bgsl_id term exact_synonyms abbreviations broad_synonyms narrow_synonyms related_synonyms classification gtc_id gsd_id glycomotif_id sources description eog_sentence hidden bGSL:609b6afe-8835-44cd-b7b3-501d6996b478 2-6 sialylparagloboside S2-6PG; 6'-LM1 Sialylparagloboside 1A G83513YI GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:02b3feeb-ecb2-4e39-897d-26a3cb0f99f9 2-fucosyl GD1b disialylated fucosylated glycan; GD1b; fucosylated glycan 1A G67383AR; G93694YU GSD:00002 GlycoMotif:GGM.000103; GlycoMotif:CCRC.000103; GlycoMotif:GDV.000010 GSD_GLYGEN_V1; CUMMINGS; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF (2S,4S,5R,6R)-5-Acetamido-6-[(1S,2R)-2-[(2S,4S,5R,6R)-5-acetamido-2-carboxy-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxan-2-yl]oxy-1,3-dihydroxypropyl]-2-[(2R,3S,4R,5R,6S)-3-[(2S,3R,4R,5R,6R)-3-acetamido-4-[(2R,3R,4S,5R,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-5-hydroxy-2-(hydroxymethyl)-6-[(2R,3S,4R,5R)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxan-4-yl]oxy-4-hydroxyoxane-2-carboxylic acid.[CHEBI:156680] They were fucosyl-Gv., fucoSyl-GDlb, and two uni que fucogangliosides having GMl or GOlb bas ic structure containing a substituent with the blood group B determinant. [PMID:3654655] bGSL:68b3bde9-8bc7-4204-9f35-b68e17c60f7e 2-fucosyl GM1 Fucosyl GM1 1A G56526JU; G91532KA GSD:00003 GlycoMotif:GGM.000101; GlycoMotif:CCRC.000101; GlycoMotif:GDV.000009 GSD_GLYGEN_V1; CUMMINGS; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF (2S,4S,5R,6R)-5-Acetamido-2-[(2R,3S,4R,5R,6S)-3-[(2S,3R,4R,5R,6R)-3-acetamido-4-[(2R,3R,4S,5R,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-5-hydroxy-2-(hydroxymethyl)-6-[(2R,3S,4R,5R)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxan-4-yl]oxy-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid.[CHEBI:151476] These glycolipid products were identified as asialo-Gs.., GM h and fucosyl-Gq, by comparison with authentic glycolipid samples.[PMID:3654655] bGSL:472b3ec0-b778-44eb-9ff2-931a2d88c40f 3'-KDN-Lewis c 3'-deaminoneuraminyl-Lewis c; 3'-KDNLec 3'-KDNLec 1A PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV; BIOOLIGO bGSL:dffaf382-1d76-4867-a8c6-adb0600451b4 3'-sialyl-di-Lewis a 3'S-Di-LeA 1A PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV bGSL:f7d951ae-5722-426f-a0c6-5df098201831 3'-sialyl-di-Lewis c 3'S-Di-Lec 1A PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV bGSL:75be977c-df44-4229-8c26-63b347ac2c23 3'-sialyl-Lewis a - Lewis x 3'-sialyl-Lewis a-Lewis x 3'SLeA-LeX 1A PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV bGSL:18e5bfd9-8fb3-45a8-a5e8-e2f0873b856e 3'-sialyl-Lewis c 3'SLec 3'-sialyl-Lewis c (Neu5Gc) 1A PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV; BIOOLIGO bGSL:0b4283df-4cd1-4f9e-bd63-7699d147efb6 3'-sialyl-Lewis c (Neu5Gc) 3'-N-glycolylneuraminyl-Lewis c 3'SLec (Gc) 3'-sialyl-Lewis c 1A PUBDICT_GLYCONAVI_NAME bGSL:ef1699bf-d666-41ce-af46-6ea89f5fad9f 3'-sialyl-Lewis x 3'SLex 1A PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV bGSL:623f3364-b257-4f01-9eb7-dc29c39479fd 3'-sialyllactose (Neu5Gc) 3'-N-glycolylneuraminyllactose 3'SL (Gc) 1A PUBDICT_GLYCONAVI_NAME bGSL:c3c9d691-a1e1-4c2b-82ea-2602e85c8c50 3'-sulfo Lewis a 3'-Sulfo Lewis a; 3'-Sulfo Lea; 3'-Sulfo Le^a; 3-sulfo Lewis a; 3'-sulfo Lewis a 3'-suLe^a; 3'-sulfo Lea; 3'-su-Lea 1A G78706CK; G36845IZ; G14395NH GSD:00005 GlycoMotif:GGM.000030; GlycoMotif:CCRC.000030; GlycoMotif:GDV.000047 GSD_GLYGEN_V1; CUMMINGS; GLYCOEPITOPE; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; BIOOLIGO A branched amino trisaccharide consisting of N-acetylglucosamine having a fucosyl residue attached at the 4-position via an α-linkage and a 3-sulfated galactosyl residue attached at the 3-position via a β-linkage.[CHEBI:65149] A remodeling system of the 3'-sulfo-Lewis a and 3'-sulfo-Lewis x epitopes.[PMID:11504739] bGSL:e935e93f-f5d4-4697-8f09-96ccff81c844 3'-sulfo Lewis x 3-sulfo Lewis x 3'-suLe^x; 3'-sulfo Lex; 3'-su-Lex Sulfo Lewis X; Lewis x 3Su-Gal-4(Fuc)-GlcNAc 1A G12295TB; G26555CS; G51907PX GSD:00006 GlycoMotif:GGM.000029; GlycoMotif:CCRC.000029; GlycoMotif:GDV.000048 GSD_GLYGEN_V1; CUMMINGS; GLYCOEPITOPE; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; BIOOLIGO An amino trisaccharide that consists of N-acetyl-β-D-glucosamine having an α-L-fucosyl residue attached at position 3 and a 3-sulfated β-D-galactosyl residue attached at position 4; β-D-Galp3S-(1→4)-[α-L-Fucp-(1→3)]-D-GlcpNAc in which the configuration at the anomeric centre of the reducing-end residue is β. [CHEBI:65171] A remodeling system of the 3'-sulfo-Lewis a and 3'-sulfo-Lewis x epitopes.[PMID:11504739] bGSL:556c2776-2053-4947-9369-2f6d916c8594 3,6-(LacNAc)2Tn 3,6-di-N-acetyllactosaminyl-Tn antigen 3-LacNAc-Tn 1A BIOOLIGO bGSL:72441dfc-fcc5-4d64-aedc-9fea1cbfa76c 3-6-STn disialyl Tn 1A BIOOLIGO bGSL:6fb8130b-b897-43f5-b989-926e598decb3 3-fucosyllactose 3-FL 1A BIOOLIGO bGSL:a7692cfb-a47b-4ffe-a987-50fe92d992b8 3-LacNAc-Tn 3-N-acetyllactosaminyl-Tn antigen 3,6-(LacNAc)2Tn 1A BIOOLIGO bGSL:4407138c-8058-4a3d-81e7-6517ce48d721 4'-sulfo-Lewis x Sulfo Lewis X 1A BIOOLIGO bGSL:1b9dbe4d-73de-49c7-b2e0-ee8015043901 6'-sialyl-T antigen 6'-SiaalphaTF 6'STF 1A PUBDICT_GLYCONAVI_NAME; BIOOLIGO bGSL:48f0a6ce-2971-4dec-a69b-095c6d861694 6'-sulfo-sialyl-Lewis x sialyl-6'-sulfo-Lex; Sialyl-6'-sulfo-Lewis x; 6'-sulfo-SLex; 6'-Sulfo Sialyl Lewis x; 6'-sulfo SLex; 6'-sulfo SLe^x 6'-sulfo-sLe(x); 6'-sulfo SLex 1A G00672PE; G77659VW; G06378CG GSD:00161 GlycoMotif:GGM.000025; GlycoMotif:CCRC.000025 GSD_GLYGEN_V1; EOG_VARKI_4E; CUMMINGS; GLYCOEPITOPE; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE A branched amino tetrasaccharide comprised of a trisaccharide chain of N-acetyl-α-neuraminic acid, 6-O-sulfo-β-D-glactose and N-acetyl-β-D-glucosamine residues linked sequentially (2→3) and (1→4), to the GlcNAC residue of which is also linked (1→3) an α-L-fucose residue.[CHEBI:71558] Studies using sulfotransferase-deficient mice showed that 6-sulfo sialyl Lewis X (6-sulfo sLe(x)), a major ligand for L-selectin that is expressed on the high endothelial venules (HEVs), plays critical roles in lymphocyte homing to the peripheral lymph nodes.[PMID:2288521] bGSL:fb5c872c-d0b9-4fca-8050-dfb014cb7da5 6,6'-dissulfo sialyl Lewis X 6,6'-bissulfo sialyl Lewis X sialyl Lewis x; 6-sulfo-sialyl-Lewis x; 6-sulfo-Lewis x 1A G00659GQ GSD:00007 GlycoMotif:GGM.000028 GSD_GLYGEN_V1; GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE (2S,4S,5R,6R)-5-Acetamido-2-[(2S,3R,4S,5S,6R)-2-[(2R,3S,4R,5R,6R)-5-acetamido-6-hydroxy-2-(sulfooxymethyl)-4-[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl]oxy-3,5-dihydroxy-6-(sulfooxymethyl)oxan-4-yl]oxy-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid.[CHEBI:146095] Comparison of the reactivity pattern of HEV with the reactivity of the pure 6-sulfo, 6'-sulfo, or 6,6'-bissulfo sialyl Lewis X determinant with hitherto known anti-sialyl Lewis X antibodies strongly suggested 6-sulfo sialyl Lewis X to be the best candidate for the major sulfated sialyl Lewis X determinant on HEV, followed by 6,6'-bissulfo sialyl Lewis X, whereas 6'-sulfo sialyl Lewis X was unlikely. [PMID:9556613] bGSL:7c9a622e-22b5-4fe6-90f0-48d576326960 6,6'-disulfo-Lewis x 6,6'-bissulfo Lex; 6,6'-Disulfo Sialyl Lewis x; 6,6'-bissulfo Le^x 6-sulfo-Lewis x 1A G00659GQ; G46799JK; G23094GH GlycoMotif:GGM.000028; GlycoMotif:CCRC.000028; GlycoMotif:GDV.000087 CUMMINGS; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF bGSL:9393ffb9-f722-4ccd-8c1c-416936adcc4f 6-LacNAc-T antigen 6-N-acetyllactosaminyl-T antigen; 6-LacNAc-TF 1A BIOOLIGO bGSL:698f7350-69f9-4003-bdca-a60baab7193d 6-LacNAc-Tn antigen 6-N-acetyllactosaminyl-Tn antigen; 6-LacNAc-Tn 1A BIOOLIGO bGSL:4ff40276-64ef-4d2b-9f3d-da022866ed15 6-Siab-TF 6-Sia-beta-TF; 6-beta-sialyl-T antigen 1A BIOOLIGO bGSL:ce5d1cbe-6d46-4bf2-b296-673e9166a16c 6-sialyl-LacNAc-Lewis c 6-sialyl-N-acetyllactosamine-Lewis c 6SLN-Lec 1A PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV bGSL:d17b1838-e1d1-4ca7-b154-e23c000e98b5 6-sulfo-galactosyl-sialyl-Lewis x 6-su-Gal-SiaLewis x 1A BIOOLIGO bGSL:129e6695-2aa6-4ab8-92a1-c461f35139c4 6-sulfo-Lewis x Sulfo Lewis X; Lewis x 6,6'-disulfo-Lewis x; 6,6'-dissulfo sialyl Lewis X; 6-sulfo-sialyl-Lewis x; cyclic sialyl 6-sulfo Lewis x 1A G89307GT GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:be96679e-ac35-4eee-941f-f77af446cf58 6-sulfo-sialyl-Lewis c Su-SaiLec Su-SaiLec; Su-SLec 1A G93779QZ SUGARBIND; PUBDICT_GLYCAN_MOTIF bGSL:b4ff339c-9808-4432-b504-0e7c2fe6ad56 6-sulfo-sialyl-Lewis x 6-Sulfo Sialyl Lewis x; 6-sulfo SLex; 6-sulfo SLe^x 6-sulfo SLex; 6-sulfo SLe^x; 6-sulfo SLewis x sialyl Lewis x; 6-sulfo-Lewis x 6,6'-dissulfo sialyl Lewis X; cyclic sialyl 6-sulfo Lewis x 1A G80722US; G23322RK; G00672PE; G53231FE GSD:00160 GlycoMotif:GGM.000027; GlycoMotif:CCRC.000027; GlycoMotif:GDV.000088; GlycoMotif:GDV.000104 GSD_GLYGEN_V1; EOG_VARKI_4E; CUMMINGS; GLYCOEPITOPE; SUGARBIND; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; BIOOLIGO 6-sulfo-sialyl Lewis X (6-sulfo-SLex) is a sialyl Lewis X (LeX) glycan motif that is further modified by sulfation at the 6-position of the N-acetylglucosamine. As a high-affinity L-selectin ligand (often on mucin-type glycoconjugates), it promotes leukocyte rolling and homing at high endothelial venules and can influence cell–cell interactions in inflammation and cancer.) The cognate ligands for L-selectin possess the unusual sulfated tetrasaccharide epitope 6-sulfo sialyl Lewis x (Siaalpha2-->3Galbeta1-->4[Fucalpha1-->3][SO(3)-->6]GlcNAc).[PMID:11331001] bGSL:21e8fa68-0dde-4b8c-936e-07ee7bfdbd55 9-O-acetyl GD3 9-O-Ac-GD3 acGD3 GD3; O-acetyl-GD3 1A G74121RX; G98544DH; G81928IQ GSD:00009 GlycoMotif:GGM.000093; GlycoMotif:CCRC.000093 GSD_GLYGEN_V1; CUMMINGS; GLYCOEPITOPE; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE To determine whether 9-O-acetyl GD3 (acGD3) has a general antiapoptotic potential, the apoptosis-sensitive Jurkat cell line and an apoptosis-sensitive variant of the cell line Molt-4 were preincubated with micromolar concentrations of acGD3 and then treated with inducers of apoptosis.[PMID:16432837] bGSL:8319b9e3-05b6-4d4a-b396-d9264ca6603a 9-O-acetyl-3'-sialyl-Lewis c 9OAc3'Slec 1A PUBDICT_GLYCONAVI_NAME bGSL:179e17ff-9724-45ac-a980-61d6c198439f a-Galactose on Core 2 alpha-Gal-core 2 O-glycan core 2 1A BIOOLIGO bGSL:6546673e-fe36-4044-89bc-b1e09f98ee74 a2-3 Neu5Ac on Core 1 Neu5Ac(a2-8)Neu5Ac(a2-3)Gal(b1-3)GalNAc 1A BIOOLIGO bGSL:d95af285-4bb2-496f-aa24-6680076754df acharan sulfate 1A G25575JK GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:ffb3839a-c88e-4547-b8a2-80ba92a7592d alkylacylphosphatidylinositol-anchored glycan 1A EOG_VARKI_4E A glycan structure that is attached to a membrane through an alkylacylphosphatidylinositol anchor. This glycan may contain components such as nonacetylated glucosamine, mannose, galactofuranose, and 2-aminoethylphosphonate. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch43/#:~:text=For%20T.%20cruzi%20sialylation%20is,of%20chemotherapeutic%20agents'] TRUE bGSL:e9f5bf6c-0f0a-4074-9565-80bbe3ca793a alpha-gal antigen a-Gal antigen; alpha-Gal antigen αGal Galalpha1-3Gal Galα1-3Galα; Galili antigen 1A G24432YB; G00046MO; G27798EJ GSD:00011 GlycoMotif:GGM.000015; GlycoMotif:CCRC.000015; GlycoMotif:GDV.000022 GSD_GLYGEN_V1; EOG_VARKI_4E; CUMMINGS; GLYCOEPITOPE; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE A glycosylgalactose that consists of β-D-galactose having an α-D-galactosyl residue at the 3-position.[CHEBI:62330] Therefore, alpha-gal antigen might be eliminated after a prolonged culture, when using human cells.[PMID:31267683] bGSL:8cca4a96-b002-4eeb-93b6-51797b669480 alpha-galactosylceramide alpha-GalCer; α-GalCer 1A GSD:00012 GSD_GLYGEN_V1 From 24 weeks of age, NZB/NZW F1 mice were injected with alpha-galactosylceramide (α-GalCer) or vehicle once a week for four weeks.[PMID:29844470] bGSL:87b9f818-cb60-4048-8a91-77b22ffbaa83 alpha-galactosylparagloboside A-galactosylparagloboside 1A G60645OK SUGARBIND; PUBDICT_GLYCAN_MOTIF bGSL:eb2fbd90-ce39-4a40-89de-e9ff7e9b0260 asialo-GM1 Asialo-GM1a aGM1 Gg4 1A G21856LC; G00407UJ GSD:00014; GSD:00174 GlycoMotif:GGM.000099; GlycoMotif:CCRC.000099; GlycoMotif:GDV.000033 GSD_GLYGEN_V1; EOG_VARKI_4E; CUMMINGS; GLYCOEPITOPE; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV; BIOOLIGO Gg4 (gangliotetraosylceramide) is a glycosphingolipid, specifically a ganglioside, consisting of a ceramide backbone attached to a tetrasaccharide chain. It belongs to the globo-series of glycolipids. bGSL:d76c2a86-3212-491b-80fc-c1045404d278 B-GD1b blood group B-GD1b GD1b 1A G72557NR; G29966WK GlycoMotif:GGM.000104; GlycoMotif:CCRC.000104; GlycoMotif:GDV.000019 CUMMINGS; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF bGSL:42a21b77-d6af-499b-9a8c-122b4068dec1 B-GM1 blood group B-GM1 GM1b 1A G11485ID; G03277YI; G14633CL; G46884IT GSD:00015; GSD:00172 GlycoMotif:GGM.000102; GlycoMotif:GGM.000100; GlycoMotif:CCRC.000100; GlycoMotif:CCRC.000102; GlycoMotif:GDV.000018; GlycoMotif:GDV.000102 GSD_GLYGEN_V1; CUMMINGS; SUGARBIND; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF (2S,4S,5R,6R)-5-Acetamido-2-[(2R,3S,4R,5R,6S)-3-[(2S,3R,4R,5R,6R)-3-acetamido-5-hydroxy-4-[(2R,3R,4S,5S,6R)-5-hydroxy-6-(hydroxymethyl)-4-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-6-(hydroxymethyl)oxan-2-yl]oxy-5-hydroxy-2-(hydroxymethyl)-6-[(2R,3S,4R,5R,6R)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxan-4-yl]oxy-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid is a member of neuraminic acids.[CHEBI:147588] The contribution of GM3 and GD3, which accounted for 95% of the ganglioside sialic acid at birth, decreased during the first 3 weeks of life. GM1, fucosyl-GM1, and B-GM1 were not detected at birth. [PMID: 3680254] bGSL:e579c82b-3d5c-4ad8-8d8f-f9458b6d4ce4 beta-galactosylated core 2 b-galactosylated Core 2 O-glycan core 2 1A BIOOLIGO bGSL:5a677813-a71b-4f27-ad7f-0d53e15967e8 blood group A A blood group determinant; Antigen A; Blood group A determinant; Blood Group A Trisaccharide; A antigen(tri-); blood group A determinant Blood group A pentaose type 2; blood group A type 3; Blood group A1; Blood group A2; Blood group A - Lewis b; blood group A type 1; blood group A type 4; blood group A type 2; blood group A type 6 1A G00066MO; G55958KV GSD:00018 GlycoMotif:CCRC.000038; GlycoMotif:CCRC.000039; GlycoMotif:CCRC.000044; GlycoMotif:CCRC.000047; GlycoMotif:CCRC.000088 GSD_GLYGEN_V1; EOG_VARKI_4E; GLYCOMOTIF_CCRC; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; PUBDICT_MOTIF_GTC; SUGARBIND; GLYCOEPITOPE; BIOOLIGO A branched amino trisaccharide consisting of β-D-galactose having an α-L-fucosyl residue at the 2-position and an N-acetyl-α-D-galactosaminyl residue at the 3-position.[CHEBI:61012] A readily detectable carbohydrate in the urine of two siblings with neuronal ceroid lipofuscinosis was found to be the blood group A trisaccharide.[PMID:7249368] bGSL:18e2d33b-dd4e-4b9b-8407-98d4b49e21f3 Blood group A - Lewis b Blood group A - Lewis b-associated type 1 chain; Blood group A (type 1) - Lewis b A Leb; A type 1 A Leb; A-Le^b blood group A; blood group A type 1 1A G48600JD; G12068BR; G97501MA GlycoMotif:GGM.000047; GlycoMotif:GDV.000054 SUGARBIND; GLYCOMOTIF_GGM; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; BIOOLIGO; CUMMINGS; GLYCOEPITOPE; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:03db1d4e-1f02-4805-bbe1-241a031df7b9 blood group A - Lewis y Blood group A - Lewis y associated type 2 chain; 2'F-A type 2; blood group A (type 2) - Lewis y A-Ley; A-Le^y blood group A type 2 1A G54826OZ GlycoMotif:GGM.000039; GlycoMotif:GDV.000059 CUMMINGS; GLYCOEPITOPE; GLYCOMOTIF_GGM; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; BIOOLIGO; PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV bGSL:415e3681-ac5d-4816-ac05-a8d7d4eca5f7 blood group A heptaose type 1 blood group A type 1 1A G71485PH SUGARBIND An α-D-GalpNAc-(1→3)-[α-L-Fucp-(1→2)]-β-D-Galp-(1→3)-D-GlcpNAc having β-configuration at the reducing end anomeric centre.[CHEBI:62485] TRUE bGSL:995e6057-8093-40fa-9672-b2dc4811b2b5 Blood group A hexaose type 1 Blood group A antigen hexaose type 1; blood group A hexaose type 1 [sb] blood group A type 1 1A G82858KU BIOOLIGO; SUGARBIND TRUE bGSL:87669430-d983-46a9-8a07-b0f142483592 Blood group A hexaose type 2 Blood group A antigen hexaose type 2 blood group A type 2 1A BIOOLIGO TRUE bGSL:f84f760b-a9eb-4903-b574-0662e0f19c83 blood group A nonaose type 1 blood group A type 1 1A SUGARBIND An α-D-GalpNAc-(1→3)-[α-L-Fucp-(1→2)]-β-D-Galp-(1→3)-D-GlcpNAc having β-configuration at the reducing end anomeric centre.[CHEBI:62485] TRUE bGSL:312c5dc6-fbcd-4792-8488-d5a9dfe056b7 blood group A octaose type 1 blood group A type 1 1A G04715SK SUGARBIND An α-D-GalpNAc-(1→3)-[α-L-Fucp-(1→2)]-β-D-Galp-(1→3)-D-GlcpNAc having β-configuration at the reducing end anomeric centre.[CHEBI:62485] TRUE bGSL:44cfc758-c268-49f1-97e4-038bf97887ff Blood group A pentaose type 1 Blood group A antigen pentaose type 1 blood group A type 1 1A BIOOLIGO TRUE bGSL:953035a3-e679-451a-8334-d3d3875cf4ee Blood group A pentaose type 2 Blood group A antigen pentaose type 2 blood group A; blood group A type 2 1A BIOOLIGO TRUE bGSL:e3de5f44-3b92-40cc-b57f-fdbd4402d973 Blood group A pentaose type 4 Blood group A antigen pentaose type 4 blood group A type 4 1A BIOOLIGO TRUE bGSL:ca32d0a4-6e98-4ced-85e8-ac60a53087ab blood group A type 1 A type 1; blood group A tetraose type 1; blood group A tetrasaccharide type 1 A tetra type 1 blood group A Blood group A - Lewis b; Blood group A hexaose type 1; blood group A heptaose type 1; blood group A nonaose type 1; blood group A octaose type 1; Blood group A pentaose type 1 1A G66163TI GSD:00019 GlycoMotif:GGM.000044; GlycoMotif:GDV.000058 GSD_GLYGEN_V1; CUMMINGS; GLYCOEPITOPE; GLYCOMOTIF_GGM; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; BIOOLIGO; PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV An α-D-GalpNAc-(1→3)-[α-L-Fucp-(1→2)]-β-D-Galp-(1→3)-D-GlcpNAc having β-configuration at the reducing end anomeric centre.[CHEBI:62485] bGSL:b64c3f8e-f226-41cc-989d-40a09a23988b blood group A type 2 A type 2; blood group A tetraose type 2; blood group A tetrasaccharide type 2 A-tetra type 2 blood group A Blood group A hexaose type 2; Blood group A pentaose type 2; blood group A - Lewis y 1A G74353FF; G17108EX GSD:00020 GlycoMotif:GGM.000038; GlycoMotif:GDV.000060 GSD_GLYGEN_V1; CUMMINGS; GLYCOEPITOPE; SUGARBIND; GLYCOMOTIF_GGM; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV; BIOOLIGO A branched amino tetrasaccharide comprising N-acetyl-β-D-glucosamine at the reducing end with a N-acetyl-α-D-galactosaminyl-(1→3)-[α-L-fucosyl-(1→2)]-β-D-galactosyl moiety attached at the 4-position.[CHEBI:62486] One hybridoma antibody (AH16), obtained on immunization with human gastric cancer cell MKN45, was directed to the blood group A determinant carried by both type 1 and type 2 chains. [PMID:6583282] bGSL:3dcc4c4d-3e9e-452c-84c2-e1f1b1d5bd19 blood group A type 3 A type 3; Blood group A (type 3); Blood group A type 3 blood group A Blood group A2; Blood group A1 1A G99315PE; G71832QJ GSD:00021 GlycoMotif:GGM.000011; GlycoMotif:GDV.000056; GlycoMotif:CCRC.000011 GSD_GLYGEN_V1; CUMMINGS; GLYCOEPITOPE; GLYCOMOTIF_GGM; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; GLYCOMOTIF_CCRC nan bGSL:f61ab951-488b-47a0-af32-d701eb38115b blood group A type 4 A type 4 ABH precursor chain type 4; blood group A Blood group A pentaose type 4; Globo-A 1A G17480GI GSD:00022 GlycoMotif:GGM.000088; GlycoMotif:GDV.000057 GSD_GLYGEN_V1; CUMMINGS; GLYCOEPITOPE; GLYCOMOTIF_GGM; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:2dd84bf0-d355-42c4-b47c-8564fd62a1f0 blood group A type 6 blood group A - lactose; A-tetra Lactose; blood group A tetraose - lactose; blood group A tetraose type 6 A tetra L blood group A 1A PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV; BIOOLIGO bGSL:9dae8754-3e97-4538-9d36-ff2c7fed71fd Blood group A1 Blood group A1 - type 3 chain blood group A; blood group A type 3 1A G03986GH; G44060QH GlycoMotif:CCRC.000040; GlycoMotif:GGM.000040; GlycoMotif:GDV.000055 GLYCOMOTIF_CCRC; PUBDICT_GLYCAN_MOTIF; CUMMINGS; GLYCOMOTIF_GGM; GLYCOMOTIF_GDV bGSL:364ea25b-c59f-474e-8e24-6f102d4b679f Blood group A2 Blood group A2 - A-associated H type 3 chain blood group A type 3; blood group A 1A G19804SF; G62735WZ GlycoMotif:CCRC.000041; GlycoMotif:GGM.000041; GlycoMotif:GDV.000005 GLYCOMOTIF_CCRC; PUBDICT_GLYCAN_MOTIF; CUMMINGS; GLYCOMOTIF_GGM; GLYCOMOTIF_GDV bGSL:33ea7d4d-82c8-47df-88bf-85323775fd1c blood group B B blood group determinant; Blood group B antigen triose; blood group B determinant blood group B type 4; blood group B type 2; blood group B type 1; blood group B type 6; blood group B - Lewis b 1A G00067MO; G58612ZQ GlycoMotif:CCRC.000037; GlycoMotif:CCRC.000043; GlycoMotif:CCRC.000046; GlycoMotif:CCRC.000087; GlycoMotif:GGM.000201 EOG_VARKI_4E; GLYCOMOTIF_CCRC; PUBDICT_GLYCAN_MOTIF; PUBDICT_MOTIF_GTC; SUGARBIND; GLYCOMOTIF_GGM; BIOOLIGO The blood group B determinant is a specific glycan epitope, typically Galα1-3(Fucα1-2)Gal-R, present on the surface of red blood cells, glycoproteins, and glycolipids. It defines the blood group B antigen in humans and is formed by the terminal addition of galactose to the H antigen, catalyzed by B-transferase. This structure is recognized by specific antibodies and lectins, and is a key determinant in blood group typing. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch57/#:~:text=GMI-1070%2C%20targeting%20E-%2C%20P-%2C%20and,into%20%E2%80%9Cuniversal%20donor%E2%80%9D%20O%20red%20cells', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch57/#:~:text=GMI-1070%2C%20targeting%20E-%2C%20P-%2C%20and,into%20%E2%80%9Cuniversal%20donor%E2%80%9D%20O%20red%20cells'] ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch36/#:~:text=Galectin-1%20directly%20binds%20to,immune%20responses%20against%20pathogens'] ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch14/#:~:text=Similarly%2C%20blood%20group%20B,death%20from%20circulatory%20collapse'] ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch36/#:~:text=Galectins%20can%20also%20bind%20to,in%20the%20cytoplasm%20before%20secretion'] bGSL:350eaf37-b6db-4df2-be31-7400c918ee7c blood group B - Lewis b Blood group B - Lewis y-associated type 1 chain; blood group B (type 1) - Lewis b; B7 type 1 (B Lewis b(7)) B Leb; B type 1 B Leb; B Lewis b; B-Le^b Blood group B pentaose type 1; blood group B; blood group B type 1 1A G60395SO; G94938PL; G89208KM; G22689CV GlycoMotif:GGM.000046; GlycoMotif:GDV.000016 SUGARBIND; GLYCOMOTIF_GGM; PUBDICT_GLYCAN_MOTIF; BIOOLIGO; CUMMINGS; GLYCOMOTIF_GDV bGSL:9c5d628d-f44d-4953-a831-430be9a0dcf6 blood group B - Lewis y Blood group B Lewis Y antigen pentaose type2; blood group B (type 2) - Lewis y B-ley Blood group B pentaose type 2 1A BIOOLIGO bGSL:190731e0-1c92-441f-a333-a22f8bc9c23d Blood group B hexaose type 1 Blood group B antigen hexaose type 1; blood group B hexaose type 1 [sb] blood group B type 1 1A G63238VS BIOOLIGO; SUGARBIND TRUE bGSL:8139ae10-6ba0-4a6c-a29e-57486fa44061 Blood group B hexaose type 2 Blood group B antigen hexaose type 2 blood group B type 2 1A BIOOLIGO TRUE bGSL:551ef931-ed8d-4e6d-88f2-5c26dda19139 Blood group B pentaose type 1 Blood group B antigen pentaose type 1 blood group B type 1 blood group B - Lewis b 1A BIOOLIGO TRUE bGSL:029ea146-1be9-4043-be3c-d02cc178f697 Blood group B pentaose type 2 Blood group B antigen pentaose type 2 blood group B type 2 blood group B - Lewis y 1A BIOOLIGO TRUE bGSL:006b4b21-bb43-4407-97ac-df55d8104a7a Blood group B pentaose type 4 Blood group B antigen pentaose type 4 blood group B type 4 1A BIOOLIGO TRUE bGSL:f771df44-f831-4c6b-8aec-30c6fcc55b08 blood group B type 1 B type 1; B tetra type 1; blood group B tetraose type 1 blood group B Blood group B pentaose type 1; Blood group B hexaose type 1; blood group B - Lewis b 1A G31734OS GSD:00023 GlycoMotif:GGM.000043; GlycoMotif:GDV.000020 GSD_GLYGEN_V1; CUMMINGS; GLYCOMOTIF_GGM; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV; BIOOLIGO α-D-Galp-(1→3)-[α-L-Fucp-(1→2)]-β-D-Galp-(1→3)-β-D-GlcpNAc with β configuration at the anomeric carbon of the GlcNAc residue at the reducing end.[CHEBI:63242] bGSL:71e4b84a-a04e-4b33-a595-094c069dfece blood group B type 2 B type 2; B-tetra type 2; blood group B tetraose type 2 blood group B Blood group B hexaose type 2; Blood group B pentaose type 2 1A G94956AW GSD:00024 GlycoMotif:GGM.000037; GlycoMotif:GDV.000021 GSD_GLYGEN_V1; CUMMINGS; GLYCOEPITOPE; GLYCOMOTIF_GGM; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV; BIOOLIGO The detection of a B type 2 determinant is the first chemical evidence for the presence of an autologous difucosyl blood group B type 2 antigen in human adenocarcinoma cells.[PMID:2432062] bGSL:56d827d3-77bf-4230-9f37-cfb78f5bda92 blood group B type 4 B type 4; blood group B tetraose type 4 ABH precursor chain type 4; blood group B Blood group B pentaose type 4 1A GSD:00025 GlycoMotif:GGM.000087; GlycoMotif:GDV.000017 GSD_GLYGEN_V1; CUMMINGS; GLYCOMOTIF_GGM; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF The blood group B type-4 heptaglycosylceramide is a minor blood group B structure in human B kidneys in contrast to the corresponding A type-4 compound in A kidneys.[PMID:1390942] bGSL:fc4aec70-4826-43ef-9500-b47cf156f98e blood group B type 6 B-tetra Lactose; blood group B - lactose; blood group B tetraose - lactose; blood group B tetraose type 6 B tetra L blood group B 1A BIOOLIGO; PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV bGSL:ff4b8c7c-2c85-41a3-a762-7c2777f9a33d blood group H H blood group determinant; Blood Group H Disaccharide; H antigen; blood group H determinant; blood group O determinant Internal Blood Group H; blood group H type 4; blood group H type 1; blood group H type 2; blood group H type 6; blood group H type 3 1A G00068MO; G66086EX GlycoMotif:CCRC.000036; GlycoMotif:CCRC.000042; GlycoMotif:CCRC.000045; GlycoMotif:CCRC.000010 EOG_VARKI_4E; GLYCOMOTIF_CCRC; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; PUBDICT_MOTIF_GTC; GLYCOEPITOPE; SUGARBIND The blood group H determinant is a glycan antigen and epitope characterized by the presence of an α1-2-linked fucose residue, synthesized by α1-2 fucosyltransferase (FucT). It is formed by the addition of α1-2-linked fucose to the terminal galactose of a type 1 unit (Galβ1-3GlcNAc), resulting in the structure Fucα1-2Galβ1-3GlcNAc. This determinant serves as a precursor for ABO blood group antigens. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch48/#:~:text=For%20the%20UDP-Gal%20transporter%20from,Lex%20and%20SLex%20%28for%20the%20%CE%B11-3%20FucT%29'] ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch14/#:~:text=The%20Lewis%20b%20antigen%20%28Leb%29%20is,same%20epithelia%20that%20express%20FUT2'] bGSL:7d6f9d1a-c3dd-4a58-b205-c8897def9f21 blood group H heptaose type 2 H3 blood group H type 2 1A PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV TRUE bGSL:71dba067-8ced-4663-8a6c-8173f23c9533 blood group H pentaose type 1 blood group H type 1 1A G00050MO SUGARBIND A core trisaccharide glycan structure with the sequence Fucα1-2Galβ1-3GlcNAc, characteristic of the type 1 blood group H antigen. This structure can serve as a core that may be further substituted or capped in various glycan contexts. TRUE bGSL:a50e5e3c-2446-4972-af64-bea9ab1eed1b Blood group H pentaose type 2 Blood group H antigen pentaose type 2; blood group H pentaose type 2 [gn] blood group H type 2 1A BIOOLIGO; PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV TRUE bGSL:c7aca49c-a2e1-48cb-a77d-5b406bf09ab9 Blood group H tetraose type 1 Blood group H antigen tetraose type 1 blood group H type 1 1A BIOOLIGO TRUE bGSL:ee8b1009-564d-497a-ae0a-bb9a7375f0a5 Blood group H tetraose type 2 Blood group H antigen tetraose type 2 blood group H type 2 1A BIOOLIGO TRUE bGSL:16e9a223-88a3-4397-b9f6-b8be9ee7ed2e Blood group H tetraose type 4 Blood group H antigen tetraose type 4 blood group H type 4 Gb4 1A BIOOLIGO TRUE bGSL:6839090e-d428-4325-81f8-01235612406d blood group H type 1 H type 1; type 1 blood group H core trisaccharide; blood group H triose type 1 H1 (tri-) blood group H blood group H pentaose type 1; Blood group H tetraose type 1 Lewis d 1A G88393MK; G40696TO GSD:00026 GlycoMotif:GGM.000042; GlycoMotif:GDV.000011 GSD_GLYGEN_V1; EOG_VARKI_4E; CUMMINGS; GLYCOEPITOPE; SUGARBIND; GLYCOMOTIF_GGM; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV; BIOOLIGO A core trisaccharide glycan structure with the sequence Fucα1-2Galβ1-3GlcNAc, characteristic of the type 1 blood group H antigen. This structure can serve as a core that may be further substituted or capped in various glycan contexts. bGSL:2e9ccf74-0647-4d47-ae03-7d07bd7cb40c blood group H type 2 Blood group H triaose type 2; Blood group H antigen triaose type 2; H type 2; blood group H triose type 2 H2 blood group H Blood group H tetraose type 2; Blood group H pentaose type 2; blood group H heptaose type 2; Lewis y 1A G61459JW GSD:00027 GlycoMotif:GGM.000036; GlycoMotif:GDV.000015 BIOOLIGO; GSD_GLYGEN_V1; CUMMINGS; GLYCOEPITOPE; GLYCOMOTIF_GGM; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV bGSL:5a242ad8-ac4e-43a0-b515-12ac6a092a95 blood group H type 3 H type 3; blood group H triose type 3 blood group H 1A G94435QH GSD:00028 GlycoMotif:GGM.000010; GlycoMotif:GDV.000006 GSD_GLYGEN_V1; CUMMINGS; GLYCOEPITOPE; GLYCOMOTIF_GGM; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; BIOOLIGO bGSL:d1046adc-3f9b-462d-8a2f-15e7de52b620 blood group H type 4 Blood group H antigen triose type 4; H type 4; blood group H triose type 4 ABH precursor chain type 4; blood group H Blood group H tetraose type 4; Globo-H 1A G35778AN GSD:00029 GlycoMotif:GGM.000086; GlycoMotif:GDV.000007 BIOOLIGO; GSD_GLYGEN_V1; CUMMINGS; GLYCOEPITOPE; GLYCOMOTIF_GGM; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE An amino hexasaccharide consisting of α-L-fucose, β-D-galactose, N-acetyl-α-D-galactosamine, α-D-galactose, β-D-galactose and β-D-glucose residues joined in sequence with (1→2)-, (1→3)-, (1→3)-, (1→4)- and (1→4)-linkages, respectively.[CHEBI:65245] bGSL:3beb7604-61a0-4033-96aa-269ecfd0fc44 blood group H type 6 blood group H triose type 6 blood group H 2'-fucosyllactose 1A BIOOLIGO bGSL:76ddd0a0-92c6-4385-89d7-14883e9ce8f9 CA19-9 carbohydrate antigen 19-9 sialyl Lewis a 1A G00053MO GSD:00178 GSD_GLYGEN_V1; EOG_VARKI_4E; PUBDICT_GLYCAN_MOTIF Related synonym extracted from gsdv1 edge. See edges.jsonl for the linked subject term. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch46/#:~:text=Some%20of%20these%20changes%20have%20been,consisting%20predominantly%20of%20mucins'] bGSL:92b2d38a-954b-41d6-808d-00bd4e946474 Cad antigen CAD; Cad blood group antigen 1A G00063MO PUBDICT_GLYCAN_MOTIF; PUBDICT_MOTIF_GTC bGSL:c7916b57-f869-4449-971e-835f2c9f2e09 CD77 Gb3 1A G00059MO GSD:00176 GSD_GLYGEN_V1; EOG_VARKI_4E Related synonym extracted from gsdv1 edge. See edges.jsonl for the linked subject term. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch47/#:~:text=Many%20%E2%80%9Ctumor-specific%E2%80%9D%20monoclonal,signaling%20by%20numerous%20receptors'] bGSL:0e05b26e-1b44-49e8-80ff-9d62f15dd070 ceramide trihexoside CTH; Trihexosylceramide Gb3 1A PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV Gb3, also known as the Pk antigen, is a type of glycosphingolipid containing a trisaccharide core structure with the sequence Galα1-4Galβ1-4Glc. It acts as a receptor for Shiga toxins. bGSL:01e14c41-6617-439e-9c3e-5a7443817c43 chondroitin chondroitin sulfate; chondroitin sulfate C; chondroitin sulfate A; Chondroitin tetrasaccharide 1A G43702JT; G00018MO EOG_VARKI_4E; GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; PUBDICT_MOTIF_GTC Chondroitin is a glycosaminoglycan composed of repeating disaccharide units of N-acetylgalactosamine and glucuronic acid. These units can be further modified by sulfation and epimerization. Chondroitin serves as the backbone for chondroitin sulfate and related structures. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch17/#:~:text=Vertebrates%20also%20express%20homologs,glucuronic%20acid%20to%20iduronic%20acid', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch21/#:~:text=However%2C%20some%20CPSs%20in%20important,members%20of%20the%20gut%20microbiota', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch22/#:~:text=Individual%20cells%20of%20Methanosarcina,of%20glucose%20and%20galactose%20acids', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch25/#:~:text=SQV-4%20and%20SQV-1%20proteins%20represent,the%20eggshell%20and%20the%20embryo', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch25/#:~:text=The%20requirement%20for%20chondroitin,chondroitin%20chains%20%28Figure%2025.6%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch28/#:~:text=GBPs%20%28which%20exclude,are%20evolutionarily%20unrelated'] bGSL:9c3cc7e2-a3c4-47ff-a756-0bd988341d82 chondroitin sulfate chondroitin sulphate CS chondroitin sulfate/dermatan sulfate; chondroitin chondroitin sulfate A 1A G00018MO GSD:00030 GSD_GLYGEN_V1; EOG_VARKI_4E; PUBDICT_MOTIF_GTC Any of a class of 10‚Äî60 kDa glycosaminoglycan sulfates, widely distributed in cartilage and other mammalian connective tissues.[CHEBI:37397] The industrial production of chondroitin sulfate (CS) uses animal tissue sources as raw material derived from different terrestrial or marine species of animals.[PMID: 31013685] bGSL:9a6da58f-44f0-4db0-9877-4d311aa283fb chondroitin sulfate A chondroitin 4-sulfate; chondroitin sulfate A CS-A chondroitin sulfate; chondroitin 1A G00018MO; G19059PI GSD:00179 GSD_GLYGEN_V1; EOG_VARKI_4E; GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE Related synonym extracted from gsdv1 edge. See edges.jsonl for the linked subject term. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch30/#:~:text=As%20with%20many%20complexes%20involving%20a,that%20make%20contact%20with%20a%20protein'] ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch17/#:~:text=Heparan%20%28more...%29%20Additional,exolytic%20activities%20%28Chapter%2044%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch43/#:~:text=Desialylation%20of%20erythrocytes,pathogenesis%20%28Chapter%2012%29.%20P'] bGSL:fd13f4ef-aef1-4632-941a-3548e028a33f chondroitin sulfate C CS-C chondroitin 1A G34992DF GSD:00181 GSD_GLYGEN_V1; EOG_VARKI_4E; GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE Related synonym extracted from gsdv1 edge. See edges.jsonl for the linked subject term. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch17/#:~:text=Heparan%20%28more...%29%20Additional,exolytic%20activities%20%28Chapter%2044%29'] bGSL:31b38f04-155d-43db-9c0c-8beeb8679c38 chondroitin sulfate D chondroitin 2,6-sulfate 1A G46732TY GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:9f54bea0-c7ef-4f78-a80c-5fefdc64edcc chondroitin sulfate/dermatan sulfate chondroitin/dermatan sulfate CS/DS chondroitin sulfate 1A GSD:00031 GSD_GLYGEN_V1 Heparan sulfate (HS) and chondroitin sulfate/dermatan sulfate (CS/DS) proteoglycans are heavily glycosylated proteins, crucial for animal development and homeostasis. [PMID:35192612] bGSL:9ed63f73-219e-4f04-a7b8-eb814ea1d81c cyclic sialyl 6-sulfo Lewis x 6-sulfo-sialyl-Lewis x; 6-sulfo-Lewis x 1A G11148DZ; G23322RK; G80722US; G53231FE GSD:00157 GlycoMotif:CCRC.000023; GlycoMotif:GDV.000001 GSD_GLYGEN_V1; CUMMINGS; GLYCOEPITOPE; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE Stimulation of the sialyl 6-sulfo Lewis X-positive colon cancer cell line with a calcium ionophore ionomycin markedly reduced sialyl 6-sulfo Lewis X and induced cyclic sialyl 6-sulfo Lewis X expression.[PMID:10728707] bGSL:edbbb3fa-cc57-54d4-a3ff-ca7528de0365 cytolipin K Gb4 1A G00061MO GSD:00071 GlycoMotif:GGM.000070 GSD_GLYGEN_V1 An amino tetrasaccharide consisting of 2-acetamido-2-deoxy-β-D-galactopyranosyl, α-D-galactopyranosyl, β-D-galactopyranosyl, and β-D-glucopyranose units joined together in sequence by (1→3), (1→4), and (1→4) glycosidic linkages, respectively.[CHEBI:145578] Here we report that PUGNAc treatment provokes globotetraosylceramide (Gb4Cer) accumulation in human umbilical vein endothelial cells (HUVEC).[PMID:28392398] bGSL:78457f8b-4b4a-4689-b250-69515fb326ea Cytolipin R Forssman antigen; iGb4 1A G57710SU; G19926LY GSD:00040 GlycoMotif:GGM.000083; GlycoMotif:CCRC.000083; GlycoMotif:GDV.000063 GSD_GLYGEN_V1; CUMMINGS; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF A ceramide tetrahexoside isolated from rat lymphosarcoma. The structure of cytolipin R to be N-acetylgalactosaminyl(beta1-->3)galactosyl(alpha1-->3) galactosyl(beta1-->4)glucosyl ceramide.[PMID:5068000] The reaction can be inhibited completely by pure cytolipin R showing that (a) immune hemolysis can be mediated through lipid determinants in the membrane, and (b) that cytolipin R determinants are present in the intact erythrocyte membrane and exposed on the surface.[PMID:4110375] bGSL:f9dd8a38-31fe-4af9-a52c-ecca42f59a06 delta-heparan sulfate 1A G17927IW GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:11cd6fb7-08ce-4ccc-9080-50b09f22cd97 dermatan sulfate beta-Heparin CS-B 1A G00019MO GSD:00041; GSD:00180 GSD_GLYGEN_V1; EOG_VARKI_4E; PUBDICT_GLYCAN_MOTIF; PUBDICT_MOTIF_GTC Any of a group of glycosaminoglycans with repeating units consisting of variously sulfated β1→4-linked L-iduronyl-(α1→3)-N-acetyl-D-galactosamine units.[CHEBI:18376] By utilizing sophisticated separation methods followed by compositional analysis, domain mapping, and tandem mass spectrometry coupled with analysis by a modified genetic algorithm approach, the structural motif for the decorin dermatan sulfate chain was determined.[PMID:29111696] bGSL:263b82e5-fc0d-4fdc-a292-f8a013badada di-Lewis a Dimeric Lea; dimeric Lewis a Di-LeA 1A G06148DR; G82106UN; G21808VY GlycoMotif:CCRC.000126; GlycoMotif:GDV.000025 CUMMINGS; GLYCOEPITOPE; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV bGSL:2ad7dc83-6681-47a3-b245-b9cd25c04de1 di-Lewis c Di-Lec 1A PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV bGSL:a4e9fd74-80a7-46f9-8c82-82819729c21f di-Lewis x dimeric Le(x); Lex-Lex; Le^x-Le^x; dimeric Lewis x DimLex^x; diLe(x) Lewis x (Lex-6) 1A G79535HZ; G45673KX GSD:00044 GlycoMotif:GGM.000031; GlycoMotif:CCRC.000031; GlycoMotif:GDV.000037 GSD_GLYGEN_V1; CUMMINGS; GLYCOEPITOPE; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV; BIOOLIGO A six-membered glucosamine oligosaccharide consisting of two repeating units of β-D-Gal-(1→4)-[α-L-Fuc-(1→3)]-β-D-GlcNAc joined by a (1→3)-linkage.[CHEBI:61325] The carbohydrate antigen dimeric Lewis X (DimLex), which accumulates in colonic and liver adenocarcinomas, is a valuable target to develop anti-cancer therapeutics.[PMID:32957489] bGSL:ed915b49-3012-5ee1-9b61-b31b63d9a55f Disialogangliotetraosylceramide GD1b; GD1a-alpha 1A G37184KW; G46677TE PUBDICT_GLYCAN_MOTIF bGSL:59f6ac13-ecc6-4c7d-8d76-bcae5f87cf10 disialosyl globopentaosylceramide Disialosyl Gb5 DSGb5; DSGG sialopentaosylceramide; Disialosylpentaose; Gb5 1A G97932OH; G75814EP GSD:00046; GSD:00162 GlycoMotif:GGM.000082; GlycoMotif:CCRC.000082; GlycoMotif:GDV.000093 GSD_GLYGEN_V1; CUMMINGS; GLYCOEPITOPE; SUGARBIND; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE Disialosyl globopentaosylceramide (DSGb5) is a ganglioside originally isolated from tissue extracts of renal cell carcinoma (RCC) with metastasis.[PMID:28205070] Disialosyl globopentaosylceramide (DSGb5) is often expressed by renal cell carcinomas.[PMID:31339142] bGSL:68e3469c-9f69-493a-a8e2-c4ab06f38f6c disialyl Core 2 O-glycan core 2 disialyl Core 2 with sLex on Core 2 1A BIOOLIGO bGSL:e29a094b-29f6-4f5a-ac58-109c2e766f8a disialyl Core 2 with sLex on Core 2 disialyl Core 2; SLex on Core 2 O-glycan 1A BIOOLIGO bGSL:1dc3e797-48c7-403c-a98a-c9f7e77e2616 disialyl I antigen disialyl I I antigen 1A G54937EM GSD:00167 GSD_GLYGEN_V1; GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE "Here we present an example of promotion of binding of soluble-form FN from placenta or from hepatoma cells, having a specific carbohydrate epitope termed ""disialyl-I,"" to K562 or VA13 cell surface in the presence of glycosphingolipid Gg3, which interacts specifically with disialyl-I[PMID:10640401]" bGSL:c2549508-6867-413b-83e5-73777f0086a3 disialyl T antigen disialyl-T; disialylated T-antigen T antigen 1A G01614ZM; G65191ST; G84906ML GSD:00048 GlycoMotif:GGM.000014; GlycoMotif:CCRC.000014; GlycoMotif:GDV.000092 GSD_GLYGEN_V1; CUMMINGS; GLYCOEPITOPE; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE α-Neup5Ac-(2→6)-[α-Neup5Ac-(2→3)-β-D-Galp-(1→3)]-α-D-GalpNAc in which the anomeric configuration of the reducing-end N-acetyl-D-glucosamine residue is α.[CHEBI:71602] The most potent glycoside was disialyl T antigen (NeuAcalpha2-3Galbeta1-3[NeuAcalpha2-6]GalNAc-R), followed by 3-sialyl T antigen (NeuAcalpha2-3Galbeta1-3GalNAc-R), structures expressed on O-linked glycoproteins as well as on gangliosides.[PMID: 15701648] bGSL:d2f8c5be-c064-469b-8919-2a0cf3486ee9 disialyl-Lewis a disialyl Lea disialylated fucosylated glycan; sialyl Lewis a 1A G93400AK GSD:00047 GSD_GLYGEN_V1; EOG_VARKI_4E; GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE Disialyl Lewis is a sialyl Lewis a with an additional sialic acid attached at the C-6 position of penultimate GlcNAc. [PMID:15231659] Biosynthesis of disialyl Lewis a (Lea) was analyzed using previously cloned ST6GalNAc V and ST6GalNAc VI, which were responsible for the synthesis of alpha-series gangliosides.[PMID:12668675] bGSL:8891c884-7118-4fd3-ad60-62f9ad27647d disialyl-Lewis c sialyl Lewis c 1A G14000ZZ GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:23a17612-d020-416b-9015-b97a5e1375ca extended core-1 O-glycan O-glycan core 1 1A EOG_VARKI_4E An extended core-1 O-glycan is a core-1 O-glycan (Galβ1-3GalNAcα1-Ser/Thr) that is further elongated by the addition of extra monosaccharides, such as in the biosynthesis of sulfated selectin ligands. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch34/#:~:text=However%2C%20these%20transitions%20occur,of%20lymphocytes%20to%20lymph%20nodes'] bGSL:c1e09082-7a14-4eb1-8657-866a62c29a4b Extended GM1 1A G03506YN SUGARBIND bGSL:b3260457-54de-45fc-9e8d-3e13d948b471 Extended tetrafucosyl-Leb 1A CUMMINGS TRUE bGSL:6dc0b72a-5b4d-448c-9f4e-316e8c27a2cd Extended trifucosyl-Leb trifucosyl Lewis b 1A CUMMINGS TRUE bGSL:f9760e8d-3985-4cb2-ac07-5a1e43a67eef F1 alpha antigen F1 alpha 1A G21312EA; G61730RY GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:0be4d4b7-e083-4ce6-aaf7-b53eae57055d Forssman antigen Forssman glycolipid; Globopentosylceramide Cytolipin R; Gb5 1A G80062GG; G72565QB; G00064MO GSD:00050 GlycoMotif:GGM.000084; GlycoMotif:CCRC.000084; GlycoMotif:GDV.000061 GSD_GLYGEN_V1; CUMMINGS; GLYCOEPITOPE; SUGARBIND; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; PUBDICT_MOTIF_GTC A linear amino pentasaccharide comprising N-acetyl-α-D-galactosamine, N-acetyl-β-D-galactosamine, α-D-galactose, β-D-galactose and β-D-glucose residues linked sequentially (1→3), (1→3), (1→4) and (1→4).[CHEBI:85789] Analysis of metabolically labeled glycolipids released into the apical and basal culture medium, either as shed membrane vesicles or in budding viruses, also demonstrated the presence of the Forssman glycolipid on both apical and basolateral membranes of polarized cells.[PMID:3040119] bGSL:6423e054-e5e0-434d-ba27-206a3f058b43 Fuc-gangliotetraosylceramide H-5-ganglio Fuc-GgO4 Gg4 1A G57920AK SUGARBIND; PUBDICT_GLYCAN_MOTIF bGSL:cfff2d4a-1189-44e6-9853-fc7bd20b35dc Fucosyl Asialo-GM1 1A G57920AK GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:a4d581fd-a355-411d-b17a-b4af21aca340 Fucosyl GM1 2-fucosyl GM1 1A G91532KA GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV; BIOOLIGO bGSL:e3461cd4-411d-4673-aa6a-18c7fb7f77d7 Fucosylated B antigen type 5 1A BIOOLIGO bGSL:164c2029-560c-4f60-a18f-4d77955512cf GAG Core 1a 1A G24334HE GlycoMotif:GGM.001201 GLYCOMOTIF_GGM TRUE bGSL:aaa0f2ce-db6f-4c0d-8406-73c0ff6a8da9 GAG Core 1b 1A G68167JE GlycoMotif:GGM.001202 GLYCOMOTIF_GGM TRUE bGSL:0d00dcc0-fb8a-40e9-a5cf-d21291bc9a54 GAG Core 2a 1A G47726BP GlycoMotif:GGM.001203 GLYCOMOTIF_GGM TRUE bGSL:91064188-0226-4b6f-b2ea-9d555443e43f GAG Core 2b 1A G99404VQ GlycoMotif:GGM.001204 GLYCOMOTIF_GGM TRUE bGSL:eeb1c0e7-6923-4717-8b8b-583774330b3e GAG Core 3a 1A G71799OV GlycoMotif:GGM.001205 GLYCOMOTIF_GGM TRUE bGSL:215732a2-736a-4915-b74c-7670674c81d5 GAG Core 3b 1A G17755DI GlycoMotif:GGM.001206 GLYCOMOTIF_GGM TRUE bGSL:6f83a854-b24c-42ff-ab24-cbfe12771323 GAG Core 4a 1A G20313XP GlycoMotif:GGM.001207 GLYCOMOTIF_GGM TRUE bGSL:382b9bd6-0760-43e7-affc-4a543b2ff070 GAG Core 4b 1A G35577IC GlycoMotif:GGM.001208 GLYCOMOTIF_GGM TRUE bGSL:a6ede961-672a-4e0b-88d3-533749c189af GAG Core 5a 1A G83003HU GlycoMotif:GGM.001209 GLYCOMOTIF_GGM TRUE bGSL:aa498dff-84c9-46b7-a043-02d5001517c9 GAG Core 5b 1A G09365IF GlycoMotif:GGM.001210 GLYCOMOTIF_GGM TRUE bGSL:df3dd2cb-8b81-4910-9c2d-09ffcf34a00f GAG Core 6a 1A G40737XM GlycoMotif:GGM.001211 GLYCOMOTIF_GGM TRUE bGSL:605c506e-12a0-45ce-bb96-a586a46f1af0 GAG Core 6b 1A G01966AZ GlycoMotif:GGM.001212 GLYCOMOTIF_GGM TRUE bGSL:149edc05-9e99-44d2-aa65-e1163a91089a GAG Core 7a 1A G81019IW GlycoMotif:GGM.001213 GLYCOMOTIF_GGM TRUE bGSL:27d8e0e3-2d19-4142-ba1a-9aced993f85c GAG Core 7b 1A G58965WY GlycoMotif:GGM.001214 GLYCOMOTIF_GGM TRUE bGSL:005f31eb-c98d-495f-ab1b-ee6c925edb27 Gal-CTH 1A G91649BT GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:d7017257-a9f7-4624-b883-bc144a74e3b1 galabiosylceramide Digalactosylceramide glycosylceramide 1A G67988RO GSD:00058 GSD_GLYGEN_V1; GLYCOEPITOPE; SUGARBIND; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE A disaccharide consisting of β-D-galactopyranose having a D-galactopyranosyl residue attached at the 4-position via an α-linkage.[CHEBI:59314] LacCer and its structural isomer, galabiosylceramide (Gb2, Galβ(1,4)Galβ-ceramide), are classified as ceramide dihexosides (CDH).[PMID:33360824] bGSL:b838f4d7-0797-4802-acfb-153335f51f2f Galactocerebroside (2-hydoxy fatty acid) galactosylceramide 1A PUBDICT_GLYCONAVI_NAME TRUE bGSL:007eaf93-b6fc-4d23-a731-af8e3716eca0 Galactocerebroside (non-hydroxy fatty acid) galactosylceramide 1A PUBDICT_GLYCONAVI_NAME TRUE bGSL:68eb40eb-f4a1-4a35-a054-374badfc39a0 galactosylceramide Galactocerebroside; galactoceramide; LC GalCer; Gal-Cer; LC glycosylceramide; Galactocerebroside (non-hydroxy fatty acid) Galactocerebroside (2-hydoxy fatty acid) 1A G65889KE GSD:00059 GlycoMotif:GGM.000061; GlycoMotif:GDV.000053 GSD_GLYGEN_V1; EOG_VARKI_4E; CUMMINGS; GLYCOEPITOPE; SUGARBIND; GLYCOMOTIF_GGM; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE Galactosylceramide is a glycosphingolipid composed of a ceramide backbone with a single galactose residue β-linked to it. It is predominantly found in the nervous system, especially in brain and myelin lipids of deuterostome animals. Galactosylceramide improved behavioral, neuropathological, and biochemical parameters in Cln3 Cln3 Δex7/8 mice, paving the way for effective therapy for CLN3 disease and use of serum ceramide as a potential biomarker to track impact of therapies.[PMID:31393621] bGSL:318a5c9e-d07c-4111-acea-074a7a41ef13 Galactosylgloboside Gb5 1A G99053DY GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE A linear amino pentasaccharide comprising D-glucose at the reducing end with a β-D-galactosyl-(1→3)-N-acetyl-β-D-glucosaminyl-(1→3)-α-D-galactosyl-(1→4)-β-D-galactosyl moiety at the 4-position.[CHEBI:141842] bGSL:0f1bc566-aa3e-4418-9de1-ffe7b008a50c Galili antigen Galili-tri alpha-gal antigen 1A PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV; BIOOLIGO bGSL:988e192b-2add-441f-80df-39aefcda2754 Galili antigen pentaose 1A BIOOLIGO TRUE bGSL:9b251aa4-1b1b-4e83-a9c5-89ce715e98a4 GalNAc disialyl Lc4 hexasaccharide 1A G33532XU GSD:00163 GSD_GLYGEN_V1; GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE (2R,4S,5R,6R)-5-Acetamido-2-[[(2R,3S,4R,5R,6S)-5-acetamido-4-[(2R,3R,4R,5S,6R)-4-[(2S,4S,5R,6R)-5-acetamido-2-carboxy-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxan-2-yl]oxy-5-[(2S,3R,4R,5R,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-hydroxy-6-[(3R,4S,5S,6R)-2,3,5-trihydroxy-6-(hydroxymethyl)oxan-4-yl]oxyoxan-2-yl]methoxy]-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid is a member of neuraminic acids.[CID:91857945] Therefore, a new marker for prostate cancer is urgently required. We examined expression of a novel carbohydrate antigen, beta1,4-GalNAc-disialyl-Lc(4), defined by the monoclonal antibody RM2, in prostate cancer using 75 cases of radical prostatectomy specimens.[PMID: 12084983] bGSL:4dcd7634-d55e-4502-b42a-481bc97dac63 GalNAc-GD1a N-acetylgalactosaminyl-GD1a 1A G92175CL GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:27ccc0f6-ef26-4a03-838d-36f6cd42a69f Galα1-3-Lewis x alpha-galactosyl-Lewis x Gala3Lex 1A PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV bGSL:89f756f9-bab4-40b2-839b-f359ec86e26a Gb3 globotriaosylceramide; Globotriose GL3; Gb(3) CD77; Pk antigen; ceramide trihexoside 1A G00059MO GSD:00072 GlycoMotif:GGM.000068 EOG_VARKI_4E; GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; GSD_GLYGEN_V1; SUGARBIND; PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV Gb3, also known as the Pk antigen, is a type of glycosphingolipid containing a trisaccharide core structure with the sequence Galα1-4Galβ1-4Glc. It acts as a receptor for Shiga toxins. bGSL:822d8466-4137-40ed-9e95-7f2785c63d13 Gb4 globoside-4; globotetraosylceramide; Globotetraosylceramide; Globotetraose; GalNAcβ1-3Galα1-4Galβ1-4Glc Gb4Cer Tetraosylceramide Blood group H tetraose type 4; P antigen; cytolipin K; globoside; globoside I 1A G00061MO GSD:00067 GlycoMotif:GGM.000070 EOG_VARKI_4E; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV; GSD_GLYGEN_V1; SUGARBIND Gb4, also known as globoside, is a type of glycosphingolipid containing a tetrasaccharide core structure with the sequence GalNAcβ1-3Galα1-4Galβ1-4Glc, found in the P antigen (Gb4) glycosphingolipid. bGSL:c49f645c-0c03-4fc7-ab52-5ffe069bf714 Gb5 Globopentaosylceramide; globopentaosylceramide glycosylceramide disialosyl globopentaosylceramide; monosulfated globopentaosylceramide; monosialyl Gb5 Forssman antigen; SSEA-3; Galactosylgloboside 1A G99053DY; G88796WA; G19298OA GSD:00060 GlycoMotif:GGM.000076; GlycoMotif:CCRC.000076; GlycoMotif:GDV.000029 GSD_GLYGEN_V1; CUMMINGS; SUGARBIND; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE A linear amino pentasaccharide comprising D-glucose at the reducing end with a β-D-galactosyl-(1→3)-N-acetyl-β-D-glucosaminyl-(1→3)-α-D-galactosyl-(1→4)-β-D-galactosyl moiety at the 4-position.[CHEBI:141842] bGSL:faee5f8f-038c-47f6-b3c7-ebb0332f3129 GD1 1A G81983KG GlycoMotif:GDV.000126 CUMMINGS; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF bGSL:4e761137-67d4-4655-9b81-036eedacbbf3 GD1a-alpha GD1alpha; ganglioside GD1a Disialogangliotetraosylceramide 1A G46677TE; G45714BQ; G13258LA; G69277LC; G07394RV GSD:00062 GlycoMotif:GGM.000106; GlycoMotif:GGM.000107; GlycoMotif:CCRC.000106; GlycoMotif:CCRC.000107; GlycoMotif:GDV.000096; GlycoMotif:GDV.000099 GSD_GLYGEN_V1; EOG_VARKI_4E; CUMMINGS; GLYCOEPITOPE; SUGARBIND; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV A branched amino hexasaccharide consisting of the linear sequence α-Neu5Ac-(2→3)-β-D-Gal-(1→3)-β-D-GalNAc-(1→4)-β-D-Gal-(1→4)-β-D-Glc having a Neu5Ac residue attached to a galactose via an α-(2→3) linkage. The oligosaccharide of ganglioside GD1a.[CHEBI:59209] Exclusive exposure of rat oligodendrocytes to GD1a, but not other gangliosides, overcomes aggregated fibronectin-induced inhibition of myelin membrane formation, in vitro, and OPC differentiation in fibronectin aggregate containing cuprizone-induced demyelinated lesions in male mice. [PMID: 28899916] bGSL:9cfc2650-cfbe-48e9-a924-b4a674acfc3c GD1b ganglioside GD1b; Disialoganglioside; NeuAc-GD1b b-series gangliosides; Disialogangliotetraosylceramide 2-fucosyl GD1b; B-GD1b 1A G37184KW; G97612UN GSD:00063 GlycoMotif:GGM.000108; GlycoMotif:CCRC.000108; GlycoMotif:GDV.000031 GSD_GLYGEN_V1; EOG_VARKI_4E; CUMMINGS; GLYCOEPITOPE; SUGARBIND; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV; BIOOLIGO A branched amino hexasaccharide comprising a β-D-galactosyl-(1→4)-β-D-glucose disaccharide, the galactosyl residue of which carries β-D-galactosyl-(1→3)-N-acetyl-β-D-galactosaminyl and N-acetyl-α-neuraminyl-(2→8)-N-acetyl-α-neuraminyl disaccharide units through (2→4) and (2→3) linkages respectively. It is the carbohydrate portion of ganglioside GD1b.[CHEBI:59222] Gangliosides have been known to play a role in the regulation of apoptosis in cancer cells. This study has employed disialyl-ganglioside GD1b to apoptosis in human breast cancer MCF-7 cells using exogenous treatment of the cells with GD1b and endogenous expression of GD1b in MCF-7 cells.[PMID: 27144558] bGSL:bbe481d9-8fea-4f8d-a244-c730590c7929 GD1c ganglioside GD1 1A G81983KG; G24638PB GSD:00061 GlycoMotif:GGM.000105; GlycoMotif:CCRC.000105 GSD_GLYGEN_V1; EOG_VARKI_4E; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; PUBDICT_GLYCAN_MOTIF GD1 refers to a class of acidic glycosphingolipids known as gangliosides that contain two sialic acid residues. These molecules are commonly found in neural tissues, and the GD1 group includes specific members such as GD1a and GD1b. Hormonal and metabolic disturbances observed in both adult and paediatric patients with Gaucher disease type 1 (GD1) are discussed in this review. The PubMed database was used to identify articles on endocrine and metabolic disorders in GD1.[PMID:31791361] bGSL:c37f7e51-d0ed-478b-9e67-f53aa08cb407 GD2 NeuAc-GD2 1A G02657AK; G41759HA GSD:00064 GlycoMotif:GGM.000094; GlycoMotif:CCRC.000094; GlycoMotif:GDV.000071 GSD_GLYGEN_V1; CUMMINGS; GLYCOEPITOPE; SUGARBIND; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV; BIOOLIGO A branched amino pentasaccharide consisting of a linear sequence of two α-sialyl residues, a β-D-galactosyl residue and an N-acetyl-β-D-glucosamine residue linked respectively (2→8), (2→8) and (1→4), to the galactosyl residue of which is also linked (1→4) an N-acetyl-β-D-glucosaminyl residue. It is the carbohydrate portion of ganglioside GD2.[CHEBI:59218] Ganglioside GD2 is a tumor-associated surface antigen found in a broad spectrum of human cancers and stem cells. [PMID: 25440605] bGSL:b3e8524f-c1ae-435d-897f-6dbd70f2e851 GD3 9-O-acetyl GD3 1A G98544DH; G81928IQ GSD:00065 GlycoMotif:GGM.000091; GlycoMotif:CCRC.000091; GlycoMotif:GDV.000127; GlycoMotif:GDV.000129 GSD_GLYGEN_V1; CUMMINGS; GLYCOEPITOPE; SUGARBIND; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV; BIOOLIGO A linear amino tetrasaccharide consisting of two sialyl, one galactose and one glucose residue (at the reducing end) connected by sequential α-(2→8)-, α-(2→3)- and β-(1→4)-linkages. The oligosaccharide of ganglioside GD3.[CHEBI:59210] In mammalian cells, the intracellular accumulation of ganglioside GD3, an acidic glycosphingolipid, contributes to mitochondrial damage, a crucial event during the apoptopic program. [PMID: 12531552] bGSL:dee076ed-be4d-4ce9-8170-1099624bf90c Gg3 Asialo-GM2; Asialo-GM2a; GA2; Gangliotriaosylceramide; Gangliotriose GA2 1A G90562PB SUGARBIND; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV; BIOOLIGO bGSL:199f12a4-f960-48c9-9a3e-588a3863a852 Gg4 ganglioside Gg4; Gangliotetraosylceramide; GA1; GgO4; Gangliotetraose; ganglioside GA1; ganglio-N-tetraosylceramide GgO4; GA1; as-GM1 Monosulfated gangliotetraosylceramide Fuc-gangliotetraosylceramide; Monosulfated gangliotetraosylceramide asialo-GM1 1A G21856LC; G05357CB; G00407UJ EOG_VARKI_4E; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; SUGARBIND; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV Gg4 (gangliotetraosylceramide) is a glycosphingolipid, specifically a ganglioside, consisting of a ceramide backbone attached to a tetrasaccharide chain. It belongs to the globo-series of glycolipids. bGSL:93fc120b-d2fd-4a8b-b137-f80a6ca530b8 Gg4Cer II3-sulfate SM1a 1A G59508TM SUGARBIND; PUBDICT_GLYCAN_MOTIF bGSL:7437d5bc-5e41-4de3-ace6-132af6c10e9d Gg5 gangliopentaosylceramide 1A G96834JC PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:98dff1be-0bac-4a70-9e8b-f15565829ad6 GH1c alpha GH1calpha; GH1cα 1A G14091MR; G86139YL GlycoMotif:GGM.000120; GlycoMotif:CCRC.000120; GlycoMotif:GDV.000122 CUMMINGS; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF bGSL:e064e2cd-c74a-4a4a-af5b-58fa4ddd2d5e GlcNAc b(1-2') TF 1A BIOOLIGO bGSL:dfc160a6-59f5-4853-945a-98acceafee6f Globo-A blood group A heptaose type 4 [sb] blood group A type 4 1A G37830TX SUGARBIND bGSL:2b1e2dd8-833e-5309-9bcd-d7896a08ed5a Globo-H GL-6 fucosylated (globoH); globoH blood group H type 4 1A G98465JN; G83120FP GlycoMotif:GGM.000078; GlycoMotif:CCRC.000078; GlycoMotif:GDV.000008 SUGARBIND; PUBDICT_GLYCAN_MOTIF; CUMMINGS; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV bGSL:00d4afcc-73bb-42dd-9a1b-68977bbe136c globoside Gb4 1A G00061MO GSD:00068 GlycoMotif:GGM.000070; GlycoMotif:GDV.000065 GSD_GLYGEN_V1; CUMMINGS; GLYCOEPITOPE; GLYCOMOTIF_GGM; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE Gb4, also known as globoside, is a type of glycosphingolipid containing a tetrasaccharide core structure with the sequence GalNAcβ1-3Galα1-4Galβ1-4Glc, found in the P antigen (Gb4) glycosphingolipid. bGSL:c7bdd8f1-eb83-431f-a6ed-38af3e72f24d globoside I Gb4 1A G00061MO GSD:00069 GlycoMotif:GGM.000070 GSD_GLYGEN_V1 Gb4, also known as globoside, is a type of glycosphingolipid containing a tetrasaccharide core structure with the sequence GalNAcβ1-3Galα1-4Galβ1-4Glc, found in the P antigen (Gb4) glycosphingolipid. bGSL:f01b2d5f-f962-4505-b4a3-7f05d971d8fd Glucopsychosine 1A PUBDICT_GLYCONAVI_NAME bGSL:c3d0b1db-a38c-4e77-b591-2979ce594455 Glucosylceramide CMH; Ceramide monohexoside GlcCer glycosylceramide Lc3 1A G71142DF SUGARBIND; PUBDICT_GLYCONAVI_NAME bGSL:dda7b7e5-a602-46e8-b407-d6b6a3373a49 glycoinositolphospholipids GIPLs glycolipids 1A EOG_VARKI_4E Glycoinositolphospholipids (GIPLs) are a class of glycolipids structurally related to glycosylphosphatidylinositol (GPI) anchors, but are distinguished by extensive substitution with galactose, N-acetylglucosamine, and sialic acid residues. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch43/#:~:text=brucei%20and%20Trypanosoma%20cruzi.,in%20the%20mammalian%20bloodstream'] bGSL:17a8e2b6-e094-4aee-ad97-2bdaf965c661 glycosylceramide GlcNAcβ1-4Glc-Cer; galactosylceramide; galabiosylceramide; sialopentaosylceramide; ceramide dihexosyl sulfate; Glucosylceramide; ganglio-series glycosphingolipid; Gb5 1A EOG_VARKI_4E Glycosylceramides are glycolipids consisting of a ceramide backbone linked to a short glycan chain, such as glucosylceramide (Glc-Cer) and galactosylceramide (Gal-Cer). These molecules are commonly found in fungi and play important roles in membrane structure and function. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch23/#:~:text=fumigatus%29%20or%20additional%20mannose,biosynthesis%20%28Chapter%2012%29'] bGSL:fb6c2664-1ae2-4e3c-9230-4a704c84f3db glycosylinositolphosphorylceramide glycosylinositolphosphorylceramides GIPCs 1A EOG_VARKI_4E Glycosylinositolphosphorylceramides (GIPCs) are plant- and fungi-specific glycolipids composed of a ceramide backbone linked to a glycosylated inositol phosphate headgroup. They are major components of the plant plasma membrane and are absent in animals. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch24/#:~:text=The%20presence%20and%20abundance%20of%20MGDG,more%20than%20200%20species%20described', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch24/#:~:text=GIPCs%20are%20estimated%20to%20comprise%20up,membranes%20remain%20to%20be%20confirmed'] ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch24/#:~:text=The%20presence%20and%20abundance%20of%20MGDG,more%20than%20200%20species%20described'] bGSL:7c8ec55b-1f49-42c3-98dc-c22243434067 GM1 GM1 ganglioside; ganglioside GM1; NeuAc-GM1; Monosialoganglioside GM1a; GM1b Monosialogangliotetraosylceramide 1A G48558GR; G46613JI; G03277YI GSD:00074 GlycoMotif:GGM.000098; GlycoMotif:CCRC.000098; GlycoMotif:GDV.000030 GSD_GLYGEN_V1; EOG_VARKI_4E; CUMMINGS; GLYCOEPITOPE; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV A branched amino pentasaccharide consisting of the linear sequence β-D-Gal-(1→3)-β-D-GalNAc-(1→4)-β-D-Gal-(1→4)-β-D-Glc having a Neu5Ac residue attached to the inner galactose via an α-(2→3) linkage. The oligosaccharide of ganglioside GM1a.[CHEBI:59208] bGSL:532d80fe-4ee6-4dde-8608-8350a4fff7ab GM1a GM1 1A G48558GR GSD:00182 GSD_GLYGEN_V1; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE Related synonym extracted from gsdv1 edge. See edges.jsonl for the linked subject term. bGSL:425941b1-430f-4868-a3d8-c0abb9cc862c GM1b ganglioside GM1b GM1 B-GM1 1A G03277YI EOG_VARKI_4E; GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE GM1b is a ganglioside with the structure Neu5Acα2-3Galβ1-3GalNAcβ1-4Galβ1-4Glcβ1-1Cer. It is biosynthesized by the α2-3 sialylation of GA1. It participates in membrane organization and cell–cell recognition. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch31/#:~:text=In%20each%20subunit%2C%20the%20%CE%B1-%20and,of%20the%20ganglioside%20%28Chapter%2020%29'] bGSL:9bfcdda2-bc45-4723-92dc-5fda366d9c59 GM2 ganglioside GM2; NeuAc-GM2 1A G79389NT; G61168WC GSD:00075; GSD:00109 GlycoMotif:GGM.000095; GlycoMotif:CCRC.000095; GlycoMotif:GDV.000069 GSD_GLYGEN_V1; EOG_VARKI_4E; CUMMINGS; GLYCOEPITOPE; SUGARBIND; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV A branched amino tetrasaccharide consisting of the linear sequence β-D-GalNAc-(1→4)-β-D-Gal-(1→4)-β-D-Glc having a Neu5Ac residue attached to the galactose via an α-(2→3) linkage. Corresponds to the carbohydrate portion of ganglioside GM2.[CHEBI:59220] GM1 gangliosidosis has both central nervous system and systemic findings; while, GM2 gangliosidosis is restricted primarily to the central nervous system.[PMID: 27491214] bGSL:f7a8d6f9-44d5-42a1-b56e-2e28650d0e4c GM3 ganglioside GM3; Hematoside; II3NeuAc LacCer GM3; II3NeuAc LacCer N-Acetyl GM3; N-Glycolyl GM3 1A G91237TK; G56516VH GSD:00076 GlycoMotif:GGM.000090; GlycoMotif:CCRC.000090; GlycoMotif:GDV.000108 GSD_GLYGEN_V1; EOG_VARKI_4E; CUMMINGS; SUGARBIND; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV Ganglioside GM3 (d18:1/16:0) is a glycosphingolipid (ceramide and oligosaccharide)or oligoglycosylceramide with one or more sialic acids (i.e. n-acetylneuraminic acid) linked on the sugar chain. It is a component the cell plasma membrane which modulates cell signal transduction events. Gangliosides have been found to be highly important in immunology. Ganglioside GM3 carries a net-negative charge at pH 7.0 and is acidic. Gangliosides can amount to 6% of the weight of lipids from brain, but they are found at low levels in all animal tissuesGangliosides are glycosphingolipids. There are four types of glycosphingolipids, the cerebrosides, sulfatides, globosides and gangliosides. Gangliosides are very similar to globosides except that they also contain N-acetyl neuraminic acid (NANA) in varying amounts. The specific names for the gangliosides provide information about their structure. The letter G refers to ganglioside, and the subscripts M, D, T and Q indicate that the molecule contains mono-, di-, tri and quatra-sialic acid. The numbered subscripts 1, 2 and 3 refer to the carbohydrate sequence that is attached to the ceramide. In particular, 1 stands for GalGalNAcGalGlc-ceramide, 2 stands for GalNAcGalGlc-ceramide and 3 stands for GalGlc-ceramide. Deficiencies in lysosomal enzymes that degrade the carbohydrate portions of various gangliosides are responsible for a number of lysosomal storage diseases such as Tay-Sachs disease, Sandhoff disease, and GM1 gangliosidosis. The carbohydrate portion of the ganglioside GM1 is the site of attachment of cholera toxin, the protein secreted by Vibrio cholerae.[HMDB0004844] We also demonstrated an essential role of GM3 in murine and human auditory systems; a common pathological feature of GM3S deficiency is deafness. [PMID: 29747813] bGSL:2eae0ebe-4d6e-453f-a074-4029065d9d6f GM4 1A G30207PZ; G77824XV GSD:00077 GlycoMotif:GGM.000089; GlycoMotif:CCRC.000089; GlycoMotif:GDV.000113 GSD_GLYGEN_V1; CUMMINGS; GLYCOEPITOPE; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE An amino disaccharide consisting of β-D-galactose having an α-N-acetylneuraminyl residue attached at the 3-position [CHEBI:63155] GM4 is synthesized by the sialylation of galactosylceramide (GalCer), while the ganglioside GM3 is synthesized by the sialylation of lactosylceramide (LacCer).[PMID:23999868] bGSL:f62ea337-d62f-41a7-9814-c768662e4143 GP1c GP1calpha 1A G93805MV; G04433GV; G77608BK; G16999RL; G26203DP; G00552RX GSD:00078 GlycoMotif:GGM.000118; GlycoMotif:GGM.000119; GlycoMotif:CCRC.000118; GlycoMotif:CCRC.000119; GlycoMotif:GDV.000095; GlycoMotif:GDV.000125 GSD_GLYGEN_V1; CUMMINGS; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE n this report, we describe an efficient convergent synthesis of the GP1c glycolipid epitope, which is one of the most complex c-series gangliosides. [PMID:19053458] bGSL:45cf6056-725f-4fb7-9d95-f1683f991db6 GPI anchor core GPI glycan 1A G00045MO PUBDICT_GLYCAN_MOTIF; EOG_VARKI_4E GPI glycans are the glycan (oligosaccharide) portion of glycosylphosphatidylinositol (GPI) anchors, which are glycolipid structures that tether proteins to the outer leaflet of the plasma membrane. The core GPI glycan consists of a conserved sequence, typically including mannose and glucosamine residues linked to myo-inositol phospholipid, and serves as a scaffold for further modifications and protein attachment. GPI glycans can vary between species and tissues, contributing to the diversity of GPI-anchored proteins, and may include additional side chains. In some organisms, the lipid component is inositolphosphoceramide. The GPI glycan is preassembled before protein attachment and is essential for the function of GPI anchors. bGSL:1fae7ee0-c40d-43c2-9ccb-8d15287d5de7 GQ1a alpha GQ1aalpha; GQ1aα 1A G90598GO; G26199BG GlycoMotif:GGM.000114; GlycoMotif:CCRC.000114; GlycoMotif:GDV.000121 CUMMINGS; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF bGSL:f9b92d46-4b8e-4ce2-8efa-d84c35599a6b GQ1b ganglioside GQ1b; NeuAc-GQ1b GQ1b alpha 1A G18625KA; G17077FL GSD:00079 GlycoMotif:GGM.000115; GlycoMotif:CCRC.000115; GlycoMotif:GDV.000124 GSD_GLYGEN_V1; EOG_VARKI_4E; CUMMINGS; GLYCOEPITOPE; SUGARBIND; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV An amino oligosaccharide that is a branched octasaccharide derivative consisting of four sialyl residues, two galactose residues, one N-acetylglucosamine and a glucose residue at the reducing end.[CHEBI:59212] Bilateral infusion of GQ1b into the hippocampus ameliorates cognitive deficits in the triple-transgenic AD mouse model (3xTg-AD).[PMID:31186474] bGSL:e0f1b943-4db3-40a1-a2ab-362d11a14bae GQ1b alpha GQ1ba; GQ1balpha GQ1b 1A G54733XO; G49791FJ GSD:00165 GlycoMotif:GGM.000116; GlycoMotif:CCRC.000116; GlycoMotif:GDV.000091 GSD_GLYGEN_V1; CUMMINGS; GLYCOEPITOPE; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE A few studies have reported the association of autoantibodies to GM1 or GQ1bα with Alzheimer's disease (AD) or vascular dementia.[PMID:25024341] bGSL:3fe88f61-80b9-4961-9325-808a97b806d9 GQ1c 1A G99524KA; G54442GQ GSD:00080 GlycoMotif:GGM.000117; GlycoMotif:CCRC.000117; GlycoMotif:GDV.000101 GSD_GLYGEN_V1; CUMMINGS; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE Alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)-[alpha-Neu5Ac-(2->3)-beta-D-Galp-(1->3)-beta-D-GalpNAc-(1->4)]-beta-D-Galp-(1->4)-beta-D-Glcp is a member of neuraminic acids and an amino octasaccharide.[CID:91860352] The neural specific monoclonal antibody A2B5 was found to interact with GQ1c but not with Gq1b, nor did it interact with other glycolipids such as GM1, GD1a, GD1b, GT1a, GT1b and GA1.[PMID: 6640289] bGSL:e928e3a3-7521-4db4-ac0a-22b9ca329c38 GQ2 1A PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV bGSL:48415eae-c422-4cff-a82b-d0d4131fde28 GT1a GT1aa; GT1a alpha; GT1aalpha 1A G68110IF; G02149VR; G93468NI; G17486WU GSD:00081; GSD:00166 GlycoMotif:GGM.000110; GlycoMotif:GGM.000111; GlycoMotif:CCRC.000110; GlycoMotif:CCRC.000111; GlycoMotif:GDV.000094; GlycoMotif:GDV.000123 GSD_GLYGEN_V1; CUMMINGS; GLYCOEPITOPE; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; BIOOLIGO A branched heptasaccharide derivative consisting of three sialyl residues, two galactose residues, one N-acetylglucosamine and a glucose residue at the reducing end.[CHEBI:59215] GT1a mimicry was found in the lipo-oligosaccharides of strain ICDCCJ07002 and ICDCCJ07004; but a combination of GM3/GD3 mimics was observed in ICDCCJ07001, although this patient had anti-GT1a IgG antibodies.[PMID:26197476] bGSL:e969dbb4-1662-4f69-85bf-c01b4deecee9 GT1c ganglioside GT1c 1A G78818SP; G50762GU GSD:00083 GlycoMotif:GGM.000113; GlycoMotif:CCRC.000113; GlycoMotif:GDV.000032 GSD_GLYGEN_V1; EOG_VARKI_4E; CUMMINGS; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; BIOOLIGO A branched amino heptasaccharide consisting of a linear tetrasaccharide of β-D-galactose, N-acetyl-β-D-galactosamine, β-D-galactose and β-D-glucose residues linked sequentially (1→3), (1→4) and (1→4), to the galactose residue proximal to the reducing end is also linked (2→3) an N-acetyl-α-neuraminyl-(2→8)-N-acetyl-α-neuraminyl-(2→8)-N-acetyl-α-neuraminyl trisaccharide side-chain. The carbohydrate moiety of ganglioside GT1c.[CHEBI:90509] We show here that VVH associates with ganglioside GM1a, Fucosyl-GM1, GD1a, GT1c, and GD1b by glycan array.[PMID: 32228455] bGSL:1adbf32d-389e-4df4-b4ee-b3566262a7aa GT2 1A G36476BA; G35228ZS GSD:00084 GlycoMotif:GGM.000109; GlycoMotif:CCRC.000109; GlycoMotif:GDV.000072 GSD_GLYGEN_V1; CUMMINGS; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV; BIOOLIGO A branched amino hexasaccharide consisting of a chain of three α-sialyl residues, a β-D-galactosyl residue and a β-D-glucose residue linked sequentially (2→8), (2→8), (2→3) and (1→4), to the galactosyl residue of which is also linked (1→4) an N-acetyl-β-D-galactosaminyl residue. The carbohydrate moiety of ganglioside GT2.[CHEBI:72446] Biosynthesis of the c-series gangliosides GT3, GT2 and GP1c was studied in Golgi derived from rat liver.[PMID:1606358] bGSL:7bf449b5-9963-429e-9223-0721c3a0b3f3 GT3 1A G93899SO; G33570YF GSD:00085 GlycoMotif:GGM.000092; GlycoMotif:CCRC.000092; GlycoMotif:GDV.000128 GSD_GLYGEN_V1; CUMMINGS; GLYCOEPITOPE; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV; BIOOLIGO A linear amino pentasaccharide consisting of a chain of three α-sialyl residues, a β-D-galactosyl residue and a β-D-glucose residue linked sequentially (2→8), (2→8), (2→3) and (1→4).[CHEBI:72444] The purpose of this study was two-fold: (1) to formulate γ-tocotrienol (GT3) in a nanoemulsion formulation as a prophylactic orally administered radioprotective agent; and (2) to optimize the storage conditions to preserve the structural integrity of both the formulation and the compound.[PMID: 28029115] bGSL:16841e45-37fd-428d-acee-244ea2469bfc heparan sulfate heparan sulphate; heparan sulfate backbone HS 1A GSD:00086 GSD_GLYGEN_V1; EOG_VARKI_4E; GLYCOEPITOPE; PUBDICT_GLYCAN_IMAGE A linear polysaccharide in which the backbone consists of a variably sulfated repeating disaccharide unit.[CHEBI:28815] In Niemann-Pick C-1 fibroblasts, where deaminative degradation of heparan sulfate is defective, carbonylated proteins were abundant.[PMID: 17540770] bGSL:a5f05e19-948a-449e-8d67-c17dcf06db93 heparin 1A G00021MO; G54161DR GSD:00087 GSD_GLYGEN_V1; EOG_VARKI_4E; PUBDICT_GLYCAN_MOTIF; PUBDICT_MOTIF_GTC A highly sulfated linear glycosaminoglycan comprising complex patterns of uronic acid-(1→4)-D-glucosamine repeating subunits. Used as an injectable anticoagulant, it has the highest negative charge density of any known biological molecule.[CHEBI:28304] Two cellulose-based membranes, containing 5 and 20% N, N-diethyl-aminoethyl cellulose (DEAE) respectively, were investigated for ionic attachment of heparin and heparin release.[PMID:6416324] bGSL:9fecaa24-6510-4b47-b002-a561726a2062 Hexaosylceramide 1A G83212YI SUGARBIND bGSL:7653bdd7-2494-4ac5-a01a-01e3ad9941c5 HNK-1 HNK-1 epitope; HNK-1 antigen; Human Natural Killer-1 carbohydrate; Human Natural Killer-1 HNK-1 on O-mannose 1A G54406UD; G53277CD; G89591DK GSD:00089 GlycoMotif:GGM.000058; GlycoMotif:CCRC.000058; GlycoMotif:GDV.000081 GSD_GLYGEN_V1; EOG_VARKI_4E; CUMMINGS; GLYCOEPITOPE; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE An amino trisaccharide consisting of a 3-O-sulfo-β-D-glucuronic acid residue, a D-galactosyl residue and an N-acetyl-D-glucosamine residue (at the reducing end) in a linear sequence.[CHEBI:60322] The human natural killer-1 (HNK-1) carbohydrate, a unique trisaccharide possessing sulfated glucuronic acid in a non-reducing terminus (HSO3-3GlcAß1-3Galß1-4GlcNAc-), is highly expressed in the nervous system and its spatiotemporal expression is strictly regulated.[PMID:28709864] bGSL:48198204-07a2-4f3a-8956-6387ffab5afd HNK-1 on O-mannose HNK-1 1A G06898ZN; G60606QD; G82061CN GlycoMotif:GGM.000059; GlycoMotif:CCRC.000059; GlycoMotif:GDV.000079 CUMMINGS; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF bGSL:8c7841f3-b492-4ba8-b482-d56660fefe72 hyaluronan HA Hyalonuric acid hexasaccharide 1A G29086KO; G00017MO GSD:00091 GSD_GLYGEN_V1; EOG_VARKI_4E; PUBDICT_GLYCAN_MOTIF; PUBDICT_MOTIF_GTC Hyaluronan is a high-molecular-weight, linear, nonsulfated glycosaminoglycan composed of repeating disaccharide units of glucuronic acid (GlcA) β1-3 linked to N-acetylglucosamine (GlcNAc) β1-4. These long, polyanionic chains occupy large hydrodynamic volumes and play important roles in cell adhesion, signaling, and tissue structure. Short hyaluronan chains or oligosaccharides, generated by enzymatic cleavage, can interact with membrane proteins such as CD44 and TLR2/4, modulating signaling pathways and inducing biological effects including apoptosis in cancer cells. Hyaluronan (HA) comprises a major component of the extracellular matrix (ECM) in vertebrate connective tissues and is abundant in the cartilage, skin, brain, vitreous body, umbilical cord, and synovial fluid. [PMID:33171800] bGSL:4ac5cae3-25cd-4daa-8044-b1b38a136a7b i antigen N-acetyllactosamine (type 2) Type 2 LN2; LN3 1A G00058MO; G46055MA GSD:00092 GlycoMotif:GGM.000004; GlycoMotif:GGM.000002 GSD_GLYGEN_V1; EOG_VARKI_4E; CUMMINGS; GLYCOEPITOPE; GLYCOMOTIF_GGM; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE The i antigen consists of repeating disaccharide units of N-acetyllactosamine (Galβ1-4GlcNAcβ1-3/6) arranged in a linear fashion. These linear poly-N-acetyllactosamine chains can act as precursors for further branching and are involved in the biosynthesis of antigens such as the I antigen. Inasmuch as the hybridoma was established by hybridization of lymphocytes derived from regional lymph nodes of lung cancer, and the antigen was found in the patient's lung cancer tissue, the i antigen in lung cancer is probably recognized as a tumor-associated antigen by the host's immune cell system.[PMID:2422274] bGSL:6c9d9542-d250-4e86-94ad-03739cbe4de3 I antigen disialyl I antigen 1A G56045WU GSD:00093 GlycoMotif:GGM.000003; GlycoMotif:CCRC.000004; GlycoMotif:GDV.000040; GlycoMotif:GDV.000044 GSD_GLYGEN_V1; EOG_VARKI_4E; CUMMINGS; GLYCOEPITOPE; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE N-[(2R,3R,4R,5S,6R)-5-[(2S,3R,4S,5S,6R)-4-[(2R,3R,4R,5S,6R)-3-Acetamido-4-hydroxy-6-(hydroxymethyl)-5-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-6-[[(2R,3R,4R,5S,6R)-3-acetamido-4-hydroxy-6-(hydroxymethyl)-5-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxymethyl]-3,5-dihydroxyoxan-2-yl]oxy-2,4-dihydroxy-6-(hydroxymethyl)oxan-3-yl]acetamide (CHEBI:151390) is a amino sugar.[CHEBI:151390] The I antigen is formed by the action of an enzyme (a glycosyltransferase), which adds branches onto the i antigen.[PMID:15679458] bGSL:ff846a03-9531-4fdb-b554-32ff4a31d3ea i-active ganglioside NeuAca3-nLc6; NeuAca2-3i; NeuAc-G-10; NeuAca2-3I 1A G03067VG; G28566CQ; G16194TN SUGARBIND; PUBDICT_GLYCAN_MOTIF bGSL:15bad56d-869e-473d-887d-d72feaca434d iGb3 Isoglobotri; Isoglobotriaosylceramide; Isoglobotriose IGb3; iGB3 1A G78074HX SUGARBIND; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV; BIOOLIGO bGSL:ae656af0-8c89-4a3d-9799-4e3ef0d3c106 iGb4 Isoglobotetraose; isoglobotetraosylceramide iGB4 Tetraosylceramide Cytolipin R 1A G57710SU; G19926LY; G32862WC GSD:00094 GlycoMotif:GGM.000071; GlycoMotif:CCRC.000071; GlycoMotif:GDV.000064 PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; BIOOLIGO; GSD_GLYGEN_V1; CUMMINGS; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF bGSL:66323db3-328b-484c-85b2-6ef77485d738 iGb5 Isoglobopentaose iGB5 1A BIOOLIGO bGSL:4e8c776f-6708-43c9-8561-8c26fc731ddb Internal Blood Group H blood group H 1A G82749ZI PUBDICT_GLYCAN_MOTIF bGSL:77554c0f-1a3a-4024-9105-845678bc1831 Internal Lewis x Lewis x 1A G64227KZ GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:324983e1-9aae-43e3-a0cc-c1c774cdc7d8 keratan sulfate kerato sulfate; keratan sulphate KS 1A G82109MW; G00020MO GSD:00095 GSD_GLYGEN_V1; EOG_VARKI_4E; GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; PUBDICT_MOTIF_GTC A sulfated glycosaminoglycan, a linear polymer that consists of the repeating disaccharide [3)-β-Gal-(1→4)-β-GlcNAc-(1→] and containing sulfo groups located at random positions.[CHEBI:60924] Compared to the other classes of glycosaminoglycans (GAGs), that is, chondroitin/dermatan sulfate, heparin/heparan sulfate and hyaluronan, keratan sulfate (KS), have the least known of its interactive properties.[PMID: 30578672] bGSL:7e280b3b-979f-4282-8b4f-f54265807bc6 keratan sulfate type I N-linked KS; corneal-type KS KS-I 1A EOG_VARKI_4E A type of N-glycan that carries corneal-type keratan sulfate (KS, type I) chains and is degraded by enzymes involved in N-glycan catabolism. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch44/#:~:text=Galactose-6-SO4%20sulfatase%20is%20the,sulfatase%20deficiency%20%28MSD%29'] bGSL:4055f7c9-98d4-4f75-90ac-521168c83b41 keratan sulfate type II O-linked KS; skeletal-type KS KS-II 1A EOG_VARKI_4E Keratan sulfate is a glycosaminoglycan that can be O-linked to proteins, especially in skeletal tissues (type II). ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch44/#:~:text=Galactose-6-SO4%20sulfatase%20is%20the,sulfatase%20deficiency%20%28MSD%29'] bGSL:254e5a33-c26a-4da2-895b-c393714d089f Lacto-N-fucopentaose I LNFP I Lacto-N-fucopentose 1A BIOOLIGO bGSL:11ba23bf-2e93-4688-b0df-1792e8599237 Lacto-N-fucopentose LNFP Lacto-N-fucopentaose I 1A G98173LG SUGARBIND bGSL:3f3cbc0e-120e-4478-836d-6e7a4e9ee1df Lacto-N-neofucopentaose LNnFP 1A BIOOLIGO bGSL:a29120da-c33d-4e34-870c-29fc14f5692e Lacto-N-neooctaose LNnO 1A BIOOLIGO bGSL:f8d8e128-594b-478f-a92a-3ba2f28378ea Lacto-N-Neotetraose Neolactotetrose LNnT 1A G48059CD GLYCOEPITOPE; SUGARBIND; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV bGSL:ae0c9f6f-750a-407c-aa2a-6e3cbd287f64 Lacto-N-triose 1A BIOOLIGO bGSL:b684bf31-47cf-467e-aab7-00676e00789a Lactogangliotetraosylceramide 1A G62554JH; G85237WB GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:2727ede0-f7ea-4a22-b081-370fc72d61fd lactosylceramide LacCer; CDH LacCer; Lc2 1A G84224TW; G20420WT; G74621DY GSD:00097 GlycoMotif:GGM.000064; GlycoMotif:CCRC.000064; GlycoMotif:GDV.000039 GSD_GLYGEN_V1; EOG_VARKI_4E; CUMMINGS; GLYCOEPITOPE; SUGARBIND; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV Glycosphingolipids which contain as their polar head group a lactose moiety bound in glycosidic linkage to the hydroxyl group of ceramide. Their accumulation in tissue, due to a defect in lactosylceramide beta-galactosidase, is the cause of lactosylceramidosis.[MeSH:D007790] In the 1970s, a neutral glycosphingolipid lactosylceramide (LacCer) was found to bind specifically to several kinds of microorganisms.[PMID:30175814] bGSL:166477ba-d959-4bc5-9d5c-d893f1de3235 Lc3 Glucocerebroside; glucoceramide; Lc_3; Lactotriaosylceramide LC3; Lc(3)Cer; Lc_3 Glucosylceramide 1A G71142DF; G06239NA; G87727XV GSD:00073; GSD:00098 GlycoMotif:GGM.000060; GlycoMotif:GGM.000067; GlycoMotif:CCRC.000067; GlycoMotif:GDV.000082; GlycoMotif:GDV.000083 GSD_GLYGEN_V1; EOG_VARKI_4E; CUMMINGS; SUGARBIND; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE Cerebrosides which contain as their polar head group a glucose moiety bound in glycosidic linkage to the hydroxyl group of ceramides. Their accumulation in tissue, due to a defect in beta-glucosidase, is the cause of Gaucher's disease.[MeSH:D005963] Glucosylceramide (GlcCer), the initial GSL synthesized from ceramide by GCS (GlcCer synthase), is required for embryonic survival, but its role in the lung is unknown.[PMID:31265321] bGSL:b50dcc9f-4dd2-44ba-8d81-b75337c1ee85 Lc4 Lactotetraosylceramide Tetraosylceramide; Lewis c 1A G00049MO PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; GLYCOEPITOPE; SUGARBIND; PUBDICT_GLYCAN_MOTIF bGSL:31182838-1fee-4b19-8295-047b12231656 LcGg4 1A G62554JH; G85237WB GSD:00099 GlycoMotif:GGM.000075; GlycoMotif:CCRC.000075; GlycoMotif:GDV.000068 GSD_GLYGEN_V1; CUMMINGS; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF N-[(2S,3R,4R,5R,6R)-2-[(2R,3S,4R,5R,6S)-4-[(2S,3R,4R,5S,6R)-3-Acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-5-hydroxy-2-(hydroxymethyl)-6-[(2R,3S,4R,5R,6R)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxan-3-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]acetamide is an oligosaccharide.[CHEBI:152521] Murine leukemia cells (M1), in their undifferentiated state, have been characterized by the presence of cancer-associated lactoganglio-series glycolipids, one of which was identified as lactogangliotetraosylceramide (LcGg4) having a novel branching at the II-Gal of lactosylceramide through GlcNAc beta 1----3 and GalNAc beta 1----4 linkage, as shown below (Kannagi, R., Levery, S.B., and Hakomori, S. (1984) J. Biol. Chem., 259, 8444-8451): GalNAc beta 1----4 Gal beta 1----4Glc beta 1----1Cer GlcNac beta 1----3 [PMID: 3805024] bGSL:2fd9fcaa-6aa1-488d-b3de-a368c74c8529 Lewis a Lewis a (Lea-3); Lewis a triose Le(a); Le^a; Lea; Lea-3 Lewis a (Lea-5) 1A G00047MO; G39023AU GSD:00100 GlycoMotif:GGM.000020; GlycoMotif:CCRC.000020; GlycoMotif:GDV.000026 GSD_GLYGEN_V1; EOG_VARKI_4E; CUMMINGS; GLYCOEPITOPE; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; PUBDICT_MOTIF_GTC; PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV; SUGARBIND; BIOOLIGO A lewis blood group antigen with structure beta-D-Galp-(1->3)-[alpha-L-Fucp-(1->4)]-D-GlcpNAc consisting of N-acetylglucosamine having a fucosyl residue attached at the 4-position via an alpha-linkage and a galactosyl residue attached at the 3-position via a beta-linkage. It has a role as an epitope and an antigen. It is an amino trisaccharide and a glucosamine oligosaccharide.[CHEBI:62265] Regardless of the vaccine administered, significantly fewer of the children with Lewis A phenotype (0/14) seroconverted after receiving the first vaccine dose compared to 26% (45/175) of those with the Lewis B phenotype and 32% (15/47) of the Lewis negative individuals (P < 0.01). [PMID:29367698] bGSL:214c9a18-6e91-48a7-92c9-19f8f414d827 Lewis a (b1-3)Gal 1A G28420BK GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:9d680e3b-dcc0-405e-b1be-b79f673f04eb Lewis a (Lea-5) Lea-5 Lewis a 1A G26123AX SUGARBIND TRUE bGSL:22e50ee4-c9db-43d6-9934-336cdf33bf75 Lewis a - Lewis x Lewis a- Lewis x Hybrid Antigen LeALex 1A G07357YR BIOOLIGO; GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV bGSL:095dc9c5-172f-4bf4-9160-55fd21ffce92 Lewis a LN 1A BIOOLIGO bGSL:ca54b8a0-e947-415a-b938-2fbf65775b55 Lewis a/x-like structure 1A G24566OP PUBDICT_GLYCAN_MOTIF bGSL:868a9f35-474f-4d77-97ec-61c9777e309a Lewis b blood group H - Lewis a; Lewis(b); Lewis b tetraose Le(b); Le^b; Leb; Leb-4 Lewis b/y-like structure trifucosyl Lewis b; Lewis b (Leb-6); Lewis b (Leb-5) 1A G39211DH; G00048MO GSD:00101 GlycoMotif:GGM.000021; GlycoMotif:CCRC.000021; GlycoMotif:CCRC.000048; GlycoMotif:GDV.000004; GlycoMotif:GDV.000013 GSD_GLYGEN_V1; EOG_VARKI_4E; CUMMINGS; GLYCOEPITOPE; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; PUBDICT_MOTIF_GTC; SUGARBIND; BIOOLIGO Lewis b is a fucosylated type 1 chain glycan epitope, with the structure Fucα1-2Galβ1-3(Fucα1-4)GlcNAc, and is known as the Lewis b antigen. Human mannose-binding lectin preferentially binds to human colon adenocarcinoma cell lines expressing high amount of Lewis A and Lewis B antigens.[PMID:10328552] bGSL:56c8577b-f0e0-4307-b438-fe115b8d5748 Lewis b (Leb-5) Lewis b pentaose Lewis b 1A G14300ZJ BIOOLIGO TRUE bGSL:d587e8af-793c-4f38-911b-28de09f68325 Lewis b (Leb-6) Lewis b hexaose Leb-6 Lewis b 1A G09552LA SUGARBIND TRUE bGSL:f425d4c7-0d6b-4fb9-ac60-e0d1b64aa58b Lewis b/y-like structure Lewis b/y Like Lewis b; Lewis y 1A G20009SF PUBDICT_GLYCAN_MOTIF bGSL:86e6290d-78b7-5b63-bff3-6f0b6ac04797 Lewis c Precursor Lewis a Precursor Lea; Lec Lc4 1A G23041XK SUGARBIND; PUBDICT_GLYCAN_MOTIF; PUBDICT_MOTIF_GTC; BIOOLIGO; PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV bGSL:58dd1d22-352a-4285-932e-106e4edec245 Lewis c - Lewis x Lec-LeX 1A PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV bGSL:a213cc92-50f8-42c3-9111-007c8d753f1b Lewis d Lewis D LeD blood group H type 1 1A G00050MO PUBDICT_GLYCAN_MOTIF; PUBDICT_MOTIF_GTC bGSL:f8b6f54b-f9bf-4551-b499-159ab46b6d82 Lewis x Lex; Le^x; Lewis x triose Le(X); Le^x; Lex; Lex-3 6-sulfo-Lewis x; Internal Lewis x; Lewis x (Lex-5); 3'-sulfo Lewis x; Lewis x (Lex-4); Lewis x (Lex-6) SSEA-1 1A G00051MO; G01187XC GSD:00102 GlycoMotif:GGM.000018; GlycoMotif:CCRC.000018; GlycoMotif:GDV.000036 GSD_GLYGEN_V1; EOG_VARKI_4E; CUMMINGS; GLYCOEPITOPE; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; PUBDICT_MOTIF_GTC; PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV; BIOOLIGO; SUGARBIND A Lewis blood group antigen with structure α-L-Fucp-(1→3)-[β-D-Galp-(1→4)]-D-GlcpNAc where the glucosamine at the reducing end has β-configuration at its anomeric centre. Commonly known as Lewis x trisaccharide or Lex.[CHEBI:59294] In particular, the observation of oxonium ions at m/z 512.2 and 803.2 is useful for probing outer non-reducing terminal fucosylation, which represented carbohydrate structures consisting of Hex Hex , dHex Hex , and HexNAc , and NeuNAc , Hex Hex , dHex Hex , and HexNAc , respectively, from which the Lewis X structure (Galbeta1-4(Fucalpha1-3)GlcNAc) was readily deduced.[PMID:15536627] bGSL:da73681d-b321-4d61-bca7-f234db12affa Lewis x (Lex-4) Lewis X tetraose Lewis x 1A BIOOLIGO TRUE bGSL:ba6a5f19-6b82-44ec-8094-06b254846968 Lewis x (Lex-5) Lewis x pentaose Lex-5 Lewis x 1A SUGARBIND TRUE bGSL:86b59282-eeae-49d8-8515-697d2b33033a Lewis x (Lex-6) Lewis X hexaose Lewis x di-Lewis x 1A BIOOLIGO TRUE bGSL:a708b6ef-ee4c-484f-90ee-aa733074f86b Lewis x on Core 2 1A BIOOLIGO bGSL:67a4e7e6-1f7c-4602-bb24-d0d94a7aadff Lewis y Ley; Le^y; H-Ley; H-Le^y; Lewis y tetraose Le(y); Le^y; LeY; Ley-4 blood group H type 2; Lewis b/y-like structure trifucosyl lewis y; Lewis y (Ley-5); Lewis y (Ley-6) 1A G00052MO; G49963IQ GSD:00103 GlycoMotif:GGM.000019; GlycoMotif:GGM.000045; GlycoMotif:CCRC.000019; GlycoMotif:GDV.000012; GlycoMotif:GDV.000014 GSD_GLYGEN_V1; CUMMINGS; GLYCOEPITOPE; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; PUBDICT_MOTIF_GTC; PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV; SUGARBIND; BIOOLIGO A Lewis blood group antigen which is a branched amino tetrasaccharide with structure alpha-L-Fucp-(1->2)-beta-D-Galp-(1->4)-[alpha-L-Fucp-(1->3)]-beta-D-GlcpNAc, consisting of consisting of N-acetyl-beta-D-glucosamine at the reducing end having an alpha-L-fucosyl residue attached at the 3-position and an alpha-L-fucosyl-(1→2)-beta-D-galactosyl moiety attached at the 4-position. A cancer-associated tetrasaccharide antigen which constitutes the core structure recognised by therapeutic antibody BR96. Conformational restriction around the GlcNAc residue is a key feature of its structure. It has a role as an antigen and an epitope. [CHEBI:59045]] In conclusion, Lewis y antigen and CD147 were significantly upregulated in ovarian tumors, and the altered expression of Lewis y may cause changes in CD147.[PMID:30816446] bGSL:4dfd8729-64ae-45c3-bfbf-71e2b1ced837 Lewis y (Ley-5) Lewis y pentaose Lewis y 1A BIOOLIGO TRUE bGSL:13454e74-fc94-455a-b74e-8cf14d3cc5a1 Lewis y (Ley-6) Lewis y hexaose; Lewis y (extended) / Hexasaccharide Ley-6 Lewis y LS-hexasaccharide d 1A G89659QV; G69030AU SUGARBIND; GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCAN_IMAGE TRUE bGSL:ca019b1c-be4e-454d-bcd6-f20074799b04 Lewis y - Lewis x Ley -Lex; Lewis y Lewis x 1A BIOOLIGO; PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV bGSL:84260831-6a53-4e79-adfd-67d7157ca0cf Lewis y-di-Lewis x Ley-Di-Lex 1A PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV bGSL:b7fd0865-0648-4714-812b-10eabd5a671a Lex on O-Mannose O-Mannose Le^x 1A G81516LH; G72060BE GlycoMotif:GGM.000057; GlycoMotif:CCRC.000057 CUMMINGS; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; PUBDICT_GLYCAN_MOTIF bGSL:2c942f09-d7f4-411a-bab5-d9153aad5adb LSTc 1A G72506RN SUGARBIND bGSL:a5ca68f3-0283-471d-b274-6ec6a687f9ff MECA-79 1A G22976NF PUBDICT_GLYCAN_MOTIF bGSL:f9b2156c-71aa-41d6-a332-d60a643dcf57 Monosialogangliotetraosylceramide GM1 1A G48558GR; G03277YI SUGARBIND; PUBDICT_GLYCAN_MOTIF A branched amino pentasaccharide consisting of the linear sequence β-D-Gal-(1→3)-β-D-GalNAc-(1→4)-β-D-Gal-(1→4)-β-D-Glc having a Neu5Ac residue attached to the inner galactose via an α-(2→3) linkage. The oligosaccharide of ganglioside GM1a.[CHEBI:59208] bGSL:12ae3480-ad20-4ff5-91df-7c9926d050cc monosialyl Gb5 GL-7 globoseries ganglioside; GL-7 globoseries ganglioside (SSEA-4) Gb5 Sialosyl galactosyl globoside; SSEA-4 1A G32254QI; G42784QY GSD:00106 GlycoMotif:GGM.000080; GlycoMotif:CCRC.000080; GlycoMotif:GDV.000098 GSD_GLYGEN_V1; GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; CUMMINGS; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV alpha-Neup5Ac-(2->3)-beta-D-Galp-(1->3)-beta-D-GalpNAc-(1->3)-alpha-D-Galp-(1->4)-beta-D-Galp-(1->4)-beta-D-Glcp is a linear amino hexasaccharide comprising β-D-glucose at the reducing end with at the 4-position a β-D-galactosyl-(1→3)-N-acetyl-β-D-glucosaminyl-(1→3)-α-D-galactosyl-(1→4)-β-D-galactosyl moiety, α(2→3)-sialylated at the terminal galactosyl residue.[CHEBI:62313] Thus, malignancy of MCF-7 is highly dependent on monosialyl-Gb5, and its activation of cSrc and FAK in GEM.[PMID:12401210] bGSL:fd5565b6-00aa-4b92-9024-334b40d047d2 Monosialylganglioside LSTb 1A G72506RN; G83513YI GlycoMotif:CCRC.000128; GlycoMotif:GDV.000116 CUMMINGS; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF bGSL:8df2b071-449c-4ea9-a695-be0ab138cb8f Monosulfated gangliotetraosylceramide Tetraosylceramide; Gg4 Gg4 1A G96614JE; G96596OC; G59736KH; G57796RK GlycoMotif:GGM.000066; GlycoMotif:CCRC.000066; GlycoMotif:GDV.000052 CUMMINGS; SUGARBIND; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF bGSL:f2e66855-4dd9-4280-a456-23cb4c2a069c monosulfated globopentaosylceramide Gb5 1A G80193TN; G30925QW; G57710SU GSD:00107 GlycoMotif:GGM.000072; GlycoMotif:GDV.000075 GSD_GLYGEN_V1; CUMMINGS; GLYCOMOTIF_GGM; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF Mono-sulfated globopentaosylceramide from human kidney.[PMID:2777788] bGSL:9bdbbce3-9c8b-4410-9d1d-56312dac9c73 monosulfated globotetraosylceramide Tetraosylceramide 1A G05297EK; G50866KI; G44854SQ; G87212TR GSD:00108 GlycoMotif:GGM.000073; GlycoMotif:CCRC.000073; GlycoMotif:GDV.000077 GSD_GLYGEN_V1; CUMMINGS; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF Mono-sulfated globotetraosylceramide from human kidney.[PMID:2559078] bGSL:0c818140-8f7e-4d9f-b6dc-09f2f17e1d04 N-Acetyl GM3 GM3 1A G91237TK; G15541SE GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:fe4b3034-8e5b-464b-ba96-d3384c934f8a N-Glycolyl GD3 1A G84891DZ GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:09572624-68b7-4e00-92d4-c05091ced507 N-glycolyl GM2 GM2gc GM2gc 1A G56478LD; G18221CF GSD:00112 GlycoMotif:GGM.000096; GlycoMotif:CCRC.000096; GlycoMotif:GDV.000073 GSD_GLYGEN_V1; CUMMINGS; GLYCOEPITOPE; SUGARBIND; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE (2S,4S,5R,6R)-2-[(2R,3S,4R,5R,6S)-3-[(2S,3R,4R,5R,6R)-3-Acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-5-hydroxy-2-(hydroxymethyl)-6-[(2R,3S,4R,5R,6R)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxan-4-yl]oxy-4-hydroxy-5-[(2-hydroxyacetyl)amino]-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid is a member of carbohydrates and carbohydrate derivatives.[CHEBI:151464] The monoclonal antibodies MK2-34 and MK1-16 (both IgM), which specifically detect N-glycolyl GM2 and N-acetyl GM2, respectively, were generated by immunizing mice with liposomes containing monophosphoryl lipid A, trehalose dimycolate, and the antigenic ganglioside.[PMID:3167861] bGSL:e52e70c0-2ecf-499b-802e-b082c89867cd N-Glycolyl GM3 GM3gc; GM3(NeuGc); N-glycolyl-GM3 GM3gc GM3 1A G75789AR GLYCOEPITOPE; SUGARBIND; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; PUBDICT_GLYCONAVI_NAME bGSL:d8724d6b-df9c-4149-848a-d6858c7bf214 Neolactohexosylceramide NLc6 1A G84034JH SUGARBIND; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:1fc4f614-8480-4ca4-9042-3043836199ba NeuAc(a2-6)-I antigen NeuAca2-6I 1A G37563FN SUGARBIND bGSL:06b649b8-5efa-43bc-ba2a-55fdcef68d2c NeuAca3-nLc8 1A G26036PN SUGARBIND bGSL:8d6056df-619a-4e56-8b06-72813e5515a3 NeuGc(a2-3)-I antigen NeuGca2-3I 1A G72494BI SUGARBIND bGSL:d3677b45-940d-4d4e-8d9e-832a7320791e NeuGc-GM1 II3Neu5GcGg4Cer; GM1(Gc) 1A G24034CH SUGARBIND; PUBDICT_GLYCAN_MOTIF bGSL:0eaefb0d-fc3b-4741-ba84-3a4feea0da0f nLc4 NLc4 paragloboside 1A G58896AZ; G48059CD; G40585SO PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:6889ad66-d4b1-405b-8e1e-fe40d78391d2 O-acetyl-GD3 9-O-acetyl GD3 1A G74121RX PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:c63a4500-6a48-4cf2-9357-1d32f1a886cd O-antigen O-polysaccharides; lipopolysaccharide O antigen; LPS O antigen O-PS 1A EOG_VARKI_4E The O-antigen is a repetitive glycan polymer that constitutes the outermost domain of the lipopolysaccharide (LPS) in Gram-negative bacteria. It is highly variable in structure and serves as a major determinant of antigenic diversity among bacterial strains. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch05/#:~:text=In%20%E2%80%9Clower%E2%80%9D%20eukaryotes%20and,in%20eukaryotic%20cells%20%28Chapter%209%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch03/#:~:text=LPSs%20carry%20long%20polysaccharides,diverse%20set%20of%20polymer%20structures', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch03/#:~:text=The%20polysaccharide%20may%20also%20be,and%20rhamsan%20%28S-194%29%20%28Figure%203.4F%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch03/#:~:text=Some%20polymers%20are%20known%20under,affect%20polysaccharide%20properties', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch05/#:~:text=Deoxyhexoses%20are%20often,CDP-glucose%20dehydratase', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch56/#:~:text=Chapter%2021%20discusses%20glycosylation,O-polysaccharides%20%28O-antigens%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch56/#:~:text=Chapter%2021%20discusses%20glycosylation,O-polysaccharides%20%28O-antigens%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch21/#:~:text=The%20outer%20core%20is%20more%20variable%3B,substituents%29%20per%20repeat%20unit', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch21/#:~:text=The%20formation%20of%20Kdo2%E2%80%93lipid%20A%20is,of%20two%20main%20synthetic%20strategies', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch21/#:~:text=O-PSs%20are%20repetitive,in%20the%20face%20of%20adaptive%20immunity'] bGSL:84b62823-0b34-43c8-82a3-796ef86f208d O-glycan core 0 core 0 1A G57321FI PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:cee449da-3e71-4398-b4b1-71ae5cf9cd65 O-glycan core 1 core 1; core 1 O-GalNAc glycan; core 1 O-glycan C1G extended core-1 O-glycan; truncated core 1 O-glycan 1A G00031MO; G00032MO GSD:00033 GlycoMotif:GGM.001005 GSD_GLYGEN_V1; EOG_VARKI_4E; GLYCOMOTIF_GGM; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; PUBDICT_MOTIF_GTC The core 1 O-glycan, also known as Galβ1-3GalNAcα1-O-Ser/Thr, is a disaccharide structure that forms the basic core of mucin-type O-glycans in vertebrates and some invertebrates. It consists of a galactose β1-3 linked to N-acetylgalactosamine α-linked to serine or threonine residues on proteins. This structure is the most common O-GalNAc glycan, generated by the enzyme C1GALT1 (T-synthase), and serves as a precursor for further elongation and modification, including sialylation and sulfation, in O-glycosylation. O-glycans are initiated by the addition of GalNAc to serine or threonine (via the ppGalNAcT family of glycosyltransferases), forming the Tn antigen (GalNAcα-O-Ser/Thr), which is used to generate the core 1 structure (Galβ1,3GalNAcα-O-Ser/Thr) on which most complex and branched O-glycans are derived. [PMID:31645367] bGSL:51b6d9e4-a15f-4af2-81a8-b99a001046fc O-glycan core 2 core 2; core 2 O-GalNAc glycan; core 2 O-glycan O-glycan SLex on Core 2 O-glycan; a-Galactose on Core 2; beta-galactosylated core 2; disialyl Core 2 1A G00033MO; G00034MO GSD:00034 GlycoMotif:GGM.001007 GSD_GLYGEN_V1; EOG_VARKI_4E; GLYCOMOTIF_GGM; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; PUBDICT_MOTIF_GTC; BIOOLIGO The trisaccharide β-D-Gal-(1→3)-[β-D-GlcNAc-(1→6)]-D-GalNAc with α configuration at the anomeric centre of the N-acetylglucosamine residue at the reducing end.[CHEBI:62158] To investigate the biological roles of core 2 O-glycans, we produced and characterized mice deficient in one or more of the three known glycosyltransferases that generate core 2 O-glycans (C2GnT1, C2GnT2, and C2GnT3).[PMID: 19349303] bGSL:7b554d4c-8a42-46bb-9967-e875c8ab657e O-glycan core 3 core 3; core 3 O-GalNAc glycan; core 3 O-glycan O-glycan 1A G00035MO; G00036MO GSD:00035 GlycoMotif:GGM.001009 GSD_GLYGEN_V1; EOG_VARKI_4E; GLYCOMOTIF_GGM; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; PUBDICT_MOTIF_GTC An amino disaccharide comprising an N-acetyl-β-D-glucosamine residue linked (1→3) to an N-acetyl-β-D-galactosamine residue at the reducing end.[CHEBI:71344] Mechanically, we revealed that mucin-type core 3 O-glycan was synthesized at the membrane-tethered MUC1 N terminus because of core 3 synthase expression in colon cancer cells.[PMID: 28745318] bGSL:1b860060-4f64-4bec-8373-bfb66460bbd4 O-glycan core 4 core 4; core 4 O-GalNAc glycan; core 4 O-glycan O-glycan 1A G00037MO; G00038MO GSD:00036 GlycoMotif:GGM.001011 GSD_GLYGEN_V1; EOG_VARKI_4E; GLYCOMOTIF_GGM; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; PUBDICT_MOTIF_GTC; BIOOLIGO A branched amino trisaccharide comprising an N -acetyl-α-D-galactosamine residue at the reducing end, to which are (1→3)- and (1→6)-linked two N -acetyl-α-D-glucosamine residues.[CHEBI:71341] The results confirm the predicted existence of a beta1,6GlcNAc-transferase that functions in both core 2 and core 4 O-glycan branch formation.[PMID: 9988682] bGSL:c7d3f855-7aa5-435f-bb21-237d0d6c7f06 O-Glycan core 5 core 5 1A G00039MO; G00040MO GlycoMotif:GGM.001013 GLYCOMOTIF_GGM; PUBDICT_GLYCAN_MOTIF; PUBDICT_MOTIF_GTC; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:7cb3a3b6-39a5-474e-b089-e1f141219aba O-Glycan core 6 core 6 1A G00041MO; G00042MO GlycoMotif:GGM.001015 GLYCOMOTIF_GGM; PUBDICT_GLYCAN_MOTIF; PUBDICT_MOTIF_GTC; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:fbf52c46-b51e-40e1-bdbc-1a2762982da7 O-Glycan core 7 1A G00043MO; G00044MO GlycoMotif:GGM.001017 GLYCOMOTIF_GGM; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; PUBDICT_MOTIF_GTC bGSL:583fed36-e40a-4a19-91f3-cd5980ccbc67 O-Glycan core 8 core 8 1A G76355TG GlycoMotif:GGM.001032 GLYCOMOTIF_GGM; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:bfdaf032-1243-46c3-8938-dc4f39e0155d O-mannose core M1 core M1; core M1 O-mannose glycan M1 O-mannose glycan / mammalian; O-mannose core 1A G85856KC EOG_VARKI_4E; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE Core M1 O-mannose glycan is one of the three main core structures (M1–M3) of O-mannose glycans, characterized by the addition of a single N-acetylglucosamine (GlcNAc) in β1-2 linkage to a protein-linked mannose. This core structure is generated by the action of POMGNT1 and can be further extended by various glycosyltransferases, representing a specific and conserved oligosaccharide core in O-mannosylation. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch13/#:~:text=Biosynthetic%20pathway%20of%20O-mannose,and%20sialyltransferases', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch13/#:~:text=Core%20M1%20glycans%20can%20be%20further,that%20adds%20%CE%B21-3GalNAc%20to%20the%20GlcNAc'] ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch45/#:~:text=O-Man%20glycan%20biosynthetic%20pathway.,DPM2%2C%20and%20DPM3%20for%20Dol-P-Man%5D%29'] bGSL:6a5b8141-d2c0-4292-8377-119b8a10955c O-mannose core M2 core M2; core m2; core M2 O-mannose glycan M2 2,6-branched O-mannose; O-mannose glycan / mammalian; O-mannose core 1A G56868BH EOG_VARKI_4E; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE Core M2 O-mannose glycan is a type of O-mannose glycan core structure characterized by the addition of two N-acetylglucosamines (GlcNAc) to a protein-linked mannose via β1-2 and β1-6 linkages. This structure is formed from core M1 through the action of MGAT5B and can be further extended by various glycosyltransferases. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch13/#:~:text=Biosynthetic%20pathway%20of%20O-mannose,and%20sialyltransferases', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch13/#:~:text=Core%20M1%20glycans%20can%20be%20further,that%20adds%20%CE%B21-3GalNAc%20to%20the%20GlcNAc'] bGSL:8ed96585-0b30-404d-bcfd-756b101eb8fe O-mannose core M3 core M3; core M3 O-mannose glycan M3 O-mannose glycan / mammalian; O-mannose core 1A G97041TX EOG_VARKI_4E; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE The core M3 O-mannose glycan is one of the three main core structures (M1–M3) of O-mannose glycans, representing a specific conserved oligosaccharide core found on mammalian α-dystroglycan. It serves as a priming substrate for the addition of repeating disaccharide units (Xyl-α3-GlcA-β3-)n, a process catalyzed by the LARGE1 or LARGE2 glycosyltransferases. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch13/#:~:text=This%20action%20serves%20to%20prime%20the,have%20disaccharide-modified%20Hyl'] ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch45/#:~:text=O-Man%20glycan%20biosynthetic%20pathway.,DPM2%2C%20and%20DPM3%20for%20Dol-P-Man%5D%29'] ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch13/#:~:text=This%20disaccharide%20is%20a%20substrate,%28or%20LARGE2%29%20glycosyltransferase', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch13/#:~:text=Core%20M1%20glycans%20can%20be%20further,that%20adds%20%CE%B21-3GalNAc%20to%20the%20GlcNAc'] bGSL:874ce2d8-fef9-53e5-b1be-e3e0be476563 P antigen GLOB P antigen Gb4 1A G00061MO GSD:00070 GlycoMotif:GGM.000070; GlycoMotif:CCRC.000070 GSD_GLYGEN_V1; EOG_VARKI_4E; GLYCOMOTIF_CCRC; PUBDICT_GLYCAN_MOTIF; PUBDICT_MOTIF_GTC An amino tetrasaccharide consisting of 2-acetamido-2-deoxy-β-D-galactopyranosyl, α-D-galactopyranosyl, β-D-galactopyranosyl, and β-D-glucopyranose units joined together in sequence by (1→3), (1→4), and (1→4) glycosidic linkages, respectively.[CHEBI:145578] Here we report that PUGNAc treatment provokes globotetraosylceramide (Gb4Cer) accumulation in human umbilical vein endothelial cells (HUVEC).[PMID:28392398] bGSL:3d6b0bbe-b769-4ad0-af43-391a402a0767 P1 antigen P1; P1 determinant; P1 penta 1A G12460DL; G00060MO; G00076PK; G55205ZV GSD:00122 GlycoMotif:GGM.000069; GlycoMotif:CCRC.000069; GlycoMotif:GDV.000024 GSD_GLYGEN_V1; EOG_VARKI_4E; CUMMINGS; GLYCOEPITOPE; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; PUBDICT_MOTIF_GTC; PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV An amino pentasaccharide consisting of α-D-galactose, β-D-galactose N-acetyl-α-D-glucosamine, β-D-galactose, and β-D-glucose residues joined in sequence with ((1→4)-, (1→4)-, (1→3)- and (1→4)-linkages, respectively.[CHEBI:68484] The P1 antigen was disovered in 1927 by Landsteiner and Levine, and Pk and NOR were described in 1951 and 1982, respectively.[PMID: 24046920] bGSL:46d00a4b-fdca-44b3-beba-d5bcf23f1330 P1 tetra 1A PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV TRUE bGSL:ea01c13b-5880-4ef1-bb4f-f7dcaf48259e P1 tri 1A PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV TRUE bGSL:0a4e1034-4c6d-4c10-a79c-d84072ed115c Para-Forssman glycolipid Para-Forssman 1A G51699SI; G98848EU GSD:00123 GlycoMotif:GGM.000085; GlycoMotif:CCRC.000085; GlycoMotif:GDV.000066 GSD_GLYGEN_V1; CUMMINGS; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF GalNAcβ1→3GalNAcβ1→3Galα1→4Galβ1→4Glcβ1→1Cer [https://doi.org/10.1016/S0040-4039(01)93814-6] A novel pentaglycosyl ceramide containing di-beta-N-acetylgalactos-aminyl residue (Para-Forssman glycolipid) isolated from human erythrocyte membrane. [PMID:6814203] bGSL:775021d3-ef13-41d6-93e2-5f73b8487c69 Para-Lacto-N-neohexaose 1A BIOOLIGO bGSL:d062f609-c8bb-42fe-980d-5a89645ce295 paragloboside nLc4 1A G58896AZ; G48059CD; G40585SO GSD:00124 GlycoMotif:GGM.000077; GlycoMotif:CCRC.000077; GlycoMotif:GDV.000043 GSD_GLYGEN_V1; CUMMINGS; GLYCOEPITOPE; SUGARBIND; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE α-Neup5Ac-(2→3)-β-D-Galp-(1→3)-D-GalpNAc in which the configuration at the GalNAc anomeric carbon is α.[CHEBI:65257] bGSL:6139c5f4-ce76-496e-9462-a2fe2d58058b Pk antigen P^k antigen; Pk Gb3 1A G00059MO; G06000DZ GSD:00175 GlycoMotif:GGM.000068; GlycoMotif:CCRC.000068; GlycoMotif:GDV.000023 GSD_GLYGEN_V1; EOG_VARKI_4E; CUMMINGS; GLYCOEPITOPE; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; PUBDICT_MOTIF_GTC; PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV Related synonym extracted from gsdv1 edge. See edges.jsonl for the linked subject term. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch31/#:~:text=Interaction%20between%20prototype,Pk%20and%20P%20antigens%20%28Chapter%2014%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch31/#:~:text=This%20lectin%20domain%20was%20found%20to,it%20with%20other%20functional%20domains'] ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch31/#:~:text=Interaction%20between%20prototype,Pk%20and%20P%20antigens%20%28Chapter%2014%29'] bGSL:50302e10-77bb-4b33-9013-39303ad450bf polysaccharide A 1A EOG_VARKI_4E Polysaccharide A (PSA) is a capsular polysaccharide characterized by zwitterionic properties. It is notable for its immunomodulatory role and its involvement in the maturation of the immune system. Polysaccharide A is distinct from polysialic acids. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch21/#:~:text=EPSs%20may%20also%20aid%20in%20health,of%20plant%20pathogens%20and%20symbionts'] bGSL:7a68c41a-8377-49fb-bb94-2e39d5725499 SD1a 1A G63813EJ GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:cd35a87e-6d05-4c0b-a968-618c445f9069 Sda antigen Sda/CT antigen; Sd^a/CT antigen; CT/Sda; Sda blood group antigen Sd(A); Sda 1A G41052GC; G00062MO GSD:00164 GlycoMotif:GGM.000051; GlycoMotif:CCRC.000051; GlycoMotif:GDV.000086 GSD_GLYGEN_V1; EOG_VARKI_4E; PUBDICT_GLYCAN_MOTIF; PUBDICT_MOTIF_GTC; CUMMINGS; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV A branched amino tetrasaccharide comprised of a trisaccharide chain of N-acetyl-α-neuraminic acid, β-D-galactose and N-acetyl-β-D-glucosamine residues linked sequentially (2→3) and (1→4), to the galactose residue of which is also linked (1→4) an N-acetyl-β-L-galactosamine residue. [CHEBI:71561] The expanding roles of the Sd(a)/Cad carbohydrate antigen and its cognate glycosyltransferase B4GALNT2.[PMID:24112972] bGSL:afdd6b64-2ea6-4f87-b34b-de4358df0dfb seminolipid 1A G72548RZ; G95090DW GSD:00127 GlycoMotif:GGM.000062; GlycoMotif:GDV.000050 GSD_GLYGEN_V1; CUMMINGS; SUGARBIND; GLYCOMOTIF_GGM; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF A concise total synthesis of seminolipid, a sulfoglycolipid, has been achieved; key features include regioselective, tin-free sulfation of allyl β-d-galactopyranoside using 2,6-bis(trifluoromethyl)phenylboronic acid as protective reagent, stereoselective epoxidation, and site-selective acylation. [PMID: 31353379] bGSL:fee20ed7-6b20-42fb-90f5-486e7b300a8f Sia2TF 1A BIOOLIGO bGSL:7a3f8810-69e0-5a62-8171-541fa27f5c6f Sialosyl galactosyl globoside Sialosyl gal-globoside SGG monosialyl Gb5 1A G32254QI SUGARBIND; PUBDICT_GLYCAN_MOTIF bGSL:04d041f2-8d38-4080-822e-175af25879ed sialosyl paragloboside NeuAca3SPG; NeuAca2-3PG; IV3(NeuAc)nLc4Cer; S-3-PG; S3P; Sial pg S2-3PG; S3P; S-3-PG; Sial pg Siaα2-3Galβ1-4GlcNAc 1A G50123ZO; G01767JJ; G98750DB; G00065MO GSD:00129 GlycoMotif:GGM.000081; GlycoMotif:CCRC.000081; GlycoMotif:GDV.000114; GlycoMotif:GDV.000120 GSD_GLYGEN_V1; CUMMINGS; GLYCOEPITOPE; SUGARBIND; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE α-Neup5Ac-(2→3)-β-D-Galp-(1→4)-D-GlcpNAc with β configuration at the anomeric position of the reducing-end N-acetyl-D-glucosamine residue.[CHEBI:71612] Unlike CNS myelin, human peripheral nerve myelin has the acidic glycosphingolipids sialosyl paragloboside (SPG), sialosyl lactosaminyl paragloboside (SLPG), and sulfated glucuronyl paragloboside (SGPG).[PMID:8862128] bGSL:e0e18800-1f48-4233-9aaf-8004103b947f sialyl Lewis a sialyl-Lea; NeuAca3-Lea SLea; SLe^a; sLea sialyl-Lewis a/x-like; sialyl-Lewis a glycolipid disialyl-Lewis a CA19-9 1A G00053MO; G50321QR; G91326YS; G81971FM; G16258KS GSD:00130 GlycoMotif:GGM.000024; GlycoMotif:CCRC.000024; GlycoMotif:GDV.000090 GSD_GLYGEN_V1; EOG_VARKI_4E; CUMMINGS; GLYCOEPITOPE; SUGARBIND; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; PUBDICT_MOTIF_GTC; BIOOLIGO A sialyated version of Lewis A with a branched structure of amino tetrasaccharide consisting of a sialyl residue, linked (2→3) to a galactosyl residue that in turn is linked (1→3) to a glucosaminyl residue at the reducing end, which is also carrying a fucosyl residue at the 4-position.[CHEBI:62681] By comparing the serum O-glycan profiles from healthy controls with those of cancer patients, we identified a marker candidate, core 1 sialyl Lewis A (NeuAcα2-3Galβ1-3(Fucα1-4)GlcNAcβ1-3Gal) (abbreviated C1SLA), whose concentration appeared to be weakly correlated with CA19-9 values.[PMID:26641888] bGSL:a2d27164-5558-4851-96aa-4069c7c5b7c1 sialyl Lewis c SaiLec SLec; SaiLec disialyl-Lewis c 1A G46776WR GLYCOEPITOPE; SUGARBIND; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:d351c5a2-3af1-4e8c-b831-5e45fb62e858 sialyl Lewis x sialyl-Lex; NeuAca3-Lex; SaiLex; Slex; SLe^x SLe(x); SLe^x; SLex; sLex; SaiLex sialyl-Lewis a/x-like 6,6'-dissulfo sialyl Lewis X; sialyl Lewis x-i antigen; 6-sulfo-sialyl-Lewis x; sialyl Lewis x (sLex-5) 1A G00054MO; G96401FK GSD:00131 GlycoMotif:GGM.000022; GlycoMotif:CCRC.000022; GlycoMotif:GDV.000105 GSD_GLYGEN_V1; EOG_VARKI_4E; CUMMINGS; GLYCOEPITOPE; SUGARBIND; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; PUBDICT_MOTIF_GTC A sialylated version of Lewis X antigen expressed on cell surfaces with structure alpha-Neup5Ac-(2->3)-beta-D-Galp-(1->4)-[alpha-L-Fucp-(1->3)]-beta-D-GlcpNAcis α-Neup5Ac-(2→3)-β-D-Galp-(1→4)-[α-L-Fucp-(1→3)]-D-GlcpNAc in which the anomeric configuration of the reducing-end N-acetyl-beta-D-glucosamine residue is beta. It is a ligand for selectins. [MESH:2030970,CHEI:71622] As sialyl Lewis X is a lignad of the selectin family, it has been proposed that sialyl Lewis X-rich colon cancer cells metastasize to the liver by adhesion to selectins on hepatic endothelial cells.[PMID:12828079] bGSL:21951ada-f6ca-402b-bb80-4076f7d0d55d sialyl Lewis x (sLex-5) Sialyl Lewis X (sLeX) pentaose sialyl Lewis x 1A BIOOLIGO TRUE bGSL:47f49cb3-0530-4575-ab6c-e24173f0d5e2 sialyl Lewis x - Lewis x NeuAca3-dimer-Lex; sialyl-di-Lewis x SDLex; SDLe^x; Slex-Lex 1A G45215IJ; G19619KS; G69360KJ GlycoMotif:GGM.000032; GlycoMotif:CCRC.000032; GlycoMotif:GDV.000103 SUGARBIND; PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV; CUMMINGS; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; BIOOLIGO bGSL:11b192df-d57a-4a46-ad21-2df68f44c237 sialyl Lewis x-i antigen sialyl Lewis x 1A G06597DS; G93855LZ GSD:00158 GSD_GLYGEN_V1; GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE Univariate analysis showed that survival of NSCLC patients with high (more than 100 units/ml) sialyl Lewis X-i antigen levels was significantly poorer than that of patients with low antigen levels (P = 0.0001).[PMID:9815711] bGSL:e5d24073-b945-486a-b727-4204eb7d337e sialyl T antigen sialylated O-GalNAc glycan; T antigen 1A G65562ZE; G56299XO GSD:00132 GlycoMotif:GGM.000013; GlycoMotif:CCRC.000013; GlycoMotif:GDV.000097 GSD_GLYGEN_V1; CUMMINGS; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF Alpha-Neup5Ac-(2→3)-beta-D-Galp-(1→3)-alpha-D-GalpNAc is alpha-Neup5Ac-(2→3)-beta-D-Galp-(1→3)-D-GalpNAc in which the configuration at the GalNAc anomeric carbon is alpha. It has a role as an epitope.[CHEBI:65257] The expression and functional analysis of the sialyl-T antigen in prostate cancer.[PMID:32583304] bGSL:bc2960cd-1dab-5ae3-9b36-9b4d46d7c292 sialyl Tn antigen sialyl-Tn antigen sTn; sTn antigen; STn 6-sialyl GalNAc 1A G36123IU; G08371CD; G38301SX GSD:00137 GlycoMotif:GGM.000012; GlycoMotif:CCRC.000012; GlycoMotif:GDV.000117 GSD_GLYGEN_V1; EOG_VARKI_4E; CUMMINGS; GLYCOEPITOPE; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; PUBDICT_GLYCONAVI_NAME N-acetyl-alpha-neuraminyl-(2→6)-N-acetyl-alpha-D-galactosamine is an N-acetyl-alpha-neuraminyl-(2→6)-N-acetyl-D-galactosamine in which the carbon bearing the anomeric hydroxy group has alpha configuration. It has a role as an epitope. It derives from a N-acetyl-alpha-D-galactosamine and a N-acetyl-alpha-neuraminic acid.[CHEBI:61818] The interaction between Siglec-15 and tumor-associated sialyl-Tn antigen enhances TGF-β secretion from monocytes/macrophages through the DAP12-Syk pathway.[PMID:23035012] bGSL:6ddbe4a3-6220-4c6b-904a-75eb6bd07e80 sialyl-Lewis a glycolipid Sialyl Leaglycolipid sialyl Lewis a 1A G50321QR; G91326YS GlycoMotif:GDV.000089; GlycoMotif:CCRC.000127 GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; CUMMINGS; GLYCOMOTIF_CCRC TRUE bGSL:edb81811-0183-4ea0-b07c-1608a1ea39f9 sialyl-Lewis a/x-like sialyl Lewis x; sialyl Lewis a 1A G25705KO PUBDICT_GLYCAN_MOTIF bGSL:42941d5c-b161-4a65-8f14-c585754fdf87 sialyl-Lewis x - Lewis x- Lewis x SLex-Lex-Lex 1A BIOOLIGO bGSL:ec727c41-12bf-4b03-bdce-f598c3483478 Sialyllactotetraosylceramide sialopentaosylceramide α(2-6)sialylÂ_ lactotetraosylceramide 1A G72692DY; G79536OW SUGARBIND; PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV bGSL:d4cf5ec6-1f0b-43f8-b32e-14b369755c4b SLex on Core 2 O-glycan SLe^x Core 2 O-glycan O-glycan core 2 disialyl Core 2 with sLex on Core 2 1A G97345NY; G71121NN GlycoMotif:GGM.000053; GlycoMotif:CCRC.000053; GlycoMotif:GDV.000106 CUMMINGS; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; BIOOLIGO bGSL:34fdd11c-a17a-44da-a2d1-65619956dea7 SM3 1A G20044TD GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:fb8b1337-5200-4df8-b7d3-58d8b18dfdee SM4s 1A G72548RZ GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:e2555445-ede1-5eda-babd-8a67c39f9fd0 SSEA-1 SSEA Lewis x 1A G85497PI; G01187XC GSD:00138 GlycoMotif:GDV.000038 GSD_GLYGEN_V1; GLYCOEPITOPE; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE Our findings suggest that expression of SSEA-1 immunoreactivity in thyroid neoplasms was associated with more aggressive thyroid carcinomas.[PMID:27550342] bGSL:1cb412d7-4818-42d8-a7b3-452350ca4bae SSEA-3 Stage-specific embryonic antigen-3 SSEA-3 SSEA Gb5 1A G25129BT; G99053DY; G19298OA GSD:00139 GlycoMotif:GGM.000079; GlycoMotif:CCRC.000079 GSD_GLYGEN_V1; CUMMINGS; GLYCOEPITOPE; SUGARBIND; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE An amino trisaccharide consisting of β-D-galactopyranose, 2-acetamido-2-deoxy-β-D-galactopyranose and α-D-galactopyranose residues joined in sequence by (1→3) glycosidic linkages.[CHEBI:149071] Glycosphingolipids (GSLs), such as the globo-series GSLs stage-specific embryonic antigen 3 (SSEA-3), SSEA-4, and Globo-H, are specifically expressed on pluripotent stem cells and cancer cells, and are known to be associated with various biological processes such as cell recognition, cell adhesion, and signal transduction.[PMID:31817926] bGSL:76715d86-4d40-5851-a7dd-75ebd8fdfb4e SSEA-4 stage-specific embryonic antigen-4; Stage specific embryonic antigen-4 SSEA monosialyl Gb5 1A G84263XI; G32254QI GSD:00140 GSD_GLYGEN_V1; EOG_VARKI_4E; GLYCOEPITOPE; SUGARBIND; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV SSEA-4 is a glycosphingolipid (ganglioside) known as stage-specific embryonic antigen-4, which serves as a marker for embryonic stem cells and cancer stem cells. Glycosphingolipids (GSLs), such as the globo-series GSLs stage-specific embryonic antigen 3 (SSEA-3), SSEA-4, and Globo-H, are specifically expressed on pluripotent stem cells and cancer cells, and are known to be associated with various biological processes such as cell recognition, cell adhesion, and signal transduction.[PMID:31817926] bGSL:f96ffc51-e163-5e73-a3d2-3da4a5944235 Sulf-lactosylceramide ceramide dihexosyl sulfate 1A G20044TD SUGARBIND bGSL:a966d9d1-168f-4fb3-8cb0-dbc2f17417ef sulfatide 1A G72548RZ; G07169WN; G60011XD; G40843KY; G95090DW GSD:00142 GlycoMotif:GGM.000063; GlycoMotif:CCRC.000063; GlycoMotif:GDV.000051 GSD_GLYGEN_V1; EOG_VARKI_4E; CUMMINGS; SUGARBIND; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCONAVI_NAME A glycosphingolipid composed of a galactosylceramide (GalCer) molecule with a sulfate group attached, commonly found in myelin and various other tissues. In a previous study we found that sulfatide was efficient in lowering HIV-1 viral loads in SCID mice engrafted with human fetal liver/thymus tissues (SCID-hu).[PMID:23550344] bGSL:7500d04a-76b6-4c32-97f0-89d923dc49ca Sulfo Lewis X 6-sulfo-Lewis x; 3'-sulfo Lewis x; 4'-sulfo-Lewis x 1A BIOOLIGO bGSL:e60051d2-d6ef-4697-84b9-de7057187160 Sulfo-isogloboside Mono-sulfated isoglobotetraosylceramide 1A G56133NW; G30925QW; G10057XH; G57036MA GlycoMotif:GGM.000074; GlycoMotif:CCRC.000074; GlycoMotif:GDV.000076 CUMMINGS; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF bGSL:e124a7cb-a421-4c34-afa1-13e150104187 T antigen TF antigen; Thomsen-Fridenreich antigen TF disialyl T antigen; sialyl T antigen 1A G00031MO; G78436BB GSD:00143 GlycoMotif:GGM.000009; GlycoMotif:CCRC.000009; GlycoMotif:GDV.000027 GSD_GLYGEN_V1; EOG_VARKI_4E; CUMMINGS; GLYCOEPITOPE; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; PUBDICT_GLYCONAVI_NAME An amino disaccharide composed of D-galactose and N-acetyl-α-D-galactosaminyl residues in β-(1→3) linkage.[CHEBI:61820] Tn, sTn, and T antigen neo- or over-expression occurs in many types of cancer including gastric, colon, breast, lung, esophageal, prostate, and endometrial cancer.[PMID:27679419] bGSL:d7eef017-1e00-4f69-bc7f-30287e769116 Tetraosylceramide monosulfated globotetraosylceramide; Monosulfated gangliotetraosylceramide; iGb4; Lc4; Gb4 1A G95034OI SUGARBIND bGSL:64c1a76a-69c2-4db9-bd36-73847cb42b4f Tn antigen Thomsen-Nouveau antigen; Tn 1A G57321FI; G61406KC GSD:00146 GlycoMotif:GGM.000008; GlycoMotif:GDV.000062 GSD_GLYGEN_V1; EOG_VARKI_4E; CUMMINGS; GLYCOEPITOPE; GLYCOMOTIF_GGM; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE Tn anitigen or alpha-galnac or N-Acetylgalactosamine is an N-acetyl-D-galactosamine having alpha-configuration at the anomeric centre. It has a role as an epitope. It derives from an alpha-D-galactosamine.[CHEBI:40356,HMDB0000212] Furthermore, we confirmed that LS174T cells (Tn-positive) transfected with wild-type Cosmc, thus expressing no Tn antigen, had down-regulation of H-Ras expression and subsequent inhibition of EMT process.[PMID:30637914] bGSL:e68ecf56-d1c8-486d-8cf1-197631a059b8 tri-Lewis x Lewis x - Lewis x - Lewis x Tri-Lex 1A BIOOLIGO; PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV bGSL:1cfed420-5366-4107-93ad-074dfe9709f0 trifucosyl Lewis b Lewis b Extended trifucosyl-Leb 1A G74578MX GSD:00150 GSD_GLYGEN_V1; GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE N-[(2R,3R,4R,5S,6R)-4-[(2R,3R,4S,5S,6R)-4-[(2S,3R,4R,5S,6R)-3-Acetamido-4-[(2R,3R,4S,5R,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-6-(hydroxymethyl)-5-[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2-hydroxy-6-(hydroxymethyl)-5-[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl]acetamide is an amino sugar.[CHEBI:153783] Extended type-1 chain glycosphingolipid antigens. Isolation and characterization of trifucosyl-Leb antigen (III4V4VI2Fuc3Lc6)[PMID:1735443] bGSL:cecbaec0-0413-40a8-bb92-9fe1f115e787 trifucosyl lewis y Lewis y 1A G74917JX GSD:00151 GSD_GLYGEN_V1; GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE A branched heptasaccharide derivative consisting of two repeating units of β-D-Gal-(1→4)-[α-L-Fuc-(1→3)]-β-D-GlcNAc (joined by a (1→3)-linkage) with an α-L-fucosyl residue attached at the 2-position of the galactose residue at the non-reducing end.[CHEBI:61332] The third, major component, common in all eight cases, has been identified as trifucosyl Ley (lactotrifucononaosylceramide, III3FucV3FucVI2FucnLc6, Structure 2 below) based on 1H NMR spectroscopy, methylation analysis, and direct-probe electron-impact mass spectrometry.[PMID:3733752] bGSL:c31b1254-56e2-4989-9349-03a5b91856a3 Trisialogangliotetraosylceramide ganglioside GT1b; NeuAc-GT1b GT1b b-series gangliosides 1A G40183QN; G05952XV GSD:00082 GlycoMotif:GGM.000112; GlycoMotif:CCRC.000112; GlycoMotif:GDV.000100 GSD_GLYGEN_V1; EOG_VARKI_4E; CUMMINGS; GLYCOEPITOPE; SUGARBIND; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV; BIOOLIGO A branched amino heptasaccharide comprising a β-D-galactosyl-(1→4)-β-D-glucose disaccharide, the galactosyl residue of which carries an N-acetyl-α-neuraminyl-(2→3)-β-D-galactosyl-(1→3)-N-acetyl-β-D-galactosaminyl trisaccharide unit and an N-acetyl-α-neuraminyl-(2→8)-N-acetyl-α-neuraminyl disaccharide unit through (2→4) and (2→3) linkages respectively. It corresponds to the carbohydrate portion of ganglioside GT1b.[CHEBI:59225] GT1b ganglioside is axonally transported to the spinal cord dorsal horn and contributes to characteristics of neuropathic pain such as mechanical and thermal hypersensitivity.[PMID: 32030804] bGSL:8d32b2de-2fc4-4eba-893f-0d40f350131d truncated core 1 O-glycan truncated core 1 structure O-glycan core 1; truncated O-GalNAc glycan; truncated O-glycan 1A EOG_VARKI_4E Truncated core 1 O-glycans are O-glycans based on the core 1 structure (Galβ1-3GalNAcα1-Ser/Thr) that are incompletely extended. Examples include the Tn antigen (GalNAcα1-Ser/Thr) and the T antigen (Galβ1-3GalNAcα1-Ser/Thr), which represent early intermediates or incomplete forms of core 1 O-glycans. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch56/#:~:text=Like%20plants%2C%20some%20insect%20cells%20may,core%201%20structures%20%28Tn%20and%20T%29'] bGSL:794ea2bf-ad02-4fff-a9c0-7a77dca72a16 VIM-2 VIM-2 1A G22418PV; G01296LJ; G00065MO GSD:00155 GlycoMotif:GGM.000033; GlycoMotif:CCRC.000033; GlycoMotif:GDV.000111 GSD_GLYGEN_V1; CUMMINGS; GLYCOEPITOPE; SUGARBIND; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; PUBDICT_MOTIF_GTC α-Neup5Ac-(2→3)-β-D-Galp-(1→4)-β-D-GlcpNAc-(1→3)-β-D-Galp-(1→4)-[α-L-Fucp-(1→3)]-D-GlcpNAc in which the anomeric configuration of the N-acetyl-D-glucosamine residue at the reducing end is β.[CHEBI:85946] Anti-SSEA-1 which binds to glycoconjugates with a Gal beta 1-4(fuc alpha 1-3)GlcNAc epitope and VIM-2 which binds to gangliosides with a NeuAc alpha 2-3GlcNAc beta-4(FUC alpha 1-3) GlcNAc beta 1-3Gal-epitope were used to determine the expression of their corresponding carbohydrate antigens in human leukocytes and leukemia cells.[PMID:1690317] bGSL:a290c74e-1c7e-42fa-b779-55fee9cdffc1 Xeno antigen type 1 1A BIOOLIGO bGSL:6c06bf69-8c27-4c25-81e1-7468fe46964f Xeno antigen type 2 1A BIOOLIGO bGSL:7385bab1-8b85-4e67-b20c-cb4b1a87c9ad Xeno lewis a 1A BIOOLIGO bGSL:dac84199-138c-4844-a15a-9d41feafc1b9 Xeno lewis X Gal Lewis X 1A BIOOLIGO bGSL:ad423f8a-abca-4757-9b79-411daf6be16a 2'-fucosyl-di-LacNAc 2'-F-Di-LN 1B BIOOLIGO bGSL:c577262e-f788-4a5f-b6bd-7c62317d4c5e 2-3 Sialyl-Lacto-N-Tetraose LSTa 1B G21066IE GLYCOEPITOPE; SUGARBIND; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; BIOOLIGO bGSL:4df9fa13-4b38-429f-8e18-ad0ddf8c5971 2-6 Sialyl-LacNAc-Gal Siaα2-6Galβ1-4GlcNAc 1B G03509EL GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:27e2a712-f19f-4fc3-8f8a-5c0f6e21e4a9 2-6-branch of complex N-glycans galactose-terminated N-glycan branch 1B EOG_VARKI_4E The 2-6-branch of complex N-glycans refers to the α1-6 core mannose that is substituted at both the 2 and 6 positions, bearing GlcNAcβ1-6 and GlcNAcβ1-2 antennae. This structure typically features a Galβ1-4GlcNAcβ1-2(Galβ1-4GlcNAcβ1-6)Manα1-R motif, representing a common branching pattern in complex N-glycans. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch48/#:~:text=A%20good%20example%20of%20this%20is%20the,%28MGAT5%20and%20-5B%29%20%28Chapter%209%29'] bGSL:bed528d3-e972-4af8-b283-02e5b5ad1a6d 2-9,2-6 Disialyllactosylceramide 1B G30187JM GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:a8d8a973-c538-4c92-b92d-f3e455340ebc 3'-GlcNAc-di-LacNAc 3'-N-acetylglucosaminyl-di-N-acetyllactosamine 3'GN-Di-LN 1B PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV bGSL:276aa746-43d1-4f66-9633-0987f1b95e8c 3'-GlcNAc-type 1 chain 3'-N-acetylglucosaminyl type 1 chain 3'GN type1 1B PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV bGSL:2704333a-5f1c-4bfc-ac90-e606297aaa36 3'-KDN-LacNAc 3'-deaminoneuraminyl-N-acetyllactosamine 3'KDNLN 1B PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV; BIOOLIGO bGSL:995593c4-1291-46d6-b3a9-0e7add9ece6d 3'-NeuGc-LacNAc 3'-N-glycolylneuraminyl-N-acetyllactosamine 3'SLN (Gc) 3'-sialyl-LacNAc (type 2) 1B PUBDICT_GLYCONAVI_NAME bGSL:2529f6b4-fff1-4fd3-8d81-d4ac3029c54d 3'-sialyl-di-LacNAc 3'-sialyl-di-N-acetyllactosamine 3'-SiaDi-LN; 3'S-Di-LN 1B BIOOLIGO; PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV bGSL:b9070842-9a92-42ba-aa45-3ea42c8792f6 3'-sialyl-LacdiNAc 3-SLDN; 3-sialyl-LacdiNAc 3'SLDN 1B PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV; BIOOLIGO bGSL:4167f02b-c603-4639-9c69-51cc0da636eb 3'-sialyl-LacNAc (type 1) 3'SiaLacNAc(1-3); 3'-sialyl-N-acetyllactosamine(1-3) 3'SiaLacNAc(1-3) sialylated N-acetyllactosamine 1B G59168YE SUGARBIND; PUBDICT_GLYCAN_MOTIF bGSL:fab91305-83ce-4263-96df-895a3d170429 3'-sialyl-LacNAc (type 2) 3-sialyl-LacNAc; 3'-sialyl-N-acetyllactosamine(1-4); 3'SiaLacNAc(1-4); sialylated triose type 2; 3'-sialyl-N-acetyllactosamine; 3-sialyl LN (type 2) 3'SiaLacNAc(1-4); 3'SLN; 3'-SLN sialylated N-acetyllactosamine; N-acetyllactosamine (type 2) Sulfated sialyl-3-N-acetyllactosamine; 3'-NeuGc-LacNAc α2-3 sialyllactosamine; Siaα2-3Galβ1-4GlcNAc 1B G10203DW; G00065MO GSD:00004 GlycoMotif:GGM.000034; GlycoMotif:CCRC.000034; GlycoMotif:GDV.000112 GSD_GLYGEN_V1; CUMMINGS; SUGARBIND; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; BIOOLIGO; PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV A linear amino trisaccharide consisting of α-neuraminyl, β-D-galactosyl and N-acetyl-D-glucosamine residues linked in a (2→3) and (1→4) sequence.[CHEBI:52472] Using new crystal structures, we also provide the atomic resolution basis for the differential recognition of 3' and 6'SiaLacNAc1–4 (with the Galβ1–4 linkage known as Type 2 backbone16; Scheme 1) by TgMIC1-MARR, and make comparisons with the Type 1 chain isomer of 3'SiaLacNAc1–4 (designated 3'SiaLacNAc1–3).[PMID:19593815] bGSL:0cafdd86-c4ae-45f1-b161-65add4a6fe15 3'-sialyl-tri-LacNAc 3'-sialyl-tri-N-acetyllactosamine 3'STri-LN 1B PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV bGSL:5a4deea0-e3fc-5f34-b347-324fb0f963c7 4'-sulfated LDN 4'-sulfo-LacdiNAc; 4-sulfated LDN; sulfated LacdiNAc LacdiNAc 1B G18464VS; G31301MT GSD:00141 GlycoMotif:GGM.000049; GlycoMotif:CCRC.000049; GlycoMotif:GDV.000078 CUMMINGS; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; PUBDICT_GLYCAN_MOTIF; GLYCOMOTIF_GDV; GSD_GLYGEN_V1 bGSL:d0e75eb3-a227-489d-9043-e29ab3e6d9cf 6'-NeuGc-LacNAc 6'-N-glycolylneuraminyl-N-acetyllactosamine 6'SLN (Gc) 6'-sialyl-N-acetyllactosamine 1B PUBDICT_GLYCONAVI_NAME bGSL:a2bf78ea-d021-4842-80be-0fbe0adc504e 6'-sialyl-di-LacNAc 6'-sialyl-di-N-acetyllactosamine 6'S-Di-LN 1B PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV; BIOOLIGO bGSL:f0a41d2c-aeb4-4301-9d99-85d31514d3f1 6'-sialyl-LacdiNAc 6'SLDN 1B PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV bGSL:b4a6921b-9683-4c07-9cdc-639a96174746 6'-sialyl-LacNAc (type 1) 6-Sialyl LN (type 1) 1B PUBDICT_GLYCAN_MOTIF bGSL:eca325be-2dcf-455f-8493-07ea22dabdda 6'-sialyl-LacNAc (type 2) 6-Sialyl LN (type 2) 1B PUBDICT_GLYCAN_MOTIF bGSL:819d5951-1e5d-4794-abf0-a0fbe6ced566 6'-sialyl-N-acetyllactosamine 6'SiaLacNAc(1-4) 6'-sialyl LN; 6'SLN; 6'SiaLacNAc(1-4) sialylated N-acetyllactosamine α2-6-sialylated 6-sulfo-LacNAc; 6'-NeuGc-LacNAc; Sialyl 6-Sulfo LacNAc 1B G09376MR SUGARBIND; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV bGSL:a4b352b6-d14a-460f-a99f-79c11c5a5f57 6'-sialyllactose 6'SL 1B PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV bGSL:5bc79069-d0e1-47d3-8a23-6305f871255e 6,6'-disulfo-LacNAc 6,6'-disulfo-N-acetyllactosamine; 6,6'-Sulfo LacNAc 6-sulfo LacNAc 1B G41392LY; G24270KX GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:985c7dcb-fb85-4ccb-82c8-8ccb60311de8 6-sulfo LacNAc α2-6-sialylated 6-sulfo-LacNAc; Sialyl 6-Sulfo LacNAc; 6,6'-disulfo-LacNAc 1B G13157WZ GSD:00159 GSD_GLYGEN_V1; GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE An oligosaccharide sulfate that is N-acetyllactosamine in which the hydroxy group at position 6 of the N-acetylglucosamine ring has been converted into its hydrogen sulfate derivative.[CHEBI:148005] In the search for an additional marker to better dissect the two subsets we have explored the marker 6-sulfo LacNAc (slan).[PMID:31572354] bGSL:1c12b1d2-e319-4f09-976b-83d6b6905def 9-O-acetyl-3'-sialyl-LacNAc 9-O-acetyl-3'-sialyl-N-acetyllactosamine 9OAc3'SLN 1B PUBDICT_GLYCONAVI_NAME bGSL:04cdfd85-a807-4407-a54e-ee9e24868ac7 ABH precursor chain type 1 type-1 chain repeating unit; type-1 unit 1B EOG_VARKI_4E A disaccharide motif consisting of galactose β1-3 linked to N-acetylglucosamine (Galβ1-3GlcNAc), known as the Type 1 chain. This structure can be repeated, serves as a scaffold for further glycan extension, and acts as a precursor for type 1 H and Lewis antigens. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch10/#:~:text=Extensions%20by%20Type%201,labile%20under%20alkaline%20conditions'] ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch14/#:~:text=The%20Lewis%20b%20antigen%20%28Leb%29%20is,same%20epithelia%20that%20express%20FUT2'] bGSL:d5e157b7-23f9-4612-a3b8-2f6d83bd5c9d ABH precursor chain type 2 type-2 chain repeating unit; type-2 unit 1B EOG_VARKI_4E The type-2 unit is a disaccharide motif consisting of galactose β1-4 linked to N-acetylglucosamine (Galβ1-4GlcNAc), which can be repeated and serves as a scaffold for further glycan extension. It acts as a minimal acceptor for glycosyltransferases, is a ligand for galectins, and forms the backbone for the synthesis of blood group H, A, B, and Lewis antigens. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch10/#:~:text=Extensions%20by%20Type%201,labile%20under%20alkaline%20conditions', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch30/#:~:text=An%20initial%20structure%20for%20the,of%20the%20nucleotide-activated%20Neu5Ac', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch32/#:~:text=Yet%2C%20in%20other%20L-type%20lectins%2C%20no,%C3%85%20%28B%29%20complexed%20with%20Gal%CE%B21-4GlcNAc', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch43/#:~:text=These%20GPI-anchored%20proteins%20form%20a,these%20are%20far%20less%20well%20studied.%20T'] ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch14/#:~:text=Blood%20group%20i%20and%20I%20antigen,glycolipids%20%28Type-4%29%20%28Figure%2014.4%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch14/#:~:text=The%20A%2C%20B%2C%20and%20H%20blood%20group,as%20modifying%20milk%20oligosaccharides'] ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch14/#:~:text=Surprisingly%2C%20there%20is%20essentially,a%20specific%20%CE%B11-3GalT%20%28Figure%2014.8%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch14/#:~:text=The%20Gal%CE%B11-3Gal%20epitope%20%28often,endothelial%20cell%20cytotoxicity'] bGSL:13ea2f8c-7ed8-41b1-8156-3d940a169105 ABH precursor chain type 4 type-4 chain blood group B type 4; blood group H type 4; blood group A type 4 1B EOG_VARKI_4E A glycan chain present in human erythrocyte glycolipids that serves as the backbone for A, B, and H blood group determinants. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch14/#:~:text=Both%20of%20these%20integral%20membrane,on%20Type-1%20units%20%28Figure%2014.4%29'] bGSL:a73941a6-ed53-408a-8139-1a91317f1aa1 alpha-oligomannoside dimannoside Manα1-3Man disaccharide 1B G29313LW; G07490EK; G51379UR SUGARBIND; PUBDICT_GLYCAN_MOTIF bGSL:c319a2ae-7105-48bf-9a73-a552798c2002 arm-fucosylated N-glycan N-Glycan core, arm-fucosylated; outer-arm-fucosylated N-glycan; antenna-fucosylated N-glycan; branch-fucosylated N-glycan 1B G05006NI GlycoMotif:GGM.001025 GLYCOMOTIF_GGM bGSL:484d3ba3-a21a-447a-9e16-863f9b99e935 biantennary LacdiNAc LacdiNAc-bearing biantennary N-glycan Bi-LDN 1B BIOOLIGO bGSL:edef038b-559f-4c0f-8123-33d8e93f6818 biantennary N-glycan diantennary asialylated biantennary N-glycan; biantennary complex-type N-glycan; core-fucosylated biantennary N-glycan; monosialylated biantennary N-glycan; nonfucosylated biantennary N-glycan; sialylated biantennary N-glycan; trisialylated biantennary N-glycan; disialylated biantennary N-glycan; tetrasialylated biantennary N-glycan 1B G98414DB GSD:00016 GlycoMotif:GGM.001037 GSD_GLYGEN_V1; EOG_VARKI_4E; GLYCOMOTIF_GGM Type of N-linked glycan in which two antenna are present on the trimannosyl core, each initiated by GlcNAc additions catalyzed by position-specific N-acetylglucosaminyltransferases (GlcNAcTs). Each antenna can be exteneded or capped with HexNAc, deoxyHex, Hex, or sialic acid residues. [Essentials of Glycobiology:Glossary] We found an efficient isopropylidenation reaction that selectively protects the terminal Gal-3,4-OH of a biantennary complex-type nonasaccharide isolated from a natural source.[PMID:29249147] bGSL:4adee05a-e4e2-4220-8012-96754acbc553 bisecting GlcNAc bisecting N-acetylglucosamine; bisecting β1-4GlcNAc; bisected bisecting α1-4GlcNAc 1B GSD:00156 GSD_GLYGEN_V1; EOG_VARKI_4E The bisecting GlcNAc is a modification of hybrid or complex N-linked glycans in which a single GlcNAc is added to the 3 position of the b-linked Man found in the trimannosyl core structure. The modification is catalyzed by beta 1,4-N-acetylglucosaminyltransferase III (GlcNAcT-III) or MGAT3 (E.C. 2.4.1.144). The addition of a bisecting GlcNAc on a hybrid or trimmed hybrid glycan prevents the subsequent action of N-glycan branching glycosyltransferases GlcNAcT-IV and GlcNAcT-V, but GlcNAcT3 can add a bisecting GlcNAc to the products of these enzymes. [PMID: 22476631] The presence of a bisecting GlcNAc and the occurrence of alpha 2-6-linked Neu5Ac in the most abundant N-glycans, are new features for hCG-beta.[PMID:1374031] bGSL:39b4fe22-c3e2-404b-a58e-488476c41ef2 bisecting α1-4GlcNAc bisecting GlcNAc 1B EOG_VARKI_4E A structural feature in certain fungal N-glycans where an N-acetylglucosamine (GlcNAc) is attached in an α1-4 linkage to the β-mannose core, distinct from the common β1-4-linked bisecting GlcNAc in mammals. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch23/#:~:text=This%20diversity%20would%20not%20have%20been,and%20host%E2%80%93pathogen%20interactions'] bGSL:8b567f45-d083-4326-9852-d0c5c67664ae branched N-glycan 1B EOG_VARKI_4E An N-linked glycan characterized by a branched structure, which can carry ABO(H) antigens and poly-LacNAc extensions. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch14/#:~:text=These%20variants%20are%20largely,branched%20N-glycan%20with%20poly-LacNAc'] bGSL:5e5390e4-6489-4ea0-aed0-eed678cc120f C-Series Gangliosides Oligosaccharide / Hemato- or Ganglio-Type ganglio-series glycosphingolipid C-Series Gangliosides Oligosaccharide / Gangliotetraosyl Core Structure 1B G45770AV GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCAN_IMAGE bGSL:250c2f66-a01e-477a-8ca3-3f79edb293ad C-Series Gangliosides Oligosaccharide / Gangliotetraosyl Core Structure C-Series Gangliosides Oligosaccharide / Hemato- or Ganglio-Type 1B G78818SP GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF bGSL:e2e26329-c55b-439a-b30f-db0496c2a6e8 ceramide dihexosyl sulfate dihexosylceramide sulfate; sulfated dihexosylceramide glycosylceramide Sulf-lactosylceramide 1B G04416BG; G50926NK; G98482BC GSD:00171 GlycoMotif:GGM.000065; GlycoMotif:CCRC.000065; GlycoMotif:GDV.000049 GSD_GLYGEN_V1; CUMMINGS; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF A sulfatide with two hexose moieties (glucose and galactose) has been isolated from human kidney (Martensson E, Acta Chem Scand 1963, 17, 1174). Equimolar amounts of ceramide, glucose, galactose, and sulfate are found in the molecule. The sulfate group is esterified, as in sulfatides, with carbon 3 of the galactose moiety. The linkage between galactose and glucose is identical to lactose (b-1-4). Its fatty acid composition is similar to that of sulfatides. [http://cyberlipid.gerli.com/description/complex-lipids/glycolipids/glycosphingolipids/sulfosphingolipids/] Although it has been reported that ceramide dihexosyl sulfate is present in human kidney, it is unlikely that it is present in equine kidney.[PMID:818074] bGSL:27b2c6f0-85f0-4646-9054-048231d54f58 Chondroitin tetrasaccharide chondroitin 1B BIOOLIGO bGSL:354dd5a3-9b0d-4dbd-82ce-94d6341c54fc complex-type N-glycan complex-type; complex N-glycan; complex N-linked glycan tetraantennary complex-type N-glycan; complex glycan biantennary complex-type N-glycan; sialylated complex-type N-glycan; highly branched complex-type N-glycan; multiantennary complex-type N-glycan 1B G35698AZ; G00030MO GSD:00032 GlycoMotif:GGM.001004 GSD_GLYGEN_V1; EOG_VARKI_4E; GLYCOMOTIF_GGM; PUBDICT_GLYCAN_MOTIF; PUBDICT_MOTIF_GTC Type of N-linked glycan in which at least two antenna are present on the trimannosyl core, each initiated by GlcNAc additions catalyzed by position-specific N-acetylglucosaminyltransferases (GlcNAcTs). Each antenna can be exteneded or capped with HexNAc, deoxyHex, Hex, or sialic acid residues. In this study, 32 new complex-type glycans are characterized containing the Le(x), Le(Y), and sialyl-Le(x) determinants, the bloodgroup A and H antigens, as well as the ALe(Y) determinant.[PMID:10988252] bGSL:e30de052-f784-47ff-a1be-0b40ce0773ac core-fucosylated glycan N-Glycan core, core-fucosylated; core-fucose; core-fucosylated N-glycan Core Fuc fucose core-fucosylated biantennary complex-type N-glycan; core-fucosylated biantennary N-glycan 1B G68504BA; G78059CC GSD:00037 GlycoMotif:GGM.001024 GLYCOMOTIF_GGM; GSD_GLYGEN_V1; EOG_VARKI_4E Modification of the N-glycan core structure with fucose moiety attached at the innermost GlcNAc by FUT8 enzyme. Core Fuc is found on paucimannose, hybrid and complex type N-glycans. [https://doi.org/10.1016/bs.acr.2014.11.006]. bGSL:2c82b80b-1a77-44ed-9bfe-660acf9a863c di-N-acetyllactosamine di-LacNAc; di-N-acetyllactosamine (type 2) Di-LN 1B PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV bGSL:bf65af89-774c-496f-a782-3e6c6e1db4d6 Disialyl-branched Type 2 disialylated biantennary complex-type N-glycan; disialylated biantennary N-glycan 1B G54937EM GlycoMotif:GDV.000107 CUMMINGS; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF bGSL:277b6391-bc41-42c6-8733-5a172a5adad4 disialylactose disialyllactose DiSai 1B G97569KL SUGARBIND; PUBDICT_GLYCAN_MOTIF bGSL:2bb283a3-6a83-4386-80e7-28412bdc6f2e Disialylated pentaose type 1 Disialosylpentaose 1B BIOOLIGO bGSL:a31b4be5-9bc0-4839-abe6-d36512f764ac Disialylated tetraose type 1 Sialylated tetraose type 1 1B BIOOLIGO bGSL:b467b8c4-5208-43c6-bae5-c62cbc79410f Disialylated tetraose type 2 Sialylated tetraose type 2; Sialylated tetraose type 1B BIOOLIGO bGSL:6bf908c1-decf-4709-9738-0382a1441412 fucosylated lacdiNAc LDNF fucosylated LDN; LDNF; LDN-F LacdiNAc Fuc a(1-3) Lac-di-Nac 1B G02240AO GSD:00055 GlycoMotif:GGM.000017; GlycoMotif:CCRC.000017; GlycoMotif:GDV.000067 GSD_GLYGEN_V1; CUMMINGS; GLYCOEPITOPE; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE An amino trisaccharide comprising an acetamido-β-D-galactose and an α-L-fucose attached to an acetamidoglucose by 1→4 and 1→3 linkages, respectively.[CHEBI:61864] To date, oligomeric LDN and oligomeric fucosylated LDN (LDNF) have been found only on N-glycans from mammalian cells engineered to express Caenorhabditis elegansbeta4-GalNAc transferase and human alpha3-fucosyltransferase IX [Z. S. Kawar et al. (2005) J Biol Chem280, 12810-12819]. [PMID:16403022] bGSL:ae1e37fa-f37f-4072-8e36-f0e3b32f8086 Gal a(1-3') LacNAc LacNAc-Gal 1B BIOOLIGO bGSL:2d28dd52-85bb-4d8e-a859-d8a2dd06d567 Galactosyl lactose a-3Galactosyl-3Fucosyllactose; a-4Galactosyl-3Fucosyllactose 1B BIOOLIGO bGSL:1d2b6e18-8da4-49b6-8335-c8bdbf7b3364 Galα1-3-type 1 chain alpha-galactosyl type 1 chain Gala3-type1 1B PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV bGSL:0f05da85-4561-457f-b205-a3946a29f1fd GlcNAc-LacNAc N-acetylglucosaminyl-N-acetyllactosamine GNLN 1B PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV bGSL:bc8a6ca3-0fc6-40c1-919f-0013f3971392 high-mannose N-glycan high-mannose type; oligomannose N-glycan; high mannose; high-mannose-type N-glycan; oligomannose-type N-glycan; oligomannosyl N-glycan mannose-terminated N-glycan; oligomannose monoglucosylated N-glycan 1B G55220VL; G00028MO GSD:00088 GlycoMotif:GGM.001002 GSD_GLYGEN_V1; EOG_VARKI_4E; GLYCOMOTIF_GGM; PUBDICT_GLYCAN_MOTIF; PUBDICT_MOTIF_GTC An N-linked oligosaccharide that possesses between five and nine mannose residues attached to the chitobiose [(GlcNAc)2] core. [CHEBI:5717] None of the Man residues are substituted with any monosaccharide other than Man . Each glycoform contained a number of peaks differing by 162 Da indicating heterogeneity and suggesting the presence of high-mannose sugars.[PMID:11258925] bGSL:17f2063f-8595-48ab-9d94-0f3d239ed053 hybrid N-glycan hybrid-type N-glycan; hybrid-type 1B G16828VN; G19610CW; G00029MO GSD:00090 GlycoMotif:GGM.001003 GSD_GLYGEN_V1; EOG_VARKI_4E; GLYCOMOTIF_GGM; PUBDICT_GLYCAN_MOTIF; PUBDICT_MOTIF_GTC An N-linked glycan in which the Manα1-6 arm of the trimannosyl core Manα1-3(Manα1-6)Manβ1-4GlcNAcβ1–4GlcNAcβ1–Asn-X-Ser/Thr is substituted by one or more additional Man residues and the Manα1-3 arm is substituted by a GlcNAc residue added by GlcNAcT1. The GlcNAc linked to the a3 Man can be extended in the same manner as any complex glycan antenna. The trimannosyl core can also be core fucosylated and/or bisected by the addition of a GlcNAc to the 3 position of the α-linked Man residue.[Essentials of Glycobiology:Chapter 9] A hybrid-type N-glycan was accessed by total synthesis, converted to an oxazoline, and used as a donor substrate with both wild type Endo M and an N175Q glycosynthase Endo M mutant allowing the convergent synthesis of a glycosylated amino acid bearing a hybrid N-glycan structure. [PMID:27058295] bGSL:59b08792-64a6-4133-8633-679cfa150669 LacdiNAc LDN LDN; LacdiNac fucosylated lacdiNAc; sialylated LacdiNAc; Fuc a(1-3) Lac-di-Nac; 4'-sulfated LDN 1B G31736BK; G00057MO GSD:00096 GlycoMotif:GGM.000016; GlycoMotif:CCRC.000016; GlycoMotif:GDV.000074 GSD_GLYGEN_V1; EOG_VARKI_4E; CUMMINGS; GLYCOEPITOPE; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; PUBDICT_MOTIF_GTC; PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV An amino disaccharide consisting of N-acetylglucosamine having an N-acetylgalactosaminyl resiude attached at the 4-position via a β-linkage.[CHEBI:61190] We previously showed that the expression level of the LacdiNAc group in N-glycans decreases dramatically during the progression of human breast cancer.[PMID:25003135] bGSL:5ad165db-a391-469e-840b-060f0ee60aab LacNAc-Gal Gal a(1-3') LacNAc 1B G06580KR GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:3ff774ff-a78d-4e5f-bf37-e5527b396a11 Lacto-N-Tetraose Lactotetraose LNT 1B G45827GY GLYCOEPITOPE; SUGARBIND; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV; BIOOLIGO bGSL:6af6ab8d-2be6-4ec4-9a67-b98617113056 lipid A core oligosaccharide LPS core 1B EOG_VARKI_4E The lipid A-core is a glycan-lipid structure in which lipid A is covalently linked to the core oligosaccharide region of lipopolysaccharide (LPS). This structure serves as a substrate for transport and further modification in Gram-negative bacteria. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch21/#:~:text=The%20formation%20of%20Kdo2%E2%80%93lipid%20A%20is,of%20two%20main%20synthetic%20strategies', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch21/#:~:text=The%20assembly%20of%20O-PS%20occurs,appropriate%20for%20their%20function%28s%29'] bGSL:88887b53-88e2-4c19-b72d-8c8059a5f821 LN3 i antigen Type 1 LN3; Mono-fucosyl LN3 1B G85779MY GlycoMotif:CCRC.000007 GLYCOMOTIF_CCRC; PUBDICT_GLYCAN_MOTIF; BIOOLIGO bGSL:5b0e6312-9bb4-435f-959b-0f35756e8fac LNFP II Mono-fucosyl LN3 1B G98173LG SUGARBIND bGSL:d0892201-68d8-44e7-8143-c017e8cddae9 LPS core lipid A core oligosaccharide 1B G00022MO PUBDICT_GLYCAN_MOTIF bGSL:025d5e83-acf9-4fd5-b300-c9a7532227e2 LS-hexasaccharide d Lewis y (Ley-6) 1B BIOOLIGO bGSL:3b1ea0dd-2cb8-4df4-b0e1-5df8ee45ead9 LS-tetrasaccharide d 1B BIOOLIGO bGSL:33131db8-3b39-4539-82f9-7f4d9281d101 Man-3 chitobiose core Fuc 1B BIOOLIGO bGSL:b59ee7eb-3696-4554-b077-db56798217cd Mono-fucosyl LN Mono-fucosyl LN3; Mono-fucosyl LN5 1B G64227KZ; G65223RT GlycoMotif:GDV.000041; GlycoMotif:GDV.000042 GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF bGSL:2d26546d-b73f-43c9-b515-92530e8578bd Mono-fucosyl LN3 Mono-fucosyl LN_3 LN3; Mono-fucosyl LN LNFP II 1B G65223RT; G80291PD GlycoMotif:GGM.000122; GlycoMotif:CCRC.000122 CUMMINGS; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; PUBDICT_GLYCAN_MOTIF bGSL:8cb73182-ac53-4d85-9438-10b8cbc80ebd Mono-fucosyl LN5 Mono-fucosyl LN_5 Mono-fucosyl LN 1B G64227KZ; G93536PN GlycoMotif:GGM.000121; GlycoMotif:CCRC.000121 CUMMINGS; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; PUBDICT_GLYCAN_MOTIF bGSL:4d79a8e1-87d9-5479-be29-5fbed42f9a0a N-acetyllactosamine Lactosamine; N-Acetyl-D-Lactosamine LacNAc; LN N-acetyllactosamine (type 1); N-acetyllactosamine (type 2) 1B G00055MO; G66213AR PUBDICT_MOTIF_GTC; PUBDICT_GLYCONAVI_NAME; EOG_VARKI_4E; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; PUBDICT_GLYCONAVI_ABBREV; BIOOLIGO LacNAc (N-acetyllactosamine, Galβ1-4GlcNAc) is a disaccharide motif commonly found in vertebrate N- and O-glycans, serving as a building block for more complex glycan structures such as Lewis antigens. bGSL:74815ce8-ad7a-446a-8973-d5b482079531 N-acetyllactosamine (type 1) N-acetyllactosamine type 1; Lactosamine Type 1; LacNAc type 1 Type 1 LN N-acetyllactosamine Type 1 LN2; Type 1 LN3 1B G00056MO; G43784HS GSD:00110 GlycoMotif:GGM.000005; GlycoMotif:GDV.000035 GSD_GLYGEN_V1; CUMMINGS; GLYCOMOTIF_GGM; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; PUBDICT_MOTIF_GTC The N-acetyllactosamine type 1 (LacNAc type 1, Galβ1,3GlcNAc) is a well-known precursor of several important blood group epitopes, such as Lewis A, Lewis B, or sialyl Lewis A [1], which are involved in many biological processes, e.g., fertilization [2] and pathogen adhesion [3]. [PMID:28796164] bGSL:793bd80c-299d-5f1e-9eab-8d823925dba3 N-acetyllactosamine (type 2) N-acetyllactosamine type 2; LacNAc type 2 Type 2 LN N-acetyllactosamine i antigen; Type 2 LN2; α2-3 sialyllactosamine; 3'-sialyl-LacNAc (type 2) 1B G00055MO GSD:00111 GlycoMotif:GGM.000001; GlycoMotif:CCRC.000001; GlycoMotif:CCRC.000005; GlycoMotif:GDV.000046 GSD_GLYGEN_V1; PUBDICT_GLYCAN_MOTIF; CUMMINGS; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV N-acetyllactosamine is a beta-D-galactopyranosyl-(1→4)-N-acetyl-D-glucosamine having beta-configuration at the reducing end anomeric centre. It is also known as galb1-4glcnacb or lacnac, belongs to the class of organic compounds known as acylaminosugars. These are organic compounds containing a sugar linked to a chain through N-acyl group. N-Acetyllactosamine is an extremely weak basic (essentially neutral) compound (based on its pKa). N-Acetyllactosamine exists in all living organisms, ranging from bacteria to humans.[CHEBI:16153,HMDB0001542] Utilising a fast and sensitive screening method based on imidazolium-tagged probes, we report unprecedented reversible activity of bacterial beta1,4-galactosyltransferases to catalyse the transgalactosylation from lactose to N-acetylglucosamine to form N-acetyllactosamine in the presence of UDP.[PMID:31165848] bGSL:1512089d-892e-4c40-ad9e-557f7b95508e N-glycan core, bisected bisected complex-type N-glycan 1B G68395LV GlycoMotif:GGM.001023 GLYCOMOTIF_GGM TRUE bGSL:4c32be34-7c2a-4ab7-9858-458254c2619d N-Glycan truncated motif. First GlcpNAC cut off 1B G00027MO PUBDICT_GLYCAN_MOTIF TRUE bGSL:c291c1cc-9538-453b-86c2-cdabdc39b621 oligomannose oligomannosyl structure high-mannose N-glycan 1B EOG_VARKI_4E Oligomannose refers to glycan structures containing multiple mannose residues, commonly found as part of N-glycans or other glycan classes. These structures are recognized by specific lectins and are involved in protein interactions. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch33/#:~:text=These%20MRH%20domains%20contain%20the,from%20Sneha%20Komath%20and%20Anne%20Imberty'] ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch18/#:~:text=In%20contrast%2C%20most%20protists%20employ,body%20with%20stress-tolerant%20spores'] bGSL:c7ab58d3-ee4a-4837-83a6-522653d14d8a Outer arm fucose terminal fucose; terminal α-linked fucose; fucose 1B EOG_VARKI_4E A disaccharide motif in which fucose is α1-3 linked to N-acetylglucosamine. This structure is commonly found on the outer branches of N-glycan chains and plays a role in glycan degradation pathways. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch44/#:~:text=Much%20of%20the%20protein%20is%20probably,in%20some%20species%20unexplained'] bGSL:ad9b425e-3e6a-49aa-bba7-dc47105eaafb paucimannose N-glycan paucimannose; paucimannosidic N-glycan mannose-terminated N-glycan 1B GSD:00125 GSD_GLYGEN_V1; EOG_VARKI_4E Any N-linked glycan derivative with composition Man1-4Fuc0-1 GlcNAc2, in which the chitobiose core (GlcNAc2) is intact. Found in relatively large amounts in invertebrates and plants, they are formed by removal of the non-reducing terminal GlcNAc (\added by GlcNAcT1) from GlcNAcMan3-5GlcNAc2 by a Golgi hexosaminidase and subsequent removal of Man residues by Golgi mannosidases. Pauscimannose glycans have also been detected in vertebrates.[CHEBI:144386] The galactosylation of core fucose (GalFuc epitope) in paucimannose and complex-type N-glycans is characteristic of protostome organisms, including flatworms (planarians).[PMID:29475940] bGSL:ea94f26b-7e56-4f18-aa8e-e4209af2066a Poly-KDN 1B G42911NE GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:fc3ad1a1-8e2e-4d63-a472-61db8a9e4a72 poly-lacto-N-biose 1B EOG_VARKI_4E A glycan motif composed of repeating lacto-N-biose units (Galβ1-3GlcNAcβ1-3)n, commonly found as side chains on certain glycosylphosphatidylinositol (GPI) anchors, especially in protozoan parasites. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch12/#:~:text=A%20small%20number%20of%20enzymes%20involved,%28COPII%29-coated%20transport%20vesicles'] bGSL:de914bf2-14e8-4c6e-9459-01890b3902ed poly-mannose polymannosyl N-glycan; polymannose 1B EOG_VARKI_4E A polymannose has a backbone composed of repeating α1-6 linked mannose residues, characteristic of yeast N-glycans and forming the core of large polymannosyl structures. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch56/#:~:text=Because%20genetic%20engineering%20in,suitable%20for%20further%20engineering'] bGSL:37a5d56e-ecde-4bb4-ba33-f32660a63b01 poly-N-acetylglucosamine poly-GlcNAc PNAG 1B EOG_VARKI_4E Poly-N-acetylglucosamine is a bacterial exopolysaccharide composed of β1-6 linked N-acetylglucosamine residues. It is widely distributed among both Gram-positive and Gram-negative bacteria and plays a significant role in biofilm formation and immune evasion. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch21/#:~:text=However%2C%20streptococcal%20CPS%20can,and%20-negative%20species', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch21/#:~:text=Some%2C%20such%20as%20bacterial%20cellulose,mimicry%20of%20host%20cell%20components', '0510e190-b92e-4b8b-b51f-0e1f4e5bbb21'] bGSL:e2afd99d-0bc8-4aae-b5d1-fbfe97a0707d poly-N-acetyllactosamine poly-LacNAc; poly-LN 1B G00058MO EOG_VARKI_4E; PUBDICT_GLYCAN_MOTIF; PUBDICT_MOTIF_GTC Poly-N-acetyllactosamine (poly-LN) refers to a linear or branched glycan motif composed of repeating disaccharide units of galactose β1-4 linked to N-acetylglucosamine β1-3, denoted as (Galβ1-4GlcNAcβ1-3)n. These chains are commonly found on N- and O-glycans as well as glycolipids, where they can be further modified with sialic acid and fucose. Poly-N-acetyllactosamine structures serve as scaffolds for terminal glycan modifications and are recognized by galectins. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch11/#:~:text=One%20of%20the%20selectins%2C%20E-selectin%2C,recognition%20to%20activate%20NKT%20cells'] ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch14/#:~:text=These%20variants%20are%20largely,branched%20N-glycan%20with%20poly-LacNAc', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch14/#:~:text=Both%20of%20these%20integral%20membrane,on%20Type-1%20units%20%28Figure%2014.4%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch14/#:~:text=These%20interactions%20occur%20through,respectively%20%28Figure%2014.3%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch14/#:~:text=Similarly%2C%20poly-LacNAc%20extensions,Gal%20engagement%20%28Chapter%2036%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch36/#:~:text=Although%20most%20galectins%20bind,two%20CRDs%20bind%20different%20glycans', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch36/#:~:text=The%20compactly%20arranged%20structure,structures%20%28Chapter%2014%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch44/#:~:text=They%20appear%20like%20vesicles%20within,internal%20or%20the%20limiting%20membrane'] bGSL:b745cfd3-db3d-4c85-9d42-8a970be6487a Poly-N-Acetylneuraminic Acid poly-Neu5Ac poly-sialic acid 1B G80631ZD GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:6851e817-f845-463d-aa79-18940b695d20 Poly-N-Glycolylneuraminic Acid poly-NeuGc poly-sialic acid 1B G95717TY GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:3903db61-e55b-42f7-a694-0d30ee25a57d poly-sialic acid polysialic acid polySia; PSA Poly-N-Acetylneuraminic Acid; Poly-N-Glycolylneuraminic Acid 1B G77612ZC GSD:00126 GlycoMotif:GGM.000252 GSD_GLYGEN_V1; EOG_VARKI_4E; CUMMINGS; GLYCOMOTIF_GGM Polysialic acid (polySia) is a linear homopolymer of sialic acid (N-acetylneuraminic acid, Neu5Ac) residues, typically linked via α2-8 or α2-9 glycosidic bonds. These chains are commonly found on glycoproteins such as neural cell adhesion molecules (NCAM) and play important roles in vertebrate brain development, neural cell migration, and immune modulation. Polysialic acid (PSA) is a carbohydrate composed of a linear polymer of α2,8-linked sialic acids, primarily attached to the Neural Cell Adhesion Molecule (NCAM). [PMID:36076963] bGSL:0532f927-458c-4b7d-b1a2-1dfa10ea9ae3 polyfucose branch 1B EOG_VARKI_4E Glycan motifs characterized by multiple fucose residues attached as branches, frequently observed in schistosome glycoconjugates and associated with antigenic determinants like Lewisx and LacdiNAc. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch43/#:~:text=Life%20cycle%20of%20Schistosoma%20species%2C,polyfucose%20branches%20%28Figure%2043.8%29'] bGSL:45ce6542-2212-4421-a699-34461ef66e41 polyglycosylceramide 1B EOG_VARKI_4E Polyglycosylceramides are a class of glycolipids, also known as macroglycolipids, characterized by long glycan chains—often containing poly-N-acetyllactosamine—attached to a ceramide lipid anchor. These molecules can carry blood group antigens such as A, B, and H. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch14/#:~:text=Both%20of%20these%20integral%20membrane,on%20Type-1%20units%20%28Figure%2014.4%29'] bGSL:55ee9165-3dfa-4e8e-adde-683c3e9a41ef sialoglycan Sia-containing glycan; sialic acid-containing glycan sialoglycan polymer; O-linked sialoglycan; O-GalNAc-linked sialoglycans; sialylated complex-type N-glycan; sialylated biantennary N-glycan 1B EOG_VARKI_4E Sialoglycans are glycans (oligosaccharides or polysaccharides) that contain one or more sialic acid residues, typically as terminal (outermost) sugars on structures such as N-glycans, O-glycans, glycosphingolipids, milk oligosaccharides, or glycosylphosphatidylinositol (GPI) anchors. These molecules play important roles in cell recognition, immune modulation, and interactions with pathogens. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch15/#:~:text=Scientists%20monitoring%20influenza,and%20the%20structurally%20related%20E', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch15/#:~:text=Human%20mutations%20in%20Sialin%20cause,are%20rapidly%20excreted%20in%20the%20urine', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch15/#:~:text=The%20N-acetyl%20group%20facilitates,proteins%20and%20direct%20Sia%20function', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch54/#:~:text=After%20peracetylation%2C%20treatment,synthesis%20is%20very%20promising', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch15/#:~:text=Alternately%2C%20the%20same,type%2C%20tissue%20type%2C%20and%20species', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch15/#:~:text=Hierarchical%20levels%20of%20sialome,%28the%20whole%20glycome%29%20%28Figure%2015.3%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch15/#:~:text=As%20with%20the%20glycome%2C%20each%20cell,of%20Sias%20on%20capsules%20and%20O-antigens', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch15/#:~:text=Sias%20are%20released%20from,autophagy%20or%20phagocytosis', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch15/#:~:text=In%20some%20bacteria%2C%20pathways%20for%20Sia,to%20some%20intact%20cell%20surfaces%29', '6213bcb2-ec34-4f4c-afa0-167508b00725', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch15/#:~:text=There%20are%20still%20some%20major,may%20perhaps%20deter%20animal%20ingestion', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch15/#:~:text=Because%20plants%20do%20not%20express,that%20mediate%20biological%20processes', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch15/#:~:text=Scientists%20monitoring%20influenza,and%20the%20structurally%20related%20E', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch15/#:~:text=falciparum%20can%20bind%20to%20erythrocyte,that%20have%20adapted%20to%20them', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch15/#:~:text=Sias%20are%20also%20involved%20in,of%20lymphocytes%20from%20blood%20to%20lymph', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch15/#:~:text=Increased%20sialylation%20may%20also,been%20claimed%20to%20have%20some%20value', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch15/#:~:text=Efforts%20to%20use%20sialoglycans,but%20also%20to%20assure%20FDA%20approval', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch35/#:~:text=Structural%20studies%20have%20shown%20that,on%20other%20cells%20%28trans%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch35/#:~:text=Although%20CD33rSiglecs%20can%20modulate,another%20self-glycan%2C%20hyaluronan', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch35/#:~:text=As%20with%20many%20other%20classes%20of,Pamela%20Stanley%20and%20Susan%20L.%20Bellis', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch42/#:~:text=Pigs%20are%20susceptible%20to%20both%20%CE%B12-3,and%20virtually%20all%20herpesviruses'] bGSL:65e50c99-0f3d-442b-bdcc-822b64394849 sialoglycan polymer sialoglycan 1B EOG_VARKI_4E Polymers composed of repeating sialoglycan units, which can interact with Siglec receptors and modulate immune cell functions such as apoptosis. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch35/#:~:text=It%20has%20also%20been%20shown%20that,such%20as%20interleukin-5%20%28IL-5%29'] bGSL:12267fec-3373-4cee-bc06-05e0777ccf0c sialoglycolipid ganglioside sialylated glycolipid 1B EOG_VARKI_4E Sialoglycolipids are glycolipids that contain one or more sialic acid residues. Examples include gangliosides, which are abundant in neural tissues and play important roles in cell recognition and signaling. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch15/#:~:text=As%20with%20the%20glycome%2C%20each%20cell,of%20Sias%20on%20capsules%20and%20O-antigens'] bGSL:430f425f-bec8-4855-95b9-b71d1934570d sialopentaosylceramide ganglioside; glycosylceramide; sialylated glycolipid disialosyl globopentaosylceramide; Sialyllactotetraosylceramide 1B G13224CR; G96400MT GSD:00128 GlycoMotif:GGM.000097; GlycoMotif:CCRC.000097; GlycoMotif:GDV.000070 GSD_GLYGEN_V1; CUMMINGS; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF A ganglioside in which the oligosaccharide portion is composed of a pentasaccharide containing one or more sialic acid residues.[CHEBI:36542] Sialylpentaosylceramide detected with anti-GM2 monoclonal antibody. Structural characterization and complementary expression with GM2 in gastric cancer and normal gastric mucosap[PMID: 2139874] bGSL:71393045-d3ef-489e-ad58-513d395d91ec Sialyl 6-Sulfo LacNAc 6-sulfo LacNAc; 6'-sialyl-N-acetyllactosamine α2-6-sialylated 6-sulfo-LacNAc 1B G99745QX GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; BIOOLIGO bGSL:8cf3a123-99ad-4b8d-b42d-77cc026168c9 Sialyl-3-lactose Alpha 2-3 sialyllactose 3'SL 1B G91237TK; G56516VH SUGARBIND; PUBDICT_GLYCAN_MOTIF bGSL:341c60e2-93cd-4eea-8e5e-6f005f41f221 sialylated LacdiNAc LacdiNAc 1B G55583HW GSD:00135 GlycoMotif:GGM.000050; GlycoMotif:CCRC.000050; GlycoMotif:GDV.000118 GSD_GLYGEN_V1; CUMMINGS; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF; BIOOLIGO The major non-reducing epitopes in the complex-type glycans are: Gal beta 1-4GlcNAc (lacNAc), GalNAc beta 1-4GlcNAc (lacdiNAc), NeuAc alpha 2-6Gal beta 1-4GlcNAc (sialylated lacNAc), NeuAc alpha 2-6Gal beta 1-4GlcNAc (sialylated lacdiNAc), Gal beta 1-4(Fuc alpha 1-3)GlcNAc (Lewisx), and GalNAc beta 1-4(Fuc alpha 1-3)GlcNAc (lacdiNAc analogue of Lewisx).[PMID:7592613] bGSL:70953dad-d43e-4a2d-9acb-3cb24d3b3444 sialylated N-acetyllactosamine 3'-sialyl-LacNAc (type 1) α2-6-sialylated 6-sulfo-LacNAc; α2-3 sialyllactosamine; 6'-sialyl-N-acetyllactosamine; 3'-sialyl-LacNAc (type 2) 1B EOG_VARKI_4E Sialylated N-acetyllactosamine refers to N-acetyllactosamine disaccharides that have a terminal sialic acid residue. These structures are found in bacterial capsules and serve as targets for certain antibodies. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch20/#:~:text=Interestingly%2C%20most%20such%20examples,with%20a%20structural%20resemblance', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch46/#:~:text=This%20antibody%20is,sialylated%20blood%20group%20antigen%20N'] bGSL:ce38c305-720a-4d65-937e-39df55a1c824 Sialylated tetraose type Sialylated tetraose type 1; Sialylated tetraose type 2; Disialylated tetraose type 2 1B BIOOLIGO bGSL:5c9789ea-fa40-414d-958a-1dfb0856a76b Sialylated tetraose type 1 Sialylated tetraose type Disialylated tetraose type 1 1B BIOOLIGO TRUE bGSL:fa064f14-31c9-40b8-8514-75039e24847d Sialylated tetraose type 2 Sialylated tetraose type Disialylated tetraose type 2 1B BIOOLIGO TRUE bGSL:b03ae050-187c-4876-b078-d96300fb819c Sialylated triose type 1 1B BIOOLIGO TRUE bGSL:88b4de04-0f9c-4775-b8af-257d8bff5f6c Sialyllacto-N-neotetraose Sai-LNnT 1B SUGARBIND bGSL:d99d1c89-aa54-436f-8b79-6ef9baf87928 Sialyllacto-N-tetraose b LSTb 1B G32417JV SUGARBIND; PUBDICT_GLYCAN_MOTIF; BIOOLIGO bGSL:5ecb0382-6560-4ec0-9d86-a132925e9859 Sulfated sialyl-3-N-acetyllactosamine Sulfated trisaccharide su-3'SLN α2-3 sialyllactosamine; 3'-sialyl-LacNAc (type 2) 1B G99745QX SUGARBIND; PUBDICT_GLYCAN_MOTIF bGSL:dee981c9-3ae5-4969-a995-b550ac3999f4 tetraantennary N-glycan sialylated tetraantennary N-glycan; fucosylated tetraantennary N-glycan; tetraantennary complex-type N-glycan 1B G33451SJ GSD:00144 GlycoMotif:GGM.001039 GSD_GLYGEN_V1; EOG_VARKI_4E; GLYCOMOTIF_GGM Type of N-linked glycan in which four antennae are present on the trimannosyl core, each initiated by GlcNAc additions catalyzed by position-specific N-acetylglucosaminyltransferases (GlcNAcTs). The four antennae are initiated by addition of 2 GlcNAcs to the _3 Man (at the 2 and 4 positions) and 2 GlcNAcs to the _6 Man (at the 2 and 6 positions) of the trimannosyl core. Each antenna can be extended or capped with HexNAc, deoxyHex, Hex, or sialic acid residues. [Essentials of Glycobiology:Glossary] In contrast, myeloma IgE showed a higher abundance of triantennary and tetraantennary glycan structures and a low abundance of species with a bisecting N-acetylglucosamine.[PMID:24308486] bGSL:bbbb4bc5-9c0a-47e4-b279-34d1c24e6afa tri-LacNAc Tri-LN 1B PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV bGSL:c25e4c88-2b14-43bc-9d78-84c9b9d90fab tri-mannose / O-linked tri-Man-Ser/Thr O-mannose glycan; Mannotriose; O-mannose glycan / yeast 1B EOG_VARKI_4E A glycan composed of three mannose residues, found as a modification on intracellular proteins in Saccharomyces cerevisiae. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch18/#:~:text=Paralogs%20of%20these%20enzymes%20have%20not,%28GTs%29%20that%20extend%20the%20first%20sugar'] bGSL:36e0f118-fbf4-494e-80f9-55c86020bd71 triantennary N-glycan tri-antennary N-glycan triantennary complex-type N-glycan; nonfucosylated triantennary N-glycan; fucosylated triantennary N-glycan; fucosylated trisialylated triantennary N-glycan; trisialylated triantennary N-glycan 1B G59096WE GSD:00148 GlycoMotif:GGM.001038 GSD_GLYGEN_V1; EOG_VARKI_4E; GLYCOMOTIF_GGM Type of N-linked glycan in which three antennae are present on the trimannosyl core, each initiated by GlcNAc additions catalyzed by position-specific N-acetylglucosaminyltransferases (GlcNAcTs). The three antennae can be be initiated by addition of 2 GlcNAcs to the _3 Man (at the 2 and 4 positions) and 1 GlcNAc to the _6 Man (at the 2 position) of the trimannosyl core or 1 on the _3 and 2 on the _6 Man (at the 2 and 6 positions). Each antenna can be extended or capped with HexNAc, deoxyHex, Hex, or sialic acid residues. [Essentials of Glycobiology:Glossary] Increased expression of the high-mannose M6N2 and NeuAc3H3N3M3N2F tri-antennary N-glycans in cholangiocarcinoma.[PMID:29399163] bGSL:a552afb6-e3d1-4f95-94d9-d78a69dc0219 trimannosyl core N-linked glycan core; 3a,6a-mannopentaose truncated N-glycan Man3 1B G20624LQ; G00026MO; G63560NE; G59883YF GSD:00152 GlycoMotif:GGM.001001; GlycoMotif:GGM.001022; GlycoMotif:GGM.001041 GSD_GLYGEN_V1; EOG_VARKI_4E; SUGARBIND; GLYCOMOTIF_GGM; PUBDICT_GLYCAN_MOTIF; PUBDICT_MOTIF_GTC A glycan that constitutes the core structure common to all high-mannose, complex, or hybrid N-glycans. The trimannosyl core composition is Man3 GlcNAc2 and includes a chitobiose at the reducing terminal which is extended by a single b-linked Man residue. The b-linked Man is branched by two additional a-linked Man residues, one at the 3 position and one at the 6 position. This glycoengineered H. polymorpha strain produced glycoproteins mainly containing trimannosyl core N-glycan (Man(3)GlcNAc(2)), which is the common core backbone of various human-type N-glycans.[PMID:18320567] bGSL:2a02e54d-20b1-40ec-beae-e197ec9fb72e Trisialylated pentaose type 1 1B BIOOLIGO TRUE bGSL:4eb5f9af-111d-48ff-9eea-37d3d1837307 Trisialylated pentaose type 2 1B BIOOLIGO TRUE bGSL:2429ce2a-67b7-414b-bd18-e6138fa0fa8d Type 1 LN2 N-acetyllactosamine (type 1) 1B G43784HS GlycoMotif:GGM.000006 CUMMINGS; GLYCOMOTIF_GGM; PUBDICT_GLYCAN_MOTIF TRUE bGSL:e6dcb0cd-2fbc-496c-823d-21e64934f8c8 Type 1 LN3 N-acetyllactosamine (type 1); LN3 1B G17961XM GlycoMotif:GGM.000007; GlycoMotif:GDV.000034 CUMMINGS; GLYCOMOTIF_GGM; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF TRUE bGSL:117ad347-48da-52fd-8e65-41bdc36df900 Type 2 LN2 i antigen; N-acetyllactosamine (type 2) 1B G00058MO; G45207BM GlycoMotif:GGM.000002; GlycoMotif:CCRC.000002; GlycoMotif:CCRC.000006; GlycoMotif:GDV.000045 CUMMINGS; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF TRUE bGSL:fba1a167-35e6-4647-b016-9ccd74d706b7 α2-6-sialylated 6-sulfo-LacNAc 6-sialyl-6-sulfo LN 6-sulfo LacNAc; sialylated N-acetyllactosamine; Sialyl 6-Sulfo LacNAc; 6'-sialyl-N-acetyllactosamine 1B G41145LF; G43191LZ; G92341SR GSD:00001 GlycoMotif:GGM.000026; GlycoMotif:CCRC.000026; GlycoMotif:GDV.000115 GSD_GLYGEN_V1; CUMMINGS; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF The alpha2-6-sialylated 6-sulfo-LacNAc determinant defined by the antibody was significantly expressed on a majority of normal human peripheral B-lymphocytes as well as follicular B-lymphocytes in peripheral lymph nodes.[PMID:17728258] bGSL:5d39de6c-5571-4f87-a2f9-3b3feb4da7c6 1-3,1-4 beta Glucan 1C G46558JB GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:50a8fe3f-2dd4-43c0-a999-04697b3e76de 1-6 beta Galactan 1C G69386QK GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:2a5b0fb1-4149-4f06-9ab9-f1c0678b0296 amylopectin glucan 1C EOG_VARKI_4E Amylopectin is a branched polysaccharide consisting of α-1,4-linked D-glucose units with α-1,6-linked branch points. It is one of the two major components of starch. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch24/#:~:text=Amylopectin%20is%20a%20branched%20polymer,walls%20that%20surround%20plant%20cells'] bGSL:2ad16e8c-7414-4587-b682-1194e1ed03dd amylose α-linked polyglucose 1C G05740LL PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; PUBDICT_GLYCONAVI_NAME bGSL:6151b40c-46b1-4b60-8ee0-2c527e8b2dcd apiogalacturonan 1C EOG_VARKI_4E Apiogalacturonan is a class of plant cell wall pectic polysaccharides characterized by a galacturonic acid backbone with β-D-apiose (Apif) and apiobiose residues attached to the O-2 position of some backbone residues. These polysaccharides are found in duckweeds and seagrasses. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch24/#:~:text=Apiogalacturonans%20have%20only%20been,each%20RG-II%20monomer%20%28Figure%2024.2%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch24/#:~:text=Rhamnogalacturonan-I%20%28RG-I%29%20is%20a,of%20some%20of%20the%20backbone%20residues'] bGSL:6e9079b8-7681-42a4-9918-09504cee1cc6 Arabinan 1C G22535ZZ GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:959c876e-81fd-42b2-9e6a-1508246969fe Arabinogalactan Type I 1C G98272RS GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:df06ac3f-72ee-43a9-b405-47271abb611d Arabinogalactan Type II 1C G12828SG GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:4e4f1007-0c77-4eee-a493-1d194d348ae4 arabinoglucuronoxylan glucuronoxylan 1C G54315VV EOG_VARKI_4E; GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE Arabinoglucuronoxylan (AGX) is a type of plant cell wall hemicellulose found in gymnosperms, characterized by a xylan backbone that is substituted with both methylglucuronic acid (MeGlcpA) and arabinofuranose (Araf) residues. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch24/#:~:text=Glucuronoxylans%2C%20which%20are%20major,their%20reducing%20end%20%28Figure%2024.1C%29'] bGSL:331ae9a8-5be1-494b-9967-0a34b58d0287 beta 1-4 Galactan galactan 1C G77076MY GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:2e25df07-7bb9-435d-8de8-1ce20e94b6ce callose 1C EOG_VARKI_4E Callose is a plant and fungal polysaccharide composed primarily of β-1,3-linked glucose residues, sometimes featuring β-1,6 branches. It plays important roles in cell wall structure and is involved in defense responses. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch24/#:~:text=Plant%20proteoglycans%20are,of%20N-glycans%20identified%20in%20plants', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch40/#:~:text=More%20recently%2C%20additional%20plant,fungal%20and%20oomycete%20cell%20walls', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch40/#:~:text=For%20example%2C%20%CE%B2-1%2C3-glucan,respectively%20%28Figure%2040.2%29'] bGSL:3eda4500-2c86-42dc-b89c-62af4f66d8c5 cellulose 1C G00025MO EOG_VARKI_4E; PUBDICT_MOTIF_GTC Cellulose is a linear polysaccharide made up of β-1,4-linked glucose units. It serves as the primary structural component of plant cell walls and is one of the most abundant biopolymers found in nature. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch04/#:~:text=In%20addition%2C%20select%20cytosolic,space%2C%20as%20described%20below', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch08/#:~:text=Free-living%20fungi%20and%20the,the%20action%20of%20dozens%20of%20GTs', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch16/#:~:text=However%2C%20this%20is%20not%20the%20case%2C,of%20%E2%88%BC10%20%C2%B5m%20%28%E2%88%BC1%20nm/disaccharide%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch20/#:~:text=An%20independent%20clade%20of%20enzymes,chitin%2C%20and%20glycosaminoglycans', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch40/#:~:text=For%20example%2C%20%CE%B2-1%2C3-glucan,respectively%20%28Figure%2040.2%29'] bGSL:222e0a6c-cbcc-40c4-92db-a6f0093b1a4f chitin 1C G97099AY EOG_VARKI_4E; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE Chitin is a linear polymer composed of β-D-N-acetylglucosamine (GlcNAc) residues linked via β(1→4) glycosidic bonds. It forms the structural backbone of invertebrate exoskeletons and fungal cell walls, providing strength and rigidity. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch59/#:~:text=These%20products%20are%20used%20in%20many,waste%20into%20value-added%20products'] ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch04/#:~:text=In%20addition%2C%20select%20cytosolic,space%2C%20as%20described%20below', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch16/#:~:text=However%2C%20this%20is%20not%20the%20case%2C,of%20%E2%88%BC10%20%C2%B5m%20%28%E2%88%BC1%20nm/disaccharide%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch20/#:~:text=An%20independent%20clade%20of%20enzymes,chitin%2C%20and%20glycosaminoglycans', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch23/#:~:text=The%20extracellular%20matrix%20of%20all,glucose%2C%20just%20like%20intact%20cells'] bGSL:d4536f64-d3b3-4643-93d0-0259dfaa3324 cyclic β1-2 glucan glucan; β-glucan 1C EOG_VARKI_4E Cyclic β1-2 glucans are polysaccharides consisting of 17–25 glucose units connected by β1-2 linkages. They are synthesized by certain bacteria, such as Agrobacterium. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch21/#:~:text=However%2C%20because%20not%20all,to%20the%20neutral%20species.%20In%20E'] bGSL:b2313688-c561-47d1-8b10-a52f877dfebf dextran 1C EOG_VARKI_4E Dextran is a class of polysaccharides composed primarily of α(1→6)-linked D-glucose units with occasional α(1→3) branches, and is commonly produced by certain bacteria. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch34/#:~:text=A%20number%20of%20proteins%20with%20CTLDs,are%20preceded%20by%20a%20signal%20sequence'] bGSL:6c107b0b-52a7-4a86-8412-9ed3628abf92 fructan 1C EOG_VARKI_4E Fructans are storage polysaccharides made primarily of fructose units. They are commonly found in green plants, where they are stored in vacuoles and serve as energy reserves. Fructans may also contribute to plant protection against abiotic stress. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch24/#:~:text=Amylopectin%20is%20a%20branched%20polymer,walls%20that%20surround%20plant%20cells', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch59/#:~:text=The%20chemical%20energy%20generated%20in,materials%20in%20the%20United%20States'] bGSL:43856398-2030-4e92-ae15-880c6aa91bc7 fucoidan 1C EOG_VARKI_4E Fucoidans are sulfated polysaccharides mainly composed of fucose residues, typically featuring alternating 1-3 and 1-4 linkages. They are isolated from brown algae and are recognized for their diverse biological activities. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch24/#:~:text=Laminaran%20is%20a%20linear%20storage,and%20the%20chloroplast%20membrane'] bGSL:6860b937-40c2-404f-a59d-007aaea661e6 galactan sulfated galactan; beta 1-4 Galactan 1C EOG_VARKI_4E A polysaccharide composed primarily of galactose residues, commonly found in fungal and plant cell walls. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch23/#:~:text=The%20extracellular%20matrix%20of%20all,glucose%2C%20just%20like%20intact%20cells'] bGSL:f31f7bb1-a02f-4193-9292-f65a9441889a galactomannan 1C G93424OB EOG_VARKI_4E; GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE A polysaccharide composed of a mannose backbone with galactose side chains, commonly found in plant and fungal cell walls. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch08/#:~:text=Free-living%20fungi%20and%20the,the%20action%20of%20dozens%20of%20GTs', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch23/#:~:text=This%20foundational%20work%20in%20cell,between%20different%20fungal%20species'] bGSL:e713edcf-8dea-4107-8cba-d3a2ee40e3de gellan 1C G41181BF PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:2d7ec4da-de37-4369-80ea-73d5da660cb2 glucan glucose polymers cyclic β1-2 glucan; amylopectin; β-glucan 1C EOG_VARKI_4E Glucans are polysaccharides composed of glucose monomers linked by glycosidic bonds. They include various linkage types (such as β1-3, β1-4, β1-6, α1-3, and α1-4) and form the structural basis of cellulose and other fungal and plant cell wall components. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch24/#:~:text=Several%20of%20these%20chains%20are,to%20the%20axis%20of%20elongation', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch59/#:~:text=Nanomaterials%20from%20plants%20and,arrangements%20%28see%20Figure%2059.1A%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch24/#:~:text=The%20newly%20formed%20microfibrils%20are,and%20%CE%B2-glucosidases', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch24/#:~:text=Most%20pectins%20and%20hemicellulose%20are,low%20abundance%20in%20the%20wall', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch59/#:~:text=During%20cellulose%20biosynthesis,cellulose%20chains%20%28CNs%3B%20Chapter%2058%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch23/#:~:text=The%20extracellular%20matrix%20of%20all,glucose%2C%20just%20like%20intact%20cells', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch23/#:~:text=This%20foundational%20work%20in%20cell,between%20different%20fungal%20species', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch23/#:~:text=Illustration%20of%20the%20cell%20wall%20of,and%20%CE%B11-4%2C%20also%20occur%20in%20fungi', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch40/#:~:text=In%20more%20advanced%20eukaryotes%2C%20this,fragments%20as%20DAMPs%20%28Figure%2016.6%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch18/#:~:text=Glycogenin-like%20proteins%20are%20found,localized%20mannogen%20synthase'] bGSL:57849b90-baf4-4731-ad47-cad2dcd41396 glucomannan 1C G88924MD EOG_VARKI_4E; GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE A hemicellulosic polysaccharide composed of glucose and mannose residues, commonly found in fungal cell walls and plant tissues. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch23/#:~:text=This%20foundational%20work%20in%20cell,between%20different%20fungal%20species'] bGSL:2188a9f4-31f0-44fa-a733-e732d88266b3 glucuronoxylan arabinoglucuronoxylan 1C G94091AV EOG_VARKI_4E; GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE Glucuronoxylan is a hemicellulosic polysaccharide characterized by a xylan backbone substituted with α-D-glucuronic acid or methylated glucuronic acid at the O-2 position. It is a major component of secondary cell walls in woody and herbaceous eudicots as well as higher plants. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch24/#:~:text=The%20latter%20scenario%20is%20analogous,substituent%20at%20O-2%20%28Figure%2024.1C%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch08/#:~:text=Free-living%20fungi%20and%20the,the%20action%20of%20dozens%20of%20GTs'] bGSL:32af4552-8334-4c12-bd1b-d904c6b89b0d glycogen 1C EOG_VARKI_4E Glycogen is a highly branched glucose polymer composed mainly of α(1-4)-linked glucose residues with α(1-6)-linked branch points. It serves as a major glucose storage polysaccharide in animals, allowing for rapid mobilization of glucose when needed. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch03/#:~:text=Other%20important%20polysaccharides%2C,to%20some%20of%20the%20glucose%20residues', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch18/#:~:text=This%20may%20differentially%20regulates,at%20Tyr-195%20in%20human%20glycogenin-1'] bGSL:4400daf1-ffb0-428a-a3a5-9580c063e24c hemicellulose Hemicellulosic polysaccharides 1C EOG_VARKI_4E Hemicellulose refers to a class of branched plant cell wall polysaccharides characterized by a backbone of 1-4-linked β-D-pyranosyl residues, such as glucose, mannose, or xylose. This group includes xylans, glucuronoxylans, galactomannans, and xyloglucans. Hemicelluloses are synthesized in the Golgi apparatus and secreted into the apoplast, where they contribute to the structure and function of plant cell walls. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch20/#:~:text=An%20independent%20clade%20of%20enzymes,chitin%2C%20and%20glycosaminoglycans', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch20/#:~:text=The%20most%20abundant%20biopolymers%20in,forces%20driving%20their%20evolution', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch24/#:~:text=This%20involves%20several%20types%20of,definition%20of%20hemicelluloses', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch24/#:~:text=Xyloglucan%2C,and%20O-acetyl%20substituents', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch08/#:~:text=Free-living%20fungi%20and%20the,the%20action%20of%20dozens%20of%20GTs', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch59/#:~:text=Chitosan%20has%20reactive%20amino%20and,their%20material%20properties'] bGSL:1d53d397-8d2c-4fc5-ae72-df2d907b8801 heteroxylan xylan 1C EOG_VARKI_4E Heteroxylan refers to a class of hemicellulosic polysaccharides found in the secondary cell walls of seed-producing plants. These polysaccharides are characterized by a β-1,4-linked D-xylopyranose backbone with various substituents, and are classified based on the type and abundance of these substituents. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch24/#:~:text=The%20latter%20scenario%20is%20analogous,substituent%20at%20O-2%20%28Figure%2024.1C%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch24/#:~:text=Eudicot%20and%20gymnosperm%20secondary,polysaccharides%20are%20synthesized'] bGSL:35836fc1-c16c-402a-ba5e-145272c5dc57 homogalacturonan 1C G25318VQ EOG_VARKI_4E; GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE Homogalacturonan is a linear homopolysaccharide consisting of 1,4-linked α-D-galacturonic acid residues. It forms a major structural domain of pectin in plant cell walls, contributing to their integrity and function. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch24/#:~:text=Virtually%20all%20of%20the%20RG-II%20exists,fragmentation%20by%20microbial%20enzymes', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch24/#:~:text=RG-II%20was%20believed%20to%20be%20largely,of%20each%20pectin%20structural%20domain', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch24/#:~:text=The%20homogalacturonan%20region%20has%20a,or%20prevent%20interchain%20pairing', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch24/#:~:text=For%20example%2C%20the%20structural,temporal%20changes%20in%20the%20plant', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch40/#:~:text=Plant%20defense%20responses%20upon,proteins%20%28PGIP%29%20produced%20by%20plants', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch48/#:~:text=The%20higher%20valency%20of%20IgM,glycan%20or%20nonglycan%20substituents'] bGSL:b918a73e-e533-45a7-85ac-a27b4c720246 Inulin 1C PUBDICT_GLYCONAVI_NAME bGSL:a090cc96-b87b-4101-9f6d-c314e31a05ce levan-type fructan 1C EOG_VARKI_4E A fructan polysaccharide composed of linear β2-6-linked D-fructofuranose units, commonly found in grasses. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch24/#:~:text=Amylopectin%20is%20a%20branched%20polymer,walls%20that%20surround%20plant%20cells'] bGSL:b3b8c014-a291-48b8-99ef-c97688ebd327 lipo-chitooligosaccharide lipochitooligosaccharide LCO 1C EOG_VARKI_4E Lipo-chitooligosaccharides (LCOs) are a class of glycolipids consisting of a chitin-derived oligosaccharide backbone linked to a fatty acid. They are produced by bacterial and fungal symbionts and are recognized by plant receptors, triggering various biological responses. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch07/#:~:text=However%2C%20even%20the%20most%20precise,and%20structure-dependent%20manner'] bGSL:64f85be6-bb16-4905-8a36-65b8ae88444f lipopeptidophosphoglycan LPPG 1C EOG_VARKI_4E A complex glycoconjugate composed of lipid, peptide, and phosphoglycan components, as exemplified by the lipopeptidophosphoglycan (LPPG) found in Entamoeba histolytica. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch43/#:~:text=Leishmania%20LPG%20and%20LPPG%20are,inflammatory%20responses'] bGSL:5d0bcc5a-b76e-4ccb-b748-6a8abb9afd0a lipoteichoic acid LTA teichoic acid 1C EOG_VARKI_4E Lipoteichoic acids (LTAs) are anionic glycopolymers present in the cell envelopes of Gram-positive bacteria. They typically consist of polyglycerol phosphate chains anchored to a glycolipid, and display diverse carbohydrate structures. Their biosynthetic pathways are distinct from those of wall teichoic acids. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch21/#:~:text=WTAs%20also%20provide%20a%20means%20of,in%20Gram-positive%20cell%20envelopes', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch21/#:~:text=The%20timing%20%28during%20peptidoglycan,that%20do%20not%20contain%20teichoic%20acids', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch21/#:~:text=LTAs%20may%20coexist%20with%20WTAs%2C%20and,resistance%20to%20many%20antibiotics', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch34/#:~:text=MBL%2C%20conglutinin%2C%20CL-43%2C%20CL-46%2C,is%20further%20augmented%20by%20SP-A'] bGSL:3a91788e-1281-48f8-92a3-6c77839119cd mannan 1C EOG_VARKI_4E Mannans are polysaccharides composed mainly of mannose residues, typically linked by β-1,4-glycosidic bonds. They are found in plant cell walls, as well as in the cell walls of fungi, yeast, and some bacteria, where they can serve structural or signaling functions. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch59/#:~:text=Current%20research%20is%20focused%20on,125%20years%20%28the%20viscose%20process%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch48/#:~:text=For%20example%2C%20the%20gene%20encoding%20a,glycans%20on%20their%20surface'] ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch05/#:~:text=In%20%E2%80%9Clower%E2%80%9D%20eukaryotes%20and,in%20eukaryotic%20cells%20%28Chapter%209%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch14/#:~:text=Phosphorylation%20of%20sugars%20is%20also,for%20HS%2C%20CS%2C%20or%20DS%20addition', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch23/#:~:text=The%20extracellular%20matrix%20of%20all,glucose%2C%20just%20like%20intact%20cells', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch23/#:~:text=This%20foundational%20work%20in%20cell,between%20different%20fungal%20species', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch23/#:~:text=yeast%29%20and%20function.%20Structures%20of,processing%20at%20Man9GlcNAc2Asn-R', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch23/#:~:text=P.%20pastoris%20has%20emerged%20as%20a,structure%20called%20the%20basidium', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch23/#:~:text=To%20convey%20the%20enormous%20diversity,plants%20and%20algae%20than%20in%20fungi.%20D', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch40/#:~:text=More%20recently%2C%20additional%20plant,fungal%20and%20oomycete%20cell%20walls', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch40/#:~:text=In%20more%20advanced%20eukaryotes%2C%20this,fragments%20as%20DAMPs%20%28Figure%2016.6%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch48/#:~:text=Mention%20should%20also%20be%20made%20about,capture%20of%20the%20tag%20%28e.g.%2C%20His%20tag%29'] bGSL:48ff3241-2b7d-423d-a21c-e26d12d8ba23 mannosylated lipoarabinomannan ManLAM 1C EOG_VARKI_4E Mannosylated lipoarabinomannan (ManLAM) is a form of lipoarabinomannan (LAM) found in mycobacteria, characterized by mannose residues capping its structure. As a glycolipid, ManLAM plays a key role in modulating immune responses by interacting with C-type lectin receptors. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch34/#:~:text=DCs%20also%20contribute%20to%20the%20balance,and%20limitation%20of%20DC%20maturation'] bGSL:4a6869c0-ea3c-4b4a-b4f5-8b9f6286c7a0 matriglycan 1C EOG_VARKI_4E Matriglycan is a specialized repeating disaccharide glycan synthesized on α-dystroglycan. It serves as a binding site for extracellular matrix proteins and certain viral proteins, and is an extended O-mannosyl glycan essential for the connection between muscle and the extracellular matrix. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch13/#:~:text=This%20action%20serves%20to%20prime%20the,have%20disaccharide-modified%20Hyl', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch20/#:~:text=O-Mannosylation%20plays%20diverse,serine%20and%20threonine%20%28Chapter%2024%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch56/#:~:text=Large%20libraries%20of%20isogenic%20cells,and%20TALEN-mediated%20gene%20knockout'] bGSL:ec47c367-2c76-4128-a384-ffafaecd8e49 methanochondroitin 1C EOG_VARKI_4E Methanochondroitin is a rigid fibrillar polysaccharide similar to chondroitin, composed of repeating units of one uronic acid and two N-acetylgalactosamine (GalNAc) residues, and is found as a cell surface polymer. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch22/#:~:text=Individual%20cells%20of%20Methanosarcina,of%20glucose%20and%20galactose%20acids'] bGSL:944e2364-bff4-4c70-a57c-2f3442fa6509 pectin 1C EOG_VARKI_4E Pectin is a structurally complex class of plant cell wall polysaccharides that are rich in 1-4-linked α-D-galacturonic acid (GalpA). It is primarily found in the primary cell walls of dicots, gymnosperms, and nongraminaceous monocots. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch24/#:~:text=They%20also%20contain%20structural,between%2018%20and%2024%20glucan%20chains', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch03/#:~:text=Figure%203.2%20depicts%20these,most%20complex%20polymers%20in%20nature', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch03/#:~:text=Other%20important%20polysaccharides%2C,to%20some%20of%20the%20glucose%20residues'] bGSL:cafaa941-774a-4e24-8f7d-3f76140967cd Peptidoglycan 1C G00023MO PUBDICT_GLYCAN_MOTIF; PUBDICT_MOTIF_GTC bGSL:56779267-08f6-4e26-a219-4612ce123627 phosphomannan 1C EOG_VARKI_4E Phosphomannan refers to polysaccharides composed of mannose residues with phosphate groups, commonly found in fungal cell walls. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch23/#:~:text=This%20foundational%20work%20in%20cell,between%20different%20fungal%20species'] bGSL:851535ce-1375-4960-a5a9-bdcb108c62ee phosphopeptidomannan 1C EOG_VARKI_4E Phosphopeptidomannan refers to immunogenic mannans that contain both phosphate and peptide groups, typically found in yeast cell walls. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch23/#:~:text=These%20organisms%20display%20diverse,of%20myo-inositol%20phosphate'] bGSL:7551b088-bee1-4e4e-a63d-e99ed3d4f8a9 pseudomurein pseudopeptidoglycan 1C EOG_VARKI_4E Pseudomurein is a glycan-based polymer present in the cell walls of certain methanogenic Archaea. It consists of glycan strands cross-linked by peptides composed of L-amino acids, and is structurally distinct from the peptidoglycan found in bacterial cell walls. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch22/#:~:text=Today%2C%20it%20is%20clear%20that%20protein,composition%20of%20the%20cell%20surface', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch22/#:~:text=Pseudomurein%20shares%20structural,chemical%20structure%20of%20pseudomurein'] bGSL:c7452fec-db7e-4db5-9825-a582482d26f2 raffinose 1C EOG_VARKI_4E; PUBDICT_GLYCONAVI_NAME Raffinose is part of a class of plant oligosaccharides, including stachyose and verbascose, which are water-soluble carbohydrates commonly found throughout the plant kingdom. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch24/#:~:text=Sucrose%20is%20the%20dominant%20transport,composed%20of%20only%20%CE%B1-1-4-linked%20Glcp'] bGSL:c0e9b2fa-1bae-4c6f-8062-c2b44dd03dd2 rhamnogalacturonan Rhamnogalacturonan-I; Rhamnogalacturonan-II 1C EOG_VARKI_4E Rhamnogalacturonan is a class of pectic polysaccharides found in plant cell walls, characterized by a backbone composed of rhamnose and galacturonic acid residues, and often featuring diverse oligosaccharide side chains. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch24/#:~:text=RG-II%20was%20believed%20to%20be%20largely,of%20each%20pectin%20structural%20domain', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch24/#:~:text=For%20example%2C%20the%20structural,temporal%20changes%20in%20the%20plant', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch24/#:~:text=The%20homogalacturonan%20region%20has%20a,or%20prevent%20interchain%20pairing', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch40/#:~:text=Many%20of%20these%20effects%20may%20result,involved%20in%20plant%20defense'] bGSL:e6892dfe-69d2-47ea-98f0-f55eb87758a5 Rhamnogalacturonan-I RG-I rhamnogalacturonan 1C EOG_VARKI_4E Rhamnogalacturonan I (RG-I) is a pectic polysaccharide characterized by a backbone of repeating disaccharide units composed of 4-α-D-galacturonic acid (GalpA) and 2-α-L-rhamnose (Rhap). It is a structural domain of pectin and can contain various side chains, such as arabinogalactan. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch24/#:~:text=The%20expression%20of%20genes%20involved,function%20remains%20to%20be%20determined', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch24/#:~:text=The%20carboxyl%20group%20may%20be,are%20acetylated%20at%20O-2%20and/or%20O-3'] bGSL:79619d66-44da-47f3-8d3d-479eca6bde4f Rhamnogalacturonan-II RG-II rhamnogalacturonan 1C EOG_VARKI_4E Rhamnogalacturonan II (RG-II) is a complex pectic polysaccharide domain present in plant cell walls, typically existing as a dimer cross-linked by a borate ester. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch24/#:~:text=Plant%20proteoglycans%20are,of%20N-glycans%20identified%20in%20plants', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch24/#:~:text=Virtually%20all%20of%20the%20RG-II%20exists,fragmentation%20by%20microbial%20enzymes'] bGSL:7960b548-5913-415f-bc36-8953c6662acd rhamnomannan 1C EOG_VARKI_4E Rhamnomannan is a complex polysaccharide found in fungal cell walls, composed of rhamnose and mannose residues. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch23/#:~:text=This%20foundational%20work%20in%20cell,between%20different%20fungal%20species'] bGSL:99666485-e50c-4f12-8d66-c20aaa6b8b07 starch 1C EOG_VARKI_4E Starch is a storage polysaccharide in plants composed of glucose units, typically arranged in insoluble, semicrystalline granules found within chloroplasts or amyloplasts. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch18/#:~:text=Interestingly%2C%20a%20novel%20Glc-Arg,of%20chloroplasts%20of%20certain%20algae', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch59/#:~:text=The%20chemical%20energy%20generated%20in,materials%20in%20the%20United%20States', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch24/#:~:text=Amylopectin%20is%20a%20branched%20polymer,walls%20that%20surround%20plant%20cells'] bGSL:e0f3e4b1-bd47-4eb5-8a21-e173206e09a6 sulfated galactan galactan; sulfated glycan 1C EOG_VARKI_4E A class of sulfated polysaccharides composed mainly of galactose residues, such as agarose and carrageenan, commonly found in red seaweeds. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch24/#:~:text=Such%20data%20are%20required%20to%20develop,unit'] bGSL:977b5e3e-cf1d-4504-8279-7cc26e14df47 teichoic acid teichoic acid polymer lipoteichoic acid 1C EOG_VARKI_4E Teichoic acids are polymers composed of repeating glycerol or ribitol phosphate units joined by phosphodiester linkages, and are found in the cell wall of Gram-positive bacteria. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch03/#:~:text=When%20furanose%20residues%20are%20part%20of,c%20and%20f%29%20are%20made%20of%20%5BHex-P-Hex-%5Dn'] bGSL:52d8ecbb-04fc-4b9c-a1f7-24919262c1f9 xylan heteroxylan 1C EOG_VARKI_4E Xylan is a class of hemicellulosic polysaccharides composed mainly of linear β1-4-linked D-xylose residues. Commonly found in plant cell walls, especially in secondary cell walls, xylans may be substituted with other sugars or chemical groups and are important structural components in plants. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch24/#:~:text=The%20expression%20of%20genes%20involved,function%20remains%20to%20be%20determined', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch59/#:~:text=Current%20research%20is%20focused%20on,125%20years%20%28the%20viscose%20process%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch08/#:~:text=Free-living%20fungi%20and%20the,the%20action%20of%20dozens%20of%20GTs', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch23/#:~:text=To%20convey%20the%20enormous%20diversity,plants%20and%20algae%20than%20in%20fungi.%20D', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch24/#:~:text=Glucuronoxylans%2C%20which%20are%20major,their%20reducing%20end%20%28Figure%2024.1C%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch40/#:~:text=More%20recently%2C%20additional%20plant,fungal%20and%20oomycete%20cell%20walls', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch48/#:~:text=The%20higher%20valency%20of%20IgM,glycan%20or%20nonglycan%20substituents'] bGSL:b0240e1d-1746-42ba-94ad-3a5d35485bfc xylogalacturonan 1C G00367NK EOG_VARKI_4E; GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE Xylogalacturonan is a class of plant cell wall pectic polysaccharides characterized by a homogalacturonan backbone with single β-D-xylose residues attached to the O-3 position of some galacturonic acid residues. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch24/#:~:text=Rhamnogalacturonan-I%20%28RG-I%29%20is%20a,of%20some%20of%20the%20backbone%20residues'] bGSL:c62e81b0-bd12-4a19-bf3c-2aab6c3502fd xyloglucan 1C G25326UC EOG_VARKI_4E; GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE Xyloglucan is a major hemicellulosic polysaccharide found in plant cell walls, consisting of a β-1,4-glucan backbone substituted with α-D-xylose and sometimes other sugars. It plays a key role in cell wall structure and expansion by acting as a tether between cellulose microfibrils. Oligosaccharide fragments derived from the enzymatic or chemical breakdown of xyloglucan can trigger defense responses in plants and provide protection against pathogens. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch40/#:~:text=Xyloglucan%20oligosaccharides,function%20as%20signaling%20molecules', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch40/#:~:text=This%20complex%20initiates%20a%20signaling,when%20applied%20exogenously%20to%20crops'] ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch59/#:~:text=Current%20research%20is%20focused%20on,125%20years%20%28the%20viscose%20process%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch08/#:~:text=Free-living%20fungi%20and%20the,the%20action%20of%20dozens%20of%20GTs', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch24/#:~:text=Each%20Xylp%20residue%20may%20itself%20be,plant%20growth%20and%20development', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch40/#:~:text=More%20recently%2C%20additional%20plant,fungal%20and%20oomycete%20cell%20walls'] bGSL:5ece904f-b068-4dfc-af78-801186adf756 α-mannan α-mannose-containing glycan 1C EOG_VARKI_4E A polysaccharide composed of a backbone of α1-6-linked mannose residues with α1-2-linked mannose side chains. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch34/#:~:text=MINCLE%20also%20maintains,yeast%20and%20fungal%20infections'] bGSL:be3c7543-e651-4301-aa30-1f0b7ebd7777 β-(1,3)-glucan β-1,3-glucan β-glucan 1C EOG_VARKI_4E β-(1,3)-glucan is a polysaccharide composed of glucose units linked by β-(1,3) glycosidic bonds. It can be linear or branched and is a major structural component of fungal and oomycete cell walls. β-(1,3)-glucan can also be released as oligosaccharides, which may function as pathogen-associated molecular patterns (PAMPs) in plants. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch12/#:~:text=GPI%20biosynthesis%20and%20transfer%20to,from%20detection%20by%20macrophages'] ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch40/#:~:text=In%20both%20rice%20and%20Arabidopsis%2C%20the,suppression%20of%20defense%20responses', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch40/#:~:text=The%20activities%20of%20such,oligosaccharides%20%28Figure%2040.2%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch40/#:~:text=More%20recently%2C%20additional%20plant,fungal%20and%20oomycete%20cell%20walls', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch40/#:~:text=This%20complex%20initiates%20a%20signaling,when%20applied%20exogenously%20to%20crops', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch40/#:~:text=Xyloglucan%20oligosaccharides,function%20as%20signaling%20molecules'] bGSL:4a59382e-7ba9-4a67-b902-2173b7eed790 β-(1,4)-glucan β-1,4-glucans β-glucan 1C EOG_VARKI_4E A polysaccharide composed of glucose residues linked by β-1,4-glycosidic bonds; it is the main structural component of cellulose in plant cell walls. Oligosaccharides released from cellulose can act as signaling molecules in plants. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch40/#:~:text=More%20recently%2C%20additional%20plant,fungal%20and%20oomycete%20cell%20walls', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch40/#:~:text=For%20example%2C%20%CE%B2-1%2C3-glucan,respectively%20%28Figure%2040.2%29'] bGSL:0e333cb5-e804-4f02-8a66-e08740db74c8 β-glucan glucan β-(1,3)-glucan; β-(1,4)-glucan; cyclic β1-2 glucan 1C G00024MO EOG_VARKI_4E; PUBDICT_GLYCAN_MOTIF; PUBDICT_MOTIF_GTC β-glucan refers to a class of polysaccharides made up of glucose monomers connected mainly by β-glycosidic bonds. These molecules are commonly found in the cell walls of fungi and plants, and they can exhibit structural diversity, including linear or mixed-linkage forms such as β-1,3 and β-1,4 linkages. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch12/#:~:text=It%20is%20clear%20that%20purified%20GPI-APs,by%20the%20actions%20of%20Dfg5%20and%20Dcw1', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch23/#:~:text=To%20convey%20the%20enormous%20diversity,plants%20and%20algae%20than%20in%20fungi.%20D', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch24/#:~:text=A%20small%20number%20of%20the%20backbone,produced%20by%20plants%20%28Figure%2024.1G%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch34/#:~:text=MBL%2C%20conglutinin%2C%20CL-43%2C%20CL-46%2C,is%20further%20augmented%20by%20SP-A', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch34/#:~:text=MINCLE%20also%20maintains,yeast%20and%20fungal%20infections'] bGSL:1370b15e-1986-436b-a607-01039130a7dc 3Su-Gal-4(Fuc)-GlcNAc 3'-sulfo Lewis x 2A BIOOLIGO bGSL:fda0a15a-0af5-4875-a87a-8d5cba8f7463 6-sialyl GalNAc sialyl Tn antigen 2A G08371CD; G73708UL GSD:00008 GlycoMotif:GGM.000035; GlycoMotif:CCRC.000035 GSD_GLYGEN_V1; GLYCOMOTIF_GGM; GLYCOMOTIF_CCRC; PUBDICT_GLYCAN_MOTIF An amino disaccharide composed of N-acetylneuraminic acid and 2-(acetylamino)-2-deoxy-D-galactopyranose residues joined by an (α-2→6) glycosidic bond.[CHEBI:146820] mmunohistochemical distributions of carbohydrate antigens based on the type 2 chain in normal as well as fetal and neoplastic tissues of human gastrointestinal tract were investigated with a monoclonal antibody (MAb) H11 (specific for type 2 chain) alone and in combination with the two MAbs MSG15 (for alpha 2----6 sialylated type 2 chain) and IB9 (for the alpha 2----6 sialylated type 2 chain and glycoproteins having NeuAc alpha 2----6Gal-NAc), and 188C1 (for short- and long-chain Lex antigens) and FH2 (for the long-chain Lex antigen). [PMID: 1618643] bGSL:30c72730-8f9f-449d-bdb1-4e081379f830 6P-Man3 6-phospho-Man3 2A BIOOLIGO bGSL:ae8ea606-2877-4738-9bdb-098c4e57e1b5 a-3Galactosyl-3Fucosyllactose Galactosyl lactose 2A BIOOLIGO bGSL:e0b58f6d-4d76-4de4-af38-056649173fe2 a-4Galactosyl-3Fucosyllactose Galactosyl lactose 2A BIOOLIGO bGSL:0098ae67-3d95-43d6-8b1d-24e2e149bbcf Chitohexaose chitohexose 2A BIOOLIGO bGSL:f32430a0-0556-408f-8fd7-d69f62322ad6 Chitopentaose chitopentose 2A BIOOLIGO bGSL:ce3b4fc7-3e2e-4f7c-9e93-c82f80bd9bb4 Chitotetraose deoxy Chitotetraose 2A BIOOLIGO bGSL:5cac3981-70ee-41dc-9022-f7d377c3bfea Chitotriose deoxy Chitotriose 2A BIOOLIGO bGSL:652ff74e-a7c8-4e35-aab1-250fdf7078ef deoxy Chitotetraose Chitotetraose 2A BIOOLIGO bGSL:e3ce6a5d-1b8c-4611-9c23-4465b7783c82 deoxy Chitotriose Chitotriose 2A BIOOLIGO bGSL:efcab8dd-7102-462d-a89c-69a1fe6eb757 Difucosyllactose 2A BIOOLIGO bGSL:58cab4df-fe08-4154-b7bc-413d72ea64b8 Disialosylpentaose Disialylated pentaose type 1 disialosyl globopentaosylceramide 2A BIOOLIGO bGSL:9bf9ae4a-593c-42e3-a15b-9b61d38ffd06 Fuc a(1-3) Lac-di-Nac LacdiNAc fucosylated lacdiNAc 2A BIOOLIGO bGSL:50fff09f-01b1-4cf6-ac08-615b64a71596 Fuc(a1-3)GalNAc(b1) 2A G57709BH GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:a4b6d3eb-8320-4e3f-b2ca-5398ac62a584 Fuc-(GlcNAc-Man-(Gal-GlcNAc-Man)-Man-GlcNAc)-GlcNAc 2A BIOOLIGO bGSL:3ee741a5-4c6a-4bed-9647-fb71e97f5d9f Fuc-Gal-Xyl 2A BIOOLIGO bGSL:ae4d9c45-f9fa-43fe-955c-0aac6630ed4d Fucα1-2Gal terminal fucose; terminal α-linked fucose 2A EOG_VARKI_4E A disaccharide composed of fucose linked α1-2 to galactose. This motif is commonly found as a terminal structure on host epithelial glycoconjugates, with its expression regulated by bacterial exposure and fucosyltransferase activity. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch42/#:~:text=This%20microbe%20has%20evolved,on%20the%20epithelium.%20B', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch42/#:~:text=When%20dietary%20fucose%20is%20low%2C%20the,are%20missing%20from%20the%20diet'] bGSL:b636f5dd-ada3-41f4-972b-c2c84b7e139c Gal b1-4 GalNAc b1-4 Gal b1-4 Glc Gal b1-4 GalNAc b1-4 Gal b1-4 Glc b 2A BIOOLIGO bGSL:62344029-9e31-462b-8106-8f3793417d53 Gal b1-4 GalNAc b1-4 Gal b1-4 Glc b Gal b1-4 GalNAc b1-4 Gal b1-4 Glc 2A BIOOLIGO bGSL:02b6234a-d385-4349-923f-32fa5f92151b Gal(b1-3)GalNAc Galβ1-3GalNAcβ1-4Gal 2A G58645HA; G78436BB GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:dc7c1890-4dae-4465-85fe-3e614da65008 Gal(b1-4)[Fuc(a1-3)]Glc(b1) 2A G41323BT; G57548NB GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:34418033-c36c-4e2d-a90e-e932d56429b1 Gal-GalNAc-(Neu5Ac)-Gal-Glc 2A BIOOLIGO bGSL:6bb11583-ab21-4d35-b9ed-e43c18cc2702 Gal-GlcNAc-(Gal-GlcNAc)-Gal 2A BIOOLIGO bGSL:2bda22c3-24ac-4ff1-95d6-7b28026d7d45 Gal-GlcNAc-Man-(Gal-GlcNAc-Man)-Man-GlcNAc 2A BIOOLIGO bGSL:51c94f88-a9dc-4417-8873-ffc3d6eee167 Galalpha1-3Gal Galα1-3Galα; alpha-gal antigen 2A G00046MO PUBDICT_MOTIF_GTC bGSL:dbc392c2-6493-4cbf-bf5a-5c8791e04eed GalNAc(b1-3)Gal(b1-4)GlcNAc 2A G61149BD GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:18c1af5a-1a20-478b-8f6e-b08cfdc6fc45 GalNAc(b1-4)[Neu5Ac(a2-3)]Gal(b1) 2A G45058HZ GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:5aaee846-564e-424b-926e-19c5bd3b06d9 GalNAc(b1-4)[Neu5Gc(a2-3)]Gal(b1) 2A G23581GL; G29406SZ GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:36a6913f-45f3-4ee4-b649-7f9ae84bf462 GalNAc(b1-4)Gal 2A G60859DF GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:7029e49f-d934-4a9e-a94d-f2831157c4b7 GalNAc-(Fuc)-Gal-Glc 2A BIOOLIGO bGSL:5b5c3518-3414-4c49-8011-0b9032c767f6 GalNAcα1-3Gal α(1-3)-linked N-acetylgalactosamine 2A EOG_VARKI_4E A disaccharide composed of N-acetylgalactosamine (GalNAc) α1-3 linked to galactose. This structure is found in blood group A antigens and certain glycolipids. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch44/#:~:text=An%20exception%20to%20this%20is%20the,in%20a%20highly%20ordered%20fashion'] bGSL:082eb622-5884-4fcf-87e7-49ca03ec6e7d GalNAcα1-4GalNAcα1-3-diNAcBac 2A EOG_VARKI_4E This is a trisaccharide fragment found in the Campylobacter jejuni N-glycan heptasaccharide, composed of GalNAcα1-4GalNAcα1-3-diNAcBac, where diNAcBac refers to 2,4-diacetamido-2,4,6-trideoxyglucopyranose. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch21/#:~:text=In%20C.%20jejuni%2C%20fOS%20concentrations,for%20triggering%20translocation'] bGSL:0e3465cb-3b05-4e02-9f78-020025770d71 GalNAcα1-4GalNAcα1-4 2A EOG_VARKI_4E A disaccharide composed of two N-acetylgalactosamine (GalNAc) residues linked via an α1-4 glycosidic bond; it is a component of the Campylobacter jejuni N-glycan heptasaccharide. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch21/#:~:text=In%20C.%20jejuni%2C%20fOS%20concentrations,for%20triggering%20translocation'] bGSL:de079c62-b645-4d58-aee7-5ad7f1eb0318 Galα1-3GalNAc 2A EOG_VARKI_4E A disaccharide composed of galactose alpha1-3 linked to N-acetylgalactosamine, commonly found as a terminal structure in mucin-type O-glycans. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch27/#:~:text=Indeed%2C%20developmental%20changes%20in,against%20microbial%20infection'] bGSL:ee4e9d22-2bc5-41c5-a4ca-9bb8a5493ffe Galα1-3Galα Galalpha1-3Gal alpha-gal antigen 2A EOG_VARKI_4E A disaccharide composed of two galactose residues connected by an alpha1-3 glycosidic bond. This structure is found as a capping motif on certain core trisaccharides in glycan structures. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch18/#:~:text=Skp1%20is%20an%20adaptor%20in%20SCF,disaccharide%20%28Figure%2018.2A%29'] bGSL:4f6c2584-5dd7-483d-bb94-a451f364afb9 Galα1-3Galβ1-4GlcNAc 2A EOG_VARKI_4E A trisaccharide composed of galactose alpha1-3 linked to galactose beta1-4 linked to N-acetylglucosamine. This structure is a common terminal motif in many mammalian glycans but is notably absent in Old World primates. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch20/#:~:text=Another%20unexplained%20phenomenon%20is,that%20synthesize%20this%20glycan', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch25/#:~:text=elegans.%20These%20may%20pertain%20to,Lewis%20x.%20The%20sheep%20parasite%20H'] bGSL:dc4bec69-854c-47f4-98b9-c7069fddffde Galα1-3Glcα Galα1-3Glcα1- disaccharide 2A EOG_VARKI_4E A disaccharide composed of galactose linked alpha1-3 to glucose (alpha anomer). It can be found as a capping structure on certain core trisaccharides. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch18/#:~:text=Skp1%20is%20an%20adaptor%20in%20SCF,disaccharide%20%28Figure%2018.2A%29'] bGSL:8a2f7aef-a1f0-4afa-9fc1-e5079050f59a Galβ1-3GalNAcβ1-4Gal Gal(b1-3)GalNAc 2A EOG_VARKI_4E A trisaccharide motif composed of galactose β1-3 linked to N-acetylgalactosamine, which is β1-4 linked to galactose. This structure is found as a component of gangliosides GM1b and GA1. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch31/#:~:text=In%20each%20subunit%2C%20the%20%CE%B1-%20and,of%20the%20ganglioside%20%28Chapter%2020%29'] bGSL:9c6bf643-a0d4-4c67-93c3-50af5c4f02b4 Galβ1-3GlcNAcβ1-3Galβ1-4GlcNAc 2A EOG_VARKI_4E This tetrasaccharide motif consists of galactose β1-3 linked to N-acetylglucosamine, which is β1-3 linked to galactose, itself β1-4 linked to N-acetylglucosamine. It is recognized by TRA-1-60 and TRA-1-81 antibodies as part of keratan sulfate–related antigens. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch41/#:~:text=For%20example%2C%20stage-specific,play%20key%20roles%20in%20hemostasis'] bGSL:d43a6a94-f622-4ab9-bf36-e7cf057c93ef GlcA-GlcNAc repeating unit GlcA-GlcNAc RUs 2A EOG_VARKI_4E A repeating disaccharide unit composed of glucuronic acid and N-acetylglucosamine, characteristic of the NAc-domains in glycosaminoglycans such as heparan sulfate. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch03/#:~:text=The%20conformational%20flexibility%20in,desired%20biological%20activities'] bGSL:fe9817b8-21fe-4d01-8332-87fe0e9b129c GlcAβ1-3GalNAc repeating unit 2A EOG_VARKI_4E A repeating disaccharide unit composed of glucuronic acid β1-3 linked to N-acetylgalactosamine, which forms the backbone structure of chondroitin sulfate glycosaminoglycans. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch38/#:~:text=Although%20CCL5%20is%20a%20small%20protein,end%20to%20build%20a%20filament%20structure'] bGSL:da019362-0ad6-463f-81bc-22c24724232c GlcAβ1-3Galβ 2A EOG_VARKI_4E A disaccharide epitope composed of glucuronic acid β1-3 linked to galactose, typically with a reducing end aglycone (R). It is recognized as the unsulfated HNK epitope. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch48/#:~:text=For%20the%20UDP-Gal%20transporter%20from,Lex%20and%20SLex%20%28for%20the%20%CE%B11-3%20FucT%29'] bGSL:7528a684-af89-4755-a221-692f36c99274 GlcNAc b(1-3') LacNAc GlcNAc(b1-3)Gal(b1-4)GlcNAc 2A BIOOLIGO bGSL:b7915434-16a1-49c5-a228-5f62b80942d6 GlcNAc b(1-4,6) GalNAc 2A BIOOLIGO bGSL:42790a3e-b5f2-4883-b9f5-3dc2303e6a10 GlcNAc(b1-3)Gal 2A G02880JU GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:d1663390-6185-4fdc-ac48-fd666fd483b0 GlcNAc(b1-3)Gal(b1-4)GlcNAc GlcNAc b(1-3') LacNAc 2A G48117BL GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:9030f946-bb03-4c68-905b-059ed2913fc8 GlcNAc-(Fuc)-GlcNAc 2A BIOOLIGO bGSL:91081009-e734-4e08-8c9d-f0941303d693 GlcNAc-Gal-Glc 2A BIOOLIGO bGSL:0d12d763-9aa7-453b-a52b-aee2ce9fa96a GlcNAc-Man-(GlcNAc-Man)-Man 2A BIOOLIGO bGSL:ddd78702-5821-4931-be11-07e345c62fcd GlcNAc-P-Man phosphodiester 2A EOG_VARKI_4E A glycan motif in which N-acetylglucosamine phosphate is linked to mannose through a phosphodiester bond. This structure is recognized by the cation-independent mannose 6-phosphate receptor. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch33/#:~:text=The%20first%20candidate%20%28%E2%88%BC275-kDa%29,and%20extensively%20characterized'] bGSL:648da1c3-6ca5-42a7-acad-96ee813edd67 GlcNAcβ1-2Manα1-3 β2-linked N-acetylglucosamine 2A EOG_VARKI_4E A disaccharide motif consisting of N-acetylglucosamine (GlcNAc) β1-2 linked to mannose, which is α1-3 linked to another sugar. This structure is commonly found in branched N-glycan structures. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch32/#:~:text=Yet%2C%20in%20other%20L-type%20lectins%2C%20no,%C3%85%20%28B%29%20complexed%20with%20Gal%CE%B21-4GlcNAc'] bGSL:33f8d633-8438-4b66-8971-620b17530153 GlcNAcβ1-2Manα1-6 β2-linked N-acetylglucosamine 2A EOG_VARKI_4E A disaccharide motif in which N-acetylglucosamine (GlcNAc) is β1-2 linked to mannose, which is α1-6 linked to another sugar. This structure is commonly found as part of branched N-glycan structures. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch32/#:~:text=Yet%2C%20in%20other%20L-type%20lectins%2C%20no,%C3%85%20%28B%29%20complexed%20with%20Gal%CE%B21-4GlcNAc'] bGSL:f43acc88-b4ad-4161-9ca0-963a902e0f82 GlcNAcβ1-4Gal β4-linked N-acetylglucosamine 2A EOG_VARKI_4E A disaccharide motif consisting of N-acetylglucosamine (GlcNAc) β1-4 linked to galactose. This structure is commonly found in both N-glycans and O-glycans. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch30/#:~:text=This%20energy%20results%20from,and%20questions%20to%20be%20answered'] bGSL:894ce1b6-7a91-400f-b6b7-41c1dbc01eab GlcNAcβ1-4Glc-Cer glycosylceramide; β4-linked N-acetylglucosamine 2A EOG_VARKI_4E A glycosphingolipid structure in which N-acetylglucosamine (GlcNAc) is β1-4 linked to glucose, and the glucose is attached to a ceramide moiety. This structure is found in certain invertebrates. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch20/#:~:text=In%20contrast%2C%20plants%20do%20not%20appear,deuterostome%20lineage%20of%20animals'] bGSL:bab09dfa-b003-4a2d-aaf0-b6bbd90e9b0d GlcNAcβ1-4GlcNAc β4-linked N-acetylglucosamine 2A EOG_VARKI_4E A disaccharide motif consisting of N-acetylglucosamine (GlcNAc) β1-4 linked to another GlcNAc. This structure is a common core component in N-glycans. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch18/#:~:text=Additional%20evidence%20shows%20that,outer%20member%20of%20the%20mitochondrion', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch06/#:~:text=Schematic%20representation%20of,mechanism%20%28Figure%206.5B%29'] bGSL:e35efdda-560a-4fbb-8e8d-a914f6f79817 GlcNAcβ1-4Man β4-linked N-acetylglucosamine 2A EOG_VARKI_4E A core disaccharide structure found in complex-type N-glycans, consisting of N-acetylglucosamine (GlcNAc) β1-4 linked to mannose (Man). This motif is produced by the enzyme MGAT3 and is recognized by the E-PHA lectin. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch48/#:~:text=L-PHA%20binding%20is%20dramatically,samples%20differ%20in%20glycosylation'] bGSL:e6b5ad78-6768-49ef-b501-727b88b8a66f Glcα1-4Glc repeating unit 2A EOG_VARKI_4E A repeating disaccharide unit of glucose (Glc) α1-4 linked to glucose, forming the linear backbone of glycogen and other α-glucans. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch05/#:~:text=Glycan%20salvage%20pathways%20are,by%20phosphorolysis%20of%20glycogen'] bGSL:7b94a67c-e421-49d4-adea-219893ee7fc4 Glcα1-phosphate-Man Glcα1-PO4-Man 2A EOG_VARKI_4E A glycosidic linkage in which glucose (Glc) is α1-linked to mannose (Man) through a phosphate group. This structure is associated with the activities of glucose phosphotransferase and Glc-1-phosphate phosphodiesterase. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch18/#:~:text=Further%20data%20show%20that%20several,the%20specific%20structures%20themselves'] bGSL:59ea9e40-8bfd-410c-9aa3-ae6d07ec0569 Glcβ1-3Fucα-O- O-fucose glycan; O-fucose core O-fucose glycan /Thrombospondin Type 1 Repeat 2A EOG_VARKI_4E A disaccharide modification found on O-fucosylated serine or threonine residues, where a glucose (Glc) is β1-3 linked to a fucose (Fuc) that is α-linked to serine or threonine. This structure is commonly present on thrombospondin type 1 repeats (TSRs). ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch13/#:~:text=Consistently%2C%20EOGT%20in%20mice,with%20defects%20in%20gastrulation'] bGSL:938cf5ad-4abb-428b-baf8-41d795c82bf5 Hyalonuric acid hexasaccharide hyaluronan 2A BIOOLIGO TRUE bGSL:dbdba54f-372a-4618-bba4-dbc2184f7476 Hyalonuric acid tetrasaccharide 2A BIOOLIGO TRUE bGSL:c4c1b7d6-8c76-4585-951f-f377f7309641 KDN-Gal 2A G82612XX; G82625KX GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:1bc67cd1-cc77-4f9d-a471-73987a59b11e Man a1-2 Man a1-6 Man a1-6 (Man a1-2 Man a1-3) Man b1-4 GlcNAc b1-4 GlcNAc b (Man)6 (GlcNAc)2 2A BIOOLIGO bGSL:8a4a1523-93cf-4c4a-bb53-5e6833ff7b33 Man a1-3 (Man a1-6) Man (Man)3a 2A BIOOLIGO bGSL:eacfe378-dc52-4f5f-8594-606e9637939a Manβ1-4Glc-ceramide Manβ1-4Glc-Cer 2A EOG_VARKI_4E A glycosphingolipid core structure found in certain invertebrates, consisting of a β1-4 linked mannose and glucose attached to a ceramide lipid. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch20/#:~:text=In%20contrast%2C%20plants%20do%20not%20appear,deuterostome%20lineage%20of%20animals'] bGSL:e54dd7e3-e139-47c9-a3eb-603f54d867aa Neu5Ac a2-6 Gal b1-4 GlcNAc b1-4 Gal b1-4 GlcNAc 2A BIOOLIGO bGSL:e2d09898-76c1-4b9f-8af9-720823ff8678 Neu5Ac(a2-3)Gal / Monosialoganglioside Neu5Ac(a2-3)Gal(b1-4)Glc 2A G77824XV GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCAN_IMAGE bGSL:46f60178-b1df-4060-a7f2-936364e5e79e Neu5Ac(a2-3)Gal(b1-3)GalNAc 2A G56299XO GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:f8204924-12f4-40e8-8eeb-cca8fd109a11 Neu5Ac(a2-3)Gal(b1-4)Glc Neu5Acα2-3Gal; Neu5Ac(a2-3)Gal / Monosialoganglioside 2A G56516VH GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; BIOOLIGO bGSL:1ec01d59-be74-46df-b828-c09f2a36be17 Neu5Ac(a2-3)Gal(b1-4)GlcNAc Neu5Acα2-3Gal 2A G10203DW GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:109475c1-065e-4c2e-aef3-dd88d807c2da Neu5Ac(a2-6)GalNAc 2A G08371CD GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:11e5c98d-4683-4c15-9489-17b04e920c8e Neu5Ac(a2-8)Neu5Ac(a2-3)Gal 2A G43195TR; G82775QT GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:00a3842f-cd08-4fc3-9de1-5a6edd34bfab Neu5Ac(a2-8)Neu5Ac(a2-3)Gal(b1-3)GalNAc a2-3 Neu5Ac on Core 1 2A G93910CU GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:564d7b4c-768a-45fd-b810-01a320d1a383 Neu5Ac(a2-8)Neu5Ac(a2-3)Gal(b1-4)Glc 2A G81928IQ GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:30222ab3-ce71-4731-9db7-9251f0ebcd82 Neu5Ac(a2-8)Neu5Gc(a2-3)Gal Neu5Ac(a2-8)Neu5Gc(a2-3)Gal(b1-4)Glc 2A G82974JM GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:3fd873d5-6d46-4426-b243-b00c844d598e Neu5Ac(a2-8)Neu5Gc(a2-3)Gal(b1-4)Glc Neu5Ac(a2-8)Neu5Gc(a2-3)Gal; Neu5Gcα2-3Galβ1-4Glc 2A G95233MF GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:790f808b-fb3c-41ce-894b-b2e6f7f64cac Neu5Ac-Gal-(Fuc)-GlcNAc Neu5Ac-Gal-(Fuc)-GlcNAc-OMe 2A BIOOLIGO bGSL:1d72313e-ac00-4bfd-8719-d395f8534b84 Neu5Ac-Gal-(Fuc)-GlcNAc-OMe Neu5Ac-Gal-(Fuc)-GlcNAc 2A BIOOLIGO bGSL:5456a3bb-976a-4c5d-bb5b-dd7c97b92317 Neu5Ac-Gal-(Neu5Ac)-deoxy-GalNAc 2A BIOOLIGO bGSL:241bed3a-84eb-44b8-9174-f5bdb38f060f Neu5Ac-Gal-(Neu5Ac)-GlcNAc 2A BIOOLIGO bGSL:072d213d-73a3-43bf-a1c7-391f057fa974 Neu5Acα2-3Gal Neu5Acα2–3Gal- Neu5Ac(a2-3)Gal(b1-4)Glc; Neu5Ac(a2-3)Gal(b1-4)GlcNAc 2A G30207PZ EOG_VARKI_4E; GLYCOEPITOPE; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE Neu5Acα2-3Gal is a disaccharide motif where N-acetylneuraminic acid (Neu5Ac) is linked in an alpha 2-3 configuration to galactose (Gal). This structure is commonly found as a terminal motif on glycans and is recognized by certain viruses and lectins. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch35/#:~:text=This%20mechanism%20was%20first%20seen%20with,of%20which%20could%20function%20as%20ITIMs', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch37/#:~:text=Thus%2C%20the%20specificity%20of%20the,hemagglutinin%20%28HA%29%20ectodomain', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch37/#:~:text=The%20specificity%20of%20the%20host,to%20species%20and%20target%20cells', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch37/#:~:text=This%20adhesin%20preferentially%20binds,or%20maintain%20these%20relationships'] bGSL:f2f88ca2-2fec-4eea-a97e-7f912855ee01 Neu5Acα2-6Gal 2A G44345UH; G63069TR EOG_VARKI_4E; GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE Neu5Acα2-6Gal is a disaccharide motif consisting of N-acetylneuraminic acid (Neu5Ac) linked in an alpha 2-6 configuration to galactose (Gal). This structure is commonly found as a terminal motif on human airway epithelial cell glycans and serves as a receptor determinant for certain viruses. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch37/#:~:text=The%20specificity%20of%20the%20host,to%20species%20and%20target%20cells', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch37/#:~:text=This%20adhesin%20preferentially%20binds,or%20maintain%20these%20relationships'] bGSL:6f247dfb-923c-487a-baa2-6ebf31138072 Neu5Gc(a2-3)Gal / Monosialoganglioside Neu5Gcα2-3Galβ1-4Glc Neu5Gcα2-3Galβ1-4Glc 2A G53517XC GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:284524da-dbc9-4688-8d2b-3c637d53fb0f Neu5Gc(a2-3)Gal(b1-4)GlcNAc 2A G48236KP GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:28effa2b-ca0d-40ee-8e28-bd2704afd9c4 Neu5Gc(a2-8)Neu5Ac(a2-3)Gal 2A G55286YY; G61424BA GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:0a15629b-adab-4134-85e1-4bb472f82e63 Neu5Gc(a2-8)Neu5Gc(a2-3)Gal 2A G16142UJ; G16775IT GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:b222a96d-63f2-4493-8e44-a0b2b5161c1c Neu5Gcα2-3Galβ1-4Glc Neu5Gcα2–3Galβ1–4Glc Neu5Gc(a2-3)Gal / Monosialoganglioside Neu5Gc(a2-3)Gal / Monosialoganglioside; Neu5Ac(a2-8)Neu5Gc(a2-3)Gal(b1-4)Glc 2A G32969VW EOG_VARKI_4E; GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE This trisaccharide consists of N-glycolylneuraminic acid (Neu5Gc) linked α2-3 to galactose (Gal), which is β1-4 linked to glucose (Glc). It is found in certain glycolipids and is recognized by specific bacterial strains. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch37/#:~:text=The%20fine%20specificity%20of%20bacterial,AB5%2C%20has%20been%20extensively%20studied'] bGSL:da2a9a28-18ba-4b91-abb7-f16ef42a7276 Sai2-3Gal Siaα2-3Galβ1-4GlcNAc 2A G77824XV; G30207PZ SUGARBIND bGSL:bad7846f-0e8c-4f47-81cc-7e0f0bd3f67e Sia(a2-8)Sia(a2-3)Gal 2A G82775QT PUBDICT_GLYCAN_MOTIF bGSL:c9a40c45-e062-4377-a7c4-7cf616ba0c8a Sialylparagloboside NeuAca2-6PG; IV6(NeuAc)nLc4Cer 2-6 sialylparagloboside 2A G83513YI SUGARBIND; PUBDICT_GLYCAN_MOTIF bGSL:77611377-5dc6-4ad5-a8d5-80876bf793df Siaα2-3Galβ1-4GlcNAc α2-3 sialic acid branch; Sai2-3Gal sialosyl paragloboside α2-3 sialyllactosamine; 3'-sialyl-LacNAc (type 2) 2A EOG_VARKI_4E A trisaccharide glycan structure where sialic acid (Sia) is α2-3 linked to galactose (Gal), which is β1-4 linked to N-acetylglucosamine (GlcNAc). This structure can be formed by elongation of O-GlcNAc with β1,4Gal followed by sialylation. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch13/#:~:text=Recently%2C%20a%20second%20%CE%B2-linked,to%20form%20Sia%CE%B12-3/6Gal%CE%B21-4GlcNAc'] bGSL:c54dc948-e519-44e8-abd5-9c78de1e2c91 Siaα2-6Galβ1-4GlcNAc 2-6 Sialyl-LacNAc-Gal 2A EOG_VARKI_4E A trisaccharide glycan structure consisting of sialic acid (Sia) α2-6 linked to galactose (Gal), which is β1-4 linked to N-acetylglucosamine (GlcNAc). This motif is recognized by CD22 on B lymphocytes. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch14/#:~:text=Mice%20lacking%20ST6GAL1%20show,members%2C%20and%20perhaps%20other%20lectins', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch13/#:~:text=Recently%2C%20a%20second%20%CE%B2-linked,to%20form%20Sia%CE%B12-3/6Gal%CE%B21-4GlcNAc'] bGSL:3ee62d74-c45b-4e1e-867f-7b35f9055c9b Tk 2A BIOOLIGO bGSL:3b3e88f3-3041-4c36-bc77-0ff9659e96e5 trehalose-6,6-dimycolate 2A EOG_VARKI_4E A glycolipid composed of a trehalose disaccharide esterified at both 6-positions with mycolic acids. It serves as a key virulence factor in Mycobacterium tuberculosis and Mycobacterium bovis. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch34/#:~:text=Mice%20have%20the%20Ly49%20family%20of,immune%20responses%20against%20infection'] bGSL:ee8eeebe-92dd-4cca-8261-08a52adf0abb α(2-6)sialylÂ_ lactotetraosylceramide Sialyllactotetraosylceramide 2A PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV bGSL:72446ac5-4435-4711-9317-16873c4a65b9 α(1-3)-linked N-acetylgalactosamine α(1-3)GalNAc N-acetylgalactosamine GalNAcα1-3Gal 2A EOG_VARKI_4E A terminal N-acetylgalactosamine (GalNAc) residue linked via an alpha(1-3) glycosidic bond, as found in the A blood group antigen tetrasaccharide. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch36/#:~:text=The%20binding%20preference%20of,N16%2C%20and%20the%20CRDs%201%E2%80%934%20of%20CvGal1'] bGSL:fe3dde7f-601d-48b4-b386-41757ec4a92e α(1-6)-linked glucose branch 2A EOG_VARKI_4E Branches in glycogen that consist of glucose units connected by α(1–6) glycosidic bonds, appearing periodically along the main α(1–4)-linked glucose chain. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch05/#:~:text=Glycan%20salvage%20pathways%20are,by%20phosphorolysis%20of%20glycogen'] bGSL:0ff3d118-dae8-42e8-9369-82ef9cbd58ea α-linked polyglucose amylose 2A EOG_VARKI_4E A polymer of glucose residues linked by alpha glycosidic bonds, forming nanofilaments such as those observed in the mitochondrial dividing ring of certain algae. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch18/#:~:text=Indeed%2C%20there%20is%20evidence%20for,elements%20of%20the%20secretory%20pathway'] bGSL:d1c3fa67-d245-401e-9cfa-663633f8d989 α2-3 sialic acid branch α2-3Sia branch Siaα2-3Galβ1-4GlcNAc 2A EOG_VARKI_4E A sialic acid residue linked in an α2-3 configuration that is present as part of a branched glycan structure, such as found on ganglioside GM2. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch15/#:~:text=pneumoniae%29.%20The%20products%20of,have%20not%20been%20well%20investigated'] bGSL:a7132805-2224-4bf9-995e-c6cfe8684a76 α2-3 sialyllactosamine α2-3sialyllactosamines sialylated N-acetyllactosamine; N-acetyllactosamine (type 2) Sulfated sialyl-3-N-acetyllactosamine Siaα2-3Galβ1-4GlcNAc; 3'-sialyl-LacNAc (type 2) 2A EOG_VARKI_4E A disaccharide motif consisting of sialic acid linked α2-3 to lactosamine (Galβ1-4GlcNAc), commonly found in glycoproteins and glycolipids, and produced by group B streptococci. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch21/#:~:text=However%2C%20some%20CPSs%20in%20important,members%20of%20the%20gut%20microbiota'] bGSL:a01f51e3-6658-40ce-9bd3-1d672b2e47b0 β-(1,4)-mannuronate 1-4-linked β-D-mannuronic acid 2A EOG_VARKI_4E A polysaccharide or oligosaccharide unit composed of mannuronic acid residues linked by β-1,4-glycosidic bonds; these structures form part of alginate, a major component of some bacterial and algal extracellular matrices. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch53/#:~:text=%28A%29%20Schematic%20overview%20of,strong%20base%20and%20hydrogenolysis'] bGSL:fa634421-7b48-4487-b92c-4be8f03816bf β-linked galactose β-linked Gal Gal beta1 β6-linked galactose; terminal β-linked galactose 2A G65889KE; G68158BT EOG_VARKI_4E; GLYCOEPITOPE; SUGARBIND; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE A galactose residue attached to another sugar or molecule via a β-glycosidic bond; commonly found as a terminal or internal residue in glycans recognized by galectins and other lectins. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch18/#:~:text=Furthermore%2C%20recent%20evidence%20shows,and%20in%20the%20pericellular%20matrix', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch15/#:~:text=Alternately%2C%20the%20same,type%2C%20tissue%20type%2C%20and%20species', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch06/#:~:text=The%20human%20fucosyltransferases,unusual%20flexibility%20in%20specificity', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch28/#:~:text=Small%20soluble%20lectins%20specific%20for,GBP%20isolated%20from%20a%20microorganism'] bGSL:78c9d1d4-526b-426e-9418-f3d68fe6a4e7 β-linked Kdo 2A EOG_VARKI_4E A residue of 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) linked via a β-glycosidic bond, commonly found in the oligosaccharide portion of bacterial glycolipids, such as those present in E. coli capsular polysaccharides. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch21/#:~:text=However%2C%20streptococcal%20CPS%20can,and%20-negative%20species'] bGSL:1b704471-d5ac-4b5d-aab0-8d417debe73c β2-linked mannose polymer 2A EOG_VARKI_4E A homopolymer of mannose residues linked via β1-2 glycosidic bonds, characteristic of the mannogen polysaccharide produced by Leishmania parasites. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch18/#:~:text=Glycogenin-like%20proteins%20are%20found,localized%20mannogen%20synthase'] bGSL:a2456a79-5101-437c-949f-84cbed3ffd89 β2-linked N-acetylglucosamine β1-2GlcNAc β-N-acetylglucosaminide GlcNAcβ1-2Manα1-6; GlcNAcβ1-2Manα1-3 2A EOG_VARKI_4E A structural motif where N-acetylglucosamine is linked via a beta-1,2-glycosidic bond, commonly found on the α1-3-mannose arm of N-glycans and known to influence fucosyltransferase substrate specificity. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch25/#:~:text=Furthermore%2C%20there%20is%20no%20evidence,by%20the%20presence%20of%20%CE%B11-6-mannose'] bGSL:8d1d73d7-26b3-4e92-a780-d2bf2a94a5cb β3-linked glucose 1-3-linked β-Glc 2A EOG_VARKI_4E β-D-glucose residues connected through 1-3 glycosidic bonds, commonly found in oligoglucosides that are components of cell wall polysaccharides. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch40/#:~:text=The%20activities%20of%20such,oligosaccharides%20%28Figure%2040.2%29'] bGSL:4fc9d8dc-8018-4fbe-bdbd-580b4d8d6687 β4-linked N-acetylgalactosamine β1-4GalNAc terminal β-linked N-acetylgalactosamine; β-N-acetylgalactosaminide 2A EOG_VARKI_4E A structural motif in which N-acetylgalactosamine is attached through a beta-1,4-glycosidic bond. This linkage is recognized as an antennal modification on N-glycans, such as those found in sea urchins. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch27/#:~:text=However%2C%20its%20receptor%20on%20the%20sperm,%28Figure%2027.2%29'] bGSL:0db24541-504f-4074-83e3-91114c51ff7f β4-linked N-acetylglucosamine β1-4GlcNAc β-N-acetylglucosaminide GlcNAcβ1-4Glc-Cer; GlcNAcβ1-4Gal; GlcNAcβ1-4GlcNAc; GlcNAcβ1-4Man 2A EOG_VARKI_4E A structural motif in which N-acetylglucosamine is attached via a beta-1,4-glycosidic bond, typically to mannose on N-glycans, forming the characteristic bisecting GlcNAc feature. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch47/#:~:text=Increased%20expression%20of%20FUT8%20that,depend%20on%20tissue%20context'] bGSL:c4b35dc1-c093-4b87-8f2c-4eb05ac5ede3 β6-linked galactose 1-6-linked β-Galp β-linked galactose; Galactose 2A EOG_VARKI_4E β-D-galactose residues connected through 1-6 glycosidic bonds, commonly present as side chains in branched galactan structures. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch24/#:~:text=The%20expression%20of%20genes%20involved,function%20remains%20to%20be%20determined'] bGSL:e2288562-a3da-471f-b9a3-9758a51428c7 β6-linked glucose 1-6-linked β-Glc 2A EOG_VARKI_4E β-D-glucose residues linked via 1-6 glycosidic bonds, commonly found in oligoglucosides released from cell walls by endo-glucanases. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch40/#:~:text=The%20activities%20of%20such,oligosaccharides%20%28Figure%2040.2%29'] bGSL:c501a131-1300-4316-aa62-693c8e27a725 β6-linked N-acetylglucosamine β1-6GlcNAc β-N-acetylglucosaminide; N-acetylglucosamine 2A EOG_VARKI_4E A β(1-6)-linked N-acetylglucosamine residue that is transferred by core 2 β1-6GlcNAcT enzymes (CGNT1, 3, and 4) during the biosynthesis of core 2 O-GalNAc glycans. This residue often serves as the branching point for poly-LacNAc extensions in mucin glycoproteins. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch14/#:~:text=Similarly%2C%20poly-LacNAc%20extensions,Gal%20engagement%20%28Chapter%2036%29'] bGSL:bbda9fd3-f7bf-4ea7-bb02-43bff1deb39d 1-4-linked α-L-guluronic acid 1-4-linked α-L-GulpA; 1,4 α-L-guluronic acid 2B EOG_VARKI_4E α-L-guluronic acid residues connected through 1-4 glycosidic linkages, forming a structural unit commonly found in alginate polysaccharides produced by brown seaweed. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch24/#:~:text=These%20polysaccharides%20are%20composed,and%20antitumor%20activities'] bGSL:ec4af692-6de4-4ab3-839f-7f2c63aef621 1-4-linked β-D-mannuronic acid 1-4-linked β-D-ManpA; 1,4 β-D-mannuronic acid β-(1,4)-mannuronate 2B EOG_VARKI_4E β-D-mannuronic acid residues connected through 1-4 glycosidic linkages, commonly found as a structural component in alginate polysaccharides produced by brown seaweed. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch24/#:~:text=These%20polysaccharides%20are%20composed,and%20antitumor%20activities'] bGSL:25bd7a44-2e9f-46da-aa83-d1fbed778a0a 2,6-branched O-mannose 2,6-branched O-mannosyl glycan O-glycans; α-mannose-containing glycan O-mannose core M2 2B G56868BH; G06953DR GSD:00168 GlycoMotif:GGM.000056; GlycoMotif:GDV.000109 GSD_GLYGEN_V1; CUMMINGS; GLYCOMOTIF_GGM; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF (2S,4S,5R,6R)-5-Acetamido-2-[(2S,3R,4S,5S,6R)-2-[(2R,3S,4R,5R,6R)-5-acetamido-6-[[(2R,3S,4S,5S,6S)-5-[(2S,3R,4R,5S,6R)-3-acetamido-5-[(2S,3R,4S,5S,6R)-4-[(2S,4S,5R,6R)-5-acetamido-2-carboxy-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxan-2-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,4,6-trihydroxyoxan-2-yl]methoxy]-4-hydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid.[CHEBI:157265] Collectively, these results strongly suggest that GnT-IX may be a novel beta1,6-N-acetylglucosaminyltransferase that is responsible for the formation of the 2,6-branched structure in the brain O-mannosyl glycan.[PMID:14617637] bGSL:58e03429-635d-4902-b73e-c85da9477359 C-mannose C-linked mannose 2B EOG_VARKI_4E A glycan modification in which a mannose residue is attached through a carbon-carbon (C-glycosidic) bond, most commonly found on tryptophan residues within thrombospondin type 1 repeats (TSRs) and certain complement proteins. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch13/#:~:text=It%20is%20expressed%20in%20many%20cells%20and,and%20F-spondin%20%28Table%2013.1%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch13/#:~:text=Note%20that%20this%20is%20a%20rare,consensus%20sites%20are%20fully%20modified'] bGSL:3cc075df-675f-45fb-89af-6ba252592673 desialylated glycan asialylated asialylated biantennary N-glycan 2B GSD:00042 GSD_GLYGEN_V1 A glycan from which sialyl groups have been removed. [https://en.wiktionary.org/wiki/desialylated] "Furthermore, we found no evidence for ""desialylated"" apoB100 glycans in any of the samples analyzed.[PMID:11588155]" bGSL:81c769ca-48df-4dbb-84c4-0bfb5e205535 fucosylated glycan fucosylated N-glycan; fucosylated tetraantennary N-glycan; fucosylated triantennary N-glycan; fucosylated trisialylated triantennary N-glycan; fucosylated biantennary N-glycan; 2-fucosyl GD1b; fucosylated disialylated biantennary N-glycan; fucosylated asialo-biantennary N-glycan 2B EOG_VARKI_4E Fucosylated glycans are glycans that contain fucose residues, typically attached through α1-2, α1-3, or α1-4 linkages. These structures play important roles in biological processes such as host-pathogen interactions and cell signaling. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch03/#:~:text=As%20molecules%2C%20they%20are%20generally,little%20or%20none%20of%20this%20compound', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch05/#:~:text=It%20is%20especially%20difficult%20to,pools%20and%20glycosyltransferases', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch14/#:~:text=There%20is%20a%20relatively%20high,of%20these%20abundant%20glycans', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch37/#:~:text=As%20such%2C%20these%20toxins%20function%20by,on%20the%20surface%20of%20host%20cells'] bGSL:bff34cf6-6661-4a15-b1b6-64fc41101f95 fucosylated N-glycan fucosylated glycan fucosylated tetraantennary N-glycan; fucosylated biantennary N-glycan; fucosylated disialylated biantennary N-glycan; fucosylated asialo-biantennary N-glycan; difucosylated tetraantennary N-glycan; fucosylated trisialylated triantennary N-glycan 2B GSD:00056 GSD_GLYGEN_V1; EOG_VARKI_4E The fucose from GDP-fucose is transferred to N-linked glycans. Haptoglobin , an acute phase protein , has four potential N-glycosylation sites , although it remains unknown which site is responsible for the change in fucosylated N-glycans.[PMID:18214858] bGSL:c5a910a4-c288-4111-a743-193019303ad6 Man-6-P-containing N-glycan 2B EOG_VARKI_4E N-glycans that contain mannose-6-phosphate (Man-6-P) residues. These glycans were first identified on lysosomal enzymes and are essential for proper lysosomal trafficking, serving as recognition markers for targeting enzymes to lysosomes. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch07/#:~:text=These%20glycans%20have%20potent%20effects,for%20different%20functional%20roles', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch44/#:~:text=Iduronic%20acid-2-sulfatase,Junko%20Matsuda%20and%20Nathan%20Lewis'] bGSL:fc397449-595b-470c-946c-1838abd1eb14 mannose-terminated N-glycan terminal mannose paucimannose N-glycan; high-mannose N-glycan 2B EOG_VARKI_4E A type of N-linked glycan characterized by mannose residues at its non-reducing ends. These glycans play a role in targeting proteins to specific cells, such as macrophages, by serving as recognition signals. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch44/#:~:text=A%20potential%20problem%20is%20that%20some,and%20hematological%20pathologies'] bGSL:837aca43-5e36-4324-be97-d787e6a30259 monoantennary N-glycan 2B EOG_VARKI_4E A monoantennary N-glycan is an N-glycan structure characterized by having a single antenna (branch) extending from the core. This type of glycan is often produced in engineered CHO cells, is typically unsialylated, and features exposed galactose acceptor sites. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch56/#:~:text=The%20process%20is%20in%20use%20with,the%20initiation%20of%20O-GalNAc%20glycans'] bGSL:d1fcc29c-653b-4096-9ffa-80d27a47e867 monoglucosylated N-glycan high-mannose N-glycan 2B EOG_VARKI_4E A high-mannose-type N-glycan containing a single glucose residue. This structure is recognized by calnexin and calreticulin in the endoplasmic reticulum and plays a key role in the glycoprotein folding quality control system. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch32/#:~:text=Although%20CRT%20is%20a%20soluble%20ER,or%20aggregated%20glycoproteins', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch39/#:~:text=Consequently%2C%20the%20GII%20activity,specificities%20are%20not%20identical', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch28/#:~:text=These%20interactions%20can%20take,ER%20until%20they%20are%20correctly%20folded'] bGSL:9460c9b1-c429-4d08-98b8-e4ca0bf7ba18 monosialylated ganglioside 2B EOG_VARKI_4E A ganglioside that contains a single sialic acid residue, such as GM3. These structures typically terminate in Neu5Acα2-3Gal and can be recognized by certain lectins, including those involved in HIV interactions. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch35/#:~:text=This%20mechanism%20was%20first%20seen%20with,of%20which%20could%20function%20as%20ITIMs'] bGSL:86aeecb7-17ce-4324-80b1-5954bf90b758 monosialylated N-glycan monosialylated biantennary N-glycan 2B GSD:00104 GSD_GLYGEN_V1 A glycan that have the addition of one sialic acid residues. The structures of the asparagine-linked sugar chains of U- CD59 were biantennary complex type , only 4.2% of which are monosialylated.[PMID:7514386] bGSL:3f08f99c-bdc0-479d-86b3-cfd2590dddf8 nonfucosylated N-glycan 2B GSD:00114 GSD_GLYGEN_V1 glycans without a fucose component/monosaccharide residue. In the carbohydrate moiety , alpha-subunit from normal pregnancy hCG contained nonfucosylated , mono- and biantennary N-linked structures (49.3 and 36.7%, means); fucosylated biantennary and triantennary oligosaccharides were also identified (7.3 and 6.9%).[PMID:9449027] bGSL:2cd43fb1-125f-4c74-b410-7ecc278e8fbd nonsialylated N-glycan asialylated biantennary N-glycan 2B GSD:00117 GSD_GLYGEN_V1 A glycan which is not sialylated. The pattern of nonsialylated oligosaccharides was used for interpretation of the fully sialylated species using bioinformatics tools. From pooled human plasma, we find 90, 101, and 64 different glycan compositions for genetic variants ORM1*F1, ORM1*S, and ORM2, respectively. Glycan structures carry dominantly between 15 and 16 sialic acids indicating an almost complete termination of all antenae with sialic acid.[PMID:30295034] bGSL:71cb5799-c7e8-4642-8483-45393fe99034 O-fucose core O-Fucose Core 1; O-Fucose Core Thrombospondin Type 1; O-Fucose Core 2; O-Fucose Core EGF Type O-fucose glycan /Thrombospondin Type 1 Repeat; Glcβ1-3Fucα-O- 2B G08324ZK; G85661BQ; G49112ZN; G82576YO GlycoMotif:GGM.001020; GlycoMotif:GGM.001021; GlycoMotif:GGM.001035 GLYCOMOTIF_GGM; PUBDICT_GLYCAN_MOTIF bGSL:4eb87bac-f926-4f1c-82dd-a9f3cc7f90d6 O-fucose glycan O-glycan; O-glycans; O-fucose glycan /Thrombospondin Type 1 Repeat Glcβ1-3Fucα-O-; O-fucose glycan /EGF Repeat 2B G39294YF GSD:00118 GSD_GLYGEN_V1; EOG_VARKI_4E Form of glycosylation where the protein is modified by a fucose residue and can be extended futher to form a tetrasaccharide in certain cases. alpha-linked o-fucose have a consensus motif of C2X4(s/T)C3 where C2 and C3 are conserved cysteines number 2 and 3 respectively of the EGFR like repeats. [Essentials of Glycobiology:Chapter13] Recently, a number of laboratories have shown that O-fucose glycans on the epidermal growth factor (EGF)-like repeats of the Notch extracellular domain modulate Notch signaling.[PMID:12417415] bGSL:0addc91e-6435-4463-8625-6ed69bf54db1 O-GlcNac glycan O-linked GlcNAc; O-β-GlcNAc; O-linked N-acetylglucosamine O-glycan; N-acetylglucosamine 2B G49108TO; G89565QL GSD:00119 GlycoMotif:GGM.001028 GSD_GLYGEN_V1; EOG_VARKI_4E; GLYCOEPITOPE; GLYCOMOTIF_GGM; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE Form of glycosylation which exclusively occurs in the mitochondrial, cytoplasmic or nuclear compartments of the cell where the protein is modified by a GlcNAc monosaccharide on the serine or threonine residues and is generally not modified or elongated further to form more complex structures. [Essentials of Glycobiology:Chapter19] A better understanding of the mechanisms of OGT/OGA action would enable us to derive therapeutic benefits of resetting cellular O-GlcNAc levels within an optimal range.[PMID:30464755] bGSL:fca9e765-7867-47f3-8a8a-e31c287a30ba O-glucose glycan O-Glc glycan 2B G71142DF GlycoMotif:GGM.001031 EOG_VARKI_4E; GLYCOMOTIF_GGM O-Glc glycans are glycans composed of a single glucose residue that is O-linked to serine or threonine residues of proteins. This type of O-glycosylation is found in various glycoconjugates and represents a simple form of protein glycosylation. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch56/#:~:text=Large%20libraries%20of%20isogenic%20cells,and%20TALEN-mediated%20gene%20knockout'] ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch26/#:~:text=As%20in%20mouse%20and%20humans%2C%20Drosophila,Shams%20and%20Xxylt%20%28Figure%2026.3%29'] bGSL:4afb57c3-f31e-4e02-af5f-138a49ac262c O-glycan O-fucose glycan; O-glycan core 2; O-glycan core 4; O-glycan core 3; O-GlcNac glycan O-glycans 2B GSD:00120 GSD_GLYGEN_V1 The carbohydrate portion of a glycoprotein that has a glycan linked through the hydroxyl oxygen of serine, threonine, hydroxylysine or hydroxyproline side-chains.[CHEBI:59521] Among these, six fucosylated N-linked glycansand four O-linked glycans exhibited significantly increased expression levels in GC, while five fucosylated N-linked glycans and ten fucosylated O-linked glycans exhibited significantly decreased expression levels in GC.[PMID:29865036] bGSL:38007c47-00b6-43c7-8505-9b3329cf56d5 O-mannose core O-mannose core M1; O-mannose core M3; O-mannose core M2 2B G76001GO GlycoMotif:GGM.001036 GLYCOMOTIF_GGM bGSL:5440ecf1-fc54-4536-aba2-747de9f5603b O-mannose glycan O-mannosyl glycan; O-Man glycan; O-mannose-based glycan; O-mannose initiated glycans O-glycans; α-mannose-containing glycan tri-mannose / O-linked; O-mannose glycan / mammalian; O-mannose glycan / yeast 2B G59126YU; G23707SD; G70323CJ GSD:00121 GlycoMotif:GGM.000055; GlycoMotif:GGM.001019; GlycoMotif:GDV.000110 GSD_GLYGEN_V1; EOG_VARKI_4E; CUMMINGS; GLYCOMOTIF_GGM; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF O-linked glycans that are initiated by the addtion of a Man residue to Ser or Thr. Subsequent extension of the Man defines the O-Man core type, either M1, M2, or M3. The M1 type is initated by addition of a GlcNAc in β-linkage to the 2 position of the Man residue. M2 is initiated by addition of another GlcNAc to the 6 position of the M1 core. M3 is initiated by the addition of a GlcNAc in β-linkage to the 4 position of the Man residue. M1 and M2 type core glycans can be extended and branched with Gal, Fuc, Sialic Acid, and GlcA. The M3 core is uniquely extended by a multienzyme system to generate the matriglycan polysaccharide, a protein-specific modification found only on alpha-dystroglycan. [CHEBI:87761] Protein O-linked mannose beta-1,4-N-acetylglucosaminyltransferase 2 (POMGNT2) catalyzes the first step toward the functional matriglycan structure on alpha-dystroglycan that is responsible for binding extracellular matrix proteins and certain arenaviruses.[PMID: 27932460] bGSL:0bff75bd-a018-429e-ba96-dc1334c65ebc S-linked glucose S-linked Glcp 2B EOG_VARKI_4E A glucose residue attached through a sulfur atom (S-glycosidic bond) rather than the usual oxygen linkage. This type of linkage is found in compounds such as glucosinolates and can be released by the action of myrosinase. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch24/#:~:text=Glycosylated%20secondary%20metabolites%20often,naringin%2C%20a%20glycosylated%20flavonoid'] bGSL:d4f3f0c5-e4e8-4c14-b06b-9b332c83a54e sialylated glycolipid sialofucosylated glycolipid; sialopentaosylceramide; ganglioside sialoglycolipid 2B EOG_VARKI_4E Glycolipids that contain sialic acid residues, which are recognized by myelin-associated glycoprotein and play a role in the inhibition of neuronal sprouting. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch41/#:~:text=The%20unusual%20polysialic%20acid%20chains,prevent%20neuronal%20regeneration'] bGSL:7e09b315-298c-4af0-a76d-441f94b2b543 sialylated N-glycan sialylated tetraantennary N-glycan; sialylated complex-type N-glycan 2B EOG_VARKI_4E Sialylated N-glycans are N-linked glycans that possess terminal sialic acid residues. These structures are commonly found on glycoproteins, such as the IgG Fc domain, and play important roles in modulating antibody effector functions and other biological processes. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch41/#:~:text=Glycans%20are%20critical%20components%20of,underlying%20endothelial%20cells'] bGSL:baf86c36-6899-4317-bdd6-68795f8695fe sialylated O-GalNAc glycan sialylated O-glycan sialyl T antigen O-GalNAc-linked sialoglycans 2B EOG_VARKI_4E O-linked glycans that are initiated by N-acetylgalactosamine (GalNAc) and further modified by the addition of sialic acid residues, typically through the action of α2-3 sialyltransferases such as ST3GAL1. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch10/#:~:text=A%20family%20of%20%CE%B12-6,Gal%20residue%20of%20core%201%20O-glycans'] bGSL:f46367fc-9181-45b4-a5ec-016a1c971f38 sialylated O-glycan sialylated O-GalNAc glycan; O-GalNAc-linked sialoglycans O-linked sialoglycan 2B EOG_VARKI_4E Sialylated O-glycans are O-linked glycans that possess terminal sialic acid residues. These structures can be biosynthesized in engineered yeast expressing human sialyltransferases. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch56/#:~:text=Examples%20of%20this%20include%20the%20hinge,O-glycan%20engineering%20in%20yeast'] bGSL:3f848a44-e85e-44a1-884d-1601181f9b2b sulfated glycan sulfated glucuronosyl glycan; sulfated galactan; sulfated N-glycan 2B EOG_VARKI_4E Sulfated glycans are glycans that contain sulfate groups. This category includes a variety of structures, such as those recognized by L-selectin, the HNK-1 epitope, and pituitary glycoprotein hormones. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch14/#:~:text=However%2C%20in%20vertebrates%2C%20glycan,is%20remarkably%20rare%20in%20prokaryotes', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch31/#:~:text=The%20diversity%20of%20R-type%20lectin,domain%20binds%20to%20sulfated%20glycans'] bGSL:8e1f097b-dfcc-4de0-8e28-a114ebe12e51 sulfated glycosaminoglycan sulfated glycosaminoglycan chains sulfated GAG glycosaminoglycans O-xylose-linked glycosaminoglycan 2B EOG_VARKI_4E Sulfated glycosaminoglycans (GAGs) are a class of linear polysaccharides that include heparan sulfate, chondroitin sulfate, dermatan sulfate, and keratan sulfate. These molecules are characterized by the presence of sulfate groups and are typically covalently attached to core proteins in proteoglycans. They play important roles in cell signaling, extracellular matrix structure, and protein interactions. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch30/#:~:text=As%20with%20many%20complexes%20involving%20a,that%20make%20contact%20with%20a%20protein', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch40/#:~:text=These%20glycans%20may%20facilitate,patterns%20specific%20to%20the%20pathogens', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch07/#:~:text=The%20challenge%20then%20is%20to%20predict,to%20have%20reinvented%20%28Chapter%2017%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch28/#:~:text=GBPs%20%28which%20exclude,are%20evolutionarily%20unrelated', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch28/#:~:text=The%20influenza%20virus%20hemagglutinin%2C,as%20antithrombin%20in%20the%201950s', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch28/#:~:text=Many%20other%20sulfated%20GAG-binding,molecules%2C%20cells%2C%20and%20information', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch28/#:~:text=Lectins%20in%20multicellular%20organisms,cells%20of%20the%20urinary%20tract', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch40/#:~:text=Hyaluronan%20oligosaccharides%20bind,receptor%20or%20activation%20of%20a%20kinase', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch40/#:~:text=Indeed%2C%20few%20membrane%20receptors,depots%20in%20the%20extracellular%20matrix', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch51/#:~:text=Different%20approaches%20and,%28LC%29%20and/or%20mass%20spectrometry%20%28MS%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch01/#:~:text=Numerous%20natural%20bioactive,to%20grow%20at%20an%20increasing%20rate', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch17/#:~:text=In%20fact%2C%20many%20proteoglycans%20show,discussed%20further%20in%20Chapter%2038', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch16/#:~:text=Melanie%20Simpson%2C%20Liliana%20Schaefer%2C,followed%20in%20the%20early%201930s', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch08/#:~:text=The%20fact%20that%20genetic%20variations,%28CRDs%29%20have%20been%20found%20useful', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch16/#:~:text=The%20gene%20shows%20homology%20with%20a,occurs%20at%20their%20nonreducing%20ends', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch17/#:~:text=These%20interactions%20have%20profound,found%20on%20many%20other%20glycoproteins', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch37/#:~:text=As%20such%2C%20these%20toxins%20function%20by,on%20the%20surface%20of%20host%20cells', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch40/#:~:text=Sugars%20%28glucose%2C%20fructose%2C%20and,%28Chapters%2017%20and%2038%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch40/#:~:text=These%20glycans%20may%20facilitate,patterns%20specific%20to%20the%20pathogens', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch55/#:~:text=Care%20must%20be%20taken%20in%20interpreting,one%20step%20from%20UDP-GlcA%20%28Chapter%205%29'] bGSL:731d7682-c96e-4739-9178-51368e7d1092 sulfated N-glycan sulfated glycan 2B EOG_VARKI_4E N-glycans that are modified by the addition of sulfate groups, as seen in structures present on pituitary gonadotropin hormones and in keratan sulfate. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch07/#:~:text=It%20is%20possible%20to%20search%20for%20such,of%20the%20hormones%20%28Chapter%2031%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch14/#:~:text=However%2C%20in%20vertebrates%2C%20glycan,is%20remarkably%20rare%20in%20prokaryotes'] bGSL:00dd715d-ad12-4d78-993b-629c424dc46a sulfated O-GalNAc glycan sulfated mucin-type glycan 2B EOG_VARKI_4E O-glycans of the mucin type that are modified by sulfation, and have been detected in species such as Drosophila and mosquito. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch26/#:~:text=In%20Drosophila%20and%20mosquito%2C,in%20super%20sex%20combs%20%28sxc%29%20mutants'] bGSL:11ec5550-83b8-4200-8d7b-74aca77ff5bc sulfated terminal β-linked GalNAc terminal N-acetylgalactosamine; terminal β-linked N-acetylgalactosamine 2B EOG_VARKI_4E Terminal N-acetylgalactosamine (GalNAc) residues that are β-linked and sulfated. These motifs are found on pituitary glycoprotein hormones such as lutropin (LH) and thyrotropin (TSH), where they play a role in the structure and function of these glycoproteins. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch14/#:~:text=The%20Forssman%20antigen%2C%20first,it%20is%20made%20in%20the%20same%20cells', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch14/#:~:text=Consequently%2C%20the%20biantennary,of%20the%20hormone%20by%20the%20pituitary'] bGSL:cb1f554e-a65c-4706-bb52-f70ac9af6c79 truncated N-glycan trimannosyl core 2B EOG_VARKI_4E Truncated N-glycans are N-linked glycans that are incompletely processed, often due to prolonged retention in the endoplasmic reticulum, resulting in shorter glycan chains than typically found in mature N-glycans. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch39/#:~:text=How%20do%20cells%20distinguish%20between,thought%20to%20be%20devoid%20of%20activity'] bGSL:a88cfa30-3266-47e6-adad-b12b3ad00721 truncated O-GalNAc glycan truncated O-glycan truncated core 1 O-glycan 2B EOG_VARKI_4E O-glycans initiated by GalNAc on serine or threonine residues that are incompletely extended, including structures such as Tn, STn, and T antigens, which are often associated with cancer. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch47/#:~:text=In%20addition%2C%20the%20core-fucosylated,residual%20disease%20after%20surgery'] bGSL:53f157f7-cfa3-4eaf-b6a6-7a746cfb6145 truncated O-glycan incomplete O-glycan truncated O-GalNAc glycan; truncated core 1 O-glycan 2B EOG_VARKI_4E Truncated O-glycans are O-linked glycans that are not fully elongated or processed, often terminating in early core structures such as Tn antigen, T antigen, or their sialylated forms (STn, ST). These incompletely extended glycans frequently expose core structures and are commonly observed in carcinomas, where they can evoke immune responses. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch47/#:~:text=Mucins%20might%20also%20interfere%20with,receptor%20%28CAR%29%20T-cell%20therapies'] ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch47/#:~:text=Mucins%20might%20also%20interfere%20with,receptor%20%28CAR%29%20T-cell%20therapies'] bGSL:eb08c74d-ada3-40c8-a476-d55b39394b79 xylosylated glycans O-xylose-linked glycosaminoglycan 2B EOG_VARKI_4E Xylosylated glycans are glycans that contain xylose residues. These glycans may be attached to glycoproteins or glycolipids and are found in various organisms, including parasites. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch43/#:~:text=The%20LeX%20antigen%2C%20which%20is%20abundant,and%20adaptive%20immune%20responses'] bGSL:af078ac6-c49d-4dfe-ab94-79cab0339bbb α-linked mannose Mannose terminal α-linked mannose; terminal α1-6 mannose 2B EOG_VARKI_4E A mannose residue attached through an alpha glycosidic bond, frequently found in diverse glycan structures and recognized by mannose-binding proteins. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch13/#:~:text=Moreover%2C%20loss%20of%20C-mannosylation,Tadashi%20Suzuki%2C%20and%20Jon%20Agirre', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch29/#:~:text=Some%20researchers%20use%20the%20term,or%20multivalent%20glycan%20ligands'] bGSL:04053670-9434-462d-b374-ff3aaf9f4acb α-mannose-containing glycan O-mannose glycan; α-mannan; 2,6-branched O-mannose 2B EOG_VARKI_4E A glycan structure that contains at least one α-linked mannose residue, which is recognized as a pathogen-associated molecular pattern (PAMP) by immune receptors. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch34/#:~:text=Mice%20have%20the%20Ly49%20family%20of,immune%20responses%20against%20infection'] bGSL:041e17c1-003e-4b0b-ba63-1efc71363cf6 asialylated biantennary N-glycan asialo diantennary biantennary N-glycan; desialylated glycan; fucosylated asialo-biantennary N-glycan; nonsialylated N-glycan 2C GSD:00013 GSD_GLYGEN_V1 Typical crystallizable fragment (Fc) glycans attached to the CH2 domain in therapeutic monoclonal antibodies (mAbs) are core-fucosylated and asialo-biantennary complex-type glycans, e.g., G2F (full galactosylation), G1aF (terminal galactosylation on the Man α1-6 arm), G1bF (terminal galactosylation on the Man α1-3 arm), and G0F (non-galactosylation).[PMID:30990348] bGSL:058b3e30-936f-45f1-b526-b6b6f0546f61 biantennary complex-type N-glycan diantennary complex type biantennary N-glycan; complex-type N-glycan; complex glycan sialylated complex-type N-glycan 2C GSD:00017 GSD_GLYGEN_V1; EOG_VARKI_4E A complex N-glycan that has two branches attached to the non-reducing terminal Man residues of the trimannosyl core. . Each branch is initiated with a GlcNAc and can be exteneded or capped with HexNAc, deoxyHex, Hex, or sialic acid residues. [CHEBI:156251] The crystal structure of Pterocarpus angolensis lectin is determined in its ligand-free state, in complex with the fucosylated biantennary complex type decasaccharide NA2F, and in complex with a series of smaller oligosaccharide constituents of NA2F.[PMID:16704415] bGSL:864fd21d-e8a0-449b-9d96-ffcb61830472 bisected complex-type N-glycan complex glycan; N-glycan core, bisected 2C EOG_VARKI_4E A complex-type N-glycan structure that contains a bisecting N-acetylglucosamine (GlcNAc) residue attached via β1-4 linkage to the core mannose of N-glycans. This modification is typically introduced by the enzyme MGAT3. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch48/#:~:text=L-PHA%20binding%20is%20dramatically,samples%20differ%20in%20glycosylation'] bGSL:64da93a5-2b96-4d11-8fa9-db7ca7a7ce96 core-fucosylated biantennary complex-type N-glycan core fucosylated diantennary complex-type core-fucosylated biantennary N-glycan; fucosylated biantennary N-glycan; core-fucosylated glycan 2C G78059CC GSD:00039 GSD_GLYGEN_V1 A biantennary complex glycan with two GlcNAc branches linked to the core and fucosylation on the core GlcNAc. The oligosaccharide structure at Asn(32 ) is a mixture of the monosialo and asialo forms of a core fucosylated biantennary complex-type oligosaccharide.[PMID:10731668] bGSL:4c5d3598-909f-40f1-afd3-3cc602a03f44 core-fucosylated biantennary N-glycan core-fucosylated diantennary biantennary N-glycan; fucosylated biantennary N-glycan; core-fucosylated glycan core-fucosylated biantennary complex-type N-glycan 2C G78059CC GSD:00038 GSD_GLYGEN_V1 A biantennary glycan with two GlcNAc branches linked to the core and fucosylation on the core GlcNAc. The IFN-alpha14c N-glycans were shown to exhibit core-fucosylated biantennary glycans , with about 10% carrying an additional alpha1,3-linked fucose unit at the antennae.[PMID:9654101] bGSL:20f7b02f-95be-4d51-ae2b-0b0c240c2959 difucosylated tetraantennary N-glycan fucosylated tetraantennary N-glycan; fucosylated N-glycan 2C GSD:00043 GSD_GLYGEN_V1 The tetra-antennary N-linked glycans that have four GlcNAc branches linked to the core and two fucose added. While fucosylated N-glycans derived from serum haptoglobin of patients with CP slightly increased, di-fucosylated tetra-antennary N-glycans were observed only at this site in PC patients, and were absent in the haptoglobin of normal controls and individuals with CP.[PMID:18214858] bGSL:bf54fe2a-d9b5-46ae-95ea-4e7922c4581c diphosphorylated Man6 Diphosphorylated Man_6 2C G54792LL; G10907PF GSD:00045 GlycoMotif:GGM.000054 GSD_GLYGEN_V1; CUMMINGS; GLYCOMOTIF_GGM Here we report that the single-chain variable domain (scFv) M6P-1 is a unique antibody fragment with specificity for Man6P monosaccharide that, through an array-screening approach against a number of phosphorylated N-glycans, is shown to bind mono- and diphosphorylated Man6 and Man7 glycans that contain terminal αMan6P(1 → 2)αMan(1 → 3)αMan.[PMID:26503547] bGSL:691c0532-c247-4d1a-83e9-eb0397d52231 disialylated biantennary complex-type N-glycan disialylated biantennary N-glycan; complex glycan; Disialyl-branched Type 2 2C GSD:00173 GSD_GLYGEN_V1 A biantennary complex glycan with two GlcNAc branches linked to the core and the addition of two sialic acid residues. The glycan was shown to be a disialylated biantennary complex type oligosaccharide N-linked to 318 Asn.[PMID:11738084] bGSL:14a332e7-7a89-4efc-94c1-caf74dca99c0 disialylated biantennary N-glycan sialylated biantennary N-glycan; biantennary N-glycan; Disialyl-branched Type 2 disialylated biantennary complex-type N-glycan 2C GSD:00169 GSD_GLYGEN_V1 A biantennary glycan with two GlcNAc branches linked to the core and the addition of two sialic acid residues. FAB-MS, electrospray-mass spectrometry, and linkage analysis demonstrated that each monomer of rat CRP contained one oligosaccharide chain , predominantly a disialylated biantennary structure , attached to Asn-128.[PMID:8486673] bGSL:7c961c4a-0e08-4262-883e-fe097b1be26c disialylated fucosylated glycan disialylated fucosylated disialyl-Lewis a; 2-fucosyl GD1b; fucosylated disialylated biantennary N-glycan 2C GSD:00049 GSD_GLYGEN_V1 A fucosylated glycan with two sialic acid components. Disialylated fucosylated and monosialylated non-fucosylated oligosaccharides were also identified.[PMID:17591618] bGSL:d37412e8-8847-42ca-be15-23b90d104127 fucosylated asialo-biantennary N-glycan fucosylated asialo-diantennary fucosylated biantennary N-glycan; fucosylated N-glycan; fucosylated glycan asialylated biantennary N-glycan 2C GSD:00052 GSD_GLYGEN_V1 Describing a biantennary oligosaccharide that has no sialic acid component but has fucose. We found that approximately 63% of the total N-linked oligosaccharides were of the complex type, with bisialo-biantennary (28%), asialo-biantennary (7%), fucosylated bisialo-biantennary (25%), and fucosylated asialo-biantennary (3%) oligosaccharides representing the major complex-type carbohydrate species.[PMID:2065054] bGSL:5c97aeae-fd84-4564-a4b7-1312a777c47c fucosylated biantennary N-glycan fucosylated N-glycan; fucosylated glycan fucosylated asialo-biantennary N-glycan; core-fucosylated biantennary N-glycan; core-fucosylated biantennary complex-type N-glycan; fucosylated disialylated biantennary N-glycan 2C GSD:00053 GSD_GLYGEN_V1 a biantennary glycan with two GlcNAc branches linked to the core and the addition of fucose. The profiles of the PSA N-glycans from the free and complexed molecules were quite similar to each other and consisted of fucosylated biantennary oligosaccharides as the major class.[PMID:17956937] bGSL:8c7cfb04-96e1-57b3-b09a-7c2a5fde12fa fucosylated disialylated biantennary N-glycan fucosylated disialo-biantennary fucosylated biantennary N-glycan; disialylated fucosylated glycan; fucosylated N-glycan; sialylated biantennary N-glycan; fucosylated glycan 2C GSD:00054 GSD_GLYGEN_V1 Describing a biantennary oligosaccharide that has two sialic acid component and fucose added. We found that approximately 63% of the total N-linked oligosaccharides were of the complex type, with bisialo-biantennary (28%), asialo-biantennary (7%), fucosylated bisialo-biantennary (25%), and fucosylated asialo-biantennary (3%) oligosaccharides representing the major complex-type carbohydrate species.[PMID:2065054] bGSL:3eb39082-59cb-494f-a49c-c94bc1cfd70d fucosylated tetraantennary N-glycan fucosylated N-glycan; tetraantennary N-glycan; fucosylated glycan difucosylated tetraantennary N-glycan 2C GSD:00051 GSD_GLYGEN_V1 A tetraantennary glycan with four GlcNAc branches linked to the core and the addition of fucose. The two major N-linked oligosaccharides of Namalwa EPO were fucose-containing tetraantennary and fucose-containing triantennary structures.[PMID:2550193] bGSL:b7ee1792-1875-4a98-ab62-1bb71fe9fe19 fucosylated triantennary N-glycan triantennary complex-type N-glycan; triantennary N-glycan; fucosylated glycan fucosylated trisialylated triantennary N-glycan 2C GSD:00057 GSD_GLYGEN_V1 A triantennary glycan with three GlcNAc branches linked to the core and the addition of fucose. Asn184 is only partially glycosylated and substituted by fucosylated triantennary and small amounts of diantennary N-acetyllactosaminic glycans.[PMID:2513186] bGSL:712e9e02-719d-49d2-8546-09955e14cd4b fucosylated trisialylated triantennary N-glycan fucosylated triantennary N-glycan; triantennary N-glycan; fucosylated N-glycan; trisialylated triantennary N-glycan; fucosylated glycan 2C GSD:00149 GSD_GLYGEN_V1 A triantennary glycan with three GlcNAc branches linked to the core and the addition of three sialic acid residues and fucose added. Diantennary monosialylated glycans and triantennary trisialylated fucosylated and non-fucosylated structures have also been identified.[PMID:17591618] bGSL:9f56c5d7-165d-47f1-8ebd-9d0751b215a0 galactose-terminated N-glycan branch terminal galactose 2-6-branch of complex N-glycans 2C EOG_VARKI_4E A branch of an N-glycan that ends with a galactose residue, typically in a β1-4 linkage to N-acetylglucosamine. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch30/#:~:text=Molecular%20docking%20can%20provide,site%20that%20contains%20the%20donor'] bGSL:ec3fe32b-ce59-43cd-84e9-f0672d9441e9 highly branched complex-type N-glycan highly branched complex-type N-glycans complex-type N-glycan; multiantennary complex-type N-glycan triantennary complex-type N-glycan 2C EOG_VARKI_4E A class of N-linked glycans characterized by multiple antennae (branches) that contain complex sugars. These highly branched structures are less likely to bind to ConA-agarose. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch29/#:~:text=Such%20an%20approach%20has%20been,N-glycans%20will%20not%20bind'] bGSL:f8221c6b-cdb9-4a3a-b651-fe2d8979a5cf monosialylated biantennary N-glycan monosialyl biantennary biantennary N-glycan; monosialylated N-glycan; sialylated biantennary N-glycan 2C GSD:00105 GSD_GLYGEN_V1 A biantennary glycan with two GlcNAc branches linked to the core and the addition of one sialic acid residues. In contrast, the sugar chain structure of HCC highly specific AFP isoform was found to comprise a monosialyl-biantennary sugar chain with additional fucosylation of the proximal N-acetylglucosamine.[PMID:7686446] bGSL:0cd33608-eed5-46d1-8689-2ee523c3bbf2 multiantennary complex-type N-glycan multiantennary complex-type complex-type N-glycan triantennary complex-type N-glycan; tetraantennary complex-type N-glycan; highly branched complex-type N-glycan 2C EOG_VARKI_4E Multiantennary complex-type N-glycans are N-glycans with a complex-type core structure that feature multiple antennae (branches) extending from the core mannose residues. These structures are characteristic of animal glycoproteins. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch20/#:~:text=In%20contrast%2C%20trimming%20to,expression%20of%20processing%20enzymes', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch56/#:~:text=This%20suggests%20that%20one%20must,N-glycans%20are%20targeted'] bGSL:a49273e3-083d-4df6-bc23-c5bb7ee2098e nonfucosylated biantennary N-glycan biantennary N-glycan 2C GSD:00115 GSD_GLYGEN_V1 A biantennary glycan with two GlcNAc branches linked to the core and no fucose appears. Structural analysis combining methylation-mass spectrometry and 400 MHz 1H-n.m.r. spectrometry of oligosaccharide alditols released from human leucocyte lactotransferrin shows the presence of two disialylated and non-fucosylated biantennary glycans of the N-acetyl-lactosaminic type.[PMID:2390069] bGSL:bd8348ad-41b3-4ea1-b8db-d8894ff07e96 O-GalNAc-linked sialoglycans O-glycans; O-linked sialoglycan; sialoglycan; sialylated O-glycan; mucin-type O-glycans sialylated O-GalNAc glycan 2C EOG_VARKI_4E O-GalNAc-linked sialoglycans are a type of O-GalNAc glycan that have been further modified by the addition of sialic acid residues. These structures are commonly found on mucins and other glycoproteins, where the sialic acid imparts extended and negatively charged properties to the glycan chains. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch15/#:~:text=These%20functions%20are%20not%20mutually,collapse%20without%20glycosylation'] bGSL:2fc9fdea-b5c4-4729-8299-ffedd446b536 O-linked sialoglycan sialoglycan O-GalNAc-linked sialoglycans sialylated O-glycan 2C EOG_VARKI_4E O-glycans that are terminated or modified with sialic acid residues, which can be recognized by carbohydrate recognition domains in certain proteins and play roles in cell attachment. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch46/#:~:text=Heparan%20sulfate%20%28HS%29%20found%20in%20the,attachment%20to%20cells%20in%20the%20mucosa'] bGSL:105b9d51-f41e-4105-8871-c58e990ae927 R-linked α-N-acetylglucosamine arginine-linked α-GlcNAc 2C EOG_VARKI_4E A glycopeptide motif in which N-acetylglucosamine (GlcNAc) is α-linked to the amino acid arginine. This structure is found in certain bacterial virulence factors. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch18/#:~:text=The%20recent%20discovery%20of%20a%20new,TRADD%2C%20FADD%2C%20RIPK1%2C%20and%20TNFR1'] bGSL:f8fa6ac5-76c3-4477-8955-ea0d5d2d3b17 sialofucosylated glycolipid sialylated glycolipid 2C EOG_VARKI_4E Glycolipids that are modified with both sialic acid and fucose residues, which are implicated in leukocyte adhesion and inflammatory responses. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch34/#:~:text=In%20this%20regard%2C%20whereas,and%20some%20memory/effector%20T%20cells'] bGSL:7f627b5e-e2d7-408d-9177-e2cfa4a77bc4 sialylated biantennary N-glycan sialyl biantennary biantennary N-glycan; sialoglycan monosialylated biantennary N-glycan; fucosylated disialylated biantennary N-glycan; disialylated biantennary N-glycan 2C GSD:00133 GSD_GLYGEN_V1; EOG_VARKI_4E A binantennary glycan with one or two sialic acid residues as non-reducing terminal residues on one or both antennae. [RN] Simbucus nigra agglutinin or an antibody specific to sialylated lactosamine with a preference for Neu5Acalpha2-6Gal rather than Neu5Acalpha2-3Gal reduced sperm binding to oviduct isthmic cells, as did occupying putative receptors on sperm with sialylated biantennary glycans.[PMID:23115267] bGSL:2e955e95-6126-442e-aba7-428b42d46e35 sialylated complex-type N-glycan sialo-complex type; complex sialylated N-glycan complex-type N-glycan; biantennary complex-type N-glycan; complex glycan; sialoglycan; sialylated N-glycan sialylated tetraantennary N-glycan 2C GSD:00134 GSD_GLYGEN_V1; EOG_VARKI_4E Complex N-linked glycan that have added GlcNAc residues at both the α-3 and α-6 mannose sites and do not contain mannose residues apart from the core structure but with sialic acid residues. By using 1H-NMR spectroscopy we were able to establish that our product contains a single N-linked biantennary , fully sialylated complex-type oligosaccharide , typical of human hepatomas.[PMID:1694115] bGSL:9a25db13-9d27-48a2-9b13-dacf9a0f9bf8 sialylated tetraantennary N-glycan sialylated complex-type N-glycan; tetraantennary N-glycan; tetraantennary complex-type N-glycan; sialylated N-glycan 2C GSD:00136 GSD_GLYGEN_V1 A tetraantennary glycan with four GlcNAc branches linked to the core and the addition of one sialic acid residues. A small amount of sialylated tetraantennary oligosaccharide was detected.[PMID:16321355] bGSL:681a3459-818f-403e-8238-924d38818763 sulfated glucuronosyl glycan sulfated glycan 2C EOG_VARKI_4E Glycans that contain sulfated glucuronic acid residues, such as those found in the HNK-1 epitope, which is recognized by specific monoclonal antibodies. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch46/#:~:text=In%20some%20studies%2C%20HS%20injections,%28the%20so-called%20HNK-1%20epitope%29'] bGSL:4be440a8-04b7-4940-91dd-64c0a6e71851 terminal fucose terminal Fuc residue fucose Fucα1-2Gal; Outer arm fucose; terminal α-linked fucose 2C EOG_VARKI_4E A glycan structure featuring a fucose residue at the non-reducing terminus of glycan chains, as found in H and Lewis antigens. These terminal fucose residues can be cleaved by fucosidases. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch14/#:~:text=They%20show%20robust%20titers%20of%20anti-H%2C,such%20as%20the%20H%20and%20Lewis%20antigens'] ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch42/#:~:text=When%20dietary%20fucose%20is%20low%2C%20the,are%20missing%20from%20the%20diet'] bGSL:83187390-2957-43b9-b5e8-6edd9e3ad006 terminal galactose terminal Gal residue galactose-terminated N-glycan branch; terminal α-linked-galactose; terminal β-linked galactose 2C EOG_VARKI_4E A galactose residue located at the non-reducing end of a glycan, often exposed after the removal of terminal sialic acids. This structural feature can influence glycan recognition and function. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch28/#:~:text=Like%20most%20glycoproteins,or%20GlcNAc%20residues%20from%20the%20blood', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch28/#:~:text=Once%20released%20from%20cells%2C,degradation%20of%20cellulose%20fibers', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch14/#:~:text=St3gal5%20is%20expressed%20well%20in,receptor%20%28Chapter%2034%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch47/#:~:text=In%20normal%20physiology%20platelets%2C,of%20SLex%20and%20SLea%20in%20cancers', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch37/#:~:text=Whereas%20these%20secondary,to%20manage%20E.%20histolytica%20infection'] bGSL:c4b3c0e9-b9fb-43c8-8721-e5adbb821a64 terminal glucuronic acid 2C EOG_VARKI_4E Glucuronic acid residues present at the non-reducing end of glycan chains, commonly observed in certain N-glycans. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch25/#:~:text=The%20cattle%20parasite%20D.%20viviparous,Examples%20of%20nematode%20glycans'] bGSL:744e491c-df18-4c2b-8a7b-f9298f976870 terminal mannose terminal Man mannose-terminated N-glycan; terminal α1-6 mannose; terminal α-linked mannose 2C EOG_VARKI_4E Mannose residues located at the non-reducing end of glycan chains, which are important for recognition by mannose receptors. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch44/#:~:text=The%20cost%20of%20treatment%20is%20high%2C%20and,is%20under%20development%20for%20others'] bGSL:3e71e3dc-2018-4dd0-a83c-93f84c0292ee terminal N-acetylgalactosamine terminal GalNAc residue N-acetylgalactosamine sulfated terminal β-linked GalNAc; terminal β-linked N-acetylgalactosamine 2C EOG_VARKI_4E N-acetylgalactosamine (GalNAc) residues located at the non-reducing end of glycan chains, commonly present on certain N-glycans and recognized by specific lectins and receptors. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch28/#:~:text=Once%20released%20from%20cells%2C,degradation%20of%20cellulose%20fibers', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch37/#:~:text=Whereas%20these%20secondary,to%20manage%20E.%20histolytica%20infection', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch14/#:~:text=Consequently%2C%20the%20biantennary,of%20the%20hormone%20by%20the%20pituitary'] bGSL:3aed1a1b-b8c2-4799-a5a4-dafb63b89de9 terminal N-acetylglucosamine terminal GlcNAc residue N-acetylglucosamine 2C EOG_VARKI_4E A glycan feature where N-acetylglucosamine (GlcNAc) is present at the nonreducing end of a glycan chain. This terminal GlcNAc can serve as an acceptor for galactosyltransferases and is recognized by certain lectins, playing a role in glycan recognition and modification. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch28/#:~:text=It%20is%20also%20noteworthy%20that%20viruses,evolved%20by%20convergent%20evolution', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch34/#:~:text=The%20purified%20rabbit%20AMR,the%20best%20characterized%20receptors', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch19/#:~:text=This%20seemingly%20simple%20carbohydrate,glycoconjugates%20%28Chapter%206%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch48/#:~:text=For%20example%2C%20the%20gene%20encoding%20a,glycans%20on%20their%20surface'] bGSL:f283ade4-77cd-41b4-bb36-805b56146dc4 terminal sialic acid Terminal Sia residue 2C EOG_VARKI_4E A glycan feature characterized by the presence of sialic acid (Sia) residues at the nonreducing end of a glycan chain. These terminal sialic acids can be removed by mild acid treatment or further modified, and their removal exposes the underlying sugar residues. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch10/#:~:text=O-GalNAc%20glycans%2C%20as%20well%20as%20other,O-GalNAc%20glycans%20on%20a%20glycoprotein', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch09/#:~:text=Many%20of%20these%20structures%20are,of%20GNPTAB%20and%20GNPTG%29%20%28Figure%209.4%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch28/#:~:text=Like%20most%20glycoproteins,or%20GlcNAc%20residues%20from%20the%20blood'] bGSL:9a8c9bf3-32b7-47ff-be1b-1edf66fe6ce8 terminal α-linked fucose terminal fucose; fucose Fucα1-2Gal; Outer arm fucose 2C EOG_VARKI_4E A glycan feature characterized by the presence of an α-linked fucose residue at the nonreducing end of a glycan chain. This structural motif is recognized by certain lectins and adhesion molecules, playing important roles in molecular recognition and cell signaling. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch34/#:~:text=Interestingly%2C%20different%20regions,%E2%80%9Cself-antigens%E2%80%9D%20from%20pathogens'] bGSL:28281013-6712-4f59-9d1f-3d1ba4ae0dd7 terminal α-linked mannose terminal mannose; α-linked mannose terminal α1-6 mannose 2C EOG_VARKI_4E A glycan feature where α-linked mannose is present at the nonreducing end of a glycan chain; this motif is recognized by certain lectins and adhesion molecules. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch34/#:~:text=Interestingly%2C%20different%20regions,%E2%80%9Cself-antigens%E2%80%9D%20from%20pathogens'] bGSL:601562b2-87b6-431e-b6c0-e866bfbce587 terminal α-linked-galactose terminal α-galactose residue terminal galactose 2C EOG_VARKI_4E A glycan feature characterized by the presence of α-linked galactose at the nonreducing end of a glycan chain. The occurrence or absence of terminal α-galactose can be used to distinguish glycan types among different species or cell lines. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch48/#:~:text=More%20details%20about%20glycosylation,with%20plates%20coated%20with%20the%20lectin'] bGSL:163bef7c-5e2f-48b3-bcff-1c7207ee5d52 terminal α1-6 mannose terminal α1–6Man terminal mannose; terminal α-linked mannose; α-linked mannose 2C EOG_VARKI_4E A glycan feature where a mannose residue is present at the nonreducing end of a glycan chain, linked via an α1-6 glycosidic bond. This terminal α1-6 mannose is important for recognition by specific endoplasmic reticulum lectins and plays a role in ER-associated degradation pathways. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch39/#:~:text=Retrotranslocation%20of%20misfolded,by%20Hrd3p%20in%20the%20Hrd1%20complex'] ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch39/#:~:text=Mammalian%20cells%20have%2C%20in%20addition,Yos9p%20in%20Saccharomyces%20cerevisiae%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch39/#:~:text=The%20M7BC%20isomer%20exposes%20an%20%CE%B11%E2%80%936Man,protein%20called%20Htm1p%20are%20present'] bGSL:e06ccfbc-ef4b-48f4-837b-a202fdf1439d terminal β-linked galactose terminal galactose; β-linked galactose 2C EOG_VARKI_4E A glycan feature characterized by the presence of β-linked galactose at the nonreducing end of a glycan chain. This terminal structure can serve as a substrate for sialylation or be recognized by specific lectins. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch43/#:~:text=These%20GPI-anchored%20proteins%20form%20a,these%20are%20far%20less%20well%20studied.%20T'] bGSL:d5f785f0-62e9-411a-8ab6-467c0c55b4f7 terminal β-linked N-acetylgalactosamine terminal N-acetylgalactosamine sulfated terminal β-linked GalNAc; β4-linked N-acetylgalactosamine 2C EOG_VARKI_4E A glycan feature characterized by the presence of N-acetylgalactosamine (GalNAc) at the nonreducing end of a glycan chain in a β-linkage. This terminal structure is recognized by specific lectins and receptors, including the asialoglycoprotein receptor and the AMR. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch28/#:~:text=Like%20most%20glycoproteins,or%20GlcNAc%20residues%20from%20the%20blood', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch34/#:~:text=The%20efficiency%20of%20the%20AMR%20in,normal%20without%20challenge'] bGSL:332b75fb-4386-47c6-8c73-b8f1e178876c tetraantennary complex-type N-glycan multiantennary complex-type N-glycan; tetraantennary N-glycan complex-type N-glycan; sialylated tetraantennary N-glycan 2C GSD:00145 GSD_GLYGEN_V1 Type of N-linked glycan in which four antennae are present on the trimannosyl core, each initiated by GlcNAc additions catalyzed by position-specific N-acetylglucosaminyltransferases (GlcNAcTs). The four antennae are initiated by addition of 2 GlcNAcs to the _3 Man (at the 2 and 4 positions) and 2 GlcNAcs to the _6 Man (at the 2 and 6 positions) of the trimannosyl core. Each antenna can be extended or capped with HexNAc, deoxyHex, Hex, or sialic acid residues. [Essentials of Glycobiology:Glossary] A variety of high-mannose structures , as well as bi-, tri-, and tetraantennary complex-type carbohydrate , has been found, in relative amounts of 1-25% of the total oligosaccharides.[PMID:1899031] bGSL:aae55cab-707b-4902-bd4e-2ea945a11d6f tetrasialylated biantennary N-glycan biantennary N-glycan 2C GSD:00170 GSD_GLYGEN_V1 A biantennary glycan with two GlcNAc branches linked to the core and the addition of four sialic acid residues. A further preparation, obtained from the most anionic DEAE-cellulose fraction (peak V) or rTf contained several tetrasialylated diantennary glycans whose precise structures remain to be established in future studies.[PMID:1997323] bGSL:74e4c965-b3af-4e2e-9e87-d1d4ac6513e4 triantennary complex-type N-glycan Triantennary complex-type triantennary N-glycan; complex glycan; highly branched complex-type N-glycan; multiantennary complex-type N-glycan nonfucosylated triantennary N-glycan; fucosylated triantennary N-glycan 2C GSD:00147 GSD_GLYGEN_V1 A complex N-glycan that has three branches attached to the non-reducing terminal Man residues of the trimannosyl core.[CHEBI:156252] Each branch is initiated with a GlcNAc and can be exteneded or capped with HexNAc, deoxyHex, Hex, or sialic acid residues. Fucosylated biantennary complex-type and small amounts (less than 5%) of triantennary complex-type structures were identified on the glycosylated asparagine residues using sequential exoglycosidase and endoglycosidase digestions combined with matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS).[PMID:9118998] bGSL:cb54c5df-a9d9-4b66-b5e0-fe06018b922d trisialylated biantennary N-glycan biantennary N-glycan 2C GSD:00153 GSD_GLYGEN_V1 A diantennary/biantennary glycans with three sialic acid components. Determination of glycan primary structures and characterization of a new type of trisialylated diantennary glycan.[PMID:1997323] bGSL:84aa2c7b-59cc-4171-a768-29c73b38f1ff trisialylated triantennary N-glycan triantennary N-glycan fucosylated trisialylated triantennary N-glycan; nonfucosylated triantennary N-glycan 2C GSD:00154 GSD_GLYGEN_V1 A triantennry glycan with three sialic acid components. The N-glycans are of the complex type with the core-fucosylated disialylated biantennary and trisialylated triantennary structures predominating.[PMID:8942648] bGSL:1d067417-3895-451a-8502-138616f96039 (Man)2-GlcNAc dimannosyl-N-acetylglucosamine 2D BIOOLIGO bGSL:24f4ee96-e978-4651-85b8-cf26c796483e (Man)3a Man a1-3 (Man a1-6) Man 2D BIOOLIGO bGSL:ce277368-07b5-45b4-a1bb-6a1fe2e1450f (Man)3b 2D BIOOLIGO bGSL:35738357-1170-4d3d-8a4c-79f69b2f982c (Man)4 2D BIOOLIGO bGSL:cb9fe384-844e-4d05-8e56-81c8cdd47b91 (Man)4-(Fuc)-GlcNAc 2D BIOOLIGO bGSL:239181b3-1414-5970-9cc1-9a096f2060a1 (Man)6 (GlcNAc)2 Man a1-2 Man a1-6 Man a1-6 (Man a1-2 Man a1-3) Man b1-4 GlcNAc b1-4 GlcNAc b Man6 2D BIOOLIGO bGSL:dfd4970a-369d-42f2-accb-4fcf7b97c3a2 (Man)9-GlcNAc-GlcNAc Man9 2D BIOOLIGO bGSL:68975605-aaf1-457a-bb49-df32ffb01846 A1 2D G61751GZ GLYGEN_CURATORS_NCOMPO afucosylated agalactosylated monantennary N-glycan bGSL:1cad453c-c13c-4eff-bcfd-71dc4c50dd82 A1G1 2D G69411IG GLYGEN_CURATORS_NCOMPO afucosylated monogalactosylated monantennary N-glycan bGSL:7bac59ea-61b4-4c37-86f7-d7e444bf4aea A2 A2B 2D G36191CD GLYGEN_CURATORS_NCOMPO afucosylated agalactosylated biantennary N-glycan bGSL:6bcc4ada-c333-43b8-920a-9b7fe76eec0b A2[3]G1 A2BG1; A2G1 2D G66937TJ GLYGEN_CURATORS_NCOMPO afucosylated 3-arm monogalactosylated biantennary N-glycan bGSL:34941879-8927-4b0e-84b1-1bd75f2536d3 A2[6]G1 A2BG1; A2G1 2D G89993FE GLYGEN_CURATORS_NCOMPO afucosylated 6-arm monogalactosylated biantennary N-glycan bGSL:7ef73ce7-68c6-4fea-ab71-33113ce04268 A2B A2 2D G59471TH GLYGEN_CURATORS_NCOMPO afucosylated bisected agalactosylated biantennary N-glycan bGSL:6691df5c-d51a-4df0-a67c-88d604f6cb7e A2BG1 A2[3]G1; A2[6]G1 2D G72718TT GLYGEN_CURATORS_NCOMPO afucosylated bisected monogalactosylated biantennary N-glycan bGSL:d20ed9b0-5b59-470d-bfde-5aad3adeba39 A2BG2 A2BG2S1; A2BG2S2 2D G52934AK GLYGEN_CURATORS_NCOMPO afucosylated bisected digalactosylated biantennary N-glycan bGSL:613ba69b-83da-4f4d-a5b2-556006bd7f5c A2BG2S1 A2BG2 2D GLYGEN_CURATORS_NCOMPO afucosylated bisected digalactosylated monosialylated biantennary N-glycan bGSL:3be70b53-eece-41ae-900b-b6309de04be5 A2BG2S2 A2BG2 2D GLYGEN_CURATORS_NCOMPO afucosylated bisected digalactosylated disialylated biantennary N-glycan bGSL:ce573884-c239-4b23-9835-83dd0a2fb7ad A2F1 2D GLYGEN_CURATORS_NCOMPO afucosylated mono-antennary-fucosylated agalactosylated biantennary N-glycan bGSL:b4bc456a-441b-4c51-885a-8048ccb9521f A2F1G2S2 2D GLYGEN_CURATORS_NCOMPO afucosylated mono-antennary-fucosylated digalactosylated disialylated biantennary N-glycan bGSL:e9a8e591-e50a-443b-b591-7500ce88eab8 A2G1 A2[3]G1; A2[6]G1 2D G66937TJ GLYGEN_CURATORS_NCOMPO afucosylated monogalactosylated biantennary N-glycan bGSL:e16007a5-1656-45f6-afd2-6606bc970d89 A2G2 2D G36191CD GLYGEN_CURATORS_NCOMPO afucosylated digalactosylated biantennary N-glycan bGSL:af0795c7-5811-4404-ac1e-bc7ed23b3e54 A2G2S1 2D GLYGEN_CURATORS_NCOMPO afucosylated digalactosylated monosialylated biantennary N-glycan bGSL:cfdcf316-ca89-49d5-9a16-ebde43336b9f A2G2S2 2D GLYGEN_CURATORS_NCOMPO afucosylated digalactosylated disialylated biantennary N-glycan bGSL:faf27821-9b97-438e-978a-14f54649e025 A3 2D G29011JC GLYGEN_CURATORS_NCOMPO afucosylated agalactosylated triantennary N-glycan bGSL:8ef6a66d-8962-475b-8f36-1a1539e5467a A3F1 2D GLYGEN_CURATORS_NCOMPO afucosylated mono-antennary-fucosylated agalactosylated triantennary N-glycan bGSL:a4a475f8-d35f-4c61-8a07-7ea652ba8b25 A3F1G3S2 2D GLYGEN_CURATORS_NCOMPO afucosylated mono-antennary-fucosylated trigalactosylated disialylated triantennary N-glycan bGSL:2a7de120-d3d4-4556-959a-fabdaf600d05 A3F1G3S3 2D GLYGEN_CURATORS_NCOMPO afucosylated mono-antennary-fucosylated trigalactosylated trisialylated triantennary N-glycan bGSL:4fd21663-6e8b-4614-964f-e555d8778b93 A3F2G3S3 2D GLYGEN_CURATORS_NCOMPO afucosylated di-antennary-fucosylated trigalactosylated trisialylated triantennary N-glycan bGSL:a32da6a5-c485-4f92-9f20-99806bb52eea A3G3 A3G3S3 2D G29857RC GLYGEN_CURATORS_NCOMPO afucosylated trigalactosylated triantennary N-glycan bGSL:983b8822-de69-4649-afcb-72e5994a45b7 A3G3S2 2D GLYGEN_CURATORS_NCOMPO afucosylated trigalactosylated disialylated triantennary N-glycan bGSL:529228fd-6ef3-4e89-841c-da1d97147a50 A3G3S3 A3G3 2D GLYGEN_CURATORS_NCOMPO afucosylated trigalactosylated trisialylated triantennary N-glycan bGSL:fe472abc-5d67-42a3-a0de-fbabdddb2b9e A4 2D G20030CU GLYGEN_CURATORS_NCOMPO afucosylated agalactosylated tetraantennary N-glycan bGSL:fd170bcb-8ed8-494a-bac1-159af4a61008 A4F1 2D GLYGEN_CURATORS_NCOMPO afucosylated mono-antennary-fucosylated agalactosylated tetraantennary N-glycan bGSL:c033beaa-9bd2-46be-a77f-d6e895d225e9 A4F1G4 2D GLYGEN_CURATORS_NCOMPO afucosylated mono-antennary-fucosylated tetragalactosylated tetraantennary N-glycan bGSL:34c9d0d0-9846-4e8e-ba11-ae87a1c4f4f4 A4F1G4S4 2D GLYGEN_CURATORS_NCOMPO afucosylated mono-antennary-fucosylated tetragalactosylated tetrasialylated tetraantennary N-glycan bGSL:d33430a8-fb1e-45f5-a241-19d1bb30b7ad A4G4 A4G4S2 2D G18938DW GLYGEN_CURATORS_NCOMPO afucosylated tetragalactosylated tetraantennary N-glycan bGSL:5030418e-57cd-4b3a-b8c5-6773f9ef3394 A4G4S1 2D GLYGEN_CURATORS_NCOMPO afucosylated tetragalactosylated monosialylated tetraantennary N-glycan bGSL:4d17061e-f462-47cb-bf87-f1dd7e0e547a A4G4S2 A4G4 2D GLYGEN_CURATORS_NCOMPO afucosylated tetragalactosylated disialylated tetraantennary N-glycan bGSL:f83c6339-e441-4b6f-8d31-8b10c900ca7a A4G4S3 2D GLYGEN_CURATORS_NCOMPO afucosylated tetragalactosylated trisialylated tetraantennary N-glycan bGSL:0012ae4c-3d62-41ad-8d67-145149cce2cc A4G4S4 2D GLYGEN_CURATORS_NCOMPO afucosylated tetragalactosylated tetrasialylated tetraantennary N-glycan bGSL:4ad465ec-322b-47f0-8c15-8e15641380a8 FA1 2D GLYGEN_CURATORS_NCOMPO core-fucosylated agalactosylated monantennary N-glycan bGSL:800e4e66-b809-49d9-9b30-948557bc0006 FA1G1 2D GLYGEN_CURATORS_NCOMPO core-fucosylated monogalactosylated monantennary N-glycan bGSL:5dff0f6f-5b2d-46b3-ac3e-011d2932ed21 FA2 FA2B 2D GLYGEN_CURATORS_NCOMPO core-fucosylated agalactosylated biantennary N-glycan bGSL:210b3e08-4a9f-4bfd-9310-b77f35c4128a FA2[3]BG1 2D GLYGEN_CURATORS_NCOMPO core-fucosylated bisected 3-arm monogalactosylated biantennary N-glycan bGSL:3081c71f-6a5f-4712-af18-b677432124ce FA2[3]G1 2D GLYGEN_CURATORS_NCOMPO core-fucosylated 3-arm monogalactosylated biantennary N-glycan bGSL:ea30d1d6-81f6-44ce-9cbc-bf42d6e4de9e FA2[3]G1S1 2D GLYGEN_CURATORS_NCOMPO core-fucosylated 3-arm monogalactosylated monosialylated biantennary N-glycan bGSL:93cbd50f-b106-4b86-8956-456dec571432 FA2[6]BG1 2D GLYGEN_CURATORS_NCOMPO core-fucosylated bisected 6-arm monogalactosylated biantennary N-glycan bGSL:2fc291b9-35fa-4c8f-b491-df7167cd95ae FA2[6]G1 2D GLYGEN_CURATORS_NCOMPO core-fucosylated 6-arm monogalactosylated biantennary N-glycan bGSL:d6fd8ac1-c709-428b-a429-59855acf0736 FA2B FA2 2D GLYGEN_CURATORS_NCOMPO core-fucosylated bisected agalactosylated biantennary N-glycan bGSL:a9d44f18-e905-46b5-8ba8-3beb64e88a0c FA2BG2 2D GLYGEN_CURATORS_NCOMPO core-fucosylated bisected digalactosylated biantennary N-glycan bGSL:97ec3c8f-84c8-457d-88f9-6297a546f88a FA2BG2S1 2D GLYGEN_CURATORS_NCOMPO core-fucosylated bisected digalactosylated monosialylated biantennary N-glycan bGSL:7dcdef24-21fe-4c13-a94d-0298a809f4e6 FA2BG2S2 2D GLYGEN_CURATORS_NCOMPO core-fucosylated bisected digalactosylated disialylated biantennary N-glycan bGSL:171716db-fe34-49d2-8289-2590683f6e9d FA2F1G2S2 2D GLYGEN_CURATORS_NCOMPO core-fucosylated mono-antennary-fucosylated digalactosylated disialylated biantennary N-glycan bGSL:05923149-e504-461c-9121-596419dc668a FA2G1 2D GLYGEN_CURATORS_NCOMPO core-fucosylated monogalactosylated biantennary N-glycan bGSL:253e3ade-9017-402c-bd6b-de2cae03ddb3 FA2G1S1 2D GLYGEN_CURATORS_NCOMPO core-fucosylated monogalactosylated monosialylated biantennary N-glycan bGSL:144d1008-f367-48ce-87e5-0f59e1950ea4 FA2G2 2D GLYGEN_CURATORS_NCOMPO core-fucosylated digalactosylated biantennary N-glycan bGSL:ecbc49f6-c9e7-421a-842c-b0306979751b FA2G2S1 2D GLYGEN_CURATORS_NCOMPO core-fucosylated digalactosylated monosialylated biantennary N-glycan bGSL:a5fd3eba-3ee8-435b-a80e-9e314ae80c84 FA2G2S2 G2F 2D GLYGEN_CURATORS_NCOMPO core-fucosylated digalactosylated disialylated biantennary N-glycan bGSL:4b93c6d8-6392-4b2b-933b-93b875665b5a FA3 FA3B 2D GLYGEN_CURATORS_NCOMPO core-fucosylated agalactosylated triantennary N-glycan bGSL:5b2c1206-8ad5-4673-a047-6b2f2ea49d58 FA3B FA3 2D GLYGEN_CURATORS_NCOMPO core-fucosylated bisected agalactosylated triantennary N-glycan bGSL:ac91b90d-04d2-46e5-a394-3c9f64dc1d56 FA3F1G3S3 FA3G3 2D GLYGEN_CURATORS_NCOMPO core-fucosylated mono-antennary-fucosylated trigalactosylated trisialylated triantennary N-glycan bGSL:5715e5eb-1d69-43a3-84df-f16f00e8bb63 FA3G3 FA3F1G3S3 2D GLYGEN_CURATORS_NCOMPO core-fucosylated trigalactosylated triantennary N-glycan bGSL:f5d12862-3579-4ded-96ce-c39dda593116 FA3G3S3 2D GLYGEN_CURATORS_NCOMPO core-fucosylated trigalactosylated trisialylated triantennary N-glycan bGSL:e00305bb-85fe-4dec-8fe3-b1782e53d2b5 FA4 2D GLYGEN_CURATORS_NCOMPO core-fucosylated agalactosylated tetraantennary N-glycan bGSL:0d189fba-0ee4-4b66-931e-10fdc5874c5e FA4F1G4S4 2D GLYGEN_CURATORS_NCOMPO core-fucosylated mono-antennary-fucosylated tetragalactosylated tetrasialylated tetraantennary N-glycan bGSL:2d51e797-6377-46a5-b417-cda08b1a2d83 FA4G4 2D GLYGEN_CURATORS_NCOMPO core-fucosylated tetragalactosylated tetraantennary N-glycan bGSL:2d94b307-f191-4a93-b3d3-aed2a711a25f FA4G4S4 2D GLYGEN_CURATORS_NCOMPO core-fucosylated tetragalactosylated tetrasialylated tetraantennary N-glycan bGSL:e828e1e8-fc7e-41a0-95f7-c9268015288b G0 G0B; G0F; G0FB 2D G36191CD EOG_VARKI_4E; GLYGEN_CURATORS_NCOMPO A complex-type N-glycan that lacks galactose residues on its antennae (agalactosylated), typically featuring a core Man3GlcNAc2 structure with two terminal GlcNAc residues. This structure is commonly found on glycoproteins and is recognized by mannose-binding proteins. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch46/#:~:text=Other%20structural%20features%20are%20also,interactions%20with%20Fc%20receptors'] bGSL:c083f269-3511-4e2f-8bd4-e16310bedc88 G0-N 2D G61751GZ GLYGEN_CURATORS_NCOMPO afucosylated agalactosylated monoantennary N-glycan bGSL:f3d5e0ce-2247-4c10-b3c2-403934929bd2 G0B G0 2D G59471TH GLYGEN_CURATORS_NCOMPO afucosylated bisected agalactosylated biantennary N-glycan bGSL:90e17627-b68e-4b0d-b2c2-022e2b38a1af G0F G0 G0FB 2D GLYGEN_CURATORS_NCOMPO core-fucosylated agalactosylated biantennary N-glycan bGSL:bcd80674-6f96-446e-8266-16c179d077d2 G0FB G0F; G0 2D GLYGEN_CURATORS_NCOMPO core-fucosylated bisected agalactosylated biantennary N-glycan bGSL:296bfa78-8928-4de9-8199-ac7c84aeec75 G1 2D G66937TJ GLYGEN_CURATORS_NCOMPO afucosylated monogalactosylated biantennary N-glycan bGSL:ded39219-58fa-4181-abaa-e2370885daf4 G1F 2D GLYGEN_CURATORS_NCOMPO core-fucosylated monogalactosylated biantennary N-glycan bGSL:bb7fc1f7-efce-448f-8978-d9f4657b821b G1M9 2D GLYGEN_CURATORS_NCOMPO afucosylated high-mannose (9) N-glycan, terminal GlcNAc bGSL:3e307567-7074-4051-b68b-922f3c8094d3 G2 2D G36191CD GLYGEN_CURATORS_NCOMPO afucosylated digalactosylated biantennary N-glycan bGSL:08f4ce68-927d-44f9-9ed6-8ebef24a8bc7 G2F FA2G2S2 2D GLYGEN_CURATORS_NCOMPO core-fucosylated digalactosylated biantennary N-glycan bGSL:67db4b81-61e4-41e2-926c-c5a41fea3ec9 G2FS1 2D GLYGEN_CURATORS_NCOMPO core-fucosylated digalactosylated monosialylated biantennary N-glycan bGSL:31652c88-e6b2-44c6-b05c-49df1619a0d2 G2M9 2D GLYGEN_CURATORS_NCOMPO afucosylated high-mannose (9) N-glycan, terminal GlcNAc-GlcNAc bGSL:b964b320-5298-472a-845a-13bb212559e0 G9-B 2D G08855PJ SUGARBIND bGSL:5b1bf8ff-40f4-497d-826a-662861e01866 M3FX 2D G26295XE; G47379VH GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:2d72de06-ef1b-4fa2-af9b-6fac927969e7 M5 2D G32104JU GLYGEN_CURATORS_NCOMPO afucosylated high-mannose (5) N-glycan bGSL:aa3ed41b-cc42-4386-b356-543e5697f3a9 M6 2D G56038AR GLYGEN_CURATORS_NCOMPO afucosylated high-mannose (6) N-glycan bGSL:801b9699-e953-433f-a2ae-968ba02ba6ed M7AB 2D GLYGEN_CURATORS_NCOMPO afucosylated high-mannose (7) N-glycan, non-mannosylated branch A and C bGSL:03bab5ba-66b8-4c87-bac4-17c77f49de2f M7AC 2D GLYGEN_CURATORS_NCOMPO afucosylated high-mannose (7) N-glycan, non-mannosylated branch A and B bGSL:cd57d070-f745-4e07-8c2f-968887886cb8 M7BC Man7GlcNAc2 isomer BC Man7 2D EOG_VARKI_4E; GLYGEN_CURATORS_NCOMPO M7BC is a specific isomer of the Man7 (M7) high-mannose N-glycan. It is characterized by the absence of residues i and k compared to M8B, resulting in the exposure of an α1–6-linked mannose (residue j). M7BC is generated from M8B through the enzymatic action of EDEM1 and EDEM3. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch39/#:~:text=Mammalian%20cells%20have%2C%20in%20addition,Yos9p%20in%20Saccharomyces%20cerevisiae%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch39/#:~:text=The%20M7BC%20isomer%20exposes%20an%20%CE%B11%E2%80%936Man,protein%20called%20Htm1p%20are%20present'] bGSL:1a24bae5-7e0e-4674-a4af-f3216e96ced5 M8 M8A; M8C; M8B 2D G91704UR GLYGEN_CURATORS_NCOMPO afucosylated high-mannose (8) N-glycan bGSL:2f3ee8bf-ee5d-404f-99db-5a165d43398b M8A M8 2D GLYGEN_CURATORS_NCOMPO afucosylated high-mannose (8) N-glycan, non-mannosylated branch A bGSL:062e7f56-ddca-4eea-be1b-f1abc5a7f232 M8B Man8GlcNAc2 isomer B M8 2D EOG_VARKI_4E; GLYGEN_CURATORS_NCOMPO M8B is a specific isomer of the Man8 (M8) high-mannose N-glycan. It is generated from Man9 (M9) through demannosylation, a process mainly catalyzed by the enzyme EDEM2 in the endoplasmic reticulum. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch39/#:~:text=Mammalian%20cells%20have%2C%20in%20addition,Yos9p%20in%20Saccharomyces%20cerevisiae%29'] bGSL:563eb99c-d2a4-4b80-ab08-986bbdf2f98e M8C M8 2D GLYGEN_CURATORS_NCOMPO afucosylated high-mannose (8) N-glycan, non-mannosylated branch C bGSL:b406b288-a0bf-4d0e-8faf-4e1d973bb3e8 Man3 trimannosyl core; chitobiose 2D G22768VO EOG_VARKI_4E; BIOOLIGO; GLYGEN_CURATORS_NCOMPO A core N-glycan structure composed of three mannose and two N-acetylglucosamine residues, representing the minimal N-glycan core found in eukaryotes. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch56/#:~:text=PglBs%20from%20other%20species%2C%20or,of%20eukaryotic%20enzymes%20%28Table%2056.1%29'] bGSL:cd3e1663-a689-4f1b-8e64-59d0b4dcf0b8 Man5 2D G32104JU EOG_VARKI_4E; BIOOLIGO; GLYGEN_CURATORS_NCOMPO An N-glycan core structure consisting of five mannose and two N-acetylglucosamine residues, commonly found on glycoproteins and not associated with targeting them for degradation. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch39/#:~:text=In%20yeast%2C%20only%20an%20ER%20%CE%B1-mannosidase,it%20for%20degradation%20%28see%20below%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch43/#:~:text=These%20GPI-anchored%20proteins%20form%20a,these%20are%20far%20less%20well%20studied.%20T'] bGSL:1a099168-37c4-40b7-9075-be1e0aa3c335 Man6 (Man)6 (GlcNAc)2 2D G56038AR EOG_VARKI_4E; BIOOLIGO; GLYGEN_CURATORS_NCOMPO An N-glycan core structure composed of six mannose and two N-acetylglucosamine residues, commonly found as an intermediate in the biosynthesis of N-linked glycans. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch39/#:~:text=In%20yeast%2C%20only%20an%20ER%20%CE%B1-mannosidase,it%20for%20degradation%20%28see%20below%29'] bGSL:46a1d700-17fa-404f-a148-a030c08565e3 Man7 M7BC 2D G04216GB EOG_VARKI_4E; BIOOLIGO; GLYGEN_CURATORS_NCOMPO Man7 (Man7GlcNAc2) is an N-glycan core structure composed of seven mannose and two N-acetylglucosamine residues. It represents a high-mannose intermediate in the biosynthesis of N-glycans. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch55/#:~:text=Consumption%20of%20these%20plants%20by,vs.%20%CE%B1-mannosidase%29%20does%20not%20exist'] bGSL:91b6194a-2572-4d37-a84a-a61e595e1fe2 Man8 2D G91704UR EOG_VARKI_4E; GLYGEN_CURATORS_NCOMPO Man8 (Man8GlcNAc2) is an N-glycan core structure composed of eight mannose and two N-acetylglucosamine residues. It represents a high-mannose intermediate in the biosynthesis of N-glycans. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch55/#:~:text=Consumption%20of%20these%20plants%20by,vs.%20%CE%B1-mannosidase%29%20does%20not%20exist'] bGSL:15e72838-c699-4a2e-9303-1699a266f781 Man9 Man9GlcNAc2 (Man)9-GlcNAc-GlcNAc 2D G26508HK EOG_VARKI_4E; GLYGEN_CURATORS_NCOMPO Man9 (Man9GlcNAc2) is an N-glycan core structure composed of nine mannose and two N-acetylglucosamine residues. It represents a high-mannose intermediate in the biosynthesis of N-glycans. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch55/#:~:text=Consumption%20of%20these%20plants%20by,vs.%20%CE%B1-mannosidase%29%20does%20not%20exist'] bGSL:2d1be3e8-eec8-49c3-bcfb-dd9e1e1cdb7c N-Man5 GlcNAc 1-4 2D BIOOLIGO bGSL:3acb24e7-fa1c-4e3f-9055-73131274ff25 NA2F 2D G00998NI SUGARBIND bGSL:43f3c420-d81f-484c-8bfb-00d741d7bdad Glc3Man9GlcNAc2 2E EOG_VARKI_4E Glc3Man9GlcNAc2 is a fully assembled N-glycan precursor oligosaccharide consisting of three glucose, nine mannose, and two N-acetylglucosamine residues. It is transferred en bloc to nascent proteins, covalently linked to asparagine, during N-glycosylation in eukaryotes, representing the initial glycan attached to glycoproteins before further processing in the endoplasmic reticulum and Golgi apparatus. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch09/#:~:text=This%2014-sugar%20glycan%20is,in%20the%20process%20%28Figure%209.3%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch55/#:~:text=Plant%20alkaloids%20block%20N-linked,I%20and%20II%2C%20australine%20%28also%20from%20C'] ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch06/#:~:text=In%20this%20case%2C%20the%20nascent,diverse%20processes%20that%20it%20mediates', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch09/#:~:text=Following%20the%20covalent%20attachment,or%20deoxynojirimycin%20%28Chapter%2055%29'] bGSL:0f5727cc-f298-4279-8baa-1a58fed68e4a a-series gangliosides ganglioside; ganglio-series glycosphingolipid 3A EOG_VARKI_4E a-series gangliosides are a class of glycosphingolipids characterized by the presence of a single sialic acid residue attached to the inner galactose of the lactosylceramide core. They are biosynthesized through the addition of sialic acid to GM3 and cannot be directly converted to b-series gangliosides by sialyltransferases. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch11/#:~:text=Each%20branch%20is%20a%20committed,by%20a%20single%20galactosyltransferase'] bGSL:3da44ce6-6054-4b2c-9284-46f9c4124838 ABO blood group antigens 3A EOG_VARKI_4E ABO blood group antigens are terminal glycan structures found on glycoproteins and glycolipids that define the A, B, and H blood group types. These glycans serve as receptors for certain viruses and are specifically recognized by lectins and antibodies, playing a key role in blood group determination and immune recognition. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch20/#:~:text=Free%20glycans%20%28e.g.%2C%20milk,that%20use%20ABO%20glycans%20as%20receptors', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch36/#:~:text=Thus%2C%20other%20sugar%20units%20linked%20to,diversity%20of%20recognition'] bGSL:7e3f948c-96fd-4707-a11f-006af3dd5d96 arthro-series glycosphingolipid arthroseries; arthro-series; arthroseries glycolipids; arthroseries glycosphingolipids 3A G00014MO GlycoMotif:GGM.001103 EOG_VARKI_4E; GLYCOMOTIF_GGM; PUBDICT_GLYCAN_MOTIF; PUBDICT_MOTIF_GTC A family of glycosphingolipids (GSLs) characteristic of invertebrates, especially arthropods, built on a mactosylceramide core (Manβ1-4Glcβ-ceramide) that may contain multiple N-acetylglucosamine residues and is often further modified with galactose, fucose, glucuronic acid, phosphoethanolamine, or phosphorylcholine. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch11/#:~:text=In%20skin%2C%20it%20is%20a%20precursor%20of,in%20tissue-specific%20patterns', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch25/#:~:text=At%20least%20three%20major%20classes%20of,insect%20pests.%20Bt%20is%20toxic%20to%20C', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch25/#:~:text=dentatum%20%28Figure%2025.8%29.%20Examples,of%20mammalian%20innate%20immune%20systems', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch26/#:~:text=However%2C%20arthropods%20possess%20their,core%20%28Gal%CE%B21-4Glc%CE%B2-ceramide%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch26/#:~:text=The%20functional%20significance%20of,as%20modulators%20of%20cell%20fate', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch26/#:~:text=As%20in%20this%20human%20disorder%2C,of%20animal%20lectins%20%28Chapter%2028%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch26/#:~:text=Neutral%20arthroseries%20glycans%20are,diversity%20has%20also%20been%20identified'] bGSL:0650a12d-a52f-4f9f-b9bb-791e44c70d44 b-series gangliosides ganglioside; glycosphingolipids; ganglio-series glycosphingolipid Trisialogangliotetraosylceramide; GD1b 3A EOG_VARKI_4E b-series gangliosides are a class of glycosphingolipids characterized by the presence of two sialic acid residues attached to the inner galactose. Examples include GD3 and GT1b. These structures are formed through the action of sialyltransferases during glycosphingolipid biosynthesis. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch11/#:~:text=The%20biosynthesis%20of%20GSLs%20in%20the,of%20the%20%E2%80%9Cb-series%E2%80%9D%20gangliosides', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch35/#:~:text=Recombinant%20forms%20of%20MAG%20bind,which%20lack%20GT1b%20but%20express%20GD1a', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch35/#:~:text=Siglec-7%20is%20the%20major%20Siglec%20on,6-sulfo-SLex%20and%206%E2%80%B2-sulfo-SLex', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch11/#:~:text=Each%20branch%20is%20a%20committed,by%20a%20single%20galactosyltransferase', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch11/#:~:text=In%20contrast%2C%20tetanus%20and%20related,in%20glycolipid%20biosynthesis'] bGSL:d1c0f4ee-8173-401f-8b58-a3d76266ff80 blood group antigens 3A EOG_VARKI_4E A class of glycan epitopes found on glycoproteins and glycolipids that determine human blood groups, including the A, B, O(H), and other antigens. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch56/#:~:text=coli.%20LPS%20consists%20of%20a%20base%20lipid,production%20in%20bacteria'] bGSL:709a4faf-6960-4efa-ba89-7bb659d61811 c-series gangliosides c-series ganglioside; ganglio-series glycosphingolipid 3A EOG_VARKI_4E A class of gangliosides characterized by the presence of three sialic acid residues attached to the glycan core, including structures such as GT3 and its derivatives. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch11/#:~:text=Each%20branch%20is%20a%20committed,by%20a%20single%20galactosyltransferase'] bGSL:a4c14d8f-215f-42e4-9cb5-bbde2b33efc7 complex ganglioside ganglioside; ganglio-series glycosphingolipid 3A EOG_VARKI_4E Complex gangliosides are gangliosides with multiple glycan extensions beyond the simple monosialylated core, often containing additional sialic acid and N-acetylgalactosamine residues. They are synthesized by the sequential action of sialyltransferases and N-acetylgalactosaminyltransferases. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch45/#:~:text=The%20patients%E2%80%99%20plasma%20GSLs%20are,the%20progressive%20gait%20disorder'] bGSL:8fde8485-5a38-4900-a5fb-385c92877d51 complex glycan complex oligosaccharides sialylated complex-type N-glycan; complex-type N-glycan; triantennary complex-type N-glycan; biantennary complex-type N-glycan; bisected complex-type N-glycan; disialylated biantennary complex-type N-glycan 3A EOG_VARKI_4E Complex glycans are oligosaccharides with branched and extended structures, typically referring to mature N-glycans or O-glycans that have undergone extensive processing and addition of various sugars beyond the core. These structures often feature complex sugar chains, such as sialylated, sulfated, glucuronylated, or zwitterionic modifications, and include both complex N-glycans and other complex-type glycans. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch55/#:~:text=Consumption%20of%20these%20plants%20by,vs.%20%CE%B1-mannosidase%29%20does%20not%20exist'] ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch26/#:~:text=Although%20it%20was%20once%20thought%20that,in%20Drosophila%20and%20other%20insects', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch26/#:~:text=GlcNAcT-I%20catalyzes%20the%20first,have%20not%20been%20characterized'] bGSL:279887e9-5d16-4b42-a8ee-43ca7a043a23 complex glycolipid glycolipids 3A EOG_VARKI_4E Complex glycolipids are glycolipids that possess oligosaccharide chains longer or more branched than those found in simple mono- or disaccharide glycolipids. They are synthesized from precursors like glucosylceramide through additional glycosylation steps. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch55/#:~:text=Because%20cells%20take%20up,is%20missing%20%28Chapter%2044%29'] bGSL:08c9ec16-d1cf-4307-a12a-805d0f5f086c complex O-glycan O-glycans 3A EOG_VARKI_4E Complex O-glycans are O-glycans with extended and branched structures, typically formed by the sequential addition of monosaccharides to an initial N-acetylgalactosamine (GalNAc) linked to serine or threonine residues of proteins. These glycans are highly diverse and are commonly found on mucins and other glycoproteins. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch08/#:~:text=The%20baculovirus%20enzyme%20ecdysteroid,in%20their%20symbiosis%20and%20virulence'] bGSL:18bfbdbd-f6b7-46cb-8e45-96e927240321 gala-series glycosphingolipid Glycosphingolipid Gala series 3A G00016MO GlycoMotif:GGM.001105 GLYCOMOTIF_GGM; PUBDICT_GLYCAN_MOTIF; PUBDICT_MOTIF_GTC bGSL:acfe3120-4a43-4c27-9a34-89a201d70ea4 galactolipid glycolipids 3A EOG_VARKI_4E Galactolipids are a class of glycolipids characterized by one or more galactose residues attached to a lipid moiety. They are commonly found in plant membranes and play important roles in membrane structure and function. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch24/#:~:text=The%20synthesis%20of%20these,for%20normal%20photosynthesis%20to%20occur'] bGSL:6ac76f8b-710a-4e85-9a6e-69f8639733f7 ganglio-series glycosphingolipid Ganglio glycolipids; glycosylceramide b-series gangliosides; a-series gangliosides; c-series gangliosides; complex ganglioside; ganglioside; C-Series Gangliosides Oligosaccharide / Hemato- or Ganglio-Type 3A G00071MO GlycoMotif:GGM.001108 EOG_VARKI_4E; GLYCOMOTIF_GGM; PUBDICT_GLYCAN_MOTIF; PUBDICT_MOTIF_GTC Ganglio-series glycosphingolipids are a class of glycosphingolipids defined by a specific core oligosaccharide structure (Galβ1-3GalNAcβ1-4Galβ1-4Glcβ1-1Cer), which can be further extended and sialylated to form gangliosides. These molecules are predominant in the mammalian brain and are classified based on the number of sialic acid residues and their migration order on thin-layer chromatography, such as GM (mono), GD (di), and GT (tri) series. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch54/#:~:text=Glycosyltransferase-mediated,was%20employed%20twice%20%28Figure%2054.3%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch11/#:~:text=GSL%20series%20are%20expressed%20in,ganglio-series%20neutral%20sugar%20core'] ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch11/#:~:text=For%20example%2C%20in%20the%20widely%20used,as%20examples%20are%20major%20brain%20GSLs'] bGSL:71c565e3-6269-4c02-979f-d9044c692f0a ganglioside glycolipids; glycosphingolipids; sialylated glycolipid; sialoglycolipid; ganglio-series glycosphingolipid complex ganglioside; b-series gangliosides; a-series gangliosides; sialopentaosylceramide; c-series gangliosides 3A EOG_VARKI_4E Gangliosides are glycosphingolipids (glycolipids) characterized by one or more sialic acid residues linked to an oligosaccharide chain, which is attached to a ceramide lipid. As a subclass of sialylated glycosphingolipids, they are abundant in the nervous system, particularly the brain, and function as important cell surface molecules involved in cell signaling, recognition, and as receptors for toxins and viruses. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch07/#:~:text=Another%20striking%20example%20is%20the,membrane%20microdomains%20%28Chapter%2011%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch07/#:~:text=Although%20the%20precise%20mechanisms%20of,affected%20by%20glycosylation', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch44/#:~:text=When%20wild-type%20mice%20were%20treated,but%20prevented%20macrocephaly', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch04/#:~:text=Taken%20together%2C%20evidence%20indicates,topology%20of%20the%20claimed%20structures', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch07/#:~:text=There%20are%20many%20receptors%20whose,to%20these%20functions%20of%20glycans', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch11/#:~:text=GSL%20series%20are%20expressed%20in,ganglio-series%20neutral%20sugar%20core', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch11/#:~:text=Traditionally%2C%20all%20sialylated%20GSLs,is%20designated%20%E2%80%9CGM1%E2%80%9D%20%28Figure%2011.3%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch11/#:~:text=The%20biosynthesis%20of%20GSLs%20in%20the,of%20the%20%E2%80%9Cb-series%E2%80%9D%20gangliosides', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch11/#:~:text=Even%20in%20animals%20with%20predominantly,glycoprotein%20glycans%20%28Chapter%2014%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch11/#:~:text=The%20MHC%20class%20I-related%20molecule,receptor%20responsiveness%20to%20insulin', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch11/#:~:text=Another%20example%2C%20Tay%E2%80%93Sachs,to%20their%20lipooligosaccharide%20cores', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch11/#:~:text=These%20patients%20suffer%20severe,each%20with%20three%20GSL-binding%20sites', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch11/#:~:text=The%20changes%20result%20mainly%20from,Okajima%2C%20and%20Ryan%20N.%20Porell', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch15/#:~:text=As%20with%20the%20glycome%2C%20each%20cell,of%20Sias%20on%20capsules%20and%20O-antigens', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch15/#:~:text=Bacteria%20with%20close%20relationships,structures%20on%20glycoprotein%20glycans', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch15/#:~:text=Sias%20are%20released%20from,autophagy%20or%20phagocytosis', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch23/#:~:text=However%2C%20S.%20cerevisiae%20cells%20use,of%20%E2%88%BC14%20million%20base%20pairs.%20S', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch24/#:~:text=GIPCs%20are%20estimated%20to%20comprise%20up,membranes%20remain%20to%20be%20confirmed', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch26/#:~:text=However%2C%20arthropods%20possess%20their,core%20%28Gal%CE%B21-4Glc%CE%B2-ceramide%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch27/#:~:text=These%20mice%20shunt%20glycosphingolipid,genetically%20outbred%20populations', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch31/#:~:text=In%20each%20subunit%2C%20the%20%CE%B1-%20and,of%20the%20ganglioside%20%28Chapter%2020%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch31/#:~:text=Hemolysin%20%28UniProt%20P09545%29%20of,in%20cabbage%20butterfly%20larvae', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch32/#:~:text=A%20number%20of%20proteins%20are%20known%20to,and/or%20specificity%20is%20lacking', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch35/#:~:text=Mendelian%20disorders%20%28autosomal,GD1a%20and%20GT1b%20%28Chapter%2011%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch35/#:~:text=These%20findings%20suggest%20that,motif%20in%20its%20cytoplasmic%20tail', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch35/#:~:text=Siglec-11%20and%20Siglec-16%20are%20paired,is%20also%20present%20on%20microglia', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch41/#:~:text=Glycan-related%20interactions%20can,during%20embryogenesis%20%28Chapter%2015%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch46/#:~:text=In%20some%20studies%2C%20HS%20injections,%28the%20so-called%20HNK-1%20epitope%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch46/#:~:text=Following%20an%20intestinal%20infection,the%20human%20sialic%20acid%20Neu5Ac', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch47/#:~:text=Some%20tumor%20cells%20express%20small,a%20single%20oxygen%20atom%20%28Figure%2047.3%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch47/#:~:text=Many%20%E2%80%9Ctumor-specific%E2%80%9D%20monoclonal,signaling%20by%20numerous%20receptors', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch47/#:~:text=As%20a%20principal%20constituent%20of,the%20integrin%20signaling%20pathway', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch50/#:~:text=Treatment%20of%20proteoglycans%20with,and%20ion-exchange%20chromatography%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch50/#:~:text=Some%20pre-purification%20of%20the%20crude,TLC%20on%20silica%20plates', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch57/#:~:text=Currently%2C%20several%20new%20vaccines,failed%20to%20gain%20marketing%20approval', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch35/#:~:text=Mendelian%20disorders%20%28autosomal,GD1a%20and%20GT1b%20%28Chapter%2011%29'] ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch26/#:~:text=Chitin%20is%20a%20major%20component%20of%20the,designated%20as%20the%20arthroseries'] bGSL:48ab9dba-b6d9-4ff4-a7ac-42d6841cb064 globo-series glycosphingolipid Globo; globo-series glycospingolipid; globosides (glycosphingolipid class) glycolipids 3A G99312NX; G00072MO; G00061MO GSD:00066 GlycoMotif:GGM.001109; GlycoMotif:GGM.000070 EOG_VARKI_4E; GLYCOMOTIF_GGM; PUBDICT_GLYCAN_MOTIF; PUBDICT_MOTIF_GTC; GSD_GLYGEN_V1 Globo-series glycosphingolipids are a class of glycosphingolipids characterized by terminal α-galactose residues. They are the most abundant glycolipids in erythrocytes and are degraded by the enzyme α-galactosidase. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch11/#:~:text=GSL%20series%20are%20expressed%20in,ganglio-series%20neutral%20sugar%20core', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch44/#:~:text=Loss%20of%20this%20enzyme%20produces,glycolipids%20close%20to%20the%20membrane'] bGSL:14db23ad-99db-4458-a1f2-98c334dcaf4f glycoglycerolipid glycolipids 3A EOG_VARKI_4E Glycoglycerolipids are a class of glycolipids characterized by glycan moieties attached to the C-3 hydroxyl group of diacylglycerol or alkyl(acyl)glycerol, distinguishing them from glycosphingolipids. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch11/#:~:text=Likewise%2C%20glucosylceramide,distributed%20in%20microbes%20and%20plants'] bGSL:ace3eaa1-b29c-4f6a-923a-b858378199c5 glycolipids galactolipid; glycoglycerolipid; glycoinositolphospholipids; complex glycolipid; ganglioside; glycosphingolipids; ganglio-series glycosphingolipid; globo-series glycosphingolipid 3A EOG_VARKI_4E Glycolipids are glycoconjugates composed of a glycan moiety attached to a lipid. They include major classes such as brain glycolipids, which are abundant in neural tissue, as well as shorter chain variants. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch15/#:~:text=Early%20nomenclature%20of%20these,Kdn%29%20with%20a%20hydroxyl%20group%20at%20C-5', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch44/#:~:text=Saposins%20%28SAPs%29%2C%20also%20called,and%20Gaucher%27s%20disease'] bGSL:873c8c5c-6531-4656-8ba1-c9cea8bb0252 glycosaminoglycans GAGs sulfated glycosaminoglycan 3A EOG_VARKI_4E Glycosaminoglycans (GAGs) are linear polysaccharides composed of repeating acidic disaccharide units, typically containing a hexosamine and a hexose or hexuronic acid. These chains are often sulfated and are covalently attached to core proteins to form proteoglycans. GAGs, which include heparan sulfate, chondroitin sulfate, dermatan sulfate, and others, are critical for protein interactions and the structure of the extracellular matrix in eukaryotes. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch38/#:~:text=Several%20viruses%20and%20bacteria%20also,chain%20%28e.g.%2C%20antithrombin%20binding%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch38/#:~:text=In%20some%20cases%2C%20the%20interaction%20has,which%20is%20not%20entirely%20correct', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch38/#:~:text=Thus%2C%20to%20bind%20a%20GAG%20chain%2C%20the,under%20physiological%20conditions', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch38/#:~:text=Finally%2C%20one%20should%20keep%20in%20mind,inhibitor%20have%20GAG-binding%20sites', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch05/#:~:text=However%2C%20the%20import%20is,of%20misfolded%20glycoproteins', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch05/#:~:text=Mutant%20mammalian%20cell%20lines%20also,clue%20to%20the%20substrate%20specificity', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch07/#:~:text=A%20further%20structural%20function%20of,and%20immune%20regulatory%20proteins', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch17/#:~:text=The%20amino-terminal%20portion%20of%20the,%E2%80%9Cpart-time%E2%80%9D%20proteoglycans', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch17/#:~:text=In%20fact%2C%20many%20proteoglycans%20show,discussed%20further%20in%20Chapter%2038', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch26/#:~:text=The%20principal%20disaccharide%20species,are%20also%20represented%20in%20Drosophila', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch28/#:~:text=Based%20on%20this%20information%2C%20it%20is,using%20immobilized%20GAG%20chains', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch28/#:~:text=As%20mentioned%20above%2C%20many,can%20even%20suggest%20potential%20ligands', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch38/#:~:text=To%20determine%20the%20physiological,in%20their%20ability%20to%20bind%20proteins', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch38/#:~:text=In%20retrospect%2C%20this%20strategy%20was,%CE%B1-helices%2C%20%CE%B2-strands%2C%20and%20loops', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch38/#:~:text=In%20GAG-binding%20proteins%2C%20the,a%20small%20segment%20of%20the%20GAG%20chain', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch38/#:~:text=Three%20structural%20elements%20that,diffraction%20to%202.6-%C3%85%20resolution', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch38/#:~:text=The%20binding%20sites%20in%20GAG%20chains%20in,little%20oligosaccharide%20specificity', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch38/#:~:text=A%20final%20point%20of%20note%20is%20that%20the,HS%20in%20a%20calcium-dependent%20manner', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch44/#:~:text=GAGs%2C%20including%20heparan%20sulfate,with%20mutations%20in%20the%20same%20gene', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch44/#:~:text=Sulfate%20is%20first%20removed%20by,of%20%CE%B2GlcA%20and%20%CE%B2GalNAc%20%28Chapter%2017%29'] ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch01/#:~:text=In%20contrast%2C%20eukaryotic,%28i.e.%2C%20N-%20or%20O-sulfate%20groups%29'] bGSL:7bd3304e-d3e0-5ca0-bffb-6383a796ed65 glycosphingolipids GSLs glycolipids b-series gangliosides; ganglioside 3A EOG_VARKI_4E Glycosphingolipids (GSLs) are a subclass of glycolipids composed of a glycan (oligosaccharide) linked to a ceramide lipid moiety. They are major components of animal cell membranes, synthesized by the stepwise addition of sugars to ceramide, and are classified based on their glycan structures. GSLs play important roles in membrane structure, cell–cell recognition, and signal transduction. They are degraded in lysosomes, and defects in their catabolism can result in pathological accumulation. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch11/#:~:text=Ronald%20L.%20Schnaar%2C%20Roger%20Sandhoff%2C,as%20membrane%20anchors%20%28Chapter%2012%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch11/#:~:text=For%20example%2C%20in%20the%20widely%20used,as%20examples%20are%20major%20brain%20GSLs', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch11/#:~:text=Glycosphingolipids%20%28GSLs%29%20are,and%20adsorption%20chromatographies', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch25/#:~:text=elegans%20is%20similar%20to%20the%20chains,%28GSLs%29%20%28Chapter%2011%29%20in%20C', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch11/#:~:text=Ronald%20L.%20Schnaar%2C%20Roger%20Sandhoff%2C,as%20membrane%20anchors%20%28Chapter%2012%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch11/#:~:text=This%20chapter%20describes%20the,referred%20to%20as%20sphingoid%20bases', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch11/#:~:text=Animal%20cells%20synthesize%20various,clusters%20or%20%E2%80%9Cganglia%E2%80%9D%20in%20the%20brain', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch11/#:~:text=Likewise%2C%20glucosylceramide,distributed%20in%20microbes%20and%20plants', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch11/#:~:text=GalCer%20and%20its%20analog%20sulfatide%2C,of%20the%20epidermis%20%28see%20below%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch11/#:~:text=GSL%20series%20are%20expressed%20in,ganglio-series%20neutral%20sugar%20core', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch11/#:~:text=Traditionally%2C%20all%20sialylated%20GSLs,is%20designated%20%E2%80%9CGM1%E2%80%9D%20%28Figure%2011.3%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch11/#:~:text=For%20example%2C%20in%20the%20widely%20used,as%20examples%20are%20major%20brain%20GSLs', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch11/#:~:text=Glycosphingolipids%20%28GSLs%29%20are,and%20adsorption%20chromatographies', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch11/#:~:text=Because%20of%20their%20amphipathic,viruses%2C%20bacteria%2C%20or%20cells%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch11/#:~:text=Glycan%20composition%20is%20determined,methods%20described%20in%20Chapter%2050', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch11/#:~:text=It%20is%20flipped%20to%20the%20luminal%20side,structural%20diversity%20%28Figure%2011.3%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch11/#:~:text=The%20biosynthesis%20of%20GSLs%20in%20the,of%20the%20%E2%80%9Cb-series%E2%80%9D%20gangliosides', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch11/#:~:text=In%20contrast%2C%20guinea%20pig%2C%20mouse%2C,storage%20diseases%20%28Chapter%2044%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch11/#:~:text=When%20endosomes%20fuse%20with%20primary,water-soluble%20hydrolytic%20enzymes', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch11/#:~:text=Saposins%20are%20thought%20to%20bind%20to,membrane%20molecules', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch11/#:~:text=However%2C%20they%20are%20not%20uniformly,associate%20with%20lipid%20rafts', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch11/#:~:text=On%20the%20cytoplasmic%20side%2C%20acylated,the%20outside%20to%20the%20inside%20of%20cells', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch11/#:~:text=Thus%2C%20GSLs%20may%20act%20as,to%20plasma%20membrane%20glycolipids', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch11/#:~:text=Natural%20multivalency%20adds%20unique,and%20even%20differentiate', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch11/#:~:text=Ceramide%20is%20a%20key%20component%20of%20the,regulation%20of%20signal%20transduction', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch11/#:~:text=These%20results%20support%20the,found%20on%20human%20leukocytes', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch11/#:~:text=One%20of%20the%20selectins%2C%20E-selectin%2C,recognition%20to%20activate%20NKT%20cells', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch11/#:~:text=Ganglioside%20GM3%2C%20for%20example%2C,with%20embryonic%20lethality%20in%20mice', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch11/#:~:text=This%20mutation%20evidently%20left%20some,in%20activator%20proteins%20%28Chapter%2044%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch11/#:~:text=These%20bacteria%20produce%20near-exact,gain%20access%20to%20cells%20%28Chapter%2037%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch11/#:~:text=These%20patients%20suffer%20severe,each%20with%20three%20GSL-binding%20sites', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch11/#:~:text=In%20contrast%2C%20tetanus%20and%20related,in%20glycolipid%20biosynthesis', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch25/#:~:text=elegans%20is%20similar%20to%20the%20chains,%28GSLs%29%20%28Chapter%2011%29%20in%20C', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch25/#:~:text=Mutations%20in%20individual%20steps%20were,N-glycans%2C%20GSLs%2C%20and%20GPI%20anchors', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch26/#:~:text=Chitin%20is%20a%20major%20component%20of%20the,designated%20as%20the%20arthroseries', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch26/#:~:text=However%2C%20arthropods%20possess%20their,core%20%28Gal%CE%B21-4Glc%CE%B2-ceramide%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch26/#:~:text=Neutral%20arthroseries%20glycans%20are,diversity%20has%20also%20been%20identified', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch45/#:~:text=Deficiency%20of%20tissue-nonspecific,seizures%20or%20a%20shortened%20life%20span', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch45/#:~:text=The%20patients%E2%80%99%20plasma%20GSLs%20are,the%20progressive%20gait%20disorder', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch11/#:~:text=Sphinganine%20is%20the%20same%20structure,in%20the%20kidney%20and%20the%20brain', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch11/#:~:text=In%20skin%2C%20it%20is%20a%20precursor%20of,in%20tissue-specific%20patterns', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch34/#:~:text=Acute%20and%20chronic%20inflammatory,expressing%20the%20SLex%20antigen'] ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch11/#:~:text=Saposins%20are%20thought%20to%20bind%20to,membrane%20molecules', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch11/#:~:text=They%20typically%20result%20from,deterioration%20of%20brain%20function', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch26/#:~:text=Mutations%20that%20affect%20the%20first,because%20of%20reduced%20Ras%20signaling'] bGSL:ca4368ca-299a-45db-8ea4-3e4f17d06e7f glycosyldiacylglycerolipid glycosyldiacylglycerolipids 3A EOG_VARKI_4E A type of glycolipid composed of one or more monosaccharides attached to a diacylglycerol backbone, frequently featuring α1-6-linked galactopyranose residues. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch23/#:~:text=Finally%2C%20the%20xylans%20of%20this,not%20homologous%20to%20human%20enzymes'] bGSL:42d6b76a-b3f8-4566-b53b-016a6c5d094f isoglobo-series glycosphingolipid Glycosphingolipid Isoglobo series 3A G00012MO GlycoMotif:GGM.001101 GLYCOMOTIF_GGM; PUBDICT_GLYCAN_MOTIF; PUBDICT_MOTIF_GTC bGSL:8edfb75f-8504-4974-b287-ddda3983a7fa keratan sulfate–related glycan antigens KS–related antigens 3A EOG_VARKI_4E Glycan antigens structurally related to keratan sulfate, including motifs such as the tetrasaccharide Galβ1-3GlcNAcβ1-3Galβ1-4GlcNAc, which are recognized by specific monoclonal antibodies such as TRA-1-60 and TRA-1-81. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch41/#:~:text=For%20example%2C%20stage-specific,play%20key%20roles%20in%20hemostasis'] bGSL:84af9fa6-f891-4343-b9cf-ebb6a2717df8 lacto-series glycosphingolipid 3A G00069MO GlycoMotif:GGM.001106 EOG_VARKI_4E; GLYCOMOTIF_GGM; PUBDICT_GLYCAN_MOTIF; PUBDICT_MOTIF_GTC Lacto-series glycosphingolipids are a class of glycosphingolipids defined by a core structure containing N-acetyllactosamine (LacNAc) repeats. These glycolipids are especially prominent in secretory organs and play important roles in cellular recognition and membrane structure. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch11/#:~:text=GSL%20series%20are%20expressed%20in,ganglio-series%20neutral%20sugar%20core'] bGSL:691b1c25-2daf-5cbd-80a5-e1e4788fa484 Lewis antigens Lewis-type structures; Lewis type glycans; Lewis blood group antigens 3A EOG_VARKI_4E Lewis antigens are a family of fucosylated glycan epitopes, including Lewis a, b, x, and y, that function as blood group antigens and mediate cell-cell interactions. These structures are characterized by the addition of L-fucosyl residues to a glycan backbone, resulting in branched motifs commonly found on glycoproteins and glycolipids. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch14/#:~:text=This%20is%20because%20H.%20pylori%20binds,with%20an%20ABO-incompatible%20type', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch14/#:~:text=%28more...%29%20Expression%20of%20Lea%20and,a%20hemolytic%20transfusion%20reaction', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch25/#:~:text=The%20cattle%20parasite%20D.%20viviparous,Examples%20of%20nematode%20glycans', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch14/#:~:text=Because%20of%20structural,function%20in%20the%20pathogenesis%20of%20H', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch46/#:~:text=Numerous%20gastrointestinal,explaining%20this%20association'] ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch03/#:~:text=The%20oligosaccharide%20is%20built%20on%20an,structures%20%28Figure%203.4D%29'] bGSL:b9824496-840f-4973-81bd-7f3b589f1338 lipoglycan 3A EOG_VARKI_4E Lipoglycans are a broad class of glycoconjugates in which a glycan, such as an oligosaccharide or polysaccharide, is covalently linked to a lipid moiety. These molecules contribute to cell membrane structure and function. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch22/#:~:text=Methanosarcina%20species%20can%20further,number%20of%20proteins%20%28Figure%2022.1%29'] bGSL:2242a545-9d0f-4c2a-8d69-f0b257104a15 lipophosphoglycan LPG 3A EOG_VARKI_4E Lipophosphoglycan (LPPG) is a major surface glycoconjugate of Leishmania parasites, consisting of a phosphoglycan chain linked to a lipid anchor. It functions as a virulence factor and plays a key role in parasite biology. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch43/#:~:text=Leishmania%20LPG%20and%20LPPG%20are,inflammatory%20responses'] ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch43/#:~:text=Leishmania%20LPG%20and%20LPPG%20are,inflammatory%20responses'] bGSL:a5aa393a-272a-416d-a2d3-f5ffeae6e648 lipopolysaccharide LPS 3A G00022MO EOG_VARKI_4E; PUBDICT_MOTIF_GTC Lipopolysaccharide is a major glycolipid component of the outer membrane of Gram-negative bacteria, composed of lipid A, a core oligosaccharide, and an O-antigen polysaccharide. It acts as a potent antigen and pathogen-associated molecular pattern (PAMP). ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch03/#:~:text=LPSs%20carry%20long%20polysaccharides,diverse%20set%20of%20polymer%20structures', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch03/#:~:text=Some%20polymers%20are%20known%20under,affect%20polysaccharide%20properties'] ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch03/#:~:text=The%20interactions%20of%20bacteria%20with,leaflet%20of%20the%20outer%20membrane', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch05/#:~:text=Deoxyhexoses%20are%20often,CDP-glucose%20dehydratase', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch15/#:~:text=Sias%20in%20capsular%20polysaccharides,to%20Sia%20pathways%20of%20vertebrates', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch34/#:~:text=MBL%2C%20conglutinin%2C%20CL-43%2C%20CL-46%2C,is%20further%20augmented%20by%20SP-A', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch40/#:~:text=In%20more%20advanced%20eukaryotes%2C%20this,fragments%20as%20DAMPs%20%28Figure%2016.6%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch52/#:~:text=The%20problem%20here%20is%20that%20glycans,functions%20have%20been%20developed'] bGSL:cc09ab09-65e2-45ff-bb5e-f16b02b7b507 mollu-series glycosphingolipid Glycosphingolipid Mollu series 3A G00015MO GlycoMotif:GGM.001104 GLYCOMOTIF_GGM; PUBDICT_GLYCAN_MOTIF; PUBDICT_MOTIF_GTC bGSL:6ece77a3-f44b-475b-b7f7-58e7ef309dcf mucin-type O-glycans O-GalNAc glycans O-glycans O-GalNAc-linked sialoglycans; O-GalNAc core structures 3A GSD:00177 GSD_GLYGEN_V1; EOG_VARKI_4E Related synonym extracted from gsdv1 edge. See edges.jsonl for the linked subject term. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch31/#:~:text=Living%20systems%20have%20evidently,peptide%20and%20UDP-GalNAc%20as%20donor', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch06/#:~:text=The%20glycosyltransferases%20that,regions%20of%20the%20folded%20protein', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch10/#:~:text=Inka%20Brockhausen%2C%20Hans%20H.%20Wandall%2C,and%20Gal%20and%20GlcNAc%20by%20sulfation', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch23/#:~:text=S.%20cerevisiae%20contributed%20to,found%20in%20vertebrates.%20However%2C%20S', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch27/#:~:text=Indeed%2C%20developmental%20changes%20in,against%20microbial%20infection', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch34/#:~:text=This%20ligand%20carries%20SLex%20on%20its,the%20surface%20of%20activated%20platelets', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch48/#:~:text=For%20example%2C%20the%20plant%20lectin%20ConA,cells%2C%20and%20glycan%20microarrays', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch45/#:~:text=FCMD%20is%20one%20of%20the%20most%20common,causes%20familial%20tumoral%20calcinosis', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch26/#:~:text=Systematic%20mutational%20and,of%20three%20different%20core%20structures'] bGSL:ef76739d-5693-4ca3-9c51-a74c9e46c314 muco-series glycosphingolipid Glycosphingolipid Muco series 3A G00013MO GlycoMotif:GGM.001102 GLYCOMOTIF_GGM; PUBDICT_GLYCAN_MOTIF; PUBDICT_MOTIF_GTC bGSL:c64aad0e-0352-47b6-bb5e-d0a724dbbc59 N-glycan asparagine–N-linked glycan; N-linked; N-linked oligosaccharide 3A G78059CC; G90889KG; G28330DZ; G00027MO GSD:00113 GSD_GLYGEN_V1; EOG_VARKI_4E; SUGARBIND; PUBDICT_MOTIF_GTC The carbohydrate portion of a glycoprotein that has a glycan linked through the nitrogen of an asparagine side-chain.[CHEBI:59520] Our study identifies extracellular N-linked glycans-and the glycoprotein neurexin 1β specifically-as key modulators of neuronal uptake of αSacetyl, drawing attention to the potential therapeutic value of αSacetyl-glycan interactions.[PMID:31211781] bGSL:52625ff9-f784-4b93-b4d6-83f073e2fc4f neolacto-series glycosphingolipid 3A G00070MO GlycoMotif:GGM.001107 EOG_VARKI_4E; GLYCOMOTIF_GGM; PUBDICT_GLYCAN_MOTIF; PUBDICT_MOTIF_GTC Neolacto-series glycosphingolipids are a class of glycosphingolipids (GSLs) defined by a neutral core sequence. They are commonly found on certain hematopoietic cells, including leukocytes, in mammals. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch11/#:~:text=In%20skin%2C%20it%20is%20a%20precursor%20of,in%20tissue-specific%20patterns', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch11/#:~:text=GSL%20series%20are%20expressed%20in,ganglio-series%20neutral%20sugar%20core'] bGSL:712126ee-26fa-47cf-90b5-9328b4d0b6e0 O-GalNAc core structures O-GalNAc cores; O-GalNAc core mucin-type O-glycans 3A G39738WL GlycoMotif:GGM.001034 EOG_VARKI_4E; GLYCOMOTIF_GGM O-GalNAc core structures are conserved oligosaccharide cores formed by the extension of the initial O-linked GalNAc residue on serine or threonine. These structures, known as cores 1–4, serve as the foundational building blocks for complex O-GalNAc glycans, particularly in mucins, and are essential for O-glycan biosynthesis in vertebrates. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch10/#:~:text=However%2C%20core%203%20and%204%20O-GalNAc,sugars%20or%20functional%20groups'] ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch10/#:~:text=The%20first%20mucin%20polypeptide%20gene,structures%20%28cores%201%E2%80%934%3B%20Table%2010.1%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch14/#:~:text=Also%20discussed%20are%20milk,%28LacNAc%29%20%28Figure%2014.2%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch55/#:~:text=%28more...%29%20A%20number%20of%20inhibitors,to%20another%20is%20often%20difficult'] bGSL:2aee2976-6a71-491c-8087-5b3c82fa4de8 O-glycans O-linked oligosaccharide O-mannose glycan; O-GalNAc-linked sialoglycans; complex O-glycan; O-fucose glycan; 2,6-branched O-mannose; mucin-type O-glycans O-glycan 3A EOG_VARKI_4E O-glycans are a class of glycans covalently attached to the serine or threonine residues of proteins via O-glycosidic bonds. Common in animals, they display diverse core structures often containing GalNAc, GlcNAc, Gal, fucose, and sialic acid. O-glycans are synthesized in the Golgi apparatus and play important roles in protein function, stability, and cell-cell interactions. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch34/#:~:text=In%20this%20regard%2C%20whereas,and%20some%20memory/effector%20T%20cells', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch46/#:~:text=Underglycosylated%20IgA1%20has%20the,in%20preventing%20its%20loss%20with%20age', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch52/#:~:text=The%20Australian%20company%2C%20Proteome,and%20in%20cell%E2%80%93cell%20communication', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch01/#:~:text=Remarkably%20little%20is%20still%20known,microorganisms%20and%20various%20toxins', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch09/#:~:text=Many%20of%20these%20structures%20are,of%20GNPTAB%20and%20GNPTG%29%20%28Figure%209.4%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch14/#:~:text=Type-1%2C%20-2%2C%20and%20-3%20H%2C%20A%2C%20and%20B,inactive%20A/B%20glycosyltransferase', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch41/#:~:text=Infection%20and%20inflammation%20can,increased%20risk%20of%20infections', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch44/#:~:text=The%20great%20majority%20of%20N-%20and,degradative%20enzymes%20%28Table%2044.1%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch44/#:~:text=Glycosphingolipids%20%28Chapter%2011%29,in%20this%20chapter.%20%28SAP%29%20Saposin', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch45/#:~:text=The%20discovery%20of%20CDG%20defects,degrees%20of%20altered%20glycosylation', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch49/#:~:text=Thus%2C%20glycosylation%20is%20often,facilitating%20their%20crystallization', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch50/#:~:text=Commonly%20used%20tagging%20reagents,hydrolysis%20of%20the%20polymeric%20chain', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch60/#:~:text=Finally%2C%20the%20rapidly%20expanding,glycans%20will%20continue%20to%20improve', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch05/#:~:text=Under%20stressful%20conditions%2C,some%20%E2%80%9Cleakiness%E2%80%9D%20in%20such%20mutants', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch05/#:~:text=Biosynthesis%20and%20interconversion,contain%20glucuronic%20acid%20as%20well', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch05/#:~:text=UDP-GlcA%20is%20used%20primarily%20for%20GAG,5.2%3B%20Chapter%2017%29%20in%20vertebrates', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch17/#:~:text=Vascular%20endothelial%20cells%2C%20for,than%20100%20chains%20%28e.g.%2C%20aggrecan%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch44/#:~:text=Exoglycosidases%20cleave%20the,linkages%20of%20larger%20chains', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch46/#:~:text=Another%20model%20is%20aminonucleoside,IgA1%20with%20O-glycan%20truncations', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch51/#:~:text=Current%20glycoproteomics%20methods,have%20appeared%20over%20recent%20years', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch01/#:~:text=A%20glycoprotein%20is%20a%20glycoconjugate,are%20clustered%20%28closely%20spaced%29', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch18/#:~:text=Glycosylation%20that%20is%20more,of%20modification%20with%20O-GalNAc', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch10/#:~:text=Dense%20O-glycosylation%20of%20mucin,labile%20O-acetyl%20or%20sulfate%20esters'] ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch43/#:~:text=Life%20cycle%20of%20Schistosoma%20species%2C,polyfucose%20branches%20%28Figure%2043.8%29'] bGSL:991f16af-5047-41eb-ab0f-a0e8c5ffe611 O-xylose-linked glycosaminoglycan O-xylose-linked GAG chains sulfated glycosaminoglycan; xylosylated glycans 3A EOG_VARKI_4E A glycosaminoglycan (GAG) chain that is covalently attached to a core protein through an O-linked xylose residue. This structure includes dermatan sulfate (DS), chondroitin sulfate (CS), and heparan sulfate (HS), all of which share a common core tetrasaccharide linkage region. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch44/#:~:text=GAGs%2C%20including%20heparan%20sulfate,with%20mutations%20in%20the%20same%20gene', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch44/#:~:text=Galactose-6-SO4%20sulfatase%20is%20the,sulfatase%20deficiency%20%28MSD%29'] bGSL:ec8b7eb9-adcb-4216-8e79-e8adba165723 P blood group antigens 3A EOG_VARKI_4E P blood group antigens are glycan structures, specifically glycosphingolipids, present on red blood cells. They serve as targets for specific antibodies, influencing blood group compatibility, and also act as receptors for certain bacterial adhesins, playing a role in susceptibility to urinary tract infections. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch46/#:~:text=Patients%20with%20the%20rare%20disorder,occurs%20after%20warming%20to%2037%C2%B0C'] ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch42/#:~:text=The%20structural%20proteins%20for%20pilus,in%20the%20%E2%80%9Cwhooping%20cough%E2%80%9D%20disease'] bGSL:9545f84e-b887-402a-a0d6-2a88613bb46a SSEA SSEA-4; SSEA-1; SSEA-3 3A G85497PI; G99053DY PUBDICT_GLYCAN_MOTIF bGSL:801e5992-e51d-499d-9240-55b09201d19d 2'-fucosyllactose 2'FL blood group H type 6 3B EOG_VARKI_4E; PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV 2'-fucosyllactose is a human milk oligosaccharide composed of lactose with an α1-2-linked fucose attached to the galactose residue. It is known to inhibit pathogen binding by mimicking host cell surface receptors. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch40/#:~:text=The%20amount%20and%20composition%20of%20HMOs,and%20modulate%20cytokine%20production'] bGSL:5fa9e691-e4e1-4499-ab87-25467d245304 2-Deoxyglucose 3B PUBDICT_GLYCONAVI_NAME bGSL:b97b53fb-1f4a-432c-b56d-f645cc26daa4 2-Deoxyribose 3B PUBDICT_GLYCONAVI_NAME bGSL:dc52c9a1-6b9a-41a7-907b-e9ad31833eda 3-O-sulfated galactose 3-O-sulfated Gal 3B G40843KY EOG_VARKI_4E; GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE A galactose residue that is modified by sulfation at the 3-O position. This modification is recognized as a ligand involved in the clearance of pituitary hormones from the bloodstream. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch31/#:~:text=When%20CD206%20dimerizes%20on%20cell,lectins%2C%20enzymes%2C%20and%20toxins'] bGSL:ac556318-44a6-41bc-aae1-29516f0adf7c 3-O-sulfated GlcNS6S 6-O-sulfated glucosamine 3B EOG_VARKI_4E A glucosamine residue in heparin or heparan sulfate that is N-sulfated, 6-O-sulfated, and further modified by 3-O-sulfation. This specific modification, known as 3-O-sulfated GlcNS6S, is critical for antithrombin–heparin interaction and is also recognized by certain viruses, highlighting its functional significance in biological processes. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch38/#:~:text=Three%20structural%20elements%20that,diffraction%20to%202.6-%C3%85%20resolution'] ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch42/#:~:text=In%20many%20cases%2C%20HS%20is%20a%20coreceptor%2C,structure%2C%203-O-sulfation%20on%20GlcNAc'] bGSL:f633b452-ebc4-440a-9fbc-80aaf0864902 6-O-sulfated glucosamine 3-O-sulfated GlcNS6S 3B EOG_VARKI_4E Glucosamine residues within heparan sulfate chains that are sulfated at the 6-O position. These residues are subject to modification by endosulfatases (SULFs), which can alter their sulfation status and influence the biological properties of the glycan chain. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch17/#:~:text=An%20epimerase%20%28GLCE%29%2C%20different,cleave%20the%20chains%20at%20limited%20sites'] bGSL:c1ee7a92-26a4-4f1e-a63d-898260831dc2 9-O-acetyl sialic acid 9-O-acetylated Sia; 9-O-Ac-Sia; 9-O-acetylated-SA O-acetylated sialic acids; Neuraminic acid; N-acetylneuraminic acid 3B G47325QT GSD:00010 GSD_GLYGEN_V1; EOG_VARKI_4E; GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE N-acetyl-9-O-acetyl-alpha-neuraminic acid is a member of the class of N-acetylneuraminic acids that is alpha-neuraminic acid which has acetylated on N-5 and O-9. It has functional parent alpha-neuraminic acid.[CHEBI:84941] Levels of 9-O-acetyl sialic acid provide a distinct way to define progenitors and thus facilitate the study of hematopoietic differentiation.[PMID:31411667] bGSL:73dbcfb5-da67-4450-b550-1d54a70f0859 Acosamine 3B PUBDICT_GLYCONAVI_NAME bGSL:0744deb3-0e63-4b36-a25a-49dce8213f74 Allose 3B PUBDICT_GLYCONAVI_NAME bGSL:bdc805ef-7769-4b2b-a978-1bbc033dd33a Altrose 3B PUBDICT_GLYCONAVI_NAME bGSL:538a257e-cbc9-4639-a1f7-b52c19e3dabc Amicetose 3B PUBDICT_GLYCONAVI_NAME bGSL:01c91772-e2e6-4b4a-9413-5180305c903d Apiose 3B PUBDICT_GLYCONAVI_NAME bGSL:8eab3c31-690c-41e0-951b-b7963f6ba93a Arabinose 3B PUBDICT_GLYCONAVI_NAME bGSL:9585fe1c-0858-449f-9e9c-c178ef6cd1c9 Arcanose 3B PUBDICT_GLYCONAVI_NAME bGSL:de5e10fd-beb6-4091-a481-145f29c6c60f Ascarylose 3B PUBDICT_GLYCONAVI_NAME bGSL:7cb15c97-014c-4970-8a83-6b1d18f2b764 Ascorbic acid 3B PUBDICT_GLYCONAVI_NAME bGSL:26d47e77-b3eb-4a2d-8b56-12f3ce2c2c4e Bacillosamine 3B PUBDICT_GLYCONAVI_NAME bGSL:44c38b26-626b-4027-820e-3f5a5a51672f Boivinose 3B PUBDICT_GLYCONAVI_NAME bGSL:8c5f5123-9ab8-4db7-900e-24e5b3d2f1b3 cellobiose 3B G55560AP EOG_VARKI_4E; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; PUBDICT_GLYCONAVI_NAME Cellobiose is a disaccharide composed of two β-1,4-linked glucose residues and serves as the repeating unit of cellulose. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch03/#:~:text=The%20torsion%20angles%20are%20referred%20to,and%20maltose%2C%20respectively', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch03/#:~:text=Figure%203.2%20depicts%20these,most%20complex%20polymers%20in%20nature'] bGSL:2e54fff4-5d2f-4357-b566-63360be5a996 cellotriose 3B G50026IZ PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; PUBDICT_GLYCONAVI_NAME bGSL:b07e8344-aa4d-48b9-8753-2e1fcaccd70e Chacotriose 3B PUBDICT_GLYCONAVI_NAME bGSL:e1ae8351-acef-419f-a466-791982fc347e Chalcose 3B PUBDICT_GLYCONAVI_NAME bGSL:1b501923-0747-4784-b2b7-681ac7f7c983 chitobiose Man3 3B G07982RO EOG_VARKI_4E; SUGARBIND; PUBDICT_GLYCAN_MOTIF Chitobiose is a disaccharide composed of two β(1→4)-linked N-acetylglucosamine (GlcNAc) units, forming the core structure of N-glycans. In some biological contexts, this chitobiose core can be elongated by additional monosaccharides, particularly in cases involving defects in mannosyltransferase activity or in certain parasitic organisms, resulting in extended chitobiose motifs. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch39/#:~:text=NGLY1%20recognizes%20only%20misfolded%20or,%28ER%29%2C%20cytoplasm%2C%20and%20lysosomes'] ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch45/#:~:text=In%20recent%20years%2C%20it%20has%20been%20shown,have%20similar%20defects%20%28Chapter%2049%29'] ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch25/#:~:text=The%20cattle%20parasite%20D.%20viviparous,Examples%20of%20nematode%20glycans'] bGSL:7764829e-bb94-4ae0-970d-c42372d1edea Cladinose 3B PUBDICT_GLYCONAVI_NAME bGSL:fda78f4b-e583-4587-be6b-afe04ffe2220 Colitose 3B PUBDICT_GLYCONAVI_NAME bGSL:4a461f04-0dc3-4cf7-b4fc-7f0c86b40ec8 Cymarose 3B PUBDICT_GLYCONAVI_NAME bGSL:dfeeea91-9f4e-4401-8cb5-8186bf026c10 D-Fucitol D-fucitol 3B PUBDICT_GLYCONAVI_NAME bGSL:3858f80c-8214-4d0b-9443-be5e83989437 D-Galactosaminitol 3B PUBDICT_GLYCONAVI_NAME bGSL:694f3956-fd58-4fb9-9f42-3be6d8896fcf Daunosamine 3B PUBDICT_GLYCONAVI_NAME bGSL:cb355b2f-9f3a-496c-95bf-32fd5154d70f Desosamine 3B PUBDICT_GLYCONAVI_NAME bGSL:3b89634a-12d9-47a0-a29d-22df92870663 di-N-acetylbacillosamine diNAcBac 3B EOG_VARKI_4E Di-N-acetylbacillosamine (diNAcBac) is a bacterial monosaccharide containing two N-acetyl groups, and is commonly found at the reducing end of certain bacterial N-linked oligosaccharides. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch21/#:~:text=jejuni%2C%20Helicobacter%20pylori%2C%20and,known%20as%20S-layer%20proteins'] bGSL:11c39d6d-e46b-4185-a404-92d9f8b099c3 Diginose 3B PUBDICT_GLYCONAVI_NAME bGSL:9d96a64d-0141-4bbc-acd2-c8cec9a8940f Digitalose 3B PUBDICT_GLYCONAVI_NAME bGSL:7ded2ec8-c070-4817-b4b8-82b5e479dcdb Digitoxose 3B PUBDICT_GLYCONAVI_NAME bGSL:7174169e-58ea-4bc8-92d5-8514546a08fb Erythrose 3B PUBDICT_GLYCONAVI_NAME bGSL:3d4ef40c-5ea8-43b4-99d8-79d6b9bab3d0 Erythrulose 3B PUBDICT_GLYCONAVI_NAME bGSL:4aa63955-0296-4765-93f0-d7e6d3733ec1 Evalose 3B PUBDICT_GLYCONAVI_NAME bGSL:0953faa0-90b2-4188-ab41-e17212e48e86 Evernitrose 3B PUBDICT_GLYCONAVI_NAME bGSL:b997d7c9-077d-4095-9d34-378b64fb20ca Forosamine 3B PUBDICT_GLYCONAVI_NAME bGSL:1f140d73-149f-4c4f-a2b1-12feb062927b Fructose 3B PUBDICT_GLYCONAVI_NAME bGSL:b915b61e-f002-43da-921d-14b890faec2c Fucosamine 3B PUBDICT_GLYCONAVI_NAME bGSL:b70e50f9-8068-4c81-88e1-b949f95c2af2 fucose L-Fucose Fuc terminal α-linked fucose; terminal fucose; Outer arm fucose; core-fucosylated glycan 3B G82576YO SUGARBIND; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCONAVI_NAME bGSL:f11a7dd1-74a2-4e2d-a8bc-cb66771433eb galabiose Digalactoside 3B G62763GO EOG_VARKI_4E; SUGARBIND; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV Galabiose is a disaccharide composed of two galactose residues linked by an alpha1-4 glycosidic bond (Galα1-4Gal). It serves as a recognition motif for certain bacterial toxins and adhesins, and is found in glycolipids and glycoproteins, including as part of glycosphingolipids where it can be linked to ceramide. Galabiose-containing structures are present in the large intestine epithelium and function as receptors for specific pathogens. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch37/#:~:text=There%2C%20the%20enzymatic%20A1%20chain,receptor%20Gb3%20results%20in%20cell%20death', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch14/#:~:text=This%20syndrome%20is%20distinct%20from%20CAD,following%20infection%20in%20utero', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch37/#:~:text=The%20columnar%20epithelium%20that%20lines,further%20illustrated%20by%20E.%20coli%20K99'] ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch37/#:~:text=Mice%20lacking%20the%20gene%20encoding%20the,Thus%2C%20Bacterioides%2C%20Clostridium%2C%20E'] ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch37/#:~:text=The%20columnar%20epithelium%20that%20lines,further%20illustrated%20by%20E.%20coli%20K99'] bGSL:1e83af4d-4381-476e-bfbf-99325690cd77 Galactosamine 3B PUBDICT_GLYCONAVI_NAME bGSL:21d46b1f-28d1-48cb-9b7d-78133d445b6b Galactose Gal β6-linked galactose 3B G68158BT; G65889KE SUGARBIND; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCONAVI_NAME bGSL:a6858506-9beb-4d05-84c1-0774de77c5b9 Garosamine 3B PUBDICT_GLYCONAVI_NAME bGSL:d67743d6-3c87-466f-ae8e-339afd0e4f02 Gentianose 3B PUBDICT_GLYCONAVI_NAME bGSL:e44c377b-7cea-42b7-b598-2589c850a3e4 gentiobiose 3B G47329OU PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; PUBDICT_GLYCONAVI_NAME bGSL:65066dc3-df22-4cee-a447-3e94f7fe3b56 Glucosamine 3B PUBDICT_GLYCONAVI_NAME bGSL:2d494c97-10f4-450d-b5bb-0719aa4c8214 Glucosaminitol 3B PUBDICT_GLYCONAVI_NAME bGSL:2b93dcb5-f832-4fa7-9155-13ad91935e34 Glucose D-Glucose Glc 3B G15021LG SUGARBIND; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCONAVI_NAME bGSL:8dd48072-cfe3-4645-828d-24ec6ffdf571 Glyceraldehyde 3B PUBDICT_GLYCONAVI_NAME bGSL:b27a6a27-480a-43d9-8712-94bc35613779 Glycerone 3B PUBDICT_GLYCONAVI_NAME bGSL:89ddd2a8-2f55-4664-afed-da121e31e621 Gulose 3B PUBDICT_GLYCONAVI_NAME bGSL:f077d99d-55fe-45e1-afea-2d7110edd449 Hamamelose 3B PUBDICT_GLYCONAVI_NAME bGSL:7eaa7a74-f775-4783-8650-7bf8b3914991 Idose 3B PUBDICT_GLYCONAVI_NAME bGSL:7117af95-d22c-461f-afe7-e6e7d6394f35 isomaltose 3B G36281WI PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; PUBDICT_GLYCONAVI_NAME bGSL:330b6563-5442-42fb-97e7-ee362a6e92c0 Isomaltotriose 3B PUBDICT_GLYCONAVI_NAME bGSL:0b8af6d1-e5d2-4b5b-9bc1-9d05835c36eb isopanose 3B G37117TJ PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; PUBDICT_GLYCONAVI_NAME bGSL:053c0b76-203b-4515-b9af-b7dc5823b80d Kanosamine 3B PUBDICT_GLYCONAVI_NAME bGSL:b44482c5-bba5-409b-b21f-c648dcd85b08 Kansosamine 3B PUBDICT_GLYCONAVI_NAME bGSL:f8270ee4-66b2-44ca-89e9-34568e45d5f5 Kojibiose 3B PUBDICT_GLYCONAVI_NAME bGSL:078d38fa-baf3-4bb7-94ab-192551e696cb L-Fucitol L-fucitol 3B PUBDICT_GLYCONAVI_NAME bGSL:7d6cbcfd-0ed7-4448-8873-f1c66c2d9579 lactose Lac 3B G15541SE; G84224TW PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; PUBDICT_GLYCONAVI_NAME; PUBDICT_GLYCONAVI_ABBREV bGSL:f84aaa55-48c2-4635-9e27-661ec4cd9e95 Lactosediamine 3B PUBDICT_GLYCONAVI_NAME bGSL:00adcf1f-9a31-48c8-a220-9acab620e167 Laminarabiose 3B PUBDICT_GLYCONAVI_NAME bGSL:326b663d-7684-4703-8953-8cace34d28f3 Levoglucosan 3B PUBDICT_GLYCONAVI_NAME bGSL:3fbb9745-bbab-4181-88a6-ca413ef9d3af Levoglucosenone 3B PUBDICT_GLYCONAVI_NAME bGSL:a4a200ba-f476-42f4-a7fe-05794cc535aa Lyxose 3B PUBDICT_GLYCONAVI_NAME bGSL:16398fb9-0a43-4704-a849-28dd77efb5e3 maltose 3B G44653LT PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; PUBDICT_GLYCONAVI_NAME bGSL:5a8ee470-9d6e-40b3-9f0d-9dbe77455ce6 Mannosamine 3B PUBDICT_GLYCONAVI_NAME bGSL:e6f705ff-71da-4181-9adb-2134e48c31cd Mannose Man α-linked mannose 3B G70323CJ SUGARBIND; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCONAVI_NAME bGSL:6b2282ff-98bd-5b24-ae0a-bcd11c8a87b2 Mannotriose tri-mannose / O-linked 3B G17780OR; G47395XN; G28528AG SUGARBIND; PUBDICT_GLYCONAVI_NAME bGSL:c213d93a-7a14-45f1-a3bb-5ef76ba742ea Manα1-3Man disaccharide alpha-oligomannoside 3B EOG_VARKI_4E A disaccharide consisting of two mannose residues connected by an α1-3 glycosidic bond. This structure can function as an inhibitor of mannose-binding proteins that are involved in adhesion processes. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch43/#:~:text=Glycoconjugates%20and%20GBPs%2C%20as,Teladorsagia%20circumcincta'] bGSL:b7f43e65-ca23-4fee-b60e-6ac77c35b21e Melezitose 3B PUBDICT_GLYCONAVI_NAME bGSL:aac7832b-fdd0-4486-8ed4-2876b9a04023 Melibiose 3B G86123DJ; G66481II SUGARBIND; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; PUBDICT_GLYCONAVI_NAME bGSL:51a074c2-d790-4819-bc4c-d23925d8edd6 Muramic acid 3B PUBDICT_GLYCONAVI_NAME bGSL:8481360e-a15a-47fd-b97c-4370f6d023bb Mycaminose 3B PUBDICT_GLYCONAVI_NAME bGSL:2c25dc41-f7ee-4b82-b631-02361ed4e98a Mycarose 3B PUBDICT_GLYCONAVI_NAME bGSL:cd1ddde9-da6a-4a07-816a-d51368e59009 Mycinose 3B PUBDICT_GLYCONAVI_NAME bGSL:6f86d65e-cbdf-48a7-94b2-f69ff86f7fb1 Mycosamine 3B PUBDICT_GLYCONAVI_NAME bGSL:98eba857-dab7-4543-9935-9f992c354b49 N-acetylgalactosamine N-acetyl-D-galactosamine GalNAc α(1-3)-linked N-acetylgalactosamine; terminal N-acetylgalactosamine 3B G61418DU; G27025MB; G39738WL SUGARBIND; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:0e9ac6e8-3849-4b73-adc6-1a4dcef18348 N-acetylglucosamine GlcNAc; GN terminal N-acetylglucosamine; O-GlcNac glycan; β6-linked N-acetylglucosamine 3B G64581RP SUGARBIND; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCONAVI_NAME bGSL:bf9c6886-573f-4272-8c11-62e639bf1dce N-acetylneuraminic acid Sialic acid; NANA NANA; NeuAc; Neu5Ac Neuraminic acid 9-O-acetyl sialic acid 3B G81533KY; G50850NI; G76685HR SUGARBIND; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE bGSL:3b2bd9e8-6e0f-4eea-aa60-c036194d68eb Neuraminic acid 9-O-acetyl sialic acid; N-acetylneuraminic acid 3B PUBDICT_GLYCONAVI_NAME bGSL:fd161fba-600c-40d4-aa5e-b9f91b92efd3 Nigerose 3B PUBDICT_GLYCONAVI_NAME bGSL:98644ea2-7baf-49ca-978c-8ab4260421dd Nojirimycin 3B PUBDICT_GLYCONAVI_NAME bGSL:75a65bbe-f16f-4c00-84b2-1827d830e138 Noviose 3B PUBDICT_GLYCONAVI_NAME bGSL:ba4e2242-bab8-4dbe-81ff-bb73f9268e6a O-acetylated sialic acids O-acetylated Sias O-Ac-SA 9-O-acetyl sialic acid 3B EOG_VARKI_4E Sialic acids that are modified by the addition of an O-acetyl group at one or more hydroxyl positions. These modifications can influence recognition by viral and immune receptors and are regulated by specific esterases. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch42/#:~:text=HIV%20expresses%20surface%20glycans%20that,the%20spike%20receptor%20binding%20domain', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch46/#:~:text=The%20primary%20cause%20of%20the%20disease,dialysis%20and%20open-heart%20surgery', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch15/#:~:text=However%2C%20at%20the%20whole-body%20level%2C,are%20released%20from%20host%20cells', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch15/#:~:text=Mutations%20of%20other%20STs%20in%20mice,to%20protect%20against%20microorganisms'] bGSL:b3c76c06-594d-4633-81c9-6f23910cbae8 O-linked Glc-Gal disaccharide O-Linked Glc-Gal 3B EOG_VARKI_4E A disaccharide composed of glucose and galactose that is O-linked to hydroxylysine residues, playing an important role in collagen fibril formation. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch13/#:~:text=O-mannosylation%20of%20%CE%B1-dystroglycan,in%20glycoproteins%20and%20proteoglycans'] bGSL:7110ae50-0828-4db3-9d21-42d6bde28a67 Oleandrose 3B PUBDICT_GLYCONAVI_NAME bGSL:2a32950d-7f46-4b5e-881e-624a151a3ea0 oligogalacturonides 3B EOG_VARKI_4E Oligogalacturonides are oligosaccharides consisting of linear chains of galacturonic acid residues, usually generated by the partial degradation of pectin. They play important roles in plant growth, development, and defense signaling. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch40/#:~:text=LNP%20is%20a%20peripheral%20membrane,responses%20to%20the%20hormone%20auxin', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch40/#:~:text=Many%20of%20these%20effects%20may%20result,involved%20in%20plant%20defense', 'https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch40/#:~:text=In%20this%20case%2C%20the%20released%20active,that%20are%20fragmented%20by%20chitinase'] bGSL:1cbbe4a9-2b71-4254-9991-d2acbb44129a oligoglucosides 3B EOG_VARKI_4E Oligoglucosides are oligosaccharides composed of glucose residues, often featuring 1-6 or 1-3 β-glucose linkages. They can be released from cell walls and may function as signaling molecules, such as oligosaccharins, in plant-pathogen interactions. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch40/#:~:text=The%20activities%20of%20such,oligosaccharides%20%28Figure%2040.2%29'] bGSL:e7abed1d-9c09-40e8-b4fc-130fd2513195 panose 3B G44612JM PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; PUBDICT_GLYCONAVI_NAME bGSL:b16be666-63aa-4171-9681-64703e6f31c6 Paratose 3B PUBDICT_GLYCONAVI_NAME bGSL:bbfb4002-e9e3-4ee0-b2b6-7b47ce35c18b Perosamine 3B PUBDICT_GLYCONAVI_NAME bGSL:3ca18716-e589-4fab-badd-a839dfe7da10 Planteose 3B PUBDICT_GLYCONAVI_NAME bGSL:51fe76c1-6955-42da-8df8-2ef87f767fe3 Pneumosamine 3B PUBDICT_GLYCONAVI_NAME bGSL:1dad1d72-b8b5-4694-9b9c-8387bd20169f primeverose 3B G82276DL PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; PUBDICT_GLYCONAVI_NAME bGSL:7afce477-48b2-46ce-af46-f7134cfcd09e Psicose 3B PUBDICT_GLYCONAVI_NAME bGSL:ed48a1a4-0df5-40d8-8f34-392c23580698 Purpurosamine C 3B PUBDICT_GLYCONAVI_NAME bGSL:8a83e996-9b5a-406d-bd06-d7a1698fc076 Quinovosamine 3B PUBDICT_GLYCONAVI_NAME bGSL:c1ba30b6-f290-463f-a4ba-4d951c8959c3 Quinovose 3B PUBDICT_GLYCONAVI_NAME bGSL:7f7e1659-d397-42b4-9ca2-9458d32af7a5 Rhamnitol 3B PUBDICT_GLYCONAVI_NAME bGSL:f48fcdbe-fc87-4a2b-b7ed-52b67167039b Rhamnosamine 3B PUBDICT_GLYCONAVI_NAME bGSL:4d9d37b3-2910-4ff0-9f80-5301ab251984 Rhamnose 3B PUBDICT_GLYCONAVI_NAME bGSL:8f18dd13-ca52-400f-92ce-6aa6083e6655 Rhodinose 3B PUBDICT_GLYCONAVI_NAME bGSL:3e61c7cf-337c-4e4e-8dd8-1761772761f8 Rhodosamine 3B PUBDICT_GLYCONAVI_NAME bGSL:8a3ed703-7526-4c2b-905c-a51e005a3cf4 Ribose 3B PUBDICT_GLYCONAVI_NAME bGSL:a08696c3-4852-4513-9900-4c32ea08cacd Ribulose 3B PUBDICT_GLYCONAVI_NAME bGSL:6a9ff943-05d5-4330-977a-47063bab3015 rutinose 3B G68857PG PUBDICT_GLYCOSMOS; PUBDICT_GLYCAN_IMAGE; PUBDICT_GLYCONAVI_NAME bGSL:1c08094e-1f96-4ba2-aacd-60a8dd7d0baa Sarmentose 3B PUBDICT_GLYCONAVI_NAME bGSL:89fc638d-a1b9-437c-9989-5ed22694f3d7 Sedoheptulosan 3B PUBDICT_GLYCONAVI_NAME bGSL:fa303dab-e8c1-4d6d-a525-fcfef6f97ff3 Sedoheptulose 3B PUBDICT_GLYCONAVI_NAME bGSL:d875fd6d-3f43-4f90-8d3c-c415659bcef9 Solatriose 3B PUBDICT_GLYCONAVI_NAME bGSL:1e49b13b-5812-4b64-93ea-6bfeaa9335b4 Sophorose 3B PUBDICT_GLYCONAVI_NAME bGSL:16d91f8c-34a0-4d8e-963b-76b28be704e4 Sorbose 3B PUBDICT_GLYCONAVI_NAME bGSL:62b1b32a-da6f-4e7e-ba54-fe30443f6e4c Stachyose 3B PUBDICT_GLYCONAVI_NAME bGSL:c36a4ab7-131a-4046-8c49-2b9e95671646 Streptose 3B PUBDICT_GLYCONAVI_NAME bGSL:2a485542-b766-4d47-b2ac-286a8fa6f46d Sucrose 3B PUBDICT_GLYCONAVI_NAME bGSL:308e21c0-bbb4-4c2a-afbd-91f2785fe956 Tagatose 3B PUBDICT_GLYCONAVI_NAME bGSL:d323027f-9db2-4fb3-984c-3bc6a21c9590 Talose 3B PUBDICT_GLYCONAVI_NAME bGSL:959e890e-6f12-4967-a76e-441bd1c660ae Threose 3B PUBDICT_GLYCONAVI_NAME bGSL:57beae3c-61f5-4179-b8af-97ec17077176 Trehalosamine 3B PUBDICT_GLYCONAVI_NAME bGSL:8f4676bc-4855-44f0-b411-9dfde791bb60 Turanose 3B PUBDICT_GLYCONAVI_NAME bGSL:90f0f11b-48e8-4f77-9e2f-5c4eee2dbb50 Tyvelose 3B PUBDICT_GLYCONAVI_NAME bGSL:40987927-6da6-43ce-9ed0-241a74043bf4 Umbelliferose 3B PUBDICT_GLYCONAVI_NAME bGSL:59cba7fb-79c0-4ba9-a56e-bdc37c6c01a9 Xylose 3B PUBDICT_GLYCONAVI_NAME bGSL:e18a426d-97e9-445c-866b-57bfe0a4c53f xyloside β-D-xyloside 3B EOG_VARKI_4E Xylosides are glycosides in which xylose serves as the sugar moiety. They are used experimentally to prime the synthesis and secretion of glycosaminoglycan chains in cells. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch55/#:~:text=Xylosides%20mimic%20the%20natural,disaccharides%20and%20trisaccharides'] bGSL:2bc42ba1-91ff-4836-b1cf-cba088d8c1fd Xylulose 3B PUBDICT_GLYCONAVI_NAME bGSL:ec226ca7-50cb-4b7b-971b-93712c4532f1 α,α-Trehalose 3B PUBDICT_GLYCONAVI_NAME bGSL:b9f17316-33c4-41a3-8d3b-81fca823cae8 β-D-xyloside xyloside 3B EOG_VARKI_4E A glycoside in which a β-D-xylose residue is linked to an aglycone. β-D-xylosides can alter proteoglycan biosynthesis by serving as artificial primers for glycosaminoglycan chain initiation. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch55/#:~:text=Xylosides%20mimic%20the%20natural,disaccharides%20and%20trisaccharides'] bGSL:deab8be7-23a7-434a-b935-69037d61d6b9 β-N-acetylgalactosaminide β4-linked N-acetylgalactosamine 3B EOG_VARKI_4E A glycan structure featuring an N-acetylgalactosamine residue linked through a beta-glycosidic bond. These structures can serve as primers for oligosaccharide chains on mucins and are known to inhibit O-glycosylation of glycoproteins. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch55/#:~:text=Xylosides%20mimic%20the%20natural,disaccharides%20and%20trisaccharides'] bGSL:39c7dc53-2f86-4776-8e16-0f4c2e238b64 β-N-acetylglucosaminide β2-linked N-acetylglucosamine; β6-linked N-acetylglucosamine; β4-linked N-acetylglucosamine 3B EOG_VARKI_4E A glycan structure containing an N-acetylglucosamine residue linked via a beta-glycosidic bond; it is found as an active glycoside in various oligosaccharides. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch55/#:~:text=Xylosides%20mimic%20the%20natural,disaccharides%20and%20trisaccharides'] bGSL:5e7a6393-d027-4293-8d3d-865558a3c338 As-Fibrinogen 3C BIOOLIGO bGSL:9cd8ee71-7ee6-4663-ac7e-a61c73bcaa12 asialo-, agalacto-N-glycan from porcine fibrinogen 3C BIOOLIGO bGSL:9bb31a83-06d7-4f9f-9c93-75d234559874 Aspergillus fumigatus GPI oligosaccharide 3C EOG_VARKI_4E This is a glycosylphosphoceramide structure identified in Aspergillus fumigatus, featuring a galactomannan chain with a defined mannosylated core (Manα1-2Manα1-2Manα1-6Manα1-4GlcN) that is directly linked to inositolphosphoceramide, notably lacking a bridging phosphoethanolamine. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch12/#:~:text=fumigatus,%282-AB%29%20by%20reductive%20amination'] bGSL:3b3f5e74-ff30-4522-9647-46704d6a52b7 di-sialylated N-glycan from porcine fibrinogen 3C BIOOLIGO bGSL:bb09cb8a-2e4c-4863-a813-b85269aa0360 GPI anchor 3C G46392BZ; G00045MO GlycoMotif:GGM.001030 GLYCOMOTIF_GGM; PUBDICT_MOTIF_GTC; BIOOLIGO TRUE bGSL:f23e64b6-c095-469e-a6aa-747385bc4e56 HNK-expressing SGLPG NHK-1-expressing sulfoglucuronyl-lactosaminyl-paragloboside 3C G43040ZY; G10503MP GlycoMotif:CCRC.000129; GlycoMotif:GDV.000080 CUMMINGS; GLYCOMOTIF_CCRC; GLYCOMOTIF_GDV; PUBDICT_GLYCAN_MOTIF bGSL:d94e395b-fd29-4e98-9ca7-cd2901029849 Human milk oligosaccharide Milk Sugar Core HMO 3C G15541SE GlycoMotif:GGM.001029 GLYCOMOTIF_GGM bGSL:44dc45fb-286a-4d03-bbd4-71137ef26009 Leishmania lipophosphoglycan repeat unit 3C EOG_VARKI_4E A repeating disaccharide-phosphate unit composed of galactose (β1-4 linked to mannose) with a phosphate group, forming the backbone of the phosphoglycan polymer in Leishmania lipophosphoglycan (LPG) and related phosphoglycosylated protein glycans. This structural motif is characteristic of the phosphoglycan portions of LPG and proteophosphoglycan (PPG) in certain protozoa. ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch43/#:~:text=The%20basic%20LPG%20structure%20in%20all,parasite%20from%20the%20sandfly%20midgut'] ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch43/#:~:text=LPG%20is%20highly%20abundant%20on%20the,via%20unique%20phosphodiester%20linkages'] ['https://www.ncbi.nlm.nih.gov/books/n/glyco4/ch43/#:~:text=The%20phosphoglycan%20portions%20of%20LPG,to%20infection%20and%20cell%20signaling'] bGSL:a9899b3f-f129-476f-b4ba-41ae8f9ba948 Leukocyte common antigen LCA LCA; CD45 3C G78436BB; G50850NI SUGARBIND; PUBDICT_GLYCAN_MOTIF bGSL:bffec5bf-26bc-49af-9fa4-19abbb1e94d2 Leukosialin Sialophorin; SPN; Sialophorin and SPN SPN; CD43 3C G78436BB; G50850NI SUGARBIND; PUBDICT_GLYCAN_MOTIF bGSL:a0d415f4-b0e2-4b8c-a0a5-a8acba0eb848 Mono-sialylated N-glycan from porcine fibrinogen 3C BIOOLIGO bGSL:aae87e47-879b-464b-9fd6-43f465b8b4e9 nonfucosylated triantennary N-glycan triantennary complex-type N-glycan; triantennary N-glycan; trisialylated triantennary N-glycan 3C GSD:00116 GSD_GLYGEN_V1 A triantennary N-linked glycan with three GlcNAc branches linked to the core and no fucose appears. Carbohydrate structures of human alpha-fetoprotein of patients with hepatocellular carcinoma: presence of fucosylated and non-fucosylated triantennary glycans.[PMID:7679920] bGSL:cd16c191-eaec-4f51-95f9-7f3208f79da5 O-fucose glycan /EGF Repeat O-fucose glycan 3C G17931GP; G39294YF GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCAN_IMAGE bGSL:4c30e1e2-c76a-44bd-ad6d-656091ef6dea O-fucose glycan /Thrombospondin Type 1 Repeat O-fucose core O-fucose glycan Glcβ1-3Fucα-O- 3C G36855WW GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCAN_IMAGE bGSL:db8504e5-852f-4583-a208-bb2f5cecddbc O-GlcNAc Core EGF Type 3C G66213AR GlycoMotif:GGM.001040 GLYCOMOTIF_GGM bGSL:1f59a0f1-4427-4685-af8d-84af030db143 O-mannose glycan / mammalian O-Mannosyl Glycan / Mammalian O-mannose glycan O-mannose core M3; O-mannose core M1; O-mannose core M2 3C G41959YC; G59126YU GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCAN_IMAGE bGSL:109006b7-6bf9-473b-a269-d604805141dc O-mannose glycan / yeast O-Mannosyl Glycan / Yeast O-mannose glycan tri-mannose / O-linked 3C G25559RS; G63072CF GLYCOEPITOPE; PUBDICT_GLYCAN_MOTIF; PUBDICT_GLYCAN_IMAGE bGSL:bd1beec7-8c58-401d-89cb-3ccdbed086a5 tri-sialylated N-glycan from porcine fibrinogen 3C BIOOLIGO