILNREPKSLVTVGQPSSIDDSEALDEINLNTSSEDSVGAGGSSPYLGAGDQNANPLLEPPTEAGNDSLLSQAASSFTALPAVASNVFSTFSKRIYAGSRETSEEPKLDIQPSYIQQASYVQPVAPVPAPFYAAPPAAANEVVAPEPPKFYAPTEVPPPNVGVPAPPPTSGNPNTYRFTARKKLYAPIPGLSEQSGQPAQQPQVPQAPQAAPSFQTPPYPPQLTYAANPAPFDISAQPAAIPAEERKSGGGLFSLTSLVPTGVLQNITGIVQSATGRSSEPEHTNVQQAGGYLDITTASAPAPSTNLFGGPNSTFPPGGNYFVPGAPPSLPSTGVVGPPSVGNFFAPAAPLPVAQTAAPPAVGAFFTSAAPSVTPSVFTPGTVPPLAPQPFQSATVNQSALPPNNPPTASAVGELFVPAPTTIAQGTSPAVPFVDTQAVPTIPLTVPPGNPPPTSTLGGFFTTGEVAPVVAPFGTQASPATQSAGFFNPGEVRPNVPLAEPVPTIPITSSGVPPIGLFPPAPAQPGVQTASNPNPLPGAAAPPPAAGQASYRLQKGTRLYKSPLTPQETATSSGFAAPLPPTSVTPAIFNPFGAPAPGSFNSVGHLEGQSSQGVPFFTPPVQNPPGQVAAPTVAVPQSAPIAPPPGTSSTSVAPPLTASIANPPPTSGFASVPLFAAPTISSTPIPFFNPQPTGAEVTTGLSQQENEATASTTLEGLVQGPAPTLSASQFFDTPLPTGTQPENQVASVSSERENLVQEPISNQGIPFFAPPQTNIFTPQLQQEFIAPAEDSKRSEIQEEFLSAPPQESNLSTELREDTHTGPPVIEPVLEETPASSSESSVPPASKVDQEDIVYPEPSAPVEQEIPLFVPVPGLPGLSQDIPLYPPPPTGSTTASSIFAAPPVASSAPLFVPVPGPPSVSSLFSPSQVDSTSSLFAPPPTSANTTILTPAPDTTSTLFANNIPTTTPSIPDIVPTTSAELVDAPPGFQGSSDDTATNLFQGNTETQTVFSPFAQTKATPLVQETKPELVPPPIGFFAPKSESEVLSQPPLAPSPLQSFFSTAPETATTTDFNFFGSPAPGSVFPDLPVQQGIAPPPLALESPPQNSVSNIATSAIGFDLLNQTQQASSLVENSNQNSSVNSFDGYFGGPSASAAQTFANETTNALVAPAINCDPVNFFDQVPQTQSQIQQANEDQRIQNFFNNPPLQDQPAVPGELKYDIVHSGVAVKQLQERSQTPVSNLVEPPSSACSEFSTLAPAPTQTDRQSGDDLLQQHLGELPEDILRELRMASASSEKGQVATPPVAIPYSPVVAHWFYKRSVDTKFIWTPFSHYDSALLETSLN---LDDSTLIIPVEGGRYDVNIKERTKTPVYWEGKAIEVRRCSWFYKG-VDSKYVPYTEDTAALLEAEYKRSAETG---EWHQKIMLANGEQVVFHGPTVIVHFLPQQNADTWGASTQGSMRPRVVKRDLDD--FTIEQGESQRVDHLLFMVHGIGSACDLKMR--SVEEVVDDFRVIAQQLVQS-----HYKNSTDMGLVGRVEVLPISWHGHLHSEELGIDEKLKSITLESIP--------RLRNFTNDTLLDVLFYTSPKYCQKIMNTVADALNDVYLKYRMRHPEFNGGVSLAGHSLGSLILFDLLCHQEPLKESE--------------------------------------------------------------------------------------------------------------------------------EENKENPDQLPQKQSSQKVQLPTSDPLPKQVSYAMGPEGTGQPVITYTQLIFHPKKFFALGSPIGMFVTIRGIDKLG-----------LDFHLPTCPGFYNIFHPFDPVAYRIEALVNPDMNGIRPVLIPHHKGRKRMHLELKETMTRVGADIKQRFMDTFKTTLDSVNFLTTVTKVKKEAEESLEKETSQTSSQAFQKQTEDQDESSVASSSCKLRNRTDSNSTTASDPEFIELDFPLGKLNDSKRVDYVLQEAPLEFINEYIFALSSHVCYWGSEDTILFVMKEIYASLGISTDSQVPQSSMTIERPVSHESSVSHSLLPM", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12204-1", "uniprot_id": "YOR22_YEAST", "id": "Q12204-1", "name": "Probable phospholipase YOR022C, mitochondrial", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLRFTHRGLPSSTRFRNIFVRLNHIYVP---------WFYAIDVPNSKP--------------------YLPTYQTLHSPKKFKPFSVDDSNR-----------------------------------------------------LEKASKRQERRP------------VLVNEDYLFKVDLSHMELSPTYWEG--------------------PTYQVRRGVWFDSS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NQPLSSDLTSEIEG-----LYKQLKFDDSNDD---------------------------------------------------------------------------------------------PTTTPP---------------------------AESQDIFRLKG------------------------------------------KYPVDKENEGEQKNGSSN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KDENESTFKFILFANKQTAFLLSDLDG--GKLQLAFLRSNLAQSLPINATMITRSYKYSSSATTKQTSTSFKAAKTPQTEVADGSNSSKSRSIETKLEKKVSNLFNLSDFLQLFNGNASKDQDDAQSLEKQMETDYNNADNSQGANASSKIEDGKNSGASDRQIRSNRRDVDNLILCVHGIGQTLGKKYEYVNFAHTVNLLRSNMKKIYNNSEKLQSLNTAPDYKSNCNVQVLPITWRHSISFQTDAKEENIENPDLPTLSQVTVNGVLPLRKLLADGLLDILLYVEPYYQDMILQQVTSQLNKTYRIFKEFNPEFDGKVHLVGHSLGSMILFDILSKQK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KYELEFQVDNLFFIGSPIGLLKLIQRTKIGDRPEFPNDLERKLTVQRPQCKDIYNVYHVCDPISYRMEPLVSKEMAHYEQTYLPHCSEAYGLTSKVLEFGENIWKDLPG----------TDENNLQSKKTSPEKKEVKLSENLTRMLTG----------------------------------------------LNYTGRLDYAMSPSLLEVD--FISAIKSHVSYFEEPDIAAFILKEILSKHENASEIYVKRKTG-------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .: .. :: : *. : .. : * . . .. : . : : : : : . . : . *. : .. : * *. . : **: . .** . . : * . . : : . : . : *: :: * : . . .: : .: . :. .. : .: * . . . :. .: : . * * .. : : : .*: :. :. . : . : .. .:: . .. .: **:*:: ***** . . : . .. . *: :* :: .. :.: * .*:.**: *: : . . :.:::. * :: :*:: : ***:*:* .* * : *:: * :* : : :*:*.* * :.******:****:*.:*. .* *. . :* :****.:: *: . * * .::*::* **::**:*.:: :: . . :** . : :: * .: *: * : . : : .*.: .: ** *:**.:. :* :: *:.**:.*: . * :::*** . :.: ", "identical_positions": 96, "similar_positions": 223, "identity": "4.41%" }, { "cls_id": "homologset.agr.RGD:1309329", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "F1MAD0-1", "uniprot_id": "F1MAD0_RAT", "id": "F1MAD0-1", "name": "Low-density lipoprotein receptor-related protein", "aln": "------------------------------METAPTRAPPPPPQPLLLLLALCC--------------SLVPAAASP----------LLLFANRRDVRLVDAG--GVKLESTIVASGLEDAAAVDFQFSKGAVYWTDVSEEAIKQTYLNQTG--------AAAQNIVISGLVSPDGLACDWVGKKLYWTDSETNRIEVANLNGTSRKVLFWQDLDQPRAIALDPAHGYMYWTDWGEAPRIERAGMDGS--TRKIIVDSDIYWPNGLTIDLEEQKLYWADAKLSFIHRANLDGSFRQKVVEGSLTHPFALTLSGDTLYWTDWQTRSIHACNKWTGEKRKEILSALYSPMDIQVLSQERQPHFHTPCEEGNGGCSHLCLLSPREPFYSCACPTGVQLQDNGKTCKAGAEEVLLLARRTDLRRISLDTPDFTDIVLQVGDIRHAIAIDYDPLEGYVYWTDDEVRAIRRAYLDGSGAQTLVNTEINDPDGIAVDWVARNLYWTDTGTDRIEVTRLNGTSRKILVSEDLDEPRAIVLHPVMGLMYWTDWGE-NPKIECANLDGRDRHVLVNTSLGWPNGLALDLQEGKLYWGDAKTDKIEVINIDGTKRQTLLEDKLPHIFGFTLLGDFIYWTDWQRRSIERVHKVKAS-RDVIIDQLPDLMGLKAVNVAKVVGTNPCADGNGGCSHLCFFTPHATKCGCPIGLELLSDMKTCIIPEAFLVFTSRATIHRISLETN---NNDVAIPLTGVKEASALDFDVSNNHIYWTDVSLKTISRAFMNGSSVEHVIEFGLDYPEGMAVDWMGKNLYWADTGTNRIEVARLDGQFRQVLVWRDLDNPRSLALDPTKGYIYWTEWGGKPRIVRAFMDGTNCMTLVDKVGRANDLTIDYADQRLYWTDLDT-NMIESSNMLGQER-MVIADDLPYPFGLTQYSDYIYWTDWNLHSIERADKTSGRNRTLIQGHLDFVMDILVFHSSRQDGLNDCVHSNGQCGQLCLAIPG--GHRCGCASHYTLDPSSRNCSPPSTFLLFSQKFAISRMIPDDQLSPDLILPLHGLRNVKAINYDPLDKFIYWVDGR-QNIKRAKDDGTQPSMLTSPSQSLSPDRQPHDLSIDIYSRTLFWTCEATNTINVHRLDGDAMGVVLRGDRDRPRAIAVNAERGYMYFTNMQDHAAKIERASLDGTEREVLFTTGLIRPVALVVDNALGKLFWVDADLKRIESCDLSGANRLTLEDANIVQPVGLTVLGRHLYWIDRQQQMIERVEKTTGDKRTRVQGRVTHLTGIHAVEEVSLEEFSAHPCARDNGGCSHICIAKGDGTPR----CSCPVHLVLLQNLLTCGEPPTCSPDQFACAT-------GEIDCIPGAWRCDGFPECADQSDEEGCPVCSASQFPCARGQCVDLRLRCDGEADCQDGSDEANCDAVCLPNQFRCAS-GQCVLIKQQCDSFPDCADGSDE---LMCEINKPPSDDVPAHSSAIGPVIGIILSLFVMGGVYFVCQRVMCQRYTGASGPFPHEYVGGTPHVPLNFIAPGGSQHGPFPGIPCSKSMMSSVSLVGGRGS-VPLYDRNHVTGASSSSSSSTKATLYPPILNPPPSPATDPSLYNMDMFYSSNIPSTARPYRPYIIRGMAPPTTPCSTDVCDSDYSTSRWKTSK----------------YYLDLNSDSDPYPPPPTPHSQYLS-----AEDSCPPSPVTERS-YCHLFPPPPSPCTDSS----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91VN0-1", "uniprot_id": "LRP5_MOUSE", "id": "Q91VN0-1", "name": "Low-density lipoprotein receptor-related protein 5", "aln": "------------------------------METAPTRAPPPPP-PPLLLLVLYC--------------SLVPAAASP----------LLLFANRRDVRLVDAG--GVKLESTIVASGLEDAAAVDFQFSKGAVYWTDVSEEAIKQTYLNQTG--------AAAQNIVISGLVSPDGLACDWVGKKLYWTDSETNRIEVANLNGTSRKVLFWQDLDQPRAIALDPAHGYMYWTDWGEAPRIERAGMDGS--TRKIIVDSDIYWPNGLTIDLEEQKLYWADAKLSFIHRANLDGSFRQKVVEGSLTHPFALTLSGDTLYWTDWQTRSIHACNKWTGEQRKEILSALYSPMDIQVLSQERQPPFHTPCEEDNGGCSHLCLLSPREPFYSCACPTGVQLQDNGKTCKTGAEEVLLLARRTDLRRISLDTPDFTDIVLQVGDIRHAIAIDYDPLEGYVYWTDDEVRAIRRAYLDGSGAQTLVNTEINDPDGIAVDWVARNLYWTDTGTDRIEVTRLNGTSRKILVSEDLDEPRAIVLHPVMGLMYWTDWGE-NPKIECANLDGRDRHVLVNTSLGWPNGLALDLQEGKLYWGDAKTDKIEVINIDGTKRKTLLEDKLPHIFGFTLLGDFIYWTDWQRRSIERVHKVKAS-RDVIIDQLPDLMGLKAVNVAKVVGTNPCADGNGGCSHLCFFTPRATKCGCPIGLELLSDMKTCIIPEAFLVFTSRATIHRISLETN---NNDVAIPLTGVKEASALDFDVSNNHIYWTDVSLKTISRAFMNGSSVEHVIEFGLDYPEGMAVDWMGKNLYWADTGTNRIEVARLDGQFRQVLVWRDLDNPRSLALDPTKGYIYWTEWGGKPRIVRAFMDGTNCMTLVDKVGRANDLTIDYADQRLYWTDLDT-NMIESSNMLGQER-MVIADDLPYPFGLTQYSDYIYWTDWNLHSIERADKTSGRNRTLIQGHLDFVMDILVFHSSRQDGLNDCVHSNGQCGQLCLAIPG--GHRCGCASHYTLDPSSRNCSPPSTFLLFSQKFAISRMIPDDQLSPDLVLPLHGLRNVKAINYDPLDKFIYWVDGR-QNIKRAKDDGTQPSMLTSPSQSLSPDRQPHDLSIDIYSRTLFWTCEATNTINVHRLDGDAMGVVLRGDRDKPRAIAVNAERGYMYFTNMQDHAAKIERASLDGTEREVLFTTGLIRPVALVVDNALGKLFWVDADLKRIESCDLSGANRLTLEDANIVQPVGLTVLGRHLYWIDRQQQMIERVEKTTGDKRTRVQGRVTHLTGIHAVEEVSLEEFSAHPCARDNGGCSHICIAKGDGTPR----CSCPVHLVLLQNLLTCGEPPTCSPDQFACTT-------GEIDCIPGAWRCDGFPECADQSDEEGCPVCSASQFPCARGQCVDLRLRCDGEADCQDRSDEANCDAVCLPNQFRCTS-GQCVLIKQQCDSFPDCADGSDE---LMCEINKPPSDDIPAHSSAIGPVIGIILSLFVMGGVYFVCQRVMCQRYTGASGPFPHEYVGGAPHVPLNFIAPGGSQHGPFPGIPCSKSVMSSMSLVGGRGS-VPLYDRNHVTGASSSSSSSTKATLYPPILNPPPSPATDPSLYNVDVFYSSGIPATARPYRPYVIRGMAPPTTPCSTDVCDSDYSTSRWKSSK----------------YYLDLNSDSDPYPPPPTPHSQYLS-----AEDSCPPSPGTERS-YCHLFPPPPSPCTDSS----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75197-1", "uniprot_id": "LRP5_HUMAN", "id": "O75197-1", "name": "Low-density lipoprotein receptor-related protein 5", "aln": "------------------------------MEAAPPGPPWPLLLLLLLLLALCG--------------CPAPAAASP----------LLLFANRRDVRLVDAG--GVKLESTIVVSGLEDAAAVDFQFSKGAVYWTDVSEEAIKQTYLNQTG--------AAVQNVVISGLVSPDGLACDWVGKKLYWTDSETNRIEVANLNGTSRKVLFWQDLDQPRAIALDPAHGYMYWTDWGETPRIERAGMDGS--TRKIIVDSDIYWPNGLTIDLEEQKLYWADAKLSFIHRANLDGSFRQKVVEGSLTHPFALTLSGDTLYWTDWQTRSIHACNKRTGGKRKEILSALYSPMDIQVLSQERQPFFHTRCEEDNGGCSHLCLLSPSEPFYTCACPTGVQLQDNGRTCKAGAEEVLLLARRTDLRRISLDTPDFTDIVLQVDDIRHAIAIDYDPLEGYVYWTDDEVRAIRRAYLDGSGAQTLVNTEINDPDGIAVDWVARNLYWTDTGTDRIEVTRLNGTSRKILVSEDLDEPRAIALHPVMGLMYWTDWGE-NPKIECANLDGQERRVLVNASLGWPNGLALDLQEGKLYWGDAKTDKIEVINVDGTKRRTLLEDKLPHIFGFTLLGDFIYWTDWQRRSIERVHKVKAS-RDVIIDQLPDLMGLKAVNVAKVVGTNPCADRNGGCSHLCFFTPHATRCGCPIGLELLSDMKTCIVPEAFLVFTSRAAIHRISLETN---NNDVAIPLTGVKEASALDFDVSNNHIYWTDVSLKTISRAFMNGSSVEHVVEFGLDYPEGMAVDWMGKNLYWADTGTNRIEVARLDGQFRQVLVWRDLDNPRSLALDPTKGYIYWTEWGGKPRIVRAFMDGTNCMTLVDKVGRANDLTIDYADQRLYWTDLDT-NMIESSNMLGQER-VVIADDLPHPFGLTQYSDYIYWTDWNLHSIERADKTSGRNRTLIQGHLDFVMDILVFHSSRQDGLNDCMHNNGQCGQLCLAIPG--GHRCGCASHYTLDPSSRNCSPPTTFLLFSQKSAISRMIPDDQHSPDLILPLHGLRNVKAIDYDPLDKFIYWVDGR-QNIKRAKDDGTQPFVLTSLSQGQNPDRQPHDLSIDIYSRTLFWTCEATNTINVHRLSGEAMGVVLRGDRDKPRAIVVNAERGYLYFTNMQDRAAKIERAALDGTEREVLFTTGLIRPVALVVDNTLGKLFWVDADLKRIESCDLSGANRLTLEDANIVQPLGLTILGKHLYWIDRQQQMIERVEKTTGDKRTRIQGRVAHLTGIHAVEEVSLEEFSAHPCARDNGGCSHICIAKGDGTPR----CSCPVHLVLLQNLLTCGEPPTCSPDQFACAT-------GEIDCIPGAWRCDGFPECDDQSDEEGCPVCSAAQFPCARGQCVDLRLRCDGEADCQDRSDEADCDAICLPNQFRCAS-GQCVLIKQQCDSFPDCIDGSDE---LMCEITKPPSDDSPAHSSAIGPVIGIILSLFVMGGVYFVCQRVVCQRYAGANGPFPHEYVSGTPHVPLNFIAPGGSQHGPFTGIACGKSMMSSVSLMGGRGG-VPLYDRNHVTGASSSSSSSTKATLYPPILNPPPSPATDPSLYNMDMFYSSNIPATARPYRPYIIRGMAPPTTPCSTDVCDSDYSASRWKASK----------------YYLDLNSDSDPYPPPPTPHSQYLS-----AEDSCPPSPATERS-YFHLFPPPPSPCTDSS----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QTJ4-1", "uniprot_id": "F1QTJ4_DANRE", "id": "F1QTJ4-1", "name": "", "aln": "------------------------------MELKPG---ALAMEILLLELLLCC--------------SLTVIRGSP----------LLLFANRRDVRLVDVE--VGRSESAVVVSDLEDAAAVDFLFSEGLIFWTDVSEEAIKQTYYNLSTNSMKEATLGKGQTVVVSGLDSPDGLACDWLGHKLYWTDSETNRIEVANLDGTSRKVLFWQDLDQPRAIALNPSHRYMYWTDWGEEPRIERAGMDGS--NRQIIVQKQIYWPNGLTIDLDEQKLYWADAKLSFIHRANLDGTSREAVVEGSLTHPFALTLYDETLYWTDWQTRSIHACNKHSGEKHREILNGIYSPMDIQVLGQERQPNIQTPCSERNGGCSHLCLLSPIPPFYSCACPTGVKLKEDGKTCRPGAEQVLLLARRTDLRRISLDLPDFTDIVLQVNDIRHAIAIDYDPVEGYVYWTDDELRAIRRARIDGSDAQTLITNEINHPDGIAVDWVARNLYWTDTGTDRIEVTRLNGTSRRVLISENLDEPRAIVLDPINGYMYWTDWGE-LPKIERANLDGTDRVVLLNTSLGWPNGLAIDYIAGKLYWGDAKTDKIEVINVDGTNRMTILEDKLPHIFGFTLLGEYIYWTDWQRRSIERVHIANST-REVIVEQLPDLMGLKATKVMEAEGTNGCAENNGGCSHLCFHRPQGLSCACPMGLELLSDLRTCVVPEAFLLFTNRADIRSISLGTN---SNDVPIPLTGVKEASALDFDVLENRIYWTDVSTKTISRAFMNGSSVEPVIEFGLDYPEGMAVDWMGRNLYWADTGTNRIEVARLDGQYRQVLVCKDLDNPRSLALDPANGYMYWTEWGGRPRIARAHMDGSNIVTLVDKVGRANGLTIDYIDQRLYWTDLDT-CMIESTNMQGLQR-EIVADDLPHPFGLTQYRDYIYWTDWNLRSIERADKRSGLNRTVVQGHLEYVMDILVFHSSRQDGANDCSQNNGQCAHLCLASPS--GAQCRCASHYTLEANGRNCSSPSSFLLFSQKSSISRMVLGEQ-SPDMILPIHVMKNLRAISFDPLERLVYWVDGR-QNIRRSRDDGTQASTVMTPNSDHP--KQPHDLSLDPYSRTVYWTCETTNTINIHRMDGHIIGEVLKDDVDKPRAIVVNAEKGYMYFTTVQERSAKIEGASLDGTERESLFTTSLIRPVALALDNKLGKLFWVDADLKRIESSDLSGANRIVLQDSNILQPVGLTVLGDHLYWIDKQQQMIERVDKLTGEKRTRIQGRLQYLTGIHAVQYMETDEFATHPCSRDNGGCSHICIAKGDGTPR----CSCPMHLVLLQNLLSCGEPPTCSSEQFTCAT-------GEIDCIPMAWRCDGIAECADNSDEMNCPICSKLQFQCDKGQCVDIQVRCNGEPDCADGSDEQDCETICLSNQFRCGN-SQCILKKQQCDSFPDCTDESDE---RFCDFP-PPPNDLPRHTSTIGPVIGIILSVFVMGGMCFVCQRVVCRHYKGPNGGFPHEYISGTPHVPLNFIAPTNSQHG--KGISCGKSMMSSVSLMGSSSSGAPLYDRNHVTGASSSSSSSTKGAFYPQMLNPPPSPATDRSLYNAEVFYSSNSPSTTRSYRPYLMRGVAPPTTPCSTDVCDSDYTTSRWKSNK----------------YYMDLNSDSDPYPPPPTPRSQYMS-----AEESCPPSPSTERS-YFHLCPPPPSPCTDSS----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z9D7-1", "uniprot_id": "A1Z9D7_DROME", "id": "A1Z9D7-1", "name": "Low-density lipoprotein receptor-related protein", "aln": "MALEPYTKSAEIEPQLCQVIDNNEDVTTKATKCTKSNSGVGWRQMLIGFLLICFGISNSWQYKNVHMPSSSSLIASPPASAFVNTPATLLFTTRHDIQVANITRPTGGPQIDVIVRDLAEAMAIDFYYAKNLVCWTDSGREIIECAQTNSSALQPLLR--APKQTVISTGLDKPEGLAMDWYTDKIYWTDGEKNRIEVATLDGRYQKVLFWTDLDQPRAVAVVPARKLLIWTDWGEYPKIERASMDGDPLSRMTLVKEHVFWPNGLAVDLKNELIYWTDGKHHFIDVMRLDGSSRRTIVN-NLKYPFSLTFYDDRLYWTDWQRGSLNALDLQTR-ELKELIDTPKAPNSVRAWDPSLQPYEDNPCAHNNGNCSHLCLLATNSQGFSCACPTGVKLIS-ANTCANGSQEMMFIVQRTQISKISLDSPDYTIFPLPLGKVKYAIAIDYDPVEEHIYWSDVETYTIKRAHADGTGVTDFVTSEVRHPDGLALDWLARNLYWTDTVTDRIEVCRLDGTARKVLIYEHLEEPRAIAVAPSLGWMFWSDWNERKPKVERASLDGSERVVLVSENLGWPNGIALDIEAKAIYWCDGKTDKIEVANMDGSGRRVVISDNLKHLFGLSILDDYLYWTDWQRRSIDRAHKITGNNRIVVVDQYPDLMGLKVTRLREVRGQNACAVRNGGCSHLCLNRPRDYVCRCAIDYELANDKRTCVVPAAFLLFSRQEHIGRISIEYNEGNHNDERIPFKDVRDAHALDVSVAERRIYWTDQKSKCIFRAFLNGSYVQRIVDSGLIGPDGIAVDWLANNIYWSDAEARRIEVARLDGSSRRVLLWKGVEEPRSLVLEPRRGYMYWTESP-TDSIRRAAMDGSDLQTIVAGANHAAGLTFDQETRRLYWATQSRPAKIESADWDGKKRQILVGSDMDEPYAVSLYQDYVYWSDWNTGDIERVHKTTGQNRSLVHSGMTYITSLLVFNDKRQTGVNPCKVNNGGCSHLCLAQPGRRGMTCACPTHYQLAKDGVSCIPPRNYIIFSQRNCFGRLLPNTTDCPNIPLPVSG-KNIRAVDYDPITHHIYWIEGRSHSIKRSLANGTKVSLLANSG-------QPFDLAIDIIGRLLFWTCSQSNSINVTSFLGESVGVIDTGDSEKPRNIAVHAMKRLLFWTDVGSHQAIIR-ARVDGNER-VELAYKLEGVTALALDQQSDMIYYAHG--KRIDAIDINGKNKKTLVSMHISQVINIAALGGFVYWLD-DKTGVERIT-VNGERRSAELQRLPQITDIRAVWTPDPKVLRNHTCMHSRTKCSHICIASGEGIARTRDVCSCPKHLMLLEDKENCGAFPACGPDHFTCAAPVSGISDVNKDCIPASWRCDGQKDCPDKSDEVGCPTCRADQFSCQSGECIDKSLVCDGTTNCANGHDEADCCKR--PGEFQCPINKLCISAALLCDGWENCADGADESSDICLQRRMAPATDKRAFMILIGATMITIFSIVYL--------LQFCRTRIGKSRTEPKDDQATDPLSPSTLSK---SQRVSKIASVADAVRMSTLNSRNSMNS----YDRNHITGASSSTTNGSSMVAYP--INPPPSPATR----------------SRRPYRHYKIINQPPPPTPCSTDICDESDSNYTSKSNSNNSNGGATKHSSSSAAACLQYGYDSEPYPPPPTPRSHYHSDVRIVPESSCPPSPSSRSSTYFSPLPPPPSPVQSPSRGFT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * : . .** ***:.*:*:::.: : ::. .* :* *:** :::. : *** ..* *: : * : . *.:: :** .*:*** ** .*:****.*.******.*:* :***** *******:*: *:: : ****** *:****.***. .* :*...::*****::**.:: :**:*.* **. .***: *. :*: .*.:**:**: .: ******* *::* : : : :*::. :* .::. . . ** .. * . **.*******:. ::*******:* . ..** *:::::::.:**:: :**** **:* : * :..:::********:* ::**:* * :*:** **:.. ::..*:..***:*:**:********* ****** **:**:*::*: *.*:*****.: * * *:*:**.* **:* *.*** :* **:. .******:*:* :** *.******* *:**: * .::.*:* *:**:::*.:::**********:*.* ... * *:::* *******...: :. * * ** ********: *: * *.:. ** .* :**::* ***:*: : * **: * ** **:..*::* ***..* :.:***** . * * ***:*** *: ::: ** *:*:****:..*:**:*: :.*********. *:**: :.:::****.*:* .**:**** * ** ***:: *:* ..:* .**:* :****: . ***:: * :* ::..*: *:.:: * **:**:*** .***..* :* **::::. : :: .:***:..** * * * .** *.:**** *. * * *.:** * .. .* .* .:::***: .:.*:: . .*:: **: :*::*:.:**: : :**::** :.*:*: :**: : . . **.**::* .* ::***. :*:**: : *. :* : .* ::** *.*:* : :::* : .: * *. * :**.** :: * .**.:*: . :::... ***:: *:.* *: .* . :* * :.:: ** .:**:* :: :**: .*::*: *: :*.*:** . . : *.* :.. *******.*:* .* **** **:**:: .** *:*..::*:*:: : **** :***** :* *:*** .** * ** * *:*:* : *:* .:* : ** :* ..:*:* *: **.: :* * :** : .*. * . **..: *:*:. : .*: * . *:: . * * .: **: . .. **::. .. .. *****:******::..:. . ** :******** : *.** * : . .**.******:**.. : *:.. :: . **:********:*:* * .*.****** :. * * ****** ..* ", "identical_positions": 628, "similar_positions": 513, "identity": "36.24%" }, { "cls_id": "homologset.agr.RGD:1309330", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5ND28-1", "uniprot_id": "SREC_MOUSE", "id": "Q5ND28-1", "name": "Scavenger receptor class F member 1", "aln": "MLAAMGLELVFSLLLLWTQGTQGSTLDPAGQHVCKGSSP-SELQCCPGWRQKDQECTIPICEGPDACRKEEVCVKPGLCRCKPGFFGAQCSSRCPGQYWGHDCRETCPCHPRGQCEPATGDCQCQPNYWGRLCEFPCTCGPHGQCDPKTGLCHCDPGWWSPTCRRPCQCN-PASRCDQATGTCVCPPGWWGRRCSFSCNCHTSPCMQDSGRCVCLPGWWGPECSRKCQCVRGQCSVTSGHCSCPPGFHGIRCELPCNPGHYGAQCKESCGHCELNATCSPVTGNCESCKPGWNGTQCKQPCPAGTFGERCTGQCPRCRLGEPCQAETGHCQHCDPGWLGHRCENPCPLGTFGKGCSSTCPACAQGTCDAVTGECVCSAGYWGTSCNSSCPAGFHGNNCSMPCQCPEGLCHPVSGTCQLGRHGKN-ALIVGILVPLLLLLMGIVCCAYCCSGTRLDPKDRPERNGAAFFRMKQQVWGALTNLGSALPCGSLSNYKLPWVTVSHHDPEVPFNHSFIEPPSAGWASDDSFSSDPDSGEEDEAHAYFVPPREEMVPMAQEESPEASLPGGSFPPPEDASTPFPIPRTSSLARAKRPSVSFAEGTKFAPQNGRSSGDLSSPIRKPKRLSRGAQPRPEGQEAEESTGPEQVNTEEDAPTATSSGDPATSHGQLPPGSQMVAECAETTDGGIQESSGSVATIYMLAGTPQKPEGPVWSVFRRLGNYQKDQMDPKVKSAIPKPLRRSLGRNQAS-----------AGSAPGAVLSQAMESTAVRPEETPRGLGDGIESSGTVQEPDAGGSSLEQDSQKQAEEKEQEEPLYENVVPMSVPPQH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZRK9-1", "uniprot_id": "A0A8I5ZRK9_RAT", "id": "A0A8I5ZRK9-1", "name": "", "aln": "MLTAMGLGLVFSLLLFWTREIQGSTLDPAGQHVCIGSSP-SELQCCSGWRQKDQECTIPICEGPDACKKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRETCPCHPRGQCEPATGVCQCQPNYWGKLCEFPCTCGPHGKCDPKTGLCHCDPGWWSPTCRRPCQCN-PLARCDQVTGACICPTGWWGHRCSFSCNCHTSPCLQDSGRCTCLQGWWGPECSRRCQCVRGQCSVTSGHCSCPPGFQGALCELPCKPGRYGAQCKESCGHCEPNATCSPVTGNCESCKPGWNGTQCKQPCPPGTFGERCTGKCPRCRLEEPCQVETGHCQRCDPGWLGHRCEKPCPLGTFGKGCSSTCPACVQGTCNAVTGECVCSAGYWGTSCNSSCPSGFHGNNCSMPCQCPEGLCHPESGACQLGPHGKN-ALIVGILVPLLLLLMGIICCVYCCSASRLDPKDRPERNGAAFFRMKQQVWGALTSLGSALPCGSLSNYKLPWVTVSHHDPEVPFNHSFIEPPSAGWASDDSFSSDPDSGEEDEAHAYFMPPREETVPMTQEESPAASLPGGPFPPPEDASTPFPIPRTSSLARAKRPSVSFAEGTKFAPQNGRSSGDLSSPIRKPKRLSRGAQPRPEGQEAEESTGPEQENPEEDVPTATSSGDAATSHGQLPPGSRTVTECVETTDGGIQESSGSVATIYMLAGTPQKPEGPVWSVFRRLGNYQKDQAAPKVKSAIPKPLRRSLGRNQASSGLSQ-----SSGSAPGAVLSGAMESTAVKPEEASRGLGDGIESLGTVQEPVVGSSSPEQGSQKQAEEQEQEEPLYENVVPM---LQH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14162-1", "uniprot_id": "SREC_HUMAN", "id": "Q14162-1", "name": "Scavenger receptor class F member 1", "aln": "----MGLGLLLPLLLLWTRGTQGSELDPKGQHVCVASSPSAELQCCAGWRQKDQECTIPICEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRGRCSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCECPEGLCHPVSGSCQPGSGSRDTALIAGSLVPLLLLFLGLACCACCCWAPRSDLKDRPARDGATVSRMKLQVWGTLTSLGSTLPCRSLSSHKLPWVTVSHHDPEVPFNHSFIEPPSAGWATDDSFSSDPESGEADEVPAYCVPPQEGMVPVAQAGSSEASLAAGAFPPPEDASTPFAIPRTSSLARAKRPSVSFAEGTKFAPQSRRSSGELSSPLRKPKRLSRGAQSGPEGREAEESTGPEEAEAPESFPAAASPGDSATGHRRPPLGGRTVAEHVEAIEGSVQESSGPVTTIYMLAGKPRGSEGPVRSVFRHFGSFQKGQAEAKVKRAIPKPPRQALNRKKGSPGLASGSVGQSPNSAPKAGLPGATGPMAVRPEEAVRGLGAGTESSRRAQEPVSGCGSPEQDPQKQAEEERQEEPEYENVVPISRPPEP", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *** *::.***:**: *** *** ***** .*** :*****.********************:*:******************:*********** ****:*****:******** ****.: ** *****:*****:*** **:***:*****.********* . :**:*.**:*:* .****:**** **** *** ******.* *******.::*:****:**.:**.*:*****:* ***** .* :*.** .***:*: * .*** **.****:********:*** .***** * :**:** *.*: :*****:******* ***.*** ****:.*.****:*.**:*::***:*********.***:***:********:**:******** **:** * .:: ***.* *******::*: **. ** ..* * **** *:**:. *** ****:**.***:*** ***.:*****************************:********:*** **. ** :**:* **::* *. ***..*.***********.**************************. ****:****:***********. ***:*********: :. *. *:*:*.**.**.* : * *.: *:* .*: :*.:*****.*:*******.*: .**** ****::*.:**.* .*** ***** *::*.*::.* ..*** * *. * . **:***: **** * ** .*** * .* **..******:.**** ******: : ", "identical_positions": 563, "similar_positions": 156, "identity": "67.51%" }, { "cls_id": "homologset.agr.RGD:1309332", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZZ42-1", "uniprot_id": "D3ZZ42_RAT", "id": "D3ZZ42-1", "name": "Matrix metalloproteinase-21", "aln": "MLAVSDLRLTMLLCWLVTPQPAQPERLFHSRDRSDLEPSPLSRAKPIADLHAAQNFLLKYGWSEV-----SSPKESAG-------------------VPVGFTLAQAVRRFQKANRLPASGKLDSPTLAAMNKPRCGVPDTRLPLQDAL---------PTPPALPTPLGLQPRARQKRFLQMLLPKPGGKQEGRSDTGASRVFSKKTLTWRLVGDAYSSQLSGDEQRYIFRLAFRMWSEVTPLDFREDLTAPGTMVDIKLGFGRGRHLGCPRVFDGSGQEFAHAWHLGEIHFDDDEHFTPLSSDTGISLLKVAVHEIGHVLGLPHTYRVGSIMQPNYIPQEPAFELDWSDRKAIQRLYGSCEGSFDIVFDWIRKERNQYGEVRVRFNTYFFRNSWYWLYENRNNRTRYGDPLQILTGWRGIPMQRIDAFVHVWSWGRDERYFFKGNQYWRYDSENDQAHTQDEQGRSYPKLISEGFPGIPSPLDTAFYERRQQLIYFFKESLVYAFDVNRNQALSSYPKKMSQVFPAIMPQNHPFRNLDSAYYSYAHNAIFFFKGNSFWKVVSDKDKQQDSRLPLNGLFPKQSVSGKWFDVCDVHTSTLNM----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K3F2-1", "uniprot_id": "MMP21_MOUSE", "id": "Q8K3F2-1", "name": "Matrix metalloproteinase-21", "aln": "MLAASVLRLTLPLCWLVAPQPTQPERLFHSRDRSDLEPSPLSQAKPIADLHDAQSFLLKYGWSEI-----PSPKESAG-------------------VPVGFTLAQAVRRFQKANRLPASGELDSPTLAAMNKPRCGVPDTRLPPRAAL---------PTPPALLTSLGLRPRARQKRFLQMLFPKPDGQQEDASDTGASRAFSKKTLTWRLVGDAYSSQLSGDEQRYIFRLAFRMWSEVTPLDFREDRTAPGTMVDIKLGFGRGRHLGCPRVFDGSGQEFAHAWRLGEIHFDDDEHFTPLSSDTGISLLKVAVHEIGHVLGLPHTYRVGSIMQPNYIPQEPAFELDWADRKAIQRLYGSCKGSFDTVFDWIRKERNQYGEVRVRFNTYFFRNSWYWLYENRNNRTRYGDPLQILTGWRGIPTQSIDAYVHVWSWGKDERYFFKGSQYWRYDSENDQAHTEDEQGRSYPKLISEGFPGIPSPLDTAFYDRRQQLIYFFKESLVFAFDVNRNQVLNSYPKKMSQVFPAIMPQNHPFRNLDSAYYSYAHNSIFFFKGNSYWKVVSDKDKQQNTRLPLNGLFPKKPVSEKWFDVCDVHTSTLNM----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N119-1", "uniprot_id": "MMP21_HUMAN", "id": "Q8N119-1", "name": "Matrix metalloproteinase-21", "aln": "MLAASIFRPTLLLCWLAAPWPTQPESLFHSRDRSDLEPSPLRQAKPIADLHAAQRFLSRYGWSGVWAAWGPSPEGPPE-------------------TPKGAALAEAVRRFQRANALPASGELDAATLAAMNRPRCGVPDMRPPPPSAP---------PSPPGPPP----RARSRRSPRAPLSLSRRGWQPRGYPDGGAAQAFSKRTLSWRLLGEALSSQLSVADQRRIVALAFRMWSEVTPLDFREDLAAPGAAVDIKLGFGRGRHLGCPRAFDGSGQEFAHAWRLGDIHFDDDEHFTPPTSDTGISLLKVAVHEIGHVLGLPHTYRTGSIMQPNYIPQEPAFELDWSDRKAIQKLYGSCEGSFDTAFDWIRKERNQYGEVMVRFSTYFFRNSWYWLYENRNNRTRYGDPIQILTGWPGIPTHNIDAFVHIWTWKRDERYFFQGNQYWRYDSDKDQALTEDEQGKSYPKLISEGFPGIPSPLDTAFYDRRQKLIYFFKESLVFAFDVNRNRVLNSYPKRITEVFPAVIPQNHPFRNIDSAYYSYAYNSIFFFKGNAYWKVVNDKDKQQNSWLPANGLFPKKFISEKWFDVCDVHISTLNM----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0N9E2K8-1", "uniprot_id": "MMP21_DANRE", "id": "A0A0N9E2K8-1", "name": "Matrix metallopeptidase-21", "aln": "MLTVIRRIFIIQTFIFIT-----AEKIFHSRDHSDVLNN-IHQAELITDTDTAQRFLSKYGFIKAAGSEESQLSESSGDLDFSLSLDLHEGGTTSGSSSSDLQFVSALRDFQRLSDLPVTGVFDDATKAAMNKPRCGVMDDDQELKDVTGSNSTRNHIRTSTNTSHNHEHQAPVRKKRHLSALLKNTSLQKRDVSKWTGHMAFSKSVLKWRLIGEGYSSQLSIQEQKYIFRLAFRMWSEISPLQFIEDLHSPLENIDIRLGFGTGRHLGCSQRFDGAGREFAHAWFLGDIHFDDDEHFTVPNTGSGISLLKVAVHEIGHVLGLPHIYRPGSIMQPSYLPQDAGFEIDWMDRKSIQRLYGVCTGRFSTVFDWIRKEQTPYGEVVVRFNTYFMRDGLYWLYENRNNRTRYGDPVAVQVGWHGLPSGGVDAYVHVWNRKTDAVYFFKGMQYWRYDSENDHVFSHAPDGRLYPRLISEDFPGVSGPLDTAYYDRRDAHIYFFKGSQVFRFDVRMRRLASSSPQEMTEVFPAIVSGDHPVRSLDAAYFSYTHNTVFLLKGSLFWRVLSGKERRRRAFLPMNGLLAHRRVHEQWFDICDVHSSSLRTTRRR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:. : : : .* :*****:**: . : :*: *:* . ** ** :**: .. . .. . . :..*:* **: . **.:* :* .* ****:***** * . :.. :. *:. : . . : .. .. . .*** .*.***:*:. ***** :*: *. ********::**:* ** :* :**:**** ******.: ***:*:****** **:********** .:.:******************** ** ******.*:**:..**:** ***:**:*** * * *. .*******:. **** ***.***:*:. ****************: : .** *:* :**:**:*. * ***:* *******::*:. :. :*: **:****.***:..*****:*:**: ***** * *: ***. .: .* *:.:::****::. :**.*.:*:**:**::*::*::**. :*:*:..*:::: : ** ***:.:: : :***:**** *:*. ", "identical_positions": 267, "similar_positions": 162, "identity": "44.13%" }, { "cls_id": "homologset.agr.RGD:1309333", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L854-1", "uniprot_id": "A0ABK0L854_RAT", "id": "A0ABK0L854-1", "name": "Protein maelstrom homolog", "aln": "MPNRRASRNAYYFFVQEKIPELRRRGLPVARVADAIPYCSADWALLREDEKEKYSEMAREWRAAQGKDSGPSEKQGLVMAHWLKARATLPEDPVSSQCTYMKLVSTPLRRPGMLVPKPSVSPPDMSNLSIKSDQALLGGVFYFLNIFSHGELPPHCEQRFLPCEIGCVKYSLQEGIMADFHSFINPGEIPRGFRFHCQAASDSSHKIPISNFEFG-HDQATVLQNLYKFIHPNPGN--WPPIYCKSDDRARVNWCLKRMERASEIR---QDLELLTVEDLVVGIYQQKFLKEPS------KTWVRSLLDVAMWDYSSNTRCKWHEEND-ILFCALAVCKKIAYCISNSLATLFGIQLT-GAHVPLQDYEASNSVTPKMVVLDAGRYQKLRVESPGFCHFNSYNQEQRSNSSTGYYPSGVKISGSNSSVRGRGITRLLESISNSSNNIHRFSNCEASLS-----------PYMPQKDGYKPFSSFS-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BVN9-1", "uniprot_id": "MAEL_MOUSE", "id": "Q8BVN9-1", "name": "Protein maelstrom homolog", "aln": "MPNRRASRNAYYFFVQEKIPELRRRGLPVARVADAIPYCSADWALLREDEKEKYSEMAREWRAAQGKDSGPSEKQ--------------------------KLVSTPLRRPGMLVPKPSISPPDMSNLSIKSDQALLGGIFYFLNIFSHGELPPHCEQRFLPCEIGCVKYSLQEGIMADFHSFIHPGEIPRGFRFHCQAASDSSHKIPISNFEFG-HDQATVLQNLYKFIHPNPGN--WPPIYCKSDDRARVNWCLKRMERASEIR---QDLELLTVEDLVVGIYQQKFLKEPS------KTWVRSLLDVAMWDYSSNTRCKWHEEND-ILFCALAVCKKIAYCISNSLATLFGIQLT-GAHVPLQDYEASNSVTPKMVVLDAGRYQKLRVESPGFCHFNSYNQEQRSNTSTGYYPSGVKISGPHSSVRGRGITRLLESISNSSNNIHRFSSCETSLS-----------PYTPQKDGYKPFSSFS-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96JY0-1", "uniprot_id": "MAEL_HUMAN", "id": "Q96JY0-1", "name": "Protein maelstrom homolog", "aln": "MPNRKASRNAYYFFVQEKIPELRRRGLPVARVADAIPYCSSDWALLREEEKEKYAEMAREWRAAQGKDPGPSEKQ--------------------------KPVFTPLRRPGMLVPKQNVSPPDMSALSLKGDQALLGGIFYFLNIFSHGELPPHCEQRFLPCEIGCVKYSLQEGIMADFHSFINPGEIPRGFRFHCQAASDSSHKIPISNFERG-HNQATVLQNLYRFIHPNPGN--WPPIYCKSDDRTRVNWCLKHMAKASEIR---QDLQLLTVEDLVVGIYQQKFLKEPS------KTWIRSLLDVAMWDYSSNTRCKWHEEND-ILFCALAVCKKIAYCISNSLATLFGIQLT-EAHVPLQDYEASNSVTPKMVVLDAGRYQKLRVGSSGFSHFNSSNEEQRSNTPIGDYPSRAKISGQNSSVRGRGITRLLESISNSSSNIHKFSNCDTSLS-----------PYMSQKDGYKSFSSLS-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VNS0-1", "uniprot_id": "MAEL_DROME", "id": "Q9VNS0-1", "name": "Protein maelstrom", "aln": "MAPKKHSG--FMMFVNEWR--NRNAEGRRMTLAQAVSHCGTIWEKMNTQQRGPYNSGGKDANVAQRAKRESSNGHG-------------------------QVDKAQREATESLMDMKRTIERLVLNAKMSHDLENAKFVFVAFNYFTK----ALTTDVYVPAEFAACEYSLKEGIRSIYSTMIDPGQIIFGQGSDALLHSSTTHDLPLPPNALGEKNMTKLYRNIVDYLSKCQGKGKTLVVFTPAENITMVKSCFRYLECDDDFRDGGEKIQVFDIQYLLFILKKEVMNVADLNDEKINKFATDAFFKKDFFEFTAGIACQYHEDNDRTKYCTQSMVTRWAYTFTDFMCGDLAITVQPGKHIPAQTKPNYLIISSYASSLDHESSFDSFYSLPGSGVKKESQPEACSLSSSRLSVASSSYKPIDHTSFAANLNEVSEFPSLGMRNSSKHHGIAASAQREWNARNLPTHSRLIRKVSDNDFSVNGADGKLKK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. :: * : :**:* *. :*:*:.:*.: * :. ::: * . .:: ..** . .*: : : : . . *: : .:. * :* :* *:: . : ::*.*:.. :***:*** : : ::*.**:* * .. *.::*.:*:. * :: :.: :*: :: *: :: ::: : *: *:: : .::* :.:::: :: *:. : :: : * :::. ::::::. *::**:** :*: :: .: ** ::: :. :.* : *:* * ::. ** . .* :. : * * :. : . . . : . .:..: * * . * :. . :* . . :* . : ** . ", "identical_positions": 67, "similar_positions": 165, "identity": "13.62%" }, { "cls_id": "homologset.agr.RGD:1309334", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5Y5T2-1", "uniprot_id": "ZDH18_MOUSE", "id": "Q5Y5T2-1", "name": "Palmitoyltransferase ZDHHC18", "aln": "MKDCEYQQISPGAAPPPASPGARRPGPAAPPAPSPGPAP----GAPRWS------GSGSGSGSLGRRPRRKWEVFP--GRNRFYCGGRLMLAGHGGVFALTLLLILST-TILFFVFDCPYLARTLT--LAIPIIAAILFFFVMSCLLQTSFTDPGILPRATICEAAALEKQIDN---TGSSTYRPPPRTREVMINGQTVKLKYCFTCKMFRPPRTSHCSVCDNCVERFDHHCPWVGNCVGRRNYRFFYAFILSLSFLTAFIFACVVTHLTLLSQGSN-FLSALKKTPASVLELVICFFSIWSILGLSGFHTYLVASNLTTNEDIKGSWSS----KRGGEASVNPYSHKSIITNCCAVLCGPLPPSLIDRRGFVQS---------DTALPSPIRSDDPACGAKPDASMVGG----------------------------HP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q2TGJ1-1", "uniprot_id": "ZDH18_RAT", "id": "Q2TGJ1-1", "name": "Palmitoyltransferase ZDHHC18", "aln": "MKDCEYQQISPGAAPPPASPGVHRPGPAAPPGPSPGPAP----GAPRWSVSGSGSGSGSGSGSLGRRPRRKWEVFP--GRNRFYCGGRLMLAGHGGVFALTLLLILST-TILFFIFDCPYLARTLT--LAIPIIAAILFFFVMSCLLQTSFTDPGILPRATICEAAALEKQIDN---TGSSTYRPPPRTREVMINGQMVKLKYCFTCKMFRPPRTSHCSVCDNCVERFDHHCPWVGNCVGRRNYRFFYAFILSLSFLTAFIFACVVTHLTLLSQGSN-FLSALNKTPAGVLELVICFFSIWSILGLSGFHTYLVASNLTTNEDIKGSWSS----KRGGEASVNPYSHKSIITNCCAVLCGPLPPSLIDRRGFVQS---------DTVLPSPIRSDEPACGAKPDASMVGG----------------------------HP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NUE0-1", "uniprot_id": "ZDH18_HUMAN", "id": "Q9NUE0-1", "name": "Palmitoyltransferase ZDHHC18", "aln": "MKDCEYQQISPGAAPLPASPGARRPGPAASPTPGPGPAPPAAPAPPRWS--SSGSGSGSGSGSLGRRPRRKWEVFP--GRNRFYCGGRLMLAGHGGVFALTLLLILTT-TGLFFVFDCPYLARKLT--LAIPIIAAILFFFVMSCLLQTSFTDPGILPRATVCEAAALEKQIDN---TGSSTYRPPPRTREVLINGQMVKLKYCFTCKMFRPPRTSHCSVCDNCVERFDHHCPWVGNCVGRRNYRFFYAFILSLSFLTAFIFACVVTHLTLRAQGSN-FLSTLKETPASVLELVICFFSIWSILGLSGFHTYLVASNLTTNEDIKGSWSS----KRGGEASVNPYSHKSIITNCCAVLCGPLPPSLIDRRGFVQS---------DTVLPSPIRSDEPACRAKPDASMVGG----------------------------HP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZVN4-1", "uniprot_id": "ZD18B_DANRE", "id": "Q7ZVN4-1", "name": "Palmitoyltransferase ZDHHC18-B", "aln": "MKNREYQQIDPQALATPTP--------TPPPRSLPEHKP--------------------------RRARRKWEVFP--GKNRFYCDGRIIVARQSGVLPLTLGLILLT-SGLFFIFDCPFLVKHLT--SCIPAIGGVLFVFVIISLLQTSFTDPGILPRATPEEAADIEKQIDNP-TGSSSSYRPPPRTKEVVINQQVVKLKYCFTCKIFRPPRTSHCSLCDNCVERFDHHCPWVGNCVGKRNYRFFYTFIVSLSFLTAFIFGCVTTHLALRSQGGNGLVNALQSSPASALELVVCFFSVWSILGLSGFHTYLVAANLTTNEDIKGSWSG----KSGNEDVGNPYSYNSMIKNCCSVLCGPMPPSLIDRRGFVPSD--------DSVQTSPVEIELPA--AKNDINMVGR-----------------------AVTSGRP----------------------------------------------------PPPPPP-----------PLVVTLQQPAIS---MQNHSTA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E7FH11-1", "uniprot_id": "ZD18A_DANRE", "id": "E7FH11-1", "name": "Palmitoyltransferase ZDHHC18-A", "aln": "MKNCEYQQIDPRALRTPSSR-------TSSTLPCGRKGS--------------------------QRLRRKWEVFP--GKNRFYCDGRIMLARQCGVLPLTIGLIFIT-SVLFFTFDCPFLVDHLT--VFIPVIGGVLFIFVVISLLQTSFTDPGILPRALPDEAADIEKQIDN---SGSSTYRPPPRTKEILINDQVVKLKYCFTCKMFRPPRTSHCSLCDNCVERFDHHCPWVGNCVGKRNYRFFYAFIVSLSFLTSFIFGCVITHLTLRSQGGNGFIQAIQDSPASVVELVICFFSIWSILGLSGFHTYLVASNLTTNEDIKGSWSS----KRG-EESGNPYTYNNIFTNCCVVLCGPMPPSLIDRRGFVPPE--------DAPQTVTSDAELPAFMAKNDTNMCAQGTKELLE------SMANSTVIQSTCAPGKPKTAPVTQE---------------------------------SLLNTVSITVSPPSKPPSNGCSGRQARRPIDVPCSQRGLKRAALHTHKPMLRLPSPLYSLSDSPLILSDAPDMGFIPLN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A2VEY9-1", "uniprot_id": "APP_DROME", "id": "A2VEY9-1", "name": "Palmitoyltransferase app", "aln": "-----MNLLCCCCCSNMAP---------------------------------------------NQRVTRKWELFA--GRNKFYCDGLLMSAPHTGVFYLTCILITGT-SALFFAFDCPFLADSIN--PAIPIVGAVLYFFTMSSLLRTTFTDPGVIPRASNDEAAYIEKQIEVPNSLNSPTYRPPPRTKEVLVKGQTVKLKYCFTCKIFRPPRASHCSLCDNCVDRFDHHCPWVGNCVGKRNYRFFYLFLVSLAFLAVFIFSCSVTHLVLLMKKEHEVFNVIKAAPFTVIVVFICFFSIWSVIGLAGFHTYLTTSDQTTNEDLKGSFSS----KGG-PRTQNPYSRGNICLNCCHILCGPMTPSLIDRRGIATDEFIQQMQHQSSPRHALSDVLSASHMVTTSQPMMGGLGGGGIGGAGGGISIGGAELKPRFYDESNPSSSTLEGNGGAINGHGNGHGNGFDHPPPSYDLVQNGNSNSLAQLVDNEIPLVQMDIPAYTHQTATQARQYRHRHHKQRQICNGGTVSYENQLANASSEDELDDPDVVVVGSPEVVAAVAAIASNKAREMRNRSGSYSNLFDADFEAALVNSSLADNHVRGEGASSSGKPSAGAALLAAAISGKTENMYSNVLPVDNDTDPADSTLHVYSNIIDERKQQEQANNVLSSTLLCDDLDLDDPVSASCHVKRKSLGDGAEQVKSAERLRMLHDNTMIDTALDLDSLDGSSMGNNSQSCLVKSGKPNATSVTTNVAIV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06551-1", "uniprot_id": "ERFB_YEAST", "id": "Q06551-1", "name": "Palmitoyltransferase ERF2", "aln": "MALVSRRSTRSESTSITKEEHTGEGSLTKLFFRWLVTLE----------------------GDQDINDGKGYISLPNVSNYIFFLGGRFRTVKGAKPLWLGVLLAIVCPMVLFSIFEAHKLWHTQNGYKVLVIFFYYFWVITLASFIRTATSDPGVLPRNIHLSQLRNNYQIPQ-------EYYNLITLPTHSSISKDITIKYCPSCRIWRPPRSSHCSTCNVCVMVHDHHCIWVNNCIGKRNYRFFLIFLLGAILSSVILLTNCAIHIARESGGPR-------DCPVAILLLCYAGLTLWYPAILFTYHIFMAGNQQTTREFLKGIGSKKNPVFHRVVKEENIYNKGSFLKNMGHLMLEPRGPSFVSARKPHEAG------------DWRFMDLSPAHSFEKIQKI----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . : : :. .. *: .* : . : * * ** *:. * . : . ::.:.: .:::*: :***::** . : ** * : :.:*** :*:::****:**** *: ** .**** **.**:*:****** *::. : : ::: *:. . * : : . :::* * :* ::. : **.* :** * * *. .: * :: * **::. * .: : ", "identical_positions": 66, "similar_positions": 84, "identity": "8.76%" }, { "cls_id": "homologset.agr.RGD:1309335", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AL43-1", "uniprot_id": "A0A8I6AL43_RAT", "id": "A0A8I6AL43-1", "name": "Arginyl-tRNA--protein transferase 1", "aln": "MASWSAPSPSLVEYFEGQTSFQCGYCKSNFG--------------------------SRSHGMWAHSMTVQDYQDLIDRGWRRSGKYVYKPVMNQTCCPQYTIRCHPLQFQPSKSHKKVLKKMLKFLAKGEISKGNCEDEPMDSTMEDAVDGDFALMNKLDIKCDLKTLSSDLKVSIESEEKEKEKSLKKEGSKDLIHPQ-AIEEKLGSGEPSHSIKVHVGPKPGKGADLSKPPCRKAKEMRKERKRLKLMQQSSAGAFEGFQAQGQPVSLLP-KAKSNQPKSLEDLIFESLPEDASHKLEVRVVRSSPPSPQFKATFQESYQVYKRYQMIIHKDPPDKPTVSQVRLVPASFEDPEFKSSFNQSLSLYTKYQVAIHQDEPDICDKSEFTRFLCNSPLEAEHPANGPECGYGSFHQQYWLD--GKIIAVGVIDILPYCVSSVYLYYDPDYSFLSLGVYSALREIAFTRQLHEKTSQLSYYYMGFYIHSCPKMRYKGQYRPSDLLCPETYVWVPIEQCLPS-LDNSKYCRFNQDPQAEDEGR--SKELDRLRVFHR-RSAMPYGVYKNHQEDPSEEAVVLEYANLVG-QKCSETMLLFRH--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z2A5-1", "uniprot_id": "ATE1_MOUSE", "id": "Q9Z2A5-1", "name": "Arginyl-tRNA--protein transferase 1", "aln": "MASWSAPSPSLVEYFEGQTSFQCGYCKNKLG--------------------------SRSYGMWAHSMTVQDYQDLIDRGWRRSGKYVYKPVMDQTCCPQYTIRCHPLQFQPSKSHKKVLKKMLKFLAKGEISKGNCEDEPMDSTVEDAVDGDFALINKLDIKCDLKTLS-DLKGSIESEEKEKEKSIKKEGSKEFIHPQ-SIEEKLGSGEPSHPIKVHIGPKPGKGADLSKPPCRKAREMRKERQRLKRMQQASAAASE---AQGQPVCLLP-KAKSNQPKSLEDLIFQSLPENASHKLEVRVVRSSPPSPQFRATFQESYQVYKRYQMVVHKDPPDKPTVS-------------------------------------------QFTRFLCSSPLEAEHPADGPECGYGSFHQQYWLD--GKIIAVGVLDILPYCVSSVYLYYDPDYSFLSLGVYSALREIAFTRQLHEKTSQLSYYYMGFYIHSCPKMRYKGQYRPSDLLCPETYVWVPIEQCLPS-LDNSKYCRFNQDPEAEDEGR--SKELDRLRVFHR-RSAMPYGVYKNHQEDPSEEAGVLEYANLVG-QKCSERMLLFRH--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95260-1", "uniprot_id": "ATE1_HUMAN", "id": "O95260-1", "name": "Arginyl-tRNA--protein transferase 1", "aln": "MAFWAGGSPSVVDYFPSEDFYRCGYCKNESG--------------------------SRSNGMWAHSMTVQDYQDLIDRGWRRSGKYVYKPVMNQTCCPQYTIRCRPLQFQPSKSHKKVLKKMLKFLAKGEVPKGSCEDEPMDSTMDDAVAGDFALINKLDIQCDLKTLSDDIKESLESEGKNS----KKEEPQELLQSQDFVGEKLGSGEPSHSVKVHTVPKPGKGADLSKPPCRKAKEIRKERKRLKLMQQNPAGELEGFQAQGHPPSLFPPKAKSNQPKSLEDLIFESLPENASHKLEVRVVRSSPPSSQFKATLLESYQVYKRYQMVIHKNPPDTPTES-------------------------------------------QFTRFLCSSPLEAETPPNGPDCGYGSFHQQYWLD--GKIIAVGVIDILPNCVSSVYLYYDPDYSFLSLGVYSALREIAFTRQLHEKTSQLSYYYMGFYIHSCPKMKYKGQYRPSDLLCPETYVWVPIEQCLPS-LENSKYCRFNQDPEAVDEDR--STEPDRLQVFHK-RAIMPYGVYKKQQKDPSEEAAVLQYASLVG-QKCSERMLLFRN--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O96539-1", "uniprot_id": "ATE1_DROME", "id": "O96539-1", "name": "Arginyl-tRNA--protein transferase 1", "aln": "------MSLSIVSYYGSQQS-KCGYCAGANC--------------------------SLSHGMHAYQLDCRDYQDLIDRGWRRCGYYCYKLRNQETCCPCYTIKCNGLEFKLSKSNKRILRRINRFLRD-----GKRESKPEAGDGDGEADADYAIVAPEVTASEPQPQLPDKSPPVINVEQVASLATAQRKPTKQATAAAVEAPTLGSNKSSLLSSSAAAP-------ISNKPCKKAKQMRLDRRLAKLGDSASYSTKS-----------------LTQEKTLRDFLNTDS-ETNKHRLKLRLIHVY--DDEFRRTLPQSFALYKKYQISIHNDPPKDQDAY---------------------------------------------KEHLQATPLQNEKPWDGPEMGYGSFHQQYWLD--DKLIAVGVIDILPGCVSSVYFFYDPDYSFLSLGTYGSLREIELVQSLAEKVPSLKYYYMGFYIHSCPKMRYKGKLSPSYLLCPETYEWLPLTDVIRAKLDEHKYQRLNEDPAARDVNEFLMEHLDEVKLLLGGRTRTDYKHFRQLRGTVSDDDIIIEYSKLVG-KECARRMLYVK---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P16639-1", "uniprot_id": "ATE1_YEAST", "id": "P16639-1", "name": "Arginyl-tRNA--protein transferase 1", "aln": "---MSDRFVIWAPSMHNEPAAKCGYCHGNKGGNMDQLFALDSWAHRYMNKMDVVKIENCTIGSFVEHMDVATYDRMCNMGFRRSGKFLYKVDPLRNCCRLYTIRTAPQELNMTKELKKCISRFATRITS-------------EDYCPAAVASSDFVGKIVNAEMNSKTFYTRFEPALYSEEKYHLFVKYQEKVHQDYNNS-------PKSFKRFLCDTPFGPEAVLGTQESWEQLNNWQRMKPGEKLKHMGPVHECYYYEG---------------------KLIAITVSDILPSGISSVYFIWDPDYSKWSLGKLSALRDLAIIQRTNLQYYYLG-----------------------------------------------------YYIEDCPKMNYKANYGAEVLDVCHSKYIPLKPIQDMISRGKLFVIGEEETKVTKELYLVDSETGRGEGFPTDNVVKYKNIAEEIYGVGGCAFKSANESALELKELYGIPYEEEDLDTIYHLKEHNGHAPNGIPNVVPGLLPLWELLDIMQSGKITDLEGRLFLFEIETEGIRPLINFYSEPPNVKKRICDVIRLFGFETCMKAVILYSEQM", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .: :**** . . : * . : *: : : *:**.* : ** ..** ***: ::: :*. *: : :: : . . . .. : : :. . .: . : :. . .. . * * .: :.:: .: : . .* : . : . : : .. : :: :: : .: * . *.: .. : *. .:*: * : :: :.* * . * . :: :.: *: : : .*. ::: . * : : : . : .: .: . . . : : *.* : * . :: ", "identical_positions": 36, "similar_positions": 125, "identity": "6.0%" }, { "cls_id": "homologset.agr.RGD:1309336", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U317-1", "uniprot_id": "FIP1_RAT", "id": "Q5U317-1", "name": "Pre-mRNA 3'-end-processing factor FIP1", "aln": "------------------------------------MSAGEVERLV-ELSGGTGGD--------------EEEEWLYG------------GPWDVHVHSDLAKDLDENEVERPEEENASANPPSGIEEEAAENGVAKPKVTETED-DSDSDSDDDEDDVHVTIGD----IKTGAPQYGSYGTAPVNLN--IKAGG-RVYGNTGTKVKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGFNEDTWKAYCEKQKRIRMGLEVIPVTSTTNKIT---------------------------VQQGRTGNSEKEAALPS--TKAEFTSPPSLFKTGLPPSR------------------------------------RLPGAIDVIG-QTITISRVEGRRRAN-ENSNIQVLSDRSATEVDNNFSK-PPPFFPPGAPPTHLPPPPFLPPPPTVSTAPP----LIPPP---------GFPPPP-----GAPPPSLIPTIES------GHSSGYDSRSARAFPYGNVAFP---HLTSSAPSWPSLVDTTKQWDYYARREKDRDRDRERDRDRERERDRDRERERTRERERERDHSPTPSVFN-----SDEERYR-YREYAERGYERH--RASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPVPEQESTEAAPAE-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D824-1", "uniprot_id": "FIP1_MOUSE", "id": "Q9D824-1", "name": "Pre-mRNA 3'-end-processing factor FIP1", "aln": "------------------------------------MSAGEVERLV-ELSGGTGGD--------------EEEEWLYG------------GPWDVHVHSDLAKDLDENEVERPEEENASANPPSGIEEEAAENGVAKPKVTETED-DSDSDSDDDEDDVHVTIGD----IKTGAPQYGSYGTAPVNLN--IKAGG-RVYGNTGTKVKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGFNEDTWKAYCEKQKRIRMGLEVIPVTSTTNKIT---------------------------VQQGRTGNSEKEAALPS--TKAEFTSPPSLFKTGLPPSRNSTSSQSQTSTASRKASSSVGKWQDRYGRAESPDLRRLPGAIDVIG-QTITISRVEGRRRAN-ENSNIQVLSDRSATEVDNNFSK-PPPFFPPGAPPTHLPPPPFLPPPPTVSTAPP----LIPPPGIPITVPPPGFPPPP-----GAPPPSLIPTIES------GHSSGYDSRSARAFPYGNVAFP---HLTSSAPSWPSLVDTTKQWDYYARREKDRDRDRERDRDRERERDRDRERERTRERERERDHSPTPSVFN-----SDEERYR-YREYAERGYERH--RASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPVPEQESTEAAPAE-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6UN15-1", "uniprot_id": "FIP1_HUMAN", "id": "Q6UN15-1", "name": "Pre-mRNA 3'-end-processing factor FIP1", "aln": "------------------------------------MSAGEVERLVSELSGGTGGD--------------EEEEWLYG------------GPWDVHVHSDLAKDLDENEVERPEEENASANPPSGIEDETAENGVPKPKVTETED-DSDSDSDDDEDDVHVTIGD----IKTGAPQYGSYGTAPVNLN--IKTGG-RVYGTTGTKVKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGFNEDTWKAYCEKQKRIRMGLEVIPVTSTTNKITAEDCTMEVTPG----AEIQDGRFNLFKVQQGRTGNSEKETALPS--TKAEFTSPPSLFKTGLPPSRNSTSSQSQTSTASRKANSSVGKWQDRYGRAESPDLRRLPGAIDVIG-QTITISRVEGRRRAN-ENSNIQVLSERSATEVDNNFSK-PPPFFPPGAPPTHLPPPPFLPPPPTVSTAPP----LIPPP---------GFPPPP-----GAPPPSLIPTIES------GHSSGYDSRSARAFPYGNVAFP---HLPGSAPSWPSLVDTSKQWDYYARREKDRDR--ERDRDRERDRDRDRERERTRERERERDHSPTPSVFN-----SDEERYR-YREYAERGYERH--RASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTEATPAE-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5XJD3-1", "uniprot_id": "FIP1_DANRE", "id": "Q5XJD3-1", "name": "Pre-mRNA 3'-end-processing factor FIP1", "aln": "------------------------------------MSAEEADKTT--TTDASAGD--------------EEEEWLYGDEGESKETEEEEAKLTAAISATSTTPVAEDAPTTTNNSSDSATPPT--TTTTTGNGVASQEEAPGEDEDSESDSDDDDDDVRVTIGD----IKTGAPQYTGYGGTPVNLN--IKSAGSRAYG-AGAKVKGVDLEAPGSINGVPVLEADMESFEEKPWRKPGADLSDYFNYGFNEDTWKAYCEKQKRLRMGLDVLNIGSTTSKIS---------------------------VQQGRTGNNEKEITIPAHASKAEFTSPSNLYKAGLNQGRISPPHWAGPPSQ------------------DLSYYTKTPGTIDVIGGQTATISRVEGRRRHNLEGNNIQVISEHSSSEVEPEVQKMPPPFFPPGPLPPNIPPPPFLPPP--VSQAPP----LIPPHRMPITVPPPNFPPPT-----GGPPPSLIPTLDNS-----GHPGGYDGRPVAPYPFPTGGFPP--PMQGAVNPWPGLMENPKQWDYYPRRDK--------------EREKERERERQRDRGHERDHSPNAGPYNSMAMCSDEERYRSYRDYGDRGYERHRERASREKEERHGGRRHREKEEGRHKSSRSSSRRRHESEEGDSHRRHKHKKSKRSKEGKEPSEERSADQENQEAME-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VN31-1", "uniprot_id": "Q9VN31_DROME", "id": "Q9VN31-1", "name": "", "aln": "MADDTNEDSWLYGTSNPDSTTGELGNGGDSLTAEHESAAAEAQALAELVAGEKPGASAGTNSTEDSPRCPKEEVPEYSEFDDPAQEMEEDEDALPNTDSRSRRERDRERDRGRCADRADARSSPDPEDDEMSDGPAARRERNGSG-SDDDEDDDSDDDINVVIGD----IKQAPSTYNIKQRPNLLAGGTGAAGDKAKPAGQAGKFSIEDFEGAGTINGVAVHEFSIDSLEEKPWRKPGADITDYFNYGFNEETWRAYCERQKRFRVAESGVGLASLTQNVNQNAPIGILTDGGMGMGPPGMHSIQSMVGMGGESGMQMPPPGMPPPMMQHQSRSGMGLMQRPPRPISTTGGDRGGDRERAVKEN-AIQVMTAECREYSRGGLGPMAPNFPLPGASEEPFFHEPEPFDYGYEPTQESQWNNDNAGWVPSGIKELTPGHAHMQQPPPGMPPPGMSVPPPQMGGPPPNLRGIMPPN--MRMPPNMNMGPPPGMMMGGNAPPQMRMGMAPPQRLAMGDRGAYDDDRERRRREKEKLLKKDQLRKDFLDMLRERHDIERHTRWYDIKKKFEADPRYRALDSSYREEYFEDYLHLLKEEKRKERDLKERERH-----RDKERSRDKDKDKDKEKDKDK-DKDKEKDKEKDKDKDKEKEKDKESSRRERSRSREKSSRRKSKSREKDRSERSSKSSSSNTGGSSSRSEKKKSHRKDKEEDD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P45976-1", "uniprot_id": "FIP1_YEAST", "id": "P45976-1", "name": "Pre-mRNA polyadenylation factor FIP1", "aln": "--------------------------MSSSEDEDDKFLYGSDSELALPSSKRSRDD--------------EADAGASSN-----PDIVKRQKFDSPVEETPATARDDRSDEDIYSDSSDDDSDSDLEVIISLGPDPTRLDAKLLDSYSTAATSSSKDVISVATDVSNTITKTSDERLITEGEANQGVTATTVKATESDGNVPKAMTGSIDLDKEGIFDSVGITTIDPEVLKEKPWRQPGANLSDYFNYGFNEFTWMEYLHRQEKLQQDYNPRRILMGLLSLQ----------------------------QQGKLNSAN------------------------------------------------------------------------------------DTDSNLGNIIDNNNNVNNANMSNLNSNMGN----SMSGTPNPPAPPMHPSFPPLPMFGSFPP------------------------------FPMPGMMPPMNQ-------QPNQNQNQNSK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . : . . : : . . . . . . . . . ....* : *. . * . . . *:: * ::.* : . : :::****:***:::********* ** * .:*:::: . : .: *. . . : . .: . : . : *. * * .. ** . * : : . . :. ", "identical_positions": 33, "similar_positions": 73, "identity": "4.62%" }, { "cls_id": "homologset.agr.RGD:1309337", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZJ70-1", "uniprot_id": "D3ZJ70_RAT", "id": "D3ZJ70-1", "name": "", "aln": "-------------------------------------MWPLVATIACLTLALSGGISRDYPKILNGTNGTSGFLPGGYTCLPHSQPWQAALLVRG---RLLCGGVLVHPKWVLTAAHCRKDGYTVHLGKHALGR--VENGEQAMEVVRSIPHPEYQVSPTHLNHDHDIMLLELKSPVQLSNHVRTLQLSADDCLPTGTCCRVSGWGTTTSPQVNYPKTLQCANIELRSDEECRQVYPGK---ITANMLCAGTKEGGKDSCEGDSGGPLICNGKLYGIISWGDFPCGQPNRPGVYTRVSKYLRWIQGTIRN--TPEQGWTKGTQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CGR6-1", "uniprot_id": "Q8CGR6_MOUSE", "id": "Q8CGR6-1", "name": "", "aln": "-------------------------------------MWPLVATIACLTLALSEGISRDYPKILNGTNGTSGFLPGGYTCLPHSQPWQAALLIRG---RLLCGGVLVHPKWVLTAAHCRKDGYTVHLGKHALGR--VENGEQAMEVVRSIPHPEYQVTPTHLNHDHDIMLLELKSPVQLSSHVRTLKLSADDCLPTGTCCRVSGWGTTTSPQVNYPKTLQCANIELRSDEECRQVYPGK---ITANMLCAGTKEGGKDSCEGDSGGPLICNGKLYGIISWGDFPCGQPNRPGVYTRVSKYLRWIREIIRN--TPEQRWTKGTQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UKR3-1", "uniprot_id": "KLK13_HUMAN", "id": "Q9UKR3-1", "name": "Kallikrein-13", "aln": "-------------------------------------MWPLALVIASLTLALSGGVSQESSKVLN-TNGTSGFLPGGYTCFPHSQPWQAALLVQG---RLLCGGVLVHPKWVLTAAHCLKEGLKVYLGKHALGR--VEAGEQVREVVHSIPHPEYRRSPTHLNHDHDIMLLELQSPVQLTGYIQTLPLSHNNRLTPGTTCRVSGWGTTTSPQVNYPKTLQCANIQLRSDEECRQVYPGK---ITDNMLCAGTKEGGKDSCEGDSGGPLVCNRTLYGIVSWGDFPCGQPDRPGVYTRVSRYVLWIRETIRKYETQQQKWLKGPQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1ZA64-1", "uniprot_id": "A1ZA64_DROME", "id": "A1ZA64-1", "name": "trypsin", "aln": "----------------------------------------MSLRLGLFLLAALG------VVILTDSASISTHIVGGDQADIADFPYQVSVRLETYMLLHICGGSIYAPRVVITAAHCIKGRYASYIRIVAGQNSIADLEEQGVKVSKLIPHAGYN----KKTYVNDIGLIITREPLEYSALVQPIAVALEAP-PSGAQAVVSGWGKRAEDDEALPAMLRAVELQIIEKSTCGAQYLTKDYTVTDEMLCAGYLEGGKDTCNGDSGGPLAVDGVLVGVVSWG-VGCGREGFPGVYTSVNSHIDWIEEQAEAYL-----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VQ98-1", "uniprot_id": "Q9VQ98_DROME", "id": "Q9VQ98-1", "name": "trypsin", "aln": "------------------------------------------MFVQWIFLAFSVT--------VVSSNWIPERIVGGDLITILSVPWQASILRLG---RFHCGAAIYSEDIVITAAHCLTDRETEFLSVRVGSS-FTFFGGQVVRVSSVLLHEEYD-----QSWSNDIAVMRLQSKLRLGSAVSVIPLADTPP-ASGSPATVSGWGAIG-FKKNYPMSILSASVDIVDQDQCRRSYGRK---ITKDMICAAAP--GKDACSGDSGGPLVSGNKLVGIVSFG-KECAHPEYPGVYANVAELKPWILGAIERITKSE--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VS87-1", "uniprot_id": "Q9VS87_DROME", "id": "Q9VS87-1", "name": "Peptidase S1 domain-containing protein", "aln": "MTSNLSGIVVIANLWILVVGGQSKNWSGYYVDNGTHYLLYEGPRIKPQTFLPGNISTNPAINALEAQDYLPTRIVNGKKIKCSRAPYQCALHYNN---YFICGCVILNRRWILTAQHCKIGNPGRYTVRAGSTQ--QRRGGQLRHVQKTVCHPNYS----EYTMKNDLCMMKLKTPLNVGRCVQKVKLPSTRTKRFPKCYLASGWGLTSANAQNVQRYLRGVIVCKVSRAKCQQDYRGTGIKIYKQMICAKRK--NRDTCSGDSGGPLVHNGVLYGITSFG-IGCASAKYPGVYVNVLQYTRWIKKVAKKY------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IQ89-1", "uniprot_id": "Q8IQ89_DROME", "id": "Q8IQ89-1", "name": "Peptidase S1 domain-containing protein", "aln": "MYQNFGSESEGR--------ERDPSWSGYYKDNGTHYLLYGKPEDIAPTPNFGNISSNPFINALEAQESFPTRIVNGKRIPCTEAPFQGSLHYEG---YFVCGCVIINKIWILTAHHCFFGPPEKYTVRVGSDQ--QRRGGQLRHVKKIVALAAYN----DYTMRHDLAMMKLKSPVYFGKCVRPVKLPSTKTTKFPKKFVVSGWGITSANAQNVQRYLRRVQIDYIKRSKCQKMYKKAGLKIYKDMICASRT--NKDSCSGDSGGPLTSRGVLYGIVSWG-IGCANKNYPGVYVNCKRYVPWIKKVIHKY------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : .* *:* :: ** : ::** ** . * .* : * . :*: :: : : : : :. .**** : . : . * * : :*:** .:*:*.******* * *: *:* *. ****. ** . ", "identical_positions": 42, "similar_positions": 41, "identity": "13.0%" }, { "cls_id": "homologset.agr.RGD:1309339", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZG81-1", "uniprot_id": "D3ZG81_RAT", "id": "D3ZG81-1", "name": "RING-type E3 ubiquitin transferase", "aln": "MSMPLHQISAIPSQDAISARVYRS-KTKDKE---QNEKTLGHSMSHPSNISKAGSSP-PSTTAPVSAFSRTSVTPSNQDICRICHCEGDDESPLITPCHCTGSLHFVHQACLQQWIKSSDTRCCELCKYEFIMETKLKPLRKWEKLQMTASERRKIMCSVTFHVIAITCVVWSLYVLIDRTAEEIKQGQVTGILEWPFWTKLVVVAIGFTGGLLFMYVQCKVYLQLWKRLKAYNRVIYVQNCPE-----------TSKKNIFEK--------SALTEPTLENKEGHGMCHST------------------------------------------TNSS-CTEPED------------TGAEIINV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DBD2-1", "uniprot_id": "MARH8_MOUSE", "id": "Q9DBD2-1", "name": "E3 ubiquitin-protein ligase MARCHF8", "aln": "MSMPLHQISAIPSQDAISARVYRS-KTKDKE---QNEKTLGHSMSHPSNISKAGSSP-PSTTAPVSAFSRTSVTPSNQDICRICHCEGDDESPLITPCHCTGSLHFVHQACLQQWIKSSDTRCCELCKYEFIMETKLKPLRKWEKLQMTASERRKIMCSVTFHVIAITCVVWSLYVLIDRTAEEIKQGQVTGILEWPFWTKLVVVAIGFTGGLLFMYVQCKVYLQLWKRLKAYNRVIYVQNCPE-----------TSKKNIFEK--------SALTEPTLENKEGHGMCHST------------------------------------------TNSS-CTEPED------------TGAEIINV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5T0T0-1", "uniprot_id": "MARH8_HUMAN", "id": "Q5T0T0-1", "name": "E3 ubiquitin-protein ligase MARCHF8", "aln": "MSMPLHQISAIPSQDAISARVYRS-KTKEKEREEQNEKTLGHFMSHSSNISKAGSPPSASAPAPVSSFSRTSITPSSQDICRICHCEGDDESPLITPCHCTGSLHFVHQACLQQWIKSSDTRCCELCKYEFIMETKLKPLRKWEKLQMTSSERRKIMCSVTFHVIAITCVVWSLYVLIDRTAEEIKQGQATGILEWPFWTKLVVVAIGFTGGLLFMYVQCKVYVQLWKRLKAYNRVIYVQNCPE-----------TSKKNIFEK--------SPLTEPNFENKHGYGICHSD------------------------------------------TNSSCCTEPED------------TGAEIIHV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B8A530-1", "uniprot_id": "B8A530_DANRE", "id": "B8A530-1", "name": "RING-type E3 ubiquitin transferase", "aln": "MNMPLHQISVIP-RDVTSSRVCSSGKAKEKDK--QNEKPLGHSASRSSNISKAGSPT--SVNAPCS-FPRSSVTPSNQDICRICHCEGDDESPLITPCHCTGSLRFVHQACLQQWIKSSDTRCCELCKYDFIMETKLKPLRKWEKLQMTASERRKIMCSVTFHVIAITCVVWSLYVLIDRTAEEIKQG----ILEWPFWTKLVVVAIGFTGGLVFMYVQCKVYIQLWRRLKAYNRVIYVQNRPE-----------TCKIKVFDK--------PSLLEPNLENKEALVPAQSD------------------------------------------TNSSQYTETED------------YSMEILHV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VSX7-1", "uniprot_id": "Q9VSX7_DROME", "id": "Q9VSX7-1", "name": "E3 ubiquitin-protein ligase MARCH8", "aln": "----------MPCDNAKTSS--------------DIEHVDWNSGQHYANVRFGSGSS--------------QASQNSGDICRICHCESDPQNPLLTPCYCSGSLKYVHQACLQQWLTASETNSCELCKFPFIMHTKIKPFNEWRSLDISGIERRRLCYSVLFHCAAALCVIWSLCVLIERAADDVQRG----LIDWPFWTKLAVVTVGLTGGIVFMYIQCKAYLHLCHRWKARNRILLIQNAPEKIHPVAPPSPVAAHHQHFSEPLAHAGSTSGAVEINASGAAGGYCAHEANCASMDNGGGGAEMGLHQQMQRLLNASPHHMLQMAAELEVPHSSSSACTQTEDGHGHQRHQQMQQSGQQLGQVAVAANIECSQSQHNYDRDWALDDVVSQISSFRPCPQGSGSMTPFHDSIHNVLEHSEGSSRGSATDLCAGSRQDLSASGISTDTGREHALQLSSFSGSGEHKAPSISSGVSHAVANGLGGFVYKPHQTKRYSNSSIFLENRDVLSDQTSVGPDTAVHPYDYSTPPKIDYRHSGIMGVDLPIGCCTTDCLGGQPTKEELRRYSDPKLKAGEADTVLDIDLPTSPLSPPAAYASSQQKQRNSHQLVISSSFDRGVNGVSSSKSSRGYGPSDAQVDRSRLSFKSLPNLSSSCESLLQK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* :. :: : *: : .: :*: ..... . : .. *********.* :.**:***:*:***::*********:.:*:*..*****: ***.**:**:.:*..*:::. ***:: ** ** * **:*** ***:*:*:::::* :::*******.**::*:***::***:***.*::* :* ** **:: :** ** :.: : *.: . * . .. . .:. :.** *:.** . :: :* ", "identical_positions": 104, "similar_positions": 96, "identity": "15.78%" }, { "cls_id": "homologset.agr.RGD:1309340", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WUI1-1", "uniprot_id": "MK11_MOUSE", "id": "Q9WUI1-1", "name": "Mitogen-activated protein kinase 11", "aln": "MSGPRAG-FYRQELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQSLIHARRTYRELRLLKHLKHENVIGLLDVFTPATS---IEDFSEVYLVTTLMGADLNNIVKCQALSDEHVQFLVYQLLRGLKYIHSAGIIHR---------------------------DLKPSNVAVNEDCELRILDFGLARQADEEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGNDYIDQLKRIMEVVGTPSPEVLAKISSEHARTYIQSLPPMPQKDLSSVFHGANPLAIDLLGRMLVLDSDQRVSAAEALAHAYFSQYHDPDDEPEAEP-YDESVEAKERTLEEWKELTYQEVLSFKPLE------------------------PSQLPGTHEIEQ----------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2KB06-1", "uniprot_id": "A0A0G2KB06_RAT", "id": "A0A0G2KB06-1", "name": "mitogen-activated protein kinase", "aln": "MSGPRAG-FYRQELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQSLIHARRTYRELRLLKHLKHENVIGLLDVFTPATS---IEDFSEVYLVTTLMGADLNNIVKCQALSDEHVQFLVYQLLRGLKYIHSAGIIHRVGAAEGEGHPLCLGSWPYHTHALCTLQDLKPSNVAVNEDCELRILDFGLARQADEEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGNDYIDQLKRIMEVVGTPSPEVLAKISSEHARTYIQSLPPMPQKDLSSVFHGANPLAVDLLGRMLVLDSDQRVSAAEALAHAYFSQYHDPDDEPEAEP-YDESVEAKERTLEEWKELTYQEVLSFKPLE------------------------TSQLPGTHEIEQ----------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q15759-1", "uniprot_id": "MK11_HUMAN", "id": "Q15759-1", "name": "Mitogen-activated protein kinase 11", "aln": "MSGPRAG-FYRQELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQSLIHARRTYRELRLLKHLKHENVIGLLDVFTPATS---IEDFSEVYLVTTLMGADLNNIVKCQALSDEHVQFLVYQLLRGLKYIHSAGIIHR---------------------------DLKPSNVAVNEDCELRILDFGLARQADEEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVGTPSPEVLAKISSEHARTYIQSLPPMPQKDLSSIFRGANPLAIDLLGRMLVLDSDQRVSAAEALAHAYFSQYHDPEDEPEAEP-YDESVEAKERTLEEWKELTYQEVLSFKPPE------------------------PPKPPGSLEIEQ----------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O62618-1", "uniprot_id": "MK38A_DROME", "id": "O62618-1", "name": "Mitogen-activated protein kinase p38a", "aln": "MSVSITKKFYKLDINRTEWEIPDIYQDLQPVGSGAYGQVSKAVVRGTNMHVAIKKLARPFQSAVHAKRTYRELRLLKHMDHENVIGLLDIFHPHPANGSLENFQQVYLVTHLMDADLNNIIRMQHLSDDHVQFLVYQILRGLKYIHSAGVIHR---------------------------DLKPSNIAVNEDCELRILDFGLARPTENEMTGYVATRWYRAPEIMLNWMHYDQTVDIWSVGCIMAELITRRTLFPGTDHIHQLNLIMEMLGTPPAEFLKKISSESARSYIQSLPPMKGRSFKNVFKNANPLAIDLLEKMLELDAEKRITAEEALSHPYLEKYAEPSVEQTSPP-YDHSFEDMDLPVDKWKELIYKEVTNFKPP-------------------------PSYAQVLKDVK-----------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32485-1", "uniprot_id": "HOG1_YEAST", "id": "P32485-1", "name": "Mitogen-activated protein kinase HOG1", "aln": "--MTTNEEFIRTQIFGTVFEITNRYNDLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTAVLAKRTYRELKLLKHLRHENLICLQDIF--------LSPLEDIYFVTELQGTDLHRLLQTRPLEKQFVQYFLYQILRGLKYVHSAGVIHR---------------------------DLKPSNILINENCDLKICDFGLARIQDPQMTGYVSTRYYRAPEIMLTWQKYDVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVINTICSENTLKFVTSLPHRDPIPFSERFKTVEPDAVDLLEKMLVFDPKKRITAADALAHPYSAPYHDPTDEPVADAKFDWHFNDADLPVDTWRVMMYSEILDFHKIGGSDGQIDISATFDDQVAAATAAAAQAQAQAQAQVQLNMAAHSHNGAGTTGNDHSDIAGGNKVSDHVAANDTITDYGNQAIQYANEFQQ", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * : :: * :*:.: :.*.*** **:* *..* **:**: :**.: : *:******:****: ***:* * *:* :. :.::*:** * .:**:.::: : *..:.**:::**:******:****:*** ******: :**:*:*:* ****** : :*****:**:********.* :*: *****.***:**:: :.****.*::.*:. * :::*:*. :.: .*.** : .:: *** :.. *: .:* *:*** :** :*..:*::* :**:*.* * :* * : . :* .: : .:: *: : *.*: .*: . ::: ", "identical_positions": 142, "similar_positions": 125, "identity": "30.08%" }, { "cls_id": "homologset.agr.RGD:1309341", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U1Y0-1", "uniprot_id": "TM192_RAT", "id": "Q5U1Y0-1", "name": "Transmembrane protein 192", "aln": "--MAAGGRLEDGS---LDILQSTDDDPLLDTQPLPHHSLHAHFRPRFHPLPTVIIANLLLLIHVVFVTLAFLTGVLCLYPDPNEDKCPENYTNPLKVQTAIILGKVILWILHLLFERYIQYHHRKVRSRGYSQIYRSTRHLKALALTIHSSGNTALLLLLCVQYSFPEPNK---------LYLELILAVLALELICSLSCLVLYTVKIRRFNKAKPQPDVLEEEKCYAYPSNIASETGFRTVSSLEEIVEKQGDIIVYLKRHNALLSKRLLELAT-----QPART----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CXT7-1", "uniprot_id": "TM192_MOUSE", "id": "Q9CXT7-1", "name": "Transmembrane protein 192", "aln": "--MAAAGRLEDSS---LDILQSMDDDPLLDTQPLPHHSLQAQFRPRFHPLPTVIIANLLLLIHVVFVVLAFLTGVPCLYPNPTEDKCPENYTSPLKVQTAIILGKLILWILHLLFERYVQYHHRKVRSRGYSQIYRSTRHLKTLALTIHSSGNTALLLLLCVQHSFPEPSK---------LYLELILAVLALELICSLSCLILYIVKIRRFNRAKPLPDVLEEEKIYAYPSNTASETGFRTVSSLEEIVEKQEDIIVYLKRHNALLSKRLLELAT-----QPART----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IY95-1", "uniprot_id": "TM192_HUMAN", "id": "Q8IY95-1", "name": "Transmembrane protein 192", "aln": "--MAAGGRMEDGS---LDITQSIEDDPLLDAQLLPHHSLQAHFRPRFHPLPTVIIVNLLWFIHLVFVVLAFLTGVLCSYPNPNEDKCPGNYTNPLKVQTVIILGKVILWILHLLLECYIQYHHSKIRNRGYNLIYRSTRHLKRLALMIQSSGNTVLLLILCMQHSFPEPGR---------LYLDLILAILALELICSLICLLIYTVKIRRFNKAKPEPDILEEEKIYAYPSNITSETGFRTISSLEEIVEKQGDTIEYLKRHNALLSKRLLALTSSDLGCQPSRT----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NYE7-1", "uniprot_id": "TM192_DANRE", "id": "Q6NYE7-1", "name": "Transmembrane protein 192", "aln": "MVMESGRTSAYGNNTNVDFTQSTDDDPLIDGPLVSQDALESAIKREFQTLSTHWAVGVLSFLHVVYVVVCIVITVFCWISDEHTSECTAALNG-IDSKTVVLLGKVALWVVVFIYDRVVQRRHSAVRRKGYLDFYRMTKGIKSLPLLIHSAGNAAILTVIAPSSLLDANVKN--------LSVYLLLAIICLELLLTIICLLRYTVHVVKFNRKKPHPDVTEEERSYGCSSDAHTETGFRDGSSLEDVVEKQADLIDYLKQHNSVLSRRILTLTG-----QQIRA----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VEH2-1", "uniprot_id": "Q9VEH2_DROME", "id": "Q9VEH2-1", "name": "Transmembrane protein 192", "aln": "--MEQPATGGAAVQPGVSPAHIHDTDQLLDPVLFSNDNGSYKLN-----------TVPAFSLHLVISTAISIVGIVLAASFPTDRRC--------DAYFIMLYLRATFWVITYLFDHFVKKQHDNLRMQGYHDFHRETNMQKGIPLQLVSLWNSMLLAVQALIHHFYAENFWEHCAAGWLSPVSYVTAFTVAENLVLAVSHSLYIDKVRKFNSAKLAPDVLR-----GADRAGGSLGLMQPGGDTEELLEKQADLIAYLRDHTHKLNQKLHQMQTN---VRPVRAPQIP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . :. : : * *:* ..:. :. . :*:* . : : . .* . :: : :*:: : : :: :* :* :** ::* *. * :.* : * *: :* : . : : : *. * : . * :: :** * **: . . : :: .. *:::*** * * **: *. *.::: : : *: ", "identical_positions": 38, "similar_positions": 73, "identity": "13.15%" }, { "cls_id": "homologset.agr.RGD:1309343", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "F7FHT4-1", "uniprot_id": "F7FHT4_RAT", "id": "F7FHT4-1", "name": "Semaphorin-3C", "aln": "MSKSEEMALREICVLVGVFICS----ICVQGSSQPQARVYLT----------FDELRETKTSEYFSLSHQQLDYRILLMDEDQDRIYVGSKDHILSLNINNISQEPLS---VFWPASTIKVEECKMAGKDPTHGCGNFVRVIQTFNR-THLYVCGSGAFSPVCTYLNRGRRSEDQVFMIDSKCESGKGRCSFNPNVNTVSVMIN-------EELFSGMYIDFMGTDAAIFRSLTKRNAVR--------TDQHNSKWLSEPMFVDAHVIPDGTDPNDAKVYFFFKERLTDNNRSTKQIHSMVARICPNDTGGQRSLVNKWTTFLKARLVCSVTDEDGPETHFDELEDVFLLETDNPRTTLVYGIFTTSSSVFKGSAVCVYHLSDIQTVFNGPFAHKEGPNHQLISYQG-RIPYPRPGTCPGGAFTPNMRTTKDFPDDVVTFIRNHPLMYNSIYPIHRRPLIVRIGTDYKYTKIAVDRVNAADGRYHVLFLGTDRGTVQKVVVLPTNSSASGELILEELEVFKNHVPITTMKISSKKQQLYVSSNEGVSQVSLHRCHIYGTACADCCLARDPYCAWDGHSCSRFYPTGKRRSRRQDVRHGNPLTQCRGFNLKGMRAYRNAAEIVQYGVRNNSTFLECAPKSPQASIKWLLQKDKDRRKEVKLN--ERIIATSQGLLIRSVQDSDQGLYHCIATENSFKQTIAKINFKVLDSEMVAVVTDK-WSPWTWAGSVRALPFHPKDILGAFSHSEMQLINQYCKDTRQQQQLGEEPQKMRGDYGKLKALINSRKSRNRRNQLPES", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62181-1", "uniprot_id": "SEM3C_MOUSE", "id": "Q62181-1", "name": "Semaphorin-3C", "aln": "------MAFRAICVLVGVFICS----ICVRGSSQPQARVYLT----------FDELRETKTSEYFSLSHQQLDYRILLMDEDQDRIYVGSKDHILSLNINNISQEPLS---VFWPASTIKVEECKMAGKDPTHGCGNFVRVIQTFNR-THLYVCGSGAFSPVCTYLNRGRRSEDQVFMIDSKCESGKGRCSFNPNVNTVSVMIN-------EELFSGMYIDFMGTDAAIFRSLTKRNAVR--------TDQHNSKWLSEPMFVDAHVIPDGTDPNDAKVYFFFKERLTDNNRSTKQIHSMIARICPNDTGGQRSLVNKWTTFLKARLVCSVTDEDGPETHFDELEDVFLLETDNPRTTLVYGIFTTSSSVFKGSAVCVYHLSDIQTVFNGPFAHKEGPNHQLISYQG-RIPYPRPGTCPGGAFTPNMRTTKDFPDDVVTFIRNHPLMYNSIYPIHRRPLIVRIGTDYKYTKIAVDRVNAADGRYHVLFLGTDRGTVQKVVVLPTNSSASGELILEELEVFKNHVPITTMKISSKKQQLYVSSNEGVSQVSLHRCHIYGTACADCCLARDPYCAWDGHSCSRFYPTGKRRSRRQDVRHGNPLTQCRGFNLK---AYRNAAEIVQYGVRNNSTFLECAPKSPQASIKWLLQKDKDRRKEVKLN--ERIIATSQGLLIRSVQDSDQGLYHCIATENSFKQTIAKINFKVLDSEMVAVVTDK-WSPWTWAGSVRALPFHPKDILGAFSHSEMQLINQYCKDTRQQQQLGEEPQKMRGDYGKLKALINSRKSRNRRNQLPES", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99985-1", "uniprot_id": "SEM3C_HUMAN", "id": "Q99985-1", "name": "Semaphorin-3C", "aln": "------MAFRTICVLVGVFICS----ICVKGSSQPQARVYLT----------FDELRETKTSEYFSLSHHPLDYRILLMDEDQDRIYVGSKDHILSLNINNISQEALS---VFWPASTIKVEECKMAGKDPTHGCGNFVRVIQTFNR-THLYVCGSGAFSPVCTYLNRGRRSEDQVFMIDSKCESGKGRCSFNPNVNTVSVMIN-------EELFSGMYIDFMGTDAAIFRSLTKRNAVR--------TDQHNSKWLSEPMFVDAHVIPDGTDPNDAKVYFFFKEKLTDNNRSTKQIHSMIARICPNDTGGLRSLVNKWTTFLKARLVCSVTDEDGPETHFDELEDVFLLETDNPRTTLVYGIFTTSSSVFKGSAVCVYHLSDIQTVFNGPFAHKEGPNHQLISYQG-RIPYPRPGTCPGGAFTPNMRTTKEFPDDVVTFIRNHPLMYNSIYPIHKRPLIVRIGTDYKYTKIAVDRVNAADGRYHVLFLGTDRGTVQKVVVLPTNNSVSGELILEELEVFKNHAPITTMKISSKKQQLYVSSNEGVSQVSLHRCHIYGTACADCCLARDPYCAWDGHSCSRFYPTGKRRSRRQDVRHGNPLTQCRGFNLK---AYRNAAEIVQYGVKNNTTFLECAPKSPQASIKWLLQKDKDRRKEVKLN--ERIIATSQGLLIRSVQGSDQGLYHCIATENSFKQTIAKINFKVLDSEMVAVVTDK-WSPWTWASSVRALPFHPKDIMGAFSHSEMQMINQYCKDTRQQHQQGDESQKMRGDYGKLKALINSRKSRNRRNQLPES", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6Z658-1", "uniprot_id": "A0A8M6Z658_DANRE", "id": "A0A8M6Z658-1", "name": "Semaphorin-3C", "aln": "MGRSGALWVYPLGTSVQLFLLLGLSVSSIHALSSPQPRVFLP----------FQELQKTQSFEHYSLSEKAMDYRILFTDEDQDRMYVGCKDHILSMDINNISQATLK---IFWPASISKVEECQMAGKDPTHGCGNFLRVIQPYNR-THLFICGSGAYSPVCAYVNRGRRPEEQVFQISSRAESGKGRCSFNPQVNTVSVMLN-------QELFSGMYIDFMGTDAAIFRSLTTRNPVR--------TDQHNSKWLSEPLFIDAQLIPDGSDPNDAKLYFFLRERLTDTSGNTKNIHAMVARVCPNDTGGQRSLVNKWTTFLKARMVCSVLEEDGTETHFDELENVFLLETDHPKGLLIFGVFTSTSSVFRGSAVCVYNMADILTVFNGPFAHREGPNFQWVAFQG-RIPYPRPGTCPGGAFTPHIQSTKEFPDDVVTFVRNHPVMFNPIYPVGRKPLVVRTHADYKYTSIAVDQVPAADGHYQVLFLGTDKGTVQKVVVLPSNGSLDEDLILEELEVFKTQSPITNLRISSKKQQLYVSSEHGISQVSLHRCNAYGSACADCCLARDPYCAWDGLSCSRFYPTGKRRSRRQDIMHGNPLTQCRGFNLK---AYRNAVEMTQYGVKNNTTFLECQPKSPQASVKWLIQRDNDRRKEVKLS--DRVVSTNHGLLIRSVHSSDQGLYYCLATENGFKRTLAKIRLQVLSEALVSALSNKQQSPWGWTAN-----LHPKALVSAFSPAETLAMHQYCKERKQMQSLQSIQSPMRGDLGKLKPLLDHRKSRNRRNHLQQD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24323-1", "uniprot_id": "SEM2A_DROME", "id": "Q24323-1", "name": "Semaphorin-2A", "aln": "------MSLLQLSPLLALLLLLCSSVSETAADYENTWNFYYERPCCTGNDQGNNNYGKHGADHVREFNCGKLYYRTFHMNEDRDTLYVGAMDRVFRVNLQNISSSNCNRDVINLEPTRDDVVSCVSKGKSQIFDCKNHVRVIQSMDQGDRLYVCGTNAHNPK-DYVIYANLTHLPRSEYVIGVGLGIAKCPYDPLDNSTAIYVENGNPGGLPGLYSGTNAEFTKADTVIFRTDLYNTSAKRLEYKFKRTLKYDSKWLDKPNFVGSFDIG-------EYVYFFFRETAVEYINCGKAVYSRIARVCKKDVGGKNLLAHNWATYLKARLNCSISGEFP--FYFNEIQSVYQLPSDKSR---FFATFTTSTNGLIGSAVCSFHINEIQAAFNGKFKEQSSSNSAWLPVLNSRVPEPRPGTCVN--------DTSNLPDTVLNFIRSHPLMDKAVNHEHNNPVYYKRDLVFTKLVVDKIRIDILNQEYIVYYVGTNLGRIYKIVQYYRNG-ESLSKLLDIFEVAP-NEAIQVMEISQTRKSLYIGTDHRIKQIDLAMCNRRYDNCFRC--VRDPYCGWDKEAN-------TCRPYELDLLQDVANETSDICDSS---VLKKKIVVTYGQSVHLGCFVKIPEVLKNEQVTWYHHSKDKGRYEIRYSPTKYIETTERGLVVVSVNEADGGRYDCHLGGS------LLCSYNITVDAHRCTPPNK-------------------------SNDYQKIYSDWCHEFEKYKTAMKSWEKKQAQCSTRQNFSSNQHPNEIFRKPNV-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : : ::: . . ..: :: : : . .:. : ** : :**:* :***. *::: ::::***. . : .: .* .* **. ..* *.:****. :: :*::**:.*..* *: .. .. * .:*.::* *:.:: :: *:** :* :*:.***: ....: * :::****.:* *:.: * :***::* .: * ::: :**:* :*.** . *.::*:*:****: **: * :*:*::.*: * :*:.: .:. **:::. : ***** ::: :* :.*** * .:...* :. . *:* ****** . *.::** *:.*:*.**:* :.: ..*: : :. : :: : .* * ::**: * : *:* *. . . :*: :** : .* :.**..::.**:.::. :.*:.* *: * * .*****.** : . *. . *: :. . . : . . :: :. : *:: : .:.* : ... * *:: . . : :*.:**:: **: :* * * * . :: . .. .:* * ::*:: .: : . . :.: .. : : . ::..: .: ", "identical_positions": 151, "similar_positions": 269, "identity": "18.95%" }, { "cls_id": "homologset.agr.RGD:1309345", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "B2GUV8-1", "uniprot_id": "B2GUV8_RAT", "id": "B2GUV8-1", "name": "", "aln": "--------------------------------------------MASPADSCIQFTRHASDVLLNLNRLRSRDILTDVVIVVSREQFRAHKTVLMACSGLFYSIFTDQLKCNLSVINLDPEISPEGFCILLDFMYTSRLNLREGNIMAVMATAMYLQMEHVVDTCRKFIKASEAEMAPALKPPREEFLNSRMLMPHDVMAYRGREVVENNMPLRNTPGCESRAFAPPLYSGLSTPPASYPMYSHLPLSSFLFSDEELRDAP----RMPVANPFPKERALPCDSARPVPNEYSRPTMEVSPSLCHSNIYSPKEAVPEEARSDIHYSVTEGPKPAA-PSARHASYFPCDKAS-----KEEERPSSEDEIALHFEPPNAPLNRKGLVS-PQSPQKSDCQPNSPTESSSSKNACILQASGSPPAKSPTDPKACNWKKYKFIVLNSLNQNAKPEGSEQAELGRLSPRAYPAPPACQPPMEPANLDLQSPTKLSASGEDSTIPQASRLNNIVNRSLAGSPRSSSESHSPLYMHPPKCTSCGSQSPQHTEMCLHTAGPTFPEEMGETQSEYSDSSCENGAFFCNECDCRFSEEASLKRHTLQTHSDKPYKCDRCQASFRYKGN-LASHKTVHTGEKPYRCNICGAQFNRPANLKTHTRIHSGEKPYKCETCGARFVQVAHLRAHVLIHTGEKPYPCEICGTRFRHLQTLKSHLRIHTGEKPYHCEKCNLHFRHKSQLRLH--LRQKHGAITN------TKVQYRVSAADLPPELPKAC-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P41183-1", "uniprot_id": "BCL6_MOUSE", "id": "P41183-1", "name": "B-cell lymphoma 6 protein homolog", "aln": "--------------------------------------------MASPADSCIQFTRHASDVLLNLNRLRSRDILTDVVIVVSREQFRAHKTVLMACSGLFYSIFTDQLKCNLSVINLDPEISPEGFCILLDFMYTSRLNLREGNIMAVMTTAMYLQMEHVVDTCRKFIKASEAEMAPALKPPREEFLNSRMLMPHDIMAYRGREVVENNMPLRNTPGCESRAFAPPLYSGLSTPPASYPMYSHLPLSTFLFSDEELRDAP----RMPVANPFPKERALPCDSARQVPNEYSRPAMEVSPSLCHSNIYSPKEAVPEEARSDIHYSVPEGPKPAV-PSARNAPYFPCDKAS-----KEEERPSSEDEIALHFEPPNAPLNRKGLVS-PQSPQKSDCQPNSPTESCSSKNACILQASGSPPAKSPTDPKACNWKKYKFIVLNSLNQNAKPEGSEQAELGRLSPRAYPAPPACQPPMEPANLDLQSPTKLSASGEDSTIPQASRLNNLVNRSLAGSPRSSSESHSPLYMHPPKCTSCGSQSPQHTEMCLHTAGPTFPEEMGETQSEYSDSSCENGTFFCNECDCRFSEEASLKRHTLQTHSDKPYKCDRCQASFRYKGN-LASHKTVHTGEKPYRCNICGAQFNRPANLKTHTRIHSGEKPYKCETCGARFVQVAHLRAHVLIHTGEKPYPCEICGTRFRHLQTLKSHLRIHTGEKPYHCEKCNLHFRHKSQLRLH--LRQKHGAITN------TKVQYRVSAADLPPELPKAC-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P41182-1", "uniprot_id": "BCL6_HUMAN", "id": "P41182-1", "name": "B-cell lymphoma 6 protein", "aln": "--------------------------------------------MASPADSCIQFTRHASDVLLNLNRLRSRDILTDVVIVVSREQFRAHKTVLMACSGLFYSIFTDQLKCNLSVINLDPEINPEGFCILLDFMYTSRLNLREGNIMAVMATAMYLQMEHVVDTCRKFIKASEAEMVSAIKPPREEFLNSRMLMPQDIMAYRGREVVENNLPLRSAPGCESRAFAPSLYSGLSTPPASYSMYSHLPVSSLLFSDEEFRDV-----RMPVANPFPKERALPCDSARPVPGEYSRPTLEVSPNVCHSNIYSPKETIPEEARSDMHYSVAEGLKPAA-PSARNAPYFPCDKAS-----KEEERPSSEDEIALHFEPPNAPLNRKGLVS-PQSPQKSDCQPNSPTESCSSKNACILQASGSPPAKSPTDPKACNWKKYKFIVLNSLNQNAKPEGPEQAELGRLSPRAYTAPPACQPPMEPENLDLQSPTKLSASGEDSTIPQASRLNNIVNRSMTGSPRSSSESHSPLYMHPPKCTSCGSQSPQHAEMCLHTAGPTFPEEMGETQSEYSDSSCENGAFFCNECDCRFSEEASLKRHTLQTHSDKPYKCDRCQASFRYKGN-LASHKTVHTGEKPYRCNICGAQFNRPANLKTHTRIHSGEKPYKCETCGARFVQVAHLRAHVLIHTGEKPYPCEICGTRFRHLQTLKSHLRIHTGEKPYHCEKCNLHFRHKSQLRLH--LRQKHGAITN------TKVQYRVSATDLPPELPKAC-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PZK1-1", "uniprot_id": "A0A8M9PZK1_DANRE", "id": "A0A8M9PZK1-1", "name": "", "aln": "MPHSLQQKHAQQMLLLCQGINGTREDGPAPHSWSHKRSYSDLEKMACAADSCIQFTRHASDVLLNLNRLRSRDILTDVTILVNRQQFRAHKTVLMACSGLFYSIFTDSHKCNLNAISLDPKVDPEGFAILLEFMYTSRLALKESLIMAIMNTAIYLQMDHVVDTCHRFIKSSD----SSIKLPREDFLVSPLLLPQDIHSYRPHEVMDN-VSGRSATFRDGRPYGVCMFNGVNAPNNSY-LYGQFPMQGFPFPLCKLTDTKNTFSDFSKGGIIHHKHCSPSDGNNPVLNDFTRSATSGSSAVCHTGSYSSRELGRDE---DMKRETLEGVVHSIGMSSRKHGFISLAQEQQRESGKEQSSLAEEHLSHQHYSMGISSNGRKTLMSSPQSPLKSDCQPNSPTESSSSKNAALAQALQPPTSQGTSDPKARNWKKYKFIVLN---QSSKEEETNPPDPGMHSP-QRPGLSAFLHHVDSEHPDSKVTTKISEQGEDFPAPQASRLNNIINRSLEGSQRN-IDSHSSLYMNHLKCSSCGSQSPQHSDVCPNTSASRLAEEMSEMHSEYSDSSCENGTYFCNECDSKFAEEEALKRHTLQVHSDKPYKCDRCQAAFRYKGN-LASHKTVHTGEKPYRCNICGAQFNRPANLKTHTRIHSGEKPYKCETCGARFVQVAHLRAHVLIHTGEKPYPCEICGTRFRHLQTLKSHLRIHTGEKPYHCEKCNLHFRHKSQLRLH--LRQKHGAITN------TKIQYRMSSTELPTDLTKAC-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2BIF1-1", "uniprot_id": "A0A8M2BIF1_DANRE", "id": "A0A8M2BIF1-1", "name": "", "aln": "--------------------------------------------MSCAADGCIKFTRHAGDVLFNFNRLRSRNLLTDVTIMVGGQQFRAHKTVLMACSGLFYSMFADNPKSNLSLISLDPKVDPDGFAILLEFMYTSCLTLKDNFIIATLNTATYLQMDHVMETCQRFIDSRG----LCMKQTRTEMLVNRGCLSSEAPFIEA-------LNPQSSVNFSTYTSPNLHYAVSTCTENPTRFYRHLPLP------------------LEPSNPTNPLWQIP-KTTVIAHQQHSLPESGTSARTITNAAVEDGDKERNRPSVLFRSARAEG--------NRKAPLLSSEVEN-----IEACHTGG-----------------------PESPLRSDCQPNSPAESSGCS-----RRPASPPS-SITYAKVHNWKKYKFIVLN----------------------------------STDNSSLTPPHTVSESTN-----QNAEHKGQDNRSTDECIKK--EEHG------------------------SSVHNTFTEES----SMGSTNSAERERVYCNECESEAEKPQWLQ-------DGKPYKCDRCQAMFHYKGNPLSSHKSVHTGEKPYRCNVCGAQFNRPANLKTHSRIHSGEKPYKCETCSSRFVQVAHLRAHVLIHTGEKPYPCDICGTRFRHLQTLKSHLRIHTGEKPYHCENCDLRFRHKSQLRLH--LRQKHGAITN------TKVQYGRTRPELTCP----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V9N4-1", "uniprot_id": "CLAMP_DROME", "id": "Q9V9N4-1", "name": "Transcription factor Clamp", "aln": "---------------------------------------------MEDLTKNIIFTNAINGQPATIQYQTADGTILKQPKIEGQK--------TEQQPTFYYTTNGNGGTVNLAQLATT---DDNKTCYIAQPVGGYNYALVNG---MPLNQGAALGIATVDAQGRIQIVNQN-------KPIAANTISN--------------------ISFKCDVCSDMFPHLALLNAHKR---------------------------------MHTDGEQQQQQQHNAQAGGDSIAVVSAQGLVQAQNIIGNGQMGQIQIVSSDTLEPVQQSVMQQQQHES----KASKCINCGSSMLQ-------------------------------QSKRKGPKQVRCESCMQAEQTAQQQQQLFVAQDGQMAHPVQIISTTPQAQAQLQQIV----------------------------------AAQTGGTTPKREASSGSGHHPVKKRNSQQMTKCQKCNGSGVVLVGQHS------------------------HASHSGVGGSVKQSVTVKTENPSK--PFSCNICGGLFSRYSSLWSHKKLHSGEKNYKCSICGLAFAKAVY-LKNHARIHTGEKPYKCQTCGMQFSQSPHLKNHERTHSGERPYVCGVCDKGFARHATLWNHRRIHTGEKPYKCEICGSAFSQAAHLKNHAKVHSGEKPYKCEICSAAFADRFALKRHRGIHQKYGQTAPRQTSSDGMIVHKQEIPDMEDEAQQEVIIGGL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * **. .. .:: : . : . : . : . ::*: : . ** : . : . : : : * :. : . * : * : * * : : . : : . . : . . : : . : . .: : : : :.* : *:. :*. . . : .. : :: : . . * : : :. . .*. : . . : : ...: ** * . * . * ***. * * * .* :*******:*: ** **.:..:**.* * ****:** * .*. *.: * * * ******** *:***: * : **.* ::*:*****:** *. * .: *: * ::**:* : : : .:: ", "identical_positions": 87, "similar_positions": 125, "identity": "11.21%" }, { "cls_id": "homologset.agr.RGD:1309346", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZHK4-1", "uniprot_id": "D3ZHK4_RAT", "id": "D3ZHK4-1", "name": "RB1-inducible coiled-coil protein 1", "aln": "MKLYVFLVNTGTTLTFDTELTVQTVADLKHAIQSKYKIAVQHQVLVVNGGECMTADRRVCTYSAGTDTNPIFLFNKEMILCDRAPAIPKTTFSTENDMEIKVEESLMMPAVFHTVASRTQLAVEMYEVAKKLCSFCEGLVHDEHLQHQGWAAIMANLEDCSTSYQKLLFKFESIYSDYLQSIEDIKLKLTHLGTAVSVMAKIPLLECLTRHSYRECLGRPDSLNEHEGSEKADMKRSTELVLSPDMPRTTNTSLLTSFHKSVEHVAPDVTDAEQGKELRESCQSTVQQ-EDAPVDAKDSDLPFFNVSLLDWINVQDRPNDVESLVRKCFDSMSRLDPKIIQPFMLECHQTIAKLDNQNMKAIKGLEDRLYALDQMIASCSRLVNEQKELAQGFLANQMRAENLKDASVLPDLCLSHANQLMIMLQNHRKLLDIKQKCTTAKQELANNLHVRLKWCCFVMLHADQDGEKLQALLRLVIELLERVRIVEALSTVPQMYCLAVVEVVRRKMFIKHYREWAGALVKDGKQLYEAEKSKRESFGKLFRKSFLRNRLFKGLDSWPSSFCTQKPRKFDCELPDISLKDLQFLQSFCPSEVQPFLRVPLLCDFEPLHQHVLALHNLVKAAQSLDEMSQTITDLLNEQKVSTSQASPQSAASPRIESTTGITTTTSPKAPPPLTVQDTLYPAACPLEELSPDSIDAHTFDFETVSHPNTEQTVHQASIDLDSLAESPESDFMSAVNEFVIEENLSSPNPISDPQSPEMMVESLYSSVINAIDSRRMQDTSTRGNEGFGDRAALHVQLEKCRVAAQDSHISIQTIKDDLCHFRTFVQKEQCDLSNYLKCTAVEIRNIIDKVKCSLEITLKEKHQQELQSLKIEYECKLNTLEKDSEENVNKILKLKEDLVSLEEALQNKDSEFAIIKHEKDAIVCMQHEKDQKLLEMENIMHTQNSEIKELKQSREMVLEDLKKLH---DEKIESLRAEFQCLEQNHLKELEDTLHIRHTEEFEKVITDHKVSLEKLKKENQQKIDQMLESHASAIQEK-EQQLQELKVKVSDLSDMRCKLEVELALKEAETDEIKILLEESRTQQKETLKSLLEQETENLRTEINKLNQKIHDNSESYQVGLSELRSLMTIEKDQCISELISRHEEESNILKAELDSVTALHHQAFEIEKKLKEQIVELQTKLNSELSALEKQKDEKITQQEEKYKALIQNLEKDKQRLAMNHEQDKEQLIQKLNFEKDEAIQTALDEFKLERELVEKELLEKVKHLENQIAKSPAFESAREDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFNTVLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSEDRARLLEEKKKLEEEVSKLRTSSVLPSAPVLAAPELYGACAPELPGEPERSAMETTDEGRVDSAMETSMMSVQEN--MLSEEKQRIMLLERTLQLKEEENKRLNQRLMSQSLSSVSSRHSEKIAIRDFQVGDLVLIILDERHDNYVLFTVSPTLYFLHSESLPALDLKPGEGASGVSRRPWVLGKVMEKEYCQAKKAQNRFKVPLGTKFYRVKAVSWNKKV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ESK9-1", "uniprot_id": "RBCC1_MOUSE", "id": "Q9ESK9-1", "name": "RB1-inducible coiled-coil protein 1", "aln": "MKLYVFLVNTGTTLTFDTELTVQTVADLKHAIQSKYKIAIQHQVLVVNGGECMAADRRVCTYSAGTDTNPIFLFNKEMILCDRAPAIPKATFSTENDMEIKVEESLMMPAVFHTVASRTQLAVEMYDVAKKLCSFCEGLVHDEHLQHQGWAAIMANLEDCSNSYQKLLFKFESIYSDYLQSIEDIKLKLTHLGTAVSVMAKIPLLECLTRHSYRECLGRPDSLNEHEGSEKAEMKRSTELVLSPDMPRTTNTSLVTSFHKSMEHVAPDPTGTERGKELRESCQSTVQQ-EEASVDAKDSDLPFFNVSLLDWINVQDRPNDVESLVRKCFDSMSRLDPKIIQPFMLECHQTIAKLDNQNMKAIKGLEDRLYALDQMIASCSRLVNEQKELAQGFLANQMRAENLKDASVLPDLCLSHANQLMIMLQNHRKLLDIKQKCTTAKQELANNLHVRLKWCCFVMLHADQDGEKLQALLRLVIELLERVRIVEALSTVPQMYCLAVVEVVRRKMFIKHYREWAGALVKDGKQLYEAEKSKRESFGKLFRKSFLRNRLFKGLDSWPSSFCTQKPRKFDCELPDISLKDLQFLQSFCPSEVQPFLRVPLLCDFEPLHQHVLALHNLVKAAQSLDEMSQTITDLLNEQKVSTSQASPQSAASPRIESTTGITTTTSPKTPPPLTVQDTLCPAVCPLEELSPDSIDAHTFDFETISHPNTEQPVHQASIDLDSLAESPESDFMSAVNEFVIEENLSSPNPISDPQSPEMMVESLYSSVINAIDSRRMQDTSTRGNEGFGDRAALHVQLEKCRAAAQDSHSSIQTIKDDLCHFRTFVQKEQCDLANYLKCTAVEIRNIIEKVKCSLEITLKEKHQQELQSLKIEYECKLDALVKDSEENVNKILKLKENLVSLEEALQNKDNEFTSIKHEKDAIVCVQQEKDQKLLEMEKIMHTQHCEIKELKQSREMALEDLKKLH---DEKIESLRAEFQCLEQNHLKELEDTLHIRHTQEFEKVMTDHNMSLEKLKKENQQRIDQMLESHASTIQEK-EQQLQELKLKVSDLSDMRCKLEVELALKEAETDEIKILLEESRTQQKEMLKSLLEQETENLRTEISKLNQKIHDNNESYQVGLSELRALMTIEKDQCISELISRHEEESNILKAELDNVTSLHRQAYEIEKKLKEQIVELQTRLNSELSALEKQKDEKITQQEEKYEALIQNLEKDKERLVKNHEQDKEHLIQELNFEKNKAVQTALDEFKVERELVEKELLEKVKHLENQIAKTPAFESAREDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFNTVLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSEDRARLLEEKKQLEEEVSKLRTSSFLSSAPVAAAPELYGACAPELPGEPERSVMETADEGRLDSAMETSMMSVQEN--MLSEEKQRIMLLERTLQLKEEENKRLNQRLMSQSLSSVSSRHSEKIAIRDFQVGDLVLIILDERHDNYVLFTVSPTLYFLHSESLPALDLKPGEGASGASRRPWVLGKVMEKEYCQAKKAQNRFKVPLGTKFYRVKAVSWNKKV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TDY2-1", "uniprot_id": "RBCC1_HUMAN", "id": "Q8TDY2-1", "name": "RB1-inducible coiled-coil protein 1", "aln": "MKLYVFLVNTGTTLTFDTELTVQTVADLKHAIQSKYKIAIQHQVLVVNGGECMAADRRVCTYSAGTDTNPIFLFNKEMILCDRPPAIPKTTFSTENDMEIKVEESLMMPAVFHTVASRTQLALEMYEVAKKLCSFCEGLVHDEHLQHQGWAAIMANLEDCSNSYQKLLFKFESIYSNYLQSIEDIKLKLTHLGTAVSVMAKIPLLECLTRHSYRECLGRLDSLPEHEDSEKAEMKRSTELVLSPDMPRTTNESLLTSFPKSVEHVSPDTADAESGKEIRESCQSTVHQQDETTIDTKDGDLPFFNVSLLDWINVQDRPNDVESLVRKCFDSMSRLDPRIIRPFIAECRQTIAKLDNQNMKAIKGLEDRLYALDQMIASCGRLVNEQKELAQGFLANQKRAENLKDASVLPDLCLSHANQLMIMLQNHRKLLDIKQKCTTAKQELANNLHVRLKWCCFVMLHADQDGEKLQALLRLVIELLERVKIVEALSTVPQMYCLAVVEVVRRKMFIKHYREWAGALVKDGKRLYEAEKSKRESFGKLFRKSFLRNRLFRGLDSWPPSFCTQKPRKFDCELPDISLKDLQFLQSFCPSEVQPFLRVPLLCDFEPLHQHVLALHNLVKAAQSLDEMSQTITDLLSEQKASVSQTSPQSASSPRMESTAGITTTTSPRTPPPLTVQDPLCPAVCPLEELSPDSIDAHTFDFETIPHPNIEQTIHQVSLDLDSLAESPESDFMSAVNEFVIEENLSSPNPISDPQSPEMMVESLYSSVINAIDSRRMQDTNVCGKEDFGDHTSLNVQLERCRVVAQDSHFSIQTIKEDLCHFRTFVQKEQCDFSNSLKCTAVEIRNIIEKVKCSLEITLKEKHQKELLSLKNEYEGKLDGLIKETEENENKIKKLKGELVCLEEVLQNKDNEFALVKHEKEAVICLQNEKDQKLLEMENIMHSQNCEIKELKQSREIVLEDLKKLHVENDEKLQLLRAELQSLEQSHLKELEDTLQVRHIQEFEKVMTDHRVSLEELKKENQQIINQIQESHAEIIQEK-EKQLQELKLKVSDLSDTRCKLEVELALKEAETDEIKILLEESRAQQKETLKSLLEQETENLRTEISKLNQKIQDNNENYQVGLAELRTLMTIEKDQCISELISRHEEESNILKAELNKVTSLHNQAFEIEKNLKEQIIELQSKLDSELSALERQKDEKITQQEEKYEAIIQNLEKDRQKLVSSQEQDREQLIQKLNCEKDEAIQTALKEFKLEREVVEKELLEKVKHLENQIAKSPAIDSTRGDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFNTVLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSEDRARLLEEKKKLEEEVSKLRSSSFVPSPYVATAPELYGACAPELPGESDRSAVETADEGRVDSAMETSMMSVQENIHMLSEEKQRIMLLERTLQLKEEENKRLNQRLMSQSMSSVSSRHSEKIAIRDFQVGDLVLIILDERHDNYVLFTVSPTLYFLHSESLPALDLKPGEGASGASRRPWVLGKVMEKEYCQAKKAQNRFKVPLGTKFYRVKAVSWNKKV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7KTS2-1", "uniprot_id": "Q7KTS2_DROME", "id": "Q7KTS2-1", "name": "RB1-inducible coiled-coil protein 1", "aln": "MMLYVFHVDVGRMLSFDMNVALQPVEHLKETIQKLHNIPAANIVLLVSGGEMLTHSTQVSCYSAGTDTNPIYMF----LTGDERLPPTIYNSDADNELRRQVEESHRLPPALETVRQRAQLAQHMRELARKEEDQCERLVHEQHLQQQGWSAVVANMEDLTNEFCDRFQNFCSFFDRHLQKRESFLELLRNFPDDLKQLGRIPILPDLMSLAEADFHG-FDELLDNDDVFTAQQQPTPQQQALTESSQADSPNKKLKMGDEVETESGE--QTERGVQTLTSSSSLARR---------------PNLNLLQWISSKGNHRALQLMSDECIQGLDVFSVEIYEKLKEEVNQIIKLANQADVKEIKGLGDRLCKLEEFKFRIKKMVQEQKEQALALQQNEARAQNLRDNSVLPDLCLSHRSQLQVMLDNHIKIREYCRCIANSKDELGWNLHTRLRRIVWIENGMSEFDNRLLFNHRCLRRAERHICIIEQIHRAPSTYVSAVAEVVRRKIFSDEFRQWATRLSADFDRIHSEELSRRRDFNASFEGHFLN-ILFPGMGDMPPAFANEHPLSFDTRLPSLSRSDMELLSSQLPELAG---QLQLPDMKPVIDFFALRSDKNVEPDQEQERDIPLMAPRLAELQAQAAASDCETDTETEFEKLSTTSKCVATSISTSLVEQVAQSTATEDLLMLSAG-----------------------------TLTEENAGSFEKMRSDMESMTKLAR-ACLAEARSNVGVFRSDVANYQDELQS------------------ELHLLRDKCNVLKMMCEEREQKLQEKLDEMSLKLQLAEQEKQ---------------AAVAQAREQLIHEHKTELESLRCRFKLMTSMERSPSDSSLEKIERPTSSASVVSANAG---------------------------VDIDHLLAQQR---QELLAQRERAISEAVDSE--------------RSLWQSRLLPLNSESVMANVGILKDMLADKERQLDQLREQNKILTQETYQLKTRLEMITNEDGNSWLKEKIDYLNKDKCRLEEELSQEKSRRQEMESSVAAMRS---------------------SAYDLNVGGPLTRSKSGVSSSHRSIALEGCARGDLVFVVWSMRHAQFMVVQDSLTLYFVHADSLAS------LQLTAPTSPTPSLDPSQTVVDINQIPLPYYAIGRVIDKEYCQARKDDNRYR--------------VSRGSKFYRIKLAPLPSRNASRRERLESSSSIAAVVASPRD------------------------------------------VIDAPSSNTSVYQSFKQRTVSITSVNEEDDESASLLSERCRYISVSEEDELHAAGGSMPAVTAAVATGTSTAASSATPITTAAPVAGGPTSTAPTAATQAQSVITEQPTASSKLKLDLLLASAD-----------IITQPLTQQPHQQRQELDQPAEAESTAPVAETSPNQTIQPEDPDPEPETITIYVPPNAPAVLTATPSTRASILASISAKPIISTDSMLPMS----IGTAAISEDSDEYRSLEGKDDGDGDADDFPISE-------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* **** *:.* *:** ::::*.* .**.:**. ::*. : **:*.*** :: . :*. **********::* : *. . . . .::*::. :**** :*..:.** .*:*** .* ::*:* . ** ***::***:***:*::**:** :..: . : :* *::. :**. *.: * :: :. :.:**:* * : : * *.* :::. .*: : :.: .: .:: . . .: ..:* : : :* * : *..* .:: *:.**:**. :.. . :: : :*::.:. :. .* . : * .* * :: ::* **** *** *::: ::*:**** * .: *: **:**:* ********** .** :**:** *: : : :.:*:**. ***.**: :: .: .::* * : . .:: *:* : .*. * **.******:* ..:*:** * * .:::. * *:*..*. *. **. ** *:.. *.:*..::* .** .**.:* .*:::*.* *. . :: * :. ..* .: *:. *. :. :: * * :...: :. :: :...:*. : :. .:. ...*. * . .*. * **.. :*:*. ..* . .:: :*: :::.:* :..* :. : ::* *:: ::*.. .. *.:::.* .: :* : : . .. . * .:*: ** **: .:: . . ::.. :** : . . :. ::::::: *. :** .** .:.: . . :.* *.:* *:. : : ::.:::*:. .*::*:::*: :: : :: . *. . ** *:. *.. :*:** **: :::. :*:: : *: . : :: . : *::. : :::* . :: . . : . :.:* . :* .: . ::* : .. * *. .*.* * *: : ::*: : ..:: : :. . . :::: : .. .: ::**.. : :... *.* : : :. .:* * *. .* . .:. :*: .** : : * .:: . : *:. ::: .:. : :*. : *. :. * . :: ::: .* :: .:: .. : :: : * .::.:.*:* ::* :.*:. .:: : : * : : .::*.:*: *:.* : . :. * : .:.:: : :. :.: . .:. : :. ", "identical_positions": 282, "similar_positions": 565, "identity": "17.68%" }, { "cls_id": "homologset.agr.RGD:1309349", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9H2X6-1", "uniprot_id": "HIPK2_HUMAN", "id": "Q9H2X6-1", "name": "Homeodomain-interacting protein kinase 2", "aln": "MAPVYEGMASHVQVFSPHTLQSSAFCSVKKLKIEPSSNWDMTGYGSHSKVYSQSKNIPLSQPATTTVSTSLPVPNPSLPYEQTIVFPGSTGHIVVTSASSTSVTGQVLGGPHNLMRRSTVSLLDTYQKCGLKRKSEEIENTSSVQIIEEHPPMIQNNASGATVATATTSTATSKNSGSNSEGDYQLVQHEVLCSMTNTYEVLEFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQIEVSILARLSTESADDYNFVRAYECFQHKNHTCLVFEMLEQNLYDFLKQNKFSPLPLKYIRPVLQQVATALMKLKSLGLIHADLKPENIMLVDPSRQPYRVKVIDFGSASHVSKAVCSTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGASEYDQIRYISQTQGLPAEYLLSAGTKTTRFFNRDTDSPYPLWRLKTPDDHEAETGIKSKEARKYIFNCLDDMAQVNMTTDLEGSDMLVEKADRREFIDLLKKMLTIDADKRITPIETLNHPFVTMTHLLDFPHSTHVKSCFQNMEICKRRVNMYDTVNQSKTPFITHVAPSTSTNLTMTFNNQLTTVHNQAPSSTSATISLANPEVSILNYPSTLYQPSAASMAAVAQRSMPLQTGTAQICARPDPFQQALIVCPPGFQGLQASPSKHAGYSVRMENAVPIVTQAPGAQPLQIQPGLLAQQAWPSGTQQILLPPAWQQLTGVATHTSVQHATVIPETMAGTQQLADWRNTHAHGSHYNPIMQQPALLTGHVTLPAAQPLNVGVAHVMRQQPTSTTSSRKSKQHQSSVRNVSTCEVSSSQAISSPQRSKRVKENTPPRCAMVHSSPACSTSVTCGWGDVASSTTRERQRQTIVIPDTPSPTVSVITISSDTDEEEEQKHAPTSTVSKQRKNVISCVTVHDSPYSDSSSNTSPYSVQQRAGHNNANAFDTKGSLENHCTGNPRTIIVPPLKTQASEVLVECDSLVP-VNTSHHSSSYKSKSSSNVTSTSGHSSGSSSGAITYRQQRPGPHFQQQQPLNLSQAQQHITTDRTGSHRRQQAYITPTMAQAPYSFPHNSPSHGTVHPHLAAAAAAAHLPTQPHLYTYTAPAALGSTGTVAHLVASQGSARHTVQHTAYPASIVHQVPVSMGPRVLPSPTIHPSQYPAQFAHQTYISASPASTVYTGYPLSPAKVNQYP-----YI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0M8N4-1", "uniprot_id": "A0ABK0M8N4_RAT", "id": "A0ABK0M8N4-1", "name": "non-specific serine/threonine protein kinase", "aln": "MAPVYEGMASHVQVFSPHTLQSSAFCSVKKLKVEPSSNWDMTGYGSHSKVYSQSKNIPPSQPASTTVSTSLPIPNPSLPYEQTIIFPGSTGHIVVTSASSTSVTGQVLGGPHNLMRRSTVSLLDTYQKCGLKRKSEEIENTSSVQIIEEHPPMIQNNASGATVATATTSTATSKNSGSNSEGDYQLVQHEVLCSMTNTYEVLEFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQIEVSILARLSTESADDYNFVRAYECFQHKNHTCLVFEMLEQNLYDFLKQNKFSPLPLKYIRPVLQQVATALMKLKSLGLIHADLKPENIMLVDPSRQPYRVKVIDFGSASHVSKAVCSTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGASEYDQIRYISQTQGLPAEYLLSAGTKTTRFFNRDTDSPYPLWRLKTPDDHEAETGIKSKEARKYIFNCLDDMAQVNMTTDLEGSDMLVEKADRREFIDLLKKMLTIDADKRITPIETLNHPFVTMTHLLDFPHSTHVKSCFQNMEICKRRVNMYDTVNQSKTPFITHVAPSTSTNLTMTFNNQLTTVHNQAPTSTSATLSLANPEVSILNYQSTLYQPSAASMAAVAQRSMPLQTGTAQICARPDPFQQALIVCPPGFQGLQASPSKHAGYSVRMENAVPIVTQAPGAQPLQIQPGLLAQQAWPGGAQQILLPPAWQQLTGVATHTSVQHAAVIPETMAGTQQLADWRNTHAHGSHYNPIMQQPALLTGHVTLPAAQPLNVGVAHVMRQQPTSTTSSRKSKQHQSSARNVSTCEVTSSQAISSPQRSKRVKENTPPRCAMVHSSPACSTSLTCGWGDGASSTTRDRQRQTIVIPDTPSPTVSVITISSDTDEEEEQKHAPTSTVSKQRKNVISCVTVHDSPYSDSSSNTSPYSVQQRTGHNGTNTLDTKGGLENHCTGNPRTIIVPPLKTQASEVLVECDSLGPAISTGHHSSSFKSKSSSTVTSTSGHSSGSSSGAIAYRQQRPGPHFQQQQPLNLSQAQQHMAADRTGSHRRQQAYITPTMAQAPYTFPHSSPSHGTVHPHLAAAA---HLPAQPHLYTYTAPTALGSTSTVAHLVASQGSARHTVQHTAYPASIVHQVPVSMGPRVLPSPTIHPSQYPAQFAHQTYISASPASTVYTGYPLSPAKFRMASKEHLHYV", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "********************************:************************* ****:********:***********:*******************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************:*****:************ ********************************************************************************************.*:************************:**************************************************************************.********:**********************************:****** ******:************************************************************************:***.:*::****.******************************* * :.*.*****:******.****************:************************:::**********************:***.*************** ***:**********:*****.****************************************************************************.. . *:", "identical_positions": 1152, "similar_positions": 37, "identity": "95.68%" }, { "cls_id": "homologset.agr.RGD:1309350", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZCS9-1", "uniprot_id": "D3ZCS9_RAT", "id": "D3ZCS9-1", "name": "5-hydroxyisourate hydrolase", "aln": "MSSRTAPRLMTLQRHLGGPQAGN--MATESSPLTTHVLDTASGLPAQGLCLRLCRLEAPSQQWMELRTSYTNLDGRCPGLLTQSQMKPGTYKLSFDTERYWKERGQESFYPYVEVVFTITKETQKFHVPLLLSPWSYTTYRGS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CRB3-1", "uniprot_id": "HIUH_MOUSE", "id": "Q9CRB3-1", "name": "5-hydroxyisourate hydrolase", "aln": "-------------------------MATESSPLTTHVLDTASGLPAQGLCLRLSRLEAPCQQWMELRTSYTNLDGRCPGLLTPSQIKPGTYKLFFDTERYWKERGQESFYPYVEVVFTITKETQKFHVPLLLSPWSYTTYRGS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q06S87-1", "uniprot_id": "HIUH_DANRE", "id": "Q06S87-1", "name": "5-hydroxyisourate hydrolase", "aln": "MN-----RLQHIRGHIVSADKHINMSATLLSPLSTHVLNIAQGVPGANMTIVLHRLDPVSSAWNILTTGITNDDGRCPGLITKENFIAGVYKMRFETGKYWDALGETCFYPYVEIVFTITNTSQHYHVPLLLSRFSYSTYRGS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z8C9-1", "uniprot_id": "A1Z8C9_DROME", "id": "A1Z8C9-1", "name": "5-hydroxyisourate hydrolase", "aln": "---------------------------MDARKFSTHILDTSVGKAAANVRVTVSRLDEI-QEWRSLRAAQTDADGRCL-LLEPGQFPGGIYKLTFHVGAYYAERNVRTLYPAIDLIVDCS-ENQNYHIPLLLNPFGYSTYRGT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::**:*: : * .. .: : : **: . * * :. *: **** *: :: * **: *.. *: . :** ::::. : .*::*:****. :.*:****:", "identical_positions": 32, "similar_positions": 40, "identity": "22.38%" }, { "cls_id": "homologset.agr.RGD:1309353", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZD31-1", "uniprot_id": "D3ZD31_RAT", "id": "D3ZD31-1", "name": "Macrophage mannose receptor 1", "aln": "MEHTLWAMRLPLLLAFISVIPVAVQLLDSRQFLIYNEDHKRCVDALSAISVQTATCNPEAESQKFRWVSESQIMSVAFKLCLGVPSKTDWASVTLYACDSKSEFQKWECKNDTLFGIKGTELYFNYGNRQEKNIKLYKGSGLWSRWKVYGTTDDLCSRGYEAMYSLLGNANGAVCAFPFKFENKWYADCTSAGRSDGWLWCGTTTDYDTDKLFGFCPLQFEGSKRLWNTDPLTGILYQINSKSALTWHQARASCKQQNAELLSVTEIHEQMYLTGLTSSLTSGLWIGLNSLSLSTGWQWAGGSPFRYLNWLPGSPSSEPGKSCVSLNPGKNAKWENLECVQKLGYICKKGNNTLNPFIIPSESDVPTACPNQWWPYAGHCYRIYREEKKIQKYALQACRKEGGDLASIHSIEEFDFIFSQLGYEPNDELWIGLNDIKIQMYFEWSDGTPVTFTKWLPGEPSHENNRQEDCVVMKGKDGYWADRACEQPLGYICKMVSQIHTVI--PEGAEKGCRKGWKRHGFYCYLIGSTLSTFADANQTCTNEKAYLTTVEDRYEQAFLTSLVGLRPEKYFWTGLSDVQNKGTFRWTVDEQVQFTHWNADMPGRKAGCVAMKTGVAGGLWDVLSCEEKAKFVCKHWAEGVTRPPEPTTTPEPKCPEDWGTTSKTSMCFKLYAKGKHEKKTWFESRDFCKAIGGELASIKSKDEQQVIWRLITSSGSYHELFWLGLTYGSPSEGFTWSDGSPVSYENWAYGEPNNYQNVEYCGELKG---DPGMSWNDINCEHLNNWICQIQKGKTLLPEPTPAPQDNPPVTADGWVIYKDYQYYFSK-EKETMDNARAFCKKNFGDLATIKSESEKKFLWKYINKNGGQSPYFIGLLISLDKKFIWMDGSKVDFVAWATGEPNFANDDENCVTMYTNSGFWNDINCGYPNNFICQRHNSS-INAT-AMPTTPPTPGGCKEGWHLYNNKCFKIFGFAEEEKKTWKEARKACIGLKGNLVSIENAKEQAFVTYHMRDSTFNAWTGLNDVNSEHTFLWTDGRGVHYTNWGKGYPGGRRSSLSY-----EDVDCVVVIGGNSREAGTWMDSTCDSKQGYICQTQTDPSVPISPTTAPKDGFVKYGKSSYALMKLKSPWHEAEKYCKDRTSLLASILDPYSNAFAWMKMHPFNVPIWIALNSNLTNNEYTWTDKWRVRYTNWGTDEPKLKSACVYMDVDGYWKTSYCNESFYFLCKKSDEIPATEPPQLPGKCPESE---QTAWIPFHGHCYYIESSFTRSWGQASLECLRMGASLVSIETAAESSFLSYRVEPLKSKTNFWIGMFRNVEGKWLWLNDNPVSFVNWKTGDPSGE------RNDCVVLSSSSGLWNNIHCT-SYKGFICKMPKIIDPVTTHSSITTKADQRKMDPQPKGSSKAAGVVIVVLLIVIGAGVAAYFFYKKRRVLHIPQEATFENTLYFNSNPSPGTSDTKDLVGNIEQNEHAVI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61830-1", "uniprot_id": "MRC1_MOUSE", "id": "Q61830-1", "name": "Macrophage mannose receptor 1", "aln": "-------MRLLLLLAFISVIPVSVQLLDARQFLIYNEDHKRCVDALSAISVQTATCNPEAESQKFRWVSDSQIMSVAFKLCLGVPSKTDWASVTLYACDSKSEYQKWECKNDTLFGIKGTELYFNYGNRQEKNIKLYKGSGLWSRWKVYGTTDDLCSRGYEAMYSLLGNANGAVCAFPFKFENKWYADCTSAGRSDGWLWCGTTTDYDKDKLFGFCPLHFEGSERLWNKDPLTGILYQINSKSALTWHQARASCKQQNADLLSVTEIHEQMYLTGLTSSLSSGLWIGLNSLSVRSGWQWAGGSPFRYLNWLPGSPSSEPGKSCVSLNPGKNAKWENLECVQKLGYICKKGNNTLNPFIIPSASDVPTGCPNQWWPYAGHCYRIHREEKKIQKYALQACRKEGGDLASIHSIEEFDFIFSQLGYEPNDELWIGLNDIKIQMYFEWSDGTPVTFTKWLPGEPSHENNRQEDCVVMKGKDGYWADRACEQPLGYICKMVSQSHAVV--PEGADKGCRKGWKRHGFYCYLIGSTLSTFTDANHTCTNEKAYLTTVEDRYEQAFLTSLVGLRPEKYFWTGLSDVQNKGTFRWTVDEQVQFTHWNADMPGRKAGCVAMKTGVAGGLWDVLSCEEKAKFVCKHWAEGVTRPPEPTTTPEPKCPENWGTTSKTSMCFKLYAKGKHEKKTWFESRDFCKAIGGELASIKSKDEQQVIWRLITSSGSYHELFWLGLTYGSPSEGFTWSDGSPVSYENWAYGEPNNYQNVEYCGELKG---DPGMSWNDINCEHLNNWICQIQKGKTLLPEPTPAPQDNPPVTADGWVIYKDYQYYFSK-EKETMDNARAFCKKNFGDLATIKSESEKKFLWKYINKNGGQSPYFIGMLISMDKKFIWMDGSKVDFVAWATGEPNFANDDENCVTMYTNSGFWNDINCGYPNNFICQRHNSS-INAT-AMPTTPTTPGGCKEGWHLYKNKCFKIFGFANEEKKSWQDARQACKGLKGNLVSIENAQEQAFVTYHMRDSTFNAWTGLNDINAEHMFLWTAGQGVHYTNWGKGYPGGRRSSLSY-----EDADCVVVIGGNSREAGTWMDDTCDSKQGYICQTQTDPSLPVSPTTTPKDGFVTYGKSSYSLMKLKLPWHEAETYCKDHTSLLASILDPYSNAFAWMKMHPFNVPIWIALNSNLTNNEYTWTDRWRVRYTNWGADEPKLKSACVYMDVDGYWRTSYCNESFYFLCKKSDEIPATEPPQLPGKCPESE---QTAWIPFYGHCYYFESSFTRSWGQASLECLRMGASLVSIETAAESSFLSYRVEPLKSKTNFWIGMFRNVEGKWLWLNDNPVSFVNWKTGDPSGE------RNDCVVLASSSGLWNNIHCS-SYKGFICKMPKIIDPVTTHSSITTKADQRKMDPQPKGSSKAAGVVTVVLLIVIGAGVAAYFFYKKRHALHIPQEATFENTLYFNSNLSPGTSDTKDLMGNIEQNEHAII", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P22897-1", "uniprot_id": "MRC1_HUMAN", "id": "P22897-1", "name": "Macrophage mannose receptor 1", "aln": "-------MRLPLLLVFASVIPGAVLLLDTRQFLIYNEDHKRCVDAVSPSAVQTAACNQDAESQKFRWVSESQIMSVAFKLCLGVPSKTDWVAITLYACDSKSEFQKWECKNDTLLGIKGEDLFFNYGNRQEKNIMLYKGSGLWSRWKIYGTTDNLCSRGYEAMYTLLGNANGATCAFPFKFENKWYADCTSAGRSDGWLWCGTTTDYDTDKLFGYCPLKFEGSESLWNKDPLTSVSYQINSKSALTWHQARKSCQQQNAELLSITEIHEQTYLTGLTSSLTSGLWIGLNSLSFNSGWQWSDRSPFRYLNWLPGSPSAEPGKSCVSLNPGKNAKWENLECVQKLGYICKKGNTTLNSFVIPSESDVPTHCPSQWWPYAGHCYKIHRDEKKIQRDALTTCRKEGGDLTSIHTIEELDFIISQLGYEPNDELWIGLNDIKIQMYFEWSDGTPVTFTKWLRGEPSHENNRQEDCVVMKGKDGYWADRGCEWPLGYICKMKSRSQGPE--IVEVEKGCRKGWKKHHFYCYMIGHTLSTFAEANQTCNNENAYLTTIEDRYEQAFLTSFVGLRPEKYFWTGLSDIQTKGTFQWTIEEEVRFTHWNSDMPGRKPGCVAMRTGIAGGLWDVLKCDEKAKFVCKHWAEGVTHPPKPTTTPEPKCPEDWGASSRTSLCFKLYAKGKHEKKTWFESRDFCRALGGDLASINNKEEQQTIWRLITASGSYHKLFWLGLTYGSPSEGFTWSDGSPVSYENWAYGEPNNYQNVEYCGELKG---DPTMSWNDINCEHLNNWICQIQKGQTPKPEPTPAPQDNPPVTEDGWVIYKDYQYYFSK-EKETMDNARAFCKRNFGDLVSIQSESEKKFLWKYVNRNDAQSAYFIGLLISLDKKFAWMDGSKVDYVSWATGEPNFANEDENCVTMYSNSGFWNDINCGYPNAFICQRHNSS-INATTVMPTMPSVPSGCKEGWNFYSNKCFKIFGFMEEERKNWQEARKACIGFGGNLVSIQNEKEQAFLTYHMKDSTFSAWTGLNDVNSEHTFLWTDGRGVHYTNWGKGYPGGRRSSLSY-----EDADCVVIIGGASNEAGKWMDDTCDSKRGYICQTRSDPSLTNPPATIQTDGFVKYGKSSYSLMRQKFQWHEAETYCKLHNSLIASILDPYSNAFAWLQMETSNERVWIALNSNLTDNQYTWTDKWRVRYTNWAADEPKLKSACVYLDLDGYWKTAHCNESFYFLCKRSDEIPATEPPQLPGRCPESD---HTAWIPFHGHCYYIESSYTRNWGQASLECLRMGSSLVSIESAAESSFLSYRVEPLKSKTNFWIGLFRNVEGTWLWINNSPVSFVNWNTGDPSGE------RNDCVALHASSGFWSNIHCS-SYKGYICKRPKIIDAKPTHELLTTKADTRKMDPSKPSSNVAGVVIIVILLILTGAGLAAYFFYKKR-RVHLPQEGAFENTLYFNSQSSPGTSDMKDLVGNIEQNEHSVI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13AB58-1", "uniprot_id": "A0AB13AB58_DANRE", "id": "A0AB13AB58-1", "name": "", "aln": "-------MKIITVVVLLVLELSNCFAQSGDSFLLYNVDSNKCLTST---LNRLVTCDPHSAQQKFRWTSSNRILNTFTKTCLGVGSKTVGKTLQPLKCNDDNALQKWECHGNTLLGLKNETLFLAVDFRGLP--EISNKTGIRSKWTIHGTQDSICSRPYEEIYSIDGNGFGQTCKFPFLYEKKWYADCTTVDEPDQRLWCATKTDYSLYEQWGYCPTRDS---KYWTKHPLTNVYYQLNDRSTLTWYQARKSCQQQGAELLSISEPHEQSFIAGMFQKSQGSLWIGLNKLDVSSGWQWSNGQPLRYLKWLSGFPSSQPGYNCGVLKNGYNSEWSNDACSEKRGYICQRGHSVP---TVPPEVTTG-FCQSPWIPHSGNCYLLHR-TKQTWLEARDICLREGGDLLSILSTEEQSFAITQLGYSKTDQLWIGFNDRKTQMLFEWSDQSSVPFASWEVGEPTHSAQHAEDCVLMRGEEGKWADDVCEKKYGFICKRKTSTKASNNDTVVTNPGCKKGWIRYGYYCYMAGSETKTFEEAKQTCEKAESRLVDVSSRVENAFLVNLVGARPEKYFWIGLSNQKDVHTFEWTNTKQVPFTHFNSGMPGRKQGCVAMTTGIVAGLWDVLSCSNKEKYICKQRADALVTTAAPPTTPSLDCPTEWTSIGTRDLCVKHFNVPSLQMKTWDQALDYCRELGGDLLSIHH--ESDIPWK---QGGGYPS--WIGYRMYDPSVGYVWSDGSSSSYQSWASDEPNNLNNMENCVEMRVSLWDDDGMWNDVNCKDKKDWYCQIHKGKTPVEVNITEPVYN--VTEDGWIEFRGSQYYGSEYSAMSMHEARAFCKRNHGDLVVINDEEERLFLWHKSKE--LYNDFLIGLTVDLDGSFQWMDGSPVVFQAWEANQPAFKNSEERCAKMTISQGLWETVNCGDEYNYFCKRSEAPPVNAT-VAPTQPPK-GGCAPEWTQFEGKCYNVRG----EMKKWSEAREYCREHGGDLTAIMSKFQQTFLSTMIRDKSTNFWIGFSNL-ANGRFKWTDGSKVSFTEWAEGEPHSLSRSYYWTKYFSDEPECVFMGRSSGSHFSKWVADDCNSTNGFICSRDVDPGIPSVPTEIPKT-FVKLGNSSFKVIQENLTWIEANRRCKAEGGHLASIRDLISQAYIELQVFRLKQPMWIGLNSEQSNGYFLWVNKWPMTMEKWAIAEPRPNKPCAHMKINGEWKTSLCNETFYSVCEQTTDIPPTLPAQQPGHCPKQENYSPLRWIPFRDSCYAFVTEMK-SWSRAARLCMTWGASLASIRDEAEEKFIESNLLLLESYKEFWIGLLHNHKGHWLWADNSVVDYTNWALTETDGDYEEFSYNPDCAFISATSKNWKKRHCDYTVLPFICKTAKVMSP-------TIKSPHQDIKPHRVKTGLAVFLTIAVIAILG---ALAYVYYRRSQHRFLP---TFENPMYNNAESAYSDKDNKSLLEVAE-------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:: ::.: : . .**:** * ::*: : : .:*: .: .*****.*..:*:.. * **** *** :: *:... *****:.:**:*:*. *:: . * : : :*: *:*.::** *.:*** ** :*:: **. * .* *** :*:*******:....* ***.*.***. : :*:** : . *...***.: **:*.:*:***:*** **:**.*:***::* *** :::*: .. ..******.*.. :****:. .*:***:**.* **::** .* *: * *::*.* * :* ****::*:.. :*. . * . * *::*:** ::* *: * * :***** ** : ** .* ::****. .*:****:** * ** ***** :.*.*:.* ***:*. :: ****:*:*::* *** ** *:*** : : .: **:*** :: :***: * .** :*::** : :: *. :..* *:***..:** ******* ***: : **.** ::* ***:*:.***** ***** **:..******.*.:* *::**: *:.:. .. *.***. .** :* : . .:*.* : . : *** :: *:*: :**:* **: *.: *: .*.* . *:* .** *:.*****. **:.** .**** :*:* * *:: * ***:**:. ::* ***:**:* . * * ** ***: ::. *** *: . :*.:******:*.***. *:.*.*: ***: :. . ::**: :.:* .* ***** * : :* :.:* * *.:*.*..* ..*:*: :*** ::*:* ::. :*** . ** *. .** * :..**::: * * *.*.:**: * *:*.:* . :*:*:: ::*.: . * *:.:: :: * ** * * :*:*.:* * . * : :: :**.: . . . ..*: . *:*..*:**. **.:. *: . **. *:**: ::: : * **: ** . . :*** * *:*: ::: : :**.***: ::. : *.::* : :*. **: :..*.::.::* *:*: ***:** :*::: :**.* *.* **:**:.: **** . ** : :. . .*.:*: *: *:**.**. **..*:. .: *:* .:****:::* :* *** ::. *.:.** :..*: . **. : ::* *.: ** : :*** .*::.. * *: :.:.* :. * : .:: *: **.:*:: .:* :***.:* *:: : . .* *.*: * ", "identical_positions": 525, "similar_positions": 485, "identity": "35.33%" }, { "cls_id": "homologset.agr.RGD:1309355", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XIA1-1", "uniprot_id": "NCLN_RAT", "id": "Q5XIA1-1", "name": "BOS complex subunit NCLN", "aln": "MLEEAGEVLENVLKASCLPLGFIVFLPAVLLLVAPPLPAADAAHEFTVYRMQQYDLQGQPYGTRNAVLNTEARTVDADVLSRRCVLMRLLDFSYEHYQKALRQSAGAVVIILPRAMAAVPQDVVRQFMEIEPEMLAMETVVPVYFAVEDEALLSIYEQTQAASASQ--GSASAAEVLLHTATANGFQMVTSGAQSQAVSDWLITSVEGRLTG-----------LGGEDLPTIVIVAHYDAFGVAPWLSLGADSNGSGISVLLELARLFSRLYTYKRTHAAYNLLFFASGGGKFN-YQGTKRWLEDSLDHTDSSLLQDNVAFVLCLDTVGR------GSHLRLHVSKPPREGTLQHVFLRELEMVAAHQFPDVSFSMVHKKINLADDVLAWEHERFAIRRLPAFTLSHLENHRAGPRSSIMDVRSR---------------VDSKTLTRNTRIIAEALTRVIYNLTEKGTPPDMPVFTEQMQVQQEQIDSVMDWLTNQPRAAQLLDKDGTFLSTLEHFLSRYLKDVRQHHVKADKRDPEFVFYDQLKQVMNAYRVKPAIFDLLLALCIGAYLGMAYTAVQHFHVLYKTVQRLLLKAKAQ---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VCM8-1", "uniprot_id": "NCLN_MOUSE", "id": "Q8VCM8-1", "name": "BOS complex subunit NCLN", "aln": "MLEEAGEVLENVLKASCLPLGFIVFLPAVLLLVAPPLPAADAAHEFTVYRMQQYDLQGQPYGTRNAVLNTEARTVDADVLSRRCVLMRLLDFSYEHYQKALRQSAGAVVIILPRAMAAVPQDVVRQFMEIEPEMLAMETVVPVYFAVEDEALLSIYEQTQAASASQ--GSASAAEVLLHTATANGFQMVTSGAQSQAVSDWLITSVEGRLTG-----------LGGEDLPTIVIVAHYDAFGVAPWLSLGADSNGSGISVLLELARLFSRLYTYKRTHAAYNLLFFASGGGKFN-YQGTKRWLEDSLDHTDSSLLQDNVAFVLCLDTVGR------GSHLRLHVSKPPREGTLQHAFLRELETVAAHQFPDVSFSMVHKKINLADDVLAWEHERFAIRRLPAFTLSHLESHRAGPRSSIMDVRSR---------------VDSKTLTRNTRIIAEALTRVIYNLTEKGTPPDMPVFTEQMQVQEEQIDSVMDWLTNQPRAAQLLDKDGTFLSTLEHFLSRYLKDVRQHHVKADKRDPEFVFYDQLKQVMNAYRVKPAIFDLLLALCIGAYLGMAYTAVQHFHVLYKTVQRLLLKAKAQ---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q969V3-1", "uniprot_id": "NCLN_HUMAN", "id": "Q969V3-1", "name": "BOS complex subunit NCLN", "aln": "MLEEAGEVLENMLKASCLPLGFIVFLPAVLLLVAPPLPAADAAHEFTVYRMQQYDLQGQPYGTRNAVLNTEARTMAAEVLSRRCVLMRLLDFSYEQYQKALRQSAGAVVIILPRAMAAVPQDVVRQFMEIEPEMLAMETAVPVYFAVEDEALLSIYKQTQAASASQ--GSASAAEVLLRTATANGFQMVTSGVQSKAVSDWLIASVEGRLTG-----------LGGEDLPTIVIVAHYDAFGVAPWLSLGADSNGSGVSVLLELARLFSRLYTYKRTHAAYNLLFFASGGGKFN-YQGTKRWLEDNLDHTDSSLLQDNVAFVLCLDTVGR------GSSLHLHVSKPPREGTLQHAFLRELETVAAHQFPEVRFSMVHKRINLAEDVLAWEHERFAIRRLPAFTLSHLESHRDGQRSSIMDVRSR---------------VDSKTLTRNTRIIAEALTRVIYNLTEKGTPPDMPVFTEQMQIQQEQLDSVMDWLTNQPRAAQLVDKDSTFLSTLEHHLSRYLKDVKQHHVKADKRDPEFVFYDQLKQVMNAYRVKPAVFDLLLAVGIAAYLGMAYVAVQHFSLLYKTVQRLLVKAKTQ---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NZ07-1", "uniprot_id": "NCLN_DANRE", "id": "Q6NZ07-1", "name": "BOS complex subunit ncln", "aln": "MFEEAGEVLENMLKVS-FPLSLVLFL----VLVCP--LRAEAAHEFSVYRMQQYDLQGQTYGSRNAILNTEARTVEAEVLSRRCVMMRLADFSYEKYQKALRQSAGAVVIILPHNMSTLPQDIVQQFMELEPELLATETIVPVYFALEDEELLSIYTQTQISSSSQ--GSSSAAEVLLHTATANGFQMVTSGAQSKAVSDWAITSLEGRLTG-----------SGGEDLPTIVLVAHYDSFGVAPWLSYGADSNGSGVAILLELARLFSRLYSYKRTHAGYNLLFFLSGGGKFN-YQGTKRWLEDNLDHTDASLLQDNVAFVLCLDTLGN------SDNLHLHVSKPPKEGSPQYTLLKELETVVAHQHPDLKFAMVHKKINLADDTLAWEHERFGIRRLPAFTLSHLESHRSPARHSIMDMRSVSPSLEGAGEATTGPHVDLGKLSRNTKVIAETLARVIYNLTEKGVTGDLEIFTEQMQVQEDQLASLVDWLTAQPRAAQLLDKDSSIINTLEHQLSRYLKDVKRHLVRADKRDPEFVFYDQLKQTMNAYRVKPAIFDLLLAVCIASYLGVLYLAIQNFGLLYGFLRRVTAPRVKQH--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VKZ7-1", "uniprot_id": "Q9VKZ7_DROME", "id": "Q9VKZ7-1", "name": "Nicalin", "aln": "-MMNEADSLTEIFRGGLPHCLLIVFS---LLLTCSP----VMPSEFEVISMSKYDLNGQHYGSRVASISLEARSLYSWNTSRHCVLTRLTDLSIHDFDK-LRQGAGGLILMLPANILNLDPETKELITILEQSMLTHTAAVPIYFAPYNKDLEKIIDDITYTTTDSPGQNQTALAQLVVTVSANRYHINVGGGSIAANKNSKIPIIHGELIPNQLALKPTESVADGQKLPVILITANLKTFGIYNDYPVNAD-----AAVLLVLMELFSKLHYTSSMAPKYRLRFLLSDAGVLLNFQGSKKWLEVDDN------ALQNVEFVLCLDTISESLSYTTENALYMHVSKPPKDKTSISNFFKLLKSSAEKYSNGLAVEGVHKKINLADTKLAWEHERFSIKRYPSFTLSSVKSPRSPIRTTIFKNDES---------------RLVEHTLNTTRIIAEALASFMYKVDPTSS-----IFEGQLAIKEENILPYFGVKSILHN------------NDVKDAFEKYLNNVKIIYDKPDARDPEFMFYNENEVKLNVYRVKPAIFDLFLTFVIGAYLLAVFLAIQYFPRFYDEVSKLTKEDPAGQSNGHSSERVRMKSH", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : .: * :::: . :::* :*... . ** * *.:***:** **:* * :. ***:: : **:**: ** *:* ..::* ***.**.::::** : : : . : :* .:*: : **:*** :: * .* : :::.. . :* *: *.:** ::: ..* . * .: *. :.*.* .*:.**.*::.*: .:**: . .** ::** * .***:*: . . *.* *: *..* : :**:*:*** . : :** *******:.. . * :******:: : ::: *: . : : . ***:****: ********.*:* *:**** ::. * * :*:. . ..*::***:*: .:*:: .. :* *: :::::: . .. : . . ::. :.:**::*: :.* *****:**:: : :*.******:***:*:. *.:** : *:* * :* : :: ", "identical_positions": 160, "similar_positions": 190, "identity": "26.1%" }, { "cls_id": "homologset.agr.RGD:1309357", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "D4A1J9-1", "uniprot_id": "LRFN5_RAT", "id": "D4A1J9-1", "name": "Leucine-rich repeat and fibronectin type-III domain-containing protein 5", "aln": "MEKFLFYLFLIGIAVRAQICPKRCVCQILSPNLATLCAKKGLLFVPPNIDRRTVELRLADNFVTNIKRKDFANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKITNDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEKMVSLHTLSLDHNMIDNIPKGTFSHLHKMTRLDVTSNKLQKLPPDPLFQRAQVLATSGIISPSTFALSFGGNPLHCNCELLWLRRLSREDDLETCASPALLTGRYFWSIPEEEFLCEPPLITRHTHEMRVLEGQRATLRCKARGDPEPAIHWISPEGKLISNATRSLVYDNGTLDILITTVKDTGAFTCIASNPAGEATQTMDLHIIKLPHLLNSTNNIHEPDPGSSDISTSTKSGSNASSSNGDTKMSQDK-IVVAEASSSTALLKFNFQRNIPGIRMFQIQYNGTYDDTLVYRMIPPTSKTFLVNNLASGTMYDLCVLAIYDDGITSLTATRVVGCIQFTTEQDYVRCHFMQSQFLGGTMIIIIGGIIVASVLVFIIILMIRYKVCNNNGQHKVTKVSNVYSQTNGAQMQGCSVTLPQS------MSKQAMGHEENAQCCKVASDSAIQSSETCSSQDSSTTTSALPPTWTSS-APVSQKQKRKTGTKPS---AEPQSEAVTNVESQNTNRNNSTALQLAS---CPPDSVTEGPTSQRAHTKP----------------------------------------------NALLTNVDQNVQETQR---------LESI-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BXA0-1", "uniprot_id": "LRFN5_MOUSE", "id": "Q8BXA0-1", "name": "Leucine-rich repeat and fibronectin type-III domain-containing protein 5", "aln": "MEKFLFYLFLIGIAVRAQICPKRCVCQILSPNLATLCAKKGLLFVPPNIDRRTVELRLADNFVTNIKRKDFANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKITNDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEKMVSLHTLSLDHNMIDNIPKGTFSHLHKMTRLDVTSNKLQKLPPDPLFQRAQVLATSGIISPSTFALSFGGNPLHCNCELLWLRRLSREDDLETCASPALLTGRYFWSIPEEEFLCEPPLITRHTHEMRVLEGQRATLRCKARGDPEPAIHWISPEGKLISNATRSLVYDNGTLDILITTVKDTGAFTCIASNPAGEATQTVDLHIIKLPHLLNSTNHIHEPDPGSSDISTSTKSGSNASSSNGDTKMSQDK-IVVAEATSSTALLKFNFQRNIPGIRMFQIQYNGTYDDTLVYRMIPPTSKTFLVNNLASGTMYDLCVLAIYDDGITSLTATRVVGCIQFTTEQDYVRCHFMQSQFLGGTMIIIIGGIIVASVLVFIIILMIRYKVCNNNGQHKVTKVSNVYSQTNGAQMQGCSVTLPQS------MSKQAMGHEENAQCCKVASDNAIQSSETCSSQDSSTTTSALPPTWTSS-APVSQKQKRKTGTKPS---AEPQSEAVTNVESQNTNRNNSTALQLAS---CPPDSVTEGPTSQRAHTKP----------------------------------------------NALLTNVDQNVQETQR---------LESI-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96NI6-1", "uniprot_id": "LRFN5_HUMAN", "id": "Q96NI6-1", "name": "Leucine-rich repeat and fibronectin type-III domain-containing protein 5", "aln": "MEKILFYLFLIGIAVKAQICPKRCVCQILSPNLATLCAKKGLLFVPPNIDRRTVELRLADNFVTNIKRKDFANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKITNDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEKMVSLHTLSLDHNMIDNIPKGTFSHLHKMTRLDVTSNKLQKLPPDPLFQRAQVLATSGIISPSTFALSFGGNPLHCNCELLWLRRLSREDDLETCASPPLLTGRYFWSIPEEEFLCEPPLITRHTHEMRVLEGQRATLRCKARGDPEPAIHWISPEGKLISNATRSLVYDNGTLDILITTVKDTGAFTCIASNPAGEATQIVDLHIIKLPHLLNSTNHIHEPDPGSSDISTSTKSGSNTSSSNGDTKLSQDK-IVVAEATSSTALLKFNFQRNIPGIRMFQIQYNGTYDDTLVYRMIPPTSKTFLVNNLAAGTMYDLCVLAIYDDGITSLTATRVVGCIQFTTEQDYVRCHFMQSQFLGGTMIIIIGGIIVASVLVFIIILMIRYKVCNNNGQHKVTKVSNVYSQTNGAQIQGCSVTLPQS------VSKQAVGHEENAQCCKATSDNVIQSSETCSSQDSSTTTSALPPSWTSS-TSVSQKQKRKTGTKPS---TEPQNEAVTNVESQNTNRNNSTALQLAS---RPPDSVTEGPTSKRAHIKP----------------------------------------------NALLTNVDQIVQETQR---------LELI-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1Q9H7-1", "uniprot_id": "F1Q9H7_DANRE", "id": "F1Q9H7-1", "name": "", "aln": "MEKLLVCLLVIGMAVKAQICPKRCVCQVLSPNLATLCAKKGLLFVPPNIDRHTVELRLADNFVTSVKRKDLANMTKLVDLTLSRNTISYITPHAFADLENLRALHLDHNRLTRIANDTFSGMSKLHHLILNNNQLTLIHMGAFNDLLALEELDLSYNNLETIPWEAIQRMTSLHTLSLDHNMIEYIPEGTFSLLQKLNRLDVTSNKLQKLPPDPLFQRAQVLATSGIMNPSSFALSFGGNPLHCNCELLWLRRLNREDDLETCATPLHLSGRYFWSIPEEEFLCEPPLITRHSHEMRVLEGQRVALKCKARGDPEPAIHWISPEGKLVSNTSRTLVYNNGTLDILISTVKDTGSFTCISSNPAGEAHQTIELVIIKLPHISNSTNNIQEPDPGSSDISTSTRAGANGGNHTGDTKTSSDKRVVMAEATSSTALIKFNFQRNIPGIRMFQIQYNGTYDDSLVYRMIPPTSKNFLVNNLAAGTQYDLCVLAIYDDGMTSLTATRVVGCVQFTTESEYLRCHFMQSQFLGGTMIIIIGGIIVASVLVFIIILMIRYKVCNSGDAAKGTSVIDVHSQTNGA--QGCTVTPSASKQGALSLEEGEGGKKSSAAPLPPPPDSQTHTSETSIP-DCSTSTSTVSQSWATPGSSGSLKPKRKPAPKPVPTAEQPKAEVLPNAETQNTNRNNSTALYQPAPLPPPPSRFKDTPILRRARPSTSKYMTLPVEGAWAKRRYSLNENLSKHHCYIGSQKLGNVFCKRSMSMNGMLVQMANSNLDSEKAAFSSSEWILESTV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:*. *::**:**:***********:***********************:************.:****:****.************:*********.*******: ****:*:** ***:*:************** **:*::*****************:*:::*.************: **:**** *:*:.*****************************:.**:**********************.*********:* *:**********************:**********.:*:********************:**::*:***:********:******:****:******* * ::* ******: ****:*:*************::*:* .. .**** *.** :*:***:*****:************************:***********.*******:** ************:***********:*****.:*:*****************************************... * *.* :*:****** ***:** . * :.: *::..* ..*. ::***. . *.**:**::. :*::. :. * * ***...** :*: *.:.*.*:*********** .: **. ..: * :**: .. *.:*.:: : :::: ** ", "identical_positions": 523, "similar_positions": 137, "identity": "66.29%" }, { "cls_id": "homologset.agr.RGD:1309358", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "O95487-1", "uniprot_id": "SC24B_HUMAN", "id": "O95487-1", "name": "Protein transport protein Sec24B", "aln": "MSAPAGSSHPAASARIPPKFGGAAVSGAAAPAGPGAGPAPHQQNGPAQNQMQVPSGYGLHHQNYIAPSGHYSQGPGKMTSLPLDTQCGDYYSALYTVPTQNVTPNTVNQQPGAQQLYSRGPPAPHIVGSTLGSFQGAASSASHLHTSASQPYSSFVNHYNSPAMYSASSSVASQGFPSTCGHYAMSTVSNAAYPSVSYPSLPAGDTYGQMFTSQNAPTVRPVKDNSFSGQNTAISHPSPLPPLPS--------QQHHQQQSLSGYSTLTWSSPGLPSTQDNLIRNHTGSLAVANNNPTITVADSLSCPVMQNVQPPKSSPVVSTVLSGSSGSSSTRTPPTANHPVEPVTSVTQPSELLQ------------------------------------------QKGVQYGEYVNNQASSAPTPLSSTSDDEEEEEEDEEAGVDSSSTTSSASPMPNSYDALEGGSYPDMLSSSASSPAPDPAPEPDPASAPAPASAPAPVVPQPSKMAKPFGYGYPTLQPGYQNATAPLISGVQPSNPVYSGFQQYPQQYPGVNQLSSSIGGLSLQSSPQPESLRPVNLTQERNILPMTPVWAPVPNLNADLKK-LNCSPDSFRCTLTNIPQTQALLNKAKLPLGLLLHPFRDLT----QLPVITSNTIVRCRSCRTYINPFVSFIDQ-RRWKCNLCYRVNDVPEEFMYNPLTRSYGEPHKRPEVQNSTVEFIASSDYMLRPPQPAVYLFVLDVSHNAVEAGYLTILCQSLLENLDKLP-GDSRTRIGFMTFDSTIHFYNLQEGLS-----------------------------QPQMLIVSDIDDVFLPTP-DSLLVNLYESKELIKDLLNALPNMFTNTRETHSALGPALQAAFKLMSPTGGRVSVFQTQLPSLGAGLLQSREDPNQRSSTKVVQHLGPATD-FYKKLALDCSGQQTAVDLFLLSSQYSDLASLACMSKYSAGCIYYYPSFHYTHNPSQAEKLQKDLKRYLTRKIGFEAVMRIRCTKGLSMHTFHGNFFVRSTDLLSLANINPDAGFAVQLSIEESLTDTSLVCFQTALLYTSSKGERRIRVHTLCLPVVSSLADVYAGVDVQAAICLLANMAVDRSVSSSLSDARDALVNAVVDSLSAY--GSTVSNLQHSA-LMAPSSLKLFPLYVLALLKQKAFRTGTSTRLDDRVYAMCQIKSQPLVHLMKMIHPNLYRIDRLTDEG---AVHVN-------DRIVPQPPLQKLSAEKLTREGAFLMDCGSVFYIWVGKGCDNNFIEDVLGYTNFASIPQKMTHLPELDTLSS-ERARSFITWLRDSR----------------PLSPILHIVKDESPAKAEFFQHLIEDRTEAAFSYYEFLLHVQQQICK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LR69-1", "uniprot_id": "A0ABK0LR69_RAT", "id": "A0ABK0LR69-1", "name": "", "aln": "MSAPAGSPHPAAGARMPPKLGGAVS-----------GLAPPQQNGPAQSQMQVPSGYGLPHQNYMAPSGHYSQGPGKMTSLPLDNQCENYYSRPYTAPTQNVGTPSSANQPGAQLMYGRGPSAPHMGASMPGPFQGAPASASHSYPSASQPYSSLGNRYSSPATYSATASVASQGYPSTCSHYPISTVSNVVYPNVSYPSLPASEPYGQMFTSQSAPPPARPLKESYSGPSTAVAYPSRPPPPPSQHQQQQQQQQQQQQQSHSGYSSLPWSGPGLPPAQDSLIRNQMGSLAIPNSHPAIN----------ENVQPPKPSSVVATVLPGPS---STRMPPAPSHPVGPVPSAPPPPEQMQTKVRFPVPSHAGCGKWRPVNRDPGLWGTYIGRMRERPPEKFANKGMQYGDYVNNQASSTPTPLSSASDDEEEEDEDEEAGVDSSSTTSSASPLPNSYDALEGGSYPDMHSSSASSPVPDRAPEPNSTLVPTPTAA------QPAKVAKPFGYGYPTLQPAYQNAAAPPTT-AHPSGPAYSG---YPQQYPGVHQLSSGLGGLSLQSSPQPESLRPVNLTQEKNILPATPIWAPVPNLSAELSK-LNCSPDSFRCTLTSIPQTQALLNKAKLPLGLLLHPFRDLT----QLPVITSNTIVRCRSCRTYINPFVSFIDQ-RRWKCNLCYRVNDVPEEFLYNPLTRSYGEPHKRPEVQNSTVEFIASSDYMLRPPQPAVYLFVLDVSHNAVEAGYLTVLCQSLLENLDKLP-GDSRTRIGFMTFDSTIHFYNLQEGLS-----------------------------QPQMLIVSDIDDVFLPTP-DSLLVNLYESKELIKDLLNALPNMFINTRETHSALGPALQAAFKLMSPTGGRVSVFQTQLPSLGAGLLQSREDPNQRSSTKVVHHLGPATD-FYKKLALDCSGQQTAVDLFLLSSQYSDLASLACMSKYSAGCIFYYPSFHSTHNPSQAEKLQKDLKRYLTRKIGFEAVMRIRCTKGLSMHTFHGNFFVRSTDLLSLANINPDAGFAVQLSIEESLADTSLVCFQTALLYTSSKGERRIRVHTLCLPVVSSLADVYAGVDVQAAICLLANMAVDRSVSSSLSDARDALVNAVVDPLSAY--SSAVSSVPRST-LTAPSSLKLLPLYVLALLKQKAFRTGTSTRLDDRVYAMCQMKSQPLVHLMKMIHPNLYRIDRLTDEG---AIHVN-------DRVVPQPPLQKLSAEKLTREGAFLMDCGSVFYIWIGKGCDSNFIENVLGYPDFGSIPQKMTHLPELDTLPS-ERTRSFVTWLRDSR----------------PLSPVLHVVKDESPARTDFFQHLVEDRTEAALSYYEFLIHVQQQVCK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A1Z813-1", "uniprot_id": "A1Z813_DROME", "id": "A1Z813-1", "name": "", "aln": "MSTYNPNFVPPAHAPMPLNGNNFVN---------GVQGSVQQQPGPPPGQQYIPQ--KQPQQFQQPPPAAAFPGAGAPGNVPPPQQFNSGITNQFLPPTSGAATPLQQLPPSTLPPHLRPP-------------------------AANGPPLTNGSNGASSANSSRTASPRPVGAAPQYAQGPIAAALN-------NPPLASGLRPSPQPTHQSLANLTSNLENLNLNTTRANGGTSILPQPQT----QQQYAPTVTQKDGRGVASAQTGPPQFNDANSLLAASGVAAALVPNAMATPFS----------GQKPPNLAPNPAKMFGSAS--MAGRPTPAGQRIPYGVPPPTNPEQQSQ---------------------------------------------------QNNNLQNAPPPPRVG-------------AVWPPSLPNVAAPGAQPMMPPAQQTPQTYPYSQVYQPGPQQQPPPPQSAVQPPPPG-------------MFGTQPTGAPLQYQAQAPPQAYGQHPQQ--------APQTAPGGPYGTTAPLNVAQQGFSRLWGQDTIDLMQNRHILTPATLPPPKVVLHNQFHESINCSPSIMRCTLTKIPESNSLLQKSRLPLGIVIHPFRDVN----SLPVIQCINIVRCRLCRTYINPFVYFVDS-KMWKCNLCYRVNELPDDFQFDPATKTYGDVTRRPEVRSSTIEFIAPSEYMLRPPQPAMYLFLFDVSIIAQQSGYLEAACAVLNRHLDEMP-GDARTQVGFICFDSFVHFYSMAEGLN-----------------------------QPHEMTLLDIEDPFLPRP-DSLLVNLKECKELVRDLLKQLPKRFAHTHDPGSALGAALQVAFKLMQASGGRITVFQSCLPNKGPGALEPREDPNNRS-AKDVAHLNPATD-FYKRFALECSGYQIACDLFLMNQQYSDMATISGISKHSGGCVHHFPLYQKTK-PHMVESFRSCFKRYLTRKIGFEAVMRIRCTRGLQVHTFHGNFFVRSTDLLSLPNVNPDAGYGMQISYEESLTDAKTICFQAALLYTNSEGERRIRVHTVCLPVTASLPEVMHSADTEAIIGLLSKMAVDRSVASNLSDARDAFINATIDVYNAFKIAQNLPSGQSGQ-LIAPRSLALLPLYILALLKHPAFRVGTSTRLDDRVYAMDCMKTLPLDQLMKYVYPELYKIDALIYHARNSNISSNQDDDEDEDEPLPELPRLQLSAEHLDSRSIFLMDCGTLIMIYVGLNVPPDVLEAVLGISSTAELGDYVYGLPNVVSNEN-DVLKRFILRLNYDK----------------PYSALVQIIRDTSTAKGQFTERLTDDRSESSLSYYEFLQHIRAQVK-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53953-1", "uniprot_id": "SFB2_YEAST", "id": "P53953-1", "name": "SED5-binding protein 2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSHHKKRVYPQAQVPY--------------------------------------------IASMP----IVAEQQQSQQQIDQTAYAMG-----------NLQLNNR----ANSFTQ----------LAQNQQ---FPGSG---------------------------------------------------------------------------------------------------------KVVNQLYPVDLFTELPPPIRDLSLPPLPITISQ------------------------------------------------------------------------------------------DNIVTPSEYS--------------NVPYQYVRSTLKAVPKTNSLLKKTKLPFAIVIRPYLHLQDSDNQVPLNTDGVIVRCRRCRSYMNPFVVFINQGRKWQCNICRFKNDVPFGFDQNLQGAPI-NRYERNEIKNSVVDYLAPVEYSVREPPPSVYVFLLDVSQNAVKNGLLATSARTILENIEFLPNHDGRTRIAIICVDHSLHYFYVPLDDDYEVSDEDDEESDGEEEDEDEEEEDVDNSETIQMFDIGDLDEPFLPMPSDELVVPLKYCKNNLETLLKKIPEIFQDTHSSKFALGPALKAASNLIKSTGGKVEVISSTLPNTGIGKLKKRSEQGILNTPKESSQLLSCKDSFYKTFTIECNKLQITVDMFLASEDYMDVATLSHLGRFSGGQTHFYPGFNATS-LNDVTKFTRELSRHLSMDISMEAVMRVRCSTGLRATSFFGHFFNRSSDLCAFSTMPRDQSYLFGISIEDSLMAEYCYLQVSTLLTLNT-GERRIRVMTLALPTSESAREVFASADQLAITDFMTQNAVTKALNSSMYSARDFITKSLEDILNAYKKEISMSNINSVTSLNLCANLRMLPLLMNGLSKHIALRPGVVP-SDYRASALNRLETEPLHYLIKSIYPTVYSLHDMPDEVGLP----------DFEGKTVLPEPINATISLFERYGLYLIDNSAELFLWVGGDAVPELLIDVFNTDTISQIPVGKSELPLLNDSPFNERLRRIIGRIRENNDTITFQSLYIIRGPSINEPANLNSEKDMASLRLWVLSTLVEDKVLNCASYREYLQSMKTSINR", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P40482-1", "uniprot_id": "SEC24_YEAST", "id": "P40482-1", "name": "Protein transport protein SEC24", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSHHKKRVYPQAQLQYGQNATPLQQPAQFMPPQD--------PAAAGMSYGQMGMPPQGAVPSMGQQQFLTPAQEQLHQQIDQATTSMN-----------DMHLHNVPLVDPNAYMQPQVPVQMGTPLQQQQQPMAAPAYGQPSAAMG-----------------------------------------------------------------------------------------------QNMRPMNQLYPIDLLTELPPPITDLTLPPPPLVIPP------------------------------------------------------------------------------------------ERMLVPSELS--------------NASPDYIRSTLNAVPKNSSLLKKSKLPFGLVIRPYQHLYDDIDPPPLNEDGLIVRCRRCRSYMNPFVTFIEQGRRWRCNFCRLANDVPMQMDQSDPNDPK-SRYDRNEIKCAVMEYMAPKEYTLRQPPPATYCFLIDVSQSSIKSGLLATTINTLLQNLDSIPNHDERTRISILCVDNAIHYFKIPLDS------ENNEES----------------ADQINMMDIADLEEPFLPRP-NSMVVSLKACRQNIETLLTKIPQIFQSNLITNFALGPALKSAYHLIGGVGGKIIVVSGTLPNLGIGKLQRRNESGVVNTSKETAQLLSCQDSFYKNFTIDCSKVQITVDLFLASEDYMDVASLSNLSRFTAGQTHFYPGFSGKN-PNDIVKFSTEFAKHISMDFCMETVMRARGSTGLRMSRFYGHFFNRSSDLCAFSTMPRDQSYLFEVNVDESIMADYCYVQVAVLLSLNN-SQRRIRIITLAMPTTESLAEVYASADQLAIASFYNSKAVEKALNSSLDDARVLINKSVQDILATYKKEIVVSNTAGGAPLRLCANLRMFPLLMHSLTKHMAFRSGIVP-SDHRASALNNLESLPLKYLIKNIYPDVYSLHDMADEAGLPVQTEDG----EATGTIVLPQPINATSSLFERYGLYLIDNGNELFLWMGGDAVPALVFDVFGTQDIFDIPIGKQEIPVVENSEFNQRVRNIINQLRNHDDVITYQSLYIVRGASLSEPVNHASAREVATLRLWASSTLVEDKILNNESYREFLQIMKARISK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . : . : : : . : : .. .: . :. * : * .:: : * . . .*.**. :*:..:**:*::**:.::::*: .: *: ***** **:*:**** *::. : *:**:* *::* : . . . * *:: :.::::*. :* :* * *: * *::*** : : * * : .::: :* * **::.:: .* :*:: : . : : : *::: *** * :.::* * .:: :. **. :*: * . . ***.**: * :*: **:: *.. **. * * *: *.: . . .* :* .. * *** ::::*. * : *:** ..:* *:*::: :.:.:.* ..:* : . .: : :::: .: :*:*** * : ** *.*:** **:** ::..: * .: . :. ::*: :.** .. .:****: *:.:*. * :* ..* * : . ** ::: *.: .** : :: * :: :.. * .* ::** : .* *: *:* * . * *. *: ::: ** *:* ::* :* :. : . : : . : . :*:* . : :::* . .: *:. .: :* : : : :: :. . :: :. : . * :*: ** *:* :: : ", "identical_positions": 160, "similar_positions": 275, "identity": "11.54%" }, { "cls_id": "homologset.agr.RGD:1309359", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K351-1", "uniprot_id": "A0A0G2K351_RAT", "id": "A0A0G2K351-1", "name": "", "aln": "MSGSNPKATTAGSQAGPGGLVAGKEEKKKAGGGVLNRLKARRQGPPHTSDDGPGTAVTEQELLALD-TIRPEHVLRLNRVTENYLCKPEDNVYSIDFTRFKIRDLETGTVLFEIAKPCISDQDQ------------DTEEESVDVDISVGRFVRYQFTPAFLRLRTVGATVEFTVGDRPVTGFRMIERHYFRERLLKTFDFDFGFCIPSSRNT--------------FRLMIENPYETRSDSFYFVDNKLIMHNKADYAYNGGQ--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C4B4-1", "uniprot_id": "U119B_MOUSE", "id": "Q8C4B4-1", "name": "Protein unc-119 homolog B", "aln": "MSGSNPKAATAGSQAGPGGLVAGKEEKKKAGGGVLNRLKARRQGPPHTPDDGSGAAVTEQELLALD-TIRPEHVLRLNRVTENYLCKPEDNVYSIDFTRFKIRDLETGTVLFEIAKPCISDQDQ------------DAEEESVDVDISVGRFVRYQFTPAFLRLRTVGATVEFTVGDRPVTGFRMIERHYFRERLLKTFDFDFGFCIPSSRNTCEHIYEFPQLSEDVIRLMIENPYETRSDSFYFVDNKLVMHNKADYAYNGGQ--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NIH7-1", "uniprot_id": "U119B_HUMAN", "id": "A6NIH7-1", "name": "Protein unc-119 homolog B", "aln": "MSGSNPKAAAAASAAGPGGLVAGKEEKKKAGGGVLNRLKARRQAPHHAADDGVGAAVTEQELLALD-TIRPEHVLRLSRVTENYLCKPEDNIYSIDFTRFKIRDLETGTVLFEIAKPCVSDQEE------------DEEEGGGDVDISAGRFVRYQFTPAFLRLRTVGATVEFTVGDKPVSNFRMIERHYFREHLLKNFDFDFGFCIPSSRNTCEHIYEFPQLSEDVIRLMIENPYETRSDSFYFVDNKLIMHNKADYAYNGGQ--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q90Z08-1", "uniprot_id": "U119B_DANRE", "id": "Q90Z08-1", "name": "Protein unc-119 homolog B", "aln": "MNSQSSRNETAATAVN-GSDSAAASRDHKSGGGVLKRLKSRRNQVDRRP-------VTEEELRALGRDITPDEVLGLRAVARDYLCKLEDNIYNIDFTRFKIRDLETGTVLFEIAKPPHCDLDE------------EDDENR-DADTSAGRFVRYQFTPAFLKLRTVGATVEFTVGDQPVTNFRMIERHYFQDRLLKSFDFDFGFCIPNSRNTCEHIYEFPQLPEDLIRLMIEHPYETRSDSFYFVDNKLIMHNKADYAYNGGQ--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9XYQ2-1", "uniprot_id": "UN119_DROME", "id": "Q9XYQ2-1", "name": "Protein unc-119 homolog", "aln": "MSVVG-KQLNPVQSSGAGAVTTSSSAAAGSSSSNSGVEANGGSGGSSGAAAAGAGASGDAKRPAESSSVTPDEVLHLTKITDDYLCSANANVFEIDFTRFKIRDLESGAVLFEIAKPPSEQYPEGLSSDETMLAAAEKLSLDDTADPNAGRYVRYQFTPAFLNLKTVGATVEFTVGSQPLNNFRMIERHFFRDRLLKTFDFEFGFCFPFSKNTVEHIYEFPNLPPDLVAEMISSPFETRSDSFYFVGNRLVMHNKADYAYDGGNIV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. . : . . *. :. . :... . . : : * . : *:.** * :: :***. : *::.************:*:******** : : : . .* ..**:**********.*:***********.:*:..*******:*:::***.***:****:* *:** . **. *:**********.*:*:*********:**: ", "identical_positions": 106, "similar_positions": 62, "identity": "39.85%" }, { "cls_id": "homologset.agr.RGD:1309360", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q5FVH8-1", "uniprot_id": "R7BP_RAT", "id": "Q5FVH8-1", "name": "Regulator of G protein signaling 7-binding protein", "aln": "MSSAPNGRKKRPSRSTRSSIFQISKPPLQSGDWERRGSGSESAHKTQRALDDCKMLVQEFNTQVALYRELVISIGDVSVSCPSLRAEMHKTRTKGCEMARQAHQKLAAISGPEDGEIHPEICRLYIQLQCCLEMYTTEMLKSICLLGSLQFHRKGKEASGGAKSLDSKIEENAETPALEDSLSSPLDSQQQSWQVATDIENTERDMREMKNLLSKLRETMPLPLKNQDD-----SSLLNLTPYPMVRRR--KRRFFGLCCLVSS-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BQP9-1", "uniprot_id": "R7BP_MOUSE", "id": "Q8BQP9-1", "name": "Regulator of G protein signaling 7-binding protein", "aln": "MSSAPNGRKKRPSRSTRSSIFQISKPPLQSGDWERRGSGSESAHKTQRALDDCKMLVQEFNTQVALYRELVISIGDVSVSCPSLRAEMHKTRTKGCEMARQAHQKLAAISGPEDGEIHPEICRLYIQLQCCLEMYTTEMLKSICLLGSLQFHRKGKEASGGAKNLDSKIEENAETPALEDSLSSPLESQQQCWQVATDIENTERDMREMKNLLSKLRETMPLPLKNQDD-----SSLLNLTPYPMVRRR--KRRFFGLCCLVSS-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6MZT1-1", "uniprot_id": "R7BP_HUMAN", "id": "Q6MZT1-1", "name": "Regulator of G protein signaling 7-binding protein", "aln": "MSSAPNGRKKRPSRSTRSSIFQISKPPLQSGDWERRGSGSESAHKTQRALDDCKMLVQEFNTQVALYRELVISIGDVSVSCPSLRAEMHKTRTKGCEMARQAHQKLAAISGPEDGEIHPEICRLYIQLQCCLEMYTTEMLKSICLLGSLQFHRKGKEPGGGTKSLDCKIEESAETPALEDSSSSPVDSQQHSWQVSTDIENTERDMREMKNLLSKLRETMPLPLKNQDD-----SSLLNLTPYPLVRRR--KRRFFGLCCLISS-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08BU8-1", "uniprot_id": "R7BPA_DANRE", "id": "Q08BU8-1", "name": "Regulator of G protein signaling 7-binding protein A", "aln": "MSSAPNGRKNRP--RTAGTIFQIGG-KAPSRESERRES-SE----ALLAVSDCRMVVQEFNTLVALYRELVISIGEISADCPSLRAEMHKTRTKGCEMARTAHQNLSAISGPEDGEIHPEICRLFIQLQCCLEMYLTEMLKSVCLLGSLQLHRKGKHYLGATK-LDSRKEDSSDIPILEDTSSTPPDCPHTYFLVATDIENIERDMTEMKNLLSKLRETMPLPLKNQDD-----SSLLNLAPYPMVRQR--KRRFFGLCCLVSS-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q4V9P3-1", "uniprot_id": "R7BPB_DANRE", "id": "Q4V9P3-1", "name": "Regulator of G protein signaling 7-binding protein B", "aln": "MCSAPNGRKNRP--RSAANIFQIGK--SSVRDPERRES-TESARRAQRAMDDCRTTVQEFNTLVALHREQVISIGENTTDCPSLRAQMHKTRVKGCAVAQAAYQNLIAISGPEDGEIHPEICRLFIQLQCCLEMYITEMLKSMCLLGVLQLHRKGNDMCPELN-MDCRVDESSDVPMLEDRSSSPMDFPQDSWVVCADIENIESDMREMRNLLSKLRETMPLPLKNQDD-----SSLLNLTPYPLVRQR--KRRFSGLCCLVSG-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VPW6-1", "uniprot_id": "Q9VPW6_DROME", "id": "Q9VPW6-1", "name": "", "aln": "MAHGGGISSLAGLEEKPAACVASSTALAIRNSTIIAHRLSIYLPQLLLPSRDPQKLITEINCYVAQFRELLIFIGQAR-DSPELREKIRKLRRSCVDACKHTAHLITPQPRHCLGS--PSERMHLTLLYHLTLQFQHELIKSHRLIQLVPLDMTEYYAPSRTAPSNLG---NVISQFLLCKQINPDFQQEELCSIVKDSQELSELLEELQAHMPLTEASPEFDLDPTQKSESSLVSLNTPDWYARQRRRSCKSRSRSLCCCLARKSHKTF-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "M9PCK0-1", "uniprot_id": "M9PCK0_DROME", "id": "M9PCK0-1", "name": "", "aln": "MLTTHHLHHLHHHR--------GSTAVELDKITNLN------------------TLIVEINSHVALFRDMLIHVGQAK-DCPELREKIRKLRRTCVEALKHTAQILMPQVKSAMADGILTDNPHLVLLFYMAQLFLRELVKSYRLIQVVPMDMSGYYEN-RAGPSNLG---NVISQILLCKQFTPDFNEEELCSITKDSQDIAVLLAEMQEYMPQHEAYLERN-----------AALDTTGPWQAKRRQNYICKNMSLLCCVSRPNYLXEQADGV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . : *:* ** .*: :* :*: ..*.** :::* * . : : : : . .. * : *::** *: : :. . : . * .* . : * :: : *:: :. . :* . : *:: : .* * :: ", "identical_positions": 26, "similar_positions": 52, "identity": "9.45%" }, { "cls_id": "homologset.agr.RGD:1309361", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AA24-1", "uniprot_id": "A0A8I6AA24_RAT", "id": "A0A8I6AA24-1", "name": "", "aln": "MAVPPRPLQLLGILFILSLSSVRLAQAGAYYGIKPLPPQIPPQIPPQIPQYQPLGQQVPHMPLGKDGLSMGKEMPHMQYGKEYPHLPQYMKEIQPVPRVGKEVVPKKGK-EIPLASLRGEQGPRGEPGPR---GPPGPPGLPGHGMPGIKGKPGPQG---YPGIGKPGMPGMPGKPGAMGMPGAKGEIGPKGEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLPGQPGAKGERGPKGPPGPPGLQGPKGEKGFGMPGLPGLKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGPPGEPGPQGLIGVPGVQGPPGMPGVGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGVGKPGFPGPKGDRGIGGVPGALGPRGEKGPVGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGHKGLPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIAGPSGPIGPPGIPGPKGEPGLPGPPGFPGVGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPSPQGEYLPDMGLGIDGVKPPHAYAGKKGKNGGP--YEMPAFTAELTVPFPPVGAPVKFDKLLYNGRQNYNPQTGVFTCEVPGVYYFAYHVHCKGGNVWVALFKNNEPMMYTYDEYKKGFLDQASGSAVLLLRPGDRVFLQMPSEQAAGLYAGQYVHSSFSGYLLYPM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q00780-1", "uniprot_id": "CO8A1_MOUSE", "id": "Q00780-1", "name": "Collagen alpha-1(VIII) chain", "aln": "MAVPPRPLQLLGILFIISLNSVRLIQAGAYYGIKPLPPQIPPQIPPQIPQYQPLGQQVPHMPLGKDGLSMGKEMPHMQYGKEYPHLPQYMKEIPPVPRMGKEVVPKKGKGEVPLASLRGEQGPRGEPGPR---GPPGPPGLPGHGMPGIKGKPGPQG---YPGIGKPGMPGMPGKPGAMGMPGAKGEIGPKGEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLPGQPGAKGERGPKGPPGPPGLQGPKGEKGFGMPGLPGLKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGPPGEPGPQGLIGVPGVQGPPGMPGVGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGVGKPGFPGPKGDRGIGGVPGVLGPRGEKGPIGAPGMGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGVVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEGGHKGLPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIVGPSGPIGPPGIPGPKGEPGLPGPPGFPGVGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMP-TPSPQGEYLPDMGLGIDGVKPPHAYAGKKGKHGGPA-YEMPAFTAELTVPFPPVGAPVKFDKLLYNGRQNYNPQTGIFTCEVPGVYYFAYHVHCKGGNVWVALFKNNEPMMYTYDEYKKGFLDQASGSAVLLLRPGDQVFLQMPSEQAAGLYAGQYVHSSFSGYLLYPM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P27658-1", "uniprot_id": "CO8A1_HUMAN", "id": "P27658-1", "name": "Collagen alpha-1(VIII) chain", "aln": "MAVLPGPLQLLGVLLTISLSSIRLIQAGAYYGIKPLPPQIPPQMPPQIPQYQPLGQQVPHMPLAKDGLAMGKEMPHLQYGKEYPHLPQYMKEIQPAPRMGKEAVPKKGK-EIPLASLRGEQGPRGEPGPR---GPPGPPGLPGHGIPGIKGKPGPQG---YPGVGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPHAYGAKKGKNGGPA-YEMPAFTAELTAPFPPVGAPVKFNKLLYNGRQNYNPQTGIFTCEVPGVYYFAYHVHCKGGNVWVALFKNNEPVMYTYDEYKKGFLDQASGSAVLLLRPGDRVFLQMPSEQAAGLYAGQYVHSSFSGYLLYPM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "X1WGI4-1", "uniprot_id": "X1WGI4_DANRE", "id": "X1WGI4-1", "name": "", "aln": "MAGP--LLSACLFVLVEHLCLLHHIHAGAFYGHKPLPQKRQP--LPQLPLLPHGNEGITQHHY------HGKEIPQLPFGNEMPLLPQYGKERPQFPMHMGIPIARKGE-----TVPRGQKGPPGEPGPIGLQGPRGPPGLPGHGIPGPTGKPGPQGPPGLPGIGKPGMAGLPGKPGGIGLPGPKGELGPIGGEGPIGLPGPPGLPGPHGLPGVAKPGGQGLPGQPGPRGEPGQKGFPGIPGLQGPKGENGFGLPGLPGVKGLPGLPGPPGQVGLPGIGKPGLNGLPGVPGGQGKPGAPGEPGLAGVPGERGQIGPPGLPGFGKPGLDGLPGKPGLPGGRGEPGQTGLTGGPGLPGFGKPGYPGPKGEKGHGGLPGPIGPKGEKGHGGLPGMIGLQGPSGLPGPPGLMGPPGGIGFPGPKGEGGAVGPKGLLGPKGEPGPQGLPGKPGFPGELGQPGPRGLTGPLGPKGESGHKGLPGLPGVPGKPGTKGELGFPGEKGHPGPMGIPGLIGPAGPIGPPGLPGPKGEYGPPGKPGIPGEGKPGFPGPTGPAGIPGPSGPHGPPGIPGPPGPPGLPGPRAQAS----FFGQILPETGPGLDGEKGGYKKEKPGGAIIGRHGLEMPAFTAQLTTPFPQVGQPVVFNKILHNGNQNYNLQTGIFTCKIPGIYYFVYHVNCKGNNVWVGLYRNNEPVMYTYDEYKKSYLDQASGSAVLPLNFGDTVHVQLPSEQAAGLYAGPYVHSSFSGYLLYPM", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** *. .:: * :: :***:** **** : * **:* .: :.: ***:*:: :*:* * **** ** * :.:**: : **::** ***** ** *********:** .******* **:*****.*:*****.:*:**.***:* * **:*:*** * ********:.**** *******.:*: * ** ** **:****::***:** **:** **: **** *****:****:.*:** * ****.***** * * * ****:**.**** **:**:**:***:** * .**.* *****.****:*****::* **:** :**:**** * **: * * .**** ** *****.*********** ***:* ******* **:****** **:* ** ***.**:*****.*:**:******** *.*** *:**::* ** ****: **:*******:****** * ** **:** ****..* **.* **. **:* **:******** *** * . *: **: * *:** * : * * *******:**.*** ** ** *:*:*:**.**** ***:***::**:***.***:***.****.*::****:*********.:********** *. ** *.:*:*********** **************", "identical_positions": 456, "similar_positions": 123, "identity": "60.64%" }, { "cls_id": "homologset.agr.RGD:1309363", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q4KM91-1", "uniprot_id": "CDCA7_RAT", "id": "Q4KM91-1", "name": "Cell division cycle-associated protein 7", "aln": "MEARRARQKALKVKN-LKNVRYMKLISVETSSSS-DDSCDSFASDNFANTR-------------------------------------------LQFNREGCRTRSQCRPSGPLRVAMKFPARNTRRAANTKAAPPKPSESSANDSHSESDSEEEE----DGMNFLEKRALNIKQNKAMLAKLMSELESFPGIFSGRHSL-PGHRTKDSKSPRRRTFPGVASRRNPERRARPLTRSRSRILGSLGALPTEEEEDEEEEE-DKYMLVRR-RKSVDGYMNDDDVSRSRRP-GSMTLPHIIRPVEDVTEEEIRNICSNSREKIYNRSLGSTCHQCRQKTTDTKTNCRNPDCWGIRGQFCGPCLRNRYGEEVKDALLDPNWHCPPCRGICNCSFCRQRDGRCATGVLVYLAKYHGFGNVHAYLKSLKQEFEMQA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D0M2-1", "uniprot_id": "CDCA7_MOUSE", "id": "Q9D0M2-1", "name": "Cell division cycle-associated protein 7", "aln": "MEARRARQKALKVKN-LKDVRYMKLISMETSSSS-DDSCDSFASDNFANTR-------------------------------------------LQLNREGCRTRSQCRHSGPLRVAMKFPARNTRRAASKKAAPPKPSESSANDSHSDSEEEEEEEEEEDGMNFLEKRALNIKQNKAMLAKLMSELESFPGLFSGRHSL-PGHRAKDSKSPRRRTFPGVATRRNPERRTRPLTRSRSRILGSLGALPTEEEEEEEEEEEDKYMLVRQ-RKSMDSYMNDDDVPRSRRP-GSMTLPHIIRPVEEVTEEEIRNICSNSREKIYNRSLGSTCHQCRQKTTDTKTNCRNPDCWGIRGQFCGPCLRNRYGEEVKDALLDPNWHCPPCRGICNCSFCRQRDGRCATGVLVYLAKYHGFGNVHAYLKSLKQEFEMQA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BWT1-1", "uniprot_id": "CDCA7_HUMAN", "id": "Q9BWT1-1", "name": "Cell division cycle-associated protein 7", "aln": "MDARRVPQKDLRVKKNLKKFRYVKLISMETSSSS-DDSCDSFASDNFANTR-------------------------------------------LQSVREGCRTRSQCRHSGPLRVAMKFPARSTRGATNKKAESRQPSENSVTDSNSDS---EDE----SGMNFLEKRALNIKQNKAMLAKLMSELESFPGSFRGRHPL-PGSDSQ-SRRPRRRTFPGVASRRNPERRARPLTRSRSRILGSLDALPMEEEEEE-----DKYMLVRK-RKTVDGYMNEDDLPRSRRSRSSVTLPHIIRPVEEITEEELENVCSNSREKIYNRSLGSTCHQCRQKTIDTKTNCRNPDCWGVRGQFCGPCLRNRYGEEVRDALLDPNWHCPPCRGICNCSFCRQRDGRCATGVLVYLAKYHGFGNVHAYLKSLKQEFEMQA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BET8-1", "uniprot_id": "A0A8M2BET8_DANRE", "id": "A0A8M2BET8-1", "name": "", "aln": "MRSKKQQASPPSTRMNLRSYRSSTVLPMETSSSSSDDSCDSFGSDGFGNSKRPQRQTRSSTQMEKVFNVLPVTEEEDACSGFESELNDELTEMKMDSDAEACSPPRKTRKSFTLRVAMKFPTK--RSSPSKPVKPEPKPKAETKDPESDS----------EGENFMLKRALNIKENKAMLAKLMAELDKVPGLFPGRAALTPGNVVR--RVPRRSLEPIAARRRNPERTSRPHTRSRSLVDGPP--SPPPEDEEE-----DKYSLVRRSRGYEDDDEEEQKEPRRRSYNSSLTIPHVVRPVEDITEAELENICINVREKTYNRATGSTCHQCRQKTTDTKTNCRNSECVGVRGQFCGPCLRNRYGEEVRDALLNPEWLCPPCRGICNCSFCRAREGRCATGVLVYLAKYHGYDNVHSYLKSLKKELEESE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* ::: . .: *:. * .::.:****** *******.**.*.*:: :: *.* . : * * .********:: * :... . . .: ...*..*:* .* **: *******:*********:**:..** * ** .* ** : : *** * .* ****** :** ***** : *. * *:*:* *** ***: * *. :::. .* * .*:*:**::****::** *:.*:* * *** ***: *********** ********.:* *:*****************:****:*:* ************** *:****************:.***:******:*:* . ", "identical_positions": 204, "similar_positions": 87, "identity": "47.44%" }, { "cls_id": "homologset.agr.RGD:1309364", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q91Y47-1", "uniprot_id": "FA11_MOUSE", "id": "Q91Y47-1", "name": "Coagulation factor XI", "aln": "MTSLHQVLYFIFFASVSSECVTKVFKDISFQGGDLSTVFTPSATYCRLVCTHHPRCLLFTFMAESSSDDPTKWFACILKDSVTEILPMVNMTGAISGYSFKQCPQQLSTCSKDVYVNLDMKGMNYNSSVVKNARECQERCTDDAHCQFFTYATGYFPSVDHRKMCLLKYTRTGTPTTITKLNGVVSGFSLKSCGLSNLACIRDIFPNTVLADLNIDSVVAPDAFVCRRICTHHPTCLFFTFFSQAWPKESQRHLCLLKTSESGLPSTRITKSHALSGFSLQHCRHSVPVFCHPSFYNDTDFLGEELDIVDVKGQETCQKTCTNNARCQFFTYYPSHRLCNERNRRGRCYLKLSSNGSPTRILHGRGGISGYSLRLCKMDNVCTTKINPRVVGGAASVHGEWPWQVTLHIS---QGHLCGGSIIGNQWILTAAHCFSGIETPKKLRVYGGIVNQSEINEGTAFFRVQEMIIHDQYTTAESGYDIALLKLESAMNYTDFQRPICLPSKGDRNAVHTECWVTGWGYTALRGEVQSTLQKAKVPLVSNEECQTRYRRHKITNKMICAGYKEGGKDTCKGDSGGPLSCKYNGVWHLVGITSWGEGCGQKERPGVYTNVAKYVDWILEKTQTV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K4I9-1", "uniprot_id": "A0A0G2K4I9_RAT", "id": "A0A0G2K4I9-1", "name": "", "aln": "MTSLQQVLYFIFFASVSSECITKVFKDISFQGGDLSTVFTPSATYCQLVCTHHPRCLLFTFMAESSSDDPTKWFACILKDSLTETLPMVHMTGAVSGYSFKQCPQQLSACSKNVYVNLDMKGMNYNSSAVKNARECQERCTNDAHCQFFTYATGHFPSVDHRKMCLLKYTQMGTPTSITKLDSVVSGFSLKSCGLSNLACIRDIFPNTVLADLNIDSVLAPDAFVCRRICTHHPTCLFFTFFTQAWPKESQRHLCLLKTSESGFPSTRITKSNALSGFSLQHCRHSIPVFCHPNFYNDTDFLGEELDIVDVKGKESCQKMCSDNVRCQFFTYYPSRGSCSE--RKGRCYLKLSSNGSPTRILHGRGGISGYTLRLCKMDNVCTTKIRPRVFGGAASVHGEWPWQVTLHTT---QGHLCGGSIIGNRWILTAAHCFSGTETPKTLRVYGGIVNQSEINEDTTFFRVQEMIIHDQYTSAESGFDIALLKLEPAMNYTD--------------------------------EVQSTLQKAKVPLVSNEECQTRYRKHKITNKVICAGYKEGGKDTCKGDSGGPLSCKHNGVWHLVGITSWGEGCGQKERPGVYTNVAKYVDWILEKTQSE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P03951-1", "uniprot_id": "FA11_HUMAN", "id": "P03951-1", "name": "Coagulation factor XI", "aln": "MIFLYQVVHFILFTSVSGECVTQLLKDTCFEGGDITTVFTPSAKYCQVVCTYHPRCLLFTFTAESPSEDPTRWFTCVLKDSVTETLPRVNRTAAISGYSFKQCSHQISACNKDIYVDLDMKGINYNSSVAKSAQECQERCTDDVHCHFFTYATRQFPSLEHRNICLLKHTQTGTPTRITKLDKVVSGFSLKSCALSNLACIRDIFPNTVFADSNIDSVMAPDAFVCGRICTHHPGCLFFTFFSQEWPKESQRNLCLLKTSESGLPSTRIKKSKALSGFSLQSCRHSIPVFCHSSFYHDTDFLGEELDIVAAKSHEACQKLCTNAVRCQFFTYTPAQASCNE--GKGKCYLKLSSNGSPTKILHGRGGISGYTLRLCKMDNECTTKIKPRIVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYSGILNQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVNYTDSQRPICLPSKGDRNVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQKRYRGHKITHKMICAGYREGGKDACKGDSGGPLSCKHNEVWHLVGITSWGEGCAQRERPGVYTNVVEYVDWILEKTQAV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * **::**:*:***.**:*:::** .*:***::*******.**::***:********* ***.*:***:**:*:****:** ** *: *.*:********.:*:*:*.*::**:*****:*****..*.*:*******:*.**:****** ***::**::****:*: **** ****: **********.***************:** *****:******* ******* *******:* *******:**********:*****.**:******** ****:*****..**:************ .*.:*:*** *:: .******* *:: *.* :*:************:***********:******** *****.**:.**:***:********** : * **********:********* * *:** ****.**:*****:*.*:** ***:******. ****:********.::**** ::*.******:***:*****.*** ****:*:*****:*****:************:* **************.*:*********.:**********: ", "identical_positions": 444, "similar_positions": 110, "identity": "70.81%" }, { "cls_id": "homologset.agr.RGD:1309366", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z2M7-1", "uniprot_id": "PMM2_MOUSE", "id": "Q9Z2M7-1", "name": "Phosphomannomutase 2", "aln": "--MAT---------LCLFDMDGTLTAPRQKITEEMDGFLQ-KLRQKTKIGVVGGSDFEKLQEQL-GNDVVEKYDYVFPENGLVAYKDGKLLCKQNIQGHLGEDVIQDLINYCLSYIANIKLPKKRGTFIEFRNGMLNVSPIGRSCSQEERIEFYELDKKEHIRQKFVADLRKEFAGKGLTFSIGGQISIDVFPEGWDKRYCLRHLEHA-GYKTIYFFGDKTMPGGNDHEIFTDPRTVGYTVTAPEDTRRICEGLFP-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7F1X7-1", "uniprot_id": "F7F1X7_RAT", "id": "F7F1X7-1", "name": "Phosphomannomutase", "aln": "--MAT---------LCLFDMDGTLTAPRQKITKEMDGFLQ-KLRQKTKIGVVGGSDFEKLQEQL-GNDVVEKYDYVFPENGLVAYKDGKLLCKQNIQGHLGEAVIQDLINYCLSYIAKIKLPKKRGTFIEFRNGMLNVSPIGRSCSQEERIEFYELDKKEHIRQKFVADLRKEFAGKGLTFSIGGQISFDVFPDGWDKRYCLRHLEQA-GYKTIYFFGDKTMPGGNDHEIFTDPRTVGYTVTAPEDTRRICEELFP-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O15305-1", "uniprot_id": "PMM2_HUMAN", "id": "O15305-1", "name": "Phosphomannomutase 2", "aln": "--MAAPGP-----ALCLFDVDGTLTAPRQKITKEMDDFLQ-KLRQKIKIGVVGGSDFEKVQEQL-GNDVVEKYDYVFPENGLVAYKDGKLLCRQNIQSHLGEALIQDLINYCLSYIAKIKLPKKRGTFIEFRNGMLNVSPIGRSCSQEERIEFYELDKKENIRQKFVADLRKEFAGKGLTFSIGGQISFDVFPDGWDKRYCLRHVEND-GYKTIYFFGDKTMPGGNDHEIFTDPRTMGYSVTAPEDTRRICELLFS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P07283-1", "uniprot_id": "PMM_YEAST", "id": "P07283-1", "name": "Phosphomannomutase", "aln": "MSIAEFAYKEKPETLVLFDVDGTLTPARLTVSEEVRKTLA-KLRNKCCIGFVGGSDLSKQLEQL-GPNVLDEFDYSFSENGLTAYRLGKELASQSFINWLGEEKYNKLAVFILRYLSEIDLPKRRGTFLEFRNGMINVSPIGRNASTEERNEFERYDKEHQIRAKFVEALKKEFPDYGLTFSIGGQISFDVFPAGWDKTYCLQHVEKD-GFKEIHFFGDKTMVGGNDYEIFVDERTIGHSVQSPDDTVKILTELFNL", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VTZ6-1", "uniprot_id": "PMM_DROME", "id": "Q9VTZ6-1", "name": "Phosphomannomutase", "aln": "MTTAALKRDE---ILLLFDVDGTLTMPRSVVTPEFEEFFYSRVKPRATIGIVGGSDLEKMFEQLNGRKILNEFDFIFPENGLVQIEGGKEVGKQNIIMHLGEETVKRFINFVLRYLSELDVPIKRGTFIEFRNGMMNVCPIGRQCTREERNMFAEYDIEHKVREKMIKDLKQEFADVDLTYSIGGQISFDVFPHGWDKTYCLRHIEAHYKFKEIHFFGDKTEPGGNDYEIYSDPRTISHRVYTPKDTQRILTEILEL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * ***:***** .* :: *. : ::: : **.*****:.* *** * .:::::*: *.****. . ** : *.: *** : : : * *::::.:* :****:******:**.****..: *** * . * :.::* *:: *::**.. .**:*******:**** **** ***:*:* :* *:****** ****:**: * **:.: * :*.** :* :: ", "identical_positions": 109, "similar_positions": 70, "identity": "42.41%" }, { "cls_id": "homologset.agr.RGD:1309367", "date": "2026-09-09 05:52:12 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LNT6-1", "uniprot_id": "A0ABK0LNT6_RAT", "id": "A0ABK0LNT6-1", "name": "", "aln": "MLALDCQLKPALPQKVFCRLWASMGKLQSKLRYSTYLY-RPDGIIEERVQTKASQEYIPAHVDTVSVVAALNSDLCISGGKDKTAVVYNWKTGHVVRRFIGHEREITKIACIPKSNQFFSASRDKTVLMWDLQGSSQPRQQLSGHAMVVTGLAVSPDSSQLCTGSRDNSLLLWDVGTGQCVERASVSRNLVTHLCWVPREPYIVQTSEDKTIRLWDCRGLQMAHVFPTKQHIQTHCEVSVDGHTCVSCSSGFGGEGCEATLWDLRQTRERMCEYKGHFQTVASCVFLPKSAALMPMIATSAHDSKVKIWNQDTGACLSTLSLDGSGPLTSLAVGDITSLLCASFYRGVHLLRMDHSRGLELQEVAAF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JHB4-1", "uniprot_id": "WDR31_MOUSE", "id": "Q9JHB4-1", "name": "WD repeat-containing protein 31", "aln": "MLLLDGQLKPALPQKVFCRLWAVMGKLQSKLRHSTYLYSRPDGIIEERVQTKAPQEYIPVHVDTVSVIATLNSDLCISGGKDKTAVAYNWKTGRMVKRFTGHEREITKIACIPKANQFFSASRDKTVLMWDLQGSSHPRQQLSGHAMVVTGLAVSPDSSQLCTGSRDNSLLLWDVGTGQCVERASVSRNLVTHLCWVPSEPYIVQTSEDKTIRLWDSRGLQMAHMFPTKQHIQTHCEVSVDGHTCISCSSGFGGEGCEATLWDLRQTRDRMCEYKGHFQTVASCVFLPKSTALMPMIATSAHDSKVKIWNQDTGACLSTLSLDGSGPLTSLAVGDISSLLCASFYRGVHLLRVDHSQGLELQEVAAF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NA23-1", "uniprot_id": "WDR31_HUMAN", "id": "Q8NA23-1", "name": "WD repeat-containing protein 31", "aln": "MLLLRCQLKQAPPQKVSFRFCVVMGKQQSKLKHSTYKYGRPDEIIEERIQTKAFQEYSPAHMDTVSVVAALNSDLCVSGGKDKTVVAYNWKTGNVVKRFKGHEHEITKVACIPKSSQFFSASRDRMVMMWDLHGSSQPRQQLCGHAMVVTGLAVSPDSSQLCTGSRDNTLLLWDVVTGQSVERASVSRNVVTHLCWVPREPYILQTSEDKTLRLWDSRGLQVAHMFPAKQHIQTYCEVSVDGHKCISCSNGFGGEGCEATLWDLRQTRNRICEYKGHFQTVASCVFLPRALALMPLIATSSHDCKVKIWNQDTGACLFTLSLDGSGPLTSLAVGDAISLLCASFNRGIHLLRMDHSQGLELQEVAAF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BC93-1", "uniprot_id": "A0A8M2BC93_DANRE", "id": "A0A8M2BC93-1", "name": "", "aln": "-----------------------MGKLQSKFRRRSDLYKAKEG--AEPAPVHQVVQYEPAHTDAINCVVSLTSDLCVSGGHDQAVVVYDWRAGRLCKSFQGHNREITKLCCFKGSSLIFSASRDKTVLMWDLGRDTEAIQEFSGHELVVNGVAVSPDGSKLCTGSRDNSMCLWDIESGECLQRNTISRNLVTHVCWVPGSTSIVQTSEDKTIRVWDSRTWQVTNTFPAKQYIQTHCDVNANCYHLLSSSNGFGGQGCEATLWDLRQPGCKVAEYRGHLQTTACCVFVPTRPGCPALVASSSYDSSVKIWDQNTAACLYTLTLDGSGPLVSLAPCDSSSLLCASFNTGLHQLHLDQSAVPSITEVARF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *** ***:: : * : * .: :* *.* *::. :.:*.****:***:*::.*.*:*::*.: : * **::****:.*: :. :******: *:**** .:.. *::.** :**.*:*****.*:********:: ***: :*:.::* ::***:***:**** .. *:*******:*:**.* *::: **:**:***:*:*..: : :*.*.****:***********. ::.**:**:**.*.***:* . .::*:*::*..****:*:*.*** **:*******.*** * ******* *:* *::*:* .: *** *", "identical_positions": 170, "similar_positions": 111, "identity": "46.32%" } ]