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{"_id":{"$oid":"5e1df99fb8171e1b5dab2860"},"query":{"execution_time":"2020-01-14 12:25:51 EST-0500","glytoucan_ac":"G36191CD","organism":{"id":9606,"name":"Homo sapiens"}},"results":[{"uniprot_canonical_ac":"Q9BT22-1","gene_link":"https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=18294","protein_name":"Chitobiosyldiphosphodolichol beta-mannosyltransferase","chromosome":"16","start_pos":5084878,"end_pos":5071850,"organism":"Homo sapiens","gene_name":"ALG1","tax_id":9606},{"uniprot_canonical_ac":"Q9NP73-1","gene_link":"https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=30881","protein_name":"Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13","chromosome":"X","start_pos":111759996,"end_pos":111681219,"organism":"Homo sapiens","gene_name":"ALG13","tax_id":9606},{"uniprot_canonical_ac":"Q96F25-1","gene_link":"https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=28287","protein_name":"UDP-N-acetylglucosamine transferase subunit ALG14 homolog","chromosome":"1","start_pos":95072898,"end_pos":94983079,"organism":"Homo sapiens","gene_name":"ALG14","tax_id":9606},{"uniprot_canonical_ac":"Q9H553-1","gene_link":"https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=23159","protein_name":"Alpha-1,3/1,6-mannosyltransferase ALG2","chromosome":"9","start_pos":99221894,"end_pos":99217937,"organism":"Homo sapiens","gene_name":"ALG2","tax_id":9606},{"uniprot_canonical_ac":"P15291-1","gene_link":"https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=924","protein_name":"Beta-1,4-galactosyltransferase 1","chromosome":"9","start_pos":33167169,"end_pos":33113457,"organism":"Homo sapiens","gene_name":"B4GALT1","tax_id":9606},{"uniprot_canonical_ac":"O60909-1","gene_link":"https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=925","protein_name":"Beta-1,4-galactosyltransferase 2","chromosome":"1","start_pos":43990445,"end_pos":43981161,"organism":"Homo sapiens","gene_name":"B4GALT2","tax_id":9606},{"uniprot_canonical_ac":"O60512-1","gene_link":"https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=926","protein_name":"Beta-1,4-galactosyltransferase 3","chromosome":"1","start_pos":161176060,"end_pos":161171819,"organism":"Homo sapiens","gene_name":"B4GALT3","tax_id":9606},{"uniprot_canonical_ac":"Q9H3H5-1","gene_link":"https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=2995","protein_name":"UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase","chromosome":"11","start_pos":119101655,"end_pos":119097001,"organism":"Homo sapiens","gene_name":"DPAGT1","tax_id":9606},{"uniprot_canonical_ac":"P26572-1","gene_link":"https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=7044","protein_name":"Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase","chromosome":"5","start_pos":180792971,"end_pos":180791637,"organism":"Homo sapiens","gene_name":"MGAT1","tax_id":9606},{"uniprot_canonical_ac":"Q10469-1","gene_link":"https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=7045","protein_name":"Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase","chromosome":"14","start_pos":49622609,"end_pos":49621269,"organism":"Homo sapiens","gene_name":"MGAT2","tax_id":9606}],"list_id":"f134cd9e1be1e02da3807aefabc8b2a4"}
{"_id":{"$oid":"5ee3939fb8171e44324232a9"},"query":{"execution_time":"2020-06-12 10:39:27 EDT-0400","glytoucan_ac":"G17689DH","organism":{"id":0,"name":"All"}},"results":[{"uniprot_canonical_ac":"P27808-1","gene_link":"https://www.uniprot.org/uniprot/P27808","protein_name":"Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase; 2.4.1.101; N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I; GNT-I; GlcNAc-T I","chromosome":"11","start_pos":49262032,"end_pos":49260692,"organism":"Mus musculus","gene_name":"Mgat1; Gnt1; Mgat-1","tax_id":10090},{"uniprot_canonical_ac":"Q9NP73-1","gene_link":"https://www.uniprot.org/uniprot/Q9NP73","protein_name":"Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13; 2.4.1.141; 3.4.19.12; Asparagine-linked glycosylation 13 homolog; Glycosyltransferase 28 domain-containing protein 1; UDP-N-acetylglucosamine transferase subunit ALG13 homolog","chromosome":"X","start_pos":111759996,"end_pos":111681219,"organism":"Homo sapiens","gene_name":"CDG1S; CXorf45; EIEE36; GLT28D1; MDS031; TDRD13; YGL047W; CXorf45; ALG13; MDS031; GLT28D1","tax_id":9606},{"uniprot_canonical_ac":"Q9Z2Y2-1","gene_link":"https://www.uniprot.org/uniprot/Q9Z2Y2","protein_name":"Beta-1,4-galactosyltransferase 2; Beta-1,4-GalTase 2; 2.4.1.-; Beta4Gal-T2; b4Gal-T2; Nal synthase; UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 2; UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 2; Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase; 2.4.1.38; Lactose synthase A protein; 2.4.1.22; N-acetyllactosamine synthase; 2.4.1.90; Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase","chromosome":"4","start_pos":117881618,"end_pos":117873856,"organism":"Mus musculus","gene_name":"Ggtb2; B4galt2","tax_id":10090},{"uniprot_canonical_ac":"Q9D081-1","gene_link":"https://www.uniprot.org/uniprot/Q9D081","protein_name":"UDP-N-acetylglucosamine transferase subunit ALG14 homolog","chromosome":"3","start_pos":121361783,"end_pos":121291848,"organism":"Mus musculus","gene_name":"5430428G01Rik; 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DPAGT1; ALG7; CDG-Ij; CDG1J; CMS13; CMSTA2; D11S366; DGPT; DPAGT; DPAGT2; G1PT; GPT; UAGT; UGAT","tax_id":9606},{"uniprot_canonical_ac":"Q10469-1","gene_link":"https://www.uniprot.org/uniprot/Q10469","protein_name":"Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase; 2.4.1.143; GlcNAc-T II; GNT-II; Beta-1,2-N-acetylglucosaminyltransferase II; N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase II; Mannoside acetylglucosaminyltransferase 2","chromosome":"14","start_pos":49622609,"end_pos":49621269,"organism":"Homo sapiens","gene_name":"MGAT2; CDG2A; CDGS2; GLCNACTII; GNT-II; GNT2","tax_id":9606},{"uniprot_canonical_ac":"Q11203-1","gene_link":"https://www.uniprot.org/uniprot/Q11203","protein_name":"CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase; 2.4.99.6; Beta-galactoside alpha-2,3-sialyltransferase 3; Alpha 2,3-ST 3; ST3Gal III; ST3GalIII; Sialyltransferase 6; Gal beta-1,3(4) GlcNAc alpha-2,3 sialyltransferase; ST3N; N-acetyllactosaminide alpha-2,3-sialyltransferase","chromosome":"1","start_pos":43930218,"end_pos":43736263,"organism":"Homo sapiens","gene_name":"ST3GAL3; 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CDGF1; FUT8","tax_id":9606},{"uniprot_canonical_ac":"Q96F25-1","gene_link":"https://www.uniprot.org/uniprot/Q96F25","protein_name":"UDP-N-acetylglucosamine transferase subunit ALG14 homolog","chromosome":"1","start_pos":95072898,"end_pos":94983079,"organism":"Homo sapiens","gene_name":"CMS15; ALG14","tax_id":9606},{"uniprot_canonical_ac":"Q8BML3-1","gene_link":"https://www.uniprot.org/uniprot/Q8BML3","protein_name":"MCG145726; Glycosyltransferase 28 domain-containing 2","chromosome":"3","start_pos":85872164,"end_pos":85871670,"organism":"Mus musculus","gene_name":"4732486J07Rik; Glt28d1l; Glt28d2; mCG_145726","tax_id":10090},{"uniprot_canonical_ac":"Q921V5-1","gene_link":"https://www.uniprot.org/uniprot/Q921V5","protein_name":"Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase; 2.4.1.143; GlcNAc-T II; GNT-II; Beta-1,2-N-acetylglucosaminyltransferase II; N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase II; Mannoside acetylglucosaminyltransferase 2","chromosome":"12","start_pos":69185979,"end_pos":69184654,"organism":"Mus musculus","gene_name":"Mgat2; AA407964; CDGS2; GLCNACTII; GNT-II; GNT2","tax_id":10090},{"uniprot_canonical_ac":"Q11206-1","gene_link":"https://www.uniprot.org/uniprot/Q11206","protein_name":"CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4; Alpha 2,3-ST 4; 2.4.99.2; Beta-galactoside alpha-2,3-sialyltransferase 4; 2.4.99.4; Sialyltransferase 4C; SIAT4-C; ST3Gal IV; ST3GalIV; STZ; ST-4; ST3GalA.2; Alpha 2,3-sialyltransferase IV; Gal-beta-1,4-GalNAc-alpha-2,3-sialyltransferase; SAT-3; Gal-NAc6S","chromosome":"11","start_pos":126414044,"end_pos":126406156,"organism":"Homo sapiens","gene_name":"CGS23; gal-NAc6S; NANTA3; SAT3; SIAT4; SIAT4C; ST-4; ST3GalA.2; ST3GalIV; STZ; SIAT4C; ST3GAL4; NANTA3; CGS23; STZ","tax_id":9606},{"uniprot_canonical_ac":"Q921Q3-1","gene_link":"https://www.uniprot.org/uniprot/Q921Q3","protein_name":"Chitobiosyldiphosphodolichol beta-mannosyltransferase; 2.4.1.142; Beta-1,4-mannosyltransferase; Asparagine-linked glycosylation protein 1 homolog; GDP-Man:GlcNAc2-PP-dolichol mannosyltransferase; GDP-mannose-dolichol diphosphochitobiose mannosyltransferase","chromosome":"16","start_pos":5244623,"end_pos":5233650,"organism":"Mus musculus","gene_name":"Alg1; HMAT1; HMT1","tax_id":10090},{"uniprot_canonical_ac":"P26572-1","gene_link":"https://www.uniprot.org/uniprot/P26572","protein_name":"Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase; 2.4.1.101; N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I; GNT-I; GlcNAc-T I","chromosome":"5","start_pos":180792971,"end_pos":180791637,"organism":"Homo sapiens","gene_name":"GGNT1; GLCT1; MGAT1; GLYT1; MGAT; GLCNAC-TI; GLCT1; GLYT1; GNT-1; GNT-I; GnTI; MGAT","tax_id":9606},{"uniprot_canonical_ac":"Q9BT22-1","gene_link":"https://www.uniprot.org/uniprot/Q9BT22","protein_name":"Chitobiosyldiphosphodolichol beta-mannosyltransferase; 2.4.1.142; Mannosyltransferase-1; MT-1; hMat-1; Beta-1,4-mannosyltransferase; Asparagine-linked glycosylation protein 1 homolog; GDP-Man:GlcNAc2-PP-dolichol mannosyltransferase; GDP-mannose-dolichol diphosphochitobiose mannosyltransferase","chromosome":"16","start_pos":5084878,"end_pos":5071850,"organism":"Homo sapiens","gene_name":"ALG1; PRO1870; HMT1; PSEC0061; HMAT1; CDG1K; hMat-1; HMAT1; HMT-1; HMT1; Mat-1; MT-1","tax_id":9606},{"uniprot_canonical_ac":"Q9H553-1","gene_link":"https://www.uniprot.org/uniprot/Q9H553","protein_name":"Alpha-1,3/1,6-mannosyltransferase ALG2; 2.4.1.132; 2.4.1.257; GDP-Man:Man(2)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase; GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase; Asparagine-linked glycosylation protein 2 homolog; GDP-Man:Man(1)GlcNAc(2)-PP-dolichol mannosyltransferase","chromosome":"9","start_pos":99221894,"end_pos":99217937,"organism":"Homo sapiens","gene_name":"ALG2; PRO1298; CDG1I; CDGIi; CMS14; CMSTA3; hALPG2; NET38","tax_id":9606},{"uniprot_canonical_ac":"O60512-1","gene_link":"https://www.uniprot.org/uniprot/O60512","protein_name":"Beta-1,4-galactosyltransferase 3; Beta-1,4-GalTase 3; 2.4.1.-; Beta4Gal-T3; b4Gal-T3; UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 3; Nal synthase; UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 3; Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase; 2.4.1.38; N-acetyllactosamine synthase; 2.4.1.90; Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase","chromosome":"1","start_pos":161176060,"end_pos":161171819,"organism":"Homo sapiens","gene_name":"B4GALT3; beta4Gal-T3","tax_id":9606},{"uniprot_canonical_ac":"P15291-1","gene_link":"https://www.uniprot.org/uniprot/P15291","protein_name":"Beta-1,4-galactosyltransferase 1; Beta-1,4-GalTase 1; 2.4.1.-; Beta4Gal-T1; b4Gal-T1; UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 1; UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 1; Nal synthase; Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase; 2.4.1.38; Lactose synthase A protein; 2.4.1.22; N-acetyllactosamine synthase; 2.4.1.90; Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase","chromosome":"9","start_pos":33167169,"end_pos":33113457,"organism":"Homo sapiens","gene_name":"B4GALT1; GGTB2; B4GAL-T1; beta4Gal-T1; CDG2D; GGTB2; GT1; GTB","tax_id":9606},{"uniprot_canonical_ac":"Q9D8C3-1","gene_link":"https://www.uniprot.org/uniprot/Q9D8C3","protein_name":"Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13; 2.4.1.141; 3.4.19.12; Asparagine-linked glycosylation 13 homolog; Glycosyltransferase 28 domain-containing protein 1; UDP-N-acetylglucosamine transferase subunit ALG13 homolog","chromosome":"N/A","start_pos":0,"end_pos":0,"organism":"Mus musculus","gene_name":"Alg13; 2810046O15Rik; 4833435D08Rik; Glt28d1; MDS031; Glt28d1","tax_id":10090},{"uniprot_canonical_ac":"Q91YY2-1","gene_link":"https://www.uniprot.org/uniprot/Q91YY2","protein_name":"Beta-1,4-galactosyltransferase 3; Beta-1,4-GalTase 3; 2.4.1.-; Beta4Gal-T3; b4Gal-T3; UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 3; Nal synthase; UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 3; Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase; 2.4.1.38; N-acetyllactosamine synthase; 2.4.1.90; Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase","chromosome":"1","start_pos":171276376,"end_pos":171271743,"organism":"Mus musculus","gene_name":"B4galt3; 9530061M23Rik; AA104562; AW125175; ESTM26; ESTM6; R74981","tax_id":10090},{"uniprot_canonical_ac":"O60909-1","gene_link":"https://www.uniprot.org/uniprot/O60909","protein_name":"Beta-1,4-galactosyltransferase 2; Beta-1,4-GalTase 2; 2.4.1.-; Beta4Gal-T2; b4Gal-T2; Nal synthase; UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 2; UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 2; Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase; 2.4.1.38; Lactose synthase A protein; 2.4.1.22; N-acetyllactosamine synthase; 2.4.1.90; Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase","chromosome":"1","start_pos":43990445,"end_pos":43981161,"organism":"Homo sapiens","gene_name":"B4Gal-T2; B4Gal-T3; beta4Gal-T2; B4GALT2","tax_id":9606}],"list_id":"15dd9e3e1e0c598bb451a52be9ef140e"}
{"_id":{"$oid":"5fa0aed7b8171e299c503e70"},"query":{"execution_time":"2020-11-02 20:13:59 EST-0500","glytoucan_ac":"G00800WJ","organism":{"id":9606,"name":"Homo sapiens"}},"results":[{"function":"Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans., [UniProtKB]; We also demonstrated that overexpression of FUT8 might be responsible for the decreased PSA expression in prostate cancer specimens. To our knowledge, this is the first study reporting the functional role of fucosylated enzyme in the development of castration-resistant prostate cancer., [RefSeq]; Expression in relation to p53 is a prognostic biomarker for patients with stage II and III colorectal cancer Publication Status: Online-Only, [RefSeq]; Expression of FUT8 is regulated by three different promoters, starting transcription in exons A, B, or C., [RefSeq]; Our results reveal a positive feedback mechanism of FUT8-mediated receptor core fucosylation that promotes TGF-b signaling and EMT, thus stimulating breast cancer cell invasion and metastasis. Publication Status: Online-Only, [RefSeq]; Loss of function mutations in FUT8 cause a congenital disorder of glycosylation (FUT8-CDG) characterized by defective core fucosylation., [RefSeq]","uniprot_canonical_ac":"Q9BYC5-1","publication_count":12,"reported_o_glycosites_with_glycan":0,"protein_name":"Alpha-(1,6)-fucosyltransferase","protein_names_uniprotkb":"Alpha-(1,6)-fucosyltransferase; Fucosyltransferase 8; GDP-fucose--glycoprotein fucosyltransferase; 2.4.1.68; Glycoprotein 6-alpha-L-fucosyltransferase; Alpha1-6FucT; GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase","gene_names_refseq":"FUT8; CDGF; CDGF1","refseq_ac":"NP_004471.4","protein_names_refseq":"glycoprotein 6-alpha-L-fucosyltransferase; GDP-fucose--glycoprotein fucosyltransferase; GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase; alpha1-6FucT; alpha-(1,6)-fucosyltransferase; fucosyltransferase 8 (alpha (1,6) fucosyltransferase); alpha-(1,6)-fucosyltransferase isoform b","disease":"congenital disorder of glycosylation with defective fucosylation (MONDO:MONDO:0060720)","reported_n_glycosites":0,"mass":66516.0,"refseq_name":"alpha-(1,6)-fucosyltransferase isoform b","reported_n_glycosites_with_glycan":0,"reported_o_glycosites":0,"predicted_glycosites":0,"tax_id":9606,"organism":"Homo sapiens","pathway":"Reactions specific to the complex N-glycan synthesis pathway (R-HSA-975578);  (hsa:2530)","gene_name":"FUT8","gene_names_uniprotkb":"FUT8"},{"function":"Catalyzes the initial step of dolichol-linked oligosaccharide biosynthesis in N-linked protein glycosylation pathway: transfers GlcNAc-1-P from UDP-GlcNAc onto the carrier lipid dolichyl phosphate (P-dolichol), yielding GlcNAc-P-P-dolichol., [UniProtKB]; Data suggest that N-acetylglucosaminyl 1-phosphate transferase is a breast cancer therapeutic target., [RefSeq]; Present work improves our knowledge of DPAGT1-CDG and provides bases for developing tailored splicing and folding therapies Publication Status: Online-Only, [RefSeq]; We studied serum asialotransferrin (2009), which revealed a type 1 pattern compatible with type 1 glycosylation. Diagnosis of DPAGT1-CDG was confirmed by massive sequencing, which identified 2 mutations: c.329T\u003eC (p.Phe110Ser, which had not previously been described), and c.902G\u003eA (p.Arg301His) in the DPAGT1 gene., [RefSeq]","uniprot_canonical_ac":"Q9H3H5-1","publication_count":11,"reported_o_glycosites_with_glycan":1,"protein_name":"UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase","protein_names_uniprotkb":"UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase; N-acetylglucosamine-1-phosphate transferase; 2.7.8.15; GPT; GlcNAc-1-P transferase; G1PT","gene_names_refseq":"DPAGT1; ALG7; CDG-Ij; CDG1J; CMS13; CMSTA2; D11S366; DGPT; DPAGT; DPAGT2; G1PT; GPT; UAGT; UGAT","refseq_ac":"NP_001373.2","protein_names_refseq":"UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase; UDP-GlcNAc:dolichyl-phosphate N-acetylglucosaminephosphotransferase; N-acetylglucosamine-1-phosphate transferase; GlcNAc-1-P transferase 1; dolichyl-phosphate alpha-N-acetylglucosaminyltransferase; dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P tra; dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase); UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase 1","disease":"congenital disorder of glycosylation Ij (Disease Ontology:DOID:0080562); congenital myasthenic syndrome 13 (Disease Ontology:DOID:0110676)","reported_n_glycosites":0,"mass":46090.0,"refseq_name":"UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase","reported_n_glycosites_with_glycan":0,"reported_o_glycosites":0,"predicted_glycosites":1,"tax_id":9606,"organism":"Homo sapiens","pathway":"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (R-HSA-446193);  (hsa:1798); Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2 (R-HSA-4549356)","gene_name":"DPAGT1","gene_names_uniprotkb":"DPAGT1; DPAGT2"},{"function":"May be involved in protein N-glycosylation, second step of the dolichol-linked oligosaccharide pathway., [UniProtKB]; ALG13 and ALG14 form a functional endoplasmic reticulum UDP-N-acetylglucosamine transferase, [RefSeq]; A female patient heterozygous for ALG13 Asn107Ser variant presented with infantile spasms, developmental delay, and dysmorphic features.  The patient showed normal pattern of glycosylated transferrin and random pattern of X-inactivation. Review article, [RefSeq]; We report on a novel missense variant in the ALG13 gene in a nonconsanguineous Arab family that co-segregates with nonsyndromic intellectual disability., [RefSeq]; Possible multifunctional enzyme with both glycosyltransferase and deubiquitinase activities., [UniProtKB]; ALG13-is2 could be an important modifier of renal filtration defects, [RefSeq]","uniprot_canonical_ac":"Q9NP73-1","publication_count":13,"reported_o_glycosites_with_glycan":1,"protein_name":"Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13","protein_names_uniprotkb":"Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13; Glycosyltransferase 28 domain-containing protein 1; Asparagine-linked glycosylation 13 homolog; 3.4.19.12; 2.4.1.141; UDP-N-acetylglucosamine transferase subunit ALG13 homolog","gene_names_refseq":"CDG1S; CXorf45; EIEE36; GLT28D1; MDS031; TDRD13; YGL047W; ALG13","refseq_ac":"NP_001034299.3","protein_names_refseq":"putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13 isoform 3; hematopoietic stem/progenitor cells protein MDS031; UDP-N-acetylglucosamine transferase subunit ALG13 homolog; glycosyltransferase 28 domain-containing protein 1; tudor domain containing 13; asparagine-linked glycosylation 13 homolog; N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase; putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13","disease":"early infantile epileptic encephalopathy 36 (Disease Ontology:DOID:0080470)","reported_n_glycosites":0,"mass":126056.0,"refseq_name":"putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13 isoform 3","reported_n_glycosites_with_glycan":0,"reported_o_glycosites":0,"predicted_glycosites":0,"tax_id":9606,"organism":"Homo sapiens","pathway":"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (R-HSA-446193);  (hsa:79868); Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS) (R-HSA-5633231)","gene_name":"ALG13","gene_names_uniprotkb":"ALG13; GLT28D1; MDS031; CXorf45"},{"function":"Study presents molecular, clinical and biochemical findings in the largest collection of ALG1-CDG cases ever reported at a single time with 39 cases, bringing the total number to 57. This ranks it the third most common CDG type behind PMM2-CDG and ALG6-CDG. In addition, highly lethal genotype were identified and confirm the presence of a unique xeno-tetrasaccharide in ALG1-CDG patients., [RefSeq]; Participates in the formation of the lipid-linked precursor oligosaccharide for N-glycosylation. Involved in assembling the dolichol-pyrophosphate-GlcNAc(2)-Man(5) intermediate on the cytoplasmic surface of the ER., [UniProtKB]; Family study defining the phenotype of deficiency of beta-1,4 mannosyltransferase (MT-1) congenital disorder of glycosylation (CDG), due to ALG1 gene mutations. Four novel ALG1 mutations were identified., [RefSeq]; Was detected in the patient's ALG1-coding sequence., [RefSeq]; Evaluated the genetic association of WDR3 and ALG1 in schizophrenia. We examined 21 single nucleotide polymorphisms [SNPs; W1 (rs1812607)-W16 (rs6656360), A1 (rs8053916)-A10 (rs9673733)] from these genes using the Japanese case-control sample (1,808 schizophrenics and 2,170 matched controls). No significant genetic associations of these SNPs were identified. However, we detected a significant association of W4 (rs319471) Publication Status: Online-Only, [RefSeq]","uniprot_canonical_ac":"Q9BT22-1","publication_count":13,"reported_o_glycosites_with_glycan":1,"protein_name":"Chitobiosyldiphosphodolichol beta-mannosyltransferase","protein_names_uniprotkb":"Chitobiosyldiphosphodolichol beta-mannosyltransferase; GDP-Man:GlcNAc2-PP-dolichol mannosyltransferase; 2.4.1.142; Asparagine-linked glycosylation protein 1 homolog; GDP-mannose-dolichol diphosphochitobiose mannosyltransferase; hMat-1; Beta-1,4-mannosyltransferase; MT-1; Mannosyltransferase-1","gene_names_refseq":"CDG1K; hMat-1; HMAT1; HMT-1; HMT1; Mat-1; MT-1; ALG1","refseq_ac":"NP_001317433.1","protein_names_refseq":"chitobiosyldiphosphodolichol beta-mannosyltransferase isoform 2; asparagine-linked glycosylation 1 homolog (yeast, beta-1,4-mannosyltransferase); chitobiosyldiphosphodolichol beta-mannosyltransferase; GDP-mannose-dolichol diphosphochitobiose mannosyltransferase; GDP-Man:GlcNAc2-PP-dolichol mannosyltransferase; mannosyltransferase-1; asparagine-linked glycosylation protein 1 homolog; asparagine-linked glycosylation 1, beta-1,4-mannosyltransferase homolog","disease":"congenital disorder of glycosylation Ik (Disease Ontology:DOID:0080563)","reported_n_glycosites":0,"mass":52518.0,"refseq_name":"chitobiosyldiphosphodolichol beta-mannosyltransferase isoform 2","reported_n_glycosites_with_glycan":0,"reported_o_glycosites":0,"predicted_glycosites":0,"tax_id":9606,"organism":"Homo sapiens","pathway":"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (R-HSA-446193); Defective ALG1 causes ALG1-CDG (CDG-1k) (R-HSA-4549380);  (hsa:56052)","gene_name":"ALG1","gene_names_uniprotkb":"ALG1; PSEC0061; PRO1870; HMAT1; HMT1"},{"function":"ALG13 and ALG14 form a functional endoplasmic reticulum UDP-N-acetylglucosamine transferase, [RefSeq]; May be involved in protein N-glycosylation. May play a role in the second step of the dolichol-linked oligosaccharide pathway. May anchor the catalytic subunit ALG13 to the ER., [UniProtKB]; New ALG14 congenital disorder of glycosylation with early and lethal neurodegeneration with myasthenic and myopathic features., [RefSeq]; We identify ALG14 and ALG2 as novel genes in which mutations cause a congenital myasthenic syndrome, [RefSeq]","uniprot_canonical_ac":"Q96F25-1","publication_count":3,"reported_o_glycosites_with_glycan":0,"protein_name":"UDP-N-acetylglucosamine transferase subunit ALG14 homolog","protein_names_uniprotkb":"UDP-N-acetylglucosamine transferase subunit ALG14 homolog","gene_names_refseq":"CMS15; ALG14","refseq_ac":"NP_001292171.1","protein_names_refseq":"UDP-N-acetylglucosamine transferase subunit ALG14 homolog; UDP-N-acetylglucosamine transferase subunit ALG14 homolog isoform 2","disease":"congenital myasthenic syndrome 15 (Disease Ontology:DOID:0110658)","reported_n_glycosites":0,"mass":24151.0,"refseq_name":"UDP-N-acetylglucosamine transferase subunit ALG14 homolog isoform 2","reported_n_glycosites_with_glycan":0,"reported_o_glycosites":0,"predicted_glycosites":0,"tax_id":9606,"organism":"Homo sapiens","pathway":" (hsa:199857); Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS) (R-HSA-5633231); Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (R-HSA-446193)","gene_name":"ALG14","gene_names_uniprotkb":"ALG14"}],"list_id":"405aad61c54381eb9669ccc68993a3d6"}
{"_id":{"$oid":"5fa0af59b8171e2e8395fb4c"},"query":{"execution_time":"2020-11-02 20:16:09 EST-0500","glytoucan_ac":"G00318AV","organism":{"id":9606,"name":"Homo sapiens"}},"results":[{"function":"May be involved in protein N-glycosylation, second step of the dolichol-linked oligosaccharide pathway., [UniProtKB]; ALG13 and ALG14 form a functional endoplasmic reticulum UDP-N-acetylglucosamine transferase, [RefSeq]; A female patient heterozygous for ALG13 Asn107Ser variant presented with infantile spasms, developmental delay, and dysmorphic features.  The patient showed normal pattern of glycosylated transferrin and random pattern of X-inactivation. Review article, [RefSeq]; We report on a novel missense variant in the ALG13 gene in a nonconsanguineous Arab family that co-segregates with nonsyndromic intellectual disability., [RefSeq]; Possible multifunctional enzyme with both glycosyltransferase and deubiquitinase activities., [UniProtKB]; ALG13-is2 could be an important modifier of renal filtration defects, [RefSeq]","uniprot_canonical_ac":"Q9NP73-1","publication_count":13,"reported_o_glycosites_with_glycan":1,"protein_name":"Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13","protein_names_uniprotkb":"Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13; Glycosyltransferase 28 domain-containing protein 1; Asparagine-linked glycosylation 13 homolog; 3.4.19.12; 2.4.1.141; UDP-N-acetylglucosamine transferase subunit ALG13 homolog","gene_names_refseq":"CDG1S; CXorf45; EIEE36; GLT28D1; MDS031; TDRD13; YGL047W; ALG13","refseq_ac":"NP_001034299.3","protein_names_refseq":"putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13 isoform 3; hematopoietic stem/progenitor cells protein MDS031; UDP-N-acetylglucosamine transferase subunit ALG13 homolog; glycosyltransferase 28 domain-containing protein 1; tudor domain containing 13; asparagine-linked glycosylation 13 homolog; N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase; putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13","disease":"early infantile epileptic encephalopathy 36 (Disease Ontology:DOID:0080470)","reported_n_glycosites":0,"mass":126056.0,"refseq_name":"putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13 isoform 3","reported_n_glycosites_with_glycan":0,"reported_o_glycosites":0,"predicted_glycosites":0,"tax_id":9606,"organism":"Homo sapiens","pathway":"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (R-HSA-446193);  (hsa:79868); Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS) (R-HSA-5633231)","gene_name":"ALG13","gene_names_uniprotkb":"ALG13; GLT28D1; MDS031; CXorf45"},{"function":"Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate., [UniProtKB]; We identify ALG14 and ALG2 as novel genes in which mutations cause a congenital myasthenic syndrome, [RefSeq]","uniprot_canonical_ac":"Q9H553-1","publication_count":4,"reported_o_glycosites_with_glycan":0,"protein_name":"Alpha-1,3/1,6-mannosyltransferase ALG2","protein_names_uniprotkb":"Alpha-1,3/1,6-mannosyltransferase ALG2; Asparagine-linked glycosylation protein 2 homolog; 2.4.1.132; 2.4.1.257; GDP-Man:Man(1)GlcNAc(2)-PP-dolichol mannosyltransferase; GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase; GDP-Man:Man(2)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase","gene_names_refseq":"ALG2; CDG1I; CDGIi; CMS14; CMSTA3; hALPG2; NET38","refseq_ac":"NP_149078.1","protein_names_refseq":"GDP-Man:Man(1)GlcNAc(2)-PP-dolichol mannosyltransferase; homolog of yeast ALG2; GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase; asparagine-linked glycosylation 2 homolog (yeast, alpha-1,3-mannosyltransferase); asparagine-linked glycosylation 2 homolog (S. cerevisiae, alpha-1,3-mannosyltransferase); alpha-1,3-mannosyltransferase ALG2; asparagine-linked glycosylation protein 2 homolog; GDP-Man:Man(2)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase; asparagine-linked glycosylation 2, alpha-1,3-mannosyltransferase homolog; alpha-1,3/1,6-mannosyltransferase ALG2","disease":"congenital myasthenic syndrome 14 (Disease Ontology:DOID:0110669); congenital disorder of glycosylation Ii (Disease Ontology:DOID:0080561)","reported_n_glycosites":0,"mass":47092.0,"refseq_name":"alpha-1,3/1,6-mannosyltransferase ALG2","reported_n_glycosites_with_glycan":0,"reported_o_glycosites":0,"predicted_glycosites":0,"tax_id":9606,"organism":"Homo sapiens","pathway":" (hsa:85365); Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (R-HSA-446193); Defective ALG2 causes ALG2-CDG (CDG-1i) (R-HSA-4549349)","gene_name":"ALG2","gene_names_uniprotkb":"ALG2; PRO1298"},{"function":"Catalyzes the initial step of dolichol-linked oligosaccharide biosynthesis in N-linked protein glycosylation pathway: transfers GlcNAc-1-P from UDP-GlcNAc onto the carrier lipid dolichyl phosphate (P-dolichol), yielding GlcNAc-P-P-dolichol., [UniProtKB]; Data suggest that N-acetylglucosaminyl 1-phosphate transferase is a breast cancer therapeutic target., [RefSeq]; Present work improves our knowledge of DPAGT1-CDG and provides bases for developing tailored splicing and folding therapies Publication Status: Online-Only, [RefSeq]; We studied serum asialotransferrin (2009), which revealed a type 1 pattern compatible with type 1 glycosylation. Diagnosis of DPAGT1-CDG was confirmed by massive sequencing, which identified 2 mutations: c.329T\u003eC (p.Phe110Ser, which had not previously been described), and c.902G\u003eA (p.Arg301His) in the DPAGT1 gene., [RefSeq]","uniprot_canonical_ac":"Q9H3H5-1","publication_count":11,"reported_o_glycosites_with_glycan":1,"protein_name":"UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase","protein_names_uniprotkb":"UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase; N-acetylglucosamine-1-phosphate transferase; 2.7.8.15; GPT; GlcNAc-1-P transferase; G1PT","gene_names_refseq":"DPAGT1; ALG7; CDG-Ij; CDG1J; CMS13; CMSTA2; D11S366; DGPT; DPAGT; DPAGT2; G1PT; GPT; UAGT; UGAT","refseq_ac":"NP_001373.2","protein_names_refseq":"UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase; UDP-GlcNAc:dolichyl-phosphate N-acetylglucosaminephosphotransferase; N-acetylglucosamine-1-phosphate transferase; GlcNAc-1-P transferase 1; dolichyl-phosphate alpha-N-acetylglucosaminyltransferase; dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P tra; dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase); UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase 1","disease":"congenital disorder of glycosylation Ij (Disease Ontology:DOID:0080562); congenital myasthenic syndrome 13 (Disease Ontology:DOID:0110676)","reported_n_glycosites":0,"mass":46090.0,"refseq_name":"UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase","reported_n_glycosites_with_glycan":0,"reported_o_glycosites":0,"predicted_glycosites":1,"tax_id":9606,"organism":"Homo sapiens","pathway":"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (R-HSA-446193);  (hsa:1798); Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2 (R-HSA-4549356)","gene_name":"DPAGT1","gene_names_uniprotkb":"DPAGT1; DPAGT2"},{"function":"ALG13 and ALG14 form a functional endoplasmic reticulum UDP-N-acetylglucosamine transferase, [RefSeq]; May be involved in protein N-glycosylation. May play a role in the second step of the dolichol-linked oligosaccharide pathway. May anchor the catalytic subunit ALG13 to the ER., [UniProtKB]; New ALG14 congenital disorder of glycosylation with early and lethal neurodegeneration with myasthenic and myopathic features., [RefSeq]; We identify ALG14 and ALG2 as novel genes in which mutations cause a congenital myasthenic syndrome, [RefSeq]","uniprot_canonical_ac":"Q96F25-1","publication_count":3,"reported_o_glycosites_with_glycan":0,"protein_name":"UDP-N-acetylglucosamine transferase subunit ALG14 homolog","protein_names_uniprotkb":"UDP-N-acetylglucosamine transferase subunit ALG14 homolog","gene_names_refseq":"CMS15; ALG14","refseq_ac":"NP_001292171.1","protein_names_refseq":"UDP-N-acetylglucosamine transferase subunit ALG14 homolog; UDP-N-acetylglucosamine transferase subunit ALG14 homolog isoform 2","disease":"congenital myasthenic syndrome 15 (Disease Ontology:DOID:0110658)","reported_n_glycosites":0,"mass":24151.0,"refseq_name":"UDP-N-acetylglucosamine transferase subunit ALG14 homolog isoform 2","reported_n_glycosites_with_glycan":0,"reported_o_glycosites":0,"predicted_glycosites":0,"tax_id":9606,"organism":"Homo sapiens","pathway":" (hsa:199857); Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS) (R-HSA-5633231); Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (R-HSA-446193)","gene_name":"ALG14","gene_names_uniprotkb":"ALG14"},{"function":"Study presents molecular, clinical and biochemical findings in the largest collection of ALG1-CDG cases ever reported at a single time with 39 cases, bringing the total number to 57. This ranks it the third most common CDG type behind PMM2-CDG and ALG6-CDG. In addition, highly lethal genotype were identified and confirm the presence of a unique xeno-tetrasaccharide in ALG1-CDG patients., [RefSeq]; Participates in the formation of the lipid-linked precursor oligosaccharide for N-glycosylation. Involved in assembling the dolichol-pyrophosphate-GlcNAc(2)-Man(5) intermediate on the cytoplasmic surface of the ER., [UniProtKB]; Family study defining the phenotype of deficiency of beta-1,4 mannosyltransferase (MT-1) congenital disorder of glycosylation (CDG), due to ALG1 gene mutations. Four novel ALG1 mutations were identified., [RefSeq]; Was detected in the patient's ALG1-coding sequence., [RefSeq]; Evaluated the genetic association of WDR3 and ALG1 in schizophrenia. We examined 21 single nucleotide polymorphisms [SNPs; W1 (rs1812607)-W16 (rs6656360), A1 (rs8053916)-A10 (rs9673733)] from these genes using the Japanese case-control sample (1,808 schizophrenics and 2,170 matched controls). No significant genetic associations of these SNPs were identified. However, we detected a significant association of W4 (rs319471) Publication Status: Online-Only, [RefSeq]","uniprot_canonical_ac":"Q9BT22-1","publication_count":13,"reported_o_glycosites_with_glycan":1,"protein_name":"Chitobiosyldiphosphodolichol beta-mannosyltransferase","protein_names_uniprotkb":"Chitobiosyldiphosphodolichol beta-mannosyltransferase; GDP-Man:GlcNAc2-PP-dolichol mannosyltransferase; 2.4.1.142; Asparagine-linked glycosylation protein 1 homolog; GDP-mannose-dolichol diphosphochitobiose mannosyltransferase; hMat-1; Beta-1,4-mannosyltransferase; MT-1; Mannosyltransferase-1","gene_names_refseq":"CDG1K; hMat-1; HMAT1; HMT-1; HMT1; Mat-1; MT-1; ALG1","refseq_ac":"NP_001317433.1","protein_names_refseq":"chitobiosyldiphosphodolichol beta-mannosyltransferase isoform 2; asparagine-linked glycosylation 1 homolog (yeast, beta-1,4-mannosyltransferase); chitobiosyldiphosphodolichol beta-mannosyltransferase; GDP-mannose-dolichol diphosphochitobiose mannosyltransferase; GDP-Man:GlcNAc2-PP-dolichol mannosyltransferase; mannosyltransferase-1; asparagine-linked glycosylation protein 1 homolog; asparagine-linked glycosylation 1, beta-1,4-mannosyltransferase homolog","disease":"congenital disorder of glycosylation Ik (Disease Ontology:DOID:0080563)","reported_n_glycosites":0,"mass":52518.0,"refseq_name":"chitobiosyldiphosphodolichol beta-mannosyltransferase isoform 2","reported_n_glycosites_with_glycan":0,"reported_o_glycosites":0,"predicted_glycosites":0,"tax_id":9606,"organism":"Homo sapiens","pathway":"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (R-HSA-446193); Defective ALG1 causes ALG1-CDG (CDG-1k) (R-HSA-4549380);  (hsa:56052)","gene_name":"ALG1","gene_names_uniprotkb":"ALG1; PSEC0061; PRO1870; HMAT1; HMT1"},{"function":"Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans., [UniProtKB]; We also demonstrated that overexpression of FUT8 might be responsible for the decreased PSA expression in prostate cancer specimens. To our knowledge, this is the first study reporting the functional role of fucosylated enzyme in the development of castration-resistant prostate cancer., [RefSeq]; Expression in relation to p53 is a prognostic biomarker for patients with stage II and III colorectal cancer Publication Status: Online-Only, [RefSeq]; Expression of FUT8 is regulated by three different promoters, starting transcription in exons A, B, or C., [RefSeq]; Our results reveal a positive feedback mechanism of FUT8-mediated receptor core fucosylation that promotes TGF-b signaling and EMT, thus stimulating breast cancer cell invasion and metastasis. Publication Status: Online-Only, [RefSeq]; Loss of function mutations in FUT8 cause a congenital disorder of glycosylation (FUT8-CDG) characterized by defective core fucosylation., [RefSeq]","uniprot_canonical_ac":"Q9BYC5-1","publication_count":12,"reported_o_glycosites_with_glycan":0,"protein_name":"Alpha-(1,6)-fucosyltransferase","protein_names_uniprotkb":"Alpha-(1,6)-fucosyltransferase; Fucosyltransferase 8; GDP-fucose--glycoprotein fucosyltransferase; 2.4.1.68; Glycoprotein 6-alpha-L-fucosyltransferase; Alpha1-6FucT; GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase","gene_names_refseq":"FUT8; CDGF; CDGF1","refseq_ac":"NP_004471.4","protein_names_refseq":"glycoprotein 6-alpha-L-fucosyltransferase; GDP-fucose--glycoprotein fucosyltransferase; GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase; alpha1-6FucT; alpha-(1,6)-fucosyltransferase; fucosyltransferase 8 (alpha (1,6) fucosyltransferase); alpha-(1,6)-fucosyltransferase isoform b","disease":"congenital disorder of glycosylation with defective fucosylation (MONDO:MONDO:0060720)","reported_n_glycosites":0,"mass":66516.0,"refseq_name":"alpha-(1,6)-fucosyltransferase isoform b","reported_n_glycosites_with_glycan":0,"reported_o_glycosites":0,"predicted_glycosites":0,"tax_id":9606,"organism":"Homo sapiens","pathway":"Reactions specific to the complex N-glycan synthesis pathway (R-HSA-975578);  (hsa:2530)","gene_name":"FUT8","gene_names_uniprotkb":"FUT8"}],"list_id":"82f8556498fd4dc3d2c9da7dac268e6d"}
{"_id":{"$oid":"5fa64be5b8171e5125563417"},"query":{"execution_time":"2020-11-07 02:25:25 EST-0500","glytoucan_ac":"G74290AC","organism":{"id":9606,"name":"Homo sapiens"}},"results":[{"uniprot_canonical_ac":"Q96F25-1","gene_link":"https://www.uniprot.org/uniprot/Q96F25","protein_name":"","chromosome":"1","start_pos":95072898,"end_pos":94983079,"organism":"Homo sapiens","gene_name":"ALG14","tax_id":9606},{"uniprot_canonical_ac":"O60909-1","gene_link":"https://www.uniprot.org/uniprot/O60909","protein_name":"","chromosome":"1","start_pos":43990445,"end_pos":43981161,"organism":"Homo sapiens","gene_name":"B4GALT2","tax_id":9606},{"uniprot_canonical_ac":"Q9H3H5-1","gene_link":"https://www.uniprot.org/uniprot/Q9H3H5","protein_name":"","chromosome":"11","start_pos":119101655,"end_pos":119097001,"organism":"Homo sapiens","gene_name":"DPAGT1","tax_id":9606},{"uniprot_canonical_ac":"Q9Y274-1","gene_link":"https://www.uniprot.org/uniprot/Q9Y274","protein_name":"","chromosome":"3","start_pos":98793758,"end_pos":98768441,"organism":"Homo sapiens","gene_name":"ST3GAL6","tax_id":9606},{"uniprot_canonical_ac":"Q9NP73-1","gene_link":"https://www.uniprot.org/uniprot/Q9NP73","protein_name":"","chromosome":"X","start_pos":111759996,"end_pos":111681219,"organism":"Homo sapiens","gene_name":"ALG13","tax_id":9606},{"uniprot_canonical_ac":"P15291-1","gene_link":"https://www.uniprot.org/uniprot/P15291","protein_name":"","chromosome":"9","start_pos":33167169,"end_pos":33113457,"organism":"Homo sapiens","gene_name":"B4GALT1","tax_id":9606},{"uniprot_canonical_ac":"Q92685-1","gene_link":"https://www.uniprot.org/uniprot/Q92685","protein_name":"","chromosome":"3","start_pos":184248940,"end_pos":184242517,"organism":"Homo sapiens","gene_name":"ALG3","tax_id":9606},{"uniprot_canonical_ac":"Q9H553-1","gene_link":"https://www.uniprot.org/uniprot/Q9H553","protein_name":"","chromosome":"9","start_pos":99221894,"end_pos":99217937,"organism":"Homo sapiens","gene_name":"ALG2","tax_id":9606},{"uniprot_canonical_ac":"Q11206-1","gene_link":"https://www.uniprot.org/uniprot/Q11206","protein_name":"","chromosome":"11","start_pos":126414044,"end_pos":126406156,"organism":"Homo sapiens","gene_name":"ST3GAL4","tax_id":9606},{"uniprot_canonical_ac":"P26572-1","gene_link":"https://www.uniprot.org/uniprot/P26572","protein_name":"","chromosome":"5","start_pos":180792971,"end_pos":180791637,"organism":"Homo sapiens","gene_name":"MGAT1","tax_id":9606},{"uniprot_canonical_ac":"Q11203-1","gene_link":"https://www.uniprot.org/uniprot/Q11203","protein_name":"","chromosome":"1","start_pos":43930218,"end_pos":43736263,"organism":"Homo sapiens","gene_name":"ST3GAL3","tax_id":9606},{"uniprot_canonical_ac":"O60512-1","gene_link":"https://www.uniprot.org/uniprot/O60512","protein_name":"","chromosome":"1","start_pos":161176060,"end_pos":161171819,"organism":"Homo sapiens","gene_name":"B4GALT3","tax_id":9606},{"uniprot_canonical_ac":"Q9BT22-1","gene_link":"https://www.uniprot.org/uniprot/Q9BT22","protein_name":"","chromosome":"16","start_pos":5084878,"end_pos":5071850,"organism":"Homo sapiens","gene_name":"ALG1","tax_id":9606}],"list_id":"26f48dc2eec666f4214fdee7413b7324"}
{"_id":{"$oid":"60526ad1b8171e71093afe6b"},"query":{"execution_time":"2021-03-17 16:47:13 EDT-0400","glytoucan_ac":"G17689DH","organism":{"id":9606,"name":"Homo sapiens"}},"results":[{"uniprot_canonical_ac":"Q9H3H5-1","gene_link":"https://www.uniprot.org/uniprot/Q9H3H5","protein_name":"UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase","chromosome":"11","start_pos":119101655,"end_pos":119097001,"organism":"Homo sapiens","gene_name":"DPAGT1","tax_id":9606},{"uniprot_canonical_ac":"Q9Y274-1","gene_link":"https://www.uniprot.org/uniprot/Q9Y274","protein_name":"Type 2 lactosamine alpha-2,3-sialyltransferase","chromosome":"3","start_pos":98793758,"end_pos":98768441,"organism":"Homo sapiens","gene_name":"ST3GAL6","tax_id":9606},{"uniprot_canonical_ac":"Q9NP73-1","gene_link":"https://www.uniprot.org/uniprot/Q9NP73","protein_name":"Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13","chromosome":"X","start_pos":111759996,"end_pos":111681219,"organism":"Homo sapiens","gene_name":"ALG13","tax_id":9606},{"uniprot_canonical_ac":"O60512-1","gene_link":"https://www.uniprot.org/uniprot/O60512","protein_name":"Beta-1,4-galactosyltransferase 3","chromosome":"1","start_pos":161176060,"end_pos":161171819,"organism":"Homo sapiens","gene_name":"B4GALT3","tax_id":9606},{"uniprot_canonical_ac":"Q9BYC5-1","gene_link":"https://www.uniprot.org/uniprot/Q9BYC5","protein_name":"Alpha-(1,6)-fucosyltransferase","chromosome":"14","start_pos":65742407,"end_pos":65561564,"organism":"Homo sapiens","gene_name":"FUT8","tax_id":9606},{"uniprot_canonical_ac":"Q11206-1","gene_link":"https://www.uniprot.org/uniprot/Q11206","protein_name":"CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4","chromosome":"11","start_pos":126414044,"end_pos":126406156,"organism":"Homo sapiens","gene_name":"ST3GAL4","tax_id":9606},{"uniprot_canonical_ac":"Q10469-1","gene_link":"https://www.uniprot.org/uniprot/Q10469","protein_name":"Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase","chromosome":"14","start_pos":49622609,"end_pos":49621269,"organism":"Homo sapiens","gene_name":"MGAT2","tax_id":9606},{"uniprot_canonical_ac":"Q11203-1","gene_link":"https://www.uniprot.org/uniprot/Q11203","protein_name":"CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase","chromosome":"1","start_pos":43930218,"end_pos":43736263,"organism":"Homo sapiens","gene_name":"ST3GAL3","tax_id":9606},{"uniprot_canonical_ac":"Q96F25-1","gene_link":"https://www.uniprot.org/uniprot/Q96F25","protein_name":"UDP-N-acetylglucosamine transferase subunit ALG14 homolog","chromosome":"1","start_pos":95072898,"end_pos":94983079,"organism":"Homo sapiens","gene_name":"ALG14","tax_id":9606},{"uniprot_canonical_ac":"P26572-1","gene_link":"https://www.uniprot.org/uniprot/P26572","protein_name":"Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase","chromosome":"5","start_pos":180792971,"end_pos":180791637,"organism":"Homo sapiens","gene_name":"MGAT1","tax_id":9606},{"uniprot_canonical_ac":"Q9BT22-1","gene_link":"https://www.uniprot.org/uniprot/Q9BT22","protein_name":"Chitobiosyldiphosphodolichol beta-mannosyltransferase","chromosome":"16","start_pos":5084878,"end_pos":5071850,"organism":"Homo sapiens","gene_name":"ALG1","tax_id":9606},{"uniprot_canonical_ac":"Q9H553-1","gene_link":"https://www.uniprot.org/uniprot/Q9H553","protein_name":"Alpha-1,3/1,6-mannosyltransferase ALG2","chromosome":"9","start_pos":99221894,"end_pos":99217937,"organism":"Homo sapiens","gene_name":"ALG2","tax_id":9606},{"uniprot_canonical_ac":"P15291-1","gene_link":"https://www.uniprot.org/uniprot/P15291","protein_name":"Beta-1,4-galactosyltransferase 1","chromosome":"9","start_pos":33167169,"end_pos":33113457,"organism":"Homo sapiens","gene_name":"B4GALT1","tax_id":9606},{"uniprot_canonical_ac":"O60909-1","gene_link":"https://www.uniprot.org/uniprot/O60909","protein_name":"Beta-1,4-galactosyltransferase 2","chromosome":"1","start_pos":43990445,"end_pos":43981161,"organism":"Homo sapiens","gene_name":"B4GALT2","tax_id":9606}],"list_id":"dc6c48316a12e3f4a3bcb0bd4b9e0d76"}
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